PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,282 sequences; 206,678,396 total letters
Results from round 1
Query= sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score E
Sequences producing significant alignments: (Bits) Value
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 14775 0.0
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 14454 0.0
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 14167 0.0
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 14123 0.0
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 12939 0.0
sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respi... 9103 0.0
sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus R... 8822 0.0
sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus H... 8547 0.0
sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 2... 8495 0.0
sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute resp... 7475 0.0
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 6150 0.0
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 6106 0.0
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 5980 0.0
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 5451 0.0
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 5449 0.0
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 5437 0.0
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 5429 0.0
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 5418 0.0
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 5408 0.0
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 5356 0.0
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 5319 0.0
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 5317 0.0
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 5312 0.0
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 5287 0.0
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 4328 0.0
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 4295 0.0
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 4286 0.0
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 4258 0.0
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 4194 0.0
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 4173 0.0
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 4133 0.0
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 4133 0.0
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 4131 0.0
sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus H... 2335 0.0
sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus H... 2288 0.0
sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respi... 2184 0.0
sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronaviru... 1887 0.0
sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronaviru... 1885 0.0
sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus... 1879 0.0
sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus... 1875 0.0
sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus... 1873 0.0
sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus... 1860 0.0
sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronaviru... 1850 0.0
sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronaviru... 1843 0.0
sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus... 1810 0.0
sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus... 1808 0.0
sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus... 1803 0.0
sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 5... 1209 0.0
sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic ... 1188 0.0
sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus... 1184 0.0
sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus... 1176 0.0
sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmiss... 1117 0.0
sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious ... 1094 0.0
sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious b... 1094 0.0
sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious b... 1092 0.0
sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porc... 513 1e-160
sp|Q9WQ77|R1AB_CVRSD Replicase polyprotein 1ab (Fragment) OS=Rat ... 484 4e-154
sp|Q9WQ76|R1AB_CVTMI Replicase polyprotein 1ab (Fragment) OS=Turk... 442 2e-139
sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian... 442 3e-136
sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus H... 310 2e-82
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 310 3e-82
sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 1... 308 1e-81
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 308 1e-81
sp|P36697|R1AB_CVCAI Replicase polyprotein 1ab (Fragment) OS=Cani... 179 7e-50
sp|Q04158|R1AB_CVPR8 Replicase polyprotein 1ab (Fragment) OS=Porc... 128 2e-32
sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11... 135 2e-29
sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream vir... 130 4e-28
sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus 1 OX... 127 5e-27
sp|Q97UU4|Y2899_SACS2 Uncharacterized protein SSO2899 OS=Saccharo... 68.2 7e-11
sp|Q8ZXT3|Y1111_PYRAE Uncharacterized protein PAE1111 OS=Pyrobacu... 68.2 9e-11
sp|Q9WYX8|Y508_THEMA Uncharacterized protein TM_0508 OS=Thermotog... 72.4 1e-10
sp|Q4J9D2|Y1252_SULAC Uncharacterized protein Saci_1252 OS=Sulfol... 67.8 1e-10
sp|Q96XY5|Y2383_SULTO Uncharacterized protein STK_23830 OS=Sulfur... 62.4 7e-09
sp|P0C6F3|R1A_BEV Replicase polyprotein 1a OS=Berne virus OX=1115... 65.1 3e-08
sp|A7MG20|YMDB_CROS8 O-acetyl-ADP-ribose deacetylase OS=Cronobact... 59.3 8e-08
sp|B5F961|YMDB_SALA4 O-acetyl-ADP-ribose deacetylase OS=Salmonell... 58.5 2e-07
sp|P0C6F4|R1A_BRV1 Replicase polyprotein 1a OS=Breda virus 1 OX=3... 62.4 2e-07
sp|A8AI35|YMDB_CITK8 O-acetyl-ADP-ribose deacetylase OS=Citrobact... 58.2 2e-07
sp|P67341|YMDB_SALTY O-acetyl-ADP-ribose deacetylase OS=Salmonell... 56.6 8e-07
sp|P67342|YMDB_SALTI O-acetyl-ADP-ribose deacetylase OS=Salmonell... 56.6 8e-07
sp|B4T2X8|YMDB_SALNS O-acetyl-ADP-ribose deacetylase OS=Salmonell... 55.8 1e-06
sp|B6SFA4|MAA3_ARATH Probable helicase MAGATAMA 3 OS=Arabidopsis ... 58.5 2e-06
sp|P0A8D6|YMDB_ECOLI O-acetyl-ADP-ribose deacetylase OS=Escherich... 55.1 3e-06
sp|P0A8D7|YMDB_ECOL6 O-acetyl-ADP-ribose deacetylase OS=Escherich... 55.1 3e-06
sp|P0A8D8|YMDB_ECO57 O-acetyl-ADP-ribose deacetylase OS=Escherich... 55.1 3e-06
sp|B5RBF3|YMDB_SALG2 O-acetyl-ADP-ribose deacetylase OS=Salmonell... 54.3 4e-06
sp|C9Y0V8|YMDB_CROTZ O-acetyl-ADP-ribose deacetylase OS=Cronobact... 54.3 4e-06
sp|D3RKJ0|YMDB_KLEVT O-acetyl-ADP-ribose deacetylase OS=Klebsiell... 53.9 5e-06
sp|B5XXK9|YMDB_KLEP3 O-acetyl-ADP-ribose deacetylase OS=Klebsiell... 53.9 5e-06
sp|Q8CAS9|PARP9_MOUSE Protein mono-ADP-ribosyltransferase PARP9 O... 55.8 2e-05
sp|Q0T5Z6|YMDB_SHIF8 O-acetyl-ADP-ribose deacetylase OS=Shigella ... 52.4 2e-05
sp|A4W960|YMDB_ENT38 O-acetyl-ADP-ribose deacetylase OS=Enterobac... 52.4 2e-05
sp|Q460N5|PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14 ... 55.8 2e-05
sp|B7LT90|YMDB_ESCF3 O-acetyl-ADP-ribose deacetylase OS=Escherich... 52.0 2e-05
sp|D2TT52|YMDB_CITRI O-acetyl-ADP-ribose deacetylase OS=Citrobact... 52.0 3e-05
sp|P36327|POLN_EEVV3 Polyprotein P1234 OS=Venezuelan equine encep... 55.5 3e-05
sp|Q8RHQ2|Y1951_FUSNN Uncharacterized protein FN1951 OS=Fusobacte... 52.0 3e-05
sp|Q32E73|YMDB_SHIDS O-acetyl-ADP-ribose deacetylase OS=Shigella ... 51.6 3e-05
sp|P27282|POLN_EEVVT Polyprotein P1234 OS=Venezuelan equine encep... 54.7 4e-05
sp|P36328|POLN_EEVVP Polyprotein P1234 OS=Venezuelan equine encep... 54.7 4e-05
sp|D5CE05|YMDB_ENTCC O-acetyl-ADP-ribose deacetylase OS=Enterobac... 50.8 7e-05
sp|Q8IXQ6|PARP9_HUMAN Protein mono-ADP-ribosyltransferase PARP9 O... 52.0 2e-04
sp|Q87JZ5|Y4103_VIBPA Macro domain-containing protein VPA0103 OS=... 48.5 4e-04
sp|Q8V294|POLN_EEVVC Polyprotein P1234 OS=Venezuelan equine encep... 51.6 4e-04
sp|Q8RB30|Y995_CALS4 Macro domain-containing protein TTE0995 OS=C... 47.8 7e-04
sp|Q2EMV9|PAR14_MOUSE Protein mono-ADP-ribosyltransferase PARP14 ... 50.4 8e-04
sp|Q8KAE4|Y2219_CHLTE Macro domain-containing protein CT2219 OS=C... 46.6 0.001
sp|P38859|DNA2_YEAST DNA replication ATP-dependent helicase/nucle... 49.7 0.001
sp|Q92355|SEN1_SCHPO Helicase sen1 OS=Schizosaccharomyces pombe (... 49.3 0.002
sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 OS=Arabidopsis th... 49.3 0.002
sp|Q8EYT0|Y4133_LEPIN Macro domain-containing protein LA_4133 OS=... 46.2 0.002
sp|Q72M93|Y3295_LEPIC Macro domain-containing protein LIC_13295 O... 46.2 0.002
sp|Q8Y2K1|Y334_RALN1 Macro domain-containing protein RSc0334 OS=R... 46.2 0.002
sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reprodu... 48.9 0.002
sp|Q9WJC7|POLN_EEVVM Polyprotein P1234 OS=Venezuelan equine encep... 48.9 0.003
sp|Q93SX7|Y189_ACISE Macro domain-containing protein OS=Acinetoba... 46.2 0.003
sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reprodu... 48.5 0.003
sp|E1SDF1|YMDB1_PANVC O-acetyl-ADP-ribose deacetylase 1 OS=Pantoe... 45.4 0.004
sp|Q7MTZ7|MACRO_PORGI Macro domain-containing protein PG1779 OS=P... 45.4 0.004
sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhag... 48.1 0.005
sp|Q8Q0F9|Y177_METMA Macro domain-containing protein MM_0177 OS=M... 45.1 0.007
sp|A6YQT5|RPOA_PRRSV Replicase polyprotein 1ab OS=Porcine reprodu... 47.4 0.008
sp|P30771|RENT1_YEAST ATP-dependent helicase NAM7 OS=Saccharomyce... 46.2 0.016
sp|Q88SK6|Y3408_LACPL Macro domain-containing protein lp_3408 OS=... 43.5 0.020
sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reprodu... 45.8 0.024
sp|Q9ZBG3|Y6450_STRCO Macro domain-containing protein SCO6450 OS=... 43.1 0.025
sp|O28751|Y1521_ARCFU ADP-ribose glycohydrolase AF_1521 OS=Archae... 43.1 0.036
sp|P13896|POLN_WEEV Polyprotein P1234 OS=Western equine encephali... 45.1 0.037
sp|O59182|Y1513_PYRHO Uncharacterized protein PH1513 OS=Pyrococcu... 42.0 0.066
sp|Q4QXJ8|POLN_EEEVF Polyprotein P1234 OS=Eastern equine encephal... 44.3 0.069
sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteriti... 43.9 0.085
sp|P05720|YCX1_AUXPY Uncharacterized 12.7 kDa protein in 16S-23S ... 40.0 0.11
sp|Q71W03|Y2748_LISMF Macro domain-containing protein LMOf2365_27... 41.2 0.13
sp|Q8Y3S3|Y2759_LISMO Macro domain-containing protein lmo2759 OS=... 40.8 0.14
sp|Q306W6|POLN_EEEV1 Polyprotein P1234 OS=Eastern equine encephal... 43.1 0.15
sp|Q9V0Y3|Y656_PYRAB Uncharacterized protein PYRAB06560 OS=Pyroco... 40.8 0.17
sp|Q926Y8|Y2902_LISIN Macro domain-containing protein lin2902 OS=... 40.4 0.18
sp|Q9UTG3|YKEE_SCHPO Uncharacterized protein C1805.14 OS=Schizosa... 42.0 0.22
sp|Q8P5Z8|Y3184_XANCP Macro domain-containing protein XCC3184 OS=... 40.0 0.27
sp|A0A1P8ASY1|JHS1_ARATH DNA replication ATP-dependent helicase/n... 42.0 0.27
sp|Q8TQD0|Y1614_METAC Macro domain-containing protein MA_1614 OS=... 40.4 0.30
sp|Q9HXU7|Y3693_PSEAE Macro domain-containing protein PA3693 OS=P... 39.7 0.40
sp|Q8K4G6|MACD1_RAT ADP-ribose glycohydrolase MACROD1 (Fragment) ... 40.4 0.43
sp|Q9BQ69|MACD1_HUMAN ADP-ribose glycohydrolase MACROD1 OS=Homo s... 40.4 0.47
sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens ... 41.2 0.49
sp|Q9BYK8|HELZ2_HUMAN 3'-5' exoribonuclease HELZ2 OS=Homo sapiens... 41.2 0.54
sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 homolog... 40.8 0.57
sp|Q9RUV0|PPDE_DEIRA Phosphatase/phosphodiesterase DR_1281 OS=Dei... 39.7 0.68
sp|A2AKX3|SETX_MOUSE Probable helicase senataxin OS=Mus musculus ... 40.8 0.77
sp|Q09449|YQ12_CAEEL Uncharacterized ATP-dependent helicase C05C1... 40.4 0.80
sp|Q97AU0|Y719_THEVO Uncharacterized protein TV0719 OS=Thermoplas... 38.9 0.80
sp|Q8PHB6|Y3343_XANAC Macro domain-containing protein XAC3343 OS=... 38.5 0.83
sp|Q09820|RENT1_SCHPO ATP-dependent helicase upf1 OS=Schizosaccha... 40.4 0.85
sp|Q306W8|POLN_EEEV8 Polyprotein P1234 OS=Eastern equine encephal... 40.4 0.85
sp|P18479|POLG_ZYMVC Genome polyprotein OS=Zucchini yellow mosaic... 40.4 0.86
sp|Q9HJ67|Y1105_THEAC Uncharacterized protein Ta1105 OS=Thermopla... 38.9 0.88
sp|Q6PAV8|MACD2_XENLA ADP-ribose glycohydrolase MACROD2 OS=Xenopu... 40.0 0.93
sp|Q9FJR0|RENT1_ARATH Regulator of nonsense transcripts 1 homolog... 40.4 0.96
sp|P32644|ECM32_YEAST Putative ATP-dependent RNA helicase ECM32 O... 40.0 1.1
sp|Q922B1|MACD1_MOUSE ADP-ribose glycohydrolase MACROD1 OS=Mus mu... 39.3 1.2
sp|Q9EYI6|Y189_STRNO Macro domain-containing protein in sno 5'reg... 38.1 1.2
sp|Q180E9|TIG_CLOD6 Trigger factor OS=Clostridioides difficile (s... 39.7 1.2
sp|P26627|R1AB_CVMJD Replicase polyprotein 1ab (Fragment) OS=Muri... 39.7 1.3
sp|C4L602|RIMM_EXISA Ribosome maturation factor RimM OS=Exiguobac... 37.7 1.7
sp|O40955|POLN_RUBVR Non-structural polyprotein p200 OS=Rubella v... 39.3 2.1
sp|Q8BCR0|POLN_RUBVN Non-structural polyprotein p200 OS=Rubella v... 39.3 2.2
sp|Q7TZB9|Y1934_MYCBO Uncharacterized protein Mb1934c OS=Mycobact... 38.5 2.3
sp|P9WK29|Y1899_MYCTU Uncharacterized protein Rv1899c OS=Mycobact... 38.5 2.3
sp|P9WK28|Y1899_MYCTO Uncharacterized protein MT1950 OS=Mycobacte... 38.5 2.3
sp|Q2KHU5|MACD1_BOVIN ADP-ribose glycohydrolase MACROD1 OS=Bos ta... 38.1 2.6
sp|P18478|POLG_WMV2U Genome polyprotein (Fragment) OS=Watermelon ... 38.5 3.1
sp|Q98TR3|RENT1_TAKRU Putative regulator of nonsense transcripts ... 38.5 3.1
sp|Q985D2|Y7730_RHILO Macro domain-containing protein mll7730 OS=... 37.0 3.2
sp|Q54I89|RENT1_DICDI Regulator of nonsense transcripts 1 OS=Dict... 38.5 3.2
sp|Q5TB80|CE162_HUMAN Centrosomal protein of 162 kDa OS=Homo sapi... 38.5 3.4
sp|E1PL40|YMDB2_PANVC O-acetyl-ADP-ribose deacetylase 2 OS=Pantoe... 36.6 3.5
sp|O76512|RENT1_CAEEL Regulator of nonsense transcripts 1 OS=Caen... 38.5 3.6
sp|Q04561|RPOA_PRRSL Replicase polyprotein 1ab OS=Porcine reprodu... 38.5 3.7
sp|Q5ZKG3|DNA2_CHICK DNA replication ATP-dependent helicase/nucle... 38.1 4.5
sp|E9QAM5|HELZ2_MOUSE 3'-5' exoribonuclease HELZ2 OS=Mus musculus... 38.1 4.5
sp|P13889|POLN_RUBVT Non-structural polyprotein p200 OS=Rubella v... 38.1 4.7
sp|A0A339|NDHK_COFAR NAD(P)H-quinone oxidoreductase subunit K, ch... 37.0 4.9
sp|Q06502|RPOA_LDVC Replicase polyprotein 1ab OS=Lactate dehydrog... 38.1 5.1
sp|A0MD28|RPOA_PRRSS Replicase polyprotein 1ab OS=Porcine reprodu... 38.1 5.2
sp|Q89330|POLG_ZYMVR Genome polyprotein OS=Zucchini yellow mosaic... 37.7 6.1
sp|A1Z1Q3|MACD2_HUMAN ADP-ribose glycohydrolase MACROD2 OS=Homo s... 37.0 7.1
sp|Q3ZX83|TIG_DEHMC Trigger factor OS=Dehalococcoides mccartyi (s... 37.0 8.6
sp|O60306|AQR_HUMAN RNA helicase aquarius OS=Homo sapiens OX=9606... 37.0 9.7
sp|Q83017|RPOA_LDVP Replicase polyprotein 1ab OS=Lactate dehydrog... 37.0 10.0
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 14775 bits (38346), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 7073/7073 (100%), Positives = 7073/7073 (100%), Gaps = 0/7073 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW
Sbjct 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL
Sbjct 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY
Sbjct 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV
Sbjct 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC
Sbjct 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV
Sbjct 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL
Sbjct 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
Query 961 PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC 1020
PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC
Sbjct 961 PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC 1020
Query 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS
Sbjct 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
Query 1081 CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL 1140
CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL
Sbjct 1081 CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL 1140
Query 1141 QVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK 1200
QVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK
Sbjct 1141 QVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK 1200
Query 1201 PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP 1260
PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP
Sbjct 1201 PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP 1260
Query 1261 YMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKT 1320
YMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKT
Sbjct 1261 YMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKT 1320
Query 1321 ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQR 1380
ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQR
Sbjct 1321 ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQR 1380
Query 1381 KYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAAR 1440
KYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAAR
Sbjct 1381 KYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAAR 1440
Query 1441 CMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG 1500
CMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG
Sbjct 1441 CMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG 1500
Query 1501 VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQL 1560
VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQL
Sbjct 1501 VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQL 1560
Query 1561 VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFL 1620
VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFL
Sbjct 1561 VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFL 1620
Query 1621 GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR 1680
GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR
Sbjct 1621 GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR 1680
Query 1681 AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT 1740
AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT
Sbjct 1681 AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT 1740
Query 1741 GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC 1800
GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC
Sbjct 1741 GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC 1800
Query 1801 ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYK 1860
ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYK
Sbjct 1801 ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYK 1860
Query 1861 LDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQ 1920
LDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQ
Sbjct 1861 LDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQ 1920
Query 1921 MTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF 1980
MTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF
Sbjct 1921 MTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF 1980
Query 1981 KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE 2040
KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE
Sbjct 1981 KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE 2040
Query 2041 CDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA 2100
CDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA
Sbjct 2041 CDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA 2100
Query 2101 THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFT 2160
THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFT
Sbjct 2101 THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFT 2160
Query 2161 KSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSL 2220
KSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSL
Sbjct 2161 KSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSL 2220
Query 2221 ICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPA 2280
ICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPA
Sbjct 2221 ICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPA 2280
Query 2281 LETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW 2340
LETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW
Sbjct 2281 LETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW 2340
Query 2341 LMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC 2400
LMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC
Sbjct 2341 LMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC 2400
Query 2401 TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINP 2460
TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINP
Sbjct 2401 TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINP 2460
Query 2461 TDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVF 2520
TDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVF
Sbjct 2461 TDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVF 2520
Query 2521 DGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFS 2580
DGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFS
Sbjct 2521 DGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFS 2580
Query 2581 VPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDL 2640
VPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDL
Sbjct 2581 VPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDL 2640
Query 2641 EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE 2700
EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE
Sbjct 2641 EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE 2700
Query 2701 QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLA 2760
QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLA
Sbjct 2701 QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLA 2760
Query 2761 ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG 2820
ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG
Sbjct 2761 ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG 2820
Query 2821 SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLI 2880
SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLI
Sbjct 2821 SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLI 2880
Query 2881 EYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQ 2940
EYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQ
Sbjct 2881 EYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQ 2940
Query 2941 FPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA 3000
FPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA
Sbjct 2941 FPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA 3000
Query 3001 MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANAL 3060
MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANAL
Sbjct 3001 MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANAL 3060
Query 3061 LFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAI 3120
LFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAI
Sbjct 3061 LFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAI 3120
Query 3121 YVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ 3180
YVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ
Sbjct 3121 YVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ 3180
Query 3181 YNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQ 3240
YNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQ
Sbjct 3181 YNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQ 3240
Query 3241 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3300
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR
Sbjct 3241 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3300
Query 3301 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3301 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
Query 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK
Sbjct 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
Query 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
Query 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC
Sbjct 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
Query 3541 SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA 3600
SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA
Sbjct 3541 SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA 3600
Query 3601 CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCV 3660
CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCV
Sbjct 3601 CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCV 3660
Query 3661 MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN 3720
MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN
Sbjct 3661 MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN 3720
Query 3721 YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY
Sbjct 3721 YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
Query 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS
Sbjct 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
Query 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG
Sbjct 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
Query 3901 AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKS 3960
AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKS
Sbjct 3901 AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKS 3960
Query 3961 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4020
LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND
Sbjct 3961 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4020
Query 4021 ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD 4080
ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD
Sbjct 4021 ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD 4080
Query 4081 ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTAC 4140
ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTAC
Sbjct 4081 ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTAC 4140
Query 4141 TDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP 4200
TDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP
Sbjct 4141 TDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP 4200
Query 4201 KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDY 4260
KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDY
Sbjct 4201 KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDY 4260
Query 4261 LASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFC 4320
LASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFC
Sbjct 4261 LASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFC 4320
Query 4321 DLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRV 4380
DLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRV
Sbjct 4321 DLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRV 4380
Query 4381 CGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFV 4440
CGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFV
Sbjct 4381 CGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFV 4440
Query 4441 VKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYAL 4500
VKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYAL
Sbjct 4441 VKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYAL 4500
Query 4501 RHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQ 4560
RHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQ
Sbjct 4501 RHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQ 4560
Query 4561 FCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRAL 4620
FCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRAL
Sbjct 4561 FCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRAL 4620
Query 4621 AAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCA 4680
AAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCA
Sbjct 4621 AAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCA 4680
Query 4681 NFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKEL 4740
NFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKEL
Sbjct 4681 NFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKEL 4740
Query 4741 LVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKE 4800
LVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKE
Sbjct 4741 LVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKE 4800
Query 4801 GSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINAN 4860
GSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINAN
Sbjct 4801 GSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINAN 4860
Query 4861 QVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAK 4920
QVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAK
Sbjct 4861 QVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAK 4920
Query 4921 NRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
NRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET
Sbjct 4921 NRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
Query 4981 PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGG 5040
PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGG
Sbjct 4981 PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGG 5040
Query 5041 SLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECL 5100
SLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECL
Sbjct 5041 SLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECL 5100
Query 5101 YRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNN 5160
YRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNN
Sbjct 5101 YRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNN 5160
Query 5161 VFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTD 5220
VFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTD
Sbjct 5161 VFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTD 5220
Query 5221 GTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDN 5280
GTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDN
Sbjct 5221 GTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDN 5280
Query 5281 TSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSH 5340
TSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSH
Sbjct 5281 TSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSH 5340
Query 5341 KLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVG 5400
KLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVG
Sbjct 5341 KLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVG 5400
Query 5401 SDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLS 5460
SDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLS
Sbjct 5401 SDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLS 5460
Query 5461 DRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKL 5520
DRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKL
Sbjct 5461 DRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKL 5520
Query 5521 NVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYST 5580
NVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYST
Sbjct 5521 NVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYST 5580
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR
Sbjct 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI
Sbjct 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
Query 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN
Sbjct 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
Query 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN
Sbjct 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
Query 5821 AVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDR 5880
AVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDR
Sbjct 5821 AVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDR 5880
Query 5881 DLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGL 5940
DLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGL
Sbjct 5881 DLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGL 5940
Query 5941 CVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR 6000
CVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR
Sbjct 5941 CVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR 6000
Query 6001 DAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLP 6060
DAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLP
Sbjct 6001 DAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLP 6060
Query 6061 WNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFS 6120
WNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFS
Sbjct 6061 WNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFS 6120
Query 6121 TSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTR 6180
TSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTR
Sbjct 6121 TSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTR 6180
Query 6181 CLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAI 6240
CLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAI
Sbjct 6181 CLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAI 6240
Query 6241 KCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIV 6300
KCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIV
Sbjct 6241 KCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIV 6300
Query 6301 CRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQ 6360
CRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQ
Sbjct 6301 CRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQ 6360
Query 6361 VVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYN 6420
VVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYN
Sbjct 6361 VVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYN 6420
Query 6421 LWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPV 6480
LWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPV
Sbjct 6421 LWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPV 6480
Query 6481 NVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKP 6540
NVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKP
Sbjct 6481 NVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKP 6540
Query 6541 TESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGES 6600
TESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGES
Sbjct 6541 TESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGES 6600
Query 6601 VKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYA 6660
VKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYA
Sbjct 6601 VKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYA 6660
Query 6661 FEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCV 6720
FEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCV
Sbjct 6661 FEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCV 6720
Query 6721 CSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAW 6780
CSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAW
Sbjct 6721 CSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAW 6780
Query 6781 QPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNM 6840
QPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNM
Sbjct 6781 QPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNM 6840
Query 6841 RVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWD 6900
RVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWD
Sbjct 6841 RVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWD 6900
Query 6901 LIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMG 6960
LIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMG
Sbjct 6901 LIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMG 6960
Query 6961 HFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLF 7020
HFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLF
Sbjct 6961 HFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLF 7020
Query 7021 DMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
DMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN
Sbjct 7021 DMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 14454 bits (37513), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 6897/7074 (97%), Positives = 6982/7074 (99%), Gaps = 4/7074 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLVLG+NEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLK+GTCG+VELEKGV
Sbjct 1 MESLVLGINEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKSGTCGIVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQ EQPYVFIKRSDA T+HGH+V ELVAE+DG+QYGRSGITLGVLVPHVGETPIAYRN
Sbjct 61 LPQPEQPYVFIKRSDAQGTDHGHRVRELVAELDGVQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHS+GIDLKSYDLGDELGTDPIEDYEQNWNTKHGSG LRELTRELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGVLRELTRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
A+TRYVDNNFCGPDGYPL+CIKD LARAGKSMCTLSEQLDYIESKRGVYCCRDH HEIAW
Sbjct 181 ALTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCRDHGHEIAW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVA+PQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCE CGTENLV EGP TCGYL
Sbjct 301 RSVYPVATPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVSEGPNTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
PTNAVVKMPCPACQDPEIGPEHS ADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSAADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDF LNEEVAIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFQLNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKP+KGAWNIGQ RSVLTPLCGFPSQA
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPIKGAWNIGQHRSVLTPLCGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIF+RTLDAANHSIPDLQRAAVTILD ISEQSLRLVDAMVYTS+LLTNSVIIMAY
Sbjct 541 AGVIRSIFSRTLDAANHSIPDLQRAAVTILDSISEQSLRLVDAMVYTSNLLTNSVIIMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQTSQWLSNLL TTVEKLRPIF WIEAKLSAGVEFLKDAWEILKFLITGVFDIV
Sbjct 601 VTGGLVQQTSQWLSNLLDTTVEKLRPIFAWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVASDNIKDCVKCF+DVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC
Sbjct 661 KGQIQVASDNIKDCVKCFVDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGA+VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAVVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVC+NGLMLLEIK EQYCALSPGLLATNNVFRLKGGAP KGVTFGEDTV EVQGYKNV
Sbjct 781 TPVCINGLMLLEIKANEQYCALSPGLLATNNVFRLKGGAPTKGVTFGEDTVVEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDE-TCEHEYGTEDDYQG 959
WSVATFYLFDD+GEE SSRMYCSFYPPDEEE+ + EEEE+ E TCEHEYGTE+DY+G
Sbjct 901 WSVATFYLFDDSGEEKLSSRMYCSFYPPDEEEDCEEYEEEEEVSERTCEHEYGTEEDYKG 960
Query 960 LPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
LPLEFGAS + ++VEE+EEEDWLDD E EPEPEP EEPVNQ TGYLKLTDNVAIK
Sbjct 961 LPLEFGASTDIIQVEEQEEEDWLDDAVEA---EPEPEPLHEEPVNQLTGYLKLTDNVAIK 1017
Query 1020 CVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGG 1079
CVDIV+EAQ+ANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESD YIKLNGPLTVGG
Sbjct 1018 CVDIVEEAQNANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDHYIKLNGPLTVGG 1077
Query 1080 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1139
SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS
Sbjct 1078 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1137
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQ 1199
LQ+CVQTVRTQVYI VNDK LYEQVVMDYLD+LKP+VEAPKQE P E K +EKSVVQ
Sbjct 1138 LQMCVQTVRTQVYIVVNDKVLYEQVVMDYLDSLKPKVEAPKQEVLPKAEYPKVDEKSVVQ 1197
Query 1200 KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDA 1259
K +DVKPKIKACIDEVTTTLEETKFLTNKLLLF DINGKLY DS+NMLRGEDMSFLEKDA
Sbjct 1198 KTIDVKPKIKACIDEVTTTLEETKFLTNKLLLFTDINGKLYQDSKNMLRGEDMSFLEKDA 1257
Query 1260 PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAK 1319
PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVP++EYITTYPGQGCAGYTLEEAK
Sbjct 1258 PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPINEYITTYPGQGCAGYTLEEAK 1317
Query 1320 TALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQ 1379
TALKKCKSAFYVLPSE PNAKEEILGTVSWNLREMLAHAEETRKLMP+CMDVRAIMATIQ
Sbjct 1318 TALKKCKSAFYVLPSETPNAKEEILGTVSWNLREMLAHAEETRKLMPVCMDVRAIMATIQ 1377
Query 1380 RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA 1439
RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA
Sbjct 1378 RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA 1437
Query 1440 RCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTEL 1499
RCMRSLKAPA+VSVSSPDAVTTYNGYLTSSSKTSE+HFVETVSLAGSYRDWSYSGQRTEL
Sbjct 1438 RCMRSLKAPAIVSVSSPDAVTTYNGYLTSSSKTSEDHFVETVSLAGSYRDWSYSGQRTEL 1497
Query 1500 GVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQ 1559
GVEFLKRG+KIVYHTLESPV+FHLDGEVL LDKLKSLLSLREVKTIKVFTTVDNTNLHTQ
Sbjct 1498 GVEFLKRGEKIVYHTLESPVKFHLDGEVLPLDKLKSLLSLREVKTIKVFTTVDNTNLHTQ 1557
Query 1560 LVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF 1619
LVDMSMTYGQQ GPTYL+GADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF
Sbjct 1558 LVDMSMTYGQQLGPTYLEGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF 1617
Query 1620 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRA 1679
LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ+EVKFNAPALQEAYYRA
Sbjct 1618 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQIEVKFNAPALQEAYYRA 1677
Query 1680 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1739
RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL
Sbjct 1678 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1737
Query 1740 TGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL 1799
TGVEAVMYMGTLSYDNLK GVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL
Sbjct 1738 TGVEAVMYMGTLSYDNLKMGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL 1797
Query 1800 CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY 1859
CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY
Sbjct 1798 CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY 1857
Query 1860 KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLN 1919
KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL+PTQPLPNASFDNFKLTCSNTKFADDLN
Sbjct 1858 KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLIPTQPLPNASFDNFKLTCSNTKFADDLN 1917
Query 1920 QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT 1979
QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT
Sbjct 1918 QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT 1977
Query 1980 FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVI 2039
FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPT EEVVENPTIQKEVI
Sbjct 1978 FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTPEEVVENPTIQKEVI 2037
Query 2040 ECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTI 2099
ECDVKTTEVVGNVILKPSDEGVKVTQEL HEDLMAAYVENTSITIKKPNELSLALGLKTI
Sbjct 2038 ECDVKTTEVVGNVILKPSDEGVKVTQELDHEDLMAAYVENTSITIKKPNELSLALGLKTI 2097
Query 2100 ATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTF 2159
ATHGIAAINSVPW KILAYVKPFLGQAA+TTSNCAKRL QR+FNNYMPYV TLLFQLCTF
Sbjct 2098 ATHGIAAINSVPWGKILAYVKPFLGQAAVTTSNCAKRLVQRMFNNYMPYVLTLLFQLCTF 2157
Query 2160 TKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS 2219
TKSTNSRIRASLPTTIAKNSV+ + +LCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS
Sbjct 2158 TKSTNSRIRASLPTTIAKNSVRGIVRLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS 2217
Query 2220 LICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYP 2279
LI VTAA GVLLSNFGAPSYC+GVRE YLNSSNVTTMDFCEGSFPCS+CLSGLDSLDSYP
Sbjct 2218 LIYVTAALGVLLSNFGAPSYCSGVRESYLNSSNVTTMDFCEGSFPCSVCLSGLDSLDSYP 2277
Query 2280 ALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2339
ALETIQVTISSYKLDLTILGLAAEW AYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS
Sbjct 2278 ALETIQVTISSYKLDLTILGLAAEWFFAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2337
Query 2340 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2399
WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE
Sbjct 2338 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2397
Query 2400 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPIN 2459
CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFC GSTFISDEVARDLSLQFKRPIN
Sbjct 2398 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCAGSTFISDEVARDLSLQFKRPIN 2457
Query 2460 PTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2519
PTDQSSY+VDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV
Sbjct 2458 PTDQSSYVVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2517
Query 2520 FDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2579
FDGKSKCDESA+KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF
Sbjct 2518 FDGKSKCDESAAKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2577
Query 2580 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD 2639
SVPMEKLKALVATAHSELAKGVALDGVLSTFVSA+RQGVVDTDVDTKDVIECLKLSHHSD
Sbjct 2578 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSASRQGVVDTDVDTKDVIECLKLSHHSD 2637
Query 2640 LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLS 2699
LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVA+SHNVSLIWNVKDYMSLS
Sbjct 2638 LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVARSHNVSLIWNVKDYMSLS 2697
Query 2700 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVL 2759
EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVST FK+MLKATLLCVL
Sbjct 2698 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTWFKIMLKATLLCVL 2757
Query 2760 AALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRG 2819
AALVCYIVMPVH LS+H GYTNEIIGYKAIQDGVTRDI+STDDCFANKHAGFD+WFSQRG
Sbjct 2758 AALVCYIVMPVHILSVHGGYTNEIIGYKAIQDGVTRDIVSTDDCFANKHAGFDSWFSQRG 2817
Query 2820 GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL
Sbjct 2818 GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2877
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2939
IEYSDF+TSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII
Sbjct 2878 IEYSDFSTSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2937
Query 2940 QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVD 2999
QFPN YLEGSVRVVTTFDAEYCRHGTCERSE GICLSTSGRWVLNNEHYRAL GVFCGVD
Sbjct 2938 QFPNAYLEGSVRVVTTFDAEYCRHGTCERSEAGICLSTSGRWVLNNEHYRALPGVFCGVD 2997
Query 3000 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANA 3059
AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRR FGEYNHVVAANA
Sbjct 2998 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRAFGEYNHVVAANA 3057
Query 3060 LLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3119
LFLMSFTILCL PAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA
Sbjct 3058 PLFLMSFTILCLAPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3117
Query 3120 IYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3179
IYVFCISLKH HWFFNNYLRKRV+FNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT
Sbjct 3118 IYVFCISLKHFHWFFNNYLRKRVVFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3177
Query 3180 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3239
QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL
Sbjct 3178 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3237
Query 3240 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI 3299
QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI
Sbjct 3238 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI 3297
Query 3300 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3359
RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN
Sbjct 3298 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3357
Query 3360 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3419
GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT VHAGTDLEG
Sbjct 3358 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTEVHAGTDLEG 3417
Query 3420 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3479
KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY
Sbjct 3418 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3477
Query 3480 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3539
EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ
Sbjct 3478 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3537
Query 3540 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIA 3599
CSGVTFQGKFK+IVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA+A
Sbjct 3538 CSGVTFQGKFKRIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAVA 3597
Query 3600 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3659
ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC
Sbjct 3598 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3657
Query 3660 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3719
VMYASALVLL+LMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS
Sbjct 3658 VMYASALVLLVLMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3717
Query 3720 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3779
NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR
Sbjct 3718 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3777
Query 3780 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3839
YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM
Sbjct 3778 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3837
Query 3840 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3899
SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ
Sbjct 3838 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3897
Query 3900 GAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3959
GAVDIN+LCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK
Sbjct 3898 GAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3957
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
SLNVAKSEFDR+AAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN
Sbjct 3958 SLNVAKSEFDRNAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4017
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV
Sbjct 4018 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4077
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4139
DADSKIVQLSEINM+NS NLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA
Sbjct 4078 DADSKIVQLSEINMENSSNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4137
Query 4140 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4199
CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG
Sbjct 4138 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4197
Query 4200 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4259
PKVKYL+FIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD
Sbjct 4198 PKVKYLHFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4257
Query 4260 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4319
YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF
Sbjct 4258 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4317
Query 4320 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP+MQSADASTFLNR
Sbjct 4318 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPMMQSADASTFLNR 4377
Query 4380 VCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF 4439
VCGVSAARLTPCGTG STDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF
Sbjct 4378 VCGVSAARLTPCGTGISTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF 4437
Query 4440 VVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA 4499
VVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA
Sbjct 4438 VVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA 4497
Query 4500 LRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTV 4559
LRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQ+LLKTV
Sbjct 4498 LRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTV 4557
Query 4560 QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRA 4619
QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRA
Sbjct 4558 QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRA 4617
Query 4620 LAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHC 4679
LAAESHMDADLAKPLIKWDLLKYDFT ERLCLFDRYFKYWDQTYHPNCINCLDDRCILHC
Sbjct 4618 LAAESHMDADLAKPLIKWDLLKYDFTAERLCLFDRYFKYWDQTYHPNCINCLDDRCILHC 4677
Query 4680 ANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKE 4739
ANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKE
Sbjct 4678 ANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKE 4737
Query 4740 LLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFK 4799
LLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFK
Sbjct 4738 LLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFK 4797
Query 4800 EGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA 4859
EGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA
Sbjct 4798 EGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA 4857
Query 4860 NQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISA 4919
NQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISA
Sbjct 4858 NQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISA 4917
Query 4920 KNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE 4979
KNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE
Sbjct 4918 KNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE 4977
Query 4980 TPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCG 5039
TPHLMGWDYPKCDRAMPNMLRIMASLVLARKH+TCCNLSHRFYRLANECAQVLSEMVMCG
Sbjct 4978 TPHLMGWDYPKCDRAMPNMLRIMASLVLARKHSTCCNLSHRFYRLANECAQVLSEMVMCG 5037
Query 5040 GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYEC 5099
GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYEC
Sbjct 5038 GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYEC 5097
Query 5100 LYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQN 5159
LYRNRDVDHEFV EFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQN
Sbjct 5098 LYRNRDVDHEFVGEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQN 5157
Query 5160 NVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKT 5219
NVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKT
Sbjct 5158 NVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKT 5217
Query 5220 DGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTND 5279
DGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTND
Sbjct 5218 DGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTND 5277
Query 5280 NTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTS 5339
NTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTS
Sbjct 5278 NTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTS 5337
Query 5340 HKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCV 5399
HKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCV
Sbjct 5338 HKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCV 5397
Query 5400 GSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVL 5459
GSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVL
Sbjct 5398 GSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVL 5457
Query 5460 SDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYK 5519
SDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYK
Sbjct 5458 SDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYK 5517
Query 5520 LNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYS 5579
LN+GDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYS
Sbjct 5518 LNIGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYS 5577
Query 5580 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA 5639
TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA
Sbjct 5578 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA 5637
Query 5640 RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY 5699
RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY
Sbjct 5638 RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY 5697
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD
Sbjct 5698 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5757
Query 5760 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5819
NKLKAHK+KSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ
Sbjct 5758 NKLKAHKEKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5817
Query 5820 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD 5879
NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD
Sbjct 5818 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD 5877
Query 5880 RDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEG 5939
RDLYDKLQFTSLE+PRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVD KFKTEG
Sbjct 5878 RDLYDKLQFTSLEVPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDTKFKTEG 5937
Query 5940 LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHAT 5999
LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHAT
Sbjct 5938 LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHAT 5997
Query 6000 RDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGL 6059
RDAVGTNLPLQLGFSTGVNLVA+PTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGL
Sbjct 5998 RDAVGTNLPLQLGFSTGVNLVAIPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGL 6057
Query 6060 PWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCF 6119
PWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCF
Sbjct 6058 PWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCF 6117
Query 6120 STSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMT 6179
STSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMT
Sbjct 6118 STSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMT 6177
Query 6180 RCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKA 6239
RCLAVHECFVKRVDWSVEYPIIGDEL++NSACRKVQHMVVKSALLADKFPVLHDIGNPKA
Sbjct 6178 RCLAVHECFVKRVDWSVEYPIIGDELKINSACRKVQHMVVKSALLADKFPVLHDIGNPKA 6237
Query 6240 IKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAI 6299
IKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAI
Sbjct 6238 IKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAI 6297
Query 6300 VCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGK 6359
VCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGK
Sbjct 6298 VCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGK 6357
Query 6360 QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTY 6419
QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTY
Sbjct 6358 QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTY 6417
Query 6420 NLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLP 6479
NLWNTFTRLQSLENVAYNVVNKGHFDG AGE PVSIINNAVYTKVDG DVEIFENKTTLP
Sbjct 6418 NLWNTFTRLQSLENVAYNVVNKGHFDGQAGETPVSIINNAVYTKVDGFDVEIFENKTTLP 6477
Query 6480 VNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKK 6539
VNVAFELWAKRNIK VPEIKILNNLGVDIAANTVIWD+KREAP H+STIGVCTMTDIAKK
Sbjct 6478 VNVAFELWAKRNIKSVPEIKILNNLGVDIAANTVIWDHKREAPVHMSTIGVCTMTDIAKK 6537
Query 6540 PTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGE 6599
PTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGE
Sbjct 6538 PTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGE 6597
Query 6600 SVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGY 6659
SVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGY
Sbjct 6598 SVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGY 6657
Query 6660 AFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKC 6719
AFEHIVYGDFSHGQLGGLHLMIGLAKRS+DSPLKLEDFIPMDSTVKNYFITDAQTGSSKC
Sbjct 6658 AFEHIVYGDFSHGQLGGLHLMIGLAKRSRDSPLKLEDFIPMDSTVKNYFITDAQTGSSKC 6717
Query 6720 VCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQA 6779
VCSVIDLLLDDFVEIIKSQDLSV+SKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQA
Sbjct 6718 VCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQA 6777
Query 6780 WQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYN 6839
WQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYN
Sbjct 6778 WQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYN 6837
Query 6840 MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW 6899
MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW
Sbjct 6838 MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW 6897
Query 6900 DLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLM 6959
DLI+SDMYDP+ KHVTKENDSKEGFFTYLCGFIKQKLALGGS+AVKITEHSWNADLYKLM
Sbjct 6898 DLIVSDMYDPKAKHVTKENDSKEGFFTYLCGFIKQKLALGGSVAVKITEHSWNADLYKLM 6957
Query 6960 GHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSL 7019
GHFSWWTAFVTNVNASSSEAFLIG NYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSL
Sbjct 6958 GHFSWWTAFVTNVNASSSEAFLIGVNYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSL 7017
Query 7020 FDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
FDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN
Sbjct 7018 FDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7071
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 14167 bits (36767), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 6768/7074 (96%), Positives = 6937/7074 (98%), Gaps = 8/7074 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDALSTNHGHKVVELVAE+DGIQ+GRSGITLGVLVPHVGETPIAYRN
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAELDGIQFGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHS+GIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
VTRYVDNNFCGPDGYPL+CIKDFLARAGKSMCTLSEQLDYIESKRGVYCCR+HEHEI W
Sbjct 181 VVTRYVDNNFCGPDGYPLECIKDFLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERS+KSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSEKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVA+PQECN+MHLSTLMKCNHCDEVSWQTCDFLKATCE CGTENLV EGPTTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
PTNAVVKMPCPACQDPE+GPEHSVADYHNHSNIETRLRKGGRT+CFGGCVF+YVGCYNKR
Sbjct 361 PTNAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFSYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASA+IG+ HTGITG+NVETLNEDLLEIL+RERVNINIVGDF NEEVAIILASF
Sbjct 421 AYWVPRASANIGANHTGITGENVETLNEDLLEILNRERVNINIVGDFRFNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SAS SAFI+T+K LDYKSFK IVESCGNYKVT GKPV GAWNIGQQRS+LTPLCGFPSQA
Sbjct 481 SASPSAFIETVKGLDYKSFKVIVESCGNYKVTNGKPVTGAWNIGQQRSILTPLCGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIF+RTLDAANHSI DLQRAAVT LDGISEQSLRLVDAMVYTSDLLTNSV++MAY
Sbjct 541 AGVIRSIFSRTLDAANHSILDLQRAAVTTLDGISEQSLRLVDAMVYTSDLLTNSVVVMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQT QWLSN+LGT V+KL+P+F W+EAKLSAGVEFL+DAWEILKFLITGVFD++
Sbjct 601 VTGGLVQQTMQWLSNMLGTAVDKLKPVFTWVEAKLSAGVEFLRDAWEILKFLITGVFDVI 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVA+DNIK+CVK F+ VVNKALEMC+DQVTIAG KLR+LNLGEVFIAQS+GLYRQC
Sbjct 661 KGQIQVATDNIKECVKIFLGVVNKALEMCLDQVTIAGTKLRALNLGEVFIAQSRGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPLKAPKEVTFLEGD+HDTVLTSEEVVLK+GELEALETP+DSFT+GA+VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDAHDTVLTSEEVVLKSGELEALETPIDSFTSGAVVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVC+NGLMLLE+++KEQYCALSPGLLATNNVFRLKGGAP+KGVTFGEDTV EVQGYKNV
Sbjct 781 TPVCINGLMLLELENKEQYCALSPGLLATNNVFRLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
+ITFELD RVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLT MGIDLDE
Sbjct 841 KITFELDVRVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTPMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
WSVATFYLFDDAGEE SSRMYCSFYPPDEEE+ + +EEE E EYGTEDDY+GL
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEECEDEEETCEH---EYGTEDDYKGL 957
Query 961 PLEFGASAETVRVEEEEEE-DWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
PLEFGAS ET VEEEEEE DWLDD E PEEPVNQF GYLKLTDNVAIK
Sbjct 958 PLEFGASTETPHVEEEEEEEDWLDDAIEAEPEPEP---LPEEPVNQFVGYLKLTDNVAIK 1014
Query 1020 CVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGG 1079
C+DIVKEAQSA P VIVNAAN HLKHGGGVAGALNKATNGAMQ ESD+YI+ NGPLTVGG
Sbjct 1015 CIDIVKEAQSAKPTVIVNAANTHLKHGGGVAGALNKATNGAMQNESDEYIRQNGPLTVGG 1074
Query 1080 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1139
SCLLSGHNLA+KCLHVVGPNLNAGED+QLLK AYENFNSQD+LLAPLLSAGIFGAKPLQS
Sbjct 1075 SCLLSGHNLAEKCLHVVGPNLNAGEDVQLLKRAYENFNSQDVLLAPLLSAGIFGAKPLQS 1134
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQ 1199
L++CV+ VRTQVY+AVNDK+LY+Q+V+DYLD+LKP+VE+P +EE P E+ K + V +
Sbjct 1135 LKMCVEIVRTQVYLAVNDKSLYDQIVLDYLDSLKPKVESPNKEEEPKLEEPKAVQ-PVAE 1193
Query 1200 KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDA 1259
KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLY DSQNMLRGEDMSFLEKDA
Sbjct 1194 KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYQDSQNMLRGEDMSFLEKDA 1253
Query 1260 PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAK 1319
PY+VGDVITSGDITCV+IP+KK+GGTTEML+RALK+VPV EYITTYPGQGCAGYTLEEAK
Sbjct 1254 PYIVGDVITSGDITCVIIPAKKSGGTTEMLARALKEVPVAEYITTYPGQGCAGYTLEEAK 1313
Query 1320 TALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQ 1379
TALKKCKSAFYVLPSE PN KEE+LGTVSWNLREMLAHAEETRKLMPIC+DVRAIMATIQ
Sbjct 1314 TALKKCKSAFYVLPSETPNEKEEVLGTVSWNLREMLAHAEETRKLMPICLDVRAIMATIQ 1373
Query 1380 RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA 1439
RKYKGIK+QEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHG NLEEAA
Sbjct 1374 RKYKGIKVQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGLNLEEAA 1433
Query 1440 RCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTEL 1499
RCMRSLKAPAVVSVSSPDAVT YNGYLTSSSKT EE+FVET SLAGSYRDWSYSGQRTEL
Sbjct 1434 RCMRSLKAPAVVSVSSPDAVTAYNGYLTSSSKTPEEYFVETTSLAGSYRDWSYSGQRTEL 1493
Query 1500 GVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQ 1559
GVEFLKRGDKIVYHT SP+EFHLDGEVL LDKLKSLLSLREVKTIKVFTTVDNTNLHT
Sbjct 1494 GVEFLKRGDKIVYHTTGSPIEFHLDGEVLPLDKLKSLLSLREVKTIKVFTTVDNTNLHTH 1553
Query 1560 LVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF 1619
+VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHT+DESF
Sbjct 1554 IVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTIDESF 1613
Query 1620 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRA 1679
LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ+EVKFNAPALQEAYYRA
Sbjct 1614 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQVEVKFNAPALQEAYYRA 1673
Query 1680 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1739
RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL
Sbjct 1674 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1733
Query 1740 TGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL 1799
GVEAVMYMGTLSYD LKTGVSIPCVCGR+ATQYLVQQESSFVMMSAPPAEYKLQQG FL
Sbjct 1734 KGVEAVMYMGTLSYDELKTGVSIPCVCGRNATQYLVQQESSFVMMSAPPAEYKLQQGAFL 1793
Query 1800 CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY 1859
CANEYTGNYQCGHYTHITAKETLYR+DGAHLTKMSEYKGPVTDVFYKETSYTT IKPVSY
Sbjct 1794 CANEYTGNYQCGHYTHITAKETLYRVDGAHLTKMSEYKGPVTDVFYKETSYTTAIKPVSY 1853
Query 1860 KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLN 1919
KLDGVTYTEIEPKLDGYYKK NAYYTEQPIDLVPTQP+PNASFDNFKLTCSNTKFADDLN
Sbjct 1854 KLDGVTYTEIEPKLDGYYKKGNAYYTEQPIDLVPTQPMPNASFDNFKLTCSNTKFADDLN 1913
Query 1920 QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT 1979
QMTGF KPASREL+VTFFPDLNGDVVAIDYRHYS SFKKGAKL+HKPI+WHINQ T KTT
Sbjct 1914 QMTGFKKPASRELTVTFFPDLNGDVVAIDYRHYSTSFKKGAKLVHKPILWHINQTTNKTT 1973
Query 1980 FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVI 2039
+KPN WCLRCLWSTKPVDTSNSFEVL VEDTQGMDNLACESQ TSEEVVENPT+QKE+I
Sbjct 1974 YKPNIWCLRCLWSTKPVDTSNSFEVLVVEDTQGMDNLACESQTTTSEEVVENPTVQKEII 2033
Query 2040 ECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTI 2099
ECDVKTTEVVGNVILKPS+EGVKVTQELGHEDLMAAYVE TSITIKKPNELSLALGLKT+
Sbjct 2034 ECDVKTTEVVGNVILKPSEEGVKVTQELGHEDLMAAYVEETSITIKKPNELSLALGLKTL 2093
Query 2100 ATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTF 2159
ATHG AAINSVPWSKILAYVKPFLGQ A+ TSNC K+ QRVF+NYMPYV TLLFQLCTF
Sbjct 2094 ATHGAAAINSVPWSKILAYVKPFLGQTAVITSNCIKKCVQRVFSNYMPYVITLLFQLCTF 2153
Query 2160 TKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS 2219
TKSTNSRI+ASLPTTIAKNSVKSVAKLCLD INYVKSPKFSKLFTI MWLLLLSICLGS
Sbjct 2154 TKSTNSRIKASLPTTIAKNSVKSVAKLCLDVCINYVKSPKFSKLFTIVMWLLLLSICLGS 2213
Query 2220 LICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYP 2279
L VTA GV LS+ G PSYC+GVRELY+NSSNVTTMDFC+G FPCS+CLSGLDSLDSYP
Sbjct 2214 LTYVTAVLGVCLSSLGVPSYCDGVRELYINSSNVTTMDFCQGYFPCSVCLSGLDSLDSYP 2273
Query 2280 ALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2339
ALETIQVTISSYKLDLT LGLAAEW+LAYMLFTKFFYLLGLSAIMQ FFGYFASHFISNS
Sbjct 2274 ALETIQVTISSYKLDLTFLGLAAEWLLAYMLFTKFFYLLGLSAIMQAFFGYFASHFISNS 2333
Query 2340 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2399
WLMWFIISIVQMAPVSAMVRMYIFFASFYY+WKSYVHIMDGCTSSTCMMCYKRNRATRVE
Sbjct 2334 WLMWFIISIVQMAPVSAMVRMYIFFASFYYVWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2393
Query 2400 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPIN 2459
CTTIVNG+KRSFYVYANGGRGFCK HNWNCLNCDTFC GSTFISDEVARDLSLQFKRPIN
Sbjct 2394 CTTIVNGVKRSFYVYANGGRGFCKAHNWNCLNCDTFCAGSTFISDEVARDLSLQFKRPIN 2453
Query 2460 PTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2519
PTDQS+Y+VDSV VKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV
Sbjct 2454 PTDQSAYVVDSVTVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2513
Query 2520 FDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2579
FDGKSKC+ESA+KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF
Sbjct 2514 FDGKSKCEESAAKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2573
Query 2580 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD 2639
SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD
Sbjct 2574 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD 2633
Query 2640 LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLS 2699
+EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSL+WNVKDYMSLS
Sbjct 2634 IEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLVWNVKDYMSLS 2693
Query 2700 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVL 2759
EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGK+VST FKL+LK TLLCVL
Sbjct 2694 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKVVSTWFKLLLKVTLLCVL 2753
Query 2760 AALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRG 2819
AAL CY++MPVH+LS+HDGYTNEIIGYKAIQDGVTRDI+STDDCFANKHAGFD+WFSQRG
Sbjct 2754 AALFCYVIMPVHSLSVHDGYTNEIIGYKAIQDGVTRDIVSTDDCFANKHAGFDSWFSQRG 2813
Query 2820 GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
GSY+NDK+CPVVAAIITREIGFIVPGLPGTVLRA+NGDFLHFLPRVFSAVGNICYTPSKL
Sbjct 2814 GSYRNDKNCPVVAAIITREIGFIVPGLPGTVLRALNGDFLHFLPRVFSAVGNICYTPSKL 2873
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2939
IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII
Sbjct 2874 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2933
Query 2940 QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVD 2999
QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVG+CLSTSGRWVLNNEHYRAL GVFCGVD
Sbjct 2934 QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGVCLSTSGRWVLNNEHYRALPGVFCGVD 2993
Query 3000 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANA 3059
AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRR FGEYNHVVAANA
Sbjct 2994 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRAFGEYNHVVAANA 3053
Query 3060 LLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3119
LLFLMSFTILCL PAYSFLPGVYS+FYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA
Sbjct 3054 LLFLMSFTILCLAPAYSFLPGVYSIFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3113
Query 3120 IYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3179
IYVFCISLKH HWFF+NYL+KRVMFNGVTFSTFEEAALCTFLLNKEMYL+LRSETLLPLT
Sbjct 3114 IYVFCISLKHFHWFFSNYLKKRVMFNGVTFSTFEEAALCTFLLNKEMYLRLRSETLLPLT 3173
Query 3180 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3239
QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL
Sbjct 3174 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3233
Query 3240 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI 3299
QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHV+CTAEDMLNPNY+DLLI
Sbjct 3234 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVVCTAEDMLNPNYDDLLI 3293
Query 3300 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3359
RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN
Sbjct 3294 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3353
Query 3360 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3419
GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3354 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3413
Query 3420 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3479
KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY
Sbjct 3414 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3473
Query 3480 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3539
EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ
Sbjct 3474 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3533
Query 3540 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIA 3599
CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPF LGIMA+A
Sbjct 3534 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFALGIMAVA 3593
Query 3600 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3659
ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC
Sbjct 3594 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3653
Query 3660 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3719
VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGN+LDQAISMWALVISVTS
Sbjct 3654 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAISMWALVISVTS 3713
Query 3720 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3779
NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR
Sbjct 3714 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3773
Query 3780 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3839
YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM
Sbjct 3774 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3833
Query 3840 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3899
SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ
Sbjct 3834 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3893
Query 3900 GAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3959
GAVDIN+LCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAV+NGDSEVVLKKLKK
Sbjct 3894 GAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVSNGDSEVVLKKLKK 3953
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
SLNVAKSEFD DAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN
Sbjct 3954 SLNVAKSEFDHDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4013
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV
Sbjct 4014 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4073
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4139
DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA
Sbjct 4074 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4133
Query 4140 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4199
CTDDNALAYYNN+KGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG
Sbjct 4134 CTDDNALAYYNNAKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4193
Query 4200 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4259
PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD
Sbjct 4194 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4253
Query 4260 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4319
YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF
Sbjct 4254 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4313
Query 4320 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP+MQSADASTFLNR
Sbjct 4314 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPMMQSADASTFLNR 4373
Query 4380 VCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF 4439
VCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF
Sbjct 4374 VCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF 4433
Query 4440 VVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA 4499
VVKRHTMSNYQHEETIYNL+K+CPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA
Sbjct 4434 VVKRHTMSNYQHEETIYNLIKECPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA 4493
Query 4500 LRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTV 4559
LRHFDEGNCDTLKEILVTYNCCDD+YFNKKDWYDFVENPD+LRVYANLGERVR++LLKTV
Sbjct 4494 LRHFDEGNCDTLKEILVTYNCCDDNYFNKKDWYDFVENPDVLRVYANLGERVRRALLKTV 4553
Query 4560 QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRA 4619
QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLT+A
Sbjct 4554 QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTKA 4613
Query 4620 LAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHC 4679
LAAESHMDADLAKPL+KWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHC
Sbjct 4614 LAAESHMDADLAKPLVKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHC 4673
Query 4680 ANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKE 4739
ANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKE
Sbjct 4674 ANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKE 4733
Query 4740 LLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFK 4799
LLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFK
Sbjct 4734 LLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFK 4793
Query 4800 EGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA 4859
EGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA
Sbjct 4794 EGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA 4853
Query 4860 NQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISA 4919
NQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISA
Sbjct 4854 NQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISA 4913
Query 4920 KNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE 4979
KNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE
Sbjct 4914 KNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE 4973
Query 4980 TPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCG 5039
+PHLMGWDYPKCDRAMPNMLRIMASL+LARKH+TCCNLSHRFYRLANECAQVLSEMVMCG
Sbjct 4974 SPHLMGWDYPKCDRAMPNMLRIMASLILARKHSTCCNLSHRFYRLANECAQVLSEMVMCG 5033
Query 5040 GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYEC 5099
GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYEC
Sbjct 5034 GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYEC 5093
Query 5100 LYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQN 5159
LYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQN
Sbjct 5094 LYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQN 5153
Query 5160 NVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKT 5219
NVFMSEAKCWTETDLT+GPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKT
Sbjct 5154 NVFMSEAKCWTETDLTRGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKT 5213
Query 5220 DGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTND 5279
DGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTND
Sbjct 5214 DGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTND 5273
Query 5280 NTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTS 5339
NTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTS
Sbjct 5274 NTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTS 5333
Query 5340 HKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCV 5399
HKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCV
Sbjct 5334 HKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCV 5393
Query 5400 GSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVL 5459
GSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVL
Sbjct 5394 GSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVL 5453
Query 5460 SDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYK 5519
SDREL+LSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYK
Sbjct 5454 SDRELYLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYK 5513
Query 5520 LNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYS 5579
LNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNIS+EFSSNVANYQK+GMQKYS
Sbjct 5514 LNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISNEFSSNVANYQKIGMQKYS 5573
Query 5580 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA 5639
TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA
Sbjct 5574 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA 5633
Query 5640 RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY 5699
RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY
Sbjct 5634 RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY 5693
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD
Sbjct 5694 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5753
Query 5760 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5819
NKLKAHK+KSAQCFKM+YKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ
Sbjct 5754 NKLKAHKEKSAQCFKMYYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5813
Query 5820 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD 5879
NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD
Sbjct 5814 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD 5873
Query 5880 RDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEG 5939
RDLYDKLQFTSLE+PRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVD KFKTEG
Sbjct 5874 RDLYDKLQFTSLEVPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDTKFKTEG 5933
Query 5940 LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHAT 5999
LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHAT
Sbjct 5934 LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHAT 5993
Query 6000 RDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGL 6059
RDAVGTNLPLQLGFSTGVNLVAVPTGYVDTEN+TEFTRVNAKPPPGDQFKHLIPLMYKGL
Sbjct 5994 RDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENSTEFTRVNAKPPPGDQFKHLIPLMYKGL 6053
Query 6060 PWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCF 6119
PWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCF
Sbjct 6054 PWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCF 6113
Query 6120 STSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMT 6179
STSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMT
Sbjct 6114 STSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMT 6173
Query 6180 RCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKA 6239
RCLAVHECFVKRVDWSVEYPIIGDEL++N+ACRKVQHMVVKSALLADKF VLHDIGNPKA
Sbjct 6174 RCLAVHECFVKRVDWSVEYPIIGDELKINAACRKVQHMVVKSALLADKFTVLHDIGNPKA 6233
Query 6240 IKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAI 6299
I+CVPQAEV+WKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAI
Sbjct 6234 IRCVPQAEVDWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAI 6293
Query 6300 VCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGK 6359
VCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFT+LKQLPFFYYSDSPCESHGK
Sbjct 6294 VCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTHLKQLPFFYYSDSPCESHGK 6353
Query 6360 QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTY 6419
QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTY
Sbjct 6354 QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTY 6413
Query 6420 NLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLP 6479
NLWNTFT+LQSLENVAYNVVNKGHFDG +GEAPVSIINNAVYTKVDGIDVEIFENKTTLP
Sbjct 6414 NLWNTFTKLQSLENVAYNVVNKGHFDGQSGEAPVSIINNAVYTKVDGIDVEIFENKTTLP 6473
Query 6480 VNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKK 6539
VNVAFELWAKRNIKPVPEIKILNNLGVDIAAN VIWDYKREAPAHVSTIGVCTMTDIAKK
Sbjct 6474 VNVAFELWAKRNIKPVPEIKILNNLGVDIAANNVIWDYKREAPAHVSTIGVCTMTDIAKK 6533
Query 6540 PTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGE 6599
PTESACSSL VLFDGRVEGQVD FRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGE
Sbjct 6534 PTESACSSLIVLFDGRVEGQVDFFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGE 6593
Query 6600 SVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGY 6659
SVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGY
Sbjct 6594 SVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGY 6653
Query 6660 AFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKC 6719
AFEHIVYGDFSHGQLGGLHLMIGLAKRSQDS LKLEDFIPMDSTVKNYFITDAQTGSSKC
Sbjct 6654 AFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSLLKLEDFIPMDSTVKNYFITDAQTGSSKC 6713
Query 6720 VCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQA 6779
VCSVIDLLLDDFVEIIKSQDLSV+SKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQA
Sbjct 6714 VCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQA 6773
Query 6780 WQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYN 6839
WQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYN
Sbjct 6774 WQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYN 6833
Query 6840 MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW 6899
MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW
Sbjct 6834 MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW 6893
Query 6900 DLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLM 6959
DLIISDMYDP+TKHV K+NDSKEGFFTYLCGFIKQKLALGGS+AVKITEHSWNADLYKLM
Sbjct 6894 DLIISDMYDPKTKHVLKDNDSKEGFFTYLCGFIKQKLALGGSVAVKITEHSWNADLYKLM 6953
Query 6960 GHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSL 7019
GHFSWWTAFVTNVNASSSEAFLIG NYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSL
Sbjct 6954 GHFSWWTAFVTNVNASSSEAFLIGVNYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSL 7013
Query 7020 FDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
FDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN
Sbjct 7014 FDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7067
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 14123 bits (36653), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 6757/7084 (95%), Positives = 6917/7084 (98%), Gaps = 16/7084 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESL LGV+EKTHVQLSLPVLQVRDVLVRGFGDSVEEAL+EAREHLKNGTCGLVELEKGV
Sbjct 1 MESLALGVSEKTHVQLSLPVLQVRDVLVRGFGDSVEEALAEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDA TNHG+KVVELVAE+DGIQYGRSG TLGVLVPHVGETP+AYRN
Sbjct 61 LPQLEQPYVFIKRSDAQGTNHGYKVVELVAELDGIQYGRSGTTLGVLVPHVGETPVAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHSYGIDLKSYDLG ELGTDPIEDYEQNWNTKHG G LREL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGVELGTDPIEDYEQNWNTKHGGGVLRELIRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGKSMCTLSEQLDYIESKRGVYCCR+HEHEI W
Sbjct 181 AFTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERS+KSYE QTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSEKSYERQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVA+PQECN+MHLSTLMKCNHCDEVSWQTCDFLKATCE CGTENLV EGPTTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
P NAVVKMPCPACQDPE+GPEHSVADYHNHSNIETRLRKGGRT+CFGGCVFAYVGCYNKR
Sbjct 361 PANAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASA+IG+ HTGITGDNVETLNEDL+EIL+R+RVNINIVGDFHLNEEVAIILASF
Sbjct 421 AYWVPRASANIGASHTGITGDNVETLNEDLMEILNRDRVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SAST AF+DT+K LDYK+FK IVESCGN+KVT+G+ KGAWNIGQ++S+LTPL GFPSQA
Sbjct 481 SASTCAFVDTVKGLDYKTFKDIVESCGNFKVTRGRAKKGAWNIGQEKSILTPLYGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIF R LD ANHSIPDLQRAA+TILDGISEQSLRL+DAMVYTSDLLTNSVI+MAY
Sbjct 541 AGVIRSIFTRALDTANHSIPDLQRAAITILDGISEQSLRLIDAMVYTSDLLTNSVIVMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQ +QWLSN+LGTTV+KL+P+F W+EAKLSAG+EFL+DAWEILKFL+TGVFDIV
Sbjct 601 VTGGLVQQITQWLSNMLGTTVDKLKPVFTWVEAKLSAGIEFLRDAWEILKFLVTGVFDIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVASDN+K+CVK F+DV+NKALEMCIDQV IAGAKLR+LNLGEVFIAQSKGLYRQC
Sbjct 661 KGQIQVASDNLKECVKAFLDVLNKALEMCIDQVIIAGAKLRTLNLGEVFIAQSKGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPL+APKEVTF EGDSHDTV TSEEVVLKNGELEALETPVDSFTNGA++G
Sbjct 721 IRGKEQLQLLMPLRAPKEVTFFEGDSHDTVFTSEEVVLKNGELEALETPVDSFTNGAVIG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVCVNGLMLLE+KDKEQYCALSPGLLATNNVF LKGGAP+KGVTFGEDTV EVQGYKNV
Sbjct 781 TPVCVNGLMLLELKDKEQYCALSPGLLATNNVFSLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
+ITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
Sbjct 841 KITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCE-HEYGTEDDYQG 959
WSVATFYLFDDAGEE SSRMYCSFYPPDEEE+ + +EEEI E HEYGTEDDY+G
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEEYEDEEEIPEETCEHEYGTEDDYKG 960
Query 960 LPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
LPLEFGAS E +++ +EE+ D E +PEPEP PEEPVNQFTGYLKLTDNVAIK
Sbjct 961 LPLEFGASTE---IQQVDEEEEEDWLEEAIAAKPEPEPLPEEPVNQFTGYLKLTDNVAIK 1017
Query 1020 CVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGG 1079
CVDIVKEAQ A P VIVNAAN+HLKHGGGVAGALNKATNGAMQ+ESDDYIK NGPLTVGG
Sbjct 1018 CVDIVKEAQHAKPTVIVNAANVHLKHGGGVAGALNKATNGAMQQESDDYIKKNGPLTVGG 1077
Query 1080 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1139
SCLLSGHNLAKKC+HVVGPNLNAGED+QLLKAAY NFNSQD+LLAPLLSAGIFGAKPLQS
Sbjct 1078 SCLLSGHNLAKKCMHVVGPNLNAGEDVQLLKAAYANFNSQDVLLAPLLSAGIFGAKPLQS 1137
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQE----------EPPNTED 1189
L++CV+TVRTQVY AVND+ LY+ VV+ YLD+LKP+VE P QE E E+
Sbjct 1138 LKMCVETVRTQVYFAVNDQDLYDHVVLGYLDSLKPKVETPTQENLELKEQPAVETLTQEN 1197
Query 1190 SKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRG 1249
+ EE V++KPVDVK KA I+EV T+LEETKFLT++LLLFADINGKLY DSQNMLRG
Sbjct 1198 LELEELPVIEKPVDVK--FKARIEEVNTSLEETKFLTSRLLLFADINGKLYQDSQNMLRG 1255
Query 1250 EDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQG 1309
EDM FLEKDAPY+VGDVI+SGDITCV+IP+KKAGGTTEML++ALKKVPV EYITTYPGQG
Sbjct 1256 EDMFFLEKDAPYIVGDVISSGDITCVIIPAKKAGGTTEMLAKALKKVPVSEYITTYPGQG 1315
Query 1310 CAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICM 1369
CAGYTLEEAKTAL+KCKS FYVLPS+ PN KEEILGTVSWNLREMLAHAEETRKLM ICM
Sbjct 1316 CAGYTLEEAKTALRKCKSVFYVLPSKTPNDKEEILGTVSWNLREMLAHAEETRKLMLICM 1375
Query 1370 DVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYV 1429
DV+A+M+TI R+YKGIK+QEGIVDYGVRFFFYTSKEPVASIITKLN LNEPLVTMPIGYV
Sbjct 1376 DVKALMSTIHRRYKGIKVQEGIVDYGVRFFFYTSKEPVASIITKLNLLNEPLVTMPIGYV 1435
Query 1430 THGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRD 1489
THG NLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHF+ETVSLAG YRD
Sbjct 1436 THGLNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFIETVSLAGMYRD 1495
Query 1490 WSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFT 1549
WSYSGQRTELGVEFLKRGDK+VYHT+ SP++FHLDGEVL LDKLKSLLSLREV+TIKVFT
Sbjct 1496 WSYSGQRTELGVEFLKRGDKVVYHTVGSPIQFHLDGEVLLLDKLKSLLSLREVRTIKVFT 1555
Query 1550 TVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAF 1609
TVDNTNLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH HEGKTFFVLPSDDTLRSEAF
Sbjct 1556 TVDNTNLHTQIVDMSMTYGQQFGPTYLDGADVTKIKPHAKHEGKTFFVLPSDDTLRSEAF 1615
Query 1610 EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNA 1669
EYYHTLDESFLGRYMSALNHTKKWKFPQ+GGLTSIKWADNNCYLSSVLLALQQ+EVKFNA
Sbjct 1616 EYYHTLDESFLGRYMSALNHTKKWKFPQIGGLTSIKWADNNCYLSSVLLALQQIEVKFNA 1675
Query 1670 PALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVC 1729
PALQEAYYRARAGDAANFCALILAYSN+TVGELGDVRETMTHLLQHANLESAKRVLNVVC
Sbjct 1676 PALQEAYYRARAGDAANFCALILAYSNRTVGELGDVRETMTHLLQHANLESAKRVLNVVC 1735
Query 1730 KHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPA 1789
K CGQK+TTLTGVEAVMYMGTLSY+ LKTGV+IPC+CGRDATQYLVQQESSFVMMSAPP+
Sbjct 1736 KTCGQKSTTLTGVEAVMYMGTLSYEELKTGVTIPCICGRDATQYLVQQESSFVMMSAPPS 1795
Query 1790 EYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETS 1849
EY LQQG FLCANEYTG+YQCGHYTH+T KETLYRIDGA+LTKMSEYKGPVTDVFYKE S
Sbjct 1796 EYTLQQGAFLCANEYTGSYQCGHYTHVTVKETLYRIDGAYLTKMSEYKGPVTDVFYKEIS 1855
Query 1850 YTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTC 1909
YTTTIKPVSYKLDGV YTEI+PKLD YYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTC
Sbjct 1856 YTTTIKPVSYKLDGVIYTEIQPKLDEYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTC 1915
Query 1910 SNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVW 1969
SNTKFADDLNQMTGF KPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPI+W
Sbjct 1916 SNTKFADDLNQMTGFKKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIIW 1975
Query 1970 HINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVV 2029
HINQ T KTT+KPNTWCLRCLWSTKPV+TSNSFEVL VEDTQGMDNLACESQ PTSEEVV
Sbjct 1976 HINQTTNKTTYKPNTWCLRCLWSTKPVETSNSFEVLEVEDTQGMDNLACESQTPTSEEVV 2035
Query 2030 ENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNE 2089
ENPTIQKEVIECDVKT EVVGNVILKPS+EGVKVTQELGHEDLMAAYVE TSITIKKPNE
Sbjct 2036 ENPTIQKEVIECDVKTIEVVGNVILKPSEEGVKVTQELGHEDLMAAYVEETSITIKKPNE 2095
Query 2090 LSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYV 2149
LSLALGL+T+ATHG AAINSVPWSKILAYVKPFLGQAA+TT+NC KR QRVFNNYMPYV
Sbjct 2096 LSLALGLRTLATHGAAAINSVPWSKILAYVKPFLGQAAVTTTNCIKRCVQRVFNNYMPYV 2155
Query 2150 FTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMW 2209
TLLFQLCTFT+STNSRIRASLPTTIAKNSVKSVAKLCLD INYVKSPKFSKLFTIAMW
Sbjct 2156 ITLLFQLCTFTRSTNSRIRASLPTTIAKNSVKSVAKLCLDVCINYVKSPKFSKLFTIAMW 2215
Query 2210 LLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICL 2269
LLLLSICLGSLI VTAAFGVLLSN G PSYC+GVRE Y+NSSNVTTMDFCEGSF CS+CL
Sbjct 2216 LLLLSICLGSLIYVTAAFGVLLSNLGIPSYCDGVRESYVNSSNVTTMDFCEGSFLCSVCL 2275
Query 2270 SGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFG 2329
+GLDSLDSYPALETIQVTISSYKLDLT LGLAAEW LAYMLFTKFFYLLGLSAIMQVFFG
Sbjct 2276 NGLDSLDSYPALETIQVTISSYKLDLTSLGLAAEWFLAYMLFTKFFYLLGLSAIMQVFFG 2335
Query 2330 YFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMC 2389
YFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFA YY+WKSYVHIMDGCTSSTCMMC
Sbjct 2336 YFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFAFCYYVWKSYVHIMDGCTSSTCMMC 2395
Query 2390 YKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARD 2449
YKRNRATRVECTTIVNGMKRSFYVYANGGRGFCK HNWNCLNCDTFC GSTFISDEVARD
Sbjct 2396 YKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKAHNWNCLNCDTFCAGSTFISDEVARD 2455
Query 2450 LSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNT 2509
LSLQFKRPINPTDQSSY+VDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNT
Sbjct 2456 LSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNT 2515
Query 2510 KGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFD 2569
KGSLPINVIVFDGKSKCDESA+KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFD
Sbjct 2516 KGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFD 2575
Query 2570 AYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVI 2629
AYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVI
Sbjct 2576 AYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVI 2635
Query 2630 ECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLI 2689
ECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLI
Sbjct 2636 ECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLI 2695
Query 2690 WNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKL 2749
WNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVN ITTKISLKGGKIVST FKL
Sbjct 2696 WNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNAITTKISLKGGKIVSTWFKL 2755
Query 2750 MLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHA 2809
MLKATLLCVLAAL CYI+MPVH+LS+HDGYTNEIIGYKAIQDGVTRDI++TDDCFANKHA
Sbjct 2756 MLKATLLCVLAALFCYIIMPVHSLSVHDGYTNEIIGYKAIQDGVTRDIMATDDCFANKHA 2815
Query 2810 GFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAV 2869
GFD+WFSQRGGSY+NDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAV
Sbjct 2816 GFDSWFSQRGGSYRNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAV 2875
Query 2870 GNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDT 2929
GNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDT
Sbjct 2876 GNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDT 2935
Query 2930 RYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYR 2989
RYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE G+CLSTSGRWVLNNEHYR
Sbjct 2936 RYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEAGVCLSTSGRWVLNNEHYR 2995
Query 2990 ALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFG 3049
AL GVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRR FG
Sbjct 2996 ALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRAFG 3055
Query 3050 EYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMF 3109
EYNHVVAANALLFLMSFTILCL PAYSFLPGVYS+FYLYLTFYFTNDVSFLAHLQWFAMF
Sbjct 3056 EYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYLYLTFYFTNDVSFLAHLQWFAMF 3115
Query 3110 SPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLK 3169
SPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLK
Sbjct 3116 SPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLK 3175
Query 3170 LRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQP 3229
LRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQP
Sbjct 3176 LRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQP 3235
Query 3230 PQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDM 3289
PQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDM
Sbjct 3236 PQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDM 3295
Query 3290 LNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPG 3349
LNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPG
Sbjct 3296 LNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPG 3355
Query 3350 QTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT 3409
QTFSVLACYNGSPSGVYQCAMRPN+TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT
Sbjct 3356 QTFSVLACYNGSPSGVYQCAMRPNYTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT 3415
Query 3410 GVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLND 3469
GVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLND
Sbjct 3416 GVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLND 3475
Query 3470 FNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILED 3529
FNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILED
Sbjct 3476 FNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILED 3535
Query 3530 EFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFL 3589
EFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFL
Sbjct 3536 EFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFL 3595
Query 3590 PFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADT 3649
PFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADT
Sbjct 3596 PFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADT 3655
Query 3650 SLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAIS 3709
SLSGYRLKDCVMYASALVLL+LMTARTVYDDAARRVWTLMNVITLVYKVYYGN+LDQAIS
Sbjct 3656 SLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAIS 3715
Query 3710 MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC 3769
MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC
Sbjct 3716 MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC 3775
Query 3770 YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC 3829
YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC
Sbjct 3776 YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC 3835
Query 3830 IKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMV 3889
IKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMV
Sbjct 3836 IKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMV 3895
Query 3890 SLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
SLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD
Sbjct 3896 SLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3955
Query 3950 SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTM 4009
SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTM
Sbjct 3956 SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTM 4015
Query 4010 LFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYA 4069
LFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYA
Sbjct 4016 LFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYA 4075
Query 4070 SALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQM 4129
SALWEIQQVVDADSKIVQLSEINMDNS NLAWPLIVTALRANSAVKLQNNELSPVALRQM
Sbjct 4076 SALWEIQQVVDADSKIVQLSEINMDNSQNLAWPLIVTALRANSAVKLQNNELSPVALRQM 4135
Query 4130 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4189
SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP
Sbjct 4136 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4195
Query 4190 CRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAF 4249
CRFVTDTP+GPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANS VLSFCAF
Sbjct 4196 CRFVTDTPRGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSAVLSFCAF 4255
Query 4250 AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC 4309
AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC
Sbjct 4256 AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC 4315
Query 4310 HIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQ 4369
HIDHPNPKGFCDLKGKYVQIP TCANDPVGFTL+NTVCTVCG WKGYGCSCDQLREP+MQ
Sbjct 4316 HIDHPNPKGFCDLKGKYVQIPATCANDPVGFTLKNTVCTVCGTWKGYGCSCDQLREPMMQ 4375
Query 4370 SADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKD 4429
SADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNE+VAGFAKFLKTNCCRFQEKD
Sbjct 4376 SADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNERVAGFAKFLKTNCCRFQEKD 4435
Query 4430 EEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLT 4489
EEGNLLDSYFVVKRHTMSNYQHEETIYNLVK+CPAVAVHDFFKFRVDGDMVPHISRQRLT
Sbjct 4436 EEGNLLDSYFVVKRHTMSNYQHEETIYNLVKECPAVAVHDFFKFRVDGDMVPHISRQRLT 4495
Query 4490 KYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGE 4549
KYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGE
Sbjct 4496 KYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGE 4555
Query 4550 RVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSL 4609
RVRQ+LLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSL
Sbjct 4556 RVRQALLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSL 4615
Query 4610 LMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCIN 4669
LMPILTLT+ALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCIN
Sbjct 4616 LMPILTLTKALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCIN 4675
Query 4670 CLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVN 4729
CLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVN
Sbjct 4676 CLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVN 4735
Query 4730 LHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFY 4789
LHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFY
Sbjct 4736 LHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFY 4795
Query 4790 DFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF 4849
DFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF
Sbjct 4796 DFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF 4855
Query 4850 DCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTIT 4909
DCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQD LFAYTKRNVIPTIT
Sbjct 4856 DCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDVLFAYTKRNVIPTIT 4915
Query 4910 QMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHN 4969
QMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHN
Sbjct 4916 QMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHN 4975
Query 4970 MLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECA 5029
MLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKH+TCCNLSHRFYRLANECA
Sbjct 4976 MLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHSTCCNLSHRFYRLANECA 5035
Query 5030 QVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV 5089
QVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV
Sbjct 5036 QVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV 5095
Query 5090 RNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIK 5149
RNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIK
Sbjct 5096 RNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIK 5155
Query 5150 NFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGA 5209
NFKAV YYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGA
Sbjct 5156 NFKAVHYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGA 5215
Query 5210 GCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHML 5269
GCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHML
Sbjct 5216 GCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHML 5275
Query 5270 DMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCK 5329
DMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCK
Sbjct 5276 DMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCK 5335
Query 5330 CCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQ 5389
CCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCK HKPPISFPLCANGQ
Sbjct 5336 CCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKLHKPPISFPLCANGQ 5395
Query 5390 VFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLS 5449
VFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLS
Sbjct 5396 VFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLS 5455
Query 5450 YGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDA 5509
YGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDA
Sbjct 5456 YGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDA 5515
Query 5510 VVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVAN 5569
VVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVAN
Sbjct 5516 VVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVAN 5575
Query 5570 YQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID 5629
YQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID
Sbjct 5576 YQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID 5635
Query 5630 KCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVN 5689
KCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVN
Sbjct 5636 KCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVN 5695
Query 5690 ARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEI 5749
ARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEI
Sbjct 5696 ARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEI 5755
Query 5750 VDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRK 5809
VDTVSALVYDNKLKAHK+KSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRK
Sbjct 5756 VDTVSALVYDNKLKAHKEKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRK 5815
Query 5810 AVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRA 5869
AVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRA
Sbjct 5816 AVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRA 5875
Query 5870 KIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHL 5929
KIGILCIMSDRDLYDKLQFTSLE+PRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHL
Sbjct 5876 KIGILCIMSDRDLYDKLQFTSLEVPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHL 5935
Query 5930 SVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWI 5989
SVD KFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWI
Sbjct 5936 SVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWI 5995
Query 5990 GFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFK 6049
GFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFK
Sbjct 5996 GFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFK 6055
Query 6050 HLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTC 6109
HLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTC
Sbjct 6056 HLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTC 6115
Query 6110 CLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNA 6169
CLCD+RATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNA
Sbjct 6116 CLCDRRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNA 6175
Query 6170 HVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFP 6229
HVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDEL++N+ACRKVQHMVVKSALLADKF
Sbjct 6176 HVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELKINAACRKVQHMVVKSALLADKFS 6235
Query 6230 VLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNC 6289
VLHDIGNPKAIKCVPQAEV+WKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNC
Sbjct 6236 VLHDIGNPKAIKCVPQAEVDWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNC 6295
Query 6290 NVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYY 6349
NVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFT LKQLPFFYY
Sbjct 6296 NVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTYLKQLPFFYY 6355
Query 6350 SDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFS 6409
SDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCR HANEYRQYLDAYNMMISAGFS
Sbjct 6356 SDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRRHANEYRQYLDAYNMMISAGFS 6415
Query 6410 LWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDV 6469
LWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDG GEAPVSIINNAVYTKVDG DV
Sbjct 6416 LWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGQIGEAPVSIINNAVYTKVDGNDV 6475
Query 6470 EIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIG 6529
EIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIG
Sbjct 6476 EIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIG 6535
Query 6530 VCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQA 6589
VCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQA
Sbjct 6536 VCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQA 6595
Query 6590 SVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDE 6649
SVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRS+METDFLELAMDE
Sbjct 6596 SVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSKMETDFLELAMDE 6655
Query 6650 FIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFI 6709
FIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIP DSTVKNYFI
Sbjct 6656 FIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPTDSTVKNYFI 6715
Query 6710 TDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVET 6769
TDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVET
Sbjct 6716 TDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVET 6775
Query 6770 FYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYL 6829
FYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYL
Sbjct 6776 FYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYL 6835
Query 6830 NTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGD 6889
NTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTG LLVDSDLNDFVSDADSTLIGD
Sbjct 6836 NTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGALLVDSDLNDFVSDADSTLIGD 6895
Query 6890 CATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEH 6949
CATVHTANKWDLIISDMYDP+TKHVTKENDSKEGFFTYLCGFIKQKLALGGS+AVKITEH
Sbjct 6896 CATVHTANKWDLIISDMYDPKTKHVTKENDSKEGFFTYLCGFIKQKLALGGSVAVKITEH 6955
Query 6950 SWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNT 7009
SWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIG NYLGK +EQIDGYTMHANYIFWRNT
Sbjct 6956 SWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGVNYLGKLREQIDGYTMHANYIFWRNT 7015
Query 7010 NPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDI 7069
NPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLE GRLIIRENNRVVVSSDI
Sbjct 7016 NPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLENGRLIIRENNRVVVSSDI 7075
Query 7070 LVNN 7073
LVNN
Sbjct 7076 LVNN 7079
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 12939 bits (33580), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 6122/7103 (86%), Positives = 6597/7103 (93%), Gaps = 37/7103 (1%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDA + HGH +VELVAE++GIQYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGK+ CTLSEQLD+I++KRGVYCCR+HEHEIAW
Sbjct 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVASP ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
P NAVVK+ CPAC + E+GPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+Q+S+L+PL F S+A
Sbjct 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
A V+RSIF+RTL+ A +S+ LQ+AA+TILDGIS+ SLRL+DAM++TSDL TN++++MAY
Sbjct 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
+TGG+VQ TSQWL+N+ GT EKL+P+ +W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVC+NGLMLLEIKD E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV EVQGYK+V
Sbjct 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
WS+AT+YLFD++GE +S MYCSFYPPDE+EE+ EEE T ++EYGTEDDYQG
Sbjct 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPST-QYEYGTEDDYQGK 958
Query 961 PLEFGASAETVRVEEEEEEDWLDDTTEQS-------------------EIEP--EPEPTP 999
PLEFGA++ ++ EEE+EEDWLDD ++Q+ E++P E E TP
Sbjct 959 PLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
Query 1000 ---EEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKA 1056
VN F+GYLKLTDNV IK DIV+EA+ P V+VNAAN++LKHGGGVAGALNKA
Sbjct 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
Query 1057 TNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF 1116
TN AMQ ESDDYI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYENF
Sbjct 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
Query 1117 NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPR- 1175
N ++LLAPLLSAGIFGA P+ SL+VCV TVRT VY+AV DK LY+++V +L+ +
Sbjct 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
Query 1176 -----VEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLL 1230
E PK+E P +SK SV Q+ D K KIKAC++EVTTTLEETKFLT LL
Sbjct 1199 VEQKIAEIPKEEVKPFITESK---PSVEQRKQDDK-KIKACVEEVTTTLEETKFLTENLL 1254
Query 1231 LFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLS 1290
L+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML+
Sbjct 1255 LYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLA 1314
Query 1291 RALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWN 1350
+AL+KVP D YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSWN
Sbjct 1315 KALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWN 1374
Query 1351 LREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASI 1410
LREMLAHAEETRKLMP+C++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS+
Sbjct 1375 LREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASL 1434
Query 1411 ITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSS 1470
I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSSS
Sbjct 1435 INTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS 1494
Query 1471 KTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSL 1530
KT EEHF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGEV++
Sbjct 1495 KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVITF 1553
Query 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNH 1590
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH +H
Sbjct 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSH 1613
Query 1591 EGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN 1650
EGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNN
Sbjct 1614 EGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNN 1673
Query 1651 CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMT 1710
CYL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM+
Sbjct 1674 CYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMS 1733
Query 1711 HLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDA 1770
+L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+ A
Sbjct 1734 YLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQA 1793
Query 1771 TQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHL 1830
T+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA L
Sbjct 1794 TKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALL 1853
Query 1831 TKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPID 1890
TK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPID
Sbjct 1854 TKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPID 1913
Query 1891 LVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYR 1950
LVP QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY+
Sbjct 1914 LVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYK 1973
Query 1951 HYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDT 2010
HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1974 HYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDA 2033
Query 2011 QGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHE 2070
QGMDNLACE +P SEEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+GH
Sbjct 2034 QGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHT 2093
Query 2071 DLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITT 2130
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + TT
Sbjct 2094 DLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTT 2153
Query 2131 SNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
+N R RV NYMPY FTLL QLCTFT+STNSRI+AS+PTTIAKN+VKSV K CL+A
Sbjct 2154 TNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEA 2213
Query 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNS 2250
NY+KSP FSKL I +W LLLS+CLGSLI TAA GVL+SN G PSYC G RE YLNS
Sbjct 2214 SFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNS 2273
Query 2251 SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYML 2310
+NVT +C GS PCS+CLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+L
Sbjct 2274 TNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYIL 2333
Query 2311 FTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYI 2370
FT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY+
Sbjct 2334 FTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYV 2393
Query 2371 WKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCL 2430
WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC+
Sbjct 2394 WKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCV 2453
Query 2431 NCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTY 2490
NCDTFC GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV VKNG++HLYFDKAGQKTY
Sbjct 2454 NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTY 2513
Query 2491 ERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLD 2550
ERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES++KSASVYYSQLMCQPILLLD
Sbjct 2514 ERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLD 2573
Query 2551 QALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTF 2610
QALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF
Sbjct 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
Query 2611 VSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACID 2670
+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACID
Sbjct 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACID 2693
Query 2671 CNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNV 2730
C+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV
Sbjct 2694 CSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNV 2753
Query 2731 ITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
+TTKI+LKGGKIV+ K ++K TL+ + A + Y++ PVH +S H +++EIIGYKAI
Sbjct 2754 VTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAID 2813
Query 2791 DGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTV 2850
GVTRDI STD CFANKHA FD WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT+
Sbjct 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTI 2873
Query 2851 LRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYC 2910
LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYC
Sbjct 2874 LRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC 2933
Query 2911 YDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE 2970
YDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2934 YDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
Query 2971 VGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGII 3030
G+C+STSGRWVLNN++YR+L GVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+
Sbjct 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
Query 3031 AILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLT 3090
AI+VTC AYYFM+FRR FGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYSV YLYLT
Sbjct 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
Query 3091 FYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFS 3150
FY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNGV+FS
Sbjct 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFS 3173
Query 3151 TFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCH 3210
TFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCH
Sbjct 3174 TFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCH 3233
Query 3211 LAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3270
LAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL
Sbjct 3234 LAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
Query 3271 WLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLK 3330
WLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LK
Sbjct 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
Query 3331 VDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGF 3390
VDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGF
Sbjct 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
Query 3391 NIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA 3450
NIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYA
Sbjct 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
Query 3451 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKE
Sbjct 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
Query 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLI 3570
LLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+
Sbjct 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
Query 3571 LVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMV 3630
LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMV
Sbjct 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
Query 3631 YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMN 3690
YMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMN
Sbjct 3654 YMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMN 3713
Query 3691 VITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
V+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITG
Sbjct 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
Query 3751 NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKS 3810
NTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+
Sbjct 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
Query 3811 SIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3870
SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ
Sbjct 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
Query 3871 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPS 3930
LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPS
Sbjct 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPS 3953
Query 3931 YAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 3990
YAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY
Sbjct 3954 YAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 4013
Query 3991 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4050
KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV
Sbjct 4014 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4073
Query 4051 VPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA 4110
+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRA
Sbjct 4074 IPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 4133
Query 4111 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKW 4170
NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLKW
Sbjct 4134 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKW 4193
Query 4171 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4230
ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ
Sbjct 4194 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4253
Query 4231 AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4290
AGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE
Sbjct 4254 AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
Query 4291 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 4350
ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVC
Sbjct 4314 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVC 4373
Query 4351 GMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEK 4410
GMWKGYGCSCDQLREP++QSADA +FLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYN+K
Sbjct 4374 GMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDK 4433
Query 4411 VAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDF 4470
VAGFAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+KDCPAVA HDF
Sbjct 4434 VAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDF 4493
Query 4471 FKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD 4530
FKFR+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD
Sbjct 4494 FKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD 4553
Query 4531 WYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGD 4590
WYDFVENPDILRVYANLGERVRQ+LLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWYDFGD
Sbjct 4554 WYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGD 4613
Query 4591 FVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLC 4650
F+Q PG GVP+VDSYYSLLMPILTLTRAL AESH+D DL KP IKWDLLKYDFTEERL
Sbjct 4614 FIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLK 4673
Query 4651 LFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV 4710
LFDRYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV
Sbjct 4674 LFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV 4733
Query 4711 VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL 4770
VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL
Sbjct 4734 VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL 4793
Query 4771 TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP 4830
TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP
Sbjct 4794 TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP 4853
Query 4831 TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY 4890
TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY
Sbjct 4854 TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY 4913
Query 4891 EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA 4950
EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA
Sbjct 4914 EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA 4973
Query 4951 TRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARK 5010
TRGATVVIGTSKFYGGWHNMLKTVYSDVE PHLMGWDYPKCDRAMPNMLRIMASLVLARK
Sbjct 4974 TRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARK 5033
Query 5011 HNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT 5070
H TCC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT
Sbjct 5034 HTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT 5093
Query 5071 ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDD 5130
ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV+EFYAYLRKHFSMMILSDD
Sbjct 5094 ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDD 5153
Query 5131 AVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK 5190
AVVC+NS YA+QGLVASIKNFK+VLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK
Sbjct 5154 AVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK 5213
Query 5191 QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF 5250
QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF
Sbjct 5214 QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF 5273
Query 5251 HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN 5310
HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN
Sbjct 5274 HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN 5333
Query 5311 SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS 5370
SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS
Sbjct 5334 SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS 5393
Query 5371 YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER 5430
YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER
Sbjct 5394 YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER 5453
Query 5431 LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK 5490
LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK
Sbjct 5454 LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK 5513
Query 5491 NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI 5550
NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI
Sbjct 5514 NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI 5573
Query 5551 TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC 5610
TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC
Sbjct 5574 TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC 5633
Query 5611 SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD 5670
SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD
Sbjct 5634 SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD 5693
Query 5671 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM 5730
IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM
Sbjct 5694 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM 5753
Query 5731 KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN 5790
KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN
Sbjct 5754 KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN 5813
Query 5791 RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT 5850
RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT
Sbjct 5814 RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT 5873
Query 5851 TETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF 5910
TETAHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF
Sbjct 5874 TETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF 5933
Query 5911 KDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG 5970
KDCSK+ITGLHPTQAPTHLSVD KFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG
Sbjct 5934 KDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG 5993
Query 5971 YPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTE 6030
YPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAVPTGYVDT
Sbjct 5994 YPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTP 6053
Query 6031 NNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAH 6090
NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFVLWAH
Sbjct 6054 NNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAH 6113
Query 6091 GFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWG 6150
GFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPFMIDVQQWG
Sbjct 6114 GFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWG 6173
Query 6151 FTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSA 6210
FTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDEL++N+A
Sbjct 6174 FTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAA 6233
Query 6211 CRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFY 6270
CRKVQHMVVK+ALLADKFPVLHDIGNPKAIKCVPQA+VEWKFYDAQPCSDKAYKIEELFY
Sbjct 6234 CRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFY 6293
Query 6271 SYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT 6330
SYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT
Sbjct 6294 SYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT 6353
Query 6331 PAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA 6390
PAFDKSAF NLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA
Sbjct 6354 PAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA 6413
Query 6391 NEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGE 6450
NEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQSLENVA+NVVNKGHFDG GE
Sbjct 6414 NEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGE 6473
Query 6451 APVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAA 6510
PVSIINN VYTKVDG+DVE+FENKTTLPVNVAFELWAKRNIKPVPE+KILNNLGVDIAA
Sbjct 6474 VPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAA 6533
Query 6511 NTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGV 6570
NTVIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ LTV FDGRV+GQVDLFRNARNGV
Sbjct 6534 NTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGV 6593
Query 6571 LITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLE 6630
LITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQSR+L+
Sbjct 6594 LITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQ 6653
Query 6631 DFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDS 6690
+FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR ++S
Sbjct 6654 EFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKES 6713
Query 6691 PLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVT 6750
P +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV+SKVVKVT
Sbjct 6714 PFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVT 6773
Query 6751 IDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAV 6810
IDY EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG++A
Sbjct 6774 IDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSAT 6833
Query 6811 IPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL 6870
+PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL
Sbjct 6834 LPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL 6893
Query 6871 VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCG 6930
VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDP+TK+VTKENDSKEGFFTY+CG
Sbjct 6894 VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICG 6953
Query 6931 FIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKP 6990
FI+QKLALGGS+A+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NYLGKP
Sbjct 6954 FIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKP 7013
Query 6991 KEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLL 7050
+EQIDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI SLL
Sbjct 7014 REQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLL 7073
Query 7051 EKGRLIIRENNRVVVSSDILVNN 7073
KGRLIIRENNRVV+SSD+LVNN
Sbjct 7074 SKGRLIIRENNRVVISSDVLVNN 7096
>sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respiratory
syndrome coronavirus OX=694009 GN=1a PE=1 SV=1
Length=4382
Score = 9103 bits (23620), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 4378/4378 (100%), Positives = 4378/4378 (100%), Gaps = 0/4378 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW
Sbjct 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL
Sbjct 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY
Sbjct 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV
Sbjct 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC
Sbjct 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV
Sbjct 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL
Sbjct 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
Query 961 PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC 1020
PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC
Sbjct 961 PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC 1020
Query 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS
Sbjct 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
Query 1081 CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL 1140
CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL
Sbjct 1081 CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL 1140
Query 1141 QVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK 1200
QVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK
Sbjct 1141 QVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK 1200
Query 1201 PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP 1260
PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP
Sbjct 1201 PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP 1260
Query 1261 YMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKT 1320
YMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKT
Sbjct 1261 YMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKT 1320
Query 1321 ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQR 1380
ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQR
Sbjct 1321 ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQR 1380
Query 1381 KYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAAR 1440
KYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAAR
Sbjct 1381 KYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAAR 1440
Query 1441 CMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG 1500
CMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG
Sbjct 1441 CMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG 1500
Query 1501 VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQL 1560
VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQL
Sbjct 1501 VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQL 1560
Query 1561 VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFL 1620
VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFL
Sbjct 1561 VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFL 1620
Query 1621 GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR 1680
GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR
Sbjct 1621 GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR 1680
Query 1681 AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT 1740
AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT
Sbjct 1681 AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT 1740
Query 1741 GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC 1800
GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC
Sbjct 1741 GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC 1800
Query 1801 ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYK 1860
ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYK
Sbjct 1801 ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYK 1860
Query 1861 LDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQ 1920
LDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQ
Sbjct 1861 LDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQ 1920
Query 1921 MTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF 1980
MTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF
Sbjct 1921 MTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF 1980
Query 1981 KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE 2040
KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE
Sbjct 1981 KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE 2040
Query 2041 CDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA 2100
CDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA
Sbjct 2041 CDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA 2100
Query 2101 THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFT 2160
THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFT
Sbjct 2101 THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFT 2160
Query 2161 KSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSL 2220
KSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSL
Sbjct 2161 KSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSL 2220
Query 2221 ICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPA 2280
ICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPA
Sbjct 2221 ICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPA 2280
Query 2281 LETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW 2340
LETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW
Sbjct 2281 LETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW 2340
Query 2341 LMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC 2400
LMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC
Sbjct 2341 LMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC 2400
Query 2401 TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINP 2460
TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINP
Sbjct 2401 TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINP 2460
Query 2461 TDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVF 2520
TDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVF
Sbjct 2461 TDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVF 2520
Query 2521 DGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFS 2580
DGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFS
Sbjct 2521 DGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFS 2580
Query 2581 VPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDL 2640
VPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDL
Sbjct 2581 VPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDL 2640
Query 2641 EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE 2700
EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE
Sbjct 2641 EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE 2700
Query 2701 QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLA 2760
QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLA
Sbjct 2701 QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLA 2760
Query 2761 ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG 2820
ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG
Sbjct 2761 ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG 2820
Query 2821 SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLI 2880
SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLI
Sbjct 2821 SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLI 2880
Query 2881 EYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQ 2940
EYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQ
Sbjct 2881 EYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQ 2940
Query 2941 FPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA 3000
FPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA
Sbjct 2941 FPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA 3000
Query 3001 MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANAL 3060
MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANAL
Sbjct 3001 MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANAL 3060
Query 3061 LFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAI 3120
LFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAI
Sbjct 3061 LFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAI 3120
Query 3121 YVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ 3180
YVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ
Sbjct 3121 YVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ 3180
Query 3181 YNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQ 3240
YNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQ
Sbjct 3181 YNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQ 3240
Query 3241 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3300
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR
Sbjct 3241 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3300
Query 3301 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3301 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
Query 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK
Sbjct 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
Query 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
Query 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC
Sbjct 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
Query 3541 SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA 3600
SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA
Sbjct 3541 SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA 3600
Query 3601 CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCV 3660
CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCV
Sbjct 3601 CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCV 3660
Query 3661 MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN 3720
MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN
Sbjct 3661 MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN 3720
Query 3721 YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY
Sbjct 3721 YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
Query 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS
Sbjct 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
Query 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG
Sbjct 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
Query 3901 AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKS 3960
AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKS
Sbjct 3901 AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKS 3960
Query 3961 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4020
LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND
Sbjct 3961 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4020
Query 4021 ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD 4080
ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD
Sbjct 4021 ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD 4080
Query 4081 ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTAC 4140
ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTAC
Sbjct 4081 ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTAC 4140
Query 4141 TDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP 4200
TDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP
Sbjct 4141 TDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP 4200
Query 4201 KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDY 4260
KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDY
Sbjct 4201 KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDY 4260
Query 4261 LASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFC 4320
LASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFC
Sbjct 4261 LASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFC 4320
Query 4321 DLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
DLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN
Sbjct 4321 DLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
>sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus
Rp3/2004 OX=349344 GN=1a PE=3 SV=1
Length=4380
Score = 8822 bits (22892), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 4228/4379 (97%), Positives = 4298/4379 (98%), Gaps = 4/4379 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLVLG+NEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLK+GTCG+VELEKGV
Sbjct 1 MESLVLGINEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKSGTCGIVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQ EQPYVFIKRSDA T+HGH+V ELVAE+DG+QYGRSGITLGVLVPHVGETPIAYRN
Sbjct 61 LPQPEQPYVFIKRSDAQGTDHGHRVRELVAELDGVQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHS+GIDLKSYDLGDELGTDPIEDYEQNWNTKHGSG LRELTRELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGVLRELTRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
A+TRYVDNNFCGPDGYPL+CIKD LARAGKSMCTLSEQLDYIESKRGVYCCRDH HEIAW
Sbjct 181 ALTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCRDHGHEIAW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVA+PQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCE CGTENLV EGP TCGYL
Sbjct 301 RSVYPVATPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVSEGPNTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
PTNAVVKMPCPACQDPEIGPEHS ADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSAADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDF LNEEVAIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFQLNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKP+KGAWNIGQ RSVLTPLCGFPSQA
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPIKGAWNIGQHRSVLTPLCGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIF+RTLDAANHSIPDLQRAAVTILD ISEQSLRLVDAMVYTS+LLTNSVIIMAY
Sbjct 541 AGVIRSIFSRTLDAANHSIPDLQRAAVTILDSISEQSLRLVDAMVYTSNLLTNSVIIMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQTSQWLSNLL TTVEKLRPIF WIEAKLSAGVEFLKDAWEILKFLITGVFDIV
Sbjct 601 VTGGLVQQTSQWLSNLLDTTVEKLRPIFAWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVASDNIKDCVKCF+DVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC
Sbjct 661 KGQIQVASDNIKDCVKCFVDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGA+VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAVVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVC+NGLMLLEIK EQYCALSPGLLATNNVFRLKGGAP KGVTFGEDTV EVQGYKNV
Sbjct 781 TPVCINGLMLLEIKANEQYCALSPGLLATNNVFRLKGGAPTKGVTFGEDTVVEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDE-TCEHEYGTEDDYQG 959
WSVATFYLFDD+GEE SSRMYCSFYPPDEEE+ + EEEE+ E TCEHEYGTE+DY+G
Sbjct 901 WSVATFYLFDDSGEEKLSSRMYCSFYPPDEEEDCEEYEEEEEVSERTCEHEYGTEEDYKG 960
Query 960 LPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
LPLEFGAS + ++VEE+EEEDWLDD E EPEPEP EEPVNQ TGYLKLTDNVAIK
Sbjct 961 LPLEFGASTDIIQVEEQEEEDWLDDAVEA---EPEPEPLHEEPVNQLTGYLKLTDNVAIK 1017
Query 1020 CVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGG 1079
CVDIV+EAQ+ANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESD YIKLNGPLTVGG
Sbjct 1018 CVDIVEEAQNANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDHYIKLNGPLTVGG 1077
Query 1080 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1139
SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS
Sbjct 1078 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1137
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQ 1199
LQ+CVQTVRTQVYI VNDK LYEQVVMDYLD+LKP+VEAPKQE P E K +EKSVVQ
Sbjct 1138 LQMCVQTVRTQVYIVVNDKVLYEQVVMDYLDSLKPKVEAPKQEVLPKAEYPKVDEKSVVQ 1197
Query 1200 KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDA 1259
K +DVKPKIKACIDEVTTTLEETKFLTNKLLLF DINGKLY DS+NMLRGEDMSFLEKDA
Sbjct 1198 KTIDVKPKIKACIDEVTTTLEETKFLTNKLLLFTDINGKLYQDSKNMLRGEDMSFLEKDA 1257
Query 1260 PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAK 1319
PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVP++EYITTYPGQGCAGYTLEEAK
Sbjct 1258 PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPINEYITTYPGQGCAGYTLEEAK 1317
Query 1320 TALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQ 1379
TALKKCKSAFYVLPSE PNAKEEILGTVSWNLREMLAHAEETRKLMP+CMDVRAIMATIQ
Sbjct 1318 TALKKCKSAFYVLPSETPNAKEEILGTVSWNLREMLAHAEETRKLMPVCMDVRAIMATIQ 1377
Query 1380 RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA 1439
RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA
Sbjct 1378 RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA 1437
Query 1440 RCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTEL 1499
RCMRSLKAPA+VSVSSPDAVTTYNGYLTSSSKTSE+HFVETVSLAGSYRDWSYSGQRTEL
Sbjct 1438 RCMRSLKAPAIVSVSSPDAVTTYNGYLTSSSKTSEDHFVETVSLAGSYRDWSYSGQRTEL 1497
Query 1500 GVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQ 1559
GVEFLKRG+KIVYHTLESPV+FHLDGEVL LDKLKSLLSLREVKTIKVFTTVDNTNLHTQ
Sbjct 1498 GVEFLKRGEKIVYHTLESPVKFHLDGEVLPLDKLKSLLSLREVKTIKVFTTVDNTNLHTQ 1557
Query 1560 LVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF 1619
LVDMSMTYGQQ GPTYL+GADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF
Sbjct 1558 LVDMSMTYGQQLGPTYLEGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF 1617
Query 1620 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRA 1679
LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ+EVKFNAPALQEAYYRA
Sbjct 1618 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQIEVKFNAPALQEAYYRA 1677
Query 1680 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1739
RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL
Sbjct 1678 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1737
Query 1740 TGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL 1799
TGVEAVMYMGTLSYDNLK GVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL
Sbjct 1738 TGVEAVMYMGTLSYDNLKMGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL 1797
Query 1800 CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY 1859
CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY
Sbjct 1798 CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY 1857
Query 1860 KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLN 1919
KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL+PTQPLPNASFDNFKLTCSNTKFADDLN
Sbjct 1858 KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLIPTQPLPNASFDNFKLTCSNTKFADDLN 1917
Query 1920 QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT 1979
QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT
Sbjct 1918 QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT 1977
Query 1980 FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVI 2039
FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPT EEVVENPTIQKEVI
Sbjct 1978 FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTPEEVVENPTIQKEVI 2037
Query 2040 ECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTI 2099
ECDVKTTEVVGNVILKPSDEGVKVTQEL HEDLMAAYVENTSITIKKPNELSLALGLKTI
Sbjct 2038 ECDVKTTEVVGNVILKPSDEGVKVTQELDHEDLMAAYVENTSITIKKPNELSLALGLKTI 2097
Query 2100 ATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTF 2159
ATHGIAAINSVPW KILAYVKPFLGQAA+TTSNCAKRL QR+FNNYMPYV TLLFQLCTF
Sbjct 2098 ATHGIAAINSVPWGKILAYVKPFLGQAAVTTSNCAKRLVQRMFNNYMPYVLTLLFQLCTF 2157
Query 2160 TKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS 2219
TKSTNSRIRASLPTTIAKNSV+ + +LCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS
Sbjct 2158 TKSTNSRIRASLPTTIAKNSVRGIVRLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS 2217
Query 2220 LICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYP 2279
LI VTAA GVLLSNFGAPSYC+GVRE YLNSSNVTTMDFCEGSFPCS+CLSGLDSLDSYP
Sbjct 2218 LIYVTAALGVLLSNFGAPSYCSGVRESYLNSSNVTTMDFCEGSFPCSVCLSGLDSLDSYP 2277
Query 2280 ALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2339
ALETIQVTISSYKLDLTILGLAAEW AYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS
Sbjct 2278 ALETIQVTISSYKLDLTILGLAAEWFFAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2337
Query 2340 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2399
WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE
Sbjct 2338 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2397
Query 2400 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPIN 2459
CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFC GSTFISDEVARDLSLQFKRPIN
Sbjct 2398 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCAGSTFISDEVARDLSLQFKRPIN 2457
Query 2460 PTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2519
PTDQSSY+VDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV
Sbjct 2458 PTDQSSYVVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2517
Query 2520 FDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2579
FDGKSKCDESA+KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF
Sbjct 2518 FDGKSKCDESAAKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2577
Query 2580 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD 2639
SVPMEKLKALVATAHSELAKGVALDGVLSTFVSA+RQGVVDTDVDTKDVIECLKLSHHSD
Sbjct 2578 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSASRQGVVDTDVDTKDVIECLKLSHHSD 2637
Query 2640 LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLS 2699
LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVA+SHNVSLIWNVKDYMSLS
Sbjct 2638 LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVARSHNVSLIWNVKDYMSLS 2697
Query 2700 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVL 2759
EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVST FK+MLKATLLCVL
Sbjct 2698 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTWFKIMLKATLLCVL 2757
Query 2760 AALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRG 2819
AALVCYIVMPVH LS+H GYTNEIIGYKAIQDGVTRDI+STDDCFANKHAGFD+WFSQRG
Sbjct 2758 AALVCYIVMPVHILSVHGGYTNEIIGYKAIQDGVTRDIVSTDDCFANKHAGFDSWFSQRG 2817
Query 2820 GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL
Sbjct 2818 GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2877
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2939
IEYSDF+TSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII
Sbjct 2878 IEYSDFSTSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2937
Query 2940 QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVD 2999
QFPN YLEGSVRVVTTFDAEYCRHGTCERSE GICLSTSGRWVLNNEHYRAL GVFCGVD
Sbjct 2938 QFPNAYLEGSVRVVTTFDAEYCRHGTCERSEAGICLSTSGRWVLNNEHYRALPGVFCGVD 2997
Query 3000 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANA 3059
AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRR FGEYNHVVAANA
Sbjct 2998 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRAFGEYNHVVAANA 3057
Query 3060 LLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3119
LFLMSFTILCL PAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA
Sbjct 3058 PLFLMSFTILCLAPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3117
Query 3120 IYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3179
IYVFCISLKH HWFFNNYLRKRV+FNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT
Sbjct 3118 IYVFCISLKHFHWFFNNYLRKRVVFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3177
Query 3180 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3239
QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL
Sbjct 3178 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3237
Query 3240 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI 3299
QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI
Sbjct 3238 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI 3297
Query 3300 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3359
RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN
Sbjct 3298 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3357
Query 3360 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3419
GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT VHAGTDLEG
Sbjct 3358 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTEVHAGTDLEG 3417
Query 3420 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3479
KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY
Sbjct 3418 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3477
Query 3480 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3539
EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ
Sbjct 3478 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3537
Query 3540 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIA 3599
CSGVTFQGKFK+IVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA+A
Sbjct 3538 CSGVTFQGKFKRIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAVA 3597
Query 3600 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3659
ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC
Sbjct 3598 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3657
Query 3660 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3719
VMYASALVLL+LMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS
Sbjct 3658 VMYASALVLLVLMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3717
Query 3720 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3779
NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR
Sbjct 3718 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3777
Query 3780 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3839
YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM
Sbjct 3778 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3837
Query 3840 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3899
SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ
Sbjct 3838 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3897
Query 3900 GAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3959
GAVDIN+LCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK
Sbjct 3898 GAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3957
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
SLNVAKSEFDR+AAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN
Sbjct 3958 SLNVAKSEFDRNAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4017
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV
Sbjct 4018 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4077
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4139
DADSKIVQLSEINM+NS NLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA
Sbjct 4078 DADSKIVQLSEINMENSSNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4137
Query 4140 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4199
CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG
Sbjct 4138 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4197
Query 4200 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4259
PKVKYL+FIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD
Sbjct 4198 PKVKYLHFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4257
Query 4260 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4319
YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF
Sbjct 4258 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4317
Query 4320 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP+MQSADASTFLN
Sbjct 4318 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPMMQSADASTFLN 4376
>sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus
HKU3 OX=442736 GN=1a PE=3 SV=1
Length=4376
Score = 8547 bits (22178), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 4113/4379 (94%), Positives = 4251/4379 (97%), Gaps = 8/4379 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDALSTNHGHKVVELVAE+DGIQ+GRSGITLGVLVPHVGETPIAYRN
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAELDGIQFGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHS+GIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
VTRYVDNNFCGPDGYPL+CIKDFLARAGKSMCTLSEQLDYIESKRGVYCCR+HEHEI W
Sbjct 181 VVTRYVDNNFCGPDGYPLECIKDFLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERS+KSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSEKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVA+PQECN+MHLSTLMKCNHCDEVSWQTCDFLKATCE CGTENLV EGPTTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
PTNAVVKMPCPACQDPE+GPEHSVADYHNHSNIETRLRKGGRT+CFGGCVF+YVGCYNKR
Sbjct 361 PTNAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFSYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASA+IG+ HTGITG+NVETLNEDLLEIL+RERVNINIVGDF NEEVAIILASF
Sbjct 421 AYWVPRASANIGANHTGITGENVETLNEDLLEILNRERVNINIVGDFRFNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SAS SAFI+T+K LDYKSFK IVESCGNYKVT GKPV GAWNIGQQRS+LTPLCGFPSQA
Sbjct 481 SASPSAFIETVKGLDYKSFKVIVESCGNYKVTNGKPVTGAWNIGQQRSILTPLCGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIF+RTLDAANHSI DLQRAAVT LDGISEQSLRLVDAMVYTSDLLTNSV++MAY
Sbjct 541 AGVIRSIFSRTLDAANHSILDLQRAAVTTLDGISEQSLRLVDAMVYTSDLLTNSVVVMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQT QWLSN+LGT V+KL+P+F W+EAKLSAGVEFL+DAWEILKFLITGVFD++
Sbjct 601 VTGGLVQQTMQWLSNMLGTAVDKLKPVFTWVEAKLSAGVEFLRDAWEILKFLITGVFDVI 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVA+DNIK+CVK F+ VVNKALEMC+DQVTIAG KLR+LNLGEVFIAQS+GLYRQC
Sbjct 661 KGQIQVATDNIKECVKIFLGVVNKALEMCLDQVTIAGTKLRALNLGEVFIAQSRGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPLKAPKEVTFLEGD+HDTVLTSEEVVLK+GELEALETP+DSFT+GA+VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDAHDTVLTSEEVVLKSGELEALETPIDSFTSGAVVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVC+NGLMLLE+++KEQYCALSPGLLATNNVFRLKGGAP+KGVTFGEDTV EVQGYKNV
Sbjct 781 TPVCINGLMLLELENKEQYCALSPGLLATNNVFRLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
+ITFELD RVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLT MGIDLDE
Sbjct 841 KITFELDVRVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTPMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
WSVATFYLFDDAGEE SSRMYCSFYPPDEEE+ + +EEE E EYGTEDDY+GL
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEECEDEEETCEH---EYGTEDDYKGL 957
Query 961 PLEFGASAETVRVEEEEEE-DWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
PLEFGAS ET VEEEEEE DWLDD E PEEPVNQF GYLKLTDNVAIK
Sbjct 958 PLEFGASTETPHVEEEEEEEDWLDDAIEAEPEPEP---LPEEPVNQFVGYLKLTDNVAIK 1014
Query 1020 CVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGG 1079
C+DIVKEAQSA P VIVNAAN HLKHGGGVAGALNKATNGAMQ ESD+YI+ NGPLTVGG
Sbjct 1015 CIDIVKEAQSAKPTVIVNAANTHLKHGGGVAGALNKATNGAMQNESDEYIRQNGPLTVGG 1074
Query 1080 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1139
SCLLSGHNLA+KCLHVVGPNLNAGED+QLLK AYENFNSQD+LLAPLLSAGIFGAKPLQS
Sbjct 1075 SCLLSGHNLAEKCLHVVGPNLNAGEDVQLLKRAYENFNSQDVLLAPLLSAGIFGAKPLQS 1134
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQ 1199
L++CV+ VRTQVY+AVNDK+LY+Q+V+DYLD+LKP+VE+P +EE P E+ K + V +
Sbjct 1135 LKMCVEIVRTQVYLAVNDKSLYDQIVLDYLDSLKPKVESPNKEEEPKLEEPKAVQ-PVAE 1193
Query 1200 KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDA 1259
KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLY DSQNMLRGEDMSFLEKDA
Sbjct 1194 KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYQDSQNMLRGEDMSFLEKDA 1253
Query 1260 PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAK 1319
PY+VGDVITSGDITCV+IP+KK+GGTTEML+RALK+VPV EYITTYPGQGCAGYTLEEAK
Sbjct 1254 PYIVGDVITSGDITCVIIPAKKSGGTTEMLARALKEVPVAEYITTYPGQGCAGYTLEEAK 1313
Query 1320 TALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQ 1379
TALKKCKSAFYVLPSE PN KEE+LGTVSWNLREMLAHAEETRKLMPIC+DVRAIMATIQ
Sbjct 1314 TALKKCKSAFYVLPSETPNEKEEVLGTVSWNLREMLAHAEETRKLMPICLDVRAIMATIQ 1373
Query 1380 RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA 1439
RKYKGIK+QEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHG NLEEAA
Sbjct 1374 RKYKGIKVQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGLNLEEAA 1433
Query 1440 RCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTEL 1499
RCMRSLKAPAVVSVSSPDAVT YNGYLTSSSKT EE+FVET SLAGSYRDWSYSGQRTEL
Sbjct 1434 RCMRSLKAPAVVSVSSPDAVTAYNGYLTSSSKTPEEYFVETTSLAGSYRDWSYSGQRTEL 1493
Query 1500 GVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQ 1559
GVEFLKRGDKIVYHT SP+EFHLDGEVL LDKLKSLLSLREVKTIKVFTTVDNTNLHT
Sbjct 1494 GVEFLKRGDKIVYHTTGSPIEFHLDGEVLPLDKLKSLLSLREVKTIKVFTTVDNTNLHTH 1553
Query 1560 LVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF 1619
+VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHT+DESF
Sbjct 1554 IVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTIDESF 1613
Query 1620 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRA 1679
LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ+EVKFNAPALQEAYYRA
Sbjct 1614 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQVEVKFNAPALQEAYYRA 1673
Query 1680 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1739
RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL
Sbjct 1674 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1733
Query 1740 TGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL 1799
GVEAVMYMGTLSYD LKTGVSIPCVCGR+ATQYLVQQESSFVMMSAPPAEYKLQQG FL
Sbjct 1734 KGVEAVMYMGTLSYDELKTGVSIPCVCGRNATQYLVQQESSFVMMSAPPAEYKLQQGAFL 1793
Query 1800 CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY 1859
CANEYTGNYQCGHYTHITAKETLYR+DGAHLTKMSEYKGPVTDVFYKETSYTT IKPVSY
Sbjct 1794 CANEYTGNYQCGHYTHITAKETLYRVDGAHLTKMSEYKGPVTDVFYKETSYTTAIKPVSY 1853
Query 1860 KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLN 1919
KLDGVTYTEIEPKLDGYYKK NAYYTEQPIDLVPTQP+PNASFDNFKLTCSNTKFADDLN
Sbjct 1854 KLDGVTYTEIEPKLDGYYKKGNAYYTEQPIDLVPTQPMPNASFDNFKLTCSNTKFADDLN 1913
Query 1920 QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT 1979
QMTGF KPASREL+VTFFPDLNGDVVAIDYRHYS SFKKGAKL+HKPI+WHINQ T KTT
Sbjct 1914 QMTGFKKPASRELTVTFFPDLNGDVVAIDYRHYSTSFKKGAKLVHKPILWHINQTTNKTT 1973
Query 1980 FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVI 2039
+KPN WCLRCLWSTKPVDTSNSFEVL VEDTQGMDNLACESQ TSEEVVENPT+QKE+I
Sbjct 1974 YKPNIWCLRCLWSTKPVDTSNSFEVLVVEDTQGMDNLACESQTTTSEEVVENPTVQKEII 2033
Query 2040 ECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTI 2099
ECDVKTTEVVGNVILKPS+EGVKVTQELGHEDLMAAYVE TSITIKKPNELSLALGLKT+
Sbjct 2034 ECDVKTTEVVGNVILKPSEEGVKVTQELGHEDLMAAYVEETSITIKKPNELSLALGLKTL 2093
Query 2100 ATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTF 2159
ATHG AAINSVPWSKILAYVKPFLGQ A+ TSNC K+ QRVF+NYMPYV TLLFQLCTF
Sbjct 2094 ATHGAAAINSVPWSKILAYVKPFLGQTAVITSNCIKKCVQRVFSNYMPYVITLLFQLCTF 2153
Query 2160 TKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS 2219
TKSTNSRI+ASLPTTIAKNSVKSVAKLCLD INYVKSPKFSKLFTI MWLLLLSICLGS
Sbjct 2154 TKSTNSRIKASLPTTIAKNSVKSVAKLCLDVCINYVKSPKFSKLFTIVMWLLLLSICLGS 2213
Query 2220 LICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYP 2279
L VTA GV LS+ G PSYC+GVRELY+NSSNVTTMDFC+G FPCS+CLSGLDSLDSYP
Sbjct 2214 LTYVTAVLGVCLSSLGVPSYCDGVRELYINSSNVTTMDFCQGYFPCSVCLSGLDSLDSYP 2273
Query 2280 ALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2339
ALETIQVTISSYKLDLT LGLAAEW+LAYMLFTKFFYLLGLSAIMQ FFGYFASHFISNS
Sbjct 2274 ALETIQVTISSYKLDLTFLGLAAEWLLAYMLFTKFFYLLGLSAIMQAFFGYFASHFISNS 2333
Query 2340 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2399
WLMWFIISIVQMAPVSAMVRMYIFFASFYY+WKSYVHIMDGCTSSTCMMCYKRNRATRVE
Sbjct 2334 WLMWFIISIVQMAPVSAMVRMYIFFASFYYVWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2393
Query 2400 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPIN 2459
CTTIVNG+KRSFYVYANGGRGFCK HNWNCLNCDTFC GSTFISDEVARDLSLQFKRPIN
Sbjct 2394 CTTIVNGVKRSFYVYANGGRGFCKAHNWNCLNCDTFCAGSTFISDEVARDLSLQFKRPIN 2453
Query 2460 PTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2519
PTDQS+Y+VDSV VKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV
Sbjct 2454 PTDQSAYVVDSVTVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2513
Query 2520 FDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2579
FDGKSKC+ESA+KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF
Sbjct 2514 FDGKSKCEESAAKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2573
Query 2580 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD 2639
SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD
Sbjct 2574 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD 2633
Query 2640 LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLS 2699
+EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSL+WNVKDYMSLS
Sbjct 2634 IEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLVWNVKDYMSLS 2693
Query 2700 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVL 2759
EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGK+VST FKL+LK TLLCVL
Sbjct 2694 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKVVSTWFKLLLKVTLLCVL 2753
Query 2760 AALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRG 2819
AAL CY++MPVH+LS+HDGYTNEIIGYKAIQDGVTRDI+STDDCFANKHAGFD+WFSQRG
Sbjct 2754 AALFCYVIMPVHSLSVHDGYTNEIIGYKAIQDGVTRDIVSTDDCFANKHAGFDSWFSQRG 2813
Query 2820 GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
GSY+NDK+CPVVAAIITREIGFIVPGLPGTVLRA+NGDFLHFLPRVFSAVGNICYTPSKL
Sbjct 2814 GSYRNDKNCPVVAAIITREIGFIVPGLPGTVLRALNGDFLHFLPRVFSAVGNICYTPSKL 2873
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2939
IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII
Sbjct 2874 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2933
Query 2940 QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVD 2999
QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVG+CLSTSGRWVLNNEHYRAL GVFCGVD
Sbjct 2934 QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGVCLSTSGRWVLNNEHYRALPGVFCGVD 2993
Query 3000 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANA 3059
AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRR FGEYNHVVAANA
Sbjct 2994 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRAFGEYNHVVAANA 3053
Query 3060 LLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3119
LLFLMSFTILCL PAYSFLPGVYS+FYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA
Sbjct 3054 LLFLMSFTILCLAPAYSFLPGVYSIFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3113
Query 3120 IYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3179
IYVFCISLKH HWFF+NYL+KRVMFNGVTFSTFEEAALCTFLLNKEMYL+LRSETLLPLT
Sbjct 3114 IYVFCISLKHFHWFFSNYLKKRVMFNGVTFSTFEEAALCTFLLNKEMYLRLRSETLLPLT 3173
Query 3180 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3239
QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL
Sbjct 3174 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3233
Query 3240 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI 3299
QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHV+CTAEDMLNPNY+DLLI
Sbjct 3234 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVVCTAEDMLNPNYDDLLI 3293
Query 3300 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3359
RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN
Sbjct 3294 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3353
Query 3360 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3419
GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3354 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3413
Query 3420 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3479
KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY
Sbjct 3414 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3473
Query 3480 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3539
EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ
Sbjct 3474 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3533
Query 3540 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIA 3599
CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPF LGIMA+A
Sbjct 3534 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFALGIMAVA 3593
Query 3600 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3659
ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC
Sbjct 3594 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3653
Query 3660 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3719
VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGN+LDQAISMWALVISVTS
Sbjct 3654 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAISMWALVISVTS 3713
Query 3720 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3779
NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR
Sbjct 3714 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3773
Query 3780 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3839
YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM
Sbjct 3774 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3833
Query 3840 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3899
SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ
Sbjct 3834 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3893
Query 3900 GAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3959
GAVDIN+LCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAV+NGDSEVVLKKLKK
Sbjct 3894 GAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVSNGDSEVVLKKLKK 3953
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
SLNVAKSEFD DAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN
Sbjct 3954 SLNVAKSEFDHDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4013
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV
Sbjct 4014 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4073
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4139
DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA
Sbjct 4074 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4133
Query 4140 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4199
CTDDNALAYYNN+KGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG
Sbjct 4134 CTDDNALAYYNNAKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4193
Query 4200 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4259
PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD
Sbjct 4194 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4253
Query 4260 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4319
YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF
Sbjct 4254 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4313
Query 4320 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP+MQSADASTFLN
Sbjct 4314 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPMMQSADASTFLN 4372
>sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus
279/2005 OX=389167 GN=1a PE=3 SV=1
Length=4388
Score = 8495 bits (22042), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 4093/4389 (93%), Positives = 4237/4389 (97%), Gaps = 16/4389 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESL LGV+EKTHVQLSLPVLQVRDVLVRGFGDSVEEAL+EAREHLKNGTCGLVELEKGV
Sbjct 1 MESLALGVSEKTHVQLSLPVLQVRDVLVRGFGDSVEEALAEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDA TNHG+KVVELVAE+DGIQYGRSG TLGVLVPHVGETP+AYRN
Sbjct 61 LPQLEQPYVFIKRSDAQGTNHGYKVVELVAELDGIQYGRSGTTLGVLVPHVGETPVAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHSYGIDLKSYDLG ELGTDPIEDYEQNWNTKHG G LREL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGVELGTDPIEDYEQNWNTKHGGGVLRELIRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGKSMCTLSEQLDYIESKRGVYCCR+HEHEI W
Sbjct 181 AFTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERS+KSYE QTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSEKSYERQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVA+PQECN+MHLSTLMKCNHCDEVSWQTCDFLKATCE CGTENLV EGPTTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
P NAVVKMPCPACQDPE+GPEHSVADYHNHSNIETRLRKGGRT+CFGGCVFAYVGCYNKR
Sbjct 361 PANAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASA+IG+ HTGITGDNVETLNEDL+EIL+R+RVNINIVGDFHLNEEVAIILASF
Sbjct 421 AYWVPRASANIGASHTGITGDNVETLNEDLMEILNRDRVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SAST AF+DT+K LDYK+FK IVESCGN+KVT+G+ KGAWNIGQ++S+LTPL GFPSQA
Sbjct 481 SASTCAFVDTVKGLDYKTFKDIVESCGNFKVTRGRAKKGAWNIGQEKSILTPLYGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIF R LD ANHSIPDLQRAA+TILDGISEQSLRL+DAMVYTSDLLTNSVI+MAY
Sbjct 541 AGVIRSIFTRALDTANHSIPDLQRAAITILDGISEQSLRLIDAMVYTSDLLTNSVIVMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQ +QWLSN+LGTTV+KL+P+F W+EAKLSAG+EFL+DAWEILKFL+TGVFDIV
Sbjct 601 VTGGLVQQITQWLSNMLGTTVDKLKPVFTWVEAKLSAGIEFLRDAWEILKFLVTGVFDIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVASDN+K+CVK F+DV+NKALEMCIDQV IAGAKLR+LNLGEVFIAQSKGLYRQC
Sbjct 661 KGQIQVASDNLKECVKAFLDVLNKALEMCIDQVIIAGAKLRTLNLGEVFIAQSKGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPL+APKEVTF EGDSHDTV TSEEVVLKNGELEALETPVDSFTNGA++G
Sbjct 721 IRGKEQLQLLMPLRAPKEVTFFEGDSHDTVFTSEEVVLKNGELEALETPVDSFTNGAVIG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVCVNGLMLLE+KDKEQYCALSPGLLATNNVF LKGGAP+KGVTFGEDTV EVQGYKNV
Sbjct 781 TPVCVNGLMLLELKDKEQYCALSPGLLATNNVFSLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
+ITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
Sbjct 841 KITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCE-HEYGTEDDYQG 959
WSVATFYLFDDAGEE SSRMYCSFYPPDEEE+ + +EEEI E HEYGTEDDY+G
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEEYEDEEEIPEETCEHEYGTEDDYKG 960
Query 960 LPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
LPLEFGAS E +++ +EE+ D E +PEPEP PEEPVNQFTGYLKLTDNVAIK
Sbjct 961 LPLEFGASTE---IQQVDEEEEEDWLEEAIAAKPEPEPLPEEPVNQFTGYLKLTDNVAIK 1017
Query 1020 CVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGG 1079
CVDIVKEAQ A P VIVNAAN+HLKHGGGVAGALNKATNGAMQ+ESDDYIK NGPLTVGG
Sbjct 1018 CVDIVKEAQHAKPTVIVNAANVHLKHGGGVAGALNKATNGAMQQESDDYIKKNGPLTVGG 1077
Query 1080 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1139
SCLLSGHNLAKKC+HVVGPNLNAGED+QLLKAAY NFNSQD+LLAPLLSAGIFGAKPLQS
Sbjct 1078 SCLLSGHNLAKKCMHVVGPNLNAGEDVQLLKAAYANFNSQDVLLAPLLSAGIFGAKPLQS 1137
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQE----------EPPNTED 1189
L++CV+TVRTQVY AVND+ LY+ VV+ YLD+LKP+VE P QE E E+
Sbjct 1138 LKMCVETVRTQVYFAVNDQDLYDHVVLGYLDSLKPKVETPTQENLELKEQPAVETLTQEN 1197
Query 1190 SKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRG 1249
+ EE V++KPVDVK KA I+EV T+LEETKFLT++LLLFADINGKLY DSQNMLRG
Sbjct 1198 LELEELPVIEKPVDVK--FKARIEEVNTSLEETKFLTSRLLLFADINGKLYQDSQNMLRG 1255
Query 1250 EDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQG 1309
EDM FLEKDAPY+VGDVI+SGDITCV+IP+KKAGGTTEML++ALKKVPV EYITTYPGQG
Sbjct 1256 EDMFFLEKDAPYIVGDVISSGDITCVIIPAKKAGGTTEMLAKALKKVPVSEYITTYPGQG 1315
Query 1310 CAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICM 1369
CAGYTLEEAKTAL+KCKS FYVLPS+ PN KEEILGTVSWNLREMLAHAEETRKLM ICM
Sbjct 1316 CAGYTLEEAKTALRKCKSVFYVLPSKTPNDKEEILGTVSWNLREMLAHAEETRKLMLICM 1375
Query 1370 DVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYV 1429
DV+A+M+TI R+YKGIK+QEGIVDYGVRFFFYTSKEPVASIITKLN LNEPLVTMPIGYV
Sbjct 1376 DVKALMSTIHRRYKGIKVQEGIVDYGVRFFFYTSKEPVASIITKLNLLNEPLVTMPIGYV 1435
Query 1430 THGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRD 1489
THG NLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHF+ETVSLAG YRD
Sbjct 1436 THGLNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFIETVSLAGMYRD 1495
Query 1490 WSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFT 1549
WSYSGQRTELGVEFLKRGDK+VYHT+ SP++FHLDGEVL LDKLKSLLSLREV+TIKVFT
Sbjct 1496 WSYSGQRTELGVEFLKRGDKVVYHTVGSPIQFHLDGEVLLLDKLKSLLSLREVRTIKVFT 1555
Query 1550 TVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAF 1609
TVDNTNLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH HEGKTFFVLPSDDTLRSEAF
Sbjct 1556 TVDNTNLHTQIVDMSMTYGQQFGPTYLDGADVTKIKPHAKHEGKTFFVLPSDDTLRSEAF 1615
Query 1610 EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNA 1669
EYYHTLDESFLGRYMSALNHTKKWKFPQ+GGLTSIKWADNNCYLSSVLLALQQ+EVKFNA
Sbjct 1616 EYYHTLDESFLGRYMSALNHTKKWKFPQIGGLTSIKWADNNCYLSSVLLALQQIEVKFNA 1675
Query 1670 PALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVC 1729
PALQEAYYRARAGDAANFCALILAYSN+TVGELGDVRETMTHLLQHANLESAKRVLNVVC
Sbjct 1676 PALQEAYYRARAGDAANFCALILAYSNRTVGELGDVRETMTHLLQHANLESAKRVLNVVC 1735
Query 1730 KHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPA 1789
K CGQK+TTLTGVEAVMYMGTLSY+ LKTGV+IPC+CGRDATQYLVQQESSFVMMSAPP+
Sbjct 1736 KTCGQKSTTLTGVEAVMYMGTLSYEELKTGVTIPCICGRDATQYLVQQESSFVMMSAPPS 1795
Query 1790 EYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETS 1849
EY LQQG FLCANEYTG+YQCGHYTH+T KETLYRIDGA+LTKMSEYKGPVTDVFYKE S
Sbjct 1796 EYTLQQGAFLCANEYTGSYQCGHYTHVTVKETLYRIDGAYLTKMSEYKGPVTDVFYKEIS 1855
Query 1850 YTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTC 1909
YTTTIKPVSYKLDGV YTEI+PKLD YYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTC
Sbjct 1856 YTTTIKPVSYKLDGVIYTEIQPKLDEYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTC 1915
Query 1910 SNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVW 1969
SNTKFADDLNQMTGF KPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPI+W
Sbjct 1916 SNTKFADDLNQMTGFKKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIIW 1975
Query 1970 HINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVV 2029
HINQ T KTT+KPNTWCLRCLWSTKPV+TSNSFEVL VEDTQGMDNLACESQ PTSEEVV
Sbjct 1976 HINQTTNKTTYKPNTWCLRCLWSTKPVETSNSFEVLEVEDTQGMDNLACESQTPTSEEVV 2035
Query 2030 ENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNE 2089
ENPTIQKEVIECDVKT EVVGNVILKPS+EGVKVTQELGHEDLMAAYVE TSITIKKPNE
Sbjct 2036 ENPTIQKEVIECDVKTIEVVGNVILKPSEEGVKVTQELGHEDLMAAYVEETSITIKKPNE 2095
Query 2090 LSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYV 2149
LSLALGL+T+ATHG AAINSVPWSKILAYVKPFLGQAA+TT+NC KR QRVFNNYMPYV
Sbjct 2096 LSLALGLRTLATHGAAAINSVPWSKILAYVKPFLGQAAVTTTNCIKRCVQRVFNNYMPYV 2155
Query 2150 FTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMW 2209
TLLFQLCTFT+STNSRIRASLPTTIAKNSVKSVAKLCLD INYVKSPKFSKLFTIAMW
Sbjct 2156 ITLLFQLCTFTRSTNSRIRASLPTTIAKNSVKSVAKLCLDVCINYVKSPKFSKLFTIAMW 2215
Query 2210 LLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICL 2269
LLLLSICLGSLI VTAAFGVLLSN G PSYC+GVRE Y+NSSNVTTMDFCEGSF CS+CL
Sbjct 2216 LLLLSICLGSLIYVTAAFGVLLSNLGIPSYCDGVRESYVNSSNVTTMDFCEGSFLCSVCL 2275
Query 2270 SGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFG 2329
+GLDSLDSYPALETIQVTISSYKLDLT LGLAAEW LAYMLFTKFFYLLGLSAIMQVFFG
Sbjct 2276 NGLDSLDSYPALETIQVTISSYKLDLTSLGLAAEWFLAYMLFTKFFYLLGLSAIMQVFFG 2335
Query 2330 YFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMC 2389
YFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFA YY+WKSYVHIMDGCTSSTCMMC
Sbjct 2336 YFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFAFCYYVWKSYVHIMDGCTSSTCMMC 2395
Query 2390 YKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARD 2449
YKRNRATRVECTTIVNGMKRSFYVYANGGRGFCK HNWNCLNCDTFC GSTFISDEVARD
Sbjct 2396 YKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKAHNWNCLNCDTFCAGSTFISDEVARD 2455
Query 2450 LSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNT 2509
LSLQFKRPINPTDQSSY+VDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNT
Sbjct 2456 LSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNT 2515
Query 2510 KGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFD 2569
KGSLPINVIVFDGKSKCDESA+KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFD
Sbjct 2516 KGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFD 2575
Query 2570 AYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVI 2629
AYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVI
Sbjct 2576 AYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVI 2635
Query 2630 ECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLI 2689
ECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLI
Sbjct 2636 ECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLI 2695
Query 2690 WNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKL 2749
WNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVN ITTKISLKGGKIVST FKL
Sbjct 2696 WNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNAITTKISLKGGKIVSTWFKL 2755
Query 2750 MLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHA 2809
MLKATLLCVLAAL CYI+MPVH+LS+HDGYTNEIIGYKAIQDGVTRDI++TDDCFANKHA
Sbjct 2756 MLKATLLCVLAALFCYIIMPVHSLSVHDGYTNEIIGYKAIQDGVTRDIMATDDCFANKHA 2815
Query 2810 GFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAV 2869
GFD+WFSQRGGSY+NDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAV
Sbjct 2816 GFDSWFSQRGGSYRNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAV 2875
Query 2870 GNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDT 2929
GNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDT
Sbjct 2876 GNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDT 2935
Query 2930 RYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYR 2989
RYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE G+CLSTSGRWVLNNEHYR
Sbjct 2936 RYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEAGVCLSTSGRWVLNNEHYR 2995
Query 2990 ALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFG 3049
AL GVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRR FG
Sbjct 2996 ALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRAFG 3055
Query 3050 EYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMF 3109
EYNHVVAANALLFLMSFTILCL PAYSFLPGVYS+FYLYLTFYFTNDVSFLAHLQWFAMF
Sbjct 3056 EYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYLYLTFYFTNDVSFLAHLQWFAMF 3115
Query 3110 SPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLK 3169
SPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLK
Sbjct 3116 SPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLK 3175
Query 3170 LRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQP 3229
LRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQP
Sbjct 3176 LRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQP 3235
Query 3230 PQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDM 3289
PQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDM
Sbjct 3236 PQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDM 3295
Query 3290 LNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPG 3349
LNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPG
Sbjct 3296 LNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPG 3355
Query 3350 QTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT 3409
QTFSVLACYNGSPSGVYQCAMRPN+TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT
Sbjct 3356 QTFSVLACYNGSPSGVYQCAMRPNYTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT 3415
Query 3410 GVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLND 3469
GVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLND
Sbjct 3416 GVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLND 3475
Query 3470 FNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILED 3529
FNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILED
Sbjct 3476 FNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILED 3535
Query 3530 EFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFL 3589
EFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFL
Sbjct 3536 EFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFL 3595
Query 3590 PFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADT 3649
PFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADT
Sbjct 3596 PFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADT 3655
Query 3650 SLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAIS 3709
SLSGYRLKDCVMYASALVLL+LMTARTVYDDAARRVWTLMNVITLVYKVYYGN+LDQAIS
Sbjct 3656 SLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAIS 3715
Query 3710 MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC 3769
MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC
Sbjct 3716 MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC 3775
Query 3770 YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC 3829
YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC
Sbjct 3776 YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC 3835
Query 3830 IKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMV 3889
IKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMV
Sbjct 3836 IKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMV 3895
Query 3890 SLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
SLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD
Sbjct 3896 SLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3955
Query 3950 SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTM 4009
SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTM
Sbjct 3956 SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTM 4015
Query 4010 LFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYA 4069
LFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYA
Sbjct 4016 LFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYA 4075
Query 4070 SALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQM 4129
SALWEIQQVVDADSKIVQLSEINMDNS NLAWPLIVTALRANSAVKLQNNELSPVALRQM
Sbjct 4076 SALWEIQQVVDADSKIVQLSEINMDNSQNLAWPLIVTALRANSAVKLQNNELSPVALRQM 4135
Query 4130 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4189
SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP
Sbjct 4136 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4195
Query 4190 CRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAF 4249
CRFVTDTP+GPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANS VLSFCAF
Sbjct 4196 CRFVTDTPRGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSAVLSFCAF 4255
Query 4250 AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC 4309
AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC
Sbjct 4256 AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC 4315
Query 4310 HIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQ 4369
HIDHPNPKGFCDLKGKYVQIP TCANDPVGFTL+NTVCTVCG WKGYGCSCDQLREP+MQ
Sbjct 4316 HIDHPNPKGFCDLKGKYVQIPATCANDPVGFTLKNTVCTVCGTWKGYGCSCDQLREPMMQ 4375
Query 4370 SADASTFLN 4378
SADASTFLN
Sbjct 4376 SADASTFLN 4384
>sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 PE=1 SV=1
Length=4405
Score = 7475 bits (19395), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3545/4408 (80%), Positives = 3945/4408 (89%), Gaps = 37/4408 (1%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDA + HGH +VELVAE++GIQYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGK+ CTLSEQLD+I++KRGVYCCR+HEHEIAW
Sbjct 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVASP ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
P NAVVK+ CPAC + E+GPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+Q+S+L+PL F S+A
Sbjct 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
A V+RSIF+RTL+ A +S+ LQ+AA+TILDGIS+ SLRL+DAM++TSDL TN++++MAY
Sbjct 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
+TGG+VQ TSQWL+N+ GT EKL+P+ +W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVC+NGLMLLEIKD E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV EVQGYK+V
Sbjct 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
WS+AT+YLFD++GE +S MYCSFYPPDE+EE+ EEE T ++EYGTEDDYQG
Sbjct 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPST-QYEYGTEDDYQGK 958
Query 961 PLEFGASAETVRVEEEEEEDWLDDTTEQS-------------------EIEP--EPEPTP 999
PLEFGA++ ++ EEE+EEDWLDD ++Q+ E++P E E TP
Sbjct 959 PLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
Query 1000 ---EEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKA 1056
VN F+GYLKLTDNV IK DIV+EA+ P V+VNAAN++LKHGGGVAGALNKA
Sbjct 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
Query 1057 TNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF 1116
TN AMQ ESDDYI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYENF
Sbjct 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
Query 1117 NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPR- 1175
N ++LLAPLLSAGIFGA P+ SL+VCV TVRT VY+AV DK LY+++V +L+ +
Sbjct 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
Query 1176 -----VEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLL 1230
E PK+E P +SK SV Q+ D K KIKAC++EVTTTLEETKFLT LL
Sbjct 1199 VEQKIAEIPKEEVKPFITESK---PSVEQRKQDDK-KIKACVEEVTTTLEETKFLTENLL 1254
Query 1231 LFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLS 1290
L+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML+
Sbjct 1255 LYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLA 1314
Query 1291 RALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWN 1350
+AL+KVP D YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSWN
Sbjct 1315 KALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWN 1374
Query 1351 LREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASI 1410
LREMLAHAEETRKLMP+C++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS+
Sbjct 1375 LREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASL 1434
Query 1411 ITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSS 1470
I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSSS
Sbjct 1435 INTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS 1494
Query 1471 KTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSL 1530
KT EEHF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGEV++
Sbjct 1495 KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVITF 1553
Query 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNH 1590
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH +H
Sbjct 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSH 1613
Query 1591 EGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN 1650
EGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNN
Sbjct 1614 EGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNN 1673
Query 1651 CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMT 1710
CYL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM+
Sbjct 1674 CYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMS 1733
Query 1711 HLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDA 1770
+L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+ A
Sbjct 1734 YLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQA 1793
Query 1771 TQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHL 1830
T+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA L
Sbjct 1794 TKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALL 1853
Query 1831 TKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPID 1890
TK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPID
Sbjct 1854 TKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPID 1913
Query 1891 LVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYR 1950
LVP QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY+
Sbjct 1914 LVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYK 1973
Query 1951 HYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDT 2010
HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1974 HYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDA 2033
Query 2011 QGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHE 2070
QGMDNLACE +P SEEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+GH
Sbjct 2034 QGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHT 2093
Query 2071 DLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITT 2130
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + TT
Sbjct 2094 DLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTT 2153
Query 2131 SNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
+N R RV NYMPY FTLL QLCTFT+STNSRI+AS+PTTIAKN+VKSV K CL+A
Sbjct 2154 TNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEA 2213
Query 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNS 2250
NY+KSP FSKL I +W LLLS+CLGSLI TAA GVL+SN G PSYC G RE YLNS
Sbjct 2214 SFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNS 2273
Query 2251 SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYML 2310
+NVT +C GS PCS+CLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+L
Sbjct 2274 TNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYIL 2333
Query 2311 FTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYI 2370
FT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY+
Sbjct 2334 FTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYV 2393
Query 2371 WKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCL 2430
WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC+
Sbjct 2394 WKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCV 2453
Query 2431 NCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTY 2490
NCDTFC GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV VKNG++HLYFDKAGQKTY
Sbjct 2454 NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTY 2513
Query 2491 ERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLD 2550
ERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES++KSASVYYSQLMCQPILLLD
Sbjct 2514 ERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLD 2573
Query 2551 QALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTF 2610
QALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF
Sbjct 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
Query 2611 VSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACID 2670
+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACID
Sbjct 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACID 2693
Query 2671 CNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNV 2730
C+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV
Sbjct 2694 CSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNV 2753
Query 2731 ITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
+TTKI+LKGGKIV+ K ++K TL+ + A + Y++ PVH +S H +++EIIGYKAI
Sbjct 2754 VTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAID 2813
Query 2791 DGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTV 2850
GVTRDI STD CFANKHA FD WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT+
Sbjct 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTI 2873
Query 2851 LRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYC 2910
LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYC
Sbjct 2874 LRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC 2933
Query 2911 YDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE 2970
YDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2934 YDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
Query 2971 VGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGII 3030
G+C+STSGRWVLNN++YR+L GVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+
Sbjct 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
Query 3031 AILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLT 3090
AI+VTC AYYFM+FRR FGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYSV YLYLT
Sbjct 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
Query 3091 FYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFS 3150
FY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNGV+FS
Sbjct 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFS 3173
Query 3151 TFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCH 3210
TFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCH
Sbjct 3174 TFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCH 3233
Query 3211 LAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3270
LAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL
Sbjct 3234 LAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
Query 3271 WLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLK 3330
WLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LK
Sbjct 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
Query 3331 VDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGF 3390
VDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGF
Sbjct 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
Query 3391 NIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA 3450
NIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYA
Sbjct 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
Query 3451 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKE
Sbjct 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
Query 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLI 3570
LLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+
Sbjct 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
Query 3571 LVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMV 3630
LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMV
Sbjct 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
Query 3631 YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMN 3690
YMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMN
Sbjct 3654 YMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMN 3713
Query 3691 VITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
V+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITG
Sbjct 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
Query 3751 NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKS 3810
NTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+
Sbjct 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
Query 3811 SIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3870
SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ
Sbjct 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
Query 3871 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPS 3930
LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPS
Sbjct 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPS 3953
Query 3931 YAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 3990
YAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY
Sbjct 3954 YAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 4013
Query 3991 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4050
KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV
Sbjct 4014 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4073
Query 4051 VPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA 4110
+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRA
Sbjct 4074 IPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 4133
Query 4111 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKW 4170
NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLKW
Sbjct 4134 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKW 4193
Query 4171 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4230
ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ
Sbjct 4194 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4253
Query 4231 AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4290
AGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE
Sbjct 4254 AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
Query 4291 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 4350
ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVC
Sbjct 4314 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVC 4373
Query 4351 GMWKGYGCSCDQLREPLMQSADASTFLN 4378
GMWKGYGCSCDQLREP++QSADA +FLN
Sbjct 4374 GMWKGYGCSCDQLREPMLQSADAQSFLN 4401
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 6150 bits (15955), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3335/7275 (46%), Positives = 4538/7275 (62%), Gaps = 346/7275 (5%)
Query 13 HVQLSLPVLQVRDVLVR---GFGDSVEEALSEAREHLKNGTCGLV--ELEKGVLPQLEQP 67
HV L + D++++ F D E A E L G+ L + KG + L P
Sbjct 28 HVSLKASLCDAGDLVLKISPWFMDG-ESAYKHVSEQLSKGSKLLFVPQTLKGFIRHLPGP 86
Query 68 YVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITL-----GVLVPHVGETPIAYRNVL 122
V++ T +V +A + G G TL G+ P + L
Sbjct 87 RVYLVERLTGGTYSDPFMVNQLAYQNAAGEGVIGTTLQGKRVGMFFPFDADLVTGEFQFL 146
Query 123 LRKNGNKGAGGHSYGIDLKSY------DLGDELGTDPIEDYEQNWNTKHGSGALRELTRE 176
LRK KG GG+ + Y DL D L DP Y Q+ L ++
Sbjct 147 LRK---KGFGGNRFRDAPWDYNWTPYSDLMDALEADPCGKYSQS------------LLKK 191
Query 177 LNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAG--KSMCTLSEQLDYIESKRGVYCCRDH 234
L GG T +D CG +G P+ +A G K +E +S R + ++
Sbjct 192 LVGGDFTP-IDQYMCGKNGKPIAEFAALMASEGITKLADVEAEVKSRTDSDRYI-VFKNK 249
Query 235 EHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTE 294
+ I W +R D +Y Q+ F + S + DT + + P+ F + S+++VI P +
Sbjct 250 LYRIVWNVQRKDVAYSKQSAFTMNSIVQLDTME-DVPRHSFTIGSEIQVIAPSTAVQANG 308
Query 295 GFMGRIRSVYPVASPQ---ECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVI 351
+ R +Y Q E N ++ S + C C + SW T + ++ CG
Sbjct 309 HLNLKQRLLYAFYGKQAVSEPNYIYHSAYVDCTSCGKGSWLTGNAVQGFACDCGAHYCAN 368
Query 352 E-GPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRT--RCFGG 408
+ + G + NAV+ CP +D E +H++ + + + G+T +GG
Sbjct 369 DVDLQSSGLVRKNAVLLTTCPCNKDGEC--KHTLPQLVSMMTDKCDVEVVGKTFILTYGG 426
Query 409 CVFAYVGCYNKRAYWVPRASA-------DIGSGHTGITGDNVETLNEDLLEILSRERVNI 461
++AY+GC +++PRA + I +G TG ET N L R + I
Sbjct 427 VIYAYMGCSGGTMHFIPRAKSCVSKIGDAIFTGCTGTWSKVCETANL----FLERAQHAI 482
Query 462 NIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAW 521
N V +F L E V +L+ ++S D ++ ++ + + G + VT G ++G
Sbjct 483 NFVNEFVLTETVVALLSGTTSSIEELRDLCRNATFEKVRDYLTPRG-WIVTMGSYIEGVI 541
Query 522 NIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLV 581
N+G +C A ++ S + + L + LD ++ V
Sbjct 542 NVGA-----AGVCNAALNAPFIVLSGLGESFKKVAATPWKLCSSLRETLDHYADSITYRV 596
Query 582 -------DAMVYTSDLLTNSVII--MAYVTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIE 632
D YT+ LL +V+ AY V + + L+NL+ ++ + F ++
Sbjct 597 FPYDIPCDVTDYTALLLDCAVLTGASAYFVARYVDEKVEQLTNLVFSSCQSAVAAF--VQ 654
Query 633 AKLS---AGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMC 689
A +S A +F+ D + ++K + ++ V D +K F+ +++KA+++
Sbjct 655 ACMSTYKATAKFISDMFTLIKVVSERLYVYTSVGFVVVGDYSSQLLKQFMHILSKAMQLL 714
Query 690 IDQVTIAGAKLRSL--NLGEVFIAQSKGLYRQCIRGK---EQLQLLMPLK-APKEVTFLE 743
V+ AG+KL S+ N + + S Y +G+ +Q L++P + K++ LE
Sbjct 715 HTTVSWAGSKLPSVVYNGRDSLVFPSGTYYCVSTQGRSLQDQFDLVIPGDLSKKQIGILE 774
Query 744 GDSHDTVLTSE------EVVLKNGELEALETPVDSFTNGAIVGTPVCV-NGLMLLEIKDK 796
+ T + + EVV+ G+LE P + +VG V + N + + ++D
Sbjct 775 PTPNSTTVDKKINTNVVEVVV--GQLE----PTKEHSPELVVGDYVIISNKIFVRSVEDS 828
Query 797 EQ--YCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDERVDKVL 854
E Y + G + +FRLKGGAP KGV FG + E+ ++V + +++ +D +L
Sbjct 829 ETVFYPLCTDGKIVPT-LFRLKGGAPPKGVKFGGEQTKEITAVRSVSVDYDVHPVLDALL 887
Query 855 -NEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAG 913
+ + +TVE V +F VV + V++ L + G DL++++ Y+++ G
Sbjct 888 AGSELATFTVEKDLPVKDFVDVVKDEVIELLSKLLRGYNVDGFDLEDFADTPCYVYNAEG 947
Query 914 EENFSSRMYCSFYPPDEEEE--DDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETV 971
+ +SS M S P +E EE DD E+E + E E E+D + A+ E V
Sbjct 948 DLAWSSTMTFSVNPVEEVEEECDDDYVEDEYLSE----EMLVEEDEN----SWAAAVEAV 999
Query 972 RVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSAN 1031
E+ + D L + SE P + V + T+ V + +++ +Q AN
Sbjct 1000 IPMEDVQLDTLVAEIDVSE--------PADDVAEQAS----TEEVEVPSACVLEASQVAN 1047
Query 1032 PMVIVN-----AANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGH 1086
+ + +++I L A A + A ++ KL+ VG
Sbjct 1048 AAEVESCEAEVSSSIPLHEDANAAKANDCAEGMPALDSTETVSKLSVDTPVG-------- 1099
Query 1087 NLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQT 1146
V + + + + + +S+ ++ P + P ++L V+
Sbjct 1100 -------DVTQDDATSSNATVISEDVHTATHSKGLVAVPEVV-------PEKALGTSVER 1145
Query 1147 VRTQVYIAVNDKALYEQ--VVMDYLDNLKP-RVEAPKQEEPPNTEDSKTEEKSVVQKPVD 1203
+R+ V + +L ++ V++ + KP RV+ PK E P V D
Sbjct 1146 MRSTSEWTVVETSLKQETAVIVKNDSSAKPQRVKKPKAENPLKNFKHIVLNNDVTLVFGD 1205
Query 1204 VKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMV 1263
+A D + T L I + S +++ E ++ P V
Sbjct 1206 AIAVARATEDCILVNAANTH-----LKHGGGIAAAIDRASGGLVQAESDDYVNFYGPLNV 1260
Query 1264 GDVIT------SGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEE 1317
GD + I VV P +A ++L R K ++Y AG E
Sbjct 1261 GDSTLLKGHGLATGILHVVGPDARANQDIQLLKRCYKAF--NKYPLVVSPLISAGIFCVE 1318
Query 1318 AKTALKKCKSA-----FYVLPSE-------APNAKEEI-LGTVSWNLREMLAHAEETRKL 1364
+ +L+ S + V+ SE AP + W R ++ +A+
Sbjct 1319 PRVSLEYLLSVVHTKTYVVVNSEKVYNDLAAPKPPTGLTYSHEGW--RGIIRNAKSFGFT 1376
Query 1365 MPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTM 1424
IC D A ++ + + + VD GV+++ Y+SK+P+ IIT N+ + + M
Sbjct 1377 CFICTDQSANAKLLKGRGVDLTKKTQTVD-GVKYYLYSSKDPLTDIITAANAC-KGICAM 1434
Query 1425 PIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLA 1484
PIGYVTHG +L +A + ++ + P V ++S D V N + + +T E+ F+ TV
Sbjct 1435 PIGYVTHGLDLAQAGQQVKKITVPYVCLLASKDQVPILNSDV--AVQTPEQSFINTVIAN 1492
Query 1485 GSYRDWSY-SGQRTELGVEF---LKRGDKIV------YHTLESPVEFHLDGEVLSLDKLK 1534
G Y W +G+ GV + L D+ + ++ ++ + D SL+K +
Sbjct 1493 GGYHCWHLVTGELIVKGVSYRKLLNWSDQTICYADNKFYVVKGQIALPFD----SLEKCR 1548
Query 1535 SLLSLR--EVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEG 1592
+ L+ R + K + V T+D N T +++ + TY Q G + G+D++ P G
Sbjct 1549 TYLTSRAAQQKNVDVLVTIDGVNFRTVVLNNTTTYRVQLGSVFYKGSDISDTIPTEKMSG 1608
Query 1593 KTFFVLPSDDTLRSEAF---EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADN 1649
+ ++ +D+ +E E Y T D +FL RY S L KKWK+ G+ S+K N
Sbjct 1609 EAVYL--ADNLSEAEKAVLSEVYGTADTAFLHRYYSLLALVKKWKYTVHDGVKSLKLNSN 1666
Query 1650 NCYLSSVLLALQQL-EVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRET 1708
NCY++ +L L L E+KF PALQ AY + + GD+ F ALI+AY + T GE D
Sbjct 1667 NCYVNVTMLMLDMLKEIKFIVPALQAAYLKHKGGDSTEFIALIMAYGDCTYGEPDDASRL 1726
Query 1709 MTHLLQHANLES-AKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCG 1767
+ +L A L + AK V C CG + TT TG++A +Y+G S D L C CG
Sbjct 1727 LHTILSKAELTTQAKMVWRQWCNVCGVQDTTTTGLKACIYVGMNSLDELHATHEECCQCG 1786
Query 1768 RDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTG-------NYQCGHYTHITAKE 1820
+ LV+ + ++++S + + +YT GHY H+ K+
Sbjct 1787 DVRKRQLVEHNAPWLLLSGLNEAKVMTPTSQSAGPDYTAFNVFQGVETSVGHYLHVRVKD 1846
Query 1821 TL-YRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKK 1879
L Y+ D L+K S+ K +TDV+Y + Y+ V Y LDG T+ +++P L +Y K
Sbjct 1847 NLLYKYDSGSLSKTSDMKCKMTDVYYPKQRYSADCNVVVYSLDGNTWADVDPDLSAFYMK 1906
Query 1880 DNAYYTEQP-IDLVPTQPLPNASFDNFKL-----TCSNTKFADDLNQMTGF--TKPASRE 1931
D Y+T++P I+ P L + + N L T + + N + GF +KP S++
Sbjct 1907 DGKYFTKKPVIEYSPATILSGSVYTNSCLVGHDGTIGSDAISSSFNNLLGFDNSKPVSKK 1966
Query 1932 LSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLW 1991
L+ +FFPD GDV+ +Y Y +K GA L KPI+W N K N LR ++
Sbjct 1967 LTYSFFPDFEGDVILTEYSTYDPIYKNGAMLHGKPILWVNNSKFDSALNKFNRATLRQVY 2026
Query 1992 STKPVDTSNSFEVLAVEDTQGMDNLAC-ESQQPTSE-EVVENPTIQKEVIECD-VKTTEV 2048
PV N + VL Q ++ A E +P S +V E+ + +I+C +K V
Sbjct 2027 DIAPVTLENKYTVLQDNQIQQVEVEAPKEDAKPQSPVQVAEDIDNKLPIIKCKGLKKPFV 2086
Query 2049 VGNVILKPSDEGVKVTQELGHEDLMAAYVE-NTSITIKKPNELSLALGLKTIATHG---I 2104
+GV V LG +DL A YV+ N + + K N S + T+ I
Sbjct 2087 KDGYSFVNDPQGVNVIDTLGIDDLRALYVDRNLRLIVLKENNWSALFNIHTVEKGDLSVI 2146
Query 2105 AAINSVPWS-KILAYVKPFLGQAAITTSNCAK-------RLAQRVFNN--YMPYVFTLLF 2154
AA S+ KIL Q A T N R+ + V N + F LL
Sbjct 2147 AASGSITRRVKILLGASSLFAQFASVTVNVTTAMGKALGRMTRNVITNTGIIGQGFALLK 2206
Query 2155 QLC----TFTKSTN-SRIRASLPTTIAKNSVKS-VAKLCLDAGINYVKSPKFSKLFTIAM 2208
L TF KS N S ++ + V + V K C A + V KF ++ +
Sbjct 2207 MLLILPFTFWKSKNQSTVKVEVGALRTAGIVTTNVVKQCASAAYD-VLVVKFKRIDWKST 2265
Query 2209 WLLLLSIC------------------LGSLICVTAAFGVLL------SNFGAPSYCNGVR 2244
LL IC L S + + A G+L S G S C+G+
Sbjct 2266 LRLLFLICTTGLLLSSLYYLFLFHQVLTSDVMLDGAEGMLATYRELRSYLGIHSLCDGMV 2325
Query 2245 ELYLNSSNVTTMDFCEG-SFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAE 2303
E Y N S DFC S C+ CL G DSL Y A + IQ ++SY +++ + E
Sbjct 2326 EAYRNVS-YDVNDFCSNRSALCNWCLIGQDSLTRYSAFQMIQTHVTSYVINIDWVWFVME 2384
Query 2304 WVLAYMLFTKFFYLLGLSAIMQVFFGYFAS--HFISNSWLMWFIISIVQMAPVSAMVRMY 2361
+ LAY+L+T F +L L Q FF Y + ++ S ++L+ V P+ +VR+Y
Sbjct 2385 FALAYVLYTSTFNVLLLVVSSQYFFSYTGAFVNWRSYNYLVSGYFFCVTHIPLLGLVRIY 2444
Query 2362 IFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGF 2421
F A +++ + Y H+++GC + C++CYKRNR TRVE +T+V G KR+FY+ ANGG F
Sbjct 2445 NFLACLWFLRRFYNHVINGCKDTACLLCYKRNRLTRVEASTVVCGSKRTFYIVANGGTSF 2504
Query 2422 CKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLY 2481
C HNWNC++CDT G+TFI +EVA DL+ +R + PTD+S Y V+SV VK+ + L+
Sbjct 2505 CCRHNWNCVDCDTAGIGNTFICEEVANDLTTSLRRLVKPTDKSHYYVESVTVKDSVVQLH 2564
Query 2482 FDKAGQKTYERHPLSHFVNLDNLRAN---NTKGSLPI-NVIVFDGKSKCDESASKSASVY 2537
+ + G YER+PL +F NLD L+ T +P N +++D + E+ ++SA VY
Sbjct 2565 YSREGASCYERYPLCYFTNLDKLKFKEVCKTPTGIPEHNFLIYDSSDRGQENLARSACVY 2624
Query 2538 YSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSEL 2597
YSQ++ +P+LL+D +V+ VGDS E++ KM D+YV++F + F V +KL LVATA +
Sbjct 2625 YSQVLSKPMLLVDSNMVTTVGDSREIASKMLDSYVNSFISLFGVNRDKLDKLVATARDCV 2684
Query 2598 AKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNK 2656
+G V+ TF AAR V++DV+T +++ L+ ++ DL++T + NN++ +Y K
Sbjct 2685 KRGDDFQTVIKTFTDAARGPAGVESDVETSSIVDALQYAYKHDLQLTTEGFNNYVPSYIK 2744
Query 2657 VENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIP 2716
+++ DLG ID NA +N ++ N + IWN DYM LS+ L++QIR A +K NIP
Sbjct 2745 PDSVATADLGCLIDLNAASVNQTSIRNANGACIWNSSDYMKLSDSLKRQIRIACRKCNIP 2804
Query 2717 FRLTCATTRQVVNVITTKIS---LKGG------KIVSTCFKLMLKATLLCVLAALVCYIV 2767
FRLT + R N+++ K S L GG K+ +K TL+ A++ Y+
Sbjct 2805 FRLTTSRLRSADNILSVKFSATKLSGGAPKWLLKLRDFTWKSYCVVTLVVFAMAVLSYLC 2864
Query 2768 MPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQR-GGSYKNDK 2826
+P +S + + I+ YK +++G+ RDI +D CFANK+ F WF++ GG + ND
Sbjct 2865 LPAFNMSQVSFHEDRILTYKVVENGIIRDITPSDTCFANKYQSFSKWFNEHYGGLFNNDI 2924
Query 2827 SCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFA 2886
SCPV A+I G VP LP V + + F+ RVF++ N+CYTP+ I Y F+
Sbjct 2925 SCPVTVAVIAGVAGARVPNLPANV-AWVGRQIVLFVSRVFASSNNVCYTPTAEIPYERFS 2983
Query 2887 TSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSI-IQFPNTY 2945
S CVLA+ECT+F+DA GK PYCYD +L G+ +Y +++P RY + D + I+FP
Sbjct 2984 DSGCVLASECTLFRDAEGKINPYCYDPTVLPGASAYDQMKPHVRYDMYDSDMYIKFPEVV 3043
Query 2946 LEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIA 3005
E ++R+ T YCR G+CE + G+C++T+G W + N+HY GV+CG + +++
Sbjct 3044 FESTLRITKTLATRYCRFGSCEDANEGVCITTNGSWAIYNDHYANKPGVYCGDNYFDIVR 3103
Query 3006 NIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMS 3065
+ L QPV +S S+ G ++ I +T A YY K +R +Y L++
Sbjct 3104 RLGLSLFQPVTYFQLSTSLALGVMLCIFLTIAFYYVNKVKRALADYTQCAVVAVAAALLN 3163
Query 3066 FTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCI 3125
LC V + L Y+ Y Y TFY T + +F+ H+ WF MF +VP W+ Y+ +
Sbjct 3164 SLCLCFVVSNPLLVLPYTALYYYATFYLTGEPAFVMHVSWFVMFGTVVPIWMVFAYIVGV 3223
Query 3126 SLKHCHWFFNNYLRK--RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNR 3183
L+H W + +K V +G +F++AA F++NK+ Y+ LR+ + YNR
Sbjct 3224 CLRHLLWVMAYFSKKHVEVFTDGKLNCSFQDAAANIFVINKDTYVALRNS--ITQDSYNR 3281
Query 3184 YLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGF 3243
YL+++NKYKY+SGA+DT SYREA+ HL KAL +S +G+DVL+QPP S+TS+VLQSG
Sbjct 3282 YLSMFNKYKYYSGAMDTASYREASAAHLCKALQVYSETGSDVLFQPPNCSVTSSVLQSGL 3341
Query 3244 RKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSN 3303
KMA PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C A+ + +PNY+ LL+ K+N
Sbjct 3342 VKMAAPSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDALLVSKTN 3401
Query 3304 HSFLVQ---AGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
SF+VQ LRV+GH+M LL+L V+++NP+TP Y F ++PG +FSVLACYNG
Sbjct 3402 LSFIVQKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFSVLACYNG 3461
Query 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
P+GV+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H G +G
Sbjct 3462 RPTGVFMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHTGCAFDGV 3521
Query 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY- 3479
YG F DRQ Q +D T+N++AWLYAA++NG WF+ T + FN AM +
Sbjct 3522 MYGAFEDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEWAMSNQFT 3581
Query 3480 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3539
E + VD+L + +TG++V + A+ + L G G+TILG+++LEDEFTP DV Q
Sbjct 3582 EFIGTQSVDML---AHKTGVSVEQLLYAI-QTLHKGFQGKTILGNSMLEDEFTPDDVNMQ 3637
Query 3540 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIA 3599
GV Q K+I G HW+ T L + + +Q T+++++ +++E L T ++ +
Sbjct 3638 VMGVVMQSGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLTPLVLCVM 3697
Query 3600 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLELADTSLSGYR 3655
AC ML VKHKH FL LFLLP+ + Y N+VY P +S ++ + WL A +
Sbjct 3698 ACVMLTVKHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPASVYMRTTH 3757
Query 3656 LKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVI 3715
D +Y S L ++ R +A+ L + + Y G+ ++ +
Sbjct 3758 -TDLGVYLSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPLTYLMFLT 3815
Query 3716 SVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
++TS+Y+ V + +A+ V Y P ++ ++L+Y +GY C YFG+F
Sbjct 3816 TLTSDYTVTVFLAVNVAKFFARVVFLYAPHAGFIFPEVKLVLLMYLAVGYFCTVYFGVFS 3875
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
LLN R+ LGVYDY VSTQEFRY+ GL P++S +A +LN+KL+GIGG PCIK+A+V
Sbjct 3876 LLNLKLRVPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTPCIKIASV 3935
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK++D+KCTSVVLLSVLQQL +E++SK WA CV+LHNDIL A D TEAF+ V L + L
Sbjct 3936 QSKLTDLKCTSVVLLSVLQQLHLEANSKAWAHCVKLHNDILAATDPTEAFDNFVCLFATL 3995
Query 3896 LSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVL 3954
+S VD+ L ++LD+ + LQA SEFS L SYA AQ +Y++A+ +GD S VL
Sbjct 3996 MSFSANVDLEALASDLLDHPSVLQATLSEFSHLASYAELEAAQSSYQKALNSGDASPQVL 4055
Query 3955 KKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTML 4014
K L+K++N+AK+ +++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M+
Sbjct 4056 KALQKAVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMI 4115
Query 4015 RKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWE 4074
+KLDND LN +I+NAR+GCVPL+++PL + KL VV+PD + + +YA ALW+
Sbjct 4116 KKLDNDVLNGVISNARNGCVPLSVVPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWD 4175
Query 4075 IQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA-NSAVKLQNNELSPVALRQMSCAA 4133
I + + D ++V+ S++ N +L WPL++ RA +SAV LQNNE+ P L+ M +A
Sbjct 4176 ISLINNVDGEVVKSSDVTETNE-SLTWPLVLECTRAASSAVTLQNNEIRPSGLKTMVVSA 4234
Query 4134 GTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFV 4193
G C + ++LAYY +G + ++ +LS++ LKWA+ DG I EL+PPC+F+
Sbjct 4235 GIDHANC-NTSSLAYYEPVEGRKMLMGILSENAHLKWAKVEGRDGFVNI--ELQPPCKFL 4291
Query 4194 TDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDP 4253
PKGP+V+YLYF+K LNNL+RG +LG +AATVRLQAG+ TE NS+VLS F+VDP
Sbjct 4292 IAGPKGPEVRYLYFVKNLNNLHRGQLLGHIAATVRLQAGSNTEFAINSSVLSAVTFSVDP 4351
Query 4254 AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDH 4313
KAY D++ +GG P+TNCVKML TGTG A++V PEAN DQ+++GGAS CLYCR HI+H
Sbjct 4352 GKAYLDFVNAGGAPLTNCVKMLTPKTGTGIAVSVKPEANADQDTYGGASVCLYCRAHIEH 4411
Query 4314 PNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADA 4373
P+ G C KGK+VQ+P DPVGF L+NT C VC W G+GC+CD LR + +
Sbjct 4412 PDVTGVCKFKGKFVQVPLH-IRDPVGFCLQNTPCNVCQFWIGHGCNCDALRGTTIPQSKD 4470
Query 4374 STFLNRVCG-VSAARLTPCGTGTSTDVVYRAFDI--YNEKVAGFAKFLKTNCCRFQEKDE 4430
S FLNRV G + AR+ PC +G +TDVV+RAFDI Y KVAG K+ KTN CRF E D+
Sbjct 4471 SNFLNRVRGSIVNARIEPCASGLTTDVVFRAFDICNYKAKVAGIGKYYKTNTCRFVEVDD 4530
Query 4431 EGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTK 4490
EG+ LDS+FVVKRHTM NY+ E+ Y+LVKDC AVAVHDFF F VD PHI RQRLT+
Sbjct 4531 EGHRLDSFFVVKRHTMENYELEKRCYDLVKDCDAVAVHDFFIFDVDKVKTPHIVRQRLTE 4590
Query 4491 YTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGER 4550
YTM DLVYALRHFD+ NC+ LK ILV Y CCD YF+ K W+DFVENP+++ VY LGER
Sbjct 4591 YTMMDLVYALRHFDQNNCEVLKSILVKYGCCDASYFDNKLWFDFVENPNVISVYHKLGER 4650
Query 4551 VRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLL 4610
+RQ++L TV+FCD M +G+VGVLTLDNQDLNG WYDFGDFV PG GV IVDSYYS L
Sbjct 4651 IRQAVLNTVKFCDQMVKSGLVGVLTLDNQDLNGKWYDFGDFVITQPGAGVAIVDSYYSYL 4710
Query 4611 MPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINC 4670
MP+L++T LAAE+H D DL KPLI+W LL+YD+T+ ++ LF++YFK WDQ YHPNC+NC
Sbjct 4711 MPVLSMTNCLAAETHRDCDLTKPLIEWPLLEYDYTDYKIGLFEKYFKXWDQQYHPNCVNC 4770
Query 4671 LDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNL 4730
DDRC+LHCANFNVLFS P TSFGP+VRKIFVDGVPFV+S GYH++ELG+V N DV+L
Sbjct 4771 TDDRCVLHCANFNVLFSMTLPGTSFGPIVRKIFVDGVPFVISCGYHYKELGLVMNMDVSL 4830
Query 4731 HSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYD 4790
H RLS KEL++YAADPAMH AS + L D RT CFSVAALT + FQTV+PGNFNKDFYD
Sbjct 4831 HRHRLSLKELMMYAADPAMHIASASALWDLRTPCFSVAALTTGLTFQTVRPGNFNKDFYD 4890
Query 4791 FAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFD 4850
F VSKGFFKEGSSV L+HFFFAQDG+AAI+DY YY YNLPTMCDI+Q+LF +EVVD+YF+
Sbjct 4891 FVVSKGFFKEGSSVTLRHFFFAQDGHAAITDYSYYAYNLPTMCDIKQMLFCMEVVDRYFE 4950
Query 4851 CYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQ 4910
YDGGC+NA++VIVNNLDKSAG PFNK+GKAR+YY+S+SY++QD LFA TKRNV+PTITQ
Sbjct 4951 IYDGGCLNASEVIVNNLDKSAGHPFNKFGKARVYYESLSYQEQDELFAMTKRNVLPTITQ 5010
Query 4911 MNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNM 4970
MNLKYAISAKNRARTVAGVSI STMTNRQ+HQK+LKS+AATRG+T VIGT+KFYGGW M
Sbjct 5011 MNLKYAISAKNRARTVAGVSILSTMTNRQYHQKMLKSMAATRGSTCVIGTTKFYGGWDFM 5070
Query 4971 LKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQ 5030
LKT+Y DV+ PHLMGWDYPKCDRAMPNM RI ASL+LARKH+TCC + RFYRLANECAQ
Sbjct 5071 LKTLYKDVDNPHLMGWDYPKCDRAMPNMCRIFASLILARKHSTCCTNTDRFYRLANECAQ 5130
Query 5031 VLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVR 5090
VLSE V+CGG YVKPGGTSSGDATTAYANSVFNI QA TANV+AL+ +GN I D+ V+
Sbjct 5131 VLSEYVLCGGGYYVKPGGTSSGDATTAYANSVFNILQATTANVSALMGANGNTIVDEEVK 5190
Query 5091 NLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKN 5150
++Q LY +YR D +FVD +YA+L KHFSMMILSDD VVCYNS+YA +G +ASI+N
Sbjct 5191 DMQFELYVNVYRKSQPDPKFVDRYYAFLNKHFSMMILSDDGVVCYNSDYATKGYIASIQN 5250
Query 5151 FKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAG 5210
FK LYYQNNVFMSEAKCW ETDL KGPHEFCSQHT+ +K GDD +LPYPDPSRIL AG
Sbjct 5251 FKETLYYQNNVFMSEAKCWVETDLKKGPHEFCSQHTLFIKDGDDGYFLPYPDPSRILSAG 5310
Query 5211 CFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLD 5270
CFVDDIVKTDGTLM+ERFVSLAIDAYPLTKH + EY +VF +YLQYI KL+ +LTGHMLD
Sbjct 5311 CFVDDIVKTDGTLMVERFVSLAIDAYPLTKHDDPEYQNVFWVYLQYIEKLYKDLTGHMLD 5370
Query 5271 MYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKC 5330
YSVML DN++++WE FY +YT T LQAVG+CV+C+SQTSLRCG CIRRPFLCCKC
Sbjct 5371 SYSVMLCGDNSAKFWEESFYRDLYTAPTTLQAVGSCVVCHSQTSLRCGTCIRRPFLCCKC 5430
Query 5331 CYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQV 5390
CYDHVI+T HK+VLSV+PYVCNAPGCDV DVT+LYLGGMSY+C H+P SFPLCANG V
Sbjct 5431 CYDHVIATPHKMVLSVSPYVCNAPGCDVADVTKLYLGGMSYFCIDHRPVCSFPLCANGLV 5490
Query 5391 FGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSY 5450
FGLYKN C GS +VT+FN +ATCDWT +GDY LANT TE LKLFAAETL+ATEE K SY
Sbjct 5491 FGLYKNMCTGSPSVTEFNRLATCDWTESGDYTLANTTTEPLKLFAAETLRATEEASKQSY 5550
Query 5451 GIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAV 5510
IAT++E++ +REL L WE GK +PPLNRNYVFTGY +TKNSKVQ+GEY FE+ DY DAV
Sbjct 5551 AIATIKEIVGERELLLVWEAGKAKPPLNRNYVFTGYHITKNSKVQLGEYVFERIDYSDAV 5610
Query 5511 VYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANY 5570
Y+ +TTYKL VGD FVLTSH+V L APT+V QE YV+ITGLYPTL + +EF+++VAN+
Sbjct 5611 SYKSSTTYKLAVGDIFVLTSHSVATLQAPTIVNQERYVKITGLYPTLTVPEEFANHVANF 5670
Query 5571 QKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDK 5630
QK G K+ T+QGPPGTGKSHFAIGLA+YYP+AR+VYTACSHAAVDALCEKA KYL I K
Sbjct 5671 QKAGFSKFVTVQGPPGTGKSHFAIGLAIYYPTARVVYTACSHAAVDALCEKAFKYLNIAK 5730
Query 5631 CSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNA 5690
CSRIIPA+ARVEC+D+FKVN T QY+F T+NALPET+ADI+V DE+SM TNYDLSV+NA
Sbjct 5731 CSRIIPAKARVECYDQFKVNETNSQYLFSTINALPETSADILVVDEVSMCTNYDLSVINA 5790
Query 5691 RLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIV 5750
R++AKH VY+GDPAQLPAPRTLLT+GTLEPE FNSV RLM +GPD+FL C RCP EIV
Sbjct 5791 RIKAKHIVYVGDPAQLPAPRTLLTRGTLEPENFNSVTRLMCNLGPDIFLSVCYRCPEEIV 5850
Query 5751 DTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKA 5810
+TVSALVY+NKL A K S QCFK+ YKG +THD SSAINRPQ+ V+ F+ NP W KA
Sbjct 5851 NTVSALVYNNKLVAKKPASGQCFKILYKGSVTHDASSAINRPQLNFVKSFIAANPNWSKA 5910
Query 5811 VFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAK 5870
VFISPYNSQNAVA +LGL TQTVDSSQGSEY YVIF QT +TAH+ N+NRFNVA+TRA+
Sbjct 5911 VFISPYNSQNAVARSVLGLTTQTVDSSQGSEYPYVIFCQTADTAHANNINRFNVAVTRAQ 5970
Query 5871 IGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLS 5930
GILC+M+ + L+D L+F + + N LQ++ VTGL+KDCS+ +GLHP APT++S
Sbjct 5971 KGILCVMTSQALFDSLEFAEVSL---NNYKLQSQIVTGLYKDCSRESSGLHPAYAPTYVS 6027
Query 5931 VDIKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWI 5989
VD K+KT + LCV++ +P ++ Y R+IS MGFK++ + YP +FITR+EAIR VR+WI
Sbjct 6028 VDDKYKTSDELCVNL-NVPANVPYSRVISRMGFKLDASIPNYPKLFITRDEAIRQVRSWI 6086
Query 5990 GFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFK 6049
GFDVEG HA+R+A GTN+PLQLGFSTGVN V P G VDTE + T + A+PPPG+QFK
Sbjct 6087 GFDVEGAHASRNACGTNVPLQLGFSTGVNFVVQPVGVVDTEWGSMLTSIAARPPPGEQFK 6146
Query 6050 HLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTC 6109
HL+PLM KG W +VR +IVQMLSDTL LSD FV WAHGFELTS YF KIG E+ C
Sbjct 6147 HLVPLMNKGAAWPIVRRRIVQMLSDTLDKLSDYCTFVCWAHGFELTSASYFCKIGKEQRC 6206
Query 6110 CLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNA 6169
C+C++RA+ +S+ +YACW+HS G+DYVYNPF +DVQQWG+ GNL +NHD++C VH A
Sbjct 6207 CMCNRRASTYSSPLHSYACWSHSSGYDYVYNPFFVDVQQWGYIGNLATNHDRYCSVHQGA 6266
Query 6170 HVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFP 6229
HVAS DA+MTRCLA+H+CF++RV+W + YP I E R+NS CR V+ VV++ALLA +F
Sbjct 6267 HVASNDAVMTRCLAIHDCFIERVEWDITYPYISHEKRLNSCCRAVERNVVRAALLAGRFE 6326
Query 6230 VLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNC 6289
++DIGNPK I V V+W +YDAQP S K+++LFY+ + F+DG+CLFWNC
Sbjct 6327 RVYDIGNPKGIPIVDDPVVDWHYYDAQPLSK---KVQQLFYTEDCAKN-FSDGLCLFWNC 6382
Query 6290 NVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYY 6349
NV RYP NAIVCRFDTRV S NLPGCDGGSLYVNKHAFHTPA+D SAF +LK LPFFYY
Sbjct 6383 NVPRYPNNAIVCRFDTRVHSEFNLPGCDGGSLYVNKHAFHTPAYDASAFRDLKPLPFFYY 6442
Query 6350 SDSPCESHGK-QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGF 6408
S +PCE HG ++ DIDYVPLKSA CIT CNLGGAVCR HA EYR Y++AYN++ ++GF
Sbjct 6443 STTPCEVHGNGNMLEDIDYVPLKSAVCITACNLGGAVCRKHAAEYRDYMEAYNLVSASGF 6502
Query 6409 SLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGID 6468
LW YK FD YNLW+TFT++Q LEN+AYNV+ +GHF G GE PV+++N+ +YTK D D
Sbjct 6503 RLWCYKTFDVYNLWSTFTKIQGLENIAYNVIKQGHFTGVEGELPVAVVNDKIYTKSDVND 6562
Query 6469 VEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTI 6528
V IFENKTTLP N+AFEL+AKR ++ P+ +L NL VD+ V+WDY+R +TI
Sbjct 6563 VCIFENKTTLPTNIAFELYAKRAVRSHPDFNLLRNLEVDVCYKFVLWDYERSNIYGSATI 6622
Query 6529 GVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQ 6588
GVC TDI S+L + FD R G ++ F + NG+LI++ VK
Sbjct 6623 GVCKYTDI------DVNSALNICFDIRDNGSLERFMSLPNGILISDRKVKNYPCIVSSNY 6676
Query 6589 ASVNGVTLIGESVKTQ-----------FNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQ 6637
A NG + + +Q F +KKV+ Q +TY+T R + DF P S+
Sbjct 6677 AYFNGTLIRDNTGNSQSSDGEVKQPVTFYIYKKVNNEFVQFTDTYYTLGRTVSDFTPVSE 6736
Query 6638 METDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDF 6697
ME DFL L D FI++YKLE YAFEH+VYGDFS LGGLHL+IGL K+ Q+ + +E+
Sbjct 6737 MEKDFLALDSDVFIKKYKLEAYAFEHVVYGDFSRTTLGGLHLLIGLYKKHQEGHIIMEEM 6796
Query 6698 IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEIS 6757
+ +TV NYF+T++ T S K VCSVIDL LDDFV+IIK+ DLSV+SKVVK+ ID I
Sbjct 6797 LKERATVHNYFVTESNTASFKAVCSVIDLKLDDFVDIIKAMDLSVVSKVVKIPIDLTMIE 6856
Query 6758 FMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMM 6817
FMLWCKDG V+TFYP+LQA W+PG+AMP+L+K+Q LE C L NY ++ +P+G+ M
Sbjct 6857 FMLWCKDGQVQTFYPRLQAINDWKPGLAMPSLFKVQNSNLEPCMLPNYKQSIPMPQGVHM 6916
Query 6818 NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND 6877
N+AKY QLCQYLNT T+AVP NMRV+HFGAGSDKGVAPG++VLRQWLPT +L+D+DLN+
Sbjct 6917 NIAKYMQLCQYLNTCTIAVPANMRVMHFGAGSDKGVAPGSSVLRQWLPTDAILIDNDLNE 6976
Query 6878 FVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLA 6937
+VSDAD TL GDC TV + DL+ISDMYDP TK V + N++K FF YLC FIK LA
Sbjct 6977 YVSDADITLFGDCVTVRVGQQVDLLISDMYDPSTKVVGETNEAKALFFVYLCNFIKNNLA 7036
Query 6938 LGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGY 6997
LGGS+A+KITEHSW+A+LY+LMG F+WWT F TN NASSSE FLIG NYLG+ KE IDG
Sbjct 7037 LGGSVAIKITEHSWSAELYELMGRFAWWTVFCTNANASSSEGFLIGINYLGELKEVIDGN 7096
Query 6998 TMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLII 7057
MHANYIFWRNT + LS+YSLFD+S+FPLKL+GT V+ LKE+QIN+++ SLL +G+LII
Sbjct 7097 VMHANYIFWRNTTLMNLSTYSLFDLSRFPLKLKGTPVLQLKESQINELVISLLSQGKLII 7156
Query 7058 RENNRVVVSSDILVN 7072
R+N+ + VS+D+LVN
Sbjct 7157 RDNDTLSVSTDVLVN 7171
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 6106 bits (15841), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3039/5799 (52%), Positives = 3954/5799 (68%), Gaps = 180/5799 (3%)
Query 1343 ILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDY-GVRFFFY 1401
++ VS + M+ +E L+P+ +D A + ++R +EG+ G F+ Y
Sbjct 1216 LVDVVSMSFSAMVNFGKEKGLLIPVVIDYPAFLKVLKR----FSPKEGLFSSNGYEFYGY 1271
Query 1402 TSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTT 1461
+ +P+ + LNSL PL+ +P G++ +G L +A MR L P V V S +V
Sbjct 1272 SRDKPLHEVSKDLNSLGRPLIMIPFGFIVNGQTLAVSAVSMRGLTVPHTVVVPSESSVPL 1331
Query 1462 YNGYLT---SSSKTSEEHFVETVSLAGSYRDWSYSGQRTELGVE------FLKRGDKIVY 1512
Y Y S T+ + FV + L G+ RDW +T V+ KRG+ Y
Sbjct 1332 YRAYFNGVFSGDTTAVQDFVVDILLNGA-RDWDV--LQTTCTVDRKVYKTICKRGN--TY 1386
Query 1513 HTLESPVEFHLDGEVL----SLDKLKSLLSLREVKT---IKVFTTVDNTNLHTQLVDMSM 1565
+ + + G+V+ ++ K ++ L + IKV TTVD N T LV +
Sbjct 1387 LCFDDTNLYAITGDVVLKFATVSKARAYLETKLCAPEPLIKVLTTVDGINYSTVLVSTAQ 1446
Query 1566 TYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAF-EYYHTLDESFLGRYM 1624
+Y Q G + DG D + P EG + + + A EYY D + + R M
Sbjct 1447 SYRAQIGTVFCDGHDWSNKNPMPTDEGTHLYKQDNFSSAEVTAIREYYGVDDSNIIARAM 1506
Query 1625 SALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDA 1684
S + W + V G + D+NCYL+ + LQ ++V F+ P + AY + G+
Sbjct 1507 SIRKTVQTWPYTVVDGRVLLAQRDSNCYLNVAISLLQDIDVSFSTPWVCRAYDALKGGNP 1566
Query 1685 ANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEA 1744
+++A T G D ++ +L H + +A+RV+ VC+HCG TG +A
Sbjct 1567 LPMAEVLIALGKATPGVSDDAHMVLSAVLNHGTV-TARRVMQTVCEHCGVSQMVFTGTDA 1625
Query 1745 VMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQ-QGTFLCANE 1803
+ G++ D+L VS+ C CGR A +Y+ +Q+S +++MS P + L G + A
Sbjct 1626 CTFYGSVVLDDLYAPVSVVCQCGRPAIRYVSEQKSPWLLMSCTPTQVPLDTSGIWKTAIV 1685
Query 1804 YTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDG 1863
+ G GHY + + D + S+ K P TD+ Y TS+T+ K +Y LDG
Sbjct 1686 FRGPVTAGHYMYAVNGTLISVYDANTRRRTSDLKLPATDILYGPTSFTSDSKVETYYLDG 1745
Query 1864 VTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLT-CSNTKFADDLNQMT 1922
V T I+P Y K+ + Y+T PI++V P S+D F L+ C N + A+ N+
Sbjct 1746 VKRTTIDPDFSKYVKRGDYYFTTAPIEVV-AAPKLVTSYDGFYLSSCQNPQLAESFNKAI 1804
Query 1923 GFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKP 1982
TK +L +T +P++ GDVVAI + A G+ + KP+++ +P
Sbjct 1805 NATKTGPMKL-LTMYPNVAGDVVAISDDNVVAH-PYGSLHMGKPVLF---------VTRP 1853
Query 1983 NTWC-LRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIEC 2041
NTW L L ST V+T N+++VLAV+ P + E E P K I
Sbjct 1854 NTWKKLVPLLSTVVVNTPNTYDVLAVDPL------------PVNNETSEEPISVKAPIPL 1901
Query 2042 -DVKTTEVVGNVILKPSDEG-VKVTQELGHEDLMAAYVENTS-ITIKKPNELSLALGLKT 2098
+K T V+ P ++G + +E DL YVE + K + LS LGL+
Sbjct 1902 YGLKATMVLNGTTYVPGNKGHLLCLKEFTLTDLQTFYVEGVQPFVLLKASHLSKVLGLRV 1961
Query 2099 IATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTL-LFQLC 2157
+ +N + + AY A RL RV + + + T + +
Sbjct 1962 --SDSSLHVNHLSKGVVYAYA--------------ATRLTTRVTTSLLGGLVTRSVRKTA 2005
Query 2158 TFTKSTNS------------RIRASLPTTIAKNSVKSVAKL-CLDAG-------INYVKS 2197
F +STN ++ + K + V+ + + G +NY++S
Sbjct 2006 DFVRSTNPGSKCVGLLCLFYQLFMRFWLLVKKPPIVKVSGIIAYNTGCGVTTCVLNYLRS 2065
Query 2198 -------PKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELY--L 2248
+ KL +++ + CL IC GV LS APS + +
Sbjct 2066 RCGNISWSRLLKLLRYMLYIWFVWTCL--TIC-----GVWLSEPYAPSLVTRFKYFLGIV 2118
Query 2249 NSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAY 2308
+ ++ + +C++G+DSLD YPAL Q S + T + + E AY
Sbjct 2119 MPCDYVLVNETGTGWLHHLCMAGMDSLD-YPALRMQQHRYGS-PYNYTYILMLLEAFFAY 2176
Query 2309 MLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFY 2368
+L+T ++G+ A++ + Y + NSWL+ F+ I+++ P ++M+RMYI A +
Sbjct 2177 LLYTPALPIVGILAVLHLIVLYLPIP-LGNSWLVVFLYYIIRLVPFTSMLRMYIVIAFLW 2235
Query 2369 YIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWN 2428
+K ++H+ GC + C+MCYK+N A R+EC+T+VNG+KR FYV ANGG FC HNWN
Sbjct 2236 LCYKGFLHVRYGCNNVACLMCYKKNVAKRIECSTVVNGVKRMFYVNANGGTHFCTKHNWN 2295
Query 2429 CLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQK 2488
C++CDT+ STFI +VA DLS QFKRPI TD++ Y V SV V+NG ++ YF+ GQ+
Sbjct 2296 CVSCDTYTVDSTFICRQVALDLSAQFKRPIIHTDEAYYEVTSVEVRNGYVYCYFESDGQR 2355
Query 2489 TYERHPLSHFVNLDNLRANNTKGSLP-INVIVFDGKSKCDESASKSASVYYSQLMCQPIL 2547
+YER P+ F N+ L + KG+ P NV+VFD ++ +E+A K+A++YY+QL C+PIL
Sbjct 2356 SYERFPMDAFTNVSKLHYSELKGAAPAFNVLVFDATNRIEENAVKTAAIYYAQLACKPIL 2415
Query 2548 LLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVL 2607
L+D+ +V VGD ++ MF+AY + +S+ M+K+K L +TA +++ G+ ++ VL
Sbjct 2416 LVDKRMVGVVGDDATIARAMFEAYAQNYLLKYSIAMDKVKHLYSTALQQISSGMTVESVL 2475
Query 2608 STFVSAARQGVVD--TDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDL 2665
FV + R D +DVDT D++ C++L H E T DS NN + TY K + ++ ++
Sbjct 2476 KVFVGSTRAEAKDLESDVDTNDLVSCIRLCHQEGWEWTTDSWNNLVPTYIKQDTLSTLEV 2535
Query 2666 GACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTR 2725
G + NA+++NA +AK V+LIW D++ LSE +R+Q++ AA+K + +T ++ +
Sbjct 2536 GQFMTANAKYVNANIAKGAAVNLIWRYADFIKLSESMRRQLKVAARKTGLNLLVTTSSLK 2595
Query 2726 QVVNVITTKISLKGG--KIVSTCFKLMLKATLLCVLAA---LVCYIVMPVHTLSIHDGYT 2780
V + T + GG +IVS L+ LL VL YI+ P+
Sbjct 2596 ADVPCMVTPFKIIGGHRRIVSWRRVLIHVFMLLVVLNPQWFTPWYIMRPIEY-------- 2647
Query 2781 NEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIG 2840
++ +K I + V RDI S D CFANK + F+ W+S R GSY N + CP+V +++ +G
Sbjct 2648 -NVVDFKVIDNAVIRDITSADQCFANKFSAFENWYSNRYGSYVNSRGCPMVVGVVSDIVG 2706
Query 2841 FIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFK 2900
+VPGLP LR + L + AVG++CYTP I Y F TSACVLAA CT+F
Sbjct 2707 SLVPGLPARFLR-VGTTLLPLVNYGLGAVGSVCYTPHYAINYDVFDTSACVLAATCTLFS 2765
Query 2901 DAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAE 2959
A G+ +PYC D L++ + Y L+P Y + S I+FP + V +V T E
Sbjct 2766 SASGERMPYCADAALIQNASRYDMLKPHVMYPFYEHSGYIRFPEV-ISAGVHIVRTMAME 2824
Query 2960 YCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALD 3019
YC+ G C+ SE G+C+S RWV+NN ++R SGV+CG A +L N+ P+ PVGA+D
Sbjct 2825 YCKVGRCDVSEAGLCMSLQPRWVVNNAYFRQQSGVYCGTSAFDLFMNMLLPIFTPVGAVD 2884
Query 3020 VSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLP 3079
++ S++ G ++A++V+ + YY ++FRR FG+Y+ V+ N L F+++ +LCL Y LP
Sbjct 2885 ITTSILMGALLAVVVSMSLYYLLRFRRAFGDYSGVIFTNILAFVLNVIVLCLEGPYPMLP 2944
Query 3080 GVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLR 3139
+Y++ +LY T YF +D++ + H+ + MF+ +VP W+T +Y+ + +H WF + +
Sbjct 2945 SIYAMVFLYATCYFGSDIACMMHVSFLIMFAGVVPLWVTVLYIVVVLSRHILWFASLCTK 3004
Query 3140 KRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALD 3199
+ V + F +F++AAL TF+L+KE++L+L+ E + Y +YLA+YNKYKY+SG +D
Sbjct 3005 RTVQVGDLAFHSFQDAALQTFMLDKEVFLRLKRE--ISSDAYFKYLAMYNKYKYYSGPMD 3062
Query 3200 TTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQ 3259
T +YREAAC HL AL +SN G D +YQPP+ S+ SA LQ+G +MA PSG VE C+V+
Sbjct 3063 TAAYREAACSHLVMALEKYSNGGGDTIYQPPRCSVASAALQAGLTRMAHPSGLVEPCLVK 3122
Query 3260 VTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIG 3319
V G+ TLNG+WLD+ V CPRHV+C+ +++ NP+Y L +R +N+ F V +RVIG
Sbjct 3123 VNYGSMTLNGIWLDNFVICPRHVMCSRDELANPDYPRLSMRAANYDFHVSQNGHNIRVIG 3182
Query 3320 HSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGS 3379
H+M+ LL+L VD +NPKTP Y F+R+ GQ S+LACY+G P+GVY C +R N T++ S
Sbjct 3183 HTMEGSLLKLTVDVNNPKTPAYSFIRVSTGQAMSLLACYDGLPTGVYTCTLRSNGTMRAS 3242
Query 3380 FLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTT 3439
FL GSCGS GF ++ V FCY+H +ELP G H GTD G FYGPF D+Q Q A D T
Sbjct 3243 FLCGSCGSPGFVMNGKEVQFCYLHQLELPNGTHTGTDFSGVFYGPFEDKQVPQLAAPDCT 3302
Query 3440 ITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGI 3499
IT+NVLAWLYAAV++G+ WFL + + + +FN A+KY + +T + + +L PL+A+TGI
Sbjct 3303 ITVNVLAWLYAAVLSGENWFLTKSSISPAEFNNCAVKYMCQSVTSESLQVLQPLAAKTGI 3362
Query 3500 AVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHW 3559
+V M +ALK LL G GRTI+GS LEDE TP+D+ RQ GV QGKF+ + + T W
Sbjct 3363 SVERMLSALKVLLSAGFCGRTIMGSCSLEDEHTPYDIGRQMLGVKLQGKFQSMFRWTLQW 3422
Query 3560 MLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAM------LLVKHKHAFL 3613
+ F+ ++LIL+Q QW+ LPFTL + I A+ LL+KHKH +L
Sbjct 3423 FAIIFVLTILILLQLAQWTFV------GALPFTLLLPLIGFVAVCVGFVSLLIKHKHTYL 3476
Query 3614 CLFLLPSLATVAYFNMVYMP---ASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLI 3670
++LLP AY+N Y P +++ + ++ + G L ++ + A LL
Sbjct 3477 TVYLLPVAMVTAYYNFQYTPEGVQGYLLSLYNYVNPGRIDVIGTDLLTMLIISVACTLL- 3535
Query 3671 LMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMF 3730
+ R V DA R+W + + +Y + G+A AIS ++SV +NY+GV ++
Sbjct 3536 --SVRMVRTDAYSRIWYVCTAVGWLYNCWTGSADTVAISYLTFMVSVFTNYTGVACASLY 3593
Query 3731 LARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDY 3790
A+ +V+V P + + +C+++ Y +GY C CYFG+F L+NR FR TLG Y+Y
Sbjct 3594 AAQFMVWVLKFLDPTILLLYGRFRCVLVCYLLVGYLCTCYFGVFNLINRLFRCTLGNYEY 3653
Query 3791 LVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLL 3850
+VS+QE RYMNS GLLPP +S A LNIKL GIGG P +V+T+QS M+D+KCTSVVLL
Sbjct 3654 VVSSQELRYMNSHGLLPPTNSWQALMLNIKLAGIGGIPIYRVSTIQSNMTDLKCTSVVLL 3713
Query 3851 SVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEE 3910
SVLQQLRVESSSKLWA CV+LHN+IL + TEAFE VSLLSVLLS+ GA++++ LC
Sbjct 3714 SVLQQLRVESSSKLWALCVKLHNEILASNSPTEAFEAFVSLLSVLLSLPGAINLDELCSS 3773
Query 3911 MLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR 3970
+L+N + LQA+ASEFS+L SY Y AQ+AY+ AVA G + LKK++NVAKS D+
Sbjct 3774 ILENNSVLQAVASEFSNLSSYVDYENAQKAYDTAVATGAPASTVNALKKAMNVAKSVLDK 3833
Query 3971 DAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNAR 4030
D A RKLE+M++ AMT MYKQAR+ED+R+KVT+AMQTMLF M+R+LD+DAL+NI+NNAR
Sbjct 3834 DVATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNAR 3893
Query 4031 DGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSE 4090
+G VPL +IP T A KL++VVPD+ Y T T TYA + W++ QV DAD K V ++
Sbjct 3894 NGVVPLGVIPRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGKTVNATD 3953
Query 4091 INMDNSPNLAWPLIVTALR--ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAY 4148
I +NS NLAWPL+VTA R A S VKLQNNEL P +++M+ AG +QTAC D A+AY
Sbjct 3954 ITRENSVNLAWPLVVTAQRQQATSPVKLQNNELMPQTVKRMNVVAGVSQTACVTD-AVAY 4012
Query 4149 YNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFI 4208
YN +K GR V+A+L+D L +A+ KS G G + ELEPPC+F+ DTPKGP +KYLYF
Sbjct 4013 YNATKEGRHVMAILADTDGLAFAKVEKSTGDGFVILELEPPCKFMVDTPKGPALKYLYFT 4072
Query 4209 KGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPI 4268
KGL NL RG VLG+LA TVRL AG+ATEV +NS++LS C+F+VDP YKDYL +GG PI
Sbjct 4073 KGLKNLCRGTVLGTLACTVRLHAGSATEVASNSSILSLCSFSVDPEATYKDYLDNGGSPI 4132
Query 4269 TNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQ 4328
NCVKML HTGTG AIT P+AN+DQESFGGASCCLYCRCHI+HP G C KGK+VQ
Sbjct 4133 GNCVKMLTPHTGTGLAITAKPDANIDQESFGGASCCLYCRCHIEHPGASGVCKYKGKFVQ 4192
Query 4329 IPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSA-AR 4387
IP NDP+GF +RN VC VC MW+GYGC C LRE +Q+ D FLNRV G S AR
Sbjct 4193 IPLVGVNDPIGFCIRNVVCAVCNMWQGYGCPCSSLREINLQARD-ECFLNRVRGTSGVAR 4251
Query 4388 LTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMS 4447
L P G+G D+V RAFDI N KVAGF LK NCCR+QE D +G LDSYFVVKRHT S
Sbjct 4252 LVPLGSGVQPDIVLRAFDICNTKVAGFGLHLKNNCCRYQELDADGTQLDSYFVVKRHTES 4311
Query 4448 NYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGN 4507
NY E+ Y +KDC VA HDFFKF ++G M PH+SR+RLTKYTMADLVY+LRHFD N
Sbjct 4312 NYLLEQRCYEKLKDCGVVARHDFFKFNIEGVMTPHVSRERLTKYTMADLVYSLRHFDNNN 4371
Query 4508 CDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRD 4567
CDTLKEILV CC DYF++KDWYD VENPDI+RVY NLGE VR+++L V+ D+M +
Sbjct 4372 CDTLKEILVLRGCCTADYFDRKDWYDPVENPDIIRVYHNLGETVRKAVLSAVKMADSMVE 4431
Query 4568 AGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMD 4627
G++GVLTLDNQDLNG WYDFGDF++ G GV ++D+YYSL MP+ T+T LAAE H+D
Sbjct 4432 QGLIGVLTLDNQDLNGQWYDFGDFIEGPAGAGVAVMDTYYSLAMPVYTMTNMLAAECHVD 4491
Query 4628 ADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFS 4687
D +KP WD+ KYD+T+ + LF +YFKYWD YHPNC+ C DDRCILHCANFN+LFS
Sbjct 4492 GDFSKPKRVWDICKYDYTQFKYSLFSKYFKYWDMQYHPNCVACADDRCILHCANFNILFS 4551
Query 4688 TVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADP 4747
V P TSFGPLV+KI+VDGVPFVVSTGYH+RELGVV NQD+ H+ RLS +ELLVYAADP
Sbjct 4552 MVLPNTSFGPLVQKIYVDGVPFVVSTGYHYRELGVVMNQDIRQHAQRLSLRELLVYAADP 4611
Query 4748 AMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELK 4807
AMH A+ N L DKRT C SVAA+T V FQTVKPG FN+DFY+FAV GFFKEGS++ K
Sbjct 4612 AMHVAASNALADKRTVCMSVAAMTTGVTFQTVKPGQFNEDFYNFAVKCGFFKEGSTISFK 4671
Query 4808 HFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNL 4867
HFF+AQDGNAAISDYDYYRYNLPTMCDI+QLLF +EVVDKYFDCYDGGC+ A+QV+V N
Sbjct 4672 HFFYAQDGNAAISDYDYYRYNLPTMCDIKQLLFSLEVVDKYFDCYDGGCLQASQVVVANY 4731
Query 4868 DKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVA 4927
DKSAGFPFNK+GKARLYY+S+SY DQD LFAYTKRNV+PTITQMNLKYAISAKNRARTVA
Sbjct 4732 DKSAGFPFNKFGKARLYYESLSYADQDELFAYTKRNVLPTITQMNLKYAISAKNRARTVA 4791
Query 4928 GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWD 4987
GVSI STMTNRQFHQK+LKSIAA RGA+VVIGT+KFYGGW+ ML+T+ VE PHLMGWD
Sbjct 4792 GVSIASTMTNRQFHQKMLKSIAAARGASVVIGTTKFYGGWNRMLRTLCEGVENPHLMGWD 4851
Query 4988 YPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPG 5047
YPKCDRAMPN+LRI ASL+LARKH TCCN S RFYRLANECAQVLSEMV+CGG YVKPG
Sbjct 4852 YPKCDRAMPNLLRIFASLILARKHATCCNASERFYRLANECAQVLSEMVLCGGGFYVKPG 4911
Query 5048 GTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD 5107
GTSSGD+TTAYANSVFNICQAV+AN+N LS DGNKI YV+ LQ RLY +YR+ VD
Sbjct 4912 GTSSGDSTTAYANSVFNICQAVSANLNTFLSIDGNKIYTTYVQELQRRLYLGIYRSNTVD 4971
Query 5108 HEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAK 5167
+E V ++Y YLRKHFSMMILSDD VVCYN++YA +G VA I+ FK +LY+QNNVFMSE+K
Sbjct 4972 NELVLDYYNYLRKHFSMMILSDDGVVCYNADYAQKGYVADIQGFKELLYFQNNVFMSESK 5031
Query 5168 CWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIER 5227
CW E D+TKGPHEFCSQHTMLV + VYLPYPDPSRILGAGCFVDD++KTDGTLM+ER
Sbjct 5032 CWVEPDITKGPHEFCSQHTMLVDMKGEQVYLPYPDPSRILGAGCFVDDLLKTDGTLMMER 5091
Query 5228 FVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEP 5287
+VSLAIDAYPLTKHP+ EY +VF YLQYI+KLH+ELTGH+LD YSVML +DN S+YWE
Sbjct 5092 YVSLAIDAYPLTKHPDPEYQNVFWCYLQYIKKLHEELTGHLLDTYSVMLASDNASKYWEV 5151
Query 5288 EFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVN 5347
EFYE MY LQ+VG CV+CNSQTSLRCG CIRRPFLCCKCCYDHV+ST+HKLVLSV
Sbjct 5152 EFYENMYMESATLQSVGTCVVCNSQTSLRCGGCIRRPFLCCKCCYDHVVSTTHKLVLSVT 5211
Query 5348 PYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDF 5407
PYVCN P CDV DVTQLYLGGMSYYC+ H+PPISFPLCANGQVFGLYKN C GS +V DF
Sbjct 5212 PYVCNNPSCDVADVTQLYLGGMSYYCRDHRPPISFPLCANGQVFGLYKNICTGSPDVADF 5271
Query 5408 NAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLS 5467
N++ATCDW+N+ DY+LANT TERLKLFAAETL+ATEE K +Y A V+EVLSDREL LS
Sbjct 5272 NSLATCDWSNSKDYVLANTATERLKLFAAETLRATEENAKQAYASAVVKEVLSDRELVLS 5331
Query 5468 WEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFV 5527
WE GK RPPLNRNYVFTG+ +TKNSKVQ+GEY FEKGDYGD V YR +TTYKL VGDYFV
Sbjct 5332 WETGKTRPPLNRNYVFTGFHITKNSKVQLGEYIFEKGDYGDVVNYRSSTTYKLQVGDYFV 5391
Query 5528 LTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGT 5587
LTSH+V PLS+PTL+PQE Y ++ GLYP +N+ + F+SNV +YQ+VGM +Y+T+QGPPGT
Sbjct 5392 LTSHSVQPLSSPTLLPQERYTKLVGLYPAMNVPESFASNVVHYQRVGMSRYTTVQGPPGT 5451
Query 5588 GKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKF 5647
GKSH +IGLALYYPSA+IVYTACSHAAVDALCEKA K LPI++CSRI+PA+ARVECF KF
Sbjct 5452 GKSHLSIGLALYYPSAKIVYTACSHAAVDALCEKAHKNLPINRCSRIVPAKARVECFSKF 5511
Query 5648 KVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLP 5707
KVN QYVF T+NALPETTADI+V DE+SM TNYDLS++NAR+RAKH VY+GDPAQLP
Sbjct 5512 KVNDVGAQYVFSTINALPETTADILVVDEVSMCTNYDLSMINARVRAKHIVYVGDPAQLP 5571
Query 5708 APRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD 5767
APRTLLTKGTL PE+FNSVCRLM +GPD+FL TC RCP EIVDTVSALVYD KLKA+K
Sbjct 5572 APRTLLTKGTLAPEHFNSVCRLMVAVGPDIFLATCYRCPKEIVDTVSALVYDKKLKANKV 5631
Query 5768 KSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL 5827
+ +C+K +YKG +THD SSAIN+PQ+G+V+EFL +NP W+ AVFISPYNSQN+VA ++L
Sbjct 5632 TTGECYKCYYKGSVTHDSSSAINKPQLGLVKEFLIKNPKWQSAVFISPYNSQNSVARRML 5691
Query 5828 GLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQ 5887
GL TQTVDSSQGSE+DYVI+ QT++TAH+ NVNRFNVAITRAK GILC+MSD LY+ L+
Sbjct 5692 GLQTQTVDSSQGSEFDYVIYCQTSDTAHALNVNRFNVAITRAKKGILCVMSDSTLYESLE 5751
Query 5888 FTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFK-TEGLCVDIPG 5946
FT L++ +Q+E GLFKDC+K L P APT +SV+ KFK E LCV
Sbjct 5752 FTPLDVNDYVKPKMQSEVTVGLFKDCAK-AEPLGPAYAPTFVSVNDKFKLNESLCVHFDT 5810
Query 5947 IPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTN 6006
M Y RLIS MGFK + + GY +FITRE+AIR VR W+GFDVEG HA +GTN
Sbjct 5811 TELQMPYNRLISKMGFKFDLNIPGYSKLFITREQAIREVRGWVGFDVEGAHACGPNIGTN 5870
Query 6007 LPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRI 6066
LPLQ+GFSTGVN V P+GY+DTE+ + V +K PPGDQFKHLIPLM KG PW+VVR
Sbjct 5871 LPLQIGFSTGVNFVVTPSGYIDTESGSRLANVVSKAPPGDQFKHLIPLMRKGEPWSVVRK 5930
Query 6067 KIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTY 6126
+IV+ML DTL G+SD V FV WAHGFELT++ YF K+GPER C +C +RAT FS+ Y
Sbjct 5931 RIVEMLCDTLDGVSDTVTFVTWAHGFELTTLHYFAKVGPERKCFMCPRRATLFSSVYGAY 5990
Query 6127 ACWNHSV---GFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLA 6183
+CW+H G D+VYNPF++DVQQWG+ GNLQ NHD C VH AHVASCDAIMTRCLA
Sbjct 5991 SCWSHHRHIGGADFVYNPFLVDVQQWGYVGNLQVNHDNVCDVHKGAHVASCDAIMTRCLA 6050
Query 6184 VHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCV 6243
+H+CF V+W VEYPII +EL +N ACR VQ +V+K+A+ A ++DIGNPKAIK
Sbjct 6051 IHDCFCGEVNWDVEYPIIANELAINRACRSVQRVVLKAAVKALHIETIYDIGNPKAIKVY 6110
Query 6244 PQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRF 6303
W FYD P + +++L Y Y H D+F DG+ +FWNCNVD YP NA+VCRF
Sbjct 6111 GVNVNNWNFYDTNPVVE---GVKQLHYVYDVHRDQFKDGLAMFWNCNVDCYPHNALVCRF 6167
Query 6304 DTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESH---GKQ 6360
DTRVLS LNL GC+GGSLYVN+HAFHT AF+K+AF NLK LPFFYYSD+ CE+
Sbjct 6168 DTRVLSKLNLAGCNGGSLYVNQHAFHTDAFNKNAFVNLKPLPFFYYSDTACENATGVSTN 6227
Query 6361 VVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYN 6420
VS++DYVPLKS CITRCNLGGAVC+ HA+EYR +L++YN M+SAGF+LW+ K FD +N
Sbjct 6228 YVSEVDYVPLKSNVCITRCNLGGAVCKKHADEYRNFLESYNTMVSAGFTLWVDKTFDVFN 6287
Query 6421 LWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPV 6480
LW+TF +LQSLENVAYNV+ GHF AGE PV+I+N+ +Y K DG D +F N T LP
Sbjct 6288 LWSTFVKLQSLENVAYNVLKSGHFTAVAGELPVAILNDRLYIKEDGADKLLFTNNTCLPT 6347
Query 6481 NVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKP 6540
NVAFELWAKR++ VPE+K+L NLGV N VIWDY+ AP +T+G+CT TD+ K
Sbjct 6348 NVAFELWAKRSVNVVPEVKLLRNLGVTCTYNLVIWDYESNAPLVPNTVGICTYTDLTKLD 6407
Query 6541 TESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGES 6600
+ VL DGR F +N + + K + ++GP AS+NGV +
Sbjct 6408 DQ------VVLVDGRQLDAYSKFCQLKNAIYFSPSKPKCVC-TRGPTHASINGVVVEAPD 6460
Query 6601 VKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYA 6660
T F Y + DG Q + YFTQSR ++DF+PR+Q+E DFL+L F+ +Y L
Sbjct 6461 RGTAFWYAMRKDGAFVQPTDGYFTQSRTVDDFQPRTQLEIDFLDLEQSCFLDKYDLHDLG 6520
Query 6661 FEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCV 6720
EHIVYG F G +GGLHL+IG +R + + L +E + D TV +Y + D T SSK V
Sbjct 6521 LEHIVYGQFD-GTIGGLHLLIGAVRRKRTAHLVMETVLGTD-TVTSYAVIDQPTASSKQV 6578
Query 6721 CSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAW 6780
CSV+D++LDDF+ +IK+QD SV+SKVV+ +D+ FMLWCK G + TFYP+LQA Q W
Sbjct 6579 CSVVDIILDDFIALIKAQDRSVVSKVVQCCLDFKVFRFMLWCKGGKISTFYPQLQAKQDW 6638
Query 6781 QPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNM 6840
+PG +MP LYK+Q +LE C L NYG+ A +P G +MNVAKYTQLCQYLNT +LAVP M
Sbjct 6639 KPGYSMPALYKVQNAVLEPCLLHNYGQAARLPSGTLMNVAKYTQLCQYLNTCSLAVPAKM 6698
Query 6841 RVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWD 6900
RV+HFGAGSDKGV PGTAVL+QWLP LVD+DL SDADST +G C T + NKWD
Sbjct 6699 RVMHFGAGSDKGVCPGTAVLKQWLPADAYLVDNDLCYCASDADSTYVGSCETFFSVNKWD 6758
Query 6901 LIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMG 6960
I SDMYD RTK+ + +N SKEGFFTYL GFI+ KLALGGSIA+KITEHSW+ADLY +MG
Sbjct 6759 FIFSDMYDARTKNTSGDNTSKEGFFTYLTGFIRSKLALGGSIAIKITEHSWSADLYAIMG 6818
Query 6961 HFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLF 7020
HF+WWT F T+VN+SSSEAFLIG NY+G +DG+ MHANY+FWRN+ +QLSSYSL+
Sbjct 6819 HFNWWTCFCTSVNSSSSEAFLIGVNYIGV-GALLDGWQMHANYVFWRNSTVMQLSSYSLY 6877
Query 7021 DMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRE 7059
D+ +FPL+L+GT VMSLKE+Q+N+++ +L+ GRLI+R+
Sbjct 6878 DLQRFPLRLKGTPVMSLKEDQLNELVLNLIRAGRLIVRD 6916
Score = 289 bits (739), Expect = 7e-76, Method: Compositional matrix adjust.
Identities = 326/1183 (28%), Positives = 514/1183 (43%), Gaps = 143/1183 (12%)
Query 28 VRGFGDSVEEALSEAREHLKNGTCGLVELEKGV--LPQLEQPYVFIKRSDALSTNHG-HK 84
V G+ +EEAL A++ L+ LV + + P + V I S +TN G
Sbjct 29 VTGWDIPIEEALEYAKQQLRTPEPQLVFVPYYLSHAPGISGDRVVITDSIWYATNFGWQP 88
Query 85 VVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYR-NVLLRKNGNKGAGGHSYGIDLKSY 143
+ EL + DG++YGR G T GVL+P + I ++ +RK G G +S L +
Sbjct 89 IRELAMDKDGVRYGRGG-THGVLLPMQDPSFIMGDIDIQIRK---YGIGANSPPDVLPLW 144
Query 144 DLGDELGTD--PIEDYEQNW---NTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPL 198
D + G D P D+ N K G L+ + DNN G +
Sbjct 145 DGFSDPGPDVGPYLDFPDNCCPTKPKAKRGGDVYLSDQYG-------FDNN-----GILV 192
Query 199 DCIKDFLARAGKSMCTLSEQLDYIESKRGV--YCCRDHEHEIAWFTERSDKSYEHQTPFE 256
+ + L KS TL + L + R Y D ++A R Q+ F
Sbjct 193 EPVMKLLGVI-KSDFTLEQLLAALGKYRTEDGYDLPDGYVKVAIKVGRKAVPVLKQSIFT 251
Query 257 IKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGR-IRSVYPVASPQECNNM 315
+ + P + +P ++ V K G +G+ + +V + S NN
Sbjct 252 VVGVTE-----QLVPGYYYPFSTSSVVEH---TKPTRGGPVGKTVEAV--MLSLYGTNNY 301
Query 316 HLST---LMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYLPTNAVVKMPCPA 372
+ +T +KC++CD W + CG E + ++C + V+K C
Sbjct 302 NPATPVARLKCSYCDYYGWTPLKDIGTVNCLCGAE---FQLTSSCVDAESAGVIKPGCVM 358
Query 373 CQDPEIGPEHSVADYHNHSNIETRLRKGGRTRC-FGGCVFAYVGCYNKRAYWVPRASADI 431
D G RL G RT FGG +++ +G N WVPRA + +
Sbjct 359 LLDKSPG---------------MRLIPGNRTYVSFGGAIWSPIGKVNGVTVWVPRAYSIV 403
Query 432 GSGHTGITGD-NVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSA-FID 489
H+G G + +N++L+E L I + D N A +A+ T A +
Sbjct 404 AGEHSGAVGSGDTVAINKELVEYLIE---GIRVDADTLDNPTCATFIANLDCDTKAPVVH 460
Query 490 TIKSLDYKSFKTIVESCGNYKVTKG-KPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIF 548
T++SL C K+ G KP+ + + L + Q A ++
Sbjct 461 TVESLQ--------GLCLANKIMLGDKPLP----TDEFHPFIVGL-AYHVQRACWYGALA 507
Query 549 ARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY-VTGGLVQ 607
+RT +A D R + ++ VY + + AY V +
Sbjct 508 SRTFEA----FRDFVRTEEERFAQFFGKVCAPINGCVYLAYTTGRVTLFSAYQVLNTAIA 563
Query 608 QTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAW----EILKFLITGVFDIVKGQ 663
++ + V+ L+PI EW+ K+S K AW E L L F +VKG+
Sbjct 564 KSKDAFGGVAAIVVDMLKPILEWVLKKMSIA----KGAWLPYAEGLLALFKAQFTVVKGK 619
Query 664 IQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQCIRG 723
Q ++ D++ + + V AG K+ +L G + KG+ +
Sbjct 620 FQFLRASLNSKCHSLCDLLTTIMSKLLTSVKWAGCKVDALYTGTYYYFSRKGVLTEVQLC 679
Query 724 KEQLQLLM-PLKAPKEVTFLEGDSHDTV-LTSEEVVLKNGELEALETPVDSFTNGAIVGT 781
++L LL+ P + EV L+GD V LT E+ G LE + D + GT
Sbjct 680 AKRLGLLLTPKQQKMEVEVLDGDFDAPVTLTDLELEECTGVLEEVFGASDV---KLVKGT 736
Query 782 PVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVR 841
V + + + +D Y + G + FRL+GG + VTFG++ V + V
Sbjct 737 LVSLASKLFVRTEDGFLYRYVKSGGV-LGKAFRLRGGG-VSKVTFGDEEVHTIPNTVTVN 794
Query 842 ITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTN-----MGI 896
++++ E +D +L++ + + VE GT++ + ACVV +AV + L SDL ++ I
Sbjct 795 FSYDVCEGLDAILDKVMAPFQVEEGTKLEDLACVVQKAVYERL---SDLFSDCPAELRPI 851
Query 897 DLDEWSVATFYLFDDAGEENFSSRMYCSF---YPPDEEEEDDAECEEEEIDETCEHEYGT 953
+L+++ + +++ E+ MY S P D+E DD I++T E +
Sbjct 852 NLEDFLTSECFVYSKDYEKILMPEMYFSLEDAVPVDDEMVDD-------IEDTVEQASDS 904
Query 954 EDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLT 1013
+D + G +E ED D+T + ++ TP GY K+
Sbjct 905 DDQWLG---------------DEGAED-CDNTIQDVDVATS-MTTP-------CGYTKIA 940
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNG 1073
++V IKC DIV+EA++ + V+VNAAN++L HGGGVAGALN+ATN AMQKES +YIK NG
Sbjct 941 EHVYIKCADIVQEARNYSYAVLVNAANVNLHHGGGVAGALNRATNNAMQKESSEYIKANG 1000
Query 1074 PLTVGGSCLLSGHNLAKK-CLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIF 1132
L GG LLS H LA LHVVGP+ G+D+ LL A Y + D +L PL+SAGIF
Sbjct 1001 SLQPGGHVLLSSHGLASHGILHVVGPDKRLGQDLALLDAVYAAYTGFDSVLTPLVSAGIF 1060
Query 1133 GAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPR 1175
G +SL V+ V Y+ V D+ LYE+ + D P+
Sbjct 1061 GFTVEESLCSLVKNVACTTYVVVYDRQLYERALATSFDVPGPQ 1103
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 5980 bits (15515), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 3064/6175 (50%), Positives = 4080/6175 (66%), Gaps = 262/6175 (4%)
Query 1090 KKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
++C V +L GE + + + E + + +A + A PL + ++V+
Sbjct 968 EECSEVEASDLEEGESECISETSTEQVDVSHEISDDEWAAAVDEAFPLDEAEDVTESVQE 1027
Query 1150 Q---VYIAVNDKALYEQVVMDYLDN---LKPRVEAPKQ----------------EEPPNT 1187
+ V + V D A + V+ D L + VE P Q E P
Sbjct 1028 EAQPVEVPVEDIA--QVVIADTLQETPVVSDTVEVPPQVVKLPSEPQTIQPEVKEVAPVY 1085
Query 1188 EDSKTEEKSVVQKPVDVKPK-------------IKACIDEVT-TTLEETKFLTNKLLLFA 1233
E + +SV KP ++ K I C+ V ++ K +L+ A
Sbjct 1086 EADTEQTQSVTVKPKRLRKKRNVDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNA 1145
Query 1234 ---------DINGKLYHDSQNMLRGEDMSFLEKDAPYMVGD-VITSG-----DITCVVIP 1278
I G + S+ ++ E ++ P VGD V+ G +I VV P
Sbjct 1146 ANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGP 1205
Query 1279 SKKAGGTTEMLSRALKKVPVDEYITT-YPGQGCAG--------YTLEEAKTALKKCKSAF 1329
+A +LS+ K + + T G G Y + EAKT + ++
Sbjct 1206 DARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQ 1265
Query 1330 YVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQE 1389
V S + L LR + A++ + +C D A ++ K +
Sbjct 1266 DVYKSLTIVDIPQSLTFSYDGLRGAIRKAKDYGFTVFVCTDNSANTKVLRNKGVDYTKKF 1325
Query 1390 GIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPA 1449
VD GV+++ YTSK+ + I+ + N + +++MP+GYV+HG +L +A +R + P
Sbjct 1326 LTVD-GVQYYCYTSKDTLDDILQQANK-SVGIISMPLGYVSHGLDLIQAGSVVRRVNVPY 1383
Query 1450 VVSVSSPDAVTTYNGYLTSSSKTS-EEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGD 1508
V +++ + ++ K + E F++ V G Y W EL V+ L+
Sbjct 1384 VCLLANKEQEAIL---MSEDVKLNPSEDFIKHVRTNGGYNSWHLV--EGELLVQDLRLNK 1438
Query 1509 KI------------VYHTLESPVEFHLDGEVLSLDKLKSLLSLREVK--TIKVFTTVDNT 1554
+ V++ +++ F + +L ++ L R + TI+V TVD
Sbjct 1439 LLHWSDQTICYKDSVFYVVKNSTAFPFE----TLSACRAYLDSRTTQQLTIEVLVTVDGV 1494
Query 1555 NLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFV---LPSDDTLRSEAFEY 1611
N T +++ TY Q G + +GAD++ P G + ++ L +D+T + E
Sbjct 1495 NFRTVVLNNKNTYRSQLGCVFFNGADISDTIPDEKQNGHSLYLADNLTADETKALK--EL 1552
Query 1612 YHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQL-EVKFNAP 1670
Y +D +FL R+ S KWK + S+K +DNNCYL++V++ L L ++KF P
Sbjct 1553 YGPVDPTFLHRFYSLKAAVHKWKMVVCDKVRSLKLSDNNCYLNAVIMTLDLLKDIKFVIP 1612
Query 1671 ALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE-SAKRVLNVVC 1729
ALQ A+ + + GD+ +F ALI+AY N T G D + +L A L SA+ V C
Sbjct 1613 ALQHAFMKHKGGDSTDFIALIMAYGNCTFGAPDDASRLLHTVLAKAELCCSARMVWREWC 1672
Query 1730 KHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPA 1789
CG K L G++A Y+G + ++L+ ++ C CG + + +V+ + ++++S P
Sbjct 1673 NVCGIKDVVLQGLKACCYVGVQTVEDLRARMTYVCQCGGERHRQIVEHTTPWLLLSGTPN 1732
Query 1790 EYKLQQGT---FLCANEYTG-NYQCGHYTHITAKETL-YRIDGAHLTKMSEYKGPVTDVF 1844
E + T F+ N + G GHY H K L + D ++K S++K VTDV
Sbjct 1733 EKLVTTSTAPDFVAFNVFQGIETAVGHYVHARLKGGLILKFDSGTVSKTSDWKCKVTDVL 1792
Query 1845 YKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYT-EQPIDLVPTQPLPNASFD 1903
+ Y++ V Y LDG TE++P L +Y KD Y+T E P+ P L + +
Sbjct 1793 FPGQKYSSDCNVVRYSLDGNFRTEVDPDLSAFYVKDGKYFTSEPPVTYSPATILAGSVYT 1852
Query 1904 NFKLTCSNTKFADD-----LNQMTGF--TKPASRELSVTFFPDLNGDVVAIDYRHYSASF 1956
N L S+ + D N + GF +KP +++ + +F P +GDV+ ++ Y +
Sbjct 1853 NSCLVSSDGQPGGDAISLSFNNLLGFDSSKPVTKKYTYSFLPKEDGDVLLAEFDTYDPIY 1912
Query 1957 KKGAKLLHKPIVWHINQATTKTTF-KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDN 2015
K GA KPI+W +N+A+ T K N LR ++ P++ N F L+VE T
Sbjct 1913 KNGAMYKGKPILW-VNKASYDTNLNKFNRASLRQIFDVAPIELENKFTPLSVEST----- 1966
Query 2016 LACESQQPTSEEVVENPTIQKE--VIECD-VKTTEVVGNVILKPSDEGVKVTQELGHEDL 2072
P V+ +Q+E +++C + V NV D G V + L EDL
Sbjct 1967 -------PVEPPTVDVVALQQEMTIVKCKGLNKPFVKDNVSFVADDSGTPVVEYLSKEDL 2019
Query 2073 MAAYVE-NTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAI--- 2128
YV+ + + K N LS L L T+ + IN V S L L +A+
Sbjct 2020 HTLYVDPKYQVIVLKDNVLSSMLRLHTVES---GDINVVAASGSLTRKVKLLFRASFYFK 2076
Query 2129 -----------TTSNCAKRLAQRV---------FNNYMPYVFTLLFQLCTFTKSTNSRIR 2168
+C K + + + +++ +F L + +K + ++
Sbjct 2077 EFATRTFTATTAVGSCIKSVVRHLGVTKGILTGCFSFVKMLFMLPLAYFSDSKLGTTEVK 2136
Query 2169 ASLPTT---IAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTA 2225
S T + N VK +D ++ ++ + + + L + L S+ +
Sbjct 2137 VSALKTAGVVTGNVVKQCCTAAVDLSMDKLRRVDWKSTLRLLLMLCTTMVLLSSVYHLYV 2196
Query 2226 AFGVLLSN-------------------FGAPSYCNGVRELY-LNSSNVTTMDFCEG-SFP 2264
VL S+ G S C+G+ Y NS +V T FC S
Sbjct 2197 FNQVLSSDVMFEDAQGLKKFYKEVRAYLGISSACDGLASAYRANSFDVPT--FCANRSAM 2254
Query 2265 CSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIM 2324
C+ CL DS+ YPAL+ +Q +S Y L++ L A E LAYML+T F L L+ +
Sbjct 2255 CNWCLISQDSITHYPALKMVQTHLSHYVLNIDWLWFAFETGLAYMLYTSAFNWLLLAGTL 2314
Query 2325 QVFFGY------FASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIM 2378
FF + S+ + S W I P++ +VRMY A + + K Y H++
Sbjct 2315 HYFFAQTSIFVDWRSYNYAVSSAFWLFTHI----PMAGLVRMYNLLACLWLLRKFYQHVI 2370
Query 2379 DGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTG 2438
+GC + C++CYKRNR TRVE +T+V G KR+FY+ ANGG FC+ HNWNC++CDT G
Sbjct 2371 NGCKDTACLLCYKRNRLTRVEASTVVCGGKRTFYITANGGISFCRRHNWNCVDCDTAGVG 2430
Query 2439 STFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHF 2498
+TFI +EVA DL+ +RPIN TD+S Y VDSV VK + + + GQ YER PL F
Sbjct 2431 NTFICEEVANDLTTALRRPINATDRSHYYVDSVTVKETVVQFNYRRDGQPFYERFPLCAF 2490
Query 2499 VNLDNLR----ANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALV 2554
NLD L+ T G N I++D + ES ++SA VYYSQ++C+ ILL+D +LV
Sbjct 2491 TNLDKLKFKEVCKTTTGIPEYNFIIYDSSDRGQESLARSACVYYSQVLCKSILLVDSSLV 2550
Query 2555 SDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAA 2614
+ VGDS+E++ KMFD++V++F + ++V +KL+ L++TA + +G VL+TF+ AA
Sbjct 2551 TSVGDSSEIATKMFDSFVNSFVSLYNVTRDKLEKLISTARDGVRRGDNFHSVLTTFIDAA 2610
Query 2615 RQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNA 2673
R V++DV+T ++++ ++ +H D+++T +S NN++ +Y K ++++ DLG+ IDCNA
Sbjct 2611 RGPAGVESDVETNEIVDSVQYAHKHDIQITNESYNNYVPSYVKPDSVSTSDLGSLIDCNA 2670
Query 2674 RHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITT 2733
+N V ++ N + IWN YM LS+ L++QIR A +K N+ FRLT + R N+++
Sbjct 2671 ASVNQIVLRNSNGACIWNAAAYMKLSDALKRQIRIACRKCNLAFRLTTSKLRANDNILSV 2730
Query 2734 KISLKGGKIVSTC-----------FKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNE 2782
+ + KIV K + AT++ L A++ Y+ +P ++ + Y +
Sbjct 2731 RFT--ANKIVGGAPTWFNALRDFTLKGYVLATIIVFLCAVLMYLCLPTFSMVPVEFYEDR 2788
Query 2783 IIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQR-GGSYKNDKSCPVVAAIITREIGF 2841
I+ +K + +G+ RD+ D CFANKH F W+ + GG Y N +CP+ A+I G
Sbjct 2789 ILDFKVLDNGIIRDVNPDDKCFANKHRSFTQWYHEHVGGVYDNSITCPLTVAVIAGVAGA 2848
Query 2842 IVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKD 2901
+P +P T L +N + F+ RVF+ G++CYTP I Y F+ S C+L +ECT+F+D
Sbjct 2849 RIPDVP-TTLAWVNNQIIFFVSRVFANTGSVCYTPIDEIPYKSFSDSGCILPSECTMFRD 2907
Query 2902 AMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDAEY 2960
A G+ PYC+D +L G+ +YS++RP RY L DG++ I+FP E ++R+ T +Y
Sbjct 2908 AEGRMTPYCHDPTVLPGAFAYSQMRPHVRYDLYDGNMFIKFPEVVFESTLRITRTLSTQY 2967
Query 2961 CRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDV 3020
CR G+CE ++ G+C++T+G W + N+H+ GV+CG D ++++ + L QP+ +
Sbjct 2968 CRFGSCEYAQEGVCITTNGSWAIFNDHHLNRPGVYCGSDFIDIVRRLAVSLFQPITYFQL 3027
Query 3021 SASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPG 3080
+ S+V G + +T YY K +R F +Y + +++ +C V +
Sbjct 3028 TTSLVLGIGLCAFLTLLFYYINKVKRAFADYTQCAVIAVVAAVLNSLCICFVASIPLCIV 3087
Query 3081 VYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRK 3140
Y+ Y Y TFYFTN+ +F+ H+ W+ MF PIVP W+T +Y + +H W + +K
Sbjct 3088 PYTALYYYATFYFTNEPAFIMHVSWYIMFGPIVPIWMTCVYTVAMCFRHFFWVLAYFSKK 3147
Query 3141 --RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGAL 3198
V +G +F++AA F++NK+ Y LR+ L Y+R+L L+NKYKYFSGA+
Sbjct 3148 HVEVFTDGKLNCSFQDAASNIFVINKDTYAALRNS--LTNDAYSRFLGLFNKYKYFSGAM 3205
Query 3199 DTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMV 3258
+T +YREAA CHLAKAL +S +G+D+LYQPP SITS VLQSG KM+ PSG VE CMV
Sbjct 3206 ETAAYREAAACHLAKALQTYSETGSDLLYQPPNCSITSGVLQSGLVKMSHPSGDVEACMV 3265
Query 3259 QVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQ---AGNVQL 3315
QVTCG+ TLNGLWLD+TV+CPRHV+C A+ + +PNY+ LLI +NHSF VQ L
Sbjct 3266 QVTCGSMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANL 3325
Query 3316 RVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHT 3375
RV+GH+MQ LL+L VD +NP TP Y F ++PG FSVLACYNG P+G + MRPN+T
Sbjct 3326 RVVGHAMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYT 3385
Query 3376 IKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAG 3435
IKGSFL GSCGSVG+ + ++FCYMH MEL G H G+ +G YG F+D+Q Q
Sbjct 3386 IKGSFLCGSCGSVGYTKEGSVINFCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQL 3445
Query 3436 TDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY-EPLTQDHVDILGPLS 3494
TD ++NV+AWLYAA++NG WF+ T++ FN A+ + E + VD+L +
Sbjct 3446 TDKYCSVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALANQFTEFVGTQSVDML---A 3502
Query 3495 AQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVK 3554
+TG+A+ + A+++L G G+ ILGST+LEDEFTP DV Q GV Q +K+
Sbjct 3503 VKTGVAIEQLLYAIQQLY-TGFQGKQILGSTMLEDEFTPEDVNMQIMGVVMQSGVRKVTY 3561
Query 3555 GTHHWMLLTFLTSLLILVQSTQWSLFFFVYEN---AFLPFTLGIMAIAACAMLLVKHKHA 3611
GT HW+ T +++ +I++Q+T+++L+ +++E P MA MLLVKHKH
Sbjct 3562 GTAHWLFATLVSTYVIILQATKFTLWNYLFETIPTQLFPLLFVTMAFV---MLLVKHKHT 3618
Query 3612 FLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLELADTSLSGYRLKDCVMYASALV 3667
FL LFLLP + Y N+VY P +S ++ + WL + + D +Y S +
Sbjct 3619 FLTLFLLPVAICLTYANIVYEPTTPISSALIAVANWLAPTNAYMRTTH-TDIGVYISMSL 3677
Query 3668 LLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTT 3727
+L+++ R + L + + +Y G A I+ V ++TS+Y+ V
Sbjct 3678 VLVIVVKRLYNPSLSNFALALCSGVMWLYTYSIGEA-SSPIAYLVFVTTLTSDYTITVFV 3736
Query 3728 IMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGV 3787
+ LA+ + Y P L + ++ I+L+Y LG+ C CYFG+F LLN R +GV
Sbjct 3737 TVNLAKVCTYAIFAYSPQLTLVFPEVKMILLLYTCLGFMCTCYFGVFSLLNLKLRAPMGV 3796
Query 3788 YDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSV 3847
YD+ VSTQEFR+M + L P++S +A LN KL+GIGG PCIKVA +QSK++D+KCTSV
Sbjct 3797 YDFKVSTQEFRFMTANNLTAPRNSWEAMALNFKLIGIGGTPCIKVAAMQSKLTDLKCTSV 3856
Query 3848 VLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRL 3907
VLLSVLQQL +E++S+ WA CV+ HNDIL A D +EAFEK VSL + L++ G VD++ L
Sbjct 3857 VLLSVLQQLHLEANSRAWAFCVKCHNDILAATDPSEAFEKFVSLFATLMTFSGNVDLDAL 3916
Query 3908 CEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKS 3966
++ D + LQA SEFS L ++A AQ+AY++A+ +GD S VLK L+K++N+AK+
Sbjct 3917 ASDIFDTPSVLQATLSEFSHLATFAELEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKN 3976
Query 3967 EFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNII 4026
+++D A+ RKLE+MADQAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN II
Sbjct 3977 AYEKDKAVARKLERMADQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGII 4036
Query 4027 NNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIV 4086
+NAR+GC+PL++IPL + KL VV+PD+ + + YA ALW+I + + D++IV
Sbjct 4037 SNARNGCIPLSVIPLCASNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIV 4096
Query 4087 QLSEINMDNSPNLAWPLIVTALRAN-SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNA 4145
+ S++ +D++ NL WPL++ RA+ SAVKLQNNE+ P L+ M +AG QT C + ++
Sbjct 4097 KSSDV-VDSNENLTWPLVLECTRASTSAVKLQNNEIKPSGLKTMVVSAGQEQTNC-NTSS 4154
Query 4146 LAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL 4205
LAYY +G + ++ALLSD+ LKWAR DG ++ EL+PPC+F+ PKGP+++YL
Sbjct 4155 LAYYEPVQGRKMLMALLSDNAYLKWARVEGKDGFVSV--ELQPPCKFLIAGPKGPEIRYL 4212
Query 4206 YFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGG 4265
YF+K LNNL+RG VLG +AATVRLQAG+ TE +NS+VLS F VDP KAY D++ +GG
Sbjct 4213 YFVKNLNNLHRGQVLGHIAATVRLQAGSNTEFASNSSVLSLVNFTVDPQKAYLDFVNAGG 4272
Query 4266 QPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGK 4325
P+TNCVKML TGTG AI+V PE+ DQE++GGAS CLYCR HI+HP+ G C KGK
Sbjct 4273 APLTNCVKMLTPKTGTGIAISVKPESTADQETYGGASVCLYCRAHIEHPDVSGVCKYKGK 4332
Query 4326 YVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCG-VS 4384
+VQIP C DPVGF L NT C VC W GYGC+CD LR+ + + S FL RV G +
Sbjct 4333 FVQIPAQCVRDPVGFCLSNTPCNVCQYWIGYGCNCDSLRQAALPQSKDSNFLKRVRGSIV 4392
Query 4385 AARLTPCGTGTSTDVVYRAFDI--YNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVK 4442
AR+ PC +G STDVV+RAFDI Y KVAG K+ KTN CRF E D++G+ LDSYFVVK
Sbjct 4393 NARIEPCSSGLSTDVVFRAFDICNYKAKVAGIGKYYKTNTCRFVELDDQGHHLDSYFVVK 4452
Query 4443 RHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRH 4502
RHTM NY+ E+ Y+L++DC AVA HDFF F VD PHI RQRLT+YTM DLVYALRH
Sbjct 4453 RHTMENYELEKHCYDLLRDCDAVAPHDFFIFDVDKVKTPHIVRQRLTEYTMMDLVYALRH 4512
Query 4503 FDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFC 4562
FD+ N + LK ILV Y CCD YF K W+DFVENP ++ VY LGERVRQ++L TV+FC
Sbjct 4513 FDQ-NSEVLKAILVKYGCCDVTYFENKLWFDFVENPSVIGVYHKLGERVRQAILNTVKFC 4571
Query 4563 DAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAA 4622
D M AG+VGVLTLDNQDLNG WYDFGDFV PG GV IVDSYYS LMP+L++T LAA
Sbjct 4572 DHMVKAGLVGVLTLDNQDLNGKWYDFGDFVITQPGSGVAIVDSYYSYLMPVLSMTDCLAA 4631
Query 4623 ESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANF 4682
E+H D D KPLI+W L +YDFT+ ++ LF++YFKYWDQTYH NC+NC DDRC+LHCANF
Sbjct 4632 ETHRDCDFNKPLIEWPLTEYDFTDYKVQLFEKYFKYWDQTYHANCVNCTDDRCVLHCANF 4691
Query 4683 NVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLV 4742
NVLF+ P T FGP+VRKIFVDGVPFVVS GYH++ELG+V N DV+LH RLS KEL++
Sbjct 4692 NVLFAMTMPKTCFGPIVRKIFVDGVPFVVSCGYHYKELGLVMNMDVSLHRHRLSLKELMM 4751
Query 4743 YAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGS 4802
YAADPAMH AS N LD RT+CFSVAALT + FQTV+PGNFN+DFYDF VSKGFFKEGS
Sbjct 4752 YAADPAMHIASSNAFLDLRTSCFSVAALTTGLTFQTVRPGNFNQDFYDFVVSKGFFKEGS 4811
Query 4803 SVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQV 4862
SV LKHFFFAQDGNAAI+DY+YY YNLPTMCDI+Q+LF +EVV+KYF+ YDGGC+NA++V
Sbjct 4812 SVTLKHFFFAQDGNAAITDYNYYSYNLPTMCDIKQMLFCMEVVNKYFEIYDGGCLNASEV 4871
Query 4863 IVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNR 4922
+VNNLDKSAG PFNK+GKAR+YY+SMSY++QD LFA TKRNVIPT+TQMNLKYAISAKNR
Sbjct 4872 VVNNLDKSAGHPFNKFGKARVYYESMSYQEQDELFAMTKRNVIPTMTQMNLKYAISAKNR 4931
Query 4923 ARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPH 4982
ARTVAGVSI STMTNRQ+HQK+LKS+AATRGAT VIGT+KFYGGW MLKT+Y DV+ PH
Sbjct 4932 ARTVAGVSILSTMTNRQYHQKMLKSMAATRGATCVIGTTKFYGGWDFMLKTLYKDVDNPH 4991
Query 4983 LMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSL 5042
LMGWDYPKCDRAMPNM RI ASL+LARKH TCC RFYRLANECAQVLSE V+CGG
Sbjct 4992 LMGWDYPKCDRAMPNMCRIFASLILARKHGTCCTTRDRFYRLANECAQVLSEYVLCGGGY 5051
Query 5043 YVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYR 5102
YVKPGGTSSGDATTAYANSVFNI QA TANV+AL+ +GNKI DK V+++Q LY +YR
Sbjct 5052 YVKPGGTSSGDATTAYANSVFNILQATTANVSALMGANGNKIVDKEVKDMQFDLYVNVYR 5111
Query 5103 NRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVF 5162
+ D +FVD++YA+L KHFSMMILSDD VVCYNS+YAA+G +A I+NFK LYYQNNVF
Sbjct 5112 STSPDPKFVDKYYAFLNKHFSMMILSDDGVVCYNSDYAAKGYIAGIQNFKETLYYQNNVF 5171
Query 5163 MSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGT 5222
MSEAKCW ETDL KGPHEFCSQHT+ +K GDD +LPYPDPSRIL AGCFVDDIVKTDGT
Sbjct 5172 MSEAKCWVETDLKKGPHEFCSQHTLYIKDGDDGYFLPYPDPSRILSAGCFVDDIVKTDGT 5231
Query 5223 LMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTS 5282
LM+ERFVSLAIDAYPLTKH + EY +VF +YLQYI KL+ +LTGHMLD YSVML DN++
Sbjct 5232 LMVERFVSLAIDAYPLTKHEDIEYQNVFWVYLQYIEKLYKDLTGHMLDSYSVMLCGDNSA 5291
Query 5283 RYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKL 5342
++WE FY +Y+ T LQAVG+CV+C+SQTSLRCG CIRRPFLCCKCCYDHVI+T HK+
Sbjct 5292 KFWEEAFYRDLYSSPTTLQAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHVIATPHKM 5351
Query 5343 VLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSD 5402
VLSV+PYVCNAPGC V+DVT+LYLGGMSY+C H+P SFPLCANG VFGLYKN C GS
Sbjct 5352 VLSVSPYVCNAPGCGVSDVTKLYLGGMSYFCVDHRPVCSFPLCANGLVFGLYKNMCTGSP 5411
Query 5403 NVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDR 5462
++ +FN +ATCDWT +GDY LANT TE LKLFAAETL+ATEE K SY IAT++E++ +R
Sbjct 5412 SIVEFNRLATCDWTESGDYTLANTTTEPLKLFAAETLRATEEASKQSYAIATIKEIVGER 5471
Query 5463 ELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNV 5522
+L L WE GK +PPLNRNYVFTGY +TKNSKVQ+GEY FE+ DY DAV Y+ +TTYKL V
Sbjct 5472 QLLLVWEAGKSKPPLNRNYVFTGYHITKNSKVQLGEYIFERIDYSDAVSYKSSTTYKLTV 5531
Query 5523 GDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQ 5582
GD FVLTSH+V L+APT+V QE YV+ITGLYPT+ + +EF+S+VAN+QK G KY T+Q
Sbjct 5532 GDIFVLTSHSVATLTAPTIVNQERYVKITGLYPTITVPEEFASHVANFQKSGYSKYVTVQ 5591
Query 5583 GPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVE 5642
GPPGTGKSHFAIGLA+YYP+AR+VYTACSHAAVDALCEKA KYL I KCSRIIPA+ARVE
Sbjct 5592 GPPGTGKSHFAIGLAIYYPTARVVYTACSHAAVDALCEKAFKYLNIAKCSRIIPAKARVE 5651
Query 5643 CFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGD 5702
C+D+FKVN T QY+F T+NALPET+ADI+V DE+SM TNYDLS++NAR++AKH VY+GD
Sbjct 5652 CYDRFKVNETNSQYLFSTINALPETSADILVVDEVSMCTNYDLSIINARIKAKHIVYVGD 5711
Query 5703 PAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKL 5762
PAQLPAPRTLLT+GTLEPE FNSV RLM +GPD+FL C RCP EIV TVSALVY+NKL
Sbjct 5712 PAQLPAPRTLLTRGTLEPENFNSVTRLMCNLGPDIFLSMCYRCPKEIVSTVSALVYNNKL 5771
Query 5763 KAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAV 5822
A K+ S QCFK+ YKG +THD SSAINRPQ+ V+ F+T NPAW KAVFISPYNSQNAV
Sbjct 5772 LAKKELSGQCFKILYKGNVTHDASSAINRPQLTFVKNFITANPAWSKAVFISPYNSQNAV 5831
Query 5823 ASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDL 5882
A +LGL TQTVDSSQGSEY YVIF QT +TAH+ N+NRFNVAITRA+ GILC+M+ + L
Sbjct 5832 ARSMLGLTTQTVDSSQGSEYQYVIFCQTADTAHANNINRFNVAITRAQKGILCVMTSQAL 5891
Query 5883 YDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKT-EGLC 5941
++ L+FT L LQ++ VTGLFKDCS+ +GL P APT++SVD K+KT + LC
Sbjct 5892 FESLEFTELSFTNYK---LQSQIVTGLFKDCSRETSGLSPAYAPTYVSVDDKYKTSDELC 5948
Query 5942 VDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRD 6001
V++ +P ++ Y R+IS MGFK++ V GYP +FITREEA+R VR+WIGFDVEG HA+R+
Sbjct 5949 VNL-NLPANVPYSRVISRMGFKLDATVPGYPKLFITREEAVRQVRSWIGFDVEGAHASRN 6007
Query 6002 AVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPW 6061
A GTN+PLQLGFSTGVN V P G VDTE T + A+PPPG+QFKHL+PLM+KG W
Sbjct 6008 ACGTNVPLQLGFSTGVNFVVQPVGVVDTEWGNMLTGIAARPPPGEQFKHLVPLMHKGAAW 6067
Query 6062 NVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFST 6121
+VR +IVQMLSDTL LSD FV WAHGFELTS YF KIG E+ CC+C++RA +S+
Sbjct 6068 PIVRRRIVQMLSDTLDKLSDYCTFVCWAHGFELTSASYFCKIGKEQKCCMCNRRAAAYSS 6127
Query 6122 SSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRC 6181
+YACW HS G+DYVYNPF +DVQQWG+ GNL +NHD++C VH AHVAS DAIMTRC
Sbjct 6128 PLQSYACWTHSCGYDYVYNPFFVDVQQWGYVGNLATNHDRYCSVHQGAHVASNDAIMTRC 6187
Query 6182 LAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIK 6241
LA+H CF++RVDW +EYP I E ++NS CR V+ VV++ALLA F ++DIGNPK I
Sbjct 6188 LAIHSCFIERVDWDIEYPYISHEKKLNSCCRIVERNVVRAALLAGSFDKVYDIGNPKGIP 6247
Query 6242 CVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVC 6301
V V+W ++DAQP + K+++LFY+ +F DG+CLFWNCNV +YP NAIVC
Sbjct 6248 IVDDPVVDWHYFDAQPLTR---KVQQLFYT-EDMASRFADGLCLFWNCNVPKYPNNAIVC 6303
Query 6302 RFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGK-Q 6360
RFDTRV S NLPGCDGGSLYVNKHAFHTPA+D SAF +LK LPFFYYS +PCE HG
Sbjct 6304 RFDTRVHSEFNLPGCDGGSLYVNKHAFHTPAYDVSAFRDLKPLPFFYYSTTPCEVHGNGS 6363
Query 6361 VVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYN 6420
++ DIDYVPLKSA CIT CNLGGAVCR HA EYR+Y++AYN++ ++GF LW YK FD YN
Sbjct 6364 MIEDIDYVPLKSAVCITACNLGGAVCRKHATEYREYMEAYNLVSASGFRLWCYKTFDIYN 6423
Query 6421 LWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPV 6480
LW+TFT++Q LEN+A+N V +GHF G GE PV+++N+ ++TK D+ +FENKTTLP
Sbjct 6424 LWSTFTKVQGLENIAFNFVKQGHFIGVEGELPVAVVNDKIFTKSGVNDICMFENKTTLPT 6483
Query 6481 NVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKP 6540
N+AFEL+AKR ++ P+ K+L+NL DI V+WDY+R +TIGVC TDI
Sbjct 6484 NIAFELYAKRAVRSHPDFKLLHNLQADICYKFVLWDYERSNIYGTATIGVCKYTDI---- 6539
Query 6541 TESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGES 6600
S+L + FD R G ++ F + N + I++ +K GP A NG +
Sbjct 6540 --DVNSALNICFDIRDNGSLEKFMSTPNAIFISDRKIKKYPCMVGPDYAYFNGAIIRDSD 6597
Query 6601 VKTQ---FNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLE 6657
V Q F +KKV+ E +TQSR DF P S ME DFL D FI++Y LE
Sbjct 6598 VVKQPVKFYLYKKVNNEFIDPTECIYTQSRSCSDFLPLSDMEKDFLSFDSDVFIKKYGLE 6657
Query 6658 GYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSS 6717
YAFEH+VYGDFSH LGGLHL+IGL K+ Q+ + +E+ + ST+ NYFIT+ T +
Sbjct 6658 NYAFEHVVYGDFSHTTLGGLHLLIGLYKKQQEGHIIMEEMLKGSSTIHNYFITETNTAAF 6717
Query 6718 KCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQAS 6777
K VCSVIDL LDDFV I+KSQDL V+SKVVKV ID I FMLWCKDG V+TFYP+LQAS
Sbjct 6718 KAVCSVIDLKLDDFVMILKSQDLGVVSKVVKVPIDLTMIEFMLWCKDGQVQTFYPRLQAS 6777
Query 6778 QAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVP 6837
W+PG AMP+L+K+Q + LE+C+L NY ++ +P+G+ MN+AKY QLCQYLNT TLAVP
Sbjct 6778 ADWKPGHAMPSLFKVQNVNLERCELANYKQSIPMPRGVHMNIAKYMQLCQYLNTCTLAVP 6837
Query 6838 YNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTAN 6897
NMRVIHFGAGSDKG+APGT+VLRQWLPT +++D+DLN+FVSDAD TL GDC TV
Sbjct 6838 ANMRVIHFGAGSDKGIAPGTSVLRQWLPTDAIIIDNDLNEFVSDADITLFGDCVTVRVGQ 6897
Query 6898 KWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYK 6957
+ DL+ISDMYDP TK+VT N+SK FFTYLC I LALGGS+A+KITEHSW+ +LY+
Sbjct 6898 QVDLVISDMYDPTTKNVTGSNESKALFFTYLCNLINNNLALGGSVAIKITEHSWSVELYE 6957
Query 6958 LMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSY 7017
LMG F+WWT F TN NASSSE FL+G NYLG KE IDG MHANYIFWRN+ P+ LS+Y
Sbjct 6958 LMGKFAWWTVFCTNANASSSEGFLLGINYLGTIKENIDGGAMHANYIFWRNSTPMNLSTY 7017
Query 7018 SLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
SLFD+SKF LKL+GT V+ LKE+QIN+++ SLL +G+L+IR+N+ + VS+D+LVN
Sbjct 7018 SLFDLSKFQLKLKGTPVLQLKESQINELVISLLSQGKLLIRDNDTLSVSTDVLVN 7072
Score = 306 bits (783), Expect = 7e-81, Method: Compositional matrix adjust.
Identities = 307/1186 (26%), Positives = 515/1186 (43%), Gaps = 155/1186 (13%)
Query 101 GITLGVLVPHVGETPIAYRNVLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQN 160
G +G+ P+ E +N+LLRK G GG+ Y Y+ + + ++D+E +
Sbjct 123 GKPIGMFFPYDIELVTGKQNILLRKYGR---GGYHY--TPFHYERDNTSCPEWMDDFEAD 177
Query 161 WNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAG-KSMCTLSEQL 219
K+ L++L GG VT VD CG DG P+ +A+ G + + +
Sbjct 178 PKGKYAQNLLKKLI----GGDVTP-VDQYMCGVDGKPISAYAFLMAKDGITKLADVEADV 232
Query 220 DYIESKRGVYCCRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNS 279
G +++ + + W ER D Y Q+ F I S + D + P + F L
Sbjct 233 AARADDEGFITLKNNLYRLVWHVERKDVPYPKQSIFTINSVVQKDGVENTPPHY-FTLGC 291
Query 280 KVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN---MHLSTLMKCNHCDEVSWQTCDF 336
K+ + PR + + + +Y + N ++ S ++C C SW T +
Sbjct 292 KILTLTPRNKWSGVSDLSLKQKLLYTFYGKESLENPTYIYHSAFIECGSCGNDSWLTGNA 351
Query 337 LKATCEHCGTENLVIEGPT-TCGYLPTNAVVKMPCPACQDPEIGP--EHSVADYHNHSNI 393
++ CG + + G + NA++ CP + +HSVA ++ +
Sbjct 352 IQGFACGCGASYTANDVEVQSSGMIKPNALLCATCPFAKGDSCSSNCKHSVAQLVSYLSE 411
Query 394 ETRLRKGGR--TRCFGGCVFAYVGCYNKRAYWVPRASADIG----SGHTGITG--DNVET 445
+ + T FGG +AY GC Y+VPRA + + S TG TG + V
Sbjct 412 RCNVIADSKSFTLIFGGVAYAYFGCEEGTMYFVPRAKSVVSRIGDSIFTGCTGSWNKVTQ 471
Query 446 LNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVES 505
+ LE + + ++N VG+F +N+ V IL+ + + +K + + +
Sbjct 472 IANMFLE---QTQHSLNFVGEFVVNDVVLAILSGTTTNVDKIRQLLKGVTLDKLRDYLAD 528
Query 506 CGNYKVTKGKPVKGAWNIG----QQRSVLTP---LCGFPSQAAGV------IRSIFARTL 552
+ VT G + A N+G Q ++ P L G V + + TL
Sbjct 529 Y-DVAVTAGPFMDNAINVGGTGLQYAAITAPYVVLTGLGESFKKVATIPYKVCNSVKDTL 587
Query 553 DAANHSIPDLQRAAVTILD-GISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQ 611
HS+ L R +D G+S S L D + DL SV ++ L +T
Sbjct 588 TYYAHSV--LYRVFPYDMDSGVSSFSELLFDCV----DL---SVASTYFLVRLLQDKTGD 638
Query 612 WLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNI 671
++S ++ + + + + A FL D + + + + V + +
Sbjct 639 FMSTIITSCQTAVSKLLDTCFEATEATFNFLLDLAGLFRIFLRNAYVYTSQGFVVVNGKV 698
Query 672 KDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLG--EVFIAQSKGLYRQCIRGK---EQ 726
VK +D++NK +++ +V+ AG+ + ++ E I S Y + K +
Sbjct 699 STLVKQVLDLLNKGMQLLHTKVSWAGSNISAVIYSGRESLIFPSGTYYCVTTKAKSVQQD 758
Query 727 LQLLMPLK-APKEVTFLEGDSHDTVLTSE------EVVLKNGELEALETPVDSFTNGAIV 779
L +++P + + K++ L+ + T ++ E V+ E + +P IV
Sbjct 759 LDVILPGEFSKKQLGLLQPTDNSTTVSVTVSSNMVETVVGQLEQTNMHSP------DVIV 812
Query 780 GTPVCVNGLMLLEIKDKEQYCALSPGLL---ATNNVFRLKGGAPIKGVTFGEDTVWEVQG 836
G V ++ + + K+++ + A P A +FRLKGGAP+K V FG D V EV
Sbjct 813 GDYVIISEKLFVRSKEEDGF-AFYPACTNGHAVPTLFRLKGGAPVKKVAFGGDQVHEVAA 871
Query 837 YKNVRITFELDERVDKVL-NEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMG 895
++V + + + +D +L + + V+ + EFA VV E V L LL M
Sbjct 872 VRSVTVEYNIHAVLDTLLASSSLRTFVVDKSLSIEEFADVVKEQVSDLL---VKLLRGMP 928
Query 896 I---DLDEWSVATFYLFDDAGEENFSSRMYCSFYPP--DEE---------EEDDAECEEE 941
I DLD++ A Y F+ G+ ++SS M S +P DEE EE ++EC E
Sbjct 929 IPDFDLDDFIDAPCYCFNAEGDASWSSTMIFSLHPVECDEECSEVEASDLEEGESECISE 988
Query 942 EIDETCEHEYGTEDDY------QGLPLEFGASAETVRVEEEEE--------------EDW 981
E + + DD + PL+ A T V+EE + D
Sbjct 989 TSTEQVDVSHEISDDEWAAAVDEAFPLD-EAEDVTESVQEEAQPVEVPVEDIAQVVIADT 1047
Query 982 LDDT---TEQSEIEPEPEPTPEEP------------------------------------ 1002
L +T ++ E+ P+ P EP
Sbjct 1048 LQETPVVSDTVEVPPQVVKLPSEPQTIQPEVKEVAPVYEADTEQTQSVTVKPKRLRKKRN 1107
Query 1003 VNQFTGYLK--LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGA 1060
V+ + + +T+ V I D ++ A+ V+VNAAN HLKHGGG+AGA+N A+ GA
Sbjct 1108 VDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINAASKGA 1167
Query 1061 MQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQD 1120
+QKESD+YI GPL VG S LL GH+LAK LHVVGP+ A +D+ LL Y+ N+
Sbjct 1168 VQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKAMNAYP 1227
Query 1121 ILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVM 1166
+++ PL+SAGIFG KP S ++ +T+V + VN + +Y+ + +
Sbjct 1228 LVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTI 1273
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 5451 bits (14140), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2785/5621 (50%), Positives = 3707/5621 (66%), Gaps = 186/5621 (3%)
Query 1545 IKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL 1604
+ + TVD N + V + +G+ G + DG +VTK K +N++GK FF D L
Sbjct 1565 VDILLTVDGVNFTNRFVPVGENFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQF---DNL 1621
Query 1605 RSE---AFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
SE A D+ L Y + L + KW+ G + K A+NNC+++ L LQ
Sbjct 1622 SSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQ 1681
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
L +KF QEA+ R+G A F +L+LA G+ D R+ + + +L A
Sbjct 1682 SLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGA 1741
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
+ CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG+ + V+ + F
Sbjct 1742 ICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPF 1799
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S PA KL +G AN + G+ + GHY H+ +++ D +++ K+++ G ++
Sbjct 1800 LICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLS 1857
Query 1842 DVFYKETSYTTTIKPV--SYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLP 1898
D Y + + T K V +Y LD V E +P L YY YYT++ I T
Sbjct 1858 DCLYLK-NLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKV 1916
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL D LN GF + E VT +P GDVV Y ++
Sbjct 1917 DGVYTNFKLI--GHTICDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYE 1974
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFEVLAVEDTQGMDNL 2016
+G KP++W ++ + + + +P+ N F+VL V+D ++
Sbjct 1975 RGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFDVLKVDDVDDGGDI 2025
Query 2017 ACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAY 2076
+ ES S+E+ I+ ++ K +V +VI+ +K + L D+ +
Sbjct 2026 S-ESDAKESKEI---NIIKLSGVK---KPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMW 2078
Query 2077 VENTSITIKKPNELSLALGLKTI---ATHGIAAINSVPWSKI-LAYVKPFLGQAAITTSN 2132
+ ++ N+LS+A+ + TI G+ + S+P + L +KP N
Sbjct 2079 LTGCRYVVRTANDLSMAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVF--------N 2129
Query 2133 CAKRLAQRVFN--NYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
K + ++ N++ ++F LLF + + T +A K KL A
Sbjct 2130 VVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---KLTCKLVALA 2182
Query 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSYCNGVRELYL 2248
N + K+S + A + + + + I F L G P++ + +
Sbjct 2183 FKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIAQWIK 2242
Query 2249 NSSNVTTM-------------DFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK-LD 2294
++ ++ T+ +C GS C CL+G D LD+Y A++ +Q +D
Sbjct 2243 STFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVD 2302
Query 2295 LT-ILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQM 2351
T +L + E +++Y L+T +FY L +Q+ + F+ ++ W + ++S+ M
Sbjct 2303 YTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLANM 2362
Query 2352 APVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSF 2411
P +R YI ASF ++ + H+ GC+ C+ CYKRNR+ RV+C+TIV GM R +
Sbjct 2363 LPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIRYY 2422
Query 2412 YVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2471
V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V V
Sbjct 2423 DVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTDV 2482
Query 2472 AVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAS 2531
+ L++++ GQ+TY+ S FV+ NL + KG ++V+V + + D++
Sbjct 2483 KQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVENDA--DKANF 2540
Query 2532 KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVA 2591
+A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V + L AL+A
Sbjct 2541 LNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIA 2600
Query 2592 TAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNF 2650
TAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE+T +SCNN
Sbjct 2601 TAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCNNL 2660
Query 2651 MLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAA 2710
+ TY K +N+ DLG I +A+H+ VAK VS IW+V + LS + +++ A
Sbjct 2661 VPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKAC 2720
Query 2711 KKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYI---- 2766
K + +LT V+V+TT SLKGG + S +C L +LVC+I
Sbjct 2721 CKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSY-------FVYVCFLLSLVCFIGLWC 2773
Query 2767 VMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKN 2824
+MP +T+ D YK + +GV RD+ D CFANK FD W+ G Y N
Sbjct 2774 LMPTYTVHKSDFQLPVYTSYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2825 DKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSD 2884
+CP+V A++ +++G V +P VLR LHF+ SA G CYTP I YS+
Sbjct 2834 SMACPIVVAVVDQDLGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2885 FATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SIIQFPN 2943
F S CVL++ CT+F A G P PYCY L++ + YS L P RY L + I+FP
Sbjct 2893 FYASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGFIRFPE 2952
Query 2944 TYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNL 3003
EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG D +L
Sbjct 2953 VLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3004 IANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFL 3063
I +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWC 3072
Query 3064 MSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVF 3123
++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W +Y+
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIS 3132
Query 3124 CISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNR 3183
+ H W F Y R R+ + + TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVF-AYCR-RLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3184 YLALYNKYKYFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSG 3242
YL+LYNKY+Y+SG +DT +YREAAC LAKA++ F+ N+G+DVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3243 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKS 3302
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3303 NHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSP 3362
+ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3363 SGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFY 3422
G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3423 GPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3482
GP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQV 3488
Query 3483 TQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSG 3542
D V + L++ TG+++ + AA+K L+NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3543 VTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACA 3602
+ Q K ++VKG W++ + I+ +W++F +V N L T + + + A
Sbjct 3546 IKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLA 3604
Query 3603 MLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVM 3661
MLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y D V+
Sbjct 3605 MLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3662 YASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN 3720
Y L++ ++ +T R++ D + + VI++V Y G+ L++ I + ++ S+
Sbjct 3664 YGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGT 3721
Query 3721 YSGVVTTIMFLARAIV-FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3779
Y+ M A+ I +V V L F ++ +++ Y F+GY CY+GLF L+N
Sbjct 3722 YTWTTALSMAAAKVIAKWVAVNV--LYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNS 3779
Query 3780 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3839
FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+ QSK+
Sbjct 3780 LFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKL 3839
Query 3840 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3899
+DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL +
Sbjct 3840 TDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANP 3899
Query 3900 GAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EV 3952
AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G + +
Sbjct 3900 AAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQ 3959
Query 3953 VLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFT 4012
LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+
Sbjct 3960 QLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFS 4019
Query 4013 MLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASAL 4072
M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TYA +
Sbjct 4020 MVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNV 4079
Query 4073 WEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMS 4130
W+IQ + D+D QL+EI S + WPL++ A R N SA LQNNEL P L+
Sbjct 4080 WQIQTIQDSDGTNKQLNEI----SDDCNWPLVIIANRHNEVSATVLQNNELMPAKLKTQV 4135
Query 4131 CAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPC 4190
+G QT T YYNNS G+ V A+LSD LK+ + K DG + EL+PPC
Sbjct 4136 VNSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPC 4192
Query 4191 RFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFA 4250
+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+
Sbjct 4193 KFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFS 4252
Query 4251 VDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCH 4310
VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+YCR
Sbjct 4253 VDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIYCRAR 4312
Query 4311 IDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQS 4370
++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS
Sbjct 4313 VEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQS 4370
Query 4371 ADASTFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKD 4429
D + FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRFQ D
Sbjct 4371 KD-TNFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRFQRVD 4429
Query 4430 EEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLT 4489
E G+ LD +FVVKR ++ Y E Y VKDC VA HDFF F V+G VPHI R+ LT
Sbjct 4430 ENGDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKDLT 4489
Query 4490 KYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGE 4549
KYTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY LG
Sbjct 4490 KYTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKLGP 4549
Query 4550 RVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSL 4609
++L+ +F D + + G+VG+LTLDNQDLNG WYDFGD+V APGCGV I DSYYS
Sbjct 4550 IFNRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYYSY 4609
Query 4610 LMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCIN 4669
+MP+LT+ AL E +++ +DL++YDFT+ +L LF++YFK+W YHPN ++
Sbjct 4610 MMPMLTMCHALDCELYVN----NAYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNTVD 4665
Query 4670 CLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVN 4729
C DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N DV+
Sbjct 4666 CQDDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMDVD 4725
Query 4730 LHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFY 4789
H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+DFY
Sbjct 4726 THRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQDFY 4785
Query 4790 DFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF 4849
DF +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF
Sbjct 4786 DFILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYF 4845
Query 4850 DCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTIT 4909
+ YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+T
Sbjct 4846 EIYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLT 4905
Query 4910 QMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHN 4969
QMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +
Sbjct 4906 QMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDD 4965
Query 4970 MLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECA 5029
ML+ + DV+ P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ S RFYRLANECA
Sbjct 4966 MLRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLANECA 5025
Query 5030 QVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV 5089
QVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D +
Sbjct 5026 QVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDLSI 5085
Query 5090 RNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIK 5149
R LQ RLY +YR+ VD FV E+Y +L KHFSMMILSDD VVCYNS+YA++G +A+I
Sbjct 5086 RALQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIANIS 5145
Query 5150 NFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGA 5209
F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYPDPSRILGA
Sbjct 5146 AFQQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPDPSRILGA 5205
Query 5210 GCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHML 5269
GCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +L
Sbjct 5206 GCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLGNQIL 5265
Query 5270 DMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCK 5329
D YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCK
Sbjct 5266 DSYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCK 5325
Query 5330 CCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQ 5389
CCYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L NG
Sbjct 5326 CCYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGM 5385
Query 5390 VFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLS 5449
VFGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK S
Sbjct 5386 VFGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFKQS 5445
Query 5450 YGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDA 5509
Y AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K + +
Sbjct 5446 YASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELTNG 5505
Query 5510 VVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNV 5567
V YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +NV
Sbjct 5506 VYYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQNNV 5562
Query 5568 ANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLP 5627
NYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L
Sbjct 5563 VNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLN 5622
Query 5628 IDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSV 5687
I+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV
Sbjct 5623 INDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYELSV 5682
Query 5688 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5747
+NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RCP
Sbjct 5683 INARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRCPK 5742
Query 5748 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5807
EIVDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL NP W
Sbjct 5743 EIVDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANPLW 5802
Query 5808 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAIT 5867
KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAIT
Sbjct 5803 HKAVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAIT 5862
Query 5868 RAKIGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKIITGLHPTQAP 5926
RAK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP AP
Sbjct 5863 RAKKGILCVMSNMQLFEALQFTTLTLDKVPQAVETRVQCSTNLFKDCSKSYSGYHPAHAP 5922
Query 5927 THLSVDIKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHV 5985
+ L+VD K+K G GI +TY RLIS+MGFK++ ++GY +FIT+EEA++ V
Sbjct 5923 SFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEAVKRV 5982
Query 5986 RAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPG 6045
RAW+GFD EG HATRD++GTN PLQLGFSTG++ V TG + F + AK PPG
Sbjct 5983 RAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAKAPPG 6042
Query 6046 DQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGP 6105
+QFKHLIPLM +G W+VVR +IVQM +D L LSD VV V WA FELT ++YF K+G
Sbjct 6043 EQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFAKVGR 6102
Query 6106 ERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQV 6165
E +C +C KRAT +++ + Y CW HSV DY+YNP ++D+QQWG+ G+L SNHD +C V
Sbjct 6103 EISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDLYCSV 6162
Query 6166 HGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLA 6225
H AHVAS DAIMTRCLAV++CF ++W+VEYPII +EL +N++CR +Q +++K+A+L
Sbjct 6163 HKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKAAMLC 6222
Query 6226 DKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCL 6285
+++ + +DIGNPKAI CV + ++KFYDAQP ++ L YS+ H D F DG+C+
Sbjct 6223 NRYTLCYDIGNPKAIACVK--DFDFKFYDAQPIVK---SVKTLLYSFEAHKDSFKDGLCM 6277
Query 6286 FWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLP 6345
FWNCNVD+YP NA+VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +LK +P
Sbjct 6278 FWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHLKPMP 6337
Query 6346 FFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMIS 6405
FFYYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR+YL++YN +
Sbjct 6338 FFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYNTATT 6397
Query 6406 AGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVD 6465
AGF+ W+YK FD YNLWNTFT+LQSLENV YN+V GH+ G AGE P +IIN+ V K+D
Sbjct 6398 AGFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKID 6457
Query 6466 GIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHV 6525
DV IF N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY RE+
Sbjct 6458 KEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCS 6517
Query 6526 STIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKG 6585
+T GVC TD+ L VLFDGR G ++ F+ + NGV I+ VK L+ KG
Sbjct 6518 NTYGVCMYTDL------KFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKG 6571
Query 6586 PAQASVNGVTL--IGES---------------VKTQFNYFK-----------------KV 6611
P +A +NGV + +G++ + +QF+ + V
Sbjct 6572 PPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNV 6631
Query 6612 DGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSH 6671
G T FTQSR + F R+ ME DF+ L D FIQ+Y LE YAFEHIVYG+F+
Sbjct 6632 GGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDLFIQKYGLEDYAFEHIVYGNFNQ 6691
Query 6672 GQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDF 6731
+GGLHL+IGL +R Q S L +++F+ DS++ +YFITD ++G SK VC+VID+LLDDF
Sbjct 6692 KIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDF 6751
Query 6732 VEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYK 6791
V ++KS +L+ +SKVV V +D+ + FMLWC D V TFYP+LQA+ W+PG +MP LYK
Sbjct 6752 VALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMPVLYK 6811
Query 6792 MQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDK 6851
+E+ L NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGS+K
Sbjct 6812 YLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSEK 6871
Query 6852 GVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRT 6911
GVAPG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMYDP T
Sbjct 6872 GVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMYDPIT 6931
Query 6912 KHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTN 6971
K++ + N SK+GFFTY+C I+ KLALGGS+A+KITE SWNA+LYKLMG+F++WT F TN
Sbjct 6932 KNIGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTVFCTN 6991
Query 6972 VNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRG 7031
NASSSE FLIG NYLGKPK +IDG MHANY+FWRN+ +YSLFDM+KFPLKL G
Sbjct 6992 ANASSSEGFLIGINYLGKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPLKLAG 7051
Query 7032 TAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
TAV++L+ +QINDM+YSLLEKG+L++R+ N+ V D LVN
Sbjct 7052 TAVINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDSLVN 7092
Score = 84.0 bits (206), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 51/155 (33%), Positives = 78/155 (50%), Gaps = 2/155 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPN--LNAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
GIF SL + T QV + N++ ++ +
Sbjct 1393 GIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFDLI 1427
Score = 73.9 bits (180), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 77/286 (27%), Positives = 129/286 (45%), Gaps = 36/286 (13%)
Query 729 LLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVC- 784
L MP KA ++ +L+G D L V + L TP ++ V +C
Sbjct 763 LTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSL----TPC-GYSEPPKVADKICI 817
Query 785 VNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-KNVRI 842
V+ + + + DK + + + +R+ + VTF E TV E+ K +++
Sbjct 818 VDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAG--RRVTFKEQPTVNEIASTPKTIKV 875
Query 843 TFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLL---TNMGIDLD 899
+ELD+ + +LN C V+ V+ ++ EF VV +A+ + L P +L + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVVDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 900 EWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQG 959
+ + +LFD+AGEE +S++YC+F P EDD EE ++E T+
Sbjct 936 KLEDNSLFLFDEAGEEVLASKLYCAFTAP----EDDDFLEESGVEEDDVEGEETD----- 986
Query 960 LPLEFGASAETVRVEEEEE-----EDWLDD----TTEQSEIEPEPE 996
L ++ E E+EE ED LDD T S++E + E
Sbjct 987 --LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVE 1030
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 5449 bits (14135), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2785/5621 (50%), Positives = 3706/5621 (66%), Gaps = 186/5621 (3%)
Query 1545 IKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL 1604
+ + TVD N + V + ++G+ G + DG +VTK K +N++GK FF D L
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQF---DNL 1621
Query 1605 RSE---AFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
SE A D+ L Y + L + KW+ G + K A+NNC+++ L LQ
Sbjct 1622 SSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQ 1681
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
L +KF QEA+ R+G A F +L+LA G+ D R+ + + +L A
Sbjct 1682 SLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGA 1741
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
+ CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG+ + V+ + F
Sbjct 1742 ICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPF 1799
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S PA KL +G AN + G+ + GHY H+ +++ D +++ K+++ G ++
Sbjct 1800 LICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLS 1857
Query 1842 DVFYKETSYTTTIKPV--SYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLP 1898
D Y + + T K V +Y LD V E P L YY YYT++ I T
Sbjct 1858 DCLYLK-NLKQTFKSVLTTYYLDDVKKIEYNPDLSQYYCDGGKYYTQRIIKAQFKTFEKV 1916
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL D LN GF + E VT +P GDVV Y ++
Sbjct 1917 DGVYTNFKLI--GHTICDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYE 1974
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFEVLAVEDTQGMDNL 2016
+G KP++W ++ + + + +P+ N F+VL V+D ++
Sbjct 1975 RGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFDVLKVDDVDDGGDI 2025
Query 2017 ACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAY 2076
+ ES S+E+ I+ ++ K +V +VI+ +K + L D+ +
Sbjct 2026 S-ESDAKESKEI---NIIKLSGVK---KPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMW 2078
Query 2077 VENTSITIKKPNELSLALGLKTI---ATHGIAAINSVPWSKI-LAYVKPFLGQAAITTSN 2132
+ ++ N LS+A+ + TI G+ + S+P + L +KP N
Sbjct 2079 LTGCRYVVRTANALSMAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVF--------N 2129
Query 2133 CAKRLAQRVFN--NYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
K + ++ N++ ++F LLF + + T +A K KL A
Sbjct 2130 VVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---KLTCKLVALA 2182
Query 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSYCNGVRELYL 2248
N + K+S + A + + + + I F L G P++ + +
Sbjct 2183 FKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIAQWIK 2242
Query 2249 NSSNVTTM-------------DFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK-LD 2294
++ ++ T+ +C GS C CL+G D LD+Y A++ +Q +D
Sbjct 2243 STFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVD 2302
Query 2295 LT-ILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQM 2351
T +L + E +++Y L+T +FY L +Q+ + F+ ++ W + ++S+ M
Sbjct 2303 YTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLANM 2362
Query 2352 APVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSF 2411
P +R YI ASF ++ + H+ GC+ C+ CYKRNR+ RV+C+TIV GM R +
Sbjct 2363 LPAHVFMRFYIIIASFIKLFILFRHVAYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIRYY 2422
Query 2412 YVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2471
V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V V
Sbjct 2423 DVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTDV 2482
Query 2472 AVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAS 2531
+ L++++ GQ+TY+ S FV+ NL + KG ++V+V + + D++
Sbjct 2483 KQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVENDA--DKANF 2540
Query 2532 KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVA 2591
+A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V + L AL+A
Sbjct 2541 LNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIA 2600
Query 2592 TAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNF 2650
TAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE+T +SCNN
Sbjct 2601 TAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCNNL 2660
Query 2651 MLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAA 2710
+ TY K +N+ DLG I +A+H+ VAK VS IW+V + LS + +++ A
Sbjct 2661 VPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKAC 2720
Query 2711 KKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYI---- 2766
K + +LT V+V+TT SLKGG + S +C L +LVC+I
Sbjct 2721 CKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSY-------FVYVCFLLSLVCFIGLWC 2773
Query 2767 VMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKN 2824
+MP +T+ D YK + +GV RD+ D CFANK FD W+ G Y N
Sbjct 2774 LMPTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2825 DKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSD 2884
+CP+V A++ +++G V +P VLR LHF+ SA G CYTP I YS+
Sbjct 2834 SMACPIVVAVVDQDLGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2885 FATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SIIQFPN 2943
F S CVL++ CT+F A G P PYCY L++ + YS L P RY L + I+FP
Sbjct 2893 FYASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGFIRFPE 2952
Query 2944 TYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNL 3003
EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG D +L
Sbjct 2953 VLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3004 IANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFL 3063
I +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWC 3072
Query 3064 MSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVF 3123
++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W +Y+
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIS 3132
Query 3124 CISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNR 3183
+ H W F Y R R+ + + TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVF-AYCR-RLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3184 YLALYNKYKYFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSG 3242
YL+LYNKY+Y+SG +DT +YREAAC LAKA++ F+ N+G+DVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3243 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKS 3302
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3303 NHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSP 3362
+ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3363 SGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFY 3422
G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3423 GPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3482
GP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQV 3488
Query 3483 TQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSG 3542
D V + L++ TG+++ + AA+K L+NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3543 VTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACA 3602
+ Q K ++VKG W++ + I+ +W++F +V N L T + + + A
Sbjct 3546 IKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLA 3604
Query 3603 MLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVM 3661
MLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y D V+
Sbjct 3605 MLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVI 3663
Query 3662 YASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN 3720
Y L++ ++ +T R++ D + + VI++V Y G+ L++ I + ++ S+
Sbjct 3664 YGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGT 3721
Query 3721 YSGVVTTIMFLARAIV-FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3779
Y+ M A+ I +V V L F ++ +++ Y F+GY CY+GLF L+N
Sbjct 3722 YTWTTALSMAAAKVIAKWVAVNV--LYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNS 3779
Query 3780 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3839
FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+ QSK+
Sbjct 3780 LFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKL 3839
Query 3840 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3899
+DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL +
Sbjct 3840 TDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANP 3899
Query 3900 GAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EV 3952
AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G + +
Sbjct 3900 AAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGSANQQ 3959
Query 3953 VLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFT 4012
LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+
Sbjct 3960 QLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFS 4019
Query 4013 MLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASAL 4072
M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TYA +
Sbjct 4020 MVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNV 4079
Query 4073 WEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMS 4130
W+IQ + D+D QL+EI S + WPL++ A R N SA LQNNEL P L+
Sbjct 4080 WQIQTIQDSDGTNKQLNEI----SDDCNWPLVIIANRHNEVSATVLQNNELMPAKLKTQV 4135
Query 4131 CAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPC 4190
+G QT T YYNNS G+ V A+LSD LK+ + K DG + EL+PPC
Sbjct 4136 VNSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPC 4192
Query 4191 RFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFA 4250
+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+
Sbjct 4193 KFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFS 4252
Query 4251 VDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCH 4310
VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+YCR
Sbjct 4253 VDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIYCRAR 4312
Query 4311 IDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQS 4370
++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS
Sbjct 4313 VEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQS 4370
Query 4371 ADASTFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKD 4429
D + FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRFQ D
Sbjct 4371 KD-TNFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRFQRVD 4429
Query 4430 EEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLT 4489
E G+ LD +FVVKR ++ Y E Y VKDC VA HDFF F V+G VPHI R+ LT
Sbjct 4430 ENGDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKDLT 4489
Query 4490 KYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGE 4549
KYTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY LG
Sbjct 4490 KYTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKLGP 4549
Query 4550 RVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSL 4609
++L+ +F D + + G+VG+LTLDNQDLNG WYDFGD+V APGCGV I DSYYS
Sbjct 4550 IFNRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYYSY 4609
Query 4610 LMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCIN 4669
+MP+LT+ AL E +++ +DL++YDFT+ +L LF++YFK+W YHPN ++
Sbjct 4610 MMPMLTMCHALDCELYVN----NAYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNTVD 4665
Query 4670 CLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVN 4729
C DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N DV+
Sbjct 4666 CQDDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMDVD 4725
Query 4730 LHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFY 4789
H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+DFY
Sbjct 4726 THRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQDFY 4785
Query 4790 DFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF 4849
DF +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF
Sbjct 4786 DFILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYF 4845
Query 4850 DCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTIT 4909
+ YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+T
Sbjct 4846 EIYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLT 4905
Query 4910 QMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHN 4969
QMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +
Sbjct 4906 QMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDD 4965
Query 4970 MLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECA 5029
ML+ + DV+ P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ S RFYRLANECA
Sbjct 4966 MLRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLANECA 5025
Query 5030 QVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV 5089
QVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D +
Sbjct 5026 QVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDLSI 5085
Query 5090 RNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIK 5149
R LQ RLY +YR+ VD FV E+Y +L KHFSMMILSDD VVCYNS+YA++G +A+I
Sbjct 5086 RALQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIANIS 5145
Query 5150 NFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGA 5209
F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYPDPSRILGA
Sbjct 5146 AFQQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPDPSRILGA 5205
Query 5210 GCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHML 5269
GCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +L
Sbjct 5206 GCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLGNQIL 5265
Query 5270 DMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCK 5329
D YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCK
Sbjct 5266 DSYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCK 5325
Query 5330 CCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQ 5389
CCYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L NG
Sbjct 5326 CCYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGM 5385
Query 5390 VFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLS 5449
VFGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK S
Sbjct 5386 VFGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFKQS 5445
Query 5450 YGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDA 5509
Y AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K + +
Sbjct 5446 YASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELTNG 5505
Query 5510 VVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNV 5567
V YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +NV
Sbjct 5506 VYYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQNNV 5562
Query 5568 ANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLP 5627
NYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L
Sbjct 5563 VNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLN 5622
Query 5628 IDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSV 5687
I+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV
Sbjct 5623 INDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYELSV 5682
Query 5688 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5747
+NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RCP
Sbjct 5683 INARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRCPK 5742
Query 5748 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5807
EIVDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL NP W
Sbjct 5743 EIVDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANPLW 5802
Query 5808 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAIT 5867
KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAIT
Sbjct 5803 HKAVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAIT 5862
Query 5868 RAKIGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKIITGLHPTQAP 5926
RAK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP AP
Sbjct 5863 RAKKGILCVMSNMQLFEALQFTTLTLDKVPQAVETRVQCSTNLFKDCSKSYSGYHPAHAP 5922
Query 5927 THLSVDIKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHV 5985
+ L+VD K+K G GI +TY RLIS+MGFK++ ++GY +FIT+EEA++ V
Sbjct 5923 SFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEAVKRV 5982
Query 5986 RAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPG 6045
RAW+GFD EG HATRD++GTN PLQLGFSTG++ V TG + F + AK PPG
Sbjct 5983 RAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAKAPPG 6042
Query 6046 DQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGP 6105
+QFKHLIPLM +G W+VVR +IVQM +D L LSD VV V WA FELT ++YF K+G
Sbjct 6043 EQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFAKVGR 6102
Query 6106 ERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQV 6165
E +C +C KRAT +++ + Y CW HSV DY+YNP ++D+QQWG+ G+L SNHD +C V
Sbjct 6103 EISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDLYCSV 6162
Query 6166 HGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLA 6225
H AHVAS DAIMTRCLAV++CF ++W+VEYPII +EL +N++CR +Q +++K+A+L
Sbjct 6163 HKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKAAMLC 6222
Query 6226 DKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCL 6285
+++ + +DIGNPKAI CV + ++KFYDAQP ++ L YS+ H D F DG+C+
Sbjct 6223 NRYTLCYDIGNPKAIACVK--DFDFKFYDAQPIVK---SVKTLLYSFEAHKDSFKDGLCM 6277
Query 6286 FWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLP 6345
FWNCNVD+YP NA+VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +LK +P
Sbjct 6278 FWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHLKPMP 6337
Query 6346 FFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMIS 6405
FFYYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR+YL++YN +
Sbjct 6338 FFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYNTATT 6397
Query 6406 AGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVD 6465
AGF+ W+YK FD YNLWNTFT+LQSLENV YN+V GH+ G AGE P +IIN+ V K+D
Sbjct 6398 AGFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKID 6457
Query 6466 GIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHV 6525
DV IF N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY RE+
Sbjct 6458 KEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCS 6517
Query 6526 STIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKG 6585
+T GVC TD+ L VLFDGR G ++ F+ + NGV I+ VK L+ KG
Sbjct 6518 NTYGVCMYTDL------KFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIKG 6571
Query 6586 PAQASVNGVTL--IGES---------------VKTQFNYFK-----------------KV 6611
P +A +NGV + +G++ + +QF+ + V
Sbjct 6572 PPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNV 6631
Query 6612 DGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSH 6671
G T FTQSR + F R+ ME DF+ L D FIQ+Y LE YAFEHIVYG+F+
Sbjct 6632 GGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDLFIQKYGLEDYAFEHIVYGNFNQ 6691
Query 6672 GQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDF 6731
+GGLHL+IGL +R Q S L +++F+ DS++ +YFITD ++G SK VC+VID+LLDDF
Sbjct 6692 KIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDF 6751
Query 6732 VEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYK 6791
V ++KS +L+ +SKVV V +D+ + FMLWC D V TFYP+LQA+ W+PG +MP LYK
Sbjct 6752 VALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMPVLYK 6811
Query 6792 MQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDK 6851
+E+ L NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGS+K
Sbjct 6812 YLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSEK 6871
Query 6852 GVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRT 6911
GVAPG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMYDP T
Sbjct 6872 GVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMYDPIT 6931
Query 6912 KHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTN 6971
K++ + N SK+GFFTY+C I+ KLALGGS+A+KITE SWNA+LYKLMG+F++WT F TN
Sbjct 6932 KNIGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTVFCTN 6991
Query 6972 VNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRG 7031
NASSSE FLIG NYLGKPK +IDG MHANY+FWRN+ +YSLFDM+KFPLKL G
Sbjct 6992 ANASSSEGFLIGINYLGKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPLKLAG 7051
Query 7032 TAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
TAV++L+ +QINDM+YSLLEKG+L++R+ N+ V D LVN
Sbjct 7052 TAVINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDSLVN 7092
Score = 84.0 bits (206), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 51/155 (33%), Positives = 78/155 (50%), Gaps = 2/155 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPN--LNAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
GIF SL + T QV + N++ ++ +
Sbjct 1393 GIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFDLI 1427
Score = 73.6 bits (179), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 77/286 (27%), Positives = 129/286 (45%), Gaps = 36/286 (13%)
Query 729 LLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVC- 784
L MP KA ++ +L+G D L V + L TP ++ V +C
Sbjct 763 LTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSL----TPC-GYSEPPKVADKICI 817
Query 785 VNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-KNVRI 842
V+ + + + DK + + + +R+ + VTF E TV E+ K +++
Sbjct 818 VDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAG--RRVTFKEQPTVNEIASTPKTIKV 875
Query 843 TFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLL---TNMGIDLD 899
+ELD+ + +LN C V+ V+ ++ EF VV +A+ + L P +L + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 900 EWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQG 959
+ + +LFD+AGEE +S++YC+F P EDD EE ++E T+
Sbjct 936 KLEDNSLFLFDEAGEEVLASKLYCAFTAP----EDDDFLEESGVEEDDVEGEETD----- 986
Query 960 LPLEFGASAETVRVEEEEE-----EDWLDD----TTEQSEIEPEPE 996
L ++ E E+EE ED LDD T S++E + E
Sbjct 987 --LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVE 1030
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 5437 bits (14103), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2787/5623 (50%), Positives = 3697/5623 (66%), Gaps = 189/5623 (3%)
Query 1545 IKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL 1604
+ + TVD N + V + ++G+ G + DG +VTK K +N++GK FF D L
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQF---DNL 1621
Query 1605 RSE---AFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
SE A D+ L Y + L + KW+ G + K A+NNC+++ L LQ
Sbjct 1622 SSEDLKAVRSSFNFDQKELLAYYNMLVNCFKWQVVVNGKYFTFKQANNNCFVNVSCLMLQ 1681
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
L + F QEA+ R+G A F AL+LA G+ D R+ + + +L A
Sbjct 1682 SLHLTFKIVQWQEAWLEFRSGRPARFVALVLAKGGFKFGDPADSRDFLRVVFSQVDLTGA 1741
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
+ CK CG K TG++AVM+ GTLS ++L+ G ++ C CG+ + V+ + F
Sbjct 1742 ICDFEIACK-CGVKQEQRTGLDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPF 1799
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S PA KL +G AN + G+ GHY H+ +++ D +++ K+++ G ++
Sbjct 1800 LICSNTPASVKLPKGVG-SANIFIGD-NVGHYVHVKCEQSYQLYDASNVKKVTDVTGKLS 1857
Query 1842 DVFYKETSYTTTIKPV--SYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLP 1898
D Y + + T K V +Y LD V E +P L YY YYT++ I T
Sbjct 1858 DCLYLK-NLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKV 1916
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL D LN GF + E +T +P GDVV + Y ++
Sbjct 1917 DGVYTNFKLI--GHTVCDSLNSKLGFDSSKEFVEYKITEWPTATGDVVLANDDLYVKRYE 1974
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLA 2017
+G KP++W ++ K + T+ R L VD N F+VL V+D + +
Sbjct 1975 RGCITFGKPVIWLSHE---KASLNSLTYFNRPLL----VD-DNKFDVLKVDDVDDSGDSS 2026
Query 2018 CESQQPTSE-EVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAY 2076
+ T E +++ ++K +V +VI+ K + L D+ +
Sbjct 2027 ESGAKETKEINIIKLSGVKKPF--------KVEDSVIVNDDTSETKYVKSLSIVDVYDMW 2078
Query 2077 VENTSITIKKPNELSLALGLKTI---ATHGIAAINSVPWSKI-LAYVKPFLGQAAITTSN 2132
+ ++ N LS A+ + TI G+ + S+P + L +KP A+
Sbjct 2079 LTGCKYVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKP-----AVNVVK 2132
Query 2133 CAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGI 2192
+ FN ++ ++F LLF + + T IA K KL A
Sbjct 2133 AVRNKTSACFN-FIKWLFVLLFGWIKISADN----KVIYTTEIAS---KLTCKLVALAFK 2184
Query 2193 NYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSYCNGVRELYLNS 2250
N + K+S + A + + + + I F L G P++ + + N+
Sbjct 2185 NAFLTFKWSMVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIAQWIKNT 2244
Query 2251 SNVTTM-------------DFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK-LDLT 2296
++ T+ +C GS C CL+G D LD+Y A++ +Q +D T
Sbjct 2245 FSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYT 2304
Query 2297 -ILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAP 2353
+L + E +++Y L+T +FY L +Q+ + F+ ++ W ++++ M P
Sbjct 2305 GVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSFRLLVALANMLP 2364
Query 2354 VSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYV 2413
+R YI ASF ++ + H+ GC+ S C+ CYKRNR+ RV+C+TIV GM R + V
Sbjct 2365 AHVFMRFYIIIASFIKLFSLFKHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRYYDV 2424
Query 2414 YANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAV 2473
ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V V
Sbjct 2425 MANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQ 2484
Query 2474 KNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKS 2533
++ L++D+ GQ+ Y+ S FV+ NL + K ++V+V + + D++ +
Sbjct 2485 VGCSMRLFYDRDGQRIYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DKANFLN 2542
Query 2534 ASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATA 2593
A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V + L AL+ATA
Sbjct 2543 AAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATA 2602
Query 2594 HSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFML 2652
HS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE+T +SCNN +
Sbjct 2603 HSSIKQGTQIYKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVP 2662
Query 2653 TYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKK 2712
TY K +N+ DLG I +A+H+ VAK VS IW+V + S + +++ A K
Sbjct 2663 TYLKSDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQFSSDFQHKLKKACCK 2722
Query 2713 NNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYI----VM 2768
+ +LT V+V+TT SLKGG + S +C + +LVC+I +M
Sbjct 2723 TGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSY-------FVYVCFVLSLVCFIGLWCLM 2775
Query 2769 PVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDK 2826
P +T+ D YK + +GV RD+ D CFANK FD W+ G Y N
Sbjct 2776 PTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNSM 2835
Query 2827 SCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFA 2886
+CP+V A+I ++ G V +P VLR LHF+ SA G CYTP I YS+F
Sbjct 2836 ACPIVVAVIDQDFGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQISYSNFY 2894
Query 2887 TSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SIIQFPNTY 2945
S CVL++ CT+F A G P PYCY L++ + YS L P RY L + I+FP
Sbjct 2895 ASGCVLSSACTMFTMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRFPEVL 2954
Query 2946 LEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIA 3005
EG VRVV T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG D +LI
Sbjct 2955 REGLVRVVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIY 3014
Query 3006 NIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMS 3065
+F L QPV L ++AS +AG I+A++V YY +K +R FG+Y VV N +++ ++
Sbjct 3015 QLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSVVFVNVIVWCVN 3074
Query 3066 FTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCI 3125
F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W +Y+ +
Sbjct 3075 FMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIAVV 3134
Query 3126 SLKHCHWFFNNYLRK---RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYN 3182
H W F+ Y RK V +G TFEE AL TF++ K+ Y KL++ L +N
Sbjct 3135 VSNHAFWVFS-YCRKLGTSVRSDG----TFEEMALTTFMITKDSYCKLKNS--LSDVAFN 3187
Query 3183 RYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNS-GADVLYQPPQTSITSAVLQS 3241
RYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F+N+ G+DVLYQPP S++++ LQS
Sbjct 3188 RYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQS 3247
Query 3242 GFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRK 3301
G KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +LL R
Sbjct 3248 GIVKMVNPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRV 3307
Query 3302 SNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGS 3361
++ F V + L V+ + M+ C+L L V N +TPKY F ++PG+TF+VLA YNG
Sbjct 3308 TSSDFTVLFDRLSLTVMSYQMRGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGK 3367
Query 3362 PSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKF 3421
P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G F
Sbjct 3368 PQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDF 3427
Query 3422 YGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEP 3481
YGP+ D Q Q D ++N LAWLYAA++N WF+ ++ DFN+ A+ +
Sbjct 3428 YGPYKDAQVVQLPIQDYIQSVNFLAWLYAAILNNCNWFIQSDKCSVEDFNVWALSNGFSQ 3487
Query 3482 LTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCS 3541
+ D V + L++ TG+++ + AA+K L +NG GR I+GS EDE TP DV +Q +
Sbjct 3488 VKSDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVYQQLA 3544
Query 3542 GVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAAC 3601
G+ Q K ++ KGT W++ + I+ +W++F +V N F T + + +
Sbjct 3545 GIKLQSKRTRLFKGTVCWIMASTFLFSCIITAFVKWTMFMYVTTNMF-SITFCALCVISL 3603
Query 3602 AMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCV 3660
AMLLVKHKH +L +++ P L T+ Y N +V ++ + WL S+ Y D V
Sbjct 3604 AMLLVKHKHLYLTMYITPVLFTLLYNNYLVVYKHTFRGYVYAWLSYYVPSVE-YTYTDEV 3662
Query 3661 MYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3719
+Y L++ ++ +T R++ D + + +I++ Y G+ L++ I + ++ S+
Sbjct 3663 IYGMLLLVGMVFVTLRSINHDLFSFIMFVGRLISVFSLWYKGSNLEEEILL--MLASLFG 3720
Query 3720 NYSGVVTTIMFLARAIV-FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLN 3778
Y+ M +A+ I +V V L F ++ ++L Y F+GY CY+GLF L+N
Sbjct 3721 TYTWTTVLSMAVAKVIAKWVAVNV--LYFTDIPQIKIVLLCYLFIGYIISCYWGLFSLMN 3778
Query 3779 RYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSK 3838
FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+ QSK
Sbjct 3779 SLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSK 3838
Query 3839 MSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSM 3898
++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D + AFEK+ LL VL +
Sbjct 3839 LTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFEKLAQLLIVLFAN 3898
Query 3899 QGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-E 3951
AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A +G + +
Sbjct 3899 PAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARFSGSANQ 3958
Query 3952 VVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLF 4011
LK+L+K+ N+AKS ++RD A+ +KLE+MAD A+T MYK+AR DK++KV SA+QTMLF
Sbjct 3959 QQLKQLEKACNIAKSAYERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLF 4018
Query 4012 TMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASA 4071
+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TYA
Sbjct 4019 SMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTYAGN 4078
Query 4072 LWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQM 4129
+W+IQ + D+D QL+EI S + WPL++ A R N SA LQNNEL P L+
Sbjct 4079 VWQIQTIQDSDGTNKQLNEI----SDDCNWPLVIIANRYNEVSATVLQNNELMPAKLKIQ 4134
Query 4130 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4189
+G QT T YYNNS G+ V A+LSD LK+ + K DG + EL+PP
Sbjct 4135 VVNSGPDQTCNTPTQC--YYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPP 4191
Query 4190 CRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAF 4249
C+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF
Sbjct 4192 CKFTVQDAKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAF 4251
Query 4250 AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC 4309
+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR
Sbjct 4252 SVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCRA 4311
Query 4310 HIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQ 4369
++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +Q
Sbjct 4312 RVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCRVCGFWRDGSCSCVS-TDTTVQ 4369
Query 4370 SADASTFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEK 4428
S D + FLNRV G S ARL PC +G STDV RAFDIYN VAG LK NCCRFQ
Sbjct 4370 SKD-TNFLNRVRGASVDARLVPCASGLSTDVQLRAFDIYNASVAGIGLHLKVNCCRFQRV 4428
Query 4429 DEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRL 4488
DE G+ LD +FVVKR ++ Y E Y VKDC VA HDFF F V+G VPHI R+ L
Sbjct 4429 DENGDKLDQFFVVKRTDLTIYNREMKCYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKDL 4488
Query 4489 TKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLG 4548
TKYTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY LG
Sbjct 4489 TKYTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKLG 4548
Query 4549 ERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYS 4608
++L+ +F D + + G+VGVLTLDNQDLNG WYDFGD+V APGCGV I DSYYS
Sbjct 4549 PIFNRALVSATEFADKLVEVGLVGVLTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYYS 4608
Query 4609 LLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCI 4668
+MP+LT+ AL E +++ +DL++YDFT+ +L LF++YFK+W YHPN +
Sbjct 4609 YIMPMLTMCHALDCELYVN----NAYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNTV 4664
Query 4669 NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDV 4728
+C DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N DV
Sbjct 4665 DCQDDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMDV 4724
Query 4729 NLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDF 4788
+ H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+DF
Sbjct 4725 DTHRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQDF 4784
Query 4789 YDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKY 4848
YDF +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KY
Sbjct 4785 YDFVLSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKY 4844
Query 4849 FDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTI 4908
F+ YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+
Sbjct 4845 FEIYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTL 4904
Query 4909 TQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWH 4968
TQMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW
Sbjct 4905 TQMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWD 4964
Query 4969 NMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANEC 5028
+ML+ + DV+ P LMGWDYPKCDRAMPN+LRI++SLVLARKH TCC+ S RFYRLANEC
Sbjct 4965 DMLRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHETCCSQSDRFYRLANEC 5024
Query 5029 AQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKY 5088
AQVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D
Sbjct 5025 AQVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDLS 5084
Query 5089 VRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASI 5148
+R LQ RLY +YR+ VD FV E+Y +L KHFSMMILSDD VVCYNS+YA++G +A+I
Sbjct 5085 IRALQKRLYSHVYRSDKVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIANI 5144
Query 5149 KNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILG 5208
F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYP+PSRILG
Sbjct 5145 SAFQQVLYYQNNVFMSESKCWVEHDINNGPHEFCSQHTMLVKMDGDDVYLPYPNPSRILG 5204
Query 5209 AGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHM 5268
AGCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL YI+KL+++L +
Sbjct 5205 AGCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLAYIKKLYNDLGNQI 5264
Query 5269 LDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCC 5328
LD YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCC
Sbjct 5265 LDSYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCC 5324
Query 5329 KCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANG 5388
KCCYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L NG
Sbjct 5325 KCCYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNG 5384
Query 5389 QVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKL 5448
VFGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK
Sbjct 5385 LVFGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFKQ 5444
Query 5449 SYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGD 5508
SY AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K + +
Sbjct 5445 SYASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELTN 5504
Query 5509 AVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSN 5566
V YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F +N
Sbjct 5505 GVYYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQNN 5561
Query 5567 VANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYL 5626
V NYQ +GM++Y T+QGPPGTGKSH AIGLA++Y +AR+VYTA SHAAVDALCEKA K+L
Sbjct 5562 VVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVFYCTARVVYTAASHAAVDALCEKAYKFL 5621
Query 5627 PIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLS 5686
I+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LS
Sbjct 5622 NINDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYELS 5681
Query 5687 VVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCP 5746
V+NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RCP
Sbjct 5682 VINARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRCP 5741
Query 5747 AEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPA 5806
EIVDTVSALVY+NKLKA + S CFK++YKGV TH+ SSA+N QI ++ +FL NP
Sbjct 5742 KEIVDTVSALVYENKLKAKNESSLLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANPL 5801
Query 5807 WRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAI 5866
W KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAI
Sbjct 5802 WHKAVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAI 5861
Query 5867 TRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKIITGLHPTQA 5925
TRAK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP A
Sbjct 5862 TRAKKGILCVMSNMQLFEALQFTTLTLDKVPQAVETKVQCSTNLFKDCSKSYSGYHPAHA 5921
Query 5926 PTHLSVDIKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRH 5984
P+ L+VD K+K G GI +TY RLIS+MGFK++ ++GY +FIT+EEA++
Sbjct 5922 PSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEAVKR 5981
Query 5985 VRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPP 6044
VRAW+GFD EG HAT D++GTN PLQLGFSTG++ V TG + F + AK PP
Sbjct 5982 VRAWVGFDAEGAHATLDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAKAPP 6041
Query 6045 GDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIG 6104
G+QFKHLIPLM +G W+VVR +IVQM +D L LSD VV V WA FELT ++YF K+G
Sbjct 6042 GEQFKHLIPLMTRGHRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFAKVG 6101
Query 6105 PERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQ 6164
E +C +C KRAT +++ + Y CW HSV DY+YNP ++D+QQWG+ G+L SNHD +C
Sbjct 6102 REISCNVCTKRATVYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDLYCS 6161
Query 6165 VHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALL 6224
VH AHVAS DAIMTRCLAV++CF ++W+VEYPII +EL +N++CR +Q +++K+A+L
Sbjct 6162 VHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVILKAAML 6221
Query 6225 ADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVC 6284
+++ + +DIGNPK I CV + ++KFYDAQP ++ L YS+ H D F DG+C
Sbjct 6222 CNRYTLCYDIGNPKGIACVK--DFDFKFYDAQPIVK---SVKTLLYSFEAHKDSFKDGLC 6276
Query 6285 LFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQL 6344
+FWNCNVD+YP NA+VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +LK +
Sbjct 6277 MFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFARAAFEHLKPM 6336
Query 6345 PFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMI 6404
PFFYYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR+YL++YN
Sbjct 6337 PFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYNTAT 6396
Query 6405 SAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKV 6464
+AGF+ W+YK FD YNLWNTFT+LQSLENV YN+V GH+ G AGE P +IIN+ V TK+
Sbjct 6397 TAGFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVVTKI 6456
Query 6465 DGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAH 6524
D DV IF N TT P NVA EL+AKR+++ PE+K+ NL +D+ VIWDY RE+
Sbjct 6457 DKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARESIFC 6516
Query 6525 VSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSK 6584
+T GVC TD+ L VLFDGR G + F+ + NGV I+ VK L+ +
Sbjct 6517 SNTYGVCMYTDL------KFIDKLNVLFDGRDNGAFEAFKRSNNGVYISTTKVKSLSMIR 6570
Query 6585 GPAQASVNGVTL--IGES-------VKTQ-----FNYFKKVDGIIQQLPE---------- 6620
GP +A +NGV + +G++ V+ + F+ F + Q P+
Sbjct 6571 GPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNGKPG 6630
Query 6621 -----------TYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDF 6669
T FTQSR + F R+ ME DF+ L D FIQ+Y LE YAFEHIVYG+F
Sbjct 6631 NVGGNDALSISTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNF 6690
Query 6670 SHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLD 6729
+ +GGLHL+IGL +R Q S L +++F+ DS++ +YFITD ++G SK VC+VID+LLD
Sbjct 6691 NQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLD 6750
Query 6730 DFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNL 6789
DFV ++KS +L+ +SKVV V +D+ + FMLWC D V TFYP+LQA+ W+PG +MP L
Sbjct 6751 DFVTLVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMPVL 6810
Query 6790 YKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGS 6849
YK +E+ L NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGS
Sbjct 6811 YKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGS 6870
Query 6850 DKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDP 6909
+KGVAPG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMYDP
Sbjct 6871 EKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMYDP 6930
Query 6910 RTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFV 6969
TK++ + N SK+GFFTY+C I+ KLALGGS+A+KITE SWNA+LYKLMG+F++WT F
Sbjct 6931 ITKNIGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTVFC 6990
Query 6970 TNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKL 7029
TN NASSSE FLIG NYL KPK +IDG MHANY+FWRN+ +YSLFDM+KFPLKL
Sbjct 6991 TNANASSSEGFLIGINYLCKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPLKL 7050
Query 7030 RGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
GTAV++L+ +QINDM+YSLLEKG+L+IR+ N+ V D LVN
Sbjct 7051 AGTAVINLRADQINDMVYSLLEKGKLLIRDTNKEVFVGDSLVN 7093
Score = 83.6 bits (205), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 51/155 (33%), Positives = 81/155 (52%), Gaps = 2/155 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ + +K
Sbjct 1273 ITPNVCFVKGDIIKVSKLVKAEVVVNPANGHMVHGGGVAKAIAVAAGQQFVKETTNMVKS 1332
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPN--LNAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G G + +G L K L+VVGP+ + LL+ Y++FN+ D ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYVLLERVYKHFNNYDCVVTTLISA 1392
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
GIF SL + T + QV + N++ ++ +
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLI 1427
Score = 68.6 bits (166), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 74/284 (26%), Positives = 126/284 (44%), Gaps = 26/284 (9%)
Query 729 LLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVC- 784
L MP KA ++ +L+G D L V + L TP ++ V +C
Sbjct 763 LTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSL----TPC-GYSEPPKVADKICI 817
Query 785 VNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-KNVRI 842
V+ + + + DK + + + +R+ + VTF E TV E+ K +++
Sbjct 818 VDNVYMAKAGDKYYPVVVDDHVGLLDQAWRVPCAG--RRVTFKEQPTVKEIISMPKIIKV 875
Query 843 TFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLL---TNMGIDLD 899
+ELD + +LN C V+ V+ ++ EF VV +A+ + L P +L + L
Sbjct 876 FYELDNDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 900 EWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQG 959
+ +LFD+AGEE F+ ++YC+F P E+DD ++E+ E E +
Sbjct 936 KLEDNPLFLFDEAGEEVFAPKLYCAFTAP---EDDDF------LEESDVEEDDVEGEETD 986
Query 960 LPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPV 1003
L + A V E+EE + L+DT + + EE V
Sbjct 987 LTIT-SAGQPCVASEQEESSEVLEDTLDDGPSVETSDSQVEEDV 1029
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 5429 bits (14083), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2786/5665 (49%), Positives = 3695/5665 (65%), Gaps = 203/5665 (4%)
Query 1526 EVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIK 1585
+V S+ ++++LL+ + V TVD N + V +G+ G + DG +VTK++
Sbjct 1543 KVASVSQIRALLA----NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR 1598
Query 1586 PHVNHEGKTFF----VLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGL 1641
H+GK FF + +D ++AF + DE L +Y + L K W G
Sbjct 1599 CSAIHKGKVFFQYSGLSAADLVAVTDAFGF----DEPQLLKYYNMLGMCK-WPVVVCGNY 1653
Query 1642 TSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGE 1701
+ K ++NNCY++ L LQ L +KF+ QEA+ R+G F +L+LA + E
Sbjct 1654 FAFKQSNNNCYINVACLMLQHLSLKFHKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNE 1713
Query 1702 LGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVS 1761
D + M +L+ A+L A VCK CG K GV+AVM+ GTL +L G +
Sbjct 1714 PSDSTDFMRVVLREADLSGATCDFEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLAKGYT 1772
Query 1762 IPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKET 1821
I C CG + Q F++ S P KL + AN +TG GHYTH+ K
Sbjct 1773 IACTCGNKLV-HCTQLNVPFLICSNKPEGKKLPDDV-VAANIFTGG-SLGHYTHVKCKPK 1829
Query 1822 LYRIDGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKD 1880
D +++K+SE KG TD Y K T + K ++ LD V E P L YY +
Sbjct 1830 YQLYDACNVSKVSEAKGNFTDCLYLKNLKQTFSSKLTTFYLDDVKCVEYNPDLSQYYCES 1889
Query 1881 NAYYTEQPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFP 1938
YYT+ I T + NFKL A+ N GF E +T +P
Sbjct 1890 GKYYTKPIIKAQFRTFEKVEGVYTNFKLV--GHSIAEKFNAKLGFDCNSPFTEYKITEWP 1947
Query 1939 DLNGDVVAIDYRHYSASFKKGAKLLHKPIVW--HINQATTKTTF--KPNTWCLRCLWSTK 1994
GDVV Y + + G KP++W H + T+ +P+ C ++
Sbjct 1948 TATGDVVLASDDLYVSRYSGGCVTFGKPVIWLGHEEASLKSLTYFNRPSVVCEN-KFNVL 2006
Query 1995 PVDTSNSFEV----LAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE---------- 2040
PVD S + AV T + A ++V + ++ +V+
Sbjct 2007 PVDVSEPTDKGPVPAAVLVTGALSGAATAPGTAKEQKVCASDSVVDQVVSGFLSDLSGAT 2066
Query 2041 CDVKTTEVVG---------NVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELS 2091
DVK ++ G +V++ KV + L D+ ++ + NELS
Sbjct 2067 VDVKEVKLNGVKKPIKVEDSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWMANELS 2126
Query 2092 LALGLKTIATHGIAAINSVPW--SKILAYVKPFLGQAAITTSNCAKRLAQRVFNNY--MP 2147
+ T+ + V W +KI+ K L + K + +V Y +
Sbjct 2127 RLVNSPTVREY-------VKWGMTKIVIPAKLVLLRDEKQEFVAPKVVKAKVIACYSAVK 2179
Query 2148 YVFTLLFQLCTF--------TKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPK 2199
+ F F F T S++ +L KN++++ + G V +
Sbjct 2180 WFFLYCFSWIKFNTDNKVIYTTEVASKLTFNLCCLAFKNALQTFNWNVVSRGFFLVAT-- 2237
Query 2200 FSKLFTIAMWLLLLSICLGSLICVTAAF---------GVLLSNFGAPSYCNGVRELYLNS 2250
+F + L ++ L F + + FG + C +LY S
Sbjct 2238 ---VFLLWFNFLYANVILSDFYLPNIGFFPTFVGQIVAWVKTTFGIFTLC----DLYQVS 2290
Query 2251 SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQ-VTISSYKLD-LTILGLAAEWVLAY 2308
FC GS C +C SG D LD+Y A+ +Q V D +++ L E V+ Y
Sbjct 2291 DVGYRSSFCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRVSFDYISLFKLVVELVIGY 2350
Query 2309 MLFTKFFY-LLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFA 2365
L+T FY L GL MQ+ + F+ + W F + + M P ++R YI
Sbjct 2351 SLYTVCFYPLFGLIG-MQLLTTWLPEFFMLETMHWSARFFVFVANMLPAFTLLRFYIVVT 2409
Query 2366 SFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTH 2425
+ Y I+ H+M GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H
Sbjct 2410 AMYKIFCLCRHVMYGCSRPGCLFCYKRNRSVRVKCSTVVGGTLRYYDVMANGGTGFCAKH 2469
Query 2426 NWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKA 2485
WNCLNC F G+TFI+ E A DLS + KRP+NPTD + Y+V V ++ L++++
Sbjct 2470 QWNCLNCSAFGPGNTFITHEAAADLSKELKRPVNPTDSAYYLVTEVKQVGCSMRLFYERD 2529
Query 2486 GQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQP 2545
GQ+ Y+ S FV+++ L + KG +V+V + ++ D++ +A+V+Y+Q + +P
Sbjct 2530 GQRVYDDVSASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRP 2587
Query 2546 ILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDG 2605
+LL+++ L++ VS MFD YVD+ V + L + V AH+ L +GV L+
Sbjct 2588 MLLVEKKLITTANTGLSVSQTMFDLYVDSLLGVLDVDRKSLTSFVNAAHNSLKEGVQLEQ 2647
Query 2606 VLSTFVSAARQG-VVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRD 2664
V+ TF+ AR+ +D+DV+TK + + + + ++ ++ T +SCNN + TY K + + D
Sbjct 2648 VMDTFIGCARRKCAIDSDVETKSITKSIMSAVNAGVDFTDESCNNLVPTYVKSDTIVAAD 2707
Query 2665 LGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATT 2724
LG I NA+H+ A VAK+ NV+ IW+V + LS L+ ++R A K + +LT
Sbjct 2708 LGVLIQNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQ 2767
Query 2725 RQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEII 2784
V ++TT SLKGG + S + + L+C + V + +MP + + D
Sbjct 2768 EANVPILTTPFSLKGGAVFSKVLQWLFVVNLICFI---VLWALMPTYAVHKSDMQLPLYA 2824
Query 2785 GYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREIGFI 2842
+K I +GV RD+ TD CFANK FD W+ G Y+N ++CPVV A+I ++IG+
Sbjct 2825 SFKVIDNGVLRDVTVTDACFANKFIQFDQWYESTFGLVYYRNSRACPVVVAVIDQDIGYT 2884
Query 2843 VPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDA 2902
+ +P VLR LHF+ F+ CYTP I Y +F S CVL++ CT+ A
Sbjct 2885 LFNVPTKVLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHA 2943
Query 2903 MGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYC 2961
G P PYCY ++ + Y L P RY L + + I+FP EG VR+V T YC
Sbjct 2944 DGTPHPYCYTEGIMHNASLYDSLAPHVRYNLANSNGYIRFPEVVSEGIVRIVRTRSMTYC 3003
Query 2962 RHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVS 3021
R G CE +E G+C + + WVLNN +YRA+ G FCG +A +LI + LV+P+ ++
Sbjct 3004 RVGLCEDAEEGVCFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALT 3063
Query 3022 ASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGV 3081
AS VAG I+AI+V A YY +K +R FG+Y VV N +++ ++F +L + Y L +
Sbjct 3064 ASSVAGAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCL 3123
Query 3082 YSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRK- 3140
Y+ FY Y T YF +++S + HLQW M+ I+P W IYV + H W F+ Y RK
Sbjct 3124 YACFYFYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFS-YCRKL 3182
Query 3141 --RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGAL 3198
V +G TFEE +L TF++ KE Y KL++ + +NRYL+LYNKY+YFSG +
Sbjct 3183 GTEVRSDG----TFEEMSLTTFMITKESYCKLKNS--VSDVAFNRYLSLYNKYRYFSGKM 3236
Query 3199 DTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3257
DT +YREAAC LAKA+ F+ N+G DVLYQPP S+T++ LQSG KM FP+ KVE C+
Sbjct 3237 DTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVFPTSKVEPCV 3296
Query 3258 VQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRV 3317
V VT G TLNGLWLDD VYCPRHVIC++ DM +P+Y +LL R + F V +G + L V
Sbjct 3297 VSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYSNLLCRVISSDFCVMSGRMSLTV 3356
Query 3318 IGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIK 3377
+ + MQ LL L V NP TPKY F ++PG+TF+VLA YNG G + MR ++TIK
Sbjct 3357 MSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGKSQGAFHVTMRSSYTIK 3416
Query 3378 GSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTD 3437
GSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q Q D
Sbjct 3417 GSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQD 3476
Query 3438 TTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQT 3497
T T+NV+AWLYAA++N WF+ + +L +FN+ AM + + D V L L++ T
Sbjct 3477 YTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMT 3534
Query 3498 GIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTH 3557
G+ V + AA+K L +G G+ ILGS +LEDE TP DV +Q +GV Q K ++VKGT
Sbjct 3535 GVTVEQILAAIKRLY-SGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVVKGTC 3593
Query 3558 HWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFL 3617
W+L + L I+ +W++F +V + L TL + + AMLLVKHKH +L +F+
Sbjct 3594 CWILASTLLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLVKHKHLYLTMFI 3652
Query 3618 LPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASAL-VLLILMTAR 3675
+P L T+ Y N +V S+ WL ++ Y D V+Y L V ++ +T R
Sbjct 3653 MPVLCTLFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLYGVVLLVAMVFVTMR 3711
Query 3676 TVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAI 3735
++ D ++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA A
Sbjct 3712 SINHDVFSVMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAK 3767
Query 3736 VFVCVEYYPLLFITG-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVST 3794
V +L+ T ++ ++L Y +GY CCCY+G+ LLN FR+ LGVY+Y +S
Sbjct 3768 VIAKWLAVNVLYFTDVPQVKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISV 3827
Query 3795 QEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQ 3854
QE RYMN+ GL PP++S +A LN KLLGIGG P I+V+ +QS+++DVKC +VVLL+ LQ
Sbjct 3828 QELRYMNANGLRPPRNSFEALVLNFKLLGIGGVPVIEVSQIQSRLTDVKCVNVVLLNCLQ 3887
Query 3855 QLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLC 3908
L + SSSKLW C LHN+IL D + AF+K+ LL VL + AVD I +
Sbjct 3888 HLHIASSSKLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVS 3947
Query 3909 EEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSE 3967
++ + + LQA+ SEF ++ S+ Y A++ ++A A+G + + +K+L+K+ N+AKS
Sbjct 3948 DDYVRDSTVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSA 4007
Query 3968 FDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIIN 4027
++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++
Sbjct 4008 YERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKLDNQALNSILD 4067
Query 4028 NARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQ 4087
NA GCVPLN IP T+ L ++VPD + D TYA +W IQ + DAD + Q
Sbjct 4068 NAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQ 4127
Query 4088 LSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNA 4145
L+EI++ N+ WPL++ A R N S+V LQNNEL P LR +G+ T
Sbjct 4128 LNEIDV----NITWPLVIAANRHNEVSSVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQC 4183
Query 4146 LAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL 4205
YYN + G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYL
Sbjct 4184 --YYNTTGMGKIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYL 4240
Query 4206 YFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGG 4265
YF+KG N L RG V+G+L++TVRLQAG ATE +NS + S CAF+VDP K Y DY+ GG
Sbjct 4241 YFVKGCNTLARGWVVGTLSSTVRLQAGTATEYASNSAIRSLCAFSVDPKKTYLDYIQQGG 4300
Query 4266 QPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGK 4325
P+TNCVKMLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK
Sbjct 4301 APVTNCVKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGK 4360
Query 4326 YVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSA 4385
+VQ+P DPV + L + VC VCG W+ CSC QS D + FLNRV G S
Sbjct 4361 FVQVPLG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVGTGSQF-QSKD-TNFLNRVRGTSV 4417
Query 4386 -ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRH 4444
ARL PC +G TDV RAFDI N AG + K NCCRFQ DE+GN LD +FV+KR
Sbjct 4418 NARLVPCASGLDTDVQLRAFDICNANRAGIGLYYKVNCCRFQRADEDGNTLDKFFVIKRT 4477
Query 4445 TMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFD 4504
+ Y E+ Y L K+C VA H+FF F V+G VPHI R+ L+KYTM DL YALRHFD
Sbjct 4478 NLEVYNKEKECYELTKECGVVAEHEFFTFDVEGSRVPHIVRKDLSKYTMLDLCYALRHFD 4537
Query 4505 EGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDA 4564
+C TLKEIL+TY CD+ YF KKDWYDFVEN DI+ VY LG ++LL T +F D
Sbjct 4538 RNDCSTLKEILLTYAECDESYFQKKDWYDFVENSDIINVYKKLGPIFNRALLNTAKFADT 4597
Query 4565 MRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAES 4624
+ +AG+VGVLTLDNQDL G WYDFGDFV+ PGCGV + DSYYS +MP+LT+ AL +E
Sbjct 4598 LVEAGLVGVLTLDNQDLYGQWYDFGDFVKTVPGCGVAVADSYYSYMMPMLTMCHALDSEL 4657
Query 4625 HMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNV 4684
++ + +DL++YDFT+ +L LF++YFKYW TYHPN C DDRCI+HCANFN+
Sbjct 4658 FINGTYRE----FDLVQYDFTDFKLELFNKYFKYWSMTYHPNTCECEDDRCIIHCANFNI 4713
Query 4685 LFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYA 4744
LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YA
Sbjct 4714 LFSMVLPKTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYA 4773
Query 4745 ADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSV 4804
ADPA+H AS + LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV
Sbjct 4774 ADPALHVASASALLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSV 4833
Query 4805 ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIV 4864
+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV+KYF+ YDGGCI A QVIV
Sbjct 4834 DLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVNKYFEIYDGGCIPATQVIV 4893
Query 4865 NNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRAR 4924
NN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRAR
Sbjct 4894 NNYDKSAGYPFNKFGKARLYYEALSFEEQDEVYAYTKRNVLPTLTQMNLKYAISAKNRAR 4953
Query 4925 TVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLM 4984
TVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LM
Sbjct 4954 TVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLM 5013
Query 4985 GWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYV 5044
GWDYPKCDRAMPN+LRI++SLVLARKH++CC+ + RFYRLANECAQVLSE+VMCGG YV
Sbjct 5014 GWDYPKCDRAMPNILRIISSLVLARKHDSCCSHTDRFYRLANECAQVLSEIVMCGGCYYV 5073
Query 5045 KPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNR 5104
KPGGTSSGDATTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR
Sbjct 5074 KPGGTSSGDATTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRAD 5133
Query 5105 DVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMS 5164
VD FV+E+Y +L KHFSMMILSDD VVCYNS +A++G +A+I F+ VLYYQNNVFMS
Sbjct 5134 HVDPAFVNEYYEFLNKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQVLYYQNNVFMS 5193
Query 5165 EAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLM 5224
EAKCW ETD+ KGPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+
Sbjct 5194 EAKCWVETDIEKGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLL 5253
Query 5225 IERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRY 5284
IERFVSLAIDAYPL H N EY +VF +YL+YI+KL+++L +LD YSV+L+ + ++
Sbjct 5254 IERFVSLAIDAYPLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSYSVILSTCDGQKF 5313
Query 5285 WEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVL 5344
+ FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VL
Sbjct 5314 TDETFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVL 5373
Query 5345 SVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNV 5404
SV+PYVCN+PGCDV DVT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS +
Sbjct 5374 SVSPYVCNSPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYI 5433
Query 5405 TDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDREL 5464
DFN IA+C WT DY+LAN CTERLKLFAAET KATEE+FK Y AT+RE++SDREL
Sbjct 5434 EDFNKIASCKWTEVDDYVLANECTERLKLFAAETQKATEESFKQCYASATIREIVSDREL 5493
Query 5465 HLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGD 5524
LSWE+GK RPPLN+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD
Sbjct 5494 ILSWEIGKVRPPLNKNYVFTGYHFTSNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGD 5553
Query 5525 YFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQ 5582
F+LTSH V LSAPTLVPQE+Y +R +Y ++ + F +NV NYQ +GM++Y T+Q
Sbjct 5554 VFILTSHAVSSLSAPTLVPQENYTSIRFASVY---SVPETFQNNVPNYQHIGMKRYCTVQ 5610
Query 5583 GPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVE 5642
GPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+
Sbjct 5611 GPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNINDCTRIVPAKVRVD 5670
Query 5643 CFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGD 5702
C+DKFKVN T +YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGD
Sbjct 5671 CYDKFKVNDTTRKYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGD 5730
Query 5703 PAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKL 5762
PAQLPAPR LL KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY NKL
Sbjct 5731 PAQLPAPRVLLNKGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYHNKL 5790
Query 5763 KAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAV 5822
KA D S+ CFK++YKG TH+ SSA+N QI ++ +FL NP+W AVFISPYNSQN V
Sbjct 5791 KAKNDNSSMCFKVYYKGQTTHESSSAVNMQQIYLISKFLKANPSWSNAVFISPYNSQNYV 5850
Query 5823 ASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDL 5882
A ++LGL TQTVDS+QGSEYD+VI++QT ETAHS NVNRFNVAITRAK GILC+MS L
Sbjct 5851 AKRVLGLQTQTVDSAQGSEYDFVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSSMQL 5910
Query 5883 YDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEG-LC 5941
++ L F++L + + N LQ T LFKDCS+ G HP AP+ L+VD K+K G L
Sbjct 5911 FESLNFSTLTLDKINNPRLQC--TTNLFKDCSRSYAGYHPAHAPSFLAVDDKYKVGGDLA 5968
Query 5942 VDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRD 6001
V + +TY RLIS+MGFK++ ++GY +FITR+EAIR VRAW+GFD EG HATRD
Sbjct 5969 VCLNVADSAVTYSRLISLMGFKLDLTLDGYCKLFITRDEAIRRVRAWVGFDAEGAHATRD 6028
Query 6002 AVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPW 6061
++GTN PLQLGFSTG++ V TG + F + A+ PPG+QFKHL+PLM +G W
Sbjct 6029 SIGTNFPLQLGFSTGIDFVVEATGMFAERDGYVFKKAVARAPPGEQFKHLVPLMSRGQKW 6088
Query 6062 NVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFST 6121
+VVRI+IVQMLSD L L+D VV V WA FELT ++YF K+G E C +C+KRATCF++
Sbjct 6089 DVVRIRIVQMLSDHLVDLADSVVLVTWAASFELTCLRYFAKVGKEVVCSVCNKRATCFNS 6148
Query 6122 SSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRC 6181
+ Y CW HS DY+YNP ++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRC
Sbjct 6149 RTGYYGCWRHSYSCDYLYNPLIVDIQQWGYTGSLTSNHDLICSVHKGAHVASSDAIMTRC 6208
Query 6182 LAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIK 6241
LAVH+CF K V+WS+EYPII +E+ VN++CR +Q ++ ++A+L +++ V +DIGNPK +
Sbjct 6209 LAVHDCFCKSVNWSLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLA 6268
Query 6242 CVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVC 6301
CV ++KFYDA P +++ Y Y H D+F DG+C+FWNCNVD+YPANA+VC
Sbjct 6269 CVKG--YDFKFYDASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVC 6323
Query 6302 RFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQV 6361
RFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC
Sbjct 6324 RFDTRVLNKLNLPGCNGGSLYVNKHAFHTSPFTRAAFENLKPMPFFYYSDTPCVYMEGME 6383
Query 6362 VSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNL 6421
+DYVPL+SATCITRCNLGGAVC HA +YR+YL++YN +AGF+ W+YK FD YNL
Sbjct 6384 SKQVDYVPLRSATCITRCNLGGAVCLKHAEDYREYLESYNTATTAGFTFWVYKTFDFYNL 6443
Query 6422 WNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVN 6481
WNTFTRLQSLENV YN+VN GHFDG AGE P ++I V K+ DV +F+N T P N
Sbjct 6444 WNTFTRLQSLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTN 6503
Query 6482 VAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPT 6541
VA EL+AKR+I+P PE+K+ NL +D+ + V+WDY +++ ST VC TD+
Sbjct 6504 VAVELFAKRSIRPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYTDL----- 6558
Query 6542 ESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTL--IGE 6599
SL VLFDGR G ++ F+ R+GV I +K L+ KGP +A +NGV + +G+
Sbjct 6559 -QCIESLNVLFDGRDNGALEAFKKCRDGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGD 6617
Query 6600 S-VKTQFNYFKKVDGII-----------QQLPE--------------------TYFTQSR 6627
S V+ F + D +I + P+ T FTQSR
Sbjct 6618 SDVEFWFAMRRDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSR 6677
Query 6628 DLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRS 6687
L F PRS+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHL+IGLA+R
Sbjct 6678 FLSSFAPRSEMEKDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRQ 6737
Query 6688 QDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVV 6747
Q S L +++F+P DS++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS +L+ +SKVV
Sbjct 6738 QKSNLVIQEFVPYDSSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKSLNLNCVSKVV 6797
Query 6748 KVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGE 6807
V +D+ + FMLWC + V TFYP+LQA+ W+PG MP LYK LE+ +L NYG+
Sbjct 6798 NVNVDFKDFQFMLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPLERVNLWNYGK 6857
Query 6808 NAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTG 6867
+P G +MNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+AVLRQWLP G
Sbjct 6858 PITLPTGCLMNVAKYTQLCQYLNTTTLAVPANMRVLHLGAGSDKDVAPGSAVLRQWLPAG 6917
Query 6868 TLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTY 6927
++LVD+D+N FVSD+ ++ G+C T+ A +WDLIISDMYDP TK++ + N SK+GFFTY
Sbjct 6918 SILVDNDINPFVSDSVASYYGNCITLPIACQWDLIISDMYDPLTKNIGEYNVSKDGFFTY 6977
Query 6928 LCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYL 6987
LC I+ KLALGGS+A+KITE SWNA+LY LMG F++WT F TNVNASSSE FLIG N+L
Sbjct 6978 LCHLIRDKLALGGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWL 7037
Query 6988 GKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIY 7047
+ + +IDG TMHANY+FWRN+ +YSLFDMSKFPLK+ GTAV+SLK +QIND++
Sbjct 7038 NRTRTEIDGKTMHANYLFWRNSTMWNGGAYSLFDMSKFPLKVAGTAVVSLKPDQINDLVL 7097
Query 7048 SLLEKGRLIIRENNRVVVSSDILVN 7072
SL+EKG+L++R+ + V D LVN
Sbjct 7098 SLIEKGKLLVRDTRKEVFVGDSLVN 7122
Score = 77.8 bits (190), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 113/464 (24%), Positives = 193/464 (42%), Gaps = 57/464 (12%)
Query 569 ILDGISEQSLRLVDA-------MVYTSDLLTNSVIIMAYVTGGLVQQTSQWLSNLLGTT- 620
+LDG+ +S L+ + MV S +T+ + MA + V+ ++++ + G
Sbjct 576 LLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMALLFMHDVKVATKYVKKVTGKLA 635
Query 621 -------VEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
V +R I EW + + W + L+ G+F + G I SD + +
Sbjct 636 VRFKALGVAVVRKITEWFDLAVDTAAS--AAGWLCYQ-LVNGLFAVANGGITFLSD-VPE 691
Query 674 CVKCFIDVVNKALEMCIDQVTIA---GAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLL 730
VK F+D ++ ID ++++ G + V +A K +Y + K +
Sbjct 692 LVKNFVDKFKVFFKVLIDSMSVSVLSGLTVVKTASNRVCLAGCK-VYE--VVQKRLSAYV 748
Query 731 MPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGEL--EALETPVDSFTNGAIVGTPVCVNGL 788
MP+ E T L G+ V+ + V + L + P SF +V + L
Sbjct 749 MPVGC-NEATCLVGEIEPAVVEDDVVDVVKAPLTYQGCCKPPTSFEKICVV------DKL 801
Query 789 MLLEIKDKEQYCAL---SPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGYKNVRITF 844
+ + D+ + + G+L F G K V F + V E+ + ++I F
Sbjct 802 YMAKCGDQFYPVVVDNDTIGVLDQCWRFPCAG----KKVEFNDKPKVKEIPSTRKIKINF 857
Query 845 ELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD---LLTNMGIDLDEW 901
LD D VL++ CS + V+ + E VV +AV TL P + + T + L+
Sbjct 858 ALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEHDVIGTKVCALLNRL 917
Query 902 SVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLP 961
+ YLFD+ GEE + +MYCSF PD+E +C ++ + E++ DD L
Sbjct 918 AEDYVYLFDEGGEEVIAPKMYCSFSAPDDE-----DCVAADVVDADENQGDDADDSAALV 972
Query 962 L----EFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEE 1001
E G + V V E + D E +IE +P E
Sbjct 973 TDTQEEDGVAKGQVGVAESDAR---LDQVEAFDIEKVEDPILNE 1013
Score = 58.2 bits (139), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 52/149 (35%), Positives = 76/149 (51%), Gaps = 2/149 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV D++K + VIVN AN + HG GVAGA+ KA + KE+ D +K
Sbjct 1267 ITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKSFIKETADMVKN 1326
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G VG +G NL K L++VGP+ + + L+ AY++ N D ++ L+SA
Sbjct 1327 QGVCQVGECYESTGGNLCKTVLNIVGPDARGHGKQCYSFLERAYQHINKCDDVVTTLISA 1386
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDK 1158
GIF SL + V V + N+K
Sbjct 1387 GIFSVPTDVSLTYLIGVVTKNVILVSNNK 1415
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 5418 bits (14054), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2772/5625 (49%), Positives = 3693/5625 (66%), Gaps = 194/5625 (3%)
Query 1545 IKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL 1604
+ + TVD N + V + ++G+ G + DG +VTK K +N++GK FF D L
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQF---DNL 1621
Query 1605 RSE---AFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
SE A D+ L Y + L + KW+ G + K A+NNC+++ L LQ
Sbjct 1622 SSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQ 1681
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
L +KF QEA+ R+G A F +L+LA G+ D R+ + + +L A
Sbjct 1682 SLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGA 1741
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
+ CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG+ + V+ + F
Sbjct 1742 ICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPF 1799
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S PA KL +G AN + G+ + GHY H+ +++ D +++ K+++ G ++
Sbjct 1800 LICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLS 1857
Query 1842 DVFYKETSYTTTIKPV--SYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLP 1898
D Y + + T K V +Y LD V E +P L YY YYT++ I T
Sbjct 1858 DCLYLK-NLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKV 1916
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL D LN GF + E VT +P GDVV Y ++
Sbjct 1917 DGVYTNFKLI--GHTVCDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYE 1974
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFEVLAVEDTQGMDNL 2016
+G KP++W ++ + + + +P+ N F+VL V+D ++
Sbjct 1975 RGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFDVLKVDDVDDGGDI 2025
Query 2017 A-CESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
+ ++++P +++ ++K +V +VI+ +K + L D+
Sbjct 2026 SESDAKEPKEINIIKLSGVKKPF--------KVEDSVIVNDDTSEIKYVKSLSIVDVYDM 2077
Query 2076 YVENTSITIKKPNELSLALGLKTI---ATHGIAAINSVPWSKI-LAYVKPFLGQAAITTS 2131
++ ++ N LS A+ + TI G+ + S+P + L +KP
Sbjct 2078 WLTGCRCVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVF-------- 2128
Query 2132 NCAKRLAQRVFN--NYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLD 2189
N K + ++ N++ ++F LLF + + T +A K KL
Sbjct 2129 NVVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---KLTCKLVAL 2181
Query 2190 AGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSYCNGVRELY 2247
A N + K+S + A + + + + I F L G P++ + +
Sbjct 2182 AFKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIAQWI 2241
Query 2248 LNSSNVTTM-------------DFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK-L 2293
N+ ++ T+ +C GS C CL+G D LD+Y A++ +Q +
Sbjct 2242 KNTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFV 2301
Query 2294 DLT-ILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQ 2350
D T +L + E +++Y L+T +FY L +Q+ + F+ ++ W + ++S+
Sbjct 2302 DYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLAN 2361
Query 2351 MAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRS 2410
M P +R YI ASF ++ + H+ GC+ S C+ CYKRNR+ RV+C+TIV GM R
Sbjct 2362 MLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRY 2421
Query 2411 FYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDS 2470
+ ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2422 YDAMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTD 2481
Query 2471 VAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESA 2530
V + L++D+ GQ+TY+ S FV+ NL + K ++V+V + + D++
Sbjct 2482 VKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DKAN 2539
Query 2531 SKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALV 2590
+A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V + L AL+
Sbjct 2540 FLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALI 2599
Query 2591 ATAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNN 2649
ATAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE+T +SCNN
Sbjct 2600 ATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCNN 2659
Query 2650 FMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSA 2709
+ TY K +N+ DLG I +A+H+ VAK VS IW+V + LS + +++ A
Sbjct 2660 LVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKA 2719
Query 2710 AKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYI--- 2766
K + +LT V+V+TT SLKGG + S +C + +LVC+I
Sbjct 2720 CCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSY-------FVYVCFVLSLVCFIGLW 2772
Query 2767 -VMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYK 2823
+MP +T+ D YK + +GV RD+ D CFANK FD W+ G Y
Sbjct 2773 CLMPTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYS 2832
Query 2824 NDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYS 2883
N +CP+V A++ ++ G V +P VLR LHF+ SA G CYTP I YS
Sbjct 2833 NSMACPIVVAVVDQDFGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQISYS 2891
Query 2884 DFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SIIQFP 2942
+F S CVL++ CT+F A G P PYCY L++ + YS L P RY L + I+FP
Sbjct 2892 NFYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRFP 2951
Query 2943 NTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMN 3002
EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG D +
Sbjct 2952 EVLREGLVRIVRTRSMPYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFD 3011
Query 3003 LIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLF 3062
LI +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N +++
Sbjct 3012 LIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVW 3071
Query 3063 LMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYV 3122
++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W +Y+
Sbjct 3072 CVNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYI 3131
Query 3123 FCISLKHCHWFFNNYLRK---RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3179
+ H W F +Y R+ V +G TFEE AL TF++ K+ Y KL++ L
Sbjct 3132 SVVVSNHAFWVF-SYCRQLGTSVRSDG----TFEEMALTTFMITKDSYCKLKNS--LSDV 3184
Query 3180 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAV 3238
+NRYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F+ N+G+DVLYQPP S++++
Sbjct 3185 AFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSF 3244
Query 3239 LQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLL 3298
LQSG KM P+ KVE C+V VT G TLNGLWL D VYCPRHVIC+A DM NP+Y +LL
Sbjct 3245 LQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDYTNLL 3304
Query 3299 IRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACY 3358
R ++ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA Y
Sbjct 3305 CRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAY 3364
Query 3359 NGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLE 3418
NG P G + MR ++TIKGSFL GSCGSV + I DCV F YMH +EL TG H GTD
Sbjct 3365 NGKPQGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMGDCVKFVYMHQLELSTGCHTGTDFN 3424
Query 3419 GKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYN 3478
G FYGP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+
Sbjct 3425 GDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNG 3484
Query 3479 YEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVR 3538
+ + D V + L++ TG+++ + AA+K L+NG GR I+GS EDE TP DV +
Sbjct 3485 FSQVKSDLV--IDALASMTGVSLETLLAAIKH-LKNGFQGRQIMGSCSFEDELTPSDVYQ 3541
Query 3539 QCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAI 3598
Q +G+ Q K ++VKG W++ + I+ +W++F +V N L T + +
Sbjct 3542 QLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCV 3600
Query 3599 AACAMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLK 3657
+ MLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y
Sbjct 3601 ISLTMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYT 3659
Query 3658 DCVMYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVIS 3716
D V+Y L++ ++ +T R++ + + VI++V Y G+ L++ I + ++ S
Sbjct 3660 DEVIYGMLLLIGMVFVTLRSINQYLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLAS 3717
Query 3717 VTSNYSGVVTTIMFLARAIV-FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
+ Y+ M A+ I +V V L F ++ +++ Y F+GY CY+GLF
Sbjct 3718 LFGTYTWTTALSMAAAKVIAKWVAVNV--LYFTDIPQIKIVLVCYLFIGYIISCYWGLFS 3775
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
L+N FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+
Sbjct 3776 LMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQF 3835
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL
Sbjct 3836 QSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVL 3895
Query 3896 LSMQGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
+ AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G
Sbjct 3896 FANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGS 3955
Query 3950 S-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQT 4008
+ + LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QT
Sbjct 3956 ANQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQT 4015
Query 4009 MLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTY 4068
MLF+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TY
Sbjct 4016 MLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 4075
Query 4069 ASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVAL 4126
A +W+IQ + D+D QL EI S + WPL++ A R N SA LQNNEL P L
Sbjct 4076 AGNVWQIQTIQDSDGTNKQLHEI----SDDCNWPLVIIANRHNEVSATALQNNELMPAKL 4131
Query 4127 RQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTEL 4186
+ +G QT T YYNNS G+ V A+LSD LK+ + K DG + EL
Sbjct 4132 KTQVVNSGPDQTCNTPTQ--CYYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LEL 4188
Query 4187 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4246
+PPC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS
Sbjct 4189 DPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSL 4248
Query 4247 CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4306
CAF+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+Y
Sbjct 4249 CAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIY 4308
Query 4307 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP 4366
CR ++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC +
Sbjct 4309 CRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDT 4366
Query 4367 LMQSADASTFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRF 4425
+QS D + FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRF
Sbjct 4367 TVQSKD-TNFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRF 4425
Query 4426 QEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISR 4485
Q DE G+ LD +FVVKR ++ Y E Y VKDC VA HDFF F V+G VPHI R
Sbjct 4426 QRVDENGDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVR 4485
Query 4486 QRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYA 4545
+ LTKYTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY
Sbjct 4486 KDLTKYTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYK 4545
Query 4546 NLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDS 4605
LG ++L+ +F D + + G+VG+LTLDNQDLNG WYDFGD+V APGCGV I DS
Sbjct 4546 KLGPIFNRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADS 4605
Query 4606 YYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHP 4665
YYS +MP+LT+ AL E +++ +DL++YDFT+ +L LF++YFK+W YHP
Sbjct 4606 YYSYMMPMLTMCHALDCELYVN----NAYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHP 4661
Query 4666 NCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHN 4725
N ++C DDRCI+ CANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N
Sbjct 4662 NTVDCQDDRCIIRCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMN 4721
Query 4726 QDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFN 4785
DV+ H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN
Sbjct 4722 MDVDTHRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFN 4781
Query 4786 KDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVV 4845
+DFYDF +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV
Sbjct 4782 QDFYDFILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVV 4841
Query 4846 DKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVI 4905
KYF+ YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+
Sbjct 4842 YKYFEIYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVL 4901
Query 4906 PTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYG 4965
PT+TQMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYG
Sbjct 4902 PTLTQMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYG 4961
Query 4966 GWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLA 5025
GW +ML+ + DV+ P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ S RFYRLA
Sbjct 4962 GWDDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLA 5021
Query 5026 NECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIA 5085
NE AQVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI
Sbjct 5022 NEYAQVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIE 5081
Query 5086 DKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLV 5145
D +R LQ RLY +YR+ VD FV E+Y +L KHFSMMILSDD VVCYNS+YA++G +
Sbjct 5082 DLSIRALQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYI 5141
Query 5146 ASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSR 5205
A+I F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYPDPSR
Sbjct 5142 ANISAFQQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPDPSR 5201
Query 5206 ILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELT 5265
ILGAGCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL++EL
Sbjct 5202 ILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNELG 5261
Query 5266 GHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPF 5325
+LD YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P
Sbjct 5262 NQILDSYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPL 5321
Query 5326 LCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLC 5385
LCCKCCYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L
Sbjct 5322 LCCKCCYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLV 5381
Query 5386 ANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEET 5445
NG VFGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE
Sbjct 5382 MNGMVFGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEA 5441
Query 5446 FKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGD 5505
FK SY AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K +
Sbjct 5442 FKQSYASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSE 5501
Query 5506 YGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEF 5563
+ V YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F
Sbjct 5502 LTNGVYYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETF 5558
Query 5564 SSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKAL 5623
+NV NYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA
Sbjct 5559 QNNVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAY 5618
Query 5624 KYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNY 5683
K+L I+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY
Sbjct 5619 KFLNINDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNY 5678
Query 5684 DLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCR 5743
+LSV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC
Sbjct 5679 ELSVINARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCY 5738
Query 5744 RCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTR 5803
RCP EIVDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL
Sbjct 5739 RCPKEIVDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKA 5798
Query 5804 NPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN 5863
NP W KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFN
Sbjct 5799 NPLWHKAVFISPYNSQNFAARRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFN 5858
Query 5864 VAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKIITGLHP 5922
VAITRAK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP
Sbjct 5859 VAITRAKKGILCVMSNMQLFEALQFTTLTVDKVPQAVETRVQCSTNLFKDCSKSYSGYHP 5918
Query 5923 TQAPTHLSVDIKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEA 5981
AP+ L+VD K+K G GI +TY RL S+MGFK++ ++GY +FIT+EEA
Sbjct 5919 AHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLTSLMGFKLDVTLDGYCKLFITKEEA 5978
Query 5982 IRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAK 6041
++ VRAW+GFD EG HATRD++GTN PLQLGFSTG++ V TG + F + AK
Sbjct 5979 VKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAK 6038
Query 6042 PPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFV 6101
PPG+QFKHLIPLM +G W+VVR +IVQM +D L LSD VV V WA FELT ++YF
Sbjct 6039 APPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFA 6098
Query 6102 KIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQ 6161
K+G E +C +C KRAT +++ + Y CW HSV DY+YNP ++D+QQWG+ G+L SNHD
Sbjct 6099 KVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDL 6158
Query 6162 HCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKS 6221
+C VH AHVAS DAIMTRCLAV++CF ++W+VEYPII +EL +N++CR +Q +++K+
Sbjct 6159 YCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKA 6218
Query 6222 ALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTD 6281
A+L +++ + +DIGNPKAI CV + ++KFYDAQP ++ L Y + H D F D
Sbjct 6219 AMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPIVK---SVKTLLYFFEAHKDSFKD 6273
Query 6282 GVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNL 6341
G+C+FWNCNVD+YP NA+VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +L
Sbjct 6274 GLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHL 6333
Query 6342 KQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYN 6401
K +PFFYYSD+PC +DYVPLKSATCITRCNL GAVC HA EYR+YL++YN
Sbjct 6334 KPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLVGAVCLKHAEEYREYLNSYN 6393
Query 6402 MMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVY 6461
+AGF+ W+YK FD YNLWNTFT+LQSLENV YN+V GH+ G AGE P +IIN+ V
Sbjct 6394 TATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVV 6453
Query 6462 TKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREA 6521
K+D DV IF N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY RE+
Sbjct 6454 AKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARES 6513
Query 6522 PAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLT 6581
+T GVC TD+ L VLFDGR G ++ F+ + NGV I+ VK L+
Sbjct 6514 IFCSNTYGVCMYTDL------KFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLS 6567
Query 6582 PSKGPAQASVNGVTL--IGES---------------VKTQFNYFK--------------- 6609
+GP +A +NGV + +G++ + +QF+ +
Sbjct 6568 MIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNE 6627
Query 6610 --KVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYG 6667
V G T FTQSR + F R+ ME DF+ L D FIQ+Y LE YAFEHIVYG
Sbjct 6628 PGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYG 6687
Query 6668 DFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLL 6727
+F+ +GGLHL+IGL +R Q S L +++F+ DS++ +YFITD ++G SK VC+VID+L
Sbjct 6688 NFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDIL 6747
Query 6728 LDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMP 6787
LDDFV ++KS +L+ +SKVV V +D+ + FMLWC D V TFY +LQA+ W+PG +MP
Sbjct 6748 LDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYLRLQAASDWKPGYSMP 6807
Query 6788 NLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGA 6847
LYK +E+ L NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GA
Sbjct 6808 VLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGA 6867
Query 6848 GSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY 6907
GS+KGVAPG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMY
Sbjct 6868 GSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMY 6927
Query 6908 DPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTA 6967
DP TK++ + N SK+GFFTY+C I+ KLALGGS+A+KITE SWNA+LYKLMG+F++WT
Sbjct 6928 DPITKNIGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTV 6987
Query 6968 FVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPL 7027
F TN NASSSE FLIG NYLGKPK +IDG MHANY+FWRN+ +YSLFDM+KFPL
Sbjct 6988 FCTNANASSSEGFLIGINYLGKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPL 7047
Query 7028 KLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
KL GTAV++L+ +QINDM+YSLLEKG+L++R+ N+ V D +VN
Sbjct 7048 KLAGTAVINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDSMVN 7092
Score = 84.7 bits (208), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 51/155 (33%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPN--LNAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
GIF SL + T + QV + N++ ++ +
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLI 1427
Score = 70.1 bits (170), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 57/197 (29%), Positives = 96/197 (49%), Gaps = 18/197 (9%)
Query 822 KGVTFGED-TVWEVQGY-KNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEA 879
+ VTF E TV E+ K +++ +ELD+ + +LN C V+ V+ ++ EF VV +A
Sbjct 853 RCVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDA 912
Query 880 VVKTLQPVSDLL---TNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDA 936
+ + L P +L + L + + +LFD+AGEE + ++YC+F P EDD
Sbjct 913 IEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLAPKLYCAFTAP----EDDD 968
Query 937 ECEEEEIDETCEHEYGTEDDYQGLPLEFGASAE-TVRVEEEEEEDWLDDTTEQSEIEPEP 995
EE ++E T+ L ++ E V E+EE + L+DT +
Sbjct 969 FLEESGVEEDDVEGEETD-------LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETS 1021
Query 996 EPTPEEPVNQFTGYLKL 1012
+ EE V Q + ++ L
Sbjct 1022 DSQVEEDV-QMSDFVDL 1037
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 5408 bits (14028), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2789/5660 (49%), Positives = 3694/5660 (65%), Gaps = 200/5660 (4%)
Query 1529 SLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHV 1588
S+ ++++LL+ + V TVD N + V +G+ G + DG +VTK++
Sbjct 1599 SVSQIRALLA----NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSA 1654
Query 1589 NHEGKTFF----VLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSI 1644
++GK FF + +D +AF + DE L +Y + L K W G +
Sbjct 1655 IYKGKVFFQYSDLSEADLVAVKDAFGF----DEPQLLKYYTMLGMCK-WPVVVCGNYFAF 1709
Query 1645 KWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGD 1704
K ++NNCY++ L LQ L +KF QEA+ R+G F +L+LA + E D
Sbjct 1710 KQSNNNCYINVACLMLQHLSLKFPKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSD 1769
Query 1705 VRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPC 1764
+ M +L+ A+L A L VCK CG K GV+AVM+ GTL +L G +I C
Sbjct 1770 SIDFMRVVLREADLSGATCNLEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLVRGYNIAC 1828
Query 1765 VCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYR 1824
CG + Q F++ S P KL + AN +TG GHYTH+ K
Sbjct 1829 TCGSKLV-HCTQFNVPFLICSNTPEGRKLPDDV-VAANIFTGG-SVGHYTHVKCKPKYQL 1885
Query 1825 IDGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAY 1883
D ++ K+SE KG TD Y K T + ++ LD V E +P L YY + Y
Sbjct 1886 YDACNVNKVSEAKGNFTDCLYLKNLKQTFSSVLTTFYLDDVKCVEYKPDLSQYYCESGKY 1945
Query 1884 YTEQPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLN 1941
YT+ I T + + NFKL A+ LN GF E +T +P
Sbjct 1946 YTKPIIKAQFRTFEKVDGVYTNFKLV--GHSIAEKLNAKLGFDCNSPFVEYKITEWPTAT 2003
Query 1942 GDVVAIDYRHYSASFKKGAKLLHKPIVW--HINQATTKTTF--KPNTWCLRCLWSTKPVD 1997
GDVV Y + + G KP+VW H + T+ +P+ C ++ PVD
Sbjct 2004 GDVVLASDDLYVSRYSSGCITFGKPVVWLGHEEASLKSLTYFNRPSVVCEN-KFNVLPVD 2062
Query 1998 TSNSFE------VLAVEDTQGMD----------NLACES---QQPTSEEVVENPTIQ--- 2035
S + + V G D AC S + EV + P++
Sbjct 2063 VSEPTDKGPVPAAVLVTGVPGADASAGAGIAKEQKACASASVEDQVVTEVRQEPSVSAAD 2122
Query 2036 -KEVIECDVKT-TEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLA 2093
KEV VK +V G+V++ KV + L D+ ++ + NELS
Sbjct 2123 VKEVKLNGVKKPVKVEGSVVVNDPTSETKVVKSLSIVDVYDMFLTGCKYVVWTANELSRL 2182
Query 2094 LGLKTIATHGIAAINSVPWS--KILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFT 2151
+ T+ + V W KI+ K L + K + + Y +
Sbjct 2183 VNSPTVREY-------VKWGMGKIVTPAKLLLLRDEKQEFVAPKVVKAKAIACYCAVKWF 2235
Query 2152 LLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFS----KLFTIA 2207
LL+ +T++++ + T +A K KLC A N +++ +S F +A
Sbjct 2236 LLYCFSWIKFNTDNKVIYT--TEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVA 2290
Query 2208 MWLLLLSICLGSLICVTAAFGVLLSNFGA-PSYCNGVRELYLNSSNVTTM---------- 2256
LL L + + ++ + L N G P++ + + + V+T+
Sbjct 2291 TVFLLWFNFLYANVILSDFY---LPNIGPLPTFVGQIVAWFKTTFGVSTICDFYQVTDLG 2347
Query 2257 ---DFCEGSFPCSICLSGLDSLDSYPALETIQ-VTISSYKLD-LTILGLAAEWVLAYMLF 2311
FC GS C +C SG D LD+Y A+ +Q V D +++ L E V+ Y L+
Sbjct 2348 YRSSFCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRLSFDYISLFKLVVELVIGYSLY 2407
Query 2312 TKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFASFYY 2369
T FY L + MQ+ + F+ + W + + M P ++R YI + Y
Sbjct 2408 TVCFYPLFVLIGMQLLTTWLPEFFMLETMHWSARLFVFVANMLPAFTLLRFYIVVTAMYK 2467
Query 2370 IWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNC 2429
++ H+M GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC
Sbjct 2468 VYCLCRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNC 2527
Query 2430 LNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKT 2489
LNC+++ G+TFI+ E A DLS + KRP+NPTD + Y V V ++ L++++ GQ+
Sbjct 2528 LNCNSWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVTEVKQVGCSMRLFYERDGQRV 2587
Query 2490 YERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLL 2549
Y+ S FV+++ L + KG +V+V + ++ D++ A+V+Y+Q + +P+L++
Sbjct 2588 YDDVNASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLGAAVFYAQSLYRPMLMV 2645
Query 2550 DQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLST 2609
++ L++ VS MFD YVD+ V + L + V AH+ L +GV L+ V+ T
Sbjct 2646 EKKLITTANTGLSVSRTMFDLYVDSLLNVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDT 2705
Query 2610 FVSAARQG-VVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGAC 2668
F+ AR+ +D+DV+TK + + + + ++ ++ T +SCNN + TY K + + DLG
Sbjct 2706 FIGCARRKCAIDSDVETKSITKSVMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGVL 2765
Query 2669 IDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVV 2728
I NA+H+ A VAK+ NV+ IW+V + LS L+ ++R A K + +LT V
Sbjct 2766 IQNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEANV 2825
Query 2729 NVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKA 2788
++TT SLKGG + S + + A L+C + V + +MP + + D +K
Sbjct 2826 PILTTPFSLKGGAVFSRMLQWLFVANLICFI---VLWALMPTYAVHKSDMQLPLYASFKV 2882
Query 2789 IQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREIGFIVPGL 2846
I +GV RD+ TD CFANK FD W+ G Y+N K+CPVV A+I ++IG + +
Sbjct 2883 IDNGVLRDVSVTDACFANKFNQFDQWYESTFGLAYYRNSKACPVVVAVIDQDIGHTLFNV 2942
Query 2847 PGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKP 2906
P TVLR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P
Sbjct 2943 PTTVLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTP 3001
Query 2907 VPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRHGT 2965
PYCY ++ + YS L P RY L + I+FP EG VRVV T YCR G
Sbjct 3002 HPYCYTGGVMHNASLYSSLAPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGL 3061
Query 2966 CERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVV 3025
CE +E GIC + + WVLNN +YRA+ G FCG +A +LI + LV+P+ ++AS V
Sbjct 3062 CEEAEEGICFNFNRSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASSV 3121
Query 3026 AGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVF 3085
AG I+AI+V A YY +K +R FG+Y VV N +++ ++F +L + Y L +Y+ F
Sbjct 3122 AGAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACF 3181
Query 3086 YLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRK---RV 3142
Y Y T YF +++S + HLQW M+ I+P W IYV + H W F+ Y RK V
Sbjct 3182 YFYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFS-YCRKIGTEV 3240
Query 3143 MFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTS 3202
+G TFEE AL TF++ KE Y KL++ + +NRYL+LYNKY+YFSG +DT +
Sbjct 3241 RSDG----TFEEMALTTFMITKESYCKLKNS--VSDVAFNRYLSLYNKYRYFSGKMDTAA 3294
Query 3203 YREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVT 3261
YREAAC LAKA+ F+ N+G DVLYQPP S+T++ LQSG KM P+ KVE C+V VT
Sbjct 3295 YREAACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCIVSVT 3354
Query 3262 CGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHS 3321
G TLNGLWLDD VYCPRHVIC++ DM +P+Y +LL R ++ F V +G + L V+ +
Sbjct 3355 YGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSGRMSLTVMSYQ 3414
Query 3322 MQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFL 3381
MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + +R +HTIKGSFL
Sbjct 3415 MQGCQLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVTLRSSHTIKGSFL 3474
Query 3382 NGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTIT 3441
GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q Q D T T
Sbjct 3475 CGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQT 3534
Query 3442 LNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAV 3501
+NV+AWLYAA+ N WF+ + +L +FN+ AM + + D V L L++ TG+ V
Sbjct 3535 VNVVAWLYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTV 3592
Query 3502 LDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWML 3561
+ AA+K L +G G+ ILGS +LEDE TP DV +Q +GV Q K +++KGT W+L
Sbjct 3593 EQVLAAIKRL-HSGFQGKQILGSCVLEDE-TPSDVYQQLAGVKLQSKRTRVIKGTCCWIL 3650
Query 3562 LTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSL 3621
+ I+ +W++F +V + L TL + + AMLL+KHKH +L ++++P L
Sbjct 3651 ASTFLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLIKHKHLYLTMYIMPVL 3709
Query 3622 ATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASAL-VLLILMTARTVYDD 3680
T +V S+ WL ++ Y D V+Y L V ++ +T R++ D
Sbjct 3710 CTFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLYGVVLLVAMVFVTMRSINHD 3768
Query 3681 AARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCV 3740
++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA A V
Sbjct 3769 VFSIMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKW 3824
Query 3741 EYYPLLFITG-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRY 3799
+L+ T ++ ++L Y +GY CCCY+G+ LLN FR+ LGVY+Y +S QE RY
Sbjct 3825 LAVNVLYFTDVPQIKLVLLSYLCIGYVCCCYWGILSLLNSIFRMPLGVYNYKISVQELRY 3884
Query 3800 MNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVE 3859
MN+ GL PP++S +A LN KLLGIGG P I+V+ +QS+++DVKC +VVLL+ LQ L +
Sbjct 3885 MNANGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIA 3944
Query 3860 SSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLCEEMLD 3913
S+SKLW C LHN+IL D + AF+K+ LL VL + AVD I + ++ +
Sbjct 3945 SNSKLWQYCSTLHNEILATSDLSMAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVR 4004
Query 3914 NRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDA 3972
+ LQA+ SEF ++ S+ Y A++ ++A A+G + + +K+L+K+ N+AKS ++RD
Sbjct 4005 DNTVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDR 4064
Query 3973 AMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDG 4032
A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA G
Sbjct 4065 AVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKG 4124
Query 4033 CVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEIN 4092
CVPLN IP T+ L ++VPD + D TYA +W IQ + DAD + QL+EI+
Sbjct 4125 CVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEID 4184
Query 4093 MDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN 4150
++++ WPL++ A R N S V LQNNEL P LR +G+ T YYN
Sbjct 4185 VNST----WPLVIAANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQC--YYN 4238
Query 4151 NSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKG 4210
+ G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG
Sbjct 4239 TTGTGKIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKG 4297
Query 4211 LNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITN 4270
N L RG V+G+L++TVRLQAG ATE +NS +LS CAF+VDP K Y DY+ GG P+TN
Sbjct 4298 CNTLARGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIKQGGVPVTN 4357
Query 4271 CVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIP 4330
CVKMLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4358 CVKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVP 4417
Query 4331 TTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSA-ARLT 4389
DPV + L + VC VCG W+ CSC QS D + FLNR+ G S ARL
Sbjct 4418 LG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVGTGSQF-QSKD-TNFLNRIRGTSVNARLV 4474
Query 4390 PCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNY 4449
PC +G TDV RAFDI N AG + K NCCRFQ DE+GN LD +FVVKR + Y
Sbjct 4475 PCASGLDTDVQLRAFDICNANRAGIGLYYKVNCCRFQRVDEDGNKLDKFFVVKRTNLEVY 4534
Query 4450 QHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCD 4509
E+ Y L K+C VA H+FF F V+G VPHI R+ L+K+TM DL YALRHFD +C
Sbjct 4535 NKEKECYELTKECGVVAEHEFFTFDVEGSRVPHIVRKDLSKFTMLDLCYALRHFDRNDCS 4594
Query 4510 TLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAG 4569
TLKEIL+TY C++ YF KKDWYDFVENPDI+ VY LG ++LL T +F DA+ +AG
Sbjct 4595 TLKEILLTYAECEESYFQKKDWYDFVENPDIINVYKKLGPIFNRALLNTAKFADALVEAG 4654
Query 4570 IVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDAD 4629
+VGVLTLDNQDL G WYDFGDFV+ PGCGV + DSYYS +MP+LT+ AL +E ++
Sbjct 4655 LVGVLTLDNQDLYGQWYDFGDFVKTVPGCGVAVADSYYSYMMPMLTMCHALDSELFVNGT 4714
Query 4630 LAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTV 4689
+ +DL++YDFT+ +L LF +YFK+W TYHPN C DDRCI+HCANFN+LFS V
Sbjct 4715 YRE----FDLVQYDFTDFKLELFTKYFKHWSMTYHPNTCECEDDRCIIHCANFNILFSMV 4770
Query 4690 FPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAM 4749
P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YAADPA+
Sbjct 4771 LPKTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYAADPAL 4830
Query 4750 HAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHF 4809
H AS + LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV+LKHF
Sbjct 4831 HVASASALLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSVDLKHF 4890
Query 4810 FFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDK 4869
FF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV+KYF+ Y+GGCI A QVIVNN DK
Sbjct 4891 FFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVNKYFEIYEGGCIPATQVIVNNYDK 4950
Query 4870 SAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGV 4929
SAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGV
Sbjct 4951 SAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGV 5010
Query 4930 SICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYP 4989
SI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYP
Sbjct 5011 SILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYP 5070
Query 4990 KCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGT 5049
KCDRAMPN+LRI++SLVLARKH++CC+ + RFYRLANECAQVLSE+VMCGG YVKPGGT
Sbjct 5071 KCDRAMPNILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLSEIVMCGGCYYVKPGGT 5130
Query 5050 SSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHE 5109
SSGDATTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD
Sbjct 5131 SSGDATTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPA 5190
Query 5110 FVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCW 5169
FV E+Y +L KHFSMMILSDD VVCYNS +A++G +A+I F+ VLYYQNNVFMSEAKCW
Sbjct 5191 FVSEYYEFLNKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQVLYYQNNVFMSEAKCW 5250
Query 5170 TETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFV 5229
ETD+ KGPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFV
Sbjct 5251 VETDIEKGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFV 5310
Query 5230 SLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEF 5289
SLAIDAYPL H N EY +VF +YL+YI+KL+++L +LD YSV+L+ + ++ + F
Sbjct 5311 SLAIDAYPLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSYSVILSTCDGQKFTDETF 5370
Query 5290 YEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPY 5349
Y+ MY VLQ+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VLSV+PY
Sbjct 5371 YKNMYLRSAVLQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPY 5430
Query 5350 VCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNA 5409
VCN+PGCDV DVT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS + DFN
Sbjct 5431 VCNSPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNK 5490
Query 5410 IATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWE 5469
IA+C WT DY+LAN CTERLKLFAAET KATEE FK Y AT+RE++SDREL LSWE
Sbjct 5491 IASCKWTEVDDYVLANECTERLKLFAAETQKATEEAFKQCYASATIREIVSDRELILSWE 5550
Query 5470 VGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLT 5529
+GK RPPLN+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD F+LT
Sbjct 5551 IGKVRPPLNKNYVFTGYHFTNNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFILT 5610
Query 5530 SHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGT 5587
SH V LSAPTLVPQE+Y +R +Y ++ + F +NV NYQ +GM++Y T+QGPPGT
Sbjct 5611 SHAVSSLSAPTLVPQENYTSIRFASVY---SVPETFQNNVPNYQHIGMKRYCTVQGPPGT 5667
Query 5588 GKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKF 5647
GKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+C+DKF
Sbjct 5668 GKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAHKFLNINDCTRIVPAKVRVDCYDKF 5727
Query 5648 KVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLP 5707
KVN T +YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGDPAQLP
Sbjct 5728 KVNDTTRKYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGDPAQLP 5787
Query 5708 APRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD 5767
APR LL KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA D
Sbjct 5788 APRVLLNKGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYNNKLKAKND 5847
Query 5768 KSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL 5827
S+ CFK++YKG TH+ SSA+N QI ++ +FL NP+W AVFISPYNSQN VA ++L
Sbjct 5848 NSSMCFKVYYKGQTTHESSSAVNMQQIHLISKFLKANPSWSNAVFISPYNSQNYVAKRVL 5907
Query 5828 GLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQ 5887
GL TQTVDS+QGSEYD+VI++QT ETAHS NVNRFNVAITRAK GILC+MS L++ L
Sbjct 5908 GLQTQTVDSAQGSEYDFVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSSMQLFESLN 5967
Query 5888 FTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEG-LCVDIPG 5946
FT+L + + N LQ T LFKDCS+ G HP AP+ L+VD K+K G L V +
Sbjct 5968 FTTLTLDKINNPRLQC--TTNLFKDCSRSYVGYHPAHAPSFLAVDDKYKVGGDLAVCLNV 6025
Query 5947 IPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTN 6006
+TY RLIS+MGFK++ ++GY +FITR+EAI+ VRAW+GFD EG HA RD++GTN
Sbjct 6026 ADSAVTYSRLISLMGFKLDLTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHAIRDSIGTN 6085
Query 6007 LPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRI 6066
PLQLGFSTG++ V TG + F + A+ PPG+QFKHLIPLM +G W+VVRI
Sbjct 6086 FPLQLGFSTGIDFVVEATGMFAERDGYVFKKAAARAPPGEQFKHLIPLMSRGQKWDVVRI 6145
Query 6067 KIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTY 6126
+IVQMLSD L L+D VV V WA FELT ++YF K+G E C +C KRATCF++ + Y
Sbjct 6146 RIVQMLSDHLVDLADSVVLVTWAASFELTCLRYFAKVGREVVCSVCTKRATCFNSRTGYY 6205
Query 6127 ACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHE 6186
CW HS DY+YNP ++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+
Sbjct 6206 GCWRHSYSCDYLYNPLIVDIQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHD 6265
Query 6187 CFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQA 6246
CF K V+W++EYPII +E+ VN++CR +Q ++ ++A+L +++ V +DIGNPK + CV
Sbjct 6266 CFCKSVNWNLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKG- 6324
Query 6247 EVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTR 6306
++KFYDA P +++ Y Y H D+F DG+C+FWNCNVD+YPANA+VCRFDTR
Sbjct 6325 -YDFKFYDASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTR 6380
Query 6307 VLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDID 6366
VL+ LNLPGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC +D
Sbjct 6381 VLNKLNLPGCNGGSLYVNKHAFHTSPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVD 6440
Query 6367 YVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFT 6426
YVPL+SATCITRCNLGGAVC HA EYR+YL++YN +AGF+ W+YK FD YNLWNTFT
Sbjct 6441 YVPLRSATCITRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFT 6500
Query 6427 RLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFEL 6486
RLQSLENV YN+VN GHFDG AGE P ++I V K+ DV +F+N T P NVA EL
Sbjct 6501 RLQSLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVEL 6560
Query 6487 WAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACS 6546
+AKR+I+P PE+K+ NL +D+ + V+WDY +++ ST VC TD+
Sbjct 6561 FAKRSIRPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYTDL------QCIE 6614
Query 6547 SLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTL--IGES-VKT 6603
SL VLFDGR G ++ F+ RNGV I +K L+ KGP +A +NGV + +G+S V+
Sbjct 6615 SLNVLFDGRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEF 6674
Query 6604 QFNYFKKVDGII-----------QQLPE--------------------TYFTQSRDLEDF 6632
F K D +I + P+ T FTQSR L F
Sbjct 6675 WFAVRKDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRLLSSF 6734
Query 6633 KPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPL 6692
PRS+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHL+IGLA+R Q S L
Sbjct 6735 TPRSEMEKDFMDLDDDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRQQKSNL 6794
Query 6693 KLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTID 6752
+++F+ DS++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS +L +SKVV V +D
Sbjct 6795 VIQEFVTYDSSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVD 6854
Query 6753 YAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIP 6812
+ + FMLWC + V TFYP+LQA+ W+PG MP LYK LE+ +L NYG+ +P
Sbjct 6855 FKDFQFMLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPLERVNLWNYGKPITLP 6914
Query 6813 KGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVD 6872
G MMNVAKYTQLCQYL+T TLAVP NMRV+H GAGSDKGVAPG+AVLRQWLP G++LVD
Sbjct 6915 TGCMMNVAKYTQLCQYLSTTTLAVPANMRVLHLGAGSDKGVAPGSAVLRQWLPAGSILVD 6974
Query 6873 SDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFI 6932
+D+N FVSD+ ++ G+C T+ +WDLIISDMYDP TK++ + N SK+GFFTYLC I
Sbjct 6975 NDVNPFVSDSVASYYGNCITLPFDCQWDLIISDMYDPLTKNIGEYNVSKDGFFTYLCHLI 7034
Query 6933 KQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKE 6992
+ KLALGGS+A+KITE SWNA+LY LMG F++WT F TNVNASSSE FLIG N+L K +
Sbjct 7035 RDKLALGGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNKTRT 7094
Query 6993 QIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEK 7052
+IDG TMHANY+FWRN+ +YSLFDMSKFPLK GTAV+SLK +QIND++ SL+EK
Sbjct 7095 EIDGKTMHANYLFWRNSTMWNGGAYSLFDMSKFPLKAAGTAVVSLKPDQINDLVLSLIEK 7154
Query 7053 GRLIIRENNRVVVSSDILVN 7072
G+L++R+ + V D LVN
Sbjct 7155 GKLLVRDTRKEVFVGDSLVN 7174
Score = 82.8 bits (203), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 52/149 (35%), Positives = 77/149 (52%), Gaps = 2/149 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV D++K + N VIVN AN + HG GVAGA+ + A KE+ D +K
Sbjct 1320 ITPNVCFVKGDVIKVVRLVNAEVIVNPANGRMAHGAGVAGAIAEKAGSAFIKETSDMVKA 1379
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G VG +G L KK L++VGP+ + + LL+ AY++ N D ++ L+SA
Sbjct 1380 QGVCQVGECYESAGGKLCKKVLNIVGPDARGHGKQCYSLLERAYQHINKCDNVVTTLISA 1439
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDK 1158
GIF SL + V V + N++
Sbjct 1440 GIFSVPTDVSLTYLLGVVTKNVILVSNNQ 1468
Score = 79.3 bits (194), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 111/455 (24%), Positives = 194/455 (43%), Gaps = 66/455 (15%)
Query 569 ILDGISEQSLRLVDA-------MVYTSDLLTNSVIIMAYVTGGLVQQTSQWLSNLLGTT- 620
+LDG+ +S L+ + MV S +T+ + MA + V+ ++++ + G
Sbjct 576 LLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMALLFMHDVKVATKYVKKVTGKLA 635
Query 621 -------VEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
V +R I EW + L+ + W + L+ G+F + G I + + +
Sbjct 636 VRFKALGVAVVRKITEWFD--LAVDIAASAAGWLCYQ-LVNGLFAVANGVITFVQE-VPE 691
Query 674 CVKCFIDVVNKALEMCIDQVTIA---GAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLL 730
VK F+D ++ ID ++++ G + V +A SK +Y + K +
Sbjct 692 LVKNFVDKFKAFFKVLIDSMSVSILSGLTVVKTASNRVCLAGSK-VYE--VVQKSLSAYV 748
Query 731 MPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGEL--EALETPVDSFTNGAIVGTPVCVNGL 788
MP+ E T L G+ V + V + L + P SF IV + L
Sbjct 749 MPVGC-SEATCLVGEIEPAVFEDDVVDVVKAPLTYQGCCKPPTSFEKICIV------DKL 801
Query 789 MLLEIKDKEQYCAL---SPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGYKNVRITF 844
+ + D+ + + G+L F G K V F + V ++ + ++ITF
Sbjct 802 YMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAG----KKVEFNDKPKVRKIPSTRKIKITF 857
Query 845 ELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD---LLTNMGIDLDEW 901
LD D VL++ CS + V+ + E VV +AV TL P + + T + LD
Sbjct 858 ALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEHDVIGTKVCALLDRL 917
Query 902 SVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLP 961
+ YLFD+ G+E + RMYCSF PD+E +C ++ + E++ +DD
Sbjct 918 AGDYVYLFDEGGDEVIAPRMYCSFSAPDDE-----DCVAADVVDADENQ---DDD----- 964
Query 962 LEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPE 996
A V V + +EE D + ++E + E
Sbjct 965 ----AEDSAVLVADTQEE----DGVAKGQVEADSE 991
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 5356 bits (13895), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2760/5665 (49%), Positives = 3668/5665 (65%), Gaps = 205/5665 (4%)
Query 1529 SLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHV 1588
S+ ++++LL+ + V TVD N + V +G+ G + DG +VTK++
Sbjct 1598 SVSQIRALLA----NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSA 1653
Query 1589 NHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWAD 1648
H+GK FF A + DE L +Y S L K W G + K ++
Sbjct 1654 IHKGKVFFQYSGLSAADLAAVKDAFGFDEPQLLQYYSMLGMCK-WPVVVCGNYFAFKQSN 1712
Query 1649 NNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRET 1708
NNCY++ L LQ L +KF + R+G F +L+LA + E D +
Sbjct 1713 NNCYINVACLMLQHLSLKFPKWQWRRPGNEFRSGKPLRFVSLVLAKGSFKFNEPSDSTDF 1772
Query 1709 MTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGR 1768
+ L+ A+L A L +CK CG K GV+AVM+ GTL L G +I C CG
Sbjct 1773 IRVELREADLSGATCDLEFICK-CGVKQEQRKGVDAVMHFGTLDKSGLVKGYNIACTCG- 1830
Query 1769 DATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGA 1828
D + Q F++ S P KL + AN +TG GHYTH+ K D
Sbjct 1831 DKLVHCTQFNVPFLICSNTPEGKKLPDDV-VAANIFTGG-SVGHYTHVKCKPKYQLYDAC 1888
Query 1829 HLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQ 1887
+++K+SE KG TD Y K T + +Y LD V +P L YY + YYT+
Sbjct 1889 NVSKVSEAKGNFTDCLYLKNLKQTFSSVLTTYYLDDVKCVAYKPDLSQYYCESGKYYTKP 1948
Query 1888 PIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVV 1945
I T + NFKL A+ LN GF E +T +P GDVV
Sbjct 1949 IIKAQFRTFEKVEGVYTNFKLV--GHDIAEKLNAKLGFDCNSPFMEYKITEWPTATGDVV 2006
Query 1946 AIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF----KPNTWCLRCLWSTKPVDTSNS 2001
Y + + G KP++W ++ + + +P+ C ++ PVD S
Sbjct 2007 LASDDLYVSRYSGGCVTFGKPVIWRGHEEASLKSLTYFNRPSVVCEN-KFNVLPVDVSEP 2065
Query 2002 FE--------------------VLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIEC 2041
+ ++ E + AC S + V+E QK+
Sbjct 2066 TDRRPVPSAVLVTGAASGADASAISTEPGTAKEQKACASDSVEDQIVME---AQKKSSVT 2122
Query 2042 DVKTTEVVGNVILKP-----------SDEGVKVTQELGHEDLMAAYVENTSITIKKPNEL 2090
V EV N + KP KV + L D+ ++ + NEL
Sbjct 2123 TVAVKEVKLNGVKKPVKWNCSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWTANEL 2182
Query 2091 SLALGLKTIATHGIAAINSVPW--SKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPY 2148
S + T+ + V W SK++ L + K + + Y
Sbjct 2183 SRLINSPTVREY-------VKWGMSKLIIPANLLLLRDEKQEFVAPKVVKAKAIACYGAV 2235
Query 2149 VFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFS----KLF 2204
+ LL+ +T++++ + T +A K KLC A N +++ +S F
Sbjct 2236 KWFLLYCFSWIKFNTDNKVIYT--TEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFF 2290
Query 2205 TIA-MWLLLLSICLGSLIC--------------VTAAFGVLLSNFGAPSYCN--GVRELY 2247
+A ++LL + ++I V + + FG + C+ V +L
Sbjct 2291 LVATVFLLWFNFLYANVILSDFYLPNIGPLPMFVGQIVAWVKTTFGVLTICDFYQVTDLG 2350
Query 2248 LNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQ-VTISSYKLD-LTILGLAAEWV 2305
SS FC GS C +C SG D LD+Y ++ +Q V D +++ L E V
Sbjct 2351 YRSS------FCNGSMVCELCFSGFDMLDNYESINVVQHVVDRRVSFDYISLFKLVVELV 2404
Query 2306 LAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIF 2363
+ Y L+T FY L + MQ+ + F+ + W + + M P ++R YI
Sbjct 2405 IGYSLYTVCFYPLFVLVGMQLLTTWLPEFFMLGTMHWSARLFVFVANMLPAFTLLRFYIV 2464
Query 2364 FASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCK 2423
+ Y ++ H+M GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC
Sbjct 2465 VTAMYKVYCLCRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCT 2524
Query 2424 THNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFD 2483
H WNCLNC+++ G+TFI+ E A DLS + KRP+NPTD + Y V V ++ L+++
Sbjct 2525 KHQWNCLNCNSWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVIEVKQVGCSMRLFYE 2584
Query 2484 KAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMC 2543
+ GQ+ Y+ S FV+++ L + KG +V+V + ++ D++ +A+V+Y+Q +
Sbjct 2585 RDGQRVYDDVSASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLY 2642
Query 2544 QPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVAL 2603
+P+L++++ L++ VS MFD YV + V + L + V AH+ L +GV L
Sbjct 2643 RPMLMVEKKLITTANTGLSVSRTMFDLYVYSLLRHLDVDRKSLTSFVNAAHNSLKEGVQL 2702
Query 2604 DGVLSTFVSAARQG-VVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTP 2662
+ V+ TFV AR+ +D+DV+TK + + + + ++ +EVT +SCNN + TY K + +
Sbjct 2703 EQVMDTFVGCARRKCAIDSDVETKSITKSVMAAVNAGVEVTDESCNNLVPTYVKSDTIVA 2762
Query 2663 RDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCA 2722
DLG I NA+H+ + VAK+ NV+ IW+V + LS L+ ++R A K + +LT
Sbjct 2763 ADLGVLIQNNAKHVQSNVAKAANVACIWSVDAFNQLSADLQHRLRKACVKTGLKIKLTYN 2822
Query 2723 TTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNE 2782
V ++TT SLKGG + S + + A L+C + V + +MP + + D
Sbjct 2823 KQEANVPILTTPFSLKGGAVFSRVLQWLFVANLICFI---VLWALMPTYAVHKSDMQLPL 2879
Query 2783 IIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREIG 2840
+K I +GV RD+ TD CFANK FD W+ G Y+N K+CPVV A+I ++IG
Sbjct 2880 YASFKVIDNGVLRDVSVTDACFANKFNQFDQWYESTFGLVYYRNSKACPVVVAVIDQDIG 2939
Query 2841 FIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFK 2900
+ +P VLR LHF+ F+ CYTP I Y +F S CVL++ CT+
Sbjct 2940 HTLFNVPTKVLR-YGFHVLHFITHAFATDRVQCYTPHMQIPYDNFYASGCVLSSLCTMLA 2998
Query 2901 DAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAE 2959
A G P PYCY ++ + YS L P RY L + I+FP EG VRVV T
Sbjct 2999 HADGTPHPYCYTEGVMHNASLYSSLVPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMT 3058
Query 2960 YCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALD 3019
YCR G CE +E GIC + + WVLNN +YRA+ G FCG +A +LI + LVQP+
Sbjct 3059 YCRVGLCEEAEEGICFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVQPIDFFA 3118
Query 3020 VSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLP 3079
++AS VAG I+AI+V A YY +K +R FG+Y VV N +++ ++F +L + Y L
Sbjct 3119 LTASSVAGAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLS 3178
Query 3080 GVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLR 3139
+Y+ FY Y T YF +++S + HLQW M+ I+P W YV + H W F+ Y R
Sbjct 3179 CLYACFYFYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCITYVAVVVSNHALWLFS-YCR 3237
Query 3140 KRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALD 3199
K + + + TFEE AL TF++ KE Y KL++ + +NRYL+LYNKY+YFSG +D
Sbjct 3238 K-IGTDVRSDGTFEEMALTTFMITKESYCKLKNS--VSDVAFNRYLSLYNKYRYFSGKMD 3294
Query 3200 TTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMV 3258
T +YREAAC LAKA+ F+ N+G DVLYQPP S+T++ LQSG KM P+ KVE C+V
Sbjct 3295 TATYREAACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCVV 3354
Query 3259 QVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVI 3318
VT G TLNGLWLDD VYCPRHVIC++ DM +P+Y +LL R ++ F V + + L V+
Sbjct 3355 SVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSDRMSLTVM 3414
Query 3319 GHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKG 3378
+ MQ LL L V NP TPKY F ++PG+TF+VLA YNG P G + MR +HTIKG
Sbjct 3415 SYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVVMRSSHTIKG 3474
Query 3379 SFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDT 3438
SFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q Q D
Sbjct 3475 SFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDY 3534
Query 3439 TITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTG 3498
T T+NV+AWLYAA++N WF+ + +L +FN+ AM + + D V L L++ TG
Sbjct 3535 TQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTG 3592
Query 3499 IAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHH 3558
+ V + AA+K L +G G+ ILGS +LEDE TP DV +Q +GV Q K +++KGT
Sbjct 3593 VTVEQVLAAIKRL-HSGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVIKGTCC 3651
Query 3559 WMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLL 3618
W+L + I+ +W++F +V + L TL + AMLL+KHKH +L ++++
Sbjct 3652 WILASTFLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVIFAMLLIKHKHLYLTMYIM 3710
Query 3619 PSLATVAYFNMVYMPASWVMRIMT--WLELADTSLSGYRLKDCVMYASAL-VLLILMTAR 3675
P L T+ Y N + + R + WL ++ Y D V+Y L V ++ +T R
Sbjct 3711 PVLCTLFYTNYLVVGYKQSFRGLAYAWLSYFVPAVD-YTYMDEVLYGVVLLVAMVFVTMR 3769
Query 3676 TVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAI 3735
++ D ++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA A
Sbjct 3770 SINHDVFSTMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAK 3825
Query 3736 VFVCVEYYPLLFITG-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVST 3794
V +L+ T ++ ++L Y +GY CCCY+G+ LLN FR+ LGVY+Y +S
Sbjct 3826 VIAKWLAVNVLYFTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISV 3885
Query 3795 QEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQ 3854
QE RYMN+ GL PP++S +A LN KLLGIGG P I+V+ +QS+++DVKC +VVLL+ LQ
Sbjct 3886 QELRYMNANGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQ 3945
Query 3855 QLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLC 3908
L + S+SKLW C LHN+IL D + AF+K+ LL VL + AVD I +
Sbjct 3946 HLHIASNSKLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVS 4005
Query 3909 EEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSE 3967
++ + + LQA+ SEF ++ S+ Y A++ ++A A+G + + +K+L+K+ N+AKS
Sbjct 4006 DDYVRDNTVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSA 4065
Query 3968 FDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIIN 4027
++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++
Sbjct 4066 YERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILD 4125
Query 4028 NARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQ 4087
NA GCVPLN IP T+ L ++VPD + D TYA +W IQ + DAD + Q
Sbjct 4126 NAVKGCVPLNAIPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQ 4185
Query 4088 LSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNA 4145
L+EI+++++ WPL+++A R N S V LQNNEL P LR +G+ +
Sbjct 4186 LNEIDVNST----WPLVISANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNC--NIPT 4239
Query 4146 LAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL 4205
YYN + G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYL
Sbjct 4240 QCYYNTTGTGKIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYL 4298
Query 4206 YFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGG 4265
YF+KG N L RG V+G+L++TVRLQAG ATE +NS +LS CAF+VDP K Y DY+ GG
Sbjct 4299 YFVKGCNTLARGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIQQGG 4358
Query 4266 QPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGK 4325
P+TNCVKMLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK
Sbjct 4359 VPVTNCVKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGK 4418
Query 4326 YVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSA 4385
+VQ+P DPV + L + VC VCG W+ CSC QS D + FLNRV G S
Sbjct 4419 FVQVPLG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVGTGSQF-QSKD-TNFLNRVRGTSV 4475
Query 4386 -ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRH 4444
ARL PC +G TDV RAFDI N AG + K NC RFQ DEEGN LD +FVVKR
Sbjct 4476 NARLVPCASGLDTDVQLRAFDICNANRAGIGLYYKVNCFRFQRVDEEGNKLDKFFVVKRT 4535
Query 4445 TMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFD 4504
+ Y E+ Y L KDC VA H+FF F V+G VPHI R+ L+K+TM DL YALRHFD
Sbjct 4536 NLEVYNKEKECYELTKDCGVVAEHEFFTFDVEGSRVPHIVRKDLSKFTMLDLCYALRHFD 4595
Query 4505 EGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDA 4564
+C TLKEIL+TY CD+ YF KKDWYDFVENPDI+ VY LG ++LL T F D
Sbjct 4596 RNDCSTLKEILLTYAECDESYFQKKDWYDFVENPDIINVYKKLGPIFNRALLNTANFADT 4655
Query 4565 MRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAES 4624
+ +AG+VGVLTLDNQDL G WYDFGDFV+ P CGV + DSYYS +MP+LT+ AL +E
Sbjct 4656 LVEAGLVGVLTLDNQDLYGQWYDFGDFVKTVPCCGVAVADSYYSYMMPMLTMCHALDSEL 4715
Query 4625 HMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNV 4684
++ + +DL++YDFT+ +L LF++YFK+W TYHPN C DDRCI+HCANFN+
Sbjct 4716 FVNGTYRE----FDLVQYDFTDFKLELFNKYFKHWSMTYHPNTSECEDDRCIIHCANFNI 4771
Query 4685 LFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYA 4744
LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YA
Sbjct 4772 LFSMVLPKTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYA 4831
Query 4745 ADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSV 4804
ADPA+H AS + LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV
Sbjct 4832 ADPALHVASASALLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSV 4891
Query 4805 ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIV 4864
+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFVVEVV+KYF+ Y+GGCI A QVIV
Sbjct 4892 DLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVVEVVNKYFEIYEGGCIPATQVIV 4951
Query 4865 NNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRAR 4924
NN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRAR
Sbjct 4952 NNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRAR 5011
Query 4925 TVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLM 4984
TVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LM
Sbjct 5012 TVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLM 5071
Query 4985 GWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYV 5044
GWDYPKCDRAMPN+LRI++SLVLARKH++CC+ + RFYRLANECAQVL E+VMCGG YV
Sbjct 5072 GWDYPKCDRAMPNILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLGEIVMCGGCYYV 5131
Query 5045 KPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNR 5104
KPGGTSSGDATTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR
Sbjct 5132 KPGGTSSGDATTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRAD 5191
Query 5105 DVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMS 5164
VD FV E+Y +L KHFSM+ILSDD VVCYNS +A++G +A+I +F+ VLYYQNNVFMS
Sbjct 5192 HVDPAFVSEYYEFLNKHFSMIILSDDGVVCYNSEFASKGYIANISDFQQVLYYQNNVFMS 5251
Query 5165 EAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLM 5224
EAKCW ETD+ KGPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+
Sbjct 5252 EAKCWVETDIEKGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLL 5311
Query 5225 IERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRY 5284
IERFVSLAIDAYPL H N EY +VF +YL+YI+KL+++L +LD SV+L+ + ++
Sbjct 5312 IERFVSLAIDAYPLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSISVILSTCDGQKF 5371
Query 5285 WEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVL 5344
+ FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VL
Sbjct 5372 TDETFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVL 5431
Query 5345 SVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNV 5404
SV+PYVCN+PGCDV DVT+LYLGGMSYYC++HKP SF L NG VFGLYK +C GS +
Sbjct 5432 SVSPYVCNSPGCDVNDVTKLYLGGMSYYCEAHKPQYSFKLVMNGMVFGLYKQSCTGSPYI 5491
Query 5405 TDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDREL 5464
DFN IA+C WT DY+LAN CTERLKLFAAET KATEE FK Y AT+RE++SDREL
Sbjct 5492 EDFNKIASCKWTEVDDYVLANECTERLKLFAAETQKATEEAFKQCYASATIREIVSDREL 5551
Query 5465 HLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGD 5524
LSWE+GK RPPLN+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD
Sbjct 5552 ILSWEIGKVRPPLNKNYVFTGYHFTNNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGD 5611
Query 5525 YFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQ 5582
F+LTSH V LSAPTLVPQE+Y VR Y ++ + F +NV NYQ +G+++Y T+Q
Sbjct 5612 VFILTSHAVSSLSAPTLVPQENYTSVRFASAY---SVPETFQNNVPNYQHIGIKRYCTVQ 5668
Query 5583 GPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVE 5642
GPPGTGKSH AIG A+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+
Sbjct 5669 GPPGTGKSHLAIGHAVYYCTARVVYTAASHAAVDALCEKAHKFLNINDCARIVPAKLRVD 5728
Query 5643 CFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGD 5702
C+DKF VN T +YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGD
Sbjct 5729 CYDKFNVNDTTRKYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGD 5788
Query 5703 PAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKL 5762
PAQLPAPR LL KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY+NKL
Sbjct 5789 PAQLPAPRVLLNKGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYNNKL 5848
Query 5763 KAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAV 5822
KA D SA CFK++YKG TH+ SSA+N QI ++ + L NP+W AVFISPYNSQN V
Sbjct 5849 KAKNDNSAMCFKVYYKGQTTHESSSAVNMQQIHLISKLLKANPSWSNAVFISPYNSQNYV 5908
Query 5823 ASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDL 5882
A ++LGL TQT DS+QGS YD+VI++QT +TAHS NVNRFNVAITRAK GILC+MS L
Sbjct 5909 AKRVLGLQTQTADSAQGSAYDFVIYSQTAQTAHSVNVNRFNVAITRAKKGILCVMSSMQL 5968
Query 5883 YDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEG-LC 5941
FT+L + + N LQ T LFKDCSK G+ P L+VD K+K G L
Sbjct 5969 IGVFNFTTLTLDKINNPRLQC--TTNLFKDCSKSYVGIPP--CAFLLAVDDKYKVSGNLA 6024
Query 5942 VDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRD 6001
V + +TY RLIS+MGFK++ ++GY +FITR+EAI+ VRAW+GFD EG HATRD
Sbjct 6025 VCLNVADSAVTYSRLISLMGFKLDLTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHATRD 6084
Query 6002 AVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPW 6061
++GTN PLQLGFSTG++ V TG + F + A+ PPG+QFKHL+PLM +G W
Sbjct 6085 SIGTNFPLQLGFSTGIDFVVEATGMFAERDGYVFKKAAARAPPGEQFKHLVPLMSRGQKW 6144
Query 6062 NVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFST 6121
+VVRI+IVQMLSD L L+D VV V WA FELT ++YF K+G E C +C+KRATCF++
Sbjct 6145 DVVRIRIVQMLSDHLVDLADSVVLVTWAASFELTCLRYFAKVGKEVVCSVCNKRATCFNS 6204
Query 6122 SSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRC 6181
+ Y CW HS DY+YNP ++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRC
Sbjct 6205 RTGYYGCWRHSYSCDYLYNPLIVDIQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRC 6264
Query 6182 LAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIK 6241
LAVH+CF K V+W++EYPII +E+ VN++CR +Q ++ ++A+L +++ V +DIGNPK +
Sbjct 6265 LAVHDCFCKSVNWNLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLA 6324
Query 6242 CVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVC 6301
CV ++KFYDA P +++ Y Y H D+F DG+C+FWNCNVD+YPANA+VC
Sbjct 6325 CVKG--YDFKFYDASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVC 6379
Query 6302 RFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQV 6361
RFDTRVLS LNLPGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC
Sbjct 6380 RFDTRVLSKLNLPGCNGGSLYVNKHAFHTNPFTRAAFENLKPMPFFYYSDTPCVYMEGME 6439
Query 6362 VSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNL 6421
+DYVPL+SATCITRCNLGGAVC HA EYR+YL++YN +AGF+ W+YK FD YNL
Sbjct 6440 SKQVDYVPLRSATCITRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNL 6499
Query 6422 WNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVN 6481
WNTFTRLQSLENV YN+VN GHFDG AGE P ++I V K+ DV +F+N T P N
Sbjct 6500 WNTFTRLQSLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTN 6559
Query 6482 VAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPT 6541
VA EL+A+R+I+P PE+K+ + + + N V+WDY +++ ST VC TD+
Sbjct 6560 VAVELFAERSIRPHPELKLFRSSNIHVCWNHVLWDYAKDSVFCSSTYKVCKYTDL----- 6614
Query 6542 ESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTL--IGE 6599
SL VLFDGR G ++ F+ RNGV I +K L+ KGP +A +NGV + +G+
Sbjct 6615 -QCIESLNVLFDGRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGD 6673
Query 6600 S-VKTQFNYFKKVDGII-----------QQLPE--------------------TYFTQSR 6627
S V+ F + D +I + P+ T FTQSR
Sbjct 6674 SDVEFWFAMRRDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSR 6733
Query 6628 DLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRS 6687
L F PRS+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHL+IGLA+R
Sbjct 6734 FLSSFSPRSEMEKDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRP 6793
Query 6688 QDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVV 6747
+ S L +++F+P DS++ +YFITD +GSS+ VC+VIDLLLDDFV+I+KS +L +SKVV
Sbjct 6794 KKSNLVIQEFVPYDSSIHSYFITDENSGSSESVCTVIDLLLDDFVDIVKSLNLKCVSKVV 6853
Query 6748 KVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGE 6807
V +D+ + FMLWC + V TFYP+LQA+ W+PG MP LYK +E+ +L NYG+
Sbjct 6854 NVNVDFKDFQFMLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPMERVNLWNYGK 6913
Query 6808 NAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTG 6867
+P G MMNVAKYTQLCQYL+T TLAVP NMRV+H GAGSDKGVAPG+AVLRQWLP+G
Sbjct 6914 PITLPTGCMMNVAKYTQLCQYLSTTTLAVPANMRVLHLGAGSDKGVAPGSAVLRQWLPSG 6973
Query 6868 TLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTY 6927
++LVD+D+N FVSD+ ++ G+C T+ +WDLIISDMYDP TK++ + N SK+GFFTY
Sbjct 6974 SILVDNDMNPFVSDSVASYYGNCITLPFDCQWDLIISDMYDPLTKNIGEYNVSKDGFFTY 7033
Query 6928 LCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYL 6987
LC I+ KLALGGS+A+KITE SWNA+LY LMG F++WT F TNVNASSSE FLIG N+L
Sbjct 7034 LCHLIRDKLALGGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWL 7093
Query 6988 GKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIY 7047
+ + +IDG TMHANY+FWRN+ +YSLFDM+KFPLK GTAV+SLK +QIND++
Sbjct 7094 NRTRNEIDGKTMHANYLFWRNSTMWNGGAYSLFDMTKFPLKAAGTAVVSLKPDQINDLVL 7153
Query 7048 SLLEKGRLIIRENNRVVVSSDILVN 7072
SL+EKG+L++R+ + V D LVN
Sbjct 7154 SLIEKGKLLVRDTRKEVFVGDSLVN 7178
Score = 75.9 bits (185), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 98/390 (25%), Positives = 165/390 (42%), Gaps = 45/390 (12%)
Query 569 ILDGISEQSLRLVDA-------MVYTSDLLTNSVIIMAYVTGGLVQQTSQWLSNLLGTTV 621
+LDG+ +S L+ + MV S + + + MA + V+ ++++ + G
Sbjct 576 LLDGLVPRSYYLIKSGQAFTSLMVNFSREVVDMCMDMALLFMHDVKVATKYVKKVTGKVA 635
Query 622 EK--------LRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
+ +R I EW + + W + L+ G+F + G I + + +
Sbjct 636 VRFKALGIAVVRKITEWFDLAVDTAAS--AAGWLCYQ-LVNGLFAVANGVITFIQE-VPE 691
Query 674 CVKCFIDVVNKALEMCIDQVTIA---GAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLL 730
VK F+D ++ ID ++++ G + V +A SK +Y + K +
Sbjct 692 LVKNFVDKFKTFFKVLIDSMSVSILSGLTVVKTASNRVCLAGSK-VYE--VVQKSLPAYI 748
Query 731 MPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGEL--EALETPVDSFTNGAIVGTPVCVNGL 788
MP+ E T L G+ V + V + L + P SF IV + L
Sbjct 749 MPVGC-SEATCLVGEIEPAVFEDDVVDVVKAPLTYQGCCKPPSSFEKICIV------DKL 801
Query 789 MLLEIKDKEQYCAL---SPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGYKNVRITF 844
+ + D+ + + G+L F G K V F + V EV + ++I F
Sbjct 802 YMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAG----KKVVFNDKPKVKEVPSTRKIKIIF 857
Query 845 ELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD---LLTNMGIDLDEW 901
LD D VL++ CS + V+ + E VV +AV TL P + + T + L+
Sbjct 858 ALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEHGVIGTKVCALLERL 917
Query 902 SVATFYLFDDAGEENFSSRMYCSFYPPDEE 931
YLFD+ GEE +SRMYCSF PDE+
Sbjct 918 VDDYVYLFDEGGEEVIASRMYCSFSAPDED 947
Score = 60.1 bits (144), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 54/149 (36%), Positives = 77/149 (52%), Gaps = 2/149 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV D++K + VIVN AN + HG GVAGA+ KA A E+ D +K
Sbjct 1319 ITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKAFINETADMVKA 1378
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G VGG +G L KK L++VGP+ + E LL+ AY++ N D ++ L+SA
Sbjct 1379 QGVCQVGGCYESTGGKLCKKVLNIVGPDARGHGNECYSLLERAYQHINKCDNVVTTLISA 1438
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDK 1158
GIF SL + V V + N++
Sbjct 1439 GIFSVPTDVSLTYLLGVVTKNVILVSNNQ 1467
Score = 41.6 bits (96), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 50/202 (25%), Positives = 82/202 (41%), Gaps = 21/202 (10%)
Query 1573 PTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSE-AFEYYHTLDESFLGRYMSALNHTK 1631
P ++ D+ K++ + E +T P+D T AF+ ++ S S H K
Sbjct 1047 PDQVEAFDIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPSDETHFK 1106
Query 1632 KWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALI 1691
V G S NC+L S L+ +Q L ++F +Q+ + +AG F +
Sbjct 1107 ------VCGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKL 1160
Query 1692 LAYSNKTV--GELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMG 1749
+ + K++ + G V + L S K N C CG + L G++AV + G
Sbjct 1161 VKSAPKSIILPQGGYVADFAYFFLSQC---SFKVHANWRCLKCGME-LKLQGLDAVFFYG 1216
Query 1750 TLSYDNLKTGVSIPCVCGRDAT 1771
+ VS C CG T
Sbjct 1217 DV--------VSHMCKCGNSMT 1230
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 5319 bits (13797), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2727/5615 (49%), Positives = 3646/5615 (65%), Gaps = 169/5615 (3%)
Query 1543 KTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
K I V TVD N + + + +G+ G + DG DVTK+K + K + +
Sbjct 1620 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1679
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ 1662
A + D+ L Y + L KW G S + + NNCY++ L LQ
Sbjct 1680 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1738
Query 1663 LEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAK 1722
+ +KFN QEA+Y RAG AL+LA + E D + + +L+ A+L A
Sbjct 1739 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1798
Query 1723 RVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVC-GRDATQYLVQQESSF 1781
L ++C CG K + GV+AVM+ GTL+ +L G I C C GR + + F
Sbjct 1799 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGR--IVHCTKLNVPF 1855
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S P L + AN + G GHYTH+ D + K + G +T
Sbjct 1856 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1913
Query 1842 DVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLP-- 1898
D Y K + T T +Y LD V P L YY + YYT +PI +P
Sbjct 1914 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKV 1972
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGFTKPAS-RELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL + LN GF E VT +P GDVV Y +
Sbjct 1973 DGVYTNFKLVGHD--ICAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYF 2030
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKP-VDTSNSFEVLAVEDTQGMDNL 2016
KG + KP++W + + + + KP + N + VL+V D++
Sbjct 2031 KGCETFGKPVIWLCHDEASLNSLT---------YFNKPSFKSENRYSVLSV------DSV 2075
Query 2017 ACESQQPTSEEVVENPTIQKEV-IECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
+ ESQ V+E+ KEV ++ KT ++ +I+ + +KV + L D+
Sbjct 2076 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2135
Query 2076 YVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAK 2135
Y+ + NELS + T+ + I + L ++ Q +
Sbjct 2136 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPITIPIDLLCLRD-DNQTLLVPKIFKA 2194
Query 2136 RLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYV 2195
R + F ++ ++F +F L FT T IA ++ L L
Sbjct 2195 RAIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAFQTF 2248
Query 2196 KSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGV----------------LLSNFGAPSY 2239
+ F K F + + L + + + F + + + FG +
Sbjct 2249 RWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTI 2308
Query 2240 CNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL--DLTI 2297
C+ +L + T FC GSF C +C SG D LD+Y A++ +Q + L +++
Sbjct 2309 CDFYSKLGVG----FTSHFCNGSFICELCYSGFDMLDTYAAIDFVQYEVDRRVLFDYVSL 2364
Query 2298 LGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVS 2355
+ L E V+ Y L+T +FY L +Q+F + F+ + WL+ FI+ + M P
Sbjct 2365 VKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAF 2424
Query 2356 AMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYA 2415
++R YI + Y + HI+ GC + C+ CYKRN + RV+C+TIV G+ R + + A
Sbjct 2425 VLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITA 2484
Query 2416 NGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKN 2475
NGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2485 NGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVG 2544
Query 2476 GALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSAS 2535
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + S D + +A
Sbjct 2545 CMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVE--SDADRANFLNAV 2602
Query 2536 VYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHS 2595
V+Y+Q + +PILL+D+ L++ + V+ MFD YVDTF + F V + V AH+
Sbjct 2603 VFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVNIAHA 2662
Query 2596 ELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTY 2654
L +GV L+ VL TFV R+ +D+DV+T+ + + + + + LE T ++ NN + TY
Sbjct 2663 SLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVPTY 2722
Query 2655 NKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNN 2714
K +N+ DLG I A+H+ VAK+ N+S IW + + L+ L+ +++ A K
Sbjct 2723 LKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDTFNQLTADLQHKLKKACVKTG 2782
Query 2715 IPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLS 2774
+ +LT V ++TT SLKGG ++S ++ +L+C + + + ++P +++
Sbjct 2783 LKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPTYSVY 2839
Query 2775 IHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGS--YKNDKSCPVVA 2832
D + +K I +GV RDI D CFANK FD W+ GS Y N CP+V
Sbjct 2840 KSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSFYYHNSMDCPIVV 2899
Query 2833 AIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVL 2892
A++ +IG + +P VLR LHFL F++ CYTP I Y+DF S CVL
Sbjct 2900 AVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVL 2958
Query 2893 AAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVR 2951
++ CT+FK G P PYCY +++ + Y+ L P TRY L + + I+FP+ EG VR
Sbjct 2959 SSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVR 3018
Query 2952 VVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPL 3011
+V T YCR G CE +E GIC + + WVLNN++YR++ G FCG D +L F+ L
Sbjct 3019 IVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQFFSSL 3078
Query 3012 VQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCL 3071
++P+ ++AS + G I+AI+V YY +K +R FG+Y VV N +++ ++F +L +
Sbjct 3079 IRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFV 3138
Query 3072 VPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCH 3131
Y VY+ FY Y+T YF +++S + HLQW M+ I+PFW YV + H
Sbjct 3139 FQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVL 3198
Query 3132 WFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKY 3191
W F+ Y RK + N STFEE +L TF++ K+ Y +L++ + YNRYL+LYNKY
Sbjct 3199 WLFS-YCRK-IGVNVCNDSTFEETSLTTFMITKDSYCRLKNS--VSDVAYNRYLSLYNKY 3254
Query 3192 KYFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPS 3250
+Y+SG +DT +YREAAC LAKA+ F+ N+G DVLYQPP S++++ LQSG KM P+
Sbjct 3255 RYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPT 3314
Query 3251 GKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQA 3310
K+E C+V VT G+ TLNGLWLDD VYCPRHVIC + +M P+Y LL R + F + +
Sbjct 3315 SKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDFTIMS 3374
Query 3311 GNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAM 3370
G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + M
Sbjct 3375 GRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAFHVTM 3434
Query 3371 RPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQT 3430
R ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q
Sbjct 3435 RSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYRDAQV 3494
Query 3431 AQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL 3490
Q D T+NV+AWLYAA++N WF+ ++ DFN+ AM + + D V L
Sbjct 3495 VQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADLV--L 3552
Query 3491 GPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFK 3550
L++ TG+++ + AA+K L G GR ILGS EDE P DV +Q +GV Q K K
Sbjct 3553 DALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTK 3611
Query 3551 KIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKH 3610
+ +K T +W+L++ I+ +W++F ++ + TL ++ + MLLVKHKH
Sbjct 3612 RFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLVKHKH 3670
Query 3611 AFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASAL-VL 3668
+L ++++P L T+ Y N +V + WL +++ + + V Y L V
Sbjct 3671 FYLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYE-VFYGCILCVF 3729
Query 3669 LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTI 3728
I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ T + TTI
Sbjct 3730 AIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLFITAFLGTYTW----TTI 3785
Query 3729 MFLARA-IVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGV 3787
+ LA A IV + F ++ I+L Y F+GY CY+G F LLN FR+ +GV
Sbjct 3786 LSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMGV 3845
Query 3788 YDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSV 3847
Y+Y +S QE RYMN+ GL PP++S +A LN+KLLGIGG P I+V+ +QSK++DVKC +V
Sbjct 3846 YNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCANV 3905
Query 3848 VLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD---- 3903
VLL+ LQ L V S+S+LW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3906 VLLNCLQHLHVASNSRLWQYCSILHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDTKCL 3965
Query 3904 --INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKS 3960
I+ + ++ + + LQA+ SEF ++ S+ Y A++ A +G ++ +K+L+K+
Sbjct 3966 ASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKA 4025
Query 3961 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4020
N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN
Sbjct 4026 CNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQ 4085
Query 4021 ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD 4080
ALN+I++NA GCVPLN IP A L +++PD + D YA ++W IQ V D
Sbjct 4086 ALNSILDNAVKGCVPLNAIPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQTVQD 4145
Query 4081 ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGTTQT 4138
AD QL++I++D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4146 ADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDMN 4201
Query 4139 ACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPK 4198
+ YYNN GR V A+LSD LK+ + K DG + EL+PPC+F K
Sbjct 4202 C--NIPTQCYYNNGSSGRIVYAVLSDVDGLKYTKIIKDDGNCVV-LELDPPCKFSIQDVK 4258
Query 4199 GPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYK 4258
G K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VDP K Y
Sbjct 4259 GLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKTYL 4318
Query 4259 DYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKG 4318
DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+ G
Sbjct 4319 DYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDVDG 4378
Query 4319 FCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D + FLN
Sbjct 4379 LCKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SGVAVQSKDLN-FLN 4435
Query 4379 RVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDS 4437
RV G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D++GN LD
Sbjct 4436 RVRGTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDGNKLDK 4495
Query 4438 YFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLV 4497
+FVVKR + Y E+T Y L K C VA HDFF F +DG VPHI R+ L+KYTM DL
Sbjct 4496 FFVVKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRKNLSKYTMLDLC 4555
Query 4498 YALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLK 4557
YALRHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG ++LL
Sbjct 4556 YALRHFDCNDCSVLCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFNRALLN 4615
Query 4558 TVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLT 4617
TV F D + G+VGVLTLDNQDL G WYDFGDF+Q APG GV + DSYYS +MP+LT+
Sbjct 4616 TVSFADTLVKVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMPMLTMC 4675
Query 4618 RALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCIL 4677
L E ++ + +DL++YDFT+ +L LF++YFKYW YHPN ++C +DRCI+
Sbjct 4676 HVLDCELFVNDSYRQ----FDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDNDRCII 4731
Query 4678 HCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSF 4737
HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS
Sbjct 4732 HCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHRYRLSL 4791
Query 4738 KELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGF 4797
K+LL+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F SKG
Sbjct 4792 KDLLLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFVKSKGL 4851
Query 4798 FKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCI 4857
FKEGS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGGCI
Sbjct 4852 FKEGSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGGCI 4911
Query 4858 NANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAI 4917
A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMNLKYAI
Sbjct 4912 PASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMNLKYAI 4971
Query 4918 SAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSD 4977
SAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + D
Sbjct 4972 SAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRHLIKD 5031
Query 4978 VETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVM 5037
V+ P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ RFYRLANECAQVLSE+VM
Sbjct 5032 VDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVLSEIVM 5091
Query 5038 CGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLY 5097
CGG YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNLQ RLY
Sbjct 5092 CGGCYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNLQKRLY 5151
Query 5098 ECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYY 5157
+YR VD+ FV+E+Y +L KHFSMMILSDD VVCYNS+YA++G +A+I F+ VLYY
Sbjct 5152 SNVYRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYASKGYIANISVFQQVLYY 5211
Query 5158 QNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIV 5217
QNNVFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCFVDD++
Sbjct 5212 QNNVFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCFVDDLL 5271
Query 5218 KTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLT 5277
KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD YSV+L+
Sbjct 5272 KTDSVLLIERFVSLAIDAYPLVHHENEEYQKVFRVYLEYIKKLYNDLGNQILDSYSVILS 5331
Query 5278 NDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVIS 5337
+ ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV++
Sbjct 5332 TCDGLKFTDESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHVMA 5391
Query 5338 TSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNT 5397
T+HK VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFGLYK +
Sbjct 5392 TNHKYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFGLYKQS 5451
Query 5398 CVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVRE 5457
C GS + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY AT++E
Sbjct 5452 CTGSPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYASATIQE 5511
Query 5458 VLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTT 5517
++SDRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V YR TTT
Sbjct 5512 IVSDREIILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYYRATTT 5571
Query 5518 YKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLY--PTLNISDEFSSNVANYQKV 5573
YKL++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y P L F +NVANYQ +
Sbjct 5572 YKLSIGDVFVLTSHSVANLSAPTLVPQENYASIRFSSVYSVPLL-----FQTNVANYQHI 5626
Query 5574 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5633
GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+R
Sbjct 5627 GMKRYCTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNINDCTR 5686
Query 5634 IIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLR 5693
IIPA+ RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NAR++
Sbjct 5687 IIPAKVRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINARVK 5746
Query 5694 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5753
AKHYVYIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV+TV
Sbjct 5747 AKHYVYIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIVETV 5806
Query 5754 SALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5813
SALVYDNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W AVFI
Sbjct 5807 SALVYDNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSAVFI 5866
Query 5814 SPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGI 5873
SPYNSQN VA +ILG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK GI
Sbjct 5867 SPYNSQNYVAKRILGVQTQTVDSAQGSEYDYVIYSQTAETAHSINVNRFNVAITRAKKGI 5926
Query 5874 LCIMSDRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKIITGLHPTQAPTHLSVD 5932
C+MS+ L++ L F +L + + TL + T LFKDCSK G HP AP+ LSVD
Sbjct 5927 FCVMSNMQLFESLNFITLPLDKIQNQTLSRLHCTTNLFKDCSKNFLGYHPAHAPSFLSVD 5986
Query 5933 IKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGF 5991
K+K E L V + +TY RLIS+MGFK++ ++GY FIT++EAI+ VR W+GF
Sbjct 5987 DKYKVNEDLAVCLNICEPVLTYSRLISLMGFKLDLTLDGYSKFFITKDEAIKRVRGWVGF 6046
Query 5992 DVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHL 6051
DVEG HATRD +GTN PLQ+GFSTGV+ V TG + F R AK PPGD FKHL
Sbjct 6047 DVEGAHATRDNIGTNFPLQIGFSTGVDFVVEATGLFAERDCYIFKRTVAKAPPGDNFKHL 6106
Query 6052 IPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCL 6111
IPLM KG W+VVRI+IVQMLSD L LSD VVF+ W+ FELT ++YF K+G E C +
Sbjct 6107 IPLMSKGQKWDVVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELNCDV 6166
Query 6112 CDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHV 6171
C RATC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD C VH AHV
Sbjct 6167 CPNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKGAHV 6226
Query 6172 ASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVL 6231
AS DAIMTRCLA+++CF K V+W++EYPII +E+ +N++CR +Q +++K+A+L +++ +
Sbjct 6227 ASSDAIMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRYNLC 6286
Query 6232 HDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNV 6291
+DIGNPK I CV + E+KFYDA P +++LFY Y H D F DG+C+FWNCNV
Sbjct 6287 YDIGNPKGIACVK--DYEFKFYDASPV---VKSVKQLFYVYDVHKDNFKDGLCMFWNCNV 6341
Query 6292 DRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSD 6351
D+YP+N+IVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFYYSD
Sbjct 6342 DKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFYYSD 6401
Query 6352 SPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLW 6411
+PC +DYVPL+SATCITRCNLGGAVC HA +Y +YL++YN+ +AGF+ W
Sbjct 6402 TPCVYVDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEDYCKYLESYNVATTAGFTFW 6461
Query 6412 IYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEI 6471
+YK FD YNLWNTFT LQSLENV YN+VN GH+DG GE P +I+N+ V K++ +D I
Sbjct 6462 VYKTFDFYNLWNTFTMLQSLENVIYNLVNAGHYDGRIGELPCAIMNDKVVVKINNVDTVI 6521
Query 6472 FENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVC 6531
F+N T+LP N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +++ ST GVC
Sbjct 6522 FKNNTSLPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVC 6581
Query 6532 TMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASV 6591
TD+ + +L VLFDGR G ++ FR ARNGV I+ G + L+ KGP +A +
Sbjct 6582 KYTDL------NFIENLNVLFDGRDNGALEAFRKARNGVFISTGKLSSLSMIKGPQRADL 6635
Query 6592 NGVTL--IGE-SVKTQFNYFKKVDGIIQQLPE---------------------------- 6620
NGV + +GE +V+ F K D +I +
Sbjct 6636 NGVIVDKVGELNVEFWFAMRKDGDDVIFSRADSLSPSHYWSPQGNLGGNCAGNASGNDAL 6695
Query 6621 ---TYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGL 6677
T FTQSR L F+PRS +E DF+++ FI +Y LE YAF+HIVYG F++ +GGL
Sbjct 6696 ARFTIFTQSRVLSTFEPRSDLERDFIDMEDSLFIAKYGLEDYAFDHIVYGSFNYKVIGGL 6755
Query 6678 HLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKS 6737
HL+IGL +R + S L +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS
Sbjct 6756 HLLIGLFRRLKKSNLVIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVVIVKS 6815
Query 6738 QDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLL 6797
+L+ +SKVV + +D+ + FMLWC D + TFYPK+QA+ W+PG +MP LYK + L
Sbjct 6816 LNLNCVSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATSDWKPGYSMPVLYKYLNVPL 6875
Query 6798 EKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGT 6857
E+ L NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+
Sbjct 6876 ERVSLWNYGKAINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEVAPGS 6935
Query 6858 AVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKE 6917
AVLRQWLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TK++
Sbjct 6936 AVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKNIGDY 6995
Query 6918 NDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSS 6977
N SK+GFFTY+C I+ KL+LGGS+A+KITE SWNADLYKLM +F++WT F TNVNASSS
Sbjct 6996 NVSKDGFFTYICYLIRDKLSLGGSVAIKITEFSWNADLYKLMSYFAFWTVFCTNVNASSS 7055
Query 6978 EAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSL 7037
E FLIG NYLGK +IDG MHANY+FWRN+ +YSLFDMSKF LKL GTAV++L
Sbjct 7056 EGFLIGINYLGKSCFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMSKFSLKLAGTAVVNL 7115
Query 7038 KENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
+ +Q+ND++YSL+E+G+L++R+ + + D LVN
Sbjct 7116 RPDQLNDLVYSLIERGKLLVRDTRKEIFVGDSLVN 7150
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 55/157 (35%), Positives = 80/157 (51%), Gaps = 2/157 (1%)
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
L +T NV DI+ A+ VIVN AN H+ HGGGVA A+ A KE+ +
Sbjct 1328 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1387
Query 1070 KLNGPLTVGGSCLLSGHNLAKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQDILLAPLL 1127
K G VG + +G L K L++VGP+ + + LL AY++ N+ D L+ L+
Sbjct 1388 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1447
Query 1128 SAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
SAGIF SL + V QV + N+K ++ +
Sbjct 1448 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDII 1484
Score = 81.3 bits (199), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 90/362 (25%), Positives = 158/362 (44%), Gaps = 48/362 (13%)
Query 616 LLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCV 675
LLGTT+ + + W L A W +L L+ G+F + + + I D
Sbjct 615 LLGTTL--VNKMVNWFNTMLDASAP--ATGW-LLYQLLNGLFVVSQANFNFVA-LIPDYA 668
Query 676 KCFIDVVNKALEMCIDQVTIAGAK----LRSLN-----LGEVFIAQSKGLYRQCIRGKEQ 726
K ++ ++ ++ VT+ K L+++N +G F S GL I G
Sbjct 669 KILVNKFYTFFKLLLECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGL----IPG--- 721
Query 727 LQLLMPLKA-PKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSF---TNGAIVGTP 782
++P A +++ F EG +E V++++ +E +++ + S+ V
Sbjct 722 --FVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEKI 772
Query 783 VCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGG--APIKG--VTFGED-TVWEVQGY 837
++ + + + DK P ++ N+ L P G V F E V E+
Sbjct 773 CIIDNMYMGKCGDK-----FFPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 838 KNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD---LLTNM 894
V++ F+LD D +L + CS + VE G V +F VV +A+ L D + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKDHPVVGYQV 887
Query 895 GIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTE 954
L++ + YLFD+AG+E +SRMYC+F D E+ +E E+ ID E +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 955 DD 956
+D
Sbjct 948 ED 949
Score = 44.3 bits (103), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 38/137 (28%), Positives = 60/137 (44%), Gaps = 14/137 (10%)
Query 1637 QVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSN 1696
+V GL S NC+L SVLL +Q+L KF A++ + + G +F +L
Sbjct 1117 KVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTTIP 1176
Query 1697 KTV--GELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYD 1754
K + + G V + L ++ + N C CG + L G++AV + G +
Sbjct 1177 KAIVLPQGGYVADFAYWFLNQFDINAYA---NWCCLKCG-FSFDLNGLDAVFFYGDI--- 1229
Query 1755 NLKTGVSIPCVCGRDAT 1771
VS C CG + T
Sbjct 1230 -----VSHVCKCGHNMT 1241
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 5317 bits (13792), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2724/5619 (48%), Positives = 3652/5619 (65%), Gaps = 177/5619 (3%)
Query 1543 KTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
K I V TVD N + + + +G+ G + DG DVTK+K + K + +
Sbjct 1600 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1659
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ 1662
A + D+ L Y + L KW G S + + NNCY++ L LQ
Sbjct 1660 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1718
Query 1663 LEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAK 1722
+ +KFN QEA+Y RAG AL+LA + E D + + +L+ A+L A
Sbjct 1719 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1778
Query 1723 RVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVC-GRDATQYLVQQESSF 1781
L ++C CG K + GV+AVM+ GTL+ +L G I C C GR + + F
Sbjct 1779 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGR--IVHCTKLNVPF 1835
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S P L + AN + G GHYTH+ D + K + G +T
Sbjct 1836 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1893
Query 1842 DVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLP-- 1898
D Y K + T T +Y LD V P L YY + YYT +PI +P
Sbjct 1894 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKV 1952
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGFTKPAS-RELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL + LN GF E VT +P GDVV Y +
Sbjct 1953 DGVYTNFKLVGHD--ICAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYF 2010
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKP-VDTSNSFEVLAVEDTQGMDNL 2016
KG + KP++W + + + + KP + N + VL+V D++
Sbjct 2011 KGCETFGKPVIWFCHDEASLNSLT---------YFNKPSFKSENRYSVLSV------DSV 2055
Query 2017 ACESQQPTSEEVVENPTIQKEV-IECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
+ ESQ V+E+ KEV ++ KT ++ +I+ + +KV + L D+
Sbjct 2056 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2115
Query 2076 YVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAK 2135
Y+ + NELS + T+ + I + L ++ Q +
Sbjct 2116 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPITIPIDLLCLRD-DNQTLLVPKIFKA 2174
Query 2136 RLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYV 2195
R + F ++ ++F +F L FT T IA ++ L L
Sbjct 2175 RAIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAFQTF 2228
Query 2196 KSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGV----------------LLSNFGAPSY 2239
+ F K F + + L + + + F + + + FG +
Sbjct 2229 RWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTI 2288
Query 2240 CNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL--DLTI 2297
C+ +L + T FC GSF C +C SG D LD+Y A++ +Q + L +++
Sbjct 2289 CDFYSKLGVG----FTSHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDYVSL 2344
Query 2298 LGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVS 2355
+ L E V+ Y L+T +FY L +Q+F + F+ + WL+ FI+ + M P
Sbjct 2345 VKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAF 2404
Query 2356 AMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYA 2415
++R YI + Y + HI+ GC + C+ CYKRN + RV+C+TIV G+ R + + A
Sbjct 2405 VLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITA 2464
Query 2416 NGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKN 2475
NGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2465 NGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVG 2524
Query 2476 GALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSAS 2535
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + S D + +A
Sbjct 2525 CMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVE--SDADRANFLNAV 2582
Query 2536 VYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHS 2595
V+Y+Q + +PILL+D+ L++ + V+ MFD YVDTF + F V + V AH+
Sbjct 2583 VFYAQSLYRPILLVDKKLITTACNGISVTQIMFDVYVDTFMSHFDVDRKSFNNFVNIAHA 2642
Query 2596 ELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTY 2654
L +GV L+ VL TFV R+ +D+DV+T+ + + + + + LE T ++ NN + TY
Sbjct 2643 SLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVPTY 2702
Query 2655 NKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNN 2714
K +N+ DLG I A+H+ VAK N+S IW + + L+ L+ +++ A K
Sbjct 2703 LKSDNIVAADLGVLIQNGAKHVQGNVAKVANISCIWFIDAFNQLTADLQHKLKKACVKTG 2762
Query 2715 IPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLS 2774
+ +LT V ++TT SLKGG ++S ++ +L+C + + + ++P +++
Sbjct 2763 LKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPTYSVY 2819
Query 2775 IHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGS--YKNDKSCPVVA 2832
D + +K I +GV RDI D CFANK FD W+ GS Y N CP+V
Sbjct 2820 KSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDCPIVV 2879
Query 2833 AIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVL 2892
A++ +IG + +P VLR LHFL F++ CYTP I Y+DF S CVL
Sbjct 2880 AVMDEDIGSTMFNVPTKVLR-YGFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVL 2938
Query 2893 AAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVR 2951
++ CT+FK G P PYCY +++ + Y+ L P TRY L + + I+FP+ EG VR
Sbjct 2939 SSLCTMFKRGDGTPHPYCYTDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVR 2998
Query 2952 VVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPL 3011
+V T YCR G CE +E GIC + + WVLNN++YR++ G FCG D +L F+ L
Sbjct 2999 IVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDFFDLFYQFFSSL 3058
Query 3012 VQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCL 3071
++P+ ++AS + G I+AI+V YY +K +R FG+Y VV N +++ ++F +L +
Sbjct 3059 IRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFV 3118
Query 3072 VPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCH 3131
Y VY+ FY Y+T YF +++S + HLQW M+ I+PFW YV + H
Sbjct 3119 FQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVL 3178
Query 3132 WFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKY 3191
W F+ Y RK + N + STFEE +L TF++ K+ Y +L++ + YNRYL+LYNKY
Sbjct 3179 WLFS-YCRK-IGVNVCSDSTFEETSLTTFMITKDSYCRLKNS--VSDVAYNRYLSLYNKY 3234
Query 3192 KYFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPS 3250
+Y+SG +DT +YREAAC LAKA+ F+ N+G DVLYQPP S++++ LQSG KM P+
Sbjct 3235 RYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPT 3294
Query 3251 GKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQA 3310
K+E C+V VT G+ TLNGLWLDD VYCPRHVIC + +M P+Y LL R + F + +
Sbjct 3295 SKIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDFTIMS 3354
Query 3311 GNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAM 3370
G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + M
Sbjct 3355 GRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAFHVTM 3414
Query 3371 RPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQT 3430
R ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q
Sbjct 3415 RSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGNFYGPYRDAQV 3474
Query 3431 AQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL 3490
Q D T+NV+AWLYAA++N WF+ ++ DFN+ AM + + D V L
Sbjct 3475 VQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADLV--L 3532
Query 3491 GPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFK 3550
L++ TG+++ + AA+K L G GR ILGS EDE P DV +Q +GV Q K K
Sbjct 3533 DALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTK 3591
Query 3551 KIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKH 3610
+ +K T +W+L++ I+ +W++F ++ + TL ++ + MLLVKHKH
Sbjct 3592 RFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLVKHKH 3650
Query 3611 AFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASAL-VL 3668
+L ++++P L T+ Y N +V + WL +++ + + V Y L V
Sbjct 3651 FYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYE-VFYGCILCVF 3709
Query 3669 LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTI 3728
I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ T + TTI
Sbjct 3710 AIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLFITAFLGTYTW----TTI 3765
Query 3729 MFLARA-IVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGV 3787
+ LA A IV + F ++ I+L Y F+GY CY+G F LLN FR+ +GV
Sbjct 3766 LSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMGV 3825
Query 3788 YDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSV 3847
Y+Y +S QE RYMN+ GL PP++S +A LN+KLLGIGG P I+V+ +QSK++DVKC +V
Sbjct 3826 YNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCANV 3885
Query 3848 VLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD---- 3903
VLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL S AVD
Sbjct 3886 VLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFSNPAAVDTKCL 3945
Query 3904 --INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKS 3960
I+ + ++ + + LQA+ SEF ++ S+ Y A++ A +G ++ +K+L+K+
Sbjct 3946 ASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKA 4005
Query 3961 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4020
N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN
Sbjct 4006 CNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQ 4065
Query 4021 ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD 4080
ALN+I++NA GCVPL+ IP A L +++PD + D TYA ++W IQ V D
Sbjct 4066 ALNSILDNAVKGCVPLSAIPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQTVQD 4125
Query 4081 ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGT--- 4135
AD QL++I++D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4126 ADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDIN 4181
Query 4136 --TQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFV 4193
T C YYNN GR V A+LSD LK+ + K DG + EL+PPC+F
Sbjct 4182 CNIPTQC-------YYNNVSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFS 4233
Query 4194 TDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDP 4253
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VDP
Sbjct 4234 IQDVKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDP 4293
Query 4254 AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDH 4313
K Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++H
Sbjct 4294 KKTYLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEH 4353
Query 4314 PNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADA 4373
P+ G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D
Sbjct 4354 PDVDGICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SSVAVQSKDL 4411
Query 4374 STFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEG 4432
+ FLNRV G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D++G
Sbjct 4412 N-FLNRVRGTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDG 4470
Query 4433 NLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYT 4492
N LD +FVVKR + Y E+T Y L K C VA HDFF F +DG VPHI R+ L+KYT
Sbjct 4471 NKLDKFFVVKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRRNLSKYT 4530
Query 4493 MADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVR 4552
M DL YALRHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG
Sbjct 4531 MLDLCYALRHFDRNDCSILCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFN 4590
Query 4553 QSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMP 4612
++LL TV F D + + G+VGVLTLDNQDL G WYDFGDF+Q APG GV + DSYYS +MP
Sbjct 4591 RALLNTVIFADTLVEVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMP 4650
Query 4613 ILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLD 4672
+LT+ L E ++ + +DL++YDFT+ +L LF++YFKYW YHPN ++C +
Sbjct 4651 MLTMCHVLDCELFVNDSYRQ----FDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDN 4706
Query 4673 DRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHS 4732
DRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H
Sbjct 4707 DRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHR 4766
Query 4733 SRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFA 4792
RLS K+LL+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F
Sbjct 4767 YRLSLKDLLLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFV 4826
Query 4793 VSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCY 4852
SKG FKEGS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ Y
Sbjct 4827 KSKGLFKEGSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIY 4886
Query 4853 DGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMN 4912
DGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMN
Sbjct 4887 DGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMN 4946
Query 4913 LKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLK 4972
LKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+
Sbjct 4947 LKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLR 5006
Query 4973 TVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVL 5032
+ DV+ P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ RFYRLANECAQVL
Sbjct 5007 HLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVL 5066
Query 5033 SEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNL 5092
SE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNL
Sbjct 5067 SEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNL 5126
Query 5093 QHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFK 5152
Q RLY +YR VD+ FV+E+Y +L KHFSMMILSDD VVCYNS+YA +G +A+I F+
Sbjct 5127 QKRLYSNVYRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYANKGYIANISAFQ 5186
Query 5153 AVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCF 5212
VLYYQNNVFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCF
Sbjct 5187 QVLYYQNNVFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCF 5246
Query 5213 VDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMY 5272
VDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD Y
Sbjct 5247 VDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLGTQILDSY 5306
Query 5273 SVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCY 5332
SV+L+ + ++ E FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCY
Sbjct 5307 SVILSTCDGLKFTEESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCY 5366
Query 5333 DHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFG 5392
DHV++T+HK VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFG
Sbjct 5367 DHVMATNHKYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFG 5426
Query 5393 LYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGI 5452
LYK +C GS + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY
Sbjct 5427 LYKQSCTGSPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYAS 5486
Query 5453 ATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVY 5512
AT++E++SDRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V Y
Sbjct 5487 ATIQEIVSDREVILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYY 5546
Query 5513 RGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANY 5570
R TTTYKL++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y ++ F +NVANY
Sbjct 5547 RATTTYKLSIGDVFVLTSHSVASLSAPTLVPQENYASIRFSSVY---SVPLVFQNNVANY 5603
Query 5571 QKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDK 5630
Q +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+
Sbjct 5604 QHIGMKRYCTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNIND 5663
Query 5631 CSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNA 5690
C+RIIPA+ RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NA
Sbjct 5664 CTRIIPAKVRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINA 5723
Query 5691 RLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIV 5750
R++AKHYVYIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV
Sbjct 5724 RIKAKHYVYIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIV 5783
Query 5751 DTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKA 5810
+TVSALVYDNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W A
Sbjct 5784 ETVSALVYDNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSA 5843
Query 5811 VFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAK 5870
VFISPYNSQN VA ++LG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK
Sbjct 5844 VFISPYNSQNYVAKRVLGVQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRAK 5903
Query 5871 IGILCIMSDRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKIITGLHPTQAPTHL 5929
GI C+MS+ L++ L F +L + + TL + T LFKDCSK G HP AP+ L
Sbjct 5904 KGIFCVMSNMQLFESLNFITLPLDKIQNQTLPRLHCTTNLFKDCSKSCLGYHPAHAPSFL 5963
Query 5930 SVDIKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAW 5988
+VD K+K E L V++ +TY RLIS+MGFK++ ++GY +FIT++EAI+ VR W
Sbjct 5964 AVDDKYKVNENLAVNLNICEPVLTYSRLISLMGFKLDLTLDGYSKLFITKDEAIKRVRGW 6023
Query 5989 IGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQF 6048
+GFDVEG HATR+ +GTN PLQ+GFSTGV+ V TG + F + AK PPG++F
Sbjct 6024 VGFDVEGAHATRENIGTNFPLQIGFSTGVDFVVEATGLFAERDCYTFKKTVAKAPPGEKF 6083
Query 6049 KHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERT 6108
KHLIPLM KG W++VRI+IVQMLSD L LSD VVF+ W+ FELT ++YF K+G E
Sbjct 6084 KHLIPLMSKGQKWDIVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELN 6143
Query 6109 CCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGN 6168
C +C RATC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD C VH
Sbjct 6144 CNVCSNRATCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKG 6203
Query 6169 AHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKF 6228
AHVAS DAIMTRCLA+++CF K V+W++EYPII +E+ +N++CR +Q +++K+A+L +++
Sbjct 6204 AHVASADAIMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRY 6263
Query 6229 PVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWN 6288
+ +DIGNPK + CV + E+KFYDA P A +++LFY Y H D F DG+C+FWN
Sbjct 6264 NLCYDIGNPKGLACVK--DYEFKFYDAFPV---AKSVKQLFYVYDVHKDNFKDGLCMFWN 6318
Query 6289 CNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFY 6348
CNVD+YP+N+IVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFY
Sbjct 6319 CNVDKYPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFY 6378
Query 6349 YSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGF 6408
YSD+PC +DYVPL+SATCITRCNLGGAVC HA EY YL++YN++ +AGF
Sbjct 6379 YSDTPCVYVDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEEYCNYLESYNIVTTAGF 6438
Query 6409 SLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGID 6468
+ W+YK FD YNLWNTFT LQSLENV YN+VN GH+DG GE P +I+N+ V K++ +D
Sbjct 6439 TFWVYKTFDFYNLWNTFTTLQSLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKINNVD 6498
Query 6469 VEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTI 6528
IF+N T+ P N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +++ ST
Sbjct 6499 TVIFKNNTSFPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTY 6558
Query 6529 GVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQ 6588
GVC TD+ +L +LFDGR G ++ FR ARNGV I+ + L+ KGP +
Sbjct 6559 GVCKYTDL------KFIENLNILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKGPQR 6612
Query 6589 ASVNGVTL--IGESVKTQFNYFKKVDG---IIQQL----------PE------------- 6620
A +NGV + +GE +K +F + + DG I + P+
Sbjct 6613 ADLNGVIVDKVGE-LKVEFWFAMRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGNVIG 6671
Query 6621 -------TYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQ 6673
T FTQSR L F+PRS +E DF+++ + FI +Y LE YAF+HIVYG F+H
Sbjct 6672 NDALTRFTIFTQSRVLSSFEPRSDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFNHKV 6731
Query 6674 LGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVE 6733
+GGLHL+IGL +R + S L +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV
Sbjct 6732 IGGLHLLIGLFRRLKKSNLLIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVS 6791
Query 6734 IIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQ 6793
I+KS +LS +SKVV + +D+ + FMLWC D + TFYPK+QA+ W+PG +MP LYK
Sbjct 6792 IVKSLNLSCVSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATNDWKPGYSMPVLYKYL 6851
Query 6794 RMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGV 6853
+ LE+ L NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK V
Sbjct 6852 NVPLERVSLWNYGKPINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEV 6911
Query 6854 APGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKH 6913
APG+AVLRQWLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TK+
Sbjct 6912 APGSAVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKN 6971
Query 6914 VTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVN 6973
+ N SK+GFFTY+C I+ KL+LGGS+A+KITE SWNADLYKLM F++WT F TNVN
Sbjct 6972 IGDYNVSKDGFFTYICHLIRDKLSLGGSVAIKITEFSWNADLYKLMSCFAFWTVFCTNVN 7031
Query 6974 ASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTA 7033
ASSSE FLIG NYLGK +IDG MHANY+FWRN+ +YSLFDM+KF LKL GTA
Sbjct 7032 ASSSEGFLIGINYLGKSSFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMTKFSLKLAGTA 7091
Query 7034 VMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
V++L+ +Q+ND++YSL+E+G+L++R+ + + D LVN
Sbjct 7092 VVNLRPDQLNDLVYSLIERGKLLVRDTRKEIFVGDSLVN 7130
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 55/157 (35%), Positives = 80/157 (51%), Gaps = 2/157 (1%)
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
L +T NV DI+ A+ VIVN AN H+ HGGGVA A+ A KE+ +
Sbjct 1308 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1367
Query 1070 KLNGPLTVGGSCLLSGHNLAKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQDILLAPLL 1127
K G VG + +G L K L++VGP+ + + LL AY++ N+ D L+ L+
Sbjct 1368 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1427
Query 1128 SAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
SAGIF SL + V QV + N+K ++ +
Sbjct 1428 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDII 1464
Score = 79.3 bits (194), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 89/362 (25%), Positives = 158/362 (44%), Gaps = 48/362 (13%)
Query 616 LLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCV 675
LLGTT+ + + W L A W +L L+ G F + + + + I D
Sbjct 615 LLGTTL--VNKMVNWFNTMLDASAP--ATGW-LLYQLLNGFFVVSQANLNFVA-LIPDYA 668
Query 676 KCFIDVVNKALEMCIDQVTIAGAK----LRSLN-----LGEVFIAQSKGLYRQCIRGKEQ 726
K ++ ++ ++ VT+ K L+++N +G F S GL I G
Sbjct 669 KILVNKFYTFFKLLLECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGL----IPG--- 721
Query 727 LQLLMPLKA-PKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSF---TNGAIVGTP 782
++P A +++ F EG +E V++++ +E +++ + S+ V
Sbjct 722 --FVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEKI 772
Query 783 VCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGG--APIKG--VTFGED-TVWEVQGY 837
++ + + + DK P ++ N+ L P G V F E V E+
Sbjct 773 CIIDNMYMGKCGDK-----FFPIVMNDKNICLLDHAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 838 KNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD---LLTNM 894
V++ F+LD D +L + CS + VE G V +F VV +A+ L + + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQV 887
Query 895 GIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTE 954
L++ + YLFD+AG+E +SRMYC+F D E+ +E E+ ID E +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 955 DD 956
+D
Sbjct 948 ED 949
Score = 44.3 bits (103), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 38/137 (28%), Positives = 60/137 (44%), Gaps = 14/137 (10%)
Query 1637 QVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSN 1696
+V GL S NC+L SVLL +Q+L KF A++ + + G +F +L
Sbjct 1097 KVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTTIP 1156
Query 1697 KTV--GELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYD 1754
K + + G V + L ++ + N C CG + L G++AV + G +
Sbjct 1157 KAIVLPQGGYVADFAYWFLNQFDINAYA---NWCCLKCG-FSFDLNGLDAVFFYGDI--- 1209
Query 1755 NLKTGVSIPCVCGRDAT 1771
VS C CG + T
Sbjct 1210 -----VSHVCKCGHNMT 1221
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 5312 bits (13780), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2722/5614 (48%), Positives = 3653/5614 (65%), Gaps = 167/5614 (3%)
Query 1543 KTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
K I V TVD N + + + +G+ G + DG DVTK+K + K + +
Sbjct 1650 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1709
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ 1662
A + D+ L Y + L KW G S + + NNCY++ L LQ
Sbjct 1710 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1768
Query 1663 LEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAK 1722
+ +KFN QEA+Y RAG AL+LA + E D + + +L+ A+L A
Sbjct 1769 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1828
Query 1723 RVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVC-GRDATQYLVQQESSF 1781
L ++C CG K + GV+AVM+ GTL+ +L G I C C GR + + F
Sbjct 1829 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGR--IVHCTKLNVPF 1885
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S P L + AN + G GHYTH+ D + K + G +T
Sbjct 1886 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1943
Query 1842 DVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLP-- 1898
D Y K + T T +Y LD V P L YY + YYT +PI +P
Sbjct 1944 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKV 2002
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGFTKPAS-RELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL + LN GF E VT +P GDVV Y +
Sbjct 2003 DGVYTNFKLVGHD--ICAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYF 2060
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKP-VDTSNSFEVLAVEDTQGMDNL 2016
KG + KP++W + + + + KP + N + VL+V D++
Sbjct 2061 KGCETFGKPVIWFCHDEASLNSLT---------YFNKPSFKSENRYSVLSV------DSV 2105
Query 2017 ACESQQPTSEEVVENPTIQKEV-IECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
+ ESQ V+E+ KEV ++ KT ++ +I+ + +KV + L D+
Sbjct 2106 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2165
Query 2076 YVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAK 2135
Y+ + NELS + T+ + I + L ++ Q +
Sbjct 2166 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPITIPIDLLCLRD-DNQTLLVPKIFKA 2224
Query 2136 RLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYV 2195
R + F ++ ++F +F L FT T IA ++ L L
Sbjct 2225 RAIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAFQTF 2278
Query 2196 KSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGV----------------LLSNFGAPSY 2239
+ F K F + + L + + + F + + + FG +
Sbjct 2279 RWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTI 2338
Query 2240 CNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL--DLTI 2297
C+ +L + T FC GSF C +C SG D LD+Y A++ +Q + L +++
Sbjct 2339 CDFYSKLGVG----FTSHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDYVSL 2394
Query 2298 LGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVS 2355
+ L E V+ Y L+T +FY L +Q+F + F+ + WL+ FI+ + M P
Sbjct 2395 VKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAF 2454
Query 2356 AMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYA 2415
++R YI + Y + HI+ GC + C+ CYKRN + RV+C+TIV G+ R + + A
Sbjct 2455 VLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITA 2514
Query 2416 NGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKN 2475
NGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2515 NGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVG 2574
Query 2476 GALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSAS 2535
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + S D + +A
Sbjct 2575 CMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVE--SDADRANFLNAV 2632
Query 2536 VYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHS 2595
V+Y+Q + +PILL+D+ L++ + V+ MFD YVDTF + F V + V AH+
Sbjct 2633 VFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVNIAHA 2692
Query 2596 ELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTY 2654
L +GV L+ VL TFV R+ +D+DV+T+ + + + + + LE T ++ NN + TY
Sbjct 2693 SLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVPTY 2752
Query 2655 NKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNN 2714
K +N+ DLG I A+H+ VAK+ N+S IW + + L+ L+ +++ A K
Sbjct 2753 LKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDAFNQLTADLQHKLKKACVKTG 2812
Query 2715 IPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLS 2774
+ +LT V ++TT SLKGG ++S ++ +L+C + + + ++P +++
Sbjct 2813 LKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFVSLICFI---LLWALLPTYSVY 2869
Query 2775 IHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGS--YKNDKSCPVVA 2832
D + +K I +GV RDI D CFANK FD W+ GS Y N CP+V
Sbjct 2870 KSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDCPIVV 2929
Query 2833 AIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVL 2892
A++ +IG + +P VLR LHFL F++ CYTP I Y+DF S CVL
Sbjct 2930 AVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVL 2988
Query 2893 AAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVR 2951
++ CT+FK G P PYCY +++ + Y+ L P TRY L + + I+FP+ EG VR
Sbjct 2989 SSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVR 3048
Query 2952 VVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPL 3011
+V T YCR G CE +E GIC + + WVLNN++YR++ G FCG D +L F+ L
Sbjct 3049 IVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQFFSSL 3108
Query 3012 VQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCL 3071
++P+ ++AS + G I+AI+V YY +K +R FG+Y VV N +++ ++F +L +
Sbjct 3109 IRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVVVWCINFLMLFV 3168
Query 3072 VPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCH 3131
Y VY+ FY Y+T YF +++S + HLQW M+ I+PFW YV + H
Sbjct 3169 FQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVL 3228
Query 3132 WFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKY 3191
W F+ Y RK + N + STFEE +L TF++ K+ Y +L++ + YNRYL+LYNKY
Sbjct 3229 WLFS-YCRK-IGVNVCSDSTFEETSLTTFMITKDSYCRLKNS--VSDVAYNRYLSLYNKY 3284
Query 3192 KYFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPS 3250
+Y+SG +DT +YREAAC LAKA+ F+ N+G DVLYQPP S++++ LQSG KM P+
Sbjct 3285 RYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPT 3344
Query 3251 GKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQA 3310
K+E C+V VT G+ TLNGLWLDD VYCPRHVIC++ +M P+Y LL R + F + +
Sbjct 3345 SKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCRVTLGDFTIMS 3404
Query 3311 GNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAM 3370
G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + M
Sbjct 3405 GRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNGRPQGAFHVTM 3464
Query 3371 RPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQT 3430
R ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q
Sbjct 3465 RSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYRDAQV 3524
Query 3431 AQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL 3490
Q D T+NV+AWLYAA++N WF+ + DFN+ AM + + D V L
Sbjct 3525 VQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFSQVKADLV--L 3582
Query 3491 GPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFK 3550
L++ TG+++ + AA+K L G GR ILGS EDE P DV +Q +GV Q K K
Sbjct 3583 DALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTK 3641
Query 3551 KIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKH 3610
+ +K T +W+L++ I+ +W++F ++ + TL ++ + MLLVKHKH
Sbjct 3642 RFIKETIYWILISTFLFSCIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLVKHKH 3700
Query 3611 AFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASAL-VL 3668
+L ++++P L T+ Y N +V + WL +++ + + V Y L V
Sbjct 3701 FYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYE-VFYGCILCVF 3759
Query 3669 LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTI 3728
I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ T + TTI
Sbjct 3760 AIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLFITAFLGTYTW----TTI 3815
Query 3729 MFLARA-IVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGV 3787
+ LA A IV + F ++ I+L Y F+GY CY+G F LLN FR+ +GV
Sbjct 3816 LSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMGV 3875
Query 3788 YDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSV 3847
Y+Y +S QE RYMN+ GL PP++S +A LN+KLLGIGG P I+V+ +QSK++DVKC +V
Sbjct 3876 YNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCANV 3935
Query 3848 VLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD---- 3903
VLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3936 VLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDTKCL 3995
Query 3904 --INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKS 3960
I+ + ++ + + LQA+ SEF ++ S+ Y A++ A +G ++ +K+L+K+
Sbjct 3996 ASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKA 4055
Query 3961 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4020
N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN
Sbjct 4056 CNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQ 4115
Query 4021 ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD 4080
ALN+I++NA GCVPL+ IP A L +V+PD + D TYA ++W IQ V D
Sbjct 4116 ALNSILDNAVKGCVPLSAIPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHIQTVQD 4175
Query 4081 ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGTTQT 4138
AD QL++I++D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4176 ADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDMN 4231
Query 4139 ACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPK 4198
+ YYNN GR V A+LSD LK+ + K DG + EL+PPC+F K
Sbjct 4232 C--NIPTQCYYNNGSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFSIQDVK 4288
Query 4199 GPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYK 4258
G K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VDP K Y
Sbjct 4289 GLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKTYL 4348
Query 4259 DYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKG 4318
DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+ G
Sbjct 4349 DYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDVDG 4408
Query 4319 FCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
C L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D + FLN
Sbjct 4409 ICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SSVAVQSKDLN-FLN 4465
Query 4379 RVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDS 4437
RV G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D++GN LD
Sbjct 4466 RVRGTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDGNKLDK 4525
Query 4438 YFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLV 4497
+FVVKR + Y E+T Y L K C VA HDFF F +DG VPHI R+ L+KYTM DL
Sbjct 4526 FFVVKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRRNLSKYTMLDLC 4585
Query 4498 YALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLK 4557
YALRHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG ++LL
Sbjct 4586 YALRHFDRNDCSILCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFNRALLN 4645
Query 4558 TVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLT 4617
TV F D + + G+VGVLTLDNQDL G WYDFGDF+Q APG GV + DSYYS +MP+LT+
Sbjct 4646 TVIFADTLVEVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMPMLTMC 4705
Query 4618 RALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCIL 4677
L E ++ + +DL++YDFT+ +L LF++YFKYW YHPN ++C +DRCI+
Sbjct 4706 HVLDCELFVNDSYRQ----FDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDNDRCII 4761
Query 4678 HCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSF 4737
HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS
Sbjct 4762 HCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHRYRLSL 4821
Query 4738 KELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGF 4797
K+LL+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F SKG
Sbjct 4822 KDLLLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFVKSKGL 4881
Query 4798 FKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCI 4857
FKEGS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGGCI
Sbjct 4882 FKEGSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGGCI 4941
Query 4858 NANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAI 4917
A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMNLKYAI
Sbjct 4942 PASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMNLKYAI 5001
Query 4918 SAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSD 4977
SAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + D
Sbjct 5002 SAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRHLIKD 5061
Query 4978 VETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVM 5037
V+ P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ RFYRLANECAQVLSE+VM
Sbjct 5062 VDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVLSEIVM 5121
Query 5038 CGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLY 5097
CGG YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNLQ RLY
Sbjct 5122 CGGCYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNLQKRLY 5181
Query 5098 ECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYY 5157
+YR VD+ FV+E+Y +L KHFSMMILSDD VVCYNS+YA++G +A+I F+ VLYY
Sbjct 5182 SNVYRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYASKGYIANISVFQQVLYY 5241
Query 5158 QNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIV 5217
QNNVFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCFVDD++
Sbjct 5242 QNNVFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCFVDDLL 5301
Query 5218 KTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLT 5277
KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD YSV+L+
Sbjct 5302 KTDSVLLIERFVSLAIDAYPLVHHENEEYQKVFRVYLEYIKKLYNDLGTQILDSYSVILS 5361
Query 5278 NDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVIS 5337
+ ++ E FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV++
Sbjct 5362 TCDGLKFTEESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHVMA 5421
Query 5338 TSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNT 5397
T+HK VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFGLYK +
Sbjct 5422 TNHKYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFGLYKQS 5481
Query 5398 CVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVRE 5457
C GS + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY AT++E
Sbjct 5482 CTGSPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYASATIQE 5541
Query 5458 VLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTT 5517
++SDRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V YR TTT
Sbjct 5542 IVSDREVILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYYRATTT 5601
Query 5518 YKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGM 5575
YKL++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y ++ F +NVANYQ +GM
Sbjct 5602 YKLSIGDVFVLTSHSVASLSAPTLVPQENYASIRFSSVY---SVPLVFQNNVANYQHIGM 5658
Query 5576 QKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5635
++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RII
Sbjct 5659 KRYCTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNINDCTRII 5718
Query 5636 PARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK 5695
PA+ RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NAR++AK
Sbjct 5719 PAKVRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINARIKAK 5778
Query 5696 HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSA 5755
HYVYIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV+TVSA
Sbjct 5779 HYVYIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIVETVSA 5838
Query 5756 LVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISP 5815
LVYDNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W AVFISP
Sbjct 5839 LVYDNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSAVFISP 5898
Query 5816 YNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILC 5875
YNSQN VA ++LG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK GI C
Sbjct 5899 YNSQNYVAKRVLGVQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKGIFC 5958
Query 5876 IMSDRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKIITGLHPTQAPTHLSVDIK 5934
+MS+ L++ L F +L + + TL + T LFKDCSK G HP AP+ L+VD K
Sbjct 5959 VMSNMQLFESLNFITLPLDKIQNQTLPRLHCTTNLFKDCSKSCLGYHPAHAPSFLAVDDK 6018
Query 5935 FKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDV 5993
+K E L V++ +TY RLIS+MGFK++ ++GY +FIT++EAI+ VR W+GFDV
Sbjct 6019 YKVNENLAVNLNICEPVLTYSRLISLMGFKLDLTLDGYSKLFITKDEAIKRVRGWVGFDV 6078
Query 5994 EGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIP 6053
EG HATR+ +GTN PLQ+GFSTGV+ V TG + F + AK PPG++FKHLIP
Sbjct 6079 EGAHATRENIGTNFPLQIGFSTGVDFVVEATGLFAERDCYTFKKTVAKAPPGEKFKHLIP 6138
Query 6054 LMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCD 6113
LM KG W++VRI+IVQMLSD L LSD VVF+ W+ FELT ++YF K+G E C +C
Sbjct 6139 LMSKGQKWDIVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELNCNVCS 6198
Query 6114 KRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVAS 6173
RATC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD C VH AHVAS
Sbjct 6199 NRATCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKGAHVAS 6258
Query 6174 CDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHD 6233
DAIMTRCLA+++CF K V+W++EYPII +E+ +N++CR +Q +++K+A+L +++ + +D
Sbjct 6259 ADAIMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRYNLCYD 6318
Query 6234 IGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDR 6293
IGNPK + CV + E+KFYDA P A +++LFY Y H D F DG+C+FWNCNVD+
Sbjct 6319 IGNPKGLACVK--DYEFKFYDAFPV---AKSVKQLFYVYDVHKDNFKDGLCMFWNCNVDK 6373
Query 6294 YPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSP 6353
YP+N+IVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFYYSD+P
Sbjct 6374 YPSNSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFYYSDTP 6433
Query 6354 CESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIY 6413
C +DYVPL+SATCITRCNLGGAVC HA EY YL++YN++ +AGF+ W+Y
Sbjct 6434 CVYVDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEEYCNYLESYNIVTTAGFTFWVY 6493
Query 6414 KQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFE 6473
K FD YNLWNTFT LQSLENV YN+VN GH+DG GE P +I+N+ V K++ +D IF+
Sbjct 6494 KNFDFYNLWNTFTTLQSLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKINNVDTVIFK 6553
Query 6474 NKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTM 6533
N T+ P N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +++ ST GVC
Sbjct 6554 NNTSFPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVCKY 6613
Query 6534 TDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNG 6593
TD+ +L +LFDGR G ++ FR ARNGV I+ + L+ KGP +A +NG
Sbjct 6614 TDL------KFIENLNILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKGPQRADLNG 6667
Query 6594 VTL--IGESVKTQFNYFKKVDG---IIQQL----------PE------------------ 6620
V + +GE +K +F + + DG I + P+
Sbjct 6668 VIVDKVGE-LKVEFWFAMRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGNVIGNDALT 6726
Query 6621 --TYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLH 6678
T FTQSR L F+PRS +E DF+++ + FI +Y LE YAF+HIVYG F+H +GGLH
Sbjct 6727 RFTIFTQSRVLSSFEPRSDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFNHKVIGGLH 6786
Query 6679 LMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQ 6738
L+IGL +R + S L +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS
Sbjct 6787 LLIGLFRRKKKSNLLIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVSIVKSL 6846
Query 6739 DLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLE 6798
+LS +SKVV + +D+ + FMLWC D + TFYPK+QA+ W+PG +MP LYK + LE
Sbjct 6847 NLSCVSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATNDWKPGYSMPVLYKYLNVPLE 6906
Query 6799 KCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTA 6858
+ L NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+A
Sbjct 6907 RVSLWNYGKPINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEVAPGSA 6966
Query 6859 VLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKEN 6918
VLRQWLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TK++ N
Sbjct 6967 VLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKNIGDYN 7026
Query 6919 DSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSE 6978
SK+GFFTY+C I+ KL+LGGS+A+KITE SWNADLYKLM F++WT F TNVNASSSE
Sbjct 7027 VSKDGFFTYICHLIRDKLSLGGSVAIKITEFSWNADLYKLMSCFAFWTVFCTNVNASSSE 7086
Query 6979 AFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLK 7038
FLIG NYLGK +IDG MHANY+FWRN+ +YSLFDM+KF LKL GTAV++L+
Sbjct 7087 GFLIGINYLGKSSFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMTKFSLKLAGTAVVNLR 7146
Query 7039 ENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
+Q+ND++YSL+E+G+L++R+ + + D LVN
Sbjct 7147 PDQLNDLVYSLIERGKLLVRDTRKEIFVGDSLVN 7180
Score = 83.6 bits (205), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 55/157 (35%), Positives = 80/157 (51%), Gaps = 2/157 (1%)
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
L +T NV DI+ A+ VIVN AN H+ HGGGVA A+ A KE+ +
Sbjct 1358 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1417
Query 1070 KLNGPLTVGGSCLLSGHNLAKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQDILLAPLL 1127
K G VG + +G L K L++VGP+ + + LL AY++ N+ D L+ L+
Sbjct 1418 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1477
Query 1128 SAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
SAGIF SL + V QV + N+K ++ +
Sbjct 1478 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDII 1514
Score = 79.3 bits (194), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 89/362 (25%), Positives = 158/362 (44%), Gaps = 48/362 (13%)
Query 616 LLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCV 675
LLGTT+ + + W L A W +L L+ G+F + + + I D
Sbjct 615 LLGTTL--VNKMVNWFNTMLDASAP--ATGW-LLYQLLNGLFVVSQANFNFVA-LIPDYA 668
Query 676 KCFIDVVNKALEMCIDQVTIAGAK----LRSLN-----LGEVFIAQSKGLYRQCIRGKEQ 726
K ++ ++ ++ VT+ K L+++N +G F S GL I G
Sbjct 669 KILVNKFYTFFKLLLECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGL----IPG--- 721
Query 727 LQLLMPLKA-PKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSF---TNGAIVGTP 782
++P A +++ F EG +E V++++ +E +++ + S+ V
Sbjct 722 --FVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEKI 772
Query 783 VCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGG--APIKG--VTFGED-TVWEVQGY 837
++ + + + DK P ++ N+ L P G V F E V E+
Sbjct 773 CIIDNMYMGKCGDK-----FFPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 838 KNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD---LLTNM 894
V++ F+LD D +L + CS + VE G V +F VV +A+ L + + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQV 887
Query 895 GIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTE 954
L++ + YLFD+AG+E +SRMYC+F D E+ +E E+ ID E +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 955 DD 956
+D
Sbjct 948 ED 949
Score = 43.1 bits (100), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 37/137 (27%), Positives = 60/137 (44%), Gaps = 14/137 (10%)
Query 1637 QVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSN 1696
+V GL S NC+L SVLL +Q+L KF A++ + + G +F +L
Sbjct 1147 KVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTTIP 1206
Query 1697 KTV--GELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYD 1754
K + + G V + L ++ + N C CG + L G++A+ + G +
Sbjct 1207 KAIVLPQGGFVADFAYWFLNQFDINAYA---NWCCLKCG-FSFDLNGLDALFFYGDI--- 1259
Query 1755 NLKTGVSIPCVCGRDAT 1771
VS C CG + T
Sbjct 1260 -----VSHVCKCGHNMT 1271
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 5287 bits (13715), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2725/5572 (49%), Positives = 3627/5572 (65%), Gaps = 216/5572 (4%)
Query 1545 IKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL 1604
+ + TVD N + V + ++G+ G + DG +VTK K +N++GK FF D L
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQF---DNL 1621
Query 1605 RSE---AFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
SE A D+ L Y + L + KW+ G + K A+NNC+++ L LQ
Sbjct 1622 SSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQ 1681
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
L +KF QEA+ R+G A F +L+LA G+ D R+ + + +L A
Sbjct 1682 SLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGA 1741
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
+ CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG+ + V+ + F
Sbjct 1742 ICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPF 1799
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S PA KL +G AN + G+ + GHY H+ +++ D +++ K+++ G ++
Sbjct 1800 LICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLS 1857
Query 1842 DVFYKETSYTTTIKPV--SYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLP 1898
D Y + + T K V +Y LD V E +P L YY YYT++ I T
Sbjct 1858 DCLYLK-NLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKV 1916
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL D LN GF + E VT +P GDVV Y ++
Sbjct 1917 DGVYTNFKLI--GHTVCDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYE 1974
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFEVLAVEDTQGMDNL 2016
+G KP++W ++ + + + +P+ N F+VL V+D ++
Sbjct 1975 RGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFDVLKVDDVDDGGDI 2025
Query 2017 A-CESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
+ ++++P +++ ++K +V +VI+ +K + L D+
Sbjct 2026 SESDAKEPKEINIIKLSGVKKPF--------KVEDSVIVNDDTSEIKYVKSLSIVDVYDM 2077
Query 2076 YVENTSITIKKPNELSLALGLKTI---ATHGIAAINSVPWSKI-LAYVKPFLGQAAITTS 2131
++ ++ N LS A+ + TI G+ + S+P + L +KP
Sbjct 2078 WLTGCRCVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVF-------- 2128
Query 2132 NCAKRLAQRVFN--NYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLD 2189
N K + ++ N++ ++F LLF + + T +A K KL
Sbjct 2129 NVVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---KLTCKLVAL 2181
Query 2190 AGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSYCNGVRELY 2247
A N + K+S + A + + + + I F L G P++ + +
Sbjct 2182 AFKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIVQWI 2241
Query 2248 LNSSNVTTM-------------DFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK-L 2293
N+ ++ T+ +C GS C CL+G D LD+Y A++ +Q +
Sbjct 2242 KNTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFV 2301
Query 2294 DLT-ILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQ 2350
D T +L + E +++Y L+T +FY L +Q+ + + ++ W + ++S+
Sbjct 2302 DYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELLMLSTLHWSVRLLVSLAN 2361
Query 2351 MAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRS 2410
M P +R YI ASF ++ + H+ GC+ S C+ CYKRNR+ RV+C+TIV GM R
Sbjct 2362 MLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRY 2421
Query 2411 FYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDS 2470
+ V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2422 YDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTD 2481
Query 2471 VAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESA 2530
V + L++D+ GQ+TY+ S FV+ NL + K ++V+V + + D++
Sbjct 2482 VKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DKAN 2539
Query 2531 SKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALV 2590
+A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V + L AL+
Sbjct 2540 FLNAAVFYAQSLFRPILMVDKILITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALI 2599
Query 2591 ATAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNN 2649
ATAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE+T +SCNN
Sbjct 2600 ATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCNN 2659
Query 2650 FMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSA 2709
+ TY K +N+ DLG I +A+H+ VAK VS IW+V + LS + +++ A
Sbjct 2660 LVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKA 2719
Query 2710 AKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYI--- 2766
K + LT V+V+TT SLKGG + S +C + +LVC+I
Sbjct 2720 CCKTGLKLELTYNKQMANVSVLTTPFSLKGGAVFSY-------FVYVCFVLSLVCFIGLW 2772
Query 2767 -VMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYK 2823
+MP +T+ D YK + +GV RD+ D CFANK FD W+ G Y
Sbjct 2773 CLMPTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYS 2832
Query 2824 NDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYS 2883
N +CP+V A++ ++ G V +P VLR LHF+ SA G CYTP I YS
Sbjct 2833 NSMACPIVVAVVDQDFGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQISYS 2891
Query 2884 DFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SIIQFP 2942
+F S CVL++ CT+F A G P PYCY L++ + YS L P RY L + I+ P
Sbjct 2892 NFYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRLP 2951
Query 2943 NTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMN 3002
EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG D +
Sbjct 2952 EVLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFD 3011
Query 3003 LIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLF 3062
LI +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N +++
Sbjct 3012 LIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLGFYYLIKLKRAFGDYTSIVFVNVIVW 3071
Query 3063 LMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYV 3122
++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W +Y+
Sbjct 3072 CVNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYI 3131
Query 3123 FCISLKHCHWFFNNYLRK---RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3179
+ H W F+ Y R+ V +G TFEE AL TF++ K+ Y KL++ L
Sbjct 3132 SVVVSNHAFWVFS-YCRQLGTSVRSDG----TFEEMALTTFMITKDSYCKLKNS--LSDV 3184
Query 3180 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNS-GADVLYQPPQTSITSAV 3238
+NRYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F+N+ G+DVLYQPP S++++
Sbjct 3185 AFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSF 3244
Query 3239 LQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLL 3298
LQSG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +LL
Sbjct 3245 LQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLL 3304
Query 3299 IRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACY 3358
R ++ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA Y
Sbjct 3305 CRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAY 3364
Query 3359 NGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLE 3418
NG P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD
Sbjct 3365 NGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFN 3424
Query 3419 GKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYN 3478
G FYGP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+
Sbjct 3425 GDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNG 3484
Query 3479 YEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVR 3538
+ + D V + L++ TG+++ + AA+K L +NG GR I+GS EDE TP DV +
Sbjct 3485 FSQVKSDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVYQ 3541
Query 3539 QCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAI 3598
Q +G+ Q K ++VKG W++ + I+ +W++F +V N L T + +
Sbjct 3542 QLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCV 3600
Query 3599 AACAMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLK 3657
+ AMLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y
Sbjct 3601 ISLAMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYT 3659
Query 3658 DCVMYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVIS 3716
D V+Y L++ ++ +T R++ D + + VI++V Y G+ L++ I + ++ S
Sbjct 3660 DEVIYGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLAS 3717
Query 3717 VTSNYSGVVTTIMFLARAIV-FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
+ Y+ M A+ I +V V L F ++ +++ Y F+GY CY+GLF
Sbjct 3718 LFGTYTWTTALSMAAAKVIAKWVAVNV--LYFTDIPQIKIVLVCYLFIGYIISCYWGLFS 3775
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
L+N FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+
Sbjct 3776 LMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQF 3835
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK++DVKC + LL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL
Sbjct 3836 QSKLTDVKCANGGLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVL 3895
Query 3896 LSMQGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
+ AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G
Sbjct 3896 FANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGS 3955
Query 3950 S-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQT 4008
+ + LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QT
Sbjct 3956 ANQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQT 4015
Query 4009 MLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTY 4068
MLF+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TY
Sbjct 4016 MLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 4075
Query 4069 ASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVAL 4126
A +W+IQ + D+D QL EI S + WPL++ A R N SA LQNNEL P L
Sbjct 4076 AGNVWQIQTIQDSDGTNKQLHEI----SDDCNWPLVIIANRHNEVSATVLQNNELMPAKL 4131
Query 4127 RQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTEL 4186
+ +G QT T YYNNS G+ V A+LSD LK+ + K DG + EL
Sbjct 4132 KTQVVNSGPDQTCNTPTQC--YYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LEL 4188
Query 4187 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4246
+PPC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS
Sbjct 4189 DPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSL 4248
Query 4247 CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4306
CAF+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+Y
Sbjct 4249 CAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIY 4308
Query 4307 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP 4366
CR ++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC +
Sbjct 4309 CRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDT 4366
Query 4367 LMQSADASTFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRF 4425
+QS D + FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRF
Sbjct 4367 TVQSKD-TNFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRF 4425
Query 4426 QEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISR 4485
Q DE G+ LD +FVVKR ++ Y E Y VKDC VA HDFF F V+G VPHI R
Sbjct 4426 QRVDENGDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVR 4485
Query 4486 QRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYA 4545
+ LTKYTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY
Sbjct 4486 KDLTKYTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYK 4545
Query 4546 NLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDS 4605
LG ++L+ +F D + + G+VG+LTLDNQDLNG WYDFGD+V APGCGV I DS
Sbjct 4546 KLGPIFNRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADS 4605
Query 4606 YYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHP 4665
YYS +MP+LT+ AL E +++ +DL++YDFT+ +L LF++YFK+W YHP
Sbjct 4606 YYSYMMPMLTMCHALDCELYVN----NAYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHP 4661
Query 4666 NCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHN 4725
N ++C DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N
Sbjct 4662 NTVDCQDDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMN 4721
Query 4726 QDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFN 4785
DV+ H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN
Sbjct 4722 MDVDTHRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFN 4781
Query 4786 KDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVV 4845
+DFYDF +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV
Sbjct 4782 QDFYDFILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVV 4841
Query 4846 DKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVI 4905
KYF+ YDGGCI A QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+
Sbjct 4842 YKYFEIYDGGCIPAAQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVL 4901
Query 4906 PTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYG 4965
PT+TQMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYG
Sbjct 4902 PTLTQMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYG 4961
Query 4966 GWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLA 5025
GW +ML+ + DV+ P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ S RFYRLA
Sbjct 4962 GWDDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLA 5021
Query 5026 NECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIA 5085
NECAQVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI
Sbjct 5022 NECAQVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIE 5081
Query 5086 DKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLV 5145
D +R LQ RLY +YR+ VD FV E+Y +L KHFSMMILSDD VVCYNS+YA++G +
Sbjct 5082 DLSIRALQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYI 5141
Query 5146 ASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSR 5205
A+I F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYP PSR
Sbjct 5142 ANISAFQQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPVPSR 5201
Query 5206 ILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELT 5265
ILGAGCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL++EL
Sbjct 5202 ILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNELG 5261
Query 5266 GHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPF 5325
+LD YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P
Sbjct 5262 NQILDSYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPL 5321
Query 5326 LCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLC 5385
LCCKCCYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L
Sbjct 5322 LCCKCCYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLV 5381
Query 5386 ANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEET 5445
NG VFGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE
Sbjct 5382 MNGMVFGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEA 5441
Query 5446 FKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGD 5505
FK SY AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K +
Sbjct 5442 FKQSYASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSE 5501
Query 5506 YGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEF 5563
+ V YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y +R +Y L + F
Sbjct 5502 LTNGVYYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETF 5558
Query 5564 SSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKAL 5623
+NV NYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA
Sbjct 5559 QNNVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAY 5618
Query 5624 KYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNY 5683
K+L I+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY
Sbjct 5619 KFLNINDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNY 5678
Query 5684 DLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCR 5743
+LSV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC
Sbjct 5679 ELSVINARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCY 5738
Query 5744 RCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTR 5803
RCP EIVDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL
Sbjct 5739 RCPKEIVDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKA 5798
Query 5804 NPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN 5863
NP W KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFN
Sbjct 5799 NPLWHKAVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFN 5858
Query 5864 VAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVAT-LQAENVTGLFKDCSKIITGLHP 5922
VAITRAK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP
Sbjct 5859 VAITRAKKGILCVMSNMQLFEALQFTTLTVDKVPQAVETRVQCSTNLFKDCSKSYSGYHP 5918
Query 5923 TQAPTHLSVDIKFKTEGLCVDIPGIPKD-MTYRRLISMMGFKMNYQVNGYPNMFITREEA 5981
AP+ L+VD K+K G GI +TY RLIS+MGFK++ ++GY +FIT+EEA
Sbjct 5919 AHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEA 5978
Query 5982 IRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAK 6041
++ VRAW+GFD EG HATRD++GTN PLQLGFSTG++ V TG + F + AK
Sbjct 5979 VKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAK 6038
Query 6042 PPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFV 6101
PPG+QFKHLIPLM +G W+VVR +IVQM +D L LSD VV V WA FELT ++YF
Sbjct 6039 APPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFA 6098
Query 6102 KIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQ 6161
K+G E +C + KRAT +++ + Y CW HSV DY+YNP ++D+QQWG+ G+L SNHD
Sbjct 6099 KVGREISCNVSTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDL 6158
Query 6162 HCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKS 6221
+C VH AHVAS DAIMTRCLAV++CF ++W+VEYPII +EL +N++CR +Q +++K+
Sbjct 6159 YCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKA 6218
Query 6222 ALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTD 6281
A+L +++ + +DIGNPKAI CV + ++KFYDAQP ++ L Y + H D F D
Sbjct 6219 AMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPIVK---SVKTLLYFFEAHKDSFKD 6273
Query 6282 GVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNL 6341
G+C+FWNCNVD+YP NA+VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +L
Sbjct 6274 GLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHL 6333
Query 6342 KQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYN 6401
K +PFFYYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR+YL++YN
Sbjct 6334 KPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYN 6393
Query 6402 MMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVY 6461
+AGF+ W+YK FD YNLWNTFT+LQSLENV YN+V GH+ G AGE P +IIN+ V
Sbjct 6394 TATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVV 6453
Query 6462 TKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREA 6521
K+D DV IF N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY RE+
Sbjct 6454 AKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARES 6513
Query 6522 PAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLT 6581
+T GVC TD+ L VLFDGR G ++ F+ + NGV I+ VK L+
Sbjct 6514 IFCSNTYGVCMYTDL------KLIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLS 6567
Query 6582 PSKGPAQASVNGVTL--IGES---------------VKTQFNYFK--------------- 6609
+GP +A +NGV + +G++ + +QF+ +
Sbjct 6568 MIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNE 6627
Query 6610 --KVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYG 6667
V G T FTQSR + F R+ ME DF+ L D FIQ+Y LE YAFEHIVYG
Sbjct 6628 PGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYG 6687
Query 6668 DFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLL 6727
+F+ +GGLHL+IGL +R Q S L +++F+ DS++ +YFITD ++G SK VC+VID+L
Sbjct 6688 NFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDIL 6747
Query 6728 LDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMP 6787
LDDFV ++KS +L+ +SKVV V +D+ + FMLWC D V TFYP+LQA+ W+PG +MP
Sbjct 6748 LDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMP 6807
Query 6788 NLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGA 6847
LYK +E+ L NYG+ +P G MMNVAKYTQLCQYLNT TLAVP N RV+H GA
Sbjct 6808 VLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNTRVLHLGA 6867
Query 6848 GSDKGVAPGTAV----------LRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTAN 6897
GS+KGVAPG+AV LRQWLP GT+LV +DL FVSD+ +T GDC T+
Sbjct 6868 GSEKGVAPGSAVLRQWLPAGTILRQWLPAGTILVHNDLYPFVSDSVATYFGDCITLPFDC 6927
Query 6898 KWDLIISDMYDPRTK---HVTKENDSKEGFFTYL-CGFIKQKLALGGSIAVKITEHSWNA 6953
+WDLIISDMYD HV + +Y+ C I+ KLALGGS+A+KITE SWNA
Sbjct 6928 QWDLIISDMYDLLLDIGVHVVR--------CSYIHCHMIRDKLALGGSVAIKITEFSWNA 6979
Query 6954 DLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIF 7005
+LYKLMG+F++WT F TN NASSSE FLIG NYLGKPK +IDG MHA F
Sbjct 6980 ELYKLMGYFAFWTVFCTNANASSSEGFLIGINYLGKPKVEIDGNVMHAIICF 7031
Score = 84.7 bits (208), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 51/155 (33%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPN--LNAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
GIF SL + T + QV + N++ ++ +
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLI 1427
Score = 67.4 bits (163), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 54/189 (29%), Positives = 90/189 (48%), Gaps = 17/189 (9%)
Query 822 KGVTFGED-TVWEVQGY-KNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEA 879
+ VTF E TV E+ K +++ +ELD+ + +LN C + V+ ++ EF VV +A
Sbjct 853 RCVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGEFEVDDTVDMEEFYAVVIDA 912
Query 880 VVKTLQPVSDLL---TNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDA 936
+ + L P +L + L + + +LFD+AGEE + ++YC+F P EDD
Sbjct 913 IEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLAPKLYCAFTAP----EDDD 968
Query 937 ECEEEEIDETCEHEYGTEDDYQGLPLEFGASAE-TVRVEEEEEEDWLDDTTEQSEIEPEP 995
EE ++E T+ L ++ E V E+EE + L+DT +
Sbjct 969 FLEESGVEEDDVEGEETD-------LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETS 1021
Query 996 EPTPEEPVN 1004
+ EE V
Sbjct 1022 DSQVEEDVQ 1030
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 4328 bits (11225), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2303/4963 (46%), Positives = 3160/4963 (64%), Gaps = 192/4963 (4%)
Query 2148 YVFTLLFQLCTFTKSTNSRIRASLPT---TIAKNSVKSVAKLCLDAGINYVKSPKFSKL- 2203
Y+F+LL K + ++ A +P I K SVK NY F +L
Sbjct 1984 YLFSLLAICFRALKKRDMKVMAGVPERTGIILKRSVK----------YNYKALKFFFRLK 2033
Query 2204 FTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSF 2263
F L S+ L +L + F + + G P C + Y NS+ D+C G+
Sbjct 2034 FQYIKVFLKFSLVLYTLYALMFMF-IRFTPVGTP-ICKRYTDGYANST-FDKNDYC-GNV 2089
Query 2264 PCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSA- 2322
C ICL G + L + I + L IL L +++ ++F FF +G++
Sbjct 2090 LCKICLYGYEELSDFTHTRVIWQHLKD-PLIGNILPLF--YLVFLIIFGGFFVRIGITYF 2146
Query 2323 IMQ-VFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGC 2381
IMQ + A + N WL+ + P ++M + + I H++ GC
Sbjct 2147 IMQYINAAGVALGYQDNVWLL-------HLLPFNSMGNIIVVAFIVTRILLFLKHVLFGC 2199
Query 2382 TSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTF 2441
+C+ C K + TRV TI+ G+ +SFYV ANGG+ FCK HN+ C++CD++ G TF
Sbjct 2200 DKPSCIACSKSAKLTRVPLQTILQGVTKSFYVNANGGKKFCKKHNFFCVDCDSYGYGCTF 2259
Query 2442 ISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNL 2501
I+D +A +LS K + PT ++ I+D V NG +LY K + +
Sbjct 2260 INDVIAPELSNVTKLNVIPTGPATIIIDKVEFSNGFYYLYSGSTFWKYNFDITEAKYACK 2319
Query 2502 DNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDST 2561
D L+ N + + +VF+ S + + K+A VY+SQL+C+PI L+D AL++ + +
Sbjct 2320 DVLKNCN----ILTDFVVFN-NSGSNVTQVKNACVYFSQLLCKPIKLVDSALLASL--NV 2372
Query 2562 EVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDT 2621
+ S + A+V+ S +F + + + R+ + +
Sbjct 2373 DFSANLHKAFVEVLSNSFGKDLSNCSNM----------------------NECRESLGLS 2410
Query 2622 DVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVE-NMTPRDLGACIDCNARHINAQV 2680
DV ++ + +H D+ ++ S NN +++Y K E + D+ C+ A+ +N V
Sbjct 2411 DVPEEEFSAAVSEAHRYDVLISDVSFNNLIVSYAKPEEKLAVHDIANCMRVGAKVVNHNV 2470
Query 2681 AKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGG 2740
NV ++W KD+++LSE+ RK I K I F LT R + + T ++ K G
Sbjct 2471 LTKDNVPVVWLAKDFIALSEEARKYIVRTTKTKGINFMLTFNDRRMHLTIPTISVANKKG 2530
Query 2741 KIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEI-IGYKAIQDGVTRDIIS 2799
+ + F + + L L+ + + L T++ +K I++GV +
Sbjct 2531 AGLPSLFTRLY--SFFWHLCVLIVVLFVATSLLDFSAQVTSDTQYDFKYIENGVLKVFEK 2588
Query 2800 TDDCFANKHAGFDAWFSQRGGSY-KNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDF 2858
DC N F+ W + + GS N + CP+V + E+ +I PG+P V + G
Sbjct 2589 PLDCVHNAFVNFNEWHNAKFGSIPTNSRRCPIVVGT-SDEVRYI-PGVPAGVF--LYGKS 2644
Query 2859 LHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEG 2918
L F +C+ L + +C+ + CT G+ V YCY +++
Sbjct 2645 LIFAMSTIFGTSGLCFDDRGLTD-----PDSCIFNSACTTLSGIGGRNV-YCYREGVVDN 2698
Query 2919 SISYSELRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDAEYCRHGTCERSEVGICLST 2977
+ YS L P + Y LMDG+ I P G +R + T YCR G C S+ G+C+
Sbjct 2699 AKLYSSLLPHSYYRLMDGNHIVLPEIITRGFGIRTIKTQAMTYCRTGECIDSQAGVCVGL 2758
Query 2978 SGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCA 3037
+V + S CG +L+ N+ + +S ++ ++A A
Sbjct 2759 DRFFVYSKT---PGSDYVCGTGFFSLLFNVIGMFSNSIPVTVMSGQILLNCVVAFTAVMA 2815
Query 3038 AYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYL-YLTFYF--T 3094
+ F KF+R+FG+ + V +S + +V S++ S+ L Y T YF T
Sbjct 2816 CFAFTKFKRLFGDMSFGV--------LSVGLCTVVNNLSYVVTQNSIGMLAYATLYFLCT 2867
Query 3095 NDV--SFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRV---MFNGVTF 3149
V S++ H+ + + + P+W+ Y+ C L+ F N + +V +F G F
Sbjct 2868 KGVRYSWVWHVGFAISYCFLAPWWVVLAYLICALLE----FLPNLFKLKVSTQLFEGDKF 2923
Query 3150 -STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAAC 3208
+FE AA TF+L+ Y KL + + + +Y A YN+YKY+SG+ YR A
Sbjct 2924 VGSFESAASGTFVLDMHSYQKLANS--ISTEKLKQYCASYNRYKYYSGSASEADYRLACF 2981
Query 3209 CHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLN 3268
HLAKA++DF+N D LY PP S S LQ+G RKMA PSG VEGC+V+V+ G TLN
Sbjct 2982 AHLAKAMSDFANDHMDKLYTPPTVSYNST-LQAGLRKMAQPSGIVEGCIVRVSYGNLTLN 3040
Query 3269 GLWLDDTVYCPRHVICT-AEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLL 3327
GLWL DTV CPRHVI + ++++ ++ L+R H+F + +GN+ L VI SM+ LL
Sbjct 3041 GLWLGDTVICPRHVIASNTTNVIDYDHAMSLVRL--HNFSISSGNMFLGVISASMRGTLL 3098
Query 3328 RLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGS 3387
+KV+ SN TP Y + ++PG +F++LACY+GS +GVY MR N+TI+GSF++G+CGS
Sbjct 3099 HIKVNQSNVNTPNYTYKVLKPGDSFNILACYDGSAAGVYGVNMRTNYTIRGSFISGACGS 3158
Query 3388 VGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAW 3447
G+NI+ V FCYMHH+EL +G H G+D++G YG + D+ T Q G +T NV +W
Sbjct 3159 PGYNINNGVVEFCYMHHLELGSGCHVGSDMDGTMYGKYEDQPTLQIEGASNLVTENVCSW 3218
Query 3448 LYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAA 3507
LY A+INGDRW+L+ + ++ +N A++ L +VD L A+TG+ V + A+
Sbjct 3219 LYGALINGDRWWLSSVSVGVDTYNEWALRNGMTALK--NVDCFSLLVAKTGVDVGRLLAS 3276
Query 3508 LKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ-GKFKKIVKGTHHWMLLTFLT 3566
+++L N G++ILG T L DEFT +VV+Q GVT Q GK + + L FL
Sbjct 3277 IQKLHGN-FGGKSILGCTSLCDEFTLSEVVKQMYGVTLQSGKVSRAFRNASIVCCLLFL- 3334
Query 3567 SLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAY 3626
L + S F++ P L I+ ++ MLLVKHK FL L+LLPSL V+
Sbjct 3335 ---FLSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLFLQLYLLPSLCIVSG 3391
Query 3627 FNMV--YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARR 3684
+N+ Y ++++ + G+ + + + ++ L T R + +
Sbjct 3392 YNIFKDYHFYTYMLEEFDY----KVPFGGFNVTGVLNISLCCFVMGLHTFR--FLQTPNK 3445
Query 3685 VWT-LMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYY 3743
+++ ++ V+T++Y YY + + L+++ S + T F+ A +
Sbjct 3446 IFSYVVAVLTVLYTYYY------STDVLGLILTSMSGF----TNYWFIGTATYKLATYVL 3495
Query 3744 P--LLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMN 3801
P L + + ++ ++ +Y LGYC C Y+G +NR+ +LTLG Y++ VS EF+YM
Sbjct 3496 PHTSLLDSFDAIKAVVFLYLLLGYCNCVYYGSLYWINRFCKLTLGCYEFKVSAAEFKYMV 3555
Query 3802 SQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESS 3861
+ GL P DA L++KL+G+GG+ IK+++VQSK++D+KCT+VVLL L + + ++
Sbjct 3556 ANGLRAPTGVFDALILSLKLIGVGGRKTIKISSVQSKLTDLKCTNVVLLGCLSNMNIAAN 3615
Query 3862 SKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAI 3921
S+ WA CV LHN I L D A E +++LL+ LS A ++ L + ++ + LQ++
Sbjct 3616 SREWAYCVDLHNKINLCNDAEAAQEMLLALLAFFLSKNSAFGVDELLDSYFNDSSVLQSV 3675
Query 3922 ASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKM 3981
A+ + +LPSY AY TA+++YE A+ANG ++K+L+ ++NVAKSEFDR+A+ QRKL++M
Sbjct 3676 AATYVNLPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFDREASTQRKLDRM 3735
Query 3982 ADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPL 4041
A+QA +QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I++ A+DG VPL+IIP
Sbjct 3736 AEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVPLSIIPA 3795
Query 4042 TTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAW 4101
+A KL +VV D +Y YA +W + + D D K V E+ N +LAW
Sbjct 3796 VSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTSNVESLAW 3855
Query 4102 PLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLAL 4161
PL + R +KLQNNE+ P ++Q A + D NAL Y+N G F+ A
Sbjct 3856 PLFLNCERI---IKLQNNEIIPSKIKQRPIKA-EGEGVVADGNAL--YSNEGGRTFMYAF 3909
Query 4162 LSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLG 4221
+SD DLK ++ G+ I ELEPPC+F+ + P GP VKYLYF++ LNNL RG VLG
Sbjct 3910 ISDKPDLKVVKWEFDGGSNAI--ELEPPCKFLVEAPSGPVVKYLYFVRNLNNLRRGAVLG 3967
Query 4222 SLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGT 4281
+ ATVRLQAG TE NS++L+ CAFAVDP K Y D + SG +P+ NCVKML +G
Sbjct 3968 FIGATVRLQAGKQTEQATNSSLLTLCAFAVDPPKTYLDAVKSGHRPVGNCVKMLANGSGN 4027
Query 4282 GQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFT 4341
GQAIT EA+ +Q+S+GGAS CLYCR H++HP+ GFC L+GKYVQ+P DP+ F
Sbjct 4028 GQAITNGVEASTNQDSYGGASVCLYCRAHVEHPDMDGFCKLRGKYVQVPLGTL-DPIRFV 4086
Query 4342 LRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVY 4401
L NTVC VCG W+ GC+CD+ ++QS D S +LNRV G SAARL P G+ T V+
Sbjct 4087 LENTVCKVCGCWQANGCTCDR---AVIQSVD-SGYLNRVRGSSAARLEPL-NGSDTHHVF 4141
Query 4402 RAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKD 4461
RAFD+YN VA +KFLK NC R + D+ D++++VK+ T S +HE++IYNL+ D
Sbjct 4142 RAFDVYNRDVACISKFLKVNCVRLKNLDKH----DAFWIVKKCTKSVMEHEQSIYNLISD 4197
Query 4462 CPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCC 4521
C AVA HDFF ++ + ++ RQ LT+YTM DL YALR+FDE NC+TLK+ILV C
Sbjct 4198 CGAVAKHDFFTWKEGRSVYGNVCRQDLTEYTMMDLCYALRNFDENNCETLKKILVVVGAC 4257
Query 4522 DDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDL 4581
D+ YF+ K W+D VEN D+ RVYA LG V +++LK V++CDAM + GIVGV+TLDNQDL
Sbjct 4258 DESYFDNKLWFDPVENEDVHRVYAKLGTIVARAMLKCVKYCDAMVEQGIVGVITLDNQDL 4317
Query 4582 NGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADL-AKPLIKWDLL 4640
NG++YDFGDFV G GVPI SYYS +MP++ +T LA+E + +D+ + +DLL
Sbjct 4318 NGDFYDFGDFVTSVKGMGVPICTSYYSYMMPVMGMTNCLASECFIKSDIFGEDFRTFDLL 4377
Query 4641 KYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVR 4700
YDFTE ++ LF++YFK+W QTYHPNC +C D+ CI+HCANFN LF+T P T+FGPL R
Sbjct 4378 AYDFTEHKVNLFNKYFKHWGQTYHPNCEDCHDESCIVHCANFNTLFATTIPITAFGPLCR 4437
Query 4701 KIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDK 4760
K ++DGVP V + GYHF++LG+V N+D+NLHSSRL+ ELL + ADP++ AS L+DK
Sbjct 4438 KCWIDGVPLVTTAGYHFKQLGIVWNKDLNLHSSRLTINELLQFCADPSLLIASSPALVDK 4497
Query 4761 RTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAIS 4820
RT CFSVAAL + QTVKPG+FN++FYDF S+GFF+EGS + LKHFFFAQ G+AA+
Sbjct 4498 RTVCFSVAALGTGMTNQTVKPGHFNREFYDFLRSQGFFEEGSELTLKHFFFAQKGDAAVR 4557
Query 4821 DYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGK 4880
D+DYYRYN T+ DI Q V ++V YF Y+GGCI A +VIVNNL+KSAG+PFNK+GK
Sbjct 4558 DFDYYRYNRTTVLDICQARVVYQIVQCYFGMYEGGCITAKEVIVNNLNKSAGYPFNKFGK 4617
Query 4881 ARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQF 4940
A LYYDS+SYE+QD L+AYTKRN+IPT+TQ+NLKYAIS K+RARTV GVS+ STMT RQ+
Sbjct 4618 AGLYYDSLSYEEQDDLYAYTKRNIIPTMTQLNLKYAISGKDRARTVGGVSLLSTMTTRQY 4677
Query 4941 HQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLR 5000
HQK LKSI TRGA+VVIGT+KFYGGW NMLKT+ DVE PHLMGWDYPKCDRA+PNM+R
Sbjct 4678 HQKHLKSIVNTRGASVVIGTTKFYGGWDNMLKTLIKDVENPHLMGWDYPKCDRALPNMIR 4737
Query 5001 IMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYAN 5060
++++++L KH CC+ S R+YRL NE AQVL+EMV G YVKPGGT+SGDATTAYAN
Sbjct 4738 MISAMILGSKHVNCCSSSDRYYRLCNELAQVLTEMVYSNGGFYVKPGGTTSGDATTAYAN 4797
Query 5061 SVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRK 5120
SVFNI QA +ANVN LLS D N + V+ LQ +LY+C YR+ VD FV+E++ YLRK
Sbjct 4798 SVFNIFQATSANVNRLLSVDSNTCNNIEVKQLQRKLYDCCYRSSSVDQSFVEEYFGYLRK 4857
Query 5121 HFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHE 5180
HFSMMILSDD VVCYNS YAA G VA + FKAVLYYQNNVFMS +KCW E D+ KGPHE
Sbjct 4858 HFSMMILSDDGVVCYNSEYAALGYVADLNAFKAVLYYQNNVFMSASKCWIEPDINKGPHE 4917
Query 5181 FCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTK 5240
FCSQHTM + D YLPYPDPSRIL AG FVDDIVKTD +++ER+VSLAIDAYPL+K
Sbjct 4918 FCSQHTMQIVDKDGTYYLPYPDPSRILSAGVFVDDIVKTDPVILLERYVSLAIDAYPLSK 4977
Query 5241 HPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVL 5300
H N EY VF + L +++ L+ L +LD +SV L D T+++W+ FY +MY +VL
Sbjct 4978 HDNPEYRRVFTVMLDWVKHLYKTLNQGVLDSFSVTLLEDATAKFWDESFYASMYEQSSVL 5037
Query 5301 QAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTD 5360
Q+ G CV+C+SQT LRCG CIRRP LC KC YDHV+STSHK +L++ PYVC + GC V+D
Sbjct 5038 QSAGLCVVCSSQTVLRCGDCIRRPMLCTKCAYDHVVSTSHKFILAITPYVCCSSGCGVSD 5097
Query 5361 VTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGD 5420
VT+LYLGG+SY+C HKP +SFPLC++G VFGLYKN+ GS +V DFN +AT DWT+ D
Sbjct 5098 VTKLYLGGLSYWCVDHKPRLSFPLCSSGNVFGLYKNSATGSPDVDDFNTLATSDWTDVKD 5157
Query 5421 YILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRN 5480
Y LAN + L+LFAAET+KA EE+ K SY AT+ EV+ +EL L WEVGKPRPPL+RN
Sbjct 5158 YKLANDVKDSLRLFAAETIKAKEESVKSSYACATIHEVVGPKELVLKWEVGKPRPPLSRN 5217
Query 5481 YVFTGYRVTKNSKVQIGEYTFEKGDY-GDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAP 5539
VFT Y +TKN+K Q+GE+TFEK DY DAV Y+ T T KL G FVLTSH V PL AP
Sbjct 5218 SVFTCYHITKNTKFQVGEFTFEKLDYDNDAVSYKSTATTKLVPGMVFVLTSHNVQPLRAP 5277
Query 5540 TLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALY 5599
T++ QE Y + L P NI +++S+ + YQ +G QK +T+QGPPG+GKSH IGL LY
Sbjct 5278 TIINQERYSTLHKLRPAFNIHEDYSNLIPYYQLIGKQKLTTIQGPPGSGKSHCVIGLGLY 5337
Query 5600 YPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFC 5659
+P ARIV+TACSHAAVD+LC KA D+CSRIIP +AR+EC+D FK N+T QY+F
Sbjct 5338 FPGARIVFTACSHAAVDSLCVKAATAYSSDRCSRIIPQKARIECYDGFKSNNTSAQYLFS 5397
Query 5660 TVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLE 5719
TVNALPE ADI V DE+SM TNYDLSV+N R+ +H VY+GDP QLPAPR ++T+G L
Sbjct 5398 TVNALPEVNADICVVDEVSMCTNYDLSVINQRVNYRHIVYVGDPQQLPAPRVMITRGVLV 5457
Query 5720 PEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKG 5779
PE +N V R M + PD+FL C RCPAEIV+TVS +VY+N+ K +S +CFK++ +G
Sbjct 5458 PEDYNVVTRRMCVLKPDIFLHKCYRCPAEIVNTVSEMVYENQFVPVKSESKECFKIYCRG 5517
Query 5780 VITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQG 5839
+ D S+INR Q+ VVR FL +NP W KAVFISPYNSQN VA ++LGL QTVDSSQG
Sbjct 5518 NVQVDNGSSINRRQLEVVRMFLAKNPKWAKAVFISPYNSQNYVAGRVLGLQIQTVDSSQG 5577
Query 5840 SEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVA 5899
SEYDYVI+TQT++TAH+ NVNRFNVAITRAK GILCIM DR+L+D L+F L++ +
Sbjct 5578 SEYDYVIYTQTSDTAHASNVNRFNVAITRAKKGILCIMCDRELFDILKFYELKL-----S 5632
Query 5900 TLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTE-GLCVDIPGIPKDMTYRRLIS 5958
LQ + GLFKDC K L P+ APT +S+ FKT+ L V I G+ + Y +IS
Sbjct 5633 DLQVGDGCGLFKDCYKGEDNLPPSHAPTFMSLSDNFKTDKDLAVQI-GVNGPVKYEHVIS 5691
Query 5959 MMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVN 6018
MGF+ + V +F TR+ A+R+ R W+GFDVEG H VGTN+PLQLGFS GV+
Sbjct 5692 FMGFRFDINVPNQHTLFCTRDFAMRNARGWLGFDVEGAHVIGSNVGTNVPLQLGFSNGVD 5751
Query 6019 LVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKG 6078
V P G V TE V A+ PPGDQF HL+PL+ KG PW+V+R +IVQM SD L
Sbjct 5752 FVVRPEGCVSTEVGDVIQPVRARAPPGDQFTHLLPLLRKGQPWSVIRRRIVQMCSDYLAN 5811
Query 6079 LSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYV 6138
LSD ++FVLW+ G ELT+M+YFVK+GP +T C C KRATC+++++ T++C+ H++G DY+
Sbjct 5812 LSDTLIFVLWSGGLELTTMRYFVKLGPVQT-CDCGKRATCYNSTNHTFSCFRHALGSDYI 5870
Query 6139 YNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEY 6198
YN + ID+QQWG+TG+L NH + C +H N HVAS DA MTRCLA+H+CFVK VDWS+ Y
Sbjct 5871 YNCYCIDIQQWGYTGSLSMNHHEVCNIHRNEHVASGDAAMTRCLAIHDCFVKNVDWSITY 5930
Query 6199 PIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPC 6258
P I +E +N + R VQ V+++ L +HD+GNPK I+CV + W YD P
Sbjct 5931 PFIANEQAINKSGRLVQSHVMRAVLKLYNPKAIHDVGNPKGIRCV-VTDASWYCYDKNPT 5989
Query 6259 SDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDG 6318
+ +E Y Y TH DG+CLFWNCNVD YP ++VCRFDTR+ S LNL GC+G
Sbjct 5990 NTNVKMLE---YDYITHGQ--LDGLCLFWNCNVDMYPEFSVVCRFDTRMRSTLNLEGCNG 6044
Query 6319 GSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITR 6378
GSLYVN HAFHTPA+DK AF LK +PFF+Y DS CE ++ ++YVPL+++ CITR
Sbjct 6045 GSLYVNNHAFHTPAYDKRAFAKLKAMPFFFYDDSECE----KLQDAVNYVPLRASNCITR 6100
Query 6379 CNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTF--TRLQSLENVAY 6436
CN+GGAVC H Y Y+ AYN +AGF++W+ FD +NLW TF + +Q LEN+AY
Sbjct 6101 CNVGGAVCSKHCALYHNYVMAYNTFTTAGFTIWVPNSFDMFNLWQTFKNSNVQGLENIAY 6160
Query 6437 NVVNKGHFDGHAGEAPVSIINNAVYTKVDGI-DVEIFENKTTLPVNVAFELWAKRNIKPV 6495
NVV KG F G GE PV+++N+ V + DG+ D +F N T+LP NVAFEL+AKR +
Sbjct 6161 NVVKKGSFVGVEGELPVAVVNDKVMVR-DGVSDNVVFVNNTSLPTNVAFELYAKRKVGLT 6219
Query 6496 PEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGR 6555
P + IL NLGV + V+WDY+ P T VC TD + LFD
Sbjct 6220 PPLTILKNLGVVCTSKCVLWDYEASRPLTTFTKDVCKYTDFD--------GDVCTLFDNS 6271
Query 6556 VEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVK--TQFNYFKKVDG 6613
V G + F +N VLI+ +VK LT K +NGV + K T + Y +K DG
Sbjct 6272 VPGAFERFTVTKNAVLISLTAVKKLTAIK-LTYGYLNGVPVFTHEDKPFTWYIYTRK-DG 6329
Query 6614 IIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQ 6673
+ P+ YFTQ R + DF+PRS ME DFL + M FI +Y LE Y FEH+V+GD S
Sbjct 6330 AFVEYPDGYFTQGRVISDFQPRSNMEEDFLNMDMGLFISKYGLEDYGFEHVVFGDVSKTT 6389
Query 6674 LGGLHLMIGLAKRSQDSPLKLEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFV 6732
LGGLHL+I + S+ LK+EDF+ DST+K+ +T SSK VC+ +DLLLDDFV
Sbjct 6390 LGGLHLLISQIRLSKIGVLKVEDFVSSSDSTLKSCTVTYVDNPSSKMVCTYVDLLLDDFV 6449
Query 6733 EIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKM 6792
I+KS DLSV+SKV +V ID +MLWCKD V+TFYP+LQ+++ W+ G +MP++YK+
Sbjct 6450 NILKSVDLSVVSKVHEVVIDCKVWRWMLWCKDHKVQTFYPQLQSAE-WKCGYSMPSIYKI 6508
Query 6793 QRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKG 6852
QRM LE C+L NYG +P GIM NV KYTQLCQYLN+ T+ VP++MRV+H GAGSDKG
Sbjct 6509 QRMCLEPCNLYNYGSGLKLPDGIMFNVVKYTQLCQYLNSTTMCVPHHMRVLHLGAGSDKG 6568
Query 6853 VAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTK 6912
VAPGTAVLR+WLP ++VD+D+ND+VSDAD + GDCA+++ +K+DL+ISDMYD RTK
Sbjct 6569 VAPGTAVLRRWLPLDAVIVDNDVNDYVSDADFSYTGDCASMYLTDKFDLVISDMYDGRTK 6628
Query 6913 HVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNV 6972
+N SKEGFF Y+ G I +KLALGG++A+KITE SWN LY+L+ F +WT F T+V
Sbjct 6629 SCDGDNVSKEGFFPYINGVITEKLALGGTVAIKITEFSWNKKLYELIQKFEYWTLFCTSV 6688
Query 6973 NASSSEAFLIGANYLG--KPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLR 7030
N SSSEAFLIG ++LG IDG MHANYIFWRN+ + +S S+ D+SKF K +
Sbjct 6689 NTSSSEAFLIGVHFLGDFSTNAIIDGNIMHANYIFWRNSTIMTMSYNSVLDLSKFSCKHK 6748
Query 7031 GTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
T V++LK++ + D++ LL+ G+L+IR N V S+ LVN+
Sbjct 6749 ATVVVNLKDSSVTDLVLGLLKNGKLLIRNNGVVCGFSNHLVNS 6791
Score = 70.5 bits (171), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 46/123 (37%), Positives = 60/123 (49%), Gaps = 2/123 (2%)
Query 1029 SANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL 1088
S N +VNAAN L HGGG+A AL+ T G +Q S+ Y+ NG + VG L+
Sbjct 1317 SVNHDFVVNAANEQLSHGGGIAKALDDLTKGELQVLSNQYVSRNGSIKVGSGVLIKCKE- 1375
Query 1089 AKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVR 1148
L+VVGP L KA F + + L PLLS GIF +SL + V
Sbjct 1376 -HSILNVVGPRKGKHAAELLTKAYTFVFKQKGVPLMPLLSVGIFKVPITESLAAFLACVG 1434
Query 1149 TQV 1151
+V
Sbjct 1435 DRV 1437
Score = 67.0 bits (162), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 77/317 (24%), Positives = 124/317 (39%), Gaps = 29/317 (9%)
Query 1538 SLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFV 1597
+L E K ++V T D + HT + S TYGQQ G ++ VT +KP + + V
Sbjct 1634 TLFEAKPVQVVVTQDQRSFHTVELSTSQTYGQQLGDCVVEDKKVTNLKPVSKDKVVS--V 1691
Query 1598 LPSDDTLRSEAF---EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLS 1654
+P+ D + F +HTLD + + +N G ++ +DNNC+++
Sbjct 1692 VPNVDWDKHYGFVDAGIFHTLDHTMFVFDNNVVN-----------GKRVLRTSDNNCWIN 1740
Query 1655 SVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQ 1714
+V L LQ KF LQ+ + GD A F + + GE D T+ + +
Sbjct 1741 AVCLQLQFANAKFKPKGLQQLWESYCTGDVAMFVHWLYWITGVEKGEPSDAENTLNIISR 1800
Query 1715 HANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIP-CVCGRDATQY 1773
+ + +L C +T + V+ ++ LK G+ CV G
Sbjct 1801 FLKPQGSVEMLRATSTTCDGTCST----KRVVSTPVVNASVLKVGLDDGNCVHGLPLVDR 1856
Query 1774 LVQQESSFVMMSA---PPAEYKLQQGTFLCANEYT----GNYQCGHYTHITAKETLYRID 1826
+V + ++ + P + L YT GHYT + KE D
Sbjct 1857 VVSVNGTVIITNVGDTPGKPVVATENLLLDGVSYTVFQDSTTGVGHYT-VFDKEAKLMFD 1915
Query 1827 GAHLTKMSEYKGPVTDV 1843
G L PVT V
Sbjct 1916 GDVLKPCDLNVSPVTSV 1932
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 4295 bits (11140), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2274/4892 (46%), Positives = 3088/4892 (63%), Gaps = 205/4892 (4%)
Query 2229 VLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETI---- 2284
+ + G+P C+ V Y NSS ++C S C +CL G L + + +
Sbjct 2044 IRFTPIGSP-VCDDVVAGYANSS-FDKNEYCN-SVICKVCLYGYQELSDFSHTQVVWQHL 2100
Query 2285 ------QVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISN 2338
V Y L I G +V A L+ F YL L VF G S
Sbjct 2101 RDPLIGNVMPFFYLAFLAIFG--GVYVKAITLYFIFQYLNSLG----VFLGLQQS----- 2149
Query 2339 SWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRV 2398
+WF+ Q+ P + F + H+ GC ++C+ C K R RV
Sbjct 2150 ---IWFL----QLVPFDVFGDEIVVFFIVTRVLMFIKHVCLGCDKASCVACSKSARLKRV 2202
Query 2399 ECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPI 2458
TI G +SFYV+ANGG FCK HN+ CLNCD++ G TFI+D +A ++ K +
Sbjct 2203 PVQTIFQGTSKSFYVHANGGSKFCKKHNFFCLNCDSYGPGCTFINDVIATEVGNVVKLNV 2262
Query 2459 NPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVI 2518
PT ++ ++D V NG +LY K S + + L+ S+ + I
Sbjct 2263 QPTGPATILIDKVEFSNGFYYLYSGDTFWKYNFDITDSKYTCKEALK----NCSIITDFI 2318
Query 2519 VFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSAT 2578
VF+ + + K+A VY+SQ++C+P+ L+D AL++ + S + + A+V S +
Sbjct 2319 VFNNNGS-NVNQVKNACVYFSQMLCKPVKLVDSALLASL--SVDFGASLHSAFVSVLSNS 2375
Query 2579 FSVPMEKLKALVATAHSELAKGVALDGV-LSTFVSAARQGVVDTDVDTKDVIECLKLSHH 2637
F + + + + D V L TF +A + +H
Sbjct 2376 FGKDLSSCNDM-----QDCKSTLGFDDVPLDTFNAAVAE------------------AHR 2412
Query 2638 SDLEVTGDSCNNFMLTYNKVENMTP-RDLGACIDCNARHINAQVAKSHNVSLIWNVKDYM 2696
D+ +T S NNF +Y K E P D+ C+ A+ +N V ++ ++W V+D++
Sbjct 2413 YDVLLTDMSFNNFTTSYAKPEEKFPVHDIATCMRVGAKIVNHNVLVKDSIPVVWLVRDFI 2472
Query 2697 SLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLL 2756
+LSE+ RK I K I F LT R + T I+ K G + + K+ L
Sbjct 2473 ALSEETRKYIIRTTKVKGITFMLTFNDCRMHTTIPTVCIANKKGAGLPSFSKVKKFFWFL 2532
Query 2757 CVLAALVCYIVMPVHTLSIHDGYT----NEIIGYKAIQDGVTRDIISTDDCFANKHAGFD 2812
C+ +IV LS D T + +K I+ G + + C N FD
Sbjct 2533 CL------FIVAAFFALSFLDFSTQVSSDSDYDFKYIESGQLKTFDNPLSCVHNVFINFD 2586
Query 2813 AWFSQRGG-SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGN 2871
W + G + N+ SCP+V + + VPG+P V A G L F
Sbjct 2587 QWHDAKFGFTPVNNPSCPIVVGV--SDEARTVPGIPAGVYLA--GKTLVFAINTIFGTSG 2642
Query 2872 ICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRY 2931
+C+ S + + AC+ + CT +G YCY L+EG+ YSEL P + Y
Sbjct 2643 LCFDASGVAD-----KGACIFNSACTTLS-GLGGTAVYCYKNGLVEGAKLYSELAPHSYY 2696
Query 2932 VLMDGSIIQFPNTYLEG-SVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRA 2990
++DG+ + P G +R + T YCR G C +S G+C +V N E +
Sbjct 2697 KMVDGNAVSLPEIISRGFGIRTIRTKAMTYCRVGQCVQSAEGVCFGADRFFVYNAE---S 2753
Query 2991 LSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGE 3050
S CG L+ N+ + + V +S ++ IIA + + F KF+R+FG+
Sbjct 2754 GSDFVCGTGLFTLLMNVISVFSKTVPVTVLSGQILFNCIIAFVAVAVCFLFTKFKRMFGD 2813
Query 3051 YN-HVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYF--TNDVSFLA--HLQW 3105
+ V A L + + + L Y T YF T V ++ HL +
Sbjct 2814 MSVGVFTVGACTLLNNVSYIVTQNTLGMLG--------YATLYFLCTKGVRYMWIWHLGF 2865
Query 3106 FAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRV---MFNGVTF-STFEEAALCTFL 3161
+ I P+W+ +Y F + F N + +V +F G F +FE AA TF+
Sbjct 2866 LISYILIAPWWVLMVYAFSAIFE----FMPNLFKLKVSTQLFEGDKFVGSFENAAAGTFV 2921
Query 3162 LNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNS 3221
L+ Y +L + + + +Y + YNKYKY+SG+ YR A HLAKA+ D++++
Sbjct 2922 LDMHAYERLANS--ISTEKLRQYASTYNKYKYYSGSASEADYRLACFAHLAKAMMDYASN 2979
Query 3222 GADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRH 3281
D LY PP S S LQ+G RKMA PSG VE C+V+V G LNGLWL D V CPRH
Sbjct 2980 HNDTLYTPPTVSYNST-LQAGLRKMAQPSGVVEKCIVRVCYGNMALNGLWLGDIVMCPRH 3038
Query 3282 VICTAE-DMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPK 3340
VI ++ ++ +Y ++R H+F + +GNV L V+ +M+ LL++KV+ +N TPK
Sbjct 3039 VIASSTTSTIDYDYALSVLRL--HNFSISSGNVFLGVVSATMRGALLQIKVNQNNVHTPK 3096
Query 3341 YKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFC 3400
Y + ++PG++F++LACY+G+ +GVY MR N+TI+GSF+NG+CGS G+NI+ V FC
Sbjct 3097 YTYRTVRPGESFNILACYDGAAAGVYGVNMRSNYTIRGSFINGACGSPGYNINNGTVEFC 3156
Query 3401 YMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFL 3460
Y+H +EL +G H G+DL+G YG + D+ T Q G + T NVLA+LYAA+ING W+L
Sbjct 3157 YLHQLELGSGCHVGSDLDGVMYGGYEDQPTLQVEGASSLFTENVLAFLYAALINGSTWWL 3216
Query 3461 NRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRT 3520
+ ++ FN A+ T + D L+A+TG+ V + A+++ L +N G+
Sbjct 3217 SSSRIAVDRFNEWAVHNGMT--TVGNTDCFSILAAKTGVDVQRLLASIQSLHKN-FGGKQ 3273
Query 3521 ILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWML----LTFLTSLLILVQSTQ 3576
ILG T L DEFT +VVRQ GV QG + + + + +L LTF S L+
Sbjct 3274 ILGHTSLTDEFTTGEVVRQMYGVNLQGGY--VSRACRNVLLVGSFLTFFWSELV-----S 3326
Query 3577 WSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASW 3636
++ FF+V P + +++ M +KHK F +FL+P+L + N+ +
Sbjct 3327 YTKFFWVNPGYVTPMFACLSLLSSLLMFTLKHKTLFFQVFLIPALIVTSCINLAF----- 3381
Query 3637 VMRIMTWLELAD-----TSLSGYRLKDCVMYASALVLLILMTART--VYDDAARRVWTLM 3689
+ + LA+ SL G+ + V V+ IL T ++ A V ++
Sbjct 3382 --DVEVYNYLAEHFDYHVSLMGFNAQGLVNIFVCFVVTILHGTYTWRFFNTPASSVTYVV 3439
Query 3690 NVITLVYKVYYG-NALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFI 3748
++T Y +Y + L A++++A SVT N+ V + + + V++ + + + I
Sbjct 3440 ALLTAAYNYFYASDILSCAMTLFA---SVTGNW--FVGAVCY--KVAVYMALRFPTFVAI 3492
Query 3749 TGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPP 3808
G+ ++ +M Y LGY CC++G+ NR+F++++GVYDY VS EF+YM + GL P
Sbjct 3493 FGD-IKSVMFCYLVLGYFTCCFYGILYWFNRFFKVSVGVYDYTVSAAEFKYMVANGLRAP 3551
Query 3809 KSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQC 3868
++D+ L+ KL+GIGG+ IK+++VQSK++D+KC++VVLL L + V ++S WA C
Sbjct 3552 TGTLDSLLLSAKLIGIGGERNIKISSVQSKLTDIKCSNVVLLGCLSSMNVSANSTEWAYC 3611
Query 3869 VQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSL 3928
V LHN I L D +A E +++LL+ LS A ++ L E ++ + LQ++AS + L
Sbjct 3612 VDLHNKINLCNDPEKAQEMLLALLAFFLSKNSAFGLDDLLESYFNDNSMLQSVASTYVGL 3671
Query 3929 PSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQ 3988
PSY Y A++ YE AV NG ++K+L+ ++NVAKSEFDR+A+ QRKL++MA+QA Q
Sbjct 3672 PSYVIYENARQQYEDAVNNGSPPQLVKQLRHAMNVAKSEFDREASTQRKLDRMAEQAAAQ 3731
Query 3989 MYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLM 4048
MYK+AR+ ++++KV SAM ++LF MLR+LD +++ I+N A+DG VPL++IP +A KL
Sbjct 3732 MYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNLAKDGVVPLSVIPAVSATKLN 3791
Query 4049 VVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTAL 4108
+V D +Y YA +W I + D D K+V + E+ N+ +L+WPL++
Sbjct 3792 IVTSDIDSYNRIQREGCVHYAGTIWNIIDIKDNDGKVVHVKEVTAQNAESLSWPLVLGCE 3851
Query 4109 RANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDL 4168
R VKLQNNE+ P L+Q S A A YNN G F+ A +SD DL
Sbjct 3852 RI---VKLQNNEIIPGKLKQRSIKAEGDGIV---GEGKALYNNEGGRTFMYAFISDKPDL 3905
Query 4169 KWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVR 4228
+ ++ G TI ELEPP +F+ D+P G ++KYLYF++ LN L RG VLG + ATVR
Sbjct 3906 RVVKWEFDGGCNTI--ELEPPRKFLVDSPNGAQIKYLYFVRNLNTLRRGAVLGYIGATVR 3963
Query 4229 LQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVT 4288
LQAG TE NS++L+ CAFAVDPAK Y D + SG +P+ NCVKML +G GQA+T
Sbjct 3964 LQAGKQTEQAINSSLLTLCAFAVDPAKTYIDAVKSGHKPVGNCVKMLANGSGNGQAVTNG 4023
Query 4289 PEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCT 4348
EA+ +Q+S+GGAS CLYCR H++HP+ GFC LKGKYVQ+P DP+ F L N VC
Sbjct 4024 VEASTNQDSYGGASVCLYCRAHVEHPSMDGFCRLKGKYVQVPLGTV-DPIRFVLENDVCK 4082
Query 4349 VCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYN 4408
VCG W GC+CD+ +MQS D + +LNRV G SAARL PC GT T VYRAFDIYN
Sbjct 4083 VCGCWLSNGCTCDR---SIMQSTDMA-YLNRVRGSSAARLEPC-NGTDTQHVYRAFDIYN 4137
Query 4409 EKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVH 4468
+ VA KFLK NC R + D+ D+++VVKR T S +HE++IY+ ++ C A+A H
Sbjct 4138 KDVACLGKFLKVNCVRLKNLDKH----DAFYVVKRCTKSAMEHEQSIYSRLEKCGAIAEH 4193
Query 4469 DFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNK 4528
DFF ++ + ++ R+ LT+YTM DL YALR+FDE NCD LK IL+ C++ YFN
Sbjct 4194 DFFTWKDGRAIYGNVCRKDLTEYTMMDLCYALRNFDENNCDVLKSILIKVGACEESYFNN 4253
Query 4529 KDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDF 4588
K W+D VEN DI RVYA LG V +++LK V+FCDAM + GIVGV+TLDNQDLNG++YDF
Sbjct 4254 KVWFDPVENEDIHRVYALLGTIVARAMLKCVKFCDAMVEQGIVGVVTLDNQDLNGDFYDF 4313
Query 4589 GDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADL-AKPLIKWDLLKYDFTEE 4647
GDF G GVPI SYYS +MP++ +T LA+E + +D+ + +DLL+YDFTE
Sbjct 4314 GDFTCSIKGMGVPICTSYYSYMMPVMGMTNCLASECFVKSDIFGEDFKSYDLLEYDFTEH 4373
Query 4648 RLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGV 4707
+ LF++YFKYW YHPNC++C D++CI+HCANFN LFST P T+FGPL RK ++DGV
Sbjct 4374 KTALFNKYFKYWGLQYHPNCVDCSDEQCIVHCANFNTLFSTTIPITAFGPLCRKCWIDGV 4433
Query 4708 PFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSV 4767
P V + GYHF++LG+V N D+NLHSSRLS ELL + +DPA+ AS L+D+RT CFSV
Sbjct 4434 PLVTTAGYHFKQLGIVWNNDLNLHSSRLSINELLQFCSDPALLIASSPALVDQRTVCFSV 4493
Query 4768 AALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRY 4827
AAL + QTVKPG+FNK+FYDF + +GFF EGS + LKHFFFAQ +AA+ D+DYYRY
Sbjct 4494 AALGTGMTNQTVKPGHFNKEFYDFLLEQGFFSEGSELTLKHFFFAQKVDAAVKDFDYYRY 4553
Query 4828 NLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDS 4887
N PT+ DI Q V ++V +YFD Y+GGCI A +V+V NL+KSAG+P NK+GKA LYY+S
Sbjct 4554 NRPTVLDICQARVVYQIVQRYFDIYEGGCITAKEVVVTNLNKSAGYPLNKFGKAGLYYES 4613
Query 4888 MSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKS 4947
+SYE+QD L+AYTKRN++PT+TQ+NLKYAIS K RARTV GVS+ STMT RQ+HQK LKS
Sbjct 4614 LSYEEQDELYAYTKRNILPTMTQLNLKYAISGKERARTVGGVSLLSTMTTRQYHQKHLKS 4673
Query 4948 IAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVL 5007
I TRGA+VVIGT+KFYGGW NMLK + VE P LMGWDYPKCDRA+PNM+R++++++L
Sbjct 4674 IVNTRGASVVIGTTKFYGGWDNMLKNLIDGVENPCLMGWDYPKCDRALPNMIRMISAMIL 4733
Query 5008 ARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQ 5067
KH TCC+ + RF+RL NE AQVL+E+V G Y+KPGGT+SGDATTAYANSVFNI Q
Sbjct 4734 GSKHTTCCSSTDRFFRLCNELAQVLTEVVYSNGGFYLKPGGTTSGDATTAYANSVFNIFQ 4793
Query 5068 AVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMIL 5127
AV+ANVN LLS D N + V+ LQ +LYEC YR+ VD +FV E+Y YLRKHFSMMIL
Sbjct 4794 AVSANVNKLLSVDSNVCHNLEVKQLQRKLYECCYRSTIVDDQFVVEYYGYLRKHFSMMIL 4853
Query 5128 SDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTM 5187
SDD VVCYN++YA+ G VA + FKAVLYYQNNVFMS +KCW E D+ KGPHEFCSQHTM
Sbjct 4854 SDDGVVCYNNDYASLGYVADLNAFKAVLYYQNNVFMSASKCWIEPDINKGPHEFCSQHTM 4913
Query 5188 LVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYA 5247
+ + YLPYPDPSRIL AG FVDD+VKTD +++ER+VSLAIDAYPL+KH N EY
Sbjct 4914 QIVDKEGTYYLPYPDPSRILSAGVFVDDVVKTDAVVLLERYVSLAIDAYPLSKHENPEYK 4973
Query 5248 DVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACV 5307
VF++ L +++ L+ L +L+ +SV L D+T+++W+ FY MY VLQ+ G CV
Sbjct 4974 KVFYVLLDWVKHLYKTLNAGVLESFSVTLLEDSTAKFWDESFYANMYEKSAVLQSAGLCV 5033
Query 5308 LCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLG 5367
+C SQT LRCG C+RRP LC KC YDHVI T+HK +L++ PYVC A C V DVT+LYLG
Sbjct 5034 VCGSQTVLRCGDCLRRPMLCTKCAYDHVIGTTHKFILAITPYVCCASDCGVNDVTKLYLG 5093
Query 5368 GMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTC 5427
G+SY+C HKP ++FPLC+ G VFGLYKN+ GS +V DFN IAT DWT+ DY LAN
Sbjct 5094 GLSYWCHEHKPRLAFPLCSAGNVFGLYKNSATGSPDVEDFNRIATSDWTDVSDYRLANDV 5153
Query 5428 TERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYR 5487
+ L+LFAAET+KA EE+ K SY AT+ EV+ +EL L WEVG+P+PPLNRN VFT Y
Sbjct 5154 KDSLRLFAAETIKAKEESVKSSYACATLHEVVGPKELLLKWEVGRPKPPLNRNSVFTCYH 5213
Query 5488 VTKNSKVQIGEYTFEKGDY-GDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEH 5546
+TKN+K QIGE+ FEK +Y DAV Y+ T T KL G FVLTSH V PL APT+ QE
Sbjct 5214 ITKNTKFQIGEFVFEKAEYDNDAVTYKTTATTKLVPGMVFVLTSHNVQPLRAPTIANQER 5273
Query 5547 YVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIV 5606
Y I L+P NI + +SS V YQ +G QK +T+QGPPG+GKSH IGL LYYP ARIV
Sbjct 5274 YSTIHKLHPAFNIPEAYSSLVPYYQLIGKQKITTIQGPPGSGKSHCVIGLGLYYPGARIV 5333
Query 5607 YTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPE 5666
+TACSHAAVD+LC KA DKCSRIIP RARVEC+D FK N+T QY+F TVNALPE
Sbjct 5334 FTACSHAAVDSLCVKASTAYSNDKCSRIIPQRARVECYDGFKSNNTSAQYLFSTVNALPE 5393
Query 5667 TTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5726
ADIVV DE+SM TNYDLSV+N R+ +H VY+GDP QLPAPR ++++GTLEP+ +N V
Sbjct 5394 CNADIVVVDEVSMCTNYDLSVINQRISYRHVVYVGDPQQLPAPRVMISRGTLEPKDYNVV 5453
Query 5727 CRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVS 5786
+ M + PD+FL C RCPAEIV TVS +VY+N+ S QCFK+F KG + D
Sbjct 5454 TQRMCALKPDVFLHKCYRCPAEIVRTVSEMVYENQFIPVHPDSKQCFKIFCKGNVQVDNG 5513
Query 5787 SAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVI 5846
S+INR Q+ VVR FL +NP W KAVFISPYNSQN VAS++LGL QTVDSSQGSEYDYVI
Sbjct 5514 SSINRRQLDVVRMFLAKNPRWSKAVFISPYNSQNYVASRLLGLQIQTVDSSQGSEYDYVI 5573
Query 5847 FTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENV 5906
+ QT++TAH+ NVNRFNVAITRAK GILCIM DR L+D L+F L++ + LQA
Sbjct 5574 YAQTSDTAHASNVNRFNVAITRAKKGILCIMCDRSLFDLLKFFELKL-----SDLQANEG 5628
Query 5907 TGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNY 5966
GLFKDCS+ L P+ A T +S+ FKT+ G+ + Y +IS MGF+ +
Sbjct 5629 CGLFKDCSRGDDLLPPSHANTFMSLADNFKTDQYLAVQIGVNGPIKYEHVISFMGFRFDI 5688
Query 5967 QVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGY 6026
+ + +F TR+ A+R+VR W+GFDVEG H VGTN+PLQLGFS GV+ V P G
Sbjct 5689 NIPNHHTLFCTRDFAMRNVRGWLGFDVEGAHVVGSNVGTNVPLQLGFSNGVDFVVRPEGC 5748
Query 6027 VDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFV 6086
V TE+ V A+ PPG+QF HL+PL+ +G PW+VVR +IVQM SD L LSD ++FV
Sbjct 5749 VVTESGDYIKPVRARAPPGEQFAHLLPLLKRGQPWDVVRKRIVQMCSDYLANLSDILIFV 5808
Query 6087 LWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDV 6146
LWA G ELT+M+YFVKIGP ++ C C K ATC++++ TY C+ H++G DY+YNP+ ID+
Sbjct 5809 LWAGGLELTTMRYFVKIGPSKS-CDCGKVATCYNSALHTYCCFKHALGCDYLYNPYCIDI 5867
Query 6147 QQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELR 6206
QQWG+ G+L NH +HC VH N HVAS DAIMTRCLA+H+CFVK VDWS+ YP IG+E
Sbjct 5868 QQWGYKGSLSLNHHEHCNVHRNEHVASGDAIMTRCLAIHDCFVKNVDWSITYPFIGNEAV 5927
Query 6207 VNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIE 6266
+N + R VQ ++S L ++DIGNPK I+C + +W +D P + +E
Sbjct 5928 INKSGRIVQSHTMRSVLKLYNPKAIYDIGNPKGIRCA-VTDAKWFCFDKNPTNSNVKTLE 5986
Query 6267 ELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKH 6326
Y Y TH DG+CLFWNCNVD YP ++VCRFDTR S LNL GC+GGSLYVN H
Sbjct 5987 ---YDYITHGQ--FDGLCLFWNCNVDMYPEFSVVCRFDTRCRSPLNLEGCNGGSLYVNNH 6041
Query 6327 AFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVC 6386
AFHTPAFDK AF LK +PFF+Y D+ C+ ++ I+YVPL+++ CIT+CN+GGAVC
Sbjct 6042 AFHTPAFDKRAFAKLKPMPFFFYDDTECD----KLQDSINYVPLRASNCITKCNVGGAVC 6097
Query 6387 RHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFT-RLQSLENVAYNVVNKGHFD 6445
H Y Y++AYN SAGF++W+ FDTYNLW TF+ LQ LEN+A+NV+ KG F
Sbjct 6098 SKHCAMYHSYVNAYNTFTSAGFTIWVPTSFDTYNLWQTFSNNLQGLENIAFNVLKKGSFV 6157
Query 6446 GHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLG 6505
G GE PV+++N+ V + +D +F NKT+LP NVAFEL+AKR + P I IL NLG
Sbjct 6158 GDEGELPVAVVNDKVLVRDGTVDTLVFTNKTSLPTNVAFELYAKRKVGLTPPITILRNLG 6217
Query 6506 VDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRN 6565
V + VIWDY+ E P T VC TD + LFD + G ++ F
Sbjct 6218 VVCTSKCVIWDYEAERPLTTFTKDVCKYTDFE--------GDVCTLFDNSIVGSLERFSM 6269
Query 6566 ARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVK--TQFNYFKKVDGIIQQLPETYF 6623
+N VL++ +VK LT K +NGV + K T + Y +K +G + P+ YF
Sbjct 6270 TQNAVLMSLTAVKKLTGIK-LTYGYLNGVPVNTHEDKPFTWYIYTRK-NGKFEDYPDGYF 6327
Query 6624 TQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGL 6683
TQ R DF PRS ME DFL + M FI +Y LE Y FEH+VYGD S LGGLHL+I
Sbjct 6328 TQGRTTADFSPRSDMEKDFLSMDMGLFINKYGLEDYGFEHVVYGDVSKTTLGGLHLLISQ 6387
Query 6684 AKRSQDSPLKLEDFIPM-DSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV 6742
+ + LK+++F+ DST+K+ +T A SSK VC+ +DLLLDDFV I+KS DLSV
Sbjct 6388 VRLACMGVLKIDEFVSSNDSTLKSCTVTYADNPSSKMVCTYMDLLLDDFVSILKSLDLSV 6447
Query 6743 ISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDL 6802
+SKV +V +D +MLWCKD ++TFYP+LQAS+ W+ G +MP++YK+QRM LE C+L
Sbjct 6448 VSKVHEVMVDCKMWRWMLWCKDHKLQTFYPQLQASE-WKCGYSMPSIYKIQRMCLEPCNL 6506
Query 6803 QNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQ 6862
NYG +P GIM NV KYTQLCQYLN+ T+ VP++MRV+H GAGSDKGVAPGTAVLR+
Sbjct 6507 YNYGAGVKLPDGIMFNVVKYTQLCQYLNSTTMCVPHHMRVLHLGAGSDKGVAPGTAVLRR 6566
Query 6863 WLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKE 6922
WLP ++VD+D D+VSDAD ++ GDC+T++ ++K+DL+ISDMYD + K EN SKE
Sbjct 6567 WLPLDAIIVDNDSVDYVSDADYSVTGDCSTLYLSDKFDLVISDMYDGKIKSCDGENVSKE 6626
Query 6923 GFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLI 6982
GFF Y+ G I +KLALGG++A+K+TE SWN LY+L+ F +WT F T+VN SSSEAFLI
Sbjct 6627 GFFPYINGVITEKLALGGTVAIKVTEFSWNKKLYELIQKFEYWTMFCTSVNTSSSEAFLI 6686
Query 6983 GANYLG--KPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEN 7040
G +YLG IDG TMHANYIFWRN+ + +S S+ D+SKF K + T V++LK++
Sbjct 6687 GVHYLGDFASGAVIDGNTMHANYIFWRNSTIMTMSYNSVLDLSKFNCKHKATVVVNLKDS 6746
Query 7041 QINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
I+D++ LL+ G+L++R N+ + S+ LVN
Sbjct 6747 SISDVVLGLLKNGKLLVRNNDAICGFSNHLVN 6778
Score = 88.2 bits (217), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 86/282 (30%), Positives = 133/282 (47%), Gaps = 29/282 (10%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLH 1094
+VNAAN L HGGG+A A++ T G +QK S+DYIK +GP+ VG +L L K +
Sbjct 1317 VVNAANEKLSHGGGIAKAIDVYTKGMLQKCSNDYIKAHGPIKVGRGVMLEA--LGLKVFN 1374
Query 1095 VVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGA---KPLQSLQVCVQTVRTQV 1151
VVGP L+KA F + + L PL+S GIF + L + CV +
Sbjct 1375 VVGPRKGKHAPELLVKAYKSVFANSGVALTPLISVGIFSVPLEESLSAFLACVGDRHCKC 1434
Query 1152 YIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPV--DVKP-KI 1208
+ DK + ++ Y+D L V+A +E +T + + + V QKPV + +P +I
Sbjct 1435 F-CYGDKE--REAIIKYMDGL---VDAIFKEALVDTTPVQEDVQQVSQKPVLPNFEPFRI 1488
Query 1209 KA------CIDEVTTTLEETKFL--TNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP 1260
+ C E +L K + TN L F + GK +D + E ++ +K
Sbjct 1489 EGAHAFYECNPEGLMSLGADKLVLFTNSNLDFCSV-GKCLNDVTSGALLEAINVFKKSNK 1547
Query 1261 YM-VGDVITSG-----DITCVVIPSKKAGGTTEMLSRALKKV 1296
+ G+ +T IT VV+P + +RA+ KV
Sbjct 1548 TVPAGNCVTLDCANMISITMVVLPFDGDANYDKNYARAVVKV 1589
Score = 51.2 bits (121), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 82/327 (25%), Positives = 131/327 (40%), Gaps = 37/327 (11%)
Query 1543 KTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
K++ + T D ++ V+ + TYGQQ GP ++ VT KP V V+P+ +
Sbjct 1631 KSVVIKVTEDTRSVKAVKVESTATYGQQIGPCLVNDTVVTDNKPVVADVVAK--VVPNAN 1688
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQ--VGGLTSIKWADNNCYLSSVLLAL 1660
++ ++ D++ G + L+HT + FP V G IK DNNC+++ L L
Sbjct 1689 ------WDSHYGFDKA--GEF-HMLDHTG-FTFPSEVVNGRRVIKTTDNNCWVNVTCLQL 1738
Query 1661 QQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQH---AN 1717
Q +F + LQ + GD A F + + G+ D + L ++ A
Sbjct 1739 QFARFRFKSAGLQAMWESYCTGDVAMFVHWLYWLTGVDKGQPSDSENALNMLSKYIVPAG 1798
Query 1718 LESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIP-CVCGRD-ATQYLV 1775
+ +RV + C C ++ T V A + LK GV C G + + +V
Sbjct 1799 SVTIERVTHDGC-CCSKRVVTAPVVNASV---------LKLGVEDGLCPHGLNYIGKVVV 1848
Query 1776 QQESSFVMMSAPPAEYKLQQGTFLCANEYT-----GNYQCGHYTHITAKETLYRIDGAHL 1830
+ ++ V+ P FL YT GN GHYT + DG
Sbjct 1849 VKGTTIVVNVGKPV--VAPSHLFLKGVSYTTFLDNGNGVVGHYTVFDHGTGMVH-DGDAF 1905
Query 1831 TKMSEYKGPVTDVFYKETSYTTTIKPV 1857
PVT+V E + PV
Sbjct 1906 VPGDLNVSPVTNVVVSEQTAVVIKDPV 1932
Score = 40.8 bits (94), Expect = 0.79, Method: Compositional matrix adjust.
Identities = 31/101 (31%), Positives = 49/101 (49%), Gaps = 8/101 (8%)
Query 1633 WKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALIL 1692
+ F GGL ++ + NNC+++S L+ LQ L + + PA+ E + R G C
Sbjct 1073 FDFVSYGGLKVLRQSHNNCWVTSTLVQLQLLGI-VDDPAM-ELFSAGRVGPMVRKC---Y 1127
Query 1693 AYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCG 1733
+G LGDV + L + +L + K +VVC CG
Sbjct 1128 ESQKAILGSLGDVSACLESLTK--DLHTLKITCSVVCG-CG 1165
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 4286 bits (11117), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2307/5038 (46%), Positives = 3137/5038 (62%), Gaps = 229/5038 (5%)
Query 2096 LKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQ 2155
L T+A I + S + P + I+ + AQ+ F + +V +
Sbjct 1858 LSTLAVTAIVVVGGCVTSNV-----PTIVSEKISVMDKLDTGAQKFFQ-FGDFVMNNIVL 1911
Query 2156 LCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKF---SKLFTIAM-WLL 2211
T+ S S +R T+I K+ +K +AK G+ +S K+ S LF I W +
Sbjct 1912 FLTWLLSMFSLLR----TSIMKHDIKVIAKAPKRTGVILTRSFKYNIRSALFVIKQKWCV 1967
Query 2212 LLSICLGSLICVTAAFGVLLSNFGAPS---YCNGVRELYLNSSNVTTMDFCEGSFPCSIC 2268
++++ L+ V + +P C + Y S+ + +C S C +C
Sbjct 1968 IVTLFKFLLLLYAIYALVFMIVQFSPFNSLLCGDIVSGYEKSTFNKDI-YCGNSMVCKMC 2026
Query 2269 LSGLDSLDSYPALETIQVTISSYK--LDLTILGLAAEWVLAYML-FTKFFYLLGLSAIMQ 2325
L SY + T +K D ++ L +L +L F + GL +
Sbjct 2027 LF------SYQEFNDLDHTSLVWKHIRDPILISLQPFVILVILLIFGNMYLRFGLLYFVA 2080
Query 2326 VFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYY--IWKSYVHIMDGCTS 2383
F F S F+ WF+ P + F A+F I HI+ GC +
Sbjct 2081 QFISTFGS-FLGFHQKQWFL----HFVPFDVLCNE--FLATFIVCKIVLFVRHIIVGCNN 2133
Query 2384 STCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFIS 2443
+ C+ C K R RV TI+NGM +SFYV ANGG FC HN+ C+NCD+F G+TFI+
Sbjct 2134 ADCVACSKSARLKRVPLQTIINGMHKSFYVNANGGTCFCNKHNFFCVNCDSFGPGNTFIN 2193
Query 2444 DEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLY---------FDKAGQKTYERHP 2494
++AR+L K + PT + I+D V NG LY FD K +
Sbjct 2194 GDIARELGNVVKTAVQPTAPAYVIIDKVDFVNGFYRLYSGDTFWRYDFDITESKYSCKEV 2253
Query 2495 LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALV 2554
L + L+N N GS + + K+A VY+SQL+C+PI L++ L+
Sbjct 2254 LKNCNVLENFIVYNNSGS--------------NITQIKNACVYFSQLLCEPIKLVNSELL 2299
Query 2555 SDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAA 2614
S + S + + + AYVD +F ++L A ++ A + G+
Sbjct 2300 STL--SVDFNGVLHKAYVDVLCNSF---FKELTANMSMAECKATLGLT------------ 2342
Query 2615 RQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVEN-MTPRDLGACIDCNA 2673
V D + + +H D+ ++ S NNF ++Y K E+ ++ D+ C+ +
Sbjct 2343 --------VSDDDFVSAVANAHRYDVLLSDLSFNNFFISYAKPEDKLSVYDIACCMRAGS 2394
Query 2674 RHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITT 2733
+ +N V ++ ++W VKD+ +LS++ +K + K + F LT + + V T
Sbjct 2395 KVVNHNVLIKESIPIVWGVKDFNTLSQEGKKYLVKTTKAKGLTFLLTFNDNQAITQVPAT 2454
Query 2734 KISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGV 2793
I K G + + L V + + T++ GY +K I++G
Sbjct 2455 SIVAKQGAGFKRTYNFLWYVCLFVVALFIGVSFIDYTTTVTSFHGYD-----FKYIENGQ 2509
Query 2794 TRDIISTDDCFANKHAGFDAWFSQRGGSYK-NDKSCPVVAAIITREIGFIVPGLPGTVLR 2852
+ + C N F+ W + G N CP+V + R +VPG+P V
Sbjct 2510 LKVFEAPLHCVRNVFDNFNQWHEAKFGVVTTNSDKCPIVVGVSERIN--VVPGVPTNVY- 2566
Query 2853 AINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATS-ACVLAAECTIFKDAMGKPVPYCY 2911
+ + L F G +CY ++ TS C+ + CT + G V YCY
Sbjct 2567 LVGKTLVFTLQAAFGNTG-VCY------DFDGVTTSDKCIFNSACTRLEGLGGDNV-YCY 2618
Query 2912 DTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDAEYCRHGTCERSE 2970
+T+L+EGS YS L+P+ Y + ++FP G +R + T YCR G C S
Sbjct 2619 NTDLIEGSKPYSTLQPNAYYKYDAKNYVRFPEILARGFGLRTIRTLATRYCRVGECRDSH 2678
Query 2971 VGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGII 3030
G+C +W +N+ R G CG ++L+ N+ + + +S ++ +
Sbjct 2679 KGVCFGFD-KWYVNDG--RVDDGYICGDGLIDLLVNVLSIFSSSFSVVAMSGHMLFNFLF 2735
Query 3031 AILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILC--LVPAYSFLPG---VYSVF 3085
A +T + KF+RVFG+ ++ V FT++C L+ S++ + +
Sbjct 2736 AAFITFLCFLVTKFKRVFGDLSYGV----------FTVVCATLINNISYVVTQNLFFMLL 2785
Query 3086 YLYLTFYFTNDV--SFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRV- 3142
Y L F FT V +++ H+ + + ++P+W+ + F L+ N + ++
Sbjct 2786 YAILYFVFTRTVRYAWIWHIAYIVAYFLLIPWWLLTWFSFAAFLE----LLPNVFKLKIS 2841
Query 3143 --MFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALD 3199
+F G F TFE AA TF+L+ Y +L + T+ P + Y A YNKYKY+SG+
Sbjct 2842 TQLFEGDKFIGTFESAAAGTFVLDMRSYERLIN-TISP-EKLKNYAASYNKYKYYSGSAS 2899
Query 3200 TTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQ 3259
YR A HLAKA+ D++ D+LY PP S S LQSG +KMA PSG VE C+V+
Sbjct 2900 EADYRCACYAHLAKAMLDYAKDHNDMLYSPPTISYNST-LQSGLKKMAQPSGCVERCVVR 2958
Query 3260 VTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIG 3319
V G+T LNG+WL DTV CPRHVI + +L +Y+ H+F V V L V+G
Sbjct 2959 VCYGSTVLNGVWLGDTVTCPRHVIAPSTTVL-IDYDHAYSTMRLHNFSVSHNGVFLGVVG 3017
Query 3320 HSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGS 3379
+M +LR+KV SN TPK+ F ++PG +F++LACY G SGV+ +R N TIKGS
Sbjct 3018 VTMHGSVLRIKVSQSNVHTPKHVFKTLKPGDSFNILACYEGIASGVFGVNLRTNFTIKGS 3077
Query 3380 FLNGSCGSVGFNIDYD-CVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDT 3438
F+NG+CGS G+N+ D V FCY+H +EL +G H G+D G YG F D+ + Q +
Sbjct 3078 FINGACGSPGYNVRNDGTVEFCYLHQIELGSGAHVGSDFTGSVYGNFDDQPSLQVESANL 3137
Query 3439 TITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTG 3498
++ NV+A+LYAA++NG RW+L ++ FN AM Y ++ V+ L+A+TG
Sbjct 3138 MLSDNVVAFLYAALLNGCRWWLCSTRVNVDGFNEWAMANGYTSVSS--VECYSILAAKTG 3195
Query 3499 IAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHH 3558
++V + A+++ L G G+ ILG + L DEFT +VV+Q GV Q K++ G
Sbjct 3196 VSVEQLLASIQHL-HEGFGGKNILGYSSLCDEFTLAEVVKQMYGVNLQSG--KVIFGLKT 3252
Query 3559 WMLLTFLTSLLILVQSTQWSLFFFVYENA-------FLPFTLGIMAIAACAMLLVKHKHA 3611
L + ++ W+ F +Y N P ++ ++ + +KHK
Sbjct 3253 MFLFSVFFTMF-------WAELF-IYTNTIWINPVILTPIFCLLLFLSLVLTMFLKHKFL 3304
Query 3612 FLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLIL 3671
FL +FLLP++ A +N V ++++ + + S+ ++ V L ++ L
Sbjct 3305 FLQVFLLPTVIATALYNCVL--DYYIVKFLADHFNYNVSVLQMDVQGLVNVLVCLFVVFL 3362
Query 3672 MTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFL 3731
T R + + ++I + Y +Y + M+ IS + Y G + + L
Sbjct 3363 HTWRFSKERFTHWFTYVCSLIAVAYTYFYSGDFLSLLVMFLCAIS-SDWYIGAI--VFRL 3419
Query 3732 ARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYL 3791
+R IVF E +F ++ ++VY GY C Y+G+ NR+F+ T+GVYD+
Sbjct 3420 SRLIVFFSPES---VFSVFGDVKLTLVVYLICGYLVCTYWGILYWFNRFFKCTMGVYDFK 3476
Query 3792 VSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLS 3851
VS EF+YM + GL P DA L+ KLLGIGG CIK++TVQSK++D+KCT+VVLL
Sbjct 3477 VSAAEFKYMVANGLHAPHGPFDALWLSFKLLGIGGDRCIKISTVQSKLTDLKCTNVVLLG 3536
Query 3852 VLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEM 3911
L + + ++S WA CV LHN I L D +A +++LL+ LS ++ L +
Sbjct 3537 CLSSMNIAANSSEWAYCVDLHNKINLCDDPEKAQSMLLALLAFFLSKHSDFGLDGLIDSY 3596
Query 3912 LDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRD 3971
DN +TLQ++AS F S+PSY AY A++AYE A+ANG S ++K+LK+++N+AKSEFD +
Sbjct 3597 FDNSSTLQSVASSFVSMPSYIAYENARQAYEDAIANGSSSQLIKQLKRAMNIAKSEFDHE 3656
Query 3972 AAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARD 4031
++Q+K+ +MA+QA TQMYK+ARS ++++KV SAM ++LF MLR+LD ++ ++N ARD
Sbjct 3657 ISVQKKINRMAEQAATQMYKEARSVNRKSKVISAMHSLLFGMLRRLDMSSVETVLNLARD 3716
Query 4032 GCVPLNIIPLTTAAKLMVVVPDYGTY-KNTCDGNTFTYASALWEIQQVVDADSKIVQLSE 4090
G VPL++IP T+A+KL +V PD +Y K CDG+ YA +W + V D D + V + E
Sbjct 3717 GVVPLSVIPATSASKLTIVSPDLESYSKIVCDGSVH-YAGVVWTLNDVKDNDGRPVHVKE 3775
Query 4091 INMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN 4150
I +N L WPLI+ R VKLQNNE+ P L+Q A D NAL YN
Sbjct 3776 ITKENVETLTWPLILNCERV---VKLQNNEIMPGKLKQKPMKAEGDGGVLGDGNAL--YN 3830
Query 4151 NSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKG 4210
G F+ A +S+ DLK+ ++ G TI EL+ PCRF+ +TP GP+VKYLYF+K
Sbjct 3831 TEGGKTFMYAYISNKADLKFVKWEYEGGCNTI--ELDSPCRFMVETPNGPQVKYLYFVKN 3888
Query 4211 LNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITN 4270
LN L RG VLG + AT+RLQAG TE+ NS +L+ CAF+VDPA Y + + G +P++N
Sbjct 3889 LNTLRRGAVLGFIGATIRLQAGKQTELAVNSGLLTACAFSVDPATTYLEAVKHGAKPVSN 3948
Query 4271 CVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIP 4330
C+KML G GQAIT + +AN +Q+S+GGAS CLYCR H+ HP+ G+C KGK VQ+P
Sbjct 3949 CIKMLSNGAGNGQAITTSVDANTNQDSYGGASICLYCRAHVPHPSMDGYCKFKGKCVQVP 4008
Query 4331 TTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLTP 4390
C DP+ F L N VC VCG W G+GC+CD+ +QS D S +LNR G SAARL P
Sbjct 4009 IGCL-DPIRFCLENNVCNVCGCWLGHGCACDR---TTIQSVDIS-YLNRARGSSAARLEP 4063
Query 4391 CGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQ 4450
C GT D RAFDIYN+ V+ K LK NC RF+ D L D YFV+KR T S +
Sbjct 4064 C-NGTDIDKCVRAFDIYNKNVSFLGKCLKMNCVRFKNAD----LKDGYFVIKRCTKSVME 4118
Query 4451 HEETIYNLVKDCPAVAVHDFFKFRVDGDMV-PHISRQRLTKYTMADLVYALRHFDEGNCD 4509
HE+++YNL+ A+A HDFF ++ DG ++ ++SR LTKYTM DLVYA+R+FDE NCD
Sbjct 4119 HEQSMYNLLNFSGALAEHDFFTWK-DGRVIYGNVSRHNLTKYTMMDLVYAMRNFDEQNCD 4177
Query 4510 TLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAG 4569
LKE+LV CCD+ YF+ K WYD VEN DI RVYA+LG+ V +++LK V CDAM G
Sbjct 4178 VLKEVLVLTGCCDNSYFDSKGWYDPVENEDIHRVYASLGKIVARAMLKCVALCDAMVAKG 4237
Query 4570 IVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDAD 4629
+VGVLTLDNQDLNGN+YDFGDFV P GVP SYYS +MPI+ LT LA+E + +D
Sbjct 4238 VVGVLTLDNQDLNGNFYDFGDFVVSLPNMGVPCCTSYYSYMMPIMGLTNCLASECFVKSD 4297
Query 4630 LAKPLIK-WDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFST 4688
+ K +DLLKYDFTE + LF++YFK+W YHPNC +C DD C++HCANFN LF+T
Sbjct 4298 IFGSDFKTFDLLKYDFTEHKENLFNKYFKHWSFDYHPNCSDCYDDMCVIHCANFNTLFAT 4357
Query 4689 VFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPA 4748
P T+FGPL RK+F+DGVP V + GYHF++LG+V N+DVN HS RL+ ELL + DP+
Sbjct 4358 TIPGTAFGPLCRKVFIDGVPLVTTAGYHFKQLGLVWNKDVNTHSVRLTITELLQFVTDPS 4417
Query 4749 MHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKH 4808
+ AS L+D+RT CFSVAAL+ + Q VKPG+FN++FY+F +GFF EGS + LKH
Sbjct 4418 LIIASSPALVDQRTICFSVAALSTGLTNQVVKPGHFNEEFYNFLRLRGFFDEGSELTLKH 4477
Query 4809 FFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLD 4868
FFFAQ+G+AA+ D+D+YRYN PT+ DI Q ++V +YFD Y+GGCI A +V+V NL+
Sbjct 4478 FFFAQNGDAAVKDFDFYRYNKPTILDICQARVTYKIVSRYFDIYEGGCIKACEVVVTNLN 4537
Query 4869 KSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAG 4928
KSAG+P NK+GKA LYY+S+SYE+QDALFA TKRNV+PT+TQ+NLKYAIS K RARTV G
Sbjct 4538 KSAGWPLNKFGKASLYYESISYEEQDALFALTKRNVLPTMTQLNLKYAISGKERARTVGG 4597
Query 4929 VSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDY 4988
VS+ STMT RQ+HQK LKSI TR ATVVIGT+KFYGGW+NML+T+ VE P LMGWDY
Sbjct 4598 VSLLSTMTTRQYHQKHLKSIVNTRNATVVIGTTKFYGGWNNMLRTLIDGVENPMLMGWDY 4657
Query 4989 PKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGG 5048
PKCDRA+PNM+R+++++VL KH CC + RFYRL NE AQVL+E+V G Y KPGG
Sbjct 4658 PKCDRALPNMIRMISAMVLGSKHVNCCTATDRFYRLGNELAQVLTEVVYSNGGFYFKPGG 4717
Query 5049 TSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDH 5108
T+SGDA+TAYANS+FNI QAV++N+N LLS + + VR+LQ RLY+ YR V+
Sbjct 4718 TTSGDASTAYANSIFNIFQAVSSNINRLLSVPSDSCNNVNVRDLQRRLYDNCYRLTSVEE 4777
Query 5109 EFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKC 5168
F+D++Y YLRKHFSMMILSDD VVCYN +YA G +A I FKA LYYQNNVFMS +KC
Sbjct 4778 SFIDDYYGYLRKHFSMMILSDDGVVCYNKDYAELGYIADISAFKATLYYQNNVFMSTSKC 4837
Query 5169 WTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERF 5228
W E DLTKGPHEFCSQHTM + D YLPYPDPSRIL AG FVDD+VKTD +++ER+
Sbjct 4838 WVEEDLTKGPHEFCSQHTMQIVDKDGTYYLPYPDPSRILSAGVFVDDVVKTDAVVLLERY 4897
Query 5229 VSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPE 5288
VSLAIDAYPL+KHPN EY VF++ L +++ L+ L +L+ +SV L ++ ++W +
Sbjct 4898 VSLAIDAYPLSKHPNSEYRKVFYVLLDWVKHLNKNLNEGVLESFSVTLLDNQEDKFWCED 4957
Query 5289 FYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNP 5348
FY +MY T+LQA G CV+C SQT LRCG C+R+P LC KC YDHV T HK +L++ P
Sbjct 4958 FYASMYENSTILQAAGLCVVCGSQTVLRCGDCLRKPMLCTKCAYDHVFGTDHKFILAITP 5017
Query 5349 YVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFN 5408
YVCNA GC V+DV +LYLGG++YYC +HKP +SFPLC+ G +FGLYKN+ GS +V FN
Sbjct 5018 YVCNASGCGVSDVKKLYLGGLNYYCTNHKPQLSFPLCSAGNIFGLYKNSATGSLDVEVFN 5077
Query 5409 AIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSW 5468
+AT DWT+ DY LAN + L+LFAAET+KA EE+ K SY AT++EV+ +EL LSW
Sbjct 5078 RLATSDWTDVRDYKLANDVKDTLRLFAAETIKAKEESVKSSYAFATLKEVVGPKELLLSW 5137
Query 5469 EVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYG-DAVVYRGTTTYKLNVGDYFV 5527
E GK +PPLNRN VFT ++++K+SK QIGE+ FEK +YG D V Y+ T T KL G FV
Sbjct 5138 ESGKVKPPLNRNSVFTCFQISKDSKFQIGEFIFEKVEYGSDTVTYKSTVTTKLVPGMIFV 5197
Query 5528 LTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGT 5587
LTSH V PL APT+ QE Y I L+P N+SD +++ V YQ +G QK +T+QGPPG+
Sbjct 5198 LTSHNVQPLRAPTIANQEKYSSIYKLHPAFNVSDAYANLVPYYQLIGKQKITTIQGPPGS 5257
Query 5588 GKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKF 5647
GKSH +IGL LYYP ARIV+ AC+HAAVD+LC KA+ IDKC+RIIPARARVEC+ F
Sbjct 5258 GKSHCSIGLGLYYPGARIVFVACAHAAVDSLCAKAMTVYSIDKCTRIIPARARVECYSGF 5317
Query 5648 KVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLP 5707
K N+T QY+F TVNALPE ADIVV DE+SM TNYDLSV+N RL KH VY+GDP QLP
Sbjct 5318 KPNNTSAQYIFSTVNALPECNADIVVVDEVSMCTNYDLSVINQRLSYKHIVYVGDPQQLP 5377
Query 5708 APRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD 5767
APR ++TKG +EP +N V + M IGPD+FL C RCPAEIV+TVS LVY+NK K
Sbjct 5378 APRVMITKGVMEPVDYNVVTQRMCAIGPDVFLHKCYRCPAEIVNTVSELVYENKFVPVKP 5437
Query 5768 KSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL 5827
S QCFK+F+KG + D S+INR Q+ +V+ FL +NP+W KAVFISPYNSQN VAS+ L
Sbjct 5438 ASKQCFKVFFKGNVQVDNGSSINRKQLEIVKLFLVKNPSWSKAVFISPYNSQNYVASRFL 5497
Query 5828 GLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQ 5887
GL QTVDSSQGSEYDYVI+ QT++TAH+CNVNRFNVAITRAK GI C+M D+ L+D L+
Sbjct 5498 GLQIQTVDSSQGSEYDYVIYAQTSDTAHACNVNRFNVAITRAKKGIFCVMCDKTLFDSLK 5557
Query 5888 FTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEG-LCVDIPG 5946
F EI A L + V GLFK+C++ L PT A T LS+ +FKT G L V I G
Sbjct 5558 F--FEIKH---ADLHSSQVCGLFKNCTRTPLNLPPTHAHTFLSLSDQFKTTGDLAVQI-G 5611
Query 5947 IPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTN 6006
TY +IS MGF+ + + G ++F TR+ AIR+VR W+G DVE H D +GTN
Sbjct 5612 SNNVCTYEHVISFMGFRFDISIPGSHSLFCTRDFAIRNVRGWLGMDVESAHVCGDNIGTN 5671
Query 6007 LPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRI 6066
+PLQ+GFS GVN V G V T V AK PPG+QF+HLIPL+ KG PW +VR
Sbjct 5672 VPLQVGFSNGVNFVVQTEGCVSTNFGDVIKPVCAKSPPGEQFRHLIPLLRKGQPWLIVRR 5731
Query 6067 KIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTY 6126
+IVQM+SD L LSD +VFVLWA ELT+M+YFVKIGP + C C ATC+++ S+ Y
Sbjct 5732 RIVQMISDYLSNLSDILVFVLWAGSLELTTMRYFVKIGPIKY-CYCGNSATCYNSVSNEY 5790
Query 6127 ACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHE 6186
C+ H++G DYVYNP+ D+QQWG+ G+L NH C +H N H AS DA+MTRCLAVH+
Sbjct 5791 CCFKHALGCDYVYNPYAFDIQQWGYVGSLSQNHHTFCNIHRNEHDASGDAVMTRCLAVHD 5850
Query 6187 CFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQA 6246
CFVK VDW+V YP I +E +N R VQ VV++AL K V+HDIGNPK ++C
Sbjct 5851 CFVKNVDWTVTYPFIANEKFINGCGRNVQGHVVRAALKLYKPSVIHDIGNPKGVRC-AVT 5909
Query 6247 EVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTR 6306
+ +W YD QP + ++ L Y YATH DG+CLFWNCNVD YP +IVCRFDTR
Sbjct 5910 DAKWYCYDKQPVNS---NVKLLDYDYATHGQ--LDGLCLFWNCNVDMYPEFSIVCRFDTR 5964
Query 6307 VLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDID 6366
S NL G +GGSLYVNKHAFHTPA+DK AF LK +PFFY+ DS C+ +QV +
Sbjct 5965 TRSVFNLEGVNGGSLYVNKHAFHTPAYDKRAFVKLKPMPFFYFDDSDCDVVQEQV----N 6020
Query 6367 YVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTF- 6425
YVPL++++C+TRCN+GGAVC HAN Y++Y++AYN AGF++W+ FD YNLW F
Sbjct 6021 YVPLRASSCVTRCNIGGAVCSKHANLYQKYVEAYNTFTQAGFNIWVPHSFDVYNLWQIFI 6080
Query 6426 -TRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAF 6484
T LQSLEN+A+NVV KG F G GE PV+++N+ V+ + +D +F NKTTLP NVAF
Sbjct 6081 ETNLQSLENIAFNVVKKGCFTGVDGELPVAVVNDKVFVRYGDVDNLVFTNKTTLPTNVAF 6140
Query 6485 ELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESA 6544
EL+AKR + P + IL NLGV V+WDY+ E P T VC TD E
Sbjct 6141 ELFAKRKMGLTPPLSILKNLGVVATYKFVLWDYEAERPFTSYTKSVCKYTDF----NEDV 6196
Query 6545 CSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSK-------GPAQASVNGVTLI 6597
C V FD ++G + F N VL + +K LTP K G +S+ G +
Sbjct 6197 C----VCFDNSIQGSYERFTLTTNAVLFSTVVIKNLTPIKLNFGMLNGMPVSSIKGDKGV 6252
Query 6598 GESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLE 6657
E + + Y +K +G Q + ++TQ R+L DF PRS ME DFL + M FI +Y LE
Sbjct 6253 -EKLVNWYIYVRK-NGQFQDHYDGFYTQGRNLSDFTPRSDMEYDFLNMDMGVFINKYGLE 6310
Query 6658 GYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPM-DSTVKNYFITDAQTGS 6716
+ FEH+VYGD S LGGLHL+I + S+ LK +DF+ D+T++ +T S
Sbjct 6311 DFNFEHVVYGDVSKTTLGGLHLLISQFRLSKMGVLKADDFVTASDTTLRCCTVTYLNELS 6370
Query 6717 SKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQA 6776
SK VC+ +DLLLDDFV I+KS DL VISKV +V ID +MLWCKD H+ TFYP+LQ+
Sbjct 6371 SKVVCTYMDLLLDDFVTILKSLDLGVISKVHEVIIDNKPYRWMLWCKDNHLSTFYPQLQS 6430
Query 6777 SQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAV 6836
++ W+ G AMP +YK+QRM LE C+L NYG +P GIM+NV KYTQLCQYLN+ T+ V
Sbjct 6431 AE-WKCGYAMPQIYKLQRMCLEPCNLYNYGAGIKLPSGIMLNVVKYTQLCQYLNSTTMCV 6489
Query 6837 PYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTA 6896
P+NMRV+H+GAGSDKGVAPGT VL++WLP +++D+D+ND+VSDAD ++ GDCATV+
Sbjct 6490 PHNMRVLHYGAGSDKGVAPGTTVLKRWLPPDAIIIDNDINDYVSDADFSITGDCATVYLE 6549
Query 6897 NKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLY 6956
+K+DL+ISDMYD R K EN SK+GFFTYL G I++KLA+GGS+A+KITE+SWN LY
Sbjct 6550 DKFDLLISDMYDGRIKFCDGENVSKDGFFTYLNGVIREKLAIGGSVAIKITEYSWNKYLY 6609
Query 6957 KLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQ--IDGYTMHANYIFWRNTNPIQL 7014
+L+ F++WT F T+VN SSSEAFLIG NYLG + I G T+HANYIFWRN+ + L
Sbjct 6610 ELIQRFAFWTLFCTSVNTSSSEAFLIGINYLGDFIQGPFIAGNTVHANYIFWRNSTIMSL 6669
Query 7015 SSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
S S+ D+SKF K + T V++LK++ +NDM+ SL++ GRL++R N R S+ LV+
Sbjct 6670 SYNSVLDLSKFECKHKATVVVTLKDSDVNDMVLSLIKSGRLLLRNNGRFGGFSNHLVS 6727
Score = 84.0 bits (206), Expect = 7e-14, Method: Compositional matrix adjust.
Identities = 62/179 (35%), Positives = 86/179 (48%), Gaps = 10/179 (6%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
NV DI + +VNAAN +L HGGGVA A++ T G +Q S DYI NGP
Sbjct 1265 NVKFYLGDISHLVNCVSFDFVVNAANENLLHGGGVARAIDILTEGQLQSLSKDYISSNGP 1324
Query 1075 LTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGA 1134
L VG +L +VVGP E L++A I L PLLS GIFG
Sbjct 1325 LKVGAGVMLECEKF--NVFNVVGPRTGKHEHSLLVEAYNSILFENGIPLMPLLSCGIFGV 1382
Query 1135 K---PLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLD--NLKPRVEAPKQEEPPNTE 1188
+ L++L C QV++ +++ EQ V+ +LD +L P ++ +P E
Sbjct 1383 RIENSLKALFSCDINKPLQVFVYSSNE---EQAVLKFLDGLDLTPVIDDVDVVKPFRVE 1438
Score = 52.8 bits (125), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 72/288 (25%), Positives = 119/288 (41%), Gaps = 28/288 (10%)
Query 1550 TVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLP-SDDTLRSEA 1608
T D N+ +V+ S + G+Q G DG D + EG VLP + DT+ S A
Sbjct 1587 TEDGINVKDVVVESSKSLGKQLGVVS-DGVD--------SFEG----VLPINTDTVLSVA 1633
Query 1609 FEYYHTLDESFLGRYMSALNHTKKWKFPQ--VGGLTSIKWADNNCYLSSVLLALQQLEVK 1666
E F + A K + +P VGG + DNNC++++ + LQ L+
Sbjct 1634 PEVDWVAFYGFEKAALFASLDVKPYGYPNDFVGGFRVLGTTDNNCWVNATCIILQYLKPT 1693
Query 1667 FNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLN 1726
F + L + + GD F + I + + G+ GD E ++ L ++ L S V
Sbjct 1694 FKSKGLNVLWNKFVTGDVGPFVSFIYFITMSSKGQKGDAEEALSKLSEY--LISDSIVTL 1751
Query 1727 VVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSA 1786
C +T+ V++ + ++ LK G + R + V+ + V+++
Sbjct 1752 EQYSTCDICKSTVVEVKSAIVCASV----LKDGCDVGFCPHRHKLRSRVKFVNGRVVITN 1807
Query 1787 PPAEYKLQQGTFLCANEYT---GNYQCGHY-THITAKETLYRIDGAHL 1830
Q L YT G++ GHY + A +Y DGA L
Sbjct 1808 VGEPIISQPSKLLNGIAYTTFSGSFDNGHYVVYDAANNAVY--DGARL 1853
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 4258 bits (11043), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2270/4982 (46%), Positives = 3112/4982 (62%), Gaps = 256/4982 (5%)
Query 2173 TTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAM-----WLLLLSICLGSLICVTAAF 2227
T + VK +AK G+ +S K++ + A+ WLL L LI +
Sbjct 1949 TAVTTGDVKIMAKAPQRTGVVLKRSLKYNLKASAAVLKSKWWLLAKFTKLLLLIYTLYSV 2008
Query 2228 GVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVT 2287
+L FG ++C+ Y SN D+C+GS C +CL G L + L+ +
Sbjct 2009 VLLCVRFGPFNFCSETVNGYA-KSNFVKDDYCDGSLGCKMCLFGYQELSQFSHLDVVWKH 2067
Query 2288 ISS--------YKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2339
I+ + + + +L ++ ++L+ ++ + + + VF GY ++
Sbjct 2068 ITDPLFSNMQPFIVMVLLLIFGDNYLRCFLLY----FVAQMISTVGVFLGYKETN----- 2118
Query 2340 WLMWFII--SIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATR 2397
W + FI I V+ +V I F H++ GC + C+ C K R R
Sbjct 2119 WFLHFIPFDVICDELLVTVIVIKVISFVR---------HVLFGCENPDCIACSKSARLKR 2169
Query 2398 VECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRP 2457
TIVNG++RSFYV ANGG FCK H + C++CD++ GSTFI+ EV+R+L K
Sbjct 2170 FPVNTIVNGVQRSFYVNANGGSKFCKKHRFFCVDCDSYGYGSTFITPEVSRELGNITKTN 2229
Query 2458 INPTDQSSYIVDSVAVKNGALHLY---------FDKAGQKTYERHPLSHFVNLDNLRANN 2508
+ PT + ++D V +NG LY FD K + + LD+ N
Sbjct 2230 VQPTGPAYVMIDKVEFENGFYRLYSCETFWRYNFDITESKYSCKEVFKNCNVLDDFIVFN 2289
Query 2509 TKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMF 2568
G+ + + K+ASVY+SQL+C+PI L+D L+S + S + + +
Sbjct 2290 NNGT--------------NVTQVKNASVYFSQLLCRPIKLVDSELLSTL--SVDFNGVLH 2333
Query 2569 DAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDV 2628
AY+D +F + L A ++ A + A G+++ F SA
Sbjct 2334 KAYIDVLRNSFG---KDLNANMSLAECKRALGLSISD--HEFTSAISN------------ 2376
Query 2629 IECLKLSHHSDLEVTGDSCNNFMLTYNK-VENMTPRDLGACIDCNARHINAQVAKSHNVS 2687
+H D+ ++ S NNF+ +Y K E ++ DL C+ A+ +NA V
Sbjct 2377 ------AHRCDVLLSDLSFNNFVSSYAKPEEKLSAYDLACCMRAGAKVVNANVLTKDQTP 2430
Query 2688 LIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLK--GGKIVST 2745
++W+ KD+ SLS + RK I +K + F LT + V + T I K G +
Sbjct 2431 IVWHAKDFNSLSAEGRKYIVKTSKAKGLTFLLTINENQAVTQIPATSIVAKQGAGDAGHS 2490
Query 2746 CFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFA 2805
L L L+C++ +C+ MP I + E +K I++G ++ + C
Sbjct 2491 LTWLWLLCGLVCLIQFYLCFF-MPYFMYDIVSSF--EGYDFKYIENGQLKNFEAPLKCVR 2547
Query 2806 NKHAGFDAW-FSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPR 2864
N F+ W +++ G + N +SCP+V + EI V G+P V + G L F +
Sbjct 2548 NVFENFEDWHYAKFGFTPLNKQSCPIVVGV--SEIVNTVAGIPSNVY--LVGKTLIFTLQ 2603
Query 2865 VFSAVGNICY------TPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEG 2918
+CY TP K C+ + CT + G V YCY+T L+EG
Sbjct 2604 AAFGNAGVCYDIFGVTTPEK-----------CIFTSACTRLEGLGGNNV-YCYNTALMEG 2651
Query 2919 SISYSELRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDAEYCRHGTCERSEVGICLST 2977
S+ YS ++ + Y +G+ I+ P +G R V T +YCR G C S G+C
Sbjct 2652 SLPYSSIQANAYYKYDNGNFIKLPEVIAQGFGFRTVRTIATKYCRVGECVESNAGVCFGF 2711
Query 2978 SGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCA 3037
+W +N+ R +G CG NL+ NI + +S ++ +
Sbjct 2712 D-KWFVNDG--RVANGYVCGTGLWNLVFNILSMFSSSFSVAAMSGQILLNCALGAFAIFC 2768
Query 3038 AYYFMKFRRVFGEYN----------------HVVAANALLFLMSFTILCLVPAYSFLPGV 3081
+ KFRR+FG+ + ++V N L+ ++++ IL Y F
Sbjct 2769 CFLVTKFRRMFGDLSVGVCTVVVAVLLNNVSYIVTQN-LVTMIAYAIL-----YFFATRS 2822
Query 3082 YSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKR 3141
+++ Y +SF P+W+ A Y L + L+ +
Sbjct 2823 LRYAWIWCAAYLIAYISF-------------APWWLCAWYF----LAMLTGLLPSLLKLK 2865
Query 3142 V---MFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGA 3197
V +F G F TFE AA TF+++ Y KL + ++ P + Y A YN+YKY+SG
Sbjct 2866 VSTNLFEGDKFVGTFESAAAGTFVIDMRSYEKL-ANSISP-EKLKSYAASYNRYKYYSGN 2923
Query 3198 LDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3257
+ YR A +LAKA+ DFS D+LY PP S S LQ+G RKMA PSG VE C+
Sbjct 2924 ANEADYRCACYAYLAKAMLDFSRDHNDILYTPPTVSYGST-LQAGLRKMAQPSGFVEKCV 2982
Query 3258 VQVTCGTTTLNGLWLDDTVYCPRHVICT-AEDMLNPNYEDLLIRKSNHSFLVQAGNVQLR 3316
V+V G T LNGLWL D VYCPRHVI + ++ ++E ++R H+F + +G L
Sbjct 2983 VRVCYGNTVLNGLWLGDIVYCPRHVIASNTTSAIDYDHEYSIMRL--HNFSIISGTAFLG 3040
Query 3317 VIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTI 3376
V+G +M L++KV +N TP++ F ++ G+ F++LACY+G GV+ MR N TI
Sbjct 3041 VVGATMHGVTLKIKVSQTNMHTPRHSFRTLKSGEGFNILACYDGCAQGVFGVNMRTNWTI 3100
Query 3377 KGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGT 3436
+GSF+NG+CGS G+N+ V F YMH +EL +G H G+ +G YG F D+ Q
Sbjct 3101 RGSFINGACGSPGYNLKNGEVEFVYMHQIELGSGSHVGSSFDGVMYGGFEDQPNLQVESA 3160
Query 3437 DTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQ 3496
+ +T+NV+A+LYAA++NG W+L + +N A + + + D L+A+
Sbjct 3161 NQMLTVNVVAFLYAAILNGCTWWLKGEKLFVEHYNEWAQANGFTAMNGE--DAFSILAAK 3218
Query 3497 TGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ-GKFKKIVKG 3555
TG+ V + A+ ++L NG G+ ILG + L DEF+ +VV+Q GV Q GK + K
Sbjct 3219 TGVCVERLLHAI-QVLNNGFGGKQILGYSSLNDEFSINEVVKQMFGVNLQSGKTTSMFKS 3277
Query 3556 THHWM-LLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLC 3614
+ + L + +T W V PF + ++A++ C +VKHK FL
Sbjct 3278 ISLFAGFFVMFWAELFVYTTTIW-----VNPGFLTPFMILLVALSLCLTFVVKHKVLFLQ 3332
Query 3615 LFLLPSLATVAYFNMVYMPASW---VMRIMTWLELADTSLSGYRLKDCVMYASALVLLIL 3671
+FLLPS+ A N +W V +++ + S+ ++ V L + +L
Sbjct 3333 VFLLPSIIVAAIQN-----CAWDYHVTKVLAEKFDYNVSVMQMDIQGFVNIFICLFVALL 3387
Query 3672 MTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFL 3731
T R + L ++I ++Y Y +S+ +++ SN + I +
Sbjct 3388 HTWRFAKERCTHWCTYLFSLIAVLYTALYSY---DYVSLLVMLLCAISNEWYIGAIIFRI 3444
Query 3732 AR-AIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDY 3790
R + F+ VEY + ++ ++L Y LG+ C Y+GL +NR+ + TLGVYD+
Sbjct 3445 CRFGVAFLPVEYVSYF----DGVKTVLLFYMLLGFVSCMYYGLLYWINRFCKCTLGVYDF 3500
Query 3791 LVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLL 3850
VS EF+YM + GL P DA L+ KL+GIGG IKV+TVQSK++D+KCT+VVL+
Sbjct 3501 CVSPAEFKYMVANGLNAPNGPFDALFLSFKLMGIGGPRTIKVSTVQSKLTDLKCTNVVLM 3560
Query 3851 SVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEE 3910
+L + + S+SK WA CV++HN I L D A E +++LL+ LS + L +
Sbjct 3561 GILSNMNIASNSKEWAYCVEMHNKINLCDDPETAQELLLALLAFFLSKHSDFGLGDLVDS 3620
Query 3911 MLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR 3970
+N + LQ++AS F +PS+ AY TA++ YE AVANG S ++K+LKK++NVAK+EFDR
Sbjct 3621 YFENDSILQSVASSFVGMPSFVAYETARQEYENAVANGSSPQIIKQLKKAMNVAKAEFDR 3680
Query 3971 DAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNAR 4030
++++Q+K+ +MA+QA MYK+AR+ ++++KV SAM ++LF MLR+LD +++ I+N AR
Sbjct 3681 ESSVQKKINRMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNMAR 3740
Query 4031 DGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSE 4090
+G VPL++IP T+AA+L+VVVPD+ ++ YA +W +Q+V D D K V L +
Sbjct 3741 NGVVPLSVIPATSAARLVVVVPDHDSFVKMMVDGFVHYAGVVWTLQEVKDNDGKNVHLKD 3800
Query 4091 INMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN 4150
+ +N L WPLI+T R VKLQNNE+ P ++ + ++ NAL YN
Sbjct 3801 VTKENQEILVWPLILTCERV---VKLQNNEIMPGKMKVKATKGEGDGGITSEGNAL--YN 3855
Query 4151 NSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKG 4210
N G F+ A ++ +K+ ++ G T+ ELEPPCRFV DTP GP++KYLYF+K
Sbjct 3856 NEGGRAFMYAYVTTKPGMKYVKWEHDSGVVTV--ELEPPCRFVIDTPTGPQIKYLYFVKN 3913
Query 4211 LNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITN 4270
LNNL RG VLG + ATVRLQAG TE +NS +L+ C+FAVDPA AY D + G +P+ N
Sbjct 3914 LNNLRRGAVLGYIGATVRLQAGKQTEFVSNSHLLTHCSFAVDPAAAYLDAVKQGAKPVGN 3973
Query 4271 CVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIP 4330
CVKML +G+GQAIT T ++N Q+++GGAS C+YCR H+ HP GFC KGK+VQ+P
Sbjct 3974 CVKMLTNGSGSGQAITCTIDSNTTQDTYGGASVCIYCRAHVAHPTMDGFCQYKGKWVQVP 4033
Query 4331 TTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLTP 4390
NDP+ F L NTVC VCG W +GC+CD+ +QS D S +LNRV G SAARL P
Sbjct 4034 IG-TNDPIRFCLENTVCKVCGCWLNHGCTCDR---TAIQSFDNS-YLNRVRGSSAARLEP 4088
Query 4391 CGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQ 4450
C GT D RAFD+YN+ + K LK+NC RF+ D++ D++++VKR S
Sbjct 4089 C-NGTDIDYCVRAFDVYNKDASFIGKNLKSNCVRFKNVDKD----DAFYIVKRCIKSVMD 4143
Query 4451 HEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDT 4510
HE+++YNL+K C AVA HDFF + + ++SRQ LTKYTM DL +ALR+FDE +C+
Sbjct 4144 HEQSMYNLLKGCNAVAKHDFFTWHEGRTIYGNVSRQDLTKYTMMDLCFALRNFDEKDCEV 4203
Query 4511 LKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGI 4570
KEILV CC DYF K+W+D +EN DI RVYA LG+ V ++LK V FCD M G+
Sbjct 4204 FKEILVLTGCCSTDYFEMKNWFDPIENEDIHRVYAALGKVVANAMLKCVAFCDEMVLKGV 4263
Query 4571 VGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADL 4630
VGVLTLDNQDLNGN+YDFGDFV PG G+P SYYS +MP++ +T LA+E M +D+
Sbjct 4264 VGVLTLDNQDLNGNFYDFGDFVLCPPGMGIPYCTSYYSYMMPVMGMTNCLASECFMKSDI 4323
Query 4631 -AKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTV 4689
+ +DLLKYDFTE + LF++YFKYW Q YHP+C++C D+ CILHC+NFN LF+T
Sbjct 4324 FGQDFKTFDLLKYDFTEHKEVLFNKYFKYWGQDYHPDCVDCHDEMCILHCSNFNTLFATT 4383
Query 4690 FPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAM 4749
P T+FGPL RK+F+DGVP V + GYHF++LG+V N+DVN HS+RL+ ELL + DP +
Sbjct 4384 IPNTAFGPLCRKVFIDGVPVVATAGYHFKQLGLVWNKDVNTHSTRLTITELLQFVTDPTL 4443
Query 4750 HAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHF 4809
AS L+DKRT CFSVAAL+ + QTVKPG+FNK+FYDF S+GFF EGS + LKHF
Sbjct 4444 IVASSPALVDKRTVCFSVAALSTGLTSQTVKPGHFNKEFYDFLRSQGFFDEGSELTLKHF 4503
Query 4810 FFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDK 4869
FF Q G+AAI D+DYYRYN PTM DI Q +V +YFDCY+GGCI + +V+V NL+K
Sbjct 4504 FFTQKGDAAIKDFDYYRYNRPTMLDIGQARVAYQVAARYFDCYEGGCITSREVVVTNLNK 4563
Query 4870 SAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGV 4929
SAG+P NK+GKA LYY+S+SYE+QDA+F+ TKRN++PT+TQ+NLKYAIS K RARTV GV
Sbjct 4564 SAGWPLNKFGKAGLYYESISYEEQDAIFSLTKRNILPTMTQLNLKYAISGKERARTVGGV 4623
Query 4930 SICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYP 4989
S+ +TMT RQFHQK LKSI ATR ATVVIGT+KFYGGW NMLK + +DV+ P LMGWDYP
Sbjct 4624 SLLATMTTRQFHQKCLKSIVATRNATVVIGTTKFYGGWDNMLKNLMADVDDPKLMGWDYP 4683
Query 4990 KCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGT 5049
KCDRAMP+M+R++++++L KH TCC S +FYRL+NE AQVL+E+V G Y KPGGT
Sbjct 4684 KCDRAMPSMIRMLSAMILGSKHVTCCTASDKFYRLSNELAQVLTEVVYSNGGFYFKPGGT 4743
Query 5050 SSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHE 5109
+SGDATTAYANSVFNI QAV++N+N +LS + + + V+ LQ +LY+ YRN +VD
Sbjct 4744 TSGDATTAYANSVFNIFQAVSSNINCVLSVNSSNCNNFNVKKLQRQLYDNCYRNSNVDES 4803
Query 5110 FVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCW 5169
FVD+FY YL+KHFSMMILSDD+VVCYN YA G +A I FKA LYYQN VFMS AKCW
Sbjct 4804 FVDDFYGYLQKHFSMMILSDDSVVCYNKTYAGLGYIADISAFKATLYYQNGVFMSTAKCW 4863
Query 5170 TETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFV 5229
TE DL+ GPHEFCSQHTM + + YLPYPDPSRI+ AG FVDDI KTD +++ER+V
Sbjct 4864 TEEDLSIGPHEFCSQHTMQIVDENGKYYLPYPDPSRIISAGVFVDDITKTDAVILLERYV 4923
Query 5230 SLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEF 5289
SLAIDAYPL+KHP EY VF+ L +++ L+ L +L+ +SV L +++ S++W+ F
Sbjct 4924 SLAIDAYPLSKHPKPEYRKVFYALLDWVKHLNKTLNEGVLESFSVTLLDEHESKFWDESF 4983
Query 5290 YEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPY 5349
Y +MY TVLQA G CV+C SQT LRCG C+RRP LC KC YDHV T HK +L++ PY
Sbjct 4984 YASMYEKSTVLQAAGLCVVCGSQTVLRCGDCLRRPMLCTKCAYDHVFGTDHKFILAITPY 5043
Query 5350 VCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNA 5409
VCN GC+V DVT+LYLGG++YYC HKP +SFPLC+ G VFGLYK++ +GS ++ FN
Sbjct 5044 VCNTSGCNVNDVTKLYLGGLNYYCVDHKPHLSFPLCSAGNVFGLYKSSALGSMDIDVFNK 5103
Query 5410 IATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWE 5469
++T DW++ DY LAN E L+LFAAET+KA EE+ K SY AT++E++ +EL L WE
Sbjct 5104 LSTSDWSDIRDYKLANDAKESLRLFAAETVKAKEESVKSSYAYATLKEIVGPKELLLLWE 5163
Query 5470 VGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYG-DAVVYRGTTTYKLNVGDYFVL 5528
GK +PPLNRN VFT +++TK+SK Q+GE+ FEK DYG D V Y+ T T KL G F+L
Sbjct 5164 SGKAKPPLNRNSVFTCFQITKDSKFQVGEFVFEKVDYGSDTVTYKSTATTKLVPGMLFIL 5223
Query 5529 TSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTG 5588
TSH V PL APT+ QE Y I L+P+ N+SD +++ V YQ +G Q+ +T+QGPPG+G
Sbjct 5224 TSHNVAPLRAPTMANQEKYSTIYKLHPSFNVSDAYANLVPYYQLIGKQRITTIQGPPGSG 5283
Query 5589 KSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFK 5648
KSH +IG+ +YYP ARIV+TACSHAAVD+LC KA+ +DKC+RIIPARARVEC+ FK
Sbjct 5284 KSHCSIGIGVYYPGARIVFTACSHAAVDSLCAKAVTAYSVDKCTRIIPARARVECYSGFK 5343
Query 5649 VNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPA 5708
N+ QYVF TVNALPE ADIVV DE+SM TNYDLSV+N R+ KH VY+GDP QLPA
Sbjct 5344 PNNNSAQYVFSTVNALPEVNADIVVVDEVSMCTNYDLSVINQRISYKHIVYVGDPQQLPA 5403
Query 5709 PRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDK 5768
PR L++KG +EP +N V + M IGPD+FL C RCPAEIV+TVS LVY+NK K+
Sbjct 5404 PRVLISKGVMEPIDYNVVTQRMCAIGPDVFLHKCYRCPAEIVNTVSELVYENKFVPVKEA 5463
Query 5769 SAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILG 5828
S QCFK+F +G + D S+INR Q+ VV+ F+ +N W KAVFISPYNSQN VA+++LG
Sbjct 5464 SKQCFKIFERGSVQVDNGSSINRRQLDVVKRFIHKNSTWSKAVFISPYNSQNYVAARLLG 5523
Query 5829 LPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQF 5888
L TQTVDS+QGSEYDYVIF QT++TAH+CN NRFNVAITRAK GI CIMSDR L+D L+F
Sbjct 5524 LQTQTVDSAQGSEYDYVIFAQTSDTAHACNANRFNVAITRAKKGIFCIMSDRTLFDALKF 5583
Query 5889 TSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEG-LCVDIPGI 5947
+ + LQ+E+ GLFKDC++ L P+ A T+LS+ +FKT G L V I G
Sbjct 5584 FEITM-----TDLQSESSCGLFKDCARNPIDLPPSHATTYLSLSDRFKTSGDLAVQI-GN 5637
Query 5948 PKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNL 6007
TY +IS MGF+ + + G ++F TR+ A+RHVR W+G DVEG H T D VGTN+
Sbjct 5638 NNVCTYEHVISYMGFRFDVSMPGSHSLFCTRDFAMRHVRGWLGMDVEGAHVTGDNVGTNV 5697
Query 6008 PLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIK 6067
PLQ+GFS GV+ VA P G V T + V A+ PPG+QF H++PL+ KG PW+V+R +
Sbjct 5698 PLQVGFSNGVDFVAQPEGCVLTNTGSVVKPVRARAPPGEQFTHIVPLLRKGQPWSVLRKR 5757
Query 6068 IVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYA 6127
IVQM++D L G SD +VFVLWA G ELT+M+YFVKIG + C C ATC+++ S+ Y
Sbjct 5758 IVQMIADFLAGSSDVLVFVLWAGGLELTTMRYFVKIGAVKH-CQCGTVATCYNSVSNDYC 5816
Query 6128 CWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHEC 6187
C+ H++G DYVYNP++ID+QQWG+ G+L +NH C VH N HVAS DAIMTRCLAV++C
Sbjct 5817 CFKHALGCDYVYNPYVIDIQQWGYVGSLSTNHHAICNVHRNEHVASGDAIMTRCLAVYDC 5876
Query 6188 FVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAE 6247
FVK VDWS+ YP+I +E +N R VQ ++++A+ +HDIGNPK I+C +
Sbjct 5877 FVKNVDWSITYPMIANENAINKGGRTVQSHIMRAAIKLYNPKAIHDIGNPKGIRCAV-TD 5935
Query 6248 VEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRV 6307
+W YD P + +E Y Y TH DG+CLFWNCNVD YP +IVCRFDTR
Sbjct 5936 AKWYCYDKNPINSNVKTLE---YDYMTHGQ--MDGLCLFWNCNVDMYPEFSIVCRFDTRT 5990
Query 6308 LSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSD-ID 6366
S LNL G +GGSLYVN HAFHTPA+DK A LK PFFYY D CE VV D ++
Sbjct 5991 RSTLNLEGVNGGSLYVNNHAFHTPAYDKRAMAKLKPAPFFYYDDGSCE-----VVHDQVN 6045
Query 6367 YVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFT 6426
YVPL++ CIT+CN+GGAVC HAN YR Y+++YN+ AGF++W+ FD YNLW TFT
Sbjct 6046 YVPLRATNCITKCNIGGAVCSKHANLYRAYVESYNIFTQAGFNIWVPTTFDCYNLWQTFT 6105
Query 6427 R--LQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAF 6484
LQ LEN+A+NVVNKG F G GE PV+I + V+ + D +F NKT+LP N+AF
Sbjct 6106 EVNLQGLENIAFNVVNKGSFVGADGELPVAISGDKVFVRDGNTDNLVFVNKTSLPTNIAF 6165
Query 6485 ELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESA 6544
EL+AKR + P + IL NLGV V+WDY+ E P T VC TD A E
Sbjct 6166 ELFAKRKVGLTPPLSILKNLGVVATYKFVLWDYEAERPLTSFTKSVCGYTDFA----EDV 6221
Query 6545 CSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKT- 6603
C+ +D ++G + F + N VL + +VK T K +N L G ++ T
Sbjct 6222 CTC----YDNSIQGSYERFTLSTNAVLFSATAVK--TGGKSLPAIKLNFGMLNGNAIATV 6275
Query 6604 --------QFNYFKKV--DGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQR 6653
N+F V DG + ++TQ R+L+DF PRS ME DFL + + FIQ+
Sbjct 6276 KSEDGNIKNINWFVYVRKDGKPVDHYDGFYTQGRNLQDFLPRSTMEEDFLNMDIGVFIQK 6335
Query 6654 YKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPM-DSTVKNYFITDA 6712
Y LE + FEH+VYGD S LGGLHL+I + S+ LK E+F+ D T+K +T
Sbjct 6336 YGLEDFNFEHVVYGDVSKTTLGGLHLLISQVRLSKMGILKAEEFVAASDITLKCCTVTYL 6395
Query 6713 QTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYP 6772
SSK VC+ +DLLLDDFV ++KS DL+V+SKV +V ID +MLWCKD V TFYP
Sbjct 6396 NDPSSKTVCTYMDLLLDDFVSVLKSLDLTVVSKVHEVIIDNKPWRWMLWCKDNAVATFYP 6455
Query 6773 KLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTL 6832
+LQ+++ W+ G +MP +YK QRM LE C+L NYG +P GIM NV KYTQLCQY N+
Sbjct 6456 QLQSAE-WKCGYSMPGIYKTQRMCLEPCNLYNYGAGLKLPSGIMFNVVKYTQLCQYFNST 6514
Query 6833 TLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCAT 6892
TL VP+NMRV+H GAGSD GVAPGTAVL++WLP ++VD+D+ D+VSDAD ++ GDCAT
Sbjct 6515 TLCVPHNMRVLHLGAGSDYGVAPGTAVLKRWLPHDAIVVDNDVVDYVSDADFSVTGDCAT 6574
Query 6893 VHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWN 6952
V+ +K+DL+ISDMYD RTK + EN SKEGFFTY+ GFI +KLA+GGSIA+K+TE+SWN
Sbjct 6575 VYLEDKFDLLISDMYDGRTKAIDGENVSKEGFFTYINGFICEKLAIGGSIAIKVTEYSWN 6634
Query 6953 ADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQ--IDGYTMHANYIFWRNTN 7010
LY+L+ FS+WT F T+VN SSSEAF++G NYLG + IDG +HANY+FWRN+
Sbjct 6635 KKLYELVQRFSFWTMFCTSVNTSSSEAFVVGINYLGDFAQGPFIDGNIIHANYVFWRNST 6694
Query 7011 PIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDIL 7070
+ LS S+ D+SKF K + T V+ LK++ IN+M+ SL+ G+L++R N + + S+ L
Sbjct 6695 VMSLSYNSVLDLSKFNCKHKATVVVQLKDSDINEMVLSLVRSGKLLVRGNGKCLSFSNHL 6754
Query 7071 VN 7072
V+
Sbjct 6755 VS 6756
Score = 87.0 bits (214), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 66/196 (34%), Positives = 99/196 (51%), Gaps = 10/196 (5%)
Query 993 PEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGA 1052
P+ E +E +N F + DNVA D+ + IVNAAN +L HGGG+A A
Sbjct 1262 PKEEFVVKEKLNAFL----VHDNVAFYQGDVDTVVNGVDFDFIVNAANENLAHGGGLAKA 1317
Query 1053 LNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAA 1112
L+ T G +Q+ S ++I L G + VG ++ +L + +VVGP E L+KA
Sbjct 1318 LDVYTKGKLQRLSKEHIGLAGKVKVGTGVMVECDSL--RIFNVVGPRKGKHERDLLIKAY 1375
Query 1113 YENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT---QVYIAVNDKALYEQVVMDYL 1169
N Q L P+LS GIFG K SL+V + T +V++ + + + + L
Sbjct 1376 NTINNEQGTPLTPILSCGIFGIKLETSLEVLLDVCNTKEVKVFVYTDTEVCKVKDFVSGL 1435
Query 1170 DNLKPRVEAPKQEEPP 1185
N++ +VE PK E P
Sbjct 1436 VNVQ-KVEQPKIEPKP 1450
Score = 68.2 bits (165), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 84/340 (25%), Positives = 139/340 (41%), Gaps = 32/340 (9%)
Query 1537 LSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFF 1596
L E K I + T D N+H V ++ QQ G D++ P + +
Sbjct 1595 LKAAEAKVITIKVTEDGVNVHDVTVTTDKSFEQQVGVIADKDKDLSGAVPSDLNTSELLT 1654
Query 1597 VLPSDDTLRSEAFE---YYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYL 1653
D + F+ + T+D S Y SA+ V G+ +K +DNNC++
Sbjct 1655 KAIDVDWVEFYGFKDAVTFATVDHSAFA-YESAV----------VNGIRVLKTSDNNCWV 1703
Query 1654 SSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLL 1713
++V +ALQ + F + L A+ + GD F A + + G+ GD +T+T L
Sbjct 1704 NAVCIALQYSKPHFISQGLDAAWNKFVLGDVEIFVAFVYYVARLMKGDKGDAEDTLTKLS 1763
Query 1714 QH-ANLESAKRVLNVVCKHCGQK-TTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDAT 1771
++ AN + C C K ++ + + + ++ D ++ G CV G
Sbjct 1764 KYLANEAQVQLEHYSSCVECDAKFKNSVASINSAIVCASVKRDGVQVGY---CVHGIKYY 1820
Query 1772 QYLVQQESSFVMMSA----PPAEYKLQQGTFLCANEYTGNYQCGHYT-HITAKETLYRID 1826
+ +++S P A+ +L G A ++G GHYT + TAK+++Y D
Sbjct 1821 SRVRSVRGRAIIVSVEQLEPCAQSRLLSGVAYTA--FSGPVDKGHYTVYDTAKKSMY--D 1876
Query 1827 GAHLTKMSEYKGPVTDVF----YKETSYTTTIKPVSYKLD 1862
G K VT V Y T KPV +LD
Sbjct 1877 GDRFVKHDLSLLSVTSVVMVGGYVAPVNTVKPKPVINQLD 1916
Score = 49.7 bits (117), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 61/266 (23%), Positives = 109/266 (41%), Gaps = 20/266 (8%)
Query 1635 FPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAY 1694
F ++ GL +K DNNC+++SV+L +Q + A+Q + G A
Sbjct 1038 FEELNGLKILKQLDNNCWVNSVMLQIQLTGILDGDYAMQ----FFKMGRVAKMIERCYTA 1093
Query 1695 SNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYD 1754
G +GDV M LL+ +L + V++ C C +G AV++ T +
Sbjct 1094 EQCIRGAMGDVGLCMYRLLK--DLHTGFMVMDYKCS-CTSGRLEESG--AVLFC-TPTKK 1147
Query 1755 NLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHY- 1813
G + C R T +Q FV P +C++ + G CGHY
Sbjct 1148 AFPYGTCLNCNAPRMCTIRQLQGTIIFVQQKPEPVNPVSFVVKPVCSSIFRGAVSCGHYQ 1207
Query 1814 THITAKETLYRIDGAHLTKMSEYKG-PVTDVFYKETSYTT----TIKPVSYKLDGVTYTE 1868
T+I ++ +DG + K+ + + + K+ Y ++ P+ +D E
Sbjct 1208 TNIYSQNLC--VDGFGVNKIQPWTNDALNTICIKDADYNAKVEISVTPIKNTVDTTPKEE 1265
Query 1869 --IEPKLDGYYKKDNAYYTEQPIDLV 1892
++ KL+ + DN + + +D V
Sbjct 1266 FVVKEKLNAFLVHDNVAFYQGDVDTV 1291
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 4194 bits (10878), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2234/4899 (46%), Positives = 3042/4899 (62%), Gaps = 203/4899 (4%)
Query 2240 CNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILG 2299
CNG + Y NSS + + C S C CL+ D L + + +QVT +K D
Sbjct 1921 CNGAVQAYKNSSFIKSA-VCGNSILCKACLASYDELADF---QHLQVTWD-FKSDPLWNR 1975
Query 2300 LAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWF-------IISIVQMA 2352
L L+Y F F + ++ F YF S ++ N WL +F + +V
Sbjct 1976 LVQ---LSYFAFLAVFG----NNYVRCFLMYFVSQYL-NLWLSYFGYVEYSWFLHVVNFE 2027
Query 2353 PVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFY 2412
+SA + + K HI+ C++ +C C + R TR+ +VNG ++ Y
Sbjct 2028 SISAEFVIVVIVVKAVLALK---HIVFACSNPSCKTCSRTARQTRIPIQVVVNGSMKTVY 2084
Query 2413 VYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVA 2472
V+ANG FCK HN+ C NCD++ +TFI DE+ RDLS K+ + TD+S V V
Sbjct 2085 VHANGTGKFCKKHNFYCKNCDSYGFENTFICDEIVRDLSNSVKQTVYATDRSHQEVTKVE 2144
Query 2473 VKNGALHLY---------FDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGK 2523
+G Y +D +K + L + LD+ + GS NV
Sbjct 2145 CSDGFYRFYVGDEFTSYDYDVKHKKYSSQEVLKSMLLLDDFIVYSPSGSALANV------ 2198
Query 2524 SKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPM 2583
++A VY+SQL+ +PI +++ L+ D+ S + +F+A + +F+V +
Sbjct 2199 --------RNACVYFSQLIGKPIKIVNSDLLEDL--SVDFKGALFNAKKNVIKNSFNVDV 2248
Query 2584 EKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVT 2643
+ K L E + L+ STF A +H + +T
Sbjct 2249 SECKNL-----DECYRACNLNVSFSTFEMAVNN------------------AHRFGILIT 2285
Query 2644 GDSCNNFMLTYNK--VENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQ 2701
S NNF + K ++ D+G C+ +A+ +NA+V S++W +D+ +LS
Sbjct 2286 DRSFNNFWPSKVKPGSSGVSAMDIGKCMTSDAKIVNAKVLTQRGKSVVWLSQDFAALSST 2345
Query 2702 LRKQIRSAAKKNNIPFRLTCATTRQVVNV----ITTKISLKGGKIVSTCFKLMLKATLLC 2757
+K + + + F LT ++ T +S K G + + +L
Sbjct 2346 AQKVLVKTFVEEGVNFSLTFNAVGSDDDLPYERFTESVSPKSGSGFFDVITQLKQIVILV 2405
Query 2758 VLAALVC-----YIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFD 2812
+ +C Y V + +GY Y I++G+ + T C N + GF
Sbjct 2406 FVFIFICGLCSVYSVATQSYIESAEGYD-----YMVIKNGIVQPFDDTISCVHNTYKGFG 2460
Query 2813 AWFSQRGGSYKN-DKSCP-VVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVG 2870
WF + G KSCP VV + E +P +P V +I G L F V
Sbjct 2461 DWFKAKYGFIPTFGKSCPIVVGTVFDLENMRPIPDVPAYV--SIVGRSLVFAINAAFGVT 2518
Query 2871 NICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTR 2930
N+CY + D CV CT +G + YC L+EG+ YS+L PD
Sbjct 2519 NMCYDHTGNAVSKDSYFDTCVFNTACTTLT-GLGGTIVYCAKQGLVEGAKLYSDLMPDYY 2577
Query 2931 YVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRA 2990
Y G++++ P +R V T YCR G C S+ G C +V +NE
Sbjct 2578 YEHASGNMVKLPAIIRGLGLRFVKTQATTYCRVGECIDSKAGFCFGGDNWFVYDNEFG-- 2635
Query 2991 LSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGE 3050
+G CG + N+F + + S +++ IIA L Y +KF+++FG+
Sbjct 2636 -NGYICGNSVLGFFKNVFKLFNSNMSVVATSGAMLVNIIIACLAIAMCYGVLKFKKIFGD 2694
Query 3051 YNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQ--WFAM 3108
++ ++ L+ + V +F +Y++ Y ++ T +++ L +
Sbjct 2695 CTFLIVM-IIVTLVVNNVSYFVTQNTFFMIIYAIVY----YFITRKLAYPGILDAGFIIA 2749
Query 3109 FSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMY 3167
+ + P+++ Y+ F + +F G F FE AA+ TF+++ Y
Sbjct 2750 YINMAPWYVITAYILVFLYDSLPSLFKLKVSTN-LFEGDKFVGNFESAAMGTFVIDMRSY 2808
Query 3168 LKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLY 3227
+ + T + + Y +NKYKY++G++ YR A HL KAL D+S + D+LY
Sbjct 2809 ETIVNST--SIARIKSYANSFNKYKYYTGSMGEADYRMACYAHLGKALMDYSVNRTDMLY 2866
Query 3228 QPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAE 3287
PP S+ S LQSG RKMA PSG VE C+V+V+ G LNGLWL D V CPRHVI +
Sbjct 2867 TPPTVSVNST-LQSGLRKMAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVIASDT 2925
Query 3288 DMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQ 3347
+ NYE+ + H+F V NV L V+ + L LKV+ NP TP++KF I+
Sbjct 2926 TRV-INYENEMSSVRLHNFSVSKNNVFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIK 2984
Query 3348 PGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMEL 3407
G++F++LACY G P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL
Sbjct 2985 AGESFNILACYEGCPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLEL 3044
Query 3408 PTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTL 3467
G H G++ EG+ YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + +L
Sbjct 3045 GNGSHVGSNFEGEMYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSL 3104
Query 3468 NDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTIL 3527
+N A ++ L+ D L+A+TG +V + ++ L G GRTIL L
Sbjct 3105 ESYNTWAKTNSFTELSS--TDAFSMLAAKTGQSVEKLLDSIVRL-NKGFGGRTILSYGSL 3161
Query 3528 EDEFTPFDVVRQCSGVTFQ-GKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFF----F 3582
DEFTP +V+RQ GV Q GK K + + ++T +T L W FF F
Sbjct 3162 CDEFTPTEVIRQMYGVNLQAGKVK-----SFFYPIMTAMTILFAF-----WLEFFMYTPF 3211
Query 3583 VYEN-AFLPFTLGIMAIAACAMLL-VKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRI 3640
+ N F+ L + + + + +KHK F F+LPS+ V N+ + S+ +
Sbjct 3212 TWINPTFVSIVLAVTTLISTVFVSGIKHKMLFFMSFVLPSVILVTAHNL-FWDFSYYESL 3270
Query 3641 MTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVY---K 3697
+ +E +T ++ ++ ++ + + R ++ W + V T++
Sbjct 3271 QSIVENTNTMFLPVDMQGVMLTVFCFIVFVTYSVRFF---TCKQSWFSLAVTTILVIFNM 3327
Query 3698 VYYGNALDQA----------ISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLF 3747
V D+ ++M +++S+T+ VV +A IV VCV P F
Sbjct 3328 VKIFGTSDEPWTENQIAFCFVNMLTMIVSLTTKDWMVVIASYRIAYYIV-VCV--MPSAF 3384
Query 3748 ITG-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL 3806
++ ++CI +VY GY CCY+G+ +NR+ +T GVY + VS E +YM + L
Sbjct 3385 VSDFGFMKCISIVYMACGYLFCCYYGILYWVNRFTCMTCGVYQFTVSAAELKYMTANNLS 3444
Query 3807 PPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA 3866
PK++ DA L+ KL+G+GGK IK++TVQSK++++KCT+VVLL +L ++ VES+SK W
Sbjct 3445 APKNAYDAMILSAKLIGVGGKRNIKISTVQSKLTEMKCTNVVLLGLLSKMHVESNSKEWN 3504
Query 3867 QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFS 3926
CV LHN+I L D EK+++L++ LS D++ L E +N LQ++AS ++
Sbjct 3505 YCVGLHNEINLCDDPEIVLEKLLALIAFFLSKHNTCDLSELIESYFENTTILQSVASAYA 3564
Query 3927 SLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM 3986
+LPS+ A A+ E+A N S +LK+L K+ N+AKS+F+R+A++Q+KL+KMA+QA
Sbjct 3565 ALPSWIALEKARADLEEAKKNDVSPQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAA 3624
Query 3987 TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK 4046
MYK+AR+ D+++K+ SAM ++LF ML+KLD ++N II+ AR+G +PL+IIP +A +
Sbjct 3625 ASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATR 3684
Query 4047 LMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVT 4106
L+V+ P + N YA A+W I +V DA+ V L E+ N NL WPL +T
Sbjct 3685 LVVITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAANELNLTWPLSIT 3744
Query 4107 ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQ 4166
R KLQNNE+ P L++ + A T + A + G F+ A ++
Sbjct 3745 CERT---TKLQNNEIMPGKLKERAVRASATLDGEAFGSGKALMASESGKSFMYAFIASDN 3801
Query 4167 DLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAAT 4226
+LK+ ++ ++ I ELE P RF D GP+VKYLYF+K LN L RG VLG + AT
Sbjct 3802 NLKYVKWESNNDI--IPIELEAPLRFYVDGANGPEVKYLYFVKNLNTLRRGAVLGYIGAT 3859
Query 4227 VRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT 4286
VRLQAG TE P+NS++L+ CAF+ DPAKAY D + G QP+ NCVKML G G A+T
Sbjct 3860 VRLQAGKPTEHPSNSSLLTLCAFSPDPAKAYVDAVKRGMQPVNNCVKMLSNGAGNGMAVT 3919
Query 4287 VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTV 4346
EAN Q+S+GGAS C+YCRCH++HP G C KGK+VQIPT DP+ F + N V
Sbjct 3920 NGVEANTQQDSYGGASVCIYCRCHVEHPAIDGLCRYKGKFVQIPTG-TQDPIRFCIENEV 3978
Query 4347 CTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDI 4406
C VCG W GC CD R + ++LNRV G SAARL PC GT D V RAFDI
Sbjct 3979 CVVCGCWLNNGCMCD--RTSMQSFTVDQSYLNRVRGSSAARLEPC-NGTDPDHVSRAFDI 4035
Query 4407 YNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVA 4466
YN+ VA KFLKTNC RF+ D+ D+Y++VKR T + HE+ YN +KD AVA
Sbjct 4036 YNKDVACIGKFLKTNCSRFRNLDKH----DAYYIVKRCTKTVMDHEQVCYNDLKDSGAVA 4091
Query 4467 VHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYF 4526
HDFF ++ +++R+ LTKYTM DL YA+R+FDE NC+ LKEILVT C +++F
Sbjct 4092 EHDFFTYKEGRCEFGNVARRNLTKYTMMDLCYAIRNFDEKNCEVLKEILVTVGACTEEFF 4151
Query 4527 NKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWY 4586
KDW+D VEN I VYA LG V ++LK V FCDA+ + G +GV+TLDNQDLNGN+Y
Sbjct 4152 ENKDWFDPVENEAIHEVYAKLGPIVANAMLKCVAFCDAIVEKGYIGVITLDNQDLNGNFY 4211
Query 4587 DFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADL-AKPLIKWDLLKYDFT 4645
DFGDFV+ APG G V SYYS +MP++ +T L +E+ + +D+ ++DLL YDFT
Sbjct 4212 DFGDFVKTAPGFGCACVTSYYSYMMPLMGMTSCLESENFVKSDIYGSDYKQYDLLAYDFT 4271
Query 4646 EERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVD 4705
E + LF +YFKYWD+TYHPNC +C D CI+HCANFN LFS P T+FGPLVRK+ +D
Sbjct 4272 EHKEYLFQKYFKYWDRTYHPNCSDCTSDECIIHCANFNTLFSMTIPMTAFGPLVRKVHID 4331
Query 4706 GVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCF 4765
GVP VV+ GYHF++LG+V N DV L + +LS +LL + DP + AS LLD+RT CF
Sbjct 4332 GVPVVVTAGYHFKQLGIVWNLDVKLDTMKLSMTDLLRFVTDPTLLVASSPALLDQRTVCF 4391
Query 4766 SVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYY 4825
S+AAL+ + +QTVKPG+FNKDFYDF +GFF+EGS + LKHFFFAQ G AA++D++YY
Sbjct 4392 SIAALSTGITYQTVKPGHFNKDFYDFITERGFFEEGSELTLKHFFFAQGGEAAMTDFNYY 4451
Query 4826 RYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYY 4885
RYN T+ DI Q FV ++V KYF+CYDGGCINA +V+V N DKSAG+P NK+GKARLYY
Sbjct 4452 RYNRVTVLDICQAQFVYKIVGKYFECYDGGCINAREVVVTNYDKSAGYPLNKFGKARLYY 4511
Query 4886 DSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLL 4945
+++SYE+QDALFA TKRNV+PT+TQMNLKYAIS K RARTV GVS+ STMT RQ+HQK L
Sbjct 4512 ETLSYEEQDALFALTKRNVLPTMTQMNLKYAISGKARARTVGGVSLLSTMTTRQYHQKHL 4571
Query 4946 KSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASL 5005
KSIAATR ATVVIG++KFYGGW NMLK + DV+ LMGWDYPKCDRA+PNM+R+ +++
Sbjct 4572 KSIAATRNATVVIGSTKFYGGWDNMLKNLMRDVDNGCLMGWDYPKCDRALPNMIRMASAM 4631
Query 5006 VLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNI 5065
+L KH CC + RFYRL+NE AQVL+E+V C G Y KPGGT+SGD TTAYANS FNI
Sbjct 4632 ILGSKHVGCCTHNDRFYRLSNELAQVLTEVVHCTGGFYFKPGGTTSGDGTTAYANSAFNI 4691
Query 5066 CQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMM 5125
QAV+ANVN LL D N + V+++Q ++Y+ YR+ +D EFV E+++YLRKHFSMM
Sbjct 4692 FQAVSANVNKLLGVDSNACNNVTVKSIQRKIYDNCYRSSSIDEEFVVEYFSYLRKHFSMM 4751
Query 5126 ILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQH 5185
ILSDD VVCYN +YA G VA I FKA LYYQNNVFMS +KCW E DL+ GPHEFCSQH
Sbjct 4752 ILSDDGVVCYNKDYADLGYVADINAFKATLYYQNNVFMSTSKCWVEPDLSVGPHEFCSQH 4811
Query 5186 TMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQE 5245
T+ + D YLPYPDPSRIL AG FVDDIVKTD +M+ER+VSLAIDAYPLTKHP
Sbjct 4812 TLQIVGPDGDYYLPYPDPSRILSAGVFVDDIVKTDNVIMLERYVSLAIDAYPLTKHPKPA 4871
Query 5246 YADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGA 5305
Y VF+ L +++ L L +LD +SV + + ++W EFY ++Y TVLQA G
Sbjct 4872 YQKVFYTLLDWVKHLQKNLNAGVLDSFSVTMLEEGQDKFWSEEFYASLYEKSTVLQAAGM 4931
Query 5306 CVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLY 5365
CV+C SQT LRCG C+RRP LC KC YDHV+ T HK ++S+ PYVC+ GC+V DVT+L+
Sbjct 4932 CVVCGSQTVLRCGDCLRRPLLCTKCAYDHVMGTKHKFIMSITPYVCSFNGCNVNDVTKLF 4991
Query 5366 LGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILAN 5425
LGG+SYYC +HKP +SFPLCANG VFGLYK++ VGS+ V DFN +A DWTN DY LAN
Sbjct 4992 LGGLSYYCMNHKPQLSFPLCANGNVFGLYKSSAVGSEAVEDFNKLAVSDWTNVEDYKLAN 5051
Query 5426 TCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTG 5485
E LK+FAAET+KA EE+ K Y A ++EV+ +E+ L WE K +PPLNRN VFT
Sbjct 5052 NVKESLKIFAAETVKAKEESVKSEYAYAVLKEVIGPKEIVLQWEASKTKPPLNRNSVFTC 5111
Query 5486 YRVTKNSKVQIGEYTFEKGDYG-DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQ 5544
++++K++K+Q+GE+ FE+ +YG D+V Y+ T+TYKL G FVLTSH V PL AP LV Q
Sbjct 5112 FQISKDTKIQLGEFVFEQSEYGSDSVYYKSTSTYKLTPGMIFVLTSHNVSPLKAPILVNQ 5171
Query 5545 EHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSAR 5604
E Y I+ LYP NI++ +++ V YQ +G QK++T+QGPPG+GKSH IGL LYYP AR
Sbjct 5172 EKYNTISKLYPVFNIAEAYNTLVPYYQMIGKQKFTTIQGPPGSGKSHCVIGLGLYYPQAR 5231
Query 5605 IVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNAL 5664
IVYTACSHAAVDALCEKA K +D+CSRIIP R RV+C+ FK N+T QY+FCTVNAL
Sbjct 5232 IVYTACSHAAVDALCEKAAKNFNVDRCSRIIPQRIRVDCYTGFKPNNTNAQYLFCTVNAL 5291
Query 5665 PETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFN 5724
PE + DIVV DE+SM TNYDLSV+N+RL KH VY+GDP QLPAPRTL+ KG L+P+ +N
Sbjct 5292 PEASCDIVVVDEVSMCTNYDLSVINSRLSYKHIVYVGDPQQLPAPRTLINKGVLQPQDYN 5351
Query 5725 SVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHD 5784
V + M T+GPD+FL C RCPAEIV TVSALVY+NK +S QCFKMF KG + +
Sbjct 5352 VVTKRMCTLGPDVFLHKCYRCPAEIVKTVSALVYENKFVPVNPESKQCFKMFVKGQVQIE 5411
Query 5785 VSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDY 5844
+S+IN Q+ VV+ FL NP WRKAVFISPYNSQN VA ++LGL TQTVDS+QGSEYDY
Sbjct 5412 SNSSINNKQLEVVKAFLAHNPKWRKAVFISPYNSQNYVARRLLGLQTQTVDSAQGSEYDY 5471
Query 5845 VIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAE 5904
VI+TQT++T H+ NVNRFNVAITRAK+GILCIM DR +Y+ L F L+ + LQA+
Sbjct 5472 VIYTQTSDTQHATNVNRFNVAITRAKVGILCIMCDRTMYENLDFYELKDSK---IGLQAK 5528
Query 5905 NVT-GLFKDCSKIITGLHPTQAPTHLSVDIKFKT-EGLCVDIPGIPKDMTYRRLISMMGF 5962
T GLFKDCSK + P A T++S+ FKT +GL V+I KD+ Y +IS MGF
Sbjct 5529 PETCGLFKDCSKSEQYIPPAYATTYMSLSDNFKTSDGLAVNIG--TKDVKYANVISYMGF 5586
Query 5963 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAV 6022
+ + GY +F TR+ A+R+VRAW+GFDVEG H D VGTN+PLQLGFS GV+ V
Sbjct 5587 RFEANIPGYHTLFCTRDFAMRNVRAWLGFDVEGAHVCGDNVGTNVPLQLGFSNGVDFVVQ 5646
Query 6023 PTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDR 6082
G V TE V A+ PPG+QF HLIPLM KG PW++VR +IVQM+ D GLSD
Sbjct 5647 TEGCVITEKGNSIEVVKARAPPGEQFAHLIPLMRKGQPWHIVRRRIVQMVCDYFDGLSDI 5706
Query 6083 VVFVLWAHGFELTSMKYFVKIG-PERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNP 6141
++FVLWA G ELT+M+YFVKIG P++ C C K ATC+S+S YAC+ H++G DY+YNP
Sbjct 5707 LIFVLWAGGLELTTMRYFVKIGRPQK--CECGKSATCYSSSQSVYACFKHALGCDYLYNP 5764
Query 6142 FMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPII 6201
+ ID+QQWG+TG+L NH + C +H N HVAS DAIMTRCLA+H+CFVKRVDWS+ YP I
Sbjct 5765 YCIDIQQWGYTGSLSMNHHEVCNIHRNEHVASGDAIMTRCLAIHDCFVKRVDWSIVYPFI 5824
Query 6202 GDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDK 6261
+E ++N A R VQ V+K+AL +HD+GNPK I+C + W YD P ++
Sbjct 5825 DNEEKINKAGRIVQSHVMKAALKIFNPAAIHDVGNPKGIRCA-TTPIPWFCYDRDPINN- 5882
Query 6262 AYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSL 6321
+ L Y Y H +G+ LFWNCNVD YP +IVCRFDTR S L+L GC+GG+L
Sbjct 5883 --NVRCLDYDYMVHGQ--MNGLMLFWNCNVDMYPEFSIVCRFDTRTRSKLSLEGCNGGAL 5938
Query 6322 YVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNL 6381
YVN HAFHTPA+D+ AF LK +PFFYY DS CE V +YVPLKS CIT+CN+
Sbjct 5939 YVNNHAFHTPAYDRRAFAKLKPMPFFYYDDSNCE----LVDGQPNYVPLKSNVCITKCNI 5994
Query 6382 GGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTR---LQSLENVAYNV 6438
GGAVC+ HA YR Y++ YN+ + AGF++W + FDTY LW+ F LQSLENVA+NV
Sbjct 5995 GGAVCKKHAALYRAYVEDYNIFMQAGFTIWCPQNFDTYMLWHGFVNSKALQSLENVAFNV 6054
Query 6439 VNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEI 6498
V KG F G G+ P ++I + + + D IF NKT+LP NVAFEL+AKR + P +
Sbjct 6055 VKKGAFTGLKGDLPTAVIADKIMVRDGPTDKCIFTNKTSLPTNVAFELYAKRKLGLTPPL 6114
Query 6499 KILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEG 6558
IL NLGV V+WDY+ E P T VC+ TD+ S + FD + G
Sbjct 6115 TILRNLGVVATYKFVLWDYEAERPFSNFTKQVCSYTDLD--------SEVVTCFDNSIAG 6166
Query 6559 QVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNG--VTLIGESVKTQFNYFKKVDGIIQ 6616
+ F R+ VLI+ +VKGL+ K +N V+ +G T + Y +K ++
Sbjct 6167 SFERFTTTRDAVLISNNAVKGLSAIK-LQYGLLNDLPVSTVGNKPVTWYIYVRKNGEYVE 6225
Query 6617 QLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGG 6676
Q+ ++Y+TQ R E FKPRS ME DFL + FIQ+Y LE Y FEH+V+GD S +GG
Sbjct 6226 QI-DSYYTQGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHVVFGDVSKTTIGG 6284
Query 6677 LHLMIGLAKRSQDSPLKLEDFI-PMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEII 6735
+HL+I + ++ +++F+ DST+K+ IT A SSK VC+ +D+LLDDFV II
Sbjct 6285 MHLLISQVRLAKMGLFSVQEFMNNSDSTLKSCCITYADDPSSKNVCTYMDILLDDFVTII 6344
Query 6736 KSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRM 6795
KS DL+V+SKVV V +D +MLWC++ H++TFYP+LQ+++ W PG +MP LYK+QRM
Sbjct 6345 KSLDLNVVSKVVDVIVDCKAWRWMLWCENSHIKTFYPQLQSAE-WNPGYSMPTLYKIQRM 6403
Query 6796 LLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAP 6855
LE+C+L NYG +P GI NV KYTQLCQYLNT TL VP+ MRV+H GA GVAP
Sbjct 6404 CLERCNLYNYGAQVKLPDGITTNVVKYTQLCQYLNTTTLCVPHKMRVLHLGAAGASGVAP 6463
Query 6856 GTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVT 6915
G+ VLR+WLP +LVD+DL D+VSDAD ++ GDC +++ +K+DL++SD+YD TK +
Sbjct 6464 GSTVLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTSLYIEDKFDLLVSDLYDGSTKSID 6523
Query 6916 KENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNAS 6975
EN SK+GFFTY+ GFIK+KL+LGGS+A+KITE SWN DLY+L+ F +WT F T+VN S
Sbjct 6524 GENTSKDGFFTYINGFIKEKLSLGGSVAIKITEFSWNKDLYELIQRFEYWTVFCTSVNTS 6583
Query 6976 SSEAFLIGANYLGK--PKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTA 7033
SSE FLIG NYLG K +DG MHANYIFWRN+ + LS S+ D KF +
Sbjct 6584 SSEGFLIGINYLGPYCDKAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFKCRCNNAL 6643
Query 7034 VMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
+++LKE ++N+M+ LL KG+L+IR N +++ + VN
Sbjct 6644 IVNLKEKELNEMVIGLLRKGKLLIRNNGKLLNFGNHFVN 6682
Score = 66.2 bits (160), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 72/276 (26%), Positives = 118/276 (43%), Gaps = 28/276 (10%)
Query 969 ETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQF--TGYLKLTDNVAIKCVDIVKE 1026
+ +VE+ E++ +++ E E P ++ + F G L ++ ++
Sbjct 1288 QEFKVEKVEQQPIVEENKSSIEKEEIQSPKNDDLILPFYKAGKLSFYQGALDVLINFLE- 1346
Query 1027 AQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGH 1086
P VIVNAAN LKH GGVA A++ T G + + S DY+K N + G +
Sbjct 1347 -----PDVIVNAANGDLKHMGGVARAIDVFTGGKLTERSKDYLKKNKSIAPGNAVFFENV 1401
Query 1087 NLAKKCLHVVGP-NLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQ 1145
L+ VGP N ++ + +L + +L PL+S GIF + SLQ ++
Sbjct 1402 IEHLSVLNAVGPRNGDSRVEAKLCNVYKAIAKCEGKILTPLISVGIFNVRLETSLQCLLK 1461
Query 1146 TVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPP--NTEDSKTEEKSVVQKPVD 1203
T VND+ L V Y D + +E P TED+ E+ V
Sbjct 1462 T--------VNDRGLN---VFVYTDQERQTIENFFSCSIPVNVTEDNVNHERVSVSFDKT 1510
Query 1204 VKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKL 1239
++K T + + K +TN+L D+ K+
Sbjct 1511 YGEQLKG------TVVIKDKDVTNQLPSAFDVGQKV 1540
Score = 47.0 bits (110), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 71/287 (25%), Positives = 115/287 (40%), Gaps = 31/287 (11%)
Query 1544 TIKVFTTVDNTNLHTQLVDMSMTYGQQF-GPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
+I V T DN N V TYG+Q G + DVT P G+ V+ + D
Sbjct 1488 SIPVNVTEDNVNHERVSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQK--VIKAID 1545
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSI--KWADNNCYLSSVLLAL 1660
+ +Y D + SA +H +KF V I K DNNC+++++ LAL
Sbjct 1546 I---DWQAHYGFRDAAAF----SASSH-DAYKFEVVTHSNFIVHKQTDNNCWINAICLAL 1597
Query 1661 QQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLES 1720
Q+L+ ++ P ++ + F ++ S GE GD E M H L
Sbjct 1598 QRLKPQWKFPGVRGLWNEFLERKTQGFVHMLYHISGVKKGEPGDA-ELMLHKLGDLMDND 1656
Query 1721 AKRVL--NVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKT-GVSIPCVCGRDATQYLVQQ 1777
+ ++ C C + VE ++G + L G CV G + Q
Sbjct 1657 CEIIVTHTTACDKCAK-------VEK--FVGPVVAAPLAIHGTDETCVHGVSVNVKVTQI 1707
Query 1778 ESSFVMMS--APPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETL 1822
+ + + S P L+ ++C Y+G+ + GHYT+ + L
Sbjct 1708 KGTVAITSLIGPIIGEVLEATGYIC---YSGSNRNGHYTYYDNRNGL 1751
Score = 45.4 bits (106), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 53/205 (26%), Positives = 85/205 (41%), Gaps = 15/205 (7%)
Query 1633 WKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALIL 1692
+K + G +K DNNC++++ LQ + FN EA+ + + GD +F L
Sbjct 1075 FKTTNLNGKIILKQGDNNCWINACCYQLQAFDF-FN----NEAWEKFKKGDVMDFVNLCY 1129
Query 1693 AYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLS 1752
A + G GD + +L + +AK VL C CG+K L E ++ T
Sbjct 1130 AATTLARGHSGDAEYLLELMLN--DYSTAKIVLAAKCG-CGEKEIVL---ERAVFKLTPL 1183
Query 1753 YDNLKTGVSIPCVCGRDATQYLVQQESSFV--MMSAPPAEYKLQQGTFLCANEYTGNYQC 1810
++ GV C+ V+ FV ++S E + A YTG Q
Sbjct 1184 KESFNYGVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHA-VYTGTTQN 1242
Query 1811 GHYTHITAKETLYRIDGAHLTKMSE 1835
GHY + E Y +DG + + +
Sbjct 1243 GHYM-VDDIEHGYCVDGMGIKPLKK 1266
Score = 37.7 bits (86), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 52/256 (20%), Positives = 100/256 (39%), Gaps = 21/256 (8%)
Query 604 GLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV--K 661
GL+ + + W G + E + L+ K +E++ L T F IV K
Sbjct 380 GLLFKKTPWFVQKCGALFVDAWKVVEELCGSLTLT---YKQIYEVVASLCTSAFTIVNYK 436
Query 662 GQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC- 720
V + +KD V + V+ KA ++ +TIAG + + LG ++ + L +
Sbjct 437 PTFVVPDNRVKDLVDKCVKVLVKAFDVFTQIITIAGIEAKCFVLGAKYLLFNNALVKLVS 496
Query 721 --IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAI 778
I GK+Q L A + + + T +E + +++ + P + +
Sbjct 497 VKILGKKQKGLECAFFA---TSLVGATVNVTPKRTETATISLNKVDDVVAPGEGY----- 548
Query 779 VGTPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYK 838
+ + G M + + SP + TNNVF+ P + + D + +
Sbjct 549 ----IVIVGDMAFYKSGEYYFMMSSPNFVLTNNVFKAV-KVPSYDIVYDVDNDTKSKMIA 603
Query 839 NVRITFELDERVDKVL 854
+ +FE D +D +
Sbjct 604 KLGSSFEYDGDIDAAI 619
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 4173 bits (10822), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2233/4896 (46%), Positives = 3038/4896 (62%), Gaps = 197/4896 (4%)
Query 2240 CNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILG 2299
C+G + Y NSS V + + C S C CL+ D L + L+ YK D
Sbjct 1946 CSGSVQAYSNSSFVKS-EVCGNSILCKACLASYDELADFDHLQVSW----DYKSDPLWNR 2000
Query 2300 LAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWF-------IISIVQMA 2352
+ L+Y +F F + ++ YF S ++ N WL +F + +V
Sbjct 2001 VIQ---LSYFIFLAVFG----NNYVRCLLMYFVSQYL-NLWLSYFGYVKYSWFLHVVNFE 2052
Query 2353 PVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFY 2412
+S + + K HI C + +C C K R TR+ +VNG ++ Y
Sbjct 2053 SISVEFVIIVVVFKAVLALK---HIFLPCNNPSCKTCSKIARQTRIPIQVVVNGSMKTVY 2109
Query 2413 VYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVA 2472
V+ANG CK HN+ C NCD++ TFI DE+ RDLS K+ + TD+S V V
Sbjct 2110 VHANGTGKLCKKHNFYCKNCDSYGFDHTFICDEIVRDLSNSIKQTVYATDRSYQEVTKVE 2169
Query 2473 VKNGALHLY---------FDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGK 2523
+G Y +D +K + L LD+ N GS +V
Sbjct 2170 CTDGFYRFYVGEEFTAYDYDVKHKKYSSQEVLKTMFLLDDFIVYNPSGSSLASV------ 2223
Query 2524 SKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPM 2583
++ VY+SQL+ +PI +++ L+ D+ S + +F+A + +F+V +
Sbjct 2224 --------RNVCVYFSQLIGRPIKIVNSELLEDL--SVDFKGALFNAKKNVIKNSFNVDV 2273
Query 2584 EKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVT 2643
+ K L E K LD STF A +H + +T
Sbjct 2274 SECKNL-----EECYKLCNLDVTFSTFEMAINN------------------AHRFGILIT 2310
Query 2644 GDSCNNFMLTYNK--VENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQ 2701
S NNF + K ++ D+G C+ +A+ +NA+V S++W +D+ +LS
Sbjct 2311 DRSFNNFWPSKIKPGSSGVSAMDIGKCMTFDAKIVNAKVLTQRGKSVVWLSQDFSTLSST 2370
Query 2702 LRKQIRSAAKKNNIPFRLTCATTRQVVNV----ITTKISLKGGKIVSTCFKLMLKATLLC 2757
+K + + + F LT ++ T +S K G K LK C
Sbjct 2371 AQKVLVKTFVEEGVNFSLTFNAVGSDEDLPYERFTESVSAKSGSGFFDVLK-QLKQLFWC 2429
Query 2758 VLAALVCYIVMPVHTLSIHDGYTNEIIGYK--AIQDGVTRDIISTDDCFANKHAGFDAWF 2815
++ + Y + V++++ Y + GY I++GV + + +C N + GF WF
Sbjct 2430 LVLFITLYGLCSVYSVATQ-SYIDSAEGYDYMVIKNGVVQSFDDSINCVHNTYKGFAVWF 2488
Query 2816 SQRGGSYKN-DKSCPVVAAIITREIGFI--VPGLPGTVLRAINGDFLHFLPRVFSAVGNI 2872
+ G DKSCP+V + ++G + +P +P V A+ G L F V N+
Sbjct 2489 KAKHGFVPTFDKSCPIVLGTVF-DLGNMRPIPDVPAYV--ALVGRSLVFAINAAFGVTNV 2545
Query 2873 CY--TPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTR 2930
CY T + + + S F T CV + CT +G V YC L+EG+ YSEL PD
Sbjct 2546 CYDHTGAAVSKNSYFDT--CVFNSACTTLT-GIGGTVVYCAKQGLVEGAKLYSELLPDYY 2602
Query 2931 YVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRA 2990
Y G++++ P +R V T YCR G C S+ G C +V + E
Sbjct 2603 YEHASGNMVKIPAIIRSFGLRFVKTQATTYCRVGECTESQAGFCFGGDNWFVYDKEFG-- 2660
Query 2991 LSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGE 3050
G CG + N+F + + S +++A +IA L Y +KF+++FG+
Sbjct 2661 -DGYICGSSTLGFFKNVFALFNSNMSVVATSGAMLANIVIACLAIAVCYGVLKFKKIFGD 2719
Query 3051 YNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQ--WFAM 3108
+V ++ L+ + V +F VY++ Y ++ T +++ L +
Sbjct 2720 CTLLVVM-IIVTLVVNNVSYFVTQNTFFMIVYAIIY----YFTTRKLAYPGVLDAGFIIA 2774
Query 3109 FSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMY 3167
+ + P+++ +Y+ F + +F G F +FE AA+ TF+++ Y
Sbjct 2775 YLNMAPWYVLVLYIMVFLYDSLPSLFKLKVTTN-LFEGDKFVGSFESAAMGTFVIDMRSY 2833
Query 3168 LKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLY 3227
L + T L + Y +NKYKY++G++ YR A HL KAL D+S S D+LY
Sbjct 2834 ETLVNST--SLDRIKSYANSFNKYKYYTGSMGEADYRMACYAHLGKALMDYSVSRNDMLY 2891
Query 3228 QPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAE 3287
PP S+ S LQSG RKMA PSG VE C+V+V G LNGLWL D V CPRHVI +
Sbjct 2892 TPPTVSVNST-LQSGLRKMAQPSGVVEPCIVRVAYGNNVLNGLWLGDEVICPRHVIASDT 2950
Query 3288 DMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQ 3347
+ NYE+ L H+F + N L V+ + L LKV+ NP TP++KF ++
Sbjct 2951 SRV-INYENELSSVRLHNFSIAKNNAFLGVVSAKYKGVNLVLKVNQVNPNTPEHKFKSVR 3009
Query 3348 PGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMEL 3407
PG++F++LACY G P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL
Sbjct 3010 PGESFNILACYEGCPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGTLYFVYMHHLEL 3069
Query 3408 PTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTL 3467
G H G++LEG+ YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + TL
Sbjct 3070 GNGSHVGSNLEGEMYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMTL 3129
Query 3468 NDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTIL 3527
+N A ++ + D L+A+TG +V + + L G GRTIL L
Sbjct 3130 ESYNAWAKTNSFTEIVS--TDAFNMLAAKTGYSVEKLLECIVRL-NKGFGGRTILSYGSL 3186
Query 3528 EDEFTPFDVVRQCSGVTFQ-GKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFF----F 3582
DEFTP +V+RQ GV Q GK K I +T++ IL W FF F
Sbjct 3187 CDEFTPTEVIRQMYGVNLQSGKVKSI--------FYPMMTAIAILFAF--WLEFFMYTPF 3236
Query 3583 VYEN-AFLPFTLGIMAIAACAMLL-VKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRI 3640
+ N F+ L I + + ++ +KHK F F++PS+ N+V+ ++ +
Sbjct 3237 TWINPTFVSVVLAITTLVSVLLVAGIKHKMLFFMSFVMPSVILATAHNVVW-DMTYYESL 3295
Query 3641 MTWLELADTSLSGYRLKDCVMYASALVLLILMTAR------TVYDDAARRVWTLMNVITL 3694
+E +T+ ++ ++ +V+ ++ T R + + A ++ + N++ L
Sbjct 3296 QVLVENVNTTFLPVDMQGVMLALFCVVVFVICTIRFFTCKQSWFSLFATTIFVMFNIVKL 3355
Query 3695 VYKVYYGNALDQ----AISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
+ + D ++M ++IS+T+ VV +A IV ++ P
Sbjct 3356 LGMIGEPWTDDHFLLCLVNMLTMLISLTTKDWFVVFASYKVAYYIVVYVMQ--PAFVQDF 3413
Query 3751 NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKS 3810
++C+ ++Y GY CCY+G+ +NR+ +T GVY + VS E +YM + L PK+
Sbjct 3414 GFVKCVSIIYMACGYLFCCYYGILYWVNRFTCMTCGVYQFTVSPAELKYMTANNLSAPKT 3473
Query 3811 SIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3870
+ DA L+ KL+GIGG IK++TVQSK++++KCT+VVLL +L ++ VES+SK W CV
Sbjct 3474 AYDAMILSFKLMGIGGGRNIKISTVQSKLTEMKCTNVVLLGLLSKMHVESNSKEWNYCVG 3533
Query 3871 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPS 3930
LHN+I L D EK+++L++ LS D++ L E +N LQ++AS +++LPS
Sbjct 3534 LHNEINLCDDPDAVLEKLLALIAFFLSKHNTCDLSDLIESYFENTTILQSVASAYAALPS 3593
Query 3931 YAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 3990
+ AY A+ E+A N S +LK+L K+ N+AKSEF+R+A++Q+KL+KMA+QA MY
Sbjct 3594 WIAYEKARADLEEAKKNDVSPQLLKQLTKACNIAKSEFEREASVQKKLDKMAEQAAASMY 3653
Query 3991 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4050
K+AR+ D+++K+ SAM ++LF ML+KLD ++N II AR+G +PL+IIP +A +L+VV
Sbjct 3654 KEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIEQARNGVLPLSIIPAASATRLIVV 3713
Query 4051 VPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA 4110
P+ N YA A+W I +V DA+ V L E+ N N+ WPL +T R
Sbjct 3714 TPNLEVLSKVRQENNVHYAGAIWSIVEVKDANGAQVHLKEVTAANELNITWPLSITCERT 3773
Query 4111 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKW 4170
KLQNNE+ P L++ + A T + A + G F+ A ++ +LK+
Sbjct 3774 ---TKLQNNEILPGKLKEKAVKASATIDGDAYGSGKALMASEGGKSFIYAFIASDSNLKY 3830
Query 4171 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4230
++ ++ I ELE P RF D GP+VKYLYF+K LN L RG VLG + ATVRLQ
Sbjct 3831 VKWESNNDV--IPIELEAPLRFYVDGVNGPEVKYLYFVKSLNTLRRGAVLGYIGATVRLQ 3888
Query 4231 AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4290
AG TE P+NS +L+ CAFA DPAKAY D + G QP+TNCVKML G G AIT E
Sbjct 3889 AGKPTEHPSNSGLLTLCAFAPDPAKAYVDAVKRGMQPVTNCVKMLSNGAGNGMAITNGVE 3948
Query 4291 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 4350
+N Q+S+GGAS C+YCRCH++HP G C KGK+VQ+PT DP+ F + N VC VC
Sbjct 3949 SNTQQDSYGGASVCIYCRCHVEHPAIDGLCRFKGKFVQVPTG-TQDPIRFCIENEVCVVC 4007
Query 4351 GMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAA-RLTPCGTGTSTDVVYRAFDIYNE 4409
G W GC CD R + + ++LN CGV L PC GT D V RAFDIYN+
Sbjct 4008 GCWLTNGCMCD--RTSIQGTTIDQSYLNE-CGVLVQLDLEPC-NGTDPDHVSRAFDIYNK 4063
Query 4410 KVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHD 4469
VA KFLKTNC RF+ D+ D+Y+VVKR T S HE+ YN +KD VA HD
Sbjct 4064 DVACIGKFLKTNCSRFRNLDKH----DAYYVVKRCTKSVMDHEQVCYNDLKDSGVVAEHD 4119
Query 4470 FFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKK 4529
FF ++ +++R+ LTKYTM DL YA+R+FDE NC+ LKEILVT C++ +F K
Sbjct 4120 FFLYKEGRCEFGNVARKDLTKYTMMDLCYAIRNFDEKNCEVLKEILVTLGACNESFFENK 4179
Query 4530 DWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFG 4589
DW+D VEN I VYA LG V ++LK V FCDA+ + G +G++TLDNQDLNGN+YDFG
Sbjct 4180 DWFDPVENEAIHEVYARLGPIVANAMLKCVAFCDAIVEKGYIGIITLDNQDLNGNFYDFG 4239
Query 4590 DFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADL-AKPLIKWDLLKYDFTEER 4648
DFV+ PG G V SYYS +MP++ +T L +E+ + +D+ ++DLL YDFT+ +
Sbjct 4240 DFVKTTPGFGCACVTSYYSYMMPLMGMTSCLESENFVKSDIYGADYKQYDLLAYDFTDHK 4299
Query 4649 LCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVP 4708
LF +YFK+WD+TYHPNC +C D CI+HCANFN LFS P T+FGPLVRK+ +DGVP
Sbjct 4300 EKLFHKYFKHWDRTYHPNCSDCTSDECIIHCANFNTLFSMTIPSTAFGPLVRKVHIDGVP 4359
Query 4709 FVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVA 4768
VV+ GYHF++LG+V N DV L + +LS +LL + DP + AS LLD+RT CFS+A
Sbjct 4360 VVVTAGYHFKQLGIVWNLDVKLDTMKLSMTDLLRFVTDPTLLVASSPALLDQRTVCFSIA 4419
Query 4769 ALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYN 4828
AL+ V +QTVKPG+FNKDFYDF +GFF+EGS + LKHFFFAQ G AA++D++YYRYN
Sbjct 4420 ALSTGVTYQTVKPGHFNKDFYDFITERGFFEEGSELTLKHFFFAQGGEAAMTDFNYYRYN 4479
Query 4829 LPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSM 4888
T+ DI Q FV ++V KYF+CYDGGCINA +V+V N DKSAG+P NK+GKARLYY+++
Sbjct 4480 RVTVLDICQAQFVYKIVGKYFECYDGGCINAREVVVTNYDKSAGYPLNKFGKARLYYETL 4539
Query 4889 SYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSI 4948
SYE+QDALFA TKRNV+PT+TQMNLKYAIS K RARTV GVS+ STMT RQ+HQK LKSI
Sbjct 4540 SYEEQDALFALTKRNVLPTMTQMNLKYAISGKARARTVGGVSLLSTMTTRQYHQKHLKSI 4599
Query 4949 AATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLA 5008
AATR ATVVIG++KFYGGW NMLK + DV+ LMGWDYPKCDRA+PNM+R+ ++++L
Sbjct 4600 AATRNATVVIGSTKFYGGWDNMLKNLMRDVDNGCLMGWDYPKCDRALPNMIRMASAMILG 4659
Query 5009 RKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQA 5068
KH CC S RFYRL+NE AQVL+E+V C G Y KPGGT+SGD TTAYANS FNI QA
Sbjct 4660 SKHVGCCTHSDRFYRLSNELAQVLTEVVHCTGGFYFKPGGTTSGDGTTAYANSAFNIFQA 4719
Query 5069 VTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILS 5128
V+ANVN LL D N + V+++Q ++Y+ YR+ +D EFV E+++YLRKHFSMMILS
Sbjct 4720 VSANVNKLLGVDSNACNNVTVKSIQRKIYDNCYRSSSIDEEFVVEYFSYLRKHFSMMILS 4779
Query 5129 DDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTML 5188
DD VVCYN +YA G VA I FKA LYYQNNVFMS +KCW E DL+ GPHEFCSQHT+
Sbjct 4780 DDGVVCYNKDYADLGYVADINAFKATLYYQNNVFMSTSKCWVEPDLSVGPHEFCSQHTLQ 4839
Query 5189 VKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYAD 5248
+ D YLPYPDPSRIL AG FVDDIVKTD +M+ER+VSLAIDAYPLTKHP Y
Sbjct 4840 IVGPDGDYYLPYPDPSRILSAGVFVDDIVKTDNVIMLERYVSLAIDAYPLTKHPKPAYQK 4899
Query 5249 VFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVL 5308
VF+ L +++ L L +LD +SV + + ++W EFY ++Y TVLQA G CV+
Sbjct 4900 VFYTLLDWVKHLQKNLNAGVLDSFSVTMLEEGQDKFWSEEFYASLYEKSTVLQAAGMCVV 4959
Query 5309 CNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGG 5368
C SQT LRCG C+RRP LC KC YDHV+ T HK ++S+ PYVC+ GC+V DVT+L+LGG
Sbjct 4960 CGSQTVLRCGDCLRRPLLCTKCAYDHVMGTKHKFIMSITPYVCSFNGCNVNDVTKLFLGG 5019
Query 5369 MSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCT 5428
+SYYC HKP +SFPLCANG VFGLYK++ VGS++V DFN +A DWTN DY LAN
Sbjct 5020 LSYYCMDHKPQLSFPLCANGNVFGLYKSSAVGSEDVEDFNKLAVSDWTNVEDYKLANNVK 5079
Query 5429 ERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRV 5488
E LK+FAAET+KA EE+ K Y A ++EV+ +E+ L WE K +PPLNRN VFT +++
Sbjct 5080 ESLKIFAAETVKAKEESVKSEYAYAILKEVIGPKEIVLQWEASKTKPPLNRNSVFTCFQI 5139
Query 5489 TKNSKVQIGEYTFEKGDYG-DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHY 5547
+K++K+Q+GE+ FE+ +YG D+V Y+ T+TYKL G FVLTSH V PL A LV QE Y
Sbjct 5140 SKDTKIQLGEFVFEQSEYGSDSVYYKSTSTYKLTPGMIFVLTSHNVSPLKATILVNQEKY 5199
Query 5548 VRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVY 5607
I+ LYP NI++ +++ V YQ +G QK++T+QGPPG+GKSH IGL LYYP ARIVY
Sbjct 5200 NTISKLYPVFNIAEAYNTLVPYYQMIGKQKFTTIQGPPGSGKSHCVIGLGLYYPQARIVY 5259
Query 5608 TACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPET 5667
TACSHAAVDALCEKA K +D+CSRIIP R RV+C+ FK N+T QY+FCTVNALPE
Sbjct 5260 TACSHAAVDALCEKAAKNFNVDRCSRIIPQRIRVDCYTGFKPNNTNAQYLFCTVNALPEA 5319
Query 5668 TADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC 5727
+ DIVV DE+SM TNYDLSV+N+RL KH VY+GDP QLPAPRTL+ KG L+P+ +N V
Sbjct 5320 SCDIVVVDEVSMCTNYDLSVINSRLSYKHIVYVGDPQQLPAPRTLINKGVLQPQDYNVVT 5379
Query 5728 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSS 5787
+ + T+GPD+FL C RCPAEIV TVSALVY+NK +S QCFKMF KG + + +S
Sbjct 5380 QRVCTLGPDVFLHKCYRCPAEIVKTVSALVYENKFVPVNPESKQCFKMFVKGQVQIESNS 5439
Query 5788 AINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIF 5847
+IN Q+ VV+ FL NP WRKAVFISPYNSQN VA ++LGL TQTVDS+QGSEYDYVI+
Sbjct 5440 SINNKQLEVVKAFLAHNPKWRKAVFISPYNSQNYVARRLLGLQTQTVDSAQGSEYDYVIY 5499
Query 5848 TQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVT 5907
TQT++T H+ NVNRFNVAITRAK+GILCIM DR +Y+ L F L+ + LQA+ T
Sbjct 5500 TQTSDTQHATNVNRFNVAITRAKVGILCIMCDRTMYENLDFYELKDSK---IGLQAKPET 5556
Query 5908 -GLFKDCSKIITGLHPTQAPTHLSVDIKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMN 5965
GLFKDCSK + P A T++S+ FKT +GL V+I KD+ Y +IS MGF+
Sbjct 5557 CGLFKDCSKSEQYIPPAYATTYMSLSDNFKTSDGLAVNIG--TKDVKYANVISYMGFRFE 5614
Query 5966 YQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTG 6025
+ GY +F TR+ A+R+VRAW+GFDVEG H D VGTN+PLQLGFS GV+ V G
Sbjct 5615 ANIPGYHTLFCTRDFAMRNVRAWLGFDVEGAHVCGDNVGTNVPLQLGFSNGVDFVVQTEG 5674
Query 6026 YVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVF 6085
V TE V A+ PPG+QF HLIPLM KG PW++VR +IVQM+ D GLSD ++F
Sbjct 5675 CVVTEKGNSIEVVKARAPPGEQFAHLIPLMRKGQPWHIVRRRIVQMVCDYFDGLSDILIF 5734
Query 6086 VLWAHGFELTSMKYFVKIG-PERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMI 6144
VLWA G ELT+M+YFVKIG P++ C C K ATC+S+S YAC+ H++G DY+YNP+ I
Sbjct 5735 VLWAGGLELTTMRYFVKIGRPQK--CECGKSATCYSSSQCVYACFKHALGCDYLYNPYCI 5792
Query 6145 DVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDE 6204
D+QQWG+TG+L NH + C +H N HVAS DAIMTRCLA+H+CFVKRVDWS+ YP I +E
Sbjct 5793 DIQQWGYTGSLSMNHHEVCNIHRNEHVASGDAIMTRCLAIHDCFVKRVDWSIVYPFIDNE 5852
Query 6205 LRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYK 6264
++N A R VQ V+K+AL +HD+GNPK I+C + W YD P ++
Sbjct 5853 EKINKAGRIVQSHVMKAALKIFNPAAIHDVGNPKGIRCA-TTPIPWFCYDRDPINNNVRC 5911
Query 6265 IEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVN 6324
+E Y Y H +G+ LFWNCNVD YP +IVCRFDTR S L+L GC+GG+LYVN
Sbjct 5912 LE---YDYMVHGQ--MNGLMLFWNCNVDMYPEFSIVCRFDTRTRSKLSLEGCNGGALYVN 5966
Query 6325 KHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGA 6384
HAFHTPA+D+ AF LK +PFFYY DS CE V +YVPLKS CIT+CN+GGA
Sbjct 5967 NHAFHTPAYDRRAFAKLKPMPFFYYDDSNCE----LVDGQPNYVPLKSNVCITKCNIGGA 6022
Query 6385 VCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTR---LQSLENVAYNVVNK 6441
VC+ HA YR Y++ YNM + AGF++W + FDTY LW+ F LQSLENVA+NVV K
Sbjct 6023 VCKKHAALYRAYVEDYNMFMQAGFTIWCPQNFDTYMLWHGFVNSKALQSLENVAFNVVKK 6082
Query 6442 GHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKIL 6501
G F G G+ P ++I + + + D IF NKT+LP NVAFEL+AKR + P + IL
Sbjct 6083 GAFTGLKGDLPTAVIADKIMVRDGPTDKCIFTNKTSLPTNVAFELYAKRKLGLTPPLTIL 6142
Query 6502 NNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVD 6561
NLGV V+WDY+ E P T VC+ TD+ S + FD + G +
Sbjct 6143 RNLGVVATYKFVLWDYEAECPFSNFTKQVCSYTDLD--------SEVVTCFDNSIAGSFE 6194
Query 6562 LFRNARNGVLITEGSVKGLTPSKGPAQASVNG--VTLIGESVKTQFNYFKKVDGIIQQLP 6619
F ++ VLI+ +VKGL+ K +N V+ +G T + Y +K ++Q+
Sbjct 6195 RFTTTKDAVLISNNAVKGLSAIK-LQYGFLNDLPVSTVGNKPVTWYIYVRKNGEYVEQI- 6252
Query 6620 ETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHL 6679
++Y+T R E FKPRS ME DFL + FIQ+Y LE Y FEH+V+GD S +GG+HL
Sbjct 6253 DSYYTHGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEHVVFGDVSKTTIGGMHL 6312
Query 6680 MIGLAKRSQDSPLKLEDFIP-MDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQ 6738
+I + ++ +++F+ DST+K+ IT A SSK VC+ +D+LLDDFV IIKS
Sbjct 6313 LISQVRLAKMGLFSVQEFMTNSDSTLKSCCITYADDPSSKNVCTYMDILLDDFVTIIKSL 6372
Query 6739 DLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLE 6798
DL+V+SKVV V +D +MLWC++ ++TFYP+LQ+++ W PG +MP LYK+QRM LE
Sbjct 6373 DLNVVSKVVDVIVDCKAWRWMLWCENSQIKTFYPQLQSAE-WNPGYSMPTLYKIQRMCLE 6431
Query 6799 KCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTA 6858
+C+L NYG +P GI NV KYTQLCQYLNT T+ VP+ MRV+H GA GVAPG+
Sbjct 6432 RCNLYNYGAQVRLPDGITTNVVKYTQLCQYLNTTTVCVPHKMRVLHLGAAGASGVAPGST 6491
Query 6859 VLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKEN 6918
VLR+WLP +LVD+DL D+VSDAD ++ GDC +++ +K+DL+ISD+YD TK + EN
Sbjct 6492 VLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTSLYIEDKFDLLISDLYDGSTKSIDGEN 6551
Query 6919 DSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSE 6978
SK+GFFTY+ GFIK+KL+LGGS A+KITE SWN DLY+L+ F +WT F T+VN SSSE
Sbjct 6552 TSKDGFFTYINGFIKEKLSLGGSAAIKITEFSWNKDLYELIQRFEYWTVFCTSVNTSSSE 6611
Query 6979 AFLIGANYLGK--PKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMS 7036
FLIG NYLG K +DG MHANYIFWRN+ + LS S+ D KF + +++
Sbjct 6612 GFLIGINYLGPYCDKAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFKCRCNNALIVN 6671
Query 7037 LKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
LKE ++N+M+ LL KG+L+IR N +++ + LVN
Sbjct 6672 LKEKELNEMVVGLLRKGKLLIRNNGKLLNFGNHLVN 6707
Score = 60.1 bits (144), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 42/117 (36%), Positives = 58/117 (50%), Gaps = 1/117 (1%)
Query 1032 PMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKK 1091
P V+VNAAN L+H GGVA A++ T G + K S +Y+K + + G + L
Sbjct 1358 PDVLVNAANGDLRHVGGVARAIDVFTGGKLTKRSKEYLKSSKAIAPGNAVLFENVLEHLS 1417
Query 1092 CLHVVGPNLNAGEDIQLLKAAYENFNSQD-ILLAPLLSAGIFGAKPLQSLQVCVQTV 1147
L+ VGP L Y+ D +L PL+S GIF K SLQ ++TV
Sbjct 1418 VLNAVGPRNGDSRVEGKLCNVYKAIAKCDGKILTPLISVGIFKVKLEVSLQCLLKTV 1474
Score = 52.0 bits (123), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 71/285 (25%), Positives = 111/285 (39%), Gaps = 27/285 (9%)
Query 1544 TIKVFTTVDNTNLHTQLVDMSMTYGQQF-GPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
TI + T D N V + TYG+Q G + DVT P V+ G+
Sbjct 1499 TIPIKVTEDTVNQKRVSVALDKTYGEQLKGTVVIKDKDVTNQLPSVSDVGEKVV-----K 1553
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSI--KWADNNCYLSSVLLAL 1660
L + YY + + SA +H ++F V I K DNNC+++++ LAL
Sbjct 1554 ALDVDWNAYYGFPNAAAF----SASSH-DAYEFDVVTHNNFIVHKQTDNNCWVNAICLAL 1608
Query 1661 QQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLES 1720
Q+L+ + P ++ + A F ++ S T G+ GD T+ L+ + +S
Sbjct 1609 QRLKPTWKFPGVKSLWDAFLTRKTAGFVHMLYHISGLTKGQPGDAELTLHKLVDLMSSDS 1668
Query 1721 AKRVLN-VVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQES 1779
A V + C C K T TG + L G CV G +
Sbjct 1669 AVTVTHTTACDKCA-KVETFTGPVVAAPL-------LVCGTDEICVHGVHVNVKVTSIRG 1720
Query 1780 SFVMMS--APPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETL 1822
+ + S P + ++C YTG GHYT+ + L
Sbjct 1721 TVAITSLIGPVVGDVIDATGYIC---YTGLNSRGHYTYYDNRNGL 1762
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 4133 bits (10719), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2250/4966 (45%), Positives = 3051/4966 (61%), Gaps = 288/4966 (6%)
Query 2256 MDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFF 2315
+ +C G F C +CL DSL Y +++ YK + G+ W Y++F F
Sbjct 1801 LRYCAGDFTCRVCLHDRDSLHLYKHAYSVE---QIYKDAAS--GINFNWNWLYLVFLILF 1855
Query 2316 ---------------YLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRM 2360
YL+ S ++Q G+ L WF V +
Sbjct 1856 VKPVAGFVIICYCVKYLVLSSTVLQTGVGF----------LDWF---------VKTVFTH 1896
Query 2361 YIFFASFYYIWKSY-----VHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYA 2415
+ F + +Y W Y VH + C TC +C + R+ R E + +V G K+ +VY
Sbjct 1897 FNFMGAGFYFWLFYKIYVQVHHILYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYT 1956
Query 2416 NGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKN 2475
N G FCK HNW C NCD + +TF+S EVA +LS + KR + PT + ++V V +
Sbjct 1957 NSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKPTAYAYHVVYEACVVD 2016
Query 2476 GALHLYFDKA-GQKTYERHPLSHFVNLDNLR-ANNTKGSLPINVIVFDGKSKCDESAS-- 2531
++L + A K + F D L+ A K +L I DG C+ ++
Sbjct 2017 DFVNLKYKAAIPGKDNASSAVKCFSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSAHA 2076
Query 2532 ----KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLK 2587
K+A+VYY+Q +C+PIL+LDQAL + VS + D S SV
Sbjct 2077 LEEAKNAAVYYAQYLCKPILILDQALYEQL-IVEPVSKSVIDKVCSILSNIISVD----- 2130
Query 2588 ALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKD--VIECLKLSHHSDLEVTGD 2645
TA G D +LS TKD ++ H+ ++E TGD
Sbjct 2131 ----TAALNYKAGTLRDALLSI---------------TKDEEAVDMAIFCHNHEVEYTGD 2171
Query 2646 SCNNFMLTYN-KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRK 2704
N + +Y + +TPRD G I+ +A N +V + V +W D + LS+ K
Sbjct 2172 GFTNVIPSYGMDTDKLTPRDRGFLINADASIANLRVKNAPPV--VWKFSDLIKLSDSCLK 2229
Query 2705 QIRSAAKKNNIPFRLTCATTRQVVNVITTKISLK---GGKIVST------CFKLMLKATL 2755
+ SA K+ F +T + +QV++ T K+ ++ GG I +T CFK + +
Sbjct 2230 YLISATVKSGGRFFITKSGAKQVISCHTQKLLVEKKAGGVINNTFKWFMSCFKWLFVFYI 2289
Query 2756 LCVLAALVCYIVMPVHTLSIHDGY----TNEIIGYKAIQDGVTRDIISTDDCFANKHAGF 2811
L A + Y M ++ +H Y T + G+K I GV R+I+S D+CF+NK F
Sbjct 2290 L-FTACCLGYYYMEMNKSFVHPMYDVNSTLHVEGFKVIDKGVIREIVSEDNCFSNKFVNF 2348
Query 2812 DAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAING-DFLH---------F 2861
DA++ G SY+N+K+CP+V +I + G + G+PG V ++G F+H +
Sbjct 2349 DAFW---GKSYENNKNCPIVTVVIDGD-GTVAVGVPGFVSWVMDGVMFVHMTQTDRRPWY 2404
Query 2862 LPRVFS--AVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD-TNLLEG 2918
+P F+ VG YT +I F TS + +A C ++ A P YC++ N G
Sbjct 2405 IPTWFNREIVG---YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQLYCFNGDNDAPG 2460
Query 2919 SISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTS 2978
++ + + P Y +G + P L + +V YCR CE ++ G C+S
Sbjct 2461 ALPFGSIIPHRVYFQPNGVRLIVPQQILH-TPYIVKFVSDSYCRGSVCEYTKPGYCVSLD 2519
Query 2979 GRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAA 3038
+WVL N+ Y + GVFCG L+ N+ + V ++ + +I +++
Sbjct 2520 SQWVLFNDEYISKPGVFCGSTVRELMFNMVSTFFTGVNP-NIYIQLATMFLILVVIVLIF 2578
Query 3039 YYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVS 3098
+KF+ VF Y +V L+++++ +LC+ S L + V Y Y + + + +
Sbjct 2579 AMVIKFQGVFKAYATIVFTIMLVWVINAFVLCVHSYNSVLAVILLVLYCYASMVTSRNTA 2638
Query 3099 FLAHLQWFAMFSPIVPFWITAIYVFCISLKH---CHWFFNNYLRKRVMFNGVTF-STFEE 3154
+ H F IVP W+ Y+ I + W + R +++G F ++
Sbjct 2639 IIMHCWLVFTFGLIVPTWLACCYLGFILYMYTPLVFWCYGTTKNTRKLYDGNEFVGNYDL 2698
Query 3155 AALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKA 3214
AA TF++ ++KL +E ++ YL+ Y + KY+SG Y +A LA A
Sbjct 2699 AAKSTFVIRGTEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYA 2755
Query 3215 LNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD 3274
L+ + NSG +V+Y PP+ SI + LQ+GF+K+ PS VE C+V V+ LNGLWL D
Sbjct 2756 LDQYRNSGVEVVYTPPRYSIGVSRLQAGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGD 2815
Query 3275 TVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGN-VQLRVIGHSMQNCLLRLKVDT 3333
++YCPRHV+ + D+L +NH F V N V L V+ ++ +L L+
Sbjct 2816 SIYCPRHVL---GKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAV 2872
Query 3334 SNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNID 3393
+N +TPKYKFV+ G +F++ Y G+ G+Y MR N TI+ SFL G+CGSVGFNI+
Sbjct 2873 ANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIE 2932
Query 3394 YDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVI 3453
V+F YMHH+ELP +H GTDL G+FYG +VD + AQ D +T N++AWLYAA+I
Sbjct 2933 KGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAII 2992
Query 3454 N-------GDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA 3506
+ +W L T ++ D+N A + P + + LSA TG+ D+C
Sbjct 2993 SVKESSFSQPKW-LESTTVSIEDYNRWASDNGFTPFSTSTA--ITKLSAITGV---DVCK 3046
Query 3507 ALKELLQNGMNGRT--ILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHW----- 3559
L+ ++ + ILG EDE TP V Q GV Q F V+ W
Sbjct 3047 LLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQSSF---VRKATSWFWSRC 3103
Query 3560 MLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLP 3619
+L FL L +V T L F+V+ L +MA+ + VKH A++ FLLP
Sbjct 3104 VLACFLFVLCAIVLFTAVPLKFYVHAAVIL-----LMAVLFIS-FTVKHVMAYMDTFLLP 3157
Query 3620 SLATVA--------------------YFNMVYMPASWVMRIMTWLELADTSLSGYR-LKD 3658
+L TV + + Y P + ++ W+ L + ++ ++
Sbjct 3158 TLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVF-DTMVPWMLLPLVLYTAFKCVQG 3216
Query 3659 CVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVT 3718
C M + LL+L + ++T N +T + GN W L +
Sbjct 3217 CYMNSFNTSLLMLYQ----FMKLGFVIYTSSNTLTAYTE---GN--------WELFFELV 3261
Query 3719 SNYSGVVTTIMFLARAIVFVCVE----YYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLF 3774
+ L IVF C + Y + L +M+ +G+ C CYFGL+
Sbjct 3262 HTIVLANVSSNSLIGLIVFKCAKWMLYYCNATYFNNYVLMAVMV--NGIGWLCTCYFGLY 3319
Query 3775 CLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVAT 3834
+N+ F LTLG Y++ VS ++RYM + PPK+ + F NI + GIGG + +AT
Sbjct 3320 WWVNKVFGLTLGKYNFKVSVDQYRYMCLHKVNPPKTVWEVFTTNILIQGIGGDRVLPIAT 3379
Query 3835 VQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSV 3894
VQSK+SDVKCT+VVL+ +L +L VE++SK+ A V+LHN IL + D E + ++ +L
Sbjct 3380 VQSKLSDVKCTTVVLMQLLTKLNVEANSKMHAYLVELHNKILASDDVGECMDNLLGMLIT 3439
Query 3895 LLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVAN----GDS 3950
L + +D+ C+++L LQ++ EFS +PSYA Y A+ YE+ +A+ G +
Sbjct 3440 LFCIDSTIDLGEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKSIYEKVLADSKNGGVT 3499
Query 3951 EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTML 4010
+ L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+RAK+ S++ +L
Sbjct 3500 QQELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALL 3559
Query 4011 FTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYAS 4070
F+ML+K+D++ LN + + A G VPL +P+ + KL +V+PD T+ +G TY++
Sbjct 3560 FSMLKKIDSEKLNVLFDQANSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYST 3619
Query 4071 ALWEIQQVVDADSKIVQLSEINMD-----NSPNLAWPLIVTALRANSA---VKLQNNELS 4122
+W I V DAD + + + N+AWPL V R V LQNNEL
Sbjct 3620 VVWNIDCVTDADGTELHPTSTGSGLTYCISGDNIAWPLKVNLTRNGHNKVDVALQNNELM 3679
Query 4123 PVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTI 4182
P ++ +C AG Q C+ ++ YY + G V A+ S + +LK A F G I
Sbjct 3680 PHGVKTKACVAGVDQAHCSVESK-CYYTSISGSSVVAAITSSNPNLKVASFLNEAGN-QI 3737
Query 4183 YTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA-GNATEVPANS 4241
Y +L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+ G+ TE
Sbjct 3738 YVDLDPPCKFGMKVGDKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQSKGHETEEVDAV 3797
Query 4242 TVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGA 4301
+LS C+FAVDPA Y Y+A+G QP+ NCVKML H G+G AIT P DQ+S+GGA
Sbjct 3798 GILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSPTPDQDSYGGA 3857
Query 4302 SCCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYG 4357
S CLYCR HI HP N G C KG +VQIPTT DPVGF LRN VCTVC W GYG
Sbjct 3858 SVCLYCRAHIAHPGGAGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVCTVCQCWIGYG 3916
Query 4358 CSCDQLREP---LMQSADASTF----LNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEK 4410
C CD LR+P + A AS F LNRV G S ARL P G DVV RAFD+ N++
Sbjct 3917 CQCDSLRQPKPSVQSVAVASGFDKNYLNRVRGSSEARLIPLANGCDPDVVKRAFDVCNKE 3976
Query 4411 VAGFAKFLKTNCCRFQE--KDEEGNL--LDSYFVVKRHTMSNYQHEETIYNLVKDCPAVA 4466
AG + LK NC RFQE E+GNL DSYFVVK+ T SNY+HE+ Y +K A
Sbjct 3977 SAGMFQNLKRNCARFQEVRDTEDGNLEYCDSYFVVKQTTPSNYEHEKACYEDLKS-EVTA 4035
Query 4467 VHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDD--- 4523
HDFF F + + +ISRQRLTKYTM D YALRHFD +C+ LKEILVTY C +D
Sbjct 4036 DHDFFVFNKN---IYNISRQRLTKYTMMDFCYALRHFDPKDCEVLKEILVTYGCIEDYHP 4092
Query 4524 DYFNK-KDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLN 4582
+F + KDWYD +ENP + A +G VR++LL ++F + M + G VGV+TLDNQDLN
Sbjct 4093 KWFEENKDWYDPIENPKYYAMLAKMGPIVRRALLNAIEFGNLMVEKGYVGVITLDNQDLN 4152
Query 4583 GNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKY 4642
G +YDFGDF + APG GVP+ D+YYS +MPI+ +T ALA E + + D+ K +DLLKY
Sbjct 4153 GKFYDFGDFQKTAPGAGVPVFDTYYSYMMPIIAMTDALAPERYFEYDVHKGYKSYDLLKY 4212
Query 4643 DFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKI 4702
D+TEE+ LF +YFKYWDQ YHPNC +C DDRC++HCANFN+LFST+ P TSFG L RK+
Sbjct 4213 DYTEEKQDLFQKYFKYWDQEYHPNCRDCSDDRCLIHCANFNILFSTLVPQTSFGNLCRKV 4272
Query 4703 FVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRT 4762
FVDGVPF+ + GYH +ELGV+ NQD + S++ +L+ + DPA+ + N L+D RT
Sbjct 4273 FVDGVPFIATCGYHSKELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLVGTSNKLVDLRT 4332
Query 4763 TCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDY 4822
+CFSV AL + + QTVKPG+FNKDFYDFA G FKEGSS+ LKHFF+ Q GNAAI+DY
Sbjct 4333 SCFSVCALASGITHQTVKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFYPQTGNAAINDY 4392
Query 4823 DYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKAR 4882
DYYRYN PTM DIRQLLF +EV KYF+CY+GGCI A+QV+VNNLDKSAG+PFNK+GKAR
Sbjct 4393 DYYRYNRPTMFDIRQLLFCLEVTSKYFECYEGGCIPASQVVVNNLDKSAGYPFNKFGKAR 4452
Query 4883 LYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQ 4942
LYY+ MS E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI STMTNRQFHQ
Sbjct 4453 LYYE-MSLEEQDQLFESTKKNVLPTITQMNLKYAISAKNRARTVAGVSILSTMTNRQFHQ 4511
Query 4943 KLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIM 5002
K+LKSI TR A VVIGT+KFYGGW NML+ + VE P LMGWDYPKCDRAMPN+LRI
Sbjct 4512 KILKSIVNTRNAPVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKCDRAMPNLLRIA 4571
Query 5003 ASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSV 5062
ASLVLARKH CC S R YRL NECAQVLSE V+ G +YVKPGGTSSGDATTAYANSV
Sbjct 4572 ASLVLARKHTNCCTWSERVYRLYNECAQVLSETVLATGGIYVKPGGTSSGDATTAYANSV 4631
Query 5063 FNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHF 5122
FNI QA +ANV LLS I +++LQ+ LY+ +YR + D FV++FY+YL K+F
Sbjct 4632 FNIIQATSANVARLLSVITRDIVYDDIKSLQYELYQQVYRRVNFDPAFVEKFYSYLCKNF 4691
Query 5123 SMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFC 5182
S+MILSDD VVCYN+ A QGLVA I F+ VLYYQNNVFM+++KCW E DL KGPHEFC
Sbjct 4692 SLMILSDDGVVCYNNTLAKQGLVADISGFREVLYYQNNVFMADSKCWVEPDLEKGPHEFC 4751
Query 5183 SQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHP 5242
SQHTMLV+ + YLPYPDPSRIL A FVDD+ KT+ ++ER+++LAIDAYPL H
Sbjct 4752 SQHTMLVEVDGEPRYLPYPDPSRILCACVFVDDLDKTESVAVMERYIALAIDAYPLVHHE 4811
Query 5243 NQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQA 5302
N+EY VF + L YIRKL+ EL+ +ML YS ++ D S++WE EFYE MY T LQ+
Sbjct 4812 NEEYKKVFFVLLSYIRKLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYENMYRAPTTLQS 4871
Query 5303 VGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVT 5362
G CV+CNSQT LRCG CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C+ PGC DVT
Sbjct 4872 CGVCVVCNSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYICSQPGCGEADVT 4931
Query 5363 QLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYI 5422
+LYLGGMSY+C +HKP +S PL +NG VFG+Y+ C GS+NV DFN +AT +W+ YI
Sbjct 4932 KLYLGGMSYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLATTNWSTVEPYI 4991
Query 5423 LANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYV 5482
LAN C + L+ FAAET+KATEE K + A VREVLSDREL LSWE GK RPPLNRNYV
Sbjct 4992 LANRCVDSLRRFAAETVKATEELHKQQFASAEVREVLSDRELILSWEPGKTRPPLNRNYV 5051
Query 5483 FTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLV 5542
FTG+ T+ SKVQ+G++TFEKG+ D V YR T+T KL+VGD FVLTSH V+ L APTL
Sbjct 5052 FTGFHFTRTSKVQLGDFTFEKGEGKDVVYYRATSTAKLSVGDIFVLTSHNVVSLIAPTLC 5111
Query 5543 PQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPS 5602
PQ+ + R L P + + F +N+ Y VG QK +T+QGPPG+GKSHFAIGLA Y+ +
Sbjct 5112 PQQTFSRFVNLRPNVMVPACFVNNIPLYHLVGKQKRTTVQGPPGSGKSHFAIGLAAYFSN 5171
Query 5603 ARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVN 5662
AR+V+TACSHAAVDALCEKA K+L +D C+RI+P R ++CF KFK N T ++Y+F T+N
Sbjct 5172 ARVVFTACSHAAVDALCEKAFKFLKVDDCTRIVPQRTTIDCFSKFKANDTGKKYIFSTIN 5231
Query 5663 ALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEY 5722
ALPE + DI++ DE+SM TNY+LS +N ++ ++ VY+GDPAQLPAPRTLL G+L P+
Sbjct 5232 ALPEVSCDILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRTLLN-GSLSPKD 5290
Query 5723 FNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGV-- 5780
+N V LM + PD+FL C RCP EIVDTVS LVYD K A+ +S QCFK+
Sbjct 5291 YNVVTNLMVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRQCFKVIVNNGNS 5350
Query 5781 -ITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQG 5839
+ H+ SA N Q+ V++F+ RN WR+A FISPYN+ N A ++LGL QTVDSSQG
Sbjct 5351 DVGHESGSAYNITQLEFVKDFVCRNKEWREATFISPYNAMNQRAYRMLGLNVQTVDSSQG 5410
Query 5840 SEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRD-LYDKLQFTSLEIPRRNV 5898
SEYDYVIF T ++ H+ N+NRFNVA+TRAK GIL +M RD LY L+F L+ +V
Sbjct 5411 SEYDYVIFCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALKFIELD----SV 5466
Query 5899 ATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIP--KDMTYRRL 5956
A+LQ TGLFK C+K +G+HP A T ++ +K + + ++TY+ L
Sbjct 5467 ASLQG---TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNVEAGSEITYKHL 5523
Query 5957 ISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTG 6016
IS++GFKM+ V G NMFITR+EAIR+VR W+GFDVE HA +GTNLP Q+GFSTG
Sbjct 5524 ISLLGFKMSVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGTNLPFQVGFSTG 5583
Query 6017 VNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTL 6076
+ V P G VDT F VN+K PPG+QF HL L PW+VVR +IVQML+D L
Sbjct 5584 ADFVVTPEGLVDTSIGNNFEPVNSKAPPGEQFNHLRALFKSAKPWHVVRPRIVQMLADNL 5643
Query 6077 KGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFD 6136
+SD VVFV W HG ELT+++YFVKIG ++ C C RAT F++ + YACW H +GFD
Sbjct 5644 CNVSDCVVFVTWCHGLELTTLRYFVKIGKDQVCS-CGSRATTFNSHTQAYACWKHCLGFD 5702
Query 6137 YVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSV 6196
+VYNP ++D+QQWG++GNLQ NHD HC VHG+AHVAS DAIMTRCLA++ F + V+W +
Sbjct 5703 FVYNPLLVDIQQWGYSGNLQFNHDLHCNVHGHAHVASADAIMTRCLAINNAFCQDVNWDL 5762
Query 6197 EYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQ 6256
YP I +E VNS+CR +Q M + + + A K V++DIGNPK IKCV + ++ ++FYD
Sbjct 5763 TYPHIANEDEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRRGDLNFRFYDKN 5822
Query 6257 PCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGC 6316
P + E Y Y H DKF DG+C+FWNCNVD YP N++VCR+DTR LS NLPGC
Sbjct 5823 PIVPNVKQFE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDTRNLSVFNLPGC 5879
Query 6317 DGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCI 6376
+GGSLYVNKHAFHTP FD+++F NLK +PFF+Y SPCE+ V+ D V L + CI
Sbjct 5880 NGGSLYVNKHAFHTPKFDRTSFRNLKAMPFFFYDSSPCETIQLDGVAQ-DLVSLATKDCI 5938
Query 6377 TRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAY 6436
T+CN+GGAVC+ HA Y ++ +YN ++AGF+ W+ F+ YNLW +F+ LQS++N+AY
Sbjct 5939 TKCNIGGAVCKKHAQMYADFVTSYNAAVTAGFTFWVTNNFNPYNLWKSFSALQSIDNIAY 5998
Query 6437 NVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVP 6496
N+ GH+D AGE P + + V+ G++ +F N+T LP +VAFEL+AKRNI+ +P
Sbjct 5999 NMYKGGHYDAIAGEMPTIVTGDKVFVIDQGVEKAVFFNQTILPTSVAFELYAKRNIRTLP 6058
Query 6497 EIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRV 6556
+IL LGVD+ VIWDY + P + +T+ VC TDI + L VL+D R
Sbjct 6059 NNRILKGLGVDVTNGFVIWDYTNQTPLYRNTVKVCAYTDIEP-------NGLIVLYDDRY 6111
Query 6557 EGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASV-NGVTLIGESVKTQFNYFKKVDGII 6615
G F A N VL++ K + + P+ V NG+ L + +K+V+G
Sbjct 6112 -GDYQSFLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGIPLKDGA---NLYVYKRVNGAF 6167
Query 6616 QQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLG 6675
LP T TQ R E F+PRS +E DFL+++ + F+++Y E +HI+YG+ QLG
Sbjct 6168 VTLPNTLNTQGRSYETFEPRSDVERDFLDMSEESFVEKYGKE-LGLQHILYGEVDKPQLG 6226
Query 6676 GLHLMIGLAKRSQDSPLKLEDFIPMDSTV-KNYFITDAQTGSSKCVCSVIDLLLDDFV-- 6732
GLH +IG+ + + + L + DS V +NYF+ A GS K VC+V+DLLLDDF+
Sbjct 6227 GLHTVIGMCRLLRANKLNAKSVTNSDSDVMQNYFVL-ADNGSYKQVCTVVDLLLDDFLEL 6285
Query 6733 --EIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLY 6790
I+K + SKVV V+IDY I+FM W +DG ++T YP+LQ+ AW G MP LY
Sbjct 6286 LRNILKEYGTNK-SKVVTVSIDYHSINFMAWFEDGIIKTCYPQLQS--AWTCGYNMPELY 6342
Query 6791 KMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSD 6850
K+Q ++E C++ NYG +P GIMMNVAKYTQLCQYL+ T+ VP+NMRV+HFGAGSD
Sbjct 6343 KVQNCVMEPCNIPNYGVGIALPSGIMMNVAKYTQLCQYLSKTTMCVPHNMRVMHFGAGSD 6402
Query 6851 KGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY--- 6907
KGVAPG+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC T +K+DL+ISDMY
Sbjct 6403 KGVAPGSTVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYKTEHKFDLVISDMYTDN 6462
Query 6908 DPRTKHV-TKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWT 6966
D + KH N+ + F YL F++ LALGGS AVK+TE SW+ LY + +WWT
Sbjct 6463 DSKRKHEGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSWHEVLYDIAQDCAWWT 6522
Query 6967 AFVTNVNASSSEAFLIGANYLG-KPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKF 7025
F T VNASSSEAFL+G NYLG K ++ G T+HANYIFWRN N +Q S+YS+FD++KF
Sbjct 6523 MFCTAVNASSSEAFLVGVNYLGASEKVKVSGKTLHANYIFWRNCNYLQTSAYSIFDVAKF 6582
Query 7026 PLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILV 7071
L+L+ T V++LK Q D++++L++ G+L++R+ +SD V
Sbjct 6583 DLRLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6628
Score = 70.1 bits (170), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 51/198 (26%), Positives = 90/198 (45%), Gaps = 9/198 (5%)
Query 1591 EGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN 1650
E K +P+ D E Y+ LD Y+ L +KW ++W D N
Sbjct 1222 EDKEILFIPTTDKTILE----YYGLDAQKYVTYLQTL--AQKWDVQYRDNFVILEWRDGN 1275
Query 1651 CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMT 1710
C++SS ++ LQ +++F L EA+ + GD +F A A N VG+ D +
Sbjct 1276 CWISSAIVLLQAAKIRFKG-FLAEAWAKLLGGDPTDFVAWCYASCNAKVGDFSDANWLLA 1334
Query 1711 HLLQHANLESAKRVL-NVVCKHCGQKTTTLTGVEA-VMYMGTLSYDNLKTGVSIPCVCGR 1768
+L +H + + +L V +CG K+ L G+EA + + + + KT S CG
Sbjct 1335 NLAEHFDADYTNALLKKCVSCNCGVKSYELRGLEACIQPVRAPNLLHFKTQYSNCPTCGA 1394
Query 1769 DATQYLVQQESSFVMMSA 1786
+T +++ ++++ A
Sbjct 1395 SSTDEVIEASLPYLLLFA 1412
Score = 56.6 bits (135), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 88/355 (25%), Positives = 140/355 (39%), Gaps = 53/355 (15%)
Query 878 EAVVKTL-QPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDA 936
E VK L Q V D+L + G +D A L S + F + + A
Sbjct 870 EGAVKALPQKVIDVLGDWGEAVD----AQEQLCQQESTRVISEKSVEGFTGSCDAMAEQA 925
Query 937 ECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEE-------EEEDWLDDTTEQS 989
EE+EI E ++D P + ET +E +E+ + E+
Sbjct 926 IVEEQEIVPVVEQ---SQDVVVFTPADLEVVKETAEEVDEFILISAVPKEEVVSQEKEEP 982
Query 990 EIEPEPE------------------PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSAN 1031
++E EP T E+P +F Y ++A V I K
Sbjct 983 QVEQEPTLVVKAQREKKAKKFKVKPATCEKP--KFLEYKTCVGDLA---VVIAKALDEFK 1037
Query 1032 PMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKK 1091
IVNAAN H+ HGGGVA A+ + DY+K +GP + +
Sbjct 1038 EFCIVNAANEHMSHGGGVAKAIADFCGPDFVEYCADYVKKHGPQQ---KLVTPSFVKGIQ 1094
Query 1092 CL-HVVGPNLNAGEDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPLQSLQVCVQTVR 1148
C+ +VVGP + L AAY++ ++ + P+LS+GIFG ++ + +R
Sbjct 1095 CVNNVVGPRHGDSNLREKLVAAYKSVLVGGVVNYVVPVLSSGIFGV----DFKISIDAMR 1150
Query 1149 TQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVD 1203
+ + + L + +++D KQ+ TED + +SVV KP D
Sbjct 1151 -EAFKGCAIRVLLFSLSQEHIDYFDATC---KQKTIYLTEDG-VKYRSVVLKPGD 1200
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 4133 bits (10719), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2249/4959 (45%), Positives = 3052/4959 (62%), Gaps = 274/4959 (6%)
Query 2256 MDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFF 2315
+ +C F C +CL DSL Y +++ YK + G W Y++F F
Sbjct 1799 LRYCADDFICRVCLHDKDSLHLYKHAYSVE---QVYKDAAS--GFIFNWNWLYLVFLILF 1853
Query 2316 Y--LLGLSAIMQVFFGYFASHFISNS--------WLMWFIISIVQMAPVSAMVRMYIFFA 2365
+ G V Y + + NS +L WF V + + F
Sbjct 1854 VKPVAGF-----VIICYCVKYLVLNSTVLQTGVCFLDWF---------VQTVFSHFNFMG 1899
Query 2366 SFYYIWKSY-----VHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRG 2420
+ +Y W Y VH + C TC +C + R+ R E + +V G K+ +VY N G
Sbjct 1900 AGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYTNSGYN 1959
Query 2421 FCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHL 2480
FCK HNW C NCD + +TF+S EVA +LS + KR + PT + ++VD + + ++L
Sbjct 1960 FCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKPTAYAYHVVDEACLVDDFVNL 2019
Query 2481 YFDKAGQ-KTYERHPLSHFVNLDNLR-ANNTKGSLPINVIVFDGKSKCDESAS------K 2532
+ A K + F D L+ A K +L I DG C+ ++ K
Sbjct 2020 KYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSAHALEEAK 2079
Query 2533 SASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVAT 2592
+A++YY+Q +C+PIL+LDQAL + VS + D S+ SV T
Sbjct 2080 NAAIYYAQYLCKPILILDQALYEQLV-VEPVSKSVIDKVCSILSSIISVD---------T 2129
Query 2593 AHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKD--VIECLKLSHHSDLEVTGDSCNNF 2650
A G D +LS TKD ++ H+ D++ TGD N
Sbjct 2130 AALNYKAGTLRDALLSI---------------TKDEEAVDMAIFCHNHDVDYTGDGFTNV 2174
Query 2651 MLTYN-KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSA 2709
+ +Y +TPRD G I+ +A N +V + V +W + + LS+ K + SA
Sbjct 2175 IPSYGIDTGKLTPRDRGFLINADASIANLRVKNAPPV--VWKFSELIKLSDSCLKYLISA 2232
Query 2710 AKKNNIPFRLTCATTRQVVNVITTKISL--KGGKIVS---TCFKLMLKATLLCVLAALVC 2764
K+ + F +T + +QV+ T K+ + K G IVS CFK K L+ + C
Sbjct 2233 TVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKCFKSYFKWLLIFYILFTAC 2292
Query 2765 ---YIVMPVHTLSIHDGY----TNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQ 2817
Y M V +H Y T + G+K I GV R+I+ D CF+NK FDA++
Sbjct 2293 CSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVPEDTCFSNKFVNFDAFW-- 2350
Query 2818 RGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAING-DFLH---------FLPRVFS 2867
G Y N ++CP+V A+I + G + G+PG V ++G F+H ++P F+
Sbjct 2351 -GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMFIHMTQTERKPWYIPTWFN 2408
Query 2868 --AVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD-TNLLEGSISYSE 2924
VG YT +I F TS + +A C ++ A P YC++ N G++ +
Sbjct 2409 REIVG---YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALPFGS 2464
Query 2925 LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLN 2984
+ P Y +G + P L + VV YCR CE + G C+S + +WVL
Sbjct 2465 IIPHRVYFQPNGVRLIVPQQILH-TPYVVKFVSDSYCRGSVCEYTRPGYCVSLNPQWVLF 2523
Query 2985 NEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKF 3044
N+ Y + GVFCG L+ ++ + V ++ + +I ++V +KF
Sbjct 2524 NDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLATMFLILVVVVLIFAMVIKF 2582
Query 3045 RRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQ 3104
+ VF Y V L+++++ ILC+ S L + V Y Y + + + + H
Sbjct 2583 QGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLYCYASLVTSRNTVIIMHCW 2642
Query 3105 WFAMFSPIVPFWITAIYVFCISLKHCH---WFFNNYLRKRVMFNGVTF-STFEEAALCTF 3160
F IVP W+ Y+ I + W + R +++G F ++ AA TF
Sbjct 2643 LVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKLYDGNEFVGNYDLAAKSTF 2702
Query 3161 LLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSN 3220
++ ++KL +E ++ YL+ Y + KY+SG Y +A LA AL+ + N
Sbjct 2703 VIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQYRN 2759
Query 3221 SGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPR 3280
SG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+ LNGLWL DT+YCPR
Sbjct 2760 SGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIYCPR 2819
Query 3281 HVICTAEDMLNPNYEDLLIRKSNHSFLVQAGN-VQLRVIGHSMQNCLLRLKVDTSNPKTP 3339
HV+ + D+L +NH F V + V L V+ ++ +L L+ +N +TP
Sbjct 2820 HVL---GKFSGDQWNDVLNLANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANAETP 2876
Query 3340 KYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSF 3399
KYKF++ G +F++ Y G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F
Sbjct 2877 KYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNF 2936
Query 3400 CYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGD--- 3456
YMHH+ELP +H GTDL G+FYG +VD + AQ D +T N++AWLYAA+I+
Sbjct 2937 FYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESS 2996
Query 3457 ----RWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELL 3512
+W L T +++D+N A + P + + LSA TG+ D+C L+ ++
Sbjct 2997 FSLPKW-LESTTVSVDDYNKWAGDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIM 3050
Query 3513 --QNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHW-----MLLTFL 3565
+ G ILG EDE TP V Q GV Q F V+ W +L FL
Sbjct 3051 VKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSF---VRKATSWFWSRCVLACFL 3107
Query 3566 TSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVA 3625
L +V T L F+VY L +MA+ + VKH A++ FLLP+L TV
Sbjct 3108 FVLCAIVLFTAVPLKFYVYAAVIL-----LMAVLFIS-FTVKHVMAYMDTFLLPTLITVI 3161
Query 3626 --------------------YFNMVYMPASWVMRIMTWLELADTSLSGYR-LKDCVMYAS 3664
+ + Y P + ++ W+ L + ++ ++ C M +
Sbjct 3162 IGVCAEVPFIYNTLISQVVIFLSQWYDPVVF-DTMVPWMFLPLVLYTAFKCVQGCYMNSF 3220
Query 3665 ALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGV 3724
LL+L + ++T N +T + GN W L +
Sbjct 3221 NTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN--------WELFFELVHTTVLA 3265
Query 3725 VTTIMFLARAIVFVCVE---YYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYF 3781
+ L VF C + YY N + ++V C +G+ C CYFGL+ +N+ F
Sbjct 3266 NVSSNSLIGLFVFKCAKWMLYYCNATYLNNYVLMAVMVNC-IGWLCTCYFGLYWWVNKVF 3324
Query 3782 RLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSD 3841
LTLG Y++ VS ++RYM + PPK+ + F NI + GIGG + +ATVQ+K+SD
Sbjct 3325 GLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLPIATVQAKLSD 3384
Query 3842 VKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGA 3901
VKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E + ++ +L L +
Sbjct 3385 VKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGECMDNLLGMLITLFCIDST 3444
Query 3902 VDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVAN----GDSEVVLKKL 3957
+D++ C+++L LQ++ EFS +PSYA Y A+ YE+ + + G ++ L
Sbjct 3445 IDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAAY 3504
Query 3958 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4017
+K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K+
Sbjct 3505 RKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKI 3564
Query 4018 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQ 4077
D++ LN + + A G VPL +P+ + KL +V+PD T+ +G TY++ +W I
Sbjct 3565 DSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDT 3624
Query 4078 VVDADSKIVQLSEINMD-----NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQM 4129
V+DAD + + + N+AWPL V R V LQNNEL P ++
Sbjct 3625 VIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNKVDVVLQNNELMPHGVKTK 3684
Query 4130 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4189
+C AG Q C+ ++ YY N G V A+ S + +LK A F G IY +L+PP
Sbjct 3685 ACVAGVDQAHCSVESK-CYYTNISGNSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDPP 3742
Query 4190 CRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFCA 4248
C+F +V YLYFIK ++ RGMVLG+++ V LQ+ G+ TE +LS C+
Sbjct 3743 CKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLCS 3802
Query 4249 FAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCR 4308
FAVDPA Y Y+A+G QP+ NCVKML H G+G AIT P DQ+S+GGAS CLYCR
Sbjct 3803 FAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYCR 3862
Query 4309 CHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLR 4364
HI HP N G C KG +VQIPTT DPVGF LRN VCTVC W GYGC CD LR
Sbjct 3863 AHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSLR 3921
Query 4365 EP---LMQSADASTF----LNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKF 4417
+P + A AS F LNRV G S ARL P +G DVV RAFD+ N++ AG +
Sbjct 3922 QPKSSVQSVAGASDFDKNYLNRVRGSSEARLIPLASGCDPDVVKRAFDVCNKESAGMFQN 3981
Query 4418 LKTNCCRFQE--KDEEGNL--LDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKF 4473
LK NC RFQE E+GNL LDSYFVVK+ T SNY+HE++ Y +K A HDFF F
Sbjct 3982 LKRNCARFQELRDTEDGNLEYLDSYFVVKQTTPSNYEHEKSCYEDLKS-EVTADHDFFVF 4040
Query 4474 RVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDD---DYFNK-K 4529
+ + +ISRQRLTKYTM D YALRHFD +C+ LKEILVTY C +D +F + K
Sbjct 4041 NKN---IYNISRQRLTKYTMMDFCYALRHFDPKDCEVLKEILVTYGCIEDYHPKWFEENK 4097
Query 4530 DWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFG 4589
DWYD +EN + A +G VR++LL ++F + M + G VGV+TLDNQDLNG +YDFG
Sbjct 4098 DWYDPIENSKYYVMLAKMGPIVRRALLNAIEFGNLMVEKGYVGVITLDNQDLNGKFYDFG 4157
Query 4590 DFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERL 4649
DF + APG GVP+ D+YYS +MPI+ +T ALA E + + D+ K +DLLKYD+TEE+
Sbjct 4158 DFQKTAPGAGVPVFDTYYSYMMPIIAMTDALAPERYFEYDVHKGYKSYDLLKYDYTEEKQ 4217
Query 4650 CLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPF 4709
LF +YFKYWDQ YHPNC +C DDRC++HCANFN+LFST+ P TSFG L RK+FVDGVPF
Sbjct 4218 ELFQKYFKYWDQEYHPNCRDCSDDRCLIHCANFNILFSTLIPQTSFGNLCRKVFVDGVPF 4277
Query 4710 VVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAA 4769
+ + GYH +ELGV+ NQD + S++ +L+ + DPA+ + N L+D RT+CFSV A
Sbjct 4278 IATCGYHSKELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLVGTSNNLVDLRTSCFSVCA 4337
Query 4770 LTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNL 4829
LT+ + QTVKPG+FNKDFYDFA G FKEGSS+ LKHFF+ Q GNAAI+DYDYYRYN
Sbjct 4338 LTSGITHQTVKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFYPQTGNAAINDYDYYRYNR 4397
Query 4830 PTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMS 4889
PTM DI QLLF +EV KYF+CY+GGCI A+QV+VNNLDKSAG+PFNK+GKARLYY+ MS
Sbjct 4398 PTMFDICQLLFCLEVTSKYFECYEGGCIPASQVVVNNLDKSAGYPFNKFGKARLYYE-MS 4456
Query 4890 YEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIA 4949
E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI STMTNRQFHQK+LKSI
Sbjct 4457 LEEQDQLFEITKKNVLPTITQMNLKYAISAKNRARTVAGVSILSTMTNRQFHQKILKSIV 4516
Query 4950 ATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLAR 5009
TR A+VVIGT+KFYGGW NML+ + VE P LMGWDYPKCDRAMPN+LRI ASLVLAR
Sbjct 4517 NTRNASVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKCDRAMPNLLRIAASLVLAR 4576
Query 5010 KHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAV 5069
KH CC+ S R YRL NECAQVLSE V+ G +YVKPGGTSSGDATTAYANSVFNI QA
Sbjct 4577 KHTNCCSWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSSGDATTAYANSVFNIIQAT 4636
Query 5070 TANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSD 5129
+ANV LLS I +++LQ+ LY+ +YR + D FV++FY+YL K+FS+MILSD
Sbjct 4637 SANVARLLSVITRDIVYDNIKSLQYELYQQVYRRVNFDPAFVEKFYSYLCKNFSLMILSD 4696
Query 5130 DAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLV 5189
D VVCYN+ A QGLVA I F+ VLYYQNNVFM+++KCW E DL KGPHEFCSQHTMLV
Sbjct 4697 DGVVCYNNTLAKQGLVADISGFREVLYYQNNVFMADSKCWVEPDLEKGPHEFCSQHTMLV 4756
Query 5190 KQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADV 5249
+ + YLPYPDPSRILGA FVDD+ KT+ ++ER+++LAIDAYPL H N+EY V
Sbjct 4757 EVDGEPKYLPYPDPSRILGACVFVDDVDKTEPVAVMERYIALAIDAYPLVHHENEEYKKV 4816
Query 5250 FHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLC 5309
F + L YIRKL+ EL+ +ML YS ++ D S++WE EFYE MY T LQ+ G CV+C
Sbjct 4817 FFVLLAYIRKLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYENMYRAPTTLQSCGVCVVC 4876
Query 5310 NSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGM 5369
NSQT LRCG CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C+ GC DVT+LYLGGM
Sbjct 4877 NSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYICSQLGCGEADVTKLYLGGM 4936
Query 5370 SYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTE 5429
SY+C +HKP +S PL +NG VFG+Y+ C GS+NV DFN +AT +W+ YILAN C++
Sbjct 4937 SYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLATTNWSIVEPYILANRCSD 4996
Query 5430 RLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVT 5489
L+ FAAET+KATEE K + A VREV SDREL LSWE GK RPPLNRNYVFTGY T
Sbjct 4997 SLRRFAAETVKATEELHKQQFASAEVREVFSDRELILSWEPGKTRPPLNRNYVFTGYHFT 5056
Query 5490 KNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVR 5549
+ SKVQ+G++TFEKG+ D V Y+ T+T KL+VGD FVLTSH V+ L APTL PQ+ + R
Sbjct 5057 RTSKVQLGDFTFEKGEGKDVVYYKATSTAKLSVGDIFVLTSHNVVSLVAPTLCPQQTFSR 5116
Query 5550 ITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTA 5609
L P + + + F +N+ Y VG QK +T+QGPPG+GKSHFAIGLA+Y+ SAR+V+TA
Sbjct 5117 FVNLRPNVMVPECFVNNIPLYHLVGKQKRTTVQGPPGSGKSHFAIGLAVYFSSARVVFTA 5176
Query 5610 CSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTA 5669
CSHAAVDALCEKA K+L +D C+RI+P R V+CF KFK N T ++Y+F T+NALPE +
Sbjct 5177 CSHAAVDALCEKAFKFLKVDDCTRIVPQRTTVDCFSKFKANDTGKKYIFSTINALPEVSC 5236
Query 5670 DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRL 5729
DI++ DE+SM TNY+LS +N ++ ++ VY+GDPAQLPAPRTLL G+L P+ +N V L
Sbjct 5237 DILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRTLLN-GSLSPKDYNVVTNL 5295
Query 5730 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGV---ITHDVS 5786
M + PD+FL C RCP EIVDTVS LVYD K A+ +S +CFK+ + H+
Sbjct 5296 MVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRECFKVIVNNGNSDVGHESG 5355
Query 5787 SAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVI 5846
SA N Q+ V++F+ RN WR+A+FISPYN+ N A ++LGL QTVDSSQGSEYDYVI
Sbjct 5356 SAYNTTQLEFVKDFVCRNKQWREAIFISPYNAMNQRAYRMLGLNVQTVDSSQGSEYDYVI 5415
Query 5847 FTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRD-LYDKLQFTSLEIPRRNVATLQAEN 5905
F T ++ H+ N+NRFNVA+TRAK GIL +M RD LY L+FT L+ + +LQ
Sbjct 5416 FCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALKFTELD----SETSLQG-- 5469
Query 5906 VTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIP--KDMTYRRLISMMGFK 5963
TGLFK C+K +G+HP A T ++ +K + + ++TY+ LIS++GFK
Sbjct 5470 -TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNVEAGSEITYKHLISLLGFK 5528
Query 5964 MNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVP 6023
M+ V G NMFITR+EAIR+VR W+GFDVE HA +GTNLP Q+GFSTG + V P
Sbjct 5529 MSVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVTP 5588
Query 6024 TGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRV 6083
G VDT F VN+K PPG+QF HL L PW+V+R +IVQML+D L +SD V
Sbjct 5589 EGLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIRPRIVQMLADNLCNVSDCV 5648
Query 6084 VFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFM 6143
VFV W HG ELT+++YFVKIG E+ C C RAT F++ + YACW H +GFD+VYNP +
Sbjct 5649 VFVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPLL 5707
Query 6144 IDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGD 6203
+D+QQWG++GNLQ NHD HC VHG+AHVAS DAIMTRCLA++ F + V+W + YP I +
Sbjct 5708 VDIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAINNAFCQDVNWDLTYPHIAN 5767
Query 6204 ELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAY 6263
E VNS+CR +Q M + + + A K V++DIGNPK IKCV + +V ++FYD P
Sbjct 5768 EDEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRRGDVNFRFYDKNPIVRNVK 5827
Query 6264 KIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYV 6323
+ E Y Y H DKF DG+C+FWNCNVD YP N++VCR+DTR LS NLPGC+GGSLYV
Sbjct 5828 QFE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLYV 5884
Query 6324 NKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGG 6383
NKHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+ D V L + CIT+CN+GG
Sbjct 5885 NKHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ-DLVSLATKDCITKCNIGG 5943
Query 6384 AVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGH 6443
AVC+ HA Y +++ +YN ++AGF+ W+ + + YNLW +F+ LQS++N+AYN+ GH
Sbjct 5944 AVCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSFSALQSIDNIAYNMYKGGH 6003
Query 6444 FDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNN 6503
+D AGE P I + V+ G++ +F N+TTLP +VAFEL+AKRNI+ +P +IL
Sbjct 6004 YDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFELYAKRNIRTLPNNRILKG 6063
Query 6504 LGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLF 6563
LGVD+ VIWDY + P + +T+ VC TDI + L VL+D R G F
Sbjct 6064 LGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEP-------NGLVVLYDDRY-GDYQSF 6115
Query 6564 RNARNGVLITEGSVKGLTPSKGPAQASV-NGVTLIGESVKTQFNYFKKVDGIIQQLPETY 6622
A N VL++ K + + P+ V NG+ L + +K+V+G LP T
Sbjct 6116 LAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---NLYVYKRVNGAFVTLPNTI 6172
Query 6623 FTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIG 6682
TQ R E F+PRS +E DFL ++ + F++RY + +HI+YG+ QLGGLH +IG
Sbjct 6173 NTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHILYGEVDKPQLGGLHTVIG 6231
Query 6683 LAKRSQDSPLKLEDFIPMDSTV-KNYFITDAQTGSSKCVCSVIDLLLDDFV----EIIKS 6737
+ + + + L + DS V +NYF+ + GS K VC+V+DLLLDDF+ I+K
Sbjct 6232 MYRLLRANKLNAKSVTNSDSDVMQNYFVL-SDNGSYKQVCTVVDLLLDDFLELLRNILKE 6290
Query 6738 QDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLL 6797
+ SKVV V+IDY I+FM W +DG ++T YP+LQ+ AW G MP LYK+Q ++
Sbjct 6291 YGTNK-SKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQS--AWTCGYNMPELYKVQNCVM 6347
Query 6798 EKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGT 6857
E C++ NYG +P GI+MNVAKYTQLCQYL+ T+ VP+NMRV+HFGAGSDKGVAPG+
Sbjct 6348 EPCNIPNYGVGITLPSGILMNVAKYTQLCQYLSKTTICVPHNMRVMHFGAGSDKGVAPGS 6407
Query 6858 AVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY---DPRTKHV 6914
VL+QWLP GTLLVD+D+ D+VSDA +++ DC +T +K+DL+ISDMY D + KH
Sbjct 6408 TVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYNTEHKFDLVISDMYTDNDSKRKHE 6467
Query 6915 -TKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVN 6973
N+ + F YL F++ LALGGS AVK+TE SW+ LY + +WWT F T VN
Sbjct 6468 GVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSWHEVLYDIAQDCAWWTMFCTAVN 6527
Query 6974 ASSSEAFLIGANYLG-KPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGT 7032
ASSSEAFLIG NYLG K ++ G T+HANYIFWRN N +Q S+YS+FD++KF L+L+ T
Sbjct 6528 ASSSEAFLIGVNYLGASEKVKVSGKTLHANYIFWRNCNYLQTSAYSIFDVAKFDLRLKAT 6587
Query 7033 AVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILV 7071
V++LK Q D++++L++ G+L++R+ +SD V
Sbjct 6588 PVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6626
Score = 65.5 bits (158), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 57/220 (26%), Positives = 95/220 (43%), Gaps = 14/220 (6%)
Query 1570 QFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNH 1629
QFG Y V + E K +P+ D EYY LD Y+ L
Sbjct 1202 QFGQVYAKNKIVFTAD---DVEDKEILYVPTTD---KSILEYY-GLDAQKYVIYLQTL-- 1252
Query 1630 TKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCA 1689
+KW ++W D NC++SS ++ LQ +++F L EA+ + GD +F A
Sbjct 1253 AQKWNVQYRDNFLILEWRDGNCWISSAIVLLQAAKIRFKG-FLTEAWAKLLGGDPTDFVA 1311
Query 1690 LILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLN--VVCKHCGQKTTTLTGVEA-VM 1746
A VG+ D + +L +H + + L V C +CG K+ L G+EA +
Sbjct 1312 WCYASCTAKVGDFSDANWLLANLAEHFDADYTNAFLKKRVSC-NCGIKSYELRGLEACIQ 1370
Query 1747 YMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSA 1786
+ + + KT S CG + T +++ ++++ A
Sbjct 1371 PVRATNLLHFKTQYSNCPTCGANNTDEVIEASLPYLLLFA 1410
Score = 49.7 bits (117), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 15/186 (8%)
Query 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
V I K IVNAAN H+ HG GVA A+ + +DY+K +GP
Sbjct 1025 VVIAKALDEFKEFCIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ---R 1081
Query 1081 CLLSGHNLAKKCL-HVVGPNLNAGEDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPL 1137
+ +C+ +VVGP + L AAY+N ++ + P+LS GIFG
Sbjct 1082 LVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGV--- 1138
Query 1138 QSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSV 1197
++ + +R + + + L + +++D KQ+ TED + +S+
Sbjct 1139 -DFKMSIDAMR-EAFEGCTIRVLLFSLSQEHIDYFDVTC---KQKTIYLTEDG-VKYRSI 1192
Query 1198 VQKPVD 1203
V KP D
Sbjct 1193 VLKPGD 1198
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 4131 bits (10714), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 2249/4959 (45%), Positives = 3051/4959 (62%), Gaps = 274/4959 (6%)
Query 2256 MDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFF 2315
+ +C F C +CL DSL Y +++ YK + G W Y++F F
Sbjct 1799 LRYCADDFICRVCLHDKDSLHLYKHAYSVE---QVYKDAAS--GFIFNWNWLYLVFLILF 1853
Query 2316 Y--LLGLSAIMQVFFGYFASHFISNS--------WLMWFIISIVQMAPVSAMVRMYIFFA 2365
+ G V Y + + NS +L WF V + + F
Sbjct 1854 VKPVAGF-----VIICYCVKYLVLNSTVLQTGVCFLDWF---------VQTVFSHFNFMG 1899
Query 2366 SFYYIWKSY-----VHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRG 2420
+ +Y W Y VH + C TC +C + R+ R E + +V G K+ +VY N G
Sbjct 1900 AGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYTNSGYN 1959
Query 2421 FCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHL 2480
FCK HNW C NCD + +TF+S EVA +LS + KR + PT + ++VD + + ++L
Sbjct 1960 FCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKPTAYAYHVVDEACLVDDFVNL 2019
Query 2481 YFDKAGQ-KTYERHPLSHFVNLDNLR-ANNTKGSLPINVIVFDGKSKCDESAS------K 2532
+ A K + F D L+ A K +L I DG C+ ++ K
Sbjct 2020 KYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSAHALEEAK 2079
Query 2533 SASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVAT 2592
+A++YY+Q +C+PIL+LDQAL + VS + D S+ SV T
Sbjct 2080 NAAIYYAQYLCKPILILDQALYEQLV-VEPVSKSVIDKVCSILSSIISVD---------T 2129
Query 2593 AHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKD--VIECLKLSHHSDLEVTGDSCNNF 2650
A G D +LS TKD ++ H+ D++ TGD N
Sbjct 2130 AALNYKAGTLRDALLSI---------------TKDEEAVDMAIFCHNHDVDYTGDGFTNV 2174
Query 2651 MLTYN-KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSA 2709
+ +Y +TPRD G I+ +A N +V + V +W + + LS+ K + SA
Sbjct 2175 IPSYGIDTGKLTPRDRGFLINADASIANLRVKNAPPV--VWKFSELIKLSDSCLKYLISA 2232
Query 2710 AKKNNIPFRLTCATTRQVVNVITTKISL--KGGKIVS---TCFKLMLKATLLCVLAALVC 2764
K+ + F +T + +QV+ T K+ + K G IVS CFK K L+ + C
Sbjct 2233 TVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKCFKSYFKWLLIFYILFTAC 2292
Query 2765 ---YIVMPVHTLSIHDGY----TNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQ 2817
Y M V +H Y T + G+K I GV R+I+ D CF+NK FDA++
Sbjct 2293 CSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVPEDTCFSNKFVNFDAFW-- 2350
Query 2818 RGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAING-DFLH---------FLPRVFS 2867
G Y N ++CP+V A+I + G + G+PG V ++G F+H ++P F+
Sbjct 2351 -GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMFIHMTQTERKPWYIPTWFN 2408
Query 2868 --AVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD-TNLLEGSISYSE 2924
VG YT +I F TS + +A C ++ A P YC++ N G++ +
Sbjct 2409 REIVG---YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALPFGS 2464
Query 2925 LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLN 2984
+ P Y +G + P L + VV YCR CE + G C+S + +WVL
Sbjct 2465 IIPHRVYFQPNGVRLIVPQQILH-TPYVVKFVSDSYCRGSVCEYTRPGYCVSLNPQWVLF 2523
Query 2985 NEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKF 3044
N+ Y + GVFCG L+ ++ + V ++ + +I ++V +KF
Sbjct 2524 NDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLATMFLILVVVVLIFAMVIKF 2582
Query 3045 RRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQ 3104
+ VF Y V L+++++ ILC+ S L + V Y Y + + + + H
Sbjct 2583 QGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLYCYASLVTSRNTVIIMHCW 2642
Query 3105 WFAMFSPIVPFWITAIYVFCISLKHCH---WFFNNYLRKRVMFNGVTF-STFEEAALCTF 3160
F IVP W+ Y+ I + W + R +++G F ++ AA TF
Sbjct 2643 LVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKLYDGNEFVGNYDLAAKSTF 2702
Query 3161 LLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSN 3220
++ ++KL +E ++ YL+ Y + KY+SG Y +A LA AL+ + N
Sbjct 2703 VIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQYRN 2759
Query 3221 SGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPR 3280
SG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+ LNGLWL DT+YCPR
Sbjct 2760 SGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIYCPR 2819
Query 3281 HVICTAEDMLNPNYEDLLIRKSNHSFLVQAGN-VQLRVIGHSMQNCLLRLKVDTSNPKTP 3339
HV+ + D+L +NH F V + V L V+ ++ +L L+ +N +TP
Sbjct 2820 HVL---GKFSGDQWNDVLNLANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANAETP 2876
Query 3340 KYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSF 3399
KYKF++ G +F++ Y G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F
Sbjct 2877 KYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNF 2936
Query 3400 CYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGD--- 3456
YMHH+ELP +H GTDL G+FYG +VD + AQ D +T N++AWLYAA+I+
Sbjct 2937 FYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESS 2996
Query 3457 ----RWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELL 3512
+W L T +++D+N A + P + + LSA TG+ D+C L+ ++
Sbjct 2997 FSLPKW-LESTTVSVDDYNKWAGDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIM 3050
Query 3513 --QNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHW-----MLLTFL 3565
+ G ILG EDE TP V Q GV Q F V+ W +L FL
Sbjct 3051 VKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSF---VRKATSWFWSRCVLACFL 3107
Query 3566 TSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVA 3625
L +V T L F+VY L +MA+ + VKH A++ FLLP+L TV
Sbjct 3108 FVLCAIVLFTAVPLKFYVYAAVIL-----LMAVLFIS-FTVKHVMAYMDTFLLPTLITVI 3161
Query 3626 --------------------YFNMVYMPASWVMRIMTWLELADTSLSGYR-LKDCVMYAS 3664
+ + Y P + ++ W+ L + ++ ++ C M +
Sbjct 3162 IGVCAEVPFIYNTLISQVVIFLSQWYDPVVF-DTMVPWMFLPLVLYTAFKCVQGCYMNSF 3220
Query 3665 ALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGV 3724
LL+L + ++T N +T + GN W L +
Sbjct 3221 NTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN--------WELFFELVHTTVLA 3265
Query 3725 VTTIMFLARAIVFVCVE---YYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYF 3781
+ L VF C + YY N + ++V C +G+ C CYFGL+ +N+ F
Sbjct 3266 NVSSNSLIGLFVFKCAKWMLYYCNATYLNNYVLMAVMVNC-IGWLCTCYFGLYWWVNKVF 3324
Query 3782 RLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSD 3841
LTLG Y++ VS ++RYM + PPK+ + F NI + GIGG + +ATVQ+K+SD
Sbjct 3325 GLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLPIATVQAKLSD 3384
Query 3842 VKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGA 3901
VKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E + ++ +L L +
Sbjct 3385 VKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGECMDNLLGMLITLFCIDST 3444
Query 3902 VDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVAN----GDSEVVLKKL 3957
+D++ C+++L LQ++ EFS +PSYA Y A+ YE+ + + G ++ L
Sbjct 3445 IDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAAY 3504
Query 3958 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4017
+K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K+
Sbjct 3505 RKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKI 3564
Query 4018 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQ 4077
D++ LN + + A G VPL +P+ + KL +V+PD T+ +G TY++ +W I
Sbjct 3565 DSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDT 3624
Query 4078 VVDADSKIVQLSEINMD-----NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQM 4129
V+DAD + + + N+AWPL V R V LQNNEL P ++
Sbjct 3625 VIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNKVDVVLQNNELMPHGVKTK 3684
Query 4130 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4189
+C AG Q C+ ++ YY N G V A+ S + +LK A F G IY +L+PP
Sbjct 3685 ACVAGVDQAHCSVESK-CYYTNISGNSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDPP 3742
Query 4190 CRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFCA 4248
C+F +V YLYFIK ++ RGMVLG+++ V LQ+ G+ TE +LS C+
Sbjct 3743 CKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLCS 3802
Query 4249 FAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCR 4308
FAVDPA Y Y+A+G QP+ NCVKML H G+G AIT P DQ+S+GGAS CLYCR
Sbjct 3803 FAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYCR 3862
Query 4309 CHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLR 4364
HI HP N G C KG +VQIPTT DPVGF LRN VCTVC W GYGC CD LR
Sbjct 3863 AHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSLR 3921
Query 4365 EP---LMQSADASTF----LNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKF 4417
+P + A AS F LNRV G S ARL P +G DVV RAFD+ N++ AG +
Sbjct 3922 QPKSSVQSVAGASDFDKNYLNRVRGSSEARLIPLASGCDPDVVKRAFDVCNKESAGMFQN 3981
Query 4418 LKTNCCRFQE--KDEEGNL--LDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKF 4473
LK NC RFQE E+GNL LDSYFVVK+ T SNY+HE++ Y +K A HDFF F
Sbjct 3982 LKRNCARFQELRDTEDGNLEYLDSYFVVKQTTPSNYEHEKSCYEDLKS-EVTADHDFFVF 4040
Query 4474 RVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDD---DYFNK-K 4529
+ + +ISRQRLTKYTM D YALRHFD +C+ LKEILVTY C +D +F + K
Sbjct 4041 NKN---IYNISRQRLTKYTMMDFCYALRHFDPKDCEVLKEILVTYGCIEDYHPKWFEENK 4097
Query 4530 DWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFG 4589
DWYD +EN + A +G VR++LL ++F + M + G VGV+TLDNQDLNG +YDFG
Sbjct 4098 DWYDPIENSKYYVMLAKMGPIVRRALLNAIEFGNLMVEKGYVGVITLDNQDLNGKFYDFG 4157
Query 4590 DFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERL 4649
DF + APG GVP+ D+YYS +MPI+ +T ALA E + + D+ K +DLLKYD+TEE+
Sbjct 4158 DFQKTAPGAGVPVFDTYYSYMMPIIAMTDALAPERYFEYDVHKGYKSYDLLKYDYTEEKQ 4217
Query 4650 CLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPF 4709
LF +YFKYWDQ YHPNC +C DDRC++HCANFN+LFST+ P TSFG L RK+FVDGVPF
Sbjct 4218 ELFQKYFKYWDQEYHPNCRDCSDDRCLIHCANFNILFSTLIPQTSFGNLCRKVFVDGVPF 4277
Query 4710 VVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAA 4769
+ + GYH +ELGV+ NQD + S++ +L+ + DPA+ + N L+D RT+CFSV A
Sbjct 4278 IATCGYHSKELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLVGTSNNLVDLRTSCFSVCA 4337
Query 4770 LTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNL 4829
LT+ + QTVKPG+FNKDFYDFA G FKEGSS+ LKHFF+ Q GNAAI+DYDYYRYN
Sbjct 4338 LTSGITHQTVKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFYPQTGNAAINDYDYYRYNR 4397
Query 4830 PTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMS 4889
PTM DI QLLF +EV KYF+CY+GGCI A+QV+VNNLDKSAG+PFNK+GKARLYY+ MS
Sbjct 4398 PTMFDICQLLFCLEVTSKYFECYEGGCIPASQVVVNNLDKSAGYPFNKFGKARLYYE-MS 4456
Query 4890 YEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIA 4949
E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI STMTNRQFHQK+LKSI
Sbjct 4457 LEEQDQLFEITKKNVLPTITQMNLKYAISAKNRARTVAGVSILSTMTNRQFHQKILKSIV 4516
Query 4950 ATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLAR 5009
TR A+VVIGT+KFYGGW NML+ + VE P LMGWDYPKCDRAMPN+LRI ASLVLAR
Sbjct 4517 NTRNASVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKCDRAMPNLLRIAASLVLAR 4576
Query 5010 KHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAV 5069
KH CC+ S R YRL NECAQVLSE V+ G +YVKPGGTSSGDATTAYANSVFNI QA
Sbjct 4577 KHTNCCSWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSSGDATTAYANSVFNIIQAT 4636
Query 5070 TANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSD 5129
+ANV LLS I +++LQ+ LY+ +YR + D FV++FY+YL K+FS+MILSD
Sbjct 4637 SANVARLLSVITRDIVYDNIKSLQYELYQQVYRRVNFDPAFVEKFYSYLCKNFSLMILSD 4696
Query 5130 DAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLV 5189
D VVCYN+ A QGLVA I F+ VLYYQNNVFM+++KCW E DL KGPHEFCSQHTMLV
Sbjct 4697 DGVVCYNNTLAKQGLVADISGFREVLYYQNNVFMADSKCWVEPDLEKGPHEFCSQHTMLV 4756
Query 5190 KQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADV 5249
+ + YLPYPDPSRILGA FVDD+ KT+ ++ER+++LAIDAYPL H N+EY V
Sbjct 4757 EVDGEPKYLPYPDPSRILGACVFVDDVDKTEPVAVMERYIALAIDAYPLVHHENEEYKKV 4816
Query 5250 FHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLC 5309
F + L YIRKL+ EL+ +ML YS ++ D S++WE EFYE MY T LQ+ G CV+C
Sbjct 4817 FFVLLAYIRKLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYENMYRAPTTLQSCGVCVVC 4876
Query 5310 NSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGM 5369
NSQT LRCG CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C+ GC DVT+LYLGGM
Sbjct 4877 NSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYICSQLGCGEADVTKLYLGGM 4936
Query 5370 SYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTE 5429
SY+C +HKP +S PL +NG VFG+Y+ C GS+NV DFN +AT +W+ YILAN C++
Sbjct 4937 SYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLATTNWSIVEPYILANRCSD 4996
Query 5430 RLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVT 5489
L+ FAAET+KATEE K + A VREV SDREL LSWE GK RPPLNRNYVFTGY T
Sbjct 4997 SLRRFAAETVKATEELHKQQFASAEVREVFSDRELILSWEPGKTRPPLNRNYVFTGYHFT 5056
Query 5490 KNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVR 5549
+ SKVQ+G++TFEKG+ D V Y+ T+T KL+VGD FVLTSH V+ L APTL PQ+ + R
Sbjct 5057 RTSKVQLGDFTFEKGEGKDVVYYKATSTAKLSVGDIFVLTSHNVVSLVAPTLCPQQTFSR 5116
Query 5550 ITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTA 5609
L P + + + F +N+ Y VG QK +T+QGPPG+GKSHFAIGLA+Y+ SAR+V+TA
Sbjct 5117 FVNLRPNVMVPECFVNNIPLYHLVGKQKRTTVQGPPGSGKSHFAIGLAVYFSSARVVFTA 5176
Query 5610 CSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTA 5669
CSHAAVDALCEKA K+L +D C+RI+P R V+CF KFK N T ++Y+F T+NALPE +
Sbjct 5177 CSHAAVDALCEKAFKFLKVDDCTRIVPQRTTVDCFSKFKANDTGKKYIFSTINALPEVSC 5236
Query 5670 DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRL 5729
DI++ DE+SM TNY+LS +N ++ ++ VY+GDPAQLPAPRTLL G+L P+ +N V L
Sbjct 5237 DILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRTLLN-GSLSPKDYNVVTNL 5295
Query 5730 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGV---ITHDVS 5786
M + PD+FL C RCP EIVDTVS LVYD K A+ +S +CFK+ + H+
Sbjct 5296 MVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRECFKVIVNNGNSDVGHESG 5355
Query 5787 SAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVI 5846
SA N Q+ V++F+ RN WR+A+FISPYN+ N A ++LGL QTVDSSQGSEYDYVI
Sbjct 5356 SAYNTTQLEFVKDFVCRNKQWREAIFISPYNAMNQRAYRMLGLNVQTVDSSQGSEYDYVI 5415
Query 5847 FTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRD-LYDKLQFTSLEIPRRNVATLQAEN 5905
F T ++ H+ N+NRFNVA+TRAK GIL +M RD LY L+FT L+ + +LQ
Sbjct 5416 FCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALKFTELD----SETSLQG-- 5469
Query 5906 VTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIP--KDMTYRRLISMMGFK 5963
TGLFK C+K +G+HP A T ++ +K + + ++TY+ LIS++GFK
Sbjct 5470 -TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNVEAGSEITYKHLISLLGFK 5528
Query 5964 MNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVP 6023
M+ V G NMFITR+EAIR+VR W+GFDVE HA +GTNLP Q+GFSTG + V P
Sbjct 5529 MSVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVTP 5588
Query 6024 TGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRV 6083
G VDT F VN+K PPG+QF HL L PW+V+R +IVQML+D L +SD V
Sbjct 5589 EGLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIRPRIVQMLADNLCNVSDCV 5648
Query 6084 VFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFM 6143
VFV W HG ELT+++YFVKIG E+ C C RAT F++ + YACW H +GFD+VYNP +
Sbjct 5649 VFVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPLL 5707
Query 6144 IDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGD 6203
+D+QQWG++GNLQ NHD HC VHG+AHVAS DAIMTRCLA++ F + V+W + YP I +
Sbjct 5708 VDIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAINNAFCQDVNWDLTYPHIAN 5767
Query 6204 ELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAY 6263
E VNS+CR +Q M + + + A K V++DIGNPK IKCV + +V ++FYD P
Sbjct 5768 EDEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRRGDVNFRFYDKNPIVRNVK 5827
Query 6264 KIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYV 6323
+ E Y Y H DKF DG+C+FWNCNVD YP N++VCR+DTR LS NLPGC+GGSLYV
Sbjct 5828 QFE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLYV 5884
Query 6324 NKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGG 6383
NKHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+ D V L + CIT+CN+GG
Sbjct 5885 NKHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ-DLVSLATKDCITKCNIGG 5943
Query 6384 AVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGH 6443
AVC+ HA Y +++ +YN ++AGF+ W+ + + YNLW +F+ LQS++N+AYN+ GH
Sbjct 5944 AVCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSFSALQSIDNIAYNMYKGGH 6003
Query 6444 FDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNN 6503
+D AGE P I + V+ G++ +F N+TTLP +VAFEL+AKRNI+ +P +IL
Sbjct 6004 YDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFELYAKRNIRTLPNNRILKG 6063
Query 6504 LGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLF 6563
LGVD+ VIWDY + P + +T+ VC TDI + L VL+D R G F
Sbjct 6064 LGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEP-------NGLVVLYDDRY-GDYQSF 6115
Query 6564 RNARNGVLITEGSVKGLTPSKGPAQASV-NGVTLIGESVKTQFNYFKKVDGIIQQLPETY 6622
A N VL++ K + + P+ V NG+ L + +K+V+G LP T
Sbjct 6116 LAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---NLYVYKRVNGAFVTLPNTI 6172
Query 6623 FTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIG 6682
TQ R E F+PRS +E DFL ++ + F++RY + +HI+YG+ QLGGLH +IG
Sbjct 6173 NTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHILYGEVDKPQLGGLHTVIG 6231
Query 6683 LAKRSQDSPLKLEDFIPMDSTV-KNYFITDAQTGSSKCVCSVIDLLLDDFV----EIIKS 6737
+ + + + L + DS V +NYF+ + GS K VC+V+DLLLDDF+ I+K
Sbjct 6232 MYRLLRANKLNAKSVTNSDSDVMQNYFVL-SDNGSYKQVCTVVDLLLDDFLELLRNILKE 6290
Query 6738 QDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLL 6797
+ SKVV V+IDY I+FM W +DG ++T YP+LQ+ AW G MP LYK+Q ++
Sbjct 6291 YGTNK-SKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQS--AWTCGYNMPELYKVQNCVM 6347
Query 6798 EKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGT 6857
E C++ NYG +P GI+MNVAKYTQLCQYL T+ VP+NMRV+HFGAGSDKGVAPG+
Sbjct 6348 EPCNIPNYGVGITLPSGILMNVAKYTQLCQYLLKTTICVPHNMRVMHFGAGSDKGVAPGS 6407
Query 6858 AVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY---DPRTKHV 6914
VL+QWLP GTLLVD+D+ D+VSDA +++ DC +T +K+DL+ISDMY D + KH
Sbjct 6408 TVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYNTEHKFDLVISDMYTDNDSKRKHE 6467
Query 6915 -TKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVN 6973
N+ + F YL F++ LALGGS AVK+TE SW+ LY + +WWT F T VN
Sbjct 6468 GVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSWHEVLYDIAQDCAWWTMFCTAVN 6527
Query 6974 ASSSEAFLIGANYLG-KPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGT 7032
ASSSEAFLIG NYLG K ++ G T+HANYIFWRN N +Q S+YS+FD++KF L+L+ T
Sbjct 6528 ASSSEAFLIGVNYLGASEKVKVSGKTLHANYIFWRNCNYLQTSAYSIFDVAKFDLRLKAT 6587
Query 7033 AVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILV 7071
V++LK Q D++++L++ G+L++R+ +SD V
Sbjct 6588 PVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6626
Score = 65.1 bits (157), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 57/220 (26%), Positives = 95/220 (43%), Gaps = 14/220 (6%)
Query 1570 QFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNH 1629
QFG Y V + E K +P+ D EYY LD Y+ L
Sbjct 1202 QFGQVYAKNKIVFTAD---DVEDKEILYVPTTD---KSILEYY-GLDAQKYVIYLQTL-- 1252
Query 1630 TKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCA 1689
+KW ++W D NC++SS ++ LQ +++F L EA+ + GD +F A
Sbjct 1253 AQKWNVQYRDNFLILEWRDGNCWISSAIVLLQAAKIRFKG-FLTEAWAKLLGGDPTDFVA 1311
Query 1690 LILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLN--VVCKHCGQKTTTLTGVEA-VM 1746
A VG+ D + +L +H + + L V C +CG K+ L G+EA +
Sbjct 1312 WCYASCTAKVGDFSDANWLLANLAEHFDADYTNAFLKKRVSC-NCGIKSYELRGLEACIQ 1370
Query 1747 YMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSA 1786
+ + + KT S CG + T +++ ++++ A
Sbjct 1371 PVRATNLLHFKTQYSNCPTCGANNTDEVIEASLPYLLLFA 1410
Score = 49.7 bits (117), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 15/186 (8%)
Query 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
V I K IVNAAN H+ HG GVA A+ + +DY+K +GP
Sbjct 1025 VVIAKALDEFKEFCIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ---R 1081
Query 1081 CLLSGHNLAKKCL-HVVGPNLNAGEDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPL 1137
+ +C+ +VVGP + L AAY+N ++ + P+LS GIFG
Sbjct 1082 LVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGV--- 1138
Query 1138 QSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSV 1197
++ + +R + + + L + +++D KQ+ TED + +S+
Sbjct 1139 -DFKMSIDAMR-EAFEGCTIRVLLFSLSQEHIDYFDVTC---KQKTIYLTEDG-VKYRSI 1192
Query 1198 VQKPVD 1203
V KP D
Sbjct 1193 VLKPGD 1198
>sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus
HKU5 OX=694008 GN=1a PE=3 SV=1
Length=4481
Score = 2335 bits (6051), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1545/4568 (34%), Positives = 2378/4568 (52%), Gaps = 320/4568 (7%)
Query 13 HVQLSLPVLQVRDVLVR---GFGDSVEEALSEAREHLKNGTCGLV--ELEKGVLPQLEQP 67
HV L + D++++ F D E A E L G+ L + KG + L P
Sbjct 28 HVSLKASLCDAGDLVLKISPWFMDG-ESAYKHVSEQLSKGSKLLFVPQTLKGFIRHLPGP 86
Query 68 YVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITL-----GVLVPHVGETPIAYRNVL 122
V++ T +V +A + G G TL G+ P + L
Sbjct 87 RVYLVERLTGGTYSDPFMVNQLAYQNAAGEGVIGTTLQGKRVGMFFPFDADLVTGEFQFL 146
Query 123 LRKNGNKGAGGHSYGIDLKSY------DLGDELGTDPIEDYEQNWNTKHGSGALRELTRE 176
LRK KG GG+ + Y DL D L DP Y Q+ L ++
Sbjct 147 LRK---KGFGGNRFRDAPWDYNWTPYSDLMDALEADPCGKYSQS------------LLKK 191
Query 177 LNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAG--KSMCTLSEQLDYIESKRGVYCCRDH 234
L GG T +D CG +G P+ +A G K +E +S R + ++
Sbjct 192 LVGGDFTP-IDQYMCGKNGKPIAEFAALMASEGITKLADVEAEVKSRTDSDRYI-VFKNK 249
Query 235 EHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTE 294
+ I W +R D +Y Q+ F + S + DT + + P+ F + S+++VI P +
Sbjct 250 LYRIVWNVQRKDVAYSKQSAFTMNSIVQLDTME-DVPRHSFTIGSEIQVIAPSTAVQANG 308
Query 295 GFMGRIRSVYPVASPQ---ECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVI 351
+ R +Y Q E N ++ S + C C + SW T + ++ CG
Sbjct 309 HLNLKQRLLYAFYGKQAVSEPNYIYHSAYVDCTSCGKGSWLTGNAVQGFACDCGAHYCAN 368
Query 352 E-GPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRT--RCFGG 408
+ + G + NAV+ CP +D E +H++ + + + G+T +GG
Sbjct 369 DVDLQSSGLVRKNAVLLTTCPCNKDGEC--KHTLPQLVSMMTDKCDVEVVGKTFILTYGG 426
Query 409 CVFAYVGCYNKRAYWVPRASA-------DIGSGHTGITGDNVETLNEDLLEILSRERVNI 461
++AY+GC +++PRA + I +G TG ET N L R + I
Sbjct 427 VIYAYMGCSGGTMHFIPRAKSCVSKIGDAIFTGCTGTWSKVCETANL----FLERAQHAI 482
Query 462 NIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAW 521
N V +F L E V +L+ ++S D ++ ++ + + G + VT G ++G
Sbjct 483 NFVNEFVLTETVVALLSGTTSSIEELRDLCRNATFEKVRDYLTPRG-WIVTMGSYIEGVI 541
Query 522 NIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLV 581
N+G +C A ++ S + + L + LD ++ V
Sbjct 542 NVGA-----AGVCNAALNAPFIVLSGLGESFKKVAATPWKLCSSLRETLDHYADSITYRV 596
Query 582 -------DAMVYTSDLLTNSVII--MAYVTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIE 632
D YT+ LL +V+ AY V + + L+NL+ ++ + F ++
Sbjct 597 FPYDIPCDVTDYTALLLDCAVLTGASAYFVARYVDEKVEQLTNLVFSSCQSAVAAF--VQ 654
Query 633 AKLS---AGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMC 689
A +S A +F+ D + ++K + ++ V D +K F+ +++KA+++
Sbjct 655 ACMSTYKATAKFISDMFTLIKVVSERLYVYTSVGFVVVGDYSSQLLKQFMHILSKAMQLL 714
Query 690 IDQVTIAGAKLRSL--NLGEVFIAQSKGLYRQCIRGK---EQLQLLMPLK-APKEVTFLE 743
V+ AG+KL S+ N + + S Y +G+ +Q L++P + K++ LE
Sbjct 715 HTTVSWAGSKLPSVVYNGRDSLVFPSGTYYCVSTQGRSLQDQFDLVIPGDLSKKQIGILE 774
Query 744 GDSHDTVLTSE------EVVLKNGELEALETPVDSFTNGAIVGTPVCV-NGLMLLEIKDK 796
+ T + + EVV+ G+LE P + +VG V + N + + ++D
Sbjct 775 PTPNSTTVDKKINTNVVEVVV--GQLE----PTKEHSPELVVGDYVIISNKIFVRSVEDS 828
Query 797 EQ--YCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDERVDKVL 854
E Y + G + +FRLKGGAP KGV FG + E+ ++V + +++ +D +L
Sbjct 829 ETVFYPLCTDGKIVPT-LFRLKGGAPPKGVKFGGEQTKEITAVRSVSVDYDVHPVLDALL 887
Query 855 -NEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAG 913
+ + +TVE V +F VV + V++ L + G DL++++ Y+++ G
Sbjct 888 AGSELATFTVEKDLPVKDFVDVVKDEVIELLSKLLRGYNVDGFDLEDFADTPCYVYNAEG 947
Query 914 EENFSSRMYCSFYPPDEEEE--DDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETV 971
+ +SS M S P +E EE DD E+E + E E E+D + A+ E V
Sbjct 948 DLAWSSTMTFSVNPVEEVEEECDDDYVEDEYLSE----EMLVEEDEN----SWAAAVEAV 999
Query 972 RVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSAN 1031
E+ + D L + SE P + V + T+ V + +++ +Q AN
Sbjct 1000 IPMEDVQLDTLVAEIDVSE--------PADDVAEQAS----TEEVEVPSACVLEASQVAN 1047
Query 1032 PMVIVN-----AANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGH 1086
+ + +++I L A A + A ++ KL+ VG
Sbjct 1048 AAEVESCEAEVSSSIPLHEDANAAKANDCAEGMPALDSTETVSKLSVDTPVG-------- 1099
Query 1087 NLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQT 1146
V + + + + + +S+ ++ P + P ++L V+
Sbjct 1100 -------DVTQDDATSSNATVISEDVHTATHSKGLVAVPEVV-------PEKALGTSVER 1145
Query 1147 VRTQVYIAVNDKALYEQ--VVMDYLDNLKP-RVEAPKQEEPPNTEDSKTEEKSVVQKPVD 1203
+R+ V + +L ++ V++ + KP RV+ PK E P V D
Sbjct 1146 MRSTSEWTVVETSLKQETAVIVKNDSSAKPQRVKKPKAENPLKNFKHIVLNNDVTLVFGD 1205
Query 1204 VKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMV 1263
+A D + T I + S +++ E ++ P V
Sbjct 1206 AIAVARATEDCILVNAANTHLKHG-----GGIAAAIDRASGGLVQAESDDYVNFYGPLNV 1260
Query 1264 GDVIT------SGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEE 1317
GD + I VV P +A ++L R K ++Y AG E
Sbjct 1261 GDSTLLKGHGLATGILHVVGPDARANQDIQLLKRCYKAF--NKYPLVVSPLISAGIFCVE 1318
Query 1318 AKTALKKCKSA-----FYVLPSE-------APNAKEEI-LGTVSWNLREMLAHAEETRKL 1364
+ +L+ S + V+ SE AP + W R ++ +A+
Sbjct 1319 PRVSLEYLLSVVHTKTYVVVNSEKVYNDLAAPKPPTGLTYSHEGW--RGIIRNAKSFGFT 1376
Query 1365 MPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTM 1424
IC D A ++ + + + VD GV+++ Y+SK+P+ IIT N+ + + M
Sbjct 1377 CFICTDQSANAKLLKGRGVDLTKKTQTVD-GVKYYLYSSKDPLTDIITAANAC-KGICAM 1434
Query 1425 PIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLA 1484
PIGYVTHG +L +A + ++ + P V ++S D V N + + +T E+ F+ TV
Sbjct 1435 PIGYVTHGLDLAQAGQQVKKITVPYVCLLASKDQVPILNSDV--AVQTPEQSFINTVIAN 1492
Query 1485 GSYRDWSY-SGQRTELGVEF---LKRGDKIV------YHTLESPVEFHLDGEVLSLDKLK 1534
G Y W +G+ GV + L D+ + ++ ++ + D SL+K +
Sbjct 1493 GGYHCWHLVTGELIVKGVSYRKLLNWSDQTICYADNKFYVVKGQIALPFD----SLEKCR 1548
Query 1535 SLLSLR--EVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEG 1592
+ L+ R + K + V T+D N T +++ + TY Q G + G+D++ P G
Sbjct 1549 TYLTSRAAQQKNVDVLVTIDGVNFRTVVLNNTTTYRVQLGSVFYKGSDISDTIPTEKMSG 1608
Query 1593 KTFFVLPSDDTLRSEAF---EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADN 1649
+ ++ +D+ +E E Y T D +FL RY S L KKWK+ G+ S+K N
Sbjct 1609 EAVYL--ADNLSEAEKAVLSEVYGTADTAFLHRYYSLLALVKKWKYTVHDGVKSLKLNSN 1666
Query 1650 NCYLSSVLLALQQL-EVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRET 1708
NCY++ +L L L E+KF PALQ AY + + GD+ F ALI+AY + T GE D
Sbjct 1667 NCYVNVTMLMLDMLKEIKFIVPALQAAYLKHKGGDSTEFIALIMAYGDCTYGEPDDASRL 1726
Query 1709 MTHLLQHANLES-AKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCG 1767
+ +L A L + AK V C CG + TT TG++A +Y+G S D L C CG
Sbjct 1727 LHTILSKAELTTQAKMVWRQWCNVCGVQDTTTTGLKACIYVGMNSLDELHATHEECCQCG 1786
Query 1768 RDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTG-------NYQCGHYTHITAKE 1820
+ LV+ + ++++S + + +YT GHY H+ K+
Sbjct 1787 DVRKRQLVEHNAPWLLLSGLNEAKVMTPTSQSAGPDYTAFNVFQGVETSVGHYLHVRVKD 1846
Query 1821 TL-YRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKK 1879
L Y+ D L+K S+ K +TDV+Y + Y+ V Y LDG T+ +++P L +Y K
Sbjct 1847 NLLYKYDSGSLSKTSDMKCKMTDVYYPKQRYSADCNVVVYSLDGNTWADVDPDLSAFYMK 1906
Query 1880 DNAYYTEQP-IDLVPTQPLPNASFDNFKL-----TCSNTKFADDLNQMTGF--TKPASRE 1931
D Y+T++P I+ P L + + N L T + + N + GF +KP S++
Sbjct 1907 DGKYFTKKPVIEYSPATILSGSVYTNSCLVGHDGTIGSDAISSSFNNLLGFDNSKPVSKK 1966
Query 1932 LSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLW 1991
L+ +FFPD GDV+ +Y Y +K GA L KPI+W N K N LR ++
Sbjct 1967 LTYSFFPDFEGDVILTEYSTYDPIYKNGAMLHGKPILWVNNSKFDSALNKFNRATLRQVY 2026
Query 1992 STKPVDTSNSFEVLAVEDTQGMDNLAC-ESQQPTSE-EVVENPTIQKEVIECD-VKTTEV 2048
PV N + VL Q ++ A E +P S +V E+ + +I+C +K V
Sbjct 2027 DIAPVTLENKYTVLQDNQIQQVEVEAPKEDAKPQSPVQVAEDIDNKLPIIKCKGLKKPFV 2086
Query 2049 VGNVILKPSDEGVKVTQELGHEDLMAAYVE-NTSITIKKPNELSLALGLKTIATHG---I 2104
+GV V LG +DL A YV+ N + + K N S + T+ I
Sbjct 2087 KDGYSFVNDPQGVNVIDTLGIDDLRALYVDRNLRLIVLKENNWSALFNIHTVEKGDLSVI 2146
Query 2105 AAINSVPWS-KILAYVKPFLGQAAITTSNCAK-------RLAQRVFNN--YMPYVFTLLF 2154
AA S+ KIL Q A T N R+ + V N + F LL
Sbjct 2147 AASGSITRRVKILLGASSLFAQFASVTVNVTTAMGKALGRMTRNVITNTGIIGQGFALLK 2206
Query 2155 QLC----TFTKSTN-SRIRASLPTTIAKNSVKS-VAKLCLDAGINYVKSPKFSKLFTIAM 2208
L TF KS N S ++ + V + V K C A + V KF ++ +
Sbjct 2207 MLLILPFTFWKSKNQSTVKVEVGALRTAGIVTTNVVKQCASAAYD-VLVVKFKRIDWKST 2265
Query 2209 WLLLLSIC------------------LGSLICVTAAFGVLL------SNFGAPSYCNGVR 2244
LL IC L S + + A G+L S G S C+G+
Sbjct 2266 LRLLFLICTTGLLLSSLYYLFLFHQVLTSDVMLDGAEGMLATYRELRSYLGIHSLCDGMV 2325
Query 2245 ELYLNSSNVTTMDFCEG-SFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAE 2303
E Y N S DFC S C+ CL G DSL Y A + IQ ++SY +++ + E
Sbjct 2326 EAYRNVS-YDVNDFCSNRSALCNWCLIGQDSLTRYSAFQMIQTHVTSYVINIDWVWFVME 2384
Query 2304 WVLAYMLFTKFFYLLGLSAIMQVFFGYFAS--HFISNSWLMWFIISIVQMAPVSAMVRMY 2361
+ LAY+L+T F +L L Q FF Y + ++ S ++L+ V P+ +VR+Y
Sbjct 2385 FALAYVLYTSTFNVLLLVVSSQYFFSYTGAFVNWRSYNYLVSGYFFCVTHIPLLGLVRIY 2444
Query 2362 IFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGF 2421
F A +++ + Y H+++GC + C++CYKRNR TRVE +T+V G KR+FY+ ANGG F
Sbjct 2445 NFLACLWFLRRFYNHVINGCKDTACLLCYKRNRLTRVEASTVVCGSKRTFYIVANGGTSF 2504
Query 2422 CKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLY 2481
C HNWNC++CDT G+TFI +EVA DL+ +R + PTD+S Y V+SV VK+ + L+
Sbjct 2505 CCRHNWNCVDCDTAGIGNTFICEEVANDLTTSLRRLVKPTDKSHYYVESVTVKDSVVQLH 2564
Query 2482 FDKAGQKTYERHPLSHFVNLDNLRAN---NTKGSLPI-NVIVFDGKSKCDESASKSASVY 2537
+ + G YER+PL +F NLD L+ T +P N +++D + E+ ++SA VY
Sbjct 2565 YSREGASCYERYPLCYFTNLDKLKFKEVCKTPTGIPEHNFLIYDSSDRGQENLARSACVY 2624
Query 2538 YSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSEL 2597
YSQ++ +P+LL+D +V+ VGDS E++ KM D+YV++F + F V +KL LVATA +
Sbjct 2625 YSQVLSKPMLLVDSNMVTTVGDSREIASKMLDSYVNSFISLFGVNRDKLDKLVATARDCV 2684
Query 2598 AKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNK 2656
+G V+ TF AAR V++DV+T +++ L+ ++ DL++T + NN++ +Y K
Sbjct 2685 KRGDDFQTVIKTFTDAARGPAGVESDVETSSIVDALQYAYKHDLQLTTEGFNNYVPSYIK 2744
Query 2657 VENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIP 2716
+++ DLG ID NA +N ++ N + IWN DYM LS+ L++QIR A +K NIP
Sbjct 2745 PDSVATADLGCLIDLNAASVNQTSIRNANGACIWNSSDYMKLSDSLKRQIRIACRKCNIP 2804
Query 2717 FRLTCATTRQVVNVITTKIS---LKGG------KIVSTCFKLMLKATLLCVLAALVCYIV 2767
FRLT + R N+++ K S L GG K+ +K TL+ A++ Y+
Sbjct 2805 FRLTTSRLRSADNILSVKFSATKLSGGAPKWLLKLRDFTWKSYCVVTLVVFAMAVLSYLC 2864
Query 2768 MPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQR-GGSYKNDK 2826
+P +S + + I+ YK +++G+ RDI +D CFANK+ F WF++ GG + ND
Sbjct 2865 LPAFNMSQVSFHEDRILTYKVVENGIIRDITPSDTCFANKYQSFSKWFNEHYGGLFNNDI 2924
Query 2827 SCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFA 2886
SCPV A+I G VP LP V + + F+ RVF++ N+CYTP+ I Y F+
Sbjct 2925 SCPVTVAVIAGVAGARVPNLPANV-AWVGRQIVLFVSRVFASSNNVCYTPTAEIPYERFS 2983
Query 2887 TSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSI-IQFPNTY 2945
S CVLA+ECT+F+DA GK PYCYD +L G+ +Y +++P RY + D + I+FP
Sbjct 2984 DSGCVLASECTLFRDAEGKINPYCYDPTVLPGASAYDQMKPHVRYDMYDSDMYIKFPEVV 3043
Query 2946 LEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIA 3005
E ++R+ T YCR G+CE + G+C++T+G W + N+HY GV+CG + +++
Sbjct 3044 FESTLRITKTLATRYCRFGSCEDANEGVCITTNGSWAIYNDHYANKPGVYCGDNYFDIVR 3103
Query 3006 NIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMS 3065
+ L QPV +S S+ G ++ I +T A YY K +R +Y L++
Sbjct 3104 RLGLSLFQPVTYFQLSTSLALGVMLCIFLTIAFYYVNKVKRALADYTQCAVVAVAAALLN 3163
Query 3066 FTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCI 3125
LC V + L Y+ Y Y TFY T + +F+ H+ WF MF +VP W+ Y+ +
Sbjct 3164 SLCLCFVVSNPLLVLPYTALYYYATFYLTGEPAFVMHVSWFVMFGTVVPIWMVFAYIVGV 3223
Query 3126 SLKHCHWFFNNYLRK--RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ--Y 3181
L+H W + +K V +G +F++AA F++NK+ Y+ LR+ +TQ Y
Sbjct 3224 CLRHLLWVMAYFSKKHVEVFTDGKLNCSFQDAAANIFVINKDTYVALRNS----ITQDSY 3279
Query 3182 NRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQS 3241
NRYL+++NKYKY+SGA+DT SYREA+ HL KAL +S +G+DVL+QPP S+TS+VLQS
Sbjct 3280 NRYLSMFNKYKYYSGAMDTASYREASAAHLCKALQVYSETGSDVLFQPPNCSVTSSVLQS 3339
Query 3242 GFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRK 3301
G KMA PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C A+ + +PNY+ LL+ K
Sbjct 3340 GLVKMAAPSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDALLVSK 3399
Query 3302 SNHSFLVQ---AGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACY 3358
+N SF+VQ LRV+GH+M LL+L V+++NP+TP Y F ++PG +FSVLACY
Sbjct 3400 TNLSFIVQKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFSVLACY 3459
Query 3359 NGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLE 3418
NG P+GV+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H G +
Sbjct 3460 NGRPTGVFMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHTGCAFD 3519
Query 3419 GKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYN 3478
G YG F DRQ Q +D T+N++AWLYAA++NG WF+ T + FN AM
Sbjct 3520 GVMYGAFEDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEWAMSNQ 3579
Query 3479 Y-EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVV 3537
+ E + VD+L + +TG++V + A+ + L G G+TILG+++LEDEFTP DV
Sbjct 3580 FTEFIGTQSVDML---AHKTGVSVEQLLYAI-QTLHKGFQGKTILGNSMLEDEFTPDDVN 3635
Query 3538 RQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA 3597
Q GV Q K+I G HW+ T L + + +Q T+++++ +++E L T ++
Sbjct 3636 MQVMGVVMQSGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLTPLVLC 3695
Query 3598 IAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMP----ASWVMRIMTWLELADTSLSG 3653
+ AC ML VKHKH FL LFLLP+ + Y N+VY P +S ++ + WL A +
Sbjct 3696 VMACVMLTVKHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPASVYMRT 3755
Query 3654 YRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWAL 3713
D +Y S L ++ R +A+ L + + Y G+ ++
Sbjct 3756 TH-TDLGVYLSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPLTYLMF 3813
Query 3714 VISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGL 3773
+ ++TS+Y+ V + +A+ V Y P ++ ++L+Y +GY C YFG+
Sbjct 3814 LTTLTSDYTVTVFLAVNVAKFFARVVFLYAPHAGFIFPEVKLVLLMYLAVGYFCTVYFGV 3873
Query 3774 FCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVA 3833
F LLN R+ LGVYDY VSTQEFRY+ GL P++S +A +LN+KL+GIGG PCIK+A
Sbjct 3874 FSLLNLKLRVPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTPCIKIA 3933
Query 3834 TVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLS 3893
+VQSK++D+KCTSVVLLSVLQQL +E++SK WA CV+LHNDIL A D TEAF+ V L +
Sbjct 3934 SVQSKLTDLKCTSVVLLSVLQQLHLEANSKAWAHCVKLHNDILAATDPTEAFDNFVCLFA 3993
Query 3894 VLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEV 3952
L+S VD+ L ++LD+ + LQA SEFS L SYA AQ +Y++A+ +GD S
Sbjct 3994 TLMSFSANVDLEALASDLLDHPSVLQATLSEFSHLASYAELEAAQSSYQKALNSGDASPQ 4053
Query 3953 VLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFT 4012
VLK L+K++N+AK+ +++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF
Sbjct 4054 VLKALQKAVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFG 4113
Query 4013 MLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASAL 4072
M++KLDND LN +I+NAR+GCVPL+++PL + KL VV+PD + + +YA AL
Sbjct 4114 MIKKLDNDVLNGVISNARNGCVPLSVVPLCASNKLRVVIPDITIWNKVVTWPSLSYAGAL 4173
Query 4073 WEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALR-ANSAVKLQNNELSPVALRQMSC 4131
W+I + + D ++V+ S++ N +L WPL++ R A+SAV LQNNE+ P L+ M
Sbjct 4174 WDISLINNVDGEVVKSSDVTETNE-SLTWPLVLECTRAASSAVTLQNNEIRPSGLKTMVV 4232
Query 4132 AAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCR 4191
+AG C + ++LAYY +G + ++ +LS++ LKWA+ DG I EL+PPC+
Sbjct 4233 SAGIDHANC-NTSSLAYYEPVEGRKMLMGILSENAHLKWAKVEGRDGFVNI--ELQPPCK 4289
Query 4192 FVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAV 4251
F+ PKGP+V+YLYF+K LNNL+RG +LG +AATVRLQAG+ TE NS+VLS F+V
Sbjct 4290 FLIAGPKGPEVRYLYFVKNLNNLHRGQLLGHIAATVRLQAGSNTEFAINSSVLSAVTFSV 4349
Query 4252 DPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHI 4311
DP KAY D++ +GG P+TNCVKML TGTG A++V PEAN DQ+++GGAS CLYCR HI
Sbjct 4350 DPGKAYLDFVNAGGAPLTNCVKMLTPKTGTGIAVSVKPEANADQDTYGGASVCLYCRAHI 4409
Query 4312 DHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSA 4371
+HP+ G C KGK+VQ+P DPVGF L+NT C VC W G+GC+CD LR + +
Sbjct 4410 EHPDVTGVCKFKGKFVQVPLHI-RDPVGFCLQNTPCNVCQFWIGHGCNCDALRGTTIPQS 4468
Query 4372 DASTFLNR 4379
S FLN
Sbjct 4469 KDSNFLNE 4476
>sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus
HKU9 OX=694006 GN=1a PE=3 SV=1
Length=4248
Score = 2288 bits (5930), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1257/3111 (40%), Positives = 1831/3111 (59%), Gaps = 158/3111 (5%)
Query 1343 ILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDY-GVRFFFY 1401
++ VS + M+ +E L+P+ +D A + ++R +EG+ G F+ Y
Sbjct 1216 LVDVVSMSFSAMVNFGKEKGLLIPVVIDYPAFLKVLKR----FSPKEGLFSSNGYEFYGY 1271
Query 1402 TSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTT 1461
+ +P+ + LNSL PL+ +P G++ +G L +A MR L P V V S +V
Sbjct 1272 SRDKPLHEVSKDLNSLGRPLIMIPFGFIVNGQTLAVSAVSMRGLTVPHTVVVPSESSVPL 1331
Query 1462 YNGYLT---SSSKTSEEHFVETVSLAGSYRDWSYSGQRTELGVE------FLKRGDKIVY 1512
Y Y S T+ + FV + L G+ RDW +T V+ KRG+ Y
Sbjct 1332 YRAYFNGVFSGDTTAVQDFVVDILLNGA-RDWDV--LQTTCTVDRKVYKTICKRGN--TY 1386
Query 1513 HTLESPVEFHLDGEVL----SLDKLKSLLSLR---EVKTIKVFTTVDNTNLHTQLVDMSM 1565
+ + + G+V+ ++ K ++ L + IKV TTVD N T LV +
Sbjct 1387 LCFDDTNLYAITGDVVLKFATVSKARAYLETKLCAPEPLIKVLTTVDGINYSTVLVSTAQ 1446
Query 1566 TYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAF-EYYHTLDESFLGRYM 1624
+Y Q G + DG D + P EG + + + A EYY D + + R M
Sbjct 1447 SYRAQIGTVFCDGHDWSNKNPMPTDEGTHLYKQDNFSSAEVTAIREYYGVDDSNIIARAM 1506
Query 1625 SALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDA 1684
S + W + V G + D+NCYL+ + LQ ++V F+ P + AY + G+
Sbjct 1507 SIRKTVQTWPYTVVDGRVLLAQRDSNCYLNVAISLLQDIDVSFSTPWVCRAYDALKGGNP 1566
Query 1685 ANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEA 1744
+++A T G D ++ +L H + +A+RV+ VC+HCG TG +A
Sbjct 1567 LPMAEVLIALGKATPGVSDDAHMVLSAVLNHGTV-TARRVMQTVCEHCGVSQMVFTGTDA 1625
Query 1745 VMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQ-QGTFLCANE 1803
+ G++ D+L VS+ C CGR A +Y+ +Q+S +++MS P + L G + A
Sbjct 1626 CTFYGSVVLDDLYAPVSVVCQCGRPAIRYVSEQKSPWLLMSCTPTQVPLDTSGIWKTAIV 1685
Query 1804 YTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDG 1863
+ G GHY + + D + S+ K P TD+ Y TS+T+ K +Y LDG
Sbjct 1686 FRGPVTAGHYMYAVNGTLISVYDANTRRRTSDLKLPATDILYGPTSFTSDSKVETYYLDG 1745
Query 1864 VTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLT-CSNTKFADDLNQMT 1922
V T I+P Y K+ + Y+T PI++V P S+D F L+ C N + A+ N+
Sbjct 1746 VKRTTIDPDFSKYVKRGDYYFTTAPIEVV-AAPKLVTSYDGFYLSSCQNPQLAESFNKAI 1804
Query 1923 GFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKP 1982
TK +L +T +P++ GDVVAI + A G+ + KP+++ +P
Sbjct 1805 NATKTGPMKL-LTMYPNVAGDVVAISDDNVVAH-PYGSLHMGKPVLF---------VTRP 1853
Query 1983 NTWC-LRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIEC 2041
NTW L L ST V+T N+++VLAV+ P + E E P K I
Sbjct 1854 NTWKKLVPLLSTVVVNTPNTYDVLAVDPL------------PVNNETSEEPISVKAPIPL 1901
Query 2042 -DVKTTEVVGNVILKPSDEG-VKVTQELGHEDLMAAYVENTS-ITIKKPNELSLALGLKT 2098
+K T V+ P ++G + +E DL YVE + K + LS LGL+
Sbjct 1902 YGLKATMVLNGTTYVPGNKGHLLCLKEFTLTDLQTFYVEGVQPFVLLKASHLSKVLGLRV 1961
Query 2099 IATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTL-LFQLC 2157
+ +N + + AY A RL RV + + + T + +
Sbjct 1962 --SDSSLHVNHLSKGVVYAYA--------------ATRLTTRVTTSLLGGLVTRSVRKTA 2005
Query 2158 TFTKSTNS------------RIRASLPTTIAKNSVKSVAKL-CLDAG-------INYVKS 2197
F +STN ++ + K + V+ + + G +NY++S
Sbjct 2006 DFVRSTNPGSKCVGLLCLFYQLFMRFWLLVKKPPIVKVSGIIAYNTGCGVTTCVLNYLRS 2065
Query 2198 -------PKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELY--L 2248
+ KL +++ + CL IC GV LS APS + +
Sbjct 2066 RCGNISWSRLLKLLRYMLYIWFVWTCL--TIC-----GVWLSEPYAPSLVTRFKYFLGIV 2118
Query 2249 NSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAY 2308
+ ++ + +C++G+DSLD YPAL Q S + T + + E AY
Sbjct 2119 MPCDYVLVNETGTGWLHHLCMAGMDSLD-YPALRMQQHRYGS-PYNYTYILMLLEAFFAY 2176
Query 2309 MLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFY 2368
+L+T ++G+ A++ + Y + NSWL+ F+ I+++ P ++M+RMYI A +
Sbjct 2177 LLYTPALPIVGILAVLHLIVLYLPIP-LGNSWLVVFLYYIIRLVPFTSMLRMYIVIAFLW 2235
Query 2369 YIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWN 2428
+K ++H+ GC + C+MCYK+N A R+EC+T+VNG+KR FYV ANGG FC HNWN
Sbjct 2236 LCYKGFLHVRYGCNNVACLMCYKKNVAKRIECSTVVNGVKRMFYVNANGGTHFCTKHNWN 2295
Query 2429 CLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQK 2488
C++CDT+ STFI +VA DLS QFKRPI TD++ Y V SV V+NG ++ YF+ GQ+
Sbjct 2296 CVSCDTYTVDSTFICRQVALDLSAQFKRPIIHTDEAYYEVTSVEVRNGYVYCYFESDGQR 2355
Query 2489 TYERHPLSHFVNLDNLRANNTKGSLP-INVIVFDGKSKCDESASKSASVYYSQLMCQPIL 2547
+YER P+ F N+ L + KG+ P NV+VFD ++ +E+A K+A++YY+QL C+PIL
Sbjct 2356 SYERFPMDAFTNVSKLHYSELKGAAPAFNVLVFDATNRIEENAVKTAAIYYAQLACKPIL 2415
Query 2548 LLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVL 2607
L+D+ +V VGD ++ MF+AY + +S+ M+K+K L +TA +++ G+ ++ VL
Sbjct 2416 LVDKRMVGVVGDDATIARAMFEAYAQNYLLKYSIAMDKVKHLYSTALQQISSGMTVESVL 2475
Query 2608 STFVSAARQGVVD--TDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDL 2665
FV + R D +DVDT D++ C++L H E T DS NN + TY K + ++ ++
Sbjct 2476 KVFVGSTRAEAKDLESDVDTNDLVSCIRLCHQEGWEWTTDSWNNLVPTYIKQDTLSTLEV 2535
Query 2666 GACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTR 2725
G + NA+++NA +AK V+LIW D++ LSE +R+Q++ AA+K + +T ++ +
Sbjct 2536 GQFMTANAKYVNANIAKGAAVNLIWRYADFIKLSESMRRQLKVAARKTGLNLLVTTSSLK 2595
Query 2726 QVVNVITTKISLKGG--KIVSTCFKLMLKATLLCVLAA---LVCYIVMPVHTLSIHDGYT 2780
V + T + GG +IVS L+ LL VL YI+ P+
Sbjct 2596 ADVPCMVTPFKIIGGHRRIVSWRRVLIHVFMLLVVLNPQWFTPWYIMRPIEY-------- 2647
Query 2781 NEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIG 2840
++ +K I + V RDI S D CFANK + F+ W+S R GSY N + CP+V +++ +G
Sbjct 2648 -NVVDFKVIDNAVIRDITSADQCFANKFSAFENWYSNRYGSYVNSRGCPMVVGVVSDIVG 2706
Query 2841 FIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFK 2900
+VPGLP LR + L + AVG++CYTP I Y F TSACVLAA CT+F
Sbjct 2707 SLVPGLPARFLR-VGTTLLPLVNYGLGAVGSVCYTPHYAINYDVFDTSACVLAATCTLFS 2765
Query 2901 DAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAE 2959
A G+ +PYC D L++ + Y L+P Y + S I+FP + V +V T E
Sbjct 2766 SASGERMPYCADAALIQNASRYDMLKPHVMYPFYEHSGYIRFPEV-ISAGVHIVRTMAME 2824
Query 2960 YCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALD 3019
YC+ G C+ SE G+C+S RWV+NN ++R SGV+CG A +L N+ P+ PVGA+D
Sbjct 2825 YCKVGRCDVSEAGLCMSLQPRWVVNNAYFRQQSGVYCGTSAFDLFMNMLLPIFTPVGAVD 2884
Query 3020 VSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLP 3079
++ S++ G ++A++V+ + YY ++FRR FG+Y+ V+ N L F+++ +LCL Y LP
Sbjct 2885 ITTSILMGALLAVVVSMSLYYLLRFRRAFGDYSGVIFTNILAFVLNVIVLCLEGPYPMLP 2944
Query 3080 GVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLR 3139
+Y++ +LY T YF +D++ + H+ + MF+ +VP W+T +Y+ + +H WF + +
Sbjct 2945 SIYAMVFLYATCYFGSDIACMMHVSFLIMFAGVVPLWVTVLYIVVVLSRHILWFASLCTK 3004
Query 3140 KRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALD 3199
+ V + F +F++AAL TF+L+KE++L+L+ E + Y +YLA+YNKYKY+SG +D
Sbjct 3005 RTVQVGDLAFHSFQDAALQTFMLDKEVFLRLKRE--ISSDAYFKYLAMYNKYKYYSGPMD 3062
Query 3200 TTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQ 3259
T +YREAAC HL AL +SN G D +YQPP+ S+ SA LQ+G +MA PSG VE C+V+
Sbjct 3063 TAAYREAACSHLVMALEKYSNGGGDTIYQPPRCSVASAALQAGLTRMAHPSGLVEPCLVK 3122
Query 3260 VTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIG 3319
V G+ TLNG+WLD+ V CPRHV+C+ +++ NP+Y L +R +N+ F V +RVIG
Sbjct 3123 VNYGSMTLNGIWLDNFVICPRHVMCSRDELANPDYPRLSMRAANYDFHVSQNGHNIRVIG 3182
Query 3320 HSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGS 3379
H+M+ LL+L VD +NPKTP Y F+R+ GQ S+LACY+G P+GVY C +R N T++ S
Sbjct 3183 HTMEGSLLKLTVDVNNPKTPAYSFIRVSTGQAMSLLACYDGLPTGVYTCTLRSNGTMRAS 3242
Query 3380 FLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTT 3439
FL GSCGS GF ++ V FCY+H +ELP G H GTD G FYGPF D+Q Q A D T
Sbjct 3243 FLCGSCGSPGFVMNGKEVQFCYLHQLELPNGTHTGTDFSGVFYGPFEDKQVPQLAAPDCT 3302
Query 3440 ITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGI 3499
IT+NVLAWLYAAV++G+ WFL + + + +FN A+KY + +T + + +L PL+A+TGI
Sbjct 3303 ITVNVLAWLYAAVLSGENWFLTKSSISPAEFNNCAVKYMCQSVTSESLQVLQPLAAKTGI 3362
Query 3500 AVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHW 3559
+V M +ALK LL G GRTI+GS LEDE TP+D+ RQ GV QGKF+ + + T W
Sbjct 3363 SVERMLSALKVLLSAGFCGRTIMGSCSLEDEHTPYDIGRQMLGVKLQGKFQSMFRWTLQW 3422
Query 3560 MLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAM------LLVKHKHAFL 3613
+ F+ ++LIL+Q QW+ LPFTL + I A+ LL+KHKH +L
Sbjct 3423 FAIIFVLTILILLQLAQWTFV------GALPFTLLLPLIGFVAVCVGFVSLLIKHKHTYL 3476
Query 3614 CLFLLPSLATVAYFNMVYMP---ASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLI 3670
++LLP AY+N Y P +++ + ++ + G L ++ + A LL
Sbjct 3477 TVYLLPVAMVTAYYNFQYTPEGVQGYLLSLYNYVNPGRIDVIGTDLLTMLIISVACTLL- 3535
Query 3671 LMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMF 3730
+ R V DA R+W + + +Y + G+A AIS ++SV +NY+GV ++
Sbjct 3536 --SVRMVRTDAYSRIWYVCTAVGWLYNCWTGSADTVAISYLTFMVSVFTNYTGVACASLY 3593
Query 3731 LARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDY 3790
A+ +V+V P + + +C+++ Y +GY C CYFG+F L+NR FR TLG Y+Y
Sbjct 3594 AAQFMVWVLKFLDPTILLLYGRFRCVLVCYLLVGYLCTCYFGVFNLINRLFRCTLGNYEY 3653
Query 3791 LVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLL 3850
+VS+QE RYMNS GLLPP +S A LNIKL GIGG P +V+T+QS M+D+KCTSVVLL
Sbjct 3654 VVSSQELRYMNSHGLLPPTNSWQALMLNIKLAGIGGIPIYRVSTIQSNMTDLKCTSVVLL 3713
Query 3851 SVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEE 3910
SVLQQLRVESSSKLWA CV+LHN+IL + TEAFE VSLLSVLLS+ GA++++ LC
Sbjct 3714 SVLQQLRVESSSKLWALCVKLHNEILASNSPTEAFEAFVSLLSVLLSLPGAINLDELCSS 3773
Query 3911 MLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR 3970
+L+N + LQA+ASEFS+L SY Y AQ+AY+ AVA G + LKK++NVAKS D+
Sbjct 3774 ILENNSVLQAVASEFSNLSSYVDYENAQKAYDTAVATGAPASTVNALKKAMNVAKSVLDK 3833
Query 3971 DAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNAR 4030
D A RKLE+M++ AMT MYKQAR+ED+R+KVT+AMQTMLF M+R+LD+DAL+NI+NNAR
Sbjct 3834 DVATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQTMLFNMIRRLDSDALSNILNNAR 3893
Query 4031 DGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSE 4090
+G VPL +IP T A KL++VVPD+ Y T T TYA + W++ QV DAD K V ++
Sbjct 3894 NGVVPLGVIPRTAANKLLLVVPDFSVYTATITMPTLTYAGSAWDVMQVADADGKTVNATD 3953
Query 4091 INMDNSPNLAWPLIVTALR--ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAY 4148
I +NS NLAWPL+VTA R A S VKLQNNEL P +++M+ AG +QTAC D A+AY
Sbjct 3954 ITRENSVNLAWPLVVTAQRQQATSPVKLQNNELMPQTVKRMNVVAGVSQTACVTD-AVAY 4012
Query 4149 YNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFI 4208
YN +K GR V+A+L+D L +A+ KS G G + ELEPPC+F+ DTPKGP +KYLYF
Sbjct 4013 YNATKEGRHVMAILADTDGLAFAKVEKSTGDGFVILELEPPCKFMVDTPKGPALKYLYFT 4072
Query 4209 KGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPI 4268
KGL NL RG VLG+LA TVRL AG+ATEV +NS++LS C+F+VDP YKDYL +GG PI
Sbjct 4073 KGLKNLCRGTVLGTLACTVRLHAGSATEVASNSSILSLCSFSVDPEATYKDYLDNGGSPI 4132
Query 4269 TNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQ 4328
NCVKML HTGTG AIT P+AN+DQESFGGASCCLYCRCHI+HP G C KGK+VQ
Sbjct 4133 GNCVKMLTPHTGTGLAITAKPDANIDQESFGGASCCLYCRCHIEHPGASGVCKYKGKFVQ 4192
Query 4329 IPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
IP NDP+GF +RN VC VC MW+GYGC C LRE +Q+ D FLN
Sbjct 4193 IPLVGVNDPIGFCIRNVVCAVCNMWQGYGCPCSSLREINLQARD-ECFLNE 4242
Score = 288 bits (738), Expect = 8e-76, Method: Compositional matrix adjust.
Identities = 326/1183 (28%), Positives = 514/1183 (43%), Gaps = 143/1183 (12%)
Query 28 VRGFGDSVEEALSEAREHLKNGTCGLVELEKGV--LPQLEQPYVFIKRSDALSTNHG-HK 84
V G+ +EEAL A++ L+ LV + + P + V I S +TN G
Sbjct 29 VTGWDIPIEEALEYAKQQLRTPEPQLVFVPYYLSHAPGISGDRVVITDSIWYATNFGWQP 88
Query 85 VVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYR-NVLLRKNGNKGAGGHSYGIDLKSY 143
+ EL + DG++YGR G T GVL+P + I ++ +RK G G +S L +
Sbjct 89 IRELAMDKDGVRYGRGG-THGVLLPMQDPSFIMGDIDIQIRK---YGIGANSPPDVLPLW 144
Query 144 DLGDELGTD--PIEDYEQNW---NTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPL 198
D + G D P D+ N K G L+ + DNN G +
Sbjct 145 DGFSDPGPDVGPYLDFPDNCCPTKPKAKRGGDVYLSDQYG-------FDNN-----GILV 192
Query 199 DCIKDFLARAGKSMCTLSEQLDYIESKRGV--YCCRDHEHEIAWFTERSDKSYEHQTPFE 256
+ + L KS TL + L + R Y D ++A R Q+ F
Sbjct 193 EPVMKLLGVI-KSDFTLEQLLAALGKYRTEDGYDLPDGYVKVAIKVGRKAVPVLKQSIFT 251
Query 257 IKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGR-IRSVYPVASPQECNNM 315
+ + P + +P ++ V K G +G+ + +V + S NN
Sbjct 252 VVGVTE-----QLVPGYYYPFSTSSVVEH---TKPTRGGPVGKTVEAV--MLSLYGTNNY 301
Query 316 HLST---LMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYLPTNAVVKMPCPA 372
+ +T +KC++CD W + CG E + ++C + V+K C
Sbjct 302 NPATPVARLKCSYCDYYGWTPLKDIGTVNCLCGAE---FQLTSSCVDAESAGVIKPGCVM 358
Query 373 CQDPEIGPEHSVADYHNHSNIETRLRKGGRTRC-FGGCVFAYVGCYNKRAYWVPRASADI 431
D G RL G RT FGG +++ +G N WVPRA + +
Sbjct 359 LLDKSPG---------------MRLIPGNRTYVSFGGAIWSPIGKVNGVTVWVPRAYSIV 403
Query 432 GSGHTGITGD-NVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSA-FID 489
H+G G + +N++L+E L I + D N A +A+ T A +
Sbjct 404 AGEHSGAVGSGDTVAINKELVEYLIE---GIRVDADTLDNPTCATFIANLDCDTKAPVVH 460
Query 490 TIKSLDYKSFKTIVESCGNYKVTKG-KPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIF 548
T++SL C K+ G KP+ + + L + Q A ++
Sbjct 461 TVESLQ--------GLCLANKIMLGDKPLP----TDEFHPFIVGL-AYHVQRACWYGALA 507
Query 549 ARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY-VTGGLVQ 607
+RT +A D R + ++ VY + + AY V +
Sbjct 508 SRTFEAFR----DFVRTEEERFAQFFGKVCAPINGCVYLAYTTGRVTLFSAYQVLNTAIA 563
Query 608 QTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAW----EILKFLITGVFDIVKGQ 663
++ + V+ L+PI EW+ K+S K AW E L L F +VKG+
Sbjct 564 KSKDAFGGVAAIVVDMLKPILEWVLKKMSIA----KGAWLPYAEGLLALFKAQFTVVKGK 619
Query 664 IQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQCIRG 723
Q ++ D++ + + V AG K+ +L G + KG+ +
Sbjct 620 FQFLRASLNSKCHSLCDLLTTIMSKLLTSVKWAGCKVDALYTGTYYYFSRKGVLTEVQLC 679
Query 724 KEQLQLLM-PLKAPKEVTFLEGDSHDTV-LTSEEVVLKNGELEALETPVDSFTNGAIVGT 781
++L LL+ P + EV L+GD V LT E+ G LE + D + GT
Sbjct 680 AKRLGLLLTPKQQKMEVEVLDGDFDAPVTLTDLELEECTGVLEEVFGASDV---KLVKGT 736
Query 782 PVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVR 841
V + + + +D Y + G + FRL+GG + VTFG++ V + V
Sbjct 737 LVSLASKLFVRTEDGFLYRYVKSGGV-LGKAFRLRGGG-VSKVTFGDEEVHTIPNTVTVN 794
Query 842 ITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTN-----MGI 896
++++ E +D +L++ + + VE GT++ + ACVV +AV + L SDL ++ I
Sbjct 795 FSYDVCEGLDAILDKVMAPFQVEEGTKLEDLACVVQKAVYERL---SDLFSDCPAELRPI 851
Query 897 DLDEWSVATFYLFDDAGEENFSSRMYCSF---YPPDEEEEDDAECEEEEIDETCEHEYGT 953
+L+++ + +++ E+ MY S P D+E DD I++T E +
Sbjct 852 NLEDFLTSECFVYSKDYEKILMPEMYFSLEDAVPVDDEMVDD-------IEDTVEQASDS 904
Query 954 EDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLT 1013
+D + G +E ED D+T + ++ TP GY K+
Sbjct 905 DDQWLG---------------DEGAED-CDNTIQDVDVATS-MTTP-------CGYTKIA 940
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNG 1073
++V IKC DIV+EA++ + V+VNAAN++L HGGGVAGALN+ATN AMQKES +YIK NG
Sbjct 941 EHVYIKCADIVQEARNYSYAVLVNAANVNLHHGGGVAGALNRATNNAMQKESSEYIKANG 1000
Query 1074 PLTVGGSCLLSGHNLAKK-CLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIF 1132
L GG LLS H LA LHVVGP+ G+D+ LL A Y + D +L PL+SAGIF
Sbjct 1001 SLQPGGHVLLSSHGLASHGILHVVGPDKRLGQDLALLDAVYAAYTGFDSVLTPLVSAGIF 1060
Query 1133 GAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPR 1175
G +SL V+ V Y+ V D+ LYE+ + D P+
Sbjct 1061 GFTVEESLCSLVKNVACTTYVVVYDRQLYERALATSFDVPGPQ 1103
>sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respiratory
syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=1a PE=1 SV=1
Length=4391
Score = 2184 bits (5658), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1240/3286 (38%), Positives = 1870/3286 (57%), Gaps = 196/3286 (6%)
Query 1235 INGKLYHDSQNMLRGEDMSFLEKDAPYMVGD-VITSG-----DITCVVIPSKKAGGTTEM 1288
I G + S+ ++ E ++ P VGD V+ G +I VV P +A +
Sbjct 1156 IAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSL 1215
Query 1289 LSR---ALKKVPVDEYITTYPGQGCAG--------YTLEEAKTALKKCKSAFYVLPSEAP 1337
LS+ A+ P+ +T G G Y + EAKT + ++ V S
Sbjct 1216 LSKCYKAMNAYPL--VVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTI 1273
Query 1338 NAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVR 1397
+ L LR + A++ + +C D A ++ K + VD GV+
Sbjct 1274 VDIPQSLTFSYDGLRGAIRKAKDYGFTVFVCTDNSANTKVLRNKGVDYTKKFLTVD-GVQ 1332
Query 1398 FFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPD 1457
++ YTSK+ + I+ + N + +++MP+GYV+HG +L +A +R + P V +++ +
Sbjct 1333 YYCYTSKDTLDDILQQANK-SVGIISMPLGYVSHGLDLIQAGSVVRRVNVPYVCLLANKE 1391
Query 1458 AVTTYNGYLTSSSKTS-EEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKI------ 1510
++ K + E F++ V G Y W EL V+ L+ +
Sbjct 1392 QEAIL---MSEDVKLNPSEDFIKHVRTNGGYNSWHLV--EGELLVQDLRLNKLLHWSDQT 1446
Query 1511 ------VYHTLESPVEFHLDGEVLSLDKLKSLLSLREVK--TIKVFTTVDNTNLHTQLVD 1562
V++ +++ F + +L ++ L R + TI+V TVD N T +++
Sbjct 1447 ICYKDSVFYVVKNSTAFPFE----TLSACRAYLDSRTTQQLTIEVLVTVDGVNFRTVVLN 1502
Query 1563 MSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFV---LPSDDTLRSEAFEYYHTLDESF 1619
TY Q G + +GAD++ P G + ++ L +D+T + E Y +D +F
Sbjct 1503 NKNTYRSQLGCVFFNGADISDTIPDEKQNGHSLYLADNLTADETKALK--ELYGPVDPTF 1560
Query 1620 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQL-EVKFNAPALQEAYYR 1678
L R+ S KWK + S+K +DNNCYL++V++ L L ++KF PALQ A+ +
Sbjct 1561 LHRFYSLKAAVHKWKMVVCDKVRSLKLSDNNCYLNAVIMTLDLLKDIKFVIPALQHAFMK 1620
Query 1679 ARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE-SAKRVLNVVCKHCGQKTT 1737
+ GD+ +F ALI+AY N T G D + +L A L SA+ V C CG K
Sbjct 1621 HKGGDSTDFIALIMAYGNCTFGAPDDASRLLHTVLAKAELCCSARMVWREWCNVCGIKDV 1680
Query 1738 TLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGT 1797
L G++A Y+G + ++L+ ++ C CG + + +V+ + ++++S P E + T
Sbjct 1681 VLQGLKACCYVGVQTVEDLRARMTYVCQCGGERHRQIVEHTTPWLLLSGTPNEKLVTTST 1740
Query 1798 ---FLCANEYTG-NYQCGHYTHITAKETL-YRIDGAHLTKMSEYKGPVTDVFYKETSYTT 1852
F+ N + G GHY H K L + D ++K S++K VTDV + Y++
Sbjct 1741 APDFVAFNVFQGIETAVGHYVHARLKGGLILKFDSGTVSKTSDWKCKVTDVLFPGQKYSS 1800
Query 1853 TIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYT-EQPIDLVPTQPLPNASFDNFKLTCSN 1911
V Y LDG TE++P L +Y KD Y+T E P+ P L + + N L S+
Sbjct 1801 DCNVVRYSLDGNFRTEVDPDLSAFYVKDGKYFTSEPPVTYSPATILAGSVYTNSCLVSSD 1860
Query 1912 TKFADD-----LNQMTGF--TKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLH 1964
+ D N + GF +KP +++ + +F P +GDV+ ++ Y +K GA
Sbjct 1861 GQPGGDAISLSFNNLLGFDSSKPVTKKYTYSFLPKEDGDVLLAEFDTYDPIYKNGAMYKG 1920
Query 1965 KPIVWHINQATTKTTF-KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQP 2023
KPI+W +N+A+ T K N LR ++ P++ N F L+VE T P
Sbjct 1921 KPILW-VNKASYDTNLNKFNRASLRQIFDVAPIELENKFTPLSVEST------------P 1967
Query 2024 TSEEVVENPTIQKE--VIECD-VKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVE-N 2079
V+ +Q+E +++C + V NV D G V + L EDL YV+
Sbjct 1968 VEPPTVDVVALQQEMTIVKCKGLNKPFVKDNVSFVADDSGTPVVEYLSKEDLHTLYVDPK 2027
Query 2080 TSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAI----------- 2128
+ + K N LS L L T+ + IN V S L L +A+
Sbjct 2028 YQVIVLKDNVLSSMLRLHTVES---GDINVVAASGSLTRKVKLLFRASFYFKEFATRTFT 2084
Query 2129 ---TTSNCAKRLAQRV---------FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTT-- 2174
+C K + + + +++ +F L + +K + ++ S T
Sbjct 2085 ATTAVGSCIKSVVRHLGVTKGILTGCFSFVKMLFMLPLAYFSDSKLGTTEVKVSALKTAG 2144
Query 2175 -IAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSN 2233
+ N VK +D ++ ++ + + + L + L S+ + VL S+
Sbjct 2145 VVTGNVVKQCCTAAVDLSMDKLRRVDWKSTLRLLLMLCTTMVLLSSVYHLYVFNQVLSSD 2204
Query 2234 -------------------FGAPSYCNGVRELY-LNSSNVTTMDFCEG-SFPCSICLSGL 2272
G S C+G+ Y NS +V T FC S C+ CL
Sbjct 2205 VMFEDAQGLKKFYKEVRAYLGISSACDGLASAYRANSFDVPT--FCANRSAMCNWCLISQ 2262
Query 2273 DSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGY-- 2330
DS+ YPAL+ +Q +S Y L++ L A E LAYML+T F L L+ + FF
Sbjct 2263 DSITHYPALKMVQTHLSHYVLNIDWLWFAFETGLAYMLYTSAFNWLLLAGTLHYFFAQTS 2322
Query 2331 ----FASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTC 2386
+ S+ + S W I P++ +VRMY A + + K Y H+++GC + C
Sbjct 2323 IFVDWRSYNYAVSSAFWLFTHI----PMAGLVRMYNLLACLWLLRKFYQHVINGCKDTAC 2378
Query 2387 MMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEV 2446
++CYKRNR TRVE +T+V G KR+FY+ ANGG FC+ HNWNC++CDT G+TFI +EV
Sbjct 2379 LLCYKRNRLTRVEASTVVCGGKRTFYITANGGISFCRRHNWNCVDCDTAGVGNTFICEEV 2438
Query 2447 ARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLR- 2505
A DL+ +RPIN TD+S Y VDSV VK + + + GQ YER PL F NLD L+
Sbjct 2439 ANDLTTALRRPINATDRSHYYVDSVTVKETVVQFNYRRDGQPFYERFPLCAFTNLDKLKF 2498
Query 2506 ---ANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTE 2562
T G N I++D + ES ++SA VYYSQ++C+ ILL+D +LV+ VGDS+E
Sbjct 2499 KEVCKTTTGIPEYNFIIYDSSDRGQESLARSACVYYSQVLCKSILLVDSSLVTSVGDSSE 2558
Query 2563 VSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGV-VDT 2621
++ KMFD++V++F + ++V +KL+ L++TA + +G VL+TF+ AAR V++
Sbjct 2559 IATKMFDSFVNSFVSLYNVTRDKLEKLISTARDGVRRGDNFHSVLTTFIDAARGPAGVES 2618
Query 2622 DVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVA 2681
DV+T ++++ ++ +H D+++T +S NN++ +Y K ++++ DLG+ IDCNA +N V
Sbjct 2619 DVETNEIVDSVQYAHKHDIQITNESYNNYVPSYVKPDSVSTSDLGSLIDCNAASVNQIVL 2678
Query 2682 KSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGK 2741
++ N + IWN YM LS+ L++QIR A +K N+ FRLT + R N+++ + + K
Sbjct 2679 RNSNGACIWNAAAYMKLSDALKRQIRIACRKCNLAFRLTTSKLRANDNILSVRFT--ANK 2736
Query 2742 IVSTC-----------FKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
IV K + AT++ L A++ Y+ +P ++ + Y + I+ +K +
Sbjct 2737 IVGGAPTWFNALRDFTLKGYVLATIIVFLCAVLMYLCLPTFSMVPVEFYEDRILDFKVLD 2796
Query 2791 DGVTRDIISTDDCFANKHAGFDAWFSQR-GGSYKNDKSCPVVAAIITREIGFIVPGLPGT 2849
+G+ RD+ D CFANKH F W+ + GG Y N +CP+ A+I G +P +P T
Sbjct 2797 NGIIRDVNPDDKCFANKHRSFTQWYHEHVGGVYDNSITCPLTVAVIAGVAGARIPDVP-T 2855
Query 2850 VLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPY 2909
L +N + F+ RVF+ G++CYTP I Y F+ S C+L +ECT+F+DA G+ PY
Sbjct 2856 TLAWVNNQIIFFVSRVFANTGSVCYTPIDEIPYKSFSDSGCILPSECTMFRDAEGRMTPY 2915
Query 2910 CYDTNLLEGSISYSELRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDAEYCRHGTCER 2968
C+D +L G+ +YS++RP RY L DG++ I+FP E ++R+ T +YCR G+CE
Sbjct 2916 CHDPTVLPGAFAYSQMRPHVRYDLYDGNMFIKFPEVVFESTLRITRTLSTQYCRFGSCEY 2975
Query 2969 SEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGG 3028
++ G+C++T+G W + N+H+ GV+CG D ++++ + L QP+ ++ S+V G
Sbjct 2976 AQEGVCITTNGSWAIFNDHHLNRPGVYCGSDFIDIVRRLAVSLFQPITYFQLTTSLVLGI 3035
Query 3029 IIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLY 3088
+ +T YY K +R F +Y + +++ +C V + Y+ Y Y
Sbjct 3036 GLCAFLTLLFYYINKVKRAFADYTQCAVIAVVAAVLNSLCICFVASIPLCIVPYTALYYY 3095
Query 3089 LTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRK--RVMFNG 3146
TFYFTN+ +F+ H+ W+ MF PIVP W+T +Y + +H W + +K V +G
Sbjct 3096 ATFYFTNEPAFIMHVSWYIMFGPIVPIWMTCVYTVAMCFRHFFWVLAYFSKKHVEVFTDG 3155
Query 3147 VTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREA 3206
+F++AA F++NK+ Y LR+ L Y+R+L L+NKYKYFSGA++T +YREA
Sbjct 3156 KLNCSFQDAASNIFVINKDTYAALRNS--LTNDAYSRFLGLFNKYKYFSGAMETAAYREA 3213
Query 3207 ACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT 3266
A CHLAKAL +S +G+D+LYQPP SITS VLQSG KM+ PSG VE CMVQVTCG+ T
Sbjct 3214 AACHLAKALQTYSETGSDLLYQPPNCSITSGVLQSGLVKMSHPSGDVEACMVQVTCGSMT 3273
Query 3267 LNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQ---AGNVQLRVIGHSMQ 3323
LNGLWLD+TV+CPRHV+C A+ + +PNY+ LLI +NHSF VQ LRV+GH+MQ
Sbjct 3274 LNGLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGHAMQ 3333
Query 3324 NCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNG 3383
LL+L VD +NP TP Y F ++PG FSVLACYNG P+G + MRPN+TIKGSFL G
Sbjct 3334 GTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSFLCG 3393
Query 3384 SCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLN 3443
SCGSVG+ + ++FCYMH MEL G H G+ +G YG F+D+Q Q TD ++N
Sbjct 3394 SCGSVGYTKEGSVINFCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYCSVN 3453
Query 3444 VLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY-EPLTQDHVDILGPLSAQTGIAVL 3502
V+AWLYAA++NG WF+ T++ FN A+ + E + VD+L + +TG+A+
Sbjct 3454 VVAWLYAAILNGCAWFVKPNRTSVVSFNEWALANQFTEFVGTQSVDML---AVKTGVAIE 3510
Query 3503 DMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLL 3562
+ A+++L G G+ ILGST+LEDEFTP DV Q GV Q +K+ GT HW+
Sbjct 3511 QLLYAIQQLY-TGFQGKQILGSTMLEDEFTPEDVNMQIMGVVMQSGVRKVTYGTAHWLFA 3569
Query 3563 TFLTSLLILVQSTQWSLFFFVYEN---AFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLP 3619
T +++ +I++Q+T+++L+ +++E P MA MLLVKHKH FL LFLLP
Sbjct 3570 TLVSTYVIILQATKFTLWNYLFETIPTQLFPLLFVTMAFV---MLLVKHKHTFLTLFLLP 3626
Query 3620 SLATVAYFNMVYMP----ASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTAR 3675
+ Y N+VY P +S ++ + WL + + D +Y S ++L+++ R
Sbjct 3627 VAICLTYANIVYEPTTPISSALIAVANWLAPTNAYMRTTH-TDIGVYISMSLVLVIVVKR 3685
Query 3676 TVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAI 3735
+ L + + +Y G A I+ V ++TS+Y+ V + LA+
Sbjct 3686 LYNPSLSNFALALCSGVMWLYTYSIGEA-SSPIAYLVFVTTLTSDYTITVFVTVNLAKVC 3744
Query 3736 VFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQ 3795
+ Y P L + ++ I+L+Y LG+ C CYFG+F LLN R +GVYD+ VSTQ
Sbjct 3745 TYAIFAYSPQLTLVFPEVKMILLLYTCLGFMCTCYFGVFSLLNLKLRAPMGVYDFKVSTQ 3804
Query 3796 EFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQ 3855
EFR+M + L P++S +A LN KL+GIGG PCIKVA +QSK++D+KCTSVVLLSVLQQ
Sbjct 3805 EFRFMTANNLTAPRNSWEAMALNFKLIGIGGTPCIKVAAMQSKLTDLKCTSVVLLSVLQQ 3864
Query 3856 LRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNR 3915
L +E++S+ WA CV+ HNDIL A D +EAFEK VSL + L++ G VD++ L ++ D
Sbjct 3865 LHLEANSRAWAFCVKCHNDILAATDPSEAFEKFVSLFATLMTFSGNVDLDALASDIFDTP 3924
Query 3916 ATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAM 3974
+ LQA SEFS L ++A AQ+AY++A+ +GD S VLK L+K++N+AK+ +++D A+
Sbjct 3925 SVLQATLSEFSHLATFAELEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAV 3984
Query 3975 QRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCV 4034
RKLE+MADQAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+
Sbjct 3985 ARKLERMADQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCI 4044
Query 4035 PLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD 4094
PL++IPL + KL VV+PD+ + + YA ALW+I + + D++IV+ S++ +D
Sbjct 4045 PLSVIPLCASNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VD 4103
Query 4095 NSPNLAWPLIVTALRAN-SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSK 4153
++ NL WPL++ RA+ SAVKLQNNE+ P L+ M +AG QT C + ++LAYY +
Sbjct 4104 SNENLTWPLVLECTRASTSAVKLQNNEIKPSGLKTMVVSAGQEQTNC-NTSSLAYYEPVQ 4162
Query 4154 GGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNN 4213
G + ++ALLSD+ LKWAR DG ++ EL+PPC+F+ PKGP+++YLYF+K LNN
Sbjct 4163 GRKMLMALLSDNAYLKWARVEGKDGFVSV--ELQPPCKFLIAGPKGPEIRYLYFVKNLNN 4220
Query 4214 LNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVK 4273
L+RG VLG +AATVRLQAG+ TE +NS+VLS F VDP KAY D++ +GG P+TNCVK
Sbjct 4221 LHRGQVLGHIAATVRLQAGSNTEFASNSSVLSLVNFTVDPQKAYLDFVNAGGAPLTNCVK 4280
Query 4274 MLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTC 4333
ML TGTG AI+V PE+ DQE++GGAS CLYCR HI+HP+ G C KGK+VQIP C
Sbjct 4281 MLTPKTGTGIAISVKPESTADQETYGGASVCLYCRAHIEHPDVSGVCKYKGKFVQIPAQC 4340
Query 4334 ANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
DPVGF L NT C VC W GYGC+CD LR+ + + S FLN
Sbjct 4341 VRDPVGFCLSNTPCNVCQYWIGYGCNCDSLRQAALPQSKDSNFLNE 4386
Score = 305 bits (782), Expect = 6e-81, Method: Compositional matrix adjust.
Identities = 314/1190 (26%), Positives = 519/1190 (44%), Gaps = 163/1190 (14%)
Query 101 GITLGVLVPHVGETPIAYRNVLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQN 160
G +G+ P+ E +N+LLRK G GG+ Y Y+ + + ++D+E +
Sbjct 123 GKPIGMFFPYDIELVTGKQNILLRKYGR---GGYHY--TPFHYERDNTSCPEWMDDFEAD 177
Query 161 WNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAG-KSMCTLSEQL 219
K+ L++L GG VT VD CG DG P+ +A+ G + + +
Sbjct 178 PKGKYAQNLLKKLI----GGDVTP-VDQYMCGVDGKPISAYAFLMAKDGITKLADVEADV 232
Query 220 DYIESKRGVYCCRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNS 279
G +++ + + W ER D Y Q+ F I S + D + P + F L
Sbjct 233 AARADDEGFITLKNNLYRLVWHVERKDVPYPKQSIFTINSVVQKDGVENTPPHY-FTLGC 291
Query 280 KVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNN---MHLSTLMKCNHCDEVSWQTCDF 336
K+ + PR + + + +Y + N ++ S ++C C SW T +
Sbjct 292 KILTLTPRNKWSGVSDLSLKQKLLYTFYGKESLENPTYIYHSAFIECGSCGNDSWLTGNA 351
Query 337 LKATCEHCGTENLVIEGPT-TCGYLPTNAVVKMPCPACQDPEIGP--EHSVADYHNHSNI 393
++ CG + + G + NA++ CP + +HSVA ++ +
Sbjct 352 IQGFACGCGASYTANDVEVQSSGMIKPNALLCATCPFAKGDSCSSNCKHSVAQLVSYLSE 411
Query 394 ETRLRKGGR--TRCFGGCVFAYVGCYNKRAYWVPRASADIG----SGHTGITG--DNVET 445
+ + T FGG +AY GC Y+VPRA + + S TG TG + V
Sbjct 412 RCNVIADSKSFTLIFGGVAYAYFGCEEGTMYFVPRAKSVVSRIGDSIFTGCTGSWNKVTQ 471
Query 446 LNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVES 505
+ LE + + ++N VG+F +N+ V IL+ + + +K + + +
Sbjct 472 IANMFLE---QTQHSLNFVGEFVVNDVVLAILSGTTTNVDKIRQLLKGVTLDKLRDYLAD 528
Query 506 CGNYKVTKGKPVKGAWNIG----QQRSVLTP---LCGFPSQAAGV------IRSIFARTL 552
+ VT G + A N+G Q ++ P L G V + + TL
Sbjct 529 Y-DVAVTAGPFMDNAINVGGTGLQYAAITAPYVVLTGLGESFKKVATIPYKVCNSVKDTL 587
Query 553 DAANHSIPDLQRAAVTILD-GISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQ 611
HS+ L R +D G+S S L D + DL SV ++ L +T
Sbjct 588 TYYAHSV--LYRVFPYDMDSGVSSFSELLFDCV----DL---SVASTYFLVRLLQDKTGD 638
Query 612 WLSNLLG---TTVEKL-RPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVA 667
++S ++ T V KL FE EA + FL D + + + + V
Sbjct 639 FMSTIITSCQTAVSKLLDTCFEATEATFN----FLLDLAGLFRIFLRNAYVYTSQGFVVV 694
Query 668 SDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLG--EVFIAQSKGLYRQCIRGK- 724
+ + VK +D++NK +++ +V+ AG+ + ++ E I S Y + K
Sbjct 695 NGKVSTLVKQVLDLLNKGMQLLHTKVSWAGSNISAVIYSGRESLIFPSGTYYCVTTKAKS 754
Query 725 --EQLQLLMPLK-APKEVTFLEGDSHDTVLTSE------EVVLKNGELEALETPVDSFTN 775
+ L +++P + + K++ L+ + T ++ E V+ E + +P
Sbjct 755 VQQDLDVILPGEFSKKQLGLLQPTDNSTTVSVTVSSNMVETVVGQLEQTNMHSP------ 808
Query 776 GAIVGTPVCVNGLMLLEIKDKEQYCALSPGLL---ATNNVFRLKGGAPIKGVTFGEDTVW 832
IVG V ++ + + K+++ + A P A +FRLKGGAP+K V FG D V
Sbjct 809 DVIVGDYVIISEKLFVRSKEEDGF-AFYPACTNGHAVPTLFRLKGGAPVKKVAFGGDQVH 867
Query 833 EVQGYKNVRITFELDERVDKVL-NEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLL 891
EV ++V + + + +D +L + + V+ + EFA VV E V L LL
Sbjct 868 EVAAVRSVTVEYNIHAVLDTLLASSSLRTFVVDKSLSIEEFADVVKEQVSDLL---VKLL 924
Query 892 TNMGI---DLDEWSVATFYLFDDAGEENFSSRMYCSFYPP--DEE---------EEDDAE 937
M I DLD++ A Y F+ G+ ++SS M S +P DEE EE ++E
Sbjct 925 RGMPIPDFDLDDFIDAPCYCFNAEGDASWSSTMIFSLHPVECDEECSEVEASDLEEGESE 984
Query 938 CEEEEIDETCEHEYGTEDDY------QGLPLEFGASAETVRVEEEEE------------- 978
C E E + + DD + PL+ A T V+EE +
Sbjct 985 CISETSTEQVDVSHEISDDEWAAAVDEAFPLD-EAEDVTESVQEEAQPVEVPVEDIAQVV 1043
Query 979 -EDWLDDT---TEQSEIEPEPEPTPEEP-------------------------------- 1002
D L +T ++ E+ P+ P EP
Sbjct 1044 IADTLQETPVVSDTVEVPPQVVKLPSEPQTIQPEVKEVAPVYEADTEQTQSVTVKPKRLR 1103
Query 1003 ----VNQFTGYLK--LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKA 1056
V+ + + +T+ V I D ++ A+ V+VNAAN HLKHGGG+AGA+N A
Sbjct 1104 KKRNVDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNAANTHLKHGGGIAGAINAA 1163
Query 1057 TNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF 1116
+ GA+QKESD+YI GPL VG S LL GH+LAK LHVVGP+ A +D+ LL Y+
Sbjct 1164 SKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGPDARAKQDVSLLSKCYKAM 1223
Query 1117 NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVM 1166
N+ +++ PL+SAGIFG KP S ++ +T+V + VN + +Y+ + +
Sbjct 1224 NAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQDVYKSLTI 1273
>sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=1a PE=3 SV=1
Length=4383
Score = 1887 bits (4888), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1100/2889 (38%), Positives = 1632/2889 (56%), Gaps = 131/2889 (5%)
Query 1545 IKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL 1604
+ + TVD N + V + +G+ G + DG +VTK K +N++GK FF D L
Sbjct 1565 VDILLTVDGVNFTNRFVPVGENFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQF---DNL 1621
Query 1605 RSE---AFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
SE A D+ L Y + L + KW+ G + K A+NNC+++ L LQ
Sbjct 1622 SSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQ 1681
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
L +KF QEA+ R+G A F +L+LA G+ D R+ + + +L A
Sbjct 1682 SLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGA 1741
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
+ CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG+ + V+ + F
Sbjct 1742 ICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPF 1799
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S PA KL +G AN + G+ + GHY H+ +++ D +++ K+++ G ++
Sbjct 1800 LICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLS 1857
Query 1842 DVFYKETSYTTTIKPV--SYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLP 1898
D Y + + T K V +Y LD V E +P L YY YYT++ I T
Sbjct 1858 DCLYLK-NLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKV 1916
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL D LN GF + E VT +P GDVV Y ++
Sbjct 1917 DGVYTNFKLI--GHTICDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYE 1974
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFEVLAVEDTQGMDNL 2016
+G KP++W ++ + + + +P+ N F+VL V+D ++
Sbjct 1975 RGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFDVLKVDDVDDGGDI 2025
Query 2017 ACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAY 2076
+ ES S+E+ I+ ++ K +V +VI+ +K + L D+ +
Sbjct 2026 S-ESDAKESKEI---NIIKLSGVK---KPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMW 2078
Query 2077 VENTSITIKKPNELSLALGLKTI---ATHGIAAINSVPWSKI-LAYVKPFLGQAAITTSN 2132
+ ++ N+LS+A+ + TI G+ + S+P + L +KP N
Sbjct 2079 LTGCRYVVRTANDLSMAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVF--------N 2129
Query 2133 CAKRLAQRVFN--NYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
K + ++ N++ ++F LLF + + T +A K KL A
Sbjct 2130 VVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---KLTCKLVALA 2182
Query 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSYCNGVRELYL 2248
N + K+S + A + + + + I F L G P++ + +
Sbjct 2183 FKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIAQWIK 2242
Query 2249 NSSNVTTM-------------DFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK-LD 2294
++ ++ T+ +C GS C CL+G D LD+Y A++ +Q +D
Sbjct 2243 STFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVD 2302
Query 2295 LT-ILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQM 2351
T +L + E +++Y L+T +FY L +Q+ + F+ ++ W + ++S+ M
Sbjct 2303 YTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLANM 2362
Query 2352 APVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSF 2411
P +R YI ASF ++ + H+ GC+ C+ CYKRNR+ RV+C+TIV GM R +
Sbjct 2363 LPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIRYY 2422
Query 2412 YVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2471
V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V V
Sbjct 2423 DVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTDV 2482
Query 2472 AVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAS 2531
+ L++++ GQ+TY+ S FV+ NL + KG ++V+V + + D++
Sbjct 2483 KQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVENDA--DKANF 2540
Query 2532 KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVA 2591
+A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V + L AL+A
Sbjct 2541 LNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIA 2600
Query 2592 TAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNF 2650
TAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE+T +SCNN
Sbjct 2601 TAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCNNL 2660
Query 2651 MLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAA 2710
+ TY K +N+ DLG I +A+H+ VAK VS IW+V + LS + +++ A
Sbjct 2661 VPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKAC 2720
Query 2711 KKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYI---- 2766
K + +LT V+V+TT SLKGG + S +C L +LVC+I
Sbjct 2721 CKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSY-------FVYVCFLLSLVCFIGLWC 2773
Query 2767 VMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKN 2824
+MP +T+ D YK + +GV RD+ D CFANK FD W+ G Y N
Sbjct 2774 LMPTYTVHKSDFQLPVYTSYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2825 DKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSD 2884
+CP+V A++ +++G V +P VLR LHF+ SA G CYTP I YS+
Sbjct 2834 SMACPIVVAVVDQDLGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2885 FATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SIIQFPN 2943
F S CVL++ CT+F A G P PYCY L++ + YS L P RY L + I+FP
Sbjct 2893 FYASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGFIRFPE 2952
Query 2944 TYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNL 3003
EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG D +L
Sbjct 2953 VLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3004 IANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFL 3063
I +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWC 3072
Query 3064 MSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVF 3123
++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W +Y+
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIS 3132
Query 3124 CISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNR 3183
+ H W F Y R R+ + + TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVF-AYCR-RLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3184 YLALYNKYKYFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSG 3242
YL+LYNKY+Y+SG +DT +YREAAC LAKA++ F+ N+G+DVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3243 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKS 3302
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3303 NHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSP 3362
+ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3363 SGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFY 3422
G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3423 GPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3482
GP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQV 3488
Query 3483 TQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSG 3542
D V + L++ TG+++ + AA+K L+NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3543 VTFQGKFKKIVKGTHHWMLL-TFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAAC 3601
+ Q K ++VKG W++ TFL S I+ +W++F +V N L T + + +
Sbjct 3546 IKLQSKRTRLVKGIVCWIMASTFLFS-CIITAFVKWTMFMYVTTN-MLSITFCALCVISL 3603
Query 3602 AMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCV 3660
AMLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y D V
Sbjct 3604 AMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEV 3662
Query 3661 MYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3719
+Y L++ ++ +T R++ D + + VI++V Y G+ L++ I + ++ S+
Sbjct 3663 IYGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFG 3720
Query 3720 NYSGVVTTIMFLARAIV-FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLN 3778
Y+ M A+ I +V V L F ++ +++ Y F+GY CY+GLF L+N
Sbjct 3721 TYTWTTALSMAAAKVIAKWVAVNV--LYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMN 3778
Query 3779 RYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSK 3838
FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+ QSK
Sbjct 3779 SLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSK 3838
Query 3839 MSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSM 3898
++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL +
Sbjct 3839 LTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFAN 3898
Query 3899 QGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-E 3951
AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G + +
Sbjct 3899 PAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGSANQ 3958
Query 3952 VVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLF 4011
LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF
Sbjct 3959 QQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLF 4018
Query 4012 TMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASA 4071
+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TYA
Sbjct 4019 SMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGN 4078
Query 4072 LWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQM 4129
+W+IQ + D+D QL+EI S + WPL++ A R N SA LQNNEL P L+
Sbjct 4079 VWQIQTIQDSDGTNKQLNEI----SDDCNWPLVIIANRHNEVSATVLQNNELMPAKLKTQ 4134
Query 4130 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4189
+G QT T YYNNS G+ V A+LSD LK+ + K DG + EL+PP
Sbjct 4135 VVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPP 4191
Query 4190 CRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAF 4249
C+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF
Sbjct 4192 CKFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAF 4251
Query 4250 AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC 4309
+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+YCR
Sbjct 4252 SVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIYCRA 4311
Query 4310 HIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQ 4369
++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +Q
Sbjct 4312 RVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQ 4369
Query 4370 SADASTFLN 4378
S D + FLN
Sbjct 4370 SKD-TNFLN 4377
Score = 83.6 bits (205), Expect = 8e-14, Method: Compositional matrix adjust.
Identities = 51/155 (33%), Positives = 78/155 (50%), Gaps = 2/155 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPN--LNAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
GIF SL + T QV + N++ ++ +
Sbjct 1393 GIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFDLI 1427
Score = 73.6 bits (179), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 77/286 (27%), Positives = 129/286 (45%), Gaps = 36/286 (13%)
Query 729 LLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVC- 784
L MP KA ++ +L+G D L V + L TP ++ V +C
Sbjct 763 LTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSL----TPC-GYSEPPKVADKICI 817
Query 785 VNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-KNVRI 842
V+ + + + DK + + + +R+ + VTF E TV E+ K +++
Sbjct 818 VDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAG--RRVTFKEQPTVNEIASTPKTIKV 875
Query 843 TFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLL---TNMGIDLD 899
+ELD+ + +LN C V+ V+ ++ EF VV +A+ + L P +L + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVVDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 900 EWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQG 959
+ + +LFD+AGEE +S++YC+F P EDD EE ++E T+
Sbjct 936 KLEDNSLFLFDEAGEEVLASKLYCAFTAP----EDDDFLEESGVEEDDVEGEETD----- 986
Query 960 LPLEFGASAETVRVEEEEE-----EDWLDD----TTEQSEIEPEPE 996
L ++ E E+EE ED LDD T S++E + E
Sbjct 987 --LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVE 1030
>sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=1a PE=3 SV=1
Length=4383
Score = 1885 bits (4883), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1100/2889 (38%), Positives = 1631/2889 (56%), Gaps = 131/2889 (5%)
Query 1545 IKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL 1604
+ + TVD N + V + ++G+ G + DG +VTK K +N++GK FF D L
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQF---DNL 1621
Query 1605 RSE---AFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
SE A D+ L Y + L + KW+ G + K A+NNC+++ L LQ
Sbjct 1622 SSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQ 1681
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
L +KF QEA+ R+G A F +L+LA G+ D R+ + + +L A
Sbjct 1682 SLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGA 1741
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
+ CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG+ + V+ + F
Sbjct 1742 ICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPF 1799
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S PA KL +G AN + G+ + GHY H+ +++ D +++ K+++ G ++
Sbjct 1800 LICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLS 1857
Query 1842 DVFYKETSYTTTIKPV--SYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLP 1898
D Y + + T K V +Y LD V E P L YY YYT++ I T
Sbjct 1858 DCLYLK-NLKQTFKSVLTTYYLDDVKKIEYNPDLSQYYCDGGKYYTQRIIKAQFKTFEKV 1916
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL D LN GF + E VT +P GDVV Y ++
Sbjct 1917 DGVYTNFKLI--GHTICDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYE 1974
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFEVLAVEDTQGMDNL 2016
+G KP++W ++ + + + +P+ N F+VL V+D ++
Sbjct 1975 RGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFDVLKVDDVDDGGDI 2025
Query 2017 ACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAY 2076
+ ES S+E+ I+ ++ K +V +VI+ +K + L D+ +
Sbjct 2026 S-ESDAKESKEI---NIIKLSGVK---KPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMW 2078
Query 2077 VENTSITIKKPNELSLALGLKTI---ATHGIAAINSVPWSKI-LAYVKPFLGQAAITTSN 2132
+ ++ N LS+A+ + TI G+ + S+P + L +KP N
Sbjct 2079 LTGCRYVVRTANALSMAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVF--------N 2129
Query 2133 CAKRLAQRVFN--NYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
K + ++ N++ ++F LLF + + T +A K KL A
Sbjct 2130 VVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---KLTCKLVALA 2182
Query 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSYCNGVRELYL 2248
N + K+S + A + + + + I F L G P++ + +
Sbjct 2183 FKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIAQWIK 2242
Query 2249 NSSNVTTM-------------DFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK-LD 2294
++ ++ T+ +C GS C CL+G D LD+Y A++ +Q +D
Sbjct 2243 STFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVD 2302
Query 2295 LT-ILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQM 2351
T +L + E +++Y L+T +FY L +Q+ + F+ ++ W + ++S+ M
Sbjct 2303 YTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLANM 2362
Query 2352 APVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSF 2411
P +R YI ASF ++ + H+ GC+ C+ CYKRNR+ RV+C+TIV GM R +
Sbjct 2363 LPAHVFMRFYIIIASFIKLFILFRHVAYGCSKPGCLFCYKRNRSLRVKCSTIVGGMIRYY 2422
Query 2412 YVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV 2471
V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V V
Sbjct 2423 DVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTDV 2482
Query 2472 AVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESAS 2531
+ L++++ GQ+TY+ S FV+ NL + KG ++V+V + + D++
Sbjct 2483 KQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVENDA--DKANF 2540
Query 2532 KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVA 2591
+A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V + L AL+A
Sbjct 2541 LNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIA 2600
Query 2592 TAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNF 2650
TAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE+T +SCNN
Sbjct 2601 TAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCNNL 2660
Query 2651 MLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAA 2710
+ TY K +N+ DLG I +A+H+ VAK VS IW+V + LS + +++ A
Sbjct 2661 VPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKAC 2720
Query 2711 KKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYI---- 2766
K + +LT V+V+TT SLKGG + S +C L +LVC+I
Sbjct 2721 CKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSY-------FVYVCFLLSLVCFIGLWC 2773
Query 2767 VMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKN 2824
+MP +T+ D YK + +GV RD+ D CFANK FD W+ G Y N
Sbjct 2774 LMPTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSN 2833
Query 2825 DKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSD 2884
+CP+V A++ +++G V +P VLR LHF+ SA G CYTP I YS+
Sbjct 2834 SMACPIVVAVVDQDLGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQISYSN 2892
Query 2885 FATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SIIQFPN 2943
F S CVL++ CT+F A G P PYCY L++ + YS L P RY L + I+FP
Sbjct 2893 FYASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGFIRFPE 2952
Query 2944 TYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNL 3003
EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG D +L
Sbjct 2953 VLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDL 3012
Query 3004 IANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFL 3063
I +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N +++
Sbjct 3013 IYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVWC 3072
Query 3064 MSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVF 3123
++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W +Y+
Sbjct 3073 VNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIS 3132
Query 3124 CISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNR 3183
+ H W F Y R R+ + + TFEE AL TF++ K+ Y KL++ L +NR
Sbjct 3133 VVVSNHAFWVF-AYCR-RLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNR 3188
Query 3184 YLALYNKYKYFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSG 3242
YL+LYNKY+Y+SG +DT +YREAAC LAKA++ F+ N+G+DVLYQPP S++++ LQSG
Sbjct 3189 YLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSG 3248
Query 3243 FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKS 3302
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +LL R +
Sbjct 3249 IVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVT 3308
Query 3303 NHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSP 3362
+ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P
Sbjct 3309 SSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKP 3368
Query 3363 SGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFY 3422
G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD G FY
Sbjct 3369 QGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDFNGDFY 3428
Query 3423 GPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPL 3482
GP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3429 GPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQV 3488
Query 3483 TQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSG 3542
D V + L++ TG+++ + AA+K L+NG GR I+GS EDE TP DV +Q +G
Sbjct 3489 KSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAG 3545
Query 3543 VTFQGKFKKIVKGTHHWMLL-TFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAAC 3601
+ Q K ++VKG W++ TFL S I+ +W++F +V N L T + + +
Sbjct 3546 IKLQSKRTRLVKGIVCWIMASTFLFS-CIITAFVKWTMFMYVTTN-MLSITFCALCVISL 3603
Query 3602 AMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCV 3660
AMLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y D V
Sbjct 3604 AMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEV 3662
Query 3661 MYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3719
+Y L++ ++ +T R++ D + + VI++V Y G+ L++ I + ++ S+
Sbjct 3663 IYGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFG 3720
Query 3720 NYSGVVTTIMFLARAIV-FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLN 3778
Y+ M A+ I +V V L F ++ +++ Y F+GY CY+GLF L+N
Sbjct 3721 TYTWTTALSMAAAKVIAKWVAVNV--LYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMN 3778
Query 3779 RYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSK 3838
FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+ QSK
Sbjct 3779 SLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSK 3838
Query 3839 MSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSM 3898
++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL +
Sbjct 3839 LTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFAN 3898
Query 3899 QGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-E 3951
AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G + +
Sbjct 3899 PAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGSANQ 3958
Query 3952 VVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLF 4011
LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF
Sbjct 3959 QQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLF 4018
Query 4012 TMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASA 4071
+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TYA
Sbjct 4019 SMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGN 4078
Query 4072 LWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQM 4129
+W+IQ + D+D QL+EI S + WPL++ A R N SA LQNNEL P L+
Sbjct 4079 VWQIQTIQDSDGTNKQLNEI----SDDCNWPLVIIANRHNEVSATVLQNNELMPAKLKTQ 4134
Query 4130 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4189
+G QT T YYNNS G+ V A+LSD LK+ + K DG + EL+PP
Sbjct 4135 VVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPP 4191
Query 4190 CRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAF 4249
C+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF
Sbjct 4192 CKFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAF 4251
Query 4250 AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC 4309
+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+YCR
Sbjct 4252 SVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIYCRA 4311
Query 4310 HIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQ 4369
++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +Q
Sbjct 4312 RVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQ 4369
Query 4370 SADASTFLN 4378
S D + FLN
Sbjct 4370 SKD-TNFLN 4377
Score = 83.6 bits (205), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 51/155 (33%), Positives = 78/155 (50%), Gaps = 2/155 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPN--LNAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
GIF SL + T QV + N++ ++ +
Sbjct 1393 GIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFDLI 1427
Score = 73.2 bits (178), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 77/286 (27%), Positives = 129/286 (45%), Gaps = 36/286 (13%)
Query 729 LLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVC- 784
L MP KA ++ +L+G D L V + L TP ++ V +C
Sbjct 763 LTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSL----TPC-GYSEPPKVADKICI 817
Query 785 VNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-KNVRI 842
V+ + + + DK + + + +R+ + VTF E TV E+ K +++
Sbjct 818 VDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAG--RRVTFKEQPTVNEIASTPKTIKV 875
Query 843 TFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLL---TNMGIDLD 899
+ELD+ + +LN C V+ V+ ++ EF VV +A+ + L P +L + L
Sbjct 876 FYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 900 EWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQG 959
+ + +LFD+AGEE +S++YC+F P EDD EE ++E T+
Sbjct 936 KLEDNSLFLFDEAGEEVLASKLYCAFTAP----EDDDFLEESGVEEDDVEGEETD----- 986
Query 960 LPLEFGASAETVRVEEEEE-----EDWLDD----TTEQSEIEPEPE 996
L ++ E E+EE ED LDD T S++E + E
Sbjct 987 --LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVE 1030
>sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus
OC43 OX=31631 GN=1a PE=1 SV=1
Length=4383
Score = 1879 bits (4868), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1099/2887 (38%), Positives = 1623/2887 (56%), Gaps = 127/2887 (4%)
Query 1545 IKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL 1604
+ + TVD N + V + ++G+ G + DG +VTK K +N++GK FF + +
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSE 1624
Query 1605 RSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLE 1664
+A D+ L Y + L + KW+ G + K A+NNC+++ L LQ L
Sbjct 1625 DLKAVRSSFNFDQKELLAYYNMLVNCFKWQVVVNGKYFTFKQANNNCFVNVSCLMLQSLH 1684
Query 1665 VKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRV 1724
+ F QEA+ R+G A F AL+LA G+ D R+ + + +L A
Sbjct 1685 LTFKIVQWQEAWLEFRSGRPARFVALVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICD 1744
Query 1725 LNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMM 1784
+ CK CG K TG++AVM+ GTLS ++L+ G ++ C CG+ + V+ + F++
Sbjct 1745 FEIACK-CGVKQEQRTGLDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLIC 1802
Query 1785 SAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVF 1844
S PA KL +G AN + G+ GHY H+ +++ D +++ K+++ G ++D
Sbjct 1803 SNTPASVKLPKGVG-SANIFIGD-NVGHYVHVKCEQSYQLYDASNVKKVTDVTGKLSDCL 1860
Query 1845 YKETSYTTTIKPV--SYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLPNAS 1901
Y + + T K V +Y LD V E +P L YY YYT++ I T +
Sbjct 1861 YLK-NLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGV 1919
Query 1902 FDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGA 1960
+ NFKL D LN GF + E +T +P GDVV + Y +++G
Sbjct 1920 YTNFKLIGHTV--CDSLNSKLGFDSSKEFVEYKITEWPTATGDVVLANDDLYVKRYERGC 1977
Query 1961 KLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACES 2020
KP++W ++ K + T+ R L VD N F+VL V+D + +
Sbjct 1978 ITFGKPVIWLSHE---KASLNSLTYFNRPLL----VD-DNKFDVLKVDDVDDSGDSSESG 2029
Query 2021 QQPTSE-EVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVEN 2079
+ T E +++ ++K +V +VI+ K + L D+ ++
Sbjct 2030 AKETKEINIIKLSGVKKPF--------KVEDSVIVNDDTSETKYVKSLSIVDVYDMWLTG 2081
Query 2080 TSITIKKPNELSLALGLKTI---ATHGIAAINSVPWSKI-LAYVKPFLGQAAITTSNCAK 2135
++ N LS A+ + TI G+ + S+P + L +KP A+ +
Sbjct 2082 CKYVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKP-----AVNVVKAVR 2135
Query 2136 RLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYV 2195
FN ++ ++F LLF + + T IA K KL A N
Sbjct 2136 NKTSACFN-FIKWLFVLLFGWIKISADN----KVIYTTEIAS---KLTCKLVALAFKNAF 2187
Query 2196 KSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSYCNGVRELYLNSSNV 2253
+ K+S + A + + + + I F L G P++ + + N+ ++
Sbjct 2188 LTFKWSMVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIAQWIKNTFSL 2247
Query 2254 TTM-------------DFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK-LDLT-IL 2298
T+ +C GS C CL+G D LD+Y A++ +Q +D T +L
Sbjct 2248 VTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVL 2307
Query 2299 GLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSA 2356
+ E +++Y L+T +FY L +Q+ + F+ ++ W ++++ M P
Sbjct 2308 KIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSFRLLVALANMLPAHV 2367
Query 2357 MVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYAN 2416
+R YI ASF ++ + H+ GC+ S C+ CYKRNR+ RV+C+TIV GM R + V AN
Sbjct 2368 FMRFYIIIASFIKLFSLFKHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMAN 2427
Query 2417 GGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNG 2476
GG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V V
Sbjct 2428 GGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGC 2487
Query 2477 ALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASV 2536
++ L++D+ GQ+ Y+ S FV+ NL + K ++V+V + + D++ +A+V
Sbjct 2488 SMRLFYDRDGQRIYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DKANFLNAAV 2545
Query 2537 YYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSE 2596
+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V + L AL+ATAHS
Sbjct 2546 FYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSS 2605
Query 2597 LAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYN 2655
+ +G + VL TF+S AR+ +D+DVDTK + + + + + LE+T +SCNN + TY
Sbjct 2606 IKQGTQIYKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYL 2665
Query 2656 KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNI 2715
K +N+ DLG I +A+H+ VAK VS IW+V + S + +++ A K +
Sbjct 2666 KSDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQFSSDFQHKLKKACCKTGL 2725
Query 2716 PFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYI----VMPVH 2771
+LT V+V+TT SLKGG + S +C + +LVC+I +MP +
Sbjct 2726 KLKLTYNKQMANVSVLTTPFSLKGGAVFSY-------FVYVCFVLSLVCFIGLWCLMPTY 2778
Query 2772 TLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCP 2829
T+ D YK + +GV RD+ D CFANK FD W+ G Y N +CP
Sbjct 2779 TVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACP 2838
Query 2830 VVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSA 2889
+V A+I ++ G V +P VLR LHF+ SA G CYTP I YS+F S
Sbjct 2839 IVVAVIDQDFGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQISYSNFYASG 2897
Query 2890 CVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SIIQFPNTYLEG 2948
CVL++ CT+F A G P PYCY L++ + YS L P RY L + I+FP EG
Sbjct 2898 CVLSSACTMFTMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRFPEVLREG 2957
Query 2949 SVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIF 3008
VRVV T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG D +LI +F
Sbjct 2958 LVRVVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLF 3017
Query 3009 TPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTI 3068
L QPV L ++AS +AG I+A++V YY +K +R FG+Y VV N +++ ++F +
Sbjct 3018 KGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSVVFVNVIVWCVNFMM 3077
Query 3069 LCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLK 3128
L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W +Y+ +
Sbjct 3078 LFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYIAVVVSN 3137
Query 3129 HCHWFFNNYLRK---RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYL 3185
H W F+ Y RK V +G TFEE AL TF++ K+ Y KL++ L +NRYL
Sbjct 3138 HAFWVFS-YCRKLGTSVRSDG----TFEEMALTTFMITKDSYCKLKNS--LSDVAFNRYL 3190
Query 3186 ALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNS-GADVLYQPPQTSITSAVLQSGFR 3244
+LYNKY+Y+SG +DT +YREAAC LAKA++ F+N+ G+DVLYQPP S++++ LQSG
Sbjct 3191 SLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSGIV 3250
Query 3245 KMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNH 3304
KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +LL R ++
Sbjct 3251 KMVNPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVTSS 3310
Query 3305 SFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSG 3364
F V + L V+ + M+ C+L L V N +TPKY F ++PG+TF+VLA YNG P G
Sbjct 3311 DFTVLFDRLSLTVMSYQMRGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKPQG 3370
Query 3365 VYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGP 3424
+ MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G FYGP
Sbjct 3371 AFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFYGP 3430
Query 3425 FVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQ 3484
+ D Q Q D ++N LAWLYAA++N WF+ ++ DFN+ A+ + +
Sbjct 3431 YKDAQVVQLPIQDYIQSVNFLAWLYAAILNNCNWFIQSDKCSVEDFNVWALSNGFSQVKS 3490
Query 3485 DHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVT 3544
D V + L++ TG+++ + AA+K L+NG GR I+GS EDE TP DV +Q +G+
Sbjct 3491 DLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQQLAGIK 3547
Query 3545 FQGKFKKIVKGTHHWMLL-TFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAM 3603
Q K ++ KGT W++ TFL S I+ +W++F +V N F T + + + AM
Sbjct 3548 LQSKRTRLFKGTVCWIMASTFLFS-CIITAFVKWTMFMYVTTNMF-SITFCALCVISLAM 3605
Query 3604 LLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMY 3662
LLVKHKH +L +++ P L T+ Y N +V ++ + WL S+ Y D V+Y
Sbjct 3606 LLVKHKHLYLTMYITPVLFTLLYNNYLVVYKHTFRGYVYAWLSYYVPSVE-YTYTDEVIY 3664
Query 3663 ASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNY 3721
L++ ++ +T R++ D + + +I++ Y G+ L++ I + ++ S+ Y
Sbjct 3665 GMLLLVGMVFVTLRSINHDLFSFIMFVGRLISVFSLWYKGSNLEEEILL--MLASLFGTY 3722
Query 3722 SGVVTTIMFLARAIV-FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
+ M +A+ I +V V L F ++ ++L Y F+GY CY+GLF L+N
Sbjct 3723 TWTTVLSMAVAKVIAKWVAVNV--LYFTDIPQIKIVLLCYLFIGYIISCYWGLFSLMNSL 3780
Query 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+ QSK++
Sbjct 3781 FRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLT 3840
Query 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D + AFEK+ LL VL +
Sbjct 3841 DVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFEKLAQLLIVLFANPA 3900
Query 3901 AVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVV 3953
AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A +G + +
Sbjct 3901 AVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARFSGSANQQQ 3960
Query 3954 LKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTM 4013
LK+L+K+ N+AKS ++RD A+ +KLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M
Sbjct 3961 LKQLEKACNIAKSAYERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSM 4020
Query 4014 LRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALW 4073
+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TYA +W
Sbjct 4021 VRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTYAGNVW 4080
Query 4074 EIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSC 4131
+IQ + D+D QL+EI+ D + WPL++ A R N SA LQNNEL P L+
Sbjct 4081 QIQTIQDSDGTNKQLNEISDDCN----WPLVIIANRYNEVSATVLQNNELMPAKLKIQVV 4136
Query 4132 AAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCR 4191
+G QT T YYNNS G+ V A+LSD LK+ + K DG + EL+PPC+
Sbjct 4137 NSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCK 4193
Query 4192 FVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAV 4251
F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+V
Sbjct 4194 FTVQDAKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSV 4253
Query 4252 DPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHI 4311
DP K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR +
Sbjct 4254 DPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCRARV 4313
Query 4312 DHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSA 4371
+HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC + +QS
Sbjct 4314 EHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCRVCGFWRDGSCSCVS-TDTTVQSK 4371
Query 4372 DASTFLN 4378
D + FLN
Sbjct 4372 D-TNFLN 4377
Score = 83.6 bits (205), Expect = 9e-14, Method: Compositional matrix adjust.
Identities = 51/155 (33%), Positives = 81/155 (52%), Gaps = 2/155 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ + +K
Sbjct 1273 ITPNVCFVKGDIIKVSKLVKAEVVVNPANGHMVHGGGVAKAIAVAAGQQFVKETTNMVKS 1332
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPN--LNAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G G + +G L K L+VVGP+ + LL+ Y++FN+ D ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYVLLERVYKHFNNYDCVVTTLISA 1392
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
GIF SL + T + QV + N++ ++ +
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLI 1427
Score = 68.2 bits (165), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 74/284 (26%), Positives = 126/284 (44%), Gaps = 26/284 (9%)
Query 729 LLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVC- 784
L MP KA ++ +L+G D L V + L TP ++ V +C
Sbjct 763 LTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSL----TPC-GYSEPPKVADKICI 817
Query 785 VNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-KNVRI 842
V+ + + + DK + + + +R+ + VTF E TV E+ K +++
Sbjct 818 VDNVYMAKAGDKYYPVVVDDHVGLLDQAWRVPCAG--RRVTFKEQPTVKEIISMPKIIKV 875
Query 843 TFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLL---TNMGIDLD 899
+ELD + +LN C V+ V+ ++ EF VV +A+ + L P +L + L
Sbjct 876 FYELDNDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQ 935
Query 900 EWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQG 959
+ +LFD+AGEE F+ ++YC+F P E+DD ++E+ E E +
Sbjct 936 KLEDNPLFLFDEAGEEVFAPKLYCAFTAP---EDDDF------LEESDVEEDDVEGEETD 986
Query 960 LPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPV 1003
L + A V E+EE + L+DT + + EE V
Sbjct 987 LTIT-SAGQPCVASEQEESSEVLEDTLDDGPSVETSDSQVEEDV 1029
>sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=1a PE=3 SV=1
Length=4383
Score = 1875 bits (4856), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1091/2892 (38%), Positives = 1622/2892 (56%), Gaps = 137/2892 (5%)
Query 1545 IKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL 1604
+ + TVD N + V + ++G+ G + DG +VTK K +N++GK FF D L
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQF---DNL 1621
Query 1605 RSE---AFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
SE A D+ L Y + L + KW+ G + K A+NNC+++ L LQ
Sbjct 1622 SSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQ 1681
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
L +KF QEA+ R+G A F +L+LA G+ D R+ + + +L A
Sbjct 1682 SLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGA 1741
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
+ CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG+ + V+ + F
Sbjct 1742 ICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPF 1799
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S PA KL +G AN + G+ + GHY H+ +++ D +++ K+++ G ++
Sbjct 1800 LICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLS 1857
Query 1842 DVFYKETSYTTTIKPV--SYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLP 1898
D Y + + T K V +Y LD V E +P L YY YYT++ I T
Sbjct 1858 DCLYLK-NLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKV 1916
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL D LN GF + E VT +P GDVV Y ++
Sbjct 1917 DGVYTNFKLI--GHTVCDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYE 1974
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFEVLAVEDTQGMDNL 2016
+G KP++W ++ + + + +P+ N F+VL V+D ++
Sbjct 1975 RGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFDVLKVDDVDDGGDI 2025
Query 2017 A-CESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
+ ++++P +++ ++K +V +VI+ +K + L D+
Sbjct 2026 SESDAKEPKEINIIKLSGVKKPF--------KVEDSVIVNDDTSEIKYVKSLSIVDVYDM 2077
Query 2076 YVENTSITIKKPNELSLALGLKTI---ATHGIAAINSVPWSKI-LAYVKPFLGQAAITTS 2131
++ ++ N LS A+ + TI G+ + S+P + L +KP
Sbjct 2078 WLTGCRCVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVF-------- 2128
Query 2132 NCAKRLAQRVFN--NYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLD 2189
N K + ++ N++ ++F LLF + + T +A K KL
Sbjct 2129 NVVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---KLTCKLVAL 2181
Query 2190 AGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSYCNGVRELY 2247
A N + K+S + A + + + + I F L G P++ + +
Sbjct 2182 AFKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIVQWI 2241
Query 2248 LNSSNVTTM-------------DFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK-L 2293
N+ ++ T+ +C GS C CL+G D LD+Y A++ +Q +
Sbjct 2242 KNTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFV 2301
Query 2294 DLT-ILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQ 2350
D T +L + E +++Y L+T +FY L +Q+ + + ++ W + ++S+
Sbjct 2302 DYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELLMLSTLHWSVRLLVSLAN 2361
Query 2351 MAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRS 2410
M P +R YI ASF ++ + H+ GC+ S C+ CYKRNR+ RV+C+TIV GM R
Sbjct 2362 MLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRY 2421
Query 2411 FYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDS 2470
+ V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2422 YDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTD 2481
Query 2471 VAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESA 2530
V + L++D+ GQ+TY+ S FV+ NL + K ++V+V + + D++
Sbjct 2482 VKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DKAN 2539
Query 2531 SKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALV 2590
+A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V + L AL+
Sbjct 2540 FLNAAVFYAQSLFRPILMVDKILITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALI 2599
Query 2591 ATAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNN 2649
ATAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE+T +SCNN
Sbjct 2600 ATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCNN 2659
Query 2650 FMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSA 2709
+ TY K +N+ DLG I +A+H+ VAK VS IW+V + LS + +++ A
Sbjct 2660 LVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKA 2719
Query 2710 AKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYI--- 2766
K + LT V+V+TT SLKGG + S +C + +LVC+I
Sbjct 2720 CCKTGLKLELTYNKQMANVSVLTTPFSLKGGAVFSY-------FVYVCFVLSLVCFIGLW 2772
Query 2767 -VMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYK 2823
+MP +T+ D YK + +GV RD+ D CFANK FD W+ G Y
Sbjct 2773 CLMPTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYS 2832
Query 2824 NDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYS 2883
N +CP+V A++ ++ G V +P VLR LHF+ SA G CYTP I YS
Sbjct 2833 NSMACPIVVAVVDQDFGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQISYS 2891
Query 2884 DFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SIIQFP 2942
+F S CVL++ CT+F A G P PYCY L++ + YS L P RY L + I+ P
Sbjct 2892 NFYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRLP 2951
Query 2943 NTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMN 3002
EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG D +
Sbjct 2952 EVLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFD 3011
Query 3003 LIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLF 3062
LI +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N +++
Sbjct 3012 LIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLGFYYLIKLKRAFGDYTSIVFVNVIVW 3071
Query 3063 LMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYV 3122
++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W +Y+
Sbjct 3072 CVNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYI 3131
Query 3123 FCISLKHCHWFFNNYLRK---RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3179
+ H W F+ Y R+ V +G TFEE AL TF++ K+ Y KL++ L
Sbjct 3132 SVVVSNHAFWVFS-YCRQLGTSVRSDG----TFEEMALTTFMITKDSYCKLKNS--LSDV 3184
Query 3180 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNS-GADVLYQPPQTSITSAV 3238
+NRYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F+N+ G+DVLYQPP S++++
Sbjct 3185 AFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSF 3244
Query 3239 LQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLL 3298
LQSG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +LL
Sbjct 3245 LQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLL 3304
Query 3299 IRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACY 3358
R ++ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA Y
Sbjct 3305 CRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAY 3364
Query 3359 NGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLE 3418
NG P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD
Sbjct 3365 NGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFN 3424
Query 3419 GKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYN 3478
G FYGP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+
Sbjct 3425 GDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNG 3484
Query 3479 YEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVR 3538
+ + D V + L++ TG+++ + AA+K L+NG GR I+GS EDE TP DV +
Sbjct 3485 FSQVKSDLV--IDALASMTGVSLETLLAAIKR-LKNGFQGRQIMGSCSFEDELTPSDVYQ 3541
Query 3539 QCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAI 3598
Q +G+ Q K ++VKG W++ + I+ +W++F +V N L T + +
Sbjct 3542 QLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCV 3600
Query 3599 AACAMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLK 3657
+ AMLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y
Sbjct 3601 ISLAMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYT 3659
Query 3658 DCVMYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVIS 3716
D V+Y L++ ++ +T R++ D + + VI++V Y G+ L++ I + ++ S
Sbjct 3660 DEVIYGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLAS 3717
Query 3717 VTSNYSGVVTTIMFLARAIV-FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
+ Y+ M A+ I +V V L F ++ +++ Y F+GY CY+GLF
Sbjct 3718 LFGTYTWTTALSMAAAKVIAKWVAVNV--LYFTDIPQIKIVLVCYLFIGYIISCYWGLFS 3775
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
L+N FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+
Sbjct 3776 LMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQF 3835
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK++DVKC + LL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL
Sbjct 3836 QSKLTDVKCANGGLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVL 3895
Query 3896 LSMQGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
+ AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G
Sbjct 3896 FANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGS 3955
Query 3950 S-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQT 4008
+ + LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QT
Sbjct 3956 ANQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQT 4015
Query 4009 MLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTY 4068
MLF+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TY
Sbjct 4016 MLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 4075
Query 4069 ASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVAL 4126
A +W+IQ + D+D QL EI+ D + WPL++ A R N SA LQNNEL P L
Sbjct 4076 AGNVWQIQTIQDSDGTNKQLHEISDDCN----WPLVIIANRHNEVSATVLQNNELMPAKL 4131
Query 4127 RQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTEL 4186
+ +G QT T YYNNS G+ V A+LSD LK+ + K DG + EL
Sbjct 4132 KTQVVNSGPDQTCNTPTQ--CYYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LEL 4188
Query 4187 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4246
+PPC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS
Sbjct 4189 DPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSL 4248
Query 4247 CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4306
CAF+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+Y
Sbjct 4249 CAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIY 4308
Query 4307 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP 4366
CR ++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC +
Sbjct 4309 CRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDT 4366
Query 4367 LMQSADASTFLN 4378
+QS D + FLN
Sbjct 4367 TVQSKD-TNFLN 4377
Score = 84.3 bits (207), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 51/155 (33%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPN--LNAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
GIF SL + T + QV + N++ ++ +
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLI 1427
Score = 67.0 bits (162), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 54/189 (29%), Positives = 90/189 (48%), Gaps = 17/189 (9%)
Query 822 KGVTFGED-TVWEVQGY-KNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEA 879
+ VTF E TV E+ K +++ +ELD+ + +LN C + V+ ++ EF VV +A
Sbjct 853 RCVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGEFEVDDTVDMEEFYAVVIDA 912
Query 880 VVKTLQPVSDLL---TNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDA 936
+ + L P +L + L + + +LFD+AGEE + ++YC+F P EDD
Sbjct 913 IEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLAPKLYCAFTAP----EDDD 968
Query 937 ECEEEEIDETCEHEYGTEDDYQGLPLEFGASAE-TVRVEEEEEEDWLDDTTEQSEIEPEP 995
EE ++E T+ L ++ E V E+EE + L+DT +
Sbjct 969 FLEESGVEEDDVEGEETD-------LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETS 1021
Query 996 EPTPEEPVN 1004
+ EE V
Sbjct 1022 DSQVEEDVQ 1030
>sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=1a PE=3 SV=1
Length=4383
Score = 1873 bits (4852), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1094/2893 (38%), Positives = 1625/2893 (56%), Gaps = 139/2893 (5%)
Query 1545 IKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTL 1604
+ + TVD N + V + ++G+ G + DG +VTK K +N++GK FF D L
Sbjct 1565 VDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQF---DNL 1621
Query 1605 RSE---AFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
SE A D+ L Y + L + KW+ G + K A+NNC+++ L LQ
Sbjct 1622 SSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQ 1681
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
L +KF QEA+ R+G A F +L+LA G+ D R+ + + +L A
Sbjct 1682 SLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGA 1741
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
+ CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG+ + V+ + F
Sbjct 1742 ICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPF 1799
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S PA KL +G AN + G+ + GHY H+ +++ D +++ K+++ G ++
Sbjct 1800 LICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLS 1857
Query 1842 DVFYKETSYTTTIKPV--SYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLP 1898
D Y + + T K V +Y LD V E +P L YY YYT++ I T
Sbjct 1858 DCLYLK-NLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKV 1916
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL D LN GF + E VT +P GDVV Y ++
Sbjct 1917 DGVYTNFKLI--GHTVCDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYE 1974
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFEVLAVEDTQGMDNL 2016
+G KP++W ++ + + + +P+ N F+VL V+D ++
Sbjct 1975 RGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFDVLKVDDVDDGGDI 2025
Query 2017 A-CESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
+ ++++P +++ ++K +V +VI+ +K + L D+
Sbjct 2026 SESDAKEPKEINIIKLSGVKKPF--------KVEDSVIVNDDTSEIKYVKSLSIVDVYDM 2077
Query 2076 YVENTSITIKKPNELSLALGLKTI---ATHGIAAINSVPWSKI-LAYVKPFLGQAAITTS 2131
++ ++ N LS A+ + TI G+ + S+P + L +KP
Sbjct 2078 WLTGCRCVVRTANALSRAVNVPTIRKFIKFGMTLV-SIPIDLLNLREIKPVF-------- 2128
Query 2132 NCAKRLAQRVFN--NYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLD 2189
N K + ++ N++ ++F LLF + + T +A K KL
Sbjct 2129 NVVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---KLTCKLVAL 2181
Query 2190 AGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSYCNGVRELY 2247
A N + K+S + A + + + + I F L G P++ + +
Sbjct 2182 AFKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIAQWI 2241
Query 2248 LNSSNVTTM-------------DFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK-L 2293
N+ ++ T+ +C GS C CL+G D LD+Y A++ +Q +
Sbjct 2242 KNTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFV 2301
Query 2294 DLT-ILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQ 2350
D T +L + E +++Y L+T +FY L +Q+ + F+ ++ W + ++S+
Sbjct 2302 DYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLAN 2361
Query 2351 MAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRS 2410
M P +R YI ASF ++ + H+ GC+ S C+ CYKRNR+ RV+C+TIV GM R
Sbjct 2362 MLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRY 2421
Query 2411 FYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDS 2470
+ ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V
Sbjct 2422 YDAMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTD 2481
Query 2471 VAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESA 2530
V + L++D+ GQ+TY+ S FV+ NL + K ++V+V + + D++
Sbjct 2482 VKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DKAN 2539
Query 2531 SKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALV 2590
+A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V + L AL+
Sbjct 2540 FLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALI 2599
Query 2591 ATAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNN 2649
ATAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE+T +SCNN
Sbjct 2600 ATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCNN 2659
Query 2650 FMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSA 2709
+ TY K +N+ DLG I +A+H+ VAK VS IW+V + LS + +++ A
Sbjct 2660 LVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKA 2719
Query 2710 AKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYI--- 2766
K + +LT V+V+TT SLKGG + S +C + +LVC+I
Sbjct 2720 CCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSY-------FVYVCFVLSLVCFIGLW 2772
Query 2767 -VMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYK 2823
+MP +T+ D YK + +GV RD+ D CFANK FD W+ G Y
Sbjct 2773 CLMPTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYS 2832
Query 2824 NDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYS 2883
N +CP+V A++ ++ G V +P VLR LHF+ SA G CYTP I YS
Sbjct 2833 NSMACPIVVAVVDQDFGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQISYS 2891
Query 2884 DFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SIIQFP 2942
+F S CVL++ CT+F A G P PYCY L++ + YS L P RY L + I+FP
Sbjct 2892 NFYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRFP 2951
Query 2943 NTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMN 3002
EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG D +
Sbjct 2952 EVLREGLVRIVRTRSMPYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFD 3011
Query 3003 LIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLF 3062
LI +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N +++
Sbjct 3012 LIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVNVIVW 3071
Query 3063 LMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYV 3122
++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W +Y+
Sbjct 3072 CVNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYI 3131
Query 3123 FCISLKHCHWFFNNYLRK---RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3179
+ H W F +Y R+ V +G TFEE AL TF++ K+ Y KL++ L
Sbjct 3132 SVVVSNHAFWVF-SYCRQLGTSVRSDG----TFEEMALTTFMITKDSYCKLKNS--LSDV 3184
Query 3180 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAV 3238
+NRYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F+ N+G+DVLYQPP S++++
Sbjct 3185 AFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSF 3244
Query 3239 LQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLL 3298
LQSG KM P+ KVE C+V VT G TLNGLWL D VYCPRHVIC+A DM NP+Y +LL
Sbjct 3245 LQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDYTNLL 3304
Query 3299 IRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACY 3358
R ++ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA Y
Sbjct 3305 CRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAY 3364
Query 3359 NGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLE 3418
NG P G + MR ++TIKGSFL GSCGSV + I DCV F YMH +EL TG H GTD
Sbjct 3365 NGKPQGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMGDCVKFVYMHQLELSTGCHTGTDFN 3424
Query 3419 GKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYN 3478
G FYGP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+
Sbjct 3425 GDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNG 3484
Query 3479 YEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVR 3538
+ + D V + L++ TG+++ + AA+K L+NG GR I+GS EDE TP DV +
Sbjct 3485 FSQVKSDLV--IDALASMTGVSLETLLAAIKH-LKNGFQGRQIMGSCSFEDELTPSDVYQ 3541
Query 3539 QCSGVTFQGKFKKIVKGTHHWMLL-TFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA 3597
Q +G+ Q K ++VKG W++ TFL S I+ +W++F +V N L T +
Sbjct 3542 QLAGIKLQSKRTRLVKGIVCWIMASTFLFS-CIITAFVKWTMFMYVTTN-MLSITFCALC 3599
Query 3598 IAACAMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRL 3656
+ + MLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y
Sbjct 3600 VISLTMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTY 3658
Query 3657 KDCVMYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVI 3715
D V+Y L++ ++ +T R++ + + VI++V Y G+ L++ I + ++
Sbjct 3659 TDEVIYGMLLLIGMVFVTLRSINQYLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLA 3716
Query 3716 SVTSNYSGVVTTIMFLARAIV-FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLF 3774
S+ Y+ M A+ I +V V L F ++ +++ Y F+GY CY+GLF
Sbjct 3717 SLFGTYTWTTALSMAAAKVIAKWVAVNV--LYFTDIPQIKIVLVCYLFIGYIISCYWGLF 3774
Query 3775 CLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVAT 3834
L+N FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+
Sbjct 3775 SLMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQ 3834
Query 3835 VQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSV 3894
QSK++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL V
Sbjct 3835 FQSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIV 3894
Query 3895 LLSMQGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANG 3948
L + AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G
Sbjct 3895 LFANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSG 3954
Query 3949 DS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQ 4007
+ + LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+Q
Sbjct 3955 SANQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQ 4014
Query 4008 TMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFT 4067
TMLF+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D T
Sbjct 4015 TMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVT 4074
Query 4068 YASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVA 4125
YA +W+IQ + D+D QL EI+ D + WPL++ A R N SA LQNNEL P
Sbjct 4075 YAGNVWQIQTIQDSDGTNKQLHEISDDCN----WPLVIIANRHNEVSATALQNNELMPAK 4130
Query 4126 LRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTE 4185
L+ +G QT T YYNNS G+ V A+LSD LK+ + K DG + E
Sbjct 4131 LKTQVVNSGPDQTCNTPTQ--CYYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LE 4187
Query 4186 LEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLS 4245
L+PPC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS
Sbjct 4188 LDPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILS 4247
Query 4246 FCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCL 4305
CAF+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+
Sbjct 4248 LCAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCI 4307
Query 4306 YCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLRE 4365
YCR ++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC +
Sbjct 4308 YCRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TD 4365
Query 4366 PLMQSADASTFLN 4378
+QS D + FLN
Sbjct 4366 TTVQSKD-TNFLN 4377
Score = 84.7 bits (208), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 51/155 (33%), Positives = 79/155 (51%), Gaps = 2/155 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1273 ITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKS 1332
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPN--LNAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+SA
Sbjct 1333 KGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISA 1392
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
GIF SL + T + QV + N++ ++ +
Sbjct 1393 GIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLI 1427
Score = 70.1 bits (170), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 57/197 (29%), Positives = 96/197 (49%), Gaps = 18/197 (9%)
Query 822 KGVTFGED-TVWEVQGY-KNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEA 879
+ VTF E TV E+ K +++ +ELD+ + +LN C V+ V+ ++ EF VV +A
Sbjct 853 RCVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDA 912
Query 880 VVKTLQPVSDLL---TNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDA 936
+ + L P +L + L + + +LFD+AGEE + ++YC+F P EDD
Sbjct 913 IEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLAPKLYCAFTAP----EDDD 968
Query 937 ECEEEEIDETCEHEYGTEDDYQGLPLEFGASAE-TVRVEEEEEEDWLDDTTEQSEIEPEP 995
EE ++E T+ L ++ E V E+EE + L+DT +
Sbjct 969 FLEESGVEEDDVEGEETD-------LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETS 1021
Query 996 EPTPEEPVNQFTGYLKL 1012
+ EE V Q + ++ L
Sbjct 1022 DSQVEEDV-QMSDFVDL 1037
>sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus
(strain 2) OX=76344 GN=1a PE=3 SV=1
Length=4416
Score = 1860 bits (4818), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1098/2915 (38%), Positives = 1607/2915 (55%), Gaps = 143/2915 (5%)
Query 1526 EVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIK 1585
+V S+ ++++LL+ + V TVD N + V +G+ G + DG +VTK++
Sbjct 1543 KVASVSQIRALLA----NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR 1598
Query 1586 PHVNHEGKTFF----VLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGL 1641
H+GK FF + +D ++AF + DE L +Y + L K W G
Sbjct 1599 CSAIHKGKVFFQYSGLSAADLVAVTDAFGF----DEPQLLKYYNMLGMCK-WPVVVCGNY 1653
Query 1642 TSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGE 1701
+ K ++NNCY++ L LQ L +KF+ QEA+ R+G F +L+LA + E
Sbjct 1654 FAFKQSNNNCYINVACLMLQHLSLKFHKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNE 1713
Query 1702 LGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVS 1761
D + M +L+ A+L A VCK CG K GV+AVM+ GTL +L G +
Sbjct 1714 PSDSTDFMRVVLREADLSGATCDFEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLAKGYT 1772
Query 1762 IPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKET 1821
I C CG + Q F++ S P KL + AN +TG GHYTH+ K
Sbjct 1773 IACTCGNKLV-HCTQLNVPFLICSNKPEGKKLPDDV-VAANIFTGG-SLGHYTHVKCKPK 1829
Query 1822 LYRIDGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKD 1880
D +++K+SE KG TD Y K T + K ++ LD V E P L YY +
Sbjct 1830 YQLYDACNVSKVSEAKGNFTDCLYLKNLKQTFSSKLTTFYLDDVKCVEYNPDLSQYYCES 1889
Query 1881 NAYYTEQPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFP 1938
YYT+ I T + NFKL A+ N GF E +T +P
Sbjct 1890 GKYYTKPIIKAQFRTFEKVEGVYTNFKLV--GHSIAEKFNAKLGFDCNSPFTEYKITEWP 1947
Query 1939 DLNGDVVAIDYRHYSASFKKGAKLLHKPIVW--HINQATTKTTF--KPNTWCLRCLWSTK 1994
GDVV Y + + G KP++W H + T+ +P+ C ++
Sbjct 1948 TATGDVVLASDDLYVSRYSGGCVTFGKPVIWLGHEEASLKSLTYFNRPSVVCEN-KFNVL 2006
Query 1995 PVDTSNSFEV----LAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE---------- 2040
PVD S + AV T + A ++V + ++ +V+
Sbjct 2007 PVDVSEPTDKGPVPAAVLVTGALSGAATAPGTAKEQKVCASDSVVDQVVSGFLSDLSGAT 2066
Query 2041 CDVKTTEVVG---------NVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELS 2091
DVK ++ G +V++ KV + L D+ ++ + NELS
Sbjct 2067 VDVKEVKLNGVKKPIKVEDSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWMANELS 2126
Query 2092 LALGLKTIATHGIAAINSVPW--SKILAYVKPFLGQAAITTSNCAKRLAQRVFNNY--MP 2147
+ T+ + V W +KI+ K L + K + +V Y +
Sbjct 2127 RLVNSPTVREY-------VKWGMTKIVIPAKLVLLRDEKQEFVAPKVVKAKVIACYSAVK 2179
Query 2148 YVFTLLFQLCTF--------TKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPK 2199
+ F F F T S++ +L KN++++ + G V +
Sbjct 2180 WFFLYCFSWIKFNTDNKVIYTTEVASKLTFNLCCLAFKNALQTFNWNVVSRGFFLVAT-- 2237
Query 2200 FSKLFTIAMWLLLLSICLGSLICVTAAF---------GVLLSNFGAPSYCNGVRELYLNS 2250
+F + L ++ L F + + FG + C +LY S
Sbjct 2238 ---VFLLWFNFLYANVILSDFYLPNIGFFPTFVGQIVAWVKTTFGIFTLC----DLYQVS 2290
Query 2251 SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQ-VTISSYKLD-LTILGLAAEWVLAY 2308
FC GS C +C SG D LD+Y A+ +Q V D +++ L E V+ Y
Sbjct 2291 DVGYRSSFCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRVSFDYISLFKLVVELVIGY 2350
Query 2309 MLFTKFFY-LLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFA 2365
L+T FY L GL MQ+ + F+ + W F + + M P ++R YI
Sbjct 2351 SLYTVCFYPLFGLIG-MQLLTTWLPEFFMLETMHWSARFFVFVANMLPAFTLLRFYIVVT 2409
Query 2366 SFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTH 2425
+ Y I+ H+M GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H
Sbjct 2410 AMYKIFCLCRHVMYGCSRPGCLFCYKRNRSVRVKCSTVVGGTLRYYDVMANGGTGFCAKH 2469
Query 2426 NWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKA 2485
WNCLNC F G+TFI+ E A DLS + KRP+NPTD + Y+V V ++ L++++
Sbjct 2470 QWNCLNCSAFGPGNTFITHEAAADLSKELKRPVNPTDSAYYLVTEVKQVGCSMRLFYERD 2529
Query 2486 GQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQP 2545
GQ+ Y+ S FV+++ L + KG +V+V + ++ D++ +A+V+Y+Q + +P
Sbjct 2530 GQRVYDDVSASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRP 2587
Query 2546 ILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDG 2605
+LL+++ L++ VS MFD YVD+ V + L + V AH+ L +GV L+
Sbjct 2588 MLLVEKKLITTANTGLSVSQTMFDLYVDSLLGVLDVDRKSLTSFVNAAHNSLKEGVQLEQ 2647
Query 2606 VLSTFVSAARQG-VVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRD 2664
V+ TF+ AR+ +D+DV+TK + + + + ++ ++ T +SCNN + TY K + + D
Sbjct 2648 VMDTFIGCARRKCAIDSDVETKSITKSIMSAVNAGVDFTDESCNNLVPTYVKSDTIVAAD 2707
Query 2665 LGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATT 2724
LG I NA+H+ A VAK+ NV+ IW+V + LS L+ ++R A K + +LT
Sbjct 2708 LGVLIQNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQ 2767
Query 2725 RQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEII 2784
V ++TT SLKGG + S + + L+C + V + +MP + + D
Sbjct 2768 EANVPILTTPFSLKGGAVFSKVLQWLFVVNLICFI---VLWALMPTYAVHKSDMQLPLYA 2824
Query 2785 GYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREIGFI 2842
+K I +GV RD+ TD CFANK FD W+ G Y+N ++CPVV A+I ++IG+
Sbjct 2825 SFKVIDNGVLRDVTVTDACFANKFIQFDQWYESTFGLVYYRNSRACPVVVAVIDQDIGYT 2884
Query 2843 VPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDA 2902
+ +P VLR LHF+ F+ CYTP I Y +F S CVL++ CT+ A
Sbjct 2885 LFNVPTKVLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHA 2943
Query 2903 MGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYC 2961
G P PYCY ++ + Y L P RY L + + I+FP EG VR+V T YC
Sbjct 2944 DGTPHPYCYTEGIMHNASLYDSLAPHVRYNLANSNGYIRFPEVVSEGIVRIVRTRSMTYC 3003
Query 2962 RHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVS 3021
R G CE +E G+C + + WVLNN +YRA+ G FCG +A +LI + LV+P+ ++
Sbjct 3004 RVGLCEDAEEGVCFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALT 3063
Query 3022 ASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGV 3081
AS VAG I+AI+V A YY +K +R FG+Y VV N +++ ++F +L + Y L +
Sbjct 3064 ASSVAGAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCL 3123
Query 3082 YSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRK- 3140
Y+ FY Y T YF +++S + HLQW M+ I+P W IYV + H W F+ Y RK
Sbjct 3124 YACFYFYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFS-YCRKL 3182
Query 3141 --RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGAL 3198
V +G TFEE +L TF++ KE Y KL++ + +NRYL+LYNKY+YFSG +
Sbjct 3183 GTEVRSDG----TFEEMSLTTFMITKESYCKLKNS--VSDVAFNRYLSLYNKYRYFSGKM 3236
Query 3199 DTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3257
DT +YREAAC LAKA+ F+ N+G DVLYQPP S+T++ LQSG KM FP+ KVE C+
Sbjct 3237 DTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVFPTSKVEPCV 3296
Query 3258 VQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRV 3317
V VT G TLNGLWLDD VYCPRHVIC++ DM +P+Y +LL R + F V +G + L V
Sbjct 3297 VSVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYSNLLCRVISSDFCVMSGRMSLTV 3356
Query 3318 IGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIK 3377
+ + MQ LL L V NP TPKY F ++PG+TF+VLA YNG G + MR ++TIK
Sbjct 3357 MSYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGKSQGAFHVTMRSSYTIK 3416
Query 3378 GSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTD 3437
GSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q Q D
Sbjct 3417 GSFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQD 3476
Query 3438 TTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQT 3497
T T+NV+AWLYAA++N WF+ + +L +FN+ AM + + D V L L++ T
Sbjct 3477 YTQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMT 3534
Query 3498 GIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTH 3557
G+ V + AA+K L +G G+ ILGS +LEDE TP DV +Q +GV Q K ++VKGT
Sbjct 3535 GVTVEQILAAIKRLY-SGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVVKGTC 3593
Query 3558 HWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFL 3617
W+L + L I+ +W++F +V + L TL + + AMLLVKHKH +L +F+
Sbjct 3594 CWILASTLLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLVKHKHLYLTMFI 3652
Query 3618 LPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASA-LVLLILMTAR 3675
+P L T+ Y N +V S+ WL ++ Y D V+Y LV ++ +T R
Sbjct 3653 MPVLCTLFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLYGVVLLVAMVFVTMR 3711
Query 3676 TVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAI 3735
++ D ++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA A
Sbjct 3712 SINHDVFSVMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAK 3767
Query 3736 VFVCVEYYPLLFITG-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVST 3794
V +L+ T ++ ++L Y +GY CCCY+G+ LLN FR+ LGVY+Y +S
Sbjct 3768 VIAKWLAVNVLYFTDVPQVKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISV 3827
Query 3795 QEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQ 3854
QE RYMN+ GL PP++S +A LN KLLGIGG P I+V+ +QS+++DVKC +VVLL+ LQ
Sbjct 3828 QELRYMNANGLRPPRNSFEALVLNFKLLGIGGVPVIEVSQIQSRLTDVKCVNVVLLNCLQ 3887
Query 3855 QLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLC 3908
L + SSSKLW C LHN+IL D + AF+K+ LL VL + AVD I +
Sbjct 3888 HLHIASSSKLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVS 3947
Query 3909 EEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSE 3967
++ + + LQA+ SEF ++ S+ Y A++ ++A A+G + + +K+L+K+ N+AKS
Sbjct 3948 DDYVRDSTVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSA 4007
Query 3968 FDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIIN 4027
++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++
Sbjct 4008 YERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKLDNQALNSILD 4067
Query 4028 NARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQ 4087
NA GCVPLN IP T+ L ++VPD + D TYA +W IQ + DAD + Q
Sbjct 4068 NAVKGCVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQ 4127
Query 4088 LSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNA 4145
L+EI++ N+ WPL++ A R N S+V LQNNEL P LR +G+ T
Sbjct 4128 LNEIDV----NITWPLVIAANRHNEVSSVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ- 4182
Query 4146 LAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL 4205
YYN + G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYL
Sbjct 4183 -CYYNTTGMGKIVYAILSDCDGLKYTKIVKEDGN-CVVLELDPPCKFSVQDVKGLKIKYL 4240
Query 4206 YFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGG 4265
YF+KG N L RG V+G+L++TVRLQAG ATE +NS + S CAF+VDP K Y DY+ GG
Sbjct 4241 YFVKGCNTLARGWVVGTLSSTVRLQAGTATEYASNSAIRSLCAFSVDPKKTYLDYIQQGG 4300
Query 4266 QPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGK 4325
P+TNCVKMLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK
Sbjct 4301 APVTNCVKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGK 4360
Query 4326 YVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSC 4360
+VQ+P DPV + L + VC VCG W+ CSC
Sbjct 4361 FVQVPLG-IKDPVSYVLTHDVCQVCGFWRDGSCSC 4394
Score = 77.0 bits (188), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 113/464 (24%), Positives = 193/464 (42%), Gaps = 57/464 (12%)
Query 569 ILDGISEQSLRLVDA-------MVYTSDLLTNSVIIMAYVTGGLVQQTSQWLSNLLGTT- 620
+LDG+ +S L+ + MV S +T+ + MA + V+ ++++ + G
Sbjct 576 LLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMALLFMHDVKVATKYVKKVTGKLA 635
Query 621 -------VEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
V +R I EW + + W + L+ G+F + G I SD + +
Sbjct 636 VRFKALGVAVVRKITEWFDLAVDTAAS--AAGWLCYQ-LVNGLFAVANGGITFLSD-VPE 691
Query 674 CVKCFIDVVNKALEMCIDQVTIA---GAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLL 730
VK F+D ++ ID ++++ G + V +A K +Y + K +
Sbjct 692 LVKNFVDKFKVFFKVLIDSMSVSVLSGLTVVKTASNRVCLAGCK-VYE--VVQKRLSAYV 748
Query 731 MPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGEL--EALETPVDSFTNGAIVGTPVCVNGL 788
MP+ E T L G+ V+ + V + L + P SF +V + L
Sbjct 749 MPVGC-NEATCLVGEIEPAVVEDDVVDVVKAPLTYQGCCKPPTSFEKICVV------DKL 801
Query 789 MLLEIKDKEQYCAL---SPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGYKNVRITF 844
+ + D+ + + G+L F G K V F + V E+ + ++I F
Sbjct 802 YMAKCGDQFYPVVVDNDTIGVLDQCWRFPCAG----KKVEFNDKPKVKEIPSTRKIKINF 857
Query 845 ELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD---LLTNMGIDLDEW 901
LD D VL++ CS + V+ + E VV +AV TL P + + T + L+
Sbjct 858 ALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEHDVIGTKVCALLNRL 917
Query 902 SVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLP 961
+ YLFD+ GEE + +MYCSF PD+E +C ++ + E++ DD L
Sbjct 918 AEDYVYLFDEGGEEVIAPKMYCSFSAPDDE-----DCVAADVVDADENQGDDADDSAALV 972
Query 962 L----EFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEE 1001
E G + V V E + D E +IE +P E
Sbjct 973 TDTQEEDGVAKGQVGVAESDAR---LDQVEAFDIEKVEDPILNE 1013
Score = 57.8 bits (138), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 52/149 (35%), Positives = 76/149 (51%), Gaps = 2/149 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV D++K + VIVN AN + HG GVAGA+ KA + KE+ D +K
Sbjct 1267 ITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKSFIKETADMVKN 1326
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G VG +G NL K L++VGP+ + + L+ AY++ N D ++ L+SA
Sbjct 1327 QGVCQVGECYESTGGNLCKTVLNIVGPDARGHGKQCYSFLERAYQHINKCDDVVTTLISA 1386
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDK 1158
GIF SL + V V + N+K
Sbjct 1387 GIFSVPTDVSLTYLIGVVTKNVILVSNNK 1415
>sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronavirus
(strain A59) OX=11142 GN=1a PE=1 SV=1
Length=4468
Score = 1850 bits (4792), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1100/2910 (38%), Positives = 1611/2910 (55%), Gaps = 140/2910 (5%)
Query 1529 SLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHV 1588
S+ ++++LL+ + V TVD N + V +G+ G + DG +VTK++
Sbjct 1599 SVSQIRALLA----NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSA 1654
Query 1589 NHEGKTFF----VLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSI 1644
++GK FF + +D +AF + DE L +Y + L K W G +
Sbjct 1655 IYKGKVFFQYSDLSEADLVAVKDAFGF----DEPQLLKYYTMLGMCK-WPVVVCGNYFAF 1709
Query 1645 KWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGD 1704
K ++NNCY++ L LQ L +KF QEA+ R+G F +L+LA + E D
Sbjct 1710 KQSNNNCYINVACLMLQHLSLKFPKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSD 1769
Query 1705 VRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPC 1764
+ M +L+ A+L A L VCK CG K GV+AVM+ GTL +L G +I C
Sbjct 1770 SIDFMRVVLREADLSGATCNLEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLVRGYNIAC 1828
Query 1765 VCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYR 1824
CG + Q F++ S P KL + AN +TG GHYTH+ K
Sbjct 1829 TCGSKLV-HCTQFNVPFLICSNTPEGRKLPDDV-VAANIFTGG-SVGHYTHVKCKPKYQL 1885
Query 1825 IDGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAY 1883
D ++ K+SE KG TD Y K T + ++ LD V E +P L YY + Y
Sbjct 1886 YDACNVNKVSEAKGNFTDCLYLKNLKQTFSSVLTTFYLDDVKCVEYKPDLSQYYCESGKY 1945
Query 1884 YTEQPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLN 1941
YT+ I T + + NFKL A+ LN GF E +T +P
Sbjct 1946 YTKPIIKAQFRTFEKVDGVYTNFKLV--GHSIAEKLNAKLGFDCNSPFVEYKITEWPTAT 2003
Query 1942 GDVVAIDYRHYSASFKKGAKLLHKPIVW--HINQATTKTTF--KPNTWCLRCLWSTKPVD 1997
GDVV Y + + G KP+VW H + T+ +P+ C ++ PVD
Sbjct 2004 GDVVLASDDLYVSRYSSGCITFGKPVVWLGHEEASLKSLTYFNRPSVVCEN-KFNVLPVD 2062
Query 1998 TSNSFE------VLAVEDTQGMD----------NLACES---QQPTSEEVVENPTIQ--- 2035
S + + V G D AC S + EV + P++
Sbjct 2063 VSEPTDKGPVPAAVLVTGVPGADASAGAGIAKEQKACASASVEDQVVTEVRQEPSVSAAD 2122
Query 2036 -KEVIECDVKT-TEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLA 2093
KEV VK +V G+V++ KV + L D+ ++ + NELS
Sbjct 2123 VKEVKLNGVKKPVKVEGSVVVNDPTSETKVVKSLSIVDVYDMFLTGCKYVVWTANELSRL 2182
Query 2094 LGLKTIATHGIAAINSVPWS--KILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFT 2151
+ T+ + V W KI+ K L + K + + Y +
Sbjct 2183 VNSPTVREY-------VKWGMGKIVTPAKLLLLRDEKQEFVAPKVVKAKAIACYCAVKWF 2235
Query 2152 LLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFS----KLFTIA 2207
LL+ +T++++ + T +A K KLC A N +++ +S F +A
Sbjct 2236 LLYCFSWIKFNTDNKVIYT--TEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVA 2290
Query 2208 MWLLLLSICLGSLICVTAAFGVLLSNFGA-PSYCNGVRELYLNSSNVTTM---------- 2256
LL L + + ++ + L N G P++ + + + V+T+
Sbjct 2291 TVFLLWFNFLYANVILSDFY---LPNIGPLPTFVGQIVAWFKTTFGVSTICDFYQVTDLG 2347
Query 2257 ---DFCEGSFPCSICLSGLDSLDSYPALETIQ-VTISSYKLD-LTILGLAAEWVLAYMLF 2311
FC GS C +C SG D LD+Y A+ +Q V D +++ L E V+ Y L+
Sbjct 2348 YRSSFCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRLSFDYISLFKLVVELVIGYSLY 2407
Query 2312 TKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFASFYY 2369
T FY L + MQ+ + F+ + W + + M P ++R YI + Y
Sbjct 2408 TVCFYPLFVLIGMQLLTTWLPEFFMLETMHWSARLFVFVANMLPAFTLLRFYIVVTAMYK 2467
Query 2370 IWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNC 2429
++ H+M GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNC
Sbjct 2468 VYCLCRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNC 2527
Query 2430 LNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKT 2489
LNC+++ G+TFI+ E A DLS + KRP+NPTD + Y V V ++ L++++ GQ+
Sbjct 2528 LNCNSWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVTEVKQVGCSMRLFYERDGQRV 2587
Query 2490 YERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLL 2549
Y+ S FV+++ L + KG +V+V + ++ D++ A+V+Y+Q + +P+L++
Sbjct 2588 YDDVNASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLGAAVFYAQSLYRPMLMV 2645
Query 2550 DQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLST 2609
++ L++ VS MFD YVD+ V + L + V AH+ L +GV L+ V+ T
Sbjct 2646 EKKLITTANTGLSVSRTMFDLYVDSLLNVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDT 2705
Query 2610 FVSAARQG-VVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGAC 2668
F+ AR+ +D+DV+TK + + + + ++ ++ T +SCNN + TY K + + DLG
Sbjct 2706 FIGCARRKCAIDSDVETKSITKSVMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGVL 2765
Query 2669 IDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVV 2728
I NA+H+ A VAK+ NV+ IW+V + LS L+ ++R A K + +LT V
Sbjct 2766 IQNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEANV 2825
Query 2729 NVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKA 2788
++TT SLKGG + S + + A L+C + V + +MP + + D +K
Sbjct 2826 PILTTPFSLKGGAVFSRMLQWLFVANLICFI---VLWALMPTYAVHKSDMQLPLYASFKV 2882
Query 2789 IQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREIGFIVPGL 2846
I +GV RD+ TD CFANK FD W+ G Y+N K+CPVV A+I ++IG + +
Sbjct 2883 IDNGVLRDVSVTDACFANKFNQFDQWYESTFGLAYYRNSKACPVVVAVIDQDIGHTLFNV 2942
Query 2847 PGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKP 2906
P TVLR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P
Sbjct 2943 PTTVLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTP 3001
Query 2907 VPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRHGT 2965
PYCY ++ + YS L P RY L + I+FP EG VRVV T YCR G
Sbjct 3002 HPYCYTGGVMHNASLYSSLAPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGL 3061
Query 2966 CERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVV 3025
CE +E GIC + + WVLNN +YRA+ G FCG +A +LI + LV+P+ ++AS V
Sbjct 3062 CEEAEEGICFNFNRSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASSV 3121
Query 3026 AGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVF 3085
AG I+AI+V A YY +K +R FG+Y VV N +++ ++F +L + Y L +Y+ F
Sbjct 3122 AGAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACF 3181
Query 3086 YLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRK---RV 3142
Y Y T YF +++S + HLQW M+ I+P W IYV + H W F+ Y RK V
Sbjct 3182 YFYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFS-YCRKIGTEV 3240
Query 3143 MFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTS 3202
+G TFEE AL TF++ KE Y KL++ + +NRYL+LYNKY+YFSG +DT +
Sbjct 3241 RSDG----TFEEMALTTFMITKESYCKLKNS--VSDVAFNRYLSLYNKYRYFSGKMDTAA 3294
Query 3203 YREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVT 3261
YREAAC LAKA+ F+ N+G DVLYQPP S+T++ LQSG KM P+ KVE C+V VT
Sbjct 3295 YREAACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCIVSVT 3354
Query 3262 CGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHS 3321
G TLNGLWLDD VYCPRHVIC++ DM +P+Y +LL R ++ F V +G + L V+ +
Sbjct 3355 YGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSGRMSLTVMSYQ 3414
Query 3322 MQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFL 3381
MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + +R +HTIKGSFL
Sbjct 3415 MQGCQLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVTLRSSHTIKGSFL 3474
Query 3382 NGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTIT 3441
GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q Q D T T
Sbjct 3475 CGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQT 3534
Query 3442 LNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAV 3501
+NV+AWLYAA+ N WF+ + +L +FN+ AM + + D V L L++ TG+ V
Sbjct 3535 VNVVAWLYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTV 3592
Query 3502 LDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWML 3561
+ AA+K L +G G+ ILGS +LEDE TP DV +Q +GV Q K +++KGT W+L
Sbjct 3593 EQVLAAIKR-LHSGFQGKQILGSCVLEDE-TPSDVYQQLAGVKLQSKRTRVIKGTCCWIL 3650
Query 3562 LTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSL 3621
+ I+ +W++F +V + L TL + + AMLL+KHKH +L ++++P L
Sbjct 3651 ASTFLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLIKHKHLYLTMYIMPVL 3709
Query 3622 ATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASA-LVLLILMTARTVYDD 3680
T +V S+ WL ++ Y D V+Y LV ++ +T R++ D
Sbjct 3710 CTFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLYGVVLLVAMVFVTMRSINHD 3768
Query 3681 AARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCV 3740
++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA A V
Sbjct 3769 VFSIMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKW 3824
Query 3741 EYYPLLFITG-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRY 3799
+L+ T ++ ++L Y +GY CCCY+G+ LLN FR+ LGVY+Y +S QE RY
Sbjct 3825 LAVNVLYFTDVPQIKLVLLSYLCIGYVCCCYWGILSLLNSIFRMPLGVYNYKISVQELRY 3884
Query 3800 MNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVE 3859
MN+ GL PP++S +A LN KLLGIGG P I+V+ +QS+++DVKC +VVLL+ LQ L +
Sbjct 3885 MNANGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIA 3944
Query 3860 SSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLCEEMLD 3913
S+SKLW C LHN+IL D + AF+K+ LL VL + AVD I + ++ +
Sbjct 3945 SNSKLWQYCSTLHNEILATSDLSMAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVR 4004
Query 3914 NRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDA 3972
+ LQA+ SEF ++ S+ Y A++ ++A A+G + + +K+L+K+ N+AKS ++RD
Sbjct 4005 DNTVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDR 4064
Query 3973 AMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDG 4032
A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA G
Sbjct 4065 AVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKG 4124
Query 4033 CVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEIN 4092
CVPLN IP T+ L ++VPD + D TYA +W IQ + DAD + QL+EI+
Sbjct 4125 CVPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEID 4184
Query 4093 MDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN 4150
++++ WPL++ A R N S V LQNNEL P LR +G+ T YYN
Sbjct 4185 VNST----WPLVIAANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ--CYYN 4238
Query 4151 NSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKG 4210
+ G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG
Sbjct 4239 TTGTGKIVYAILSDCDGLKYTKIVKEDGN-CVVLELDPPCKFSVQDVKGLKIKYLYFVKG 4297
Query 4211 LNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITN 4270
N L RG V+G+L++TVRLQAG ATE +NS +LS CAF+VDP K Y DY+ GG P+TN
Sbjct 4298 CNTLARGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIKQGGVPVTN 4357
Query 4271 CVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIP 4330
CVKMLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4358 CVKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVP 4417
Query 4331 TTCANDPVGFTLRNTVCTVCGMWKGYGCSC 4360
DPV + L + VC VCG W+ CSC
Sbjct 4418 LG-IKDPVSYVLTHDVCQVCGFWRDGSCSC 4446
Score = 82.8 bits (203), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 52/149 (35%), Positives = 77/149 (52%), Gaps = 2/149 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV D++K + N VIVN AN + HG GVAGA+ + A KE+ D +K
Sbjct 1320 ITPNVCFVKGDVIKVVRLVNAEVIVNPANGRMAHGAGVAGAIAEKAGSAFIKETSDMVKA 1379
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G VG +G L KK L++VGP+ + + LL+ AY++ N D ++ L+SA
Sbjct 1380 QGVCQVGECYESAGGKLCKKVLNIVGPDARGHGKQCYSLLERAYQHINKCDNVVTTLISA 1439
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDK 1158
GIF SL + V V + N++
Sbjct 1440 GIFSVPTDVSLTYLLGVVTKNVILVSNNQ 1468
Score = 79.0 bits (193), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 111/455 (24%), Positives = 194/455 (43%), Gaps = 66/455 (15%)
Query 569 ILDGISEQSLRLVDA-------MVYTSDLLTNSVIIMAYVTGGLVQQTSQWLSNLLGTT- 620
+LDG+ +S L+ + MV S +T+ + MA + V+ ++++ + G
Sbjct 576 LLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMALLFMHDVKVATKYVKKVTGKLA 635
Query 621 -------VEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
V +R I EW + L+ + W + L+ G+F + G I + + +
Sbjct 636 VRFKALGVAVVRKITEWFD--LAVDIAASAAGWLCYQ-LVNGLFAVANGVITFVQE-VPE 691
Query 674 CVKCFIDVVNKALEMCIDQVTIA---GAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLL 730
VK F+D ++ ID ++++ G + V +A SK +Y + K +
Sbjct 692 LVKNFVDKFKAFFKVLIDSMSVSILSGLTVVKTASNRVCLAGSK-VYE--VVQKSLSAYV 748
Query 731 MPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGEL--EALETPVDSFTNGAIVGTPVCVNGL 788
MP+ E T L G+ V + V + L + P SF IV + L
Sbjct 749 MPVGC-SEATCLVGEIEPAVFEDDVVDVVKAPLTYQGCCKPPTSFEKICIV------DKL 801
Query 789 MLLEIKDKEQYCAL---SPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGYKNVRITF 844
+ + D+ + + G+L F G K V F + V ++ + ++ITF
Sbjct 802 YMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAG----KKVEFNDKPKVRKIPSTRKIKITF 857
Query 845 ELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD---LLTNMGIDLDEW 901
LD D VL++ CS + V+ + E VV +AV TL P + + T + LD
Sbjct 858 ALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEHDVIGTKVCALLDRL 917
Query 902 SVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLP 961
+ YLFD+ G+E + RMYCSF PD+E +C ++ + E++ +DD
Sbjct 918 AGDYVYLFDEGGDEVIAPRMYCSFSAPDDE-----DCVAADVVDADENQ---DDD----- 964
Query 962 LEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPE 996
A V V + +EE D + ++E + E
Sbjct 965 ----AEDSAVLVADTQEE----DGVAKGQVEADSE 991
>sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronavirus
(strain JHM) OX=11144 GN=1a PE=1 SV=1
Length=4474
Score = 1843 bits (4774), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1088/2915 (37%), Positives = 1598/2915 (55%), Gaps = 143/2915 (5%)
Query 1529 SLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHV 1588
S+ ++++LL+ + V TVD N + V +G+ G + DG +VTK++
Sbjct 1598 SVSQIRALLA----NKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVRCSA 1653
Query 1589 NHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWAD 1648
H+GK FF A + DE L +Y S L K W G + K ++
Sbjct 1654 IHKGKVFFQYSGLSAADLAAVKDAFGFDEPQLLQYYSMLGMCK-WPVVVCGNYFAFKQSN 1712
Query 1649 NNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRET 1708
NNCY++ L LQ L +KF + R+G F +L+LA + E D +
Sbjct 1713 NNCYINVACLMLQHLSLKFPKWQWRRPGNEFRSGKPLRFVSLVLAKGSFKFNEPSDSTDF 1772
Query 1709 MTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGR 1768
+ L+ A+L A L +CK CG K GV+AVM+ GTL L G +I C CG
Sbjct 1773 IRVELREADLSGATCDLEFICK-CGVKQEQRKGVDAVMHFGTLDKSGLVKGYNIACTCG- 1830
Query 1769 DATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGA 1828
D + Q F++ S P KL + AN +TG GHYTH+ K D
Sbjct 1831 DKLVHCTQFNVPFLICSNTPEGKKLPDDV-VAANIFTGG-SVGHYTHVKCKPKYQLYDAC 1888
Query 1829 HLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQ 1887
+++K+SE KG TD Y K T + +Y LD V +P L YY + YYT+
Sbjct 1889 NVSKVSEAKGNFTDCLYLKNLKQTFSSVLTTYYLDDVKCVAYKPDLSQYYCESGKYYTKP 1948
Query 1888 PIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVV 1945
I T + NFKL A+ LN GF E +T +P GDVV
Sbjct 1949 IIKAQFRTFEKVEGVYTNFKLV--GHDIAEKLNAKLGFDCNSPFMEYKITEWPTATGDVV 2006
Query 1946 AIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF----KPNTWCLRCLWSTKPVDTSNS 2001
Y + + G KP++W ++ + + +P+ C ++ PVD S
Sbjct 2007 LASDDLYVSRYSGGCVTFGKPVIWRGHEEASLKSLTYFNRPSVVCEN-KFNVLPVDVSEP 2065
Query 2002 FE--------------------VLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIEC 2041
+ ++ E + AC S + V+E QK+
Sbjct 2066 TDRRPVPSAVLVTGAASGADASAISTEPGTAKEQKACASDSVEDQIVME---AQKKSSVT 2122
Query 2042 DVKTTEVVGNVILKP-----------SDEGVKVTQELGHEDLMAAYVENTSITIKKPNEL 2090
V EV N + KP KV + L D+ ++ + NEL
Sbjct 2123 TVAVKEVKLNGVKKPVKWNCSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWTANEL 2182
Query 2091 SLALGLKTIATHGIAAINSVPW--SKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPY 2148
S + T+ + V W SK++ L + K + + Y
Sbjct 2183 SRLINSPTVREY-------VKWGMSKLIIPANLLLLRDEKQEFVAPKVVKAKAIACYGAV 2235
Query 2149 VFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFS----KLF 2204
+ LL+ +T++++ + T +A K KLC A N +++ +S F
Sbjct 2236 KWFLLYCFSWIKFNTDNKVIYT--TEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFF 2290
Query 2205 TIA-MWLLLLSICLGSLIC--------------VTAAFGVLLSNFGAPSYCN--GVRELY 2247
+A ++LL + ++I V + + FG + C+ V +L
Sbjct 2291 LVATVFLLWFNFLYANVILSDFYLPNIGPLPMFVGQIVAWVKTTFGVLTICDFYQVTDLG 2350
Query 2248 LNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQ-VTISSYKLD-LTILGLAAEWV 2305
SS FC GS C +C SG D LD+Y ++ +Q V D +++ L E V
Sbjct 2351 YRSS------FCNGSMVCELCFSGFDMLDNYESINVVQHVVDRRVSFDYISLFKLVVELV 2404
Query 2306 LAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIF 2363
+ Y L+T FY L + MQ+ + F+ + W + + M P ++R YI
Sbjct 2405 IGYSLYTVCFYPLFVLVGMQLLTTWLPEFFMLGTMHWSARLFVFVANMLPAFTLLRFYIV 2464
Query 2364 FASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCK 2423
+ Y ++ H+M GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC
Sbjct 2465 VTAMYKVYCLCRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCT 2524
Query 2424 THNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFD 2483
H WNCLNC+++ G+TFI+ E A DLS + KRP+NPTD + Y V V ++ L+++
Sbjct 2525 KHQWNCLNCNSWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVIEVKQVGCSMRLFYE 2584
Query 2484 KAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMC 2543
+ GQ+ Y+ S FV+++ L + KG +V+V + ++ D++ +A+V+Y+Q +
Sbjct 2585 RDGQRVYDDVSASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLY 2642
Query 2544 QPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVAL 2603
+P+L++++ L++ VS MFD YV + V + L + V AH+ L +GV L
Sbjct 2643 RPMLMVEKKLITTANTGLSVSRTMFDLYVYSLLRHLDVDRKSLTSFVNAAHNSLKEGVQL 2702
Query 2604 DGVLSTFVSAARQG-VVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTP 2662
+ V+ TFV AR+ +D+DV+TK + + + + ++ +EVT +SCNN + TY K + +
Sbjct 2703 EQVMDTFVGCARRKCAIDSDVETKSITKSVMAAVNAGVEVTDESCNNLVPTYVKSDTIVA 2762
Query 2663 RDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCA 2722
DLG I NA+H+ + VAK+ NV+ IW+V + LS L+ ++R A K + +LT
Sbjct 2763 ADLGVLIQNNAKHVQSNVAKAANVACIWSVDAFNQLSADLQHRLRKACVKTGLKIKLTYN 2822
Query 2723 TTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNE 2782
V ++TT SLKGG + S + + A L+C + V + +MP + + D
Sbjct 2823 KQEANVPILTTPFSLKGGAVFSRVLQWLFVANLICFI---VLWALMPTYAVHKSDMQLPL 2879
Query 2783 IIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREIG 2840
+K I +GV RD+ TD CFANK FD W+ G Y+N K+CPVV A+I ++IG
Sbjct 2880 YASFKVIDNGVLRDVSVTDACFANKFNQFDQWYESTFGLVYYRNSKACPVVVAVIDQDIG 2939
Query 2841 FIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFK 2900
+ +P VLR LHF+ F+ CYTP I Y +F S CVL++ CT+
Sbjct 2940 HTLFNVPTKVLR-YGFHVLHFITHAFATDRVQCYTPHMQIPYDNFYASGCVLSSLCTMLA 2998
Query 2901 DAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAE 2959
A G P PYCY ++ + YS L P RY L + I+FP EG VRVV T
Sbjct 2999 HADGTPHPYCYTEGVMHNASLYSSLVPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMT 3058
Query 2960 YCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALD 3019
YCR G CE +E GIC + + WVLNN +YRA+ G FCG +A +LI + LVQP+
Sbjct 3059 YCRVGLCEEAEEGICFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVQPIDFFA 3118
Query 3020 VSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLP 3079
++AS VAG I+AI+V A YY +K +R FG+Y VV N +++ ++F +L + Y L
Sbjct 3119 LTASSVAGAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLS 3178
Query 3080 GVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLR 3139
+Y+ FY Y T YF +++S + HLQW M+ I+P W YV + H W F+ Y R
Sbjct 3179 CLYACFYFYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCITYVAVVVSNHALWLFS-YCR 3237
Query 3140 KRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALD 3199
K + + + TFEE AL TF++ KE Y KL++ + +NRYL+LYNKY+YFSG +D
Sbjct 3238 K-IGTDVRSDGTFEEMALTTFMITKESYCKLKNS--VSDVAFNRYLSLYNKYRYFSGKMD 3294
Query 3200 TTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMV 3258
T +YREAAC LAKA+ F+ N+G DVLYQPP S+T++ LQSG KM P+ KVE C+V
Sbjct 3295 TATYREAACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCVV 3354
Query 3259 QVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVI 3318
VT G TLNGLWLDD VYCPRHVIC++ DM +P+Y +LL R ++ F V + + L V+
Sbjct 3355 SVTYGNMTLNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSDRMSLTVM 3414
Query 3319 GHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKG 3378
+ MQ LL L V NP TPKY F ++PG+TF+VLA YNG P G + MR +HTIKG
Sbjct 3415 SYQMQGSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVVMRSSHTIKG 3474
Query 3379 SFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDT 3438
SFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q Q D
Sbjct 3475 SFLCGSCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDY 3534
Query 3439 TITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTG 3498
T T+NV+AWLYAA++N WF+ + +L +FN+ AM + + D V L L++ TG
Sbjct 3535 TQTVNVVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTG 3592
Query 3499 IAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHH 3558
+ V + AA+K L +G G+ ILGS +LEDE TP DV +Q +GV Q K +++KGT
Sbjct 3593 VTVEQVLAAIKR-LHSGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVIKGTCC 3651
Query 3559 WMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLL 3618
W+L + I+ +W++F +V + L TL + AMLL+KHKH +L ++++
Sbjct 3652 WILASTFLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVIFAMLLIKHKHLYLTMYIM 3710
Query 3619 PSLATVAYFNMVYMPASWVMRIM--TWLELADTSLSGYRLKDCVMYASA-LVLLILMTAR 3675
P L T+ Y N + + R + WL ++ Y D V+Y LV ++ +T R
Sbjct 3711 PVLCTLFYTNYLVVGYKQSFRGLAYAWLSYFVPAVD-YTYMDEVLYGVVLLVAMVFVTMR 3769
Query 3676 TVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAI 3735
++ D ++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA A
Sbjct 3770 SINHDVFSTMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAK 3825
Query 3736 VFVCVEYYPLLFITG-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVST 3794
V +L+ T ++ ++L Y +GY CCCY+G+ LLN FR+ LGVY+Y +S
Sbjct 3826 VIAKWLAVNVLYFTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISV 3885
Query 3795 QEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQ 3854
QE RYMN+ GL PP++S +A LN KLLGIGG P I+V+ +QS+++DVKC +VVLL+ LQ
Sbjct 3886 QELRYMNANGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQ 3945
Query 3855 QLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLC 3908
L + S+SKLW C LHN+IL D + AF+K+ LL VL + AVD I +
Sbjct 3946 HLHIASNSKLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVS 4005
Query 3909 EEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSE 3967
++ + + LQA+ SEF ++ S+ Y A++ ++A A+G + + +K+L+K+ N+AKS
Sbjct 4006 DDYVRDNTVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSA 4065
Query 3968 FDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIIN 4027
++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++
Sbjct 4066 YERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILD 4125
Query 4028 NARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQ 4087
NA GCVPLN IP T+ L ++VPD + D TYA +W IQ + DAD + Q
Sbjct 4126 NAVKGCVPLNAIPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQ 4185
Query 4088 LSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNA 4145
L+EI+++++ WPL+++A R N S V LQNNEL P LR +G+ +
Sbjct 4186 LNEIDVNST----WPLVISANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNC--NIPT 4239
Query 4146 LAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYL 4205
YYN + G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYL
Sbjct 4240 QCYYNTTGTGKIVYAILSDCDGLKYTKIVKEDGN-CVVLELDPPCKFSVQDVKGLKIKYL 4298
Query 4206 YFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGG 4265
YF+KG N L RG V+G+L++TVRLQAG ATE +NS +LS CAF+VDP K Y DY+ GG
Sbjct 4299 YFVKGCNTLARGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIQQGG 4358
Query 4266 QPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGK 4325
P+TNCVKMLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK
Sbjct 4359 VPVTNCVKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGK 4418
Query 4326 YVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSC 4360
+VQ+P DPV + L + VC VCG W+ CSC
Sbjct 4419 FVQVPLG-IKDPVSYVLTHDVCQVCGFWRDGSCSC 4452
Score = 74.7 bits (182), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 98/390 (25%), Positives = 165/390 (42%), Gaps = 45/390 (12%)
Query 569 ILDGISEQSLRLVDA-------MVYTSDLLTNSVIIMAYVTGGLVQQTSQWLSNLLGTTV 621
+LDG+ +S L+ + MV S + + + MA + V+ ++++ + G
Sbjct 576 LLDGLVPRSYYLIKSGQAFTSLMVNFSREVVDMCMDMALLFMHDVKVATKYVKKVTGKVA 635
Query 622 EK--------LRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
+ +R I EW + + W + L+ G+F + G I + + +
Sbjct 636 VRFKALGIAVVRKITEWFDLAVDTAAS--AAGWLCYQ-LVNGLFAVANGVITFIQE-VPE 691
Query 674 CVKCFIDVVNKALEMCIDQVTIA---GAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLL 730
VK F+D ++ ID ++++ G + V +A SK +Y + K +
Sbjct 692 LVKNFVDKFKTFFKVLIDSMSVSILSGLTVVKTASNRVCLAGSK-VYE--VVQKSLPAYI 748
Query 731 MPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGEL--EALETPVDSFTNGAIVGTPVCVNGL 788
MP+ E T L G+ V + V + L + P SF IV + L
Sbjct 749 MPVGC-SEATCLVGEIEPAVFEDDVVDVVKAPLTYQGCCKPPSSFEKICIV------DKL 801
Query 789 MLLEIKDKEQYCAL---SPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGYKNVRITF 844
+ + D+ + + G+L F G K V F + V EV + ++I F
Sbjct 802 YMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAG----KKVVFNDKPKVKEVPSTRKIKIIF 857
Query 845 ELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD---LLTNMGIDLDEW 901
LD D VL++ CS + V+ + E VV +AV TL P + + T + L+
Sbjct 858 ALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVESTLSPCKEHGVIGTKVCALLERL 917
Query 902 SVATFYLFDDAGEENFSSRMYCSFYPPDEE 931
YLFD+ GEE +SRMYCSF PDE+
Sbjct 918 VDDYVYLFDEGGEEVIASRMYCSFSAPDED 947
Score = 60.1 bits (144), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 54/149 (36%), Positives = 77/149 (52%), Gaps = 2/149 (1%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T NV D++K + VIVN AN + HG GVAGA+ KA A E+ D +K
Sbjct 1319 ITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKAFINETADMVKA 1378
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQDILLAPLLSA 1129
G VGG +G L KK L++VGP+ + E LL+ AY++ N D ++ L+SA
Sbjct 1379 QGVCQVGGCYESTGGKLCKKVLNIVGPDARGHGNECYSLLERAYQHINKCDNVVTTLISA 1438
Query 1130 GIFGAKPLQSLQVCVQTVRTQVYIAVNDK 1158
GIF SL + V V + N++
Sbjct 1439 GIFSVPTDVSLTYLLGVVTKNVILVSNNQ 1467
Score = 41.2 bits (95), Expect = 0.51, Method: Compositional matrix adjust.
Identities = 50/202 (25%), Positives = 82/202 (41%), Gaps = 21/202 (10%)
Query 1573 PTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSE-AFEYYHTLDESFLGRYMSALNHTK 1631
P ++ D+ K++ + E +T P+D T AF+ ++ S S H K
Sbjct 1047 PDQVEAFDIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPSDETHFK 1106
Query 1632 KWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALI 1691
V G S NC+L S L+ +Q L ++F +Q+ + +AG F +
Sbjct 1107 ------VCGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKL 1160
Query 1692 LAYSNKTV--GELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMG 1749
+ + K++ + G V + L S K N C CG + L G++AV + G
Sbjct 1161 VKSAPKSIILPQGGYVADFAYFFLSQC---SFKVHANWRCLKCGME-LKLQGLDAVFFYG 1216
Query 1750 TLSYDNLKTGVSIPCVCGRDAT 1771
+ VS C CG T
Sbjct 1217 DV--------VSHMCKCGNSMT 1230
>sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=1a PE=3 SV=1
Length=4441
Score = 1810 bits (4688), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1058/2863 (37%), Positives = 1570/2863 (55%), Gaps = 108/2863 (4%)
Query 1543 KTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
K I V TVD N + + + +G+ G + DG DVTK+K + K + +
Sbjct 1620 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1679
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ 1662
A + D+ L Y + L KW G S + + NNCY++ L LQ
Sbjct 1680 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1738
Query 1663 LEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAK 1722
+ +KFN QEA+Y RAG AL+LA + E D + + +L+ A+L A
Sbjct 1739 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1798
Query 1723 RVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVC-GRDATQYLVQQESSF 1781
L ++C CG K + GV+AVM+ GTL+ +L G I C C GR + + F
Sbjct 1799 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGR--IVHCTKLNVPF 1855
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S P L + AN + G GHYTH+ D + K + G +T
Sbjct 1856 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1913
Query 1842 DVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLP-- 1898
D Y K + T T +Y LD V P L YY + YYT +PI +P
Sbjct 1914 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKV 1972
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGFTKPAS-RELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL + LN GF E VT +P GDVV Y +
Sbjct 1973 DGVYTNFKLVGHDI--CAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYF 2030
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKP-VDTSNSFEVLAVEDTQGMDNL 2016
KG + KP++W + + + + KP + N + VL+V D++
Sbjct 2031 KGCETFGKPVIWLCHDEASLNSLT---------YFNKPSFKSENRYSVLSV------DSV 2075
Query 2017 ACESQQPTSEEVVENPTIQKEV-IECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
+ ESQ V+E+ KEV ++ KT ++ +I+ + +KV + L D+
Sbjct 2076 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2135
Query 2076 YVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAK 2135
Y+ + NELS + T+ + I + L ++ Q +
Sbjct 2136 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPITIPIDLLCLRD-DNQTLLVPKIFKA 2194
Query 2136 RLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYV 2195
R + F ++ ++F +F L FT T IA ++ L L
Sbjct 2195 RAIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAFQTF 2248
Query 2196 KSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGV----------------LLSNFGAPSY 2239
+ F K F + + L + + + F + + + FG +
Sbjct 2249 RWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTI 2308
Query 2240 CNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL--DLTI 2297
C+ +L + T FC GSF C +C SG D LD+Y A++ +Q + L +++
Sbjct 2309 CDFYSKLGVG----FTSHFCNGSFICELCYSGFDMLDTYAAIDFVQYEVDRRVLFDYVSL 2364
Query 2298 LGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVS 2355
+ L E V+ Y L+T +FY L +Q+F + F+ + WL+ FI+ + M P
Sbjct 2365 VKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAF 2424
Query 2356 AMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYA 2415
++R YI + Y + HI+ GC + C+ CYKRN + RV+C+TIV G+ R + + A
Sbjct 2425 VLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITA 2484
Query 2416 NGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKN 2475
NGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2485 NGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVG 2544
Query 2476 GALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSAS 2535
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V +S D + +A
Sbjct 2545 CMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVV--VESDADRANFLNAV 2602
Query 2536 VYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHS 2595
V+Y+Q + +PILL+D+ L++ + V+ MFD YVDTF + F V + V AH+
Sbjct 2603 VFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVNIAHA 2662
Query 2596 ELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTY 2654
L +GV L+ VL TFV R+ +D+DV+T+ + + + + + LE T ++ NN + TY
Sbjct 2663 SLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVPTY 2722
Query 2655 NKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNN 2714
K +N+ DLG I A+H+ VAK+ N+S IW + + L+ L+ +++ A K
Sbjct 2723 LKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDTFNQLTADLQHKLKKACVKTG 2782
Query 2715 IPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLS 2774
+ +LT V ++TT SLKGG ++S ++ +L+C + + + ++P +++
Sbjct 2783 LKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPTYSVY 2839
Query 2775 IHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGS--YKNDKSCPVVA 2832
D + +K I +GV RDI D CFANK FD W+ GS Y N CP+V
Sbjct 2840 KSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSFYYHNSMDCPIVV 2899
Query 2833 AIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVL 2892
A++ +IG + +P VLR LHFL F++ CYTP I Y+DF S CVL
Sbjct 2900 AVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVL 2958
Query 2893 AAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVR 2951
++ CT+FK G P PYCY +++ + Y+ L P TRY L + + I+FP+ EG VR
Sbjct 2959 SSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVR 3018
Query 2952 VVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPL 3011
+V T YCR G CE +E GIC + + WVLNN++YR++ G FCG D +L F+ L
Sbjct 3019 IVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQFFSSL 3078
Query 3012 VQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCL 3071
++P+ ++AS + G I+AI+V YY +K +R FG+Y VV N +++ ++F +L +
Sbjct 3079 IRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFV 3138
Query 3072 VPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCH 3131
Y VY+ FY Y+T YF +++S + HLQW M+ I+PFW YV + H
Sbjct 3139 FQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVL 3198
Query 3132 WFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKY 3191
W F+ Y RK + N STFEE +L TF++ K+ Y +L++ + YNRYL+LYNKY
Sbjct 3199 WLFS-YCRK-IGVNVCNDSTFEETSLTTFMITKDSYCRLKNS--VSDVAYNRYLSLYNKY 3254
Query 3192 KYFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPS 3250
+Y+SG +DT +YREAAC LAKA+ F+ N+G DVLYQPP S++++ LQSG KM P+
Sbjct 3255 RYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPT 3314
Query 3251 GKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQA 3310
K+E C+V VT G+ TLNGLWLDD VYCPRHVIC + +M P+Y LL R + F + +
Sbjct 3315 SKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDFTIMS 3374
Query 3311 GNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAM 3370
G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + M
Sbjct 3375 GRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAFHVTM 3434
Query 3371 RPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQT 3430
R ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q
Sbjct 3435 RSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYRDAQV 3494
Query 3431 AQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL 3490
Q D T+NV+AWLYAA++N WF+ ++ DFN+ AM + + D V L
Sbjct 3495 VQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADLV--L 3552
Query 3491 GPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFK 3550
L++ TG+++ + AA+K L G GR ILGS EDE P DV +Q +GV Q K K
Sbjct 3553 DALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTK 3611
Query 3551 KIVKGTHHWMLL-TFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHK 3609
+ +K T +W+L+ TFL S I+ +W++F ++ + TL ++ + MLLVKHK
Sbjct 3612 RFIKETIYWILISTFLFS-CIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLVKHK 3669
Query 3610 HAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASAL-V 3667
H +L ++++P L T+ Y N +V + WL +++ + + V Y L V
Sbjct 3670 HFYLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYE-VFYGCILCV 3728
Query 3668 LLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTT 3727
I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ T + TT
Sbjct 3729 FAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLFITAFLGTYTW----TT 3784
Query 3728 IMFLARA-IVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLG 3786
I+ LA A IV + F ++ I+L Y F+GY CY+G F LLN FR+ +G
Sbjct 3785 ILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMG 3844
Query 3787 VYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTS 3846
VY+Y +S QE RYMN+ GL PP++S +A LN+KLLGIGG P I+V+ +QSK++DVKC +
Sbjct 3845 VYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCAN 3904
Query 3847 VVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD--- 3903
VVLL+ LQ L V S+S+LW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3905 VVLLNCLQHLHVASNSRLWQYCSILHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDTKC 3964
Query 3904 ---INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKK 3959
I+ + ++ + + LQA+ SEF ++ S+ Y A++ A +G ++ +K+L+K
Sbjct 3965 LASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEK 4024
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN
Sbjct 4025 ACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDN 4084
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
ALN+I++NA GCVPLN IP A L +++PD + D YA ++W IQ V
Sbjct 4085 QALNSILDNAVKGCVPLNAIPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQTVQ 4144
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGTTQ 4137
DAD QL++I++D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4145 DADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDM 4200
Query 4138 TACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTP 4197
+ YYNN GR V A+LSD LK+ + K DG + EL+PPC+F
Sbjct 4201 NC--NIPTQCYYNNGSSGRIVYAVLSDVDGLKYTKIIKDDGNCVV-LELDPPCKFSIQDV 4257
Query 4198 KGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAY 4257
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VDP K Y
Sbjct 4258 KGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKTY 4317
Query 4258 KDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPK 4317
DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4318 LDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDVD 4377
Query 4318 GFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSC 4360
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC
Sbjct 4378 GLCKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSC 4419
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 55/157 (35%), Positives = 80/157 (51%), Gaps = 2/157 (1%)
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
L +T NV DI+ A+ VIVN AN H+ HGGGVA A+ A KE+ +
Sbjct 1328 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1387
Query 1070 KLNGPLTVGGSCLLSGHNLAKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQDILLAPLL 1127
K G VG + +G L K L++VGP+ + + LL AY++ N+ D L+ L+
Sbjct 1388 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1447
Query 1128 SAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
SAGIF SL + V QV + N+K ++ +
Sbjct 1448 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDII 1484
Score = 80.1 bits (196), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 90/362 (25%), Positives = 158/362 (44%), Gaps = 48/362 (13%)
Query 616 LLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCV 675
LLGTT+ + + W L A W +L L+ G+F + + + I D
Sbjct 615 LLGTTL--VNKMVNWFNTMLDASAP--ATGW-LLYQLLNGLFVVSQANFNFVA-LIPDYA 668
Query 676 KCFIDVVNKALEMCIDQVTIAGAK----LRSLN-----LGEVFIAQSKGLYRQCIRGKEQ 726
K ++ ++ ++ VT+ K L+++N +G F S GL I G
Sbjct 669 KILVNKFYTFFKLLLECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGL----IPG--- 721
Query 727 LQLLMPLKA-PKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSF---TNGAIVGTP 782
++P A +++ F EG +E V++++ +E +++ + S+ V
Sbjct 722 --FVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEKI 772
Query 783 VCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGG--APIKG--VTFGED-TVWEVQGY 837
++ + + + DK P ++ N+ L P G V F E V E+
Sbjct 773 CIIDNMYMGKCGDK-----FFPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 838 KNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD---LLTNM 894
V++ F+LD D +L + CS + VE G V +F VV +A+ L D + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKDHPVVGYQV 887
Query 895 GIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTE 954
L++ + YLFD+AG+E +SRMYC+F D E+ +E E+ ID E +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 955 DD 956
+D
Sbjct 948 ED 949
Score = 44.3 bits (103), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 38/137 (28%), Positives = 60/137 (44%), Gaps = 14/137 (10%)
Query 1637 QVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSN 1696
+V GL S NC+L SVLL +Q+L KF A++ + + G +F +L
Sbjct 1117 KVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTTIP 1176
Query 1697 KTV--GELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYD 1754
K + + G V + L ++ + N C CG + L G++AV + G +
Sbjct 1177 KAIVLPQGGYVADFAYWFLNQFDINAYA---NWCCLKCG-FSFDLNGLDAVFFYGDI--- 1229
Query 1755 NLKTGVSIPCVCGRDAT 1771
VS C CG + T
Sbjct 1230 -----VSHVCKCGHNMT 1241
>sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=1a PE=3 SV=1
Length=4421
Score = 1808 bits (4684), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1062/2868 (37%), Positives = 1571/2868 (55%), Gaps = 118/2868 (4%)
Query 1543 KTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
K I V TVD N + + + +G+ G + DG DVTK+K + K + +
Sbjct 1600 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1659
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ 1662
A + D+ L Y + L KW G S + + NNCY++ L LQ
Sbjct 1660 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1718
Query 1663 LEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAK 1722
+ +KFN QEA+Y RAG AL+LA + E D + + +L+ A+L A
Sbjct 1719 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1778
Query 1723 RVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVC-GRDATQYLVQQESSF 1781
L ++C CG K + GV+AVM+ GTL+ +L G I C C GR + + F
Sbjct 1779 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGR--IVHCTKLNVPF 1835
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S P L + AN + G GHYTH+ D + K + G +T
Sbjct 1836 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1893
Query 1842 DVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLP-- 1898
D Y K + T T +Y LD V P L YY + YYT +PI +P
Sbjct 1894 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKV 1952
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGFTKPAS-RELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL LN GF E VT +P GDVV Y +
Sbjct 1953 DGVYTNFKLV--GHDICAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYF 2010
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKP-VDTSNSFEVLAVEDTQGMDNL 2016
KG + KP++W + + + + KP + N + VL+V D++
Sbjct 2011 KGCETFGKPVIWFCHDEASLNSLT---------YFNKPSFKSENRYSVLSV------DSV 2055
Query 2017 ACESQQPTSEEVVENPTIQKEV-IECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
+ ESQ V+E+ KEV ++ KT ++ +I+ + +KV + L D+
Sbjct 2056 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2115
Query 2076 YVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAK 2135
Y+ + NELS + T+ + I + L ++ Q +
Sbjct 2116 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPITIPIDLLCLRD-DNQTLLVPKIFKA 2174
Query 2136 RLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYV 2195
R + F ++ ++F +F L FT T IA ++ L L
Sbjct 2175 RAIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAFQTF 2228
Query 2196 KSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGV----------------LLSNFGAPSY 2239
+ F K F + + L + + + F + + + FG +
Sbjct 2229 RWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTI 2288
Query 2240 CNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL--DLTI 2297
C+ +L + T FC GSF C +C SG D LD+Y A++ +Q + L +++
Sbjct 2289 CDFYSKLGVG----FTSHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDYVSL 2344
Query 2298 LGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVS 2355
+ L E V+ Y L+T +FY L +Q+F + F+ + WL+ FI+ + M P
Sbjct 2345 VKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAF 2404
Query 2356 AMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYA 2415
++R YI + Y + HI+ GC + C+ CYKRN + RV+C+TIV G+ R + + A
Sbjct 2405 VLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITA 2464
Query 2416 NGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKN 2475
NGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2465 NGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVG 2524
Query 2476 GALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSAS 2535
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + S D + +A
Sbjct 2525 CMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVE--SDADRANFLNAV 2582
Query 2536 VYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHS 2595
V+Y+Q + +PILL+D+ L++ + V+ MFD YVDTF + F V + V AH+
Sbjct 2583 VFYAQSLYRPILLVDKKLITTACNGISVTQIMFDVYVDTFMSHFDVDRKSFNNFVNIAHA 2642
Query 2596 ELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTY 2654
L +GV L+ VL TFV R+ +D+DV+T+ + + + + + LE T ++ NN + TY
Sbjct 2643 SLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVPTY 2702
Query 2655 NKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNN 2714
K +N+ DLG I A+H+ VAK N+S IW + + L+ L+ +++ A K
Sbjct 2703 LKSDNIVAADLGVLIQNGAKHVQGNVAKVANISCIWFIDAFNQLTADLQHKLKKACVKTG 2762
Query 2715 IPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLS 2774
+ +LT V ++TT SLKGG ++S ++ +L+C + + + ++P +++
Sbjct 2763 LKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPTYSVY 2819
Query 2775 IHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGS--YKNDKSCPVVA 2832
D + +K I +GV RDI D CFANK FD W+ GS Y N CP+V
Sbjct 2820 KSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDCPIVV 2879
Query 2833 AIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVL 2892
A++ +IG + +P VLR LHFL F++ CYTP I Y+DF S CVL
Sbjct 2880 AVMDEDIGSTMFNVPTKVLR-YGFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVL 2938
Query 2893 AAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVR 2951
++ CT+FK G P PYCY +++ + Y+ L P TRY L + + I+FP+ EG VR
Sbjct 2939 SSLCTMFKRGDGTPHPYCYTDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVR 2998
Query 2952 VVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPL 3011
+V T YCR G CE +E GIC + + WVLNN++YR++ G FCG D +L F+ L
Sbjct 2999 IVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDFFDLFYQFFSSL 3058
Query 3012 VQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCL 3071
++P+ ++AS + G I+AI+V YY +K +R FG+Y VV N +++ ++F +L +
Sbjct 3059 IRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFV 3118
Query 3072 VPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCH 3131
Y VY+ FY Y+T YF +++S + HLQW M+ I+PFW YV + H
Sbjct 3119 FQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVL 3178
Query 3132 WFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKY 3191
W F+ Y RK + N + STFEE +L TF++ K+ Y +L++ + YNRYL+LYNKY
Sbjct 3179 WLFS-YCRK-IGVNVCSDSTFEETSLTTFMITKDSYCRLKNS--VSDVAYNRYLSLYNKY 3234
Query 3192 KYFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPS 3250
+Y+SG +DT +YREAAC LAKA+ F+ N+G DVLYQPP S++++ LQSG KM P+
Sbjct 3235 RYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPT 3294
Query 3251 GKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQA 3310
K+E C+V VT G+ TLNGLWLDD VYCPRHVIC + +M P+Y LL R + F + +
Sbjct 3295 SKIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDFTIMS 3354
Query 3311 GNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAM 3370
G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + M
Sbjct 3355 GRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAFHVTM 3414
Query 3371 RPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQT 3430
R ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q
Sbjct 3415 RSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGNFYGPYRDAQV 3474
Query 3431 AQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL 3490
Q D T+NV+AWLYAA++N WF+ ++ DFN+ AM + + D V L
Sbjct 3475 VQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADLV--L 3532
Query 3491 GPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFK 3550
L++ TG+++ + AA+K L G GR ILGS EDE P DV +Q +GV Q K K
Sbjct 3533 DALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTK 3591
Query 3551 KIVKGTHHWMLL-TFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHK 3609
+ +K T +W+L+ TFL S I+ +W++F ++ + TL ++ + MLLVKHK
Sbjct 3592 RFIKETIYWILISTFLFS-CIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLVKHK 3649
Query 3610 HAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASAL-V 3667
H +L ++++P L T+ Y N +V + WL +++ + + V Y L V
Sbjct 3650 HFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYE-VFYGCILCV 3708
Query 3668 LLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTT 3727
I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ T + TT
Sbjct 3709 FAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLFITAFLGTYTW----TT 3764
Query 3728 IMFLARA-IVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLG 3786
I+ LA A IV + F ++ I+L Y F+GY CY+G F LLN FR+ +G
Sbjct 3765 ILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMG 3824
Query 3787 VYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTS 3846
VY+Y +S QE RYMN+ GL PP++S +A LN+KLLGIGG P I+V+ +QSK++DVKC +
Sbjct 3825 VYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCAN 3884
Query 3847 VVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD--- 3903
VVLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL S AVD
Sbjct 3885 VVLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFSNPAAVDTKC 3944
Query 3904 ---INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKK 3959
I+ + ++ + + LQA+ SEF ++ S+ Y A++ A +G ++ +K+L+K
Sbjct 3945 LASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEK 4004
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN
Sbjct 4005 ACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDN 4064
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
ALN+I++NA GCVPL+ IP A L +++PD + D TYA ++W IQ V
Sbjct 4065 QALNSILDNAVKGCVPLSAIPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQTVQ 4124
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGT-- 4135
DAD QL++I++D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4125 DADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDI 4180
Query 4136 ---TQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRF 4192
T C YYNN GR V A+LSD LK+ + K DG + EL+PPC+F
Sbjct 4181 NCNIPTQC-------YYNNVSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKF 4232
Query 4193 VTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVD 4252
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VD
Sbjct 4233 SIQDVKGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVD 4292
Query 4253 PAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHID 4312
P K Y DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++
Sbjct 4293 PKKTYLDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVE 4352
Query 4313 HPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSC 4360
HP+ G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC
Sbjct 4353 HPDVDGICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSC 4399
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 55/157 (35%), Positives = 80/157 (51%), Gaps = 2/157 (1%)
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
L +T NV DI+ A+ VIVN AN H+ HGGGVA A+ A KE+ +
Sbjct 1308 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1367
Query 1070 KLNGPLTVGGSCLLSGHNLAKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQDILLAPLL 1127
K G VG + +G L K L++VGP+ + + LL AY++ N+ D L+ L+
Sbjct 1368 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1427
Query 1128 SAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
SAGIF SL + V QV + N+K ++ +
Sbjct 1428 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDII 1464
Score = 78.6 bits (192), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 89/362 (25%), Positives = 158/362 (44%), Gaps = 48/362 (13%)
Query 616 LLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCV 675
LLGTT+ + + W L A W +L L+ G F + + + + I D
Sbjct 615 LLGTTL--VNKMVNWFNTMLDASAP--ATGW-LLYQLLNGFFVVSQANLNFVA-LIPDYA 668
Query 676 KCFIDVVNKALEMCIDQVTIAGAK----LRSLN-----LGEVFIAQSKGLYRQCIRGKEQ 726
K ++ ++ ++ VT+ K L+++N +G F S GL I G
Sbjct 669 KILVNKFYTFFKLLLECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGL----IPG--- 721
Query 727 LQLLMPLKA-PKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSF---TNGAIVGTP 782
++P A +++ F EG +E V++++ +E +++ + S+ V
Sbjct 722 --FVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEKI 772
Query 783 VCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGG--APIKG--VTFGED-TVWEVQGY 837
++ + + + DK P ++ N+ L P G V F E V E+
Sbjct 773 CIIDNMYMGKCGDK-----FFPIVMNDKNICLLDHAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 838 KNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD---LLTNM 894
V++ F+LD D +L + CS + VE G V +F VV +A+ L + + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQV 887
Query 895 GIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTE 954
L++ + YLFD+AG+E +SRMYC+F D E+ +E E+ ID E +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 955 DD 956
+D
Sbjct 948 ED 949
Score = 44.3 bits (103), Expect = 0.062, Method: Compositional matrix adjust.
Identities = 38/137 (28%), Positives = 60/137 (44%), Gaps = 14/137 (10%)
Query 1637 QVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSN 1696
+V GL S NC+L SVLL +Q+L KF A++ + + G +F +L
Sbjct 1097 KVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTTIP 1156
Query 1697 KTV--GELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYD 1754
K + + G V + L ++ + N C CG + L G++AV + G +
Sbjct 1157 KAIVLPQGGYVADFAYWFLNQFDINAYA---NWCCLKCG-FSFDLNGLDAVFFYGDI--- 1209
Query 1755 NLKTGVSIPCVCGRDAT 1771
VS C CG + T
Sbjct 1210 -----VSHVCKCGHNMT 1221
>sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=1a PE=1 SV=1
Length=4471
Score = 1803 bits (4671), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 1060/2863 (37%), Positives = 1572/2863 (55%), Gaps = 108/2863 (4%)
Query 1543 KTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
K I V TVD N + + + +G+ G + DG DVTK+K + K + +
Sbjct 1650 KKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENLS 1709
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ 1662
A + D+ L Y + L KW G S + + NNCY++ L LQ
Sbjct 1710 LADISAVQSSFGFDQQQLLAYYNFLT-VCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQH 1768
Query 1663 LEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAK 1722
+ +KFN QEA+Y RAG AL+LA + E D + + +L+ A+L A
Sbjct 1769 INLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGAI 1828
Query 1723 RVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVC-GRDATQYLVQQESSF 1781
L ++C CG K + GV+AVM+ GTL+ +L G I C C GR + + F
Sbjct 1829 CELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAGR--IVHCTKLNVPF 1885
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S P L + AN + G GHYTH+ D + K + G +T
Sbjct 1886 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1943
Query 1842 DVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLP-- 1898
D Y K + T T +Y LD V P L YY + YYT +PI +P
Sbjct 1944 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYT-KPIIKAQFKPFAKV 2002
Query 1899 NASFDNFKLTCSNTKFADDLNQMTGFTKPAS-RELSVTFFPDLNGDVVAIDYRHYSASFK 1957
+ + NFKL + LN GF E VT +P GDVV Y +
Sbjct 2003 DGVYTNFKLVGHD--ICAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYF 2060
Query 1958 KGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKP-VDTSNSFEVLAVEDTQGMDNL 2016
KG + KP++W + + + + KP + N + VL+V D++
Sbjct 2061 KGCETFGKPVIWFCHDEASLNSLT---------YFNKPSFKSENRYSVLSV------DSV 2105
Query 2017 ACESQQPTSEEVVENPTIQKEV-IECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
+ ESQ V+E+ KEV ++ KT ++ +I+ + +KV + L D+
Sbjct 2106 SEESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDM 2165
Query 2076 YVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAK 2135
Y+ + NELS + T+ + I + L ++ Q +
Sbjct 2166 YLTGCDYVVWVANELSRLVKSPTVREYIRYGIKPITIPIDLLCLRD-DNQTLLVPKIFKA 2224
Query 2136 RLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYV 2195
R + F ++ ++F +F L FT T IA ++ L L
Sbjct 2225 RAIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAFQTF 2278
Query 2196 KSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGV----------------LLSNFGAPSY 2239
+ F K F + + L + + + F + + + FG +
Sbjct 2279 RWSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTI 2338
Query 2240 CNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL--DLTI 2297
C+ +L + T FC GSF C +C SG D LD+Y A++ +Q + L +++
Sbjct 2339 CDFYSKLGVG----FTSHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDYVSL 2394
Query 2298 LGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVS 2355
+ L E V+ Y L+T +FY L +Q+F + F+ + WL+ FI+ + M P
Sbjct 2395 VKLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAF 2454
Query 2356 AMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYA 2415
++R YI + Y + HI+ GC + C+ CYKRN + RV+C+TIV G+ R + + A
Sbjct 2455 VLLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITA 2514
Query 2416 NGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKN 2475
NGG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2515 NGGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVG 2574
Query 2476 GALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSAS 2535
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V +S D + +A
Sbjct 2575 CMMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVV--VESDADRANFLNAV 2632
Query 2536 VYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHS 2595
V+Y+Q + +PILL+D+ L++ + V+ MFD YVDTF + F V + V AH+
Sbjct 2633 VFYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVNIAHA 2692
Query 2596 ELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTY 2654
L +GV L+ VL TFV R+ +D+DV+T+ + + + + + LE T ++ NN + TY
Sbjct 2693 SLREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVPTY 2752
Query 2655 NKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNN 2714
K +N+ DLG I A+H+ VAK+ N+S IW + + L+ L+ +++ A K
Sbjct 2753 LKSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDAFNQLTADLQHKLKKACVKTG 2812
Query 2715 IPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLS 2774
+ +LT V ++TT SLKGG ++S ++ +L+C + + + ++P +++
Sbjct 2813 LKLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFVSLICFI---LLWALLPTYSVY 2869
Query 2775 IHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGS--YKNDKSCPVVA 2832
D + +K I +GV RDI D CFANK FD W+ GS Y N CP+V
Sbjct 2870 KSDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDCPIVV 2929
Query 2833 AIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVL 2892
A++ +IG + +P VLR LHFL F++ CYTP I Y+DF S CVL
Sbjct 2930 AVMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVL 2988
Query 2893 AAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVR 2951
++ CT+FK G P PYCY +++ + Y+ L P TRY L + + I+FP+ EG VR
Sbjct 2989 SSLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVR 3048
Query 2952 VVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPL 3011
+V T YCR G CE +E GIC + + WVLNN++YR++ G FCG D +L F+ L
Sbjct 3049 IVRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQFFSSL 3108
Query 3012 VQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCL 3071
++P+ ++AS + G I+AI+V YY +K +R FG+Y VV N +++ ++F +L +
Sbjct 3109 IRPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVVVWCINFLMLFV 3168
Query 3072 VPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCH 3131
Y VY+ FY Y+T YF +++S + HLQW M+ I+PFW YV + H
Sbjct 3169 FQVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVL 3228
Query 3132 WFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKY 3191
W F+ Y RK + N + STFEE +L TF++ K+ Y +L++ + YNRYL+LYNKY
Sbjct 3229 WLFS-YCRK-IGVNVCSDSTFEETSLTTFMITKDSYCRLKNS--VSDVAYNRYLSLYNKY 3284
Query 3192 KYFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPS 3250
+Y+SG +DT +YREAAC LAKA+ F+ N+G DVLYQPP S++++ LQSG KM P+
Sbjct 3285 RYYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPT 3344
Query 3251 GKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQA 3310
K+E C+V VT G+ TLNGLWLDD VYCPRHVIC++ +M P+Y LL R + F + +
Sbjct 3345 SKIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCRVTLGDFTIMS 3404
Query 3311 GNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAM 3370
G + L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + M
Sbjct 3405 GRMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNGRPQGAFHVTM 3464
Query 3371 RPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQT 3430
R ++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q
Sbjct 3465 RSSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYRDAQV 3524
Query 3431 AQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDIL 3490
Q D T+NV+AWLYAA++N WF+ + DFN+ AM + + D V L
Sbjct 3525 VQLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFSQVKADLV--L 3582
Query 3491 GPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFK 3550
L++ TG+++ + AA+K L G GR ILGS EDE P DV +Q +GV Q K K
Sbjct 3583 DALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTK 3641
Query 3551 KIVKGTHHWMLL-TFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHK 3609
+ +K T +W+L+ TFL S I+ +W++F ++ + TL ++ + MLLVKHK
Sbjct 3642 RFIKETIYWILISTFLFS-CIISAFVKWTIFMYI-NTHMIGVTLCVLCFVSFMMLLVKHK 3699
Query 3610 HAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASAL-V 3667
H +L ++++P L T+ Y N +V + WL +++ + + V Y L V
Sbjct 3700 HFYLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYE-VFYGCILCV 3758
Query 3668 LLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTT 3727
I +T ++ D ++ + ++TL+ Y+G+ L++ + ++ T + TT
Sbjct 3759 FAIFITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLFITAFLGTYTW----TT 3814
Query 3728 IMFLARA-IVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLG 3786
I+ LA A IV + F ++ I+L Y F+GY CY+G F LLN FR+ +G
Sbjct 3815 ILSLAIAKIVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMG 3874
Query 3787 VYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTS 3846
VY+Y +S QE RYMN+ GL PP++S +A LN+KLLGIGG P I+V+ +QSK++DVKC +
Sbjct 3875 VYNYKISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCAN 3934
Query 3847 VVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD--- 3903
VVLL+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL + AVD
Sbjct 3935 VVLLNCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDTKC 3994
Query 3904 ---INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKK 3959
I+ + ++ + + LQA+ SEF ++ S+ Y A++ A +G ++ +K+L+K
Sbjct 3995 LASIDEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEK 4054
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN
Sbjct 4055 ACNIAKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDN 4114
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
ALN+I++NA GCVPL+ IP A L +V+PD + D TYA ++W IQ V
Sbjct 4115 QALNSILDNAVKGCVPLSAIPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHIQTVQ 4174
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVK--LQNNELSPVALRQMSCAAGTTQ 4137
DAD QL++I++D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4175 DADGINKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDM 4230
Query 4138 TACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTP 4197
+ YYNN GR V A+LSD LK+ + K DG + EL+PPC+F
Sbjct 4231 NC--NIPTQCYYNNGSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFSIQDV 4287
Query 4198 KGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAY 4257
KG K+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VDP K Y
Sbjct 4288 KGLKIKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKTY 4347
Query 4258 KDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPK 4317
DY+ GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+
Sbjct 4348 LDYIQQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDVD 4407
Query 4318 GFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSC 4360
G C L+GK+VQ+P DP+ + L + VC VCG W+ CSC
Sbjct 4408 GICKLRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSC 4449
Score = 83.2 bits (204), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 55/157 (35%), Positives = 80/157 (51%), Gaps = 2/157 (1%)
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
L +T NV DI+ A+ VIVN AN H+ HGGGVA A+ A KE+ +
Sbjct 1358 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1417
Query 1070 KLNGPLTVGGSCLLSGHNLAKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQDILLAPLL 1127
K G VG + +G L K L++VGP+ + + LL AY++ N+ D L+ L+
Sbjct 1418 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1477
Query 1128 SAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
SAGIF SL + V QV + N+K ++ +
Sbjct 1478 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDII 1514
Score = 78.2 bits (191), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 89/362 (25%), Positives = 158/362 (44%), Gaps = 48/362 (13%)
Query 616 LLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCV 675
LLGTT+ + + W L A W +L L+ G+F + + + I D
Sbjct 615 LLGTTL--VNKMVNWFNTMLDASAP--ATGW-LLYQLLNGLFVVSQANFNFVA-LIPDYA 668
Query 676 KCFIDVVNKALEMCIDQVTIAGAK----LRSLN-----LGEVFIAQSKGLYRQCIRGKEQ 726
K ++ ++ ++ VT+ K L+++N +G F S GL I G
Sbjct 669 KILVNKFYTFFKLLLECVTVDVLKDMPVLKTINGLVCIVGNKFYNVSTGL----IPG--- 721
Query 727 LQLLMPLKA-PKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSF---TNGAIVGTP 782
++P A +++ F EG +E V++++ +E +++ + S+ V
Sbjct 722 --FVLPCNAQEQQIYFFEG-------VAESVIVEDDVIENVKSSLSSYEYCQPPKSVEKI 772
Query 783 VCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGG--APIKG--VTFGED-TVWEVQGY 837
++ + + + DK P ++ N+ L P G V F E V E+
Sbjct 773 CIIDNMYMGKCGDK-----FFPIVMNDKNICLLDQAWRFPCAGRKVNFNEKPVVMEIPSL 827
Query 838 KNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD---LLTNM 894
V++ F+LD D +L + CS + VE G V +F VV +A+ L + + +
Sbjct 828 MTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCDAIENALNSCKEHPVVGYQV 887
Query 895 GIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTE 954
L++ + YLFD+AG+E +SRMYC+F D E+ +E E+ ID E +
Sbjct 888 RAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVISSEAVEDTIDGVVEDTINDD 947
Query 955 DD 956
+D
Sbjct 948 ED 949
Score = 43.1 bits (100), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 37/137 (27%), Positives = 60/137 (44%), Gaps = 14/137 (10%)
Query 1637 QVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSN 1696
+V GL S NC+L SVLL +Q+L KF A++ + + G +F +L
Sbjct 1147 KVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTTIP 1206
Query 1697 KTV--GELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYD 1754
K + + G V + L ++ + N C CG + L G++A+ + G +
Sbjct 1207 KAIVLPQGGFVADFAYWFLNQFDINAYA---NWCCLKCG-FSFDLNGLDALFFYGDI--- 1259
Query 1755 NLKTGVSIPCVCGRDAT 1771
VS C CG + T
Sbjct 1260 -----VSHVCKCGHNMT 1271
>sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus
512/2005 OX=693999 GN=1a PE=3 SV=1
Length=4128
Score = 1209 bits (3127), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 782/2261 (35%), Positives = 1215/2261 (54%), Gaps = 148/2261 (7%)
Query 2148 YVFTLLFQLCTFTKSTNSRIRASLPT---TIAKNSVKSVAKLCLDAGINYVKSPKFSKL- 2203
Y+F+LL K + ++ A +P I K SVK NY F +L
Sbjct 1984 YLFSLLAICFRALKKRDMKVMAGVPERTGIILKRSVK----------YNYKALKFFFRLK 2033
Query 2204 FTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSF 2263
F L S+ L +L + F + + G P C + Y NS+ D+C G+
Sbjct 2034 FQYIKVFLKFSLVLYTLYALMFMF-IRFTPVGTP-ICKRYTDGYANST-FDKNDYC-GNV 2089
Query 2264 PCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSA- 2322
C ICL G + L + I + L IL L +++ ++F FF +G++
Sbjct 2090 LCKICLYGYEELSDFTHTRVIWQHLKD-PLIGNILPLF--YLVFLIIFGGFFVRIGITYF 2146
Query 2323 IMQ-VFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGC 2381
IMQ + A + N WL+ + P ++M + + I H++ GC
Sbjct 2147 IMQYINAAGVALGYQDNVWLL-------HLLPFNSMGNIIVVAFIVTRILLFLKHVLFGC 2199
Query 2382 TSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTF 2441
+C+ C K + TRV TI+ G+ +SFYV ANGG+ FCK HN+ C++CD++ G TF
Sbjct 2200 DKPSCIACSKSAKLTRVPLQTILQGVTKSFYVNANGGKKFCKKHNFFCVDCDSYGYGCTF 2259
Query 2442 ISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNL 2501
I+D +A +LS K + PT ++ I+D V NG +LY K + +
Sbjct 2260 INDVIAPELSNVTKLNVIPTGPATIIIDKVEFSNGFYYLYSGSTFWKYNFDITEAKYACK 2319
Query 2502 DNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDST 2561
D L+ N + + +VF+ S + + K+A VY+SQL+C+PI L+D AL++ + +
Sbjct 2320 DVLKNCN----ILTDFVVFN-NSGSNVTQVKNACVYFSQLLCKPIKLVDSALLASL--NV 2372
Query 2562 EVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDT 2621
+ S + A+V+ S +F + + + R+ + +
Sbjct 2373 DFSANLHKAFVEVLSNSFGKDLSNCSNM----------------------NECRESLGLS 2410
Query 2622 DVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVE-NMTPRDLGACIDCNARHINAQV 2680
DV ++ + +H D+ ++ S NN +++Y K E + D+ C+ A+ +N V
Sbjct 2411 DVPEEEFSAAVSEAHRYDVLISDVSFNNLIVSYAKPEEKLAVHDIANCMRVGAKVVNHNV 2470
Query 2681 AKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGG 2740
NV ++W KD+++LSE+ RK I K I F LT R + + T ++ K G
Sbjct 2471 LTKDNVPVVWLAKDFIALSEEARKYIVRTTKTKGINFMLTFNDRRMHLTIPTISVANKKG 2530
Query 2741 KIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEI-IGYKAIQDGVTRDIIS 2799
+ + F + + L L+ + + L T++ +K I++GV +
Sbjct 2531 AGLPSLFTRLY--SFFWHLCVLIVVLFVATSLLDFSAQVTSDTQYDFKYIENGVLKVFEK 2588
Query 2800 TDDCFANKHAGFDAWFSQRGGSY-KNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDF 2858
DC N F+ W + + GS N + CP+V + E+ +I PG+P V + G
Sbjct 2589 PLDCVHNAFVNFNEWHNAKFGSIPTNSRRCPIVVGT-SDEVRYI-PGVPAGVF--LYGKS 2644
Query 2859 LHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEG 2918
L F +C+ L + +C+ + CT G+ V YCY +++
Sbjct 2645 LIFAMSTIFGTSGLCFDDRGLTD-----PDSCIFNSACTTLSGIGGRNV-YCYREGVVDN 2698
Query 2919 SISYSELRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDAEYCRHGTCERSEVGICLST 2977
+ YS L P + Y LMDG+ I P G +R + T YCR G C S+ G+C+
Sbjct 2699 AKLYSSLLPHSYYRLMDGNHIVLPEIITRGFGIRTIKTQAMTYCRTGECIDSQAGVCVGL 2758
Query 2978 SGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCA 3037
+V + S CG +L+ N+ + +S ++ ++A A
Sbjct 2759 DRFFVYSKT---PGSDYVCGTGFFSLLFNVIGMFSNSIPVTVMSGQILLNCVVAFTAVMA 2815
Query 3038 AYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYL-YLTFYF--T 3094
+ F KF+R+FG+ + V +S + +V S++ S+ L Y T YF T
Sbjct 2816 CFAFTKFKRLFGDMSFGV--------LSVGLCTVVNNLSYVVTQNSIGMLAYATLYFLCT 2867
Query 3095 NDV--SFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRV---MFNGVTF 3149
V S++ H+ + + + P+W+ Y+ C L+ F N + +V +F G F
Sbjct 2868 KGVRYSWVWHVGFAISYCFLAPWWVVLAYLICALLE----FLPNLFKLKVSTQLFEGDKF 2923
Query 3150 -STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAAC 3208
+FE AA TF+L+ Y KL + + + +Y A YN+YKY+SG+ YR A
Sbjct 2924 VGSFESAASGTFVLDMHSYQKLANS--ISTEKLKQYCASYNRYKYYSGSASEADYRLACF 2981
Query 3209 CHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLN 3268
HLAKA++DF+N D LY PP S S LQ+G RKMA PSG VEGC+V+V+ G TLN
Sbjct 2982 AHLAKAMSDFANDHMDKLYTPPTVSYNST-LQAGLRKMAQPSGIVEGCIVRVSYGNLTLN 3040
Query 3269 GLWLDDTVYCPRHVICT-AEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLL 3327
GLWL DTV CPRHVI + ++++ ++ L+R H+F + +GN+ L VI SM+ LL
Sbjct 3041 GLWLGDTVICPRHVIASNTTNVIDYDHAMSLVRL--HNFSISSGNMFLGVISASMRGTLL 3098
Query 3328 RLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGS 3387
+KV+ SN TP Y + ++PG +F++LACY+GS +GVY MR N+TI+GSF++G+CGS
Sbjct 3099 HIKVNQSNVNTPNYTYKVLKPGDSFNILACYDGSAAGVYGVNMRTNYTIRGSFISGACGS 3158
Query 3388 VGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAW 3447
G+NI+ V FCYMHH+EL +G H G+D++G YG + D+ T Q G +T NV +W
Sbjct 3159 PGYNINNGVVEFCYMHHLELGSGCHVGSDMDGTMYGKYEDQPTLQIEGASNLVTENVCSW 3218
Query 3448 LYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAA 3507
LY A+INGDRW+L+ + ++ +N A++ L +VD L A+TG+ V + A+
Sbjct 3219 LYGALINGDRWWLSSVSVGVDTYNEWALRNGMTAL--KNVDCFSLLVAKTGVDVGRLLAS 3276
Query 3508 LKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ-GKFKKIVKGTHHWMLLTFLT 3566
+++L N G++ILG T L DEFT +VV+Q GVT Q GK + + L FL
Sbjct 3277 IQKLHGN-FGGKSILGCTSLCDEFTLSEVVKQMYGVTLQSGKVSRAFRNASIVCCLLFL- 3334
Query 3567 SLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAY 3626
L + S F++ P L I+ ++ MLLVKHK FL L+LLPSL V+
Sbjct 3335 ---FLSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLFLQLYLLPSLCIVSG 3391
Query 3627 FNMV--YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARR 3684
+N+ Y ++++ + G+ + + + ++ L T R + +
Sbjct 3392 YNIFKDYHFYTYMLEEFDY----KVPFGGFNVTGVLNISLCCFVMGLHTFR--FLQTPNK 3445
Query 3685 VWT-LMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYY 3743
+++ ++ V+T++Y YY + + L+++ S + T F+ A +
Sbjct 3446 IFSYVVAVLTVLYTYYY------STDVLGLILTSMSGF----TNYWFIGTATYKLATYVL 3495
Query 3744 P--LLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMN 3801
P L + + ++ ++ +Y LGYC C Y+G +NR+ +LTLG Y++ VS EF+YM
Sbjct 3496 PHTSLLDSFDAIKAVVFLYLLLGYCNCVYYGSLYWINRFCKLTLGCYEFKVSAAEFKYMV 3555
Query 3802 SQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESS 3861
+ GL P DA L++KL+G+GG+ IK+++VQSK++D+KCT+VVLL L + + ++
Sbjct 3556 ANGLRAPTGVFDALILSLKLIGVGGRKTIKISSVQSKLTDLKCTNVVLLGCLSNMNIAAN 3615
Query 3862 SKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAI 3921
S+ WA CV LHN I L D A E +++LL+ LS A ++ L + ++ + LQ++
Sbjct 3616 SREWAYCVDLHNKINLCNDAEAAQEMLLALLAFFLSKNSAFGVDELLDSYFNDSSVLQSV 3675
Query 3922 ASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKM 3981
A+ + +LPSY AY TA+++YE A+ANG ++K+L+ ++NVAKSEFDR+A+ QRKL++M
Sbjct 3676 AATYVNLPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFDREASTQRKLDRM 3735
Query 3982 ADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPL 4041
A+QA +QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I++ A+DG VPL+IIP
Sbjct 3736 AEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLAKDGVVPLSIIPA 3795
Query 4042 TTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAW 4101
+A KL +VV D +Y YA +W + + D D K V E+ N +LAW
Sbjct 3796 VSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAKEVVTSNVESLAW 3855
Query 4102 PLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLAL 4161
PL + R +KLQNNE+ P ++Q A + D NAL Y+N G F+ A
Sbjct 3856 PLFLNCER---IIKLQNNEIIPSKIKQRPIKA-EGEGVVADGNAL--YSNEGGRTFMYAF 3909
Query 4162 LSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLG 4221
+SD DLK ++ G+ I ELEPPC+F+ + P GP VKYLYF++ LNNL RG VLG
Sbjct 3910 ISDKPDLKVVKWEFDGGSNAI--ELEPPCKFLVEAPSGPVVKYLYFVRNLNNLRRGAVLG 3967
Query 4222 SLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGT 4281
+ ATVRLQAG TE NS++L+ CAFAVDP K Y D + SG +P+ NCVKML +G
Sbjct 3968 FIGATVRLQAGKQTEQATNSSLLTLCAFAVDPPKTYLDAVKSGHRPVGNCVKMLANGSGN 4027
Query 4282 GQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFT 4341
GQAIT EA+ +Q+S+GGAS CLYCR H++HP+ GFC L+GKYVQ+P DP+ F
Sbjct 4028 GQAITNGVEASTNQDSYGGASVCLYCRAHVEHPDMDGFCKLRGKYVQVPLGTL-DPIRFV 4086
Query 4342 LRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCG 4382
L NTVC VCG W+ GC+CD+ ++QS D S +LN CG
Sbjct 4087 LENTVCKVCGCWQANGCTCDR---AVIQSVD-SGYLNE-CG 4122
Score = 69.7 bits (169), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 46/123 (37%), Positives = 60/123 (49%), Gaps = 2/123 (2%)
Query 1029 SANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL 1088
S N +VNAAN L HGGG+A AL+ T G +Q S+ Y+ NG + VG L+
Sbjct 1317 SVNHDFVVNAANEQLSHGGGIAKALDDLTKGELQVLSNQYVSRNGSIKVGSGVLIKCKE- 1375
Query 1089 AKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVR 1148
L+VVGP L KA F + + L PLLS GIF +SL + V
Sbjct 1376 -HSILNVVGPRKGKHAAELLTKAYTFVFKQKGVPLMPLLSVGIFKVPITESLAAFLACVG 1434
Query 1149 TQV 1151
+V
Sbjct 1435 DRV 1437
Score = 67.0 bits (162), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 77/317 (24%), Positives = 124/317 (39%), Gaps = 29/317 (9%)
Query 1538 SLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFV 1597
+L E K ++V T D + HT + S TYGQQ G ++ VT +KP + + V
Sbjct 1634 TLFEAKPVQVVVTQDQRSFHTVELSTSQTYGQQLGDCVVEDKKVTNLKPVSKDKVVS--V 1691
Query 1598 LPSDDTLRSEAF---EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLS 1654
+P+ D + F +HTLD + + +N G ++ +DNNC+++
Sbjct 1692 VPNVDWDKHYGFVDAGIFHTLDHTMFVFDNNVVN-----------GKRVLRTSDNNCWIN 1740
Query 1655 SVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQ 1714
+V L LQ KF LQ+ + GD A F + + GE D T+ + +
Sbjct 1741 AVCLQLQFANAKFKPKGLQQLWESYCTGDVAMFVHWLYWITGVEKGEPSDAENTLNIISR 1800
Query 1715 HANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIP-CVCGRDATQY 1773
+ + +L C +T + V+ ++ LK G+ CV G
Sbjct 1801 FLKPQGSVEMLRATSTTCDGTCST----KRVVSTPVVNASVLKVGLDDGNCVHGLPLVDR 1856
Query 1774 LVQQESSFVMMSA---PPAEYKLQQGTFLCANEYT----GNYQCGHYTHITAKETLYRID 1826
+V + ++ + P + L YT GHYT + KE D
Sbjct 1857 VVSVNGTVIITNVGDTPGKPVVATENLLLDGVSYTVFQDSTTGVGHYT-VFDKEAKLMFD 1915
Query 1827 GAHLTKMSEYKGPVTDV 1843
G L PVT V
Sbjct 1916 GDVLKPCDLNVSPVTSV 1932
>sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=1a PE=1 SV=1
Length=4117
Score = 1188 bits (3074), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 760/2185 (35%), Positives = 1153/2185 (53%), Gaps = 165/2185 (8%)
Query 2235 GAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETI---------- 2284
G+P C+ V Y NSS ++C S C +CL G L + + +
Sbjct 2050 GSP-VCDDVVAGYANSS-FDKNEYCN-SVICKVCLYGYQELSDFSHTQVVWQHLRDPLIG 2106
Query 2285 QVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWF 2344
V Y L I G +V A L+ F YL L VF G S +WF
Sbjct 2107 NVMPFFYLAFLAIFG--GVYVKAITLYFIFQYLNSLG----VFLGLQQS--------IWF 2152
Query 2345 IISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIV 2404
+ Q+ P + F + H+ GC ++C+ C K R RV TI
Sbjct 2153 L----QLVPFDVFGDEIVVFFIVTRVLMFIKHVCLGCDKASCVACSKSARLKRVPVQTIF 2208
Query 2405 NGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQS 2464
G +SFYV+ANGG FCK HN+ CLNCD++ G TFI+D +A ++ K + PT +
Sbjct 2209 QGTSKSFYVHANGGSKFCKKHNFFCLNCDSYGPGCTFINDVIATEVGNVVKLNVQPTGPA 2268
Query 2465 SYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKS 2524
+ ++D V NG +LY K S + + L+ S+ + IVF+
Sbjct 2269 TILIDKVEFSNGFYYLYSGDTFWKYNFDITDSKYTCKEALK----NCSIITDFIVFNNNG 2324
Query 2525 KCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPME 2584
+ + K+A VY+SQ++C+P+ L+D AL++ + S + + A+V S +F +
Sbjct 2325 S-NVNQVKNACVYFSQMLCKPVKLVDSALLASL--SVDFGASLHSAFVSVLSNSFGKDLS 2381
Query 2585 KLKALVATAHSELAKGVALDGV-LSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVT 2643
+ + + D V L TF +A + +H D+ +T
Sbjct 2382 SCNDM-----QDCKSTLGFDDVPLDTFNAAVAE------------------AHRYDVLLT 2418
Query 2644 GDSCNNFMLTYNKVENMTP-RDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQL 2702
S NNF +Y K E P D+ C+ A+ +N V ++ ++W V+D+++LSE+
Sbjct 2419 DMSFNNFTTSYAKPEEKFPVHDIATCMRVGAKIVNHNVLVKDSIPVVWLVRDFIALSEET 2478
Query 2703 RKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAAL 2762
RK I K I F LT R + T I+ K G + + K+ LC+
Sbjct 2479 RKYIIRTTKVKGITFMLTFNDCRMHTTIPTVCIANKKGAGLPSFSKVKKFFWFLCL---- 2534
Query 2763 VCYIVMPVHTLSIHDGYT----NEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQR 2818
+IV LS D T + +K I+ G + + C N FD W +
Sbjct 2535 --FIVAAFFALSFLDFSTQVSSDSDYDFKYIESGQLKTFDNPLSCVHNVFINFDQWHDAK 2592
Query 2819 GG-SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPS 2877
G + N+ SCP+V + + VPG+P V A G L F +C+ S
Sbjct 2593 FGFTPVNNPSCPIVVGV--SDEARTVPGIPAGVYLA--GKTLVFAINTIFGTSGLCFDAS 2648
Query 2878 KLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS 2937
+ + AC+ + CT +G YCY L+EG+ YSEL P + Y ++DG+
Sbjct 2649 GVAD-----KGACIFNSACTTLS-GLGGTAVYCYKNGLVEGAKLYSELAPHSYYKMVDGN 2702
Query 2938 IIQFPNTYLEG-SVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFC 2996
+ P G +R + T YCR G C +S G+C +V N E + S C
Sbjct 2703 AVSLPEIISRGFGIRTIRTKAMTYCRVGQCVQSAEGVCFGADRFFVYNAE---SGSDFVC 2759
Query 2997 GVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYN-HVV 3055
G L+ N+ + + V +S ++ IIA + + F KF+R+FG+ + V
Sbjct 2760 GTGLFTLLMNVISVFSKTVPVTVLSGQILFNCIIAFVAVAVCFLFTKFKRMFGDMSVGVF 2819
Query 3056 AANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYF--TNDVSFLA--HLQWFAMFSP 3111
A L + + + L Y T YF T V ++ HL + +
Sbjct 2820 TVGACTLLNNVSYIVTQNTLGMLG--------YATLYFLCTKGVRYMWIWHLGFLISYIL 2871
Query 3112 IVPFWITAIYVFCISLKHCHWFFNNYLRKRV---MFNGVTF-STFEEAALCTFLLNKEMY 3167
I P+W+ +Y F + F N + +V +F G F +FE AA TF+L+ Y
Sbjct 2872 IAPWWVLMVYAFSAIFE----FMPNLFKLKVSTQLFEGDKFVGSFENAAAGTFVLDMHAY 2927
Query 3168 LKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLY 3227
+L + + + +Y + YNKYKY+SG+ YR A HLAKA+ D++++ D LY
Sbjct 2928 ERLANS--ISTEKLRQYASTYNKYKYYSGSASEADYRLACFAHLAKAMMDYASNHNDTLY 2985
Query 3228 QPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAE 3287
PP S S LQ+G RKMA PSG VE C+V+V G LNGLWL D V CPRHVI ++
Sbjct 2986 TPPTVSYNST-LQAGLRKMAQPSGVVEKCIVRVCYGNMALNGLWLGDIVMCPRHVIASST 3044
Query 3288 -DMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRI 3346
++ +Y ++R H+F + +GNV L V+ +M+ LL++KV+ +N TPKY + +
Sbjct 3045 TSTIDYDYALSVLRL--HNFSISSGNVFLGVVSATMRGALLQIKVNQNNVHTPKYTYRTV 3102
Query 3347 QPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHME 3406
+PG++F++LACY+G+ +GVY MR N+TI+GSF+NG+CGS G+NI+ V FCY+H +E
Sbjct 3103 RPGESFNILACYDGAAAGVYGVNMRSNYTIRGSFINGACGSPGYNINNGTVEFCYLHQLE 3162
Query 3407 LPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTT 3466
L +G H G+DL+G YG + D+ T Q G + T NVLA+LYAA+ING W+L+
Sbjct 3163 LGSGCHVGSDLDGVMYGGYEDQPTLQVEGASSLFTENVLAFLYAALINGSTWWLSSSRIA 3222
Query 3467 LNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTI 3526
++ FN A+ T + D L+A+TG+ V + A+++ L +N G+ ILG T
Sbjct 3223 VDRFNEWAVHNGMT--TVGNTDCFSILAAKTGVDVQRLLASIQSLHKN-FGGKQILGHTS 3279
Query 3527 LEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWML----LTFLTSLLILVQSTQWSLFFF 3582
L DEFT +VVRQ GV QG + + + + +L LTF S L+ ++ FF+
Sbjct 3280 LTDEFTTGEVVRQMYGVNLQGGY--VSRACRNVLLVGSFLTFFWSELV-----SYTKFFW 3332
Query 3583 VYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMT 3642
V P + +++ M +KHK F +FL+P+L + N+ + +
Sbjct 3333 VNPGYVTPMFACLSLLSSLLMFTLKHKTLFFQVFLIPALIVTSCINLAF-------DVEV 3385
Query 3643 WLELAD-----TSLSGYRLKDCVMYASALVLLILMTART--VYDDAARRVWTLMNVITLV 3695
+ LA+ SL G+ + V V+ IL T ++ A V ++ ++T
Sbjct 3386 YNYLAEHFDYHVSLMGFNAQGLVNIFVCFVVTILHGTYTWRFFNTPASSVTYVVALLTAA 3445
Query 3696 YKVYYG-NALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQ 3754
Y +Y + L A++++A SVT N+ V + + + V++ + + + I G+ ++
Sbjct 3446 YNYFYASDILSCAMTLFA---SVTGNW--FVGAVCY--KVAVYMALRFPTFVAIFGD-IK 3497
Query 3755 CIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDA 3814
+M Y LGY CC++G+ NR+F++++GVYDY VS EF+YM + GL P ++D+
Sbjct 3498 SVMFCYLVLGYFTCCFYGILYWFNRFFKVSVGVYDYTVSAAEFKYMVANGLRAPTGTLDS 3557
Query 3815 FKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHND 3874
L+ KL+GIGG+ IK+++VQSK++D+KC++VVLL L + V ++S WA CV LHN
Sbjct 3558 LLLSAKLIGIGGERNIKISSVQSKLTDIKCSNVVLLGCLSSMNVSANSTEWAYCVDLHNK 3617
Query 3875 ILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAY 3934
I L D +A E +++LL+ LS A ++ L E ++ + LQ++AS + LPSY Y
Sbjct 3618 INLCNDPEKAQEMLLALLAFFLSKNSAFGLDDLLESYFNDNSMLQSVASTYVGLPSYVIY 3677
Query 3935 ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQAR 3994
A++ YE AV NG ++K+L+ ++NVAKSEFDR+A+ QRKL++MA+QA QMYK+AR
Sbjct 3678 ENARQQYEDAVNNGSPPQLVKQLRHAMNVAKSEFDREASTQRKLDRMAEQAAAQMYKEAR 3737
Query 3995 SEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDY 4054
+ ++++KV SAM ++LF MLR+LD +++ I+N A+DG VPL++IP +A KL +V D
Sbjct 3738 AVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNLAKDGVVPLSVIPAVSATKLNIVTSDI 3797
Query 4055 GTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAV 4114
+Y YA +W I + D D K+V + E+ N+ +L+WPL++ R V
Sbjct 3798 DSYNRIQREGCVHYAGTIWNIIDIKDNDGKVVHVKEVTAQNAESLSWPLVLGCER---IV 3854
Query 4115 KLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFP 4174
KLQNNE+ P L+Q S A A YNN G F+ A +SD DL+ ++
Sbjct 3855 KLQNNEIIPGKLKQRSIKAEGDGIV---GEGKALYNNEGGRTFMYAFISDKPDLRVVKWE 3911
Query 4175 KSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNA 4234
G TI ELEPP +F+ D+P G ++KYLYF++ LN L RG VLG + ATVRLQAG
Sbjct 3912 FDGGCNTI--ELEPPRKFLVDSPNGAQIKYLYFVRNLNTLRRGAVLGYIGATVRLQAGKQ 3969
Query 4235 TEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMD 4294
TE NS++L+ CAFAVDPAK Y D + SG +P+ NCVKML +G GQA+T EA+ +
Sbjct 3970 TEQAINSSLLTLCAFAVDPAKTYIDAVKSGHKPVGNCVKMLANGSGNGQAVTNGVEASTN 4029
Query 4295 QESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWK 4354
Q+S+GGAS CLYCR H++HP+ GFC LKGKYVQ+P DP+ F L N VC VCG W
Sbjct 4030 QDSYGGASVCLYCRAHVEHPSMDGFCRLKGKYVQVPLGTV-DPIRFVLENDVCKVCGCWL 4088
Query 4355 GYGCSCDQLREPLMQSADASTFLNR 4379
GC+CD+ +MQS D + +LN
Sbjct 4089 SNGCTCDR---SIMQSTDMA-YLNE 4109
Score = 87.4 bits (215), Expect = 6e-15, Method: Compositional matrix adjust.
Identities = 86/282 (30%), Positives = 133/282 (47%), Gaps = 29/282 (10%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLH 1094
+VNAAN L HGGG+A A++ T G +QK S+DYIK +GP+ VG +L L K +
Sbjct 1317 VVNAANEKLSHGGGIAKAIDVYTKGMLQKCSNDYIKAHGPIKVGRGVMLEA--LGLKVFN 1374
Query 1095 VVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGA---KPLQSLQVCVQTVRTQV 1151
VVGP L+KA F + + L PL+S GIF + L + CV +
Sbjct 1375 VVGPRKGKHAPELLVKAYKSVFANSGVALTPLISVGIFSVPLEESLSAFLACVGDRHCKC 1434
Query 1152 YIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPV--DVKP-KI 1208
+ DK + ++ Y+D L V+A +E +T + + + V QKPV + +P +I
Sbjct 1435 F-CYGDKE--REAIIKYMDGL---VDAIFKEALVDTTPVQEDVQQVSQKPVLPNFEPFRI 1488
Query 1209 KA------CIDEVTTTLEETKFL--TNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP 1260
+ C E +L K + TN L F + GK +D + E ++ +K
Sbjct 1489 EGAHAFYECNPEGLMSLGADKLVLFTNSNLDFCSV-GKCLNDVTSGALLEAINVFKKSNK 1547
Query 1261 YM-VGDVITSG-----DITCVVIPSKKAGGTTEMLSRALKKV 1296
+ G+ +T IT VV+P + +RA+ KV
Sbjct 1548 TVPAGNCVTLDCANMISITMVVLPFDGDANYDKNYARAVVKV 1589
Score = 51.2 bits (121), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 82/327 (25%), Positives = 131/327 (40%), Gaps = 37/327 (11%)
Query 1543 KTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
K++ + T D ++ V+ + TYGQQ GP ++ VT KP V V+P+ +
Sbjct 1631 KSVVIKVTEDTRSVKAVKVESTATYGQQIGPCLVNDTVVTDNKPVVADVVAK--VVPNAN 1688
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQ--VGGLTSIKWADNNCYLSSVLLAL 1660
++ ++ D++ G + L+HT + FP V G IK DNNC+++ L L
Sbjct 1689 ------WDSHYGFDKA--GEF-HMLDHTG-FTFPSEVVNGRRVIKTTDNNCWVNVTCLQL 1738
Query 1661 QQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQH---AN 1717
Q +F + LQ + GD A F + + G+ D + L ++ A
Sbjct 1739 QFARFRFKSAGLQAMWESYCTGDVAMFVHWLYWLTGVDKGQPSDSENALNMLSKYIVPAG 1798
Query 1718 LESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIP-CVCGRD-ATQYLV 1775
+ +RV + C C ++ T V A + LK GV C G + + +V
Sbjct 1799 SVTIERVTHDGC-CCSKRVVTAPVVNASV---------LKLGVEDGLCPHGLNYIGKVVV 1848
Query 1776 QQESSFVMMSAPPAEYKLQQGTFLCANEYT-----GNYQCGHYTHITAKETLYRIDGAHL 1830
+ ++ V+ P FL YT GN GHYT + DG
Sbjct 1849 VKGTTIVVNVGKPV--VAPSHLFLKGVSYTTFLDNGNGVVGHYTVFDHGTGMVH-DGDAF 1905
Query 1831 TKMSEYKGPVTDVFYKETSYTTTIKPV 1857
PVT+V E + PV
Sbjct 1906 VPGDLNVSPVTNVVVSEQTAVVIKDPV 1932
Score = 40.4 bits (93), Expect = 0.83, Method: Compositional matrix adjust.
Identities = 31/101 (31%), Positives = 49/101 (49%), Gaps = 8/101 (8%)
Query 1633 WKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALIL 1692
+ F GGL ++ + NNC+++S L+ LQ L + + PA+ E + R G C
Sbjct 1073 FDFVSYGGLKVLRQSHNNCWVTSTLVQLQLLGI-VDDPAM-ELFSAGRVGPMVRKC---Y 1127
Query 1693 AYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCG 1733
+G LGDV + L + +L + K +VVC CG
Sbjct 1128 ESQKAILGSLGDVSACLESLTK--DLHTLKITCSVVCG-CG 1165
>sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus
229E OX=11137 GN=1a PE=1 SV=1
Length=4085
Score = 1184 bits (3062), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 768/2269 (34%), Positives = 1180/2269 (52%), Gaps = 202/2269 (9%)
Query 2173 TTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAM-----WLLLLSICLGSLICVTAAF 2227
T + VK +AK G+ +S K++ + A+ WLL L LI +
Sbjct 1949 TAVTTGDVKIMAKAPQRTGVVLKRSLKYNLKASAAVLKSKWWLLAKFTKLLLLIYTLYSV 2008
Query 2228 GVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVT 2287
+L FG ++C+ Y S N D+C+GS C +CL G L + L+ +
Sbjct 2009 VLLCVRFGPFNFCSETVNGYAKS-NFVKDDYCDGSLGCKMCLFGYQELSQFSHLDVVWKH 2067
Query 2288 ISS--------YKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2339
I+ + + + +L ++ ++L+ ++ + + + VF GY ++
Sbjct 2068 ITDPLFSNMQPFIVMVLLLIFGDNYLRCFLLY----FVAQMISTVGVFLGYKETN----- 2118
Query 2340 WLMWFII--SIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATR 2397
W + FI I V+ +V I F H++ GC + C+ C K R R
Sbjct 2119 WFLHFIPFDVICDELLVTVIVIKVISFVR---------HVLFGCENPDCIACSKSARLKR 2169
Query 2398 VECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRP 2457
TIVNG++RSFYV ANGG FCK H + C++CD++ GSTFI+ EV+R+L K
Sbjct 2170 FPVNTIVNGVQRSFYVNANGGSKFCKKHRFFCVDCDSYGYGSTFITPEVSRELGNITKTN 2229
Query 2458 INPTDQSSYIVDSVAVKNGALHLY---------FDKAGQKTYERHPLSHFVNLDNLRANN 2508
+ PT + ++D V +NG LY FD K + + LD+ N
Sbjct 2230 VQPTGPAYVMIDKVEFENGFYRLYSCETFWRYNFDITESKYSCKEVFKNCNVLDDFIVFN 2289
Query 2509 TKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMF 2568
G+ + + K+ASVY+SQL+C+PI L+D L+S + S + + +
Sbjct 2290 NNGT--------------NVTQVKNASVYFSQLLCRPIKLVDSELLSTL--SVDFNGVLH 2333
Query 2569 DAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDV 2628
AY+D +F + L A ++ A + A G+++ F SA
Sbjct 2334 KAYIDVLRNSFG---KDLNANMSLAECKRALGLSISD--HEFTSAISN------------ 2376
Query 2629 IECLKLSHHSDLEVTGDSCNNFMLTYNK-VENMTPRDLGACIDCNARHINAQVAKSHNVS 2687
+H D+ ++ S NNF+ +Y K E ++ DL C+ A+ +NA V
Sbjct 2377 ------AHRCDVLLSDLSFNNFVSSYAKPEEKLSAYDLACCMRAGAKVVNANVLTKDQTP 2430
Query 2688 LIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLK--GGKIVST 2745
++W+ KD+ SLS + RK I +K + F LT + V + T I K G +
Sbjct 2431 IVWHAKDFNSLSAEGRKYIVKTSKAKGLTFLLTINENQAVTQIPATSIVAKQGAGDAGHS 2490
Query 2746 CFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFA 2805
L L L+C++ +C+ MP I + E +K I++G ++ + C
Sbjct 2491 LTWLWLLCGLVCLIQFYLCFF-MPYFMYDIVSSF--EGYDFKYIENGQLKNFEAPLKCVR 2547
Query 2806 NKHAGFDAW-FSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPR 2864
N F+ W +++ G + N +SCP+V + EI V G+P V + G L F +
Sbjct 2548 NVFENFEDWHYAKFGFTPLNKQSCPIVVGV--SEIVNTVAGIPSNVY--LVGKTLIFTLQ 2603
Query 2865 VFSAVGNICY------TPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEG 2918
+CY TP K C+ + CT + G V YCY+T L+EG
Sbjct 2604 AAFGNAGVCYDIFGVTTPEK-----------CIFTSACTRLEGLGGNNV-YCYNTALMEG 2651
Query 2919 SISYSELRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDAEYCRHGTCERSEVGICLST 2977
S+ YS ++ + Y +G+ I+ P +G R V T +YCR G C S G+C
Sbjct 2652 SLPYSSIQANAYYKYDNGNFIKLPEVIAQGFGFRTVRTIATKYCRVGECVESNAGVCFGF 2711
Query 2978 SGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCA 3037
+W +N+ R +G CG NL+ NI + +S ++ +
Sbjct 2712 D-KWFVNDG--RVANGYVCGTGLWNLVFNILSMFSSSFSVAAMSGQILLNCALGAFAIFC 2768
Query 3038 AYYFMKFRRVFGEYN----------------HVVAANALLFLMSFTILCLVPAYSFLPGV 3081
+ KFRR+FG+ + ++V N L+ ++++ IL Y F
Sbjct 2769 CFLVTKFRRMFGDLSVGVCTVVVAVLLNNVSYIVTQN-LVTMIAYAIL-----YFFATRS 2822
Query 3082 YSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKR 3141
+++ Y +SF P+W+ A Y L + L+ +
Sbjct 2823 LRYAWIWCAAYLIAYISF-------------APWWLCAWYF----LAMLTGLLPSLLKLK 2865
Query 3142 V---MFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGA 3197
V +F G F TFE AA TF+++ Y KL + ++ P + Y A YN+YKY+SG
Sbjct 2866 VSTNLFEGDKFVGTFESAAAGTFVIDMRSYEKL-ANSISP-EKLKSYAASYNRYKYYSGN 2923
Query 3198 LDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3257
+ YR A +LAKA+ DFS D+LY PP S S LQ+G RKMA PSG VE C+
Sbjct 2924 ANEADYRCACYAYLAKAMLDFSRDHNDILYTPPTVSYGST-LQAGLRKMAQPSGFVEKCV 2982
Query 3258 VQVTCGTTTLNGLWLDDTVYCPRHVICT-AEDMLNPNYEDLLIRKSNHSFLVQAGNVQLR 3316
V+V G T LNGLWL D VYCPRHVI + ++ ++E ++R H+F + +G L
Sbjct 2983 VRVCYGNTVLNGLWLGDIVYCPRHVIASNTTSAIDYDHEYSIMRL--HNFSIISGTAFLG 3040
Query 3317 VIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTI 3376
V+G +M L++KV +N TP++ F ++ G+ F++LACY+G GV+ MR N TI
Sbjct 3041 VVGATMHGVTLKIKVSQTNMHTPRHSFRTLKSGEGFNILACYDGCAQGVFGVNMRTNWTI 3100
Query 3377 KGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGT 3436
+GSF+NG+CGS G+N+ V F YMH +EL +G H G+ +G YG F D+ Q
Sbjct 3101 RGSFINGACGSPGYNLKNGEVEFVYMHQIELGSGSHVGSSFDGVMYGGFEDQPNLQVESA 3160
Query 3437 DTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQ 3496
+ +T+NV+A+LYAA++NG W+L + +N A + + + D L+A+
Sbjct 3161 NQMLTVNVVAFLYAAILNGCTWWLKGEKLFVEHYNEWAQANGFTAMNGE--DAFSILAAK 3218
Query 3497 TGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ-GKFKKIVKG 3555
TG+ V + A+ ++L NG G+ ILG + L DEF+ +VV+Q GV Q GK + K
Sbjct 3219 TGVCVERLLHAI-QVLNNGFGGKQILGYSSLNDEFSINEVVKQMFGVNLQSGKTTSMFKS 3277
Query 3556 THHWM-LLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLC 3614
+ + L + +T W V PF + ++A++ C +VKHK FL
Sbjct 3278 ISLFAGFFVMFWAELFVYTTTIW-----VNPGFLTPFMILLVALSLCLTFVVKHKVLFLQ 3332
Query 3615 LFLLPSLATVAYFNMVYMPASW---VMRIMTWLELADTSLSGYRLKDCVMYASALVLLIL 3671
+FLLPS+ A N +W V +++ + S+ ++ V L + +L
Sbjct 3333 VFLLPSIIVAAIQN-----CAWDYHVTKVLAEKFDYNVSVMQMDIQGFVNIFICLFVALL 3387
Query 3672 MTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFL 3731
T R + L ++I ++Y Y +S+ +++ SN + I +
Sbjct 3388 HTWRFAKERCTHWCTYLFSLIAVLYTALYSY---DYVSLLVMLLCAISNEWYIGAIIFRI 3444
Query 3732 AR-AIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDY 3790
R + F+ VEY + ++ ++L Y LG+ C Y+GL +NR+ + TLGVYD+
Sbjct 3445 CRFGVAFLPVEYVSYF----DGVKTVLLFYMLLGFVSCMYYGLLYWINRFCKCTLGVYDF 3500
Query 3791 LVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLL 3850
VS EF+YM + GL P DA L+ KL+GIGG IKV+TVQSK++D+KCT+VVL+
Sbjct 3501 CVSPAEFKYMVANGLNAPNGPFDALFLSFKLMGIGGPRTIKVSTVQSKLTDLKCTNVVLM 3560
Query 3851 SVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEE 3910
+L + + S+SK WA CV++HN I L D A E +++LL+ LS + L +
Sbjct 3561 GILSNMNIASNSKEWAYCVEMHNKINLCDDPETAQELLLALLAFFLSKHSDFGLGDLVDS 3620
Query 3911 MLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDR 3970
+N + LQ++AS F +PS+ AY TA++ YE AVANG S ++K+LKK++NVAK+EFDR
Sbjct 3621 YFENDSILQSVASSFVGMPSFVAYETARQEYENAVANGSSPQIIKQLKKAMNVAKAEFDR 3680
Query 3971 DAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNAR 4030
++++Q+K+ +MA+QA MYK+AR+ ++++KV SAM ++LF MLR+LD +++ I+N AR
Sbjct 3681 ESSVQKKINRMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNMAR 3740
Query 4031 DGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSE 4090
+G VPL++IP T+AA+L+VVVPD+ ++ YA +W +Q+V D D K V L +
Sbjct 3741 NGVVPLSVIPATSAARLVVVVPDHDSFVKMMVDGFVHYAGVVWTLQEVKDNDGKNVHLKD 3800
Query 4091 INMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN 4150
+ +N L WPLI+T R VKLQNNE+ P ++ + ++ NAL YN
Sbjct 3801 VTKENQEILVWPLILTCER---VVKLQNNEIMPGKMKVKATKGEGDGGITSEGNAL--YN 3855
Query 4151 NSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKG 4210
N G F+ A ++ +K+ ++ G T+ ELEPPCRFV DTP GP++KYLYF+K
Sbjct 3856 NEGGRAFMYAYVTTKPGMKYVKWEHDSGVVTV--ELEPPCRFVIDTPTGPQIKYLYFVKN 3913
Query 4211 LNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITN 4270
LNNL RG VLG + ATVRLQAG TE +NS +L+ C+FAVDPA AY D + G +P+ N
Sbjct 3914 LNNLRRGAVLGYIGATVRLQAGKQTEFVSNSHLLTHCSFAVDPAAAYLDAVKQGAKPVGN 3973
Query 4271 CVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIP 4330
CVKML +G+GQAIT T ++N Q+++GGAS C+YCR H+ HP GFC KGK+VQ+P
Sbjct 3974 CVKMLTNGSGSGQAITCTIDSNTTQDTYGGASVCIYCRAHVAHPTMDGFCQYKGKWVQVP 4033
Query 4331 TTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
NDP+ F L NTVC VCG W +GC+CD+ +QS D S +LN
Sbjct 4034 IG-TNDPIRFCLENTVCKVCGCWLNHGCTCDR---TAIQSFDNS-YLNE 4077
Score = 87.0 bits (214), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 66/196 (34%), Positives = 99/196 (51%), Gaps = 10/196 (5%)
Query 993 PEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGA 1052
P+ E +E +N F + DNVA D+ + IVNAAN +L HGGG+A A
Sbjct 1262 PKEEFVVKEKLNAFL----VHDNVAFYQGDVDTVVNGVDFDFIVNAANENLAHGGGLAKA 1317
Query 1053 LNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAA 1112
L+ T G +Q+ S ++I L G + VG ++ +L + +VVGP E L+KA
Sbjct 1318 LDVYTKGKLQRLSKEHIGLAGKVKVGTGVMVECDSL--RIFNVVGPRKGKHERDLLIKAY 1375
Query 1113 YENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT---QVYIAVNDKALYEQVVMDYL 1169
N Q L P+LS GIFG K SL+V + T +V++ + + + + L
Sbjct 1376 NTINNEQGTPLTPILSCGIFGIKLETSLEVLLDVCNTKEVKVFVYTDTEVCKVKDFVSGL 1435
Query 1170 DNLKPRVEAPKQEEPP 1185
N++ +VE PK E P
Sbjct 1436 VNVQ-KVEQPKIEPKP 1450
Score = 68.6 bits (166), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 84/340 (25%), Positives = 139/340 (41%), Gaps = 32/340 (9%)
Query 1537 LSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFF 1596
L E K I + T D N+H V ++ QQ G D++ P + +
Sbjct 1595 LKAAEAKVITIKVTEDGVNVHDVTVTTDKSFEQQVGVIADKDKDLSGAVPSDLNTSELLT 1654
Query 1597 VLPSDDTLRSEAFE---YYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYL 1653
D + F+ + T+D S Y SA+ V G+ +K +DNNC++
Sbjct 1655 KAIDVDWVEFYGFKDAVTFATVDHSAFA-YESAV----------VNGIRVLKTSDNNCWV 1703
Query 1654 SSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLL 1713
++V +ALQ + F + L A+ + GD F A + + G+ GD +T+T L
Sbjct 1704 NAVCIALQYSKPHFISQGLDAAWNKFVLGDVEIFVAFVYYVARLMKGDKGDAEDTLTKLS 1763
Query 1714 QH-ANLESAKRVLNVVCKHCGQK-TTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDAT 1771
++ AN + C C K ++ + + + ++ D ++ G CV G
Sbjct 1764 KYLANEAQVQLEHYSSCVECDAKFKNSVASINSAIVCASVKRDGVQVGY---CVHGIKYY 1820
Query 1772 QYLVQQESSFVMMSA----PPAEYKLQQGTFLCANEYTGNYQCGHYT-HITAKETLYRID 1826
+ +++S P A+ +L G A ++G GHYT + TAK+++Y D
Sbjct 1821 SRVRSVRGRAIIVSVEQLEPCAQSRLLSGVAYTA--FSGPVDKGHYTVYDTAKKSMY--D 1876
Query 1827 GAHLTKMSEYKGPVTDVF----YKETSYTTTIKPVSYKLD 1862
G K VT V Y T KPV +LD
Sbjct 1877 GDRFVKHDLSLLSVTSVVMVGGYVAPVNTVKPKPVINQLD 1916
Score = 49.7 bits (117), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 61/266 (23%), Positives = 109/266 (41%), Gaps = 20/266 (8%)
Query 1635 FPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAY 1694
F ++ GL +K DNNC+++SV+L +Q + A+Q + G A
Sbjct 1038 FEELNGLKILKQLDNNCWVNSVMLQIQLTGILDGDYAMQ----FFKMGRVAKMIERCYTA 1093
Query 1695 SNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYD 1754
G +GDV M LL+ +L + V++ C C +G AV++ T +
Sbjct 1094 EQCIRGAMGDVGLCMYRLLK--DLHTGFMVMDYKCS-CTSGRLEESG--AVLFC-TPTKK 1147
Query 1755 NLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHY- 1813
G + C R T +Q FV P +C++ + G CGHY
Sbjct 1148 AFPYGTCLNCNAPRMCTIRQLQGTIIFVQQKPEPVNPVSFVVKPVCSSIFRGAVSCGHYQ 1207
Query 1814 THITAKETLYRIDGAHLTKMSEYKG-PVTDVFYKETSYTT----TIKPVSYKLDGVTYTE 1868
T+I ++ +DG + K+ + + + K+ Y ++ P+ +D E
Sbjct 1208 TNIYSQNLC--VDGFGVNKIQPWTNDALNTICIKDADYNAKVEISVTPIKNTVDTTPKEE 1265
Query 1869 --IEPKLDGYYKKDNAYYTEQPIDLV 1892
++ KL+ + DN + + +D V
Sbjct 1266 FVVKEKLNAFLVHDNVAFYQGDVDTV 1291
>sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus
NL63 OX=277944 GN=1a PE=1 SV=1
Length=4060
Score = 1176 bits (3043), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 788/2331 (34%), Positives = 1205/2331 (52%), Gaps = 183/2331 (8%)
Query 2096 LKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQ 2155
L T+A I + S + P + I+ + AQ+ F + +V +
Sbjct 1858 LSTLAVTAIVVVGGCVTSNV-----PTIVSEKISVMDKLDTGAQKFFQ-FGDFVMNNIVL 1911
Query 2156 LCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKF---SKLFTIAM-WLL 2211
T+ S S +R T+I K+ +K +AK G+ +S K+ S LF I W +
Sbjct 1912 FLTWLLSMFSLLR----TSIMKHDIKVIAKAPKRTGVILTRSFKYNIRSALFVIKQKWCV 1967
Query 2212 LLSICLGSLICVTAAFGVLLSNFGAPS---YCNGVRELYLNSSNVTTMDFCEGSFPCSIC 2268
++++ L+ V + +P C + Y S +C S C +C
Sbjct 1968 IVTLFKFLLLLYAIYALVFMIVQFSPFNSLLCGDIVSGY-EKSTFNKDIYCGNSMVCKMC 2026
Query 2269 LSGLDSLDSYPALETIQVTISSYK--LDLTILGLAAEWVLAYML-FTKFFYLLGLSAIMQ 2325
L SY + T +K D ++ L +L +L F + GL +
Sbjct 2027 LF------SYQEFNDLDHTSLVWKHIRDPILISLQPFVILVILLIFGNMYLRFGLLYFVA 2080
Query 2326 VFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYY--IWKSYVHIMDGCTS 2383
F F S F+ WF+ P + F A+F I HI+ GC +
Sbjct 2081 QFISTFGS-FLGFHQKQWFL----HFVPFDVLCNE--FLATFIVCKIVLFVRHIIVGCNN 2133
Query 2384 STCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFIS 2443
+ C+ C K R RV TI+NGM +SFYV ANGG FC HN+ C+NCD+F G+TFI+
Sbjct 2134 ADCVACSKSARLKRVPLQTIINGMHKSFYVNANGGTCFCNKHNFFCVNCDSFGPGNTFIN 2193
Query 2444 DEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLY---------FDKAGQKTYERHP 2494
++AR+L K + PT + I+D V NG LY FD K +
Sbjct 2194 GDIARELGNVVKTAVQPTAPAYVIIDKVDFVNGFYRLYSGDTFWRYDFDITESKYSCKEV 2253
Query 2495 LSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALV 2554
L + L+N N GS + + K+A VY+SQL+C+PI L++ L+
Sbjct 2254 LKNCNVLENFIVYNNSGS--------------NITQIKNACVYFSQLLCEPIKLVNSELL 2299
Query 2555 SDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAA 2614
S + S + + + AYVD +F ++L A ++ A + G+
Sbjct 2300 STL--SVDFNGVLHKAYVDVLCNSF---FKELTANMSMAECKATLGLT------------ 2342
Query 2615 RQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVEN-MTPRDLGACIDCNA 2673
V D + + +H D+ ++ S NNF ++Y K E+ ++ D+ C+ +
Sbjct 2343 --------VSDDDFVSAVANAHRYDVLLSDLSFNNFFISYAKPEDKLSVYDIACCMRAGS 2394
Query 2674 RHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITT 2733
+ +N V ++ ++W VKD+ +LS++ +K + K + F LT + + V T
Sbjct 2395 KVVNHNVLIKESIPIVWGVKDFNTLSQEGKKYLVKTTKAKGLTFLLTFNDNQAITQVPAT 2454
Query 2734 KISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGV 2793
I K G + + L V + + T++ GY +K I++G
Sbjct 2455 SIVAKQGAGFKRTYNFLWYVCLFVVALFIGVSFIDYTTTVTSFHGYD-----FKYIENGQ 2509
Query 2794 TRDIISTDDCFANKHAGFDAWFSQRGGSYK-NDKSCPVVAAIITREIGFIVPGLPGTVLR 2852
+ + C N F+ W + G N CP+V + R +VPG+P V
Sbjct 2510 LKVFEAPLHCVRNVFDNFNQWHEAKFGVVTTNSDKCPIVVGVSERIN--VVPGVPTNVY- 2566
Query 2853 AINGDFLHFLPRVFSAVGN--ICYTPSKLIEYSDFATS-ACVLAAECTIFKDAMGKPVPY 2909
+ G L F + +A GN +CY ++ TS C+ + CT + G V Y
Sbjct 2567 -LVGKTLVFTLQ--AAFGNTGVCY------DFDGVTTSDKCIFNSACTRLEGLGGDNV-Y 2616
Query 2910 CYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDAEYCRHGTCER 2968
CY+T+L+EGS YS L+P+ Y + ++FP G +R + T YCR G C
Sbjct 2617 CYNTDLIEGSKPYSTLQPNAYYKYDAKNYVRFPEILARGFGLRTIRTLATRYCRVGECRD 2676
Query 2969 SEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGG 3028
S G+C +W +N+ R G CG ++L+ N+ + + +S ++
Sbjct 2677 SHKGVCFGFD-KWYVNDG--RVDDGYICGDGLIDLLVNVLSIFSSSFSVVAMSGHMLFNF 2733
Query 3029 IIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILC--LVPAYSFLPG---VYS 3083
+ A +T + KF+RVFG+ ++ V FT++C L+ S++ +
Sbjct 2734 LFAAFITFLCFLVTKFKRVFGDLSYGV----------FTVVCATLINNISYVVTQNLFFM 2783
Query 3084 VFYLYLTFYFTNDV--SFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKR 3141
+ Y L F FT V +++ H+ + + ++P+W+ + F L+ N + +
Sbjct 2784 LLYAILYFVFTRTVRYAWIWHIAYIVAYFLLIPWWLLTWFSFAAFLE----LLPNVFKLK 2839
Query 3142 V---MFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGA 3197
+ +F G F TFE AA TF+L+ Y +L + T+ P + Y A YNKYKY+SG+
Sbjct 2840 ISTQLFEGDKFIGTFESAAAGTFVLDMRSYERLIN-TISP-EKLKNYAASYNKYKYYSGS 2897
Query 3198 LDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3257
YR A HLAKA+ D++ D+LY PP S S LQSG +KMA PSG VE C+
Sbjct 2898 ASEADYRCACYAHLAKAMLDYAKDHNDMLYSPPTISYNST-LQSGLKKMAQPSGCVERCV 2956
Query 3258 VQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRV 3317
V+V G+T LNG+WL DTV CPRHVI + +L +Y+ H+F V V L V
Sbjct 2957 VRVCYGSTVLNGVWLGDTVTCPRHVIAPSTTVL-IDYDHAYSTMRLHNFSVSHNGVFLGV 3015
Query 3318 IGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIK 3377
+G +M +LR+KV SN TPK+ F ++PG +F++LACY G SGV+ +R N TIK
Sbjct 3016 VGVTMHGSVLRIKVSQSNVHTPKHVFKTLKPGDSFNILACYEGIASGVFGVNLRTNFTIK 3075
Query 3378 GSFLNGSCGSVGFNIDYD-CVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGT 3436
GSF+NG+CGS G+N+ D V FCY+H +EL +G H G+D G YG F D+ + Q
Sbjct 3076 GSFINGACGSPGYNVRNDGTVEFCYLHQIELGSGAHVGSDFTGSVYGNFDDQPSLQVESA 3135
Query 3437 DTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQ 3496
+ ++ NV+A+LYAA++NG RW+L ++ FN AM Y ++ V+ L+A+
Sbjct 3136 NLMLSDNVVAFLYAALLNGCRWWLCSTRVNVDGFNEWAMANGYTSVSS--VECYSILAAK 3193
Query 3497 TGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGT 3556
TG++V + A+++ L G G+ ILG + L DEFT +VV+Q GV Q K++ G
Sbjct 3194 TGVSVEQLLASIQHL-HEGFGGKNILGYSSLCDEFTLAEVVKQMYGVNLQSG--KVIFGL 3250
Query 3557 HHWMLLTFLTSLLILVQSTQWSLFFFVYENA-------FLPFTLGIMAIAACAMLLVKHK 3609
L + ++ W+ F +Y N P ++ ++ + +KHK
Sbjct 3251 KTMFLFSVFFTMF-------WAELF-IYTNTIWINPVILTPIFCLLLFLSLVLTMFLKHK 3302
Query 3610 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLL 3669
FL +FLLP++ A +N V ++++ + + S+ ++ V L ++
Sbjct 3303 FLFLQVFLLPTVIATALYNCVL--DYYIVKFLADHFNYNVSVLQMDVQGLVNVLVCLFVV 3360
Query 3670 ILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIM 3729
L T R + + ++I + Y +Y + M+ IS + Y G + +
Sbjct 3361 FLHTWRFSKERFTHWFTYVCSLIAVAYTYFYSGDFLSLLVMFLCAIS-SDWYIGAI--VF 3417
Query 3730 FLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYD 3789
L+R IVF E +F ++ ++VY GY C Y+G+ NR+F+ T+GVYD
Sbjct 3418 RLSRLIVFFSPES---VFSVFGDVKLTLVVYLICGYLVCTYWGILYWFNRFFKCTMGVYD 3474
Query 3790 YLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVL 3849
+ VS EF+YM + GL P DA L+ KLLGIGG CIK++TVQSK++D+KCT+VVL
Sbjct 3475 FKVSAAEFKYMVANGLHAPHGPFDALWLSFKLLGIGGDRCIKISTVQSKLTDLKCTNVVL 3534
Query 3850 LSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCE 3909
L L + + ++S WA CV LHN I L D +A +++LL+ LS ++ L +
Sbjct 3535 LGCLSSMNIAANSSEWAYCVDLHNKINLCDDPEKAQSMLLALLAFFLSKHSDFGLDGLID 3594
Query 3910 EMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFD 3969
DN +TLQ++AS F S+PSY AY A++AYE A+ANG S ++K+LK+++N+AKSEFD
Sbjct 3595 SYFDNSSTLQSVASSFVSMPSYIAYENARQAYEDAIANGSSSQLIKQLKRAMNIAKSEFD 3654
Query 3970 RDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNA 4029
+ ++Q+K+ +MA+QA TQMYK+ARS ++++KV SAM ++LF MLR+LD ++ ++N A
Sbjct 3655 HEISVQKKINRMAEQAATQMYKEARSVNRKSKVISAMHSLLFGMLRRLDMSSVETVLNLA 3714
Query 4030 RDGCVPLNIIPLTTAAKLMVVVPDYGTY-KNTCDGNTFTYASALWEIQQVVDADSKIVQL 4088
RDG VPL++IP T+A+KL +V PD +Y K CDG+ YA +W + V D D + V +
Sbjct 3715 RDGVVPLSVIPATSASKLTIVSPDLESYSKIVCDGSV-HYAGVVWTLNDVKDNDGRPVHV 3773
Query 4089 SEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAY 4148
EI +N L WPLI+ R VKLQNNE+ P L+Q A D NAL
Sbjct 3774 KEITKENVETLTWPLILNCER---VVKLQNNEIMPGKLKQKPMKAEGDGGVLGDGNAL-- 3828
Query 4149 YNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFI 4208
YN G F+ A +S+ DLK+ ++ G TI EL+ PCRF+ +TP GP+VKYLYF+
Sbjct 3829 YNTEGGKTFMYAYISNKADLKFVKWEYEGGCNTI--ELDSPCRFMVETPNGPQVKYLYFV 3886
Query 4209 KGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPI 4268
K LN L RG VLG + AT+RLQAG TE+ NS +L+ CAF+VDPA Y + + G +P+
Sbjct 3887 KNLNTLRRGAVLGFIGATIRLQAGKQTELAVNSGLLTACAFSVDPATTYLEAVKHGAKPV 3946
Query 4269 TNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQ 4328
+NC+KML G GQAIT + +AN +Q+S+GGAS CLYCR H+ HP+ G+C KGK VQ
Sbjct 3947 SNCIKMLSNGAGNGQAITTSVDANTNQDSYGGASICLYCRAHVPHPSMDGYCKFKGKCVQ 4006
Query 4329 IPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
+P C DP+ F L N VC VCG W G+GC+CD+ +QS D S +LN
Sbjct 4007 VPIGCL-DPIRFCLENNVCNVCGCWLGHGCACDR---TTIQSVDIS-YLNE 4052
Score = 84.0 bits (206), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 58/159 (36%), Positives = 81/159 (51%), Gaps = 10/159 (6%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLH 1094
+VNAAN +L HGGGVA A++ T G +Q S DYI NGPL VG +L +
Sbjct 1285 VVNAANENLLHGGGVARAIDILTEGQLQSLSKDYISSNGPLKVGAGVMLECEKF--NVFN 1342
Query 1095 VVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAK---PLQSLQVCVQTVRTQV 1151
VVGP E L++A I L PLLS GIFG + L++L C QV
Sbjct 1343 VVGPRTGKHEHSLLVEAYNSILFENGIPLMPLLSCGIFGVRIENSLKALFSCDINKPLQV 1402
Query 1152 YIAVNDKALYEQVVMDYLD--NLKPRVEAPKQEEPPNTE 1188
++ +++ EQ V+ +LD +L P ++ +P E
Sbjct 1403 FVYSSNE---EQAVLKFLDGLDLTPVIDDVDVVKPFRVE 1438
Score = 53.1 bits (126), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 72/288 (25%), Positives = 119/288 (41%), Gaps = 28/288 (10%)
Query 1550 TVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLP-SDDTLRSEA 1608
T D N+ +V+ S + G+Q G DG D + EG VLP + DT+ S A
Sbjct 1587 TEDGINVKDVVVESSKSLGKQLGVVS-DGVD--------SFEG----VLPINTDTVLSVA 1633
Query 1609 FEYYHTLDESFLGRYMSALNHTKKWKFPQ--VGGLTSIKWADNNCYLSSVLLALQQLEVK 1666
E F + A K + +P VGG + DNNC++++ + LQ L+
Sbjct 1634 PEVDWVAFYGFEKAALFASLDVKPYGYPNDFVGGFRVLGTTDNNCWVNATCIILQYLKPT 1693
Query 1667 FNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLN 1726
F + L + + GD F + I + + G+ GD E ++ L ++ L S V
Sbjct 1694 FKSKGLNVLWNKFVTGDVGPFVSFIYFITMSSKGQKGDAEEALSKLSEY--LISDSIVTL 1751
Query 1727 VVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSA 1786
C +T+ V++ + ++ LK G + R + V+ + V+++
Sbjct 1752 EQYSTCDICKSTVVEVKSAIVCASV----LKDGCDVGFCPHRHKLRSRVKFVNGRVVITN 1807
Query 1787 PPAEYKLQQGTFLCANEYT---GNYQCGHY-THITAKETLYRIDGAHL 1830
Q L YT G++ GHY + A +Y DGA L
Sbjct 1808 VGEPIISQPSKLLNGIAYTTFSGSFDNGHYVVYDAANNAVY--DGARL 1853
>sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=1a PE=1 SV=1
Length=4017
Score = 1117 bits (2888), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 726/2197 (33%), Positives = 1116/2197 (51%), Gaps = 158/2197 (7%)
Query 2240 CNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILG 2299
CNG + Y NSS + + C S C CL+ D L + + +QVT +K D
Sbjct 1921 CNGAVQAYKNSSFIKSA-VCGNSILCKACLASYDELADF---QHLQVTWD-FKSDPLWNR 1975
Query 2300 LAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWF-------IISIVQMA 2352
L L+Y F F + ++ F YF S ++ N WL +F + +V
Sbjct 1976 LVQ---LSYFAFLAVFG----NNYVRCFLMYFVSQYL-NLWLSYFGYVEYSWFLHVVNFE 2027
Query 2353 PVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFY 2412
+SA + + K HI+ C++ +C C + R TR+ +VNG ++ Y
Sbjct 2028 SISAEFVIVVIVVKAVLALK---HIVFACSNPSCKTCSRTARQTRIPIQVVVNGSMKTVY 2084
Query 2413 VYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVA 2472
V+ANG FCK HN+ C NCD++ +TFI DE+ RDLS K+ + TD+S V V
Sbjct 2085 VHANGTGKFCKKHNFYCKNCDSYGFENTFICDEIVRDLSNSVKQTVYATDRSHQEVTKVE 2144
Query 2473 VKNGALHLY---------FDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGK 2523
+G Y +D +K + L + LD+ + GS NV
Sbjct 2145 CSDGFYRFYVGDEFTSYDYDVKHKKYSSQEVLKSMLLLDDFIVYSPSGSALANV------ 2198
Query 2524 SKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPM 2583
++A VY+SQL+ +PI +++ L+ D+ S + +F+A + +F+V +
Sbjct 2199 --------RNACVYFSQLIGKPIKIVNSDLLEDL--SVDFKGALFNAKKNVIKNSFNVDV 2248
Query 2584 EKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVT 2643
+ K L E + L+ STF A +H + +T
Sbjct 2249 SECKNL-----DECYRACNLNVSFSTFEMAVNN------------------AHRFGILIT 2285
Query 2644 GDSCNNFMLTYNK--VENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQ 2701
S NNF + K ++ D+G C+ +A+ +NA+V S++W +D+ +LS
Sbjct 2286 DRSFNNFWPSKVKPGSSGVSAMDIGKCMTSDAKIVNAKVLTQRGKSVVWLSQDFAALSST 2345
Query 2702 LRKQIRSAAKKNNIPFRLTCATTRQVVNV----ITTKISLKGGKIVSTCFKLMLKATLLC 2757
+K + + + F LT ++ T +S K G + + +L
Sbjct 2346 AQKVLVKTFVEEGVNFSLTFNAVGSDDDLPYERFTESVSPKSGSGFFDVITQLKQIVILV 2405
Query 2758 VLAALVC-----YIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFD 2812
+ +C Y V + +GY Y I++G+ + T C N + GF
Sbjct 2406 FVFIFICGLCSVYSVATQSYIESAEGYD-----YMVIKNGIVQPFDDTISCVHNTYKGFG 2460
Query 2813 AWFSQRGGSYKN-DKSCP-VVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVG 2870
WF + G KSCP VV + E +P +P V +I G L F V
Sbjct 2461 DWFKAKYGFIPTFGKSCPIVVGTVFDLENMRPIPDVPAYV--SIVGRSLVFAINAAFGVT 2518
Query 2871 NICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTR 2930
N+CY + D CV CT +G + YC L+EG+ YS+L PD
Sbjct 2519 NMCYDHTGNAVSKDSYFDTCVFNTACTTLT-GLGGTIVYCAKQGLVEGAKLYSDLMPDYY 2577
Query 2931 YVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRA 2990
Y G++++ P +R V T YCR G C S+ G C +V +NE
Sbjct 2578 YEHASGNMVKLPAIIRGLGLRFVKTQATTYCRVGECIDSKAGFCFGGDNWFVYDNEFG-- 2635
Query 2991 LSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGE 3050
+G CG + N+F + + S +++ IIA L Y +KF+++FG+
Sbjct 2636 -NGYICGNSVLGFFKNVFKLFNSNMSVVATSGAMLVNIIIACLAIAMCYGVLKFKKIFGD 2694
Query 3051 YNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQ--WFAM 3108
++ ++ L+ + V +F +Y++ Y ++ T +++ L +
Sbjct 2695 CTFLIVM-IIVTLVVNNVSYFVTQNTFFMIIYAIVY----YFITRKLAYPGILDAGFIIA 2749
Query 3109 FSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMY 3167
+ + P+++ Y+ F + +F G F FE AA+ TF+++ Y
Sbjct 2750 YINMAPWYVITAYILVFLYDSLPSLFKLKVSTN-LFEGDKFVGNFESAAMGTFVIDMRSY 2808
Query 3168 LKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLY 3227
+ + T + + Y +NKYKY++G++ YR A HL KAL D+S + D+LY
Sbjct 2809 ETIVNST--SIARIKSYANSFNKYKYYTGSMGEADYRMACYAHLGKALMDYSVNRTDMLY 2866
Query 3228 QPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAE 3287
PP S+ S LQSG RKMA PSG VE C+V+V+ G LNGLWL D V CPRHVI +
Sbjct 2867 TPPTVSVNST-LQSGLRKMAQPSGLVEPCIVRVSYGNNVLNGLWLGDEVICPRHVIASDT 2925
Query 3288 DMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQ 3347
+ NYE+ + H+F V NV L V+ + L LKV+ NP TP++KF I+
Sbjct 2926 TRV-INYENEMSSVRLHNFSVSKNNVFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIK 2984
Query 3348 PGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMEL 3407
G++F++LACY G P VY MR TIKGSF+ G+CGSVG+ ++ + F YMHH+EL
Sbjct 2985 AGESFNILACYEGCPGSVYGVNMRSQGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLEL 3044
Query 3408 PTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTL 3467
G H G++ EG+ YG + D+ + Q GT+ + NV+A+LYAA+ING+RWF+ + +L
Sbjct 3045 GNGSHVGSNFEGEMYGGYEDQPSMQLEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSL 3104
Query 3468 NDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTIL 3527
+N A ++ L+ D L+A+TG +V + ++ L G GRTIL L
Sbjct 3105 ESYNTWAKTNSFTELSS--TDAFSMLAAKTGQSVEKLLDSIVRL-NKGFGGRTILSYGSL 3161
Query 3528 EDEFTPFDVVRQCSGVTFQ-GKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFF----F 3582
DEFTP +V+RQ GV Q GK K + + ++T +T L W FF F
Sbjct 3162 CDEFTPTEVIRQMYGVNLQAGKVK-----SFFYPIMTAMTILFAF-----WLEFFMYTPF 3211
Query 3583 VYEN-AFLPFTLGIMAIAACAMLL-VKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRI 3640
+ N F+ L + + + + +KHK F F+LPS+ V N+ + S+ +
Sbjct 3212 TWINPTFVSIVLAVTTLISTVFVSGIKHKMLFFMSFVLPSVILVTAHNL-FWDFSYYESL 3270
Query 3641 MTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVY---K 3697
+ +E +T ++ ++ ++ + + R ++ W + V T++
Sbjct 3271 QSIVENTNTMFLPVDMQGVMLTVFCFIVFVTYSVRFF---TCKQSWFSLAVTTILVIFNM 3327
Query 3698 VYYGNALDQA----------ISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLF 3747
V D+ ++M +++S+T+ VV +A IV VCV P F
Sbjct 3328 VKIFGTSDEPWTENQIAFCFVNMLTMIVSLTTKDWMVVIASYRIAYYIV-VCV--MPSAF 3384
Query 3748 ITG-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLL 3806
++ ++CI +VY GY CCY+G+ +NR+ +T GVY + VS E +YM + L
Sbjct 3385 VSDFGFMKCISIVYMACGYLFCCYYGILYWVNRFTCMTCGVYQFTVSAAELKYMTANNLS 3444
Query 3807 PPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWA 3866
PK++ DA L+ KL+G+GGK IK++TVQSK++++KCT+VVLL +L ++ VES+SK W
Sbjct 3445 APKNAYDAMILSAKLIGVGGKRNIKISTVQSKLTEMKCTNVVLLGLLSKMHVESNSKEWN 3504
Query 3867 QCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFS 3926
CV LHN+I L D EK+++L++ LS D++ L E +N LQ++AS ++
Sbjct 3505 YCVGLHNEINLCDDPEIVLEKLLALIAFFLSKHNTCDLSELIESYFENTTILQSVASAYA 3564
Query 3927 SLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAM 3986
+LPS+ A A+ E+A N S +LK+L K+ N+AKS+F+R+A++Q+KL+KMA+QA
Sbjct 3565 ALPSWIALEKARADLEEAKKNDVSPQILKQLTKAFNIAKSDFEREASVQKKLDKMAEQAA 3624
Query 3987 TQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAK 4046
MYK+AR+ D+++K+ SAM ++LF ML+KLD ++N II+ AR+G +PL+IIP +A +
Sbjct 3625 ASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSVNTIIDQARNGVLPLSIIPAASATR 3684
Query 4047 LMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVT 4106
L+V+ P + N YA A+W I +V DA+ V L E+ N NL WPL +T
Sbjct 3685 LVVITPSLEVFSKIRQENNVHYAGAIWTIVEVKDANGSHVHLKEVTAANELNLTWPLSIT 3744
Query 4107 ALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQ 4166
R KLQNNE+ P L++ + A T + A + G F+ A ++
Sbjct 3745 CERTT---KLQNNEIMPGKLKERAVRASATLDGEAFGSGKALMASESGKSFMYAFIASDN 3801
Query 4167 DLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAAT 4226
+LK+ ++ ++ I ELE P RF D GP+VKYLYF+K LN L RG VLG + AT
Sbjct 3802 NLKYVKWESNN--DIIPIELEAPLRFYVDGANGPEVKYLYFVKNLNTLRRGAVLGYIGAT 3859
Query 4227 VRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAIT 4286
VRLQAG TE P+NS++L+ CAF+ DPAKAY D + G QP+ NCVKML G G A+T
Sbjct 3860 VRLQAGKPTEHPSNSSLLTLCAFSPDPAKAYVDAVKRGMQPVNNCVKMLSNGAGNGMAVT 3919
Query 4287 VTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTV 4346
EAN Q+S+GGAS C+YCRCH++HP G C KGK+VQIPT DP+ F + N V
Sbjct 3920 NGVEANTQQDSYGGASVCIYCRCHVEHPAIDGLCRYKGKFVQIPTG-TQDPIRFCIENEV 3978
Query 4347 CTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGV 4383
C VCG W GC CD R + ++LN CGV
Sbjct 3979 CVVCGCWLNNGCMCD--RTSMQSFTVDQSYLNE-CGV 4012
Score = 65.5 bits (158), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 72/276 (26%), Positives = 118/276 (43%), Gaps = 28/276 (10%)
Query 969 ETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQF--TGYLKLTDNVAIKCVDIVKE 1026
+ +VE+ E++ +++ E E P ++ + F G L ++ ++
Sbjct 1288 QEFKVEKVEQQPIVEENKSSIEKEEIQSPKNDDLILPFYKAGKLSFYQGALDVLINFLE- 1346
Query 1027 AQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGH 1086
P VIVNAAN LKH GGVA A++ T G + + S DY+K N + G +
Sbjct 1347 -----PDVIVNAANGDLKHMGGVARAIDVFTGGKLTERSKDYLKKNKSIAPGNAVFFENV 1401
Query 1087 NLAKKCLHVVGP-NLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQ 1145
L+ VGP N ++ + +L + +L PL+S GIF + SLQ ++
Sbjct 1402 IEHLSVLNAVGPRNGDSRVEAKLCNVYKAIAKCEGKILTPLISVGIFNVRLETSLQCLLK 1461
Query 1146 TVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPP--NTEDSKTEEKSVVQKPVD 1203
T VND+ L V Y D + +E P TED+ E+ V
Sbjct 1462 T--------VNDRGLN---VFVYTDQERQTIENFFSCSIPVNVTEDNVNHERVSVSFDKT 1510
Query 1204 VKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKL 1239
++K T + + K +TN+L D+ K+
Sbjct 1511 YGEQLKG------TVVIKDKDVTNQLPSAFDVGQKV 1540
Score = 47.4 bits (111), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 71/287 (25%), Positives = 115/287 (40%), Gaps = 31/287 (11%)
Query 1544 TIKVFTTVDNTNLHTQLVDMSMTYGQQF-GPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
+I V T DN N V TYG+Q G + DVT P G+ V+ + D
Sbjct 1488 SIPVNVTEDNVNHERVSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAFDVGQK--VIKAID 1545
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSI--KWADNNCYLSSVLLAL 1660
+ +Y D + SA +H +KF V I K DNNC+++++ LAL
Sbjct 1546 I---DWQAHYGFRDAAAF----SASSH-DAYKFEVVTHSNFIVHKQTDNNCWINAICLAL 1597
Query 1661 QQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLES 1720
Q+L+ ++ P ++ + F ++ S GE GD E M H L
Sbjct 1598 QRLKPQWKFPGVRGLWNEFLERKTQGFVHMLYHISGVKKGEPGDA-ELMLHKLGDLMDND 1656
Query 1721 AKRVL--NVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKT-GVSIPCVCGRDATQYLVQQ 1777
+ ++ C C + VE ++G + L G CV G + Q
Sbjct 1657 CEIIVTHTTACDKCAK-------VEK--FVGPVVAAPLAIHGTDETCVHGVSVNVKVTQI 1707
Query 1778 ESSFVMMS--APPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETL 1822
+ + + S P L+ ++C Y+G+ + GHYT+ + L
Sbjct 1708 KGTVAITSLIGPIIGEVLEATGYIC---YSGSNRNGHYTYYDNRNGL 1751
Score = 45.4 bits (106), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 53/205 (26%), Positives = 85/205 (41%), Gaps = 15/205 (7%)
Query 1633 WKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALIL 1692
+K + G +K DNNC++++ LQ + FN EA+ + + GD +F L
Sbjct 1075 FKTTNLNGKIILKQGDNNCWINACCYQLQAFDF-FN----NEAWEKFKKGDVMDFVNLCY 1129
Query 1693 AYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLS 1752
A + G GD + +L + +AK VL C CG+K L E ++ T
Sbjct 1130 AATTLARGHSGDAEYLLELMLN--DYSTAKIVLAAKCG-CGEKEIVL---ERAVFKLTPL 1183
Query 1753 YDNLKTGVSIPCVCGRDATQYLVQQESSFV--MMSAPPAEYKLQQGTFLCANEYTGNYQC 1810
++ GV C+ V+ FV ++S E + A YTG Q
Sbjct 1184 KESFNYGVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHA-VYTGTTQN 1242
Query 1811 GHYTHITAKETLYRIDGAHLTKMSE 1835
GHY + E Y +DG + + +
Sbjct 1243 GHYM-VDDIEHGYCVDGMGIKPLKK 1266
>sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=1a PE=3
SV=1
Length=3951
Score = 1094 bits (2829), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 746/2235 (33%), Positives = 1119/2235 (50%), Gaps = 211/2235 (9%)
Query 2256 MDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFF 2315
+ +C F C +CL DSL Y +++ YK + G W Y++F F
Sbjct 1799 LRYCADDFICRVCLHDKDSLHLYKHAYSVE---QVYKDAAS--GFIFNWNWLYLVFLILF 1853
Query 2316 Y--LLGLSAIMQVFFGYFASHFISNS--------WLMWFIISIVQMAPVSAMVRMYIFFA 2365
+ G V Y + + NS +L WF V + + F
Sbjct 1854 VKPVAGF-----VIICYCVKYLVLNSTVLQTGVCFLDWF---------VQTVFSHFNFMG 1899
Query 2366 SFYYIWKSY-----VHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRG 2420
+ +Y W Y VH + C TC +C + R+ R E + +V G K+ +VY N G
Sbjct 1900 AGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYTNSGYN 1959
Query 2421 FCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHL 2480
FCK HNW C NCD + +TF+S EVA +LS + KR + PT + ++VD + + ++L
Sbjct 1960 FCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKPTAYAYHVVDEACLVDDFVNL 2019
Query 2481 YFDKAGQ-KTYERHPLSHFVNLDNLR-ANNTKGSLPINVIVFDGKSKCDESAS------K 2532
+ A K + F D L+ A K +L I DG C+ ++ K
Sbjct 2020 KYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSAHALEEAK 2079
Query 2533 SASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVAT 2592
+A++YY+Q +C+PIL+LDQAL + VS + D S+ SV T
Sbjct 2080 NAAIYYAQYLCKPILILDQALYEQLV-VEPVSKSVIDKVCSILSSIISVD---------T 2129
Query 2593 AHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKD--VIECLKLSHHSDLEVTGDSCNNF 2650
A G D +LS TKD ++ H+ D++ TGD N
Sbjct 2130 AALNYKAGTLRDALLSI---------------TKDEEAVDMAIFCHNHDVDYTGDGFTNV 2174
Query 2651 MLTYN-KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSA 2709
+ +Y +TPRD G I+ +A N +V + V +W + + LS+ K + SA
Sbjct 2175 IPSYGIDTGKLTPRDRGFLINADASIANLRVKNAPPV--VWKFSELIKLSDSCLKYLISA 2232
Query 2710 AKKNNIPFRLTCATTRQVVNVITTKISL--KGGKIVS---TCFKLMLKATLLCVLAALVC 2764
K+ + F +T + +QV+ T K+ + K G IVS CFK K L+ + C
Sbjct 2233 TVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKCFKSYFKWLLIFYILFTAC 2292
Query 2765 ---YIVMPVHTLSIHDGY----TNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQ 2817
Y M V +H Y T + G+K I GV R+I+ D CF+NK FDA++
Sbjct 2293 CSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVPEDTCFSNKFVNFDAFW-- 2350
Query 2818 RGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAING-DFLH---------FLPRVFS 2867
G Y N ++CP+V A+I + G + G+PG V ++G F+H ++P F+
Sbjct 2351 -GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMFIHMTQTERKPWYIPTWFN 2408
Query 2868 --AVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD-TNLLEGSISYSE 2924
VG YT +I F TS + +A C ++ A P YC++ N G++ +
Sbjct 2409 REIVG---YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALPFGS 2464
Query 2925 LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLN 2984
+ P Y +G + P L + VV YCR CE + G C+S + +WVL
Sbjct 2465 IIPHRVYFQPNGVRLIVPQQILH-TPYVVKFVSDSYCRGSVCEYTRPGYCVSLNPQWVLF 2523
Query 2985 NEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKF 3044
N+ Y + GVFCG L+ ++ + V ++ + +I ++V +KF
Sbjct 2524 NDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLATMFLILVVVVLIFAMVIKF 2582
Query 3045 RRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQ 3104
+ VF Y V L+++++ ILC+ S L + V Y Y + + + + H
Sbjct 2583 QGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLYCYASLVTSRNTVIIMHCW 2642
Query 3105 WFAMFSPIVPFWITAIYVFCISLKHCH---WFFNNYLRKRVMFNGVTF-STFEEAALCTF 3160
F IVP W+ Y+ I + W + R +++G F ++ AA TF
Sbjct 2643 LVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKLYDGNEFVGNYDLAAKSTF 2702
Query 3161 LLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSN 3220
++ ++KL +E ++ YL+ Y + KY+SG Y +A LA AL+ + N
Sbjct 2703 VIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQYRN 2759
Query 3221 SGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPR 3280
SG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+ LNGLWL DT+YCPR
Sbjct 2760 SGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIYCPR 2819
Query 3281 HVICTAEDMLNPNYEDLLIRKSNHSFLVQAGN-VQLRVIGHSMQNCLLRLKVDTSNPKTP 3339
HV+ + D+L +NH F V + V L V+ ++ +L L+ +N +TP
Sbjct 2820 HVL---GKFSGDQWNDVLNLANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANAETP 2876
Query 3340 KYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSF 3399
KYKF++ G +F++ Y G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F
Sbjct 2877 KYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNF 2936
Query 3400 CYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGD--- 3456
YMHH+ELP +H GTDL G+FYG +VD + AQ D +T N++AWLYAA+I+
Sbjct 2937 FYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESS 2996
Query 3457 ----RWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELL 3512
+W L T +++D+N A + P + + LSA TG+ D+C L+ ++
Sbjct 2997 FSLPKW-LESTTVSVDDYNKWAGDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIM 3050
Query 3513 --QNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHW-----MLLTFL 3565
+ G ILG EDE TP V Q GV Q F V+ W +L FL
Sbjct 3051 VKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSF---VRKATSWFWSRCVLACFL 3107
Query 3566 TSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLAT-- 3623
L +V T L F+VY L +MA+ + VKH A++ FLLP+L T
Sbjct 3108 FVLCAIVLFTAVPLKFYVYAAVIL-----LMAVLFIS-FTVKHVMAYMDTFLLPTLITVI 3161
Query 3624 ------------------VAYFNMVYMPASWVMRIMTWLELADTSLSGYR-LKDCVMYAS 3664
V + + Y P + ++ W+ L + ++ ++ C M +
Sbjct 3162 IGVCAEVPFIYNTLISQVVIFLSQWYDPVVF-DTMVPWMFLPLVLYTAFKCVQGCYMNSF 3220
Query 3665 ALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGV 3724
LL+L + ++T N +T + GN W L +
Sbjct 3221 NTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN--------WELFFELVHTTVLA 3265
Query 3725 VTTIMFLARAIVFVCVE---YYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYF 3781
+ L VF C + YY N + ++V C +G+ C CYFGL+ +N+ F
Sbjct 3266 NVSSNSLIGLFVFKCAKWMLYYCNATYLNNYVLMAVMVNC-IGWLCTCYFGLYWWVNKVF 3324
Query 3782 RLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSD 3841
LTLG Y++ VS ++RYM + PPK+ + F NI + GIGG + +ATVQ+K+SD
Sbjct 3325 GLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLPIATVQAKLSD 3384
Query 3842 VKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGA 3901
VKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E + ++ +L L +
Sbjct 3385 VKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGECMDNLLGMLITLFCIDST 3444
Query 3902 VDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVAN----GDSEVVLKKL 3957
+D++ C+++L LQ++ EFS +PSYA Y A+ YE+ + + G ++ L
Sbjct 3445 IDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAAY 3504
Query 3958 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4017
+K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K+
Sbjct 3505 RKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKI 3564
Query 4018 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQ 4077
D++ LN + + A G VPL +P+ + KL +V+PD T+ +G TY++ +W I
Sbjct 3565 DSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDT 3624
Query 4078 VVDADSKIVQLSEINMD-----NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQM 4129
V+DAD + + + N+AWPL V R V LQNNEL P ++
Sbjct 3625 VIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNKVDVVLQNNELMPHGVKTK 3684
Query 4130 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4189
+C AG Q C+ ++ YY N G V A+ S + +LK A F G IY +L+PP
Sbjct 3685 ACVAGVDQAHCSVESK-CYYTNISGNSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDPP 3742
Query 4190 CRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFCA 4248
C+F +V YLYFIK ++ RGMVLG+++ V LQ+ G+ TE +LS C+
Sbjct 3743 CKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLCS 3802
Query 4249 FAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCR 4308
FAVDPA Y Y+A+G QP+ NCVKML H G+G AIT P DQ+S+GGAS CLYCR
Sbjct 3803 FAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYCR 3862
Query 4309 CHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLR 4364
HI HP N G C KG +VQIPTT DPVGF LRN VCTVC W GYGC CD LR
Sbjct 3863 AHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSLR 3921
Query 4365 EP---LMQSADASTF 4376
+P + A AS F
Sbjct 3922 QPKSSVQSVAGASDF 3936
Score = 65.1 bits (157), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 57/220 (26%), Positives = 95/220 (43%), Gaps = 14/220 (6%)
Query 1570 QFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNH 1629
QFG Y V + E K +P+ D EYY LD Y+ L
Sbjct 1202 QFGQVYAKNKIVFTAD---DVEDKEILYVPTTD---KSILEYY-GLDAQKYVIYLQTL-- 1252
Query 1630 TKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCA 1689
+KW ++W D NC++SS ++ LQ +++F L EA+ + GD +F A
Sbjct 1253 AQKWNVQYRDNFLILEWRDGNCWISSAIVLLQAAKIRFKG-FLTEAWAKLLGGDPTDFVA 1311
Query 1690 LILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLN--VVCKHCGQKTTTLTGVEA-VM 1746
A VG+ D + +L +H + + L V C +CG K+ L G+EA +
Sbjct 1312 WCYASCTAKVGDFSDANWLLANLAEHFDADYTNAFLKKRVSC-NCGIKSYELRGLEACIQ 1370
Query 1747 YMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSA 1786
+ + + KT S CG + T +++ ++++ A
Sbjct 1371 PVRATNLLHFKTQYSNCPTCGANNTDEVIEASLPYLLLFA 1410
Score = 49.7 bits (117), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 15/186 (8%)
Query 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
V I K IVNAAN H+ HG GVA A+ + +DY+K +GP
Sbjct 1025 VVIAKALDEFKEFCIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ---R 1081
Query 1081 CLLSGHNLAKKCL-HVVGPNLNAGEDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPL 1137
+ +C+ +VVGP + L AAY+N ++ + P+LS GIFG
Sbjct 1082 LVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGV--- 1138
Query 1138 QSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSV 1197
++ + +R + + + L + +++D KQ+ TED + +S+
Sbjct 1139 -DFKMSIDAMR-EAFEGCTIRVLLFSLSQEHIDYFDVTC---KQKTIYLTEDG-VKYRSI 1192
Query 1198 VQKPVD 1203
V KP D
Sbjct 1193 VLKPGD 1198
>sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=1a PE=1 SV=1
Length=3951
Score = 1094 bits (2829), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 746/2235 (33%), Positives = 1119/2235 (50%), Gaps = 211/2235 (9%)
Query 2256 MDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFF 2315
+ +C F C +CL DSL Y +++ YK + G W Y++F F
Sbjct 1799 LRYCADDFICRVCLHDKDSLHLYKHAYSVE---QVYKDAAS--GFIFNWNWLYLVFLILF 1853
Query 2316 Y--LLGLSAIMQVFFGYFASHFISNS--------WLMWFIISIVQMAPVSAMVRMYIFFA 2365
+ G V Y + + NS +L WF V + + F
Sbjct 1854 VKPVAGF-----VIICYCVKYLVLNSTVLQTGVCFLDWF---------VQTVFSHFNFMG 1899
Query 2366 SFYYIWKSY-----VHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRG 2420
+ +Y W Y VH + C TC +C + R+ R E + +V G K+ +VY N G
Sbjct 1900 AGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYTNSGYN 1959
Query 2421 FCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHL 2480
FCK HNW C NCD + +TF+S EVA +LS + KR + PT + ++VD + + ++L
Sbjct 1960 FCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKPTAYAYHVVDEACLVDDFVNL 2019
Query 2481 YFDKAGQ-KTYERHPLSHFVNLDNLR-ANNTKGSLPINVIVFDGKSKCDESAS------K 2532
+ A K + F D L+ A K +L I DG C+ ++ K
Sbjct 2020 KYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSAHALEEAK 2079
Query 2533 SASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVAT 2592
+A++YY+Q +C+PIL+LDQAL + VS + D S+ SV T
Sbjct 2080 NAAIYYAQYLCKPILILDQALYEQLV-VEPVSKSVIDKVCSILSSIISVD---------T 2129
Query 2593 AHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKD--VIECLKLSHHSDLEVTGDSCNNF 2650
A G D +LS TKD ++ H+ D++ TGD N
Sbjct 2130 AALNYKAGTLRDALLSI---------------TKDEEAVDMAIFCHNHDVDYTGDGFTNV 2174
Query 2651 MLTYN-KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSA 2709
+ +Y +TPRD G I+ +A N +V + V +W + + LS+ K + SA
Sbjct 2175 IPSYGIDTGKLTPRDRGFLINADASIANLRVKNAPPV--VWKFSELIKLSDSCLKYLISA 2232
Query 2710 AKKNNIPFRLTCATTRQVVNVITTKISL--KGGKIVS---TCFKLMLKATLLCVLAALVC 2764
K+ + F +T + +QV+ T K+ + K G IVS CFK K L+ + C
Sbjct 2233 TVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKCFKSYFKWLLIFYILFTAC 2292
Query 2765 ---YIVMPVHTLSIHDGY----TNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQ 2817
Y M V +H Y T + G+K I GV R+I+ D CF+NK FDA++
Sbjct 2293 CSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVPEDTCFSNKFVNFDAFW-- 2350
Query 2818 RGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAING-DFLH---------FLPRVFS 2867
G Y N ++CP+V A+I + G + G+PG V ++G F+H ++P F+
Sbjct 2351 -GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMFIHMTQTERKPWYIPTWFN 2408
Query 2868 --AVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD-TNLLEGSISYSE 2924
VG YT +I F TS + +A C ++ A P YC++ N G++ +
Sbjct 2409 REIVG---YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALPFGS 2464
Query 2925 LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLN 2984
+ P Y +G + P L + VV YCR CE + G C+S + +WVL
Sbjct 2465 IIPHRVYFQPNGVRLIVPQQILH-TPYVVKFVSDSYCRGSVCEYTRPGYCVSLNPQWVLF 2523
Query 2985 NEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKF 3044
N+ Y + GVFCG L+ ++ + V ++ + +I ++V +KF
Sbjct 2524 NDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLATMFLILVVVVLIFAMVIKF 2582
Query 3045 RRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQ 3104
+ VF Y V L+++++ ILC+ S L + V Y Y + + + + H
Sbjct 2583 QGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLYCYASLVTSRNTVIIMHCW 2642
Query 3105 WFAMFSPIVPFWITAIYVFCISLKHCH---WFFNNYLRKRVMFNGVTF-STFEEAALCTF 3160
F IVP W+ Y+ I + W + R +++G F ++ AA TF
Sbjct 2643 LVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKLYDGNEFVGNYDLAAKSTF 2702
Query 3161 LLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSN 3220
++ ++KL +E ++ YL+ Y + KY+SG Y +A LA AL+ + N
Sbjct 2703 VIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQYRN 2759
Query 3221 SGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPR 3280
SG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+ LNGLWL DT+YCPR
Sbjct 2760 SGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIYCPR 2819
Query 3281 HVICTAEDMLNPNYEDLLIRKSNHSFLVQAGN-VQLRVIGHSMQNCLLRLKVDTSNPKTP 3339
HV+ + D+L +NH F V + V L V+ ++ +L L+ +N +TP
Sbjct 2820 HVL---GKFSGDQWNDVLNLANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANAETP 2876
Query 3340 KYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSF 3399
KYKF++ G +F++ Y G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F
Sbjct 2877 KYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNF 2936
Query 3400 CYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGD--- 3456
YMHH+ELP +H GTDL G+FYG +VD + AQ D +T N++AWLYAA+I+
Sbjct 2937 FYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESS 2996
Query 3457 ----RWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELL 3512
+W L T +++D+N A + P + + LSA TG+ D+C L+ ++
Sbjct 2997 FSLPKW-LESTTVSVDDYNKWAGDNGFTPFSTSTA--ITKLSAITGV---DVCKLLRTIM 3050
Query 3513 --QNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHW-----MLLTFL 3565
+ G ILG EDE TP V Q GV Q F V+ W +L FL
Sbjct 3051 VKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSF---VRKATSWFWSRCVLACFL 3107
Query 3566 TSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLAT-- 3623
L +V T L F+VY L +MA+ + VKH A++ FLLP+L T
Sbjct 3108 FVLCAIVLFTAVPLKFYVYAAVIL-----LMAVLFIS-FTVKHVMAYMDTFLLPTLITVI 3161
Query 3624 ------------------VAYFNMVYMPASWVMRIMTWLELADTSLSGYR-LKDCVMYAS 3664
V + + Y P + ++ W+ L + ++ ++ C M +
Sbjct 3162 IGVCAEVPFIYNTLISQVVIFLSQWYDPVVF-DTMVPWMFLPLVLYTAFKCVQGCYMNSF 3220
Query 3665 ALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGV 3724
LL+L + ++T N +T + GN W L +
Sbjct 3221 NTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN--------WELFFELVHTTVLA 3265
Query 3725 VTTIMFLARAIVFVCVE---YYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYF 3781
+ L VF C + YY N + ++V C +G+ C CYFGL+ +N+ F
Sbjct 3266 NVSSNSLIGLFVFKCAKWMLYYCNATYLNNYVLMAVMVNC-IGWLCTCYFGLYWWVNKVF 3324
Query 3782 RLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSD 3841
LTLG Y++ VS ++RYM + PPK+ + F NI + GIGG + +ATVQ+K+SD
Sbjct 3325 GLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLPIATVQAKLSD 3384
Query 3842 VKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGA 3901
VKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E + ++ +L L +
Sbjct 3385 VKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGECMDNLLGMLITLFCIDST 3444
Query 3902 VDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVAN----GDSEVVLKKL 3957
+D++ C+++L LQ++ EFS +PSYA Y A+ YE+ + + G ++ L
Sbjct 3445 IDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAAY 3504
Query 3958 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4017
+K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K+
Sbjct 3505 RKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKI 3564
Query 4018 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQ 4077
D++ LN + + A G VPL +P+ + KL +V+PD T+ +G TY++ +W I
Sbjct 3565 DSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDT 3624
Query 4078 VVDADSKIVQLSEINMD-----NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQM 4129
V+DAD + + + N+AWPL V R V LQNNEL P ++
Sbjct 3625 VIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNKVDVVLQNNELMPHGVKTK 3684
Query 4130 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4189
+C AG Q C+ ++ YY N G V A+ S + +LK A F G IY +L+PP
Sbjct 3685 ACVAGVDQAHCSVESK-CYYTNISGNSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDPP 3742
Query 4190 CRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFCA 4248
C+F +V YLYFIK ++ RGMVLG+++ V LQ+ G+ TE +LS C+
Sbjct 3743 CKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLCS 3802
Query 4249 FAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCR 4308
FAVDPA Y Y+A+G QP+ NCVKML H G+G AIT P DQ+S+GGAS CLYCR
Sbjct 3803 FAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYCR 3862
Query 4309 CHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLR 4364
HI HP N G C KG +VQIPTT DPVGF LRN VCTVC W GYGC CD LR
Sbjct 3863 AHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSLR 3921
Query 4365 EP---LMQSADASTF 4376
+P + A AS F
Sbjct 3922 QPKSSVQSVAGASDF 3936
Score = 65.1 bits (157), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 57/220 (26%), Positives = 95/220 (43%), Gaps = 14/220 (6%)
Query 1570 QFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNH 1629
QFG Y V + E K +P+ D EYY LD Y+ L
Sbjct 1202 QFGQVYAKNKIVFTAD---DVEDKEILYVPTTD---KSILEYY-GLDAQKYVIYLQTL-- 1252
Query 1630 TKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCA 1689
+KW ++W D NC++SS ++ LQ +++F L EA+ + GD +F A
Sbjct 1253 AQKWNVQYRDNFLILEWRDGNCWISSAIVLLQAAKIRFKG-FLTEAWAKLLGGDPTDFVA 1311
Query 1690 LILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLN--VVCKHCGQKTTTLTGVEA-VM 1746
A VG+ D + +L +H + + L V C +CG K+ L G+EA +
Sbjct 1312 WCYASCTAKVGDFSDANWLLANLAEHFDADYTNAFLKKRVSC-NCGIKSYELRGLEACIQ 1370
Query 1747 YMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSA 1786
+ + + KT S CG + T +++ ++++ A
Sbjct 1371 PVRATNLLHFKTQYSNCPTCGANNTDEVIEASLPYLLLFA 1410
Score = 49.7 bits (117), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 51/186 (27%), Positives = 82/186 (44%), Gaps = 15/186 (8%)
Query 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
V I K IVNAAN H+ HG GVA A+ + +DY+K +GP
Sbjct 1025 VVIAKALDEFKEFCIVNAANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ---R 1081
Query 1081 CLLSGHNLAKKCL-HVVGPNLNAGEDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPL 1137
+ +C+ +VVGP + L AAY+N ++ + P+LS GIFG
Sbjct 1082 LVTPSFVKGIQCVNNVVGPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGV--- 1138
Query 1138 QSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSV 1197
++ + +R + + + L + +++D KQ+ TED + +S+
Sbjct 1139 -DFKMSIDAMR-EAFEGCTIRVLLFSLSQEHIDYFDVTC---KQKTIYLTEDG-VKYRSI 1192
Query 1198 VQKPVD 1203
V KP D
Sbjct 1193 VLKPGD 1198
>sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=1a PE=1 SV=1
Length=3953
Score = 1092 bits (2825), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 743/2228 (33%), Positives = 1121/2228 (50%), Gaps = 220/2228 (10%)
Query 2256 MDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFF 2315
+ +C G F C +CL DSL Y +++ YK + G+ W Y++F F
Sbjct 1801 LRYCAGDFTCRVCLHDRDSLHLYKHAYSVE---QIYKDAAS--GINFNWNWLYLVFLILF 1855
Query 2316 ---------------YLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRM 2360
YL+ S ++Q G+ L WF V +
Sbjct 1856 VKPVAGFVIICYCVKYLVLSSTVLQTGVGF----------LDWF---------VKTVFTH 1896
Query 2361 YIFFASFYYIWKSY-----VHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYA 2415
+ F + +Y W Y VH + C TC +C + R+ R E + +V G K+ +VY
Sbjct 1897 FNFMGAGFYFWLFYKIYVQVHHILYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYT 1956
Query 2416 NGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKN 2475
N G FCK HNW C NCD + +TF+S EVA +LS + KR + PT + ++V V +
Sbjct 1957 NSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKPTAYAYHVVYEACVVD 2016
Query 2476 GALHLYFDKA-GQKTYERHPLSHFVNLDNLR-ANNTKGSLPINVIVFDGKSKCDESAS-- 2531
++L + A K + F D L+ A K +L I DG C+ ++
Sbjct 2017 DFVNLKYKAAIPGKDNASSAVKCFSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSAHA 2076
Query 2532 ----KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLK 2587
K+A+VYY+Q +C+PIL+LDQAL + VS + D S SV
Sbjct 2077 LEEAKNAAVYYAQYLCKPILILDQALYEQL-IVEPVSKSVIDKVCSILSNIISVD----- 2130
Query 2588 ALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKD--VIECLKLSHHSDLEVTGD 2645
TA G D +LS TKD ++ H+ ++E TGD
Sbjct 2131 ----TAALNYKAGTLRDALLSI---------------TKDEEAVDMAIFCHNHEVEYTGD 2171
Query 2646 SCNNFMLTYN-KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRK 2704
N + +Y + +TPRD G I+ +A N +V + V +W D + LS+ K
Sbjct 2172 GFTNVIPSYGMDTDKLTPRDRGFLINADASIANLRVKNAPPV--VWKFSDLIKLSDSCLK 2229
Query 2705 QIRSAAKKNNIPFRLTCATTRQVVNVITTKISL--KGGKIVS-------TCFKLMLKATL 2755
+ SA K+ F +T + +QV++ T K+ + K G +++ +CFK + +
Sbjct 2230 YLISATVKSGGRFFITKSGAKQVISCHTQKLLVEKKAGGVINNTFKWFMSCFKWLFVFYI 2289
Query 2756 LCVLAALVCYIVMPVHTLSIHDGY----TNEIIGYKAIQDGVTRDIISTDDCFANKHAGF 2811
L A + Y M ++ +H Y T + G+K I GV R+I+S D+CF+NK F
Sbjct 2290 L-FTACCLGYYYMEMNKSFVHPMYDVNSTLHVEGFKVIDKGVIREIVSEDNCFSNKFVNF 2348
Query 2812 DAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAING-DFLH---------F 2861
DA++ G SY+N+K+CP+V +I + G + G+PG V ++G F+H +
Sbjct 2349 DAFW---GKSYENNKNCPIVTVVIDGD-GTVAVGVPGFVSWVMDGVMFVHMTQTDRRPWY 2404
Query 2862 LPRVFS--AVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD-TNLLEG 2918
+P F+ VG YT +I F TS + +A C ++ A P YC++ N G
Sbjct 2405 IPTWFNREIVG---YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQLYCFNGDNDAPG 2460
Query 2919 SISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTS 2978
++ + + P Y +G + P L + +V YCR CE ++ G C+S
Sbjct 2461 ALPFGSIIPHRVYFQPNGVRLIVPQQILH-TPYIVKFVSDSYCRGSVCEYTKPGYCVSLD 2519
Query 2979 GRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAA 3038
+WVL N+ Y + GVFCG L+ N+ + V ++ + +I +++
Sbjct 2520 SQWVLFNDEYISKPGVFCGSTVRELMFNMVSTFFTGVNP-NIYIQLATMFLILVVIVLIF 2578
Query 3039 YYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVS 3098
+KF+ VF Y +V L+++++ +LC+ S L + V Y Y + + + +
Sbjct 2579 AMVIKFQGVFKAYATIVFTIMLVWVINAFVLCVHSYNSVLAVILLVLYCYASMVTSRNTA 2638
Query 3099 FLAHLQWFAMFSPIVPFWITAIYVFCISLKH---CHWFFNNYLRKRVMFNGVTF-STFEE 3154
+ H F IVP W+ Y+ I + W + R +++G F ++
Sbjct 2639 IIMHCWLVFTFGLIVPTWLACCYLGFILYMYTPLVFWCYGTTKNTRKLYDGNEFVGNYDL 2698
Query 3155 AALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKA 3214
AA TF++ ++KL +E ++ YL+ Y + KY+SG Y +A LA A
Sbjct 2699 AAKSTFVIRGTEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYA 2755
Query 3215 LNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDD 3274
L+ + NSG +V+Y PP+ SI + LQ+GF+K+ PS VE C+V V+ LNGLWL D
Sbjct 2756 LDQYRNSGVEVVYTPPRYSIGVSRLQAGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGD 2815
Query 3275 TVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGN-VQLRVIGHSMQNCLLRLKVDT 3333
++YCPRHV+ + D+L +NH F V N V L V+ ++ +L L+
Sbjct 2816 SIYCPRHVL---GKFSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAV 2872
Query 3334 SNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNID 3393
+N +TPKYKFV+ G +F++ Y G+ G+Y MR N TI+ SFL G+CGSVGFNI+
Sbjct 2873 ANAETPKYKFVKANCGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIE 2932
Query 3394 YDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVI 3453
V+F YMHH+ELP +H GTDL G+FYG +VD + AQ D +T N++AWLYAA+I
Sbjct 2933 KGVVNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAII 2992
Query 3454 N-------GDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA 3506
+ +W L T ++ D+N A + P + + LSA TG+ D+C
Sbjct 2993 SVKESSFSQPKW-LESTTVSIEDYNRWASDNGFTPFSTSTA--ITKLSAITGV---DVCK 3046
Query 3507 ALKELLQNGMNGRT--ILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHW----- 3559
L+ ++ + ILG EDE TP V Q GV Q F V+ W
Sbjct 3047 LLRTIMVKSAQWGSDPILGQYNFEDELTPESVFNQVGGVRLQSSF---VRKATSWFWSRC 3103
Query 3560 MLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLP 3619
+L FL L +V T L F+V+ L +MA+ + VKH A++ FLLP
Sbjct 3104 VLACFLFVLCAIVLFTAVPLKFYVHAAVIL-----LMAVLFIS-FTVKHVMAYMDTFLLP 3157
Query 3620 SLATVAY---------FN-----MVYMPASW----VMRIMT-WLELADTSLSGYR-LKDC 3659
+L TV +N +V + W V M W+ L + ++ ++ C
Sbjct 3158 TLITVIIGVCAEVPFIYNTLISQVVIFLSQWYDPVVFDTMVPWMLLPLVLYTAFKCVQGC 3217
Query 3660 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3719
M + LL+L + ++T N +T + GN W L +
Sbjct 3218 YMNSFNTSLLMLYQ----FMKLGFVIYTSSNTLTAYTE---GN--------WELFFELVH 3262
Query 3720 NYSGVVTTIMFLARAIVFVCVE----YYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
+ L IVF C + Y + L +M+ +G+ C CYFGL+
Sbjct 3263 TIVLANVSSNSLIGLIVFKCAKWMLYYCNATYFNNYVLMAVMV--NGIGWLCTCYFGLYW 3320
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
+N+ F LTLG Y++ VS ++RYM + PPK+ + F NI + GIGG + +ATV
Sbjct 3321 WVNKVFGLTLGKYNFKVSVDQYRYMCLHKVNPPKTVWEVFTTNILIQGIGGDRVLPIATV 3380
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK+SDVKCT+VVL+ +L +L VE++SK+ A V+LHN IL + D E + ++ +L L
Sbjct 3381 QSKLSDVKCTTVVLMQLLTKLNVEANSKMHAYLVELHNKILASDDVGECMDNLLGMLITL 3440
Query 3896 LSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVAN----GDSE 3951
+ +D+ C+++L LQ++ EFS +PSYA Y A+ YE+ +A+ G ++
Sbjct 3441 FCIDSTIDLGEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKSIYEKVLADSKNGGVTQ 3500
Query 3952 VVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLF 4011
L +K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+RAK+ S++ +LF
Sbjct 3501 QELAAYRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLF 3560
Query 4012 TMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASA 4071
+ML+K+D++ LN + + A G VPL +P+ + KL +V+PD T+ +G TY++
Sbjct 3561 SMLKKIDSEKLNVLFDQANSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTV 3620
Query 4072 LWEIQQVVDADSKIVQLSEINMD-----NSPNLAWPLIVTALRANSA---VKLQNNELSP 4123
+W I V DAD + + + N+AWPL V R V LQNNEL P
Sbjct 3621 VWNIDCVTDADGTELHPTSTGSGLTYCISGDNIAWPLKVNLTRNGHNKVDVALQNNELMP 3680
Query 4124 VALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIY 4183
++ +C AG Q C+ ++ YY + G V A+ S + +LK A F G IY
Sbjct 3681 HGVKTKACVAGVDQAHCSVESK-CYYTSISGSSVVAAITSSNPNLKVASFLNEAGN-QIY 3738
Query 4184 TELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA-GNATEVPANST 4242
+L+PPC+F +V YLYFIK ++ RGMVLG+++ V LQ+ G+ TE
Sbjct 3739 VDLDPPCKFGMKVGDKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQSKGHETEEVDAVG 3798
Query 4243 VLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGAS 4302
+LS C+FAVDPA Y Y+A+G QP+ NCVKML H G+G AIT P DQ+S+GGAS
Sbjct 3799 ILSLCSFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSPTPDQDSYGGAS 3858
Query 4303 CCLYCRCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGC 4358
CLYCR HI HP N G C KG +VQIPTT DPVGF LRN VCTVC W GYGC
Sbjct 3859 VCLYCRAHIAHPGGAGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGC 3917
Query 4359 SCDQLREP 4366
CD LR+P
Sbjct 3918 QCDSLRQP 3925
Score = 69.7 bits (169), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 51/198 (26%), Positives = 90/198 (45%), Gaps = 9/198 (5%)
Query 1591 EGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN 1650
E K +P+ D E Y+ LD Y+ L +KW ++W D N
Sbjct 1222 EDKEILFIPTTDKTILE----YYGLDAQKYVTYLQTL--AQKWDVQYRDNFVILEWRDGN 1275
Query 1651 CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMT 1710
C++SS ++ LQ +++F L EA+ + GD +F A A N VG+ D +
Sbjct 1276 CWISSAIVLLQAAKIRFKG-FLAEAWAKLLGGDPTDFVAWCYASCNAKVGDFSDANWLLA 1334
Query 1711 HLLQHANLESAKRVL-NVVCKHCGQKTTTLTGVEA-VMYMGTLSYDNLKTGVSIPCVCGR 1768
+L +H + + +L V +CG K+ L G+EA + + + + KT S CG
Sbjct 1335 NLAEHFDADYTNALLKKCVSCNCGVKSYELRGLEACIQPVRAPNLLHFKTQYSNCPTCGA 1394
Query 1769 DATQYLVQQESSFVMMSA 1786
+T +++ ++++ A
Sbjct 1395 SSTDEVIEASLPYLLLFA 1412
Score = 57.4 bits (137), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 88/355 (25%), Positives = 140/355 (39%), Gaps = 53/355 (15%)
Query 878 EAVVKTL-QPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDA 936
E VK L Q V D+L + G +D A L S + F + + A
Sbjct 870 EGAVKALPQKVIDVLGDWGEAVD----AQEQLCQQESTRVISEKSVEGFTGSCDAMAEQA 925
Query 937 ECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEE-------EEEDWLDDTTEQS 989
EE+EI E ++D P + ET +E +E+ + E+
Sbjct 926 IVEEQEIVPVVEQ---SQDVVVFTPADLEVVKETAEEVDEFILISAVPKEEVVSQEKEEP 982
Query 990 EIEPEPE------------------PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSAN 1031
++E EP T E+P +F Y ++A V I K
Sbjct 983 QVEQEPTLVVKAQREKKAKKFKVKPATCEKP--KFLEYKTCVGDLA---VVIAKALDEFK 1037
Query 1032 PMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKK 1091
IVNAAN H+ HGGGVA A+ + DY+K +GP + +
Sbjct 1038 EFCIVNAANEHMSHGGGVAKAIADFCGPDFVEYCADYVKKHGPQQ---KLVTPSFVKGIQ 1094
Query 1092 CL-HVVGPNLNAGEDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPLQSLQVCVQTVR 1148
C+ +VVGP + L AAY++ ++ + P+LS+GIFG ++ + +R
Sbjct 1095 CVNNVVGPRHGDSNLREKLVAAYKSVLVGGVVNYVVPVLSSGIFGV----DFKISIDAMR 1150
Query 1149 TQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVD 1203
+ + + L + +++D KQ+ TED + +SVV KP D
Sbjct 1151 -EAFKGCAIRVLLFSLSQEHIDYFDATC---KQKTIYLTEDG-VKYRSVVLKPGD 1200
>sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porcine
transmissible gastroenteritis coronavirus (strain FS772/70)
OX=11150 GN=rep PE=3 SV=1
Length=533
Score = 513 bits (1320), Expect = 1e-160, Method: Compositional matrix adjust.
Identities = 261/532 (49%), Positives = 361/532 (68%), Gaps = 8/532 (2%)
Query 6546 SSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNG--VTLIGESVKT 6603
S + FD + G + F R+ VLI+ +VKGL+ K +N V+ +G T
Sbjct 3 SEVVTCFDNSIAGSFERFTTTRDAVLISNNAVKGLSAIK-LQYGLLNDLPVSTVGNKPVT 61
Query 6604 QFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEH 6663
+ Y +K ++Q+ ++Y+TQ R E FKPRS ME DFL + FIQ+Y LE Y FEH
Sbjct 62 WYIYVRKNGEYVEQI-DSYYTQGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEH 120
Query 6664 IVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIP-MDSTVKNYFITDAQTGSSKCVCS 6722
+V+GD S +GG+HL+I + ++ +++F+ DST+K+ IT A SSK VC+
Sbjct 121 VVFGDVSKTTIGGMHLLISQVRLAKMGLFSVQEFMNNSDSTLKSCCITYADDPSSKNVCT 180
Query 6723 VIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQP 6782
+D+LLDDFV IIKS DL+V+SKVV V +D +MLWC++ H++TFYP+LQ+++ W P
Sbjct 181 YMDILLDDFVTIIKSLDLNVVSKVVDVIVDCKAWKWMLWCENSHIKTFYPQLQSAE-WNP 239
Query 6783 GVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRV 6842
G +MP LYK+QRM LE+C+L NYG +P GI NV KYTQLCQYLNT TL VP+ MRV
Sbjct 240 GYSMPTLYKIQRMCLERCNLYNYGAQVKLPDGITTNVVKYTQLCQYLNTTTLCVPHKMRV 299
Query 6843 IHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLI 6902
+H GA GVAPG+ VLR+WLP +LVD+DL D+VSDAD ++ GDC +++ +K+DL+
Sbjct 300 LHLGAAGASGVAPGSTVLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTSLYIEDKFDLL 359
Query 6903 ISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHF 6962
+SD+YD TK + EN SK+GFFTY+ GFIK+KL+LGGS+A+KITE SWN DLY+L+ F
Sbjct 360 VSDLYDGSTKSIDGENTSKDGFFTYINGFIKEKLSLGGSVAIKITEFSWNKDLYELIQRF 419
Query 6963 SWWTAFVTNVNASSSEAFLIGANYLGK--PKEQIDGYTMHANYIFWRNTNPIQLSSYSLF 7020
+WT F T+VN SSSE FLIG NYLG K +DG MHANYIFWRN+ + LS S+
Sbjct 420 EYWTVFCTSVNTSSSEGFLIGINYLGPYCDKAIVDGNIMHANYIFWRNSTIMALSHNSVL 479
Query 7021 DMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
D KF + +++LKE ++N+M+ LL KG+L+IR N +++ + VN
Sbjct 480 DTPKFKCRCNNALIVNLKEKELNEMVIGLLRKGKLLIRNNGKLLNFGNHFVN 531
>sp|Q9WQ77|R1AB_CVRSD Replicase polyprotein 1ab (Fragment) OS=Rat
coronavirus (strain 681) OX=33740 GN=rep PE=3 SV=1
Length=307
Score = 484 bits (1246), Expect = 4e-154, Method: Compositional matrix adjust.
Identities = 224/307 (73%), Positives = 266/307 (87%), Gaps = 0/307 (0%)
Query 4875 FNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICST 4934
FNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI ST
Sbjct 1 FNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILST 60
Query 4935 MTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRA 4994
MT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCDRA
Sbjct 61 MTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCDRA 120
Query 4995 MPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDA 5054
MPN+LRI++SLVLARKH++CC+ + RFYRLANECAQVLSE+VMCGG YVKPGGTSSGDA
Sbjct 121 MPNILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGDA 180
Query 5055 TTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEF 5114
TTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FV E+
Sbjct 181 TTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVSEY 240
Query 5115 YAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDL 5174
Y +L KHFSMMILSDD VVCYNS +A++G +A+I F+ VLYYQNNVFMSEAKCW ETD+
Sbjct 241 YEFLNKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQVLYYQNNVFMSEAKCWVETDI 300
Query 5175 TKGPHEF 5181
KGPHEF
Sbjct 301 EKGPHEF 307
>sp|Q9WQ76|R1AB_CVTMI Replicase polyprotein 1ab (Fragment) OS=Turkey
coronavirus (strain Minnesota) OX=231430 GN=rep PE=3
SV=1
Length=306
Score = 442 bits (1136), Expect = 2e-139, Method: Compositional matrix adjust.
Identities = 212/307 (69%), Positives = 245/307 (80%), Gaps = 1/307 (0%)
Query 4875 FNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICST 4934
FNK+GKARLYY+ MS E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI ST
Sbjct 1 FNKFGKARLYYE-MSLEEQDQLFESTKKNVLPTITQMNLKYAISAKNRARTVAGVSILST 59
Query 4935 MTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRA 4994
MTNRQFHQK+LKSI TR A VVIGT+KFYGGW NML+ + VE P LMGWDYPKCDRA
Sbjct 60 MTNRQFHQKILKSIVNTRNAPVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKCDRA 119
Query 4995 MPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDA 5054
MPN+LRI ASLVLARKH CC S R YRL NECAQVLSE V+ G +YVKPGGTSSGDA
Sbjct 120 MPNLLRITASLVLARKHTNCCTWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSSGDA 179
Query 5055 TTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEF 5114
TTAYANSVFNI QA +ANV LLS I +++LQ+ LY+ +YR + D FV++F
Sbjct 180 TTAYANSVFNIIQATSANVARLLSVITRDIVYDDIKSLQYELYQQVYRRVNFDPAFVEKF 239
Query 5115 YAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDL 5174
Y+YL K+FS+MI +DD VVCYN+ A QGLVA I F+ +LYYQNNV+M+++KCW E DL
Sbjct 240 YSYLCKNFSLMIFADDGVVCYNNTLAKQGLVADISGFREILYYQNNVYMADSKCWVEPDL 299
Query 5175 TKGPHEF 5181
KGPHEF
Sbjct 300 EKGPHEF 306
>sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian
infectious bronchitis virus (strain KB8523) OX=11126 GN=rep
PE=3 SV=1
Length=521
Score = 442 bits (1137), Expect = 3e-136, Method: Compositional matrix adjust.
Identities = 246/520 (47%), Positives = 344/520 (66%), Gaps = 19/520 (4%)
Query 6563 FRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYF--KKVDGIIQQLPE 6620
F A N VL++ K + + P+ V G S+K N + K+V+G LP
Sbjct 7 FLAADNAVLVSTQCYKRHSYVEIPSNLLVQN----GMSLKDGANLYVYKRVNGAFVTLPN 62
Query 6621 TYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLM 6680
T TQ R E F+PRS +E DFL+++ ++F+++Y + +HI+YG+ QLGGLH +
Sbjct 63 TLNTQGRSYETFEPRSDVERDFLDMSEEDFVEKYG-KDLGLQHILYGEVDKPQLGGLHTV 121
Query 6681 IGLAKRSQDSPLKLEDFIPMDSTV-KNYFITDAQTGSSKCVCSVIDLLLDDFVEI---IK 6736
IG+ + + + L + DS V +NYF+ A GS K VC+V+DLLLDDF+E+ I
Sbjct 122 IGMYRLLRANKLNAKSVTNSDSDVMQNYFVL-ADNGSYKQVCTVVDLLLDDFLELLRNIL 180
Query 6737 SQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRML 6796
++ + SKVV V+IDY I+FM W +DG ++T YP+LQ+ AW G MP LYK+Q +
Sbjct 181 NEYGTNKSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQS--AWTCGYNMPELYKVQNCV 238
Query 6797 LEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPG 6856
+E C++ NYG +P GIMMNVAKYTQLCQYL+ T+ VP+NMRV+HFGAGSDKGVAPG
Sbjct 239 MEPCNIPNYGVGITLPSGIMMNVAKYTQLCQYLSKTTVCVPHNMRVMHFGAGSDKGVAPG 298
Query 6857 TAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY---DPRTKH 6913
+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC T +K+DL+ISDMY D + KH
Sbjct 299 STVLKQWLPEGTLLVDTDIVDYVSDAHVSVLSDCNKYKTEHKFDLVISDMYTDNDSKRKH 358
Query 6914 -VTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNV 6972
N+ + F YL F++ LALGGS AVK+TE SW+ LY + +WWT F T V
Sbjct 359 GGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKLTETSWHESLYDIAQDCAWWTMFCTAV 418
Query 6973 NASSSEAFLIGANYLGKP-KEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRG 7031
NASSSEAFLIG NYLG K ++ G T+HANYIFWRN N +Q S+YS+FD++KF L+L+
Sbjct 419 NASSSEAFLIGVNYLGASVKVKVSGKTLHANYIFWRNCNYLQTSAYSIFDVAKFDLRLKA 478
Query 7032 TAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILV 7071
T V++LK Q D++++L++ G+L++R+ +SD V
Sbjct 479 TPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 518
>sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus
HKU4 OX=694007 GN=1a PE=1 SV=1
Length=4434
Score = 310 bits (795), Expect = 2e-82, Method: Compositional matrix adjust.
Identities = 234/757 (31%), Positives = 363/757 (48%), Gaps = 55/757 (7%)
Query 1381 KYKGIKIQEGI--VDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEA 1438
+ KG+ + I VD GV ++ Y++++ + +I N + + MP GYVTHG +L ++
Sbjct 1357 RTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGCSG-ICAMPFGYVTHGLDLAQS 1414
Query 1439 ARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSY-SGQRT 1497
+R +K P V ++S + + N + + +T E F+ V+ G Y W SG
Sbjct 1415 GNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGGYHSWHLVSGDLI 1472
Query 1498 ELGVEFLK----RGDKIVY-----HTLESPVEFHLDGEVLSLDKLKSLLSLREVK--TIK 1546
V + K G I Y + +++ V L+ ++ L+ R + I+
Sbjct 1473 VKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFS----DLEACRAYLTSRAAQQVNIE 1528
Query 1547 VFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRS 1606
V T+D N T +++ + T+ +Q G T+ G D++ P V G++ FV +D+ S
Sbjct 1529 VLVTIDGVNFRTVILNDTTTFRKQLGATFYKGVDISDAFPTVKMGGESLFV--ADNLSES 1586
Query 1607 EAF---EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQL 1663
E EYY T D +FL RY S ++WKF G+ S+K ++ NCY+++ ++ + L
Sbjct 1587 EKVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATIMMIDML 1646
Query 1664 -EVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE-SA 1721
++KF PALQ AY R + GD +F ALI+AY + T D + + LL A L SA
Sbjct 1647 HDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKAELTVSA 1706
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
K V C CG + TG+ A +Y G S + L++ + CVCG + LV+ + +
Sbjct 1707 KMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLVEHSAPW 1766
Query 1782 VMMSAPPAEYKLQQGT---FLCANEYTG-NYQCGHYTHITAKETL-YRIDGAHLTKMSEY 1836
+++S E K+ T + N + G GHY HI K+ L Y+ D LTK S+
Sbjct 1767 LLVSGL-NEVKVSTSTDPIYRAFNVFQGVETSVGHYVHIRVKDGLFYKYDSGSLTKTSDM 1825
Query 1837 KGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQP-IDLVPTQ 1895
K +T V+Y YT V Y LDGVT E+ P L YY KD YYT +P I P
Sbjct 1826 KCKMTSVWYPTVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKPTIKYSPAT 1885
Query 1896 PLPNASFDNFKLTCSNTKFADD-----LNQMTGF--TKPASRELSVTFFPDLNGDVVAID 1948
LP + + N L + D N + GF TKP S++L+ + P+ +GDV+ +
Sbjct 1886 ILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNEDGDVLLSE 1945
Query 1949 YRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVE 2008
+ +Y+ +KKG L KPI+W N KPN LR L+ P+ N + VL
Sbjct 1946 FSNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDNKYTVLQDN 2005
Query 2009 DTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTE---VVGNVILKPSDEGVKVTQ 2065
+Q E P ++V P +++IE K V GN GV V
Sbjct 2006 TSQ-----LVEHNVPVVDDV---PITTRKLIEVKCKGLNKPFVKGNFSFVNDPNGVTVVD 2057
Query 2066 ELGHEDLMAAYVE-NTSITIKKPNELSLALGLKTIAT 2101
LG +L A YV+ NT + + N S L T+ +
Sbjct 2058 TLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVES 2094
Score = 177 bits (448), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 274/1120 (24%), Positives = 455/1120 (41%), Gaps = 145/1120 (13%)
Query 9 NEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEALSEAREHLK-NGTCGLVELE-KGVL 61
NEK HV ++P+ D+ L F D E A ++ LK G V + + +
Sbjct 22 NEKRSDHVACTVPLCDTDDMACKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRAM 80
Query 62 PQLEQPYVFIKRSDALSTNHGHKVVELVAEMD--GIQYGRSGIT---LGVLVPHVGETPI 116
L P V++ H +V +A D G R+ + LG+ P+
Sbjct 81 KFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDQVGAAMMRTTLNAKPLGMFFPYDSSLET 140
Query 117 AYRNVLLRKNGNKGAGGHSYGIDLKS---YDLGDELGTDPIEDYEQNWNTKHGSGALREL 173
LLRKNG G D K ++ D+L DP Y QN L
Sbjct 141 GEYTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------L 188
Query 174 TRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSE-QLDY---IESKRGVY 229
++L GG +D CG +G P+ +A+ G + TL++ ++D ++S R +
Sbjct 189 LKKLIGGDCIP-IDQYMCGKNGKPIADYAKIVAKEG--LTTLADIEVDVKSRMDSDRFI- 244
Query 230 CCRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQP-RV 288
+ + W R + Y QT F I S + D K P+ F + S++ ++ P +
Sbjct 245 VLNKKLYRVVWNVTRRNVPYPKQTAFTIVSVVQCDD-KDSVPEHTFTIGSQILMVSPLKA 303
Query 289 EKKKTEGFMGRI-RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTE 347
K R+ + Y + Q+ ++ S + CN C +W T + ++ CG
Sbjct 304 TNNKNFNLKQRLLYTFYGKDAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGAN 363
Query 348 NLVIE-GPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGR--TR 404
+ + G +P NA+ CP + HS A +N + + + GG+ T
Sbjct 364 YSANDVDLQSSGLVPRNALFLANCPCANNGAC--SHSAAQVYNILDGKACVEVGGKSFTL 421
Query 405 CFGGCVFAYVGCYNKRAYWVPRASA-------DIGSGHTGITGDNVETLNEDLLEILSRE 457
FGG V+AY+GC + Y+VPRA + I +G TG VET N L +
Sbjct 422 TFGGVVYAYMGCCDGTMYFVPRAKSCVSRIGDAIFTGCTGTWDKVVETAN----LFLEKA 477
Query 458 RVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGN--YKVTKGK 515
+ ++N F L E ++LA S +TS F + S++ + + N + VT G
Sbjct 478 QRSLNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGD 534
Query 516 PVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISE 575
++ A NIG V P A + F + +L+ A LD S
Sbjct 535 YIRDAINIGAN-GVCNATINAPFIAFTGLGESFKKVSAIPWKICSNLKSA----LDYYSS 589
Query 576 QSLRLV-------DAMVYTSDLLTNSVIIMA---YVTGGLVQQTSQWLSNLLGTTVEKLR 625
+ V D + LL + +A +V L ++ L + L
Sbjct 590 NIMFRVFPYDIPCDVSNFVELLLDCGKLTVATSYFVLRYLDEKFDTVLGTVSSACQTALS 649
Query 626 PIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVK-GQIQVASDNIKDCVKCFIDVVNK 684
A A F+ D +++ K L+ ++ G + VA + K V+ +D+++K
Sbjct 650 SFLNACVAASRATAGFINDMFKLFKVLMHKLYVYTSCGYVAVAEHSSK-IVQQVLDIMSK 708
Query 685 ALEMCIDQVTIAGAKLRSL----------NLGEVFIAQSKGLYRQCIRGKEQLQLLMPLK 734
A+++ V+ AG KL ++ N G F +K + ++G Q+ L++P
Sbjct 709 AMKLLHTNVSWAGTKLSAIIYEGREALLFNSGTYFCLSTKA---KTLQG--QMNLVLPGD 763
Query 735 APKEVTFL-----EGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLM 789
K+ + D+ D S V + +G+LE P + IVG V V+ +
Sbjct 764 YNKKTLGILDPVPNADTIDVNANSTVVDVVHGQLE----PTNEHGPSMIVGNYVLVSDKL 819
Query 790 LLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDER 849
+ +D+E Y + G + + +FRLKGG P K VTFG+ EV Y++V IT+++
Sbjct 820 FVRTEDEEFYPLCTNGKVVS-TLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPV 878
Query 850 VDKVL-NEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYL 908
+D +L + K + +TVE V +F V+ + V+ L P+ G D++++ Y+
Sbjct 879 LDALLSSSKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYV 938
Query 909 FDDAGEENFSSRMYCSFYP-----------------------PDEEEEDDAECEEEEIDE 945
++ G+ +SS M S P DEE A E +D+
Sbjct 939 YNQDGDCAWSSNMTFSINPVEDVEEVEEFIEDDYLSDELPIADDEEAWARAVEEVMPLDD 998
Query 946 TCEHEYGTEDDYQGLPLEFG---ASAETVRVEEEEEE--DWLDDTTEQSEIEPEPEPT-- 998
E E+D PLE AE V E +E + +D T S + E + +
Sbjct 999 ILVAEIELEED---PPLETALESVEAEVVETAEAQEPSVESIDSTPSTSTVVGENDLSVK 1055
Query 999 PEEPVNQFTGYLKL---------TDNVAIKCVDIVKEAQS 1029
P V + L+L +D AI DIV Q+
Sbjct 1056 PMSRVAETDDVLELETAVVGGPVSDVTAIVTNDIVSVEQA 1095
Score = 133 bits (334), Expect = 9e-29, Method: Compositional matrix adjust.
Identities = 75/188 (40%), Positives = 105/188 (56%), Gaps = 6/188 (3%)
Query 960 LPLEFGASAETV-RVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLK-----LT 1013
LP++ AS V +V + + + L T+ ++P + P K +
Sbjct 1103 LPIQDEASENQVHQVSDLQGNELLCSETKVEIVQPRQDLKPRRSRKSKVDLSKYKHTVIN 1162
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNG 1073
++V + D ++ A ++VNAAN HLKHGGG+AG +NKA+ G +Q+ESD+YI NG
Sbjct 1163 NSVTLVLGDAIQIASLLPKCILVNAANRHLKHGGGIAGVINKASGGDVQEESDEYISNNG 1222
Query 1074 PLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFG 1133
PL VG S LL GH LA LHVVGP+ ED LLK Y+ FN I++ PL+SAGIF
Sbjct 1223 PLHVGDSVLLKGHGLADAILHVVGPDARNNEDAALLKRCYKAFNKHTIVVTPLISAGIFS 1282
Query 1134 AKPLQSLQ 1141
P S +
Sbjct 1283 VDPKVSFE 1290
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 310 bits (794), Expect = 3e-82, Method: Compositional matrix adjust.
Identities = 234/757 (31%), Positives = 363/757 (48%), Gaps = 55/757 (7%)
Query 1381 KYKGIKIQEGI--VDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEA 1438
+ KG+ + I VD GV ++ Y++++ + +I N + + MP GYVTHG +L ++
Sbjct 1357 RTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGCSG-ICAMPFGYVTHGLDLAQS 1414
Query 1439 ARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSY-SGQRT 1497
+R +K P V ++S + + N + + +T E F+ V+ G Y W SG
Sbjct 1415 GNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGGYHSWHLVSGDLI 1472
Query 1498 ELGVEFLK----RGDKIVY-----HTLESPVEFHLDGEVLSLDKLKSLLSLREVK--TIK 1546
V + K G I Y + +++ V L+ ++ L+ R + I+
Sbjct 1473 VKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFS----DLEACRAYLTSRAAQQVNIE 1528
Query 1547 VFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRS 1606
V T+D N T +++ + T+ +Q G T+ G D++ P V G++ FV +D+ S
Sbjct 1529 VLVTIDGVNFRTVILNDTTTFRKQLGATFYKGVDISDAFPTVKMGGESLFV--ADNLSES 1586
Query 1607 EAF---EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQL 1663
E EYY T D +FL RY S ++WKF G+ S+K ++ NCY+++ ++ + L
Sbjct 1587 EKVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATIMMIDML 1646
Query 1664 -EVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE-SA 1721
++KF PALQ AY R + GD +F ALI+AY + T D + + LL A L SA
Sbjct 1647 HDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKAELTVSA 1706
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
K V C CG + TG+ A +Y G S + L++ + CVCG + LV+ + +
Sbjct 1707 KMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLVEHSAPW 1766
Query 1782 VMMSAPPAEYKLQQGT---FLCANEYTG-NYQCGHYTHITAKETL-YRIDGAHLTKMSEY 1836
+++S E K+ T + N + G GHY HI K+ L Y+ D LTK S+
Sbjct 1767 LLVSGL-NEVKVSTSTDPIYRAFNVFQGVETSVGHYVHIRVKDGLFYKYDSGSLTKTSDM 1825
Query 1837 KGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQP-IDLVPTQ 1895
K +T V+Y YT V Y LDGVT E+ P L YY KD YYT +P I P
Sbjct 1826 KCKMTSVWYPTVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKPTIKYSPAT 1885
Query 1896 PLPNASFDNFKLTCSNTKFADD-----LNQMTGF--TKPASRELSVTFFPDLNGDVVAID 1948
LP + + N L + D N + GF TKP S++L+ + P+ +GDV+ +
Sbjct 1886 ILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNEDGDVLLSE 1945
Query 1949 YRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVE 2008
+ +Y+ +KKG L KPI+W N KPN LR L+ P+ N + VL
Sbjct 1946 FSNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDNKYTVLQDN 2005
Query 2009 DTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTE---VVGNVILKPSDEGVKVTQ 2065
+Q E P ++V P +++IE K V GN GV V
Sbjct 2006 TSQ-----LVEHNVPVVDDV---PITTRKLIEVKCKGLNKPFVKGNFSFVNDPNGVTVVD 2057
Query 2066 ELGHEDLMAAYVE-NTSITIKKPNELSLALGLKTIAT 2101
LG +L A YV+ NT + + N S L T+ +
Sbjct 2058 TLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVES 2094
Score = 177 bits (450), Expect = 3e-42, Method: Compositional matrix adjust.
Identities = 273/1120 (24%), Positives = 453/1120 (40%), Gaps = 145/1120 (13%)
Query 9 NEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEALSEAREHLK-NGTCGLVELE-KGVL 61
NEK HV ++P+ D+ L F D E A ++ LK G V + + +
Sbjct 22 NEKRSDHVACTVPLCDTDDMACKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRAM 80
Query 62 PQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITL-----GVLVPHVGETPI 116
L P V++ H +V +A D + TL G+ P+
Sbjct 81 KFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDQVGAAMMRTTLNAKPLGMFFPYDSSLET 140
Query 117 AYRNVLLRKNGNKGAGGHSYGIDLKS---YDLGDELGTDPIEDYEQNWNTKHGSGALREL 173
LLRKNG G D K ++ D+L DP Y QN L
Sbjct 141 GEYTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------L 188
Query 174 TRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSE-QLDY---IESKRGVY 229
++L GG +D CG +G P+ +A+ G + TL++ ++D ++S R +
Sbjct 189 LKKLIGGDCIP-IDQYMCGKNGKPIADYAKIVAKEG--LTTLADIEVDVKSRMDSDRFI- 244
Query 230 CCRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQP-RV 288
+ + W R + Y QT F I S + D K P+ F + S++ ++ P +
Sbjct 245 VLNKKLYRVVWNVTRRNVPYPKQTAFTIVSVVQCDD-KDSVPEHTFTIGSQILMVSPLKA 303
Query 289 EKKKTEGFMGRI-RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTE 347
K R+ + Y + Q+ ++ S + CN C +W T + ++ CG
Sbjct 304 TNNKNFNLKQRLLYTFYGKDAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGAN 363
Query 348 NLVIE-GPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGR--TR 404
+ + G +P NA+ CP + HS A +N + + + GG+ T
Sbjct 364 YSANDVDLQSSGLVPRNALFLANCPCANNGAC--SHSAAQVYNILDGKACVEVGGKSFTL 421
Query 405 CFGGCVFAYVGCYNKRAYWVPRASA-------DIGSGHTGITGDNVETLNEDLLEILSRE 457
FGG V+AY+GC + Y+VPRA + I +G TG VET N L +
Sbjct 422 TFGGVVYAYMGCCDGTMYFVPRAKSCVSRIGDAIFTGCTGTWDKVVETAN----LFLEKA 477
Query 458 RVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGN--YKVTKGK 515
+ ++N F L E ++LA S +TS F + S++ + + N + VT G
Sbjct 478 QRSLNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGD 534
Query 516 PVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISE 575
++ A NIG V P A + F + +L+ A LD S
Sbjct 535 YIRDAINIGAN-GVCNATINAPFIAFTGLGESFKKVSAIPWKICSNLKSA----LDYYSS 589
Query 576 QSLRLV-------DAMVYTSDLLTNSVIIMA---YVTGGLVQQTSQWLSNLLGTTVEKLR 625
+ V D + LL + +A +V L ++ L + L
Sbjct 590 NIMFRVFPYDIPCDVSNFVELLLDCGKLTVATSYFVLRYLDEKFDTVLGTVSSACQTALS 649
Query 626 PIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVK-GQIQVASDNIKDCVKCFIDVVNK 684
A A F+ D +++ K L+ ++ G + VA + K V+ +D+++K
Sbjct 650 SFLNACVAASRATAGFINDMFKLFKVLMHKLYVYTSCGYVAVAEHSSK-IVQQVLDIMSK 708
Query 685 ALEMCIDQVTIAGAKLRSL----------NLGEVFIAQSKGLYRQCIRGKEQLQLLMPLK 734
A+++ V+ AG KL ++ N G F +K + ++G Q+ L++P
Sbjct 709 AMKLLHTNVSWAGTKLSAIIYEGREALLFNSGTYFCLSTKA---KTLQG--QMNLVLPGD 763
Query 735 APKEVTFL-----EGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLM 789
K+ + D+ D S V + +G+LE P + IVG V V+ +
Sbjct 764 YNKKTLGILDPVPNADTIDVNANSTVVDVVHGQLE----PTNEHGPSMIVGNYVLVSDKL 819
Query 790 LLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDER 849
+ +D+E Y + G + + +FRLKGG P K VTFG+ EV Y++V IT+++
Sbjct 820 FVRTEDEEFYPLCTNGKVVS-TLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPV 878
Query 850 VDKVL-NEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYL 908
+D +L + K + +TVE V +F V+ + V+ L P+ G D++++ Y+
Sbjct 879 LDALLSSSKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYV 938
Query 909 FDDAGEENFSSRMYCSFYP-----------------------PDEEEEDDAECEEEEIDE 945
++ G+ +SS M S P DEE A E +D+
Sbjct 939 YNQDGDCAWSSNMTFSINPVEDVEEVEEFIEDDYLSDELPIADDEEAWARAVEEVMPLDD 998
Query 946 TCEHEYGTEDDYQGLPLEFG---ASAETVRVEEEEEE--DWLDDTTEQSEIEPEPEPT-- 998
E E+D PLE AE V E +E + +D T S + E + +
Sbjct 999 ILVAEIELEED---PPLETALESVEAEVVETAEAQEPSVESIDSTPSTSTVVGENDLSVK 1055
Query 999 PEEPVNQFTGYLKL---------TDNVAIKCVDIVKEAQS 1029
P V + L+L +D AI DIV Q+
Sbjct 1056 PMSRVAETDDVLELETAVVGGPVSDVTAIVTNDIVSVEQA 1095
Score = 133 bits (335), Expect = 8e-29, Method: Compositional matrix adjust.
Identities = 75/188 (40%), Positives = 105/188 (56%), Gaps = 6/188 (3%)
Query 960 LPLEFGASAETV-RVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLK-----LT 1013
LP++ AS V +V + + + L T+ ++P + P K +
Sbjct 1103 LPIQDEASENQVHQVSDLQGNELLCSETKVEIVQPRQDLKPRRSRKSKVDLSKYKHTVIN 1162
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNG 1073
++V + D ++ A ++VNAAN HLKHGGG+AG +NKA+ G +Q+ESD+YI NG
Sbjct 1163 NSVTLVLGDAIQIASLLPKCILVNAANRHLKHGGGIAGVINKASGGDVQEESDEYISNNG 1222
Query 1074 PLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFG 1133
PL VG S LL GH LA LHVVGP+ ED LLK Y+ FN I++ PL+SAGIF
Sbjct 1223 PLHVGDSVLLKGHGLADAILHVVGPDARNNEDAALLKRCYKAFNKHTIVVTPLISAGIFS 1282
Query 1134 AKPLQSLQ 1141
P S +
Sbjct 1283 VDPKVSFE 1290
>sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus
133/2005 OX=389230 GN=1a PE=3 SV=1
Length=4441
Score = 308 bits (789), Expect = 1e-81, Method: Compositional matrix adjust.
Identities = 233/757 (31%), Positives = 363/757 (48%), Gaps = 55/757 (7%)
Query 1381 KYKGIKIQEGI--VDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEA 1438
+ KG+ + I VD GV ++ Y++++ + +I N + MP GYVTHG +L ++
Sbjct 1364 RTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGC-PGICAMPFGYVTHGLDLAQS 1421
Query 1439 ARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSY-SGQRT 1497
+R +K P V ++S + + N + + +T E F+ V+ G Y W SG
Sbjct 1422 GNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGGYHSWHLVSGDLI 1479
Query 1498 ELGVEFLK----RGDKIVY-----HTLESPVEFHLDGEVLSLDKLKSLLSLREVK--TIK 1546
V + K G I Y + +++ V L+ ++ L+ R + I+
Sbjct 1480 VKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFS----DLEACRAYLTSRAAQQVNIE 1535
Query 1547 VFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRS 1606
V T+D N T +++ + T+ +Q G T+ G D++ P V G++ FV +D+ S
Sbjct 1536 VLVTIDGVNFRTVILNDATTFRKQLGATFYKGVDISDALPTVKMGGESLFV--ADNLSES 1593
Query 1607 EAF---EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQL 1663
E EYY T D +FL RY S ++WKF G+ S+K ++ NCY+++ ++ + L
Sbjct 1594 EEVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATIMMIDML 1653
Query 1664 -EVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE-SA 1721
++KF PALQ AY R + GD +F ALI+AY + T D + + LL A L SA
Sbjct 1654 HDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKAELTVSA 1713
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
K V C CG + TG+ A +Y G S + L++ + CVCG + LV+ + +
Sbjct 1714 KMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLVEHSTPW 1773
Query 1782 VMMSAPPAEYKLQQGT---FLCANEYTG-NYQCGHYTHITAKETL-YRIDGAHLTKMSEY 1836
+++S E K+ T + N + G GHY H+ K+ L Y+ D LTK S+
Sbjct 1774 LLVSGL-NEVKVSTSTDPVYRAFNVFQGVETSVGHYVHVRVKDGLFYKYDSGSLTKTSDM 1832
Query 1837 KGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQP-IDLVPTQ 1895
K +T V+Y + YT V Y LDGVT E+ P L YY KD YYT +P I P
Sbjct 1833 KCKMTSVWYPKVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKPTIKYSPAT 1892
Query 1896 PLPNASFDNFKLTCSNTKFADD-----LNQMTGF--TKPASRELSVTFFPDLNGDVVAID 1948
LP + + N L + D N + GF TKP S++L+ + P+ +GDV+ +
Sbjct 1893 ILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNEDGDVLLSE 1952
Query 1949 YRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVE 2008
+ +Y+ +KKG L KPI+W N KPN LR L+ P+ N + VL
Sbjct 1953 FNNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDNKYTVLQDN 2012
Query 2009 DTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTE---VVGNVILKPSDEGVKVTQ 2065
+Q + E P E+V +++IE K V GN GV V
Sbjct 2013 TSQLI-----EPNVPVVEDV---SITTRKLIEVKCKGLNKPFVKGNFSFVNDPNGVTVVD 2064
Query 2066 ELGHEDLMAAYVE-NTSITIKKPNELSLALGLKTIAT 2101
LG +L A YV+ NT + + N S L T+ +
Sbjct 2065 TLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVES 2101
Score = 176 bits (445), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 261/1084 (24%), Positives = 440/1084 (41%), Gaps = 152/1084 (14%)
Query 9 NEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEALSEAREHLK-NGTCGLVELE-KGVL 61
NEK HV ++P+ D+ L F D E A ++ LK G V + + +
Sbjct 22 NEKRSDHVACTVPLCDTEDMASKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRAM 80
Query 62 PQLEQPYVFIKRSDALSTNHGHKVVELVAEMD--GIQYGRSGIT---LGVLVPHVGETPI 116
L P V++ H +V +A D G R+ + LG+ P+
Sbjct 81 KFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDHVGAAMMRTTLNVKPLGMFFPYDSSLET 140
Query 117 AYRNVLLRKNGNKGAGGHSYGIDLKS---YDLGDELGTDPIEDYEQNWNTKHGSGALREL 173
LLRKNG G D K ++ D+L DP Y QN L
Sbjct 141 GEHTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------L 188
Query 174 TRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSE-QLDY---IESKRGVY 229
++L GG VD CG +G P+ +A+ G + TL++ ++D ++S R +
Sbjct 189 LKKLIGGDCIP-VDQYMCGKNGKPIADYAKIVAKEG--LTTLADIEVDVKSRMDSDRFI- 244
Query 230 CCRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQP-RV 288
+ + W R + Y QT F + S + D K P+ F + S++ ++ P +
Sbjct 245 VLNKKLYRVVWNVTRRNVPYSKQTAFTVVSVIQCDD-KESVPEHTFTIGSQILMVSPLKA 303
Query 289 EKKKTEGFMGRI-RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTE 347
K R+ + Y + Q+ ++ S + CN C +W T + ++ CG
Sbjct 304 TNNKNFNLKQRLLHTFYGKEAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGAN 363
Query 348 NLVIE-GPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGR--TR 404
+ + G +P NA+ CP + H+ A ++ + + + GG+ T
Sbjct 364 YSANDVDLQSSGLVPKNALFLANCPCANNGAC--SHNAAQVYSILDGKACVEVGGKSFTL 421
Query 405 CFGGCVFAYVGCYNKRAYWVPRASA-------DIGSGHTGITGDNVETLNEDLLEILSRE 457
FGG V+AY+GC + Y+VPRA + I +G TG VET N L +
Sbjct 422 TFGGVVYAYMGCCDGTMYFVPRAKSCVSRIGDAIFTGCTGTWDKVVETAN----LFLEKA 477
Query 458 RVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGN--YKVTKGK 515
+ ++N F L E ++LA S +TS F + S++ + + N + VT G
Sbjct 478 QHSLNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGD 534
Query 516 PVKGAWNIGQ----QRSVLTPLCGFPS------QAAGVIRSIFARTLDAANHSIPDLQRA 565
++ A NIG ++ P F + A + I + A ++ ++
Sbjct 535 YIRDAINIGANGVCNATINAPFIAFTGLGESFKKVAAIPWKICSNLKSALDYYCSNIMFR 594
Query 566 AV--TILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY-------VTGGLVQQTSQWLSNL 616
I +++ L+D T + S ++ Y V G + LS+
Sbjct 595 VFPYDIPCDVNDFVELLLDCGKLT---VATSYFVLRYLDEKFDTVLGTVSNACQTALSSF 651
Query 617 LGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVK-GQIQVASDNIKDCV 675
L V R A F+ D +++ K L+ ++ G + VA + K V
Sbjct 652 LNACVAASR-----------ATAGFISDMFKLFKVLMHKLYVYTSCGYVAVAEHSSK-IV 699
Query 676 KCFIDVVNKALEMCIDQVTIAGAKLRSL----------NLGEVFIAQSKGLYRQCIRGKE 725
+ +D+++KA+++ V+ AG KL ++ N G F +K Q +
Sbjct 700 QQVLDIMSKAMKLLHTNVSWAGTKLSAIIYEGREALLFNSGTYFCLSTKAKTLQ-----D 754
Query 726 QLQLLMPLKAPKEVTFL-----EGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
Q+ L++P K+ + D+ D S V + +G+LE P + IVG
Sbjct 755 QMNLVLPGDYNKKTLGILDPVPNADTIDVTANSTVVDVVHGQLE----PTNEHGPSMIVG 810
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
V V+ + + D+E Y G + + +FRLKGG P K VTFG+ EV Y++V
Sbjct 811 NYVLVSDKLFVRTDDEEFYPLCINGKVVS-TLFRLKGGMPSKKVTFGDVNTVEVTAYRSV 869
Query 841 RITFELDERVDKVL-NEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLD 899
IT+++ +D +L + K + +TVE V +F V+ + V+ L P+ G D++
Sbjct 870 SITYDIHPVLDALLSSSKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVE 929
Query 900 EWSVATFYLFDDAGEENFSSRMYCSFYP-----------------------PDEEEEDDA 936
++ Y+++ G+ +SS M S P DEE A
Sbjct 930 DFIDVPCYVYNQDGDCAWSSNMTFSINPVEDVEEVEEFIEDDYLSDELPIADDEEAWTRA 989
Query 937 ECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPE 996
E +D+ E E+D LPLE + E+V E E + D E E
Sbjct 990 VEEVMPLDDILVAEIELEED---LPLE--TALESVEAEVGES---ISDELCVVETAKAQE 1041
Query 997 PTPE 1000
P+ E
Sbjct 1042 PSVE 1045
Score = 124 bits (310), Expect = 6e-26, Method: Compositional matrix adjust.
Identities = 62/130 (48%), Positives = 84/130 (65%), Gaps = 0/130 (0%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ ++V + D ++ A V+VNAAN HLKHGGG+AGA+NKA+ G +Q+ESD+YI
Sbjct 1168 INNSVTLVLGDAIQIASLLPKCVLVNAANRHLKHGGGIAGAINKASGGDVQEESDEYISN 1227
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGI 1131
+GPL VG S LL G+ LA L VVGP+ ED LLK Y+ FN I++ PL+S+GI
Sbjct 1228 SGPLHVGDSVLLKGYGLADAILRVVGPDARNNEDAALLKRCYKTFNKHTIVVTPLISSGI 1287
Query 1132 FGAKPLQSLQ 1141
F P S +
Sbjct 1288 FSVDPKVSFE 1297
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 308 bits (789), Expect = 1e-81, Method: Compositional matrix adjust.
Identities = 233/757 (31%), Positives = 363/757 (48%), Gaps = 55/757 (7%)
Query 1381 KYKGIKIQEGI--VDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEA 1438
+ KG+ + I VD GV ++ Y++++ + +I N + MP GYVTHG +L ++
Sbjct 1364 RTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGC-PGICAMPFGYVTHGLDLAQS 1421
Query 1439 ARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSY-SGQRT 1497
+R +K P V ++S + + N + + +T E F+ V+ G Y W SG
Sbjct 1422 GNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGGYHSWHLVSGDLI 1479
Query 1498 ELGVEFLK----RGDKIVY-----HTLESPVEFHLDGEVLSLDKLKSLLSLREVK--TIK 1546
V + K G I Y + +++ V L+ ++ L+ R + I+
Sbjct 1480 VKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFS----DLEACRAYLTSRAAQQVNIE 1535
Query 1547 VFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRS 1606
V T+D N T +++ + T+ +Q G T+ G D++ P V G++ FV +D+ S
Sbjct 1536 VLVTIDGVNFRTVILNDATTFRKQLGATFYKGVDISDALPTVKMGGESLFV--ADNLSES 1593
Query 1607 EAF---EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQL 1663
E EYY T D +FL RY S ++WKF G+ S+K ++ NCY+++ ++ + L
Sbjct 1594 EEVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATIMMIDML 1653
Query 1664 -EVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE-SA 1721
++KF PALQ AY R + GD +F ALI+AY + T D + + LL A L SA
Sbjct 1654 HDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKAELTVSA 1713
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
K V C CG + TG+ A +Y G S + L++ + CVCG + LV+ + +
Sbjct 1714 KMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLVEHSTPW 1773
Query 1782 VMMSAPPAEYKLQQGT---FLCANEYTG-NYQCGHYTHITAKETL-YRIDGAHLTKMSEY 1836
+++S E K+ T + N + G GHY H+ K+ L Y+ D LTK S+
Sbjct 1774 LLVSGL-NEVKVSTSTDPVYRAFNVFQGVETSVGHYVHVRVKDGLFYKYDSGSLTKTSDM 1832
Query 1837 KGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQP-IDLVPTQ 1895
K +T V+Y + YT V Y LDGVT E+ P L YY KD YYT +P I P
Sbjct 1833 KCKMTSVWYPKVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKPTIKYSPAT 1892
Query 1896 PLPNASFDNFKLTCSNTKFADD-----LNQMTGF--TKPASRELSVTFFPDLNGDVVAID 1948
LP + + N L + D N + GF TKP S++L+ + P+ +GDV+ +
Sbjct 1893 ILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNEDGDVLLSE 1952
Query 1949 YRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVE 2008
+ +Y+ +KKG L KPI+W N KPN LR L+ P+ N + VL
Sbjct 1953 FNNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDNKYTVLQDN 2012
Query 2009 DTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTE---VVGNVILKPSDEGVKVTQ 2065
+Q + E P E+V +++IE K V GN GV V
Sbjct 2013 TSQLI-----EPNVPVVEDV---SITTRKLIEVKCKGLNKPFVKGNFSFVNDPNGVTVVD 2064
Query 2066 ELGHEDLMAAYVE-NTSITIKKPNELSLALGLKTIAT 2101
LG +L A YV+ NT + + N S L T+ +
Sbjct 2065 TLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVES 2101
Score = 177 bits (449), Expect = 5e-42, Method: Compositional matrix adjust.
Identities = 261/1084 (24%), Positives = 440/1084 (41%), Gaps = 152/1084 (14%)
Query 9 NEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEALSEAREHLK-NGTCGLVELE-KGVL 61
NEK HV ++P+ D+ L F D E A ++ LK G V + + +
Sbjct 22 NEKRSDHVACTVPLCDTEDMASKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRAM 80
Query 62 PQLEQPYVFIKRSDALSTNHGHKVVELVAEMD--GIQYGRSGIT---LGVLVPHVGETPI 116
L P V++ H +V +A D G R+ + LG+ P+
Sbjct 81 KFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDHVGAAMMRTTLNVKPLGMFFPYDSSLET 140
Query 117 AYRNVLLRKNGNKGAGGHSYGIDLKS---YDLGDELGTDPIEDYEQNWNTKHGSGALREL 173
LLRKNG G D K ++ D+L DP Y QN L
Sbjct 141 GEHTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------L 188
Query 174 TRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSE-QLDY---IESKRGVY 229
++L GG VD CG +G P+ +A+ G + TL++ ++D ++S R +
Sbjct 189 LKKLIGGDCIP-VDQYMCGKNGKPIADYAKIVAKEG--LTTLADIEVDVKSRMDSDRFI- 244
Query 230 CCRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQP-RV 288
+ + W R + Y QT F + S + D K P+ F + S++ ++ P +
Sbjct 245 VLNKKLYRVVWNVTRRNVPYSKQTAFTVVSVIQCDD-KESVPEHTFTIGSQILMVSPLKA 303
Query 289 EKKKTEGFMGRI-RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTE 347
K R+ + Y + Q+ ++ S + CN C +W T + ++ CG
Sbjct 304 TNNKNFNLKQRLLHTFYGKEAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGAN 363
Query 348 NLVIE-GPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGR--TR 404
+ + G +P NA+ CP + H+ A ++ + + + GG+ T
Sbjct 364 YSANDVDLQSSGLVPKNALFLANCPCANNGAC--SHNAAQVYSILDGKACVEVGGKSFTL 421
Query 405 CFGGCVFAYVGCYNKRAYWVPRASA-------DIGSGHTGITGDNVETLNEDLLEILSRE 457
FGG V+AY+GC + Y+VPRA + I +G TG VET N L +
Sbjct 422 TFGGVVYAYMGCCDGTMYFVPRAKSCVSRIGDAIFTGCTGTWDKVVETAN----LFLEKA 477
Query 458 RVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGN--YKVTKGK 515
+ ++N F L E ++LA S +TS F + S++ + + N + VT G
Sbjct 478 QHSLNFCQQFALTE---VVLAILSGTTSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGD 534
Query 516 PVKGAWNIGQ----QRSVLTPLCGFPS------QAAGVIRSIFARTLDAANHSIPDLQRA 565
++ A NIG ++ P F + A + I + A ++ ++
Sbjct 535 YIRDAINIGANGVCNATINAPFIAFTGLGESFKKVAAIPWKICSNLKSALDYYCSNIMFR 594
Query 566 AV--TILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY-------VTGGLVQQTSQWLSNL 616
I +++ L+D T + S ++ Y V G + LS+
Sbjct 595 VFPYDIPCDVNDFVELLLDCGKLT---VATSYFVLRYLDEKFDTVLGTVSNACQTALSSF 651
Query 617 LGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVK-GQIQVASDNIKDCV 675
L V R A F+ D +++ K L+ ++ G + VA + K V
Sbjct 652 LNACVAASR-----------ATAGFISDMFKLFKVLMHKLYVYTSCGYVAVAEHSSK-IV 699
Query 676 KCFIDVVNKALEMCIDQVTIAGAKLRSL----------NLGEVFIAQSKGLYRQCIRGKE 725
+ +D+++KA+++ V+ AG KL ++ N G F +K Q +
Sbjct 700 QQVLDIMSKAMKLLHTNVSWAGTKLSAIIYEGREALLFNSGTYFCLSTKAKTLQ-----D 754
Query 726 QLQLLMPLKAPKEVTFL-----EGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
Q+ L++P K+ + D+ D S V + +G+LE P + IVG
Sbjct 755 QMNLVLPGDYNKKTLGILDPVPNADTIDVTANSTVVDVVHGQLE----PTNEHGPSMIVG 810
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
V V+ + + D+E Y G + + +FRLKGG P K VTFG+ EV Y++V
Sbjct 811 NYVLVSDKLFVRTDDEEFYPLCINGKVVS-TLFRLKGGMPSKKVTFGDVNTVEVTAYRSV 869
Query 841 RITFELDERVDKVL-NEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLD 899
IT+++ +D +L + K + +TVE V +F V+ + V+ L P+ G D++
Sbjct 870 SITYDIHPVLDALLSSSKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVE 929
Query 900 EWSVATFYLFDDAGEENFSSRMYCSFYP-----------------------PDEEEEDDA 936
++ Y+++ G+ +SS M S P DEE A
Sbjct 930 DFIDVPCYVYNQDGDCAWSSNMTFSINPVEDVEEVEEFIEDDYLSDELPIADDEEAWTRA 989
Query 937 ECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPE 996
E +D+ E E+D LPLE + E+V E E + D E E
Sbjct 990 VEEVMPLDDILVAEIELEED---LPLE--TALESVEAEVGES---ISDELCVVETAKAQE 1041
Query 997 PTPE 1000
P+ E
Sbjct 1042 PSVE 1045
Score = 124 bits (310), Expect = 5e-26, Method: Compositional matrix adjust.
Identities = 62/130 (48%), Positives = 84/130 (65%), Gaps = 0/130 (0%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ ++V + D ++ A V+VNAAN HLKHGGG+AGA+NKA+ G +Q+ESD+YI
Sbjct 1168 INNSVTLVLGDAIQIASLLPKCVLVNAANRHLKHGGGIAGAINKASGGDVQEESDEYISN 1227
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGI 1131
+GPL VG S LL G+ LA L VVGP+ ED LLK Y+ FN I++ PL+S+GI
Sbjct 1228 SGPLHVGDSVLLKGYGLADAILRVVGPDARNNEDAALLKRCYKTFNKHTIVVTPLISSGI 1287
Query 1132 FGAKPLQSLQ 1141
F P S +
Sbjct 1288 FSVDPKVSFE 1297
>sp|P36697|R1AB_CVCAI Replicase polyprotein 1ab (Fragment) OS=Canine
coronavirus (strain Insavc-1) OX=36391 GN=rep PE=4 SV=1
Length=168
Score = 179 bits (455), Expect = 7e-50, Method: Compositional matrix adjust.
Identities = 87/166 (52%), Positives = 117/166 (70%), Gaps = 2/166 (1%)
Query 6909 PRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAF 6968
P TK + EN SK+GFFTY+ GFIK+KL+LGGS A+KITE SWN DLY+L+ F +WT F
Sbjct 1 PNTKSIDGENTSKDGFFTYVNGFIKEKLSLGGSAAIKITEFSWNKDLYELIQRFEYWTVF 60
Query 6969 VTNVNASSSEAFLIGANYLGK--PKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFP 7026
T+VN SSSE FLIG NYLG + +DG MHANYIFWRN+ + LS S+ D KF
Sbjct 61 CTSVNTSSSEGFLIGVNYLGPYCDRAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFK 120
Query 7027 LKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
+ +++LKE ++N+M+ LL+KG+L+IR N +++ + LVN
Sbjct 121 CRCNNALIVNLKEKELNEMVIGLLKKGKLLIRNNGKLLNFGNHLVN 166
>sp|Q04158|R1AB_CVPR8 Replicase polyprotein 1ab (Fragment) OS=Porcine
respiratory coronavirus (strain 86/137004 / isolate
British) OX=33736 GN=rep PE=4 SV=1
Length=131
Score = 128 bits (322), Expect = 2e-32, Method: Composition-based stats.
Identities = 61/129 (47%), Positives = 84/129 (65%), Gaps = 2/129 (2%)
Query 6946 ITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGK--PKEQIDGYTMHANY 7003
ITE SWN LY+L+ F +WT F T+VN SSSE FLIG NYLG K +DG MHANY
Sbjct 1 ITEFSWNKYLYELIQRFEYWTVFCTSVNTSSSEGFLIGVNYLGPYCDKAIVDGNIMHANY 60
Query 7004 IFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRV 7063
IFWRN+ + LS S+ D KF + +++LKE ++N+M+ LL KG+L+IR N ++
Sbjct 61 IFWRNSTIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVIGLLRKGKLLIRNNGKL 120
Query 7064 VVSSDILVN 7072
+ + +N
Sbjct 121 LNFGNHFIN 129
>sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11156
GN=rep PE=1 SV=1
Length=6857
Score = 135 bits (340), Expect = 2e-29, Method: Compositional matrix adjust.
Identities = 139/577 (24%), Positives = 251/577 (44%), Gaps = 52/577 (9%)
Query 4788 FYDFAVSKGFFKEGSSV--ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVV 4845
FYD + + G K+F++ + A++D YY Y + L V + +
Sbjct 4909 FYDVGLCQELTDAGVDCGEAFKYFYYLSNPAGALADVCYYDYQGTGFYSPKLLAGVYDFM 4968
Query 4846 DKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWG-KARLYYDSMSYEDQDALFAYTKRNV 4904
+ +CY IN + + N G + Y ++ E+ LF Y ++
Sbjct 4969 KRVTECYR---INERFTYEQAKPRKSSMGINITGYQQDAVYRALGPENIARLFEYAQKAP 5025
Query 4905 IPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKL---LKSIAATRGATVVIGTS 4961
+P T++ K+A+SAK RARTV+ S ++ R H+ + + +A G +IG S
Sbjct 5026 LPFCTKIITKFALSAKARARTVSSCSFIASTIFRFAHKPVTSKMVEVAQNSGGFCLIGVS 5085
Query 4962 KFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRF 5021
K+ + LK Y +E + G DY KCDR P R + + +L +
Sbjct 5086 KYGLKFSKFLKDKYGAIEGFDVFGSDYTKCDRTFPLSFRALTAALLYE----LGEWDEKS 5141
Query 5022 YRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLS--T 5079
+ NE + + ++C G L KPGGTSSGDATTA++N+ +N +LS +
Sbjct 5142 WLYLNEVNSYMLDTMLCDGMLLNKPGGTSSGDATTAHSNTFYNYMVHYVVAFKTILSDLS 5201
Query 5080 DGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNY 5139
+GNK+ +R H Y + V + +++ + + ++ + LSDD+ + ++
Sbjct 5202 EGNKV----MRIAAHNAYTT--GDYQVFNTLLEDQF---QTNYFLNFLSDDSFI-FSKPE 5251
Query 5140 AAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGP-HEFCSQHTMLVKQGDDYVYL 5198
A + + + +NF L + + + K W+ TKG EFCS H ++K +Y +L
Sbjct 5252 ALK--IFTCENFSNKLQTILHTKVDQTKSWS----TKGHIEEFCSAH--IIKTDGEYHFL 5303
Query 5199 PYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIR 5258
P R+L + +D + D M RFV++ ++ +++ + + +F ++L ++
Sbjct 5304 --PSRGRLLASLLILDKLSDVDIYYM--RFVAILCESAVYSRYQPEFFNGLFQVFLDKVQ 5359
Query 5259 KLH-----DELTGHML--DMYSVMLTNDNTSR-----YWEPEFYEAMYTPHTVLQAVGAC 5306
+ D +L + Y ++ N+ Y E + + V C
Sbjct 5360 QFRKDYCCDPCPPQLLEREFYENLVFTSNSEVGIVDCYLENFKLQCEFKQQANFDKV--C 5417
Query 5307 VLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLV 5343
C + C C LC C Y HV+ ++H V
Sbjct 5418 FCCPNPAVSVCEECYVPLPLCAYCYYVHVVISNHSKV 5454
Score = 92.8 bits (229), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 99/376 (26%), Positives = 169/376 (45%), Gaps = 60/376 (16%)
Query 6617 QLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSH--GQL 6674
+LP+T F+ R L + + + +LA++ + H+ GDF+ +
Sbjct 6450 ELPDTLFSTGR-LYNLDHDAAQNFNVKQLAIETMPNNH--------HVFSGDFTEVGTDI 6500
Query 6675 GGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDA----QTGSSKCVCSVIDLLLDD 6730
GG+H ++ L S + NY A G + +++D+ +
Sbjct 6501 GGVHHVVALNGYK-------------GSIIPNYVKPIATGLINVGRAVKRTTLVDVCANQ 6547
Query 6731 FVEIIKSQDLSV-ISKVVKVTIDYAEISFMLWCK-DGHVETFYPKLQASQAWQPGVAMPN 6788
E +K Q V +SKV+ V ID+ ++ FM++ + ++TFYP+ +++ PN
Sbjct 6548 LYEKVKQQLEGVKVSKVIFVNIDFQDVQFMVFANGEDDIQTFYPQKDFVRSY---YEWPN 6604
Query 6789 LYKMQRMLLEKCDLQNYGEN-AVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGA 6847
+ + DL+NYG+N +P+ + N AKYTQ+C ++ + V N V H GA
Sbjct 6605 ILP---QIESHYDLKNYGQNPTFMPQPV--NFAKYTQICTFIQD-HVKVARNALVWHLGA 6658
Query 6848 GSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY 6907
G +PG VL + L+ D+ D+ STL+ D + + +LI+SD+Y
Sbjct 6659 AGVDGCSPGDIVLSSFFKE-CLVYSWDIKDY-----STLL-DKHSYDCNFRPNLIVSDIY 6711
Query 6908 DPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSW-NADLYKLMGHFSWWT 6966
+ + +D +LALGG+I K TE S + L + +FS
Sbjct 6712 NVSSNVSEVLDDC------------VHRLALGGTIVFKTTESSRPDIQLSQFTKYFSAVQ 6759
Query 6967 AFVTNVNASSSEAFLI 6982
F VN SSSE F++
Sbjct 6760 FFTAGVNTSSSEVFVV 6775
Score = 65.5 bits (158), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 51/182 (28%), Positives = 85/182 (47%), Gaps = 13/182 (7%)
Query 962 LEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQF----TGYLKLTDNVA 1017
L+ G+ E V V+ + +++ + E+ E + P E +F T + + D+
Sbjct 1641 LDIGSQCERVFVDYDVKKNEWTLSPEEGEDSDDNLDLPFEQYYEFKIGQTNVVLVQDDFK 1700
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ +K Q + +VN AN LKHGGG+A ++ +Q S++YI N + V
Sbjct 1701 -SVFEFLKSEQGVD--YVVNPANSQLKHGGGIAKVISCMCGPKLQAWSNNYITKNKTVPV 1757
Query 1078 GGSCLLSGHNLAKKC--LHVVGPNLNAGEDIQLLKAAYENF----NSQDILLAPLLSAGI 1131
+ G L KK +H VGP ++ G+ Q L A+ + Q +L +LS GI
Sbjct 1758 TKAIKSPGFQLGKKVNIIHAVGPRVSDGDVFQKLDQAWRSVFDLCEDQHTILTSMLSTGI 1817
Query 1132 FG 1133
FG
Sbjct 1818 FG 1819
Score = 50.4 bits (119), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 37/103 (36%), Positives = 54/103 (52%), Gaps = 11/103 (11%)
Query 6085 FVLWAHGFELTSMKYFVKIGPERTC--CLCDKRATCFSTSSDTYACWNHSVGF--DYVYN 6140
F+L++ +L S+K++V+ TC C C + A C + Y C N G + N
Sbjct 6077 FILYSCSNDLKSLKFYVEFD---TCYFCSCGEMAICLMRDGN-YKCRNCYGGMLISKLVN 6132
Query 6141 PFMIDVQQWGFTGNLQSNHDQHCQ-VHGNAHVASCDAIMTRCL 6182
+DVQ+ LQ HD CQ HG++H A CDA+MT+CL
Sbjct 6133 CKYLDVQKERV--KLQDAHDAICQQFHGDSHEALCDAVMTKCL 6173
Score = 46.6 bits (109), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 48/178 (27%), Positives = 78/178 (44%), Gaps = 19/178 (11%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSA--RIVYTACSHAAVDALCEKALKYLPIDKCSRIIPAR 5638
+ GPPGTGK+ F L S+ R VY A +H V + EK +D +
Sbjct 5665 VMGPPGTGKTTFVYDTYLSKASSSNRFVYCAPTHRLVGDMDEK------VDGAVVVSAYN 5718
Query 5639 ARVECFDKFKVNSTLEQY--VFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
R + V + + Y + CT N LP + +++ DE+S+ + + + + K
Sbjct 5719 DRTY---RNPVWNKDDSYGVLLCTHNTLPFIKSAVLIADEVSLIPPHVMIKI-LSMGFKK 5774
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVS 5754
V +GDP QL +P K + + F L++ +L C RCP +I+ S
Sbjct 5775 VVLLGDPFQL-SPVYKNHKVHFKYDTF----YLLQLATQKRYLTACYRCPPQILSAFS 5827
Score = 41.6 bits (96), Expect = 0.42, Method: Compositional matrix adjust.
Identities = 35/110 (32%), Positives = 50/110 (45%), Gaps = 21/110 (19%)
Query 4485 RQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVEN---PDIL 4541
R +++++ DLVYA+ G+ D L E +N D++ + + F+ N P IL
Sbjct 4662 RGPTSQWSLGDLVYAIWL---GDQDYLSECGFVFNPSRDEFLDDANQRSFLANLLEPAIL 4718
Query 4542 RVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDF 4591
N Q V+ C LTLDN DLNG YDFGD+
Sbjct 4719 ----NFSHIYWQ-----VKMCKVPYK------LTLDNVDLNGQLYDFGDY 4753
>sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream
virus (isolate Blicca bjoerkna L./Germany/DF24/00) OX=766180
GN=rep PE=1 SV=1
Length=6872
Score = 130 bits (328), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 144/646 (22%), Positives = 265/646 (41%), Gaps = 90/646 (14%)
Query 4784 FNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNA--AISDYDYYRYNLPTMCDIRQLLFV 4841
+ + FYD + + G ++ + Q G A+ D+ YY YN P D L V
Sbjct 4888 YKRPFYDLDLIQRMNSAGLNLSETTGYHYQCGTTTEAVEDFMYYNYNSPKSFDPSYLKSV 4947
Query 4842 VEVV-DKYFDCYDGGCINANQVIVNNLDKSAGFP-FNKWGKA------RLYYDSMSYEDQ 4893
+ DK+ I+ ++ L+ +G P + G + ++++ +
Sbjct 4948 YTYMRDKFMKI-----ISTDE----KLNHQSGAPRMSSMGVGVSGFFQKTVWNALPEDFS 4998
Query 4894 DALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRG 4953
L + V+P T + K+ K R RT+ G S ++ R H+ + + T
Sbjct 4999 PRLLDTASKTVMPFSTNIVKKFQRQKKTRVRTLGGSSFITSSIFRMLHKPVTNKMVQTAQ 5058
Query 4954 ATV---VIGTSKFYGGWHNMLKTVYSD-VETPHLMGWDYPKCDRAMPNMLRIMASLVLAR 5009
A + +IG SKF G+H L + + +E +MG DY KCDR+ P + R +++ +
Sbjct 5059 ANIGPFLIGISKFNLGFHKYLSAHHPNGIEDCQVMGADYTKCDRSFPVVCRALSAALFYE 5118
Query 5010 KHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAV 5069
+L + NE L + G ++ KPGGT+SGD+TTA++NS +N +
Sbjct 5119 ----LGHLEPNNHWFLNEMFAFLLDPSFISGHIFNKPGGTTSGDSTTAFSNSFYNYFVHL 5174
Query 5070 TANVNALLSTDGNKIADKYVRNLQHRLYEC-LYRNRDVDHEFVDEFYAYLRKHFSMMILS 5128
L+T+ + + + NL H+ + D+ D+ + + + LS
Sbjct 5175 YIQYLTFLTTEMPP-SYQPLCNLAHQAFSTGNTETYDLYFSMADDLNS---TEYFLHFLS 5230
Query 5129 DDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTML 5188
DD+ + + + + NF L ++ AK W+ HEFCS H
Sbjct 5231 DDSFII---SKPTAFPIFTPANFSMKLQNVLGCYVDPAKSWSADGEI---HEFCSSHICK 5284
Query 5189 VKQGDDYVYLPYPDPSRIL-GAGC---------FVDDIVKTDGTLMIERFVSLAIDAYPL 5238
+ + YV PDP+ +L G C + +V T L + FV+ +
Sbjct 5285 INEKYQYV----PDPNNMLAGLICAPEPTPQDKLIWKLVATCAELAVFHFVNPTL----- 5335
Query 5239 TKHPNQEYADVFHLYLQYIRKLHDELTGHM-----------LDMYSVMLTNDNTSRYWEP 5287
+ ++FHL ++ LH E +D Y+ ++ +++ +Y
Sbjct 5336 -------FNNIFHL----LQSLHAEFVSEHSVNLLPPKLLEIDFYTDLIDSEDVEQY--S 5382
Query 5288 EFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVN 5347
+ + + ++Q+ C C++ T C C + +C C Y+H++ T H +
Sbjct 5383 FLADTLTEKNIIMQSASQCYFCDNATVSTCSDCTVQYPMCAHCAYEHLMLTDHTPTQVLP 5442
Query 5348 PYVCNAPGCDVTDVTQL----YLGGMSYYCKSHKPPISFPLCANGQ 5389
+V CD TD L +G + C +H ++ PL + +
Sbjct 5443 CHV-----CDQTDPRHLNHTFVMGTVKVACDNHVEGMALPLVDHAR 5483
Score = 82.8 bits (203), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 89/341 (26%), Positives = 142/341 (42%), Gaps = 50/341 (15%)
Query 6662 EHIVYGDFSHGQ--LGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKC 6719
H+ GD S+ +GG+H++ + + P + ++ I A +K
Sbjct 6496 HHVSVGDTSNVSWTIGGMHVLTAFQNITNYQLVSG----PANPIMR---INVALERGNKV 6548
Query 6720 VCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCK-DGHVETFYPKLQAS- 6777
+ +D L D+ +I + ++V SK T+D + M + DG ++T YP QA
Sbjct 6549 ETTALDTTLQDYYKIATTNKVTV-SKTTFFTLDGGQYRMMNFANPDGTIQTSYPVAQAQS 6607
Query 6778 ------QAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIM--MNVAKYTQLCQYL 6829
+ + + P + E D PK +N+ KY Q+C L
Sbjct 6608 QLITNYRIYPSYITWPTFFTN-----EATDCWAIPNYNAPPKNQTCNINIQKYDQMCD-L 6661
Query 6830 NTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGD 6889
+ L +P + H G +K +PG VLRQ+ L DL + VSD
Sbjct 6662 FAIDLKIPVKGHIHHLGNAGNK-YSPGDVVLRQYFDQAHL-TSYDLREVVSD-------- 6711
Query 6890 CATVHTANKWD--LIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKIT 6947
+H ++W I+SD+Y P T F + +++ L LGGSI K+T
Sbjct 6712 IPVLHPNDEWKAHFILSDVYAPDT-----------DFTSLALEYMQNHLRLGGSIMWKMT 6760
Query 6948 EHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLG 6988
E S + +++ +F W A VN SSSE FL A Y G
Sbjct 6761 ETSI-LQVNEIVKYFGSWKAVTFAVNYSSSETFLFCAGYTG 6800
Score = 60.5 bits (145), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 76/312 (24%), Positives = 118/312 (38%), Gaps = 44/312 (14%)
Query 4284 AITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLR 4343
AI+ P + ++ G S C C DH C G +VQIP ++ F L
Sbjct 4468 AISQVPVQTIGYLTYAGISVCRQCATKQDHT-----CQYAGYFVQIPREHVSN--IFNLT 4520
Query 4344 NTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSA-ARLTPCGTG---TSTDV 4399
+T C K +C L++ + + G++ P TG S+
Sbjct 4521 DT--PPCLHNKFTCTTCQPLQQQSKTQQPPLNLVGQCLGLTLDTAFCPFQTGEYKPSSRE 4578
Query 4400 VYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLV 4459
Y +I N VA K K N ++ L D+ HE IY +
Sbjct 4579 FY--INILNNNVASLRKVFKKNTASIPSENGTIMLKDT----------GTAHE--IY-VA 4623
Query 4460 KDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYN 4519
K A + R + D ++ R T Y++ DLVYA D K +L+ +
Sbjct 4624 KQLLAKGLPVLQHARFNHDGTDYLIRYYTTPYSLGDLVYAYMVGD------FKHMLLALD 4677
Query 4520 CCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQ 4579
D+ + ++ Y N E++R L + + + A + +TLDN
Sbjct 4678 ITDETCLDPGNY----------SSYYNFKEQLRNKLASVIPNVNKILAAELPLAITLDNI 4727
Query 4580 DLNGNWYDFGDF 4591
DLNG YDFGD+
Sbjct 4728 DLNGFLYDFGDY 4739
Score = 52.4 bits (124), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 38/112 (34%), Positives = 56/112 (50%), Gaps = 12/112 (11%)
Query 6081 DRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACW-NHSVGFDY-- 6137
+RVV+VL+ G +L ++ +G + TC C K AT ++ + + NH +
Sbjct 6074 NRVVYVLYGAGNDLRALTNLNIVG-DYTCEKCTKEATFYTIHREIVHTFCNHHAPSQFPL 6132
Query 6138 --VYNPFMIDVQQWGFTGNLQSNHDQHCQV----HGNAHVASCDAIMTRCLA 6183
N ID+Q + N QS + H +V HG+AH AS D IMT CLA
Sbjct 6133 MGTINAQAIDIQHA--SANKQSLTNTHAEVCNQQHGDAHTASADTIMTGCLA 6182
Score = 50.8 bits (120), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 66/302 (22%), Positives = 126/302 (42%), Gaps = 25/302 (8%)
Query 5575 MQKYSTLQGPPGTGKSHFAIG--LALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS 5632
++K + + GPPGTGK+ + + + P+ ++ Y A +H V ++ +
Sbjct 5641 LKKATFIIGPPGTGKTTYVMKNFIDTASPANKVAYIAPTHKLVQSMDQAIWDKYNHTVSV 5700
Query 5633 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5692
++ + ++ + +NS + + T A+ ++FDE++++ + + +
Sbjct 5701 SVVKSELNNNKYN-YPLNSATKTIMLGTPGAVCTHAGCTLIFDEVTLSQLNTIINAISVV 5759
Query 5693 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5752
+ +++GDP QL P T + +L Y N L + L C RCP+ I
Sbjct 5760 KPSQVIFLGDPLQL-GPVTHM--RSLSYSYTN--FPLFQFCNDSRVLSICYRCPSNI--- 5811
Query 5753 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVF 5812
++ +K + D + + G VS + P + L RN + V
Sbjct 5812 -----FNLWVKPYTDSNVRIDPHAAGGDAKIIVSDQCSNPDAYQYVQKLARNNPDK--VL 5864
Query 5813 ISPYNSQNAVASKILGLPTQ-TVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKI 5871
+ Y I+GL T+DSSQG Y + I T + +NR VA++R+
Sbjct 5865 LCNYKK------PIIGLENAVTIDSSQGKTYKHTIVVLLGNTNFTQVINRAIVAMSRSTH 5918
Query 5872 GI 5873
I
Sbjct 5919 SI 5920
>sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus
1 OX=360393 GN=rep PE=2 SV=1
Length=6733
Score = 127 bits (319), Expect = 5e-27, Method: Compositional matrix adjust.
Identities = 132/553 (24%), Positives = 234/553 (42%), Gaps = 48/553 (9%)
Query 4806 LKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVN 4865
K+F++ + A++D +Y Y + L V + + + CY +
Sbjct 4805 FKYFYYLSNPAGALADVCFYDYQGTGFYSPKLLAGVYDFMKRVTTCYK---TDERFTYEQ 4861
Query 4866 NLDKSAGFPFNKWG-KARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRAR 4924
+ + N G + Y ++ E+ LF Y ++ +P T++ K+A+SAK RAR
Sbjct 4862 AKPRKSSMGINITGYQQDAVYRALGPENITKLFEYAQKAPLPFCTKIITKFALSAKARAR 4921
Query 4925 TVAGVSICSTMTNRQFHQKL---LKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETP 4981
TV+ S ++ R H+ + + +A +IG SK+ + LK Y +E
Sbjct 4922 TVSSCSFIASTIFRFAHKPVTSKMVEVAQNSQGFCLIGVSKYGLKFSKFLKDKYGAIEQF 4981
Query 4982 HLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGS 5041
+ G DY KCDR P R + + +L + NE + + ++C G
Sbjct 4982 DVFGSDYTKCDRTFPLSFRALTAALLYELGG----WEEDSWLYLNEVNSYMLDTMLCDGM 5037
Query 5042 LYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLS--TDGNKIADKYVRNLQHRLYEC 5099
L KPGGTSSGDATTA++N+ +N +LS +D NK+ +R H Y
Sbjct 5038 LLNKPGGTSSGDATTAHSNTFYNYMVHYVVAFKTILSDLSDCNKV----MRIAAHNAYTT 5093
Query 5100 LYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGL--VASIKNFKAVLYY 5157
+ V + ++E + + ++ + LSDD+ + ++ G + + +NF L
Sbjct 5094 --GDYGVFNTLLEEQF---QTNYFLNFLSDDSFI-----FSKPGALKIFTCENFSNKLQT 5143
Query 5158 QNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIV 5217
+ + K W T + EFCS H ++K +Y +L P R+L + +D +
Sbjct 5144 ILHTKVDLTKSWATTGHIE---EFCSAH--IIKTDGEYHFL--PSRGRLLASLLILDKLS 5196
Query 5218 KTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLH-----DELTGHMLD-- 5270
D M RFV++ ++ +++ + + +F ++L +++ D +LD
Sbjct 5197 DVDIYYM--RFVAILCESAVYSRYQPEFFNGLFQVFLDKVQQFRKDYCCDPCPTQLLDRQ 5254
Query 5271 MYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVG---ACVLCNSQTSLRCGACIRRPFLC 5327
Y ++ NT + E Q G C C + C C LC
Sbjct 5255 FYENLVFTSNTEVGLVDCYLENFKLQCEFKQQAGFDRVCFCCPNPAVSVCEECYVPLPLC 5314
Query 5328 CKCCYDHVISTSH 5340
C Y HV+ +SH
Sbjct 5315 AYCYYVHVVISSH 5327
Score = 92.8 bits (229), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 102/385 (26%), Positives = 174/385 (45%), Gaps = 74/385 (19%)
Query 6615 IQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSH--G 6672
+++LPET F+ R L + + + +LA++ + + H+ GDF+
Sbjct 6324 LRELPETLFSTGR-LYNLEHDPSKNFNVQQLAIETIPKNH--------HVFAGDFTDVGT 6374
Query 6673 QLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDA----QTGSSKCVCSVIDLLL 6728
+GG+H ++ L S + NY A G S +++D+
Sbjct 6375 DIGGVHHVVALNGYK-------------GSIIPNYVKPIATGLINVGRSVKRTTLVDVCA 6421
Query 6729 DDFVEIIKSQDLSV-ISKVVKVTIDYAEISFMLWCK-DGHVETFYPKLQASQAWQPGVAM 6786
+ E +K Q V +SKV+ V ID+ E+ FM++ K + ++TFYP+ + +++
Sbjct 6422 NQLYEKVKQQIAGVKVSKVIFVNIDFQEVQFMVFAKGEDDIQTFYPQKEFIRSY------ 6475
Query 6787 PNLYKMQRMLLE---KCDLQNYGENA-VIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRV 6842
Y+ +L E DL+NYG++ +P+ + N AKYTQ+C ++ + V N +
Sbjct 6476 ---YEWPTILPELESHYDLKNYGQDPQFMPQPV--NFAKYTQICTFIQE-HVKVARNSLI 6529
Query 6843 IHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIG----DCATVHTANK 6898
H GA G +PG VL + L+ D+ D+ TL+ DC +
Sbjct 6530 WHVGAAGIDGCSPGDIVLSSFFKE-CLVYSWDVKDY-----DTLLEKHNYDCNF-----R 6578
Query 6899 WDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSW-NADLYK 6957
+LI+SD+Y+ + D +LALGG+I K TE S + L K
Sbjct 6579 PNLIVSDVYNVSSNVSEVLEDC------------VHRLALGGTIIFKTTESSRPDIQLSK 6626
Query 6958 LMGHFSWWTAFVTNVNASSSEAFLI 6982
+ +F+ F VN SSSE F++
Sbjct 6627 VTKYFAAVHFFTAGVNTSSSEVFVV 6651
Score = 62.4 bits (150), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 51/184 (28%), Positives = 85/184 (46%), Gaps = 17/184 (9%)
Query 962 LEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGY------LKLTDN 1015
L+ G+S E V V+ + ++ D +T ++ + E P NQ+ + + L +
Sbjct 1595 LDVGSSLEQVYVDYDVSKNVWDLSTH---LQDDSSDDLELPFNQYYEFKVGRASVVLVQD 1651
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPL 1075
D +K Q + +VN AN LKHGGG+A ++ + S++YIK L
Sbjct 1652 DFKSVYDFLKSEQGVD--YVVNPANNQLKHGGGIAKVISCMCGPKLTSWSNNYIKQYKKL 1709
Query 1076 TVGGSCLLSGHNLAK--KCLHVVGPNLNAGEDIQLLKAA----YENFNSQDILLAPLLSA 1129
V + G L K + +HVVGP + + L+A+ ++N +L +LS
Sbjct 1710 GVTCAIRSPGFQLGKGVQIIHVVGPKSADSDVVNKLEASWRSVFQNVKPDTTVLTSMLST 1769
Query 1130 GIFG 1133
GIFG
Sbjct 1770 GIFG 1773
Score = 52.4 bits (124), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 48/176 (27%), Positives = 79/176 (45%), Gaps = 15/176 (9%)
Query 5581 LQGPPGTGKSHFAIG--LALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPAR 5638
+ GPPGTGK+ F L+ PS R VY A +H V + EK +D +
Sbjct 5541 VMGPPGTGKTTFVYNTYLSKASPSNRFVYCAPTHRLVGDMDEK------VDGAVVVSAYN 5594
Query 5639 ARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYV 5698
R +K + + + + CT N LP + +++ DE+S+ + + + + K V
Sbjct 5595 DRTYRNPVWKKDDSYD-VLLCTHNTLPFIKSAVLIVDEVSLIPPHVMIKI-LSMGFKKVV 5652
Query 5699 YIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVS 5754
+GDP QL +P K + + F L++ +L C RCP +I+ S
Sbjct 5653 LLGDPFQL-SPVYKNHKVHFKYDTF----YLLQLATQKRYLTACYRCPPQILSAFS 5703
Score = 52.0 bits (123), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 35/101 (35%), Positives = 53/101 (52%), Gaps = 7/101 (7%)
Query 6085 FVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWN--HSVGFDYVYNPF 6142
F+L++ +L S+K++V+ G C C + A C Y C N ++ + N
Sbjct 5953 FILYSCSNDLKSLKFYVEFGTNYFCS-CGELAICL-MRDGLYKCRNCYGNMSISKLVNCK 6010
Query 6143 MIDVQQWGFTGNLQSNHDQHCQ-VHGNAHVASCDAIMTRCL 6182
+DVQ+ LQ HD CQ HG++H A CDA+MT+CL
Sbjct 6011 YLDVQKERI--KLQDAHDAICQQFHGDSHEALCDAVMTKCL 6049
Score = 39.3 bits (90), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 47/189 (25%), Positives = 80/189 (42%), Gaps = 34/189 (18%)
Query 4405 DIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDC-- 4462
D+ E AG K K+N + K + F++KR QHE + L +
Sbjct 4473 DLATEYNAGIVKVNKSNTHSVEYKGQR-------FMIKR---VKDQHE---FALARTAFL 4519
Query 4463 PAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCD 4522
P++ H + +V R T++++ DLVYA+ D+ D E +N
Sbjct 4520 PSIIPHHMVHQNGEWFLV----RGPTTQWSLGDLVYAIWLGDQAYLD---ECGFVFNPSR 4572
Query 4523 DDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLN 4582
D++ + + ++ ANL E ++L + ++ + +TLDN DL
Sbjct 4573 DEFLDDANQRSYL---------ANLLE---PAILSFCEIFHCVKGCQVPYKITLDNLDLK 4620
Query 4583 GNWYDFGDF 4591
G YDFGD+
Sbjct 4621 GQLYDFGDY 4629
Score = 38.1 bits (87), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 37/148 (25%), Positives = 69/148 (47%), Gaps = 16/148 (11%)
Query 3024 VVAGGIIAILVTCAAYYFMKFRRV-------FGEYNHVVAANALLFLMSFTILCLVPAYS 3076
+++ + +LV F+ R+ F + +VV LLF+ + +L +V
Sbjct 2937 IISPYVFVVLVAIFTIVFLFLLRMYIVMYSYFKVFTYVVFK--LLFVNTVMVLFVVCLPP 2994
Query 3077 FLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNN 3136
+PGV V L+L + V FL +L ++F I+P++ ++V + W +
Sbjct 2995 LVPGVVFVLALWL----CDSVVFLLYLAVLSLF--ILPWFYVMLFVLIVGGFVFWWMMKS 3048
Query 3137 YLRKRVMFNGVTFS-TFEEAALCTFLLN 3163
+ +G+TF+ TFE+ + C F LN
Sbjct 3049 SDVVHLTPDGLTFNGTFEQVSKCVFPLN 3076
>sp|Q97UU4|Y2899_SACS2 Uncharacterized protein SSO2899 OS=Saccharolobus
solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322
/ P2) OX=273057 GN=SSO2899 PE=4 SV=1
Length=177
Score = 68.2 bits (165), Expect = 7e-11, Method: Composition-based stats.
Identities = 45/106 (42%), Positives = 61/106 (58%), Gaps = 8/106 (8%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN +L+HGGGVA A+ + +QKESD+Y+K GP+ VG + S L AK +
Sbjct 25 IVNAANSYLQHGGGVAYAIVRKGGYIIQKESDEYVKKFGPVPVGEVAVTSAGKLKAKYVI 84
Query 1094 HVVGPNLN-AGEDIQLLKAAYENFNSQDIL-----LAPLLSAGIFG 1133
H VGP GED +L A +++ D L P +S GI+G
Sbjct 85 HAVGPRYGIEGED-KLESAIFKSLLKADELSLSSIAMPAISTGIYG 129
>sp|Q8ZXT3|Y1111_PYRAE Uncharacterized protein PAE1111 OS=Pyrobaculum
aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630
/ CIP 104966 / NBRC 100827 / IM2) OX=178306 GN=PAE1111 PE=4
SV=1
Length=182
Score = 68.2 bits (165), Expect = 9e-11, Method: Composition-based stats.
Identities = 42/106 (40%), Positives = 63/106 (59%), Gaps = 8/106 (8%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN +L+HGGGVAGA+ + +Q+ES ++++ +GP+ VG + S L AK +
Sbjct 25 IVNAANSYLEHGGGVAGAIVRKGGQVIQEESREWVRKHGPVPVGDVAVTSAGRLKAKYVI 84
Query 1094 HVVGPNLNAGEDIQLLKAAYEN--FNSQDILLA----PLLSAGIFG 1133
H VGP E I+ L A +N ++++ L P +S GIFG
Sbjct 85 HAVGPRCGV-EPIEKLAEAVKNALLKAEELGLVSIALPAISTGIFG 129
>sp|Q9WYX8|Y508_THEMA Uncharacterized protein TM_0508 OS=Thermotoga
maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC
100826 / MSB8) OX=243274 GN=TM_0508 PE=3 SV=1
Length=599
Score = 72.4 bits (176), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 50/136 (37%), Positives = 73/136 (54%), Gaps = 13/136 (10%)
Query 1022 DIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSC 1081
DI +E A IVNAAN +LKHGGGVAGA+ +A +Q+ESD ++ G + G +
Sbjct 435 DITREEVDA----IVNAANEYLKHGGGVAGAIVRAGGSVIQEESDRIVQERGRVPTGEAV 490
Query 1082 LLSGHNL-AKKCLHVVGP---NLNAGEDIQLLKAAYEN-FNSQDILLA----PLLSAGIF 1132
+ S L AK +H VGP + GED L KA Y + ++ L P +S GIF
Sbjct 491 VTSAGKLKAKYVIHTVGPVWRGGSHGEDELLYKAVYNALLRAHELKLKSISMPAISTGIF 550
Query 1133 GAKPLQSLQVCVQTVR 1148
G +++ + + +R
Sbjct 551 GFPKERAVGIFSKAIR 566
>sp|Q4J9D2|Y1252_SULAC Uncharacterized protein Saci_1252 OS=Sulfolobus
acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929
/ NBRC 15157 / NCIMB 11770) OX=330779 GN=Saci_1252 PE=4
SV=1
Length=181
Score = 67.8 bits (164), Expect = 1e-10, Method: Composition-based stats.
Identities = 44/118 (37%), Positives = 62/118 (53%), Gaps = 10/118 (8%)
Query 1022 DIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSC 1081
DI K A IVNAAN +L HGGGVA A+ ++ +Q+ESD+Y++ NGP+ VG
Sbjct 19 DITKVEADA----IVNAANSYLSHGGGVALAIVRSGGYIIQEESDEYVRRNGPVPVGEVA 74
Query 1082 LLSGHNL-AKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDIL-----LAPLLSAGIFG 1133
+ + L A+ +H VGP D +L A + D L P +S GI+G
Sbjct 75 VTTAGKLKARYVIHAVGPRYGIEGDDKLESAIRRSLEKADELKLSSIALPAISTGIYG 132
>sp|Q96XY5|Y2383_SULTO Uncharacterized protein STK_23830 OS=Sulfurisphaera
tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140
/ 7) OX=273063 GN=STK_23830 PE=4 SV=1
Length=182
Score = 62.4 bits (150), Expect = 7e-09, Method: Composition-based stats.
Identities = 41/106 (39%), Positives = 61/106 (58%), Gaps = 8/106 (8%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN +L+HGGGVA A+ + +QKES +Y++ GP+ GG + S L AK +
Sbjct 18 IVNAANSYLEHGGGVARAIVEKGGYIIQKESREYVRKYGPVPTGGVAVTSAGKLKAKYVI 77
Query 1094 HVVGPNLNAGEDIQLLKAAYENF--NSQDILLA----PLLSAGIFG 1133
H VGP E + L+ A N ++++ L+ P +S GI+G
Sbjct 78 HAVGPRYGI-EGEEKLEEAIRNALRKAEELKLSSIALPAISTGIYG 122
>sp|P0C6F3|R1A_BEV Replicase polyprotein 1a OS=Berne virus OX=11156
GN=1a PE=1 SV=1
Length=4569
Score = 65.1 bits (157), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 51/182 (28%), Positives = 85/182 (47%), Gaps = 13/182 (7%)
Query 962 LEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQF----TGYLKLTDNVA 1017
L+ G+ E V V+ + +++ + E+ E + P E +F T + + D+
Sbjct 1641 LDIGSQCERVFVDYDVKKNEWTLSPEEGEDSDDNLDLPFEQYYEFKIGQTNVVLVQDDFK 1700
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ +K Q + +VN AN LKHGGG+A ++ +Q S++YI N + V
Sbjct 1701 -SVFEFLKSEQGVD--YVVNPANSQLKHGGGIAKVISCMCGPKLQAWSNNYITKNKTVPV 1757
Query 1078 GGSCLLSGHNLAKKC--LHVVGPNLNAGEDIQLLKAAYENF----NSQDILLAPLLSAGI 1131
+ G L KK +H VGP ++ G+ Q L A+ + Q +L +LS GI
Sbjct 1758 TKAIKSPGFQLGKKVNIIHAVGPRVSDGDVFQKLDQAWRSVFDLCEDQHTILTSMLSTGI 1817
Query 1132 FG 1133
FG
Sbjct 1818 FG 1819
>sp|A7MG20|YMDB_CROS8 O-acetyl-ADP-ribose deacetylase OS=Cronobacter
sakazakii (strain ATCC BAA-894) OX=290339 GN=ymdB PE=3
SV=1
Length=180
Score = 59.3 bits (142), Expect = 8e-08, Method: Composition-based stats.
Identities = 49/156 (31%), Positives = 71/156 (46%), Gaps = 21/156 (13%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKC- 1092
VIVNAAN L GGGV GA+++A A+ + G G + + +LA K
Sbjct 19 VIVNAANPSLMGGGGVDGAIHRAAGPALLAACRQVRQQQGECQPGHAVITEAGDLAAKAV 78
Query 1093 LHVVGPNLNAGED--IQLLKAAYEN------FNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP G+D QLL AY N N + + P +S GI+G + Q+
Sbjct 79 VHTVGPVWRGGQDNEPQLLADAYRNSLQLVAANGYNSVAFPAISTGIYGYPKAAAAQIAF 138
Query 1145 QTVR---------TQVYIAVNDKA---LYEQVVMDY 1168
+TV QVY D+ LY++++ Y
Sbjct 139 ETVSDYLTRHPQPKQVYFVCYDEENFLLYQRLLGQY 174
>sp|B5F961|YMDB_SALA4 O-acetyl-ADP-ribose deacetylase OS=Salmonella
agona (strain SL483) OX=454166 GN=ymdB PE=3 SV=1
Length=179
Score = 58.5 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 52/157 (33%), Positives = 72/157 (46%), Gaps = 21/157 (13%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN L GGGV GA+++A A+ + G G + + L AK +
Sbjct 20 IVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQQGECQTGHAVITPAGKLSAKAVI 79
Query 1094 HVVGPNLNAGE--DIQLLKAAYENFNSQDILLA----------PLLSAGIFGAKPLQSLQ 1141
H VGP GE + +LL+AAY N +LLA P +S G++G Q+ +
Sbjct 80 HTVGPVWRGGEYQEAELLEAAYRNC----LLLAEANHFRSIAFPAISTGVYGYPRAQAAE 135
Query 1142 VCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
V V+TV + AL EQV D R+ A
Sbjct 136 VAVRTVSD----FITRYALPEQVYFVCYDEETARLYA 168
>sp|P0C6F4|R1A_BRV1 Replicase polyprotein 1a OS=Breda virus 1
OX=360393 GN=1a PE=3 SV=1
Length=4445
Score = 62.4 bits (150), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 51/184 (28%), Positives = 85/184 (46%), Gaps = 17/184 (9%)
Query 962 LEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGY------LKLTDN 1015
L+ G+S E V V+ + ++ D +T ++ + E P NQ+ + + L +
Sbjct 1595 LDVGSSLEQVYVDYDVSKNVWDLSTH---LQDDSSDDLELPFNQYYEFKVGRASVVLVQD 1651
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPL 1075
D +K Q + +VN AN LKHGGG+A ++ + S++YIK L
Sbjct 1652 DFKSVYDFLKSEQGVD--YVVNPANNQLKHGGGIAKVISCMCGPKLTSWSNNYIKQYKKL 1709
Query 1076 TVGGSCLLSGHNLAK--KCLHVVGPNLNAGEDIQLLKAA----YENFNSQDILLAPLLSA 1129
V + G L K + +HVVGP + + L+A+ ++N +L +LS
Sbjct 1710 GVTCAIRSPGFQLGKGVQIIHVVGPKSADSDVVNKLEASWRSVFQNVKPDTTVLTSMLST 1769
Query 1130 GIFG 1133
GIFG
Sbjct 1770 GIFG 1773
Score = 38.1 bits (87), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 37/148 (25%), Positives = 69/148 (47%), Gaps = 16/148 (11%)
Query 3024 VVAGGIIAILVTCAAYYFMKFRRV-------FGEYNHVVAANALLFLMSFTILCLVPAYS 3076
+++ + +LV F+ R+ F + +VV LLF+ + +L +V
Sbjct 2937 IISPYVFVVLVAIFTIVFLFLLRMYIVMYSYFKVFTYVVFK--LLFVNTVMVLFVVCLPP 2994
Query 3077 FLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNN 3136
+PGV V L+L + V FL +L ++F I+P++ ++V + W +
Sbjct 2995 LVPGVVFVLALWL----CDSVVFLLYLAVLSLF--ILPWFYVMLFVLIVGGFVFWWMMKS 3048
Query 3137 YLRKRVMFNGVTFS-TFEEAALCTFLLN 3163
+ +G+TF+ TFE+ + C F LN
Sbjct 3049 SDVVHLTPDGLTFNGTFEQVSKCVFPLN 3076
>sp|A8AI35|YMDB_CITK8 O-acetyl-ADP-ribose deacetylase OS=Citrobacter
koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
OX=290338 GN=ymdB PE=3 SV=1
Length=177
Score = 58.2 bits (139), Expect = 2e-07, Method: Composition-based stats.
Identities = 50/155 (32%), Positives = 75/155 (48%), Gaps = 25/155 (16%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL-LSGHNLAKKC 1092
VIVNAAN L GGGV GA+++A + + + G G + + L+G+ AK
Sbjct 19 VIVNAANASLLGGGGVDGAIHRAAGPTLLEACKKVRQQQGECPAGHAVITLAGNLPAKAV 78
Query 1093 LHVVGPNLNAGE--DIQLLKAAYENFNSQDILLA--------PLLSAGIFGAKPLQSLQV 1142
+H VGP G+ + QLL+ AY FNS ++LA P +S G +G + ++
Sbjct 79 IHTVGPVWRGGDHNESQLLEDAY--FNSLQLVLANGYRSVAFPAISTGAYGYPRPAAAEI 136
Query 1143 CVQTVR---------TQVYIAVNDKA---LYEQVV 1165
V TV QVY D+ LYE+++
Sbjct 137 AVNTVADFLARHALPEQVYFVCYDEETARLYERLL 171
>sp|P67341|YMDB_SALTY O-acetyl-ADP-ribose deacetylase OS=Salmonella
typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287
GN=ymdB PE=3 SV=1
Length=179
Score = 56.6 bits (135), Expect = 8e-07, Method: Composition-based stats.
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 21/157 (13%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN L GGGV GA+++A A+ + G G + + L AK +
Sbjct 20 IVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQQGECQTGHAVITPAGKLSAKAVI 79
Query 1094 HVVGPNLNAGE--DIQLLKAAYENFNSQDILLA----------PLLSAGIFGAKPLQSLQ 1141
H VGP GE + +LL+ AY N +LLA P +S G++G Q+ +
Sbjct 80 HTVGPVWRGGEHQEAELLEEAYRNC----LLLAEANHFRSIAFPAISTGVYGYPRAQAAE 135
Query 1142 VCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
V V+TV + AL EQV D R+ A
Sbjct 136 VAVRTVSD----FITRYALPEQVYFVCYDEETARLYA 168
>sp|P67342|YMDB_SALTI O-acetyl-ADP-ribose deacetylase OS=Salmonella
typhi OX=90370 GN=ymdB PE=3 SV=1
Length=179
Score = 56.6 bits (135), Expect = 8e-07, Method: Composition-based stats.
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 21/157 (13%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN L GGGV GA+++A A+ + G G + + L AK +
Sbjct 20 IVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQQGECQTGHAVITPAGKLSAKAVI 79
Query 1094 HVVGPNLNAGE--DIQLLKAAYENFNSQDILLA----------PLLSAGIFGAKPLQSLQ 1141
H VGP GE + +LL+ AY N +LLA P +S G++G Q+ +
Sbjct 80 HTVGPVWRGGEHQEAELLEEAYRNC----LLLAEANHFRSIAFPAISTGVYGYPRAQAAE 135
Query 1142 VCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
V V+TV + AL EQV D R+ A
Sbjct 136 VAVRTVSD----FITRYALPEQVYFVCYDEETARLYA 168
>sp|B4T2X8|YMDB_SALNS O-acetyl-ADP-ribose deacetylase OS=Salmonella
newport (strain SL254) OX=423368 GN=ymdB PE=3 SV=1
Length=179
Score = 55.8 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 50/157 (32%), Positives = 71/157 (45%), Gaps = 21/157 (13%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN L GGGV GA+++A A+ + G G + + L AK +
Sbjct 20 IVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQQGECQTGHAVITPAGKLSAKAVI 79
Query 1094 HVVGPNLNAGE--DIQLLKAAYENFNSQDILLA----------PLLSAGIFGAKPLQSLQ 1141
H VGP GE + +LL+ AY N +LLA P +S G++G Q+ +
Sbjct 80 HTVGPVWRGGEHQEAELLEEAYRNC----LLLAEANHFRSIAFPAISTGVYGYPRAQAAE 135
Query 1142 VCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
+ V+TV + AL EQV D R+ A
Sbjct 136 IAVRTVSD----FITRYALPEQVYFVCYDEETARLYA 168
>sp|B6SFA4|MAA3_ARATH Probable helicase MAGATAMA 3 OS=Arabidopsis
thaliana OX=3702 GN=MAA3 PE=2 SV=1
Length=818
Score = 58.5 bits (140), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 68/251 (27%), Positives = 99/251 (39%), Gaps = 47/251 (19%)
Query 5670 DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC-R 5728
D+V+ DE + A +++ R K +GDP QLPA T+++ + Y S+ R
Sbjct 485 DVVIIDEAAQAVE-PATLIPLATRCKQVFLVGDPKQLPA--TVISTVAQDSGYGTSMFER 541
Query 5729 LMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ--------------CFK 5774
L K P L T R EI S Y+ L+ D AQ CF
Sbjct 542 LQKAGYPVKMLKTQYRMHPEIRSFPSKQFYEGALEDGSDIEAQTTRDWHKYRCFGPFCFF 601
Query 5775 MFYKGVITHD---VSSAINRPQIGVV----REFLTRNPAWRKA---VFISPYNSQ----- 5819
++G + S +N ++ V +T P + + ISPYN Q
Sbjct 602 DIHEGKESQHPGATGSRVNLDEVEFVLLIYHRLVTMYPELKSSSQLAIISPYNYQVKTFK 661
Query 5820 -------NAVASKILGLPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAIT 5867
A K++ + TVD QG E D IF+ + + N R NV IT
Sbjct 662 DRFKEMFGTEAEKVVDI--NTVDGFQGREKDVAIFSCVRANENGQIGFLSNSRRMNVGIT 719
Query 5868 RAKIGILCIMS 5878
RAK +L + S
Sbjct 720 RAKSSVLVVGS 730
>sp|P0A8D6|YMDB_ECOLI O-acetyl-ADP-ribose deacetylase OS=Escherichia
coli (strain K12) OX=83333 GN=ymdB PE=1 SV=1
Length=177
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 48/140 (34%), Positives = 68/140 (49%), Gaps = 13/140 (9%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL-LSGHNLAKKC 1092
VIVNAAN L GGGV GA+++A A+ + G G + + L+G AK
Sbjct 19 VIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAV 78
Query 1093 LHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP GE + QLL+ AY N NS + P +S G++G + ++ V
Sbjct 79 VHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAV 138
Query 1145 QTVRTQVYIAVNDKALYEQV 1164
+TV + AL EQV
Sbjct 139 KTVSE----FITRHALPEQV 154
>sp|P0A8D7|YMDB_ECOL6 O-acetyl-ADP-ribose deacetylase OS=Escherichia
coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) OX=199310
GN=ymdB PE=3 SV=1
Length=177
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 48/140 (34%), Positives = 68/140 (49%), Gaps = 13/140 (9%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL-LSGHNLAKKC 1092
VIVNAAN L GGGV GA+++A A+ + G G + + L+G AK
Sbjct 19 VIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAV 78
Query 1093 LHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP GE + QLL+ AY N NS + P +S G++G + ++ V
Sbjct 79 VHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAV 138
Query 1145 QTVRTQVYIAVNDKALYEQV 1164
+TV + AL EQV
Sbjct 139 KTVSE----FITRHALPEQV 154
>sp|P0A8D8|YMDB_ECO57 O-acetyl-ADP-ribose deacetylase OS=Escherichia
coli O157:H7 OX=83334 GN=ymdB PE=3 SV=1
Length=177
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 48/140 (34%), Positives = 68/140 (49%), Gaps = 13/140 (9%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL-LSGHNLAKKC 1092
VIVNAAN L GGGV GA+++A A+ + G G + + L+G AK
Sbjct 19 VIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAV 78
Query 1093 LHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP GE + QLL+ AY N NS + P +S G++G + ++ V
Sbjct 79 VHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAV 138
Query 1145 QTVRTQVYIAVNDKALYEQV 1164
+TV + AL EQV
Sbjct 139 KTVSE----FITRHALPEQV 154
>sp|B5RBF3|YMDB_SALG2 O-acetyl-ADP-ribose deacetylase OS=Salmonella
gallinarum (strain 287/91 / NCTC 13346) OX=550538 GN=ymdB
PE=3 SV=1
Length=179
Score = 54.3 bits (129), Expect = 4e-06, Method: Composition-based stats.
Identities = 50/157 (32%), Positives = 71/157 (45%), Gaps = 21/157 (13%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN L GGGV GA+++A A+ + G G + + L AK +
Sbjct 20 IVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQQGECQTGHAVITPAGKLSAKAVI 79
Query 1094 HVVGPNLNAGE--DIQLLKAAYENFNSQDILLA----------PLLSAGIFGAKPLQSLQ 1141
H VGP GE + +LL+ AY + +LLA P +S G++G Q+ +
Sbjct 80 HTVGPVWRGGEHQEAELLEEAYRSC----LLLAEANHFRSIAFPAISTGVYGYPRAQAAE 135
Query 1142 VCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
V V+TV + AL EQV D R+ A
Sbjct 136 VAVRTVSD----FITRYALPEQVYFVCYDEETARLYA 168
>sp|C9Y0V8|YMDB_CROTZ O-acetyl-ADP-ribose deacetylase OS=Cronobacter
turicensis (strain DSM 18703 / CCUG 55852 / LMG 23827
/ z3032) OX=693216 GN=ymdB PE=3 SV=1
Length=176
Score = 54.3 bits (129), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 70/156 (45%), Gaps = 21/156 (13%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKC- 1092
VIVNAAN L GGGV GA+++A ++ + G G + + +LA K
Sbjct 19 VIVNAANPSLMGGGGVDGAIHRAAGPSLLAACKVVRQQQGECQPGHAVITEAGDLAAKAV 78
Query 1093 LHVVGPNLNAGED--IQLLKAAYEN------FNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP G D QLL AY N N + + P +S GI+G + Q+
Sbjct 79 IHTVGPIWRGGHDNEPQLLADAYRNSLELVTANGYNSVAFPAISTGIYGYPKAAAAQIAF 138
Query 1145 QTVR---------TQVYIAVNDKA---LYEQVVMDY 1168
+TV QVY D+ LY++++ Y
Sbjct 139 ETVSDYLTRRPQPKQVYFVCYDEENFLLYQRLLGQY 174
>sp|D3RKJ0|YMDB_KLEVT O-acetyl-ADP-ribose deacetylase OS=Klebsiella
variicola (strain At-22) OX=640131 GN=ymdB PE=3 SV=1
Length=175
Score = 53.9 bits (128), Expect = 5e-06, Method: Composition-based stats.
Identities = 38/123 (31%), Positives = 63/123 (51%), Gaps = 9/123 (7%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL-LSGHNLAKKC 1092
VIVNAAN L GGGV GA+++A A+ ++ G G + + ++G A
Sbjct 19 VIVNAANPSLLGGGGVDGAIHRAAGPALLAACKQVLQQQGECPPGHAVITIAGDLPASAV 78
Query 1093 LHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP + G+ + Q L AY+N N+ + P +S G++G ++ ++ V
Sbjct 79 IHTVGPVWHGGDRMEAQTLADAYKNSLQLAAANNYRSIAFPAISTGVYGYPKEEAAEIAV 138
Query 1145 QTV 1147
+TV
Sbjct 139 RTV 141
>sp|B5XXK9|YMDB_KLEP3 O-acetyl-ADP-ribose deacetylase OS=Klebsiella
pneumoniae (strain 342) OX=507522 GN=ymdB PE=3 SV=1
Length=175
Score = 53.9 bits (128), Expect = 5e-06, Method: Composition-based stats.
Identities = 38/123 (31%), Positives = 63/123 (51%), Gaps = 9/123 (7%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL-LSGHNLAKKC 1092
VIVNAAN L GGGV GA+++A A+ ++ G G + + ++G A
Sbjct 19 VIVNAANPSLLGGGGVDGAIHRAAGPALLAACKQVLQQQGECPPGHAVITIAGDLPASAV 78
Query 1093 LHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP + G+ + Q L AY+N N+ + P +S G++G ++ ++ V
Sbjct 79 IHTVGPVWHGGDRMEAQTLADAYKNSLQLAAANNYRSIAFPAISTGVYGYPKEEAAEIAV 138
Query 1145 QTV 1147
+TV
Sbjct 139 RTV 141
>sp|Q8CAS9|PARP9_MOUSE Protein mono-ADP-ribosyltransferase PARP9
OS=Mus musculus OX=10090 GN=Parp9 PE=1 SV=2
Length=866
Score = 55.8 bits (133), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 44/139 (32%), Positives = 65/139 (47%), Gaps = 16/139 (12%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA-KKCL 1093
+VNAAN +L HG G+AG+L K +Q+ES I G ++VGG + L +
Sbjct 137 VVNAANENLLHGSGLAGSLVKTGGFEIQEESKRIIANVGKISVGGIAITGAGRLPCHLII 196
Query 1094 HVVGPNL---NAGEDIQLLKAAYENF----NSQDILLA----PLLSAGIFGAKPLQSLQV 1142
H VGP N+ I+LLK A N D+ + P LS+GIF L +
Sbjct 197 HAVGPRWTVTNSQTAIELLKFAIRNILDYVTKYDLRIKTVAIPALSSGIFQF----PLDL 252
Query 1143 CVQTVRTQVYIAVNDKALY 1161
C + + + DK ++
Sbjct 253 CTSIILETIRLYFQDKQMF 271
>sp|Q0T5Z6|YMDB_SHIF8 O-acetyl-ADP-ribose deacetylase OS=Shigella
flexneri serotype 5b (strain 8401) OX=373384 GN=ymdB PE=3
SV=1
Length=177
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 47/140 (34%), Positives = 67/140 (48%), Gaps = 13/140 (9%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL-LSGHNLAKKC 1092
VIVNAAN L GGGV GA+++A A+ + G G + + L+G AK
Sbjct 19 VIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAV 78
Query 1093 LHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP GE + QLL+ AY N NS + P +S G++ + ++ V
Sbjct 79 VHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAISTGVYSYPRAAAAEIAV 138
Query 1145 QTVRTQVYIAVNDKALYEQV 1164
+TV + AL EQV
Sbjct 139 KTVSE----FITRHALPEQV 154
>sp|A4W960|YMDB_ENT38 O-acetyl-ADP-ribose deacetylase OS=Enterobacter
sp. (strain 638) OX=399742 GN=ymdB PE=3 SV=1
Length=180
Score = 52.4 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 39/123 (32%), Positives = 59/123 (48%), Gaps = 9/123 (7%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL-LSGHNLAKKC 1092
VIVNAAN L GGGV GA+++A + + + G G + + ++G AK
Sbjct 19 VIVNAANPSLMGGGGVDGAIHRAAGPQLLEACKTVRQQQGECAPGHAVITIAGDLPAKAV 78
Query 1093 LHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP GE + + L+ AY N N L P +S G++G + ++ V
Sbjct 79 IHAVGPVWQGGENHEARTLQDAYLNCLRLAAANGYKTLAFPAISTGVYGYPKAAAAEIAV 138
Query 1145 QTV 1147
TV
Sbjct 139 DTV 141
>sp|Q460N5|PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14
OS=Homo sapiens OX=9606 GN=PARP14 PE=1 SV=3
Length=1801
Score = 55.8 bits (133), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 40/125 (32%), Positives = 60/125 (48%), Gaps = 16/125 (13%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA-KKC 1092
V+VNA+N LKH GG+A AL+KA +Q + D +K G L G + + L
Sbjct 818 VVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKAGKLPYHHV 877
Query 1093 LHVVGPNLNAGE----------DIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQV 1142
+H VGP + E +QL E + + I + P +S+G+FG L
Sbjct 878 IHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAI-PAISSGVFGF----PLGR 932
Query 1143 CVQTV 1147
CV+T+
Sbjct 933 CVETI 937
>sp|B7LT90|YMDB_ESCF3 O-acetyl-ADP-ribose deacetylase OS=Escherichia
fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766
/ IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128
/ CDC 0568-73) OX=585054 GN=ymdB PE=3 SV=2
Length=177
Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 40/123 (33%), Positives = 59/123 (48%), Gaps = 9/123 (7%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKC 1092
VIVNAAN L GGGV GA+++A + + + G G + + NL A+
Sbjct 19 VIVNAANSSLMGGGGVDGAIHRAAGPELLEACQKVRRQQGECPTGHAVITIAGNLPARAV 78
Query 1093 LHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP GE + QLL AY N N + P +S G++G + ++ V
Sbjct 79 IHTVGPVWRDGEHNEDQLLHDAYLNSLKLAQANGYKSIAFPAISTGVYGFPRAAAAEIAV 138
Query 1145 QTV 1147
+TV
Sbjct 139 KTV 141
>sp|D2TT52|YMDB_CITRI O-acetyl-ADP-ribose deacetylase OS=Citrobacter
rodentium (strain ICC168) OX=637910 GN=ymdB PE=3 SV=2
Length=177
Score = 52.0 bits (123), Expect = 3e-05, Method: Composition-based stats.
Identities = 40/124 (32%), Positives = 60/124 (48%), Gaps = 13/124 (10%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN L GGGV GA+++A + + + G G + + + L AK +
Sbjct 20 IVNAANPSLMGGGGVDGAIHRAAGPELLEACMTVRRQQGECPPGHAVITAAGRLPAKAVI 79
Query 1094 HVVGPNLNAGE--DIQLLKAAYENFNSQDILLA--------PLLSAGIFGAKPLQSLQVC 1143
H VGP GE + QLL AY NS ++ LA P +S G++G + ++
Sbjct 80 HTVGPIWRGGEHNEAQLLHDAY--LNSLNLALANGYQSIAFPAISTGVYGYPRAAAAEIA 137
Query 1144 VQTV 1147
V T+
Sbjct 138 VNTI 141
>sp|P36327|POLN_EEVV3 Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain 3880) OX=36382 PE=3 SV=3
Length=2485
Score = 55.5 bits (132), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 52/145 (36%), Positives = 65/145 (45%), Gaps = 26/145 (18%)
Query 1029 SANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL 1088
+A VI+NAAN + GGGV GAL K ES D P+ VG + L+ G
Sbjct 1342 TATEGVIINAANSKGQPGGGVCGALYKKF-----PESFDL----QPIEVGKARLVKG--A 1390
Query 1089 AKKCLHVVGPNLNAGEDIQ---LLKAAYE------NFNSQDILLAPLLSAGIFGA----- 1134
AK +H VGPN N +I+ L AYE N N+ + PLLS GIF
Sbjct 1391 AKHIIHAVGPNFNKVSEIEGDKQLAEAYESIAKIVNDNNYKSVAIPLLSTGIFSGNKDRL 1450
Query 1135 -KPLQSLQVCVQTVRTQVYIAVNDK 1158
+ L L + T V I DK
Sbjct 1451 TQSLNHLLTALDTTDADVAIYCRDK 1475
>sp|Q8RHQ2|Y1951_FUSNN Uncharacterized protein FN1951 OS=Fusobacterium
nucleatum subsp. nucleatum (strain ATCC 25586 / DSM
15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG
13131 / VPI 4355) OX=190304 GN=FN1951 PE=4 SV=1
Length=175
Score = 52.0 bits (123), Expect = 3e-05, Method: Composition-based stats.
Identities = 38/107 (36%), Positives = 55/107 (51%), Gaps = 13/107 (12%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKK-CL 1093
IVNAAN L+ GGGV GA+ KA + +E + G G + + G+NL K +
Sbjct 22 IVNAANSSLEMGGGVCGAIFKAAGSELAQECKEI----GGCNTGEAVITKGYNLPNKYII 77
Query 1094 HVVGPNLNAGEDIQ---LLKAAYENF---NSQDI--LLAPLLSAGIF 1132
H VGP + GE+ + L A YE+ N + I + P +S GI+
Sbjct 78 HTVGPRYSTGENREAERLASAYYESLKLANEKGIRRIAFPSISTGIY 124
>sp|Q32E73|YMDB_SHIDS O-acetyl-ADP-ribose deacetylase OS=Shigella
dysenteriae serotype 1 (strain Sd197) OX=300267 GN=ymdB
PE=3 SV=1
Length=177
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 46/140 (33%), Positives = 66/140 (47%), Gaps = 13/140 (9%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL-LSGHNLAKKC 1092
VIVN N L GGGV GA+++A A+ + G G + + L+G AK
Sbjct 19 VIVNVTNPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAV 78
Query 1093 LHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP GE + QLL+ AY N NS + P +S G++G + ++ V
Sbjct 79 VHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAV 138
Query 1145 QTVRTQVYIAVNDKALYEQV 1164
+TV + AL EQV
Sbjct 139 KTVSE----FITRHALPEQV 154
>sp|P27282|POLN_EEVVT Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain Trinidad donkey) OX=11038 PE=1 SV=3
Length=2493
Score = 54.7 bits (130), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 51/145 (35%), Positives = 65/145 (45%), Gaps = 26/145 (18%)
Query 1029 SANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL 1088
+A VI+NAAN + GGGV GAL K ES D P+ VG + L+ G
Sbjct 1342 TATEGVIINAANSKGQPGGGVCGALYKKF-----PESFDL----QPIEVGKARLVKG--A 1390
Query 1089 AKKCLHVVGPNLNAGEDIQ---LLKAAYE------NFNSQDILLAPLLSAGIFGA----- 1134
AK +H VGPN N +++ L AYE N N+ + PLLS GIF
Sbjct 1391 AKHIIHAVGPNFNKVSEVEGDKQLAEAYESIAKIVNDNNYKSVAIPLLSTGIFSGNKDRL 1450
Query 1135 -KPLQSLQVCVQTVRTQVYIAVNDK 1158
+ L L + T V I DK
Sbjct 1451 TQSLNHLLTALDTTDADVAIYCRDK 1475
>sp|P36328|POLN_EEVVP Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain P676) OX=36385 PE=1 SV=2
Length=2493
Score = 54.7 bits (130), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 51/145 (35%), Positives = 65/145 (45%), Gaps = 26/145 (18%)
Query 1029 SANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL 1088
+A VI+NAAN + GGGV GAL K ES D P+ VG + L+ G
Sbjct 1342 TATEGVIINAANSKGQPGGGVCGALYKKF-----PESFDL----QPIEVGKARLVKG--A 1390
Query 1089 AKKCLHVVGPNLNAGEDIQ---LLKAAYE------NFNSQDILLAPLLSAGIFGA----- 1134
AK +H VGPN N +++ L AYE N N+ + PLLS GIF
Sbjct 1391 AKHIIHAVGPNFNKVSEVEGDKQLAEAYESIAKIVNDNNYKSVAIPLLSTGIFSGNKDRL 1450
Query 1135 -KPLQSLQVCVQTVRTQVYIAVNDK 1158
+ L L + T V I DK
Sbjct 1451 TQSLNHLLTALDTTDADVAIYCRDK 1475
>sp|D5CE05|YMDB_ENTCC O-acetyl-ADP-ribose deacetylase OS=Enterobacter
cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054
/ NBRC 13535 / NCTC 10005 / WDCM 00083 / NCDC 279-56) OX=716541
GN=ymdB PE=3 SV=1
Length=180
Score = 50.8 bits (120), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 38/123 (31%), Positives = 59/123 (48%), Gaps = 9/123 (7%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL-LSGHNLAKKC 1092
VIVNAAN L GGGV GA+++A + + + G G + + L+G AK
Sbjct 19 VIVNAANPSLMGGGGVDGAIHRAAGPQLLEACKTVRQQQGECPPGHAVITLAGDLPAKAV 78
Query 1093 LHVVGPNLNAGE--DIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP + G+ + +L+ AY N N + P +S G++G + + V
Sbjct 79 IHAVGPIWHGGDRHEASILEEAYRNCLRLAADNGYKTMAFPAISTGVYGYPKAAAATIAV 138
Query 1145 QTV 1147
TV
Sbjct 139 DTV 141
>sp|Q8IXQ6|PARP9_HUMAN Protein mono-ADP-ribosyltransferase PARP9
OS=Homo sapiens OX=9606 GN=PARP9 PE=1 SV=2
Length=854
Score = 52.0 bits (123), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 47/160 (29%), Positives = 76/160 (48%), Gaps = 19/160 (12%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA-KKCL 1093
+VNAAN L HGGG+A AL KA +Q+ES ++ G ++ G + L K+ +
Sbjct 135 VVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQII 194
Query 1094 HVVGPNL----NAGEDIQLLKA--------AYENFNSQDILLAPLLSAGIFGAKPLQSLQ 1141
H VGP G +L +A Y+N + + + + P LS+GIF L
Sbjct 195 HAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAI-PALSSGIFQF----PLN 249
Query 1142 VCVQTVRTQVYIAVNDKALYEQVVMDYL-DNLKPRVEAPK 1180
+C +T+ + +++ K + + +L N P V A K
Sbjct 250 LCTKTIVETIRVSLQGKPMMSNLKEIHLVSNEDPTVAAFK 289
>sp|Q87JZ5|Y4103_VIBPA Macro domain-containing protein VPA0103
OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
OX=223926 GN=VPA0103 PE=4 SV=1
Length=170
Score = 48.5 bits (114), Expect = 4e-04, Method: Composition-based stats.
Identities = 42/141 (30%), Positives = 71/141 (50%), Gaps = 17/141 (12%)
Query 1029 SANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKES---DDYIKLNGPLTVGGSCLLSG 1085
+A+ IVNAAN + GGGV GA+++A A+ DD + P G + +
Sbjct 13 TAHVDAIVNAANPRMLGGGGVDGAIHRAAGPALINACYAVDDVDGIRCPF--GDARITEA 70
Query 1086 HNL-AKKCLHVVGPNLNAGEDIQ-LLKAAYENFNSQDILLA--------PLLSAGIFGAK 1135
NL A+ +H VGP + D + +L++AY+ S D+ LA P +S G++G
Sbjct 71 GNLNARYVIHAVGPIYDKFADPKTVLESAYQ--RSLDLALANHCQSVALPAISCGVYGYP 128
Query 1136 PLQSLQVCVQTVRTQVYIAVN 1156
P ++ +V + + Y A++
Sbjct 129 PQEAAEVAMAVCQRPEYAALD 149
>sp|Q8V294|POLN_EEVVC Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain CPA201) OX=376610 PE=3 SV=3
Length=2497
Score = 51.6 bits (122), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 49/145 (34%), Positives = 65/145 (45%), Gaps = 26/145 (18%)
Query 1029 SANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL 1088
+A VIVNAAN + G GV GAL + ES D P+ VG + L+ G+
Sbjct 1342 TATEGVIVNAANSKGQPGSGVCGALYRK-----YPESFDL----QPIEVGKARLVKGN-- 1390
Query 1089 AKKCLHVVGPNLNAGEDIQ---LLKAAYE------NFNSQDILLAPLLSAGIFGA----- 1134
+K +H VGPN N +++ L AYE N N+ + PLLS GIF
Sbjct 1391 SKHLIHAVGPNFNKVSEVEGDKQLAEAYESIARIINDNNYRSVAIPLLSTGIFAGNKDRL 1450
Query 1135 -KPLQSLQVCVQTVRTQVYIAVNDK 1158
+ L L + T V I DK
Sbjct 1451 MQSLNHLLTALDTTDADVAIYCRDK 1475
>sp|Q8RB30|Y995_CALS4 Macro domain-containing protein TTE0995
OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain
DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=TTE0995
PE=4 SV=1
Length=175
Score = 47.8 bits (112), Expect = 7e-04, Method: Composition-based stats.
Identities = 42/124 (34%), Positives = 61/124 (49%), Gaps = 13/124 (10%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN L GGGV GA++KA A+ +E + G G + + NL AK +
Sbjct 20 IVNAANSSLIGGGGVDGAIHKAGGPAIAEELKVIREKQGGCPTGHAVITGAGNLKAKYVI 79
Query 1094 HVVGP----------NLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVC 1143
H VGP NL A I+ LK A E +N + I P +S G +G ++ ++
Sbjct 80 HAVGPIWKGGNHNEDNLLASAYIESLKLADE-YNVKTIAF-PSISTGAYGFPVERAARIA 137
Query 1144 VQTV 1147
++ V
Sbjct 138 LRVV 141
>sp|Q2EMV9|PAR14_MOUSE Protein mono-ADP-ribosyltransferase PARP14
OS=Mus musculus OX=10090 GN=Parp14 PE=1 SV=3
Length=1817
Score = 50.4 bits (119), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 44/137 (32%), Positives = 65/137 (47%), Gaps = 17/137 (12%)
Query 1023 IVKEAQSANPM-VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSC 1081
+++E S P+ V+VNAAN +LKH G+A AL+KA +Q E D +K G + G +
Sbjct 817 VLEEDLSRFPVDVVVNAANENLKHISGLAQALSKAAGPELQTECDQIVKEGGVVLPGNAV 876
Query 1082 LLSGHNLA-KKCLHVVGPNLNAG---EDIQLLKAAY-------ENFNSQDILLAPLLSAG 1130
+ L +H VGP E + LLK E + I + P +SAG
Sbjct 877 ISKAGKLPCHHVIHAVGPRWKGDKVLECVSLLKKVVRQSLSLAEEHRCRSIAM-PAVSAG 935
Query 1131 IFGAKPLQSLQVCVQTV 1147
IF L++CV +
Sbjct 936 IFDF----PLELCVANI 948
>sp|Q8KAE4|Y2219_CHLTE Macro domain-containing protein CT2219
OS=Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC
103806 / TLS) OX=194439 GN=CT2219 PE=4 SV=1
Length=172
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 46/146 (32%), Positives = 69/146 (47%), Gaps = 15/146 (10%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ DNV I + + S IVNAAN L GGGV GA+++A + + + L
Sbjct 1 MPDNVLIHAIK--ADITSLTVDAIVNAANTSLLGGGGVDGAIHRAAGPKLLEACRE---L 55
Query 1072 NGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENFNSQDI------L 1122
G LT G + + G+ L A +H VGP + G + +LL + Y N I +
Sbjct 56 GGCLT-GEAKITKGYRLPATFVIHTVGPVWHGGNHGEAELLASCYRNSLKLAIEHHCRTI 114
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTVR 1148
P +S GI+G Q+ + + TVR
Sbjct 115 AFPSISTGIYGYPVEQAAAIAITTVR 140
>sp|P38859|DNA2_YEAST DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Saccharomyces cerevisiae (strain ATCC 204508
/ S288c) OX=559292 GN=DNA2 PE=1 SV=1
Length=1522
Score = 49.7 bits (117), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 58/211 (27%), Positives = 90/211 (43%), Gaps = 28/211 (13%)
Query 5576 QKYSTLQGPPGTGKSHF--AIGLALYYPSARIVYTACSHAAVDALCEK-----------A 5622
+ Y+ + G PGTGK+ I L R++ T+ +H+AVD + K
Sbjct 1067 EDYALILGMPGTGKTTVIAEIIKILVSEGKRVLLTSYTHSAVDNILIKLRNTNISIMRLG 1126
Query 5623 LKYLPIDKCSRIIPARARVECFDKF--KVNSTLEQYVFCT-VN----ALPETTADIVVFD 5675
+K+ + +P A V+ ++ + K+NST C +N L E D V+ D
Sbjct 1127 MKHKVHPDTQKYVPNYASVKSYNDYLSKINSTSVVATTCLGINDILFTLNEKDFDYVILD 1186
Query 5676 EISMATNYDLSVVNARLR-AKHYVYIGDPAQLP--APRTLLTKGTLEPEYFNSVCRLMKT 5732
E A+ + V LR ++ +GD QLP G LE F + C
Sbjct 1187 E---ASQISMPVALGPLRYGNRFIMVGDHYQLPPLVKNDAARLGGLEESLFKTFCEKHPE 1243
Query 5733 IGPDMFLGTCRRCPAEIVDTVSALVYDNKLK 5763
++ L R C +IV + L+YDNKLK
Sbjct 1244 SVAELTL-QYRMC-GDIVTLSNFLIYDNKLK 1272
>sp|Q92355|SEN1_SCHPO Helicase sen1 OS=Schizosaccharomyces pombe
(strain 972 / ATCC 24843) OX=284812 GN=sen1 PE=1 SV=1
Length=1687
Score = 49.3 bits (116), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 67/244 (27%), Positives = 103/244 (42%), Gaps = 43/244 (18%)
Query 5672 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV-CRLM 5730
V+ DE + A D +++ R AK + +GDP QLP T+L+K Y S+ R+
Sbjct 1375 VIIDEAAQAVELD-TIIPLRYGAKKCILVGDPNQLPP--TVLSKKAASLNYSQSLFVRIQ 1431
Query 5731 KTIGPDM-FLGTCRRCPAEIVDTVSALVYDNKLKA------------HKDKSAQCFKMF- 5776
K M L R +I S YD++L+ H + +++F
Sbjct 1432 KNFSNQMCLLSIQYRMHPDISHFPSKKFYDSRLEDGDNMAEKTQQVWHVNPKFTQYRLFD 1491
Query 5777 YKGV-ITHDVSSAINRPQ----IGVVREFLTRNP----AWRKAVFISPYNSQ-----NAV 5822
+G T + S N + + +V E L + P R V I+PY SQ A
Sbjct 1492 VRGKERTSNTMSTYNLEEVEYLVNMVDELLNKFPDVNFTGRIGV-ITPYRSQLHELRRAF 1550
Query 5823 ASK-----ILGLPTQTVDSSQGSEYDYVIFT-QTTETAHSC----NVNRFNVAITRAKIG 5872
K + + QTVD QG E D + F+ + + H + R NVA+TRA+
Sbjct 1551 KVKYGKSFMSTIDIQTVDGFQGQEKDIIFFSCVKSYSKHGIGFLRDFRRLNVALTRARSS 1610
Query 5873 ILCI 5876
+L I
Sbjct 1611 LLII 1614
>sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 OS=Arabidopsis
thaliana OX=3702 GN=SDE3 PE=1 SV=1
Length=1002
Score = 49.3 bits (116), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 99/388 (26%), Positives = 144/388 (37%), Gaps = 100/388 (26%)
Query 5581 LQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAAVDALCEKAL----------KYL 5626
+ GPPGTGK+ + L +AR++ A S++A D + EK L +
Sbjct 419 IHGPPGTGKTMTLVEAIVQLYTTQRNARVLVCAPSNSAADHILEKLLCLEGVRIKDNEIF 478
Query 5627 PIDKCSR----IIPARARVECFDK--FK------------VNSTLEQYVFCTVNALPETT 5668
++ +R I P R FD+ FK V ST +
Sbjct 479 RLNAATRSYEEIKPEIIRFCFFDELIFKCPPLKALTRYKLVVSTYMSASLLNAEGVNRGH 538
Query 5669 ADIVVFDEISMATNYD--LSVVNARLRAKHYVYIGDPAQL-------PAPRTLLTKGTLE 5719
++ DE A+ + ++V N L V GDP QL A L K LE
Sbjct 539 FTHILLDEAGQASEPENMIAVSNLCLTETVVVLAGDPRQLGPVIYSRDAESLGLGKSYLE 598
Query 5720 P----EYF-----NSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSA 5770
+Y+ N V +L+K RC EI+D S L YD +L A K+ +
Sbjct 599 RLFECDYYCEGDENYVTKLVKNY----------RCHPEILDLPSKLFYDGELVASKEDTD 648
Query 5771 QC-----------FKMFYKGVITHDVS-----SAINRPQIGVVREFLTRNPA-----WRK 5809
F M + G+ D S NR +I V E + R A
Sbjct 649 SVLASLNFLPNKEFPMVFYGIQGCDEREGNNPSWFNRIEISKVIETIKRLTANDCVQEED 708
Query 5810 AVFISPYNSQNAVASKILG------LPTQTVDSSQGSEYDYVIFTQTTET-AHS------ 5856
I+PY Q ++L + +V+ QG E +I + T H+
Sbjct 709 IGVITPYRQQVMKIKEVLDRLDMTEVKVGSVEQFQGQEKQVIIISTVRSTIKHNEFDRAY 768
Query 5857 -----CNVNRFNVAITRAKIGILCIMSD 5879
N RFNVAITRA I +L I+ +
Sbjct 769 CLGFLSNPRRFNVAITRA-ISLLVIIGN 795
>sp|Q8EYT0|Y4133_LEPIN Macro domain-containing protein LA_4133
OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar
Lai (strain 56601) OX=189518 GN=LA_4133 PE=4 SV=1
Length=175
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 40/123 (33%), Positives = 63/123 (51%), Gaps = 11/123 (9%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN L GGGV GA+++A + +E + G VG + + + L AK +
Sbjct 20 IVNAANSSLLGGGGVDGAIHRAGGPEILEECYKIREKQGECKVGEAVITTAGRLNAKFII 79
Query 1094 HVVGPNLNAG---EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
H VGP + G ED +LL AY+N +S + P +S GI+ ++ ++ +
Sbjct 80 HTVGPIWSGGNKNED-ELLSNAYKNSLLLAKNHSLKTIAFPNISTGIYHFPKERAAKIAI 138
Query 1145 QTV 1147
Q+V
Sbjct 139 QSV 141
>sp|Q72M93|Y3295_LEPIC Macro domain-containing protein LIC_13295
OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar
copenhageni (strain Fiocruz L1-130) OX=267671 GN=LIC_13295
PE=4 SV=1
Length=175
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 40/123 (33%), Positives = 63/123 (51%), Gaps = 11/123 (9%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN L GGGV GA+++A + +E + G VG + + + L AK +
Sbjct 20 IVNAANSSLLGGGGVDGAIHRAGGPEILEECYKIREKQGECKVGEAVITTAGRLNAKFII 79
Query 1094 HVVGPNLNAG---EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
H VGP + G ED +LL AY+N +S + P +S GI+ ++ ++ +
Sbjct 80 HTVGPIWSGGNKNED-ELLSNAYKNSLLLAKNHSLKTIAFPNISTGIYHFPKERAAKIAI 138
Query 1145 QTV 1147
Q+V
Sbjct 139 QSV 141
>sp|Q8Y2K1|Y334_RALN1 Macro domain-containing protein RSc0334
OS=Ralstonia nicotianae (strain GMI1000) OX=267608 GN=RSc0334
PE=4 SV=1
Length=171
Score = 46.2 bits (108), Expect = 0.002, Method: Composition-based stats.
Identities = 41/123 (33%), Positives = 61/123 (50%), Gaps = 13/123 (11%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN L GGGV GA+++A + + L+G T G + + G L A+ +
Sbjct 23 IVNAANSALLGGGGVDGAIHRAAGPELLEACR---ALHGCRT-GQAKITPGFLLPARYII 78
Query 1094 HVVGPNLNAG--EDIQLLKAAYEN----FNSQDI--LLAPLLSAGIFGAKPLQSLQVCVQ 1145
H VGP G ++ LL A Y N D+ + P +S G++G P + + V+
Sbjct 79 HTVGPIWRGGRQDEAALLAACYRNSLALAKQHDVRTIAFPCISTGVYGFPPQLAAPIAVR 138
Query 1146 TVR 1148
TVR
Sbjct 139 TVR 141
>sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain VR-2332) OX=300559
GN=rep PE=1 SV=2
Length=3960
Score = 48.9 bits (115), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 60/248 (24%), Positives = 105/248 (42%), Gaps = 30/248 (12%)
Query 4823 DYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKS-AGFPFNKWGKA 4881
D +Y+L T + L V+ +V KY + G C ++ S AG N++
Sbjct 2744 DLSKYDLSTQGFV--LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAGINGNRFPTK 2801
Query 4882 RLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFH 4941
D S + D L A R T+T LK K + RT+ G + + +R
Sbjct 2802 ----DIQSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNFIALAHRAVL 2857
Query 4942 QKLLKS-IAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHL---MGWDYPKCDRAMPN 4997
+ + + + + +G +KF +++TP L + D CDR+ P
Sbjct 2858 SGVTQGFMKKAFNSPIALGKNKF------------KELQTPVLGRCLEADLASCDRSTPA 2905
Query 4998 MLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTA 5057
++R A+ +L + C H + N C +L V G++ K GG SSGD T+
Sbjct 2906 IVRWFAANLL---YELACAEEHLPSYVLNCCHDLL---VTQSGAV-TKRGGLSSGDPITS 2958
Query 5058 YANSVFNI 5065
+N+++++
Sbjct 2959 VSNTIYSL 2966
>sp|Q9WJC7|POLN_EEVVM Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain Mena II) OX=36384 PE=3 SV=3
Length=2499
Score = 48.9 bits (115), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 48/145 (33%), Positives = 64/145 (44%), Gaps = 26/145 (18%)
Query 1029 SANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL 1088
+A VIVNAAN + G GV GAL + ES D P+ VG + L+ G
Sbjct 1342 TATEGVIVNAANSKGQPGSGVCGALYRK-----YPESFDL----QPIEVGKARLVKGS-- 1390
Query 1089 AKKCLHVVGPNLNAGEDIQ---LLKAAYE------NFNSQDILLAPLLSAGIFGA----- 1134
+K +H VGPN + +++ L AYE N N+ + PLLS GIF
Sbjct 1391 SKHIIHAVGPNFSKVSEVEGDKQLAEAYESIAKIINDNNYRSVAIPLLSTGIFAGNKDRL 1450
Query 1135 -KPLQSLQVCVQTVRTQVYIAVNDK 1158
+ L L + T V I DK
Sbjct 1451 MQSLNHLLTALDTTDADVAIYCRDK 1475
>sp|Q93SX7|Y189_ACISE Macro domain-containing protein OS=Acinetobacter
sp. (strain ED45-25) OX=194927 PE=4 SV=1
Length=183
Score = 46.2 bits (108), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 38/126 (30%), Positives = 64/126 (51%), Gaps = 9/126 (7%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVN+AN L GGG+ ++K M++E + G G + + + NL AK +
Sbjct 19 IVNSANKSLLGGGGLDYVIHKKAGPLMKEECVRLNQEKGGCPTGQAEVTTAGNLPAKYLI 78
Query 1094 HVVGPNLNAGE--DIQLLKAAYEN--FNSQDI----LLAPLLSAGIFGAKPLQSLQVCVQ 1145
H VGP GE + QLL AY N F + +I + P +S G++G P ++ ++ +
Sbjct 79 HAVGPRWLDGEHNEPQLLCDAYSNALFKANEIHALTVSFPCISTGVYGFPPQKAAEIAIG 138
Query 1146 TVRTQV 1151
T+ + +
Sbjct 139 TILSML 144
>sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain HB-1) OX=300563
GN=rep PE=2 SV=3
Length=3961
Score = 48.5 bits (114), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 63/247 (26%), Positives = 104/247 (42%), Gaps = 28/247 (11%)
Query 4823 DYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKS-AGFPFNKWGKA 4881
D +Y+L T + L V+ +V KY + G C ++ S AG N++
Sbjct 2745 DLSKYDLVTQGFV--LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAGINGNRFPTK 2802
Query 4882 RLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFH 4941
D S + D L A R T+T LK K + RT+ G + + +R
Sbjct 2803 ----DIQSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNFIALAHR--- 2855
Query 4942 QKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHL---MGWDYPKCDRAMPNM 4998
AA G T K + + K + +++TP L + D CDR+ P +
Sbjct 2856 -------AALSGVTQGF-MKKAFNSPIALGKNKFKELQTPVLGRCLEADLASCDRSTPAI 2907
Query 4999 LRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAY 5058
+R A+ +L + C H + N C +L V G++ K GG SSGD T+
Sbjct 2908 VRWFAANLL---YELACAEEHLPSYVLNCCHDLL---VTQSGAV-TKRGGLSSGDPITSV 2960
Query 5059 ANSVFNI 5065
+N+++++
Sbjct 2961 SNTIYSL 2967
Score = 40.4 bits (93), Expect = 0.85, Method: Compositional matrix adjust.
Identities = 46/191 (24%), Positives = 75/191 (39%), Gaps = 34/191 (18%)
Query 6577 VKGLTPSKGPAQASVNGVTLIGESV----KTQFNYF--KKVDGIIQQLPETYFTQSRDLE 6630
V L P ++A + ++G SV +Y+ K V G Q LPET F+ R
Sbjct 3636 VASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVRGEAQVLPETVFSTGR--- 3692
Query 6631 DFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDS 6690
+E D E D R + + H GD +GG H + +
Sbjct 3693 -------IEVDCREYLDD----REREVAESLPHAFIGDVKGTTVGGCHHV---------T 3732
Query 6691 PLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVT 6750
L F+P +S + + ++K C++ D+ L D + + SK KV
Sbjct 3733 SKYLPRFLPKESVAVVGVSSPGE--AAKAFCTLTDVYLPDLEAYLHPE---TQSKCWKVM 3787
Query 6751 IDYAEISFMLW 6761
+D+ E+ M+W
Sbjct 3788 LDFKEVRLMVW 3798
>sp|E1SDF1|YMDB1_PANVC O-acetyl-ADP-ribose deacetylase 1 OS=Pantoea
vagans (strain C9-1) OX=712898 GN=ymdB1 PE=3 SV=1
Length=171
Score = 45.4 bits (106), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 40/136 (29%), Positives = 64/136 (47%), Gaps = 13/136 (10%)
Query 1022 DIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSC 1081
DI K + A IVNAAN L GGGV GA+++A + E G VG +
Sbjct 10 DITKVSAEA----IVNAANSSLLGGGGVDGAIHRAGGPVILAECQLIRNRQGGCKVGDAV 65
Query 1082 LLSGHNL-AKKCLHVVGPNLNAG--EDIQLLKAAYE------NFNSQDILLAPLLSAGIF 1132
+ NL A +H VGP + G ++ LLK AY+ +++ + P +S GI+
Sbjct 66 ITGAGNLPADYVIHTVGPRWSDGRHDEDALLKRAYQSCFKLVDYHGIKTVSFPNISTGIY 125
Query 1133 GAKPLQSLQVCVQTVR 1148
G ++ + + ++
Sbjct 126 GFPKERAATIALDVIK 141
>sp|Q7MTZ7|MACRO_PORGI Macro domain-containing protein PG1779
OS=Porphyromonas gingivalis (strain ATCC BAA-308 / W83) OX=242619
GN=PG_1779 PE=2 SV=1
Length=164
Score = 45.4 bits (106), Expect = 0.004, Method: Composition-based stats.
Identities = 39/122 (32%), Positives = 63/122 (52%), Gaps = 13/122 (11%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN L GGGV GA+++A + +E LNG T G S + G+NL A+ +
Sbjct 19 IVNAANHTLLGGGGVDGAIHRAAGPELLEECR---TLNGCPT-GESKITGGYNLPAQYVI 74
Query 1094 HVVGPNLNAGE--DIQLLKAAYENFNSQDI------LLAPLLSAGIFGAKPLQSLQVCVQ 1145
H VGP + G+ + +LL + Y S + + P +S G++ Q+ ++ +
Sbjct 75 HTVGPVWHGGQHGEPELLASCYRTSLSIALDKGLKSIAFPCISTGVYRYPKDQAARIALA 134
Query 1146 TV 1147
T+
Sbjct 135 TI 136
>sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhagic
fever virus OX=38143 GN=rep PE=2 SV=4
Length=3595
Score = 48.1 bits (113), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 70/290 (24%), Positives = 119/290 (41%), Gaps = 41/290 (14%)
Query 4810 FFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVI-----V 4864
++ Q G A + D ++NL T I L V+ +V Y G I I V
Sbjct 2333 YYTQHGCEAAALQDLKKFNLSTQGFI--LPEVLNIVRNYLL----GTIGYRPAIYKPSTV 2386
Query 4865 NNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRAR 4924
+ D AG + L + D D L V T+T + LK +K + R
Sbjct 2387 PSNDSHAGINGLSFSTKTL----QALPDIDELCEKAIAEVWQTVTPVTLKKQFCSKAKTR 2442
Query 4925 TVAGVSICSTMTNRQFHQKLLKSIA-ATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHL 4983
T+ G + +++ R + + A + + + +G SKF D T +
Sbjct 2443 TILGTNAMASLALRALLSGVTQGFQLAGKNSPICLGKSKF-------------DPCTFEV 2489
Query 4984 MGW----DYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCG 5039
G D CDR+ P ++R A+ +L C + Y + N C ++++
Sbjct 2490 KGRCLETDLASCDRSTPAIVRHFATKLLFEM--ACAERALPLY-VVNCC----HDLIVTQ 2542
Query 5040 GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV 5089
S K GG SSGD T+ AN+++++ V V LL +G+ ++ K++
Sbjct 2543 TSAATKRGGLSSGDPVTSIANTIYSLVLYVQHMVLTLLE-NGHPLSLKFL 2591
>sp|Q8Q0F9|Y177_METMA Macro domain-containing protein MM_0177
OS=Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1
/ Go1 / JCM 11833 / OCM 88) OX=192952 GN=MM_0177 PE=4 SV=1
Length=187
Score = 45.1 bits (105), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 49/145 (34%), Positives = 71/145 (49%), Gaps = 19/145 (13%)
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNG 1073
D + I DIVK A IVNAAN L GGGV GA+++A A+ +E LNG
Sbjct 19 DRIRIFEGDIVKMRVDA----IVNAANNTLLGGGGVDGAIHRAAGPALLEECKT---LNG 71
Query 1074 PLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAY-------ENFNSQDILL 1123
T G + + SG+ L AK +H VGP GE + +LL + Y ++ + I
Sbjct 72 CPT-GEAKITSGYLLPAKYIIHTVGPVWQGGEKGEDELLASCYRKSLELARDYKIKTIAF 130
Query 1124 APLLSAGIFGAKPLQSLQVCVQTVR 1148
P +S G +G ++ + V V+
Sbjct 131 -PAISTGAYGFPSERAAGIAVSQVK 154
>sp|A6YQT5|RPOA_PRRSV Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus OX=28344 PE=1 SV=2
Length=3931
Score = 47.4 bits (111), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 62/247 (25%), Positives = 103/247 (42%), Gaps = 28/247 (11%)
Query 4823 DYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKS-AGFPFNKWGKA 4881
D +Y+L T + L V+ +V KY + G C ++ S AG N++
Sbjct 2715 DLSKYDLSTQGFV--LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAGINGNRFPTK 2772
Query 4882 RLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFH 4941
D S + D L A R T+T LK K + RT+ G + + +R
Sbjct 2773 ----DIQSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNFIALAHR--- 2825
Query 4942 QKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHL---MGWDYPKCDRAMPNM 4998
AA G T K + + K + +++ P L + D CDR+ P +
Sbjct 2826 -------AALSGVTQGF-MKKAFNSPIALGKNKFKELQAPVLGRCLEADLASCDRSTPAI 2877
Query 4999 LRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAY 5058
+R A+ +L + C H + N C +L V G++ K GG SSGD T+
Sbjct 2878 VRWFAANLL---YELACAEEHLPSYVLNCCHDLL---VTQSGAV-TKRGGLSSGDPITSV 2930
Query 5059 ANSVFNI 5065
+N+++++
Sbjct 2931 SNTIYSL 2937
Score = 41.2 bits (95), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 46/191 (24%), Positives = 76/191 (40%), Gaps = 34/191 (18%)
Query 6577 VKGLTPSKGPAQASVNGVTLIGESV----KTQFNYF--KKVDGIIQQLPETYFTQSRDLE 6630
V L P ++A + ++G SV +Y+ K V G Q LPET F+ R
Sbjct 3606 VASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVRGEAQVLPETVFSTGR--- 3662
Query 6631 DFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDS 6690
+E D E D R + + H GD +GG H + +
Sbjct 3663 -------IEVDCREYLDD----REREVAESLPHAFIGDVKGTTVGGCHHV---------T 3702
Query 6691 PLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVT 6750
L F+P +S + + ++K VC++ D+ L D + + S+ KV
Sbjct 3703 SKYLPRFLPKESVAVVGVSSPGK--AAKAVCTLTDVYLPDLEAYLHPE---TQSRCWKVM 3757
Query 6751 IDYAEISFMLW 6761
+D+ E+ M+W
Sbjct 3758 LDFKEVRLMVW 3768
>sp|P30771|RENT1_YEAST ATP-dependent helicase NAM7 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=NAM7
PE=1 SV=1
Length=971
Score = 46.2 bits (108), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 49/208 (24%), Positives = 81/208 (39%), Gaps = 22/208 (11%)
Query 5780 VITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQ--TVDSS 5837
+IT + QIGV+ P + +I Y N K L + + +VD+
Sbjct 712 IITKLFRDGVKPEQIGVI------TPYEGQRAYILQYMQMNGSLDKDLYIKVEVASVDAF 765
Query 5838 QGSEYDYVIFTQTTETAHSC-----NVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLE 5892
QG E DY+I + + R NV +TRAK G++ + + R L + L
Sbjct 766 QGREKDYIILSCVRANEQQAIGFLRDPRRLNVGLTRAKYGLVILGNPRSLARNTLWNHLL 825
Query 5893 IPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIPKDMT 5952
I R L E + C+ + + P T ++ +F E D P +D
Sbjct 826 IHFREKGCL-VEGTLDNLQLCT--VQLVRPQPRKTERPMNAQFNVESEMGDFPKF-QDFD 881
Query 5953 YRRLISMMGFKMNYQVNGYPNMFITREE 5980
+ ++S G Q+ + N F+ E
Sbjct 882 AQSMVSFSG-----QIGDFGNAFVDNTE 904
>sp|Q88SK6|Y3408_LACPL Macro domain-containing protein lp_3408
OS=Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB
8826 / WCFS1) OX=220668 GN=lp_3408 PE=4 SV=1
Length=172
Score = 43.5 bits (101), Expect = 0.020, Method: Composition-based stats.
Identities = 53/165 (32%), Positives = 76/165 (46%), Gaps = 30/165 (18%)
Query 1016 VAIKCV--DIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNG 1073
V IK + DI K A IVNAAN L GGGV GA+++A A+ L+G
Sbjct 2 VEIKVIHGDITKMTVDA----IVNAANTSLLGGGGVDGAIHRAAGPALLAACR---PLHG 54
Query 1074 PLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENF------NSQDILLA 1124
T G + + G L AK +H GP G+ ++QLL +Y N N +
Sbjct 55 CAT-GEAKITPGFRLPAKYVIHTPGPVWQGGQHNELQLLANSYRNSLNLAAENHCQTVAF 113
Query 1125 PLLSAGIFG-----AKP--LQSLQVCVQ----TVRTQVYIAVNDK 1158
P +S G++ A P L++LQ Q TV+T + +D+
Sbjct 114 PSISTGVYHFPLSIAAPLALKTLQATAQTTAHTVQTITIVCFDDQ 158
>sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain 16244B) OX=300561
GN=rep PE=1 SV=3
Length=3961
Score = 45.8 bits (107), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 60/245 (24%), Positives = 103/245 (42%), Gaps = 24/245 (10%)
Query 4823 DYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKS-AGFPFNKWGKA 4881
D +Y+L T + L V+ +V KY + G C ++ S AG N++
Sbjct 2745 DLSKYDLSTQGFV--LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAGINGNRFPTK 2802
Query 4882 RLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFH 4941
D S + D L A R T+T LK K + RT+ G + + +R
Sbjct 2803 ----DIQSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNFIALAHRAAL 2858
Query 4942 QKLLKS-IAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLR 5000
+ + + + + +G +KF K + + V L D CDR+ P ++R
Sbjct 2859 SGVTQGFMKKAFNSPIALGKNKF--------KELQTSVLGRCLEA-DLASCDRSTPAIVR 2909
Query 5001 IMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYAN 5060
A+ +L + C H + N C +L V G++ K GG SSGD T+ +N
Sbjct 2910 WFAANLL---YELACAEEHLPSYVLNCCHDLL---VTQSGAV-TKRGGLSSGDPITSVSN 2962
Query 5061 SVFNI 5065
+++++
Sbjct 2963 TIYSL 2967
>sp|Q9ZBG3|Y6450_STRCO Macro domain-containing protein SCO6450
OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
OX=100226 GN=SCO6450 PE=4 SV=1
Length=169
Score = 43.1 bits (100), Expect = 0.025, Method: Composition-based stats.
Identities = 44/138 (32%), Positives = 67/138 (49%), Gaps = 14/138 (10%)
Query 1022 DIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI--KLNGPLTVGG 1079
DI +++ A IVNAAN L GGGV GA+++ A+ E L L G
Sbjct 10 DITRQSADA----IVNAANSSLLGGGGVDGAIHRRGGPAILAECRRLRAGHLGKGLPTGR 65
Query 1080 SCLLSGHNL-AKKCLHVVGPNLNAGEDIQ-LLKAAY-ENFNSQDILLA-----PLLSAGI 1131
+ + +L A+ +H VGP +A ED LL + Y E+ + D L A P +S G+
Sbjct 66 AVATTAGDLDARWVIHTVGPVWSATEDRSGLLASCYRESLRTADELGARTVAFPAISTGV 125
Query 1132 FGAKPLQSLQVCVQTVRT 1149
+ + ++ V+TV T
Sbjct 126 YRWPMDDAARIAVETVAT 143
>sp|O28751|Y1521_ARCFU ADP-ribose glycohydrolase AF_1521 OS=Archaeoglobus
fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628
/ NBRC 100126 / VC-16) OX=224325 GN=AF_1521 PE=1 SV=2
Length=192
Score = 43.1 bits (100), Expect = 0.036, Method: Composition-based stats.
Identities = 44/147 (30%), Positives = 71/147 (48%), Gaps = 23/147 (16%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNG-----------AMQKE-SDDYIKLNGPLTVGGSCL 1082
IVNAAN L+HGGGVA A+ KA G AM+++ DYI +G + V +
Sbjct 29 IVNAANKRLEHGGGVAYAIAKACAGDAGLYTEISKKAMREQFGRDYID-HGEVVVTPAMN 87
Query 1083 LSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF-----NSQDI----LLAPLLSAGIFG 1133
L + K H VGP + +L + Y+ F ++++ + P +SAGI+G
Sbjct 88 LEERGI-KYVFHTVGPICSGMWSEELKEKLYKAFLGPLEKAEEMGVESIAFPAVSAGIYG 146
Query 1134 AKPLQSLQVCVQTVRTQVYIAVNDKAL 1160
+ ++ ++ V+ AV + AL
Sbjct 147 CDLEKVVETFLEAVKNFKGSAVKEVAL 173
>sp|P13896|POLN_WEEV Polyprotein P1234 OS=Western equine encephalitis
virus OX=11039 PE=3 SV=3
Length=2467
Score = 45.1 bits (105), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 53/176 (30%), Positives = 77/176 (44%), Gaps = 39/176 (22%)
Query 1022 DIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSC 1081
DI K A A IVNAAN + G GV GAL + A ++ P+ VG +
Sbjct 1337 DISKSADQA----IVNAANSKGQPGSGVCGALYRKWPAAFDRQ---------PIAVGTAR 1383
Query 1082 LLSGHNLAKKCLHVVGPNLNAGEDIQ---LLKAAYENF----NSQDI--LLAPLLSAGIF 1132
L+ L +H VGPN + + + L AAY + N++ I + PLLS GI+
Sbjct 1384 LVKHEPL---IIHAVGPNFSKMPEPEGDLKLAAAYMSIASIVNAERITKISVPLLSTGIY 1440
Query 1133 GA---KPLQSLQ---VCVQTVRTQVYIAVNDK--------ALYEQVVMDYLDNLKP 1174
+ +QSL T V I DK A++ + ++ LD+ KP
Sbjct 1441 SGGKDRVMQSLHHLFTAFDTTDADVTIYCLDKQWETRIIEAIHRKESVEILDDDKP 1496
>sp|O59182|Y1513_PYRHO Uncharacterized protein PH1513 OS=Pyrococcus
horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974
/ NBRC 100139 / OT-3) OX=70601 GN=PH1513 PE=4 SV=1
Length=190
Score = 42.0 bits (97), Expect = 0.066, Method: Composition-based stats.
Identities = 46/150 (31%), Positives = 74/150 (49%), Gaps = 27/150 (18%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNG-----------AMQKE-SDDYIKLNGPLTVGGSCL 1082
IVNAAN +L+HGGGVA A+ KA +G M+++ D+I+ +G + V
Sbjct 20 IVNAANKYLEHGGGVAYAIAKAASGDVSEYTRISKEEMRRQLGKDWIE-HGEVVVTPPMK 78
Query 1083 LSGHNLAKKCLHVVGP------NLNAGEDIQL-----LKAAYENFNSQDILLAPLLSAGI 1131
L N K +H VGP + + E ++L LK A E + I P +SAGI
Sbjct 79 LK-ENGVKYVIHTVGPYCGGVWSKDKEEKLKLAILGALKKADE-LGVKSIAF-PAISAGI 135
Query 1132 FGAKPLQSLQVCVQTVRTQVYIAVNDKALY 1161
+G + ++ + V+ + +A + K +Y
Sbjct 136 YGCPLKEVVRTFKEVVKEFLKVANHVKEVY 165
>sp|Q4QXJ8|POLN_EEEVF Polyprotein P1234 OS=Eastern equine encephalitis
virus (strain Florida 91-469) OX=374598 PE=1 SV=3
Length=2494
Score = 44.3 bits (103), Expect = 0.069, Method: Compositional matrix adjust.
Identities = 45/134 (34%), Positives = 58/134 (43%), Gaps = 34/134 (25%)
Query 1022 DIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSC 1081
DI K +N VIVNAAN + G GV GAL + GA K+ P+ G +
Sbjct 1337 DITK----SNDEVIVNAANNKGQPGSGVCGALYRKWPGAFDKQ---------PVATGKAH 1383
Query 1082 LLSGHNLAKKCLHVVGPN---LNAGEDIQLLKAAY---------ENFNSQDILLAPLLSA 1129
L+ + +H VGPN L+ E Q L Y E F I PLLS
Sbjct 1384 LVKH---SPNVIHAVGPNFSRLSENEGDQKLSEVYMDIARIINNERFTKVSI---PLLST 1437
Query 1130 GIFGA---KPLQSL 1140
GI+ + +QSL
Sbjct 1438 GIYAGGKDRVMQSL 1451
>sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteritis
virus (strain Bucyrus) OX=299386 GN=rep PE=1 SV=3
Length=3175
Score = 43.9 bits (102), Expect = 0.085, Method: Compositional matrix adjust.
Identities = 43/173 (25%), Positives = 75/173 (43%), Gaps = 36/173 (21%)
Query 6596 LIGESVKTQ------FNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDE 6649
++G+SV Q + + VDG + LP++ F+ R F+ S+ FL+ A ++
Sbjct 2904 MVGQSVFVQTPGVTSYWLTEWVDGKARALPDSLFSSGR----FETNSRA---FLDEAEEK 2956
Query 6650 FIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFI 6709
F A H G+ + +GG H + SQ L +P D+ +
Sbjct 2957 FAA-------AHPHACLGEINKSTVGGSHFIF-----SQ----YLPPLLPADAVA---LV 2997
Query 6710 TDAQTG-SSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLW 6761
+ G ++K CSV+D+ F + + L S+V K+ ID+ M+W
Sbjct 2998 GASLAGKAAKAACSVVDVYAPSFEPYLHPETL---SRVYKIMIDFKPCRLMVW 3047
Score = 40.8 bits (94), Expect = 0.75, Method: Compositional matrix adjust.
Identities = 56/280 (20%), Positives = 109/280 (39%), Gaps = 55/280 (20%)
Query 4889 SYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAG--------VSICSTMTNRQF 4940
SY D + + + ++ + T T K +K + R++ G + C + F
Sbjct 2032 SYCLIDDMVSQSMKSNLQTATMATCKRQYCSKYKIRSILGTNNYIGLGLRACLSGVTAAF 2091
Query 4941 HQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETP--HLMGWDYPKCDRAMPNM 4998
+ A G+ + +G SKF + P + + D CDR+ P +
Sbjct 2092 QK------AGKDGSPIYLGKSKF------------DPIPAPDKYCLETDLESCDRSTPAL 2133
Query 4999 LRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAY 5058
+R A+ N L+ + + + ++V+ G + K GG SSGD T+
Sbjct 2134 VRWFAT-------NLIFELAGQPELVHSYVLNCCHDLVVAGSVAFTKRGGLSSGDPITSI 2186
Query 5059 ANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYL 5118
+N+++++ + L +IA+KY+ D E D F
Sbjct 2187 SNTIYSLVLYTQHMLLCGLEGYFPEIAEKYL---------------DGSLELRDMF---- 2227
Query 5119 RKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQ 5158
K+ + I SDD V+ + + A + + +A+L ++
Sbjct 2228 -KYVRVYIYSDDVVLTTPNQHYAASFDRWVPHLQALLGFK 2266
>sp|P05720|YCX1_AUXPY Uncharacterized 12.7 kDa protein in 16S-23S
DNA spacer OS=Auxenochlorella pyrenoidosa OX=3078 PE=4 SV=1
Length=110
Score = 40.0 bits (92), Expect = 0.11, Method: Composition-based stats.
Identities = 26/68 (38%), Positives = 40/68 (59%), Gaps = 5/68 (7%)
Query 492 KSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFART 551
+SL K+F ++E NYKV K K + + Q +SVL + SQ + +I +I+++
Sbjct 47 ESLTNKNFSKLIEFLDNYKVEKAKSI----TLQQLQSVLQNIKLNNSQKSEIIENIYSK- 101
Query 552 LDAANHSI 559
LDAANH I
Sbjct 102 LDAANHLI 109
>sp|Q71W03|Y2748_LISMF Macro domain-containing protein LMOf2365_2748
OS=Listeria monocytogenes serotype 4b (strain F2365)
OX=265669 GN=LMOf2365_2748 PE=4 SV=1
Length=176
Score = 41.2 bits (95), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 40/124 (32%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKC 1092
VIVNAAN L GGGV GA+++A + KE + I G G + + S +L A
Sbjct 17 VIVNAANPGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGTCPAGEAVITSAGDLQASYI 76
Query 1093 LHVVGPNLNAGEDIQLLKAAYENFNSQDI--------LLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP GE + K A + + D+ + P +S G++G + +V +
Sbjct 77 IHAVGPIWKDGEHQEANKLASCYWKALDLAAGKELTSIAFPNISTGVYGFPKKLAAEVAL 136
Query 1145 QTVR 1148
TVR
Sbjct 137 YTVR 140
>sp|Q8Y3S3|Y2759_LISMO Macro domain-containing protein lmo2759
OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679
/ EGD-e) OX=169963 GN=lmo2759 PE=4 SV=1
Length=176
Score = 40.8 bits (94), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 40/124 (32%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKC 1092
VIVNAAN L GGGV GA+++A + KE + I G G + + S +L A
Sbjct 17 VIVNAANSGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGSCPAGEAVITSAGDLKATYI 76
Query 1093 LHVVGPNLNAGEDIQLLKAAYENFNSQDI--------LLAPLLSAGIFGAKPLQSLQVCV 1144
+H VGP GE + K A + + D+ + P +S G++G + +V +
Sbjct 77 IHAVGPIWKDGEHQEANKLASCYWKALDLAAGKDLTSIAFPNISTGVYGFPKKLAAEVAL 136
Query 1145 QTVR 1148
TVR
Sbjct 137 YTVR 140
>sp|Q306W6|POLN_EEEV1 Polyprotein P1234 OS=Eastern equine encephalitis
virus (strain PE-0.0155) OX=374596 PE=1 SV=3
Length=2471
Score = 43.1 bits (100), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 52/187 (28%), Positives = 78/187 (42%), Gaps = 35/187 (19%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCL 1093
VIVNAAN + G GV GAL K GA K P+ G + L+ +
Sbjct 1345 VIVNAANNKGQPGAGVCGALYKKWPGAFDK---------APIATGTAHLVKH---TPNII 1392
Query 1094 HVVGPNLNAGEDI---QLLKAAY---------ENFNSQDILLAPLLSAGIFGA---KPLQ 1138
H VGPN + ++ Q L Y E +N I PLLS G++ + +Q
Sbjct 1393 HAVGPNFSRMSEVEGNQKLSEVYMDIAKIINKERYNKVSI---PLLSTGVYAGGKDRVMQ 1449
Query 1139 SLQ---VCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTE-E 1194
SL + T V I DK +E + D + + E + ++P + E + +
Sbjct 1450 SLNHLFTAMDTTDADVTIYCLDKQ-WETRIKDAIARKESVEELVEDDKPVDIELVRVHPQ 1508
Query 1195 KSVVQKP 1201
S+V +P
Sbjct 1509 SSLVGRP 1515
>sp|Q9V0Y3|Y656_PYRAB Uncharacterized protein PYRAB06560 OS=Pyrococcus
abyssi (strain GE5 / Orsay) OX=272844 GN=PYRAB06560
PE=4 SV=2
Length=183
Score = 40.8 bits (94), Expect = 0.17, Method: Composition-based stats.
Identities = 44/129 (34%), Positives = 62/129 (48%), Gaps = 28/129 (22%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNG-----------AMQKE-SDDYIKLNGPLTVGGSCL 1082
IVNAAN +L+HGGGVA A+ KA +G M+K+ D+I+ +G + V
Sbjct 17 IVNAANKYLEHGGGVAYAIAKAASGDVSEYIRISKEEMRKQIGRDWIE-HGEVVVTPPLN 75
Query 1083 LSGHNLAKKCLHVVGPNLNAGED-----------IQLLKAAYENFNSQDILLAPLLSAGI 1131
L+ N K +H VGP D + LK A E + I P +SAGI
Sbjct 76 LA-KNGVKYVIHTVGPYCGGKWDEDKRKKLELAILGALKKADE-LGVRSIAF-PAISAGI 132
Query 1132 FGAKPLQSL 1140
+G PL+ +
Sbjct 133 YGC-PLEEV 140
>sp|Q926Y8|Y2902_LISIN Macro domain-containing protein lin2902
OS=Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP
11262) OX=272626 GN=lin2902 PE=4 SV=1
Length=176
Score = 40.4 bits (93), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 41/127 (32%), Positives = 61/127 (48%), Gaps = 9/127 (7%)
Query 1031 NPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-A 1089
N VIVNAAN L GGGV GA+++A + KE + I G G + + S +L A
Sbjct 14 NVDVIVNAANPGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGSCPAGEAVITSAGDLKA 73
Query 1090 KKCLHVVGPNLNAGEDIQLLKAAYENFNSQDI--------LLAPLLSAGIFGAKPLQSLQ 1141
+H VGP GE + K A + + D+ + P +S G++G + +
Sbjct 74 HFIIHAVGPIWKDGEHQEANKLASCYWKALDLAAGKDLTSIAFPNISTGVYGFPKKLAAE 133
Query 1142 VCVQTVR 1148
V + TVR
Sbjct 134 VALYTVR 140
>sp|Q9UTG3|YKEE_SCHPO Uncharacterized protein C1805.14 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=SPAC1805.14
PE=4 SV=1
Length=452
Score = 42.0 bits (97), Expect = 0.22, Method: Composition-based stats.
Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 3/83 (4%)
Query 912 AGEENFSS-RMYCSFYPPDEEEEDDAECEEEEID--ETCEHEYGTEDDYQGLPLEFGASA 968
AGEE F + D + + D E E E+D + EH++G EDD+ G +
Sbjct 97 AGEETFGQIERFEYLLSSDGDGDGDVEIENPEVDDYQVSEHDFGLEDDFNGDGCQQMIEI 156
Query 969 ETVRVEEEEEEDWLDDTTEQSEI 991
E+ EEEED ++ +S++
Sbjct 157 ESDEAISEEEEDLSNENKSESQL 179
>sp|Q8P5Z8|Y3184_XANCP Macro domain-containing protein XCC3184
OS=Xanthomonas campestris pv. campestris (strain ATCC 33913
/ DSM 3586 / NCPPB 528 / LMG 568 / P 25) OX=190485 GN=XCC3184
PE=4 SV=1
Length=179
Score = 40.0 bits (92), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 37/126 (29%), Positives = 60/126 (48%), Gaps = 11/126 (9%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQK--ESDDYIKLNGPLTVGGSCLLSGHNL-AK 1090
VIVNAAN L GGGV GA+++A + + E+ ++ G + G +L A+
Sbjct 17 VIVNAANESLLGGGGVDGAIHRAAGPRLLEACEALPEVRPGVRCPTGEIRITDGFDLKAR 76
Query 1091 KCLHVVGPNLNAG---EDIQLLKAAYENFN-SQDILLA----PLLSAGIFGAKPLQSLQV 1142
H VGP G E QL +++ ++ ++L P +S GI+G Q+ ++
Sbjct 77 HIFHTVGPVWRDGKHNEPEQLANCYWQSLKLAEQMMLHSIAFPAISCGIYGYPLYQAARI 136
Query 1143 CVQTVR 1148
V R
Sbjct 137 AVTETR 142
>sp|A0A1P8ASY1|JHS1_ARATH DNA replication ATP-dependent helicase/nuclease
JHS1 OS=Arabidopsis thaliana OX=3702 GN=JHS1 PE=2
SV=1
Length=1331
Score = 42.0 bits (97), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 99/443 (22%), Positives = 167/443 (38%), Gaps = 89/443 (20%)
Query 5516 TTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLN-ISDEFSSNVANYQKV- 5573
+ + N+ FV H + + P+ I P ++ I E S N Q +
Sbjct 873 SVMRFNLMQLFVQNGHNIRKMIVDLEPPRFDNGSILSQDPAISYIWSEKSLNNDQRQAIL 932
Query 5574 ---GMQKYSTLQGPPGTGKSHFAIGL--ALYYPSARIVYTACSHAAVDALCEK----ALK 5624
+ Y+ + G PGTGK+ + AL + I+ + +++AVD L K ++
Sbjct 933 KILTAKDYALILGMPGTGKTSTMVHAVKALLIRGSSILLASYTNSAVDNLLIKLKAQGIE 992
Query 5625 YLPIDKCSRIIPARARVECFDKFK------VNSTLEQYVFCTVNALPETTA-------DI 5671
+L I + + R CF + L+Q L + D+
Sbjct 993 FLRIGR-DEAVHEEVRESCFSAMNMCSVEDIKKKLDQVKVVASTCLGINSPLLVNRRFDV 1051
Query 5672 VVFDEISMATNYDLSV-VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM 5730
+ DE A L V + L A +V +GD QLP P T+ E S+ R +
Sbjct 1052 CIIDE---AGQIALPVSIGPLLFASTFVLVGDHYQLP-PLVQSTEAR-ENGMGISLFRRL 1106
Query 5731 KTIGPD---MFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSA----------------- 5770
P + R C I++ +AL+Y ++L + A
Sbjct 1107 SEAHPQAISVLQNQYRMCRG-IMELSNALIYGDRLCCGSAEVADATLVLSTSSSTSPWLK 1165
Query 5771 -----------------QCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV-F 5812
+ F+ + I + V ++I I + E L N K +
Sbjct 1166 KVLEPTRTVVFVNTDMLRAFEARDQNAINNPVEASI----IAEIVEELVNNGVDSKDIGI 1221
Query 5813 ISPYNSQNAVASKILGLPT-----QTVDSSQGSEYDYVI--FTQTTETAHSC------NV 5859
I+PYNSQ ++ +PT T+D QG + D ++ F ++ E S +
Sbjct 1222 ITPYNSQASLIQH--AIPTTPVEIHTIDKYQGRDKDCILVSFVRSREKPRSSASSLLGDW 1279
Query 5860 NRFNVAITRAKIGILCIMSDRDL 5882
+R NVA+TRAK ++ + S R L
Sbjct 1280 HRINVALTRAKKKLIMVGSQRTL 1302
>sp|Q8TQD0|Y1614_METAC Macro domain-containing protein MA_1614
OS=Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834
/ JCM 12185 / C2A) OX=188937 GN=MA_1614 PE=4 SV=1
Length=195
Score = 40.4 bits (93), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 66/135 (49%), Gaps = 19/135 (14%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKC 1092
IVNAAN L GGGV GA+++A + +E LNG T G + + G+ L AK
Sbjct 43 AIVNAANNTLLGGGGVDGAIHRAAGPGLLEECRT---LNGCPT-GEAKITKGYLLPAKYV 98
Query 1093 LHVVGP---NLNAGEDIQLLKAAY-------ENFNSQDILLAPLLSAGIFGAKPLQSLQV 1142
+H VGP GED + L + Y ++ + I P +S G +G ++ ++
Sbjct 99 IHTVGPIWQEGTKGED-EFLASCYRKSLELARKYDVKTIAF-PTISTGAYGFPSERAARI 156
Query 1143 CVQTVRTQVYIAVND 1157
V V+ ++ VN+
Sbjct 157 AVSQVKE--FLKVNE 169
>sp|Q9HXU7|Y3693_PSEAE Macro domain-containing protein PA3693
OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP
104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964
GN=PA3693 PE=4 SV=1
Length=173
Score = 39.7 bits (91), Expect = 0.40, Method: Composition-based stats.
Identities = 41/139 (29%), Positives = 61/139 (44%), Gaps = 19/139 (14%)
Query 1022 DIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSC 1081
DI + A A IVNAAN L GGGV GA+++A + +L G +
Sbjct 10 DITRLAVDA----IVNAANSSLLGGGGVDGAIHRAAGAELVAAC----RLLHGCKTGEAK 61
Query 1082 LLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAY-------ENFNSQDILLAPLLSAGI 1131
+ G L A +H VGP G+ + +LL + Y E + + P +S GI
Sbjct 62 ITRGFRLPAAHVIHTVGPVWRGGDNGEAELLASCYRRSLALAEQAGAASVAF-PAISCGI 120
Query 1132 FGAKPLQSLQVCVQTVRTQ 1150
+G Q+ + V+ V Q
Sbjct 121 YGYPLEQAAAIAVEEVCRQ 139
>sp|Q8K4G6|MACD1_RAT ADP-ribose glycohydrolase MACROD1 (Fragment)
OS=Rattus norvegicus OX=10116 GN=Macrod1 PE=2 SV=2
Length=258
Score = 40.4 bits (93), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 39/126 (31%), Positives = 61/126 (48%), Gaps = 16/126 (13%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKC 1092
IVNAAN L GGGV G +++A + +D+ L T G + + G+ L AK
Sbjct 101 AIVNAANNSLLGGGGVDGCIHRAAGSLL---TDECRTLQNCET-GKAKITCGYRLPAKHV 156
Query 1093 LHVVGPNLNAGEDIQLLKAAYEN--FNSQDILLA--------PLLSAGIFGAKPLQSLQV 1142
+H VGP + G+ A + +S D+LL P +S G+FG ++ +V
Sbjct 157 IHTVGP-IAVGQPTASQAAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPNEEAAEV 215
Query 1143 CVQTVR 1148
+ T+R
Sbjct 216 VLATLR 221
>sp|Q9BQ69|MACD1_HUMAN ADP-ribose glycohydrolase MACROD1 OS=Homo
sapiens OX=9606 GN=MACROD1 PE=1 SV=2
Length=325
Score = 40.4 bits (93), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 46/161 (29%), Positives = 75/161 (47%), Gaps = 24/161 (15%)
Query 1000 EEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNG 1059
EEP ++ +L + +++ DI K A IVNAAN L GGGV G +++A
Sbjct 140 EEP--RYKKDKQLNEKISLLRSDITKLEVDA----IVNAANSSLLGGGGVDGCIHRAAGP 193
Query 1060 AMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGP---NLNAGEDIQLLKAAYEN 1115
+ +D+ L T G + + G+ L AK +H VGP + L++ Y
Sbjct 194 LL---TDECRTLQSCKT-GKAKITGGYRLPAKYVIHTVGPIAYGEPSASQAAELRSCY-- 247
Query 1116 FNSQDILLA--------PLLSAGIFGAKPLQSLQVCVQTVR 1148
+S D+LL P +S G+FG + ++ + T+R
Sbjct 248 LSSLDLLLEHRLRSVAFPCISTGVFGYPCEAAAEIVLATLR 288
>sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens
OX=9606 GN=SETX PE=1 SV=4
Length=2677
Score = 41.2 bits (95), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 61/242 (25%), Positives = 97/242 (40%), Gaps = 45/242 (19%)
Query 5693 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV----CRLMK--------TIGPDMFLG 5740
R + +GDP QLP T+++ E Y S+ CRL++ + P + L
Sbjct 2198 RCNKLILVGDPKQLPP--TVISMKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQLT 2255
Query 5741 TCRRCPAEIVDTVSALVYDNKLKAHKDKSA---------QCFKMFY--KGVITHDVSSAI 5789
R +I S VY+ LK ++ A Q + +F G D S I
Sbjct 2256 VQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSDWPFQPYLVFDVGDGSERRDNDSYI 2315
Query 5790 NRPQIGVVREFLT------RNPAWRKAVFISPYNSQNAVASKILGL------PTQ--TVD 5835
N +I +V E + ++ ++R I+ Y +Q + K L P + TVD
Sbjct 2316 NVQEIKLVMEIIKLIKDKRKDVSFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVD 2375
Query 5836 SSQGSEYDYVIFTQTTETAHS------CNVNRFNVAITRAKIGILCIMSDRDLYDKLQFT 5889
+ QG + D VI T + ++ R NV ITRAK + + R L + +
Sbjct 2376 AFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWN 2435
Query 5890 SL 5891
L
Sbjct 2436 QL 2437
>sp|Q9BYK8|HELZ2_HUMAN 3'-5' exoribonuclease HELZ2 OS=Homo sapiens
OX=9606 GN=HELZ2 PE=1 SV=7
Length=2896
Score = 41.2 bits (95), Expect = 0.54, Method: Compositional matrix adjust.
Identities = 28/91 (31%), Positives = 44/91 (48%), Gaps = 25/91 (27%)
Query 5813 ISPYNSQNAVASKIL------GLPTQTVDSSQGSEYDYVIFTQTTETAHS---------- 5856
++PYN+Q + SK L G+ ++ SQGSE+ YV+ + A S
Sbjct 2768 LTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSW 2827
Query 5857 --------CNVNRFNVAITRAKIGILCIMSD 5879
+ N+ NVA+TRA+ G LC++ D
Sbjct 2828 LKKFLGFVVDPNQVNVAVTRAQEG-LCLIGD 2857
>sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 homolog
OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A /
CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=2E4.130 PE=3
SV=1
Length=1093
Score = 40.8 bits (94), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 28/87 (32%), Positives = 46/87 (53%), Gaps = 9/87 (10%)
Query 5538 APTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLA 5597
APT + + GL P LN +S +A ++V S +QGPPGTGK+ + +
Sbjct 438 APTKITMPKKFHVPGL-PELN-----ASQIAAIKQVLSNPLSLIQGPPGTGKTVTSATII 491
Query 5598 LY---YPSARIVYTACSHAAVDALCEK 5621
+ +++++ A S+ AVD LCE+
Sbjct 492 YHLAKMSNSQVLVCAPSNVAVDQLCER 518
>sp|Q9RUV0|PPDE_DEIRA Phosphatase/phosphodiesterase DR_1281 OS=Deinococcus
radiodurans (strain ATCC 13939 / DSM 20539 / JCM
16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 /
VKM B-1422 / R1) OX=243230 GN=DR_1281 PE=1 SV=1
Length=255
Score = 39.7 bits (91), Expect = 0.68, Method: Composition-based stats.
Identities = 54/177 (31%), Positives = 74/177 (42%), Gaps = 31/177 (18%)
Query 2835 ITREIGFIVPGLPGTVLRA--INGDFL---HFLPRVF-SAVGNICYTPSKLIEYSDFATS 2888
I R + + PG PG R +NG+ L + L RVF AV N T L+E D T
Sbjct 84 IVRPLNYADPGTPGVGWRTFDVNGEKLTVVNLLGRVFMEAVDNPFRTMDALLERDDLGTV 143
Query 2889 ACVLAAECTIFKDAMG--------------KPVPYCYDTNLLEGSISYSELRPDTRYVLM 2934
AE T K+AMG VP DT +L+G +Y + D +
Sbjct 144 FVDFHAEATSEKEAMGWHLAGRVAAVIGTHTHVPTA-DTRILKGGTAY---QTDAGFTGP 199
Query 2935 DGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCE-RSEV-GICLSTSGRWVLNNEHYR 2989
SII + +EG ++ T R+G E R+E+ G+ L G E YR
Sbjct 200 HDSII---GSAIEGPLQRFLTERPH--RYGVAEGRAELNGVALHFEGGKATAAERYR 251
>sp|A2AKX3|SETX_MOUSE Probable helicase senataxin OS=Mus musculus
OX=10090 GN=Setx PE=1 SV=1
Length=2646
Score = 40.8 bits (94), Expect = 0.77, Method: Compositional matrix adjust.
Identities = 62/242 (26%), Positives = 101/242 (42%), Gaps = 45/242 (19%)
Query 5693 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV----CRLMKT------IG--PDMFLG 5740
R + +GDP QLP T+++ E Y S+ C+L++ IG P + L
Sbjct 2174 RCNKLILVGDPKQLPP--TVISMKAQEYGYDQSMMARFCKLLEENVEQNMIGRLPVLQLT 2231
Query 5741 TCRRCPAEIVDTVSALVYDNKLKAHK-DKSAQC-----FKMFY-----KGVITHDVSSAI 5789
R +I S VY+ LK ++ +S +C F+ + G D S I
Sbjct 2232 IQYRMHPDICLFPSNYVYNKNLKTNRLTESIRCSSEWPFQPYLVFDVGDGSERRDNDSYI 2291
Query 5790 NRPQIGVVREFLT------RNPAWRKAVFISPYNSQNAVASKILGL------PTQ--TVD 5835
N +I +V E + ++ ++R I+ Y +Q + K L P + TVD
Sbjct 2292 NVQEIKLVMEIIKLIKEKRKDISFRNIGIITHYKAQKTMIQKDLEKEFDKKGPAEVDTVD 2351
Query 5836 SSQGSEYDYVIFTQTTETAHS------CNVNRFNVAITRAKIGILCIMSDRDLYDKLQFT 5889
+ QG + D +I T +A ++ R NV ITRAK + + R L + +
Sbjct 2352 AFQGRQKDCIIVTCVRASAVQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWY 2411
Query 5890 SL 5891
L
Sbjct 2412 EL 2413
>sp|Q09449|YQ12_CAEEL Uncharacterized ATP-dependent helicase C05C10.2
OS=Caenorhabditis elegans OX=6239 GN=C05C10.2 PE=3 SV=2
Length=1523
Score = 40.4 bits (93), Expect = 0.80, Method: Compositional matrix adjust.
Identities = 56/204 (27%), Positives = 84/204 (41%), Gaps = 35/204 (17%)
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMF----LGTCRRCPAEIVDTVSA 5755
IGD QLP +G L+ F + + I MF L RC + + +S
Sbjct 1206 IGDIHQLPPYCEEGLEGKLKD--FGIGNTMERAIKEKMFPVCTLRNVYRCHPKTTELLSE 1263
Query 5756 LVYDNKLKAHKDKSAQC--------------FKMFY---KGVITHDVSSAINRPQIGVVR 5798
L YD L + + A+ F M + G T +S N + +V
Sbjct 1264 LFYDGALVSGVSELARSDFMTKRDDFWPNPKFPMMFVNNTGASTKMGTSTSNSSEKSIVG 1323
Query 5799 EFLT------RNPAWRKAV-FISPYNSQNAVASKIL---GLPTQTVDSSQGSEYDYVIFT 5848
E + RNP + IS Y++Q ++ ++ L G+ TVD+ QGSE + +I
Sbjct 1324 EIVQNLINDPRNPVNPSDIGVISFYSAQTSILTEHLRGSGVKCGTVDAFQGSEKEIIIMC 1383
Query 5849 QTTETAHSCN--VNRFNVAITRAK 5870
T E NR NVA++RAK
Sbjct 1384 STNERISDFMQLSNRLNVAMSRAK 1407
>sp|Q97AU0|Y719_THEVO Uncharacterized protein TV0719 OS=Thermoplasma
volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 /
NBRC 15438 / GSS1) OX=273116 GN=TV0719 PE=4 SV=1
Length=186
Score = 38.9 bits (89), Expect = 0.80, Method: Compositional matrix adjust.
Identities = 38/115 (33%), Positives = 54/115 (47%), Gaps = 14/115 (12%)
Query 1031 NPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP--LTVGGSCLLSGHNL 1088
N IVNAAN L GGGV GA++ + E + + P L G + + SG L
Sbjct 22 NCEAIVNAANPSLMGGGGVDGAIHLKGGKTIDLECAELRRTKWPKGLPPGEADITSGGKL 81
Query 1089 -AKKCLHVVGPNLNAG-EDIQLLKAAYENFNSQDI--------LLAPLLSAGIFG 1133
AK +H VGP ED + L ++Y + S +I + P +S GI+G
Sbjct 82 KAKYVIHTVGPIYRGQEEDAETLYSSY--YRSLEIAKIHGIKCIAFPAISTGIYG 134
>sp|Q8PHB6|Y3343_XANAC Macro domain-containing protein XAC3343
OS=Xanthomonas axonopodis pv. citri (strain 306) OX=190486
GN=XAC3343 PE=4 SV=2
Length=179
Score = 38.5 bits (88), Expect = 0.83, Method: Composition-based stats.
Identities = 36/126 (29%), Positives = 58/126 (46%), Gaps = 11/126 (9%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQK--ESDDYIKLNGPLTVGGSCLLSGHNL-AK 1090
VIVNAAN L GGGV GA+++A + + E+ ++ G + G +L A+
Sbjct 17 VIVNAANESLLGGGGVDGAIHRAAGPRLLEACEALPQVRPGVRCPTGEIRITDGFDLKAR 76
Query 1091 KCLHVVGPNLNAG---EDIQLLKAAYENFNSQDILLA-----PLLSAGIFGAKPLQSLQV 1142
H VGP G E QL +++ + ++ P +S GI+G Q+ ++
Sbjct 77 HIFHTVGPVWRDGRHNEPEQLANCYWQSLKLAEQMMLHSIAFPAISCGIYGYPLHQAARI 136
Query 1143 CVQTVR 1148
V R
Sbjct 137 AVTETR 142
>sp|Q09820|RENT1_SCHPO ATP-dependent helicase upf1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=upf1
PE=3 SV=2
Length=925
Score = 40.4 bits (93), Expect = 0.85, Method: Compositional matrix adjust.
Identities = 43/187 (23%), Positives = 73/187 (39%), Gaps = 29/187 (16%)
Query 5775 MFYKGVITHDVSSA----INRPQIG----VVREFLTRNPAWRKAVFISPYNSQ------- 5819
MFY ++S++ +NR + +V FL N + ++PY+ Q
Sbjct 675 MFYANFGQEELSASGTSFLNRTEASTCEKIVTTFLRSNVLPEQIGIVTPYDGQRSYIVQY 734
Query 5820 ---NAVASKIL--GLPTQTVDSSQGSEYDYVIFTQTTETAHSC-----NVNRFNVAITRA 5869
N K L + +VD+ QG E D++I + + H + R NVA+TRA
Sbjct 735 MQNNGSMQKDLYKAVEVASVDAFQGREKDFIILSCVRSSEHQGIGFVNDPRRLNVALTRA 794
Query 5870 KIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHL 5929
K G++ + + + L + + + L V G K L P Q P
Sbjct 795 KYGVIVLGNPKVLAKHALWYHFVLHCKEKGYL----VEGTLNSLQKFSLTLTPPQKPQKF 850
Query 5930 SVDIKFK 5936
D+ +
Sbjct 851 KRDLNVQ 857
>sp|Q306W8|POLN_EEEV8 Polyprotein P1234 OS=Eastern equine encephalitis
virus (strain PE-3.0815) OX=374597 PE=1 SV=3
Length=2474
Score = 40.4 bits (93), Expect = 0.85, Method: Compositional matrix adjust.
Identities = 43/134 (32%), Positives = 55/134 (41%), Gaps = 34/134 (25%)
Query 1022 DIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSC 1081
DI K A IVNAAN + G GV GAL K GA K P+ G +
Sbjct 1337 DISKSTDEA----IVNAANNKGQPGAGVCGALYKKWPGAFDKV---------PIATGTAH 1383
Query 1082 LLSGHNLAKKCLHVVGPNLNAGEDI---QLLKAAY---------ENFNSQDILLAPLLSA 1129
L+ +H VGPN + ++ Q L Y E +N I PLLS
Sbjct 1384 LVKH---TPNIIHAVGPNFSRVSEVEGNQKLSEVYMDIAKIINRERYNKVSI---PLLST 1437
Query 1130 GIFGA---KPLQSL 1140
GI+ + +QSL
Sbjct 1438 GIYAGGKDRVMQSL 1451
>sp|P18479|POLG_ZYMVC Genome polyprotein OS=Zucchini yellow mosaic
virus (strain California) OX=117128 PE=1 SV=2
Length=3080
Score = 40.4 bits (93), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 43/192 (22%), Positives = 78/192 (41%), Gaps = 37/192 (19%)
Query 4823 DYYRYNLP---TMCDIRQLLFVVEVVDKY---FDCYDGGCINANQVIVNNLDKSAGFPFN 4876
D+++YN P D + L V+ V + F+ + I + I N+L+ A
Sbjct 2356 DFFKYNKPVTVNQLDHDKFLGAVDGVIRMMCDFEFNECRFITDPEEIYNSLNMKAAIGAQ 2415
Query 4877 KWGKARLYYDSMS-YEDQDALFAYTKR--NVIPTITQMNLKYAISAKNRAR--------- 4924
GK + Y++ + ++ + LF +R N + +LK + + R
Sbjct 2416 YRGKKKEYFEGLDDFDRERLLFQSCERLFNGYKGLWNGSLKAELRPLEKVRANKTRTFTA 2475
Query 4925 ----TVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
T+ G +C N +F++K LK +G +KFYGGW +++++
Sbjct 2476 APIDTLLGAKVCVDDFNNEFYRKNLK-------CPWTVGMTKFYGGWDKLMRSLPD---- 2524
Query 4981 PHLMGWDYPKCD 4992
GW Y D
Sbjct 2525 ----GWLYCHAD 2532
>sp|Q9HJ67|Y1105_THEAC Uncharacterized protein Ta1105 OS=Thermoplasma
acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062
/ NBRC 15155 / AMRC-C165) OX=273075 GN=Ta1105 PE=4 SV=2
Length=196
Score = 38.9 bits (89), Expect = 0.88, Method: Composition-based stats.
Identities = 41/144 (28%), Positives = 66/144 (46%), Gaps = 17/144 (12%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP- 1074
+A++ DI + A IVNAAN L GGGV GA++ A + E + P
Sbjct 11 LAVEVGDITESDAEA----IVNAANSSLMGGGGVDGAIHSAAGPELNGELVKIRRERYPN 66
Query 1075 -LTVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQ--LLKAAYEN-------FNSQDILL 1123
L G + + G+ L A +H VGP G + + +L +Y + F DI
Sbjct 67 GLPPGEAVITRGYRLKASHIIHTVGPVWMGGRNGEDDVLYRSYRSCLDLAREFGIHDIAF 126
Query 1124 APLLSAGIFGAKPLQSLQVCVQTV 1147
P LS G +G ++ ++ +++V
Sbjct 127 -PALSTGAYGFPFDRAERIAIRSV 149
>sp|Q6PAV8|MACD2_XENLA ADP-ribose glycohydrolase MACROD2 OS=Xenopus
laevis OX=8355 GN=macrod2 PE=2 SV=1
Length=418
Score = 40.0 bits (92), Expect = 0.93, Method: Composition-based stats.
Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 22/128 (17%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVNAAN L GGGV G +++A+ ++ E + G G + + G+ L AK +
Sbjct 85 IVNAANTSLLGGGGVDGCIHRASGPSLLAECREL----GGCETGQAKITCGYELPAKYVI 140
Query 1094 HVVGP------NLNAGEDI-----QLLKAAYENFNSQDI--LLAPLLSAGIFGAKPLQSL 1140
H VGP N +D+ L A EN DI + P +S GI+G +
Sbjct 141 HTVGPIARGHITPNHKQDLASCYNSSLTLATEN----DIRTIAFPCISTGIYGYPNEPAA 196
Query 1141 QVCVQTVR 1148
V + TV+
Sbjct 197 NVALTTVK 204
>sp|Q9FJR0|RENT1_ARATH Regulator of nonsense transcripts 1 homolog
OS=Arabidopsis thaliana OX=3702 GN=UPF1 PE=1 SV=2
Length=1254
Score = 40.4 bits (93), Expect = 0.96, Method: Compositional matrix adjust.
Identities = 33/119 (28%), Positives = 56/119 (47%), Gaps = 18/119 (15%)
Query 5780 VITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL--GLPTQTVDSS 5837
++T + S + QIGV+ P + +I Y ++N + L + +VDS
Sbjct 796 LVTAFLKSGVVPSQIGVI------TPYEGQRAYIVNYMARNGSLRQQLYKEIEVASVDSF 849
Query 5838 QGSEYDYVIFTQTTETAHSC-----NVNRFNVAITRAKIGILC-----IMSDRDLYDKL 5886
QG E DY+I + H + R NVA+TRA+ GI+ ++S + L++ L
Sbjct 850 QGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVILGNPKVLSKQPLWNGL 908
>sp|P32644|ECM32_YEAST Putative ATP-dependent RNA helicase ECM32
OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=ECM32 PE=1 SV=1
Length=1121
Score = 40.0 bits (92), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 26/63 (41%), Positives = 35/63 (56%), Gaps = 5/63 (8%)
Query 5819 QNAVASKILGLPTQTVDSSQGSEYDYVIFT---QTTETAHSC--NVNRFNVAITRAKIGI 5873
QN V + I GL TVDS QG E ++IF+ TE + R NVA+TRAK G+
Sbjct 1026 QNNVINIINGLHVATVDSFQGHEKSFIIFSCVRNNTENKIGFLRDKRRLNVALTRAKHGL 1085
Query 5874 LCI 5876
+ +
Sbjct 1086 IVV 1088
>sp|Q922B1|MACD1_MOUSE ADP-ribose glycohydrolase MACROD1 OS=Mus
musculus OX=10090 GN=Macrod1 PE=1 SV=2
Length=323
Score = 39.3 bits (90), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 43/149 (29%), Positives = 71/149 (48%), Gaps = 20/149 (13%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+L + +++ DI K A IVNAAN L GGGV G +++A + +D+
Sbjct 147 QLNEKISLYRGDITKLEVDA----IVNAANSSLLGGGGVDGCIHRAAGSLL---TDECRT 199
Query 1071 LNGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQLLKAAYEN--FNSQDILLA--- 1124
L T G + + G+ L AK +H VGP + G+ A + +S D+LL
Sbjct 200 LQNCET-GKAKITCGYRLPAKYVIHTVGP-IAVGQPTASQAAELRSCYLSSLDLLLEHRL 257
Query 1125 -----PLLSAGIFGAKPLQSLQVCVQTVR 1148
P +S G+FG ++ +V + ++R
Sbjct 258 RSVAFPCISTGVFGYPNEEAAEVVLASLR 286
>sp|Q9EYI6|Y189_STRNO Macro domain-containing protein in sno 5'region
OS=Streptomyces nogalater OX=38314 PE=4 SV=1
Length=181
Score = 38.1 bits (87), Expect = 1.2, Method: Composition-based stats.
Identities = 42/138 (30%), Positives = 65/138 (47%), Gaps = 14/138 (10%)
Query 1022 DIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDY--IKLNGPLTVGG 1079
DI ++ A +VNAAN L GGGV GA+++ A+ E + L G
Sbjct 10 DITRQHADA----LVNAANSSLLGGGGVDGAIHRRGGPAILAECRALRASRYGEGLPTGR 65
Query 1080 SCLLSGHNL-AKKCLHVVGPNLNAGED-IQLLKAAY-ENFNSQDILLA-----PLLSAGI 1131
+ + +L A+ +H VGP ++ ED LL + Y E+ L A P LS G+
Sbjct 66 AVATTAGDLDARWVIHTVGPVWSSTEDRSDLLASCYRESLRLAGELGARTVAFPALSTGV 125
Query 1132 FGAKPLQSLQVCVQTVRT 1149
+ + ++ V+TVRT
Sbjct 126 YRWPMGDAARIAVETVRT 143
>sp|Q180E9|TIG_CLOD6 Trigger factor OS=Clostridioides difficile
(strain 630) OX=272563 GN=tig PE=3 SV=1
Length=428
Score = 39.7 bits (91), Expect = 1.2, Method: Composition-based stats.
Identities = 45/180 (25%), Positives = 82/180 (46%), Gaps = 29/180 (16%)
Query 1102 AGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALY 1161
AGE++++ E ++SQD+ P+ +F K + V+ + A++D+
Sbjct 209 AGEEVEVNVTFPEEYHSQDLAGKPV----VFNVK--------INDVKVKELSALDDEFAK 256
Query 1162 EQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK----------PVDVKPKIKAC 1211
+ D LD LK V A +EE N D++T SVV+K V ++ +I
Sbjct 257 DTSEFDSLDELKADVRAKLEEEAKNRADAET-RNSVVEKVAENTEIEIPEVMIQHQIDNM 315
Query 1212 IDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGD 1271
++E+ L+ F +LL ++ G+ + + R ED L K + +V + IT +
Sbjct 316 LNELNYQLQYQGFGLQQLL---EMTGRTMEELREE-RKEDAKKLVKSS--LVLEAITKAE 369
>sp|P26627|R1AB_CVMJD Replicase polyprotein 1ab (Fragment) OS=Murine
coronavirus (strain defective JHM) OX=11143 GN=rep PE=3
SV=1
Length=500
Score = 39.7 bits (91), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 43/182 (24%), Positives = 76/182 (42%), Gaps = 13/182 (7%)
Query 1573 PTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSE-AFEYYHTLDESFLGRYMSALNHTK 1631
P ++ D+ K++ + E +T P+D T AF+ ++ S S H K
Sbjct 316 PDQVEAFDIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPSDETHFK 375
Query 1632 KWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALI 1691
V G S NC+L S L+ +Q L ++F +Q+ + +AG F +
Sbjct 376 ------VCGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKL 429
Query 1692 LAYSNKTV--GELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMG 1749
+ + K++ + G V + L + K N C CG + L G++AV + G
Sbjct 430 VKSAPKSIILPQGGYVADFAYFFLSQCSF---KVHANWRCLKCGME-LKLQGLDAVFFYG 485
Query 1750 TL 1751
+
Sbjct 486 DV 487
>sp|C4L602|RIMM_EXISA Ribosome maturation factor RimM OS=Exiguobacterium
sp. (strain ATCC BAA-1283 / AT1b) OX=360911 GN=rimM
PE=3 SV=1
Length=172
Score = 37.7 bits (86), Expect = 1.7, Method: Composition-based stats.
Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 11/86 (13%)
Query 2770 VHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCP 2829
VH L H+ Y +EIIG +A+ DG ++ DD F A D W +R G K+D P
Sbjct 89 VHDLDEHEFYYHEIIGCEAVVDGEVIGVV--DDIFETNGAN-DVWVIKRPG--KSDALIP 143
Query 2830 VVAAIITREIG-----FIVPGLPGTV 2850
+ +++ +EI ++ +PG +
Sbjct 144 YIESVV-QEIDVDAKRVVITPIPGMI 168
>sp|O40955|POLN_RUBVR Non-structural polyprotein p200 OS=Rubella
virus (strain RA27/3 vaccine) OX=11044 PE=1 SV=1
Length=2116
Score = 39.3 bits (90), Expect = 2.1, Method: Composition-based stats.
Identities = 56/228 (25%), Positives = 85/228 (37%), Gaps = 35/228 (15%)
Query 984 DTTEQSEIEPEPEP------TPEEPVNQFT-GYLKLTDNVAIKCVDIVKEAQSANPMVIV 1036
D +E+E EP T +P + Y + V ++ DI+ V+V
Sbjct 780 DRARDAELEVAYEPSGPPTSTKADPDSDIVESYARAAGPVHLRVRDIMDPPPGCK--VVV 837
Query 1037 NAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA-KKCLHV 1095
NAAN L G GV GA+ A+ + + P G + GH +H
Sbjct 838 NAANEGLLAGSGVCGAIFANATAALAADC----RRLAPCPTGEAVATPGHGCGYTHIIHA 893
Query 1096 VGPN-------LNAGEDIQLLKAAYENFNSQDILLA------PLLSAGIFGAKPLQSLQV 1142
V P L GE LL+ AY + + PLL AG++G +SL+
Sbjct 894 VAPRRPRDPAALEEGE--ALLERAYRSIVALAAARRWARVACPLLGAGVYGWSAAESLRA 951
Query 1143 CVQTVRTQ------VYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEP 1184
+ RT+ ++I D+A + L R +P EP
Sbjct 952 ALAATRTEPAERVSLHICHPDRATLTHASVLVGAGLAARRVSPPPTEP 999
>sp|Q8BCR0|POLN_RUBVN Non-structural polyprotein p200 OS=Rubella
virus (strain RN-UK86) OX=376267 PE=3 SV=1
Length=2116
Score = 39.3 bits (90), Expect = 2.2, Method: Composition-based stats.
Identities = 56/228 (25%), Positives = 85/228 (37%), Gaps = 35/228 (15%)
Query 984 DTTEQSEIEPEPEP------TPEEPVNQFT-GYLKLTDNVAIKCVDIVKEAQSANPMVIV 1036
D +E+E EP T +P + Y + V ++ DI+ V+V
Sbjct 780 DRARHAELEVVYEPSGPPTSTKADPDSDIVESYARAAGPVHLRVRDIMDPPPGCK--VVV 837
Query 1037 NAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA-KKCLHV 1095
NAAN L G GV GA+ A+ + + P G + GH +H
Sbjct 838 NAANEGLLAGSGVCGAIFANATAALAADC----RRLAPCPTGEAVATPGHGCGYTHIIHA 893
Query 1096 VGPN-------LNAGEDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQV 1142
V P L GE LL+ AY + + PLL AG++G +SL+
Sbjct 894 VAPRRPRDPAALEEGE--ALLERAYRSIVALAAARRWACVACPLLGAGVYGWSAAESLRA 951
Query 1143 CVQTVRTQ------VYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEP 1184
+ RT+ ++I D+A + L R +P EP
Sbjct 952 ALAATRTEPAERVSLHICHPDRATLTHASVLVGAGLAARRVSPPPTEP 999
>sp|Q7TZB9|Y1934_MYCBO Uncharacterized protein Mb1934c OS=Mycobacterium
bovis (strain ATCC BAA-935 / AF2122/97) OX=233413
GN=lppD PE=4 SV=1
Length=358
Score = 38.5 bits (88), Expect = 2.3, Method: Composition-based stats.
Identities = 23/79 (29%), Positives = 40/79 (51%), Gaps = 5/79 (6%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
I NAAN L+H GGVA A+ +A +Q+ES + P+ +G + + ++ A+ +
Sbjct 206 ITNAANTRLRHAGGVAAAIARAGGPELQRESTE----KAPIGLGEAVETTAGDMPARYVI 261
Query 1094 HVVGPNLNAGEDIQLLKAA 1112
H L +++ AA
Sbjct 262 HAATMELGGPTSGEIITAA 280
>sp|P9WK29|Y1899_MYCTU Uncharacterized protein Rv1899c OS=Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv) OX=83332
GN=Rv1899c PE=1 SV=1
Length=359
Score = 38.5 bits (88), Expect = 2.3, Method: Composition-based stats.
Identities = 23/79 (29%), Positives = 40/79 (51%), Gaps = 5/79 (6%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
I NAAN L+H GGVA A+ +A +Q+ES + P+ +G + + ++ A+ +
Sbjct 207 ITNAANTRLRHAGGVAAAIARAGGPELQRESTE----KAPIGLGEAVETTAGDMPARYVI 262
Query 1094 HVVGPNLNAGEDIQLLKAA 1112
H L +++ AA
Sbjct 263 HAATMELGGPTSGEIITAA 281
>sp|P9WK28|Y1899_MYCTO Uncharacterized protein MT1950 OS=Mycobacterium
tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=MT1950
PE=4 SV=1
Length=374
Score = 38.5 bits (88), Expect = 2.3, Method: Composition-based stats.
Identities = 23/79 (29%), Positives = 40/79 (51%), Gaps = 5/79 (6%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
I NAAN L+H GGVA A+ +A +Q+ES + P+ +G + + ++ A+ +
Sbjct 222 ITNAANTRLRHAGGVAAAIARAGGPELQRESTE----KAPIGLGEAVETTAGDMPARYVI 277
Query 1094 HVVGPNLNAGEDIQLLKAA 1112
H L +++ AA
Sbjct 278 HAATMELGGPTSGEIITAA 296
>sp|Q2KHU5|MACD1_BOVIN ADP-ribose glycohydrolase MACROD1 OS=Bos
taurus OX=9913 GN=MACROD1 PE=2 SV=1
Length=325
Score = 38.1 bits (87), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 45/161 (28%), Positives = 74/161 (46%), Gaps = 24/161 (15%)
Query 1000 EEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNG 1059
EEP ++ +L + +++ DI K A IVNAAN L GGGV G +++A
Sbjct 140 EEP--KYKKDKQLNEKISLFRGDITKLEVDA----IVNAANSSLLGGGGVDGCIHRAAGP 193
Query 1060 AMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGPNLN---AGEDIQLLKAAYEN 1115
+ +D+ L G + + G+ L AK +H VGP + + L++ Y
Sbjct 194 LL---TDECRTLQN-CETGKAKITCGYRLPAKYVIHTVGPIAHGEPSASQAAELRSCY-- 247
Query 1116 FNSQDILLA--------PLLSAGIFGAKPLQSLQVCVQTVR 1148
+S D+LL P +S G+FG + +V + +R
Sbjct 248 LSSLDLLLEHRLRSAAFPCISTGVFGYPNEAAAEVVLTALR 288
>sp|P18478|POLG_WMV2U Genome polyprotein (Fragment) OS=Watermelon
mosaic virus II (isolate USA) OX=148360 PE=1 SV=3
Length=1017
Score = 38.5 bits (88), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 59/268 (22%), Positives = 109/268 (41%), Gaps = 46/268 (17%)
Query 4823 DYYRYNLPTM---CDIRQLLFVVE-VVDKYFDCYDGGC--INANQVIVNNLDKSAGFPFN 4876
D+++YN P + D VE V+ D C + I +L+ A
Sbjct 291 DFFKYNKPVVLNEVDFNAFEKAVEGVITMMVDFEFAECLFVTDPDEIYGSLNMKAAVGAQ 350
Query 4877 KWGKARLYYDSM-SYEDQDALFAYTKR--NVIPTITQMNLKYAIS-----AKNRART--- 4925
GK + Y+ M S++ + L+ +R N I +LK + N+ RT
Sbjct 351 YKGKKQDYFSGMDSFDKERLLYLSCERLFNGEKGIWNGSLKAELRPIEKVQANKTRTFTA 410
Query 4926 -----VAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
+ G +C N QF+ LK +G +KFYGGW +++++
Sbjct 411 APLDTLLGAKVCVDDFNNQFYSFNLK-------CPWTVGMTKFYGGWDKLMRSLPD---- 459
Query 4981 PHLMGWDYPKCDRAM--PNMLRIMASLVLARKHNTCCNLSHRFY---RLANECAQVLSEM 5035
GW Y D + ++ ++ + VL+ + CC + + L N A+++
Sbjct 460 ----GWTYCHADGSQFDSSLTPLLLNAVLSIR---CCFMEDWWVGREMLENLYAEIVYTP 512
Query 5036 VMC-GGSLYVKPGGTSSGDATTAYANSV 5062
++ G+++ K G +SG +T N++
Sbjct 513 ILAPDGTIFKKFRGNNSGQPSTVVDNTL 540
>sp|Q98TR3|RENT1_TAKRU Putative regulator of nonsense transcripts
1 OS=Takifugu rubripes OX=31033 GN=rent1 PE=3 SV=1
Length=1097
Score = 38.5 bits (88), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 31/131 (24%), Positives = 57/131 (44%), Gaps = 20/131 (15%)
Query 5781 ITHDVSSAINRPQIGVVREFLTR----NPAWRKAVFISPYNSQ-----------NAVASK 5825
I +S +NR + V + TR + I+PY Q ++ +K
Sbjct 738 IASSGTSYLNRTEAANVEKITTRLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTK 797
Query 5826 ILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC-----NVNRFNVAITRAKIGILCIMSDR 5880
+ + +VD+ QG E D++I + H + R NVA+TRAK G++ + + +
Sbjct 798 LYQVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRAKYGVIIVGNPK 857
Query 5881 DLYDKLQFTSL 5891
L + + +L
Sbjct 858 ALSKQPLWNNL 868
>sp|Q985D2|Y7730_RHILO Macro domain-containing protein mll7730
OS=Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 /
MAFF 303099) OX=266835 GN=mll7730 PE=4 SV=1
Length=176
Score = 37.0 bits (84), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 50/170 (29%), Positives = 77/170 (45%), Gaps = 21/170 (12%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
K D + I DI K A IVNAAN L GGGV GA+++A ++ E
Sbjct 3 KALDRIRIHTGDITKLDVDA----IVNAANTLLLGGGGVDGAIHRAAGRELEVECR---M 55
Query 1071 LNGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAG--EDIQLLKAAYEN------FNSQDI 1121
LNG VG + + G+ L A+ +H VGP G + +LL + Y + N
Sbjct 56 LNG-CKVGDAKITKGYKLPARHIIHTVGPVWQGGGKGEAELLASCYRSSLELAAANDCRS 114
Query 1122 LLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDN 1171
+ P +S G++ ++ + V TV + + +KA+ E V+ D
Sbjct 115 VAFPAISTGVYRYPKDEATGIAVGTVS----MVIEEKAMPETVIFCCFDE 160
>sp|Q54I89|RENT1_DICDI Regulator of nonsense transcripts 1 OS=Dictyostelium
discoideum OX=44689 GN=upf1 PE=3 SV=1
Length=1331
Score = 38.5 bits (88), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 54/244 (22%), Positives = 102/244 (42%), Gaps = 43/244 (18%)
Query 5672 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK 5731
++ DE + A+ + ++ + AK + +GD QL P LL K ++ S+ +
Sbjct 703 ILIDESTQASEPEC-LIPLMMGAKQVILVGDHRQL-GP-VLLCKKVVDAGLSQSLFERLI 759
Query 5732 TIG--PDMFLGTCRRCPAEIVDTVSALVYDNKLKA---HKDKSAQCF---------KMFY 5777
++G P+ R P+ + + S Y+ +L + H D+ +Q F+
Sbjct 760 SLGHHPERLTIQYRMHPS-LTEFPSNTSYEGQLVSELSHTDRDSQSKFPWPQPKDPMFFF 818
Query 5778 KGVITHDVSSA----INRPQIGV----VREFLTRNPAWRKAVFISPYNSQNAVASKIL-- 5827
+ ++SS+ IN + + V +FL + I+PY Q A + +
Sbjct 819 NCTGSEEISSSGTSFINTTEASICEKIVTKFLELGSLPGQIGIITPYEGQRAYITSHMQK 878
Query 5828 ----------GLPTQTVDSSQGSEYDYVIFTQTTETAHSC-----NVNRFNVAITRAKIG 5872
+ +VDS QG E DY+I + + + R NVA+TRA+ G
Sbjct 879 SGKLNLELYKSIEVASVDSFQGREKDYIILSCVRSNDYQGIGFLQDPRRLNVALTRARFG 938
Query 5873 ILCI 5876
++ +
Sbjct 939 LIIL 942
>sp|Q5TB80|CE162_HUMAN Centrosomal protein of 162 kDa OS=Homo
sapiens OX=9606 GN=CEP162 PE=1 SV=2
Length=1403
Score = 38.5 bits (88), Expect = 3.4, Method: Composition-based stats.
Identities = 29/103 (28%), Positives = 46/103 (45%), Gaps = 27/103 (26%)
Query 931 EEEDDAECEEEEIDETCEHEYGTEDDYQGLPL---------EFGASAETVRVEEEEEE-- 979
++E + E + EE+ E ++ ED+Y G PL + + +E + V ++EEE
Sbjct 177 DDEHENESKHEELAENYSDDF--EDEYVGAPLTTKDEEMPSKENSKSEKISVPKQEEEKT 234
Query 980 ---------DWLDDTTE-----QSEIEPEPEPTPEEPVNQFTG 1008
D LD E Q +I P+P PE N+ TG
Sbjct 235 GMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTG 277
>sp|E1PL40|YMDB2_PANVC O-acetyl-ADP-ribose deacetylase 2 OS=Pantoea
vagans (strain C9-1) OX=712898 GN=ymdB2 PE=3 SV=1
Length=171
Score = 36.6 bits (83), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 38/131 (29%), Positives = 54/131 (41%), Gaps = 16/131 (12%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
I+N AN L GGGV GA+++A + E G VG + + L A +
Sbjct 19 IINVANSSLLGGGGVDGAIHRAGGPVILAECQAIRSRQGGCKVGEAVITGAGTLPADYVI 78
Query 1094 HVVGPNLNAG---EDIQLLKAAYENF-----NSQDILLAPLLSAGIFG-------AKPLQ 1138
H VGP + G ED QL F + + P +S GI+G A L
Sbjct 79 HTVGPRWSDGRHNEDTQLKSVYLSCFKLVGHHGIKTVSFPNISTGIYGFPKKRAAAIALD 138
Query 1139 SLQVCVQTVRT 1149
++ C+ RT
Sbjct 139 VIKHCIAENRT 149
>sp|O76512|RENT1_CAEEL Regulator of nonsense transcripts 1 OS=Caenorhabditis
elegans OX=6239 GN=smg-2 PE=1 SV=1
Length=1069
Score = 38.5 bits (88), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 29/113 (26%), Positives = 55/113 (49%), Gaps = 16/113 (14%)
Query 5785 VSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL-GLPTQTVDSSQGSEYD 5843
+ + + QIGV+ + +++ ++ ++Q + SK+ + +VD+ QG E D
Sbjct 755 IKAGVQPHQIGVITSY-----EGQRSFIVNYMHTQGTLNSKLYENVEIASVDAFQGREKD 809
Query 5844 YVIFTQTTET-----AHSCNVNRFNVAITRAKIGILC-----IMSDRDLYDKL 5886
Y+I T + R NVAITRAK G++ +++ DL+ +L
Sbjct 810 YIIVTCVRSNDILGIGFLSDPRRLNVAITRAKYGLVLVGNAKVLARHDLWHEL 862
>sp|Q04561|RPOA_PRRSL Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain Lelystad) OX=11049
GN=rep PE=1 SV=3
Length=3855
Score = 38.5 bits (88), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 60/266 (23%), Positives = 101/266 (38%), Gaps = 72/266 (27%)
Query 4886 DSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQ------ 4939
D S + D + A + T+T LK +K + RT+ G + + +R
Sbjct 2696 DVQSIPEIDEMCARAVKENWQTVTPCTLKKQYCSKPKTRTILGTNNFIALAHRSALSGVT 2755
Query 4940 --FHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPN 4997
F +K KS + +G +KF K ++ V L D CDR+ P
Sbjct 2756 QAFMKKAWKS-------PIALGKNKF--------KELHCTVAGRCLEA-DLASCDRSTPA 2799
Query 4998 MLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVM-CGGSL-------YVKPGGT 5049
++R + +L Y LA C + L V+ C L + K GG
Sbjct 2800 IVRWFVANLL--------------YELAG-CEEYLPSYVLNCCHDLVATQDGAFTKRGGL 2844
Query 5050 SSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHE 5109
SSGD T+ +N+V+++ V QH + L ++ +
Sbjct 2845 SSGDPVTSVSNTVYSL-----------------------VIYAQHMVLSALKMGHEIGLK 2881
Query 5110 FVDEFYAY--LRKHFSMMILSDDAVV 5133
F++E + L + M++ SDD V+
Sbjct 2882 FLEEQLKFEDLLEIQPMLVYSDDLVL 2907
>sp|Q5ZKG3|DNA2_CHICK DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Gallus gallus OX=9031 GN=DNA2 PE=2 SV=2
Length=992
Score = 38.1 bits (87), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 79/371 (21%), Positives = 136/371 (37%), Gaps = 93/371 (25%)
Query 5578 YSTLQGPPGTGKSHFAIGLALYYPSA--RIVYTACSHAAVDALCEKALKY----LPIDKC 5631
Y+ + G PGTGK+ L + ++ T+ +H AVD + K K+ L + +
Sbjct 612 YTLIVGMPGTGKTTTICALVRILSACGFSVLLTSFTHTAVDNILLKLAKFKVGFLRLGRA 671
Query 5632 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPE--------TTADIVVFDEISMATNY 5683
++ P KF +V L E TA + + I + +
Sbjct 672 QKVHPD------IRKFTEEEICRSKSIKSVTDLEELYNSQPVVATACMGINHPIFVQKQF 725
Query 5684 DLSVVNARLR------------AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC---R 5728
D +V+ + +K +V +GD QLP L + + + S R
Sbjct 726 DFCIVDEASQISQPICLGPLFCSKRFVLVGDHQQLPP----LVQNSEARDLGMSESLFKR 781
Query 5729 LMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSA 5788
L + + L R ++I+ + LVY+ KL+ +K + ++
Sbjct 782 LEQNQNAVVQLTVQYRMNSKIMSLSNKLVYEGKLECGSEKVS---------------NAT 826
Query 5789 INRPQIGVVR-EFLTRNPAWRKAVF-----------------------ISPYNSQNAVAS 5824
N P + +++ EF + W K V ISPY Q V +
Sbjct 827 ANLPNLKMLKLEFADASKTWLKEVLEPDKPVCFLNTEKAGCRPSDIGIISPYRHQLKVIT 886
Query 5825 KILG------LPTQTVDSSQGSEYDYVIFTQTTET------AHSCNVNRFNVAITRAK-- 5870
++ + T+D QG + +I + + A + R NVAITRAK
Sbjct 887 DLMARLKENRVEVNTIDKYQGRDKSIIIVSFVRNSNDENLGALLKDWRRLNVAITRAKHK 946
Query 5871 -IGILCIMSDR 5880
I + C+ S R
Sbjct 947 LIMVGCVPSLR 957
>sp|E9QAM5|HELZ2_MOUSE 3'-5' exoribonuclease HELZ2 OS=Mus musculus
OX=10090 GN=Helz2 PE=1 SV=1
Length=2947
Score = 38.1 bits (87), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 30/95 (32%), Positives = 45/95 (47%), Gaps = 27/95 (28%)
Query 5813 ISPYNSQNAVASK------ILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVN------ 5860
++PYN+Q A S+ + G+ ++ SQGSE+ YVI + T T +V+
Sbjct 2819 LTPYNAQAAAISRGLMQRGVTGVTVTSITKSQGSEWRYVIVS-TVRTCPRSDVDQRPTKS 2877
Query 5861 -------------RFNVAITRAKIGILCIMSDRDL 5882
+ NVAITRA+ LCI+ D L
Sbjct 2878 WLKKFLGFVVDPHQVNVAITRAQEA-LCIIGDHLL 2911
>sp|P13889|POLN_RUBVT Non-structural polyprotein p200 OS=Rubella
virus (strain Therien) OX=11045 PE=3 SV=5
Length=2116
Score = 38.1 bits (87), Expect = 4.7, Method: Composition-based stats.
Identities = 56/228 (25%), Positives = 84/228 (37%), Gaps = 35/228 (15%)
Query 984 DTTEQSEIEPEPEP------TPEEPVNQFT-GYLKLTDNVAIKCVDIVKEAQSANPMVIV 1036
D +E+E EP T +P + Y + V ++ DI+ V+V
Sbjct 780 DRARDAELEVACEPSGPPTSTRADPDSDIVESYARAAGPVHLRVRDIMDPPPGCK--VVV 837
Query 1037 NAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA-KKCLHV 1095
NAAN L G GV GA+ A+ + P G + GH +H
Sbjct 838 NAANEGLLAGSGVCGAIFANATAALAANC----RRLAPCPTGEAVATPGHGCGYTHIIHA 893
Query 1096 VGPN-------LNAGEDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQV 1142
V P L GE LL+ AY + + PLL AG++G +SL+
Sbjct 894 VAPRRPRDPAALEEGE--ALLERAYRSIVALAAARRWACVACPLLGAGVYGWSAAESLRA 951
Query 1143 CVQTVRTQ------VYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEP 1184
+ RT+ ++I D+A + L R +P EP
Sbjct 952 ALAATRTEPVERVSLHICHPDRATLTHASVLVGAGLAARRVSPPPTEP 999
>sp|A0A339|NDHK_COFAR NAD(P)H-quinone oxidoreductase subunit K,
chloroplastic OS=Coffea arabica OX=13443 GN=ndhK PE=3 SV=1
Length=229
Score = 37.0 bits (84), Expect = 4.9, Method: Compositional matrix adjust.
Identities = 20/98 (20%), Positives = 49/98 (50%), Gaps = 14/98 (14%)
Query 5705 QLPAPRTLL-------TKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL- 5756
Q+P P+ ++ T G + +++V + K I D++L C P ++D ++ L
Sbjct 95 QMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPEAVIDAITKLR 154
Query 5757 ------VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSA 5788
+Y+++++ + +S +CF +K I+ +++
Sbjct 155 KKISREIYEDRIRPQRQRSNRCFTTNHKFHISRSMNTG 192
>sp|Q06502|RPOA_LDVC Replicase polyprotein 1ab OS=Lactate dehydrogenase
elevating virus (strain C) OX=300015 GN=rep PE=3 SV=2
Length=3637
Score = 38.1 bits (87), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 49/204 (24%), Positives = 85/204 (42%), Gaps = 18/204 (9%)
Query 4889 SYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKS- 4947
S+ D DAL + T+T LK +K + RT+ G + + R + +
Sbjct 2527 SHPDIDALCERACKEHWQTVTPCTLKKQYCSKAKTRTILGTNNFVALGLRSALSGVTQGF 2586
Query 4948 IAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVL 5007
+ G+ + +G +KF L T S + D CDR+ P ++R + +L
Sbjct 2587 MRKGIGSPICLGKNKF-----TPLPTKVSG----RCLEADLASCDRSTPAIIRWFTTNLL 2637
Query 5008 ARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQ 5067
+ Y L N C +S M C + K GG SSGD T+ +N+V+++
Sbjct 2638 FELAGPEEWIPS--YVL-NCCHDAVSTMSGC----FDKRGGLSSGDPVTSVSNTVYSLVI 2690
Query 5068 AVTANVNALLSTDGNKIADKYVRN 5091
V + G+K+ ++R+
Sbjct 2691 YAQHMVLSAFRC-GHKVGGLFLRD 2713
>sp|A0MD28|RPOA_PRRSS Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (isolate Pig/United
States/SD 01-08/2001) OX=857306 PE=1 SV=2
Length=3838
Score = 38.1 bits (87), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 57/266 (21%), Positives = 100/266 (38%), Gaps = 72/266 (27%)
Query 4886 DSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQ------ 4939
D S + D + A + T+T LK +K + RT+ G + + +R
Sbjct 2679 DVQSIPEIDEMCARAVKENWQTVTPCTLKKQYCSKPKTRTILGTNNFIALAHRSALSGVT 2738
Query 4940 --FHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPN 4997
F +K KS + +G +KF K ++ V L D CDR+ P
Sbjct 2739 QAFMKKAWKS-------PIALGKNKF--------KELHCTVAGRCLEA-DLASCDRSTPA 2782
Query 4998 MLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLS--------EMVMCGGSLYVKPGGT 5049
++R + +L Y LA C + L ++V + K GG
Sbjct 2783 IVRWFVANLL--------------YELAG-CEEYLPSYVLNCCHDLVATQDGAFTKRGGL 2827
Query 5050 SSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHE 5109
SSGD T+ +N+V+++ + QH + L ++ +
Sbjct 2828 SSGDPVTSVSNTVYSL-----------------------IIYAQHMVLSALKMGHEIGLK 2864
Query 5110 FVDEFYAY--LRKHFSMMILSDDAVV 5133
F++E + L + M++ SDD V+
Sbjct 2865 FLEEQLKFEDLLEIQPMLVYSDDLVL 2890
>sp|Q89330|POLG_ZYMVR Genome polyprotein OS=Zucchini yellow mosaic
virus (strain Reunion Island) OX=117129 PE=3 SV=1
Length=3083
Score = 37.7 bits (86), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 43/192 (22%), Positives = 77/192 (40%), Gaps = 37/192 (19%)
Query 4823 DYYRYNLPTMCDIRQLLFVVEVVDKY------FDCYDGGCINANQVIVNNLDKSAGFPFN 4876
D+++YN P + + +E VD F+ + I + I ++L+ A
Sbjct 2359 DFFKYNKPVIVNQLDHDKFLEAVDGVIRMMCDFEFNECRFITDPEEIYSSLNMKAAIGAQ 2418
Query 4877 KWGKARLYYDSM-SYEDQDALFAYTKR--NVIPTITQMNLKYAIS-----AKNRART--- 4925
GK + Y++ + +++ + LF +R N + +LK + N+ RT
Sbjct 2419 YRGKKKEYFEGLDNFDMERLLFQSCERLFNGYKGLWNGSLKAELRPLEKVQANKTRTFTA 2478
Query 4926 -----VAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
+ G +C N +F+ K LK +G SKFYGGW +++ +
Sbjct 2479 APIDTLLGAKVCVDDFNNEFYSKNLK-------CPWTVGMSKFYGGWDKLMRALPD---- 2527
Query 4981 PHLMGWDYPKCD 4992
GW Y D
Sbjct 2528 ----GWLYCHAD 2535
>sp|A1Z1Q3|MACD2_HUMAN ADP-ribose glycohydrolase MACROD2 OS=Homo
sapiens OX=9606 GN=MACROD2 PE=1 SV=2
Length=425
Score = 37.0 bits (84), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 39/112 (35%), Positives = 55/112 (49%), Gaps = 18/112 (16%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKC 1092
IVNAAN L GGGV G +++A + E + LNG G + + G++L AK
Sbjct 86 AIVNAANASLLGGGGVDGCIHRAAGPCLLAECRN---LNG-CDTGHAKITCGYDLPAKYV 141
Query 1093 LHVVGP------NLNAGEDI-----QLLKAAYENFNSQDILLAPLLSAGIFG 1133
+H VGP N + ED+ LK EN N + + P +S GI+G
Sbjct 142 IHTVGPIARGHINGSHKEDLANCYKSSLKLVKEN-NIRSVAF-PCISTGIYG 191
>sp|Q3ZX83|TIG_DEHMC Trigger factor OS=Dehalococcoides mccartyi
(strain CBDB1) OX=255470 GN=tig PE=3 SV=1
Length=447
Score = 37.0 bits (84), Expect = 8.6, Method: Composition-based stats.
Identities = 27/115 (23%), Positives = 57/115 (50%), Gaps = 9/115 (8%)
Query 3903 DINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAY----EQAVANGDSEVVLKKLK 3958
+++++ E+ L + EF ++ S Q+ Y EQ VA S +VL KL
Sbjct 308 ELDQIIEQQLQRLQSNVKSPEEFRAMLSQMTPEDMQQRYRPLAEQRVA---SSLVLGKLA 364
Query 3959 KSLNVAKSEFDRDAAMQRKLEKMADQAMTQ--MYKQARSEDKRAKVTSAMQTMLF 4011
+ N+ ++ + DA +++ + D+ + +Y Q+ + D+ ++ +A +TM F
Sbjct 365 TTENLVPNDEEVDAEIEKLITDAGDKKEEEKALYNQSETRDRLIQLLTARKTMAF 419
>sp|O60306|AQR_HUMAN RNA helicase aquarius OS=Homo sapiens OX=9606
GN=AQR PE=1 SV=4
Length=1485
Score = 37.0 bits (84), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 31/102 (30%), Positives = 50/102 (49%), Gaps = 9/102 (9%)
Query 5537 SAPTLVPQEHYVRITGLYP---TLNISDEFSSNVANYQKVGMQKYSTLQ-GPPGTGKSHF 5592
A TL+ + H + G YP + +F+ + GMQ T+ GPPGTGK+
Sbjct 773 EAKTLIVEPHVIPNRGPYPYNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDV 832
Query 5593 AIGLA--LY--YPSARIVYTACSHAAVDALCEKALKYLPIDK 5630
A+ + +Y +P R + S+ A++ L EK + L ID+
Sbjct 833 AVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIMA-LDIDE 873
>sp|Q83017|RPOA_LDVP Replicase polyprotein 1ab OS=Lactate dehydrogenase
elevating virus (strain Plagemann) OX=300016 GN=rep
PE=1 SV=2
Length=3616
Score = 37.0 bits (84), Expect = 10.0, Method: Compositional matrix adjust.
Identities = 57/247 (23%), Positives = 100/247 (40%), Gaps = 26/247 (11%)
Query 4889 SYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKS- 4947
S+ D DAL T+T LK +K++ RT+ G + + R + +
Sbjct 2506 SHPDIDALCKRACEEHWQTVTPCTLKKQYCSKSKTRTILGTNNFVALGLRSALSGVTQGF 2565
Query 4948 IAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVL 5007
+ G + +G +KF T + D CDR+ P ++R + +L
Sbjct 2566 MRKGIGTPICLGKNKF---------TPLPVRIGGRCLEADLASCDRSTPAIIRWFTTNLL 2616
Query 5008 ARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQ 5067
+ Y L N C V+S M C + K GG SSGD T+ +N+V+++
Sbjct 2617 FELAGAEEWIPS--YVL-NCCHDVVSTMSGC----FDKRGGLSSGDPVTSISNTVYSLII 2669
Query 5068 AVTANVNALLSTDGNKIADKYVRNL--QHRLYE----CLYRNRDVDHEFVDEF--YAYLR 5119
V + G+KI ++++ +L+E +Y + V + DE Y +
Sbjct 2670 YAQHMVLSAFRC-GHKIGGLFLQDSLEMEQLFELQPLLVYSDDVVFYNESDELPNYHFFV 2728
Query 5120 KHFSMMI 5126
H +M+
Sbjct 2729 DHLDLML 2735
Lambda K H a alpha
0.321 0.136 0.413 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 870231075712
Results from round 2
Query= sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute res... 10842 0.0
sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus... 10786 0.0
sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus... 10699 0.0
sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus... 10697 0.0
sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute re... 10430 0.0
sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus... 9110 0.0
sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus... 8614 0.0
sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus... 8605 0.0
sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus... 8558 0.0
sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East res... 8040 0.0
sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavir... 7844 0.0
sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavir... 7839 0.0
sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavi... 7832 0.0
sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavi... 7770 0.0
sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavi... 7769 0.0
sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavi... 7759 0.0
sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavir... 7725 0.0
sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavir... 7720 0.0
sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavir... 7665 0.0
sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavir... 7647 0.0
sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavir... 7641 0.0
sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus... 6828 0.0
sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemi... 6818 0.0
sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavir... 6803 0.0
sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavir... 6769 0.0
sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmi... 6757 0.0
sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavir... 6696 0.0
sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious... 6409 0.0
sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious... 6360 0.0
sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectiou... 6359 0.0
sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respi... 6306 0.0
sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus R... 6272 0.0
sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus H... 6191 0.0
sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus 2... 6179 0.0
sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute resp... 5962 0.0
sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus H... 4843 0.0
sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus H... 4429 0.0
sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus 1... 4422 0.0
sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus H... 4372 0.0
sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus... 3797 0.0
sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respi... 3792 0.0
sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus... 3615 0.0
sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronaviru... 3608 0.0
sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronaviru... 3601 0.0
sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronaviru... 3563 0.0
sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronaviru... 3563 0.0
sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus... 3541 0.0
sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus... 3538 0.0
sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus... 3486 0.0
sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus... 3482 0.0
sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus... 3475 0.0
sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus... 2616 0.0
sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus... 2608 0.0
sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus 5... 2590 0.0
sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic ... 2568 0.0
sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmiss... 2519 0.0
sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious b... 2509 0.0
sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious ... 2487 0.0
sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious b... 2487 0.0
sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porc... 769 0.0
sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian... 634 0.0
sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11... 620 1e-175
sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus 1 OX... 612 2e-173
sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream vir... 608 3e-172
sp|Q9WQ77|R1AB_CVRSD Replicase polyprotein 1ab (Fragment) OS=Rat ... 511 2e-163
sp|Q9WQ76|R1AB_CVTMI Replicase polyprotein 1ab (Fragment) OS=Turk... 480 8e-153
sp|P36697|R1AB_CVCAI Replicase polyprotein 1ab (Fragment) OS=Cani... 268 1e-80
sp|Q04158|R1AB_CVPR8 Replicase polyprotein 1ab (Fragment) OS=Porc... 212 6e-62
sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 OS=Arabidopsis th... 236 2e-61
sp|P38859|DNA2_YEAST DNA replication ATP-dependent helicase/nucle... 196 3e-48
sp|B6SFA4|MAA3_ARATH Probable helicase MAGATAMA 3 OS=Arabidopsis ... 189 3e-47
sp|B5F961|YMDB_SALA4 O-acetyl-ADP-ribose deacetylase OS=Salmonell... 160 5e-43
sp|B4T2X8|YMDB_SALNS O-acetyl-ADP-ribose deacetylase OS=Salmonell... 160 6e-43
sp|P67341|YMDB_SALTY O-acetyl-ADP-ribose deacetylase OS=Salmonell... 160 8e-43
sp|P67342|YMDB_SALTI O-acetyl-ADP-ribose deacetylase OS=Salmonell... 160 8e-43
sp|A7MG20|YMDB_CROS8 O-acetyl-ADP-ribose deacetylase OS=Cronobact... 159 9e-43
sp|B5RBF3|YMDB_SALG2 O-acetyl-ADP-ribose deacetylase OS=Salmonell... 158 2e-42
sp|D5CE05|YMDB_ENTCC O-acetyl-ADP-ribose deacetylase OS=Enterobac... 158 2e-42
sp|C9Y0V8|YMDB_CROTZ O-acetyl-ADP-ribose deacetylase OS=Cronobact... 158 3e-42
sp|A4W960|YMDB_ENT38 O-acetyl-ADP-ribose deacetylase OS=Enterobac... 158 3e-42
sp|P0A8D6|YMDB_ECOLI O-acetyl-ADP-ribose deacetylase OS=Escherich... 158 3e-42
sp|P0A8D7|YMDB_ECOL6 O-acetyl-ADP-ribose deacetylase OS=Escherich... 158 3e-42
sp|P0A8D8|YMDB_ECO57 O-acetyl-ADP-ribose deacetylase OS=Escherich... 158 3e-42
sp|B7LT90|YMDB_ESCF3 O-acetyl-ADP-ribose deacetylase OS=Escherich... 157 5e-42
sp|Q0T5Z6|YMDB_SHIF8 O-acetyl-ADP-ribose deacetylase OS=Shigella ... 156 1e-41
sp|D2TT52|YMDB_CITRI O-acetyl-ADP-ribose deacetylase OS=Citrobact... 155 2e-41
sp|A8AI35|YMDB_CITK8 O-acetyl-ADP-ribose deacetylase OS=Citrobact... 154 5e-41
sp|D3RKJ0|YMDB_KLEVT O-acetyl-ADP-ribose deacetylase OS=Klebsiell... 154 9e-41
sp|B5XXK9|YMDB_KLEP3 O-acetyl-ADP-ribose deacetylase OS=Klebsiell... 154 9e-41
sp|Q92355|SEN1_SCHPO Helicase sen1 OS=Schizosaccharomyces pombe (... 171 2e-40
sp|Q32E73|YMDB_SHIDS O-acetyl-ADP-ribose deacetylase OS=Shigella ... 152 4e-40
sp|P0C6F3|R1A_BEV Replicase polyprotein 1a OS=Berne virus OX=1115... 153 8e-35
sp|Q4J9D2|Y1252_SULAC Uncharacterized protein Saci_1252 OS=Sulfol... 136 1e-34
sp|Q8KAE4|Y2219_CHLTE Macro domain-containing protein CT2219 OS=C... 135 2e-34
sp|Q96XY5|Y2383_SULTO Uncharacterized protein STK_23830 OS=Sulfur... 135 2e-34
sp|Q8ZXT3|Y1111_PYRAE Uncharacterized protein PAE1111 OS=Pyrobacu... 134 1e-33
sp|Q97UU4|Y2899_SACS2 Uncharacterized protein SSO2899 OS=Saccharo... 133 1e-33
sp|Q9WYX8|Y508_THEMA Uncharacterized protein TM_0508 OS=Thermotog... 143 3e-33
sp|P0C6F4|R1A_BRV1 Replicase polyprotein 1a OS=Breda virus 1 OX=3... 144 4e-32
sp|Q8RB30|Y995_CALS4 Macro domain-containing protein TTE0995 OS=C... 129 5e-32
sp|Q87JZ5|Y4103_VIBPA Macro domain-containing protein VPA0103 OS=... 122 7e-30
sp|Q2EMV9|PAR14_MOUSE Protein mono-ADP-ribosyltransferase PARP14 ... 134 3e-29
sp|Q8IXQ6|PARP9_HUMAN Protein mono-ADP-ribosyltransferase PARP9 O... 132 6e-29
sp|Q8CAS9|PARP9_MOUSE Protein mono-ADP-ribosyltransferase PARP9 O... 130 2e-28
sp|Q8RHQ2|Y1951_FUSNN Uncharacterized protein FN1951 OS=Fusobacte... 117 4e-28
sp|Q460N5|PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14 ... 129 1e-27
sp|P36328|POLN_EEVVP Polyprotein P1234 OS=Venezuelan equine encep... 105 1e-20
sp|P36327|POLN_EEVV3 Polyprotein P1234 OS=Venezuelan equine encep... 105 2e-20
sp|P27282|POLN_EEVVT Polyprotein P1234 OS=Venezuelan equine encep... 105 2e-20
sp|Q8V294|POLN_EEVVC Polyprotein P1234 OS=Venezuelan equine encep... 105 2e-20
Sequences not found previously or not previously below threshold:
sp|E1SDF1|YMDB1_PANVC O-acetyl-ADP-ribose deacetylase 1 OS=Pantoe... 140 6e-36
sp|Q8EYT0|Y4133_LEPIN Macro domain-containing protein LA_4133 OS=... 139 1e-35
sp|Q72M93|Y3295_LEPIC Macro domain-containing protein LIC_13295 O... 139 1e-35
sp|Q5ZKG3|DNA2_CHICK DNA replication ATP-dependent helicase/nucle... 141 1e-31
sp|Q8Q0F9|Y177_METMA Macro domain-containing protein MM_0177 OS=M... 128 1e-31
sp|O94387|YGSA_SCHPO Uncharacterized ATP-dependent helicase C29A1... 142 1e-31
sp|E1PL40|YMDB2_PANVC O-acetyl-ADP-ribose deacetylase 2 OS=Pantoe... 126 2e-31
sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 homolog... 140 3e-31
sp|Q09820|RENT1_SCHPO ATP-dependent helicase upf1 OS=Schizosaccha... 139 4e-31
sp|E1BMP7|DNA2_BOVIN DNA replication ATP-dependent helicase/nucle... 139 7e-31
sp|Q9VYS3|RENT1_DROME Regulator of nonsense transcripts 1 homolog... 139 8e-31
sp|Q86AS0|Y4399_DICDI Probable helicase DDB_G0274399 OS=Dictyoste... 137 2e-30
sp|Q00416|SEN1_YEAST Helicase SEN1 OS=Saccharomyces cerevisiae (s... 138 3e-30
sp|P23249|MOV10_MOUSE Putative helicase MOV-10 OS=Mus musculus OX... 136 5e-30
sp|P30771|RENT1_YEAST ATP-dependent helicase NAM7 OS=Saccharomyce... 134 1e-29
sp|P51530|DNA2_HUMAN DNA replication ATP-dependent helicase/nucle... 135 1e-29
sp|Q1LXK4|M10B1_DANRE Putative helicase mov-10-B.1 OS=Danio rerio... 133 3e-29
sp|Q9HCE1|MOV10_HUMAN Helicase MOV-10 OS=Homo sapiens OX=9606 GN=... 133 4e-29
sp|D3ZG52|DNA2_RAT DNA replication ATP-dependent helicase/nucleas... 133 4e-29
sp|Q6ZQJ5|DNA2_MOUSE DNA replication ATP-dependent helicase/nucle... 133 4e-29
sp|Q8PHB6|Y3343_XANAC Macro domain-containing protein XAC3343 OS=... 120 6e-29
sp|Q8Y2K1|Y334_RALN1 Macro domain-containing protein RSc0334 OS=R... 120 6e-29
sp|Q7MTZ7|MACRO_PORGI Macro domain-containing protein PG1779 OS=P... 119 6e-29
sp|Q8P5Z8|Y3184_XANCP Macro domain-containing protein XCC3184 OS=... 119 8e-29
sp|Q926Y8|Y2902_LISIN Macro domain-containing protein lin2902 OS=... 119 9e-29
sp|Q71W03|Y2748_LISMF Macro domain-containing protein LMOf2365_27... 119 1e-28
sp|Q8Y3S3|Y2759_LISMO Macro domain-containing protein lmo2759 OS=... 119 1e-28
sp|Q9HXU7|Y3693_PSEAE Macro domain-containing protein PA3693 OS=P... 119 1e-28
sp|Q9BXT6|M10L1_HUMAN RNA helicase Mov10l1 OS=Homo sapiens OX=960... 131 2e-28
sp|Q1LXK5|M10B2_DANRE Putative helicase mov-10-B.2 OS=Danio rerio... 131 2e-28
sp|Q9FJR0|RENT1_ARATH Regulator of nonsense transcripts 1 homolog... 131 2e-28
sp|Q93SX7|Y189_ACISE Macro domain-containing protein OS=Acinetoba... 118 3e-28
sp|O76512|RENT1_CAEEL Regulator of nonsense transcripts 1 OS=Caen... 130 3e-28
sp|Q8TQD0|Y1614_METAC Macro domain-containing protein MA_1614 OS=... 118 4e-28
sp|Q0V8H6|MOV10_BOVIN Putative helicase MOV-10 OS=Bos taurus OX=9... 130 4e-28
sp|Q5ZKD7|MOV10_CHICK Putative helicase MOV-10 OS=Gallus gallus O... 129 4e-28
sp|Q8QHA5|DNA2_XENLA DNA replication ATP-dependent helicase/nucle... 129 8e-28
sp|Q54I89|RENT1_DICDI Regulator of nonsense transcripts 1 OS=Dict... 129 9e-28
sp|Q88SK6|Y3408_LACPL Macro domain-containing protein lp_3408 OS=... 116 1e-27
sp|Q985D2|Y7730_RHILO Macro domain-containing protein mll7730 OS=... 115 3e-27
sp|A0A1P8ASY1|JHS1_ARATH DNA replication ATP-dependent helicase/n... 127 3e-27
sp|Q9EPU0|RENT1_MOUSE Regulator of nonsense transcripts 1 OS=Mus ... 127 3e-27
sp|Q92900|RENT1_HUMAN Regulator of nonsense transcripts 1 OS=Homo... 127 3e-27
sp|Q9KHE2|Y189_STRGR Macro domain-containing protein in non 5'reg... 114 4e-27
sp|F1RCY6|RENT1_DANRE Regulator of nonsense transcripts 1 OS=Dani... 126 5e-27
sp|Q9ZBG3|Y6450_STRCO Macro domain-containing protein SCO6450 OS=... 114 5e-27
sp|A2AKX3|SETX_MOUSE Probable helicase senataxin OS=Mus musculus ... 126 8e-27
sp|Q97AU0|Y719_THEVO Uncharacterized protein TV0719 OS=Thermoplas... 113 2e-26
sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens ... 125 2e-26
sp|O94247|HCS1_SCHPO DNA polymerase alpha-associated DNA helicase... 122 4e-26
sp|Q6PAV8|MACD2_XENLA ADP-ribose glycohydrolase MACROD2 OS=Xenopu... 118 5e-26
sp|Q9EYI6|Y189_STRNO Macro domain-containing protein in sno 5'reg... 112 5e-26
sp|Q9RS39|Y2288_DEIRA Macro domain-containing protein DR_2288 OS=... 111 5e-26
sp|Q57568|Y104_METJA Uncharacterized ATP-dependent helicase MJ010... 121 8e-26
sp|Q99MV5|M10L1_MOUSE RNA helicase Mov10l1 OS=Mus musculus OX=100... 121 2e-25
sp|Q44020|YGB2_CUPNE Macro domain-containing protein in gbd 3'reg... 109 2e-25
sp|Q3UYG8|MACD2_MOUSE ADP-ribose glycohydrolase MACROD2 OS=Mus mu... 117 2e-25
sp|Q0VGT4|ZGRF1_MOUSE 5'-3' DNA helicase ZGRF1 OS=Mus musculus OX... 119 1e-24
sp|A1Z1Q3|MACD2_HUMAN ADP-ribose glycohydrolase MACROD2 OS=Homo s... 113 2e-24
sp|P34243|HCS1_YEAST DNA polymerase alpha-associated DNA helicase... 115 4e-24
sp|Q9HJ67|Y1105_THEAC Uncharacterized protein Ta1105 OS=Thermopla... 106 5e-24
sp|Q9BQ69|MACD1_HUMAN ADP-ribose glycohydrolase MACROD1 OS=Homo s... 109 1e-23
sp|Q2KHU5|MACD1_BOVIN ADP-ribose glycohydrolase MACROD1 OS=Bos ta... 108 2e-23
sp|Q8K4G6|MACD1_RAT ADP-ribose glycohydrolase MACROD1 (Fragment) ... 107 2e-23
sp|Q86YA3|ZGRF1_HUMAN 5'-3' DNA helicase ZGRF1 OS=Homo sapiens OX... 114 5e-23
sp|Q922B1|MACD1_MOUSE ADP-ribose glycohydrolase MACROD1 OS=Mus mu... 106 1e-22
sp|P38935|SMBP2_HUMAN DNA-binding protein SMUBP-2 OS=Homo sapiens... 108 2e-21
sp|Q9URU2|DNA2_SCHPO DNA replication ATP-dependent helicase/nucle... 108 2e-21
sp|P32644|ECM32_YEAST Putative ATP-dependent RNA helicase ECM32 O... 106 6e-21
sp|Q98TR3|RENT1_TAKRU Putative regulator of nonsense transcripts ... 106 9e-21
sp|Q6J5K9|ARMI_DROME Probable RNA helicase armi OS=Drosophila mel... 105 1e-20
sp|Q9WJC7|POLN_EEVVM Polyprotein P1234 OS=Venezuelan equine encep... 105 2e-20
sp|Q60560|SMBP2_MESAU DNA-binding protein SMUBP-2 OS=Mesocricetus... 104 3e-20
sp|E9QAM5|HELZ2_MOUSE 3'-5' exoribonuclease HELZ2 OS=Mus musculus... 102 2e-19
sp|Q008X5|R1A_WBV24 Replicase polyprotein 1a OS=White bream virus... 102 2e-19
sp|O59182|Y1513_PYRHO Uncharacterized protein PH1513 OS=Pyrococcu... 92.8 3e-19
sp|Q9EQN5|SMBP2_RAT DNA-binding protein SMUBP-2 OS=Rattus norvegi... 99.0 1e-18
sp|Q9V0Y3|Y656_PYRAB Uncharacterized protein PYRAB06560 OS=Pyroco... 89.0 5e-18
sp|O28751|Y1521_ARCFU ADP-ribose glycohydrolase AF_1521 OS=Archae... 88.2 1e-17
sp|Q09449|YQ12_CAEEL Uncharacterized ATP-dependent helicase C05C1... 95.9 1e-17
sp|P40694|SMBP2_MOUSE DNA-binding protein SMUBP-2 OS=Mus musculus... 95.1 2e-17
sp|Q9BYK8|HELZ2_HUMAN 3'-5' exoribonuclease HELZ2 OS=Homo sapiens... 93.6 8e-17
sp|Q6NYU2|HELZ_DANRE Probable helicase with zinc finger domain OS... 90.1 9e-16
sp|E9P860|ZNFX1_CAEEL NFX1-type zinc finger-containing protein 1 ... 86.7 1e-14
sp|Q8U0P9|Y1536_PYRFU Uncharacterized protein PF1536 OS=Pyrococcu... 78.9 2e-14
sp|O67112|Y987_AQUAE Uncharacterized protein aq_987 OS=Aquifex ae... 77.4 4e-14
sp|Q8R151|ZNFX1_MOUSE NFX1-type zinc finger-containing protein 1 ... 84.0 7e-14
sp|Q9P2E3|ZNFX1_HUMAN NFX1-type zinc finger-containing protein 1 ... 83.6 7e-14
sp|P13889|POLN_RUBVT Non-structural polyprotein p200 OS=Rubella v... 83.6 8e-14
sp|Q7TZB9|Y1934_MYCBO Uncharacterized protein Mb1934c OS=Mycobact... 80.5 8e-14
sp|P9WK29|Y1899_MYCTU Uncharacterized protein Rv1899c OS=Mycobact... 80.5 8e-14
sp|P9WK28|Y1899_MYCTO Uncharacterized protein MT1950 OS=Mycobacte... 80.5 1e-13
sp|Q5JER1|Y1890_THEKO Uncharacterized protein TK1890 OS=Thermococ... 76.3 1e-13
sp|Q8BCR0|POLN_RUBVN Non-structural polyprotein p200 OS=Rubella v... 82.8 1e-13
sp|P27283|POLN_SINDO Polyprotein P1234 OS=Sindbis virus subtype O... 82.4 2e-13
sp|P13896|POLN_WEEV Polyprotein P1234 OS=Western equine encephali... 82.0 2e-13
sp|P03317|POLN_SINDV Polyprotein P1234 OS=Sindbis virus OX=11034 ... 81.6 3e-13
sp|Q4QXJ8|POLN_EEEVF Polyprotein P1234 OS=Eastern equine encephal... 81.6 3e-13
sp|Q02874|H2AY_RAT Core histone macro-H2A.1 OS=Rattus norvegicus ... 78.6 4e-13
sp|Q9QZQ8|H2AY_MOUSE Core histone macro-H2A.1 OS=Mus musculus OX=... 78.2 6e-13
sp|Q8NYB7|ADPRH_STAAW Protein-ADP-ribose hydrolase OS=Staphylococ... 76.3 7e-13
sp|Q6GCE6|ADPRH_STAAS Protein-ADP-ribose hydrolase OS=Staphylococ... 76.3 7e-13
sp|Q5HIW9|ADPRH_STAAC Protein-ADP-ribose hydrolase OS=Staphylococ... 76.3 8e-13
sp|Q6X2U2|POLN_RUBVC Non-structural polyprotein p200 OS=Rubella v... 80.1 9e-13
sp|O75367|H2AY_HUMAN Core histone macro-H2A.1 OS=Homo sapiens OX=... 77.4 9e-13
sp|Q86924|POLN_AURAV Polyprotein P1234 OS=Aura virus OX=44158 PE=... 80.1 1e-12
sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reprodu... 80.1 1e-12
sp|O40955|POLN_RUBVR Non-structural polyprotein p200 OS=Rubella v... 79.7 1e-12
sp|A7T167|GDAP2_NEMVE Protein GDAP2 homolog OS=Nematostella vecte... 78.6 1e-12
sp|Q6X2U4|POLN_RUBVB Non-structural polyprotein p200 OS=Rubella v... 79.7 1e-12
sp|Q5XXP4|POLN_CHIK3 Polyprotein P1234 OS=Chikungunya virus (stra... 79.3 1e-12
sp|Q8P0X2|ADPRH_STRP8 Protein-ADP-ribose hydrolase OS=Streptococc... 75.5 1e-12
sp|Q5XC09|ADPRH_STRP6 Protein-ADP-ribose hydrolase OS=Streptococc... 75.1 2e-12
sp|O93327|H2AY_CHICK Core histone macro-H2A.1 OS=Gallus gallus OX... 77.0 2e-12
sp|P0DN70|ADPRH_STRPG Protein-ADP-ribose hydrolase OS=Streptococc... 75.1 2e-12
sp|P0DC29|ADPRH_STRPQ Protein-ADP-ribose hydrolase OS=Streptococc... 75.1 2e-12
sp|P0DC28|ADPRH_STRP3 Protein-ADP-ribose hydrolase OS=Streptococc... 75.1 2e-12
sp|A6YQT5|RPOA_PRRSV Replicase polyprotein 1ab OS=Porcine reprodu... 78.9 2e-12
sp|Q8JUX6|POLN_CHIKS Polyprotein P1234 OS=Chikungunya virus (stra... 78.9 2e-12
sp|Q6DFV5|HELZ_MOUSE Probable helicase with zinc finger domain OS... 78.9 2e-12
sp|Q99ZI6|ADPRH_STRP1 Protein-ADP-ribose hydrolase OS=Streptococc... 74.7 2e-12
sp|P67344|ADPRH_STAAN Protein-ADP-ribose hydrolase OS=Staphylococ... 74.3 3e-12
sp|P67343|ADPRH_STAAM Protein-ADP-ribose hydrolase OS=Staphylococ... 74.3 3e-12
sp|Q306W6|POLN_EEEV1 Polyprotein P1234 OS=Eastern equine encephal... 78.6 3e-12
sp|P42694|HELZ_HUMAN Probable helicase with zinc finger domain OS... 77.8 4e-12
sp|Q6GJZ1|ADPRH_STAAR Protein-ADP-ribose hydrolase OS=Staphylococ... 73.9 5e-12
sp|Q306W8|POLN_EEEV8 Polyprotein P1234 OS=Eastern equine encephal... 77.0 7e-12
sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reprodu... 77.0 8e-12
sp|O90368|POLN_ONNVS Polyprotein P1234 OS=O'nyong-nyong virus (st... 77.0 9e-12
sp|O74465|HRR1_SCHPO Helicase required for RNAi-mediated heteroch... 76.3 1e-11
sp|O90370|POLN_ONNVI Polyprotein P1234 OS=O'nyong-nyong virus (st... 76.6 1e-11
sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reprodu... 76.6 1e-11
sp|Q93RG0|ADPRH_TREMD Protein-ADP-ribose hydrolase OS=Treponema m... 72.4 1e-11
sp|Q99IE5|POLN_RUBVV Non-structural polyprotein p200 OS=Rubella v... 76.3 1e-11
sp|Q99IE7|POLN_RUBVO Non-structural polyprotein p200 OS=Rubella v... 76.3 1e-11
sp|P13886|POLN_ONNVG Polyprotein P1234 OS=O'nyong-nyong virus (st... 75.9 2e-11
sp|F6QXW0|DNA2_XENTR DNA replication ATP-dependent helicase/nucle... 75.1 2e-11
sp|Q9J6K9|POLN_RUBVD Non-structural polyprotein p200 OS=Rubella v... 75.1 3e-11
sp|P87515|POLN_BFV Polyprotein P1234 OS=Barmah forest virus OX=11... 75.1 3e-11
sp|P13888|POLN_RRVT Polyprotein nsP1234 (Fragment) OS=Ross river ... 74.3 5e-11
sp|P13887|POLN_RRVN Polyprotein P1234 OS=Ross river virus (strain... 73.6 9e-11
sp|Q8CFQ3|AQR_MOUSE RNA helicase aquarius OS=Mus musculus OX=1009... 73.2 1e-10
sp|O60306|AQR_HUMAN RNA helicase aquarius OS=Homo sapiens OX=9606... 73.2 1e-10
sp|Q6QLN1|POLN_AHEV Non-structural polyprotein pORF1 OS=Avian hep... 72.8 1e-10
sp|Q8QZ73|POLN_MAYAB Polyprotein P1234 OS=Mayaro virus (strain Br... 72.0 3e-10
sp|Q9YBE9|Y1648_AERPE Uncharacterized protein APE_1648.1 OS=Aerop... 66.6 3e-10
sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhag... 71.6 4e-10
sp|Q8QL53|POLN_SLDV Polyprotein P1234 OS=Sleeping disease virus O... 71.2 5e-10
sp|Q86500|POLN_RUBVM Non-structural polyprotein p200 OS=Rubella v... 70.9 5e-10
sp|Q8JJX1|POLN_SPDV Polyprotein P1234 OS=Salmon pancreas disease ... 70.1 9e-10
sp|Q9JGL0|POLN_SAGV Polyprotein P1234 OS=Sagiyama virus OX=59303 ... 69.7 1e-09
sp|Q5Y389|POLN_GETV Polyprotein P1234 OS=Getah virus OX=59300 PE=... 69.7 1e-09
sp|A0MD28|RPOA_PRRSS Replicase polyprotein 1ab OS=Porcine reprodu... 68.9 2e-09
sp|Q06502|RPOA_LDVC Replicase polyprotein 1ab OS=Lactate dehydrog... 68.9 2e-09
sp|Q04561|RPOA_PRRSL Replicase polyprotein 1ab OS=Porcine reprodu... 68.5 3e-09
sp|Q5XGM5|GDAP2_XENLA Ganglioside-induced differentiation-associa... 66.2 7e-09
sp|Q83017|RPOA_LDVP Replicase polyprotein 1ab OS=Lactate dehydrog... 67.0 1e-08
sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteriti... 66.6 1e-08
sp|Q2KIX2|GDAP2_BOVIN Ganglioside-induced differentiation-associa... 64.7 2e-08
sp|Q460N3|PAR15_HUMAN Protein mono-ADP-ribosyltransferase PARP15 ... 63.9 4e-08
sp|P47386|Y140_MYCGE Uncharacterized ATP-dependent helicase MG140... 64.3 5e-08
sp|Q66HX8|GDAP2_DANRE Ganglioside-induced differentiation-associa... 63.2 7e-08
sp|Q66H63|GDAP2_RAT Ganglioside-induced differentiation-associate... 63.2 7e-08
sp|Q9NXN4|GDAP2_HUMAN Ganglioside-induced differentiation-associa... 62.8 8e-08
sp|Q9DBL2|GDAP2_MOUSE Ganglioside-induced differentiation-associa... 62.0 2e-07
sp|Q5CZL1|GDAP2_XENTR Ganglioside-induced differentiation-associa... 61.6 2e-07
sp|Q4R678|GDAP2_MACFA Ganglioside-induced differentiation-associa... 60.8 3e-07
sp|P75033|Y153_MYCPN Uncharacterized ATP-dependent helicase MG140... 61.6 3e-07
sp|Q9P0M6|H2AW_HUMAN Core histone macro-H2A.2 OS=Homo sapiens OX=... 60.5 3e-07
sp|Q8CCK0|H2AW_MOUSE Core histone macro-H2A.2 OS=Mus musculus OX=... 58.5 1e-06
sp|P18479|POLG_ZYMVC Genome polyprotein OS=Zucchini yellow mosaic... 58.5 3e-06
sp|Q9YLR1|POLN_HEVUS Non-structural polyprotein pORF1 OS=Hepatiti... 57.8 5e-06
sp|Q7JUR6|GDAP2_DROME Protein GDAP2 homolog OS=Drosophila melanog... 55.4 2e-05
sp|Q6J8G2|POLN_HEVMG Non-structural polyprotein pORF1 OS=Hepatiti... 55.4 2e-05
sp|Q81862|POLN_HEVCH Non-structural polyprotein pORF1 OS=Hepatiti... 55.4 3e-05
sp|Q03495|POLN_HEVME Non-structural polyprotein pORF1 OS=Hepatiti... 55.1 3e-05
sp|P18478|POLG_WMV2U Genome polyprotein (Fragment) OS=Watermelon ... 54.3 5e-05
sp|P33424|POLN_HEVPA Non-structural polyprotein pORF1 OS=Hepatiti... 54.3 5e-05
sp|P29324|POLN_HEVBU Non-structural polyprotein pORF1 OS=Hepatiti... 54.3 5e-05
sp|Q292F9|GDAP2_DROPS Protein GDAP2 homolog OS=Drosophila pseudoo... 53.9 5e-05
sp|Q9M041|BH140_ARATH Transcription factor bHLH140 OS=Arabidopsis... 54.3 5e-05
sp|Q89330|POLG_ZYMVR Genome polyprotein OS=Zucchini yellow mosaic... 53.9 8e-05
sp|O36979|POLG_ZYMVS Genome polyprotein OS=Zucchini yellow mosaic... 53.5 1e-04
sp|Q9YRB3|RDRP_NCBVS Methyltransferase/helicase/RNA-directed RNA ... 53.1 1e-04
sp|P89659|RDRP_ORSVC Replicase large subunit OS=Odontoglossum rin... 52.8 1e-04
sp|A0A0D2UG83|H2AY_CAPO3 Histone macroH2A1.1 OS=Capsaspora owczar... 51.2 2e-04
sp|Q67724|RDRP_HASV Methyltransferase/helicase/RNA-directed RNA p... 52.0 3e-04
sp|Q9WC28|POLN_HEVHY Non-structural polyprotein pORF1 OS=Hepatiti... 51.6 4e-04
sp|Q01901|POLG_PRSVH Genome polyprotein OS=Papaya ringspot virus ... 51.6 4e-04
sp|Q9J942|RDRP_TRVPP Replicase large subunit OS=Tobacco rattle vi... 51.2 4e-04
sp|P05080|194K_TRVSY Replicase large subunit OS=Tobacco rattle vi... 51.2 4e-04
sp|Q04610|POLN_HEVMY Non-structural polyprotein pORF1 OS=Hepatiti... 51.2 5e-04
sp|Q9QBU0|RDRP_PMTVS Replicase large subunit OS=Potato mop-top vi... 51.2 5e-04
sp|P69514|RDRP_CGMVS Replicase large subunit OS=Cucumber green mo... 51.2 5e-04
sp|Q9IVZ9|POLN_HEVCT Non-structural polyprotein pORF1 OS=Hepatiti... 50.8 6e-04
sp|Q84133|RDRP_ORSVS Replicase large subunit OS=Odontoglossum rin... 50.8 7e-04
sp|P17595|ALPHA_BSMV Replication protein alpha-A OS=Barley stripe... 50.4 9e-04
sp|P20127|POLR_OYMV RNA replicase polyprotein OS=Ononis yellow mo... 49.7 0.001
sp|Q5UQ92|YR530_MIMIV Uncharacterized protein R530 OS=Acanthamoeb... 48.9 0.002
sp|Q01681|POLG_PPVEA Genome polyprotein (Fragment) OS=Plum pox po... 48.9 0.002
sp|P08411|POLN_SFV Polyprotein P1234 OS=Semliki forest virus OX=1... 48.5 0.003
sp|O56075|POLG_PEMVM Genome polyprotein OS=Peanut mottle virus (s... 48.1 0.005
sp|P09814|POLG_TVMV Genome polyprotein OS=Tobacco vein mottling v... 48.1 0.005
sp|Q58914|Y1519_METJA Uncharacterized protein MJ1519 OS=Methanoca... 47.4 0.006
sp|Q05983|RDRP_RBDVR Methyltransferase/helicase/RNA-directed RNA ... 47.0 0.008
sp|P26627|R1AB_CVMJD Replicase polyprotein 1ab (Fragment) OS=Muri... 46.6 0.010
sp|Q89AB2|RECD_BUCBP RecBCD enzyme subunit RecD OS=Buchnera aphid... 46.2 0.011
sp|Q9YKD6|RDRP_TOMS1 Replicase large subunit OS=Tomato mosaic vir... 46.6 0.012
sp|P17766|POLG_PPVNA Genome polyprotein OS=Plum pox potyvirus (is... 46.6 0.012
sp|Q90069|POLG_SBMVG Genome polyprotein OS=Soybean mosaic virus (... 46.2 0.017
sp|Q5GS59|RLME_WOLTR Ribosomal RNA large subunit methyltransferas... 44.3 0.018
sp|P13529|POLG_PPVD Genome polyprotein OS=Plum pox potyvirus (str... 45.8 0.021
sp|Q65399|POLG_BCMNN Genome polyprotein OS=Bean common mosaic nec... 45.8 0.022
sp|P17767|POLG_PPVRA Genome polyprotein OS=Plum pox potyvirus (st... 45.4 0.025
sp|P32270|DDA_BPT4 ATP-dependent DNA helicase dda OS=Enterobacter... 45.0 0.027
sp|Q54PT1|GDAP2_DICDI Protein GDAP2 homolog OS=Dictyostelium disc... 45.0 0.031
sp|Q83044|R1A_LIYV9 Replicase polyprotein 1a OS=Lettuce infectiou... 45.0 0.032
sp|Q89249|RDRP_SBWMN Replicase large subunit OS=Soil-borne wheat ... 45.0 0.033
sp|Q84934|POLG_PPVSK Genome polyprotein OS=Plum pox potyvirus (st... 45.0 0.034
sp|P89676|RDRP_TOMK2 Replicase large subunit OS=Tomato mosaic vir... 45.0 0.036
sp|Q83045|R1AB_LIYV9 Replicase polyprotein 1ab OS=Lettuce infecti... 45.0 0.038
sp|Q9Q1T8|RDRP_TOMK1 Replicase large subunit OS=Tomato mosaic vir... 45.0 0.038
sp|P03587|RDRP_TOML Replicase large subunit OS=Tomato mosaic viru... 45.0 0.040
sp|P21231|POLG_SBMVN Genome polyprotein OS=Soybean mosaic virus (... 44.7 0.053
sp|Q73L97|RLME_TREDE Ribosomal RNA large subunit methyltransferas... 42.4 0.071
sp|Q73IS9|RLME_WOLPM Ribosomal RNA large subunit methyltransferas... 42.0 0.079
sp|P17765|POLG_BYMV Genome polyprotein OS=Bean yellow mosaic viru... 43.9 0.084
sp|Q5PAN0|RLME_ANAMM Ribosomal RNA large subunit methyltransferas... 41.6 0.11
sp|B9KIP4|RLME_ANAMF Ribosomal RNA large subunit methyltransferas... 41.6 0.11
sp|P45612|UVRD_MYCCT Probable DNA helicase II homolog OS=Mycoplas... 43.1 0.13
sp|Q00020|1A_BBMV Replication protein 1a OS=Broad bean mottle vir... 42.7 0.16
sp|O71188|R1A_GLRV3 Replicase protein 1a OS=Grapevine leafroll-as... 42.7 0.17
sp|P35928|POLR_ELV RNA replicase polyprotein OS=Erysimum latent v... 42.7 0.17
sp|Q9RT63|RECD2_DEIRA ATP-dependent RecD2 DNA helicase OS=Deinoco... 42.7 0.17
sp|O71189|R1AB_GLRV3 Replicase polyprotein 1ab OS=Grapevine leafr... 42.7 0.19
sp|P39369|YJHR_ECOLI Putative uncharacterized protein YjhR OS=Esc... 41.6 0.22
sp|Q65674|TGB1_BNYVS Movement protein TGB1 OS=Beet necrotic yello... 41.6 0.29
sp|Q64962|RDRP_ASPVP RNA replication polyprotein OS=Apple stem pi... 42.0 0.31
sp|A0A0S2T050|RDRP_TBRFV Replicase large subunit OS=Tomato brown ... 41.6 0.41
sp|Q08534|R1AB_BYVU Replicase polyprotein 1ab OS=Beet yellows vir... 41.6 0.46
sp|Q9ILI5|NS1AB_TASV2 Non-structural polyprotein 1AB OS=Turkey as... 41.2 0.48
sp|Q01500|POLG_PEMVC Genome polyprotein OS=Pepper mottle virus (i... 41.2 0.52
sp|Q84687|RDRP_PCV87 Replicase large subunit OS=Peanut clump viru... 41.2 0.56
sp|Q58889|PRS2_METJA Putative 26S proteasome regulatory subunit h... 40.4 0.59
sp|P27752|1A_CCMV Replication protein 1a OS=Cowpea chlorotic mott... 40.8 0.61
sp|Q4FRM3|RS20_PSYA2 Small ribosomal subunit protein bS20 OS=Psyc... 37.0 0.64
sp|P20234|POLG_OMV Genome polyprotein (Fragment) OS=Ornithogalum ... 40.8 0.67
sp|Q5UQ32|RPO6_MIMIV DNA-directed RNA polymerase subunit 6 OS=Aca... 40.4 0.67
sp|O11436|POLG_RGMVD Genome polyprotein OS=Ryegrass mosaic virus ... 40.8 0.70
sp|Q9YQ08|RDRP_TMVB Replicase large subunit OS=Tobacco mosaic vir... 40.8 0.71
sp|B0R461|HTR6_HALS3 Transducer protein Htr6 OS=Halobacterium sal... 40.4 0.73
sp|P15576|NU1M_LEITA NADH-ubiquinone oxidoreductase chain 1 OS=Le... 39.7 0.84
sp|Q2FQC0|KUP_METHJ Probable potassium transport system protein K... 40.0 0.86
sp|F4J0C0|AATPA_ARATH AAA-ATPase At3g28600 OS=Arabidopsis thalian... 40.0 0.87
sp|Q6XW15|POLG_BTMV Genome polyprotein OS=Beet mosaic virus OX=11... 40.4 0.88
sp|P19723|POLG_PRSVP Genome polyprotein (Fragment) OS=Papaya ring... 40.0 0.95
sp|Q91ZC6|MRGA6_MOUSE Mas-related G-protein coupled receptor memb... 39.7 0.97
sp|Q0IE10|UVRB_SYNS3 UvrABC system protein B OS=Synechococcus sp.... 40.0 1.0
sp|P36304|POLR_KYMVJ RNA replicase polyprotein OS=Kennedya yellow... 40.0 1.1
sp|P19724|POLG_PRSVW Genome polyprotein (Fragment) OS=Papaya ring... 40.0 1.1
sp|P28726|1A_PSVJ Replication protein 1a OS=Peanut stunt virus (s... 40.0 1.1
sp|Q88920|RDRP_TVCV Replicase large subunit OS=Turnip vein-cleari... 40.0 1.2
sp|Q3KNA1|MRGB2_MOUSE Mas-related G-protein coupled receptor memb... 39.3 1.2
sp|Q1RGZ3|ATP6_RICBR ATP synthase subunit a OS=Rickettsia bellii ... 38.5 1.5
sp|A8GUJ3|ATP6_RICB8 ATP synthase subunit a OS=Rickettsia bellii ... 38.5 1.5
sp|P30738|RDRP_TMVKR Replicase large subunit OS=Tobacco mosaic vi... 39.7 1.7
sp|B9JA28|ATP6_RHIR8 ATP synthase subunit a OS=Rhizobium rhizogen... 38.5 1.8
sp|Q37376|NU2M_ACACA NADH-ubiquinone oxidoreductase chain 2 OS=Ac... 38.9 1.9
sp|P0DW67|RGYR2_SULAC Reverse gyrase 2 OS=Sulfolobus acidocaldari... 39.3 2.0
sp|Q5NQH8|RLME_ZYMMO Ribosomal RNA large subunit methyltransferas... 38.1 2.0
sp|Q67ES1|TR113_RAT Taste receptor type 2 member 113 OS=Rattus no... 38.5 2.1
sp|A1VC40|RLME_DESVV Ribosomal RNA large subunit methyltransferas... 37.7 2.1
sp|Q729T9|RLME_DESVH Ribosomal RNA large subunit methyltransferas... 37.7 2.1
sp|Q98745|RDRP_TMVRA Replicase large subunit OS=Tobacco mosaic vi... 39.3 2.1
sp|Q66121|1A_CMVIX Replication protein 1a OS=Cucumber mosaic viru... 38.9 2.4
sp|Q83943|1A_OLV2I Replication protein 1a OS=Olive latent virus 2... 38.9 2.4
sp|Q9TC94|YMF16_NEPOL Uncharacterized tatC-like protein ymf16 OS=... 38.1 2.4
sp|P04540|NU5M_TRYBB NADH-ubiquinone oxidoreductase chain 5 OS=Tr... 38.5 2.5
sp|O93058|RDRP_TMVOM Replicase large subunit OS=Tobacco mosaic vi... 38.9 2.6
sp|P26848|NU4M_MARPO NADH-ubiquinone oxidoreductase chain 4 OS=Ma... 38.5 2.6
sp|P90211|RDRP_TMOB Replicase large subunit OS=Tobamovirus Ob OX=... 38.9 2.6
sp|P03586|RDRP_TMV Replicase large subunit OS=Tobacco mosaic viru... 38.9 2.6
sp|P03588|1A_BMV Replication protein 1a OS=Brome mosaic virus OX=... 38.9 2.6
sp|C3MGQ4|RLME_SINFN Ribosomal RNA large subunit methyltransferas... 37.7 2.7
sp|Q9WAL8|POL1_SDVS5 RNA1 polyprotein OS=Satsuma dwarf virus (iso... 38.9 2.8
sp|Q8QL26|Y1070_SIRV1 Uncharacterized protein 1070 OS=Sulfolobus ... 38.5 2.9
sp|Q1RH22|Y1261_RICBR Uncharacterized lipoprotein RBE_1261 OS=Ric... 38.5 3.0
sp|Q04574|POL1_BAYMG Genome polyprotein 1 OS=Barley yellow mosaic... 38.5 3.1
sp|Q9BUN8|DERL1_HUMAN Derlin-1 OS=Homo sapiens OX=9606 GN=DERL1 P... 37.7 3.3
sp|Q71SS4|DERL1_BOVIN Derlin-1 OS=Bos taurus OX=9913 GN=DERL1 PE=... 37.3 3.4
sp|Q5R9W3|DERL1_PONAB Derlin-1 OS=Pongo abelii OX=9601 GN=DERL1 P... 37.3 3.5
sp|Q51151|LCBA_NEIMI Capsular polysaccharide phosphotransferase O... 37.7 3.6
sp|Q971T7|RGYR1_SULTO Reverse gyrase 1 OS=Sulfurisphaera tokodaii... 38.5 3.7
sp|Q92JP0|ATP6_RICCN ATP synthase subunit a OS=Rickettsia conorii... 37.3 3.7
sp|C3PM51|ATP6_RICAE ATP synthase subunit a OS=Rickettsia africae... 37.3 3.9
sp|P29152|POLG_PSBMV Genome polyprotein OS=Pea seed-borne mosaic ... 38.1 4.1
sp|Q9LJJ5|AATPB_ARATH AAA-ATPase At3g28610 OS=Arabidopsis thalian... 37.7 4.1
sp|Q09887|YC9D_SCHPO Uncharacterized amino-acid permease C584.13 ... 38.1 4.1
sp|A8F0C9|ATP6_RICM5 ATP synthase subunit a OS=Rickettsia massili... 37.3 4.2
sp|Q99J56|DERL1_MOUSE Derlin-1 OS=Mus musculus OX=10090 GN=Derl1 ... 37.0 4.6
sp|C4K0P3|ATP6_RICPU ATP synthase subunit a OS=Rickettsia peacock... 37.0 4.9
sp|Q8U221|SYM_PYRFU Methionine--tRNA ligase OS=Pyrococcus furiosu... 37.7 5.3
sp|A8GQF6|ATP6_RICRS ATP synthase subunit a OS=Rickettsia rickett... 37.0 5.6
sp|B0BVU2|ATP6_RICRO ATP synthase subunit a OS=Rickettsia rickett... 37.0 5.6
sp|Q4WFQ4|ABCH_ASPFU ABC multidrug transporter H OS=Aspergillus f... 37.7 6.1
sp|Q5I0E9|S47A1_RAT Multidrug and toxin extrusion protein 1 OS=Ra... 37.3 6.3
sp|A1SSX2|RNFD_PSYIN Ion-translocating oxidoreductase complex sub... 37.0 6.3
sp|Q00167|VG78_ICHVA Putative zinc-binding protein ORF78 OS=Ictal... 37.0 6.5
sp|Q68XQ1|ATP6_RICTY ATP synthase subunit a OS=Rickettsia typhi (... 36.6 6.8
sp|J8HQ06|GAJB_BACC6 Gabija protein GajB OS=Bacillus cereus (stra... 37.0 7.7
sp|Q4UNH7|ATP6_RICFE ATP synthase subunit a OS=Rickettsia felis (... 36.2 7.9
sp|P06011|1A_CMVQ Replication protein 1a OS=Cucumber mosaic virus... 37.0 8.4
sp|Q85BG0|NU4C_ANTAG NAD(P)H-quinone oxidoreductase chain 4, chlo... 37.0 8.8
sp|O40976|1A_CMVNT Replication protein 1a OS=Cucumber mosaic viru... 37.0 9.0
sp|P17769|1A_CMVFN Replication protein 1a OS=Cucumber mosaic viru... 37.0 9.2
sp|F4KIB2|TMN8_ARATH Transmembrane 9 superfamily member 8 OS=Arab... 37.0 9.3
sp|Q91ZC7|MRGA5_MOUSE Mas-related G-protein coupled receptor memb... 36.2 9.8
>sp|P0C6X7|R1AB_SARS Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus OX=694009 GN=rep PE=1 SV=1
Length=7073
Score = 10842 bits (28135), Expect = 0.0, Method: Composition-based stats.
Identities = 7073/7073 (100%), Positives = 7073/7073 (100%), Gaps = 0/7073 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW
Sbjct 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL
Sbjct 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY
Sbjct 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV
Sbjct 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC
Sbjct 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV
Sbjct 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL
Sbjct 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
Query 961 PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC 1020
PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC
Sbjct 961 PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC 1020
Query 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS
Sbjct 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
Query 1081 CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL 1140
CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL
Sbjct 1081 CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL 1140
Query 1141 QVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK 1200
QVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK
Sbjct 1141 QVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK 1200
Query 1201 PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP 1260
PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP
Sbjct 1201 PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP 1260
Query 1261 YMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKT 1320
YMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKT
Sbjct 1261 YMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKT 1320
Query 1321 ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQR 1380
ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQR
Sbjct 1321 ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQR 1380
Query 1381 KYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAAR 1440
KYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAAR
Sbjct 1381 KYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAAR 1440
Query 1441 CMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG 1500
CMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG
Sbjct 1441 CMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG 1500
Query 1501 VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQL 1560
VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQL
Sbjct 1501 VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQL 1560
Query 1561 VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFL 1620
VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFL
Sbjct 1561 VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFL 1620
Query 1621 GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR 1680
GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR
Sbjct 1621 GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR 1680
Query 1681 AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT 1740
AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT
Sbjct 1681 AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT 1740
Query 1741 GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC 1800
GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC
Sbjct 1741 GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC 1800
Query 1801 ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYK 1860
ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYK
Sbjct 1801 ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYK 1860
Query 1861 LDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQ 1920
LDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQ
Sbjct 1861 LDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQ 1920
Query 1921 MTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF 1980
MTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF
Sbjct 1921 MTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF 1980
Query 1981 KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE 2040
KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE
Sbjct 1981 KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE 2040
Query 2041 CDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA 2100
CDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA
Sbjct 2041 CDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA 2100
Query 2101 THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFT 2160
THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFT
Sbjct 2101 THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFT 2160
Query 2161 KSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSL 2220
KSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSL
Sbjct 2161 KSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSL 2220
Query 2221 ICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPA 2280
ICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPA
Sbjct 2221 ICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPA 2280
Query 2281 LETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW 2340
LETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW
Sbjct 2281 LETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW 2340
Query 2341 LMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC 2400
LMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC
Sbjct 2341 LMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC 2400
Query 2401 TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINP 2460
TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINP
Sbjct 2401 TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINP 2460
Query 2461 TDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVF 2520
TDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVF
Sbjct 2461 TDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVF 2520
Query 2521 DGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFS 2580
DGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFS
Sbjct 2521 DGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFS 2580
Query 2581 VPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDL 2640
VPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDL
Sbjct 2581 VPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDL 2640
Query 2641 EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE 2700
EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE
Sbjct 2641 EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE 2700
Query 2701 QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLA 2760
QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLA
Sbjct 2701 QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLA 2760
Query 2761 ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG 2820
ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG
Sbjct 2761 ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG 2820
Query 2821 SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLI 2880
SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLI
Sbjct 2821 SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLI 2880
Query 2881 EYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQ 2940
EYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQ
Sbjct 2881 EYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQ 2940
Query 2941 FPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA 3000
FPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA
Sbjct 2941 FPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA 3000
Query 3001 MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANAL 3060
MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANAL
Sbjct 3001 MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANAL 3060
Query 3061 LFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAI 3120
LFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAI
Sbjct 3061 LFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAI 3120
Query 3121 YVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ 3180
YVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ
Sbjct 3121 YVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ 3180
Query 3181 YNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQ 3240
YNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQ
Sbjct 3181 YNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQ 3240
Query 3241 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3300
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR
Sbjct 3241 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3300
Query 3301 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3301 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
Query 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK
Sbjct 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
Query 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
Query 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC
Sbjct 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
Query 3541 SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA 3600
SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA
Sbjct 3541 SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA 3600
Query 3601 CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCV 3660
CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCV
Sbjct 3601 CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCV 3660
Query 3661 MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN 3720
MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN
Sbjct 3661 MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN 3720
Query 3721 YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY
Sbjct 3721 YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
Query 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS
Sbjct 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
Query 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG
Sbjct 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
Query 3901 AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKS 3960
AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKS
Sbjct 3901 AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKS 3960
Query 3961 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4020
LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND
Sbjct 3961 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4020
Query 4021 ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD 4080
ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD
Sbjct 4021 ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD 4080
Query 4081 ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTAC 4140
ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTAC
Sbjct 4081 ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTAC 4140
Query 4141 TDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP 4200
TDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP
Sbjct 4141 TDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP 4200
Query 4201 KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDY 4260
KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDY
Sbjct 4201 KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDY 4260
Query 4261 LASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFC 4320
LASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFC
Sbjct 4261 LASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFC 4320
Query 4321 DLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRV 4380
DLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRV
Sbjct 4321 DLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRV 4380
Query 4381 CGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFV 4440
CGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFV
Sbjct 4381 CGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFV 4440
Query 4441 VKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYAL 4500
VKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYAL
Sbjct 4441 VKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYAL 4500
Query 4501 RHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQ 4560
RHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQ
Sbjct 4501 RHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQ 4560
Query 4561 FCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRAL 4620
FCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRAL
Sbjct 4561 FCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRAL 4620
Query 4621 AAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCA 4680
AAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCA
Sbjct 4621 AAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCA 4680
Query 4681 NFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKEL 4740
NFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKEL
Sbjct 4681 NFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKEL 4740
Query 4741 LVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKE 4800
LVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKE
Sbjct 4741 LVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKE 4800
Query 4801 GSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINAN 4860
GSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINAN
Sbjct 4801 GSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINAN 4860
Query 4861 QVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAK 4920
QVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAK
Sbjct 4861 QVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAK 4920
Query 4921 NRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
NRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET
Sbjct 4921 NRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
Query 4981 PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGG 5040
PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGG
Sbjct 4981 PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGG 5040
Query 5041 SLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECL 5100
SLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECL
Sbjct 5041 SLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECL 5100
Query 5101 YRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNN 5160
YRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNN
Sbjct 5101 YRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNN 5160
Query 5161 VFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTD 5220
VFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTD
Sbjct 5161 VFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTD 5220
Query 5221 GTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDN 5280
GTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDN
Sbjct 5221 GTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDN 5280
Query 5281 TSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSH 5340
TSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSH
Sbjct 5281 TSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSH 5340
Query 5341 KLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVG 5400
KLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVG
Sbjct 5341 KLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVG 5400
Query 5401 SDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLS 5460
SDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLS
Sbjct 5401 SDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLS 5460
Query 5461 DRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKL 5520
DRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKL
Sbjct 5461 DRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKL 5520
Query 5521 NVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYST 5580
NVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYST
Sbjct 5521 NVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYST 5580
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR
Sbjct 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI
Sbjct 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
Query 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN
Sbjct 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
Query 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN
Sbjct 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
Query 5821 AVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDR 5880
AVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDR
Sbjct 5821 AVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDR 5880
Query 5881 DLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGL 5940
DLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGL
Sbjct 5881 DLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGL 5940
Query 5941 CVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR 6000
CVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR
Sbjct 5941 CVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATR 6000
Query 6001 DAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLP 6060
DAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLP
Sbjct 6001 DAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLP 6060
Query 6061 WNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFS 6120
WNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFS
Sbjct 6061 WNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFS 6120
Query 6121 TSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTR 6180
TSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTR
Sbjct 6121 TSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTR 6180
Query 6181 CLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAI 6240
CLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAI
Sbjct 6181 CLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAI 6240
Query 6241 KCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIV 6300
KCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIV
Sbjct 6241 KCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIV 6300
Query 6301 CRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQ 6360
CRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQ
Sbjct 6301 CRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQ 6360
Query 6361 VVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYN 6420
VVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYN
Sbjct 6361 VVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYN 6420
Query 6421 LWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPV 6480
LWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPV
Sbjct 6421 LWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPV 6480
Query 6481 NVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKP 6540
NVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKP
Sbjct 6481 NVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKP 6540
Query 6541 TESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGES 6600
TESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGES
Sbjct 6541 TESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGES 6600
Query 6601 VKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYA 6660
VKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYA
Sbjct 6601 VKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYA 6660
Query 6661 FEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCV 6720
FEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCV
Sbjct 6661 FEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCV 6720
Query 6721 CSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAW 6780
CSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAW
Sbjct 6721 CSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAW 6780
Query 6781 QPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNM 6840
QPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNM
Sbjct 6781 QPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNM 6840
Query 6841 RVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWD 6900
RVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWD
Sbjct 6841 RVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWD 6900
Query 6901 LIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMG 6960
LIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMG
Sbjct 6901 LIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMG 6960
Query 6961 HFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLF 7020
HFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLF
Sbjct 6961 HFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLF 7020
Query 7021 DMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
DMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN
Sbjct 7021 DMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
>sp|P0C6W6|R1AB_BCRP3 Replicase polyprotein 1ab OS=Bat coronavirus
Rp3/2004 OX=349344 GN=rep PE=3 SV=1
Length=7071
Score = 10786 bits (27990), Expect = 0.0, Method: Composition-based stats.
Identities = 6897/7074 (97%), Positives = 6982/7074 (99%), Gaps = 4/7074 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLVLG+NEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLK+GTCG+VELEKGV
Sbjct 1 MESLVLGINEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKSGTCGIVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQ EQPYVFIKRSDA T+HGH+V ELVAE+DG+QYGRSGITLGVLVPHVGETPIAYRN
Sbjct 61 LPQPEQPYVFIKRSDAQGTDHGHRVRELVAELDGVQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHS+GIDLKSYDLGDELGTDPIEDYEQNWNTKHGSG LRELTRELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGVLRELTRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
A+TRYVDNNFCGPDGYPL+CIKD LARAGKSMCTLSEQLDYIESKRGVYCCRDH HEIAW
Sbjct 181 ALTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCRDHGHEIAW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVA+PQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCE CGTENLV EGP TCGYL
Sbjct 301 RSVYPVATPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVSEGPNTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
PTNAVVKMPCPACQDPEIGPEHS ADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSAADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDF LNEEVAIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFQLNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKP+KGAWNIGQ RSVLTPLCGFPSQA
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPIKGAWNIGQHRSVLTPLCGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIF+RTLDAANHSIPDLQRAAVTILD ISEQSLRLVDAMVYTS+LLTNSVIIMAY
Sbjct 541 AGVIRSIFSRTLDAANHSIPDLQRAAVTILDSISEQSLRLVDAMVYTSNLLTNSVIIMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQTSQWLSNLL TTVEKLRPIF WIEAKLSAGVEFLKDAWEILKFLITGVFDIV
Sbjct 601 VTGGLVQQTSQWLSNLLDTTVEKLRPIFAWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVASDNIKDCVKCF+DVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC
Sbjct 661 KGQIQVASDNIKDCVKCFVDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGA+VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAVVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVC+NGLMLLEIK EQYCALSPGLLATNNVFRLKGGAP KGVTFGEDTV EVQGYKNV
Sbjct 781 TPVCINGLMLLEIKANEQYCALSPGLLATNNVFRLKGGAPTKGVTFGEDTVVEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDE-TCEHEYGTEDDYQG 959
WSVATFYLFDD+GEE SSRMYCSFYPPDEEE+ + EEEE+ E TCEHEYGTE+DY+G
Sbjct 901 WSVATFYLFDDSGEEKLSSRMYCSFYPPDEEEDCEEYEEEEEVSERTCEHEYGTEEDYKG 960
Query 960 LPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
LPLEFGAS + ++VEE+EEEDWLDD E EPEPEP EEPVNQ TGYLKLTDNVAIK
Sbjct 961 LPLEFGASTDIIQVEEQEEEDWLDD---AVEAEPEPEPLHEEPVNQLTGYLKLTDNVAIK 1017
Query 1020 CVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGG 1079
CVDIV+EAQ+ANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESD YIKLNGPLTVGG
Sbjct 1018 CVDIVEEAQNANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDHYIKLNGPLTVGG 1077
Query 1080 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1139
SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS
Sbjct 1078 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1137
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQ 1199
LQ+CVQTVRTQVYI VNDK LYEQVVMDYLD+LKP+VEAPKQE P E K +EKSVVQ
Sbjct 1138 LQMCVQTVRTQVYIVVNDKVLYEQVVMDYLDSLKPKVEAPKQEVLPKAEYPKVDEKSVVQ 1197
Query 1200 KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDA 1259
K +DVKPKIKACIDEVTTTLEETKFLTNKLLLF DINGKLY DS+NMLRGEDMSFLEKDA
Sbjct 1198 KTIDVKPKIKACIDEVTTTLEETKFLTNKLLLFTDINGKLYQDSKNMLRGEDMSFLEKDA 1257
Query 1260 PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAK 1319
PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVP++EYITTYPGQGCAGYTLEEAK
Sbjct 1258 PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPINEYITTYPGQGCAGYTLEEAK 1317
Query 1320 TALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQ 1379
TALKKCKSAFYVLPSE PNAKEEILGTVSWNLREMLAHAEETRKLMP+CMDVRAIMATIQ
Sbjct 1318 TALKKCKSAFYVLPSETPNAKEEILGTVSWNLREMLAHAEETRKLMPVCMDVRAIMATIQ 1377
Query 1380 RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA 1439
RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA
Sbjct 1378 RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA 1437
Query 1440 RCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTEL 1499
RCMRSLKAPA+VSVSSPDAVTTYNGYLTSSSKTSE+HFVETVSLAGSYRDWSYSGQRTEL
Sbjct 1438 RCMRSLKAPAIVSVSSPDAVTTYNGYLTSSSKTSEDHFVETVSLAGSYRDWSYSGQRTEL 1497
Query 1500 GVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQ 1559
GVEFLKRG+KIVYHTLESPV+FHLDGEVL LDKLKSLLSLREVKTIKVFTTVDNTNLHTQ
Sbjct 1498 GVEFLKRGEKIVYHTLESPVKFHLDGEVLPLDKLKSLLSLREVKTIKVFTTVDNTNLHTQ 1557
Query 1560 LVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF 1619
LVDMSMTYGQQ GPTYL+GADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF
Sbjct 1558 LVDMSMTYGQQLGPTYLEGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF 1617
Query 1620 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRA 1679
LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ+EVKFNAPALQEAYYRA
Sbjct 1618 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQIEVKFNAPALQEAYYRA 1677
Query 1680 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1739
RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL
Sbjct 1678 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1737
Query 1740 TGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL 1799
TGVEAVMYMGTLSYDNLK GVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL
Sbjct 1738 TGVEAVMYMGTLSYDNLKMGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL 1797
Query 1800 CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY 1859
CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY
Sbjct 1798 CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY 1857
Query 1860 KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLN 1919
KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL+PTQPLPNASFDNFKLTCSNTKFADDLN
Sbjct 1858 KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLIPTQPLPNASFDNFKLTCSNTKFADDLN 1917
Query 1920 QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT 1979
QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT
Sbjct 1918 QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT 1977
Query 1980 FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVI 2039
FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPT EEVVENPTIQKEVI
Sbjct 1978 FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTPEEVVENPTIQKEVI 2037
Query 2040 ECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTI 2099
ECDVKTTEVVGNVILKPSDEGVKVTQEL HEDLMAAYVENTSITIKKPNELSLALGLKTI
Sbjct 2038 ECDVKTTEVVGNVILKPSDEGVKVTQELDHEDLMAAYVENTSITIKKPNELSLALGLKTI 2097
Query 2100 ATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTF 2159
ATHGIAAINSVPW KILAYVKPFLGQAA+TTSNCAKRL QR+FNNYMPYV TLLFQLCTF
Sbjct 2098 ATHGIAAINSVPWGKILAYVKPFLGQAAVTTSNCAKRLVQRMFNNYMPYVLTLLFQLCTF 2157
Query 2160 TKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS 2219
TKSTNSRIRASLPTTIAKNSV+ + +LCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS
Sbjct 2158 TKSTNSRIRASLPTTIAKNSVRGIVRLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS 2217
Query 2220 LICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYP 2279
LI VTAA GVLLSNFGAPSYC+GVRE YLNSSNVTTMDFCEGSFPCS+CLSGLDSLDSYP
Sbjct 2218 LIYVTAALGVLLSNFGAPSYCSGVRESYLNSSNVTTMDFCEGSFPCSVCLSGLDSLDSYP 2277
Query 2280 ALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2339
ALETIQVTISSYKLDLTILGLAAEW AYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS
Sbjct 2278 ALETIQVTISSYKLDLTILGLAAEWFFAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2337
Query 2340 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2399
WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE
Sbjct 2338 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2397
Query 2400 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPIN 2459
CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFC GSTFISDEVARDLSLQFKRPIN
Sbjct 2398 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCAGSTFISDEVARDLSLQFKRPIN 2457
Query 2460 PTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2519
PTDQSSY+VDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV
Sbjct 2458 PTDQSSYVVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2517
Query 2520 FDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2579
FDGKSKCDESA+KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF
Sbjct 2518 FDGKSKCDESAAKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2577
Query 2580 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD 2639
SVPMEKLKALVATAHSELAKGVALDGVLSTFVSA+RQGVVDTDVDTKDVIECLKLSHHSD
Sbjct 2578 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSASRQGVVDTDVDTKDVIECLKLSHHSD 2637
Query 2640 LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLS 2699
LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVA+SHNVSLIWNVKDYMSLS
Sbjct 2638 LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVARSHNVSLIWNVKDYMSLS 2697
Query 2700 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVL 2759
EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVST FK+MLKATLLCVL
Sbjct 2698 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTWFKIMLKATLLCVL 2757
Query 2760 AALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRG 2819
AALVCYIVMPVH LS+H GYTNEIIGYKAIQDGVTRDI+STDDCFANKHAGFD+WFSQRG
Sbjct 2758 AALVCYIVMPVHILSVHGGYTNEIIGYKAIQDGVTRDIVSTDDCFANKHAGFDSWFSQRG 2817
Query 2820 GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL
Sbjct 2818 GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2877
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2939
IEYSDF+TSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII
Sbjct 2878 IEYSDFSTSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2937
Query 2940 QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVD 2999
QFPN YLEGSVRVVTTFDAEYCRHGTCERSE GICLSTSGRWVLNNEHYRAL GVFCGVD
Sbjct 2938 QFPNAYLEGSVRVVTTFDAEYCRHGTCERSEAGICLSTSGRWVLNNEHYRALPGVFCGVD 2997
Query 3000 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANA 3059
AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRR FGEYNHVVAANA
Sbjct 2998 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRAFGEYNHVVAANA 3057
Query 3060 LLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3119
LFLMSFTILCL PAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA
Sbjct 3058 PLFLMSFTILCLAPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3117
Query 3120 IYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3179
IYVFCISLKH HWFFNNYLRKRV+FNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT
Sbjct 3118 IYVFCISLKHFHWFFNNYLRKRVVFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3177
Query 3180 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3239
QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL
Sbjct 3178 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3237
Query 3240 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI 3299
QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI
Sbjct 3238 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI 3297
Query 3300 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3359
RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN
Sbjct 3298 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3357
Query 3360 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3419
GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT VHAGTDLEG
Sbjct 3358 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTEVHAGTDLEG 3417
Query 3420 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3479
KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY
Sbjct 3418 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3477
Query 3480 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3539
EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ
Sbjct 3478 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3537
Query 3540 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIA 3599
CSGVTFQGKFK+IVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA+A
Sbjct 3538 CSGVTFQGKFKRIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAVA 3597
Query 3600 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3659
ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC
Sbjct 3598 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3657
Query 3660 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3719
VMYASALVLL+LMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS
Sbjct 3658 VMYASALVLLVLMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3717
Query 3720 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3779
NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR
Sbjct 3718 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3777
Query 3780 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3839
YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM
Sbjct 3778 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3837
Query 3840 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3899
SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ
Sbjct 3838 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3897
Query 3900 GAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3959
GAVDIN+LCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK
Sbjct 3898 GAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3957
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
SLNVAKSEFDR+AAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN
Sbjct 3958 SLNVAKSEFDRNAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4017
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV
Sbjct 4018 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4077
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4139
DADSKIVQLSEINM+NS NLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA
Sbjct 4078 DADSKIVQLSEINMENSSNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4137
Query 4140 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4199
CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG
Sbjct 4138 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4197
Query 4200 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4259
PKVKYL+FIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD
Sbjct 4198 PKVKYLHFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4257
Query 4260 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4319
YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF
Sbjct 4258 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4317
Query 4320 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP+MQSADASTFLNR
Sbjct 4318 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPMMQSADASTFLNR 4377
Query 4380 VCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF 4439
VCGVSAARLTPCGTG STDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF
Sbjct 4378 VCGVSAARLTPCGTGISTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF 4437
Query 4440 VVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA 4499
VVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA
Sbjct 4438 VVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA 4497
Query 4500 LRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTV 4559
LRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQ+LLKTV
Sbjct 4498 LRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTV 4557
Query 4560 QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRA 4619
QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRA
Sbjct 4558 QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRA 4617
Query 4620 LAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHC 4679
LAAESHMDADLAKPLIKWDLLKYDFT ERLCLFDRYFKYWDQTYHPNCINCLDDRCILHC
Sbjct 4618 LAAESHMDADLAKPLIKWDLLKYDFTAERLCLFDRYFKYWDQTYHPNCINCLDDRCILHC 4677
Query 4680 ANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKE 4739
ANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKE
Sbjct 4678 ANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKE 4737
Query 4740 LLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFK 4799
LLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFK
Sbjct 4738 LLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFK 4797
Query 4800 EGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA 4859
EGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA
Sbjct 4798 EGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA 4857
Query 4860 NQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISA 4919
NQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISA
Sbjct 4858 NQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISA 4917
Query 4920 KNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE 4979
KNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE
Sbjct 4918 KNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE 4977
Query 4980 TPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCG 5039
TPHLMGWDYPKCDRAMPNMLRIMASLVLARKH+TCCNLSHRFYRLANECAQVLSEMVMCG
Sbjct 4978 TPHLMGWDYPKCDRAMPNMLRIMASLVLARKHSTCCNLSHRFYRLANECAQVLSEMVMCG 5037
Query 5040 GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYEC 5099
GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYEC
Sbjct 5038 GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYEC 5097
Query 5100 LYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQN 5159
LYRNRDVDHEFV EFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQN
Sbjct 5098 LYRNRDVDHEFVGEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQN 5157
Query 5160 NVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKT 5219
NVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKT
Sbjct 5158 NVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKT 5217
Query 5220 DGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTND 5279
DGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTND
Sbjct 5218 DGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTND 5277
Query 5280 NTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTS 5339
NTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTS
Sbjct 5278 NTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTS 5337
Query 5340 HKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCV 5399
HKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCV
Sbjct 5338 HKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCV 5397
Query 5400 GSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVL 5459
GSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVL
Sbjct 5398 GSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVL 5457
Query 5460 SDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYK 5519
SDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYK
Sbjct 5458 SDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYK 5517
Query 5520 LNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYS 5579
LN+GDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYS
Sbjct 5518 LNIGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYS 5577
Query 5580 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA 5639
TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA
Sbjct 5578 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA 5637
Query 5640 RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY 5699
RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY
Sbjct 5638 RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY 5697
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD
Sbjct 5698 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5757
Query 5760 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5819
NKLKAHK+KSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ
Sbjct 5758 NKLKAHKEKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5817
Query 5820 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD 5879
NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD
Sbjct 5818 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD 5877
Query 5880 RDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEG 5939
RDLYDKLQFTSLE+PRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVD KFKTEG
Sbjct 5878 RDLYDKLQFTSLEVPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDTKFKTEG 5937
Query 5940 LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHAT 5999
LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHAT
Sbjct 5938 LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHAT 5997
Query 6000 RDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGL 6059
RDAVGTNLPLQLGFSTGVNLVA+PTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGL
Sbjct 5998 RDAVGTNLPLQLGFSTGVNLVAIPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGL 6057
Query 6060 PWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCF 6119
PWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCF
Sbjct 6058 PWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCF 6117
Query 6120 STSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMT 6179
STSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMT
Sbjct 6118 STSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMT 6177
Query 6180 RCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKA 6239
RCLAVHECFVKRVDWSVEYPIIGDEL++NSACRKVQHMVVKSALLADKFPVLHDIGNPKA
Sbjct 6178 RCLAVHECFVKRVDWSVEYPIIGDELKINSACRKVQHMVVKSALLADKFPVLHDIGNPKA 6237
Query 6240 IKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAI 6299
IKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAI
Sbjct 6238 IKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAI 6297
Query 6300 VCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGK 6359
VCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGK
Sbjct 6298 VCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGK 6357
Query 6360 QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTY 6419
QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTY
Sbjct 6358 QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTY 6417
Query 6420 NLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLP 6479
NLWNTFTRLQSLENVAYNVVNKGHFDG AGE PVSIINNAVYTKVDG DVEIFENKTTLP
Sbjct 6418 NLWNTFTRLQSLENVAYNVVNKGHFDGQAGETPVSIINNAVYTKVDGFDVEIFENKTTLP 6477
Query 6480 VNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKK 6539
VNVAFELWAKRNIK VPEIKILNNLGVDIAANTVIWD+KREAP H+STIGVCTMTDIAKK
Sbjct 6478 VNVAFELWAKRNIKSVPEIKILNNLGVDIAANTVIWDHKREAPVHMSTIGVCTMTDIAKK 6537
Query 6540 PTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGE 6599
PTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGE
Sbjct 6538 PTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGE 6597
Query 6600 SVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGY 6659
SVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGY
Sbjct 6598 SVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGY 6657
Query 6660 AFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKC 6719
AFEHIVYGDFSHGQLGGLHLMIGLAKRS+DSPLKLEDFIPMDSTVKNYFITDAQTGSSKC
Sbjct 6658 AFEHIVYGDFSHGQLGGLHLMIGLAKRSRDSPLKLEDFIPMDSTVKNYFITDAQTGSSKC 6717
Query 6720 VCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQA 6779
VCSVIDLLLDDFVEIIKSQDLSV+SKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQA
Sbjct 6718 VCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQA 6777
Query 6780 WQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYN 6839
WQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYN
Sbjct 6778 WQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYN 6837
Query 6840 MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW 6899
MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW
Sbjct 6838 MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW 6897
Query 6900 DLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLM 6959
DLI+SDMYDP+ KHVTKENDSKEGFFTYLCGFIKQKLALGGS+AVKITEHSWNADLYKLM
Sbjct 6898 DLIVSDMYDPKAKHVTKENDSKEGFFTYLCGFIKQKLALGGSVAVKITEHSWNADLYKLM 6957
Query 6960 GHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSL 7019
GHFSWWTAFVTNVNASSSEAFLIG NYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSL
Sbjct 6958 GHFSWWTAFVTNVNASSSEAFLIGVNYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSL 7017
Query 7020 FDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
FDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN
Sbjct 7018 FDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7071
>sp|P0C6V9|R1AB_BC279 Replicase polyprotein 1ab OS=Bat coronavirus
279/2005 OX=389167 GN=rep PE=3 SV=1
Length=7079
Score = 10699 bits (27764), Expect = 0.0, Method: Composition-based stats.
Identities = 6756/7084 (95%), Positives = 6914/7084 (98%), Gaps = 16/7084 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESL LGV+EKTHVQLSLPVLQVRDVLVRGFGDSVEEAL+EAREHLKNGTCGLVELEKGV
Sbjct 1 MESLALGVSEKTHVQLSLPVLQVRDVLVRGFGDSVEEALAEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDA TNHG+KVVELVAE+DGIQYGRSG TLGVLVPHVGETP+AYRN
Sbjct 61 LPQLEQPYVFIKRSDAQGTNHGYKVVELVAELDGIQYGRSGTTLGVLVPHVGETPVAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHSYGIDLKSYDLG ELGTDPIEDYEQNWNTKHG G LREL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGVELGTDPIEDYEQNWNTKHGGGVLRELIRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGKSMCTLSEQLDYIESKRGVYCCR+HEHEI W
Sbjct 181 AFTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERS+KSYE QTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSEKSYERQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVA+PQECN+MHLSTLMKCNHCDEVSWQTCDFLKATCE CGTENLV EGPTTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
P NAVVKMPCPACQDPE+GPEHSVADYHNHSNIETRLRKGGRT+CFGGCVFAYVGCYNKR
Sbjct 361 PANAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASA+IG+ HTGITGDNVETLNEDL+EIL+R+RVNINIVGDFHLNEEVAIILASF
Sbjct 421 AYWVPRASANIGASHTGITGDNVETLNEDLMEILNRDRVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SAST AF+DT+K LDYK+FK IVESCGN+KVT+G+ KGAWNIGQ++S+LTPL GFPSQA
Sbjct 481 SASTCAFVDTVKGLDYKTFKDIVESCGNFKVTRGRAKKGAWNIGQEKSILTPLYGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIF R LD ANHSIPDLQRAA+TILDGISEQSLRL+DAMVYTSDLLTNSVI+MAY
Sbjct 541 AGVIRSIFTRALDTANHSIPDLQRAAITILDGISEQSLRLIDAMVYTSDLLTNSVIVMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQ +QWLSN+LGTTV+KL+P+F W+EAKLSAG+EFL+DAWEILKFL+TGVFDIV
Sbjct 601 VTGGLVQQITQWLSNMLGTTVDKLKPVFTWVEAKLSAGIEFLRDAWEILKFLVTGVFDIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVASDN+K+CVK F+DV+NKALEMCIDQV IAGAKLR+LNLGEVFIAQSKGLYRQC
Sbjct 661 KGQIQVASDNLKECVKAFLDVLNKALEMCIDQVIIAGAKLRTLNLGEVFIAQSKGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPL+APKEVTF EGDSHDTV TSEEVVLKNGELEALETPVDSFTNGA++G
Sbjct 721 IRGKEQLQLLMPLRAPKEVTFFEGDSHDTVFTSEEVVLKNGELEALETPVDSFTNGAVIG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVCVNGLMLLE+KDKEQYCALSPGLLATNNVF LKGGAP+KGVTFGEDTV EVQGYKNV
Sbjct 781 TPVCVNGLMLLELKDKEQYCALSPGLLATNNVFSLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
+ITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
Sbjct 841 KITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCE-HEYGTEDDYQG 959
WSVATFYLFDDAGEE SSRMYCSFYPPDEEE+ + +EEEI E HEYGTEDDY+G
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEEYEDEEEIPEETCEHEYGTEDDYKG 960
Query 960 LPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
LPLEFGAS E +++ +EE+ D E +PEPEP PEEPVNQFTGYLKLTDNVAIK
Sbjct 961 LPLEFGASTE---IQQVDEEEEEDWLEEAIAAKPEPEPLPEEPVNQFTGYLKLTDNVAIK 1017
Query 1020 CVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGG 1079
CVDIVKEAQ A P VIVNAAN+HLKHGGGVAGALNKATNGAMQ+ESDDYIK NGPLTVGG
Sbjct 1018 CVDIVKEAQHAKPTVIVNAANVHLKHGGGVAGALNKATNGAMQQESDDYIKKNGPLTVGG 1077
Query 1080 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1139
SCLLSGHNLAKKC+HVVGPNLNAGED+QLLKAAY NFNSQD+LLAPLLSAGIFGAKPLQS
Sbjct 1078 SCLLSGHNLAKKCMHVVGPNLNAGEDVQLLKAAYANFNSQDVLLAPLLSAGIFGAKPLQS 1137
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTE------ 1193
L++CV+TVRTQVY AVND+ LY+ VV+ YLD+LKP+VE P QE E E
Sbjct 1138 LKMCVETVRTQVYFAVNDQDLYDHVVLGYLDSLKPKVETPTQENLELKEQPAVETLTQEN 1197
Query 1194 ----EKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRG 1249
E V++KPVDV K KA I+EV T+LEETKFLT++LLLFADINGKLY DSQNMLRG
Sbjct 1198 LELEELPVIEKPVDV--KFKARIEEVNTSLEETKFLTSRLLLFADINGKLYQDSQNMLRG 1255
Query 1250 EDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQG 1309
EDM FLEKDAPY+VGDVI+SGDITCV+IP+KKAGGTTEML++ALKKVPV EYITTYPGQG
Sbjct 1256 EDMFFLEKDAPYIVGDVISSGDITCVIIPAKKAGGTTEMLAKALKKVPVSEYITTYPGQG 1315
Query 1310 CAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICM 1369
CAGYTLEEAKTAL+KCKS FYVLPS+ PN KEEILGTVSWNLREMLAHAEETRKLM ICM
Sbjct 1316 CAGYTLEEAKTALRKCKSVFYVLPSKTPNDKEEILGTVSWNLREMLAHAEETRKLMLICM 1375
Query 1370 DVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYV 1429
DV+A+M+TI R+YKGIK+QEGIVDYGVRFFFYTSKEPVASIITKLN LNEPLVTMPIGYV
Sbjct 1376 DVKALMSTIHRRYKGIKVQEGIVDYGVRFFFYTSKEPVASIITKLNLLNEPLVTMPIGYV 1435
Query 1430 THGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRD 1489
THG NLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHF+ETVSLAG YRD
Sbjct 1436 THGLNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFIETVSLAGMYRD 1495
Query 1490 WSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFT 1549
WSYSGQRTELGVEFLKRGDK+VYHT+ SP++FHLDGEVL LDKLKSLLSLREV+TIKVFT
Sbjct 1496 WSYSGQRTELGVEFLKRGDKVVYHTVGSPIQFHLDGEVLLLDKLKSLLSLREVRTIKVFT 1555
Query 1550 TVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAF 1609
TVDNTNLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH HEGKTFFVLPSDDTLRSEAF
Sbjct 1556 TVDNTNLHTQIVDMSMTYGQQFGPTYLDGADVTKIKPHAKHEGKTFFVLPSDDTLRSEAF 1615
Query 1610 EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNA 1669
EYYHTLDESFLGRYMSALNHTKKWKFPQ+GGLTSIKWADNNCYLSSVLLALQQ+EVKFNA
Sbjct 1616 EYYHTLDESFLGRYMSALNHTKKWKFPQIGGLTSIKWADNNCYLSSVLLALQQIEVKFNA 1675
Query 1670 PALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVC 1729
PALQEAYYRARAGDAANFCALILAYSN+TVGELGDVRETMTHLLQHANLESAKRVLNVVC
Sbjct 1676 PALQEAYYRARAGDAANFCALILAYSNRTVGELGDVRETMTHLLQHANLESAKRVLNVVC 1735
Query 1730 KHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPA 1789
K CGQK+TTLTGVEAVMYMGTLSY+ LKTGV+IPC+CGRDATQYLVQQESSFVMMSAPP+
Sbjct 1736 KTCGQKSTTLTGVEAVMYMGTLSYEELKTGVTIPCICGRDATQYLVQQESSFVMMSAPPS 1795
Query 1790 EYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETS 1849
EY LQQG FLCANEYTG+YQCGHYTH+T KETLYRIDGA+LTKMSEYKGPVTDVFYKE S
Sbjct 1796 EYTLQQGAFLCANEYTGSYQCGHYTHVTVKETLYRIDGAYLTKMSEYKGPVTDVFYKEIS 1855
Query 1850 YTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTC 1909
YTTTIKPVSYKLDGV YTEI+PKLD YYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTC
Sbjct 1856 YTTTIKPVSYKLDGVIYTEIQPKLDEYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTC 1915
Query 1910 SNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVW 1969
SNTKFADDLNQMTGF KPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPI+W
Sbjct 1916 SNTKFADDLNQMTGFKKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIIW 1975
Query 1970 HINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVV 2029
HINQ T KTT+KPNTWCLRCLWSTKPV+TSNSFEVL VEDTQGMDNLACESQ PTSEEVV
Sbjct 1976 HINQTTNKTTYKPNTWCLRCLWSTKPVETSNSFEVLEVEDTQGMDNLACESQTPTSEEVV 2035
Query 2030 ENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNE 2089
ENPTIQKEVIECDVKT EVVGNVILKPS+EGVKVTQELGHEDLMAAYVE TSITIKKPNE
Sbjct 2036 ENPTIQKEVIECDVKTIEVVGNVILKPSEEGVKVTQELGHEDLMAAYVEETSITIKKPNE 2095
Query 2090 LSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYV 2149
LSLALGL+T+ATHG AAINSVPWSKILAYVKPFLGQAA+TT+NC KR QRVFNNYMPYV
Sbjct 2096 LSLALGLRTLATHGAAAINSVPWSKILAYVKPFLGQAAVTTTNCIKRCVQRVFNNYMPYV 2155
Query 2150 FTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMW 2209
TLLFQLCTFT+STNSRIRASLPTTIAKNSVKSVAKLCLD INYVKSPKFSKLFTIAMW
Sbjct 2156 ITLLFQLCTFTRSTNSRIRASLPTTIAKNSVKSVAKLCLDVCINYVKSPKFSKLFTIAMW 2215
Query 2210 LLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICL 2269
LLLLSICLGSLI VTAAFGVLLSN G PSYC+GVRE Y+NSSNVTTMDFCEGSF CS+CL
Sbjct 2216 LLLLSICLGSLIYVTAAFGVLLSNLGIPSYCDGVRESYVNSSNVTTMDFCEGSFLCSVCL 2275
Query 2270 SGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFG 2329
+GLDSLDSYPALETIQVTISSYKLDLT LGLAAEW LAYMLFTKFFYLLGLSAIMQVFFG
Sbjct 2276 NGLDSLDSYPALETIQVTISSYKLDLTSLGLAAEWFLAYMLFTKFFYLLGLSAIMQVFFG 2335
Query 2330 YFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMC 2389
YFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFA YY+WKSYVHIMDGCTSSTCMMC
Sbjct 2336 YFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFAFCYYVWKSYVHIMDGCTSSTCMMC 2395
Query 2390 YKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARD 2449
YKRNRATRVECTTIVNGMKRSFYVYANGGRGFCK HNWNCLNCDTFC GSTFISDEVARD
Sbjct 2396 YKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKAHNWNCLNCDTFCAGSTFISDEVARD 2455
Query 2450 LSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNT 2509
LSLQFKRPINPTDQSSY+VDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNT
Sbjct 2456 LSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNT 2515
Query 2510 KGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFD 2569
KGSLPINVIVFDGKSKCDESA+KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFD
Sbjct 2516 KGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFD 2575
Query 2570 AYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVI 2629
AYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVI
Sbjct 2576 AYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVI 2635
Query 2630 ECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLI 2689
ECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLI
Sbjct 2636 ECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLI 2695
Query 2690 WNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKL 2749
WNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVN ITTKISLKGGKIVST FKL
Sbjct 2696 WNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNAITTKISLKGGKIVSTWFKL 2755
Query 2750 MLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHA 2809
MLKATLLCVLAAL CYI+MPVH+LS+HDGYTNEIIGYKAIQDGVTRDI++TDDCFANKHA
Sbjct 2756 MLKATLLCVLAALFCYIIMPVHSLSVHDGYTNEIIGYKAIQDGVTRDIMATDDCFANKHA 2815
Query 2810 GFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAV 2869
GFD+WFSQRGGSY+NDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAV
Sbjct 2816 GFDSWFSQRGGSYRNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAV 2875
Query 2870 GNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDT 2929
GNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDT
Sbjct 2876 GNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDT 2935
Query 2930 RYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYR 2989
RYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE G+CLSTSGRWVLNNEHYR
Sbjct 2936 RYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEAGVCLSTSGRWVLNNEHYR 2995
Query 2990 ALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFG 3049
AL GVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRR FG
Sbjct 2996 ALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRAFG 3055
Query 3050 EYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMF 3109
EYNHVVAANALLFLMSFTILCL PAYSFLPGVYS+FYLYLTFYFTNDVSFLAHLQWFAMF
Sbjct 3056 EYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYLYLTFYFTNDVSFLAHLQWFAMF 3115
Query 3110 SPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLK 3169
SPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLK
Sbjct 3116 SPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLK 3175
Query 3170 LRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQP 3229
LRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQP
Sbjct 3176 LRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQP 3235
Query 3230 PQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDM 3289
PQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDM
Sbjct 3236 PQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDM 3295
Query 3290 LNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPG 3349
LNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPG
Sbjct 3296 LNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPG 3355
Query 3350 QTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT 3409
QTFSVLACYNGSPSGVYQCAMRPN+TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT
Sbjct 3356 QTFSVLACYNGSPSGVYQCAMRPNYTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT 3415
Query 3410 GVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLND 3469
GVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLND
Sbjct 3416 GVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLND 3475
Query 3470 FNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILED 3529
FNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILED
Sbjct 3476 FNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILED 3535
Query 3530 EFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFL 3589
EFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFL
Sbjct 3536 EFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFL 3595
Query 3590 PFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADT 3649
PFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADT
Sbjct 3596 PFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADT 3655
Query 3650 SLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAIS 3709
SLSGYRLKDCVMYASALVLL+LMTARTVYDDAARRVWTLMNVITLVYKVYYGN+LDQAIS
Sbjct 3656 SLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAIS 3715
Query 3710 MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC 3769
MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC
Sbjct 3716 MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC 3775
Query 3770 YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC 3829
YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC
Sbjct 3776 YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC 3835
Query 3830 IKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMV 3889
IKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMV
Sbjct 3836 IKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMV 3895
Query 3890 SLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
SLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD
Sbjct 3896 SLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3955
Query 3950 SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTM 4009
SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTM
Sbjct 3956 SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTM 4015
Query 4010 LFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYA 4069
LFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYA
Sbjct 4016 LFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYA 4075
Query 4070 SALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQM 4129
SALWEIQQVVDADSKIVQLSEINMDNS NLAWPLIVTALRANSAVKLQNNELSPVALRQM
Sbjct 4076 SALWEIQQVVDADSKIVQLSEINMDNSQNLAWPLIVTALRANSAVKLQNNELSPVALRQM 4135
Query 4130 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4189
SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP
Sbjct 4136 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4195
Query 4190 CRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAF 4249
CRFVTDTP+GPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANS VLSFCAF
Sbjct 4196 CRFVTDTPRGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSAVLSFCAF 4255
Query 4250 AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC 4309
AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC
Sbjct 4256 AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC 4315
Query 4310 HIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQ 4369
HIDHPNPKGFCDLKGKYVQIP TCANDPVGFTL+NTVCTVCG WKGYGCSCDQLREP+MQ
Sbjct 4316 HIDHPNPKGFCDLKGKYVQIPATCANDPVGFTLKNTVCTVCGTWKGYGCSCDQLREPMMQ 4375
Query 4370 SADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKD 4429
SADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNE+VAGFAKFLKTNCCRFQEKD
Sbjct 4376 SADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNERVAGFAKFLKTNCCRFQEKD 4435
Query 4430 EEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLT 4489
EEGNLLDSYFVVKRHTMSNYQHEETIYNLVK+CPAVAVHDFFKFRVDGDMVPHISRQRLT
Sbjct 4436 EEGNLLDSYFVVKRHTMSNYQHEETIYNLVKECPAVAVHDFFKFRVDGDMVPHISRQRLT 4495
Query 4490 KYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGE 4549
KYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGE
Sbjct 4496 KYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGE 4555
Query 4550 RVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSL 4609
RVRQ+LLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSL
Sbjct 4556 RVRQALLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSL 4615
Query 4610 LMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCIN 4669
LMPILTLT+ALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCIN
Sbjct 4616 LMPILTLTKALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCIN 4675
Query 4670 CLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVN 4729
CLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVN
Sbjct 4676 CLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVN 4735
Query 4730 LHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFY 4789
LHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFY
Sbjct 4736 LHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFY 4795
Query 4790 DFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF 4849
DFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF
Sbjct 4796 DFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF 4855
Query 4850 DCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTIT 4909
DCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQD LFAYTKRNVIPTIT
Sbjct 4856 DCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDVLFAYTKRNVIPTIT 4915
Query 4910 QMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHN 4969
QMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHN
Sbjct 4916 QMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHN 4975
Query 4970 MLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECA 5029
MLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKH+TCCNLSHRFYRLANECA
Sbjct 4976 MLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHSTCCNLSHRFYRLANECA 5035
Query 5030 QVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV 5089
QVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV
Sbjct 5036 QVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV 5095
Query 5090 RNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIK 5149
RNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIK
Sbjct 5096 RNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIK 5155
Query 5150 NFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGA 5209
NFKAV YYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGA
Sbjct 5156 NFKAVHYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGA 5215
Query 5210 GCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHML 5269
GCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHML
Sbjct 5216 GCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHML 5275
Query 5270 DMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCK 5329
DMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCK
Sbjct 5276 DMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCK 5335
Query 5330 CCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQ 5389
CCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCK HKPPISFPLCANGQ
Sbjct 5336 CCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKLHKPPISFPLCANGQ 5395
Query 5390 VFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLS 5449
VFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLS
Sbjct 5396 VFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLS 5455
Query 5450 YGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDA 5509
YGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDA
Sbjct 5456 YGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDA 5515
Query 5510 VVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVAN 5569
VVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVAN
Sbjct 5516 VVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVAN 5575
Query 5570 YQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID 5629
YQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID
Sbjct 5576 YQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID 5635
Query 5630 KCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVN 5689
KCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVN
Sbjct 5636 KCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVN 5695
Query 5690 ARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEI 5749
ARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEI
Sbjct 5696 ARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEI 5755
Query 5750 VDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRK 5809
VDTVSALVYDNKLKAHK+KSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRK
Sbjct 5756 VDTVSALVYDNKLKAHKEKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRK 5815
Query 5810 AVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRA 5869
AVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRA
Sbjct 5816 AVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRA 5875
Query 5870 KIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHL 5929
KIGILCIMSDRDLYDKLQFTSLE+PRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHL
Sbjct 5876 KIGILCIMSDRDLYDKLQFTSLEVPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHL 5935
Query 5930 SVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWI 5989
SVD KFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWI
Sbjct 5936 SVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWI 5995
Query 5990 GFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFK 6049
GFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFK
Sbjct 5996 GFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFK 6055
Query 6050 HLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTC 6109
HLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTC
Sbjct 6056 HLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTC 6115
Query 6110 CLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNA 6169
CLCD+RATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNA
Sbjct 6116 CLCDRRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNA 6175
Query 6170 HVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFP 6229
HVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDEL++N+ACRKVQHMVVKSALLADKF
Sbjct 6176 HVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELKINAACRKVQHMVVKSALLADKFS 6235
Query 6230 VLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNC 6289
VLHDIGNPKAIKCVPQAEV+WKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNC
Sbjct 6236 VLHDIGNPKAIKCVPQAEVDWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNC 6295
Query 6290 NVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYY 6349
NVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFT LKQLPFFYY
Sbjct 6296 NVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTYLKQLPFFYY 6355
Query 6350 SDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFS 6409
SDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCR HANEYRQYLDAYNMMISAGFS
Sbjct 6356 SDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRRHANEYRQYLDAYNMMISAGFS 6415
Query 6410 LWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDV 6469
LWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDG GEAPVSIINNAVYTKVDG DV
Sbjct 6416 LWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGQIGEAPVSIINNAVYTKVDGNDV 6475
Query 6470 EIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIG 6529
EIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIG
Sbjct 6476 EIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIG 6535
Query 6530 VCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQA 6589
VCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQA
Sbjct 6536 VCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQA 6595
Query 6590 SVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDE 6649
SVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRS+METDFLELAMDE
Sbjct 6596 SVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSKMETDFLELAMDE 6655
Query 6650 FIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFI 6709
FIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIP DSTVKNYFI
Sbjct 6656 FIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPTDSTVKNYFI 6715
Query 6710 TDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVET 6769
TDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVET
Sbjct 6716 TDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVET 6775
Query 6770 FYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYL 6829
FYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYL
Sbjct 6776 FYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYL 6835
Query 6830 NTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGD 6889
NTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTG LLVDSDLNDFVSDADSTLIGD
Sbjct 6836 NTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGALLVDSDLNDFVSDADSTLIGD 6895
Query 6890 CATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEH 6949
CATVHTANKWDLIISDMYDP+TKHVTKENDSKEGFFTYLCGFIKQKLALGGS+AVKITEH
Sbjct 6896 CATVHTANKWDLIISDMYDPKTKHVTKENDSKEGFFTYLCGFIKQKLALGGSVAVKITEH 6955
Query 6950 SWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNT 7009
SWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIG NYLGK +EQIDGYTMHANYIFWRNT
Sbjct 6956 SWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGVNYLGKLREQIDGYTMHANYIFWRNT 7015
Query 7010 NPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDI 7069
NPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLE GRLIIRENNRVVVSSDI
Sbjct 7016 NPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLENGRLIIRENNRVVVSSDI 7075
Query 7070 LVNN 7073
LVNN
Sbjct 7076 LVNN 7079
>sp|P0C6W2|R1AB_BCHK3 Replicase polyprotein 1ab OS=Bat coronavirus
HKU3 OX=442736 GN=rep PE=3 SV=1
Length=7067
Score = 10697 bits (27759), Expect = 0.0, Method: Composition-based stats.
Identities = 6765/7074 (96%), Positives = 6936/7074 (98%), Gaps = 8/7074 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDALSTNHGHKVVELVAE+DGIQ+GRSGITLGVLVPHVGETPIAYRN
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAELDGIQFGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHS+GIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
VTRYVDNNFCGPDGYPL+CIKDFLARAGKSMCTLSEQLDYIESKRGVYCCR+HEHEI W
Sbjct 181 VVTRYVDNNFCGPDGYPLECIKDFLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERS+KSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSEKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVA+PQECN+MHLSTLMKCNHCDEVSWQTCDFLKATCE CGTENLV EGPTTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
PTNAVVKMPCPACQDPE+GPEHSVADYHNHSNIETRLRKGGRT+CFGGCVF+YVGCYNKR
Sbjct 361 PTNAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFSYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASA+IG+ HTGITG+NVETLNEDLLEIL+RERVNINIVGDF NEEVAIILASF
Sbjct 421 AYWVPRASANIGANHTGITGENVETLNEDLLEILNRERVNINIVGDFRFNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SAS SAFI+T+K LDYKSFK IVESCGNYKVT GKPV GAWNIGQQRS+LTPLCGFPSQA
Sbjct 481 SASPSAFIETVKGLDYKSFKVIVESCGNYKVTNGKPVTGAWNIGQQRSILTPLCGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIF+RTLDAANHSI DLQRAAVT LDGISEQSLRLVDAMVYTSDLLTNSV++MAY
Sbjct 541 AGVIRSIFSRTLDAANHSILDLQRAAVTTLDGISEQSLRLVDAMVYTSDLLTNSVVVMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQT QWLSN+LGT V+KL+P+F W+EAKLSAGVEFL+DAWEILKFLITGVFD++
Sbjct 601 VTGGLVQQTMQWLSNMLGTAVDKLKPVFTWVEAKLSAGVEFLRDAWEILKFLITGVFDVI 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVA+DNIK+CVK F+ VVNKALEMC+DQVTIAG KLR+LNLGEVFIAQS+GLYRQC
Sbjct 661 KGQIQVATDNIKECVKIFLGVVNKALEMCLDQVTIAGTKLRALNLGEVFIAQSRGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPLKAPKEVTFLEGD+HDTVLTSEEVVLK+GELEALETP+DSFT+GA+VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDAHDTVLTSEEVVLKSGELEALETPIDSFTSGAVVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVC+NGLMLLE+++KEQYCALSPGLLATNNVFRLKGGAP+KGVTFGEDTV EVQGYKNV
Sbjct 781 TPVCINGLMLLELENKEQYCALSPGLLATNNVFRLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
+ITFELD RVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLT MGIDLDE
Sbjct 841 KITFELDVRVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTPMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
WSVATFYLFDDAGEE SSRMYCSFYPP +E++ E E+ +ETCEHEYGTEDDY+GL
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPP---DEEEDCEECEDEEETCEHEYGTEDDYKGL 957
Query 961 PLEFGASAETVRVEEEEEE-DWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
PLEFGAS ET VEEEEEE DWLDD E PVNQF GYLKLTDNVAIK
Sbjct 958 PLEFGASTETPHVEEEEEEEDWLDDAIEAEPEPEPLPEE---PVNQFVGYLKLTDNVAIK 1014
Query 1020 CVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGG 1079
C+DIVKEAQSA P VIVNAAN HLKHGGGVAGALNKATNGAMQ ESD+YI+ NGPLTVGG
Sbjct 1015 CIDIVKEAQSAKPTVIVNAANTHLKHGGGVAGALNKATNGAMQNESDEYIRQNGPLTVGG 1074
Query 1080 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1139
SCLLSGHNLA+KCLHVVGPNLNAGED+QLLK AYENFNSQD+LLAPLLSAGIFGAKPLQS
Sbjct 1075 SCLLSGHNLAEKCLHVVGPNLNAGEDVQLLKRAYENFNSQDVLLAPLLSAGIFGAKPLQS 1134
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQ 1199
L++CV+ VRTQVY+AVNDK+LY+Q+V+DYLD+LKP+VE+P +EE P E+ K + V +
Sbjct 1135 LKMCVEIVRTQVYLAVNDKSLYDQIVLDYLDSLKPKVESPNKEEEPKLEEPKA-VQPVAE 1193
Query 1200 KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDA 1259
KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLY DSQNMLRGEDMSFLEKDA
Sbjct 1194 KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYQDSQNMLRGEDMSFLEKDA 1253
Query 1260 PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAK 1319
PY+VGDVITSGDITCV+IP+KK+GGTTEML+RALK+VPV EYITTYPGQGCAGYTLEEAK
Sbjct 1254 PYIVGDVITSGDITCVIIPAKKSGGTTEMLARALKEVPVAEYITTYPGQGCAGYTLEEAK 1313
Query 1320 TALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQ 1379
TALKKCKSAFYVLPSE PN KEE+LGTVSWNLREMLAHAEETRKLMPIC+DVRAIMATIQ
Sbjct 1314 TALKKCKSAFYVLPSETPNEKEEVLGTVSWNLREMLAHAEETRKLMPICLDVRAIMATIQ 1373
Query 1380 RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA 1439
RKYKGIK+QEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHG NLEEAA
Sbjct 1374 RKYKGIKVQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGLNLEEAA 1433
Query 1440 RCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTEL 1499
RCMRSLKAPAVVSVSSPDAVT YNGYLTSSSKT EE+FVET SLAGSYRDWSYSGQRTEL
Sbjct 1434 RCMRSLKAPAVVSVSSPDAVTAYNGYLTSSSKTPEEYFVETTSLAGSYRDWSYSGQRTEL 1493
Query 1500 GVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQ 1559
GVEFLKRGDKIVYHT SP+EFHLDGEVL LDKLKSLLSLREVKTIKVFTTVDNTNLHT
Sbjct 1494 GVEFLKRGDKIVYHTTGSPIEFHLDGEVLPLDKLKSLLSLREVKTIKVFTTVDNTNLHTH 1553
Query 1560 LVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF 1619
+VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHT+DESF
Sbjct 1554 IVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTIDESF 1613
Query 1620 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRA 1679
LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ+EVKFNAPALQEAYYRA
Sbjct 1614 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQVEVKFNAPALQEAYYRA 1673
Query 1680 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1739
RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL
Sbjct 1674 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1733
Query 1740 TGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL 1799
GVEAVMYMGTLSYD LKTGVSIPCVCGR+ATQYLVQQESSFVMMSAPPAEYKLQQG FL
Sbjct 1734 KGVEAVMYMGTLSYDELKTGVSIPCVCGRNATQYLVQQESSFVMMSAPPAEYKLQQGAFL 1793
Query 1800 CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY 1859
CANEYTGNYQCGHYTHITAKETLYR+DGAHLTKMSEYKGPVTDVFYKETSYTT IKPVSY
Sbjct 1794 CANEYTGNYQCGHYTHITAKETLYRVDGAHLTKMSEYKGPVTDVFYKETSYTTAIKPVSY 1853
Query 1860 KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLN 1919
KLDGVTYTEIEPKLDGYYKK NAYYTEQPIDLVPTQP+PNASFDNFKLTCSNTKFADDLN
Sbjct 1854 KLDGVTYTEIEPKLDGYYKKGNAYYTEQPIDLVPTQPMPNASFDNFKLTCSNTKFADDLN 1913
Query 1920 QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT 1979
QMTGF KPASREL+VTFFPDLNGDVVAIDYRHYS SFKKGAKL+HKPI+WHINQ T KTT
Sbjct 1914 QMTGFKKPASRELTVTFFPDLNGDVVAIDYRHYSTSFKKGAKLVHKPILWHINQTTNKTT 1973
Query 1980 FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVI 2039
+KPN WCLRCLWSTKPVDTSNSFEVL VEDTQGMDNLACESQ TSEEVVENPT+QKE+I
Sbjct 1974 YKPNIWCLRCLWSTKPVDTSNSFEVLVVEDTQGMDNLACESQTTTSEEVVENPTVQKEII 2033
Query 2040 ECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTI 2099
ECDVKTTEVVGNVILKPS+EGVKVTQELGHEDLMAAYVE TSITIKKPNELSLALGLKT+
Sbjct 2034 ECDVKTTEVVGNVILKPSEEGVKVTQELGHEDLMAAYVEETSITIKKPNELSLALGLKTL 2093
Query 2100 ATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTF 2159
ATHG AAINSVPWSKILAYVKPFLGQ A+ TSNC K+ QRVF+NYMPYV TLLFQLCTF
Sbjct 2094 ATHGAAAINSVPWSKILAYVKPFLGQTAVITSNCIKKCVQRVFSNYMPYVITLLFQLCTF 2153
Query 2160 TKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS 2219
TKSTNSRI+ASLPTTIAKNSVKSVAKLCLD INYVKSPKFSKLFTI MWLLLLSICLGS
Sbjct 2154 TKSTNSRIKASLPTTIAKNSVKSVAKLCLDVCINYVKSPKFSKLFTIVMWLLLLSICLGS 2213
Query 2220 LICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYP 2279
L VTA GV LS+ G PSYC+GVRELY+NSSNVTTMDFC+G FPCS+CLSGLDSLDSYP
Sbjct 2214 LTYVTAVLGVCLSSLGVPSYCDGVRELYINSSNVTTMDFCQGYFPCSVCLSGLDSLDSYP 2273
Query 2280 ALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2339
ALETIQVTISSYKLDLT LGLAAEW+LAYMLFTKFFYLLGLSAIMQ FFGYFASHFISNS
Sbjct 2274 ALETIQVTISSYKLDLTFLGLAAEWLLAYMLFTKFFYLLGLSAIMQAFFGYFASHFISNS 2333
Query 2340 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2399
WLMWFIISIVQMAPVSAMVRMYIFFASFYY+WKSYVHIMDGCTSSTCMMCYKRNRATRVE
Sbjct 2334 WLMWFIISIVQMAPVSAMVRMYIFFASFYYVWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2393
Query 2400 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPIN 2459
CTTIVNG+KRSFYVYANGGRGFCK HNWNCLNCDTFC GSTFISDEVARDLSLQFKRPIN
Sbjct 2394 CTTIVNGVKRSFYVYANGGRGFCKAHNWNCLNCDTFCAGSTFISDEVARDLSLQFKRPIN 2453
Query 2460 PTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2519
PTDQS+Y+VDSV VKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV
Sbjct 2454 PTDQSAYVVDSVTVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2513
Query 2520 FDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2579
FDGKSKC+ESA+KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF
Sbjct 2514 FDGKSKCEESAAKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2573
Query 2580 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD 2639
SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD
Sbjct 2574 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD 2633
Query 2640 LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLS 2699
+EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSL+WNVKDYMSLS
Sbjct 2634 IEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLVWNVKDYMSLS 2693
Query 2700 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVL 2759
EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGK+VST FKL+LK TLLCVL
Sbjct 2694 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKVVSTWFKLLLKVTLLCVL 2753
Query 2760 AALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRG 2819
AAL CY++MPVH+LS+HDGYTNEIIGYKAIQDGVTRDI+STDDCFANKHAGFD+WFSQRG
Sbjct 2754 AALFCYVIMPVHSLSVHDGYTNEIIGYKAIQDGVTRDIVSTDDCFANKHAGFDSWFSQRG 2813
Query 2820 GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
GSY+NDK+CPVVAAIITREIGFIVPGLPGTVLRA+NGDFLHFLPRVFSAVGNICYTPSKL
Sbjct 2814 GSYRNDKNCPVVAAIITREIGFIVPGLPGTVLRALNGDFLHFLPRVFSAVGNICYTPSKL 2873
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2939
IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII
Sbjct 2874 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2933
Query 2940 QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVD 2999
QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVG+CLSTSGRWVLNNEHYRAL GVFCGVD
Sbjct 2934 QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGVCLSTSGRWVLNNEHYRALPGVFCGVD 2993
Query 3000 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANA 3059
AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRR FGEYNHVVAANA
Sbjct 2994 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRAFGEYNHVVAANA 3053
Query 3060 LLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3119
LLFLMSFTILCL PAYSFLPGVYS+FYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA
Sbjct 3054 LLFLMSFTILCLAPAYSFLPGVYSIFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3113
Query 3120 IYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3179
IYVFCISLKH HWFF+NYL+KRVMFNGVTFSTFEEAALCTFLLNKEMYL+LRSETLLPLT
Sbjct 3114 IYVFCISLKHFHWFFSNYLKKRVMFNGVTFSTFEEAALCTFLLNKEMYLRLRSETLLPLT 3173
Query 3180 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3239
QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL
Sbjct 3174 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3233
Query 3240 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI 3299
QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHV+CTAEDMLNPNY+DLLI
Sbjct 3234 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVVCTAEDMLNPNYDDLLI 3293
Query 3300 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3359
RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN
Sbjct 3294 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3353
Query 3360 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3419
GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3354 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3413
Query 3420 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3479
KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY
Sbjct 3414 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3473
Query 3480 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3539
EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ
Sbjct 3474 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3533
Query 3540 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIA 3599
CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPF LGIMA+A
Sbjct 3534 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFALGIMAVA 3593
Query 3600 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3659
ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC
Sbjct 3594 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3653
Query 3660 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3719
VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGN+LDQAISMWALVISVTS
Sbjct 3654 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAISMWALVISVTS 3713
Query 3720 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3779
NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR
Sbjct 3714 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3773
Query 3780 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3839
YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM
Sbjct 3774 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3833
Query 3840 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3899
SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ
Sbjct 3834 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3893
Query 3900 GAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3959
GAVDIN+LCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAV+NGDSEVVLKKLKK
Sbjct 3894 GAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVSNGDSEVVLKKLKK 3953
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
SLNVAKSEFD DAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN
Sbjct 3954 SLNVAKSEFDHDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4013
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV
Sbjct 4014 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4073
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4139
DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA
Sbjct 4074 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4133
Query 4140 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4199
CTDDNALAYYNN+KGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG
Sbjct 4134 CTDDNALAYYNNAKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4193
Query 4200 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4259
PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD
Sbjct 4194 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4253
Query 4260 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4319
YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF
Sbjct 4254 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4313
Query 4320 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP+MQSADASTFLNR
Sbjct 4314 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPMMQSADASTFLNR 4373
Query 4380 VCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF 4439
VCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF
Sbjct 4374 VCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF 4433
Query 4440 VVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA 4499
VVKRHTMSNYQHEETIYNL+K+CPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA
Sbjct 4434 VVKRHTMSNYQHEETIYNLIKECPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA 4493
Query 4500 LRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTV 4559
LRHFDEGNCDTLKEILVTYNCCDD+YFNKKDWYDFVENPD+LRVYANLGERVR++LLKTV
Sbjct 4494 LRHFDEGNCDTLKEILVTYNCCDDNYFNKKDWYDFVENPDVLRVYANLGERVRRALLKTV 4553
Query 4560 QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRA 4619
QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLT+A
Sbjct 4554 QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTKA 4613
Query 4620 LAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHC 4679
LAAESHMDADLAKPL+KWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHC
Sbjct 4614 LAAESHMDADLAKPLVKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHC 4673
Query 4680 ANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKE 4739
ANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKE
Sbjct 4674 ANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKE 4733
Query 4740 LLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFK 4799
LLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFK
Sbjct 4734 LLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFK 4793
Query 4800 EGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA 4859
EGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA
Sbjct 4794 EGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA 4853
Query 4860 NQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISA 4919
NQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISA
Sbjct 4854 NQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISA 4913
Query 4920 KNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE 4979
KNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE
Sbjct 4914 KNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE 4973
Query 4980 TPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCG 5039
+PHLMGWDYPKCDRAMPNMLRIMASL+LARKH+TCCNLSHRFYRLANECAQVLSEMVMCG
Sbjct 4974 SPHLMGWDYPKCDRAMPNMLRIMASLILARKHSTCCNLSHRFYRLANECAQVLSEMVMCG 5033
Query 5040 GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYEC 5099
GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYEC
Sbjct 5034 GSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYEC 5093
Query 5100 LYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQN 5159
LYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQN
Sbjct 5094 LYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQN 5153
Query 5160 NVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKT 5219
NVFMSEAKCWTETDLT+GPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKT
Sbjct 5154 NVFMSEAKCWTETDLTRGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKT 5213
Query 5220 DGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTND 5279
DGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTND
Sbjct 5214 DGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTND 5273
Query 5280 NTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTS 5339
NTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTS
Sbjct 5274 NTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTS 5333
Query 5340 HKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCV 5399
HKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCV
Sbjct 5334 HKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCV 5393
Query 5400 GSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVL 5459
GSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVL
Sbjct 5394 GSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVL 5453
Query 5460 SDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYK 5519
SDREL+LSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYK
Sbjct 5454 SDRELYLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYK 5513
Query 5520 LNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYS 5579
LNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNIS+EFSSNVANYQK+GMQKYS
Sbjct 5514 LNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISNEFSSNVANYQKIGMQKYS 5573
Query 5580 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA 5639
TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA
Sbjct 5574 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA 5633
Query 5640 RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY 5699
RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY
Sbjct 5634 RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY 5693
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD
Sbjct 5694 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5753
Query 5760 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5819
NKLKAHK+KSAQCFKM+YKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ
Sbjct 5754 NKLKAHKEKSAQCFKMYYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5813
Query 5820 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD 5879
NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD
Sbjct 5814 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD 5873
Query 5880 RDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEG 5939
RDLYDKLQFTSLE+PRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVD KFKTEG
Sbjct 5874 RDLYDKLQFTSLEVPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDTKFKTEG 5933
Query 5940 LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHAT 5999
LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHAT
Sbjct 5934 LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHAT 5993
Query 6000 RDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGL 6059
RDAVGTNLPLQLGFSTGVNLVAVPTGYVDTEN+TEFTRVNAKPPPGDQFKHLIPLMYKGL
Sbjct 5994 RDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENSTEFTRVNAKPPPGDQFKHLIPLMYKGL 6053
Query 6060 PWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCF 6119
PWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCF
Sbjct 6054 PWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCF 6113
Query 6120 STSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMT 6179
STSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMT
Sbjct 6114 STSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMT 6173
Query 6180 RCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKA 6239
RCLAVHECFVKRVDWSVEYPIIGDEL++N+ACRKVQHMVVKSALLADKF VLHDIGNPKA
Sbjct 6174 RCLAVHECFVKRVDWSVEYPIIGDELKINAACRKVQHMVVKSALLADKFTVLHDIGNPKA 6233
Query 6240 IKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAI 6299
I+CVPQAEV+WKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAI
Sbjct 6234 IRCVPQAEVDWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAI 6293
Query 6300 VCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGK 6359
VCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFT+LKQLPFFYYSDSPCESHGK
Sbjct 6294 VCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTHLKQLPFFYYSDSPCESHGK 6353
Query 6360 QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTY 6419
QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTY
Sbjct 6354 QVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTY 6413
Query 6420 NLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLP 6479
NLWNTFT+LQSLENVAYNVVNKGHFDG +GEAPVSIINNAVYTKVDGIDVEIFENKTTLP
Sbjct 6414 NLWNTFTKLQSLENVAYNVVNKGHFDGQSGEAPVSIINNAVYTKVDGIDVEIFENKTTLP 6473
Query 6480 VNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKK 6539
VNVAFELWAKRNIKPVPEIKILNNLGVDIAAN VIWDYKREAPAHVSTIGVCTMTDIAKK
Sbjct 6474 VNVAFELWAKRNIKPVPEIKILNNLGVDIAANNVIWDYKREAPAHVSTIGVCTMTDIAKK 6533
Query 6540 PTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGE 6599
PTESACSSL VLFDGRVEGQVD FRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGE
Sbjct 6534 PTESACSSLIVLFDGRVEGQVDFFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGE 6593
Query 6600 SVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGY 6659
SVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGY
Sbjct 6594 SVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGY 6653
Query 6660 AFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKC 6719
AFEHIVYGDFSHGQLGGLHLMIGLAKRSQDS LKLEDFIPMDSTVKNYFITDAQTGSSKC
Sbjct 6654 AFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSLLKLEDFIPMDSTVKNYFITDAQTGSSKC 6713
Query 6720 VCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQA 6779
VCSVIDLLLDDFVEIIKSQDLSV+SKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQA
Sbjct 6714 VCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQA 6773
Query 6780 WQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYN 6839
WQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYN
Sbjct 6774 WQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYN 6833
Query 6840 MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW 6899
MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW
Sbjct 6834 MRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKW 6893
Query 6900 DLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLM 6959
DLIISDMYDP+TKHV K+NDSKEGFFTYLCGFIKQKLALGGS+AVKITEHSWNADLYKLM
Sbjct 6894 DLIISDMYDPKTKHVLKDNDSKEGFFTYLCGFIKQKLALGGSVAVKITEHSWNADLYKLM 6953
Query 6960 GHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSL 7019
GHFSWWTAFVTNVNASSSEAFLIG NYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSL
Sbjct 6954 GHFSWWTAFVTNVNASSSEAFLIGVNYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSL 7013
Query 7020 FDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
FDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN
Sbjct 7014 FDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7067
>sp|P0DTD1|R1AB_SARS2 Replicase polyprotein 1ab OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 GN=rep PE=1
SV=1
Length=7096
Score = 10430 bits (27067), Expect = 0.0, Method: Composition-based stats.
Identities = 6122/7103 (86%), Positives = 6596/7103 (93%), Gaps = 37/7103 (1%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDA + HGH +VELVAE++GIQYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGK+ CTLSEQLD+I++KRGVYCCR+HEHEIAW
Sbjct 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVASP ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
P NAVVK+ CPAC + E+GPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+Q+S+L+PL F S+A
Sbjct 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
A V+RSIF+RTL+ A +S+ LQ+AA+TILDGIS+ SLRL+DAM++TSDL TN++++MAY
Sbjct 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
+TGG+VQ TSQWL+N+ GT EKL+P+ +W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVC+NGLMLLEIKD E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV EVQGYK+V
Sbjct 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
WS+AT+YLFD++GE +S MYCSFYPPDE+EE+ EEE T ++EYGTEDDYQG
Sbjct 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPST-QYEYGTEDDYQGK 958
Query 961 PLEFGASAETVRVEEEEEEDWLDDTTEQ-------------------SEIEP--EPEPTP 999
PLEFGA++ ++ EEE+EEDWLDD ++Q E++P E E TP
Sbjct 959 PLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
Query 1000 ---EEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKA 1056
VN F+GYLKLTDNV IK DIV+EA+ P V+VNAAN++LKHGGGVAGALNKA
Sbjct 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
Query 1057 TNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF 1116
TN AMQ ESDDYI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYENF
Sbjct 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
Query 1117 NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPR- 1175
N ++LLAPLLSAGIFGA P+ SL+VCV TVRT VY+AV DK LY+++V +L+ +
Sbjct 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
Query 1176 -----VEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLL 1230
E PK+E P +SK SV Q+ D K KIKAC++EVTTTLEETKFLT LL
Sbjct 1199 VEQKIAEIPKEEVKPFITESK---PSVEQRKQDDK-KIKACVEEVTTTLEETKFLTENLL 1254
Query 1231 LFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLS 1290
L+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML+
Sbjct 1255 LYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLA 1314
Query 1291 RALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWN 1350
+AL+KVP D YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSWN
Sbjct 1315 KALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWN 1374
Query 1351 LREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASI 1410
LREMLAHAEETRKLMP+C++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS+
Sbjct 1375 LREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASL 1434
Query 1411 ITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSS 1470
I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSSS
Sbjct 1435 INTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS 1494
Query 1471 KTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSL 1530
KT EEHF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGEV++
Sbjct 1495 KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVITF 1553
Query 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNH 1590
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH +H
Sbjct 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSH 1613
Query 1591 EGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN 1650
EGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNN
Sbjct 1614 EGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNN 1673
Query 1651 CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMT 1710
CYL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM+
Sbjct 1674 CYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMS 1733
Query 1711 HLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDA 1770
+L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+ A
Sbjct 1734 YLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQA 1793
Query 1771 TQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHL 1830
T+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA L
Sbjct 1794 TKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALL 1853
Query 1831 TKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPID 1890
TK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPID
Sbjct 1854 TKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPID 1913
Query 1891 LVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYR 1950
LVP QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY+
Sbjct 1914 LVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYK 1973
Query 1951 HYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDT 2010
HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1974 HYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDA 2033
Query 2011 QGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHE 2070
QGMDNLACE +P SEEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+GH
Sbjct 2034 QGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHT 2093
Query 2071 DLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITT 2130
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + TT
Sbjct 2094 DLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTT 2153
Query 2131 SNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
+N R RV NYMPY FTLL QLCTFT+STNSRI+AS+PTTIAKN+VKSV K CL+A
Sbjct 2154 TNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEA 2213
Query 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNS 2250
NY+KSP FSKL I +W LLLS+CLGSLI TAA GVL+SN G PSYC G RE YLNS
Sbjct 2214 SFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNS 2273
Query 2251 SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYML 2310
+NVT +C GS PCS+CLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+L
Sbjct 2274 TNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYIL 2333
Query 2311 FTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYI 2370
FT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY+
Sbjct 2334 FTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYV 2393
Query 2371 WKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCL 2430
WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC+
Sbjct 2394 WKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCV 2453
Query 2431 NCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTY 2490
NCDTFC GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV VKNG++HLYFDKAGQKTY
Sbjct 2454 NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTY 2513
Query 2491 ERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLD 2550
ERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES++KSASVYYSQLMCQPILLLD
Sbjct 2514 ERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLD 2573
Query 2551 QALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTF 2610
QALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF
Sbjct 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
Query 2611 VSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACID 2670
+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACID
Sbjct 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACID 2693
Query 2671 CNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNV 2730
C+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV
Sbjct 2694 CSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNV 2753
Query 2731 ITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
+TTKI+LKGGKIV+ K ++K TL+ + A + Y++ PVH +S H +++EIIGYKAI
Sbjct 2754 VTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAID 2813
Query 2791 DGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTV 2850
GVTRDI STD CFANKHA FD WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT+
Sbjct 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTI 2873
Query 2851 LRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYC 2910
LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYC
Sbjct 2874 LRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC 2933
Query 2911 YDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE 2970
YDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2934 YDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
Query 2971 VGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGII 3030
G+C+STSGRWVLNN++YR+L GVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+
Sbjct 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
Query 3031 AILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLT 3090
AI+VTC AYYFM+FRR FGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYSV YLYLT
Sbjct 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
Query 3091 FYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFS 3150
FY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNGV+FS
Sbjct 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFS 3173
Query 3151 TFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCH 3210
TFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCH
Sbjct 3174 TFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCH 3233
Query 3211 LAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3270
LAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL
Sbjct 3234 LAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
Query 3271 WLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLK 3330
WLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LK
Sbjct 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
Query 3331 VDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGF 3390
VDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGF
Sbjct 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
Query 3391 NIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA 3450
NIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYA
Sbjct 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
Query 3451 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKE
Sbjct 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
Query 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLI 3570
LLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+
Sbjct 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
Query 3571 LVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMV 3630
LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMV
Sbjct 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
Query 3631 YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMN 3690
YMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMN
Sbjct 3654 YMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMN 3713
Query 3691 VITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
V+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITG
Sbjct 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
Query 3751 NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKS 3810
NTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+
Sbjct 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
Query 3811 SIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3870
SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ
Sbjct 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
Query 3871 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPS 3930
LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPS
Sbjct 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPS 3953
Query 3931 YAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 3990
YAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY
Sbjct 3954 YAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 4013
Query 3991 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4050
KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV
Sbjct 4014 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4073
Query 4051 VPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA 4110
+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRA
Sbjct 4074 IPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 4133
Query 4111 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKW 4170
NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLKW
Sbjct 4134 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKW 4193
Query 4171 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4230
ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ
Sbjct 4194 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4253
Query 4231 AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4290
AGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE
Sbjct 4254 AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
Query 4291 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 4350
ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVC
Sbjct 4314 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVC 4373
Query 4351 GMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEK 4410
GMWKGYGCSCDQLREP++QSADA +FLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYN+K
Sbjct 4374 GMWKGYGCSCDQLREPMLQSADAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDK 4433
Query 4411 VAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDF 4470
VAGFAKFLKTNCCRFQEKDE+ NL+DSYFVVKRHT SNYQHEETIYNL+KDCPAVA HDF
Sbjct 4434 VAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDF 4493
Query 4471 FKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD 4530
FKFR+DGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD
Sbjct 4494 FKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKD 4553
Query 4531 WYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGD 4590
WYDFVENPDILRVYANLGERVRQ+LLKTVQFCDAMR+AGIVGVLTLDNQDLNGNWYDFGD
Sbjct 4554 WYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGD 4613
Query 4591 FVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLC 4650
F+Q PG GVP+VDSYYSLLMPILTLTRAL AESH+D DL KP IKWDLLKYDFTEERL
Sbjct 4614 FIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLK 4673
Query 4651 LFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV 4710
LFDRYFKYWDQTYHPNC+NCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV
Sbjct 4674 LFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFV 4733
Query 4711 VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL 4770
VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL
Sbjct 4734 VSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAAL 4793
Query 4771 TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP 4830
TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP
Sbjct 4794 TNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLP 4853
Query 4831 TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY 4890
TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY
Sbjct 4854 TMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSY 4913
Query 4891 EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA 4950
EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA
Sbjct 4914 EDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAA 4973
Query 4951 TRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARK 5010
TRGATVVIGTSKFYGGWHNMLKTVYSDVE PHLMGWDYPKCDRAMPNMLRIMASLVLARK
Sbjct 4974 TRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARK 5033
Query 5011 HNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT 5070
H TCC+LSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT
Sbjct 5034 HTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVT 5093
Query 5071 ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDD 5130
ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVD +FV+EFYAYLRKHFSMMILSDD
Sbjct 5094 ANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDD 5153
Query 5131 AVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK 5190
AVVC+NS YA+QGLVASIKNFK+VLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK
Sbjct 5154 AVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVK 5213
Query 5191 QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF 5250
QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF
Sbjct 5214 QGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVF 5273
Query 5251 HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN 5310
HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN
Sbjct 5274 HLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCN 5333
Query 5311 SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS 5370
SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS
Sbjct 5334 SQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMS 5393
Query 5371 YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER 5430
YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER
Sbjct 5394 YYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTER 5453
Query 5431 LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK 5490
LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK
Sbjct 5454 LKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTK 5513
Query 5491 NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI 5550
NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI
Sbjct 5514 NSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRI 5573
Query 5551 TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC 5610
TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC
Sbjct 5574 TGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTAC 5633
Query 5611 SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD 5670
SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD
Sbjct 5634 SHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTAD 5693
Query 5671 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM 5730
IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM
Sbjct 5694 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLM 5753
Query 5731 KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN 5790
KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN
Sbjct 5754 KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAIN 5813
Query 5791 RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT 5850
RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT
Sbjct 5814 RPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQT 5873
Query 5851 TETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF 5910
TETAHSCNVNRFNVAITRAK+GILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF
Sbjct 5874 TETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLF 5933
Query 5911 KDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG 5970
KDCSK+ITGLHPTQAPTHLSVD KFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG
Sbjct 5934 KDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNG 5993
Query 5971 YPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTE 6030
YPNMFITREEAIRHVRAWIGFDVEGCHATR+AVGTNLPLQLGFSTGVNLVAVPTGYVDT
Sbjct 5994 YPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTP 6053
Query 6031 NNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAH 6090
NNT+F+RV+AKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK LSDRVVFVLWAH
Sbjct 6054 NNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAH 6113
Query 6091 GFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWG 6150
GFELTSMKYFVKIGPERTCCLCD+RATCFST+SDTYACW+HS+GFDYVYNPFMIDVQQWG
Sbjct 6114 GFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWG 6173
Query 6151 FTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSA 6210
FTGNLQSNHD +CQVHGNAHVASCDAIMTRCLAVHECFVKRVDW++EYPIIGDEL++N+A
Sbjct 6174 FTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAA 6233
Query 6211 CRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFY 6270
CRKVQHMVVK+ALLADKFPVLHDIGNPKAIKCVPQA+VEWKFYDAQPCSDKAYKIEELFY
Sbjct 6234 CRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFY 6293
Query 6271 SYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT 6330
SYATH DKFTDGVCLFWNCNVDRYPAN+IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT
Sbjct 6294 SYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHT 6353
Query 6331 PAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA 6390
PAFDKSAF NLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA
Sbjct 6354 PAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHA 6413
Query 6391 NEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGE 6450
NEYR YLDAYNMMISAGFSLW+YKQFDTYNLWNTFTRLQSLENVA+NVVNKGHFDG GE
Sbjct 6414 NEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGE 6473
Query 6451 APVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAA 6510
PVSIINN VYTKVDG+DVE+FENKTTLPVNVAFELWAKRNIKPVPE+KILNNLGVDIAA
Sbjct 6474 VPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAA 6533
Query 6511 NTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGV 6570
NTVIWDYKR+APAH+STIGVC+MTDIAKKPTE+ C+ LTV FDGRV+GQVDLFRNARNGV
Sbjct 6534 NTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGV 6593
Query 6571 LITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLE 6630
LITEGSVKGL PS GP QAS+NGVTLIGE+VKTQFNY+KKVDG++QQLPETYFTQSR+L+
Sbjct 6594 LITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQ 6653
Query 6631 DFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDS 6690
+FKPRSQME DFLELAMDEFI+RYKLEGYAFEHIVYGDFSH QLGGLHL+IGLAKR ++S
Sbjct 6654 EFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKES 6713
Query 6691 PLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVT 6750
P +LEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV+SKVVKVT
Sbjct 6714 PFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVT 6773
Query 6751 IDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAV 6810
IDY EISFMLWCKDGHVETFYPKLQ+SQAWQPGVAMPNLYKMQRMLLEKCDLQNYG++A
Sbjct 6774 IDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSAT 6833
Query 6811 IPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL 6870
+PKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL
Sbjct 6834 LPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLL 6893
Query 6871 VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCG 6930
VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDP+TK+VTKENDSKEGFFTY+CG
Sbjct 6894 VDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICG 6953
Query 6931 FIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKP 6990
FI+QKLALGGS+A+KITEHSWNADLYKLMGHF+WWTAFVTNVNASSSEAFLIG NYLGKP
Sbjct 6954 FIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKP 7013
Query 6991 KEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLL 7050
+EQIDGY MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE QINDMI SLL
Sbjct 7014 REQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLL 7073
Query 7051 EKGRLIIRENNRVVVSSDILVNN 7073
KGRLIIRENNRVV+SSD+LVNN
Sbjct 7074 SKGRLIIRENNRVVISSDVLVNN 7096
>sp|P0C6W4|R1AB_BCHK5 Replicase polyprotein 1ab OS=Bat coronavirus
HKU5 OX=694008 GN=rep PE=3 SV=1
Length=7182
Score = 9110 bits (23640), Expect = 0.0, Method: Composition-based stats.
Identities = 3323/7274 (46%), Positives = 4517/7274 (62%), Gaps = 334/7274 (5%)
Query 9 NEKT--HVQLSLPVLQVRDVLV---RGFGDSVEEALSEAREHLKNGTCGLV--ELEKGVL 61
EK HV L + D+++ F D E A E L G+ L + KG +
Sbjct 22 TEKRTDHVSLKASLCDAGDLVLKISPWFMDG-ESAYKHVSEQLSKGSKLLFVPQTLKGFI 80
Query 62 PQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITL-----GVLVPHVGETPI 116
L P V++ T +V +A + G G TL G+ P +
Sbjct 81 RHLPGPRVYLVERLTGGTYSDPFMVNQLAYQNAAGEGVIGTTLQGKRVGMFFPFDADLVT 140
Query 117 AYRNVLLRKNGNKGAGGHSYGIDLKSY------DLGDELGTDPIEDYEQNWNTKHGSGAL 170
LLRK KG GG+ + Y DL D L DP Y Q+
Sbjct 141 GEFQFLLRK---KGFGGNRFRDAPWDYNWTPYSDLMDALEADPCGKYSQS---------- 187
Query 171 RELTRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAG--KSMCTLSEQLDYIESKRGV 228
L ++L GG T +D CG +G P+ +A G K +E +S R +
Sbjct 188 --LLKKLVGGDFTP-IDQYMCGKNGKPIAEFAALMASEGITKLADVEAEVKSRTDSDRYI 244
Query 229 YCCRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRV 288
++ + I W +R D +Y Q+ F + S + DT + + P+ F + S+++VI P
Sbjct 245 -VFKNKLYRIVWNVQRKDVAYSKQSAFTMNSIVQLDTME-DVPRHSFTIGSEIQVIAPST 302
Query 289 EKKKTEGFMGRIRSVYPVASPQ---ECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCG 345
+ + R +Y Q E N ++ S + C C + SW T + ++ CG
Sbjct 303 AVQANGHLNLKQRLLYAFYGKQAVSEPNYIYHSAYVDCTSCGKGSWLTGNAVQGFACDCG 362
Query 346 TENLVIE-GPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRT- 403
+ + G + NAV+ CP +D E +H++ + + + G+T
Sbjct 363 AHYCANDVDLQSSGLVRKNAVLLTTCPCNKDGEC--KHTLPQLVSMMTDKCDVEVVGKTF 420
Query 404 -RCFGGCVFAYVGCYNKRAYWVPRASA-------DIGSGHTGITGDNVETLNEDLLEILS 455
+GG ++AY+GC +++PRA + I +G TG ET N L
Sbjct 421 ILTYGGVIYAYMGCSGGTMHFIPRAKSCVSKIGDAIFTGCTGTWSKVCETAN----LFLE 476
Query 456 RERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGK 515
R + IN V +F L E V +L+ ++S D ++ ++ + + G + VT G
Sbjct 477 RAQHAINFVNEFVLTETVVALLSGTTSSIEELRDLCRNATFEKVRDYLTPRG-WIVTMGS 535
Query 516 PVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISE 575
++G N+G +C A ++ S + + L + LD ++
Sbjct 536 YIEGVINVGA-----AGVCNAALNAPFIVLSGLGESFKKVAATPWKLCSSLRETLDHYAD 590
Query 576 QSLRLV-------DAMVYTSDLLTNSVII--MAYVTGGLVQQTSQWLSNLLGT-TVEKLR 625
V D YT+ LL +V+ AY V + + L+NL+ + +
Sbjct 591 SITYRVFPYDIPCDVTDYTALLLDCAVLTGASAYFVARYVDEKVEQLTNLVFSSCQSAVA 650
Query 626 PIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKA 685
+ + A +F+ D + ++K + ++ V D +K F+ +++KA
Sbjct 651 AFVQACMSTYKATAKFISDMFTLIKVVSERLYVYTSVGFVVVGDYSSQLLKQFMHILSKA 710
Query 686 LEMCIDQVTIAGAKLRSL--NLGEVFIAQSKGLYRQCIRGK---EQLQLLMPLK-APKEV 739
+++ V+ AG+KL S+ N + + S Y +G+ +Q L++P + K++
Sbjct 711 MQLLHTTVSWAGSKLPSVVYNGRDSLVFPSGTYYCVSTQGRSLQDQFDLVIPGDLSKKQI 770
Query 740 TFLEGDSHDTVLTSE----EVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLE-IK 794
LE + T + + V + G+LE P + +VG V ++ + + ++
Sbjct 771 GILEPTPNSTTVDKKINTNVVEVVVGQLE----PTKEHSPELVVGDYVIISNKIFVRSVE 826
Query 795 DKE--QYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDERVDK 852
D E Y + G + +FRLKGGAP KGV FG + E+ ++V + +++ +D
Sbjct 827 DSETVFYPLCTDGKIV-PTLFRLKGGAPPKGVKFGGEQTKEITAVRSVSVDYDVHPVLDA 885
Query 853 VL-NEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDD 911
+L + + +TVE V +F VV + V++ L + G DL++++ Y+++
Sbjct 886 LLAGSELATFTVEKDLPVKDFVDVVKDEVIELLSKLLRGYNVDGFDLEDFADTPCYVYNA 945
Query 912 AGEENFSSRMYCSFYPPDEEEE--DDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAE 969
G+ +SS M S P +E EE DD E+E + E E E+D + A+ E
Sbjct 946 EGDLAWSSTMTFSVNPVEEVEEECDDDYVEDEYLSE----EMLVEEDEN----SWAAAVE 997
Query 970 TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQS 1029
V E+ + D L + SE P + V + T+ V + +++ +Q
Sbjct 998 AVIPMEDVQLDTLVAEIDVSE--------PADDVAEQAS----TEEVEVPSACVLEASQV 1045
Query 1030 ANPMVIVN-----AANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLS 1084
AN + + +++I L A A + A ++ KL+ VG
Sbjct 1046 ANAAEVESCEAEVSSSIPLHEDANAAKANDCAEGMPALDSTETVSKLSVDTPVGD----- 1100
Query 1085 GHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
V + + + + + +S+ ++ P + P ++L V
Sbjct 1101 ----------VTQDDATSSNATVISEDVHTATHSKGLVAVPEVV-------PEKALGTSV 1143
Query 1145 QTVRTQVYIAVNDKALYEQ--VVMDYLDNLKP-RVEAPKQEEPPNTEDSKTEEKSVVQKP 1201
+ +R+ V + +L ++ V++ + KP RV+ PK E P V
Sbjct 1144 ERMRSTSEWTVVETSLKQETAVIVKNDSSAKPQRVKKPKAENPLKNFKHIVLNNDVTLVF 1203
Query 1202 VDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPY 1261
D +A D + T L I + S +++ E ++ P
Sbjct 1204 GDAIAVARATEDCILVNAANTH-----LKHGGGIAAAIDRASGGLVQAESDDYVNFYGPL 1258
Query 1262 MVGDVIT------SGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTL 1315
VGD + I VV P +A ++L R K ++Y AG
Sbjct 1259 NVGDSTLLKGHGLATGILHVVGPDARANQDIQLLKRCYKAF--NKYPLVVSPLISAGIFC 1316
Query 1316 EEAKTALKKCKSA-----FYVLPSE-------APNAKEEI-LGTVSWNLREMLAHAEETR 1362
E + +L+ S + V+ SE AP + W R ++ +A+
Sbjct 1317 VEPRVSLEYLLSVVHTKTYVVVNSEKVYNDLAAPKPPTGLTYSHEGW--RGIIRNAKSFG 1374
Query 1363 KLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLV 1422
IC D A ++ + + + VD GV+++ Y+SK+P+ IIT N+ + +
Sbjct 1375 FTCFICTDQSANAKLLKGRGVDLTKKTQTVD-GVKYYLYSSKDPLTDIITAANAC-KGIC 1432
Query 1423 TMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVS 1482
MPIGYVTHG +L +A + ++ + P V ++S D V N + + +T E+ F+ TV
Sbjct 1433 AMPIGYVTHGLDLAQAGQQVKKITVPYVCLLASKDQVPILNSDV--AVQTPEQSFINTVI 1490
Query 1483 LAGSYRDWSY-SGQRTELGVEF---LKRGDKIV------YHTLESPVEFHLDGEVLSLDK 1532
G Y W +G+ GV + L D+ + ++ ++ + D SL+K
Sbjct 1491 ANGGYHCWHLVTGELIVKGVSYRKLLNWSDQTICYADNKFYVVKGQIALPFD----SLEK 1546
Query 1533 LKSLLSLR--EVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNH 1590
++ L+ R + K + V T+D N T +++ + TY Q G + G+D++ P
Sbjct 1547 CRTYLTSRAAQQKNVDVLVTIDGVNFRTVVLNNTTTYRVQLGSVFYKGSDISDTIPTEKM 1606
Query 1591 EGKTFFVLPSDDTLRSEAF-EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADN 1649
G+ ++ + E Y T D +FL RY S L KKWK+ G+ S+K N
Sbjct 1607 SGEAVYLADNLSEAEKAVLSEVYGTADTAFLHRYYSLLALVKKWKYTVHDGVKSLKLNSN 1666
Query 1650 NCYLSSVLLALQQLE-VKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRET 1708
NCY++ +L L L+ +KF PALQ AY + + GD+ F ALI+AY + T GE D
Sbjct 1667 NCYVNVTMLMLDMLKEIKFIVPALQAAYLKHKGGDSTEFIALIMAYGDCTYGEPDDASRL 1726
Query 1709 MTHLLQHANLES-AKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCG 1767
+ +L A L + AK V C CG + TT TG++A +Y+G S D L C CG
Sbjct 1727 LHTILSKAELTTQAKMVWRQWCNVCGVQDTTTTGLKACIYVGMNSLDELHATHEECCQCG 1786
Query 1768 RDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTG-------NYQCGHYTHITAKE 1820
+ LV+ + ++++S + + +YT GHY H+ K+
Sbjct 1787 DVRKRQLVEHNAPWLLLSGLNEAKVMTPTSQSAGPDYTAFNVFQGVETSVGHYLHVRVKD 1846
Query 1821 TL-YRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKK 1879
L Y+ D L+K S+ K +TDV+Y + Y+ V Y LDG T+ +++P L +Y K
Sbjct 1847 NLLYKYDSGSLSKTSDMKCKMTDVYYPKQRYSADCNVVVYSLDGNTWADVDPDLSAFYMK 1906
Query 1880 DNAYYTEQP-IDLVPTQPLPNASFDNFKLTCSNTKFADD-----LNQMTGF--TKPASRE 1931
D Y+T++P I+ P L + + N L + D N + GF +KP S++
Sbjct 1907 DGKYFTKKPVIEYSPATILSGSVYTNSCLVGHDGTIGSDAISSSFNNLLGFDNSKPVSKK 1966
Query 1932 LSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLW 1991
L+ +FFPD GDV+ +Y Y +K GA L KPI+W N K N LR ++
Sbjct 1967 LTYSFFPDFEGDVILTEYSTYDPIYKNGAMLHGKPILWVNNSKFDSALNKFNRATLRQVY 2026
Query 1992 STKPVDTSNSFEVLAVEDTQGMDNLAC-ESQQPTSE-EVVENPTIQKEVIECD-VKTTEV 2048
PV N + VL Q ++ A E +P S +V E+ + +I+C +K V
Sbjct 2027 DIAPVTLENKYTVLQDNQIQQVEVEAPKEDAKPQSPVQVAEDIDNKLPIIKCKGLKKPFV 2086
Query 2049 VGNVILKPSDEGVKVTQELGHEDLMAAYVE-NTSITIKKPNELSLALGLKTIATHG---I 2104
+GV V LG +DL A YV+ N + + K N S + T+ I
Sbjct 2087 KDGYSFVNDPQGVNVIDTLGIDDLRALYVDRNLRLIVLKENNWSALFNIHTVEKGDLSVI 2146
Query 2105 AAINSVPWS-KILAYVKPFLGQAAITTSNCAK-------RLAQRVFNN--YMPYVFTLLF 2154
AA S+ KIL Q A T N R+ + V N + F LL
Sbjct 2147 AASGSITRRVKILLGASSLFAQFASVTVNVTTAMGKALGRMTRNVITNTGIIGQGFALLK 2206
Query 2155 QL----CTFTKSTN-SRIRASLPTTIAKNSVKS-VAKLCLDAGINYVKSPKFSKLFTIAM 2208
L TF KS N S ++ + V + V K C A + V KF ++ +
Sbjct 2207 MLLILPFTFWKSKNQSTVKVEVGALRTAGIVTTNVVKQCASAAYD-VLVVKFKRIDWKST 2265
Query 2209 WLLLLSIC------------------LGSLICVTAAFGVLL------SNFGAPSYCNGVR 2244
LL IC L S + + A G+L S G S C+G+
Sbjct 2266 LRLLFLICTTGLLLSSLYYLFLFHQVLTSDVMLDGAEGMLATYRELRSYLGIHSLCDGMV 2325
Query 2245 ELYLNSSNVTTMDFCEG-SFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAE 2303
E Y N S DFC S C+ CL G DSL Y A + IQ ++SY +++ + E
Sbjct 2326 EAYRNVS-YDVNDFCSNRSALCNWCLIGQDSLTRYSAFQMIQTHVTSYVINIDWVWFVME 2384
Query 2304 WVLAYMLFTKFFYLLGLSAIMQVFFGYFAS--HFISNSWLMWFIISIVQMAPVSAMVRMY 2361
+ LAY+L+T F +L L Q FF Y + ++ S ++L+ V P+ +VR+Y
Sbjct 2385 FALAYVLYTSTFNVLLLVVSSQYFFSYTGAFVNWRSYNYLVSGYFFCVTHIPLLGLVRIY 2444
Query 2362 IFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGF 2421
F A +++ + Y H+++GC + C++CYKRNR TRVE +T+V G KR+FY+ ANGG F
Sbjct 2445 NFLACLWFLRRFYNHVINGCKDTACLLCYKRNRLTRVEASTVVCGSKRTFYIVANGGTSF 2504
Query 2422 CKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLY 2481
C HNWNC++CDT G+TFI +EVA DL+ +R + PTD+S Y V+SV VK+ + L+
Sbjct 2505 CCRHNWNCVDCDTAGIGNTFICEEVANDLTTSLRRLVKPTDKSHYYVESVTVKDSVVQLH 2564
Query 2482 FDKAGQKTYERHPLSHFVNLDNLR----ANNTKGSLPINVIVFDGKSKCDESASKSASVY 2537
+ + G YER+PL +F NLD L+ G N +++D + E+ ++SA VY
Sbjct 2565 YSREGASCYERYPLCYFTNLDKLKFKEVCKTPTGIPEHNFLIYDSSDRGQENLARSACVY 2624
Query 2538 YSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSEL 2597
YSQ++ +P+LL+D +V+ VGDS E++ KM D+YV++F + F V +KL LVATA +
Sbjct 2625 YSQVLSKPMLLVDSNMVTTVGDSREIASKMLDSYVNSFISLFGVNRDKLDKLVATARDCV 2684
Query 2598 AKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNK 2656
+G V+ TF AAR V++DV+T +++ L+ ++ DL++T + NN++ +Y K
Sbjct 2685 KRGDDFQTVIKTFTDAARGPAGVESDVETSSIVDALQYAYKHDLQLTTEGFNNYVPSYIK 2744
Query 2657 VENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIP 2716
+++ DLG ID NA +N ++ N + IWN DYM LS+ L++QIR A +K NIP
Sbjct 2745 PDSVATADLGCLIDLNAASVNQTSIRNANGACIWNSSDYMKLSDSLKRQIRIACRKCNIP 2804
Query 2717 FRLTCATTRQVVNVITTKIS---LKGGK------IVSTCFKLMLKATLLCVLAALVCYIV 2767
FRLT + R N+++ K S L GG + +K TL+ A++ Y+
Sbjct 2805 FRLTTSRLRSADNILSVKFSATKLSGGAPKWLLKLRDFTWKSYCVVTLVVFAMAVLSYLC 2864
Query 2768 MPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQR-GGSYKNDK 2826
+P +S + + I+ YK +++G+ RDI +D CFANK+ F WF++ GG + ND
Sbjct 2865 LPAFNMSQVSFHEDRILTYKVVENGIIRDITPSDTCFANKYQSFSKWFNEHYGGLFNNDI 2924
Query 2827 SCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFA 2886
SCPV A+I G VP LP V + + F+ RVF++ N+CYTP+ I Y F+
Sbjct 2925 SCPVTVAVIAGVAGARVPNLPANV-AWVGRQIVLFVSRVFASSNNVCYTPTAEIPYERFS 2983
Query 2887 TSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTY 2945
S CVLA+ECT+F+DA GK PYCYD +L G+ +Y +++P RY + D I+FP
Sbjct 2984 DSGCVLASECTLFRDAEGKINPYCYDPTVLPGASAYDQMKPHVRYDMYDSDMYIKFPEVV 3043
Query 2946 LEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIA 3005
E ++R+ T YCR G+CE + G+C++T+G W + N+HY GV+CG + +++
Sbjct 3044 FESTLRITKTLATRYCRFGSCEDANEGVCITTNGSWAIYNDHYANKPGVYCGDNYFDIVR 3103
Query 3006 NIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMS 3065
+ L QPV +S S+ G ++ I +T A YY K +R +Y L++
Sbjct 3104 RLGLSLFQPVTYFQLSTSLALGVMLCIFLTIAFYYVNKVKRALADYTQCAVVAVAAALLN 3163
Query 3066 FTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCI 3125
LC V + L Y+ Y Y TFY T + +F+ H+ WF MF +VP W+ Y+ +
Sbjct 3164 SLCLCFVVSNPLLVLPYTALYYYATFYLTGEPAFVMHVSWFVMFGTVVPIWMVFAYIVGV 3223
Query 3126 SLKHCHWFFNNYLRK--RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNR 3183
L+H W + +K V +G +F++AA F++NK+ Y+ LR+ + YNR
Sbjct 3224 CLRHLLWVMAYFSKKHVEVFTDGKLNCSFQDAAANIFVINKDTYVALRNS--ITQDSYNR 3281
Query 3184 YLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGF 3243
YL+++NKYKY+SGA+DT SYREA+ HL KAL +S +G+DVL+QPP S+TS+VLQSG
Sbjct 3282 YLSMFNKYKYYSGAMDTASYREASAAHLCKALQVYSETGSDVLFQPPNCSVTSSVLQSGL 3341
Query 3244 RKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSN 3303
KMA PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C A+ + +PNY+ LL+ K+N
Sbjct 3342 VKMAAPSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDALLVSKTN 3401
Query 3304 HSFLVQAG---NVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
SF+VQ LRV+GH+M LL+L V+++NP+TP Y F ++PG +FSVLACYNG
Sbjct 3402 LSFIVQKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFSVLACYNG 3461
Query 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
P+GV+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H G +G
Sbjct 3462 RPTGVFMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHTGCAFDGV 3521
Query 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
YG F DRQ Q +D T+N++AWLYAA++NG WF+ T + FN AM +
Sbjct 3522 MYGAFEDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEWAMSNQFT 3581
Query 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
+ L+ +TG++V + A++ L G G+TILG+++LEDEFTP DV Q
Sbjct 3582 EFIG--TQSVDMLAHKTGVSVEQLLYAIQTL-HKGFQGKTILGNSMLEDEFTPDDVNMQV 3638
Query 3541 SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA 3600
GV Q K+I G HW+ T L + + +Q T+++++ +++E L T ++ + A
Sbjct 3639 MGVVMQSGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLTPLVLCVMA 3698
Query 3601 CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPA----SWVMRIMTWLELADTSLSGYRL 3656
C ML VKHKH FL LFLLP+ + Y N+VY P S ++ + WL A +
Sbjct 3699 CVMLTVKHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPASVYMRTTH- 3757
Query 3657 KDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVIS 3716
D +Y S L ++ R +A+ L + + Y G+ ++ + +
Sbjct 3758 TDLGVYLSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPLTYLMFLTT 3816
Query 3717 VTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCL 3776
+TS+Y+ V + +A+ V Y P ++ ++L+Y +GY C YFG+F L
Sbjct 3817 LTSDYTVTVFLAVNVAKFFARVVFLYAPHAGFIFPEVKLVLLMYLAVGYFCTVYFGVFSL 3876
Query 3777 LNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3836
LN R+ LGVYDY VSTQEFRY+ GL P++S +A +LN+KL+GIGG PCIK+A+VQ
Sbjct 3877 LNLKLRVPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTPCIKIASVQ 3936
Query 3837 SKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLL 3896
SK++D+KCTSVVLLSVLQQL +E++SK WA CV+LHNDIL A D TEAF+ V L + L+
Sbjct 3937 SKLTDLKCTSVVLLSVLQQLHLEANSKAWAHCVKLHNDILAATDPTEAFDNFVCLFATLM 3996
Query 3897 SMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLK 3955
S VD+ L ++LD+ + LQA SEFS L SYA AQ +Y++A+ +GD S VLK
Sbjct 3997 SFSANVDLEALASDLLDHPSVLQATLSEFSHLASYAELEAAQSSYQKALNSGDASPQVLK 4056
Query 3956 KLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLR 4015
L+K++N+AK+ +++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++
Sbjct 4057 ALQKAVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIK 4116
Query 4016 KLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEI 4075
KLDND LN +I+NAR+GCVPL+++PL + KL VV+PD + + +YA ALW+I
Sbjct 4117 KLDNDVLNGVISNARNGCVPLSVVPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWDI 4176
Query 4076 QQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA-NSAVKLQNNELSPVALRQMSCAAG 4134
+ + D ++V+ S++ N +L WPL++ RA +SAV LQNNE+ P L+ M +AG
Sbjct 4177 SLINNVDGEVVKSSDVTETN-ESLTWPLVLECTRAASSAVTLQNNEIRPSGLKTMVVSAG 4235
Query 4135 TTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVT 4194
C + ++LAYY +G + ++ +LS++ LKWA+ DG I EL+PPC+F+
Sbjct 4236 IDHANC-NTSSLAYYEPVEGRKMLMGILSENAHLKWAKVEGRDGFVNI--ELQPPCKFLI 4292
Query 4195 DTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPA 4254
PKGP+V+YLYF+K LNNL+RG +LG +AATVRLQAG+ TE NS+VLS F+VDP
Sbjct 4293 AGPKGPEVRYLYFVKNLNNLHRGQLLGHIAATVRLQAGSNTEFAINSSVLSAVTFSVDPG 4352
Query 4255 KAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHP 4314
KAY D++ +GG P+TNCVKML TGTG A++V PEAN DQ+++GGAS CLYCR HI+HP
Sbjct 4353 KAYLDFVNAGGAPLTNCVKMLTPKTGTGIAVSVKPEANADQDTYGGASVCLYCRAHIEHP 4412
Query 4315 NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADAS 4374
+ G C KGK+VQ+P DPVGF L+NT C VC W G+GC+CD LR + + S
Sbjct 4413 DVTGVCKFKGKFVQVPL-HIRDPVGFCLQNTPCNVCQFWIGHGCNCDALRGTTIPQSKDS 4471
Query 4375 TFLNRVCGV-SAARLTPCGTGTSTDVVYRAFDIYN--EKVAGFAKFLKTNCCRFQEKDEE 4431
FLNRV G AR+ PC +G +TDVV+RAFDI N KVAG K+ KTN CRF E D+E
Sbjct 4472 NFLNRVRGSIVNARIEPCASGLTTDVVFRAFDICNYKAKVAGIGKYYKTNTCRFVEVDDE 4531
Query 4432 GNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKY 4491
G+ LDS+FVVKRHTM NY+ E+ Y+LVKDC AVAVHDFF F VD PHI RQRLT+Y
Sbjct 4532 GHRLDSFFVVKRHTMENYELEKRCYDLVKDCDAVAVHDFFIFDVDKVKTPHIVRQRLTEY 4591
Query 4492 TMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERV 4551
TM DLVYALRHFD+ NC+ LK ILV Y CCD YF+ K W+DFVENP+++ VY LGER+
Sbjct 4592 TMMDLVYALRHFDQNNCEVLKSILVKYGCCDASYFDNKLWFDFVENPNVISVYHKLGERI 4651
Query 4552 RQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLM 4611
RQ++L TV+FCD M +G+VGVLTLDNQDLNG WYDFGDFV PG GV IVDSYYS LM
Sbjct 4652 RQAVLNTVKFCDQMVKSGLVGVLTLDNQDLNGKWYDFGDFVITQPGAGVAIVDSYYSYLM 4711
Query 4612 PILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCL 4671
P+L++T LAAE+H D DL KPLI+W LL+YD+T+ ++ LF++YFK WDQ YHPNC+NC
Sbjct 4712 PVLSMTNCLAAETHRDCDLTKPLIEWPLLEYDYTDYKIGLFEKYFKXWDQQYHPNCVNCT 4771
Query 4672 DDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLH 4731
DDRC+LHCANFNVLFS P TSFGP+VRKIFVDGVPFV+S GYH++ELG+V N DV+LH
Sbjct 4772 DDRCVLHCANFNVLFSMTLPGTSFGPIVRKIFVDGVPFVISCGYHYKELGLVMNMDVSLH 4831
Query 4732 SSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDF 4791
RLS KEL++YAADPAMH AS + L D RT CFSVAALT + FQTV+PGNFNKDFYDF
Sbjct 4832 RHRLSLKELMMYAADPAMHIASASALWDLRTPCFSVAALTTGLTFQTVRPGNFNKDFYDF 4891
Query 4792 AVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDC 4851
VSKGFFKEGSSV L+HFFFAQDG+AAI+DY YY YNLPTMCDI+Q+LF +EVVD+YF+
Sbjct 4892 VVSKGFFKEGSSVTLRHFFFAQDGHAAITDYSYYAYNLPTMCDIKQMLFCMEVVDRYFEI 4951
Query 4852 YDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQM 4911
YDGGC+NA++VIVNNLDKSAG PFNK+GKAR+YY+S+SY++QD LFA TKRNV+PTITQM
Sbjct 4952 YDGGCLNASEVIVNNLDKSAGHPFNKFGKARVYYESLSYQEQDELFAMTKRNVLPTITQM 5011
Query 4912 NLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNML 4971
NLKYAISAKNRARTVAGVSI STMTNRQ+HQK+LKS+AATRG+T VIGT+KFYGGW ML
Sbjct 5012 NLKYAISAKNRARTVAGVSILSTMTNRQYHQKMLKSMAATRGSTCVIGTTKFYGGWDFML 5071
Query 4972 KTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQV 5031
KT+Y DV+ PHLMGWDYPKCDRAMPNM RI ASL+LARKH+TCC + RFYRLANECAQV
Sbjct 5072 KTLYKDVDNPHLMGWDYPKCDRAMPNMCRIFASLILARKHSTCCTNTDRFYRLANECAQV 5131
Query 5032 LSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRN 5091
LSE V+CGG YVKPGGTSSGDATTAYANSVFNI QA TANV+AL+ +GN I D+ V++
Sbjct 5132 LSEYVLCGGGYYVKPGGTSSGDATTAYANSVFNILQATTANVSALMGANGNTIVDEEVKD 5191
Query 5092 LQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNF 5151
+Q LY +YR D +FVD +YA+L KHFSMMILSDD VVCYNS+YA +G +ASI+NF
Sbjct 5192 MQFELYVNVYRKSQPDPKFVDRYYAFLNKHFSMMILSDDGVVCYNSDYATKGYIASIQNF 5251
Query 5152 KAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGC 5211
K LYYQNNVFMSEAKCW ETDL KGPHEFCSQHT+ +K GDD +LPYPDPSRIL AGC
Sbjct 5252 KETLYYQNNVFMSEAKCWVETDLKKGPHEFCSQHTLFIKDGDDGYFLPYPDPSRILSAGC 5311
Query 5212 FVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDM 5271
FVDDIVKTDGTLM+ERFVSLAIDAYPLTKH + EY +VF +YLQYI KL+ +LTGHMLD
Sbjct 5312 FVDDIVKTDGTLMVERFVSLAIDAYPLTKHDDPEYQNVFWVYLQYIEKLYKDLTGHMLDS 5371
Query 5272 YSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCC 5331
YSVML DN++++WE FY +YT T LQAVG+CV+C+SQTSLRCG CIRRPFLCCKCC
Sbjct 5372 YSVMLCGDNSAKFWEESFYRDLYTAPTTLQAVGSCVVCHSQTSLRCGTCIRRPFLCCKCC 5431
Query 5332 YDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVF 5391
YDHVI+T HK+VLSV+PYVCNAPGCDV DVT+LYLGGMSY+C H+P SFPLCANG VF
Sbjct 5432 YDHVIATPHKMVLSVSPYVCNAPGCDVADVTKLYLGGMSYFCIDHRPVCSFPLCANGLVF 5491
Query 5392 GLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYG 5451
GLYKN C GS +VT+FN +ATCDWT +GDY LANT TE LKLFAAETL+ATEE K SY
Sbjct 5492 GLYKNMCTGSPSVTEFNRLATCDWTESGDYTLANTTTEPLKLFAAETLRATEEASKQSYA 5551
Query 5452 IATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVV 5511
IAT++E++ +REL L WE GK +PPLNRNYVFTGY +TKNSKVQ+GEY FE+ DY DAV
Sbjct 5552 IATIKEIVGERELLLVWEAGKAKPPLNRNYVFTGYHITKNSKVQLGEYVFERIDYSDAVS 5611
Query 5512 YRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQ 5571
Y+ +TTYKL VGD FVLTSH+V L APT+V QE YV+ITGLYPTL + +EF+++VAN+Q
Sbjct 5612 YKSSTTYKLAVGDIFVLTSHSVATLQAPTIVNQERYVKITGLYPTLTVPEEFANHVANFQ 5671
Query 5572 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5631
K G K+ T+QGPPGTGKSHFAIGLA+YYP+AR+VYTACSHAAVDALCEKA KYL I KC
Sbjct 5672 KAGFSKFVTVQGPPGTGKSHFAIGLAIYYPTARVVYTACSHAAVDALCEKAFKYLNIAKC 5731
Query 5632 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR 5691
SRIIPA+ARVEC+D+FKVN T QY+F T+NALPET+ADI+V DE+SM TNYDLSV+NAR
Sbjct 5732 SRIIPAKARVECYDQFKVNETNSQYLFSTINALPETSADILVVDEVSMCTNYDLSVINAR 5791
Query 5692 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5751
++AKH VY+GDPAQLPAPRTLLT+GTLEPE FNSV RLM +GPD+FL C RCP EIV+
Sbjct 5792 IKAKHIVYVGDPAQLPAPRTLLTRGTLEPENFNSVTRLMCNLGPDIFLSVCYRCPEEIVN 5851
Query 5752 TVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5811
TVSALVY+NKL A K S QCFK+ YKG +THD SSAINRPQ+ V+ F+ NP W KAV
Sbjct 5852 TVSALVYNNKLVAKKPASGQCFKILYKGSVTHDASSAINRPQLNFVKSFIAANPNWSKAV 5911
Query 5812 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKI 5871
FISPYNSQNAVA +LGL TQTVDSSQGSEY YVIF QT +TAH+ N+NRFNVA+TRA+
Sbjct 5912 FISPYNSQNAVARSVLGLTTQTVDSSQGSEYPYVIFCQTADTAHANNINRFNVAVTRAQK 5971
Query 5872 GILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSV 5931
GILC+M+ + L+D L+F + + N LQ++ VTGL+KDCS+ +GLHP APT++SV
Sbjct 5972 GILCVMTSQALFDSLEFAEVSL---NNYKLQSQIVTGLYKDCSRESSGLHPAYAPTYVSV 6028
Query 5932 DIKFKT-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIG 5990
D K+KT + LCV++ +P ++ Y R+IS MGFK++ + YP +FITR+EAIR VR+WIG
Sbjct 6029 DDKYKTSDELCVNL-NVPANVPYSRVISRMGFKLDASIPNYPKLFITRDEAIRQVRSWIG 6087
Query 5991 FDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKH 6050
FDVEG HA+R+A GTN+PLQLGFSTGVN V P G VDTE + T + A+PPPG+QFKH
Sbjct 6088 FDVEGAHASRNACGTNVPLQLGFSTGVNFVVQPVGVVDTEWGSMLTSIAARPPPGEQFKH 6147
Query 6051 LIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCC 6110
L+PLM KG W +VR +IVQMLSDTL LSD FV WAHGFELTS YF KIG E+ CC
Sbjct 6148 LVPLMNKGAAWPIVRRRIVQMLSDTLDKLSDYCTFVCWAHGFELTSASYFCKIGKEQRCC 6207
Query 6111 LCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAH 6170
+C++RA+ +S+ +YACW+HS G+DYVYNPF +DVQQWG+ GNL +NHD++C VH AH
Sbjct 6208 MCNRRASTYSSPLHSYACWSHSSGYDYVYNPFFVDVQQWGYIGNLATNHDRYCSVHQGAH 6267
Query 6171 VASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPV 6230
VAS DA+MTRCLA+H+CF++RV+W + YP I E R+NS CR V+ VV++ALLA +F
Sbjct 6268 VASNDAVMTRCLAIHDCFIERVEWDITYPYISHEKRLNSCCRAVERNVVRAALLAGRFER 6327
Query 6231 LHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCN 6290
++DIGNPK I V V+W +YDAQP S K+++LFY+ + F+DG+CLFWNCN
Sbjct 6328 VYDIGNPKGIPIVDDPVVDWHYYDAQPLS---KKVQQLFYTEDCAKN-FSDGLCLFWNCN 6383
Query 6291 VDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYS 6350
V RYP NAIVCRFDTRV S NLPGCDGGSLYVNKHAFHTPA+D SAF +LK LPFFYYS
Sbjct 6384 VPRYPNNAIVCRFDTRVHSEFNLPGCDGGSLYVNKHAFHTPAYDASAFRDLKPLPFFYYS 6443
Query 6351 DSPCESHG-KQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFS 6409
+PCE HG ++ DIDYVPLKSA CIT CNLGGAVCR HA EYR Y++AYN++ ++GF
Sbjct 6444 TTPCEVHGNGNMLEDIDYVPLKSAVCITACNLGGAVCRKHAAEYRDYMEAYNLVSASGFR 6503
Query 6410 LWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDV 6469
LW YK FD YNLW+TFT++Q LEN+AYNV+ +GHF G GE PV+++N+ +YTK D DV
Sbjct 6504 LWCYKTFDVYNLWSTFTKIQGLENIAYNVIKQGHFTGVEGELPVAVVNDKIYTKSDVNDV 6563
Query 6470 EIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIG 6529
IFENKTTLP N+AFEL+AKR ++ P+ +L NL VD+ V+WDY+R +TIG
Sbjct 6564 CIFENKTTLPTNIAFELYAKRAVRSHPDFNLLRNLEVDVCYKFVLWDYERSNIYGSATIG 6623
Query 6530 VCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQA 6589
VC TDI S+L + FD R G ++ F + NG+LI++ VK A
Sbjct 6624 VCKYTDI------DVNSALNICFDIRDNGSLERFMSLPNGILISDRKVKNYPCIVSSNYA 6677
Query 6590 SVNGVTLIGESVKTQ-----------FNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQM 6638
NG + + +Q F +KKV+ Q +TY+T R + DF P S+M
Sbjct 6678 YFNGTLIRDNTGNSQSSDGEVKQPVTFYIYKKVNNEFVQFTDTYYTLGRTVSDFTPVSEM 6737
Query 6639 ETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFI 6698
E DFL L D FI++YKLE YAFEH+VYGDFS LGGLHL+IGL K+ Q+ + +E+ +
Sbjct 6738 EKDFLALDSDVFIKKYKLEAYAFEHVVYGDFSRTTLGGLHLLIGLYKKHQEGHIIMEEML 6797
Query 6699 PMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISF 6758
+TV NYF+T++ T S K VCSVIDL LDDFV+IIK+ DLSV+SKVVK+ ID I F
Sbjct 6798 KERATVHNYFVTESNTASFKAVCSVIDLKLDDFVDIIKAMDLSVVSKVVKIPIDLTMIEF 6857
Query 6759 MLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMN 6818
MLWCKDG V+TFYP+LQA W+PG+AMP+L+K+Q LE C L NY ++ +P+G+ MN
Sbjct 6858 MLWCKDGQVQTFYPRLQAINDWKPGLAMPSLFKVQNSNLEPCMLPNYKQSIPMPQGVHMN 6917
Query 6819 VAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDF 6878
+AKY QLCQYLNT T+AVP NMRV+HFGAGSDKGVAPG++VLRQWLPT +L+D+DLN++
Sbjct 6918 IAKYMQLCQYLNTCTIAVPANMRVMHFGAGSDKGVAPGSSVLRQWLPTDAILIDNDLNEY 6977
Query 6879 VSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLAL 6938
VSDAD TL GDC TV + DL+ISDMYDP TK V + N++K FF YLC FIK LAL
Sbjct 6978 VSDADITLFGDCVTVRVGQQVDLLISDMYDPSTKVVGETNEAKALFFVYLCNFIKNNLAL 7037
Query 6939 GGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYT 6998
GGS+A+KITEHSW+A+LY+LMG F+WWT F TN NASSSE FLIG NYLG+ KE IDG
Sbjct 7038 GGSVAIKITEHSWSAELYELMGRFAWWTVFCTNANASSSEGFLIGINYLGELKEVIDGNV 7097
Query 6999 MHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIR 7058
MHANYIFWRNT + LS+YSLFD+S+FPLKL+GT V+ LKE+QIN+++ SLL +G+LIIR
Sbjct 7098 MHANYIFWRNTTLMNLSTYSLFDLSRFPLKLKGTPVLQLKESQINELVISLLSQGKLIIR 7157
Query 7059 ENNRVVVSSDILVN 7072
+N+ + VS+D+LVN
Sbjct 7158 DNDTLSVSTDVLVN 7171
>sp|P0C6W3|R1AB_BCHK4 Replicase polyprotein 1ab OS=Bat coronavirus
HKU4 OX=694007 GN=rep PE=1 SV=1
Length=7119
Score = 8614 bits (22351), Expect = 0.0, Method: Composition-based stats.
Identities = 3261/7247 (45%), Positives = 4428/7247 (61%), Gaps = 335/7247 (5%)
Query 8 VNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEALSEAREHLK-NGTCGLVELE-KGV 60
NEK HV ++P+ D+ L F D E A ++ LK G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTDDMACKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMD--GIQYGRSG---ITLGVLVPHVGETP 115
+ L P V++ H +V +A D G R+ LG+ P+
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDQVGAAMMRTTLNAKPLGMFFPYDSSLE 139
Query 116 IAYRNVLLRKNGNKGAGGHSYGIDLKS---YDLGDELGTDPIEDYEQNWNTKHGSGALRE 172
LLRKNG G D K ++ D+L DP Y QN
Sbjct 140 TGEYTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LTRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAG--KSMCTLSEQLDYIESKRGVYC 230
L ++L GG +D CG +G P+ +A+ G + ++S R +
Sbjct 188 LLKKLIGGDCIP-IDQYMCGKNGKPIADYAKIVAKEGLTTLADIEVDVKSRMDSDRFI-V 245
Query 231 CRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQP-RVE 289
+ + W R + Y QT F I S + D K P+ F + S++ ++ P +
Sbjct 246 LNKKLYRVVWNVTRRNVPYPKQTAFTIVSVVQCDD-KDSVPEHTFTIGSQILMVSPLKAT 304
Query 290 KKKTEGFMGRI-RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTEN 348
K R+ + Y + Q+ ++ S + CN C +W T + ++ CG
Sbjct 305 NNKNFNLKQRLLYTFYGKDAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGANY 364
Query 349 LVIE-GPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGR--TRC 405
+ + G +P NA+ CP + HS A +N + + + GG+ T
Sbjct 365 SANDVDLQSSGLVPRNALFLANCPCANNGAC--SHSAAQVYNILDGKACVEVGGKSFTLT 422
Query 406 FGGCVFAYVGCYNKRAYWVPRASA-------DIGSGHTGITGDNVETLNEDLLEILSRER 458
FGG V+AY+GC + Y+VPRA + I +G TG VET N L + +
Sbjct 423 FGGVVYAYMGCCDGTMYFVPRAKSCVSRIGDAIFTGCTGTWDKVVETAN----LFLEKAQ 478
Query 459 VNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGN--YKVTKGKP 516
++N F L E V IL+ TS F + S++ + + N + VT G
Sbjct 479 RSLNFCQQFALTEVVLAILSGT---TSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDY 535
Query 517 VKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQ 576
++ A NIG +C A + + + + + + LD S
Sbjct 536 IRDAINIGAN-----GVCNATINAPFIAFTGLGESFKKVSAIPWKICSNLKSALDYYSSN 590
Query 577 SLRLV-------DAMVYTSDLLTNS---VIIMAYVTGGLVQQTSQWLSNLLGTTVEKLRP 626
+ V D + LL V +V L ++ L + L
Sbjct 591 IMFRVFPYDIPCDVSNFVELLLDCGKLTVATSYFVLRYLDEKFDTVLGTVSSACQTALSS 650
Query 627 IFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKAL 686
A A F+ D +++ K L+ ++ +++ V+ +D+++KA+
Sbjct 651 FLNACVAASRATAGFINDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDIMSKAM 710
Query 687 EMCIDQVTIAGAKLRSLNL--GEVFIAQSKGLYRQCIRGKE---QLQLLMPLKAPKEVTF 741
++ V+ AG KL ++ E + S + + K Q+ L++P K+
Sbjct 711 KLLHTNVSWAGTKLSAIIYEGREALLFNSGTYFCLSTKAKTLQGQMNLVLPGDYNKKTLG 770
Query 742 L-----EGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDK 796
+ D+ D S V + +G+LE P + IVG V V+ + + +D+
Sbjct 771 ILDPVPNADTIDVNANSTVVDVVHGQLE----PTNEHGPSMIVGNYVLVSDKLFVRTEDE 826
Query 797 EQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDERVDKVLNE 856
E Y + G + + +FRLKGG P K VTFG+ EV Y++V IT+++ +D +L+
Sbjct 827 EFYPLCTNGKVVS-TLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLSS 885
Query 857 -KCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEE 915
K + +TVE V +F V+ + V+ L P+ G D++++ Y+++ G+
Sbjct 886 SKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYVYNQDGDC 945
Query 916 NFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEE 975
+SS M S P ++ EE + E++ + + E DD + + + E V
Sbjct 946 AWSSNMTFSINPVEDVEEVEEFIEDDYLSD----ELPIADDEEA----WARAVEEVMP-- 995
Query 976 EEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVI 1035
D +EIE E +P E + + T V+ + S + +V
Sbjct 996 -------LDDILVAEIELEEDPPLETALESVEAEVVETAEAQEPSVESIDSTPSTSTVVG 1048
Query 1036 VNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHV 1095
N ++ +K VA E+DD ++L + VG
Sbjct 1049 EN--DLSVKPMSRVA-------------ETDDVLELETAV-VG----------------- 1075
Query 1096 VGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAV 1155
GP + + + + G+ + QV
Sbjct 1076 -GP----------VSDVTAIVTNDIVSVEQAQQCGVSSLPIQDEAS---ENQVHQVSDLQ 1121
Query 1156 NDKALYEQVVMDYLD---NLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACI 1212
++ L + ++ + +LKPR + K + + SV D
Sbjct 1122 GNELLCSETKVEIVQPRQDLKPR-RSRKSKVDLSKYKHTVINNSVTLVLGDAIQIASLLP 1180
Query 1213 DEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVIT---- 1268
+ L I G + S ++ E ++ + P VGD +
Sbjct 1181 KCILVNAANRH-----LKHGGGIAGVINKASGGDVQEESDEYISNNGPLHVGDSVLLKGH 1235
Query 1269 --SGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCK 1326
+ I VV P + +L R K +++ AG + K + +
Sbjct 1236 GLADAILHVVGPDARNNEDAALLKRCYKAF--NKHTIVVTPLISAGIFSVDPKVSFEYLL 1293
Query 1327 SAF-----------YVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIM 1375
+ + + A +K + L R + A+ IC + A +
Sbjct 1294 ANVTTTTYVVVNNEDIYNTLATPSKPDGLVYSFEGWRGTVRTAKNYGFTCFICTEYSANV 1353
Query 1376 ATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNL 1435
++ K + VD GV ++ Y++++ + +I N + + MP GYVTHG +L
Sbjct 1354 KFLRTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGCS-GICAMPFGYVTHGLDL 1411
Query 1436 EEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSY-SG 1494
++ +R +K P V ++S + + N + + +T E F+ V+ G Y W SG
Sbjct 1412 AQSGNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGGYHSWHLVSG 1469
Query 1495 QRTELGVEFLKR----GDKIVY-----HTLESPVEFHLDGEVLSLDKLKSLLSLREVK-- 1543
V + K G I Y + +++ V L+ ++ L+ R +
Sbjct 1470 DLIVKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFS----DLEACRAYLTSRAAQQV 1525
Query 1544 TIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDT 1603
I+V T+D N T +++ + T+ +Q G T+ G D++ P V G++ FV +
Sbjct 1526 NIEVLVTIDGVNFRTVILNDTTTFRKQLGATFYKGVDISDAFPTVKMGGESLFVADNLSE 1585
Query 1604 LRSEAF-EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ 1662
EYY T D +FL RY S ++WKF G+ S+K ++ NCY+++ ++ +
Sbjct 1586 SEKVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATIMMIDM 1645
Query 1663 L-EVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE-S 1720
L ++KF PALQ AY R + GD +F ALI+AY + T D + + LL A L S
Sbjct 1646 LHDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKAELTVS 1705
Query 1721 AKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESS 1780
AK V C CG + TG+ A +Y G S + L++ + CVCG + LV+ +
Sbjct 1706 AKMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLVEHSAP 1765
Query 1781 FVMMSAPPAEYKLQQG--TFLCANEYTG-NYQCGHYTHITAKETL-YRIDGAHLTKMSEY 1836
++++S + N + G GHY HI K+ L Y+ D LTK S+
Sbjct 1766 WLLVSGLNEVKVSTSTDPIYRAFNVFQGVETSVGHYVHIRVKDGLFYKYDSGSLTKTSDM 1825
Query 1837 KGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQP-IDLVPTQ 1895
K +T V+Y YT V Y LDGVT E+ P L YY KD YYT +P I P
Sbjct 1826 KCKMTSVWYPTVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKPTIKYSPAT 1885
Query 1896 PLPNASFDNFKLTCSNTKFADD-----LNQMTGF--TKPASRELSVTFFPDLNGDVVAID 1948
LP + + N L + D N + GF TKP S++L+ + P+ +GDV+ +
Sbjct 1886 ILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNEDGDVLLSE 1945
Query 1949 YRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVE 2008
+ +Y+ +KKG L KPI+W N KPN LR L+ P+ N + VL
Sbjct 1946 FSNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDNKYTVLQDN 2005
Query 2009 DTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVK---TTEVVGNVILKPSDEGVKVTQ 2065
+Q E P ++V P +++IE K V GN GV V
Sbjct 2006 TSQ-----LVEHNVPVVDDV---PITTRKLIEVKCKGLNKPFVKGNFSFVNDPNGVTVVD 2057
Query 2066 ELGHEDLMAAYVE-NTSITIKKPNELSLALGLKTIATHGIAAI---NSVPWS-KILAYVK 2120
LG +L A YV+ NT + + N S L T+ + + + SV ++L
Sbjct 2058 TLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVESGDLQIVAAGGSVTRRARVLLGAS 2117
Query 2121 PFLGQAAITTSN----------------CAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTN 2164
A T + ++ +F L F K
Sbjct 2118 SLFASFAKITVTATTAACKTAGRGFCKFVVNYGVLQNMFVFLKMLFFLPFNYLWPKKQPT 2177
Query 2165 SRIRASLPTT---IAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMW------------ 2209
I S T + N VK + K + + +
Sbjct 2178 VDIGVSGLRTAGIVTTNIVKQCGTAAYYMLLGKFKRVDWKATLRLFLLLCTTILLLSSIY 2237
Query 2210 -LLLLSICLGSLICVTAAFGVLL------SNFGAPSYCNGVRELYLNSSNVTTMDFCEG- 2261
L+L + L S + + A G+L S G + C+G+ Y N+S M+FC
Sbjct 2238 HLVLFNQVLSSDVMLEDATGILAIYKEVRSYLGIRTLCDGLVVEYRNTS-FDVMEFCSNR 2296
Query 2262 SFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLS 2321
S C CL G DSL Y AL+ +Q I+SY L++ + A E+ LAY+L+T F +L L
Sbjct 2297 SVLCQWCLIGQDSLTRYSALQMLQTHITSYVLNIDWIWFALEFFLAYVLYTSSFNVLLLV 2356
Query 2322 AIMQVFFGYFAS--HFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMD 2379
Q FF Y ++ ++ + ++++ + +V P+ +VR+Y F A +++ K Y H+++
Sbjct 2357 VTAQYFFAYTSAFVNWRAYNYIVSGLFFLVTHIPLHGLVRVYNFLACLWFLRKFYSHVIN 2416
Query 2380 GCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGS 2439
GC + C++CYKRNR TRVE +TIV G KR+FY+ ANGG +C HNWNC+ CDT G+
Sbjct 2417 GCKDTACLLCYKRNRLTRVEASTIVCGTKRTFYIAANGGTSYCCKHNWNCVECDTAGVGN 2476
Query 2440 TFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFV 2499
TFI EVA DL+ +R I PTDQS Y VDSV VK+ + L++++ G YER+PL +F
Sbjct 2477 TFICTEVANDLTTTLRRLIKPTDQSHYYVDSVVVKDAVVELHYNRDGSSCYERYPLCYFT 2536
Query 2500 NLDNLR----ANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVS 2555
NL+ L+ G N +++D + E+ ++SA VYYSQ++C+P+LL+D LV+
Sbjct 2537 NLEKLKFKEVCKTPTGIPEHNFLIYDTNDRGQENLARSACVYYSQVLCKPMLLVDVNLVT 2596
Query 2556 DVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAAR 2615
VGDS E+++KM D+++++F + FSV +KL+ L+ TA + +G VL TF AAR
Sbjct 2597 TVGDSREIAIKMLDSFINSFISLFSVSRDKLEKLINTARDCVRRGDDFQNVLKTFTDAAR 2656
Query 2616 QGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNAR 2674
V++DV+T V++ L+ +H +D+++T + NN++ Y K +++ DLG ID A
Sbjct 2657 GHAGVESDVETTMVVDALQYAHKNDIQLTTECYNNYVPGYIKPDSINTLDLGCLIDLKAA 2716
Query 2675 HINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTK 2734
+N ++ N + +WN DYM LS+ ++QIR A +K NIPFRLT + R N+++ K
Sbjct 2717 SVNQTSMRNANGACVWNSGDYMKLSDSFKRQIRIACRKCNIPFRLTTSKLRAADNILSVK 2776
Query 2735 ISLKG--GKIVSTCF-------KLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIG 2785
S G S K TL A++ + +P ++++ + + I+
Sbjct 2777 FSATKIVGGAPSWLLRVRDLTVKGYCILTLFVFTVAVLSWFCLPSYSIATVNFNDDRILT 2836
Query 2786 YKAIQDGVTRDIISTDDCFANKHAGFDAWF-SQRGGSYKNDKSCPVVAAIITREIGFIVP 2844
YK I++G+ RDI D CFANK+ F WF GG Y+N CP+ A+I G V
Sbjct 2837 YKVIENGIVRDIAPNDVCFANKYGHFSKWFNENHGGVYRNSMDCPITIAVIAGVAGARVA 2896
Query 2845 GLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMG 2904
+P L + + F+ RVF+ N+C+TP I Y F+ S CVL++ECT+F+DA G
Sbjct 2897 NVPAN-LAWVGKQIVLFVSRVFANT-NVCFTPINEIPYDTFSDSGCVLSSECTLFRDAEG 2954
Query 2905 KPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRH 2963
P+CYD +L G+ SY++++P RY + D I+FP +E ++R+ T +YCR
Sbjct 2955 NLNPFCYDPTVLPGASSYADMKPHVRYDMYDSDMYIKFPEVIVESTLRITKTLATQYCRF 3014
Query 2964 GTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSAS 3023
G+CE S G+C+ST+G W L N++Y G++CG D +++ + L QPV +S S
Sbjct 3015 GSCEESAAGVCISTNGSWALYNQNYSTRPGIYCGDDYFDIVRRLAISLFQPVTYFQLSTS 3074
Query 3024 VVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYS 3083
+ G ++ + +T A YY K +R +Y + L++ LC + A L Y+
Sbjct 3075 LAMGLVLCVFLTAAFYYINKVKRALADYTQCAVVAVVAALLNSLCLCFIVANPLLVAPYT 3134
Query 3084 VFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRK--R 3141
Y Y TFY T + +F+ H+ W+ MF +VP W+ A Y + L+H W + +K
Sbjct 3135 AMYYYATFYLTGEPAFIMHISWYVMFGAVVPIWMLASYTVGVMLRHLFWVLAYFSKKHVD 3194
Query 3142 VMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTT 3201
V +G +F++AA F++ K+ Y+ LR+ + + RYL+L+NKYKY+SGA+DT
Sbjct 3195 VFTDGKLNCSFQDAASNIFVIGKDTYVALRNA--ITQDSFVRYLSLFNKYKYYSGAMDTA 3252
Query 3202 SYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVT 3261
SYREA HL KAL +S +G+D+LYQPP S+TS+VLQSG KM+ PSG VE C+VQVT
Sbjct 3253 SYREACAAHLCKALQTYSETGSDILYQPPNCSVTSSVLQSGLVKMSAPSGAVENCIVQVT 3312
Query 3262 CGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQ---AGNVQLRVI 3318
CG+ TLNGLWLD+TV+CPRH++C A+ + +PNY+ LLI K+NHSF+VQ LRV+
Sbjct 3313 CGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVV 3372
Query 3319 GHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKG 3378
HSM LL+L VD +NP TP Y F ++PG +FSVLACYNG P+GV+ +R N TIKG
Sbjct 3373 AHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKG 3432
Query 3379 SFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDT 3438
SFL GSCGSVG+ + ++F YMH MEL G H G+ +G YG F D+QT Q TD
Sbjct 3433 SFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDK 3492
Query 3439 TITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTG 3498
T+NV+AWLYAAV+NG +WF+ + +N A+ + + L+ +TG
Sbjct 3493 YCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVG--TQSIDMLAHRTG 3550
Query 3499 IAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHH 3558
++V M AA++ L G G+TILG + LEDEFTP DV Q GV Q K+I G H
Sbjct 3551 VSVEQMLAAIQSL-HAGFQGKTILGQSTLEDEFTPDDVNMQVMGVVMQSGVKRISYGFIH 3609
Query 3559 WMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLL 3618
W++ TF+ + + ++Q T+++++ +++E T ++ AC M VKHKH F+ LFLL
Sbjct 3610 WLISTFVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLLGFMACVMFTVKHKHTFMSLFLL 3669
Query 3619 PSLATVAYFNMVYMPASW----VMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTA 3674
P + Y N+VY P + ++ + WL + D +Y S +L ++
Sbjct 3670 PVALCLTYANIVYEPQTLISSTLIAVANWLTPTSVYMRTTHF-DFGLYISLSFVLAIIVR 3728
Query 3675 RTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARA 3734
R + L + + Y G+ I+ + ++TS+Y+ V + LA+
Sbjct 3729 RLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYTITVFATVNLAKF 3787
Query 3735 IVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVST 3794
I + Y P L ++ ++L+Y LGY C YFG+F LLN R+ LGVYDY VST
Sbjct 3788 ISGLVFFYAPHLGFILPEVKLVLLIYLGLGYMCTMYFGVFSLLNLKLRVPLGVYDYSVST 3847
Query 3795 QEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQ 3854
QEFR++ GL P++S +A LN KLLGIGG PCIKVATVQSK++D+KCTSVVLL+VLQ
Sbjct 3848 QEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQSKLTDLKCTSVVLLTVLQ 3907
Query 3855 QLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDN 3914
QL +ES+SK W+ CV+LHN+IL A D TEAFE+ V L + L+S VD++ L ++ +N
Sbjct 3908 QLHLESNSKAWSYCVKLHNEILAAVDPTEAFERFVCLFATLMSFSANVDLDALANDLFEN 3967
Query 3915 RATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAA 3973
+ LQA +EFS L +YA TAQ +Y++A+ +GD S VLK L+K++NVAK+ +++D A
Sbjct 3968 SSVLQATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKA 4027
Query 3974 MQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGC 4033
+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GC
Sbjct 4028 VARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGC 4087
Query 4034 VPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINM 4093
VPL+I+PL + KL VV+PD + + + +YA +LW+I + + D+++V+ +++
Sbjct 4088 VPLSIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVVKPTDVVE 4147
Query 4094 DNSPNLAWPLIVTALRANS-AVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNS 4152
N +L WPL++ R++S AVKLQNNE+ P L+ M AG Q C + +A+AYY
Sbjct 4148 TN-ESLTWPLVIECSRSSSSAVKLQNNEIHPKGLKTMVITAGVDQVNC-NSSAVAYYEPV 4205
Query 4153 KGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLN 4212
+G R V+ LLS++ LKWA+ DG I EL+PPC+F+ PKGP+++YLYF+K LN
Sbjct 4206 QGHRMVMGLLSENAHLKWAKVEGKDGF--INIELQPPCKFLIAGPKGPEIRYLYFVKNLN 4263
Query 4213 NLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCV 4272
NL+RG +LG +AATVRLQAG TE +NSTVL+ AFAVDPAKAY DY+ SGG P++N V
Sbjct 4264 NLHRGQLLGHIAATVRLQAGANTEFASNSTVLTLVAFAVDPAKAYLDYVGSGGTPLSNYV 4323
Query 4273 KMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTT 4332
KML TGTG AI+V PEA DQE++GGAS CLYCR HI+HP+ G C K ++VQIP
Sbjct 4324 KMLAPKTGTGVAISVKPEATADQETYGGASVCLYCRAHIEHPDVSGVCKYKTRFVQIPA- 4382
Query 4333 CANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSA-ARLTPC 4391
DPVGF L+N C VC W GYGC+CD LR + + + FLNRV G S ARL PC
Sbjct 4383 HVRDPVGFLLKNVPCNVCQYWVGYGCNCDALRNNTVPQSKDTNFLNRVRGSSVNARLEPC 4442
Query 4392 GTGTSTDVVYRAFDIYN--EKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNY 4449
+G +TDVVYRAFDI N +VAG K+ KTN CRF + D+EG+ LDSYF+VKRHTMSNY
Sbjct 4443 SSGLTTDVVYRAFDICNFKARVAGIGKYYKTNTCRFVQVDDEGHKLDSYFIVKRHTMSNY 4502
Query 4450 QHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCD 4509
+ E+ Y+L+KDC AVA+HDFF F VD PHI RQ LT+YTM DLVYALRHFD+ NC+
Sbjct 4503 ELEKRCYDLLKDCDAVAIHDFFIFDVDKTKTPHIVRQSLTEYTMMDLVYALRHFDQNNCE 4562
Query 4510 TLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAG 4569
LK ILV Y CC+ YF+ K W+DFVENP ++ VY LGER+RQ++L TV+ CD M +G
Sbjct 4563 VLKSILVKYGCCEQSYFDNKLWFDFVENPSVIGVYHKLGERIRQAMLNTVKMCDHMVKSG 4622
Query 4570 IVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDAD 4629
+VGVLTLDNQDLNG WYDFGDFV PG GV IVDSYYS LMP+L++T LAAE+H D D
Sbjct 4623 LVGVLTLDNQDLNGKWYDFGDFVITQPGAGVAIVDSYYSYLMPVLSMTNCLAAETHKDCD 4682
Query 4630 LAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTV 4689
KPLI+W LL+YD+T+ ++ LF++YFKYWDQTYHPNC+NC DDRCILHCANFNVLFS V
Sbjct 4683 FNKPLIEWPLLEYDYTDYKIGLFNKYFKYWDQTYHPNCVNCSDDRCILHCANFNVLFSMV 4742
Query 4690 FPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAM 4749
P TSFGP+VRKIFVDGVPF+VS GYH++ELG+V N D N+H RL+ KEL++YAADPAM
Sbjct 4743 LPNTSFGPIVRKIFVDGVPFIVSCGYHYKELGLVMNMDFNIHRHRLALKELMMYAADPAM 4802
Query 4750 HAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHF 4809
H AS + L D RT CFSVAALT + FQTV+PGNFNKDFYDF VS+GFFKEGSSV LKHF
Sbjct 4803 HIASASALWDLRTPCFSVAALTTGLTFQTVRPGNFNKDFYDFVVSRGFFKEGSSVTLKHF 4862
Query 4810 FFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDK 4869
FFAQDG+AAI+DY YY YNLPTM DI+Q+LF +EVVDKYFD YDGGC+NA++VIVNNLDK
Sbjct 4863 FFAQDGHAAITDYSYYAYNLPTMVDIKQMLFCMEVVDKYFDIYDGGCLNASEVIVNNLDK 4922
Query 4870 SAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGV 4929
SAG PFNK+GKAR+YY+SMSY++QD LFA TKRNV+PTITQMNLKYAISAKNRARTVAGV
Sbjct 4923 SAGHPFNKFGKARVYYESMSYQEQDELFAVTKRNVLPTITQMNLKYAISAKNRARTVAGV 4982
Query 4930 SICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYP 4989
SI STMTNRQ+HQK+LKS+AATRGAT VIGT+KFYGGW MLKT+Y DVE+PHLMGWDYP
Sbjct 4983 SILSTMTNRQYHQKMLKSMAATRGATCVIGTTKFYGGWDFMLKTLYKDVESPHLMGWDYP 5042
Query 4990 KCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGT 5049
KCDRAMPNM RI+ASL+LARKH+TCC S RFYRLANECAQVLSE V+CGG YVKPGGT
Sbjct 5043 KCDRAMPNMCRILASLILARKHSTCCTNSDRFYRLANECAQVLSEYVLCGGGYYVKPGGT 5102
Query 5050 SSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHE 5109
SSGDATTAYANSVFNI QA TANV+AL+S +GN I D+ ++++Q LY +YR D +
Sbjct 5103 SSGDATTAYANSVFNILQATTANVSALMSANGNTIIDREIKDMQFDLYINVYRKVVPDPK 5162
Query 5110 FVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCW 5169
FVD++YA+L KHFSMMILSDD VVCYNS+YAA+G VASI+NFK LYYQNNVFMSEAKCW
Sbjct 5163 FVDKYYAFLNKHFSMMILSDDGVVCYNSDYAAKGYVASIQNFKETLYYQNNVFMSEAKCW 5222
Query 5170 TETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFV 5229
ET+L KGPHEFCSQHT+ +K GDD +LPYPDPSRIL AGCFVDDIVKTDGT+M+ER+V
Sbjct 5223 VETNLEKGPHEFCSQHTLYIKDGDDGYFLPYPDPSRILSAGCFVDDIVKTDGTVMMERYV 5282
Query 5230 SLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEF 5289
SLAIDAYPLTKH + EY +VF +YLQYI KL+ +LTGHMLD YSVML D+++++WE F
Sbjct 5283 SLAIDAYPLTKHDDTEYQNVFWVYLQYIEKLYKDLTGHMLDSYSVMLCGDDSAKFWEEGF 5342
Query 5290 YEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPY 5349
Y +Y+ T LQAVG+CV+C+SQTSLRCG CIRRPFLCCKCCYDHVI+T HK+VLSV+PY
Sbjct 5343 YRDLYSSPTTLQAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHVIATPHKMVLSVSPY 5402
Query 5350 VCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNA 5409
VCNAPGCDV+DVT+LYLGGMSYYC H+P SFPLCANG VFGLYKN C GS ++ +FN
Sbjct 5403 VCNAPGCDVSDVTKLYLGGMSYYCNDHRPVCSFPLCANGLVFGLYKNMCTGSSSIMEFNR 5462
Query 5410 IATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWE 5469
+ATCDW+++GDY LANT TE LKLFAAETL+ATEE K SY IAT++E++ +REL L WE
Sbjct 5463 LATCDWSDSGDYTLANTTTEPLKLFAAETLRATEEASKQSYAIATIKEIVGERELILVWE 5522
Query 5470 VGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLT 5529
VGK +PPLNRNYVFTGY +TKNSKVQ+GEY FE+ DY DAV Y+ +TTYKL VGD FVLT
Sbjct 5523 VGKSKPPLNRNYVFTGYHLTKNSKVQLGEYVFERIDYSDAVSYKSSTTYKLAVGDIFVLT 5582
Query 5530 SHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGK 5589
SH+V LSAPT+V QE Y++ITG+YPT+ + +EF+++V N+QK G KY T+QGPPGTGK
Sbjct 5583 SHSVATLSAPTIVNQERYLKITGIYPTITVPEEFANHVVNFQKAGFSKYVTVQGPPGTGK 5642
Query 5590 SHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKV 5649
SHFAIGLA+YYP+ARIVYTACSHAAVDALCEKA KYL I KCSRIIPA+ARVEC+D+FKV
Sbjct 5643 SHFAIGLAIYYPTARIVYTACSHAAVDALCEKAFKYLNIAKCSRIIPAKARVECYDRFKV 5702
Query 5650 NSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAP 5709
N T QY+F TVNALPE + DI+V DE+SM TNYDLS++N+R++AKH VY+GDPAQLPAP
Sbjct 5703 NDTNSQYLFSTVNALPEISVDILVVDEVSMCTNYDLSIINSRVKAKHIVYVGDPAQLPAP 5762
Query 5710 RTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKS 5769
RTLL +GTLEPE FNSV RLM +GPD+FL C RCP EIV TVSALVY+NKL A KD S
Sbjct 5763 RTLLIRGTLEPENFNSVTRLMCNLGPDIFLSVCYRCPKEIVSTVSALVYNNKLSAKKDAS 5822
Query 5770 AQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGL 5829
QCFK+ +KG +THD SSAINRPQ+ V+ F+ NP W KAVFISPYNSQNAVA +LGL
Sbjct 5823 GQCFKILFKGSVTHDASSAINRPQLNFVKTFIAANPNWSKAVFISPYNSQNAVARSMLGL 5882
Query 5830 PTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFT 5889
TQTVDSSQGSEY YVIF QT +TAH+ N+NRFNVA+TRA+ GILC+M+ + L+D L+F
Sbjct 5883 TTQTVDSSQGSEYPYVIFCQTADTAHANNLNRFNVAVTRAQKGILCVMTSQVLFDSLEFA 5942
Query 5890 SLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFK-TEGLCVDIPGIP 5948
L + N LQ++ VTGLFKDCS+ TGL P APT+LSVD K+K T+ LCV++ I
Sbjct 5943 ELSL---NNYKLQSQIVTGLFKDCSREDTGLPPAYAPTYLSVDAKYKTTDELCVNL-NIT 5998
Query 5949 KDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLP 6008
++TY R+IS MGFK++ + GYP +FITR+EAIR VR+W+GFDVEG HA+R+A GTN+P
Sbjct 5999 PNVTYSRVISRMGFKLDATIPGYPKLFITRDEAIRQVRSWVGFDVEGAHASRNACGTNVP 6058
Query 6009 LQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKI 6068
LQLGFSTGVN V P G VDTE + T ++A+PPPG+QFKHL+PLM KG W +VR +I
Sbjct 6059 LQLGFSTGVNFVVQPVGVVDTEWGSMLTTISARPPPGEQFKHLVPLMNKGATWPIVRRRI 6118
Query 6069 VQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYAC 6128
VQMLSDTL LSD FV WAHGFELTS YF KIG E+ C +C +RA+ FS+ +YAC
Sbjct 6119 VQMLSDTLDKLSDYCTFVCWAHGFELTSASYFCKIGKEQRCSMCSRRASTFSSPLQSYAC 6178
Query 6129 WNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECF 6188
W+HS G+DYVYNPF +DVQQWG+ GNL +NHD++C +H AHVAS DAIMTRCLA+++CF
Sbjct 6179 WSHSSGYDYVYNPFFVDVQQWGYVGNLATNHDRYCGIHAGAHVASSDAIMTRCLAIYDCF 6238
Query 6189 VKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEV 6248
++RVDW V YP I E ++NS CR V+ VV+SA+L+ KF ++DIGNPK I + + V
Sbjct 6239 IERVDWDVTYPYISHEQKLNSCCRTVERNVVRSAVLSGKFEKIYDIGNPKGIAIISEP-V 6297
Query 6249 EWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVL 6308
EW FYDAQP S+K K LFY+ F DG+CLFWNCNV +YP+NA+VCRFDTRV
Sbjct 6298 EWHFYDAQPLSNKVKK---LFYTDDVSKQ-FEDGLCLFWNCNVSKYPSNAVVCRFDTRVH 6353
Query 6309 SNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHG-KQVVSDIDY 6367
S NLPGC+GGSLYVNKHAFHTPA+D +AF +LK LPFFYYS +PCE HG ++ DIDY
Sbjct 6354 SEFNLPGCNGGSLYVNKHAFHTPAYDINAFRDLKPLPFFYYSTTPCEVHGSGNMLEDIDY 6413
Query 6368 VPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTR 6427
VPLKSA CIT CNLGGAVCR HA EYR Y++AYN++ +AGF LW+YK FD YNLW+TF +
Sbjct 6414 VPLKSAVCITACNLGGAVCRKHAAEYRDYMEAYNIVSAAGFRLWVYKTFDIYNLWSTFVK 6473
Query 6428 LQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELW 6487
+Q LEN+A+NV+ +GHF G GE PV+++N+ ++TK DV IF+N+T LP NVAFEL+
Sbjct 6474 VQGLENIAFNVIKQGHFTGVDGELPVAVVNDKIFTKNGTDDVCIFKNETALPTNVAFELY 6533
Query 6488 AKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSS 6547
AKR ++ P++ +L NL VD+ N V+WDY R +TIGVC TDI +
Sbjct 6534 AKRAVRSHPDLNLLRNLEVDVCYNFVLWDYDRNNIYGTTTIGVCKYTDI------DVNPN 6587
Query 6548 LTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQ--F 6605
L + FD R +G ++ F + NGVLI++ +K GP A NG L K F
Sbjct 6588 LNMCFDIRDKGSLERFMSMPNGVLISDRKIKNYPCISGPKHAYFNGAILRNIDAKQPVIF 6647
Query 6606 NYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIV 6665
+KKV+ +T++T R + DF + ME DFL L D FI++Y LE YAFEH+V
Sbjct 6648 YLYKKVNNEFVSFSDTFYTCGRTVGDFTVLTPMEEDFLVLDSDVFIKKYGLEDYAFEHVV 6707
Query 6666 YGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVID 6725
YGDFSH LGGLHL+IGL K+ ++ + +E+ + +TV NYFITD+ T S K VCSVID
Sbjct 6708 YGDFSHTTLGGLHLLIGLYKKMREGHILMEEMLKDRATVHNYFITDSNTASYKAVCSVID 6767
Query 6726 LLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVA 6785
L LDDFV IIK DL V+SKVVKV ID I FMLWC+DG V+TFYP+LQA+ W+PG+
Sbjct 6768 LRLDDFVTIIKEMDLDVVSKVVKVPIDLTMIEFMLWCRDGKVQTFYPRLQATNDWKPGLT 6827
Query 6786 MPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHF 6845
MP+L+K+Q+M LE C L NY ++ +P G+ MNVAKY QLCQYLNT TLAVP NMRVIHF
Sbjct 6828 MPSLFKVQQMNLEPCLLANYKQSIPMPNGVHMNVAKYMQLCQYLNTCTLAVPANMRVIHF 6887
Query 6846 GAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISD 6905
GAG +KGVAPGT+VLRQWLP +L+D+DLN+FVSDAD T+ GDC TVH + DL+ISD
Sbjct 6888 GAGCEKGVAPGTSVLRQWLPLDAVLIDNDLNEFVSDADITIFGDCVTVHVGQQVDLLISD 6947
Query 6906 MYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWW 6965
MYDP TK V + N +K FF YLC FIK LALGGS+A+KITEHSW+ADLYK+MG F++W
Sbjct 6948 MYDPCTKAVGEVNQTKALFFVYLCNFIKNNLALGGSVAIKITEHSWSADLYKIMGRFAYW 7007
Query 6966 TAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKF 7025
T F TN NASSSE FLIG N+LG+ KE+IDG MHANYIFWRN+ P+ LS+YSLFD+S+F
Sbjct 7008 TVFCTNANASSSEGFLIGINFLGELKEEIDGNVMHANYIFWRNSTPMNLSTYSLFDLSRF 7067
Query 7026 PLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
PLKL+GT V+ LKE+QIN+++ SLL +G+L+IR+N+ + VS+D+LVN
Sbjct 7068 PLKLKGTPVLQLKESQINELVISLLSQGKLLIRDNDTLNVSTDVLVN 7114
>sp|P0C6W1|R1AB_BC133 Replicase polyprotein 1ab OS=Bat coronavirus
133/2005 OX=389230 GN=rep PE=3 SV=1
Length=7126
Score = 8605 bits (22329), Expect = 0.0, Method: Composition-based stats.
Identities = 3248/7244 (45%), Positives = 4415/7244 (61%), Gaps = 322/7244 (4%)
Query 8 VNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEALSEAREHLK-NGTCGLVELE-KGV 60
NEK HV ++P+ D+ L F D E A ++ LK G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTEDMASKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMD--GIQYGRSG---ITLGVLVPHVGETP 115
+ L P V++ H +V +A D G R+ LG+ P+
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDHVGAAMMRTTLNVKPLGMFFPYDSSLE 139
Query 116 IAYRNVLLRKNGNKGAGGHSYGIDLKS---YDLGDELGTDPIEDYEQNWNTKHGSGALRE 172
LLRKNG G D K ++ D+L DP Y QN
Sbjct 140 TGEHTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LTRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAG--KSMCTLSEQLDYIESKRGVYC 230
L ++L GG VD CG +G P+ +A+ G + ++S R +
Sbjct 188 LLKKLIGGDCIP-VDQYMCGKNGKPIADYAKIVAKEGLTTLADIEVDVKSRMDSDRFI-V 245
Query 231 CRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQP-RVE 289
+ + W R + Y QT F + S + D K P+ F + S++ ++ P +
Sbjct 246 LNKKLYRVVWNVTRRNVPYSKQTAFTVVSVIQCDD-KESVPEHTFTIGSQILMVSPLKAT 304
Query 290 KKKTEGFMGRI-RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTEN 348
K R+ + Y + Q+ ++ S + CN C +W T + ++ CG
Sbjct 305 NNKNFNLKQRLLHTFYGKEAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGANY 364
Query 349 LVIE-GPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGR--TRC 405
+ + G +P NA+ CP + H+ A ++ + + + GG+ T
Sbjct 365 SANDVDLQSSGLVPKNALFLANCPCANNGAC--SHNAAQVYSILDGKACVEVGGKSFTLT 422
Query 406 FGGCVFAYVGCYNKRAYWVPRASA-------DIGSGHTGITGDNVETLNEDLLEILSRER 458
FGG V+AY+GC + Y+VPRA + I +G TG VET N L + +
Sbjct 423 FGGVVYAYMGCCDGTMYFVPRAKSCVSRIGDAIFTGCTGTWDKVVETAN----LFLEKAQ 478
Query 459 VNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGN--YKVTKGKP 516
++N F L E V IL+ TS F + S++ + + N + VT G
Sbjct 479 HSLNFCQQFALTEVVLAILSGT---TSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDY 535
Query 517 VKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQ 576
++ A NIG +C A + + + + + LD
Sbjct 536 IRDAINIGAN-----GVCNATINAPFIAFTGLGESFKKVAAIPWKICSNLKSALDYYCSN 590
Query 577 SLRLV-------DAMVYTSDLLTNS---VIIMAYVTGGLVQQTSQWLSNLLGTTVEKLRP 626
+ V D + LL V +V L ++ L + L
Sbjct 591 IMFRVFPYDIPCDVNDFVELLLDCGKLTVATSYFVLRYLDEKFDTVLGTVSNACQTALSS 650
Query 627 IFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKAL 686
A A F+ D +++ K L+ ++ +++ V+ +D+++KA+
Sbjct 651 FLNACVAASRATAGFISDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDIMSKAM 710
Query 687 EMCIDQVTIAGAKLRSLNL--GEVFIAQSKGLYRQCIRGK---EQLQLLMPLKAPKEVTF 741
++ V+ AG KL ++ E + S + + K +Q+ L++P K+
Sbjct 711 KLLHTNVSWAGTKLSAIIYEGREALLFNSGTYFCLSTKAKTLQDQMNLVLPGDYNKKTLG 770
Query 742 L-----EGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDK 796
+ D+ D S V + +G+LE P + IVG V V+ + + D+
Sbjct 771 ILDPVPNADTIDVTANSTVVDVVHGQLE----PTNEHGPSMIVGNYVLVSDKLFVRTDDE 826
Query 797 EQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDERVDKVLNE 856
E Y G + + +FRLKGG P K VTFG+ EV Y++V IT+++ +D +L+
Sbjct 827 EFYPLCINGKVVS-TLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLSS 885
Query 857 -KCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEE 915
K + +TVE V +F V+ + V+ L P+ G D++++ Y+++ G+
Sbjct 886 SKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYVYNQDGDC 945
Query 916 NFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEE 975
+SS M S P ++ EE + E++ + + E DD + + + E V +
Sbjct 946 AWSSNMTFSINPVEDVEEVEEFIEDDYLSD----ELPIADDEEA----WTRAVEEVMPLD 997
Query 976 EEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVI 1035
+ ++ E +E E E + L + + + + + + +
Sbjct 998 DILVAEIELE-EDLPLETALESVEAEVGESISDELCVVETAKAQEPSVESTDSTPSTSTV 1056
Query 1036 VNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHV 1095
V+ ++ +K VA G + + V
Sbjct 1057 VSENDLSVKPMSRVA-------------------------ETGDVLEVETAVVGGPVSDV 1091
Query 1096 VGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAV 1155
+ DI ++ A + G+ + V +
Sbjct 1092 TASVVT--NDIVSVEQAQQ--------------CGVSSLPIQD--EASENQVHQVPDLQC 1133
Query 1156 NDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEV 1215
+ E ++ +L+PR K + + SV D V
Sbjct 1134 TSETKVE--IVQPRQDLRPR-RLRKSKVDLSKYKHTVINNSVTLVLGDAIQIASLLPKCV 1190
Query 1216 TTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVIT------S 1269
L I G + S ++ E ++ P VGD + +
Sbjct 1191 LVNAANRH-----LKHGGGIAGAINKASGGDVQEESDEYISNSGPLHVGDSVLLKGYGLA 1245
Query 1270 GDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAF 1329
I VV P + +L R K +++ +G + K + + +
Sbjct 1246 DAILRVVGPDARNNEDAALLKRCYKTF--NKHTIVVTPLISSGIFSVDPKVSFEYLLANV 1303
Query 1330 -----------YVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATI 1378
+ + A +K + L R + A+ IC + A + +
Sbjct 1304 TTTTYVVVNNEDIYNTLATPSKPDGLVYSFEGWRGTVRTAKNYGFTCFICTEYSANVKFL 1363
Query 1379 QRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEA 1438
+ K + VD GV ++ Y++++ + +I N + MP GYVTHG +L ++
Sbjct 1364 RTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGCP-GICAMPFGYVTHGLDLAQS 1421
Query 1439 ARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSY-SGQRT 1497
+R +K P V ++S + + N + + +T E F+ V+ G Y W SG
Sbjct 1422 GNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGGYHSWHLVSGDLI 1479
Query 1498 ELGVEFLKR----GDKIVY-----HTLESPVEFHLDGEVLSLDKLKSLLSLREVK--TIK 1546
V + K G I Y + +++ V L+ ++ L+ R + I+
Sbjct 1480 VKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFS----DLEACRAYLTSRAAQQVNIE 1535
Query 1547 VFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDD-TLR 1605
V T+D N T +++ + T+ +Q G T+ G D++ P V G++ FV + +
Sbjct 1536 VLVTIDGVNFRTVILNDATTFRKQLGATFYKGVDISDALPTVKMGGESLFVADNLSESEE 1595
Query 1606 SEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQL-E 1664
EYY T D +FL RY S ++WKF G+ S+K ++ NCY+++ ++ + L +
Sbjct 1596 VVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATIMMIDMLHD 1655
Query 1665 VKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE-SAKR 1723
+KF PALQ AY R + GD +F ALI+AY + T D + + LL A L SAK
Sbjct 1656 IKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKAELTVSAKM 1715
Query 1724 VLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVM 1783
V C CG + TG+ A +Y G S + L++ + CVCG + LV+ + +++
Sbjct 1716 VWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLVEHSTPWLL 1775
Query 1784 MSAPPAEYKLQQG--TFLCANEYTG-NYQCGHYTHITAKETL-YRIDGAHLTKMSEYKGP 1839
+S + N + G GHY H+ K+ L Y+ D LTK S+ K
Sbjct 1776 VSGLNEVKVSTSTDPVYRAFNVFQGVETSVGHYVHVRVKDGLFYKYDSGSLTKTSDMKCK 1835
Query 1840 VTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQP-IDLVPTQPLP 1898
+T V+Y + YT V Y LDGVT E+ P L YY KD YYT +P I P LP
Sbjct 1836 MTSVWYPKVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKPTIKYSPATILP 1895
Query 1899 NASFDNFKLTCSNTKFADD-----LNQMTGF--TKPASRELSVTFFPDLNGDVVAIDYRH 1951
+ + N L + D N + GF TKP S++L+ + P+ +GDV+ ++ +
Sbjct 1896 GSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNEDGDVLLSEFNN 1955
Query 1952 YSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQ 2011
Y+ +KKG L KPI+W N KPN LR L+ P+ N + VL +Q
Sbjct 1956 YNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDNKYTVLQDNTSQ 2015
Query 2012 GMDNLACESQQPTSEEVVENPTIQKEVIECDVK---TTEVVGNVILKPSDEGVKVTQELG 2068
+ E P E+V +++IE K V GN GV V LG
Sbjct 2016 LI-----EPNVPVVEDVS---ITTRKLIEVKCKGLNKPFVKGNFSFVNDPNGVTVVDTLG 2067
Query 2069 HEDLMAAYVE-NTSITIKKPNELSLALGLKTIATHGIAAI---NSVPWS-KILAYVKPFL 2123
+L A YV+ NT + + N S L T+ + + + SV ++L
Sbjct 2068 LTELRALYVDINTRYIVLRDNNWSSLFKLHTVESGDLQIVANGGSVTRRARVLLGASSLF 2127
Query 2124 GQAAITTSNCAKRLAQRVFNNYMPYVFTL----------------LFQLCTFTKSTNSRI 2167
A T + ++ +V F K +
Sbjct 2128 ASFAKITVTATTAACKTAGRSFCKFVVNYGVLQNMFLFLKMLFFLPFNYLWPKKQPTVDV 2187
Query 2168 RASLPTT---IAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVT 2224
S T + N VK + K + + + L + L S+ +
Sbjct 2188 GVSGLRTAGVVTTNIVKQCGTAAYYMLLGKFKRVDWKATLRLFLLLCTTILLLSSIYHLV 2247
Query 2225 AAFGVLLSN-------------------FGAPSYCNGVRELYLNSSNVTTMDFCEG-SFP 2264
VL S+ G + C+G+ Y N+S +DFC S
Sbjct 2248 IFNQVLSSDVMLEDATGILAMYKEVRSYLGIRTLCDGLAVEYRNTS-FDVVDFCSNRSVL 2306
Query 2265 CSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIM 2324
C CL G DSL Y AL+ +Q I+SY L++ + A E+ LAY+L+T F +L L
Sbjct 2307 CQWCLIGQDSLTRYSALQMLQTHITSYVLNIDWIWFALEFFLAYVLYTSSFNVLLLVVTA 2366
Query 2325 QVFFGYFAS--HFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCT 2382
Q FF Y ++ ++ + ++++ + +V P+ +VR+Y F A +++ K Y H+++GC
Sbjct 2367 QYFFAYTSAFVNWRAYNYIVSGLFFLVTHIPLHGLVRVYNFLACLWFLRKFYSHVINGCK 2426
Query 2383 SSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFI 2442
+ C++CYKRNR TRVE +TIV G KR+FY+ ANGG +C HNWNC+ CDT G+TFI
Sbjct 2427 DTACLLCYKRNRLTRVEASTIVCGTKRTFYIAANGGTSYCCKHNWNCVECDTAGVGNTFI 2486
Query 2443 SDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLD 2502
EVA DL+ +R I PTDQS Y VDSV VK+ + L++++ G YER+PL +F NL+
Sbjct 2487 CTEVANDLTTTLRRLIKPTDQSHYYVDSVVVKDAVVELHYNRDGSSCYERYPLCYFTNLE 2546
Query 2503 NLR----ANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVG 2558
L+ G N +++D + E+ ++SA VYYSQ++C+P+LL+D LV+ VG
Sbjct 2547 KLKFKEVCKTPTGIPEHNFLIYDTNDRGQENLARSACVYYSQVLCKPMLLVDVNLVTTVG 2606
Query 2559 DSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGV 2618
DS E+++KM D+++++F + FSV +KL+ L+ TA + +G VL TF AAR
Sbjct 2607 DSREIAIKMLDSFINSFISLFSVSRDKLEKLINTARDCVRRGDDFQTVLKTFTDAARGHA 2666
Query 2619 -VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHIN 2677
V++DV+T V++ L+ +H +D+++T + NN++ Y K +++ DLG ID A +N
Sbjct 2667 GVESDVETTMVVDALQYAHKNDIQLTTECYNNYVPGYIKPDSINTLDLGCLIDLKAASVN 2726
Query 2678 AQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISL 2737
++ N + +WN DYM LS+ ++QIR A +K NIPFRLT + R N+++ K S
Sbjct 2727 QTSMRNANGACVWNSGDYMKLSDSFKRQIRIACRKCNIPFRLTTSKLRAADNILSVKFSA 2786
Query 2738 KG--GKIVSTCF-------KLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKA 2788
G S K TL A++ + +P ++++ + + I+ YK
Sbjct 2787 TKIVGGAPSWLLRVRDLTVKGYCILTLFVFTVAVLSWFCLPSYSIATVNFNDDRILTYKV 2846
Query 2789 IQDGVTRDIISTDDCFANKHAGFDAWF-SQRGGSYKNDKSCPVVAAIITREIGFIVPGLP 2847
I++G+ RDI D CFANK+ F WF GG Y+N CP+ A+I G V +P
Sbjct 2847 IENGIVRDIAPNDACFANKYGHFSKWFNENHGGVYRNSVDCPITIAVIAGVAGARVANVP 2906
Query 2848 GTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPV 2907
T L + + F+ RVF+ N+C+TP+ I Y F+ S CVL++ECT+F+DA G
Sbjct 2907 AT-LAWVGRQIVLFVSRVFANT-NVCFTPTNEIPYDTFSDSGCVLSSECTLFRDAEGNLN 2964
Query 2908 PYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRHGTC 2966
P+CYD +L G+ SY++++P RY + D I+FP E ++R+ T +YCR G+C
Sbjct 2965 PFCYDPTVLPGASSYADMKPHVRYDMYDSDMYIKFPEVIFESTLRITKTLATQYCRFGSC 3024
Query 2967 ERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVA 3026
E S G+C+ST+G W L N++Y G++CG D +++ + L QPV +S S+
Sbjct 3025 EESAAGVCISTNGSWALYNQNYSTRPGIYCGDDYFDIVRRLAVSLFQPVTYFQLSTSLAM 3084
Query 3027 GGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFY 3086
G ++ + +T A YY K +R +Y + L++ LC + A L Y+ Y
Sbjct 3085 GLVLCVFLTAAFYYINKVKRALADYTQCAVVAVVAALLNSLCLCFIVANPLLVAPYTAMY 3144
Query 3087 LYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRK--RVMF 3144
Y TFY T + +F+ H+ W+ MF +VP W+ A Y + L+H W + +K V
Sbjct 3145 YYATFYLTGEPAFIMHISWYVMFGTVVPIWMLASYTVGVMLRHLFWVLAYFSKKHVDVFT 3204
Query 3145 NGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYR 3204
+G +F++AA F++ K+ Y+ LR+ + + RYL+L+NKYKY+SGA+DT SYR
Sbjct 3205 DGKLNCSFQDAASNIFVIGKDTYVALRNA--ITQDSFVRYLSLFNKYKYYSGAMDTASYR 3262
Query 3205 EAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGT 3264
EA HL KAL +S +G+D+LYQPP S+TS+VLQSG KM+ PSG VE C+VQVTCG+
Sbjct 3263 EACAAHLCKALQTYSETGSDILYQPPNCSVTSSVLQSGLVKMSAPSGAVENCIVQVTCGS 3322
Query 3265 TTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQ---AGNVQLRVIGHS 3321
TLNGLWLD+TV+CPRH++C A+ + +PNY+ LLI K+NHSF+VQ LRV+ HS
Sbjct 3323 MTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVVAHS 3382
Query 3322 MQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFL 3381
M LL+L VD +NP TP Y F ++PG +FSVLACYNG P+GV+ +R N TIKGSFL
Sbjct 3383 MVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGSFL 3442
Query 3382 NGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTIT 3441
GSCGSVG+ + ++F YMH MEL G H G+ +G YG F D+QT Q TD T
Sbjct 3443 CGSCGSVGYTENGGVLNFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDKYCT 3502
Query 3442 LNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAV 3501
+NV+AWLYAAV+NG +WF+ + +N A+ + + L+ +TG++V
Sbjct 3503 INVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVG--TQSIDMLAHRTGVSV 3560
Query 3502 LDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWML 3561
M AA++ L G G+TILG + LEDEFTP DV Q GV Q K+I G HW++
Sbjct 3561 EQMLAAIQSL-HAGFQGKTILGQSTLEDEFTPDDVNMQVMGVVMQSGVKRISYGFMHWLM 3619
Query 3562 LTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSL 3621
T + + + ++Q T+++++ +++E T + AC M VKHKH FL LFLLP
Sbjct 3620 STLVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLFGFMACVMFTVKHKHTFLSLFLLPVA 3679
Query 3622 ATVAYFNMVYMPASWV----MRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTV 3677
+ Y N+VY P + V + + WL + L D +Y S +L ++ R
Sbjct 3680 LCLTYANIVYEPQTLVSSTLIAVANWLTPTSVYMRTTHL-DFGLYISLSFVLAIIVRRLY 3738
Query 3678 YDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVF 3737
+ L + + Y G+ I+ + ++TS+Y+ V + LA+ I
Sbjct 3739 RPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYTITVFATVNLAKFISG 3797
Query 3738 VCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEF 3797
+ Y P L ++ ++L+Y LGY C YFG+F LLN R+ LGVYDY VSTQEF
Sbjct 3798 LVFLYAPHLGFILPEVKLVLLIYLCLGYMCTMYFGVFSLLNLKLRVPLGVYDYSVSTQEF 3857
Query 3798 RYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLR 3857
R++ GL P++S +A LN KLLGIGG PCIKVATVQSK++D+KCTSVVLL+VLQQL
Sbjct 3858 RFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQSKLTDLKCTSVVLLTVLQQLH 3917
Query 3858 VESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRAT 3917
+ES+SK W+ CV+LHN+IL A D TEAFE+ V L + L+S VD++ L ++ +N +
Sbjct 3918 LESNSKAWSYCVKLHNEILAAVDPTEAFERFVCLFATLMSFSANVDLDALANDLFENSSV 3977
Query 3918 LQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQR 3976
LQA +EFS L +YA TAQ +Y++A+ +GD S VLK L+K++NVAK+ +++D A+ R
Sbjct 3978 LQATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVAR 4037
Query 3977 KLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPL 4036
KLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL
Sbjct 4038 KLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPL 4097
Query 4037 NIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNS 4096
+I+PL + KL VV+PD + + + +YA +LW++ + + D+++V+ +++ N
Sbjct 4098 SIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDVTVINNVDNEVVKPTDVVETN- 4156
Query 4097 PNLAWPLIVTALRANS-AVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGG 4155
+L WPL++ RA+S AVKLQNNE+ P L+ M AG Q C+ +A+AYY +G
Sbjct 4157 ESLTWPLVIECSRASSSAVKLQNNEIHPKGLKTMVVTAGIDQVNCS-SSAVAYYEPVQGH 4215
Query 4156 RFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLN 4215
R V+ LLS++ LKWA+ DG I EL+PPC+F+ PKGP+++YLYF+K LNNL+
Sbjct 4216 RMVMGLLSENAHLKWAKVEGKDGF--INIELQPPCKFLIAGPKGPEIRYLYFVKNLNNLH 4273
Query 4216 RGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKML 4275
RG +LG +AATVRLQAG TE +NSTVL+ AFAVDPAKAY DY+ SGG P++N VKML
Sbjct 4274 RGQLLGHIAATVRLQAGANTEFASNSTVLTLVAFAVDPAKAYLDYVGSGGTPLSNYVKML 4333
Query 4276 CTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCAN 4335
TGTG AI+V PEA DQE++GGAS CLYCR HI+HP+ G C K ++VQIP
Sbjct 4334 APKTGTGVAISVKPEATADQETYGGASVCLYCRAHIEHPDVSGVCKYKTRFVQIPA-HVR 4392
Query 4336 DPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSA-ARLTPCGTG 4394
DPVGF L+N C VC W GYGC+CD LR + + + FLNRV G S ARL PC +G
Sbjct 4393 DPVGFLLKNVPCNVCQYWVGYGCNCDALRNNTVPQSKDTNFLNRVRGSSVNARLEPCSSG 4452
Query 4395 TSTDVVYRAFDIYN--EKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHE 4452
+TDVVYRAFDI N +VAG K+ KTN CRF + D+EG+ LDSYF+VKRHTMSNY+ E
Sbjct 4453 LTTDVVYRAFDICNFKARVAGIGKYYKTNTCRFVQVDDEGHKLDSYFIVKRHTMSNYELE 4512
Query 4453 ETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLK 4512
+ Y+L+KDC AVA+HDFF F VD PHI RQ LT+YTM DLVYALRHFD+ NC+ LK
Sbjct 4513 KRCYDLLKDCDAVAIHDFFIFDVDKTKTPHIVRQSLTEYTMMDLVYALRHFDQNNCEVLK 4572
Query 4513 EILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVG 4572
ILV Y CC+ YF+ K W+DFVENP ++ VY LGER+RQ++L TV+ CD M +G+VG
Sbjct 4573 SILVKYGCCEQSYFDNKLWFDFVENPSVIGVYHKLGERIRQAMLNTVKMCDHMVKSGLVG 4632
Query 4573 VLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAK 4632
VLTLDNQDLNG WYDFGDFV PG GV IVDSYYS LMP+L++T LAAE+H D D K
Sbjct 4633 VLTLDNQDLNGKWYDFGDFVITQPGAGVAIVDSYYSYLMPVLSMTNCLAAETHKDCDFNK 4692
Query 4633 PLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPP 4692
PLI+W LL+YD+T+ ++ LF++YFK+WDQTYHPNC+NC DDRCILHCANFNVLFS V P
Sbjct 4693 PLIEWLLLEYDYTDYKIGLFNKYFKHWDQTYHPNCVNCGDDRCILHCANFNVLFSMVLPN 4752
Query 4693 TSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAA 4752
TSFGP+VRKIFVDGVPF+VS GYH++ELG+V N DVN+H RL+ KEL++YAADPAMH A
Sbjct 4753 TSFGPIVRKIFVDGVPFIVSCGYHYKELGLVMNMDVNIHRHRLALKELMMYAADPAMHIA 4812
Query 4753 SGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFA 4812
S + L D RT CFSVAALT + FQTV+PGNFNKDFYDF VS+GFFKEGSSV LKHFFFA
Sbjct 4813 SASALWDLRTPCFSVAALTTGLTFQTVRPGNFNKDFYDFVVSRGFFKEGSSVTLKHFFFA 4872
Query 4813 QDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAG 4872
QDG+AAI+DY YY YNLPTM DI+Q+LF +EVVDKYFD YDGGC+NA++VIVNNLDKSAG
Sbjct 4873 QDGHAAITDYSYYAYNLPTMVDIKQMLFCMEVVDKYFDIYDGGCLNASEVIVNNLDKSAG 4932
Query 4873 FPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSIC 4932
PFNK+GKAR+YY+SMSY++QD LFA TKRNV+PTITQMNLKYAISAKNRARTVAGVSI
Sbjct 4933 HPFNKFGKARVYYESMSYQEQDELFAVTKRNVLPTITQMNLKYAISAKNRARTVAGVSIL 4992
Query 4933 STMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCD 4992
STMTNRQ+HQK+LKS+AATRGAT VIGT+KFYGGW MLKT+Y DVE+PHLMGWDYPKCD
Sbjct 4993 STMTNRQYHQKMLKSMAATRGATCVIGTTKFYGGWDFMLKTLYKDVESPHLMGWDYPKCD 5052
Query 4993 RAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSG 5052
RAMPNM RI+ASL+LARKH+TCC S RFYRLANECAQVLSE V+CGG YVKPGGTSSG
Sbjct 5053 RAMPNMCRILASLILARKHSTCCTNSDRFYRLANECAQVLSEYVLCGGGYYVKPGGTSSG 5112
Query 5053 DATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVD 5112
DATTAYANSVFNI QA TANV+AL+S +GN I D+ ++++Q LY +YR D +FVD
Sbjct 5113 DATTAYANSVFNILQATTANVSALMSANGNTIIDREIKDMQFDLYINVYRKVVPDPKFVD 5172
Query 5113 EFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTET 5172
++YA+L KHFSMMILSDD VVCYNS+YAA+G VASI+NFK LYYQNNVFMSEAKCW ET
Sbjct 5173 KYYAFLNKHFSMMILSDDGVVCYNSDYAAKGYVASIQNFKETLYYQNNVFMSEAKCWVET 5232
Query 5173 DLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLA 5232
+L KGPHEFCSQHT+ +K GDD +LPYPDPSRIL AGCFVDDIVKTDGT+M+ER+VSLA
Sbjct 5233 NLEKGPHEFCSQHTLYIKDGDDGYFLPYPDPSRILSAGCFVDDIVKTDGTVMMERYVSLA 5292
Query 5233 IDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEA 5292
IDAYPLTKH + EY +VF +YLQYI KL+ +LTGHMLD YSVML D+++++WE FY
Sbjct 5293 IDAYPLTKHDDTEYQNVFWVYLQYIEKLYKDLTGHMLDSYSVMLCGDDSAKFWEEGFYRD 5352
Query 5293 MYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCN 5352
+Y+ T LQAVG+CV+C+SQTSLRCG CIRRPFLCCKCCYDHVI+T+HK+VLSV+PYVCN
Sbjct 5353 LYSSPTTLQAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHVIATTHKMVLSVSPYVCN 5412
Query 5353 APGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIAT 5412
APGCDV+DVT+LYLGGMSYYC H+P SFPLCANG VFGLYKN C GS ++ +FN +AT
Sbjct 5413 APGCDVSDVTKLYLGGMSYYCNDHRPVCSFPLCANGLVFGLYKNMCTGSSSIMEFNRLAT 5472
Query 5413 CDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGK 5472
CDW+++GDY LANT TE LKLFAAETL+ATEE K SY IAT++E++ +REL L WEVGK
Sbjct 5473 CDWSDSGDYTLANTTTEPLKLFAAETLRATEEASKQSYAIATIKEIVGERELILVWEVGK 5532
Query 5473 PRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHT 5532
+PPLNRNYVFTGY +TKNSKVQ+GEY FE+ DY DAV Y+ +TTYKL VGD FVLTSH+
Sbjct 5533 SKPPLNRNYVFTGYHLTKNSKVQLGEYVFERIDYSDAVSYKSSTTYKLAVGDIFVLTSHS 5592
Query 5533 VMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHF 5592
V LSAPT+V QE Y++ITG+YPT+ + +EF+++V N+QK G KY T+QGPPGTGKSHF
Sbjct 5593 VATLSAPTIVNQERYLKITGIYPTITVPEEFANHVVNFQKAGFSKYVTVQGPPGTGKSHF 5652
Query 5593 AIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNST 5652
AIGLA+YYP+ARIVYTACSHAAVDALC KA KYL I KCSRIIPA+ARVEC+D+FKVN T
Sbjct 5653 AIGLAIYYPTARIVYTACSHAAVDALCAKAFKYLNIAKCSRIIPAKARVECYDRFKVNDT 5712
Query 5653 LEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTL 5712
QY+F TVNALPE + DI+V DE+SM TNYDLS++N+R++AKH VY+GDPAQLPAPRTL
Sbjct 5713 NAQYLFSTVNALPEISVDILVVDEVSMCTNYDLSIINSRVKAKHIVYVGDPAQLPAPRTL 5772
Query 5713 LTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQC 5772
LT+GTLEPE FNSV RLM +GPD+FL C RCP EIV+TVSALVY+NKL A KD S QC
Sbjct 5773 LTRGTLEPENFNSVTRLMCNLGPDIFLSVCYRCPKEIVNTVSALVYNNKLSAKKDASGQC 5832
Query 5773 FKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQ 5832
FK+ +KG +THD SSAINRPQ+ V+ F+ NP W KAVFISPYNSQNAVA +LGL TQ
Sbjct 5833 FKILFKGSVTHDASSAINRPQLNFVKTFIAANPNWSKAVFISPYNSQNAVARSMLGLTTQ 5892
Query 5833 TVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLE 5892
TVDSSQGSEY YVIF QT +TAH+ N+NRFNVA+TRA+ GILC+M+ + L+D L+F L
Sbjct 5893 TVDSSQGSEYPYVIFCQTADTAHANNLNRFNVAVTRAQKGILCVMTSQVLFDSLEFAELS 5952
Query 5893 IPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFK-TEGLCVDIPGIPKDM 5951
+ N LQ++ VTGLFKDCS+ GL P APT+LSVD K+K T+ LCV++ I ++
Sbjct 5953 L---NNYKLQSQIVTGLFKDCSREDVGLPPAYAPTYLSVDAKYKTTDELCVNL-NITPNV 6008
Query 5952 TYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQL 6011
TY R+IS MGFK++ + GYP +FITR+EAIR VR+WIGFDVEG HA+R+A GTN+PLQL
Sbjct 6009 TYSRVISRMGFKLDATIPGYPKLFITRDEAIRQVRSWIGFDVEGAHASRNACGTNVPLQL 6068
Query 6012 GFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQM 6071
GFSTGVN V P G VDTE + T ++A+PPPG+QFKHL+PLM KG W +VR +IVQM
Sbjct 6069 GFSTGVNFVVQPVGVVDTEWGSMLTTISARPPPGEQFKHLVPLMNKGATWPIVRRRIVQM 6128
Query 6072 LSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNH 6131
LSDTL LSD FV WAHGFELTS YF KIG E+ CC+C +RA+ FS+ +YACW+H
Sbjct 6129 LSDTLDKLSDYCTFVCWAHGFELTSASYFCKIGKEQRCCMCSRRASTFSSPLQSYACWSH 6188
Query 6132 SVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKR 6191
S G+DYVYNPF +DVQQWG+ GNL +NHD++C +H AHVAS DAIMTRCLA+++CF++R
Sbjct 6189 SSGYDYVYNPFFVDVQQWGYVGNLATNHDRYCGIHAGAHVASSDAIMTRCLAIYDCFIER 6248
Query 6192 VDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWK 6251
VDW V YP I E ++NS CR V+ VV+SA+L+ KF ++DIGNPK I + + VEW
Sbjct 6249 VDWDVTYPYISHEQKLNSCCRTVERNVVRSAVLSGKFDKIYDIGNPKGIPIISEP-VEWH 6307
Query 6252 FYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNL 6311
FYDAQP S+K K LFY+ F DG+CLFWNCNV +YP+NA+VCRFDTRV S
Sbjct 6308 FYDAQPLSNKVKK---LFYTDDVAKQ-FEDGLCLFWNCNVSKYPSNAVVCRFDTRVHSEF 6363
Query 6312 NLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHG-KQVVSDIDYVPL 6370
NLPGC+GGSLYVNKHAFHTPA+D +AF +LK LPFFYYS +PCE HG ++ DIDYVPL
Sbjct 6364 NLPGCNGGSLYVNKHAFHTPAYDINAFRDLKPLPFFYYSTTPCEVHGSGNMLEDIDYVPL 6423
Query 6371 KSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQS 6430
KSA CIT CNLGGAVCR HA EYR Y++AYN++ +AGF LW+YK FD YNLW+TF ++Q
Sbjct 6424 KSAVCITACNLGGAVCRKHAAEYRDYMEAYNIVSAAGFRLWVYKTFDIYNLWSTFVKVQG 6483
Query 6431 LENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKR 6490
LEN+A+NV+ +GHF G GE PV+++N+ ++TK DV IF+N+T LP NVAFEL+AKR
Sbjct 6484 LENIAFNVIKQGHFTGVDGELPVAVVNDKIFTKNGTDDVCIFKNETALPTNVAFELYAKR 6543
Query 6491 NIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTV 6550
++ P++ +L NL VD+ N V+WDY R +TIGVC TDI +L +
Sbjct 6544 AVRSHPDLNLLRNLEVDVCYNFVLWDYDRNNIYGTTTIGVCKYTDI------DVNPNLNM 6597
Query 6551 LFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKT--QFNYF 6608
FD R +G ++ F + NGVLI++ +K GP A NG L K F +
Sbjct 6598 CFDIRDKGSLERFMSMPNGVLISDRKIKNYPCIIGPKHAYFNGAILRNIDAKQPITFYLY 6657
Query 6609 KKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGD 6668
KKV+ +T++T R + DF + ME DFL L D FI++Y LE YAFEH+VYGD
Sbjct 6658 KKVNNEFVSFSDTFYTCGRTVNDFTALTPMEEDFLVLDSDVFIKKYSLEDYAFEHVVYGD 6717
Query 6669 FSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLL 6728
FSH LGGLHL+IGL K+ +D + +E+ + +TV NYFITD+ T S K VCSVIDL L
Sbjct 6718 FSHTTLGGLHLLIGLYKKMRDGHILMEEMLKDRATVHNYFITDSNTASYKAVCSVIDLRL 6777
Query 6729 DDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPN 6788
DDFV IIK DL V+SKVVKV ID I FMLWCKDG V+TFYP+LQA+ W+PG+ MP+
Sbjct 6778 DDFVNIIKEMDLDVVSKVVKVPIDLTMIEFMLWCKDGKVQTFYPRLQATNDWKPGLTMPS 6837
Query 6789 LYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAG 6848
L+K+Q+M LE C L NY ++ +P G+ MNVAKY QLCQYLNT TLAVP NMRVIHFGAG
Sbjct 6838 LFKVQQMNLEPCLLANYKQSIPMPNGVHMNVAKYMQLCQYLNTCTLAVPANMRVIHFGAG 6897
Query 6849 SDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYD 6908
+KGVAPGT+VLRQWLP +L+D+DLN+FVSDAD T+ GDC TVH + DL+ISDMYD
Sbjct 6898 CEKGVAPGTSVLRQWLPLDAVLIDNDLNEFVSDADITIFGDCVTVHVGQQVDLLISDMYD 6957
Query 6909 PRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAF 6968
P TK V + N +K FF YLC FIK LALGGS+A+KITEHSW+ADLYK+MG F++WT F
Sbjct 6958 PCTKAVGEVNQTKALFFVYLCNFIKNNLALGGSVAIKITEHSWSADLYKIMGRFAYWTVF 7017
Query 6969 VTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLK 7028
TN NASSSE FLIG N+LG+ KE+IDG MHANYIFWRN+ P+ LS+YSLFD+S+FPLK
Sbjct 7018 CTNANASSSEGFLIGINFLGELKEEIDGNVMHANYIFWRNSTPMNLSTYSLFDLSRFPLK 7077
Query 7029 LRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
L+GT V+ LKE+QIN+++ SLL +G+L+IR+N+ + VS+D+LVN
Sbjct 7078 LKGTPVLQLKESQINELVISLLSQGKLLIRDNDTLNVSTDVLVN 7121
>sp|P0C6W5|R1AB_BCHK9 Replicase polyprotein 1ab OS=Bat coronavirus
HKU9 OX=694006 GN=rep PE=1 SV=1
Length=6930
Score = 8558 bits (22206), Expect = 0.0, Method: Composition-based stats.
Identities = 3366/7142 (47%), Positives = 4486/7142 (63%), Gaps = 364/7142 (5%)
Query 28 VRGFGDSVEEALSEAREHLKNGTCGLVELEKGV--LPQLEQPYVFIKRSDALSTNHG-HK 84
V G+ +EEAL A++ L+ LV + + P + V I S +TN G
Sbjct 29 VTGWDIPIEEALEYAKQQLRTPEPQLVFVPYYLSHAPGISGDRVVITDSIWYATNFGWQP 88
Query 85 VVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYR-NVLLRKNGNKGAGGHSYGIDLKSY 143
+ EL + DG++YGR G T GVL+P + I ++ +RK G G +S L +
Sbjct 89 IRELAMDKDGVRYGRGG-THGVLLPMQDPSFIMGDIDIQIRK---YGIGANSPPDVLPLW 144
Query 144 DLGDELGTD--PIEDYEQNW---NTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPL 198
D + G D P D+ N K G L+ + DNN G +
Sbjct 145 DGFSDPGPDVGPYLDFPDNCCPTKPKAKRGGDVYLSDQYG-------FDNN-----GILV 192
Query 199 DCIKDFLARAGKSMCTLSEQLDYIESKRGV--YCCRDHEHEIAWFTERSDKSYEHQTPFE 256
+ + L KS TL + L + R Y D ++A R Q+ F
Sbjct 193 EPVMKLLGVI-KSDFTLEQLLAALGKYRTEDGYDLPDGYVKVAIKVGRKAVPVLKQSIFT 251
Query 257 IKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGR-IRSVYPVASPQECNNM 315
+ + P + +P ++ V K G +G+ + +V + S NN
Sbjct 252 VVGVT-----EQLVPGYYYPFSTSSVVEH---TKPTRGGPVGKTVEAV--MLSLYGTNNY 301
Query 316 HLST---LMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYLPTNAVVKMPCPA 372
+ +T +KC++CD W + CG E + ++C + V+K C
Sbjct 302 NPATPVARLKCSYCDYYGWTPLKDIGTVNCLCGAE---FQLTSSCVDAESAGVIKPGCVM 358
Query 373 CQDPEIGPEHSVADYHNHSNIETRLRKGGRTRC-FGGCVFAYVGCYNKRAYWVPRASADI 431
D G RL G RT FGG +++ +G N WVPRA + +
Sbjct 359 LLDKSPG---------------MRLIPGNRTYVSFGGAIWSPIGKVNGVTVWVPRAYSIV 403
Query 432 GSGHTGITGD-NVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSA-FID 489
H+G G + +N++L+E L I + D N A +A+ T A +
Sbjct 404 AGEHSGAVGSGDTVAINKELVEYLIE---GIRVDADTLDNPTCATFIANLDCDTKAPVVH 460
Query 490 TIKSLDYKSFKTIVESCGNYKVTKG-KPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIF 548
T++SL C K+ G KP+ + + L + Q A ++
Sbjct 461 TVESLQ--------GLCLANKIMLGDKPLP----TDEFHPFIVGL-AYHVQRACWYGALA 507
Query 549 ARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY-VTGGLVQ 607
+RT +A D R + ++ VY + + AY V +
Sbjct 508 SRTFEA----FRDFVRTEEERFAQFFGKVCAPINGCVYLAYTTGRVTLFSAYQVLNTAIA 563
Query 608 QTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVA 667
++ + V+ L+PI EW+ K+S E L L F +VKG+ Q
Sbjct 564 KSKDAFGGVAAIVVDMLKPILEWVLKKMSIAKGAWLPYAEGLLALFKAQFTVVKGKFQFL 623
Query 668 SDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQCIRGKEQL 727
++ D++ + + V AG K+ +L G + KG+ + ++L
Sbjct 624 RASLNSKCHSLCDLLTTIMSKLLTSVKWAGCKVDALYTGTYYYFSRKGVLTEVQLCAKRL 683
Query 728 QLLM-PLKAPKEVTFLEGDSH-DTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCV 785
LL+ P + EV L+GD LT E+ G LE + D + GT V +
Sbjct 684 GLLLTPKQQKMEVEVLDGDFDAPVTLTDLELEECTGVLEEVFGASDV---KLVKGTLVSL 740
Query 786 NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFE 845
+ + +D Y + G FRL+GG + VTFG++ V + V +++
Sbjct 741 ASKLFVRTEDGFLYRYVKSG-GVLGKAFRLRGGG-VSKVTFGDEEVHTIPNTVTVNFSYD 798
Query 846 LDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTN-----MGIDLDE 900
+ E +D +L++ + + VE GT++ + ACVV +AV + L DL ++ I+L++
Sbjct 799 VCEGLDAILDKVMAPFQVEEGTKLEDLACVVQKAVYERLS---DLFSDCPAELRPINLED 855
Query 901 WSVATFYLFDDAGEENFSSRMYCSF---YPPDEEEEDDAECEEEEIDETCEHEYGTEDDY 957
+ + +++ E+ MY S P D+E DD I++T E ++D +
Sbjct 856 FLTSECFVYSKDYEKILMPEMYFSLEDAVPVDDEMVDD-------IEDTVEQASDSDDQW 908
Query 958 QGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVA 1017
G +E + D+T + ++ GY K+ ++V
Sbjct 909 LG----------------DEGAEDCDNTIQDVDVATSMTTPC--------GYTKIAEHVY 944
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
IKC DIV+EA++ + V+VNAAN++L HGGGVAGALN+ATN AMQKES +YIK NG L
Sbjct 945 IKCADIVQEARNYSYAVLVNAANVNLHHGGGVAGALNRATNNAMQKESSEYIKANGSLQP 1004
Query 1078 GGSCLLSGHNLAKK-CLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKP 1136
GG LLS H LA LHVVGP+ G+D+ LL A Y + D +L PL+SAGIFG
Sbjct 1005 GGHVLLSSHGLASHGILHVVGPDKRLGQDLALLDAVYAAYTGFDSVLTPLVSAGIFGFTV 1064
Query 1137 LQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKS 1196
+SL V+ V Y+ V D+ LYE+ + D P+ E + +E
Sbjct 1065 EESLCSLVKNVACTTYVVVYDRQLYERALATSFDVPGPQSSVQHVPAIDWAEAVEVQESI 1124
Query 1197 VVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLE 1256
V Q + + L ET ++ + + D ++ +R
Sbjct 1125 VDQVETPSLGAVDTVDSNADSGLNETARSPENVV--GSVPDDVVADVESCVRD------- 1175
Query 1257 KDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLE 1316
++ + +KKV D+ Q T+E
Sbjct 1176 -------------------------------LVRQVVKKVKRDKRPPPIVPQ----QTVE 1200
Query 1317 EAKTALKKCKSAFYVLPSEAPNA---KEEILGTVSWNLREMLAHAEETRKLMPICMDVRA 1373
+ P E + ++ VS + M+ +E L+P+ +D A
Sbjct 1201 QQ--------------PQEISSPGDCNTVLVDVVSMSFSAMVNFGKEKGLLIPVVIDYPA 1246
Query 1374 IMATIQRKYKGIKIQEGIVDY-GVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHG 1432
+ ++R +EG+ G F+ Y+ +P+ + LNSL PL+ +P G++ +G
Sbjct 1247 FLKVLKR----FSPKEGLFSSNGYEFYGYSRDKPLHEVSKDLNSLGRPLIMIPFGFIVNG 1302
Query 1433 FNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLT---SSSKTSEEHFVETVSLAGSYRD 1489
L +A MR L P V V S +V Y Y S T+ + FV + L G+ RD
Sbjct 1303 QTLAVSAVSMRGLTVPHTVVVPSESSVPLYRAYFNGVFSGDTTAVQDFVVDILLNGA-RD 1361
Query 1490 WSYSGQRTELGVE------FLKRGDKIVYHTLESPVEFHLDGEVL----SLDKLKSLLSL 1539
W +T V+ KRG+ Y + + + G+V+ ++ K ++ L
Sbjct 1362 WDV--LQTTCTVDRKVYKTICKRGN--TYLCFDDTNLYAITGDVVLKFATVSKARAYLET 1417
Query 1540 REVKT---IKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFF 1596
+ IKV TTVD N T LV + +Y Q G + DG D + P EG +
Sbjct 1418 KLCAPEPLIKVLTTVDGINYSTVLVSTAQSYRAQIGTVFCDGHDWSNKNPMPTDEGTHLY 1477
Query 1597 VLPSDDTLRSEAF-EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSS 1655
+ + A EYY D + + R MS + W + V G + D+NCYL+
Sbjct 1478 KQDNFSSAEVTAIREYYGVDDSNIIARAMSIRKTVQTWPYTVVDGRVLLAQRDSNCYLNV 1537
Query 1656 VLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQH 1715
+ LQ ++V F+ P + AY + G+ +++A T G D ++ +L H
Sbjct 1538 AISLLQDIDVSFSTPWVCRAYDALKGGNPLPMAEVLIALGKATPGVSDDAHMVLSAVLNH 1597
Query 1716 ANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLV 1775
+ +A+RV+ VC+HCG TG +A + G++ D+L VS+ C CGR A +Y+
Sbjct 1598 GTV-TARRVMQTVCEHCGVSQMVFTGTDACTFYGSVVLDDLYAPVSVVCQCGRPAIRYVS 1656
Query 1776 QQESSFVMMSAPPAEYKLQ-QGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMS 1834
+Q+S +++MS P + L G + A + G GHY + + D + S
Sbjct 1657 EQKSPWLLMSCTPTQVPLDTSGIWKTAIVFRGPVTAGHYMYAVNGTLISVYDANTRRRTS 1716
Query 1835 EYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPT 1894
+ K P TD+ Y TS+T+ K +Y LDGV T I+P Y K+ + Y+T PI++V
Sbjct 1717 DLKLPATDILYGPTSFTSDSKVETYYLDGVKRTTIDPDFSKYVKRGDYYFTTAPIEVV-A 1775
Query 1895 QPLPNASFDNFKLT-CSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYS 1953
P S+D F L+ C N + A+ N+ TK +L +T +P++ GDVVAI +
Sbjct 1776 APKLVTSYDGFYLSSCQNPQLAESFNKAINATKTGPMKL-LTMYPNVAGDVVAISDDNVV 1834
Query 1954 ASFKKGAKLLHKPIVWHINQATTKTTFKPNTWC-LRCLWSTKPVDTSNSFEVLAVEDTQG 2012
A G+ + KP+++ +PNTW L L ST V+T N+++VLAV+
Sbjct 1835 AH-PYGSLHMGKPVLFV---------TRPNTWKKLVPLLSTVVVNTPNTYDVLAVDPL-- 1882
Query 2013 MDNLACESQQPTSEEVVENPTIQKEVIEC-DVKTTEVVGNVILKPSDEG-VKVTQELGHE 2070
P + E E P K I +K T V+ P ++G + +E
Sbjct 1883 ----------PVNNETSEEPISVKAPIPLYGLKATMVLNGTTYVPGNKGHLLCLKEFTLT 1932
Query 2071 DLMAAYVENTS-ITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAIT 2129
DL YVE + K + LS LGL+ + +N + + AY
Sbjct 1933 DLQTFYVEGVQPFVLLKASHLSKVLGLRV--SDSSLHVNHLSKGVVYAYA---------- 1980
Query 2130 TSNCAKRLAQRVFNNYMPYVFTL-LFQLCTFTKSTNS------------RIRASLPTTIA 2176
A RL RV + + + T + + F +STN ++ +
Sbjct 1981 ----ATRLTTRVTTSLLGGLVTRSVRKTADFVRSTNPGSKCVGLLCLFYQLFMRFWLLVK 2036
Query 2177 KNSVKSVAKL-CLDAG-------INYVK-------SPKFSKLFTIAMWLLLLSICLGSLI 2221
K + V+ + + G +NY++ + KL +++ + CL
Sbjct 2037 KPPIVKVSGIIAYNTGCGVTTCVLNYLRSRCGNISWSRLLKLLRYMLYIWFVWTCLT--- 2093
Query 2222 CVTAAFGVLLSNFGAPSYCNGVRE--LYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYP 2279
GV LS APS + + + ++ + +C++G+DSLD YP
Sbjct 2094 ----ICGVWLSEPYAPSLVTRFKYFLGIVMPCDYVLVNETGTGWLHHLCMAGMDSLD-YP 2148
Query 2280 ALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2339
AL Q S + T + + E AY+L+T ++G+ A++ + Y + NS
Sbjct 2149 ALRMQQHRYGS-PYNYTYILMLLEAFFAYLLYTPALPIVGILAVLHLIVLYLPIP-LGNS 2206
Query 2340 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2399
WL+ F+ I+++ P ++M+RMYI A + +K ++H+ GC + C+MCYK+N A R+E
Sbjct 2207 WLVVFLYYIIRLVPFTSMLRMYIVIAFLWLCYKGFLHVRYGCNNVACLMCYKKNVAKRIE 2266
Query 2400 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPIN 2459
C+T+VNG+KR FYV ANGG FC HNWNC++CDT+ STFI +VA DLS QFKRPI
Sbjct 2267 CSTVVNGVKRMFYVNANGGTHFCTKHNWNCVSCDTYTVDSTFICRQVALDLSAQFKRPII 2326
Query 2460 PTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLP-INVI 2518
TD++ Y V SV V+NG ++ YF+ GQ++YER P+ F N+ L + KG+ P NV+
Sbjct 2327 HTDEAYYEVTSVEVRNGYVYCYFESDGQRSYERFPMDAFTNVSKLHYSELKGAAPAFNVL 2386
Query 2519 VFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSAT 2578
VFD ++ +E+A K+A++YY+QL C+PILL+D+ +V VGD ++ MF+AY +
Sbjct 2387 VFDATNRIEENAVKTAAIYYAQLACKPILLVDKRMVGVVGDDATIARAMFEAYAQNYLLK 2446
Query 2579 FSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVD--TDVDTKDVIECLKLSH 2636
+S+ M+K+K L +TA +++ G+ ++ VL FV + R D +DVDT D++ C++L H
Sbjct 2447 YSIAMDKVKHLYSTALQQISSGMTVESVLKVFVGSTRAEAKDLESDVDTNDLVSCIRLCH 2506
Query 2637 HSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYM 2696
E T DS NN + TY K + ++ ++G + NA+++NA +AK V+LIW D++
Sbjct 2507 QEGWEWTTDSWNNLVPTYIKQDTLSTLEVGQFMTANAKYVNANIAKGAAVNLIWRYADFI 2566
Query 2697 SLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGG--KIVSTCFKLMLKAT 2754
LSE +R+Q++ AA+K + +T ++ + V + T + GG +IVS L+
Sbjct 2567 KLSESMRRQLKVAARKTGLNLLVTTSSLKADVPCMVTPFKIIGGHRRIVSWRRVLIHVFM 2626
Query 2755 LLCVLA---ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGF 2811
LL VL YI+ P+ ++ +K I + V RDI S D CFANK + F
Sbjct 2627 LLVVLNPQWFTPWYIMRPIEY---------NVVDFKVIDNAVIRDITSADQCFANKFSAF 2677
Query 2812 DAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGN 2871
+ W+S R GSY N + CP+V +++ +G +VPGLP LR + L + AVG+
Sbjct 2678 ENWYSNRYGSYVNSRGCPMVVGVVSDIVGSLVPGLPARFLR-VGTTLLPLVNYGLGAVGS 2736
Query 2872 ICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRY 2931
+CYTP I Y F TSACVLAA CT+F A G+ +PYC D L++ + Y L+P Y
Sbjct 2737 VCYTPHYAINYDVFDTSACVLAATCTLFSSASGERMPYCADAALIQNASRYDMLKPHVMY 2796
Query 2932 VLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRA 2990
+ S I+FP V +V T EYC+ G C+ SE G+C+S RWV+NN ++R
Sbjct 2797 PFYEHSGYIRFPEVIS-AGVHIVRTMAMEYCKVGRCDVSEAGLCMSLQPRWVVNNAYFRQ 2855
Query 2991 LSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGE 3050
SGV+CG A +L N+ P+ PVGA+D++ S++ G ++A++V+ + YY ++FRR FG+
Sbjct 2856 QSGVYCGTSAFDLFMNMLLPIFTPVGAVDITTSILMGALLAVVVSMSLYYLLRFRRAFGD 2915
Query 3051 YNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFS 3110
Y+ V+ N L F+++ +LCL Y LP +Y++ +LY T YF +D++ + H+ + MF+
Sbjct 2916 YSGVIFTNILAFVLNVIVLCLEGPYPMLPSIYAMVFLYATCYFGSDIACMMHVSFLIMFA 2975
Query 3111 PIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKL 3170
+VP W+T +Y+ + +H WF + ++ V + F +F++AAL TF+L+KE++L+L
Sbjct 2976 GVVPLWVTVLYIVVVLSRHILWFASLCTKRTVQVGDLAFHSFQDAALQTFMLDKEVFLRL 3035
Query 3171 RSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPP 3230
+ E + Y +YLA+YNKYKY+SG +DT +YREAAC HL AL +SN G D +YQPP
Sbjct 3036 KRE--ISSDAYFKYLAMYNKYKYYSGPMDTAAYREAACSHLVMALEKYSNGGGDTIYQPP 3093
Query 3231 QTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDML 3290
+ S+ SA LQ+G +MA PSG VE C+V+V G+ TLNG+WLD+ V CPRHV+C+ +++
Sbjct 3094 RCSVASAALQAGLTRMAHPSGLVEPCLVKVNYGSMTLNGIWLDNFVICPRHVMCSRDELA 3153
Query 3291 NPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQ 3350
NP+Y L +R +N+ F V +RVIGH+M+ LL+L VD +NPKTP Y F+R+ GQ
Sbjct 3154 NPDYPRLSMRAANYDFHVSQNGHNIRVIGHTMEGSLLKLTVDVNNPKTPAYSFIRVSTGQ 3213
Query 3351 TFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTG 3410
S+LACY+G P+GVY C +R N T++ SFL GSCGS GF ++ V FCY+H +ELP G
Sbjct 3214 AMSLLACYDGLPTGVYTCTLRSNGTMRASFLCGSCGSPGFVMNGKEVQFCYLHQLELPNG 3273
Query 3411 VHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDF 3470
H GTD G FYGPF D+Q Q A D TIT+NVLAWLYAAV++G+ WFL + + + +F
Sbjct 3274 THTGTDFSGVFYGPFEDKQVPQLAAPDCTITVNVLAWLYAAVLSGENWFLTKSSISPAEF 3333
Query 3471 NLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDE 3530
N A+KY + +T + + +L PL+A+TGI+V M +ALK LL G GRTI+GS LEDE
Sbjct 3334 NNCAVKYMCQSVTSESLQVLQPLAAKTGISVERMLSALKVLLSAGFCGRTIMGSCSLEDE 3393
Query 3531 FTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLP 3590
TP+D+ RQ GV QGKF+ + + T W + F+ ++LIL+Q QW+ + LP
Sbjct 3394 HTPYDIGRQMLGVKLQGKFQSMFRWTLQWFAIIFVLTILILLQLAQWTFVGALPFTLLLP 3453
Query 3591 FTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMP---ASWVMRIMTWLELA 3647
+ LL+KHKH +L ++LLP AY+N Y P +++ + ++
Sbjct 3454 LIGFVAVCVGFVSLLIKHKHTYLTVYLLPVAMVTAYYNFQYTPEGVQGYLLSLYNYVNPG 3513
Query 3648 DTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQA 3707
+ G L ++ + A LL + R V DA R+W + + +Y + G+A A
Sbjct 3514 RIDVIGTDLLTMLIISVACTLL---SVRMVRTDAYSRIWYVCTAVGWLYNCWTGSADTVA 3570
Query 3708 ISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCC 3767
IS ++SV +NY+GV ++ A+ +V+V P + + +C+++ Y +GY C
Sbjct 3571 ISYLTFMVSVFTNYTGVACASLYAAQFMVWVLKFLDPTILLLYGRFRCVLVCYLLVGYLC 3630
Query 3768 CCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGK 3827
CYFG+F L+NR FR TLG Y+Y+VS+QE RYMNS GLLPP +S A LNIKL GIGG
Sbjct 3631 TCYFGVFNLINRLFRCTLGNYEYVVSSQELRYMNSHGLLPPTNSWQALMLNIKLAGIGGI 3690
Query 3828 PCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEK 3887
P +V+T+QS M+D+KCTSVVLLSVLQQLRVESSSKLWA CV+LHN+IL + TEAFE
Sbjct 3691 PIYRVSTIQSNMTDLKCTSVVLLSVLQQLRVESSSKLWALCVKLHNEILASNSPTEAFEA 3750
Query 3888 MVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVAN 3947
VSLLSVLLS+ GA++++ LC +L+N + LQA+ASEFS+L SY Y AQ+AY+ AVA
Sbjct 3751 FVSLLSVLLSLPGAINLDELCSSILENNSVLQAVASEFSNLSSYVDYENAQKAYDTAVAT 3810
Query 3948 GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQ 4007
G + LKK++NVAKS D+D A RKLE+M++ AMT MYKQAR+ED+R+KVT+AMQ
Sbjct 3811 GAPASTVNALKKAMNVAKSVLDKDVATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQ 3870
Query 4008 TMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFT 4067
TMLF M+R+LD+DAL+NI+NNAR+G VPL +IP T A KL++VVPD+ Y T T T
Sbjct 3871 TMLFNMIRRLDSDALSNILNNARNGVVPLGVIPRTAANKLLLVVPDFSVYTATITMPTLT 3930
Query 4068 YASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALR--ANSAVKLQNNELSPVA 4125
YA + W++ QV DAD K V ++I +NS NLAWPL+VTA R A S VKLQNNEL P
Sbjct 3931 YAGSAWDVMQVADADGKTVNATDITRENSVNLAWPLVVTAQRQQATSPVKLQNNELMPQT 3990
Query 4126 LRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTE 4185
+++M+ AG +QTAC D A+AYYN +K GR V+A+L+D L +A+ KS G G + E
Sbjct 3991 VKRMNVVAGVSQTACVTD-AVAYYNATKEGRHVMAILADTDGLAFAKVEKSTGDGFVILE 4049
Query 4186 LEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLS 4245
LEPPC+F+ DTPKGP +KYLYF KGL NL RG VLG+LA TVRL AG+ATEV +NS++LS
Sbjct 4050 LEPPCKFMVDTPKGPALKYLYFTKGLKNLCRGTVLGTLACTVRLHAGSATEVASNSSILS 4109
Query 4246 FCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCL 4305
C+F+VDP YKDYL +GG PI NCVKML HTGTG AIT P+AN+DQESFGGASCCL
Sbjct 4110 LCSFSVDPEATYKDYLDNGGSPIGNCVKMLTPHTGTGLAITAKPDANIDQESFGGASCCL 4169
Query 4306 YCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLRE 4365
YCRCHI+HP G C KGK+VQIP NDP+GF +RN VC VC MW+GYGC C LRE
Sbjct 4170 YCRCHIEHPGASGVCKYKGKFVQIPLVGVNDPIGFCIRNVVCAVCNMWQGYGCPCSSLRE 4229
Query 4366 PLMQSADASTFLNRVCGVS-AARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCR 4424
+Q+ D FLNRV G S ARL P G+G D+V RAFDI N KVAGF LK NCCR
Sbjct 4230 INLQARD-ECFLNRVRGTSGVARLVPLGSGVQPDIVLRAFDICNTKVAGFGLHLKNNCCR 4288
Query 4425 FQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHIS 4484
+QE D +G LDSYFVVKRHT SNY E+ Y +KDC VA HDFFKF ++G M PH+S
Sbjct 4289 YQELDADGTQLDSYFVVKRHTESNYLLEQRCYEKLKDCGVVARHDFFKFNIEGVMTPHVS 4348
Query 4485 RQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVY 4544
R+RLTKYTMADLVY+LRHFD NCDTLKEILV CC DYF++KDWYD VENPDI+RVY
Sbjct 4349 RERLTKYTMADLVYSLRHFDNNNCDTLKEILVLRGCCTADYFDRKDWYDPVENPDIIRVY 4408
Query 4545 ANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVD 4604
NLGE VR+++L V+ D+M + G++GVLTLDNQDLNG WYDFGDF++ G GV ++D
Sbjct 4409 HNLGETVRKAVLSAVKMADSMVEQGLIGVLTLDNQDLNGQWYDFGDFIEGPAGAGVAVMD 4468
Query 4605 SYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYH 4664
+YYSL MP+ T+T LAAE H+D D +KP WD+ KYD+T+ + LF +YFKYWD YH
Sbjct 4469 TYYSLAMPVYTMTNMLAAECHVDGDFSKPKRVWDICKYDYTQFKYSLFSKYFKYWDMQYH 4528
Query 4665 PNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVH 4724
PNC+ C DDRCILHCANFN+LFS V P TSFGPLV+KI+VDGVPFVVSTGYH+RELGVV
Sbjct 4529 PNCVACADDRCILHCANFNILFSMVLPNTSFGPLVQKIYVDGVPFVVSTGYHYRELGVVM 4588
Query 4725 NQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNF 4784
NQD+ H+ RLS +ELLVYAADPAMH A+ N L DKRT C SVAA+T V FQTVKPG F
Sbjct 4589 NQDIRQHAQRLSLRELLVYAADPAMHVAASNALADKRTVCMSVAAMTTGVTFQTVKPGQF 4648
Query 4785 NKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEV 4844
N+DFY+FAV GFFKEGS++ KHFF+AQDGNAAISDYDYYRYNLPTMCDI+QLLF +EV
Sbjct 4649 NEDFYNFAVKCGFFKEGSTISFKHFFYAQDGNAAISDYDYYRYNLPTMCDIKQLLFSLEV 4708
Query 4845 VDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNV 4904
VDKYFDCYDGGC+ A+QV+V N DKSAGFPFNK+GKARLYY+S+SY DQD LFAYTKRNV
Sbjct 4709 VDKYFDCYDGGCLQASQVVVANYDKSAGFPFNKFGKARLYYESLSYADQDELFAYTKRNV 4768
Query 4905 IPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFY 4964
+PTITQMNLKYAISAKNRARTVAGVSI STMTNRQFHQK+LKSIAA RGA+VVIGT+KFY
Sbjct 4769 LPTITQMNLKYAISAKNRARTVAGVSIASTMTNRQFHQKMLKSIAAARGASVVIGTTKFY 4828
Query 4965 GGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRL 5024
GGW+ ML+T+ VE PHLMGWDYPKCDRAMPN+LRI ASL+LARKH TCCN S RFYRL
Sbjct 4829 GGWNRMLRTLCEGVENPHLMGWDYPKCDRAMPNLLRIFASLILARKHATCCNASERFYRL 4888
Query 5025 ANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKI 5084
ANECAQVLSEMV+CGG YVKPGGTSSGD+TTAYANSVFNICQAV+AN+N LS DGNKI
Sbjct 4889 ANECAQVLSEMVLCGGGFYVKPGGTSSGDSTTAYANSVFNICQAVSANLNTFLSIDGNKI 4948
Query 5085 ADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGL 5144
YV+ LQ RLY +YR+ VD+E V ++Y YLRKHFSMMILSDD VVCYN++YA +G
Sbjct 4949 YTTYVQELQRRLYLGIYRSNTVDNELVLDYYNYLRKHFSMMILSDDGVVCYNADYAQKGY 5008
Query 5145 VASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPS 5204
VA I+ FK +LY+QNNVFMSE+KCW E D+TKGPHEFCSQHTMLV + VYLPYPDPS
Sbjct 5009 VADIQGFKELLYFQNNVFMSESKCWVEPDITKGPHEFCSQHTMLVDMKGEQVYLPYPDPS 5068
Query 5205 RILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDEL 5264
RILGAGCFVDD++KTDGTLM+ER+VSLAIDAYPLTKHP+ EY +VF YLQYI+KLH+EL
Sbjct 5069 RILGAGCFVDDLLKTDGTLMMERYVSLAIDAYPLTKHPDPEYQNVFWCYLQYIKKLHEEL 5128
Query 5265 TGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRP 5324
TGH+LD YSVML +DN S+YWE EFYE MY LQ+VG CV+CNSQTSLRCG CIRRP
Sbjct 5129 TGHLLDTYSVMLASDNASKYWEVEFYENMYMESATLQSVGTCVVCNSQTSLRCGGCIRRP 5188
Query 5325 FLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPL 5384
FLCCKCCYDHV+ST+HKLVLSV PYVCN P CDV DVTQLYLGGMSYYC+ H+PPISFPL
Sbjct 5189 FLCCKCCYDHVVSTTHKLVLSVTPYVCNNPSCDVADVTQLYLGGMSYYCRDHRPPISFPL 5248
Query 5385 CANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEE 5444
CANGQVFGLYKN C GS +V DFN++ATCDW+N+ DY+LANT TERLKLFAAETL+ATEE
Sbjct 5249 CANGQVFGLYKNICTGSPDVADFNSLATCDWSNSKDYVLANTATERLKLFAAETLRATEE 5308
Query 5445 TFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKG 5504
K +Y A V+EVLSDREL LSWE GK RPPLNRNYVFTG+ +TKNSKVQ+GEY FEKG
Sbjct 5309 NAKQAYASAVVKEVLSDRELVLSWETGKTRPPLNRNYVFTGFHITKNSKVQLGEYIFEKG 5368
Query 5505 DYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFS 5564
DYGD V YR +TTYKL VGDYFVLTSH+V PLS+PTL+PQE Y ++ GLYP +N+ + F+
Sbjct 5369 DYGDVVNYRSSTTYKLQVGDYFVLTSHSVQPLSSPTLLPQERYTKLVGLYPAMNVPESFA 5428
Query 5565 SNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALK 5624
SNV +YQ+VGM +Y+T+QGPPGTGKSH +IGLALYYPSA+IVYTACSHAAVDALCEKA K
Sbjct 5429 SNVVHYQRVGMSRYTTVQGPPGTGKSHLSIGLALYYPSAKIVYTACSHAAVDALCEKAHK 5488
Query 5625 YLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYD 5684
LPI++CSRI+PA+ARVECF KFKVN QYVF T+NALPETTADI+V DE+SM TNYD
Sbjct 5489 NLPINRCSRIVPAKARVECFSKFKVNDVGAQYVFSTINALPETTADILVVDEVSMCTNYD 5548
Query 5685 LSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRR 5744
LS++NAR+RAKH VY+GDPAQLPAPRTLLTKGTL PE+FNSVCRLM +GPD+FL TC R
Sbjct 5549 LSMINARVRAKHIVYVGDPAQLPAPRTLLTKGTLAPEHFNSVCRLMVAVGPDIFLATCYR 5608
Query 5745 CPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRN 5804
CP EIVDTVSALVYD KLKA+K + +C+K +YKG +THD SSAIN+PQ+G+V+EFL +N
Sbjct 5609 CPKEIVDTVSALVYDKKLKANKVTTGECYKCYYKGSVTHDSSSAINKPQLGLVKEFLIKN 5668
Query 5805 PAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNV 5864
P W+ AVFISPYNSQN+VA ++LGL TQTVDSSQGSE+DYVI+ QT++TAH+ NVNRFNV
Sbjct 5669 PKWQSAVFISPYNSQNSVARRMLGLQTQTVDSSQGSEFDYVIYCQTSDTAHALNVNRFNV 5728
Query 5865 AITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQ 5924
AITRAK GILC+MSD LY+ L+FT L++ +Q+E GLFKDC+K L P
Sbjct 5729 AITRAKKGILCVMSDSTLYESLEFTPLDVNDYVKPKMQSEVTVGLFKDCAKAE-PLGPAY 5787
Query 5925 APTHLSVDIKFK-TEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIR 5983
APT +SV+ KFK E LCV M Y RLIS MGFK + + GY +FITRE+AIR
Sbjct 5788 APTFVSVNDKFKLNESLCVHFDTTELQMPYNRLISKMGFKFDLNIPGYSKLFITREQAIR 5847
Query 5984 HVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPP 6043
VR W+GFDVEG HA +GTNLPLQ+GFSTGVN V P+GY+DTE+ + V +K P
Sbjct 5848 EVRGWVGFDVEGAHACGPNIGTNLPLQIGFSTGVNFVVTPSGYIDTESGSRLANVVSKAP 5907
Query 6044 PGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKI 6103
PGDQFKHLIPLM KG PW+VVR +IV+ML DTL G+SD V FV WAHGFELT++ YF K+
Sbjct 5908 PGDQFKHLIPLMRKGEPWSVVRKRIVEMLCDTLDGVSDTVTFVTWAHGFELTTLHYFAKV 5967
Query 6104 GPERTCCLCDKRATCFSTSSDTYACWNHS---VGFDYVYNPFMIDVQQWGFTGNLQSNHD 6160
GPER C +C +RAT FS+ Y+CW+H G D+VYNPF++DVQQWG+ GNLQ NHD
Sbjct 5968 GPERKCFMCPRRATLFSSVYGAYSCWSHHRHIGGADFVYNPFLVDVQQWGYVGNLQVNHD 6027
Query 6161 QHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVK 6220
C VH AHVASCDAIMTRCLA+H+CF V+W VEYPII +EL +N ACR VQ +V+K
Sbjct 6028 NVCDVHKGAHVASCDAIMTRCLAIHDCFCGEVNWDVEYPIIANELAINRACRSVQRVVLK 6087
Query 6221 SALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFT 6280
+A+ A ++DIGNPKAIK W FYD P +++L Y Y H D+F
Sbjct 6088 AAVKALHIETIYDIGNPKAIKVYGVNVNNWNFYDTNPV---VEGVKQLHYVYDVHRDQFK 6144
Query 6281 DGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTN 6340
DG+ +FWNCNVD YP NA+VCRFDTRVLS LNL GC+GGSLYVN+HAFHT AF+K+AF N
Sbjct 6145 DGLAMFWNCNVDCYPHNALVCRFDTRVLSKLNLAGCNGGSLYVNQHAFHTDAFNKNAFVN 6204
Query 6341 LKQLPFFYYSDSPCES---HGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYL 6397
LK LPFFYYSD+ CE+ VS++DYVPLKS CITRCNLGGAVC+ HA+EYR +L
Sbjct 6205 LKPLPFFYYSDTACENATGVSTNYVSEVDYVPLKSNVCITRCNLGGAVCKKHADEYRNFL 6264
Query 6398 DAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIIN 6457
++YN M+SAGF+LW+ K FD +NLW+TF +LQSLENVAYNV+ GHF AGE PV+I+N
Sbjct 6265 ESYNTMVSAGFTLWVDKTFDVFNLWSTFVKLQSLENVAYNVLKSGHFTAVAGELPVAILN 6324
Query 6458 NAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDY 6517
+ +Y K DG D +F N T LP NVAFELWAKR++ VPE+K+L NLGV N VIWDY
Sbjct 6325 DRLYIKEDGADKLLFTNNTCLPTNVAFELWAKRSVNVVPEVKLLRNLGVTCTYNLVIWDY 6384
Query 6518 KREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSV 6577
+ AP +T+G+CT TD+ K + VL DGR F +N + +
Sbjct 6385 ESNAPLVPNTVGICTYTDLTKLDDQ------VVLVDGRQLDAYSKFCQLKNAIYFSPSKP 6438
Query 6578 KGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQ 6637
K + ++GP AS+NGV + T F Y + DG Q + YFTQSR ++DF+PR+Q
Sbjct 6439 KCV-CTRGPTHASINGVVVEAPDRGTAFWYAMRKDGAFVQPTDGYFTQSRTVDDFQPRTQ 6497
Query 6638 METDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDF 6697
+E DFL+L F+ +Y L EHIVYG F G +GGLHL+IG +R + + L +E
Sbjct 6498 LEIDFLDLEQSCFLDKYDLHDLGLEHIVYGQFD-GTIGGLHLLIGAVRRKRTAHLVMETV 6556
Query 6698 IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEIS 6757
+ D TV +Y + D T SSK VCSV+D++LDDF+ +IK+QD SV+SKVV+ +D+
Sbjct 6557 LGTD-TVTSYAVIDQPTASSKQVCSVVDIILDDFIALIKAQDRSVVSKVVQCCLDFKVFR 6615
Query 6758 FMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMM 6817
FMLWCK G + TFYP+LQA Q W+PG +MP LYK+Q +LE C L NYG+ A +P G +M
Sbjct 6616 FMLWCKGGKISTFYPQLQAKQDWKPGYSMPALYKVQNAVLEPCLLHNYGQAARLPSGTLM 6675
Query 6818 NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND 6877
NVAKYTQLCQYLNT +LAVP MRV+HFGAGSDKGV PGTAVL+QWLP LVD+DL
Sbjct 6676 NVAKYTQLCQYLNTCSLAVPAKMRVMHFGAGSDKGVCPGTAVLKQWLPADAYLVDNDLCY 6735
Query 6878 FVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLA 6937
SDADST +G C T + NKWD I SDMYD RTK+ + +N SKEGFFTYL GFI+ KLA
Sbjct 6736 CASDADSTYVGSCETFFSVNKWDFIFSDMYDARTKNTSGDNTSKEGFFTYLTGFIRSKLA 6795
Query 6938 LGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGY 6997
LGGSIA+KITEHSW+ADLY +MGHF+WWT F T+VN+SSSEAFLIG NY+G +DG+
Sbjct 6796 LGGSIAIKITEHSWSADLYAIMGHFNWWTCFCTSVNSSSSEAFLIGVNYIGV-GALLDGW 6854
Query 6998 TMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLII 7057
MHANY+FWRN+ +QLSSYSL+D+ +FPL+L+GT VMSLKE+Q+N+++ +L+ GRLI+
Sbjct 6855 QMHANYVFWRNSTVMQLSSYSLYDLQRFPLRLKGTPVMSLKEDQLNELVLNLIRAGRLIV 6914
Query 7058 RE 7059
R+
Sbjct 6915 RD 6916
>sp|K9N7C7|R1AB_MERS1 Replicase polyprotein 1ab OS=Middle East
respiratory syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=rep PE=1 SV=1
Length=7078
Score = 8040 bits (20862), Expect = 0.0, Method: Composition-based stats.
Identities = 3048/6167 (49%), Positives = 4061/6167 (66%), Gaps = 244/6167 (4%)
Query 1090 KKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
++C V +L GE + + + E + + +A + A PL + ++V+
Sbjct 968 EECSEVEASDLEEGESECISETSTEQVDVSHEISDDEWAAAVDEAFPLDEAEDVTESVQE 1027
Query 1150 Q---VYIAVNDKALYEQVVMDYLDN---LKPRVEAPKQ----------------EEPPNT 1187
+ V + V D A + V+ D L + VE P Q E P
Sbjct 1028 EAQPVEVPVEDIA--QVVIADTLQETPVVSDTVEVPPQVVKLPSEPQTIQPEVKEVAPVY 1085
Query 1188 EDSKTEEKSVVQKPVDVKPK-------------IKACIDEVT-TTLEETKFLTNKLL--- 1230
E + +SV KP ++ K I C+ V ++ K +L
Sbjct 1086 EADTEQTQSVTVKPKRLRKKRNVDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNA 1145
Query 1231 ------LFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVIT------SGDITCVVIP 1278
I G + S+ ++ E ++ P VGD + + +I VV P
Sbjct 1146 ANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGP 1205
Query 1279 SKKAGGTTEMLSRALKKVPVDEYI-TTYPGQGCAG--------YTLEEAKTALKKCKSAF 1329
+A +LS+ K + + T G G Y + EAKT + ++
Sbjct 1206 DARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQ 1265
Query 1330 YVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQE 1389
V S + L LR + A++ + +C D A ++ K +
Sbjct 1266 DVYKSLTIVDIPQSLTFSYDGLRGAIRKAKDYGFTVFVCTDNSANTKVLRNKGVDYTKKF 1325
Query 1390 GIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPA 1449
VD GV+++ YTSK+ + I+ + N + +++MP+GYV+HG +L +A +R + P
Sbjct 1326 LTVD-GVQYYCYTSKDTLDDILQQANK-SVGIISMPLGYVSHGLDLIQAGSVVRRVNVPY 1383
Query 1450 VVSVSSPDAVTTYNGYLTSSSKT-SEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGD 1508
V +++ + ++ K E F++ V G Y W EL V+ L+
Sbjct 1384 VCLLANKEQEAIL---MSEDVKLNPSEDFIKHVRTNGGYNSWHLV--EGELLVQDLRLNK 1438
Query 1509 KI------------VYHTLESPVEFHLDGEVLSLDKLKSLLSLREVK--TIKVFTTVDNT 1554
+ V++ +++ F + +L ++ L R + TI+V TVD
Sbjct 1439 LLHWSDQTICYKDSVFYVVKNSTAFPFE----TLSACRAYLDSRTTQQLTIEVLVTVDGV 1494
Query 1555 NLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAF-EYYH 1613
N T +++ TY Q G + +GAD++ P G + ++ + ++A E Y
Sbjct 1495 NFRTVVLNNKNTYRSQLGCVFFNGADISDTIPDEKQNGHSLYLADNLTADETKALKELYG 1554
Query 1614 TLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLE-VKFNAPAL 1672
+D +FL R+ S KWK + S+K +DNNCYL++V++ L L+ +KF PAL
Sbjct 1555 PVDPTFLHRFYSLKAAVHKWKMVVCDKVRSLKLSDNNCYLNAVIMTLDLLKDIKFVIPAL 1614
Query 1673 QEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE-SAKRVLNVVCKH 1731
Q A+ + + GD+ +F ALI+AY N T G D + +L A L SA+ V C
Sbjct 1615 QHAFMKHKGGDSTDFIALIMAYGNCTFGAPDDASRLLHTVLAKAELCCSARMVWREWCNV 1674
Query 1732 CGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEY 1791
CG K L G++A Y+G + ++L+ ++ C CG + + +V+ + ++++S P E
Sbjct 1675 CGIKDVVLQGLKACCYVGVQTVEDLRARMTYVCQCGGERHRQIVEHTTPWLLLSGTPNEK 1734
Query 1792 KLQQGT---FLCANEYTG-NYQCGHYTHITAKETL-YRIDGAHLTKMSEYKGPVTDVFYK 1846
+ T F+ N + G GHY H K L + D ++K S++K VTDV +
Sbjct 1735 LVTTSTAPDFVAFNVFQGIETAVGHYVHARLKGGLILKFDSGTVSKTSDWKCKVTDVLFP 1794
Query 1847 ETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYT-EQPIDLVPTQPLPNASFDNF 1905
Y++ V Y LDG TE++P L +Y KD Y+T E P+ P L + + N
Sbjct 1795 GQKYSSDCNVVRYSLDGNFRTEVDPDLSAFYVKDGKYFTSEPPVTYSPATILAGSVYTNS 1854
Query 1906 KLTCSNTKFADD-----LNQMTGF--TKPASRELSVTFFPDLNGDVVAIDYRHYSASFKK 1958
L S+ + D N + GF +KP +++ + +F P +GDV+ ++ Y +K
Sbjct 1855 CLVSSDGQPGGDAISLSFNNLLGFDSSKPVTKKYTYSFLPKEDGDVLLAEFDTYDPIYKN 1914
Query 1959 GAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLAC 2018
GA KPI+W + K N LR ++ P++ N F L+VE T
Sbjct 1915 GAMYKGKPILWVNKASYDTNLNKFNRASLRQIFDVAPIELENKFTPLSVEST-------- 1966
Query 2019 ESQQPTSEEVVENPTIQKE--VIECD-VKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
P V+ +Q+E +++C + V NV D G V + L EDL
Sbjct 1967 ----PVEPPTVDVVALQQEMTIVKCKGLNKPFVKDNVSFVADDSGTPVVEYLSKEDLHTL 2022
Query 2076 YVE-NTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAI------ 2128
YV+ + + K N LS L L T+ + IN V S L L +A+
Sbjct 2023 YVDPKYQVIVLKDNVLSSMLRLHTVESGD---INVVAASGSLTRKVKLLFRASFYFKEFA 2079
Query 2129 --------TTSNCAKRLAQRV---------FNNYMPYVFTLLFQLCTFTKSTNSRIRASL 2171
+C K + + + +++ +F L + +K + ++ S
Sbjct 2080 TRTFTATTAVGSCIKSVVRHLGVTKGILTGCFSFVKMLFMLPLAYFSDSKLGTTEVKVSA 2139
Query 2172 PTT---IAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG 2228
T + N VK +D ++ ++ + + + L + L S+ +
Sbjct 2140 LKTAGVVTGNVVKQCCTAAVDLSMDKLRRVDWKSTLRLLLMLCTTMVLLSSVYHLYVFNQ 2199
Query 2229 VLLSN-------------------FGAPSYCNGVRELY-LNSSNVTTMDFCEG-SFPCSI 2267
VL S+ G S C+G+ Y NS +V T FC S C+
Sbjct 2200 VLSSDVMFEDAQGLKKFYKEVRAYLGISSACDGLASAYRANSFDVPT--FCANRSAMCNW 2257
Query 2268 CLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVF 2327
CL DS+ YPAL+ +Q +S Y L++ L A E LAYML+T F L L+ + F
Sbjct 2258 CLISQDSITHYPALKMVQTHLSHYVLNIDWLWFAFETGLAYMLYTSAFNWLLLAGTLHYF 2317
Query 2328 FGY------FASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGC 2381
F + S+ + S W I P++ +VRMY A + + K Y H+++GC
Sbjct 2318 FAQTSIFVDWRSYNYAVSSAFWLFTHI----PMAGLVRMYNLLACLWLLRKFYQHVINGC 2373
Query 2382 TSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTF 2441
+ C++CYKRNR TRVE +T+V G KR+FY+ ANGG FC+ HNWNC++CDT G+TF
Sbjct 2374 KDTACLLCYKRNRLTRVEASTVVCGGKRTFYITANGGISFCRRHNWNCVDCDTAGVGNTF 2433
Query 2442 ISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNL 2501
I +EVA DL+ +RPIN TD+S Y VDSV VK + + + GQ YER PL F NL
Sbjct 2434 ICEEVANDLTTALRRPINATDRSHYYVDSVTVKETVVQFNYRRDGQPFYERFPLCAFTNL 2493
Query 2502 DNLR----ANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDV 2557
D L+ T G N I++D + ES ++SA VYYSQ++C+ ILL+D +LV+ V
Sbjct 2494 DKLKFKEVCKTTTGIPEYNFIIYDSSDRGQESLARSACVYYSQVLCKSILLVDSSLVTSV 2553
Query 2558 GDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQG 2617
GDS+E++ KMFD++V++F + ++V +KL+ L++TA + +G VL+TF+ AAR
Sbjct 2554 GDSSEIATKMFDSFVNSFVSLYNVTRDKLEKLISTARDGVRRGDNFHSVLTTFIDAARGP 2613
Query 2618 V-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHI 2676
V++DV+T ++++ ++ +H D+++T +S NN++ +Y K ++++ DLG+ IDCNA +
Sbjct 2614 AGVESDVETNEIVDSVQYAHKHDIQITNESYNNYVPSYVKPDSVSTSDLGSLIDCNAASV 2673
Query 2677 NAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKIS 2736
N V ++ N + IWN YM LS+ L++QIR A +K N+ FRLT + R N+++ + +
Sbjct 2674 NQIVLRNSNGACIWNAAAYMKLSDALKRQIRIACRKCNLAFRLTTSKLRANDNILSVRFT 2733
Query 2737 LKG---------GKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYK 2787
+ K + AT++ L A++ Y+ +P ++ + Y + I+ +K
Sbjct 2734 ANKIVGGAPTWFNALRDFTLKGYVLATIIVFLCAVLMYLCLPTFSMVPVEFYEDRILDFK 2793
Query 2788 AIQDGVTRDIISTDDCFANKHAGFDAWFSQR-GGSYKNDKSCPVVAAIITREIGFIVPGL 2846
+ +G+ RD+ D CFANKH F W+ + GG Y N +CP+ A+I G +P +
Sbjct 2794 VLDNGIIRDVNPDDKCFANKHRSFTQWYHEHVGGVYDNSITCPLTVAVIAGVAGARIPDV 2853
Query 2847 PGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKP 2906
P T L +N + F+ RVF+ G++CYTP I Y F+ S C+L +ECT+F+DA G+
Sbjct 2854 PTT-LAWVNNQIIFFVSRVFANTGSVCYTPIDEIPYKSFSDSGCILPSECTMFRDAEGRM 2912
Query 2907 VPYCYDTNLLEGSISYSELRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDAEYCRHGT 2965
PYC+D +L G+ +YS++RP RY L DG++ I+FP E ++R+ T +YCR G+
Sbjct 2913 TPYCHDPTVLPGAFAYSQMRPHVRYDLYDGNMFIKFPEVVFESTLRITRTLSTQYCRFGS 2972
Query 2966 CERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVV 3025
CE ++ G+C++T+G W + N+H+ GV+CG D ++++ + L QP+ ++ S+V
Sbjct 2973 CEYAQEGVCITTNGSWAIFNDHHLNRPGVYCGSDFIDIVRRLAVSLFQPITYFQLTTSLV 3032
Query 3026 AGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVF 3085
G + +T YY K +R F +Y + +++ +C V + Y+
Sbjct 3033 LGIGLCAFLTLLFYYINKVKRAFADYTQCAVIAVVAAVLNSLCICFVASIPLCIVPYTAL 3092
Query 3086 YLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRK--RVM 3143
Y Y TFYFTN+ +F+ H+ W+ MF PIVP W+T +Y + +H W + +K V
Sbjct 3093 YYYATFYFTNEPAFIMHVSWYIMFGPIVPIWMTCVYTVAMCFRHFFWVLAYFSKKHVEVF 3152
Query 3144 FNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSY 3203
+G +F++AA F++NK+ Y LR+ L Y+R+L L+NKYKYFSGA++T +Y
Sbjct 3153 TDGKLNCSFQDAASNIFVINKDTYAALRNS--LTNDAYSRFLGLFNKYKYFSGAMETAAY 3210
Query 3204 REAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCG 3263
REAA CHLAKAL +S +G+D+LYQPP SITS VLQSG KM+ PSG VE CMVQVTCG
Sbjct 3211 REAAACHLAKALQTYSETGSDLLYQPPNCSITSGVLQSGLVKMSHPSGDVEACMVQVTCG 3270
Query 3264 TTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQ---AGNVQLRVIGH 3320
+ TLNGLWLD+TV+CPRHV+C A+ + +PNY+ LLI +NHSF VQ LRV+GH
Sbjct 3271 SMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGH 3330
Query 3321 SMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSF 3380
+MQ LL+L VD +NP TP Y F ++PG FSVLACYNG P+G + MRPN+TIKGSF
Sbjct 3331 AMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSF 3390
Query 3381 LNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTI 3440
L GSCGSVG+ + ++FCYMH MEL G H G+ +G YG F+D+Q Q TD
Sbjct 3391 LCGSCGSVGYTKEGSVINFCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYC 3450
Query 3441 TLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIA 3500
++NV+AWLYAA++NG WF+ T++ FN A+ + + L+ +TG+A
Sbjct 3451 SVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALANQFTEFVG--TQSVDMLAVKTGVA 3508
Query 3501 VLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWM 3560
+ + A+++L G G+ ILGST+LEDEFTP DV Q GV Q +K+ GT HW+
Sbjct 3509 IEQLLYAIQQLY-TGFQGKQILGSTMLEDEFTPEDVNMQIMGVVMQSGVRKVTYGTAHWL 3567
Query 3561 LLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPS 3620
T +++ +I++Q+T+++L+ +++E + A MLLVKHKH FL LFLLP
Sbjct 3568 FATLVSTYVIILQATKFTLWNYLFETIPTQLFPLLFVTMAFVMLLVKHKHTFLTLFLLPV 3627
Query 3621 LATVAYFNMVYMP----ASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTART 3676
+ Y N+VY P +S ++ + WL + + D +Y S ++L+++ R
Sbjct 3628 AICLTYANIVYEPTTPISSALIAVANWLAPTNAYMRTTH-TDIGVYISMSLVLVIVVKRL 3686
Query 3677 VYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIV 3736
+ L + + +Y G A I+ V ++TS+Y+ V + LA+
Sbjct 3687 YNPSLSNFALALCSGVMWLYTYSIGEA-SSPIAYLVFVTTLTSDYTITVFVTVNLAKVCT 3745
Query 3737 FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQE 3796
+ Y P L + ++ I+L+Y LG+ C CYFG+F LLN R +GVYD+ VSTQE
Sbjct 3746 YAIFAYSPQLTLVFPEVKMILLLYTCLGFMCTCYFGVFSLLNLKLRAPMGVYDFKVSTQE 3805
Query 3797 FRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQL 3856
FR+M + L P++S +A LN KL+GIGG PCIKVA +QSK++D+KCTSVVLLSVLQQL
Sbjct 3806 FRFMTANNLTAPRNSWEAMALNFKLIGIGGTPCIKVAAMQSKLTDLKCTSVVLLSVLQQL 3865
Query 3857 RVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRA 3916
+E++S+ WA CV+ HNDIL A D +EAFEK VSL + L++ G VD++ L ++ D +
Sbjct 3866 HLEANSRAWAFCVKCHNDILAATDPSEAFEKFVSLFATLMTFSGNVDLDALASDIFDTPS 3925
Query 3917 TLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQ 3975
LQA SEFS L ++A AQ+AY++A+ +GD S VLK L+K++N+AK+ +++D A+
Sbjct 3926 VLQATLSEFSHLATFAELEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAVA 3985
Query 3976 RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP 4035
RKLE+MADQAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+P
Sbjct 3986 RKLERMADQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIP 4045
Query 4036 LNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDN 4095
L++IPL + KL VV+PD+ + + YA ALW+I + + D++IV+ S++ +D+
Sbjct 4046 LSVIPLCASNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VDS 4104
Query 4096 SPNLAWPLIVTALRAN-SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKG 4154
+ NL WPL++ RA+ SAVKLQNNE+ P L+ M +AG QT C + ++LAYY +G
Sbjct 4105 NENLTWPLVLECTRASTSAVKLQNNEIKPSGLKTMVVSAGQEQTNC-NTSSLAYYEPVQG 4163
Query 4155 GRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNL 4214
+ ++ALLSD+ LKWAR DG ++ EL+PPC+F+ PKGP+++YLYF+K LNNL
Sbjct 4164 RKMLMALLSDNAYLKWARVEGKDGFVSV--ELQPPCKFLIAGPKGPEIRYLYFVKNLNNL 4221
Query 4215 NRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKM 4274
+RG VLG +AATVRLQAG+ TE +NS+VLS F VDP KAY D++ +GG P+TNCVKM
Sbjct 4222 HRGQVLGHIAATVRLQAGSNTEFASNSSVLSLVNFTVDPQKAYLDFVNAGGAPLTNCVKM 4281
Query 4275 LCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCA 4334
L TGTG AI+V PE+ DQE++GGAS CLYCR HI+HP+ G C KGK+VQIP C
Sbjct 4282 LTPKTGTGIAISVKPESTADQETYGGASVCLYCRAHIEHPDVSGVCKYKGKFVQIPAQCV 4341
Query 4335 NDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGV-SAARLTPCGT 4393
DPVGF L NT C VC W GYGC+CD LR+ + + S FL RV G AR+ PC +
Sbjct 4342 RDPVGFCLSNTPCNVCQYWIGYGCNCDSLRQAALPQSKDSNFLKRVRGSIVNARIEPCSS 4401
Query 4394 GTSTDVVYRAFDIYN--EKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQH 4451
G STDVV+RAFDI N KVAG K+ KTN CRF E D++G+ LDSYFVVKRHTM NY+
Sbjct 4402 GLSTDVVFRAFDICNYKAKVAGIGKYYKTNTCRFVELDDQGHHLDSYFVVKRHTMENYEL 4461
Query 4452 EETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTL 4511
E+ Y+L++DC AVA HDFF F VD PHI RQRLT+YTM DLVYALRHFD+ N + L
Sbjct 4462 EKHCYDLLRDCDAVAPHDFFIFDVDKVKTPHIVRQRLTEYTMMDLVYALRHFDQ-NSEVL 4520
Query 4512 KEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIV 4571
K ILV Y CCD YF K W+DFVENP ++ VY LGERVRQ++L TV+FCD M AG+V
Sbjct 4521 KAILVKYGCCDVTYFENKLWFDFVENPSVIGVYHKLGERVRQAILNTVKFCDHMVKAGLV 4580
Query 4572 GVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLA 4631
GVLTLDNQDLNG WYDFGDFV PG GV IVDSYYS LMP+L++T LAAE+H D D
Sbjct 4581 GVLTLDNQDLNGKWYDFGDFVITQPGSGVAIVDSYYSYLMPVLSMTDCLAAETHRDCDFN 4640
Query 4632 KPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFP 4691
KPLI+W L +YDFT+ ++ LF++YFKYWDQTYH NC+NC DDRC+LHCANFNVLF+ P
Sbjct 4641 KPLIEWPLTEYDFTDYKVQLFEKYFKYWDQTYHANCVNCTDDRCVLHCANFNVLFAMTMP 4700
Query 4692 PTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHA 4751
T FGP+VRKIFVDGVPFVVS GYH++ELG+V N DV+LH RLS KEL++YAADPAMH
Sbjct 4701 KTCFGPIVRKIFVDGVPFVVSCGYHYKELGLVMNMDVSLHRHRLSLKELMMYAADPAMHI 4760
Query 4752 ASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFF 4811
AS N LD RT+CFSVAALT + FQTV+PGNFN+DFYDF VSKGFFKEGSSV LKHFFF
Sbjct 4761 ASSNAFLDLRTSCFSVAALTTGLTFQTVRPGNFNQDFYDFVVSKGFFKEGSSVTLKHFFF 4820
Query 4812 AQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSA 4871
AQDGNAAI+DY+YY YNLPTMCDI+Q+LF +EVV+KYF+ YDGGC+NA++V+VNNLDKSA
Sbjct 4821 AQDGNAAITDYNYYSYNLPTMCDIKQMLFCMEVVNKYFEIYDGGCLNASEVVVNNLDKSA 4880
Query 4872 GFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSI 4931
G PFNK+GKAR+YY+SMSY++QD LFA TKRNVIPT+TQMNLKYAISAKNRARTVAGVSI
Sbjct 4881 GHPFNKFGKARVYYESMSYQEQDELFAMTKRNVIPTMTQMNLKYAISAKNRARTVAGVSI 4940
Query 4932 CSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKC 4991
STMTNRQ+HQK+LKS+AATRGAT VIGT+KFYGGW MLKT+Y DV+ PHLMGWDYPKC
Sbjct 4941 LSTMTNRQYHQKMLKSMAATRGATCVIGTTKFYGGWDFMLKTLYKDVDNPHLMGWDYPKC 5000
Query 4992 DRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSS 5051
DRAMPNM RI ASL+LARKH TCC RFYRLANECAQVLSE V+CGG YVKPGGTSS
Sbjct 5001 DRAMPNMCRIFASLILARKHGTCCTTRDRFYRLANECAQVLSEYVLCGGGYYVKPGGTSS 5060
Query 5052 GDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFV 5111
GDATTAYANSVFNI QA TANV+AL+ +GNKI DK V+++Q LY +YR+ D +FV
Sbjct 5061 GDATTAYANSVFNILQATTANVSALMGANGNKIVDKEVKDMQFDLYVNVYRSTSPDPKFV 5120
Query 5112 DEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTE 5171
D++YA+L KHFSMMILSDD VVCYNS+YAA+G +A I+NFK LYYQNNVFMSEAKCW E
Sbjct 5121 DKYYAFLNKHFSMMILSDDGVVCYNSDYAAKGYIAGIQNFKETLYYQNNVFMSEAKCWVE 5180
Query 5172 TDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSL 5231
TDL KGPHEFCSQHT+ +K GDD +LPYPDPSRIL AGCFVDDIVKTDGTLM+ERFVSL
Sbjct 5181 TDLKKGPHEFCSQHTLYIKDGDDGYFLPYPDPSRILSAGCFVDDIVKTDGTLMVERFVSL 5240
Query 5232 AIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYE 5291
AIDAYPLTKH + EY +VF +YLQYI KL+ +LTGHMLD YSVML DN++++WE FY
Sbjct 5241 AIDAYPLTKHEDIEYQNVFWVYLQYIEKLYKDLTGHMLDSYSVMLCGDNSAKFWEEAFYR 5300
Query 5292 AMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVC 5351
+Y+ T LQAVG+CV+C+SQTSLRCG CIRRPFLCCKCCYDHVI+T HK+VLSV+PYVC
Sbjct 5301 DLYSSPTTLQAVGSCVVCHSQTSLRCGTCIRRPFLCCKCCYDHVIATPHKMVLSVSPYVC 5360
Query 5352 NAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIA 5411
NAPGC V+DVT+LYLGGMSY+C H+P SFPLCANG VFGLYKN C GS ++ +FN +A
Sbjct 5361 NAPGCGVSDVTKLYLGGMSYFCVDHRPVCSFPLCANGLVFGLYKNMCTGSPSIVEFNRLA 5420
Query 5412 TCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVG 5471
TCDWT +GDY LANT TE LKLFAAETL+ATEE K SY IAT++E++ +R+L L WE G
Sbjct 5421 TCDWTESGDYTLANTTTEPLKLFAAETLRATEEASKQSYAIATIKEIVGERQLLLVWEAG 5480
Query 5472 KPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSH 5531
K +PPLNRNYVFTGY +TKNSKVQ+GEY FE+ DY DAV Y+ +TTYKL VGD FVLTSH
Sbjct 5481 KSKPPLNRNYVFTGYHITKNSKVQLGEYIFERIDYSDAVSYKSSTTYKLTVGDIFVLTSH 5540
Query 5532 TVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSH 5591
+V L+APT+V QE YV+ITGLYPT+ + +EF+S+VAN+QK G KY T+QGPPGTGKSH
Sbjct 5541 SVATLTAPTIVNQERYVKITGLYPTITVPEEFASHVANFQKSGYSKYVTVQGPPGTGKSH 5600
Query 5592 FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNS 5651
FAIGLA+YYP+AR+VYTACSHAAVDALCEKA KYL I KCSRIIPA+ARVEC+D+FKVN
Sbjct 5601 FAIGLAIYYPTARVVYTACSHAAVDALCEKAFKYLNIAKCSRIIPAKARVECYDRFKVNE 5660
Query 5652 TLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRT 5711
T QY+F T+NALPET+ADI+V DE+SM TNYDLS++NAR++AKH VY+GDPAQLPAPRT
Sbjct 5661 TNSQYLFSTINALPETSADILVVDEVSMCTNYDLSIINARIKAKHIVYVGDPAQLPAPRT 5720
Query 5712 LLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ 5771
LLT+GTLEPE FNSV RLM +GPD+FL C RCP EIV TVSALVY+NKL A K+ S Q
Sbjct 5721 LLTRGTLEPENFNSVTRLMCNLGPDIFLSMCYRCPKEIVSTVSALVYNNKLLAKKELSGQ 5780
Query 5772 CFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPT 5831
CFK+ YKG +THD SSAINRPQ+ V+ F+T NPAW KAVFISPYNSQNAVA +LGL T
Sbjct 5781 CFKILYKGNVTHDASSAINRPQLTFVKNFITANPAWSKAVFISPYNSQNAVARSMLGLTT 5840
Query 5832 QTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSL 5891
QTVDSSQGSEY YVIF QT +TAH+ N+NRFNVAITRA+ GILC+M+ + L++ L+FT L
Sbjct 5841 QTVDSSQGSEYQYVIFCQTADTAHANNINRFNVAITRAQKGILCVMTSQALFESLEFTEL 5900
Query 5892 EIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKT-EGLCVDIPGIPKD 5950
LQ++ VTGLFKDCS+ +GL P APT++SVD K+KT + LCV++ +P +
Sbjct 5901 SFTNY---KLQSQIVTGLFKDCSRETSGLSPAYAPTYVSVDDKYKTSDELCVNL-NLPAN 5956
Query 5951 MTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQ 6010
+ Y R+IS MGFK++ V GYP +FITREEA+R VR+WIGFDVEG HA+R+A GTN+PLQ
Sbjct 5957 VPYSRVISRMGFKLDATVPGYPKLFITREEAVRQVRSWIGFDVEGAHASRNACGTNVPLQ 6016
Query 6011 LGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQ 6070
LGFSTGVN V P G VDTE T + A+PPPG+QFKHL+PLM+KG W +VR +IVQ
Sbjct 6017 LGFSTGVNFVVQPVGVVDTEWGNMLTGIAARPPPGEQFKHLVPLMHKGAAWPIVRRRIVQ 6076
Query 6071 MLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWN 6130
MLSDTL LSD FV WAHGFELTS YF KIG E+ CC+C++RA +S+ +YACW
Sbjct 6077 MLSDTLDKLSDYCTFVCWAHGFELTSASYFCKIGKEQKCCMCNRRAAAYSSPLQSYACWT 6136
Query 6131 HSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVK 6190
HS G+DYVYNPF +DVQQWG+ GNL +NHD++C VH AHVAS DAIMTRCLA+H CF++
Sbjct 6137 HSCGYDYVYNPFFVDVQQWGYVGNLATNHDRYCSVHQGAHVASNDAIMTRCLAIHSCFIE 6196
Query 6191 RVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEW 6250
RVDW +EYP I E ++NS CR V+ VV++ALLA F ++DIGNPK I V V+W
Sbjct 6197 RVDWDIEYPYISHEKKLNSCCRIVERNVVRAALLAGSFDKVYDIGNPKGIPIVDDPVVDW 6256
Query 6251 KFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSN 6310
++DAQP + K+++LFY+ +F DG+CLFWNCNV +YP NAIVCRFDTRV S
Sbjct 6257 HYFDAQPLT---RKVQQLFYTED-MASRFADGLCLFWNCNVPKYPNNAIVCRFDTRVHSE 6312
Query 6311 LNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHG-KQVVSDIDYVP 6369
NLPGCDGGSLYVNKHAFHTPA+D SAF +LK LPFFYYS +PCE HG ++ DIDYVP
Sbjct 6313 FNLPGCDGGSLYVNKHAFHTPAYDVSAFRDLKPLPFFYYSTTPCEVHGNGSMIEDIDYVP 6372
Query 6370 LKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQ 6429
LKSA CIT CNLGGAVCR HA EYR+Y++AYN++ ++GF LW YK FD YNLW+TFT++Q
Sbjct 6373 LKSAVCITACNLGGAVCRKHATEYREYMEAYNLVSASGFRLWCYKTFDIYNLWSTFTKVQ 6432
Query 6430 SLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAK 6489
LEN+A+N V +GHF G GE PV+++N+ ++TK D+ +FENKTTLP N+AFEL+AK
Sbjct 6433 GLENIAFNFVKQGHFIGVEGELPVAVVNDKIFTKSGVNDICMFENKTTLPTNIAFELYAK 6492
Query 6490 RNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLT 6549
R ++ P+ K+L+NL DI V+WDY+R +TIGVC TDI S+L
Sbjct 6493 RAVRSHPDFKLLHNLQADICYKFVLWDYERSNIYGTATIGVCKYTDI------DVNSALN 6546
Query 6550 VLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQ---FN 6606
+ FD R G ++ F + N + I++ +K GP A NG + V Q F
Sbjct 6547 ICFDIRDNGSLEKFMSTPNAIFISDRKIKKYPCMVGPDYAYFNGAIIRDSDVVKQPVKFY 6606
Query 6607 YFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVY 6666
+KKV+ E +TQSR DF P S ME DFL D FI++Y LE YAFEH+VY
Sbjct 6607 LYKKVNNEFIDPTECIYTQSRSCSDFLPLSDMEKDFLSFDSDVFIKKYGLENYAFEHVVY 6666
Query 6667 GDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDL 6726
GDFSH LGGLHL+IGL K+ Q+ + +E+ + ST+ NYFIT+ T + K VCSVIDL
Sbjct 6667 GDFSHTTLGGLHLLIGLYKKQQEGHIIMEEMLKGSSTIHNYFITETNTAAFKAVCSVIDL 6726
Query 6727 LLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAM 6786
LDDFV I+KSQDL V+SKVVKV ID I FMLWCKDG V+TFYP+LQAS W+PG AM
Sbjct 6727 KLDDFVMILKSQDLGVVSKVVKVPIDLTMIEFMLWCKDGQVQTFYPRLQASADWKPGHAM 6786
Query 6787 PNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFG 6846
P+L+K+Q + LE+C+L NY ++ +P+G+ MN+AKY QLCQYLNT TLAVP NMRVIHFG
Sbjct 6787 PSLFKVQNVNLERCELANYKQSIPMPRGVHMNIAKYMQLCQYLNTCTLAVPANMRVIHFG 6846
Query 6847 AGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDM 6906
AGSDKG+APGT+VLRQWLPT +++D+DLN+FVSDAD TL GDC TV + DL+ISDM
Sbjct 6847 AGSDKGIAPGTSVLRQWLPTDAIIIDNDLNEFVSDADITLFGDCVTVRVGQQVDLVISDM 6906
Query 6907 YDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWT 6966
YDP TK+VT N+SK FFTYLC I LALGGS+A+KITEHSW+ +LY+LMG F+WWT
Sbjct 6907 YDPTTKNVTGSNESKALFFTYLCNLINNNLALGGSVAIKITEHSWSVELYELMGKFAWWT 6966
Query 6967 AFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFP 7026
F TN NASSSE FL+G NYLG KE IDG MHANYIFWRN+ P+ LS+YSLFD+SKF
Sbjct 6967 VFCTNANASSSEGFLLGINYLGTIKENIDGGAMHANYIFWRNSTPMNLSTYSLFDLSKFQ 7026
Query 7027 LKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
LKL+GT V+ LKE+QIN+++ SLL +G+L+IR+N+ + VS+D+LVN
Sbjct 7027 LKLKGTPVLQLKESQINELVISLLSQGKLLIRDNDTLSVSTDVLVNT 7073
Score = 1020 bits (2637), Expect = 0.0, Method: Composition-based stats.
Identities = 326/1332 (24%), Positives = 553/1332 (42%), Gaps = 170/1332 (13%)
Query 13 HVQLSLPVLQVRDV---LVRGFGDSVEEALSEAREHLKNGTCGL-VEL-EKGVLPQLEQP 67
HV L++P+ ++ L F D E A + L L V + G L P
Sbjct 28 HVSLTVPLCGSGNLVEKLSPWFMDG-ENAYEVVKAMLLKKEPLLYVPIRLAGHTRHLPGP 86
Query 68 YVFIKRSDALSTNHGHKVVELVAEM---DGIQYGRS--GITLGVLVPHVGETPIAYRNVL 122
V++ N +V +A +G G + G +G+ P+ E +N+L
Sbjct 87 RVYLVERLIACEN--PFMVNQLAYSSSANGSLVGTTLQGKPIGMFFPYDIELVTGKQNIL 144
Query 123 LRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAV 182
LRK G GG+ Y Y+ + + ++D+E + K+ L ++L GG V
Sbjct 145 LRKYGR---GGYHY--TPFHYERDNTSCPEWMDDFEADPKGKYAQN----LLKKLIGGDV 195
Query 183 TRYVDNNFCGPDGYPLDCIKDFLARAG-KSMCTLSEQLDYIESKRGVYCCRDHEHEIAWF 241
T VD CG DG P+ +A+ G + + + G +++ + + W
Sbjct 196 TP-VDQYMCGVDGKPISAYAFLMAKDGITKLADVEADVAARADDEGFITLKNNLYRLVWH 254
Query 242 TERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRIR 301
ER D Y Q+ F I S + D + P + F L K+ + PR + + +
Sbjct 255 VERKDVPYPKQSIFTINSVVQKDGVENTPPHY-FTLGCKILTLTPRNKWSGVSDLSLKQK 313
Query 302 SVYPVASPQE---CNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGP-TTC 357
+Y + ++ S ++C C SW T + ++ CG + +
Sbjct 314 LLYTFYGKESLENPTYIYHSAFIECGSCGNDSWLTGNAIQGFACGCGASYTANDVEVQSS 373
Query 358 GYLPTNAVVKMPCPACQDPEIGP--EHSVADYHNHSNIETRLRKGGR--TRCFGGCVFAY 413
G + NA++ CP + +HSVA ++ + + + T FGG +AY
Sbjct 374 GMIKPNALLCATCPFAKGDSCSSNCKHSVAQLVSYLSERCNVIADSKSFTLIFGGVAYAY 433
Query 414 VGCYNKRAYWVPRASAD-------IGSGHTGITGDNVETLNEDLLEILSRERVNINIVGD 466
GC Y+VPRA + I +G TG + N L + + ++N VG+
Sbjct 434 FGCEEGTMYFVPRAKSVVSRIGDSIFTGCTGSWNKVTQIANM----FLEQTQHSLNFVGE 489
Query 467 FHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIG-- 524
F +N+ V IL+ + + +K + + + + VT G + A N+G
Sbjct 490 FVVNDVVLAILSGTTTNVDKIRQLLKGVTLDKLRDYLADY-DVAVTAGPFMDNAINVGGT 548
Query 525 --QQRSVLTP---LCGFPSQAAGV------IRSIFARTLDAANHSIPDLQRAAVTILD-G 572
Q ++ P L G V + + TL HS+ L R +D G
Sbjct 549 GLQYAAITAPYVVLTGLGESFKKVATIPYKVCNSVKDTLTYYAHSV--LYRVFPYDMDSG 606
Query 573 ISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIE 632
+S S L D + SV ++ L +T ++S ++ + + + +
Sbjct 607 VSSFSELLFDCVDL-------SVASTYFLVRLLQDKTGDFMSTIITSCQTAVSKLLDTCF 659
Query 633 AKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQ 692
A FL D + + + + V + + VK +D++NK +++ +
Sbjct 660 EATEATFNFLLDLAGLFRIFLRNAYVYTSQGFVVVNGKVSTLVKQVLDLLNKGMQLLHTK 719
Query 693 VTIAGAKLRSLNLG--EVFIAQSKGLYRQCIRGK---EQLQLLMPLK-APKEVTFLEGDS 746
V+ AG+ + ++ E I S Y + K + L +++P + + K++ L+
Sbjct 720 VSWAGSNISAVIYSGRESLIFPSGTYYCVTTKAKSVQQDLDVILPGEFSKKQLGLLQPTD 779
Query 747 HDTVLTSEE----VVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDKE---QY 799
+ T ++ V G+LE + + IVG V ++ + + K+++ Y
Sbjct 780 NSTTVSVTVSSNMVETVVGQLEQ----TNMHSPDVIVGDYVIISEKLFVRSKEEDGFAFY 835
Query 800 CALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDERVDKVL-NEKC 858
A + G A +FRLKGGAP+K V FG D V EV ++V + + + +D +L +
Sbjct 836 PACTNGH-AVPTLFRLKGGAPVKKVAFGGDQVHEVAAVRSVTVEYNIHAVLDTLLASSSL 894
Query 859 SVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFS 918
+ V+ + EFA VV E V L + + DLD++ A Y F+ G+ ++S
Sbjct 895 RTFVVDKSLSIEEFADVVKEQVSDLLVKLLRGMPIPDFDLDDFIDAPCYCFNAEGDASWS 954
Query 919 SRMYCSFYPPD-----------EEEEDDAECEEEEIDETCEHEYGTEDDY------QGLP 961
S M S +P + + EE ++EC E E + + DD + P
Sbjct 955 STMIFSLHPVECDEECSEVEASDLEEGESECISETSTEQVDVSHEISDDEWAAAVDEAFP 1014
Query 962 LEFGASAETVRVEEEEEE--------------DWLDDTT---EQSEIEPEPEPTPEEP-- 1002
L+ A T V+EE + D L +T + E+ P+ P EP
Sbjct 1015 LD-EAEDVTESVQEEAQPVEVPVEDIAQVVIADTLQETPVVSDTVEVPPQVVKLPSEPQT 1073
Query 1003 ----------------------------------VNQFTGYLK--LTDNVAIKCVDIVKE 1026
V+ + + +T+ V I D ++
Sbjct 1074 IQPEVKEVAPVYEADTEQTQSVTVKPKRLRKKRNVDPLSNFEHKVITECVTIVLGDAIQV 1133
Query 1027 AQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGH 1086
A+ V+VNAAN HLKHGGG+AGA+N A+ GA+QKESD+YI GPL VG S LL GH
Sbjct 1134 AKCYGESVLVNAANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGH 1193
Query 1087 NLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQT 1146
+LAK LHVVGP+ A +D+ LL Y+ N+ +++ PL+SAGIFG KP S ++
Sbjct 1194 SLAKNILHVVGPDARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIRE 1253
Query 1147 VRTQVYIAVNDKALYEQVVMD--------YLDNLKPRVEAPKQE--EPPNTEDSKTEEKS 1196
+T+V + VN + +Y+ + + D L+ + K D+ K
Sbjct 1254 AKTRVLVVVNSQDVYKSLTIVDIPQSLTFSYDGLRGAIRKAKDYGFTVFVCTDNSANTKV 1313
Query 1197 VVQKPVDVKPKI 1208
+ K VD K
Sbjct 1314 LRNKGVDYTKKF 1325
>sp|P0C6X8|R1AB_CVM2 Replicase polyprotein 1ab OS=Murine coronavirus
(strain 2) OX=76344 GN=rep PE=3 SV=1
Length=7124
Score = 7844 bits (20354), Expect = 0.0, Method: Composition-based stats.
Identities = 2759/5657 (49%), Positives = 3664/5657 (65%), Gaps = 187/5657 (3%)
Query 1526 EVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIK 1585
+V S+ ++++LL + V TVD N + V +G+ G + DG +VTK++
Sbjct 1543 KVASVSQIRALL----ANKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR 1598
Query 1586 PHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIK 1645
H+GK FF A DE L +Y + L KW G + K
Sbjct 1599 CSAIHKGKVFFQYSGLSAADLVAVTDAFGFDEPQLLKYYNMLGMC-KWPVVVCGNYFAFK 1657
Query 1646 WADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDV 1705
++NNCY++ L LQ L +KF+ QEA+ R+G F +L+LA + E D
Sbjct 1658 QSNNNCYINVACLMLQHLSLKFHKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDS 1717
Query 1706 RETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCV 1765
+ M +L+ A+L A VCK CG K GV+AVM+ GTL +L G +I C
Sbjct 1718 TDFMRVVLREADLSGATCDFEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLAKGYTIACT 1776
Query 1766 CGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRI 1825
CG + Q F++ S P KL + AN +TG GHYTH+ K
Sbjct 1777 CGNKLV-HCTQLNVPFLICSNKPEGKKLPDDV-VAANIFTGG-SLGHYTHVKCKPKYQLY 1833
Query 1826 DGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYY 1884
D +++K+SE KG TD Y K T + K ++ LD V E P L YY + YY
Sbjct 1834 DACNVSKVSEAKGNFTDCLYLKNLKQTFSSKLTTFYLDDVKCVEYNPDLSQYYCESGKYY 1893
Query 1885 TEQPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNG 1942
T+ I T + NFKL A+ N GF E +T +P G
Sbjct 1894 TKPIIKAQFRTFEKVEGVYTNFKLV--GHSIAEKFNAKLGFDCNSPFTEYKITEWPTATG 1951
Query 1943 DVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF----KPNTWCLRCLWSTKPVDT 1998
DVV Y + + G KP++W ++ + + +P+ C ++ PVD
Sbjct 1952 DVVLASDDLYVSRYSGGCVTFGKPVIWLGHEEASLKSLTYFNRPSVVCEN-KFNVLPVDV 2010
Query 1999 SNSFE----VLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIECDV----------- 2043
S + AV T + A ++V + ++ +V+ +
Sbjct 2011 SEPTDKGPVPAAVLVTGALSGAATAPGTAKEQKVCASDSVVDQVVSGFLSDLSGATVDVK 2070
Query 2044 --------KTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALG 2095
K +V +V++ KV + L D+ ++ + NELS +
Sbjct 2071 EVKLNGVKKPIKVEDSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWMANELSRLVN 2130
Query 2096 LKTIATHGIAAINSVPWS--KILAYVKPFLGQAAITTSNCAKRLAQRVFNNY--MPYVFT 2151
T+ + V W KI+ K L + K + +V Y + + F
Sbjct 2131 SPTVREY-------VKWGMTKIVIPAKLVLLRDEKQEFVAPKVVKAKVIACYSAVKWFFL 2183
Query 2152 LLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLL 2211
F F + T +A K LC A N +++ ++ + +
Sbjct 2184 YCFSWIKFNTDN----KVIYTTEVAS---KLTFNLCCLAFKNALQTFNWNVVSRGFFLVA 2236
Query 2212 LLSICLGSLICVTAAF-------------------GVLLSNFGAPSYCNGVRELYLNSSN 2252
+ + + + + + FG + C+ LY S
Sbjct 2237 TVFLLWFNFLYANVILSDFYLPNIGFFPTFVGQIVAWVKTTFGIFTLCD----LYQVSDV 2292
Query 2253 VTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK--LDLTILGLAAEWVLAYML 2310
FC GS C +C SG D LD+Y A+ +Q + +++ L E V+ Y L
Sbjct 2293 GYRSSFCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRVSFDYISLFKLVVELVIGYSL 2352
Query 2311 FTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFASFY 2368
+T FY L MQ+ + F+ + W F + + M P ++R YI + Y
Sbjct 2353 YTVCFYPLFGLIGMQLLTTWLPEFFMLETMHWSARFFVFVANMLPAFTLLRFYIVVTAMY 2412
Query 2369 YIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWN 2428
I+ H+M GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WN
Sbjct 2413 KIFCLCRHVMYGCSRPGCLFCYKRNRSVRVKCSTVVGGTLRYYDVMANGGTGFCAKHQWN 2472
Query 2429 CLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQK 2488
CLNC F G+TFI+ E A DLS + KRP+NPTD + Y+V V ++ L++++ GQ+
Sbjct 2473 CLNCSAFGPGNTFITHEAAADLSKELKRPVNPTDSAYYLVTEVKQVGCSMRLFYERDGQR 2532
Query 2489 TYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILL 2548
Y+ S FV+++ L + KG +V+V + ++ D++ +A+V+Y+Q + +P+LL
Sbjct 2533 VYDDVSASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRPMLL 2590
Query 2549 LDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLS 2608
+++ L++ VS MFD YVD+ V + L + V AH+ L +GV L+ V+
Sbjct 2591 VEKKLITTANTGLSVSQTMFDLYVDSLLGVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMD 2650
Query 2609 TFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGA 2667
TF+ AR+ +D+DV+TK + + + + ++ ++ T +SCNN + TY K + + DLG
Sbjct 2651 TFIGCARRKCAIDSDVETKSITKSIMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGV 2710
Query 2668 CIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQV 2727
I NA+H+ A VAK+ NV+ IW+V + LS L+ ++R A K + +LT
Sbjct 2711 LIQNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEAN 2770
Query 2728 VNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYK 2787
V ++TT SLKGG + S + + L+C + V + +MP + + D +K
Sbjct 2771 VPILTTPFSLKGGAVFSKVLQWLFVVNLICFI---VLWALMPTYAVHKSDMQLPLYASFK 2827
Query 2788 AIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREIGFIVPG 2845
I +GV RD+ TD CFANK FD W+ G Y+N ++CPVV A+I ++IG+ +
Sbjct 2828 VIDNGVLRDVTVTDACFANKFIQFDQWYESTFGLVYYRNSRACPVVVAVIDQDIGYTLFN 2887
Query 2846 LPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGK 2905
+P VLR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G
Sbjct 2888 VPTKVLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGT 2946
Query 2906 PVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRHG 2964
P PYCY ++ + Y L P RY L + + I+FP EG VR+V T YCR G
Sbjct 2947 PHPYCYTEGIMHNASLYDSLAPHVRYNLANSNGYIRFPEVVSEGIVRIVRTRSMTYCRVG 3006
Query 2965 TCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASV 3024
CE +E G+C + + WVLNN +YRA+ G FCG +A +LI + LV+P+ ++AS
Sbjct 3007 LCEDAEEGVCFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASS 3066
Query 3025 VAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSV 3084
VAG I+AI+V A YY +K +R FG+Y VV N +++ ++F +L + Y L +Y+
Sbjct 3067 VAGAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYAC 3126
Query 3085 FYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMF 3144
FY Y T YF +++S + HLQW M+ I+P W IYV + H W F+ +++
Sbjct 3127 FYFYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFSYC--RKLGT 3184
Query 3145 NGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYR 3204
+ TFEE +L TF++ KE Y KL++ + +NRYL+LYNKY+YFSG +DT +YR
Sbjct 3185 EVRSDGTFEEMSLTTFMITKESYCKLKNS--VSDVAFNRYLSLYNKYRYFSGKMDTAAYR 3242
Query 3205 EAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCG 3263
EAAC LAKA+ F+ N+G DVLYQPP S+T++ LQSG KM FP+ KVE C+V VT G
Sbjct 3243 EAACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVFPTSKVEPCVVSVTYG 3302
Query 3264 TTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQ 3323
TLNGLWLDD VYCPRHVIC++ DM +P+Y +LL R + F V +G + L V+ + MQ
Sbjct 3303 NMTLNGLWLDDKVYCPRHVICSSADMTDPDYSNLLCRVISSDFCVMSGRMSLTVMSYQMQ 3362
Query 3324 NCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNG 3383
LL L V NP TPKY F ++PG+TF+VLA YNG G + MR ++TIKGSFL G
Sbjct 3363 GSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGKSQGAFHVTMRSSYTIKGSFLCG 3422
Query 3384 SCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLN 3443
SCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q Q D T T+N
Sbjct 3423 SCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVN 3482
Query 3444 VLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLD 3503
V+AWLYAA++N WF+ + +L +FN+ AM + + D V L L++ TG+ V
Sbjct 3483 VVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQ 3540
Query 3504 MCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLT 3563
+ AA+K L +G G+ ILGS +LEDE TP DV +Q +GV Q K ++VKGT W+L +
Sbjct 3541 ILAAIKRLY-SGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVVKGTCCWILAS 3599
Query 3564 FLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLAT 3623
L I+ +W++F +V + L TL + + AMLLVKHKH +L +F++P L T
Sbjct 3600 TLLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLVKHKHLYLTMFIMPVLCT 3658
Query 3624 VAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVL-LILMTARTVYDDA 3681
+ Y N +V S+ WL ++ Y D V+Y L++ ++ +T R++ D
Sbjct 3659 LFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLYGVVLLVAMVFVTMRSINHDV 3717
Query 3682 ARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVE 3741
++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA A V
Sbjct 3718 FSVMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWL 3773
Query 3742 YYPLLFITG-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYM 3800
+L+ T ++ ++L Y +GY CCCY+G+ LLN FR+ LGVY+Y +S QE RYM
Sbjct 3774 AVNVLYFTDVPQVKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYM 3833
Query 3801 NSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVES 3860
N+ GL PP++S +A LN KLLGIGG P I+V+ +QS+++DVKC +VVLL+ LQ L + S
Sbjct 3834 NANGLRPPRNSFEALVLNFKLLGIGGVPVIEVSQIQSRLTDVKCVNVVLLNCLQHLHIAS 3893
Query 3861 SSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLCEEMLDN 3914
SSKLW C LHN+IL D + AF+K+ LL VL + AVD I + ++ + +
Sbjct 3894 SSKLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRD 3953
Query 3915 RATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAA 3973
LQA+ SEF ++ S+ Y A++ ++A A+G + + +K+L+K+ N+AKS ++RD A
Sbjct 3954 STVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRA 4013
Query 3974 MQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGC 4033
+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GC
Sbjct 4014 VARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKLDNQALNSILDNAVKGC 4073
Query 4034 VPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINM 4093
VPLN IP T+ L ++VPD + D TYA +W IQ + DAD + QL+EI++
Sbjct 4074 VPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDV 4133
Query 4094 DNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNN 4151
N+ WPL++ A R N S+V LQNNEL P LR +G+ T YYN
Sbjct 4134 ----NITWPLVIAANRHNEVSSVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ--CYYNT 4187
Query 4152 SKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGL 4211
+ G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG
Sbjct 4188 TGMGKIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGC 4246
Query 4212 NNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNC 4271
N L RG V+G+L++TVRLQAG ATE +NS + S CAF+VDP K Y DY+ GG P+TNC
Sbjct 4247 NTLARGWVVGTLSSTVRLQAGTATEYASNSAIRSLCAFSVDPKKTYLDYIQQGGAPVTNC 4306
Query 4272 VKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPT 4331
VKMLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4307 VKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPL 4366
Query 4332 TCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSA-ARLTP 4390
DPV + L + VC VCG W+ CSC + + FLNRV G S ARL P
Sbjct 4367 G-IKDPVSYVLTHDVCQVCGFWRDGSCSCVGTGSQF--QSKDTNFLNRVRGTSVNARLVP 4423
Query 4391 CGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQ 4450
C +G TDV RAFDI N AG + K NCCRFQ DE+GN LD +FV+KR + Y
Sbjct 4424 CASGLDTDVQLRAFDICNANRAGIGLYYKVNCCRFQRADEDGNTLDKFFVIKRTNLEVYN 4483
Query 4451 HEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDT 4510
E+ Y L K+C VA H+FF F V+G VPHI R+ L+KYTM DL YALRHFD +C T
Sbjct 4484 KEKECYELTKECGVVAEHEFFTFDVEGSRVPHIVRKDLSKYTMLDLCYALRHFDRNDCST 4543
Query 4511 LKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGI 4570
LKEIL+TY CD+ YF KKDWYDFVEN DI+ VY LG ++LL T +F D + +AG+
Sbjct 4544 LKEILLTYAECDESYFQKKDWYDFVENSDIINVYKKLGPIFNRALLNTAKFADTLVEAGL 4603
Query 4571 VGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADL 4630
VGVLTLDNQDL G WYDFGDFV+ PGCGV + DSYYS +MP+LT+ AL +E ++
Sbjct 4604 VGVLTLDNQDLYGQWYDFGDFVKTVPGCGVAVADSYYSYMMPMLTMCHALDSELFINGT- 4662
Query 4631 AKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVF 4690
++DL++YDFT+ +L LF++YFKYW TYHPN C DDRCI+HCANFN+LFS V
Sbjct 4663 ---YREFDLVQYDFTDFKLELFNKYFKYWSMTYHPNTCECEDDRCIIHCANFNILFSMVL 4719
Query 4691 PPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMH 4750
P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YAADPA+H
Sbjct 4720 PKTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYAADPALH 4779
Query 4751 AASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFF 4810
AS + LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV+LKHFF
Sbjct 4780 VASASALLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSVDLKHFF 4839
Query 4811 FAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKS 4870
F QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV+KYF+ YDGGCI A QVIVNN DKS
Sbjct 4840 FTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVNKYFEIYDGGCIPATQVIVNNYDKS 4899
Query 4871 AGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVS 4930
AG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVS
Sbjct 4900 AGYPFNKFGKARLYYEALSFEEQDEVYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVS 4959
Query 4931 ICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPK 4990
I STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPK
Sbjct 4960 ILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPK 5019
Query 4991 CDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTS 5050
CDRAMPN+LRI++SLVLARKH++CC+ + RFYRLANECAQVLSE+VMCGG YVKPGGTS
Sbjct 5020 CDRAMPNILRIISSLVLARKHDSCCSHTDRFYRLANECAQVLSEIVMCGGCYYVKPGGTS 5079
Query 5051 SGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEF 5110
SGDATTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD F
Sbjct 5080 SGDATTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAF 5139
Query 5111 VDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWT 5170
V+E+Y +L KHFSMMILSDD VVCYNS +A++G +A+I F+ VLYYQNNVFMSEAKCW
Sbjct 5140 VNEYYEFLNKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQVLYYQNNVFMSEAKCWV 5199
Query 5171 ETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVS 5230
ETD+ KGPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVS
Sbjct 5200 ETDIEKGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVS 5259
Query 5231 LAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFY 5290
LAIDAYPL H N EY +VF +YL+YI+KL+++L +LD YSV+L+ + ++ + FY
Sbjct 5260 LAIDAYPLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSYSVILSTCDGQKFTDETFY 5319
Query 5291 EAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYV 5350
+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VLSV+PYV
Sbjct 5320 KNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPYV 5379
Query 5351 CNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAI 5410
CN+PGCDV DVT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS + DFN I
Sbjct 5380 CNSPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNKI 5439
Query 5411 ATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEV 5470
A+C WT DY+LAN CTERLKLFAAET KATEE+FK Y AT+RE++SDREL LSWE+
Sbjct 5440 ASCKWTEVDDYVLANECTERLKLFAAETQKATEESFKQCYASATIREIVSDRELILSWEI 5499
Query 5471 GKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTS 5530
GK RPPLN+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD F+LTS
Sbjct 5500 GKVRPPLNKNYVFTGYHFTSNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFILTS 5559
Query 5531 HTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS 5590
H V LSAPTLVPQE+Y I ++ + F +NV NYQ +GM++Y T+QGPPGTGKS
Sbjct 5560 HAVSSLSAPTLVPQENYTSI-RFASVYSVPETFQNNVPNYQHIGMKRYCTVQGPPGTGKS 5618
Query 5591 HFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVN 5650
H AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+C+DKFKVN
Sbjct 5619 HLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNINDCTRIVPAKVRVDCYDKFKVN 5678
Query 5651 STLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPR 5710
T +YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGDPAQLPAPR
Sbjct 5679 DTTRKYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGDPAQLPAPR 5738
Query 5711 TLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSA 5770
LL KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY NKLKA D S+
Sbjct 5739 VLLNKGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYHNKLKAKNDNSS 5798
Query 5771 QCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLP 5830
CFK++YKG TH+ SSA+N QI ++ +FL NP+W AVFISPYNSQN VA ++LGL
Sbjct 5799 MCFKVYYKGQTTHESSSAVNMQQIYLISKFLKANPSWSNAVFISPYNSQNYVAKRVLGLQ 5858
Query 5831 TQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTS 5890
TQTVDS+QGSEYD+VI++QT ETAHS NVNRFNVAITRAK GILC+MS L++ L F++
Sbjct 5859 TQTVDSAQGSEYDFVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSSMQLFESLNFST 5918
Query 5891 LEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEG-LCVDIPGIPK 5949
L + + N LQ T LFKDCS+ G HP AP+ L+VD K+K G L V +
Sbjct 5919 LTLDKINNPRLQ--CTTNLFKDCSRSYAGYHPAHAPSFLAVDDKYKVGGDLAVCLNVADS 5976
Query 5950 DMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPL 6009
+TY RLIS+MGFK++ ++GY +FITR+EAIR VRAW+GFD EG HATRD++GTN PL
Sbjct 5977 AVTYSRLISLMGFKLDLTLDGYCKLFITRDEAIRRVRAWVGFDAEGAHATRDSIGTNFPL 6036
Query 6010 QLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIV 6069
QLGFSTG++ V TG + F + A+ PPG+QFKHL+PLM +G W+VVRI+IV
Sbjct 6037 QLGFSTGIDFVVEATGMFAERDGYVFKKAVARAPPGEQFKHLVPLMSRGQKWDVVRIRIV 6096
Query 6070 QMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACW 6129
QMLSD L L+D VV V WA FELT ++YF K+G E C +C+KRATCF++ + Y CW
Sbjct 6097 QMLSDHLVDLADSVVLVTWAASFELTCLRYFAKVGKEVVCSVCNKRATCFNSRTGYYGCW 6156
Query 6130 NHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFV 6189
HS DY+YNP ++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF
Sbjct 6157 RHSYSCDYLYNPLIVDIQQWGYTGSLTSNHDLICSVHKGAHVASSDAIMTRCLAVHDCFC 6216
Query 6190 KRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVE 6249
K V+WS+EYPII +E+ VN++CR +Q ++ ++A+L +++ V +DIGNPK + CV +
Sbjct 6217 KSVNWSLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKG--YD 6274
Query 6250 WKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLS 6309
+KFYDA P +++ Y Y H D+F DG+C+FWNCNVD+YPANA+VCRFDTRVL+
Sbjct 6275 FKFYDASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLN 6331
Query 6310 NLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVP 6369
LNLPGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVP
Sbjct 6332 KLNLPGCNGGSLYVNKHAFHTSPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVP 6391
Query 6370 LKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQ 6429
L+SATCITRCNLGGAVC HA +YR+YL++YN +AGF+ W+YK FD YNLWNTFTRLQ
Sbjct 6392 LRSATCITRCNLGGAVCLKHAEDYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQ 6451
Query 6430 SLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAK 6489
SLENV YN+VN GHFDG AGE P ++I V K+ DV +F+N T P NVA EL+AK
Sbjct 6452 SLENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAK 6511
Query 6490 RNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLT 6549
R+I+P PE+K+ NL +D+ + V+WDY +++ ST VC TD+ SL
Sbjct 6512 RSIRPHPELKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYTDL------QCIESLN 6565
Query 6550 VLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLI---GESVKTQFN 6606
VLFDGR G ++ F+ R+GV I +K L+ KGP +A +NGV + V+ F
Sbjct 6566 VLFDGRDNGALEAFKKCRDGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFA 6625
Query 6607 YFKKVDGIIQQLP-------------------------------ETYFTQSRDLEDFKPR 6635
+ D +I T FTQSR L F PR
Sbjct 6626 MRRDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRFLSSFAPR 6685
Query 6636 SQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLE 6695
S+ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHL+IGLA+R Q S L ++
Sbjct 6686 SEMEKDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRQQKSNLVIQ 6745
Query 6696 DFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAE 6755
+F+P DS++ +YFITD +GSSK VC+VIDLLLDDFV+I+KS +L+ +SKVV V +D+ +
Sbjct 6746 EFVPYDSSIHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKSLNLNCVSKVVNVNVDFKD 6805
Query 6756 ISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGI 6815
FMLWC + V TFYP+LQA+ W+PG MP LYK LE+ +L NYG+ +P G
Sbjct 6806 FQFMLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPLERVNLWNYGKPITLPTGC 6865
Query 6816 MMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDL 6875
+MNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+AVLRQWLP G++LVD+D+
Sbjct 6866 LMNVAKYTQLCQYLNTTTLAVPANMRVLHLGAGSDKDVAPGSAVLRQWLPAGSILVDNDI 6925
Query 6876 NDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQK 6935
N FVSD+ ++ G+C T+ A +WDLIISDMYDP TK++ + N SK+GFFTYLC I+ K
Sbjct 6926 NPFVSDSVASYYGNCITLPIACQWDLIISDMYDPLTKNIGEYNVSKDGFFTYLCHLIRDK 6985
Query 6936 LALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQID 6995
LALGGS+A+KITE SWNA+LY LMG F++WT F TNVNASSSE FLIG N+L + + +ID
Sbjct 6986 LALGGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNRTRTEID 7045
Query 6996 GYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRL 7055
G TMHANY+FWRN+ +YSLFDMSKFPLK+ GTAV+SLK +QIND++ SL+EKG+L
Sbjct 7046 GKTMHANYLFWRNSTMWNGGAYSLFDMSKFPLKVAGTAVVSLKPDQINDLVLSLIEKGKL 7105
Query 7056 IIRENNRVVVSSDILVN 7072
++R+ + V D LVN
Sbjct 7106 LVRDTRKEVFVGDSLVN 7122
Score = 347 bits (891), Expect = 2e-93, Method: Composition-based stats.
Identities = 205/998 (21%), Positives = 341/998 (34%), Gaps = 165/998 (17%)
Query 93 DGIQYGRSGITLGVLVPHVGETPIAYR-----NVLLRKNGNKGA---GGHSYGIDLKSYD 144
DG+ G +G +G VP A + ++LLRK GNKG+ G + + YD
Sbjct 158 DGVCLG-NGRFIGWFVPVTAIPAYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYD 216
Query 145 LGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPLDCIKDF 204
E D E+ N K+ A L + G ++D C G ++D+
Sbjct 217 FNVE---DACEEVHLNPKGKYSRKAYA-LLKGYRGVKSILFLDQYGCDYTGRLAKGLEDY 272
Query 205 LARAGKSMCTLSEQLDYIESKRGVYCCR-DHEHEIAWFTERSDKSYEH-QTPFEIKSAKK 262
CTL E + V+C D+E +AW +R ++ QT I+S
Sbjct 273 ------GDCTLEEMKELFP----VWCDSLDNEVVVAWHVDRDPRAVMRLQTLATIRSIGY 322
Query 263 FDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQE--CNNMHLSTL 320
+ ++ V V +P R V + + + L
Sbjct 323 VGQPTEDL------VDGDVVVREPAHLLAANAIVKRLPRLVETMLYTDSSVTEFCYKTKL 376
Query 321 MKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYLPTNAVVKMPCPACQDP---- 376
C + + C CG + G++P N + CP C
Sbjct 377 CDCGFITQFGYVDC---------CG------DACDFRGWVPGNMMDGFLCPGCSKSYMPW 421
Query 377 --EIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADIGSG 434
E + T + +G V VP SA S
Sbjct 422 ELEAQSSGVIPKGGVLFTQSTDTVNRESFKLYGHAV-------------VPFGSAVYWSP 468
Query 435 HTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSL 494
+ G+ L ++ D V A + ++
Sbjct 469 YPGMW--------------LPVIWSSVKSYADLTYTGVVGC---------KAIVQETDAI 505
Query 495 DYKSFKTIVES-CGNYKVTKGKPVKGA------WNIGQQRSVLTPLCGFPSQAAGVIRSI 547
+ V+ CGN + + N G +L + F + A
Sbjct 506 CRSLYMDYVQHKCGNLEQRAILGLDDVYHRQLLVNRGDYSLLLENVDLFVKRRAEFACKF 565
Query 548 FARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDA-------MVYTSDLLTNSVIIMAY 600
+ D +LDG+ +S L+ + MV S +T+ + MA
Sbjct 566 A---------TCGD--GLVPLLLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMAL 614
Query 601 VTGGLVQQTSQWLSNLLGTT--------VEKLRPIFEWIEAKLSAGVEFLKDAWEILKFL 652
+ V+ ++++ + G V +R I EW + + W + L
Sbjct 615 LFMHDVKVATKYVKKVTGKLAVRFKALGVAVVRKITEWFDLAVDTAAS--AAGWLCYQ-L 671
Query 653 ITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIA---GAKLRSLNLGEVF 709
+ G+F + G I SD + + VK F+D ++ ID ++++ G + V
Sbjct 672 VNGLFAVANGGITFLSD-VPELVKNFVDKFKVFFKVLIDSMSVSVLSGLTVVKTASNRVC 730
Query 710 IAQSKGLYRQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGEL--EALE 767
+A K + K +MP+ E T L G+ V+ + V + L +
Sbjct 731 LAGCKVY---EVVQKRLSAYVMPVGCN-EATCLVGEIEPAVVEDDVVDVVKAPLTYQGCC 786
Query 768 TPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSP---GLLATNNVFRLKGGAPIKGV 824
P SF +V + L + + D+ + G+L F G K V
Sbjct 787 KPPTSFEKICVV------DKLYMAKCGDQFYPVVVDNDTIGVLDQCWRFPCAG----KKV 836
Query 825 TFGED-TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKT 883
F + V E+ + ++I F LD D VL++ CS + V+ + E VV +AV T
Sbjct 837 EFNDKPKVKEIPSTRKIKINFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVEST 896
Query 884 LQPVSD---LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEE 940
L P + + T + L+ + YLFD+ GEE + +MYCSF PD+E+ C
Sbjct 897 LSPCKEHDVIGTKVCALLNRLAEDYVYLFDEGGEEVIAPKMYCSFSAPDDED-----CVA 951
Query 941 EEIDETCEHEYGTEDDYQGLPL----EFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPE 996
++ + E++ DD L E G + V V E + D E +IE +
Sbjct 952 ADVVDADENQGDDADDSAALVTDTQEEDGVAKGQVGVAESDAR---LDQVEAFDIEKVED 1008
Query 997 PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMV 1034
P E + T + I EA SA V
Sbjct 1009 PILNELSAELNAPADKTYEDVLAFDAIYSEALSAFYAV 1046
Score = 137 bits (346), Expect = 4e-30, Method: Composition-based stats.
Identities = 52/156 (33%), Positives = 78/156 (50%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV D++K + VIVN AN + HG GVAGA+ KA + KE+ D +K
Sbjct 1266 CITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKSFIKETADMVK 1325
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAG--EDIQLLKAAYENFNSQDILLAPLLS 1128
G VG +G NL K L++VGP+ + L+ AY++ N D ++ L+S
Sbjct 1326 NQGVCQVGECYESTGGNLCKTVLNIVGPDARGHGKQCYSFLERAYQHINKCDDVVTTLIS 1385
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + V V + N+K ++ +
Sbjct 1386 AGIFSVPTDVSLTYLIGVVTKNVILVSNNKDDFDVI 1421
Score = 43.1 bits (100), Expect = 0.16, Method: Composition-based stats.
Identities = 46/239 (19%), Positives = 82/239 (34%), Gaps = 28/239 (12%)
Query 1551 VDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDT-LRSEAF 1609
D V S Q + D+ K++ + +E P+D T AF
Sbjct 978 EDGVAKGQVGVAESDARLDQV-----EAFDIEKVEDPILNELSAELNAPADKTYEDVLAF 1032
Query 1610 EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNA 1669
+ + L + + +K G S NC+L S L+ +Q L ++F
Sbjct 1033 DAIY---SEALSAFYAVPGDETHFKVC---GFYSPAIERTNCWLRSTLIVMQSLPLEFKD 1086
Query 1670 PALQEAYYRARAGDAANFCALILAYSNKTVGEL--GDVRETMTHLLQHANLESAKRVLNV 1727
+Q+ + ++ F ++ K++ G V + L S K N
Sbjct 1087 LEMQKLWLSYKSSYNKEFVDKLVKSVPKSIILPQGGYVADFAYFFLSQ---CSFKAYANW 1143
Query 1728 VCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSA 1786
C C L G++A+ + G + VS C CG T L+ + + +
Sbjct 1144 RCLKCDM-DLKLQGLDAMFFYGDV--------VSHVCKCGTGMT--LLSADIPYTLHFG 1191
>sp|P0C6X0|R1AB_CVBQ Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=rep PE=3 SV=1
Length=7059
Score = 7839 bits (20341), Expect = 0.0, Method: Composition-based stats.
Identities = 2939/7109 (41%), Positives = 4045/7109 (57%), Gaps = 463/7109 (7%)
Query 107 LVPHVGETPIAYRNVLLRKNGNKGA-------GGHSYGIDLKSYDLGDELGTDPIEDYEQ 159
+P IA + LRK G KGA GG + + K D D + +P + +
Sbjct 176 FMPVQSRKFIAPWVMYLRKCGEKGAYIKDYKRGGFEHVYNFKVEDAYDLVHDEPKGKFSK 235
Query 160 NWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYP---LDCIKDFLARAGKSMCTLS 216
L R G YVD C G L+ D + K++ +
Sbjct 236 KAYA---------LIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIW 286
Query 217 EQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSAK-----KFDTFKGEC 270
Q + +AW R + Q+ I+S D G
Sbjct 287 SQELPFD------------VTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSV 334
Query 271 ----PKFVFPLNSKVKVIQPRVEKKKTEGFMGR--IRSVYPVASPQECNNMHLSTLMKC- 323
P V+ +S + V+ + + Y V ++C + + C
Sbjct 335 VIKEPVHVYADDSIILRQHNLVDIMSCFYMEADAVVNAFYGVD-LKDCGFVMQFGYIDCE 393
Query 324 -NHCDEVSWQTCDFLKATCEH-CGTENLVIEGP-TTCGYLPTNAVVKMPCPACQDPEIGP 380
+ CD W + + CG + + G LP N V+
Sbjct 394 QDLCDFKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHT------------ 441
Query 381 EHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADI----GSGHT 436
S A Y ++ G FGGCV+ R W+P + + G +T
Sbjct 442 -KSAAGYGGFGCKDSFTLYGQTVVYFGGCVY----WSPARNIWIPILKSSVKSYDGLVYT 496
Query 437 GITGDNVETLNEDLL---EILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKS 493
G+ G +L+ L + + L + + + +++
Sbjct 497 GVVGCKAIVKETNLICKALYLDYVQHKCGNLHQRELLGVSDVWHKQLLLNRGVYKPLLEN 556
Query 494 LDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLD 553
+DY + + S + V + + R+ + G QA D
Sbjct 557 IDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSG---QAFC----------D 603
Query 554 AANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQWL 613
A + + +LD VD++ L + ++ +A Q
Sbjct 604 YAGKICHAVVSKSKELLD-------VSVDSLGAAIHYLNSKIVDLA-----------QHF 645
Query 614 SNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
S+ + V K+ F+ L AW + L G + +V+ I NI
Sbjct 646 SDFGTSFVSKIVHFFKTF-----TTSTALAFAWVLFHVL-HGAYIVVESDIYF-GKNIPR 698
Query 674 CVKCFIDVVNKALEMCIDQVT---IAGAKLRSLNLGEVFIAQSK------GLYRQCIRGK 724
++ +D + I G + + ++ SK GL
Sbjct 699 YASAVAQAFRSGAKVGLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERGLLHSSQLPL 758
Query 725 EQLQLLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGT 781
+ L MP K ++ +L+G D L V + L ++ V
Sbjct 759 DVYDLTMPSQVQKTKQKGIYLKGSGSDFSLADSVVEVVTTSLTPC-----GYSEPPKVAD 813
Query 782 PVCV-NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-K 838
+C+ + + + + DK + + + +R+ + VTF E TV E+ K
Sbjct 814 KICIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAG--RCVTFKEQPTVNEIASTPK 871
Query 839 NVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDL---LTNMG 895
+++ +ELD+ + +LN C + V+ ++ EF VV +A+ + L P +L +
Sbjct 872 TIKVFYELDKDFNTILNTACGEFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVS 931
Query 896 IDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDD--------------AECEEE 941
L + + +LFD+AGEE + ++YC+F P++++ +
Sbjct 932 AFLQKLEDNSLFLFDEAGEEVLAPKLYCAFTAPEDDDFLEESGVEEDDVEGEETDLTVTS 991
Query 942 EIDETCEHEYGTEDDYQGLPLEFG--ASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTP 999
+ E + L+ G +VEE+ + D +
Sbjct 992 AGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVQMSDFGDLESVIQDYENVCFEF 1051
Query 1000 EEPVNQFTGYLKLTDNVAIKCVDIVKEAQSA---------------------------NP 1032
+F L L A + ++ +
Sbjct 1052 YTTEPEFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFV 1111
Query 1033 MVIVN--AANIHLKHGGGVAGALNKATNGAMQKESD-DYIKLNGPLTVGGSCLLSGHNLA 1089
+VN ANI + GG VA D + + + L G +
Sbjct 1112 DTLVNKIPANIVVPQGGYVAD-----FAYWFLTLCDWQCVAYWKCIKCDLALKLKGLDAM 1166
Query 1090 KKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
VV GE + L+ + + L L + + V +
Sbjct 1167 FFYGDVVSHVCKCGESMVLID--VDVPFTAHFALKDKLFCAFITKRSVYKAACVVDVNDS 1224
Query 1150 QVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEE-----KSVVQKPVDV 1204
V+ K + + + + + T + +V D+
Sbjct 1225 HSMAVVDGKQIDDHRITSITSDKFDFIIGHGTSFSMTTFEIAQLYGSCITPNVCFVKGDI 1284
Query 1205 KPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVG 1264
K EV + + + + E ++ G
Sbjct 1285 IKVSKRVKAEVVVNPANGH-----MAHGGGVAKAIAVAAGQQFVKETTDMVKSKGVCATG 1339
Query 1265 DVITSGD------ITCVVIPSKKA--GGTTEMLSRALKKVPVDEYITT---------YPG 1307
D S + VV P + + +L R K + + + T P
Sbjct 1340 DCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISAGIFSVPS 1399
Query 1308 QGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPI 1367
Y L AK + + + + GT R I
Sbjct 1400 DVSLTYLLGTAKKQVVLVSNNQEDFDLISKCQITAVEGTKKLAERLSFNVGRS------I 1453
Query 1368 CMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIG 1427
+ A + F ++ + +++
Sbjct 1454 VYETDANKLILSNDVA----------------FVSTFNVLQDVLS--------------- 1482
Query 1428 YVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSY 1487
+ H L++ AR V P+ N + + ++F
Sbjct 1483 -LRHDIALDDDARTFVQSNVDVV-----PEGWRVVNKFYQINGVRPVKYF---------- 1526
Query 1488 RDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKV 1547
G++ + Y S + ++ ++K+L + + +
Sbjct 1527 --------ECPGGIDICSQDKVFGYVQQGSFNK-------ATVAQIKALF----LDKVDI 1567
Query 1548 FTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSE 1607
TVD N + V + ++G+ G + DG +VTK K +N++GK FF + + +
Sbjct 1568 LLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLK 1627
Query 1608 AFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKF 1667
A D+ L Y + L + KW+ G + K A+NNC+++ L LQ L +KF
Sbjct 1628 AVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLNLKF 1687
Query 1668 NAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNV 1727
QEA+ R+G A F +L+LA G+ D R+ + + +L A +
Sbjct 1688 KIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEI 1747
Query 1728 VCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAP 1787
CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG+ + V+ + F++ S
Sbjct 1748 ACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLICSNT 1805
Query 1788 PAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFY-K 1846
PA KL +G AN + G+ + GHY H+ +++ D +++ K+++ G ++D Y K
Sbjct 1806 PASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCLYLK 1863
Query 1847 ETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLPNASFDNF 1905
T +Y LD V E +P L YY YYT++ I T + + NF
Sbjct 1864 NLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNF 1923
Query 1906 KLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLH 1964
KL D LN GF + E VT +P GDVV Y +++G
Sbjct 1924 KLI--GHTVCDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGCITFG 1981
Query 1965 KPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFEVLAVEDTQGMDNLACESQQP 2023
KP++W ++ + + + +P+ N F+VL V+D +++ +
Sbjct 1982 KPVIWLSHEQASLNSLT---------YFNRPLLVDENKFDVLKVDDVDDGGDISESDAK- 2031
Query 2024 TSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSIT 2083
E E I+ ++ K +V +VI+ +K + L D+ ++
Sbjct 2032 ---EPKEINIIKLSGVK---KPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLTGCRCV 2085
Query 2084 IKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRV-- 2141
++ N LS A+ + TI + V L + N K + ++
Sbjct 2086 VRTANALSRAVNVPTIRKFIKFGMTLVSIPIDL-----LNLREIKPVFNVVKAVRNKISA 2140
Query 2142 FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFS 2201
N++ ++F LLF + + T +A K KL A N + K+S
Sbjct 2141 CFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---KLTCKLVALAFKNAFLTFKWS 2193
Query 2202 KLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSYCNGVRELYLNSSNVTT---- 2255
+ A + + + + I F L G P++ + + N+ ++ T
Sbjct 2194 VVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIVQWIKNTFSLVTICDL 2253
Query 2256 ---------MDFCEGSFPCSICLSGLDSLDSYPALETIQVTISS--YKLDLTILGLAAEW 2304
+C GS C CL+G D LD+Y A++ +Q + +L + E
Sbjct 2254 YSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIEL 2313
Query 2305 VLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYI 2362
+++Y L+T +FY L +Q+ + + ++ W + ++S+ M P +R YI
Sbjct 2314 IVSYALYTAWFYPLFALISIQILTTWLPELLMLSTLHWSVRLLVSLANMLPAHVFMRFYI 2373
Query 2363 FFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFC 2422
ASF ++ + H+ GC+ S C+ CYKRNR+ RV+C+TIV GM R + V ANGG GFC
Sbjct 2374 IIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFC 2433
Query 2423 KTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYF 2482
H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V V + L++
Sbjct 2434 SKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFY 2493
Query 2483 DKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLM 2542
D+ GQ+TY+ S FV+ NL + K ++V+V + + D++ +A+V+Y+Q +
Sbjct 2494 DRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DKANFLNAAVFYAQSL 2551
Query 2543 CQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVA 2602
+PIL++D+ L++ T V+ MFD YVDTF + F V + L AL+ATAHS + +G
Sbjct 2552 FRPILMVDKILITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQ 2611
Query 2603 LDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMT 2661
+ VL TF+S AR+ +D+DVDTK + + + + + LE+T +SCNN + TY K +N+
Sbjct 2612 ICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDNIV 2671
Query 2662 PRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTC 2721
DLG I +A+H+ VAK VS IW+V + LS + +++ A K + LT
Sbjct 2672 AADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLELTY 2731
Query 2722 ATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTN 2781
V+V+TT SLKGG + S + +L+C + + +MP +T+ D
Sbjct 2732 NKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLVCFI---GLWCLMPTYTVHKSDFQLP 2788
Query 2782 EIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREI 2839
YK + +GV RD+ D CFANK FD W+ G Y N +CP+V A++ ++
Sbjct 2789 VYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVVDQDF 2848
Query 2840 GFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIF 2899
G V +P VLR LHF+ SA G CYTP I YS+F S CVL++ CT+F
Sbjct 2849 GSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVLSSACTMF 2907
Query 2900 KDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SIIQFPNTYLEGSVRVVTTFDA 2958
A G P PYCY L++ + YS L P RY L + I+ P EG VR+V T
Sbjct 2908 AMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRLPEVLREGLVRIVRTRSM 2967
Query 2959 EYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGAL 3018
YCR G CE ++ GIC + +G WVLNN++YR+L G FCG D +LI +F L QPV L
Sbjct 2968 SYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLFKGLAQPVDFL 3027
Query 3019 DVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFL 3078
++AS +AG I+A++V YY +K +R FG+Y +V N +++ ++F +L + Y L
Sbjct 3028 ALTASSIAGAILAVIVVLGFYYLIKLKRAFGDYTSIVFVNVIVWCVNFMMLFVFQVYPTL 3087
Query 3079 PGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYL 3138
VY++ Y Y T YF +++S + HLQW M+ I+P W +Y+ + H W F+
Sbjct 3088 SCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYISVVVSNHAFWVFSYC- 3146
Query 3139 RKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGAL 3198
+++ + + TFEE AL TF++ K+ Y KL++ L +NRYL+LYNKY+Y+SG +
Sbjct 3147 -RQLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNRYLSLYNKYRYYSGKM 3203
Query 3199 DTTSYREAACCHLAKALNDF-SNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3257
DT +YREAAC LAKA++ F +N+G+DVLYQPP S++++ LQSG KM P+ KVE C+
Sbjct 3204 DTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSGIVKMVNPTSKVEPCI 3263
Query 3258 VQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRV 3317
V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +LL R ++ F V + L V
Sbjct 3264 VSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVTSSDFTVLFDRLSLTV 3323
Query 3318 IGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIK 3377
+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P G + MR ++TIK
Sbjct 3324 MSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIK 3383
Query 3378 GSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTD 3437
GSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G FYGP+ D Q Q D
Sbjct 3384 GSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPVQD 3443
Query 3438 TTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQT 3497
++N +AWLYAA++N WF+ ++ DFN+ A+ + + D V + L++ T
Sbjct 3444 YIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQVKSDLV--IDALASMT 3501
Query 3498 GIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTH 3557
G+++ + AA+K L +NG GR I+GS EDE TP DV +Q +G+ Q K ++VKG
Sbjct 3502 GVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQSKRTRLVKGIV 3560
Query 3558 HWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFL 3617
W++ + I+ +W++F +V N L T + + + AMLLVKHKH +L +++
Sbjct 3561 CWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLVKHKHLYLTMYI 3619
Query 3618 LPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVL-LILMTAR 3675
+P L T+ Y N +V ++ + WL S+ Y D V+Y L++ ++ +T R
Sbjct 3620 IPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGMLLLIGMVFVTLR 3678
Query 3676 TVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAI 3735
++ D + + VI++V Y G+ L++ I + ++ S+ Y+ M A+ I
Sbjct 3679 SINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTYTWTTALSMAAAKVI 3736
Query 3736 VFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQ 3795
V L F ++ +++ Y F+GY CY+GLF L+N FR+ LGVY+Y +S Q
Sbjct 3737 A-KWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQ 3795
Query 3796 EFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQ 3855
E RYMN+ GL PPK+S +A LN KLLGIGG P I+V+ QSK++DVKC + LL+ LQ
Sbjct 3796 ELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANGGLLNCLQH 3855
Query 3856 LRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLCE 3909
L V S+SKLW C LHN+IL D AFEK+ LL VL + AVD I +C+
Sbjct 3856 LHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPAAVDSKCLTSIEEVCD 3915
Query 3910 EMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEF 3968
+ + LQA+ SEF ++ S+ Y A++ ++A ++G + + LK+L+K+ N+AKS +
Sbjct 3916 DYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAY 3975
Query 3969 DRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINN 4028
+RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++N
Sbjct 3976 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDN 4035
Query 4029 ARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQL 4088
A GCVPLN IP A L ++VPD Y D TYA +W+IQ + D+D QL
Sbjct 4036 AVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQL 4095
Query 4089 SEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNAL 4146
EI S + WPL++ A R N SA LQNNEL P L+ +G QT T
Sbjct 4096 HEI----SDDCNWPLVIIANRHNEVSATVLQNNELMPAKLKTQVVNSGPDQTCNTPTQ-- 4149
Query 4147 AYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLY 4206
YYNNS G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLY
Sbjct 4150 CYYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCKFTVQDVKGLKIKYLY 4208
Query 4207 FIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQ 4266
F+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+VDP K Y D++ GG
Sbjct 4209 FVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSVDPKKTYLDFIQQGGT 4268
Query 4267 PITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKY 4326
PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR ++HP+ G C L+GK+
Sbjct 4269 PIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCRARVEHPDVDGLCKLRGKF 4328
Query 4327 VQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSA- 4385
VQ+P DPV + L + VC VCG W+ CSC + +QS D + FLNRV G S
Sbjct 4329 VQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSKD-TNFLNRVRGTSVD 4385
Query 4386 ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHT 4445
ARL PC +G STDV RAFDI N VAG LK NCCRFQ DE G+ LD +FVVKR
Sbjct 4386 ARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRFQRVDENGDKLDQFFVVKRTD 4445
Query 4446 MSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDE 4505
++ Y E Y VKDC VA HDFF F V+G VPHI R+ LTKYTM DL YALRHFD
Sbjct 4446 LTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVRKDLTKYTMLDLCYALRHFDR 4505
Query 4506 GNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAM 4565
+C L +IL Y C+ YF KKDWYDFVENPDI+ VY LG ++L+ +F D +
Sbjct 4506 NDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYKKLGPIFNRALVSATEFADKL 4565
Query 4566 RDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESH 4625
+ G+VG+LTLDNQDLNG WYDFGD+V APGCGV I DSYYS +MP+LT+ AL E +
Sbjct 4566 VEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADSYYSYMMPMLTMCHALDCELY 4625
Query 4626 MDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVL 4685
++ +DL++YDFT+ +L LF++YFK+W YHPN ++C DDRCI+HCANFN+L
Sbjct 4626 VN----NAYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHPNTVDCQDDRCIIHCANFNIL 4681
Query 4686 FSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAA 4745
FS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N DV+ H RLS K+LL+YAA
Sbjct 4682 FSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMNMDVDTHRYRLSLKDLLLYAA 4741
Query 4746 DPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVE 4805
DPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN+DFYDF +SKG KEGSSV+
Sbjct 4742 DPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYDFILSKGLLKEGSSVD 4801
Query 4806 LKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVN 4865
LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGGCI A QVIVN
Sbjct 4802 LKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGGCIPAAQVIVN 4861
Query 4866 NLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRART 4925
N DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRART
Sbjct 4862 NYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRART 4921
Query 4926 VAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMG 4985
VAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV+ P LMG
Sbjct 4922 VAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDNPVLMG 4981
Query 4986 WDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVK 5045
WDYPKCDRAMPN+LRI++SLVLARKH CC+ S RFYRLANECAQVLSE+VMCGG YVK
Sbjct 4982 WDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLANECAQVLSEIVMCGGCYYVK 5041
Query 5046 PGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRD 5105
PGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI D +R LQ RLY +YR+
Sbjct 5042 PGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIEDLSIRALQKRLYSHVYRSDM 5101
Query 5106 VDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSE 5165
VD FV E+Y +L KHFSMMILSDD VVCYNS+YA++G +A+I F+ VLYYQNNVFMSE
Sbjct 5102 VDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYIANISAFQQVLYYQNNVFMSE 5161
Query 5166 AKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMI 5225
+KCW E D+ GPHEFCSQHTMLVK D VYLPYP PSRILGAGCFVDD++KTD L+I
Sbjct 5162 SKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPVPSRILGAGCFVDDLLKTDSVLLI 5221
Query 5226 ERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYW 5285
ERFVSLAIDAYPL H N+EY VF +YL+YI+KL++EL +LD YSV+L+ + ++
Sbjct 5222 ERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNELGNQILDSYSVILSTCDGQKFT 5281
Query 5286 EPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLS 5345
+ FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV++T HK VLS
Sbjct 5282 DESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHVMATDHKYVLS 5341
Query 5346 VNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVT 5405
V+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS +
Sbjct 5342 VSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYID 5401
Query 5406 DFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELH 5465
DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE FK SY AT++E++S+REL
Sbjct 5402 DFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEAFKQSYASATIQEIVSERELI 5461
Query 5466 LSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDY 5525
LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K + + V YR TTTYKL+VGD
Sbjct 5462 LSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDV 5521
Query 5526 FVLTSHTVMPLSAPTLVPQEHYV--RITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQG 5583
FVLTSH+V LSAPTLVPQE+Y R +Y L + F +NV NYQ +GM++Y T+QG
Sbjct 5522 FVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETFQNNVVNYQHIGMKRYCTVQG 5578
Query 5584 PPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVEC 5643
PPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RVEC
Sbjct 5579 PPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAYKFLNINDCTRIVPAKVRVEC 5638
Query 5644 FDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDP 5703
+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NAR+RAKHYVYIGDP
Sbjct 5639 YDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNYELSVINARIRAKHYVYIGDP 5698
Query 5704 AQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK 5763
AQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLK
Sbjct 5699 AQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYENKLK 5758
Query 5764 AHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVA 5823
A + S+ CFK++YKGV TH+ SSA+N QI ++ +FL NP W KAVFISPYNSQN A
Sbjct 5759 AKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKANPLWHKAVFISPYNSQNFAA 5818
Query 5824 SKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLY 5883
++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK GILC+MS+ L+
Sbjct 5819 KRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSNMQLF 5878
Query 5884 DKLQFTSLEIPRRNVA-TLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFK-TEGLC 5941
+ LQFT+L + + A + + T LFKDCSK +G HP AP+ L+VD K+K T L
Sbjct 5879 EALQFTTLTVDKVPQAVETRVQCSTNLFKDCSKSYSGYHPAHAPSFLAVDDKYKATGDLA 5938
Query 5942 VDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRD 6001
V + +TY RLIS+MGFK++ ++GY +FIT+EEA++ VRAW+GFD EG HATRD
Sbjct 5939 VCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEAVKRVRAWVGFDAEGAHATRD 5998
Query 6002 AVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPW 6061
++GTN PLQLGFSTG++ V TG + F + AK PPG+QFKHLIPLM +G W
Sbjct 5999 SIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAKAPPGEQFKHLIPLMTRGQRW 6058
Query 6062 NVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFST 6121
+VVR +IVQM +D L LSD VV V WA FELT ++YF K+G E +C + KRAT +++
Sbjct 6059 DVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFAKVGREISCNVSTKRATAYNS 6118
Query 6122 SSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRC 6181
+ Y CW HSV DY+YNP ++D+QQWG+ G+L SNHD +C VH AHVAS DAIMTRC
Sbjct 6119 RTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDLYCSVHKGAHVASSDAIMTRC 6178
Query 6182 LAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIK 6241
LAV++CF ++W+VEYPII +EL +N++CR +Q +++K+A+L +++ + +DIGNPKAI
Sbjct 6179 LAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKAAMLCNRYTLCYDIGNPKAIA 6238
Query 6242 CVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVC 6301
CV + ++KFYDAQP ++ L Y + H D F DG+C+FWNCNVD+YP NA+VC
Sbjct 6239 CVK--DFDFKFYDAQPI---VKSVKTLLYFFEAHKDSFKDGLCMFWNCNVDKYPPNAVVC 6293
Query 6302 RFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQV 6361
RFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +LK +PFFYYSD+PC
Sbjct 6294 RFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHLKPMPFFYYSDTPCVYMDGMD 6353
Query 6362 VSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNL 6421
+DYVPLKSATCITRCNLGGAVC HA EYR+YL++YN +AGF+ W+YK FD YNL
Sbjct 6354 AKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNL 6413
Query 6422 WNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVN 6481
WNTFT+LQSLENV YN+V GH+ G AGE P +IIN+ V K+D DV IF N TT P N
Sbjct 6414 WNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVVAKIDKEDVVIFINNTTYPTN 6473
Query 6482 VAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPT 6541
VA EL+AKR+I+ PE+K+ NL +D+ VIWDY RE+ +T GVC TD+
Sbjct 6474 VAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARESIFCSNTYGVCMYTDL----- 6528
Query 6542 ESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTL--IGE 6599
L VLFDGR G ++ F+ + NGV I+ VK L+ +GP +A +NGV + +G+
Sbjct 6529 -KLIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLSMIRGPPRAELNGVVVDKVGD 6587
Query 6600 SVKTQFNYFKK--------------------------------VDGIIQQLPETYFTQSR 6627
+ + +K V G T FTQSR
Sbjct 6588 TDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNEPGNVGGNDALATSTIFTQSR 6647
Query 6628 DLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRS 6687
+ F R+ ME DF+ L D FIQ+Y LE YAFEHIVYG+F+ +GGLHL+IGL +R
Sbjct 6648 VISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYGNFNQKIIGGLHLLIGLYRRQ 6707
Query 6688 QDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVV 6747
Q S L +++F+ DS++ +YFITD ++G SK VC+VID+LLDDFV ++KS +L+ +SKVV
Sbjct 6708 QTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDILLDDFVALVKSLNLNCVSKVV 6767
Query 6748 KVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGE 6807
V +D+ + FMLWC D V TFYP+LQA+ W+PG +MP LYK +E+ L NYG+
Sbjct 6768 NVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMPVLYKYLNSPMERVSLWNYGK 6827
Query 6808 NAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAV-------- 6859
+P G MMNVAKYTQLCQYLNT TLAVP N RV+H GAGS+KGVAPG+AV
Sbjct 6828 PVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNTRVLHLGAGSEKGVAPGSAVLRQWLPAG 6887
Query 6860 --LRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKE 6917
LRQWLP GT+LV +DL FVSD+ +T GDC T+ +WDLIISDMYD
Sbjct 6888 TILRQWLPAGTILVHNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMYDLLLDIGVHV 6947
Query 6918 NDSKEGFFTYL-CGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASS 6976
+Y+ C I+ KLALGGS+A+KITE SWNA+LYKLMG+F++WT F TN NASS
Sbjct 6948 VRC-----SYIHCHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTVFCTNANASS 7002
Query 6977 SEAFLIGANYLGKPKEQIDGYTMHANYIF 7005
SE FLIG NYLGKPK +IDG MHA F
Sbjct 7003 SEGFLIGINYLGKPKVEIDGNVMHAIICF 7031
>sp|P0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab OS=Murine coronavirus
(strain A59) OX=11142 GN=rep PE=1 SV=1
Length=7176
Score = 7832 bits (20322), Expect = 0.0, Method: Composition-based stats.
Identities = 2763/5649 (49%), Positives = 3666/5649 (65%), Gaps = 172/5649 (3%)
Query 1526 EVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIK 1585
+ S+ ++++LL + V TVD N + V +G+ G + DG +VTK++
Sbjct 1596 KEASVSQIRALL----ANKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR 1651
Query 1586 PHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIK 1645
++GK FF A + DE L +Y + L KW G + K
Sbjct 1652 CSAIYKGKVFFQYSDLSEADLVAVKDAFGFDEPQLLKYYTMLGMC-KWPVVVCGNYFAFK 1710
Query 1646 WADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDV 1705
++NNCY++ L LQ L +KF QEA+ R+G F +L+LA + E D
Sbjct 1711 QSNNNCYINVACLMLQHLSLKFPKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDS 1770
Query 1706 RETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCV 1765
+ M +L+ A+L A L VCK CG K GV+AVM+ GTL +L G +I C
Sbjct 1771 IDFMRVVLREADLSGATCNLEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLVRGYNIACT 1829
Query 1766 CGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRI 1825
CG + Q F++ S P KL + AN +TG GHYTH+ K
Sbjct 1830 CGSKLV-HCTQFNVPFLICSNTPEGRKLPDDV-VAANIFTGG-SVGHYTHVKCKPKYQLY 1886
Query 1826 DGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYY 1884
D ++ K+SE KG TD Y K T + ++ LD V E +P L YY + YY
Sbjct 1887 DACNVNKVSEAKGNFTDCLYLKNLKQTFSSVLTTFYLDDVKCVEYKPDLSQYYCESGKYY 1946
Query 1885 TEQPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNG 1942
T+ I T + + NFKL A+ LN GF E +T +P G
Sbjct 1947 TKPIIKAQFRTFEKVDGVYTNFKLV--GHSIAEKLNAKLGFDCNSPFVEYKITEWPTATG 2004
Query 1943 DVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF----KPNTWCLRCLWSTKPVDT 1998
DVV Y + + G KP+VW ++ + + +P+ C ++ PVD
Sbjct 2005 DVVLASDDLYVSRYSSGCITFGKPVVWLGHEEASLKSLTYFNRPSVVCEN-KFNVLPVDV 2063
Query 1999 SNSFE------VLAVEDTQGMD----------NLACESQQ---PTSEEVVENPTI----Q 2035
S + + V G D AC S EV + P++
Sbjct 2064 SEPTDKGPVPAAVLVTGVPGADASAGAGIAKEQKACASASVEDQVVTEVRQEPSVSAADV 2123
Query 2036 KEVIECDVKTT-EVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLAL 2094
KEV VK +V G+V++ KV + L D+ ++ + NELS +
Sbjct 2124 KEVKLNGVKKPVKVEGSVVVNDPTSETKVVKSLSIVDVYDMFLTGCKYVVWTANELSRLV 2183
Query 2095 GLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLF 2154
T+ + + KI+ K L + K + + Y + LL+
Sbjct 2184 NSPTVREYVKWGMG-----KIVTPAKLLLLRDEKQEFVAPKVVKAKAIACYCAVKWFLLY 2238
Query 2155 QLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLS 2214
+T++++ T +A K KLC A N +++ +S + + +
Sbjct 2239 CFSWIKFNTDNKVI--YTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVF 2293
Query 2215 ICLGSLICVTAAFG-VLLSNFGA-PSYCNGVRELYLNSSNVTTM-------------DFC 2259
+ + + L N G P++ + + + V+T+ FC
Sbjct 2294 LLWFNFLYANVILSDFYLPNIGPLPTFVGQIVAWFKTTFGVSTICDFYQVTDLGYRSSFC 2353
Query 2260 EGSFPCSICLSGLDSLDSYPALETIQVTISSYK--LDLTILGLAAEWVLAYMLFTKFFYL 2317
GS C +C SG D LD+Y A+ +Q + +++ L E V+ Y L+T FY
Sbjct 2354 NGSMVCELCFSGFDMLDNYDAINVVQHVVDRRLSFDYISLFKLVVELVIGYSLYTVCFYP 2413
Query 2318 LGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYV 2375
L + MQ+ + F+ + W + + M P ++R YI + Y ++
Sbjct 2414 LFVLIGMQLLTTWLPEFFMLETMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVYCLCR 2473
Query 2376 HIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTF 2435
H+M GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNCLNC+++
Sbjct 2474 HVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNCNSW 2533
Query 2436 CTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPL 2495
G+TFI+ E A DLS + KRP+NPTD + Y V V ++ L++++ GQ+ Y+
Sbjct 2534 KPGNTFITHEAAADLSKELKRPVNPTDSAYYSVTEVKQVGCSMRLFYERDGQRVYDDVNA 2593
Query 2496 SHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVS 2555
S FV+++ L + KG +V+V + ++ D++ A+V+Y+Q + +P+L++++ L++
Sbjct 2594 SLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLGAAVFYAQSLYRPMLMVEKKLIT 2651
Query 2556 DVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAAR 2615
VS MFD YVD+ V + L + V AH+ L +GV L+ V+ TF+ AR
Sbjct 2652 TANTGLSVSRTMFDLYVDSLLNVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFIGCAR 2711
Query 2616 QGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNAR 2674
+ +D+DV+TK + + + + ++ ++ T +SCNN + TY K + + DLG I NA+
Sbjct 2712 RKCAIDSDVETKSITKSVMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGVLIQNNAK 2771
Query 2675 HINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTK 2734
H+ A VAK+ NV+ IW+V + LS L+ ++R A K + +LT V ++TT
Sbjct 2772 HVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEANVPILTTP 2831
Query 2735 ISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVT 2794
SLKGG + S + + A L+C + V + +MP + + D +K I +GV
Sbjct 2832 FSLKGGAVFSRMLQWLFVANLICFI---VLWALMPTYAVHKSDMQLPLYASFKVIDNGVL 2888
Query 2795 RDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREIGFIVPGLPGTVLR 2852
RD+ TD CFANK FD W+ G Y+N K+CPVV A+I ++IG + +P TVLR
Sbjct 2889 RDVSVTDACFANKFNQFDQWYESTFGLAYYRNSKACPVVVAVIDQDIGHTLFNVPTTVLR 2948
Query 2853 AINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD 2912
LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PYCY
Sbjct 2949 -YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPYCYT 3007
Query 2913 TNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEV 2971
++ + YS L P RY L + I+FP EG VRVV T YCR G CE +E
Sbjct 3008 GGVMHNASLYSSLAPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCEEAEE 3067
Query 2972 GICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIA 3031
GIC + + WVLNN +YRA+ G FCG +A +LI + LV+P+ ++AS VAG I+A
Sbjct 3068 GICFNFNRSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASSVAGAILA 3127
Query 3032 ILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTF 3091
I+V A YY +K +R FG+Y VV N +++ ++F +L + Y L +Y+ FY Y T
Sbjct 3128 IIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFYTTL 3187
Query 3092 YFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFST 3151
YF +++S + HLQW M+ I+P W IYV + H W F+ +++ + T
Sbjct 3188 YFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFSYC--RKIGTEVRSDGT 3245
Query 3152 FEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHL 3211
FEE AL TF++ KE Y KL++ + +NRYL+LYNKY+YFSG +DT +YREAAC L
Sbjct 3246 FEEMALTTFMITKESYCKLKNS--VSDVAFNRYLSLYNKYRYFSGKMDTAAYREAACSQL 3303
Query 3212 AKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3270
AKA+ F+ N+G DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G TLNGL
Sbjct 3304 AKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCIVSVTYGNMTLNGL 3363
Query 3271 WLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLK 3330
WLDD VYCPRHVIC++ DM +P+Y +LL R ++ F V +G + L V+ + MQ C L L
Sbjct 3364 WLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSGRMSLTVMSYQMQGCQLVLT 3423
Query 3331 VDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGF 3390
V NP TPKY F ++PG+TF+VLA YNG P G + +R +HTIKGSFL GSCGSVG+
Sbjct 3424 VTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVTLRSSHTIKGSFLCGSCGSVGY 3483
Query 3391 NIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA 3450
+ D V F YMH +EL TG H GTD G FYGP+ D Q Q D T T+NV+AWLYA
Sbjct 3484 VLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAWLYA 3543
Query 3451 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
A+ N WF+ + +L +FN+ AM + + D V L L++ TG+ V + AA+K
Sbjct 3544 AIFNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLAAIKR 3601
Query 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLI 3570
L +G G+ ILGS +LEDE TP DV +Q +GV Q K +++KGT W+L + I
Sbjct 3602 L-HSGFQGKQILGSCVLEDE-TPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFLFCSI 3659
Query 3571 LVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMV 3630
+ +W++F +V + L TL + + AMLL+KHKH +L ++++P L T +V
Sbjct 3660 ISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLIKHKHLYLTMYIMPVLCTFYTNYLV 3718
Query 3631 YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVL-LILMTARTVYDDAARRVWTLM 3689
S+ WL ++ Y D V+Y L++ ++ +T R++ D ++ +
Sbjct 3719 VYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLYGVVLLVAMVFVTMRSINHDVFSIMFLVG 3777
Query 3690 NVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFIT 3749
+++LV Y+G L++ + ++ + S+ Y+ TT++ LA A V +L+ T
Sbjct 3778 RLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWLAVNVLYFT 3833
Query 3750 G-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPP 3808
++ ++L Y +GY CCCY+G+ LLN FR+ LGVY+Y +S QE RYMN+ GL PP
Sbjct 3834 DVPQIKLVLLSYLCIGYVCCCYWGILSLLNSIFRMPLGVYNYKISVQELRYMNANGLRPP 3893
Query 3809 KSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQC 3868
++S +A LN KLLGIGG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SKLW C
Sbjct 3894 RNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSKLWQYC 3953
Query 3869 VQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLCEEMLDNRATLQAIA 3922
LHN+IL D + AF+K+ LL VL + AVD I + ++ + + LQA+
Sbjct 3954 STLHNEILATSDLSMAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTVLQALQ 4013
Query 3923 SEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKM 3981
SEF ++ S+ Y A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ RKLE+M
Sbjct 4014 SEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKLERM 4073
Query 3982 ADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPL 4041
AD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 4074 ADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPS 4133
Query 4042 TTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAW 4101
T+ L ++VPD + D TYA +W IQ + DAD + QL+EI++++ W
Sbjct 4134 LTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDVNS----TW 4189
Query 4102 PLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVL 4159
PL++ A R N S V LQNNEL P LR +G+ T YYN + G+ V
Sbjct 4190 PLVIAANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ--CYYNTTGTGKIVY 4247
Query 4160 ALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMV 4219
A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V
Sbjct 4248 AILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNTLARGWV 4306
Query 4220 LGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHT 4279
+G+L++TVRLQAG ATE +NS +LS CAF+VDP K Y DY+ GG P+TNCVKMLC H
Sbjct 4307 VGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIKQGGVPVTNCVKMLCDHA 4366
Query 4280 GTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVG 4339
GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV
Sbjct 4367 GTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IKDPVS 4425
Query 4340 FTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSA-ARLTPCGTGTSTD 4398
+ L + VC VCG W+ CSC + + FLNR+ G S ARL PC +G TD
Sbjct 4426 YVLTHDVCQVCGFWRDGSCSCVGTGSQF--QSKDTNFLNRIRGTSVNARLVPCASGLDTD 4483
Query 4399 VVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNL 4458
V RAFDI N AG + K NCCRFQ DE+GN LD +FVVKR + Y E+ Y L
Sbjct 4484 VQLRAFDICNANRAGIGLYYKVNCCRFQRVDEDGNKLDKFFVVKRTNLEVYNKEKECYEL 4543
Query 4459 VKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTY 4518
K+C VA H+FF F V+G VPHI R+ L+K+TM DL YALRHFD +C TLKEIL+TY
Sbjct 4544 TKECGVVAEHEFFTFDVEGSRVPHIVRKDLSKFTMLDLCYALRHFDRNDCSTLKEILLTY 4603
Query 4519 NCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDN 4578
C++ YF KKDWYDFVENPDI+ VY LG ++LL T +F DA+ +AG+VGVLTLDN
Sbjct 4604 AECEESYFQKKDWYDFVENPDIINVYKKLGPIFNRALLNTAKFADALVEAGLVGVLTLDN 4663
Query 4579 QDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWD 4638
QDL G WYDFGDFV+ PGCGV + DSYYS +MP+LT+ AL +E ++ ++D
Sbjct 4664 QDLYGQWYDFGDFVKTVPGCGVAVADSYYSYMMPMLTMCHALDSELFVNGT----YREFD 4719
Query 4639 LLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPL 4698
L++YDFT+ +L LF +YFK+W TYHPN C DDRCI+HCANFN+LFS V P T FGPL
Sbjct 4720 LVQYDFTDFKLELFTKYFKHWSMTYHPNTCECEDDRCIIHCANFNILFSMVLPKTCFGPL 4779
Query 4699 VRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLL 4758
VR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YAADPA+H AS + LL
Sbjct 4780 VRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYAADPALHVASASALL 4839
Query 4759 DKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAA 4818
D RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV+LKHFFF QDGNAA
Sbjct 4840 DLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSVDLKHFFFTQDGNAA 4899
Query 4819 ISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKW 4878
I+DY+YY+YNLPTM DI+QLLFV+EVV+KYF+ Y+GGCI A QVIVNN DKSAG+PFNK+
Sbjct 4900 ITDYNYYKYNLPTMVDIKQLLFVLEVVNKYFEIYEGGCIPATQVIVNNYDKSAGYPFNKF 4959
Query 4879 GKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNR 4938
GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI STMT R
Sbjct 4960 GKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILSTMTGR 5019
Query 4939 QFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNM 4998
FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCDRAMPN+
Sbjct 5020 MFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCDRAMPNI 5079
Query 4999 LRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAY 5058
LRI++SLVLARKH++CC+ + RFYRLANECAQVLSE+VMCGG YVKPGGTSSGDATTA+
Sbjct 5080 LRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGDATTAF 5139
Query 5059 ANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYL 5118
ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FV E+Y +L
Sbjct 5140 ANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVSEYYEFL 5199
Query 5119 RKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGP 5178
KHFSMMILSDD VVCYNS +A++G +A+I F+ VLYYQNNVFMSEAKCW ETD+ KGP
Sbjct 5200 NKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQVLYYQNNVFMSEAKCWVETDIEKGP 5259
Query 5179 HEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPL 5238
HEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVSLAIDAYPL
Sbjct 5260 HEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPL 5319
Query 5239 TKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHT 5298
H N EY +VF +YL+YI+KL+++L +LD YSV+L+ + ++ + FY+ MY
Sbjct 5320 VYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSYSVILSTCDGQKFTDETFYKNMYLRSA 5379
Query 5299 VLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDV 5358
VLQ+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VLSV+PYVCN+PGCDV
Sbjct 5380 VLQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPYVCNSPGCDV 5439
Query 5359 TDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNA 5418
DVT+LYLGGMSYYC+ HKP SF L NG VFGLYK +C GS + DFN IA+C WT
Sbjct 5440 NDVTKLYLGGMSYYCEDHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNKIASCKWTEV 5499
Query 5419 GDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLN 5478
DY+LAN CTERLKLFAAET KATEE FK Y AT+RE++SDREL LSWE+GK RPPLN
Sbjct 5500 DDYVLANECTERLKLFAAETQKATEEAFKQCYASATIREIVSDRELILSWEIGKVRPPLN 5559
Query 5479 RNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSA 5538
+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD F+LTSH V LSA
Sbjct 5560 KNYVFTGYHFTNNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFILTSHAVSSLSA 5619
Query 5539 PTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLAL 5598
PTLVPQE+Y I ++ + F +NV NYQ +GM++Y T+QGPPGTGKSH AIGLA+
Sbjct 5620 PTLVPQENYTSI-RFASVYSVPETFQNNVPNYQHIGMKRYCTVQGPPGTGKSHLAIGLAV 5678
Query 5599 YYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVF 5658
YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+C+DKFKVN T +YVF
Sbjct 5679 YYCTARVVYTAASHAAVDALCEKAHKFLNINDCTRIVPAKVRVDCYDKFKVNDTTRKYVF 5738
Query 5659 CTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL 5718
T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGDPAQLPAPR LL KGTL
Sbjct 5739 TTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGDPAQLPAPRVLLNKGTL 5798
Query 5719 EPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYK 5778
EP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA D S+ CFK++YK
Sbjct 5799 EPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYNNKLKAKNDNSSMCFKVYYK 5858
Query 5779 GVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQ 5838
G TH+ SSA+N QI ++ +FL NP+W AVFISPYNSQN VA ++LGL TQTVDS+Q
Sbjct 5859 GQTTHESSSAVNMQQIHLISKFLKANPSWSNAVFISPYNSQNYVAKRVLGLQTQTVDSAQ 5918
Query 5839 GSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNV 5898
GSEYD+VI++QT ETAHS NVNRFNVAITRAK GILC+MS L++ L FT+L + + N
Sbjct 5919 GSEYDFVIYSQTAETAHSVNVNRFNVAITRAKKGILCVMSSMQLFESLNFTTLTLDKINN 5978
Query 5899 ATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEG-LCVDIPGIPKDMTYRRLI 5957
LQ T LFKDCS+ G HP AP+ L+VD K+K G L V + +TY RLI
Sbjct 5979 PRLQ--CTTNLFKDCSRSYVGYHPAHAPSFLAVDDKYKVGGDLAVCLNVADSAVTYSRLI 6036
Query 5958 SMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGV 6017
S+MGFK++ ++GY +FITR+EAI+ VRAW+GFD EG HA RD++GTN PLQLGFSTG+
Sbjct 6037 SLMGFKLDLTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHAIRDSIGTNFPLQLGFSTGI 6096
Query 6018 NLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLK 6077
+ V TG + F + A+ PPG+QFKHLIPLM +G W+VVRI+IVQMLSD L
Sbjct 6097 DFVVEATGMFAERDGYVFKKAAARAPPGEQFKHLIPLMSRGQKWDVVRIRIVQMLSDHLV 6156
Query 6078 GLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDY 6137
L+D VV V WA FELT ++YF K+G E C +C KRATCF++ + Y CW HS DY
Sbjct 6157 DLADSVVLVTWAASFELTCLRYFAKVGREVVCSVCTKRATCFNSRTGYYGCWRHSYSCDY 6216
Query 6138 VYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVE 6197
+YNP ++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF K V+W++E
Sbjct 6217 LYNPLIVDIQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHDCFCKSVNWNLE 6276
Query 6198 YPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQP 6257
YPII +E+ VN++CR +Q ++ ++A+L +++ V +DIGNPK + CV ++KFYDA P
Sbjct 6277 YPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKG--YDFKFYDASP 6334
Query 6258 CSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCD 6317
+++ Y Y H D+F DG+C+FWNCNVD+YPANA+VCRFDTRVL+ LNLPGC+
Sbjct 6335 V---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLNKLNLPGCN 6391
Query 6318 GGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCIT 6377
GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+SATCIT
Sbjct 6392 GGSLYVNKHAFHTSPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLRSATCIT 6451
Query 6378 RCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYN 6437
RCNLGGAVC HA EYR+YL++YN +AGF+ W+YK FD YNLWNTFTRLQSLENV YN
Sbjct 6452 RCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQSLENVVYN 6511
Query 6438 VVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPE 6497
+VN GHFDG AGE P ++I V K+ DV +F+N T P NVA EL+AKR+I+P PE
Sbjct 6512 LVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAKRSIRPHPE 6571
Query 6498 IKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVE 6557
+K+ NL +D+ + V+WDY +++ ST VC TD+ SL VLFDGR
Sbjct 6572 LKLFRNLNIDVCWSHVLWDYAKDSVFCSSTYKVCKYTDL------QCIESLNVLFDGRDN 6625
Query 6558 GQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLI---GESVKTQFNYFKKVDGI 6614
G ++ F+ RNGV I +K L+ KGP +A +NGV + V+ F K D +
Sbjct 6626 GALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFAVRKDGDDV 6685
Query 6615 IQQLP-------------------------------ETYFTQSRDLEDFKPRSQMETDFL 6643
I T FTQSR L F PRS+ME DF+
Sbjct 6686 IFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRLLSSFTPRSEMEKDFM 6745
Query 6644 ELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDST 6703
+L D FI +Y L+ YAFEH+VYG F+ +GGLHL+IGLA+R Q S L +++F+ DS+
Sbjct 6746 DLDDDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRQQKSNLVIQEFVTYDSS 6805
Query 6704 VKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCK 6763
+ +YFITD +GSSK VC+VIDLLLDDFV+I+KS +L +SKVV V +D+ + FMLWC
Sbjct 6806 IHSYFITDENSGSSKSVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVDFKDFQFMLWCN 6865
Query 6764 DGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYT 6823
+ V TFYP+LQA+ W+PG MP LYK LE+ +L NYG+ +P G MMNVAKYT
Sbjct 6866 EEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPLERVNLWNYGKPITLPTGCMMNVAKYT 6925
Query 6824 QLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDAD 6883
QLCQYL+T TLAVP NMRV+H GAGSDKGVAPG+AVLRQWLP G++LVD+D+N FVSD+
Sbjct 6926 QLCQYLSTTTLAVPANMRVLHLGAGSDKGVAPGSAVLRQWLPAGSILVDNDVNPFVSDSV 6985
Query 6884 STLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIA 6943
++ G+C T+ +WDLIISDMYDP TK++ + N SK+GFFTYLC I+ KLALGGS+A
Sbjct 6986 ASYYGNCITLPFDCQWDLIISDMYDPLTKNIGEYNVSKDGFFTYLCHLIRDKLALGGSVA 7045
Query 6944 VKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANY 7003
+KITE SWNA+LY LMG F++WT F TNVNASSSE FLIG N+L K + +IDG TMHANY
Sbjct 7046 IKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNKTRTEIDGKTMHANY 7105
Query 7004 IFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRV 7063
+FWRN+ +YSLFDMSKFPLK GTAV+SLK +QIND++ SL+EKG+L++R+ +
Sbjct 7106 LFWRNSTMWNGGAYSLFDMSKFPLKAAGTAVVSLKPDQINDLVLSLIEKGKLLVRDTRKE 7165
Query 7064 VVSSDILVN 7072
V D LVN
Sbjct 7166 VFVGDSLVN 7174
Score = 350 bits (899), Expect = 2e-94, Method: Composition-based stats.
Identities = 190/995 (19%), Positives = 334/995 (34%), Gaps = 167/995 (17%)
Query 93 DGIQYGRSGITLGVLVPHVGETPIAYR-----NVLLRKNGNKGA---GGHSYGIDLKSYD 144
DG+ G +G +G VP A + ++LLRK GNKG+ G + + YD
Sbjct 158 DGVCLG-NGRFIGWFVPVTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYD 216
Query 145 LGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDG---YPLDCI 201
E D E+ N K+ A L + G +VD C G L+
Sbjct 217 FNVE---DACEEVHLNPKGKYSCKAYA-LLKGYRGVKPILFVDQYGCDYTGCLAKGLEDY 272
Query 202 KDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSA 260
D K + + D ++S E +AW +R ++ QT ++
Sbjct 273 GDLTLSEMKELFPVWR--DSLDS----------EVLVAWHVDRDPRAAMRLQTLATVRCI 320
Query 261 KKFDTFKGEC---------PKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQE 311
+ P + N+ VK + PR+ + Y E
Sbjct 321 DYVGQPTEDVVDGDVVVREPAHLLAANAIVKRL-PRLVETMLYTDSSVTEFCY-KTKLCE 378
Query 312 CNNMHLSTLMKC--NHCDEVSWQTCDFLKATCE-HCGTENLVIEGP-TTCGYLPTNAVVK 367
C + + C + CD W + + C + E + G +P V+
Sbjct 379 CGFITQFGYVDCCGDTCDFRGWVAGNMMDGFPCPGCTKNYMPWELEAQSSGVIPEGGVLF 438
Query 368 MPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRA 427
+ N E+ G FG V+ + C W+P
Sbjct 439 T-----------------QSTDTVNRESFKLYGHAVVPFGSAVY-WSPCPG---MWLPVI 477
Query 428 SADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSAF 487
+ + S ++G+T V A
Sbjct 478 WSSVKS-YSGLTYTGVVGC--------------------------------------KAI 498
Query 488 IDTIKSLDYKSFKTIVES-CGNYKVTKGKPVKGA------WNIGQQRSVLTPLCGFPSQA 540
+ ++ + V+ CGN + + N G +L + F +
Sbjct 499 VQETDAICRSLYMDYVQHKCGNLEQRAILGLDDVYHRQLLVNRGDYSLLLENVDLFVKRR 558
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
A + +P L V + + MV S +T+ + MA
Sbjct 559 AEFACKFA----TCGDGLVPLLLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMAL 614
Query 601 VTGGLVQQTSQWLSNLLGTT--------VEKLRPIFEWIEAKLSAGVEFLKDAWEILKFL 652
+ V+ ++++ + G V +R I EW + + W + L
Sbjct 615 LFMHDVKVATKYVKKVTGKLAVRFKALGVAVVRKITEWFDLAVDIAAS--AAGWLCYQ-L 671
Query 653 ITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTI---AGAKLRSLNLGEVF 709
+ G+F + G I + + + VK F+D ++ ID +++ +G + V
Sbjct 672 VNGLFAVANGVITFVQE-VPELVKNFVDKFKAFFKVLIDSMSVSILSGLTVVKTASNRVC 730
Query 710 IAQSKGLYRQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGEL--EALE 767
+A SK + K +MP+ E T L G+ V + V + L +
Sbjct 731 LAGSKVY---EVVQKSLSAYVMPVGC-SEATCLVGEIEPAVFEDDVVDVVKAPLTYQGCC 786
Query 768 TPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSP---GLLATNNVFRLKGGAPIKGV 824
P SF IV + L + + D+ + G+L F G K V
Sbjct 787 KPPTSFEKICIV------DKLYMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAG----KKV 836
Query 825 TFGED-TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKT 883
F + V ++ + ++ITF LD D VL++ CS + V+ + E VV +AV T
Sbjct 837 EFNDKPKVRKIPSTRKIKITFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVEST 896
Query 884 LQPVSD---LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEE 940
L P + + T + LD + YLFD+ G+E + RMYCSF PD+E+ C
Sbjct 897 LSPCKEHDVIGTKVCALLDRLAGDYVYLFDEGGDEVIAPRMYCSFSAPDDED-----CVA 951
Query 941 EEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWL------DDTTEQSEIEPE 994
++ + E++ +D L + + + E + + + + +
Sbjct 952 ADVVDADENQDDDAEDSAVLVADTQEEDGVAKGQVEADSEICVAHTGSQEELAEPDAVGS 1011
Query 995 PEPTP---EEPVNQFTGYLKLTDNVAIKCVDIVKE 1026
P E V + + + + A C D V
Sbjct 1012 QTPIASAEETEVGEASDREGIAEAKATVCADAVDA 1046
Score = 172 bits (437), Expect = 1e-40, Method: Composition-based stats.
Identities = 52/156 (33%), Positives = 79/156 (51%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV D++K + N VIVN AN + HG GVAGA+ + A KE+ D +K
Sbjct 1319 CITPNVCFVKGDVIKVVRLVNAEVIVNPANGRMAHGAGVAGAIAEKAGSAFIKETSDMVK 1378
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAG--EDIQLLKAAYENFNSQDILLAPLLS 1128
G VG +G L KK L++VGP+ + LL+ AY++ N D ++ L+S
Sbjct 1379 AQGVCQVGECYESAGGKLCKKVLNIVGPDARGHGKQCYSLLERAYQHINKCDNVVTTLIS 1438
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + V V + N++ ++ +
Sbjct 1439 AGIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFDVI 1474
Score = 43.5 bits (101), Expect = 0.11, Method: Composition-based stats.
Identities = 44/210 (21%), Positives = 78/210 (37%), Gaps = 21/210 (10%)
Query 1580 DVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVG 1639
++ K++ + E +T P+D T + + E+ Y + T F
Sbjct 1055 EIEKVEDSILDELQTELNAPADKTYE-DVLAFDAVCSEALSAFYAVPSDETH---FKVC- 1109
Query 1640 GLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTV 1699
G S NC+L S L+ +Q L ++F +Q+ + +AG F ++ K++
Sbjct 1110 GFYSPAIERTNCWLRSTLIVMQSLPLEFKDLEMQKLWLSYKAGYDQCFVDKLVKSVPKSI 1169
Query 1700 GEL--GDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLK 1757
G V + L S K N C C L G++A+ + G +
Sbjct 1170 ILPQGGYVADFAYFFLSQ---CSFKAYANWRCLECDM-ELKLQGLDAMFFYGDV------ 1219
Query 1758 TGVSIPCVCGRDATQYLVQQESSFVMMSAP 1787
VS C CG T L+ + + +
Sbjct 1220 --VSHMCKCGNSMT--LLSADIPYTLHFGV 1245
>sp|P0C6W7|R1AB_CVBEN Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=rep PE=3 SV=1
Length=7094
Score = 7770 bits (20161), Expect = 0.0, Method: Composition-based stats.
Identities = 2766/5625 (49%), Positives = 3689/5625 (66%), Gaps = 164/5625 (3%)
Query 1528 LSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPH 1587
++ ++K+L + + + TVD N + V + ++G+ G + DG +VTK K
Sbjct 1552 ATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCD 1607
Query 1588 VNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWA 1647
+N++GK FF + + +A D+ L Y + L + KW+ G + K A
Sbjct 1608 INYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQA 1667
Query 1648 DNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRE 1707
+NNC+++ L LQ L +KF QEA+ R+G A F +L+LA G+ D R+
Sbjct 1668 NNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRD 1727
Query 1708 TMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCG 1767
+ + +L A + CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG
Sbjct 1728 FLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCG 1786
Query 1768 RDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDG 1827
+ + V+ + F++ S PA KL +G AN + G+ + GHY H+ +++ D
Sbjct 1787 KKLI-HCVRFDVPFLICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDA 1843
Query 1828 AHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTE 1886
+++ K+++ G ++D Y K T +Y LD V E P L YY YYT+
Sbjct 1844 SNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYNPDLSQYYCDGGKYYTQ 1903
Query 1887 QPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDV 1944
+ I T + + NFKL D LN GF + E VT +P GDV
Sbjct 1904 RIIKAQFKTFEKVDGVYTNFKLI--GHTICDILNAKLGFDSSKEFVEYKVTEWPTATGDV 1961
Query 1945 VAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFE 2003
V Y +++G KP++W ++ + + + +P+ N F+
Sbjct 1962 VLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFD 2012
Query 2004 VLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKV 2063
VL V+D +++ + E E I+ ++ K +V +VI+ +K
Sbjct 2013 VLKVDDVDDGGDISESDAK----ESKEINIIKLSGVK---KPFKVEDSVIVNDDTSEIKY 2065
Query 2064 TQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFL 2123
+ L D+ ++ ++ N LS+A+ + TI + V L
Sbjct 2066 VKSLSIVDVYDMWLTGCRYVVRTANALSMAVNVPTIRKFIKFGMTLVSIPIDL-----LN 2120
Query 2124 GQAAITTSNCAKRLAQRV--FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVK 2181
+ N K + ++ N++ ++F LLF + + T +A K
Sbjct 2121 LREIKPVFNVVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---K 2173
Query 2182 SVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSY 2239
KL A N + K+S + A + + + + I F L G P++
Sbjct 2174 LTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTF 2233
Query 2240 CNGVRELYLNSSNVTT-------------MDFCEGSFPCSICLSGLDSLDSYPALETIQV 2286
+ + ++ ++ T +C GS C CL+G D LD+Y A++ +Q
Sbjct 2234 VGKIAQWIKSTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQY 2293
Query 2287 TISS--YKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLM 2342
+ +L + E +++Y L+T +FY L +Q+ + F+ ++ W +
Sbjct 2294 EADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSV 2353
Query 2343 WFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTT 2402
++S+ M P +R YI ASF ++ + H+ GC+ C+ CYKRNR+ RV+C+T
Sbjct 2354 RLLVSLANMLPAHVFMRFYIIIASFIKLFILFRHVAYGCSKPGCLFCYKRNRSLRVKCST 2413
Query 2403 IVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTD 2462
IV GM R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD
Sbjct 2414 IVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTD 2473
Query 2463 QSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDG 2522
+ + V V + L++++ GQ+TY+ S FV+ NL + KG ++V+V +
Sbjct 2474 VAYHTVTDVKQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVEN 2533
Query 2523 KSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVP 2582
+ D++ +A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V
Sbjct 2534 DA--DKANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVD 2591
Query 2583 MEKLKALVATAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLE 2641
+ L AL+ATAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE
Sbjct 2592 KKSLNALIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLE 2651
Query 2642 VTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQ 2701
+T +SCNN + TY K +N+ DLG I +A+H+ VAK VS IW+V + LS
Sbjct 2652 LTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSD 2711
Query 2702 LRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAA 2761
+ +++ A K + +LT V+V+TT SLKGG + S + +L+C +
Sbjct 2712 FQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFLLSLVCFI-- 2769
Query 2762 LVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG- 2820
+ +MP +T+ D YK + +GV RD+ D CFANK FD W+ G
Sbjct 2770 -GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGL 2828
Query 2821 -SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
Y N +CP+V A++ +++G V +P VLR LHF+ SA G CYTP
Sbjct 2829 SYYSNSMACPIVVAVVDQDLGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQ 2887
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SI 2938
I YS+F S CVL++ CT+F A G P PYCY L++ + YS L P RY L +
Sbjct 2888 ISYSNFYASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGF 2947
Query 2939 IQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGV 2998
I+FP EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG
Sbjct 2948 IRFPEVLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGR 3007
Query 2999 DAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAAN 3058
D +LI +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N
Sbjct 3008 DVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVN 3067
Query 3059 ALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWIT 3118
+++ ++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W
Sbjct 3068 VIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFC 3127
Query 3119 AIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPL 3178
+Y+ + H W F +R+ + + TFEE AL TF++ K+ Y KL++ L
Sbjct 3128 LLYISVVVSNHAFWVFAYC--RRLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSD 3183
Query 3179 TQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDF-SNSGADVLYQPPQTSITSA 3237
+NRYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F +N+G+DVLYQPP S++++
Sbjct 3184 VAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTS 3243
Query 3238 VLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDL 3297
LQSG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +L
Sbjct 3244 FLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNL 3303
Query 3298 LIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLAC 3357
L R ++ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA
Sbjct 3304 LCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAA 3363
Query 3358 YNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 3417
YNG P G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD
Sbjct 3364 YNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDF 3423
Query 3418 EGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 3477
G FYGP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+
Sbjct 3424 NGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSN 3483
Query 3478 NYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVV 3537
+ + D V + L++ TG+++ + AA+K L +NG GR I+GS EDE TP DV
Sbjct 3484 GFSQVKSDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVY 3540
Query 3538 RQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA 3597
+Q +G+ Q K ++VKG W++ + I+ +W++F +V N L T +
Sbjct 3541 QQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALC 3599
Query 3598 IAACAMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRL 3656
+ + AMLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y
Sbjct 3600 VISLAMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTY 3658
Query 3657 KDCVMYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVI 3715
D V+Y L++ ++ +T R++ D + + VI++V Y G+ L++ I + ++
Sbjct 3659 TDEVIYGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLA 3716
Query 3716 SVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
S+ Y+ M A+ I V L F ++ +++ Y F+GY CY+GLF
Sbjct 3717 SLFGTYTWTTALSMAAAKVIA-KWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFS 3775
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
L+N FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+
Sbjct 3776 LMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQF 3835
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL
Sbjct 3836 QSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVL 3895
Query 3896 LSMQGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
+ AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G
Sbjct 3896 FANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGS 3955
Query 3950 S-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQT 4008
+ + LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QT
Sbjct 3956 ANQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQT 4015
Query 4009 MLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTY 4068
MLF+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TY
Sbjct 4016 MLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 4075
Query 4069 ASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVAL 4126
A +W+IQ + D+D QL+EI S + WPL++ A R N SA LQNNEL P L
Sbjct 4076 AGNVWQIQTIQDSDGTNKQLNEI----SDDCNWPLVIIANRHNEVSATVLQNNELMPAKL 4131
Query 4127 RQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTEL 4186
+ +G QT T YYNNS G+ V A+LSD LK+ + K DG + EL
Sbjct 4132 KTQVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LEL 4188
Query 4187 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4246
+PPC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS
Sbjct 4189 DPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSL 4248
Query 4247 CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4306
CAF+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+Y
Sbjct 4249 CAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIY 4308
Query 4307 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP 4366
CR ++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC +
Sbjct 4309 CRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDT 4366
Query 4367 LMQSADASTFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRF 4425
+QS D + FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRF
Sbjct 4367 TVQSKD-TNFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRF 4425
Query 4426 QEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISR 4485
Q DE G+ LD +FVVKR ++ Y E Y VKDC VA HDFF F V+G VPHI R
Sbjct 4426 QRVDENGDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVR 4485
Query 4486 QRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYA 4545
+ LTKYTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY
Sbjct 4486 KDLTKYTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYK 4545
Query 4546 NLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDS 4605
LG ++L+ +F D + + G+VG+LTLDNQDLNG WYDFGD+V APGCGV I DS
Sbjct 4546 KLGPIFNRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADS 4605
Query 4606 YYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHP 4665
YYS +MP+LT+ AL E +++ +DL++YDFT+ +L LF++YFK+W YHP
Sbjct 4606 YYSYMMPMLTMCHALDCELYVN----NAYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHP 4661
Query 4666 NCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHN 4725
N ++C DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N
Sbjct 4662 NTVDCQDDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMN 4721
Query 4726 QDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFN 4785
DV+ H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN
Sbjct 4722 MDVDTHRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFN 4781
Query 4786 KDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVV 4845
+DFYDF +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV
Sbjct 4782 QDFYDFILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVV 4841
Query 4846 DKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVI 4905
KYF+ YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+
Sbjct 4842 YKYFEIYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVL 4901
Query 4906 PTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYG 4965
PT+TQMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYG
Sbjct 4902 PTLTQMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYG 4961
Query 4966 GWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLA 5025
GW +ML+ + DV+ P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ S RFYRLA
Sbjct 4962 GWDDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLA 5021
Query 5026 NECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIA 5085
NECAQVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI
Sbjct 5022 NECAQVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIE 5081
Query 5086 DKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLV 5145
D +R LQ RLY +YR+ VD FV E+Y +L KHFSMMILSDD VVCYNS+YA++G +
Sbjct 5082 DLSIRALQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYI 5141
Query 5146 ASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSR 5205
A+I F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYPDPSR
Sbjct 5142 ANISAFQQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPDPSR 5201
Query 5206 ILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELT 5265
ILGAGCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L
Sbjct 5202 ILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLG 5261
Query 5266 GHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPF 5325
+LD YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P
Sbjct 5262 NQILDSYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPL 5321
Query 5326 LCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLC 5385
LCCKCCYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L
Sbjct 5322 LCCKCCYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLV 5381
Query 5386 ANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEET 5445
NG VFGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE
Sbjct 5382 MNGMVFGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEA 5441
Query 5446 FKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGD 5505
FK SY AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K +
Sbjct 5442 FKQSYASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSE 5501
Query 5506 YGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYV--RITGLYPTLNISDEF 5563
+ V YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y R +Y L + F
Sbjct 5502 LTNGVYYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETF 5558
Query 5564 SSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKAL 5623
+NV NYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA
Sbjct 5559 QNNVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAY 5618
Query 5624 KYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNY 5683
K+L I+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY
Sbjct 5619 KFLNINDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNY 5678
Query 5684 DLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCR 5743
+LSV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC
Sbjct 5679 ELSVINARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCY 5738
Query 5744 RCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTR 5803
RCP EIVDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL
Sbjct 5739 RCPKEIVDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKA 5798
Query 5804 NPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN 5863
NP W KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFN
Sbjct 5799 NPLWHKAVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFN 5858
Query 5864 VAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVA-TLQAENVTGLFKDCSKIITGLHP 5922
VAITRAK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP
Sbjct 5859 VAITRAKKGILCVMSNMQLFEALQFTTLTLDKVPQAVETRVQCSTNLFKDCSKSYSGYHP 5918
Query 5923 TQAPTHLSVDIKFK-TEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEA 5981
AP+ L+VD K+K T L V + +TY RLIS+MGFK++ ++GY +FIT+EEA
Sbjct 5919 AHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEA 5978
Query 5982 IRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAK 6041
++ VRAW+GFD EG HATRD++GTN PLQLGFSTG++ V TG + F + AK
Sbjct 5979 VKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAK 6038
Query 6042 PPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFV 6101
PPG+QFKHLIPLM +G W+VVR +IVQM +D L LSD VV V WA FELT ++YF
Sbjct 6039 APPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFA 6098
Query 6102 KIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQ 6161
K+G E +C +C KRAT +++ + Y CW HSV DY+YNP ++D+QQWG+ G+L SNHD
Sbjct 6099 KVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDL 6158
Query 6162 HCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKS 6221
+C VH AHVAS DAIMTRCLAV++CF ++W+VEYPII +EL +N++CR +Q +++K+
Sbjct 6159 YCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKA 6218
Query 6222 ALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTD 6281
A+L +++ + +DIGNPKAI CV + ++KFYDAQP ++ L YS+ H D F D
Sbjct 6219 AMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSVKTLLYSFEAHKDSFKD 6273
Query 6282 GVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNL 6341
G+C+FWNCNVD+YP NA+VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +L
Sbjct 6274 GLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHL 6333
Query 6342 KQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYN 6401
K +PFFYYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR+YL++YN
Sbjct 6334 KPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYN 6393
Query 6402 MMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVY 6461
+AGF+ W+YK FD YNLWNTFT+LQSLENV YN+V GH+ G AGE P +IIN+ V
Sbjct 6394 TATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVV 6453
Query 6462 TKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREA 6521
K+D DV IF N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY RE+
Sbjct 6454 AKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARES 6513
Query 6522 PAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLT 6581
+T GVC TD+ L VLFDGR G ++ F+ + NGV I+ VK L+
Sbjct 6514 IFCSNTYGVCMYTDL------KFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLS 6567
Query 6582 PSKGPAQASVNGVTL--IGESVKTQFNYFKK----------------------------- 6610
KGP +A +NGV + +G++ + +K
Sbjct 6568 MIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNE 6627
Query 6611 ---VDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYG 6667
V G T FTQSR + F R+ ME DF+ L D FIQ+Y LE YAFEHIVYG
Sbjct 6628 PGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDLFIQKYGLEDYAFEHIVYG 6687
Query 6668 DFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLL 6727
+F+ +GGLHL+IGL +R Q S L +++F+ DS++ +YFITD ++G SK VC+VID+L
Sbjct 6688 NFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDIL 6747
Query 6728 LDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMP 6787
LDDFV ++KS +L+ +SKVV V +D+ + FMLWC D V TFYP+LQA+ W+PG +MP
Sbjct 6748 LDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMP 6807
Query 6788 NLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGA 6847
LYK +E+ L NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GA
Sbjct 6808 VLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGA 6867
Query 6848 GSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY 6907
GS+KGVAPG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMY
Sbjct 6868 GSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMY 6927
Query 6908 DPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTA 6967
DP TK++ + N SK+GFFTY+C I+ KLALGGS+A+KITE SWNA+LYKLMG+F++WT
Sbjct 6928 DPITKNIGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTV 6987
Query 6968 FVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPL 7027
F TN NASSSE FLIG NYLGKPK +IDG MHANY+FWRN+ +YSLFDM+KFPL
Sbjct 6988 FCTNANASSSEGFLIGINYLGKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPL 7047
Query 7028 KLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
KL GTAV++L+ +QINDM+YSLLEKG+L++R+ N+ V D LVN
Sbjct 7048 KLAGTAVINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDSLVN 7092
Score = 303 bits (775), Expect = 6e-80, Method: Composition-based stats.
Identities = 182/971 (19%), Positives = 328/971 (34%), Gaps = 149/971 (15%)
Query 107 LVPHVGETPIAYRNVLLRKNGNKGA-------GGHSYGIDLKSYDLGDELGTDPIEDYEQ 159
+P I + LRK G KGA GG + + K D D + +P + +
Sbjct 176 FMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSK 235
Query 160 NWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYP---LDCIKDFLARAGKSMCTLS 216
L R G YVD C G L+ D + K++ +
Sbjct 236 KAYA---------LIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIW 286
Query 217 EQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSAK-----KFDTFKGEC 270
Q + +AW R + Q+ I+S D G
Sbjct 287 SQELPFD------------VTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSV 334
Query 271 ----PKFVFPLNSKVKVIQPRVEKKKTEGFMGR--IRSVYPVASPQECNNMHLSTLMKC- 323
P V+ +S + V+ + + Y V ++C + + C
Sbjct 335 VIKEPVHVYADDSIILRQHNLVDIMSCFYMEADAVVNAFYGVD-LKDCGFVMQFGYIDCE 393
Query 324 -NHCDEVSWQTCDFLKATCE-HCGTENLVIEGP-TTCGYLPTNAVVKMPCPACQDPEIGP 380
+ CD W + + CG + + G LP N V+
Sbjct 394 QDLCDFKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHT------------ 441
Query 381 EHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADI----GSGHT 436
S A Y ++ G FGGCV+ R W+P + + G +T
Sbjct 442 -KSAAGYGGFGCKDSFTLYGQTVVYFGGCVY----WSPARNIWIPILKSSVKSYDGLVYT 496
Query 437 GITGDNVETLNEDLL---EILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKS 493
G+ G +L+ L + + L + + + +++
Sbjct 497 GVVGCKAIVKETNLICKALYLDYVQHKCGNLHQRELLGVSDVWHKQLLLNRGVYKPLLEN 556
Query 494 LDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLD 553
+DY + + S + V + + R+ + G QA D
Sbjct 557 IDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSG---QAFC----------D 603
Query 554 AANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQWL 613
A+ + + +LD +D++ L + ++ +A Q
Sbjct 604 YADKICHAVVSKSKELLD-------VSLDSLSAAIHYLNSKIVDLA-----------QHF 645
Query 614 SNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
S+ + V K+ F+ L AW + L G + +V+ I NI
Sbjct 646 SDFGTSFVSKIVHFFKTF-----TTSTALAFAWVLFHVL-HGAYIVVESDIYFV-KNIPR 698
Query 674 CVKCFIDVVNKALEMCIDQVT---IAGAKLRSLNLGEVFIAQSK------GLYRQCIRGK 724
++ +D + I G + + ++ SK GL
Sbjct 699 YASAVAQAFRSVAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERGLLHSSQLPL 758
Query 725 EQLQLLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGT 781
+ L MP KA ++ +L+G D L V + L ++ V
Sbjct 759 DVYDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPC-----GYSEPPKVAD 813
Query 782 PVCV-NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-K 838
+C+ + + + + DK + + + +R+ + VTF E TV E+ K
Sbjct 814 KICIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAG--RRVTFKEQPTVNEIASTPK 871
Query 839 NVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDL---LTNMG 895
+++ +ELD+ + +LN C V+ V+ ++ EF VV +A+ + L P +L +
Sbjct 872 TIKVFYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVS 931
Query 896 IDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTED 955
L + + +LFD+AGEE +S++YC+F P EDD EE ++E T+
Sbjct 932 AFLQKLEDNSLFLFDEAGEEVLASKLYCAFTAP----EDDDFLEESGVEEDDVEGEETD- 986
Query 956 DYQGLPLEFGASAE-TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPV--NQFTGYLKL 1012
L ++ E V E+EE + L+DT + + EE V + F +
Sbjct 987 ------LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVEMSDFADLESV 1040
Query 1013 TDNVAIKCVDI 1023
+ C +
Sbjct 1041 IQDYENVCFEF 1051
Score = 176 bits (445), Expect = 1e-41, Method: Composition-based stats.
Identities = 51/156 (33%), Positives = 78/156 (50%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDILLAPLLS 1128
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + T QV + N++ ++ +
Sbjct 1392 AGIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFDLI 1427
Score = 47.7 bits (112), Expect = 0.006, Method: Composition-based stats.
Identities = 37/150 (25%), Positives = 60/150 (40%), Gaps = 16/150 (11%)
Query 1634 KFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILA 1693
+F +V L K NNC+L SVL +Q+L +F LQ+ + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1694 Y--SNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTL 1751
+N V + G V + L L + V C C L G++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1752 SYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
VS C CG L+ + F
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPF 1192
>sp|P0C6W8|R1AB_CVBLU Replicase polyprotein 1ab OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=rep PE=3 SV=1
Length=7094
Score = 7769 bits (20158), Expect = 0.0, Method: Composition-based stats.
Identities = 2766/5625 (49%), Positives = 3690/5625 (66%), Gaps = 164/5625 (3%)
Query 1528 LSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPH 1587
++ ++K+L + + + TVD N + V + +G+ G + DG +VTK K
Sbjct 1552 ATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGENFGKSLGNVFCDGVNVTKHKCD 1607
Query 1588 VNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWA 1647
+N++GK FF + + +A D+ L Y + L + KW+ G + K A
Sbjct 1608 INYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQA 1667
Query 1648 DNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRE 1707
+NNC+++ L LQ L +KF QEA+ R+G A F +L+LA G+ D R+
Sbjct 1668 NNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRD 1727
Query 1708 TMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCG 1767
+ + +L A + CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG
Sbjct 1728 FLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCG 1786
Query 1768 RDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDG 1827
+ + V+ + F++ S PA KL +G AN + G+ + GHY H+ +++ D
Sbjct 1787 KKLI-HCVRFDVPFLICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDA 1843
Query 1828 AHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTE 1886
+++ K+++ G ++D Y K T +Y LD V E +P L YY YYT+
Sbjct 1844 SNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQ 1903
Query 1887 QPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDV 1944
+ I T + + NFKL D LN GF + E VT +P GDV
Sbjct 1904 RIIKAQFKTFEKVDGVYTNFKLI--GHTICDILNAKLGFDSSKEFVEYKVTEWPTATGDV 1961
Query 1945 VAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFE 2003
V Y +++G KP++W ++ + + + +P+ N F+
Sbjct 1962 VLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFD 2012
Query 2004 VLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKV 2063
VL V+D +++ + E E I+ ++ K +V +VI+ +K
Sbjct 2013 VLKVDDVDDGGDISESDAK----ESKEINIIKLSGVK---KPFKVEDSVIVNDDTSEIKY 2065
Query 2064 TQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFL 2123
+ L D+ ++ ++ N+LS+A+ + TI + V L
Sbjct 2066 VKSLSIVDVYDMWLTGCRYVVRTANDLSMAVNVPTIRKFIKFGMTLVSIPIDL-----LN 2120
Query 2124 GQAAITTSNCAKRLAQRV--FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVK 2181
+ N K + ++ N++ ++F LLF + + T +A K
Sbjct 2121 LREIKPVFNVVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---K 2173
Query 2182 SVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSY 2239
KL A N + K+S + A + + + + I F L G P++
Sbjct 2174 LTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTF 2233
Query 2240 CNGVRELYLNSSNVTT-------------MDFCEGSFPCSICLSGLDSLDSYPALETIQV 2286
+ + ++ ++ T +C GS C CL+G D LD+Y A++ +Q
Sbjct 2234 VGKIAQWIKSTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQY 2293
Query 2287 TISS--YKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLM 2342
+ +L + E +++Y L+T +FY L +Q+ + F+ ++ W +
Sbjct 2294 EADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSV 2353
Query 2343 WFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTT 2402
++S+ M P +R YI ASF ++ + H+ GC+ C+ CYKRNR+ RV+C+T
Sbjct 2354 RLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKPGCLFCYKRNRSLRVKCST 2413
Query 2403 IVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTD 2462
IV GM R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD
Sbjct 2414 IVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTD 2473
Query 2463 QSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDG 2522
+ + V V + L++++ GQ+TY+ S FV+ NL + KG ++V+V +
Sbjct 2474 VAYHTVTDVKQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVEN 2533
Query 2523 KSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVP 2582
+ D++ +A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V
Sbjct 2534 DA--DKANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVD 2591
Query 2583 MEKLKALVATAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLE 2641
+ L AL+ATAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE
Sbjct 2592 KKSLNALIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLE 2651
Query 2642 VTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQ 2701
+T +SCNN + TY K +N+ DLG I +A+H+ VAK VS IW+V + LS
Sbjct 2652 LTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSD 2711
Query 2702 LRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAA 2761
+ +++ A K + +LT V+V+TT SLKGG + S + +L+C +
Sbjct 2712 FQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFLLSLVCFI-- 2769
Query 2762 LVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG- 2820
+ +MP +T+ D YK + +GV RD+ D CFANK FD W+ G
Sbjct 2770 -GLWCLMPTYTVHKSDFQLPVYTSYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGL 2828
Query 2821 -SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
Y N +CP+V A++ +++G V +P VLR LHF+ SA G CYTP
Sbjct 2829 SYYSNSMACPIVVAVVDQDLGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQ 2887
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SI 2938
I YS+F S CVL++ CT+F A G P PYCY L++ + YS L P RY L +
Sbjct 2888 ISYSNFYASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGF 2947
Query 2939 IQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGV 2998
I+FP EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG
Sbjct 2948 IRFPEVLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGR 3007
Query 2999 DAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAAN 3058
D +LI +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N
Sbjct 3008 DVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVN 3067
Query 3059 ALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWIT 3118
+++ ++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W
Sbjct 3068 VIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFC 3127
Query 3119 AIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPL 3178
+Y+ + H W F +R+ + + TFEE AL TF++ K+ Y KL++ L
Sbjct 3128 LLYISVVVSNHAFWVFAYC--RRLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSD 3183
Query 3179 TQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDF-SNSGADVLYQPPQTSITSA 3237
+NRYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F +N+G+DVLYQPP S++++
Sbjct 3184 VAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTS 3243
Query 3238 VLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDL 3297
LQSG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +L
Sbjct 3244 FLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNL 3303
Query 3298 LIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLAC 3357
L R ++ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA
Sbjct 3304 LCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAA 3363
Query 3358 YNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 3417
YNG P G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD
Sbjct 3364 YNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDF 3423
Query 3418 EGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 3477
G FYGP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+
Sbjct 3424 NGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSN 3483
Query 3478 NYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVV 3537
+ + D V + L++ TG+++ + AA+K L +NG GR I+GS EDE TP DV
Sbjct 3484 GFSQVKSDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVY 3540
Query 3538 RQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA 3597
+Q +G+ Q K ++VKG W++ + I+ +W++F +V N L T +
Sbjct 3541 QQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALC 3599
Query 3598 IAACAMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRL 3656
+ + AMLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y
Sbjct 3600 VISLAMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTY 3658
Query 3657 KDCVMYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVI 3715
D V+Y L++ ++ +T R++ D + + VI++V Y G+ L++ I + ++
Sbjct 3659 TDEVIYGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLA 3716
Query 3716 SVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
S+ Y+ M A+ I V L F ++ +++ Y F+GY CY+GLF
Sbjct 3717 SLFGTYTWTTALSMAAAKVIA-KWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFS 3775
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
L+N FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+
Sbjct 3776 LMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQF 3835
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL
Sbjct 3836 QSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVL 3895
Query 3896 LSMQGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
+ AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G
Sbjct 3896 FANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGS 3955
Query 3950 S-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQT 4008
+ + LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QT
Sbjct 3956 ANQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQT 4015
Query 4009 MLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTY 4068
MLF+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TY
Sbjct 4016 MLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 4075
Query 4069 ASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVAL 4126
A +W+IQ + D+D QL+EI S + WPL++ A R N SA LQNNEL P L
Sbjct 4076 AGNVWQIQTIQDSDGTNKQLNEI----SDDCNWPLVIIANRHNEVSATVLQNNELMPAKL 4131
Query 4127 RQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTEL 4186
+ +G QT T YYNNS G+ V A+LSD LK+ + K DG + EL
Sbjct 4132 KTQVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LEL 4188
Query 4187 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4246
+PPC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS
Sbjct 4189 DPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSL 4248
Query 4247 CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4306
CAF+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+Y
Sbjct 4249 CAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIY 4308
Query 4307 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP 4366
CR ++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC +
Sbjct 4309 CRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDT 4366
Query 4367 LMQSADASTFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRF 4425
+QS D + FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRF
Sbjct 4367 TVQSKD-TNFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRF 4425
Query 4426 QEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISR 4485
Q DE G+ LD +FVVKR ++ Y E Y VKDC VA HDFF F V+G VPHI R
Sbjct 4426 QRVDENGDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVR 4485
Query 4486 QRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYA 4545
+ LTKYTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY
Sbjct 4486 KDLTKYTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYK 4545
Query 4546 NLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDS 4605
LG ++L+ +F D + + G+VG+LTLDNQDLNG WYDFGD+V APGCGV I DS
Sbjct 4546 KLGPIFNRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADS 4605
Query 4606 YYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHP 4665
YYS +MP+LT+ AL E +++ +DL++YDFT+ +L LF++YFK+W YHP
Sbjct 4606 YYSYMMPMLTMCHALDCELYVN----NAYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHP 4661
Query 4666 NCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHN 4725
N ++C DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N
Sbjct 4662 NTVDCQDDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMN 4721
Query 4726 QDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFN 4785
DV+ H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN
Sbjct 4722 MDVDTHRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFN 4781
Query 4786 KDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVV 4845
+DFYDF +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV
Sbjct 4782 QDFYDFILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVV 4841
Query 4846 DKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVI 4905
KYF+ YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+
Sbjct 4842 YKYFEIYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVL 4901
Query 4906 PTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYG 4965
PT+TQMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYG
Sbjct 4902 PTLTQMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYG 4961
Query 4966 GWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLA 5025
GW +ML+ + DV+ P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ S RFYRLA
Sbjct 4962 GWDDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLA 5021
Query 5026 NECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIA 5085
NECAQVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI
Sbjct 5022 NECAQVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIE 5081
Query 5086 DKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLV 5145
D +R LQ RLY +YR+ VD FV E+Y +L KHFSMMILSDD VVCYNS+YA++G +
Sbjct 5082 DLSIRALQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYI 5141
Query 5146 ASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSR 5205
A+I F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYPDPSR
Sbjct 5142 ANISAFQQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPDPSR 5201
Query 5206 ILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELT 5265
ILGAGCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L
Sbjct 5202 ILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLG 5261
Query 5266 GHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPF 5325
+LD YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P
Sbjct 5262 NQILDSYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPL 5321
Query 5326 LCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLC 5385
LCCKCCYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L
Sbjct 5322 LCCKCCYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLV 5381
Query 5386 ANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEET 5445
NG VFGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE
Sbjct 5382 MNGMVFGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEA 5441
Query 5446 FKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGD 5505
FK SY AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K +
Sbjct 5442 FKQSYASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSE 5501
Query 5506 YGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYV--RITGLYPTLNISDEF 5563
+ V YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y R +Y L + F
Sbjct 5502 LTNGVYYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETF 5558
Query 5564 SSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKAL 5623
+NV NYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA
Sbjct 5559 QNNVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAY 5618
Query 5624 KYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNY 5683
K+L I+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY
Sbjct 5619 KFLNINDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNY 5678
Query 5684 DLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCR 5743
+LSV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC
Sbjct 5679 ELSVINARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCY 5738
Query 5744 RCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTR 5803
RCP EIVDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL
Sbjct 5739 RCPKEIVDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKA 5798
Query 5804 NPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN 5863
NP W KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFN
Sbjct 5799 NPLWHKAVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFN 5858
Query 5864 VAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVA-TLQAENVTGLFKDCSKIITGLHP 5922
VAITRAK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP
Sbjct 5859 VAITRAKKGILCVMSNMQLFEALQFTTLTLDKVPQAVETRVQCSTNLFKDCSKSYSGYHP 5918
Query 5923 TQAPTHLSVDIKFK-TEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEA 5981
AP+ L+VD K+K T L V + +TY RLIS+MGFK++ ++GY +FIT+EEA
Sbjct 5919 AHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEA 5978
Query 5982 IRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAK 6041
++ VRAW+GFD EG HATRD++GTN PLQLGFSTG++ V TG + F + AK
Sbjct 5979 VKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAK 6038
Query 6042 PPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFV 6101
PPG+QFKHLIPLM +G W+VVR +IVQM +D L LSD VV V WA FELT ++YF
Sbjct 6039 APPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFA 6098
Query 6102 KIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQ 6161
K+G E +C +C KRAT +++ + Y CW HSV DY+YNP ++D+QQWG+ G+L SNHD
Sbjct 6099 KVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDL 6158
Query 6162 HCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKS 6221
+C VH AHVAS DAIMTRCLAV++CF ++W+VEYPII +EL +N++CR +Q +++K+
Sbjct 6159 YCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKA 6218
Query 6222 ALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTD 6281
A+L +++ + +DIGNPKAI CV + ++KFYDAQP ++ L YS+ H D F D
Sbjct 6219 AMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSVKTLLYSFEAHKDSFKD 6273
Query 6282 GVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNL 6341
G+C+FWNCNVD+YP NA+VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +L
Sbjct 6274 GLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHL 6333
Query 6342 KQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYN 6401
K +PFFYYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR+YL++YN
Sbjct 6334 KPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYN 6393
Query 6402 MMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVY 6461
+AGF+ W+YK FD YNLWNTFT+LQSLENV YN+V GH+ G AGE P +IIN+ V
Sbjct 6394 TATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVV 6453
Query 6462 TKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREA 6521
K+D DV IF N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY RE+
Sbjct 6454 AKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARES 6513
Query 6522 PAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLT 6581
+T GVC TD+ L VLFDGR G ++ F+ + NGV I+ VK L+
Sbjct 6514 IFCSNTYGVCMYTDL------KFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLS 6567
Query 6582 PSKGPAQASVNGVTL--IGESVKTQFNYFKK----------------------------- 6610
KGP +A +NGV + +G++ + +K
Sbjct 6568 MIKGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNE 6627
Query 6611 ---VDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYG 6667
V G T FTQSR + F R+ ME DF+ L D FIQ+Y LE YAFEHIVYG
Sbjct 6628 PGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDLFIQKYGLEDYAFEHIVYG 6687
Query 6668 DFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLL 6727
+F+ +GGLHL+IGL +R Q S L +++F+ DS++ +YFITD ++G SK VC+VID+L
Sbjct 6688 NFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDIL 6747
Query 6728 LDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMP 6787
LDDFV ++KS +L+ +SKVV V +D+ + FMLWC D V TFYP+LQA+ W+PG +MP
Sbjct 6748 LDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSMP 6807
Query 6788 NLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGA 6847
LYK +E+ L NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GA
Sbjct 6808 VLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGA 6867
Query 6848 GSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY 6907
GS+KGVAPG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMY
Sbjct 6868 GSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMY 6927
Query 6908 DPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTA 6967
DP TK++ + N SK+GFFTY+C I+ KLALGGS+A+KITE SWNA+LYKLMG+F++WT
Sbjct 6928 DPITKNIGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTV 6987
Query 6968 FVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPL 7027
F TN NASSSE FLIG NYLGKPK +IDG MHANY+FWRN+ +YSLFDM+KFPL
Sbjct 6988 FCTNANASSSEGFLIGINYLGKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPL 7047
Query 7028 KLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
KL GTAV++L+ +QINDM+YSLLEKG+L++R+ N+ V D LVN
Sbjct 7048 KLAGTAVINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDSLVN 7092
Score = 302 bits (774), Expect = 7e-80, Method: Composition-based stats.
Identities = 182/971 (19%), Positives = 328/971 (34%), Gaps = 149/971 (15%)
Query 107 LVPHVGETPIAYRNVLLRKNGNKGA-------GGHSYGIDLKSYDLGDELGTDPIEDYEQ 159
+P I + LRK G KGA GG + + K D D + +P + +
Sbjct 176 FMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSK 235
Query 160 NWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYP---LDCIKDFLARAGKSMCTLS 216
L R G YVD C G L+ D + K++ +
Sbjct 236 KAYA---------LIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIW 286
Query 217 EQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSAK-----KFDTFKGEC 270
Q + +AW R + Q+ I+S D G
Sbjct 287 SQELPFD------------VTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSV 334
Query 271 ----PKFVFPLNSKVKVIQPRVEKKKTEGFMGR--IRSVYPVASPQECNNMHLSTLMKC- 323
P V+ +S + V+ + + Y V ++C + + C
Sbjct 335 VIKEPVHVYADDSIILRQHNLVDIMSCFYMEADAVVNAFYGVD-LKDCGFVMQFGYIDCE 393
Query 324 -NHCDEVSWQTCDFLKATCE-HCGTENLVIEGP-TTCGYLPTNAVVKMPCPACQDPEIGP 380
+ CD W + + CG + + G LP N V+
Sbjct 394 QDLCDFKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHT------------ 441
Query 381 EHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADI----GSGHT 436
S A Y ++ G FGGCV+ R W+P + + G +T
Sbjct 442 -KSAAGYGGFGCKDSFTLYGQTVVYFGGCVY----WSPARNIWIPILKSSVKSYDGLVYT 496
Query 437 GITGDNVETLNEDLL---EILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKS 493
G+ G +L+ L + + L + + + +++
Sbjct 497 GVVGCKAIVKETNLICKALYLDYVQHKCGNLHQRELLGVSDVWHKQLLLNRGVYKPLLEN 556
Query 494 LDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLD 553
+DY + + S + V + + R+ + G QA D
Sbjct 557 IDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSG---QAFC----------D 603
Query 554 AANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQWL 613
A+ + + +LD +D++ L + ++ +A Q
Sbjct 604 YADKICHAVVSKSKELLD-------VSLDSLSAAIHYLNSKIVDLA-----------QHF 645
Query 614 SNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
S+ + V K+ F+ L AW + L G + +V+ I NI
Sbjct 646 SDFGTSFVSKIVHFFKTF-----TTSTALAFAWVLFHVL-HGAYIVVESDIYFV-KNIPR 698
Query 674 CVKCFIDVVNKALEMCIDQVT---IAGAKLRSLNLGEVFIAQSK------GLYRQCIRGK 724
++ +D + I G + + ++ SK GL
Sbjct 699 YASAVAQAFRSVAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERGLLHSSQLPL 758
Query 725 EQLQLLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGT 781
+ L MP KA ++ +L+G D L V + L ++ V
Sbjct 759 DVYDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPC-----GYSEPPKVAD 813
Query 782 PVCV-NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-K 838
+C+ + + + + DK + + + +R+ + VTF E TV E+ K
Sbjct 814 KICIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAG--RRVTFKEQPTVNEIASTPK 871
Query 839 NVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDL---LTNMG 895
+++ +ELD+ + +LN C V+ V+ ++ EF VV +A+ + L P +L +
Sbjct 872 TIKVFYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVVDAIEEKLSPCKELEGVGAKVS 931
Query 896 IDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTED 955
L + + +LFD+AGEE +S++YC+F P EDD EE ++E T+
Sbjct 932 AFLQKLEDNSLFLFDEAGEEVLASKLYCAFTAP----EDDDFLEESGVEEDDVEGEETD- 986
Query 956 DYQGLPLEFGASAE-TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPV--NQFTGYLKL 1012
L ++ E V E+EE + L+DT + + EE V + F +
Sbjct 987 ------LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVEMSDFADLESV 1040
Query 1013 TDNVAIKCVDI 1023
+ C +
Sbjct 1041 IQDYENVCFEF 1051
Score = 176 bits (445), Expect = 1e-41, Method: Composition-based stats.
Identities = 51/156 (33%), Positives = 78/156 (50%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDILLAPLLS 1128
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + T QV + N++ ++ +
Sbjct 1392 AGIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFDLI 1427
Score = 47.7 bits (112), Expect = 0.006, Method: Composition-based stats.
Identities = 37/150 (25%), Positives = 60/150 (40%), Gaps = 16/150 (11%)
Query 1634 KFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILA 1693
+F +V L K NNC+L SVL +Q+L +F LQ+ + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1694 Y--SNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTL 1751
+N V + G V + L L + V C C L G++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1752 SYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
VS C CG L+ + F
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPF 1192
>sp|P0C6Y0|R1AB_CVMJH Replicase polyprotein 1ab OS=Murine coronavirus
(strain JHM) OX=11144 GN=rep PE=1 SV=1
Length=7180
Score = 7759 bits (20132), Expect = 0.0, Method: Composition-based stats.
Identities = 2733/5655 (48%), Positives = 3643/5655 (64%), Gaps = 179/5655 (3%)
Query 1526 EVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIK 1585
+ S+ ++++LL + V TVD N + V +G+ G + DG +VTK++
Sbjct 1595 KEASVSQIRALL----ANKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR 1650
Query 1586 PHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIK 1645
H+GK FF A + DE L +Y S L KW G + K
Sbjct 1651 CSAIHKGKVFFQYSGLSAADLAAVKDAFGFDEPQLLQYYSMLGMC-KWPVVVCGNYFAFK 1709
Query 1646 WADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDV 1705
++NNCY++ L LQ L +KF + R+G F +L+LA + E D
Sbjct 1710 QSNNNCYINVACLMLQHLSLKFPKWQWRRPGNEFRSGKPLRFVSLVLAKGSFKFNEPSDS 1769
Query 1706 RETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCV 1765
+ + L+ A+L A L +CK CG K GV+AVM+ GTL L G +I C
Sbjct 1770 TDFIRVELREADLSGATCDLEFICK-CGVKQEQRKGVDAVMHFGTLDKSGLVKGYNIACT 1828
Query 1766 CGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRI 1825
CG + Q F++ S P KL + AN +TG GHYTH+ K
Sbjct 1829 CGDKLV-HCTQFNVPFLICSNTPEGKKLPDDV-VAANIFTGG-SVGHYTHVKCKPKYQLY 1885
Query 1826 DGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYY 1884
D +++K+SE KG TD Y K T + +Y LD V +P L YY + YY
Sbjct 1886 DACNVSKVSEAKGNFTDCLYLKNLKQTFSSVLTTYYLDDVKCVAYKPDLSQYYCESGKYY 1945
Query 1885 TEQPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNG 1942
T+ I T + NFKL + A+ LN GF E +T +P G
Sbjct 1946 TKPIIKAQFRTFEKVEGVYTNFKLVGHD--IAEKLNAKLGFDCNSPFMEYKITEWPTATG 2003
Query 1943 DVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF----KPNTWCLRCLWSTKPVDT 1998
DVV Y + + G KP++W ++ + + +P+ C ++ PVD
Sbjct 2004 DVVLASDDLYVSRYSGGCVTFGKPVIWRGHEEASLKSLTYFNRPSVVCEN-KFNVLPVDV 2062
Query 1999 SNSFE--------------------VLAVEDTQGMDNLACESQQPTSEEVVENP------ 2032
S + ++ E + AC S + V+E
Sbjct 2063 SEPTDRRPVPSAVLVTGAASGADASAISTEPGTAKEQKACASDSVEDQIVMEAQKKSSVT 2122
Query 2033 -TIQKEVIECDVKTT-EVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNEL 2090
KEV VK + +V++ KV + L D+ ++ + NEL
Sbjct 2123 TVAVKEVKLNGVKKPVKWNCSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWTANEL 2182
Query 2091 SLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVF 2150
S + T+ + + SK++ L + K + + Y +
Sbjct 2183 SRLINSPTVREYVKWGM-----SKLIIPANLLLLRDEKQEFVAPKVVKAKAIACYGAVKW 2237
Query 2151 TLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWL 2210
LL+ +T++++ T +A K KLC A N +++ +S + +
Sbjct 2238 FLLYCFSWIKFNTDNKVI--YTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLV 2292
Query 2211 LLLSICLGSLICVTAAFG-VLLSNFGA-PSYCNGVRELYLNSSNVTTM------------ 2256
+ + + + L N G P + + + V T+
Sbjct 2293 ATVFLLWFNFLYANVILSDFYLPNIGPLPMFVGQIVAWVKTTFGVLTICDFYQVTDLGYR 2352
Query 2257 -DFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK--LDLTILGLAAEWVLAYMLFTK 2313
FC GS C +C SG D LD+Y ++ +Q + +++ L E V+ Y L+T
Sbjct 2353 SSFCNGSMVCELCFSGFDMLDNYESINVVQHVVDRRVSFDYISLFKLVVELVIGYSLYTV 2412
Query 2314 FFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFASFYYIW 2371
FY L + MQ+ + F+ + W + + M P ++R YI + Y ++
Sbjct 2413 CFYPLFVLVGMQLLTTWLPEFFMLGTMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVY 2472
Query 2372 KSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLN 2431
H+M GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNCLN
Sbjct 2473 CLCRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLN 2532
Query 2432 CDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYE 2491
C+++ G+TFI+ E A DLS + KRP+NPTD + Y V V ++ L++++ GQ+ Y+
Sbjct 2533 CNSWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVIEVKQVGCSMRLFYERDGQRVYD 2592
Query 2492 RHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQ 2551
S FV+++ L + KG +V+V + ++ D++ +A+V+Y+Q + +P+L++++
Sbjct 2593 DVSASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRPMLMVEK 2650
Query 2552 ALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFV 2611
L++ VS MFD YV + V + L + V AH+ L +GV L+ V+ TFV
Sbjct 2651 KLITTANTGLSVSRTMFDLYVYSLLRHLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFV 2710
Query 2612 SAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACID 2670
AR+ +D+DV+TK + + + + ++ +EVT +SCNN + TY K + + DLG I
Sbjct 2711 GCARRKCAIDSDVETKSITKSVMAAVNAGVEVTDESCNNLVPTYVKSDTIVAADLGVLIQ 2770
Query 2671 CNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNV 2730
NA+H+ + VAK+ NV+ IW+V + LS L+ ++R A K + +LT V +
Sbjct 2771 NNAKHVQSNVAKAANVACIWSVDAFNQLSADLQHRLRKACVKTGLKIKLTYNKQEANVPI 2830
Query 2731 ITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
+TT SLKGG + S + + A L+C + V + +MP + + D +K I
Sbjct 2831 LTTPFSLKGGAVFSRVLQWLFVANLICFI---VLWALMPTYAVHKSDMQLPLYASFKVID 2887
Query 2791 DGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREIGFIVPGLPG 2848
+GV RD+ TD CFANK FD W+ G Y+N K+CPVV A+I ++IG + +P
Sbjct 2888 NGVLRDVSVTDACFANKFNQFDQWYESTFGLVYYRNSKACPVVVAVIDQDIGHTLFNVPT 2947
Query 2849 TVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVP 2908
VLR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P P
Sbjct 2948 KVLR-YGFHVLHFITHAFATDRVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHP 3006
Query 2909 YCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRHGTCE 2967
YCY ++ + YS L P RY L + I+FP EG VRVV T YCR G CE
Sbjct 3007 YCYTEGVMHNASLYSSLVPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCE 3066
Query 2968 RSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAG 3027
+E GIC + + WVLNN +YRA+ G FCG +A +LI + LVQP+ ++AS VAG
Sbjct 3067 EAEEGICFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVQPIDFFALTASSVAG 3126
Query 3028 GIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYL 3087
I+AI+V A YY +K +R FG+Y VV N +++ ++F +L + Y L +Y+ FY
Sbjct 3127 AILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYF 3186
Query 3088 YLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGV 3147
Y T YF +++S + HLQW M+ I+P W YV + H W F+ +++ +
Sbjct 3187 YTTLYFPSEISVVMHLQWLVMYGAIMPLWFCITYVAVVVSNHALWLFSYC--RKIGTDVR 3244
Query 3148 TFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAA 3207
+ TFEE AL TF++ KE Y KL++ + +NRYL+LYNKY+YFSG +DT +YREAA
Sbjct 3245 SDGTFEEMALTTFMITKESYCKLKNS--VSDVAFNRYLSLYNKYRYFSGKMDTATYREAA 3302
Query 3208 CCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT 3266
C LAKA+ F+ N+G DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G T
Sbjct 3303 CSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCVVSVTYGNMT 3362
Query 3267 LNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCL 3326
LNGLWLDD VYCPRHVIC++ DM +P+Y +LL R ++ F V + + L V+ + MQ L
Sbjct 3363 LNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSDRMSLTVMSYQMQGSL 3422
Query 3327 LRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCG 3386
L L V NP TPKY F ++PG+TF+VLA YNG P G + MR +HTIKGSFL GSCG
Sbjct 3423 LVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVVMRSSHTIKGSFLCGSCG 3482
Query 3387 SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLA 3446
SVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q Q D T T+NV+A
Sbjct 3483 SVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVA 3542
Query 3447 WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA 3506
WLYAA++N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A
Sbjct 3543 WLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLA 3600
Query 3507 ALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLT 3566
A+K L +G G+ ILGS +LEDE TP DV +Q +GV Q K +++KGT W+L +
Sbjct 3601 AIKRL-HSGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFL 3659
Query 3567 SLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAY 3626
I+ +W++F +V + L TL + AMLL+KHKH +L ++++P L T+ Y
Sbjct 3660 FCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVIFAMLLIKHKHLYLTMYIMPVLCTLFY 3718
Query 3627 FNMVY--MPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVL-LILMTARTVYDDAAR 3683
N + S+ WL ++ Y D V+Y L++ ++ +T R++ D
Sbjct 3719 TNYLVVGYKQSFRGLAYAWLSYFVPAVD-YTYMDEVLYGVVLLVAMVFVTMRSINHDVFS 3777
Query 3684 RVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYY 3743
++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA A V
Sbjct 3778 TMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWLAV 3833
Query 3744 PLLFITG-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNS 3802
+L+ T ++ ++L Y +GY CCCY+G+ LLN FR+ LGVY+Y +S QE RYMN+
Sbjct 3834 NVLYFTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYMNA 3893
Query 3803 QGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSS 3862
GL PP++S +A LN KLLGIGG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+S
Sbjct 3894 NGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNS 3953
Query 3863 KLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLCEEMLDNRA 3916
KLW C LHN+IL D + AF+K+ LL VL + AVD I + ++ + +
Sbjct 3954 KLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNT 4013
Query 3917 TLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQ 3975
LQA+ SEF ++ S+ Y A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+
Sbjct 4014 VLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVA 4073
Query 3976 RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP 4035
RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVP
Sbjct 4074 RKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVP 4133
Query 4036 LNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDN 4095
LN IP T+ L ++VPD + D TYA +W IQ + DAD + QL+EI++++
Sbjct 4134 LNAIPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVNS 4193
Query 4096 SPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSK 4153
WPL+++A R N S V LQNNEL P LR +G+ YYN +
Sbjct 4194 ----TWPLVISANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNIPTQ--CYYNTTG 4247
Query 4154 GGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNN 4213
G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N
Sbjct 4248 TGKIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNT 4306
Query 4214 LNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVK 4273
L RG V+G+L++TVRLQAG ATE +NS +LS CAF+VDP K Y DY+ GG P+TNCVK
Sbjct 4307 LARGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIQQGGVPVTNCVK 4366
Query 4274 MLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTC 4333
MLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4367 MLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG- 4425
Query 4334 ANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSA-ARLTPCG 4392
DPV + L + VC VCG W+ CSC + + FLNRV G S ARL PC
Sbjct 4426 IKDPVSYVLTHDVCQVCGFWRDGSCSCVGTGSQF--QSKDTNFLNRVRGTSVNARLVPCA 4483
Query 4393 TGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHE 4452
+G TDV RAFDI N AG + K NC RFQ DEEGN LD +FVVKR + Y E
Sbjct 4484 SGLDTDVQLRAFDICNANRAGIGLYYKVNCFRFQRVDEEGNKLDKFFVVKRTNLEVYNKE 4543
Query 4453 ETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLK 4512
+ Y L KDC VA H+FF F V+G VPHI R+ L+K+TM DL YALRHFD +C TLK
Sbjct 4544 KECYELTKDCGVVAEHEFFTFDVEGSRVPHIVRKDLSKFTMLDLCYALRHFDRNDCSTLK 4603
Query 4513 EILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVG 4572
EIL+TY CD+ YF KKDWYDFVENPDI+ VY LG ++LL T F D + +AG+VG
Sbjct 4604 EILLTYAECDESYFQKKDWYDFVENPDIINVYKKLGPIFNRALLNTANFADTLVEAGLVG 4663
Query 4573 VLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAK 4632
VLTLDNQDL G WYDFGDFV+ P CGV + DSYYS +MP+LT+ AL +E ++
Sbjct 4664 VLTLDNQDLYGQWYDFGDFVKTVPCCGVAVADSYYSYMMPMLTMCHALDSELFVNGT--- 4720
Query 4633 PLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPP 4692
++DL++YDFT+ +L LF++YFK+W TYHPN C DDRCI+HCANFN+LFS V P
Sbjct 4721 -YREFDLVQYDFTDFKLELFNKYFKHWSMTYHPNTSECEDDRCIIHCANFNILFSMVLPK 4779
Query 4693 TSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAA 4752
T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+LL+YAADPA+H A
Sbjct 4780 TCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNMDVDTHRYRLSLKDLLLYAADPALHVA 4839
Query 4753 SGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFA 4812
S + LLD RT CFSVAA+T+ V FQTVKPGNFN+DFY+F +SKG KEGSSV+LKHFFF
Sbjct 4840 SASALLDLRTCCFSVAAITSGVKFQTVKPGNFNQDFYEFILSKGLLKEGSSVDLKHFFFT 4899
Query 4813 QDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAG 4872
QDGNAAI+DY+YY+YNLPTM DI+QLLFVVEVV+KYF+ Y+GGCI A QVIVNN DKSAG
Sbjct 4900 QDGNAAITDYNYYKYNLPTMVDIKQLLFVVEVVNKYFEIYEGGCIPATQVIVNNYDKSAG 4959
Query 4873 FPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSIC 4932
+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI
Sbjct 4960 YPFNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSIL 5019
Query 4933 STMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCD 4992
STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCD
Sbjct 5020 STMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCD 5079
Query 4993 RAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSG 5052
RAMPN+LRI++SLVLARKH++CC+ + RFYRLANECAQVL E+VMCGG YVKPGGTSSG
Sbjct 5080 RAMPNILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLGEIVMCGGCYYVKPGGTSSG 5139
Query 5053 DATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVD 5112
DATTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FV
Sbjct 5140 DATTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVS 5199
Query 5113 EFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTET 5172
E+Y +L KHFSM+ILSDD VVCYNS +A++G +A+I +F+ VLYYQNNVFMSEAKCW ET
Sbjct 5200 EYYEFLNKHFSMIILSDDGVVCYNSEFASKGYIANISDFQQVLYYQNNVFMSEAKCWVET 5259
Query 5173 DLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLA 5232
D+ KGPHEFCSQHTMLVK D VYLPYPDPSRILGAGCFVDD++KTD L+IERFVSLA
Sbjct 5260 DIEKGPHEFCSQHTMLVKMDGDEVYLPYPDPSRILGAGCFVDDLLKTDSVLLIERFVSLA 5319
Query 5233 IDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEA 5292
IDAYPL H N EY +VF +YL+YI+KL+++L +LD SV+L+ + ++ + FY+
Sbjct 5320 IDAYPLVYHENPEYQNVFRVYLEYIKKLYNDLGNQILDSISVILSTCDGQKFTDETFYKN 5379
Query 5293 MYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCN 5352
MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKC YDHV+ST HK VLSV+PYVCN
Sbjct 5380 MYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCAYDHVMSTDHKYVLSVSPYVCN 5439
Query 5353 APGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIAT 5412
+PGCDV DVT+LYLGGMSYYC++HKP SF L NG VFGLYK +C GS + DFN IA+
Sbjct 5440 SPGCDVNDVTKLYLGGMSYYCEAHKPQYSFKLVMNGMVFGLYKQSCTGSPYIEDFNKIAS 5499
Query 5413 CDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGK 5472
C WT DY+LAN CTERLKLFAAET KATEE FK Y AT+RE++SDREL LSWE+GK
Sbjct 5500 CKWTEVDDYVLANECTERLKLFAAETQKATEEAFKQCYASATIREIVSDRELILSWEIGK 5559
Query 5473 PRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHT 5532
RPPLN+NYVFTGY T N K +GEY F+K + + V YR TTTYKL+VGD F+LTSH
Sbjct 5560 VRPPLNKNYVFTGYHFTNNGKTVLGEYVFDKSELTNGVYYRATTTYKLSVGDVFILTSHA 5619
Query 5533 VMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHF 5592
V LSAPTLVPQE+Y + ++ + F +NV NYQ +G+++Y T+QGPPGTGKSH
Sbjct 5620 VSSLSAPTLVPQENYTSV-RFASAYSVPETFQNNVPNYQHIGIKRYCTVQGPPGTGKSHL 5678
Query 5593 AIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNST 5652
AIG A+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RI+PA+ RV+C+DKF VN T
Sbjct 5679 AIGHAVYYCTARVVYTAASHAAVDALCEKAHKFLNINDCARIVPAKLRVDCYDKFNVNDT 5738
Query 5653 LEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTL 5712
+YVF T+NALPE DI+V DE+SM TNY+LSV+N+R+RAKHYVYIGDPAQLPAPR L
Sbjct 5739 TRKYVFTTINALPELVTDIIVVDEVSMLTNYELSVINSRVRAKHYVYIGDPAQLPAPRVL 5798
Query 5713 LTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQC 5772
L KGTLEP YFNSV +LM +GPD+FLGTC RCP EIVDTVSALVY+NKLKA D SA C
Sbjct 5799 LNKGTLEPRYFNSVTKLMCCLGPDIFLGTCYRCPKEIVDTVSALVYNNKLKAKNDNSAMC 5858
Query 5773 FKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQ 5832
FK++YKG TH+ SSA+N QI ++ + L NP+W AVFISPYNSQN VA ++LGL TQ
Sbjct 5859 FKVYYKGQTTHESSSAVNMQQIHLISKLLKANPSWSNAVFISPYNSQNYVAKRVLGLQTQ 5918
Query 5833 TVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLE 5892
T DS+QGS YD+VI++QT +TAHS NVNRFNVAITRAK GILC+MS L FT+L
Sbjct 5919 TADSAQGSAYDFVIYSQTAQTAHSVNVNRFNVAITRAKKGILCVMSSMQLIGVFNFTTLT 5978
Query 5893 IPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEG-LCVDIPGIPKDM 5951
+ + N LQ T LFKDCSK G+ P L+VD K+K G L V + +
Sbjct 5979 LDKINNPRLQ--CTTNLFKDCSKSYVGIPP--CAFLLAVDDKYKVSGNLAVCLNVADSAV 6034
Query 5952 TYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQL 6011
TY RLIS+MGFK++ ++GY +FITR+EAI+ VRAW+GFD EG HATRD++GTN PLQL
Sbjct 6035 TYSRLISLMGFKLDLTLDGYCKLFITRDEAIKRVRAWVGFDAEGAHATRDSIGTNFPLQL 6094
Query 6012 GFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQM 6071
GFSTG++ V TG + F + A+ PPG+QFKHL+PLM +G W+VVRI+IVQM
Sbjct 6095 GFSTGIDFVVEATGMFAERDGYVFKKAAARAPPGEQFKHLVPLMSRGQKWDVVRIRIVQM 6154
Query 6072 LSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNH 6131
LSD L L+D VV V WA FELT ++YF K+G E C +C+KRATCF++ + Y CW H
Sbjct 6155 LSDHLVDLADSVVLVTWAASFELTCLRYFAKVGKEVVCSVCNKRATCFNSRTGYYGCWRH 6214
Query 6132 SVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKR 6191
S DY+YNP ++D+QQWG+TG+L SNHD C VH AHVAS DAIMTRCLAVH+CF K
Sbjct 6215 SYSCDYLYNPLIVDIQQWGYTGSLTSNHDPICSVHKGAHVASSDAIMTRCLAVHDCFCKS 6274
Query 6192 VDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWK 6251
V+W++EYPII +E+ VN++CR +Q ++ ++A+L +++ V +DIGNPK + CV ++K
Sbjct 6275 VNWNLEYPIISNEVSVNTSCRLLQRVMFRAAMLCNRYDVCYDIGNPKGLACVKG--YDFK 6332
Query 6252 FYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNL 6311
FYDA P +++ Y Y H D+F DG+C+FWNCNVD+YPANA+VCRFDTRVLS L
Sbjct 6333 FYDASPV---VKSVKQFVYKYEAHKDQFLDGLCMFWNCNVDKYPANAVVCRFDTRVLSKL 6389
Query 6312 NLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLK 6371
NLPGC+GGSLYVNKHAFHT F ++AF NLK +PFFYYSD+PC +DYVPL+
Sbjct 6390 NLPGCNGGSLYVNKHAFHTNPFTRAAFENLKPMPFFYYSDTPCVYMEGMESKQVDYVPLR 6449
Query 6372 SATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSL 6431
SATCITRCNLGGAVC HA EYR+YL++YN +AGF+ W+YK FD YNLWNTFTRLQSL
Sbjct 6450 SATCITRCNLGGAVCLKHAEEYREYLESYNTATTAGFTFWVYKTFDFYNLWNTFTRLQSL 6509
Query 6432 ENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRN 6491
ENV YN+VN GHFDG AGE P ++I V K+ DV +F+N T P NVA EL+A+R+
Sbjct 6510 ENVVYNLVNAGHFDGRAGELPCAVIGEKVIAKIQNEDVVVFKNNTPFPTNVAVELFAERS 6569
Query 6492 IKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVL 6551
I+P PE+K+ + + + N V+WDY +++ ST VC TD+ SL VL
Sbjct 6570 IRPHPELKLFRSSNIHVCWNHVLWDYAKDSVFCSSTYKVCKYTDL------QCIESLNVL 6623
Query 6552 FDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLI---GESVKTQFNYF 6608
FDGR G ++ F+ RNGV I +K L+ KGP +A +NGV + V+ F
Sbjct 6624 FDGRDNGALEAFKKCRNGVYINTTKIKSLSMIKGPQRADLNGVVVEKVGDSDVEFWFAMR 6683
Query 6609 KKVDGIIQQLP-------------------------------ETYFTQSRDLEDFKPRSQ 6637
+ D +I T FTQSR L F PRS+
Sbjct 6684 RDGDDVIFSRTGSLEPSHYRSPQGNPGGNRVGDLSGNEALARGTIFTQSRFLSSFSPRSE 6743
Query 6638 METDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDF 6697
ME DF++L D FI +Y L+ YAFEH+VYG F+ +GGLHL+IGLA+R + S L +++F
Sbjct 6744 MEKDFMDLDEDVFIAKYSLQDYAFEHVVYGSFNQKIIGGLHLLIGLARRPKKSNLVIQEF 6803
Query 6698 IPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEIS 6757
+P DS++ +YFITD +GSS+ VC+VIDLLLDDFV+I+KS +L +SKVV V +D+ +
Sbjct 6804 VPYDSSIHSYFITDENSGSSESVCTVIDLLLDDFVDIVKSLNLKCVSKVVNVNVDFKDFQ 6863
Query 6758 FMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMM 6817
FMLWC + V TFYP+LQA+ W+PG MP LYK +E+ +L NYG+ +P G MM
Sbjct 6864 FMLWCNEEKVMTFYPRLQAAADWKPGYVMPVLYKYLESPMERVNLWNYGKPITLPTGCMM 6923
Query 6818 NVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLND 6877
NVAKYTQLCQYL+T TLAVP NMRV+H GAGSDKGVAPG+AVLRQWLP+G++LVD+D+N
Sbjct 6924 NVAKYTQLCQYLSTTTLAVPANMRVLHLGAGSDKGVAPGSAVLRQWLPSGSILVDNDMNP 6983
Query 6878 FVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLA 6937
FVSD+ ++ G+C T+ +WDLIISDMYDP TK++ + N SK+GFFTYLC I+ KLA
Sbjct 6984 FVSDSVASYYGNCITLPFDCQWDLIISDMYDPLTKNIGEYNVSKDGFFTYLCHLIRDKLA 7043
Query 6938 LGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQIDGY 6997
LGGS+A+KITE SWNA+LY LMG F++WT F TNVNASSSE FLIG N+L + + +IDG
Sbjct 7044 LGGSVAIKITEFSWNAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNRTRNEIDGK 7103
Query 6998 TMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLII 7057
TMHANY+FWRN+ +YSLFDM+KFPLK GTAV+SLK +QIND++ SL+EKG+L++
Sbjct 7104 TMHANYLFWRNSTMWNGGAYSLFDMTKFPLKAAGTAVVSLKPDQINDLVLSLIEKGKLLV 7163
Query 7058 RENNRVVVSSDILVN 7072
R+ + V D LVN
Sbjct 7164 RDTRKEVFVGDSLVN 7178
Score = 355 bits (912), Expect = 6e-96, Method: Composition-based stats.
Identities = 202/997 (20%), Positives = 335/997 (34%), Gaps = 172/997 (17%)
Query 93 DGIQYGRSGITLGVLVPHVGETPIAYR-----NVLLRKNGNKGA---GGHSYGIDLKSYD 144
DG+ G +G +G VP A + ++LLRK GNKG+ G + + YD
Sbjct 158 DGVCLG-NGRFIGWFVPVTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYD 216
Query 145 LGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDG---YPLDCI 201
E D E+ N K+ A L R G +VD C G L+
Sbjct 217 FNVE---DACEEVHLNPRGKYSCKAYA-LLRGYRGVKPILFVDQYGCDYTGCLAKGLEDY 272
Query 202 KDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSA 260
D TLSE + R D+E +AW +R ++ QT ++S
Sbjct 273 GDL---------TLSEMKELSPVWR---DSLDNEVVVAWHVDRDPRAVMRLQTLATVRSI 320
Query 261 KKF-----DTFKGEC----PKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQE 311
+ D G+ P + N+ VK + PR+ + Y +
Sbjct 321 EYVGQPIEDMVDGDVVMREPAHLLAPNAIVKRL-PRLVETMLYTDSSVTEFCY-KTKLCD 378
Query 312 CNNMHLSTLMKC--NHCDEVSWQTCDFLKATCE-HCGTENLVIEGP-TTCGYLPTNAVVK 367
C + + C + C W + + C + E + G +P V+
Sbjct 379 CGFITQFGYVDCCGDTCGFRGWVPGNMMDGFPCPGCCKSYMPWELEAQSSGVIPEGGVLF 438
Query 368 MPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRA 427
+ N E+ G FGG AY Y W+P
Sbjct 439 T-----------------QSTDTVNRESFKLYGHAVVPFGGA--AYWSPYPGM--WLPVI 477
Query 428 SADIGS----GHTGITG-DNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSA 482
+ + S +TG+ G + + + L ++ V N E IL
Sbjct 478 WSSVKSYSYLTYTGVVGCKAIVQETDAICRFLY-----MDYVQHKCGNLEQRAIL----- 527
Query 483 STSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAG 542
LD + ++ + G+Y + N+
Sbjct 528 ----------GLDDVYHRQLLVNRGDYSLLL-------ENVDLF---------------- 554
Query 543 VIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDA-------MVYTSDLLTNSV 595
R + A +LDG+ +S L+ + MV S + +
Sbjct 555 -----VKRRAEFACKFATCGDGLVPLLLDGLVPRSYYLIKSGQAFTSLMVNFSREVVDMC 609
Query 596 IIMAYVTGGLVQQTSQWLSNLLGTT--------VEKLRPIFEWIEAKLSAGVEFLKDAWE 647
+ MA + V+ ++++ + G + +R I EW + + W
Sbjct 610 MDMALLFMHDVKVATKYVKKVTGKVAVRFKALGIAVVRKITEWFDLAVDTAAS--AAGWL 667
Query 648 ILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIA---GAKLRSLN 704
+ L+ G+F + G I + + + VK F+D ++ ID ++++ G +
Sbjct 668 CYQ-LVNGLFAVANGVITFIQE-VPELVKNFVDKFKTFFKVLIDSMSVSILSGLTVVKTA 725
Query 705 LGEVFIAQSKGLYRQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGEL- 763
V +A SK + K +MP+ E T L G+ V + V + L
Sbjct 726 SNRVCLAGSKVY---EVVQKSLPAYIMPVGC-SEATCLVGEIEPAVFEDDVVDVVKAPLT 781
Query 764 -EALETPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSP---GLLATNNVFRLKGGA 819
+ P SF IV + L + + D+ + G+L F G
Sbjct 782 YQGCCKPPSSFEKICIV------DKLYMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAG-- 833
Query 820 PIKGVTFGED-TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAE 878
K V F + V EV + ++I F LD D VL++ CS + V+ + E VV +
Sbjct 834 --KKVVFNDKPKVKEVPSTRKIKIIFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLD 891
Query 879 AVVKTLQPVSD---LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDD 935
AV TL P + + T + L+ YLFD+ GEE +SRMYCSF PDE+
Sbjct 892 AVESTLSPCKEHGVIGTKVCALLERLVDDYVYLFDEGGEEVIASRMYCSFSAPDEDCVAT 951
Query 936 AECEEEE------IDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQS 989
+E D E+D A +E +E +
Sbjct 952 DVVYADENQDDDADDPVVLVADTQEEDGVAREQVDSADSEICVAHTGGQEMT---EPDVV 1008
Query 990 EIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKE 1026
+ E V + + + A C D +
Sbjct 1009 GSQTPIASAEETEVGEACDREGIAEVKATVCADALDA 1045
Score = 139 bits (350), Expect = 1e-30, Method: Composition-based stats.
Identities = 54/156 (35%), Positives = 79/156 (51%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV D++K + VIVN AN + HG GVAGA+ KA A E+ D +K
Sbjct 1318 CITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKAFINETADMVK 1377
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAG--EDIQLLKAAYENFNSQDILLAPLLS 1128
G VGG +G L KK L++VGP+ E LL+ AY++ N D ++ L+S
Sbjct 1378 AQGVCQVGGCYESTGGKLCKKVLNIVGPDARGHGNECYSLLERAYQHINKCDNVVTTLIS 1437
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + V V + N++ ++ +
Sbjct 1438 AGIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFDVI 1473
Score = 47.4 bits (111), Expect = 0.007, Method: Composition-based stats.
Identities = 50/205 (24%), Positives = 81/205 (40%), Gaps = 23/205 (11%)
Query 1580 DVTKIKPHVNHEGKTFFVLPSDDT-LRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQV 1638
D+ K++ + E +T P+D T AF+ ++ S S H K V
Sbjct 1054 DIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPSDETHFK------V 1107
Query 1639 GGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKT 1698
G S NC+L S L+ +Q L ++F +Q+ + +AG F ++ + K+
Sbjct 1108 CGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKLVKSAPKS 1167
Query 1699 VGEL--GDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNL 1756
+ G V + L S K N C CG L G++AV + G +
Sbjct 1168 IILPQGGYVADFAYFFLSQ---CSFKVHANWRCLKCGM-ELKLQGLDAVFFYGDV----- 1218
Query 1757 KTGVSIPCVCGRDATQYLVQQESSF 1781
VS C CG T L+ + +
Sbjct 1219 ---VSHMCKCGNSMT--LLSADIPY 1238
>sp|P0C6X6|R1AB_CVHOC Replicase polyprotein 1ab OS=Human coronavirus
OC43 OX=31631 GN=rep PE=1 SV=1
Length=7095
Score = 7725 bits (20043), Expect = 0.0, Method: Composition-based stats.
Identities = 2762/5626 (49%), Positives = 3677/5626 (65%), Gaps = 165/5626 (3%)
Query 1528 LSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPH 1587
++ ++K+L + + + TVD N + V + ++G+ G + DG +VTK K
Sbjct 1552 ATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCD 1607
Query 1588 VNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWA 1647
+N++GK FF + + +A D+ L Y + L + KW+ G + K A
Sbjct 1608 INYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYNMLVNCFKWQVVVNGKYFTFKQA 1667
Query 1648 DNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRE 1707
+NNC+++ L LQ L + F QEA+ R+G A F AL+LA G+ D R+
Sbjct 1668 NNNCFVNVSCLMLQSLHLTFKIVQWQEAWLEFRSGRPARFVALVLAKGGFKFGDPADSRD 1727
Query 1708 TMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCG 1767
+ + +L A + CK CG K TG++AVM+ GTLS ++L+ G ++ C CG
Sbjct 1728 FLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGLDAVMHFGTLSREDLEIGYTVDCSCG 1786
Query 1768 RDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDG 1827
+ + V+ + F++ S PA KL +G AN + G+ GHY H+ +++ D
Sbjct 1787 KKLI-HCVRFDVPFLICSNTPASVKLPKGVG-SANIFIGDN-VGHYVHVKCEQSYQLYDA 1843
Query 1828 AHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTE 1886
+++ K+++ G ++D Y K T +Y LD V E +P L YY YYT+
Sbjct 1844 SNVKKVTDVTGKLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQ 1903
Query 1887 QPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDV 1944
+ I T + + NFKL D LN GF + E +T +P GDV
Sbjct 1904 RIIKAQFKTFEKVDGVYTNFKLI--GHTVCDSLNSKLGFDSSKEFVEYKITEWPTATGDV 1961
Query 1945 VAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTS-NSFE 2003
V + Y +++G KP++W ++ + + + +P+ N F+
Sbjct 1962 VLANDDLYVKRYERGCITFGKPVIWLSHEKASLNSLT---------YFNRPLLVDDNKFD 2012
Query 2004 VLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKV 2063
VL V+D + + + E E I+ ++ K +V +VI+ K
Sbjct 2013 VLKVDDVDDSGDSSESGAK----ETKEINIIKLSGVK---KPFKVEDSVIVNDDTSETKY 2065
Query 2064 TQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFL 2123
+ L D+ ++ ++ N LS A+ + TI + V L
Sbjct 2066 VKSLSIVDVYDMWLTGCKYVVRTANALSRAVNVPTIRKFIKFGMTLVSIPIDL-----LN 2120
Query 2124 GQAAITTSNCAKRLAQR--VFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVK 2181
+ N K + + N++ ++F LLF + + T IA K
Sbjct 2121 LREIKPAVNVVKAVRNKTSACFNFIKWLFVLLFGWIKISADN----KVIYTTEIAS---K 2173
Query 2182 SVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSY 2239
KL A N + K+S + A + + + + I F L G P++
Sbjct 2174 LTCKLVALAFKNAFLTFKWSMVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTF 2233
Query 2240 CNGVRELYLNSSNVTT-------------MDFCEGSFPCSICLSGLDSLDSYPALETIQV 2286
+ + N+ ++ T +C GS C CL+G D LD+Y A++ +Q
Sbjct 2234 VGKIAQWIKNTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQY 2293
Query 2287 TISS--YKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLM 2342
+ +L + E +++Y L+T +FY L +Q+ + F+ ++ W
Sbjct 2294 EADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSF 2353
Query 2343 WFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTT 2402
++++ M P +R YI ASF ++ + H+ GC+ S C+ CYKRNR+ RV+C+T
Sbjct 2354 RLLVALANMLPAHVFMRFYIIIASFIKLFSLFKHVAYGCSKSGCLFCYKRNRSLRVKCST 2413
Query 2403 IVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTD 2462
IV GM R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD
Sbjct 2414 IVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTD 2473
Query 2463 QSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDG 2522
+ + V V ++ L++D+ GQ+ Y+ S FV+ NL + K ++V+V +
Sbjct 2474 VAYHTVTDVKQVGCSMRLFYDRDGQRIYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVEN 2533
Query 2523 KSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVP 2582
+ D++ +A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V
Sbjct 2534 DA--DKANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVD 2591
Query 2583 MEKLKALVATAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLE 2641
+ L AL+ATAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE
Sbjct 2592 KKSLNALIATAHSSIKQGTQIYKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLE 2651
Query 2642 VTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQ 2701
+T +SCNN + TY K +N+ DLG I +A+H+ VAK VS IW+V + S
Sbjct 2652 LTDESCNNLVPTYLKSDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQFSSD 2711
Query 2702 LRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAA 2761
+ +++ A K + +LT V+V+TT SLKGG + S + +L+C +
Sbjct 2712 FQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLVCFI-- 2769
Query 2762 LVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG- 2820
+ +MP +T+ D YK + +GV RD+ D CFANK FD W+ G
Sbjct 2770 -GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGL 2828
Query 2821 -SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
Y N +CP+V A+I ++ G V +P VLR LHF+ SA G CYTP
Sbjct 2829 SYYSNSMACPIVVAVIDQDFGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQ 2887
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SI 2938
I YS+F S CVL++ CT+F A G P PYCY L++ + YS L P RY L +
Sbjct 2888 ISYSNFYASGCVLSSACTMFTMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGF 2947
Query 2939 IQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGV 2998
I+FP EG VRVV T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG
Sbjct 2948 IRFPEVLREGLVRVVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGR 3007
Query 2999 DAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAAN 3058
D +LI +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y VV N
Sbjct 3008 DVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSVVFVN 3067
Query 3059 ALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWIT 3118
+++ ++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W
Sbjct 3068 VIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFC 3127
Query 3119 AIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPL 3178
+Y+ + H W F+ +++ + + TFEE AL TF++ K+ Y KL++ L
Sbjct 3128 LLYIAVVVSNHAFWVFSYC--RKLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSD 3183
Query 3179 TQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDF-SNSGADVLYQPPQTSITSA 3237
+NRYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F +N+G+DVLYQPP S++++
Sbjct 3184 VAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTS 3243
Query 3238 VLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDL 3297
LQSG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +L
Sbjct 3244 FLQSGIVKMVNPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNL 3303
Query 3298 LIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLAC 3357
L R ++ F V + L V+ + M+ C+L L V N +TPKY F ++PG+TF+VLA
Sbjct 3304 LCRVTSSDFTVLFDRLSLTVMSYQMRGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAA 3363
Query 3358 YNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 3417
YNG P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD
Sbjct 3364 YNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDF 3423
Query 3418 EGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 3477
G FYGP+ D Q Q D ++N LAWLYAA++N WF+ ++ DFN+ A+
Sbjct 3424 NGDFYGPYKDAQVVQLPIQDYIQSVNFLAWLYAAILNNCNWFIQSDKCSVEDFNVWALSN 3483
Query 3478 NYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVV 3537
+ + D V + L++ TG+++ + AA+K L +NG GR I+GS EDE TP DV
Sbjct 3484 GFSQVKSDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVY 3540
Query 3538 RQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA 3597
+Q +G+ Q K ++ KGT W++ + I+ +W++F +V N T +
Sbjct 3541 QQLAGIKLQSKRTRLFKGTVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MFSITFCALC 3599
Query 3598 IAACAMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRL 3656
+ + AMLLVKHKH +L +++ P L T+ Y N +V ++ + WL S+ Y
Sbjct 3600 VISLAMLLVKHKHLYLTMYITPVLFTLLYNNYLVVYKHTFRGYVYAWLSYYVPSVE-YTY 3658
Query 3657 KDCVMYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVI 3715
D V+Y L++ ++ +T R++ D + + +I++ Y G+ L++ I + ++
Sbjct 3659 TDEVIYGMLLLVGMVFVTLRSINHDLFSFIMFVGRLISVFSLWYKGSNLEEEILL--MLA 3716
Query 3716 SVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
S+ Y+ M +A+ I V L F ++ ++L Y F+GY CY+GLF
Sbjct 3717 SLFGTYTWTTVLSMAVAKVIA-KWVAVNVLYFTDIPQIKIVLLCYLFIGYIISCYWGLFS 3775
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
L+N FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+
Sbjct 3776 LMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQF 3835
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D + AFEK+ LL VL
Sbjct 3836 QSKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFEKLAQLLIVL 3895
Query 3896 LSMQGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
+ AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A +G
Sbjct 3896 FANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARFSGS 3955
Query 3950 S-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQT 4008
+ + LK+L+K+ N+AKS ++RD A+ +KLE+MAD A+T MYK+AR DK++KV SA+QT
Sbjct 3956 ANQQQLKQLEKACNIAKSAYERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQT 4015
Query 4009 MLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTY 4068
MLF+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TY
Sbjct 4016 MLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 4075
Query 4069 ASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVAL 4126
A +W+IQ + D+D QL+EI S + WPL++ A R N SA LQNNEL P L
Sbjct 4076 AGNVWQIQTIQDSDGTNKQLNEI----SDDCNWPLVIIANRYNEVSATVLQNNELMPAKL 4131
Query 4127 RQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTEL 4186
+ +G QT T YYNNS G+ V A+LSD LK+ + K DG + EL
Sbjct 4132 KIQVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LEL 4188
Query 4187 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4246
+PPC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS
Sbjct 4189 DPPCKFTVQDAKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSL 4248
Query 4247 CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4306
CAF+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+Y
Sbjct 4249 CAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIY 4308
Query 4307 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP 4366
CR ++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC +
Sbjct 4309 CRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCRVCGFWRDGSCSCVS-TDT 4366
Query 4367 LMQSADASTFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRF 4425
+QS D + FLNRV G S ARL PC +G STDV RAFDIYN VAG LK NCCRF
Sbjct 4367 TVQSKD-TNFLNRVRGASVDARLVPCASGLSTDVQLRAFDIYNASVAGIGLHLKVNCCRF 4425
Query 4426 QEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISR 4485
Q DE G+ LD +FVVKR ++ Y E Y VKDC VA HDFF F V+G VPHI R
Sbjct 4426 QRVDENGDKLDQFFVVKRTDLTIYNREMKCYERVKDCKFVAEHDFFTFDVEGSRVPHIVR 4485
Query 4486 QRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYA 4545
+ LTKYTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY
Sbjct 4486 KDLTKYTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYK 4545
Query 4546 NLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDS 4605
LG ++L+ +F D + + G+VGVLTLDNQDLNG WYDFGD+V APGCGV I DS
Sbjct 4546 KLGPIFNRALVSATEFADKLVEVGLVGVLTLDNQDLNGKWYDFGDYVIAAPGCGVAIADS 4605
Query 4606 YYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHP 4665
YYS +MP+LT+ AL E +++ +DL++YDFT+ +L LF++YFK+W YHP
Sbjct 4606 YYSYIMPMLTMCHALDCELYVN----NAYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHP 4661
Query 4666 NCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHN 4725
N ++C DDRCI+HCANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N
Sbjct 4662 NTVDCQDDRCIIHCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMN 4721
Query 4726 QDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFN 4785
DV+ H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN
Sbjct 4722 MDVDTHRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFN 4781
Query 4786 KDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVV 4845
+DFYDF +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV
Sbjct 4782 QDFYDFVLSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVV 4841
Query 4846 DKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVI 4905
KYF+ YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+
Sbjct 4842 YKYFEIYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVL 4901
Query 4906 PTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYG 4965
PT+TQMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYG
Sbjct 4902 PTLTQMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYG 4961
Query 4966 GWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLA 5025
GW +ML+ + DV+ P LMGWDYPKCDRAMPN+LRI++SLVLARKH TCC+ S RFYRLA
Sbjct 4962 GWDDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHETCCSQSDRFYRLA 5021
Query 5026 NECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIA 5085
NECAQVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI
Sbjct 5022 NECAQVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIE 5081
Query 5086 DKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLV 5145
D +R LQ RLY +YR+ VD FV E+Y +L KHFSMMILSDD VVCYNS+YA++G +
Sbjct 5082 DLSIRALQKRLYSHVYRSDKVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYI 5141
Query 5146 ASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSR 5205
A+I F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYP+PSR
Sbjct 5142 ANISAFQQVLYYQNNVFMSESKCWVEHDINNGPHEFCSQHTMLVKMDGDDVYLPYPNPSR 5201
Query 5206 ILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELT 5265
ILGAGCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL YI+KL+++L
Sbjct 5202 ILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLAYIKKLYNDLG 5261
Query 5266 GHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPF 5325
+LD YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P
Sbjct 5262 NQILDSYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPL 5321
Query 5326 LCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLC 5385
LCCKCCYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L
Sbjct 5322 LCCKCCYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLV 5381
Query 5386 ANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEET 5445
NG VFGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE
Sbjct 5382 MNGLVFGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEA 5441
Query 5446 FKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGD 5505
FK SY AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K +
Sbjct 5442 FKQSYASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSE 5501
Query 5506 YGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYV--RITGLYPTLNISDEF 5563
+ V YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y R +Y L + F
Sbjct 5502 LTNGVYYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETF 5558
Query 5564 SSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKAL 5623
+NV NYQ +GM++Y T+QGPPGTGKSH AIGLA++Y +AR+VYTA SHAAVDALCEKA
Sbjct 5559 QNNVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVFYCTARVVYTAASHAAVDALCEKAY 5618
Query 5624 KYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNY 5683
K+L I+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY
Sbjct 5619 KFLNINDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNY 5678
Query 5684 DLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCR 5743
+LSV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC
Sbjct 5679 ELSVINARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCY 5738
Query 5744 RCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTR 5803
RCP EIVDTVSALVY+NKLKA + S CFK++YKGV TH+ SSA+N QI ++ +FL
Sbjct 5739 RCPKEIVDTVSALVYENKLKAKNESSLLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKA 5798
Query 5804 NPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN 5863
NP W KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFN
Sbjct 5799 NPLWHKAVFISPYNSQNFAAKRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFN 5858
Query 5864 VAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVA-TLQAENVTGLFKDCSKIITGLHP 5922
VAITRAK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP
Sbjct 5859 VAITRAKKGILCVMSNMQLFEALQFTTLTLDKVPQAVETKVQCSTNLFKDCSKSYSGYHP 5918
Query 5923 TQAPTHLSVDIKFK-TEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEA 5981
AP+ L+VD K+K T L V + +TY RLIS+MGFK++ ++GY +FIT+EEA
Sbjct 5919 AHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLISLMGFKLDVTLDGYCKLFITKEEA 5978
Query 5982 IRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAK 6041
++ VRAW+GFD EG HAT D++GTN PLQLGFSTG++ V TG + F + AK
Sbjct 5979 VKRVRAWVGFDAEGAHATLDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAK 6038
Query 6042 PPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFV 6101
PPG+QFKHLIPLM +G W+VVR +IVQM +D L LSD VV V WA FELT ++YF
Sbjct 6039 APPGEQFKHLIPLMTRGHRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFA 6098
Query 6102 KIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQ 6161
K+G E +C +C KRAT +++ + Y CW HSV DY+YNP ++D+QQWG+ G+L SNHD
Sbjct 6099 KVGREISCNVCTKRATVYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDL 6158
Query 6162 HCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKS 6221
+C VH AHVAS DAIMTRCLAV++CF ++W+VEYPII +EL +N++CR +Q +++K+
Sbjct 6159 YCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVILKA 6218
Query 6222 ALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTD 6281
A+L +++ + +DIGNPK I CV + ++KFYDAQP ++ L YS+ H D F D
Sbjct 6219 AMLCNRYTLCYDIGNPKGIACVK--DFDFKFYDAQPI---VKSVKTLLYSFEAHKDSFKD 6273
Query 6282 GVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNL 6341
G+C+FWNCNVD+YP NA+VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +L
Sbjct 6274 GLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFARAAFEHL 6333
Query 6342 KQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYN 6401
K +PFFYYSD+PC +DYVPLKSATCITRCNLGGAVC HA EYR+YL++YN
Sbjct 6334 KPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLGGAVCLKHAEEYREYLESYN 6393
Query 6402 MMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVY 6461
+AGF+ W+YK FD YNLWNTFT+LQSLENV YN+V GH+ G AGE P +IIN+ V
Sbjct 6394 TATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVV 6453
Query 6462 TKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREA 6521
TK+D DV IF N TT P NVA EL+AKR+++ PE+K+ NL +D+ VIWDY RE+
Sbjct 6454 TKIDKEDVVIFINNTTYPTNVAVELFAKRSVRHHPELKLFRNLNIDVCWKHVIWDYARES 6513
Query 6522 PAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLT 6581
+T GVC TD+ L VLFDGR G + F+ + NGV I+ VK L+
Sbjct 6514 IFCSNTYGVCMYTDL------KFIDKLNVLFDGRDNGAFEAFKRSNNGVYISTTKVKSLS 6567
Query 6582 PSKGPAQASVNGVTL--IGESVKTQFNYFKK----------------------------- 6610
+GP +A +NGV + +G++ + +K
Sbjct 6568 MIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLGVSSNQSPQGNLGSNG 6627
Query 6611 ----VDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVY 6666
V G T FTQSR + F R+ ME DF+ L D FIQ+Y LE YAFEHIVY
Sbjct 6628 KPGNVGGNDALSISTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVY 6687
Query 6667 GDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDL 6726
G+F+ +GGLHL+IGL +R Q S L +++F+ DS++ +YFITD ++G SK VC+VID+
Sbjct 6688 GNFNQKIIGGLHLLIGLYRRQQTSNLVVQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDI 6747
Query 6727 LLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAM 6786
LLDDFV ++KS +L+ +SKVV V +D+ + FMLWC D V TFYP+LQA+ W+PG +M
Sbjct 6748 LLDDFVTLVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYPRLQAASDWKPGYSM 6807
Query 6787 PNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFG 6846
P LYK +E+ L NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H G
Sbjct 6808 PVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLG 6867
Query 6847 AGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDM 6906
AGS+KGVAPG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDM
Sbjct 6868 AGSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDM 6927
Query 6907 YDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWT 6966
YDP TK++ + N SK+GFFTY+C I+ KLALGGS+A+KITE SWNA+LYKLMG+F++WT
Sbjct 6928 YDPITKNIGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWT 6987
Query 6967 AFVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFP 7026
F TN NASSSE FLIG NYL KPK +IDG MHANY+FWRN+ +YSLFDM+KFP
Sbjct 6988 VFCTNANASSSEGFLIGINYLCKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFP 7047
Query 7027 LKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
LKL GTAV++L+ +QINDM+YSLLEKG+L+IR+ N+ V D LVN
Sbjct 7048 LKLAGTAVINLRADQINDMVYSLLEKGKLLIRDTNKEVFVGDSLVN 7093
Score = 295 bits (754), Expect = 1e-77, Method: Composition-based stats.
Identities = 182/970 (19%), Positives = 332/970 (34%), Gaps = 154/970 (16%)
Query 107 LVPHVGETPIAYRNVLLRKNGNKGA-------GGHSYGIDLKSYDLGDELGTDPIEDYEQ 159
+P I + LRK G KGA GG + D K D D++ +P + +
Sbjct 176 FMPVQSRKFIVPWVMYLRKRGEKGAYNKDHGCGGFGHVYDFKVEDAYDQVHDEPKGKFSK 235
Query 160 NWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYP---LDCIKDFLARAGKSMC-TL 215
L R G YVD C G L+ D + K++ T
Sbjct 236 KAYA---------LIRGYRGVKPLLYVDQYGCDYTGSLADGLEAYADKTLQEMKALFPTW 286
Query 216 SEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSAK-----KFDTFKGE 269
S++L + + +AW R + Q+ I S D G
Sbjct 287 SQELPF-------------DVIVAWHVVRDPRYVMRLQSAATICSVAYVANPTEDLCDGS 333
Query 270 C----PKFVFPLNSKVKVIQPRVEKKKTEGFMGR--IRSVYPVASPQECNNMHLSTLMKC 323
P V+ +S + + + + Y VA ++C + + C
Sbjct 334 VVIKEPVHVYADDSIILRQYNLFDIMSHFYMEADTVVNAFYGVA-LKDCGFVMQFGYIDC 392
Query 324 --NHCDEVSWQTCDFLKATCE-HCGTENLVIEG-PTTCGYLPTNAVVKMPCPACQDPEIG 379
+ CD W + + CG V + + G LP N V+
Sbjct 393 EQDSCDFKGWIPGNMIDGFACTTCGHVYEVGDLIAQSSGVLPVNPVLHT----------- 441
Query 380 PEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADIGS----GH 435
S A Y ++ G FGGCV+ R W+P + + S +
Sbjct 442 --KSAAGYGGFGCKDSFTLYGQTVVYFGGCVY----WSPARNIWIPILKSSVKSYDSLVY 495
Query 436 TGITGDNVETLNEDLL---EILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIK 492
TG+ G +L+ L + + L + + + ++
Sbjct 496 TGVLGCKAIVKETNLICKALYLDYVQHKCGNLHQRELLGVSDVWHKQLLINRGVYKPLLE 555
Query 493 SLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTL 552
++DY + + S + V + + R+ + G QA
Sbjct 556 NIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSG---QAFC---------- 602
Query 553 DAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQW 612
D A+ + + +LD +D++ L + ++ +A Q
Sbjct 603 DYADKLCHAVVSKSKELLD-------VSLDSLGAAIHYLNSKIVDLA-----------QH 644
Query 613 LSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIK 672
S+ + V K+ F+ L AW + L G + +V+ I NI
Sbjct 645 FSDFGTSFVSKIVHFFKTF-----TTSTALAFAWVLFHVL-HGAYIVVESDIYFV-KNIP 697
Query 673 DCVKCFIDVVNKALEMCIDQVT---IAGAKLRSLNLGEVFIAQSK------GLYRQCIRG 723
++ +D + I G + + ++ K GL
Sbjct 698 RYASAVAQAFQSVAKVVLDSLRVTFIDGLSCFKIGRRRICLSGRKIYEVERGLLHSSQLP 757
Query 724 KEQLQLLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
+ L MP KA ++ +L+G D L V + L ++ V
Sbjct 758 LDVYDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPC-----GYSEPPKVA 812
Query 781 TPVCV-NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY- 837
+C+ + + + + DK + + + +R+ + VTF E TV E+
Sbjct 813 DKICIVDNVYMAKAGDKYYPVVVDDHVGLLDQAWRVPCAG--RRVTFKEQPTVKEIISMP 870
Query 838 KNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDL---LTNM 894
K +++ +ELD + +LN C V+ V+ ++ EF VV +A+ + L P +L +
Sbjct 871 KIIKVFYELDNDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKV 930
Query 895 GIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTE 954
L + +LFD+AGEE F+ ++YC+F P+++ + ++E+ E E
Sbjct 931 SAFLQKLEDNPLFLFDEAGEEVFAPKLYCAFTAPEDD---------DFLEESDVEEDDVE 981
Query 955 DDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKL-- 1012
+ L + A V E+EE + L+DT + + EE V + + ++ L
Sbjct 982 GEETDLTIT-SAGQPCVASEQEESSEVLEDTLDDGPSVETSDSQVEEDV-EMSDFVDLES 1039
Query 1013 ----TDNVAI 1018
+NV
Sbjct 1040 VIQDYENVCF 1049
Score = 174 bits (441), Expect = 4e-41, Method: Composition-based stats.
Identities = 51/156 (33%), Positives = 81/156 (52%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ + +K
Sbjct 1272 CITPNVCFVKGDIIKVSKLVKAEVVVNPANGHMVHGGGVAKAIAVAAGQQFVKETTNMVK 1331
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDILLAPLLS 1128
G G + +G L K L+VVGP+ + LL+ Y++FN+ D ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYVLLERVYKHFNNYDCVVTTLIS 1391
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + T + QV + N++ ++ +
Sbjct 1392 AGIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLI 1427
Score = 48.5 bits (114), Expect = 0.003, Method: Composition-based stats.
Identities = 37/150 (25%), Positives = 61/150 (41%), Gaps = 16/150 (11%)
Query 1634 KFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILA 1693
+F +V GL K NNC+L SVL +Q+L +F LQ+ + + + F ++
Sbjct 1057 EFVKVLGLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1694 Y--SNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTL 1751
+N + + G V + L L + V C C L G++A+ + G +
Sbjct 1117 KIPANIVLPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1752 SYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
VS C CG L+ + F
Sbjct 1173 --------VSHICKCGESMV--LIDVDVPF 1192
>sp|P0C6W9|R1AB_CVBM Replicase polyprotein 1ab OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=rep PE=3 SV=1
Length=7094
Score = 7720 bits (20031), Expect = 0.0, Method: Composition-based stats.
Identities = 2756/5625 (49%), Positives = 3676/5625 (65%), Gaps = 164/5625 (3%)
Query 1528 LSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPH 1587
++ ++K+L + + + TVD N + V + ++G+ G + DG +VTK K
Sbjct 1552 ATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCD 1607
Query 1588 VNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWA 1647
+N++GK FF + + +A D+ L Y + L + KW+ G + K A
Sbjct 1608 INYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQA 1667
Query 1648 DNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRE 1707
+NNC+++ L LQ L +KF QEA+ R+G A F +L+LA G+ D R+
Sbjct 1668 NNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRD 1727
Query 1708 TMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCG 1767
+ + +L A + CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG
Sbjct 1728 FLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCG 1786
Query 1768 RDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDG 1827
+ + V+ + F++ S PA KL +G AN + G+ + GHY H+ +++ D
Sbjct 1787 KKLI-HCVRFDVPFLICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDA 1843
Query 1828 AHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTE 1886
+++ K+++ G ++D Y K T +Y LD V E +P L YY YYT+
Sbjct 1844 SNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQ 1903
Query 1887 QPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDV 1944
+ I T + + NFKL D LN GF + E VT +P GDV
Sbjct 1904 RIIKAQFKTFEKVDGVYTNFKLI--GHTVCDILNAKLGFDSSKEFVEYKVTEWPTATGDV 1961
Query 1945 VAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFE 2003
V Y +++G KP++W ++ + + + +P+ N F+
Sbjct 1962 VLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFD 2012
Query 2004 VLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKV 2063
VL V+D +++ + E E I+ ++ K +V +VI+ +K
Sbjct 2013 VLKVDDVDDGGDISESDAK----EPKEINIIKLSGVK---KPFKVEDSVIVNDDTSEIKY 2065
Query 2064 TQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFL 2123
+ L D+ ++ ++ N LS A+ + TI + V L
Sbjct 2066 VKSLSIVDVYDMWLTGCRCVVRTANALSRAVNVPTIRKFIKFGMTLVSIPIDL-----LN 2120
Query 2124 GQAAITTSNCAKRLAQRV--FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVK 2181
+ N K + ++ N++ ++F LLF + + T +A K
Sbjct 2121 LREIKPVFNVVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---K 2173
Query 2182 SVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSY 2239
KL A N + K+S + A + + + + I F L G P++
Sbjct 2174 LTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTF 2233
Query 2240 CNGVRELYLNSSNVTT-------------MDFCEGSFPCSICLSGLDSLDSYPALETIQV 2286
+ + N+ ++ T +C GS C CL+G D LD+Y A++ +Q
Sbjct 2234 VGKIAQWIKNTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQY 2293
Query 2287 TISS--YKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLM 2342
+ +L + E +++Y L+T +FY L +Q+ + F+ ++ W +
Sbjct 2294 EADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSV 2353
Query 2343 WFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTT 2402
++S+ M P +R YI ASF ++ + H+ GC+ S C+ CYKRNR+ RV+C+T
Sbjct 2354 RLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCST 2413
Query 2403 IVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTD 2462
IV GM R + ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD
Sbjct 2414 IVGGMIRYYDAMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTD 2473
Query 2463 QSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDG 2522
+ + V V + L++D+ GQ+TY+ S FV+ NL + K ++V+V +
Sbjct 2474 VAYHTVTDVKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVEN 2533
Query 2523 KSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVP 2582
+ D++ +A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V
Sbjct 2534 DA--DKANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVD 2591
Query 2583 MEKLKALVATAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLE 2641
+ L AL+ATAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE
Sbjct 2592 KKSLNALIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLE 2651
Query 2642 VTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQ 2701
+T +SCNN + TY K +N+ DLG I +A+H+ VAK VS IW+V + LS
Sbjct 2652 LTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSD 2711
Query 2702 LRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAA 2761
+ +++ A K + +LT V+V+TT SLKGG + S + +L+C +
Sbjct 2712 FQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLVCFI-- 2769
Query 2762 LVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG- 2820
+ +MP +T+ D YK + +GV RD+ D CFANK FD W+ G
Sbjct 2770 -GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGL 2828
Query 2821 -SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
Y N +CP+V A++ ++ G V +P VLR LHF+ SA G CYTP
Sbjct 2829 SYYSNSMACPIVVAVVDQDFGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQ 2887
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SI 2938
I YS+F S CVL++ CT+F A G P PYCY L++ + YS L P RY L +
Sbjct 2888 ISYSNFYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGF 2947
Query 2939 IQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGV 2998
I+FP EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG
Sbjct 2948 IRFPEVLREGLVRIVRTRSMPYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGR 3007
Query 2999 DAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAAN 3058
D +LI +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N
Sbjct 3008 DVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVN 3067
Query 3059 ALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWIT 3118
+++ ++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W
Sbjct 3068 VIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFC 3127
Query 3119 AIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPL 3178
+Y+ + H W F+ +++ + + TFEE AL TF++ K+ Y KL++ L
Sbjct 3128 LLYISVVVSNHAFWVFSYC--RQLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSD 3183
Query 3179 TQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDF-SNSGADVLYQPPQTSITSA 3237
+NRYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F +N+G+DVLYQPP S++++
Sbjct 3184 VAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTS 3243
Query 3238 VLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDL 3297
LQSG KM P+ KVE C+V VT G TLNGLWL D VYCPRHVIC+A DM NP+Y +L
Sbjct 3244 FLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDYTNL 3303
Query 3298 LIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLAC 3357
L R ++ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA
Sbjct 3304 LCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAA 3363
Query 3358 YNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 3417
YNG P G + MR ++TIKGSFL GSCGSV + I DCV F YMH +EL TG H GTD
Sbjct 3364 YNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMGDCVKFVYMHQLELSTGCHTGTDF 3423
Query 3418 EGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 3477
G FYGP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+
Sbjct 3424 NGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSN 3483
Query 3478 NYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVV 3537
+ + D V + L++ TG+++ + AA+K L +NG GR I+GS EDE TP DV
Sbjct 3484 GFSQVKSDLV--IDALASMTGVSLETLLAAIKHL-KNGFQGRQIMGSCSFEDELTPSDVY 3540
Query 3538 RQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA 3597
+Q +G+ Q K ++VKG W++ + I+ +W++F +V N L T +
Sbjct 3541 QQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALC 3599
Query 3598 IAACAMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRL 3656
+ + MLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y
Sbjct 3600 VISLTMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTY 3658
Query 3657 KDCVMYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVI 3715
D V+Y L++ ++ +T R++ + + VI++V Y G+ L++ I + ++
Sbjct 3659 TDEVIYGMLLLIGMVFVTLRSINQYLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLA 3716
Query 3716 SVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
S+ Y+ M A+ I V L F ++ +++ Y F+GY CY+GLF
Sbjct 3717 SLFGTYTWTTALSMAAAKVIA-KWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFS 3775
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
L+N FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+
Sbjct 3776 LMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQF 3835
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL
Sbjct 3836 QSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVL 3895
Query 3896 LSMQGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
+ AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G
Sbjct 3896 FANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGS 3955
Query 3950 S-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQT 4008
+ + LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QT
Sbjct 3956 ANQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQT 4015
Query 4009 MLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTY 4068
MLF+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TY
Sbjct 4016 MLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 4075
Query 4069 ASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVAL 4126
A +W+IQ + D+D QL EI S + WPL++ A R N SA LQNNEL P L
Sbjct 4076 AGNVWQIQTIQDSDGTNKQLHEI----SDDCNWPLVIIANRHNEVSATALQNNELMPAKL 4131
Query 4127 RQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTEL 4186
+ +G QT T YYNNS G+ V A+LSD LK+ + K DG + EL
Sbjct 4132 KTQVVNSGPDQTCNTPTQ--CYYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LEL 4188
Query 4187 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4246
+PPC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS
Sbjct 4189 DPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSL 4248
Query 4247 CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4306
CAF+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+Y
Sbjct 4249 CAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIY 4308
Query 4307 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP 4366
CR ++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC +
Sbjct 4309 CRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDT 4366
Query 4367 LMQSADASTFLNRVCGVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRF 4425
+QS D + FLNRV G S ARL PC +G STDV RAFDI N VAG LK NCCRF
Sbjct 4367 TVQSKD-TNFLNRVRGTSVDARLVPCASGLSTDVQLRAFDICNASVAGIGLHLKVNCCRF 4425
Query 4426 QEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISR 4485
Q DE G+ LD +FVVKR ++ Y E Y VKDC VA HDFF F V+G VPHI R
Sbjct 4426 QRVDENGDKLDQFFVVKRTDLTIYNREMECYERVKDCKFVAEHDFFTFDVEGSRVPHIVR 4485
Query 4486 QRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYA 4545
+ LTKYTM DL YALRHFD +C L +IL Y C+ YF KKDWYDFVENPDI+ VY
Sbjct 4486 KDLTKYTMLDLCYALRHFDRNDCMLLCDILSIYAGCEQSYFTKKDWYDFVENPDIINVYK 4545
Query 4546 NLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDS 4605
LG ++L+ +F D + + G+VG+LTLDNQDLNG WYDFGD+V APGCGV I DS
Sbjct 4546 KLGPIFNRALVSATEFADKLVEVGLVGILTLDNQDLNGKWYDFGDYVIAAPGCGVAIADS 4605
Query 4606 YYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHP 4665
YYS +MP+LT+ AL E +++ +DL++YDFT+ +L LF++YFK+W YHP
Sbjct 4606 YYSYMMPMLTMCHALDCELYVN----NAYRLFDLVQYDFTDYKLELFNKYFKHWSMPYHP 4661
Query 4666 NCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHN 4725
N ++C DDRCI+ CANFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELG+V N
Sbjct 4662 NTVDCQDDRCIIRCANFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGIVMN 4721
Query 4726 QDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFN 4785
DV+ H RLS K+LL+YAADPA+H AS + L D RT CFSVAA+T+ V FQTVKPGNFN
Sbjct 4722 MDVDTHRYRLSLKDLLLYAADPALHVASASALYDLRTCCFSVAAITSGVKFQTVKPGNFN 4781
Query 4786 KDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVV 4845
+DFYDF +SKG KEGSSV+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV
Sbjct 4782 QDFYDFILSKGLLKEGSSVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVV 4841
Query 4846 DKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVI 4905
KYF+ YDGGCI A+QVIVNN DKSAG+PFNK+GKARLYY+++S+E+QD ++AYTKRNV+
Sbjct 4842 YKYFEIYDGGCIPASQVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQDEIYAYTKRNVL 4901
Query 4906 PTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYG 4965
PT+TQMNLKYAISAKNRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYG
Sbjct 4902 PTLTQMNLKYAISAKNRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYG 4961
Query 4966 GWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLA 5025
GW +ML+ + DV+ P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ S RFYRLA
Sbjct 4962 GWDDMLRRLIKDVDNPVLMGWDYPKCDRAMPNILRIVSSLVLARKHEACCSQSDRFYRLA 5021
Query 5026 NECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIA 5085
NE AQVLSE+VMCGG YVKPGGTSSGDATTA+ANSVFNICQAV+ANV AL+S +GNKI
Sbjct 5022 NEYAQVLSEIVMCGGCYYVKPGGTSSGDATTAFANSVFNICQAVSANVCALMSCNGNKIE 5081
Query 5086 DKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLV 5145
D +R LQ RLY +YR+ VD FV E+Y +L KHFSMMILSDD VVCYNS+YA++G +
Sbjct 5082 DLSIRALQKRLYSHVYRSDMVDSTFVTEYYEFLNKHFSMMILSDDGVVCYNSDYASKGYI 5141
Query 5146 ASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSR 5205
A+I F+ VLYYQNNVFMSE+KCW E D+ GPHEFCSQHTMLVK D VYLPYPDPSR
Sbjct 5142 ANISAFQQVLYYQNNVFMSESKCWVENDINNGPHEFCSQHTMLVKMDGDDVYLPYPDPSR 5201
Query 5206 ILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELT 5265
ILGAGCFVDD++KTD L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL++EL
Sbjct 5202 ILGAGCFVDDLLKTDSVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNELG 5261
Query 5266 GHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPF 5325
+LD YSV+L+ + ++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P
Sbjct 5262 NQILDSYSVILSTCDGQKFTDESFYKNMYLRSAVMQSVGACVVCSSQTSLRCGSCIRKPL 5321
Query 5326 LCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLC 5385
LCCKCCYDHV++T HK VLSV+PYVCNAPGCDV DVT+LYLGGMSYYC+ HKP SF L
Sbjct 5322 LCCKCCYDHVMATDHKYVLSVSPYVCNAPGCDVNDVTKLYLGGMSYYCEDHKPQYSFKLV 5381
Query 5386 ANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEET 5445
NG VFGLYK +C GS + DFN IA+C WT+ DYILAN CTERLKLFAAET KATEE
Sbjct 5382 MNGMVFGLYKQSCTGSPYIDDFNRIASCKWTDVDDYILANECTERLKLFAAETQKATEEA 5441
Query 5446 FKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGD 5505
FK SY AT++E++S+REL LSWE+GK +PPLN+NYVFTGY TKN K +GEY F+K +
Sbjct 5442 FKQSYASATIQEIVSERELILSWEIGKVKPPLNKNYVFTGYHFTKNGKTVLGEYVFDKSE 5501
Query 5506 YGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYV--RITGLYPTLNISDEF 5563
+ V YR TTTYKL+VGD FVLTSH+V LSAPTLVPQE+Y R +Y L + F
Sbjct 5502 LTNGVYYRATTTYKLSVGDVFVLTSHSVANLSAPTLVPQENYSSIRFASVYSVL---ETF 5558
Query 5564 SSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKAL 5623
+NV NYQ +GM++Y T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA
Sbjct 5559 QNNVVNYQHIGMKRYCTVQGPPGTGKSHLAIGLAVYYCTARVVYTAASHAAVDALCEKAY 5618
Query 5624 KYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNY 5683
K+L I+ C+RI+PA+ RVEC+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY
Sbjct 5619 KFLNINDCTRIVPAKVRVECYDKFKINDTTRKYVFTTINALPEMVTDIVVVDEVSMLTNY 5678
Query 5684 DLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCR 5743
+LSV+NAR+RAKHYVYIGDPAQLPAPR LL+KGTLEP+YFN+V +LM +GPD+FLGTC
Sbjct 5679 ELSVINARIRAKHYVYIGDPAQLPAPRVLLSKGTLEPKYFNTVTKLMCCLGPDIFLGTCY 5738
Query 5744 RCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTR 5803
RCP EIVDTVSALVY+NKLKA + S+ CFK++YKGV TH+ SSA+N QI ++ +FL
Sbjct 5739 RCPKEIVDTVSALVYENKLKAKNESSSLCFKVYYKGVTTHESSSAVNMQQIYLINKFLKA 5798
Query 5804 NPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN 5863
NP W KAVFISPYNSQN A ++LGL TQTVDS+QGSEYDYVI++QT ETAHS NVNRFN
Sbjct 5799 NPLWHKAVFISPYNSQNFAARRVLGLQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFN 5858
Query 5864 VAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVA-TLQAENVTGLFKDCSKIITGLHP 5922
VAITRAK GILC+MS+ L++ LQFT+L + + A + + T LFKDCSK +G HP
Sbjct 5859 VAITRAKKGILCVMSNMQLFEALQFTTLTVDKVPQAVETRVQCSTNLFKDCSKSYSGYHP 5918
Query 5923 TQAPTHLSVDIKFK-TEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEA 5981
AP+ L+VD K+K T L V + +TY RL S+MGFK++ ++GY +FIT+EEA
Sbjct 5919 AHAPSFLAVDDKYKATGDLAVCLGIGDSAVTYSRLTSLMGFKLDVTLDGYCKLFITKEEA 5978
Query 5982 IRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAK 6041
++ VRAW+GFD EG HATRD++GTN PLQLGFSTG++ V TG + F + AK
Sbjct 5979 VKRVRAWVGFDAEGAHATRDSIGTNFPLQLGFSTGIDFVVEATGLFADRDGYSFKKAVAK 6038
Query 6042 PPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFV 6101
PPG+QFKHLIPLM +G W+VVR +IVQM +D L LSD VV V WA FELT ++YF
Sbjct 6039 APPGEQFKHLIPLMTRGQRWDVVRPRIVQMFADHLIDLSDCVVLVTWAANFELTCLRYFA 6098
Query 6102 KIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQ 6161
K+G E +C +C KRAT +++ + Y CW HSV DY+YNP ++D+QQWG+ G+L SNHD
Sbjct 6099 KVGREISCNVCTKRATAYNSRTGYYGCWRHSVTCDYLYNPLIVDIQQWGYIGSLSSNHDL 6158
Query 6162 HCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKS 6221
+C VH AHVAS DAIMTRCLAV++CF ++W+VEYPII +EL +N++CR +Q +++K+
Sbjct 6159 YCSVHKGAHVASSDAIMTRCLAVYDCFCNNINWNVEYPIISNELSINTSCRVLQRVMLKA 6218
Query 6222 ALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTD 6281
A+L +++ + +DIGNPKAI CV + ++KFYDAQP ++ L Y + H D F D
Sbjct 6219 AMLCNRYTLCYDIGNPKAIACVK--DFDFKFYDAQPI---VKSVKTLLYFFEAHKDSFKD 6273
Query 6282 GVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNL 6341
G+C+FWNCNVD+YP NA+VCRFDTRVL+NLNLPGC+GGSLYVNKHAFHT F ++AF +L
Sbjct 6274 GLCMFWNCNVDKYPPNAVVCRFDTRVLNNLNLPGCNGGSLYVNKHAFHTKPFSRAAFEHL 6333
Query 6342 KQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYN 6401
K +PFFYYSD+PC +DYVPLKSATCITRCNL GAVC HA EYR+YL++YN
Sbjct 6334 KPMPFFYYSDTPCVYMDGMDAKQVDYVPLKSATCITRCNLVGAVCLKHAEEYREYLNSYN 6393
Query 6402 MMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVY 6461
+AGF+ W+YK FD YNLWNTFT+LQSLENV YN+V GH+ G AGE P +IIN+ V
Sbjct 6394 TATTAGFTFWVYKTFDFYNLWNTFTKLQSLENVVYNLVKTGHYTGQAGEMPCAIINDKVV 6453
Query 6462 TKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREA 6521
K+D DV IF N TT P NVA EL+AKR+I+ PE+K+ NL +D+ VIWDY RE+
Sbjct 6454 AKIDKEDVVIFINNTTYPTNVAVELFAKRSIRHHPELKLFRNLNIDVCWKHVIWDYARES 6513
Query 6522 PAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLT 6581
+T GVC TD+ L VLFDGR G ++ F+ + NGV I+ VK L+
Sbjct 6514 IFCSNTYGVCMYTDL------KFIDKLNVLFDGRDNGALEAFKRSNNGVYISTTKVKSLS 6567
Query 6582 PSKGPAQASVNGVTL--IGESVKTQFNYFKK----------------------------- 6610
+GP +A +NGV + +G++ + +K
Sbjct 6568 MIRGPPRAELNGVVVDKVGDTDCVFYFAVRKEGQDVIFSQFDSLRVSSNQSPQGNLGSNE 6627
Query 6611 ---VDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYG 6667
V G T FTQSR + F R+ ME DF+ L D FIQ+Y LE YAFEHIVYG
Sbjct 6628 PGNVGGNDALATSTIFTQSRVISSFTCRTDMEKDFIALDQDVFIQKYGLEDYAFEHIVYG 6687
Query 6668 DFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLL 6727
+F+ +GGLHL+IGL +R Q S L +++F+ DS++ +YFITD ++G SK VC+VID+L
Sbjct 6688 NFNQKIIGGLHLLIGLYRRQQTSNLVIQEFVSYDSSIHSYFITDEKSGGSKSVCTVIDIL 6747
Query 6728 LDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMP 6787
LDDFV ++KS +L+ +SKVV V +D+ + FMLWC D V TFY +LQA+ W+PG +MP
Sbjct 6748 LDDFVALVKSLNLNCVSKVVNVNVDFKDFQFMLWCNDEKVMTFYLRLQAASDWKPGYSMP 6807
Query 6788 NLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGA 6847
LYK +E+ L NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GA
Sbjct 6808 VLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGA 6867
Query 6848 GSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY 6907
GS+KGVAPG+AVLRQWLP GT+LVD+DL FVSD+ +T GDC T+ +WDLIISDMY
Sbjct 6868 GSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPFDCQWDLIISDMY 6927
Query 6908 DPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTA 6967
DP TK++ + N SK+GFFTY+C I+ KLALGGS+A+KITE SWNA+LYKLMG+F++WT
Sbjct 6928 DPITKNIGEYNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSWNAELYKLMGYFAFWTV 6987
Query 6968 FVTNVNASSSEAFLIGANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPL 7027
F TN NASSSE FLIG NYLGKPK +IDG MHANY+FWRN+ +YSLFDM+KFPL
Sbjct 6988 FCTNANASSSEGFLIGINYLGKPKVEIDGNVMHANYLFWRNSTVWNGGAYSLFDMAKFPL 7047
Query 7028 KLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
KL GTAV++L+ +QINDM+YSLLEKG+L++R+ N+ V D +VN
Sbjct 7048 KLAGTAVINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDSMVN 7092
Score = 301 bits (770), Expect = 2e-79, Method: Composition-based stats.
Identities = 182/970 (19%), Positives = 327/970 (34%), Gaps = 154/970 (16%)
Query 107 LVPHVGETPIAYRNVLLRKNGNKGA-------GGHSYGIDLKSYDLGDELGTDPIEDYEQ 159
+P I + LRK G KGA GG + + K D D + +P + +
Sbjct 176 FMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSK 235
Query 160 NWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYP---LDCIKDFLARAGKSMCTLS 216
L R G YVD C G L+ D + K++ +
Sbjct 236 KAYA---------LIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIW 286
Query 217 EQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSAK-----KFDTFKGEC 270
Q + +AW R + Q+ I+S D G
Sbjct 287 SQELPFD------------VTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSV 334
Query 271 ----PKFVFPLNSKVKVIQPRVEKKKTEGFMGR--IRSVYPVASPQECNNMHLSTLMKC- 323
P V+ +S + V+ + + Y V ++C + + C
Sbjct 335 VIKEPVHVYADDSIILRQHNLVDIMSCFYMEADAVVNAFYGVD-LKDCGFVMQFGYIDCE 393
Query 324 -NHCDEVSWQTCDFLKATCE-HCGTENLVIEGP-TTCGYLPTNAVVKMPCPACQDPEIGP 380
+ CD W + + CG + + G LP N V+
Sbjct 394 QDLCDFKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHT------------ 441
Query 381 EHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADI----GSGHT 436
S A Y ++ G FGGCV+ R W+P + + G +T
Sbjct 442 -KSAAGYGGFGCKDSFTLYGQTVVYFGGCVY----WSPARNIWIPILKSSVKSYDGLVYT 496
Query 437 GITGDNVETLNEDLL---EILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKS 493
G+ G +L+ L + + L + + + +++
Sbjct 497 GVVGCKAIVKETNLICKALYLDYVQHKCGNLHQRELLGVSDVWHKQLLLNRGVYKPLLEN 556
Query 494 LDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLD 553
+DY + + S + V + + R+ + G QA D
Sbjct 557 IDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSG---QAFC----------D 603
Query 554 AANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQWL 613
A + + +LD +D++ L + ++ +A Q
Sbjct 604 YAGKICHAVVSKSKELLD-------VSLDSLGAAIHYLNSKIVDLA-----------QHF 645
Query 614 SNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
S+ + V K+ F+ L AW + L G + +V+ I NI
Sbjct 646 SDFGTSFVSKIVHFFKTF-----TTSTALAFAWVLFHVL-HGAYIVVESDIYFV-KNIPR 698
Query 674 CVKCFIDVVNKALEMCIDQVT---IAGAKLRSLNLGEVFIAQSK------GLYRQCIRGK 724
++ +D + I G + + ++ SK GL
Sbjct 699 YASAVAQAFRSVAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERGLLHSSQLPL 758
Query 725 EQLQLLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGT 781
+ L MP K ++ +L+G D L V + L ++ V
Sbjct 759 DVYDLTMPSQVQKTKQKPIYLKGSGSDFSLADSVVEVVTTSLTPC-----GYSEPPKVAD 813
Query 782 PVCV-NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-K 838
+C+ + + + + DK + + + +R+ + VTF E TV E+ K
Sbjct 814 KICIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAG--RCVTFKEQPTVNEIASTPK 871
Query 839 NVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDL---LTNMG 895
+++ +ELD+ + +LN C V+ V+ ++ EF VV +A+ + L P +L +
Sbjct 872 TIKVFYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVS 931
Query 896 IDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTED 955
L + + +LFD+AGEE + ++YC+F P EDD EE ++E T+
Sbjct 932 AFLQKLEDNSLFLFDEAGEEVLAPKLYCAFTAP----EDDDFLEESGVEEDDVEGEETD- 986
Query 956 DYQGLPLEFGASAE-TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKL-- 1012
L ++ E V E+EE + L+DT + + EE V Q + ++ L
Sbjct 987 ------LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDV-QMSDFVDLES 1039
Query 1013 ----TDNVAI 1018
+NV
Sbjct 1040 VIQDYENVCF 1049
Score = 176 bits (446), Expect = 1e-41, Method: Composition-based stats.
Identities = 51/156 (33%), Positives = 79/156 (51%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDILLAPLLS 1128
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + T + QV + N++ ++ +
Sbjct 1392 AGIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLI 1427
Score = 47.4 bits (111), Expect = 0.007, Method: Composition-based stats.
Identities = 37/150 (25%), Positives = 60/150 (40%), Gaps = 16/150 (11%)
Query 1634 KFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILA 1693
+F +V L K NNC+L SVL +Q+L +F LQ+ + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1694 Y--SNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTL 1751
+N V + G V + L L + V C C L G++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1752 SYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
VS C CG L+ + F
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPF 1192
>sp|P0C6X3|R1AB_CVHN2 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=rep PE=3 SV=1
Length=7152
Score = 7665 bits (19889), Expect = 0.0, Method: Composition-based stats.
Identities = 2715/5671 (48%), Positives = 3652/5671 (64%), Gaps = 167/5671 (3%)
Query 1488 RDWSYSGQ----RTELGVEFLKRGDKIVYHTLESPVEFHLDGEV--LSLDKLKSLLSLRE 1541
+DW + V++ + + I + + DG +++++ LL
Sbjct 1563 KDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLL---- 1618
Query 1542 VKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSD 1601
K I V TVD N + + + +G+ G + DG DVTK+K + K + +
Sbjct 1619 AKKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENL 1678
Query 1602 DTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
A + D+ L Y + L KW G S + + NNCY++ L LQ
Sbjct 1679 SLADISAVQSSFGFDQQQLLAYYNFL-TVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQ 1737
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
+ +KFN QEA+Y RAG AL+LA + E D + + +L+ A+L A
Sbjct 1738 HINLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGA 1797
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
L ++C CG K + GV+AVM+ GTL+ +L G I C C + + F
Sbjct 1798 ICELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAG-RIVHCTKLNVPF 1855
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S P L + AN + G GHYTH+ D + K + G +T
Sbjct 1856 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1913
Query 1842 DVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLPN 1899
D Y K + T T +Y LD V P L YY + YYT+ I +
Sbjct 1914 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYTKPIIKAQFKPFAKVD 1973
Query 1900 ASFDNFKLTCSNTKFADDLNQMTGFTKP-ASRELSVTFFPDLNGDVVAIDYRHYSASFKK 1958
+ NFKL + LN GF E VT +P GDVV Y + K
Sbjct 1974 GVYTNFKLVGHD--ICAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2031
Query 1959 GAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKP-VDTSNSFEVLAVEDTQGMDNLA 2017
G + KP++W + + + + KP + N + VL+V+ +
Sbjct 2032 GCETFGKPVIWLCHDEASLNSLT---------YFNKPSFKSENRYSVLSVDSV------S 2076
Query 2018 CESQQPTSEEVVENPTIQKEV-IECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAY 2076
ESQ V+E+ KEV ++ KT ++ +I+ + +KV + L D+ Y
Sbjct 2077 EESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDMY 2136
Query 2077 VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKR 2136
+ + NELS + T+ + I + L ++ Q + R
Sbjct 2137 LTGCDYVVWVANELSRLVKSPTVREYIRYGIKPITIPIDLLCLRD-DNQTLLVPKIFKAR 2195
Query 2137 LAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVK 2196
+ F ++ ++F +F L FT T IA ++ L L +
Sbjct 2196 AIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAFQTFR 2249
Query 2197 SPKFSKLFTIAMWLLLLSICLGSLICVTAAFG----------------VLLSNFGAPSYC 2240
F K F + + L + + + F + + FG + C
Sbjct 2250 WSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTIC 2309
Query 2241 NGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL--DLTIL 2298
+ +L + T FC GSF C +C SG D LD+Y A++ +Q + L ++++
Sbjct 2310 DFYSKLGVG----FTSHFCNGSFICELCYSGFDMLDTYAAIDFVQYEVDRRVLFDYVSLV 2365
Query 2299 GLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSA 2356
L E V+ Y L+T +FY L +Q+F + F+ + WL+ FI+ + M P
Sbjct 2366 KLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAFV 2425
Query 2357 MVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYAN 2416
++R YI + Y + HI+ GC + C+ CYKRN + RV+C+TIV G+ R + + AN
Sbjct 2426 LLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITAN 2485
Query 2417 GGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNG 2476
GG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2486 GGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVGC 2545
Query 2477 ALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASV 2536
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + + D + +A V
Sbjct 2546 MMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDA--DRANFLNAVV 2603
Query 2537 YYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSE 2596
+Y+Q + +PILL+D+ L++ + V+ MFD YVDTF + F V + V AH+
Sbjct 2604 FYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVNIAHAS 2663
Query 2597 LAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYN 2655
L +GV L+ VL TFV R+ +D+DV+T+ + + + + + LE T ++ NN + TY
Sbjct 2664 LREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVPTYL 2723
Query 2656 KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNI 2715
K +N+ DLG I A+H+ VAK+ N+S IW + + L+ L+ +++ A K +
Sbjct 2724 KSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDTFNQLTADLQHKLKKACVKTGL 2783
Query 2716 PFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSI 2775
+LT V ++TT SLKGG ++S ++ +L+C + + + ++P +++
Sbjct 2784 KLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPTYSVYK 2840
Query 2776 HDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAA 2833
D + +K I +GV RDI D CFANK FD W+ G Y N CP+V A
Sbjct 2841 SDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSFYYHNSMDCPIVVA 2900
Query 2834 IITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLA 2893
++ +IG + +P VLR LHFL F++ CYTP I Y+DF S CVL+
Sbjct 2901 VMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVLS 2959
Query 2894 AECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRV 2952
+ CT+FK G P PYCY +++ + Y+ L P TRY L + + I+FP+ EG VR+
Sbjct 2960 SLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVRI 3019
Query 2953 VTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLV 3012
V T YCR G CE +E GIC + + WVLNN++YR++ G FCG D +L F+ L+
Sbjct 3020 VRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQFFSSLI 3079
Query 3013 QPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLV 3072
+P+ ++AS + G I+AI+V YY +K +R FG+Y VV N +++ ++F +L +
Sbjct 3080 RPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVF 3139
Query 3073 PAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHW 3132
Y VY+ FY Y+T YF +++S + HLQW M+ I+PFW YV + H W
Sbjct 3140 QVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVLW 3199
Query 3133 FFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYK 3192
F+ +++ N STFEE +L TF++ K+ Y +L++ + YNRYL+LYNKY+
Sbjct 3200 LFSYC--RKIGVNVCNDSTFEETSLTTFMITKDSYCRLKNS--VSDVAYNRYLSLYNKYR 3255
Query 3193 YFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSG 3251
Y+SG +DT +YREAAC LAKA+ F+ N+G DVLYQPP S++++ LQSG KM P+
Sbjct 3256 YYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPTS 3315
Query 3252 KVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAG 3311
K+E C+V VT G+ TLNGLWLDD VYCPRHVIC + +M P+Y LL R + F + +G
Sbjct 3316 KIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDFTIMSG 3375
Query 3312 NVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMR 3371
+ L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + MR
Sbjct 3376 RMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAFHVTMR 3435
Query 3372 PNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTA 3431
++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q
Sbjct 3436 SSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYRDAQVV 3495
Query 3432 QAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILG 3491
Q D T+NV+AWLYAA++N WF+ ++ DFN+ AM + + D V L
Sbjct 3496 QLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADLV--LD 3553
Query 3492 PLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKK 3551
L++ TG+++ + AA+K L G GR ILGS EDE P DV +Q +GV Q K K+
Sbjct 3554 ALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTKR 3612
Query 3552 IVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHA 3611
+K T +W+L++ I+ +W++F ++ + + TL ++ + MLLVKHKH
Sbjct 3613 FIKETIYWILISTFLFSCIISAFVKWTIFMYINTH-MIGVTLCVLCFVSFMMLLVKHKHF 3671
Query 3612 FLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLI 3670
+L ++++P L T+ Y N +V + WL +++ + + V I
Sbjct 3672 YLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYEVFYGCILCVFAI 3731
Query 3671 LMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMF 3730
+T ++ D ++ + ++TL+ Y+G+ L++ + ++ + + Y+ +
Sbjct 3732 FITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTWTTILSLA 3789
Query 3731 LARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDY 3790
+A+ IV + F ++ I+L Y F+GY CY+G F LLN FR+ +GVY+Y
Sbjct 3790 IAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMGVYNY 3848
Query 3791 LVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLL 3850
+S QE RYMN+ GL PP++S +A LN+KLLGIGG P I+V+ +QSK++DVKC +VVLL
Sbjct 3849 KISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCANVVLL 3908
Query 3851 SVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------I 3904
+ LQ L V S+S+LW C LHN+IL D + AF+K+ LL VL + AVD I
Sbjct 3909 NCLQHLHVASNSRLWQYCSILHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDTKCLASI 3968
Query 3905 NRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNV 3963
+ + ++ + + LQA+ SEF ++ S+ Y A++ A +G ++ +K+L+K+ N+
Sbjct 3969 DEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNI 4028
Query 3964 AKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALN 4023
AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN
Sbjct 4029 AKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALN 4088
Query 4024 NIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADS 4083
+I++NA GCVPLN IP A L +++PD + D YA ++W IQ V DAD
Sbjct 4089 SILDNAVKGCVPLNAIPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQTVQDADG 4148
Query 4084 KIVQLSEINMDNSPNLAWPLIVTALRANS--AVKLQNNELSPVALRQMSCAAGTTQTACT 4141
QL++I++D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4149 INKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDMNCNI 4204
Query 4142 DDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPK 4201
YYNN GR V A+LSD LK+ + K DG + EL+PPC+F KG K
Sbjct 4205 PTQ--CYYNNGSSGRIVYAVLSDVDGLKYTKIIKDDGNCVV-LELDPPCKFSIQDVKGLK 4261
Query 4202 VKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYL 4261
+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VDP K Y DY+
Sbjct 4262 IKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKTYLDYI 4321
Query 4262 ASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCD 4321
GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+ G C
Sbjct 4322 QQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDVDGLCK 4381
Query 4322 LKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVC 4381
L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D FLNRV
Sbjct 4382 LRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SGVAVQSKD-LNFLNRVR 4438
Query 4382 GVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFV 4440
G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D++GN LD +FV
Sbjct 4439 GTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDGNKLDKFFV 4498
Query 4441 VKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYAL 4500
VKR + Y E+T Y L K C VA HDFF F +DG VPHI R+ L+KYTM DL YAL
Sbjct 4499 VKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRKNLSKYTMLDLCYAL 4558
Query 4501 RHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQ 4560
RHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG ++LL TV
Sbjct 4559 RHFDCNDCSVLCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFNRALLNTVS 4618
Query 4561 FCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRAL 4620
F D + G+VGVLTLDNQDL G WYDFGDF+Q APG GV + DSYYS +MP+LT+ L
Sbjct 4619 FADTLVKVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMPMLTMCHVL 4678
Query 4621 AAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCA 4680
E ++ ++DL++YDFT+ +L LF++YFKYW YHPN ++C +DRCI+HCA
Sbjct 4679 DCELFVNDS----YRQFDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDNDRCIIHCA 4734
Query 4681 NFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKEL 4740
NFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+L
Sbjct 4735 NFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHRYRLSLKDL 4794
Query 4741 LVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKE 4800
L+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F SKG FKE
Sbjct 4795 LLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFVKSKGLFKE 4854
Query 4801 GSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINAN 4860
GS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGGCI A+
Sbjct 4855 GSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGGCIPAS 4914
Query 4861 QVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAK 4920
QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMNLKYAISAK
Sbjct 4915 QVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMNLKYAISAK 4974
Query 4921 NRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
NRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV+
Sbjct 4975 NRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRHLIKDVDN 5034
Query 4981 PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGG 5040
P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ RFYRLANECAQVLSE+VMCGG
Sbjct 5035 PVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVLSEIVMCGG 5094
Query 5041 SLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECL 5100
YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNLQ RLY +
Sbjct 5095 CYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNLQKRLYSNV 5154
Query 5101 YRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNN 5160
YR VD+ FV+E+Y +L KHFSMMILSDD VVCYNS+YA++G +A+I F+ VLYYQNN
Sbjct 5155 YRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYASKGYIANISVFQQVLYYQNN 5214
Query 5161 VFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTD 5220
VFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCFVDD++KTD
Sbjct 5215 VFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCFVDDLLKTD 5274
Query 5221 GTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDN 5280
L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD YSV+L+ +
Sbjct 5275 SVLLIERFVSLAIDAYPLVHHENEEYQKVFRVYLEYIKKLYNDLGNQILDSYSVILSTCD 5334
Query 5281 TSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSH 5340
++ + FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV++T+H
Sbjct 5335 GLKFTDESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHVMATNH 5394
Query 5341 KLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVG 5400
K VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFGLYK +C G
Sbjct 5395 KYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFGLYKQSCTG 5454
Query 5401 SDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLS 5460
S + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY AT++E++S
Sbjct 5455 SPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYASATIQEIVS 5514
Query 5461 DRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKL 5520
DRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V YR TTTYKL
Sbjct 5515 DREIILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYYRATTTYKL 5574
Query 5521 NVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKY 5578
++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y ++ F +NVANYQ +GM++Y
Sbjct 5575 SIGDVFVLTSHSVANLSAPTLVPQENYASIRFSSVY---SVPLLFQTNVANYQHIGMKRY 5631
Query 5579 STLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPAR 5638
T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RIIPA+
Sbjct 5632 CTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNINDCTRIIPAK 5691
Query 5639 ARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYV 5698
RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NAR++AKHYV
Sbjct 5692 VRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINARVKAKHYV 5751
Query 5699 YIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVY 5758
YIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV+TVSALVY
Sbjct 5752 YIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIVETVSALVY 5811
Query 5759 DNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNS 5818
DNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W AVFISPYNS
Sbjct 5812 DNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSAVFISPYNS 5871
Query 5819 QNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMS 5878
QN VA +ILG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK GI C+MS
Sbjct 5872 QNYVAKRILGVQTQTVDSAQGSEYDYVIYSQTAETAHSINVNRFNVAITRAKKGIFCVMS 5931
Query 5879 DRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKT 5937
+ L++ L F +L + + TL + T LFKDCSK G HP AP+ LSVD K+K
Sbjct 5932 NMQLFESLNFITLPLDKIQNQTLSRLHCTTNLFKDCSKNFLGYHPAHAPSFLSVDDKYKV 5991
Query 5938 -EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGC 5996
E L V + +TY RLIS+MGFK++ ++GY FIT++EAI+ VR W+GFDVEG
Sbjct 5992 NEDLAVCLNICEPVLTYSRLISLMGFKLDLTLDGYSKFFITKDEAIKRVRGWVGFDVEGA 6051
Query 5997 HATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMY 6056
HATRD +GTN PLQ+GFSTGV+ V TG + F R AK PPGD FKHLIPLM
Sbjct 6052 HATRDNIGTNFPLQIGFSTGVDFVVEATGLFAERDCYIFKRTVAKAPPGDNFKHLIPLMS 6111
Query 6057 KGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRA 6116
KG W+VVRI+IVQMLSD L LSD VVF+ W+ FELT ++YF K+G E C +C RA
Sbjct 6112 KGQKWDVVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELNCDVCPNRA 6171
Query 6117 TCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDA 6176
TC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD C VH AHVAS DA
Sbjct 6172 TCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKGAHVASSDA 6231
Query 6177 IMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGN 6236
IMTRCLA+++CF K V+W++EYPII +E+ +N++CR +Q +++K+A+L +++ + +DIGN
Sbjct 6232 IMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRYNLCYDIGN 6291
Query 6237 PKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPA 6296
PK I CV + E+KFYDA P +++LFY Y H D F DG+C+FWNCNVD+YP+
Sbjct 6292 PKGIACVK--DYEFKFYDASPV---VKSVKQLFYVYDVHKDNFKDGLCMFWNCNVDKYPS 6346
Query 6297 NAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCES 6356
N+IVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFYYSD+PC
Sbjct 6347 NSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFYYSDTPCVY 6406
Query 6357 HGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQF 6416
+DYVPL+SATCITRCNLGGAVC HA +Y +YL++YN+ +AGF+ W+YK F
Sbjct 6407 VDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEDYCKYLESYNVATTAGFTFWVYKTF 6466
Query 6417 DTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKT 6476
D YNLWNTFT LQSLENV YN+VN GH+DG GE P +I+N+ V K++ +D IF+N T
Sbjct 6467 DFYNLWNTFTMLQSLENVIYNLVNAGHYDGRIGELPCAIMNDKVVVKINNVDTVIFKNNT 6526
Query 6477 TLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDI 6536
+LP N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +++ ST GVC TD+
Sbjct 6527 SLPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVCKYTDL 6586
Query 6537 AKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTL 6596
+ +L VLFDGR G ++ FR ARNGV I+ G + L+ KGP +A +NGV +
Sbjct 6587 ------NFIENLNVLFDGRDNGALEAFRKARNGVFISTGKLSSLSMIKGPQRADLNGVIV 6640
Query 6597 --IGE-SVKTQFNYFKKVDGIIQQLPE-------------------------------TY 6622
+GE +V+ F K D +I + T
Sbjct 6641 DKVGELNVEFWFAMRKDGDDVIFSRADSLSPSHYWSPQGNLGGNCAGNASGNDALARFTI 6700
Query 6623 FTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIG 6682
FTQSR L F+PRS +E DF+++ FI +Y LE YAF+HIVYG F++ +GGLHL+IG
Sbjct 6701 FTQSRVLSTFEPRSDLERDFIDMEDSLFIAKYGLEDYAFDHIVYGSFNYKVIGGLHLLIG 6760
Query 6683 LAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV 6742
L +R + S L +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS +L+
Sbjct 6761 LFRRLKKSNLVIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVVIVKSLNLNC 6820
Query 6743 ISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDL 6802
+SKVV + +D+ + FMLWC D + TFYPK+QA+ W+PG +MP LYK + LE+ L
Sbjct 6821 VSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATSDWKPGYSMPVLYKYLNVPLERVSL 6880
Query 6803 QNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQ 6862
NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+AVLRQ
Sbjct 6881 WNYGKAINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEVAPGSAVLRQ 6940
Query 6863 WLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKE 6922
WLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TK++ N SK+
Sbjct 6941 WLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKNIGDYNVSKD 7000
Query 6923 GFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLI 6982
GFFTY+C I+ KL+LGGS+A+KITE SWNADLYKLM +F++WT F TNVNASSSE FLI
Sbjct 7001 GFFTYICYLIRDKLSLGGSVAIKITEFSWNADLYKLMSYFAFWTVFCTNVNASSSEGFLI 7060
Query 6983 GANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQI 7042
G NYLGK +IDG MHANY+FWRN+ +YSLFDMSKF LKL GTAV++L+ +Q+
Sbjct 7061 GINYLGKSCFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMSKFSLKLAGTAVVNLRPDQL 7120
Query 7043 NDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
ND++YSL+E+G+L++R+ + + D LVN
Sbjct 7121 NDLVYSLIERGKLLVRDTRKEIFVGDSLVNT 7151
Score = 273 bits (699), Expect = 4e-71, Method: Composition-based stats.
Identities = 150/930 (16%), Positives = 296/930 (32%), Gaps = 148/930 (16%)
Query 141 KSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPLDC 200
+D D D + K+ A L R+ G +VD C G DC
Sbjct 185 FKFDDYDFSVEDAYAEVHAEPKGKYSQKAYA-LLRQYRGIKPVLFVDQYGCDYSGKLADC 243
Query 201 IKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKS 259
A S+ + ++ + +AW R + QT I
Sbjct 244 ---LQAYGHYSLQDMRQKQSVWLANCDFDIV------VAWHVVRDSRFVMRLQTIATICG 294
Query 260 AKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNNMHLST 319
K + + V ++ K M V +++
Sbjct 295 IKYVAQPTEDVVDGAVVIREPVHLLSADAIVLKLPSLM----KVMTHMDDFSIKSIYNVD 350
Query 320 LMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYLPTNAVVKMPCPACQDPEIG 379
L C + + C +N G + + + C D
Sbjct 351 LCDCGFVMQYGYV----------DCFNDNCDFYGWVSGNMM--DGFSCPLCCTVYDSSEV 398
Query 380 PEHS---VADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADIGSGHT 436
S + + T +G V G YW PR
Sbjct 399 KAQSSGVIPENPVLFTNSTDTVNPDSFNLYGYSV-TPFGSC---IYWSPRP--------- 445
Query 437 GITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDY 496
G+ +++ + ++ + + S +T
Sbjct 446 GLWIPIIKSSVKSYDDL----------------------VYSGVVGCKSIVKETALITHA 483
Query 497 KSFKTIVESCGNYKVTKGKPVKGAW------NIGQQRSVLTPLCGFPSQAAGVIR--SIF 548
+ CGN + V +W N G +L + F + A ++
Sbjct 484 LYLDYVQCKCGNLEQNHILGVNNSWCRQLLLNRGDYNMLLKNIDLFVKRRADFACKFAVC 543
Query 549 ARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYT-------SDLLTNSVIIMAYV 601
+LDG+ +S L+ + ++ S +++ + M +
Sbjct 544 GDGF-------------VPFLLDGLIPRSYYLIQSGIFFTSLMSQFSQEVSDMCLKMCIL 590
Query 602 TGGLVQQTSQWLSNLLGTTVEK--------LRPIFEWIEAKLSAGVEFLKDAWEILKFLI 653
V + ++ + + V + + + W L A W + + L+
Sbjct 591 FMDRVSVATFYIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDASAP--ATGWLLYQ-LL 647
Query 654 TGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAK----LRSLNL---- 705
G+F + + + I D K ++ ++ ++ VT+ K L+++N
Sbjct 648 NGLFVVSQANFNFVA-LIPDYAKILVNKFYTFFKLLLECVTVDVLKDMPVLKTINGLVCI 706
Query 706 -GEVFIAQSKGLYRQCIRGKEQLQLLMPLKA-PKEVTFLEGDSHDTVLTSEEVVLKNGEL 763
G F S GL ++P A +++ F EG +E V++++ +
Sbjct 707 VGNKFYNVSTGLI---------PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVI 750
Query 764 EALETPVDSFT---NGAIVGTPVCVNGLMLLEIKDKEQYCALSP-GLLATNNVFRLKGGA 819
E +++ + S+ V ++ + + + DK ++ + + +R
Sbjct 751 ENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGDKFFPIVMNDKNICLLDQAWRFPCAG 810
Query 820 PIKGVTFGED-TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAE 878
+ V F E V E+ V++ F+LD D +L + CS + VE G V +F VV +
Sbjct 811 --RKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCD 868
Query 879 AVVKTLQPVSD---LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDD 935
A+ L D + + L++ + YLFD+AG+E +SRMYC+F D E+
Sbjct 869 AIENALNSCKDHPVVGYQVRAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVIS 928
Query 936 AECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEP-- 993
+E E+ ID E ++D + E V + ++ED + + ++
Sbjct 929 SEAVEDTIDGVVEDTINDDEDVVTGDND----DEDVVTGDNDDEDVVTGDNDDEDVVTGD 984
Query 994 -EPEPTPEEPVNQFTGYLKLTDNVAIKCVD 1022
+ E + D+ + D
Sbjct 985 NDDEDVVTGDNDDEDVVTGDNDDEDVVTGD 1014
Score = 172 bits (436), Expect = 1e-40, Method: Composition-based stats.
Identities = 55/157 (35%), Positives = 79/157 (50%), Gaps = 2/157 (1%)
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
L +T NV DI+ A+ VIVN AN H+ HGGGVA A+ A KE+ +
Sbjct 1328 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1387
Query 1070 KLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDILLAPLL 1127
K G VG + +G L K L++VGP+ + LL AY++ N+ D L+ L+
Sbjct 1388 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1447
Query 1128 SAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
SAGIF SL + V QV + N+K ++ +
Sbjct 1448 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDII 1484
Score = 52.4 bits (124), Expect = 2e-04, Method: Composition-based stats.
Identities = 48/205 (23%), Positives = 76/205 (37%), Gaps = 18/205 (9%)
Query 1573 PTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTL----DESFLGRYMSALN 1628
D +I N + DD F+ Y L D ++S +
Sbjct 1049 DVVTGDNDDEEIVTGDNDDQIVVTGDDVDDIESVYDFDTYKALLVFNDVYNDALFVSYGS 1108
Query 1629 HTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFC 1688
+ + +V GL S NC+L SVLL +Q+L KF A++ + + G +F
Sbjct 1109 SVETETYFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFV 1168
Query 1689 ALILAYSNKTVGEL--GDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVM 1746
+L K + G V + L ++ N C CG + L G++AV
Sbjct 1169 DYLLTTIPKAIVLPQGGYVADFAYWFLNQFDI---NAYANWCCLKCGF-SFDLNGLDAVF 1224
Query 1747 YMGTLSYDNLKTGVSIPCVCGRDAT 1771
+ G + VS C CG + T
Sbjct 1225 FYGDI--------VSHVCKCGHNMT 1241
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 25/157 (16%), Positives = 44/157 (28%), Gaps = 15/157 (10%)
Query 1194 EKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMS 1253
+V D+ + +V +L + + + E +
Sbjct 1331 TPNVCFVKGDIINVARLVKADVIVNPANGH-----MLHGGGVAKAIAVAAGKKFSKETAA 1385
Query 1254 FLEKDAPYMVGDVITSGD------ITCVVIPSKKAGGTTE--MLSRALKKVPVDEYITTY 1305
++ VGD S I +V P + G +L+RA K ++ Y
Sbjct 1386 MVKSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKH--LNNYDCCL 1443
Query 1306 PGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEE 1342
AG A +L N KE+
Sbjct 1444 STLISAGIFSVPADVSLTYLLGVVDKQVILVSNNKED 1480
>sp|P0C6X4|R1AB_CVHN5 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=rep PE=3 SV=1
Length=7132
Score = 7647 bits (19842), Expect = 0.0, Method: Composition-based stats.
Identities = 2707/5671 (48%), Positives = 3650/5671 (64%), Gaps = 167/5671 (3%)
Query 1488 RDWSYSGQ----RTELGVEFLKRGDKIVYHTLESPVEFHLDGEV--LSLDKLKSLLSLRE 1541
+DW + V++ + + I + + DG +++++ LL
Sbjct 1543 KDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLL---- 1598
Query 1542 VKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSD 1601
K I V TVD N + + + +G+ G + DG DVTK+K + K + +
Sbjct 1599 AKKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENL 1658
Query 1602 DTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
A + D+ L Y + L KW G S + + NNCY++ L LQ
Sbjct 1659 SLADISAVQSSFGFDQQQLLAYYNFL-TVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQ 1717
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
+ +KFN QEA+Y RAG AL+LA + E D + + +L+ A+L A
Sbjct 1718 HINLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGA 1777
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
L ++C CG K + GV+AVM+ GTL+ +L G I C C + + F
Sbjct 1778 ICELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAG-RIVHCTKLNVPF 1835
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S P L + AN + G GHYTH+ D + K + G +T
Sbjct 1836 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1893
Query 1842 DVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLPN 1899
D Y K + T T +Y LD V P L YY + YYT+ I +
Sbjct 1894 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYTKPIIKAQFKPFAKVD 1953
Query 1900 ASFDNFKLTCSNTKFADDLNQMTGFTKP-ASRELSVTFFPDLNGDVVAIDYRHYSASFKK 1958
+ NFKL + LN GF E VT +P GDVV Y + K
Sbjct 1954 GVYTNFKLVGHD--ICAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2011
Query 1959 GAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKP-VDTSNSFEVLAVEDTQGMDNLA 2017
G + KP++W + + + + KP + N + VL+V+ +
Sbjct 2012 GCETFGKPVIWFCHDEASLNSLT---------YFNKPSFKSENRYSVLSVDSV------S 2056
Query 2018 CESQQPTSEEVVENPTIQKEV-IECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAY 2076
ESQ V+E+ KEV ++ KT ++ +I+ + +KV + L D+ Y
Sbjct 2057 EESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDMY 2116
Query 2077 VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKR 2136
+ + NELS + T+ + I + L ++ Q + R
Sbjct 2117 LTGCDYVVWVANELSRLVKSPTVREYIRYGIKPITIPIDLLCLRD-DNQTLLVPKIFKAR 2175
Query 2137 LAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVK 2196
+ F ++ ++F +F L FT T IA ++ L L +
Sbjct 2176 AIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAFQTFR 2229
Query 2197 SPKFSKLFTIAMWLLLLSICLGSLICVTAAFG----------------VLLSNFGAPSYC 2240
F K F + + L + + + F + + FG + C
Sbjct 2230 WSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTIC 2289
Query 2241 NGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL--DLTIL 2298
+ +L + T FC GSF C +C SG D LD+Y A++ +Q + L ++++
Sbjct 2290 DFYSKLGVG----FTSHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDYVSLV 2345
Query 2299 GLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSA 2356
L E V+ Y L+T +FY L +Q+F + F+ + WL+ FI+ + M P
Sbjct 2346 KLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAFV 2405
Query 2357 MVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYAN 2416
++R YI + Y + HI+ GC + C+ CYKRN + RV+C+TIV G+ R + + AN
Sbjct 2406 LLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITAN 2465
Query 2417 GGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNG 2476
GG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2466 GGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVGC 2525
Query 2477 ALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASV 2536
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + + D + +A V
Sbjct 2526 MMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDA--DRANFLNAVV 2583
Query 2537 YYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSE 2596
+Y+Q + +PILL+D+ L++ + V+ MFD YVDTF + F V + V AH+
Sbjct 2584 FYAQSLYRPILLVDKKLITTACNGISVTQIMFDVYVDTFMSHFDVDRKSFNNFVNIAHAS 2643
Query 2597 LAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYN 2655
L +GV L+ VL TFV R+ +D+DV+T+ + + + + + LE T ++ NN + TY
Sbjct 2644 LREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVPTYL 2703
Query 2656 KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNI 2715
K +N+ DLG I A+H+ VAK N+S IW + + L+ L+ +++ A K +
Sbjct 2704 KSDNIVAADLGVLIQNGAKHVQGNVAKVANISCIWFIDAFNQLTADLQHKLKKACVKTGL 2763
Query 2716 PFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSI 2775
+LT V ++TT SLKGG ++S ++ +L+C + + + ++P +++
Sbjct 2764 KLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPTYSVYK 2820
Query 2776 HDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAA 2833
D + +K I +GV RDI D CFANK FD W+ G Y N CP+V A
Sbjct 2821 SDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDCPIVVA 2880
Query 2834 IITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLA 2893
++ +IG + +P VLR LHFL F++ CYTP I Y+DF S CVL+
Sbjct 2881 VMDEDIGSTMFNVPTKVLR-YGFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVLS 2939
Query 2894 AECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRV 2952
+ CT+FK G P PYCY +++ + Y+ L P TRY L + + I+FP+ EG VR+
Sbjct 2940 SLCTMFKRGDGTPHPYCYTDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVRI 2999
Query 2953 VTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLV 3012
V T YCR G CE +E GIC + + WVLNN++YR++ G FCG D +L F+ L+
Sbjct 3000 VRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDFFDLFYQFFSSLI 3059
Query 3013 QPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLV 3072
+P+ ++AS + G I+AI+V YY +K +R FG+Y VV N +++ ++F +L +
Sbjct 3060 RPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVF 3119
Query 3073 PAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHW 3132
Y VY+ FY Y+T YF +++S + HLQW M+ I+PFW YV + H W
Sbjct 3120 QVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVLW 3179
Query 3133 FFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYK 3192
F+ +++ N + STFEE +L TF++ K+ Y +L++ + YNRYL+LYNKY+
Sbjct 3180 LFSYC--RKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNS--VSDVAYNRYLSLYNKYR 3235
Query 3193 YFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSG 3251
Y+SG +DT +YREAAC LAKA+ F+ N+G DVLYQPP S++++ LQSG KM P+
Sbjct 3236 YYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPTS 3295
Query 3252 KVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAG 3311
K+E C+V VT G+ TLNGLWLDD VYCPRHVIC + +M P+Y LL R + F + +G
Sbjct 3296 KIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDFTIMSG 3355
Query 3312 NVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMR 3371
+ L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + MR
Sbjct 3356 RMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAFHVTMR 3415
Query 3372 PNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTA 3431
++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q
Sbjct 3416 SSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGNFYGPYRDAQVV 3475
Query 3432 QAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILG 3491
Q D T+NV+AWLYAA++N WF+ ++ DFN+ AM + + D V L
Sbjct 3476 QLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADLV--LD 3533
Query 3492 PLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKK 3551
L++ TG+++ + AA+K L G GR ILGS EDE P DV +Q +GV Q K K+
Sbjct 3534 ALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTKR 3592
Query 3552 IVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHA 3611
+K T +W+L++ I+ +W++F ++ + + TL ++ + MLLVKHKH
Sbjct 3593 FIKETIYWILISTFLFSCIISAFVKWTIFMYINTH-MIGVTLCVLCFVSFMMLLVKHKHF 3651
Query 3612 FLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLI 3670
+L ++++P L T+ Y N +V + WL +++ + + V I
Sbjct 3652 YLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYEVFYGCILCVFAI 3711
Query 3671 LMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMF 3730
+T ++ D ++ + ++TL+ Y+G+ L++ + ++ + + Y+ +
Sbjct 3712 FITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTWTTILSLA 3769
Query 3731 LARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDY 3790
+A+ IV + F ++ I+L Y F+GY CY+G F LLN FR+ +GVY+Y
Sbjct 3770 IAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMGVYNY 3828
Query 3791 LVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLL 3850
+S QE RYMN+ GL PP++S +A LN+KLLGIGG P I+V+ +QSK++DVKC +VVLL
Sbjct 3829 KISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCANVVLL 3888
Query 3851 SVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------I 3904
+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL S AVD I
Sbjct 3889 NCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFSNPAAVDTKCLASI 3948
Query 3905 NRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNV 3963
+ + ++ + + LQA+ SEF ++ S+ Y A++ A +G ++ +K+L+K+ N+
Sbjct 3949 DEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNI 4008
Query 3964 AKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALN 4023
AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN
Sbjct 4009 AKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALN 4068
Query 4024 NIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADS 4083
+I++NA GCVPL+ IP A L +++PD + D TYA ++W IQ V DAD
Sbjct 4069 SILDNAVKGCVPLSAIPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQTVQDADG 4128
Query 4084 KIVQLSEINMDNSPNLAWPLIVTALRANS--AVKLQNNELSPVALRQMSCAAGTTQTACT 4141
QL++I++D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4129 INKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDINCNI 4184
Query 4142 DDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPK 4201
YYNN GR V A+LSD LK+ + K DG + EL+PPC+F KG K
Sbjct 4185 PTQ--CYYNNVSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFSIQDVKGLK 4241
Query 4202 VKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYL 4261
+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VDP K Y DY+
Sbjct 4242 IKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKTYLDYI 4301
Query 4262 ASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCD 4321
GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+ G C
Sbjct 4302 QQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDVDGICK 4361
Query 4322 LKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVC 4381
L+GK+VQ+P DP+ + L + VC VCG W+ CSC + + FLNRV
Sbjct 4362 LRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG--SSVAVQSKDLNFLNRVR 4418
Query 4382 GVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFV 4440
G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D++GN LD +FV
Sbjct 4419 GTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDGNKLDKFFV 4478
Query 4441 VKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYAL 4500
VKR + Y E+T Y L K C VA HDFF F +DG VPHI R+ L+KYTM DL YAL
Sbjct 4479 VKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRRNLSKYTMLDLCYAL 4538
Query 4501 RHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQ 4560
RHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG ++LL TV
Sbjct 4539 RHFDRNDCSILCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFNRALLNTVI 4598
Query 4561 FCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRAL 4620
F D + + G+VGVLTLDNQDL G WYDFGDF+Q APG GV + DSYYS +MP+LT+ L
Sbjct 4599 FADTLVEVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMPMLTMCHVL 4658
Query 4621 AAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCA 4680
E ++ ++DL++YDFT+ +L LF++YFKYW YHPN ++C +DRCI+HCA
Sbjct 4659 DCELFVNDS----YRQFDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDNDRCIIHCA 4714
Query 4681 NFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKEL 4740
NFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+L
Sbjct 4715 NFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHRYRLSLKDL 4774
Query 4741 LVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKE 4800
L+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F SKG FKE
Sbjct 4775 LLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFVKSKGLFKE 4834
Query 4801 GSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINAN 4860
GS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGGCI A+
Sbjct 4835 GSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGGCIPAS 4894
Query 4861 QVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAK 4920
QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMNLKYAISAK
Sbjct 4895 QVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMNLKYAISAK 4954
Query 4921 NRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
NRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV+
Sbjct 4955 NRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRHLIKDVDN 5014
Query 4981 PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGG 5040
P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ RFYRLANECAQVLSE+VMCGG
Sbjct 5015 PVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVLSEIVMCGG 5074
Query 5041 SLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECL 5100
YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNLQ RLY +
Sbjct 5075 CYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNLQKRLYSNV 5134
Query 5101 YRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNN 5160
YR VD+ FV+E+Y +L KHFSMMILSDD VVCYNS+YA +G +A+I F+ VLYYQNN
Sbjct 5135 YRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYANKGYIANISAFQQVLYYQNN 5194
Query 5161 VFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTD 5220
VFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCFVDD++KTD
Sbjct 5195 VFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCFVDDLLKTD 5254
Query 5221 GTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDN 5280
L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD YSV+L+ +
Sbjct 5255 SVLLIERFVSLAIDAYPLVYHENEEYQKVFRVYLEYIKKLYNDLGTQILDSYSVILSTCD 5314
Query 5281 TSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSH 5340
++ E FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV++T+H
Sbjct 5315 GLKFTEESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHVMATNH 5374
Query 5341 KLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVG 5400
K VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFGLYK +C G
Sbjct 5375 KYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFGLYKQSCTG 5434
Query 5401 SDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLS 5460
S + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY AT++E++S
Sbjct 5435 SPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYASATIQEIVS 5494
Query 5461 DRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKL 5520
DRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V YR TTTYKL
Sbjct 5495 DREVILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYYRATTTYKL 5554
Query 5521 NVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKY 5578
++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y ++ F +NVANYQ +GM++Y
Sbjct 5555 SIGDVFVLTSHSVASLSAPTLVPQENYASIRFSSVY---SVPLVFQNNVANYQHIGMKRY 5611
Query 5579 STLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPAR 5638
T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RIIPA+
Sbjct 5612 CTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNINDCTRIIPAK 5671
Query 5639 ARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYV 5698
RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NAR++AKHYV
Sbjct 5672 VRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINARIKAKHYV 5731
Query 5699 YIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVY 5758
YIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV+TVSALVY
Sbjct 5732 YIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIVETVSALVY 5791
Query 5759 DNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNS 5818
DNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W AVFISPYNS
Sbjct 5792 DNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSAVFISPYNS 5851
Query 5819 QNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMS 5878
QN VA ++LG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK GI C+MS
Sbjct 5852 QNYVAKRVLGVQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKGIFCVMS 5911
Query 5879 DRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKT 5937
+ L++ L F +L + + TL + T LFKDCSK G HP AP+ L+VD K+K
Sbjct 5912 NMQLFESLNFITLPLDKIQNQTLPRLHCTTNLFKDCSKSCLGYHPAHAPSFLAVDDKYKV 5971
Query 5938 EG-LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGC 5996
L V++ +TY RLIS+MGFK++ ++GY +FIT++EAI+ VR W+GFDVEG
Sbjct 5972 NENLAVNLNICEPVLTYSRLISLMGFKLDLTLDGYSKLFITKDEAIKRVRGWVGFDVEGA 6031
Query 5997 HATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMY 6056
HATR+ +GTN PLQ+GFSTGV+ V TG + F + AK PPG++FKHLIPLM
Sbjct 6032 HATRENIGTNFPLQIGFSTGVDFVVEATGLFAERDCYTFKKTVAKAPPGEKFKHLIPLMS 6091
Query 6057 KGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRA 6116
KG W++VRI+IVQMLSD L LSD VVF+ W+ FELT ++YF K+G E C +C RA
Sbjct 6092 KGQKWDIVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELNCNVCSNRA 6151
Query 6117 TCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDA 6176
TC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD C VH AHVAS DA
Sbjct 6152 TCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKGAHVASADA 6211
Query 6177 IMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGN 6236
IMTRCLA+++CF K V+W++EYPII +E+ +N++CR +Q +++K+A+L +++ + +DIGN
Sbjct 6212 IMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRYNLCYDIGN 6271
Query 6237 PKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPA 6296
PK + CV + E+KFYDA P A +++LFY Y H D F DG+C+FWNCNVD+YP+
Sbjct 6272 PKGLACVK--DYEFKFYDAFPV---AKSVKQLFYVYDVHKDNFKDGLCMFWNCNVDKYPS 6326
Query 6297 NAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCES 6356
N+IVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFYYSD+PC
Sbjct 6327 NSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFYYSDTPCVY 6386
Query 6357 HGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQF 6416
+DYVPL+SATCITRCNLGGAVC HA EY YL++YN++ +AGF+ W+YK F
Sbjct 6387 VDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEEYCNYLESYNIVTTAGFTFWVYKTF 6446
Query 6417 DTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKT 6476
D YNLWNTFT LQSLENV YN+VN GH+DG GE P +I+N+ V K++ +D IF+N T
Sbjct 6447 DFYNLWNTFTTLQSLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKINNVDTVIFKNNT 6506
Query 6477 TLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDI 6536
+ P N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +++ ST GVC TD+
Sbjct 6507 SFPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVCKYTDL 6566
Query 6537 AKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTL 6596
+L +LFDGR G ++ FR ARNGV I+ + L+ KGP +A +NGV +
Sbjct 6567 ------KFIENLNILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKGPQRADLNGVIV 6620
Query 6597 --IGE-SVKTQFNYFKKVDGIIQQLPE-------------------------------TY 6622
+GE V+ F K D +I + T
Sbjct 6621 DKVGELKVEFWFAMRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGNVIGNDALTRFTI 6680
Query 6623 FTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIG 6682
FTQSR L F+PRS +E DF+++ + FI +Y LE YAF+HIVYG F+H +GGLHL+IG
Sbjct 6681 FTQSRVLSSFEPRSDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFNHKVIGGLHLLIG 6740
Query 6683 LAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV 6742
L +R + S L +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS +LS
Sbjct 6741 LFRRLKKSNLLIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVSIVKSLNLSC 6800
Query 6743 ISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDL 6802
+SKVV + +D+ + FMLWC D + TFYPK+QA+ W+PG +MP LYK + LE+ L
Sbjct 6801 VSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATNDWKPGYSMPVLYKYLNVPLERVSL 6860
Query 6803 QNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQ 6862
NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+AVLRQ
Sbjct 6861 WNYGKPINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEVAPGSAVLRQ 6920
Query 6863 WLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKE 6922
WLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TK++ N SK+
Sbjct 6921 WLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKNIGDYNVSKD 6980
Query 6923 GFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLI 6982
GFFTY+C I+ KL+LGGS+A+KITE SWNADLYKLM F++WT F TNVNASSSE FLI
Sbjct 6981 GFFTYICHLIRDKLSLGGSVAIKITEFSWNADLYKLMSCFAFWTVFCTNVNASSSEGFLI 7040
Query 6983 GANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQI 7042
G NYLGK +IDG MHANY+FWRN+ +YSLFDM+KF LKL GTAV++L+ +Q+
Sbjct 7041 GINYLGKSSFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMTKFSLKLAGTAVVNLRPDQL 7100
Query 7043 NDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
ND++YSL+E+G+L++R+ + + D LVN
Sbjct 7101 NDLVYSLIERGKLLVRDTRKEIFVGDSLVNT 7131
Score = 265 bits (678), Expect = 9e-69, Method: Composition-based stats.
Identities = 148/930 (16%), Positives = 296/930 (32%), Gaps = 148/930 (16%)
Query 141 KSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPLDC 200
+D D + K+ A L R+ G +VD C G DC
Sbjct 185 FKFDDYDFSVEAAYAEVHAEPKGKYSQKAYA-LLRQYRGIKPVLFVDQYGCDYSGKLADC 243
Query 201 IKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKS 259
A S+ + ++ + +AW R + QT I
Sbjct 244 ---LQAYGHYSLQDMRQKQSVWLANCDFDIV------VAWHVVRDSRFVMRLQTIATICG 294
Query 260 AKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNNMHLST 319
K + + V ++ K M V +++
Sbjct 295 IKYVAQPTEDVVDGDVVIREPVHLLSADAIVLKLPSLM----KVMTHMDDFSIKSIYNVD 350
Query 320 LMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYLPTNAVVKMPCPACQDPEIG 379
L C + + C +N G + + + C D
Sbjct 351 LCDCGFVMQYGYV----------DCFNDNCDFYGWVSGNMM--DGFSCPLCCTVYDSSEV 398
Query 380 PEHS---VADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADIGSGHT 436
S + + T +G V G YW PR
Sbjct 399 KAQSSGVIPENPVLFTNSTDTVNPDSFNLYGYSV-TPFGSC---IYWSPRP--------- 445
Query 437 GITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDY 496
G+ +++ + ++ + + S +T
Sbjct 446 GLWIPIIKSSVKSYDDL----------------------VYSGVVGCKSIVKETALITHA 483
Query 497 KSFKTIVESCGNYKVTKGKPVKGAW------NIGQQRSVLTPLCGFPSQAAGVIR--SIF 548
+ CGN + V +W N G +L + F + A ++
Sbjct 484 LYLDYVQCKCGNLEQNHILGVNNSWCRQLLLNRGDYNMLLKNIDLFVKRRADFACKFAVC 543
Query 549 ARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYT-------SDLLTNSVIIMAYV 601
+LDG+ +S L+ + ++ S +++ + M +
Sbjct 544 GDGF-------------VPFLLDGLIPRSYYLIQSGIFFTSLMSQFSQEVSDMCLKMCIL 590
Query 602 TGGLVQQTSQWLSNLLGTTVEK--------LRPIFEWIEAKLSAGVEFLKDAWEILKFLI 653
V + ++ + + V + + + W L A W + + L+
Sbjct 591 FMDRVSVATFYIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDASAP--ATGWLLYQ-LL 647
Query 654 TGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAK----LRSLNL---- 705
G F + + + + I D K ++ ++ ++ VT+ K L+++N
Sbjct 648 NGFFVVSQANLNFVA-LIPDYAKILVNKFYTFFKLLLECVTVDVLKDMPVLKTINGLVCI 706
Query 706 -GEVFIAQSKGLYRQCIRGKEQLQLLMPLKA-PKEVTFLEGDSHDTVLTSEEVVLKNGEL 763
G F S GL ++P A +++ F EG +E V++++ +
Sbjct 707 VGNKFYNVSTGLI---------PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVI 750
Query 764 EALETPVDSFT---NGAIVGTPVCVNGLMLLEIKDKEQYCALSP-GLLATNNVFRLKGGA 819
E +++ + S+ V ++ + + + DK ++ + ++ +R
Sbjct 751 ENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGDKFFPIVMNDKNICLLDHAWRFPCAG 810
Query 820 PIKGVTFGED-TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAE 878
+ V F E V E+ V++ F+LD D +L + CS + VE G V +F VV +
Sbjct 811 --RKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCD 868
Query 879 AVVKTLQPVSD---LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDD 935
A+ L + + + L++ + YLFD+AG+E +SRMYC+F D E+
Sbjct 869 AIENALNSCKEHPVVGYQVRAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVIS 928
Query 936 AECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEP-- 993
+E E+ ID E ++D + E V + ++ED + + ++
Sbjct 929 SEAVEDTIDGVVEDTINDDEDVVTGDND----DEDVVTGDNDDEDVVTGDNDDEDVVTGD 984
Query 994 -EPEPTPEEPVNQFTGYLKLTDNVAIKCVD 1022
+ E + D+ + D
Sbjct 985 NDDEDVVTGDNDDEDVVTGDNDDEDVVTGD 1014
Score = 172 bits (436), Expect = 1e-40, Method: Composition-based stats.
Identities = 55/157 (35%), Positives = 79/157 (50%), Gaps = 2/157 (1%)
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
L +T NV DI+ A+ VIVN AN H+ HGGGVA A+ A KE+ +
Sbjct 1308 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1367
Query 1070 KLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDILLAPLL 1127
K G VG + +G L K L++VGP+ + LL AY++ N+ D L+ L+
Sbjct 1368 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1427
Query 1128 SAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
SAGIF SL + V QV + N+K ++ +
Sbjct 1428 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDII 1464
Score = 51.2 bits (121), Expect = 6e-04, Method: Composition-based stats.
Identities = 45/177 (25%), Positives = 71/177 (40%), Gaps = 18/177 (10%)
Query 1601 DDTLRSEAFEYYHTL----DESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSV 1656
DD F+ Y L D ++S + + + +V GL S NC+L SV
Sbjct 1057 DDIESIYDFDTYKALLVFNDVYNDALFVSYGSSVETETYFKVNGLWSPTITHTNCWLRSV 1116
Query 1657 LLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGEL--GDVRETMTHLLQ 1714
LL +Q+L KF A++ + + G +F +L K + G V + L
Sbjct 1117 LLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTTIPKAIVLPQGGYVADFAYWFLN 1176
Query 1715 HANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDAT 1771
++ N C CG + L G++AV + G + VS C CG + T
Sbjct 1177 QFDI---NAYANWCCLKCGF-SFDLNGLDAVFFYGDI--------VSHVCKCGHNMT 1221
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 25/157 (16%), Positives = 44/157 (28%), Gaps = 15/157 (10%)
Query 1194 EKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMS 1253
+V D+ + +V +L + + + E +
Sbjct 1311 TPNVCFVKGDIINVARLVKADVIVNPANGH-----MLHGGGVAKAIAVAAGKKFSKETAA 1365
Query 1254 FLEKDAPYMVGDVITSGD------ITCVVIPSKKAGGTTE--MLSRALKKVPVDEYITTY 1305
++ VGD S I +V P + G +L+RA K ++ Y
Sbjct 1366 MVKSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKH--LNNYDCCL 1423
Query 1306 PGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEE 1342
AG A +L N KE+
Sbjct 1424 STLISAGIFSVPADVSLTYLLGVVDKQVILVSNNKED 1460
>sp|P0C6X2|R1AB_CVHN1 Replicase polyprotein 1ab OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=rep PE=3 SV=1
Length=7182
Score = 7641 bits (19827), Expect = 0.0, Method: Composition-based stats.
Identities = 2707/5671 (48%), Positives = 3652/5671 (64%), Gaps = 167/5671 (3%)
Query 1488 RDWSYSGQ----RTELGVEFLKRGDKIVYHTLESPVEFHLDGEV--LSLDKLKSLLSLRE 1541
+DW + V++ + + I + + DG +++++ LL
Sbjct 1593 KDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLL---- 1648
Query 1542 VKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSD 1601
K I V TVD N + + + +G+ G + DG DVTK+K + K + +
Sbjct 1649 AKKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENL 1708
Query 1602 DTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
A + D+ L Y + L KW G S + + NNCY++ L LQ
Sbjct 1709 SLADISAVQSSFGFDQQQLLAYYNFL-TVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQ 1767
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
+ +KFN QEA+Y RAG AL+LA + E D + + +L+ A+L A
Sbjct 1768 HINLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGA 1827
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
L ++C CG K + GV+AVM+ GTL+ +L G I C C + + F
Sbjct 1828 ICELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAG-RIVHCTKLNVPF 1885
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S P L + AN + G GHYTH+ D + K + G +T
Sbjct 1886 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1943
Query 1842 DVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLPN 1899
D Y K + T T +Y LD V P L YY + YYT+ I +
Sbjct 1944 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYTKPIIKAQFKPFAKVD 2003
Query 1900 ASFDNFKLTCSNTKFADDLNQMTGFTKP-ASRELSVTFFPDLNGDVVAIDYRHYSASFKK 1958
+ NFKL + LN GF E VT +P GDVV Y + K
Sbjct 2004 GVYTNFKLVGHD--ICAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2061
Query 1959 GAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKP-VDTSNSFEVLAVEDTQGMDNLA 2017
G + KP++W + + + + KP + N + VL+V+ +
Sbjct 2062 GCETFGKPVIWFCHDEASLNSLT---------YFNKPSFKSENRYSVLSVDSV------S 2106
Query 2018 CESQQPTSEEVVENPTIQKEV-IECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAY 2076
ESQ V+E+ KEV ++ KT ++ +I+ + +KV + L D+ Y
Sbjct 2107 EESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDMY 2166
Query 2077 VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKR 2136
+ + NELS + T+ + I + L ++ Q + R
Sbjct 2167 LTGCDYVVWVANELSRLVKSPTVREYIRYGIKPITIPIDLLCLRD-DNQTLLVPKIFKAR 2225
Query 2137 LAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVK 2196
+ F ++ ++F +F L FT T IA ++ L L +
Sbjct 2226 AIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAFQTFR 2279
Query 2197 SPKFSKLFTIAMWLLLLSICLGSLICVTAAFG----------------VLLSNFGAPSYC 2240
F K F + + L + + + F + + FG + C
Sbjct 2280 WSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTIC 2339
Query 2241 NGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL--DLTIL 2298
+ +L + T FC GSF C +C SG D LD+Y A++ +Q + L ++++
Sbjct 2340 DFYSKLGVG----FTSHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDYVSLV 2395
Query 2299 GLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSA 2356
L E V+ Y L+T +FY L +Q+F + F+ + WL+ FI+ + M P
Sbjct 2396 KLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAFV 2455
Query 2357 MVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYAN 2416
++R YI + Y + HI+ GC + C+ CYKRN + RV+C+TIV G+ R + + AN
Sbjct 2456 LLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITAN 2515
Query 2417 GGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNG 2476
GG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2516 GGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVGC 2575
Query 2477 ALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASV 2536
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + + D + +A V
Sbjct 2576 MMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDA--DRANFLNAVV 2633
Query 2537 YYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSE 2596
+Y+Q + +PILL+D+ L++ + V+ MFD YVDTF + F V + V AH+
Sbjct 2634 FYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVNIAHAS 2693
Query 2597 LAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYN 2655
L +GV L+ VL TFV R+ +D+DV+T+ + + + + + LE T ++ NN + TY
Sbjct 2694 LREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVPTYL 2753
Query 2656 KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNI 2715
K +N+ DLG I A+H+ VAK+ N+S IW + + L+ L+ +++ A K +
Sbjct 2754 KSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDAFNQLTADLQHKLKKACVKTGL 2813
Query 2716 PFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSI 2775
+LT V ++TT SLKGG ++S ++ +L+C + + + ++P +++
Sbjct 2814 KLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFVSLICFI---LLWALLPTYSVYK 2870
Query 2776 HDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAA 2833
D + +K I +GV RDI D CFANK FD W+ G Y N CP+V A
Sbjct 2871 SDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDCPIVVA 2930
Query 2834 IITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLA 2893
++ +IG + +P VLR LHFL F++ CYTP I Y+DF S CVL+
Sbjct 2931 VMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVLS 2989
Query 2894 AECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRV 2952
+ CT+FK G P PYCY +++ + Y+ L P TRY L + + I+FP+ EG VR+
Sbjct 2990 SLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVRI 3049
Query 2953 VTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLV 3012
V T YCR G CE +E GIC + + WVLNN++YR++ G FCG D +L F+ L+
Sbjct 3050 VRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQFFSSLI 3109
Query 3013 QPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLV 3072
+P+ ++AS + G I+AI+V YY +K +R FG+Y VV N +++ ++F +L +
Sbjct 3110 RPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVVVWCINFLMLFVF 3169
Query 3073 PAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHW 3132
Y VY+ FY Y+T YF +++S + HLQW M+ I+PFW YV + H W
Sbjct 3170 QVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVLW 3229
Query 3133 FFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYK 3192
F+ +++ N + STFEE +L TF++ K+ Y +L++ + YNRYL+LYNKY+
Sbjct 3230 LFSYC--RKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNS--VSDVAYNRYLSLYNKYR 3285
Query 3193 YFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSG 3251
Y+SG +DT +YREAAC LAKA+ F+ N+G DVLYQPP S++++ LQSG KM P+
Sbjct 3286 YYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPTS 3345
Query 3252 KVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAG 3311
K+E C+V VT G+ TLNGLWLDD VYCPRHVIC++ +M P+Y LL R + F + +G
Sbjct 3346 KIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCRVTLGDFTIMSG 3405
Query 3312 NVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMR 3371
+ L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + MR
Sbjct 3406 RMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNGRPQGAFHVTMR 3465
Query 3372 PNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTA 3431
++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q
Sbjct 3466 SSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYRDAQVV 3525
Query 3432 QAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILG 3491
Q D T+NV+AWLYAA++N WF+ + DFN+ AM + + D V L
Sbjct 3526 QLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFSQVKADLV--LD 3583
Query 3492 PLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKK 3551
L++ TG+++ + AA+K L G GR ILGS EDE P DV +Q +GV Q K K+
Sbjct 3584 ALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTKR 3642
Query 3552 IVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHA 3611
+K T +W+L++ I+ +W++F ++ + + TL ++ + MLLVKHKH
Sbjct 3643 FIKETIYWILISTFLFSCIISAFVKWTIFMYINTH-MIGVTLCVLCFVSFMMLLVKHKHF 3701
Query 3612 FLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLI 3670
+L ++++P L T+ Y N +V + WL +++ + + V I
Sbjct 3702 YLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYEVFYGCILCVFAI 3761
Query 3671 LMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMF 3730
+T ++ D ++ + ++TL+ Y+G+ L++ + ++ + + Y+ +
Sbjct 3762 FITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTWTTILSLA 3819
Query 3731 LARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDY 3790
+A+ IV + F ++ I+L Y F+GY CY+G F LLN FR+ +GVY+Y
Sbjct 3820 IAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMGVYNY 3878
Query 3791 LVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLL 3850
+S QE RYMN+ GL PP++S +A LN+KLLGIGG P I+V+ +QSK++DVKC +VVLL
Sbjct 3879 KISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCANVVLL 3938
Query 3851 SVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------I 3904
+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL + AVD I
Sbjct 3939 NCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDTKCLASI 3998
Query 3905 NRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNV 3963
+ + ++ + + LQA+ SEF ++ S+ Y A++ A +G ++ +K+L+K+ N+
Sbjct 3999 DEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNI 4058
Query 3964 AKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALN 4023
AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN
Sbjct 4059 AKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALN 4118
Query 4024 NIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADS 4083
+I++NA GCVPL+ IP A L +V+PD + D TYA ++W IQ V DAD
Sbjct 4119 SILDNAVKGCVPLSAIPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHIQTVQDADG 4178
Query 4084 KIVQLSEINMDNSPNLAWPLIVTALRANS--AVKLQNNELSPVALRQMSCAAGTTQTACT 4141
QL++I++D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4179 INKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDMNCNI 4234
Query 4142 DDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPK 4201
YYNN GR V A+LSD LK+ + K DG + EL+PPC+F KG K
Sbjct 4235 PTQ--CYYNNGSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFSIQDVKGLK 4291
Query 4202 VKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYL 4261
+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VDP K Y DY+
Sbjct 4292 IKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKTYLDYI 4351
Query 4262 ASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCD 4321
GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+ G C
Sbjct 4352 QQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDVDGICK 4411
Query 4322 LKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVC 4381
L+GK+VQ+P DP+ + L + VC VCG W+ CSC + + FLNRV
Sbjct 4412 LRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG--SSVAVQSKDLNFLNRVR 4468
Query 4382 GVSA-ARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFV 4440
G S ARL PC +G STDV RAFDI N AG + K NCCRFQ D++GN LD +FV
Sbjct 4469 GTSVNARLVPCASGLSTDVQLRAFDICNTNRAGIGLYYKVNCCRFQRIDDDGNKLDKFFV 4528
Query 4441 VKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYAL 4500
VKR + Y E+T Y L K C VA HDFF F +DG VPHI R+ L+KYTM DL YAL
Sbjct 4529 VKRTNLEVYNKEKTYYELTKSCGVVAEHDFFTFDIDGSRVPHIVRRNLSKYTMLDLCYAL 4588
Query 4501 RHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQ 4560
RHFD +C L EIL Y C + YF+KKDWYDFVENPDI+ +Y LG ++LL TV
Sbjct 4589 RHFDRNDCSILCEILCEYADCKESYFSKKDWYDFVENPDIINIYKKLGPIFNRALLNTVI 4648
Query 4561 FCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRAL 4620
F D + + G+VGVLTLDNQDL G WYDFGDF+Q APG GV + DSYYS +MP+LT+ L
Sbjct 4649 FADTLVEVGLVGVLTLDNQDLYGQWYDFGDFIQTAPGFGVAVADSYYSYMMPMLTMCHVL 4708
Query 4621 AAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCA 4680
E ++ ++DL++YDFT+ +L LF++YFKYW YHPN ++C +DRCI+HCA
Sbjct 4709 DCELFVNDS----YRQFDLVQYDFTDYKLELFNKYFKYWGMKYHPNTVDCDNDRCIIHCA 4764
Query 4681 NFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKEL 4740
NFN+LFS V P T FGPLVR+IFVDGVPFVVS GYH++ELGVV N DV+ H RLS K+L
Sbjct 4765 NFNILFSMVLPNTCFGPLVRQIFVDGVPFVVSIGYHYKELGVVMNLDVDTHRYRLSLKDL 4824
Query 4741 LVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKE 4800
L+YAADPAMH AS + LLD RT CFSVAA+T+ + FQTVKPGNFN+DFY+F SKG FKE
Sbjct 4825 LLYAADPAMHVASASALLDLRTCCFSVAAITSGIKFQTVKPGNFNQDFYEFVKSKGLFKE 4884
Query 4801 GSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINAN 4860
GS+V+LKHFFF QDGNAAI+DY+YY+YNLPTM DI+QLLFV+EVV KYF+ YDGGCI A+
Sbjct 4885 GSTVDLKHFFFTQDGNAAITDYNYYKYNLPTMVDIKQLLFVLEVVYKYFEIYDGGCIPAS 4944
Query 4861 QVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAK 4920
QVIVNN DKSAG+PFNK+GKARLYY+++S+E+Q+ ++AYTKRNV+PT+TQMNLKYAISAK
Sbjct 4945 QVIVNNYDKSAGYPFNKFGKARLYYEALSFEEQNEIYAYTKRNVLPTLTQMNLKYAISAK 5004
Query 4921 NRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
NRARTVAGVSI STMT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV+
Sbjct 5005 NRARTVAGVSILSTMTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRHLIKDVDN 5064
Query 4981 PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGG 5040
P LMGWDYPKCDRAMPN+LRI++SLVLARKH CC+ RFYRLANECAQVLSE+VMCGG
Sbjct 5065 PVLMGWDYPKCDRAMPNILRIVSSLVLARKHEFCCSHGDRFYRLANECAQVLSEIVMCGG 5124
Query 5041 SLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECL 5100
YVKPGGTSSGDATTA+ANSVFNICQAVTANV +L++ +G+KI D +RNLQ RLY +
Sbjct 5125 CYYVKPGGTSSGDATTAFANSVFNICQAVTANVCSLMACNGHKIEDLSIRNLQKRLYSNV 5184
Query 5101 YRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNN 5160
YR VD+ FV+E+Y +L KHFSMMILSDD VVCYNS+YA++G +A+I F+ VLYYQNN
Sbjct 5185 YRTDYVDYTFVNEYYEFLCKHFSMMILSDDGVVCYNSDYASKGYIANISVFQQVLYYQNN 5244
Query 5161 VFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTD 5220
VFMSE+KCW E D+T GPHEFCSQHTMLVK DYVYLPYPDPSRILGAGCFVDD++KTD
Sbjct 5245 VFMSESKCWVENDITNGPHEFCSQHTMLVKIDGDYVYLPYPDPSRILGAGCFVDDLLKTD 5304
Query 5221 GTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDN 5280
L+IERFVSLAIDAYPL H N+EY VF +YL+YI+KL+++L +LD YSV+L+ +
Sbjct 5305 SVLLIERFVSLAIDAYPLVHHENEEYQKVFRVYLEYIKKLYNDLGTQILDSYSVILSTCD 5364
Query 5281 TSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSH 5340
++ E FY+ MY V+Q+VGACV+C+SQTSLRCG+CIR+P LCCKCCYDHV++T+H
Sbjct 5365 GLKFTEESFYKNMYLKSAVMQSVGACVVCSSQTSLRCGSCIRKPLLCCKCCYDHVMATNH 5424
Query 5341 KLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVG 5400
K VLSV+PYVCNAP CDV+DVT+LYLGGMSYYC++HKP SF L NG VFGLYK +C G
Sbjct 5425 KYVLSVSPYVCNAPNCDVSDVTKLYLGGMSYYCENHKPHYSFKLVMNGMVFGLYKQSCTG 5484
Query 5401 SDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLS 5460
S + DFN IA+C WT DY+LAN C ERLKLFAAET KATEE FK SY AT++E++S
Sbjct 5485 SPYIDDFNKIASCKWTEVDDYVLANECIERLKLFAAETQKATEEAFKQSYASATIQEIVS 5544
Query 5461 DRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKL 5520
DRE+ L WE GK +PPLN+NYVFTGY T K +GEY F+K + + V YR TTTYKL
Sbjct 5545 DREVILCWETGKVKPPLNKNYVFTGYHFTSTGKTVLGEYVFDKSELTNGVYYRATTTYKL 5604
Query 5521 NVGDYFVLTSHTVMPLSAPTLVPQEHY--VRITGLYPTLNISDEFSSNVANYQKVGMQKY 5578
++GD FVLTSH+V LSAPTLVPQE+Y +R + +Y ++ F +NVANYQ +GM++Y
Sbjct 5605 SIGDVFVLTSHSVASLSAPTLVPQENYASIRFSSVY---SVPLVFQNNVANYQHIGMKRY 5661
Query 5579 STLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPAR 5638
T+QGPPGTGKSH AIGLA+YY +AR+VYTA SHAAVDALCEKA K+L I+ C+RIIPA+
Sbjct 5662 CTVQGPPGTGKSHLAIGLAVYYYTARVVYTAASHAAVDALCEKAYKFLNINDCTRIIPAK 5721
Query 5639 ARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYV 5698
RV+C+DKFK+N T +YVF T+NALPE DIVV DE+SM TNY+LSV+NAR++AKHYV
Sbjct 5722 VRVDCYDKFKINDTTCKYVFTTINALPELVTDIVVVDEVSMLTNYELSVINARIKAKHYV 5781
Query 5699 YIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVY 5758
YIGDPAQLPAPR LL+KG+LEP +FNS+ ++M +GPD+FLG C RCP EIV+TVSALVY
Sbjct 5782 YIGDPAQLPAPRVLLSKGSLEPRHFNSITKIMCCLGPDIFLGNCYRCPKEIVETVSALVY 5841
Query 5759 DNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNS 5818
DNKLKA D S+ CFK+++KG TH+ SSA+N QI ++ +FL NP W AVFISPYNS
Sbjct 5842 DNKLKAKNDNSSLCFKVYFKGQTTHESSSAVNIQQIYLISKFLKANPVWNSAVFISPYNS 5901
Query 5819 QNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMS 5878
QN VA ++LG+ TQTVDS+QGSEYDYVI++QT ETAHS NVNRFNVAITRAK GI C+MS
Sbjct 5902 QNYVAKRVLGVQTQTVDSAQGSEYDYVIYSQTAETAHSVNVNRFNVAITRAKKGIFCVMS 5961
Query 5879 DRDLYDKLQFTSLEIPRRNVATL-QAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKT 5937
+ L++ L F +L + + TL + T LFKDCSK G HP AP+ L+VD K+K
Sbjct 5962 NMQLFESLNFITLPLDKIQNQTLPRLHCTTNLFKDCSKSCLGYHPAHAPSFLAVDDKYKV 6021
Query 5938 EG-LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGC 5996
L V++ +TY RLIS+MGFK++ ++GY +FIT++EAI+ VR W+GFDVEG
Sbjct 6022 NENLAVNLNICEPVLTYSRLISLMGFKLDLTLDGYSKLFITKDEAIKRVRGWVGFDVEGA 6081
Query 5997 HATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMY 6056
HATR+ +GTN PLQ+GFSTGV+ V TG + F + AK PPG++FKHLIPLM
Sbjct 6082 HATRENIGTNFPLQIGFSTGVDFVVEATGLFAERDCYTFKKTVAKAPPGEKFKHLIPLMS 6141
Query 6057 KGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRA 6116
KG W++VRI+IVQMLSD L LSD VVF+ W+ FELT ++YF K+G E C +C RA
Sbjct 6142 KGQKWDIVRIRIVQMLSDYLLDLSDSVVFITWSASFELTCLRYFAKLGRELNCNVCSNRA 6201
Query 6117 TCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDA 6176
TC+++ + Y CW HS DYVYNP ++D+QQWG+TG+L SNHD C VH AHVAS DA
Sbjct 6202 TCYNSRTGYYGCWRHSYTCDYVYNPLIVDIQQWGYTGSLTSNHDIICNVHKGAHVASADA 6261
Query 6177 IMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGN 6236
IMTRCLA+++CF K V+W++EYPII +E+ +N++CR +Q +++K+A+L +++ + +DIGN
Sbjct 6262 IMTRCLAIYDCFCKSVNWNLEYPIISNEVSINTSCRLLQRVMLKAAMLCNRYNLCYDIGN 6321
Query 6237 PKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPA 6296
PK + CV + E+KFYDA P A +++LFY Y H D F DG+C+FWNCNVD+YP+
Sbjct 6322 PKGLACVK--DYEFKFYDAFPV---AKSVKQLFYVYDVHKDNFKDGLCMFWNCNVDKYPS 6376
Query 6297 NAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCES 6356
N+IVCRFDTRVL+ LNLPGC+GGSLYVNKHAFHT F ++ F NLK +PFFYYSD+PC
Sbjct 6377 NSIVCRFDTRVLNKLNLPGCNGGSLYVNKHAFHTNPFTRTVFENLKPMPFFYYSDTPCVY 6436
Query 6357 HGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQF 6416
+DYVPL+SATCITRCNLGGAVC HA EY YL++YN++ +AGF+ W+YK F
Sbjct 6437 VDGLESKQVDYVPLRSATCITRCNLGGAVCSKHAEEYCNYLESYNIVTTAGFTFWVYKNF 6496
Query 6417 DTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKT 6476
D YNLWNTFT LQSLENV YN+VN GH+DG GE P +I+N+ V K++ +D IF+N T
Sbjct 6497 DFYNLWNTFTTLQSLENVIYNLVNVGHYDGRTGELPCAIMNDKVVVKINNVDTVIFKNNT 6556
Query 6477 TLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDI 6536
+ P N+A EL+ KR+I+ PE+KIL NL +DI V+WDY +++ ST GVC TD+
Sbjct 6557 SFPTNIAVELFTKRSIRHHPELKILRNLNIDICWKHVLWDYVKDSLFCSSTYGVCKYTDL 6616
Query 6537 AKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTL 6596
+L +LFDGR G ++ FR ARNGV I+ + L+ KGP +A +NGV +
Sbjct 6617 ------KFIENLNILFDGRDTGALEAFRKARNGVFISTEKLSRLSMIKGPQRADLNGVIV 6670
Query 6597 --IGE-SVKTQFNYFKKVDGIIQQLPE-------------------------------TY 6622
+GE V+ F K D +I + T
Sbjct 6671 DKVGELKVEFWFAMRKDGDDVIFSRTDSLCSSHYWSPQGNLGGNCAGNVIGNDALTRFTI 6730
Query 6623 FTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIG 6682
FTQSR L F+PRS +E DF+++ + FI +Y LE YAF+HIVYG F+H +GGLHL+IG
Sbjct 6731 FTQSRVLSSFEPRSDLERDFIDMDDNLFIAKYGLEDYAFDHIVYGSFNHKVIGGLHLLIG 6790
Query 6683 LAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSV 6742
L +R + S L +++F+ DS++ +YFITD + GSSK VC+VIDLLLDDFV I+KS +LS
Sbjct 6791 LFRRKKKSNLLIQEFLQYDSSIHSYFITDQECGSSKSVCTVIDLLLDDFVSIVKSLNLSC 6850
Query 6743 ISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDL 6802
+SKVV + +D+ + FMLWC D + TFYPK+QA+ W+PG +MP LYK + LE+ L
Sbjct 6851 VSKVVNINVDFKDFQFMLWCNDNKIMTFYPKMQATNDWKPGYSMPVLYKYLNVPLERVSL 6910
Query 6803 QNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQ 6862
NYG+ +P G MMNVAKYTQLCQYLNT TLAVP NMRV+H GAGSDK VAPG+AVLRQ
Sbjct 6911 WNYGKPINLPTGCMMNVAKYTQLCQYLNTTTLAVPVNMRVLHLGAGSDKEVAPGSAVLRQ 6970
Query 6863 WLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKE 6922
WLP+G++LVD+DLN FVSD+ T GDC T+ WDLIISDMYDP TK++ N SK+
Sbjct 6971 WLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPFDCHWDLIISDMYDPLTKNIGDYNVSKD 7030
Query 6923 GFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLI 6982
GFFTY+C I+ KL+LGGS+A+KITE SWNADLYKLM F++WT F TNVNASSSE FLI
Sbjct 7031 GFFTYICHLIRDKLSLGGSVAIKITEFSWNADLYKLMSCFAFWTVFCTNVNASSSEGFLI 7090
Query 6983 GANYLGKPKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQI 7042
G NYLGK +IDG MHANY+FWRN+ +YSLFDM+KF LKL GTAV++L+ +Q+
Sbjct 7091 GINYLGKSSFEIDGNVMHANYLFWRNSTTWNGGAYSLFDMTKFSLKLAGTAVVNLRPDQL 7150
Query 7043 NDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
ND++YSL+E+G+L++R+ + + D LVN
Sbjct 7151 NDLVYSLIERGKLLVRDTRKEIFVGDSLVNT 7181
Score = 301 bits (770), Expect = 2e-79, Method: Composition-based stats.
Identities = 160/939 (17%), Positives = 315/939 (34%), Gaps = 166/939 (18%)
Query 141 KSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPLDC 200
+D D D + K+ A L R+ G +VD C G DC
Sbjct 185 FKFDDYDFSVEDAYAEVHAEPKGKYSQKAYA-LLRQYRGIKPVLFVDQYGCDYSGKLADC 243
Query 201 IKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKS 259
A S+ + ++ + +AW R + QT I
Sbjct 244 ---LQAYGHYSLQDMRQKQSVWLANCDFDIV------VAWHVVRDSRFVMRLQTIATICG 294
Query 260 AK-----KFDTFKGEC----PKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQ 310
K D G+ P + ++ V + P + K T I+S+Y V
Sbjct 295 IKYVAQPTEDVVDGDVVIREPVHLLSADAIVLKL-PSLMKVMTHMDDFSIKSIYNVD-LC 352
Query 311 ECNNMHLSTLMKC--NHCDEVSWQTCDFLKATCE-HCGTENLVIEG-PTTCGYLPTNAVV 366
+C + + C ++CD W + + + C T E + G +P N V+
Sbjct 353 DCGFVMQYGYVDCFNDNCDFYGWVSGNMMDGFSCPLCCTVYDSSEVKAQSSGVIPENPVL 412
Query 367 KMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPR 426
+ H + + +S FG C++ + W+P
Sbjct 413 FT------NSTDTVNHDSFNLYGYSVTP-----------FGSCIY----WSPRPGLWIPI 451
Query 427 ASADI-------GSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILAS 479
+ + SG G ET L + G+ N +
Sbjct 452 IKSSVKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQCK---CGNLEQNHIL------ 502
Query 480 FSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQ 539
++ + ++ + G+Y + NI F +
Sbjct 503 -------------GVNNSWCRQLLLNRGDYNMLLK-------NIDLFVKRRA---DFACK 539
Query 540 AAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYT-------SDLLT 592
A + +LDG+ +S L+ + ++ S ++
Sbjct 540 FA-----VCGDGF-------------VPFLLDGLIPRSYYLIQSGIFFTSLMSQFSQEVS 581
Query 593 NSVIIMAYVTGGLVQQTSQWLSNLLGTTVEK--------LRPIFEWIEAKLSAGVEFLKD 644
+ + M + V + ++ + + V + + + W L A
Sbjct 582 DMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDASAP--AT 639
Query 645 AWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAK----L 700
W + + L+ G+F + + + I D K ++ ++ ++ VT+ K L
Sbjct 640 GWLLYQ-LLNGLFVVSQANFNFVA-LIPDYAKILVNKFYTFFKLLLECVTVDVLKDMPVL 697
Query 701 RSLNL-----GEVFIAQSKGLYRQCIRGKEQLQLLMPLKA-PKEVTFLEGDSHDTVLTSE 754
+++N G F S GL ++P A +++ F EG +E
Sbjct 698 KTINGLVCIVGNKFYNVSTGLI---------PGFVLPCNAQEQQIYFFEG-------VAE 741
Query 755 EVVLKNGELEALETPVDSFT---NGAIVGTPVCVNGLMLLEIKDKEQYCALSP-GLLATN 810
V++++ +E +++ + S+ V ++ + + + DK ++ + +
Sbjct 742 SVIVEDDVIENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGDKFFPIVMNDKNICLLD 801
Query 811 NVFRLKGGAPIKGVTFGED-TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEV 869
+R + V F E V E+ V++ F+LD D +L + CS + VE G V
Sbjct 802 QAWRFPCAG--RKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILGKVCSEFEVEKGVTV 859
Query 870 TEFACVVAEAVVKTLQPVSD---LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFY 926
+F VV +A+ L + + + L++ + YLFD+AG+E +SRMYC+F
Sbjct 860 DDFVAVVCDAIENALNSCKEHPVVGYQVRAFLNKLNENVVYLFDEAGDEAMASRMYCTFA 919
Query 927 PPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTT 986
D E+ +E E+ ID E ++D + E V + ++ED +
Sbjct 920 IEDVEDVISSEAVEDTIDGVVEDTINDDEDVVTGDND----DEDVVTGDNDDEDVVTGDN 975
Query 987 EQSEIEP---EPEPTPEEPVNQFTGYLKLTDNVAIKCVD 1022
+ ++ + E + D+ + D
Sbjct 976 DDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGD 1014
Score = 172 bits (437), Expect = 1e-40, Method: Composition-based stats.
Identities = 55/162 (34%), Positives = 79/162 (49%), Gaps = 2/162 (1%)
Query 1005 QFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKE 1064
L +T NV DI+ A+ VIVN AN H+ HGGGVA A+ A KE
Sbjct 1353 PQLYGLCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKE 1412
Query 1065 SDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDIL 1122
+ +K G VG + +G L K L++VGP+ + LL AY++ N+ D
Sbjct 1413 TAAMVKSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCC 1472
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
L+ L+SAGIF SL + V QV + N+K ++ +
Sbjct 1473 LSTLISAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDII 1514
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 25/157 (16%), Positives = 44/157 (28%), Gaps = 15/157 (10%)
Query 1194 EKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMS 1253
+V D+ + +V +L + + + E +
Sbjct 1361 TPNVCFVKGDIINVARLVKADVIVNPANGH-----MLHGGGVAKAIAVAAGKKFSKETAA 1415
Query 1254 FLEKDAPYMVGDVITSGD------ITCVVIPSKKAGGTTE--MLSRALKKVPVDEYITTY 1305
++ VGD S I +V P + G +L+RA K ++ Y
Sbjct 1416 MVKSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKH--LNNYDCCL 1473
Query 1306 PGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEE 1342
AG A +L N KE+
Sbjct 1474 STLISAGIFSVPADVSLTYLLGVVDKQVILVSNNKED 1510
Score = 49.3 bits (116), Expect = 0.002, Method: Composition-based stats.
Identities = 46/205 (22%), Positives = 76/205 (37%), Gaps = 18/205 (9%)
Query 1573 PTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTL----DESFLGRYMSALN 1628
+ +I N + DD F+ Y L D ++S +
Sbjct 1079 DVVTGDNNDEEIVTGDNDDQIVVTGDDVDDIESIYDFDTYKALLVFNDVYNDALFVSYGS 1138
Query 1629 HTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFC 1688
+ + +V GL S NC+L SVLL +Q+L KF A++ + + G +F
Sbjct 1139 SVETETYFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFV 1198
Query 1689 ALILAYSNKTVGEL--GDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVM 1746
+L K + G V + L ++ N C CG + L G++A+
Sbjct 1199 DYLLTTIPKAIVLPQGGFVADFAYWFLNQFDI---NAYANWCCLKCGF-SFDLNGLDALF 1254
Query 1747 YMGTLSYDNLKTGVSIPCVCGRDAT 1771
+ G + VS C CG + T
Sbjct 1255 FYGDI--------VSHVCKCGHNMT 1271
>sp|P0C6W0|R1AB_BC512 Replicase polyprotein 1ab OS=Bat coronavirus
512/2005 OX=693999 GN=rep PE=3 SV=1
Length=6793
Score = 6828 bits (17715), Expect = 0.0, Method: Composition-based stats.
Identities = 2302/5093 (45%), Positives = 3170/5093 (62%), Gaps = 173/5093 (3%)
Query 2012 GMDNLACESQQPTSEEVVE-NPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHE 2070
G+D+ C P + VV N T+ + V +L
Sbjct 1841 GLDDGNCVHGLPLVDRVVSVNGTVIITNVGDTPGKPVVATENLLLDGVSYTVFQDSTTGV 1900
Query 2071 DLMAAYVENTSIT----IKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQA 2126
+ + + + KP +L+++ + + + P ++ FL
Sbjct 1901 GHYTVFDKEAKLMFDGDVLKPCDLNVSPVTSVVVCNNKKIVVQDPVKRVELDASKFLDTM 1960
Query 2127 AITTSNCAKRL--AQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPT---TIAKNSVK 2181
+ + R + Y+F+LL K + ++ A +P I K SVK
Sbjct 1961 NVASEKFFTFGDFVSRNIIVLIVYLFSLLAICFRALKKRDMKVMAGVPERTGIILKRSVK 2020
Query 2182 SVAKLCLDAGINYVKSPKFSKL-FTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYC 2240
NY F +L F L S+ L +L + F + + G P C
Sbjct 2021 ----------YNYKALKFFFRLKFQYIKVFLKFSLVLYTLYALMFMF-IRFTPVGTP-IC 2068
Query 2241 NGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGL 2300
+ Y NS+ D+C C ICL G + L + I + L IL L
Sbjct 2069 KRYTDGYANST-FDKNDYCGN-VLCKICLYGYEELSDFTHTRVIWQHLKD-PLIGNILPL 2125
Query 2301 AAEWVLAYMLFTKFFYLLGLSAIMQVFF--GYFASHFISNSWLMWFIISIVQMAPVSAMV 2358
+++ ++F FF +G++ + + A + N WL+ + P ++M
Sbjct 2126 F--YLVFLIIFGGFFVRIGITYFIMQYINAAGVALGYQDNVWLL-------HLLPFNSMG 2176
Query 2359 RMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGG 2418
+ + I H++ GC +C+ C K + TRV TI+ G+ +SFYV ANGG
Sbjct 2177 NIIVVAFIVTRILLFLKHVLFGCDKPSCIACSKSAKLTRVPLQTILQGVTKSFYVNANGG 2236
Query 2419 RGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGAL 2478
+ FCK HN+ C++CD++ G TFI+D +A +LS K + PT ++ I+D V NG
Sbjct 2237 KKFCKKHNFFCVDCDSYGYGCTFINDVIAPELSNVTKLNVIPTGPATIIIDKVEFSNGFY 2296
Query 2479 HLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYY 2538
+LY K + + D L+ N + + +VF+ S + + K+A VY+
Sbjct 2297 YLYSGSTFWKYNFDITEAKYACKDVLKNCN----ILTDFVVFNN-SGSNVTQVKNACVYF 2351
Query 2539 SQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELA 2598
SQL+C+PI L+D AL++ + + S + A+V+ S +F + +
Sbjct 2352 SQLLCKPIKLVDSALLASLN--VDFSANLHKAFVEVLSNSFGKDLSNCSNM--------- 2400
Query 2599 KGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVE 2658
+ R+ + +DV ++ + +H D+ ++ S NN +++Y K E
Sbjct 2401 -------------NECRESLGLSDVPEEEFSAAVSEAHRYDVLISDVSFNNLIVSYAKPE 2447
Query 2659 -NMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPF 2717
+ D+ C+ A+ +N V NV ++W KD+++LSE+ RK I K I F
Sbjct 2448 EKLAVHDIANCMRVGAKVVNHNVLTKDNVPVVWLAKDFIALSEEARKYIVRTTKTKGINF 2507
Query 2718 RLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHD 2777
LT R + + T ++ K G + + F + + L L+ + + L
Sbjct 2508 MLTFNDRRMHLTIPTISVANKKGAGLPSLFTRLY--SFFWHLCVLIVVLFVATSLLDFSA 2565
Query 2778 GYTNEI-IGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGS-YKNDKSCPVVAAII 2835
T++ +K I++GV + DC N F+ W + + GS N + CP+V
Sbjct 2566 QVTSDTQYDFKYIENGVLKVFEKPLDCVHNAFVNFNEWHNAKFGSIPTNSRRCPIVVGTS 2625
Query 2836 TREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAE 2895
+PG+P V + G L F +C+ L + +C+ +
Sbjct 2626 DEV--RYIPGVPAGVF--LYGKSLIFAMSTIFGTSGLCFDDRGLTD-----PDSCIFNSA 2676
Query 2896 CTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEG-SVRVVT 2954
CT G+ V YCY +++ + YS L P + Y LMDG+ I P G +R +
Sbjct 2677 CTTLSGIGGRNV-YCYREGVVDNAKLYSSLLPHSYYRLMDGNHIVLPEIITRGFGIRTIK 2735
Query 2955 TFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQP 3014
T YCR G C S+ G+C+ +V + S CG +L+ N+
Sbjct 2736 TQAMTYCRTGECIDSQAGVCVGLDRFFVYSKT---PGSDYVCGTGFFSLLFNVIGMFSNS 2792
Query 3015 VGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPA 3074
+ +S ++ ++A A + F KF+R+FG+ + V + L +++ +V
Sbjct 2793 IPVTVMSGQILLNCVVAFTAVMACFAFTKFKRLFGDMSFGVLSVGLCTVVNNL-SYVVTQ 2851
Query 3075 YSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFF 3134
S Y+ Y T S++ H+ + + + P+W+ Y+ C L+ F
Sbjct 2852 NSIGMLAYATLYFLCTK--GVRYSWVWHVGFAISYCFLAPWWVVLAYLICALLEFLPNLF 2909
Query 3135 NNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKY 3193
+ + +F G F +FE AA TF+L+ Y KL + + + +Y A YN+YKY
Sbjct 2910 KLKVSTQ-LFEGDKFVGSFESAASGTFVLDMHSYQKLANS--ISTEKLKQYCASYNRYKY 2966
Query 3194 FSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKV 3253
+SG+ YR A HLAKA++DF+N D LY PP S S LQ+G RKMA PSG V
Sbjct 2967 YSGSASEADYRLACFAHLAKAMSDFANDHMDKLYTPPTVSYNST-LQAGLRKMAQPSGIV 3025
Query 3254 EGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNV 3313
EGC+V+V+ G TLNGLWL DTV CPRHVI + + +Y+ + H+F + +GN+
Sbjct 3026 EGCIVRVSYGNLTLNGLWLGDTVICPRHVIASNTTNV-IDYDHAMSLVRLHNFSISSGNM 3084
Query 3314 QLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN 3373
L VI SM+ LL +KV+ SN TP Y + ++PG +F++LACY+GS +GVY MR N
Sbjct 3085 FLGVISASMRGTLLHIKVNQSNVNTPNYTYKVLKPGDSFNILACYDGSAAGVYGVNMRTN 3144
Query 3374 HTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQA 3433
+TI+GSF++G+CGS G+NI+ V FCYMHH+EL +G H G+D++G YG + D+ T Q
Sbjct 3145 YTIRGSFISGACGSPGYNINNGVVEFCYMHHLELGSGCHVGSDMDGTMYGKYEDQPTLQI 3204
Query 3434 AGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPL 3493
G +T NV +WLY A+INGDRW+L+ + ++ +N A++ L +VD L
Sbjct 3205 EGASNLVTENVCSWLYGALINGDRWWLSSVSVGVDTYNEWALRNGMTALK--NVDCFSLL 3262
Query 3494 SAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ-GKFKKI 3552
A+TG+ V + A++++L N G++ILG T L DEFT +VV+Q GVT Q GK +
Sbjct 3263 VAKTGVDVGRLLASIQKLHGN-FGGKSILGCTSLCDEFTLSEVVKQMYGVTLQSGKVSRA 3321
Query 3553 VKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAF 3612
+ L FL L + S F++ P L I+ ++ MLLVKHK F
Sbjct 3322 FRNASIVCCLLFLF----LSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLF 3377
Query 3613 LCLFLLPSLATVAYFNMV--YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLI 3670
L L+LLPSL V+ +N+ Y ++++ + G+ + + + ++
Sbjct 3378 LQLYLLPSLCIVSGYNIFKDYHFYTYMLEEFDY----KVPFGGFNVTGVLNISLCCFVMG 3433
Query 3671 LMTARTVYDDAARRVW-TLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIM 3729
L T R + +++ ++ V+T++Y YY + + +S +NY + T
Sbjct 3434 LHTFR--FLQTPNKIFSYVVAVLTVLYTYYYS---TDVLGLILTSMSGFTNYWFIGTATY 3488
Query 3730 FLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYD 3789
LA V + L + + ++ ++ +Y LGYC C Y+G +NR+ +LTLG Y+
Sbjct 3489 KLATY-----VLPHTSLLDSFDAIKAVVFLYLLLGYCNCVYYGSLYWINRFCKLTLGCYE 3543
Query 3790 YLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVL 3849
+ VS EF+YM + GL P DA L++KL+G+GG+ IK+++VQSK++D+KCT+VVL
Sbjct 3544 FKVSAAEFKYMVANGLRAPTGVFDALILSLKLIGVGGRKTIKISSVQSKLTDLKCTNVVL 3603
Query 3850 LSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCE 3909
L L + + ++S+ WA CV LHN I L D A E +++LL+ LS A ++ L +
Sbjct 3604 LGCLSNMNIAANSREWAYCVDLHNKINLCNDAEAAQEMLLALLAFFLSKNSAFGVDELLD 3663
Query 3910 EMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFD 3969
++ + LQ++A+ + +LPSY AY TA+++YE A+ANG ++K+L+ ++NVAKSEFD
Sbjct 3664 SYFNDSSVLQSVAATYVNLPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFD 3723
Query 3970 RDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNA 4029
R+A+ QRKL++MA+QA +QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I++ A
Sbjct 3724 REASTQRKLDRMAEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLA 3783
Query 4030 RDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLS 4089
+DG VPL+IIP +A KL +VV D +Y YA +W + + D D K V
Sbjct 3784 KDGVVPLSIIPAVSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAK 3843
Query 4090 EINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYY 4149
E+ N +LAWPL + R +KLQNNE+ P ++Q A D NAL Y
Sbjct 3844 EVVTSNVESLAWPLFLNCER---IIKLQNNEIIPSKIKQRPIKAEGE-GVVADGNAL--Y 3897
Query 4150 NNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIK 4209
+N G F+ A +SD DLK ++ G+ I ELEPPC+F+ + P GP VKYLYF++
Sbjct 3898 SNEGGRTFMYAFISDKPDLKVVKWEFDGGSNAI--ELEPPCKFLVEAPSGPVVKYLYFVR 3955
Query 4210 GLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPIT 4269
LNNL RG VLG + ATVRLQAG TE NS++L+ CAFAVDP K Y D + SG +P+
Sbjct 3956 NLNNLRRGAVLGFIGATVRLQAGKQTEQATNSSLLTLCAFAVDPPKTYLDAVKSGHRPVG 4015
Query 4270 NCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQI 4329
NCVKML +G GQAIT EA+ +Q+S+GGAS CLYCR H++HP+ GFC L+GKYVQ+
Sbjct 4016 NCVKMLANGSGNGQAITNGVEASTNQDSYGGASVCLYCRAHVEHPDMDGFCKLRGKYVQV 4075
Query 4330 PTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLT 4389
P DP+ F L NTVC VCG W+ GC+CD+ ++QS D S +LNRV G SAARL
Sbjct 4076 PLGTL-DPIRFVLENTVCKVCGCWQANGCTCDR---AVIQSVD-SGYLNRVRGSSAARLE 4130
Query 4390 PCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNY 4449
P G+ T V+RAFD+YN VA +KFLK NC R + D+ D++++VK+ T S
Sbjct 4131 PL-NGSDTHHVFRAFDVYNRDVACISKFLKVNCVRLKNLDKH----DAFWIVKKCTKSVM 4185
Query 4450 QHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCD 4509
+HE++IYNL+ DC AVA HDFF ++ + ++ RQ LT+YTM DL YALR+FDE NC+
Sbjct 4186 EHEQSIYNLISDCGAVAKHDFFTWKEGRSVYGNVCRQDLTEYTMMDLCYALRNFDENNCE 4245
Query 4510 TLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAG 4569
TLK+ILV CD+ YF+ K W+D VEN D+ RVYA LG V +++LK V++CDAM + G
Sbjct 4246 TLKKILVVVGACDESYFDNKLWFDPVENEDVHRVYAKLGTIVARAMLKCVKYCDAMVEQG 4305
Query 4570 IVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDAD 4629
IVGV+TLDNQDLNG++YDFGDFV G GVPI SYYS +MP++ +T LA+E + +D
Sbjct 4306 IVGVITLDNQDLNGDFYDFGDFVTSVKGMGVPICTSYYSYMMPVMGMTNCLASECFIKSD 4365
Query 4630 L-AKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFST 4688
+ + +DLL YDFTE ++ LF++YFK+W QTYHPNC +C D+ CI+HCANFN LF+T
Sbjct 4366 IFGEDFRTFDLLAYDFTEHKVNLFNKYFKHWGQTYHPNCEDCHDESCIVHCANFNTLFAT 4425
Query 4689 VFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPA 4748
P T+FGPL RK ++DGVP V + GYHF++LG+V N+D+NLHSSRL+ ELL + ADP+
Sbjct 4426 TIPITAFGPLCRKCWIDGVPLVTTAGYHFKQLGIVWNKDLNLHSSRLTINELLQFCADPS 4485
Query 4749 MHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKH 4808
+ AS L+DKRT CFSVAAL + QTVKPG+FN++FYDF S+GFF+EGS + LKH
Sbjct 4486 LLIASSPALVDKRTVCFSVAALGTGMTNQTVKPGHFNREFYDFLRSQGFFEEGSELTLKH 4545
Query 4809 FFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLD 4868
FFFAQ G+AA+ D+DYYRYN T+ DI Q V ++V YF Y+GGCI A +VIVNNL+
Sbjct 4546 FFFAQKGDAAVRDFDYYRYNRTTVLDICQARVVYQIVQCYFGMYEGGCITAKEVIVNNLN 4605
Query 4869 KSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAG 4928
KSAG+PFNK+GKA LYYDS+SYE+QD L+AYTKRN+IPT+TQ+NLKYAIS K+RARTV G
Sbjct 4606 KSAGYPFNKFGKAGLYYDSLSYEEQDDLYAYTKRNIIPTMTQLNLKYAISGKDRARTVGG 4665
Query 4929 VSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDY 4988
VS+ STMT RQ+HQK LKSI TRGA+VVIGT+KFYGGW NMLKT+ DVE PHLMGWDY
Sbjct 4666 VSLLSTMTTRQYHQKHLKSIVNTRGASVVIGTTKFYGGWDNMLKTLIKDVENPHLMGWDY 4725
Query 4989 PKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGG 5048
PKCDRA+PNM+R++++++L KH CC+ S R+YRL NE AQVL+EMV G YVKPGG
Sbjct 4726 PKCDRALPNMIRMISAMILGSKHVNCCSSSDRYYRLCNELAQVLTEMVYSNGGFYVKPGG 4785
Query 5049 TSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDH 5108
T+SGDATTAYANSVFNI QA +ANVN LLS D N + V+ LQ +LY+C YR+ VD
Sbjct 4786 TTSGDATTAYANSVFNIFQATSANVNRLLSVDSNTCNNIEVKQLQRKLYDCCYRSSSVDQ 4845
Query 5109 EFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKC 5168
FV+E++ YLRKHFSMMILSDD VVCYNS YAA G VA + FKAVLYYQNNVFMS +KC
Sbjct 4846 SFVEEYFGYLRKHFSMMILSDDGVVCYNSEYAALGYVADLNAFKAVLYYQNNVFMSASKC 4905
Query 5169 WTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERF 5228
W E D+ KGPHEFCSQHTM + D YLPYPDPSRIL AG FVDDIVKTD +++ER+
Sbjct 4906 WIEPDINKGPHEFCSQHTMQIVDKDGTYYLPYPDPSRILSAGVFVDDIVKTDPVILLERY 4965
Query 5229 VSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPE 5288
VSLAIDAYPL+KH N EY VF + L +++ L+ L +LD +SV L D T+++W+
Sbjct 4966 VSLAIDAYPLSKHDNPEYRRVFTVMLDWVKHLYKTLNQGVLDSFSVTLLEDATAKFWDES 5025
Query 5289 FYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNP 5348
FY +MY +VLQ+ G CV+C+SQT LRCG CIRRP LC KC YDHV+STSHK +L++ P
Sbjct 5026 FYASMYEQSSVLQSAGLCVVCSSQTVLRCGDCIRRPMLCTKCAYDHVVSTSHKFILAITP 5085
Query 5349 YVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFN 5408
YVC + GC V+DVT+LYLGG+SY+C HKP +SFPLC++G VFGLYKN+ GS +V DFN
Sbjct 5086 YVCCSSGCGVSDVTKLYLGGLSYWCVDHKPRLSFPLCSSGNVFGLYKNSATGSPDVDDFN 5145
Query 5409 AIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSW 5468
+AT DWT+ DY LAN + L+LFAAET+KA EE+ K SY AT+ EV+ +EL L W
Sbjct 5146 TLATSDWTDVKDYKLANDVKDSLRLFAAETIKAKEESVKSSYACATIHEVVGPKELVLKW 5205
Query 5469 EVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDY-GDAVVYRGTTTYKLNVGDYFV 5527
EVGKPRPPL+RN VFT Y +TKN+K Q+GE+TFEK DY DAV Y+ T T KL G FV
Sbjct 5206 EVGKPRPPLSRNSVFTCYHITKNTKFQVGEFTFEKLDYDNDAVSYKSTATTKLVPGMVFV 5265
Query 5528 LTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGT 5587
LTSH V PL APT++ QE Y + L P NI +++S+ + YQ +G QK +T+QGPPG+
Sbjct 5266 LTSHNVQPLRAPTIINQERYSTLHKLRPAFNIHEDYSNLIPYYQLIGKQKLTTIQGPPGS 5325
Query 5588 GKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKF 5647
GKSH IGL LY+P ARIV+TACSHAAVD+LC KA D+CSRIIP +AR+EC+D F
Sbjct 5326 GKSHCVIGLGLYFPGARIVFTACSHAAVDSLCVKAATAYSSDRCSRIIPQKARIECYDGF 5385
Query 5648 KVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLP 5707
K N+T QY+F TVNALPE ADI V DE+SM TNYDLSV+N R+ +H VY+GDP QLP
Sbjct 5386 KSNNTSAQYLFSTVNALPEVNADICVVDEVSMCTNYDLSVINQRVNYRHIVYVGDPQQLP 5445
Query 5708 APRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD 5767
APR ++T+G L PE +N V R M + PD+FL C RCPAEIV+TVS +VY+N+ K
Sbjct 5446 APRVMITRGVLVPEDYNVVTRRMCVLKPDIFLHKCYRCPAEIVNTVSEMVYENQFVPVKS 5505
Query 5768 KSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL 5827
+S +CFK++ +G + D S+INR Q+ VVR FL +NP W KAVFISPYNSQN VA ++L
Sbjct 5506 ESKECFKIYCRGNVQVDNGSSINRRQLEVVRMFLAKNPKWAKAVFISPYNSQNYVAGRVL 5565
Query 5828 GLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQ 5887
GL QTVDSSQGSEYDYVI+TQT++TAH+ NVNRFNVAITRAK GILCIM DR+L+D L+
Sbjct 5566 GLQIQTVDSSQGSEYDYVIYTQTSDTAHASNVNRFNVAITRAKKGILCIMCDRELFDILK 5625
Query 5888 FTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGI 5947
F L++ + LQ + GLFKDC K L P+ APT +S+ FKT+ G+
Sbjct 5626 FYELKL-----SDLQVGDGCGLFKDCYKGEDNLPPSHAPTFMSLSDNFKTDKDLAVQIGV 5680
Query 5948 PKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNL 6007
+ Y +IS MGF+ + V +F TR+ A+R+ R W+GFDVEG H VGTN+
Sbjct 5681 NGPVKYEHVISFMGFRFDINVPNQHTLFCTRDFAMRNARGWLGFDVEGAHVIGSNVGTNV 5740
Query 6008 PLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIK 6067
PLQLGFS GV+ V P G V TE V A+ PPGDQF HL+PL+ KG PW+V+R +
Sbjct 5741 PLQLGFSNGVDFVVRPEGCVSTEVGDVIQPVRARAPPGDQFTHLLPLLRKGQPWSVIRRR 5800
Query 6068 IVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYA 6127
IVQM SD L LSD ++FVLW+ G ELT+M+YFVK+GP +TC C KRATC+++++ T++
Sbjct 5801 IVQMCSDYLANLSDTLIFVLWSGGLELTTMRYFVKLGPVQTC-DCGKRATCYNSTNHTFS 5859
Query 6128 CWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHEC 6187
C+ H++G DY+YN + ID+QQWG+TG+L NH + C +H N HVAS DA MTRCLA+H+C
Sbjct 5860 CFRHALGSDYIYNCYCIDIQQWGYTGSLSMNHHEVCNIHRNEHVASGDAAMTRCLAIHDC 5919
Query 6188 FVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAE 6247
FVK VDWS+ YP I +E +N + R VQ V+++ L +HD+GNPK I+CV +
Sbjct 5920 FVKNVDWSITYPFIANEQAINKSGRLVQSHVMRAVLKLYNPKAIHDVGNPKGIRCV-VTD 5978
Query 6248 VEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRV 6307
W YD P + +E Y Y TH DG+CLFWNCNVD YP ++VCRFDTR+
Sbjct 5979 ASWYCYDKNPTNTNVKMLE---YDYITHGQ--LDGLCLFWNCNVDMYPEFSVVCRFDTRM 6033
Query 6308 LSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDY 6367
S LNL GC+GGSLYVN HAFHTPA+DK AF LK +PFF+Y DS CE ++ ++Y
Sbjct 6034 RSTLNLEGCNGGSLYVNNHAFHTPAYDKRAFAKLKAMPFFFYDDSECE----KLQDAVNY 6089
Query 6368 VPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTF-- 6425
VPL+++ CITRCN+GGAVC H Y Y+ AYN +AGF++W+ FD +NLW TF
Sbjct 6090 VPLRASNCITRCNVGGAVCSKHCALYHNYVMAYNTFTTAGFTIWVPNSFDMFNLWQTFKN 6149
Query 6426 TRLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFE 6485
+ +Q LEN+AYNVV KG F G GE PV+++N+ V + D +F N T+LP NVAFE
Sbjct 6150 SNVQGLENIAYNVVKKGSFVGVEGELPVAVVNDKVMVRDGVSDNVVFVNNTSLPTNVAFE 6209
Query 6486 LWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESAC 6545
L+AKR + P + IL NLGV + V+WDY+ P T VC TD
Sbjct 6210 LYAKRKVGLTPPLTILKNLGVVCTSKCVLWDYEASRPLTTFTKDVCKYTDFD-------- 6261
Query 6546 SSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVK--T 6603
+ LFD V G + F +N VLI+ +VK LT K +NGV + K T
Sbjct 6262 GDVCTLFDNSVPGAFERFTVTKNAVLISLTAVKKLTAIK-LTYGYLNGVPVFTHEDKPFT 6320
Query 6604 QFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEH 6663
+ Y +K DG + P+ YFTQ R + DF+PRS ME DFL + M FI +Y LE Y FEH
Sbjct 6321 WYIYTRK-DGAFVEYPDGYFTQGRVISDFQPRSNMEEDFLNMDMGLFISKYGLEDYGFEH 6379
Query 6664 IVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFI-PMDSTVKNYFITDAQTGSSKCVCS 6722
+V+GD S LGGLHL+I + S+ LK+EDF+ DST+K+ +T SSK VC+
Sbjct 6380 VVFGDVSKTTLGGLHLLISQIRLSKIGVLKVEDFVSSSDSTLKSCTVTYVDNPSSKMVCT 6439
Query 6723 VIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQP 6782
+DLLLDDFV I+KS DLSV+SKV +V ID +MLWCKD V+TFYP+LQ+++ W+
Sbjct 6440 YVDLLLDDFVNILKSVDLSVVSKVHEVVIDCKVWRWMLWCKDHKVQTFYPQLQSAE-WKC 6498
Query 6783 GVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRV 6842
G +MP++YK+QRM LE C+L NYG +P GIM NV KYTQLCQYLN+ T+ VP++MRV
Sbjct 6499 GYSMPSIYKIQRMCLEPCNLYNYGSGLKLPDGIMFNVVKYTQLCQYLNSTTMCVPHHMRV 6558
Query 6843 IHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLI 6902
+H GAGSDKGVAPGTAVLR+WLP ++VD+D+ND+VSDAD + GDCA+++ +K+DL+
Sbjct 6559 LHLGAGSDKGVAPGTAVLRRWLPLDAVIVDNDVNDYVSDADFSYTGDCASMYLTDKFDLV 6618
Query 6903 ISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHF 6962
ISDMYD RTK +N SKEGFF Y+ G I +KLALGG++A+KITE SWN LY+L+ F
Sbjct 6619 ISDMYDGRTKSCDGDNVSKEGFFPYINGVITEKLALGGTVAIKITEFSWNKKLYELIQKF 6678
Query 6963 SWWTAFVTNVNASSSEAFLIGANYLGKP--KEQIDGYTMHANYIFWRNTNPIQLSSYSLF 7020
+WT F T+VN SSSEAFLIG ++LG IDG MHANYIFWRN+ + +S S+
Sbjct 6679 EYWTLFCTSVNTSSSEAFLIGVHFLGDFSTNAIIDGNIMHANYIFWRNSTIMTMSYNSVL 6738
Query 7021 DMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
D+SKF K + T V++LK++ + D++ LL+ G+L+IR N V S+ LVN+
Sbjct 6739 DLSKFSCKHKATVVVNLKDSSVTDLVLGLLKNGKLLIRNNGVVCGFSNHLVNS 6791
Score = 268 bits (686), Expect = 1e-69, Method: Composition-based stats.
Identities = 83/361 (23%), Positives = 132/361 (37%), Gaps = 38/361 (11%)
Query 1538 SLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFV 1597
+L E K ++V T D + HT + S TYGQQ G ++ VT +KP + V
Sbjct 1634 TLFEAKPVQVVVTQDQRSFHTVELSTSQTYGQQLGDCVVEDKKVTNLKPVSKDK--VVSV 1691
Query 1598 LPSDDTLRSEAF---EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLS 1654
+P+ D + F +HTLD + + V G ++ +DNNC+++
Sbjct 1692 VPNVDWDKHYGFVDAGIFHTLDHTMFVFDNN-----------VVNGKRVLRTSDNNCWIN 1740
Query 1655 SVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQ 1714
+V L LQ KF LQ+ + GD A F + + GE D T+ + +
Sbjct 1741 AVCLQLQFANAKFKPKGLQQLWESYCTGDVAMFVHWLYWITGVEKGEPSDAENTLNIISR 1800
Query 1715 HANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIP-CVCGRDATQY 1773
+ + +L C +T + V+ ++ LK G+ CV G
Sbjct 1801 FLKPQGSVEMLRATSTTCDGTCST----KRVVSTPVVNASVLKVGLDDGNCVHGLPLVDR 1856
Query 1774 LVQQESSFVMMSA---PPAEYKLQQGTFLCANEYT----GNYQCGHYTHITAKETLYRID 1826
+V + ++ + P + L YT GHYT + KE D
Sbjct 1857 VVSVNGTVIITNVGDTPGKPVVATENLLLDGVSYTVFQDSTTGVGHYT-VFDKEAKLMFD 1915
Query 1827 GAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPK--LDGYYKKDNAYY 1884
G L PVT V PV E++ LD ++
Sbjct 1916 GDVLKPCDLNVSPVTSVVVCNNKKIVVQDPV-------KRVELDASKFLDTMNVASEKFF 1968
Query 1885 T 1885
T
Sbjct 1969 T 1969
Score = 152 bits (383), Expect = 2e-34, Method: Composition-based stats.
Identities = 71/310 (23%), Positives = 114/310 (37%), Gaps = 22/310 (7%)
Query 1002 PVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAM 1061
V F Y N+ + + S N +VNAAN L HGGG+A AL+ T G +
Sbjct 1295 DVKPFLTYK----NIEFYQGE-LSALLSVNHDFVVNAANEQLSHGGGIAKALDDLTKGEL 1349
Query 1062 QKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDI 1121
Q S+ Y+ NG + VG L+ L+VVGP L KA F + +
Sbjct 1350 QVLSNQYVSRNGSIKVGSGVLIKCKE--HSILNVVGPRKGKHAAELLTKAYTFVFKQKGV 1407
Query 1122 LLAPLLSAGIFGAK---PLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLK----- 1173
L PLLS GIF L + CV + + + + L Q + +
Sbjct 1408 PLMPLLSVGIFKVPITESLAAFLACVGDRVCKCFCYTDKERLAIQNFVTSFQTEQPVEPL 1467
Query 1174 PRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFL--TNKLLL 1231
P ++ K + E ++ K + +L+ T+ + TN L
Sbjct 1468 PVIQEVKGVQLEKPVPDVKVENPCEPFRIEGDAKFYDLTPSMVQSLQVTRLVSFTNSDLC 1527
Query 1232 FADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSG-----DITCVVIPSKKAGGTT 1286
Q L G ++ + + G+ +T T V++P +
Sbjct 1528 LGSFVRDCDGYVQGSLGGAIANYKKSNPVLPAGNCVTLKCDGFISFTFVILPKEGDTNYE 1587
Query 1287 EMLSRALKKV 1296
+ +RA+ K
Sbjct 1588 KNFNRAIAKF 1597
Score = 64.7 bits (156), Expect = 4e-08, Method: Composition-based stats.
Identities = 38/190 (20%), Positives = 65/190 (34%), Gaps = 14/190 (7%)
Query 1626 ALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAA 1685
+ + GGL + + NNC++SS L+ LQ + ++ +Q AG +
Sbjct 1078 VKPDVFAFSYASYGGLKVLNQSSNNCWVSSALVQLQLTGL-LDSDEMQL----FNAGRVS 1132
Query 1686 NFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAV 1745
G LGDV + LL+ + S ++ C G + E
Sbjct 1133 PMVKRCYESQRAIFGSLGDVSACLESLLKDRDGMSITCTIDCGCGP-GVRVY-----ENA 1186
Query 1746 MYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMM-SAPPAEYKLQQGTFLCANEY 1804
++ T G +C + + Q + + + A + LCA Y
Sbjct 1187 IFRFTPLKTAFPMG--RCLICSKTLMHTITQMKGTGIFCRDATALDVDTLVVKPLCAAVY 1244
Query 1805 TGNYQCGHYT 1814
G GHY
Sbjct 1245 VGAQDGGHYL 1254
Score = 55.8 bits (133), Expect = 2e-05, Method: Composition-based stats.
Identities = 62/370 (17%), Positives = 123/370 (33%), Gaps = 42/370 (11%)
Query 653 ITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQ 712
+ GV V + + A ++ F+D V +++ + + +
Sbjct 750 LNGVVVFVTKKFRKAGALLQKLYNAFLDTVTSFIKVAGVAFKYCATCVPKIVIN------ 803
Query 713 SKGLYRQCIRGKEQLQLLMPLKAPKEVTFLE-GDSHDTVLTSEEVVLKNGELEALETPVD 771
+ + LQ+ P E + + V ++ LE E
Sbjct 804 -GCYHTVTRLFAKDLQI------PTEDGVADFNTFNHCVFPVNPTRIETDSLELEEV--- 853
Query 772 SFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-T 830
F + G V ++ S G + F+ KGG VT ++
Sbjct 854 DFVEPGVDGKLVILDDYSFYSDGTNYYP---SDGKGVVASCFKKKGGGV---VTISDEVQ 907
Query 831 VWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDL 890
V + VR+ +E + D+ L + C E +++TL+ D+
Sbjct 908 VRTIDPVYKVRLEYEFE---DETLVKVC-----EKAIGTKLKVTGDWSNLLETLEKAMDV 959
Query 891 LTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHE 950
+ V ++++D+ G + + + S +P + EDD + + DE +
Sbjct 960 VR------QHLDVPDYFVYDEEGGTDLNLTIMVSQWPLSSDSEDDFKAVD---DEPNANT 1010
Query 951 YGTEDDYQGLPLEFGASAETVRVEEEEEE-DWLDDTTEQSEIEPEPEPTPEEPVNQFTGY 1009
T D + E + V +E E D + TE+ IE E ++ V Q +
Sbjct 1011 DETVDTFAEDVAETQNVQQDVTQDEVEAVCDLVVKATEEGPIEHEELSEDQKEVQQALAF 1070
Query 1010 LKLTDNVAIK 1019
++ V
Sbjct 1071 IEDKPVVVKP 1080
Score = 40.4 bits (93), Expect = 1.1, Method: Composition-based stats.
Identities = 32/181 (18%), Positives = 49/181 (27%), Gaps = 42/181 (23%)
Query 180 GAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIE--SKRGVYCCRDHEHE 237
G T VD CG DG P+ +++ + +
Sbjct 109 GGTTIPVDQFMCGADGAPV---------------IQEGDWTFMDYFQDSNQFTLNGITYV 153
Query 238 IAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVI-QPRVEKKKTEG- 295
AW +R Y Q I+ + V + +K P+V K
Sbjct 154 KAWDVDRKPNDYAKQNVTCIRRITYITDH-----RHVLADGTTMKTARHPKVNKSVVLDS 208
Query 296 ------------FMGRIRSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEH 343
FMG + V ++ H L+ C C W D+ K
Sbjct 209 PFDQIYKEVGSPFMGNGSTF--VEMLKDPAFFH--ALITCE-CGRSEWTVGDW-KGYNSL 262
Query 344 C 344
C
Sbjct 263 C 263
>sp|P0C6Y4|R1AB_PEDV7 Replicase polyprotein 1ab OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=rep PE=1 SV=1
Length=6781
Score = 6818 bits (17690), Expect = 0.0, Method: Composition-based stats.
Identities = 2298/5163 (45%), Positives = 3154/5163 (61%), Gaps = 195/5163 (4%)
Query 1968 VWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMD---NLACESQQPT 2024
+W F + L + +P D+ N+ +L+
Sbjct 1753 MWESYCTGDVAMFVHWLYWLTGVDKGQPSDSENALNMLSKYIVPAGSVTIERVTHDGCCC 1812
Query 2025 SEEVVENPTIQKEVIECDVK------TTEVVGNVILKPSDEGVKVTQELG--HEDLMAAY 2076
S+ VV P + V++ V+ +G V++ +G + +G +
Sbjct 1813 SKRVVTAPVVNASVLKLGVEDGLCPHGLNYIGKVVVV---KGTTIVVNVGKPVVAPSHLF 1869
Query 2077 VENTSITIKKPNELSLALGLKTIATHGIAAINS----VPWSKILAYVKPFLGQAAITTSN 2132
++ S T N + +G T+ HG ++ VP ++ V +
Sbjct 1870 LKGVSYTTFLDNG-NGVVGHYTVFDHGTGMVHDGDAFVPGDLNVSPVTNVVVSEQTAVVI 1928
Query 2133 CAKRLAQRV----FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTI-------AKNSVK 2181
+ + M Y F F + + + + K VK
Sbjct 1929 KDPVKKAELDATKLLDTMNYASERFFSFGDFMSRNLITVFLYILSILGLCFRAFRKRDVK 1988
Query 2182 SVAKLCLDAGINYVKSPK--------FSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSN 2233
+A + GI KS + F KL +L + + +
Sbjct 1989 VLAGVPQRTGIILRKSMRYNAKALGVFFKLKLYWFKVLGKFSLGIYALYALLFMTIRFTP 2048
Query 2234 FGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL 2293
G+P C+ V Y NSS ++C S C +CL G L + + + + L
Sbjct 2049 IGSP-VCDDVVAGYANSS-FDKNEYC-NSVICKVCLYGYQELSDFSHTQVVWQHLRD-PL 2104
Query 2294 DLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVF-FGYFASH--FISNSWLMWFIISIVQ 2350
++ Y+ F F + + AI F F Y S F+ +WF+ Q
Sbjct 2105 IGNVMPFF------YLAFLAIFGGVYVKAITLYFIFQYLNSLGVFLGLQQSIWFL----Q 2154
Query 2351 MAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRS 2410
+ P + F + H+ GC ++C+ C K R RV TI G +S
Sbjct 2155 LVPFDVFGDEIVVFFIVTRVLMFIKHVCLGCDKASCVACSKSARLKRVPVQTIFQGTSKS 2214
Query 2411 FYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDS 2470
FYV+ANGG FCK HN+ CLNCD++ G TFI+D +A ++ K + PT ++ ++D
Sbjct 2215 FYVHANGGSKFCKKHNFFCLNCDSYGPGCTFINDVIATEVGNVVKLNVQPTGPATILIDK 2274
Query 2471 VAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESA 2530
V NG +LY K S + + L+ S+ + IVF+ + +
Sbjct 2275 VEFSNGFYYLYSGDTFWKYNFDITDSKYTCKEALK----NCSIITDFIVFNNNG-SNVNQ 2329
Query 2531 SKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALV 2590
K+A VY+SQ++C+P+ L+D AL++ + S + + A+V S +F + +
Sbjct 2330 VKNACVYFSQMLCKPVKLVDSALLASL--SVDFGASLHSAFVSVLSNSFGKDLSSCNDM- 2386
Query 2591 ATAHSELAKGVALDGV-LSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNN 2649
+ + D V L TF +A + +H D+ +T S NN
Sbjct 2387 ----QDCKSTLGFDDVPLDTFNAAVAE------------------AHRYDVLLTDMSFNN 2424
Query 2650 FMLTYNKVENMTP-RDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRS 2708
F +Y K E P D+ C+ A+ +N V ++ ++W V+D+++LSE+ RK I
Sbjct 2425 FTTSYAKPEEKFPVHDIATCMRVGAKIVNHNVLVKDSIPVVWLVRDFIALSEETRKYIIR 2484
Query 2709 AAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVM 2768
K I F LT R + T I+ K G + + K+ LC+ +IV
Sbjct 2485 TTKVKGITFMLTFNDCRMHTTIPTVCIANKKGAGLPSFSKVKKFFWFLCL------FIVA 2538
Query 2769 PVHTLSIHDGYT----NEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGS-YK 2823
LS D T + +K I+ G + + C N FD W + G
Sbjct 2539 AFFALSFLDFSTQVSSDSDYDFKYIESGQLKTFDNPLSCVHNVFINFDQWHDAKFGFTPV 2598
Query 2824 NDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYS 2883
N+ SCP+V + + VPG+P V + G L F +C+ S + +
Sbjct 2599 NNPSCPIVVGV--SDEARTVPGIPAGVY--LAGKTLVFAINTIFGTSGLCFDASGVAD-- 2652
Query 2884 DFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPN 2943
AC+ + CT G V YCY L+EG+ YSEL P + Y ++DG+ + P
Sbjct 2653 ---KGACIFNSACTTLSGLGGTAV-YCYKNGLVEGAKLYSELAPHSYYKMVDGNAVSLPE 2708
Query 2944 TYLEG-SVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMN 3002
G +R + T YCR G C +S G+C +V N E + S CG
Sbjct 2709 IISRGFGIRTIRTKAMTYCRVGQCVQSAEGVCFGADRFFVYNAE---SGSDFVCGTGLFT 2765
Query 3003 LIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLF 3062
L+ N+ + + V +S ++ IIA + + F KF+R+FG+ + V
Sbjct 2766 LLMNVISVFSKTVPVTVLSGQILFNCIIAFVAVAVCFLFTKFKRMFGDMSVGVFTVGACT 2825
Query 3063 LMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYV 3122
L++ + +V + Y+ Y T ++ HL + + I P+W+ +Y
Sbjct 2826 LLN-NVSYIVTQNTLGMLGYATLYFLCTK--GVRYMWIWHLGFLISYILIAPWWVLMVYA 2882
Query 3123 FCISLKHCHWFFNNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQY 3181
F + F + + +F G F +FE AA TF+L+ Y +L + + +
Sbjct 2883 FSAIFEFMPNLFKLKVSTQ-LFEGDKFVGSFENAAAGTFVLDMHAYERLANS--ISTEKL 2939
Query 3182 NRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQS 3241
+Y + YNKYKY+SG+ YR A HLAKA+ D++++ D LY PP S S LQ+
Sbjct 2940 RQYASTYNKYKYYSGSASEADYRLACFAHLAKAMMDYASNHNDTLYTPPTVSYNST-LQA 2998
Query 3242 GFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRK 3301
G RKMA PSG VE C+V+V G LNGLWL D V CPRHVI ++ +Y+ L
Sbjct 2999 GLRKMAQPSGVVEKCIVRVCYGNMALNGLWLGDIVMCPRHVIASSTT-STIDYDYALSVL 3057
Query 3302 SNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGS 3361
H+F + +GNV L V+ +M+ LL++KV+ +N TPKY + ++PG++F++LACY+G+
Sbjct 3058 RLHNFSISSGNVFLGVVSATMRGALLQIKVNQNNVHTPKYTYRTVRPGESFNILACYDGA 3117
Query 3362 PSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKF 3421
+GVY MR N+TI+GSF+NG+CGS G+NI+ V FCY+H +EL +G H G+DL+G
Sbjct 3118 AAGVYGVNMRSNYTIRGSFINGACGSPGYNINNGTVEFCYLHQLELGSGCHVGSDLDGVM 3177
Query 3422 YGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEP 3481
YG + D+ T Q G + T NVLA+LYAA+ING W+L+ ++ FN A+
Sbjct 3178 YGGYEDQPTLQVEGASSLFTENVLAFLYAALINGSTWWLSSSRIAVDRFNEWAVHNGMTT 3237
Query 3482 LTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCS 3541
+ + D L+A+TG+ V + A+++ L +N G+ ILG T L DEFT +VVRQ
Sbjct 3238 VG--NTDCFSILAAKTGVDVQRLLASIQSLHKN-FGGKQILGHTSLTDEFTTGEVVRQMY 3294
Query 3542 GVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAAC 3601
GV QG + + + + +L+ + + ++ FF+V P + +++
Sbjct 3295 GVNLQGGY--VSRACRNVLLVGSFLT-FFWSELVSYTKFFWVNPGYVTPMFACLSLLSSL 3351
Query 3602 AMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVM 3661
M +KHK F +FL+P+L + N+ + + + SL G+ + V
Sbjct 3352 LMFTLKHKTLFFQVFLIPALIVTSCINLAFDVEVY--NYLAEHFDYHVSLMGFNAQGLVN 3409
Query 3662 YASALVLLILM---TARTVYDDAARRVWTLMNVITLVYKVYYGNA-LDQAISMWALVISV 3717
V+ IL T R A V ++ ++T Y +Y + L A++++A SV
Sbjct 3410 IFVCFVVTILHGTYTWRFFNT-PASSVTYVVALLTAAYNYFYASDILSCAMTLFA---SV 3465
Query 3718 TSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLL 3777
T N V + + + V++ + + P ++ +M Y LGY CC++G+
Sbjct 3466 TGN--WFVGAVCY--KVAVYMALRF-PTFVAIFGDIKSVMFCYLVLGYFTCCFYGILYWF 3520
Query 3778 NRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQS 3837
NR+F++++GVYDY VS EF+YM + GL P ++D+ L+ KL+GIGG+ IK+++VQS
Sbjct 3521 NRFFKVSVGVYDYTVSAAEFKYMVANGLRAPTGTLDSLLLSAKLIGIGGERNIKISSVQS 3580
Query 3838 KMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLS 3897
K++D+KC++VVLL L + V ++S WA CV LHN I L D +A E +++LL+ LS
Sbjct 3581 KLTDIKCSNVVLLGCLSSMNVSANSTEWAYCVDLHNKINLCNDPEKAQEMLLALLAFFLS 3640
Query 3898 MQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKL 3957
A ++ L E ++ + LQ++AS + LPSY Y A++ YE AV NG ++K+L
Sbjct 3641 KNSAFGLDDLLESYFNDNSMLQSVASTYVGLPSYVIYENARQQYEDAVNNGSPPQLVKQL 3700
Query 3958 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4017
+ ++NVAKSEFDR+A+ QRKL++MA+QA QMYK+AR+ ++++KV SAM ++LF MLR+L
Sbjct 3701 RHAMNVAKSEFDREASTQRKLDRMAEQAAAQMYKEARAVNRKSKVVSAMHSLLFGMLRRL 3760
Query 4018 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQ 4077
D +++ I+N A+DG VPL++IP +A KL +V D +Y YA +W I
Sbjct 3761 DMSSVDTILNLAKDGVVPLSVIPAVSATKLNIVTSDIDSYNRIQREGCVHYAGTIWNIID 3820
Query 4078 VVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQ 4137
+ D D K+V + E+ N+ +L+WPL++ R VKLQNNE+ P L+Q S A
Sbjct 3821 IKDNDGKVVHVKEVTAQNAESLSWPLVLGCER---IVKLQNNEIIPGKLKQRSIKAEGDG 3877
Query 4138 TACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTP 4197
A YNN G F+ A +SD DL+ ++ G TI ELEPP +F+ D+P
Sbjct 3878 IV---GEGKALYNNEGGRTFMYAFISDKPDLRVVKWEFDGGCNTI--ELEPPRKFLVDSP 3932
Query 4198 KGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAY 4257
G ++KYLYF++ LN L RG VLG + ATVRLQAG TE NS++L+ CAFAVDPAK Y
Sbjct 3933 NGAQIKYLYFVRNLNTLRRGAVLGYIGATVRLQAGKQTEQAINSSLLTLCAFAVDPAKTY 3992
Query 4258 KDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPK 4317
D + SG +P+ NCVKML +G GQA+T EA+ +Q+S+GGAS CLYCR H++HP+
Sbjct 3993 IDAVKSGHKPVGNCVKMLANGSGNGQAVTNGVEASTNQDSYGGASVCLYCRAHVEHPSMD 4052
Query 4318 GFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFL 4377
GFC LKGKYVQ+P DP+ F L N VC VCG W GC+CD+ +MQS D + +L
Sbjct 4053 GFCRLKGKYVQVPLGTV-DPIRFVLENDVCKVCGCWLSNGCTCDR---SIMQSTDMA-YL 4107
Query 4378 NRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDS 4437
NRV G SAARL PC GT T VYRAFDIYN+ VA KFLK NC R + D+ D+
Sbjct 4108 NRVRGSSAARLEPC-NGTDTQHVYRAFDIYNKDVACLGKFLKVNCVRLKNLDKH----DA 4162
Query 4438 YFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLV 4497
++VVKR T S +HE++IY+ ++ C A+A HDFF ++ + ++ R+ LT+YTM DL
Sbjct 4163 FYVVKRCTKSAMEHEQSIYSRLEKCGAIAEHDFFTWKDGRAIYGNVCRKDLTEYTMMDLC 4222
Query 4498 YALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLK 4557
YALR+FDE NCD LK IL+ C++ YFN K W+D VEN DI RVYA LG V +++LK
Sbjct 4223 YALRNFDENNCDVLKSILIKVGACEESYFNNKVWFDPVENEDIHRVYALLGTIVARAMLK 4282
Query 4558 TVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLT 4617
V+FCDAM + GIVGV+TLDNQDLNG++YDFGDF G GVPI SYYS +MP++ +T
Sbjct 4283 CVKFCDAMVEQGIVGVVTLDNQDLNGDFYDFGDFTCSIKGMGVPICTSYYSYMMPVMGMT 4342
Query 4618 RALAAESHMDADL-AKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCI 4676
LA+E + +D+ + +DLL+YDFTE + LF++YFKYW YHPNC++C D++CI
Sbjct 4343 NCLASECFVKSDIFGEDFKSYDLLEYDFTEHKTALFNKYFKYWGLQYHPNCVDCSDEQCI 4402
Query 4677 LHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLS 4736
+HCANFN LFST P T+FGPL RK ++DGVP V + GYHF++LG+V N D+NLHSSRLS
Sbjct 4403 VHCANFNTLFSTTIPITAFGPLCRKCWIDGVPLVTTAGYHFKQLGIVWNNDLNLHSSRLS 4462
Query 4737 FKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKG 4796
ELL + +DPA+ AS L+D+RT CFSVAAL + QTVKPG+FNK+FYDF + +G
Sbjct 4463 INELLQFCSDPALLIASSPALVDQRTVCFSVAALGTGMTNQTVKPGHFNKEFYDFLLEQG 4522
Query 4797 FFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGC 4856
FF EGS + LKHFFFAQ +AA+ D+DYYRYN PT+ DI Q V ++V +YFD Y+GGC
Sbjct 4523 FFSEGSELTLKHFFFAQKVDAAVKDFDYYRYNRPTVLDICQARVVYQIVQRYFDIYEGGC 4582
Query 4857 INANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYA 4916
I A +V+V NL+KSAG+P NK+GKA LYY+S+SYE+QD L+AYTKRN++PT+TQ+NLKYA
Sbjct 4583 ITAKEVVVTNLNKSAGYPLNKFGKAGLYYESLSYEEQDELYAYTKRNILPTMTQLNLKYA 4642
Query 4917 ISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYS 4976
IS K RARTV GVS+ STMT RQ+HQK LKSI TRGA+VVIGT+KFYGGW NMLK +
Sbjct 4643 ISGKERARTVGGVSLLSTMTTRQYHQKHLKSIVNTRGASVVIGTTKFYGGWDNMLKNLID 4702
Query 4977 DVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMV 5036
VE P LMGWDYPKCDRA+PNM+R++++++L KH TCC+ + RF+RL NE AQVL+E+V
Sbjct 4703 GVENPCLMGWDYPKCDRALPNMIRMISAMILGSKHTTCCSSTDRFFRLCNELAQVLTEVV 4762
Query 5037 MCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRL 5096
G Y+KPGGT+SGDATTAYANSVFNI QAV+ANVN LLS D N + V+ LQ +L
Sbjct 4763 YSNGGFYLKPGGTTSGDATTAYANSVFNIFQAVSANVNKLLSVDSNVCHNLEVKQLQRKL 4822
Query 5097 YECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLY 5156
YEC YR+ VD +FV E+Y YLRKHFSMMILSDD VVCYN++YA+ G VA + FKAVLY
Sbjct 4823 YECCYRSTIVDDQFVVEYYGYLRKHFSMMILSDDGVVCYNNDYASLGYVADLNAFKAVLY 4882
Query 5157 YQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDI 5216
YQNNVFMS +KCW E D+ KGPHEFCSQHTM + + YLPYPDPSRIL AG FVDD+
Sbjct 4883 YQNNVFMSASKCWIEPDINKGPHEFCSQHTMQIVDKEGTYYLPYPDPSRILSAGVFVDDV 4942
Query 5217 VKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVML 5276
VKTD +++ER+VSLAIDAYPL+KH N EY VF++ L +++ L+ L +L+ +SV L
Sbjct 4943 VKTDAVVLLERYVSLAIDAYPLSKHENPEYKKVFYVLLDWVKHLYKTLNAGVLESFSVTL 5002
Query 5277 TNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVI 5336
D+T+++W+ FY MY VLQ+ G CV+C SQT LRCG C+RRP LC KC YDHVI
Sbjct 5003 LEDSTAKFWDESFYANMYEKSAVLQSAGLCVVCGSQTVLRCGDCLRRPMLCTKCAYDHVI 5062
Query 5337 STSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKN 5396
T+HK +L++ PYVC A C V DVT+LYLGG+SY+C HKP ++FPLC+ G VFGLYKN
Sbjct 5063 GTTHKFILAITPYVCCASDCGVNDVTKLYLGGLSYWCHEHKPRLAFPLCSAGNVFGLYKN 5122
Query 5397 TCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVR 5456
+ GS +V DFN IAT DWT+ DY LAN + L+LFAAET+KA EE+ K SY AT+
Sbjct 5123 SATGSPDVEDFNRIATSDWTDVSDYRLANDVKDSLRLFAAETIKAKEESVKSSYACATLH 5182
Query 5457 EVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDY-GDAVVYRGT 5515
EV+ +EL L WEVG+P+PPLNRN VFT Y +TKN+K QIGE+ FEK +Y DAV Y+ T
Sbjct 5183 EVVGPKELLLKWEVGRPKPPLNRNSVFTCYHITKNTKFQIGEFVFEKAEYDNDAVTYKTT 5242
Query 5516 TTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGM 5575
T KL G FVLTSH V PL APT+ QE Y I L+P NI + +SS V YQ +G
Sbjct 5243 ATTKLVPGMVFVLTSHNVQPLRAPTIANQERYSTIHKLHPAFNIPEAYSSLVPYYQLIGK 5302
Query 5576 QKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5635
QK +T+QGPPG+GKSH IGL LYYP ARIV+TACSHAAVD+LC KA DKCSRII
Sbjct 5303 QKITTIQGPPGSGKSHCVIGLGLYYPGARIVFTACSHAAVDSLCVKASTAYSNDKCSRII 5362
Query 5636 PARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK 5695
P RARVEC+D FK N+T QY+F TVNALPE ADIVV DE+SM TNYDLSV+N R+ +
Sbjct 5363 PQRARVECYDGFKSNNTSAQYLFSTVNALPECNADIVVVDEVSMCTNYDLSVINQRISYR 5422
Query 5696 HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSA 5755
H VY+GDP QLPAPR ++++GTLEP+ +N V + M + PD+FL C RCPAEIV TVS
Sbjct 5423 HVVYVGDPQQLPAPRVMISRGTLEPKDYNVVTQRMCALKPDVFLHKCYRCPAEIVRTVSE 5482
Query 5756 LVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISP 5815
+VY+N+ S QCFK+F KG + D S+INR Q+ VVR FL +NP W KAVFISP
Sbjct 5483 MVYENQFIPVHPDSKQCFKIFCKGNVQVDNGSSINRRQLDVVRMFLAKNPRWSKAVFISP 5542
Query 5816 YNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILC 5875
YNSQN VAS++LGL QTVDSSQGSEYDYVI+ QT++TAH+ NVNRFNVAITRAK GILC
Sbjct 5543 YNSQNYVASRLLGLQIQTVDSSQGSEYDYVIYAQTSDTAHASNVNRFNVAITRAKKGILC 5602
Query 5876 IMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKF 5935
IM DR L+D L+F L++ + LQA GLFKDCS+ L P+ A T +S+ F
Sbjct 5603 IMCDRSLFDLLKFFELKL-----SDLQANEGCGLFKDCSRGDDLLPPSHANTFMSLADNF 5657
Query 5936 KTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEG 5995
KT+ G+ + Y +IS MGF+ + + + +F TR+ A+R+VR W+GFDVEG
Sbjct 5658 KTDQYLAVQIGVNGPIKYEHVISFMGFRFDINIPNHHTLFCTRDFAMRNVRGWLGFDVEG 5717
Query 5996 CHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLM 6055
H VGTN+PLQLGFS GV+ V P G V TE+ V A+ PPG+QF HL+PL+
Sbjct 5718 AHVVGSNVGTNVPLQLGFSNGVDFVVRPEGCVVTESGDYIKPVRARAPPGEQFAHLLPLL 5777
Query 6056 YKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKR 6115
+G PW+VVR +IVQM SD L LSD ++FVLWA G ELT+M+YFVKIGP ++C C K
Sbjct 5778 KRGQPWDVVRKRIVQMCSDYLANLSDILIFVLWAGGLELTTMRYFVKIGPSKSC-DCGKV 5836
Query 6116 ATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCD 6175
ATC++++ TY C+ H++G DY+YNP+ ID+QQWG+ G+L NH +HC VH N HVAS D
Sbjct 5837 ATCYNSALHTYCCFKHALGCDYLYNPYCIDIQQWGYKGSLSLNHHEHCNVHRNEHVASGD 5896
Query 6176 AIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIG 6235
AIMTRCLA+H+CFVK VDWS+ YP IG+E +N + R VQ ++S L ++DIG
Sbjct 5897 AIMTRCLAIHDCFVKNVDWSITYPFIGNEAVINKSGRIVQSHTMRSVLKLYNPKAIYDIG 5956
Query 6236 NPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYP 6295
NPK I+C + +W +D P + +E Y Y TH DG+CLFWNCNVD YP
Sbjct 5957 NPKGIRCA-VTDAKWFCFDKNPTNSNVKTLE---YDYITHGQ--FDGLCLFWNCNVDMYP 6010
Query 6296 ANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCE 6355
++VCRFDTR S LNL GC+GGSLYVN HAFHTPAFDK AF LK +PFF+Y D+ C+
Sbjct 6011 EFSVVCRFDTRCRSPLNLEGCNGGSLYVNNHAFHTPAFDKRAFAKLKPMPFFFYDDTECD 6070
Query 6356 SHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQ 6415
++ I+YVPL+++ CIT+CN+GGAVC H Y Y++AYN SAGF++W+
Sbjct 6071 ----KLQDSINYVPLRASNCITKCNVGGAVCSKHCAMYHSYVNAYNTFTSAGFTIWVPTS 6126
Query 6416 FDTYNLWNTFT-RLQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFEN 6474
FDTYNLW TF+ LQ LEN+A+NV+ KG F G GE PV+++N+ V + +D +F N
Sbjct 6127 FDTYNLWQTFSNNLQGLENIAFNVLKKGSFVGDEGELPVAVVNDKVLVRDGTVDTLVFTN 6186
Query 6475 KTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMT 6534
KT+LP NVAFEL+AKR + P I IL NLGV + VIWDY+ E P T VC T
Sbjct 6187 KTSLPTNVAFELYAKRKVGLTPPITILRNLGVVCTSKCVIWDYEAERPLTTFTKDVCKYT 6246
Query 6535 DIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGV 6594
D + LFD + G ++ F +N VL++ +VK LT K +NGV
Sbjct 6247 DFE--------GDVCTLFDNSIVGSLERFSMTQNAVLMSLTAVKKLTGIK-LTYGYLNGV 6297
Query 6595 TLIGESVK--TQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQ 6652
+ K T + Y +K +G + P+ YFTQ R DF PRS ME DFL + M FI
Sbjct 6298 PVNTHEDKPFTWYIYTRK-NGKFEDYPDGYFTQGRTTADFSPRSDMEKDFLSMDMGLFIN 6356
Query 6653 RYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPM-DSTVKNYFITD 6711
+Y LE Y FEH+VYGD S LGGLHL+I + + LK+++F+ DST+K+ +T
Sbjct 6357 KYGLEDYGFEHVVYGDVSKTTLGGLHLLISQVRLACMGVLKIDEFVSSNDSTLKSCTVTY 6416
Query 6712 AQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFY 6771
A SSK VC+ +DLLLDDFV I+KS DLSV+SKV +V +D +MLWCKD ++TFY
Sbjct 6417 ADNPSSKMVCTYMDLLLDDFVSILKSLDLSVVSKVHEVMVDCKMWRWMLWCKDHKLQTFY 6476
Query 6772 PKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNT 6831
P+LQAS+ W+ G +MP++YK+QRM LE C+L NYG +P GIM NV KYTQLCQYLN+
Sbjct 6477 PQLQASE-WKCGYSMPSIYKIQRMCLEPCNLYNYGAGVKLPDGIMFNVVKYTQLCQYLNS 6535
Query 6832 LTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCA 6891
T+ VP++MRV+H GAGSDKGVAPGTAVLR+WLP ++VD+D D+VSDAD ++ GDC+
Sbjct 6536 TTMCVPHHMRVLHLGAGSDKGVAPGTAVLRRWLPLDAIIVDNDSVDYVSDADYSVTGDCS 6595
Query 6892 TVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSW 6951
T++ ++K+DL+ISDMYD + K EN SKEGFF Y+ G I +KLALGG++A+K+TE SW
Sbjct 6596 TLYLSDKFDLVISDMYDGKIKSCDGENVSKEGFFPYINGVITEKLALGGTVAIKVTEFSW 6655
Query 6952 NADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGKP--KEQIDGYTMHANYIFWRNT 7009
N LY+L+ F +WT F T+VN SSSEAFLIG +YLG IDG TMHANYIFWRN+
Sbjct 6656 NKKLYELIQKFEYWTMFCTSVNTSSSEAFLIGVHYLGDFASGAVIDGNTMHANYIFWRNS 6715
Query 7010 NPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDI 7069
+ +S S+ D+SKF K + T V++LK++ I+D++ LL+ G+L++R N+ + S+
Sbjct 6716 TIMTMSYNSVLDLSKFNCKHKATVVVNLKDSSISDVVLGLLKNGKLLVRNNDAICGFSNH 6775
Query 7070 LVN 7072
LVN
Sbjct 6776 LVN 6778
Score = 244 bits (624), Expect = 2e-62, Method: Composition-based stats.
Identities = 77/325 (24%), Positives = 120/325 (37%), Gaps = 33/325 (10%)
Query 1543 KTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
K++ + T D ++ V+ + TYGQQ GP ++ VT KP V V+P+ +
Sbjct 1631 KSVVIKVTEDTRSVKAVKVESTATYGQQIGPCLVNDTVVTDNKPVVADV--VAKVVPNAN 1688
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTK-KWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
F+ L+HT + V G IK DNNC+++ L LQ
Sbjct 1689 WDSHYGFDKAGEF---------HMLDHTGFTFPSEVVNGRRVIKTTDNNCWVNVTCLQLQ 1739
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQH---ANL 1718
+F + LQ + GD A F + + G+ D + L ++ A
Sbjct 1740 FARFRFKSAGLQAMWESYCTGDVAMFVHWLYWLTGVDKGQPSDSENALNMLSKYIVPAGS 1799
Query 1719 ESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIP-CVCGRDATQYLVQQ 1777
+ +RV + C C ++ T V A + LK GV C G + +V
Sbjct 1800 VTIERVTHDGC-CCSKRVVTAPVVNASV---------LKLGVEDGLCPHGLNYIGKVVVV 1849
Query 1778 ESSFVMMSAPPAEYKLQQGTFLCANEYT-----GNYQCGHYTHITAKETLYRIDGAHLTK 1832
+ + +++ FL YT GN GHYT + DG
Sbjct 1850 KGTTIVV-NVGKPVVAPSHLFLKGVSYTTFLDNGNGVVGHYTVFDHGTGMVH-DGDAFVP 1907
Query 1833 MSEYKGPVTDVFYKETSYTTTIKPV 1857
PVT+V E + PV
Sbjct 1908 GDLNVSPVTNVVVSEQTAVVIKDPV 1932
Score = 216 bits (551), Expect = 5e-54, Method: Composition-based stats.
Identities = 92/326 (28%), Positives = 142/326 (44%), Gaps = 28/326 (9%)
Query 988 QSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGG 1047
+ + P + E V F Y NV D + +VNAAN L HGG
Sbjct 1275 TAPLVPAVDSVVEPVVKPFYSYK----NVDFYQGDFSDLVK-LPCDFVVNAANEKLSHGG 1329
Query 1048 GVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQ 1107
G+A A++ T G +QK S+DYIK +GP+ VG +L L K +VVGP
Sbjct 1330 GIAKAIDVYTKGMLQKCSNDYIKAHGPIKVGRGVMLEA--LGLKVFNVVGPRKGKHAPEL 1387
Query 1108 LLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMD 1167
L+KA F + + L PL+S GIF +SL + V + + ++
Sbjct 1388 LVKAYKSVFANSGVALTPLISVGIFSVPLEESLSAFLACVGDRHCKCFCYGDKEREAIIK 1447
Query 1168 YLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPV--DVKP-KIKA------CIDEVTTT 1218
Y+D L V+A +E +T + + + V QKPV + +P +I+ C E +
Sbjct 1448 YMDGL---VDAIFKEALVDTTPVQEDVQQVSQKPVLPNFEPFRIEGAHAFYECNPEGLMS 1504
Query 1219 LEETKFL--TNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYM-VGDVITSG----- 1270
L K + TN L F + GK +D + E ++ +K + G+ +T
Sbjct 1505 LGADKLVLFTNSNLDFCSV-GKCLNDVTSGALLEAINVFKKSNKTVPAGNCVTLDCANMI 1563
Query 1271 DITCVVIPSKKAGGTTEMLSRALKKV 1296
IT VV+P + +RA+ KV
Sbjct 1564 SITMVVLPFDGDANYDKNYARAVVKV 1589
Score = 63.5 bits (153), Expect = 1e-07, Method: Composition-based stats.
Identities = 49/260 (19%), Positives = 83/260 (32%), Gaps = 29/260 (11%)
Query 1632 KWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALI 1691
+ F GGL ++ + NNC+++S L+ LQ L + + A AG
Sbjct 1072 AFDFVSYGGLKVLRQSHNNCWVTSTLVQLQLLGIVDDP-----AMELFSAGRVGPMVRKC 1126
Query 1692 LAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTL 1751
+G LGDV + L + +L + K +VVC CG G + T
Sbjct 1127 YESQKAILGSLGDVSACLESLTK--DLHTLKITCSVVCG-CGTGERIYEG---CAFRMTP 1180
Query 1752 SYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPA-EYKLQQGTFLCANEYTGNYQC 1810
+ + C + + + A LCA + G
Sbjct 1181 TLEPF--PYGACAQCAQVLMHTFKSIVGTGIFCRDTTALSLDSLVVKPLCAAAFIGK-DS 1237
Query 1811 GHYT--HITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTE 1868
GHY A + + + V DV + P+ +D V
Sbjct 1238 GHYVTNFYDAAMAIDGYGRHQIKYDTLNTICVKDVNWTA--------PLVPAVDSVVEPV 1289
Query 1869 IEPKLDGYYKKDNAYYTEQP 1888
++P +Y N + +
Sbjct 1290 VKP----FYSYKNVDFYQGD 1305
Score = 62.4 bits (150), Expect = 2e-07, Method: Composition-based stats.
Identities = 49/212 (23%), Positives = 72/212 (34%), Gaps = 43/212 (20%)
Query 172 ELTRELNGGAVTRYVDNNFCGPDGYPLD-----CIKDFLARAGKSMCTLSEQLDYIESKR 226
ELT GG + VD CG DG P+ DF A +S+
Sbjct 102 ELTFGRRGGNIVP-VDQYMCGADGKPVLQESEWEYTDFFA----------------DSED 144
Query 227 GVYCCRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVI-Q 285
G + AW ERSD SY Q IKS T++ F + +KV
Sbjct 145 GQLNIAGITYVKAWIVERSDVSYASQNLTSIKSITYCSTYE-----HTFLDGTAMKVART 199
Query 286 PRVEKKKTEGFMGRIRSVYPVASPQECNN-----------MHLSTLMKCNHCDEVSWQTC 334
P+++K + ++Y +N + L +KC C W
Sbjct 200 PKIKKNVV--LSEPLATIYREIGSPFVDNGSDARSIIRRPVFLHAFVKCK-CGSYHWTVG 256
Query 335 DFLKATCEHCGTENLVIEGPTTCGYLPTNAVV 366
D+ CG + +C +P + VV
Sbjct 257 DWTSYVSTCCGFK-CKPVLVASCSAMPGSVVV 287
>sp|P0C6X5|R1AB_CVHNL Replicase polyprotein 1ab OS=Human coronavirus
NL63 OX=277944 GN=rep PE=1 SV=1
Length=6729
Score = 6803 bits (17650), Expect = 0.0, Method: Composition-based stats.
Identities = 2270/5007 (45%), Positives = 3106/5007 (62%), Gaps = 165/5007 (3%)
Query 2096 LKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQ 2155
L T+A I + S + P + I+ + AQ+ F + +V +
Sbjct 1858 LSTLAVTAIVVVGGCVTSNV-----PTIVSEKISVMDKLDTGAQKFFQ-FGDFVMNNIVL 1911
Query 2156 LCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKF---SKLFTIAM-WLL 2211
T+ S S +R T+I K+ +K +AK G+ +S K+ S LF I W +
Sbjct 1912 FLTWLLSMFSLLR----TSIMKHDIKVIAKAPKRTGVILTRSFKYNIRSALFVIKQKWCV 1967
Query 2212 LLSICLGSLICVTAAFGVLLSNFGAPS---YCNGVRELYLNSSNVTTMDFCEGSFPCSIC 2268
++++ L+ V + +P C + Y S+ +C S C +C
Sbjct 1968 IVTLFKFLLLLYAIYALVFMIVQFSPFNSLLCGDIVSGYEKST-FNKDIYCGNSMVCKMC 2026
Query 2269 LSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYML-FTKFFYLLGLSAIMQVF 2327
L + + I D ++ L +L +L F + GL + F
Sbjct 2027 LFSYQEFNDLDHTSLVWKHIR----DPILISLQPFVILVILLIFGNMYLRFGLLYFVAQF 2082
Query 2328 FGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCM 2387
F S F+ WF+ P + ++ I HI+ GC ++ C+
Sbjct 2083 ISTFGS-FLGFHQKQWFL----HFVPFDVLCNEFLATFIVCKIVLFVRHIIVGCNNADCV 2137
Query 2388 MCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVA 2447
C K R RV TI+NGM +SFYV ANGG FC HN+ C+NCD+F G+TFI+ ++A
Sbjct 2138 ACSKSARLKRVPLQTIINGMHKSFYVNANGGTCFCNKHNFFCVNCDSFGPGNTFINGDIA 2197
Query 2448 RDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRAN 2507
R+L K + PT + I+D V NG LY + S + + L+
Sbjct 2198 RELGNVVKTAVQPTAPAYVIIDKVDFVNGFYRLYSGDTFWRYDFDITESKYSCKEVLKNC 2257
Query 2508 NTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKM 2567
N N IV++ S + + K+A VY+SQL+C+PI L++ L+S + S + + +
Sbjct 2258 NV----LENFIVYNN-SGSNITQIKNACVYFSQLLCEPIKLVNSELLSTL--SVDFNGVL 2310
Query 2568 FDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKD 2627
AYVD +F ++L A ++ A + G+ V D
Sbjct 2311 HKAYVDVLCNSF---FKELTANMSMAECKATLGLT--------------------VSDDD 2347
Query 2628 VIECLKLSHHSDLEVTGDSCNNFMLTYNKV-ENMTPRDLGACIDCNARHINAQVAKSHNV 2686
+ + +H D+ ++ S NNF ++Y K + ++ D+ C+ ++ +N V ++
Sbjct 2348 FVSAVANAHRYDVLLSDLSFNNFFISYAKPEDKLSVYDIACCMRAGSKVVNHNVLIKESI 2407
Query 2687 SLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTC 2746
++W VKD+ +LS++ +K + K + F LT + + V T I K G
Sbjct 2408 PIVWGVKDFNTLSQEGKKYLVKTTKAKGLTFLLTFNDNQAITQVPATSIVAKQGAGFKRT 2467
Query 2747 FKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFAN 2806
+ + L V + + T++ GY +K I++G + + C N
Sbjct 2468 YNFLWYVCLFVVALFIGVSFIDYTTTVTSFHGY-----DFKYIENGQLKVFEAPLHCVRN 2522
Query 2807 KHAGFDAWFSQRGGSYK-NDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRV 2865
F+ W + G N CP+V + R +VPG+P V + G L F +
Sbjct 2523 VFDNFNQWHEAKFGVVTTNSDKCPIVVGVSERI--NVVPGVPTNVY--LVGKTLVFTLQA 2578
Query 2866 FSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSEL 2925
+CY + C+ + CT + G V YCY+T+L+EGS YS L
Sbjct 2579 AFGNTGVCYDFDGVTTSD-----KCIFNSACTRLEGLGGDNV-YCYNTDLIEGSKPYSTL 2632
Query 2926 RPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLN 2984
+P+ Y + ++FP G +R + T YCR G C S G+C +W +N
Sbjct 2633 QPNAYYKYDAKNYVRFPEILARGFGLRTIRTLATRYCRVGECRDSHKGVCFGFD-KWYVN 2691
Query 2985 NEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKF 3044
+ R G CG ++L+ N+ + + +S ++ + A +T + KF
Sbjct 2692 DG--RVDDGYICGDGLIDLLVNVLSIFSSSFSVVAMSGHMLFNFLFAAFITFLCFLVTKF 2749
Query 3045 RRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDV--SFLAH 3102
+RVFG+ ++ V L++ I +V F +Y++ Y F FT V +++ H
Sbjct 2750 KRVFGDLSYGVFTVVCATLIN-NISYVVTQNLFFMLLYAILY----FVFTRTVRYAWIWH 2804
Query 3103 LQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTF-STFEEAALCTFL 3161
+ + + ++P+W+ + F L+ F + + +F G F TFE AA TF+
Sbjct 2805 IAYIVAYFLLIPWWLLTWFSFAAFLELLPNVFKLKISTQ-LFEGDKFIGTFESAAAGTFV 2863
Query 3162 LNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNS 3221
L+ Y +L + + + Y A YNKYKY+SG+ YR A HLAKA+ D++
Sbjct 2864 LDMRSYERLINT--ISPEKLKNYAASYNKYKYYSGSASEADYRCACYAHLAKAMLDYAKD 2921
Query 3222 GADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRH 3281
D+LY PP S S LQSG +KMA PSG VE C+V+V G+T LNG+WL DTV CPRH
Sbjct 2922 HNDMLYSPPTISYNST-LQSGLKKMAQPSGCVERCVVRVCYGSTVLNGVWLGDTVTCPRH 2980
Query 3282 VICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKY 3341
VI + +L +Y+ H+F V V L V+G +M +LR+KV SN TPK+
Sbjct 2981 VIAPSTTVL-IDYDHAYSTMRLHNFSVSHNGVFLGVVGVTMHGSVLRIKVSQSNVHTPKH 3039
Query 3342 KFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYD-CVSFC 3400
F ++PG +F++LACY G SGV+ +R N TIKGSF+NG+CGS G+N+ D V FC
Sbjct 3040 VFKTLKPGDSFNILACYEGIASGVFGVNLRTNFTIKGSFINGACGSPGYNVRNDGTVEFC 3099
Query 3401 YMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFL 3460
Y+H +EL +G H G+D G YG F D+ + Q + ++ NV+A+LYAA++NG RW+L
Sbjct 3100 YLHQIELGSGAHVGSDFTGSVYGNFDDQPSLQVESANLMLSDNVVAFLYAALLNGCRWWL 3159
Query 3461 NRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRT 3520
++ FN AM Y ++ V+ L+A+TG++V + A+++ L G G+
Sbjct 3160 CSTRVNVDGFNEWAMANGYTSVSS--VECYSILAAKTGVSVEQLLASIQHL-HEGFGGKN 3216
Query 3521 ILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLF 3580
ILG + L DEFT +VV+Q GV Q K++ G L + ++ ++
Sbjct 3217 ILGYSSLCDEFTLAEVVKQMYGVNLQSG--KVIFGLKTMFLFSVFFTMFWAELFI-YTNT 3273
Query 3581 FFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRI 3640
++ P ++ ++ + +KHK FL +FLLP++ A +N V ++++
Sbjct 3274 IWINPVILTPIFCLLLFLSLVLTMFLKHKFLFLQVFLLPTVIATALYNCVLD--YYIVKF 3331
Query 3641 MTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYY 3700
+ + S+ ++ V L ++ L T R + + ++I + Y +Y
Sbjct 3332 LADHFNYNVSVLQMDVQGLVNVLVCLFVVFLHTWRFSKERFTHWFTYVCSLIAVAYTYFY 3391
Query 3701 GNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVY 3760
+S+ + + S+ + + L+R IVF E +F ++ ++VY
Sbjct 3392 SGDF---LSLLVMFLCAISSDWYIGAIVFRLSRLIVFFSPE---SVFSVFGDVKLTLVVY 3445
Query 3761 CFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIK 3820
GY C Y+G+ NR+F+ T+GVYD+ VS EF+YM + GL P DA L+ K
Sbjct 3446 LICGYLVCTYWGILYWFNRFFKCTMGVYDFKVSAAEFKYMVANGLHAPHGPFDALWLSFK 3505
Query 3821 LLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKD 3880
LLGIGG CIK++TVQSK++D+KCT+VVLL L + + ++S WA CV LHN I L D
Sbjct 3506 LLGIGGDRCIKISTVQSKLTDLKCTNVVLLGCLSSMNIAANSSEWAYCVDLHNKINLCDD 3565
Query 3881 TTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEA 3940
+A +++LL+ LS ++ L + DN +TLQ++AS F S+PSY AY A++A
Sbjct 3566 PEKAQSMLLALLAFFLSKHSDFGLDGLIDSYFDNSSTLQSVASSFVSMPSYIAYENARQA 3625
Query 3941 YEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRA 4000
YE A+ANG S ++K+LK+++N+AKSEFD + ++Q+K+ +MA+QA TQMYK+ARS ++++
Sbjct 3626 YEDAIANGSSSQLIKQLKRAMNIAKSEFDHEISVQKKINRMAEQAATQMYKEARSVNRKS 3685
Query 4001 KVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNT 4060
KV SAM ++LF MLR+LD ++ ++N ARDG VPL++IP T+A+KL +V PD +Y
Sbjct 3686 KVISAMHSLLFGMLRRLDMSSVETVLNLARDGVVPLSVIPATSASKLTIVSPDLESYSKI 3745
Query 4061 CDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNE 4120
+ YA +W + V D D + V + EI +N L WPLI+ R VKLQNNE
Sbjct 3746 VCDGSVHYAGVVWTLNDVKDNDGRPVHVKEITKENVETLTWPLILNCER---VVKLQNNE 3802
Query 4121 LSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTG 4180
+ P L+Q A D NAL YN G F+ A +S+ DLK+ ++ G
Sbjct 3803 IMPGKLKQKPMKAEGDGGVLGDGNAL--YNTEGGKTFMYAYISNKADLKFVKWEYEGGCN 3860
Query 4181 TIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPAN 4240
TI EL+ PCRF+ +TP GP+VKYLYF+K LN L RG VLG + AT+RLQAG TE+ N
Sbjct 3861 TI--ELDSPCRFMVETPNGPQVKYLYFVKNLNTLRRGAVLGFIGATIRLQAGKQTELAVN 3918
Query 4241 STVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGG 4300
S +L+ CAF+VDPA Y + + G +P++NC+KML G GQAIT + +AN +Q+S+GG
Sbjct 3919 SGLLTACAFSVDPATTYLEAVKHGAKPVSNCIKMLSNGAGNGQAITTSVDANTNQDSYGG 3978
Query 4301 ASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSC 4360
AS CLYCR H+ HP+ G+C KGK VQ+P C DP+ F L N VC VCG W G+GC+C
Sbjct 3979 ASICLYCRAHVPHPSMDGYCKFKGKCVQVPIGCL-DPIRFCLENNVCNVCGCWLGHGCAC 4037
Query 4361 DQLREPLMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKT 4420
D+ +QS D S +LNR G SAARL PC GT D RAFDIYN+ V+ K LK
Sbjct 4038 DR---TTIQSVDIS-YLNRARGSSAARLEPC-NGTDIDKCVRAFDIYNKNVSFLGKCLKM 4092
Query 4421 NCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMV 4480
NC RF+ D L D YFV+KR T S +HE+++YNL+ A+A HDFF ++ +
Sbjct 4093 NCVRFKNAD----LKDGYFVIKRCTKSVMEHEQSMYNLLNFSGALAEHDFFTWKDGRVIY 4148
Query 4481 PHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDI 4540
++SR LTKYTM DLVYA+R+FDE NCD LKE+LV CCD+ YF+ K WYD VEN DI
Sbjct 4149 GNVSRHNLTKYTMMDLVYAMRNFDEQNCDVLKEVLVLTGCCDNSYFDSKGWYDPVENEDI 4208
Query 4541 LRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGV 4600
RVYA+LG+ V +++LK V CDAM G+VGVLTLDNQDLNGN+YDFGDFV P GV
Sbjct 4209 HRVYASLGKIVARAMLKCVALCDAMVAKGVVGVLTLDNQDLNGNFYDFGDFVVSLPNMGV 4268
Query 4601 PIVDSYYSLLMPILTLTRALAAESHMDADL-AKPLIKWDLLKYDFTEERLCLFDRYFKYW 4659
P SYYS +MPI+ LT LA+E + +D+ +DLLKYDFTE + LF++YFK+W
Sbjct 4269 PCCTSYYSYMMPIMGLTNCLASECFVKSDIFGSDFKTFDLLKYDFTEHKENLFNKYFKHW 4328
Query 4660 DQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRE 4719
YHPNC +C DD C++HCANFN LF+T P T+FGPL RK+F+DGVP V + GYHF++
Sbjct 4329 SFDYHPNCSDCYDDMCVIHCANFNTLFATTIPGTAFGPLCRKVFIDGVPLVTTAGYHFKQ 4388
Query 4720 LGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTV 4779
LG+V N+DVN HS RL+ ELL + DP++ AS L+D+RT CFSVAAL+ + Q V
Sbjct 4389 LGLVWNKDVNTHSVRLTITELLQFVTDPSLIIASSPALVDQRTICFSVAALSTGLTNQVV 4448
Query 4780 KPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLL 4839
KPG+FN++FY+F +GFF EGS + LKHFFFAQ+G+AA+ D+D+YRYN PT+ DI Q
Sbjct 4449 KPGHFNEEFYNFLRLRGFFDEGSELTLKHFFFAQNGDAAVKDFDFYRYNKPTILDICQAR 4508
Query 4840 FVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAY 4899
++V +YFD Y+GGCI A +V+V NL+KSAG+P NK+GKA LYY+S+SYE+QDALFA
Sbjct 4509 VTYKIVSRYFDIYEGGCIKACEVVVTNLNKSAGWPLNKFGKASLYYESISYEEQDALFAL 4568
Query 4900 TKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIG 4959
TKRNV+PT+TQ+NLKYAIS K RARTV GVS+ STMT RQ+HQK LKSI TR ATVVIG
Sbjct 4569 TKRNVLPTMTQLNLKYAISGKERARTVGGVSLLSTMTTRQYHQKHLKSIVNTRNATVVIG 4628
Query 4960 TSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSH 5019
T+KFYGGW+NML+T+ VE P LMGWDYPKCDRA+PNM+R+++++VL KH CC +
Sbjct 4629 TTKFYGGWNNMLRTLIDGVENPMLMGWDYPKCDRALPNMIRMISAMVLGSKHVNCCTATD 4688
Query 5020 RFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLST 5079
RFYRL NE AQVL+E+V G Y KPGGT+SGDA+TAYANS+FNI QAV++N+N LLS
Sbjct 4689 RFYRLGNELAQVLTEVVYSNGGFYFKPGGTTSGDASTAYANSIFNIFQAVSSNINRLLSV 4748
Query 5080 DGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNY 5139
+ + VR+LQ RLY+ YR V+ F+D++Y YLRKHFSMMILSDD VVCYN +Y
Sbjct 4749 PSDSCNNVNVRDLQRRLYDNCYRLTSVEESFIDDYYGYLRKHFSMMILSDDGVVCYNKDY 4808
Query 5140 AAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLP 5199
A G +A I FKA LYYQNNVFMS +KCW E DLTKGPHEFCSQHTM + D YLP
Sbjct 4809 AELGYIADISAFKATLYYQNNVFMSTSKCWVEEDLTKGPHEFCSQHTMQIVDKDGTYYLP 4868
Query 5200 YPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRK 5259
YPDPSRIL AG FVDD+VKTD +++ER+VSLAIDAYPL+KHPN EY VF++ L +++
Sbjct 4869 YPDPSRILSAGVFVDDVVKTDAVVLLERYVSLAIDAYPLSKHPNSEYRKVFYVLLDWVKH 4928
Query 5260 LHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGA 5319
L+ L +L+ +SV L ++ ++W +FY +MY T+LQA G CV+C SQT LRCG
Sbjct 4929 LNKNLNEGVLESFSVTLLDNQEDKFWCEDFYASMYENSTILQAAGLCVVCGSQTVLRCGD 4988
Query 5320 CIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPP 5379
C+R+P LC KC YDHV T HK +L++ PYVCNA GC V+DV +LYLGG++YYC +HKP
Sbjct 4989 CLRKPMLCTKCAYDHVFGTDHKFILAITPYVCNASGCGVSDVKKLYLGGLNYYCTNHKPQ 5048
Query 5380 ISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETL 5439
+SFPLC+ G +FGLYKN+ GS +V FN +AT DWT+ DY LAN + L+LFAAET+
Sbjct 5049 LSFPLCSAGNIFGLYKNSATGSLDVEVFNRLATSDWTDVRDYKLANDVKDTLRLFAAETI 5108
Query 5440 KATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEY 5499
KA EE+ K SY AT++EV+ +EL LSWE GK +PPLNRN VFT ++++K+SK QIGE+
Sbjct 5109 KAKEESVKSSYAFATLKEVVGPKELLLSWESGKVKPPLNRNSVFTCFQISKDSKFQIGEF 5168
Query 5500 TFEKGDYG-DAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLN 5558
FEK +YG D V Y+ T T KL G FVLTSH V PL APT+ QE Y I L+P N
Sbjct 5169 IFEKVEYGSDTVTYKSTVTTKLVPGMIFVLTSHNVQPLRAPTIANQEKYSSIYKLHPAFN 5228
Query 5559 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDAL 5618
+SD +++ V YQ +G QK +T+QGPPG+GKSH +IGL LYYP ARIV+ AC+HAAVD+L
Sbjct 5229 VSDAYANLVPYYQLIGKQKITTIQGPPGSGKSHCSIGLGLYYPGARIVFVACAHAAVDSL 5288
Query 5619 CEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEIS 5678
C KA+ IDKC+RIIPARARVEC+ FK N+T QY+F TVNALPE ADIVV DE+S
Sbjct 5289 CAKAMTVYSIDKCTRIIPARARVECYSGFKPNNTSAQYIFSTVNALPECNADIVVVDEVS 5348
Query 5679 MATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMF 5738
M TNYDLSV+N RL KH VY+GDP QLPAPR ++TKG +EP +N V + M IGPD+F
Sbjct 5349 MCTNYDLSVINQRLSYKHIVYVGDPQQLPAPRVMITKGVMEPVDYNVVTQRMCAIGPDVF 5408
Query 5739 LGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVR 5798
L C RCPAEIV+TVS LVY+NK K S QCFK+F+KG + D S+INR Q+ +V+
Sbjct 5409 LHKCYRCPAEIVNTVSELVYENKFVPVKPASKQCFKVFFKGNVQVDNGSSINRKQLEIVK 5468
Query 5799 EFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCN 5858
FL +NP+W KAVFISPYNSQN VAS+ LGL QTVDSSQGSEYDYVI+ QT++TAH+CN
Sbjct 5469 LFLVKNPSWSKAVFISPYNSQNYVASRFLGLQIQTVDSSQGSEYDYVIYAQTSDTAHACN 5528
Query 5859 VNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIIT 5918
VNRFNVAITRAK GI C+M D+ L+D L+F ++ A L + V GLFK+C++
Sbjct 5529 VNRFNVAITRAKKGIFCVMCDKTLFDSLKFFEIK-----HADLHSSQVCGLFKNCTRTPL 5583
Query 5919 GLHPTQAPTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITR 5978
L PT A T LS+ +FKT G G TY +IS MGF+ + + G ++F TR
Sbjct 5584 NLPPTHAHTFLSLSDQFKTTGDLAVQIGSNNVCTYEHVISFMGFRFDISIPGSHSLFCTR 5643
Query 5979 EEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRV 6038
+ AIR+VR W+G DVE H D +GTN+PLQ+GFS GVN V G V T V
Sbjct 5644 DFAIRNVRGWLGMDVESAHVCGDNIGTNVPLQVGFSNGVNFVVQTEGCVSTNFGDVIKPV 5703
Query 6039 NAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMK 6098
AK PPG+QF+HLIPL+ KG PW +VR +IVQM+SD L LSD +VFVLWA ELT+M+
Sbjct 5704 CAKSPPGEQFRHLIPLLRKGQPWLIVRRRIVQMISDYLSNLSDILVFVLWAGSLELTTMR 5763
Query 6099 YFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSN 6158
YFVKIGP + C C ATC+++ S+ Y C+ H++G DYVYNP+ D+QQWG+ G+L N
Sbjct 5764 YFVKIGPIKYC-YCGNSATCYNSVSNEYCCFKHALGCDYVYNPYAFDIQQWGYVGSLSQN 5822
Query 6159 HDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMV 6218
H C +H N H AS DA+MTRCLAVH+CFVK VDW+V YP I +E +N R VQ V
Sbjct 5823 HHTFCNIHRNEHDASGDAVMTRCLAVHDCFVKNVDWTVTYPFIANEKFINGCGRNVQGHV 5882
Query 6219 VKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDK 6278
V++AL K V+HDIGNPK ++C + +W YD QP + ++ L Y YATH
Sbjct 5883 VRAALKLYKPSVIHDIGNPKGVRCA-VTDAKWYCYDKQPVNSN---VKLLDYDYATHGQ- 5937
Query 6279 FTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAF 6338
DG+CLFWNCNVD YP +IVCRFDTR S NL G +GGSLYVNKHAFHTPA+DK AF
Sbjct 5938 -LDGLCLFWNCNVDMYPEFSIVCRFDTRTRSVFNLEGVNGGSLYVNKHAFHTPAYDKRAF 5996
Query 6339 TNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLD 6398
LK +PFFY+ DS C+ V ++YVPL++++C+TRCN+GGAVC HAN Y++Y++
Sbjct 5997 VKLKPMPFFYFDDSDCDV----VQEQVNYVPLRASSCVTRCNIGGAVCSKHANLYQKYVE 6052
Query 6399 AYNMMISAGFSLWIYKQFDTYNLWNTF--TRLQSLENVAYNVVNKGHFDGHAGEAPVSII 6456
AYN AGF++W+ FD YNLW F T LQSLEN+A+NVV KG F G GE PV+++
Sbjct 6053 AYNTFTQAGFNIWVPHSFDVYNLWQIFIETNLQSLENIAFNVVKKGCFTGVDGELPVAVV 6112
Query 6457 NNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWD 6516
N+ V+ + +D +F NKTTLP NVAFEL+AKR + P + IL NLGV V+WD
Sbjct 6113 NDKVFVRYGDVDNLVFTNKTTLPTNVAFELFAKRKMGLTPPLSILKNLGVVATYKFVLWD 6172
Query 6517 YKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGS 6576
Y+ E P T VC TD + V FD ++G + F N VL +
Sbjct 6173 YEAERPFTSYTKSVCKYTDF--------NEDVCVCFDNSIQGSYERFTLTTNAVLFSTVV 6224
Query 6577 VKGLTPSKGPAQASVNGVTLIG-------ESVKTQFNYFKKVDGIIQQLPETYFTQSRDL 6629
+K LTP K +NG+ + E + + Y +K +G Q + ++TQ R+L
Sbjct 6225 IKNLTPIK-LNFGMLNGMPVSSIKGDKGVEKLVNWYIYVRK-NGQFQDHYDGFYTQGRNL 6282
Query 6630 EDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQD 6689
DF PRS ME DFL + M FI +Y LE + FEH+VYGD S LGGLHL+I + S+
Sbjct 6283 SDFTPRSDMEYDFLNMDMGVFINKYGLEDFNFEHVVYGDVSKTTLGGLHLLISQFRLSKM 6342
Query 6690 SPLKLEDFIP-MDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVK 6748
LK +DF+ D+T++ +T SSK VC+ +DLLLDDFV I+KS DL VISKV +
Sbjct 6343 GVLKADDFVTASDTTLRCCTVTYLNELSSKVVCTYMDLLLDDFVTILKSLDLGVISKVHE 6402
Query 6749 VTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGEN 6808
V ID +MLWCKD H+ TFYP+LQ+++ W+ G AMP +YK+QRM LE C+L NYG
Sbjct 6403 VIIDNKPYRWMLWCKDNHLSTFYPQLQSAE-WKCGYAMPQIYKLQRMCLEPCNLYNYGAG 6461
Query 6809 AVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGT 6868
+P GIM+NV KYTQLCQYLN+ T+ VP+NMRV+H+GAGSDKGVAPGT VL++WLP
Sbjct 6462 IKLPSGIMLNVVKYTQLCQYLNSTTMCVPHNMRVLHYGAGSDKGVAPGTTVLKRWLPPDA 6521
Query 6869 LLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYL 6928
+++D+D+ND+VSDAD ++ GDCATV+ +K+DL+ISDMYD R K EN SK+GFFTYL
Sbjct 6522 IIIDNDINDYVSDADFSITGDCATVYLEDKFDLLISDMYDGRIKFCDGENVSKDGFFTYL 6581
Query 6929 CGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLG 6988
G I++KLA+GGS+A+KITE+SWN LY+L+ F++WT F T+VN SSSEAFLIG NYLG
Sbjct 6582 NGVIREKLAIGGSVAIKITEYSWNKYLYELIQRFAFWTLFCTSVNTSSSEAFLIGINYLG 6641
Query 6989 KPKEQ--IDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMI 7046
+ I G T+HANYIFWRN+ + LS S+ D+SKF K + T V++LK++ +NDM+
Sbjct 6642 DFIQGPFIAGNTVHANYIFWRNSTIMSLSYNSVLDLSKFECKHKATVVVTLKDSDVNDMV 6701
Query 7047 YSLLEKGRLIIRENNRVVVSSDILVNN 7073
SL++ GRL++R N R S+ LV+
Sbjct 6702 LSLIKSGRLLLRNNGRFGGFSNHLVST 6728
Score = 234 bits (596), Expect = 4e-59, Method: Composition-based stats.
Identities = 118/655 (18%), Positives = 220/655 (34%), Gaps = 99/655 (15%)
Query 1227 NKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSG----DITCVVIPSKKA 1282
LL + + ++ L+ ++ + P VG + ++ VV P
Sbjct 1291 ENLLHGGGVARAIDILTEGQLQSLSKDYISSNGPLKVGAGVMLECEKFNVFNVVGPRTG- 1349
Query 1283 GGTTEMLSRALKKVPVDEYITTYP--GQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAK 1340
+L A + + I P G G +E ++ L S N
Sbjct 1350 KHEHSLLVEAYNSILFENGIPLMPLLSCGIFGVRIE----------NSLKALFSCDINKP 1399
Query 1341 EEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFF 1400
++ S + +L + P+ DV + K ++ D GV
Sbjct 1400 LQVFVYSSNEEQAVLKFLDGLDLT-PVIDDVDVV------KPFRVEGNFSFFDCGV---- 1448
Query 1401 YTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRS-----LKAPAVVSVSS 1455
N+L+ + + + L++ + + + L+ A+ +++
Sbjct 1449 --------------NALDGDIYLL---FTNSILMLDKQGQLLDTKLNGILQQAALDYLAT 1491
Query 1456 PDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTL 1515
V N K E + + S D S+ V L R V +
Sbjct 1492 VKTVPAGNL-----VKLFVESCTIYMCVVPSINDLSFDKNLGRC-VRKLNRLKTCVIANV 1545
Query 1516 -------------ESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVD 1562
V+F ++ V+ ++ + + + T D N+ +V+
Sbjct 1546 PAIDVLKKLLSSLTLTVKFVVESNVMDVNDC------FKNDNVVLKITEDGINVKDVVVE 1599
Query 1563 MSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGR 1622
S + G+Q G DG D + EG + + DT+ S A E F
Sbjct 1600 SSKSLGKQLGVVS-DGVD--------SFEG---VLPINTDTVLSVAPEVDWVAFYGFEKA 1647
Query 1623 YMSALNHTKKWKFP--QVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR 1680
+ A K + +P VGG + DNNC++++ + LQ L+ F + L + +
Sbjct 1648 ALFASLDVKPYGYPNDFVGGFRVLGTTDNNCWVNATCIILQYLKPTFKSKGLNVLWNKFV 1707
Query 1681 AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT 1740
GD F + I + + G+ GD E ++ L ++ L S V C +T+
Sbjct 1708 TGDVGPFVSFIYFITMSSKGQKGDAEEALSKLSEY--LISDSIVTLEQYSTCDICKSTVV 1765
Query 1741 GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC 1800
V++ + ++ LK G + R + V+ + V+++ Q L
Sbjct 1766 EVKSAIVCASV----LKDGCDVGFCPHRHKLRSRVKFVNGRVVITNVGEPIISQPSKLLN 1821
Query 1801 ANEYT---GNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTT 1852
YT G++ GHY A DGA L VT + T+
Sbjct 1822 GIAYTTFSGSFDNGHYVVYDAANN-AVYDGARLFSSDLSTLAVTAIVVVGGCVTS 1875
Score = 164 bits (416), Expect = 3e-38, Method: Composition-based stats.
Identities = 91/408 (22%), Positives = 147/408 (36%), Gaps = 40/408 (10%)
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
+ + S + D D + I + YQ
Sbjct 1157 FQKGECCICHKMQTYKLVSMKGTGVFVQDPAPIDIDAFPVKPICSSVYLGVKGSGHYQTN 1216
Query 961 PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC 1020
F + + V + ++ +T +++ V F + NV
Sbjct 1217 LYSFNKAIDGFGVFDI--KNSSVNTVCFVDVDFHSVEIEAGEVKPFA----VYKNVKFYL 1270
Query 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
DI + +VNAAN +L HGGGVA A++ T G +Q S DYI NGPL VG
Sbjct 1271 GDISHLVNCVSFDFVVNAANENLLHGGGVARAIDILTEGQLQSLSKDYISSNGPLKVGAG 1330
Query 1081 CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL 1140
+L +VVGP E L++A I L PLLS GIFG + SL
Sbjct 1331 VMLECEKF--NVFNVVGPRTGKHEHSLLVEAYNSILFENGIPLMPLLSCGIFGVRIENSL 1388
Query 1141 Q---VCVQTVRTQVYIAVNDKALYEQVVMDYLD--NLKPRVEAPKQEEPPNTEDSKTEEK 1195
+ C QV++ +++ EQ V+ +LD +L P ++ +P E + +
Sbjct 1389 KALFSCDINKPLQVFVYSSNE---EQAVLKFLDGLDLTPVIDDVDVVKPFRVEGNFSFF- 1444
Query 1196 SVVQKPVDVKPKIKACIDEVTTTLEETKFL--TNKLLLFADINGKLYHDSQNMLRGEDMS 1253
D L+ +L TN +L+ L +L+ +
Sbjct 1445 -----------------DCGVNALDGDIYLLFTNSILMLDKQGQLLDTKLNGILQQAALD 1487
Query 1254 FLEKDAPYMVGDV----ITSGDITCVVIPSKKAGGTTEMLSRALKKVP 1297
+L G++ + S I V+PS + L R ++K+
Sbjct 1488 YLATVKTVPAGNLVKLFVESCTIYMCVVPSINDLSFDKNLGRCVRKLN 1535
Score = 78.9 bits (193), Expect = 2e-12, Method: Composition-based stats.
Identities = 51/263 (19%), Positives = 93/263 (35%), Gaps = 30/263 (11%)
Query 1617 ESFLGRYMSALNHTKKWKFPQVG--GLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQE 1674
E L+ + + F G+ + +DNNC++S+ L+ LQ ++ ++ +Q
Sbjct 1026 EQPFEEVEHVLSIKQPFSFSFRDELGVRVLDQSDNNCWISTTLVQLQLTKLLDDSIEMQL 1085
Query 1675 AYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQ 1734
+ G + S+ G LGD + ++ LL+ S + C CG+
Sbjct 1086 ----FKVGKVDSIVQKCYELSHLISGSLGDSGKLLSELLKEKYTCSIT--FEMSCD-CGK 1138
Query 1735 KTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAP-PAEYKL 1793
K G ++ + G C+C + T LV + + V + P P +
Sbjct 1139 KFDDQVG---CLFWIMPYTKLFQKG--ECCICHKMQTYKLVSMKGTGVFVQDPAPIDIDA 1193
Query 1794 QQGTFLCANEYTGNYQCGHY---THITAK--ETLYRIDGAHLTKMSEYKGPVTDVFY--- 1845
+C++ Y G GHY + K + D + S DV +
Sbjct 1194 FPVKPICSSVYLGVKGSGHYQTNLYSFNKAIDGFGVFD---IKNSSVNTVCFVDVDFHSV 1250
Query 1846 ----KETSYTTTIKPVSYKLDGV 1864
E K V + L +
Sbjct 1251 EIEAGEVKPFAVYKNVKFYLGDI 1273
Score = 57.0 bits (136), Expect = 9e-06, Method: Composition-based stats.
Identities = 42/179 (23%), Positives = 56/179 (31%), Gaps = 30/179 (17%)
Query 179 GGAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEI 238
G +VD CG DG P+ + E DY + +++
Sbjct 108 GAGSVVFVDKYMCGFDGKPVLP------------KNMWEFRDYFNNNTDSIVIGGVTYQL 155
Query 239 AWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMG 298
AW R D SYE Q I+S T K+ +P K G
Sbjct 156 AWDVIRKDLSYEQQNVLAIESIHYLGTT-----GHTLKSGCKLTNAKPPKYSSKVV-LSG 209
Query 299 RIRSVY-PVASPQECNNMHL----------STLMKCNHCDEVSWQTCDFLKATCEHCGT 346
+VY SP N M L + +KCN C SW + CGT
Sbjct 210 EWNAVYRAFGSPFITNGMSLLDIIVKPVFFNAFVKCN-CGSESWSVGAWDGYLSSCCGT 267
>sp|P0C6X1|R1AB_CVH22 Replicase polyprotein 1ab OS=Human coronavirus
229E OX=11137 GN=rep PE=1 SV=1
Length=6758
Score = 6769 bits (17563), Expect = 0.0, Method: Composition-based stats.
Identities = 2252/5038 (45%), Positives = 3113/5038 (62%), Gaps = 180/5038 (4%)
Query 2077 VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKR 2136
V+ T+ + S+ G + + H ++ ++ + YV P N
Sbjct 1859 VDKGHYTVYDTAKKSMYDGDRFV-KHDLSLLSVTSVVMVGGYVAPVNTVKPKPVINQLDE 1917
Query 2137 LAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVK 2196
AQ+ F ++ ++ T+ S + + T + VK +AK G+ +
Sbjct 1918 KAQKFF-DFGDFLIHNFVIFFTWLLSMFTLCK----TAVTTGDVKIMAKAPQRTGVVLKR 1972
Query 2197 SPKFSKLFTIAM-----WLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSS 2251
S K++ + A+ WLL L LI + +L FG ++C+ Y S
Sbjct 1973 SLKYNLKASAAVLKSKWWLLAKFTKLLLLIYTLYSVVLLCVRFGPFNFCSETVNGYAKS- 2031
Query 2252 NVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISS--------YKLDLTILGLAAE 2303
N D+C+GS C +CL G L + L+ + I+ + + + +L
Sbjct 2032 NFVKDDYCDGSLGCKMCLFGYQELSQFSHLDVVWKHITDPLFSNMQPFIVMVLLLIFGDN 2091
Query 2304 WVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIF 2363
++ ++L+ ++ + + + VF GY ++ WF+ P + +
Sbjct 2092 YLRCFLLY----FVAQMISTVGVFLGYKETN--------WFL----HFIPFDVICDELLV 2135
Query 2364 FASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCK 2423
+ H++ GC + C+ C K R R TIVNG++RSFYV ANGG FCK
Sbjct 2136 TVIVIKVISFVRHVLFGCENPDCIACSKSARLKRFPVNTIVNGVQRSFYVNANGGSKFCK 2195
Query 2424 THNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFD 2483
H + C++CD++ GSTFI+ EV+R+L K + PT + ++D V +NG LY
Sbjct 2196 KHRFFCVDCDSYGYGSTFITPEVSRELGNITKTNVQPTGPAYVMIDKVEFENGFYRLYSC 2255
Query 2484 KAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMC 2543
+ + S + + + N + IVF+ + + K+ASVY+SQL+C
Sbjct 2256 ETFWRYNFDITESKYSCKEVFKNCNV----LDDFIVFNNNGT-NVTQVKNASVYFSQLLC 2310
Query 2544 QPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVAL 2603
+PI L+D L+S + S + + + AY+D +F L A ++ A + A G+++
Sbjct 2311 RPIKLVDSELLSTL--SVDFNGVLHKAYIDVLRNSFGKD---LNANMSLAECKRALGLSI 2365
Query 2604 DGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVE-NMTP 2662
+ + +H D+ ++ S NNF+ +Y K E ++
Sbjct 2366 SD--------------------HEFTSAISNAHRCDVLLSDLSFNNFVSSYAKPEEKLSA 2405
Query 2663 RDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCA 2722
DL C+ A+ +NA V ++W+ KD+ SLS + RK I +K + F LT
Sbjct 2406 YDLACCMRAGAKVVNANVLTKDQTPIVWHAKDFNSLSAEGRKYIVKTSKAKGLTFLLTIN 2465
Query 2723 TTRQVVNVITTKISLKGGKI--VSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYT 2780
+ V + T I K G + L L L+C++ +C+ MP I +
Sbjct 2466 ENQAVTQIPATSIVAKQGAGDAGHSLTWLWLLCGLVCLIQFYLCFF-MPYFMYDIVSSF- 2523
Query 2781 NEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGS-YKNDKSCPVVAAIITREI 2839
E +K I++G ++ + C N F+ W + G N +SCP+V + EI
Sbjct 2524 -EGYDFKYIENGQLKNFEAPLKCVRNVFENFEDWHYAKFGFTPLNKQSCPIVVGV--SEI 2580
Query 2840 GFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIF 2899
V G+P V + G L F + +CY + C+ + CT
Sbjct 2581 VNTVAGIPSNVY--LVGKTLIFTLQAAFGNAGVCYD-----IFGVTTPEKCIFTSACTRL 2633
Query 2900 KDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDA 2958
+ G V YCY+T L+EGS+ YS ++ + Y +G+ I+ P +G R V T
Sbjct 2634 EGLGGNNV-YCYNTALMEGSLPYSSIQANAYYKYDNGNFIKLPEVIAQGFGFRTVRTIAT 2692
Query 2959 EYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGAL 3018
+YCR G C S G+C +W +N+ R +G CG NL+ NI +
Sbjct 2693 KYCRVGECVESNAGVCFGFD-KWFVNDG--RVANGYVCGTGLWNLVFNILSMFSSSFSVA 2749
Query 3019 DVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFL 3078
+S ++ + + KFRR+FG+ + ++ ++ + +V
Sbjct 2750 AMSGQILLNCALGAFAIFCCFLVTKFRRMFGDLSVG-VCTVVVAVLLNNVSYIVTQNLVT 2808
Query 3079 PGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYL 3138
Y++ Y + T +++ + + P+W+ A Y + +
Sbjct 2809 MIAYAILYFFATRSL--RYAWIWCAAYLIAYISFAPWWLCAWYFLAMLTGLLPSLLKLKV 2866
Query 3139 RKRVMFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGA 3197
+F G F TFE AA TF+++ Y KL + + + Y A YN+YKY+SG
Sbjct 2867 STN-LFEGDKFVGTFESAAAGTFVIDMRSYEKLANS--ISPEKLKSYAASYNRYKYYSGN 2923
Query 3198 LDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3257
+ YR A +LAKA+ DFS D+LY PP S S LQ+G RKMA PSG VE C+
Sbjct 2924 ANEADYRCACYAYLAKAMLDFSRDHNDILYTPPTVSYGST-LQAGLRKMAQPSGFVEKCV 2982
Query 3258 VQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRV 3317
V+V G T LNGLWL D VYCPRHVI + +Y+ H+F + +G L V
Sbjct 2983 VRVCYGNTVLNGLWLGDIVYCPRHVIASNTT-SAIDYDHEYSIMRLHNFSIISGTAFLGV 3041
Query 3318 IGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIK 3377
+G +M L++KV +N TP++ F ++ G+ F++LACY+G GV+ MR N TI+
Sbjct 3042 VGATMHGVTLKIKVSQTNMHTPRHSFRTLKSGEGFNILACYDGCAQGVFGVNMRTNWTIR 3101
Query 3378 GSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTD 3437
GSF+NG+CGS G+N+ V F YMH +EL +G H G+ +G YG F D+ Q +
Sbjct 3102 GSFINGACGSPGYNLKNGEVEFVYMHQIELGSGSHVGSSFDGVMYGGFEDQPNLQVESAN 3161
Query 3438 TTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQT 3497
+T+NV+A+LYAA++NG W+L + +N A + + + D L+A+T
Sbjct 3162 QMLTVNVVAFLYAAILNGCTWWLKGEKLFVEHYNEWAQANGFTAMNGE--DAFSILAAKT 3219
Query 3498 GIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ-GKFKKIVKGT 3556
G+ V + A++ +L NG G+ ILG + L DEF+ +VV+Q GV Q GK + K
Sbjct 3220 GVCVERLLHAIQ-VLNNGFGGKQILGYSSLNDEFSINEVVKQMFGVNLQSGKTTSMFKSI 3278
Query 3557 HHWM-LLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCL 3615
+ + L + +T W V PF + ++A++ C +VKHK FL +
Sbjct 3279 SLFAGFFVMFWAELFVYTTTIW-----VNPGFLTPFMILLVALSLCLTFVVKHKVLFLQV 3333
Query 3616 FLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTAR 3675
FLLPS+ A N + V +++ + S+ ++ V L + +L T R
Sbjct 3334 FLLPSIIVAAIQNCAWD--YHVTKVLAEKFDYNVSVMQMDIQGFVNIFICLFVALLHTWR 3391
Query 3676 TVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARA- 3734
+ L ++I ++Y Y +S+ +++ SN + I + R
Sbjct 3392 FAKERCTHWCTYLFSLIAVLYTALYSY---DYVSLLVMLLCAISNEWYIGAIIFRICRFG 3448
Query 3735 IVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVST 3794
+ F+ VEY + ++ ++L Y LG+ C Y+GL +NR+ + TLGVYD+ VS
Sbjct 3449 VAFLPVEYVSY----FDGVKTVLLFYMLLGFVSCMYYGLLYWINRFCKCTLGVYDFCVSP 3504
Query 3795 QEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQ 3854
EF+YM + GL P DA L+ KL+GIGG IKV+TVQSK++D+KCT+VVL+ +L
Sbjct 3505 AEFKYMVANGLNAPNGPFDALFLSFKLMGIGGPRTIKVSTVQSKLTDLKCTNVVLMGILS 3564
Query 3855 QLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDN 3914
+ + S+SK WA CV++HN I L D A E +++LL+ LS + L + +N
Sbjct 3565 NMNIASNSKEWAYCVEMHNKINLCDDPETAQELLLALLAFFLSKHSDFGLGDLVDSYFEN 3624
Query 3915 RATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAM 3974
+ LQ++AS F +PS+ AY TA++ YE AVANG S ++K+LKK++NVAK+EFDR++++
Sbjct 3625 DSILQSVASSFVGMPSFVAYETARQEYENAVANGSSPQIIKQLKKAMNVAKAEFDRESSV 3684
Query 3975 QRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCV 4034
Q+K+ +MA+QA MYK+AR+ ++++KV SAM ++LF MLR+LD +++ I+N AR+G V
Sbjct 3685 QKKINRMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNMARNGVV 3744
Query 4035 PLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD 4094
PL++IP T+AA+L+VVVPD+ ++ YA +W +Q+V D D K V L ++ +
Sbjct 3745 PLSVIPATSAARLVVVVPDHDSFVKMMVDGFVHYAGVVWTLQEVKDNDGKNVHLKDVTKE 3804
Query 4095 NSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKG 4154
N L WPLI+T R VKLQNNE+ P ++ + ++ NAL YNN G
Sbjct 3805 NQEILVWPLILTCER---VVKLQNNEIMPGKMKVKATKGEGDGGITSEGNAL--YNNEGG 3859
Query 4155 GRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNL 4214
F+ A ++ +K+ ++ G T+ ELEPPCRFV DTP GP++KYLYF+K LNNL
Sbjct 3860 RAFMYAYVTTKPGMKYVKWEHDSGVVTV--ELEPPCRFVIDTPTGPQIKYLYFVKNLNNL 3917
Query 4215 NRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKM 4274
RG VLG + ATVRLQAG TE +NS +L+ C+FAVDPA AY D + G +P+ NCVKM
Sbjct 3918 RRGAVLGYIGATVRLQAGKQTEFVSNSHLLTHCSFAVDPAAAYLDAVKQGAKPVGNCVKM 3977
Query 4275 LCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCA 4334
L +G+GQAIT T ++N Q+++GGAS C+YCR H+ HP GFC KGK+VQ+P
Sbjct 3978 LTNGSGSGQAITCTIDSNTTQDTYGGASVCIYCRAHVAHPTMDGFCQYKGKWVQVPIG-T 4036
Query 4335 NDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSAARLTPCGTG 4394
NDP+ F L NTVC VCG W +GC+CD+ +QS D S +LNRV G SAARL PC G
Sbjct 4037 NDPIRFCLENTVCKVCGCWLNHGCTCDR---TAIQSFDNS-YLNRVRGSSAARLEPC-NG 4091
Query 4395 TSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEET 4454
T D RAFD+YN+ + K LK+NC RF+ D++ D++++VKR S HE++
Sbjct 4092 TDIDYCVRAFDVYNKDASFIGKNLKSNCVRFKNVDKD----DAFYIVKRCIKSVMDHEQS 4147
Query 4455 IYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEI 4514
+YNL+K C AVA HDFF + + ++SRQ LTKYTM DL +ALR+FDE +C+ KEI
Sbjct 4148 MYNLLKGCNAVAKHDFFTWHEGRTIYGNVSRQDLTKYTMMDLCFALRNFDEKDCEVFKEI 4207
Query 4515 LVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVL 4574
LV CC DYF K+W+D +EN DI RVYA LG+ V ++LK V FCD M G+VGVL
Sbjct 4208 LVLTGCCSTDYFEMKNWFDPIENEDIHRVYAALGKVVANAMLKCVAFCDEMVLKGVVGVL 4267
Query 4575 TLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADL-AKP 4633
TLDNQDLNGN+YDFGDFV PG G+P SYYS +MP++ +T LA+E M +D+ +
Sbjct 4268 TLDNQDLNGNFYDFGDFVLCPPGMGIPYCTSYYSYMMPVMGMTNCLASECFMKSDIFGQD 4327
Query 4634 LIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPT 4693
+DLLKYDFTE + LF++YFKYW Q YHP+C++C D+ CILHC+NFN LF+T P T
Sbjct 4328 FKTFDLLKYDFTEHKEVLFNKYFKYWGQDYHPDCVDCHDEMCILHCSNFNTLFATTIPNT 4387
Query 4694 SFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAAS 4753
+FGPL RK+F+DGVP V + GYHF++LG+V N+DVN HS+RL+ ELL + DP + AS
Sbjct 4388 AFGPLCRKVFIDGVPVVATAGYHFKQLGLVWNKDVNTHSTRLTITELLQFVTDPTLIVAS 4447
Query 4754 GNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQ 4813
L+DKRT CFSVAAL+ + QTVKPG+FNK+FYDF S+GFF EGS + LKHFFF Q
Sbjct 4448 SPALVDKRTVCFSVAALSTGLTSQTVKPGHFNKEFYDFLRSQGFFDEGSELTLKHFFFTQ 4507
Query 4814 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGF 4873
G+AAI D+DYYRYN PTM DI Q +V +YFDCY+GGCI + +V+V NL+KSAG+
Sbjct 4508 KGDAAIKDFDYYRYNRPTMLDIGQARVAYQVAARYFDCYEGGCITSREVVVTNLNKSAGW 4567
Query 4874 PFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICS 4933
P NK+GKA LYY+S+SYE+QDA+F+ TKRN++PT+TQ+NLKYAIS K RARTV GVS+ +
Sbjct 4568 PLNKFGKAGLYYESISYEEQDAIFSLTKRNILPTMTQLNLKYAISGKERARTVGGVSLLA 4627
Query 4934 TMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDR 4993
TMT RQFHQK LKSI ATR ATVVIGT+KFYGGW NMLK + +DV+ P LMGWDYPKCDR
Sbjct 4628 TMTTRQFHQKCLKSIVATRNATVVIGTTKFYGGWDNMLKNLMADVDDPKLMGWDYPKCDR 4687
Query 4994 AMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGD 5053
AMP+M+R++++++L KH TCC S +FYRL+NE AQVL+E+V G Y KPGGT+SGD
Sbjct 4688 AMPSMIRMLSAMILGSKHVTCCTASDKFYRLSNELAQVLTEVVYSNGGFYFKPGGTTSGD 4747
Query 5054 ATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDE 5113
ATTAYANSVFNI QAV++N+N +LS + + + V+ LQ +LY+ YRN +VD FVD+
Sbjct 4748 ATTAYANSVFNIFQAVSSNINCVLSVNSSNCNNFNVKKLQRQLYDNCYRNSNVDESFVDD 4807
Query 5114 FYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETD 5173
FY YL+KHFSMMILSDD+VVCYN YA G +A I FKA LYYQN VFMS AKCWTE D
Sbjct 4808 FYGYLQKHFSMMILSDDSVVCYNKTYAGLGYIADISAFKATLYYQNGVFMSTAKCWTEED 4867
Query 5174 LTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAI 5233
L+ GPHEFCSQHTM + + YLPYPDPSRI+ AG FVDDI KTD +++ER+VSLAI
Sbjct 4868 LSIGPHEFCSQHTMQIVDENGKYYLPYPDPSRIISAGVFVDDITKTDAVILLERYVSLAI 4927
Query 5234 DAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAM 5293
DAYPL+KHP EY VF+ L +++ L+ L +L+ +SV L +++ S++W+ FY +M
Sbjct 4928 DAYPLSKHPKPEYRKVFYALLDWVKHLNKTLNEGVLESFSVTLLDEHESKFWDESFYASM 4987
Query 5294 YTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNA 5353
Y TVLQA G CV+C SQT LRCG C+RRP LC KC YDHV T HK +L++ PYVCN
Sbjct 4988 YEKSTVLQAAGLCVVCGSQTVLRCGDCLRRPMLCTKCAYDHVFGTDHKFILAITPYVCNT 5047
Query 5354 PGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATC 5413
GC+V DVT+LYLGG++YYC HKP +SFPLC+ G VFGLYK++ +GS ++ FN ++T
Sbjct 5048 SGCNVNDVTKLYLGGLNYYCVDHKPHLSFPLCSAGNVFGLYKSSALGSMDIDVFNKLSTS 5107
Query 5414 DWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKP 5473
DW++ DY LAN E L+LFAAET+KA EE+ K SY AT++E++ +EL L WE GK
Sbjct 5108 DWSDIRDYKLANDAKESLRLFAAETVKAKEESVKSSYAYATLKEIVGPKELLLLWESGKA 5167
Query 5474 RPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYG-DAVVYRGTTTYKLNVGDYFVLTSHT 5532
+PPLNRN VFT +++TK+SK Q+GE+ FEK DYG D V Y+ T T KL G F+LTSH
Sbjct 5168 KPPLNRNSVFTCFQITKDSKFQVGEFVFEKVDYGSDTVTYKSTATTKLVPGMLFILTSHN 5227
Query 5533 VMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHF 5592
V PL APT+ QE Y I L+P+ N+SD +++ V YQ +G Q+ +T+QGPPG+GKSH
Sbjct 5228 VAPLRAPTMANQEKYSTIYKLHPSFNVSDAYANLVPYYQLIGKQRITTIQGPPGSGKSHC 5287
Query 5593 AIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNST 5652
+IG+ +YYP ARIV+TACSHAAVD+LC KA+ +DKC+RIIPARARVEC+ FK N+
Sbjct 5288 SIGIGVYYPGARIVFTACSHAAVDSLCAKAVTAYSVDKCTRIIPARARVECYSGFKPNNN 5347
Query 5653 LEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTL 5712
QYVF TVNALPE ADIVV DE+SM TNYDLSV+N R+ KH VY+GDP QLPAPR L
Sbjct 5348 SAQYVFSTVNALPEVNADIVVVDEVSMCTNYDLSVINQRISYKHIVYVGDPQQLPAPRVL 5407
Query 5713 LTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQC 5772
++KG +EP +N V + M IGPD+FL C RCPAEIV+TVS LVY+NK K+ S QC
Sbjct 5408 ISKGVMEPIDYNVVTQRMCAIGPDVFLHKCYRCPAEIVNTVSELVYENKFVPVKEASKQC 5467
Query 5773 FKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQ 5832
FK+F +G + D S+INR Q+ VV+ F+ +N W KAVFISPYNSQN VA+++LGL TQ
Sbjct 5468 FKIFERGSVQVDNGSSINRRQLDVVKRFIHKNSTWSKAVFISPYNSQNYVAARLLGLQTQ 5527
Query 5833 TVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLE 5892
TVDS+QGSEYDYVIF QT++TAH+CN NRFNVAITRAK GI CIMSDR L+D L+F +
Sbjct 5528 TVDSAQGSEYDYVIFAQTSDTAHACNANRFNVAITRAKKGIFCIMSDRTLFDALKFFEIT 5587
Query 5893 IPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIPKDMT 5952
+ LQ+E+ GLFKDC++ L P+ A T+LS+ +FKT G G T
Sbjct 5588 MT-----DLQSESSCGLFKDCARNPIDLPPSHATTYLSLSDRFKTSGDLAVQIGNNNVCT 5642
Query 5953 YRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLG 6012
Y +IS MGF+ + + G ++F TR+ A+RHVR W+G DVEG H T D VGTN+PLQ+G
Sbjct 5643 YEHVISYMGFRFDVSMPGSHSLFCTRDFAMRHVRGWLGMDVEGAHVTGDNVGTNVPLQVG 5702
Query 6013 FSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQML 6072
FS GV+ VA P G V T + V A+ PPG+QF H++PL+ KG PW+V+R +IVQM+
Sbjct 5703 FSNGVDFVAQPEGCVLTNTGSVVKPVRARAPPGEQFTHIVPLLRKGQPWSVLRKRIVQMI 5762
Query 6073 SDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHS 6132
+D L G SD +VFVLWA G ELT+M+YFVKIG + C C ATC+++ S+ Y C+ H+
Sbjct 5763 ADFLAGSSDVLVFVLWAGGLELTTMRYFVKIGAVKHC-QCGTVATCYNSVSNDYCCFKHA 5821
Query 6133 VGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRV 6192
+G DYVYNP++ID+QQWG+ G+L +NH C VH N HVAS DAIMTRCLAV++CFVK V
Sbjct 5822 LGCDYVYNPYVIDIQQWGYVGSLSTNHHAICNVHRNEHVASGDAIMTRCLAVYDCFVKNV 5881
Query 6193 DWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKF 6252
DWS+ YP+I +E +N R VQ ++++A+ +HDIGNPK I+C + +W
Sbjct 5882 DWSITYPMIANENAINKGGRTVQSHIMRAAIKLYNPKAIHDIGNPKGIRCA-VTDAKWYC 5940
Query 6253 YDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLN 6312
YD P + +E Y Y TH DG+CLFWNCNVD YP +IVCRFDTR S LN
Sbjct 5941 YDKNPINSNVKTLE---YDYMTHGQ--MDGLCLFWNCNVDMYPEFSIVCRFDTRTRSTLN 5995
Query 6313 LPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKS 6372
L G +GGSLYVN HAFHTPA+DK A LK PFFYY D CE V ++YVPL++
Sbjct 5996 LEGVNGGSLYVNNHAFHTPAYDKRAMAKLKPAPFFYYDDGSCEV----VHDQVNYVPLRA 6051
Query 6373 ATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFT--RLQS 6430
CIT+CN+GGAVC HAN YR Y+++YN+ AGF++W+ FD YNLW TFT LQ
Sbjct 6052 TNCITKCNIGGAVCSKHANLYRAYVESYNIFTQAGFNIWVPTTFDCYNLWQTFTEVNLQG 6111
Query 6431 LENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKR 6490
LEN+A+NVVNKG F G GE PV+I + V+ + D +F NKT+LP N+AFEL+AKR
Sbjct 6112 LENIAFNVVNKGSFVGADGELPVAISGDKVFVRDGNTDNLVFVNKTSLPTNIAFELFAKR 6171
Query 6491 NIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTV 6550
+ P + IL NLGV V+WDY+ E P T VC TD A +
Sbjct 6172 KVGLTPPLSILKNLGVVATYKFVLWDYEAERPLTSFTKSVCGYTDFA--------EDVCT 6223
Query 6551 LFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKT------- 6603
+D ++G + F + N VL + +VK T K +N L G ++ T
Sbjct 6224 CYDNSIQGSYERFTLSTNAVLFSATAVK--TGGKSLPAIKLNFGMLNGNAIATVKSEDGN 6281
Query 6604 -----QFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEG 6658
F Y +K DG + ++TQ R+L+DF PRS ME DFL + + FIQ+Y LE
Sbjct 6282 IKNINWFVYVRK-DGKPVDHYDGFYTQGRNLQDFLPRSTMEEDFLNMDIGVFIQKYGLED 6340
Query 6659 YAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFI-PMDSTVKNYFITDAQTGSS 6717
+ FEH+VYGD S LGGLHL+I + S+ LK E+F+ D T+K +T SS
Sbjct 6341 FNFEHVVYGDVSKTTLGGLHLLISQVRLSKMGILKAEEFVAASDITLKCCTVTYLNDPSS 6400
Query 6718 KCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQAS 6777
K VC+ +DLLLDDFV ++KS DL+V+SKV +V ID +MLWCKD V TFYP+LQ++
Sbjct 6401 KTVCTYMDLLLDDFVSVLKSLDLTVVSKVHEVIIDNKPWRWMLWCKDNAVATFYPQLQSA 6460
Query 6778 QAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVP 6837
+ W+ G +MP +YK QRM LE C+L NYG +P GIM NV KYTQLCQY N+ TL VP
Sbjct 6461 E-WKCGYSMPGIYKTQRMCLEPCNLYNYGAGLKLPSGIMFNVVKYTQLCQYFNSTTLCVP 6519
Query 6838 YNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTAN 6897
+NMRV+H GAGSD GVAPGTAVL++WLP ++VD+D+ D+VSDAD ++ GDCATV+ +
Sbjct 6520 HNMRVLHLGAGSDYGVAPGTAVLKRWLPHDAIVVDNDVVDYVSDADFSVTGDCATVYLED 6579
Query 6898 KWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYK 6957
K+DL+ISDMYD RTK + EN SKEGFFTY+ GFI +KLA+GGSIA+K+TE+SWN LY+
Sbjct 6580 KFDLLISDMYDGRTKAIDGENVSKEGFFTYINGFICEKLAIGGSIAIKVTEYSWNKKLYE 6639
Query 6958 LMGHFSWWTAFVTNVNASSSEAFLIGANYLGKPKEQ--IDGYTMHANYIFWRNTNPIQLS 7015
L+ FS+WT F T+VN SSSEAF++G NYLG + IDG +HANY+FWRN+ + LS
Sbjct 6640 LVQRFSFWTMFCTSVNTSSSEAFVVGINYLGDFAQGPFIDGNIIHANYVFWRNSTVMSLS 6699
Query 7016 SYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
S+ D+SKF K + T V+ LK++ IN+M+ SL+ G+L++R N + + S+ LV+
Sbjct 6700 YNSVLDLSKFNCKHKATVVVQLKDSDINEMVLSLVRSGKLLVRGNGKCLSFSNHLVST 6757
Score = 275 bits (703), Expect = 1e-71, Method: Composition-based stats.
Identities = 133/733 (18%), Positives = 248/733 (34%), Gaps = 78/733 (11%)
Query 1155 VNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTED--SKTEEKSVVQKPVDVKPKIKACI 1212
A Y V + +K V+ +EE E + +V DV +
Sbjct 1237 CIKDADYNAKVEISVTPIKNTVDTTPKEEFVVKEKLNAFLVHDNVAFYQGDVDTVVNGVD 1296
Query 1213 DEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVIT---- 1268
+ L + L ++ L+ + VG +
Sbjct 1297 FDFIVNAAN-----ENLAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTGVMVECD 1351
Query 1269 SGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSA 1328
S I VV P +K ++L +A + +E T G + +T+L+
Sbjct 1352 SLRIFNVVGP-RKGKHERDLLIKAYNTIN-NEQGTPLTPILSCGIFGIKLETSLEVLLDV 1409
Query 1329 FYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQ 1388
+ + + V + ++ + + + ++ I+ + +
Sbjct 1410 CNTKEVKVFVYTDTEVCKVKDFVSGLVNVQKVEQPKI-----EPKPVSVIK-----VAPK 1459
Query 1389 EGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAP 1448
VD +F ++ + +P+V + L++ + +
Sbjct 1460 PYRVDGKFSYF-------TEDLLCVADD--KPIVL----FTDSMLTLDDRGLALDN-ALS 1505
Query 1449 AVVSVSSPDAVTTYNGYLTSS--SKTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKR 1506
V+S + D V N + S K V + + S +D K
Sbjct 1506 GVLSAAIKDCVDI-NKAIPSGNLIKFDIGSVVVYMCVVPSEKDKHLDNNVQRCT---RKL 1561
Query 1507 GDKIVYHTLESPVEFHLDGEVLSLDKLKSL---LSLREVKTIKVFTTVDNTNLHTQLVDM 1563
+ P ++ L + SL S L E K I + T D N+H V
Sbjct 1562 NRLMCDIVCTIPADYILPLVLSSLTCNVSFVGELKAAEAKVITIKVTEDGVNVHDVTVTT 1621
Query 1564 SMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFE---YYHTLDESFL 1620
++ QQ G D++ P + + D + F+ + T+D S
Sbjct 1622 DKSFEQQVGVIADKDKDLSGAVPSDLNTSELLTKAIDVDWVEFYGFKDAVTFATVDHSAF 1681
Query 1621 GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR 1680
++ V G+ +K +DNNC++++V +ALQ + F + L A+ +
Sbjct 1682 A-----------YESAVVNGIRVLKTSDNNCWVNAVCIALQYSKPHFISQGLDAAWNKFV 1730
Query 1681 AGDAANFCALILAYSNKTVGELGDVRETMTHLLQH-ANLESAKRVLNVVCKHCGQK-TTT 1738
GD F A + + G+ GD +T+T L ++ AN + C C K +
Sbjct 1731 LGDVEIFVAFVYYVARLMKGDKGDAEDTLTKLSKYLANEAQVQLEHYSSCVECDAKFKNS 1790
Query 1739 LTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSA----PPAEYKLQ 1794
+ + + + ++ D ++ G CV G + +++S P A+ +L
Sbjct 1791 VASINSAIVCASVKRDGVQVGY---CVHGIKYYSRVRSVRGRAIIVSVEQLEPCAQSRLL 1847
Query 1795 QGTFLCANEYTGNYQCGHYT-HITAKETLYRIDGAHLTKMSEYKGPVTDVF----YKETS 1849
G A ++G GHYT + TAK+++ DG K VT V Y
Sbjct 1848 SGVAYTA--FSGPVDKGHYTVYDTAKKSM--YDGDRFVKHDLSLLSVTSVVMVGGYVAPV 1903
Query 1850 YTTTIKPVSYKLD 1862
T KPV +LD
Sbjct 1904 NTVKPKPVINQLD 1916
Score = 177 bits (448), Expect = 6e-42, Method: Composition-based stats.
Identities = 114/580 (20%), Positives = 211/580 (36%), Gaps = 58/580 (10%)
Query 985 TTEQSEIEPEPEPTPEEP--VNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIH 1042
+ I+ + TP+E V + + DNVA D+ + IVNAAN +
Sbjct 1248 EISVTPIKNTVDTTPKEEFVVKEKLNAFLVHDNVAFYQGDVDTVVNGVDFDFIVNAANEN 1307
Query 1043 LKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNA 1102
L HGGG+A AL+ T G +Q+ S ++I L G + VG ++ +L + +VVGP
Sbjct 1308 LAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTGVMVECDSL--RIFNVVGPRKGK 1365
Query 1103 GEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT---QVYIAVNDKA 1159
E L+KA N Q L P+LS GIFG K SL+V + T +V++ + +
Sbjct 1366 HERDLLIKAYNTINNEQGTPLTPILSCGIFGIKLETSLEVLLDVCNTKEVKVFVYTDTEV 1425
Query 1160 LYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTL 1219
+ + L N++ +VE PK E P V KP V K + E +
Sbjct 1426 CKVKDFVSGLVNVQ-KVEQPKIEPKP------VSVIKVAPKPYRVDGKF-SYFTEDLLCV 1477
Query 1220 EETK---FLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSG----DI 1272
+ K T+ +L D L + +L ++ + G++I +
Sbjct 1478 ADDKPIVLFTDSMLTLDDRGLALDNALSGVLSAAIKDCVDINKAIPSGNLIKFDIGSVVV 1537
Query 1273 TCVVIPSKKAGGTTEMLSRALKKVPV------------DEYITTYPGQGCAGYTLEEAKT 1320
V+PS+K + R +K+ C + E K
Sbjct 1538 YMCVVPSEKDKHLDNNVQRCTRKLNRLMCDIVCTIPADYILPLVLSSLTCNVSFVGELKA 1597
Query 1321 ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLA-HAEETRKLMPICMDVRAIM-ATI 1378
A K + + ++A ++ +P ++ ++ I
Sbjct 1598 AEAKVITIKVTEDGVNVHDVTVTTDKSFEQQVGVIADKDKDLSGAVPSDLNTSELLTKAI 1657
Query 1379 QRKYKGI-----KIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGY----- 1428
+ + VD+ + + + T N+ V + + Y
Sbjct 1658 DVDWVEFYGFKDAVTFATVDHSAFAYESAVVNGIRVLKTSDNNCWVNAVCIALQYSKPHF 1717
Query 1429 VTHGFNLEEAARCMRSLK--APAVVSVS---------SPDAVTTYNGYLTSSSKTSEEHF 1477
++ G + + ++ V V+ + D +T + YL + ++ EH+
Sbjct 1718 ISQGLDAAWNKFVLGDVEIFVAFVYYVARLMKGDKGDAEDTLTKLSKYLANEAQVQLEHY 1777
Query 1478 VETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLES 1517
V +++ S + + + +KR V + +
Sbjct 1778 SSCVECDAKFKN-SVASINSAIVCASVKRDGVQVGYCVHG 1816
Score = 97.8 bits (242), Expect = 4e-18, Method: Composition-based stats.
Identities = 51/269 (19%), Positives = 95/269 (35%), Gaps = 24/269 (9%)
Query 1634 KFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILA 1693
F ++ GL +K DNNC+++SV+L +Q + A+Q + G A
Sbjct 1037 PFEELNGLKILKQLDNNCWVNSVMLQIQLTGILDGDYAMQF----FKMGRVAKMIERCYT 1092
Query 1694 YSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSY 1753
G +GDV M LL+ +L + V++ C + V
Sbjct 1093 AEQCIRGAMGDVGLCMYRLLK--DLHTGFMVMDYKCSCTSGRLEESGAVLFCTPTKK--- 1147
Query 1754 DNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTF--LCANEYTGNYQCG 1811
C + Q + + + + P +C++ + G CG
Sbjct 1148 ---AFPYGTCLNCNAPRMCTIRQLQGTIIFVQQKPEPVNPVSFVVKPVCSSIFRGAVSCG 1204
Query 1812 HYTHITAKETLYRIDGAHLTKM------SEYKGPVTDVFYKETSYTTTIKPVSYKLDGVT 1865
HY + L +DG + K+ + + D Y ++ P+ +D
Sbjct 1205 HYQTNIYSQNL-CVDGFGVNKIQPWTNDALNTICIKDADY-NAKVEISVTPIKNTVDTTP 1262
Query 1866 YTE--IEPKLDGYYKKDNAYYTEQPIDLV 1892
E ++ KL+ + DN + + +D V
Sbjct 1263 KEEFVVKEKLNAFLVHDNVAFYQGDVDTV 1291
Score = 47.4 bits (111), Expect = 0.007, Method: Composition-based stats.
Identities = 37/179 (21%), Positives = 59/179 (33%), Gaps = 31/179 (17%)
Query 176 ELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHE 235
+ GG VT Y D CG DG P+ L + +D+ H
Sbjct 107 KRGGGNVT-YTDQYLCGADGKPV------------MSEDLWQFVDHFGENE-EIIINGHT 152
Query 236 HEIAWFTERSDKSYEHQTPFEIKSA--KKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKT 293
+ AW T+R Y+ Q I+ D V + +VK K
Sbjct 153 YVCAWLTKRKPLDYKRQNNLAIEEIEYVHGDALHTLRNGSVLEMAKEVKT----SSKVVL 208
Query 294 EGFMGRIRSVYPVASPQECNNM--------HLSTLMKCNHCDEVSWQTCD--FLKATCE 342
+ ++ V+ +N+ +S L++C C SW D K++C
Sbjct 209 SDALDKLYKVFGSPVMTNGSNILEAFTKPVFISALVQCT-CGTKSWSVGDWTGFKSSCC 266
Score = 46.6 bits (109), Expect = 0.014, Method: Composition-based stats.
Identities = 69/490 (14%), Positives = 149/490 (30%), Gaps = 76/490 (16%)
Query 528 SVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSL-RLVDAMVY 586
+V PL F G F T+ + +L+ A + + D I+E L +D +
Sbjct 587 AVYKPLFAFNVNVMGTRPEKFPTTV-----TCENLESAVLFVNDKITEFQLDYSIDVIDN 641
Query 587 TSDLLTNSVIIMAYVTGGLVQQTSQWLSNLLGTT-----VEKLRPIFEWIEAKLSAGVEF 641
+ N + + V + + + + + +A + A
Sbjct 642 EIIVKPNISLCVPLYVRDYVDKWDDFCRQYSNESWFEDDYRAFISVLDITDAAVKAAESK 701
Query 642 ---------------LKDAWEILKFLITGVFDI------------VKGQIQVASDNIKDC 674
+ D +I +I V + +G + + K
Sbjct 702 AFVDTIVPPCPSILKVIDGGKIWNGVIKNVNSVRDWLKSLKLNLTQQGLLGTCAKRFKRW 761
Query 675 VKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLLMPLK 734
+ ++ N L+ + V I G ++ + +I + + + + + L P
Sbjct 762 LGILLEAYNAFLDTVVSTVKIGGLTFKTYAFDKPYIVIRDIVCKVENKTEAEWIELFPHN 821
Query 735 APKEV-----TFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLM 789
+ + + T EEV L + E F G ++ +
Sbjct 822 DRIKSFSTFESAYMPIADPTHFDIEEVELLDAE----------FVEPGCGGILAVIDEHV 871
Query 790 LLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGYKNVRITFEL-D 847
+ KD Y S G F G V+F +D V +++ V++ FE D
Sbjct 872 FYK-KDGVYYP--SNGTNILPVAFTKAAGG---KVSFSDDVEVKDIEPVYRVKLCFEFED 925
Query 848 ERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFY 907
E++ V + + + + L V N+ T+Y
Sbjct 926 EKLVDVCEKAIG-----KKIKHEGDWDSFCKTIQSALS-VVSCYVNLP---------TYY 970
Query 908 LFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGAS 967
++D+ G + S + S +P ++ + ++ + + ++
Sbjct 971 IYDEEGGNDLSLPVMISEWPLSVQQAQQEATLPDIAEDVVDQVEEVNSIFDIETVDVKHD 1030
Query 968 AETVRVEEEE 977
+ EE
Sbjct 1031 VSPFEMPFEE 1040
>sp|P0C6Y5|R1AB_CVPPU Replicase polyprotein 1ab OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=rep PE=1 SV=1
Length=6684
Score = 6757 bits (17531), Expect = 0.0, Method: Composition-based stats.
Identities = 2221/4986 (45%), Positives = 3043/4986 (61%), Gaps = 177/4986 (4%)
Query 2142 FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAK--LCLDAGINYVKSPK 2199
F Y F ++ + + K K L V++
Sbjct 1821 FGRYADMFFMAGDKILRLLLEVFKYLLVLFMCLRSTKMPKVKVKPPLAFKDFGAKVRTLN 1880
Query 2200 FSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFC 2259
+ + + L + + + CNG + Y NSS + + C
Sbjct 1881 YMRQLNKPSVWRYAKLVLLLIAIYNFFYLFVSIPVVHKLTCNGAVQAYKNSSFIKSA-VC 1939
Query 2260 EGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLG 2319
S C CL+ D L + L+ +K D L L+Y F F
Sbjct 1940 GNSILCKACLASYDELADFQHLQVTW----DFKSDPLWNRLVQ---LSYFAFLAVFG--- 1989
Query 2320 LSAIMQVFFGYFASHFISNSWLMWF-------IISIVQMAPVSAMVRMYIFFASFYYIWK 2372
+ ++ F YF S ++ N WL +F + +V +SA + + K
Sbjct 1990 -NNYVRCFLMYFVSQYL-NLWLSYFGYVEYSWFLHVVNFESISAEFVIVVIVVKAVLALK 2047
Query 2373 SYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNC 2432
HI+ C++ +C C + R TR+ +VNG ++ YV+ANG FCK HN+ C NC
Sbjct 2048 ---HIVFACSNPSCKTCSRTARQTRIPIQVVVNGSMKTVYVHANGTGKFCKKHNFYCKNC 2104
Query 2433 DTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLY---------FD 2483
D++ +TFI DE+ RDLS K+ + TD+S V V +G Y +D
Sbjct 2105 DSYGFENTFICDEIVRDLSNSVKQTVYATDRSHQEVTKVECSDGFYRFYVGDEFTSYDYD 2164
Query 2484 KAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMC 2543
+K + L + LD+ + GS NV ++A VY+SQL+
Sbjct 2165 VKHKKYSSQEVLKSMLLLDDFIVYSPSGSALANV--------------RNACVYFSQLIG 2210
Query 2544 QPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVAL 2603
+PI +++ L+ D+ S + +F+A + +F+V + + K L E + L
Sbjct 2211 KPIKIVNSDLLEDL--SVDFKGALFNAKKNVIKNSFNVDVSECKNL-----DECYRACNL 2263
Query 2604 DGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKV--ENMT 2661
+ STF A +H + +T S NNF + K ++
Sbjct 2264 NVSFSTFEMAVNN------------------AHRFGILITDRSFNNFWPSKVKPGSSGVS 2305
Query 2662 PRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTC 2721
D+G C+ +A+ +NA+V S++W +D+ +LS +K + + + F LT
Sbjct 2306 AMDIGKCMTSDAKIVNAKVLTQRGKSVVWLSQDFAALSSTAQKVLVKTFVEEGVNFSLTF 2365
Query 2722 ATTRQVVNVI----TTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHD 2777
++ T +S K G + + +L + +C + +
Sbjct 2366 NAVGSDDDLPYERFTESVSPKSGSGFFDVITQLKQIVILVFVFIFICGLCSVYSVATQSY 2425
Query 2778 GYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKN-DKSCPVVAA-II 2835
+ E Y I++G+ + T C N + GF WF + G KSCP+V +
Sbjct 2426 IESAEGYDYMVIKNGIVQPFDDTISCVHNTYKGFGDWFKAKYGFIPTFGKSCPIVVGTVF 2485
Query 2836 TREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAE 2895
E +P +P V +I G L F V N+CY + D CV
Sbjct 2486 DLENMRPIPDVPAYV--SIVGRSLVFAINAAFGVTNMCYDHTGNAVSKDSYFDTCVFNTA 2543
Query 2896 CTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTT 2955
CT G + YC L+EG+ YS+L PD Y G++++ P +R V T
Sbjct 2544 CTTLTGLGGT-IVYCAKQGLVEGAKLYSDLMPDYYYEHASGNMVKLPAIIRGLGLRFVKT 2602
Query 2956 FDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPV 3015
YCR G C S+ G C +V +NE +G CG + N+F +
Sbjct 2603 QATTYCRVGECIDSKAGFCFGGDNWFVYDNEF---GNGYICGNSVLGFFKNVFKLFNSNM 2659
Query 3016 GALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAY 3075
+ S +++ IIA L Y +KF+++FG+ ++ ++ L+ + V
Sbjct 2660 SVVATSGAMLVNIIIACLAIAMCYGVLKFKKIFGDCTFLIVM-IIVTLVVNNVSYFVTQN 2718
Query 3076 SFLPGVYSVFYLYLTFYFTNDVSFLAHLQ--WFAMFSPIVPFWITAIYVFCISLKHCHWF 3133
+F +Y++ Y ++ T +++ L + + + P+++ Y+
Sbjct 2719 TFFMIIYAIVY----YFITRKLAYPGILDAGFIIAYINMAPWYVITAYILVFLYDSLPSL 2774
Query 3134 FNNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYK 3192
F + +F G F FE AA+ TF+++ Y + + T + + Y +NKYK
Sbjct 2775 FKLKVSTN-LFEGDKFVGNFESAAMGTFVIDMRSYETIVNST--SIARIKSYANSFNKYK 2831
Query 3193 YFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGK 3252
Y++G++ YR A HL KAL D+S + D+LY PP S+ S LQSG RKMA PSG
Sbjct 2832 YYTGSMGEADYRMACYAHLGKALMDYSVNRTDMLYTPPTVSVNST-LQSGLRKMAQPSGL 2890
Query 3253 VEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGN 3312
VE C+V+V+ G LNGLWL D V CPRHVI + + NYE+ + H+F V N
Sbjct 2891 VEPCIVRVSYGNNVLNGLWLGDEVICPRHVIASDTTRV-INYENEMSSVRLHNFSVSKNN 2949
Query 3313 VQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRP 3372
V L V+ + L LKV+ NP TP++KF I+ G++F++LACY G P VY MR
Sbjct 2950 VFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIKAGESFNILACYEGCPGSVYGVNMRS 3009
Query 3373 NHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQ 3432
TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++ EG+ YG + D+ + Q
Sbjct 3010 QGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLELGNGSHVGSNFEGEMYGGYEDQPSMQ 3069
Query 3433 AAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGP 3492
GT+ + NV+A+LYAA+ING+RWF+ + +L +N A ++ L+ D
Sbjct 3070 LEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSLESYNTWAKTNSFTELSS--TDAFSM 3127
Query 3493 LSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ-GKFKK 3551
L+A+TG +V + ++ L G GRTIL L DEFTP +V+RQ GV Q GK K
Sbjct 3128 LAAKTGQSVEKLLDSIVRL-NKGFGGRTILSYGSLCDEFTPTEVIRQMYGVNLQAGKVKS 3186
Query 3552 IVKGTHHWMLLTFLTSLLIL-VQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLL-VKHK 3609
+ ++T +T L ++ ++ F ++ F+ L + + + + +KHK
Sbjct 3187 FF-----YPIMTAMTILFAFWLEFFMYTPFTWINP-TFVSIVLAVTTLISTVFVSGIKHK 3240
Query 3610 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLL 3669
F F+LPS+ V N+ + S+ + + +E +T ++ ++ ++
Sbjct 3241 MLFFMSFVLPSVILVTAHNL-FWDFSYYESLQSIVENTNTMFLPVDMQGVMLTVFCFIVF 3299
Query 3670 ILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQA----------ISMWALVISVTS 3719
+ + R + + ++ + V D+ ++M +++S+T+
Sbjct 3300 VTYSVRFFTCKQSWFSLAVTTILVIFNMVKIFGTSDEPWTENQIAFCFVNMLTMIVSLTT 3359
Query 3720 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3779
VV +A IV + ++CI +VY GY CCY+G+ +NR
Sbjct 3360 KDWMVVIASYRIAYYIVVCVM--PSAFVSDFGFMKCISIVYMACGYLFCCYYGILYWVNR 3417
Query 3780 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3839
+ +T GVY + VS E +YM + L PK++ DA L+ KL+G+GGK IK++TVQSK+
Sbjct 3418 FTCMTCGVYQFTVSAAELKYMTANNLSAPKNAYDAMILSAKLIGVGGKRNIKISTVQSKL 3477
Query 3840 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3899
+++KCT+VVLL +L ++ VES+SK W CV LHN+I L D EK+++L++ LS
Sbjct 3478 TEMKCTNVVLLGLLSKMHVESNSKEWNYCVGLHNEINLCDDPEIVLEKLLALIAFFLSKH 3537
Query 3900 GAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3959
D++ L E +N LQ++AS +++LPS+ A A+ E+A N S +LK+L K
Sbjct 3538 NTCDLSELIESYFENTTILQSVASAYAALPSWIALEKARADLEEAKKNDVSPQILKQLTK 3597
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
+ N+AKS+F+R+A++Q+KL+KMA+QA MYK+AR+ D+++K+ SAM ++LF ML+KLD
Sbjct 3598 AFNIAKSDFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDM 3657
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
++N II+ AR+G +PL+IIP +A +L+V+ P + N YA A+W I +V
Sbjct 3658 SSVNTIIDQARNGVLPLSIIPAASATRLVVITPSLEVFSKIRQENNVHYAGAIWTIVEVK 3717
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4139
DA+ V L E+ N NL WPL +T R KLQNNE+ P L++ + A T
Sbjct 3718 DANGSHVHLKEVTAANELNLTWPLSITCERT---TKLQNNEIMPGKLKERAVRASATLDG 3774
Query 4140 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4199
+ A + G F+ A ++ +LK+ ++ + I ELE P RF D G
Sbjct 3775 EAFGSGKALMASESGKSFMYAFIASDNNLKYVKWESN--NDIIPIELEAPLRFYVDGANG 3832
Query 4200 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4259
P+VKYLYF+K LN L RG VLG + ATVRLQAG TE P+NS++L+ CAF+ DPAKAY D
Sbjct 3833 PEVKYLYFVKNLNTLRRGAVLGYIGATVRLQAGKPTEHPSNSSLLTLCAFSPDPAKAYVD 3892
Query 4260 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4319
+ G QP+ NCVKML G G A+T EAN Q+S+GGAS C+YCRCH++HP G
Sbjct 3893 AVKRGMQPVNNCVKMLSNGAGNGMAVTNGVEANTQQDSYGGASVCIYCRCHVEHPAIDGL 3952
Query 4320 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
C KGK+VQIPT DP+ F + N VC VCG W GC CD R + ++LNR
Sbjct 3953 CRYKGKFVQIPTG-TQDPIRFCIENEVCVVCGCWLNNGCMCD--RTSMQSFTVDQSYLNR 4009
Query 4380 VCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYF 4439
V G SAARL PC GT D V RAFDIYN+ VA KFLKTNC RF+ D+ D+Y+
Sbjct 4010 VRGSSAARLEPC-NGTDPDHVSRAFDIYNKDVACIGKFLKTNCSRFRNLDKH----DAYY 4064
Query 4440 VVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYA 4499
+VKR T + HE+ YN +KD AVA HDFF ++ +++R+ LTKYTM DL YA
Sbjct 4065 IVKRCTKTVMDHEQVCYNDLKDSGAVAEHDFFTYKEGRCEFGNVARRNLTKYTMMDLCYA 4124
Query 4500 LRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTV 4559
+R+FDE NC+ LKEILVT C +++F KDW+D VEN I VYA LG V ++LK V
Sbjct 4125 IRNFDEKNCEVLKEILVTVGACTEEFFENKDWFDPVENEAIHEVYAKLGPIVANAMLKCV 4184
Query 4560 QFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRA 4619
FCDA+ + G +GV+TLDNQDLNGN+YDFGDFV+ APG G V SYYS +MP++ +T
Sbjct 4185 AFCDAIVEKGYIGVITLDNQDLNGNFYDFGDFVKTAPGFGCACVTSYYSYMMPLMGMTSC 4244
Query 4620 LAAESHMDADL-AKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILH 4678
L +E+ + +D+ ++DLL YDFTE + LF +YFKYWD+TYHPNC +C D CI+H
Sbjct 4245 LESENFVKSDIYGSDYKQYDLLAYDFTEHKEYLFQKYFKYWDRTYHPNCSDCTSDECIIH 4304
Query 4679 CANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFK 4738
CANFN LFS P T+FGPLVRK+ +DGVP VV+ GYHF++LG+V N DV L + +LS
Sbjct 4305 CANFNTLFSMTIPMTAFGPLVRKVHIDGVPVVVTAGYHFKQLGIVWNLDVKLDTMKLSMT 4364
Query 4739 ELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFF 4798
+LL + DP + AS LLD+RT CFS+AAL+ + +QTVKPG+FNKDFYDF +GFF
Sbjct 4365 DLLRFVTDPTLLVASSPALLDQRTVCFSIAALSTGITYQTVKPGHFNKDFYDFITERGFF 4424
Query 4799 KEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCIN 4858
+EGS + LKHFFFAQ G AA++D++YYRYN T+ DI Q FV ++V KYF+CYDGGCIN
Sbjct 4425 EEGSELTLKHFFFAQGGEAAMTDFNYYRYNRVTVLDICQAQFVYKIVGKYFECYDGGCIN 4484
Query 4859 ANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAIS 4918
A +V+V N DKSAG+P NK+GKARLYY+++SYE+QDALFA TKRNV+PT+TQMNLKYAIS
Sbjct 4485 AREVVVTNYDKSAGYPLNKFGKARLYYETLSYEEQDALFALTKRNVLPTMTQMNLKYAIS 4544
Query 4919 AKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDV 4978
K RARTV GVS+ STMT RQ+HQK LKSIAATR ATVVIG++KFYGGW NMLK + DV
Sbjct 4545 GKARARTVGGVSLLSTMTTRQYHQKHLKSIAATRNATVVIGSTKFYGGWDNMLKNLMRDV 4604
Query 4979 ETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMC 5038
+ LMGWDYPKCDRA+PNM+R+ ++++L KH CC + RFYRL+NE AQVL+E+V C
Sbjct 4605 DNGCLMGWDYPKCDRALPNMIRMASAMILGSKHVGCCTHNDRFYRLSNELAQVLTEVVHC 4664
Query 5039 GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYE 5098
G Y KPGGT+SGD TTAYANS FNI QAV+ANVN LL D N + V+++Q ++Y+
Sbjct 4665 TGGFYFKPGGTTSGDGTTAYANSAFNIFQAVSANVNKLLGVDSNACNNVTVKSIQRKIYD 4724
Query 5099 CLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQ 5158
YR+ +D EFV E+++YLRKHFSMMILSDD VVCYN +YA G VA I FKA LYYQ
Sbjct 4725 NCYRSSSIDEEFVVEYFSYLRKHFSMMILSDDGVVCYNKDYADLGYVADINAFKATLYYQ 4784
Query 5159 NNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVK 5218
NNVFMS +KCW E DL+ GPHEFCSQHT+ + D YLPYPDPSRIL AG FVDDIVK
Sbjct 4785 NNVFMSTSKCWVEPDLSVGPHEFCSQHTLQIVGPDGDYYLPYPDPSRILSAGVFVDDIVK 4844
Query 5219 TDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTN 5278
TD +M+ER+VSLAIDAYPLTKHP Y VF+ L +++ L L +LD +SV +
Sbjct 4845 TDNVIMLERYVSLAIDAYPLTKHPKPAYQKVFYTLLDWVKHLQKNLNAGVLDSFSVTMLE 4904
Query 5279 DNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVIST 5338
+ ++W EFY ++Y TVLQA G CV+C SQT LRCG C+RRP LC KC YDHV+ T
Sbjct 4905 EGQDKFWSEEFYASLYEKSTVLQAAGMCVVCGSQTVLRCGDCLRRPLLCTKCAYDHVMGT 4964
Query 5339 SHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTC 5398
HK ++S+ PYVC+ GC+V DVT+L+LGG+SYYC +HKP +SFPLCANG VFGLYK++
Sbjct 4965 KHKFIMSITPYVCSFNGCNVNDVTKLFLGGLSYYCMNHKPQLSFPLCANGNVFGLYKSSA 5024
Query 5399 VGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREV 5458
VGS+ V DFN +A DWTN DY LAN E LK+FAAET+KA EE+ K Y A ++EV
Sbjct 5025 VGSEAVEDFNKLAVSDWTNVEDYKLANNVKESLKIFAAETVKAKEESVKSEYAYAVLKEV 5084
Query 5459 LSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYG-DAVVYRGTTT 5517
+ +E+ L WE K +PPLNRN VFT ++++K++K+Q+GE+ FE+ +YG D+V Y+ T+T
Sbjct 5085 IGPKEIVLQWEASKTKPPLNRNSVFTCFQISKDTKIQLGEFVFEQSEYGSDSVYYKSTST 5144
Query 5518 YKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQK 5577
YKL G FVLTSH V PL AP LV QE Y I+ LYP NI++ +++ V YQ +G QK
Sbjct 5145 YKLTPGMIFVLTSHNVSPLKAPILVNQEKYNTISKLYPVFNIAEAYNTLVPYYQMIGKQK 5204
Query 5578 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPA 5637
++T+QGPPG+GKSH IGL LYYP ARIVYTACSHAAVDALCEKA K +D+CSRIIP
Sbjct 5205 FTTIQGPPGSGKSHCVIGLGLYYPQARIVYTACSHAAVDALCEKAAKNFNVDRCSRIIPQ 5264
Query 5638 RARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHY 5697
R RV+C+ FK N+T QY+FCTVNALPE + DIVV DE+SM TNYDLSV+N+RL KH
Sbjct 5265 RIRVDCYTGFKPNNTNAQYLFCTVNALPEASCDIVVVDEVSMCTNYDLSVINSRLSYKHI 5324
Query 5698 VYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALV 5757
VY+GDP QLPAPRTL+ KG L+P+ +N V + M T+GPD+FL C RCPAEIV TVSALV
Sbjct 5325 VYVGDPQQLPAPRTLINKGVLQPQDYNVVTKRMCTLGPDVFLHKCYRCPAEIVKTVSALV 5384
Query 5758 YDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYN 5817
Y+NK +S QCFKMF KG + + +S+IN Q+ VV+ FL NP WRKAVFISPYN
Sbjct 5385 YENKFVPVNPESKQCFKMFVKGQVQIESNSSINNKQLEVVKAFLAHNPKWRKAVFISPYN 5444
Query 5818 SQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIM 5877
SQN VA ++LGL TQTVDS+QGSEYDYVI+TQT++T H+ NVNRFNVAITRAK+GILCIM
Sbjct 5445 SQNYVARRLLGLQTQTVDSAQGSEYDYVIYTQTSDTQHATNVNRFNVAITRAKVGILCIM 5504
Query 5878 SDRDLYDKLQFTSLEIPRRNVATLQAEN-VTGLFKDCSKIITGLHPTQAPTHLSVDIKFK 5936
DR +Y+ L F L+ + LQA+ GLFKDCSK + P A T++S+ FK
Sbjct 5505 CDRTMYENLDFYELKDSKI---GLQAKPETCGLFKDCSKSEQYIPPAYATTYMSLSDNFK 5561
Query 5937 T-EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEG 5995
T +GL V+I KD+ Y +IS MGF+ + GY +F TR+ A+R+VRAW+GFDVEG
Sbjct 5562 TSDGLAVNIG--TKDVKYANVISYMGFRFEANIPGYHTLFCTRDFAMRNVRAWLGFDVEG 5619
Query 5996 CHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLM 6055
H D VGTN+PLQLGFS GV+ V G V TE V A+ PPG+QF HLIPLM
Sbjct 5620 AHVCGDNVGTNVPLQLGFSNGVDFVVQTEGCVITEKGNSIEVVKARAPPGEQFAHLIPLM 5679
Query 6056 YKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKR 6115
KG PW++VR +IVQM+ D GLSD ++FVLWA G ELT+M+YFVKIG + C C K
Sbjct 5680 RKGQPWHIVRRRIVQMVCDYFDGLSDILIFVLWAGGLELTTMRYFVKIGRPQKCE-CGKS 5738
Query 6116 ATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCD 6175
ATC+S+S YAC+ H++G DY+YNP+ ID+QQWG+TG+L NH + C +H N HVAS D
Sbjct 5739 ATCYSSSQSVYACFKHALGCDYLYNPYCIDIQQWGYTGSLSMNHHEVCNIHRNEHVASGD 5798
Query 6176 AIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIG 6235
AIMTRCLA+H+CFVKRVDWS+ YP I +E ++N A R VQ V+K+AL +HD+G
Sbjct 5799 AIMTRCLAIHDCFVKRVDWSIVYPFIDNEEKINKAGRIVQSHVMKAALKIFNPAAIHDVG 5858
Query 6236 NPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYP 6295
NPK I+C + W YD P ++ + L Y Y H +G+ LFWNCNVD YP
Sbjct 5859 NPKGIRCA-TTPIPWFCYDRDPINNN---VRCLDYDYMVHGQ--MNGLMLFWNCNVDMYP 5912
Query 6296 ANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCE 6355
+IVCRFDTR S L+L GC+GG+LYVN HAFHTPA+D+ AF LK +PFFYY DS CE
Sbjct 5913 EFSIVCRFDTRTRSKLSLEGCNGGALYVNNHAFHTPAYDRRAFAKLKPMPFFYYDDSNCE 5972
Query 6356 SHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQ 6415
V +YVPLKS CIT+CN+GGAVC+ HA YR Y++ YN+ + AGF++W +
Sbjct 5973 ----LVDGQPNYVPLKSNVCITKCNIGGAVCKKHAALYRAYVEDYNIFMQAGFTIWCPQN 6028
Query 6416 FDTYNLWNTFTR---LQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIF 6472
FDTY LW+ F LQSLENVA+NVV KG F G G+ P ++I + + + D IF
Sbjct 6029 FDTYMLWHGFVNSKALQSLENVAFNVVKKGAFTGLKGDLPTAVIADKIMVRDGPTDKCIF 6088
Query 6473 ENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCT 6532
NKT+LP NVAFEL+AKR + P + IL NLGV V+WDY+ E P T VC+
Sbjct 6089 TNKTSLPTNVAFELYAKRKLGLTPPLTILRNLGVVATYKFVLWDYEAERPFSNFTKQVCS 6148
Query 6533 MTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVN 6592
TD+ S + FD + G + F R+ VLI+ +VKGL+ K +N
Sbjct 6149 YTDLD--------SEVVTCFDNSIAGSFERFTTTRDAVLISNNAVKGLSAIK-LQYGLLN 6199
Query 6593 GVTL--IGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEF 6650
+ + +G T + Y +K ++Q+ ++Y+TQ R E FKPRS ME DFL + F
Sbjct 6200 DLPVSTVGNKPVTWYIYVRKNGEYVEQI-DSYYTQGRTFETFKPRSTMEEDFLSMDTTLF 6258
Query 6651 IQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFI-PMDSTVKNYFI 6709
IQ+Y LE Y FEH+V+GD S +GG+HL+I + ++ +++F+ DST+K+ I
Sbjct 6259 IQKYGLEDYGFEHVVFGDVSKTTIGGMHLLISQVRLAKMGLFSVQEFMNNSDSTLKSCCI 6318
Query 6710 TDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVET 6769
T A SSK VC+ +D+LLDDFV IIKS DL+V+SKVV V +D +MLWC++ H++T
Sbjct 6319 TYADDPSSKNVCTYMDILLDDFVTIIKSLDLNVVSKVVDVIVDCKAWRWMLWCENSHIKT 6378
Query 6770 FYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYL 6829
FYP+LQ+++ W PG +MP LYK+QRM LE+C+L NYG +P GI NV KYTQLCQYL
Sbjct 6379 FYPQLQSAE-WNPGYSMPTLYKIQRMCLERCNLYNYGAQVKLPDGITTNVVKYTQLCQYL 6437
Query 6830 NTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGD 6889
NT TL VP+ MRV+H GA GVAPG+ VLR+WLP +LVD+DL D+VSDAD ++ GD
Sbjct 6438 NTTTLCVPHKMRVLHLGAAGASGVAPGSTVLRRWLPDDAILVDNDLRDYVSDADFSVTGD 6497
Query 6890 CATVHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEH 6949
C +++ +K+DL++SD+YD TK + EN SK+GFFTY+ GFIK+KL+LGGS+A+KITE
Sbjct 6498 CTSLYIEDKFDLLVSDLYDGSTKSIDGENTSKDGFFTYINGFIKEKLSLGGSVAIKITEF 6557
Query 6950 SWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGK--PKEQIDGYTMHANYIFWR 7007
SWN DLY+L+ F +WT F T+VN SSSE FLIG NYLG K +DG MHANYIFWR
Sbjct 6558 SWNKDLYELIQRFEYWTVFCTSVNTSSSEGFLIGINYLGPYCDKAIVDGNIMHANYIFWR 6617
Query 7008 NTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSS 7067
N+ + LS S+ D KF + +++LKE ++N+M+ LL KG+L+IR N +++
Sbjct 6618 NSTIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVIGLLRKGKLLIRNNGKLLNFG 6677
Query 7068 DILVNN 7073
+ VN
Sbjct 6678 NHFVNT 6683
Score = 206 bits (524), Expect = 8e-51, Method: Composition-based stats.
Identities = 73/367 (20%), Positives = 117/367 (32%), Gaps = 32/367 (9%)
Query 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQF-GPTYLDGADVTKIKPHVN 1589
D+ + + +I V T DN N V TYG+Q G + DVT P
Sbjct 1475 DQERQTIENFFSCSIPVNVTEDNVNHERVSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAF 1534
Query 1590 HEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADN 1649
G+ D F S Y K++ K DN
Sbjct 1535 DVGQKVIKAIDIDWQAHYGFRDAAAFSASSHDAY--------KFEVVTHSNFIVHKQTDN 1586
Query 1650 NCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETM 1709
NC+++++ LALQ+L+ ++ P ++ + F ++ S GE GD +
Sbjct 1587 NCWINAICLALQRLKPQWKFPGVRGLWNEFLERKTQGFVHMLYHISGVKKGEPGDAELML 1646
Query 1710 THLLQHANLESAKRVLN-VVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGR 1768
L + + V + C C K G + G CV G
Sbjct 1647 HKLGDLMDNDCEIIVTHTTACDKCA-KVEKFVGPVVAAPLAIH-------GTDETCVHGV 1698
Query 1769 DATQYLVQQESSFVMMS--APPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETL---- 1822
+ Q + + + S P L+ ++C Y+G+ + GHYT+ + L
Sbjct 1699 SVNVKVTQIKGTVAITSLIGPIIGEVLEATGYIC---YSGSNRNGHYTYYDNRNGLVVDA 1755
Query 1823 ---YRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKK 1879
Y + L + V K + K+ E KL
Sbjct 1756 EKAYHFNRDLLQVTTAIASNF--VVKKPQAEERPKNCAFNKVAASPKIVQEQKLLAIESG 1813
Query 1880 DNAYYTE 1886
N TE
Sbjct 1814 ANYALTE 1820
Score = 193 bits (491), Expect = 5e-47, Method: Composition-based stats.
Identities = 88/397 (22%), Positives = 140/397 (35%), Gaps = 53/397 (13%)
Query 875 VVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEENF--------SSRMYCSFY 926
+V E V L P+ + N G+ D V T G F +
Sbjct 1171 IVLERAVFKLTPLKESF-NYGVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVK 1229
Query 927 PPDEEEEDDAECEEEEIDETCEHEYGTED----------------DYQGLPLEFGASAET 970
P + + EH Y + + +
Sbjct 1230 PVMHAVYTGTTQNGHYMVDDIEHGYCVDGMGIKPLKKRCYTSTLFINANVMTRAEKPKQE 1289
Query 971 VRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQF--TGYLKLTDNVAIKCVDIVKEAQ 1028
+VE+ E++ +++ E E P ++ + F G L ++ ++
Sbjct 1290 FKVEKVEQQPIVEENKSSIEKEEIQSPKNDDLILPFYKAGKLSFYQGALDVLINFLE--- 1346
Query 1029 SANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL 1088
P VIVNAAN LKH GGVA A++ T G + + S DY+K N + G +
Sbjct 1347 ---PDVIVNAANGDLKHMGGVARAIDVFTGGKLTERSKDYLKKNKSIAPGNAVFFENVIE 1403
Query 1089 AKKCLHVVGPNLNAGEDIQLLKAAYENF-NSQDILLAPLLSAGIFGAKPLQSLQVCVQTV 1147
L+ VGP L Y+ + +L PL+S GIF + SLQ ++TV
Sbjct 1404 HLSVLNAVGPRNGDSRVEAKLCNVYKAIAKCEGKILTPLISVGIFNVRLETSLQCLLKTV 1463
Query 1148 RTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPP--NTEDSKTEEKSVVQKPVDVK 1205
ND+ L V Y D + +E P TED+ E+ V
Sbjct 1464 --------NDRGLN---VFVYTDQERQTIENFFSCSIPVNVTEDNVNHERVSVSFDKTYG 1512
Query 1206 PKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHD 1242
++K T + + K +TN+L D+ K+
Sbjct 1513 EQLKG------TVVIKDKDVTNQLPSAFDVGQKVIKA 1543
Score = 103 bits (256), Expect = 1e-19, Method: Composition-based stats.
Identities = 57/271 (21%), Positives = 93/271 (34%), Gaps = 24/271 (9%)
Query 1587 HVNHEGKTFFVLPSDDTLR-SEAFEYYHTLDESF----LGRYMSALNHTKKWKFPQVGGL 1641
E +T V T + E D + +K + G
Sbjct 1024 SSQEEVETVEVADITSTEEDVDIVEVSAKDDPWAAAVDVQEAEQFNPSLPPFKTTNLNGK 1083
Query 1642 TSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGE 1701
+K DNNC++++ LQ + FN EA+ + + GD +F L A + G
Sbjct 1084 IILKQGDNNCWINACCYQLQAFDF-FN----NEAWEKFKKGDVMDFVNLCYAATTLARGH 1138
Query 1702 LGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVS 1761
GD + +L + +AK VL C CG+K +E ++ T ++ GV
Sbjct 1139 SGDAEYLLELMLN--DYSTAKIVLAAKCG-CGEKEIV---LERAVFKLTPLKESFNYGVC 1192
Query 1762 IPCVCGRDATQYLVQQESSFV---MMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITA 1818
C+ V+ FV + P + + YTG Q GHY
Sbjct 1193 GDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHA--VYTGTTQNGHYMVDDI 1250
Query 1819 KETLYRIDGAHLTKMSEYKGPVTDVFYKETS 1849
+ Y +DG + K T + +
Sbjct 1251 EHG-YCVDGMGIKP--LKKRCYTSTLFINAN 1278
Score = 69.7 bits (169), Expect = 1e-09, Method: Composition-based stats.
Identities = 74/378 (20%), Positives = 119/378 (31%), Gaps = 56/378 (15%)
Query 185 YVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTER 244
YVD CG DG P+ + DY + E+ AW T R
Sbjct 113 YVDQYMCGADGKPV---------------IEGDFKDYFG-DEDIIEFEGEEYHCAWTTVR 156
Query 245 SDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVY 304
+K QT F I+ + + P N + + P V+K + +Y
Sbjct 157 DEKPLNQQTLFTIQEIQYNLDIPHKLP------NCATRHVAPPVKKNSKIVLSEDYKKLY 210
Query 305 PVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATC-EHCGTENLVIEGPTTCGYLPTN 363
+ S M C + T F+ AT CG+E+ + T
Sbjct 211 DIFG---------SPFMGNGDCLSKCFDTLHFIAATLRCPCGSESSGVGDWTG------- 254
Query 364 AVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYW 423
K C G ++ D + T + G + F CV Y G + W
Sbjct 255 --FKTACCGLSGKVKGV--TLGDIKPGDAVVTSMSAGKGVKFFANCVLQYAGDVEGVSIW 310
Query 424 -VPRASADIGSGHT-GITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFS 481
V + + T G G+ + + + +++ I GD II
Sbjct 311 KVIKTFTVDETVCTPGFEGELNDFIKPESKSLVACSVKRAFITGDIDDAVHDCIITGKLD 370
Query 482 ASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAA 541
ST+ F + L +K V+ CG V AW + ++ + L Q
Sbjct 371 LSTNLFGNV--GLLFKKTPWFVQKCGALFV-------DAWKVVEE--LCGSLTLTYKQIY 419
Query 542 GVIRSIFARTLDAANHSI 559
V+ S+ N+
Sbjct 420 EVVASLCTSAFTIVNYKP 437
Score = 52.8 bits (125), Expect = 2e-04, Method: Composition-based stats.
Identities = 126/755 (17%), Positives = 216/755 (29%), Gaps = 113/755 (15%)
Query 659 IVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNL-GEVFIAQSKGLY 717
++ ++V D K NK + + I G + FI + +Y
Sbjct 737 LIGNGVKVVCDGCKGFANQLSKGYNKLCNAARNDIEIGGIPFSTFKTPTNTFIEMTDAIY 796
Query 718 RQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGA 777
+GK L D + + E + +
Sbjct 797 SVIEQGKA----------------LSFRDADVPVVDNGTISTADWSEPILLEPAEYVKPK 840
Query 778 IVGTPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDT-VWEVQG 836
G + + G + +D+ Y G K G K V+F E+ V E+
Sbjct 841 NNGNVIVIAGYTFYKDEDEHFYPY---GFGKIVQRMYNKMGGGDKTVSFSEEVDVQEIAP 897
Query 837 YKNVRITFELD-ERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMG 895
V++ FE D E V VL +GT E++ + L + D L N G
Sbjct 898 VTRVKLEFEFDNEIVTGVLERAIGTRYKFTGTT----WEEFEESISEELDAIFDTLANQG 953
Query 896 IDLDE-WSVATFYLFD-DAGEENFSSRMYCSFYPP-------------DEEEEDDAECEE 940
++L+ + T FD + S+ + E E+D E E
Sbjct 954 VELEGYFIYDTCGGFDIKNPDGIMISQYDINITADEKSEVSASSEEEEVESVEEDPENEI 1013
Query 941 EEIDETCEHEYGTEDDYQGLPLEFGASAETV-RVEEEEEEDWLDDTTEQSEIEPEPEPTP 999
E E E E+ + ++ E V VE ++D + E E P
Sbjct 1014 VEASEGAEGTSSQEEVETVEVADITSTEEDVDIVEVSAKDDPWAAAVDVQEAEQFNPSLP 1073
Query 1000 EEPVNQFTGYLKLT--DNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKAT 1057
G + L DN + N A K G +
Sbjct 1074 PFKTTNLNGKIILKQGDNNCWINACCYQLQA---FDFFNNEAWEKFKKGDVMDFVNLCYA 1130
Query 1058 NGAMQK------------ESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNA--- 1102
+ + +DY L C L + + P +
Sbjct 1131 ATTLARGHSGDAEYLLELMLNDYSTAKIVLAAKCGCGEKEIVLERAVFKLT-PLKESFNY 1189
Query 1103 ---GEDIQLLKAAYENFNSQDILLAPLLSA----GIFGAKPLQSLQVCVQT------VRT 1149
G+ +Q+ + + + + +LS +F KP+ T V
Sbjct 1190 GVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHAVYTGTTQNGHYMVDD 1249
Query 1150 QVYIAVND----KALYEQVVMDYL---DNLKPRVEAPKQE--------EPPNTEDSKTEE 1194
+ D K L ++ L N+ R E PKQE +P E+ + E
Sbjct 1250 IEHGYCVDGMGIKPLKKRCYTSTLFINANVMTRAEKPKQEFKVEKVEQQPIVEENKSSIE 1309
Query 1195 KSVVQKPVDVKPKI-----------KACIDEVTTTLEETKFL---TNKLLLFADINGKLY 1240
K +Q P + + + +D + LE + L + +
Sbjct 1310 KEEIQSPKNDDLILPFYKAGKLSFYQGALDVLINFLEPDVIVNAANGDLKHMGGVARAID 1369
Query 1241 HDSQNMLRGEDMSFLEKDAPYMVG------DVITSGDITCVVIPSKKAGGTTEMLSRALK 1294
+ L +L+K+ G +VI + V P L K
Sbjct 1370 VFTGGKLTERSKDYLKKNKSIAPGNAVFFENVIEHLSVLNAVGPRNGDSRVEAKLCNVYK 1429
Query 1295 KVPV--DEYITTYPGQGCAGYTLEEAKTALKKCKS 1327
+ + +T G LE + L K +
Sbjct 1430 AIAKCEGKILTPLISVGIFNVRLETSLQCLLKTVN 1464
>sp|Q98VG9|R1AB_FIPV Replicase polyprotein 1ab OS=Feline coronavirus
(strain FIPV WSU-79/1146) OX=33734 GN=rep PE=1 SV=2
Length=6709
Score = 6696 bits (17373), Expect = 0.0, Method: Composition-based stats.
Identities = 2219/4982 (45%), Positives = 3033/4982 (61%), Gaps = 177/4982 (4%)
Query 2145 YMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLC--LDAGINYVKSPKFSK 2202
Y F ++ F + K K V++ + +
Sbjct 1849 YADVFFMAGDKILRFLLEVFKYLLVVFMCLRKSKMPKVKVKPPHVFRNLGAKVRTLNYVR 1908
Query 2203 LFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGS 2262
+ + L + + + C+G + Y NSS + C S
Sbjct 1909 QLNKPALWRYIKLVLLLIALYHFFYLFVSIPVVHKLACSGSVQAYSNSS-FVKSEVCGNS 1967
Query 2263 FPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSA 2322
C CL+ D L + L+ YK D + L+Y +F F +
Sbjct 1968 ILCKACLASYDELADFDHLQVSW----DYKSDPLWNRVIQ---LSYFIFLAVFG----NN 2016
Query 2323 IMQVFFGYFASHFISNSWLMWF-------IISIVQMAPVSAMVRMYIFFASFYYIWKSYV 2375
++ YF S ++ N WL +F + +V +S + + K
Sbjct 2017 YVRCLLMYFVSQYL-NLWLSYFGYVKYSWFLHVVNFESISVEFVIIVVVFKAVLALK--- 2072
Query 2376 HIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTF 2435
HI C + +C C K R TR+ +VNG ++ YV+ANG CK HN+ C NCD++
Sbjct 2073 HIFLPCNNPSCKTCSKIARQTRIPIQVVVNGSMKTVYVHANGTGKLCKKHNFYCKNCDSY 2132
Query 2436 CTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLY---------FDKAG 2486
TFI DE+ RDLS K+ + TD+S V V +G Y +D
Sbjct 2133 GFDHTFICDEIVRDLSNSIKQTVYATDRSYQEVTKVECTDGFYRFYVGEEFTAYDYDVKH 2192
Query 2487 QKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPI 2546
+K + L LD+ N GS ++ ++ VY+SQL+ +PI
Sbjct 2193 KKYSSQEVLKTMFLLDDFIVYNPSGSSL--------------ASVRNVCVYFSQLIGRPI 2238
Query 2547 LLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGV 2606
+++ L+ D+ S + +F+A + +F+V + + K L E K LD
Sbjct 2239 KIVNSELLEDL--SVDFKGALFNAKKNVIKNSFNVDVSECKNL-----EECYKLCNLDVT 2291
Query 2607 LSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKV--ENMTPRD 2664
STF A +H + +T S NNF + K ++ D
Sbjct 2292 FSTFEMAINN------------------AHRFGILITDRSFNNFWPSKIKPGSSGVSAMD 2333
Query 2665 LGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATT 2724
+G C+ +A+ +NA+V S++W +D+ +LS +K + + + F LT
Sbjct 2334 IGKCMTFDAKIVNAKVLTQRGKSVVWLSQDFSTLSSTAQKVLVKTFVEEGVNFSLTFNAV 2393
Query 2725 RQVVNVI----TTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYT 2780
++ T +S K G K + + C++ + Y + V++++
Sbjct 2394 GSDEDLPYERFTESVSAKSGSGFFDVLKQLKQ-LFWCLVLFITLYGLCSVYSVATQSYID 2452
Query 2781 N-EIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKN-DKSCPVVAA-IITR 2837
+ E Y I++GV + + +C N + GF WF + G DKSCP+V +
Sbjct 2453 SAEGYDYMVIKNGVVQSFDDSINCVHNTYKGFAVWFKAKHGFVPTFDKSCPIVLGTVFDL 2512
Query 2838 EIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECT 2897
+P +P V A+ G L F V N+CY + + CV + CT
Sbjct 2513 GNMRPIPDVPAYV--ALVGRSLVFAINAAFGVTNVCYDHTGAAVSKNSYFDTCVFNSACT 2570
Query 2898 IFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD 2957
G V YC L+EG+ YSEL PD Y G++++ P +R V T
Sbjct 2571 TLTGIGGT-VVYCAKQGLVEGAKLYSELLPDYYYEHASGNMVKIPAIIRSFGLRFVKTQA 2629
Query 2958 AEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGA 3017
YCR G C S+ G C +V + E G CG + N+F +
Sbjct 2630 TTYCRVGECTESQAGFCFGGDNWFVYDKEF---GDGYICGSSTLGFFKNVFALFNSNMSV 2686
Query 3018 LDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSF 3077
+ S +++A +IA L Y +KF+++FG+ +V ++ L+ + V +F
Sbjct 2687 VATSGAMLANIVIACLAIAVCYGVLKFKKIFGDCTLLVVM-IIVTLVVNNVSYFVTQNTF 2745
Query 3078 LPGVYSVFYLYLTFYFTNDVSFLAHLQ--WFAMFSPIVPFWITAIYVFCISLKHCHWFFN 3135
VY++ Y ++ T +++ L + + + P+++ +Y+ F
Sbjct 2746 FMIVYAIIY----YFTTRKLAYPGVLDAGFIIAYLNMAPWYVLVLYIMVFLYDSLPSLFK 2801
Query 3136 NYLRKRVMFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYF 3194
+ +F G F +FE AA+ TF+++ Y L + T L + Y +NKYKY+
Sbjct 2802 LKVTTN-LFEGDKFVGSFESAAMGTFVIDMRSYETLVNST--SLDRIKSYANSFNKYKYY 2858
Query 3195 SGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVE 3254
+G++ YR A HL KAL D+S S D+LY PP S+ S LQSG RKMA PSG VE
Sbjct 2859 TGSMGEADYRMACYAHLGKALMDYSVSRNDMLYTPPTVSVNST-LQSGLRKMAQPSGVVE 2917
Query 3255 GCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQ 3314
C+V+V G LNGLWL D V CPRHVI + + NYE+ L H+F + N
Sbjct 2918 PCIVRVAYGNNVLNGLWLGDEVICPRHVIASDTSRV-INYENELSSVRLHNFSIAKNNAF 2976
Query 3315 LRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNH 3374
L V+ + L LKV+ NP TP++KF ++PG++F++LACY G P VY MR
Sbjct 2977 LGVVSAKYKGVNLVLKVNQVNPNTPEHKFKSVRPGESFNILACYEGCPGSVYGVNMRSQG 3036
Query 3375 TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAA 3434
TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++LEG+ YG + D+ + Q
Sbjct 3037 TIKGSFIAGTCGSVGYVLENGTLYFVYMHHLELGNGSHVGSNLEGEMYGGYEDQPSMQLE 3096
Query 3435 GTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLS 3494
GT+ + NV+A+LYAA+ING+RWF+ + TL +N A ++ + D L+
Sbjct 3097 GTNVMSSDNVVAFLYAALINGERWFVTNTSMTLESYNAWAKTNSFTEIVS--TDAFNMLA 3154
Query 3495 AQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ-GKFKKIV 3553
A+TG +V + + L G GRTIL L DEFTP +V+RQ GV Q GK K I
Sbjct 3155 AKTGYSVEKLLECIVRL-NKGFGGRTILSYGSLCDEFTPTEVIRQMYGVNLQSGKVKSIF 3213
Query 3554 KGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLL-VKHKHAF 3612
+ + F L + ++ F ++ F+ L I + + ++ +KHK F
Sbjct 3214 YPMMTAIAILFAFWL----EFFMYTPFTWINP-TFVSVVLAITTLVSVLLVAGIKHKMLF 3268
Query 3613 LCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILM 3672
F++PS+ N V ++ + +E +T+ ++ ++ +V+ ++
Sbjct 3269 FMSFVMPSVILATAHN-VVWDMTYYESLQVLVENVNTTFLPVDMQGVMLALFCVVVFVIC 3327
Query 3673 TART------VYDDAARRVWTLMNVITLVYKVYYGNALD----QAISMWALVISVTSNYS 3722
T R + A ++ + N++ L+ + D ++M ++IS+T+
Sbjct 3328 TIRFFTCKQSWFSLFATTIFVMFNIVKLLGMIGEPWTDDHFLLCLVNMLTMLISLTTKDW 3387
Query 3723 GVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFR 3782
VV +A IV ++ P ++C+ ++Y GY CCY+G+ +NR+
Sbjct 3388 FVVFASYKVAYYIVVYVMQ--PAFVQDFGFVKCVSIIYMACGYLFCCYYGILYWVNRFTC 3445
Query 3783 LTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDV 3842
+T GVY + VS E +YM + L PK++ DA L+ KL+GIGG IK++TVQSK++++
Sbjct 3446 MTCGVYQFTVSPAELKYMTANNLSAPKTAYDAMILSFKLMGIGGGRNIKISTVQSKLTEM 3505
Query 3843 KCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAV 3902
KCT+VVLL +L ++ VES+SK W CV LHN+I L D EK+++L++ LS
Sbjct 3506 KCTNVVLLGLLSKMHVESNSKEWNYCVGLHNEINLCDDPDAVLEKLLALIAFFLSKHNTC 3565
Query 3903 DINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLN 3962
D++ L E +N LQ++AS +++LPS+ AY A+ E+A N S +LK+L K+ N
Sbjct 3566 DLSDLIESYFENTTILQSVASAYAALPSWIAYEKARADLEEAKKNDVSPQLLKQLTKACN 3625
Query 3963 VAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDAL 4022
+AKSEF+R+A++Q+KL+KMA+QA MYK+AR+ D+++K+ SAM ++LF ML+KLD ++
Sbjct 3626 IAKSEFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDMSSV 3685
Query 4023 NNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDAD 4082
N II AR+G +PL+IIP +A +L+VV P+ N YA A+W I +V DA+
Sbjct 3686 NTIIEQARNGVLPLSIIPAASATRLIVVTPNLEVLSKVRQENNVHYAGAIWSIVEVKDAN 3745
Query 4083 SKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTD 4142
V L E+ N N+ WPL +T R KLQNNE+ P L++ + A T
Sbjct 3746 GAQVHLKEVTAANELNITWPLSITCERT---TKLQNNEILPGKLKEKAVKASATIDGDAY 3802
Query 4143 DNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKV 4202
+ A + G F+ A ++ +LK+ ++ + I ELE P RF D GP+V
Sbjct 3803 GSGKALMASEGGKSFIYAFIASDSNLKYVKWESN--NDVIPIELEAPLRFYVDGVNGPEV 3860
Query 4203 KYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLA 4262
KYLYF+K LN L RG VLG + ATVRLQAG TE P+NS +L+ CAFA DPAKAY D +
Sbjct 3861 KYLYFVKSLNTLRRGAVLGYIGATVRLQAGKPTEHPSNSGLLTLCAFAPDPAKAYVDAVK 3920
Query 4263 SGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDL 4322
G QP+TNCVKML G G AIT E+N Q+S+GGAS C+YCRCH++HP G C
Sbjct 3921 RGMQPVTNCVKMLSNGAGNGMAITNGVESNTQQDSYGGASVCIYCRCHVEHPAIDGLCRF 3980
Query 4323 KGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCG 4382
KGK+VQ+PT DP+ F + N VC VCG W GC CD R + + ++LN
Sbjct 3981 KGKFVQVPTG-TQDPIRFCIENEVCVVCGCWLTNGCMCD--RTSIQGTTIDQSYLNECGV 4037
Query 4383 VSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVK 4442
+ L PC GT D V RAFDIYN+ VA KFLKTNC RF+ D+ D+Y+VVK
Sbjct 4038 LVQLDLEPC-NGTDPDHVSRAFDIYNKDVACIGKFLKTNCSRFRNLDKH----DAYYVVK 4092
Query 4443 RHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRH 4502
R T S HE+ YN +KD VA HDFF ++ +++R+ LTKYTM DL YA+R+
Sbjct 4093 RCTKSVMDHEQVCYNDLKDSGVVAEHDFFLYKEGRCEFGNVARKDLTKYTMMDLCYAIRN 4152
Query 4503 FDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFC 4562
FDE NC+ LKEILVT C++ +F KDW+D VEN I VYA LG V ++LK V FC
Sbjct 4153 FDEKNCEVLKEILVTLGACNESFFENKDWFDPVENEAIHEVYARLGPIVANAMLKCVAFC 4212
Query 4563 DAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAA 4622
DA+ + G +G++TLDNQDLNGN+YDFGDFV+ PG G V SYYS +MP++ +T L +
Sbjct 4213 DAIVEKGYIGIITLDNQDLNGNFYDFGDFVKTTPGFGCACVTSYYSYMMPLMGMTSCLES 4272
Query 4623 ESHMDADL-AKPLIKWDLLKYDFTEERLCLFDRYFKYWDQTYHPNCINCLDDRCILHCAN 4681
E+ + +D+ ++DLL YDFT+ + LF +YFK+WD+TYHPNC +C D CI+HCAN
Sbjct 4273 ENFVKSDIYGADYKQYDLLAYDFTDHKEKLFHKYFKHWDRTYHPNCSDCTSDECIIHCAN 4332
Query 4682 FNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELL 4741
FN LFS P T+FGPLVRK+ +DGVP VV+ GYHF++LG+V N DV L + +LS +LL
Sbjct 4333 FNTLFSMTIPSTAFGPLVRKVHIDGVPVVVTAGYHFKQLGIVWNLDVKLDTMKLSMTDLL 4392
Query 4742 VYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEG 4801
+ DP + AS LLD+RT CFS+AAL+ V +QTVKPG+FNKDFYDF +GFF+EG
Sbjct 4393 RFVTDPTLLVASSPALLDQRTVCFSIAALSTGVTYQTVKPGHFNKDFYDFITERGFFEEG 4452
Query 4802 SSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQ 4861
S + LKHFFFAQ G AA++D++YYRYN T+ DI Q FV ++V KYF+CYDGGCINA +
Sbjct 4453 SELTLKHFFFAQGGEAAMTDFNYYRYNRVTVLDICQAQFVYKIVGKYFECYDGGCINARE 4512
Query 4862 VIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKN 4921
V+V N DKSAG+P NK+GKARLYY+++SYE+QDALFA TKRNV+PT+TQMNLKYAIS K
Sbjct 4513 VVVTNYDKSAGYPLNKFGKARLYYETLSYEEQDALFALTKRNVLPTMTQMNLKYAISGKA 4572
Query 4922 RARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETP 4981
RARTV GVS+ STMT RQ+HQK LKSIAATR ATVVIG++KFYGGW NMLK + DV+
Sbjct 4573 RARTVGGVSLLSTMTTRQYHQKHLKSIAATRNATVVIGSTKFYGGWDNMLKNLMRDVDNG 4632
Query 4982 HLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGS 5041
LMGWDYPKCDRA+PNM+R+ ++++L KH CC S RFYRL+NE AQVL+E+V C G
Sbjct 4633 CLMGWDYPKCDRALPNMIRMASAMILGSKHVGCCTHSDRFYRLSNELAQVLTEVVHCTGG 4692
Query 5042 LYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLY 5101
Y KPGGT+SGD TTAYANS FNI QAV+ANVN LL D N + V+++Q ++Y+ Y
Sbjct 4693 FYFKPGGTTSGDGTTAYANSAFNIFQAVSANVNKLLGVDSNACNNVTVKSIQRKIYDNCY 4752
Query 5102 RNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNV 5161
R+ +D EFV E+++YLRKHFSMMILSDD VVCYN +YA G VA I FKA LYYQNNV
Sbjct 4753 RSSSIDEEFVVEYFSYLRKHFSMMILSDDGVVCYNKDYADLGYVADINAFKATLYYQNNV 4812
Query 5162 FMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDG 5221
FMS +KCW E DL+ GPHEFCSQHT+ + D YLPYPDPSRIL AG FVDDIVKTD
Sbjct 4813 FMSTSKCWVEPDLSVGPHEFCSQHTLQIVGPDGDYYLPYPDPSRILSAGVFVDDIVKTDN 4872
Query 5222 TLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNT 5281
+M+ER+VSLAIDAYPLTKHP Y VF+ L +++ L L +LD +SV + +
Sbjct 4873 VIMLERYVSLAIDAYPLTKHPKPAYQKVFYTLLDWVKHLQKNLNAGVLDSFSVTMLEEGQ 4932
Query 5282 SRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHK 5341
++W EFY ++Y TVLQA G CV+C SQT LRCG C+RRP LC KC YDHV+ T HK
Sbjct 4933 DKFWSEEFYASLYEKSTVLQAAGMCVVCGSQTVLRCGDCLRRPLLCTKCAYDHVMGTKHK 4992
Query 5342 LVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGS 5401
++S+ PYVC+ GC+V DVT+L+LGG+SYYC HKP +SFPLCANG VFGLYK++ VGS
Sbjct 4993 FIMSITPYVCSFNGCNVNDVTKLFLGGLSYYCMDHKPQLSFPLCANGNVFGLYKSSAVGS 5052
Query 5402 DNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSD 5461
++V DFN +A DWTN DY LAN E LK+FAAET+KA EE+ K Y A ++EV+
Sbjct 5053 EDVEDFNKLAVSDWTNVEDYKLANNVKESLKIFAAETVKAKEESVKSEYAYAILKEVIGP 5112
Query 5462 RELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYG-DAVVYRGTTTYKL 5520
+E+ L WE K +PPLNRN VFT ++++K++K+Q+GE+ FE+ +YG D+V Y+ T+TYKL
Sbjct 5113 KEIVLQWEASKTKPPLNRNSVFTCFQISKDTKIQLGEFVFEQSEYGSDSVYYKSTSTYKL 5172
Query 5521 NVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYST 5580
G FVLTSH V PL A LV QE Y I+ LYP NI++ +++ V YQ +G QK++T
Sbjct 5173 TPGMIFVLTSHNVSPLKATILVNQEKYNTISKLYPVFNIAEAYNTLVPYYQMIGKQKFTT 5232
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+QGPPG+GKSH IGL LYYP ARIVYTACSHAAVDALCEKA K +D+CSRIIP R R
Sbjct 5233 IQGPPGSGKSHCVIGLGLYYPQARIVYTACSHAAVDALCEKAAKNFNVDRCSRIIPQRIR 5292
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
V+C+ FK N+T QY+FCTVNALPE + DIVV DE+SM TNYDLSV+N+RL KH VY+
Sbjct 5293 VDCYTGFKPNNTNAQYLFCTVNALPEASCDIVVVDEVSMCTNYDLSVINSRLSYKHIVYV 5352
Query 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
GDP QLPAPRTL+ KG L+P+ +N V + + T+GPD+FL C RCPAEIV TVSALVY+N
Sbjct 5353 GDPQQLPAPRTLINKGVLQPQDYNVVTQRVCTLGPDVFLHKCYRCPAEIVKTVSALVYEN 5412
Query 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
K +S QCFKMF KG + + +S+IN Q+ VV+ FL NP WRKAVFISPYNSQN
Sbjct 5413 KFVPVNPESKQCFKMFVKGQVQIESNSSINNKQLEVVKAFLAHNPKWRKAVFISPYNSQN 5472
Query 5821 AVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDR 5880
VA ++LGL TQTVDS+QGSEYDYVI+TQT++T H+ NVNRFNVAITRAK+GILCIM DR
Sbjct 5473 YVARRLLGLQTQTVDSAQGSEYDYVIYTQTSDTQHATNVNRFNVAITRAKVGILCIMCDR 5532
Query 5881 DLYDKLQFTSLEIPRRNVATLQAEN-VTGLFKDCSKIITGLHPTQAPTHLSVDIKFKT-E 5938
+Y+ L F L+ + LQA+ GLFKDCSK + P A T++S+ FKT +
Sbjct 5533 TMYENLDFYELKDSKI---GLQAKPETCGLFKDCSKSEQYIPPAYATTYMSLSDNFKTSD 5589
Query 5939 GLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHA 5998
GL V+I KD+ Y +IS MGF+ + GY +F TR+ A+R+VRAW+GFDVEG H
Sbjct 5590 GLAVNIG--TKDVKYANVISYMGFRFEANIPGYHTLFCTRDFAMRNVRAWLGFDVEGAHV 5647
Query 5999 TRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKG 6058
D VGTN+PLQLGFS GV+ V G V TE V A+ PPG+QF HLIPLM KG
Sbjct 5648 CGDNVGTNVPLQLGFSNGVDFVVQTEGCVVTEKGNSIEVVKARAPPGEQFAHLIPLMRKG 5707
Query 6059 LPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATC 6118
PW++VR +IVQM+ D GLSD ++FVLWA G ELT+M+YFVKIG + C C K ATC
Sbjct 5708 QPWHIVRRRIVQMVCDYFDGLSDILIFVLWAGGLELTTMRYFVKIGRPQKCE-CGKSATC 5766
Query 6119 FSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIM 6178
+S+S YAC+ H++G DY+YNP+ ID+QQWG+TG+L NH + C +H N HVAS DAIM
Sbjct 5767 YSSSQCVYACFKHALGCDYLYNPYCIDIQQWGYTGSLSMNHHEVCNIHRNEHVASGDAIM 5826
Query 6179 TRCLAVHECFVKRVDWSVEYPIIGDELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPK 6238
TRCLA+H+CFVKRVDWS+ YP I +E ++N A R VQ V+K+AL +HD+GNPK
Sbjct 5827 TRCLAIHDCFVKRVDWSIVYPFIDNEEKINKAGRIVQSHVMKAALKIFNPAAIHDVGNPK 5886
Query 6239 AIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANA 6298
I+C + W YD P ++ +E Y Y H +G+ LFWNCNVD YP +
Sbjct 5887 GIRCA-TTPIPWFCYDRDPINNNVRCLE---YDYMVHGQ--MNGLMLFWNCNVDMYPEFS 5940
Query 6299 IVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHG 6358
IVCRFDTR S L+L GC+GG+LYVN HAFHTPA+D+ AF LK +PFFYY DS CE
Sbjct 5941 IVCRFDTRTRSKLSLEGCNGGALYVNNHAFHTPAYDRRAFAKLKPMPFFYYDDSNCE--- 5997
Query 6359 KQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDT 6418
V +YVPLKS CIT+CN+GGAVC+ HA YR Y++ YNM + AGF++W + FDT
Sbjct 5998 -LVDGQPNYVPLKSNVCITKCNIGGAVCKKHAALYRAYVEDYNMFMQAGFTIWCPQNFDT 6056
Query 6419 YNLWNTFTR---LQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENK 6475
Y LW+ F LQSLENVA+NVV KG F G G+ P ++I + + + D IF NK
Sbjct 6057 YMLWHGFVNSKALQSLENVAFNVVKKGAFTGLKGDLPTAVIADKIMVRDGPTDKCIFTNK 6116
Query 6476 TTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTD 6535
T+LP NVAFEL+AKR + P + IL NLGV V+WDY+ E P T VC+ TD
Sbjct 6117 TSLPTNVAFELYAKRKLGLTPPLTILRNLGVVATYKFVLWDYEAECPFSNFTKQVCSYTD 6176
Query 6536 IAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVT 6595
+ S + FD + G + F ++ VLI+ +VKGL+ K +N +
Sbjct 6177 LD--------SEVVTCFDNSIAGSFERFTTTKDAVLISNNAVKGLSAIK-LQYGFLNDLP 6227
Query 6596 L--IGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQR 6653
+ +G T + Y +K ++Q+ ++Y+T R E FKPRS ME DFL + FIQ+
Sbjct 6228 VSTVGNKPVTWYIYVRKNGEYVEQI-DSYYTHGRTFETFKPRSTMEEDFLSMDTTLFIQK 6286
Query 6654 YKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFI-PMDSTVKNYFITDA 6712
Y LE Y FEH+V+GD S +GG+HL+I + ++ +++F+ DST+K+ IT A
Sbjct 6287 YGLEDYGFEHVVFGDVSKTTIGGMHLLISQVRLAKMGLFSVQEFMTNSDSTLKSCCITYA 6346
Query 6713 QTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYP 6772
SSK VC+ +D+LLDDFV IIKS DL+V+SKVV V +D +MLWC++ ++TFYP
Sbjct 6347 DDPSSKNVCTYMDILLDDFVTIIKSLDLNVVSKVVDVIVDCKAWRWMLWCENSQIKTFYP 6406
Query 6773 KLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTL 6832
+LQ+++ W PG +MP LYK+QRM LE+C+L NYG +P GI NV KYTQLCQYLNT
Sbjct 6407 QLQSAE-WNPGYSMPTLYKIQRMCLERCNLYNYGAQVRLPDGITTNVVKYTQLCQYLNTT 6465
Query 6833 TLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCAT 6892
T+ VP+ MRV+H GA GVAPG+ VLR+WLP +LVD+DL D+VSDAD ++ GDC +
Sbjct 6466 TVCVPHKMRVLHLGAAGASGVAPGSTVLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTS 6525
Query 6893 VHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWN 6952
++ +K+DL+ISD+YD TK + EN SK+GFFTY+ GFIK+KL+LGGS A+KITE SWN
Sbjct 6526 LYIEDKFDLLISDLYDGSTKSIDGENTSKDGFFTYINGFIKEKLSLGGSAAIKITEFSWN 6585
Query 6953 ADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGK--PKEQIDGYTMHANYIFWRNTN 7010
DLY+L+ F +WT F T+VN SSSE FLIG NYLG K +DG MHANYIFWRN+
Sbjct 6586 KDLYELIQRFEYWTVFCTSVNTSSSEGFLIGINYLGPYCDKAIVDGNIMHANYIFWRNST 6645
Query 7011 PIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDIL 7070
+ LS S+ D KF + +++LKE ++N+M+ LL KG+L+IR N +++ + L
Sbjct 6646 IMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVVGLLRKGKLLIRNNGKLLNFGNHL 6705
Query 7071 VN 7072
VN
Sbjct 6706 VN 6707
Score = 234 bits (597), Expect = 3e-59, Method: Composition-based stats.
Identities = 71/329 (22%), Positives = 115/329 (35%), Gaps = 24/329 (7%)
Query 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQF-GPTYLDGADVTKIKPHVN 1589
D+ + + TI + T D N V + TYG+Q G + DVT P V+
Sbjct 1486 DQERVTIENFFNGTIPIKVTEDTVNQKRVSVALDKTYGEQLKGTVVIKDKDVTNQLPSVS 1545
Query 1590 HEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADN 1649
G+ L + YY + + ++ K DN
Sbjct 1546 DVGEKVVK-----ALDVDWNAYYGFPNAAAFSASSH---DAYEFDVVTHNNFIVHKQTDN 1597
Query 1650 NCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETM 1709
NC+++++ LALQ+L+ + P ++ + A F ++ S T G+ GD T+
Sbjct 1598 NCWVNAICLALQRLKPTWKFPGVKSLWDAFLTRKTAGFVHMLYHISGLTKGQPGDAELTL 1657
Query 1710 THLLQHANLESAKRVLN-VVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGR 1768
L+ + +SA V + C C K T TG + L G CV G
Sbjct 1658 HKLVDLMSSDSAVTVTHTTACDKCA-KVETFTGPVVAAPL-------LVCGTDEICVHGV 1709
Query 1769 DATQYLVQQESSFVMMS--APPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRID 1826
+ + + S P + ++C YTG GHYT+ + L +D
Sbjct 1710 HVNVKVTSIRGTVAITSLIGPVVGDVIDATGYIC---YTGLNSRGHYTYYDNRNGL-MVD 1765
Query 1827 GAHLTKMSEYKGPVTDVFYKETSYTTTIK 1855
+ VT T K
Sbjct 1766 ADKAYHFEKNLLQVTTAIASNFVANTPKK 1794
Score = 160 bits (404), Expect = 7e-37, Method: Composition-based stats.
Identities = 74/336 (22%), Positives = 126/336 (38%), Gaps = 35/336 (10%)
Query 913 GEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL---PLEFGASAE 969
+ + M+ + + E+ I + C G + L A+
Sbjct 1248 SQFIVTPTMHAVYTGTTQS---GHYMIEDCIHDYCVDGMGIKPRKHKFYTSTLFLNANVM 1304
Query 970 TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQS 1029
T + + E + + + +P++ + F V+ D+
Sbjct 1305 TAKSKTMVEPPVPVEDKCVEDCQ-----SPKDLILPFYK----AGKVSFYQGDLDVLINF 1355
Query 1030 ANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA 1089
P V+VNAAN L+H GGVA A++ T G + K S +Y+K + + G + L
Sbjct 1356 LEPDVLVNAANGDLRHVGGVARAIDVFTGGKLTKRSKEYLKSSKAIAPGNAVLFENVLEH 1415
Query 1090 KKCLHVVGPNLNAGEDIQLLKAAYENFNSQD-ILLAPLLSAGIFGAKPLQSLQVCVQTVR 1148
L+ VGP L Y+ D +L PL+S GIF K SLQ ++TV
Sbjct 1416 LSVLNAVGPRNGDSRVEGKLCNVYKAIAKCDGKILTPLISVGIFKVKLEVSLQCLLKTV- 1474
Query 1149 TQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPP--NTEDSKTEEKSVVQKPVDVKP 1206
D+ L V Y D + +E P TED+ +++ V
Sbjct 1475 -------TDRDLN---VFVYTDQERVTIENFFNGTIPIKVTEDTVNQKRVSVALDKTYGE 1524
Query 1207 KIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHD 1242
++K T + + K +TN+L +D+ K+
Sbjct 1525 QLKG------TVVIKDKDVTNQLPSVSDVGEKVVKA 1554
Score = 95.5 bits (236), Expect = 2e-17, Method: Composition-based stats.
Identities = 66/358 (18%), Positives = 117/358 (33%), Gaps = 32/358 (9%)
Query 1551 VDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFE 1610
V + T V + +Q + + P + + D + ++
Sbjct 1025 VSSVEGETVSVVDVEDFVEQVSLVEENNVLTPAVNP-----DEQLSSVEKKDEVSAKNDP 1079
Query 1611 YYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAP 1670
+ +DE +K + G +K DNNC++++ LQ + FN
Sbjct 1080 WAAAVDEQ---EAEQPKPSLTPFKTTNLNGKIILKQQDNNCWINACCYQLQAFDF-FN-- 1133
Query 1671 ALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCK 1730
+ + + D F A G+ GD + +L + +AK L+ C
Sbjct 1134 --HDLWDGFKKDDVMPFVDFCYAALTLKQGDSGDAEYLLETMLN--DYSTAKVTLSAKCG 1189
Query 1731 HCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFV---MMSAP 1787
CG K +E ++ T + K GV C V+ FV +
Sbjct 1190 -CGVKEIV---LERTVFKLTPLRNEFKYGVCGDCKQINMCKFASVEGSGVFVHDRIEKQT 1245
Query 1788 PAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKE 1847
P + T YTG Q GHY Y +DG + ++K + +F
Sbjct 1246 PVSQFIVTPTMHA--VYTGTTQSGHYMIEDCIHD-YCVDGMGIKP-RKHKFYTSTLFLNA 1301
Query 1848 TSYTTTIK-----PVSYKLDGVTYTEIEPKLD-GYYKKDNAYYTEQPIDLVPTQPLPN 1899
T K PV + V + L +YK + + +D++ P+
Sbjct 1302 NVMTAKSKTMVEPPVPVEDKCVEDCQSPKDLILPFYKAGKVSFYQGDLDVLINFLEPD 1359
Score = 68.9 bits (167), Expect = 2e-09, Method: Composition-based stats.
Identities = 51/274 (19%), Positives = 99/274 (36%), Gaps = 12/274 (4%)
Query 746 SHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSPG 805
+ +T+ ++ + + + + G + + G + +D Y
Sbjct 809 TASVPVTNSGIITTDDWSDPILLEPADYVEPKDNGDVIVIAGYTFYKDEDDHFYP--YGS 866
Query 806 LLATNNVFRLKGGAPIKGVTFGED-TVWEVQGYKNVRITFELD-ERVDKVLNEKCSVYTV 863
+ ++ GG K V+F ++ V E++ VR+ FE D E V +VL +
Sbjct 867 GMVVQKMYNKMGGGD-KSVSFSDNVNVREIEPVTRVRLEFEFDNEVVTQVLEKVIGTKYK 925
Query 864 ESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE-WSVATFYLFDDAGEENFSSRMY 922
GT EF +++ + L + D L G++L+ + T FD + Y
Sbjct 926 FIGTTWEEF----EDSISEKLDKIFDTLAEQGVELEGYFIYDTCGGFDINNPDGVMISQY 981
Query 923 CSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWL 982
D++ + DA E+ + E E+D + +V E D
Sbjct 982 DLNTAADDKSDSDASVEDISLISDNEDVEQIEEDNTST--DDAEDVSSVEGETVSVVDVE 1039
Query 983 DDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNV 1016
D + S +E TP ++ ++ D V
Sbjct 1040 DFVEQVSLVEENNVLTPAVNPDEQLSSVEKKDEV 1073
Score = 58.5 bits (140), Expect = 4e-06, Method: Composition-based stats.
Identities = 81/420 (19%), Positives = 129/420 (31%), Gaps = 65/420 (15%)
Query 180 GAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIA 239
G YVD CG DG P+ E DY V E+ A
Sbjct 108 GNGAIYVDQYMCGADGKPV---------------IEGEFKDYFG-DEDVIIYEGEEYHCA 151
Query 240 WFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGR 299
W T R +K QT I+ + + P N ++ + P V+K
Sbjct 152 WLTVRDEKPLWQQTLLTIREIQYNLDIPHKLP------NCAIREVAPPVKKNSKVVLSEE 205
Query 300 IRSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKAT-CEHCGTENLVIEGPTTCG 358
R +Y + S M + + F+ AT CG E+ + T
Sbjct 206 YRKLYDIFG---------SPFMGNGDSLNTCFDSLHFIAATLKCPCGAESSGVGDWTG-- 254
Query 359 YLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYN 418
K C G ++ I T + G + F V Y G
Sbjct 255 -------FKTACCGLHGKVKGV--TLGAVKPGDAIVTSMSAGKGVKFFANSVLQYAGDVE 305
Query 419 KRAYW-VPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEE----- 472
+ W V + + T + E D + S V+ +I F E
Sbjct 306 NVSVWKVIKTFTVNETVCT----TDFEGELNDFIRPESTSPVSCSIKRAFITGEVDDAVH 361
Query 473 VAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTP 532
II ST+ F +L +K V+ CG AW + ++ +L
Sbjct 362 DCIIAGKLDLSTNLFGSA--NLLFKKMPWFVQKCGAI-------FADAWKVVEE--LLCS 410
Query 533 LCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLT 592
L Q V+ S+ ++ P ++ ++ D + + LV A + +T
Sbjct 411 LKLTYKQIYDVVASLCTSAFTIMDYK-PVFVVSSNSVKDLVDKCVKILVKAFDVFTQTIT 469
>sp|P0C6Y3|R1AB_IBVM Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=rep PE=1 SV=1
Length=6631
Score = 6409 bits (16628), Expect = 0.0, Method: Composition-based stats.
Identities = 2354/5670 (42%), Positives = 3267/5670 (58%), Gaps = 354/5670 (6%)
Query 1540 REVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLP 1599
K ++ T D + ++ + G QFG + V + E K +P
Sbjct 1175 ATCKQKTIYLTEDGVKYRSVVLKPGDSLG-QFGQVFARNKVVFSA---DDVEDKEILFIP 1230
Query 1600 SDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLA 1659
+ D E Y+ LD Y+ L +KW ++W D NC++SS ++
Sbjct 1231 TTDKTILE----YYGLDAQKYVTYLQTL--AQKWDVQYRDNFVILEWRDGNCWISSAIVL 1284
Query 1660 LQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE 1719
LQ +++F L EA+ + GD +F A A N VG+ D + +L +H + +
Sbjct 1285 LQAAKIRFKG-FLAEAWAKLLGGDPTDFVAWCYASCNAKVGDFSDANWLLANLAEHFDAD 1343
Query 1720 SAKRVL-NVVCKHCGQKTTTLTGVEAVM-YMGTLSYDNLKTGVSIPCVCGRDATQYLVQQ 1777
+L V +CG K+ L G+EA + + + + KT S CG +T +++
Sbjct 1344 YTNALLKKCVSCNCGVKSYELRGLEACIQPVRAPNLLHFKTQYSNCPTCGASSTDEVIEA 1403
Query 1778 ESSFVMMSAPPAEYKLQ-QGTFLCANEYTGNYQCGH-YTHITAKETLYRIDGAHLTKMSE 1835
++++ A + + + G+ GH YT K D +
Sbjct 1404 SLPYLLLFATDGPATVDCDENAVGTVVFIGSTNSGHCYTQADGKA----FDNLAKDRKFG 1459
Query 1836 YKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQ 1895
K P Y S + P L + K A ++ + + T
Sbjct 1460 RKSPYITAMYTRFSLRSE----------------NPLLVVEHSKGKAKVVKEDVSNLATS 1503
Query 1896 PLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSAS 1955
ASFD+ D Q + L V PD + Y +
Sbjct 1504 SK--ASFDDL----------TDFEQW--YDSNIYESLKVQETPD--------NLDEYVSF 1541
Query 1956 FKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDN 2015
T + + P T +R + S + + F DT
Sbjct 1542 ------------------TTKEDSKLPLTLKVRGIKSVVDFRSKDGFTYKLTPDTD---- 1579
Query 2016 LACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
S+ P V+++ +++ +E VVG+ + E +
Sbjct 1580 --ENSKTPVYYPVLDSISLRAIWVEGSAN--FVVGHPNYYSKSLRIPTFWENAESFVKMG 1635
Query 2076 Y-VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCA 2134
Y ++ ++ + + L+ + A ++ S ++ Q A
Sbjct 1636 YKIDGVTMGLWRAEHLNK----PNLERIFNIAKKAIVGSSVVT------TQCGKILVKAA 1685
Query 2135 KRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINY 2194
+A +V + + + + LC FT+ + + K V + +
Sbjct 1686 TYVADKVGDGVVRNITDRIKGLCGFTRGHFEK---KMSLQFLKTLVFFFFYFLKASSKSL 1742
Query 2195 VKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVT 2254
V S K + LL++ S V VL S C + +S +V
Sbjct 1743 VSSYKIVLCKVVFATLLIVWFIYTSNPVVFTGIRVL-DFLFEGSLCGPYNDYGKDSFDV- 1800
Query 2255 TMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKF 2314
+ +C G F C +CL DSL Y +++ YK + G+ W Y++F
Sbjct 1801 -LRYCAGDFTCRVCLHDRDSLHLYKHAYSVE---QIYKDAAS--GINFNWNWLYLVFLIL 1854
Query 2315 F-----YLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYY 2369
F + + ++ +L WF V + + F + +Y
Sbjct 1855 FVKPVAGFVIICYCVKYLVLSSTVLQTGVGFLDWF---------VKTVFTHFNFMGAGFY 1905
Query 2370 IWKSYV-----HIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKT 2424
W Y H + C TC +C + R+ R E + +V G K+ +VY N G FCK
Sbjct 1906 FWLFYKIYVQVHHILYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYTNSGYNFCKR 1965
Query 2425 HNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDK 2484
HNW C NCD + +TF+S EVA +LS + KR + PT + ++V V + ++L +
Sbjct 1966 HNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKPTAYAYHVVYEACVVDDFVNLKYKA 2025
Query 2485 A-GQKTYERHPLSHFVNLDNL-RANNTKGSLPINVIVFDGKSKCDESA------SKSASV 2536
A K + F D L +A K +L I DG C+ + +K+A+V
Sbjct 2026 AIPGKDNASSAVKCFSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSAHALEEAKNAAV 2085
Query 2537 YYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSE 2596
YY+Q +C+PIL+LDQAL + VS + D S SV TA
Sbjct 2086 YYAQYLCKPILILDQALYEQL-IVEPVSKSVIDKVCSILSNIISVD---------TAALN 2135
Query 2597 LAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYN- 2655
G D +LS ++ ++ H+ ++E TGD N + +Y
Sbjct 2136 YKAGTLRDALLSI-------------TKDEEAVDMAIFCHNHEVEYTGDGFTNVIPSYGM 2182
Query 2656 KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNI 2715
+ +TPRD G I+ +A N +V + ++W D + LS+ K + SA K+
Sbjct 2183 DTDKLTPRDRGFLINADASIANLRVKNAP--PVVWKFSDLIKLSDSCLKYLISATVKSGG 2240
Query 2716 PFRLTCATTRQVVNVITTKISL--KGGKIVSTCFKL------MLKATLLCVLAALVCYIV 2767
F +T + +QV++ T K+ + K G +++ FK L + A + Y
Sbjct 2241 RFFITKSGAKQVISCHTQKLLVEKKAGGVINNTFKWFMSCFKWLFVFYILFTACCLGYYY 2300
Query 2768 MPVHTLSIHDGY----TNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGSYK 2823
M ++ +H Y T + G+K I GV R+I+S D+CF+NK FDA++ G SY+
Sbjct 2301 MEMNKSFVHPMYDVNSTLHVEGFKVIDKGVIREIVSEDNCFSNKFVNFDAFW---GKSYE 2357
Query 2824 NDKSCPVVAAIITREIGFIVPGLPGTVLRAING-DFLH---------FLPRVFSAVGNIC 2873
N+K+CP+V +I + G + G+PG V ++G F+H ++P F+ +
Sbjct 2358 NNKNCPIVTVVIDGD-GTVAVGVPGFVSWVMDGVMFVHMTQTDRRPWYIPTWFNRE-IVG 2415
Query 2874 YTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD-TNLLEGSISYSELRPDTRYV 2932
YT +I F TS + +A C ++ A P YC++ N G++ + + P Y
Sbjct 2416 YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALPFGSIIPHRVYF 2474
Query 2933 LMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALS 2992
+G + P L + +V YCR CE ++ G C+S +WVL N+ Y +
Sbjct 2475 QPNGVRLIVPQQILH-TPYIVKFVSDSYCRGSVCEYTKPGYCVSLDSQWVLFNDEYISKP 2533
Query 2993 GVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYN 3052
GVFCG L+ N+ + V ++ + +I +++ +KF+ VF Y
Sbjct 2534 GVFCGSTVRELMFNMVSTFFTGVNP-NIYIQLATMFLILVVIVLIFAMVIKFQGVFKAYA 2592
Query 3053 HVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPI 3112
+V L+++++ +LC+ S L + V Y Y + + + + + H F I
Sbjct 2593 TIVFTIMLVWVINAFVLCVHSYNSVLAVILLVLYCYASMVTSRNTAIIMHCWLVFTFGLI 2652
Query 3113 VPFWITAIYVFCISLKH---CHWFFNNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMYL 3168
VP W+ Y+ I + W + R +++G F ++ AA TF++ ++
Sbjct 2653 VPTWLACCYLGFILYMYTPLVFWCYGTTKNTRKLYDGNEFVGNYDLAAKSTFVIRGTEFV 2712
Query 3169 KLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQ 3228
KL +E ++ YL+ Y + KY+SG Y +A LA AL+ + NSG +V+Y
Sbjct 2713 KLTNEIG---DKFEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQYRNSGVEVVYT 2769
Query 3229 PPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAED 3288
PP+ SI + LQ+GF+K+ PS VE C+V V+ LNGLWL D++YCPRHV+
Sbjct 2770 PPRYSIGVSRLQAGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVL---GK 2826
Query 3289 MLNPNYEDLLIRKSNHSFLVQAGN-VQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQ 3347
+ D+L +NH F V N V L V+ ++ +L L+ +N +TPKYKFV+
Sbjct 2827 FSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKAN 2886
Query 3348 PGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMEL 3407
G +F++ Y G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+EL
Sbjct 2887 CGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLEL 2946
Query 3408 PTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVI-------NGDRWFL 3460
P +H GTDL G+FYG +VD + AQ D +T N++AWLYAA+I + +W L
Sbjct 2947 PNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKW-L 3005
Query 3461 NRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRT 3520
T ++ D+N A + P + + LSA TG+ V + + +
Sbjct 3006 ESTTVSIEDYNRWASDNGFTPFSTST--AITKLSAITGVDVCKLLRTIM-VKSAQWGSDP 3062
Query 3521 ILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWM-----LLTFLTSLLILVQST 3575
ILG EDE TP V Q GV Q F V+ W L FL L +V T
Sbjct 3063 ILGQYNFEDELTPESVFNQVGGVRLQSSF---VRKATSWFWSRCVLACFLFVLCAIVLFT 3119
Query 3576 QWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLAT------------ 3623
L F+V+ L +MA+ + VKH A++ FLLP+L T
Sbjct 3120 AVPLKFYVHAAVIL-----LMAVLFIS-FTVKHVMAYMDTFLLPTLITVIIGVCAEVPFI 3173
Query 3624 --------VAYFNMVYMPASWVMRIMTWLELADTSLSGYR-LKDCVMYASALVLLILMTA 3674
V + + Y P + ++ W+ L + ++ ++ C M + LL+L
Sbjct 3174 YNTLISQVVIFLSQWYDPVVF-DTMVPWMLLPLVLYTAFKCVQGCYMNSFNTSLLMLYQ- 3231
Query 3675 RTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARA 3734
+ ++T N +T + GN W L + + L
Sbjct 3232 ---FMKLGFVIYTSSNTLTAYTE---GN--------WELFFELVHTIVLANVSSNSLIGL 3277
Query 3735 IVFVCVE----YYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDY 3790
IVF C + Y + L +M+ +G+ C CYFGL+ +N+ F LTLG Y++
Sbjct 3278 IVFKCAKWMLYYCNATYFNNYVLMAVMV--NGIGWLCTCYFGLYWWVNKVFGLTLGKYNF 3335
Query 3791 LVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLL 3850
VS ++RYM + PPK+ + F NI + GIGG + +ATVQSK+SDVKCT+VVL+
Sbjct 3336 KVSVDQYRYMCLHKVNPPKTVWEVFTTNILIQGIGGDRVLPIATVQSKLSDVKCTTVVLM 3395
Query 3851 SVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEE 3910
+L +L VE++SK+ A V+LHN IL + D E + ++ +L L + +D+ C++
Sbjct 3396 QLLTKLNVEANSKMHAYLVELHNKILASDDVGECMDNLLGMLITLFCIDSTIDLGEYCDD 3455
Query 3911 MLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKS 3966
+L LQ++ EFS +PSYA Y A+ YE+ +A+ G ++ L +K+ N+AKS
Sbjct 3456 ILKRSTVLQSVTQEFSHIPSYAEYERAKSIYEKVLADSKNGGVTQQELAAYRKAANIAKS 3515
Query 3967 EFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNII 4026
FDRD A+Q+KL+ MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K+D++ LN +
Sbjct 3516 VFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLF 3575
Query 4027 NNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIV 4086
+ A G VPL +P+ + KL +V+PD T+ +G TY++ +W I V DAD +
Sbjct 3576 DQANSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDCVTDADGTEL 3635
Query 4087 QLSEINMD-----NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQMSCAAGTTQT 4138
+ + N+AWPL V R V LQNNEL P ++ +C AG Q
Sbjct 3636 HPTSTGSGLTYCISGDNIAWPLKVNLTRNGHNKVDVALQNNELMPHGVKTKACVAGVDQA 3695
Query 4139 ACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPK 4198
C+ ++ YY + G V A+ S + +LK A F G IY +L+PPC+F
Sbjct 3696 HCSVES-KCYYTSISGSSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDPPCKFGMKVGD 3753
Query 4199 GPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFCAFAVDPAKAY 4257
+V YLYFIK ++ RGMVLG+++ V LQ+ G+ TE +LS C+FAVDPA Y
Sbjct 3754 KVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLCSFAVDPADTY 3813
Query 4258 KDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHP--- 4314
Y+A+G QP+ NCVKML H G+G AIT P DQ+S+GGAS CLYCR HI HP
Sbjct 3814 CKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYCRAHIAHPGGA 3873
Query 4315 -NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP------- 4366
N G C KG +VQIPTT DPVGF LRN VCTVC W GYGC CD LR+P
Sbjct 3874 GNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSLRQPKPSVQSV 3932
Query 4367 LMQSADASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAKFLKTNCCRFQ 4426
+ S +LNRV G S ARL P G DVV RAFD+ N++ AG + LK NC RFQ
Sbjct 3933 AVASGFDKNYLNRVRGSSEARLIPLANGCDPDVVKRAFDVCNKESAGMFQNLKRNCARFQ 3992
Query 4427 E----KDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFKFRVDGDMVPH 4482
E +D DSYFVVK+ T SNY+HE+ Y +K A HDFF F + + +
Sbjct 3993 EVRDTEDGNLEYCDSYFVVKQTTPSNYEHEKACYEDLKS-EVTADHDFFVFNKN---IYN 4048
Query 4483 ISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDD---DYF-NKKDWYDFVENP 4538
ISRQRLTKYTM D YALRHFD +C+ LKEILVTY C +D +F KDWYD +ENP
Sbjct 4049 ISRQRLTKYTMMDFCYALRHFDPKDCEVLKEILVTYGCIEDYHPKWFEENKDWYDPIENP 4108
Query 4539 DILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDFGDFVQVAPGC 4598
+ A +G VR++LL ++F + M + G VGV+TLDNQDLNG +YDFGDF + APG
Sbjct 4109 KYYAMLAKMGPIVRRALLNAIEFGNLMVEKGYVGVITLDNQDLNGKFYDFGDFQKTAPGA 4168
Query 4599 GVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEERLCLFDRYFKY 4658
GVP+ D+YYS +MPI+ +T ALA E + + D+ K +DLLKYD+TEE+ LF +YFKY
Sbjct 4169 GVPVFDTYYSYMMPIIAMTDALAPERYFEYDVHKGYKSYDLLKYDYTEEKQDLFQKYFKY 4228
Query 4659 WDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFR 4718
WDQ YHPNC +C DDRC++HCANFN+LFST+ P TSFG L RK+FVDGVPF+ + GYH +
Sbjct 4229 WDQEYHPNCRDCSDDRCLIHCANFNILFSTLVPQTSFGNLCRKVFVDGVPFIATCGYHSK 4288
Query 4719 ELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQT 4778
ELGV+ NQD + S++ +L+ + DPA+ + N L+D RT+CFSV AL + + QT
Sbjct 4289 ELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLVGTSNKLVDLRTSCFSVCALASGITHQT 4348
Query 4779 VKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQL 4838
VKPG+FNKDFYDFA G FKEGSS+ LKHFF+ Q GNAAI+DYDYYRYN PTM DIRQL
Sbjct 4349 VKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFYPQTGNAAINDYDYYRYNRPTMFDIRQL 4408
Query 4839 LFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFA 4898
LF +EV KYF+CY+GGCI A+QV+VNNLDKSAG+PFNK+GKARLYY+ MS E+QD LF
Sbjct 4409 LFCLEVTSKYFECYEGGCIPASQVVVNNLDKSAGYPFNKFGKARLYYE-MSLEEQDQLFE 4467
Query 4899 YTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVI 4958
TK+NV+PTITQMNLKYAISAKNRARTVAGVSI STMTNRQFHQK+LKSI TR A VVI
Sbjct 4468 STKKNVLPTITQMNLKYAISAKNRARTVAGVSILSTMTNRQFHQKILKSIVNTRNAPVVI 4527
Query 4959 GTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLS 5018
GT+KFYGGW NML+ + VE P LMGWDYPKCDRAMPN+LRI ASLVLARKH CC S
Sbjct 4528 GTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKCDRAMPNLLRIAASLVLARKHTNCCTWS 4587
Query 5019 HRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLS 5078
R YRL NECAQVLSE V+ G +YVKPGGTSSGDATTAYANSVFNI QA +ANV LLS
Sbjct 4588 ERVYRLYNECAQVLSETVLATGGIYVKPGGTSSGDATTAYANSVFNIIQATSANVARLLS 4647
Query 5079 TDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSN 5138
I +++LQ+ LY+ +YR + D FV++FY+YL K+FS+MILSDD VVCYN+
Sbjct 4648 VITRDIVYDDIKSLQYELYQQVYRRVNFDPAFVEKFYSYLCKNFSLMILSDDGVVCYNNT 4707
Query 5139 YAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYL 5198
A QGLVA I F+ VLYYQNNVFM+++KCW E DL KGPHEFCSQHTMLV+ + YL
Sbjct 4708 LAKQGLVADISGFREVLYYQNNVFMADSKCWVEPDLEKGPHEFCSQHTMLVEVDGEPRYL 4767
Query 5199 PYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIR 5258
PYPDPSRIL A FVDD+ KT+ ++ER+++LAIDAYPL H N+EY VF + L YIR
Sbjct 4768 PYPDPSRILCACVFVDDLDKTESVAVMERYIALAIDAYPLVHHENEEYKKVFFVLLSYIR 4827
Query 5259 KLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCG 5318
KL+ EL+ +ML YS ++ D S++WE EFYE MY T LQ+ G CV+CNSQT LRCG
Sbjct 4828 KLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYENMYRAPTTLQSCGVCVVCNSQTILRCG 4887
Query 5319 ACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKP 5378
CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C+ PGC DVT+LYLGGMSY+C +HKP
Sbjct 4888 NCIRKPFLCCKCCYDHVMHTDHKNVLSINPYICSQPGCGEADVTKLYLGGMSYFCGNHKP 4947
Query 5379 PISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAET 5438
+S PL +NG VFG+Y+ C GS+NV DFN +AT +W+ YILAN C + L+ FAAET
Sbjct 4948 KLSIPLVSNGTVFGIYRANCAGSENVDDFNQLATTNWSTVEPYILANRCVDSLRRFAAET 5007
Query 5439 LKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGE 5498
+KATEE K + A VREVLSDREL LSWE GK RPPLNRNYVFTG+ T+ SKVQ+G+
Sbjct 5008 VKATEELHKQQFASAEVREVLSDRELILSWEPGKTRPPLNRNYVFTGFHFTRTSKVQLGD 5067
Query 5499 YTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLN 5558
+TFEKG+ D V YR T+T KL+VGD FVLTSH V+ L APTL PQ+ + R L P +
Sbjct 5068 FTFEKGEGKDVVYYRATSTAKLSVGDIFVLTSHNVVSLIAPTLCPQQTFSRFVNLRPNVM 5127
Query 5559 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDAL 5618
+ F +N+ Y VG QK +T+QGPPG+GKSHFAIGLA Y+ +AR+V+TACSHAAVDAL
Sbjct 5128 VPACFVNNIPLYHLVGKQKRTTVQGPPGSGKSHFAIGLAAYFSNARVVFTACSHAAVDAL 5187
Query 5619 CEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEIS 5678
CEKA K+L +D C+RI+P R ++CF KFK N T ++Y+F T+NALPE + DI++ DE+S
Sbjct 5188 CEKAFKFLKVDDCTRIVPQRTTIDCFSKFKANDTGKKYIFSTINALPEVSCDILLVDEVS 5247
Query 5679 MATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMF 5738
M TNY+LS +N ++ ++ VY+GDPAQLPAPRTLL G+L P+ +N V LM + PD+F
Sbjct 5248 MLTNYELSFINGKINYQYVVYVGDPAQLPAPRTLLN-GSLSPKDYNVVTNLMVCVKPDIF 5306
Query 5739 LGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKG---VITHDVSSAINRPQIG 5795
L C RCP EIVDTVS LVYD K A+ +S QCFK+ + H+ SA N Q+
Sbjct 5307 LAKCYRCPKEIVDTVSTLVYDGKFIANNPESRQCFKVIVNNGNSDVGHESGSAYNITQLE 5366
Query 5796 VVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAH 5855
V++F+ RN WR+A FISPYN+ N A ++LGL QTVDSSQGSEYDYVIF T ++ H
Sbjct 5367 FVKDFVCRNKEWREATFISPYNAMNQRAYRMLGLNVQTVDSSQGSEYDYVIFCVTADSQH 5426
Query 5856 SCNVNRFNVAITRAKIGILCIMSDRD-LYDKLQFTSLEIPRRNVATLQAENVTGLFKDCS 5914
+ N+NRFNVA+TRAK GIL +M RD LY L+F L+ +VA+LQ TGLFK C+
Sbjct 5427 ALNINRFNVALTRAKRGILVVMRQRDELYSALKFIELD----SVASLQG---TGLFKICN 5479
Query 5915 KIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIP--KDMTYRRLISMMGFKMNYQVNGYP 5972
K +G+HP A T ++ +K + + ++TY+ LIS++GFKM+ V G
Sbjct 5480 KEFSGVHPAYAVTTKALAATYKVNDELAALVNVEAGSEITYKHLISLLGFKMSVNVEGCH 5539
Query 5973 NMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAVPTGYVDTENN 6032
NMFITR+EAIR+VR W+GFDVE HA +GTNLP Q+GFSTG + V P G VDT
Sbjct 5540 NMFITRDEAIRNVRGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVTPEGLVDTSIG 5599
Query 6033 TEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDRVVFVLWAHGF 6092
F VN+K PPG+QF HL L PW+VVR +IVQML+D L +SD VVFV W HG
Sbjct 5600 NNFEPVNSKAPPGEQFNHLRALFKSAKPWHVVRPRIVQMLADNLCNVSDCVVFVTWCHGL 5659
Query 6093 ELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPFMIDVQQWGFT 6152
ELT+++YFVKIG ++ C C RAT F++ + YACW H +GFD+VYNP ++D+QQWG++
Sbjct 5660 ELTTLRYFVKIGKDQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPLLVDIQQWGYS 5718
Query 6153 GNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIGDELRVNSACR 6212
GNLQ NHD HC VHG+AHVAS DAIMTRCLA++ F + V+W + YP I +E VNS+CR
Sbjct 5719 GNLQFNHDLHCNVHGHAHVASADAIMTRCLAINNAFCQDVNWDLTYPHIANEDEVNSSCR 5778
Query 6213 KVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKAYKIEELFYSY 6272
+Q M + + + A K V++DIGNPK IKCV + ++ ++FYD P + E Y Y
Sbjct 5779 YLQRMYLNACVDALKVNVVYDIGNPKGIKCVRRGDLNFRFYDKNPIVPNVKQFE---YDY 5835
Query 6273 ATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPA 6332
H DKF DG+C+FWNCNVD YP N++VCR+DTR LS NLPGC+GGSLYVNKHAFHTP
Sbjct 5836 NQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLYVNKHAFHTPK 5895
Query 6333 FDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANE 6392
FD+++F NLK +PFF+Y SPCE+ V+ D V L + CIT+CN+GGAVC+ HA
Sbjct 5896 FDRTSFRNLKAMPFFFYDSSPCETIQLDGVAQ-DLVSLATKDCITKCNIGGAVCKKHAQM 5954
Query 6393 YRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKGHFDGHAGEAP 6452
Y ++ +YN ++AGF+ W+ F+ YNLW +F+ LQS++N+AYN+ GH+D AGE P
Sbjct 5955 YADFVTSYNAAVTAGFTFWVTNNFNPYNLWKSFSALQSIDNIAYNMYKGGHYDAIAGEMP 6014
Query 6453 VSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILNNLGVDIAANT 6512
+ + V+ G++ +F N+T LP +VAFEL+AKRNI+ +P +IL LGVD+
Sbjct 6015 TIVTGDKVFVIDQGVEKAVFFNQTILPTSVAFELYAKRNIRTLPNNRILKGLGVDVTNGF 6074
Query 6513 VIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDLFRNARNGVLI 6572
VIWDY + P + +T+ VC TDI + L VL+D R G F A N VL+
Sbjct 6075 VIWDYTNQTPLYRNTVKVCAYTDIEP-------NGLIVLYDDRY-GDYQSFLAADNAVLV 6126
Query 6573 TEGSVKGLTPSKGPAQASV-NGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLED 6631
+ K + + P+ V NG+ L + +K+V+G LP T TQ R E
Sbjct 6127 STQCYKRYSYVEIPSNLLVQNGIPLKDGA---NLYVYKRVNGAFVTLPNTLNTQGRSYET 6183
Query 6632 FKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSP 6691
F+PRS +E DFL+++ + F+++Y E +HI+YG+ QLGGLH +IG+ + + +
Sbjct 6184 FEPRSDVERDFLDMSEESFVEKYGKE-LGLQHILYGEVDKPQLGGLHTVIGMCRLLRANK 6242
Query 6692 LKLEDFIPMDST-VKNYFITDAQTGSSKCVCSVIDLLLDDFV----EIIKSQDLSVISKV 6746
L + DS ++NYF+ A GS K VC+V+DLLLDDF+ I+K + SKV
Sbjct 6243 LNAKSVTNSDSDVMQNYFVL-ADNGSYKQVCTVVDLLLDDFLELLRNILKEYGTN-KSKV 6300
Query 6747 VKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRMLLEKCDLQNYG 6806
V V+IDY I+FM W +DG ++T YP+LQ++ W G MP LYK+Q ++E C++ NYG
Sbjct 6301 VTVSIDYHSINFMAWFEDGIIKTCYPQLQSA--WTCGYNMPELYKVQNCVMEPCNIPNYG 6358
Query 6807 ENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPT 6866
+P GIMMNVAKYTQLCQYL+ T+ VP+NMRV+HFGAGSDKGVAPG+ VL+QWLP
Sbjct 6359 VGIALPSGIMMNVAKYTQLCQYLSKTTMCVPHNMRVMHFGAGSDKGVAPGSTVLKQWLPE 6418
Query 6867 GTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY---DPRTKHVTK-ENDSKE 6922
GTLLVD+D+ D+VSDA +++ DC T +K+DL+ISDMY D + KH N+ +
Sbjct 6419 GTLLVDNDIVDYVSDAHVSVLSDCNKYKTEHKFDLVISDMYTDNDSKRKHEGVIANNGND 6478
Query 6923 GFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLI 6982
F YL F++ LALGGS AVK+TE SW+ LY + +WWT F T VNASSSEAFL+
Sbjct 6479 DVFIYLSSFLRNNLALGGSFAVKVTETSWHEVLYDIAQDCAWWTMFCTAVNASSSEAFLV 6538
Query 6983 GANYLGKP-KEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQ 7041
G NYLG K ++ G T+HANYIFWRN N +Q S+YS+FD++KF L+L+ T V++LK Q
Sbjct 6539 GVNYLGASEKVKVSGKTLHANYIFWRNCNYLQTSAYSIFDVAKFDLRLKATPVVNLKTEQ 6598
Query 7042 INDMIYSLLEKGRLIIRENNRVVVSSDILV 7071
D++++L++ G+L++R+ +SD V
Sbjct 6599 KTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6628
Score = 208 bits (529), Expect = 2e-51, Method: Composition-based stats.
Identities = 84/353 (24%), Positives = 136/353 (39%), Gaps = 49/353 (14%)
Query 878 EAVVKTL-QPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDA 936
E VK L Q V D+L + G +D A L S + F + + A
Sbjct 870 EGAVKALPQKVIDVLGDWGEAVD----AQEQLCQQESTRVISEKSVEGFTGSCDAMAEQA 925
Query 937 ECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEE-------EEEDWLDDTTEQS 989
EE+EI E ++D P + ET +E +E+ + E+
Sbjct 926 IVEEQEIVPVVEQ---SQDVVVFTPADLEVVKETAEEVDEFILISAVPKEEVVSQEKEEP 982
Query 990 EIEPEPEPTPEEPVN----------------QFTGYLKLTDNVAIKCVDIVKEAQSANPM 1033
++E EP + +F Y ++A+ I K
Sbjct 983 QVEQEPTLVVKAQREKKAKKFKVKPATCEKPKFLEYKTCVGDLAVV---IAKALDEFKEF 1039
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCL 1093
IVNAAN H+ HGGGVA A+ + DY+K +GP + +C+
Sbjct 1040 CIVNAANEHMSHGGGVAKAIADFCGPDFVEYCADYVKKHGPQQ---KLVTPSFVKGIQCV 1096
Query 1094 -HVVGPNLNAGEDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPLQSLQVCVQTVRTQ 1150
+VVGP + L AAY++ ++ + P+LS+GIFG ++ + +R
Sbjct 1097 NNVVGPRHGDSNLREKLVAAYKSVLVGGVVNYVVPVLSSGIFGVD----FKISIDAMRE- 1151
Query 1151 VYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVD 1203
+ + L + +++D KQ+ TED + +SVV KP D
Sbjct 1152 AFKGCAIRVLLFSLSQEHIDYFDATC---KQKTIYLTEDG-VKYRSVVLKPGD 1200
Score = 42.7 bits (99), Expect = 0.20, Method: Composition-based stats.
Identities = 95/572 (17%), Positives = 161/572 (28%), Gaps = 89/572 (16%)
Query 786 NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEV--QGYKNVRIT 843
N + KD+ Y L A N V + G K VTFGE TV E+ ++++
Sbjct 643 NYMFFRFKKDENIYYTPMSQLGAINVVCKAGG----KTVTFGETTVQEIPPPDVVFIKVS 698
Query 844 FELD-ERVDKVLNEKCSV-YTVESGTEVTEFACVVAEAVVKTLQPV-----------SDL 890
E E + + + VE+ V + VV E + L+ L
Sbjct 699 IECCGEPWNTIFKKAYKEPIEVETDLTVEQLLSVVYEKMCDDLKLFPEAPEPPPFENVTL 758
Query 891 LTNMGIDLDEWSVATF-YLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEH 949
+ G DLD Y ++ ++ + EE D E EE DE +
Sbjct 759 VDKNGKDLDCIKSCHLIYRDYESDDDIEEEDAEECDTDSGDAEECDTNLECEEEDEDTKV 818
Query 950 EYGTED---DYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQF 1006
+D + LPL+ S + ++ D ++
Sbjct 819 LALIQDPASNKYPLPLDDDYSVYNGCIVHKDALDVVN----------------------- 855
Query 1007 TGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESD 1066
L + + ++ VI + G A A Q+ES
Sbjct 856 ---LPSGEETFVVNNCFEGAVKALPQKVI------DVLGDWGEA---VDAQEQLCQQEST 903
Query 1067 DYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQL-----LKAAYENFNSQDI 1121
I GSC + +V P + +D+ + L+ E D
Sbjct 904 RVISEKSVEGFTGSCDAMAEQAIVEEQEIV-PVVEQSQDVVVFTPADLEVVKETAEEVDE 962
Query 1122 LLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQ 1181
+ L+SA + V + ++ V K P
Sbjct 963 FI--LISA----VPKE-------EVVSQEKEEPQVEQEPTLVVKAQREKKAKKFKVKPAT 1009
Query 1182 EEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYH 1241
E P + KT + + K + + + +
Sbjct 1010 CEKPKFLEYKTCVGDLAVVIAKALDEFK---EFCIVNAANEH-----MSHGGGVAKAIAD 1061
Query 1242 DSQNMLRGEDMSFLEKDAPYM--VGDVITSGD--ITCVVIPSKKAGGTTEMLSRALKKVP 1297
+++K P V G + VV P E L A K V
Sbjct 1062 FCGPDFVEYCADYVKKHGPQQKLVTPSFVKGIQCVNNVVGPRHGDSNLREKLVAAYKSVL 1121
Query 1298 VDEYITTYPGQGCAGYTLEEAKTALKKCKSAF 1329
V + +G + K ++ + AF
Sbjct 1122 VGGVVNYVVPVLSSGIFGVDFKISIDAMREAF 1153
>sp|P0C6Y1|R1AB_IBVB Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=rep PE=1
SV=1
Length=6629
Score = 6360 bits (16501), Expect = 0.0, Method: Composition-based stats.
Identities = 2348/5680 (41%), Positives = 3253/5680 (57%), Gaps = 376/5680 (7%)
Query 1541 EVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPS 1600
K ++ T D + ++ + G QFG Y V + E K +P+
Sbjct 1174 TCKQKTIYLTEDGVKYRSIVLKPGDSLG-QFGQVYAKNKIVFTA---DDVEDKEILYVPT 1229
Query 1601 DDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLAL 1660
D E Y+ LD Y+ L +KW ++W D NC++SS ++ L
Sbjct 1230 TDKSILE----YYGLDAQKYVIYLQTL--AQKWNVQYRDNFLILEWRDGNCWISSAIVLL 1283
Query 1661 QQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLES 1720
Q +++F L EA+ + GD +F A A VG+ D + +L +H + +
Sbjct 1284 QAAKIRFKG-FLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFSDANWLLANLAEHFDADY 1342
Query 1721 AKRVLNV-VCKHCGQKTTTLTGVEAVM-YMGTLSYDNLKTGVSIPCVCGRDATQYLVQQE 1778
L V +CG K+ L G+EA + + + + KT S CG + T +++
Sbjct 1343 TNAFLKKRVSCNCGIKSYELRGLEACIQPVRATNLLHFKTQYSNCPTCGANNTDEVIEAS 1402
Query 1779 SSFVMMSAP--PAEYKLQQGTFLCANEYTGNYQCGH-YTHITAKETLYRIDGAHLTKMSE 1835
++++ A PA + + + G+ GH YT D +
Sbjct 1403 LPYLLLFATDGPATVDCDEDA-VGTVVFVGSTNSGHCYTQAAG----QAFDNLAKDRKFG 1457
Query 1836 YKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQ 1895
K P Y ++ K ++ +
Sbjct 1458 KKSPYITAMYTRFAFKNETSLPVAKQSKGKSKSVKEDVSNL------------------A 1499
Query 1896 PLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSAS 1955
ASFDN D Q + L V PD ++ Y +
Sbjct 1500 TSSKASFDNL----------TDFEQW--YDSNIYESLKVQESPD--------NFDKYVSF 1539
Query 1956 FKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDN 2015
T + + P T +R + S + + F DT
Sbjct 1540 ------------------TTKEDSKLPLTLKVRGIKSVVDFRSKDGFIYKLTPDTD---- 1577
Query 2016 LACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
S+ P V++ + +K V GN ++ L
Sbjct 1578 --ENSKAPVYYPVLDAIS---------LKAIWVEGNANFVVGHPNY-YSKSLHIPTFWEN 1625
Query 2076 Y---------VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQA 2126
+ ++ + + L+ IA V S + +G+A
Sbjct 1626 AENFVKMGDKIGGVTMGLWRAEHLNKP---NLERIFNIAKKAIVGSSVVTTQCGKLIGKA 1682
Query 2127 AITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKL 2186
A ++ R + + + + F + + + K + +
Sbjct 1683 ATFIADKVGGGVVRNITDSIKGLCGITRG--HFERKMSPQF--------LKTLMFFLFYF 1732
Query 2187 CLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVREL 2246
+ + V S K + LL++ S + VL S C ++
Sbjct 1733 LKASVKSVVASYKTVLCKVVLATLLIVWFVYTSNPVMFTGIRVL-DFLFEGSLCGPYKDY 1791
Query 2247 YLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVL 2306
+S +V + +C F C +CL DSL Y +++ YK + G W
Sbjct 1792 GKDSFDV--LRYCADDFICRVCLHDKDSLHLYKHAYSVE---QVYKDAAS--GFIFNWNW 1844
Query 2307 AYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--------WLMWFIISIVQMAPVSAMV 2358
Y++F F V Y + + NS +L WF V +
Sbjct 1845 LYLVFLILFVKPVAGF---VIICYCVKYLVLNSTVLQTGVCFLDWF---------VQTVF 1892
Query 2359 RMYIFFASFYYIWKSYV-----HIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYV 2413
+ F + +Y W Y H + C TC +C + R+ R E + +V G K+ +V
Sbjct 1893 SHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHV 1952
Query 2414 YANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAV 2473
Y N G FCK HNW C NCD + +TF+S EVA +LS + KR + PT + ++VD +
Sbjct 1953 YTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKPTAYAYHVVDEACL 2012
Query 2474 KNGALHLYFD-KAGQKTYERHPLSHFVNLDNL-RANNTKGSLPINVIVFDGKSKCDESA- 2530
+ ++L + K + F D L +A K +L I DG C+ +
Sbjct 2013 VDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSA 2072
Query 2531 -----SKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEK 2585
+K+A++YY+Q +C+PIL+LDQAL + VS + D S+ SV
Sbjct 2073 HALEEAKNAAIYYAQYLCKPILILDQALYEQL-VVEPVSKSVIDKVCSILSSIISVD--- 2128
Query 2586 LKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGD 2645
TA G D +LS ++ ++ H+ D++ TGD
Sbjct 2129 ------TAALNYKAGTLRDALLSI-------------TKDEEAVDMAIFCHNHDVDYTGD 2169
Query 2646 SCNNFMLTY-NKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRK 2704
N + +Y +TPRD G I+ +A N +V + ++W + + LS+ K
Sbjct 2170 GFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAP--PVVWKFSELIKLSDSCLK 2227
Query 2705 QIRSAAKKNNIPFRLTCATTRQVVNVITTKISL--KGGKIVS---TCFKLMLKATLLCVL 2759
+ SA K+ + F +T + +QV+ T K+ + K G IVS CFK K L+ +
Sbjct 2228 YLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKCFKSYFKWLLIFYI 2287
Query 2760 AALVC---YIVMPVHTLSIHDGY----TNEIIGYKAIQDGVTRDIISTDDCFANKHAGFD 2812
C Y M V +H Y T + G+K I GV R+I+ D CF+NK FD
Sbjct 2288 LFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVPEDTCFSNKFVNFD 2347
Query 2813 AWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAING-DFLH---------FL 2862
A++ G Y N ++CP+V A+I + G + G+PG V ++G F+H ++
Sbjct 2348 AFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMFIHMTQTERKPWYI 2403
Query 2863 PRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD-TNLLEGSIS 2921
P F+ + YT +I F TS + +A C ++ A P YC++ N G++
Sbjct 2404 PTWFNRE-IVGYTQDSIITEGSFYTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALP 2461
Query 2922 YSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRW 2981
+ + P Y +G + P L + VV YCR CE + G C+S + +W
Sbjct 2462 FGSIIPHRVYFQPNGVRLIVPQQILH-TPYVVKFVSDSYCRGSVCEYTRPGYCVSLNPQW 2520
Query 2982 VLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYF 3041
VL N+ Y + GVFCG L+ ++ + V ++ + +I ++V
Sbjct 2521 VLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLATMFLILVVVVLIFAMV 2579
Query 3042 MKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLA 3101
+KF+ VF Y V L+++++ ILC+ S L + V Y Y + + + +
Sbjct 2580 IKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLYCYASLVTSRNTVIIM 2639
Query 3102 HLQWFAMFSPIVPFWITAIYVFCISLKH---CHWFFNNYLRKRVMFNGVTF-STFEEAAL 3157
H F IVP W+ Y+ I + W + R +++G F ++ AA
Sbjct 2640 HCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKLYDGNEFVGNYDLAAK 2699
Query 3158 CTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALND 3217
TF++ ++KL +E ++ YL+ Y + KY+SG Y +A LA AL+
Sbjct 2700 STFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQ 2756
Query 3218 FSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVY 3277
+ NSG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+ LNGLWL DT+Y
Sbjct 2757 YRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIY 2816
Query 3278 CPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAG-NVQLRVIGHSMQNCLLRLKVDTSNP 3336
CPRHV+ + D+L +NH F V V L V+ ++ +L L+ +N
Sbjct 2817 CPRHVL---GKFSGDQWNDVLNLANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANA 2873
Query 3337 KTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDC 3396
+TPKYKF++ G +F++ Y G+ G+Y MR N TI+ SFL G+CGSVGFNI+
Sbjct 2874 ETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGV 2933
Query 3397 VSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGD 3456
V+F YMHH+ELP +H GTDL G+FYG +VD + AQ D +T N++AWLYAA+I+
Sbjct 2934 VNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVK 2993
Query 3457 RW------FLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
+L T +++D+N A + P + + LSA TG+ V + +
Sbjct 2994 ESSFSLPKWLESTTVSVDDYNKWAGDNGFTPFSTST--AITKLSAITGVDVCKLLRTIM- 3050
Query 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWM-----LLTFL 3565
+ + G ILG EDE TP V Q GV Q F V+ W L FL
Sbjct 3051 VKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSF---VRKATSWFWSRCVLACFL 3107
Query 3566 TSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLAT-- 3623
L +V T L F+VY L +MA+ + VKH A++ FLLP+L T
Sbjct 3108 FVLCAIVLFTAVPLKFYVYAAVIL-----LMAVLFIS-FTVKHVMAYMDTFLLPTLITVI 3161
Query 3624 ------------------VAYFNMVYMPASWVMRIMTWLELADTSLSGYR-LKDCVMYAS 3664
V + + Y P + ++ W+ L + ++ ++ C M +
Sbjct 3162 IGVCAEVPFIYNTLISQVVIFLSQWYDPVVF-DTMVPWMFLPLVLYTAFKCVQGCYMNSF 3220
Query 3665 ALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGV 3724
LL+L + ++T N +T + GN W L +
Sbjct 3221 NTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN--------WELFFELVHTTVLA 3265
Query 3725 VTTIMFLARAIVFVCVE----YYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
+ L VF C + Y ++ L +M+ +G+ C CYFGL+ +N+
Sbjct 3266 NVSSNSLIGLFVFKCAKWMLYYCNATYLNNYVLMAVMV--NCIGWLCTCYFGLYWWVNKV 3323
Query 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
F LTLG Y++ VS ++RYM + PPK+ + F NI + GIGG + +ATVQ+K+S
Sbjct 3324 FGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLPIATVQAKLS 3383
Query 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
DVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E + ++ +L L +
Sbjct 3384 DVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGECMDNLLGMLITLFCIDS 3443
Query 3901 AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYE----QAVANGDSEVVLKK 3956
+D++ C+++L LQ++ EFS +PSYA Y A+ YE + G ++ L
Sbjct 3444 TIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAA 3503
Query 3957 LKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRK 4016
+K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K
Sbjct 3504 YRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKK 3563
Query 4017 LDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQ 4076
+D++ LN + + A G VPL +P+ + KL +V+PD T+ +G TY++ +W I
Sbjct 3564 IDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNID 3623
Query 4077 QVVDADSKIVQLSEINMD-----NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQ 4128
V+DAD + + + N+AWPL V R V LQNNEL P ++
Sbjct 3624 TVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNKVDVVLQNNELMPHGVKT 3683
Query 4129 MSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEP 4188
+C AG Q C+ ++ YY N G V A+ S + +LK A F G IY +L+P
Sbjct 3684 KACVAGVDQAHCSVES-KCYYTNISGNSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDP 3741
Query 4189 PCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFC 4247
PC+F +V YLYFIK ++ RGMVLG+++ V LQ+ G+ TE +LS C
Sbjct 3742 PCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLC 3801
Query 4248 AFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYC 4307
+FAVDPA Y Y+A+G QP+ NCVKML H G+G AIT P DQ+S+GGAS CLYC
Sbjct 3802 SFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYC 3861
Query 4308 RCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQL 4363
R HI HP N G C KG +VQIPTT DPVGF LRN VCTVC W GYGC CD L
Sbjct 3862 RAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSL 3920
Query 4364 REPLMQSAD-------ASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAK 4416
R+P +LNRV G S ARL P +G DVV RAFD+ N++ AG +
Sbjct 3921 RQPKSSVQSVAGASDFDKNYLNRVRGSSEARLIPLASGCDPDVVKRAFDVCNKESAGMFQ 3980
Query 4417 FLKTNCCRFQE----KDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFK 4472
LK NC RFQE +D LDSYFVVK+ T SNY+HE++ Y +K A HDFF
Sbjct 3981 NLKRNCARFQELRDTEDGNLEYLDSYFVVKQTTPSNYEHEKSCYEDLKS-EVTADHDFFV 4039
Query 4473 FRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDD---DYF-NK 4528
F + + +ISRQRLTKYTM D YALRHFD +C+ LKEILVTY C +D +F
Sbjct 4040 FNKN---IYNISRQRLTKYTMMDFCYALRHFDPKDCEVLKEILVTYGCIEDYHPKWFEEN 4096
Query 4529 KDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDF 4588
KDWYD +EN + A +G VR++LL ++F + M + G VGV+TLDNQDLNG +YDF
Sbjct 4097 KDWYDPIENSKYYVMLAKMGPIVRRALLNAIEFGNLMVEKGYVGVITLDNQDLNGKFYDF 4156
Query 4589 GDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEER 4648
GDF + APG GVP+ D+YYS +MPI+ +T ALA E + + D+ K +DLLKYD+TEE+
Sbjct 4157 GDFQKTAPGAGVPVFDTYYSYMMPIIAMTDALAPERYFEYDVHKGYKSYDLLKYDYTEEK 4216
Query 4649 LCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVP 4708
LF +YFKYWDQ YHPNC +C DDRC++HCANFN+LFST+ P TSFG L RK+FVDGVP
Sbjct 4217 QELFQKYFKYWDQEYHPNCRDCSDDRCLIHCANFNILFSTLIPQTSFGNLCRKVFVDGVP 4276
Query 4709 FVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVA 4768
F+ + GYH +ELGV+ NQD + S++ +L+ + DPA+ + N L+D RT+CFSV
Sbjct 4277 FIATCGYHSKELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLVGTSNNLVDLRTSCFSVC 4336
Query 4769 ALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYN 4828
ALT+ + QTVKPG+FNKDFYDFA G FKEGSS+ LKHFF+ Q GNAAI+DYDYYRYN
Sbjct 4337 ALTSGITHQTVKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFYPQTGNAAINDYDYYRYN 4396
Query 4829 LPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSM 4888
PTM DI QLLF +EV KYF+CY+GGCI A+QV+VNNLDKSAG+PFNK+GKARLYY+ M
Sbjct 4397 RPTMFDICQLLFCLEVTSKYFECYEGGCIPASQVVVNNLDKSAGYPFNKFGKARLYYE-M 4455
Query 4889 SYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSI 4948
S E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI STMTNRQFHQK+LKSI
Sbjct 4456 SLEEQDQLFEITKKNVLPTITQMNLKYAISAKNRARTVAGVSILSTMTNRQFHQKILKSI 4515
Query 4949 AATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLA 5008
TR A+VVIGT+KFYGGW NML+ + VE P LMGWDYPKCDRAMPN+LRI ASLVLA
Sbjct 4516 VNTRNASVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKCDRAMPNLLRIAASLVLA 4575
Query 5009 RKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQA 5068
RKH CC+ S R YRL NECAQVLSE V+ G +YVKPGGTSSGDATTAYANSVFNI QA
Sbjct 4576 RKHTNCCSWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSSGDATTAYANSVFNIIQA 4635
Query 5069 VTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILS 5128
+ANV LLS I +++LQ+ LY+ +YR + D FV++FY+YL K+FS+MILS
Sbjct 4636 TSANVARLLSVITRDIVYDNIKSLQYELYQQVYRRVNFDPAFVEKFYSYLCKNFSLMILS 4695
Query 5129 DDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTML 5188
DD VVCYN+ A QGLVA I F+ VLYYQNNVFM+++KCW E DL KGPHEFCSQHTML
Sbjct 4696 DDGVVCYNNTLAKQGLVADISGFREVLYYQNNVFMADSKCWVEPDLEKGPHEFCSQHTML 4755
Query 5189 VKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYAD 5248
V+ + YLPYPDPSRILGA FVDD+ KT+ ++ER+++LAIDAYPL H N+EY
Sbjct 4756 VEVDGEPKYLPYPDPSRILGACVFVDDVDKTEPVAVMERYIALAIDAYPLVHHENEEYKK 4815
Query 5249 VFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVL 5308
VF + L YIRKL+ EL+ +ML YS ++ D S++WE EFYE MY T LQ+ G CV+
Sbjct 4816 VFFVLLAYIRKLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYENMYRAPTTLQSCGVCVV 4875
Query 5309 CNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGG 5368
CNSQT LRCG CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C+ GC DVT+LYLGG
Sbjct 4876 CNSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYICSQLGCGEADVTKLYLGG 4935
Query 5369 MSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCT 5428
MSY+C +HKP +S PL +NG VFG+Y+ C GS+NV DFN +AT +W+ YILAN C+
Sbjct 4936 MSYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLATTNWSIVEPYILANRCS 4995
Query 5429 ERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRV 5488
+ L+ FAAET+KATEE K + A VREV SDREL LSWE GK RPPLNRNYVFTGY
Sbjct 4996 DSLRRFAAETVKATEELHKQQFASAEVREVFSDRELILSWEPGKTRPPLNRNYVFTGYHF 5055
Query 5489 TKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYV 5548
T+ SKVQ+G++TFEKG+ D V Y+ T+T KL+VGD FVLTSH V+ L APTL PQ+ +
Sbjct 5056 TRTSKVQLGDFTFEKGEGKDVVYYKATSTAKLSVGDIFVLTSHNVVSLVAPTLCPQQTFS 5115
Query 5549 RITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYT 5608
R L P + + + F +N+ Y VG QK +T+QGPPG+GKSHFAIGLA+Y+ SAR+V+T
Sbjct 5116 RFVNLRPNVMVPECFVNNIPLYHLVGKQKRTTVQGPPGSGKSHFAIGLAVYFSSARVVFT 5175
Query 5609 ACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETT 5668
ACSHAAVDALCEKA K+L +D C+RI+P R V+CF KFK N T ++Y+F T+NALPE +
Sbjct 5176 ACSHAAVDALCEKAFKFLKVDDCTRIVPQRTTVDCFSKFKANDTGKKYIFSTINALPEVS 5235
Query 5669 ADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCR 5728
DI++ DE+SM TNY+LS +N ++ ++ VY+GDPAQLPAPRTLL G+L P+ +N V
Sbjct 5236 CDILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRTLLN-GSLSPKDYNVVTN 5294
Query 5729 LMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKG---VITHDV 5785
LM + PD+FL C RCP EIVDTVS LVYD K A+ +S +CFK+ + H+
Sbjct 5295 LMVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRECFKVIVNNGNSDVGHES 5354
Query 5786 SSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYV 5845
SA N Q+ V++F+ RN WR+A+FISPYN+ N A ++LGL QTVDSSQGSEYDYV
Sbjct 5355 GSAYNTTQLEFVKDFVCRNKQWREAIFISPYNAMNQRAYRMLGLNVQTVDSSQGSEYDYV 5414
Query 5846 IFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRD-LYDKLQFTSLEIPRRNVATLQAE 5904
IF T ++ H+ N+NRFNVA+TRAK GIL +M RD LY L+FT L+ + +LQ
Sbjct 5415 IFCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALKFTELD----SETSLQG- 5469
Query 5905 NVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIP--KDMTYRRLISMMGF 5962
TGLFK C+K +G+HP A T ++ +K + + ++TY+ LIS++GF
Sbjct 5470 --TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNVEAGSEITYKHLISLLGF 5527
Query 5963 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAV 6022
KM+ V G NMFITR+EAIR+VR W+GFDVE HA +GTNLP Q+GFSTG + V
Sbjct 5528 KMSVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVT 5587
Query 6023 PTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDR 6082
P G VDT F VN+K PPG+QF HL L PW+V+R +IVQML+D L +SD
Sbjct 5588 PEGLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIRPRIVQMLADNLCNVSDC 5647
Query 6083 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPF 6142
VVFV W HG ELT+++YFVKIG E+ C C RAT F++ + YACW H +GFD+VYNP
Sbjct 5648 VVFVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPL 5706
Query 6143 MIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIG 6202
++D+QQWG++GNLQ NHD HC VHG+AHVAS DAIMTRCLA++ F + V+W + YP I
Sbjct 5707 LVDIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAINNAFCQDVNWDLTYPHIA 5766
Query 6203 DELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKA 6262
+E VNS+CR +Q M + + + A K V++DIGNPK IKCV + +V ++FYD P
Sbjct 5767 NEDEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRRGDVNFRFYDKNPIVRNV 5826
Query 6263 YKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLY 6322
+ E Y Y H DKF DG+C+FWNCNVD YP N++VCR+DTR LS NLPGC+GGSLY
Sbjct 5827 KQFE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLY 5883
Query 6323 VNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 6382
VNKHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+ D V L + CIT+CN+G
Sbjct 5884 VNKHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ-DLVSLATKDCITKCNIG 5942
Query 6383 GAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKG 6442
GAVC+ HA Y +++ +YN ++AGF+ W+ + + YNLW +F+ LQS++N+AYN+ G
Sbjct 5943 GAVCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSFSALQSIDNIAYNMYKGG 6002
Query 6443 HFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILN 6502
H+D AGE P I + V+ G++ +F N+TTLP +VAFEL+AKRNI+ +P +IL
Sbjct 6003 HYDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFELYAKRNIRTLPNNRILK 6062
Query 6503 NLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDL 6562
LGVD+ VIWDY + P + +T+ VC TDI + L VL+D R G
Sbjct 6063 GLGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEP-------NGLVVLYDDRY-GDYQS 6114
Query 6563 FRNARNGVLITEGSVKGLTPSKGPAQASV-NGVTLIGESVKTQFNYFKKVDGIIQQLPET 6621
F A N VL++ K + + P+ V NG+ L + +K+V+G LP T
Sbjct 6115 FLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---NLYVYKRVNGAFVTLPNT 6171
Query 6622 YFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMI 6681
TQ R E F+PRS +E DFL ++ + F++RY + +HI+YG+ QLGGLH +I
Sbjct 6172 INTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHILYGEVDKPQLGGLHTVI 6230
Query 6682 GLAKRSQDSPLKLEDFIPMDST-VKNYFITDAQTGSSKCVCSVIDLLLDDFV----EIIK 6736
G+ + + + L + DS ++NYF+ + GS K VC+V+DLLLDDF+ I+K
Sbjct 6231 GMYRLLRANKLNAKSVTNSDSDVMQNYFVL-SDNGSYKQVCTVVDLLLDDFLELLRNILK 6289
Query 6737 SQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRML 6796
+ SKVV V+IDY I+FM W +DG ++T YP+LQ++ W G MP LYK+Q +
Sbjct 6290 EYGTN-KSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQSA--WTCGYNMPELYKVQNCV 6346
Query 6797 LEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPG 6856
+E C++ NYG +P GI+MNVAKYTQLCQYL+ T+ VP+NMRV+HFGAGSDKGVAPG
Sbjct 6347 MEPCNIPNYGVGITLPSGILMNVAKYTQLCQYLSKTTICVPHNMRVMHFGAGSDKGVAPG 6406
Query 6857 TAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY---DPRTKH 6913
+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC +T +K+DL+ISDMY D + KH
Sbjct 6407 STVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYNTEHKFDLVISDMYTDNDSKRKH 6466
Query 6914 VTK-ENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNV 6972
N+ + F YL F++ LALGGS AVK+TE SW+ LY + +WWT F T V
Sbjct 6467 EGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSWHEVLYDIAQDCAWWTMFCTAV 6526
Query 6973 NASSSEAFLIGANYLGKP-KEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRG 7031
NASSSEAFLIG NYLG K ++ G T+HANYIFWRN N +Q S+YS+FD++KF L+L+
Sbjct 6527 NASSSEAFLIGVNYLGASEKVKVSGKTLHANYIFWRNCNYLQTSAYSIFDVAKFDLRLKA 6586
Query 7032 TAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILV 7071
T V++LK Q D++++L++ G+L++R+ +SD V
Sbjct 6587 TPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6626
Score = 163 bits (413), Expect = 6e-38, Method: Composition-based stats.
Identities = 74/349 (21%), Positives = 131/349 (38%), Gaps = 46/349 (13%)
Query 879 AVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAEC 938
AV Q V D+L + G +D A L ++ + + +
Sbjct 872 AVKPLPQKVVDVLGDWGEAVD----AQEQLCQQEPLQHTFEEPVENSTGSSKTMTEQVVV 927
Query 939 EEEEIDE-------------TCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDT 985
E++E+ E T ++ L F E V +++ + +
Sbjct 928 EDQELPVVEQDQDVVVYTPTDLEVAKETAEEVDEFILIFAVPKEEVVSQKDGAQ-IKQEP 986
Query 986 TEQSEIEPEPE--------PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVN 1037
+ + + E + T E+P +F Y ++ + I K IVN
Sbjct 987 IQVVKPQREKKAKKFKVKPATCEKP--KFLEYKTCVGDLTVV---IAKALDEFKEFCIVN 1041
Query 1038 AANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCL-HVV 1096
AAN H+ HG GVA A+ + +DY+K +GP + +C+ +VV
Sbjct 1042 AANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ---RLVTPSFVKGIQCVNNVV 1098
Query 1097 GPNLNAGEDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIA 1154
GP + L AAY+N ++ + P+LS GIFG ++ + +R +
Sbjct 1099 GPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGVD----FKMSIDAMRE-AFEG 1153
Query 1155 VNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVD 1203
+ L + +++D KQ+ TED + +S+V KP D
Sbjct 1154 CTIRVLLFSLSQEHIDYFDVTC---KQKTIYLTEDG-VKYRSIVLKPGD 1198
Score = 41.2 bits (95), Expect = 0.62, Method: Composition-based stats.
Identities = 41/255 (16%), Positives = 87/255 (34%), Gaps = 28/255 (11%)
Query 635 LSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVT 694
+ V+F W+ + IV V + C + +D ++ + +
Sbjct 512 FTKVVDFCDKHWKGFCVQLKRAKLIVTETFCVLKGVAQHCFQLLLDAIHSLYK------S 565
Query 695 IAGAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSE 754
L ++ + G+++ G E + +++ ++ S D + +
Sbjct 566 FKKCALGRIHGD--LLFWKGGVHKIVQDGDEIWFDAIDSVDVEDLGVVQEKSIDFEVCDD 623
Query 755 EVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFR 814
+ +N ++ D N + KD+ Y L A N V +
Sbjct 624 VTLPENQPGHMVQIEDDGK------------NYMFFRFKKDENIYYTPMSQLGAINVVCK 671
Query 815 LKGGAPIKGVTFGEDTVWEV--QGYKNVRITFELD-ERVDKVLNEKCSV-YTVESGTEVT 870
G K VTFGE TV E+ ++++ E E + + + V++ V
Sbjct 672 AGG----KTVTFGETTVQEIPPPDVVPIKVSIECCGEPWNTIFKKAYKEPIEVDTDLTVE 727
Query 871 EFACVVAEAVVKTLQ 885
+ V+ E + L+
Sbjct 728 QLLSVIYEKMCDDLK 742
>sp|P0C6Y2|R1AB_IBVBC Replicase polyprotein 1ab OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=rep
PE=3 SV=1
Length=6629
Score = 6359 bits (16498), Expect = 0.0, Method: Composition-based stats.
Identities = 2348/5680 (41%), Positives = 3252/5680 (57%), Gaps = 376/5680 (7%)
Query 1541 EVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPS 1600
K ++ T D + ++ + G QFG Y V + E K +P+
Sbjct 1174 TCKQKTIYLTEDGVKYRSIVLKPGDSLG-QFGQVYAKNKIVFTA---DDVEDKEILYVPT 1229
Query 1601 DDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLAL 1660
D E Y+ LD Y+ L +KW ++W D NC++SS ++ L
Sbjct 1230 TDKSILE----YYGLDAQKYVIYLQTL--AQKWNVQYRDNFLILEWRDGNCWISSAIVLL 1283
Query 1661 QQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLES 1720
Q +++F L EA+ + GD +F A A VG+ D + +L +H + +
Sbjct 1284 QAAKIRFKG-FLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFSDANWLLANLAEHFDADY 1342
Query 1721 AKRVLNV-VCKHCGQKTTTLTGVEAVM-YMGTLSYDNLKTGVSIPCVCGRDATQYLVQQE 1778
L V +CG K+ L G+EA + + + + KT S CG + T +++
Sbjct 1343 TNAFLKKRVSCNCGIKSYELRGLEACIQPVRATNLLHFKTQYSNCPTCGANNTDEVIEAS 1402
Query 1779 SSFVMMSAP--PAEYKLQQGTFLCANEYTGNYQCGH-YTHITAKETLYRIDGAHLTKMSE 1835
++++ A PA + + + G+ GH YT D +
Sbjct 1403 LPYLLLFATDGPATVDCDEDA-VGTVVFVGSTNSGHCYTQAAG----QAFDNLAKDRKFG 1457
Query 1836 YKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQ 1895
K P Y ++ K ++ +
Sbjct 1458 KKSPYITAMYTRFAFKNETSLPVAKQSKGKSKSVKEDVSNL------------------A 1499
Query 1896 PLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSAS 1955
ASFDN D Q + L V PD ++ Y +
Sbjct 1500 TSSKASFDNL----------TDFEQW--YDSNIYESLKVQESPD--------NFDKYVSF 1539
Query 1956 FKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDN 2015
T + + P T +R + S + + F DT
Sbjct 1540 ------------------TTKEDSKLPLTLKVRGIKSVVDFRSKDGFIYKLTPDTD---- 1577
Query 2016 LACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
S+ P V++ + +K V GN ++ L
Sbjct 1578 --ENSKAPVYYPVLDAIS---------LKAIWVEGNANFVVGHPNY-YSKSLHIPTFWEN 1625
Query 2076 Y---------VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQA 2126
+ ++ + + L+ IA V S + +G+A
Sbjct 1626 AENFVKMGDKIGGVTMGLWRAEHLNKP---NLERIFNIAKKAIVGSSVVTTQCGKLIGKA 1682
Query 2127 AITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKL 2186
A ++ R + + + + F + + + K + +
Sbjct 1683 ATFIADKVGGGVVRNITDSIKGLCGITRG--HFERKMSPQF--------LKTLMFFLFYF 1732
Query 2187 CLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVREL 2246
+ + V S K + LL++ S + VL S C ++
Sbjct 1733 LKASVKSVVASYKTVLCKVVLATLLIVWFVYTSNPVMFTGIRVL-DFLFEGSLCGPYKDY 1791
Query 2247 YLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVL 2306
+S +V + +C F C +CL DSL Y +++ YK + G W
Sbjct 1792 GKDSFDV--LRYCADDFICRVCLHDKDSLHLYKHAYSVE---QVYKDAAS--GFIFNWNW 1844
Query 2307 AYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--------WLMWFIISIVQMAPVSAMV 2358
Y++F F V Y + + NS +L WF V +
Sbjct 1845 LYLVFLILFVKPVAGF---VIICYCVKYLVLNSTVLQTGVCFLDWF---------VQTVF 1892
Query 2359 RMYIFFASFYYIWKSYV-----HIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYV 2413
+ F + +Y W Y H + C TC +C + R+ R E + +V G K+ +V
Sbjct 1893 SHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHV 1952
Query 2414 YANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAV 2473
Y N G FCK HNW C NCD + +TF+S EVA +LS + KR + PT + ++VD +
Sbjct 1953 YTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKPTAYAYHVVDEACL 2012
Query 2474 KNGALHLYFD-KAGQKTYERHPLSHFVNLDNL-RANNTKGSLPINVIVFDGKSKCDESA- 2530
+ ++L + K + F D L +A K +L I DG C+ +
Sbjct 2013 VDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSA 2072
Query 2531 -----SKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEK 2585
+K+A++YY+Q +C+PIL+LDQAL + VS + D S+ SV
Sbjct 2073 HALEEAKNAAIYYAQYLCKPILILDQALYEQL-VVEPVSKSVIDKVCSILSSIISVD--- 2128
Query 2586 LKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGD 2645
TA G D +LS ++ ++ H+ D++ TGD
Sbjct 2129 ------TAALNYKAGTLRDALLSI-------------TKDEEAVDMAIFCHNHDVDYTGD 2169
Query 2646 SCNNFMLTY-NKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRK 2704
N + +Y +TPRD G I+ +A N +V + ++W + + LS+ K
Sbjct 2170 GFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAP--PVVWKFSELIKLSDSCLK 2227
Query 2705 QIRSAAKKNNIPFRLTCATTRQVVNVITTKISL--KGGKIVS---TCFKLMLKATLLCVL 2759
+ SA K+ + F +T + +QV+ T K+ + K G IVS CFK K L+ +
Sbjct 2228 YLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKCFKSYFKWLLIFYI 2287
Query 2760 AALVC---YIVMPVHTLSIHDGY----TNEIIGYKAIQDGVTRDIISTDDCFANKHAGFD 2812
C Y M V +H Y T + G+K I GV R+I+ D CF+NK FD
Sbjct 2288 LFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVPEDTCFSNKFVNFD 2347
Query 2813 AWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAING-DFLH---------FL 2862
A++ G Y N ++CP+V A+I + G + G+PG V ++G F+H ++
Sbjct 2348 AFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMFIHMTQTERKPWYI 2403
Query 2863 PRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD-TNLLEGSIS 2921
P F+ + YT +I F TS + +A C ++ A P YC++ N G++
Sbjct 2404 PTWFNRE-IVGYTQDSIITEGSFYTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALP 2461
Query 2922 YSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRW 2981
+ + P Y +G + P L + VV YCR CE + G C+S + +W
Sbjct 2462 FGSIIPHRVYFQPNGVRLIVPQQILH-TPYVVKFVSDSYCRGSVCEYTRPGYCVSLNPQW 2520
Query 2982 VLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYF 3041
VL N+ Y + GVFCG L+ ++ + V ++ + +I ++V
Sbjct 2521 VLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLATMFLILVVVVLIFAMV 2579
Query 3042 MKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLA 3101
+KF+ VF Y V L+++++ ILC+ S L + V Y Y + + + +
Sbjct 2580 IKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLYCYASLVTSRNTVIIM 2639
Query 3102 HLQWFAMFSPIVPFWITAIYVFCISLKH---CHWFFNNYLRKRVMFNGVTF-STFEEAAL 3157
H F IVP W+ Y+ I + W + R +++G F ++ AA
Sbjct 2640 HCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKLYDGNEFVGNYDLAAK 2699
Query 3158 CTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALND 3217
TF++ ++KL +E ++ YL+ Y + KY+SG Y +A LA AL+
Sbjct 2700 STFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQ 2756
Query 3218 FSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVY 3277
+ NSG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+ LNGLWL DT+Y
Sbjct 2757 YRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIY 2816
Query 3278 CPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAG-NVQLRVIGHSMQNCLLRLKVDTSNP 3336
CPRHV+ + D+L +NH F V V L V+ ++ +L L+ +N
Sbjct 2817 CPRHVL---GKFSGDQWNDVLNLANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANA 2873
Query 3337 KTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDC 3396
+TPKYKF++ G +F++ Y G+ G+Y MR N TI+ SFL G+CGSVGFNI+
Sbjct 2874 ETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGV 2933
Query 3397 VSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGD 3456
V+F YMHH+ELP +H GTDL G+FYG +VD + AQ D +T N++AWLYAA+I+
Sbjct 2934 VNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVK 2993
Query 3457 RW------FLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
+L T +++D+N A + P + + LSA TG+ V + +
Sbjct 2994 ESSFSLPKWLESTTVSVDDYNKWAGDNGFTPFSTST--AITKLSAITGVDVCKLLRTIM- 3050
Query 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWM-----LLTFL 3565
+ + G ILG EDE TP V Q GV Q F V+ W L FL
Sbjct 3051 VKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSF---VRKATSWFWSRCVLACFL 3107
Query 3566 TSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLAT-- 3623
L +V T L F+VY L +MA+ + VKH A++ FLLP+L T
Sbjct 3108 FVLCAIVLFTAVPLKFYVYAAVIL-----LMAVLFIS-FTVKHVMAYMDTFLLPTLITVI 3161
Query 3624 ------------------VAYFNMVYMPASWVMRIMTWLELADTSLSGYR-LKDCVMYAS 3664
V + + Y P + ++ W+ L + ++ ++ C M +
Sbjct 3162 IGVCAEVPFIYNTLISQVVIFLSQWYDPVVF-DTMVPWMFLPLVLYTAFKCVQGCYMNSF 3220
Query 3665 ALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGV 3724
LL+L + ++T N +T + GN W L +
Sbjct 3221 NTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN--------WELFFELVHTTVLA 3265
Query 3725 VTTIMFLARAIVFVCVE----YYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
+ L VF C + Y ++ L +M+ +G+ C CYFGL+ +N+
Sbjct 3266 NVSSNSLIGLFVFKCAKWMLYYCNATYLNNYVLMAVMV--NCIGWLCTCYFGLYWWVNKV 3323
Query 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
F LTLG Y++ VS ++RYM + PPK+ + F NI + GIGG + +ATVQ+K+S
Sbjct 3324 FGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLPIATVQAKLS 3383
Query 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
DVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E + ++ +L L +
Sbjct 3384 DVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGECMDNLLGMLITLFCIDS 3443
Query 3901 AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYE----QAVANGDSEVVLKK 3956
+D++ C+++L LQ++ EFS +PSYA Y A+ YE + G ++ L
Sbjct 3444 TIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAA 3503
Query 3957 LKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRK 4016
+K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K
Sbjct 3504 YRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKK 3563
Query 4017 LDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQ 4076
+D++ LN + + A G VPL +P+ + KL +V+PD T+ +G TY++ +W I
Sbjct 3564 IDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNID 3623
Query 4077 QVVDADSKIVQLSEINMD-----NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQ 4128
V+DAD + + + N+AWPL V R V LQNNEL P ++
Sbjct 3624 TVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNKVDVVLQNNELMPHGVKT 3683
Query 4129 MSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEP 4188
+C AG Q C+ ++ YY N G V A+ S + +LK A F G IY +L+P
Sbjct 3684 KACVAGVDQAHCSVES-KCYYTNISGNSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDP 3741
Query 4189 PCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFC 4247
PC+F +V YLYFIK ++ RGMVLG+++ V LQ+ G+ TE +LS C
Sbjct 3742 PCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLC 3801
Query 4248 AFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYC 4307
+FAVDPA Y Y+A+G QP+ NCVKML H G+G AIT P DQ+S+GGAS CLYC
Sbjct 3802 SFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYC 3861
Query 4308 RCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQL 4363
R HI HP N G C KG +VQIPTT DPVGF LRN VCTVC W GYGC CD L
Sbjct 3862 RAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSL 3920
Query 4364 REPLMQSAD-------ASTFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNEKVAGFAK 4416
R+P +LNRV G S ARL P +G DVV RAFD+ N++ AG +
Sbjct 3921 RQPKSSVQSVAGASDFDKNYLNRVRGSSEARLIPLASGCDPDVVKRAFDVCNKESAGMFQ 3980
Query 4417 FLKTNCCRFQE----KDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCPAVAVHDFFK 4472
LK NC RFQE +D LDSYFVVK+ T SNY+HE++ Y +K A HDFF
Sbjct 3981 NLKRNCARFQELRDTEDGNLEYLDSYFVVKQTTPSNYEHEKSCYEDLKS-EVTADHDFFV 4039
Query 4473 FRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDD---DYF-NK 4528
F + + +ISRQRLTKYTM D YALRHFD +C+ LKEILVTY C +D +F
Sbjct 4040 FNKN---IYNISRQRLTKYTMMDFCYALRHFDPKDCEVLKEILVTYGCIEDYHPKWFEEN 4096
Query 4529 KDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNGNWYDF 4588
KDWYD +EN + A +G VR++LL ++F + M + G VGV+TLDNQDLNG +YDF
Sbjct 4097 KDWYDPIENSKYYVMLAKMGPIVRRALLNAIEFGNLMVEKGYVGVITLDNQDLNGKFYDF 4156
Query 4589 GDFVQVAPGCGVPIVDSYYSLLMPILTLTRALAAESHMDADLAKPLIKWDLLKYDFTEER 4648
GDF + APG GVP+ D+YYS +MPI+ +T ALA E + + D+ K +DLLKYD+TEE+
Sbjct 4157 GDFQKTAPGAGVPVFDTYYSYMMPIIAMTDALAPERYFEYDVHKGYKSYDLLKYDYTEEK 4216
Query 4649 LCLFDRYFKYWDQTYHPNCINCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVP 4708
LF +YFKYWDQ YHPNC +C DDRC++HCANFN+LFST+ P TSFG L RK+FVDGVP
Sbjct 4217 QELFQKYFKYWDQEYHPNCRDCSDDRCLIHCANFNILFSTLIPQTSFGNLCRKVFVDGVP 4276
Query 4709 FVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVA 4768
F+ + GYH +ELGV+ NQD + S++ +L+ + DPA+ + N L+D RT+CFSV
Sbjct 4277 FIATCGYHSKELGVIMNQDNTMSFSKMGLSQLMQFVGDPALLVGTSNNLVDLRTSCFSVC 4336
Query 4769 ALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYN 4828
ALT+ + QTVKPG+FNKDFYDFA G FKEGSS+ LKHFF+ Q GNAAI+DYDYYRYN
Sbjct 4337 ALTSGITHQTVKPGHFNKDFYDFAEKAGMFKEGSSIPLKHFFYPQTGNAAINDYDYYRYN 4396
Query 4829 LPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSM 4888
PTM DI QLLF +EV KYF+CY+GGCI A+QV+VNNLDKSAG+PFNK+GKARLYY+ M
Sbjct 4397 RPTMFDICQLLFCLEVTSKYFECYEGGCIPASQVVVNNLDKSAGYPFNKFGKARLYYE-M 4455
Query 4889 SYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSI 4948
S E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI STMTNRQFHQK+LKSI
Sbjct 4456 SLEEQDQLFEITKKNVLPTITQMNLKYAISAKNRARTVAGVSILSTMTNRQFHQKILKSI 4515
Query 4949 AATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLA 5008
TR A+VVIGT+KFYGGW NML+ + VE P LMGWDYPKCDRAMPN+LRI ASLVLA
Sbjct 4516 VNTRNASVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKCDRAMPNLLRIAASLVLA 4575
Query 5009 RKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQA 5068
RKH CC+ S R YRL NECAQVLSE V+ G +YVKPGGTSSGDATTAYANSVFNI QA
Sbjct 4576 RKHTNCCSWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSSGDATTAYANSVFNIIQA 4635
Query 5069 VTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILS 5128
+ANV LLS I +++LQ+ LY+ +YR + D FV++FY+YL K+FS+MILS
Sbjct 4636 TSANVARLLSVITRDIVYDNIKSLQYELYQQVYRRVNFDPAFVEKFYSYLCKNFSLMILS 4695
Query 5129 DDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTML 5188
DD VVCYN+ A QGLVA I F+ VLYYQNNVFM+++KCW E DL KGPHEFCSQHTML
Sbjct 4696 DDGVVCYNNTLAKQGLVADISGFREVLYYQNNVFMADSKCWVEPDLEKGPHEFCSQHTML 4755
Query 5189 VKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYAD 5248
V+ + YLPYPDPSRILGA FVDD+ KT+ ++ER+++LAIDAYPL H N+EY
Sbjct 4756 VEVDGEPKYLPYPDPSRILGACVFVDDVDKTEPVAVMERYIALAIDAYPLVHHENEEYKK 4815
Query 5249 VFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVL 5308
VF + L YIRKL+ EL+ +ML YS ++ D S++WE EFYE MY T LQ+ G CV+
Sbjct 4816 VFFVLLAYIRKLYQELSQNMLMDYSFVMDIDKGSKFWEQEFYENMYRAPTTLQSCGVCVV 4875
Query 5309 CNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGG 5368
CNSQT LRCG CIR+PFLCCKCCYDHV+ T HK VLS+NPY+C+ GC DVT+LYLGG
Sbjct 4876 CNSQTILRCGNCIRKPFLCCKCCYDHVMHTDHKNVLSINPYICSQLGCGEADVTKLYLGG 4935
Query 5369 MSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCT 5428
MSY+C +HKP +S PL +NG VFG+Y+ C GS+NV DFN +AT +W+ YILAN C+
Sbjct 4936 MSYFCGNHKPKLSIPLVSNGTVFGIYRANCAGSENVDDFNQLATTNWSIVEPYILANRCS 4995
Query 5429 ERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRV 5488
+ L+ FAAET+KATEE K + A VREV SDREL LSWE GK RPPLNRNYVFTGY
Sbjct 4996 DSLRRFAAETVKATEELHKQQFASAEVREVFSDRELILSWEPGKTRPPLNRNYVFTGYHF 5055
Query 5489 TKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYV 5548
T+ SKVQ+G++TFEKG+ D V Y+ T+T KL+VGD FVLTSH V+ L APTL PQ+ +
Sbjct 5056 TRTSKVQLGDFTFEKGEGKDVVYYKATSTAKLSVGDIFVLTSHNVVSLVAPTLCPQQTFS 5115
Query 5549 RITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYT 5608
R L P + + + F +N+ Y VG QK +T+QGPPG+GKSHFAIGLA+Y+ SAR+V+T
Sbjct 5116 RFVNLRPNVMVPECFVNNIPLYHLVGKQKRTTVQGPPGSGKSHFAIGLAVYFSSARVVFT 5175
Query 5609 ACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETT 5668
ACSHAAVDALCEKA K+L +D C+RI+P R V+CF KFK N T ++Y+F T+NALPE +
Sbjct 5176 ACSHAAVDALCEKAFKFLKVDDCTRIVPQRTTVDCFSKFKANDTGKKYIFSTINALPEVS 5235
Query 5669 ADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCR 5728
DI++ DE+SM TNY+LS +N ++ ++ VY+GDPAQLPAPRTLL G+L P+ +N V
Sbjct 5236 CDILLVDEVSMLTNYELSFINGKINYQYVVYVGDPAQLPAPRTLLN-GSLSPKDYNVVTN 5294
Query 5729 LMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKG---VITHDV 5785
LM + PD+FL C RCP EIVDTVS LVYD K A+ +S +CFK+ + H+
Sbjct 5295 LMVCVKPDIFLAKCYRCPKEIVDTVSTLVYDGKFIANNPESRECFKVIVNNGNSDVGHES 5354
Query 5786 SSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYV 5845
SA N Q+ V++F+ RN WR+A+FISPYN+ N A ++LGL QTVDSSQGSEYDYV
Sbjct 5355 GSAYNTTQLEFVKDFVCRNKQWREAIFISPYNAMNQRAYRMLGLNVQTVDSSQGSEYDYV 5414
Query 5846 IFTQTTETAHSCNVNRFNVAITRAKIGILCIMSDRD-LYDKLQFTSLEIPRRNVATLQAE 5904
IF T ++ H+ N+NRFNVA+TRAK GIL +M RD LY L+FT L+ + +LQ
Sbjct 5415 IFCVTADSQHALNINRFNVALTRAKRGILVVMRQRDELYSALKFTELD----SETSLQG- 5469
Query 5905 NVTGLFKDCSKIITGLHPTQAPTHLSVDIKFKTEGLCVDIPGIP--KDMTYRRLISMMGF 5962
TGLFK C+K +G+HP A T ++ +K + + ++TY+ LIS++GF
Sbjct 5470 --TGLFKICNKEFSGVHPAYAVTTKALAATYKVNDELAALVNVEAGSEITYKHLISLLGF 5527
Query 5963 KMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATRDAVGTNLPLQLGFSTGVNLVAV 6022
KM+ V G NMFITR+EAIR+VR W+GFDVE HA +GTNLP Q+GFSTG + V
Sbjct 5528 KMSVNVEGCHNMFITRDEAIRNVRGWVGFDVEATHACGTNIGTNLPFQVGFSTGADFVVT 5587
Query 6023 PTGYVDTENNTEFTRVNAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKGLSDR 6082
P G VDT F VN+K PPG+QF HL L PW+V+R +IVQML+D L +SD
Sbjct 5588 PEGLVDTSIGNNFEPVNSKAPPGEQFNHLRVLFKSAKPWHVIRPRIVQMLADNLCNVSDC 5647
Query 6083 VVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGFDYVYNPF 6142
VVFV W HG ELT+++YFVKIG E+ C C RAT F++ + YACW H +GFD+VYNP
Sbjct 5648 VVFVTWCHGLELTTLRYFVKIGKEQVCS-CGSRATTFNSHTQAYACWKHCLGFDFVYNPL 5706
Query 6143 MIDVQQWGFTGNLQSNHDQHCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWSVEYPIIG 6202
++D+QQWG++GNLQ NHD HC VHG+AHVAS DAIMTRCLA++ F + V+W + YP I
Sbjct 5707 LVDIQQWGYSGNLQFNHDLHCNVHGHAHVASVDAIMTRCLAINNAFCQDVNWDLTYPHIA 5766
Query 6203 DELRVNSACRKVQHMVVKSALLADKFPVLHDIGNPKAIKCVPQAEVEWKFYDAQPCSDKA 6262
+E VNS+CR +Q M + + + A K V++DIGNPK IKCV + +V ++FYD P
Sbjct 5767 NEDEVNSSCRYLQRMYLNACVDALKVNVVYDIGNPKGIKCVRRGDVNFRFYDKNPIVRNV 5826
Query 6263 YKIEELFYSYATHHDKFTDGVCLFWNCNVDRYPANAIVCRFDTRVLSNLNLPGCDGGSLY 6322
+ E Y Y H DKF DG+C+FWNCNVD YP N++VCR+DTR LS NLPGC+GGSLY
Sbjct 5827 KQFE---YDYNQHKDKFADGLCMFWNCNVDCYPDNSLVCRYDTRNLSVFNLPGCNGGSLY 5883
Query 6323 VNKHAFHTPAFDKSAFTNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLG 6382
VNKHAF+TP FD+ +F NLK +PFF+Y SPCE+ V+ D V L + CIT+CN+G
Sbjct 5884 VNKHAFYTPKFDRISFRNLKAMPFFFYDSSPCETIQVDGVAQ-DLVSLATKDCITKCNIG 5942
Query 6383 GAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTRLQSLENVAYNVVNKG 6442
GAVC+ HA Y +++ +YN ++AGF+ W+ + + YNLW +F+ LQS++N+AYN+ G
Sbjct 5943 GAVCKKHAQMYAEFVTSYNAAVTAGFTFWVTNKLNPYNLWKSFSALQSIDNIAYNMYKGG 6002
Query 6443 HFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELWAKRNIKPVPEIKILN 6502
H+D AGE P I + V+ G++ +F N+TTLP +VAFEL+AKRNI+ +P +IL
Sbjct 6003 HYDAIAGEMPTVITGDKVFVIDQGVEKAVFVNQTTLPTSVAFELYAKRNIRTLPNNRILK 6062
Query 6503 NLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSSLTVLFDGRVEGQVDL 6562
LGVD+ VIWDY + P + +T+ VC TDI + L VL+D R G
Sbjct 6063 GLGVDVTNGFVIWDYANQTPLYRNTVKVCAYTDIEP-------NGLVVLYDDRY-GDYQS 6114
Query 6563 FRNARNGVLITEGSVKGLTPSKGPAQASV-NGVTLIGESVKTQFNYFKKVDGIIQQLPET 6621
F A N VL++ K + + P+ V NG+ L + +K+V+G LP T
Sbjct 6115 FLAADNAVLVSTQCYKRYSYVEIPSNLLVQNGMPLKDGA---NLYVYKRVNGAFVTLPNT 6171
Query 6622 YFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMI 6681
TQ R E F+PRS +E DFL ++ + F++RY + +HI+YG+ QLGGLH +I
Sbjct 6172 INTQGRSYETFEPRSDIERDFLAMSEESFVERYG-KDLGLQHILYGEVDKPQLGGLHTVI 6230
Query 6682 GLAKRSQDSPLKLEDFIPMDST-VKNYFITDAQTGSSKCVCSVIDLLLDDFV----EIIK 6736
G+ + + + L + DS ++NYF+ + GS K VC+V+DLLLDDF+ I+K
Sbjct 6231 GMYRLLRANKLNAKSVTNSDSDVMQNYFVL-SDNGSYKQVCTVVDLLLDDFLELLRNILK 6289
Query 6737 SQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKMQRML 6796
+ SKVV V+IDY I+FM W +DG ++T YP+LQ++ W G MP LYK+Q +
Sbjct 6290 EYGTN-KSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQSA--WTCGYNMPELYKVQNCV 6346
Query 6797 LEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPG 6856
+E C++ NYG +P GI+MNVAKYTQLCQYL T+ VP+NMRV+HFGAGSDKGVAPG
Sbjct 6347 MEPCNIPNYGVGITLPSGILMNVAKYTQLCQYLLKTTICVPHNMRVMHFGAGSDKGVAPG 6406
Query 6857 TAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY---DPRTKH 6913
+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC +T +K+DL+ISDMY D + KH
Sbjct 6407 STVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYNTEHKFDLVISDMYTDNDSKRKH 6466
Query 6914 VTK-ENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAFVTNV 6972
N+ + F YL F++ LALGGS AVK+TE SW+ LY + +WWT F T V
Sbjct 6467 EGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSWHEVLYDIAQDCAWWTMFCTAV 6526
Query 6973 NASSSEAFLIGANYLGKP-KEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRG 7031
NASSSEAFLIG NYLG K ++ G T+HANYIFWRN N +Q S+YS+FD++KF L+L+
Sbjct 6527 NASSSEAFLIGVNYLGASEKVKVSGKTLHANYIFWRNCNYLQTSAYSIFDVAKFDLRLKA 6586
Query 7032 TAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILV 7071
T V++LK Q D++++L++ G+L++R+ +SD V
Sbjct 6587 TPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 6626
Score = 163 bits (413), Expect = 6e-38, Method: Composition-based stats.
Identities = 74/349 (21%), Positives = 131/349 (38%), Gaps = 46/349 (13%)
Query 879 AVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAEC 938
AV Q V D+L + G +D A L ++ + + +
Sbjct 872 AVKPLPQKVVDVLGDWGEAVD----AQEQLCQQEPLQHTFEEPVENSTGSSKTMTEQVVV 927
Query 939 EEEEIDE-------------TCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDT 985
E++E+ E T ++ L F E V +++ + +
Sbjct 928 EDQELPVVEQDQDVVVYTPTDLEVAKETAEEVDEFILIFAVPKEEVVSQKDGAQ-IKQEP 986
Query 986 TEQSEIEPEPE--------PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVN 1037
+ + + E + T E+P +F Y ++ + I K IVN
Sbjct 987 IQVVKPQREKKAKKFKVKPATCEKP--KFLEYKTCVGDLTVV---IAKALDEFKEFCIVN 1041
Query 1038 AANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCL-HVV 1096
AAN H+ HG GVA A+ + +DY+K +GP + +C+ +VV
Sbjct 1042 AANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ---RLVTPSFVKGIQCVNNVV 1098
Query 1097 GPNLNAGEDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIA 1154
GP + L AAY+N ++ + P+LS GIFG ++ + +R +
Sbjct 1099 GPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGVD----FKMSIDAMRE-AFEG 1153
Query 1155 VNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVD 1203
+ L + +++D KQ+ TED + +S+V KP D
Sbjct 1154 CTIRVLLFSLSQEHIDYFDVTC---KQKTIYLTEDG-VKYRSIVLKPGD 1198
Score = 41.2 bits (95), Expect = 0.62, Method: Composition-based stats.
Identities = 41/255 (16%), Positives = 87/255 (34%), Gaps = 28/255 (11%)
Query 635 LSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVT 694
+ V+F W+ + IV V + C + +D ++ + +
Sbjct 512 FTKVVDFCDKHWKGFCVQLKRAKLIVTETFCVLKGVAQHCFQLLLDAIHSLYK------S 565
Query 695 IAGAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSE 754
L ++ + G+++ G E + +++ ++ S D + +
Sbjct 566 FKKCALGRIHGD--LLFWKGGVHKIVQDGDEIWFDAIDSVDVEDLGVVQEKSIDFEVCDD 623
Query 755 EVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFR 814
+ +N ++ D N + KD+ Y L A N V +
Sbjct 624 VTLPENQPGHMVQIEDDGK------------NYMFFRFKKDENIYYTPMSQLGAINVVCK 671
Query 815 LKGGAPIKGVTFGEDTVWEV--QGYKNVRITFELD-ERVDKVLNEKCSV-YTVESGTEVT 870
G K VTFGE TV E+ ++++ E E + + + V++ V
Sbjct 672 AGG----KTVTFGETTVQEIPPPDVVPIKVSIECCGEPWNTIFKKAYKEPIEVDTDLTVE 727
Query 871 EFACVVAEAVVKTLQ 885
+ V+ E + L+
Sbjct 728 QLLSVIYEKMCDDLK 742
>sp|P0C6U8|R1A_SARS Replicase polyprotein 1a OS=Severe acute respiratory
syndrome coronavirus OX=694009 GN=1a PE=1 SV=1
Length=4382
Score = 6306 bits (16359), Expect = 0.0, Method: Composition-based stats.
Identities = 4378/4378 (100%), Positives = 4378/4378 (100%), Gaps = 0/4378 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW
Sbjct 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL
Sbjct 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY
Sbjct 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV
Sbjct 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC
Sbjct 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV
Sbjct 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL
Sbjct 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
Query 961 PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC 1020
PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC
Sbjct 961 PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC 1020
Query 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS
Sbjct 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
Query 1081 CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL 1140
CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL
Sbjct 1081 CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL 1140
Query 1141 QVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK 1200
QVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK
Sbjct 1141 QVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQK 1200
Query 1201 PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP 1260
PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP
Sbjct 1201 PVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAP 1260
Query 1261 YMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKT 1320
YMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKT
Sbjct 1261 YMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKT 1320
Query 1321 ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQR 1380
ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQR
Sbjct 1321 ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQR 1380
Query 1381 KYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAAR 1440
KYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAAR
Sbjct 1381 KYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAAR 1440
Query 1441 CMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG 1500
CMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG
Sbjct 1441 CMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELG 1500
Query 1501 VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQL 1560
VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQL
Sbjct 1501 VEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQL 1560
Query 1561 VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFL 1620
VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFL
Sbjct 1561 VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFL 1620
Query 1621 GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR 1680
GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR
Sbjct 1621 GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR 1680
Query 1681 AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT 1740
AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT
Sbjct 1681 AGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLT 1740
Query 1741 GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC 1800
GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC
Sbjct 1741 GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC 1800
Query 1801 ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYK 1860
ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYK
Sbjct 1801 ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYK 1860
Query 1861 LDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQ 1920
LDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQ
Sbjct 1861 LDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLNQ 1920
Query 1921 MTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF 1980
MTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF
Sbjct 1921 MTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF 1980
Query 1981 KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE 2040
KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE
Sbjct 1981 KPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIE 2040
Query 2041 CDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA 2100
CDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA
Sbjct 2041 CDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIA 2100
Query 2101 THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFT 2160
THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFT
Sbjct 2101 THGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFT 2160
Query 2161 KSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSL 2220
KSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSL
Sbjct 2161 KSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSL 2220
Query 2221 ICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPA 2280
ICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPA
Sbjct 2221 ICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPA 2280
Query 2281 LETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW 2340
LETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW
Sbjct 2281 LETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW 2340
Query 2341 LMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC 2400
LMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC
Sbjct 2341 LMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVEC 2400
Query 2401 TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINP 2460
TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINP
Sbjct 2401 TTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINP 2460
Query 2461 TDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVF 2520
TDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVF
Sbjct 2461 TDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVF 2520
Query 2521 DGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFS 2580
DGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFS
Sbjct 2521 DGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFS 2580
Query 2581 VPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDL 2640
VPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDL
Sbjct 2581 VPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDL 2640
Query 2641 EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE 2700
EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE
Sbjct 2641 EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSE 2700
Query 2701 QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLA 2760
QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLA
Sbjct 2701 QLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLA 2760
Query 2761 ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG 2820
ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG
Sbjct 2761 ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG 2820
Query 2821 SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLI 2880
SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLI
Sbjct 2821 SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLI 2880
Query 2881 EYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQ 2940
EYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQ
Sbjct 2881 EYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQ 2940
Query 2941 FPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA 3000
FPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA
Sbjct 2941 FPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDA 3000
Query 3001 MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANAL 3060
MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANAL
Sbjct 3001 MNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANAL 3060
Query 3061 LFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAI 3120
LFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAI
Sbjct 3061 LFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAI 3120
Query 3121 YVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ 3180
YVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ
Sbjct 3121 YVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQ 3180
Query 3181 YNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQ 3240
YNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQ
Sbjct 3181 YNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQ 3240
Query 3241 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3300
SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR
Sbjct 3241 SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIR 3300
Query 3301 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG
Sbjct 3301 KSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
Query 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK
Sbjct 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
Query 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
Sbjct 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
Query 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC
Sbjct 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
Query 3541 SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA 3600
SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA
Sbjct 3541 SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA 3600
Query 3601 CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCV 3660
CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCV
Sbjct 3601 CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCV 3660
Query 3661 MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN 3720
MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN
Sbjct 3661 MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN 3720
Query 3721 YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY
Sbjct 3721 YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
Query 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS
Sbjct 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
Query 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG
Sbjct 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
Query 3901 AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKS 3960
AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKS
Sbjct 3901 AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKS 3960
Query 3961 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4020
LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND
Sbjct 3961 LNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDND 4020
Query 4021 ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD 4080
ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD
Sbjct 4021 ALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVD 4080
Query 4081 ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTAC 4140
ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTAC
Sbjct 4081 ADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTAC 4140
Query 4141 TDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP 4200
TDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP
Sbjct 4141 TDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGP 4200
Query 4201 KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDY 4260
KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDY
Sbjct 4201 KVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDY 4260
Query 4261 LASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFC 4320
LASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFC
Sbjct 4261 LASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFC 4320
Query 4321 DLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
DLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN
Sbjct 4321 DLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
>sp|P0C6T7|R1A_BCRP3 Replicase polyprotein 1a OS=Bat coronavirus
Rp3/2004 OX=349344 GN=1a PE=3 SV=1
Length=4380
Score = 6272 bits (16271), Expect = 0.0, Method: Composition-based stats.
Identities = 4228/4379 (97%), Positives = 4298/4379 (98%), Gaps = 4/4379 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLVLG+NEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLK+GTCG+VELEKGV
Sbjct 1 MESLVLGINEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKSGTCGIVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQ EQPYVFIKRSDA T+HGH+V ELVAE+DG+QYGRSGITLGVLVPHVGETPIAYRN
Sbjct 61 LPQPEQPYVFIKRSDAQGTDHGHRVRELVAELDGVQYGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHS+GIDLKSYDLGDELGTDPIEDYEQNWNTKHGSG LRELTRELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGVLRELTRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
A+TRYVDNNFCGPDGYPL+CIKD LARAGKSMCTLSEQLDYIESKRGVYCCRDH HEIAW
Sbjct 181 ALTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCRDHGHEIAW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVA+PQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCE CGTENLV EGP TCGYL
Sbjct 301 RSVYPVATPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVSEGPNTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
PTNAVVKMPCPACQDPEIGPEHS ADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR
Sbjct 361 PTNAVVKMPCPACQDPEIGPEHSAADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDF LNEEVAIILASF
Sbjct 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFQLNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKP+KGAWNIGQ RSVLTPLCGFPSQA
Sbjct 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPIKGAWNIGQHRSVLTPLCGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIF+RTLDAANHSIPDLQRAAVTILD ISEQSLRLVDAMVYTS+LLTNSVIIMAY
Sbjct 541 AGVIRSIFSRTLDAANHSIPDLQRAAVTILDSISEQSLRLVDAMVYTSNLLTNSVIIMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQTSQWLSNLL TTVEKLRPIF WIEAKLSAGVEFLKDAWEILKFLITGVFDIV
Sbjct 601 VTGGLVQQTSQWLSNLLDTTVEKLRPIFAWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVASDNIKDCVKCF+DVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC
Sbjct 661 KGQIQVASDNIKDCVKCFVDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGA+VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAVVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVC+NGLMLLEIK EQYCALSPGLLATNNVFRLKGGAP KGVTFGEDTV EVQGYKNV
Sbjct 781 TPVCINGLMLLEIKANEQYCALSPGLLATNNVFRLKGGAPTKGVTFGEDTVVEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
Sbjct 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDE-TCEHEYGTEDDYQG 959
WSVATFYLFDD+GEE SSRMYCSFYPPDEEE+ + EEEE+ E TCEHEYGTE+DY+G
Sbjct 901 WSVATFYLFDDSGEEKLSSRMYCSFYPPDEEEDCEEYEEEEEVSERTCEHEYGTEEDYKG 960
Query 960 LPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
LPLEFGAS + ++VEE+EEEDWLDD E EPEPEP EEPVNQ TGYLKLTDNVAIK
Sbjct 961 LPLEFGASTDIIQVEEQEEEDWLDD---AVEAEPEPEPLHEEPVNQLTGYLKLTDNVAIK 1017
Query 1020 CVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGG 1079
CVDIV+EAQ+ANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESD YIKLNGPLTVGG
Sbjct 1018 CVDIVEEAQNANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDHYIKLNGPLTVGG 1077
Query 1080 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1139
SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS
Sbjct 1078 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1137
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQ 1199
LQ+CVQTVRTQVYI VNDK LYEQVVMDYLD+LKP+VEAPKQE P E K +EKSVVQ
Sbjct 1138 LQMCVQTVRTQVYIVVNDKVLYEQVVMDYLDSLKPKVEAPKQEVLPKAEYPKVDEKSVVQ 1197
Query 1200 KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDA 1259
K +DVKPKIKACIDEVTTTLEETKFLTNKLLLF DINGKLY DS+NMLRGEDMSFLEKDA
Sbjct 1198 KTIDVKPKIKACIDEVTTTLEETKFLTNKLLLFTDINGKLYQDSKNMLRGEDMSFLEKDA 1257
Query 1260 PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAK 1319
PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVP++EYITTYPGQGCAGYTLEEAK
Sbjct 1258 PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPINEYITTYPGQGCAGYTLEEAK 1317
Query 1320 TALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQ 1379
TALKKCKSAFYVLPSE PNAKEEILGTVSWNLREMLAHAEETRKLMP+CMDVRAIMATIQ
Sbjct 1318 TALKKCKSAFYVLPSETPNAKEEILGTVSWNLREMLAHAEETRKLMPVCMDVRAIMATIQ 1377
Query 1380 RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA 1439
RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA
Sbjct 1378 RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA 1437
Query 1440 RCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTEL 1499
RCMRSLKAPA+VSVSSPDAVTTYNGYLTSSSKTSE+HFVETVSLAGSYRDWSYSGQRTEL
Sbjct 1438 RCMRSLKAPAIVSVSSPDAVTTYNGYLTSSSKTSEDHFVETVSLAGSYRDWSYSGQRTEL 1497
Query 1500 GVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQ 1559
GVEFLKRG+KIVYHTLESPV+FHLDGEVL LDKLKSLLSLREVKTIKVFTTVDNTNLHTQ
Sbjct 1498 GVEFLKRGEKIVYHTLESPVKFHLDGEVLPLDKLKSLLSLREVKTIKVFTTVDNTNLHTQ 1557
Query 1560 LVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF 1619
LVDMSMTYGQQ GPTYL+GADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF
Sbjct 1558 LVDMSMTYGQQLGPTYLEGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF 1617
Query 1620 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRA 1679
LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ+EVKFNAPALQEAYYRA
Sbjct 1618 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQIEVKFNAPALQEAYYRA 1677
Query 1680 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1739
RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL
Sbjct 1678 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1737
Query 1740 TGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL 1799
TGVEAVMYMGTLSYDNLK GVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL
Sbjct 1738 TGVEAVMYMGTLSYDNLKMGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL 1797
Query 1800 CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY 1859
CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY
Sbjct 1798 CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY 1857
Query 1860 KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLN 1919
KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL+PTQPLPNASFDNFKLTCSNTKFADDLN
Sbjct 1858 KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLIPTQPLPNASFDNFKLTCSNTKFADDLN 1917
Query 1920 QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT 1979
QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT
Sbjct 1918 QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT 1977
Query 1980 FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVI 2039
FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPT EEVVENPTIQKEVI
Sbjct 1978 FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTPEEVVENPTIQKEVI 2037
Query 2040 ECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTI 2099
ECDVKTTEVVGNVILKPSDEGVKVTQEL HEDLMAAYVENTSITIKKPNELSLALGLKTI
Sbjct 2038 ECDVKTTEVVGNVILKPSDEGVKVTQELDHEDLMAAYVENTSITIKKPNELSLALGLKTI 2097
Query 2100 ATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTF 2159
ATHGIAAINSVPW KILAYVKPFLGQAA+TTSNCAKRL QR+FNNYMPYV TLLFQLCTF
Sbjct 2098 ATHGIAAINSVPWGKILAYVKPFLGQAAVTTSNCAKRLVQRMFNNYMPYVLTLLFQLCTF 2157
Query 2160 TKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS 2219
TKSTNSRIRASLPTTIAKNSV+ + +LCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS
Sbjct 2158 TKSTNSRIRASLPTTIAKNSVRGIVRLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS 2217
Query 2220 LICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYP 2279
LI VTAA GVLLSNFGAPSYC+GVRE YLNSSNVTTMDFCEGSFPCS+CLSGLDSLDSYP
Sbjct 2218 LIYVTAALGVLLSNFGAPSYCSGVRESYLNSSNVTTMDFCEGSFPCSVCLSGLDSLDSYP 2277
Query 2280 ALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2339
ALETIQVTISSYKLDLTILGLAAEW AYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS
Sbjct 2278 ALETIQVTISSYKLDLTILGLAAEWFFAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2337
Query 2340 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2399
WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE
Sbjct 2338 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2397
Query 2400 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPIN 2459
CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFC GSTFISDEVARDLSLQFKRPIN
Sbjct 2398 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCAGSTFISDEVARDLSLQFKRPIN 2457
Query 2460 PTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2519
PTDQSSY+VDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV
Sbjct 2458 PTDQSSYVVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2517
Query 2520 FDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2579
FDGKSKCDESA+KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF
Sbjct 2518 FDGKSKCDESAAKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2577
Query 2580 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD 2639
SVPMEKLKALVATAHSELAKGVALDGVLSTFVSA+RQGVVDTDVDTKDVIECLKLSHHSD
Sbjct 2578 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSASRQGVVDTDVDTKDVIECLKLSHHSD 2637
Query 2640 LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLS 2699
LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVA+SHNVSLIWNVKDYMSLS
Sbjct 2638 LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVARSHNVSLIWNVKDYMSLS 2697
Query 2700 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVL 2759
EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVST FK+MLKATLLCVL
Sbjct 2698 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTWFKIMLKATLLCVL 2757
Query 2760 AALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRG 2819
AALVCYIVMPVH LS+H GYTNEIIGYKAIQDGVTRDI+STDDCFANKHAGFD+WFSQRG
Sbjct 2758 AALVCYIVMPVHILSVHGGYTNEIIGYKAIQDGVTRDIVSTDDCFANKHAGFDSWFSQRG 2817
Query 2820 GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL
Sbjct 2818 GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2877
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2939
IEYSDF+TSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII
Sbjct 2878 IEYSDFSTSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2937
Query 2940 QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVD 2999
QFPN YLEGSVRVVTTFDAEYCRHGTCERSE GICLSTSGRWVLNNEHYRAL GVFCGVD
Sbjct 2938 QFPNAYLEGSVRVVTTFDAEYCRHGTCERSEAGICLSTSGRWVLNNEHYRALPGVFCGVD 2997
Query 3000 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANA 3059
AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRR FGEYNHVVAANA
Sbjct 2998 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRAFGEYNHVVAANA 3057
Query 3060 LLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3119
LFLMSFTILCL PAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA
Sbjct 3058 PLFLMSFTILCLAPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3117
Query 3120 IYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3179
IYVFCISLKH HWFFNNYLRKRV+FNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT
Sbjct 3118 IYVFCISLKHFHWFFNNYLRKRVVFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3177
Query 3180 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3239
QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL
Sbjct 3178 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3237
Query 3240 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI 3299
QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI
Sbjct 3238 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI 3297
Query 3300 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3359
RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN
Sbjct 3298 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3357
Query 3360 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3419
GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT VHAGTDLEG
Sbjct 3358 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTEVHAGTDLEG 3417
Query 3420 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3479
KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY
Sbjct 3418 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3477
Query 3480 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3539
EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ
Sbjct 3478 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3537
Query 3540 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIA 3599
CSGVTFQGKFK+IVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA+A
Sbjct 3538 CSGVTFQGKFKRIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAVA 3597
Query 3600 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3659
ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC
Sbjct 3598 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3657
Query 3660 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3719
VMYASALVLL+LMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS
Sbjct 3658 VMYASALVLLVLMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3717
Query 3720 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3779
NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR
Sbjct 3718 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3777
Query 3780 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3839
YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM
Sbjct 3778 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3837
Query 3840 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3899
SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ
Sbjct 3838 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3897
Query 3900 GAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3959
GAVDIN+LCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK
Sbjct 3898 GAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3957
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
SLNVAKSEFDR+AAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN
Sbjct 3958 SLNVAKSEFDRNAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4017
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV
Sbjct 4018 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4077
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4139
DADSKIVQLSEINM+NS NLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA
Sbjct 4078 DADSKIVQLSEINMENSSNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4137
Query 4140 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4199
CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG
Sbjct 4138 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4197
Query 4200 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4259
PKVKYL+FIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD
Sbjct 4198 PKVKYLHFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4257
Query 4260 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4319
YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF
Sbjct 4258 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4317
Query 4320 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP+MQSADASTFLN
Sbjct 4318 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPMMQSADASTFLN 4376
>sp|P0C6F8|R1A_BCHK3 Replicase polyprotein 1a OS=Bat coronavirus
HKU3 OX=442736 GN=1a PE=3 SV=1
Length=4376
Score = 6191 bits (16062), Expect = 0.0, Method: Composition-based stats.
Identities = 4110/4379 (94%), Positives = 4250/4379 (97%), Gaps = 8/4379 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV
Sbjct 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDALSTNHGHKVVELVAE+DGIQ+GRSGITLGVLVPHVGETPIAYRN
Sbjct 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAELDGIQFGRSGITLGVLVPHVGETPIAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHS+GIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG
Sbjct 121 VLLRKNGNKGAGGHSFGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
VTRYVDNNFCGPDGYPL+CIKDFLARAGKSMCTLSEQLDYIESKRGVYCCR+HEHEI W
Sbjct 181 VVTRYVDNNFCGPDGYPLECIKDFLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERS+KSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSEKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVA+PQECN+MHLSTLMKCNHCDEVSWQTCDFLKATCE CGTENLV EGPTTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
PTNAVVKMPCPACQDPE+GPEHSVADYHNHSNIETRLRKGGRT+CFGGCVF+YVGCYNKR
Sbjct 361 PTNAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFSYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASA+IG+ HTGITG+NVETLNEDLLEIL+RERVNINIVGDF NEEVAIILASF
Sbjct 421 AYWVPRASANIGANHTGITGENVETLNEDLLEILNRERVNINIVGDFRFNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SAS SAFI+T+K LDYKSFK IVESCGNYKVT GKPV GAWNIGQQRS+LTPLCGFPSQA
Sbjct 481 SASPSAFIETVKGLDYKSFKVIVESCGNYKVTNGKPVTGAWNIGQQRSILTPLCGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIF+RTLDAANHSI DLQRAAVT LDGISEQSLRLVDAMVYTSDLLTNSV++MAY
Sbjct 541 AGVIRSIFSRTLDAANHSILDLQRAAVTTLDGISEQSLRLVDAMVYTSDLLTNSVVVMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQT QWLSN+LGT V+KL+P+F W+EAKLSAGVEFL+DAWEILKFLITGVFD++
Sbjct 601 VTGGLVQQTMQWLSNMLGTAVDKLKPVFTWVEAKLSAGVEFLRDAWEILKFLITGVFDVI 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVA+DNIK+CVK F+ VVNKALEMC+DQVTIAG KLR+LNLGEVFIAQS+GLYRQC
Sbjct 661 KGQIQVATDNIKECVKIFLGVVNKALEMCLDQVTIAGTKLRALNLGEVFIAQSRGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPLKAPKEVTFLEGD+HDTVLTSEEVVLK+GELEALETP+DSFT+GA+VG
Sbjct 721 IRGKEQLQLLMPLKAPKEVTFLEGDAHDTVLTSEEVVLKSGELEALETPIDSFTSGAVVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVC+NGLMLLE+++KEQYCALSPGLLATNNVFRLKGGAP+KGVTFGEDTV EVQGYKNV
Sbjct 781 TPVCINGLMLLELENKEQYCALSPGLLATNNVFRLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
+ITFELD RVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLT MGIDLDE
Sbjct 841 KITFELDVRVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTPMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
WSVATFYLFDDAGEE SSRMYCSFYPP +E++ E E+ +ETCEHEYGTEDDY+GL
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPP---DEEEDCEECEDEEETCEHEYGTEDDYKGL 957
Query 961 PLEFGASAETVRVEEEEEE-DWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
PLEFGAS ET VEEEEEE DWLDD E PVNQF GYLKLTDNVAIK
Sbjct 958 PLEFGASTETPHVEEEEEEEDWLDDAIEAEPEPEPLPEE---PVNQFVGYLKLTDNVAIK 1014
Query 1020 CVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGG 1079
C+DIVKEAQSA P VIVNAAN HLKHGGGVAGALNKATNGAMQ ESD+YI+ NGPLTVGG
Sbjct 1015 CIDIVKEAQSAKPTVIVNAANTHLKHGGGVAGALNKATNGAMQNESDEYIRQNGPLTVGG 1074
Query 1080 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1139
SCLLSGHNLA+KCLHVVGPNLNAGED+QLLK AYENFNSQD+LLAPLLSAGIFGAKPLQS
Sbjct 1075 SCLLSGHNLAEKCLHVVGPNLNAGEDVQLLKRAYENFNSQDVLLAPLLSAGIFGAKPLQS 1134
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQ 1199
L++CV+ VRTQVY+AVNDK+LY+Q+V+DYLD+LKP+VE+P +EE P E+ K + V +
Sbjct 1135 LKMCVEIVRTQVYLAVNDKSLYDQIVLDYLDSLKPKVESPNKEEEPKLEEPKA-VQPVAE 1193
Query 1200 KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDA 1259
KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLY DSQNMLRGEDMSFLEKDA
Sbjct 1194 KPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYQDSQNMLRGEDMSFLEKDA 1253
Query 1260 PYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAK 1319
PY+VGDVITSGDITCV+IP+KK+GGTTEML+RALK+VPV EYITTYPGQGCAGYTLEEAK
Sbjct 1254 PYIVGDVITSGDITCVIIPAKKSGGTTEMLARALKEVPVAEYITTYPGQGCAGYTLEEAK 1313
Query 1320 TALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQ 1379
TALKKCKSAFYVLPSE PN KEE+LGTVSWNLREMLAHAEETRKLMPIC+DVRAIMATIQ
Sbjct 1314 TALKKCKSAFYVLPSETPNEKEEVLGTVSWNLREMLAHAEETRKLMPICLDVRAIMATIQ 1373
Query 1380 RKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAA 1439
RKYKGIK+QEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHG NLEEAA
Sbjct 1374 RKYKGIKVQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGLNLEEAA 1433
Query 1440 RCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTEL 1499
RCMRSLKAPAVVSVSSPDAVT YNGYLTSSSKT EE+FVET SLAGSYRDWSYSGQRTEL
Sbjct 1434 RCMRSLKAPAVVSVSSPDAVTAYNGYLTSSSKTPEEYFVETTSLAGSYRDWSYSGQRTEL 1493
Query 1500 GVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQ 1559
GVEFLKRGDKIVYHT SP+EFHLDGEVL LDKLKSLLSLREVKTIKVFTTVDNTNLHT
Sbjct 1494 GVEFLKRGDKIVYHTTGSPIEFHLDGEVLPLDKLKSLLSLREVKTIKVFTTVDNTNLHTH 1553
Query 1560 LVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESF 1619
+VDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHT+DESF
Sbjct 1554 IVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTIDESF 1613
Query 1620 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRA 1679
LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ+EVKFNAPALQEAYYRA
Sbjct 1614 LGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQVEVKFNAPALQEAYYRA 1673
Query 1680 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1739
RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL
Sbjct 1674 RAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTL 1733
Query 1740 TGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFL 1799
GVEAVMYMGTLSYD LKTGVSIPCVCGR+ATQYLVQQESSFVMMSAPPAEYKLQQG FL
Sbjct 1734 KGVEAVMYMGTLSYDELKTGVSIPCVCGRNATQYLVQQESSFVMMSAPPAEYKLQQGAFL 1793
Query 1800 CANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSY 1859
CANEYTGNYQCGHYTHITAKETLYR+DGAHLTKMSEYKGPVTDVFYKETSYTT IKPVSY
Sbjct 1794 CANEYTGNYQCGHYTHITAKETLYRVDGAHLTKMSEYKGPVTDVFYKETSYTTAIKPVSY 1853
Query 1860 KLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTCSNTKFADDLN 1919
KLDGVTYTEIEPKLDGYYKK NAYYTEQPIDLVPTQP+PNASFDNFKLTCSNTKFADDLN
Sbjct 1854 KLDGVTYTEIEPKLDGYYKKGNAYYTEQPIDLVPTQPMPNASFDNFKLTCSNTKFADDLN 1913
Query 1920 QMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTT 1979
QMTGF KPASREL+VTFFPDLNGDVVAIDYRHYS SFKKGAKL+HKPI+WHINQ T KTT
Sbjct 1914 QMTGFKKPASRELTVTFFPDLNGDVVAIDYRHYSTSFKKGAKLVHKPILWHINQTTNKTT 1973
Query 1980 FKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVI 2039
+KPN WCLRCLWSTKPVDTSNSFEVL VEDTQGMDNLACESQ TSEEVVENPT+QKE+I
Sbjct 1974 YKPNIWCLRCLWSTKPVDTSNSFEVLVVEDTQGMDNLACESQTTTSEEVVENPTVQKEII 2033
Query 2040 ECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALGLKTI 2099
ECDVKTTEVVGNVILKPS+EGVKVTQELGHEDLMAAYVE TSITIKKPNELSLALGLKT+
Sbjct 2034 ECDVKTTEVVGNVILKPSEEGVKVTQELGHEDLMAAYVEETSITIKKPNELSLALGLKTL 2093
Query 2100 ATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTF 2159
ATHG AAINSVPWSKILAYVKPFLGQ A+ TSNC K+ QRVF+NYMPYV TLLFQLCTF
Sbjct 2094 ATHGAAAINSVPWSKILAYVKPFLGQTAVITSNCIKKCVQRVFSNYMPYVITLLFQLCTF 2153
Query 2160 TKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGS 2219
TKSTNSRI+ASLPTTIAKNSVKSVAKLCLD INYVKSPKFSKLFTI MWLLLLSICLGS
Sbjct 2154 TKSTNSRIKASLPTTIAKNSVKSVAKLCLDVCINYVKSPKFSKLFTIVMWLLLLSICLGS 2213
Query 2220 LICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYP 2279
L VTA GV LS+ G PSYC+GVRELY+NSSNVTTMDFC+G FPCS+CLSGLDSLDSYP
Sbjct 2214 LTYVTAVLGVCLSSLGVPSYCDGVRELYINSSNVTTMDFCQGYFPCSVCLSGLDSLDSYP 2273
Query 2280 ALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2339
ALETIQVTISSYKLDLT LGLAAEW+LAYMLFTKFFYLLGLSAIMQ FFGYFASHFISNS
Sbjct 2274 ALETIQVTISSYKLDLTFLGLAAEWLLAYMLFTKFFYLLGLSAIMQAFFGYFASHFISNS 2333
Query 2340 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2399
WLMWFIISIVQMAPVSAMVRMYIFFASFYY+WKSYVHIMDGCTSSTCMMCYKRNRATRVE
Sbjct 2334 WLMWFIISIVQMAPVSAMVRMYIFFASFYYVWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2393
Query 2400 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPIN 2459
CTTIVNG+KRSFYVYANGGRGFCK HNWNCLNCDTFC GSTFISDEVARDLSLQFKRPIN
Sbjct 2394 CTTIVNGVKRSFYVYANGGRGFCKAHNWNCLNCDTFCAGSTFISDEVARDLSLQFKRPIN 2453
Query 2460 PTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2519
PTDQS+Y+VDSV VKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV
Sbjct 2454 PTDQSAYVVDSVTVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIV 2513
Query 2520 FDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2579
FDGKSKC+ESA+KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF
Sbjct 2514 FDGKSKCEESAAKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATF 2573
Query 2580 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD 2639
SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD
Sbjct 2574 SVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSD 2633
Query 2640 LEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLS 2699
+EVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSL+WNVKDYMSLS
Sbjct 2634 IEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLVWNVKDYMSLS 2693
Query 2700 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVL 2759
EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGK+VST FKL+LK TLLCVL
Sbjct 2694 EQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKVVSTWFKLLLKVTLLCVL 2753
Query 2760 AALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRG 2819
AAL CY++MPVH+LS+HDGYTNEIIGYKAIQDGVTRDI+STDDCFANKHAGFD+WFSQRG
Sbjct 2754 AALFCYVIMPVHSLSVHDGYTNEIIGYKAIQDGVTRDIVSTDDCFANKHAGFDSWFSQRG 2813
Query 2820 GSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
GSY+NDK+CPVVAAIITREIGFIVPGLPGTVLRA+NGDFLHFLPRVFSAVGNICYTPSKL
Sbjct 2814 GSYRNDKNCPVVAAIITREIGFIVPGLPGTVLRALNGDFLHFLPRVFSAVGNICYTPSKL 2873
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2939
IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII
Sbjct 2874 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSII 2933
Query 2940 QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVD 2999
QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVG+CLSTSGRWVLNNEHYRAL GVFCGVD
Sbjct 2934 QFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGVCLSTSGRWVLNNEHYRALPGVFCGVD 2993
Query 3000 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANA 3059
AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRR FGEYNHVVAANA
Sbjct 2994 AMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRAFGEYNHVVAANA 3053
Query 3060 LLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3119
LLFLMSFTILCL PAYSFLPGVYS+FYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA
Sbjct 3054 LLFLMSFTILCLAPAYSFLPGVYSIFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITA 3113
Query 3120 IYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLT 3179
IYVFCISLKH HWFF+NYL+KRVMFNGVTFSTFEEAALCTFLLNKEMYL+LRSETLLPLT
Sbjct 3114 IYVFCISLKHFHWFFSNYLKKRVMFNGVTFSTFEEAALCTFLLNKEMYLRLRSETLLPLT 3173
Query 3180 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3239
QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL
Sbjct 3174 QYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVL 3233
Query 3240 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLI 3299
QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHV+CTAEDMLNPNY+DLLI
Sbjct 3234 QSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVVCTAEDMLNPNYDDLLI 3293
Query 3300 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3359
RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN
Sbjct 3294 RKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYN 3353
Query 3360 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3419
GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG
Sbjct 3354 GSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEG 3413
Query 3420 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3479
KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY
Sbjct 3414 KFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNY 3473
Query 3480 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3539
EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ
Sbjct 3474 EPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQ 3533
Query 3540 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIA 3599
CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPF LGIMA+A
Sbjct 3534 CSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFALGIMAVA 3593
Query 3600 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3659
ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC
Sbjct 3594 ACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDC 3653
Query 3660 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTS 3719
VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGN+LDQAISMWALVISVTS
Sbjct 3654 VMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAISMWALVISVTS 3713
Query 3720 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3779
NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR
Sbjct 3714 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3773
Query 3780 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3839
YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM
Sbjct 3774 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3833
Query 3840 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3899
SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ
Sbjct 3834 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3893
Query 3900 GAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3959
GAVDIN+LCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAV+NGDSEVVLKKLKK
Sbjct 3894 GAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVSNGDSEVVLKKLKK 3953
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
SLNVAKSEFD DAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN
Sbjct 3954 SLNVAKSEFDHDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4013
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV
Sbjct 4014 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4073
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4139
DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA
Sbjct 4074 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4133
Query 4140 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4199
CTDDNALAYYNN+KGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG
Sbjct 4134 CTDDNALAYYNNAKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4193
Query 4200 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4259
PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD
Sbjct 4194 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4253
Query 4260 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4319
YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF
Sbjct 4254 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4313
Query 4320 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP+MQSADASTFLN
Sbjct 4314 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPMMQSADASTFLN 4372
>sp|P0C6F5|R1A_BC279 Replicase polyprotein 1a OS=Bat coronavirus
279/2005 OX=389167 GN=1a PE=3 SV=1
Length=4388
Score = 6179 bits (16031), Expect = 0.0, Method: Composition-based stats.
Identities = 4092/4389 (93%), Positives = 4234/4389 (96%), Gaps = 16/4389 (0%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESL LGV+EKTHVQLSLPVLQVRDVLVRGFGDSVEEAL+EAREHLKNGTCGLVELEKGV
Sbjct 1 MESLALGVSEKTHVQLSLPVLQVRDVLVRGFGDSVEEALAEAREHLKNGTCGLVELEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDA TNHG+KVVELVAE+DGIQYGRSG TLGVLVPHVGETP+AYRN
Sbjct 61 LPQLEQPYVFIKRSDAQGTNHGYKVVELVAELDGIQYGRSGTTLGVLVPHVGETPVAYRN 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHSYGIDLKSYDLG ELGTDPIEDYEQNWNTKHG G LREL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGIDLKSYDLGVELGTDPIEDYEQNWNTKHGGGVLRELIRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGKSMCTLSEQLDYIESKRGVYCCR+HEHEI W
Sbjct 181 AFTRYVDNNFCGPDGYPLECIKDLLARAGKSMCTLSEQLDYIESKRGVYCCREHEHEIVW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
FTERS+KSYE QTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI
Sbjct 241 FTERSEKSYERQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVA+PQECN+MHLSTLMKCNHCDEVSWQTCDFLKATCE CGTENLV EGPTTCGYL
Sbjct 301 RSVYPVATPQECNDMHLSTLMKCNHCDEVSWQTCDFLKATCEQCGTENLVCEGPTTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
P NAVVKMPCPACQDPE+GPEHSVADYHNHSNIETRLRKGGRT+CFGGCVFAYVGCYNKR
Sbjct 361 PANAVVKMPCPACQDPEVGPEHSVADYHNHSNIETRLRKGGRTKCFGGCVFAYVGCYNKR 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASA+IG+ HTGITGDNVETLNEDL+EIL+R+RVNINIVGDFHLNEEVAIILASF
Sbjct 421 AYWVPRASANIGASHTGITGDNVETLNEDLMEILNRDRVNINIVGDFHLNEEVAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SAST AF+DT+K LDYK+FK IVESCGN+KVT+G+ KGAWNIGQ++S+LTPL GFPSQA
Sbjct 481 SASTCAFVDTVKGLDYKTFKDIVESCGNFKVTRGRAKKGAWNIGQEKSILTPLYGFPSQA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
AGVIRSIF R LD ANHSIPDLQRAA+TILDGISEQSLRL+DAMVYTSDLLTNSVI+MAY
Sbjct 541 AGVIRSIFTRALDTANHSIPDLQRAAITILDGISEQSLRLIDAMVYTSDLLTNSVIVMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
VTGGLVQQ +QWLSN+LGTTV+KL+P+F W+EAKLSAG+EFL+DAWEILKFL+TGVFDIV
Sbjct 601 VTGGLVQQITQWLSNMLGTTVDKLKPVFTWVEAKLSAGIEFLRDAWEILKFLVTGVFDIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
KGQIQVASDN+K+CVK F+DV+NKALEMCIDQV IAGAKLR+LNLGEVFIAQSKGLYRQC
Sbjct 661 KGQIQVASDNLKECVKAFLDVLNKALEMCIDQVIIAGAKLRTLNLGEVFIAQSKGLYRQC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
IRGKEQLQLLMPL+APKEVTF EGDSHDTV TSEEVVLKNGELEALETPVDSFTNGA++G
Sbjct 721 IRGKEQLQLLMPLRAPKEVTFFEGDSHDTVFTSEEVVLKNGELEALETPVDSFTNGAVIG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVCVNGLMLLE+KDKEQYCALSPGLLATNNVF LKGGAP+KGVTFGEDTV EVQGYKNV
Sbjct 781 TPVCVNGLMLLELKDKEQYCALSPGLLATNNVFSLKGGAPVKGVTFGEDTVLEVQGYKNV 840
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
+ITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE
Sbjct 841 KITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCE-HEYGTEDDYQG 959
WSVATFYLFDDAGEE SSRMYCSFYPPDEEE+ + +EEEI E HEYGTEDDY+G
Sbjct 901 WSVATFYLFDDAGEEKLSSRMYCSFYPPDEEEDCEEYEDEEEIPEETCEHEYGTEDDYKG 960
Query 960 LPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
LPLEFGAS E +++ +EE+ D E +PEPEP PEEPVNQFTGYLKLTDNVAIK
Sbjct 961 LPLEFGASTE---IQQVDEEEEEDWLEEAIAAKPEPEPLPEEPVNQFTGYLKLTDNVAIK 1017
Query 1020 CVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGG 1079
CVDIVKEAQ A P VIVNAAN+HLKHGGGVAGALNKATNGAMQ+ESDDYIK NGPLTVGG
Sbjct 1018 CVDIVKEAQHAKPTVIVNAANVHLKHGGGVAGALNKATNGAMQQESDDYIKKNGPLTVGG 1077
Query 1080 SCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQS 1139
SCLLSGHNLAKKC+HVVGPNLNAGED+QLLKAAY NFNSQD+LLAPLLSAGIFGAKPLQS
Sbjct 1078 SCLLSGHNLAKKCMHVVGPNLNAGEDVQLLKAAYANFNSQDVLLAPLLSAGIFGAKPLQS 1137
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTE------ 1193
L++CV+TVRTQVY AVND+ LY+ VV+ YLD+LKP+VE P QE E E
Sbjct 1138 LKMCVETVRTQVYFAVNDQDLYDHVVLGYLDSLKPKVETPTQENLELKEQPAVETLTQEN 1197
Query 1194 ----EKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRG 1249
E V++KPVDV K KA I+EV T+LEETKFLT++LLLFADINGKLY DSQNMLRG
Sbjct 1198 LELEELPVIEKPVDV--KFKARIEEVNTSLEETKFLTSRLLLFADINGKLYQDSQNMLRG 1255
Query 1250 EDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQG 1309
EDM FLEKDAPY+VGDVI+SGDITCV+IP+KKAGGTTEML++ALKKVPV EYITTYPGQG
Sbjct 1256 EDMFFLEKDAPYIVGDVISSGDITCVIIPAKKAGGTTEMLAKALKKVPVSEYITTYPGQG 1315
Query 1310 CAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICM 1369
CAGYTLEEAKTAL+KCKS FYVLPS+ PN KEEILGTVSWNLREMLAHAEETRKLM ICM
Sbjct 1316 CAGYTLEEAKTALRKCKSVFYVLPSKTPNDKEEILGTVSWNLREMLAHAEETRKLMLICM 1375
Query 1370 DVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYV 1429
DV+A+M+TI R+YKGIK+QEGIVDYGVRFFFYTSKEPVASIITKLN LNEPLVTMPIGYV
Sbjct 1376 DVKALMSTIHRRYKGIKVQEGIVDYGVRFFFYTSKEPVASIITKLNLLNEPLVTMPIGYV 1435
Query 1430 THGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRD 1489
THG NLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHF+ETVSLAG YRD
Sbjct 1436 THGLNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFIETVSLAGMYRD 1495
Query 1490 WSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFT 1549
WSYSGQRTELGVEFLKRGDK+VYHT+ SP++FHLDGEVL LDKLKSLLSLREV+TIKVFT
Sbjct 1496 WSYSGQRTELGVEFLKRGDKVVYHTVGSPIQFHLDGEVLLLDKLKSLLSLREVRTIKVFT 1555
Query 1550 TVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAF 1609
TVDNTNLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH HEGKTFFVLPSDDTLRSEAF
Sbjct 1556 TVDNTNLHTQIVDMSMTYGQQFGPTYLDGADVTKIKPHAKHEGKTFFVLPSDDTLRSEAF 1615
Query 1610 EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNA 1669
EYYHTLDESFLGRYMSALNHTKKWKFPQ+GGLTSIKWADNNCYLSSVLLALQQ+EVKFNA
Sbjct 1616 EYYHTLDESFLGRYMSALNHTKKWKFPQIGGLTSIKWADNNCYLSSVLLALQQIEVKFNA 1675
Query 1670 PALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVC 1729
PALQEAYYRARAGDAANFCALILAYSN+TVGELGDVRETMTHLLQHANLESAKRVLNVVC
Sbjct 1676 PALQEAYYRARAGDAANFCALILAYSNRTVGELGDVRETMTHLLQHANLESAKRVLNVVC 1735
Query 1730 KHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPA 1789
K CGQK+TTLTGVEAVMYMGTLSY+ LKTGV+IPC+CGRDATQYLVQQESSFVMMSAPP+
Sbjct 1736 KTCGQKSTTLTGVEAVMYMGTLSYEELKTGVTIPCICGRDATQYLVQQESSFVMMSAPPS 1795
Query 1790 EYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETS 1849
EY LQQG FLCANEYTG+YQCGHYTH+T KETLYRIDGA+LTKMSEYKGPVTDVFYKE S
Sbjct 1796 EYTLQQGAFLCANEYTGSYQCGHYTHVTVKETLYRIDGAYLTKMSEYKGPVTDVFYKEIS 1855
Query 1850 YTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTC 1909
YTTTIKPVSYKLDGV YTEI+PKLD YYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTC
Sbjct 1856 YTTTIKPVSYKLDGVIYTEIQPKLDEYYKKDNAYYTEQPIDLVPTQPLPNASFDNFKLTC 1915
Query 1910 SNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVW 1969
SNTKFADDLNQMTGF KPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPI+W
Sbjct 1916 SNTKFADDLNQMTGFKKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIIW 1975
Query 1970 HINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLACESQQPTSEEVV 2029
HINQ T KTT+KPNTWCLRCLWSTKPV+TSNSFEVL VEDTQGMDNLACESQ PTSEEVV
Sbjct 1976 HINQTTNKTTYKPNTWCLRCLWSTKPVETSNSFEVLEVEDTQGMDNLACESQTPTSEEVV 2035
Query 2030 ENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNE 2089
ENPTIQKEVIECDVKT EVVGNVILKPS+EGVKVTQELGHEDLMAAYVE TSITIKKPNE
Sbjct 2036 ENPTIQKEVIECDVKTIEVVGNVILKPSEEGVKVTQELGHEDLMAAYVEETSITIKKPNE 2095
Query 2090 LSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYV 2149
LSLALGL+T+ATHG AAINSVPWSKILAYVKPFLGQAA+TT+NC KR QRVFNNYMPYV
Sbjct 2096 LSLALGLRTLATHGAAAINSVPWSKILAYVKPFLGQAAVTTTNCIKRCVQRVFNNYMPYV 2155
Query 2150 FTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMW 2209
TLLFQLCTFT+STNSRIRASLPTTIAKNSVKSVAKLCLD INYVKSPKFSKLFTIAMW
Sbjct 2156 ITLLFQLCTFTRSTNSRIRASLPTTIAKNSVKSVAKLCLDVCINYVKSPKFSKLFTIAMW 2215
Query 2210 LLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICL 2269
LLLLSICLGSLI VTAAFGVLLSN G PSYC+GVRE Y+NSSNVTTMDFCEGSF CS+CL
Sbjct 2216 LLLLSICLGSLIYVTAAFGVLLSNLGIPSYCDGVRESYVNSSNVTTMDFCEGSFLCSVCL 2275
Query 2270 SGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFG 2329
+GLDSLDSYPALETIQVTISSYKLDLT LGLAAEW LAYMLFTKFFYLLGLSAIMQVFFG
Sbjct 2276 NGLDSLDSYPALETIQVTISSYKLDLTSLGLAAEWFLAYMLFTKFFYLLGLSAIMQVFFG 2335
Query 2330 YFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMC 2389
YFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFA YY+WKSYVHIMDGCTSSTCMMC
Sbjct 2336 YFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFAFCYYVWKSYVHIMDGCTSSTCMMC 2395
Query 2390 YKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARD 2449
YKRNRATRVECTTIVNGMKRSFYVYANGGRGFCK HNWNCLNCDTFC GSTFISDEVARD
Sbjct 2396 YKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKAHNWNCLNCDTFCAGSTFISDEVARD 2455
Query 2450 LSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNT 2509
LSLQFKRPINPTDQSSY+VDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNT
Sbjct 2456 LSLQFKRPINPTDQSSYVVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNT 2515
Query 2510 KGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFD 2569
KGSLPINVIVFDGKSKCDESA+KSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFD
Sbjct 2516 KGSLPINVIVFDGKSKCDESAAKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFD 2575
Query 2570 AYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVI 2629
AYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVI
Sbjct 2576 AYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVI 2635
Query 2630 ECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLI 2689
ECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLI
Sbjct 2636 ECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLI 2695
Query 2690 WNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKL 2749
WNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVN ITTKISLKGGKIVST FKL
Sbjct 2696 WNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNAITTKISLKGGKIVSTWFKL 2755
Query 2750 MLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHA 2809
MLKATLLCVLAAL CYI+MPVH+LS+HDGYTNEIIGYKAIQDGVTRDI++TDDCFANKHA
Sbjct 2756 MLKATLLCVLAALFCYIIMPVHSLSVHDGYTNEIIGYKAIQDGVTRDIMATDDCFANKHA 2815
Query 2810 GFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAV 2869
GFD+WFSQRGGSY+NDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAV
Sbjct 2816 GFDSWFSQRGGSYRNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAV 2875
Query 2870 GNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDT 2929
GNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDT
Sbjct 2876 GNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDT 2935
Query 2930 RYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYR 2989
RYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE G+CLSTSGRWVLNNEHYR
Sbjct 2936 RYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEAGVCLSTSGRWVLNNEHYR 2995
Query 2990 ALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFG 3049
AL GVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRR FG
Sbjct 2996 ALPGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRAFG 3055
Query 3050 EYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMF 3109
EYNHVVAANALLFLMSFTILCL PAYSFLPGVYS+FYLYLTFYFTNDVSFLAHLQWFAMF
Sbjct 3056 EYNHVVAANALLFLMSFTILCLAPAYSFLPGVYSIFYLYLTFYFTNDVSFLAHLQWFAMF 3115
Query 3110 SPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLK 3169
SPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLK
Sbjct 3116 SPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLK 3175
Query 3170 LRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQP 3229
LRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQP
Sbjct 3176 LRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQP 3235
Query 3230 PQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDM 3289
PQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDM
Sbjct 3236 PQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDM 3295
Query 3290 LNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPG 3349
LNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPG
Sbjct 3296 LNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPG 3355
Query 3350 QTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT 3409
QTFSVLACYNGSPSGVYQCAMRPN+TIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT
Sbjct 3356 QTFSVLACYNGSPSGVYQCAMRPNYTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPT 3415
Query 3410 GVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLND 3469
GVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLND
Sbjct 3416 GVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLND 3475
Query 3470 FNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILED 3529
FNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILED
Sbjct 3476 FNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILED 3535
Query 3530 EFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFL 3589
EFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFL
Sbjct 3536 EFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFL 3595
Query 3590 PFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADT 3649
PFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADT
Sbjct 3596 PFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADT 3655
Query 3650 SLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAIS 3709
SLSGYRLKDCVMYASALVLL+LMTARTVYDDAARRVWTLMNVITLVYKVYYGN+LDQAIS
Sbjct 3656 SLSGYRLKDCVMYASALVLLVLMTARTVYDDAARRVWTLMNVITLVYKVYYGNSLDQAIS 3715
Query 3710 MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC 3769
MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC
Sbjct 3716 MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC 3775
Query 3770 YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC 3829
YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC
Sbjct 3776 YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC 3835
Query 3830 IKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMV 3889
IKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMV
Sbjct 3836 IKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMV 3895
Query 3890 SLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
SLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD
Sbjct 3896 SLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3955
Query 3950 SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTM 4009
SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTM
Sbjct 3956 SEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTM 4015
Query 4010 LFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYA 4069
LFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYA
Sbjct 4016 LFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYA 4075
Query 4070 SALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQM 4129
SALWEIQQVVDADSKIVQLSEINMDNS NLAWPLIVTALRANSAVKLQNNELSPVALRQM
Sbjct 4076 SALWEIQQVVDADSKIVQLSEINMDNSQNLAWPLIVTALRANSAVKLQNNELSPVALRQM 4135
Query 4130 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4189
SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP
Sbjct 4136 SCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPP 4195
Query 4190 CRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAF 4249
CRFVTDTP+GPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANS VLSFCAF
Sbjct 4196 CRFVTDTPRGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSAVLSFCAF 4255
Query 4250 AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC 4309
AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC
Sbjct 4256 AVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRC 4315
Query 4310 HIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQ 4369
HIDHPNPKGFCDLKGKYVQIP TCANDPVGFTL+NTVCTVCG WKGYGCSCDQLREP+MQ
Sbjct 4316 HIDHPNPKGFCDLKGKYVQIPATCANDPVGFTLKNTVCTVCGTWKGYGCSCDQLREPMMQ 4375
Query 4370 SADASTFLN 4378
SADASTFLN
Sbjct 4376 SADASTFLN 4384
>sp|P0DTC1|R1A_SARS2 Replicase polyprotein 1a OS=Severe acute
respiratory syndrome coronavirus 2 OX=2697049 PE=1 SV=1
Length=4405
Score = 5962 bits (15468), Expect = 0.0, Method: Composition-based stats.
Identities = 3545/4408 (80%), Positives = 3944/4408 (89%), Gaps = 37/4408 (1%)
Query 1 MESLVLGVNEKTHVQLSLPVLQVRDVLVRGFGDSVEEALSEAREHLKNGTCGLVELEKGV 60
MESLV G NEKTHVQLSLPVLQVRDVLVRGFGDSVEE LSEAR+HLK+GTCGLVE+EKGV
Sbjct 1 MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGV 60
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYRN 120
LPQLEQPYVFIKRSDA + HGH +VELVAE++GIQYGRSG TLGVLVPHVGE P+AYR
Sbjct 61 LPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRK 120
Query 121 VLLRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGG 180
VLLRKNGNKGAGGHSYG DLKS+DLGDELGTDP ED+++NWNTKH SG REL RELNGG
Sbjct 121 VLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGG 180
Query 181 AVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAW 240
A TRYVDNNFCGPDGYPL+CIKD LARAGK+ CTLSEQLD+I++KRGVYCCR+HEHEIAW
Sbjct 181 AYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAW 240
Query 241 FTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRI 300
+TERS+KSYE QTPFEIK AKKFDTF GECP FVFPLNS +K IQPRVEKKK +GFMGRI
Sbjct 241 YTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRI 300
Query 301 RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYL 360
RSVYPVASP ECN M LSTLMKC+HC E SWQT DF+KATCE CGTENL EG TTCGYL
Sbjct 301 RSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYL 360
Query 361 PTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKR 420
P NAVVK+ CPAC + E+GPEHS+A+YHN S ++T LRKGGRT FGGCVF+YVGC+NK
Sbjct 361 PQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKC 420
Query 421 AYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASF 480
AYWVPRASA+IG HTG+ G+ E LN++LLEIL +E+VNINIVGDF LNEE+AIILASF
Sbjct 421 AYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASF 480
Query 481 SASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQA 540
SASTSAF++T+K LDYK+FK IVESCGN+KVTKGK KGAWNIG+Q+S+L+PL F S+A
Sbjct 481 SASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEA 540
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
A V+RSIF+RTL+ A +S+ LQ+AA+TILDGIS+ SLRL+DAM++TSDL TN++++MAY
Sbjct 541 ARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAY 600
Query 601 VTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIV 660
+TGG+VQ TSQWL+N+ GT EKL+P+ +W+E K GVEFL+D WEI+KF+ T +IV
Sbjct 601 ITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIV 660
Query 661 KGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQC 720
GQI + IK+ V+ F +VNK L +C D + I GAKL++LNLGE F+ SKGLYR+C
Sbjct 661 GGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKC 720
Query 721 IRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
++ +E+ LLMPLKAPKE+ FLEG++ T + +EEVVLK G+L+ LE P +VG
Sbjct 721 VKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVG 780
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNV 840
TPVC+NGLMLLEIKD E+YCAL+P ++ TNN F LKGGAP K VTFG+DTV EVQGYK+V
Sbjct 781 TPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTK-VTFGDDTVIEVQGYKSV 839
Query 841 RITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDE 900
ITFELDER+DKVLNEKCS YTVE GTEV EFACVVA+AV+KTLQPVS+LLT +GIDLDE
Sbjct 840 NITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDE 899
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
WS+AT+YLFD++GE +S MYCSFYPPDE+EE+ EEE T ++EYGTEDDYQG
Sbjct 900 WSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPST-QYEYGTEDDYQGK 958
Query 961 PLEFGASAETVRVEEEEEEDWLDDTTEQ-------------------SEIEP--EPEPTP 999
PLEFGA++ ++ EEE+EEDWLDD ++Q E++P E E TP
Sbjct 959 PLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTP 1018
Query 1000 ---EEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKA 1056
VN F+GYLKLTDNV IK DIV+EA+ P V+VNAAN++LKHGGGVAGALNKA
Sbjct 1019 VVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKA 1078
Query 1057 TNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF 1116
TN AMQ ESDDYI NGPL VGGSC+LSGHNLAK CLHVVGPN+N GEDIQLLK+AYENF
Sbjct 1079 TNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENF 1138
Query 1117 NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPR- 1175
N ++LLAPLLSAGIFGA P+ SL+VCV TVRT VY+AV DK LY+++V +L+ +
Sbjct 1139 NQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQ 1198
Query 1176 -----VEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLL 1230
E PK+E P +SK SV Q+ D K KIKAC++EVTTTLEETKFLT LL
Sbjct 1199 VEQKIAEIPKEEVKPFITESK---PSVEQRKQDDK-KIKACVEEVTTTLEETKFLTENLL 1254
Query 1231 LFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLS 1290
L+ DING L+ DS ++ D++FL+KDAPY+VGDV+ G +T VVIP+KKAGGTTEML+
Sbjct 1255 LYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLA 1314
Query 1291 RALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWN 1350
+AL+KVP D YITTYPGQG GYT+EEAKT LKKCKSAFY+LPS N K+EILGTVSWN
Sbjct 1315 KALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWN 1374
Query 1351 LREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASI 1410
LREMLAHAEETRKLMP+C++ +AI++TIQRKYKGIKIQEG+VDYG RF+FYTSK VAS+
Sbjct 1375 LREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASL 1434
Query 1411 ITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSS 1470
I LN LNE LVTMP+GYVTHG NLEEAAR MRSLK PA VSVSSPDAVT YNGYLTSSS
Sbjct 1435 INTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS 1494
Query 1471 KTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSL 1530
KT EEHF+ET+SLAGSY+DWSYSGQ T+LG+EFLKRGDK VY+T +P FHLDGEV++
Sbjct 1495 KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYT-SNPTTFHLDGEVITF 1553
Query 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNH 1590
D LK+LLSLREV+TIKVFTTVDN NLHTQ+VDMSMTYGQQFGPTYLDGADVTKIKPH +H
Sbjct 1554 DNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSH 1613
Query 1591 EGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN 1650
EGKTF+VLP+DDTLR EAFEYYHT D SFLGRYMSALNHTKKWK+PQV GLTSIKWADNN
Sbjct 1614 EGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNN 1673
Query 1651 CYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMT 1710
CYL++ LL LQQ+E+KFN PALQ+AYYRARAG+AANFCALILAY NKTVGELGDVRETM+
Sbjct 1674 CYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMS 1733
Query 1711 HLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDA 1770
+L QHANL+S KRVLNVVCK CGQ+ TTL GVEAVMYMGTLSY+ K GV IPC CG+ A
Sbjct 1734 YLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQA 1793
Query 1771 TQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHL 1830
T+YLVQQES FVMMSAPPA+Y+L+ GTF CA+EYTGNYQCGHY HIT+KETLY IDGA L
Sbjct 1794 TKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALL 1853
Query 1831 TKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPID 1890
TK SEYKGP+TDVFYKE SYTTTIKPV+YKLDGV TEI+PKLD YYKKDN+Y+TEQPID
Sbjct 1854 TKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPID 1913
Query 1891 LVPTQPLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYR 1950
LVP QP PNASFDNFK C N KFADDLNQ+TG+ KPASREL VTFFPDLNGDVVAIDY+
Sbjct 1914 LVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYK 1973
Query 1951 HYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDT 2010
HY+ SFKKGAKLLHKPIVWH+N AT K T+KPNTWC+RCLWSTKPV+TSNSF+VL ED
Sbjct 1974 HYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDA 2033
Query 2011 QGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHE 2070
QGMDNLACE +P SEEVVENPTIQK+V+EC+VKTTEVVG++ILKP++ +K+T+E+GH
Sbjct 2034 QGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHT 2093
Query 2071 DLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITT 2130
DLMAAYV+N+S+TIKKPNELS LGLKT+ATHG+AA+NSVPW I Y KPFL + TT
Sbjct 2094 DLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTT 2153
Query 2131 SNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDA 2190
+N R RV NYMPY FTLL QLCTFT+STNSRI+AS+PTTIAKN+VKSV K CL+A
Sbjct 2154 TNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEA 2213
Query 2191 GINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNS 2250
NY+KSP FSKL I +W LLLS+CLGSLI TAA GVL+SN G PSYC G RE YLNS
Sbjct 2214 SFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNS 2273
Query 2251 SNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYML 2310
+NVT +C GS PCS+CLSGLDSLD+YP+LETIQ+TISS+K DLT GL AEW LAY+L
Sbjct 2274 TNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYIL 2333
Query 2311 FTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYI 2370
FT+FFY+LGL+AIMQ+FF YFA HFISNSWLMW II++VQMAP+SAMVRMYIFFASFYY+
Sbjct 2334 FTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYV 2393
Query 2371 WKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCL 2430
WKSYVH++DGC SSTCMMCYKRNRATRVECTTIVNG++RSFYVYANGG+GFCK HNWNC+
Sbjct 2394 WKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCV 2453
Query 2431 NCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTY 2490
NCDTFC GSTFISDEVARDLSLQFKRPINPTDQSSYIVDSV VKNG++HLYFDKAGQKTY
Sbjct 2454 NCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTY 2513
Query 2491 ERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLD 2550
ERH LSHFVNLDNLRANNTKGSLPINVIVFDGKSKC+ES++KSASVYYSQLMCQPILLLD
Sbjct 2514 ERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLD 2573
Query 2551 QALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTF 2610
QALVSDVGDS EV+VKMFDAYV+TFS+TF+VPMEKLK LVATA +ELAK V+LD VLSTF
Sbjct 2574 QALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTF 2633
Query 2611 VSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACID 2670
+SAARQG VD+DV+TKDV+ECLKLSH SD+EVTGDSCNN+MLTYNKVENMTPRDLGACID
Sbjct 2634 ISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACID 2693
Query 2671 CNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNV 2730
C+ARHINAQVAKSHN++LIWNVKD+MSLSEQLRKQIRSAAKKNN+PF+LTCATTRQVVNV
Sbjct 2694 CSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNV 2753
Query 2731 ITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
+TTKI+LKGGKIV+ K ++K TL+ + A + Y++ PVH +S H +++EIIGYKAI
Sbjct 2754 VTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAID 2813
Query 2791 DGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTV 2850
GVTRDI STD CFANKHA FD WFSQRGGSY NDK+CP++AA+ITRE+GF+VPGLPGT+
Sbjct 2814 GGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTI 2873
Query 2851 LRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYC 2910
LR NGDFLHFLPRVFSAVGNICYTPSKLIEY+DFATSACVLAAECTIFKDA GKPVPYC
Sbjct 2874 LRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYC 2933
Query 2911 YDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSE 2970
YDTN+LEGS++Y LRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFD+EYCRHGTCERSE
Sbjct 2934 YDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSE 2993
Query 2971 VGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGII 3030
G+C+STSGRWVLNN++YR+L GVFCGVDA+NL+ N+FTPL+QP+GALD+SAS+VAGGI+
Sbjct 2994 AGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIV 3053
Query 3031 AILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLT 3090
AI+VTC AYYFM+FRR FGEY+HVVA N LLFLMSFT+LCL P YSFLPGVYSV YLYLT
Sbjct 3054 AIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLT 3113
Query 3091 FYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFS 3150
FY TNDVSFLAH+QW MF+P+VPFWIT Y+ CIS KH +WFF+NYL++RV+FNGV+FS
Sbjct 3114 FYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFS 3173
Query 3151 TFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCH 3210
TFEEAALCTFLLNKEMYLKLRS+ LLPLTQYNRYLALYNKYKYFSGA+DTTSYREAACCH
Sbjct 3174 TFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCH 3233
Query 3211 LAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3270
LAKALNDFSNSG+DVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL
Sbjct 3234 LAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3293
Query 3271 WLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLK 3330
WLDD VYCPRHVICT+EDMLNPNYEDLLIRKSNH+FLVQAGNVQLRVIGHSMQNC+L+LK
Sbjct 3294 WLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLK 3353
Query 3331 VDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGF 3390
VDT+NPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN TIKGSFLNGSCGSVGF
Sbjct 3354 VDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGF 3413
Query 3391 NIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA 3450
NIDYDCVSFCYMHHMELPTGVHAGTDLEG FYGPFVDRQTAQAAGTDTTIT+NVLAWLYA
Sbjct 3414 NIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYA 3473
Query 3451 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA+LKE
Sbjct 3474 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKE 3533
Query 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLI 3570
LLQNGMNGRTILGS +LEDEFTPFDVVRQCSGVTFQ K+ +KGTHHW+LLT LTSLL+
Sbjct 3534 LLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLV 3593
Query 3571 LVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMV 3630
LVQSTQWSLFFF+YENAFLPF +GI+A++A AM+ VKHKHAFLCLFLLPSLATVAYFNMV
Sbjct 3594 LVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMV 3653
Query 3631 YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMN 3690
YMPASWVMRIMTWL++ DTSLSG++LKDCVMYASA+VLLILMTARTVYDD ARRVWTLMN
Sbjct 3654 YMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMN 3713
Query 3691 VITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
V+TLVYKVYYGNALDQAISMWAL+ISVTSNYSGVVTT+MFLAR IVF+CVEY P+ FITG
Sbjct 3714 VLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITG 3773
Query 3751 NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKS 3810
NTLQCIMLVYCFLGY C CYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPK+
Sbjct 3774 NTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKN 3833
Query 3811 SIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3870
SIDAFKLNIKLLG+GGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ
Sbjct 3834 SIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQ 3893
Query 3871 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPS 3930
LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDIN+LCEEMLDNRATLQAIASEFSSLPS
Sbjct 3894 LHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPS 3953
Query 3931 YAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 3990
YAA+ATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY
Sbjct 3954 YAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMY 4013
Query 3991 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4050
KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV
Sbjct 4014 KQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVV 4073
Query 4051 VPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRA 4110
+PDY TYKNTCDG TFTYASALWEIQQVVDADSKIVQLSEI+MDNSPNLAWPLIVTALRA
Sbjct 4074 IPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRA 4133
Query 4111 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKW 4170
NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYN +KGGRFVLALLSD QDLKW
Sbjct 4134 NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKW 4193
Query 4171 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4230
ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ
Sbjct 4194 ARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQ 4253
Query 4231 AGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4290
AGNATEVPANSTVLSFCAFAVD AKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE
Sbjct 4254 AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPE 4313
Query 4291 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVC 4350
ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL+NTVCTVC
Sbjct 4314 ANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVC 4373
Query 4351 GMWKGYGCSCDQLREPLMQSADASTFLN 4378
GMWKGYGCSCDQLREP++QSADA +FLN
Sbjct 4374 GMWKGYGCSCDQLREPMLQSADAQSFLN 4401
>sp|P0C6T5|R1A_BCHK5 Replicase polyprotein 1a OS=Bat coronavirus
HKU5 OX=694008 GN=1a PE=3 SV=1
Length=4481
Score = 4843 bits (12563), Expect = 0.0, Method: Composition-based stats.
Identities = 1532/4565 (34%), Positives = 2357/4565 (52%), Gaps = 304/4565 (7%)
Query 9 NEKT--HVQLSLPVLQVRDVLV---RGFGDSVEEALSEAREHLKNGTCGLV--ELEKGVL 61
EK HV L + D+++ F D E A E L G+ L + KG +
Sbjct 22 TEKRTDHVSLKASLCDAGDLVLKISPWFMDG-ESAYKHVSEQLSKGSKLLFVPQTLKGFI 80
Query 62 PQLEQPYVFIKRSDALSTNHGHKVVELVAEMDGIQYGRSGITL-----GVLVPHVGETPI 116
L P V++ T +V +A + G G TL G+ P +
Sbjct 81 RHLPGPRVYLVERLTGGTYSDPFMVNQLAYQNAAGEGVIGTTLQGKRVGMFFPFDADLVT 140
Query 117 AYRNVLLRKNGNKGAGGHSYGIDLKSY------DLGDELGTDPIEDYEQNWNTKHGSGAL 170
LLRK KG GG+ + Y DL D L DP Y Q+
Sbjct 141 GEFQFLLRK---KGFGGNRFRDAPWDYNWTPYSDLMDALEADPCGKYSQS---------- 187
Query 171 RELTRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAG--KSMCTLSEQLDYIESKRGV 228
L ++L GG T +D CG +G P+ +A G K +E +S R +
Sbjct 188 --LLKKLVGGDFTP-IDQYMCGKNGKPIAEFAALMASEGITKLADVEAEVKSRTDSDRYI 244
Query 229 YCCRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRV 288
++ + I W +R D +Y Q+ F + S + DT + + P+ F + S+++VI P
Sbjct 245 -VFKNKLYRIVWNVQRKDVAYSKQSAFTMNSIVQLDTME-DVPRHSFTIGSEIQVIAPST 302
Query 289 EKKKTEGFMGRIRSVYPVASPQ---ECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCG 345
+ + R +Y Q E N ++ S + C C + SW T + ++ CG
Sbjct 303 AVQANGHLNLKQRLLYAFYGKQAVSEPNYIYHSAYVDCTSCGKGSWLTGNAVQGFACDCG 362
Query 346 TENLVIE-GPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRT- 403
+ + G + NAV+ CP +D E +H++ + + + G+T
Sbjct 363 AHYCANDVDLQSSGLVRKNAVLLTTCPCNKDGEC--KHTLPQLVSMMTDKCDVEVVGKTF 420
Query 404 -RCFGGCVFAYVGCYNKRAYWVPRASA-------DIGSGHTGITGDNVETLNEDLLEILS 455
+GG ++AY+GC +++PRA + I +G TG ET N L
Sbjct 421 ILTYGGVIYAYMGCSGGTMHFIPRAKSCVSKIGDAIFTGCTGTWSKVCETAN----LFLE 476
Query 456 RERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGK 515
R + IN V +F L E V +L+ ++S D ++ ++ + + G + VT G
Sbjct 477 RAQHAINFVNEFVLTETVVALLSGTTSSIEELRDLCRNATFEKVRDYLTPRG-WIVTMGS 535
Query 516 PVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISE 575
++G N+G +C A ++ S + + L + LD ++
Sbjct 536 YIEGVINVGA-----AGVCNAALNAPFIVLSGLGESFKKVAATPWKLCSSLRETLDHYAD 590
Query 576 QSLRLV-------DAMVYTSDLLTNSVII--MAYVTGGLVQQTSQWLSNLLGT-TVEKLR 625
V D YT+ LL +V+ AY V + + L+NL+ + +
Sbjct 591 SITYRVFPYDIPCDVTDYTALLLDCAVLTGASAYFVARYVDEKVEQLTNLVFSSCQSAVA 650
Query 626 PIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKA 685
+ + A +F+ D + ++K + ++ V D +K F+ +++KA
Sbjct 651 AFVQACMSTYKATAKFISDMFTLIKVVSERLYVYTSVGFVVVGDYSSQLLKQFMHILSKA 710
Query 686 LEMCIDQVTIAGAKLRSL--NLGEVFIAQSKGLYRQCIRGK---EQLQLLMPLK-APKEV 739
+++ V+ AG+KL S+ N + + S Y +G+ +Q L++P + K++
Sbjct 711 MQLLHTTVSWAGSKLPSVVYNGRDSLVFPSGTYYCVSTQGRSLQDQFDLVIPGDLSKKQI 770
Query 740 TFLEGDSHDTVLTSE----EVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLE-IK 794
LE + T + + V + G+LE P + +VG V ++ + + ++
Sbjct 771 GILEPTPNSTTVDKKINTNVVEVVVGQLE----PTKEHSPELVVGDYVIISNKIFVRSVE 826
Query 795 DKE--QYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDERVDK 852
D E Y + G + +FRLKGGAP KGV FG + E+ ++V + +++ +D
Sbjct 827 DSETVFYPLCTDGKIV-PTLFRLKGGAPPKGVKFGGEQTKEITAVRSVSVDYDVHPVLDA 885
Query 853 VL-NEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDD 911
+L + + +TVE V +F VV + V++ L + G DL++++ Y+++
Sbjct 886 LLAGSELATFTVEKDLPVKDFVDVVKDEVIELLSKLLRGYNVDGFDLEDFADTPCYVYNA 945
Query 912 AGEENFSSRMYCSFYPPDEEEE--DDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAE 969
G+ +SS M S P +E EE DD E+E + E E E+D + A+ E
Sbjct 946 EGDLAWSSTMTFSVNPVEEVEEECDDDYVEDEYLSE----EMLVEEDEN----SWAAAVE 997
Query 970 TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQS 1029
V E+ + D L + SE P + V + T+ V + +++ +Q
Sbjct 998 AVIPMEDVQLDTLVAEIDVSE--------PADDVAEQAS----TEEVEVPSACVLEASQV 1045
Query 1030 ANPMVIVN-----AANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLS 1084
AN + + +++I L A A + A ++ KL+ VG
Sbjct 1046 ANAAEVESCEAEVSSSIPLHEDANAAKANDCAEGMPALDSTETVSKLSVDTPVGD----- 1100
Query 1085 GHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
V + + + + + +S+ ++ P + P ++L V
Sbjct 1101 ----------VTQDDATSSNATVISEDVHTATHSKGLVAVPEVV-------PEKALGTSV 1143
Query 1145 QTVRTQVYIAVNDKALYEQ--VVMDYLDNLKP-RVEAPKQEEPPNTEDSKTEEKSVVQKP 1201
+ +R+ V + +L ++ V++ + KP RV+ PK E P V
Sbjct 1144 ERMRSTSEWTVVETSLKQETAVIVKNDSSAKPQRVKKPKAENPLKNFKHIVLNNDVTLVF 1203
Query 1202 VDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPY 1261
D +A D + T L I + S +++ E ++ P
Sbjct 1204 GDAIAVARATEDCILVNAANTH-----LKHGGGIAAAIDRASGGLVQAESDDYVNFYGPL 1258
Query 1262 MVGDVIT------SGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTL 1315
VGD + I VV P +A ++L R K ++Y AG
Sbjct 1259 NVGDSTLLKGHGLATGILHVVGPDARANQDIQLLKRCYKAF--NKYPLVVSPLISAGIFC 1316
Query 1316 EEAKTALKKCKSA-----FYVLPSE-------APNAKEEI-LGTVSWNLREMLAHAEETR 1362
E + +L+ S + V+ SE AP + W R ++ +A+
Sbjct 1317 VEPRVSLEYLLSVVHTKTYVVVNSEKVYNDLAAPKPPTGLTYSHEGW--RGIIRNAKSFG 1374
Query 1363 KLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLV 1422
IC D A ++ + + + VD GV+++ Y+SK+P+ IIT N+ + +
Sbjct 1375 FTCFICTDQSANAKLLKGRGVDLTKKTQTVD-GVKYYLYSSKDPLTDIITAANAC-KGIC 1432
Query 1423 TMPIGYVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVS 1482
MPIGYVTHG +L +A + ++ + P V ++S D V N + + +T E+ F+ TV
Sbjct 1433 AMPIGYVTHGLDLAQAGQQVKKITVPYVCLLASKDQVPILNSDV--AVQTPEQSFINTVI 1490
Query 1483 LAGSYRDWSY-SGQRTELGVEF---LKRGDKIV------YHTLESPVEFHLDGEVLSLDK 1532
G Y W +G+ GV + L D+ + ++ ++ + D SL+K
Sbjct 1491 ANGGYHCWHLVTGELIVKGVSYRKLLNWSDQTICYADNKFYVVKGQIALPFD----SLEK 1546
Query 1533 LKSLLSLR--EVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNH 1590
++ L+ R + K + V T+D N T +++ + TY Q G + G+D++ P
Sbjct 1547 CRTYLTSRAAQQKNVDVLVTIDGVNFRTVVLNNTTTYRVQLGSVFYKGSDISDTIPTEKM 1606
Query 1591 EGKTFFVLPSDDTLRSEAF-EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADN 1649
G+ ++ + E Y T D +FL RY S L KKWK+ G+ S+K N
Sbjct 1607 SGEAVYLADNLSEAEKAVLSEVYGTADTAFLHRYYSLLALVKKWKYTVHDGVKSLKLNSN 1666
Query 1650 NCYLSSVLLALQQLE-VKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRET 1708
NCY++ +L L L+ +KF PALQ AY + + GD+ F ALI+AY + T GE D
Sbjct 1667 NCYVNVTMLMLDMLKEIKFIVPALQAAYLKHKGGDSTEFIALIMAYGDCTYGEPDDASRL 1726
Query 1709 MTHLLQHANLES-AKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCG 1767
+ +L A L + AK V C CG + TT TG++A +Y+G S D L C CG
Sbjct 1727 LHTILSKAELTTQAKMVWRQWCNVCGVQDTTTTGLKACIYVGMNSLDELHATHEECCQCG 1786
Query 1768 RDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTG-------NYQCGHYTHITAKE 1820
+ LV+ + ++++S + + +YT GHY H+ K+
Sbjct 1787 DVRKRQLVEHNAPWLLLSGLNEAKVMTPTSQSAGPDYTAFNVFQGVETSVGHYLHVRVKD 1846
Query 1821 TL-YRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKK 1879
L Y+ D L+K S+ K +TDV+Y + Y+ V Y LDG T+ +++P L +Y K
Sbjct 1847 NLLYKYDSGSLSKTSDMKCKMTDVYYPKQRYSADCNVVVYSLDGNTWADVDPDLSAFYMK 1906
Query 1880 DNAYYTEQP-IDLVPTQPLPNASFDNFKLTCSNTKFADD-----LNQMTGF--TKPASRE 1931
D Y+T++P I+ P L + + N L + D N + GF +KP S++
Sbjct 1907 DGKYFTKKPVIEYSPATILSGSVYTNSCLVGHDGTIGSDAISSSFNNLLGFDNSKPVSKK 1966
Query 1932 LSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLW 1991
L+ +FFPD GDV+ +Y Y +K GA L KPI+W N K N LR ++
Sbjct 1967 LTYSFFPDFEGDVILTEYSTYDPIYKNGAMLHGKPILWVNNSKFDSALNKFNRATLRQVY 2026
Query 1992 STKPVDTSNSFEVLAVEDTQGMDNLAC-ESQQPTSE-EVVENPTIQKEVIECD-VKTTEV 2048
PV N + VL Q ++ A E +P S +V E+ + +I+C +K V
Sbjct 2027 DIAPVTLENKYTVLQDNQIQQVEVEAPKEDAKPQSPVQVAEDIDNKLPIIKCKGLKKPFV 2086
Query 2049 VGNVILKPSDEGVKVTQELGHEDLMAAYVE-NTSITIKKPNELSLALGLKTIATHG---I 2104
+GV V LG +DL A YV+ N + + K N S + T+ I
Sbjct 2087 KDGYSFVNDPQGVNVIDTLGIDDLRALYVDRNLRLIVLKENNWSALFNIHTVEKGDLSVI 2146
Query 2105 AAINSVPWS-KILAYVKPFLGQAAITTSNCAK-------RLAQRVFNN--YMPYVFTLLF 2154
AA S+ KIL Q A T N R+ + V N + F LL
Sbjct 2147 AASGSITRRVKILLGASSLFAQFASVTVNVTTAMGKALGRMTRNVITNTGIIGQGFALLK 2206
Query 2155 QL----CTFTKSTN-SRIRASLPTTIAKNSVKS-VAKLCLDAGINYVKSPKFSKLFTIAM 2208
L TF KS N S ++ + V + V K C A + V KF ++ +
Sbjct 2207 MLLILPFTFWKSKNQSTVKVEVGALRTAGIVTTNVVKQCASAAYD-VLVVKFKRIDWKST 2265
Query 2209 WLLLLSIC------------------LGSLICVTAAFGVLL------SNFGAPSYCNGVR 2244
LL IC L S + + A G+L S G S C+G+
Sbjct 2266 LRLLFLICTTGLLLSSLYYLFLFHQVLTSDVMLDGAEGMLATYRELRSYLGIHSLCDGMV 2325
Query 2245 ELYLNSSNVTTMDFCEG-SFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAE 2303
E Y N S DFC S C+ CL G DSL Y A + IQ ++SY +++ + E
Sbjct 2326 EAYRNVS-YDVNDFCSNRSALCNWCLIGQDSLTRYSAFQMIQTHVTSYVINIDWVWFVME 2384
Query 2304 WVLAYMLFTKFFYLLGLSAIMQVFFGYFAS--HFISNSWLMWFIISIVQMAPVSAMVRMY 2361
+ LAY+L+T F +L L Q FF Y + ++ S ++L+ V P+ +VR+Y
Sbjct 2385 FALAYVLYTSTFNVLLLVVSSQYFFSYTGAFVNWRSYNYLVSGYFFCVTHIPLLGLVRIY 2444
Query 2362 IFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGF 2421
F A +++ + Y H+++GC + C++CYKRNR TRVE +T+V G KR+FY+ ANGG F
Sbjct 2445 NFLACLWFLRRFYNHVINGCKDTACLLCYKRNRLTRVEASTVVCGSKRTFYIVANGGTSF 2504
Query 2422 CKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLY 2481
C HNWNC++CDT G+TFI +EVA DL+ +R + PTD+S Y V+SV VK+ + L+
Sbjct 2505 CCRHNWNCVDCDTAGIGNTFICEEVANDLTTSLRRLVKPTDKSHYYVESVTVKDSVVQLH 2564
Query 2482 FDKAGQKTYERHPLSHFVNLDNLR----ANNTKGSLPINVIVFDGKSKCDESASKSASVY 2537
+ + G YER+PL +F NLD L+ G N +++D + E+ ++SA VY
Sbjct 2565 YSREGASCYERYPLCYFTNLDKLKFKEVCKTPTGIPEHNFLIYDSSDRGQENLARSACVY 2624
Query 2538 YSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSEL 2597
YSQ++ +P+LL+D +V+ VGDS E++ KM D+YV++F + F V +KL LVATA +
Sbjct 2625 YSQVLSKPMLLVDSNMVTTVGDSREIASKMLDSYVNSFISLFGVNRDKLDKLVATARDCV 2684
Query 2598 AKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNK 2656
+G V+ TF AAR V++DV+T +++ L+ ++ DL++T + NN++ +Y K
Sbjct 2685 KRGDDFQTVIKTFTDAARGPAGVESDVETSSIVDALQYAYKHDLQLTTEGFNNYVPSYIK 2744
Query 2657 VENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIP 2716
+++ DLG ID NA +N ++ N + IWN DYM LS+ L++QIR A +K NIP
Sbjct 2745 PDSVATADLGCLIDLNAASVNQTSIRNANGACIWNSSDYMKLSDSLKRQIRIACRKCNIP 2804
Query 2717 FRLTCATTRQVVNVITTKIS---LKGGK------IVSTCFKLMLKATLLCVLAALVCYIV 2767
FRLT + R N+++ K S L GG + +K TL+ A++ Y+
Sbjct 2805 FRLTTSRLRSADNILSVKFSATKLSGGAPKWLLKLRDFTWKSYCVVTLVVFAMAVLSYLC 2864
Query 2768 MPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQR-GGSYKNDK 2826
+P +S + + I+ YK +++G+ RDI +D CFANK+ F WF++ GG + ND
Sbjct 2865 LPAFNMSQVSFHEDRILTYKVVENGIIRDITPSDTCFANKYQSFSKWFNEHYGGLFNNDI 2924
Query 2827 SCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFA 2886
SCPV A+I G VP LP V + + F+ RVF++ N+CYTP+ I Y F+
Sbjct 2925 SCPVTVAVIAGVAGARVPNLPANV-AWVGRQIVLFVSRVFASSNNVCYTPTAEIPYERFS 2983
Query 2887 TSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTY 2945
S CVLA+ECT+F+DA GK PYCYD +L G+ +Y +++P RY + D I+FP
Sbjct 2984 DSGCVLASECTLFRDAEGKINPYCYDPTVLPGASAYDQMKPHVRYDMYDSDMYIKFPEVV 3043
Query 2946 LEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIA 3005
E ++R+ T YCR G+CE + G+C++T+G W + N+HY GV+CG + +++
Sbjct 3044 FESTLRITKTLATRYCRFGSCEDANEGVCITTNGSWAIYNDHYANKPGVYCGDNYFDIVR 3103
Query 3006 NIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMS 3065
+ L QPV +S S+ G ++ I +T A YY K +R +Y L++
Sbjct 3104 RLGLSLFQPVTYFQLSTSLALGVMLCIFLTIAFYYVNKVKRALADYTQCAVVAVAAALLN 3163
Query 3066 FTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCI 3125
LC V + L Y+ Y Y TFY T + +F+ H+ WF MF +VP W+ Y+ +
Sbjct 3164 SLCLCFVVSNPLLVLPYTALYYYATFYLTGEPAFVMHVSWFVMFGTVVPIWMVFAYIVGV 3223
Query 3126 SLKHCHWFFNNYLRK--RVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNR 3183
L+H W + +K V +G +F++AA F++NK+ Y+ LR+ + YNR
Sbjct 3224 CLRHLLWVMAYFSKKHVEVFTDGKLNCSFQDAAANIFVINKDTYVALRNS--ITQDSYNR 3281
Query 3184 YLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGF 3243
YL+++NKYKY+SGA+DT SYREA+ HL KAL +S +G+DVL+QPP S+TS+VLQSG
Sbjct 3282 YLSMFNKYKYYSGAMDTASYREASAAHLCKALQVYSETGSDVLFQPPNCSVTSSVLQSGL 3341
Query 3244 RKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSN 3303
KMA PSG VE CMVQVTCG+ TLNGLWLD+ V+CPRHV+C A+ + +PNY+ LL+ K+N
Sbjct 3342 VKMAAPSGVVENCMVQVTCGSMTLNGLWLDNYVWCPRHVMCPADQLSDPNYDALLVSKTN 3401
Query 3304 HSFLVQAG---NVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNG 3360
SF+VQ LRV+GH+M LL+L V+++NP+TP Y F ++PG +FSVLACYNG
Sbjct 3402 LSFIVQKNVGAPANLRVVGHTMVGTLLKLTVESANPQTPAYTFTTVKPGASFSVLACYNG 3461
Query 3361 SPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGK 3420
P+GV+ MR N TIKGSFL GSCGSVG+ + + ++FCYMH MEL G H G +G
Sbjct 3462 RPTGVFMVNMRQNSTIKGSFLCGSCGSVGYTQEGNVINFCYMHQMELSNGTHTGCAFDGV 3521
Query 3421 FYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE 3480
YG F DRQ Q +D T+N++AWLYAA++NG WF+ T + FN AM +
Sbjct 3522 MYGAFEDRQVHQVQLSDKYCTINIVAWLYAAILNGCNWFVKPNKTGIATFNEWAMSNQFT 3581
Query 3481 PLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQC 3540
+ L+ +TG++V + A++ L G G+TILG+++LEDEFTP DV Q
Sbjct 3582 EFIG--TQSVDMLAHKTGVSVEQLLYAIQTL-HKGFQGKTILGNSMLEDEFTPDDVNMQV 3638
Query 3541 SGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAA 3600
GV Q K+I G HW+ T L + + +Q T+++++ +++E L T ++ + A
Sbjct 3639 MGVVMQSGVKRISYGLVHWLFTTLLLAYVATLQLTKFTIWNYLFEVIPLQLTPLVLCVMA 3698
Query 3601 CAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPA----SWVMRIMTWLELADTSLSGYRL 3656
C ML VKHKH FL LFLLP+ + Y N+VY P S ++ + WL A +
Sbjct 3699 CVMLTVKHKHTFLTLFLLPTAICLTYANIVYEPQTPVSSALIAVANWLNPASVYMRTTH- 3757
Query 3657 KDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVIS 3716
D +Y S L ++ R +A+ L + + Y G+ ++ + +
Sbjct 3758 TDLGVYLSLCFALAVVVRRLYRPNASNLALALGSAMVWFYTYTTGDC-SSPLTYLMFLTT 3816
Query 3717 VTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCL 3776
+TS+Y+ V + +A+ V Y P ++ ++L+Y +GY C YFG+F L
Sbjct 3817 LTSDYTVTVFLAVNVAKFFARVVFLYAPHAGFIFPEVKLVLLMYLAVGYFCTVYFGVFSL 3876
Query 3777 LNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQ 3836
LN R+ LGVYDY VSTQEFRY+ GL P++S +A +LN+KL+GIGG PCIK+A+VQ
Sbjct 3877 LNLKLRVPLGVYDYTVSTQEFRYLTGNGLHAPRNSWEALRLNMKLIGIGGTPCIKIASVQ 3936
Query 3837 SKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLL 3896
SK++D+KCTSVVLLSVLQQL +E++SK WA CV+LHNDIL A D TEAF+ V L + L+
Sbjct 3937 SKLTDLKCTSVVLLSVLQQLHLEANSKAWAHCVKLHNDILAATDPTEAFDNFVCLFATLM 3996
Query 3897 SMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLK 3955
S VD+ L ++LD+ + LQA SEFS L SYA AQ +Y++A+ +GD S VLK
Sbjct 3997 SFSANVDLEALASDLLDHPSVLQATLSEFSHLASYAELEAAQSSYQKALNSGDASPQVLK 4056
Query 3956 KLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLR 4015
L+K++N+AK+ +++D A+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++
Sbjct 4057 ALQKAVNIAKNAYEKDKAVARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIK 4116
Query 4016 KLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEI 4075
KLDND LN +I+NAR+GCVPL+++PL + KL VV+PD + + +YA ALW+I
Sbjct 4117 KLDNDVLNGVISNARNGCVPLSVVPLCASNKLRVVIPDITIWNKVVTWPSLSYAGALWDI 4176
Query 4076 QQVVDADSKIVQLSEINMDNSPNLAWPLIVTALR-ANSAVKLQNNELSPVALRQMSCAAG 4134
+ + D ++V+ S++ N +L WPL++ R A+SAV LQNNE+ P L+ M +AG
Sbjct 4177 SLINNVDGEVVKSSDVTETN-ESLTWPLVLECTRAASSAVTLQNNEIRPSGLKTMVVSAG 4235
Query 4135 TTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVT 4194
C + ++LAYY +G + ++ +LS++ LKWA+ DG I EL+PPC+F+
Sbjct 4236 IDHANC-NTSSLAYYEPVEGRKMLMGILSENAHLKWAKVEGRDGFVNI--ELQPPCKFLI 4292
Query 4195 DTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPA 4254
PKGP+V+YLYF+K LNNL+RG +LG +AATVRLQAG+ TE NS+VLS F+VDP
Sbjct 4293 AGPKGPEVRYLYFVKNLNNLHRGQLLGHIAATVRLQAGSNTEFAINSSVLSAVTFSVDPG 4352
Query 4255 KAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHP 4314
KAY D++ +GG P+TNCVKML TGTG A++V PEAN DQ+++GGAS CLYCR HI+HP
Sbjct 4353 KAYLDFVNAGGAPLTNCVKMLTPKTGTGIAVSVKPEANADQDTYGGASVCLYCRAHIEHP 4412
Query 4315 NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADAS 4374
+ G C KGK+VQ+P DPVGF L+NT C VC W G+GC+CD LR + + S
Sbjct 4413 DVTGVCKFKGKFVQVPL-HIRDPVGFCLQNTPCNVCQFWIGHGCNCDALRGTTIPQSKDS 4471
Query 4375 TFLNR 4379
FLN
Sbjct 4472 NFLNE 4476
>sp|P0C6T4|R1A_BCHK4 Replicase polyprotein 1a OS=Bat coronavirus
HKU4 OX=694007 GN=1a PE=1 SV=1
Length=4434
Score = 4429 bits (11487), Expect = 0.0, Method: Composition-based stats.
Identities = 1481/4547 (33%), Positives = 2273/4547 (50%), Gaps = 313/4547 (7%)
Query 8 VNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEALSEAREHLK-NGTCGLVELE-KGV 60
NEK HV ++P+ D+ L F D E A ++ LK G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTDDMACKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMD--GIQYGRSG---ITLGVLVPHVGETP 115
+ L P V++ H +V +A D G R+ LG+ P+
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDQVGAAMMRTTLNAKPLGMFFPYDSSLE 139
Query 116 IAYRNVLLRKNGNKGAGGHSYGIDLKS---YDLGDELGTDPIEDYEQNWNTKHGSGALRE 172
LLRKNG G D K ++ D+L DP Y QN
Sbjct 140 TGEYTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LTRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAG--KSMCTLSEQLDYIESKRGVYC 230
L ++L GG +D CG +G P+ +A+ G + ++S R +
Sbjct 188 LLKKLIGGDCIP-IDQYMCGKNGKPIADYAKIVAKEGLTTLADIEVDVKSRMDSDRFI-V 245
Query 231 CRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQP-RVE 289
+ + W R + Y QT F I S + D K P+ F + S++ ++ P +
Sbjct 246 LNKKLYRVVWNVTRRNVPYPKQTAFTIVSVVQCDD-KDSVPEHTFTIGSQILMVSPLKAT 304
Query 290 KKKTEGFMGRI-RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTEN 348
K R+ + Y + Q+ ++ S + CN C +W T + ++ CG
Sbjct 305 NNKNFNLKQRLLYTFYGKDAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGANY 364
Query 349 LVIE-GPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGR--TRC 405
+ + G +P NA+ CP + HS A +N + + + GG+ T
Sbjct 365 SANDVDLQSSGLVPRNALFLANCPCANNGAC--SHSAAQVYNILDGKACVEVGGKSFTLT 422
Query 406 FGGCVFAYVGCYNKRAYWVPRASA-------DIGSGHTGITGDNVETLNEDLLEILSRER 458
FGG V+AY+GC + Y+VPRA + I +G TG VET N L + +
Sbjct 423 FGGVVYAYMGCCDGTMYFVPRAKSCVSRIGDAIFTGCTGTWDKVVETAN----LFLEKAQ 478
Query 459 VNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGN--YKVTKGKP 516
++N F L E V IL+ TS F + S++ + + N + VT G
Sbjct 479 RSLNFCQQFALTEVVLAILSGT---TSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDY 535
Query 517 VKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQ 576
++ A NIG +C A + + + + + + LD S
Sbjct 536 IRDAINIGAN-----GVCNATINAPFIAFTGLGESFKKVSAIPWKICSNLKSALDYYSSN 590
Query 577 SLRLV-------DAMVYTSDLLTNS---VIIMAYVTGGLVQQTSQWLSNLLGTTVEKLRP 626
+ V D + LL V +V L ++ L + L
Sbjct 591 IMFRVFPYDIPCDVSNFVELLLDCGKLTVATSYFVLRYLDEKFDTVLGTVSSACQTALSS 650
Query 627 IFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKAL 686
A A F+ D +++ K L+ ++ +++ V+ +D+++KA+
Sbjct 651 FLNACVAASRATAGFINDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDIMSKAM 710
Query 687 EMCIDQVTIAGAKLRSLNL--GEVFIAQSKGLYRQCIRGKE---QLQLLMPLKAPKEVTF 741
++ V+ AG KL ++ E + S + + K Q+ L++P K+
Sbjct 711 KLLHTNVSWAGTKLSAIIYEGREALLFNSGTYFCLSTKAKTLQGQMNLVLPGDYNKKTLG 770
Query 742 L-----EGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDK 796
+ D+ D S V + +G+LE P + IVG V V+ + + +D+
Sbjct 771 ILDPVPNADTIDVNANSTVVDVVHGQLE----PTNEHGPSMIVGNYVLVSDKLFVRTEDE 826
Query 797 EQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDERVDKVLNE 856
E Y + G + + +FRLKGG P K VTFG+ EV Y++V IT+++ +D +L+
Sbjct 827 EFYPLCTNGKVVS-TLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLSS 885
Query 857 -KCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEE 915
K + +TVE V +F V+ + V+ L P+ G D++++ Y+++ G+
Sbjct 886 SKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYVYNQDGDC 945
Query 916 NFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEE 975
+SS M S P ++ EE + E++ + + E DD + + + E V
Sbjct 946 AWSSNMTFSINPVEDVEEVEEFIEDDYLSD----ELPIADDEEA----WARAVEEVMP-- 995
Query 976 EEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVI 1035
D +EIE E +P E + + T V+ + S + +V
Sbjct 996 -------LDDILVAEIELEEDPPLETALESVEAEVVETAEAQEPSVESIDSTPSTSTVVG 1048
Query 1036 VNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHV 1095
N ++ +K VA E+DD ++L + VG
Sbjct 1049 EN--DLSVKPMSRVA-------------ETDDVLELETAV-VG----------------- 1075
Query 1096 VGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAV 1155
GP + + + + G+ + QV
Sbjct 1076 -GP----------VSDVTAIVTNDIVSVEQAQQCGVSSLPIQDEAS---ENQVHQVSDLQ 1121
Query 1156 NDKALYEQVVMDYLD---NLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACI 1212
++ L + ++ + +LKPR + K + + SV D
Sbjct 1122 GNELLCSETKVEIVQPRQDLKPR-RSRKSKVDLSKYKHTVINNSVTLVLGDAIQIASLLP 1180
Query 1213 DEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVIT---- 1268
+ L I G + S ++ E ++ + P VGD +
Sbjct 1181 KCILVNAANRH-----LKHGGGIAGVINKASGGDVQEESDEYISNNGPLHVGDSVLLKGH 1235
Query 1269 --SGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCK 1326
+ I VV P + +L R K +++ AG + K + +
Sbjct 1236 GLADAILHVVGPDARNNEDAALLKRCYKAF--NKHTIVVTPLISAGIFSVDPKVSFEYLL 1293
Query 1327 SAF-----------YVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIM 1375
+ + + A +K + L R + A+ IC + A +
Sbjct 1294 ANVTTTTYVVVNNEDIYNTLATPSKPDGLVYSFEGWRGTVRTAKNYGFTCFICTEYSANV 1353
Query 1376 ATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNL 1435
++ K + VD GV ++ Y++++ + +I N + + MP GYVTHG +L
Sbjct 1354 KFLRTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGCS-GICAMPFGYVTHGLDL 1411
Query 1436 EEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSY-SG 1494
++ +R +K P V ++S + + N + + +T E F+ V+ G Y W SG
Sbjct 1412 AQSGNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGGYHSWHLVSG 1469
Query 1495 QRTELGVEFLKR----GDKIVY-----HTLESPVEFHLDGEVLSLDKLKSLLSLREVK-- 1543
V + K G I Y + +++ V L+ ++ L+ R +
Sbjct 1470 DLIVKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFS----DLEACRAYLTSRAAQQV 1525
Query 1544 TIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDT 1603
I+V T+D N T +++ + T+ +Q G T+ G D++ P V G++ FV +
Sbjct 1526 NIEVLVTIDGVNFRTVILNDTTTFRKQLGATFYKGVDISDAFPTVKMGGESLFVADNLSE 1585
Query 1604 LRSEAF-EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQ 1662
EYY T D +FL RY S ++WKF G+ S+K ++ NCY+++ ++ +
Sbjct 1586 SEKVVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATIMMIDM 1645
Query 1663 L-EVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE-S 1720
L ++KF PALQ AY R + GD +F ALI+AY + T D + + LL A L S
Sbjct 1646 LHDIKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKAELTVS 1705
Query 1721 AKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESS 1780
AK V C CG + TG+ A +Y G S + L++ + CVCG + LV+ +
Sbjct 1706 AKMVWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLVEHSAP 1765
Query 1781 FVMMSAPPAEYKLQQG--TFLCANEYTG-NYQCGHYTHITAKETL-YRIDGAHLTKMSEY 1836
++++S + N + G GHY HI K+ L Y+ D LTK S+
Sbjct 1766 WLLVSGLNEVKVSTSTDPIYRAFNVFQGVETSVGHYVHIRVKDGLFYKYDSGSLTKTSDM 1825
Query 1837 KGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQP-IDLVPTQ 1895
K +T V+Y YT V Y LDGVT E+ P L YY KD YYT +P I P
Sbjct 1826 KCKMTSVWYPTVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKPTIKYSPAT 1885
Query 1896 PLPNASFDNFKLTCSNTKFADD-----LNQMTGF--TKPASRELSVTFFPDLNGDVVAID 1948
LP + + N L + D N + GF TKP S++L+ + P+ +GDV+ +
Sbjct 1886 ILPGSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNEDGDVLLSE 1945
Query 1949 YRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVE 2008
+ +Y+ +KKG L KPI+W N KPN LR L+ P+ N + VL
Sbjct 1946 FSNYNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDNKYTVLQDN 2005
Query 2009 DTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVK---TTEVVGNVILKPSDEGVKVTQ 2065
+Q E P ++V P +++IE K V GN GV V
Sbjct 2006 TSQ-----LVEHNVPVVDDV---PITTRKLIEVKCKGLNKPFVKGNFSFVNDPNGVTVVD 2057
Query 2066 ELGHEDLMAAYVE-NTSITIKKPNELSLALGLKTIATHGIAAI---NSVPWS-KILAYVK 2120
LG +L A YV+ NT + + N S L T+ + + + SV ++L
Sbjct 2058 TLGLTELRALYVDINTRYIVLRDNNWSSLFKLHTVESGDLQIVAAGGSVTRRARVLLGAS 2117
Query 2121 PFLGQAAITTSN----------------CAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTN 2164
A T + ++ +F L F K
Sbjct 2118 SLFASFAKITVTATTAACKTAGRGFCKFVVNYGVLQNMFVFLKMLFFLPFNYLWPKKQPT 2177
Query 2165 SRIRASLPTT---IAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMW------------ 2209
I S T + N VK + K + + +
Sbjct 2178 VDIGVSGLRTAGIVTTNIVKQCGTAAYYMLLGKFKRVDWKATLRLFLLLCTTILLLSSIY 2237
Query 2210 -LLLLSICLGSLICVTAAFGVLL------SNFGAPSYCNGVRELYLNSSNVTTMDFCEG- 2261
L+L + L S + + A G+L S G + C+G+ Y N+S M+FC
Sbjct 2238 HLVLFNQVLSSDVMLEDATGILAIYKEVRSYLGIRTLCDGLVVEYRNTS-FDVMEFCSNR 2296
Query 2262 SFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLS 2321
S C CL G DSL Y AL+ +Q I+SY L++ + A E+ LAY+L+T F +L L
Sbjct 2297 SVLCQWCLIGQDSLTRYSALQMLQTHITSYVLNIDWIWFALEFFLAYVLYTSSFNVLLLV 2356
Query 2322 AIMQVFFGYFAS--HFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMD 2379
Q FF Y ++ ++ + ++++ + +V P+ +VR+Y F A +++ K Y H+++
Sbjct 2357 VTAQYFFAYTSAFVNWRAYNYIVSGLFFLVTHIPLHGLVRVYNFLACLWFLRKFYSHVIN 2416
Query 2380 GCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGS 2439
GC + C++CYKRNR TRVE +TIV G KR+FY+ ANGG +C HNWNC+ CDT G+
Sbjct 2417 GCKDTACLLCYKRNRLTRVEASTIVCGTKRTFYIAANGGTSYCCKHNWNCVECDTAGVGN 2476
Query 2440 TFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFV 2499
TFI EVA DL+ +R I PTDQS Y VDSV VK+ + L++++ G YER+PL +F
Sbjct 2477 TFICTEVANDLTTTLRRLIKPTDQSHYYVDSVVVKDAVVELHYNRDGSSCYERYPLCYFT 2536
Query 2500 NLDNLR----ANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVS 2555
NL+ L+ G N +++D + E+ ++SA VYYSQ++C+P+LL+D LV+
Sbjct 2537 NLEKLKFKEVCKTPTGIPEHNFLIYDTNDRGQENLARSACVYYSQVLCKPMLLVDVNLVT 2596
Query 2556 DVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAAR 2615
VGDS E+++KM D+++++F + FSV +KL+ L+ TA + +G VL TF AAR
Sbjct 2597 TVGDSREIAIKMLDSFINSFISLFSVSRDKLEKLINTARDCVRRGDDFQNVLKTFTDAAR 2656
Query 2616 QGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNAR 2674
V++DV+T V++ L+ +H +D+++T + NN++ Y K +++ DLG ID A
Sbjct 2657 GHAGVESDVETTMVVDALQYAHKNDIQLTTECYNNYVPGYIKPDSINTLDLGCLIDLKAA 2716
Query 2675 HINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTK 2734
+N ++ N + +WN DYM LS+ ++QIR A +K NIPFRLT + R N+++ K
Sbjct 2717 SVNQTSMRNANGACVWNSGDYMKLSDSFKRQIRIACRKCNIPFRLTTSKLRAADNILSVK 2776
Query 2735 ISLKG--GKIVSTCF-------KLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIG 2785
S G S K TL A++ + +P ++++ + + I+
Sbjct 2777 FSATKIVGGAPSWLLRVRDLTVKGYCILTLFVFTVAVLSWFCLPSYSIATVNFNDDRILT 2836
Query 2786 YKAIQDGVTRDIISTDDCFANKHAGFDAWF-SQRGGSYKNDKSCPVVAAIITREIGFIVP 2844
YK I++G+ RDI D CFANK+ F WF GG Y+N CP+ A+I G V
Sbjct 2837 YKVIENGIVRDIAPNDVCFANKYGHFSKWFNENHGGVYRNSMDCPITIAVIAGVAGARVA 2896
Query 2845 GLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMG 2904
+P L + + F+ RVF+ N+C+TP I Y F+ S CVL++ECT+F+DA G
Sbjct 2897 NVPAN-LAWVGKQIVLFVSRVFANT-NVCFTPINEIPYDTFSDSGCVLSSECTLFRDAEG 2954
Query 2905 KPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRH 2963
P+CYD +L G+ SY++++P RY + D I+FP +E ++R+ T +YCR
Sbjct 2955 NLNPFCYDPTVLPGASSYADMKPHVRYDMYDSDMYIKFPEVIVESTLRITKTLATQYCRF 3014
Query 2964 GTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSAS 3023
G+CE S G+C+ST+G W L N++Y G++CG D +++ + L QPV +S S
Sbjct 3015 GSCEESAAGVCISTNGSWALYNQNYSTRPGIYCGDDYFDIVRRLAISLFQPVTYFQLSTS 3074
Query 3024 VVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYS 3083
+ G ++ + +T A YY K +R +Y + L++ LC + A L Y+
Sbjct 3075 LAMGLVLCVFLTAAFYYINKVKRALADYTQCAVVAVVAALLNSLCLCFIVANPLLVAPYT 3134
Query 3084 VFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRK--R 3141
Y Y TFY T + +F+ H+ W+ MF +VP W+ A Y + L+H W + +K
Sbjct 3135 AMYYYATFYLTGEPAFIMHISWYVMFGAVVPIWMLASYTVGVMLRHLFWVLAYFSKKHVD 3194
Query 3142 VMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTT 3201
V +G +F++AA F++ K+ Y+ LR+ + + RYL+L+NKYKY+SGA+DT
Sbjct 3195 VFTDGKLNCSFQDAASNIFVIGKDTYVALRNA--ITQDSFVRYLSLFNKYKYYSGAMDTA 3252
Query 3202 SYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVT 3261
SYREA HL KAL +S +G+D+LYQPP S+TS+VLQSG KM+ PSG VE C+VQVT
Sbjct 3253 SYREACAAHLCKALQTYSETGSDILYQPPNCSVTSSVLQSGLVKMSAPSGAVENCIVQVT 3312
Query 3262 CGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQ---AGNVQLRVI 3318
CG+ TLNGLWLD+TV+CPRH++C A+ + +PNY+ LLI K+NHSF+VQ LRV+
Sbjct 3313 CGSMTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVV 3372
Query 3319 GHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKG 3378
HSM LL+L VD +NP TP Y F ++PG +FSVLACYNG P+GV+ +R N TIKG
Sbjct 3373 AHSMVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKG 3432
Query 3379 SFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDT 3438
SFL GSCGSVG+ + ++F YMH MEL G H G+ +G YG F D+QT Q TD
Sbjct 3433 SFLCGSCGSVGYTENGGVINFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDK 3492
Query 3439 TITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTG 3498
T+NV+AWLYAAV+NG +WF+ + +N A+ + + L+ +TG
Sbjct 3493 YCTINVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVG--TQSIDMLAHRTG 3550
Query 3499 IAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHH 3558
++V M AA++ L G G+TILG + LEDEFTP DV Q GV Q K+I G H
Sbjct 3551 VSVEQMLAAIQSL-HAGFQGKTILGQSTLEDEFTPDDVNMQVMGVVMQSGVKRISYGFIH 3609
Query 3559 WMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLL 3618
W++ TF+ + + ++Q T+++++ +++E T ++ AC M VKHKH F+ LFLL
Sbjct 3610 WLISTFVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLLGFMACVMFTVKHKHTFMSLFLL 3669
Query 3619 PSLATVAYFNMVYMPA----SWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTA 3674
P + Y N+VY P S ++ + WL + D +Y S +L ++
Sbjct 3670 PVALCLTYANIVYEPQTLISSTLIAVANWLTPTSVYMRTTHF-DFGLYISLSFVLAIIVR 3728
Query 3675 RTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARA 3734
R + L + + Y G+ I+ + ++TS+Y+ V + LA+
Sbjct 3729 RLYRPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYTITVFATVNLAKF 3787
Query 3735 IVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVST 3794
I + Y P L ++ ++L+Y LGY C YFG+F LLN R+ LGVYDY VST
Sbjct 3788 ISGLVFFYAPHLGFILPEVKLVLLIYLGLGYMCTMYFGVFSLLNLKLRVPLGVYDYSVST 3847
Query 3795 QEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQ 3854
QEFR++ GL P++S +A LN KLLGIGG PCIKVATVQSK++D+KCTSVVLL+VLQ
Sbjct 3848 QEFRFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQSKLTDLKCTSVVLLTVLQ 3907
Query 3855 QLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDN 3914
QL +ES+SK W+ CV+LHN+IL A D TEAFE+ V L + L+S VD++ L ++ +N
Sbjct 3908 QLHLESNSKAWSYCVKLHNEILAAVDPTEAFERFVCLFATLMSFSANVDLDALANDLFEN 3967
Query 3915 RATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAA 3973
+ LQA +EFS L +YA TAQ +Y++A+ +GD S VLK L+K++NVAK+ +++D A
Sbjct 3968 SSVLQATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKA 4027
Query 3974 MQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGC 4033
+ RKLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GC
Sbjct 4028 VARKLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGC 4087
Query 4034 VPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINM 4093
VPL+I+PL + KL VV+PD + + + +YA +LW+I + + D+++V+ +++
Sbjct 4088 VPLSIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDITVINNVDNEVVKPTDVVE 4147
Query 4094 DNSPNLAWPLIVTALR-ANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNS 4152
N +L WPL++ R ++SAVKLQNNE+ P L+ M AG Q C + +A+AYY
Sbjct 4148 TN-ESLTWPLVIECSRSSSSAVKLQNNEIHPKGLKTMVITAGVDQVNC-NSSAVAYYEPV 4205
Query 4153 KGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLN 4212
+G R V+ LLS++ LKWA+ DG I EL+PPC+F+ PKGP+++YLYF+K LN
Sbjct 4206 QGHRMVMGLLSENAHLKWAKVEGKDGF--INIELQPPCKFLIAGPKGPEIRYLYFVKNLN 4263
Query 4213 NLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCV 4272
NL+RG +LG +AATVRLQAG TE +NSTVL+ AFAVDPAKAY DY+ SGG P++N V
Sbjct 4264 NLHRGQLLGHIAATVRLQAGANTEFASNSTVLTLVAFAVDPAKAYLDYVGSGGTPLSNYV 4323
Query 4273 KMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTT 4332
KML TGTG AI+V PEA DQE++GGAS CLYCR HI+HP+ G C K ++VQIP
Sbjct 4324 KMLAPKTGTGVAISVKPEATADQETYGGASVCLYCRAHIEHPDVSGVCKYKTRFVQIPA- 4382
Query 4333 CANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
DPVGF L+N C VC W GYGC+CD LR + + + FLN
Sbjct 4383 HVRDPVGFLLKNVPCNVCQYWVGYGCNCDALRNNTVPQSKDTNFLNE 4429
>sp|P0C6F7|R1A_BC133 Replicase polyprotein 1a OS=Bat coronavirus
133/2005 OX=389230 GN=1a PE=3 SV=1
Length=4441
Score = 4422 bits (11469), Expect = 0.0, Method: Composition-based stats.
Identities = 1464/4544 (32%), Positives = 2257/4544 (50%), Gaps = 300/4544 (7%)
Query 8 VNEKT--HVQLSLPVLQVRDV---LVRGFGDSVEEALSEAREHLK-NGTCGLVELE-KGV 60
NEK HV ++P+ D+ L F D E A ++ LK G V + +
Sbjct 21 YNEKRSDHVACTVPLCDTEDMASKLTPWFEDG-ETAFNQVSSILKEKGKILFVPMHMQRA 79
Query 61 LPQLEQPYVFIKRSDALSTNHGHKVVELVAEMD--GIQYGRSG---ITLGVLVPHVGETP 115
+ L P V++ H +V +A D G R+ LG+ P+
Sbjct 80 MKFLPGPRVYLVERLTGGMLSKHFLVNQLAYKDHVGAAMMRTTLNVKPLGMFFPYDSSLE 139
Query 116 IAYRNVLLRKNGNKGAGGHSYGIDLKS---YDLGDELGTDPIEDYEQNWNTKHGSGALRE 172
LLRKNG G D K ++ D+L DP Y QN
Sbjct 140 TGEHTFLLRKNGLGGQLFRERPWDRKETPYVEILDDLEADPTGKYSQN------------ 187
Query 173 LTRELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAG--KSMCTLSEQLDYIESKRGVYC 230
L ++L GG VD CG +G P+ +A+ G + ++S R +
Sbjct 188 LLKKLIGGDCIP-VDQYMCGKNGKPIADYAKIVAKEGLTTLADIEVDVKSRMDSDRFI-V 245
Query 231 CRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQP-RVE 289
+ + W R + Y QT F + S + D K P+ F + S++ ++ P +
Sbjct 246 LNKKLYRVVWNVTRRNVPYSKQTAFTVVSVIQCDD-KESVPEHTFTIGSQILMVSPLKAT 304
Query 290 KKKTEGFMGRI-RSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTEN 348
K R+ + Y + Q+ ++ S + CN C +W T + ++ CG
Sbjct 305 NNKNFNLKQRLLHTFYGKEAVQQPGYIYHSAYVDCNACGRGTWCTGNAIQGFACDCGANY 364
Query 349 LVIE-GPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGR--TRC 405
+ + G +P NA+ CP + H+ A ++ + + + GG+ T
Sbjct 365 SANDVDLQSSGLVPKNALFLANCPCANNGAC--SHNAAQVYSILDGKACVEVGGKSFTLT 422
Query 406 FGGCVFAYVGCYNKRAYWVPRASA-------DIGSGHTGITGDNVETLNEDLLEILSRER 458
FGG V+AY+GC + Y+VPRA + I +G TG VET N L + +
Sbjct 423 FGGVVYAYMGCCDGTMYFVPRAKSCVSRIGDAIFTGCTGTWDKVVETAN----LFLEKAQ 478
Query 459 VNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGN--YKVTKGKP 516
++N F L E V IL+ TS F + S++ + + N + VT G
Sbjct 479 HSLNFCQQFALTEVVLAILSGT---TSTFEELRDLCHNASYEKVRDHLVNHGFVVTIGDY 535
Query 517 VKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQ 576
++ A NIG +C A + + + + + LD
Sbjct 536 IRDAINIGAN-----GVCNATINAPFIAFTGLGESFKKVAAIPWKICSNLKSALDYYCSN 590
Query 577 SLRLV-------DAMVYTSDLLTNS---VIIMAYVTGGLVQQTSQWLSNLLGTTVEKLRP 626
+ V D + LL V +V L ++ L + L
Sbjct 591 IMFRVFPYDIPCDVNDFVELLLDCGKLTVATSYFVLRYLDEKFDTVLGTVSNACQTALSS 650
Query 627 IFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKAL 686
A A F+ D +++ K L+ ++ +++ V+ +D+++KA+
Sbjct 651 FLNACVAASRATAGFISDMFKLFKVLMHKLYVYTSCGYVAVAEHSSKIVQQVLDIMSKAM 710
Query 687 EMCIDQVTIAGAKLRSLNL--GEVFIAQSKGLYRQCIRGK---EQLQLLMPLKAPKEVTF 741
++ V+ AG KL ++ E + S + + K +Q+ L++P K+
Sbjct 711 KLLHTNVSWAGTKLSAIIYEGREALLFNSGTYFCLSTKAKTLQDQMNLVLPGDYNKKTLG 770
Query 742 L-----EGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDK 796
+ D+ D S V + +G+LE P + IVG V V+ + + D+
Sbjct 771 ILDPVPNADTIDVTANSTVVDVVHGQLE----PTNEHGPSMIVGNYVLVSDKLFVRTDDE 826
Query 797 EQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDERVDKVLNE 856
E Y G + + +FRLKGG P K VTFG+ EV Y++V IT+++ +D +L+
Sbjct 827 EFYPLCINGKVVS-TLFRLKGGMPSKKVTFGDVNTVEVTAYRSVSITYDIHPVLDALLSS 885
Query 857 -KCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEE 915
K + +TVE V +F V+ + V+ L P+ G D++++ Y+++ G+
Sbjct 886 SKLATFTVEKDLLVEDFVDVIKDEVLTLLTPLLRGYDIDGFDVEDFIDVPCYVYNQDGDC 945
Query 916 NFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEE 975
+SS M S P ++ EE + E++ + + E DD + + + E V +
Sbjct 946 AWSSNMTFSINPVEDVEEVEEFIEDDYLSD----ELPIADDEEA----WTRAVEEVMPLD 997
Query 976 EEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVI 1035
+ ++ E +E E E + L + + + + + + +
Sbjct 998 DILVAEIELE-EDLPLETALESVEAEVGESISDELCVVETAKAQEPSVESTDSTPSTSTV 1056
Query 1036 VNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHV 1095
V+ ++ +K VA G + + V
Sbjct 1057 VSENDLSVKPMSRVA-------------------------ETGDVLEVETAVVGGPVSDV 1091
Query 1096 VGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAV 1155
+ DI ++ A + G+ + V +
Sbjct 1092 TASVVT--NDIVSVEQAQQ--------------CGVSSLPIQD--EASENQVHQVPDLQC 1133
Query 1156 NDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEV 1215
+ E ++ +L+PR K + + SV D V
Sbjct 1134 TSETKVE--IVQPRQDLRPR-RLRKSKVDLSKYKHTVINNSVTLVLGDAIQIASLLPKCV 1190
Query 1216 TTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVIT------S 1269
L I G + S ++ E ++ P VGD + +
Sbjct 1191 LVNAANRH-----LKHGGGIAGAINKASGGDVQEESDEYISNSGPLHVGDSVLLKGYGLA 1245
Query 1270 GDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAF 1329
I VV P + +L R K +++ +G + K + + +
Sbjct 1246 DAILRVVGPDARNNEDAALLKRCYKTF--NKHTIVVTPLISSGIFSVDPKVSFEYLLANV 1303
Query 1330 -----------YVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATI 1378
+ + A +K + L R + A+ IC + A + +
Sbjct 1304 TTTTYVVVNNEDIYNTLATPSKPDGLVYSFEGWRGTVRTAKNYGFTCFICTEYSANVKFL 1363
Query 1379 QRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEA 1438
+ K + VD GV ++ Y++++ + +I N + MP GYVTHG +L ++
Sbjct 1364 RTKGVDTTKKIQTVD-GVSYYLYSARDALTDVIAAANGCP-GICAMPFGYVTHGLDLAQS 1421
Query 1439 ARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSY-SGQRT 1497
+R +K P V ++S + + N + + +T E F+ V+ G Y W SG
Sbjct 1422 GNYVRQVKVPYVCLLASKEQIPIMNSDV--AIQTPETAFINNVTSNGGYHSWHLVSGDLI 1479
Query 1498 ELGVEFLKR----GDKIVY-----HTLESPVEFHLDGEVLSLDKLKSLLSLREVK--TIK 1546
V + K G I Y + +++ V L+ ++ L+ R + I+
Sbjct 1480 VKDVCYKKLLHWSGQTICYADNKFYVVKNDVALPFS----DLEACRAYLTSRAAQQVNIE 1535
Query 1547 VFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDD-TLR 1605
V T+D N T +++ + T+ +Q G T+ G D++ P V G++ FV + +
Sbjct 1536 VLVTIDGVNFRTVILNDATTFRKQLGATFYKGVDISDALPTVKMGGESLFVADNLSESEE 1595
Query 1606 SEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQL-E 1664
EYY T D +FL RY S ++WKF G+ S+K ++ NCY+++ ++ + L +
Sbjct 1596 VVLKEYYGTSDVTFLQRYYSLQPLVQQWKFVVHDGVKSLKLSNYNCYINATIMMIDMLHD 1655
Query 1665 VKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE-SAKR 1723
+KF PALQ AY R + GD +F ALI+AY + T D + + LL A L SAK
Sbjct 1656 IKFVVPALQNAYLRYKGGDPYDFLALIMAYGDCTFDNPDDEAKLLHTLLAKAELTVSAKM 1715
Query 1724 VLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVM 1783
V C CG + TG+ A +Y G S + L++ + CVCG + LV+ + +++
Sbjct 1716 VWREWCTVCGIRDIEYTGMRACVYAGVNSMEELQSVFNETCVCGSVKHRQLVEHSTPWLL 1775
Query 1784 MSAPPAEYKLQQG--TFLCANEYTG-NYQCGHYTHITAKETL-YRIDGAHLTKMSEYKGP 1839
+S + N + G GHY H+ K+ L Y+ D LTK S+ K
Sbjct 1776 VSGLNEVKVSTSTDPVYRAFNVFQGVETSVGHYVHVRVKDGLFYKYDSGSLTKTSDMKCK 1835
Query 1840 VTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQP-IDLVPTQPLP 1898
+T V+Y + YT V Y LDGVT E+ P L YY KD YYT +P I P LP
Sbjct 1836 MTSVWYPKVRYTADCNVVVYDLDGVTKVEVNPDLSNYYMKDGKYYTSKPTIKYSPATILP 1895
Query 1899 NASFDNFKLTCSNTKFADD-----LNQMTGF--TKPASRELSVTFFPDLNGDVVAIDYRH 1951
+ + N L + D N + GF TKP S++L+ + P+ +GDV+ ++ +
Sbjct 1896 GSVYSNSCLVGVDGTPGSDTISKFFNDLLGFDETKPISKKLTYSLLPNEDGDVLLSEFNN 1955
Query 1952 YSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQ 2011
Y+ +KKG L KPI+W N KPN LR L+ P+ N + VL +Q
Sbjct 1956 YNPVYKKGVMLKGKPILWVNNGVCDSALNKPNRASLRQLYDVAPIVLDNKYTVLQDNTSQ 2015
Query 2012 GMDNLACESQQPTSEEVVENPTIQKEVIECDVK---TTEVVGNVILKPSDEGVKVTQELG 2068
+ E P E+V +++IE K V GN GV V LG
Sbjct 2016 LI-----EPNVPVVEDVS---ITTRKLIEVKCKGLNKPFVKGNFSFVNDPNGVTVVDTLG 2067
Query 2069 HEDLMAAYVE-NTSITIKKPNELSLALGLKTIATHGIAAI---NSVPWS-KILAYVKPFL 2123
+L A YV+ NT + + N S L T+ + + + SV ++L
Sbjct 2068 LTELRALYVDINTRYIVLRDNNWSSLFKLHTVESGDLQIVANGGSVTRRARVLLGASSLF 2127
Query 2124 GQAAITTSNCAKRLAQRVFNNYMPYVFTL----------------LFQLCTFTKSTNSRI 2167
A T + ++ +V F K +
Sbjct 2128 ASFAKITVTATTAACKTAGRSFCKFVVNYGVLQNMFLFLKMLFFLPFNYLWPKKQPTVDV 2187
Query 2168 RASLPTT---IAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVT 2224
S T + N VK + K + + + L + L S+ +
Sbjct 2188 GVSGLRTAGVVTTNIVKQCGTAAYYMLLGKFKRVDWKATLRLFLLLCTTILLLSSIYHLV 2247
Query 2225 AAFGVLLSN-------------------FGAPSYCNGVRELYLNSSNVTTMDFCEG-SFP 2264
VL S+ G + C+G+ Y N+S +DFC S
Sbjct 2248 IFNQVLSSDVMLEDATGILAMYKEVRSYLGIRTLCDGLAVEYRNTS-FDVVDFCSNRSVL 2306
Query 2265 CSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIM 2324
C CL G DSL Y AL+ +Q I+SY L++ + A E+ LAY+L+T F +L L
Sbjct 2307 CQWCLIGQDSLTRYSALQMLQTHITSYVLNIDWIWFALEFFLAYVLYTSSFNVLLLVVTA 2366
Query 2325 QVFFGYFAS--HFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCT 2382
Q FF Y ++ ++ + ++++ + +V P+ +VR+Y F A +++ K Y H+++GC
Sbjct 2367 QYFFAYTSAFVNWRAYNYIVSGLFFLVTHIPLHGLVRVYNFLACLWFLRKFYSHVINGCK 2426
Query 2383 SSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFI 2442
+ C++CYKRNR TRVE +TIV G KR+FY+ ANGG +C HNWNC+ CDT G+TFI
Sbjct 2427 DTACLLCYKRNRLTRVEASTIVCGTKRTFYIAANGGTSYCCKHNWNCVECDTAGVGNTFI 2486
Query 2443 SDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLD 2502
EVA DL+ +R I PTDQS Y VDSV VK+ + L++++ G YER+PL +F NL+
Sbjct 2487 CTEVANDLTTTLRRLIKPTDQSHYYVDSVVVKDAVVELHYNRDGSSCYERYPLCYFTNLE 2546
Query 2503 NLR----ANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVG 2558
L+ G N +++D + E+ ++SA VYYSQ++C+P+LL+D LV+ VG
Sbjct 2547 KLKFKEVCKTPTGIPEHNFLIYDTNDRGQENLARSACVYYSQVLCKPMLLVDVNLVTTVG 2606
Query 2559 DSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGV 2618
DS E+++KM D+++++F + FSV +KL+ L+ TA + +G VL TF AAR
Sbjct 2607 DSREIAIKMLDSFINSFISLFSVSRDKLEKLINTARDCVRRGDDFQTVLKTFTDAARGHA 2666
Query 2619 -VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHIN 2677
V++DV+T V++ L+ +H +D+++T + NN++ Y K +++ DLG ID A +N
Sbjct 2667 GVESDVETTMVVDALQYAHKNDIQLTTECYNNYVPGYIKPDSINTLDLGCLIDLKAASVN 2726
Query 2678 AQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISL 2737
++ N + +WN DYM LS+ ++QIR A +K NIPFRLT + R N+++ K S
Sbjct 2727 QTSMRNANGACVWNSGDYMKLSDSFKRQIRIACRKCNIPFRLTTSKLRAADNILSVKFSA 2786
Query 2738 KG--GKIVSTCF-------KLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKA 2788
G S K TL A++ + +P ++++ + + I+ YK
Sbjct 2787 TKIVGGAPSWLLRVRDLTVKGYCILTLFVFTVAVLSWFCLPSYSIATVNFNDDRILTYKV 2846
Query 2789 IQDGVTRDIISTDDCFANKHAGFDAWF-SQRGGSYKNDKSCPVVAAIITREIGFIVPGLP 2847
I++G+ RDI D CFANK+ F WF GG Y+N CP+ A+I G V +P
Sbjct 2847 IENGIVRDIAPNDACFANKYGHFSKWFNENHGGVYRNSVDCPITIAVIAGVAGARVANVP 2906
Query 2848 GTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPV 2907
T L + + F+ RVF+ N+C+TP+ I Y F+ S CVL++ECT+F+DA G
Sbjct 2907 AT-LAWVGRQIVLFVSRVFANT-NVCFTPTNEIPYDTFSDSGCVLSSECTLFRDAEGNLN 2964
Query 2908 PYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRHGTC 2966
P+CYD +L G+ SY++++P RY + D I+FP E ++R+ T +YCR G+C
Sbjct 2965 PFCYDPTVLPGASSYADMKPHVRYDMYDSDMYIKFPEVIFESTLRITKTLATQYCRFGSC 3024
Query 2967 ERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVA 3026
E S G+C+ST+G W L N++Y G++CG D +++ + L QPV +S S+
Sbjct 3025 EESAAGVCISTNGSWALYNQNYSTRPGIYCGDDYFDIVRRLAVSLFQPVTYFQLSTSLAM 3084
Query 3027 GGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFY 3086
G ++ + +T A YY K +R +Y + L++ LC + A L Y+ Y
Sbjct 3085 GLVLCVFLTAAFYYINKVKRALADYTQCAVVAVVAALLNSLCLCFIVANPLLVAPYTAMY 3144
Query 3087 LYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRK--RVMF 3144
Y TFY T + +F+ H+ W+ MF +VP W+ A Y + L+H W + +K V
Sbjct 3145 YYATFYLTGEPAFIMHISWYVMFGTVVPIWMLASYTVGVMLRHLFWVLAYFSKKHVDVFT 3204
Query 3145 NGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYR 3204
+G +F++AA F++ K+ Y+ LR+ + + RYL+L+NKYKY+SGA+DT SYR
Sbjct 3205 DGKLNCSFQDAASNIFVIGKDTYVALRNA--ITQDSFVRYLSLFNKYKYYSGAMDTASYR 3262
Query 3205 EAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGT 3264
EA HL KAL +S +G+D+LYQPP S+TS+VLQSG KM+ PSG VE C+VQVTCG+
Sbjct 3263 EACAAHLCKALQTYSETGSDILYQPPNCSVTSSVLQSGLVKMSAPSGAVENCIVQVTCGS 3322
Query 3265 TTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQ---AGNVQLRVIGHS 3321
TLNGLWLD+TV+CPRH++C A+ + +PNY+ LLI K+NHSF+VQ LRV+ HS
Sbjct 3323 MTLNGLWLDNTVWCPRHIMCPADQLTDPNYDALLISKTNHSFIVQKHIGAQANLRVVAHS 3382
Query 3322 MQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFL 3381
M LL+L VD +NP TP Y F ++PG +FSVLACYNG P+GV+ +R N TIKGSFL
Sbjct 3383 MVGVLLKLTVDVANPSTPAYTFSTVKPGASFSVLACYNGKPTGVFTVNLRHNSTIKGSFL 3442
Query 3382 NGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTIT 3441
GSCGSVG+ + ++F YMH MEL G H G+ +G YG F D+QT Q TD T
Sbjct 3443 CGSCGSVGYTENGGVLNFVYMHQMELSNGTHTGSSFDGVMYGAFEDKQTHQLQLTDKYCT 3502
Query 3442 LNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAV 3501
+NV+AWLYAAV+NG +WF+ + +N A+ + + L+ +TG++V
Sbjct 3503 INVVAWLYAAVLNGCKWFVKPTRVGIVTYNEWALSNQFTEFVG--TQSIDMLAHRTGVSV 3560
Query 3502 LDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWML 3561
M AA++ L G G+TILG + LEDEFTP DV Q GV Q K+I G HW++
Sbjct 3561 EQMLAAIQSL-HAGFQGKTILGQSTLEDEFTPDDVNMQVMGVVMQSGVKRISYGFMHWLM 3619
Query 3562 LTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSL 3621
T + + + ++Q T+++++ +++E T + AC M VKHKH FL LFLLP
Sbjct 3620 STLVLAYVSVMQLTKFTMWTYLFETIPTQMTPLLFGFMACVMFTVKHKHTFLSLFLLPVA 3679
Query 3622 ATVAYFNMVYMPASWV----MRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTV 3677
+ Y N+VY P + V + + WL + L D +Y S +L ++ R
Sbjct 3680 LCLTYANIVYEPQTLVSSTLIAVANWLTPTSVYMRTTHL-DFGLYISLSFVLAIIVRRLY 3738
Query 3678 YDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVF 3737
+ L + + Y G+ I+ + ++TS+Y+ V + LA+ I
Sbjct 3739 RPSMSNLALALCSGVMWFYTYVIGDH-SSPITYLMFITTLTSDYTITVFATVNLAKFISG 3797
Query 3738 VCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEF 3797
+ Y P L ++ ++L+Y LGY C YFG+F LLN R+ LGVYDY VSTQEF
Sbjct 3798 LVFLYAPHLGFILPEVKLVLLIYLCLGYMCTMYFGVFSLLNLKLRVPLGVYDYSVSTQEF 3857
Query 3798 RYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLR 3857
R++ GL P++S +A LN KLLGIGG PCIKVATVQSK++D+KCTSVVLL+VLQQL
Sbjct 3858 RFLTGNGLHAPRNSWEALILNFKLLGIGGTPCIKVATVQSKLTDLKCTSVVLLTVLQQLH 3917
Query 3858 VESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRAT 3917
+ES+SK W+ CV+LHN+IL A D TEAFE+ V L + L+S VD++ L ++ +N +
Sbjct 3918 LESNSKAWSYCVKLHNEILAAVDPTEAFERFVCLFATLMSFSANVDLDALANDLFENSSV 3977
Query 3918 LQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQR 3976
LQA +EFS L +YA TAQ +Y++A+ +GD S VLK L+K++NVAK+ +++D A+ R
Sbjct 3978 LQATLTEFSHLATYAELETAQSSYQKALNSGDASPQVLKALQKAVNVAKNAYEKDKAVAR 4037
Query 3977 KLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPL 4036
KLE+MA+QAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN +I NAR+GCVPL
Sbjct 4038 KLERMAEQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGVIANARNGCVPL 4097
Query 4037 NIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNS 4096
+I+PL + KL VV+PD + + + +YA +LW++ + + D+++V+ +++ N
Sbjct 4098 SIVPLCASNKLRVVIPDISVWNKVVNWPSVSYAGSLWDVTVINNVDNEVVKPTDVVETN- 4156
Query 4097 PNLAWPLIVTALRA-NSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGG 4155
+L WPL++ RA +SAVKLQNNE+ P L+ M AG Q C+ +A+AYY +G
Sbjct 4157 ESLTWPLVIECSRASSSAVKLQNNEIHPKGLKTMVVTAGIDQVNCS-SSAVAYYEPVQGH 4215
Query 4156 RFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLN 4215
R V+ LLS++ LKWA+ DG I EL+PPC+F+ PKGP+++YLYF+K LNNL+
Sbjct 4216 RMVMGLLSENAHLKWAKVEGKDGF--INIELQPPCKFLIAGPKGPEIRYLYFVKNLNNLH 4273
Query 4216 RGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKML 4275
RG +LG +AATVRLQAG TE +NSTVL+ AFAVDPAKAY DY+ SGG P++N VKML
Sbjct 4274 RGQLLGHIAATVRLQAGANTEFASNSTVLTLVAFAVDPAKAYLDYVGSGGTPLSNYVKML 4333
Query 4276 CTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCAN 4335
TGTG AI+V PEA DQE++GGAS CLYCR HI+HP+ G C K ++VQIP
Sbjct 4334 APKTGTGVAISVKPEATADQETYGGASVCLYCRAHIEHPDVSGVCKYKTRFVQIPA-HVR 4392
Query 4336 DPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
DPVGF L+N C VC W GYGC+CD LR + + + FLN
Sbjct 4393 DPVGFLLKNVPCNVCQYWVGYGCNCDALRNNTVPQSKDTNFLNE 4436
>sp|P0C6T6|R1A_BCHK9 Replicase polyprotein 1a OS=Bat coronavirus
HKU9 OX=694006 GN=1a PE=3 SV=1
Length=4248
Score = 4372 bits (11339), Expect = 0.0, Method: Composition-based stats.
Identities = 1584/4454 (36%), Positives = 2364/4454 (53%), Gaps = 342/4454 (8%)
Query 28 VRGFGDSVEEALSEAREHLKNGTCGLVELEKGV--LPQLEQPYVFIKRSDALSTNHG-HK 84
V G+ +EEAL A++ L+ LV + + P + V I S +TN G
Sbjct 29 VTGWDIPIEEALEYAKQQLRTPEPQLVFVPYYLSHAPGISGDRVVITDSIWYATNFGWQP 88
Query 85 VVELVAEMDGIQYGRSGITLGVLVPHVGETPIAYR-NVLLRKNGNKGAGGHSYGIDLKSY 143
+ EL + DG++YGR G T GVL+P + I ++ +RK G G +S L +
Sbjct 89 IRELAMDKDGVRYGRGG-THGVLLPMQDPSFIMGDIDIQIRK---YGIGANSPPDVLPLW 144
Query 144 DLGDELGTD--PIEDYEQNW---NTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPL 198
D + G D P D+ N K G L+ + DNN G +
Sbjct 145 DGFSDPGPDVGPYLDFPDNCCPTKPKAKRGGDVYLSDQYG-------FDNN-----GILV 192
Query 199 DCIKDFLARAGKSMCTLSEQLDYIESKRGV--YCCRDHEHEIAWFTERSDKSYEHQTPFE 256
+ + L KS TL + L + R Y D ++A R Q+ F
Sbjct 193 EPVMKLLGVI-KSDFTLEQLLAALGKYRTEDGYDLPDGYVKVAIKVGRKAVPVLKQSIFT 251
Query 257 IKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGR-IRSVYPVASPQECNNM 315
+ + P + +P ++ V K G +G+ + +V + S NN
Sbjct 252 VVGVT-----EQLVPGYYYPFSTSSVVEH---TKPTRGGPVGKTVEAV--MLSLYGTNNY 301
Query 316 HLST---LMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYLPTNAVVKMPCPA 372
+ +T +KC++CD W + CG E + ++C + V+K C
Sbjct 302 NPATPVARLKCSYCDYYGWTPLKDIGTVNCLCGAE---FQLTSSCVDAESAGVIKPGCVM 358
Query 373 CQDPEIGPEHSVADYHNHSNIETRLRKGGRTRC-FGGCVFAYVGCYNKRAYWVPRASADI 431
D G RL G RT FGG +++ +G N WVPRA + +
Sbjct 359 LLDKSPG---------------MRLIPGNRTYVSFGGAIWSPIGKVNGVTVWVPRAYSIV 403
Query 432 GSGHTGITGD-NVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSA-FID 489
H+G G + +N++L+E L I + D N A +A+ T A +
Sbjct 404 AGEHSGAVGSGDTVAINKELVEYLIE---GIRVDADTLDNPTCATFIANLDCDTKAPVVH 460
Query 490 TIKSLDYKSFKTIVESCGNYKVTKG-KPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIF 548
T++SL C K+ G KP+ + + L + Q A ++
Sbjct 461 TVESLQ--------GLCLANKIMLGDKPLP----TDEFHPFIVGL-AYHVQRACWYGALA 507
Query 549 ARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY-VTGGLVQ 607
+RT +A D R + ++ VY + + AY V +
Sbjct 508 SRTFEA----FRDFVRTEEERFAQFFGKVCAPINGCVYLAYTTGRVTLFSAYQVLNTAIA 563
Query 608 QTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVA 667
++ + V+ L+PI EW+ K+S E L L F +VKG+ Q
Sbjct 564 KSKDAFGGVAAIVVDMLKPILEWVLKKMSIAKGAWLPYAEGLLALFKAQFTVVKGKFQFL 623
Query 668 SDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQCIRGKEQL 727
++ D++ + + V AG K+ +L G + KG+ + ++L
Sbjct 624 RASLNSKCHSLCDLLTTIMSKLLTSVKWAGCKVDALYTGTYYYFSRKGVLTEVQLCAKRL 683
Query 728 QLLM-PLKAPKEVTFLEGDSH-DTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCV 785
LL+ P + EV L+GD LT E+ G LE + D + GT V +
Sbjct 684 GLLLTPKQQKMEVEVLDGDFDAPVTLTDLELEECTGVLEEVFGASDV---KLVKGTLVSL 740
Query 786 NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFE 845
+ + +D Y + G FRL+GG + VTFG++ V + V +++
Sbjct 741 ASKLFVRTEDGFLYRYVKSG-GVLGKAFRLRGGG-VSKVTFGDEEVHTIPNTVTVNFSYD 798
Query 846 LDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTN-----MGIDLDE 900
+ E +D +L++ + + VE GT++ + ACVV +AV + L DL ++ I+L++
Sbjct 799 VCEGLDAILDKVMAPFQVEEGTKLEDLACVVQKAVYERLS---DLFSDCPAELRPINLED 855
Query 901 WSVATFYLFDDAGEENFSSRMYCSF---YPPDEEEEDDAECEEEEIDETCEHEYGTEDDY 957
+ + +++ E+ MY S P D+E DD I++T E ++D +
Sbjct 856 FLTSECFVYSKDYEKILMPEMYFSLEDAVPVDDEMVDD-------IEDTVEQASDSDDQW 908
Query 958 QGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVA 1017
G +E + D+T + ++ GY K+ ++V
Sbjct 909 LG----------------DEGAEDCDNTIQDVDVATSMTTPC--------GYTKIAEHVY 944
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
IKC DIV+EA++ + V+VNAAN++L HGGGVAGALN+ATN AMQKES +YIK NG L
Sbjct 945 IKCADIVQEARNYSYAVLVNAANVNLHHGGGVAGALNRATNNAMQKESSEYIKANGSLQP 1004
Query 1078 GGSCLLSGHNLAKK-CLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKP 1136
GG LLS H LA LHVVGP+ G+D+ LL A Y + D +L PL+SAGIFG
Sbjct 1005 GGHVLLSSHGLASHGILHVVGPDKRLGQDLALLDAVYAAYTGFDSVLTPLVSAGIFGFTV 1064
Query 1137 LQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKS 1196
+SL V+ V Y+ V D+ LYE+ + D P+ E + +E
Sbjct 1065 EESLCSLVKNVACTTYVVVYDRQLYERALATSFDVPGPQSSVQHVPAIDWAEAVEVQESI 1124
Query 1197 VVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLE 1256
V Q + + L ET ++ + + D ++ +R
Sbjct 1125 VDQVETPSLGAVDTVDSNADSGLNETARSPENVV--GSVPDDVVADVESCVRD------- 1175
Query 1257 KDAPYMVGDVITSGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLE 1316
++ + +KKV D+ Q T+E
Sbjct 1176 -------------------------------LVRQVVKKVKRDKRPPPIVPQ----QTVE 1200
Query 1317 EAKTALKKCKSAFYVLPSEAPNA---KEEILGTVSWNLREMLAHAEETRKLMPICMDVRA 1373
+ P E + ++ VS + M+ +E L+P+ +D A
Sbjct 1201 QQ--------------PQEISSPGDCNTVLVDVVSMSFSAMVNFGKEKGLLIPVVIDYPA 1246
Query 1374 IMATIQRKYKGIKIQEGIVDY-GVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHG 1432
+ ++R +EG+ G F+ Y+ +P+ + LNSL PL+ +P G++ +G
Sbjct 1247 FLKVLKR----FSPKEGLFSSNGYEFYGYSRDKPLHEVSKDLNSLGRPLIMIPFGFIVNG 1302
Query 1433 FNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLT---SSSKTSEEHFVETVSLAGSYRD 1489
L +A MR L P V V S +V Y Y S T+ + FV + L G+ RD
Sbjct 1303 QTLAVSAVSMRGLTVPHTVVVPSESSVPLYRAYFNGVFSGDTTAVQDFVVDILLNGA-RD 1361
Query 1490 WSYSGQRTELGVE------FLKRGDKIVYHTLESPVEFHLDGEVL----SLDKLKSLLSL 1539
W +T V+ KRG+ Y + + + G+V+ ++ K ++ L
Sbjct 1362 WDV--LQTTCTVDRKVYKTICKRGN--TYLCFDDTNLYAITGDVVLKFATVSKARAYLET 1417
Query 1540 REVKT---IKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFF 1596
+ IKV TTVD N T LV + +Y Q G + DG D + P EG +
Sbjct 1418 KLCAPEPLIKVLTTVDGINYSTVLVSTAQSYRAQIGTVFCDGHDWSNKNPMPTDEGTHLY 1477
Query 1597 VLPSDDTLRSEAF-EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSS 1655
+ + A EYY D + + R MS + W + V G + D+NCYL+
Sbjct 1478 KQDNFSSAEVTAIREYYGVDDSNIIARAMSIRKTVQTWPYTVVDGRVLLAQRDSNCYLNV 1537
Query 1656 VLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQH 1715
+ LQ ++V F+ P + AY + G+ +++A T G D ++ +L H
Sbjct 1538 AISLLQDIDVSFSTPWVCRAYDALKGGNPLPMAEVLIALGKATPGVSDDAHMVLSAVLNH 1597
Query 1716 ANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLV 1775
+ +A+RV+ VC+HCG TG +A + G++ D+L VS+ C CGR A +Y+
Sbjct 1598 GTV-TARRVMQTVCEHCGVSQMVFTGTDACTFYGSVVLDDLYAPVSVVCQCGRPAIRYVS 1656
Query 1776 QQESSFVMMSAPPAEYKLQ-QGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMS 1834
+Q+S +++MS P + L G + A + G GHY + + D + S
Sbjct 1657 EQKSPWLLMSCTPTQVPLDTSGIWKTAIVFRGPVTAGHYMYAVNGTLISVYDANTRRRTS 1716
Query 1835 EYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPT 1894
+ K P TD+ Y TS+T+ K +Y LDGV T I+P Y K+ + Y+T PI++V
Sbjct 1717 DLKLPATDILYGPTSFTSDSKVETYYLDGVKRTTIDPDFSKYVKRGDYYFTTAPIEVV-A 1775
Query 1895 QPLPNASFDNFKLT-CSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYS 1953
P S+D F L+ C N + A+ N+ TK +L +T +P++ GDVVAI +
Sbjct 1776 APKLVTSYDGFYLSSCQNPQLAESFNKAINATKTGPMKL-LTMYPNVAGDVVAISDDNVV 1834
Query 1954 ASFKKGAKLLHKPIVWHINQATTKTTFKPNTWC-LRCLWSTKPVDTSNSFEVLAVEDTQG 2012
A G+ + KP+++ +PNTW L L ST V+T N+++VLAV+
Sbjct 1835 AH-PYGSLHMGKPVLFV---------TRPNTWKKLVPLLSTVVVNTPNTYDVLAVDPL-- 1882
Query 2013 MDNLACESQQPTSEEVVENPTIQKEVIEC-DVKTTEVVGNVILKPSDEG-VKVTQELGHE 2070
P + E E P K I +K T V+ P ++G + +E
Sbjct 1883 ----------PVNNETSEEPISVKAPIPLYGLKATMVLNGTTYVPGNKGHLLCLKEFTLT 1932
Query 2071 DLMAAYVENTS-ITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAIT 2129
DL YVE + K + LS LGL+ + +N + + AY
Sbjct 1933 DLQTFYVEGVQPFVLLKASHLSKVLGLRV--SDSSLHVNHLSKGVVYAYA---------- 1980
Query 2130 TSNCAKRLAQRVFNNYMPYVFTL-LFQLCTFTKSTNS------------RIRASLPTTIA 2176
A RL RV + + + T + + F +STN ++ +
Sbjct 1981 ----ATRLTTRVTTSLLGGLVTRSVRKTADFVRSTNPGSKCVGLLCLFYQLFMRFWLLVK 2036
Query 2177 KNSVKSVAKL-CLDAG-------INYVK-------SPKFSKLFTIAMWLLLLSICLGSLI 2221
K + V+ + + G +NY++ + KL +++ + CL
Sbjct 2037 KPPIVKVSGIIAYNTGCGVTTCVLNYLRSRCGNISWSRLLKLLRYMLYIWFVWTCLT--- 2093
Query 2222 CVTAAFGVLLSNFGAPSYCNGVRE--LYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYP 2279
GV LS APS + + + ++ + +C++G+DSLD YP
Sbjct 2094 ----ICGVWLSEPYAPSLVTRFKYFLGIVMPCDYVLVNETGTGWLHHLCMAGMDSLD-YP 2148
Query 2280 ALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS 2339
AL Q S + T + + E AY+L+T ++G+ A++ + Y + NS
Sbjct 2149 ALRMQQHRYGS-PYNYTYILMLLEAFFAYLLYTPALPIVGILAVLHLIVLYLPIP-LGNS 2206
Query 2340 WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVE 2399
WL+ F+ I+++ P ++M+RMYI A + +K ++H+ GC + C+MCYK+N A R+E
Sbjct 2207 WLVVFLYYIIRLVPFTSMLRMYIVIAFLWLCYKGFLHVRYGCNNVACLMCYKKNVAKRIE 2266
Query 2400 CTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPIN 2459
C+T+VNG+KR FYV ANGG FC HNWNC++CDT+ STFI +VA DLS QFKRPI
Sbjct 2267 CSTVVNGVKRMFYVNANGGTHFCTKHNWNCVSCDTYTVDSTFICRQVALDLSAQFKRPII 2326
Query 2460 PTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLP-INVI 2518
TD++ Y V SV V+NG ++ YF+ GQ++YER P+ F N+ L + KG+ P NV+
Sbjct 2327 HTDEAYYEVTSVEVRNGYVYCYFESDGQRSYERFPMDAFTNVSKLHYSELKGAAPAFNVL 2386
Query 2519 VFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSAT 2578
VFD ++ +E+A K+A++YY+QL C+PILL+D+ +V VGD ++ MF+AY +
Sbjct 2387 VFDATNRIEENAVKTAAIYYAQLACKPILLVDKRMVGVVGDDATIARAMFEAYAQNYLLK 2446
Query 2579 FSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVD--TDVDTKDVIECLKLSH 2636
+S+ M+K+K L +TA +++ G+ ++ VL FV + R D +DVDT D++ C++L H
Sbjct 2447 YSIAMDKVKHLYSTALQQISSGMTVESVLKVFVGSTRAEAKDLESDVDTNDLVSCIRLCH 2506
Query 2637 HSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYM 2696
E T DS NN + TY K + ++ ++G + NA+++NA +AK V+LIW D++
Sbjct 2507 QEGWEWTTDSWNNLVPTYIKQDTLSTLEVGQFMTANAKYVNANIAKGAAVNLIWRYADFI 2566
Query 2697 SLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGG--KIVSTCFKLMLKAT 2754
LSE +R+Q++ AA+K + +T ++ + V + T + GG +IVS L+
Sbjct 2567 KLSESMRRQLKVAARKTGLNLLVTTSSLKADVPCMVTPFKIIGGHRRIVSWRRVLIHVFM 2626
Query 2755 LLCVLA---ALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGF 2811
LL VL YI+ P+ ++ +K I + V RDI S D CFANK + F
Sbjct 2627 LLVVLNPQWFTPWYIMRPIEY---------NVVDFKVIDNAVIRDITSADQCFANKFSAF 2677
Query 2812 DAWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGN 2871
+ W+S R GSY N + CP+V +++ +G +VPGLP LR + L + AVG+
Sbjct 2678 ENWYSNRYGSYVNSRGCPMVVGVVSDIVGSLVPGLPARFLR-VGTTLLPLVNYGLGAVGS 2736
Query 2872 ICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRY 2931
+CYTP I Y F TSACVLAA CT+F A G+ +PYC D L++ + Y L+P Y
Sbjct 2737 VCYTPHYAINYDVFDTSACVLAATCTLFSSASGERMPYCADAALIQNASRYDMLKPHVMY 2796
Query 2932 VLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRA 2990
+ S I+FP V +V T EYC+ G C+ SE G+C+S RWV+NN ++R
Sbjct 2797 PFYEHSGYIRFPEVIS-AGVHIVRTMAMEYCKVGRCDVSEAGLCMSLQPRWVVNNAYFRQ 2855
Query 2991 LSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGE 3050
SGV+CG A +L N+ P+ PVGA+D++ S++ G ++A++V+ + YY ++FRR FG+
Sbjct 2856 QSGVYCGTSAFDLFMNMLLPIFTPVGAVDITTSILMGALLAVVVSMSLYYLLRFRRAFGD 2915
Query 3051 YNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFS 3110
Y+ V+ N L F+++ +LCL Y LP +Y++ +LY T YF +D++ + H+ + MF+
Sbjct 2916 YSGVIFTNILAFVLNVIVLCLEGPYPMLPSIYAMVFLYATCYFGSDIACMMHVSFLIMFA 2975
Query 3111 PIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKL 3170
+VP W+T +Y+ + +H WF + ++ V + F +F++AAL TF+L+KE++L+L
Sbjct 2976 GVVPLWVTVLYIVVVLSRHILWFASLCTKRTVQVGDLAFHSFQDAALQTFMLDKEVFLRL 3035
Query 3171 RSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPP 3230
+ E + Y +YLA+YNKYKY+SG +DT +YREAAC HL AL +SN G D +YQPP
Sbjct 3036 KRE--ISSDAYFKYLAMYNKYKYYSGPMDTAAYREAACSHLVMALEKYSNGGGDTIYQPP 3093
Query 3231 QTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDML 3290
+ S+ SA LQ+G +MA PSG VE C+V+V G+ TLNG+WLD+ V CPRHV+C+ +++
Sbjct 3094 RCSVASAALQAGLTRMAHPSGLVEPCLVKVNYGSMTLNGIWLDNFVICPRHVMCSRDELA 3153
Query 3291 NPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQ 3350
NP+Y L +R +N+ F V +RVIGH+M+ LL+L VD +NPKTP Y F+R+ GQ
Sbjct 3154 NPDYPRLSMRAANYDFHVSQNGHNIRVIGHTMEGSLLKLTVDVNNPKTPAYSFIRVSTGQ 3213
Query 3351 TFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTG 3410
S+LACY+G P+GVY C +R N T++ SFL GSCGS GF ++ V FCY+H +ELP G
Sbjct 3214 AMSLLACYDGLPTGVYTCTLRSNGTMRASFLCGSCGSPGFVMNGKEVQFCYLHQLELPNG 3273
Query 3411 VHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDF 3470
H GTD G FYGPF D+Q Q A D TIT+NVLAWLYAAV++G+ WFL + + + +F
Sbjct 3274 THTGTDFSGVFYGPFEDKQVPQLAAPDCTITVNVLAWLYAAVLSGENWFLTKSSISPAEF 3333
Query 3471 NLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDE 3530
N A+KY + +T + + +L PL+A+TGI+V M +ALK LL G GRTI+GS LEDE
Sbjct 3334 NNCAVKYMCQSVTSESLQVLQPLAAKTGISVERMLSALKVLLSAGFCGRTIMGSCSLEDE 3393
Query 3531 FTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLP 3590
TP+D+ RQ GV QGKF+ + + T W + F+ ++LIL+Q QW+ + LP
Sbjct 3394 HTPYDIGRQMLGVKLQGKFQSMFRWTLQWFAIIFVLTILILLQLAQWTFVGALPFTLLLP 3453
Query 3591 FTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMP---ASWVMRIMTWLELA 3647
+ LL+KHKH +L ++LLP AY+N Y P +++ + ++
Sbjct 3454 LIGFVAVCVGFVSLLIKHKHTYLTVYLLPVAMVTAYYNFQYTPEGVQGYLLSLYNYVNPG 3513
Query 3648 DTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQA 3707
+ G L ++ + A LL + R V DA R+W + + +Y + G+A A
Sbjct 3514 RIDVIGTDLLTMLIISVACTLL---SVRMVRTDAYSRIWYVCTAVGWLYNCWTGSADTVA 3570
Query 3708 ISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCC 3767
IS ++SV +NY+GV ++ A+ +V+V P + + +C+++ Y +GY C
Sbjct 3571 ISYLTFMVSVFTNYTGVACASLYAAQFMVWVLKFLDPTILLLYGRFRCVLVCYLLVGYLC 3630
Query 3768 CCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGK 3827
CYFG+F L+NR FR TLG Y+Y+VS+QE RYMNS GLLPP +S A LNIKL GIGG
Sbjct 3631 TCYFGVFNLINRLFRCTLGNYEYVVSSQELRYMNSHGLLPPTNSWQALMLNIKLAGIGGI 3690
Query 3828 PCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEK 3887
P +V+T+QS M+D+KCTSVVLLSVLQQLRVESSSKLWA CV+LHN+IL + TEAFE
Sbjct 3691 PIYRVSTIQSNMTDLKCTSVVLLSVLQQLRVESSSKLWALCVKLHNEILASNSPTEAFEA 3750
Query 3888 MVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVAN 3947
VSLLSVLLS+ GA++++ LC +L+N + LQA+ASEFS+L SY Y AQ+AY+ AVA
Sbjct 3751 FVSLLSVLLSLPGAINLDELCSSILENNSVLQAVASEFSNLSSYVDYENAQKAYDTAVAT 3810
Query 3948 GDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQ 4007
G + LKK++NVAKS D+D A RKLE+M++ AMT MYKQAR+ED+R+KVT+AMQ
Sbjct 3811 GAPASTVNALKKAMNVAKSVLDKDVATTRKLERMSELAMTAMYKQARAEDRRSKVTAAMQ 3870
Query 4008 TMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFT 4067
TMLF M+R+LD+DAL+NI+NNAR+G VPL +IP T A KL++VVPD+ Y T T T
Sbjct 3871 TMLFNMIRRLDSDALSNILNNARNGVVPLGVIPRTAANKLLLVVPDFSVYTATITMPTLT 3930
Query 4068 YASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALR--ANSAVKLQNNELSPVA 4125
YA + W++ QV DAD K V ++I +NS NLAWPL+VTA R A S VKLQNNEL P
Sbjct 3931 YAGSAWDVMQVADADGKTVNATDITRENSVNLAWPLVVTAQRQQATSPVKLQNNELMPQT 3990
Query 4126 LRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTE 4185
+++M+ AG +QTAC D A+AYYN +K GR V+A+L+D L +A+ KS G G + E
Sbjct 3991 VKRMNVVAGVSQTACVTD-AVAYYNATKEGRHVMAILADTDGLAFAKVEKSTGDGFVILE 4049
Query 4186 LEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLS 4245
LEPPC+F+ DTPKGP +KYLYF KGL NL RG VLG+LA TVRL AG+ATEV +NS++LS
Sbjct 4050 LEPPCKFMVDTPKGPALKYLYFTKGLKNLCRGTVLGTLACTVRLHAGSATEVASNSSILS 4109
Query 4246 FCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCL 4305
C+F+VDP YKDYL +GG PI NCVKML HTGTG AIT P+AN+DQESFGGASCCL
Sbjct 4110 LCSFSVDPEATYKDYLDNGGSPIGNCVKMLTPHTGTGLAITAKPDANIDQESFGGASCCL 4169
Query 4306 YCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLRE 4365
YCRCHI+HP G C KGK+VQIP NDP+GF +RN VC VC MW+GYGC C LRE
Sbjct 4170 YCRCHIEHPGASGVCKYKGKFVQIPLVGVNDPIGFCIRNVVCAVCNMWQGYGCPCSSLRE 4229
Query 4366 PLMQSADASTFLNR 4379
+Q+ D FLN
Sbjct 4230 INLQARD-ECFLNE 4242
>sp|P0C6U1|R1A_CVBQ Replicase polyprotein 1a OS=Bovine coronavirus
(strain Quebec) OX=11133 GN=1a PE=3 SV=1
Length=4383
Score = 3797 bits (9846), Expect = 0.0, Method: Composition-based stats.
Identities = 1308/4432 (30%), Positives = 2045/4432 (46%), Gaps = 390/4432 (9%)
Query 107 LVPHVGETPIAYRNVLLRKNGNKGA-------GGHSYGIDLKSYDLGDELGTDPIEDYEQ 159
+P IA + LRK G KGA GG + + K D D + +P + +
Sbjct 176 FMPVQSRKFIAPWVMYLRKCGEKGAYIKDYKRGGFEHVYNFKVEDAYDLVHDEPKGKFSK 235
Query 160 NWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYP---LDCIKDFLARAGKSMCTLS 216
L R G YVD C G L+ D + K++ +
Sbjct 236 KAYA---------LIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIW 286
Query 217 EQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSAK-----KFDTFKGEC 270
Q + +AW R + Q+ I+S D G
Sbjct 287 SQELPFD------------VTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSV 334
Query 271 ----PKFVFPLNSKVKVIQPRVEKKKTEGFMGR--IRSVYPVASPQECNNMHLSTLMKC- 323
P V+ +S + V+ + + Y V ++C + + C
Sbjct 335 VIKEPVHVYADDSIILRQHNLVDIMSCFYMEADAVVNAFYGVD-LKDCGFVMQFGYIDCE 393
Query 324 -NHCDEVSWQTCDFLKATCEH-CGTENLVIEGP-TTCGYLPTNAVVKMPCPACQDPEIGP 380
+ CD W + + CG + + G LP N V+
Sbjct 394 QDLCDFKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHT------------ 441
Query 381 EHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADI----GSGHT 436
S A Y ++ G FGGCV+ R W+P + + G +T
Sbjct 442 -KSAAGYGGFGCKDSFTLYGQTVVYFGGCVY----WSPARNIWIPILKSSVKSYDGLVYT 496
Query 437 GITGDNVETLNEDLL---EILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKS 493
G+ G +L+ L + + L + + + +++
Sbjct 497 GVVGCKAIVKETNLICKALYLDYVQHKCGNLHQRELLGVSDVWHKQLLLNRGVYKPLLEN 556
Query 494 LDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLD 553
+DY + + S + V + + R+ + G QA D
Sbjct 557 IDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSG---QAFC----------D 603
Query 554 AANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQWL 613
A + + +LD VD++ L + ++ +A Q
Sbjct 604 YAGKICHAVVSKSKELLD-------VSVDSLGAAIHYLNSKIVDLA-----------QHF 645
Query 614 SNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
S+ + V K+ F+ L AW + L G + +V+ I NI
Sbjct 646 SDFGTSFVSKIVHFFKTF-----TTSTALAFAWVLFHVL-HGAYIVVESDIYF-GKNIPR 698
Query 674 CVKCFIDVVNKALEMCIDQVT---IAGAKLRSLNLGEVFIAQSK------GLYRQCIRGK 724
++ +D + I G + + ++ SK GL
Sbjct 699 YASAVAQAFRSGAKVGLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERGLLHSSQLPL 758
Query 725 EQLQLLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGT 781
+ L MP K ++ +L+G D L V + L ++ V
Sbjct 759 DVYDLTMPSQVQKTKQKGIYLKGSGSDFSLADSVVEVVTTSLTPC-----GYSEPPKVAD 813
Query 782 PVCV-NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-K 838
+C+ + + + + DK + + + +R+ + VTF E TV E+ K
Sbjct 814 KICIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAG--RCVTFKEQPTVNEIASTPK 871
Query 839 NVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDL---LTNMG 895
+++ +ELD+ + +LN C + V+ ++ EF VV +A+ + L P +L +
Sbjct 872 TIKVFYELDKDFNTILNTACGEFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVS 931
Query 896 IDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDD--------------AECEEE 941
L + + +LFD+AGEE + ++YC+F P++++ +
Sbjct 932 AFLQKLEDNSLFLFDEAGEEVLAPKLYCAFTAPEDDDFLEESGVEEDDVEGEETDLTVTS 991
Query 942 EIDETCEHEYGTEDDYQGLPLEFG--ASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTP 999
+ E + L+ G +VEE+ + D +
Sbjct 992 AGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVQMSDFGDLESVIQDYENVCFEF 1051
Query 1000 EEPVNQFTGYLKLTDNVAIKCVDIVKEAQSA---------------------------NP 1032
+F L L A + ++ +
Sbjct 1052 YTTEPEFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFV 1111
Query 1033 MVIVN--AANIHLKHGGGVAGALNKATNGAMQKESD-DYIKLNGPLTVGGSCLLSGHNLA 1089
+VN ANI + GG VA D + + + L G +
Sbjct 1112 DTLVNKIPANIVVPQGGYVAD-----FAYWFLTLCDWQCVAYWKCIKCDLALKLKGLDAM 1166
Query 1090 KKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
VV GE + L+ + + L L + + V +
Sbjct 1167 FFYGDVVSHVCKCGESMVLID--VDVPFTAHFALKDKLFCAFITKRSVYKAACVVDVNDS 1224
Query 1150 QVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEE-----KSVVQKPVDV 1204
V+ K + + + + + T + +V D+
Sbjct 1225 HSMAVVDGKQIDDHRITSITSDKFDFIIGHGTSFSMTTFEIAQLYGSCITPNVCFVKGDI 1284
Query 1205 KPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVG 1264
K EV + + + + E ++ G
Sbjct 1285 IKVSKRVKAEVVVNPANGH-----MAHGGGVAKAIAVAAGQQFVKETTDMVKSKGVCATG 1339
Query 1265 DVITSGD------ITCVVIPSKKA--GGTTEMLSRALKKVPVDEYITT---------YPG 1307
D S + VV P + + +L R K + + + T P
Sbjct 1340 DCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISAGIFSVPS 1399
Query 1308 QGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPI 1367
Y L AK + + + + GT R I
Sbjct 1400 DVSLTYLLGTAKKQVVLVSNNQEDFDLISKCQITAVEGTKKLAERLSFNVGRS------I 1453
Query 1368 CMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIG 1427
+ A + F ++ + +++
Sbjct 1454 VYETDANKLILSNDVA----------------FVSTFNVLQDVLS--------------- 1482
Query 1428 YVTHGFNLEEAARCMRSLKAPAVVSVSSPDAVTTYNGYLTSSSKTSEEHFVETVSLAGSY 1487
+ H L++ AR V P+ N + + ++F
Sbjct 1483 -LRHDIALDDDARTFVQSNVDVV-----PEGWRVVNKFYQINGVRPVKYF---------- 1526
Query 1488 RDWSYSGQRTELGVEFLKRGDKIVYHTLESPVEFHLDGEVLSLDKLKSLLSLREVKTIKV 1547
G++ + Y S + ++ ++K+L + + +
Sbjct 1527 --------ECPGGIDICSQDKVFGYVQQGSFNK-------ATVAQIKALF----LDKVDI 1567
Query 1548 FTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSE 1607
TVD N + V + ++G+ G + DG +VTK K +N++GK FF + + +
Sbjct 1568 LLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLK 1627
Query 1608 AFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKF 1667
A D+ L Y + L + KW+ G + K A+NNC+++ L LQ L +KF
Sbjct 1628 AVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLNLKF 1687
Query 1668 NAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNV 1727
QEA+ R+G A F +L+LA G+ D R+ + + +L A +
Sbjct 1688 KIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEI 1747
Query 1728 VCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAP 1787
CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG+ + V+ + F++ S
Sbjct 1748 ACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLI-HCVRFDVPFLICSNT 1805
Query 1788 PAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFY-K 1846
PA KL +G AN + G+ + GHY H+ +++ D +++ K+++ G ++D Y K
Sbjct 1806 PASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCLYLK 1863
Query 1847 ETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLPNASFDNF 1905
T +Y LD V E +P L YY YYT++ I T + + NF
Sbjct 1864 NLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNF 1923
Query 1906 KLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDVVAIDYRHYSASFKKGAKLLH 1964
KL D LN GF + E VT +P GDVV Y +++G
Sbjct 1924 KLI--GHTVCDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGCITFG 1981
Query 1965 KPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFEVLAVEDTQGMDNLACESQQP 2023
KP++W ++ + + + +P+ N F+VL V+D +++ +
Sbjct 1982 KPVIWLSHEQASLNSLT---------YFNRPLLVDENKFDVLKVDDVDDGGDISESDAK- 2031
Query 2024 TSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSIT 2083
E E I+ ++ K +V +VI+ +K + L D+ ++
Sbjct 2032 ---EPKEINIIKLSGVK---KPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLTGCRCV 2085
Query 2084 IKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRV-- 2141
++ N LS A+ + TI + V L + N K + ++
Sbjct 2086 VRTANALSRAVNVPTIRKFIKFGMTLVSIPIDL-----LNLREIKPVFNVVKAVRNKISA 2140
Query 2142 FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFS 2201
N++ ++F LLF + + T +A K KL A N + K+S
Sbjct 2141 CFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---KLTCKLVALAFKNAFLTFKWS 2193
Query 2202 KLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSYCNGVRELYLNSSNVTT---- 2255
+ A + + + + I F L G P++ + + N+ ++ T
Sbjct 2194 VVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIVQWIKNTFSLVTICDL 2253
Query 2256 ---------MDFCEGSFPCSICLSGLDSLDSYPALETIQVTISS--YKLDLTILGLAAEW 2304
+C GS C CL+G D LD+Y A++ +Q + +L + E
Sbjct 2254 YSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIEL 2313
Query 2305 VLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYI 2362
+++Y L+T +FY L +Q+ + + ++ W + ++S+ M P +R YI
Sbjct 2314 IVSYALYTAWFYPLFALISIQILTTWLPELLMLSTLHWSVRLLVSLANMLPAHVFMRFYI 2373
Query 2363 FFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFC 2422
ASF ++ + H+ GC+ S C+ CYKRNR+ RV+C+TIV GM R + V ANGG GFC
Sbjct 2374 IIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRYYDVMANGGTGFC 2433
Query 2423 KTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYF 2482
H WNC++CD++ G+TFI+ E A DLS + KRPI PTD + + V V + L++
Sbjct 2434 SKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFY 2493
Query 2483 DKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLM 2542
D+ GQ+TY+ S FV+ NL + K ++V+V + + D++ +A+V+Y+Q +
Sbjct 2494 DRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVENDA--DKANFLNAAVFYAQSL 2551
Query 2543 CQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVA 2602
+PIL++D+ L++ T V+ MFD YVDTF + F V + L AL+ATAHS + +G
Sbjct 2552 FRPILMVDKILITTANTGTSVTETMFDVYVDTFLSMFDVDKKSLNALIATAHSSIKQGTQ 2611
Query 2603 LDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMT 2661
+ VL TF+S AR+ +D+DVDTK + + + + + LE+T +SCNN + TY K +N+
Sbjct 2612 ICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLELTDESCNNLVPTYLKGDNIV 2671
Query 2662 PRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTC 2721
DLG I +A+H+ VAK VS IW+V + LS + +++ A K + LT
Sbjct 2672 AADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSDFQHKLKKACCKTGLKLELTY 2731
Query 2722 ATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTN 2781
V+V+TT SLKGG + S + +L+C + + +MP +T+ D
Sbjct 2732 NKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLVCFI---GLWCLMPTYTVHKSDFQLP 2788
Query 2782 EIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREI 2839
YK + +GV RD+ D CFANK FD W+ G Y N +CP+V A++ ++
Sbjct 2789 VYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGLSYYSNSMACPIVVAVVDQDF 2848
Query 2840 GFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIF 2899
G V +P VLR LHF+ SA G CYTP I YS+F S CVL++ CT+F
Sbjct 2849 GSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQISYSNFYASGCVLSSACTMF 2907
Query 2900 KDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SIIQFPNTYLEGSVRVVTTFDA 2958
A G P PYCY L++ + YS L P RY L + I+ P EG VR+V T
Sbjct 2908 AMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGFIRLPEVLREGLVRIVRTRSM 2967
Query 2959 EYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGAL 3018
YCR G CE ++ GIC + +G WVLNN++YR+L G FCG D +LI +F L QPV L
Sbjct 2968 SYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGRDVFDLIYQLFKGLAQPVDFL 3027
Query 3019 DVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFL 3078
++AS +AG I+A++V YY +K +R FG+Y +V N +++ ++F +L + Y L
Sbjct 3028 ALTASSIAGAILAVIVVLGFYYLIKLKRAFGDYTSIVFVNVIVWCVNFMMLFVFQVYPTL 3087
Query 3079 PGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYL 3138
VY++ Y Y T YF +++S + HLQW M+ I+P W +Y+ + H W F+
Sbjct 3088 SCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFCLLYISVVVSNHAFWVFSYC- 3146
Query 3139 RKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGAL 3198
+++ + + TFEE AL TF++ K+ Y KL++ L +NRYL+LYNKY+Y+SG +
Sbjct 3147 -RQLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSDVAFNRYLSLYNKYRYYSGKM 3203
Query 3199 DTTSYREAACCHLAKALNDF-SNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3257
DT +YREAAC LAKA++ F +N+G+DVLYQPP S++++ LQSG KM P+ KVE C+
Sbjct 3204 DTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTSFLQSGIVKMVNPTSKVEPCI 3263
Query 3258 VQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRV 3317
V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +LL R ++ F V + L V
Sbjct 3264 VSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNLLCRVTSSDFTVLFDRLSLTV 3323
Query 3318 IGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIK 3377
+ + MQ C+L L V N +TPKY F ++PG+TF+VLA YNG P G + MR ++TIK
Sbjct 3324 MSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAAYNGKPQGAFHVTMRSSYTIK 3383
Query 3378 GSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTD 3437
GSFL GSCGSVG+ I DCV F YMH +EL TG H GTD G FYGP+ D Q Q D
Sbjct 3384 GSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDFNGDFYGPYKDAQVVQLPVQD 3443
Query 3438 TTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQT 3497
++N +AWLYAA++N WF+ ++ DFN+ A+ + + D V + L++ T
Sbjct 3444 YIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSNGFSQVKSDLV--IDALASMT 3501
Query 3498 GIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTH 3557
G+++ + AA+K L +NG GR I+GS EDE TP DV +Q +G+ Q K ++VKG
Sbjct 3502 GVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVYQQLAGIKLQSKRTRLVKGIV 3560
Query 3558 HWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFL 3617
W++ + I+ +W++F +V N L T + + + AMLLVKHKH +L +++
Sbjct 3561 CWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALCVISLAMLLVKHKHLYLTMYI 3619
Query 3618 LPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVL-LILMTAR 3675
+P L T+ Y N +V ++ + WL S+ Y D V+Y L++ ++ +T R
Sbjct 3620 IPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTYTDEVIYGMLLLIGMVFVTLR 3678
Query 3676 TVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAI 3735
++ D + + VI++V Y G+ L++ I + ++ S+ Y+ M A+ I
Sbjct 3679 SINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLASLFGTYTWTTALSMAAAKVI 3736
Query 3736 VFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQ 3795
V L F ++ +++ Y F+GY CY+GLF L+N FR+ LGVY+Y +S Q
Sbjct 3737 A-KWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFSLMNSLFRMPLGVYNYKISVQ 3795
Query 3796 EFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQ 3855
E RYMN+ GL PPK+S +A LN KLLGIGG P I+V+ QSK++DVKC + LL+ LQ
Sbjct 3796 ELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQFQSKLTDVKCANGGLLNCLQH 3855
Query 3856 LRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLCE 3909
L V S+SKLW C LHN+IL D AFEK+ LL VL + AVD I +C+
Sbjct 3856 LHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVLFANPAAVDSKCLTSIEEVCD 3915
Query 3910 EMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEF 3968
+ + LQA+ SEF ++ S+ Y A++ ++A ++G + + LK+L+K+ N+AKS +
Sbjct 3916 DYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGSANQQQLKQLEKACNIAKSAY 3975
Query 3969 DRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINN 4028
+RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++N
Sbjct 3976 ERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDN 4035
Query 4029 ARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQL 4088
A GCVPLN IP A L ++VPD Y D TYA +W+IQ + D+D QL
Sbjct 4036 AVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTYAGNVWQIQTIQDSDGTNKQL 4095
Query 4089 SEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNAL 4146
EI S + WPL++ A R N SA LQNNEL P L+ +G QT T
Sbjct 4096 HEI----SDDCNWPLVIIANRHNEVSATVLQNNELMPAKLKTQVVNSGPDQTCNTPTQ-- 4149
Query 4147 AYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLY 4206
YYNNS G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLY
Sbjct 4150 CYYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LELDPPCKFTVQDVKGLKIKYLY 4208
Query 4207 FIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQ 4266
F+KG N L RG V+G++++TVRLQAG ATE +NS++LS CAF+VDP K Y D++ GG
Sbjct 4209 FVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSLCAFSVDPKKTYLDFIQQGGT 4268
Query 4267 PITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKY 4326
PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+YCR ++HP+ G C L+GK+
Sbjct 4269 PIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIYCRARVEHPDVDGLCKLRGKF 4328
Query 4327 VQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
VQ+P DPV + L + VC VCG W+ CSC + +QS D + FLN
Sbjct 4329 VQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDTTVQSKD-TNFLN 4377
>sp|K9N638|R1A_MERS1 Replicase polyprotein 1a OS=Middle East respiratory
syndrome-related coronavirus (isolate United Kingdom/H123990006/2012)
OX=1263720 GN=1a PE=1 SV=1
Length=4391
Score = 3792 bits (9834), Expect = 0.0, Method: Composition-based stats.
Identities = 1259/3465 (36%), Positives = 1914/3465 (55%), Gaps = 221/3465 (6%)
Query 1090 KKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
++C V +L GE + + + E + + +A + A PL + ++V+
Sbjct 968 EECSEVEASDLEEGESECISETSTEQVDVSHEISDDEWAAAVDEAFPLDEAEDVTESVQE 1027
Query 1150 Q---VYIAVNDKALYEQVVMDYLDN---LKPRVEAPKQ----------------EEPPNT 1187
+ V + V D A + V+ D L + VE P Q E P
Sbjct 1028 EAQPVEVPVEDIA--QVVIADTLQETPVVSDTVEVPPQVVKLPSEPQTIQPEVKEVAPVY 1085
Query 1188 EDSKTEEKSVVQKPVDVKPK-------------IKACIDEVT-TTLEETKFLTNKLL--- 1230
E + +SV KP ++ K I C+ V ++ K +L
Sbjct 1086 EADTEQTQSVTVKPKRLRKKRNVDPLSNFEHKVITECVTIVLGDAIQVAKCYGESVLVNA 1145
Query 1231 ------LFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVIT------SGDITCVVIP 1278
I G + S+ ++ E ++ P VGD + + +I VV P
Sbjct 1146 ANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGHSLAKNILHVVGP 1205
Query 1279 SKKAGGTTEMLSRALKKVPVDEYI-TTYPGQGCAG--------YTLEEAKTALKKCKSAF 1329
+A +LS+ K + + T G G Y + EAKT + ++
Sbjct 1206 DARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIREAKTRVLVVVNSQ 1265
Query 1330 YVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQE 1389
V S + L LR + A++ + +C D A ++ K +
Sbjct 1266 DVYKSLTIVDIPQSLTFSYDGLRGAIRKAKDYGFTVFVCTDNSANTKVLRNKGVDYTKKF 1325
Query 1390 GIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAPA 1449
VD GV+++ YTSK+ + I+ + N + +++MP+GYV+HG +L +A +R + P
Sbjct 1326 LTVD-GVQYYCYTSKDTLDDILQQANK-SVGIISMPLGYVSHGLDLIQAGSVVRRVNVPY 1383
Query 1450 VVSVSSPDAVTTYNGYLTSSSKT-SEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGD 1508
V +++ + ++ K E F++ V G Y W EL V+ L+
Sbjct 1384 VCLLANKEQEAIL---MSEDVKLNPSEDFIKHVRTNGGYNSWHLV--EGELLVQDLRLNK 1438
Query 1509 KI------------VYHTLESPVEFHLDGEVLSLDKLKSLLSLREVK--TIKVFTTVDNT 1554
+ V++ +++ F + +L ++ L R + TI+V TVD
Sbjct 1439 LLHWSDQTICYKDSVFYVVKNSTAFPFE----TLSACRAYLDSRTTQQLTIEVLVTVDGV 1494
Query 1555 NLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAF-EYYH 1613
N T +++ TY Q G + +GAD++ P G + ++ + ++A E Y
Sbjct 1495 NFRTVVLNNKNTYRSQLGCVFFNGADISDTIPDEKQNGHSLYLADNLTADETKALKELYG 1554
Query 1614 TLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLE-VKFNAPAL 1672
+D +FL R+ S KWK + S+K +DNNCYL++V++ L L+ +KF PAL
Sbjct 1555 PVDPTFLHRFYSLKAAVHKWKMVVCDKVRSLKLSDNNCYLNAVIMTLDLLKDIKFVIPAL 1614
Query 1673 QEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE-SAKRVLNVVCKH 1731
Q A+ + + GD+ +F ALI+AY N T G D + +L A L SA+ V C
Sbjct 1615 QHAFMKHKGGDSTDFIALIMAYGNCTFGAPDDASRLLHTVLAKAELCCSARMVWREWCNV 1674
Query 1732 CGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEY 1791
CG K L G++A Y+G + ++L+ ++ C CG + + +V+ + ++++S P E
Sbjct 1675 CGIKDVVLQGLKACCYVGVQTVEDLRARMTYVCQCGGERHRQIVEHTTPWLLLSGTPNEK 1734
Query 1792 KLQQGT---FLCANEYTG-NYQCGHYTHITAKETL-YRIDGAHLTKMSEYKGPVTDVFYK 1846
+ T F+ N + G GHY H K L + D ++K S++K VTDV +
Sbjct 1735 LVTTSTAPDFVAFNVFQGIETAVGHYVHARLKGGLILKFDSGTVSKTSDWKCKVTDVLFP 1794
Query 1847 ETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYT-EQPIDLVPTQPLPNASFDNF 1905
Y++ V Y LDG TE++P L +Y KD Y+T E P+ P L + + N
Sbjct 1795 GQKYSSDCNVVRYSLDGNFRTEVDPDLSAFYVKDGKYFTSEPPVTYSPATILAGSVYTNS 1854
Query 1906 KLTCSNTKFADD-----LNQMTGF--TKPASRELSVTFFPDLNGDVVAIDYRHYSASFKK 1958
L S+ + D N + GF +KP +++ + +F P +GDV+ ++ Y +K
Sbjct 1855 CLVSSDGQPGGDAISLSFNNLLGFDSSKPVTKKYTYSFLPKEDGDVLLAEFDTYDPIYKN 1914
Query 1959 GAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDNLAC 2018
GA KPI+W + K N LR ++ P++ N F L+VE T
Sbjct 1915 GAMYKGKPILWVNKASYDTNLNKFNRASLRQIFDVAPIELENKFTPLSVEST-------- 1966
Query 2019 ESQQPTSEEVVENPTIQKE--VIECD-VKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
P V+ +Q+E +++C + V NV D G V + L EDL
Sbjct 1967 ----PVEPPTVDVVALQQEMTIVKCKGLNKPFVKDNVSFVADDSGTPVVEYLSKEDLHTL 2022
Query 2076 YVE-NTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAI------ 2128
YV+ + + K N LS L L T+ + IN V S L L +A+
Sbjct 2023 YVDPKYQVIVLKDNVLSSMLRLHTVESGD---INVVAASGSLTRKVKLLFRASFYFKEFA 2079
Query 2129 --------TTSNCAKRLAQRV---------FNNYMPYVFTLLFQLCTFTKSTNSRIRASL 2171
+C K + + + +++ +F L + +K + ++ S
Sbjct 2080 TRTFTATTAVGSCIKSVVRHLGVTKGILTGCFSFVKMLFMLPLAYFSDSKLGTTEVKVSA 2139
Query 2172 PTT---IAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG 2228
T + N VK +D ++ ++ + + + L + L S+ +
Sbjct 2140 LKTAGVVTGNVVKQCCTAAVDLSMDKLRRVDWKSTLRLLLMLCTTMVLLSSVYHLYVFNQ 2199
Query 2229 VLLSN-------------------FGAPSYCNGVRELY-LNSSNVTTMDFCEG-SFPCSI 2267
VL S+ G S C+G+ Y NS +V T FC S C+
Sbjct 2200 VLSSDVMFEDAQGLKKFYKEVRAYLGISSACDGLASAYRANSFDVPT--FCANRSAMCNW 2257
Query 2268 CLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVF 2327
CL DS+ YPAL+ +Q +S Y L++ L A E LAYML+T F L L+ + F
Sbjct 2258 CLISQDSITHYPALKMVQTHLSHYVLNIDWLWFAFETGLAYMLYTSAFNWLLLAGTLHYF 2317
Query 2328 FGY------FASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGC 2381
F + S+ + S W I P++ +VRMY A + + K Y H+++GC
Sbjct 2318 FAQTSIFVDWRSYNYAVSSAFWLFTHI----PMAGLVRMYNLLACLWLLRKFYQHVINGC 2373
Query 2382 TSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTF 2441
+ C++CYKRNR TRVE +T+V G KR+FY+ ANGG FC+ HNWNC++CDT G+TF
Sbjct 2374 KDTACLLCYKRNRLTRVEASTVVCGGKRTFYITANGGISFCRRHNWNCVDCDTAGVGNTF 2433
Query 2442 ISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNL 2501
I +EVA DL+ +RPIN TD+S Y VDSV VK + + + GQ YER PL F NL
Sbjct 2434 ICEEVANDLTTALRRPINATDRSHYYVDSVTVKETVVQFNYRRDGQPFYERFPLCAFTNL 2493
Query 2502 DNLR----ANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDV 2557
D L+ T G N I++D + ES ++SA VYYSQ++C+ ILL+D +LV+ V
Sbjct 2494 DKLKFKEVCKTTTGIPEYNFIIYDSSDRGQESLARSACVYYSQVLCKSILLVDSSLVTSV 2553
Query 2558 GDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQG 2617
GDS+E++ KMFD++V++F + ++V +KL+ L++TA + +G VL+TF+ AAR
Sbjct 2554 GDSSEIATKMFDSFVNSFVSLYNVTRDKLEKLISTARDGVRRGDNFHSVLTTFIDAARGP 2613
Query 2618 V-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHI 2676
V++DV+T ++++ ++ +H D+++T +S NN++ +Y K ++++ DLG+ IDCNA +
Sbjct 2614 AGVESDVETNEIVDSVQYAHKHDIQITNESYNNYVPSYVKPDSVSTSDLGSLIDCNAASV 2673
Query 2677 NAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKIS 2736
N V ++ N + IWN YM LS+ L++QIR A +K N+ FRLT + R N+++ + +
Sbjct 2674 NQIVLRNSNGACIWNAAAYMKLSDALKRQIRIACRKCNLAFRLTTSKLRANDNILSVRFT 2733
Query 2737 LKG---------GKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYK 2787
+ K + AT++ L A++ Y+ +P ++ + Y + I+ +K
Sbjct 2734 ANKIVGGAPTWFNALRDFTLKGYVLATIIVFLCAVLMYLCLPTFSMVPVEFYEDRILDFK 2793
Query 2788 AIQDGVTRDIISTDDCFANKHAGFDAWFSQR-GGSYKNDKSCPVVAAIITREIGFIVPGL 2846
+ +G+ RD+ D CFANKH F W+ + GG Y N +CP+ A+I G +P +
Sbjct 2794 VLDNGIIRDVNPDDKCFANKHRSFTQWYHEHVGGVYDNSITCPLTVAVIAGVAGARIPDV 2853
Query 2847 PGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKP 2906
P T L +N + F+ RVF+ G++CYTP I Y F+ S C+L +ECT+F+DA G+
Sbjct 2854 PTT-LAWVNNQIIFFVSRVFANTGSVCYTPIDEIPYKSFSDSGCILPSECTMFRDAEGRM 2912
Query 2907 VPYCYDTNLLEGSISYSELRPDTRYVLMDGSI-IQFPNTYLEGSVRVVTTFDAEYCRHGT 2965
PYC+D +L G+ +YS++RP RY L DG++ I+FP E ++R+ T +YCR G+
Sbjct 2913 TPYCHDPTVLPGAFAYSQMRPHVRYDLYDGNMFIKFPEVVFESTLRITRTLSTQYCRFGS 2972
Query 2966 CERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVV 3025
CE ++ G+C++T+G W + N+H+ GV+CG D ++++ + L QP+ ++ S+V
Sbjct 2973 CEYAQEGVCITTNGSWAIFNDHHLNRPGVYCGSDFIDIVRRLAVSLFQPITYFQLTTSLV 3032
Query 3026 AGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVF 3085
G + +T YY K +R F +Y + +++ +C V + Y+
Sbjct 3033 LGIGLCAFLTLLFYYINKVKRAFADYTQCAVIAVVAAVLNSLCICFVASIPLCIVPYTAL 3092
Query 3086 YLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRK--RVM 3143
Y Y TFYFTN+ +F+ H+ W+ MF PIVP W+T +Y + +H W + +K V
Sbjct 3093 YYYATFYFTNEPAFIMHVSWYIMFGPIVPIWMTCVYTVAMCFRHFFWVLAYFSKKHVEVF 3152
Query 3144 FNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSY 3203
+G +F++AA F++NK+ Y LR+ L Y+R+L L+NKYKYFSGA++T +Y
Sbjct 3153 TDGKLNCSFQDAASNIFVINKDTYAALRNS--LTNDAYSRFLGLFNKYKYFSGAMETAAY 3210
Query 3204 REAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCG 3263
REAA CHLAKAL +S +G+D+LYQPP SITS VLQSG KM+ PSG VE CMVQVTCG
Sbjct 3211 REAAACHLAKALQTYSETGSDLLYQPPNCSITSGVLQSGLVKMSHPSGDVEACMVQVTCG 3270
Query 3264 TTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQ---AGNVQLRVIGH 3320
+ TLNGLWLD+TV+CPRHV+C A+ + +PNY+ LLI +NHSF VQ LRV+GH
Sbjct 3271 SMTLNGLWLDNTVWCPRHVMCPADQLSDPNYDALLISMTNHSFSVQKHIGAPANLRVVGH 3330
Query 3321 SMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSF 3380
+MQ LL+L VD +NP TP Y F ++PG FSVLACYNG P+G + MRPN+TIKGSF
Sbjct 3331 AMQGTLLKLTVDVANPSTPAYTFTTVKPGAAFSVLACYNGRPTGTFTVVMRPNYTIKGSF 3390
Query 3381 LNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTI 3440
L GSCGSVG+ + ++FCYMH MEL G H G+ +G YG F+D+Q Q TD
Sbjct 3391 LCGSCGSVGYTKEGSVINFCYMHQMELANGTHTGSAFDGTMYGAFMDKQVHQVQLTDKYC 3450
Query 3441 TLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIA 3500
++NV+AWLYAA++NG WF+ T++ FN A+ + + L+ +TG+A
Sbjct 3451 SVNVVAWLYAAILNGCAWFVKPNRTSVVSFNEWALANQFTEFVG--TQSVDMLAVKTGVA 3508
Query 3501 VLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWM 3560
+ + A+++L G G+ ILGST+LEDEFTP DV Q GV Q +K+ GT HW+
Sbjct 3509 IEQLLYAIQQLY-TGFQGKQILGSTMLEDEFTPEDVNMQIMGVVMQSGVRKVTYGTAHWL 3567
Query 3561 LLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPS 3620
T +++ +I++Q+T+++L+ +++E + A MLLVKHKH FL LFLLP
Sbjct 3568 FATLVSTYVIILQATKFTLWNYLFETIPTQLFPLLFVTMAFVMLLVKHKHTFLTLFLLPV 3627
Query 3621 LATVAYFNMVYMP----ASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTART 3676
+ Y N+VY P +S ++ + WL + + D +Y S ++L+++ R
Sbjct 3628 AICLTYANIVYEPTTPISSALIAVANWLAPTNAYMRTTH-TDIGVYISMSLVLVIVVKRL 3686
Query 3677 VYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIV 3736
+ L + + +Y G A I+ V ++TS+Y+ V + LA+
Sbjct 3687 YNPSLSNFALALCSGVMWLYTYSIGEA-SSPIAYLVFVTTLTSDYTITVFVTVNLAKVCT 3745
Query 3737 FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQE 3796
+ Y P L + ++ I+L+Y LG+ C CYFG+F LLN R +GVYD+ VSTQE
Sbjct 3746 YAIFAYSPQLTLVFPEVKMILLLYTCLGFMCTCYFGVFSLLNLKLRAPMGVYDFKVSTQE 3805
Query 3797 FRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQL 3856
FR+M + L P++S +A LN KL+GIGG PCIKVA +QSK++D+KCTSVVLLSVLQQL
Sbjct 3806 FRFMTANNLTAPRNSWEAMALNFKLIGIGGTPCIKVAAMQSKLTDLKCTSVVLLSVLQQL 3865
Query 3857 RVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRA 3916
+E++S+ WA CV+ HNDIL A D +EAFEK VSL + L++ G VD++ L ++ D +
Sbjct 3866 HLEANSRAWAFCVKCHNDILAATDPSEAFEKFVSLFATLMTFSGNVDLDALASDIFDTPS 3925
Query 3917 TLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNVAKSEFDRDAAMQ 3975
LQA SEFS L ++A AQ+AY++A+ +GD S VLK L+K++N+AK+ +++D A+
Sbjct 3926 VLQATLSEFSHLATFAELEAAQKAYQEAMDSGDTSPQVLKALQKAVNIAKNAYEKDKAVA 3985
Query 3976 RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP 4035
RKLE+MADQAMT MYKQAR+EDK+AK+ SAMQTMLF M++KLDND LN II+NAR+GC+P
Sbjct 3986 RKLERMADQAMTSMYKQARAEDKKAKIVSAMQTMLFGMIKKLDNDVLNGIISNARNGCIP 4045
Query 4036 LNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDN 4095
L++IPL + KL VV+PD+ + + YA ALW+I + + D++IV+ S++ +D+
Sbjct 4046 LSVIPLCASNKLRVVIPDFTVWNQVVTYPSLNYAGALWDITVINNVDNEIVKSSDV-VDS 4104
Query 4096 SPNLAWPLIVTALRAN-SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKG 4154
+ NL WPL++ RA+ SAVKLQNNE+ P L+ M +AG QT C + ++LAYY +G
Sbjct 4105 NENLTWPLVLECTRASTSAVKLQNNEIKPSGLKTMVVSAGQEQTNC-NTSSLAYYEPVQG 4163
Query 4155 GRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNL 4214
+ ++ALLSD+ LKWAR DG ++ EL+PPC+F+ PKGP+++YLYF+K LNNL
Sbjct 4164 RKMLMALLSDNAYLKWARVEGKDGFVSV--ELQPPCKFLIAGPKGPEIRYLYFVKNLNNL 4221
Query 4215 NRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKM 4274
+RG VLG +AATVRLQAG+ TE +NS+VLS F VDP KAY D++ +GG P+TNCVKM
Sbjct 4222 HRGQVLGHIAATVRLQAGSNTEFASNSSVLSLVNFTVDPQKAYLDFVNAGGAPLTNCVKM 4281
Query 4275 LCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCA 4334
L TGTG AI+V PE+ DQE++GGAS CLYCR HI+HP+ G C KGK+VQIP C
Sbjct 4282 LTPKTGTGIAISVKPESTADQETYGGASVCLYCRAHIEHPDVSGVCKYKGKFVQIPAQCV 4341
Query 4335 NDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
DPVGF L NT C VC W GYGC+CD LR+ + + S FLN
Sbjct 4342 RDPVGFCLSNTPCNVCQYWIGYGCNCDSLRQAALPQSKDSNFLNE 4386
Score = 1023 bits (2645), Expect = 0.0, Method: Composition-based stats.
Identities = 326/1332 (24%), Positives = 553/1332 (42%), Gaps = 170/1332 (13%)
Query 13 HVQLSLPVLQVRDV---LVRGFGDSVEEALSEAREHLKNGTCGL-VEL-EKGVLPQLEQP 67
HV L++P+ ++ L F D E A + L L V + G L P
Sbjct 28 HVSLTVPLCGSGNLVEKLSPWFMDG-ENAYEVVKAMLLKKEPLLYVPIRLAGHTRHLPGP 86
Query 68 YVFIKRSDALSTNHGHKVVELVAEM---DGIQYGRS--GITLGVLVPHVGETPIAYRNVL 122
V++ N +V +A +G G + G +G+ P+ E +N+L
Sbjct 87 RVYLVERLIACEN--PFMVNQLAYSSSANGSLVGTTLQGKPIGMFFPYDIELVTGKQNIL 144
Query 123 LRKNGNKGAGGHSYGIDLKSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAV 182
LRK G GG+ Y Y+ + + ++D+E + K+ L ++L GG V
Sbjct 145 LRKYGR---GGYHY--TPFHYERDNTSCPEWMDDFEADPKGKYAQN----LLKKLIGGDV 195
Query 183 TRYVDNNFCGPDGYPLDCIKDFLARAG-KSMCTLSEQLDYIESKRGVYCCRDHEHEIAWF 241
T VD CG DG P+ +A+ G + + + G +++ + + W
Sbjct 196 TP-VDQYMCGVDGKPISAYAFLMAKDGITKLADVEADVAARADDEGFITLKNNLYRLVWH 254
Query 242 TERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRIR 301
ER D Y Q+ F I S + D + P + F L K+ + PR + + +
Sbjct 255 VERKDVPYPKQSIFTINSVVQKDGVENTPPHY-FTLGCKILTLTPRNKWSGVSDLSLKQK 313
Query 302 SVYPVASPQE---CNNMHLSTLMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGP-TTC 357
+Y + ++ S ++C C SW T + ++ CG + +
Sbjct 314 LLYTFYGKESLENPTYIYHSAFIECGSCGNDSWLTGNAIQGFACGCGASYTANDVEVQSS 373
Query 358 GYLPTNAVVKMPCPACQDPEIGP--EHSVADYHNHSNIETRLRKGGR--TRCFGGCVFAY 413
G + NA++ CP + +HSVA ++ + + + T FGG +AY
Sbjct 374 GMIKPNALLCATCPFAKGDSCSSNCKHSVAQLVSYLSERCNVIADSKSFTLIFGGVAYAY 433
Query 414 VGCYNKRAYWVPRASAD-------IGSGHTGITGDNVETLNEDLLEILSRERVNINIVGD 466
GC Y+VPRA + I +G TG + N L + + ++N VG+
Sbjct 434 FGCEEGTMYFVPRAKSVVSRIGDSIFTGCTGSWNKVTQIANM----FLEQTQHSLNFVGE 489
Query 467 FHLNEEVAIILASFSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIG-- 524
F +N+ V IL+ + + +K + + + + VT G + A N+G
Sbjct 490 FVVNDVVLAILSGTTTNVDKIRQLLKGVTLDKLRDYLADY-DVAVTAGPFMDNAINVGGT 548
Query 525 --QQRSVLTP---LCGFPSQAAGV------IRSIFARTLDAANHSIPDLQRAAVTILD-G 572
Q ++ P L G V + + TL HS+ L R +D G
Sbjct 549 GLQYAAITAPYVVLTGLGESFKKVATIPYKVCNSVKDTLTYYAHSV--LYRVFPYDMDSG 606
Query 573 ISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIE 632
+S S L D + SV ++ L +T ++S ++ + + + +
Sbjct 607 VSSFSELLFDCVDL-------SVASTYFLVRLLQDKTGDFMSTIITSCQTAVSKLLDTCF 659
Query 633 AKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQ 692
A FL D + + + + V + + VK +D++NK +++ +
Sbjct 660 EATEATFNFLLDLAGLFRIFLRNAYVYTSQGFVVVNGKVSTLVKQVLDLLNKGMQLLHTK 719
Query 693 VTIAGAKLRSLNLG--EVFIAQSKGLYRQCIRGK---EQLQLLMPLK-APKEVTFLEGDS 746
V+ AG+ + ++ E I S Y + K + L +++P + + K++ L+
Sbjct 720 VSWAGSNISAVIYSGRESLIFPSGTYYCVTTKAKSVQQDLDVILPGEFSKKQLGLLQPTD 779
Query 747 HDTVLTSEE----VVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDKE---QY 799
+ T ++ V G+LE + + IVG V ++ + + K+++ Y
Sbjct 780 NSTTVSVTVSSNMVETVVGQLEQ----TNMHSPDVIVGDYVIISEKLFVRSKEEDGFAFY 835
Query 800 CALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEVQGYKNVRITFELDERVDKVL-NEKC 858
A + G A +FRLKGGAP+K V FG D V EV ++V + + + +D +L +
Sbjct 836 PACTNGH-AVPTLFRLKGGAPVKKVAFGGDQVHEVAAVRSVTVEYNIHAVLDTLLASSSL 894
Query 859 SVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFS 918
+ V+ + EFA VV E V L + + DLD++ A Y F+ G+ ++S
Sbjct 895 RTFVVDKSLSIEEFADVVKEQVSDLLVKLLRGMPIPDFDLDDFIDAPCYCFNAEGDASWS 954
Query 919 SRMYCSFYPPD-----------EEEEDDAECEEEEIDETCEHEYGTEDDY------QGLP 961
S M S +P + + EE ++EC E E + + DD + P
Sbjct 955 STMIFSLHPVECDEECSEVEASDLEEGESECISETSTEQVDVSHEISDDEWAAAVDEAFP 1014
Query 962 LEFGASAETVRVEEEEEE--------------DWLDDTT---EQSEIEPEPEPTPEEP-- 1002
L+ A T V+EE + D L +T + E+ P+ P EP
Sbjct 1015 LD-EAEDVTESVQEEAQPVEVPVEDIAQVVIADTLQETPVVSDTVEVPPQVVKLPSEPQT 1073
Query 1003 ----------------------------------VNQFTGYLK--LTDNVAIKCVDIVKE 1026
V+ + + +T+ V I D ++
Sbjct 1074 IQPEVKEVAPVYEADTEQTQSVTVKPKRLRKKRNVDPLSNFEHKVITECVTIVLGDAIQV 1133
Query 1027 AQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGH 1086
A+ V+VNAAN HLKHGGG+AGA+N A+ GA+QKESD+YI GPL VG S LL GH
Sbjct 1134 AKCYGESVLVNAANTHLKHGGGIAGAINAASKGAVQKESDEYILAKGPLQVGDSVLLQGH 1193
Query 1087 NLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQT 1146
+LAK LHVVGP+ A +D+ LL Y+ N+ +++ PL+SAGIFG KP S ++
Sbjct 1194 SLAKNILHVVGPDARAKQDVSLLSKCYKAMNAYPLVVTPLVSAGIFGVKPAVSFDYLIRE 1253
Query 1147 VRTQVYIAVNDKALYEQVVMD--------YLDNLKPRVEAPKQE--EPPNTEDSKTEEKS 1196
+T+V + VN + +Y+ + + D L+ + K D+ K
Sbjct 1254 AKTRVLVVVNSQDVYKSLTIVDIPQSLTFSYDGLRGAIRKAKDYGFTVFVCTDNSANTKV 1313
Query 1197 VVQKPVDVKPKI 1208
+ K VD K
Sbjct 1314 LRNKGVDYTKKF 1325
>sp|P0C6U9|R1A_CVM2 Replicase polyprotein 1a OS=Murine coronavirus
(strain 2) OX=76344 GN=1a PE=3 SV=1
Length=4416
Score = 3615 bits (9375), Expect = 0.0, Method: Composition-based stats.
Identities = 1081/2927 (37%), Positives = 1593/2927 (54%), Gaps = 133/2927 (5%)
Query 1526 EVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIK 1585
+V S+ ++++LL + V TVD N + V +G+ G + DG +VTK++
Sbjct 1543 KVASVSQIRALL----ANKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR 1598
Query 1586 PHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIK 1645
H+GK FF A DE L +Y + L KW G + K
Sbjct 1599 CSAIHKGKVFFQYSGLSAADLVAVTDAFGFDEPQLLKYYNMLGMC-KWPVVVCGNYFAFK 1657
Query 1646 WADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDV 1705
++NNCY++ L LQ L +KF+ QEA+ R+G F +L+LA + E D
Sbjct 1658 QSNNNCYINVACLMLQHLSLKFHKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDS 1717
Query 1706 RETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCV 1765
+ M +L+ A+L A VCK CG K GV+AVM+ GTL +L G +I C
Sbjct 1718 TDFMRVVLREADLSGATCDFEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLAKGYTIACT 1776
Query 1766 CGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRI 1825
CG + Q F++ S P KL + AN +TG GHYTH+ K
Sbjct 1777 CGNKLV-HCTQLNVPFLICSNKPEGKKLPDDV-VAANIFTGG-SLGHYTHVKCKPKYQLY 1833
Query 1826 DGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYY 1884
D +++K+SE KG TD Y K T + K ++ LD V E P L YY + YY
Sbjct 1834 DACNVSKVSEAKGNFTDCLYLKNLKQTFSSKLTTFYLDDVKCVEYNPDLSQYYCESGKYY 1893
Query 1885 TEQPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNG 1942
T+ I T + NFKL A+ N GF E +T +P G
Sbjct 1894 TKPIIKAQFRTFEKVEGVYTNFKLV--GHSIAEKFNAKLGFDCNSPFTEYKITEWPTATG 1951
Query 1943 DVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF----KPNTWCLRCLWSTKPVDT 1998
DVV Y + + G KP++W ++ + + +P+ C ++ PVD
Sbjct 1952 DVVLASDDLYVSRYSGGCVTFGKPVIWLGHEEASLKSLTYFNRPSVVCEN-KFNVLPVDV 2010
Query 1999 SNSFE----VLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIECDV----------- 2043
S + AV T + A ++V + ++ +V+ +
Sbjct 2011 SEPTDKGPVPAAVLVTGALSGAATAPGTAKEQKVCASDSVVDQVVSGFLSDLSGATVDVK 2070
Query 2044 --------KTTEVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLALG 2095
K +V +V++ KV + L D+ ++ + NELS +
Sbjct 2071 EVKLNGVKKPIKVEDSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWMANELSRLVN 2130
Query 2096 LKTIATHGIAAINSVPWS--KILAYVKPFLGQAAITTSNCAKRLAQRVFNNY--MPYVFT 2151
T+ + V W KI+ K L + K + +V Y + + F
Sbjct 2131 SPTVREY-------VKWGMTKIVIPAKLVLLRDEKQEFVAPKVVKAKVIACYSAVKWFFL 2183
Query 2152 LLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLL 2211
F F + T +A K LC A N +++ ++ + +
Sbjct 2184 YCFSWIKFNTDN----KVIYTTEVAS---KLTFNLCCLAFKNALQTFNWNVVSRGFFLVA 2236
Query 2212 LLSICLGSLICVTAAF-------------------GVLLSNFGAPSYCNGVRELYLNSSN 2252
+ + + + + + FG + C+ LY S
Sbjct 2237 TVFLLWFNFLYANVILSDFYLPNIGFFPTFVGQIVAWVKTTFGIFTLCD----LYQVSDV 2292
Query 2253 VTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK--LDLTILGLAAEWVLAYML 2310
FC GS C +C SG D LD+Y A+ +Q + +++ L E V+ Y L
Sbjct 2293 GYRSSFCNGSMVCELCFSGFDMLDNYDAINVVQHVVDRRVSFDYISLFKLVVELVIGYSL 2352
Query 2311 FTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFASFY 2368
+T FY L MQ+ + F+ + W F + + M P ++R YI + Y
Sbjct 2353 YTVCFYPLFGLIGMQLLTTWLPEFFMLETMHWSARFFVFVANMLPAFTLLRFYIVVTAMY 2412
Query 2369 YIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWN 2428
I+ H+M GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WN
Sbjct 2413 KIFCLCRHVMYGCSRPGCLFCYKRNRSVRVKCSTVVGGTLRYYDVMANGGTGFCAKHQWN 2472
Query 2429 CLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQK 2488
CLNC F G+TFI+ E A DLS + KRP+NPTD + Y+V V ++ L++++ GQ+
Sbjct 2473 CLNCSAFGPGNTFITHEAAADLSKELKRPVNPTDSAYYLVTEVKQVGCSMRLFYERDGQR 2532
Query 2489 TYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILL 2548
Y+ S FV+++ L + KG +V+V + ++ D++ +A+V+Y+Q + +P+LL
Sbjct 2533 VYDDVSASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRPMLL 2590
Query 2549 LDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLS 2608
+++ L++ VS MFD YVD+ V + L + V AH+ L +GV L+ V+
Sbjct 2591 VEKKLITTANTGLSVSQTMFDLYVDSLLGVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMD 2650
Query 2609 TFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGA 2667
TF+ AR+ +D+DV+TK + + + + ++ ++ T +SCNN + TY K + + DLG
Sbjct 2651 TFIGCARRKCAIDSDVETKSITKSIMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGV 2710
Query 2668 CIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQV 2727
I NA+H+ A VAK+ NV+ IW+V + LS L+ ++R A K + +LT
Sbjct 2711 LIQNNAKHVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEAN 2770
Query 2728 VNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYK 2787
V ++TT SLKGG + S + + L+C + V + +MP + + D +K
Sbjct 2771 VPILTTPFSLKGGAVFSKVLQWLFVVNLICFI---VLWALMPTYAVHKSDMQLPLYASFK 2827
Query 2788 AIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREIGFIVPG 2845
I +GV RD+ TD CFANK FD W+ G Y+N ++CPVV A+I ++IG+ +
Sbjct 2828 VIDNGVLRDVTVTDACFANKFIQFDQWYESTFGLVYYRNSRACPVVVAVIDQDIGYTLFN 2887
Query 2846 LPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGK 2905
+P VLR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G
Sbjct 2888 VPTKVLR-YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGT 2946
Query 2906 PVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRHG 2964
P PYCY ++ + Y L P RY L + + I+FP EG VR+V T YCR G
Sbjct 2947 PHPYCYTEGIMHNASLYDSLAPHVRYNLANSNGYIRFPEVVSEGIVRIVRTRSMTYCRVG 3006
Query 2965 TCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASV 3024
CE +E G+C + + WVLNN +YRA+ G FCG +A +LI + LV+P+ ++AS
Sbjct 3007 LCEDAEEGVCFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASS 3066
Query 3025 VAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSV 3084
VAG I+AI+V A YY +K +R FG+Y VV N +++ ++F +L + Y L +Y+
Sbjct 3067 VAGAILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYAC 3126
Query 3085 FYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMF 3144
FY Y T YF +++S + HLQW M+ I+P W IYV + H W F+ +++
Sbjct 3127 FYFYTTLYFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFSYC--RKLGT 3184
Query 3145 NGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYR 3204
+ TFEE +L TF++ KE Y KL++ + +NRYL+LYNKY+YFSG +DT +YR
Sbjct 3185 EVRSDGTFEEMSLTTFMITKESYCKLKNS--VSDVAFNRYLSLYNKYRYFSGKMDTAAYR 3242
Query 3205 EAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCG 3263
EAAC LAKA+ F+ N+G DVLYQPP S+T++ LQSG KM FP+ KVE C+V VT G
Sbjct 3243 EAACSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVFPTSKVEPCVVSVTYG 3302
Query 3264 TTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQ 3323
TLNGLWLDD VYCPRHVIC++ DM +P+Y +LL R + F V +G + L V+ + MQ
Sbjct 3303 NMTLNGLWLDDKVYCPRHVICSSADMTDPDYSNLLCRVISSDFCVMSGRMSLTVMSYQMQ 3362
Query 3324 NCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNG 3383
LL L V NP TPKY F ++PG+TF+VLA YNG G + MR ++TIKGSFL G
Sbjct 3363 GSLLVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGKSQGAFHVTMRSSYTIKGSFLCG 3422
Query 3384 SCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLN 3443
SCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q Q D T T+N
Sbjct 3423 SCGSVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVN 3482
Query 3444 VLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLD 3503
V+AWLYAA++N WF+ + +L +FN+ AM + + D V L L++ TG+ V
Sbjct 3483 VVAWLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQ 3540
Query 3504 MCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLT 3563
+ AA+K L +G G+ ILGS +LEDE TP DV +Q +GV Q K ++VKGT W+L +
Sbjct 3541 ILAAIKRLY-SGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVVKGTCCWILAS 3599
Query 3564 FLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLAT 3623
L I+ +W++F +V + L TL + + AMLLVKHKH +L +F++P L T
Sbjct 3600 TLLFCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLVKHKHLYLTMFIMPVLCT 3658
Query 3624 VAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVL-LILMTARTVYDDA 3681
+ Y N +V S+ WL ++ Y D V+Y L++ ++ +T R++ D
Sbjct 3659 LFYTNYLVVYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLYGVVLLVAMVFVTMRSINHDV 3717
Query 3682 ARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVE 3741
++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA A V
Sbjct 3718 FSVMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWL 3773
Query 3742 YYPLLFITG-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYM 3800
+L+ T ++ ++L Y +GY CCCY+G+ LLN FR+ LGVY+Y +S QE RYM
Sbjct 3774 AVNVLYFTDVPQVKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYM 3833
Query 3801 NSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVES 3860
N+ GL PP++S +A LN KLLGIGG P I+V+ +QS+++DVKC +VVLL+ LQ L + S
Sbjct 3834 NANGLRPPRNSFEALVLNFKLLGIGGVPVIEVSQIQSRLTDVKCVNVVLLNCLQHLHIAS 3893
Query 3861 SSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLCEEMLDN 3914
SSKLW C LHN+IL D + AF+K+ LL VL + AVD I + ++ + +
Sbjct 3894 SSKLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRD 3953
Query 3915 RATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAA 3973
LQA+ SEF ++ S+ Y A++ ++A A+G + + +K+L+K+ N+AKS ++RD A
Sbjct 3954 STVLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRA 4013
Query 3974 MQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGC 4033
+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GC
Sbjct 4014 VARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMIRKLDNQALNSILDNAVKGC 4073
Query 4034 VPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINM 4093
VPLN IP T+ L ++VPD + D TYA +W IQ + DAD + QL+EI++
Sbjct 4074 VPLNAIPSLTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQSIQDADGAVKQLNEIDV 4133
Query 4094 DNSPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNN 4151
N+ WPL++ A R N S+V LQNNEL P LR +G+ T YYN
Sbjct 4134 ----NITWPLVIAANRHNEVSSVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ--CYYNT 4187
Query 4152 SKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGL 4211
+ G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG
Sbjct 4188 TGMGKIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGC 4246
Query 4212 NNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNC 4271
N L RG V+G+L++TVRLQAG ATE +NS + S CAF+VDP K Y DY+ GG P+TNC
Sbjct 4247 NTLARGWVVGTLSSTVRLQAGTATEYASNSAIRSLCAFSVDPKKTYLDYIQQGGAPVTNC 4306
Query 4272 VKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPT 4331
VKMLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4307 VKMLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPL 4366
Query 4332 TCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
DPV + L + VC VCG W+ CSC + + FLN
Sbjct 4367 G-IKDPVSYVLTHDVCQVCGFWRDGSCSCVGTGSQF--QSKDTNFLN 4410
Score = 348 bits (892), Expect = 1e-93, Method: Composition-based stats.
Identities = 205/998 (21%), Positives = 341/998 (34%), Gaps = 165/998 (17%)
Query 93 DGIQYGRSGITLGVLVPHVGETPIAYR-----NVLLRKNGNKGA---GGHSYGIDLKSYD 144
DG+ G +G +G VP A + ++LLRK GNKG+ G + + YD
Sbjct 158 DGVCLG-NGRFIGWFVPVTAIPAYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYD 216
Query 145 LGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPLDCIKDF 204
E D E+ N K+ A L + G ++D C G ++D+
Sbjct 217 FNVE---DACEEVHLNPKGKYSRKAYA-LLKGYRGVKSILFLDQYGCDYTGRLAKGLEDY 272
Query 205 LARAGKSMCTLSEQLDYIESKRGVYCCR-DHEHEIAWFTERSDKSYEH-QTPFEIKSAKK 262
CTL E + V+C D+E +AW +R ++ QT I+S
Sbjct 273 ------GDCTLEEMKELFP----VWCDSLDNEVVVAWHVDRDPRAVMRLQTLATIRSIGY 322
Query 263 FDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQE--CNNMHLSTL 320
+ ++ V V +P R V + + + L
Sbjct 323 VGQPTEDL------VDGDVVVREPAHLLAANAIVKRLPRLVETMLYTDSSVTEFCYKTKL 376
Query 321 MKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYLPTNAVVKMPCPACQDP---- 376
C + + C CG + G++P N + CP C
Sbjct 377 CDCGFITQFGYVDC---------CG------DACDFRGWVPGNMMDGFLCPGCSKSYMPW 421
Query 377 --EIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADIGSG 434
E + T + +G V VP SA S
Sbjct 422 ELEAQSSGVIPKGGVLFTQSTDTVNRESFKLYGHAV-------------VPFGSAVYWSP 468
Query 435 HTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSL 494
+ G+ L ++ D V A + ++
Sbjct 469 YPGMW--------------LPVIWSSVKSYADLTYTGVVGC---------KAIVQETDAI 505
Query 495 DYKSFKTIVES-CGNYKVTKGKPVKGA------WNIGQQRSVLTPLCGFPSQAAGVIRSI 547
+ V+ CGN + + N G +L + F + A
Sbjct 506 CRSLYMDYVQHKCGNLEQRAILGLDDVYHRQLLVNRGDYSLLLENVDLFVKRRAEFACKF 565
Query 548 FARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDA-------MVYTSDLLTNSVIIMAY 600
+ D +LDG+ +S L+ + MV S +T+ + MA
Sbjct 566 A---------TCGD--GLVPLLLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMAL 614
Query 601 VTGGLVQQTSQWLSNLLGTT--------VEKLRPIFEWIEAKLSAGVEFLKDAWEILKFL 652
+ V+ ++++ + G V +R I EW + + W + L
Sbjct 615 LFMHDVKVATKYVKKVTGKLAVRFKALGVAVVRKITEWFDLAVDTAAS--AAGWLCYQ-L 671
Query 653 ITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIA---GAKLRSLNLGEVF 709
+ G+F + G I SD + + VK F+D ++ ID ++++ G + V
Sbjct 672 VNGLFAVANGGITFLSD-VPELVKNFVDKFKVFFKVLIDSMSVSVLSGLTVVKTASNRVC 730
Query 710 IAQSKGLYRQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGEL--EALE 767
+A K + K +MP+ E T L G+ V+ + V + L +
Sbjct 731 LAGCKVY---EVVQKRLSAYVMPVGCN-EATCLVGEIEPAVVEDDVVDVVKAPLTYQGCC 786
Query 768 TPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSP---GLLATNNVFRLKGGAPIKGV 824
P SF +V + L + + D+ + G+L F G K V
Sbjct 787 KPPTSFEKICVV------DKLYMAKCGDQFYPVVVDNDTIGVLDQCWRFPCAG----KKV 836
Query 825 TFGED-TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKT 883
F + V E+ + ++I F LD D VL++ CS + V+ + E VV +AV T
Sbjct 837 EFNDKPKVKEIPSTRKIKINFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVEST 896
Query 884 LQPVSD---LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEE 940
L P + + T + L+ + YLFD+ GEE + +MYCSF PD+E+ C
Sbjct 897 LSPCKEHDVIGTKVCALLNRLAEDYVYLFDEGGEEVIAPKMYCSFSAPDDED-----CVA 951
Query 941 EEIDETCEHEYGTEDDYQGLPL----EFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPE 996
++ + E++ DD L E G + V V E + D E +IE +
Sbjct 952 ADVVDADENQGDDADDSAALVTDTQEEDGVAKGQVGVAESDAR---LDQVEAFDIEKVED 1008
Query 997 PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMV 1034
P E + T + I EA SA V
Sbjct 1009 PILNELSAELNAPADKTYEDVLAFDAIYSEALSAFYAV 1046
Score = 137 bits (346), Expect = 4e-30, Method: Composition-based stats.
Identities = 52/156 (33%), Positives = 78/156 (50%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV D++K + VIVN AN + HG GVAGA+ KA + KE+ D +K
Sbjct 1266 CITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKSFIKETADMVK 1325
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAG--EDIQLLKAAYENFNSQDILLAPLLS 1128
G VG +G NL K L++VGP+ + L+ AY++ N D ++ L+S
Sbjct 1326 NQGVCQVGECYESTGGNLCKTVLNIVGPDARGHGKQCYSFLERAYQHINKCDDVVTTLIS 1385
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + V V + N+K ++ +
Sbjct 1386 AGIFSVPTDVSLTYLIGVVTKNVILVSNNKDDFDVI 1421
Score = 43.1 bits (100), Expect = 0.16, Method: Composition-based stats.
Identities = 46/239 (19%), Positives = 82/239 (34%), Gaps = 28/239 (12%)
Query 1551 VDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDT-LRSEAF 1609
D V S Q + D+ K++ + +E P+D T AF
Sbjct 978 EDGVAKGQVGVAESDARLDQV-----EAFDIEKVEDPILNELSAELNAPADKTYEDVLAF 1032
Query 1610 EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNA 1669
+ + L + + +K G S NC+L S L+ +Q L ++F
Sbjct 1033 DAIY---SEALSAFYAVPGDETHFKVC---GFYSPAIERTNCWLRSTLIVMQSLPLEFKD 1086
Query 1670 PALQEAYYRARAGDAANFCALILAYSNKTVGEL--GDVRETMTHLLQHANLESAKRVLNV 1727
+Q+ + ++ F ++ K++ G V + L S K N
Sbjct 1087 LEMQKLWLSYKSSYNKEFVDKLVKSVPKSIILPQGGYVADFAYFFLSQ---CSFKAYANW 1143
Query 1728 VCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSA 1786
C C L G++A+ + G + VS C CG T L+ + + +
Sbjct 1144 RCLKCDM-DLKLQGLDAMFFYGDV--------VSHVCKCGTGMT--LLSADIPYTLHFG 1191
>sp|P0C6V0|R1A_CVMA5 Replicase polyprotein 1a OS=Murine coronavirus
(strain A59) OX=11142 GN=1a PE=1 SV=1
Length=4468
Score = 3608 bits (9355), Expect = 0.0, Method: Composition-based stats.
Identities = 1084/2919 (37%), Positives = 1600/2919 (55%), Gaps = 118/2919 (4%)
Query 1526 EVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIK 1585
+ S+ ++++LL + V TVD N + V +G+ G + DG +VTK++
Sbjct 1596 KEASVSQIRALL----ANKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR 1651
Query 1586 PHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIK 1645
++GK FF A + DE L +Y + L KW G + K
Sbjct 1652 CSAIYKGKVFFQYSDLSEADLVAVKDAFGFDEPQLLKYYTMLGMC-KWPVVVCGNYFAFK 1710
Query 1646 WADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDV 1705
++NNCY++ L LQ L +KF QEA+ R+G F +L+LA + E D
Sbjct 1711 QSNNNCYINVACLMLQHLSLKFPKWQWQEAWNEFRSGKPLRFVSLVLAKGSFKFNEPSDS 1770
Query 1706 RETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCV 1765
+ M +L+ A+L A L VCK CG K GV+AVM+ GTL +L G +I C
Sbjct 1771 IDFMRVVLREADLSGATCNLEFVCK-CGVKQEQRKGVDAVMHFGTLDKGDLVRGYNIACT 1829
Query 1766 CGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRI 1825
CG + Q F++ S P KL + AN +TG GHYTH+ K
Sbjct 1830 CGSKLV-HCTQFNVPFLICSNTPEGRKLPDDV-VAANIFTGG-SVGHYTHVKCKPKYQLY 1886
Query 1826 DGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYY 1884
D ++ K+SE KG TD Y K T + ++ LD V E +P L YY + YY
Sbjct 1887 DACNVNKVSEAKGNFTDCLYLKNLKQTFSSVLTTFYLDDVKCVEYKPDLSQYYCESGKYY 1946
Query 1885 TEQPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNG 1942
T+ I T + + NFKL A+ LN GF E +T +P G
Sbjct 1947 TKPIIKAQFRTFEKVDGVYTNFKLV--GHSIAEKLNAKLGFDCNSPFVEYKITEWPTATG 2004
Query 1943 DVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF----KPNTWCLRCLWSTKPVDT 1998
DVV Y + + G KP+VW ++ + + +P+ C ++ PVD
Sbjct 2005 DVVLASDDLYVSRYSSGCITFGKPVVWLGHEEASLKSLTYFNRPSVVCEN-KFNVLPVDV 2063
Query 1999 SNSFE------VLAVEDTQGMD----------NLACESQQ---PTSEEVVENPTI----Q 2035
S + + V G D AC S EV + P++
Sbjct 2064 SEPTDKGPVPAAVLVTGVPGADASAGAGIAKEQKACASASVEDQVVTEVRQEPSVSAADV 2123
Query 2036 KEVIECDVKTT-EVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNELSLAL 2094
KEV VK +V G+V++ KV + L D+ ++ + NELS +
Sbjct 2124 KEVKLNGVKKPVKVEGSVVVNDPTSETKVVKSLSIVDVYDMFLTGCKYVVWTANELSRLV 2183
Query 2095 GLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLF 2154
T+ + + KI+ K L + K + + Y + LL+
Sbjct 2184 NSPTVREYVKWGMG-----KIVTPAKLLLLRDEKQEFVAPKVVKAKAIACYCAVKWFLLY 2238
Query 2155 QLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLS 2214
+T++++ T +A K KLC A N +++ +S + + +
Sbjct 2239 CFSWIKFNTDNKVI--YTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLVATVF 2293
Query 2215 ICLGSLICVTAAFG-VLLSNFGA-PSYCNGVRELYLNSSNVTTM-------------DFC 2259
+ + + L N G P++ + + + V+T+ FC
Sbjct 2294 LLWFNFLYANVILSDFYLPNIGPLPTFVGQIVAWFKTTFGVSTICDFYQVTDLGYRSSFC 2353
Query 2260 EGSFPCSICLSGLDSLDSYPALETIQVTISSYK--LDLTILGLAAEWVLAYMLFTKFFYL 2317
GS C +C SG D LD+Y A+ +Q + +++ L E V+ Y L+T FY
Sbjct 2354 NGSMVCELCFSGFDMLDNYDAINVVQHVVDRRLSFDYISLFKLVVELVIGYSLYTVCFYP 2413
Query 2318 LGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYV 2375
L + MQ+ + F+ + W + + M P ++R YI + Y ++
Sbjct 2414 LFVLIGMQLLTTWLPEFFMLETMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVYCLCR 2473
Query 2376 HIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTF 2435
H+M GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNCLNC+++
Sbjct 2474 HVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLNCNSW 2533
Query 2436 CTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPL 2495
G+TFI+ E A DLS + KRP+NPTD + Y V V ++ L++++ GQ+ Y+
Sbjct 2534 KPGNTFITHEAAADLSKELKRPVNPTDSAYYSVTEVKQVGCSMRLFYERDGQRVYDDVNA 2593
Query 2496 SHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVS 2555
S FV+++ L + KG +V+V + ++ D++ A+V+Y+Q + +P+L++++ L++
Sbjct 2594 SLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLGAAVFYAQSLYRPMLMVEKKLIT 2651
Query 2556 DVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAAR 2615
VS MFD YVD+ V + L + V AH+ L +GV L+ V+ TF+ AR
Sbjct 2652 TANTGLSVSRTMFDLYVDSLLNVLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFIGCAR 2711
Query 2616 QGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACIDCNAR 2674
+ +D+DV+TK + + + + ++ ++ T +SCNN + TY K + + DLG I NA+
Sbjct 2712 RKCAIDSDVETKSITKSVMSAVNAGVDFTDESCNNLVPTYVKSDTIVAADLGVLIQNNAK 2771
Query 2675 HINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTK 2734
H+ A VAK+ NV+ IW+V + LS L+ ++R A K + +LT V ++TT
Sbjct 2772 HVQANVAKAANVACIWSVDAFNQLSADLQHRLRKACSKTGLKIKLTYNKQEANVPILTTP 2831
Query 2735 ISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVT 2794
SLKGG + S + + A L+C + V + +MP + + D +K I +GV
Sbjct 2832 FSLKGGAVFSRMLQWLFVANLICFI---VLWALMPTYAVHKSDMQLPLYASFKVIDNGVL 2888
Query 2795 RDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREIGFIVPGLPGTVLR 2852
RD+ TD CFANK FD W+ G Y+N K+CPVV A+I ++IG + +P TVLR
Sbjct 2889 RDVSVTDACFANKFNQFDQWYESTFGLAYYRNSKACPVVVAVIDQDIGHTLFNVPTTVLR 2948
Query 2853 AINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD 2912
LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P PYCY
Sbjct 2949 -YGFHVLHFITHAFATDSVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHPYCYT 3007
Query 2913 TNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEV 2971
++ + YS L P RY L + I+FP EG VRVV T YCR G CE +E
Sbjct 3008 GGVMHNASLYSSLAPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCEEAEE 3067
Query 2972 GICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIA 3031
GIC + + WVLNN +YRA+ G FCG +A +LI + LV+P+ ++AS VAG I+A
Sbjct 3068 GICFNFNRSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVRPIDFFALTASSVAGAILA 3127
Query 3032 ILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTF 3091
I+V A YY +K +R FG+Y VV N +++ ++F +L + Y L +Y+ FY Y T
Sbjct 3128 IIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYFYTTL 3187
Query 3092 YFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTFST 3151
YF +++S + HLQW M+ I+P W IYV + H W F+ +++ + T
Sbjct 3188 YFPSEISVVMHLQWLVMYGAIMPLWFCIIYVAVVVSNHALWLFSYC--RKIGTEVRSDGT 3245
Query 3152 FEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHL 3211
FEE AL TF++ KE Y KL++ + +NRYL+LYNKY+YFSG +DT +YREAAC L
Sbjct 3246 FEEMALTTFMITKESYCKLKNS--VSDVAFNRYLSLYNKYRYFSGKMDTAAYREAACSQL 3303
Query 3212 AKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGL 3270
AKA+ F+ N+G DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G TLNGL
Sbjct 3304 AKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCIVSVTYGNMTLNGL 3363
Query 3271 WLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLK 3330
WLDD VYCPRHVIC++ DM +P+Y +LL R ++ F V +G + L V+ + MQ C L L
Sbjct 3364 WLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSGRMSLTVMSYQMQGCQLVLT 3423
Query 3331 VDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGF 3390
V NP TPKY F ++PG+TF+VLA YNG P G + +R +HTIKGSFL GSCGSVG+
Sbjct 3424 VTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVTLRSSHTIKGSFLCGSCGSVGY 3483
Query 3391 NIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYA 3450
+ D V F YMH +EL TG H GTD G FYGP+ D Q Q D T T+NV+AWLYA
Sbjct 3484 VLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVAWLYA 3543
Query 3451 AVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
A+ N WF+ + +L +FN+ AM + + D V L L++ TG+ V + AA+K
Sbjct 3544 AIFNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLAAIKR 3601
Query 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLI 3570
L +G G+ ILGS +LEDE TP DV +Q +GV Q K +++KGT W+L + I
Sbjct 3602 L-HSGFQGKQILGSCVLEDE-TPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFLFCSI 3659
Query 3571 LVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMV 3630
+ +W++F +V + L TL + + AMLL+KHKH +L ++++P L T +V
Sbjct 3660 ISAFVKWTMFMYVTTH-MLGVTLCALCFVSFAMLLIKHKHLYLTMYIMPVLCTFYTNYLV 3718
Query 3631 YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVL-LILMTARTVYDDAARRVWTLM 3689
S+ WL ++ Y D V+Y L++ ++ +T R++ D ++ +
Sbjct 3719 VYKQSFRGLAYAWLSHFVPAVD-YTYMDEVLYGVVLLVAMVFVTMRSINHDVFSIMFLVG 3777
Query 3690 NVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFIT 3749
+++LV Y+G L++ + ++ + S+ Y+ TT++ LA A V +L+ T
Sbjct 3778 RLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWLAVNVLYFT 3833
Query 3750 G-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPP 3808
++ ++L Y +GY CCCY+G+ LLN FR+ LGVY+Y +S QE RYMN+ GL PP
Sbjct 3834 DVPQIKLVLLSYLCIGYVCCCYWGILSLLNSIFRMPLGVYNYKISVQELRYMNANGLRPP 3893
Query 3809 KSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQC 3868
++S +A LN KLLGIGG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+SKLW C
Sbjct 3894 RNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNSKLWQYC 3953
Query 3869 VQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLCEEMLDNRATLQAIA 3922
LHN+IL D + AF+K+ LL VL + AVD I + ++ + + LQA+
Sbjct 3954 STLHNEILATSDLSMAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNTVLQALQ 4013
Query 3923 SEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKM 3981
SEF ++ S+ Y A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+ RKLE+M
Sbjct 4014 SEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVARKLERM 4073
Query 3982 ADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPL 4041
AD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVPLN IP
Sbjct 4074 ADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVPLNAIPS 4133
Query 4042 TTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAW 4101
T+ L ++VPD + D TYA +W IQ + DAD + QL+EI++++ W
Sbjct 4134 LTSNTLTIIVPDKQVFDQVVDNVYVTYAGNVWHIQFIQDADGAVKQLNEIDVNS----TW 4189
Query 4102 PLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVL 4159
PL++ A R N S V LQNNEL P LR +G+ T YYN + G+ V
Sbjct 4190 PLVIAANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNTPTQ--CYYNTTGTGKIVY 4247
Query 4160 ALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMV 4219
A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N L RG V
Sbjct 4248 AILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNTLARGWV 4306
Query 4220 LGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHT 4279
+G+L++TVRLQAG ATE +NS +LS CAF+VDP K Y DY+ GG P+TNCVKMLC H
Sbjct 4307 VGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIKQGGVPVTNCVKMLCDHA 4366
Query 4280 GTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVG 4339
GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P DPV
Sbjct 4367 GTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG-IKDPVS 4425
Query 4340 FTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
+ L + VC VCG W+ CSC + + FLN
Sbjct 4426 YVLTHDVCQVCGFWRDGSCSCVGTGSQF--QSKDTNFLN 4462
Score = 351 bits (900), Expect = 1e-94, Method: Composition-based stats.
Identities = 190/995 (19%), Positives = 334/995 (34%), Gaps = 167/995 (17%)
Query 93 DGIQYGRSGITLGVLVPHVGETPIAYR-----NVLLRKNGNKGA---GGHSYGIDLKSYD 144
DG+ G +G +G VP A + ++LLRK GNKG+ G + + YD
Sbjct 158 DGVCLG-NGRFIGWFVPVTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYD 216
Query 145 LGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDG---YPLDCI 201
E D E+ N K+ A L + G +VD C G L+
Sbjct 217 FNVE---DACEEVHLNPKGKYSCKAYA-LLKGYRGVKPILFVDQYGCDYTGCLAKGLEDY 272
Query 202 KDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSA 260
D K + + D ++S E +AW +R ++ QT ++
Sbjct 273 GDLTLSEMKELFPVWR--DSLDS----------EVLVAWHVDRDPRAAMRLQTLATVRCI 320
Query 261 KKFDTFKGEC---------PKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQE 311
+ P + N+ VK + PR+ + Y E
Sbjct 321 DYVGQPTEDVVDGDVVVREPAHLLAANAIVKRL-PRLVETMLYTDSSVTEFCY-KTKLCE 378
Query 312 CNNMHLSTLMKC--NHCDEVSWQTCDFLKATCE-HCGTENLVIEGP-TTCGYLPTNAVVK 367
C + + C + CD W + + C + E + G +P V+
Sbjct 379 CGFITQFGYVDCCGDTCDFRGWVAGNMMDGFPCPGCTKNYMPWELEAQSSGVIPEGGVLF 438
Query 368 MPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRA 427
+ N E+ G FG V+ + C W+P
Sbjct 439 T-----------------QSTDTVNRESFKLYGHAVVPFGSAVY-WSPCPG---MWLPVI 477
Query 428 SADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSAF 487
+ + S ++G+T V A
Sbjct 478 WSSVKS-YSGLTYTGVVGC--------------------------------------KAI 498
Query 488 IDTIKSLDYKSFKTIVES-CGNYKVTKGKPVKGA------WNIGQQRSVLTPLCGFPSQA 540
+ ++ + V+ CGN + + N G +L + F +
Sbjct 499 VQETDAICRSLYMDYVQHKCGNLEQRAILGLDDVYHRQLLVNRGDYSLLLENVDLFVKRR 558
Query 541 AGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAY 600
A + +P L V + + MV S +T+ + MA
Sbjct 559 AEFACKFA----TCGDGLVPLLLDGLVPRSYYLIKSGQAFTSMMVNFSHEVTDMCMDMAL 614
Query 601 VTGGLVQQTSQWLSNLLGTT--------VEKLRPIFEWIEAKLSAGVEFLKDAWEILKFL 652
+ V+ ++++ + G V +R I EW + + W + L
Sbjct 615 LFMHDVKVATKYVKKVTGKLAVRFKALGVAVVRKITEWFDLAVDIAAS--AAGWLCYQ-L 671
Query 653 ITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTI---AGAKLRSLNLGEVF 709
+ G+F + G I + + + VK F+D ++ ID +++ +G + V
Sbjct 672 VNGLFAVANGVITFVQE-VPELVKNFVDKFKAFFKVLIDSMSVSILSGLTVVKTASNRVC 730
Query 710 IAQSKGLYRQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGEL--EALE 767
+A SK + K +MP+ E T L G+ V + V + L +
Sbjct 731 LAGSKVY---EVVQKSLSAYVMPVGC-SEATCLVGEIEPAVFEDDVVDVVKAPLTYQGCC 786
Query 768 TPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSP---GLLATNNVFRLKGGAPIKGV 824
P SF IV + L + + D+ + G+L F G K V
Sbjct 787 KPPTSFEKICIV------DKLYMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAG----KKV 836
Query 825 TFGED-TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKT 883
F + V ++ + ++ITF LD D VL++ CS + V+ + E VV +AV T
Sbjct 837 EFNDKPKVRKIPSTRKIKITFALDATFDSVLSKACSEFEVDKDVTLDELLDVVLDAVEST 896
Query 884 LQPVSD---LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEE 940
L P + + T + LD + YLFD+ G+E + RMYCSF PD+E+ C
Sbjct 897 LSPCKEHDVIGTKVCALLDRLAGDYVYLFDEGGDEVIAPRMYCSFSAPDDED-----CVA 951
Query 941 EEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWL------DDTTEQSEIEPE 994
++ + E++ +D L + + + E + + + + +
Sbjct 952 ADVVDADENQDDDAEDSAVLVADTQEEDGVAKGQVEADSEICVAHTGSQEELAEPDAVGS 1011
Query 995 PEPTP---EEPVNQFTGYLKLTDNVAIKCVDIVKE 1026
P E V + + + + A C D V
Sbjct 1012 QTPIASAEETEVGEASDREGIAEAKATVCADAVDA 1046
Score = 172 bits (437), Expect = 9e-41, Method: Composition-based stats.
Identities = 52/156 (33%), Positives = 79/156 (51%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV D++K + N VIVN AN + HG GVAGA+ + A KE+ D +K
Sbjct 1319 CITPNVCFVKGDVIKVVRLVNAEVIVNPANGRMAHGAGVAGAIAEKAGSAFIKETSDMVK 1378
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAG--EDIQLLKAAYENFNSQDILLAPLLS 1128
G VG +G L KK L++VGP+ + LL+ AY++ N D ++ L+S
Sbjct 1379 AQGVCQVGECYESAGGKLCKKVLNIVGPDARGHGKQCYSLLERAYQHINKCDNVVTTLIS 1438
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + V V + N++ ++ +
Sbjct 1439 AGIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFDVI 1474
Score = 43.5 bits (101), Expect = 0.11, Method: Composition-based stats.
Identities = 43/210 (20%), Positives = 79/210 (38%), Gaps = 21/210 (10%)
Query 1580 DVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVG 1639
++ K++ + E +T P+D T E + + L + + + +K
Sbjct 1055 EIEKVEDSILDELQTELNAPADKT--YEDVLAFDAVCSEALSAFYAVPSDETHFKVC--- 1109
Query 1640 GLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTV 1699
G S NC+L S L+ +Q L ++F +Q+ + +AG F ++ K++
Sbjct 1110 GFYSPAIERTNCWLRSTLIVMQSLPLEFKDLEMQKLWLSYKAGYDQCFVDKLVKSVPKSI 1169
Query 1700 GEL--GDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLK 1757
G V + L S K N C C L G++A+ + G +
Sbjct 1170 ILPQGGYVADFAYFFLSQ---CSFKAYANWRCLECDM-ELKLQGLDAMFFYGDV------ 1219
Query 1758 TGVSIPCVCGRDATQYLVQQESSFVMMSAP 1787
VS C CG T L+ + + +
Sbjct 1220 --VSHMCKCGNSMT--LLSADIPYTLHFGV 1245
>sp|P0C6V1|R1A_CVMJH Replicase polyprotein 1a OS=Murine coronavirus
(strain JHM) OX=11144 GN=1a PE=1 SV=1
Length=4474
Score = 3601 bits (9339), Expect = 0.0, Method: Composition-based stats.
Identities = 1073/2925 (37%), Positives = 1589/2925 (54%), Gaps = 123/2925 (4%)
Query 1526 EVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIK 1585
+ S+ ++++LL + V TVD N + V +G+ G + DG +VTK++
Sbjct 1595 KEASVSQIRALL----ANKVDVLCTVDGVNFRSCCVAEGEVFGKTLGSVFCDGINVTKVR 1650
Query 1586 PHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIK 1645
H+GK FF A + DE L +Y S L KW G + K
Sbjct 1651 CSAIHKGKVFFQYSGLSAADLAAVKDAFGFDEPQLLQYYSMLGMC-KWPVVVCGNYFAFK 1709
Query 1646 WADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDV 1705
++NNCY++ L LQ L +KF + R+G F +L+LA + E D
Sbjct 1710 QSNNNCYINVACLMLQHLSLKFPKWQWRRPGNEFRSGKPLRFVSLVLAKGSFKFNEPSDS 1769
Query 1706 RETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCV 1765
+ + L+ A+L A L +CK CG K GV+AVM+ GTL L G +I C
Sbjct 1770 TDFIRVELREADLSGATCDLEFICK-CGVKQEQRKGVDAVMHFGTLDKSGLVKGYNIACT 1828
Query 1766 CGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRI 1825
CG + Q F++ S P KL + AN +TG GHYTH+ K
Sbjct 1829 CGDKLV-HCTQFNVPFLICSNTPEGKKLPDDV-VAANIFTGG-SVGHYTHVKCKPKYQLY 1885
Query 1826 DGAHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYY 1884
D +++K+SE KG TD Y K T + +Y LD V +P L YY + YY
Sbjct 1886 DACNVSKVSEAKGNFTDCLYLKNLKQTFSSVLTTYYLDDVKCVAYKPDLSQYYCESGKYY 1945
Query 1885 TEQPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNG 1942
T+ I T + NFKL + A+ LN GF E +T +P G
Sbjct 1946 TKPIIKAQFRTFEKVEGVYTNFKLVGHD--IAEKLNAKLGFDCNSPFMEYKITEWPTATG 2003
Query 1943 DVVAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTF----KPNTWCLRCLWSTKPVDT 1998
DVV Y + + G KP++W ++ + + +P+ C ++ PVD
Sbjct 2004 DVVLASDDLYVSRYSGGCVTFGKPVIWRGHEEASLKSLTYFNRPSVVCEN-KFNVLPVDV 2062
Query 1999 SNSFE--------------------VLAVEDTQGMDNLACESQQPTSEEVVENP------ 2032
S + ++ E + AC S + V+E
Sbjct 2063 SEPTDRRPVPSAVLVTGAASGADASAISTEPGTAKEQKACASDSVEDQIVMEAQKKSSVT 2122
Query 2033 -TIQKEVIECDVKTT-EVVGNVILKPSDEGVKVTQELGHEDLMAAYVENTSITIKKPNEL 2090
KEV VK + +V++ KV + L D+ ++ + NEL
Sbjct 2123 TVAVKEVKLNGVKKPVKWNCSVVVNDPTSETKVVKSLSIVDVYDMFLTGCRYVVWTANEL 2182
Query 2091 SLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVF 2150
S + T+ + + SK++ L + K + + Y +
Sbjct 2183 SRLINSPTVREYVKWGM-----SKLIIPANLLLLRDEKQEFVAPKVVKAKAIACYGAVKW 2237
Query 2151 TLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWL 2210
LL+ +T++++ T +A K KLC A N +++ +S + +
Sbjct 2238 FLLYCFSWIKFNTDNKVI--YTTEVAS---KLTFKLCCLAFKNALQTFNWSVVSRGFFLV 2292
Query 2211 LLLSICLGSLICVTAAFG-VLLSNFGA-PSYCNGVRELYLNSSNVTTM------------ 2256
+ + + + L N G P + + + V T+
Sbjct 2293 ATVFLLWFNFLYANVILSDFYLPNIGPLPMFVGQIVAWVKTTFGVLTICDFYQVTDLGYR 2352
Query 2257 -DFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYK--LDLTILGLAAEWVLAYMLFTK 2313
FC GS C +C SG D LD+Y ++ +Q + +++ L E V+ Y L+T
Sbjct 2353 SSFCNGSMVCELCFSGFDMLDNYESINVVQHVVDRRVSFDYISLFKLVVELVIGYSLYTV 2412
Query 2314 FFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSAMVRMYIFFASFYYIW 2371
FY L + MQ+ + F+ + W + + M P ++R YI + Y ++
Sbjct 2413 CFYPLFVLVGMQLLTTWLPEFFMLGTMHWSARLFVFVANMLPAFTLLRFYIVVTAMYKVY 2472
Query 2372 KSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLN 2431
H+M GC+ C+ CYKRNR+ RV+C+T+V G R + V ANGG GFC H WNCLN
Sbjct 2473 CLCRHVMYGCSKPGCLFCYKRNRSVRVKCSTVVGGSLRYYDVMANGGTGFCTKHQWNCLN 2532
Query 2432 CDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYE 2491
C+++ G+TFI+ E A DLS + KRP+NPTD + Y V V ++ L++++ GQ+ Y+
Sbjct 2533 CNSWKPGNTFITHEAAADLSKELKRPVNPTDSAYYSVIEVKQVGCSMRLFYERDGQRVYD 2592
Query 2492 RHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQ 2551
S FV+++ L + KG +V+V + ++ D++ +A+V+Y+Q + +P+L++++
Sbjct 2593 DVSASLFVDMNGLLHSKVKGVPETHVVVVENEA--DKAGFLNAAVFYAQSLYRPMLMVEK 2650
Query 2552 ALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFV 2611
L++ VS MFD YV + V + L + V AH+ L +GV L+ V+ TFV
Sbjct 2651 KLITTANTGLSVSRTMFDLYVYSLLRHLDVDRKSLTSFVNAAHNSLKEGVQLEQVMDTFV 2710
Query 2612 SAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVENMTPRDLGACID 2670
AR+ +D+DV+TK + + + + ++ +EVT +SCNN + TY K + + DLG I
Sbjct 2711 GCARRKCAIDSDVETKSITKSVMAAVNAGVEVTDESCNNLVPTYVKSDTIVAADLGVLIQ 2770
Query 2671 CNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNV 2730
NA+H+ + VAK+ NV+ IW+V + LS L+ ++R A K + +LT V +
Sbjct 2771 NNAKHVQSNVAKAANVACIWSVDAFNQLSADLQHRLRKACVKTGLKIKLTYNKQEANVPI 2830
Query 2731 ITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQ 2790
+TT SLKGG + S + + A L+C + V + +MP + + D +K I
Sbjct 2831 LTTPFSLKGGAVFSRVLQWLFVANLICFI---VLWALMPTYAVHKSDMQLPLYASFKVID 2887
Query 2791 DGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAAIITREIGFIVPGLPG 2848
+GV RD+ TD CFANK FD W+ G Y+N K+CPVV A+I ++IG + +P
Sbjct 2888 NGVLRDVSVTDACFANKFNQFDQWYESTFGLVYYRNSKACPVVVAVIDQDIGHTLFNVPT 2947
Query 2849 TVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVP 2908
VLR LHF+ F+ CYTP I Y +F S CVL++ CT+ A G P P
Sbjct 2948 KVLR-YGFHVLHFITHAFATDRVQCYTPHMQIPYDNFYASGCVLSSLCTMLAHADGTPHP 3006
Query 2909 YCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRVVTTFDAEYCRHGTCE 2967
YCY ++ + YS L P RY L + I+FP EG VRVV T YCR G CE
Sbjct 3007 YCYTEGVMHNASLYSSLVPHVRYNLASSNGYIRFPEVVSEGIVRVVRTRSMTYCRVGLCE 3066
Query 2968 RSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAG 3027
+E GIC + + WVLNN +YRA+ G FCG +A +LI + LVQP+ ++AS VAG
Sbjct 3067 EAEEGICFNFNSSWVLNNPYYRAMPGTFCGRNAFDLIHQVLGGLVQPIDFFALTASSVAG 3126
Query 3028 GIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYL 3087
I+AI+V A YY +K +R FG+Y VV N +++ ++F +L + Y L +Y+ FY
Sbjct 3127 AILAIIVVLAFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVFQVYPTLSCLYACFYF 3186
Query 3088 YLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGV 3147
Y T YF +++S + HLQW M+ I+P W YV + H W F+ +++ +
Sbjct 3187 YTTLYFPSEISVVMHLQWLVMYGAIMPLWFCITYVAVVVSNHALWLFSYC--RKIGTDVR 3244
Query 3148 TFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAA 3207
+ TFEE AL TF++ KE Y KL++ + +NRYL+LYNKY+YFSG +DT +YREAA
Sbjct 3245 SDGTFEEMALTTFMITKESYCKLKNS--VSDVAFNRYLSLYNKYRYFSGKMDTATYREAA 3302
Query 3208 CCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTT 3266
C LAKA+ F+ N+G DVLYQPP S+T++ LQSG KM P+ KVE C+V VT G T
Sbjct 3303 CSQLAKAMETFNHNNGNDVLYQPPTASVTTSFLQSGIVKMVSPTSKVEPCVVSVTYGNMT 3362
Query 3267 LNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCL 3326
LNGLWLDD VYCPRHVIC++ DM +P+Y +LL R ++ F V + + L V+ + MQ L
Sbjct 3363 LNGLWLDDKVYCPRHVICSSADMTDPDYPNLLCRVTSSDFCVMSDRMSLTVMSYQMQGSL 3422
Query 3327 LRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCG 3386
L L V NP TPKY F ++PG+TF+VLA YNG P G + MR +HTIKGSFL GSCG
Sbjct 3423 LVLTVTLQNPNTPKYSFGVVKPGETFTVLAAYNGRPQGAFHVVMRSSHTIKGSFLCGSCG 3482
Query 3387 SVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLA 3446
SVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q Q D T T+NV+A
Sbjct 3483 SVGYVLTGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTVNVVA 3542
Query 3447 WLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCA 3506
WLYAA++N WF+ + +L +FN+ AM + + D V L L++ TG+ V + A
Sbjct 3543 WLYAAILNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLV--LDALASMTGVTVEQVLA 3600
Query 3507 ALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLT 3566
A+K L +G G+ ILGS +LEDE TP DV +Q +GV Q K +++KGT W+L +
Sbjct 3601 AIKRL-HSGFQGKQILGSCVLEDELTPSDVYQQLAGVKLQSKRTRVIKGTCCWILASTFL 3659
Query 3567 SLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAY 3626
I+ +W++F +V + L TL + AMLL+KHKH +L ++++P L T+ Y
Sbjct 3660 FCSIISAFVKWTMFMYVTTH-MLGVTLCALCFVIFAMLLIKHKHLYLTMYIMPVLCTLFY 3718
Query 3627 FNMVY--MPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVL-LILMTARTVYDDAAR 3683
N + S+ WL ++ Y D V+Y L++ ++ +T R++ D
Sbjct 3719 TNYLVVGYKQSFRGLAYAWLSYFVPAVD-YTYMDEVLYGVVLLVAMVFVTMRSINHDVFS 3777
Query 3684 RVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYY 3743
++ + +++LV Y+G L++ + ++ + S+ Y+ TT++ LA A V
Sbjct 3778 TMFLVGRLVSLVSMWYFGANLEEEVLLF--LTSLFGTYTW--TTMLSLATAKVIAKWLAV 3833
Query 3744 PLLFITG-NTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNS 3802
+L+ T ++ ++L Y +GY CCCY+G+ LLN FR+ LGVY+Y +S QE RYMN+
Sbjct 3834 NVLYFTDIPQIKLVLLSYLCIGYVCCCYWGVLSLLNSIFRMPLGVYNYKISVQELRYMNA 3893
Query 3803 QGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSS 3862
GL PP++S +A LN KLLGIGG P I+V+ +QS+++DVKC +VVLL+ LQ L + S+S
Sbjct 3894 NGLRPPRNSFEALMLNFKLLGIGGVPVIEVSQIQSRLTDVKCANVVLLNCLQHLHIASNS 3953
Query 3863 KLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------INRLCEEMLDNRA 3916
KLW C LHN+IL D + AF+K+ LL VL + AVD I + ++ + +
Sbjct 3954 KLWQYCSTLHNEILATSDLSVAFDKLAQLLVVLFANPAAVDSKCLASIEEVSDDYVRDNT 4013
Query 3917 TLQAIASEFSSLPSYAAYATAQEAYEQAVANGDS-EVVLKKLKKSLNVAKSEFDRDAAMQ 3975
LQA+ SEF ++ S+ Y A++ ++A A+G + + +K+L+K+ N+AKS ++RD A+
Sbjct 4014 VLQALQSEFVNMASFVEYELAKKNLDEAKASGSANQQQIKQLEKACNIAKSAYERDRAVA 4073
Query 3976 RKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVP 4035
RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN+I++NA GCVP
Sbjct 4074 RKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALNSILDNAVKGCVP 4133
Query 4036 LNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMDN 4095
LN IP T+ L ++VPD + D TYA +W IQ + DAD + QL+EI++++
Sbjct 4134 LNAIPPLTSNTLTIIVPDKQVFDQVVDNVYVTYAPNVWHIQSIQDADGAVKQLNEIDVNS 4193
Query 4096 SPNLAWPLIVTALRAN--SAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSK 4153
WPL+++A R N S V LQNNEL P LR +G+ YYN +
Sbjct 4194 ----TWPLVISANRHNEVSTVVLQNNELMPQKLRTQVVNSGSDMNCNIPTQ--CYYNTTG 4247
Query 4154 GGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNN 4213
G+ V A+LSD LK+ + K DG + EL+PPC+F KG K+KYLYF+KG N
Sbjct 4248 TGKIVYAILSDCDGLKYTKIVKEDGNCVV-LELDPPCKFSVQDVKGLKIKYLYFVKGCNT 4306
Query 4214 LNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVK 4273
L RG V+G+L++TVRLQAG ATE +NS +LS CAF+VDP K Y DY+ GG P+TNCVK
Sbjct 4307 LARGWVVGTLSSTVRLQAGTATEYASNSAILSLCAFSVDPKKTYLDYIQQGGVPVTNCVK 4366
Query 4274 MLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTC 4333
MLC H GTG AIT+ PEA +Q+S+GGAS C+YCR ++HP+ G C L+GK+VQ+P
Sbjct 4367 MLCDHAGTGMAITIKPEATTNQDSYGGASVCIYCRSRVEHPDVDGLCKLRGKFVQVPLG- 4425
Query 4334 ANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
DPV + L + VC VCG W+ CSC + + FLN
Sbjct 4426 IKDPVSYVLTHDVCQVCGFWRDGSCSCVGTGSQF--QSKDTNFLN 4468
Score = 356 bits (913), Expect = 3e-96, Method: Composition-based stats.
Identities = 203/998 (20%), Positives = 338/998 (34%), Gaps = 174/998 (17%)
Query 93 DGIQYGRSGITLGVLVPHVGETPIAYR-----NVLLRKNGNKGA---GGHSYGIDLKSYD 144
DG+ G +G +G VP A + ++LLRK GNKG+ G + + YD
Sbjct 158 DGVCLG-NGRFIGWFVPVTAIPEYAKQWLQPWSILLRKGGNKGSVTSGHFRRAVTMPVYD 216
Query 145 LGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDG---YPLDCI 201
E D E+ N K+ A L R G +VD C G L+
Sbjct 217 FNVE---DACEEVHLNPRGKYSCKAYA-LLRGYRGVKPILFVDQYGCDYTGCLAKGLEDY 272
Query 202 KDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSA 260
D TLSE + R D+E +AW +R ++ QT ++S
Sbjct 273 GDL---------TLSEMKELSPVWR---DSLDNEVVVAWHVDRDPRAVMRLQTLATVRSI 320
Query 261 KKF-----DTFKGEC----PKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQE 311
+ D G+ P + N+ VK + PR+ + Y +
Sbjct 321 EYVGQPIEDMVDGDVVMREPAHLLAPNAIVKRL-PRLVETMLYTDSSVTEFCY-KTKLCD 378
Query 312 CNNMHLSTLMKC--NHCDEVSWQTCDFLKATCE-HCGTENLVIEGP-TTCGYLPTNAVVK 367
C + + C + C W + + C + E + G +P V+
Sbjct 379 CGFITQFGYVDCCGDTCGFRGWVPGNMMDGFPCPGCCKSYMPWELEAQSSGVIPEGGVLF 438
Query 368 MPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRA 427
+ N E+ G FGG AY Y W+P
Sbjct 439 T-----------------QSTDTVNRESFKLYGHAVVPFGGA--AYWSPYPGM--WLPVI 477
Query 428 SADIGS----GHTGITG-DNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSA 482
+ + S +TG+ G + + + L ++ V N E IL
Sbjct 478 WSSVKSYSYLTYTGVVGCKAIVQETDAICRFLY-----MDYVQHKCGNLEQRAIL----- 527
Query 483 STSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPL-CGFPSQAA 541
LD + ++ + G+Y + N+ C F +
Sbjct 528 ----------GLDDVYHRQLLVNRGDYSLLL-------ENVDLFVKRRAEFACKFATCGD 570
Query 542 GVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDA-------MVYTSDLLTNS 594
G++ +LDG+ +S L+ + MV S + +
Sbjct 571 GLV----------------------PLLLDGLVPRSYYLIKSGQAFTSLMVNFSREVVDM 608
Query 595 VIIMAYVTGGLVQQTSQWLSNLLGTT--------VEKLRPIFEWIEAKLSAGVEFLKDAW 646
+ MA + V+ ++++ + G + +R I EW + + W
Sbjct 609 CMDMALLFMHDVKVATKYVKKVTGKVAVRFKALGIAVVRKITEWFDLAVDTAAS--AAGW 666
Query 647 EILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIA---GAKLRSL 703
+ L+ G+F + G I + + + VK F+D ++ ID ++++ G +
Sbjct 667 LCYQ-LVNGLFAVANGVITFIQE-VPELVKNFVDKFKTFFKVLIDSMSVSILSGLTVVKT 724
Query 704 NLGEVFIAQSKGLYRQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGEL 763
V +A SK + K +MP+ E T L G+ V + V + L
Sbjct 725 ASNRVCLAGSKVY---EVVQKSLPAYIMPVGC-SEATCLVGEIEPAVFEDDVVDVVKAPL 780
Query 764 --EALETPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSP---GLLATNNVFRLKGG 818
+ P SF IV + L + + D+ + G+L F G
Sbjct 781 TYQGCCKPPSSFEKICIV------DKLYMAKCGDQFYPVVVDNDTVGVLDQCWRFPCAG- 833
Query 819 APIKGVTFGED-TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVA 877
K V F + V EV + ++I F LD D VL++ CS + V+ + E VV
Sbjct 834 ---KKVVFNDKPKVKEVPSTRKIKIIFALDATFDSVLSKACSEFEVDKDVTLDELLDVVL 890
Query 878 EAVVKTLQPVSD---LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEED 934
+AV TL P + + T + L+ YLFD+ GEE +SRMYCSF PDE+
Sbjct 891 DAVESTLSPCKEHGVIGTKVCALLERLVDDYVYLFDEGGEEVIASRMYCSFSAPDEDCVA 950
Query 935 DAECEEEE------IDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQ 988
+E D E+D A +E +E +
Sbjct 951 TDVVYADENQDDDADDPVVLVADTQEEDGVAREQVDSADSEICVAHTGGQEMT---EPDV 1007
Query 989 SEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKE 1026
+ E V + + + A C D +
Sbjct 1008 VGSQTPIASAEETEVGEACDREGIAEVKATVCADALDA 1045
Score = 139 bits (350), Expect = 1e-30, Method: Composition-based stats.
Identities = 54/156 (35%), Positives = 79/156 (51%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV D++K + VIVN AN + HG GVAGA+ KA A E+ D +K
Sbjct 1318 CITPNVCFVKGDVIKVLRRVGAEVIVNPANGRMAHGAGVAGAIAKAAGKAFINETADMVK 1377
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAG--EDIQLLKAAYENFNSQDILLAPLLS 1128
G VGG +G L KK L++VGP+ E LL+ AY++ N D ++ L+S
Sbjct 1378 AQGVCQVGGCYESTGGKLCKKVLNIVGPDARGHGNECYSLLERAYQHINKCDNVVTTLIS 1437
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + V V + N++ ++ +
Sbjct 1438 AGIFSVPTDVSLTYLLGVVTKNVILVSNNQDDFDVI 1473
Score = 47.4 bits (111), Expect = 0.007, Method: Composition-based stats.
Identities = 50/205 (24%), Positives = 81/205 (40%), Gaps = 23/205 (11%)
Query 1580 DVTKIKPHVNHEGKTFFVLPSDDT-LRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQV 1638
D+ K++ + E +T P+D T AF+ ++ S S H K V
Sbjct 1054 DIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPSDETHFK------V 1107
Query 1639 GGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKT 1698
G S NC+L S L+ +Q L ++F +Q+ + +AG F ++ + K+
Sbjct 1108 CGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKLVKSAPKS 1167
Query 1699 VGEL--GDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNL 1756
+ G V + L S K N C CG L G++AV + G +
Sbjct 1168 IILPQGGYVADFAYFFLSQ---CSFKVHANWRCLKCGM-ELKLQGLDAVFFYGDV----- 1218
Query 1757 KTGVSIPCVCGRDATQYLVQQESSF 1781
VS C CG T L+ + +
Sbjct 1219 ---VSHMCKCGNSMT--LLSADIPY 1238
>sp|P0C6T8|R1A_CVBEN Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-ENT) OX=233262 GN=1a PE=3 SV=1
Length=4383
Score = 3563 bits (9239), Expect = 0.0, Method: Composition-based stats.
Identities = 1078/2892 (37%), Positives = 1614/2892 (56%), Gaps = 107/2892 (4%)
Query 1528 LSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPH 1587
++ ++K+L + + + TVD N + V + ++G+ G + DG +VTK K
Sbjct 1552 ATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCD 1607
Query 1588 VNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWA 1647
+N++GK FF + + +A D+ L Y + L + KW+ G + K A
Sbjct 1608 INYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQA 1667
Query 1648 DNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRE 1707
+NNC+++ L LQ L +KF QEA+ R+G A F +L+LA G+ D R+
Sbjct 1668 NNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRD 1727
Query 1708 TMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCG 1767
+ + +L A + CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG
Sbjct 1728 FLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCG 1786
Query 1768 RDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDG 1827
+ + V+ + F++ S PA KL +G AN + G+ + GHY H+ +++ D
Sbjct 1787 KKLI-HCVRFDVPFLICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDA 1843
Query 1828 AHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTE 1886
+++ K+++ G ++D Y K T +Y LD V E P L YY YYT+
Sbjct 1844 SNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYNPDLSQYYCDGGKYYTQ 1903
Query 1887 QPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDV 1944
+ I T + + NFKL D LN GF + E VT +P GDV
Sbjct 1904 RIIKAQFKTFEKVDGVYTNFKLI--GHTICDILNAKLGFDSSKEFVEYKVTEWPTATGDV 1961
Query 1945 VAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFE 2003
V Y +++G KP++W ++ + + + +P+ N F+
Sbjct 1962 VLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFD 2012
Query 2004 VLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKV 2063
VL V+D +++ + E E I+ ++ K +V +VI+ +K
Sbjct 2013 VLKVDDVDDGGDISESDAK----ESKEINIIKLSGVK---KPFKVEDSVIVNDDTSEIKY 2065
Query 2064 TQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFL 2123
+ L D+ ++ ++ N LS+A+ + TI + V L
Sbjct 2066 VKSLSIVDVYDMWLTGCRYVVRTANALSMAVNVPTIRKFIKFGMTLVSIPIDL-----LN 2120
Query 2124 GQAAITTSNCAKRLAQRV--FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVK 2181
+ N K + ++ N++ ++F LLF + + T +A K
Sbjct 2121 LREIKPVFNVVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---K 2173
Query 2182 SVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSY 2239
KL A N + K+S + A + + + + I F L G P++
Sbjct 2174 LTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTF 2233
Query 2240 CNGVRELYLNSSNVTT-------------MDFCEGSFPCSICLSGLDSLDSYPALETIQV 2286
+ + ++ ++ T +C GS C CL+G D LD+Y A++ +Q
Sbjct 2234 VGKIAQWIKSTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQY 2293
Query 2287 TISS--YKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLM 2342
+ +L + E +++Y L+T +FY L +Q+ + F+ ++ W +
Sbjct 2294 EADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSV 2353
Query 2343 WFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTT 2402
++S+ M P +R YI ASF ++ + H+ GC+ C+ CYKRNR+ RV+C+T
Sbjct 2354 RLLVSLANMLPAHVFMRFYIIIASFIKLFILFRHVAYGCSKPGCLFCYKRNRSLRVKCST 2413
Query 2403 IVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTD 2462
IV GM R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD
Sbjct 2414 IVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTD 2473
Query 2463 QSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDG 2522
+ + V V + L++++ GQ+TY+ S FV+ NL + KG ++V+V +
Sbjct 2474 VAYHTVTDVKQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVEN 2533
Query 2523 KSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVP 2582
+ D++ +A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V
Sbjct 2534 DA--DKANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVD 2591
Query 2583 MEKLKALVATAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLE 2641
+ L AL+ATAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE
Sbjct 2592 KKSLNALIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLE 2651
Query 2642 VTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQ 2701
+T +SCNN + TY K +N+ DLG I +A+H+ VAK VS IW+V + LS
Sbjct 2652 LTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSD 2711
Query 2702 LRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAA 2761
+ +++ A K + +LT V+V+TT SLKGG + S + +L+C +
Sbjct 2712 FQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFLLSLVCFI-- 2769
Query 2762 LVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG- 2820
+ +MP +T+ D YK + +GV RD+ D CFANK FD W+ G
Sbjct 2770 -GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGL 2828
Query 2821 -SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
Y N +CP+V A++ +++G V +P VLR LHF+ SA G CYTP
Sbjct 2829 SYYSNSMACPIVVAVVDQDLGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQ 2887
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SI 2938
I YS+F S CVL++ CT+F A G P PYCY L++ + YS L P RY L +
Sbjct 2888 ISYSNFYASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGF 2947
Query 2939 IQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGV 2998
I+FP EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG
Sbjct 2948 IRFPEVLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGR 3007
Query 2999 DAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAAN 3058
D +LI +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N
Sbjct 3008 DVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVN 3067
Query 3059 ALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWIT 3118
+++ ++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W
Sbjct 3068 VIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFC 3127
Query 3119 AIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPL 3178
+Y+ + H W F +R+ + + TFEE AL TF++ K+ Y KL++ L
Sbjct 3128 LLYISVVVSNHAFWVFAYC--RRLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSD 3183
Query 3179 TQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDF-SNSGADVLYQPPQTSITSA 3237
+NRYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F +N+G+DVLYQPP S++++
Sbjct 3184 VAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTS 3243
Query 3238 VLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDL 3297
LQSG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +L
Sbjct 3244 FLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNL 3303
Query 3298 LIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLAC 3357
L R ++ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA
Sbjct 3304 LCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAA 3363
Query 3358 YNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 3417
YNG P G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD
Sbjct 3364 YNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDF 3423
Query 3418 EGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 3477
G FYGP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+
Sbjct 3424 NGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSN 3483
Query 3478 NYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVV 3537
+ + D V + L++ TG+++ + AA+K L +NG GR I+GS EDE TP DV
Sbjct 3484 GFSQVKSDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVY 3540
Query 3538 RQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA 3597
+Q +G+ Q K ++VKG W++ + I+ +W++F +V N L T +
Sbjct 3541 QQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALC 3599
Query 3598 IAACAMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRL 3656
+ + AMLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y
Sbjct 3600 VISLAMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTY 3658
Query 3657 KDCVMYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVI 3715
D V+Y L++ ++ +T R++ D + + VI++V Y G+ L++ I + ++
Sbjct 3659 TDEVIYGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLA 3716
Query 3716 SVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
S+ Y+ M A+ I V L F ++ +++ Y F+GY CY+GLF
Sbjct 3717 SLFGTYTWTTALSMAAAKVIA-KWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFS 3775
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
L+N FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+
Sbjct 3776 LMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQF 3835
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL
Sbjct 3836 QSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVL 3895
Query 3896 LSMQGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
+ AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G
Sbjct 3896 FANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGS 3955
Query 3950 S-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQT 4008
+ + LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QT
Sbjct 3956 ANQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQT 4015
Query 4009 MLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTY 4068
MLF+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TY
Sbjct 4016 MLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 4075
Query 4069 ASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVAL 4126
A +W+IQ + D+D QL+EI S + WPL++ A R N SA LQNNEL P L
Sbjct 4076 AGNVWQIQTIQDSDGTNKQLNEI----SDDCNWPLVIIANRHNEVSATVLQNNELMPAKL 4131
Query 4127 RQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTEL 4186
+ +G QT T YYNNS G+ V A+LSD LK+ + K DG + EL
Sbjct 4132 KTQVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LEL 4188
Query 4187 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4246
+PPC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS
Sbjct 4189 DPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSL 4248
Query 4247 CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4306
CAF+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+Y
Sbjct 4249 CAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIY 4308
Query 4307 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP 4366
CR ++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC +
Sbjct 4309 CRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDT 4366
Query 4367 LMQSADASTFLN 4378
+QS D + FLN
Sbjct 4367 TVQSKD-TNFLN 4377
Score = 303 bits (776), Expect = 4e-80, Method: Composition-based stats.
Identities = 182/971 (19%), Positives = 328/971 (34%), Gaps = 149/971 (15%)
Query 107 LVPHVGETPIAYRNVLLRKNGNKGA-------GGHSYGIDLKSYDLGDELGTDPIEDYEQ 159
+P I + LRK G KGA GG + + K D D + +P + +
Sbjct 176 FMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSK 235
Query 160 NWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYP---LDCIKDFLARAGKSMCTLS 216
L R G YVD C G L+ D + K++ +
Sbjct 236 KAYA---------LIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIW 286
Query 217 EQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSAK-----KFDTFKGEC 270
Q + +AW R + Q+ I+S D G
Sbjct 287 SQELPFD------------VTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSV 334
Query 271 ----PKFVFPLNSKVKVIQPRVEKKKTEGFMGR--IRSVYPVASPQECNNMHLSTLMKC- 323
P V+ +S + V+ + + Y V ++C + + C
Sbjct 335 VIKEPVHVYADDSIILRQHNLVDIMSCFYMEADAVVNAFYGVD-LKDCGFVMQFGYIDCE 393
Query 324 -NHCDEVSWQTCDFLKATCE-HCGTENLVIEGP-TTCGYLPTNAVVKMPCPACQDPEIGP 380
+ CD W + + CG + + G LP N V+
Sbjct 394 QDLCDFKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHT------------ 441
Query 381 EHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADI----GSGHT 436
S A Y ++ G FGGCV+ R W+P + + G +T
Sbjct 442 -KSAAGYGGFGCKDSFTLYGQTVVYFGGCVY----WSPARNIWIPILKSSVKSYDGLVYT 496
Query 437 GITGDNVETLNEDLL---EILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKS 493
G+ G +L+ L + + L + + + +++
Sbjct 497 GVVGCKAIVKETNLICKALYLDYVQHKCGNLHQRELLGVSDVWHKQLLLNRGVYKPLLEN 556
Query 494 LDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLD 553
+DY + + S + V + + R+ + G QA D
Sbjct 557 IDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSG---QAFC----------D 603
Query 554 AANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQWL 613
A+ + + +LD +D++ L + ++ +A Q
Sbjct 604 YADKICHAVVSKSKELLD-------VSLDSLSAAIHYLNSKIVDLA-----------QHF 645
Query 614 SNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
S+ + V K+ F+ L AW + L G + +V+ I NI
Sbjct 646 SDFGTSFVSKIVHFFKTF-----TTSTALAFAWVLFHVL-HGAYIVVESDIYFV-KNIPR 698
Query 674 CVKCFIDVVNKALEMCIDQVT---IAGAKLRSLNLGEVFIAQSK------GLYRQCIRGK 724
++ +D + I G + + ++ SK GL
Sbjct 699 YASAVAQAFRSVAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERGLLHSSQLPL 758
Query 725 EQLQLLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGT 781
+ L MP KA ++ +L+G D L V + L ++ V
Sbjct 759 DVYDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPC-----GYSEPPKVAD 813
Query 782 PVCV-NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-K 838
+C+ + + + + DK + + + +R+ + VTF E TV E+ K
Sbjct 814 KICIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAG--RRVTFKEQPTVNEIASTPK 871
Query 839 NVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDL---LTNMG 895
+++ +ELD+ + +LN C V+ V+ ++ EF VV +A+ + L P +L +
Sbjct 872 TIKVFYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVS 931
Query 896 IDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTED 955
L + + +LFD+AGEE +S++YC+F P EDD EE ++E T+
Sbjct 932 AFLQKLEDNSLFLFDEAGEEVLASKLYCAFTAP----EDDDFLEESGVEEDDVEGEETD- 986
Query 956 DYQGLPLEFGASAE-TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPV--NQFTGYLKL 1012
L ++ E V E+EE + L+DT + + EE V + F +
Sbjct 987 ------LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVEMSDFADLESV 1040
Query 1013 TDNVAIKCVDI 1023
+ C +
Sbjct 1041 IQDYENVCFEF 1051
Score = 176 bits (446), Expect = 9e-42, Method: Composition-based stats.
Identities = 51/156 (33%), Positives = 78/156 (50%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDILLAPLLS 1128
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + T QV + N++ ++ +
Sbjct 1392 AGIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFDLI 1427
Score = 47.7 bits (112), Expect = 0.006, Method: Composition-based stats.
Identities = 37/150 (25%), Positives = 60/150 (40%), Gaps = 16/150 (11%)
Query 1634 KFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILA 1693
+F +V L K NNC+L SVL +Q+L +F LQ+ + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1694 Y--SNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTL 1751
+N V + G V + L L + V C C L G++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1752 SYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
VS C CG L+ + F
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPF 1192
>sp|P0C6T9|R1A_CVBLU Replicase polyprotein 1a OS=Bovine coronavirus
(strain 98TXSF-110-LUN) OX=233264 GN=1a PE=3 SV=1
Length=4383
Score = 3563 bits (9238), Expect = 0.0, Method: Composition-based stats.
Identities = 1078/2892 (37%), Positives = 1615/2892 (56%), Gaps = 107/2892 (4%)
Query 1528 LSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPH 1587
++ ++K+L + + + TVD N + V + +G+ G + DG +VTK K
Sbjct 1552 ATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGENFGKSLGNVFCDGVNVTKHKCD 1607
Query 1588 VNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWA 1647
+N++GK FF + + +A D+ L Y + L + KW+ G + K A
Sbjct 1608 INYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQA 1667
Query 1648 DNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRE 1707
+NNC+++ L LQ L +KF QEA+ R+G A F +L+LA G+ D R+
Sbjct 1668 NNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRD 1727
Query 1708 TMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCG 1767
+ + +L A + CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG
Sbjct 1728 FLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCG 1786
Query 1768 RDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDG 1827
+ + V+ + F++ S PA KL +G AN + G+ + GHY H+ +++ D
Sbjct 1787 KKLI-HCVRFDVPFLICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDA 1843
Query 1828 AHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTE 1886
+++ K+++ G ++D Y K T +Y LD V E +P L YY YYT+
Sbjct 1844 SNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQ 1903
Query 1887 QPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDV 1944
+ I T + + NFKL D LN GF + E VT +P GDV
Sbjct 1904 RIIKAQFKTFEKVDGVYTNFKLI--GHTICDILNAKLGFDSSKEFVEYKVTEWPTATGDV 1961
Query 1945 VAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFE 2003
V Y +++G KP++W ++ + + + +P+ N F+
Sbjct 1962 VLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFD 2012
Query 2004 VLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKV 2063
VL V+D +++ + E E I+ ++ K +V +VI+ +K
Sbjct 2013 VLKVDDVDDGGDISESDAK----ESKEINIIKLSGVK---KPFKVEDSVIVNDDTSEIKY 2065
Query 2064 TQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFL 2123
+ L D+ ++ ++ N+LS+A+ + TI + V L
Sbjct 2066 VKSLSIVDVYDMWLTGCRYVVRTANDLSMAVNVPTIRKFIKFGMTLVSIPIDL-----LN 2120
Query 2124 GQAAITTSNCAKRLAQRV--FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVK 2181
+ N K + ++ N++ ++F LLF + + T +A K
Sbjct 2121 LREIKPVFNVVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---K 2173
Query 2182 SVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSY 2239
KL A N + K+S + A + + + + I F L G P++
Sbjct 2174 LTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTF 2233
Query 2240 CNGVRELYLNSSNVTT-------------MDFCEGSFPCSICLSGLDSLDSYPALETIQV 2286
+ + ++ ++ T +C GS C CL+G D LD+Y A++ +Q
Sbjct 2234 VGKIAQWIKSTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQY 2293
Query 2287 TISS--YKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLM 2342
+ +L + E +++Y L+T +FY L +Q+ + F+ ++ W +
Sbjct 2294 EADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSV 2353
Query 2343 WFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTT 2402
++S+ M P +R YI ASF ++ + H+ GC+ C+ CYKRNR+ RV+C+T
Sbjct 2354 RLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKPGCLFCYKRNRSLRVKCST 2413
Query 2403 IVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTD 2462
IV GM R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD
Sbjct 2414 IVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTD 2473
Query 2463 QSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDG 2522
+ + V V + L++++ GQ+TY+ S FV+ NL + KG ++V+V +
Sbjct 2474 VAYHTVTDVKQVGCYMRLFYERDGQRTYDDVNASLFVDYSNLLHSKVKGVPNMHVVVVEN 2533
Query 2523 KSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVP 2582
+ D++ +A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V
Sbjct 2534 DA--DKANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVD 2591
Query 2583 MEKLKALVATAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLE 2641
+ L AL+ATAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE
Sbjct 2592 KKSLNALIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLE 2651
Query 2642 VTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQ 2701
+T +SCNN + TY K +N+ DLG I +A+H+ VAK VS IW+V + LS
Sbjct 2652 LTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSD 2711
Query 2702 LRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAA 2761
+ +++ A K + +LT V+V+TT SLKGG + S + +L+C +
Sbjct 2712 FQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFLLSLVCFI-- 2769
Query 2762 LVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG- 2820
+ +MP +T+ D YK + +GV RD+ D CFANK FD W+ G
Sbjct 2770 -GLWCLMPTYTVHKSDFQLPVYTSYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGL 2828
Query 2821 -SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
Y N +CP+V A++ +++G V +P VLR LHF+ SA G CYTP
Sbjct 2829 SYYSNSMACPIVVAVVDQDLGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQ 2887
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SI 2938
I YS+F S CVL++ CT+F A G P PYCY L++ + YS L P RY L +
Sbjct 2888 ISYSNFYASGCVLSSACTMFAMADGSPQPYCYTEGLMQNASLYSSLVPHVRYNLANAKGF 2947
Query 2939 IQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGV 2998
I+FP EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG
Sbjct 2948 IRFPEVLREGLVRIVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGR 3007
Query 2999 DAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAAN 3058
D +LI +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N
Sbjct 3008 DVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVN 3067
Query 3059 ALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWIT 3118
+++ ++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W
Sbjct 3068 VIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFC 3127
Query 3119 AIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPL 3178
+Y+ + H W F +R+ + + TFEE AL TF++ K+ Y KL++ L
Sbjct 3128 LLYISVVVSNHAFWVFAYC--RRLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSD 3183
Query 3179 TQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDF-SNSGADVLYQPPQTSITSA 3237
+NRYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F +N+G+DVLYQPP S++++
Sbjct 3184 VAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTS 3243
Query 3238 VLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDL 3297
LQSG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +L
Sbjct 3244 FLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNL 3303
Query 3298 LIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLAC 3357
L R ++ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA
Sbjct 3304 LCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAA 3363
Query 3358 YNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 3417
YNG P G + MR ++TIKGSFL GSCGSVG+ + DCV F YMH +EL TG H GTD
Sbjct 3364 YNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVLMGDCVKFVYMHQLELSTGCHTGTDF 3423
Query 3418 EGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 3477
G FYGP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+
Sbjct 3424 NGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSN 3483
Query 3478 NYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVV 3537
+ + D V + L++ TG+++ + AA+K L +NG GR I+GS EDE TP DV
Sbjct 3484 GFSQVKSDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVY 3540
Query 3538 RQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA 3597
+Q +G+ Q K ++VKG W++ + I+ +W++F +V N L T +
Sbjct 3541 QQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALC 3599
Query 3598 IAACAMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRL 3656
+ + AMLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y
Sbjct 3600 VISLAMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTY 3658
Query 3657 KDCVMYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVI 3715
D V+Y L++ ++ +T R++ D + + VI++V Y G+ L++ I + ++
Sbjct 3659 TDEVIYGMLLLIGMVFVTLRSINHDLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLA 3716
Query 3716 SVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
S+ Y+ M A+ I V L F ++ +++ Y F+GY CY+GLF
Sbjct 3717 SLFGTYTWTTALSMAAAKVIA-KWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFS 3775
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
L+N FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+
Sbjct 3776 LMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQF 3835
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL
Sbjct 3836 QSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVL 3895
Query 3896 LSMQGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
+ AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G
Sbjct 3896 FANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARSSGS 3955
Query 3950 S-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQT 4008
+ + LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QT
Sbjct 3956 ANQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQT 4015
Query 4009 MLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTY 4068
MLF+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TY
Sbjct 4016 MLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 4075
Query 4069 ASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVAL 4126
A +W+IQ + D+D QL+EI S + WPL++ A R N SA LQNNEL P L
Sbjct 4076 AGNVWQIQTIQDSDGTNKQLNEI----SDDCNWPLVIIANRHNEVSATVLQNNELMPAKL 4131
Query 4127 RQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTEL 4186
+ +G QT T YYNNS G+ V A+LSD LK+ + K DG + EL
Sbjct 4132 KTQVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LEL 4188
Query 4187 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4246
+PPC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS
Sbjct 4189 DPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSL 4248
Query 4247 CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4306
CAF+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A +Q+S+GGAS C+Y
Sbjct 4249 CAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTNQDSYGGASVCIY 4308
Query 4307 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP 4366
CR ++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC +
Sbjct 4309 CRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDT 4366
Query 4367 LMQSADASTFLN 4378
+QS D + FLN
Sbjct 4367 TVQSKD-TNFLN 4377
Score = 303 bits (775), Expect = 4e-80, Method: Composition-based stats.
Identities = 182/971 (19%), Positives = 328/971 (34%), Gaps = 149/971 (15%)
Query 107 LVPHVGETPIAYRNVLLRKNGNKGA-------GGHSYGIDLKSYDLGDELGTDPIEDYEQ 159
+P I + LRK G KGA GG + + K D D + +P + +
Sbjct 176 FMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSK 235
Query 160 NWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYP---LDCIKDFLARAGKSMCTLS 216
L R G YVD C G L+ D + K++ +
Sbjct 236 KAYA---------LIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIW 286
Query 217 EQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSAK-----KFDTFKGEC 270
Q + +AW R + Q+ I+S D G
Sbjct 287 SQELPFD------------VTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSV 334
Query 271 ----PKFVFPLNSKVKVIQPRVEKKKTEGFMGR--IRSVYPVASPQECNNMHLSTLMKC- 323
P V+ +S + V+ + + Y V ++C + + C
Sbjct 335 VIKEPVHVYADDSIILRQHNLVDIMSCFYMEADAVVNAFYGVD-LKDCGFVMQFGYIDCE 393
Query 324 -NHCDEVSWQTCDFLKATCE-HCGTENLVIEGP-TTCGYLPTNAVVKMPCPACQDPEIGP 380
+ CD W + + CG + + G LP N V+
Sbjct 394 QDLCDFKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHT------------ 441
Query 381 EHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADI----GSGHT 436
S A Y ++ G FGGCV+ R W+P + + G +T
Sbjct 442 -KSAAGYGGFGCKDSFTLYGQTVVYFGGCVY----WSPARNIWIPILKSSVKSYDGLVYT 496
Query 437 GITGDNVETLNEDLL---EILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKS 493
G+ G +L+ L + + L + + + +++
Sbjct 497 GVVGCKAIVKETNLICKALYLDYVQHKCGNLHQRELLGVSDVWHKQLLLNRGVYKPLLEN 556
Query 494 LDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLD 553
+DY + + S + V + + R+ + G QA D
Sbjct 557 IDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSG---QAFC----------D 603
Query 554 AANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQWL 613
A+ + + +LD +D++ L + ++ +A Q
Sbjct 604 YADKICHAVVSKSKELLD-------VSLDSLSAAIHYLNSKIVDLA-----------QHF 645
Query 614 SNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
S+ + V K+ F+ L AW + L G + +V+ I NI
Sbjct 646 SDFGTSFVSKIVHFFKTF-----TTSTALAFAWVLFHVL-HGAYIVVESDIYFV-KNIPR 698
Query 674 CVKCFIDVVNKALEMCIDQVT---IAGAKLRSLNLGEVFIAQSK------GLYRQCIRGK 724
++ +D + I G + + ++ SK GL
Sbjct 699 YASAVAQAFRSVAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERGLLHSSQLPL 758
Query 725 EQLQLLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGT 781
+ L MP KA ++ +L+G D L V + L ++ V
Sbjct 759 DVYDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPC-----GYSEPPKVAD 813
Query 782 PVCV-NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-K 838
+C+ + + + + DK + + + +R+ + VTF E TV E+ K
Sbjct 814 KICIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAG--RRVTFKEQPTVNEIASTPK 871
Query 839 NVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDL---LTNMG 895
+++ +ELD+ + +LN C V+ V+ ++ EF VV +A+ + L P +L +
Sbjct 872 TIKVFYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVVDAIEEKLSPCKELEGVGAKVS 931
Query 896 IDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTED 955
L + + +LFD+AGEE +S++YC+F P EDD EE ++E T+
Sbjct 932 AFLQKLEDNSLFLFDEAGEEVLASKLYCAFTAP----EDDDFLEESGVEEDDVEGEETD- 986
Query 956 DYQGLPLEFGASAE-TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPV--NQFTGYLKL 1012
L ++ E V E+EE + L+DT + + EE V + F +
Sbjct 987 ------LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVEMSDFADLESV 1040
Query 1013 TDNVAIKCVDI 1023
+ C +
Sbjct 1041 IQDYENVCFEF 1051
Score = 176 bits (446), Expect = 9e-42, Method: Composition-based stats.
Identities = 51/156 (33%), Positives = 78/156 (50%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDILLAPLLS 1128
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + T QV + N++ ++ +
Sbjct 1392 AGIFSVPSDVSLTYLLGTAEKQVVLVSNNQEDFDLI 1427
Score = 47.7 bits (112), Expect = 0.006, Method: Composition-based stats.
Identities = 37/150 (25%), Positives = 60/150 (40%), Gaps = 16/150 (11%)
Query 1634 KFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILA 1693
+F +V L K NNC+L SVL +Q+L +F LQ+ + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1694 Y--SNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTL 1751
+N V + G V + L L + V C C L G++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1752 SYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
VS C CG L+ + F
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPF 1192
>sp|P0C6U7|R1A_CVHOC Replicase polyprotein 1a OS=Human coronavirus
OC43 OX=31631 GN=1a PE=1 SV=1
Length=4383
Score = 3541 bits (9183), Expect = 0.0, Method: Composition-based stats.
Identities = 1076/2892 (37%), Positives = 1605/2892 (55%), Gaps = 107/2892 (4%)
Query 1528 LSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPH 1587
++ ++K+L + + + TVD N + V + ++G+ G + DG +VTK K
Sbjct 1552 ATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCD 1607
Query 1588 VNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWA 1647
+N++GK FF + + +A D+ L Y + L + KW+ G + K A
Sbjct 1608 INYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYNMLVNCFKWQVVVNGKYFTFKQA 1667
Query 1648 DNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRE 1707
+NNC+++ L LQ L + F QEA+ R+G A F AL+LA G+ D R+
Sbjct 1668 NNNCFVNVSCLMLQSLHLTFKIVQWQEAWLEFRSGRPARFVALVLAKGGFKFGDPADSRD 1727
Query 1708 TMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCG 1767
+ + +L A + CK CG K TG++AVM+ GTLS ++L+ G ++ C CG
Sbjct 1728 FLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGLDAVMHFGTLSREDLEIGYTVDCSCG 1786
Query 1768 RDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDG 1827
+ + V+ + F++ S PA KL +G AN + G+ GHY H+ +++ D
Sbjct 1787 KKLI-HCVRFDVPFLICSNTPASVKLPKGVG-SANIFIGDN-VGHYVHVKCEQSYQLYDA 1843
Query 1828 AHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTE 1886
+++ K+++ G ++D Y K T +Y LD V E +P L YY YYT+
Sbjct 1844 SNVKKVTDVTGKLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQ 1903
Query 1887 QPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDV 1944
+ I T + + NFKL D LN GF + E +T +P GDV
Sbjct 1904 RIIKAQFKTFEKVDGVYTNFKLI--GHTVCDSLNSKLGFDSSKEFVEYKITEWPTATGDV 1961
Query 1945 VAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTS-NSFE 2003
V + Y +++G KP++W ++ + + + +P+ N F+
Sbjct 1962 VLANDDLYVKRYERGCITFGKPVIWLSHEKASLNSLT---------YFNRPLLVDDNKFD 2012
Query 2004 VLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKV 2063
VL V+D + + + E E I+ ++ K +V +VI+ K
Sbjct 2013 VLKVDDVDDSGDSSESGAK----ETKEINIIKLSGVK---KPFKVEDSVIVNDDTSETKY 2065
Query 2064 TQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFL 2123
+ L D+ ++ ++ N LS A+ + TI + V L
Sbjct 2066 VKSLSIVDVYDMWLTGCKYVVRTANALSRAVNVPTIRKFIKFGMTLVSIPIDL-----LN 2120
Query 2124 GQAAITTSNCAKRLAQR--VFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVK 2181
+ N K + + N++ ++F LLF + + T IA K
Sbjct 2121 LREIKPAVNVVKAVRNKTSACFNFIKWLFVLLFGWIKISADN----KVIYTTEIAS---K 2173
Query 2182 SVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSY 2239
KL A N + K+S + A + + + + I F L G P++
Sbjct 2174 LTCKLVALAFKNAFLTFKWSMVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTF 2233
Query 2240 CNGVRELYLNSSNVTT-------------MDFCEGSFPCSICLSGLDSLDSYPALETIQV 2286
+ + N+ ++ T +C GS C CL+G D LD+Y A++ +Q
Sbjct 2234 VGKIAQWIKNTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQY 2293
Query 2287 TISS--YKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLM 2342
+ +L + E +++Y L+T +FY L +Q+ + F+ ++ W
Sbjct 2294 EADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSF 2353
Query 2343 WFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTT 2402
++++ M P +R YI ASF ++ + H+ GC+ S C+ CYKRNR+ RV+C+T
Sbjct 2354 RLLVALANMLPAHVFMRFYIIIASFIKLFSLFKHVAYGCSKSGCLFCYKRNRSLRVKCST 2413
Query 2403 IVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTD 2462
IV GM R + V ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD
Sbjct 2414 IVGGMIRYYDVMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTD 2473
Query 2463 QSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDG 2522
+ + V V ++ L++D+ GQ+ Y+ S FV+ NL + K ++V+V +
Sbjct 2474 VAYHTVTDVKQVGCSMRLFYDRDGQRIYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVEN 2533
Query 2523 KSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVP 2582
+ D++ +A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V
Sbjct 2534 DA--DKANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVD 2591
Query 2583 MEKLKALVATAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLE 2641
+ L AL+ATAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE
Sbjct 2592 KKSLNALIATAHSSIKQGTQIYKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLE 2651
Query 2642 VTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQ 2701
+T +SCNN + TY K +N+ DLG I +A+H+ VAK VS IW+V + S
Sbjct 2652 LTDESCNNLVPTYLKSDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQFSSD 2711
Query 2702 LRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAA 2761
+ +++ A K + +LT V+V+TT SLKGG + S + +L+C +
Sbjct 2712 FQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLVCFI-- 2769
Query 2762 LVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG- 2820
+ +MP +T+ D YK + +GV RD+ D CFANK FD W+ G
Sbjct 2770 -GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGL 2828
Query 2821 -SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
Y N +CP+V A+I ++ G V +P VLR LHF+ SA G CYTP
Sbjct 2829 SYYSNSMACPIVVAVIDQDFGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQ 2887
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SI 2938
I YS+F S CVL++ CT+F A G P PYCY L++ + YS L P RY L +
Sbjct 2888 ISYSNFYASGCVLSSACTMFTMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGF 2947
Query 2939 IQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGV 2998
I+FP EG VRVV T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG
Sbjct 2948 IRFPEVLREGLVRVVRTRSMSYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGR 3007
Query 2999 DAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAAN 3058
D +LI +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y VV N
Sbjct 3008 DVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSVVFVN 3067
Query 3059 ALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWIT 3118
+++ ++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W
Sbjct 3068 VIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFC 3127
Query 3119 AIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPL 3178
+Y+ + H W F+ +++ + + TFEE AL TF++ K+ Y KL++ L
Sbjct 3128 LLYIAVVVSNHAFWVFSYC--RKLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSD 3183
Query 3179 TQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDF-SNSGADVLYQPPQTSITSA 3237
+NRYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F +N+G+DVLYQPP S++++
Sbjct 3184 VAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTS 3243
Query 3238 VLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDL 3297
LQSG KM P+ KVE C+V VT G TLNGLWLDD VYCPRHVIC+A DM NP+Y +L
Sbjct 3244 FLQSGIVKMVNPTSKVEPCVVSVTYGNMTLNGLWLDDKVYCPRHVICSASDMTNPDYTNL 3303
Query 3298 LIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLAC 3357
L R ++ F V + L V+ + M+ C+L L V N +TPKY F ++PG+TF+VLA
Sbjct 3304 LCRVTSSDFTVLFDRLSLTVMSYQMRGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAA 3363
Query 3358 YNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 3417
YNG P G + MR ++TIKGSFL GSCGSVG+ I DCV F YMH +EL TG H GTD
Sbjct 3364 YNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVGYVIMGDCVKFVYMHQLELSTGCHTGTDF 3423
Query 3418 EGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 3477
G FYGP+ D Q Q D ++N LAWLYAA++N WF+ ++ DFN+ A+
Sbjct 3424 NGDFYGPYKDAQVVQLPIQDYIQSVNFLAWLYAAILNNCNWFIQSDKCSVEDFNVWALSN 3483
Query 3478 NYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVV 3537
+ + D V + L++ TG+++ + AA+K L +NG GR I+GS EDE TP DV
Sbjct 3484 GFSQVKSDLV--IDALASMTGVSLETLLAAIKRL-KNGFQGRQIMGSCSFEDELTPSDVY 3540
Query 3538 RQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA 3597
+Q +G+ Q K ++ KGT W++ + I+ +W++F +V N T +
Sbjct 3541 QQLAGIKLQSKRTRLFKGTVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MFSITFCALC 3599
Query 3598 IAACAMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRL 3656
+ + AMLLVKHKH +L +++ P L T+ Y N +V ++ + WL S+ Y
Sbjct 3600 VISLAMLLVKHKHLYLTMYITPVLFTLLYNNYLVVYKHTFRGYVYAWLSYYVPSVE-YTY 3658
Query 3657 KDCVMYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVI 3715
D V+Y L++ ++ +T R++ D + + +I++ Y G+ L++ I + ++
Sbjct 3659 TDEVIYGMLLLVGMVFVTLRSINHDLFSFIMFVGRLISVFSLWYKGSNLEEEILL--MLA 3716
Query 3716 SVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
S+ Y+ M +A+ I V L F ++ ++L Y F+GY CY+GLF
Sbjct 3717 SLFGTYTWTTVLSMAVAKVIA-KWVAVNVLYFTDIPQIKIVLLCYLFIGYIISCYWGLFS 3775
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
L+N FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+
Sbjct 3776 LMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQF 3835
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D + AFEK+ LL VL
Sbjct 3836 QSKLTDVKCANVVLLNCLQHLHVASNSKLWHYCSTLHNEILATSDLSVAFEKLAQLLIVL 3895
Query 3896 LSMQGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
+ AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A +G
Sbjct 3896 FANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEARFSGS 3955
Query 3950 S-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQT 4008
+ + LK+L+K+ N+AKS ++RD A+ +KLE+MAD A+T MYK+AR DK++KV SA+QT
Sbjct 3956 ANQQQLKQLEKACNIAKSAYERDRAVAKKLERMADLALTNMYKEARINDKKSKVVSALQT 4015
Query 4009 MLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTY 4068
MLF+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TY
Sbjct 4016 MLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLNIIVPDKSVYDQIVDNIYVTY 4075
Query 4069 ASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVAL 4126
A +W+IQ + D+D QL+EI S + WPL++ A R N SA LQNNEL P L
Sbjct 4076 AGNVWQIQTIQDSDGTNKQLNEI----SDDCNWPLVIIANRYNEVSATVLQNNELMPAKL 4131
Query 4127 RQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTEL 4186
+ +G QT T YYNNS G+ V A+LSD LK+ + K DG + EL
Sbjct 4132 KIQVVNSGPDQTCNTPTQ--CYYNNSNNGKIVYAILSDVDGLKYTKILKDDGNFVV-LEL 4188
Query 4187 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4246
+PPC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS
Sbjct 4189 DPPCKFTVQDAKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSL 4248
Query 4247 CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4306
CAF+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+Y
Sbjct 4249 CAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIY 4308
Query 4307 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP 4366
CR ++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC +
Sbjct 4309 CRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCRVCGFWRDGSCSCVS-TDT 4366
Query 4367 LMQSADASTFLN 4378
+QS D + FLN
Sbjct 4367 TVQSKD-TNFLN 4377
Score = 295 bits (755), Expect = 9e-78, Method: Composition-based stats.
Identities = 182/970 (19%), Positives = 332/970 (34%), Gaps = 154/970 (16%)
Query 107 LVPHVGETPIAYRNVLLRKNGNKGA-------GGHSYGIDLKSYDLGDELGTDPIEDYEQ 159
+P I + LRK G KGA GG + D K D D++ +P + +
Sbjct 176 FMPVQSRKFIVPWVMYLRKRGEKGAYNKDHGCGGFGHVYDFKVEDAYDQVHDEPKGKFSK 235
Query 160 NWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYP---LDCIKDFLARAGKSMC-TL 215
L R G YVD C G L+ D + K++ T
Sbjct 236 KAYA---------LIRGYRGVKPLLYVDQYGCDYTGSLADGLEAYADKTLQEMKALFPTW 286
Query 216 SEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSAK-----KFDTFKGE 269
S++L + + +AW R + Q+ I S D G
Sbjct 287 SQELPF-------------DVIVAWHVVRDPRYVMRLQSAATICSVAYVANPTEDLCDGS 333
Query 270 C----PKFVFPLNSKVKVIQPRVEKKKTEGFMGR--IRSVYPVASPQECNNMHLSTLMKC 323
P V+ +S + + + + Y VA ++C + + C
Sbjct 334 VVIKEPVHVYADDSIILRQYNLFDIMSHFYMEADTVVNAFYGVA-LKDCGFVMQFGYIDC 392
Query 324 --NHCDEVSWQTCDFLKATCE-HCGTENLVIEG-PTTCGYLPTNAVVKMPCPACQDPEIG 379
+ CD W + + CG V + + G LP N V+
Sbjct 393 EQDSCDFKGWIPGNMIDGFACTTCGHVYEVGDLIAQSSGVLPVNPVLHT----------- 441
Query 380 PEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADIGS----GH 435
S A Y ++ G FGGCV+ R W+P + + S +
Sbjct 442 --KSAAGYGGFGCKDSFTLYGQTVVYFGGCVY----WSPARNIWIPILKSSVKSYDSLVY 495
Query 436 TGITGDNVETLNEDLL---EILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIK 492
TG+ G +L+ L + + L + + + ++
Sbjct 496 TGVLGCKAIVKETNLICKALYLDYVQHKCGNLHQRELLGVSDVWHKQLLINRGVYKPLLE 555
Query 493 SLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTL 552
++DY + + S + V + + R+ + G QA
Sbjct 556 NIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSG---QAFC---------- 602
Query 553 DAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQW 612
D A+ + + +LD +D++ L + ++ +A Q
Sbjct 603 DYADKLCHAVVSKSKELLD-------VSLDSLGAAIHYLNSKIVDLA-----------QH 644
Query 613 LSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIK 672
S+ + V K+ F+ L AW + L G + +V+ I NI
Sbjct 645 FSDFGTSFVSKIVHFFKTF-----TTSTALAFAWVLFHVL-HGAYIVVESDIYFV-KNIP 697
Query 673 DCVKCFIDVVNKALEMCIDQVT---IAGAKLRSLNLGEVFIAQSK------GLYRQCIRG 723
++ +D + I G + + ++ K GL
Sbjct 698 RYASAVAQAFQSVAKVVLDSLRVTFIDGLSCFKIGRRRICLSGRKIYEVERGLLHSSQLP 757
Query 724 KEQLQLLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
+ L MP KA ++ +L+G D L V + L ++ V
Sbjct 758 LDVYDLTMPSQVQKAKQKPIYLKGSGSDFSLADSVVEVVTTSLTPC-----GYSEPPKVA 812
Query 781 TPVCV-NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY- 837
+C+ + + + + DK + + + +R+ + VTF E TV E+
Sbjct 813 DKICIVDNVYMAKAGDKYYPVVVDDHVGLLDQAWRVPCAG--RRVTFKEQPTVKEIISMP 870
Query 838 KNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDL---LTNM 894
K +++ +ELD + +LN C V+ V+ ++ EF VV +A+ + L P +L +
Sbjct 871 KIIKVFYELDNDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKV 930
Query 895 GIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTE 954
L + +LFD+AGEE F+ ++YC+F P+++ + ++E+ E E
Sbjct 931 SAFLQKLEDNPLFLFDEAGEEVFAPKLYCAFTAPEDD---------DFLEESDVEEDDVE 981
Query 955 DDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKL-- 1012
+ L + A V E+EE + L+DT + + EE V + + ++ L
Sbjct 982 GEETDLTIT-SAGQPCVASEQEESSEVLEDTLDDGPSVETSDSQVEEDV-EMSDFVDLES 1039
Query 1013 ----TDNVAI 1018
+NV
Sbjct 1040 VIQDYENVCF 1049
Score = 174 bits (441), Expect = 3e-41, Method: Composition-based stats.
Identities = 51/156 (33%), Positives = 81/156 (52%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ + +K
Sbjct 1272 CITPNVCFVKGDIIKVSKLVKAEVVVNPANGHMVHGGGVAKAIAVAAGQQFVKETTNMVK 1331
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDILLAPLLS 1128
G G + +G L K L+VVGP+ + LL+ Y++FN+ D ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYVLLERVYKHFNNYDCVVTTLIS 1391
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + T + QV + N++ ++ +
Sbjct 1392 AGIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLI 1427
Score = 48.9 bits (115), Expect = 0.003, Method: Composition-based stats.
Identities = 37/150 (25%), Positives = 61/150 (41%), Gaps = 16/150 (11%)
Query 1634 KFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILA 1693
+F +V GL K NNC+L SVL +Q+L +F LQ+ + + + F ++
Sbjct 1057 EFVKVLGLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1694 Y--SNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTL 1751
+N + + G V + L L + V C C L G++A+ + G +
Sbjct 1117 KIPANIVLPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1752 SYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
VS C CG L+ + F
Sbjct 1173 --------VSHICKCGESMV--LIDVDVPF 1192
>sp|P0C6U0|R1A_CVBM Replicase polyprotein 1a OS=Bovine coronavirus
(strain Mebus) OX=11132 GN=1a PE=3 SV=1
Length=4383
Score = 3538 bits (9174), Expect = 0.0, Method: Composition-based stats.
Identities = 1075/2892 (37%), Positives = 1607/2892 (56%), Gaps = 107/2892 (4%)
Query 1528 LSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPH 1587
++ ++K+L + + + TVD N + V + ++G+ G + DG +VTK K
Sbjct 1552 ATVAQIKALF----LDKVDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCD 1607
Query 1588 VNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWA 1647
+N++GK FF + + +A D+ L Y + L + KW+ G + K A
Sbjct 1608 INYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQA 1667
Query 1648 DNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRE 1707
+NNC+++ L LQ L +KF QEA+ R+G A F +L+LA G+ D R+
Sbjct 1668 NNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRD 1727
Query 1708 TMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCG 1767
+ + +L A + CK CG K TGV+AVM+ GTLS ++L+ G ++ C CG
Sbjct 1728 FLRVVFSQVDLTGAICDFEIACK-CGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCG 1786
Query 1768 RDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDG 1827
+ + V+ + F++ S PA KL +G AN + G+ + GHY H+ +++ D
Sbjct 1787 KKLI-HCVRFDVPFLICSNTPASVKLPKGVG-SANIFKGD-KVGHYVHVKCEQSYQLYDA 1843
Query 1828 AHLTKMSEYKGPVTDVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTE 1886
+++ K+++ G ++D Y K T +Y LD V E +P L YY YYT+
Sbjct 1844 SNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQ 1903
Query 1887 QPIDL-VPTQPLPNASFDNFKLTCSNTKFADDLNQMTGF-TKPASRELSVTFFPDLNGDV 1944
+ I T + + NFKL D LN GF + E VT +P GDV
Sbjct 1904 RIIKAQFKTFEKVDGVYTNFKLI--GHTVCDILNAKLGFDSSKEFVEYKVTEWPTATGDV 1961
Query 1945 VAIDYRHYSASFKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDT-SNSFE 2003
V Y +++G KP++W ++ + + + +P+ N F+
Sbjct 1962 VLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLT---------YFNRPLLVDENKFD 2012
Query 2004 VLAVEDTQGMDNLACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKV 2063
VL V+D +++ + E E I+ ++ K +V +VI+ +K
Sbjct 2013 VLKVDDVDDGGDISESDAK----EPKEINIIKLSGVK---KPFKVEDSVIVNDDTSEIKY 2065
Query 2064 TQELGHEDLMAAYVENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFL 2123
+ L D+ ++ ++ N LS A+ + TI + V L
Sbjct 2066 VKSLSIVDVYDMWLTGCRCVVRTANALSRAVNVPTIRKFIKFGMTLVSIPIDL-----LN 2120
Query 2124 GQAAITTSNCAKRLAQRV--FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVK 2181
+ N K + ++ N++ ++F LLF + + T +A K
Sbjct 2121 LREIKPVFNVVKAVRNKISACFNFIKWLFVLLFGWIKISADN----KVIYTTEVAS---K 2173
Query 2182 SVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFG-VLLSNFG-APSY 2239
KL A N + K+S + A + + + + I F L G P++
Sbjct 2174 LTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTF 2233
Query 2240 CNGVRELYLNSSNVTT-------------MDFCEGSFPCSICLSGLDSLDSYPALETIQV 2286
+ + N+ ++ T +C GS C CL+G D LD+Y A++ +Q
Sbjct 2234 VGKIAQWIKNTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQY 2293
Query 2287 TISS--YKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLM 2342
+ +L + E +++Y L+T +FY L +Q+ + F+ ++ W +
Sbjct 2294 EADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSV 2353
Query 2343 WFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTT 2402
++S+ M P +R YI ASF ++ + H+ GC+ S C+ CYKRNR+ RV+C+T
Sbjct 2354 RLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCST 2413
Query 2403 IVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTD 2462
IV GM R + ANGG GFC H WNC++CD++ G+TFI+ E A DLS + KRPI PTD
Sbjct 2414 IVGGMIRYYDAMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTD 2473
Query 2463 QSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDG 2522
+ + V V + L++D+ GQ+TY+ S FV+ NL + K ++V+V +
Sbjct 2474 VAYHTVTDVKQVGCYMRLFYDRDGQRTYDDVNASLFVDYSNLLHSKVKSVPNMHVVVVEN 2533
Query 2523 KSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVP 2582
+ D++ +A+V+Y+Q + +PIL++D+ L++ T V+ MFD YVDTF + F V
Sbjct 2534 DA--DKANFLNAAVFYAQSLFRPILMVDKNLITTANTGTSVTETMFDVYVDTFLSMFDVD 2591
Query 2583 MEKLKALVATAHSELAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLE 2641
+ L AL+ATAHS + +G + VL TF+S AR+ +D+DVDTK + + + + + LE
Sbjct 2592 KKSLNALIATAHSSIKQGTQICKVLDTFLSCARKSCSIDSDVDTKCLADSVMSAVSAGLE 2651
Query 2642 VTGDSCNNFMLTYNKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQ 2701
+T +SCNN + TY K +N+ DLG I +A+H+ VAK VS IW+V + LS
Sbjct 2652 LTDESCNNLVPTYLKGDNIVAADLGVLIQNSAKHVQGNVAKIAGVSCIWSVDAFNQLSSD 2711
Query 2702 LRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAA 2761
+ +++ A K + +LT V+V+TT SLKGG + S + +L+C +
Sbjct 2712 FQHKLKKACCKTGLKLKLTYNKQMANVSVLTTPFSLKGGAVFSYFVYVCFVLSLVCFI-- 2769
Query 2762 LVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG- 2820
+ +MP +T+ D YK + +GV RD+ D CFANK FD W+ G
Sbjct 2770 -GLWCLMPTYTVHKSDFQLPVYASYKVLDNGVIRDVSVEDVCFANKFEQFDQWYESTFGL 2828
Query 2821 -SYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKL 2879
Y N +CP+V A++ ++ G V +P VLR LHF+ SA G CYTP
Sbjct 2829 SYYSNSMACPIVVAVVDQDFGSTVFNVPTKVLR-YGYHVLHFITHALSADGVQCYTPHSQ 2887
Query 2880 IEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDG-SI 2938
I YS+F S CVL++ CT+F A G P PYCY L++ + YS L P RY L +
Sbjct 2888 ISYSNFYASGCVLSSACTMFAMADGSPQPYCYTDGLMQNASLYSSLVPHVRYNLANAKGF 2947
Query 2939 IQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGV 2998
I+FP EG VR+V T YCR G CE ++ GIC + +G WVLNN++YR+L G FCG
Sbjct 2948 IRFPEVLREGLVRIVRTRSMPYCRVGLCEEADEGICFNFNGSWVLNNDYYRSLPGTFCGR 3007
Query 2999 DAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAAN 3058
D +LI +F L QPV L ++AS +AG I+A++V YY +K +R FG+Y +V N
Sbjct 3008 DVFDLIYQLFKGLAQPVDFLALTASSIAGAILAVIVVLVFYYLIKLKRAFGDYTSIVFVN 3067
Query 3059 ALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWIT 3118
+++ ++F +L + Y L VY++ Y Y T YF +++S + HLQW M+ I+P W
Sbjct 3068 VIVWCVNFMMLFVFQVYPTLSCVYAICYFYATLYFPSEISVIMHLQWLVMYGTIMPLWFC 3127
Query 3119 AIYVFCISLKHCHWFFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPL 3178
+Y+ + H W F+ +++ + + TFEE AL TF++ K+ Y KL++ L
Sbjct 3128 LLYISVVVSNHAFWVFSYC--RQLGTSVRSDGTFEEMALTTFMITKDSYCKLKNS--LSD 3183
Query 3179 TQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDF-SNSGADVLYQPPQTSITSA 3237
+NRYL+LYNKY+Y+SG +DT +YREAAC LAKA++ F +N+G+DVLYQPP S++++
Sbjct 3184 VAFNRYLSLYNKYRYYSGKMDTAAYREAACSQLAKAMDTFTNNNGSDVLYQPPTASVSTS 3243
Query 3238 VLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDL 3297
LQSG KM P+ KVE C+V VT G TLNGLWL D VYCPRHVIC+A DM NP+Y +L
Sbjct 3244 FLQSGIVKMVNPTSKVEPCIVSVTYGNMTLNGLWLGDKVYCPRHVICSASDMTNPDYTNL 3303
Query 3298 LIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLAC 3357
L R ++ F V + L V+ + MQ C+L L V N +TPKY F ++PG+TF+VLA
Sbjct 3304 LCRVTSSDFTVLFDRLSLTVMSYQMQGCMLVLTVTLQNSRTPKYTFGVVKPGETFTVLAA 3363
Query 3358 YNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDL 3417
YNG P G + MR ++TIKGSFL GSCGSV + I DCV F YMH +EL TG H GTD
Sbjct 3364 YNGKPQGAFHVTMRSSYTIKGSFLCGSCGSVVYVIMGDCVKFVYMHQLELSTGCHTGTDF 3423
Query 3418 EGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKY 3477
G FYGP+ D Q Q D ++N +AWLYAA++N WF+ ++ DFN+ A+
Sbjct 3424 NGDFYGPYKDAQVVQLPVQDYIQSVNFVAWLYAAILNNCNWFVQSDKCSVEDFNVWALSN 3483
Query 3478 NYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVV 3537
+ + D V + L++ TG+++ + AA+K L +NG GR I+GS EDE TP DV
Sbjct 3484 GFSQVKSDLV--IDALASMTGVSLETLLAAIKHL-KNGFQGRQIMGSCSFEDELTPSDVY 3540
Query 3538 RQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMA 3597
+Q +G+ Q K ++VKG W++ + I+ +W++F +V N L T +
Sbjct 3541 QQLAGIKLQSKRTRLVKGIVCWIMASTFLFSCIITAFVKWTMFMYVTTN-MLSITFCALC 3599
Query 3598 IAACAMLLVKHKHAFLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRL 3656
+ + MLLVKHKH +L ++++P L T+ Y N +V ++ + WL S+ Y
Sbjct 3600 VISLTMLLVKHKHLYLTMYIIPVLFTLLYNNYLVVYKQTFRGYVYAWLSYYVPSVE-YTY 3658
Query 3657 KDCVMYASALVL-LILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVI 3715
D V+Y L++ ++ +T R++ + + VI++V Y G+ L++ I + ++
Sbjct 3659 TDEVIYGMLLLIGMVFVTLRSINQYLFSFIMFVGRVISVVSLWYMGSNLEEEILL--MLA 3716
Query 3716 SVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFC 3775
S+ Y+ M A+ I V L F ++ +++ Y F+GY CY+GLF
Sbjct 3717 SLFGTYTWTTALSMAAAKVIA-KWVAVNVLYFTDIPQIKIVLVCYLFIGYIISCYWGLFS 3775
Query 3776 LLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATV 3835
L+N FR+ LGVY+Y +S QE RYMN+ GL PPK+S +A LN KLLGIGG P I+V+
Sbjct 3776 LMNSLFRMPLGVYNYKISVQELRYMNANGLRPPKNSFEALMLNFKLLGIGGVPIIEVSQF 3835
Query 3836 QSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVL 3895
QSK++DVKC +VVLL+ LQ L V S+SKLW C LHN+IL D AFEK+ LL VL
Sbjct 3836 QSKLTDVKCANVVLLNCLQHLHVASNSKLWQYCSTLHNEILATSDLGVAFEKLAQLLIVL 3895
Query 3896 LSMQGAVD------INRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD 3949
+ AVD I +C++ + LQA+ SEF ++ S+ Y A++ ++A ++G
Sbjct 3896 FANPAAVDSKCLTSIEEVCDDYAKDNTVLQALQSEFVNMASFVEYEVAKKNLDEACSSGS 3955
Query 3950 S-EVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQT 4008
+ + LK+L+K+ N+AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QT
Sbjct 3956 ANQQQLKQLEKACNIAKSAYERDRAVARKLERMADLALTNMYKEARINDKKSKVVSALQT 4015
Query 4009 MLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTY 4068
MLF+M+RKLDN ALN+I++NA GCVPLN IP A L ++VPD Y D TY
Sbjct 4016 MLFSMVRKLDNQALNSILDNAVKGCVPLNAIPSLAANTLTIIVPDKSVYDQVVDNVYVTY 4075
Query 4069 ASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRAN--SAVKLQNNELSPVAL 4126
A +W+IQ + D+D QL EI S + WPL++ A R N SA LQNNEL P L
Sbjct 4076 AGNVWQIQTIQDSDGTNKQLHEI----SDDCNWPLVIIANRHNEVSATALQNNELMPAKL 4131
Query 4127 RQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTEL 4186
+ +G QT T YYNNS G+ V A+LSD LK+ + K DG + EL
Sbjct 4132 KTQVVNSGPDQTCNTPTQ--CYYNNSYNGKIVYAILSDVDGLKYTKILKDDGNFVV-LEL 4188
Query 4187 EPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSF 4246
+PPC+F KG K+KYLYF+KG N L RG V+G++++TVRLQAG ATE +NS++LS
Sbjct 4189 DPPCKFTVQDVKGLKIKYLYFVKGCNTLARGWVVGTISSTVRLQAGTATEYASNSSILSL 4248
Query 4247 CAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLY 4306
CAF+VDP K Y D++ GG PI NCVKMLC H GTG AITV P+A Q+S+GGAS C+Y
Sbjct 4249 CAFSVDPKKTYLDFIQQGGTPIANCVKMLCDHAGTGMAITVKPDATTSQDSYGGASVCIY 4308
Query 4307 CRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP 4366
CR ++HP+ G C L+GK+VQ+P DPV + L + VC VCG W+ CSC +
Sbjct 4309 CRARVEHPDVDGLCKLRGKFVQVPVG-IKDPVSYVLTHDVCQVCGFWRDGSCSCVS-TDT 4366
Query 4367 LMQSADASTFLN 4378
+QS D + FLN
Sbjct 4367 TVQSKD-TNFLN 4377
Score = 301 bits (771), Expect = 1e-79, Method: Composition-based stats.
Identities = 182/970 (19%), Positives = 327/970 (34%), Gaps = 154/970 (16%)
Query 107 LVPHVGETPIAYRNVLLRKNGNKGA-------GGHSYGIDLKSYDLGDELGTDPIEDYEQ 159
+P I + LRK G KGA GG + + K D D + +P + +
Sbjct 176 FMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSK 235
Query 160 NWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYP---LDCIKDFLARAGKSMCTLS 216
L R G YVD C G L+ D + K++ +
Sbjct 236 KAYA---------LIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIW 286
Query 217 EQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKSAK-----KFDTFKGEC 270
Q + +AW R + Q+ I+S D G
Sbjct 287 SQELPFD------------VTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSV 334
Query 271 ----PKFVFPLNSKVKVIQPRVEKKKTEGFMGR--IRSVYPVASPQECNNMHLSTLMKC- 323
P V+ +S + V+ + + Y V ++C + + C
Sbjct 335 VIKEPVHVYADDSIILRQHNLVDIMSCFYMEADAVVNAFYGVD-LKDCGFVMQFGYIDCE 393
Query 324 -NHCDEVSWQTCDFLKATCE-HCGTENLVIEGP-TTCGYLPTNAVVKMPCPACQDPEIGP 380
+ CD W + + CG + + G LP N V+
Sbjct 394 QDLCDFKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHT------------ 441
Query 381 EHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADI----GSGHT 436
S A Y ++ G FGGCV+ R W+P + + G +T
Sbjct 442 -KSAAGYGGFGCKDSFTLYGQTVVYFGGCVY----WSPARNIWIPILKSSVKSYDGLVYT 496
Query 437 GITGDNVETLNEDLL---EILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKS 493
G+ G +L+ L + + L + + + +++
Sbjct 497 GVVGCKAIVKETNLICKALYLDYVQHKCGNLHQRELLGVSDVWHKQLLLNRGVYKPLLEN 556
Query 494 LDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLD 553
+DY + + S + V + + R+ + G QA D
Sbjct 557 IDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSG---QAFC----------D 603
Query 554 AANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQQTSQWL 613
A + + +LD +D++ L + ++ +A Q
Sbjct 604 YAGKICHAVVSKSKELLD-------VSLDSLGAAIHYLNSKIVDLA-----------QHF 645
Query 614 SNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKD 673
S+ + V K+ F+ L AW + L G + +V+ I NI
Sbjct 646 SDFGTSFVSKIVHFFKTF-----TTSTALAFAWVLFHVL-HGAYIVVESDIYFV-KNIPR 698
Query 674 CVKCFIDVVNKALEMCIDQVT---IAGAKLRSLNLGEVFIAQSK------GLYRQCIRGK 724
++ +D + I G + + ++ SK GL
Sbjct 699 YASAVAQAFRSVAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERGLLHSSQLPL 758
Query 725 EQLQLLMP---LKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGT 781
+ L MP K ++ +L+G D L V + L ++ V
Sbjct 759 DVYDLTMPSQVQKTKQKPIYLKGSGSDFSLADSVVEVVTTSLTPC-----GYSEPPKVAD 813
Query 782 PVCV-NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGY-K 838
+C+ + + + + DK + + + +R+ + VTF E TV E+ K
Sbjct 814 KICIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAG--RCVTFKEQPTVNEIASTPK 871
Query 839 NVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDL---LTNMG 895
+++ +ELD+ + +LN C V+ V+ ++ EF VV +A+ + L P +L +
Sbjct 872 TIKVFYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVS 931
Query 896 IDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTED 955
L + + +LFD+AGEE + ++YC+F P EDD EE ++E T+
Sbjct 932 AFLQKLEDNSLFLFDEAGEEVLAPKLYCAFTAP----EDDDFLEESGVEEDDVEGEETD- 986
Query 956 DYQGLPLEFGASAE-TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKL-- 1012
L ++ E V E+EE + L+DT + + EE V Q + ++ L
Sbjct 987 ------LTVTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDV-QMSDFVDLES 1039
Query 1013 ----TDNVAI 1018
+NV
Sbjct 1040 VIQDYENVCF 1049
Score = 176 bits (446), Expect = 8e-42, Method: Composition-based stats.
Identities = 51/156 (33%), Positives = 79/156 (51%), Gaps = 2/156 (1%)
Query 1011 KLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIK 1070
+T NV DI+K ++ V+VN AN H+ HGGGVA A+ A KE+ D +K
Sbjct 1272 CITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVK 1331
Query 1071 LNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDILLAPLLS 1128
G G + +G L K L+VVGP+ + LL+ Y++ N D ++ L+S
Sbjct 1332 SKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLIS 1391
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
AGIF SL + T + QV + N++ ++ +
Sbjct 1392 AGIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLI 1427
Score = 47.7 bits (112), Expect = 0.006, Method: Composition-based stats.
Identities = 37/150 (25%), Positives = 60/150 (40%), Gaps = 16/150 (11%)
Query 1634 KFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILA 1693
+F +V L K NNC+L SVL +Q+L +F LQ+ + + + F ++
Sbjct 1057 EFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVN 1116
Query 1694 Y--SNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTL 1751
+N V + G V + L L + V C C L G++A+ + G +
Sbjct 1117 KIPANIVVPQGGYVADFAYWFL---TLCDWQCVAYWKCIKCDL-ALKLKGLDAMFFYGDV 1172
Query 1752 SYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
VS C CG L+ + F
Sbjct 1173 --------VSHVCKCGESMV--LIDVDVPF 1192
>sp|P0C6U4|R1A_CVHN2 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N2) OX=443240 GN=1a PE=3 SV=1
Length=4441
Score = 3486 bits (9039), Expect = 0.0, Method: Composition-based stats.
Identities = 1050/2937 (36%), Positives = 1581/2937 (54%), Gaps = 110/2937 (4%)
Query 1488 RDWSYSGQ----RTELGVEFLKRGDKIVYHTLESPVEFHLDGEV--LSLDKLKSLLSLRE 1541
+DW + V++ + + I + + DG +++++ LL
Sbjct 1563 KDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLL---- 1618
Query 1542 VKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSD 1601
K I V TVD N + + + +G+ G + DG DVTK+K + K + +
Sbjct 1619 AKKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENL 1678
Query 1602 DTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
A + D+ L Y + L KW G S + + NNCY++ L LQ
Sbjct 1679 SLADISAVQSSFGFDQQQLLAYYNFL-TVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQ 1737
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
+ +KFN QEA+Y RAG AL+LA + E D + + +L+ A+L A
Sbjct 1738 HINLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGA 1797
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
L ++C CG K + GV+AVM+ GTL+ +L G I C C + + F
Sbjct 1798 ICELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAG-RIVHCTKLNVPF 1855
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S P L + AN + G GHYTH+ D + K + G +T
Sbjct 1856 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1913
Query 1842 DVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLPN 1899
D Y K + T T +Y LD V P L YY + YYT+ I +
Sbjct 1914 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYTKPIIKAQFKPFAKVD 1973
Query 1900 ASFDNFKLTCSNTKFADDLNQMTGFTKP-ASRELSVTFFPDLNGDVVAIDYRHYSASFKK 1958
+ NFKL + LN GF E VT +P GDVV Y + K
Sbjct 1974 GVYTNFKLVGHD--ICAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2031
Query 1959 GAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKP-VDTSNSFEVLAVEDTQGMDNLA 2017
G + KP++W + + + + KP + N + VL+V+ +
Sbjct 2032 GCETFGKPVIWLCHDEASLNSLT---------YFNKPSFKSENRYSVLSVDSV------S 2076
Query 2018 CESQQPTSEEVVENPTIQKEV-IECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAY 2076
ESQ V+E+ KEV ++ KT ++ +I+ + +KV + L D+ Y
Sbjct 2077 EESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDMY 2136
Query 2077 VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKR 2136
+ + NELS + T+ + I + L ++ Q + R
Sbjct 2137 LTGCDYVVWVANELSRLVKSPTVREYIRYGIKPITIPIDLLCLRD-DNQTLLVPKIFKAR 2195
Query 2137 LAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVK 2196
+ F ++ ++F +F L FT T IA ++ L L +
Sbjct 2196 AIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAFQTFR 2249
Query 2197 SPKFSKLFTIAMWLLLLSICLGSLICVTAAFG----------------VLLSNFGAPSYC 2240
F K F + + L + + + F + + FG + C
Sbjct 2250 WSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTIC 2309
Query 2241 NGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL--DLTIL 2298
+ +L + T FC GSF C +C SG D LD+Y A++ +Q + L ++++
Sbjct 2310 DFYSKLGVG----FTSHFCNGSFICELCYSGFDMLDTYAAIDFVQYEVDRRVLFDYVSLV 2365
Query 2299 GLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSA 2356
L E V+ Y L+T +FY L +Q+F + F+ + WL+ FI+ + M P
Sbjct 2366 KLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAFV 2425
Query 2357 MVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYAN 2416
++R YI + Y + HI+ GC + C+ CYKRN + RV+C+TIV G+ R + + AN
Sbjct 2426 LLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITAN 2485
Query 2417 GGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNG 2476
GG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2486 GGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVGC 2545
Query 2477 ALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASV 2536
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + + D + +A V
Sbjct 2546 MMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDA--DRANFLNAVV 2603
Query 2537 YYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSE 2596
+Y+Q + +PILL+D+ L++ + V+ MFD YVDTF + F V + V AH+
Sbjct 2604 FYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVNIAHAS 2663
Query 2597 LAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYN 2655
L +GV L+ VL TFV R+ +D+DV+T+ + + + + + LE T ++ NN + TY
Sbjct 2664 LREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVPTYL 2723
Query 2656 KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNI 2715
K +N+ DLG I A+H+ VAK+ N+S IW + + L+ L+ +++ A K +
Sbjct 2724 KSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDTFNQLTADLQHKLKKACVKTGL 2783
Query 2716 PFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSI 2775
+LT V ++TT SLKGG ++S ++ +L+C + + + ++P +++
Sbjct 2784 KLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPTYSVYK 2840
Query 2776 HDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAA 2833
D + +K I +GV RDI D CFANK FD W+ G Y N CP+V A
Sbjct 2841 SDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSFYYHNSMDCPIVVA 2900
Query 2834 IITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLA 2893
++ +IG + +P VLR LHFL F++ CYTP I Y+DF S CVL+
Sbjct 2901 VMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVLS 2959
Query 2894 AECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRV 2952
+ CT+FK G P PYCY +++ + Y+ L P TRY L + + I+FP+ EG VR+
Sbjct 2960 SLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVRI 3019
Query 2953 VTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLV 3012
V T YCR G CE +E GIC + + WVLNN++YR++ G FCG D +L F+ L+
Sbjct 3020 VRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQFFSSLI 3079
Query 3013 QPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLV 3072
+P+ ++AS + G I+AI+V YY +K +R FG+Y VV N +++ ++F +L +
Sbjct 3080 RPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVF 3139
Query 3073 PAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHW 3132
Y VY+ FY Y+T YF +++S + HLQW M+ I+PFW YV + H W
Sbjct 3140 QVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVLW 3199
Query 3133 FFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYK 3192
F+ +++ N STFEE +L TF++ K+ Y +L++ + YNRYL+LYNKY+
Sbjct 3200 LFSYC--RKIGVNVCNDSTFEETSLTTFMITKDSYCRLKNS--VSDVAYNRYLSLYNKYR 3255
Query 3193 YFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSG 3251
Y+SG +DT +YREAAC LAKA+ F+ N+G DVLYQPP S++++ LQSG KM P+
Sbjct 3256 YYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPTS 3315
Query 3252 KVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAG 3311
K+E C+V VT G+ TLNGLWLDD VYCPRHVIC + +M P+Y LL R + F + +G
Sbjct 3316 KIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDFTIMSG 3375
Query 3312 NVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMR 3371
+ L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + MR
Sbjct 3376 RMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAFHVTMR 3435
Query 3372 PNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTA 3431
++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q
Sbjct 3436 SSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYRDAQVV 3495
Query 3432 QAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILG 3491
Q D T+NV+AWLYAA++N WF+ ++ DFN+ AM + + D V L
Sbjct 3496 QLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADLV--LD 3553
Query 3492 PLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKK 3551
L++ TG+++ + AA+K L G GR ILGS EDE P DV +Q +GV Q K K+
Sbjct 3554 ALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTKR 3612
Query 3552 IVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHA 3611
+K T +W+L++ I+ +W++F ++ + + TL ++ + MLLVKHKH
Sbjct 3613 FIKETIYWILISTFLFSCIISAFVKWTIFMYINTH-MIGVTLCVLCFVSFMMLLVKHKHF 3671
Query 3612 FLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLI 3670
+L ++++P L T+ Y N +V + WL +++ + + V I
Sbjct 3672 YLTMYIIPVLCTLFYVNYLVVYKEGFRGLTYVWLSYFVPAVNFTYVYEVFYGCILCVFAI 3731
Query 3671 LMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMF 3730
+T ++ D ++ + ++TL+ Y+G+ L++ + ++ + + Y+ +
Sbjct 3732 FITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTWTTILSLA 3789
Query 3731 LARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDY 3790
+A+ IV + F ++ I+L Y F+GY CY+G F LLN FR+ +GVY+Y
Sbjct 3790 IAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMGVYNY 3848
Query 3791 LVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLL 3850
+S QE RYMN+ GL PP++S +A LN+KLLGIGG P I+V+ +QSK++DVKC +VVLL
Sbjct 3849 KISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCANVVLL 3908
Query 3851 SVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------I 3904
+ LQ L V S+S+LW C LHN+IL D + AF+K+ LL VL + AVD I
Sbjct 3909 NCLQHLHVASNSRLWQYCSILHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDTKCLASI 3968
Query 3905 NRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNV 3963
+ + ++ + + LQA+ SEF ++ S+ Y A++ A +G ++ +K+L+K+ N+
Sbjct 3969 DEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNI 4028
Query 3964 AKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALN 4023
AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN
Sbjct 4029 AKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALN 4088
Query 4024 NIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADS 4083
+I++NA GCVPLN IP A L +++PD + D YA ++W IQ V DAD
Sbjct 4089 SILDNAVKGCVPLNAIPALAANTLTIIIPDKQVFDKVVDNVYVAYAGSVWHIQTVQDADG 4148
Query 4084 KIVQLSEINMDNSPNLAWPLIVTALRANS--AVKLQNNELSPVALRQMSCAAGTTQTACT 4141
QL++I++D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4149 INKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDMNCNI 4204
Query 4142 DDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPK 4201
YYNN GR V A+LSD LK+ + K DG + EL+PPC+F KG K
Sbjct 4205 PTQ--CYYNNGSSGRIVYAVLSDVDGLKYTKIIKDDGNCVV-LELDPPCKFSIQDVKGLK 4261
Query 4202 VKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYL 4261
+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VDP K Y DY+
Sbjct 4262 IKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKTYLDYI 4321
Query 4262 ASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCD 4321
GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+ G C
Sbjct 4322 QQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDVDGLCK 4381
Query 4322 LKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
L+GK+VQ+P DP+ + L + VC VCG W+ CSC +QS D FLN
Sbjct 4382 LRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG-SGVAVQSKD-LNFLN 4435
Score = 274 bits (700), Expect = 3e-71, Method: Composition-based stats.
Identities = 150/930 (16%), Positives = 296/930 (32%), Gaps = 148/930 (16%)
Query 141 KSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPLDC 200
+D D D + K+ A L R+ G +VD C G DC
Sbjct 185 FKFDDYDFSVEDAYAEVHAEPKGKYSQKAYA-LLRQYRGIKPVLFVDQYGCDYSGKLADC 243
Query 201 IKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKS 259
A S+ + ++ + +AW R + QT I
Sbjct 244 ---LQAYGHYSLQDMRQKQSVWLANCDFDIV------VAWHVVRDSRFVMRLQTIATICG 294
Query 260 AKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNNMHLST 319
K + + V ++ K M V +++
Sbjct 295 IKYVAQPTEDVVDGAVVIREPVHLLSADAIVLKLPSLM----KVMTHMDDFSIKSIYNVD 350
Query 320 LMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYLPTNAVVKMPCPACQDPEIG 379
L C + + C +N G + + + C D
Sbjct 351 LCDCGFVMQYGYV----------DCFNDNCDFYGWVSGNMM--DGFSCPLCCTVYDSSEV 398
Query 380 PEHS---VADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADIGSGHT 436
S + + T +G V G YW PR
Sbjct 399 KAQSSGVIPENPVLFTNSTDTVNPDSFNLYGYSV-TPFGSC---IYWSPRP--------- 445
Query 437 GITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDY 496
G+ +++ + ++ + + S +T
Sbjct 446 GLWIPIIKSSVKSYDDL----------------------VYSGVVGCKSIVKETALITHA 483
Query 497 KSFKTIVESCGNYKVTKGKPVKGAW------NIGQQRSVLTPLCGFPSQAAGVIR--SIF 548
+ CGN + V +W N G +L + F + A ++
Sbjct 484 LYLDYVQCKCGNLEQNHILGVNNSWCRQLLLNRGDYNMLLKNIDLFVKRRADFACKFAVC 543
Query 549 ARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYT-------SDLLTNSVIIMAYV 601
+LDG+ +S L+ + ++ S +++ + M +
Sbjct 544 GDGF-------------VPFLLDGLIPRSYYLIQSGIFFTSLMSQFSQEVSDMCLKMCIL 590
Query 602 TGGLVQQTSQWLSNLLGTTVEK--------LRPIFEWIEAKLSAGVEFLKDAWEILKFLI 653
V + ++ + + V + + + W L A W + + L+
Sbjct 591 FMDRVSVATFYIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDASAP--ATGWLLYQ-LL 647
Query 654 TGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAK----LRSLNL---- 705
G+F + + + I D K ++ ++ ++ VT+ K L+++N
Sbjct 648 NGLFVVSQANFNFVA-LIPDYAKILVNKFYTFFKLLLECVTVDVLKDMPVLKTINGLVCI 706
Query 706 -GEVFIAQSKGLYRQCIRGKEQLQLLMPLKA-PKEVTFLEGDSHDTVLTSEEVVLKNGEL 763
G F S GL ++P A +++ F EG +E V++++ +
Sbjct 707 VGNKFYNVSTGLI---------PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVI 750
Query 764 EALETPVDSFT---NGAIVGTPVCVNGLMLLEIKDKEQYCALSP-GLLATNNVFRLKGGA 819
E +++ + S+ V ++ + + + DK ++ + + +R
Sbjct 751 ENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGDKFFPIVMNDKNICLLDQAWRFPCAG 810
Query 820 PIKGVTFGED-TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAE 878
+ V F E V E+ V++ F+LD D +L + CS + VE G V +F VV +
Sbjct 811 --RKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCD 868
Query 879 AVVKTLQPVSD---LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDD 935
A+ L D + + L++ + YLFD+AG+E +SRMYC+F D E+
Sbjct 869 AIENALNSCKDHPVVGYQVRAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVIS 928
Query 936 AECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEP-- 993
+E E+ ID E ++D + E V + ++ED + + ++
Sbjct 929 SEAVEDTIDGVVEDTINDDEDVVTGDND----DEDVVTGDNDDEDVVTGDNDDEDVVTGD 984
Query 994 -EPEPTPEEPVNQFTGYLKLTDNVAIKCVD 1022
+ E + D+ + D
Sbjct 985 NDDEDVVTGDNDDEDVVTGDNDDEDVVTGD 1014
Score = 172 bits (436), Expect = 1e-40, Method: Composition-based stats.
Identities = 55/157 (35%), Positives = 79/157 (50%), Gaps = 2/157 (1%)
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
L +T NV DI+ A+ VIVN AN H+ HGGGVA A+ A KE+ +
Sbjct 1328 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1387
Query 1070 KLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDILLAPLL 1127
K G VG + +G L K L++VGP+ + LL AY++ N+ D L+ L+
Sbjct 1388 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1447
Query 1128 SAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
SAGIF SL + V QV + N+K ++ +
Sbjct 1448 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDII 1484
Score = 52.4 bits (124), Expect = 2e-04, Method: Composition-based stats.
Identities = 48/205 (23%), Positives = 76/205 (37%), Gaps = 18/205 (9%)
Query 1573 PTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTL----DESFLGRYMSALN 1628
D +I N + DD F+ Y L D ++S +
Sbjct 1049 DVVTGDNDDEEIVTGDNDDQIVVTGDDVDDIESVYDFDTYKALLVFNDVYNDALFVSYGS 1108
Query 1629 HTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFC 1688
+ + +V GL S NC+L SVLL +Q+L KF A++ + + G +F
Sbjct 1109 SVETETYFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFV 1168
Query 1689 ALILAYSNKTVGEL--GDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVM 1746
+L K + G V + L ++ N C CG + L G++AV
Sbjct 1169 DYLLTTIPKAIVLPQGGYVADFAYWFLNQFDI---NAYANWCCLKCGF-SFDLNGLDAVF 1224
Query 1747 YMGTLSYDNLKTGVSIPCVCGRDAT 1771
+ G + VS C CG + T
Sbjct 1225 FYGDI--------VSHVCKCGHNMT 1241
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 25/157 (16%), Positives = 44/157 (28%), Gaps = 15/157 (10%)
Query 1194 EKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMS 1253
+V D+ + +V +L + + + E +
Sbjct 1331 TPNVCFVKGDIINVARLVKADVIVNPANGH-----MLHGGGVAKAIAVAAGKKFSKETAA 1385
Query 1254 FLEKDAPYMVGDVITSGD------ITCVVIPSKKAGGTTE--MLSRALKKVPVDEYITTY 1305
++ VGD S I +V P + G +L+RA K ++ Y
Sbjct 1386 MVKSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKH--LNNYDCCL 1443
Query 1306 PGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEE 1342
AG A +L N KE+
Sbjct 1444 STLISAGIFSVPADVSLTYLLGVVDKQVILVSNNKED 1480
>sp|P0C6U5|R1A_CVHN5 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N5) OX=443241 GN=1a PE=3 SV=1
Length=4421
Score = 3482 bits (9030), Expect = 0.0, Method: Composition-based stats.
Identities = 1049/2937 (36%), Positives = 1580/2937 (54%), Gaps = 110/2937 (4%)
Query 1488 RDWSYSGQ----RTELGVEFLKRGDKIVYHTLESPVEFHLDGEV--LSLDKLKSLLSLRE 1541
+DW + V++ + + I + + DG +++++ LL
Sbjct 1543 KDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLL---- 1598
Query 1542 VKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSD 1601
K I V TVD N + + + +G+ G + DG DVTK+K + K + +
Sbjct 1599 AKKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENL 1658
Query 1602 DTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
A + D+ L Y + L KW G S + + NNCY++ L LQ
Sbjct 1659 SLADISAVQSSFGFDQQQLLAYYNFL-TVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQ 1717
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
+ +KFN QEA+Y RAG AL+LA + E D + + +L+ A+L A
Sbjct 1718 HINLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGA 1777
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
L ++C CG K + GV+AVM+ GTL+ +L G I C C + + F
Sbjct 1778 ICELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAG-RIVHCTKLNVPF 1835
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S P L + AN + G GHYTH+ D + K + G +T
Sbjct 1836 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1893
Query 1842 DVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLPN 1899
D Y K + T T +Y LD V P L YY + YYT+ I +
Sbjct 1894 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYTKPIIKAQFKPFAKVD 1953
Query 1900 ASFDNFKLTCSNTKFADDLNQMTGFTKP-ASRELSVTFFPDLNGDVVAIDYRHYSASFKK 1958
+ NFKL + LN GF E VT +P GDVV Y + K
Sbjct 1954 GVYTNFKLVGHD--ICAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2011
Query 1959 GAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKP-VDTSNSFEVLAVEDTQGMDNLA 2017
G + KP++W + + + + KP + N + VL+V+ +
Sbjct 2012 GCETFGKPVIWFCHDEASLNSLT---------YFNKPSFKSENRYSVLSVDSV------S 2056
Query 2018 CESQQPTSEEVVENPTIQKEV-IECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAY 2076
ESQ V+E+ KEV ++ KT ++ +I+ + +KV + L D+ Y
Sbjct 2057 EESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDMY 2116
Query 2077 VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKR 2136
+ + NELS + T+ + I + L ++ Q + R
Sbjct 2117 LTGCDYVVWVANELSRLVKSPTVREYIRYGIKPITIPIDLLCLRD-DNQTLLVPKIFKAR 2175
Query 2137 LAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVK 2196
+ F ++ ++F +F L FT T IA ++ L L +
Sbjct 2176 AIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAFQTFR 2229
Query 2197 SPKFSKLFTIAMWLLLLSICLGSLICVTAAFG----------------VLLSNFGAPSYC 2240
F K F + + L + + + F + + FG + C
Sbjct 2230 WSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTIC 2289
Query 2241 NGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL--DLTIL 2298
+ +L + T FC GSF C +C SG D LD+Y A++ +Q + L ++++
Sbjct 2290 DFYSKLGVG----FTSHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDYVSLV 2345
Query 2299 GLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSA 2356
L E V+ Y L+T +FY L +Q+F + F+ + WL+ FI+ + M P
Sbjct 2346 KLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAFV 2405
Query 2357 MVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYAN 2416
++R YI + Y + HI+ GC + C+ CYKRN + RV+C+TIV G+ R + + AN
Sbjct 2406 LLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITAN 2465
Query 2417 GGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNG 2476
GG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2466 GGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVGC 2525
Query 2477 ALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASV 2536
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + + D + +A V
Sbjct 2526 MMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDA--DRANFLNAVV 2583
Query 2537 YYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSE 2596
+Y+Q + +PILL+D+ L++ + V+ MFD YVDTF + F V + V AH+
Sbjct 2584 FYAQSLYRPILLVDKKLITTACNGISVTQIMFDVYVDTFMSHFDVDRKSFNNFVNIAHAS 2643
Query 2597 LAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYN 2655
L +GV L+ VL TFV R+ +D+DV+T+ + + + + + LE T ++ NN + TY
Sbjct 2644 LREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVPTYL 2703
Query 2656 KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNI 2715
K +N+ DLG I A+H+ VAK N+S IW + + L+ L+ +++ A K +
Sbjct 2704 KSDNIVAADLGVLIQNGAKHVQGNVAKVANISCIWFIDAFNQLTADLQHKLKKACVKTGL 2763
Query 2716 PFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSI 2775
+LT V ++TT SLKGG ++S ++ +L+C + + + ++P +++
Sbjct 2764 KLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFISLICFI---LLWALLPTYSVYK 2820
Query 2776 HDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAA 2833
D + +K I +GV RDI D CFANK FD W+ G Y N CP+V A
Sbjct 2821 SDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDCPIVVA 2880
Query 2834 IITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLA 2893
++ +IG + +P VLR LHFL F++ CYTP I Y+DF S CVL+
Sbjct 2881 VMDEDIGSTMFNVPTKVLR-YGFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVLS 2939
Query 2894 AECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRV 2952
+ CT+FK G P PYCY +++ + Y+ L P TRY L + + I+FP+ EG VR+
Sbjct 2940 SLCTMFKRGDGTPHPYCYTDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVRI 2999
Query 2953 VTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLV 3012
V T YCR G CE +E GIC + + WVLNN++YR++ G FCG D +L F+ L+
Sbjct 3000 VRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDFFDLFYQFFSSLI 3059
Query 3013 QPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLV 3072
+P+ ++AS + G I+AI+V YY +K +R FG+Y VV N +++ ++F +L +
Sbjct 3060 RPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVIVWCINFLMLFVF 3119
Query 3073 PAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHW 3132
Y VY+ FY Y+T YF +++S + HLQW M+ I+PFW YV + H W
Sbjct 3120 QVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVLW 3179
Query 3133 FFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYK 3192
F+ +++ N + STFEE +L TF++ K+ Y +L++ + YNRYL+LYNKY+
Sbjct 3180 LFSYC--RKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNS--VSDVAYNRYLSLYNKYR 3235
Query 3193 YFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSG 3251
Y+SG +DT +YREAAC LAKA+ F+ N+G DVLYQPP S++++ LQSG KM P+
Sbjct 3236 YYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPTS 3295
Query 3252 KVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAG 3311
K+E C+V VT G+ TLNGLWLDD VYCPRHVIC + +M P+Y LL R + F + +G
Sbjct 3296 KIEPCLVSVTYGSMTLNGLWLDDKVYCPRHVICLSSNMNEPDYSALLCRVTLGDFTIMSG 3355
Query 3312 NVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMR 3371
+ L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + MR
Sbjct 3356 RMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGVVKPGETFTVLAAYNGRPQGAFHVTMR 3415
Query 3372 PNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTA 3431
++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q
Sbjct 3416 SSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFNGNFYGPYRDAQVV 3475
Query 3432 QAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILG 3491
Q D T+NV+AWLYAA++N WF+ ++ DFN+ AM + + D V L
Sbjct 3476 QLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSIEDFNVWAMTNGFSQVKADLV--LD 3533
Query 3492 PLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKK 3551
L++ TG+++ + AA+K L G GR ILGS EDE P DV +Q +GV Q K K+
Sbjct 3534 ALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTKR 3592
Query 3552 IVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHA 3611
+K T +W+L++ I+ +W++F ++ + + TL ++ + MLLVKHKH
Sbjct 3593 FIKETIYWILISTFLFSCIISAFVKWTIFMYINTH-MIGVTLCVLCFVSFMMLLVKHKHF 3651
Query 3612 FLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLI 3670
+L ++++P L T+ Y N +V + WL +++ + + V I
Sbjct 3652 YLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSHFVPAVNFTYVYEVFYGCILCVFAI 3711
Query 3671 LMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMF 3730
+T ++ D ++ + ++TL+ Y+G+ L++ + ++ + + Y+ +
Sbjct 3712 FITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTWTTILSLA 3769
Query 3731 LARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDY 3790
+A+ IV + F ++ I+L Y F+GY CY+G F LLN FR+ +GVY+Y
Sbjct 3770 IAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMGVYNY 3828
Query 3791 LVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLL 3850
+S QE RYMN+ GL PP++S +A LN+KLLGIGG P I+V+ +QSK++DVKC +VVLL
Sbjct 3829 KISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCANVVLL 3888
Query 3851 SVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------I 3904
+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL S AVD I
Sbjct 3889 NCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFSNPAAVDTKCLASI 3948
Query 3905 NRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNV 3963
+ + ++ + + LQA+ SEF ++ S+ Y A++ A +G ++ +K+L+K+ N+
Sbjct 3949 DEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNI 4008
Query 3964 AKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALN 4023
AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN
Sbjct 4009 AKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALN 4068
Query 4024 NIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADS 4083
+I++NA GCVPL+ IP A L +++PD + D TYA ++W IQ V DAD
Sbjct 4069 SILDNAVKGCVPLSAIPALAANTLTIIIPDKQVFDKVVDNVYVTYAGSVWHIQTVQDADG 4128
Query 4084 KIVQLSEINMDNSPNLAWPLIVTALRANS--AVKLQNNELSPVALRQMSCAAGTTQTACT 4141
QL++I++D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4129 INKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDINCNI 4184
Query 4142 DDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPK 4201
YYNN GR V A+LSD LK+ + K DG + EL+PPC+F KG K
Sbjct 4185 PTQ--CYYNNVSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFSIQDVKGLK 4241
Query 4202 VKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYL 4261
+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VDP K Y DY+
Sbjct 4242 IKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKTYLDYI 4301
Query 4262 ASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCD 4321
GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+ G C
Sbjct 4302 QQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDVDGICK 4361
Query 4322 LKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
L+GK+VQ+P DP+ + L + VC VCG W+ CSC + + FLN
Sbjct 4362 LRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG--SSVAVQSKDLNFLN 4415
Score = 266 bits (679), Expect = 7e-69, Method: Composition-based stats.
Identities = 148/930 (16%), Positives = 296/930 (32%), Gaps = 148/930 (16%)
Query 141 KSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPLDC 200
+D D + K+ A L R+ G +VD C G DC
Sbjct 185 FKFDDYDFSVEAAYAEVHAEPKGKYSQKAYA-LLRQYRGIKPVLFVDQYGCDYSGKLADC 243
Query 201 IKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKS 259
A S+ + ++ + +AW R + QT I
Sbjct 244 ---LQAYGHYSLQDMRQKQSVWLANCDFDIV------VAWHVVRDSRFVMRLQTIATICG 294
Query 260 AKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQECNNMHLST 319
K + + V ++ K M V +++
Sbjct 295 IKYVAQPTEDVVDGDVVIREPVHLLSADAIVLKLPSLM----KVMTHMDDFSIKSIYNVD 350
Query 320 LMKCNHCDEVSWQTCDFLKATCEHCGTENLVIEGPTTCGYLPTNAVVKMPCPACQDPEIG 379
L C + + C +N G + + + C D
Sbjct 351 LCDCGFVMQYGYV----------DCFNDNCDFYGWVSGNMM--DGFSCPLCCTVYDSSEV 398
Query 380 PEHS---VADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPRASADIGSGHT 436
S + + T +G V G YW PR
Sbjct 399 KAQSSGVIPENPVLFTNSTDTVNPDSFNLYGYSV-TPFGSC---IYWSPRP--------- 445
Query 437 GITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFSASTSAFIDTIKSLDY 496
G+ +++ + ++ + + S +T
Sbjct 446 GLWIPIIKSSVKSYDDL----------------------VYSGVVGCKSIVKETALITHA 483
Query 497 KSFKTIVESCGNYKVTKGKPVKGAW------NIGQQRSVLTPLCGFPSQAAGVIR--SIF 548
+ CGN + V +W N G +L + F + A ++
Sbjct 484 LYLDYVQCKCGNLEQNHILGVNNSWCRQLLLNRGDYNMLLKNIDLFVKRRADFACKFAVC 543
Query 549 ARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYT-------SDLLTNSVIIMAYV 601
+LDG+ +S L+ + ++ S +++ + M +
Sbjct 544 GDGF-------------VPFLLDGLIPRSYYLIQSGIFFTSLMSQFSQEVSDMCLKMCIL 590
Query 602 TGGLVQQTSQWLSNLLGTTVEK--------LRPIFEWIEAKLSAGVEFLKDAWEILKFLI 653
V + ++ + + V + + + W L A W + + L+
Sbjct 591 FMDRVSVATFYIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDASAP--ATGWLLYQ-LL 647
Query 654 TGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAK----LRSLNL---- 705
G F + + + + I D K ++ ++ ++ VT+ K L+++N
Sbjct 648 NGFFVVSQANLNFVA-LIPDYAKILVNKFYTFFKLLLECVTVDVLKDMPVLKTINGLVCI 706
Query 706 -GEVFIAQSKGLYRQCIRGKEQLQLLMPLKA-PKEVTFLEGDSHDTVLTSEEVVLKNGEL 763
G F S GL ++P A +++ F EG +E V++++ +
Sbjct 707 VGNKFYNVSTGLI---------PGFVLPCNAQEQQIYFFEG-------VAESVIVEDDVI 750
Query 764 EALETPVDSFT---NGAIVGTPVCVNGLMLLEIKDKEQYCALSP-GLLATNNVFRLKGGA 819
E +++ + S+ V ++ + + + DK ++ + ++ +R
Sbjct 751 ENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGDKFFPIVMNDKNICLLDHAWRFPCAG 810
Query 820 PIKGVTFGED-TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAE 878
+ V F E V E+ V++ F+LD D +L + CS + VE G V +F VV +
Sbjct 811 --RKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILGKVCSEFEVEKGVTVDDFVAVVCD 868
Query 879 AVVKTLQPVSD---LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDD 935
A+ L + + + L++ + YLFD+AG+E +SRMYC+F D E+
Sbjct 869 AIENALNSCKEHPVVGYQVRAFLNKLNENVVYLFDEAGDEAMASRMYCTFAIEDVEDVIS 928
Query 936 AECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEP-- 993
+E E+ ID E ++D + E V + ++ED + + ++
Sbjct 929 SEAVEDTIDGVVEDTINDDEDVVTGDND----DEDVVTGDNDDEDVVTGDNDDEDVVTGD 984
Query 994 -EPEPTPEEPVNQFTGYLKLTDNVAIKCVD 1022
+ E + D+ + D
Sbjct 985 NDDEDVVTGDNDDEDVVTGDNDDEDVVTGD 1014
Score = 172 bits (436), Expect = 1e-40, Method: Composition-based stats.
Identities = 55/157 (35%), Positives = 79/157 (50%), Gaps = 2/157 (1%)
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
L +T NV DI+ A+ VIVN AN H+ HGGGVA A+ A KE+ +
Sbjct 1308 LCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKETAAMV 1367
Query 1070 KLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDILLAPLL 1127
K G VG + +G L K L++VGP+ + LL AY++ N+ D L+ L+
Sbjct 1368 KSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCCLSTLI 1427
Query 1128 SAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
SAGIF SL + V QV + N+K ++ +
Sbjct 1428 SAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDII 1464
Score = 51.2 bits (121), Expect = 6e-04, Method: Composition-based stats.
Identities = 45/177 (25%), Positives = 71/177 (40%), Gaps = 18/177 (10%)
Query 1601 DDTLRSEAFEYYHTL----DESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSV 1656
DD F+ Y L D ++S + + + +V GL S NC+L SV
Sbjct 1057 DDIESIYDFDTYKALLVFNDVYNDALFVSYGSSVETETYFKVNGLWSPTITHTNCWLRSV 1116
Query 1657 LLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGEL--GDVRETMTHLLQ 1714
LL +Q+L KF A++ + + G +F +L K + G V + L
Sbjct 1117 LLVMQKLPFKFKDLAIENMWLSYKVGYNQSFVDYLLTTIPKAIVLPQGGYVADFAYWFLN 1176
Query 1715 HANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDAT 1771
++ N C CG + L G++AV + G + VS C CG + T
Sbjct 1177 QFDI---NAYANWCCLKCGF-SFDLNGLDAVFFYGDI--------VSHVCKCGHNMT 1221
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 25/157 (16%), Positives = 44/157 (28%), Gaps = 15/157 (10%)
Query 1194 EKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMS 1253
+V D+ + +V +L + + + E +
Sbjct 1311 TPNVCFVKGDIINVARLVKADVIVNPANGH-----MLHGGGVAKAIAVAAGKKFSKETAA 1365
Query 1254 FLEKDAPYMVGDVITSGD------ITCVVIPSKKAGGTTE--MLSRALKKVPVDEYITTY 1305
++ VGD S I +V P + G +L+RA K ++ Y
Sbjct 1366 MVKSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKH--LNNYDCCL 1423
Query 1306 PGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEE 1342
AG A +L N KE+
Sbjct 1424 STLISAGIFSVPADVSLTYLLGVVDKQVILVSNNKED 1460
>sp|P0C6U3|R1A_CVHN1 Replicase polyprotein 1a OS=Human coronavirus
HKU1 (isolate N1) OX=443239 GN=1a PE=1 SV=1
Length=4471
Score = 3475 bits (9010), Expect = 0.0, Method: Composition-based stats.
Identities = 1049/2937 (36%), Positives = 1581/2937 (54%), Gaps = 110/2937 (4%)
Query 1488 RDWSYSGQ----RTELGVEFLKRGDKIVYHTLESPVEFHLDGEV--LSLDKLKSLLSLRE 1541
+DW + V++ + + I + + DG +++++ LL
Sbjct 1593 KDWRLINKFDVINGVKTVKYFECPNSIYICSQGKDFGYVCDGSFYKATVNQVCVLL---- 1648
Query 1542 VKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSD 1601
K I V TVD N + + + +G+ G + DG DVTK+K + K + +
Sbjct 1649 AKKIDVLLTVDGVNFKSISLTVGEVFGKILGNVFCDGIDVTKLKCSDFYADKILYQYENL 1708
Query 1602 DTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
A + D+ L Y + L KW G S + + NNCY++ L LQ
Sbjct 1709 SLADISAVQSSFGFDQQQLLAYYNFL-TVCKWSVVVNGPFFSFEQSHNNCYVNVACLMLQ 1767
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESA 1721
+ +KFN QEA+Y RAG AL+LA + E D + + +L+ A+L A
Sbjct 1768 HINLKFNKWQWQEAWYEFRAGRPHRLVALVLAKGHFKFDEPSDATDFIRVVLKQADLSGA 1827
Query 1722 KRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSF 1781
L ++C CG K + GV+AVM+ GTL+ +L G I C C + + F
Sbjct 1828 ICELELICD-CGIKQESRVGVDAVMHFGTLAKTDLFNGYKIGCNCAG-RIVHCTKLNVPF 1885
Query 1782 VMMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVT 1841
++ S P L + AN + G GHYTH+ D + K + G +T
Sbjct 1886 LICSNTPLSKDLPDDV-VAANMFMG-VGVGHYTHLKCGSPYQHYDACSVKKYTGVSGCLT 1943
Query 1842 DVFY-KETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDL-VPTQPLPN 1899
D Y K + T T +Y LD V P L YY + YYT+ I +
Sbjct 1944 DCLYLKNLTQTFTSMLTNYFLDDVEMVAYNPDLSQYYCDNGKYYTKPIIKAQFKPFAKVD 2003
Query 1900 ASFDNFKLTCSNTKFADDLNQMTGFTKP-ASRELSVTFFPDLNGDVVAIDYRHYSASFKK 1958
+ NFKL + LN GF E VT +P GDVV Y + K
Sbjct 2004 GVYTNFKLVGHD--ICAQLNDKLGFNVDLPFVEYKVTVWPVATGDVVLASDDLYVKRYFK 2061
Query 1959 GAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKP-VDTSNSFEVLAVEDTQGMDNLA 2017
G + KP++W + + + + KP + N + VL+V+ +
Sbjct 2062 GCETFGKPVIWFCHDEASLNSLT---------YFNKPSFKSENRYSVLSVDSV------S 2106
Query 2018 CESQQPTSEEVVENPTIQKEV-IECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAAY 2076
ESQ V+E+ KEV ++ KT ++ +I+ + +KV + L D+ Y
Sbjct 2107 EESQGNVVTSVMESQISTKEVKLKGVRKTVKIEDAIIVNDENSSIKVVKSLSLVDVWDMY 2166
Query 2077 VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKR 2136
+ + NELS + T+ + I + L ++ Q + R
Sbjct 2167 LTGCDYVVWVANELSRLVKSPTVREYIRYGIKPITIPIDLLCLRD-DNQTLLVPKIFKAR 2225
Query 2137 LAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVK 2196
+ F ++ ++F +F L FT T IA ++ L L +
Sbjct 2226 AIE--FYGFLKWLFIYVFSLLHFTNDKT----IFYTTEIASKFTFNLFCLALKNAFQTFR 2279
Query 2197 SPKFSKLFTIAMWLLLLSICLGSLICVTAAFG----------------VLLSNFGAPSYC 2240
F K F + + L + + + F + + FG + C
Sbjct 2280 WSIFIKGFLVVATVFLFWFNFLYINVIFSDFYLPNISVFPIFVGRIVMWIKATFGLVTIC 2339
Query 2241 NGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL--DLTIL 2298
+ +L + T FC GSF C +C SG D LD+Y A++ +Q + L ++++
Sbjct 2340 DFYSKLGVG----FTSHFCNGSFICELCHSGFDMLDTYAAIDFVQYEVDRRVLFDYVSLV 2395
Query 2299 GLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--WLMWFIISIVQMAPVSA 2356
L E V+ Y L+T +FY L +Q+F + F+ + WL+ FI+ + M P
Sbjct 2396 KLIVELVIGYSLYTVWFYPLFCLIGLQLFTTWLPDLFMLETMHWLIRFIVFVANMLPAFV 2455
Query 2357 MVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYAN 2416
++R YI + Y + HI+ GC + C+ CYKRN + RV+C+TIV G+ R + + AN
Sbjct 2456 LLRFYIVVTAMYKVVGFIRHIVYGCNKAGCLFCYKRNCSVRVKCSTIVGGVIRYYDITAN 2515
Query 2417 GGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNG 2476
GG GFC H WNC NC +F G+TFI+ E A +LS + KRP+NPTD S Y+V +
Sbjct 2516 GGTGFCVKHQWNCFNCHSFKPGNTFITVEAAIELSKELKRPVNPTDASHYVVTDIKQVGC 2575
Query 2477 ALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASV 2536
+ L++D+ GQ+ Y+ S FV+++NL + K + V+V + + D + +A V
Sbjct 2576 MMRLFYDRDGQRVYDDVDASLFVDINNLLHSKVKVVPNLYVVVVESDA--DRANFLNAVV 2633
Query 2537 YYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSE 2596
+Y+Q + +PILL+D+ L++ + V+ MFD YVDTF + F V + V AH+
Sbjct 2634 FYAQSLYRPILLVDKKLITTACNGISVTQTMFDVYVDTFMSHFDVDRKSFNNFVNIAHAS 2693
Query 2597 LAKGVALDGVLSTFVSAARQGV-VDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYN 2655
L +GV L+ VL TFV R+ +D+DV+T+ + + + + + LE T ++ NN + TY
Sbjct 2694 LREGVQLEKVLDTFVGCVRKCCSIDSDVETRFITKSMISAVAAGLEFTDENYNNLVPTYL 2753
Query 2656 KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNI 2715
K +N+ DLG I A+H+ VAK+ N+S IW + + L+ L+ +++ A K +
Sbjct 2754 KSDNIVAADLGVLIQNGAKHVQGNVAKAANISCIWFIDAFNQLTADLQHKLKKACVKTGL 2813
Query 2716 PFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSI 2775
+LT V ++TT SLKGG ++S ++ +L+C + + + ++P +++
Sbjct 2814 KLKLTFNKQEASVPILTTPFSLKGGVVLSNLLYILFFVSLICFI---LLWALLPTYSVYK 2870
Query 2776 HDGYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGG--SYKNDKSCPVVAA 2833
D + +K I +GV RDI D CFANK FD W+ G Y N CP+V A
Sbjct 2871 SDIHLPAYASFKVIDNGVVRDISVNDLCFANKFFQFDQWYESTFGSVYYHNSMDCPIVVA 2930
Query 2834 IITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLA 2893
++ +IG + +P VLR LHFL F++ CYTP I Y+DF S CVL+
Sbjct 2931 VMDEDIGSTMFNVPTKVLRH-GFHVLHFLTYAFASDSVQCYTPHIQISYNDFYASGCVLS 2989
Query 2894 AECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGS-IIQFPNTYLEGSVRV 2952
+ CT+FK G P PYCY +++ + Y+ L P TRY L + + I+FP+ EG VR+
Sbjct 2990 SLCTMFKRGDGTPHPYCYSDGVMKNASLYTSLVPHTRYSLANSNGFIRFPDVISEGIVRI 3049
Query 2953 VTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLV 3012
V T YCR G CE +E GIC + + WVLNN++YR++ G FCG D +L F+ L+
Sbjct 3050 VRTRSMTYCRVGACEYAEEGICFNFNSSWVLNNDYYRSMPGTFCGRDLFDLFYQFFSSLI 3109
Query 3013 QPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLV 3072
+P+ ++AS + G I+AI+V YY +K +R FG+Y VV N +++ ++F +L +
Sbjct 3110 RPIDFFSLTASSIFGAILAIVVVLVFYYLIKLKRAFGDYTSVVVINVVVWCINFLMLFVF 3169
Query 3073 PAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHW 3132
Y VY+ FY Y+T YF +++S + HLQW M+ I+PFW YV + H W
Sbjct 3170 QVYPICACVYACFYFYVTLYFPSEISVIMHLQWIVMYGAIMPFWFCVTYVAMVIANHVLW 3229
Query 3133 FFNNYLRKRVMFNGVTFSTFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYK 3192
F+ +++ N + STFEE +L TF++ K+ Y +L++ + YNRYL+LYNKY+
Sbjct 3230 LFSYC--RKIGVNVCSDSTFEETSLTTFMITKDSYCRLKNS--VSDVAYNRYLSLYNKYR 3285
Query 3193 YFSGALDTTSYREAACCHLAKALNDFS-NSGADVLYQPPQTSITSAVLQSGFRKMAFPSG 3251
Y+SG +DT +YREAAC LAKA+ F+ N+G DVLYQPP S++++ LQSG KM P+
Sbjct 3286 YYSGKMDTAAYREAACSQLAKAMETFNHNNGNDVLYQPPTASVSTSFLQSGIVKMVSPTS 3345
Query 3252 KVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAG 3311
K+E C+V VT G+ TLNGLWLDD VYCPRHVIC++ +M P+Y LL R + F + +G
Sbjct 3346 KIEPCIVSVTYGSMTLNGLWLDDKVYCPRHVICSSSNMNEPDYSALLCRVTLGDFTIMSG 3405
Query 3312 NVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMR 3371
+ L V+ + MQ C L L V NP TPKY F ++PG+TF+VLA YNG P G + MR
Sbjct 3406 RMSLTVVSYQMQGCQLVLTVSLQNPYTPKYTFGNVKPGETFTVLAAYNGRPQGAFHVTMR 3465
Query 3372 PNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTA 3431
++TIKGSFL GSCGSVG+ + D V F YMH +EL TG H GTD G FYGP+ D Q
Sbjct 3466 SSYTIKGSFLCGSCGSVGYVLTGDSVKFVYMHQLELSTGCHTGTDFTGNFYGPYRDAQVV 3525
Query 3432 QAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILG 3491
Q D T+NV+AWLYAA++N WF+ + DFN+ AM + + D V L
Sbjct 3526 QLPVKDYVQTVNVIAWLYAAILNNCAWFVQNDVCSTEDFNVWAMANGFSQVKADLV--LD 3583
Query 3492 PLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKK 3551
L++ TG+++ + AA+K L G GR ILGS EDE P DV +Q +GV Q K K+
Sbjct 3584 ALASMTGVSIETLLAAIKRLYM-GFQGRQILGSCTFEDELAPSDVYQQLAGVKLQSKTKR 3642
Query 3552 IVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHA 3611
+K T +W+L++ I+ +W++F ++ + + TL ++ + MLLVKHKH
Sbjct 3643 FIKETIYWILISTFLFSCIISAFVKWTIFMYINTH-MIGVTLCVLCFVSFMMLLVKHKHF 3701
Query 3612 FLCLFLLPSLATVAYFN-MVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLI 3670
+L ++++P L T+ Y N +V + WL +++ + + V I
Sbjct 3702 YLTMYIIPVLCTLFYVNYLVVYKEGFRGFTYVWLSYFVPAVNFTYVYEVFYGCILCVFAI 3761
Query 3671 LMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMF 3730
+T ++ D ++ + ++TL+ Y+G+ L++ + ++ + + Y+ +
Sbjct 3762 FITMHSINHDIFSLMFLVGRIVTLISMWYFGSNLEEDVLLF--ITAFLGTYTWTTILSLA 3819
Query 3731 LARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDY 3790
+A+ IV + F ++ I+L Y F+GY CY+G F LLN FR+ +GVY+Y
Sbjct 3820 IAK-IVANWLSVNIFYFTDVPYIKLILLSYLFIGYILSCYWGFFSLLNSVFRMPMGVYNY 3878
Query 3791 LVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLL 3850
+S QE RYMN+ GL PP++S +A LN+KLLGIGG P I+V+ +QSK++DVKC +VVLL
Sbjct 3879 KISVQELRYMNANGLRPPRNSFEAILLNLKLLGIGGVPVIEVSQIQSKLTDVKCANVVLL 3938
Query 3851 SVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVD------I 3904
+ LQ L V S+SKLW C LHN+IL D + AF+K+ LL VL + AVD I
Sbjct 3939 NCLQHLHVASNSKLWQYCSVLHNEILSTSDLSVAFDKLAQLLIVLFANPAAVDTKCLASI 3998
Query 3905 NRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGD-SEVVLKKLKKSLNV 3963
+ + ++ + + LQA+ SEF ++ S+ Y A++ A +G ++ +K+L+K+ N+
Sbjct 3999 DEVSDDYVQDSTVLQALQSEFVNMASFVEYEVAKKNLADAKNSGSVNQQQIKQLEKACNI 4058
Query 3964 AKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALN 4023
AKS ++RD A+ RKLE+MAD A+T MYK+AR DK++KV SA+QTMLF+M+RKLDN ALN
Sbjct 4059 AKSVYERDKAVARKLERMADLALTNMYKEARINDKKSKVVSALQTMLFSMVRKLDNQALN 4118
Query 4024 NIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADS 4083
+I++NA GCVPL+ IP A L +V+PD + D TYA ++W IQ V DAD
Sbjct 4119 SILDNAVKGCVPLSAIPALAANTLTIVIPDKQVFDKVVDNVYVTYAGSVWHIQTVQDADG 4178
Query 4084 KIVQLSEINMDNSPNLAWPLIVTALRANS--AVKLQNNELSPVALRQMSCAAGTTQTACT 4141
QL++I++D++ WPL++ A R N +QNNEL P L+ +G+
Sbjct 4179 INKQLTDISVDSN----WPLVIIANRYNEVANAVMQNNELMPHKLKIQVVNSGSDMNCNI 4234
Query 4142 DDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPK 4201
YYNN GR V A+LSD LK+ + K DG + EL+PPC+F KG K
Sbjct 4235 PTQ--CYYNNGSSGRIVYAVLSDVDGLKYTKIMKDDGNCVV-LELDPPCKFSIQDVKGLK 4291
Query 4202 VKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYL 4261
+KYLYFIKG N L RG V+G+L++T+RLQAG ATE ANS++LS CAF+VDP K Y DY+
Sbjct 4292 IKYLYFIKGCNTLARGWVVGTLSSTIRLQAGVATEYAANSSILSLCAFSVDPKKTYLDYI 4351
Query 4262 ASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCD 4321
GG PI NCVKMLC H GTG AIT+ PEA ++Q+S+GGAS C+YCR ++HP+ G C
Sbjct 4352 QQGGVPIINCVKMLCDHAGTGMAITIKPEATINQDSYGGASVCIYCRARVEHPDVDGICK 4411
Query 4322 LKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLN 4378
L+GK+VQ+P DP+ + L + VC VCG W+ CSC + + FLN
Sbjct 4412 LRGKFVQVPLG-IKDPILYVLTHDVCQVCGFWRDGSCSCVG--SSVAVQSKDLNFLN 4465
Score = 301 bits (770), Expect = 2e-79, Method: Composition-based stats.
Identities = 160/939 (17%), Positives = 315/939 (34%), Gaps = 166/939 (18%)
Query 141 KSYDLGDELGTDPIEDYEQNWNTKHGSGALRELTRELNGGAVTRYVDNNFCGPDGYPLDC 200
+D D D + K+ A L R+ G +VD C G DC
Sbjct 185 FKFDDYDFSVEDAYAEVHAEPKGKYSQKAYA-LLRQYRGIKPVLFVDQYGCDYSGKLADC 243
Query 201 IKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTERSDKSYEH-QTPFEIKS 259
A S+ + ++ + +AW R + QT I
Sbjct 244 ---LQAYGHYSLQDMRQKQSVWLANCDFDIV------VAWHVVRDSRFVMRLQTIATICG 294
Query 260 AK-----KFDTFKGEC----PKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASPQ 310
K D G+ P + ++ V + P + K T I+S+Y V
Sbjct 295 IKYVAQPTEDVVDGDVVIREPVHLLSADAIVLKL-PSLMKVMTHMDDFSIKSIYNVD-LC 352
Query 311 ECNNMHLSTLMKC--NHCDEVSWQTCDFLKATCE-HCGTENLVIEG-PTTCGYLPTNAVV 366
+C + + C ++CD W + + + C T E + G +P N V+
Sbjct 353 DCGFVMQYGYVDCFNDNCDFYGWVSGNMMDGFSCPLCCTVYDSSEVKAQSSGVIPENPVL 412
Query 367 KMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYWVPR 426
+ H + + +S FG C++ + W+P
Sbjct 413 FT------NSTDTVNHDSFNLYGYSVTP-----------FGSCIY----WSPRPGLWIPI 451
Query 427 ASADI-------GSGHTGITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILAS 479
+ + SG G ET L + G+ N +
Sbjct 452 IKSSVKSYDDLVYSGVVGCKSIVKETALITHALYLDYVQCK---CGNLEQNHIL------ 502
Query 480 FSASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQ 539
++ + ++ + G+Y + NI F +
Sbjct 503 -------------GVNNSWCRQLLLNRGDYNMLLK-------NIDLFVKRRA---DFACK 539
Query 540 AAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYT-------SDLLT 592
A + +LDG+ +S L+ + ++ S ++
Sbjct 540 FA-----VCGDGF-------------VPFLLDGLIPRSYYLIQSGIFFTSLMSQFSQEVS 581
Query 593 NSVIIMAYVTGGLVQQTSQWLSNLLGTTVEK--------LRPIFEWIEAKLSAGVEFLKD 644
+ + M + V + ++ + + V + + + W L A
Sbjct 582 DMCLKMCILFMDRVSVATFYIEHYVNRLVTQFKLLGTTLVNKMVNWFNTMLDASAP--AT 639
Query 645 AWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAK----L 700
W + + L+ G+F + + + I D K ++ ++ ++ VT+ K L
Sbjct 640 GWLLYQ-LLNGLFVVSQANFNFVA-LIPDYAKILVNKFYTFFKLLLECVTVDVLKDMPVL 697
Query 701 RSLNL-----GEVFIAQSKGLYRQCIRGKEQLQLLMPLKA-PKEVTFLEGDSHDTVLTSE 754
+++N G F S GL ++P A +++ F EG +E
Sbjct 698 KTINGLVCIVGNKFYNVSTGLI---------PGFVLPCNAQEQQIYFFEG-------VAE 741
Query 755 EVVLKNGELEALETPVDSFT---NGAIVGTPVCVNGLMLLEIKDKEQYCALSP-GLLATN 810
V++++ +E +++ + S+ V ++ + + + DK ++ + +
Sbjct 742 SVIVEDDVIENVKSSLSSYEYCQPPKSVEKICIIDNMYMGKCGDKFFPIVMNDKNICLLD 801
Query 811 NVFRLKGGAPIKGVTFGED-TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEV 869
+R + V F E V E+ V++ F+LD D +L + CS + VE G V
Sbjct 802 QAWRFPCAG--RKVNFNEKPVVMEIPSLMTVKVMFDLDSTFDDILGKVCSEFEVEKGVTV 859
Query 870 TEFACVVAEAVVKTLQPVSD---LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFY 926
+F VV +A+ L + + + L++ + YLFD+AG+E +SRMYC+F
Sbjct 860 DDFVAVVCDAIENALNSCKEHPVVGYQVRAFLNKLNENVVYLFDEAGDEAMASRMYCTFA 919
Query 927 PPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTT 986
D E+ +E E+ ID E ++D + E V + ++ED +
Sbjct 920 IEDVEDVISSEAVEDTIDGVVEDTINDDEDVVTGDND----DEDVVTGDNDDEDVVTGDN 975
Query 987 EQSEIEP---EPEPTPEEPVNQFTGYLKLTDNVAIKCVD 1022
+ ++ + E + D+ + D
Sbjct 976 DDEDVVTGDNDDEDVVTGDNDDEDVVTGDNDDEDVVTGD 1014
Score = 172 bits (437), Expect = 1e-40, Method: Composition-based stats.
Identities = 55/162 (34%), Positives = 79/162 (49%), Gaps = 2/162 (1%)
Query 1005 QFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKE 1064
L +T NV DI+ A+ VIVN AN H+ HGGGVA A+ A KE
Sbjct 1353 PQLYGLCITPNVCFVKGDIINVARLVKADVIVNPANGHMLHGGGVAKAIAVAAGKKFSKE 1412
Query 1065 SDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLN--AGEDIQLLKAAYENFNSQDIL 1122
+ +K G VG + +G L K L++VGP+ + LL AY++ N+ D
Sbjct 1413 TAAMVKSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKHLNNYDCC 1472
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
L+ L+SAGIF SL + V QV + N+K ++ +
Sbjct 1473 LSTLISAGIFSVPADVSLTYLLGVVDKQVILVSNNKEDFDII 1514
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 25/157 (16%), Positives = 44/157 (28%), Gaps = 15/157 (10%)
Query 1194 EKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMS 1253
+V D+ + +V +L + + + E +
Sbjct 1361 TPNVCFVKGDIINVARLVKADVIVNPANGH-----MLHGGGVAKAIAVAAGKKFSKETAA 1415
Query 1254 FLEKDAPYMVGDVITSGD------ITCVVIPSKKAGGTTE--MLSRALKKVPVDEYITTY 1305
++ VGD S I +V P + G +L+RA K ++ Y
Sbjct 1416 MVKSKGVCQVGDCYVSTGGKLCKTILNIVGPDARQDGRQSYVLLARAYKH--LNNYDCCL 1473
Query 1306 PGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEE 1342
AG A +L N KE+
Sbjct 1474 STLISAGIFSVPADVSLTYLLGVVDKQVILVSNNKED 1510
Score = 49.7 bits (117), Expect = 0.002, Method: Composition-based stats.
Identities = 46/205 (22%), Positives = 76/205 (37%), Gaps = 18/205 (9%)
Query 1573 PTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTL----DESFLGRYMSALN 1628
+ +I N + DD F+ Y L D ++S +
Sbjct 1079 DVVTGDNNDEEIVTGDNDDQIVVTGDDVDDIESIYDFDTYKALLVFNDVYNDALFVSYGS 1138
Query 1629 HTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFC 1688
+ + +V GL S NC+L SVLL +Q+L KF A++ + + G +F
Sbjct 1139 SVETETYFKVNGLWSPTITHTNCWLRSVLLVMQKLPFKFKDLAIENMWLSYKVGYNQSFV 1198
Query 1689 ALILAYSNKTVGEL--GDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVM 1746
+L K + G V + L ++ N C CG + L G++A+
Sbjct 1199 DYLLTTIPKAIVLPQGGFVADFAYWFLNQFDI---NAYANWCCLKCGF-SFDLNGLDALF 1254
Query 1747 YMGTLSYDNLKTGVSIPCVCGRDAT 1771
+ G + VS C CG + T
Sbjct 1255 FYGDI--------VSHVCKCGHNMT 1271
>sp|P0C6U6|R1A_CVHNL Replicase polyprotein 1a OS=Human coronavirus
NL63 OX=277944 GN=1a PE=1 SV=1
Length=4060
Score = 2616 bits (6781), Expect = 0.0, Method: Composition-based stats.
Identities = 760/2299 (33%), Positives = 1182/2299 (51%), Gaps = 119/2299 (5%)
Query 2096 LKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQ 2155
L T+A I + S + P + I+ + AQ+ F + +V +
Sbjct 1858 LSTLAVTAIVVVGGCVTSNV-----PTIVSEKISVMDKLDTGAQKFFQ-FGDFVMNNIVL 1911
Query 2156 LCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVKSPKF---SKLFTIAM-WLL 2211
T+ S S +R T+I K+ +K +AK G+ +S K+ S LF I W +
Sbjct 1912 FLTWLLSMFSLLR----TSIMKHDIKVIAKAPKRTGVILTRSFKYNIRSALFVIKQKWCV 1967
Query 2212 LLSICLGSLICVTAAFGVLLSNFGAPS---YCNGVRELYLNSSNVTTMDFCEGSFPCSIC 2268
++++ L+ V + +P C + Y S+ +C S C +C
Sbjct 1968 IVTLFKFLLLLYAIYALVFMIVQFSPFNSLLCGDIVSGYEKST-FNKDIYCGNSMVCKMC 2026
Query 2269 LSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYML-FTKFFYLLGLSAIMQVF 2327
L + + I D ++ L +L +L F + GL + F
Sbjct 2027 LFSYQEFNDLDHTSLVWKHIR----DPILISLQPFVILVILLIFGNMYLRFGLLYFVAQF 2082
Query 2328 FGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCM 2387
F S F+ WF+ P + ++ I HI+ GC ++ C+
Sbjct 2083 ISTFGS-FLGFHQKQWFL----HFVPFDVLCNEFLATFIVCKIVLFVRHIIVGCNNADCV 2137
Query 2388 MCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVA 2447
C K R RV TI+NGM +SFYV ANGG FC HN+ C+NCD+F G+TFI+ ++A
Sbjct 2138 ACSKSARLKRVPLQTIINGMHKSFYVNANGGTCFCNKHNFFCVNCDSFGPGNTFINGDIA 2197
Query 2448 RDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRAN 2507
R+L K + PT + I+D V NG LY + S + + L+
Sbjct 2198 RELGNVVKTAVQPTAPAYVIIDKVDFVNGFYRLYSGDTFWRYDFDITESKYSCKEVLKNC 2257
Query 2508 NTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKM 2567
N N IV++ S + + K+A VY+SQL+C+PI L++ L+S + S + + +
Sbjct 2258 NV----LENFIVYNN-SGSNITQIKNACVYFSQLLCEPIKLVNSELLSTL--SVDFNGVL 2310
Query 2568 FDAYVDTFSATFSVPMEKLKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKD 2627
AYVD +F ++L A ++ A + G+ V D
Sbjct 2311 HKAYVDVLCNSF---FKELTANMSMAECKATLGLT--------------------VSDDD 2347
Query 2628 VIECLKLSHHSDLEVTGDSCNNFMLTYNKV-ENMTPRDLGACIDCNARHINAQVAKSHNV 2686
+ + +H D+ ++ S NNF ++Y K + ++ D+ C+ ++ +N V ++
Sbjct 2348 FVSAVANAHRYDVLLSDLSFNNFFISYAKPEDKLSVYDIACCMRAGSKVVNHNVLIKESI 2407
Query 2687 SLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTC 2746
++W VKD+ +LS++ +K + K + F LT + + V T I K G
Sbjct 2408 PIVWGVKDFNTLSQEGKKYLVKTTKAKGLTFLLTFNDNQAITQVPATSIVAKQGAGFKRT 2467
Query 2747 FKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYTNEIIGYKAIQDGVTRDIISTDDCFAN 2806
+ + L V + + T++ GY +K I++G + + C N
Sbjct 2468 YNFLWYVCLFVVALFIGVSFIDYTTTVTSFHGY-----DFKYIENGQLKVFEAPLHCVRN 2522
Query 2807 KHAGFDAWFSQRGGSYK-NDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRV 2865
F+ W + G N CP+V + R +VPG+P V + G L F +
Sbjct 2523 VFDNFNQWHEAKFGVVTTNSDKCPIVVGVSERI--NVVPGVPTNVY--LVGKTLVFTLQA 2578
Query 2866 FSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSEL 2925
+CY + C+ + CT + G V YCY+T+L+EGS YS L
Sbjct 2579 AFGNTGVCYDFDGVTTSD-----KCIFNSACTRLEGLGGDNV-YCYNTDLIEGSKPYSTL 2632
Query 2926 RPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLN 2984
+P+ Y + ++FP G +R + T YCR G C S G+C +W +N
Sbjct 2633 QPNAYYKYDAKNYVRFPEILARGFGLRTIRTLATRYCRVGECRDSHKGVCFGFD-KWYVN 2691
Query 2985 NEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKF 3044
+ R G CG ++L+ N+ + + +S ++ + A +T + KF
Sbjct 2692 DG--RVDDGYICGDGLIDLLVNVLSIFSSSFSVVAMSGHMLFNFLFAAFITFLCFLVTKF 2749
Query 3045 RRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDV--SFLAH 3102
+RVFG+ ++ V L++ I +V F +Y++ Y F FT V +++ H
Sbjct 2750 KRVFGDLSYGVFTVVCATLIN-NISYVVTQNLFFMLLYAILY----FVFTRTVRYAWIWH 2804
Query 3103 LQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTF-STFEEAALCTFL 3161
+ + + ++P+W+ + F L+ F + + +F G F TFE AA TF+
Sbjct 2805 IAYIVAYFLLIPWWLLTWFSFAAFLELLPNVFKLKISTQ-LFEGDKFIGTFESAAAGTFV 2863
Query 3162 LNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNS 3221
L+ Y +L + + + Y A YNKYKY+SG+ YR A HLAKA+ D++
Sbjct 2864 LDMRSYERLINT--ISPEKLKNYAASYNKYKYYSGSASEADYRCACYAHLAKAMLDYAKD 2921
Query 3222 GADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRH 3281
D+LY PP S S LQSG +KMA PSG VE C+V+V G+T LNG+WL DTV CPRH
Sbjct 2922 HNDMLYSPPTISYNST-LQSGLKKMAQPSGCVERCVVRVCYGSTVLNGVWLGDTVTCPRH 2980
Query 3282 VICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKY 3341
VI + +L +Y+ H+F V V L V+G +M +LR+KV SN TPK+
Sbjct 2981 VIAPSTTVL-IDYDHAYSTMRLHNFSVSHNGVFLGVVGVTMHGSVLRIKVSQSNVHTPKH 3039
Query 3342 KFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYD-CVSFC 3400
F ++PG +F++LACY G SGV+ +R N TIKGSF+NG+CGS G+N+ D V FC
Sbjct 3040 VFKTLKPGDSFNILACYEGIASGVFGVNLRTNFTIKGSFINGACGSPGYNVRNDGTVEFC 3099
Query 3401 YMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFL 3460
Y+H +EL +G H G+D G YG F D+ + Q + ++ NV+A+LYAA++NG RW+L
Sbjct 3100 YLHQIELGSGAHVGSDFTGSVYGNFDDQPSLQVESANLMLSDNVVAFLYAALLNGCRWWL 3159
Query 3461 NRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRT 3520
++ FN AM Y ++ V+ L+A+TG++V + A+++ L G G+
Sbjct 3160 CSTRVNVDGFNEWAMANGYTSVSS--VECYSILAAKTGVSVEQLLASIQHL-HEGFGGKN 3216
Query 3521 ILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLF 3580
ILG + L DEFT +VV+Q GV Q K++ G L + ++ ++
Sbjct 3217 ILGYSSLCDEFTLAEVVKQMYGVNLQSG--KVIFGLKTMFLFSVFFTMFWAELFI-YTNT 3273
Query 3581 FFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRI 3640
++ P ++ ++ + +KHK FL +FLLP++ A +N V ++++
Sbjct 3274 IWINPVILTPIFCLLLFLSLVLTMFLKHKFLFLQVFLLPTVIATALYNCVLD--YYIVKF 3331
Query 3641 MTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYY 3700
+ + S+ ++ V L ++ L T R + + ++I + Y +Y
Sbjct 3332 LADHFNYNVSVLQMDVQGLVNVLVCLFVVFLHTWRFSKERFTHWFTYVCSLIAVAYTYFY 3391
Query 3701 GNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVY 3760
+S+ + + S+ + + L+R IVF E +F ++ ++VY
Sbjct 3392 SGDF---LSLLVMFLCAISSDWYIGAIVFRLSRLIVFFSPE---SVFSVFGDVKLTLVVY 3445
Query 3761 CFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIK 3820
GY C Y+G+ NR+F+ T+GVYD+ VS EF+YM + GL P DA L+ K
Sbjct 3446 LICGYLVCTYWGILYWFNRFFKCTMGVYDFKVSAAEFKYMVANGLHAPHGPFDALWLSFK 3505
Query 3821 LLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKD 3880
LLGIGG CIK++TVQSK++D+KCT+VVLL L + + ++S WA CV LHN I L D
Sbjct 3506 LLGIGGDRCIKISTVQSKLTDLKCTNVVLLGCLSSMNIAANSSEWAYCVDLHNKINLCDD 3565
Query 3881 TTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEA 3940
+A +++LL+ LS ++ L + DN +TLQ++AS F S+PSY AY A++A
Sbjct 3566 PEKAQSMLLALLAFFLSKHSDFGLDGLIDSYFDNSSTLQSVASSFVSMPSYIAYENARQA 3625
Query 3941 YEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRA 4000
YE A+ANG S ++K+LK+++N+AKSEFD + ++Q+K+ +MA+QA TQMYK+ARS ++++
Sbjct 3626 YEDAIANGSSSQLIKQLKRAMNIAKSEFDHEISVQKKINRMAEQAATQMYKEARSVNRKS 3685
Query 4001 KVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNT 4060
KV SAM ++LF MLR+LD ++ ++N ARDG VPL++IP T+A+KL +V PD +Y
Sbjct 3686 KVISAMHSLLFGMLRRLDMSSVETVLNLARDGVVPLSVIPATSASKLTIVSPDLESYSKI 3745
Query 4061 CDGNTFTYASALWEIQQVVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNE 4120
+ YA +W + V D D + V + EI +N L WPLI+ R VKLQNNE
Sbjct 3746 VCDGSVHYAGVVWTLNDVKDNDGRPVHVKEITKENVETLTWPLILNCER---VVKLQNNE 3802
Query 4121 LSPVALRQMSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTG 4180
+ P L+Q A D NAL YN G F+ A +S+ DLK+ ++ G
Sbjct 3803 IMPGKLKQKPMKAEGDGGVLGDGNAL--YNTEGGKTFMYAYISNKADLKFVKWEYEGGCN 3860
Query 4181 TIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPAN 4240
TI EL+ PCRF+ +TP GP+VKYLYF+K LN L RG VLG + AT+RLQAG TE+ N
Sbjct 3861 TI--ELDSPCRFMVETPNGPQVKYLYFVKNLNTLRRGAVLGFIGATIRLQAGKQTELAVN 3918
Query 4241 STVLSFCAFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGG 4300
S +L+ CAF+VDPA Y + + G +P++NC+KML G GQAIT + +AN +Q+S+GG
Sbjct 3919 SGLLTACAFSVDPATTYLEAVKHGAKPVSNCIKMLSNGAGNGQAITTSVDANTNQDSYGG 3978
Query 4301 ASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSC 4360
AS CLYCR H+ HP+ G+C KGK VQ+P C DP+ F L N VC VCG W G+GC+C
Sbjct 3979 ASICLYCRAHVPHPSMDGYCKFKGKCVQVPIGCL-DPIRFCLENNVCNVCGCWLGHGCAC 4037
Query 4361 DQLREPLMQSADASTFLNR 4379
D+ +QS D S +LN
Sbjct 4038 DR---TTIQSVDIS-YLNE 4052
Score = 233 bits (595), Expect = 3e-59, Method: Composition-based stats.
Identities = 116/653 (18%), Positives = 220/653 (34%), Gaps = 95/653 (15%)
Query 1227 NKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSG----DITCVVIPSKKA 1282
LL + + ++ L+ ++ + P VG + ++ VV P
Sbjct 1291 ENLLHGGGVARAIDILTEGQLQSLSKDYISSNGPLKVGAGVMLECEKFNVFNVVGPRTG- 1349
Query 1283 GGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEE 1342
+L A + + I P C + + +++ L S N +
Sbjct 1350 KHEHSLLVEAYNSILFENGIPLMPLLSCGIFGVR--------IENSLKALFSCDINKPLQ 1401
Query 1343 ILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYT 1402
+ S + +L + P+ DV + K ++ D GV
Sbjct 1402 VFVYSSNEEQAVLKFLDGLDLT-PVIDDVDVV------KPFRVEGNFSFFDCGV------ 1448
Query 1403 SKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRS-----LKAPAVVSVSSPD 1457
N+L+ + + + L++ + + + L+ A+ +++
Sbjct 1449 ------------NALDGDIYLL---FTNSILMLDKQGQLLDTKLNGILQQAALDYLATVK 1493
Query 1458 AVTTYNGYLTSSSKTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTL-- 1515
V N K E + + S D S+ V L R V +
Sbjct 1494 TVPAGNL-----VKLFVESCTIYMCVVPSINDLSFDKNLGRC-VRKLNRLKTCVIANVPA 1547
Query 1516 -----------ESPVEFHLDGEVLSLDKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMS 1564
V+F ++ V+ ++ + + + T D N+ +V+ S
Sbjct 1548 IDVLKKLLSSLTLTVKFVVESNVMDVNDC------FKNDNVVLKITEDGINVKDVVVESS 1601
Query 1565 MTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYM 1624
+ G+Q G DG D + EG + + DT+ S A E F +
Sbjct 1602 KSLGKQLGVVS-DGVD--------SFEG---VLPINTDTVLSVAPEVDWVAFYGFEKAAL 1649
Query 1625 SALNHTKKWKFP--QVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAG 1682
A K + +P VGG + DNNC++++ + LQ L+ F + L + + G
Sbjct 1650 FASLDVKPYGYPNDFVGGFRVLGTTDNNCWVNATCIILQYLKPTFKSKGLNVLWNKFVTG 1709
Query 1683 DAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGV 1742
D F + I + + G+ GD E ++ L ++ L S V C +T+ V
Sbjct 1710 DVGPFVSFIYFITMSSKGQKGDAEEALSKLSEY--LISDSIVTLEQYSTCDICKSTVVEV 1767
Query 1743 EAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLCAN 1802
++ + ++ LK G + R + V+ + V+++ Q L
Sbjct 1768 KSAIVCASV----LKDGCDVGFCPHRHKLRSRVKFVNGRVVITNVGEPIISQPSKLLNGI 1823
Query 1803 EYT---GNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTT 1852
YT G++ GHY A DGA L VT + T+
Sbjct 1824 AYTTFSGSFDNGHYVVYDAANN-AVYDGARLFSSDLSTLAVTAIVVVGGCVTS 1875
Score = 164 bits (416), Expect = 2e-38, Method: Composition-based stats.
Identities = 91/408 (22%), Positives = 147/408 (36%), Gaps = 40/408 (10%)
Query 901 WSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGL 960
+ + S + D D + I + YQ
Sbjct 1157 FQKGECCICHKMQTYKLVSMKGTGVFVQDPAPIDIDAFPVKPICSSVYLGVKGSGHYQTN 1216
Query 961 PLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKC 1020
F + + V + ++ +T +++ V F + NV
Sbjct 1217 LYSFNKAIDGFGVFDI--KNSSVNTVCFVDVDFHSVEIEAGEVKPFA----VYKNVKFYL 1270
Query 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
DI + +VNAAN +L HGGGVA A++ T G +Q S DYI NGPL VG
Sbjct 1271 GDISHLVNCVSFDFVVNAANENLLHGGGVARAIDILTEGQLQSLSKDYISSNGPLKVGAG 1330
Query 1081 CLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSL 1140
+L +VVGP E L++A I L PLLS GIFG + SL
Sbjct 1331 VMLECEKF--NVFNVVGPRTGKHEHSLLVEAYNSILFENGIPLMPLLSCGIFGVRIENSL 1388
Query 1141 Q---VCVQTVRTQVYIAVNDKALYEQVVMDYLD--NLKPRVEAPKQEEPPNTEDSKTEEK 1195
+ C QV++ +++ EQ V+ +LD +L P ++ +P E + +
Sbjct 1389 KALFSCDINKPLQVFVYSSNE---EQAVLKFLDGLDLTPVIDDVDVVKPFRVEGNFSFF- 1444
Query 1196 SVVQKPVDVKPKIKACIDEVTTTLEETKFL--TNKLLLFADINGKLYHDSQNMLRGEDMS 1253
D L+ +L TN +L+ L +L+ +
Sbjct 1445 -----------------DCGVNALDGDIYLLFTNSILMLDKQGQLLDTKLNGILQQAALD 1487
Query 1254 FLEKDAPYMVGDV----ITSGDITCVVIPSKKAGGTTEMLSRALKKVP 1297
+L G++ + S I V+PS + L R ++K+
Sbjct 1488 YLATVKTVPAGNLVKLFVESCTIYMCVVPSINDLSFDKNLGRCVRKLN 1535
Score = 78.9 bits (193), Expect = 2e-12, Method: Composition-based stats.
Identities = 51/263 (19%), Positives = 93/263 (35%), Gaps = 30/263 (11%)
Query 1617 ESFLGRYMSALNHTKKWKFPQVG--GLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQE 1674
E L+ + + F G+ + +DNNC++S+ L+ LQ ++ ++ +Q
Sbjct 1026 EQPFEEVEHVLSIKQPFSFSFRDELGVRVLDQSDNNCWISTTLVQLQLTKLLDDSIEMQL 1085
Query 1675 AYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQ 1734
+ G + S+ G LGD + ++ LL+ S + C CG+
Sbjct 1086 ----FKVGKVDSIVQKCYELSHLISGSLGDSGKLLSELLKEKYTCSIT--FEMSCD-CGK 1138
Query 1735 KTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAP-PAEYKL 1793
K G ++ + G C+C + T LV + + V + P P +
Sbjct 1139 KFDDQVG---CLFWIMPYTKLFQKG--ECCICHKMQTYKLVSMKGTGVFVQDPAPIDIDA 1193
Query 1794 QQGTFLCANEYTGNYQCGHY---THITAK--ETLYRIDGAHLTKMSEYKGPVTDVFY--- 1845
+C++ Y G GHY + K + D + S DV +
Sbjct 1194 FPVKPICSSVYLGVKGSGHYQTNLYSFNKAIDGFGVFD---IKNSSVNTVCFVDVDFHSV 1250
Query 1846 ----KETSYTTTIKPVSYKLDGV 1864
E K V + L +
Sbjct 1251 EIEAGEVKPFAVYKNVKFYLGDI 1273
Score = 57.0 bits (136), Expect = 8e-06, Method: Composition-based stats.
Identities = 42/179 (23%), Positives = 56/179 (31%), Gaps = 30/179 (17%)
Query 179 GGAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEI 238
G +VD CG DG P+ + E DY + +++
Sbjct 108 GAGSVVFVDKYMCGFDGKPVLP------------KNMWEFRDYFNNNTDSIVIGGVTYQL 155
Query 239 AWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMG 298
AW R D SYE Q I+S T K+ +P K G
Sbjct 156 AWDVIRKDLSYEQQNVLAIESIHYLGTT-----GHTLKSGCKLTNAKPPKYSSKVV-LSG 209
Query 299 RIRSVY-PVASPQECNNMHL----------STLMKCNHCDEVSWQTCDFLKATCEHCGT 346
+VY SP N M L + +KCN C SW + CGT
Sbjct 210 EWNAVYRAFGSPFITNGMSLLDIIVKPVFFNAFVKCN-CGSESWSVGAWDGYLSSCCGT 267
>sp|P0C6U2|R1A_CVH22 Replicase polyprotein 1a OS=Human coronavirus
229E OX=11137 GN=1a PE=1 SV=1
Length=4085
Score = 2608 bits (6760), Expect = 0.0, Method: Composition-based stats.
Identities = 757/2325 (33%), Positives = 1188/2325 (51%), Gaps = 128/2325 (6%)
Query 2077 VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCAKR 2136
V+ T+ + S+ G + + H ++ ++ + YV P N
Sbjct 1859 VDKGHYTVYDTAKKSMYDGDRFV-KHDLSLLSVTSVVMVGGYVAPVNTVKPKPVINQLDE 1917
Query 2137 LAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINYVK 2196
AQ+ F ++ ++ T+ S + + T + VK +AK G+ +
Sbjct 1918 KAQKFF-DFGDFLIHNFVIFFTWLLSMFTLCK----TAVTTGDVKIMAKAPQRTGVVLKR 1972
Query 2197 SPKFSKLFTIAM-----WLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSS 2251
S K++ + A+ WLL L LI + +L FG ++C+ Y S
Sbjct 1973 SLKYNLKASAAVLKSKWWLLAKFTKLLLLIYTLYSVVLLCVRFGPFNFCSETVNGYAKS- 2031
Query 2252 NVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISS--------YKLDLTILGLAAE 2303
N D+C+GS C +CL G L + L+ + I+ + + + +L
Sbjct 2032 NFVKDDYCDGSLGCKMCLFGYQELSQFSHLDVVWKHITDPLFSNMQPFIVMVLLLIFGDN 2091
Query 2304 WVLAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIF 2363
++ ++L+ ++ + + + VF GY ++ WF+ P + +
Sbjct 2092 YLRCFLLY----FVAQMISTVGVFLGYKETN--------WFL----HFIPFDVICDELLV 2135
Query 2364 FASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCK 2423
+ H++ GC + C+ C K R R TIVNG++RSFYV ANGG FCK
Sbjct 2136 TVIVIKVISFVRHVLFGCENPDCIACSKSARLKRFPVNTIVNGVQRSFYVNANGGSKFCK 2195
Query 2424 THNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFD 2483
H + C++CD++ GSTFI+ EV+R+L K + PT + ++D V +NG LY
Sbjct 2196 KHRFFCVDCDSYGYGSTFITPEVSRELGNITKTNVQPTGPAYVMIDKVEFENGFYRLYSC 2255
Query 2484 KAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMC 2543
+ + S + + + N + IVF+ + + K+ASVY+SQL+C
Sbjct 2256 ETFWRYNFDITESKYSCKEVFKNCNV----LDDFIVFNNNGT-NVTQVKNASVYFSQLLC 2310
Query 2544 QPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVAL 2603
+PI L+D L+S + S + + + AY+D +F L A ++ A + A G+++
Sbjct 2311 RPIKLVDSELLSTL--SVDFNGVLHKAYIDVLRNSFGKD---LNANMSLAECKRALGLSI 2365
Query 2604 DGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVE-NMTP 2662
+ + +H D+ ++ S NNF+ +Y K E ++
Sbjct 2366 SD--------------------HEFTSAISNAHRCDVLLSDLSFNNFVSSYAKPEEKLSA 2405
Query 2663 RDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTCA 2722
DL C+ A+ +NA V ++W+ KD+ SLS + RK I +K + F LT
Sbjct 2406 YDLACCMRAGAKVVNANVLTKDQTPIVWHAKDFNSLSAEGRKYIVKTSKAKGLTFLLTIN 2465
Query 2723 TTRQVVNVITTKISLKGGKI--VSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHDGYT 2780
+ V + T I K G + L L L+C++ +C+ MP I +
Sbjct 2466 ENQAVTQIPATSIVAKQGAGDAGHSLTWLWLLCGLVCLIQFYLCFF-MPYFMYDIVSSF- 2523
Query 2781 NEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGS-YKNDKSCPVVAAIITREI 2839
E +K I++G ++ + C N F+ W + G N +SCP+V + EI
Sbjct 2524 -EGYDFKYIENGQLKNFEAPLKCVRNVFENFEDWHYAKFGFTPLNKQSCPIVVGV--SEI 2580
Query 2840 GFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIF 2899
V G+P V + G L F + +CY + C+ + CT
Sbjct 2581 VNTVAGIPSNVY--LVGKTLIFTLQAAFGNAGVCYD-----IFGVTTPEKCIFTSACTRL 2633
Query 2900 KDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEG-SVRVVTTFDA 2958
+ G V YCY+T L+EGS+ YS ++ + Y +G+ I+ P +G R V T
Sbjct 2634 EGLGGNNV-YCYNTALMEGSLPYSSIQANAYYKYDNGNFIKLPEVIAQGFGFRTVRTIAT 2692
Query 2959 EYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGAL 3018
+YCR G C S G+C +W +N+ R +G CG NL+ NI +
Sbjct 2693 KYCRVGECVESNAGVCFGFD-KWFVNDG--RVANGYVCGTGLWNLVFNILSMFSSSFSVA 2749
Query 3019 DVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFL 3078
+S ++ + + KFRR+FG+ + ++ ++ + +V
Sbjct 2750 AMSGQILLNCALGAFAIFCCFLVTKFRRMFGDLSVG-VCTVVVAVLLNNVSYIVTQNLVT 2808
Query 3079 PGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYL 3138
Y++ Y + T +++ + + P+W+ A Y + +
Sbjct 2809 MIAYAILYFFATRSL--RYAWIWCAAYLIAYISFAPWWLCAWYFLAMLTGLLPSLLKLKV 2866
Query 3139 RKRVMFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGA 3197
+F G F TFE AA TF+++ Y KL + + + Y A YN+YKY+SG
Sbjct 2867 STN-LFEGDKFVGTFESAAAGTFVIDMRSYEKLANS--ISPEKLKSYAASYNRYKYYSGN 2923
Query 3198 LDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCM 3257
+ YR A +LAKA+ DFS D+LY PP S S LQ+G RKMA PSG VE C+
Sbjct 2924 ANEADYRCACYAYLAKAMLDFSRDHNDILYTPPTVSYGST-LQAGLRKMAQPSGFVEKCV 2982
Query 3258 VQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNVQLRV 3317
V+V G T LNGLWL D VYCPRHVI + +Y+ H+F + +G L V
Sbjct 2983 VRVCYGNTVLNGLWLGDIVYCPRHVIASNTT-SAIDYDHEYSIMRLHNFSIISGTAFLGV 3041
Query 3318 IGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIK 3377
+G +M L++KV +N TP++ F ++ G+ F++LACY+G GV+ MR N TI+
Sbjct 3042 VGATMHGVTLKIKVSQTNMHTPRHSFRTLKSGEGFNILACYDGCAQGVFGVNMRTNWTIR 3101
Query 3378 GSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTD 3437
GSF+NG+CGS G+N+ V F YMH +EL +G H G+ +G YG F D+ Q +
Sbjct 3102 GSFINGACGSPGYNLKNGEVEFVYMHQIELGSGSHVGSSFDGVMYGGFEDQPNLQVESAN 3161
Query 3438 TTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQT 3497
+T+NV+A+LYAA++NG W+L + +N A + + + D L+A+T
Sbjct 3162 QMLTVNVVAFLYAAILNGCTWWLKGEKLFVEHYNEWAQANGFTAMNGE--DAFSILAAKT 3219
Query 3498 GIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ-GKFKKIVKGT 3556
G+ V + A++ +L NG G+ ILG + L DEF+ +VV+Q GV Q GK + K
Sbjct 3220 GVCVERLLHAIQ-VLNNGFGGKQILGYSSLNDEFSINEVVKQMFGVNLQSGKTTSMFKSI 3278
Query 3557 HHWM-LLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCL 3615
+ + L + +T W V PF + ++A++ C +VKHK FL +
Sbjct 3279 SLFAGFFVMFWAELFVYTTTIW-----VNPGFLTPFMILLVALSLCLTFVVKHKVLFLQV 3333
Query 3616 FLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTAR 3675
FLLPS+ A N + V +++ + S+ ++ V L + +L T R
Sbjct 3334 FLLPSIIVAAIQNCAWD--YHVTKVLAEKFDYNVSVMQMDIQGFVNIFICLFVALLHTWR 3391
Query 3676 TVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARA- 3734
+ L ++I ++Y Y +S+ +++ SN + I + R
Sbjct 3392 FAKERCTHWCTYLFSLIAVLYTALYSY---DYVSLLVMLLCAISNEWYIGAIIFRICRFG 3448
Query 3735 IVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVST 3794
+ F+ VEY + ++ ++L Y LG+ C Y+GL +NR+ + TLGVYD+ VS
Sbjct 3449 VAFLPVEYVSY----FDGVKTVLLFYMLLGFVSCMYYGLLYWINRFCKCTLGVYDFCVSP 3504
Query 3795 QEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLLSVLQ 3854
EF+YM + GL P DA L+ KL+GIGG IKV+TVQSK++D+KCT+VVL+ +L
Sbjct 3505 AEFKYMVANGLNAPNGPFDALFLSFKLMGIGGPRTIKVSTVQSKLTDLKCTNVVLMGILS 3564
Query 3855 QLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEEMLDN 3914
+ + S+SK WA CV++HN I L D A E +++LL+ LS + L + +N
Sbjct 3565 NMNIASNSKEWAYCVEMHNKINLCDDPETAQELLLALLAFFLSKHSDFGLGDLVDSYFEN 3624
Query 3915 RATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAM 3974
+ LQ++AS F +PS+ AY TA++ YE AVANG S ++K+LKK++NVAK+EFDR++++
Sbjct 3625 DSILQSVASSFVGMPSFVAYETARQEYENAVANGSSPQIIKQLKKAMNVAKAEFDRESSV 3684
Query 3975 QRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCV 4034
Q+K+ +MA+QA MYK+AR+ ++++KV SAM ++LF MLR+LD +++ I+N AR+G V
Sbjct 3685 QKKINRMAEQAAAAMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILNMARNGVV 3744
Query 4035 PLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLSEINMD 4094
PL++IP T+AA+L+VVVPD+ ++ YA +W +Q+V D D K V L ++ +
Sbjct 3745 PLSVIPATSAARLVVVVPDHDSFVKMMVDGFVHYAGVVWTLQEVKDNDGKNVHLKDVTKE 3804
Query 4095 NSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNNSKG 4154
N L WPLI+T R VKLQNNE+ P ++ + ++ NAL YNN G
Sbjct 3805 NQEILVWPLILTCER---VVKLQNNEIMPGKMKVKATKGEGDGGITSEGNAL--YNNEGG 3859
Query 4155 GRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNL 4214
F+ A ++ +K+ ++ G T+ ELEPPCRFV DTP GP++KYLYF+K LNNL
Sbjct 3860 RAFMYAYVTTKPGMKYVKWEHDSGVVTV--ELEPPCRFVIDTPTGPQIKYLYFVKNLNNL 3917
Query 4215 NRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPITNCVKM 4274
RG VLG + ATVRLQAG TE +NS +L+ C+FAVDPA AY D + G +P+ NCVKM
Sbjct 3918 RRGAVLGYIGATVRLQAGKQTEFVSNSHLLTHCSFAVDPAAAYLDAVKQGAKPVGNCVKM 3977
Query 4275 LCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCA 4334
L +G+GQAIT T ++N Q+++GGAS C+YCR H+ HP GFC KGK+VQ+P
Sbjct 3978 LTNGSGSGQAITCTIDSNTTQDTYGGASVCIYCRAHVAHPTMDGFCQYKGKWVQVPIG-T 4036
Query 4335 NDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
NDP+ F L NTVC VCG W +GC+CD+ +QS D S +LN
Sbjct 4037 NDPIRFCLENTVCKVCGCWLNHGCTCDR---TAIQSFDNS-YLNE 4077
Score = 276 bits (706), Expect = 5e-72, Method: Composition-based stats.
Identities = 133/733 (18%), Positives = 248/733 (34%), Gaps = 78/733 (11%)
Query 1155 VNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTED--SKTEEKSVVQKPVDVKPKIKACI 1212
A Y V + +K V+ +EE E + +V DV +
Sbjct 1237 CIKDADYNAKVEISVTPIKNTVDTTPKEEFVVKEKLNAFLVHDNVAFYQGDVDTVVNGVD 1296
Query 1213 DEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVIT---- 1268
+ L + L ++ L+ + VG +
Sbjct 1297 FDFIVNAAN-----ENLAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTGVMVECD 1351
Query 1269 SGDITCVVIPSKKAGGTTEMLSRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSA 1328
S I VV P +K ++L +A + +E T G + +T+L+
Sbjct 1352 SLRIFNVVGP-RKGKHERDLLIKAYNTIN-NEQGTPLTPILSCGIFGIKLETSLEVLLDV 1409
Query 1329 FYVLPSEAPNAKEEILGTVSWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQ 1388
+ + + V + ++ + + + ++ I+ + +
Sbjct 1410 CNTKEVKVFVYTDTEVCKVKDFVSGLVNVQKVEQPKI-----EPKPVSVIK-----VAPK 1459
Query 1389 EGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGYVTHGFNLEEAARCMRSLKAP 1448
VD +F ++ + +P+V + L++ + +
Sbjct 1460 PYRVDGKFSYF-------TEDLLCVADD--KPIVL----FTDSMLTLDDRGLALDN-ALS 1505
Query 1449 AVVSVSSPDAVTTYNGYLTSS--SKTSEEHFVETVSLAGSYRDWSYSGQRTELGVEFLKR 1506
V+S + D V N + S K V + + S +D K
Sbjct 1506 GVLSAAIKDCVDI-NKAIPSGNLIKFDIGSVVVYMCVVPSEKDKHLDNNVQRCT---RKL 1561
Query 1507 GDKIVYHTLESPVEFHLDGEVLSLDKLKSL---LSLREVKTIKVFTTVDNTNLHTQLVDM 1563
+ P ++ L + SL S L E K I + T D N+H V
Sbjct 1562 NRLMCDIVCTIPADYILPLVLSSLTCNVSFVGELKAAEAKVITIKVTEDGVNVHDVTVTT 1621
Query 1564 SMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDDTLRSEAFE---YYHTLDESFL 1620
++ QQ G D++ P + + D + F+ + T+D S
Sbjct 1622 DKSFEQQVGVIADKDKDLSGAVPSDLNTSELLTKAIDVDWVEFYGFKDAVTFATVDHSAF 1681
Query 1621 GRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRAR 1680
++ V G+ +K +DNNC++++V +ALQ + F + L A+ +
Sbjct 1682 A-----------YESAVVNGIRVLKTSDNNCWVNAVCIALQYSKPHFISQGLDAAWNKFV 1730
Query 1681 AGDAANFCALILAYSNKTVGELGDVRETMTHLLQH-ANLESAKRVLNVVCKHCGQK-TTT 1738
GD F A + + G+ GD +T+T L ++ AN + C C K +
Sbjct 1731 LGDVEIFVAFVYYVARLMKGDKGDAEDTLTKLSKYLANEAQVQLEHYSSCVECDAKFKNS 1790
Query 1739 LTGVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSA----PPAEYKLQ 1794
+ + + + ++ D ++ G CV G + +++S P A+ +L
Sbjct 1791 VASINSAIVCASVKRDGVQVGY---CVHGIKYYSRVRSVRGRAIIVSVEQLEPCAQSRLL 1847
Query 1795 QGTFLCANEYTGNYQCGHYT-HITAKETLYRIDGAHLTKMSEYKGPVTDVF----YKETS 1849
G A ++G GHYT + TAK+++ DG K VT V Y
Sbjct 1848 SGVAYTA--FSGPVDKGHYTVYDTAKKSM--YDGDRFVKHDLSLLSVTSVVMVGGYVAPV 1903
Query 1850 YTTTIKPVSYKLD 1862
T KPV +LD
Sbjct 1904 NTVKPKPVINQLD 1916
Score = 177 bits (449), Expect = 3e-42, Method: Composition-based stats.
Identities = 114/580 (20%), Positives = 211/580 (36%), Gaps = 58/580 (10%)
Query 985 TTEQSEIEPEPEPTPEEP--VNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIH 1042
+ I+ + TP+E V + + DNVA D+ + IVNAAN +
Sbjct 1248 EISVTPIKNTVDTTPKEEFVVKEKLNAFLVHDNVAFYQGDVDTVVNGVDFDFIVNAANEN 1307
Query 1043 LKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNA 1102
L HGGG+A AL+ T G +Q+ S ++I L G + VG ++ +L + +VVGP
Sbjct 1308 LAHGGGLAKALDVYTKGKLQRLSKEHIGLAGKVKVGTGVMVECDSL--RIFNVVGPRKGK 1365
Query 1103 GEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT---QVYIAVNDKA 1159
E L+KA N Q L P+LS GIFG K SL+V + T +V++ + +
Sbjct 1366 HERDLLIKAYNTINNEQGTPLTPILSCGIFGIKLETSLEVLLDVCNTKEVKVFVYTDTEV 1425
Query 1160 LYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTL 1219
+ + L N++ +VE PK E P V KP V K + E +
Sbjct 1426 CKVKDFVSGLVNVQ-KVEQPKIEPKP------VSVIKVAPKPYRVDGKF-SYFTEDLLCV 1477
Query 1220 EETK---FLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSG----DI 1272
+ K T+ +L D L + +L ++ + G++I +
Sbjct 1478 ADDKPIVLFTDSMLTLDDRGLALDNALSGVLSAAIKDCVDINKAIPSGNLIKFDIGSVVV 1537
Query 1273 TCVVIPSKKAGGTTEMLSRALKKVPV------------DEYITTYPGQGCAGYTLEEAKT 1320
V+PS+K + R +K+ C + E K
Sbjct 1538 YMCVVPSEKDKHLDNNVQRCTRKLNRLMCDIVCTIPADYILPLVLSSLTCNVSFVGELKA 1597
Query 1321 ALKKCKSAFYVLPSEAPNAKEEILGTVSWNLREMLA-HAEETRKLMPICMDVRAIM-ATI 1378
A K + + ++A ++ +P ++ ++ I
Sbjct 1598 AEAKVITIKVTEDGVNVHDVTVTTDKSFEQQVGVIADKDKDLSGAVPSDLNTSELLTKAI 1657
Query 1379 QRKYKGI-----KIQEGIVDYGVRFFFYTSKEPVASIITKLNSLNEPLVTMPIGY----- 1428
+ + VD+ + + + T N+ V + + Y
Sbjct 1658 DVDWVEFYGFKDAVTFATVDHSAFAYESAVVNGIRVLKTSDNNCWVNAVCIALQYSKPHF 1717
Query 1429 VTHGFNLEEAARCMRSLK--APAVVSVS---------SPDAVTTYNGYLTSSSKTSEEHF 1477
++ G + + ++ V V+ + D +T + YL + ++ EH+
Sbjct 1718 ISQGLDAAWNKFVLGDVEIFVAFVYYVARLMKGDKGDAEDTLTKLSKYLANEAQVQLEHY 1777
Query 1478 VETVSLAGSYRDWSYSGQRTELGVEFLKRGDKIVYHTLES 1517
V +++ S + + + +KR V + +
Sbjct 1778 SSCVECDAKFKN-SVASINSAIVCASVKRDGVQVGYCVHG 1816
Score = 98.2 bits (243), Expect = 3e-18, Method: Composition-based stats.
Identities = 51/269 (19%), Positives = 95/269 (35%), Gaps = 24/269 (9%)
Query 1634 KFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILA 1693
F ++ GL +K DNNC+++SV+L +Q + A+Q + G A
Sbjct 1037 PFEELNGLKILKQLDNNCWVNSVMLQIQLTGILDGDYAMQF----FKMGRVAKMIERCYT 1092
Query 1694 YSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSY 1753
G +GDV M LL+ +L + V++ C + V
Sbjct 1093 AEQCIRGAMGDVGLCMYRLLK--DLHTGFMVMDYKCSCTSGRLEESGAVLFCTPTKK--- 1147
Query 1754 DNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTF--LCANEYTGNYQCG 1811
C + Q + + + + P +C++ + G CG
Sbjct 1148 ---AFPYGTCLNCNAPRMCTIRQLQGTIIFVQQKPEPVNPVSFVVKPVCSSIFRGAVSCG 1204
Query 1812 HYTHITAKETLYRIDGAHLTKM------SEYKGPVTDVFYKETSYTTTIKPVSYKLDGVT 1865
HY + L +DG + K+ + + D Y ++ P+ +D
Sbjct 1205 HYQTNIYSQNL-CVDGFGVNKIQPWTNDALNTICIKDADY-NAKVEISVTPIKNTVDTTP 1262
Query 1866 YTE--IEPKLDGYYKKDNAYYTEQPIDLV 1892
E ++ KL+ + DN + + +D V
Sbjct 1263 KEEFVVKEKLNAFLVHDNVAFYQGDVDTV 1291
Score = 47.7 bits (112), Expect = 0.006, Method: Composition-based stats.
Identities = 80/540 (15%), Positives = 155/540 (29%), Gaps = 80/540 (15%)
Query 176 ELNGGAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHE 235
+ GG VT Y D CG DG P+ L + +D+ H
Sbjct 107 KRGGGNVT-YTDQYLCGADGKPV------------MSEDLWQFVDHFGENE-EIIINGHT 152
Query 236 HEIAWFTERSDKSYEHQTPFEIKSA--KKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKT 293
+ AW T+R Y+ Q I+ D V + +VK K
Sbjct 153 YVCAWLTKRKPLDYKRQNNLAIEEIEYVHGDALHTLRNGSVLEMAKEVKT----SSKVVL 208
Query 294 EGFMGRIRSVYPVASPQECNNM--------HLSTLMKCNHCDEVSWQTCDFLKATCEHCG 345
+ ++ V+ +N+ +S L++C C SW D+
Sbjct 209 SDALDKLYKVFGSPVMTNGSNILEAFTKPVFISALVQCT-CGTKSWSVGDWTG------- 260
Query 346 TENLVIEGPTTCGYLPTNAVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRC 405
++C + +N + C + + G + G +
Sbjct 261 -------FKSSCCNVISNKL----CVVPGNVKPGDAVITTQ-----------QAGAGIKY 298
Query 406 FGGCVFAYVGCYNKRAYWVPRASADIGSGHTGITGDNVETLNEDLLEILSRERVNINIVG 465
F G +V + W A + T E +N + N+
Sbjct 299 FCGMTLKFVANIEGVSVWRVIALQSVDCFVASSTFVEEEHVNRM-------DTFCFNVRN 351
Query 466 DFHLNEEVAIILASFSAST-----SAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKG- 519
+A++ A +++ S ID + + I + V K + + G
Sbjct 352 SVTDECRLAMLGAEMTSNVRRQVASGVIDISTGW-FDVYDDIFAESKPWFVRKAEDIFGP 410
Query 520 AWNIGQQRSVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSLR 579
W+ S L L + ++SI + +I L L+
Sbjct 411 CWS--ALASALKQLKVTTGELVRFVKSICNSAVAVVGGTIQILASVPEKFLNAFDVFVTA 468
Query 580 L---VDAMVYTSDLLT---NSVIIMAYVTGGLVQQTSQWLSNLLGTTVEKLRPIFEWIEA 633
+ D V T + + V + LV+ + L + + K++ + +
Sbjct 469 IQTVFDCAVETCTIAGKAFDKVFDYVLLDNALVKLVTTKLKGVRERGLNKVKYATVVVGS 528
Query 634 KLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQV 693
++ + +L +G V D + ++ + V
Sbjct 529 TEEVKSSRVERSTAVLTIANNYSKLFDEGYTVVIGDVAYFVSDGYFRLMASPNSVLTTAV 588
Score = 46.6 bits (109), Expect = 0.012, Method: Composition-based stats.
Identities = 69/490 (14%), Positives = 149/490 (30%), Gaps = 76/490 (16%)
Query 528 SVLTPLCGFPSQAAGVIRSIFARTLDAANHSIPDLQRAAVTILDGISEQSL-RLVDAMVY 586
+V PL F G F T+ + +L+ A + + D I+E L +D +
Sbjct 587 AVYKPLFAFNVNVMGTRPEKFPTTV-----TCENLESAVLFVNDKITEFQLDYSIDVIDN 641
Query 587 TSDLLTNSVIIMAYVTGGLVQQTSQWLSNLLGTT-----VEKLRPIFEWIEAKLSAGVEF 641
+ N + + V + + + + + +A + A
Sbjct 642 EIIVKPNISLCVPLYVRDYVDKWDDFCRQYSNESWFEDDYRAFISVLDITDAAVKAAESK 701
Query 642 ---------------LKDAWEILKFLITGVFDI------------VKGQIQVASDNIKDC 674
+ D +I +I V + +G + + K
Sbjct 702 AFVDTIVPPCPSILKVIDGGKIWNGVIKNVNSVRDWLKSLKLNLTQQGLLGTCAKRFKRW 761
Query 675 VKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLLMPLK 734
+ ++ N L+ + V I G ++ + +I + + + + + L P
Sbjct 762 LGILLEAYNAFLDTVVSTVKIGGLTFKTYAFDKPYIVIRDIVCKVENKTEAEWIELFPHN 821
Query 735 APKEV-----TFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLM 789
+ + + T EEV L + E F G ++ +
Sbjct 822 DRIKSFSTFESAYMPIADPTHFDIEEVELLDAE----------FVEPGCGGILAVIDEHV 871
Query 790 LLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-TVWEVQGYKNVRITFEL-D 847
+ KD Y S G F G V+F +D V +++ V++ FE D
Sbjct 872 FYK-KDGVYYP--SNGTNILPVAFTKAAGG---KVSFSDDVEVKDIEPVYRVKLCFEFED 925
Query 848 ERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFY 907
E++ V + + + + L V N+ T+Y
Sbjct 926 EKLVDVCEKAIG-----KKIKHEGDWDSFCKTIQSALS-VVSCYVNLP---------TYY 970
Query 908 LFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGAS 967
++D+ G + S + S +P ++ + ++ + + ++
Sbjct 971 IYDEEGGNDLSLPVMISEWPLSVQQAQQEATLPDIAEDVVDQVEEVNSIFDIETVDVKHD 1030
Query 968 AETVRVEEEE 977
+ EE
Sbjct 1031 VSPFEMPFEE 1040
>sp|P0C6F6|R1A_BC512 Replicase polyprotein 1a OS=Bat coronavirus
512/2005 OX=693999 GN=1a PE=3 SV=1
Length=4128
Score = 2590 bits (6712), Expect = 0.0, Method: Composition-based stats.
Identities = 784/2391 (33%), Positives = 1229/2391 (51%), Gaps = 132/2391 (6%)
Query 2012 GMDNLACESQQPTSEEVVE-NPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHE 2070
G+D+ C P + VV N T+ + V +L
Sbjct 1841 GLDDGNCVHGLPLVDRVVSVNGTVIITNVGDTPGKPVVATENLLLDGVSYTVFQDSTTGV 1900
Query 2071 DLMAAYVENTSIT----IKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQA 2126
+ + + + KP +L+++ + + + P ++ FL
Sbjct 1901 GHYTVFDKEAKLMFDGDVLKPCDLNVSPVTSVVVCNNKKIVVQDPVKRVELDASKFLDTM 1960
Query 2127 AITTSNCAKRL--AQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPT---TIAKNSVK 2181
+ + R + Y+F+LL K + ++ A +P I K SVK
Sbjct 1961 NVASEKFFTFGDFVSRNIIVLIVYLFSLLAICFRALKKRDMKVMAGVPERTGIILKRSVK 2020
Query 2182 SVAKLCLDAGINYVKSPKFSKL-FTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYC 2240
NY F +L F L S+ L +L + F + + G P C
Sbjct 2021 ----------YNYKALKFFFRLKFQYIKVFLKFSLVLYTLYALMFMF-IRFTPVGTP-IC 2068
Query 2241 NGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGL 2300
+ Y NS+ D+C C ICL G + L + I + L IL L
Sbjct 2069 KRYTDGYANST-FDKNDYCGN-VLCKICLYGYEELSDFTHTRVIWQHLKD-PLIGNILPL 2125
Query 2301 AAEWVLAYMLFTKFFYLLGLSAIMQVFF--GYFASHFISNSWLMWFIISIVQMAPVSAMV 2358
+++ ++F FF +G++ + + A + N WL+ + P ++M
Sbjct 2126 F--YLVFLIIFGGFFVRIGITYFIMQYINAAGVALGYQDNVWLL-------HLLPFNSMG 2176
Query 2359 RMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGG 2418
+ + I H++ GC +C+ C K + TRV TI+ G+ +SFYV ANGG
Sbjct 2177 NIIVVAFIVTRILLFLKHVLFGCDKPSCIACSKSAKLTRVPLQTILQGVTKSFYVNANGG 2236
Query 2419 RGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGAL 2478
+ FCK HN+ C++CD++ G TFI+D +A +LS K + PT ++ I+D V NG
Sbjct 2237 KKFCKKHNFFCVDCDSYGYGCTFINDVIAPELSNVTKLNVIPTGPATIIIDKVEFSNGFY 2296
Query 2479 HLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYY 2538
+LY K + + D L+ N + + +VF+ S + + K+A VY+
Sbjct 2297 YLYSGSTFWKYNFDITEAKYACKDVLKNCN----ILTDFVVFNN-SGSNVTQVKNACVYF 2351
Query 2539 SQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELA 2598
SQL+C+PI L+D AL++ + + S + A+V+ S +F + +
Sbjct 2352 SQLLCKPIKLVDSALLASLN--VDFSANLHKAFVEVLSNSFGKDLSNCSNM--------- 2400
Query 2599 KGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKVE 2658
+ R+ + +DV ++ + +H D+ ++ S NN +++Y K E
Sbjct 2401 -------------NECRESLGLSDVPEEEFSAAVSEAHRYDVLISDVSFNNLIVSYAKPE 2447
Query 2659 -NMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPF 2717
+ D+ C+ A+ +N V NV ++W KD+++LSE+ RK I K I F
Sbjct 2448 EKLAVHDIANCMRVGAKVVNHNVLTKDNVPVVWLAKDFIALSEEARKYIVRTTKTKGINF 2507
Query 2718 RLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHD 2777
LT R + + T ++ K G + + F + + L L+ + + L
Sbjct 2508 MLTFNDRRMHLTIPTISVANKKGAGLPSLFTRLY--SFFWHLCVLIVVLFVATSLLDFSA 2565
Query 2778 GYTNEI-IGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGS-YKNDKSCPVVAAII 2835
T++ +K I++GV + DC N F+ W + + GS N + CP+V
Sbjct 2566 QVTSDTQYDFKYIENGVLKVFEKPLDCVHNAFVNFNEWHNAKFGSIPTNSRRCPIVVGTS 2625
Query 2836 TREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAE 2895
+PG+P V + G L F +C+ L + +C+ +
Sbjct 2626 DEV--RYIPGVPAGVF--LYGKSLIFAMSTIFGTSGLCFDDRGLTD-----PDSCIFNSA 2676
Query 2896 CTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEG-SVRVVT 2954
CT G+ V YCY +++ + YS L P + Y LMDG+ I P G +R +
Sbjct 2677 CTTLSGIGGRNV-YCYREGVVDNAKLYSSLLPHSYYRLMDGNHIVLPEIITRGFGIRTIK 2735
Query 2955 TFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQP 3014
T YCR G C S+ G+C+ +V + S CG +L+ N+
Sbjct 2736 TQAMTYCRTGECIDSQAGVCVGLDRFFVYSKT---PGSDYVCGTGFFSLLFNVIGMFSNS 2792
Query 3015 VGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPA 3074
+ +S ++ ++A A + F KF+R+FG+ + V + L +++ +V
Sbjct 2793 IPVTVMSGQILLNCVVAFTAVMACFAFTKFKRLFGDMSFGVLSVGLCTVVNNL-SYVVTQ 2851
Query 3075 YSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFF 3134
S Y+ Y T S++ H+ + + + P+W+ Y+ C L+ F
Sbjct 2852 NSIGMLAYATLYFLCTK--GVRYSWVWHVGFAISYCFLAPWWVVLAYLICALLEFLPNLF 2909
Query 3135 NNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKY 3193
+ + +F G F +FE AA TF+L+ Y KL + + + +Y A YN+YKY
Sbjct 2910 KLKVSTQ-LFEGDKFVGSFESAASGTFVLDMHSYQKLANS--ISTEKLKQYCASYNRYKY 2966
Query 3194 FSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKV 3253
+SG+ YR A HLAKA++DF+N D LY PP S S LQ+G RKMA PSG V
Sbjct 2967 YSGSASEADYRLACFAHLAKAMSDFANDHMDKLYTPPTVSYNST-LQAGLRKMAQPSGIV 3025
Query 3254 EGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGNV 3313
EGC+V+V+ G TLNGLWL DTV CPRHVI + + +Y+ + H+F + +GN+
Sbjct 3026 EGCIVRVSYGNLTLNGLWLGDTVICPRHVIASNTTNV-IDYDHAMSLVRLHNFSISSGNM 3084
Query 3314 QLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPN 3373
L VI SM+ LL +KV+ SN TP Y + ++PG +F++LACY+GS +GVY MR N
Sbjct 3085 FLGVISASMRGTLLHIKVNQSNVNTPNYTYKVLKPGDSFNILACYDGSAAGVYGVNMRTN 3144
Query 3374 HTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQA 3433
+TI+GSF++G+CGS G+NI+ V FCYMHH+EL +G H G+D++G YG + D+ T Q
Sbjct 3145 YTIRGSFISGACGSPGYNINNGVVEFCYMHHLELGSGCHVGSDMDGTMYGKYEDQPTLQI 3204
Query 3434 AGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPL 3493
G +T NV +WLY A+INGDRW+L+ + ++ +N A++ L +VD L
Sbjct 3205 EGASNLVTENVCSWLYGALINGDRWWLSSVSVGVDTYNEWALRNGMTALK--NVDCFSLL 3262
Query 3494 SAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ-GKFKKI 3552
A+TG+ V + A++++L N G++ILG T L DEFT +VV+Q GVT Q GK +
Sbjct 3263 VAKTGVDVGRLLASIQKLHGN-FGGKSILGCTSLCDEFTLSEVVKQMYGVTLQSGKVSRA 3321
Query 3553 VKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAF 3612
+ L FL L + S F++ P L I+ ++ MLLVKHK F
Sbjct 3322 FRNASIVCCLLFLF----LSEMLNHSKLFWINPGYITPVFLAIIVASSALMLLVKHKLLF 3377
Query 3613 LCLFLLPSLATVAYFNMV--YMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLI 3670
L L+LLPSL V+ +N+ Y ++++ + G+ + + + ++
Sbjct 3378 LQLYLLPSLCIVSGYNIFKDYHFYTYMLEEFDY----KVPFGGFNVTGVLNISLCCFVMG 3433
Query 3671 LMTARTVYDDAARRVW-TLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIM 3729
L T R + +++ ++ V+T++Y YY + + +S +NY + T
Sbjct 3434 LHTFR--FLQTPNKIFSYVVAVLTVLYTYYYS---TDVLGLILTSMSGFTNYWFIGTATY 3488
Query 3730 FLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYD 3789
LA V + L + + ++ ++ +Y LGYC C Y+G +NR+ +LTLG Y+
Sbjct 3489 KLATY-----VLPHTSLLDSFDAIKAVVFLYLLLGYCNCVYYGSLYWINRFCKLTLGCYE 3543
Query 3790 YLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVL 3849
+ VS EF+YM + GL P DA L++KL+G+GG+ IK+++VQSK++D+KCT+VVL
Sbjct 3544 FKVSAAEFKYMVANGLRAPTGVFDALILSLKLIGVGGRKTIKISSVQSKLTDLKCTNVVL 3603
Query 3850 LSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCE 3909
L L + + ++S+ WA CV LHN I L D A E +++LL+ LS A ++ L +
Sbjct 3604 LGCLSNMNIAANSREWAYCVDLHNKINLCNDAEAAQEMLLALLAFFLSKNSAFGVDELLD 3663
Query 3910 EMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFD 3969
++ + LQ++A+ + +LPSY AY TA+++YE A+ANG ++K+L+ ++NVAKSEFD
Sbjct 3664 SYFNDSSVLQSVAATYVNLPSYLAYETARQSYEDALANGSPPQLVKQLRHAMNVAKSEFD 3723
Query 3970 RDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNA 4029
R+A+ QRKL++MA+QA +QMYK+AR+ ++++KV SAM ++LF MLR+LD +++ I++ A
Sbjct 3724 REASTQRKLDRMAEQAASQMYKEARAVNRKSKVVSAMHSLLFGMLRRLDMSSVDTILSLA 3783
Query 4030 RDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIVQLS 4089
+DG VPL+IIP +A KL +VV D +Y YA +W + + D D K V
Sbjct 3784 KDGVVPLSIIPAVSATKLNIVVSDIESYSKIQREGCVHYAGVIWSVVDIKDNDGKPVHAK 3843
Query 4090 EINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYY 4149
E+ N +LAWPL + R +KLQNNE+ P ++Q A D NAL Y
Sbjct 3844 EVVTSNVESLAWPLFLNCER---IIKLQNNEIIPSKIKQRPIKAEGE-GVVADGNAL--Y 3897
Query 4150 NNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIK 4209
+N G F+ A +SD DLK ++ G+ I ELEPPC+F+ + P GP VKYLYF++
Sbjct 3898 SNEGGRTFMYAFISDKPDLKVVKWEFDGGSNAI--ELEPPCKFLVEAPSGPVVKYLYFVR 3955
Query 4210 GLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKDYLASGGQPIT 4269
LNNL RG VLG + ATVRLQAG TE NS++L+ CAFAVDP K Y D + SG +P+
Sbjct 3956 NLNNLRRGAVLGFIGATVRLQAGKQTEQATNSSLLTLCAFAVDPPKTYLDAVKSGHRPVG 4015
Query 4270 NCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQI 4329
NCVKML +G GQAIT EA+ +Q+S+GGAS CLYCR H++HP+ GFC L+GKYVQ+
Sbjct 4016 NCVKMLANGSGNGQAITNGVEASTNQDSYGGASVCLYCRAHVEHPDMDGFCKLRGKYVQV 4075
Query 4330 PTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRV 4380
P DP+ F L NTVC VCG W+ GC+CD+ ++QS D S +LN
Sbjct 4076 PLGTL-DPIRFVLENTVCKVCGCWQANGCTCDR---AVIQSVD-SGYLNEC 4121
Score = 270 bits (689), Expect = 5e-70, Method: Composition-based stats.
Identities = 83/361 (23%), Positives = 132/361 (37%), Gaps = 38/361 (11%)
Query 1538 SLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFV 1597
+L E K ++V T D + HT + S TYGQQ G ++ VT +KP + V
Sbjct 1634 TLFEAKPVQVVVTQDQRSFHTVELSTSQTYGQQLGDCVVEDKKVTNLKPVSKDK--VVSV 1691
Query 1598 LPSDDTLRSEAF---EYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLS 1654
+P+ D + F +HTLD + + V G ++ +DNNC+++
Sbjct 1692 VPNVDWDKHYGFVDAGIFHTLDHTMFVFDNN-----------VVNGKRVLRTSDNNCWIN 1740
Query 1655 SVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQ 1714
+V L LQ KF LQ+ + GD A F + + GE D T+ + +
Sbjct 1741 AVCLQLQFANAKFKPKGLQQLWESYCTGDVAMFVHWLYWITGVEKGEPSDAENTLNIISR 1800
Query 1715 HANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIP-CVCGRDATQY 1773
+ + +L C +T + V+ ++ LK G+ CV G
Sbjct 1801 FLKPQGSVEMLRATSTTCDGTCST----KRVVSTPVVNASVLKVGLDDGNCVHGLPLVDR 1856
Query 1774 LVQQESSFVMMSA---PPAEYKLQQGTFLCANEYT----GNYQCGHYTHITAKETLYRID 1826
+V + ++ + P + L YT GHYT + KE D
Sbjct 1857 VVSVNGTVIITNVGDTPGKPVVATENLLLDGVSYTVFQDSTTGVGHYT-VFDKEAKLMFD 1915
Query 1827 GAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPK--LDGYYKKDNAYY 1884
G L PVT V PV E++ LD ++
Sbjct 1916 GDVLKPCDLNVSPVTSVVVCNNKKIVVQDPV-------KRVELDASKFLDTMNVASEKFF 1968
Query 1885 T 1885
T
Sbjct 1969 T 1969
Score = 152 bits (385), Expect = 1e-34, Method: Composition-based stats.
Identities = 71/310 (23%), Positives = 114/310 (37%), Gaps = 22/310 (7%)
Query 1002 PVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAM 1061
V F Y N+ + + S N +VNAAN L HGGG+A AL+ T G +
Sbjct 1295 DVKPFLTYK----NIEFYQGE-LSALLSVNHDFVVNAANEQLSHGGGIAKALDDLTKGEL 1349
Query 1062 QKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDI 1121
Q S+ Y+ NG + VG L+ L+VVGP L KA F + +
Sbjct 1350 QVLSNQYVSRNGSIKVGSGVLIKCKE--HSILNVVGPRKGKHAAELLTKAYTFVFKQKGV 1407
Query 1122 LLAPLLSAGIFGAK---PLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLK----- 1173
L PLLS GIF L + CV + + + + L Q + +
Sbjct 1408 PLMPLLSVGIFKVPITESLAAFLACVGDRVCKCFCYTDKERLAIQNFVTSFQTEQPVEPL 1467
Query 1174 PRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFL--TNKLLL 1231
P ++ K + E ++ K + +L+ T+ + TN L
Sbjct 1468 PVIQEVKGVQLEKPVPDVKVENPCEPFRIEGDAKFYDLTPSMVQSLQVTRLVSFTNSDLC 1527
Query 1232 FADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSG-----DITCVVIPSKKAGGTT 1286
Q L G ++ + + G+ +T T V++P +
Sbjct 1528 LGSFVRDCDGYVQGSLGGAIANYKKSNPVLPAGNCVTLKCDGFISFTFVILPKEGDTNYE 1587
Query 1287 EMLSRALKKV 1296
+ +RA+ K
Sbjct 1588 KNFNRAIAKF 1597
Score = 65.1 bits (157), Expect = 4e-08, Method: Composition-based stats.
Identities = 38/195 (19%), Positives = 65/195 (33%), Gaps = 24/195 (12%)
Query 1626 ALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAA 1685
+ + GGL + + NNC++SS L+ LQ + ++ +Q AG +
Sbjct 1078 VKPDVFAFSYASYGGLKVLNQSSNNCWVSSALVQLQLTGL-LDSDEMQL----FNAGRVS 1132
Query 1686 NFCALILAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTT-----LT 1740
G LGDV + LL+ + S ++ C G + T
Sbjct 1133 PMVKRCYESQRAIFGSLGDVSACLESLLKDRDGMSITCTIDCGCGP-GVRVYENAIFRFT 1191
Query 1741 GVEAVMYMGTLSYDNLKTGVSIPCVCGRDATQYLVQQESSFVMM-SAPPAEYKLQQGTFL 1799
++ MG +C + + Q + + + A + L
Sbjct 1192 PLKTAFPMGR------------CLICSKTLMHTITQMKGTGIFCRDATALDVDTLVVKPL 1239
Query 1800 CANEYTGNYQCGHYT 1814
CA Y G GHY
Sbjct 1240 CAAVYVGAQDGGHYL 1254
Score = 56.2 bits (134), Expect = 2e-05, Method: Composition-based stats.
Identities = 55/364 (15%), Positives = 114/364 (31%), Gaps = 50/364 (14%)
Query 653 ITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQ 712
+ GV V + + A ++ F+D V +++ + + +
Sbjct 750 LNGVVVFVTKKFRKAGALLQKLYNAFLDTVTSFIKVAGVAFKYCATCVPKIVIN------ 803
Query 713 SKGLYRQCIRGKEQLQLLMPLKAPKEVTFLE-GDSHDTVLTSEEVVLKNGELEALETPVD 771
+ + LQ+ P E + + V ++ LE E
Sbjct 804 -GCYHTVTRLFAKDLQI------PTEDGVADFNTFNHCVFPVNPTRIETDSLELEEV--- 853
Query 772 SFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGED-T 830
F + G V ++ S G + F+ KGG VT ++
Sbjct 854 DFVEPGVDGKLVILDDYSFYSDGTNYYP---SDGKGVVASCFKKKGGGV---VTISDEVQ 907
Query 831 VWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDL 890
V + VR+ +E + D+ L + C E +++TL+ D+
Sbjct 908 VRTIDPVYKVRLEYEFE---DETLVKVC-----EKAIGTKLKVTGDWSNLLETLEKAMDV 959
Query 891 LTNMGIDLDEWSVATFYLFDDAG-----------EENFSSRMYCSFYPPDEEEEDDAECE 939
+ V ++++D+ G + SS F D+E + +
Sbjct 960 VR------QHLDVPDYFVYDEEGGTDLNLTIMVSQWPLSSDSEDDFKAVDDEPNANTDET 1013
Query 940 EEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTP 999
+ E + D +E V+ EE + + + +Q E++
Sbjct 1014 VDTFAEDVAETQNVQQDVTQDEVE-AVCDLVVKATEEGPIEHEELSEDQKEVQQALAFIE 1072
Query 1000 EEPV 1003
++PV
Sbjct 1073 DKPV 1076
Score = 40.4 bits (93), Expect = 0.93, Method: Composition-based stats.
Identities = 32/181 (18%), Positives = 49/181 (27%), Gaps = 42/181 (23%)
Query 180 GAVTRYVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIE--SKRGVYCCRDHEHE 237
G T VD CG DG P+ +++ + +
Sbjct 109 GGTTIPVDQFMCGADGAPV---------------IQEGDWTFMDYFQDSNQFTLNGITYV 153
Query 238 IAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVI-QPRVEKKKTEG- 295
AW +R Y Q I+ + V + +K P+V K
Sbjct 154 KAWDVDRKPNDYAKQNVTCIRRITYITDH-----RHVLADGTTMKTARHPKVNKSVVLDS 208
Query 296 ------------FMGRIRSVYPVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATCEH 343
FMG + V ++ H L+ C C W D+ K
Sbjct 209 PFDQIYKEVGSPFMGNGSTF--VEMLKDPAFFH--ALITCE-CGRSEWTVGDW-KGYNSL 262
Query 344 C 344
C
Sbjct 263 C 263
>sp|P0C6V6|R1A_PEDV7 Replicase polyprotein 1a OS=Porcine epidemic
diarrhea virus (strain CV777) OX=229032 GN=1a PE=1 SV=1
Length=4117
Score = 2568 bits (6655), Expect = 0.0, Method: Composition-based stats.
Identities = 784/2462 (32%), Positives = 1221/2462 (50%), Gaps = 155/2462 (6%)
Query 1968 VWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMD---NLACESQQPT 2024
+W F + L + +P D+ N+ +L+
Sbjct 1753 MWESYCTGDVAMFVHWLYWLTGVDKGQPSDSENALNMLSKYIVPAGSVTIERVTHDGCCC 1812
Query 2025 SEEVVENPTIQKEVIECDVK------TTEVVGNVILKPSDEGVKVTQELG--HEDLMAAY 2076
S+ VV P + V++ V+ +G V++ +G + +G +
Sbjct 1813 SKRVVTAPVVNASVLKLGVEDGLCPHGLNYIGKVVVV---KGTTIVVNVGKPVVAPSHLF 1869
Query 2077 VENTSITIKKPNELSLALGLKTIATHGIAAINS----VPWSKILAYVKPFLGQAAITTSN 2132
++ S T N + +G T+ HG ++ VP ++ V +
Sbjct 1870 LKGVSYTTFLDNG-NGVVGHYTVFDHGTGMVHDGDAFVPGDLNVSPVTNVVVSEQTAVVI 1928
Query 2133 CAKRLAQRV----FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTI-------AKNSVK 2181
+ + M Y F F + + + + K VK
Sbjct 1929 KDPVKKAELDATKLLDTMNYASERFFSFGDFMSRNLITVFLYILSILGLCFRAFRKRDVK 1988
Query 2182 SVAKLCLDAGINYVKSPK--------FSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSN 2233
+A + GI KS + F KL +L + + +
Sbjct 1989 VLAGVPQRTGIILRKSMRYNAKALGVFFKLKLYWFKVLGKFSLGIYALYALLFMTIRFTP 2048
Query 2234 FGAPSYCNGVRELYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKL 2293
G+P C+ V Y NSS ++C S C +CL G L + + + + L
Sbjct 2049 IGSP-VCDDVVAGYANSS-FDKNEYC-NSVICKVCLYGYQELSDFSHTQVVWQHLRD-PL 2104
Query 2294 DLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVF-FGYFASH--FISNSWLMWFIISIVQ 2350
++ Y+ F F + + AI F F Y S F+ +WF+ Q
Sbjct 2105 IGNVMPFF------YLAFLAIFGGVYVKAITLYFIFQYLNSLGVFLGLQQSIWFL----Q 2154
Query 2351 MAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRS 2410
+ P + F + H+ GC ++C+ C K R RV TI G +S
Sbjct 2155 LVPFDVFGDEIVVFFIVTRVLMFIKHVCLGCDKASCVACSKSARLKRVPVQTIFQGTSKS 2214
Query 2411 FYVYANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDS 2470
FYV+ANGG FCK HN+ CLNCD++ G TFI+D +A ++ K + PT ++ ++D
Sbjct 2215 FYVHANGGSKFCKKHNFFCLNCDSYGPGCTFINDVIATEVGNVVKLNVQPTGPATILIDK 2274
Query 2471 VAVKNGALHLYFDKAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESA 2530
V NG +LY K S + + L+ S+ + IVF+ + +
Sbjct 2275 VEFSNGFYYLYSGDTFWKYNFDITDSKYTCKEALK----NCSIITDFIVFNNNG-SNVNQ 2329
Query 2531 SKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALV 2590
K+A VY+SQ++C+P+ L+D AL++ + S + + A+V S +F + +
Sbjct 2330 VKNACVYFSQMLCKPVKLVDSALLASL--SVDFGASLHSAFVSVLSNSFGKDLSSCNDM- 2386
Query 2591 ATAHSELAKGVALDGV-LSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNN 2649
+ + D V L TF +A + +H D+ +T S NN
Sbjct 2387 ----QDCKSTLGFDDVPLDTFNAAVAE------------------AHRYDVLLTDMSFNN 2424
Query 2650 FMLTYNKVENMTP-RDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRS 2708
F +Y K E P D+ C+ A+ +N V ++ ++W V+D+++LSE+ RK I
Sbjct 2425 FTTSYAKPEEKFPVHDIATCMRVGAKIVNHNVLVKDSIPVVWLVRDFIALSEETRKYIIR 2484
Query 2709 AAKKNNIPFRLTCATTRQVVNVITTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVM 2768
K I F LT R + T I+ K G + + K+ LC+ +IV
Sbjct 2485 TTKVKGITFMLTFNDCRMHTTIPTVCIANKKGAGLPSFSKVKKFFWFLCL------FIVA 2538
Query 2769 PVHTLSIHDGYT----NEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGS-YK 2823
LS D T + +K I+ G + + C N FD W + G
Sbjct 2539 AFFALSFLDFSTQVSSDSDYDFKYIESGQLKTFDNPLSCVHNVFINFDQWHDAKFGFTPV 2598
Query 2824 NDKSCPVVAAIITREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYS 2883
N+ SCP+V + + VPG+P V + G L F +C+ S + +
Sbjct 2599 NNPSCPIVVGV--SDEARTVPGIPAGVY--LAGKTLVFAINTIFGTSGLCFDASGVAD-- 2652
Query 2884 DFATSACVLAAECTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPN 2943
AC+ + CT G V YCY L+EG+ YSEL P + Y ++DG+ + P
Sbjct 2653 ---KGACIFNSACTTLSGLGGTAV-YCYKNGLVEGAKLYSELAPHSYYKMVDGNAVSLPE 2708
Query 2944 TYLEG-SVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMN 3002
G +R + T YCR G C +S G+C +V N E + S CG
Sbjct 2709 IISRGFGIRTIRTKAMTYCRVGQCVQSAEGVCFGADRFFVYNAE---SGSDFVCGTGLFT 2765
Query 3003 LIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLF 3062
L+ N+ + + V +S ++ IIA + + F KF+R+FG+ + V
Sbjct 2766 LLMNVISVFSKTVPVTVLSGQILFNCIIAFVAVAVCFLFTKFKRMFGDMSVGVFTVGACT 2825
Query 3063 LMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYV 3122
L++ + +V + Y+ Y T ++ HL + + I P+W+ +Y
Sbjct 2826 LLN-NVSYIVTQNTLGMLGYATLYFLCTK--GVRYMWIWHLGFLISYILIAPWWVLMVYA 2882
Query 3123 FCISLKHCHWFFNNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQY 3181
F + F + + +F G F +FE AA TF+L+ Y +L + + +
Sbjct 2883 FSAIFEFMPNLFKLKVSTQ-LFEGDKFVGSFENAAAGTFVLDMHAYERLANS--ISTEKL 2939
Query 3182 NRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQS 3241
+Y + YNKYKY+SG+ YR A HLAKA+ D++++ D LY PP S S LQ+
Sbjct 2940 RQYASTYNKYKYYSGSASEADYRLACFAHLAKAMMDYASNHNDTLYTPPTVSYNST-LQA 2998
Query 3242 GFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRK 3301
G RKMA PSG VE C+V+V G LNGLWL D V CPRHVI ++ +Y+ L
Sbjct 2999 GLRKMAQPSGVVEKCIVRVCYGNMALNGLWLGDIVMCPRHVIASSTT-STIDYDYALSVL 3057
Query 3302 SNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGS 3361
H+F + +GNV L V+ +M+ LL++KV+ +N TPKY + ++PG++F++LACY+G+
Sbjct 3058 RLHNFSISSGNVFLGVVSATMRGALLQIKVNQNNVHTPKYTYRTVRPGESFNILACYDGA 3117
Query 3362 PSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKF 3421
+GVY MR N+TI+GSF+NG+CGS G+NI+ V FCY+H +EL +G H G+DL+G
Sbjct 3118 AAGVYGVNMRSNYTIRGSFINGACGSPGYNINNGTVEFCYLHQLELGSGCHVGSDLDGVM 3177
Query 3422 YGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEP 3481
YG + D+ T Q G + T NVLA+LYAA+ING W+L+ ++ FN A+
Sbjct 3178 YGGYEDQPTLQVEGASSLFTENVLAFLYAALINGSTWWLSSSRIAVDRFNEWAVHNGMTT 3237
Query 3482 LTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCS 3541
+ + D L+A+TG+ V + A+++ L +N G+ ILG T L DEFT +VVRQ
Sbjct 3238 VG--NTDCFSILAAKTGVDVQRLLASIQSLHKN-FGGKQILGHTSLTDEFTTGEVVRQMY 3294
Query 3542 GVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAAC 3601
GV QG + + + + +L+ + + ++ FF+V P + +++
Sbjct 3295 GVNLQGGY--VSRACRNVLLVGSFLT-FFWSELVSYTKFFWVNPGYVTPMFACLSLLSSL 3351
Query 3602 AMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVM 3661
M +KHK F +FL+P+L + N+ + + + SL G+ + V
Sbjct 3352 LMFTLKHKTLFFQVFLIPALIVTSCINLAFDVEVY--NYLAEHFDYHVSLMGFNAQGLVN 3409
Query 3662 YASALVLLILM---TARTVYDDAARRVWTLMNVITLVYKVYYGNA-LDQAISMWALVISV 3717
V+ IL T R A V ++ ++T Y +Y + L A++++A SV
Sbjct 3410 IFVCFVVTILHGTYTWRFFNT-PASSVTYVVALLTAAYNYFYASDILSCAMTLFA---SV 3465
Query 3718 TSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLL 3777
T N V + + + V++ + + P ++ +M Y LGY CC++G+
Sbjct 3466 TGN--WFVGAVCY--KVAVYMALRF-PTFVAIFGDIKSVMFCYLVLGYFTCCFYGILYWF 3520
Query 3778 NRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQS 3837
NR+F++++GVYDY VS EF+YM + GL P ++D+ L+ KL+GIGG+ IK+++VQS
Sbjct 3521 NRFFKVSVGVYDYTVSAAEFKYMVANGLRAPTGTLDSLLLSAKLIGIGGERNIKISSVQS 3580
Query 3838 KMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLS 3897
K++D+KC++VVLL L + V ++S WA CV LHN I L D +A E +++LL+ LS
Sbjct 3581 KLTDIKCSNVVLLGCLSSMNVSANSTEWAYCVDLHNKINLCNDPEKAQEMLLALLAFFLS 3640
Query 3898 MQGAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKL 3957
A ++ L E ++ + LQ++AS + LPSY Y A++ YE AV NG ++K+L
Sbjct 3641 KNSAFGLDDLLESYFNDNSMLQSVASTYVGLPSYVIYENARQQYEDAVNNGSPPQLVKQL 3700
Query 3958 KKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKL 4017
+ ++NVAKSEFDR+A+ QRKL++MA+QA QMYK+AR+ ++++KV SAM ++LF MLR+L
Sbjct 3701 RHAMNVAKSEFDREASTQRKLDRMAEQAAAQMYKEARAVNRKSKVVSAMHSLLFGMLRRL 3760
Query 4018 DNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQ 4077
D +++ I+N A+DG VPL++IP +A KL +V D +Y YA +W I
Sbjct 3761 DMSSVDTILNLAKDGVVPLSVIPAVSATKLNIVTSDIDSYNRIQREGCVHYAGTIWNIID 3820
Query 4078 VVDADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQ 4137
+ D D K+V + E+ N+ +L+WPL++ R VKLQNNE+ P L+Q S A
Sbjct 3821 IKDNDGKVVHVKEVTAQNAESLSWPLVLGCER---IVKLQNNEIIPGKLKQRSIKAEGDG 3877
Query 4138 TACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTP 4197
A YNN G F+ A +SD DL+ ++ G TI ELEPP +F+ D+P
Sbjct 3878 IV---GEGKALYNNEGGRTFMYAFISDKPDLRVVKWEFDGGCNTI--ELEPPRKFLVDSP 3932
Query 4198 KGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAY 4257
G ++KYLYF++ LN L RG VLG + ATVRLQAG TE NS++L+ CAFAVDPAK Y
Sbjct 3933 NGAQIKYLYFVRNLNTLRRGAVLGYIGATVRLQAGKQTEQAINSSLLTLCAFAVDPAKTY 3992
Query 4258 KDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPK 4317
D + SG +P+ NCVKML +G GQA+T EA+ +Q+S+GGAS CLYCR H++HP+
Sbjct 3993 IDAVKSGHKPVGNCVKMLANGSGNGQAVTNGVEASTNQDSYGGASVCLYCRAHVEHPSMD 4052
Query 4318 GFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFL 4377
GFC LKGKYVQ+P DP+ F L N VC VCG W GC+CD+ +MQS D + +L
Sbjct 4053 GFCRLKGKYVQVPLGTV-DPIRFVLENDVCKVCGCWLSNGCTCDR---SIMQSTDMA-YL 4107
Query 4378 NR 4379
N
Sbjct 4108 NE 4109
Score = 245 bits (625), Expect = 1e-62, Method: Composition-based stats.
Identities = 77/325 (24%), Positives = 120/325 (37%), Gaps = 33/325 (10%)
Query 1543 KTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPSDD 1602
K++ + T D ++ V+ + TYGQQ GP ++ VT KP V V+P+ +
Sbjct 1631 KSVVIKVTEDTRSVKAVKVESTATYGQQIGPCLVNDTVVTDNKPVVADV--VAKVVPNAN 1688
Query 1603 TLRSEAFEYYHTLDESFLGRYMSALNHTK-KWKFPQVGGLTSIKWADNNCYLSSVLLALQ 1661
F+ L+HT + V G IK DNNC+++ L LQ
Sbjct 1689 WDSHYGFDKAGEF---------HMLDHTGFTFPSEVVNGRRVIKTTDNNCWVNVTCLQLQ 1739
Query 1662 QLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQH---ANL 1718
+F + LQ + GD A F + + G+ D + L ++ A
Sbjct 1740 FARFRFKSAGLQAMWESYCTGDVAMFVHWLYWLTGVDKGQPSDSENALNMLSKYIVPAGS 1799
Query 1719 ESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIP-CVCGRDATQYLVQQ 1777
+ +RV + C C ++ T V A + LK GV C G + +V
Sbjct 1800 VTIERVTHDGC-CCSKRVVTAPVVNASV---------LKLGVEDGLCPHGLNYIGKVVVV 1849
Query 1778 ESSFVMMSAPPAEYKLQQGTFLCANEYT-----GNYQCGHYTHITAKETLYRIDGAHLTK 1832
+ + +++ FL YT GN GHYT + DG
Sbjct 1850 KGTTIVV-NVGKPVVAPSHLFLKGVSYTTFLDNGNGVVGHYTVFDHGTGMVH-DGDAFVP 1907
Query 1833 MSEYKGPVTDVFYKETSYTTTIKPV 1857
PVT+V E + PV
Sbjct 1908 GDLNVSPVTNVVVSEQTAVVIKDPV 1932
Score = 217 bits (553), Expect = 3e-54, Method: Composition-based stats.
Identities = 92/326 (28%), Positives = 142/326 (44%), Gaps = 28/326 (9%)
Query 988 QSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGG 1047
+ + P + E V F Y NV D + +VNAAN L HGG
Sbjct 1275 TAPLVPAVDSVVEPVVKPFYSYK----NVDFYQGDFSDLVK-LPCDFVVNAANEKLSHGG 1329
Query 1048 GVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQ 1107
G+A A++ T G +QK S+DYIK +GP+ VG +L L K +VVGP
Sbjct 1330 GIAKAIDVYTKGMLQKCSNDYIKAHGPIKVGRGVMLEA--LGLKVFNVVGPRKGKHAPEL 1387
Query 1108 LLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMD 1167
L+KA F + + L PL+S GIF +SL + V + + ++
Sbjct 1388 LVKAYKSVFANSGVALTPLISVGIFSVPLEESLSAFLACVGDRHCKCFCYGDKEREAIIK 1447
Query 1168 YLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPV--DVKP-KIKA------CIDEVTTT 1218
Y+D L V+A +E +T + + + V QKPV + +P +I+ C E +
Sbjct 1448 YMDGL---VDAIFKEALVDTTPVQEDVQQVSQKPVLPNFEPFRIEGAHAFYECNPEGLMS 1504
Query 1219 LEETKFL--TNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYM-VGDVITSG----- 1270
L K + TN L F + GK +D + E ++ +K + G+ +T
Sbjct 1505 LGADKLVLFTNSNLDFCSV-GKCLNDVTSGALLEAINVFKKSNKTVPAGNCVTLDCANMI 1563
Query 1271 DITCVVIPSKKAGGTTEMLSRALKKV 1296
IT VV+P + +RA+ KV
Sbjct 1564 SITMVVLPFDGDANYDKNYARAVVKV 1589
Score = 63.9 bits (154), Expect = 9e-08, Method: Composition-based stats.
Identities = 49/260 (19%), Positives = 83/260 (32%), Gaps = 29/260 (11%)
Query 1632 KWKFPQVGGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALI 1691
+ F GGL ++ + NNC+++S L+ LQ L + + A AG
Sbjct 1072 AFDFVSYGGLKVLRQSHNNCWVTSTLVQLQLLGIVDDP-----AMELFSAGRVGPMVRKC 1126
Query 1692 LAYSNKTVGELGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTL 1751
+G LGDV + L + +L + K +VVC CG G + T
Sbjct 1127 YESQKAILGSLGDVSACLESLTK--DLHTLKITCSVVCG-CGTGERIYEG---CAFRMTP 1180
Query 1752 SYDNLKTGVSIPCVCGRDATQYLVQQESSFVMMSAPPA-EYKLQQGTFLCANEYTGNYQC 1810
+ + C + + + A LCA + G
Sbjct 1181 TLEPF--PYGACAQCAQVLMHTFKSIVGTGIFCRDTTALSLDSLVVKPLCAAAFIGK-DS 1237
Query 1811 GHYT--HITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTE 1868
GHY A + + + V DV + P+ +D V
Sbjct 1238 GHYVTNFYDAAMAIDGYGRHQIKYDTLNTICVKDVNWTA--------PLVPAVDSVVEPV 1289
Query 1869 IEPKLDGYYKKDNAYYTEQP 1888
++P +Y N + +
Sbjct 1290 VKP----FYSYKNVDFYQGD 1305
Score = 62.8 bits (151), Expect = 2e-07, Method: Composition-based stats.
Identities = 49/212 (23%), Positives = 72/212 (34%), Gaps = 43/212 (20%)
Query 172 ELTRELNGGAVTRYVDNNFCGPDGYPLD-----CIKDFLARAGKSMCTLSEQLDYIESKR 226
ELT GG + VD CG DG P+ DF A +S+
Sbjct 102 ELTFGRRGGNIVP-VDQYMCGADGKPVLQESEWEYTDFFA----------------DSED 144
Query 227 GVYCCRDHEHEIAWFTERSDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVI-Q 285
G + AW ERSD SY Q IKS T++ F + +KV
Sbjct 145 GQLNIAGITYVKAWIVERSDVSYASQNLTSIKSITYCSTYE-----HTFLDGTAMKVART 199
Query 286 PRVEKKKTEGFMGRIRSVYPVASPQECNN-----------MHLSTLMKCNHCDEVSWQTC 334
P+++K + ++Y +N + L +KC C W
Sbjct 200 PKIKKNVV--LSEPLATIYREIGSPFVDNGSDARSIIRRPVFLHAFVKCK-CGSYHWTVG 256
Query 335 DFLKATCEHCGTENLVIEGPTTCGYLPTNAVV 366
D+ CG + +C +P + VV
Sbjct 257 DWTSYVSTCCGFK-CKPVLVASCSAMPGSVVV 287
>sp|P0C6V2|R1A_CVPPU Replicase polyprotein 1a OS=Porcine transmissible
gastroenteritis coronavirus (strain Purdue) OX=11151
GN=1a PE=1 SV=1
Length=4017
Score = 2519 bits (6529), Expect = 0.0, Method: Composition-based stats.
Identities = 713/2281 (31%), Positives = 1117/2281 (49%), Gaps = 133/2281 (6%)
Query 2142 FNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAK--LCLDAGINYVKSPK 2199
F Y F ++ + + K K L V++
Sbjct 1821 FGRYADMFFMAGDKILRLLLEVFKYLLVLFMCLRSTKMPKVKVKPPLAFKDFGAKVRTLN 1880
Query 2200 FSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVTTMDFC 2259
+ + + L + + + CNG + Y NSS + + C
Sbjct 1881 YMRQLNKPSVWRYAKLVLLLIAIYNFFYLFVSIPVVHKLTCNGAVQAYKNSSFIKSA-VC 1939
Query 2260 EGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLG 2319
S C CL+ D L + L+ +K D L L+Y F F
Sbjct 1940 GNSILCKACLASYDELADFQHLQVTW----DFKSDPLWNRLVQ---LSYFAFLAVFG--- 1989
Query 2320 LSAIMQVFFGYFASHFISNSWLMWF-------IISIVQMAPVSAMVRMYIFFASFYYIWK 2372
+ ++ F YF S ++ N WL +F + +V +SA + + K
Sbjct 1990 -NNYVRCFLMYFVSQYL-NLWLSYFGYVEYSWFLHVVNFESISAEFVIVVIVVKAVLALK 2047
Query 2373 SYVHIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNC 2432
HI+ C++ +C C + R TR+ +VNG ++ YV+ANG FCK HN+ C NC
Sbjct 2048 ---HIVFACSNPSCKTCSRTARQTRIPIQVVVNGSMKTVYVHANGTGKFCKKHNFYCKNC 2104
Query 2433 DTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLY---------FD 2483
D++ +TFI DE+ RDLS K+ + TD+S V V +G Y +D
Sbjct 2105 DSYGFENTFICDEIVRDLSNSVKQTVYATDRSHQEVTKVECSDGFYRFYVGDEFTSYDYD 2164
Query 2484 KAGQKTYERHPLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCDESASKSASVYYSQLMC 2543
+K + L + LD+ + GS NV ++A VY+SQL+
Sbjct 2165 VKHKKYSSQEVLKSMLLLDDFIVYSPSGSALANV--------------RNACVYFSQLIG 2210
Query 2544 QPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSELAKGVAL 2603
+PI +++ L+ D+ S + +F+A + +F+V + + K L E + L
Sbjct 2211 KPIKIVNSDLLEDL--SVDFKGALFNAKKNVIKNSFNVDVSECKNL-----DECYRACNL 2263
Query 2604 DGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYNKV--ENMT 2661
+ STF A +H + +T S NNF + K ++
Sbjct 2264 NVSFSTFEMAVNN------------------AHRFGILITDRSFNNFWPSKVKPGSSGVS 2305
Query 2662 PRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNIPFRLTC 2721
D+G C+ +A+ +NA+V S++W +D+ +LS +K + + + F LT
Sbjct 2306 AMDIGKCMTSDAKIVNAKVLTQRGKSVVWLSQDFAALSSTAQKVLVKTFVEEGVNFSLTF 2365
Query 2722 ATTRQVVNVI----TTKISLKGGKIVSTCFKLMLKATLLCVLAALVCYIVMPVHTLSIHD 2777
++ T +S K G + + +L + +C + +
Sbjct 2366 NAVGSDDDLPYERFTESVSPKSGSGFFDVITQLKQIVILVFVFIFICGLCSVYSVATQSY 2425
Query 2778 GYTNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGSYKN-DKSCPVVAA-II 2835
+ E Y I++G+ + T C N + GF WF + G KSCP+V +
Sbjct 2426 IESAEGYDYMVIKNGIVQPFDDTISCVHNTYKGFGDWFKAKYGFIPTFGKSCPIVVGTVF 2485
Query 2836 TREIGFIVPGLPGTVLRAINGDFLHFLPRVFSAVGNICYTPSKLIEYSDFATSACVLAAE 2895
E +P +P V +I G L F V N+CY + D CV
Sbjct 2486 DLENMRPIPDVPAYV--SIVGRSLVFAINAAFGVTNMCYDHTGNAVSKDSYFDTCVFNTA 2543
Query 2896 CTIFKDAMGKPVPYCYDTNLLEGSISYSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTT 2955
CT G + YC L+EG+ YS+L PD Y G++++ P +R V T
Sbjct 2544 CTTLTGLGGT-IVYCAKQGLVEGAKLYSDLMPDYYYEHASGNMVKLPAIIRGLGLRFVKT 2602
Query 2956 FDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPV 3015
YCR G C S+ G C +V +NE +G CG + N+F +
Sbjct 2603 QATTYCRVGECIDSKAGFCFGGDNWFVYDNEF---GNGYICGNSVLGFFKNVFKLFNSNM 2659
Query 3016 GALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAY 3075
+ S +++ IIA L Y +KF+++FG+ ++ ++ L+ + V
Sbjct 2660 SVVATSGAMLVNIIIACLAIAMCYGVLKFKKIFGDCTFLIVM-IIVTLVVNNVSYFVTQN 2718
Query 3076 SFLPGVYSVFYLYLTFYFTNDVSFLAHLQ--WFAMFSPIVPFWITAIYVFCISLKHCHWF 3133
+F +Y++ Y ++ T +++ L + + + P+++ Y+
Sbjct 2719 TFFMIIYAIVY----YFITRKLAYPGILDAGFIIAYINMAPWYVITAYILVFLYDSLPSL 2774
Query 3134 FNNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYK 3192
F + +F G F FE AA+ TF+++ Y + + T + + Y +NKYK
Sbjct 2775 FKLKVSTN-LFEGDKFVGNFESAAMGTFVIDMRSYETIVNST--SIARIKSYANSFNKYK 2831
Query 3193 YFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGK 3252
Y++G++ YR A HL KAL D+S + D+LY PP S+ S LQSG RKMA PSG
Sbjct 2832 YYTGSMGEADYRMACYAHLGKALMDYSVNRTDMLYTPPTVSVNST-LQSGLRKMAQPSGL 2890
Query 3253 VEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAGN 3312
VE C+V+V+ G LNGLWL D V CPRHVI + + NYE+ + H+F V N
Sbjct 2891 VEPCIVRVSYGNNVLNGLWLGDEVICPRHVIASDTTRV-INYENEMSSVRLHNFSVSKNN 2949
Query 3313 VQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRP 3372
V L V+ + L LKV+ NP TP++KF I+ G++F++LACY G P VY MR
Sbjct 2950 VFLGVVSARYKGVNLVLKVNQVNPNTPEHKFKSIKAGESFNILACYEGCPGSVYGVNMRS 3009
Query 3373 NHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQ 3432
TIKGSF+ G+CGSVG+ ++ + F YMHH+EL G H G++ EG+ YG + D+ + Q
Sbjct 3010 QGTIKGSFIAGTCGSVGYVLENGILYFVYMHHLELGNGSHVGSNFEGEMYGGYEDQPSMQ 3069
Query 3433 AAGTDTTITLNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGP 3492
GT+ + NV+A+LYAA+ING+RWF+ + +L +N A ++ L+ D
Sbjct 3070 LEGTNVMSSDNVVAFLYAALINGERWFVTNTSMSLESYNTWAKTNSFTELSS--TDAFSM 3127
Query 3493 LSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQ-GKFKK 3551
L+A+TG +V + ++ L G GRTIL L DEFTP +V+RQ GV Q GK K
Sbjct 3128 LAAKTGQSVEKLLDSIVRL-NKGFGGRTILSYGSLCDEFTPTEVIRQMYGVNLQAGKVKS 3186
Query 3552 IVKGTHHWMLLTFLTSLLIL-VQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLL-VKHK 3609
+ ++T +T L ++ ++ F ++ F+ L + + + + +KHK
Sbjct 3187 FF-----YPIMTAMTILFAFWLEFFMYTPFTWINP-TFVSIVLAVTTLISTVFVSGIKHK 3240
Query 3610 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLL 3669
F F+LPS+ V N+ + S+ + + +E +T ++ ++ ++
Sbjct 3241 MLFFMSFVLPSVILVTAHNL-FWDFSYYESLQSIVENTNTMFLPVDMQGVMLTVFCFIVF 3299
Query 3670 ILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQA----------ISMWALVISVTS 3719
+ + R + + ++ + V D+ ++M +++S+T+
Sbjct 3300 VTYSVRFFTCKQSWFSLAVTTILVIFNMVKIFGTSDEPWTENQIAFCFVNMLTMIVSLTT 3359
Query 3720 NYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNR 3779
VV +A IV + ++CI +VY GY CCY+G+ +NR
Sbjct 3360 KDWMVVIASYRIAYYIVVCVM--PSAFVSDFGFMKCISIVYMACGYLFCCYYGILYWVNR 3417
Query 3780 YFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKM 3839
+ +T GVY + VS E +YM + L PK++ DA L+ KL+G+GGK IK++TVQSK+
Sbjct 3418 FTCMTCGVYQFTVSAAELKYMTANNLSAPKNAYDAMILSAKLIGVGGKRNIKISTVQSKL 3477
Query 3840 SDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQ 3899
+++KCT+VVLL +L ++ VES+SK W CV LHN+I L D EK+++L++ LS
Sbjct 3478 TEMKCTNVVLLGLLSKMHVESNSKEWNYCVGLHNEINLCDDPEIVLEKLLALIAFFLSKH 3537
Query 3900 GAVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVANGDSEVVLKKLKK 3959
D++ L E +N LQ++AS +++LPS+ A A+ E+A N S +LK+L K
Sbjct 3538 NTCDLSELIESYFENTTILQSVASAYAALPSWIALEKARADLEEAKKNDVSPQILKQLTK 3597
Query 3960 SLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDN 4019
+ N+AKS+F+R+A++Q+KL+KMA+QA MYK+AR+ D+++K+ SAM ++LF ML+KLD
Sbjct 3598 AFNIAKSDFEREASVQKKLDKMAEQAAASMYKEARAVDRKSKIVSAMHSLLFGMLKKLDM 3657
Query 4020 DALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVV 4079
++N II+ AR+G +PL+IIP +A +L+V+ P + N YA A+W I +V
Sbjct 3658 SSVNTIIDQARNGVLPLSIIPAASATRLVVITPSLEVFSKIRQENNVHYAGAIWTIVEVK 3717
Query 4080 DADSKIVQLSEINMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA 4139
DA+ V L E+ N NL WPL +T R KLQNNE+ P L++ + A T
Sbjct 3718 DANGSHVHLKEVTAANELNLTWPLSITCERT---TKLQNNEIMPGKLKERAVRASATLDG 3774
Query 4140 CTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKG 4199
+ A + G F+ A ++ +LK+ ++ + I ELE P RF D G
Sbjct 3775 EAFGSGKALMASESGKSFMYAFIASDNNLKYVKWESN--NDIIPIELEAPLRFYVDGANG 3832
Query 4200 PKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDPAKAYKD 4259
P+VKYLYF+K LN L RG VLG + ATVRLQAG TE P+NS++L+ CAF+ DPAKAY D
Sbjct 3833 PEVKYLYFVKNLNTLRRGAVLGYIGATVRLQAGKPTEHPSNSSLLTLCAFSPDPAKAYVD 3892
Query 4260 YLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGF 4319
+ G QP+ NCVKML G G A+T EAN Q+S+GGAS C+YCRCH++HP G
Sbjct 3893 AVKRGMQPVNNCVKMLSNGAGNGMAVTNGVEANTQQDSYGGASVCIYCRCHVEHPAIDGL 3952
Query 4320 CDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNR 4379
C KGK+VQIPT DP+ F + N VC VCG W GC CD R + ++LN
Sbjct 3953 CRYKGKFVQIPTG-TQDPIRFCIENEVCVVCGCWLNNGCMCD--RTSMQSFTVDQSYLNE 4009
Query 4380 V 4380
Sbjct 4010 C 4010
Score = 206 bits (525), Expect = 5e-51, Method: Composition-based stats.
Identities = 73/367 (20%), Positives = 117/367 (32%), Gaps = 32/367 (9%)
Query 1531 DKLKSLLSLREVKTIKVFTTVDNTNLHTQLVDMSMTYGQQF-GPTYLDGADVTKIKPHVN 1589
D+ + + +I V T DN N V TYG+Q G + DVT P
Sbjct 1475 DQERQTIENFFSCSIPVNVTEDNVNHERVSVSFDKTYGEQLKGTVVIKDKDVTNQLPSAF 1534
Query 1590 HEGKTFFVLPSDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADN 1649
G+ D F S Y K++ K DN
Sbjct 1535 DVGQKVIKAIDIDWQAHYGFRDAAAFSASSHDAY--------KFEVVTHSNFIVHKQTDN 1586
Query 1650 NCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETM 1709
NC+++++ LALQ+L+ ++ P ++ + F ++ S GE GD +
Sbjct 1587 NCWINAICLALQRLKPQWKFPGVRGLWNEFLERKTQGFVHMLYHISGVKKGEPGDAELML 1646
Query 1710 THLLQHANLESAKRVLN-VVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVSIPCVCGR 1768
L + + V + C C K G + G CV G
Sbjct 1647 HKLGDLMDNDCEIIVTHTTACDKCA-KVEKFVGPVVAAPLAIH-------GTDETCVHGV 1698
Query 1769 DATQYLVQQESSFVMMS--APPAEYKLQQGTFLCANEYTGNYQCGHYTHITAKETL---- 1822
+ Q + + + S P L+ ++C Y+G+ + GHYT+ + L
Sbjct 1699 SVNVKVTQIKGTVAITSLIGPIIGEVLEATGYIC---YSGSNRNGHYTYYDNRNGLVVDA 1755
Query 1823 ---YRIDGAHLTKMSEYKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKK 1879
Y + L + V K + K+ E KL
Sbjct 1756 EKAYHFNRDLLQVTTAIASNF--VVKKPQAEERPKNCAFNKVAASPKIVQEQKLLAIESG 1813
Query 1880 DNAYYTE 1886
N TE
Sbjct 1814 ANYALTE 1820
Score = 194 bits (492), Expect = 3e-47, Method: Composition-based stats.
Identities = 88/397 (22%), Positives = 140/397 (35%), Gaps = 53/397 (13%)
Query 875 VVAEAVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEENF--------SSRMYCSFY 926
+V E V L P+ + N G+ D V T G F +
Sbjct 1171 IVLERAVFKLTPLKESF-NYGVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVK 1229
Query 927 PPDEEEEDDAECEEEEIDETCEHEYGTED----------------DYQGLPLEFGASAET 970
P + + EH Y + + +
Sbjct 1230 PVMHAVYTGTTQNGHYMVDDIEHGYCVDGMGIKPLKKRCYTSTLFINANVMTRAEKPKQE 1289
Query 971 VRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQF--TGYLKLTDNVAIKCVDIVKEAQ 1028
+VE+ E++ +++ E E P ++ + F G L ++ ++
Sbjct 1290 FKVEKVEQQPIVEENKSSIEKEEIQSPKNDDLILPFYKAGKLSFYQGALDVLINFLE--- 1346
Query 1029 SANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL 1088
P VIVNAAN LKH GGVA A++ T G + + S DY+K N + G +
Sbjct 1347 ---PDVIVNAANGDLKHMGGVARAIDVFTGGKLTERSKDYLKKNKSIAPGNAVFFENVIE 1403
Query 1089 AKKCLHVVGPNLNAGEDIQLLKAAYENF-NSQDILLAPLLSAGIFGAKPLQSLQVCVQTV 1147
L+ VGP L Y+ + +L PL+S GIF + SLQ ++TV
Sbjct 1404 HLSVLNAVGPRNGDSRVEAKLCNVYKAIAKCEGKILTPLISVGIFNVRLETSLQCLLKTV 1463
Query 1148 RTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPP--NTEDSKTEEKSVVQKPVDVK 1205
ND+ L V Y D + +E P TED+ E+ V
Sbjct 1464 --------NDRGLN---VFVYTDQERQTIENFFSCSIPVNVTEDNVNHERVSVSFDKTYG 1512
Query 1206 PKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHD 1242
++K T + + K +TN+L D+ K+
Sbjct 1513 EQLKG------TVVIKDKDVTNQLPSAFDVGQKVIKA 1543
Score = 103 bits (257), Expect = 7e-20, Method: Composition-based stats.
Identities = 57/271 (21%), Positives = 93/271 (34%), Gaps = 24/271 (9%)
Query 1587 HVNHEGKTFFVLPSDDTLR-SEAFEYYHTLDESF----LGRYMSALNHTKKWKFPQVGGL 1641
E +T V T + E D + +K + G
Sbjct 1024 SSQEEVETVEVADITSTEEDVDIVEVSAKDDPWAAAVDVQEAEQFNPSLPPFKTTNLNGK 1083
Query 1642 TSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGE 1701
+K DNNC++++ LQ + FN EA+ + + GD +F L A + G
Sbjct 1084 IILKQGDNNCWINACCYQLQAFDF-FN----NEAWEKFKKGDVMDFVNLCYAATTLARGH 1138
Query 1702 LGDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNLKTGVS 1761
GD + +L + +AK VL C CG+K +E ++ T ++ GV
Sbjct 1139 SGDAEYLLELMLN--DYSTAKIVLAAKCG-CGEKEIV---LERAVFKLTPLKESFNYGVC 1192
Query 1762 IPCVCGRDATQYLVQQESSFV---MMSAPPAEYKLQQGTFLCANEYTGNYQCGHYTHITA 1818
C+ V+ FV + P + + YTG Q GHY
Sbjct 1193 GDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHA--VYTGTTQNGHYMVDDI 1250
Query 1819 KETLYRIDGAHLTKMSEYKGPVTDVFYKETS 1849
+ Y +DG + K T + +
Sbjct 1251 EHG-YCVDGMGIKP--LKKRCYTSTLFINAN 1278
Score = 70.1 bits (170), Expect = 1e-09, Method: Composition-based stats.
Identities = 74/378 (20%), Positives = 119/378 (31%), Gaps = 56/378 (15%)
Query 185 YVDNNFCGPDGYPLDCIKDFLARAGKSMCTLSEQLDYIESKRGVYCCRDHEHEIAWFTER 244
YVD CG DG P+ + DY + E+ AW T R
Sbjct 113 YVDQYMCGADGKPV---------------IEGDFKDYFG-DEDIIEFEGEEYHCAWTTVR 156
Query 245 SDKSYEHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVY 304
+K QT F I+ + + P N + + P V+K + +Y
Sbjct 157 DEKPLNQQTLFTIQEIQYNLDIPHKLP------NCATRHVAPPVKKNSKIVLSEDYKKLY 210
Query 305 PVASPQECNNMHLSTLMKCNHCDEVSWQTCDFLKATC-EHCGTENLVIEGPTTCGYLPTN 363
+ S M C + T F+ AT CG+E+ + T
Sbjct 211 DIFG---------SPFMGNGDCLSKCFDTLHFIAATLRCPCGSESSGVGDWTG------- 254
Query 364 AVVKMPCPACQDPEIGPEHSVADYHNHSNIETRLRKGGRTRCFGGCVFAYVGCYNKRAYW 423
K C G ++ D + T + G + F CV Y G + W
Sbjct 255 --FKTACCGLSGKVKGV--TLGDIKPGDAVVTSMSAGKGVKFFANCVLQYAGDVEGVSIW 310
Query 424 -VPRASADIGSGHT-GITGDNVETLNEDLLEILSRERVNINIVGDFHLNEEVAIILASFS 481
V + + T G G+ + + + +++ I GD II
Sbjct 311 KVIKTFTVDETVCTPGFEGELNDFIKPESKSLVACSVKRAFITGDIDDAVHDCIITGKLD 370
Query 482 ASTSAFIDTIKSLDYKSFKTIVESCGNYKVTKGKPVKGAWNIGQQRSVLTPLCGFPSQAA 541
ST+ F + L +K V+ CG V AW + ++ + L Q
Sbjct 371 LSTNLFGNV--GLLFKKTPWFVQKCGALFV-------DAWKVVEE--LCGSLTLTYKQIY 419
Query 542 GVIRSIFARTLDAANHSI 559
V+ S+ N+
Sbjct 420 EVVASLCTSAFTIVNYKP 437
Score = 53.1 bits (126), Expect = 1e-04, Method: Composition-based stats.
Identities = 126/755 (17%), Positives = 216/755 (29%), Gaps = 113/755 (15%)
Query 659 IVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNL-GEVFIAQSKGLY 717
++ ++V D K NK + + I G + FI + +Y
Sbjct 737 LIGNGVKVVCDGCKGFANQLSKGYNKLCNAARNDIEIGGIPFSTFKTPTNTFIEMTDAIY 796
Query 718 RQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGA 777
+GK L D + + E + +
Sbjct 797 SVIEQGKA----------------LSFRDADVPVVDNGTISTADWSEPILLEPAEYVKPK 840
Query 778 IVGTPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDT-VWEVQG 836
G + + G + +D+ Y G K G K V+F E+ V E+
Sbjct 841 NNGNVIVIAGYTFYKDEDEHFYPY---GFGKIVQRMYNKMGGGDKTVSFSEEVDVQEIAP 897
Query 837 YKNVRITFELD-ERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSDLLTNMG 895
V++ FE D E V VL +GT E++ + L + D L N G
Sbjct 898 VTRVKLEFEFDNEIVTGVLERAIGTRYKFTGTT----WEEFEESISEELDAIFDTLANQG 953
Query 896 IDLDE-WSVATFYLFD-DAGEENFSSRMYCSFYPP-------------DEEEEDDAECEE 940
++L+ + T FD + S+ + E E+D E E
Sbjct 954 VELEGYFIYDTCGGFDIKNPDGIMISQYDINITADEKSEVSASSEEEEVESVEEDPENEI 1013
Query 941 EEIDETCEHEYGTEDDYQGLPLEFGASAETV-RVEEEEEEDWLDDTTEQSEIEPEPEPTP 999
E E E E+ + ++ E V VE ++D + E E P
Sbjct 1014 VEASEGAEGTSSQEEVETVEVADITSTEEDVDIVEVSAKDDPWAAAVDVQEAEQFNPSLP 1073
Query 1000 EEPVNQFTGYLKLT--DNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKAT 1057
G + L DN + N A K G +
Sbjct 1074 PFKTTNLNGKIILKQGDNNCWINACCYQLQA---FDFFNNEAWEKFKKGDVMDFVNLCYA 1130
Query 1058 NGAMQK------------ESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNA--- 1102
+ + +DY L C L + + P +
Sbjct 1131 ATTLARGHSGDAEYLLELMLNDYSTAKIVLAAKCGCGEKEIVLERAVFKLT-PLKESFNY 1189
Query 1103 ---GEDIQLLKAAYENFNSQDILLAPLLSA----GIFGAKPLQSLQVCVQT------VRT 1149
G+ +Q+ + + + + +LS +F KP+ T V
Sbjct 1190 GVCGDCMQVNTCRFLSVEGSGVFVHDILSKQTPEAMFVVKPVMHAVYTGTTQNGHYMVDD 1249
Query 1150 QVYIAVND----KALYEQVVMDYL---DNLKPRVEAPKQE--------EPPNTEDSKTEE 1194
+ D K L ++ L N+ R E PKQE +P E+ + E
Sbjct 1250 IEHGYCVDGMGIKPLKKRCYTSTLFINANVMTRAEKPKQEFKVEKVEQQPIVEENKSSIE 1309
Query 1195 KSVVQKPVDVKPKI-----------KACIDEVTTTLEETKFL---TNKLLLFADINGKLY 1240
K +Q P + + + +D + LE + L + +
Sbjct 1310 KEEIQSPKNDDLILPFYKAGKLSFYQGALDVLINFLEPDVIVNAANGDLKHMGGVARAID 1369
Query 1241 HDSQNMLRGEDMSFLEKDAPYMVG------DVITSGDITCVVIPSKKAGGTTEMLSRALK 1294
+ L +L+K+ G +VI + V P L K
Sbjct 1370 VFTGGKLTERSKDYLKKNKSIAPGNAVFFENVIEHLSVLNAVGPRNGDSRVEAKLCNVYK 1429
Query 1295 KVPV--DEYITTYPGQGCAGYTLEEAKTALKKCKS 1327
+ + +T G LE + L K +
Sbjct 1430 AIAKCEGKILTPLISVGIFNVRLETSLQCLLKTVN 1464
>sp|P0C6V5|R1A_IBVM Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain M41) OX=11127 GN=1a PE=1 SV=1
Length=3953
Score = 2509 bits (6502), Expect = 0.0, Method: Composition-based stats.
Identities = 857/2952 (29%), Positives = 1347/2952 (46%), Gaps = 295/2952 (10%)
Query 1540 REVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLP 1599
K ++ T D + ++ + G QFG + V + E K +P
Sbjct 1175 ATCKQKTIYLTEDGVKYRSVVLKPGDSLG-QFGQVFARNKVVFSA---DDVEDKEILFIP 1230
Query 1600 SDDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLA 1659
+ D E Y+ LD Y+ L +KW ++W D NC++SS ++
Sbjct 1231 TTDKTILE----YYGLDAQKYVTYLQTL--AQKWDVQYRDNFVILEWRDGNCWISSAIVL 1284
Query 1660 LQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLE 1719
LQ +++F L EA+ + GD +F A A N VG+ D + +L +H + +
Sbjct 1285 LQAAKIRFKG-FLAEAWAKLLGGDPTDFVAWCYASCNAKVGDFSDANWLLANLAEHFDAD 1343
Query 1720 SAKRVL-NVVCKHCGQKTTTLTGVEAVM-YMGTLSYDNLKTGVSIPCVCGRDATQYLVQQ 1777
+L V +CG K+ L G+EA + + + + KT S CG +T +++
Sbjct 1344 YTNALLKKCVSCNCGVKSYELRGLEACIQPVRAPNLLHFKTQYSNCPTCGASSTDEVIEA 1403
Query 1778 ESSFVMMSAPPAEYKLQ-QGTFLCANEYTGNYQCGH-YTHITAKETLYRIDGAHLTKMSE 1835
++++ A + + + G+ GH YT K D +
Sbjct 1404 SLPYLLLFATDGPATVDCDENAVGTVVFIGSTNSGHCYTQADGKA----FDNLAKDRKFG 1459
Query 1836 YKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQ 1895
K P Y S + P L + K A ++ + + T
Sbjct 1460 RKSPYITAMYTRFSLRSE----------------NPLLVVEHSKGKAKVVKEDVSNLATS 1503
Query 1896 PLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSAS 1955
ASFD+ D Q + L V PD + Y +
Sbjct 1504 SK--ASFDDL----------TDFEQW--YDSNIYESLKVQETPD--------NLDEYVSF 1541
Query 1956 FKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDN 2015
T + + P T +R + S + + F DT
Sbjct 1542 ------------------TTKEDSKLPLTLKVRGIKSVVDFRSKDGFTYKLTPDTD---- 1579
Query 2016 LACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
S+ P V+++ +++ +E VVG+ + E +
Sbjct 1580 --ENSKTPVYYPVLDSISLRAIWVEGSAN--FVVGHPNYYSKSLRIPTFWENAESFVKMG 1635
Query 2076 Y-VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQAAITTSNCA 2134
Y ++ ++ + + L+ + A ++ S ++ Q A
Sbjct 1636 YKIDGVTMGLWRAEHLNK----PNLERIFNIAKKAIVGSSVVT------TQCGKILVKAA 1685
Query 2135 KRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKLCLDAGINY 2194
+A +V + + + + LC FT+ + + K V + +
Sbjct 1686 TYVADKVGDGVVRNITDRIKGLCGFTRGHFEK---KMSLQFLKTLVFFFFYFLKASSKSL 1742
Query 2195 VKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRELYLNSSNVT 2254
V S K + LL++ S V VL S C + +S +V
Sbjct 1743 VSSYKIVLCKVVFATLLIVWFIYTSNPVVFTGIRVL-DFLFEGSLCGPYNDYGKDSFDV- 1800
Query 2255 TMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKF 2314
+ +C G F C +CL DSL Y +++ YK + G+ W Y++F
Sbjct 1801 -LRYCAGDFTCRVCLHDRDSLHLYKHAYSVE---QIYKDAAS--GINFNWNWLYLVFLIL 1854
Query 2315 F-----YLLGLSAIMQVFFGYFASHFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYY 2369
F + + ++ +L WF V + + F + +Y
Sbjct 1855 FVKPVAGFVIICYCVKYLVLSSTVLQTGVGFLDWF---------VKTVFTHFNFMGAGFY 1905
Query 2370 IWKSYV-----HIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYVYANGGRGFCKT 2424
W Y H + C TC +C + R+ R E + +V G K+ +VY N G FCK
Sbjct 1906 FWLFYKIYVQVHHILYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHVYTNSGYNFCKR 1965
Query 2425 HNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAVKNGALHLYFDK 2484
HNW C NCD + +TF+S EVA +LS + KR + PT + ++V V + ++L +
Sbjct 1966 HNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKPTAYAYHVVYEACVVDDFVNLKYKA 2025
Query 2485 A-GQKTYERHPLSHFVNLDNL-RANNTKGSLPINVIVFDGKSKCDESA------SKSASV 2536
A K + F D L +A K +L I DG C+ + +K+A+V
Sbjct 2026 AIPGKDNASSAVKCFSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSAHALEEAKNAAV 2085
Query 2537 YYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEKLKALVATAHSE 2596
YY+Q +C+PIL+LDQAL + VS + D S SV TA
Sbjct 2086 YYAQYLCKPILILDQALYEQL-IVEPVSKSVIDKVCSILSNIISVD---------TAALN 2135
Query 2597 LAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGDSCNNFMLTYN- 2655
G D +LS ++ ++ H+ ++E TGD N + +Y
Sbjct 2136 YKAGTLRDALLSI-------------TKDEEAVDMAIFCHNHEVEYTGDGFTNVIPSYGM 2182
Query 2656 KVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRKQIRSAAKKNNI 2715
+ +TPRD G I+ +A N +V + ++W D + LS+ K + SA K+
Sbjct 2183 DTDKLTPRDRGFLINADASIANLRVKNAP--PVVWKFSDLIKLSDSCLKYLISATVKSGG 2240
Query 2716 PFRLTCATTRQVVNVITTKISL--KGGKIVSTCFKL------MLKATLLCVLAALVCYIV 2767
F +T + +QV++ T K+ + K G +++ FK L + A + Y
Sbjct 2241 RFFITKSGAKQVISCHTQKLLVEKKAGGVINNTFKWFMSCFKWLFVFYILFTACCLGYYY 2300
Query 2768 MPVHTLSIHDGY----TNEIIGYKAIQDGVTRDIISTDDCFANKHAGFDAWFSQRGGSYK 2823
M ++ +H Y T + G+K I GV R+I+S D+CF+NK FDA++ G SY+
Sbjct 2301 MEMNKSFVHPMYDVNSTLHVEGFKVIDKGVIREIVSEDNCFSNKFVNFDAFW---GKSYE 2357
Query 2824 NDKSCPVVAAIITREIGFIVPGLPGTVLRAING-DFLH---------FLPRVFSAVGNIC 2873
N+K+CP+V +I + G + G+PG V ++G F+H ++P F+ +
Sbjct 2358 NNKNCPIVTVVIDGD-GTVAVGVPGFVSWVMDGVMFVHMTQTDRRPWYIPTWFNRE-IVG 2415
Query 2874 YTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD-TNLLEGSISYSELRPDTRYV 2932
YT +I F TS + +A C ++ A P YC++ N G++ + + P Y
Sbjct 2416 YTQDSIITEGSFYTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALPFGSIIPHRVYF 2474
Query 2933 LMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRWVLNNEHYRALS 2992
+G + P L + +V YCR CE ++ G C+S +WVL N+ Y +
Sbjct 2475 QPNGVRLIVPQQILH-TPYIVKFVSDSYCRGSVCEYTKPGYCVSLDSQWVLFNDEYISKP 2533
Query 2993 GVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYN 3052
GVFCG L+ N+ + V ++ + +I +++ +KF+ VF Y
Sbjct 2534 GVFCGSTVRELMFNMVSTFFTGVNP-NIYIQLATMFLILVVIVLIFAMVIKFQGVFKAYA 2592
Query 3053 HVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPI 3112
+V L+++++ +LC+ S L + V Y Y + + + + + H F I
Sbjct 2593 TIVFTIMLVWVINAFVLCVHSYNSVLAVILLVLYCYASMVTSRNTAIIMHCWLVFTFGLI 2652
Query 3113 VPFWITAIYVFCISLKH---CHWFFNNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMYL 3168
VP W+ Y+ I + W + R +++G F ++ AA TF++ ++
Sbjct 2653 VPTWLACCYLGFILYMYTPLVFWCYGTTKNTRKLYDGNEFVGNYDLAAKSTFVIRGTEFV 2712
Query 3169 KLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQ 3228
KL +E ++ YL+ Y + KY+SG Y +A LA AL+ + NSG +V+Y
Sbjct 2713 KLTNEIG---DKFEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQYRNSGVEVVYT 2769
Query 3229 PPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVYCPRHVICTAED 3288
PP+ SI + LQ+GF+K+ PS VE C+V V+ LNGLWL D++YCPRHV+
Sbjct 2770 PPRYSIGVSRLQAGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDSIYCPRHVL---GK 2826
Query 3289 MLNPNYEDLLIRKSNHSFLVQAGN-VQLRVIGHSMQNCLLRLKVDTSNPKTPKYKFVRIQ 3347
+ D+L +NH F V N V L V+ ++ +L L+ +N +TPKYKFV+
Sbjct 2827 FSGDQWGDVLNLANNHEFEVVTQNGVTLNVVSRRLKGAVLILQTAVANAETPKYKFVKAN 2886
Query 3348 PGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMEL 3407
G +F++ Y G+ G+Y MR N TI+ SFL G+CGSVGFNI+ V+F YMHH+EL
Sbjct 2887 CGDSFTIACSYGGTVIGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGVVNFFYMHHLEL 2946
Query 3408 PTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVI-------NGDRWFL 3460
P +H GTDL G+FYG +VD + AQ D +T N++AWLYAA+I + +W L
Sbjct 2947 PNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVKESSFSQPKW-L 3005
Query 3461 NRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRT 3520
T ++ D+N A + P + + LSA TG+ V + + +
Sbjct 3006 ESTTVSIEDYNRWASDNGFTPFSTST--AITKLSAITGVDVCKLLRTIM-VKSAQWGSDP 3062
Query 3521 ILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWM-----LLTFLTSLLILVQST 3575
ILG EDE TP V Q GV Q F V+ W L FL L +V T
Sbjct 3063 ILGQYNFEDELTPESVFNQVGGVRLQSSF---VRKATSWFWSRCVLACFLFVLCAIVLFT 3119
Query 3576 QWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLAT------------ 3623
L F+V+ L +MA+ + VKH A++ FLLP+L T
Sbjct 3120 AVPLKFYVHAAVIL-----LMAVLFIS-FTVKHVMAYMDTFLLPTLITVIIGVCAEVPFI 3173
Query 3624 --------VAYFNMVYMPASWVMRIMTWLELADTSLSGYR-LKDCVMYASALVLLILMTA 3674
V + + Y P + ++ W+ L + ++ ++ C M + LL+L
Sbjct 3174 YNTLISQVVIFLSQWYDPVVF-DTMVPWMLLPLVLYTAFKCVQGCYMNSFNTSLLMLYQ- 3231
Query 3675 RTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARA 3734
+ ++T N +T + GN W L + + L
Sbjct 3232 ---FMKLGFVIYTSSNTLTAYTE---GN--------WELFFELVHTIVLANVSSNSLIGL 3277
Query 3735 IVFVCVE----YYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDY 3790
IVF C + Y + L +M+ +G+ C CYFGL+ +N+ F LTLG Y++
Sbjct 3278 IVFKCAKWMLYYCNATYFNNYVLMAVMV--NGIGWLCTCYFGLYWWVNKVFGLTLGKYNF 3335
Query 3791 LVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMSDVKCTSVVLL 3850
VS ++RYM + PPK+ + F NI + GIGG + +ATVQSK+SDVKCT+VVL+
Sbjct 3336 KVSVDQYRYMCLHKVNPPKTVWEVFTTNILIQGIGGDRVLPIATVQSKLSDVKCTTVVLM 3395
Query 3851 SVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINRLCEE 3910
+L +L VE++SK+ A V+LHN IL + D E + ++ +L L + +D+ C++
Sbjct 3396 QLLTKLNVEANSKMHAYLVELHNKILASDDVGECMDNLLGMLITLFCIDSTIDLGEYCDD 3455
Query 3911 MLDNRATLQAIASEFSSLPSYAAYATAQEAYEQAVAN----GDSEVVLKKLKKSLNVAKS 3966
+L LQ++ EFS +PSYA Y A+ YE+ +A+ G ++ L +K+ N+AKS
Sbjct 3456 ILKRSTVLQSVTQEFSHIPSYAEYERAKSIYEKVLADSKNGGVTQQELAAYRKAANIAKS 3515
Query 3967 EFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNII 4026
FDRD A+Q+KL+ MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K+D++ LN +
Sbjct 3516 VFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKKIDSEKLNVLF 3575
Query 4027 NNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQQVVDADSKIV 4086
+ A G VPL +P+ + KL +V+PD T+ +G TY++ +W I V DAD +
Sbjct 3576 DQANSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNIDCVTDADGTEL 3635
Query 4087 QLSEINMD-----NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQMSCAAGTTQT 4138
+ + N+AWPL V R V LQNNEL P ++ +C AG Q
Sbjct 3636 HPTSTGSGLTYCISGDNIAWPLKVNLTRNGHNKVDVALQNNELMPHGVKTKACVAGVDQA 3695
Query 4139 ACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPK 4198
C+ ++ YY + G V A+ S + +LK A F G IY +L+PPC+F
Sbjct 3696 HCSVES-KCYYTSISGSSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDPPCKFGMKVGD 3753
Query 4199 GPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFCAFAVDPAKAY 4257
+V YLYFIK ++ RGMVLG+++ V LQ+ G+ TE +LS C+FAVDPA Y
Sbjct 3754 KVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLCSFAVDPADTY 3813
Query 4258 KDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHP--- 4314
Y+A+G QP+ NCVKML H G+G AIT P DQ+S+GGAS CLYCR HI HP
Sbjct 3814 CKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYCRAHIAHPGGA 3873
Query 4315 -NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQLREP------- 4366
N G C KG +VQIPTT DPVGF LRN VCTVC W GYGC CD LR+P
Sbjct 3874 GNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSLRQPKPSVQSV 3932
Query 4367 LMQSADASTFLN 4378
+ S +LN
Sbjct 3933 AVASGFDKNYLN 3944
Score = 209 bits (531), Expect = 1e-51, Method: Composition-based stats.
Identities = 84/353 (24%), Positives = 136/353 (39%), Gaps = 49/353 (14%)
Query 878 EAVVKTL-QPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDA 936
E VK L Q V D+L + G +D A L S + F + + A
Sbjct 870 EGAVKALPQKVIDVLGDWGEAVD----AQEQLCQQESTRVISEKSVEGFTGSCDAMAEQA 925
Query 937 ECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEE-------EEEDWLDDTTEQS 989
EE+EI E ++D P + ET +E +E+ + E+
Sbjct 926 IVEEQEIVPVVEQ---SQDVVVFTPADLEVVKETAEEVDEFILISAVPKEEVVSQEKEEP 982
Query 990 EIEPEPEPTPEEPVN----------------QFTGYLKLTDNVAIKCVDIVKEAQSANPM 1033
++E EP + +F Y ++A+ I K
Sbjct 983 QVEQEPTLVVKAQREKKAKKFKVKPATCEKPKFLEYKTCVGDLAVV---IAKALDEFKEF 1039
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCL 1093
IVNAAN H+ HGGGVA A+ + DY+K +GP + +C+
Sbjct 1040 CIVNAANEHMSHGGGVAKAIADFCGPDFVEYCADYVKKHGPQQ---KLVTPSFVKGIQCV 1096
Query 1094 -HVVGPNLNAGEDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPLQSLQVCVQTVRTQ 1150
+VVGP + L AAY++ ++ + P+LS+GIFG ++ + +R
Sbjct 1097 NNVVGPRHGDSNLREKLVAAYKSVLVGGVVNYVVPVLSSGIFGVD----FKISIDAMRE- 1151
Query 1151 VYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVD 1203
+ + L + +++D KQ+ TED + +SVV KP D
Sbjct 1152 AFKGCAIRVLLFSLSQEHIDYFDATC---KQKTIYLTEDG-VKYRSVVLKPGD 1200
Score = 43.5 bits (101), Expect = 0.12, Method: Composition-based stats.
Identities = 95/572 (17%), Positives = 161/572 (28%), Gaps = 89/572 (16%)
Query 786 NGLMLLEIKDKEQYCALSPGLLATNNVFRLKGGAPIKGVTFGEDTVWEV--QGYKNVRIT 843
N + KD+ Y L A N V + G K VTFGE TV E+ ++++
Sbjct 643 NYMFFRFKKDENIYYTPMSQLGAINVVCKAGG----KTVTFGETTVQEIPPPDVVFIKVS 698
Query 844 FELD-ERVDKVLNEKCSV-YTVESGTEVTEFACVVAEAVVKTLQPV-----------SDL 890
E E + + + VE+ V + VV E + L+ L
Sbjct 699 IECCGEPWNTIFKKAYKEPIEVETDLTVEQLLSVVYEKMCDDLKLFPEAPEPPPFENVTL 758
Query 891 LTNMGIDLDEWSVATF-YLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEH 949
+ G DLD Y ++ ++ + EE D E EE DE +
Sbjct 759 VDKNGKDLDCIKSCHLIYRDYESDDDIEEEDAEECDTDSGDAEECDTNLECEEEDEDTKV 818
Query 950 EYGTED---DYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQF 1006
+D + LPL+ S + ++ D ++
Sbjct 819 LALIQDPASNKYPLPLDDDYSVYNGCIVHKDALDVVN----------------------- 855
Query 1007 TGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESD 1066
L + + ++ VI + G A A Q+ES
Sbjct 856 ---LPSGEETFVVNNCFEGAVKALPQKVI------DVLGDWGEA---VDAQEQLCQQEST 903
Query 1067 DYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQL-----LKAAYENFNSQDI 1121
I GSC + +V P + +D+ + L+ E D
Sbjct 904 RVISEKSVEGFTGSCDAMAEQAIVEEQEIV-PVVEQSQDVVVFTPADLEVVKETAEEVDE 962
Query 1122 LLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQ 1181
+ L+SA + V + ++ V K P
Sbjct 963 FI--LISA----VPKE-------EVVSQEKEEPQVEQEPTLVVKAQREKKAKKFKVKPAT 1009
Query 1182 EEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYH 1241
E P + KT + + K + + + +
Sbjct 1010 CEKPKFLEYKTCVGDLAVVIAKALDEFK---EFCIVNAANEH-----MSHGGGVAKAIAD 1061
Query 1242 DSQNMLRGEDMSFLEKDAPYM--VGDVITSGD--ITCVVIPSKKAGGTTEMLSRALKKVP 1297
+++K P V G + VV P E L A K V
Sbjct 1062 FCGPDFVEYCADYVKKHGPQQKLVTPSFVKGIQCVNNVVGPRHGDSNLREKLVAAYKSVL 1121
Query 1298 VDEYITTYPGQGCAGYTLEEAKTALKKCKSAF 1329
V + +G + K ++ + AF
Sbjct 1122 VGGVVNYVVPVLSSGIFGVDFKISIDAMREAF 1153
>sp|P0C6V4|R1A_IBVBC Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette CK) OX=160235 GN=1a PE=3
SV=1
Length=3951
Score = 2487 bits (6446), Expect = 0.0, Method: Composition-based stats.
Identities = 852/2962 (29%), Positives = 1326/2962 (45%), Gaps = 317/2962 (11%)
Query 1541 EVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPS 1600
K ++ T D + ++ + G QFG Y V + E K +P+
Sbjct 1174 TCKQKTIYLTEDGVKYRSIVLKPGDSLG-QFGQVYAKNKIVFTA---DDVEDKEILYVPT 1229
Query 1601 DDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLAL 1660
D E Y+ LD Y+ L +KW ++W D NC++SS ++ L
Sbjct 1230 TDKSILE----YYGLDAQKYVIYLQTL--AQKWNVQYRDNFLILEWRDGNCWISSAIVLL 1283
Query 1661 QQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLES 1720
Q +++F L EA+ + GD +F A A VG+ D + +L +H + +
Sbjct 1284 QAAKIRFKG-FLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFSDANWLLANLAEHFDADY 1342
Query 1721 AKRVLNV-VCKHCGQKTTTLTGVEAVM-YMGTLSYDNLKTGVSIPCVCGRDATQYLVQQE 1778
L V +CG K+ L G+EA + + + + KT S CG + T +++
Sbjct 1343 TNAFLKKRVSCNCGIKSYELRGLEACIQPVRATNLLHFKTQYSNCPTCGANNTDEVIEAS 1402
Query 1779 SSFVMMSAP--PAEYKLQQGTFLCANEYTGNYQCGH-YTHITAKETLYRIDGAHLTKMSE 1835
++++ A PA + + + G+ GH YT D +
Sbjct 1403 LPYLLLFATDGPATVDCDEDA-VGTVVFVGSTNSGHCYTQAAG----QAFDNLAKDRKFG 1457
Query 1836 YKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQ 1895
K P Y ++ K ++ +
Sbjct 1458 KKSPYITAMYTRFAFKNETSLPVAKQSKGKSKSVKEDVSNL------------------A 1499
Query 1896 PLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSAS 1955
ASFDN D Q + L V PD ++ Y +
Sbjct 1500 TSSKASFDNL----------TDFEQW--YDSNIYESLKVQESPD--------NFDKYVSF 1539
Query 1956 FKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDN 2015
T + + P T +R + S + + F DT
Sbjct 1540 ------------------TTKEDSKLPLTLKVRGIKSVVDFRSKDGFIYKLTPDTD---- 1577
Query 2016 LACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
S+ P V++ + +K V GN ++ L
Sbjct 1578 --ENSKAPVYYPVLDAIS---------LKAIWVEGNANFVVGHPNY-YSKSLHIPTFWEN 1625
Query 2076 Y---------VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQA 2126
+ ++ + + L+ IA V S + +G+A
Sbjct 1626 AENFVKMGDKIGGVTMGLWRAEHLNKP---NLERIFNIAKKAIVGSSVVTTQCGKLIGKA 1682
Query 2127 AITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKL 2186
A ++ R + + + + F + + + K + +
Sbjct 1683 ATFIADKVGGGVVRNITDSIKGLCGITRG--HFERKMSPQF--------LKTLMFFLFYF 1732
Query 2187 CLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVREL 2246
+ + V S K + LL++ S + VL S C ++
Sbjct 1733 LKASVKSVVASYKTVLCKVVLATLLIVWFVYTSNPVMFTGIRVL-DFLFEGSLCGPYKDY 1791
Query 2247 YLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVL 2306
+S +V + +C F C +CL DSL Y +++ YK + G W
Sbjct 1792 GKDSFDV--LRYCADDFICRVCLHDKDSLHLYKHAYSVE---QVYKDAAS--GFIFNWNW 1844
Query 2307 AYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--------WLMWFIISIVQMAPVSAMV 2358
Y++F F V Y + + NS +L WF V +
Sbjct 1845 LYLVFLILFVKPVAGF---VIICYCVKYLVLNSTVLQTGVCFLDWF---------VQTVF 1892
Query 2359 RMYIFFASFYYIWKSYV-----HIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYV 2413
+ F + +Y W Y H + C TC +C + R+ R E + +V G K+ +V
Sbjct 1893 SHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHV 1952
Query 2414 YANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAV 2473
Y N G FCK HNW C NCD + +TF+S EVA +LS + KR + PT + ++VD +
Sbjct 1953 YTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKPTAYAYHVVDEACL 2012
Query 2474 KNGALHLYFD-KAGQKTYERHPLSHFVNLDNL-RANNTKGSLPINVIVFDGKSKCDESA- 2530
+ ++L + K + F D L +A K +L I DG C+ +
Sbjct 2013 VDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSA 2072
Query 2531 -----SKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEK 2585
+K+A++YY+Q +C+PIL+LDQAL + VS + D S+ SV
Sbjct 2073 HALEEAKNAAIYYAQYLCKPILILDQALYEQL-VVEPVSKSVIDKVCSILSSIISVD--- 2128
Query 2586 LKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGD 2645
TA G D +LS ++ ++ H+ D++ TGD
Sbjct 2129 ------TAALNYKAGTLRDALLSI-------------TKDEEAVDMAIFCHNHDVDYTGD 2169
Query 2646 SCNNFMLTY-NKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRK 2704
N + +Y +TPRD G I+ +A N +V + ++W + + LS+ K
Sbjct 2170 GFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAP--PVVWKFSELIKLSDSCLK 2227
Query 2705 QIRSAAKKNNIPFRLTCATTRQVVNVITTKISL--KGGKIVS---TCFKLMLKATLLCVL 2759
+ SA K+ + F +T + +QV+ T K+ + K G IVS CFK K L+ +
Sbjct 2228 YLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKCFKSYFKWLLIFYI 2287
Query 2760 AALVC---YIVMPVHTLSIHDGY----TNEIIGYKAIQDGVTRDIISTDDCFANKHAGFD 2812
C Y M V +H Y T + G+K I GV R+I+ D CF+NK FD
Sbjct 2288 LFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVPEDTCFSNKFVNFD 2347
Query 2813 AWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAING-DFLH---------FL 2862
A++ G Y N ++CP+V A+I + G + G+PG V ++G F+H ++
Sbjct 2348 AFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMFIHMTQTERKPWYI 2403
Query 2863 PRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD-TNLLEGSIS 2921
P F+ + YT +I F TS + +A C ++ A P YC++ N G++
Sbjct 2404 PTWFNRE-IVGYTQDSIITEGSFYTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALP 2461
Query 2922 YSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRW 2981
+ + P Y +G + P L + VV YCR CE + G C+S + +W
Sbjct 2462 FGSIIPHRVYFQPNGVRLIVPQQILH-TPYVVKFVSDSYCRGSVCEYTRPGYCVSLNPQW 2520
Query 2982 VLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYF 3041
VL N+ Y + GVFCG L+ ++ + V ++ + +I ++V
Sbjct 2521 VLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLATMFLILVVVVLIFAMV 2579
Query 3042 MKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLA 3101
+KF+ VF Y V L+++++ ILC+ S L + V Y Y + + + +
Sbjct 2580 IKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLYCYASLVTSRNTVIIM 2639
Query 3102 HLQWFAMFSPIVPFWITAIYVFCISLKH---CHWFFNNYLRKRVMFNGVTF-STFEEAAL 3157
H F IVP W+ Y+ I + W + R +++G F ++ AA
Sbjct 2640 HCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKLYDGNEFVGNYDLAAK 2699
Query 3158 CTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALND 3217
TF++ ++KL +E ++ YL+ Y + KY+SG Y +A LA AL+
Sbjct 2700 STFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQ 2756
Query 3218 FSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVY 3277
+ NSG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+ LNGLWL DT+Y
Sbjct 2757 YRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIY 2816
Query 3278 CPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAG-NVQLRVIGHSMQNCLLRLKVDTSNP 3336
CPRHV+ + D+L +NH F V V L V+ ++ +L L+ +N
Sbjct 2817 CPRHVL---GKFSGDQWNDVLNLANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANA 2873
Query 3337 KTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDC 3396
+TPKYKF++ G +F++ Y G+ G+Y MR N TI+ SFL G+CGSVGFNI+
Sbjct 2874 ETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGV 2933
Query 3397 VSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGD 3456
V+F YMHH+ELP +H GTDL G+FYG +VD + AQ D +T N++AWLYAA+I+
Sbjct 2934 VNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVK 2993
Query 3457 RW------FLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
+L T +++D+N A + P + + LSA TG+ V + +
Sbjct 2994 ESSFSLPKWLESTTVSVDDYNKWAGDNGFTPFSTST--AITKLSAITGVDVCKLLRTIM- 3050
Query 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWM-----LLTFL 3565
+ + G ILG EDE TP V Q GV Q F V+ W L FL
Sbjct 3051 VKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSF---VRKATSWFWSRCVLACFL 3107
Query 3566 TSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLAT-- 3623
L +V T L F+VY L +MA+ + VKH A++ FLLP+L T
Sbjct 3108 FVLCAIVLFTAVPLKFYVYAAVIL-----LMAVLFIS-FTVKHVMAYMDTFLLPTLITVI 3161
Query 3624 ------------------VAYFNMVYMPASWVMRIMTWLELADTSLSGYR-LKDCVMYAS 3664
V + + Y P + ++ W+ L + ++ ++ C M +
Sbjct 3162 IGVCAEVPFIYNTLISQVVIFLSQWYDPVVF-DTMVPWMFLPLVLYTAFKCVQGCYMNSF 3220
Query 3665 ALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGV 3724
LL+L + ++T N +T + GN W L +
Sbjct 3221 NTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN--------WELFFELVHTTVLA 3265
Query 3725 VTTIMFLARAIVFVCVE----YYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
+ L VF C + Y ++ L +M+ +G+ C CYFGL+ +N+
Sbjct 3266 NVSSNSLIGLFVFKCAKWMLYYCNATYLNNYVLMAVMV--NCIGWLCTCYFGLYWWVNKV 3323
Query 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
F LTLG Y++ VS ++RYM + PPK+ + F NI + GIGG + +ATVQ+K+S
Sbjct 3324 FGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLPIATVQAKLS 3383
Query 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
DVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E + ++ +L L +
Sbjct 3384 DVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGECMDNLLGMLITLFCIDS 3443
Query 3901 AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYE----QAVANGDSEVVLKK 3956
+D++ C+++L LQ++ EFS +PSYA Y A+ YE + G ++ L
Sbjct 3444 TIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAA 3503
Query 3957 LKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRK 4016
+K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K
Sbjct 3504 YRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKK 3563
Query 4017 LDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQ 4076
+D++ LN + + A G VPL +P+ + KL +V+PD T+ +G TY++ +W I
Sbjct 3564 IDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNID 3623
Query 4077 QVVDADSKIVQLSEINMD-----NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQ 4128
V+DAD + + + N+AWPL V R V LQNNEL P ++
Sbjct 3624 TVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNKVDVVLQNNELMPHGVKT 3683
Query 4129 MSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEP 4188
+C AG Q C+ ++ YY N G V A+ S + +LK A F G IY +L+P
Sbjct 3684 KACVAGVDQAHCSVES-KCYYTNISGNSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDP 3741
Query 4189 PCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFC 4247
PC+F +V YLYFIK ++ RGMVLG+++ V LQ+ G+ TE +LS C
Sbjct 3742 PCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLC 3801
Query 4248 AFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYC 4307
+FAVDPA Y Y+A+G QP+ NCVKML H G+G AIT P DQ+S+GGAS CLYC
Sbjct 3802 SFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYC 3861
Query 4308 RCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQL 4363
R HI HP N G C KG +VQIPTT DPVGF LRN VCTVC W GYGC CD L
Sbjct 3862 RAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSL 3920
Query 4364 REPLMQSAD-------ASTFLN 4378
R+P +LN
Sbjct 3921 RQPKSSVQSVAGASDFDKNYLN 3942
Score = 164 bits (415), Expect = 3e-38, Method: Composition-based stats.
Identities = 74/349 (21%), Positives = 131/349 (38%), Gaps = 46/349 (13%)
Query 879 AVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAEC 938
AV Q V D+L + G +D A L ++ + + +
Sbjct 872 AVKPLPQKVVDVLGDWGEAVD----AQEQLCQQEPLQHTFEEPVENSTGSSKTMTEQVVV 927
Query 939 EEEEIDE-------------TCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDT 985
E++E+ E T ++ L F E V +++ + +
Sbjct 928 EDQELPVVEQDQDVVVYTPTDLEVAKETAEEVDEFILIFAVPKEEVVSQKDGAQ-IKQEP 986
Query 986 TEQSEIEPEPE--------PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVN 1037
+ + + E + T E+P +F Y ++ + I K IVN
Sbjct 987 IQVVKPQREKKAKKFKVKPATCEKP--KFLEYKTCVGDLTVV---IAKALDEFKEFCIVN 1041
Query 1038 AANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCL-HVV 1096
AAN H+ HG GVA A+ + +DY+K +GP + +C+ +VV
Sbjct 1042 AANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ---RLVTPSFVKGIQCVNNVV 1098
Query 1097 GPNLNAGEDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIA 1154
GP + L AAY+N ++ + P+LS GIFG ++ + +R +
Sbjct 1099 GPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGVD----FKMSIDAMRE-AFEG 1153
Query 1155 VNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVD 1203
+ L + +++D KQ+ TED + +S+V KP D
Sbjct 1154 CTIRVLLFSLSQEHIDYFDVTC---KQKTIYLTEDG-VKYRSIVLKPGD 1198
Score = 41.2 bits (95), Expect = 0.51, Method: Composition-based stats.
Identities = 41/255 (16%), Positives = 87/255 (34%), Gaps = 28/255 (11%)
Query 635 LSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVT 694
+ V+F W+ + IV V + C + +D ++ + +
Sbjct 512 FTKVVDFCDKHWKGFCVQLKRAKLIVTETFCVLKGVAQHCFQLLLDAIHSLYK------S 565
Query 695 IAGAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSE 754
L ++ + G+++ G E + +++ ++ S D + +
Sbjct 566 FKKCALGRIHGD--LLFWKGGVHKIVQDGDEIWFDAIDSVDVEDLGVVQEKSIDFEVCDD 623
Query 755 EVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFR 814
+ +N ++ D N + KD+ Y L A N V +
Sbjct 624 VTLPENQPGHMVQIEDDGK------------NYMFFRFKKDENIYYTPMSQLGAINVVCK 671
Query 815 LKGGAPIKGVTFGEDTVWEV--QGYKNVRITFELD-ERVDKVLNEKCSV-YTVESGTEVT 870
G K VTFGE TV E+ ++++ E E + + + V++ V
Sbjct 672 AGG----KTVTFGETTVQEIPPPDVVPIKVSIECCGEPWNTIFKKAYKEPIEVDTDLTVE 727
Query 871 EFACVVAEAVVKTLQ 885
+ V+ E + L+
Sbjct 728 QLLSVIYEKMCDDLK 742
>sp|P0C6V3|R1A_IBVB Replicase polyprotein 1a OS=Avian infectious
bronchitis virus (strain Beaudette) OX=11122 GN=1a PE=1 SV=1
Length=3951
Score = 2487 bits (6446), Expect = 0.0, Method: Composition-based stats.
Identities = 852/2962 (29%), Positives = 1326/2962 (45%), Gaps = 317/2962 (11%)
Query 1541 EVKTIKVFTTVDNTNLHTQLVDMSMTYGQQFGPTYLDGADVTKIKPHVNHEGKTFFVLPS 1600
K ++ T D + ++ + G QFG Y V + E K +P+
Sbjct 1174 TCKQKTIYLTEDGVKYRSIVLKPGDSLG-QFGQVYAKNKIVFTA---DDVEDKEILYVPT 1229
Query 1601 DDTLRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNNCYLSSVLLAL 1660
D E Y+ LD Y+ L +KW ++W D NC++SS ++ L
Sbjct 1230 TDKSILE----YYGLDAQKYVIYLQTL--AQKWNVQYRDNFLILEWRDGNCWISSAIVLL 1283
Query 1661 QQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVGELGDVRETMTHLLQHANLES 1720
Q +++F L EA+ + GD +F A A VG+ D + +L +H + +
Sbjct 1284 QAAKIRFKG-FLTEAWAKLLGGDPTDFVAWCYASCTAKVGDFSDANWLLANLAEHFDADY 1342
Query 1721 AKRVLNV-VCKHCGQKTTTLTGVEAVM-YMGTLSYDNLKTGVSIPCVCGRDATQYLVQQE 1778
L V +CG K+ L G+EA + + + + KT S CG + T +++
Sbjct 1343 TNAFLKKRVSCNCGIKSYELRGLEACIQPVRATNLLHFKTQYSNCPTCGANNTDEVIEAS 1402
Query 1779 SSFVMMSAP--PAEYKLQQGTFLCANEYTGNYQCGH-YTHITAKETLYRIDGAHLTKMSE 1835
++++ A PA + + + G+ GH YT D +
Sbjct 1403 LPYLLLFATDGPATVDCDEDA-VGTVVFVGSTNSGHCYTQAAG----QAFDNLAKDRKFG 1457
Query 1836 YKGPVTDVFYKETSYTTTIKPVSYKLDGVTYTEIEPKLDGYYKKDNAYYTEQPIDLVPTQ 1895
K P Y ++ K ++ +
Sbjct 1458 KKSPYITAMYTRFAFKNETSLPVAKQSKGKSKSVKEDVSNL------------------A 1499
Query 1896 PLPNASFDNFKLTCSNTKFADDLNQMTGFTKPASRELSVTFFPDLNGDVVAIDYRHYSAS 1955
ASFDN D Q + L V PD ++ Y +
Sbjct 1500 TSSKASFDNL----------TDFEQW--YDSNIYESLKVQESPD--------NFDKYVSF 1539
Query 1956 FKKGAKLLHKPIVWHINQATTKTTFKPNTWCLRCLWSTKPVDTSNSFEVLAVEDTQGMDN 2015
T + + P T +R + S + + F DT
Sbjct 1540 ------------------TTKEDSKLPLTLKVRGIKSVVDFRSKDGFIYKLTPDTD---- 1577
Query 2016 LACESQQPTSEEVVENPTIQKEVIECDVKTTEVVGNVILKPSDEGVKVTQELGHEDLMAA 2075
S+ P V++ + +K V GN ++ L
Sbjct 1578 --ENSKAPVYYPVLDAIS---------LKAIWVEGNANFVVGHPNY-YSKSLHIPTFWEN 1625
Query 2076 Y---------VENTSITIKKPNELSLALGLKTIATHGIAAINSVPWSKILAYVKPFLGQA 2126
+ ++ + + L+ IA V S + +G+A
Sbjct 1626 AENFVKMGDKIGGVTMGLWRAEHLNKP---NLERIFNIAKKAIVGSSVVTTQCGKLIGKA 1682
Query 2127 AITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKSTNSRIRASLPTTIAKNSVKSVAKL 2186
A ++ R + + + + F + + + K + +
Sbjct 1683 ATFIADKVGGGVVRNITDSIKGLCGITRG--HFERKMSPQF--------LKTLMFFLFYF 1732
Query 2187 CLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVREL 2246
+ + V S K + LL++ S + VL S C ++
Sbjct 1733 LKASVKSVVASYKTVLCKVVLATLLIVWFVYTSNPVMFTGIRVL-DFLFEGSLCGPYKDY 1791
Query 2247 YLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWVL 2306
+S +V + +C F C +CL DSL Y +++ YK + G W
Sbjct 1792 GKDSFDV--LRYCADDFICRVCLHDKDSLHLYKHAYSVE---QVYKDAAS--GFIFNWNW 1844
Query 2307 AYMLFTKFFYLLGLSAIMQVFFGYFASHFISNS--------WLMWFIISIVQMAPVSAMV 2358
Y++F F V Y + + NS +L WF V +
Sbjct 1845 LYLVFLILFVKPVAGF---VIICYCVKYLVLNSTVLQTGVCFLDWF---------VQTVF 1892
Query 2359 RMYIFFASFYYIWKSYV-----HIMDGCTSSTCMMCYKRNRATRVECTTIVNGMKRSFYV 2413
+ F + +Y W Y H + C TC +C + R+ R E + +V G K+ +V
Sbjct 1893 SHFNFMGAGFYFWLFYKIYIQVHHILYCKDVTCEVCKRVARSNRQEVSVVVGGRKQIVHV 1952
Query 2414 YANGGRGFCKTHNWNCLNCDTFCTGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVAV 2473
Y N G FCK HNW C NCD + +TF+S EVA +LS + KR + PT + ++VD +
Sbjct 1953 YTNSGYNFCKRHNWYCRNCDDYGHQNTFMSPEVAGELSEKLKRHVKPTAYAYHVVDEACL 2012
Query 2474 KNGALHLYFD-KAGQKTYERHPLSHFVNLDNL-RANNTKGSLPINVIVFDGKSKCDESA- 2530
+ ++L + K + F D L +A K +L I DG C+ +
Sbjct 2013 VDDFVNLKYKAATPGKDSASSAVKCFSVTDFLKKAVFLKEALKCEQISNDGFIVCNTQSA 2072
Query 2531 -----SKSASVYYSQLMCQPILLLDQALVSDVGDSTEVSVKMFDAYVDTFSATFSVPMEK 2585
+K+A++YY+Q +C+PIL+LDQAL + VS + D S+ SV
Sbjct 2073 HALEEAKNAAIYYAQYLCKPILILDQALYEQL-VVEPVSKSVIDKVCSILSSIISVD--- 2128
Query 2586 LKALVATAHSELAKGVALDGVLSTFVSAARQGVVDTDVDTKDVIECLKLSHHSDLEVTGD 2645
TA G D +LS ++ ++ H+ D++ TGD
Sbjct 2129 ------TAALNYKAGTLRDALLSI-------------TKDEEAVDMAIFCHNHDVDYTGD 2169
Query 2646 SCNNFMLTY-NKVENMTPRDLGACIDCNARHINAQVAKSHNVSLIWNVKDYMSLSEQLRK 2704
N + +Y +TPRD G I+ +A N +V + ++W + + LS+ K
Sbjct 2170 GFTNVIPSYGIDTGKLTPRDRGFLINADASIANLRVKNAP--PVVWKFSELIKLSDSCLK 2227
Query 2705 QIRSAAKKNNIPFRLTCATTRQVVNVITTKISL--KGGKIVS---TCFKLMLKATLLCVL 2759
+ SA K+ + F +T + +QV+ T K+ + K G IVS CFK K L+ +
Sbjct 2228 YLISATVKSGVRFFITKSGAKQVIACHTQKLLVEKKAGGIVSGTFKCFKSYFKWLLIFYI 2287
Query 2760 AALVC---YIVMPVHTLSIHDGY----TNEIIGYKAIQDGVTRDIISTDDCFANKHAGFD 2812
C Y M V +H Y T + G+K I GV R+I+ D CF+NK FD
Sbjct 2288 LFTACCSGYYYMEVSKSFVHPMYDVNSTLHVEGFKVIDKGVLREIVPEDTCFSNKFVNFD 2347
Query 2813 AWFSQRGGSYKNDKSCPVVAAIITREIGFIVPGLPGTVLRAING-DFLH---------FL 2862
A++ G Y N ++CP+V A+I + G + G+PG V ++G F+H ++
Sbjct 2348 AFW---GRPYDNSRNCPIVTAVIDGD-GTVATGVPGFVSWVMDGVMFIHMTQTERKPWYI 2403
Query 2863 PRVFSAVGNICYTPSKLIEYSDFATSACVLAAECTIFKDAMGKPVPYCYD-TNLLEGSIS 2921
P F+ + YT +I F TS + +A C ++ A P YC++ N G++
Sbjct 2404 PTWFNRE-IVGYTQDSIITEGSFYTSIALFSARC-LYLTASNTPQLYCFNGDNDAPGALP 2461
Query 2922 YSELRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDAEYCRHGTCERSEVGICLSTSGRW 2981
+ + P Y +G + P L + VV YCR CE + G C+S + +W
Sbjct 2462 FGSIIPHRVYFQPNGVRLIVPQQILH-TPYVVKFVSDSYCRGSVCEYTRPGYCVSLNPQW 2520
Query 2982 VLNNEHYRALSGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYF 3041
VL N+ Y + GVFCG L+ ++ + V ++ + +I ++V
Sbjct 2521 VLFNDEYTSKPGVFCGSTVRELMFSMVSTFFTGVNP-NIYMQLATMFLILVVVVLIFAMV 2579
Query 3042 MKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLA 3101
+KF+ VF Y V L+++++ ILC+ S L + V Y Y + + + +
Sbjct 2580 IKFQGVFKAYATTVFITMLVWVINAFILCVHSYNSVLAVILLVLYCYASLVTSRNTVIIM 2639
Query 3102 HLQWFAMFSPIVPFWITAIYVFCISLKH---CHWFFNNYLRKRVMFNGVTF-STFEEAAL 3157
H F IVP W+ Y+ I + W + R +++G F ++ AA
Sbjct 2640 HCWLVFTFGLIVPTWLACCYLGFIIYMYTPLFLWCYGTTKNTRKLYDGNEFVGNYDLAAK 2699
Query 3158 CTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALND 3217
TF++ ++KL +E ++ YL+ Y + KY+SG Y +A LA AL+
Sbjct 2700 STFVIRGSEFVKLTNEIG---DKFEAYLSAYARLKYYSGTGSEQDYLQACRAWLAYALDQ 2756
Query 3218 FSNSGADVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDTVY 3277
+ NSG +++Y PP+ SI + LQSGF+K+ PS VE C+V V+ LNGLWL DT+Y
Sbjct 2757 YRNSGVEIVYTPPRYSIGVSRLQSGFKKLVSPSSAVEKCIVSVSYRGNNLNGLWLGDTIY 2816
Query 3278 CPRHVICTAEDMLNPNYEDLLIRKSNHSFLVQAG-NVQLRVIGHSMQNCLLRLKVDTSNP 3336
CPRHV+ + D+L +NH F V V L V+ ++ +L L+ +N
Sbjct 2817 CPRHVL---GKFSGDQWNDVLNLANNHEFEVTTQHGVTLNVVSRRLKGAVLILQTAVANA 2873
Query 3337 KTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDC 3396
+TPKYKF++ G +F++ Y G+ G+Y MR N TI+ SFL G+CGSVGFNI+
Sbjct 2874 ETPKYKFIKANCGDSFTIACAYGGTVVGLYPVTMRSNGTIRASFLAGACGSVGFNIEKGV 2933
Query 3397 VSFCYMHHMELPTGVHAGTDLEGKFYGPFVDRQTAQAAGTDTTITLNVLAWLYAAVINGD 3456
V+F YMHH+ELP +H GTDL G+FYG +VD + AQ D +T N++AWLYAA+I+
Sbjct 2934 VNFFYMHHLELPNALHTGTDLMGEFYGGYVDEEVAQRVPPDNLVTNNIVAWLYAAIISVK 2993
Query 3457 RW------FLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKE 3510
+L T +++D+N A + P + + LSA TG+ V + +
Sbjct 2994 ESSFSLPKWLESTTVSVDDYNKWAGDNGFTPFSTST--AITKLSAITGVDVCKLLRTIM- 3050
Query 3511 LLQNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWM-----LLTFL 3565
+ + G ILG EDE TP V Q GV Q F V+ W L FL
Sbjct 3051 VKNSQWGGDPILGQYNFEDELTPESVFNQIGGVRLQSSF---VRKATSWFWSRCVLACFL 3107
Query 3566 TSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLAT-- 3623
L +V T L F+VY L +MA+ + VKH A++ FLLP+L T
Sbjct 3108 FVLCAIVLFTAVPLKFYVYAAVIL-----LMAVLFIS-FTVKHVMAYMDTFLLPTLITVI 3161
Query 3624 ------------------VAYFNMVYMPASWVMRIMTWLELADTSLSGYR-LKDCVMYAS 3664
V + + Y P + ++ W+ L + ++ ++ C M +
Sbjct 3162 IGVCAEVPFIYNTLISQVVIFLSQWYDPVVF-DTMVPWMFLPLVLYTAFKCVQGCYMNSF 3220
Query 3665 ALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGV 3724
LL+L + ++T N +T + GN W L +
Sbjct 3221 NTSLLMLYQ----FVKLGFVIYTSSNTLTAYTE---GN--------WELFFELVHTTVLA 3265
Query 3725 VTTIMFLARAIVFVCVE----YYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
+ L VF C + Y ++ L +M+ +G+ C CYFGL+ +N+
Sbjct 3266 NVSSNSLIGLFVFKCAKWMLYYCNATYLNNYVLMAVMV--NCIGWLCTCYFGLYWWVNKV 3323
Query 3781 FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCIKVATVQSKMS 3840
F LTLG Y++ VS ++RYM + PPK+ + F NI + GIGG + +ATVQ+K+S
Sbjct 3324 FGLTLGKYNFKVSVDQYRYMCLHKINPPKTVWEVFSTNILIQGIGGDRVLPIATVQAKLS 3383
Query 3841 DVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQG 3900
DVKCT+VVL+ +L +L VE++SK+ V+LHN IL + D E + ++ +L L +
Sbjct 3384 DVKCTTVVLMQLLTKLNVEANSKMHVYLVELHNKILASDDVGECMDNLLGMLITLFCIDS 3443
Query 3901 AVDINRLCEEMLDNRATLQAIASEFSSLPSYAAYATAQEAYE----QAVANGDSEVVLKK 3956
+D++ C+++L LQ++ EFS +PSYA Y A+ YE + G ++ L
Sbjct 3444 TIDLSEYCDDILKRSTVLQSVTQEFSHIPSYAEYERAKNLYEKVLVDSKNGGVTQQELAA 3503
Query 3957 LKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRK 4016
+K+ N+AKS FDRD A+Q+KL+ MA++AMT MYK+AR D+RAK+ S++ +LF+ML+K
Sbjct 3504 YRKAANIAKSVFDRDLAVQKKLDSMAERAMTTMYKEARVTDRRAKLVSSLHALLFSMLKK 3563
Query 4017 LDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVVPDYGTYKNTCDGNTFTYASALWEIQ 4076
+D++ LN + + A G VPL +P+ + KL +V+PD T+ +G TY++ +W I
Sbjct 3564 IDSEKLNVLFDQASSGVVPLATVPIVCSNKLTLVIPDPETWVKCVEGVHVTYSTVVWNID 3623
Query 4077 QVVDADSKIVQLSEINMD-----NSPNLAWPLIVTALRANSA---VKLQNNELSPVALRQ 4128
V+DAD + + + N+AWPL V R V LQNNEL P ++
Sbjct 3624 TVIDADGTELHPTSTGSGLTYCISGANIAWPLKVNLTRNGHNKVDVVLQNNELMPHGVKT 3683
Query 4129 MSCAAGTTQTACTDDNALAYYNNSKGGRFVLALLSDHQDLKWARFPKSDGTGTIYTELEP 4188
+C AG Q C+ ++ YY N G V A+ S + +LK A F G IY +L+P
Sbjct 3684 KACVAGVDQAHCSVES-KCYYTNISGNSVVAAITSSNPNLKVASFLNEAGN-QIYVDLDP 3741
Query 4189 PCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQA-GNATEVPANSTVLSFC 4247
PC+F +V YLYFIK ++ RGMVLG+++ V LQ+ G+ TE +LS C
Sbjct 3742 PCKFGMKVGVKVEVVYLYFIKNTRSIVRGMVLGAISNVVVLQSKGHETEEVDAVGILSLC 3801
Query 4248 AFAVDPAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYC 4307
+FAVDPA Y Y+A+G QP+ NCVKML H G+G AIT P DQ+S+GGAS CLYC
Sbjct 3802 SFAVDPADTYCKYVAAGNQPLGNCVKMLTVHNGSGFAITSKPSPTPDQDSYGGASVCLYC 3861
Query 4308 RCHIDHP----NPKGFCDLKGKYVQIPTTCANDPVGFTLRNTVCTVCGMWKGYGCSCDQL 4363
R HI HP N G C KG +VQIPTT DPVGF LRN VCTVC W GYGC CD L
Sbjct 3862 RAHIAHPGSVGNLDGRCQFKGSFVQIPTT-EKDPVGFCLRNKVCTVCQCWIGYGCQCDSL 3920
Query 4364 REPLMQSAD-------ASTFLN 4378
R+P +LN
Sbjct 3921 RQPKSSVQSVAGASDFDKNYLN 3942
Score = 164 bits (415), Expect = 3e-38, Method: Composition-based stats.
Identities = 74/349 (21%), Positives = 131/349 (38%), Gaps = 46/349 (13%)
Query 879 AVVKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAEC 938
AV Q V D+L + G +D A L ++ + + +
Sbjct 872 AVKPLPQKVVDVLGDWGEAVD----AQEQLCQQEPLQHTFEEPVENSTGSSKTMTEQVVV 927
Query 939 EEEEIDE-------------TCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDT 985
E++E+ E T ++ L F E V +++ + +
Sbjct 928 EDQELPVVEQDQDVVVYTPTDLEVAKETAEEVDEFILIFAVPKEEVVSQKDGAQ-IKQEP 986
Query 986 TEQSEIEPEPE--------PTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVN 1037
+ + + E + T E+P +F Y ++ + I K IVN
Sbjct 987 IQVVKPQREKKAKKFKVKPATCEKP--KFLEYKTCVGDLTVV---IAKALDEFKEFCIVN 1041
Query 1038 AANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCL-HVV 1096
AAN H+ HG GVA A+ + +DY+K +GP + +C+ +VV
Sbjct 1042 AANEHMTHGSGVAKAIADFCGLDFVEYCEDYVKKHGPQQ---RLVTPSFVKGIQCVNNVV 1098
Query 1097 GPNLNAGEDIQLLKAAYENFNSQDIL--LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIA 1154
GP + L AAY+N ++ + P+LS GIFG ++ + +R +
Sbjct 1099 GPRHGDNNLHEKLVAAYKNVLVDGVVNYVVPVLSLGIFGVD----FKMSIDAMRE-AFEG 1153
Query 1155 VNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVD 1203
+ L + +++D KQ+ TED + +S+V KP D
Sbjct 1154 CTIRVLLFSLSQEHIDYFDVTC---KQKTIYLTEDG-VKYRSIVLKPGD 1198
Score = 41.2 bits (95), Expect = 0.51, Method: Composition-based stats.
Identities = 41/255 (16%), Positives = 87/255 (34%), Gaps = 28/255 (11%)
Query 635 LSAGVEFLKDAWEILKFLITGVFDIVKGQIQVASDNIKDCVKCFIDVVNKALEMCIDQVT 694
+ V+F W+ + IV V + C + +D ++ + +
Sbjct 512 FTKVVDFCDKHWKGFCVQLKRAKLIVTETFCVLKGVAQHCFQLLLDAIHSLYK------S 565
Query 695 IAGAKLRSLNLGEVFIAQSKGLYRQCIRGKEQLQLLMPLKAPKEVTFLEGDSHDTVLTSE 754
L ++ + G+++ G E + +++ ++ S D + +
Sbjct 566 FKKCALGRIHGD--LLFWKGGVHKIVQDGDEIWFDAIDSVDVEDLGVVQEKSIDFEVCDD 623
Query 755 EVVLKNGELEALETPVDSFTNGAIVGTPVCVNGLMLLEIKDKEQYCALSPGLLATNNVFR 814
+ +N ++ D N + KD+ Y L A N V +
Sbjct 624 VTLPENQPGHMVQIEDDGK------------NYMFFRFKKDENIYYTPMSQLGAINVVCK 671
Query 815 LKGGAPIKGVTFGEDTVWEV--QGYKNVRITFELD-ERVDKVLNEKCSV-YTVESGTEVT 870
G K VTFGE TV E+ ++++ E E + + + V++ V
Sbjct 672 AGG----KTVTFGETTVQEIPPPDVVPIKVSIECCGEPWNTIFKKAYKEPIEVDTDLTVE 727
Query 871 EFACVVAEAVVKTLQ 885
+ V+ E + L+
Sbjct 728 QLLSVIYEKMCDDLK 742
>sp|P18457|R1AB_CVPFS Replicase polyprotein 1ab (Fragment) OS=Porcine
transmissible gastroenteritis coronavirus (strain FS772/70)
OX=11150 GN=rep PE=3 SV=1
Length=533
Score = 769 bits (1985), Expect = 0.0, Method: Composition-based stats.
Identities = 260/533 (49%), Positives = 361/533 (68%), Gaps = 8/533 (2%)
Query 6546 SSLTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTL--IGESVKT 6603
S + FD + G + F R+ VLI+ +VKGL+ K +N + + +G T
Sbjct 3 SEVVTCFDNSIAGSFERFTTTRDAVLISNNAVKGLSAIK-LQYGLLNDLPVSTVGNKPVT 61
Query 6604 QFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEH 6663
+ Y +K ++Q+ ++Y+TQ R E FKPRS ME DFL + FIQ+Y LE Y FEH
Sbjct 62 WYIYVRKNGEYVEQI-DSYYTQGRTFETFKPRSTMEEDFLSMDTTLFIQKYGLEDYGFEH 120
Query 6664 IVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIP-MDSTVKNYFITDAQTGSSKCVCS 6722
+V+GD S +GG+HL+I + ++ +++F+ DST+K+ IT A SSK VC+
Sbjct 121 VVFGDVSKTTIGGMHLLISQVRLAKMGLFSVQEFMNNSDSTLKSCCITYADDPSSKNVCT 180
Query 6723 VIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQP 6782
+D+LLDDFV IIKS DL+V+SKVV V +D +MLWC++ H++TFYP+LQ+++ W P
Sbjct 181 YMDILLDDFVTIIKSLDLNVVSKVVDVIVDCKAWKWMLWCENSHIKTFYPQLQSAE-WNP 239
Query 6783 GVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRV 6842
G +MP LYK+QRM LE+C+L NYG +P GI NV KYTQLCQYLNT TL VP+ MRV
Sbjct 240 GYSMPTLYKIQRMCLERCNLYNYGAQVKLPDGITTNVVKYTQLCQYLNTTTLCVPHKMRV 299
Query 6843 IHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLI 6902
+H GA GVAPG+ VLR+WLP +LVD+DL D+VSDAD ++ GDC +++ +K+DL+
Sbjct 300 LHLGAAGASGVAPGSTVLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTSLYIEDKFDLL 359
Query 6903 ISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHF 6962
+SD+YD TK + EN SK+GFFTY+ GFIK+KL+LGGS+A+KITE SWN DLY+L+ F
Sbjct 360 VSDLYDGSTKSIDGENTSKDGFFTYINGFIKEKLSLGGSVAIKITEFSWNKDLYELIQRF 419
Query 6963 SWWTAFVTNVNASSSEAFLIGANYLGK--PKEQIDGYTMHANYIFWRNTNPIQLSSYSLF 7020
+WT F T+VN SSSE FLIG NYLG K +DG MHANYIFWRN+ + LS S+
Sbjct 420 EYWTVFCTSVNTSSSEGFLIGINYLGPYCDKAIVDGNIMHANYIFWRNSTIMALSHNSVL 479
Query 7021 DMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVNN 7073
D KF + +++LKE ++N+M+ LL KG+L+IR N +++ + VN
Sbjct 480 DTPKFKCRCNNALIVNLKEKELNEMVIGLLRKGKLLIRNNGKLLNFGNHFVNT 532
>sp|P12723|R1AB_IBVK Replicase polyprotein 1ab (Fragment) OS=Avian
infectious bronchitis virus (strain KB8523) OX=11126 GN=rep
PE=3 SV=1
Length=521
Score = 634 bits (1634), Expect = 0.0, Method: Composition-based stats.
Identities = 244/524 (47%), Positives = 346/524 (66%), Gaps = 17/524 (3%)
Query 6558 GQVDLFRNARNGVLITEGSVKGLTPSKGPAQASV-NGVTLIGESVKTQFNYFKKVDGIIQ 6616
G F A N VL++ K + + P+ V NG++L + +K+V+G
Sbjct 2 GGGQSFLAADNAVLVSTQCYKRHSYVEIPSNLLVQNGMSLKDGA---NLYVYKRVNGAFV 58
Query 6617 QLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGG 6676
LP T TQ R E F+PRS +E DFL+++ ++F+++Y + +HI+YG+ QLGG
Sbjct 59 TLPNTLNTQGRSYETFEPRSDVERDFLDMSEEDFVEKYG-KDLGLQHILYGEVDKPQLGG 117
Query 6677 LHLMIGLAKRSQDSPLKLEDFIPMDST-VKNYFITDAQTGSSKCVCSVIDLLLDDFVEI- 6734
LH +IG+ + + + L + DS ++NYF+ A GS K VC+V+DLLLDDF+E+
Sbjct 118 LHTVIGMYRLLRANKLNAKSVTNSDSDVMQNYFVL-ADNGSYKQVCTVVDLLLDDFLELL 176
Query 6735 --IKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGVAMPNLYKM 6792
I ++ + SKVV V+IDY I+FM W +DG ++T YP+LQ++ W G MP LYK+
Sbjct 177 RNILNEYGTNKSKVVTVSIDYHSINFMTWFEDGSIKTCYPQLQSA--WTCGYNMPELYKV 234
Query 6793 QRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKG 6852
Q ++E C++ NYG +P GIMMNVAKYTQLCQYL+ T+ VP+NMRV+HFGAGSDKG
Sbjct 235 QNCVMEPCNIPNYGVGITLPSGIMMNVAKYTQLCQYLSKTTVCVPHNMRVMHFGAGSDKG 294
Query 6853 VAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMY---DP 6909
VAPG+ VL+QWLP GTLLVD+D+ D+VSDA +++ DC T +K+DL+ISDMY D
Sbjct 295 VAPGSTVLKQWLPEGTLLVDTDIVDYVSDAHVSVLSDCNKYKTEHKFDLVISDMYTDNDS 354
Query 6910 RTKHVTK-ENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAF 6968
+ KH N+ + F YL F++ LALGGS AVK+TE SW+ LY + +WWT F
Sbjct 355 KRKHGGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKLTETSWHESLYDIAQDCAWWTMF 414
Query 6969 VTNVNASSSEAFLIGANYLGKP-KEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFPL 7027
T VNASSSEAFLIG NYLG K ++ G T+HANYIFWRN N +Q S+YS+FD++KF L
Sbjct 415 CTAVNASSSEAFLIGVNYLGASVKVKVSGKTLHANYIFWRNCNYLQTSAYSIFDVAKFDL 474
Query 7028 KLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILV 7071
+L+ T V++LK Q D++++L++ G+L++R+ +SD V
Sbjct 475 RLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDSFV 518
>sp|P0C6V7|R1AB_BEV Replicase polyprotein 1ab OS=Berne virus OX=11156
GN=rep PE=1 SV=1
Length=6857
Score = 620 bits (1598), Expect = 1e-175, Method: Composition-based stats.
Identities = 139/598 (23%), Positives = 257/598 (43%), Gaps = 51/598 (9%)
Query 4787 DFYDFAVSKGFFKEGSSV--ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEV 4844
FYD + + G K+F++ + A++D YY Y + L V +
Sbjct 4908 PFYDVGLCQELTDAGVDCGEAFKYFYYLSNPAGALADVCYYDYQGTGFYSPKLLAGVYDF 4967
Query 4845 VDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWG-KARLYYDSMSYEDQDALFAYTKRN 4903
+ + +CY IN + + N G + Y ++ E+ LF Y ++
Sbjct 4968 MKRVTECYR---INERFTYEQAKPRKSSMGINITGYQQDAVYRALGPENIARLFEYAQKA 5024
Query 4904 VIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKL---LKSIAATRGATVVIGT 4960
+P T++ K+A+SAK RARTV+ S ++ R H+ + + +A G +IG
Sbjct 5025 PLPFCTKIITKFALSAKARARTVSSCSFIASTIFRFAHKPVTSKMVEVAQNSGGFCLIGV 5084
Query 4961 SKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHR 5020
SK+ + LK Y +E + G DY KCDR P R + + +L +
Sbjct 5085 SKYGLKFSKFLKDKYGAIEGFDVFGSDYTKCDRTFPLSFRALTAALLYE----LGEWDEK 5140
Query 5021 FYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLS-- 5078
+ NE + + ++C G L KPGGTSSGDATTA++N+ +N +LS
Sbjct 5141 SWLYLNEVNSYMLDTMLCDGMLLNKPGGTSSGDATTAHSNTFYNYMVHYVVAFKTILSDL 5200
Query 5079 TDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSN 5138
++GNK+ +R H Y + V + +++ + + ++ + LSDD+ + ++
Sbjct 5201 SEGNKV----MRIAAHNAYTT--GDYQVFNTLLEDQF---QTNYFLNFLSDDSFI-FSKP 5250
Query 5139 YAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYL 5198
A + + + +NF L + + + K W+ + EFCS H ++K +Y +L
Sbjct 5251 EALK--IFTCENFSNKLQTILHTKVDQTKSWSTKGHIE---EFCSAH--IIKTDGEYHFL 5303
Query 5199 PYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIR 5258
P R+L + +D + D M RFV++ ++ +++ + + +F ++L ++
Sbjct 5304 --PSRGRLLASLLILDKLSDVDIYYM--RFVAILCESAVYSRYQPEFFNGLFQVFLDKVQ 5359
Query 5259 KLH-----DELTGHML--DMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVG---ACVL 5308
+ D +L + Y ++ N+ + E Q C
Sbjct 5360 QFRKDYCCDPCPPQLLEREFYENLVFTSNSEVGIVDCYLENFKLQCEFKQQANFDKVCFC 5419
Query 5309 CNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYL 5366
C + C C LC C Y HV+ ++H V + + C C ++ +LY+
Sbjct 5420 CPNPAVSVCEECYVPLPLCAYCYYVHVVISNHSKVE--DKFKCF---CGQDNIRELYI 5472
Score = 325 bits (834), Expect = 7e-87, Method: Composition-based stats.
Identities = 96/388 (25%), Positives = 170/388 (44%), Gaps = 60/388 (15%)
Query 6605 FNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHI 6664
+ + + +LP+T F+ R L + + + +LA++ + H+
Sbjct 6438 YYLQQGKGESLFELPDTLFSTGR-LYNLDHDAAQNFNVKQLAIETMPNNH--------HV 6488
Query 6665 VYGDFSH--GQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDA----QTGSSK 6718
GDF+ +GG+H ++ L S + NY A G +
Sbjct 6489 FSGDFTEVGTDIGGVHHVVALNGYK-------------GSIIPNYVKPIATGLINVGRAV 6535
Query 6719 CVCSVIDLLLDDFVEIIKSQDLSV-ISKVVKVTIDYAEISFMLWCK-DGHVETFYPKLQA 6776
+++D+ + E +K Q V +SKV+ V ID+ ++ FM++ + ++TFYP+
Sbjct 6536 KRTTLVDVCANQLYEKVKQQLEGVKVSKVIFVNIDFQDVQFMVFANGEDDIQTFYPQKDF 6595
Query 6777 SQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENA-VIPKGIMMNVAKYTQLCQYLNTLTLA 6835
+++ PN+ + DL+NYG+N +P+ + N AKYTQ+C ++ +
Sbjct 6596 VRSY---YEWPNILP---QIESHYDLKNYGQNPTFMPQPV--NFAKYTQICTFIQD-HVK 6646
Query 6836 VPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHT 6895
V N V H GA G +PG VL + L+ D+ D+ + + D +
Sbjct 6647 VARNALVWHLGAAGVDGCSPGDIVLSSFFKE-CLVYSWDIKDY------STLLDKHSYDC 6699
Query 6896 ANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSW-NAD 6954
+ +LI+SD+Y+ + +D +LALGG+I K TE S +
Sbjct 6700 NFRPNLIVSDIYNVSSNVSEVLDDC------------VHRLALGGTIVFKTTESSRPDIQ 6747
Query 6955 LYKLMGHFSWWTAFVTNVNASSSEAFLI 6982
L + +FS F VN SSSE F++
Sbjct 6748 LSQFTKYFSAVQFFTAGVNTSSSEVFVV 6775
Score = 185 bits (470), Expect = 1e-44, Method: Composition-based stats.
Identities = 68/306 (22%), Positives = 117/306 (38%), Gaps = 24/306 (8%)
Query 5575 MQKYSTLQGPPGTGKSHFAIG--LALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS 5632
+ + + GPPGTGK+ F L+ S R VY A +H V + EK +D
Sbjct 5659 YENVTFVMGPPGTGKTTFVYDTYLSKASSSNRFVYCAPTHRLVGDMDEK------VDGAV 5712
Query 5633 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5692
+ R + + + + CT N LP + +++ DE+S+ + + + +
Sbjct 5713 VVSAYNDRTYRNPVWNKDDSYG-VLLCTHNTLPFIKSAVLIADEVSLIPPHVMIKI-LSM 5770
Query 5693 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5752
K V +GDP QL +P K + + F L++ +L C RCP +I+
Sbjct 5771 GFKKVVLLGDPFQL-SPVYKNHKVHFKYDTF----YLLQLATQKRYLTACYRCPPQILSA 5825
Query 5753 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVF 5812
S D + + G VS + Q V L++ V
Sbjct 5826 FSKPYCDVGVDLVSFNNKP-------GKFDIIVSKQLANIQDFSVLSVLSKEYPG--YVI 5876
Query 5813 ISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIG 5872
+ Y + A + T+DSSQG+ + + S VNR V +R+
Sbjct 5877 LVNYRAAVDYAMQNGLGDVTTIDSSQGTTAANHLLVLFGASNFSKTVNRVIVGCSRSTTH 5936
Query 5873 ILCIMS 5878
++ +
Sbjct 5937 LVVVCC 5942
Score = 152 bits (384), Expect = 1e-34, Method: Composition-based stats.
Identities = 69/303 (23%), Positives = 113/303 (37%), Gaps = 24/303 (8%)
Query 881 VKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFSSR--MYCSFYPPDEEEEDDAEC 938
K+ + M ++ + FD+A S + S PD A
Sbjct 1564 EKSKDDIFKAFNTMSLEQKKVLSHFCGEFDEAYTLQTMSDEISFESSAYPDVVACSLAYI 1623
Query 939 EEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPT 998
E+ T + E L+ G+ E V V+ + +++ + E+ E +
Sbjct 1624 LGYEMCLTVKVNAKNEK------LDIGSQCERVFVDYDVKKNEWTLSPEEGEDSDDNLDL 1677
Query 999 PEEPVNQF---TGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNK 1055
P E +F + L + + +K Q +VN AN LKHGGG+A ++
Sbjct 1678 PFEQYYEFKIGQTNVVLVQDDFKSVFEFLKSEQGV--DYVVNPANSQLKHGGGIAKVISC 1735
Query 1056 ATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKC--LHVVGPNLNAGEDIQLLKAAY 1113
+Q S++YI N + V + G L KK +H VGP ++ G+ Q L A+
Sbjct 1736 MCGPKLQAWSNNYITKNKTVPVTKAIKSPGFQLGKKVNIIHAVGPRVSDGDVFQKLDQAW 1795
Query 1114 ENF----NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT-----QVYIAVNDKALYEQV 1164
+ Q +L +LS GIFG S + V V++ N Y Q
Sbjct 1796 RSVFDLCEDQHTILTSMLSTGIFGCTVNDSFNTFLSNVARLDKSLVVFVVTNMVEQYNQA 1855
Query 1165 VMD 1167
Sbjct 1856 FAV 1858
Score = 113 bits (283), Expect = 8e-23, Method: Composition-based stats.
Identities = 35/101 (35%), Positives = 51/101 (50%), Gaps = 7/101 (7%)
Query 6085 FVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHSVGF--DYVYNPF 6142
F+L++ +L S+K++V+ C C + A C Y C N G + N
Sbjct 6077 FILYSCSNDLKSLKFYVEFDTCYFCS-CGEMAICL-MRDGNYKCRNCYGGMLISKLVNCK 6134
Query 6143 MIDVQQWGFTGNLQSNHDQHCQ-VHGNAHVASCDAIMTRCL 6182
+DVQ+ LQ HD CQ HG++H A CDA+MT+CL
Sbjct 6135 YLDVQKERV--KLQDAHDAICQQFHGDSHEALCDAVMTKCL 6173
Score = 54.7 bits (130), Expect = 5e-05, Method: Composition-based stats.
Identities = 47/211 (22%), Positives = 83/211 (39%), Gaps = 35/211 (17%)
Query 4384 SAARLTPCGTGT-STDVVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVK 4442
SA R G + D+ E AG K K+N + + + F++K
Sbjct 4575 SACRHLCFQNGAYQSSRSKHYIDLATEYNAGIVKVNKSNTHSVEYQSKR-------FMIK 4627
Query 4443 RHTMSNYQHEETIYNLVK--DCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYAL 4500
R +++ + L K P++ H + + R +++++ DLVYA+
Sbjct 4628 RV------KDQSEFALAKTAFLPSIIPHHM----EKQNGEWFLIRGPTSQWSLGDLVYAI 4677
Query 4501 RHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQ 4560
D+ D L E +N D++ + + F+ N + ++L
Sbjct 4678 WLGDQ---DYLSECGFVFNPSRDEFLDDANQRSFLAN------------LLEPAILNFSH 4722
Query 4561 FCDAMRDAGIVGVLTLDNQDLNGNWYDFGDF 4591
++ + LTLDN DLNG YDFGD+
Sbjct 4723 IYWQVKMCKVPYKLTLDNVDLNGQLYDFGDY 4753
Score = 51.6 bits (122), Expect = 4e-04, Method: Composition-based stats.
Identities = 56/246 (23%), Positives = 94/246 (38%), Gaps = 41/246 (17%)
Query 3005 ANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLM 3064
I +P V + V +V+ +I + + +Y F + +VV LLF+
Sbjct 3055 FEIISPYV--FVFIVVIFTVIFLILIRLYIVMYSY--------FKVFTYVVFK--LLFVN 3102
Query 3065 SFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFC 3124
+L +V +PGV L + + V FL +L + ++F I+P++ ++F
Sbjct 3103 IIMVLFVVCLPPLVPGVV----FVLALWLCDSVMFLLYLAFLSLF--ILPWFYVLFFLFM 3156
Query 3125 ISLKHCHWFFNNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNR 3183
+ W + + +G+TF TFE+ + C F LN + + LL +
Sbjct 3157 VGGFVFWWMMRSADVVHLTTDGLTFNGTFEQISKCVFPLNP----LIVNRMLLDCQMSHS 3212
Query 3184 YLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGF 3243
L +K K G LA + +G YQP S QS F
Sbjct 3213 DLVEKSKLKTTEGK-------------LANEMMKVFMTGETSYYQPSNFSF-----QSVF 3254
Query 3244 RKMAFP 3249
K P
Sbjct 3255 SKATSP 3260
>sp|P0C6V8|R1AB_BRV1 Replicase polyprotein 1ab OS=Breda virus
1 OX=360393 GN=rep PE=2 SV=1
Length=6733
Score = 612 bits (1578), Expect = 2e-173, Method: Composition-based stats.
Identities = 139/598 (23%), Positives = 251/598 (42%), Gaps = 51/598 (9%)
Query 4787 DFYDFAVSKGFFKEGSSV--ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEV 4844
YD + + G K+F++ + A++D +Y Y + L V +
Sbjct 4784 PLYDVGLCQELTDAGVDCGEAFKYFYYLSNPAGALADVCFYDYQGTGFYSPKLLAGVYDF 4843
Query 4845 VDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWG-KARLYYDSMSYEDQDALFAYTKRN 4903
+ + CY + + + N G + Y ++ E+ LF Y ++
Sbjct 4844 MKRVTTCYK---TDERFTYEQAKPRKSSMGINITGYQQDAVYRALGPENITKLFEYAQKA 4900
Query 4904 VIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKL---LKSIAATRGATVVIGT 4960
+P T++ K+A+SAK RARTV+ S ++ R H+ + + +A +IG
Sbjct 4901 PLPFCTKIITKFALSAKARARTVSSCSFIASTIFRFAHKPVTSKMVEVAQNSQGFCLIGV 4960
Query 4961 SKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHR 5020
SK+ + LK Y +E + G DY KCDR P R + + +L
Sbjct 4961 SKYGLKFSKFLKDKYGAIEQFDVFGSDYTKCDRTFPLSFRALTAALLYE----LGGWEED 5016
Query 5021 FYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLS-- 5078
+ NE + + ++C G L KPGGTSSGDATTA++N+ +N +LS
Sbjct 5017 SWLYLNEVNSYMLDTMLCDGMLLNKPGGTSSGDATTAHSNTFYNYMVHYVVAFKTILSDL 5076
Query 5079 TDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSN 5138
+D NK+ +R H Y + V + ++E + + ++ + LSDD+ + ++
Sbjct 5077 SDCNKV----MRIAAHNAYTT--GDYGVFNTLLEEQF---QTNYFLNFLSDDSFI-FSKP 5126
Query 5139 YAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYL 5198
A + + + +NF L + + K W T + EFCS H ++K +Y +L
Sbjct 5127 GALK--IFTCENFSNKLQTILHTKVDLTKSWATTGHIE---EFCSAH--IIKTDGEYHFL 5179
Query 5199 PYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIR 5258
P R+L + +D + D M RFV++ ++ +++ + + +F ++L ++
Sbjct 5180 --PSRGRLLASLLILDKLSDVDIYYM--RFVAILCESAVYSRYQPEFFNGLFQVFLDKVQ 5235
Query 5259 KLH-----DELTGHMLD--MYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVG---ACVL 5308
+ D +LD Y ++ NT + E Q G C
Sbjct 5236 QFRKDYCCDPCPTQLLDRQFYENLVFTSNTEVGLVDCYLENFKLQCEFKQQAGFDRVCFC 5295
Query 5309 CNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYL 5366
C + C C LC C Y HV+ +SH + + + C C D+ +L++
Sbjct 5296 CPNPAVSVCEECYVPLPLCAYCYYVHVVISSHCKIE--DKFKCP---CGQDDIRELFI 5348
Score = 320 bits (820), Expect = 3e-85, Method: Composition-based stats.
Identities = 99/388 (26%), Positives = 172/388 (44%), Gaps = 60/388 (15%)
Query 6605 FNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHI 6664
+ +++LPET F+ R L + + + +LA++ + + H+
Sbjct 6314 YYLQLGNGESLRELPETLFSTGR-LYNLEHDPSKNFNVQQLAIETIPKNH--------HV 6364
Query 6665 VYGDFSH--GQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDA----QTGSSK 6718
GDF+ +GG+H ++ L S + NY A G S
Sbjct 6365 FAGDFTDVGTDIGGVHHVVALNGYK-------------GSIIPNYVKPIATGLINVGRSV 6411
Query 6719 CVCSVIDLLLDDFVEIIKSQDLSV-ISKVVKVTIDYAEISFMLWCK-DGHVETFYPKLQA 6776
+++D+ + E +K Q V +SKV+ V ID+ E+ FM++ K + ++TFYP+ +
Sbjct 6412 KRTTLVDVCANQLYEKVKQQIAGVKVSKVIFVNIDFQEVQFMVFAKGEDDIQTFYPQKEF 6471
Query 6777 SQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENA-VIPKGIMMNVAKYTQLCQYLNTLTLA 6835
+++ P + L DL+NYG++ +P+ + N AKYTQ+C ++ +
Sbjct 6472 IRSY---YEWPTILP---ELESHYDLKNYGQDPQFMPQPV--NFAKYTQICTFIQE-HVK 6522
Query 6836 VPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHT 6895
V N + H GA G +PG VL + L+ D+ D+ TL+ +
Sbjct 6523 VARNSLIWHVGAAGIDGCSPGDIVLSSFFKE-CLVYSWDVKDY-----DTLL-EKHNYDC 6575
Query 6896 ANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSW-NAD 6954
+ +LI+SD+Y+ + D +LALGG+I K TE S +
Sbjct 6576 NFRPNLIVSDVYNVSSNVSEVLEDC------------VHRLALGGTIIFKTTESSRPDIQ 6623
Query 6955 LYKLMGHFSWWTAFVTNVNASSSEAFLI 6982
L K+ +F+ F VN SSSE F++
Sbjct 6624 LSKVTKYFAAVHFFTAGVNTSSSEVFVV 6651
Score = 193 bits (491), Expect = 5e-47, Method: Composition-based stats.
Identities = 69/306 (23%), Positives = 120/306 (39%), Gaps = 24/306 (8%)
Query 5575 MQKYSTLQGPPGTGKSHFAIG--LALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS 5632
+ + + GPPGTGK+ F L+ PS R VY A +H V + EK +D
Sbjct 5535 YENVTFVMGPPGTGKTTFVYNTYLSKASPSNRFVYCAPTHRLVGDMDEK------VDGAV 5588
Query 5633 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5692
+ R +K + + + + CT N LP + +++ DE+S+ + + + +
Sbjct 5589 VVSAYNDRTYRNPVWKKDDSYD-VLLCTHNTLPFIKSAVLIVDEVSLIPPHVMIKI-LSM 5646
Query 5693 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5752
K V +GDP QL +P K + + F L++ +L C RCP +I+
Sbjct 5647 GFKKVVLLGDPFQL-SPVYKNHKVHFKYDTF----YLLQLATQKRYLTACYRCPPQILSA 5701
Query 5753 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVF 5812
S D + + G VS + Q V L++ V
Sbjct 5702 FSKPYCDVGVDLVSFNNKP-------GKFDIIVSKQLANMQDFSVLSVLSKEYPG--YVI 5752
Query 5813 ISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIG 5872
+ Y + A + T+DSSQG+ + + S +NR V +R+
Sbjct 5753 LVNYRAAVDYAMQNGLGDVTTIDSSQGTTAANHLLVLFGASNFSKTINRVIVGCSRSTTH 5812
Query 5873 ILCIMS 5878
++ +
Sbjct 5813 LVVVCC 5818
Score = 144 bits (362), Expect = 5e-32, Method: Composition-based stats.
Identities = 53/203 (26%), Positives = 87/203 (43%), Gaps = 17/203 (8%)
Query 956 DYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGY------ 1009
D + L+ G+S E V V+ + ++ D +T ++ + E P NQ+ +
Sbjct 1589 DGECESLDVGSSLEQVYVDYDVSKNVWDLSTH---LQDDSSDDLELPFNQYYEFKVGRAS 1645
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
+ L + D +K Q +VN AN LKHGGG+A ++ + S++YI
Sbjct 1646 VVLVQDDFKSVYDFLKSEQGV--DYVVNPANNQLKHGGGIAKVISCMCGPKLTSWSNNYI 1703
Query 1070 KLNGPLTVGGSCLLSGHNLAK--KCLHVVGPNLNAGEDIQLLKA----AYENFNSQDILL 1123
K L V + G L K + +HVVGP + + L+A ++N +L
Sbjct 1704 KQYKKLGVTCAIRSPGFQLGKGVQIIHVVGPKSADSDVVNKLEASWRSVFQNVKPDTTVL 1763
Query 1124 APLLSAGIFGAKPLQSLQVCVQT 1146
+LS GIFG S +
Sbjct 1764 TSMLSTGIFGCSVTDSATTLLSN 1786
Score = 116 bits (290), Expect = 1e-23, Method: Composition-based stats.
Identities = 37/134 (28%), Positives = 60/134 (45%), Gaps = 21/134 (16%)
Query 6085 FVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACWNHS--VGFDYVYNPF 6142
F+L++ +L S+K++V+ G C C + A C Y C N + + N
Sbjct 5953 FILYSCSNDLKSLKFYVEFGTNYFCS-CGELAICL-MRDGLYKCRNCYGNMSISKLVNCK 6010
Query 6143 MIDVQQWGFTGNLQSNHDQHCQ-VHGNAHVASCDAIMTRC--LAVHEC------------ 6187
+DVQ+ LQ HD CQ HG++H A CDA+MT+C LA ++
Sbjct 6011 YLDVQKERI--KLQDAHDAICQQFHGDSHEALCDAVMTKCLYLASYDAAFKDTIHVKYKD 6068
Query 6188 FVKRVDWSVEYPII 6201
+ + + P +
Sbjct 6069 LCLEIQYKITSPYV 6082
Score = 53.9 bits (128), Expect = 8e-05, Method: Composition-based stats.
Identities = 54/227 (24%), Positives = 90/227 (40%), Gaps = 31/227 (14%)
Query 3024 VVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYS 3083
VV I I+ ++ F + +VV LLF+ + +L +V +PGV
Sbjct 2944 VVLVAIFTIVFLFLLRMYIVMYSYFKVFTYVVFK--LLFVNTVMVLFVVCLPPLVPGVVF 3001
Query 3084 VFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVM 3143
V L+L + V FL +L ++F I+P++ ++V + W + +
Sbjct 3002 VLALWLC----DSVVFLLYLAVLSLF--ILPWFYVMLFVLIVGGFVFWWMMKSSDVVHLT 3055
Query 3144 FNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTS 3202
+G+TF TFE+ + C F LN + +L + + + L +K K G
Sbjct 3056 PDGLTFNGTFEQVSKCVFPLNPLIVNRLLLDCRMSHSD----LVEKSKLKTTEGK----- 3106
Query 3203 YREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFP 3249
LA + +G YQP S QS F K+ P
Sbjct 3107 --------LATEMMKVFMTGETAYYQPSNFSF-----QSVFSKVVSP 3140
Score = 52.0 bits (123), Expect = 3e-04, Method: Composition-based stats.
Identities = 43/188 (23%), Positives = 73/188 (39%), Gaps = 30/188 (16%)
Query 4404 FDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNLVKDCP 4463
D+ E AG K K+N + F++KR QHE + P
Sbjct 4472 IDLATEYNAGIVKVNKSNTHSVE-------YKGQRFMIKRVKD---QHEFAL-ARTAFLP 4520
Query 4464 AVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDD 4523
++ H + + R T++++ DLVYA+ D+ L E +N D
Sbjct 4521 SIIPHHMVH----QNGEWFLVRGPTTQWSLGDLVYAIWLGDQ---AYLDECGFVFNPSRD 4573
Query 4524 DYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDNQDLNG 4583
++ + + R Y L + ++L + ++ + +TLDN DL G
Sbjct 4574 EFLDDAN----------QRSY--LANLLEPAILSFCEIFHCVKGCQVPYKITLDNLDLKG 4621
Query 4584 NWYDFGDF 4591
YDFGD+
Sbjct 4622 QLYDFGDY 4629
>sp|Q008X6|R1AB_WBV24 Replicase polyprotein 1ab OS=White bream
virus (isolate Blicca bjoerkna L./Germany/DF24/00) OX=766180
GN=rep PE=1 SV=1
Length=6872
Score = 608 bits (1568), Expect = 3e-172, Method: Composition-based stats.
Identities = 142/646 (22%), Positives = 263/646 (41%), Gaps = 90/646 (14%)
Query 4784 FNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNA--AISDYDYYRYNLPTMCDIRQLLFV 4841
+ + FYD + + G ++ + Q G A+ D+ YY YN P D L V
Sbjct 4888 YKRPFYDLDLIQRMNSAGLNLSETTGYHYQCGTTTEAVEDFMYYNYNSPKSFDPSYLKSV 4947
Query 4842 VEVV-DKYFDCYDGGCINANQVIVNNLDKSAGFP-FNKWGK------ARLYYDSMSYEDQ 4893
+ DK+ I+ ++ L+ +G P + G + ++++ +
Sbjct 4948 YTYMRDKFMKI-----ISTDE----KLNHQSGAPRMSSMGVGVSGFFQKTVWNALPEDFS 4998
Query 4894 DALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRG 4953
L + V+P T + K+ K R RT+ G S ++ R H+ + + T
Sbjct 4999 PRLLDTASKTVMPFSTNIVKKFQRQKKTRVRTLGGSSFITSSIFRMLHKPVTNKMVQTAQ 5058
Query 4954 ATV---VIGTSKFYGGWHNMLKTVYSD-VETPHLMGWDYPKCDRAMPNMLRIMASLVLAR 5009
A + +IG SKF G+H L + + +E +MG DY KCDR+ P + R +++ +
Sbjct 5059 ANIGPFLIGISKFNLGFHKYLSAHHPNGIEDCQVMGADYTKCDRSFPVVCRALSAALFYE 5118
Query 5010 KHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAV 5069
+L + NE L + G ++ KPGGT+SGD+TTA++NS +N +
Sbjct 5119 ----LGHLEPNNHWFLNEMFAFLLDPSFISGHIFNKPGGTTSGDSTTAFSNSFYNYFVHL 5174
Query 5070 TANVNALLSTDGNKIADKYVRNLQHRLYEC-LYRNRDVDHEFVDEFYAYLRKHFSMMILS 5128
L+T+ + + + NL H+ + D+ D+ + + + LS
Sbjct 5175 YIQYLTFLTTEMPP-SYQPLCNLAHQAFSTGNTETYDLYFSMADDLNS---TEYFLHFLS 5230
Query 5129 DDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTML 5188
DD+ + + + + NF L ++ AK W+ HEFCS H
Sbjct 5231 DDSFII---SKPTAFPIFTPANFSMKLQNVLGCYVDPAKSWSADGEI---HEFCSSHICK 5284
Query 5189 VKQGDDYVYLPYPDPSRILGAGC----------FVDDIVKTDGTLMIERFVSLAIDAYPL 5238
+ + YV PDP+ +L + +V T L + FV+ +
Sbjct 5285 INEKYQYV----PDPNNMLAGLICAPEPTPQDKLIWKLVATCAELAVFHFVNPTL----- 5335
Query 5239 TKHPNQEYADVFHLYLQYIRKLHDELTGHM-----------LDMYSVMLTNDNTSRYWEP 5287
+ ++FHL ++ LH E +D Y+ ++ +++ +Y
Sbjct 5336 -------FNNIFHL----LQSLHAEFVSEHSVNLLPPKLLEIDFYTDLIDSEDVEQY--S 5382
Query 5288 EFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVN 5347
+ + + ++Q+ C C++ T C C + +C C Y+H++ T H +
Sbjct 5383 FLADTLTEKNIIMQSASQCYFCDNATVSTCSDCTVQYPMCAHCAYEHLMLTDHTPTQVLP 5442
Query 5348 PYVCNAPGCDVTDVTQL----YLGGMSYYCKSHKPPISFPLCANGQ 5389
+V CD TD L +G + C +H ++ PL + +
Sbjct 5443 CHV-----CDQTDPRHLNHTFVMGTVKVACDNHVEGMALPLVDHAR 5483
Score = 290 bits (741), Expect = 5e-76, Method: Composition-based stats.
Identities = 133/636 (21%), Positives = 221/636 (35%), Gaps = 118/636 (19%)
Query 6368 VPLKSATCITRCNLGGAVCRHHANEYRQYLDAYNMMISAGFSLWIYKQFDTYNLWNTFTR 6427
+P +C+ + G C AN + Y + G +L Y T
Sbjct 6268 IPAGYPSCV---KIKGKGCTFCANTIAVITELYEDLAKLGLTLSRPIIQQAYTQVET-QI 6323
Query 6428 LQSLENVAYNVVNKGHFDGHAGEAPVSIINNAVYTKVDGIDVEIFENKTTLPVNVAFELW 6487
LQ++ NV+YN GE + + ++ V ++ I +
Sbjct 6324 LQNITNVSYN---------QFGEMLIQLKDDTVIPFINDFQTSIHN-------------Y 6361
Query 6488 AKRNIKPVPEIKILNNLGVDIAANTVIWDYKREAPAHVSTIGVCTMTDIAKKPTESACSS 6547
+ R+ +P+P I NLG+ + V T I +
Sbjct 6362 SLRSNQPLPNPAIFKNLGIKATLGF--------STPWVPVTTTTTEPHIMSTKILKDNND 6413
Query 6548 LTVLFDGRVEGQVDLFRNARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNY 6607
L +++ F + G I P + +
Sbjct 6414 YYHLSPVQLKASPHAFSSITAGYYIYTT-----PMINIPNET-------------PAYYL 6455
Query 6608 FKKVDGIIQQLPETYFTQSR-DLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVY 6666
V G L Y + +R + F DE+ + H+
Sbjct 6456 THFVHGQSTPLDLGYTSTNRLTTKQFIYTPN---------EDEYKSKLG------HHVSV 6500
Query 6667 GDFSHG--QLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVI 6724
GD S+ +GG+H++ + + P + ++ I A +K + +
Sbjct 6501 GDTSNVSWTIGGMHVLTAFQNITNYQLVSG----PANPIMR---INVALERGNKVETTAL 6553
Query 6725 DLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCK-DGHVETFYPKLQAS------ 6777
D L D+ +I + ++V SK T+D + M + DG ++T YP QA
Sbjct 6554 DTTLQDYYKIATTNKVTV-SKTTFFTLDGGQYRMMNFANPDGTIQTSYPVAQAQSQLITN 6612
Query 6778 -QAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIM--MNVAKYTQLCQYLNTLTL 6834
+ + + P + E D PK +N+ KY Q+C L + L
Sbjct 6613 YRIYPSYITWPTFFTN-----EATDCWAIPNYNAPPKNQTCNINIQKYDQMCD-LFAIDL 6666
Query 6835 AVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVH 6894
+P + H G +K +PG VLRQ+ L DL + VSD +H
Sbjct 6667 KIPVKGHIHHLGNAGNK-YSPGDVVLRQYFDQAHL-TSYDLREVVSD--------IPVLH 6716
Query 6895 TANKWD--LIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWN 6952
++W I+SD+Y P T F + +++ L LGGSI K+TE S
Sbjct 6717 PNDEWKAHFILSDVYAPDT-----------DFTSLALEYMQNHLRLGGSIMWKMTETSI- 6764
Query 6953 ADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLG 6988
+ +++ +F W A VN SSSE FL A Y G
Sbjct 6765 LQVNEIVKYFGSWKAVTFAVNYSSSETFLFCAGYTG 6800
Score = 283 bits (725), Expect = 3e-74, Method: Composition-based stats.
Identities = 76/313 (24%), Positives = 118/313 (38%), Gaps = 44/313 (14%)
Query 4283 QAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL 4342
AI+ P + ++ G S C C DH C G +VQIP ++ F L
Sbjct 4467 IAISQVPVQTIGYLTYAGISVCRQCATKQDHT-----CQYAGYFVQIPREHVSN--IFNL 4519
Query 4343 RNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRVCGVSA-ARLTPCGTG---TSTD 4398
+T C K +C L++ + + G++ P TG S+
Sbjct 4520 TDT--PPCLHNKFTCTTCQPLQQQSKTQQPPLNLVGQCLGLTLDTAFCPFQTGEYKPSSR 4577
Query 4399 VVYRAFDIYNEKVAGFAKFLKTNCCRFQEKDEEGNLLDSYFVVKRHTMSNYQHEETIYNL 4458
Y +I N VA K K N ++ L D+ HE IY +
Sbjct 4578 EFY--INILNNNVASLRKVFKKNTASIPSENGTIMLKDT----------GTAHE--IY-V 4622
Query 4459 VKDCPAVAVHDFFKFRVDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTY 4518
K A + R + D ++ R T Y++ DLVYA D K +L+
Sbjct 4623 AKQLLAKGLPVLQHARFNHDGTDYLIRYYTTPYSLGDLVYAYMVGD------FKHMLLAL 4676
Query 4519 NCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQSLLKTVQFCDAMRDAGIVGVLTLDN 4578
+ D+ + ++ Y N E++R L + + + A + +TLDN
Sbjct 4677 DITDETCLDPGNY----------SSYYNFKEQLRNKLASVIPNVNKILAAELPLAITLDN 4726
Query 4579 QDLNGNWYDFGDF 4591
DLNG YDFGD+
Sbjct 4727 IDLNGFLYDFGDY 4739
Score = 269 bits (688), Expect = 7e-70, Method: Composition-based stats.
Identities = 69/330 (21%), Positives = 137/330 (42%), Gaps = 29/330 (9%)
Query 5547 YVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIG--LALYYPSAR 5604
Y + + + T++ + ++ N ++K + + GPPGTGK+ + + + P+ +
Sbjct 5617 YRKYSKIRRTIHKPRLANRHILN----TLKKATFIIGPPGTGKTTYVMKNFIDTASPANK 5672
Query 5605 IVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNAL 5664
+ Y A +H V ++ + ++ + ++ + +NS + + T A+
Sbjct 5673 VAYIAPTHKLVQSMDQAIWDKYNHTVSVSVVKSELNNNKYN-YPLNSATKTIMLGTPGAV 5731
Query 5665 PETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFN 5724
++FDE++++ + + ++ +++GDP QL P T + +L Y N
Sbjct 5732 CTHAGCTLIFDEVTLSQLNTIINAISVVKPSQVIFLGDPLQL-GPVTHMR--SLSYSYTN 5788
Query 5725 SVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHD 5784
L + L C RCP+ I ++ +K + D + + G
Sbjct 5789 --FPLFQFCNDSRVLSICYRCPSNI--------FNLWVKPYTDSNVRIDPHAAGGDAKII 5838
Query 5785 VSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQ-TVDSSQGSEYD 5843
VS + P + L RN + V + Y I+GL T+DSSQG Y
Sbjct 5839 VSDQCSNPDAYQYVQKLARNNPDK--VLLCNYK------KPIIGLENAVTIDSSQGKTYK 5890
Query 5844 YVIFTQTTETAHSCNVNRFNVAITRAKIGI 5873
+ I T + +NR VA++R+ I
Sbjct 5891 HTIVVLLGNTNFTQVINRAIVAMSRSTHSI 5920
Score = 110 bits (274), Expect = 8e-22, Method: Composition-based stats.
Identities = 38/112 (34%), Positives = 56/112 (50%), Gaps = 12/112 (11%)
Query 6081 DRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDKRATCFSTSSDTYACW-NHSVGFDY-- 6137
+RVV+VL+ G +L ++ +G + TC C K AT ++ + + NH +
Sbjct 6074 NRVVYVLYGAGNDLRALTNLNIVG-DYTCEKCTKEATFYTIHREIVHTFCNHHAPSQFPL 6132
Query 6138 --VYNPFMIDVQQWGFTGNLQSNHDQHCQV----HGNAHVASCDAIMTRCLA 6183
N ID+Q + N QS + H +V HG+AH AS D IMT CLA
Sbjct 6133 MGTINAQAIDIQHA--SANKQSLTNTHAEVCNQQHGDAHTASADTIMTGCLA 6182
Score = 56.2 bits (134), Expect = 2e-05, Method: Composition-based stats.
Identities = 119/804 (15%), Positives = 242/804 (30%), Gaps = 120/804 (15%)
Query 2998 VDAMNLIANIFTPLVQPVGALDVSASVVAGGII---AILVTCAAYYFMKFRRVFGEYNHV 3054
+ L + + V+ L AS ++ ++++ +Y + +F Y +
Sbjct 3219 SNTKKLCVQVGSNAVRCASVLPTGASSNVAALLMASVVVISMVLFYLYLLQ-IFKFYTNS 3277
Query 3055 VAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVP 3114
V + ++ L++ + + ++ + Y Y +++ + ++
Sbjct 3278 VIMSFVIQLLTLLATTVSTPLAVTVQLFVITYGY--------TNWILLTLSLLNLTVLLS 3329
Query 3115 FWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTF---STFEEAALCTFLLNKEMYLKLR 3171
+ +V L + F + + V G T +FE+ A TF L ++L
Sbjct 3330 TPVGITFVVIYGLYKAYTLFTSSGQGCVYNEGGTIRFSGSFEQVANSTFPLTNASCVQLL 3389
Query 3172 SETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQ 3231
S+ + Q N Y + ++ + R A L + L+ S +LY+
Sbjct 3390 SDLGITYQQLNVYASSRDR-----------NVRRLAQALLHRQLDSASEC---ILYE--G 3433
Query 3232 TSITSAVLQSGFRKMAFPSGKVEGCMVQVT-CGTTTLNGLWLD---------DTVYCPRH 3281
S + Q+ R + V + + NG+ L + + C H
Sbjct 3434 CSGNTITRQALQRIRQAVTVVVTPASQNLCKITSNQANGIGLSCTGTFFTSTEIITCA-H 3492
Query 3282 VICTAEDML---NPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKT 3338
I T++ Y+ + +N ++ V L V + + + +
Sbjct 3493 GIGTSDITAVHKGITYDCKVKSINNDIAILITTTVNLSVQNIKLDSSFSQKSDNYQRNFV 3552
Query 3339 PKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVS 3398
FV Q ++ + H G GS + ++ + +
Sbjct 3553 QFVSFVDQQNSDAVTINN----------TVMLPSGHFFAIGTEAGESGSP-YTLNGNII- 3600
Query 3399 FCYMHHMELPTGVHAGTDLEGKFY------GPFVDRQTAQAAGTDTTITLNVLAWLYAAV 3452
G+H G D G + G F T T + + A + A+
Sbjct 3601 -----------GIHYGIDNAGSWMLASRPDGSFYVPATQHGNSAKVTFSTDAFAQQFPAI 3649
Query 3453 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELL 3512
+ T+ N +A N D D V + LK L
Sbjct 3650 V--------TNKTSDQLVNEIAATNN-TAFELDTTD------------VSHLSNLLKHLK 3688
Query 3513 QNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILV 3572
N + L D V +Q S VT V + L S +I
Sbjct 3689 NNNETPK------SLSDYLPVAPVTQQTS-VTVGQTLTSPVNNMQTALYTLMLVSEVITY 3741
Query 3573 QSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYM 3632
T N+ L + + +A K + L ++ T + +
Sbjct 3742 ILT---------PNSDLSVLISMFVTSAFLKFGAS-KLFYNTEMLRNTITTFVVYRYTTL 3791
Query 3633 PASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVI 3692
+ V L+ + + + L+L+T R VY + + + + +I
Sbjct 3792 LIALVFSQYYLHILSYALKLNTLVLTVIALTFLVTPLVLLTIRRVYYYSQNYLISCVFII 3851
Query 3693 TLV--YKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
+ + D + +IS + + + I F + P
Sbjct 3852 SCFASHTYTLYILTDTTVDFQTFIIS------EPIFSTLLCNLFIGFTLISVVPNPLYVC 3905
Query 3751 NTLQCIMLVYCFLGYCCCCYFGLF 3774
I+L LG+ C+ +
Sbjct 3906 VVFMYILLDCEALGFIVTCFMASY 3929
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 42/200 (21%), Positives = 61/200 (31%), Gaps = 37/200 (19%)
Query 1004 NQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAM-- 1061
N F + V +I + IVNAAN L +G GV GA+ A + +
Sbjct 1642 NPFAS----NEGVTFAVHNIGAITTTEGE-FIVNAANKQLNNGTGVTGAIFAAHDKELKL 1696
Query 1062 ---------QKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPN------------- 1099
SD + + A LH P
Sbjct 1697 TQAIKALPTYGASDKLESHQHVVQT--IIKNNNSTHAINILHAAAPIKVKCTSKNPEVLL 1754
Query 1100 -LNAGEDIQLLKAA-----YENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYI 1153
N +L + Y N + PL AG +G KPL SL+ + +R +
Sbjct 1755 AHNETAQSELKETYKAIVDYAQLNKLTHIYLPLFGAGAYGHKPLDSLEAFLDAMRNRSPQ 1814
Query 1154 AVNDKALYEQVVMDYLDNLK 1173
+ L + LDN
Sbjct 1815 STTQYTLLLSDPVKPLDNPS 1834
Score = 39.3 bits (90), Expect = 2.0, Method: Composition-based stats.
Identities = 52/341 (15%), Positives = 91/341 (27%), Gaps = 59/341 (17%)
Query 2110 VPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKST--NSRI 2167
+S LAY+ + Y+ T T+ T + I
Sbjct 2551 CTFSVFLAYIALLYSFSGHGIFTVVAYFTMLFARYYITSFINFCTSQLTATQVTQWFAAI 2610
Query 2168 RASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAF 2227
+A + + + + Y+ K+S + T+ M++ ++
Sbjct 2611 KAKYTGIYESSQDRVLTVNVTGTNVPYI--VKYSTILTVTMYVAFMAFVWTVSTYAAQYT 2668
Query 2228 G-----------VLLSNFGAPSYCNGVRELYLNSSNVTTMDFCE--GSFPCSI-CLSGLD 2273
V V Y +S + C S C +
Sbjct 2669 AGERYDRPPYQTVFQKTLNVLGLTETVTYYYPYAS---LNEACAASTSILCRLGSPFNFH 2725
Query 2274 SLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFAS 2333
Y + T+Q SS + LF F L ++ +
Sbjct 2726 YPSDYTQVRTVQTDTSS----------------PFWLFIIFMPPSFLFIVLPWLILCTIT 2769
Query 2334 HFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRN 2393
+SI Q+ S ++ I F Y K H C TC+ +
Sbjct 2770 P----------TVSIAQLLVPSIILNATIVF--IYIRRKFTGHC---CGPHTCIKHADIS 2814
Query 2394 RATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDT 2434
R+ + T+ + C HNW C N D+
Sbjct 2815 RSLQFRPTSQIQHSLTFC-------GTLCAKHNWYCNNSDS 2848
>sp|Q9WQ77|R1AB_CVRSD Replicase polyprotein 1ab (Fragment) OS=Rat
coronavirus (strain 681) OX=33740 GN=rep PE=3 SV=1
Length=307
Score = 511 bits (1315), Expect = 2e-163, Method: Composition-based stats.
Identities = 224/307 (73%), Positives = 266/307 (87%), Gaps = 0/307 (0%)
Query 4875 FNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICST 4934
FNK+GKARLYY+++S+E+QD ++AYTKRNV+PT+TQMNLKYAISAKNRARTVAGVSI ST
Sbjct 1 FNKFGKARLYYEALSFEEQDEIYAYTKRNVLPTLTQMNLKYAISAKNRARTVAGVSILST 60
Query 4935 MTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRA 4994
MT R FHQK LKSIAATRG VVIGT+KFYGGW +ML+ + DV++P LMGWDYPKCDRA
Sbjct 61 MTGRMFHQKCLKSIAATRGVPVVIGTTKFYGGWDDMLRRLIKDVDSPVLMGWDYPKCDRA 120
Query 4995 MPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDA 5054
MPN+LRI++SLVLARKH++CC+ + RFYRLANECAQVLSE+VMCGG YVKPGGTSSGDA
Sbjct 121 MPNILRIVSSLVLARKHDSCCSHTDRFYRLANECAQVLSEIVMCGGCYYVKPGGTSSGDA 180
Query 5055 TTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEF 5114
TTA+ANSVFNICQAV+ANV +L++ +G+KI D +R LQ RLY +YR VD FV E+
Sbjct 181 TTAFANSVFNICQAVSANVCSLMACNGHKIEDLSIRELQKRLYSNVYRADHVDPAFVSEY 240
Query 5115 YAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDL 5174
Y +L KHFSMMILSDD VVCYNS +A++G +A+I F+ VLYYQNNVFMSEAKCW ETD+
Sbjct 241 YEFLNKHFSMMILSDDGVVCYNSEFASKGYIANISAFQQVLYYQNNVFMSEAKCWVETDI 300
Query 5175 TKGPHEF 5181
KGPHEF
Sbjct 301 EKGPHEF 307
>sp|Q9WQ76|R1AB_CVTMI Replicase polyprotein 1ab (Fragment) OS=Turkey
coronavirus (strain Minnesota) OX=231430 GN=rep PE=3
SV=1
Length=306
Score = 480 bits (1236), Expect = 8e-153, Method: Composition-based stats.
Identities = 212/307 (69%), Positives = 245/307 (80%), Gaps = 1/307 (0%)
Query 4875 FNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICST 4934
FNK+GKARLYY+ MS E+QD LF TK+NV+PTITQMNLKYAISAKNRARTVAGVSI ST
Sbjct 1 FNKFGKARLYYE-MSLEEQDQLFESTKKNVLPTITQMNLKYAISAKNRARTVAGVSILST 59
Query 4935 MTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRA 4994
MTNRQFHQK+LKSI TR A VVIGT+KFYGGW NML+ + VE P LMGWDYPKCDRA
Sbjct 60 MTNRQFHQKILKSIVNTRNAPVVIGTTKFYGGWDNMLRNLIQGVEDPILMGWDYPKCDRA 119
Query 4995 MPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDA 5054
MPN+LRI ASLVLARKH CC S R YRL NECAQVLSE V+ G +YVKPGGTSSGDA
Sbjct 120 MPNLLRITASLVLARKHTNCCTWSERIYRLYNECAQVLSETVLATGGIYVKPGGTSSGDA 179
Query 5055 TTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEF 5114
TTAYANSVFNI QA +ANV LLS I +++LQ+ LY+ +YR + D FV++F
Sbjct 180 TTAYANSVFNIIQATSANVARLLSVITRDIVYDDIKSLQYELYQQVYRRVNFDPAFVEKF 239
Query 5115 YAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDL 5174
Y+YL K+FS+MI +DD VVCYN+ A QGLVA I F+ +LYYQNNV+M+++KCW E DL
Sbjct 240 YSYLCKNFSLMIFADDGVVCYNNTLAKQGLVADISGFREILYYQNNVYMADSKCWVEPDL 299
Query 5175 TKGPHEF 5181
KGPHEF
Sbjct 300 EKGPHEF 306
>sp|P36697|R1AB_CVCAI Replicase polyprotein 1ab (Fragment) OS=Canine
coronavirus (strain Insavc-1) OX=36391 GN=rep PE=4 SV=1
Length=168
Score = 268 bits (684), Expect = 1e-80, Method: Composition-based stats.
Identities = 87/166 (52%), Positives = 117/166 (70%), Gaps = 2/166 (1%)
Query 6909 PRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKLMGHFSWWTAF 6968
P TK + EN SK+GFFTY+ GFIK+KL+LGGS A+KITE SWN DLY+L+ F +WT F
Sbjct 1 PNTKSIDGENTSKDGFFTYVNGFIKEKLSLGGSAAIKITEFSWNKDLYELIQRFEYWTVF 60
Query 6969 VTNVNASSSEAFLIGANYLGK--PKEQIDGYTMHANYIFWRNTNPIQLSSYSLFDMSKFP 7026
T+VN SSSE FLIG NYLG + +DG MHANYIFWRN+ + LS S+ D KF
Sbjct 61 CTSVNTSSSEGFLIGVNYLGPYCDRAIVDGNIMHANYIFWRNSTIMALSHNSVLDTPKFK 120
Query 7027 LKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDILVN 7072
+ +++LKE ++N+M+ LL+KG+L+IR N +++ + LVN
Sbjct 121 CRCNNALIVNLKEKELNEMVIGLLKKGKLLIRNNGKLLNFGNHLVN 166
>sp|Q04158|R1AB_CVPR8 Replicase polyprotein 1ab (Fragment) OS=Porcine
respiratory coronavirus (strain 86/137004 / isolate
British) OX=33736 GN=rep PE=4 SV=1
Length=131
Score = 212 bits (540), Expect = 6e-62, Method: Composition-based stats.
Identities = 61/130 (47%), Positives = 84/130 (65%), Gaps = 2/130 (2%)
Query 6946 ITEHSWNADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGK--PKEQIDGYTMHANY 7003
ITE SWN LY+L+ F +WT F T+VN SSSE FLIG NYLG K +DG MHANY
Sbjct 1 ITEFSWNKYLYELIQRFEYWTVFCTSVNTSSSEGFLIGVNYLGPYCDKAIVDGNIMHANY 60
Query 7004 IFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRV 7063
IFWRN+ + LS S+ D KF + +++LKE ++N+M+ LL KG+L+IR N ++
Sbjct 61 IFWRNSTIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVIGLLRKGKLLIRNNGKL 120
Query 7064 VVSSDILVNN 7073
+ + +N
Sbjct 121 LNFGNHFINT 130
>sp|Q8GYD9|SDE3_ARATH Probable RNA helicase SDE3 OS=Arabidopsis
thaliana OX=3702 GN=SDE3 PE=1 SV=1
Length=1002
Score = 236 bits (601), Expect = 2e-61, Method: Composition-based stats.
Identities = 98/388 (25%), Positives = 142/388 (37%), Gaps = 100/388 (26%)
Query 5581 LQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAAVDALCEKAL----------KYL 5626
+ GPPGTGK+ + L +AR++ A S++A D + EK L +
Sbjct 419 IHGPPGTGKTMTLVEAIVQLYTTQRNARVLVCAPSNSAADHILEKLLCLEGVRIKDNEIF 478
Query 5627 PIDKCSR----IIPARARVECFDK--FK------------VNSTLEQYVFCTVNALPETT 5668
++ +R I P R FD+ FK V ST +
Sbjct 479 RLNAATRSYEEIKPEIIRFCFFDELIFKCPPLKALTRYKLVVSTYMSASLLNAEGVNRGH 538
Query 5669 ADIVVFDEISMATNYD--LSVVNARLRAKHYVYIGDPAQL-------PAPRTLLTKGTLE 5719
++ DE A+ + ++V N L V GDP QL A L K LE
Sbjct 539 FTHILLDEAGQASEPENMIAVSNLCLTETVVVLAGDPRQLGPVIYSRDAESLGLGKSYLE 598
Query 5720 P----EYF-----NSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSA 5770
+Y+ N V +L+K RC EI+D S L YD +L A K+ +
Sbjct 599 RLFECDYYCEGDENYVTKLVKN----------YRCHPEILDLPSKLFYDGELVASKEDTD 648
Query 5771 QC-----------FKMFYKGVITHDVS-----SAINRPQIGVVREFLTRNPA-----WRK 5809
F M + G+ D S NR +I V E + R A
Sbjct 649 SVLASLNFLPNKEFPMVFYGIQGCDEREGNNPSWFNRIEISKVIETIKRLTANDCVQEED 708
Query 5810 AVFISPYNSQNAVASKILG------LPTQTVDSSQGSEYDYVIFTQTTET---------- 5853
I+PY Q ++L + +V+ QG E +I + T
Sbjct 709 IGVITPYRQQVMKIKEVLDRLDMTEVKVGSVEQFQGQEKQVIIISTVRSTIKHNEFDRAY 768
Query 5854 --AHSCNVNRFNVAITRAKIGILCIMSD 5879
N RFNVAITRA I +L I+ +
Sbjct 769 CLGFLSNPRRFNVAITRA-ISLLVIIGN 795
>sp|P38859|DNA2_YEAST DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Saccharomyces cerevisiae (strain ATCC 204508
/ S288c) OX=559292 GN=DNA2 PE=1 SV=1
Length=1522
Score = 196 bits (499), Expect = 3e-48, Method: Composition-based stats.
Identities = 85/384 (22%), Positives = 135/384 (35%), Gaps = 82/384 (21%)
Query 5576 QKYSTLQGPPGTGKSHFA--IGLALYYPSARIVYTACSHAAVDALCEK-----------A 5622
+ Y+ + G PGTGK+ I L R++ T+ +H+AVD + K
Sbjct 1067 EDYALILGMPGTGKTTVIAEIIKILVSEGKRVLLTSYTHSAVDNILIKLRNTNISIMRLG 1126
Query 5623 LKYLPIDKCSRIIPARARVECFDKF--KVNSTLEQYVFCT-VN----ALPETTADIVVFD 5675
+K+ + +P A V+ ++ + K+NST C +N L E D V+ D
Sbjct 1127 MKHKVHPDTQKYVPNYASVKSYNDYLSKINSTSVVATTCLGINDILFTLNEKDFDYVILD 1186
Query 5676 EISMATNYDLSVVNARLRA-KHYVYIGDPAQLPA--PRTLLTKGTLEPEYFNSVCRLMKT 5732
E S + + V LR ++ +GD QLP G LE F + C
Sbjct 1187 EASQIS---MPVALGPLRYGNRFIMVGDHYQLPPLVKNDAARLGGLEESLFKTFCEKHPE 1243
Query 5733 IGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDK-----------------------S 5769
++ L R +IV + L+YDNKLK ++ S
Sbjct 1244 SVAELTL--QYRMCGDIVTLSNFLIYDNKLKCGNNEVFAQSLELPMPEALSRYRNESANS 1301
Query 5770 AQCFKMFYKGVITHDVSSAINRPQI-------------------GVVREFLTRNPAWRKA 5810
Q + + + N P I V L
Sbjct 1302 KQWLEDILEPTRKVVFLNYDNCPDIIEQSEKDNITNHGEAELTLQCVEGMLLSGVPCEDI 1361
Query 5811 VFISPYNSQNAVASKIL------GLPTQTVDSSQGSEYDYVIFTQTTETAHSC------N 5858
++ Y +Q + KI GL T D QG + +I + +
Sbjct 1362 GVMTLYRAQLRLLKKIFNKNVYDGLEILTADQFQGRDKKCIIISMVRRNSQLNGGALLKE 1421
Query 5859 VNRFNVAITRAKIGILCIMSDRDL 5882
+ R NVA+TRAK ++ I S +
Sbjct 1422 LRRVNVAMTRAKSKLIIIGSKSTI 1445
>sp|B6SFA4|MAA3_ARATH Probable helicase MAGATAMA 3 OS=Arabidopsis
thaliana OX=3702 GN=MAA3 PE=2 SV=1
Length=818
Score = 189 bits (481), Expect = 3e-47, Method: Composition-based stats.
Identities = 86/364 (24%), Positives = 129/364 (35%), Gaps = 90/364 (25%)
Query 5604 RIVYTACSHAAVDALCEKALKY-LPIDKCSRIIPARARV--------------------- 5641
R++ A S++A+D + + L L + P R+
Sbjct 376 RVLVCAPSNSALDEIVLRLLSSGLRDENAQTYTPKIVRIGLKAHHSVASVSLDHLVAQKR 435
Query 5642 -ECFDKFKVNSTL-------------EQYVFCTVN-------ALPETTADIVVFDEISMA 5680
DK K +T VF T++ A D+V+ DE + A
Sbjct 436 GSAIDKPKQGTTGTDIDSIRTAILEEAAIVFATLSFSGSALLAKSNRGFDVVIIDEAAQA 495
Query 5681 TNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC-RLMKTIGPDMFL 5739
+++ R K +GDP QLPA T+++ + Y S+ RL K P L
Sbjct 496 VEP-ATLIPLATRCKQVFLVGDPKQLPA--TVISTVAQDSGYGTSMFERLQKAGYPVKML 552
Query 5740 GTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ--------------CFKMFYKGVITHD- 5784
T R EI S Y+ L+ D AQ CF ++G +
Sbjct 553 KTQYRMHPEIRSFPSKQFYEGALEDGSDIEAQTTRDWHKYRCFGPFCFFDIHEGKESQHP 612
Query 5785 --VSSAINRPQIGVV----REFLTRNPAWRKA---VFISPYNSQ------------NAVA 5823
S +N ++ V +T P + + ISPYN Q A
Sbjct 613 GATGSRVNLDEVEFVLLIYHRLVTMYPELKSSSQLAIISPYNYQVKTFKDRFKEMFGTEA 672
Query 5824 SKILGLPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAITRAKIGILCIMS 5878
K++ + TVD QG E D IF+ + + N R NV ITRAK +L + S
Sbjct 673 EKVVDI--NTVDGFQGREKDVAIFSCVRANENGQIGFLSNSRRMNVGITRAKSSVLVVGS 730
Query 5879 DRDL 5882
L
Sbjct 731 AATL 734
>sp|B5F961|YMDB_SALA4 O-acetyl-ADP-ribose deacetylase OS=Salmonella
agona (strain SL483) OX=454166 GN=ymdB PE=3 SV=1
Length=179
Score = 160 bits (405), Expect = 5e-43, Method: Composition-based stats.
Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 17/176 (10%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T + + DI + + IVNAAN L GGGV GA+++A A+ +
Sbjct 1 MTSRLQVIQGDITQLS----VDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1072 NGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENF------NSQDIL 1122
G G + + L AK +H VGP GE + +LL+AAY N N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEYQEAELLEAAYRNCLLLAEANHFRSI 116
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
P +S G++G Q+ +V V+TV + AL EQV D R+ A
Sbjct 117 AFPAISTGVYGYPRAQAAEVAVRTVSD----FITRYALPEQVYFVCYDEETARLYA 168
>sp|B4T2X8|YMDB_SALNS O-acetyl-ADP-ribose deacetylase OS=Salmonella
newport (strain SL254) OX=423368 GN=ymdB PE=3 SV=1
Length=179
Score = 160 bits (405), Expect = 6e-43, Method: Composition-based stats.
Identities = 51/176 (29%), Positives = 77/176 (44%), Gaps = 17/176 (10%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T + + DI + + IVNAAN L GGGV GA+++A A+ +
Sbjct 1 MTSRLQVIQGDITQLS----VDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1072 NGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENF------NSQDIL 1122
G G + + L AK +H VGP GE + +LL+ AY N N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRNCLLLAEANHFRSI 116
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
P +S G++G Q+ ++ V+TV + AL EQV D R+ A
Sbjct 117 AFPAISTGVYGYPRAQAAEIAVRTVSD----FITRYALPEQVYFVCYDEETARLYA 168
>sp|P67341|YMDB_SALTY O-acetyl-ADP-ribose deacetylase OS=Salmonella
typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287
GN=ymdB PE=3 SV=1
Length=179
Score = 160 bits (404), Expect = 8e-43, Method: Composition-based stats.
Identities = 52/176 (30%), Positives = 77/176 (44%), Gaps = 17/176 (10%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T + + DI + + IVNAAN L GGGV GA+++A A+ +
Sbjct 1 MTSRLQVIQGDITQLS----VDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1072 NGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENF------NSQDIL 1122
G G + + L AK +H VGP GE + +LL+ AY N N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRNCLLLAEANHFRSI 116
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
P +S G++G Q+ +V V+TV + AL EQV D R+ A
Sbjct 117 AFPAISTGVYGYPRAQAAEVAVRTVSD----FITRYALPEQVYFVCYDEETARLYA 168
>sp|P67342|YMDB_SALTI O-acetyl-ADP-ribose deacetylase OS=Salmonella
typhi OX=90370 GN=ymdB PE=3 SV=1
Length=179
Score = 160 bits (404), Expect = 8e-43, Method: Composition-based stats.
Identities = 52/176 (30%), Positives = 77/176 (44%), Gaps = 17/176 (10%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T + + DI + + IVNAAN L GGGV GA+++A A+ +
Sbjct 1 MTSRLQVIQGDITQLS----VDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1072 NGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENF------NSQDIL 1122
G G + + L AK +H VGP GE + +LL+ AY N N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRNCLLLAEANHFRSI 116
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
P +S G++G Q+ +V V+TV + AL EQV D R+ A
Sbjct 117 AFPAISTGVYGYPRAQAAEVAVRTVSD----FITRYALPEQVYFVCYDEETARLYA 168
>sp|A7MG20|YMDB_CROS8 O-acetyl-ADP-ribose deacetylase OS=Cronobacter
sakazakii (strain ATCC BAA-894) OX=290339 GN=ymdB PE=3
SV=1
Length=180
Score = 159 bits (403), Expect = 9e-43, Method: Composition-based stats.
Identities = 50/184 (27%), Positives = 78/184 (42%), Gaps = 25/184 (14%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
++ + + DI + VIVNAAN L GGGV GA+++A A+ +
Sbjct 1 MSGRINVVQGDIT----LIDVDVIVNAANPSLMGGGGVDGAIHRAAGPALLAACRQVRQQ 56
Query 1072 NGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAG--EDIQLLKAAYEN------FNSQDIL 1122
G G + + +L AK +H VGP G + QLL AY N N + +
Sbjct 57 QGECQPGHAVITEAGDLAAKAVVHTVGPVWRGGQDNEPQLLADAYRNSLQLVAANGYNSV 116
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTV---------RTQVYIAVNDKA---LYEQVVMDYLD 1170
P +S GI+G + Q+ +TV QVY D+ LY++++ Y +
Sbjct 117 AFPAISTGIYGYPKAAAAQIAFETVSDYLTRHPQPKQVYFVCYDEENFLLYQRLLGQYDE 176
Query 1171 NLKP 1174
Sbjct 177 QPGA 180
>sp|B5RBF3|YMDB_SALG2 O-acetyl-ADP-ribose deacetylase OS=Salmonella
gallinarum (strain 287/91 / NCTC 13346) OX=550538 GN=ymdB
PE=3 SV=1
Length=179
Score = 158 bits (400), Expect = 2e-42, Method: Composition-based stats.
Identities = 51/176 (29%), Positives = 77/176 (44%), Gaps = 17/176 (10%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+T + + DI + + IVNAAN L GGGV GA+++A A+ +
Sbjct 1 MTSRLQVIQGDITQLS----VDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQ 56
Query 1072 NGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENF------NSQDIL 1122
G G + + L AK +H VGP GE + +LL+ AY + N +
Sbjct 57 QGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRSCLLLAEANHFRSI 116
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
P +S G++G Q+ +V V+TV + AL EQV D R+ A
Sbjct 117 AFPAISTGVYGYPRAQAAEVAVRTVSD----FITRYALPEQVYFVCYDEETARLYA 168
>sp|D5CE05|YMDB_ENTCC O-acetyl-ADP-ribose deacetylase OS=Enterobacter
cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054
/ NBRC 13535 / NCTC 10005 / WDCM 00083 / NCDC 279-56) OX=716541
GN=ymdB PE=3 SV=1
Length=180
Score = 158 bits (400), Expect = 2e-42, Method: Composition-based stats.
Identities = 43/165 (26%), Positives = 74/165 (45%), Gaps = 14/165 (8%)
Query 1019 KCVDIVK-EAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+D++ + + + VIVNAAN L GGGV GA+++A + + + G
Sbjct 3 PQIDVIHGDITTMHVDVIVNAANPSLMGGGGVDGAIHRAAGPQLLEACKTVRQQQGECPP 62
Query 1078 GGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENF------NSQDILLAPLLS 1128
G + + +L AK +H VGP + G+ + +L+ AY N N + P +S
Sbjct 63 GHAVITLAGDLPAKAVIHAVGPIWHGGDRHEASILEEAYRNCLRLAADNGYKTMAFPAIS 122
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLK 1173
G++G + + V T VY ++ K + E+V D
Sbjct 123 TGVYGYPKAAAATIAVDT----VYRYLSLKPMPEKVTFVCFDEET 163
>sp|C9Y0V8|YMDB_CROTZ O-acetyl-ADP-ribose deacetylase OS=Cronobacter
turicensis (strain DSM 18703 / CCUG 55852 / LMG 23827
/ z3032) OX=693216 GN=ymdB PE=3 SV=1
Length=176
Score = 158 bits (399), Expect = 3e-42, Method: Composition-based stats.
Identities = 49/180 (27%), Positives = 79/180 (44%), Gaps = 25/180 (14%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
++ + + DI + + VIVNAAN L GGGV GA+++A ++ +
Sbjct 1 MSGRINVVQGDITRI----DTDVIVNAANPSLMGGGGVDGAIHRAAGPSLLAACKVVRQQ 56
Query 1072 NGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAG--EDIQLLKAAYEN------FNSQDIL 1122
G G + + +L AK +H VGP G + QLL AY N N + +
Sbjct 57 QGECQPGHAVITEAGDLAAKAVIHTVGPIWRGGHDNEPQLLADAYRNSLELVTANGYNSV 116
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTV---------RTQVYIAVNDKA---LYEQVVMDYLD 1170
P +S GI+G + Q+ +TV QVY D+ LY++++ Y +
Sbjct 117 AFPAISTGIYGYPKAAAAQIAFETVSDYLTRRPQPKQVYFVCYDEENFLLYQRLLGQYDE 176
>sp|A4W960|YMDB_ENT38 O-acetyl-ADP-ribose deacetylase OS=Enterobacter
sp. (strain 638) OX=399742 GN=ymdB PE=3 SV=1
Length=180
Score = 158 bits (400), Expect = 3e-42, Method: Composition-based stats.
Identities = 46/176 (26%), Positives = 72/176 (41%), Gaps = 17/176 (10%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ + + DI VIVNAAN L GGGV GA+++A + + +
Sbjct 1 MKPQIEVVVGDITTME----VDVIVNAANPSLMGGGGVDGAIHRAAGPQLLEACKTVRQQ 56
Query 1072 NGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQ--LLKAAYENF------NSQDIL 1122
G G + + +L AK +H VGP GE+ + L+ AY N N L
Sbjct 57 QGECAPGHAVITIAGDLPAKAVIHAVGPVWQGGENHEARTLQDAYLNCLRLAAANGYKTL 116
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
P +S G++G + ++ V TV + K L E+V D ++
Sbjct 117 AFPAISTGVYGYPKAAAAEIAVDTVSE----FLTRKPLPERVYFVCYDEENAQLYQ 168
>sp|P0A8D6|YMDB_ECOLI O-acetyl-ADP-ribose deacetylase OS=Escherichia
coli (strain K12) OX=83333 GN=ymdB PE=1 SV=1
Length=177
Score = 158 bits (399), Expect = 3e-42, Method: Composition-based stats.
Identities = 52/169 (31%), Positives = 74/169 (44%), Gaps = 17/169 (10%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ DI K A VIVNAAN L GGGV GA+++A A+ + G
Sbjct 7 VVQGDITKLA----VDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPT 62
Query 1078 GGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLS 1128
G + + +L AK +H VGP GE + QLL+ AY N NS + P +S
Sbjct 63 GHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAIS 122
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVE 1177
G++G + ++ V+TV + AL EQV D +
Sbjct 123 TGVYGYPRAAAAEIAVKTVSE----FITRHALPEQVYFVCYDEENAHLY 167
>sp|P0A8D7|YMDB_ECOL6 O-acetyl-ADP-ribose deacetylase OS=Escherichia
coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) OX=199310
GN=ymdB PE=3 SV=1
Length=177
Score = 158 bits (399), Expect = 3e-42, Method: Composition-based stats.
Identities = 52/169 (31%), Positives = 74/169 (44%), Gaps = 17/169 (10%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ DI K A VIVNAAN L GGGV GA+++A A+ + G
Sbjct 7 VVQGDITKLA----VDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPT 62
Query 1078 GGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLS 1128
G + + +L AK +H VGP GE + QLL+ AY N NS + P +S
Sbjct 63 GHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAIS 122
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVE 1177
G++G + ++ V+TV + AL EQV D +
Sbjct 123 TGVYGYPRAAAAEIAVKTVSE----FITRHALPEQVYFVCYDEENAHLY 167
>sp|P0A8D8|YMDB_ECO57 O-acetyl-ADP-ribose deacetylase OS=Escherichia
coli O157:H7 OX=83334 GN=ymdB PE=3 SV=1
Length=177
Score = 158 bits (399), Expect = 3e-42, Method: Composition-based stats.
Identities = 52/169 (31%), Positives = 74/169 (44%), Gaps = 17/169 (10%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ DI K A VIVNAAN L GGGV GA+++A A+ + G
Sbjct 7 VVQGDITKLA----VDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPT 62
Query 1078 GGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLS 1128
G + + +L AK +H VGP GE + QLL+ AY N NS + P +S
Sbjct 63 GHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAIS 122
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVE 1177
G++G + ++ V+TV + AL EQV D +
Sbjct 123 TGVYGYPRAAAAEIAVKTVSE----FITRHALPEQVYFVCYDEENAHLY 167
>sp|B7LT90|YMDB_ESCF3 O-acetyl-ADP-ribose deacetylase OS=Escherichia
fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766
/ IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128
/ CDC 0568-73) OX=585054 GN=ymdB PE=3 SV=2
Length=177
Score = 157 bits (397), Expect = 5e-42, Method: Composition-based stats.
Identities = 49/170 (29%), Positives = 73/170 (43%), Gaps = 17/170 (10%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ DI + A VIVNAAN L GGGV GA+++A + + + G
Sbjct 7 VLQGDITQLA----VDVIVNAANSSLMGGGGVDGAIHRAAGPELLEACQKVRRQQGECPT 62
Query 1078 GGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLS 1128
G + + NL A+ +H VGP GE + QLL AY N N + P +S
Sbjct 63 GHAVITIAGNLPARAVIHTVGPVWRDGEHNEDQLLHDAYLNSLKLAQANGYKSIAFPAIS 122
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
G++G + ++ V+TV + AL EQ+ D R+
Sbjct 123 TGVYGFPRAAAAEIAVKTVSD----FITRHALPEQIYFVCYDEENSRLYN 168
>sp|Q0T5Z6|YMDB_SHIF8 O-acetyl-ADP-ribose deacetylase OS=Shigella
flexneri serotype 5b (strain 8401) OX=373384 GN=ymdB PE=3
SV=1
Length=177
Score = 156 bits (395), Expect = 1e-41, Method: Composition-based stats.
Identities = 51/169 (30%), Positives = 73/169 (43%), Gaps = 17/169 (10%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ DI K A VIVNAAN L GGGV GA+++A A+ + G
Sbjct 7 VVQGDITKLA----VDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPT 62
Query 1078 GGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLS 1128
G + + +L AK +H VGP GE + QLL+ AY N NS + P +S
Sbjct 63 GHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAIS 122
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVE 1177
G++ + ++ V+TV + AL EQV D +
Sbjct 123 TGVYSYPRAAAAEIAVKTVSE----FITRHALPEQVYFVCYDEENAHLY 167
>sp|D2TT52|YMDB_CITRI O-acetyl-ADP-ribose deacetylase OS=Citrobacter
rodentium (strain ICC168) OX=637910 GN=ymdB PE=3 SV=2
Length=177
Score = 155 bits (393), Expect = 2e-41, Method: Composition-based stats.
Identities = 43/162 (27%), Positives = 68/162 (42%), Gaps = 13/162 (8%)
Query 1026 EAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSG 1085
+ + IVNAAN L GGGV GA+++A + + + G G + + +
Sbjct 11 DITTVAVDAIVNAANPSLMGGGGVDGAIHRAAGPELLEACMTVRRQQGECPPGHAVITAA 70
Query 1086 HNL-AKKCLHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLSAGIFGAKP 1136
L AK +H VGP GE + QLL AY N N + P +S G++G
Sbjct 71 GRLPAKAVIHTVGPIWRGGEHNEAQLLHDAYLNSLNLALANGYQSIAFPAISTGVYGYPR 130
Query 1137 LQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
+ ++ V T+ + +A EQ+ D R+
Sbjct 131 AAAAEIAVNTISE----FITRRASPEQIYFVCYDEETTRLYQ 168
>sp|A8AI35|YMDB_CITK8 O-acetyl-ADP-ribose deacetylase OS=Citrobacter
koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)
OX=290338 GN=ymdB PE=3 SV=1
Length=177
Score = 154 bits (390), Expect = 5e-41, Method: Composition-based stats.
Identities = 49/166 (30%), Positives = 69/166 (42%), Gaps = 17/166 (10%)
Query 1021 VDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGS 1080
DI + VIVNAAN L GGGV GA+++A + + + G G +
Sbjct 10 GDITQ----LTVDVIVNAANASLLGGGGVDGAIHRAAGPTLLEACKKVRQQQGECPAGHA 65
Query 1081 CLLSGHNL-AKKCLHVVGPNLNAG--EDIQLLKAAYEN------FNSQDILLAPLLSAGI 1131
+ NL AK +H VGP G + QLL+ AY N N + P +S G
Sbjct 66 VITLAGNLPAKAVIHTVGPVWRGGDHNESQLLEDAYFNSLQLVLANGYRSVAFPAISTGA 125
Query 1132 FGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVE 1177
+G + ++ V TV + AL EQV D R+
Sbjct 126 YGYPRPAAAEIAVNTVAD----FLARHALPEQVYFVCYDEETARLY 167
>sp|D3RKJ0|YMDB_KLEVT O-acetyl-ADP-ribose deacetylase OS=Klebsiella
variicola (strain At-22) OX=640131 GN=ymdB PE=3 SV=1
Length=175
Score = 154 bits (388), Expect = 9e-41, Method: Composition-based stats.
Identities = 42/164 (26%), Positives = 73/164 (45%), Gaps = 13/164 (8%)
Query 1023 IVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL 1082
I+ + + VIVNAAN L GGGV GA+++A A+ ++ G G + +
Sbjct 8 ILGDITTLEVDVIVNAANPSLLGGGGVDGAIHRAAGPALLAACKQVLQQQGECPPGHAVI 67
Query 1083 LSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLSAGIFG 1133
+L A +H VGP + G+ + Q L AY+N N+ + P +S G++G
Sbjct 68 TIAGDLPASAVIHTVGPVWHGGDRMEAQTLADAYKNSLQLAAANNYRSIAFPAISTGVYG 127
Query 1134 AKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVE 1177
++ ++ V+TV + E+V+ D +
Sbjct 128 YPKEEAAEIAVRTVTA----FLTRYNPLERVLFVCFDEETAAIY 167
>sp|B5XXK9|YMDB_KLEP3 O-acetyl-ADP-ribose deacetylase OS=Klebsiella
pneumoniae (strain 342) OX=507522 GN=ymdB PE=3 SV=1
Length=175
Score = 154 bits (388), Expect = 9e-41, Method: Composition-based stats.
Identities = 42/164 (26%), Positives = 73/164 (45%), Gaps = 13/164 (8%)
Query 1023 IVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL 1082
I+ + + VIVNAAN L GGGV GA+++A A+ ++ G G + +
Sbjct 8 ILGDITTLEVDVIVNAANPSLLGGGGVDGAIHRAAGPALLAACKQVLQQQGECPPGHAVI 67
Query 1083 LSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLSAGIFG 1133
+L A +H VGP + G+ + Q L AY+N N+ + P +S G++G
Sbjct 68 TIAGDLPASAVIHTVGPVWHGGDRMEAQTLADAYKNSLQLAAANNYRSIAFPAISTGVYG 127
Query 1134 AKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVE 1177
++ ++ V+TV + E+V+ D +
Sbjct 128 YPKEEAAEIAVRTVTA----FLTRYNPLERVLFVCFDEETAAIY 167
>sp|Q92355|SEN1_SCHPO Helicase sen1 OS=Schizosaccharomyces pombe
(strain 972 / ATCC 24843) OX=284812 GN=sen1 PE=1 SV=1
Length=1687
Score = 171 bits (432), Expect = 2e-40, Method: Composition-based stats.
Identities = 64/253 (25%), Positives = 102/253 (40%), Gaps = 41/253 (16%)
Query 5668 TADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC 5727
V+ DE + A D +++ R AK + +GDP QLP T+L+K Y S+
Sbjct 1371 NFSTVIIDEAAQAVELD-TIIPLRYGAKKCILVGDPNQLPP--TVLSKKAASLNYSQSLF 1427
Query 5728 -RLMKTIGPDM-FLGTCRRCPAEIVDTVSALVYDNKLKA------------HKDKSAQCF 5773
R+ K M L R +I S YD++L+ H + +
Sbjct 1428 VRIQKNFSNQMCLLSIQYRMHPDISHFPSKKFYDSRLEDGDNMAEKTQQVWHVNPKFTQY 1487
Query 5774 KMF-YKGV-ITHDVSSAINRPQIG----VVREFLTRNPAWR---KAVFISPYNSQNAVAS 5824
++F +G T + S N ++ +V E L + P + I+PY SQ
Sbjct 1488 RLFDVRGKERTSNTMSTYNLEEVEYLVNMVDELLNKFPDVNFTGRIGVITPYRSQLHELR 1547
Query 5825 K----------ILGLPTQTVDSSQGSEYDYVIF-TQTTETAHSC----NVNRFNVAITRA 5869
+ + + QTVD QG E D + F + + H + R NVA+TRA
Sbjct 1548 RAFKVKYGKSFMSTIDIQTVDGFQGQEKDIIFFSCVKSYSKHGIGFLRDFRRLNVALTRA 1607
Query 5870 KIGILCIMSDRDL 5882
+ +L I + L
Sbjct 1608 RSSLLIIGNMETL 1620
Score = 48.9 bits (115), Expect = 0.003, Method: Composition-based stats.
Identities = 20/84 (24%), Positives = 35/84 (42%), Gaps = 20/84 (24%)
Query 5578 YSTLQGPPGTGKSHFAIGLALY--------------------YPSARIVYTACSHAAVDA 5617
++ +QGPPGTGK+ IG+ +I+ A S+AAVD
Sbjct 1147 FTLIQGPPGTGKTKTIIGIISALLVDLSRYHITRPNQQSKSTESKQQILLCAPSNAAVDE 1206
Query 5618 LCEKALKYLPIDKCSRIIPARARV 5641
+ + + ++ + IP R+
Sbjct 1207 VLLRLKRGFLLENGEKYIPRVVRI 1230
>sp|Q32E73|YMDB_SHIDS O-acetyl-ADP-ribose deacetylase OS=Shigella
dysenteriae serotype 1 (strain Sd197) OX=300267 GN=ymdB
PE=3 SV=1
Length=177
Score = 152 bits (383), Expect = 4e-40, Method: Composition-based stats.
Identities = 50/169 (30%), Positives = 72/169 (43%), Gaps = 17/169 (10%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ DI K A VIVN N L GGGV GA+++A A+ + G
Sbjct 7 VVQGDITKLA----VDVIVNVTNPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPT 62
Query 1078 GGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPLLS 1128
G + + +L AK +H VGP GE + QLL+ AY N NS + P +S
Sbjct 63 GHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAIS 122
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVE 1177
G++G + ++ V+TV + AL EQV D +
Sbjct 123 TGVYGYPRAAAAEIAVKTVSE----FITRHALPEQVYFVCYDEENAHLY 167
>sp|E1SDF1|YMDB1_PANVC O-acetyl-ADP-ribose deacetylase 1 OS=Pantoea
vagans (strain C9-1) OX=712898 GN=ymdB1 PE=3 SV=1
Length=171
Score = 140 bits (352), Expect = 6e-36, Method: Composition-based stats.
Identities = 42/165 (25%), Positives = 70/165 (42%), Gaps = 22/165 (13%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPL 1075
+ + DI K + IVNAAN L GGGV GA+++A + E G
Sbjct 4 ITVIQGDITKVS----AEAIVNAANSSLLGGGGVDGAIHRAGGPVILAECQLIRNRQGGC 59
Query 1076 TVGGSCLLSGHNL-AKKCLHVVGPNLNAG--EDIQLLKAAYEN------FNSQDILLAPL 1126
VG + + NL A +H VGP + G ++ LLK AY++ ++ + P
Sbjct 60 KVGDAVITGAGNLPADYVIHTVGPRWSDGRHDEDALLKRAYQSCFKLVDYHGIKTVSFPN 119
Query 1127 LSAGIFGAKPLQSLQVCVQTVR---------TQVYIAVNDKALYE 1162
+S GI+G ++ + + ++ V + D Y+
Sbjct 120 ISTGIYGFPKERAATIALDVIKHCIAENRTLENVNLVCFDAENYD 164
>sp|Q8EYT0|Y4133_LEPIN Macro domain-containing protein LA_4133
OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar
Lai (strain 56601) OX=189518 GN=LA_4133 PE=4 SV=1
Length=175
Score = 139 bits (350), Expect = 1e-35, Method: Composition-based stats.
Identities = 43/167 (26%), Positives = 74/167 (44%), Gaps = 21/167 (13%)
Query 1023 IVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL 1082
I ++ IVNAAN L GGGV GA+++A + +E + G VG + +
Sbjct 8 IKEDITQLEVDAIVNAANSSLLGGGGVDGAIHRAGGPEILEECYKIREKQGECKVGEAVI 67
Query 1083 LSGHNL-AKKCLHVVGPNLNAG--EDIQLLKAAYENF------NSQDILLAPLLSAGIFG 1133
+ L AK +H VGP + G + +LL AY+N +S + P +S GI+
Sbjct 68 TTAGRLNAKFIIHTVGPIWSGGNKNEDELLSNAYKNSLLLAKNHSLKTIAFPNISTGIYH 127
Query 1134 AKPLQSLQVCVQTVRT---------QVYIAVND---KALYEQVVMDY 1168
++ ++ +Q+V V+ D +Y +++ Y
Sbjct 128 FPKERAAKIAIQSVTEFLKQDNQIQTVFFVCFDFENLEIYNKLLQTY 174
>sp|Q72M93|Y3295_LEPIC Macro domain-containing protein LIC_13295
OS=Leptospira interrogans serogroup Icterohaemorrhagiae serovar
copenhageni (strain Fiocruz L1-130) OX=267671 GN=LIC_13295
PE=4 SV=1
Length=175
Score = 139 bits (350), Expect = 1e-35, Method: Composition-based stats.
Identities = 43/167 (26%), Positives = 74/167 (44%), Gaps = 21/167 (13%)
Query 1023 IVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL 1082
I ++ IVNAAN L GGGV GA+++A + +E + G VG + +
Sbjct 8 IKEDITQLEVDAIVNAANSSLLGGGGVDGAIHRAGGPEILEECYKIREKQGECKVGEAVI 67
Query 1083 LSGHNL-AKKCLHVVGPNLNAG--EDIQLLKAAYENF------NSQDILLAPLLSAGIFG 1133
+ L AK +H VGP + G + +LL AY+N +S + P +S GI+
Sbjct 68 TTAGRLNAKFIIHTVGPIWSGGNKNEDELLSNAYKNSLLLAKNHSLKTIAFPNISTGIYH 127
Query 1134 AKPLQSLQVCVQTVRT---------QVYIAVND---KALYEQVVMDY 1168
++ ++ +Q+V V+ D +Y +++ Y
Sbjct 128 FPKERAAKIAIQSVTKFLKQDNQIQTVFFVCFDFENLEIYNKLLQTY 174
>sp|P0C6F3|R1A_BEV Replicase polyprotein 1a OS=Berne virus OX=11156
GN=1a PE=1 SV=1
Length=4569
Score = 153 bits (386), Expect = 8e-35, Method: Composition-based stats.
Identities = 69/303 (23%), Positives = 113/303 (37%), Gaps = 24/303 (8%)
Query 881 VKTLQPVSDLLTNMGIDLDEWSVATFYLFDDAGEENFSSR--MYCSFYPPDEEEEDDAEC 938
K+ + M ++ + FD+A S + S PD A
Sbjct 1564 EKSKDDIFKAFNTMSLEQKKVLSHFCGEFDEAYTLQTMSDEISFESSAYPDVVACSLAYI 1623
Query 939 EEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPT 998
E+ T + E L+ G+ E V V+ + +++ + E+ E +
Sbjct 1624 LGYEMCLTVKVNAKNEK------LDIGSQCERVFVDYDVKKNEWTLSPEEGEDSDDNLDL 1677
Query 999 PEEPVNQF---TGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNK 1055
P E +F + L + + +K Q +VN AN LKHGGG+A ++
Sbjct 1678 PFEQYYEFKIGQTNVVLVQDDFKSVFEFLKSEQGV--DYVVNPANSQLKHGGGIAKVISC 1735
Query 1056 ATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKC--LHVVGPNLNAGEDIQLLKAAY 1113
+Q S++YI N + V + G L KK +H VGP ++ G+ Q L A+
Sbjct 1736 MCGPKLQAWSNNYITKNKTVPVTKAIKSPGFQLGKKVNIIHAVGPRVSDGDVFQKLDQAW 1795
Query 1114 ENF----NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT-----QVYIAVNDKALYEQV 1164
+ Q +L +LS GIFG S + V V++ N Y Q
Sbjct 1796 RSVFDLCEDQHTILTSMLSTGIFGCTVNDSFNTFLSNVARLDKSLVVFVVTNMVEQYNQA 1855
Query 1165 VMD 1167
Sbjct 1856 FAV 1858
Score = 52.0 bits (123), Expect = 3e-04, Method: Composition-based stats.
Identities = 56/246 (23%), Positives = 94/246 (38%), Gaps = 41/246 (17%)
Query 3005 ANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLM 3064
I +P V + V +V+ +I + + +Y F + +VV LLF+
Sbjct 3055 FEIISPYV--FVFIVVIFTVIFLILIRLYIVMYSY--------FKVFTYVVFK--LLFVN 3102
Query 3065 SFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFC 3124
+L +V +PGV L + + V FL +L + ++F I+P++ ++F
Sbjct 3103 IIMVLFVVCLPPLVPGVV----FVLALWLCDSVMFLLYLAFLSLF--ILPWFYVLFFLFM 3156
Query 3125 ISLKHCHWFFNNYLRKRVMFNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNR 3183
+ W + + +G+TF TFE+ + C F LN + + LL +
Sbjct 3157 VGGFVFWWMMRSADVVHLTTDGLTFNGTFEQISKCVFPLNP----LIVNRMLLDCQMSHS 3212
Query 3184 YLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGF 3243
L +K K G LA + +G YQP S QS F
Sbjct 3213 DLVEKSKLKTTEGK-------------LANEMMKVFMTGETSYYQPSNFSF-----QSVF 3254
Query 3244 RKMAFP 3249
K P
Sbjct 3255 SKATSP 3260
>sp|Q4J9D2|Y1252_SULAC Uncharacterized protein Saci_1252 OS=Sulfolobus
acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929
/ NBRC 15157 / NCIMB 11770) OX=330779 GN=Saci_1252 PE=4
SV=1
Length=181
Score = 136 bits (343), Expect = 1e-34, Method: Composition-based stats.
Identities = 48/179 (27%), Positives = 77/179 (43%), Gaps = 15/179 (8%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
V ++ DI K IVNAAN +L HGGGVA A+ ++ +Q+ESD+Y++ NGP
Sbjct 12 EVILENGDITKVE----ADAIVNAANSYLSHGGGVALAIVRSGGYIIQEESDEYVRRNGP 67
Query 1075 LTVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQLLKAAYENFNSQD-----ILLAPLLS 1128
+ VG + + L A+ +H VGP D +L A + D + P +S
Sbjct 68 VPVGEVAVTTAGKLKARYVIHAVGPRYGIEGDDKLESAIRRSLEKADELKLSSIALPAIS 127
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNT 1187
GI+G ++ + ++ K L +V+ Y D +
Sbjct 128 TGIYGYPYEICARIMSKVMKE-----YKPKFLKRILVVVYGDQAYSVFKKVFDNSLYMN 181
Score = 39.7 bits (91), Expect = 0.38, Method: Composition-based stats.
Identities = 17/114 (15%), Positives = 38/114 (33%), Gaps = 13/114 (11%)
Query 1229 LLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGD-------ITCVVIPSKK 1281
L + + +++ E ++ ++ P VG+V + + V P
Sbjct 36 LSHGGGVALAIVRSGGYIIQEESDEYVRRNGPVPVGEVAVTTAGKLKARYVIHAVGPRYG 95
Query 1282 AGGTTEM---LSRALKK---VPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAF 1329
G ++ + R+L+K + + G GY E + K +
Sbjct 96 IEGDDKLESAIRRSLEKADELKLSSIALPAISTGIYGYPYEICARIMSKVMKEY 149
>sp|Q8KAE4|Y2219_CHLTE Macro domain-containing protein CT2219
OS=Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC
103806 / TLS) OX=194439 GN=CT2219 PE=4 SV=1
Length=172
Score = 135 bits (341), Expect = 2e-34, Method: Composition-based stats.
Identities = 46/176 (26%), Positives = 75/176 (43%), Gaps = 19/176 (11%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ DNV I + + S IVNAAN L GGGV GA+++A + + +
Sbjct 1 MPDNVLIHAIKA--DITSLTVDAIVNAANTSLLGGGGVDGAIHRAAGPKLLEACREL--- 55
Query 1072 NGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENF------NSQDIL 1122
G G + + G+ L A +H VGP + G + +LL + Y N + +
Sbjct 56 -GGCLTGEAKITKGYRLPATFVIHTVGPVWHGGNHGEAELLASCYRNSLKLAIEHHCRTI 114
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
P +S GI+G Q+ + + TVR + D+ E+V+ + V
Sbjct 115 AFPSISTGIYGYPVEQAAAIAITTVRE----MLADERGIEKVIFCCFSDRDLDVYQ 166
>sp|Q96XY5|Y2383_SULTO Uncharacterized protein STK_23830 OS=Sulfurisphaera
tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140
/ 7) OX=273063 GN=STK_23830 PE=4 SV=1
Length=182
Score = 135 bits (341), Expect = 2e-34, Method: Composition-based stats.
Identities = 50/164 (30%), Positives = 75/164 (46%), Gaps = 15/164 (9%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPL 1075
V I DI + IVNAAN +L+HGGGVA A+ + +QKES +Y++ GP+
Sbjct 3 VKIIKGDITEIE----AEAIVNAANSYLEHGGGVARAIVEKGGYIIQKESREYVRKYGPV 58
Query 1076 TVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQLLKAAYENFNSQ------DILLAPLLS 1128
GG + S L AK +H VGP E + L+ A N + + P +S
Sbjct 59 PTGGVAVTSAGKLKAKYVIHAVGPRYGI-EGEEKLEEAIRNALRKAEELKLSSIALPAIS 117
Query 1129 AGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNL 1172
GI+G + V+ ++ + N K L +V Y +
Sbjct 118 TGIYGYPYEICAEKMVKVIKEE---YTNFKHLNTIIVSLYSEEA 158
>sp|Q8ZXT3|Y1111_PYRAE Uncharacterized protein PAE1111 OS=Pyrobaculum
aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630
/ CIP 104966 / NBRC 100827 / IM2) OX=178306 GN=PAE1111 PE=4
SV=1
Length=182
Score = 134 bits (336), Expect = 1e-33, Method: Composition-based stats.
Identities = 46/170 (27%), Positives = 79/170 (46%), Gaps = 21/170 (12%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
V + DI + IVNAAN +L+HGGGVAGA+ + +Q+ES ++++ +GP
Sbjct 9 EVVLMRGDITEVE----ADAIVNAANSYLEHGGGVAGAIVRKGGQVIQEESREWVRKHGP 64
Query 1075 LTVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQLLKAAYENFNSQD------ILLAPLL 1127
+ VG + S L AK +H VGP E I+ L A +N + + P +
Sbjct 65 VPVGDVAVTSAGRLKAKYVIHAVGPRC-GVEPIEKLAEAVKNALLKAEELGLVSIALPAI 123
Query 1128 SAGIFGAKPLQSLQVCVQTVRT---------QVYIAVNDKALYEQVVMDY 1168
S GIFG + + +R ++ + + + Y++ + +
Sbjct 124 STGIFGCPYDAAAEQMATAIREVAPALRSIRRILVVLYGEEAYQKFLEVF 173
Score = 35.4 bits (80), Expect = 10.0, Method: Composition-based stats.
Identities = 15/73 (21%), Positives = 26/73 (36%), Gaps = 8/73 (11%)
Query 1229 LLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVITSGD-------ITCVVIPSKK 1281
L + G + +++ E ++ K P VGDV + + V P
Sbjct 33 LEHGGGVAGAIVRKGGQVIQEESREWVRKHGPVPVGDVAVTSAGRLKAKYVIHAVGPRCG 92
Query 1282 AGGTTEMLSRALK 1294
E L+ A+K
Sbjct 93 V-EPIEKLAEAVK 104
>sp|Q97UU4|Y2899_SACS2 Uncharacterized protein SSO2899 OS=Saccharolobus
solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322
/ P2) OX=273057 GN=SSO2899 PE=4 SV=1
Length=177
Score = 133 bits (335), Expect = 1e-33, Method: Composition-based stats.
Identities = 49/172 (28%), Positives = 78/172 (45%), Gaps = 17/172 (10%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
+ + DI + IVNAAN +L+HGGGVA A+ + +QKESD+Y+K GP
Sbjct 9 EIYLIKGDITEIE----ADAIVNAANSYLQHGGGVAYAIVRKGGYIIQKESDEYVKKFGP 64
Query 1075 LTVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQLLKAAYENFNSQD-----ILLAPLLS 1128
+ VG + S L AK +H VGP + +L A +++ D + P +S
Sbjct 65 VPVGEVAVTSAGKLKAKYVIHAVGPRYGIEGEDKLESAIFKSLLKADELSLSSIAMPAIS 124
Query 1129 AGIFGAKPLQSLQVCVQTVR-------TQVYIAVNDKALYEQVVMDYLDNLK 1173
GI+G ++ ++ +V I + K Y+ + LK
Sbjct 125 TGIYGYPFEICARIMANVLKGYKPKTLRKVMICLYTKDAYDVFKSIFNSILK 176
Score = 39.7 bits (91), Expect = 0.34, Method: Composition-based stats.
Identities = 27/159 (17%), Positives = 47/159 (30%), Gaps = 32/159 (20%)
Query 1208 IKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMSFLEKDAPYMVGDVI 1267
IK I E+ + L + + +++ E +++K P VG+V
Sbjct 13 IKGDITEIEADAIVNA-ANSYLQHGGGVAYAIVRKGGYIIQKESDEYVKKFGPVPVGEVA 71
Query 1268 TSGD-------ITCVVIPSKKAGGTTEMLSRALK------KVPVDEYITTYPGQGCAGYT 1314
+ + V P G ++ S K ++ + G GY
Sbjct 72 VTSAGKLKAKYVIHAVGPRYGIEGEDKLESAIFKSLLKADELSLSSIAMPAISTGIYGYP 131
Query 1315 LE-------------EAKTALK-----KCKSAFYVLPSE 1335
E + KT K K A+ V S
Sbjct 132 FEICARIMANVLKGYKPKTLRKVMICLYTKDAYDVFKSI 170
>sp|Q9WYX8|Y508_THEMA Uncharacterized protein TM_0508 OS=Thermotoga
maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC
100826 / MSB8) OX=243274 GN=TM_0508 PE=3 SV=1
Length=599
Score = 143 bits (361), Expect = 3e-33, Method: Composition-based stats.
Identities = 53/174 (30%), Positives = 82/174 (47%), Gaps = 15/174 (9%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPL 1075
+ I DI +E IVNAAN +LKHGGGVAGA+ +A +Q+ESD ++ G +
Sbjct 429 IRIVKGDITREE----VDAIVNAANEYLKHGGGVAGAIVRAGGSVIQEESDRIVQERGRV 484
Query 1076 TVGGSCLLSGHNL-AKKCLHVVGPNLNA---GEDIQLLKAAYENF-----NSQDILLAPL 1126
G + + S L AK +H VGP GED L KA Y + P
Sbjct 485 PTGEAVVTSAGKLKAKYVIHTVGPVWRGGSHGEDELLYKAVYNALLRAHELKLKSISMPA 544
Query 1127 LSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPK 1180
+S GIFG +++ + + +R +I + E++ + +D ++ K
Sbjct 545 ISTGIFGFPKERAVGIFSKAIRD--FIDQHPDTTLEEIRICNIDEETTKIFEEK 596
>sp|P0C6F4|R1A_BRV1 Replicase polyprotein 1a OS=Breda virus 1
OX=360393 GN=1a PE=3 SV=1
Length=4445
Score = 144 bits (363), Expect = 4e-32, Method: Composition-based stats.
Identities = 53/203 (26%), Positives = 87/203 (43%), Gaps = 17/203 (8%)
Query 956 DYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGY------ 1009
D + L+ G+S E V V+ + ++ D +T ++ + E P NQ+ +
Sbjct 1589 DGECESLDVGSSLEQVYVDYDVSKNVWDLSTH---LQDDSSDDLELPFNQYYEFKVGRAS 1645
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
+ L + D +K Q +VN AN LKHGGG+A ++ + S++YI
Sbjct 1646 VVLVQDDFKSVYDFLKSEQGV--DYVVNPANNQLKHGGGIAKVISCMCGPKLTSWSNNYI 1703
Query 1070 KLNGPLTVGGSCLLSGHNLAK--KCLHVVGPNLNAGEDIQLLKA----AYENFNSQDILL 1123
K L V + G L K + +HVVGP + + L+A ++N +L
Sbjct 1704 KQYKKLGVTCAIRSPGFQLGKGVQIIHVVGPKSADSDVVNKLEASWRSVFQNVKPDTTVL 1763
Query 1124 APLLSAGIFGAKPLQSLQVCVQT 1146
+LS GIFG S +
Sbjct 1764 TSMLSTGIFGCSVTDSATTLLSN 1786
Score = 54.3 bits (129), Expect = 7e-05, Method: Composition-based stats.
Identities = 53/227 (23%), Positives = 87/227 (38%), Gaps = 31/227 (14%)
Query 3024 VVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYS 3083
VV I I+ ++ F + +VV LLF+ + +L +V +PGV
Sbjct 2944 VVLVAIFTIVFLFLLRMYIVMYSYFKVFTYVVFK--LLFVNTVMVLFVVCLPPLVPGVV- 3000
Query 3084 VFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVM 3143
L + + V FL +L ++F I+P++ ++V + W + +
Sbjct 3001 ---FVLALWLCDSVVFLLYLAVLSLF--ILPWFYVMLFVLIVGGFVFWWMMKSSDVVHLT 3055
Query 3144 FNGVTF-STFEEAALCTFLLNKEMYLKLRSETLLPLTQYNRYLALYNKYKYFSGALDTTS 3202
+G+TF TFE+ + C F LN + + LL + L +K K G
Sbjct 3056 PDGLTFNGTFEQVSKCVFPLNP----LIVNRLLLDCRMSHSDLVEKSKLKTTEGK----- 3106
Query 3203 YREAACCHLAKALNDFSNSGADVLYQPPQTSITSAVLQSGFRKMAFP 3249
LA + +G YQP S QS F K+ P
Sbjct 3107 --------LATEMMKVFMTGETAYYQPSNFSF-----QSVFSKVVSP 3140
>sp|Q8RB30|Y995_CALS4 Macro domain-containing protein TTE0995
OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain
DSM 15242 / JCM 11007 / NBRC 100824 / MB4) OX=273068 GN=TTE0995
PE=4 SV=1
Length=175
Score = 129 bits (323), Expect = 5e-32, Method: Composition-based stats.
Identities = 39/147 (27%), Positives = 64/147 (44%), Gaps = 13/147 (9%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ + + + +IV + IVNAAN L GGGV GA++KA A+ +E +
Sbjct 1 MKEKIKLIKGNIVDQE----VDAIVNAANSSLIGGGGVDGAIHKAGGPAIAEELKVIREK 56
Query 1072 NGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAG--EDIQLLKAAYENFNSQ------DIL 1122
G G + + NL AK +H VGP G + LL +AY +
Sbjct 57 QGGCPTGHAVITGAGNLKAKYVIHAVGPIWKGGNHNEDNLLASAYIESLKLADEYNVKTI 116
Query 1123 LAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
P +S G +G ++ ++ ++ V
Sbjct 117 AFPSISTGAYGFPVERAARIALRVVSD 143
>sp|Q5ZKG3|DNA2_CHICK DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Gallus gallus OX=9031 GN=DNA2 PE=2 SV=2
Length=992
Score = 141 bits (356), Expect = 1e-31, Method: Composition-based stats.
Identities = 72/375 (19%), Positives = 130/375 (35%), Gaps = 86/375 (23%)
Query 5571 QKVGMQKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKALKY--- 5625
Q + + Y+ + G PGTGK+ A+ L ++ T+ +H AVD + K K+
Sbjct 605 QVLLSRDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSFTHTAVDNILLKLAKFKVG 664
Query 5626 -LPIDKCSRIIPARARV------------------ECFDKFKVNSTLEQYVFCTVNALPE 5666
L + + ++ P + E ++ V +T + +
Sbjct 665 FLRLGRAQKVHPDIRKFTEEEICRSKSIKSVTDLEELYNSQPVVATACMGI--NHPIFVQ 722
Query 5667 TTADIVVFDEISMATNYDLSVVNARLRA-KHYVYIGDPAQLPA--PRTLLTKGTLEPEYF 5723
D + DE S + + L K +V +GD QLP + + F
Sbjct 723 KQFDFCIVDEASQISQ---PICLGPLFCSKRFVLVGDHQQLPPLVQNSEARDLGMSESLF 779
Query 5724 NSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITH 5783
RL + + L R ++I+ + LVY+ KL+ +K
Sbjct 780 K---RLEQNQNAVVQLTVQYRMNSKIMSLSNKLVYEGKLECGSEK--------------- 821
Query 5784 DVSSAINRPQIGVVR-EFLTRNPAW-----------------------RKAVFISPYNSQ 5819
++ N P + +++ EF + W ISPY Q
Sbjct 822 VSNATANLPNLKMLKLEFADASKTWLKEVLEPDKPVCFLNTEKAGCRPSDIGIISPYRHQ 881
Query 5820 NAVASKILG------LPTQTVDSSQGSEYDYVIFTQTTETAHSC------NVNRFNVAIT 5867
V + ++ + T+D QG + +I + + + R NVAIT
Sbjct 882 LKVITDLMARLKENRVEVNTIDKYQGRDKSIIIVSFVRNSNDENLGALLKDWRRLNVAIT 941
Query 5868 RAKIGILCIMSDRDL 5882
RAK ++ + L
Sbjct 942 RAKHKLIMVGCVPSL 956
>sp|Q8Q0F9|Y177_METMA Macro domain-containing protein MM_0177
OS=Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1
/ Go1 / JCM 11833 / OCM 88) OX=192952 GN=MM_0177 PE=4 SV=1
Length=187
Score = 128 bits (321), Expect = 1e-31, Method: Composition-based stats.
Identities = 49/164 (30%), Positives = 71/164 (43%), Gaps = 26/164 (16%)
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNG 1073
D + I DIVK IVNAAN L GGGV GA+++A A+ +E LNG
Sbjct 19 DRIRIFEGDIVK----MRVDAIVNAANNTLLGGGGVDGAIHRAAGPALLEECKT---LNG 71
Query 1074 PLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENFNSQ------DILLA 1124
G + + SG+ L AK +H VGP GE + +LL + Y +
Sbjct 72 -CPTGEAKITSGYLLPAKYIIHTVGPVWQGGEKGEDELLASCYRKSLELARDYKIKTIAF 130
Query 1125 PLLSAGIFGAKPLQSLQVCVQTVR---------TQVYIAVNDKA 1159
P +S G +G ++ + V V+ VY+ +K
Sbjct 131 PAISTGAYGFPSERAAGIAVSQVKEFLQKNEIPETVYLVCYNKD 174
>sp|O94387|YGSA_SCHPO Uncharacterized ATP-dependent helicase C29A10.10c
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
OX=284812 GN=SPBC29A10.10c PE=3 SV=1
Length=1944
Score = 142 bits (357), Expect = 1e-31, Method: Composition-based stats.
Identities = 68/305 (22%), Positives = 110/305 (36%), Gaps = 43/305 (14%)
Query 5668 TADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC 5727
T V+ DE + A S++ + + V +GDP QLP T+L+K + + Y S+
Sbjct 1509 TFRTVIIDEAAQAVELS-SIIPLKYGCESCVMVGDPNQLPP--TVLSKTSAKFGYSQSLY 1565
Query 5728 RLM--KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQC------------- 5772
M + L R EI S Y++KL + SA
Sbjct 1566 VRMFKQHNESACLLSIQYRMNPEISRFPSKFFYNSKLLDGPNMSAVTSRPWHEDPQLGIY 1625
Query 5773 -FKMFYKGVITHDVSSAINRPQIGVVREFLTRNPA-------WRKAVFISPYNSQNAVAS 5824
F + + S N + + R K ++PY SQ
Sbjct 1626 RFFNVHGTEAFSNSKSLYNVEEASFILLLYERLIQCYLNIDFEGKIGVVTPYRSQVQQLR 1685
Query 5825 KILG----------LPTQTVDSSQGSEYDYVIFTQTTET-----AHSCNVNRFNVAITRA 5869
L TVD QG E D +IF+ + ++ R NVA+TRA
Sbjct 1686 SQFQRKYGSIIFKHLDIHTVDGFQGQEKDIIIFSCVRSSMSGGIGFLQDLRRLNVALTRA 1745
Query 5870 KIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHL 5929
K + + + + L + F SL I + + FK+ SK I+ + A +L
Sbjct 1746 KSSLYIVGNSKPLMQEDIFYSL-IEDAKTRGVWRDLSANQFKN-SKSISNVSTHLASNNL 1803
Query 5930 SVDIK 5934
++ +
Sbjct 1804 NLASR 1808
Score = 44.3 bits (103), Expect = 0.065, Method: Composition-based stats.
Identities = 24/128 (19%), Positives = 45/128 (35%), Gaps = 24/128 (19%)
Query 5537 SAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGL 5596
P+ + +I Y +N ++ Y ++ +QGPPGTGK+ +G+
Sbjct 1252 RLPSNFTDDKKQKIMKSY-GVNEPQAYA----IYASSVNDGFTLIQGPPGTGKTKTILGM 1306
Query 5597 ALY-------------------YPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPA 5637
+I+ A S+AA+D + + + + + P
Sbjct 1307 IGAVLTSSSQGLQFNVPGQTRKTSKNKILICAPSNAAIDEILLRIKAGVYDHEGIKFFPK 1366
Query 5638 RARVECFD 5645
RV D
Sbjct 1367 VIRVGFGD 1374
>sp|E1PL40|YMDB2_PANVC O-acetyl-ADP-ribose deacetylase 2 OS=Pantoea
vagans (strain C9-1) OX=712898 GN=ymdB2 PE=3 SV=1
Length=171
Score = 126 bits (317), Expect = 2e-31, Method: Composition-based stats.
Identities = 38/165 (23%), Positives = 65/165 (39%), Gaps = 22/165 (13%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPL 1075
+ + DI A A I+N AN L GGGV GA+++A + E G
Sbjct 4 ITVIQGDITNIASEA----IINVANSSLLGGGGVDGAIHRAGGPVILAECQAIRSRQGGC 59
Query 1076 TVGGSCLLSGHNL-AKKCLHVVGPNLNAG--EDIQLLKAAYENF------NSQDILLAPL 1126
VG + + L A +H VGP + G + LK+ Y + + + P
Sbjct 60 KVGEAVITGAGTLPADYVIHTVGPRWSDGRHNEDTQLKSVYLSCFKLVGHHGIKTVSFPN 119
Query 1127 LSAGIFGAKPLQSLQVCVQTVR---------TQVYIAVNDKALYE 1162
+S GI+G ++ + + ++ +V + D Y+
Sbjct 120 ISTGIYGFPKKRAAAIALDVIKHCIAENRTIEKVNLVCFDAENYD 164
>sp|Q9HEH1|RENT1_NEUCR Regulator of nonsense transcripts 1 homolog
OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A /
CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=2E4.130 PE=3
SV=1
Length=1093
Score = 140 bits (353), Expect = 3e-31, Method: Composition-based stats.
Identities = 91/447 (20%), Positives = 164/447 (37%), Gaps = 104/447 (23%)
Query 5528 LTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGT 5587
L H V APT + + GL + +S +A ++V S +QGPPGT
Sbjct 430 LLGHEVQ--VAPTKITMPKKFHVPGL------PELNASQIAAIKQVLSNPLSLIQGPPGT 481
Query 5588 GKS----HFAIGLALYYPSARIVYTACSHAAVDALCEK----ALKYLPIDKCSR--IIPA 5637
GK+ LA +++++ A S+ AVD LCE+ LK + + SR + +
Sbjct 482 GKTVTSATIIYHLAKMS-NSQVLVCAPSNVAVDQLCERIHRTGLKVVRLTAKSREDVESS 540
Query 5638 RARVECFDKFKVNSTLEQ--------------------------------------YVFC 5659
+ + ++ ++N+T ++ V C
Sbjct 541 VSFLALHEQVRMNTTNKELDGLVKLKTETGELSSQDEKRFKQLTRQAEREILQNADVVCC 600
Query 5660 T-VNA----LPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLT 5714
T V A L + V+ DE + + + ++ L K V +GD QL ++
Sbjct 601 TCVGAGDPRLSKMKFRNVLIDESTQSAEPEC-MIPLVLGCKQVVLVGDHKQLGP--VIMN 657
Query 5715 KGTLEPEYFNSVC-RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQC- 5772
K + S+ RL+K + L R + + S + Y+ L+ + +
Sbjct 658 KKAAKAGLNQSLFERLVKLQFTPIRLKVQYRMHPCLSEFPSNMFYEGSLQNGVTAAERLR 717
Query 5773 -----------FKMFYKGVITHDVSSA-----INRPQIGVVREFLTRN----PAWRKAVF 5812
M + + ++ SA +NR + V + +TR
Sbjct 718 KDVDFPWPVPETPMMFWSNLGNEEISASGTSYLNRTEAANVEKIVTRFFKAGVKPADIGV 777
Query 5813 ISPYNSQN------------AVASKILGLPTQTVDSSQGSEYDYVIFT-----QTTETAH 5855
I+PY Q + +VD+ QG E D+++ + +
Sbjct 778 ITPYEGQRSYIVNTMQNTGTFKKESYREVEVASVDAFQGREKDFIVLSCVRSNENQGIGF 837
Query 5856 SCNVNRFNVAITRAKIGILCIMSDRDL 5882
+ R NVA+TRAK G++ I + + L
Sbjct 838 LSDPRRLNVALTRAKYGLVIIGNPKVL 864
>sp|Q09820|RENT1_SCHPO ATP-dependent helicase upf1 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=upf1
PE=3 SV=2
Length=925
Score = 139 bits (350), Expect = 4e-31, Method: Composition-based stats.
Identities = 83/404 (21%), Positives = 143/404 (35%), Gaps = 100/404 (25%)
Query 5576 QKYSTLQGPPGTGKS----HFAIGLALYYPSAR-----IVYTACSHAAVDALCEK----A 5622
+ S +QGPPGTGK+ LA R ++ A S+ AVD L EK
Sbjct 407 KPLSLIQGPPGTGKTVTSASVVYHLATMQSRKRKSHSPVLVCAPSNVAVDQLAEKIHRTG 466
Query 5623 LKYLPIDKCSR----------IIPARARVECFDK-----FKVNSTL-------------- 5653
L+ + + SR + + + F+ K+ S
Sbjct 467 LRVVRVAAKSREDIESSVSFLSLHEQIKNYKFNPELQRLLKLRSENNELSIQDEKKLRIL 526
Query 5654 -----------EQYVFCT-VNA----LPETTADIVVFDEISMATNYDLSVVNARLRAKHY 5697
+ CT V A + + V+ DE + A+ + ++ L AK
Sbjct 527 VAAAEKELLRAAHVICCTCVGAGDRRISKYKFRSVLIDEATQASEPEC-MIPLVLGAKQV 585
Query 5698 VYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMF-LGTCRRCPAEIVDTVSAL 5756
V +GD QL P + K L S+ + +G F L R + + S
Sbjct 586 VLVGDHQQL-GPVVMNKKVALA-SLSQSLFERLIILGNSPFRLVVQYRMHPCLSEFPSNT 643
Query 5757 VYDNKLKAHKDKSAQCFKMF------------YKGVITHDVSSA-----INRPQIG---- 5795
Y+ L+ S + + + + SA +NR +
Sbjct 644 FYEGTLQNGVTTSERIARHVDFPWIQPDSPLMFYANFGQEELSASGTSFLNRTEASTCEK 703
Query 5796 VVREFLTRNPAWRKAVFISPYNSQNAVASKIL------------GLPTQTVDSSQGSEYD 5843
+V FL N + ++PY+ Q + + + + +VD+ QG E D
Sbjct 704 IVTTFLRSNVLPEQIGIVTPYDGQRSYIVQYMQNNGSMQKDLYKAVEVASVDAFQGREKD 763
Query 5844 YVIFTQTTETAH-----SCNVNRFNVAITRAKIGILCIMSDRDL 5882
++I + + H + R NVA+TRAK G++ + + + L
Sbjct 764 FIILSCVRSSEHQGIGFVNDPRRLNVALTRAKYGVIVLGNPKVL 807
>sp|E1BMP7|DNA2_BOVIN DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Bos taurus OX=9913 GN=DNA2 PE=3 SV=3
Length=1061
Score = 139 bits (349), Expect = 7e-31, Method: Composition-based stats.
Identities = 75/386 (19%), Positives = 123/386 (32%), Gaps = 84/386 (22%)
Query 5576 QKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKALKYL------- 5626
+ Y+ + G PGTGK+ + LY ++ T+ +H+AVD + K K+
Sbjct 641 KDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLG 700
Query 5627 ----PIDKCSRIIPARA-RVECFDKFKV-----NSTLEQYVFC---TVNALPETTADIVV 5673
+ R + + NS L C T D +
Sbjct 701 QIQKVHPDIQKFTEEEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKTFDFCI 760
Query 5674 FDEISMATNYDLSVVNARLRA-KHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC-RLMK 5731
DE S + V L + +V +GD QLP +L + S+ RL +
Sbjct 761 VDEASQISQ---PVCLGPLFFSRRFVLVGDHQQLPP--LVLNREARALGMSESLFKRLEQ 815
Query 5732 TIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK---------------------------- 5763
+ L R ++I+ + L Y+ KL+
Sbjct 816 NKNAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLPNFKDVKLELEFYAD 875
Query 5764 ---------AHKDKSAQCFKMFYK--GVITHDVSSAINRPQIGVVR----EFLTRNPAWR 5808
A + + CF +K + N + +V F+
Sbjct 876 YSENPWLIAAFEPNNPVCFLNTHKVPAPEQVEKGGVSNIMEAKLVVFLTSVFIKAGCKPS 935
Query 5809 KAVFISPYNSQNAVASKILG------LPTQTVDSSQGSEYDYVIFTQTTETAHSC----- 5857
I+PY Q V S +L + TVD QG + V+ +
Sbjct 936 DIGIIAPYRQQLKVISDLLAQSSVGMVEVNTVDRYQGRDKSIVVVSFVRSNEDGTLGELL 995
Query 5858 -NVNRFNVAITRAKIGILCIMSDRDL 5882
+ R NVAITRAK ++ + L
Sbjct 996 KDWRRLNVAITRAKHKLILLGCVPSL 1021
>sp|Q9VYS3|RENT1_DROME Regulator of nonsense transcripts 1 homolog
OS=Drosophila melanogaster OX=7227 GN=Upf1 PE=1 SV=2
Length=1180
Score = 139 bits (349), Expect = 8e-31, Method: Composition-based stats.
Identities = 83/422 (20%), Positives = 136/422 (32%), Gaps = 95/422 (23%)
Query 5552 GLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS----HFAIGLALYYPSARIVY 5607
L+ ++ D S V + + S +QGPPGTGK+ L + ++
Sbjct 442 KLFSAPHLPDLNRSQVYAVKHALQRPLSLIQGPPGTGKTVTSATIVYQLVKLH-GGTVLV 500
Query 5608 TACSHAAVDALCEKALK--YLPIDKCSRIIPARA-------------RVECFDKFKV--- 5649
A S+ AVD L EK + + C++ A +E + K
Sbjct 501 CAPSNTAVDQLTEKIHRTNLKVVRVCAKSREAIDSPVSFLALHNQIRNMETNSELKKLQQ 560
Query 5650 --NSTL------------------------EQYVFCTV-----NALPETTADIVVFDEIS 5678
+ T + CT L ++ DE
Sbjct 561 LKDETGELSSADEKRYRNLKRAAENQLLEAADVICCTCVGAGDGRLSRVKFTSILIDESM 620
Query 5679 MATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMF 5738
+T + +V L AK + +GD QL ++ K S+ + +G F
Sbjct 621 QSTEPEC-MVPVVLGAKQLILVGDHCQLGP--VVMCKKAARAGLSQSLFERLVVLGIRPF 677
Query 5739 -LGTCRRCPAEIVDTVSALVYDNKLK--------------AHKDKSAQCFKMFYKGVITH 5783
L R E+ S Y+ L+ F + +G
Sbjct 678 RLEVQYRMHPELSQFPSNFFYEGSLQNGVCAEDRRLKLDFPWPQPERPMFFLVTQGQEEI 737
Query 5784 DVS--SAINRPQIGVVR----EFLTRNPAWRKAVFISPYNSQNAVASKIL---------- 5827
S S +NR + V FL + I+PY Q A + +
Sbjct 738 AGSGTSFLNRTEAANVEKITTRFLKAGIKPEQIGIITPYEGQRAYLVQYMQYQGSLHSRL 797
Query 5828 --GLPTQTVDSSQGSEYDYVIFTQTTE-----TAHSCNVNRFNVAITRAKIGILCIMSDR 5880
+ +VD+ QG E D +I + + R NVA+TRAK GI+ + + +
Sbjct 798 YQEIEIASVDAFQGREKDIIIMSCVRSNERQGIGFLNDPRRLNVALTRAKFGIIIVGNPK 857
Query 5881 DL 5882
L
Sbjct 858 VL 859
>sp|Q86AS0|Y4399_DICDI Probable helicase DDB_G0274399 OS=Dictyostelium
discoideum OX=44689 GN=DDB_G0274399 PE=3 SV=1
Length=967
Score = 137 bits (345), Expect = 2e-30, Method: Composition-based stats.
Identities = 59/297 (20%), Positives = 111/297 (37%), Gaps = 35/297 (12%)
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
+ R D+ + +T + ++ DIV+ DE + A +++ + K
Sbjct 553 SSIRTLVLDEADIVATTLSFSGASLLTKMAGGFDIVIIDEAAQAVETS-TLIPIQHGCKK 611
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5756
V +GDP QLPA T+++ ++ +Y S+ + ++ L T R + I S
Sbjct 612 VVLVGDPKQLPA--TIISPLAIKYKYDQSLFQRLQEKNSPHMLTTQYRMHSLIRAFPSRH 669
Query 5757 VYDNKLKAHKDKSAQC--------------FKMFYKGVITHDVSSAINRPQ----IGVVR 5798
Y + L + ++ + + + S N + + + +
Sbjct 670 FYQDLLLDGPNIPSRATHYHSNPFFGPLVFYDLSWSTETKPGGGSVFNEHECKMAMYLFQ 729
Query 5799 EFLTRNPAW---RKAVFISPYNSQNAVASKIL----GLPTQTVDSSQGSEYDYVIFT--- 5848
F P + ISPY Q +I G+ TVD QG E + +IF+
Sbjct 730 LFTKVYPDEDFASRIGIISPYRQQVLALREIFKNYPGISIDTVDGFQGREREIIIFSCVR 789
Query 5849 ----QTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATL 5901
+ +V R NVA+TR + +L + + + L + L +N L
Sbjct 790 APVEEGAGIGFLSDVRRMNVALTRPRSSLLILGNTKALSINKDWNELIQHTQNNQQL 846
>sp|Q00416|SEN1_YEAST Helicase SEN1 OS=Saccharomyces cerevisiae
(strain ATCC 204508 / S288c) OX=559292 GN=SEN1 PE=1 SV=2
Length=2231
Score = 138 bits (347), Expect = 3e-30, Method: Composition-based stats.
Identities = 56/256 (22%), Positives = 85/256 (33%), Gaps = 43/256 (17%)
Query 5667 TTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSV 5726
D V+ DE T S++ R K + +GDP QLP T+L+ +Y S+
Sbjct 1582 IKFDTVIIDEACQCTELS-SIIPLRYGGKRCIMVGDPNQLPP--TVLSGAASNFKYNQSL 1638
Query 5727 CRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAH--------------KDKSAQC 5772
M+ L R I S+ Y +LK + +
Sbjct 1639 FVRMEKNSSPYLLDVQYRMHPSISKFPSSEFYQGRLKDGPGMDILNKRPWHQLEPLAPYK 1698
Query 5773 FKMFYKGVITHD--VSSAINRPQI--------GVVREFLTRNPAWRKAVFISPYNSQNAV 5822
F G + S N +I + R+F + K ISPY Q
Sbjct 1699 FFDIISGRQEQNAKTMSYTNMEEIRVAIELVDYLFRKFDNKIDFTGKIGIISPYREQMQK 1758
Query 5823 ASKIL----------GLPTQTVDSSQGSEYDYVIFT------QTTETAHSCNVNRFNVAI 5866
K + T+D QG E + ++ + + + R NVA+
Sbjct 1759 MRKEFARYFGGMINKSIDFNTIDGFQGQEKEIILISCVRADDTKSSVGFLKDFRRMNVAL 1818
Query 5867 TRAKIGILCIMSDRDL 5882
TRAK I + R L
Sbjct 1819 TRAKTSIWVLGHQRSL 1834
Score = 47.0 bits (110), Expect = 0.009, Method: Composition-based stats.
Identities = 25/100 (25%), Positives = 40/100 (40%), Gaps = 27/100 (27%)
Query 5573 VGMQKYSTLQGPPGTGKSHFAIGLALYYPSA---------------------------RI 5605
V + +S +QGPPGTGK+ +G+ Y+ S +I
Sbjct 1347 VSKEGFSLIQGPPGTGKTKTILGIIGYFLSTKNASSSNVIKVPLEKNSSNTEQLLKKQKI 1406
Query 5606 VYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFD 5645
+ A S+AAVD +C + + + + P RV D
Sbjct 1407 LICAPSNAAVDEICLRLKSGVYDKQGHQFKPQLVRVGRSD 1446
>sp|P23249|MOV10_MOUSE Putative helicase MOV-10 OS=Mus musculus
OX=10090 GN=Mov10 PE=1 SV=2
Length=1004
Score = 136 bits (342), Expect = 5e-30, Method: Composition-based stats.
Identities = 84/401 (21%), Positives = 131/401 (33%), Gaps = 103/401 (26%)
Query 5581 LQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID------- 5629
+ GPPGTGK+ + + P A I+ A S++ D LC++ +LP
Sbjct 523 IFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAP 582
Query 5630 -KCSRIIPARARVEC----------FDKFKVNSTLEQYVFCTVNA-------LPETTADI 5671
+ R++P + C + K + + A P
Sbjct 583 SRDIRMVPEDIKTCCNWDAKKGEYVYPAKKHLQQYRVLITTLITASRLVSAQFPIDHFTH 642
Query 5672 VVFDEISMATNYDLSVVNARLR--------AKHYVYIGDPAQL-PAPRTLLT-KGTLEPE 5721
+ DE + V A L V GDP QL P R+ L K L
Sbjct 643 IFIDEAGHCMEPESLVAIAGLMDVKETGNPGGQLVLAGDPRQLGPVLRSPLALKHGLGYS 702
Query 5722 Y------FNSVCRLMKTIGPDMFLGTC---RRCPAEIVDTVSALVYDNKLKAHKDKSA-- 5770
+NS+ + F+ R I+D + L YD +L+A D
Sbjct 703 LLERLLAYNSLYKKGPNGYDPQFITKLLRNYRSHPTILDIPNQLYYDGELQACADVVDRE 762
Query 5771 ----------QCFKMFYKGVITHDVS-----SAINRPQIGVVREFLTRN--PAWRKA--- 5810
Q F + + GV+ D S N + V +L + P+ +K
Sbjct 763 RFCRWEGLPQQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTSYLKQLLAPSSKKGKAR 822
Query 5811 ------VFISPYNSQNAVAS--------------KILGLPTQTVDSSQGSEYDYVIFTQT 5850
ISPY Q I L +V+ QG E ++ +
Sbjct 823 LSPRNVGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTV 882
Query 5851 TETA------------HSCNVNRFNVAITRAKIGILCIMSD 5879
+ N RFNVA+TRAK +L ++ +
Sbjct 883 RSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAK-ALLIVVGN 922
>sp|Q87JZ5|Y4103_VIBPA Macro domain-containing protein VPA0103
OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
OX=223926 GN=VPA0103 PE=4 SV=1
Length=170
Score = 122 bits (306), Expect = 7e-30, Method: Composition-based stats.
Identities = 39/150 (26%), Positives = 72/150 (48%), Gaps = 13/150 (9%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNG-P 1074
+++ DI +A+ IVNAAN + GGGV GA+++A A+ ++G
Sbjct 4 ISLVQGDIT----TAHVDAIVNAANPRMLGGGGVDGAIHRAAGPALINACYAVDDVDGIR 59
Query 1075 LTVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQ-LLKAAYEN------FNSQDILLAPL 1126
G + + NL A+ +H VGP + D + +L++AY+ N + P
Sbjct 60 CPFGDARITEAGNLNARYVIHAVGPIYDKFADPKTVLESAYQRSLDLALANHCQSVALPA 119
Query 1127 LSAGIFGAKPLQSLQVCVQTVRTQVYIAVN 1156
+S G++G P ++ +V + + Y A++
Sbjct 120 ISCGVYGYPPQEAAEVAMAVCQRPEYAALD 149
>sp|P30771|RENT1_YEAST ATP-dependent helicase NAM7 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=NAM7
PE=1 SV=1
Length=971
Score = 134 bits (338), Expect = 1e-29, Method: Composition-based stats.
Identities = 94/512 (18%), Positives = 176/512 (34%), Gaps = 121/512 (24%)
Query 5466 LSWEVGKPRPPLNRNYVFTGYRVTKNSKVQ-----IGEYTFEKGDYGDAVVYRGTTTYKL 5520
L + K PP + FT + K + + ++ +K + Y+
Sbjct 330 LELKPSKTPPPTHLTTGFTAEFIWKGTSYDRMQDALKKFAIDKKSISGYLYYK------- 382
Query 5521 NVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYST 5580
+ H V+ +S +P+E + P + SN V + S
Sbjct 383 -------ILGHQVVDISFDVPLPKEFSI------PNFAQLNSSQSNAV--SHVLQRPLSL 427
Query 5581 LQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAAVDALCEK----ALKYLPIDKCS 5632
+QGPPGTGK+ L+ + RI+ A S+ AVD L K LK + + S
Sbjct 428 IQGPPGTGKTVTSATIVYHLSKIHKD-RILVCAPSNVAVDHLAAKLRDLGLKVVRLTAKS 486
Query 5633 R--------------IIPARARVECFDKFKVNS------------------TLEQYVFCT 5660
R ++ A+ E + K+ E +
Sbjct 487 REDVESSVSNLALHNLVGRGAKGELKNLLKLKDEVGELSASDTKRFVKLVRKTEAEILNK 546
Query 5661 VNALP-----------ETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAP 5709
+ + +T V+ DE + A+ + ++ AK + +GD QL
Sbjct 547 ADVVCCTCVGAGDKRLDTKFRTVLIDESTQASEPEC-LIPIVKGAKQVILVGDHQQLGP- 604
Query 5710 RTLLTKGTLEPEYFNSVCRLMKTIGPD-MFLGTCRRCPAEIVDTVSALVYDNKLKAHKDK 5768
+L + + S+ + ++G + L R + + S + Y+ L+
Sbjct 605 -VILERKAADAGLKQSLFERLISLGHVPIRLEVQYRMNPYLSEFPSNMFYEGSLQNGVTI 663
Query 5769 SAQC-----FKMFYKGV------------ITHDVSSAINRPQIGVVREFLTRNPAW---- 5807
+ F +G+ I+ + +S +NR + +T+
Sbjct 664 EQRTVPNSKFPWPIRGIPMMFWANYGREEISANGTSFLNRIEAMNCERIITKLFRDGVKP 723
Query 5808 RKAVFISPYNSQNAVASKI------------LGLPTQTVDSSQGSEYDYVIFT-----QT 5850
+ I+PY Q A + + + +VD+ QG E DY+I + +
Sbjct 724 EQIGVITPYEGQRAYILQYMQMNGSLDKDLYIKVEVASVDAFQGREKDYIILSCVRANEQ 783
Query 5851 TETAHSCNVNRFNVAITRAKIGILCIMSDRDL 5882
+ R NV +TRAK G++ + + R L
Sbjct 784 QAIGFLRDPRRLNVGLTRAKYGLVILGNPRSL 815
>sp|P51530|DNA2_HUMAN DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Homo sapiens OX=9606 GN=DNA2 PE=1 SV=3
Length=1060
Score = 135 bits (339), Expect = 1e-29, Method: Composition-based stats.
Identities = 73/385 (19%), Positives = 127/385 (33%), Gaps = 83/385 (22%)
Query 5576 QKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKALKY----LPID 5629
+ Y+ + G PGTGK+ + LY ++ T+ +H+AVD + K K+ L +
Sbjct 641 KDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLG 700
Query 5630 KCSRIIPA-----RARVECFDKFKV--------NSTLEQYVFC---TVNALPETTADIVV 5673
+ ++ PA + K NS L C D +
Sbjct 701 QIQKVHPAIQQFTEQEICRSKSIKSLALLEELYNSQLIVATTCMGINHPIFSRKIFDFCI 760
Query 5674 FDEISMATNYDLSVVNARLRA-KHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC-RLMK 5731
DE S + + L + +V +GD QLP +L + S+ RL +
Sbjct 761 VDEASQISQ---PICLGPLFFSRRFVLVGDHQQLPP--LVLNREARALGMSESLFKRLEQ 815
Query 5732 TIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDK------SAQCFKMF--------- 5776
+ L R ++I+ + L Y+ KL+ DK + + FK
Sbjct 816 NKSAVVQLTVQYRMNSKIMSLSNKLTYEGKLECGSDKVANAVINLRHFKDVKLELEFYAD 875
Query 5777 ------------------------YKGVITHDVSSAINRPQIGVVR----EFLTRNPAWR 5808
+ N + ++ F+ +
Sbjct 876 YSDNPWLMGVFEPNNPVCFLNTDKVPAPEQVEKGGVSNVTEAKLIVFLTSIFVKAGCSPS 935
Query 5809 KAVFISPYNSQNAVASKILG-----LPTQTVDSSQGSEYDYVIFTQTTETAHSC------ 5857
I+PY Q + + +L + TVD QG + V+ +
Sbjct 936 DIGIIAPYRQQLKIINDLLARSIGMVEVNTVDKYQGRDKSIVLVSFVRSNKDGTVGELLK 995
Query 5858 NVNRFNVAITRAKIGILCIMSDRDL 5882
+ R NVAITRAK ++ + L
Sbjct 996 DWRRLNVAITRAKHKLILLGCVPSL 1020
>sp|Q1LXK4|M10B1_DANRE Putative helicase mov-10-B.1 OS=Danio rerio
OX=7955 GN=mov10b.1 PE=2 SV=2
Length=1013
Score = 133 bits (335), Expect = 3e-29, Method: Composition-based stats.
Identities = 83/397 (21%), Positives = 136/397 (34%), Gaps = 98/397 (25%)
Query 5580 TLQGPPGTGKSHFAI----GLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS--R 5633
+ GPPGTGK+ + + ARI+ A S++A D L EK + +D + R
Sbjct 547 LVFGPPGTGKTVTIVEAIKQVEKNTGGARILACAPSNSAADQLGEKLITSQHVDARNIYR 606
Query 5634 IIPARARVECFDKFKVNSTLE----------------QYVFCTV--------NALPETTA 5669
I + + K N++ + V CT+ P
Sbjct 607 IYASSRNPKEIPKVLENNSNVEGENIIFPCKEDLMPYKIVVCTLVTAGRLVSGGFPVGHF 666
Query 5670 DIVVFDEISMATNYDLSVVNARL---RAKHYVYIGDPAQLP-------APRTLLTKGTLE 5719
+ DE A ++ + A L V GDP QL A + L LE
Sbjct 667 SHIFVDEAGHAVEPEIVISVAGLLNAETGQLVLAGDPKQLGPILRSPFAIKYGLGLSLLE 726
Query 5720 PEYF-NSVCRLMKTIGPDMF---LGTCRRCPAEIVDTVSALVYDNKLKAHKDK------- 5768
N + + T + + L R I+ + L YDN+LKA D+
Sbjct 727 RLMTQNELYQKGDTGFDNRYVTKLLQNYRSHPSILKVPNELFYDNELKACADEISSRQYC 786
Query 5769 -----SAQCFKMFYKGVITHDVS-----SAINRPQIGVVREFLTRN-----------PAW 5807
+ F + + GV+ D S N +I + ++L + +
Sbjct 787 TWEHLPKRGFPVIFHGVVGKDERESTSPSFFNTSEIDKIMDYLKKLLLTQAKKGIAKISP 846
Query 5808 RKAVFISPYNSQNAVASKIL-------------GLPTQTVDSSQGSEYDYVIFTQTTETA 5854
+ I+PY Q + + L +V+ QG E +I + +
Sbjct 847 KDIGIIAPYRKQVEKIRQAIKIHRELKSLSGIEELKVGSVEEFQGQERKVIIVSTVRSSK 906
Query 5855 ------------HSCNVNRFNVAITRAKIGILCIMSD 5879
N RFNVA+TRAK +L ++ +
Sbjct 907 EHIILDDKFNIGFLKNEKRFNVAVTRAK-ALLIMVGN 942
>sp|Q2EMV9|PAR14_MOUSE Protein mono-ADP-ribosyltransferase PARP14
OS=Mus musculus OX=10090 GN=Parp14 PE=1 SV=3
Length=1817
Score = 134 bits (337), Expect = 3e-29, Method: Composition-based stats.
Identities = 47/183 (26%), Positives = 72/183 (39%), Gaps = 14/183 (8%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+K + ++ V+VNAAN +LKH G+A AL+KA +Q E D +K G +
Sbjct 813 VKLFVLEEDLSRFPVDVVVNAANENLKHISGLAQALSKAAGPELQTECDQIVKEGGVVLP 872
Query 1078 GGSCLLSGHNL-AKKCLHVVGPNLNAG---EDIQLLKAAYENF------NSQDILLAPLL 1127
G + + L +H VGP E + LLK + + P +
Sbjct 873 GNAVISKAGKLPCHHVIHAVGPRWKGDKVLECVSLLKKVVRQSLSLAEEHRCRSIAMPAV 932
Query 1128 SAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNT 1187
SAGIF L++CV + + + K + YL L +V E T
Sbjct 933 SAGIFDFP----LELCVANIVSAIKEHFQHKRDTHTLKKIYLVGLPAKVARAFAEAVKTT 988
Query 1188 EDS 1190
Sbjct 989 YKD 991
Score = 60.8 bits (146), Expect = 6e-07, Method: Composition-based stats.
Identities = 58/374 (16%), Positives = 116/374 (31%), Gaps = 50/374 (13%)
Query 1023 IVKEAQSANPMVIVNAANIHLK-HGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSC 1081
+ + Q+A IVN+ + LK + G ++ A + +Q+E + VG
Sbjct 1030 VEEGVQNATTHAIVNSISPDLKLNKGPLSQAFLEKAGPKLQEELTR-SGQGVSVDVGTIL 1088
Query 1082 LLSGHNL-AKKCLHVVGPNLNAGEDIQLLKAAYENFNSQ---------DILLAPLLSAGI 1131
SG NL ++ HVV P + LK + P + G
Sbjct 1089 QTSGCNLNSRHVFHVVPPPWKSNNSAWSLKIMKNIIRDCLKTTENLSLQSIAFPAIGTGN 1148
Query 1132 FGAKPLQSLQVCVQTV---------RTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQE 1182
+ ++ + V +T + + + + D R +
Sbjct 1149 LRFPKPEFAKLIISEVLKFSSRNQLKTLQEVQFLLHPKDHENIQAFSDEFDKRNNGDPSD 1208
Query 1183 EPPNTEDSKTEEKSVVQK----------PVDVKPKIKACIDEVTTTLEETKFLTNKLLLF 1232
+ P ED++ S+ P+ + I EV + + LT L
Sbjct 1209 KNPKAEDTQGIYGSLSSPTLGMHEMNIGPILFQVATGNIIKEVADVIVNSTTLTFDLKS- 1267
Query 1233 ADINGKLYHDSQNMLRGEDMSFLEKDAP-YMV--GDVITSGDITCVVIPSKKAGGTTEML 1289
++ + + + E ++ Y+V G ++ +I VV + + +L
Sbjct 1268 -GVSKAILEGAGQNVEQECSLLAKQSNHGYIVTGGGLLQCKNIIHVVGGNDVKKSVSCVL 1326
Query 1290 SRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKC----------KSAFYVLPSEAPNA 1339
++ Y + G ++ K KS V +
Sbjct 1327 EECEQR----NYSSICLPAIGTGNAQQDPNVVAKAIIDAIEEFVQKKSVQAVKRVKVVIF 1382
Query 1340 KEEILGTVSWNLRE 1353
+ IL N++E
Sbjct 1383 QPHILQFFYDNMKE 1396
Score = 57.4 bits (137), Expect = 6e-06, Method: Composition-based stats.
Identities = 41/250 (16%), Positives = 86/250 (34%), Gaps = 23/250 (9%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ +I+KE VIVN+ + GV+ A+ + +++E K +
Sbjct 1242 VATGNIIKEV----ADVIVNSTTLTFDLKSGVSKAILEGAGQNVEQECSLLAKQS----- 1292
Query 1078 GGSCLLSGHNL--AKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAK 1135
+++G L K +HVVG N +L+ + + + P + G
Sbjct 1293 NHGYIVTGGGLLQCKNIIHVVGGNDVKKSVSCVLEECEQ--RNYSSICLPAIGTGNAQQD 1350
Query 1136 PLQSLQVCVQTV-----RTQVYIAVNDKALYEQ--VVMDYLDNLKPRVEAPKQEEPPNTE 1188
P + + + + V K + Q ++ + DN+K R +P PP
Sbjct 1351 PNVVAKAIIDAIEEFVQKKSVQAVKRVKVVIFQPHILQFFYDNMKEREGSP---APPKQS 1407
Query 1189 DSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLR 1248
+K S + + + + + + + D K + ++
Sbjct 1408 PAKQSVMSKIASFLGFPKQASPKKNTLVLEKKIEHTVFQVCGSGVDSVNKTISWLKELIT 1467
Query 1249 GEDMSFLEKD 1258
E +S+ D
Sbjct 1468 KEQLSYTNDD 1477
>sp|Q9HCE1|MOV10_HUMAN Helicase MOV-10 OS=Homo sapiens OX=9606
GN=MOV10 PE=1 SV=2
Length=1003
Score = 133 bits (334), Expect = 4e-29, Method: Composition-based stats.
Identities = 86/401 (21%), Positives = 131/401 (33%), Gaps = 103/401 (26%)
Query 5581 LQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID------- 5629
+ GPPGTGK+ + + P A I+ A S++ D LC++ +LP
Sbjct 522 IFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAP 581
Query 5630 -KCSRIIPARARVEC----------FDKFKVNSTLEQYVFCTVNA-------LPETTADI 5671
+ R++P + C F K + + A P
Sbjct 582 SRDIRMVPEDIKPCCNWDAKKGEYVFPAKKKLQEYRVLITTLITAGRLVSAQFPIDHFTH 641
Query 5672 VVFDEISMATNYDLSVVNARLR--------AKHYVYIGDPAQL-PAPRTLLT-KGTLEPE 5721
+ DE + V A L V GDP QL P R+ LT K L
Sbjct 642 IFIDEAGHCMEPESLVAIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGYS 701
Query 5722 ------YFNSVCRLMKTIGPDMFLGTC---RRCPAEIVDTVSALVYDNKLKAHKDKSA-- 5770
+NS+ + F+ R I+D + L Y+ +L+A D
Sbjct 702 LLERLLTYNSLYKKGPDGYDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRE 761
Query 5771 ----------QCFKMFYKGVITHDVS-----SAINRPQIGVVREFLTRN--PAWRKA--- 5810
Q F + + GV+ D S N + V +L P+ +K
Sbjct 762 RFCRWAGLPRQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKAR 821
Query 5811 ------VFISPYNSQNAVAS--------------KILGLPTQTVDSSQGSEYDYVIFTQT 5850
ISPY Q I L +V+ QG E ++ +
Sbjct 822 LSPRSVGVISPYRKQVEKIRYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTV 881
Query 5851 TETA------------HSCNVNRFNVAITRAKIGILCIMSD 5879
+ N RFNVA+TRAK +L I+ +
Sbjct 882 RSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAK-ALLIIVGN 921
>sp|D3ZG52|DNA2_RAT DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Rattus norvegicus OX=10116 GN=Dna2 PE=3 SV=1
Length=1059
Score = 133 bits (334), Expect = 4e-29, Method: Composition-based stats.
Identities = 77/428 (18%), Positives = 142/428 (33%), Gaps = 98/428 (23%)
Query 5576 QKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKALKY----LPID 5629
+ Y+ + G PGTGK+ A+ L ++ T+ +H+AVD + K K+ L +
Sbjct 641 KDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSYTHSAVDNILLKLAKFKIGFLRLG 700
Query 5630 KCSRIIPARARV------------------ECFDKFKVNSTLEQYVFCTVNALPETTADI 5671
+ ++ P + E ++ V +T + + T D
Sbjct 701 QSHKVHPDIQKFTEEEMCRLRSIASLAHLEELYNSHPVVATTCMGI--SHPMFSRKTFDF 758
Query 5672 VVFDEISMATNYDLSVVNARLRA-KHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVC-RL 5729
+ DE S + + L + +V +GD QLP +L + S+ RL
Sbjct 759 CIVDEASQISQ---PICLGPLFFSRRFVLVGDHKQLPP--LVLNREARALGMSESLFKRL 813
Query 5730 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD---------------------- 5767
+ + L R +I+ + L Y+ KL+ D
Sbjct 814 ERNESAVVQLTIQYRMNRKIMSLSNKLTYEGKLECGSDRVANAVITLPNLKDVRLEFYAD 873
Query 5768 -------------KSAQCF--KMFYKGVITHDVSSAINRPQIGVVR----EFLTRNPAWR 5808
+ CF + N + ++ F+ +
Sbjct 874 YSDNPWLAGVFEPDNPVCFLNTDKVPAPEQIENGGVSNVTEARLIVFLTSTFIKAGCSPS 933
Query 5809 KAVFISPYNSQNAVASKILG------LPTQTVDSSQGSEYDYVIFTQTTETAHSC----- 5857
I+PY Q + +L + TVD QG + ++ +
Sbjct 934 DIGIIAPYRQQLRTITDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVRSNEDGTLGELL 993
Query 5858 -NVNRFNVAITRAKIGILCIMSDRD---------LYDKLQFTSLEIPRRNVATLQAENVT 5907
+ R NVAITRAK ++ + S L+D L L N+ + + E++
Sbjct 994 KDWRRLNVAITRAKHKLILLGSVSSLKRFPPLEKLFDHLNAEQL---ISNLPSREHESLY 1050
Query 5908 GLFKDCSK 5915
+ DC +
Sbjct 1051 HILGDCQR 1058
>sp|Q6ZQJ5|DNA2_MOUSE DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Mus musculus OX=10090 GN=Dna2 PE=1 SV=2
Length=1062
Score = 133 bits (334), Expect = 4e-29, Method: Composition-based stats.
Identities = 76/431 (18%), Positives = 139/431 (32%), Gaps = 102/431 (24%)
Query 5576 QKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKALKY----LPID 5629
+ Y+ + G PGTGK+ A+ L ++ T+ +H+AVD + K K+ L +
Sbjct 642 KDYTLIVGMPGTGKTTTICALVRILSACGFSVLLTSYTHSAVDNILLKLAKFKVGFLRLG 701
Query 5630 KCSRIIPARARV------------------ECFDKFKVNSTLEQYVFCTVNALPETTADI 5671
+ ++ P + E ++ + +T + T D
Sbjct 702 QSHKVHPDIQKFTEEEICRSRSIASLAHLEELYNSHPIVATTCMGI--NHPIFSRKTFDF 759
Query 5672 VVFDEISMATNYDLSVVNARLRA-KHYVYIGDPAQLPAPRTLLTKGTL--EPEYFNSVCR 5728
+ DE S + V L + +V +GD QLP L F R
Sbjct 760 CIVDEASQISQ---PVCLGPLFFSRRFVLVGDHQQLPPLVVNREARALGMSESLFK---R 813
Query 5729 LMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD--------------------- 5767
L + + L R +I+ + L Y KL+ D
Sbjct 814 LERNESAVVQLTVQYRMNRKIMSLSNKLTYAGKLECGSDRVANAVLALPNLKDARLSLQL 873
Query 5768 ----------------KSAQCF--KMFYKGVITHDVSSAINRPQIGVVR----EFLTRNP 5805
+ CF + N + ++ F+
Sbjct 874 YADYSDSPWLAGVLEPDNPVCFLNTDKVPAPEQVENGGVSNVTEARLIVFLTSTFIKAGC 933
Query 5806 AWRKAVFISPYNSQNAVASKILG------LPTQTVDSSQGSEYDYVIFTQTTETAHSC-- 5857
+ I+PY Q + S +L + TVD QG + ++ +
Sbjct 934 SPSDIGVIAPYRQQLRIISDLLARSSVGMVEVNTVDKYQGRDKSLILVSFVRSNEDGTLG 993
Query 5858 ----NVNRFNVAITRAKIGILCIMSDR---------DLYDKLQFTSLEIPRRNVATLQAE 5904
+ R NVA+TRAK ++ + S L+D L L + + + + E
Sbjct 994 ELLKDWRRLNVALTRAKHKLILLGSVSSLKRFPPLGTLFDHLNAEQLILD---LPSREHE 1050
Query 5905 NVTGLFKDCSK 5915
+++ + DC +
Sbjct 1051 SLSHILGDCQR 1061
>sp|Q8PHB6|Y3343_XANAC Macro domain-containing protein XAC3343
OS=Xanthomonas axonopodis pv. citri (strain 306) OX=190486
GN=XAC3343 PE=4 SV=2
Length=179
Score = 120 bits (300), Expect = 6e-29, Method: Composition-based stats.
Identities = 37/145 (26%), Positives = 61/145 (42%), Gaps = 15/145 (10%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDY--IKLNG 1073
+ + DI + + VIVNAAN L GGGV GA+++A + + + ++
Sbjct 3 IEVWQGDITE----LDVDVIVNAANESLLGGGGVDGAIHRAAGPRLLEACEALPQVRPGV 58
Query 1074 PLTVGGSCLLSGHNL-AKKCLHVVGPNLNAG---EDIQLLKAAYENFN-----SQDILLA 1124
G + G +L A+ H VGP G E QL +++ +
Sbjct 59 RCPTGEIRITDGFDLKARHIFHTVGPVWRDGRHNEPEQLANCYWQSLKLAEQMMLHSIAF 118
Query 1125 PLLSAGIFGAKPLQSLQVCVQTVRT 1149
P +S GI+G Q+ ++ V R
Sbjct 119 PAISCGIYGYPLHQAARIAVTETRD 143
>sp|Q8Y2K1|Y334_RALN1 Macro domain-containing protein RSc0334
OS=Ralstonia nicotianae (strain GMI1000) OX=267608 GN=RSc0334
PE=4 SV=1
Length=171
Score = 120 bits (300), Expect = 6e-29, Method: Composition-based stats.
Identities = 39/126 (31%), Positives = 59/126 (47%), Gaps = 13/126 (10%)
Query 1033 MVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKK 1091
IVNAAN L GGGV GA+++A + + L+G G + + G L A+
Sbjct 21 DAIVNAANSALLGGGGVDGAIHRAAGPELLEAC---RALHG-CRTGQAKITPGFLLPARY 76
Query 1092 CLHVVGPNLNAG--EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVC 1143
+H VGP G ++ LL A Y N + + P +S G++G P + +
Sbjct 77 IIHTVGPIWRGGRQDEAALLAACYRNSLALAKQHDVRTIAFPCISTGVYGFPPQLAAPIA 136
Query 1144 VQTVRT 1149
V+TVR
Sbjct 137 VRTVRE 142
>sp|Q8IXQ6|PARP9_HUMAN Protein mono-ADP-ribosyltransferase PARP9
OS=Homo sapiens OX=9606 GN=PARP9 PE=1 SV=2
Length=854
Score = 132 bits (331), Expect = 6e-29, Method: Composition-based stats.
Identities = 46/168 (27%), Positives = 74/168 (44%), Gaps = 19/168 (11%)
Query 1033 MVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKK 1091
+VNAAN L HGGG+A AL KA +Q+ES ++ G ++ G + L K+
Sbjct 133 DAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEIAVTGAGRLPCKQ 192
Query 1092 CLHVVGPN---LNAGEDIQLLKAA---------YENFNSQDILLAPLLSAGIFGAKPLQS 1139
+H VGP + L+ A Y+N + + + P LS+GIF
Sbjct 193 IIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIK-TVAIPALSSGIFQFP---- 247
Query 1140 LQVCVQTVRTQVYIAVNDKALYEQVVMDYL-DNLKPRVEAPKQEEPPN 1186
L +C +T+ + +++ K + + +L N P V A K
Sbjct 248 LNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFI 295
Score = 42.7 bits (99), Expect = 0.15, Method: Composition-based stats.
Identities = 26/124 (21%), Positives = 41/124 (33%), Gaps = 10/124 (8%)
Query 1031 NPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-A 1089
VIVN+ N H G VA ++ + M+ E K + G NL
Sbjct 330 TADVIVNSVNPHDITVGPVAKSILQQAGVEMKSE-FLATKAKQFQRSQLVLVTKGFNLFC 388
Query 1090 KKCLHVV------GPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKPLQSLQVC 1143
K HV+ P + + L+ E + + P L G K + ++
Sbjct 389 KYIYHVLWHSEFPKPQILKHAMKECLEKCIEQ--NITSISFPALGTGNMEIKKETAAEIL 446
Query 1144 VQTV 1147
V
Sbjct 447 FDEV 450
>sp|Q7MTZ7|MACRO_PORGI Macro domain-containing protein PG1779
OS=Porphyromonas gingivalis (strain ATCC BAA-308 / W83) OX=242619
GN=PG_1779 PE=2 SV=1
Length=164
Score = 119 bits (299), Expect = 6e-29, Method: Composition-based stats.
Identities = 44/163 (27%), Positives = 70/163 (43%), Gaps = 24/163 (15%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPL 1075
+ I DI + IVNAAN L GGGV GA+++A + +E LNG
Sbjct 4 ITITVGDITR----FEGDAIVNAANHTLLGGGGVDGAIHRAAGPELLEECRT---LNG-C 55
Query 1076 TVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYEN------FNSQDILLAPL 1126
G S + G+NL A+ +H VGP + G+ + +LL + Y + P
Sbjct 56 PTGESKITGGYNLPAQYVIHTVGPVWHGGQHGEPELLASCYRTSLSIALDKGLKSIAFPC 115
Query 1127 LSAGIFGAKPLQSLQVCVQTVRT-------QVYIAVNDKALYE 1162
+S G++ Q+ ++ + T+ V I +A E
Sbjct 116 ISTGVYRYPKDQAARIALATIGEIIADRPIDVTIVCFSEADKE 158
>sp|Q8P5Z8|Y3184_XANCP Macro domain-containing protein XCC3184
OS=Xanthomonas campestris pv. campestris (strain ATCC 33913
/ DSM 3586 / NCPPB 528 / LMG 568 / P 25) OX=190485 GN=XCC3184
PE=4 SV=1
Length=179
Score = 119 bits (299), Expect = 8e-29, Method: Composition-based stats.
Identities = 37/145 (26%), Positives = 61/145 (42%), Gaps = 15/145 (10%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDY--IKLNG 1073
+ + DI + + VIVNAAN L GGGV GA+++A + + + ++
Sbjct 3 IEVWQGDITQ----LDVDVIVNAANESLLGGGGVDGAIHRAAGPRLLEACEALPEVRPGV 58
Query 1074 PLTVGGSCLLSGHNL-AKKCLHVVGPNLNAG---EDIQLLKAAYENFN-----SQDILLA 1124
G + G +L A+ H VGP G E QL +++ +
Sbjct 59 RCPTGEIRITDGFDLKARHIFHTVGPVWRDGKHNEPEQLANCYWQSLKLAEQMMLHSIAF 118
Query 1125 PLLSAGIFGAKPLQSLQVCVQTVRT 1149
P +S GI+G Q+ ++ V R
Sbjct 119 PAISCGIYGYPLYQAARIAVTETRD 143
>sp|Q926Y8|Y2902_LISIN Macro domain-containing protein lin2902
OS=Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP
11262) OX=272626 GN=lin2902 PE=4 SV=1
Length=176
Score = 119 bits (299), Expect = 9e-29, Method: Composition-based stats.
Identities = 44/173 (25%), Positives = 72/173 (42%), Gaps = 15/173 (9%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
++ + DI ++ N VIVNAAN L GGGV GA+++A + KE + I G
Sbjct 2 DITVVKGDITEQ----NVDVIVNAANPGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGS 57
Query 1075 LTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAY------ENFNSQDILLAP 1125
G + + S +L A +H VGP GE + L + Y + P
Sbjct 58 CPAGEAVITSAGDLKAHFIIHAVGPIWKDGEHQEANKLASCYWKALDLAAGKDLTSIAFP 117
Query 1126 LLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
+S G++G + +V + TVR + + ++V D +
Sbjct 118 NISTGVYGFPKKLAAEVALYTVRKWAEEEYD--SSIKEVRFVCFDEENLTLYN 168
>sp|Q71W03|Y2748_LISMF Macro domain-containing protein LMOf2365_2748
OS=Listeria monocytogenes serotype 4b (strain F2365)
OX=265669 GN=LMOf2365_2748 PE=4 SV=1
Length=176
Score = 119 bits (298), Expect = 1e-28, Method: Composition-based stats.
Identities = 43/173 (25%), Positives = 71/173 (41%), Gaps = 15/173 (9%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
+ + DI ++ + VIVNAAN L GGGV GA+++A + KE + I G
Sbjct 2 EITVVKGDITEQ----DVDVIVNAANPGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGT 57
Query 1075 LTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAY------ENFNSQDILLAP 1125
G + + S +L A +H VGP GE + L + Y + P
Sbjct 58 CPAGEAVITSAGDLQASYIIHAVGPIWKDGEHQEANKLASCYWKALDLAAGKELTSIAFP 117
Query 1126 LLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
+S G++G + +V + TVR + E++ D ++
Sbjct 118 NISTGVYGFPKKLAAEVALYTVRKWAEEEYDTS--IEEIRFVCFDEENLKLYN 168
>sp|Q8Y3S3|Y2759_LISMO Macro domain-containing protein lmo2759
OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679
/ EGD-e) OX=169963 GN=lmo2759 PE=4 SV=1
Length=176
Score = 119 bits (298), Expect = 1e-28, Method: Composition-based stats.
Identities = 45/173 (26%), Positives = 71/173 (41%), Gaps = 15/173 (9%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
+ I DI ++ VIVNAAN L GGGV GA+++A + KE + I G
Sbjct 2 EITIVKGDITEQE----VDVIVNAANSGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGS 57
Query 1075 LTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAY------ENFNSQDILLAP 1125
G + + S +L A +H VGP GE + L + Y + P
Sbjct 58 CPAGEAVITSAGDLKATYIIHAVGPIWKDGEHQEANKLASCYWKALDLAAGKDLTSIAFP 117
Query 1126 LLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEA 1178
+S G++G + +V + TVR D ++ E + D ++
Sbjct 118 NISTGVYGFPKKLAAEVALYTVRKWAEEE-YDTSIKE-IRFVCFDEENLKLYN 168
>sp|Q9HXU7|Y3693_PSEAE Macro domain-containing protein PA3693
OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP
104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964
GN=PA3693 PE=4 SV=1
Length=173
Score = 119 bits (297), Expect = 1e-28, Method: Composition-based stats.
Identities = 47/179 (26%), Positives = 75/179 (42%), Gaps = 20/179 (11%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
V + DI + A IVNAAN L GGGV GA+++A + L+G
Sbjct 3 EVRVWQGDITRLA----VDAIVNAANSSLLGGGGVDGAIHRAAGAELVAAC---RLLHG- 54
Query 1075 LTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENFNS------QDILLAP 1125
G + + G L A +H VGP G+ + +LL + Y + + P
Sbjct 55 CKTGEAKITRGFRLPAAHVIHTVGPVWRGGDNGEAELLASCYRRSLALAEQAGAASVAFP 114
Query 1126 LLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEP 1184
+S GI+G Q+ + V+ V Q +L E V++ + ++ R + E P
Sbjct 115 AISCGIYGYPLEQAAAIAVEEVCRQRPAHS---SLEEIVLVAFDSSMAERYQRLLGERP 170
>sp|Q9BXT6|M10L1_HUMAN RNA helicase Mov10l1 OS=Homo sapiens OX=9606
GN=MOV10L1 PE=1 SV=1
Length=1211
Score = 131 bits (330), Expect = 2e-28, Method: Composition-based stats.
Identities = 77/424 (18%), Positives = 133/424 (31%), Gaps = 97/424 (23%)
Query 5583 GPPGTGKS----HFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS------ 5632
GPPGTGK+ + + P +RI+ A S++A D +C + + + +
Sbjct 770 GPPGTGKTVTIIEAVLQVHFALPDSRILVCAPSNSAADLVCLRLHESKVLQPATMVRVNA 829
Query 5633 -----RIIPARARVECFDK---FKVNSTLEQYVFCTVNAL------PETTADIVVFDEIS 5678
I+ + C D +K + C+ + L V DE
Sbjct 830 TCRFEEIVIDAVKPYCRDGEDIWKASRFRIIITTCSSSGLFYQIGVRVGHFTHVFVDEAG 889
Query 5679 MATNYDLSVVNARLR--AKHYVYIGDPAQLP-------APRTLLTKGTLEPEYFNSVCRL 5729
A+ + + + + V GDP QL A L LE +
Sbjct 890 QASEPECLIPLGLMSDISGQIVLAGDPMQLGPVIKSRLAMAYGLNVSFLERLMSRPAYQR 949
Query 5730 MKTI-------GPDMF--LGTCRRCPAEIVDTVSALVYDNKLKAHKDKS----------- 5769
+ P + L R ++ S L Y +L+ D +
Sbjct 950 DENAFGACGAHNPLLVTKLVKNYRSHEALLMLPSRLFYHRELEVCADPTVVTSLLGWEKL 1009
Query 5770 -AQCFKMFYKGVITHDVS-----SAINRPQIGVVREF-------LTRNPAWRKAVFISPY 5816
+ F + + GV + S N + V + ++ + I+PY
Sbjct 1010 PKKGFPLIFHGVRGSEAREGKSPSWFNPAEAVQVLRYCCLLAHSISSQVSASDIGVITPY 1069
Query 5817 NSQNAVAS------KILGLPTQTVDSSQGSEYDYVIFTQTTET-----------AHSCNV 5859
Q ++ + +V+ QG EY +I + N
Sbjct 1070 RKQVEKIRILLRNVDLMDIKVGSVEEFQGQEYLVIIISTVRSNEDRFEDDRYFLGFLSNS 1129
Query 5860 NRFNVAITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITG 5919
RFNVAITR K +L ++ + + L A L+ G++ C
Sbjct 1130 KRFNVAITRPK-ALLIVLGNPHV--------LVRDPCFGALLEYSITNGVYMGC-----D 1175
Query 5920 LHPT 5923
L P
Sbjct 1176 LPPA 1179
>sp|Q1LXK5|M10B2_DANRE Putative helicase mov-10-B.2 OS=Danio rerio
OX=7955 GN=mov10b.2 PE=3 SV=1
Length=1015
Score = 131 bits (329), Expect = 2e-28, Method: Composition-based stats.
Identities = 93/463 (20%), Positives = 148/463 (32%), Gaps = 121/463 (26%)
Query 5525 YFVLTSHTVMPLSAPTL--------VPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQ 5576
F + S ++ P+S P L + Y + + + +
Sbjct 505 LFPMASRSLNPVSPPALRLFDRKLEYNFQQYSAVCNIVAGTSKPAPY------------- 551
Query 5577 KYSTLQGPPGTGKSHFAI----GLALYYPSARIVYTACSHAAVDALCEK--------ALK 5624
+ GPPGTGK+ + + P A I+ A S++A D LCEK A K
Sbjct 552 ---LVFGPPGTGKTVTIVEAIKQVEKNIPDAYILACAPSNSAADQLCEKLITSEHVDAHK 608
Query 5625 YLPIDKCSRI---IPARARVECFDK-----FKVNSTLEQY--VFCTV--------NALPE 5666
+ SR IP + C F L Y + CT+ E
Sbjct 609 IYRLYASSRNQKDIPKILKDNCNVDEEMIDFPCKEDLMSYKILICTLVTAGRLVTGGFSE 668
Query 5667 TTADIVVFDEISMATNYDLSVVNARL---RAKHYVYIGDPAQLP-------APRTLLTKG 5716
DE A + + A L V GDP QL A L
Sbjct 669 DHFTHNFVDEAGHAVESETIISVAGLLNAEKGQLVLAGDPKQLGPILRSPLAINHGLDVS 728
Query 5717 TLEPEYF-NSVCRLMKTIGPDMFLGTC---RRCPAEIVDTVSALVYDNKLKAHKDK---S 5769
LE N + + + ++ R I++ + L YD +LKA D+ +
Sbjct 729 LLERLMTQNDLYKRGDVEFDNRYVSKLIMNYRSHPYILEVPNRLFYDGELKACADEISSN 788
Query 5770 AQC---------FKMFYKGVITHDVS-----SAINRPQIGVVREFLTRN----PAW---- 5807
C F + + GV D S N +I ++ ++L + P
Sbjct 789 QYCMWEHLPSKGFPVIFHGVPGKDERESNSPSFFNIYEINILVDYLKKLLLTQPKKGISR 848
Query 5808 ---RKAVFISPYNSQNAVASKILG-------------LPTQTVDSSQGSEYDYVIFTQTT 5851
+ I+PY Q + + L +V+ QG E ++ +
Sbjct 849 IFPKDIGIIAPYRKQVEKIKRAIDADKDFQDYMGIDNLKVGSVEEFQGQERKVIMVSTVR 908
Query 5852 ------------ETAHSCNVNRFNVAITRAKIGILCIMSDRDL 5882
N RFNVA+TRAK ++ + + L
Sbjct 909 SSVKYISLDETFNIGFLKNEKRFNVAVTRAKSLLIMVGNPMIL 951
>sp|Q8CAS9|PARP9_MOUSE Protein mono-ADP-ribosyltransferase PARP9
OS=Mus musculus OX=10090 GN=Parp9 PE=1 SV=2
Length=866
Score = 130 bits (327), Expect = 2e-28, Method: Composition-based stats.
Identities = 48/162 (30%), Positives = 71/162 (44%), Gaps = 17/162 (10%)
Query 1033 MVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKK 1091
+VNAAN +L HG G+AG+L K +Q+ES I G ++VGG + L
Sbjct 135 DAVVNAANENLLHGSGLAGSLVKTGGFEIQEESKRIIANVGKISVGGIAITGAGRLPCHL 194
Query 1092 CLHVVGPNL---NAGEDIQLLKAAYENFNSQ--------DILLAPLLSAGIFGAKPLQSL 1140
+H VGP N+ I+LLK A N + P LS+GIF L
Sbjct 195 IIHAVGPRWTVTNSQTAIELLKFAIRNILDYVTKYDLRIKTVAIPALSSGIFQFP----L 250
Query 1141 QVCVQTVRTQVYIAVNDKALYEQVVMDYL-DNLKPRVEAPKQ 1181
+C + + + DK ++ + +L N P V + K
Sbjct 251 DLCTSIILETIRLYFQDKQMFGNLREIHLVSNEDPTVASFKS 292
>sp|Q9FJR0|RENT1_ARATH Regulator of nonsense transcripts 1 homolog
OS=Arabidopsis thaliana OX=3702 GN=UPF1 PE=1 SV=2
Length=1254
Score = 131 bits (329), Expect = 2e-28, Method: Composition-based stats.
Identities = 81/419 (19%), Positives = 138/419 (33%), Gaps = 100/419 (24%)
Query 5559 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSAR-----IVYTACSHA 5613
+ + +S V + V + S +QGPPGTGK+ A+ Y A+ ++ A S+
Sbjct 486 LPELNASQVNAVKSVLQKPISLIQGPPGTGKT--VTSAAIVYHMAKQGQGQVLVCAPSNV 543
Query 5614 AVDAL--------------CEKALKYLPIDK----------------------------- 5630
AVD L C K+ + +
Sbjct 544 AVDQLAEKISATGLKVVRLCAKSREAVSSPVEYLTLHYQVRHLDTSEKSELHKLQQLKDE 603
Query 5631 ----CSRIIPARARVECFDKFKVNSTLEQYVFCTVNA----LPETTADIVVFDEISMATN 5682
S ++ + ++ + + V A L V+ DE + AT
Sbjct 604 QGELSSSDEKKYKNLKRATEREITQSADVICCTCVGAADLRLSNFRFRQVLIDESTQATE 663
Query 5683 YDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPD-MFLGT 5741
+ ++ L K V +GD QL ++ K S+ + T+G + L
Sbjct 664 PEC-LIPLVLGVKQVVLVGDHCQLGP--VIMCKKAARAGLAQSLFERLVTLGIKPIRLQV 720
Query 5742 CRRCPAEIVDTVSALVYDNKLK---------------AHKDKSAQCFKMFYKGVITHDVS 5786
R + + S Y+ L+ + F G S
Sbjct 721 QYRMHPALSEFPSNSFYEGTLQNGVTIIERQTTGIDFPWPVPNRPMFFYVQLGQEEISAS 780
Query 5787 --SAINRPQIGVVREFLTRNPAW----RKAVFISPYNSQNAVASKILG------------ 5828
S +NR + V + +T + I+PY Q A +
Sbjct 781 GTSYLNRTEAANVEKLVTAFLKSGVVPSQIGVITPYEGQRAYIVNYMARNGSLRQQLYKE 840
Query 5829 LPTQTVDSSQGSEYDYVIFTQTTETAH-----SCNVNRFNVAITRAKIGILCIMSDRDL 5882
+ +VDS QG E DY+I + H + R NVA+TRA+ GI+ + + + L
Sbjct 841 IEVASVDSFQGREKDYIILSCVRSNEHQGIGFLNDPRRLNVALTRARYGIVILGNPKVL 899
>sp|Q93SX7|Y189_ACISE Macro domain-containing protein OS=Acinetobacter
sp. (strain ED45-25) OX=194927 PE=4 SV=1
Length=183
Score = 118 bits (296), Expect = 3e-28, Method: Composition-based stats.
Identities = 42/181 (23%), Positives = 77/181 (43%), Gaps = 24/181 (13%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPL 1075
V + DI A A IVN+AN L GGG+ ++K M++E + G
Sbjct 4 VHLIQADITAFAVHA----IVNSANKSLLGGGGLDYVIHKKAGPLMKEECVRLNQEKGGC 59
Query 1076 TVGGSCLLSGHNL-AKKCLHVVGPNL--NAGEDIQLLKAAYENFNSQD------ILLAPL 1126
G + + + NL AK +H VGP + QLL AY N + + P
Sbjct 60 PTGQAEVTTAGNLPAKYLIHAVGPRWLDGEHNEPQLLCDAYSNALFKANEIHALTVSFPC 119
Query 1127 LSAGIFGAKPLQSLQVCVQTVRT---------QVYIAVNDKA--LYEQVVMDYLDNLKPR 1175
+S G++G P ++ ++ + T+ + +V+ + L + ++ +D+ +
Sbjct 120 ISTGVYGFPPQKAAEIAIGTILSMLPQYDHVAEVFFICREDENYLIYKNILSNIDDPNIQ 179
Query 1176 V 1176
+
Sbjct 180 I 180
>sp|O76512|RENT1_CAEEL Regulator of nonsense transcripts 1 OS=Caenorhabditis
elegans OX=6239 GN=smg-2 PE=1 SV=1
Length=1069
Score = 130 bits (326), Expect = 3e-28, Method: Composition-based stats.
Identities = 81/415 (20%), Positives = 139/415 (33%), Gaps = 95/415 (23%)
Query 5559 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAA 5614
+ + SS + ++V + S +QGPPGTGK+ L ++ + S+ A
Sbjct 443 LPELNSSQMQAVKQVLTRPLSLIQGPPGTGKTVVSATIVYHLVQKTEGN-VLVCSPSNIA 501
Query 5615 VDALCEKALK--YLPIDKCSRIIPARARVECFD--------------------------- 5645
VD L EK K + C+R +
Sbjct 502 VDHLAEKIHKTGLKVVRLCARSREHSETTVPYLTLQHQLKVMGGAELQKLIQLKDEAGEL 561
Query 5646 KFKVNSTLEQ--------------YVFCTVNA-----LPETTADIVVFDEISMATNYDLS 5686
+FK + Q + CT ++ L + V+ DE + AT ++
Sbjct 562 EFKDDLRYMQLKRVKEHELLAAADVICCTCSSAADARLSKIRTRTVLIDESTQATEPEIL 621
Query 5687 VVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMF-LGTCRRC 5745
V R + V +GD QL ++ K S+ + +G F L R
Sbjct 622 VSIMR-GVRQLVLVGDHCQLGP--VVICKKAAIAGLSQSLFERLVLLGIRPFRLQVQYRM 678
Query 5746 PAEIVDTVSALVYDNKLKAHKDKSAQ---------------CFKMFYKGVITHDVS--SA 5788
+ + S + YD L+ ++ + F G S S
Sbjct 679 HPVLSEFPSNVFYDGSLQNGVTENDRHMTGVDWHWPKPNKPAFFWHCSGSEELSASGTSF 738
Query 5789 INRPQI----GVVREFLTRNPAWRKAVFISPYNSQNAVASKIL------------GLPTQ 5832
+NR + +V + + + I+ Y Q + + +
Sbjct 739 LNRTEAANVEKLVSKLIKAGVQPHQIGVITSYEGQRSFIVNYMHTQGTLNSKLYENVEIA 798
Query 5833 TVDSSQGSEYDYVIFTQTTE-----TAHSCNVNRFNVAITRAKIGILCIMSDRDL 5882
+VD+ QG E DY+I T + R NVAITRAK G++ + + + L
Sbjct 799 SVDAFQGREKDYIIVTCVRSNDILGIGFLSDPRRLNVAITRAKYGLVLVGNAKVL 853
>sp|Q8RHQ2|Y1951_FUSNN Uncharacterized protein FN1951 OS=Fusobacterium
nucleatum subsp. nucleatum (strain ATCC 25586 / DSM
15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG
13131 / VPI 4355) OX=190304 GN=FN1951 PE=4 SV=1
Length=175
Score = 117 bits (294), Expect = 4e-28, Method: Composition-based stats.
Identities = 46/179 (26%), Positives = 76/179 (42%), Gaps = 20/179 (11%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPL 1075
+ + DI K + IVNAAN L+ GGGV GA+ KA + +E + G
Sbjct 6 IKLISGDITKIPEV---EAIVNAANSSLEMGGGVCGAIFKAAGSELAQECKEI----GGC 58
Query 1076 TVGGSCLLSGHNLA-KKCLHVVGPNLNAG---EDIQLLKAAYENF---NSQDI--LLAPL 1126
G + + G+NL K +H VGP + G E +L A YE+ N + I + P
Sbjct 59 NTGEAVITKGYNLPNKYIIHTVGPRYSTGENREAERLASAYYESLKLANEKGIRRIAFPS 118
Query 1127 LSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPP 1185
+S GI+ + ++ + T ++ +++ LD V K ++
Sbjct 119 ISTGIYRFPVDEGAKIAL----TTAIKFLDKNPSSFDLILWVLDEKTYIVYKEKYKKLL 173
>sp|Q8TQD0|Y1614_METAC Macro domain-containing protein MA_1614
OS=Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834
/ JCM 12185 / C2A) OX=188937 GN=MA_1614 PE=4 SV=1
Length=195
Score = 118 bits (296), Expect = 4e-28, Method: Composition-based stats.
Identities = 40/155 (26%), Positives = 66/155 (43%), Gaps = 22/155 (14%)
Query 1023 IVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCL 1082
I ++ IVNAAN L GGGV GA+++A + +E LNG G + +
Sbjct 32 IERDITELKVDAIVNAANNTLLGGGGVDGAIHRAAGPGLLEECRT---LNG-CPTGEAKI 87
Query 1083 LSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYEN----FNSQDI--LLAPLLSAGIFG 1133
G+ L AK +H VGP G + + L + Y D+ + P +S G +G
Sbjct 88 TKGYLLPAKYVIHTVGPIWQEGTKGEDEFLASCYRKSLELARKYDVKTIAFPTISTGAYG 147
Query 1134 AKPLQSLQVCVQTVR---------TQVYIAVNDKA 1159
++ ++ V V+ V++ +K
Sbjct 148 FPSERAARIAVSQVKEFLKVNELPEIVFLVCYNKE 182
>sp|Q0V8H6|MOV10_BOVIN Putative helicase MOV-10 OS=Bos taurus
OX=9913 GN=MOV10 PE=2 SV=1
Length=1003
Score = 130 bits (326), Expect = 4e-28, Method: Composition-based stats.
Identities = 86/401 (21%), Positives = 131/401 (33%), Gaps = 103/401 (26%)
Query 5581 LQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPID------- 5629
+ GPPGTGK+ + + P A I+ A S++ D LC++ +LP
Sbjct 522 IFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAP 581
Query 5630 -KCSRIIPARARVEC----------FDKFKVNSTLEQYVFCTVNA-------LPETTADI 5671
+ ++P + C F K + + A P
Sbjct 582 SRDIHLVPEDIKPCCNWDAKKGDFVFPSKKKLQEYRVLITTLITASRLVSAQFPIDHFTH 641
Query 5672 VVFDEISMATNYDLSVVNARLR--------AKHYVYIGDPAQL-PAPRTLLT-KGTLEPE 5721
+ DE A + V A L V GDP QL P R LT K L
Sbjct 642 IFIDEAGHAMEPESLVAIAGLMEVKEADNPGGQLVLAGDPRQLGPVLRCPLTQKHGLGYS 701
Query 5722 ------YFNSVCRLMKTIGPDMFLGTC---RRCPAEIVDTVSALVYDNKLKAHKDKSA-- 5770
FN++ + F+ R I+D + L YD +L+A D
Sbjct 702 LLERLLTFNALYKKGPDGYNPQFITKLLRNYRSHPTILDVPNRLYYDGELQACADVVDRE 761
Query 5771 ----------QCFKMFYKGVITHDVS-----SAINRPQIGVVREFLTRN--PAWRKA--- 5810
Q F + + GV+ D S N + V +L + P+ +K
Sbjct 762 RFCRWEGLPRQDFPIIFHGVMGKDEREGNSPSFFNPEEAATVTSYLKQLLAPSSKKGKAR 821
Query 5811 ------VFISPYNSQNAVAS--------------KILGLPTQTVDSSQGSEYDYVIFTQT 5850
ISPY Q I L +V+ QG E ++ +
Sbjct 822 LSPRSVGVISPYRKQVEKIRYCITKLDKQLRGLDDIKDLKVGSVEEFQGQERSVILISTV 881
Query 5851 TETA------------HSCNVNRFNVAITRAKIGILCIMSD 5879
+ N RFNVA+TRAK +L ++ +
Sbjct 882 RSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAK-ALLIVVGN 921
>sp|Q5ZKD7|MOV10_CHICK Putative helicase MOV-10 OS=Gallus gallus
OX=9031 GN=MOV10 PE=2 SV=1
Length=967
Score = 129 bits (325), Expect = 4e-28, Method: Composition-based stats.
Identities = 91/421 (22%), Positives = 139/421 (33%), Gaps = 110/421 (26%)
Query 5574 GMQKYS--TLQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLP 5627
GM + + + GPPGTGK+ + + ARI+ A S++A D LC++ L +
Sbjct 505 GMSRPAPYLIFGPPGTGKTVTLVEAIKQVWSCFKDARILACAPSNSAADLLCQRLLTNIA 564
Query 5628 IDKCSRI---------IPARARVEC----------FDKFKVNSTLEQYVFCTVNA----- 5663
RI +PA R C + K+ + V A
Sbjct 565 PRYIYRIMASSANYKDVPADVRPCCNWDDSEKCYVYPSKKLLKPYRILITTLVTAGRLVS 624
Query 5664 --LPETTADIVVFDEISMATNYDLSVVNARL----------RAKHYVYIGDPAQL-PAPR 5710
P V DE A + V A L V GDP QL P PR
Sbjct 625 ANFPPGYFSHVFIDECGHAVEPESVVAIAGLLTTMDPDTNPNGGQLVLAGDPQQLGPVPR 684
Query 5711 T------LLTKGTLEP-EYFNSVCRLMKTIGPDMFLGTC---RRCPAEIVDTVSALVYDN 5760
+ L LE N++ F+ R I+ + L YD+
Sbjct 685 SPLAAQHGLGTSLLERLMLHNALYAKSDEGYNPQFVTKLLWNYRSHKAILKVPNELFYDS 744
Query 5761 KLKAH--KDKSAQCF------------KMFYKGVITHDVS-----SAINRPQIGVVREFL 5801
+LKA+ + + F + + GV D S N +I VV ++L
Sbjct 745 ELKAYEGSEPDVRNFYCTWEELPNRGVPIIFHGVCGEDEREAKSPSFFNTAEIEVVVQYL 804
Query 5802 TRNPAW-----------RKAVFISPYNSQNAVASKILG--------------LPTQTVDS 5836
+ ++ ISPY Q + L +V+
Sbjct 805 QKLLQSQGRRGCPTISPKEIGIISPYRKQVEKIRLAITSKDPVLRALPDIGQLKVGSVEE 864
Query 5837 SQGSEYDYVIFT------------QTTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYD 5884
QG E ++ + QT N R NVA+TRAK +L ++ + +
Sbjct 865 FQGQERRVILISTVRSCSEYLQLDQTFRLGFLKNPKRLNVALTRAK-ALLIVVGNAAVLS 923
Query 5885 K 5885
K
Sbjct 924 K 924
>sp|Q8QHA5|DNA2_XENLA DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Xenopus laevis OX=8355 GN=dna2 PE=1 SV=1
Length=1053
Score = 129 bits (323), Expect = 8e-28, Method: Composition-based stats.
Identities = 75/393 (19%), Positives = 128/393 (33%), Gaps = 87/393 (22%)
Query 5576 QKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKALKY----LPID 5629
+ Y+ + G PGTGK+ + LY ++ T+ +H+AVD + K K+ L +
Sbjct 642 KDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLKKFQVGFLRLG 701
Query 5630 KCSRIIP-----ARARVECFDKFKV--------NSTLEQYVFC---TVNALPETTADIVV 5673
+ ++ P + + K NS C D +
Sbjct 702 RTQKLHPDVQEFSEEEICKAKSIKSLSALEELYNSQPVVATTCMGVNHPIFTRRRFDFCI 761
Query 5674 FDEISMATNYDLSVVNARLR-AKHYVYIGDPAQLPA--PRTLLTKGTLEPEYFNSVCRLM 5730
DE S + + L A +V +GD QLP + + F RL
Sbjct 762 VDEASQISQ---PICLGPLFFADRFVLVGDHQQLPPLVKSAEARELGMSESLFK---RLE 815
Query 5731 KTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD----------------------- 5767
+ + L R ++I+ + LVY+ +L+ D
Sbjct 816 RNQEAVVQLTVQYRMNSKIMALSNKLVYEGRLECASDRVSNAVVQLPHIKTLLLELEFRE 875
Query 5768 -------------KSAQCFKMFYK--GVITHDVSSAINRPQIGVV----REFLTRNPAWR 5808
+ CF K + T + N + +V + +L
Sbjct 876 SQESMWIKDVLEPSNPVCFLNTEKIPALETEEKGGISNWIEAKLVFHLTKLYLKAGCRPS 935
Query 5809 KAVFISPYNSQ-----NAVAS-KILGLPTQTVDSSQGSEYDYVIFTQTTET------AHS 5856
I+PY Q N S + TVD QG + +I +
Sbjct 936 DIGIIAPYRQQLKMISNYFNSLSASAVEVNTVDKYQGRDKSVIIVSFVRSNIDGKLGDLL 995
Query 5857 CNVNRFNVAITRAKIGILCIMSDRDL--YDKLQ 5887
+ R NVA+TRAK ++ + L +D L+
Sbjct 996 KDWRRLNVALTRAKHKLIMLGCVPTLNRFDCLE 1028
>sp|Q54I89|RENT1_DICDI Regulator of nonsense transcripts 1 OS=Dictyostelium
discoideum OX=44689 GN=upf1 PE=3 SV=1
Length=1331
Score = 129 bits (324), Expect = 9e-28, Method: Composition-based stats.
Identities = 92/482 (19%), Positives = 171/482 (35%), Gaps = 106/482 (22%)
Query 5503 KGDYGDAVVYRGTTTYKLNVGD-YFVLTSHTVMP------LSAPTLVPQEHYVRITGLYP 5555
KG Y +V+R T++ ++ F + + L P + P +++ +
Sbjct 471 KGSYRMEMVWRSTSSERILSAMKSFAIKEQALSSYLYHALLGHPDIPPAPLDIQLPTNFH 530
Query 5556 TLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS---HFAIG-LALYYPSA-RIVYTAC 5610
N+ S ++ KV S +QGPPGTGK+ F I L Y +++
Sbjct 531 LKNLPRLNESQISAVNKVLTAPLSLIQGPPGTGKTVISSFIIHHLVKYVKGNDKVLVCTP 590
Query 5611 SHAAV----DALCEKALKYLPIDKCSR---IIPARARVECFDKFKV-------------- 5649
S+ A+ L E LK + + R P +K+
Sbjct 591 SNVAIDQLTGKLHEIGLKVVRLSSKLREEVASPVEHLTLHKQVYKLDQMGDGELGKLRKL 650
Query 5650 --------NSTLEQYVFC-------------TVNALPETTAD---------IVVFDEISM 5679
N ++Y++ + A D ++ DE +
Sbjct 651 KEAFGSLSNEDEKRYIYLRRMMEMAILRKADVICATCVGAGDPRLSQFRFPHILIDESTQ 710
Query 5680 ATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIG--PDM 5737
A+ + ++ + AK + +GD QL LL K ++ S+ + ++G P+
Sbjct 711 ASEPEC-LIPLMMGAKQVILVGDHRQLGP--VLLCKKVVDAGLSQSLFERLISLGHHPER 767
Query 5738 FLGTCRRCPAEIVDTVSALVYDNKLKA---HKDKSAQC--------FKMFYKGVITHDVS 5786
L R + + S Y+ +L + H D+ +Q MF+ +
Sbjct 768 -LTIQYRMHPSLTEFPSNTSYEGQLVSELSHTDRDSQSKFPWPQPKDPMFFFNCTGSEEI 826
Query 5787 SA-----INRPQIGVVREFLTRNPAWRK----AVFISPYNSQNAVASKIL---------- 5827
S+ IN + + + +T+ I+PY Q A + +
Sbjct 827 SSSGTSFINTTEASICEKIVTKFLELGSLPGQIGIITPYEGQRAYITSHMQKSGKLNLEL 886
Query 5828 --GLPTQTVDSSQGSEYDYVIFTQTTE-----TAHSCNVNRFNVAITRAKIGILCIMSDR 5880
+ +VDS QG E DY+I + + R NVA+TRA+ G++ + + +
Sbjct 887 YKSIEVASVDSFQGREKDYIILSCVRSNDYQGIGFLQDPRRLNVALTRARFGLIILGNAK 946
Query 5881 DL 5882
L
Sbjct 947 VL 948
>sp|Q88SK6|Y3408_LACPL Macro domain-containing protein lp_3408
OS=Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB
8826 / WCFS1) OX=220668 GN=lp_3408 PE=4 SV=1
Length=172
Score = 116 bits (290), Expect = 1e-27, Method: Composition-based stats.
Identities = 41/171 (24%), Positives = 69/171 (40%), Gaps = 20/171 (12%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
+ + DI K IVNAAN L GGGV GA+++A A+ L+G
Sbjct 3 EIKVIHGDITK----MTVDAIVNAANTSLLGGGGVDGAIHRAAGPALLAAC---RPLHG- 54
Query 1075 LTVGGSCLLSGHNL-AKKCLHVVGPNLNAG--EDIQLLKAAYENF------NSQDILLAP 1125
G + + G L AK +H GP G ++QLL +Y N N + P
Sbjct 55 CATGEAKITPGFRLPAKYVIHTPGPVWQGGQHNELQLLANSYRNSLNLAAENHCQTVAFP 114
Query 1126 LLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRV 1176
+S G++ + + ++T++ + + + + D+ V
Sbjct 115 SISTGVYHFPLSIAAPLALKTLQATAQTTAHT---VQTITIVCFDDQTQNV 162
>sp|Q460N5|PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14
OS=Homo sapiens OX=9606 GN=PARP14 PE=1 SV=3
Length=1801
Score = 129 bits (324), Expect = 1e-27, Method: Composition-based stats.
Identities = 54/296 (18%), Positives = 99/296 (33%), Gaps = 33/296 (11%)
Query 1026 EAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSG 1085
+ V+VNA+N LKH GG+A AL+KA +Q + D +K G L G + +
Sbjct 810 DLARLPVDVVVNASNEDLKHYGGLAAALSKAAGPELQADCDQIVKREGRLLPGNATISKA 869
Query 1086 HNLA-KKCLHVVGPNLNAGED---------IQLLKAAYENFNSQDILLAPLLSAGIFGAK 1135
L +H VGP + E L + P +S+G+FG
Sbjct 870 GKLPYHHVIHAVGPRWSGYEAPRCVYLLRRAVQLSLCLAEKYKYRSIAIPAISSGVFGFP 929
Query 1136 PLQSLQVCVQTVRTQVYIAVNDKALYE----QVVMDYLDNLKPRVEAPKQEEPPNTEDSK 1191
+ ++ V ++ + L E V ++ V+ + P+T
Sbjct 930 LGRCVETIVSAIKENFQFKKDGHCLKEIYLVDVSEKTVEAFAEAVKTVFKATLPDTAAPP 989
Query 1192 TEEKSVVQKPVDVKPKIKACIDEVTTTL--------EETKFLTNKLLLFADIN----GKL 1239
+ K L +T + N + L ++ K
Sbjct 990 GLPPAAAGPGKTSWEKGSLVSPGGLQMLLVKEGVQNAKTDVVVNSVPLDLVLSRGPLSKS 1049
Query 1240 YHDSQNMLRGEDMSFLEKDAPYMVGDVITSGD-------ITCVVIPSKKAGGTTEM 1288
+ E++ + + +G V+ + + VV P + G T+ +
Sbjct 1050 LLEKAGPELQEELDTVGQGVAVSMGTVLKTSSWNLDCRYVLHVVAPEWRNGSTSSL 1105
Score = 66.6 bits (161), Expect = 1e-08, Method: Composition-based stats.
Identities = 61/419 (15%), Positives = 133/419 (32%), Gaps = 60/419 (14%)
Query 1023 IVKEAQSANPMVIVNAANIHL-KHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSC 1081
+ + Q+A V+VN+ + L G ++ +L + +Q+E D + +++G
Sbjct 1019 VKEGVQNAKTDVVVNSVPLDLVLSRGPLSKSLLEKAGPELQEELDT-VGQGVAVSMGTVL 1077
Query 1082 LLSGHNL-AKKCLHVVGPNLNAGEDIQL--LKAAYENF------NSQDILLAPLLSAGIF 1132
S NL + LHVV P G L ++ S + P + G
Sbjct 1078 KTSSWNLDCRYVLHVVAPEWRNGSTSSLKIMEDIIRECMEITESLSLKSIAFPAIGTGNL 1137
Query 1133 GAKPLQSLQVCVQTVRTQVYIAVNDKALY--EQVVMDYLDNLKPRVEAPKQE-------- 1182
G + + + ++V+ + L ++V + ++A E
Sbjct 1138 GFPK----NIFAELIISEVFKFSSKNQLKTLQEVHFLLHPSDHENIQAFSDEFARRANGN 1193
Query 1183 ----EPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKF--------LTNKLL 1230
+ P +D++ +V V I + + TK +N
Sbjct 1194 LVSDKIPKAKDTQGFYGTVSSPDSGVYEMKIGSIIFQVASGDITKEEADVIVNSTSNSFN 1253
Query 1231 LFADINGKLYHDSQNMLRGE-DMSFLEKDAPYMV--GDVITSGDITCVVIPSKKAGGTTE 1287
L A ++ + + + E ++ Y++ G + +I V+ + +
Sbjct 1254 LKAGVSKAILECAGQNVERECSQQAQQRKNDYIITGGGFLRCKNIIHVIGGNDVKSSVSS 1313
Query 1288 MLSRALKKVPVDEYITTYPGQGCAGYTLEEAKTALKKCKSAFYVLPSEAPNAKEEILGTV 1347
+L KK Y + G + + A I V
Sbjct 1314 VLQECEKK----NYSSICLPAIGTGNAKQHPDKVAEAIIDA--------------IEDFV 1355
Query 1348 SWNLREMLAHAEETRKLMPICMDVRAIMATIQRKYKGIKIQEGIVDYGVRFFFYTSKEP 1406
+ + + L + A M +R+ + Q+ ++ F ++ + P
Sbjct 1356 QKGSAQSVKKVKVVIFLPQVLDVFYANMK--KREGTQLSSQQSVMSKLASFLGFSKQSP 1412
Score = 58.1 bits (139), Expect = 4e-06, Method: Composition-based stats.
Identities = 30/183 (16%), Positives = 59/183 (32%), Gaps = 16/183 (9%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ DI KE VIVN+ + GV+ A+ + +++E +
Sbjct 1231 VASGDITKEE----ADVIVNSTSNSFNLKAGVSKAILECAGQNVERECSQQAQQRKN--- 1283
Query 1078 GGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPLLSAGIFGAKP 1136
+ G L K +HV+G N +L+ + + + P + G P
Sbjct 1284 -DYIITGGGFLRCKNIIHVIGGNDVKSSVSSVLQECEK--KNYSSICLPAIGTGNAKQHP 1340
Query 1137 LQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKS 1196
+ + + + V +VV+ P+V E ++ +
Sbjct 1341 DKVAEAIIDAIEDFVQKGSAQSVKKVKVVI-----FLPQVLDVFYANMKKREGTQLSSQQ 1395
Query 1197 VVQ 1199
V
Sbjct 1396 SVM 1398
>sp|Q985D2|Y7730_RHILO Macro domain-containing protein mll7730
OS=Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 /
MAFF 303099) OX=266835 GN=mll7730 PE=4 SV=1
Length=176
Score = 115 bits (288), Expect = 3e-27, Method: Composition-based stats.
Identities = 48/173 (28%), Positives = 77/173 (45%), Gaps = 21/173 (12%)
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNG 1073
D + I DI K + IVNAAN L GGGV GA+++A ++ E LNG
Sbjct 6 DRIRIHTGDITK----LDVDAIVNAANTLLLGGGGVDGAIHRAAGRELEVEC---RMLNG 58
Query 1074 PLTVGGSCLLSGHNL-AKKCLHVVGPNLNAG--EDIQLLKAAYE------NFNSQDILLA 1124
VG + + G+ L A+ +H VGP G + +LL + Y N +
Sbjct 59 -CKVGDAKITKGYKLPARHIIHTVGPVWQGGGKGEAELLASCYRSSLELAAANDCRSVAF 117
Query 1125 PLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVE 1177
P +S G++ ++ + V TV + + +KA+ E V+ D ++
Sbjct 118 PAISTGVYRYPKDEATGIAVGTVS----MVIEEKAMPETVIFCCFDEQTAQLY 166
>sp|A0A1P8ASY1|JHS1_ARATH DNA replication ATP-dependent helicase/nuclease
JHS1 OS=Arabidopsis thaliana OX=3702 GN=JHS1 PE=2
SV=1
Length=1331
Score = 127 bits (320), Expect = 3e-27, Method: Composition-based stats.
Identities = 89/438 (20%), Positives = 163/438 (37%), Gaps = 75/438 (17%)
Query 5514 GTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNI--SDEFSSN---VA 5568
+ + N+ FV H + + P+ I P ++ S++ +N A
Sbjct 871 SFSVMRFNLMQLFVQNGHNIRKMIVDLEPPRFDNGSILSQDPAISYIWSEKSLNNDQRQA 930
Query 5569 NYQKVGMQKYSTLQGPPGTGKSHFAIG--LALYYPSARIVYTACSHAAVDALCEK----A 5622
+ + + Y+ + G PGTGK+ + AL + I+ + +++AVD L K
Sbjct 931 ILKILTAKDYALILGMPGTGKTSTMVHAVKALLIRGSSILLASYTNSAVDNLLIKLKAQG 990
Query 5623 LKYLPIDKCSRIIPARARVECFD----------KFKVNSTLEQYVFCT-VNA--LPETTA 5669
+++L I + + R CF K K++ C +N+ L
Sbjct 991 IEFLRIGR-DEAVHEEVRESCFSAMNMCSVEDIKKKLDQVKVVASTCLGINSPLLVNRRF 1049
Query 5670 DIVVFDEISMATNYDLSVVNARLR-AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCR 5728
D+ + DE L V L A +V +GD QLP + + E S+ R
Sbjct 1050 DVCIIDEAGQIA---LPVSIGPLLFASTFVLVGDHYQLPP--LVQSTEARENGMGISLFR 1104
Query 5729 LMKTIGPDM--FLGTCRRCPAEIVDTVSALVYDN------------------------KL 5762
+ P L R I++ +AL+Y + L
Sbjct 1105 RLSEAHPQAISVLQNQYRMCRGIMELSNALIYGDRLCCGSAEVADATLVLSTSSSTSPWL 1164
Query 5763 KAHKDKSAQCFKMFYKGVITHDVSS--AINRPQ-----IGVVREFLTRNPAWRKAVFISP 5815
K + + + + + AIN P +V E + + I+P
Sbjct 1165 KKVLEPTRTVVFVNTDMLRAFEARDQNAINNPVEASIIAEIVEELVNNGVDSKDIGIITP 1224
Query 5816 YNSQNAV---ASKILGLPTQTVDSSQGSEYDYVIFT--------QTTETAHSCNVNRFNV 5864
YNSQ ++ A + T+D QG + D ++ + +++ ++ + +R NV
Sbjct 1225 YNSQASLIQHAIPTTPVEIHTIDKYQGRDKDCILVSFVRSREKPRSSASSLLGDWHRINV 1284
Query 5865 AITRAKIGILCIMSDRDL 5882
A+TRAK ++ + S R L
Sbjct 1285 ALTRAKKKLIMVGSQRTL 1302
>sp|Q9EPU0|RENT1_MOUSE Regulator of nonsense transcripts 1 OS=Mus
musculus OX=10090 GN=Upf1 PE=1 SV=2
Length=1124
Score = 127 bits (318), Expect = 3e-27, Method: Composition-based stats.
Identities = 79/416 (19%), Positives = 141/416 (34%), Gaps = 96/416 (23%)
Query 5559 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAA 5614
+ D S V + V + S +QGPPGTGK+ LA + ++ A S+ A
Sbjct 474 LPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLAR-QGNGPVLVCAPSNIA 532
Query 5615 VDAL--------------CEKALKYLPIDKCSRIIPARARV------------------- 5641
VD L C K+ + + + + R
Sbjct 533 VDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGE 592
Query 5642 ------ECFDKFKVNST-----LEQYVFCT-VNA----LPETTADIVVFDEISMATNYDL 5685
+ + K + + CT V A L + ++ DE + AT +
Sbjct 593 LSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPEC 652
Query 5686 SVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIG-PDMFLGTCRR 5744
+V L AK + +GD QL ++ K + S+ + +G + L R
Sbjct 653 -MVPVVLGAKQLILVGDHCQLGP--VVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYR 709
Query 5745 CPAEIVDTVSALVYDNKLKAHKDKSAQC---------------FKMFYKGVITHDVS--S 5787
+ S + Y+ L+ + + F +G S S
Sbjct 710 MHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTS 769
Query 5788 AINRPQIGVVRE----FLTRNPAWRKAVFISPYNSQNAVASKIL------------GLPT 5831
+NR + V + L + I+PY Q + + + +
Sbjct 770 YLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEI 829
Query 5832 QTVDSSQGSEYDYVIFTQTTETAH-----SCNVNRFNVAITRAKIGILCIMSDRDL 5882
+VD+ QG E D++I + H + R NVA+TRA+ G++ + + + L
Sbjct 830 ASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKAL 885
>sp|Q92900|RENT1_HUMAN Regulator of nonsense transcripts 1 OS=Homo
sapiens OX=9606 GN=UPF1 PE=1 SV=2
Length=1129
Score = 127 bits (318), Expect = 3e-27, Method: Composition-based stats.
Identities = 79/416 (19%), Positives = 141/416 (34%), Gaps = 96/416 (23%)
Query 5559 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAA 5614
+ D S V + V + S +QGPPGTGK+ LA + ++ A S+ A
Sbjct 479 LPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLAR-QGNGPVLVCAPSNIA 537
Query 5615 VDAL--------------CEKALKYLPIDKCSRIIPARARV------------------- 5641
VD L C K+ + + + + R
Sbjct 538 VDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGE 597
Query 5642 ------ECFDKFKVNST-----LEQYVFCT-VNA----LPETTADIVVFDEISMATNYDL 5685
+ + K + + CT V A L + ++ DE + AT +
Sbjct 598 LSSADEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPEC 657
Query 5686 SVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIG-PDMFLGTCRR 5744
+V L AK + +GD QL ++ K + S+ + +G + L R
Sbjct 658 -MVPVVLGAKQLILVGDHCQLGP--VVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYR 714
Query 5745 CPAEIVDTVSALVYDNKLKAHKDKSAQC---------------FKMFYKGVITHDVS--S 5787
+ S + Y+ L+ + + F +G S S
Sbjct 715 MHPALSAFPSNIFYEGSLQNGVTAADRVKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTS 774
Query 5788 AINRPQIGVVRE----FLTRNPAWRKAVFISPYNSQNAVASKIL------------GLPT 5831
+NR + V + L + I+PY Q + + + +
Sbjct 775 YLNRTEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEI 834
Query 5832 QTVDSSQGSEYDYVIFTQTTETAH-----SCNVNRFNVAITRAKIGILCIMSDRDL 5882
+VD+ QG E D++I + H + R NVA+TRA+ G++ + + + L
Sbjct 835 ASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKAL 890
>sp|Q9KHE2|Y189_STRGR Macro domain-containing protein in non 5'region
OS=Streptomyces griseus OX=1911 PE=4 SV=1
Length=177
Score = 114 bits (286), Expect = 4e-27, Method: Composition-based stats.
Identities = 38/158 (24%), Positives = 63/158 (40%), Gaps = 14/158 (9%)
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
++ V + DI ++ VIVNAAN L GGGV GA+++ + +
Sbjct 3 TSVSPVVRLVRGDITDQS----VDVIVNAANSSLLGGGGVDGAIHRRGGPDILAACRELR 58
Query 1070 KLN--GPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGED-IQLLKAAYE------NFNSQ 1119
L G + + L A+ +H VGP + +D LL + Y
Sbjct 59 ASRYGKGLPTGQAVATTAGRLDARWIVHTVGPVFSGAQDRSALLASCYRESLRLAAELGA 118
Query 1120 DILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVND 1157
+ P +S GI+G ++ V+TV + V +
Sbjct 119 RSIAFPAISTGIYGWPMDDGARIAVRTVLAETVEPVEE 156
>sp|F1RCY6|RENT1_DANRE Regulator of nonsense transcripts 1 OS=Danio
rerio OX=7955 GN=upf1 PE=2 SV=1
Length=1100
Score = 126 bits (317), Expect = 5e-27, Method: Composition-based stats.
Identities = 79/416 (19%), Positives = 140/416 (34%), Gaps = 96/416 (23%)
Query 5559 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAA 5614
+ D S V + V + S +QGPPGTGK+ LA + ++ A S+ A
Sbjct 448 LPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLAR-QGNGPVLVCAPSNIA 506
Query 5615 VDAL--------------CEKALKYLPIDKCSRIIPARARV------------------- 5641
VD L C K+ + + + + R
Sbjct 507 VDQLTEKIHQTGLKVVRLCAKSREAIDSPVSFLALHNQIRNMDSMPELQKLQQLKDETGE 566
Query 5642 ------ECFDKFKVNST-----LEQYVFCT-VNA----LPETTADIVVFDEISMATNYDL 5685
+ + K + + CT V A L + ++ DE + AT +
Sbjct 567 LSSSDEKRYRALKRTAERELLMNADVICCTCVGAGDPRLAKMQFRSILIDESTQATEPEC 626
Query 5686 SVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIG-PDMFLGTCRR 5744
+V L AK + +GD QL ++ K + S+ + +G + L R
Sbjct 627 -MVPVVLGAKQLILVGDHCQLGP--VVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYR 683
Query 5745 CPAEIVDTVSALVYDNKLKAHKDKSAQC---------------FKMFYKGVITHDVS--S 5787
+ S + Y+ L+ + + F +G S S
Sbjct 684 MHPALSAFPSNIFYEGSLQNGVTAADRLKKGFDFQWPQPDKPMFFYVTQGQEEIASSGTS 743
Query 5788 AINRPQIGVVR----EFLTRNPAWRKAVFISPYNSQNAVASKIL------------GLPT 5831
+NR + V L + I+PY Q + + + +
Sbjct 744 YLNRTEAANVEKITTRLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEI 803
Query 5832 QTVDSSQGSEYDYVIFTQTTETAH-----SCNVNRFNVAITRAKIGILCIMSDRDL 5882
+VD+ QG E D++I + H + R NVA+TRA+ G++ + + + L
Sbjct 804 ASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKAL 859
>sp|Q9ZBG3|Y6450_STRCO Macro domain-containing protein SCO6450
OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
OX=100226 GN=SCO6450 PE=4 SV=1
Length=169
Score = 114 bits (285), Expect = 5e-27, Method: Composition-based stats.
Identities = 38/146 (26%), Positives = 63/146 (43%), Gaps = 14/146 (10%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLN-- 1072
+ + DI +++ IVNAAN L GGGV GA+++ A+ E +
Sbjct 3 GITLVQGDITRQS----ADAIVNAANSSLLGGGGVDGAIHRRGGPAILAECRRLRAGHLG 58
Query 1073 GPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQ-LLKAAYENF------NSQDILLA 1124
L G + + +L A+ +H VGP +A ED LL + Y +
Sbjct 59 KGLPTGRAVATTAGDLDARWVIHTVGPVWSATEDRSGLLASCYRESLRTADELGARTVAF 118
Query 1125 PLLSAGIFGAKPLQSLQVCVQTVRTQ 1150
P +S G++ + ++ V+TV T
Sbjct 119 PAISTGVYRWPMDDAARIAVETVATT 144
>sp|A2AKX3|SETX_MOUSE Probable helicase senataxin OS=Mus musculus
OX=10090 GN=Setx PE=1 SV=1
Length=2646
Score = 126 bits (317), Expect = 8e-27, Method: Composition-based stats.
Identities = 58/266 (22%), Positives = 96/266 (36%), Gaps = 46/266 (17%)
Query 5669 ADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCR 5728
V+ DE + + ++ R + +GDP QLP T+++ E Y S+
Sbjct 2151 FSCVIVDEAGQSCEVE-TLSPLIHRCNKLILVGDPKQLPP--TVISMKAQEYGYDQSMMA 2207
Query 5729 LMKTIG------------PDMFLGTCRRCPAEIVDTVSALVYDNKLKAHK-DKSAQC--- 5772
+ P + L R +I S VY+ LK ++ +S +C
Sbjct 2208 RFCKLLEENVEQNMIGRLPVLQLTIQYRMHPDICLFPSNYVYNKNLKTNRLTESIRCSSE 2267
Query 5773 -------FKMFYKGVITHDVSSAINRPQIGVVREFLT------RNPAWRKAVFISPYNSQ 5819
G D S IN +I +V E + ++ ++R I+ Y +Q
Sbjct 2268 WPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKEKRKDISFRNIGIITHYKAQ 2327
Query 5820 NAVASKILG--------LPTQTVDSSQGSEYDYVIFT------QTTETAHSCNVNRFNVA 5865
+ K L TVD+ QG + D +I T ++ R NV
Sbjct 2328 KTMIQKDLEKEFDKKGPAEVDTVDAFQGRQKDCIIVTCVRASAVQGSIGFLASLQRLNVT 2387
Query 5866 ITRAKIGILCIMSDRDLYDKLQFTSL 5891
ITRAK + + R L + + L
Sbjct 2388 ITRAKYSLFILGHLRTLMENQHWYEL 2413
Score = 47.0 bits (110), Expect = 0.010, Method: Composition-based stats.
Identities = 20/69 (29%), Positives = 27/69 (39%), Gaps = 18/69 (26%)
Query 5577 KYSTLQGPPGTGKSHFAIGL------------------ALYYPSARIVYTACSHAAVDAL 5618
K + GPPGTGKS +GL R++ A S+AAVD L
Sbjct 1933 KICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENFNAKIKQNRVLVCAPSNAAVDEL 1992
Query 5619 CEKALKYLP 5627
+K +
Sbjct 1993 MKKIILEFK 2001
>sp|Q97AU0|Y719_THEVO Uncharacterized protein TV0719 OS=Thermoplasma
volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 /
NBRC 15438 / GSS1) OX=273116 GN=TV0719 PE=4 SV=1
Length=186
Score = 113 bits (282), Expect = 2e-26, Method: Composition-based stats.
Identities = 39/144 (27%), Positives = 60/144 (42%), Gaps = 14/144 (10%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP- 1074
+ I DI N IVNAAN L GGGV GA++ + E + + P
Sbjct 11 IEIIEGDIT----DVNCEAIVNAANPSLMGGGGVDGAIHLKGGKTIDLECAELRRTKWPK 66
Query 1075 -LTVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQ--LLKAAYENF-----NSQDILLAP 1125
L G + + SG L AK +H VGP E+ L + Y + + + P
Sbjct 67 GLPPGEADITSGGKLKAKYVIHTVGPIYRGQEEDAETLYSSYYRSLEIAKIHGIKCIAFP 126
Query 1126 LLSAGIFGAKPLQSLQVCVQTVRT 1149
+S GI+G ++ + ++ V
Sbjct 127 AISTGIYGYPFEEASVIALKAVTD 150
>sp|Q7Z333|SETX_HUMAN Probable helicase senataxin OS=Homo sapiens
OX=9606 GN=SETX PE=1 SV=4
Length=2677
Score = 125 bits (313), Expect = 2e-26, Method: Composition-based stats.
Identities = 62/292 (21%), Positives = 100/292 (34%), Gaps = 54/292 (18%)
Query 5669 ADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCR 5728
V+ DE + + ++ R + +GDP QLP T+++ E Y S+
Sbjct 2175 FSCVIVDEAGQSCEIE-TLTPLIHRCNKLILVGDPKQLPP--TVISMKAQEYGYDQSMMA 2231
Query 5729 LMKTIG------------PDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSA-QC--- 5772
+ P + L R +I S VY+ LK ++ A +C
Sbjct 2232 RFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYVYNRNLKTNRQTEAIRCSSD 2291
Query 5773 -------FKMFYKGVITHDVSSAINRPQIGVVREFLT------RNPAWRKAVFISPYNSQ 5819
G D S IN +I +V E + ++ ++R I+ Y +Q
Sbjct 2292 WPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDVSFRNIGIITHYKAQ 2351
Query 5820 NAVASKILG--------LPTQTVDSSQGSEYDYVIF------TQTTETAHSCNVNRFNVA 5865
+ K L TVD+ QG + D VI + ++ R NV
Sbjct 2352 KTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSIQGSIGFLASLQRLNVT 2411
Query 5866 ITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKII 5917
ITRAK + + R L + N A+ + K C K
Sbjct 2412 ITRAKYSLFILGHLRTLMEN--------QHWNQLIQDAQKRGAIIKTCDKNY 2455
Score = 47.0 bits (110), Expect = 0.010, Method: Composition-based stats.
Identities = 20/69 (29%), Positives = 27/69 (39%), Gaps = 18/69 (26%)
Query 5577 KYSTLQGPPGTGKSHFAIGL------------------ALYYPSARIVYTACSHAAVDAL 5618
K + GPPGTGKS +GL R++ A S+AAVD L
Sbjct 1957 KICLIHGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDEL 2016
Query 5619 CEKALKYLP 5627
+K +
Sbjct 2017 MKKIILEFK 2025
>sp|O94247|HCS1_SCHPO DNA polymerase alpha-associated DNA helicase
A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
OX=284812 GN=hcs1 PE=3 SV=1
Length=660
Score = 122 bits (306), Expect = 4e-26, Method: Composition-based stats.
Identities = 84/425 (20%), Positives = 136/425 (32%), Gaps = 116/425 (27%)
Query 5573 VGMQKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVD-------------- 5616
+ +++ S + GPPGTGK+H I L + RI+ S+ AVD
Sbjct 222 IAVKELSLIHGPPGTGKTHTLVEIIQQLVLRNKRILVCGASNLAVDNIVDRLSSSGIPMV 281
Query 5617 ----------ALCEKALKYLP---------------IDKC-SRIIPARARVECFDKFKVN 5650
++ + +L L ID C S+I + E + +K
Sbjct 282 RLGHPARLLPSILDHSLDVLSRTGDNGDVIRGISEDIDVCLSKITKTKNGRERREIYKNI 341
Query 5651 S------------------TLEQYVFCTVNA-----LPETTADIVVFDEISMATNYDLSV 5687
+ + VFCT++ L D V+ DE S A +
Sbjct 342 RELRKDYRKYEAKTVANIVSASKVVFCTLHGAGSRQLKGQRFDAVIIDEASQALEPQCWI 401
Query 5688 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGP--DMFLGTCRRC 5745
L + GD QL + Y + RL+K+ G FL R
Sbjct 402 PL--LGMNKVILAGDHMQLSPNVQS------KRPYISMFERLVKSQGDLVKCFLNIQYRM 453
Query 5746 PAEIVDTVSALVYDNKLKAHKDKSAQCF--------------KMFYK---GVITHDVSS- 5787
I S YD+KL ++ + +++ G D S
Sbjct 454 HELISKFPSDTFYDSKLVPAEEVKKRLLMDLENVEETELTDSPIYFYDTLGNYQEDDRSE 513
Query 5788 -------------AINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKIL-----GL 5829
+ + L + ++PYN+Q A+ ++L +
Sbjct 514 DMQNFYQDSKSNHWEAQIVSYHISGLLEAGLEAKDIAVVTPYNAQVALIRQLLKEKGIEV 573
Query 5830 PTQTVDSSQGSEYDYVIFTQTT-----ETAHSCNVNRFNVAITRAKIGILCIMSDRDLYD 5884
+VD QG E + +IF+ E R NVAITR K + I +
Sbjct 574 EMGSVDKVQGREKEAIIFSLVRSNDVREVGFLAEKRRLNVAITRPKRHLCVIGDSNTVKW 633
Query 5885 KLQFT 5889
+F
Sbjct 634 ASEFF 638
>sp|Q6PAV8|MACD2_XENLA ADP-ribose glycohydrolase MACROD2 OS=Xenopus
laevis OX=8355 GN=macrod2 PE=2 SV=1
Length=418
Score = 118 bits (296), Expect = 5e-26, Method: Composition-based stats.
Identities = 46/210 (22%), Positives = 79/210 (38%), Gaps = 21/210 (10%)
Query 981 WLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAAN 1040
LD E + +E + L + V+ DI + IVNAAN
Sbjct 35 SLDKIPSLMEELKSKASSDDESPEEIQVKNSLCEKVSFYKGDITQLE----VDAIVNAAN 90
Query 1041 IHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGPN 1099
L GGGV G +++A+ ++ E + G G + + G+ L AK +H VGP
Sbjct 91 TSLLGGGGVDGCIHRASGPSLLAECREL----GGCETGQAKITCGYELPAKYVIHTVGPI 146
Query 1100 LNAG---EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQ 1150
Q L + Y + N + P +S GI+G + V + TV+
Sbjct 147 ARGHITPNHKQDLASCYNSSLTLATENDIRTIAFPCISTGIYGYPNEPAANVALTTVKE- 205
Query 1151 VYIAVNDKALYEQVVMDYLDNLKPRVEAPK 1180
++ ++V+ + ++ K
Sbjct 206 --FLKKNRDKIDRVIFCVFLEVDFKIYKRK 233
>sp|Q9EYI6|Y189_STRNO Macro domain-containing protein in sno 5'region
OS=Streptomyces nogalater OX=38314 PE=4 SV=1
Length=181
Score = 112 bits (279), Expect = 5e-26, Method: Composition-based stats.
Identities = 41/163 (25%), Positives = 69/163 (42%), Gaps = 20/163 (12%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI-KLNGP 1074
+ + DI ++ + +VNAAN L GGGV GA+++ A+ E G
Sbjct 4 ITLVQGDITRQ----HADALVNAANSSLLGGGGVDGAIHRRGGPAILAECRALRASRYGE 59
Query 1075 -LTVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQ-LLKAAYENF------NSQDILLAP 1125
L G + + +L A+ +H VGP ++ ED LL + Y + P
Sbjct 60 GLPTGRAVATTAGDLDARWVIHTVGPVWSSTEDRSDLLASCYRESLRLAGELGARTVAFP 119
Query 1126 LLSAGIFGAKPLQSLQVCVQTVR------TQVYIAVNDKALYE 1162
LS G++ + ++ V+TVR +V + D Y+
Sbjct 120 ALSTGVYRWPMGDAARIAVETVRTTPTAVEEVRFVLFDTHAYD 162
>sp|Q9RS39|Y2288_DEIRA Macro domain-containing protein DR_2288
OS=Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 /
JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279
/ VKM B-1422 / R1) OX=243230 GN=DR_2288 PE=4 SV=1
Length=170
Score = 111 bits (277), Expect = 5e-26, Method: Composition-based stats.
Identities = 33/146 (23%), Positives = 60/146 (41%), Gaps = 20/146 (14%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPL 1075
+ + DI + +V AAN L GGGV G +++A + + I+ G
Sbjct 3 LELVQGDIAHQ----PVDAVVTAANKQLMGGGGVDGVIHRAAGPRLLQA----IRPIGGT 54
Query 1076 TVGGSCLLSGHNL----AKKCLHVVGPNLNAGE--DIQLLKAAYENF------NSQDILL 1123
G + + +L K +H VGP G+ + +LL AY N +
Sbjct 55 PTGTAVITPAFDLERQGVKYVIHAVGPIWRGGQHGEAELLAGAYRESLRLGVENGCRSVA 114
Query 1124 APLLSAGIFGAKPLQSLQVCVQTVRT 1149
P +S G++G ++ + + T++
Sbjct 115 FPSISTGVYGYPLDRAAPIALATIQD 140
>sp|Q57568|Y104_METJA Uncharacterized ATP-dependent helicase MJ0104
OS=Methanocaldococcus jannaschii (strain ATCC 43067 /
DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) OX=243232 GN=MJ0104
PE=3 SV=1
Length=663
Score = 121 bits (303), Expect = 8e-26, Method: Composition-based stats.
Identities = 53/247 (21%), Positives = 98/247 (40%), Gaps = 38/247 (15%)
Query 5669 ADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCR 5728
D++V DE S A + ++ + + GD QLP P L L+ F + +
Sbjct 395 FDVIVIDEGSQAMEPSCLIPI--VKGRKLIMAGDHKQLP-PTVLSENEELKKTLFERLIK 451
Query 5729 LMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKA-------------HKDKSAQCFKM 5775
L R +I++ + + Y+NKLKA +++ + +
Sbjct 452 KYPEFSS--ILEIQYRMNEKIMEFPNKMFYNNKLKADESVKNITLLDLVKEEEIDEVDRD 509
Query 5776 F----------YKGVITHD--VSSAINRPQIGVVREFLTRNPAWRKAV-FISPYNSQNAV 5822
+G+ D S N + V E + + ++ I+PY++Q
Sbjct 510 IINEIPVQFINVEGIERKDKESPSYYNIEEAEKVLEIVKKLVKYKIPTNVITPYDAQVRY 569
Query 5823 ASKI-----LGLPTQTVDSSQGSEYDYVI--FTQTTETAHSCNVNRFNVAITRAKIGILC 5875
++ + + TVD QG E + ++ F +T ++ R NVAITRAK ++
Sbjct 570 LRRLFEEHNIDIEVNTVDGFQGRENEAIVISFVRTKNFGFLKDLRRLNVAITRAKRKLIL 629
Query 5876 IMSDRDL 5882
I ++ L
Sbjct 630 IGNENLL 636
Score = 45.8 bits (107), Expect = 0.018, Method: Composition-based stats.
Identities = 22/83 (27%), Positives = 39/83 (47%), Gaps = 9/83 (11%)
Query 5561 DEFSSNVANYQKVGMQKYST------LQGPPGTGKS---HFAIGLALYYPSARIVYTACS 5611
+ + N+ QK+ ++K + GPPGTGK+ I + + +++ TA S
Sbjct 179 EFYDKNLNESQKLAVKKAVLSRDLYLIHGPPGTGKTRTITEVIVQEVKFNKHKVLATADS 238
Query 5612 HAAVDALCEKALKYLPIDKCSRI 5634
+ A D + E +K P K R+
Sbjct 239 NIAADNILEYLIKKYPDLKVVRV 261
>sp|Q99MV5|M10L1_MOUSE RNA helicase Mov10l1 OS=Mus musculus OX=10090
GN=Mov10l1 PE=1 SV=1
Length=1187
Score = 121 bits (303), Expect = 2e-25, Method: Composition-based stats.
Identities = 67/382 (18%), Positives = 123/382 (32%), Gaps = 88/382 (23%)
Query 5583 GPPGTGKS----HFAIGLALYYPSARIVYTACSHAAVDALCEKALKYL--------PIDK 5630
GPPGTGK+ + + P +RI+ A S++A D +C + + ++
Sbjct 772 GPPGTGKTVTIIEAVLQVHYALPDSRILVCAPSNSAADLVCLRLHESKVPKPAAMVRVNA 831
Query 5631 CSRI---IPARARVECFDK---FKVNSTLEQYVFCTVNAL------PETTADIVVFDEIS 5678
R I + C D ++ + C+ L V DE
Sbjct 832 TCRFEETIIDAIKPYCRDGEDIWRASRFRIIITTCSSAGLFYQIGVRVGYFTHVFVDEAG 891
Query 5679 MATNYDLSVVNARLRA--KHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK----- 5731
A+ + + + V GDP QL + ++ + S+ +
Sbjct 892 QASEPECLIPLGLISDINGQIVLAGDPMQLGP--VIKSRLAMAYGLNVSMLERLMSRPAY 949
Query 5732 -----------TIGPDMF--LGTCRRCPAEIVDTVSALVYDNKLKAHKDKSA-------- 5770
P + L R + ++ S L Y +L+ D
Sbjct 950 LRDENAFGACGAYNPLLVTKLVKNYRSHSALLALPSRLFYHRELEVCADPKVVTSLLGWE 1009
Query 5771 ----QCFKMFYKGVITHDVS-----SAINRPQIGVVREF-------LTRNPAWRKAVFIS 5814
+ F + + GV ++ S + + V + ++ + + I+
Sbjct 1010 KLPRKGFPLIFHGVRGNEAREGRSPSWFSPAEAVQVMRYCCLLARSVSSQVSSKDIGVIT 1069
Query 5815 PYNSQNAVASKIL------GLPTQTVDSSQGSEYDYVIFTQTTET-----------AHSC 5857
PY Q +L + +V+ QG EY ++ +
Sbjct 1070 PYRKQVEKIKILLRNVDLTDIKVGSVEEFQGQEYLVIVISTVRSNEDRFEDDRYFLGFLS 1129
Query 5858 NVNRFNVAITRAKIGILCIMSD 5879
N RFNVAITR K +L I+ +
Sbjct 1130 NSKRFNVAITRPK-ALLIILGN 1150
>sp|Q44020|YGB2_CUPNE Macro domain-containing protein in gbd 3'region
OS=Cupriavidus necator OX=106590 PE=4 SV=1
Length=173
Score = 109 bits (273), Expect = 2e-25, Method: Composition-based stats.
Identities = 45/173 (26%), Positives = 73/173 (42%), Gaps = 17/173 (10%)
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNG 1073
+++ + DI + IVNAAN L GGGV GA++ A A+++ G
Sbjct 4 EHLQVVHGDITRME----VDAIVNAANSGLLGGGGVDGAIHGAGGSAIKEACRAIRDTQG 59
Query 1074 PLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENF------NSQDILLA 1124
G + + +G +L A +H VGP G+ + +LL AY N + L
Sbjct 60 GCPTGEAVITTGGHLPAPYVIHAVGPVWQGGDQGEDELLANAYRNSIRLAAQHHLRRLAF 119
Query 1125 PLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVE 1177
P +S GI+ ++ + + VR + A EQV D+ R+
Sbjct 120 PNISTGIYAFPRERAADIAIAAVREALAAA----PEIEQVTFVCFDDENYRLY 168
>sp|Q3UYG8|MACD2_MOUSE ADP-ribose glycohydrolase MACROD2 OS=Mus
musculus OX=10090 GN=Macrod2 PE=1 SV=1
Length=475
Score = 117 bits (293), Expect = 2e-25, Method: Composition-based stats.
Identities = 50/274 (18%), Positives = 101/274 (37%), Gaps = 30/274 (11%)
Query 954 EDDYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLT 1013
E+ + L + + + L E+ + + + + + Q L+
Sbjct 13 EEKERLLKMTLEERRKEYIRDYVSLSTILSW-KEEMKSKGQNDEENTQEAPQM--KKSLS 69
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNG 1073
+ V++ DI IVNAAN L GGGV G +++A + E + LNG
Sbjct 70 EKVSLYRGDIT----LLEVDAIVNAANASLLGGGGVDGCIHRAAGPCLLAECRN---LNG 122
Query 1074 PLTVGGSCLLSGHNL-AKKCLHVVGPNLNA---GEDIQLLKAAYENF------NSQDILL 1123
G + + G++L AK +H VGP G + L Y++ N+ +
Sbjct 123 -CETGHAKITCGYDLPAKYVIHTVGPIARGHINGSHKEDLANCYQSSLKLVKENNLRSVA 181
Query 1124 APLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEE 1183
P +S GI+G + + + T++ + ++++ + ++ K E
Sbjct 182 FPCISTGIYGFPNEPAAVIALGTIKE---WLAKNHQEVDRIIFCVFLEVDFKIYKKKMNE 238
Query 1184 PPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTT 1217
+D+ D+K + + +
Sbjct 239 FFPVDDNNEGT------DADMKEDSEGPEPKGLS 266
>sp|Q0VGT4|ZGRF1_MOUSE 5'-3' DNA helicase ZGRF1 OS=Mus musculus
OX=10090 GN=Zgrf1 PE=1 SV=2
Length=1863
Score = 119 bits (297), Expect = 1e-24, Method: Composition-based stats.
Identities = 52/248 (21%), Positives = 89/248 (36%), Gaps = 29/248 (12%)
Query 5659 CTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL 5718
C L + +VV DE S T + AR + + + +GDP QLP P +
Sbjct 1554 CAFPCLNDLKFPVVVLDECSQMTEPASLLPIARFQCEKLILVGDPKQLP-PTIQGSDAAH 1612
Query 5719 EPEYFNSVCRLMKTIGPD-MFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ------ 5771
E ++ + +G + L T RC I + L Y+ L + +
Sbjct 1613 ENGLEQTLFDRLCLMGHKPVLLRTQYRCHPAISAIANDLFYEGSLVNGISERERSPVLEW 1672
Query 5772 ----CFKMFYKGVITHDVSSAINRPQIGV----VREFLTRNPAWRKAVFISPYNSQNAVA 5823
CF +S +N + ++ + I+ Y SQ
Sbjct 1673 LPTLCFYNVTGAEQVERENSFVNVAEATFTLKLIQSLMASGVESCMIGVITLYKSQMYKI 1732
Query 5824 SKILG-----------LPTQTVDSSQGSEYDYVIFT--QTTETAHSCNVNRFNVAITRAK 5870
+L + TVD+ QG+E + I + +T + + R NVA+TR +
Sbjct 1733 CNLLSAVDVGHPDVKAVQVSTVDAFQGAEKEITILSCVRTRQVGFIDSEKRMNVALTRGR 1792
Query 5871 IGILCIMS 5878
+L + S
Sbjct 1793 RHLLIVGS 1800
>sp|A1Z1Q3|MACD2_HUMAN ADP-ribose glycohydrolase MACROD2 OS=Homo
sapiens OX=9606 GN=MACROD2 PE=1 SV=2
Length=425
Score = 113 bits (283), Expect = 2e-24, Method: Composition-based stats.
Identities = 45/192 (23%), Positives = 80/192 (42%), Gaps = 22/192 (11%)
Query 1000 EEPVNQFTGYLK-LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATN 1058
EE + + K LT+ V++ DI IVNAAN L GGGV G +++A
Sbjct 55 EENTQETSQVKKSLTEKVSLYRGDIT----LLEVDAIVNAANASLLGGGGVDGCIHRAAG 110
Query 1059 GAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNA---GEDIQLLKAAYE 1114
+ E + LNG G + + G++L AK +H VGP G + L Y+
Sbjct 111 PCLLAECRN---LNG-CDTGHAKITCGYDLPAKYVIHTVGPIARGHINGSHKEDLANCYK 166
Query 1115 NF------NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDY 1168
+ N+ + P +S GI+G + + + T++ + ++++
Sbjct 167 SSLKLVKENNIRSVAFPCISTGIYGFPNEPAAVIALNTIKE---WLAKNHHEVDRIIFCV 223
Query 1169 LDNLKPRVEAPK 1180
+ ++ K
Sbjct 224 FLEVDFKIYKKK 235
>sp|P34243|HCS1_YEAST DNA polymerase alpha-associated DNA helicase
A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=HCS1 PE=1 SV=1
Length=683
Score = 115 bits (289), Expect = 4e-24, Method: Composition-based stats.
Identities = 52/264 (20%), Positives = 89/264 (34%), Gaps = 51/264 (19%)
Query 5665 PETTADIVVFDEISMATNYD--LSVVNARLRAKHYVYIGDPAQLPA----PRTLLTKGTL 5718
D ++ DE+S A + ++ + + V GD QLP L
Sbjct 385 NFQLFDTLIIDEVSQAMEPQCWIPLIAHQNQFHKLVLAGDNKQLPPTIKTEDDKNVIHNL 444
Query 5719 EPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK--------------- 5763
E F+ + ++ FL R +I++ S +Y+ KL
Sbjct 445 ETTLFDRIIKIFPKRDMVKFLNVQYRMNQKIMEFPSHSMYNGKLLADATVANRLLIDLPT 504
Query 5764 ----AHKDKSAQCFKMFYK---GVITHDV-------SSAINRPQIGVVREFLTR----NP 5805
+D + + G + S N +I +V+E + N
Sbjct 505 VDATPSEDDDDTKIPLIWYDTQGDEFQETADEATILGSKYNEGEIAIVKEHIENLRSFNV 564
Query 5806 AWRKAVFISPYNSQNAVASKIL-------GLPTQTVDSSQGSEYDYVIFTQTT-----ET 5853
ISPYN+Q + K++ + TVD QG E D +I + E
Sbjct 565 PENSIGVISPYNAQVSHLKKLIHDELKLTDIEISTVDGFQGREKDVIILSLVRSNEKFEV 624
Query 5854 AHSCNVNRFNVAITRAKIGILCIM 5877
R NVA+TR + ++ +
Sbjct 625 GFLKEERRLNVAMTRPRRQLVVVG 648
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 27/101 (27%), Positives = 42/101 (42%), Gaps = 10/101 (10%)
Query 5539 PTLVPQEHYVRITG-LYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS----HFA 5593
P + + I L P LN S + + N A + + GPPGTGK+
Sbjct 189 PFIPNTNSFQNIKSFLNPNLNDSQKTAINFAI-----NNDLTIIHGPPGTGKTFTLIELI 243
Query 5594 IGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRI 5634
L + P RI+ S+ +VD + E+ +P + RI
Sbjct 244 QQLLIKNPEERILICGPSNISVDTILERLTPLVPNNLLLRI 284
>sp|Q9HJ67|Y1105_THEAC Uncharacterized protein Ta1105 OS=Thermoplasma
acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062
/ NBRC 15155 / AMRC-C165) OX=273075 GN=Ta1105 PE=4 SV=2
Length=196
Score = 106 bits (265), Expect = 5e-24, Method: Composition-based stats.
Identities = 37/143 (26%), Positives = 63/143 (44%), Gaps = 15/143 (10%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP- 1074
+A++ DI + + IVNAAN L GGGV GA++ A + E + P
Sbjct 11 LAVEVGDITES----DAEAIVNAANSSLMGGGGVDGAIHSAAGPELNGELVKIRRERYPN 66
Query 1075 -LTVGGSCLLSGHNL-AKKCLHVVGPNLNAGE--DIQLLKAAYENFNSQ------DILLA 1124
L G + + G+ L A +H VGP G + +L +Y + +
Sbjct 67 GLPPGEAVITRGYRLKASHIIHTVGPVWMGGRNGEDDVLYRSYRSCLDLAREFGIHDIAF 126
Query 1125 PLLSAGIFGAKPLQSLQVCVQTV 1147
P LS G +G ++ ++ +++V
Sbjct 127 PALSTGAYGFPFDRAERIAIRSV 149
>sp|Q9BQ69|MACD1_HUMAN ADP-ribose glycohydrolase MACROD1 OS=Homo
sapiens OX=9606 GN=MACROD1 PE=1 SV=2
Length=325
Score = 109 bits (272), Expect = 1e-23, Method: Composition-based stats.
Identities = 40/170 (24%), Positives = 68/170 (40%), Gaps = 20/170 (12%)
Query 990 EIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGV 1049
E+ EEP + +L + +++ DI K IVNAAN L GGGV
Sbjct 130 EMAKGVAVKVEEPRYKKD--KQLNEKISLLRSDITKLE----VDAIVNAANSSLLGGGGV 183
Query 1050 AGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGPNL----NAGE 1104
G +++A + E G + + G+ L AK +H VGP +A +
Sbjct 184 DGCIHRAAGPLLTDECRTL----QSCKTGKAKITGGYRLPAKYVIHTVGPIAYGEPSASQ 239
Query 1105 DIQLLKAAYENF-----NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
+L + + + P +S G+FG + ++ + T+R
Sbjct 240 AAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPCEAAAEIVLATLRE 289
>sp|Q2KHU5|MACD1_BOVIN ADP-ribose glycohydrolase MACROD1 OS=Bos
taurus OX=9913 GN=MACROD1 PE=2 SV=1
Length=325
Score = 108 bits (271), Expect = 2e-23, Method: Composition-based stats.
Identities = 43/210 (20%), Positives = 76/210 (36%), Gaps = 26/210 (12%)
Query 990 EIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGV 1049
E EEP ++ +L + +++ DI K IVNAAN L GGGV
Sbjct 130 ETAKGVTVKVEEP--KYKKDKQLNEKISLFRGDITKLE----VDAIVNAANSSLLGGGGV 183
Query 1050 AGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNA----GE 1104
G +++A + E G + + G+ L AK +H VGP + +
Sbjct 184 DGCIHRAAGPLLTDECRTL----QNCETGKAKITCGYRLPAKYVIHTVGPIAHGEPSASQ 239
Query 1105 DIQLLKAAYENF-----NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKA 1159
+L + + P +S G+FG + +V + +R K
Sbjct 240 AAELRSCYLSSLDLLLEHRLRSAAFPCISTGVFGYPNEAAAEVVLTALRE---WLEQHKD 296
Query 1160 LYEQVVMDYLDNLKPRVEAPKQEEPPNTED 1189
+++++ E +E P+
Sbjct 297 KVDRLIICVFLEKD---ENIYRERLPHYFP 323
>sp|Q8K4G6|MACD1_RAT ADP-ribose glycohydrolase MACROD1 (Fragment)
OS=Rattus norvegicus OX=10116 GN=Macrod1 PE=2 SV=2
Length=258
Score = 107 bits (266), Expect = 2e-23, Method: Composition-based stats.
Identities = 41/190 (22%), Positives = 73/190 (38%), Gaps = 24/190 (13%)
Query 1010 LKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYI 1069
+L + +++ DI K IVNAAN L GGGV G +++A + E
Sbjct 81 KQLNEKISLFRGDITKLE----VDAIVNAANNSLLGGGGVDGCIHRAAGSLLTDECRTL- 135
Query 1070 KLNGPLTVGGSCLLSGHNL-AKKCLHVVGPNL----NAGEDIQLLKAAYENF-----NSQ 1119
G + + G+ L AK +H VGP A + +L + +
Sbjct 136 ---QNCETGKAKITCGYRLPAKHVIHTVGPIAVGQPTASQAAELRSCYLSSLDLLLEHRL 192
Query 1120 DILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAP 1179
+ P +S G+FG ++ +V + T+R K +++++ +
Sbjct 193 RSVAFPCISTGVFGYPNEEAAEVVLATLRE---WLEQHKDKVDRLIICVFLEKDEGIY-- 247
Query 1180 KQEEPPNTED 1189
QE P+
Sbjct 248 -QERLPHYFP 256
>sp|Q86YA3|ZGRF1_HUMAN 5'-3' DNA helicase ZGRF1 OS=Homo sapiens
OX=9606 GN=ZGRF1 PE=1 SV=3
Length=2104
Score = 114 bits (284), Expect = 5e-23, Method: Composition-based stats.
Identities = 52/248 (21%), Positives = 92/248 (37%), Gaps = 31/248 (13%)
Query 5659 CTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL 5718
C + + +VV DE S T + AR + + +GDP QLP P +
Sbjct 1793 CPFPCMNDLKFPVVVLDECSQITEPASLLPIARFECEKLILVGDPKQLP-PTIQGSDAAH 1851
Query 5719 EPEYFNSVCRLMKTIGPD-MFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ------ 5771
E ++ + +G + L T RC I + L Y L + +
Sbjct 1852 ENGLEQTLFDRLCLMGHKPILLRTQYRCHPAISAIANDLFYKGALMNGVTEIERSPLLEW 1911
Query 5772 ----CFKMFYKGVITHDVSSAINRP-----QIGVVREFLTRNPAWRKAVFISPYNSQNAV 5822
CF KG+ + ++ + + +++ + A I+ Y SQ
Sbjct 1912 LPTLCFYN-VKGLEQIERDNSFHNVAEATFTLKLIQSLIASGIAGSMIGVITLYKSQMYK 1970
Query 5823 ASKIL-----------GLPTQTVDSSQGSEYDYVIFT--QTTETAHSCNVNRFNVAITRA 5869
+L + TVD+ QG+E + +I + +T + + R NVA+TR
Sbjct 1971 LCHLLSAVDFHHPDIKTVQVSTVDAFQGAEKEIIILSCVRTRQVGFIDSEKRMNVALTRG 2030
Query 5870 KIGILCIM 5877
K +L +
Sbjct 2031 KRHLLIVG 2038
>sp|Q922B1|MACD1_MOUSE ADP-ribose glycohydrolase MACROD1 OS=Mus
musculus OX=10090 GN=Macrod1 PE=1 SV=2
Length=323
Score = 106 bits (264), Expect = 1e-22, Method: Composition-based stats.
Identities = 39/170 (23%), Positives = 68/170 (40%), Gaps = 20/170 (12%)
Query 990 EIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGV 1049
E E+P ++ +L + +++ DI K IVNAAN L GGGV
Sbjct 128 ETAKGLAVKVEDP--KYKKDKQLNEKISLYRGDITKLE----VDAIVNAANSSLLGGGGV 181
Query 1050 AGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGPNL----NAGE 1104
G +++A + E G + + G+ L AK +H VGP A +
Sbjct 182 DGCIHRAAGSLLTDECRTL----QNCETGKAKITCGYRLPAKYVIHTVGPIAVGQPTASQ 237
Query 1105 DIQLLKAAYENF-----NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
+L + + + P +S G+FG ++ +V + ++R
Sbjct 238 AAELRSCYLSSLDLLLEHRLRSVAFPCISTGVFGYPNEEAAEVVLASLRE 287
>sp|P38935|SMBP2_HUMAN DNA-binding protein SMUBP-2 OS=Homo sapiens
OX=9606 GN=IGHMBP2 PE=1 SV=3
Length=993
Score = 108 bits (270), Expect = 2e-21, Method: Composition-based stats.
Identities = 61/257 (24%), Positives = 93/257 (36%), Gaps = 41/257 (16%)
Query 5664 LPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYF 5723
LPE+ D+VV DE + A + S L+A+ + GD QLP P T+ K L
Sbjct 364 LPESYFDVVVIDECAQA--LEASCWIPLLKARKCILAGDHKQLP-PTTVSHKAALAGLSL 420
Query 5724 NSVCRLMKTIGPD--MFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVI 5781
+ + RL + G L R I+ S +Y +L AH + +
Sbjct 421 SLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAA 480
Query 5782 THDVS--------SAINRPQIGVVREFLTRNP------------------AWRKAVFISP 5815
T + + ++ E NP R +SP
Sbjct 481 TEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSP 540
Query 5816 YNSQNAVASKIL-----GLPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVA 5865
YN Q + + L L ++VD QG E + VI + + E R NVA
Sbjct 541 YNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVA 600
Query 5866 ITRAKIGILCIMSDRDL 5882
+TRA+ + I R +
Sbjct 601 VTRARRHVAVICDSRTV 617
Score = 49.3 bits (116), Expect = 0.002, Method: Composition-based stats.
Identities = 16/49 (33%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Query 5576 QKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKA 5622
++ + + GPPGTGK+ I L +++ A S+ AVD L E+
Sbjct 207 KELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNIAVDNLVERL 255
>sp|Q9URU2|DNA2_SCHPO DNA replication ATP-dependent helicase/nuclease
dna2 OS=Schizosaccharomyces pombe (strain 972 / ATCC
24843) OX=284812 GN=dna2 PE=1 SV=2
Length=1397
Score = 108 bits (270), Expect = 2e-21, Method: Composition-based stats.
Identities = 88/426 (21%), Positives = 141/426 (33%), Gaps = 89/426 (21%)
Query 5576 QKYSTLQGPPGTGKSHFAIGL--ALYYPSARIVYTACSHAAVDALCEKA----LKYLPID 5629
+ YS + G PGTGK+ L +L +I+ T+ +H AVD + K + +
Sbjct 947 EHYSLILGMPGTGKTTTISSLIRSLLAKKKKILLTSFTHLAVDNILIKLKGCDSTIVRLG 1006
Query 5630 KCSRIIPARARVECFDKFKVNSTLE--------QYVFCT-----VNALPETTADIVVFDE 5676
+I P + + Q V C+ + + D + DE
Sbjct 1007 SPHKIHPLVKEFCLTEGTTFDDLASLKHFYEDPQIVACSSLGVYHSIFNKRKFDYCIIDE 1066
Query 5677 ISMATNYDLSVVNARLR-AKHYVYIGDPAQLPA--PRTLLTKGTLEPEYFNSVCRLMKTI 5733
S L + L+ A+ +V +GD QLP + +K L F +
Sbjct 1067 ASQIP---LPICLGPLQLAEKFVLVGDHYQLPPLVKNSRTSKDGLSLSLFKLLSEKHPEA 1123
Query 5734 GPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQ---CFKMFYKGVITHDVSSA-- 5788
L R +I S L+Y L +Q + D SS+
Sbjct 1124 V--TTLRLQYRMNEDINSLSSELIYGGNLVCGSKTISQKKLILPKAHLSDGLPDSSSSLH 1181
Query 5789 --------------INRPQI---------------------GVVREFLTRNPAWRKAVFI 5813
N I V FL R I
Sbjct 1182 WVNKLINPSHSVIFFNTDDILGVESKTNNILENHTEAFLIEQAVSSFLERGVKQSSIGII 1241
Query 5814 SPYNSQNAVASKIL----GLPTQTVDSSQGSEYDYVIFTQTTETAHSC------NVNRFN 5863
S Y SQ + SK L + TVD QG + D ++ + + + + +R N
Sbjct 1242 SIYKSQVELLSKNLKSFTEIEINTVDRYQGRDKDIILISFVRSNSKNLVGELLRDWHRLN 1301
Query 5864 VAITRAKIGILCIMSDRDLYDK------LQFTS-----LEIPRRNVATLQAENVTGLFKD 5912
VA++RAK+ + S L L+ + ++AT EN + + KD
Sbjct 1302 VALSRAKVKCIMFGSLSTLSSSNIVSHLLKLLEKNKWIFTLNENDIATKFDENSSPI-KD 1360
Query 5913 CSKIIT 5918
CS++ T
Sbjct 1361 CSQVAT 1366
>sp|P32644|ECM32_YEAST Putative ATP-dependent RNA helicase ECM32
OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=ECM32 PE=1 SV=1
Length=1121
Score = 106 bits (265), Expect = 6e-21, Method: Composition-based stats.
Identities = 75/444 (17%), Positives = 143/444 (32%), Gaps = 139/444 (31%)
Query 5571 QKVGMQKYSTLQGPPGTGKSHFAIGLALY----YPSARIVYTACSHAAVDALCEKALK-- 5624
+ V + LQGPPGTGK+ + + + + I+ A S+ A+D + EK ++
Sbjct 658 EHVLNNSITILQGPPGTGKTSTIEEIIIQVIERFHAFPILCVAASNIAIDNIAEKIMENR 717
Query 5625 --------------------------------YLPIDKCSRIIPARAR----------VE 5642
Y + +++ + R +
Sbjct 718 PQIKILRILSKKKEQQYSDDHPLGEICLHNIVYKNLSPDMQVVANKTRRGEMISKSEDTK 777
Query 5643 CFDKF-----KVNSTLEQYVFCTVNALPE-----TTADIVVFDEISMATNYDLSVVNARL 5692
+ + KV S + + A +V+ DE + ++ V +
Sbjct 778 FYKEKNRVTNKVVSQSQIIFTTNIAAGGRELKVIKECPVVIMDEATQSSEASTLVPLSLP 837
Query 5693 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK---TIGPDMFLGTCRRCPAEI 5749
+++V++GD QL + + P+ S+ + T + L T R +I
Sbjct 838 GIRNFVFVGDEKQLSSFSNI-------PQLETSLFERVLSNGTYKNPLMLDTQYRMHPKI 890
Query 5750 VDTVSALVYDNKLKAHKDKSAQCFK------MFYKGVITHDVSSAINRPQI--------- 5794
+ +Y+ +LK + + FY+ + + + I
Sbjct 891 SEFPIKKIYNGELKDGVTDEQKAWPGVQHPLFFYQCDLGPESRVRSTQRDIVGFTYENKH 950
Query 5795 ---GVVR----EFLTRNPAWRKAVFISPYNSQNAVASKIL-------------------- 5827
+V+ L + + I+PY++Q + S IL
Sbjct 951 ECVEIVKIIQILMLDKKVPLEEIGVITPYSAQRDLLSDILTKNVVINPKQISMQQEYDEI 1010
Query 5828 ------------------------GLPTQTVDSSQGSEYDYVIFTQTTE-----TAHSCN 5858
GL TVDS QG E ++IF+ +
Sbjct 1011 ELFNAAGSQGTAGSLQNNVINIINGLHVATVDSFQGHEKSFIIFSCVRNNTENKIGFLRD 1070
Query 5859 VNRFNVAITRAKIGILCIMSDRDL 5882
R NVA+TRAK G++ + + L
Sbjct 1071 KRRLNVALTRAKHGLIVVGNKNVL 1094
>sp|Q98TR3|RENT1_TAKRU Putative regulator of nonsense transcripts
1 OS=Takifugu rubripes OX=31033 GN=rent1 PE=3 SV=1
Length=1097
Score = 106 bits (264), Expect = 9e-21, Method: Composition-based stats.
Identities = 72/416 (17%), Positives = 131/416 (31%), Gaps = 98/416 (24%)
Query 5559 ISDEFSSNVANYQKVGMQKYSTLQGPPGTGKS----HFAIGLALYYPSARIVYTACSHAA 5614
+ D S V + V + S +QGPPGTGK+ L+ + ++ A S+ A
Sbjct 450 LPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLSR-QGNGPVLVCAPSNIA 508
Query 5615 VDAL--------------CEKALKYLPIDKCSRIIPARARV------------------- 5641
VD L C K+ + + + +
Sbjct 509 VDQLTEKIDKTGLKVVRLCAKSREAIESPVSFLALHNQISNMDSMPELQKLQQLKDETGE 568
Query 5642 ------ECFDKFK-------VNSTLEQYVFCTVNALPETT---ADIVVFDEISMATNYDL 5685
+ + K + + + C P ++ DE + AT
Sbjct 569 LSSADEKRYRALKRTAERELLMNADVIWCTCVRAGDPRLAKMQFRSILIDESTQATEPKC 628
Query 5686 SVVNARLRAKHYVYIGDPAQLPAP-RTLLTKGTLEPEYFNSVCRLMKTIG-PDMFLGTCR 5743
+ L AK + ++ A ++ K + S+ + +G + L
Sbjct 629 -IGPVELGAKQLIL----GEITASWSCVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQY 683
Query 5744 RCPAEIVDTVSALVYDNKLKAHKDKSAQC---------------FKMFYKGVITHDVS-- 5786
R + S + Y+ L+ + F +G S
Sbjct 684 RMHPALSAFPSNIFYEGSLQNGVTAGDRIKKGFDFQWPQPEKPMFFYVTQGQEEIASSGT 743
Query 5787 SAINRPQIGVVR----EFLTRNPAWRKAVFISPYNSQNAVAS-----------KILGLPT 5831
S +NR + V L + I+PY Q + K+ +
Sbjct 744 SYLNRTEAANVEKITTRLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQVEI 803
Query 5832 QTVDSSQGSEYDYVIFTQTTETAH-----SCNVNRFNVAITRAKIGILCIMSDRDL 5882
+VD+ QG E D++I + H + R NVA+TRAK G++ + + + L
Sbjct 804 ASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRAKYGVIIVGNPKAL 859
>sp|Q6J5K9|ARMI_DROME Probable RNA helicase armi OS=Drosophila
melanogaster OX=7227 GN=armi PE=1 SV=4
Length=1188
Score = 105 bits (262), Expect = 1e-20, Method: Composition-based stats.
Identities = 78/442 (18%), Positives = 130/442 (29%), Gaps = 124/442 (28%)
Query 5554 YPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAI----GLALYYPSARIVYTA 5609
NI + N+ L GPPG+GK+ I L P ARI+
Sbjct 704 RAVFNILRGEAENIPY----------VLFGPPGSGKTMTLIETLLQLVRNLPGARILVGT 753
Query 5610 CSHAAVDALCEKALKY-------------LPIDKCSRIIPARARVE----------CFDK 5646
S+++ D + ++ + + I P C DK
Sbjct 754 PSNSSADLVTKRLIDSKALLQGDFIRLVSYNQVEKDLIPPEIMSYCATSDVGAVGSCEDK 813
Query 5647 FKVNST------------LEQYVFCTVNAL--------PETTADIVVFDEISMATNYD-- 5684
V + + T L P V+FDE T +
Sbjct 814 MMVTESGLKLRCQAKFIGTHRITISTCTTLGNFLQLGFPAGHFTHVLFDEAGQCTEPETM 873
Query 5685 LSVVNARLRAKHYVYIGDPAQLPAPRT--LLTKGT---------LEPEYFNSVCRLMKTI 5733
+ +V + V GDP QL + T + +K LE + +
Sbjct 874 VPIVMLTKKRSQVVLSGDPRQLQSIVTSRIASKMGFSISFLERLLERSPYRKDLQRFPES 933
Query 5734 --GPDMFLGTC---RRCPAEIVDTVSALVYDNKLKAHKDKSA------------------ 5770
+ L R I+ S L YD++L +
Sbjct 934 SGYNPLVLTKLLYNYRALPSIMSIYSRLFYDDELIPVLSEKDSRESRLLSKLRCVFESEK 993
Query 5771 ---QCFKMFYKGVIT-----HDVSSAINRPQIGVV----REFLTRNPAWRKAVFISPYNS 5818
Q F+ G+I +D S N ++ V N + I+PY
Sbjct 994 DIPQAHGTFFYGIIGENRQNNDSPSWFNPQEVREVFLMTIALYRANVTADQIGIITPYQK 1053
Query 5819 QNAVASKI-LGLP-----TQTVDSSQGSEYDYVIFTQTTET------------AHSCNVN 5860
Q + + +G +V+ QG E D ++ + +
Sbjct 1054 QVKMLRSMFIGTDVVMPKIGSVEEFQGQERDIILISTVRSSEEILRMDARFSLGFVRCSK 1113
Query 5861 RFNVAITRAKIGILCIMSDRDL 5882
R NVA++RA+ ++ I + L
Sbjct 1114 RLNVAVSRAR-AMMIIFGNPHL 1134
>sp|P36328|POLN_EEVVP Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain P676) OX=36385 PE=1 SV=2
Length=2493
Score = 105 bits (263), Expect = 1e-20, Method: Composition-based stats.
Identities = 53/162 (33%), Positives = 69/162 (43%), Gaps = 30/162 (19%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ + DI +A VI+NAAN + GGGV GAL K ES D
Sbjct 1329 CAPSYHVVRGDIA----TATEGVIINAANSKGQPGGGVCGALYKKF-----PESFDL--- 1376
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQ---LLKAAYE------NFNSQDIL 1122
P+ VG + L+ G AK +H VGPN N +++ L AYE N N+ +
Sbjct 1377 -QPIEVGKARLVKG--AAKHIIHAVGPNFNKVSEVEGDKQLAEAYESIAKIVNDNNYKSV 1433
Query 1123 LAPLLSAGIFGA------KPLQSLQVCVQTVRTQVYIAVNDK 1158
PLLS GIF + L L + T V I DK
Sbjct 1434 AIPLLSTGIFSGNKDRLTQSLNHLLTALDTTDADVAIYCRDK 1475
Score = 51.2 bits (121), Expect = 5e-04, Method: Composition-based stats.
Identities = 57/297 (19%), Positives = 90/297 (30%), Gaps = 62/297 (21%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS G+ + + + + + C+ II
Sbjct 719 VYGVPGSGKS----GIIKSAVTKKDLVVSA----------------KKENCAEIIRD--- 755
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
V+ VN+ V + + + DE L + A +R K V
Sbjct 756 VKKMKGLDVNARTVDSVLLNG---CKHPVETLYIDEAFACHAGTLRALIAIIRPKKAVLC 812
Query 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
GDP Q + K E V RRC + VS L YD
Sbjct 813 GDPKQCGFFNMMCLKVHFNHEICTQVFHK----------SISRRCTKSVTSVVSTLFYDK 862
Query 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
+++ K I D + + Q ++ LT W K + I Y
Sbjct 863 RMRTTNPKET---------KIVIDTTGSTKPKQDDLI---LTCFRGWVKQLQID-YK--- 906
Query 5821 AVASKILGLPTQTVDSSQGSEYDYVI---FTQTTETAHSCNVNRFNVAITRAKIGIL 5874
G T +SQG V + ++ NV +TR + I+
Sbjct 907 -------GNEIMTAAASQGLTRKGVYAVRYKVNENPLYAPTSEHVNVLLTRTEDRIV 956
>sp|P36327|POLN_EEVV3 Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain 3880) OX=36382 PE=3 SV=3
Length=2485
Score = 105 bits (263), Expect = 2e-20, Method: Composition-based stats.
Identities = 54/162 (33%), Positives = 69/162 (43%), Gaps = 30/162 (19%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ + DI +A VI+NAAN + GGGV GAL K ES D
Sbjct 1329 CAPSYHVVRGDIA----TATEGVIINAANSKGQPGGGVCGALYKKF-----PESFDL--- 1376
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQ---LLKAAYE------NFNSQDIL 1122
P+ VG + L+ G AK +H VGPN N +I+ L AYE N N+ +
Sbjct 1377 -QPIEVGKARLVKG--AAKHIIHAVGPNFNKVSEIEGDKQLAEAYESIAKIVNDNNYKSV 1433
Query 1123 LAPLLSAGIFGA------KPLQSLQVCVQTVRTQVYIAVNDK 1158
PLLS GIF + L L + T V I DK
Sbjct 1434 AIPLLSTGIFSGNKDRLTQSLNHLLTALDTTDADVAIYCRDK 1475
Score = 51.2 bits (121), Expect = 4e-04, Method: Composition-based stats.
Identities = 58/297 (20%), Positives = 92/297 (31%), Gaps = 62/297 (21%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS G+ + + + + + C+ II R
Sbjct 719 VYGVPGSGKS----GIIKSAVTKKDLVVSA----------------KKENCAEIIRDVKR 758
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
++ D VN+ V + + + DE L + A +R K V
Sbjct 759 IKGLD---VNARTVDSVLLNG---CKYPVETLYIDEAFACHAGTLRALIAIIRPKKAVLC 812
Query 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
GDP Q + K E V RRC + VS L YD
Sbjct 813 GDPKQCGFFNMMCLKVHFNHEICTQVFHK----------SISRRCTKSVTSVVSTLFYDK 862
Query 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
+++ K I D + + Q ++ LT W K + I Y
Sbjct 863 RMRTTNPKET---------KIEIDTTGSTKPKQDDLI---LTCFRGWVKQLQID-YK--- 906
Query 5821 AVASKILGLPTQTVDSSQGSEYDYVI---FTQTTETAHSCNVNRFNVAITRAKIGIL 5874
G T +SQG V + ++ NV +TR + I+
Sbjct 907 -------GNEVMTAAASQGLTRKGVYAVRYKVNENPLYAPTSEHVNVLLTRTEDRIV 956
>sp|P27282|POLN_EEVVT Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain Trinidad donkey) OX=11038 PE=1 SV=3
Length=2493
Score = 105 bits (262), Expect = 2e-20, Method: Composition-based stats.
Identities = 53/162 (33%), Positives = 69/162 (43%), Gaps = 30/162 (19%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ + DI +A VI+NAAN + GGGV GAL K ES D
Sbjct 1329 CAPSYHVVRGDIA----TATEGVIINAANSKGQPGGGVCGALYKKF-----PESFDL--- 1376
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQ---LLKAAYE------NFNSQDIL 1122
P+ VG + L+ G AK +H VGPN N +++ L AYE N N+ +
Sbjct 1377 -QPIEVGKARLVKG--AAKHIIHAVGPNFNKVSEVEGDKQLAEAYESIAKIVNDNNYKSV 1433
Query 1123 LAPLLSAGIFGA------KPLQSLQVCVQTVRTQVYIAVNDK 1158
PLLS GIF + L L + T V I DK
Sbjct 1434 AIPLLSTGIFSGNKDRLTQSLNHLLTALDTTDADVAIYCRDK 1475
Score = 52.0 bits (123), Expect = 3e-04, Method: Composition-based stats.
Identities = 58/297 (20%), Positives = 90/297 (30%), Gaps = 62/297 (21%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS G+ + + + + + C+ II
Sbjct 719 VYGVPGSGKS----GIIKSAVTKKDLVVSA----------------KKENCAEIIRD--- 755
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
V+ VN+ V + + + DE L + A +R K V
Sbjct 756 VKKMKGLDVNARTVDSVLLNG---CKHPVETLYIDEAFACHAGTLRALIAIIRPKKAVLC 812
Query 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
GDP Q + K E V RRC + VS L YD
Sbjct 813 GDPKQCGFFNMMCLKVHFNHEICTQVFHK----------SISRRCTKSVTSVVSTLFYDK 862
Query 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
K++ K I D + + Q ++ LT W K + I Y
Sbjct 863 KMRTTNPKET---------KIVIDTTGSTKPKQDDLI---LTCFRGWVKQLQID-YK--- 906
Query 5821 AVASKILGLPTQTVDSSQGSEYDYVI---FTQTTETAHSCNVNRFNVAITRAKIGIL 5874
G T +SQG V + ++ NV +TR + I+
Sbjct 907 -------GNEIMTAAASQGLTRKGVYAVRYKVNENPLYAPTSEHVNVLLTRTEDRIV 956
>sp|Q8V294|POLN_EEVVC Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain CPA201) OX=376610 PE=3 SV=3
Length=2497
Score = 105 bits (262), Expect = 2e-20, Method: Composition-based stats.
Identities = 77/276 (28%), Positives = 104/276 (38%), Gaps = 50/276 (18%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ + DI +A VIVNAAN + G GV GAL + ES D
Sbjct 1329 CAPSYHVVRGDIA----TATEGVIVNAANSKGQPGSGVCGALYRK-----YPESFDL--- 1376
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQ---LLKAAYE------NFNSQDIL 1122
P+ VG + L+ G++ K +H VGPN N +++ L AYE N N+ +
Sbjct 1377 -QPIEVGKARLVKGNS--KHLIHAVGPNFNKVSEVEGDKQLAEAYESIARIINDNNYRSV 1433
Query 1123 LAPLLSAGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRV 1176
PLLS GIF + L L + T V I DK L + R
Sbjct 1434 AIPLLSTGIFAGNKDRLMQSLNHLLTALDTTDADVAIYCRDKKW-----EVTLKEVVARR 1488
Query 1177 EAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTT------LEETKFLTNKLL 1230
EA EE +EDS E V K + T+ LE TKF
Sbjct 1489 EA--VEEICISEDSSVAEPDAELVRVHPKSSLAGRKGYSTSDGKTFSYLEGTKF-HQAAK 1545
Query 1231 LFADINGKLYHDSQN------MLRGEDMSFLEKDAP 1260
A+IN ++ + GE MS + P
Sbjct 1546 DMAEINAMWPAATEANEQVCLYILGESMSSIRSKCP 1581
Score = 49.7 bits (117), Expect = 0.002, Method: Composition-based stats.
Identities = 36/192 (19%), Positives = 60/192 (31%), Gaps = 36/192 (19%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS G+ + + + + + C+ II
Sbjct 719 VYGVPGSGKS----GIIKSAVTKKDLVVSA----------------KKENCAEIIRD--- 755
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
V+ VN+ V + + + DE L + A +R K V
Sbjct 756 VKKMKGLDVNARTVDSVLLNG---CKHPVETLYIDEAFACHAGTLRALIAIIRPKKAVLC 812
Query 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
GDP Q + K E V RRC + VS L YD
Sbjct 813 GDPKQCGFFNMMCLKVHFNHEICTQVFHK----------SISRRCTKSVTSVVSTLFYDK 862
Query 5761 KLKAHKDKSAQC 5772
+++ + ++
Sbjct 863 RMRTTNPRDSKI 874
>sp|Q9WJC7|POLN_EEVVM Polyprotein P1234 OS=Venezuelan equine encephalitis
virus (strain Mena II) OX=36384 PE=3 SV=3
Length=2499
Score = 105 bits (262), Expect = 2e-20, Method: Composition-based stats.
Identities = 76/276 (28%), Positives = 102/276 (37%), Gaps = 50/276 (18%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ + DI +A VIVNAAN + G GV GAL + ES D
Sbjct 1329 CAPSYHVVRGDIA----TATEGVIVNAANSKGQPGSGVCGALYRK-----YPESFDL--- 1376
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQ---LLKAAYE------NFNSQDIL 1122
P+ VG + L+ G + K +H VGPN + +++ L AYE N N+ +
Sbjct 1377 -QPIEVGKARLVKGSS--KHIIHAVGPNFSKVSEVEGDKQLAEAYESIAKIINDNNYRSV 1433
Query 1123 LAPLLSAGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRV 1176
PLLS GIF + L L + T V I DK L + R
Sbjct 1434 AIPLLSTGIFAGNKDRLMQSLNHLLTALDTTDADVAIYCRDKKW-----EVTLKEVVARR 1488
Query 1177 EAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTT------LEETKFLTNKLL 1230
EA EE +EDS E V K + T+ LE TKF
Sbjct 1489 EA--VEEICISEDSSVAEPDAELVRVHPKSSLAGRKGYSTSDGKTFSYLEGTKF-HQAAK 1545
Query 1231 LFADING------KLYHDSQNMLRGEDMSFLEKDAP 1260
A+IN + + GE MS + P
Sbjct 1546 DMAEINAMWPTATEANEQVCLYILGESMSSIRSKCP 1581
Score = 51.2 bits (121), Expect = 5e-04, Method: Composition-based stats.
Identities = 54/297 (18%), Positives = 89/297 (30%), Gaps = 62/297 (21%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS G+ + + + + + C+ II
Sbjct 719 VYGVPGSGKS----GIIKSAVTKKDLVVSA----------------KKENCAEIIRD--- 755
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
V+ VN+ V + + + DE L + A +R K V
Sbjct 756 VKKMKGLDVNARTVDSVLLNG---CKHPVETLYIDEAFACHAGTLRALIAIIRPKKAVLC 812
Query 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
GDP Q + K E V RRC + VS L YD
Sbjct 813 GDPKQCGFFNMMCLKVHFNHEICTQVFHK----------SISRRCTKSVTSVVSTLFYDK 862
Query 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
+++ + ++ S ++ + LT W K + I Y
Sbjct 863 RMRTTNPRDSKI--------EIDTTGSTKSKKE----DLILTCFRGWVKQLQID-YK--- 906
Query 5821 AVASKILGLPTQTVDSSQGSEYDYVI---FTQTTETAHSCNVNRFNVAITRAKIGIL 5874
G T +SQG V + ++ NV +TR + I+
Sbjct 907 -------GNEIMTAAASQGLTRKSVYAVRYKVNENPLYAPTSEHVNVLLTRTEDKIV 956
>sp|Q60560|SMBP2_MESAU DNA-binding protein SMUBP-2 OS=Mesocricetus
auratus OX=10036 GN=IGHMBP2 PE=1 SV=1
Length=989
Score = 104 bits (259), Expect = 3e-20, Method: Composition-based stats.
Identities = 62/257 (24%), Positives = 90/257 (35%), Gaps = 41/257 (16%)
Query 5664 LPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYF 5723
LPE D+VV DE + A + S L+A + GD QLP P T+ K L
Sbjct 363 LPENHFDVVVVDECAQA--LEASCWIPLLKAPKCILAGDHRQLP-PTTISHKAALAGLSR 419
Query 5724 NSVCRLMKT--IGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVI 5781
+ + RL++ G L R I S +Y +L AH + K
Sbjct 420 SLMERLVEKHGAGAVRMLTVQYRMHQAITRWASEAMYHGQLTAHPSVAGHLLKDLPGVAD 479
Query 5782 THDVS--------SAINRPQIGVVREFLTRNPAW------------------RKAVFISP 5815
T + S + ++ NP I+P
Sbjct 480 TEETSVPLLLIDTAGCGLLELDEEDSQSKGNPGEVRLVTLHIQALVDAGVHAGDIAVIAP 539
Query 5816 YNSQNAVASKILG-----LPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVA 5865
YN Q + + L L ++VD QG E + VI T + E R NVA
Sbjct 540 YNLQVDLLRQSLSNKHPELEIKSVDGFQGREKEAVILTFVRSNRKGEVGFLAEDRRINVA 599
Query 5866 ITRAKIGILCIMSDRDL 5882
+TRA+ + I R +
Sbjct 600 VTRARRHVAVICDSRTV 616
Score = 49.3 bits (116), Expect = 0.002, Method: Composition-based stats.
Identities = 17/52 (33%), Positives = 27/52 (52%), Gaps = 2/52 (4%)
Query 5573 VGMQKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKA 5622
+ ++ + + GPPGTGK+ I L +I+ A S+ AVD L E+
Sbjct 203 LAQKEVAIIHGPPGTGKTTTVVEIILQAVKQGLKILCCAPSNVAVDNLVERL 254
>sp|E9QAM5|HELZ2_MOUSE 3'-5' exoribonuclease HELZ2 OS=Mus musculus
OX=10090 GN=Helz2 PE=1 SV=1
Length=2947
Score = 102 bits (254), Expect = 2e-19, Method: Composition-based stats.
Identities = 59/299 (20%), Positives = 101/299 (34%), Gaps = 68/299 (23%)
Query 5672 VVFDEISMATNYD--LSVVNARLRAKHYVYIGDPAQLPA--PRTLLTKGTLEPEYFNSVC 5727
++ DE MAT + + +V + V +GD QL L ++ F
Sbjct 2654 ILIDEAGMATEPETLIPLVCFSKTVEKVVLLGDHKQLRPVVKSEQLQSLGMDRSLFERYH 2713
Query 5728 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITH---- 5783
R + L T R +I S Y KLK D + + G +
Sbjct 2714 R------DAIMLDTQYRMHKDICSFPSVEFYGGKLKTWSDLRRLPSILGHTGKPSCSVIF 2767
Query 5784 -----------------DVSSAINRPQIGVVREFLTRNPAWR-----KAVFISPYNSQNA 5821
+ +S N ++ V + + R ++PYN+Q A
Sbjct 2768 GSVQGHEQKLLVSTEDGNENSRANPEEVTQVVRIIKQLTLDRTVDPKDIAVLTPYNAQAA 2827
Query 5822 VASK------ILGLPTQTVDSSQGSEYDYVIFTQTTE------------------TAHSC 5857
S+ + G+ ++ SQGSE+ YVI +
Sbjct 2828 AISRGLMQRGVTGVTVTSITKSQGSEWRYVIVSTVRTCPRSDVDQRPTKSWLKKFLGFVV 2887
Query 5858 NVNRFNVAITRAKIGILCIMSDRDL-------YDKLQFTSLEIPRRNVATLQAENVTGL 5909
+ ++ NVAITRA+ LCI+ D L + L F + + ++ + + L
Sbjct 2888 DPHQVNVAITRAQEA-LCIIGDHLLLRCCPLWHRLLDFCEAQHSLVSAEKVRVQRKSAL 2945
Score = 66.2 bits (160), Expect = 2e-08, Method: Composition-based stats.
Identities = 60/381 (16%), Positives = 108/381 (28%), Gaps = 75/381 (20%)
Query 5580 TLQGPPGTGKSHFAIGLAL---YYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5636
+ GP GTGK++ AL P +++ +++A D + P
Sbjct 787 LIYGPFGTGKTYTLAMAALEVVQQPHTKVLICTHTNSAADIYIREYFHDYVSSGHPEATP 846
Query 5637 ARARVECFDKFKVNSTLEQY------------------------VFCTVNA----LPETT 5668
R + + T QY V T A +P
Sbjct 847 LRVMYADRPPRQTDPTTLQYCCLTEDRQAFRPPTGPELVHHRLVVTTTSQARELQVPAGF 906
Query 5669 ADIVVFDEISMATNYDLSVVNA-RLRAKHYVYIGDPAQLPA-----PRTLLTKGTLEPEY 5722
+ DE + + + + L V GD Q+ PR + TL
Sbjct 907 FSHIFIDEAAQMLECEALIPLSYALSLTRVVLAGDHMQVTPRLFSVPRDKSARHTLLHRL 966
Query 5723 FNSVCRLMKTIGPD--MFLGTCRRCPAEIVDTVSALVYDNKLKA-----HKDKSAQCFKM 5775
F + I + R A I++ VS Y K + Q + +
Sbjct 967 FLYYQQEAHKIAQQSRIIFHENYRSTAAIINFVSHHFYLAKGNPIQASGKVPRHPQHYPL 1026
Query 5776 FY---KGVITHDVS--SAINRPQIGVVREFLTR-NPAW------RKAVFISPYN------ 5817
+ G D+S S +N ++ V E + W R+ I +
Sbjct 1027 MFCHVAGSPEQDMSMTSWLNSAEVTQVVEKVREIYNTWPHCWGPREQRHICAVSHGAQVS 1086
Query 5818 --SQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTE-----------TAHSCNVNRFNV 5864
Q + + + + G E+ V+ + + N
Sbjct 1087 ALRQELRRRNLGEVSVGSFEILPGREFRVVVLSSVHNRNSLLSPGAPTSEFFTEPRVLNT 1146
Query 5865 AITRAKIGILCIMSDRDLYDK 5885
+TRA+ ++ + L
Sbjct 1147 VMTRAQSQLVAVGDAVALCSS 1167
>sp|Q008X5|R1A_WBV24 Replicase polyprotein 1a OS=White bream virus
(isolate Blicca bjoerkna L./Germany/DF24/00) OX=766180
GN=1a PE=1 SV=1
Length=4555
Score = 102 bits (254), Expect = 2e-19, Method: Composition-based stats.
Identities = 23/98 (23%), Positives = 35/98 (36%), Gaps = 9/98 (9%)
Query 4283 QAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTL 4342
AI+ P + ++ G S C C DH C G +VQIP ++ F L
Sbjct 4467 IAISQVPVQTIGYLTYAGISVCRQCATKQDHT-----CQYAGYFVQIPREHVSN--IFNL 4519
Query 4343 RNTVCTVCGMWKGYGCSCDQLREPLMQSADASTFLNRV 4380
+T C K +C L++ + V
Sbjct 4520 TDT--PPCLHNKFTCTTCQPLQQQSKTQQPPLNWWGSV 4555
Score = 56.6 bits (135), Expect = 1e-05, Method: Composition-based stats.
Identities = 119/804 (15%), Positives = 242/804 (30%), Gaps = 120/804 (15%)
Query 2998 VDAMNLIANIFTPLVQPVGALDVSASVVAGGII---AILVTCAAYYFMKFRRVFGEYNHV 3054
+ L + + V+ L AS ++ ++++ +Y + +F Y +
Sbjct 3219 SNTKKLCVQVGSNAVRCASVLPTGASSNVAALLMASVVVISMVLFYLYLLQ-IFKFYTNS 3277
Query 3055 VAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVP 3114
V + ++ L++ + + ++ + Y Y +++ + ++
Sbjct 3278 VIMSFVIQLLTLLATTVSTPLAVTVQLFVITYGY--------TNWILLTLSLLNLTVLLS 3329
Query 3115 FWITAIYVFCISLKHCHWFFNNYLRKRVMFNGVTF---STFEEAALCTFLLNKEMYLKLR 3171
+ +V L + F + + V G T +FE+ A TF L ++L
Sbjct 3330 TPVGITFVVIYGLYKAYTLFTSSGQGCVYNEGGTIRFSGSFEQVANSTFPLTNASCVQLL 3389
Query 3172 SETLLPLTQYNRYLALYNKYKYFSGALDTTSYREAACCHLAKALNDFSNSGADVLYQPPQ 3231
S+ + Q N Y + ++ + R A L + L+ S +LY+
Sbjct 3390 SDLGITYQQLNVYASSRDR-----------NVRRLAQALLHRQLDSASEC---ILYE--G 3433
Query 3232 TSITSAVLQSGFRKMAFPSGKVEGCMVQVT-CGTTTLNGLWLD---------DTVYCPRH 3281
S + Q+ R + V + + NG+ L + + C H
Sbjct 3434 CSGNTITRQALQRIRQAVTVVVTPASQNLCKITSNQANGIGLSCTGTFFTSTEIITCA-H 3492
Query 3282 VICTAEDML---NPNYEDLLIRKSNHSFLVQAGNVQLRVIGHSMQNCLLRLKVDTSNPKT 3338
I T++ Y+ + +N ++ V L V + + + +
Sbjct 3493 GIGTSDITAVHKGITYDCKVKSINNDIAILITTTVNLSVQNIKLDSSFSQKSDNYQRNFV 3552
Query 3339 PKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNHTIKGSFLNGSCGSVGFNIDYDCVS 3398
FV Q ++ + H G GS + ++ + +
Sbjct 3553 QFVSFVDQQNSDAVTINN----------TVMLPSGHFFAIGTEAGESGSP-YTLNGNII- 3600
Query 3399 FCYMHHMELPTGVHAGTDLEGKFY------GPFVDRQTAQAAGTDTTITLNVLAWLYAAV 3452
G+H G D G + G F T T + + A + A+
Sbjct 3601 -----------GIHYGIDNAGSWMLASRPDGSFYVPATQHGNSAKVTFSTDAFAQQFPAI 3649
Query 3453 INGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCAALKELL 3512
+ T+ N +A N D D V + LK L
Sbjct 3650 V--------TNKTSDQLVNEIAATNN-TAFELDTTD------------VSHLSNLLKHLK 3688
Query 3513 QNGMNGRTILGSTILEDEFTPFDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILV 3572
N + L D V +Q S VT V + L S +I
Sbjct 3689 NNNETPK------SLSDYLPVAPVTQQTS-VTVGQTLTSPVNNMQTALYTLMLVSEVITY 3741
Query 3573 QSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYM 3632
T N+ L + + +A K + L ++ T + +
Sbjct 3742 ILT---------PNSDLSVLISMFVTSAFLKFGAS-KLFYNTEMLRNTITTFVVYRYTTL 3791
Query 3633 PASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVI 3692
+ V L+ + + + L+L+T R VY + + + + +I
Sbjct 3792 LIALVFSQYYLHILSYALKLNTLVLTVIALTFLVTPLVLLTIRRVYYYSQNYLISCVFII 3851
Query 3693 TLV--YKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITG 3750
+ + D + +IS + + + I F + P
Sbjct 3852 SCFASHTYTLYILTDTTVDFQTFIIS------EPIFSTLLCNLFIGFTLISVVPNPLYVC 3905
Query 3751 NTLQCIMLVYCFLGYCCCCYFGLF 3774
I+L LG+ C+ +
Sbjct 3906 VVFMYILLDCEALGFIVTCFMASY 3929
Score = 50.1 bits (118), Expect = 0.001, Method: Composition-based stats.
Identities = 42/200 (21%), Positives = 61/200 (31%), Gaps = 37/200 (19%)
Query 1004 NQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAM-- 1061
N F + V +I + IVNAAN L +G GV GA+ A + +
Sbjct 1642 NPFAS----NEGVTFAVHNIGAITTTEGE-FIVNAANKQLNNGTGVTGAIFAAHDKELKL 1696
Query 1062 ---------QKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPN------------- 1099
SD + + A LH P
Sbjct 1697 TQAIKALPTYGASDKLESHQHVVQT--IIKNNNSTHAINILHAAAPIKVKCTSKNPEVLL 1754
Query 1100 -LNAGEDIQLLKAA-----YENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYI 1153
N +L + Y N + PL AG +G KPL SL+ + +R +
Sbjct 1755 AHNETAQSELKETYKAIVDYAQLNKLTHIYLPLFGAGAYGHKPLDSLEAFLDAMRNRSPQ 1814
Query 1154 AVNDKALYEQVVMDYLDNLK 1173
+ L + LDN
Sbjct 1815 STTQYTLLLSDPVKPLDNPS 1834
Score = 39.7 bits (91), Expect = 1.8, Method: Composition-based stats.
Identities = 52/341 (15%), Positives = 91/341 (27%), Gaps = 59/341 (17%)
Query 2110 VPWSKILAYVKPFLGQAAITTSNCAKRLAQRVFNNYMPYVFTLLFQLCTFTKST--NSRI 2167
+S LAY+ + Y+ T T+ T + I
Sbjct 2551 CTFSVFLAYIALLYSFSGHGIFTVVAYFTMLFARYYITSFINFCTSQLTATQVTQWFAAI 2610
Query 2168 RASLPTTIAKNSVKSVAKLCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAF 2227
+A + + + + Y+ K+S + T+ M++ ++
Sbjct 2611 KAKYTGIYESSQDRVLTVNVTGTNVPYI--VKYSTILTVTMYVAFMAFVWTVSTYAAQYT 2668
Query 2228 G-----------VLLSNFGAPSYCNGVRELYLNSSNVTTMDFCE--GSFPCSI-CLSGLD 2273
V V Y +S + C S C +
Sbjct 2669 AGERYDRPPYQTVFQKTLNVLGLTETVTYYYPYAS---LNEACAASTSILCRLGSPFNFH 2725
Query 2274 SLDSYPALETIQVTISSYKLDLTILGLAAEWVLAYMLFTKFFYLLGLSAIMQVFFGYFAS 2333
Y + T+Q SS + LF F L ++ +
Sbjct 2726 YPSDYTQVRTVQTDTSS----------------PFWLFIIFMPPSFLFIVLPWLILCTIT 2769
Query 2334 HFISNSWLMWFIISIVQMAPVSAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMMCYKRN 2393
+SI Q+ S ++ I F Y K H C TC+ +
Sbjct 2770 P----------TVSIAQLLVPSIILNATIVF--IYIRRKFTGHC---CGPHTCIKHADIS 2814
Query 2394 RATRVECTTIVNGMKRSFYVYANGGRGFCKTHNWNCLNCDT 2434
R+ + T+ + C HNW C N D+
Sbjct 2815 RSLQFRPTSQIQHSLTFC-------GTLCAKHNWYCNNSDS 2848
>sp|O59182|Y1513_PYRHO Uncharacterized protein PH1513 OS=Pyrococcus
horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974
/ NBRC 100139 / OT-3) OX=70601 GN=PH1513 PE=4 SV=1
Length=190
Score = 92.8 bits (229), Expect = 3e-19, Method: Composition-based stats.
Identities = 42/171 (25%), Positives = 73/171 (43%), Gaps = 23/171 (13%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKES----DDYIKL 1071
I DI K IVNAAN +L+HGGGVA A+ KA +G + + + ++ +
Sbjct 5 FKIVRGDITK----FRAEAIVNAANKYLEHGGGVAYAIAKAASGDVSEYTRISKEEMRRQ 60
Query 1072 NGP--LTVGGSCLLSGHNLA----KKCLHVVGP----NLNAGEDIQLLKAAYENFNSQD- 1120
G + G + L K +H VGP + ++ +L A D
Sbjct 61 LGKDWIEHGEVVVTPPMKLKENGVKYVIHTVGPYCGGVWSKDKEEKLKLAILGALKKADE 120
Query 1121 ----ILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMD 1167
+ P +SAGI+G + ++ + V+ + +A + K +Y + +
Sbjct 121 LGVKSIAFPAISAGIYGCPLKEVVRTFKEVVKEFLKVANHVKEVYLVLYSE 171
>sp|Q9EQN5|SMBP2_RAT DNA-binding protein SMUBP-2 OS=Rattus norvegicus
OX=10116 GN=Ighmbp2 PE=1 SV=1
Length=988
Score = 99.0 bits (245), Expect = 1e-18, Method: Composition-based stats.
Identities = 61/257 (24%), Positives = 88/257 (34%), Gaps = 41/257 (16%)
Query 5664 LPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYF 5723
LPE D+VV DE + A + S L+A + GD QLP P T+ K L
Sbjct 363 LPEDYFDVVVVDECAQA--LEASCWIPLLKAPKCILAGDHKQLP-PTTVSHKAALAGLSR 419
Query 5724 NSVCRLMKTIGP--DMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVI 5781
+ + RL + G L R I S +Y +L AH + K
Sbjct 420 SLMERLAEKHGAAVVRMLAVQYRMHQAITRWASEAMYHGQLTAHPSVAGHLLKDLPGVAD 479
Query 5782 THDVS--------SAINRPQIGVVREFLTRNPAW------------------RKAVFISP 5815
T + S + ++ NP I+P
Sbjct 480 TEETSVPLLLIDTAGCGLLELEEEDSQSKGNPGEVRLVTLHIQALVDAGVQAGDIAVIAP 539
Query 5816 YNSQNAVASKILG-----LPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVA 5865
YN Q + + L L ++VD QG E + VI T + E R NVA
Sbjct 540 YNLQVDLLRQSLSNKHPELEIKSVDGFQGREKEAVILTFVRSNRKGEVGFLAEDRRINVA 599
Query 5866 ITRAKIGILCIMSDRDL 5882
+TRA+ + I +
Sbjct 600 VTRARRHVAVICDSHTV 616
Score = 49.3 bits (116), Expect = 0.002, Method: Composition-based stats.
Identities = 16/52 (31%), Positives = 27/52 (52%), Gaps = 2/52 (4%)
Query 5573 VGMQKYSTLQGPPGTGKSH--FAIGLALYYPSARIVYTACSHAAVDALCEKA 5622
+ ++ + + GPPGTGK+ I L +++ A S+ AVD L E+
Sbjct 203 LAQKEVAIIHGPPGTGKTTTVVEIILQAVKQGLKVLCCAPSNIAVDNLVERL 254
>sp|Q9V0Y3|Y656_PYRAB Uncharacterized protein PYRAB06560 OS=Pyrococcus
abyssi (strain GE5 / Orsay) OX=272844 GN=PYRAB06560
PE=4 SV=2
Length=183
Score = 89.0 bits (219), Expect = 5e-18, Method: Composition-based stats.
Identities = 44/176 (25%), Positives = 70/176 (40%), Gaps = 32/176 (18%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQK----ESDDYIKLNG 1073
+ DI + IVNAAN +L+HGGGVA A+ KA +G + + ++ K G
Sbjct 4 VVHGDITR----FKAEAIVNAANKYLEHGGGVAYAIAKAASGDVSEYIRISKEEMRKQIG 59
Query 1074 P--LTVGGSCLLSGHNLA----KKCLHVVGP----NLNAGEDIQLLKAAYENFNSQD--- 1120
+ G + NLA K +H VGP + + +L A D
Sbjct 60 RDWIEHGEVVVTPPLNLAKNGVKYVIHTVGPYCGGKWDEDKRKKLELAILGALKKADELG 119
Query 1121 --ILLAPLLSAGIFGAKPLQSLQVCVQTVRT---------QVYIAVNDKALYEQVV 1165
+ P +SAGI+G + ++ V VY+ + + YE +
Sbjct 120 VRSIAFPAISAGIYGCPLEEVVKTFKLVVNEFLKSAKNVTDVYLVLYSERDYEVAL 175
>sp|O28751|Y1521_ARCFU ADP-ribose glycohydrolase AF_1521 OS=Archaeoglobus
fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628
/ NBRC 100126 / VC-16) OX=224325 GN=AF_1521 PE=1 SV=2
Length=192
Score = 88.2 bits (217), Expect = 1e-17, Method: Composition-based stats.
Identities = 41/179 (23%), Positives = 70/179 (39%), Gaps = 30/179 (17%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKES----DDYIKL 1071
+ + DI + IVNAAN L+HGGGVA A+ KA G + +
Sbjct 14 LKLAQGDITQ----YPAKAIVNAANKRLEHGGGVAYAIAKACAGDAGLYTEISKKAMREQ 69
Query 1072 NGP--LTVGGSCLLSGHNLA----KKCLHVVGPNLNAGEDIQLLKAAYENFN-------- 1117
G + G + NL K H VGP + +L + Y+ F
Sbjct 70 FGRDYIDHGEVVVTPAMNLEERGIKYVFHTVGPICSGMWSEELKEKLYKAFLGPLEKAEE 129
Query 1118 -SQDILLAPLLSAGIFGAKPLQSLQVCVQTVR-------TQVYIAVNDKALYEQVVMDY 1168
+ + P +SAGI+G + ++ ++ V+ +V + + D+ E + +
Sbjct 130 MGVESIAFPAVSAGIYGCDLEKVVETFLEAVKNFKGSAVKEVALVIYDRKSAEVALKVF 188
>sp|Q09449|YQ12_CAEEL Uncharacterized ATP-dependent helicase C05C10.2
OS=Caenorhabditis elegans OX=6239 GN=C05C10.2 PE=3 SV=2
Length=1523
Score = 95.9 bits (237), Expect = 1e-17, Method: Composition-based stats.
Identities = 60/241 (25%), Positives = 93/241 (39%), Gaps = 31/241 (13%)
Query 5668 TADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTL-EPEYFNSV 5726
V DE S L + + IGD QLP +G L + N++
Sbjct 1174 DVCAVQIDEASQLAECTLLGLLKSFNNASFGLIGDIHQLPPYCEEGLEGKLKDFGIGNTM 1233
Query 5727 CRLMKT-IGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQC------------- 5772
R +K + P L RC + + +S L YD L + + A+
Sbjct 1234 ERAIKEKMFPVCTLRNVYRCHPKTTELLSELFYDGALVSGVSELARSDFMTKRDDFWPNP 1293
Query 5773 -FKMFYKGVITHDV---SSAINRPQIGVVREFLT------RNPAW-RKAVFISPYNSQNA 5821
F M + +S N + +V E + RNP IS Y++Q +
Sbjct 1294 KFPMMFVNNTGASTKMGTSTSNSSEKSIVGEIVQNLINDPRNPVNPSDIGVISFYSAQTS 1353
Query 5822 VASKIL---GLPTQTVDSSQGSEYDYVIFTQTTE--TAHSCNVNRFNVAITRAKIGILCI 5876
+ ++ L G+ TVD+ QGSE + +I T E + NR NVA++RAK + I
Sbjct 1354 ILTEHLRGSGVKCGTVDAFQGSEKEIIIMCSTNERISDFMQLSNRLNVAMSRAKQVTIII 1413
Query 5877 M 5877
Sbjct 1414 G 1414
>sp|P40694|SMBP2_MOUSE DNA-binding protein SMUBP-2 OS=Mus musculus
OX=10090 GN=Ighmbp2 PE=1 SV=1
Length=993
Score = 95.1 bits (235), Expect = 2e-17, Method: Composition-based stats.
Identities = 57/266 (21%), Positives = 87/266 (33%), Gaps = 44/266 (17%)
Query 5664 LPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYF 5723
LPE D+VV DE + A + S L+A + GD QLP P T+ + L
Sbjct 363 LPEDYFDVVVVDECAQA--LEASCWIPLLKAPKCILAGDHRQLP-PTTVSHRAALA-GLS 418
Query 5724 NSVCRLMKT---IGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGV 5780
S+ + G L R I+ S +Y + +H + K
Sbjct 419 RSLMERLAEKHGAGVVRMLTVQYRMHQAIMCWASEAMYHGQFTSHPSVAGHLLKDLPGVT 478
Query 5781 ITHDVS--------SAINRPQIGVVREFLTRNPAW------------------RKAVFIS 5814
T + + ++ NP I+
Sbjct 479 DTEETRVPLLLIDTAGCGLLELEEEDSQSKGNPGEVRLVTLHIQALVDAGVQAGDIAVIA 538
Query 5815 PYNSQNAVASKILG-----LPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNV 5864
PYN Q + + L L ++VD QG E + V+ T + E R NV
Sbjct 539 PYNLQVDLLRQSLSNKHPELEIKSVDGFQGREKEAVLLTFVRSNRKGEVGFLAEDRRINV 598
Query 5865 AITRAKIGILCIMSDRDLYDKLQFTS 5890
A+TRA+ + I D + F
Sbjct 599 AVTRARRHVAVI-CDSHTVNNHAFLE 623
Score = 49.3 bits (116), Expect = 0.002, Method: Composition-based stats.
Identities = 20/78 (26%), Positives = 36/78 (46%), Gaps = 10/78 (13%)
Query 5555 PTLNIS--DEFSSNVANYQK------VGMQKYSTLQGPPGTGKSH--FAIGLALYYPSAR 5604
P + I +++ + QK + ++ + + GPPGTGK+ I L +
Sbjct 177 PAMEIPPLSFYNTTLDLSQKEAVSFALAQKELAIIHGPPGTGKTTTVVEIILQAVKQGLK 236
Query 5605 IVYTACSHAAVDALCEKA 5622
++ A S+ AVD L E+
Sbjct 237 VLCCAPSNIAVDNLVERL 254
>sp|Q9BYK8|HELZ2_HUMAN 3'-5' exoribonuclease HELZ2 OS=Homo sapiens
OX=9606 GN=HELZ2 PE=1 SV=7
Length=2896
Score = 93.6 bits (231), Expect = 8e-17, Method: Composition-based stats.
Identities = 58/265 (22%), Positives = 92/265 (35%), Gaps = 62/265 (23%)
Query 5672 VVFDEISMATNYDLSVVNARL--RAKHYVYIGDPAQLPA--PRTLLTKGTLEPEYFNSVC 5727
++ DE MAT + +++ +A+ V +GD QL L L+ F
Sbjct 2604 ILVDEAGMATEPE-TLIPLVQFPQAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYH 2662
Query 5728 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK--------------AHKDKSAQCF 5773
L T R I S Y +KLK A K+ F
Sbjct 2663 E------DAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIF 2716
Query 5774 KMFYKGVITH-------DVSSAINRPQIGVVREFLTRNPAWR-----KAVFISPYNSQNA 5821
+ + +S N ++ V + R ++PYN+Q +
Sbjct 2717 GHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQAS 2776
Query 5822 VASKIL------GLPTQTVDSSQGSEYDYVIFTQTTETA------------------HSC 5857
SK L G+ ++ SQGSE+ YV+ + A
Sbjct 2777 EISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVV 2836
Query 5858 NVNRFNVAITRAKIGILCIMSDRDL 5882
+ N+ NVA+TRA+ G LC++ D L
Sbjct 2837 DPNQVNVAVTRAQEG-LCLIGDHLL 2860
Score = 60.1 bits (144), Expect = 1e-06, Method: Composition-based stats.
Identities = 59/383 (15%), Positives = 115/383 (30%), Gaps = 85/383 (22%)
Query 5580 TLQGPPGTGKSHFAIGLALYY------PSARIVYTACSHAAVDALCEKALKYLP---IDK 5630
+ GP GTGK+ LA+ P +++ +++A D + +
Sbjct 788 LIYGPFGTGKT---YTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPE 844
Query 5631 CS--RII----------PARARVECFDK----FKVNSTLE-----QYVFCTVNA----LP 5665
+ R++ P + C F+ + E V T A +P
Sbjct 845 ATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQARELRVP 904
Query 5666 ETTADIVVFDEISMATNYD-LSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFN 5724
++ DE + + L+ + V GD Q+ PR E+
Sbjct 905 VGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQV-TPRLFSVARARAAEH-T 962
Query 5725 SVCRLMKTIGPD---------MFLGTCRRCPAEIVDTVSALVY---------DNKLKAHK 5766
+ RL + + RC IV +S Y K+ H
Sbjct 963 LLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHP 1022
Query 5767 DKSAQCFKMFYKG-VITHDVSSAINRPQIGVVREFLT-RNPAW--------RKAVFISPY 5816
F ++S +N +I V E + W ++ + + +
Sbjct 1023 RHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSH 1082
Query 5817 NSQNAVASKIL---GLPTQTVDSSQ---GSEYDYVIFTQTTETA-----------HSCNV 5859
+Q + + L L +V S + G ++ V+ + +
Sbjct 1083 GAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDA 1142
Query 5860 NRFNVAITRAKIGILCIMSDRDL 5882
N +TRA+ ++ + L
Sbjct 1143 RVLNTVLTRAQSQLVVVGDAVAL 1165
>sp|Q6NYU2|HELZ_DANRE Probable helicase with zinc finger domain
OS=Danio rerio OX=7955 GN=helz PE=2 SV=1
Length=1860
Score = 90.1 bits (222), Expect = 9e-16, Method: Composition-based stats.
Identities = 62/393 (16%), Positives = 112/393 (28%), Gaps = 91/393 (23%)
Query 5579 STLQGPPGTGKSHF---AIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5635
+ GP GTGK+ A+ L P +R++ S++A D + L
Sbjct 657 VLIIGPYGTGKTFTLAQAVKHILKQPESRVLICTHSNSAADLYIKDYLHPYVEAGNPHAR 716
Query 5636 PARARVECFDKF-----KVNSTLE-----------------------QYVFCTVNALPET 5667
P RV +++ + T L +
Sbjct 717 P--LRVYFRNRWVKTVHPLVQQYCLISGAHFTFQMPTRQDVERHRVVVVTLSTSQYLCQL 774
Query 5668 T-----ADIVVFDEISMATNYDLSV-VNARLRAKHYVYIGDPAQLPAPRT--LLTKGTLE 5719
++ DE + A + + + +++ V GD QL + L
Sbjct 775 DLEPGIFTHILLDEAAQAMECETIMPLALAVKSTRVVLAGDHMQLSPFVYSEFARERNLH 834
Query 5720 PEYFNSVCRLMKTIGP-DMFLGTCRRCPAEIVDTVSALVYDNKLK------AHKDKSAQC 5772
+ + + P + L R I++ S L Y+ KL HKD
Sbjct 835 VSLLDRLYEHYPSEYPCRILLCENYRSHEAIINYTSDLFYEGKLMASGKQPPHKDFYPLT 894
Query 5773 FKMFYKGVITHDVSSA-INRPQ----IGVVREFLTRNP------AWRKAVFISPYNSQNA 5821
F + S+A N + + V E + P +SPY Q
Sbjct 895 FFTARGEDVQEKNSTAYYNNAEVFEIVERVEEMRKKWPVSWGKLEEGSIGVVSPYADQVF 954
Query 5822 ------VASKILGLPTQTVDSSQGSEYDYVIFTQTT------------------------ 5851
++ + + V + QG ++ + +
Sbjct 955 RIRAELRKKRMSEVSVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTAIKRKEQLVEDSTE 1014
Query 5852 --ETAHSCNVNRFNVAITRAKIGILCIMSDRDL 5882
+ N N AITRA+ + + L
Sbjct 1015 DLDYGFLSNYKLLNTAITRAQSLVAVVGDPIAL 1047
>sp|E9P860|ZNFX1_CAEEL NFX1-type zinc finger-containing protein
1 homolog OS=Caenorhabditis elegans OX=6239 GN=znfx-1 PE=1
SV=1
Length=2443
Score = 86.7 bits (213), Expect = 1e-14, Method: Composition-based stats.
Identities = 58/265 (22%), Positives = 100/265 (38%), Gaps = 43/265 (16%)
Query 5663 ALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEY 5722
L + I++ +E + + +H V IGD QL P + + +
Sbjct 1455 TLEKVGPRILIVEEAAEVLEAHIISAMIS-TVEHVVMIGDHKQLR-PNPAVHELGVAYGL 1512
Query 5723 FNSVCRLMKTIG-PDMFLGTCRRCPAEIVDTVSAL-VYDNKLKAHK-----DKSAQCFKM 5775
S+ + G P L R I D + L YDN A D +
Sbjct 1513 RISMFERLVERGLPFSQLRQQHRMNLTISDKIVKLSFYDNVTDAENVGLYPDVQGMATNL 1572
Query 5776 FYKGVITHDVS----SAINRPQIGV----VREFLTRNPAWRKAVFISPYNSQNAVASK-- 5825
F+ + + S S +N+ +I + V+ L +N V ++ Y++Q + +
Sbjct 1573 FFWSHTSMEESPDEVSWLNKHEISMTVALVKHLLKQNYTTNDIVVLATYSAQKNLMYREY 1632
Query 5826 --ILG-------LPTQTVDSSQGSEYDYVIFTQTTE---------TAHSCNVNRFNVAIT 5867
+ G +P +TVDS QG E VI + NR VA+T
Sbjct 1633 ANVFGSTPDSNVIPVETVDSFQGKERKIVIVSLVRSHRGGRENTGIGFLAVANRICVALT 1692
Query 5868 RAKIGILC------IMSDRDLYDKL 5886
RA+ G+ IM++ +L++K+
Sbjct 1693 RAQHGMYIIGNGAYIMNNSELWNKI 1717
Score = 42.4 bits (98), Expect = 0.22, Method: Composition-based stats.
Identities = 16/63 (25%), Positives = 29/63 (46%), Gaps = 8/63 (13%)
Query 5575 MQKYSTLQGPPGTGKSHFAIGLALYYPSAR--------IVYTACSHAAVDALCEKALKYL 5626
+ S +QGPPGTGK+H + + R I+ +++ +D L E+ + +
Sbjct 1053 KYELSLIQGPPGTGKTHIGVQIVKTILQNRSYWKITEPILVVCFTNSGLDNLLERIYQMI 1112
Query 5627 PID 5629
D
Sbjct 1113 END 1115
>sp|Q8U0P9|Y1536_PYRFU Uncharacterized protein PF1536 OS=Pyrococcus
furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
OX=186497 GN=PF1536 PE=4 SV=1
Length=183
Score = 78.9 bits (193), Expect = 2e-14, Method: Composition-based stats.
Identities = 44/178 (25%), Positives = 73/178 (41%), Gaps = 32/178 (18%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKE---SDD-YIKL 1071
+ + DI K IVNAAN +L+HGGGVA A+ KA G +++ S + +
Sbjct 2 IKVVKGDITK----FRAEAIVNAANKYLEHGGGVAYAIAKAAAGDVREYIRISKEAMREQ 57
Query 1072 NGP--LTVGGSCLLSGHNL----AKKCLHVVGPNLNAGEDI---QLLKAAYENFNSQ--- 1119
G + G + L K +H VGP D LK A +
Sbjct 58 LGKDWIDHGEVVVTPPLQLEKNGVKYVIHTVGPYCGGSWDEDKKSKLKLAILGALKKADE 117
Query 1120 ---DILLAPLLSAGIFGAKPLQSLQVCVQTVRT---------QVYIAVNDKALYEQVV 1165
+ P +SAGI+G + ++ V+ V+ +V++ + + YE+ +
Sbjct 118 LGVKSIAFPAISAGIYGCPLEKVVETFVEVVKEFLPSAKSLREVFLVLYSQEDYEKAL 175
>sp|O67112|Y987_AQUAE Uncharacterized protein aq_987 OS=Aquifex
aeolicus (strain VF5) OX=224324 GN=aq_987 PE=4 SV=1
Length=165
Score = 77.4 bits (189), Expect = 4e-14, Method: Composition-based stats.
Identities = 30/168 (18%), Positives = 61/168 (36%), Gaps = 26/168 (15%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
++ + I + + VIVN AN GGGVA + + +++E+ + P
Sbjct 2 DIKVVKGSITE----VDADVIVNPANSRGLMGGGVAVVIKRLGGEEIEREAVE----KAP 53
Query 1075 LTVGGSCLLSGHNLA-KKCLHVVGPNLNAGEDIQLLKAAYENFN---------SQDILLA 1124
+ VG + L + L K +H P + + + I+
Sbjct 54 IPVGSAVLTTAGKLKFKGVIHA--PTMEEPAMPSSEEKVRKATRAALELADKECFKIVAI 111
Query 1125 PLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNL 1172
P + G+ G + + V+ +R + E+V++ +D
Sbjct 112 PGMGTGVGGVPKEVAARAMVEEIRK------FEPKCLEKVILVDIDEE 153
>sp|Q8R151|ZNFX1_MOUSE NFX1-type zinc finger-containing protein
1 OS=Mus musculus OX=10090 GN=Znfx1 PE=1 SV=3
Length=1909
Score = 84.0 bits (206), Expect = 7e-14, Method: Composition-based stats.
Identities = 54/240 (23%), Positives = 91/240 (38%), Gaps = 32/240 (13%)
Query 5671 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQL-PAPR--TLLTKGTLEPEYFNSVC 5727
IV+ +E + ++ +H + IGD QL P+ L LE F
Sbjct 995 IVIVEEAAEVLEAH-TIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFE--- 1050
Query 5728 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN--------KLKAHKDKSAQCFKMFYK- 5778
RL+K P + L R EI ++ +Y + K + K S+ F + +
Sbjct 1051 RLVKVNIPFVRLNYQHRMRPEIARLLTPHIYQDLENHPSVLKYEQIKGVSSNLFFVEHNF 1110
Query 5779 -GVITHDVSSAINRPQIGVVREF----LTRNPAWRKAVFISPYNSQNAVASKIL------ 5827
+ S N+ + V E L + + ++ Y Q K++
Sbjct 1111 PEQEIQEGKSHQNQHEAHFVVELCQYLLCQEYLPSQITILTTYTGQLFCLRKLMPVKTFA 1170
Query 5828 GLPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAITRAKIGILCIMSDRDL 5882
G+ VD QG E D ++ + Q + NR VA++RAK G+ CI + + L
Sbjct 1171 GIKVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQIPNRICVALSRAKKGMYCIGNMQML 1230
>sp|Q9P2E3|ZNFX1_HUMAN NFX1-type zinc finger-containing protein
1 OS=Homo sapiens OX=9606 GN=ZNFX1 PE=1 SV=2
Length=1918
Score = 83.6 bits (205), Expect = 7e-14, Method: Composition-based stats.
Identities = 65/295 (22%), Positives = 113/295 (38%), Gaps = 44/295 (15%)
Query 5671 IVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQL-PAPR--TLLTKGTLEPEYFNSVC 5727
IV+ +E + ++ +H + IGD QL P+ L LE F
Sbjct 1002 IVIVEEAAEVLEAH-TIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFE--- 1057
Query 5728 RLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN--------KLKAHKDKSAQCFKMFYK- 5778
RL+K P + L R EI ++ +Y + K + K S+ F + +
Sbjct 1058 RLVKVNIPFVRLNYQHRMCPEIARLLTPHIYQDLENHPSVLKYEKIKGVSSNLFFVEHNF 1117
Query 5779 -GVITHDVSSAINRPQIGVVRE----FLTRNPAWRKAVFISPYNSQNAVASKIL------ 5827
+ S N+ + V E FL + + ++ Y Q K++
Sbjct 1118 PEQEIQEGKSHQNQHEAHFVVELCKYFLCQEYLPSQITILTTYTGQLFCLRKLMPAKTFA 1177
Query 5828 GLPTQTVDSSQGSEYDYVIFT-----QTTETAHSCNVNRFNVAITRAKIGILCIMSDRDL 5882
G+ VD QG E D ++ + Q + NR VA++RAK G+ CI + + L
Sbjct 1178 GVRVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQML 1237
Query 5883 YDKLQFTSLEIPRRNVATLQAENVTG-LFKDCSKIITGLHPTQAPTHLSVDIKFK 5936
+ + + + TL+ N G + + C + HP + T +S F+
Sbjct 1238 ------AKVPLWSKIIHTLRENNQIGPMLRLCCQN----HP-ETHTLVSKASDFQ 1281
>sp|P13889|POLN_RUBVT Non-structural polyprotein p200 OS=Rubella
virus (strain Therien) OX=11045 PE=3 SV=5
Length=2116
Score = 83.6 bits (205), Expect = 8e-14, Method: Composition-based stats.
Identities = 50/233 (21%), Positives = 80/233 (34%), Gaps = 21/233 (9%)
Query 970 TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQS 1029
+ + L+ E S P+ + + Y + V ++ DI+
Sbjct 775 PAGPADRARDAELEVACEPSGPPTSTRADPDSDIVE--SYARAAGPVHLRVRDIMDPPPG 832
Query 1030 ANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA 1089
V+VNAAN L G GV GA+ A+ P G + GH
Sbjct 833 CK--VVVNAANEGLLAGSGVCGAIFANATAALAANCRRLA----PCPTGEAVATPGHGCG 886
Query 1090 -KKCLHVVGPN-----LNAGEDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPL 1137
+H V P E LL+ AY + + PLL AG++G
Sbjct 887 YTHIIHAVAPRRPRDPAALEEGEALLERAYRSIVALAAARRWACVACPLLGAGVYGWSAA 946
Query 1138 QSLQVCVQTVRTQ-VYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTED 1189
+SL+ + RT+ V ++ + + L A ++ PP TE
Sbjct 947 ESLRAALAATRTEPVERVSLHICHPDRATLTHASVLVGAGLAARRVSPPPTEP 999
>sp|Q7TZB9|Y1934_MYCBO Uncharacterized protein Mb1934c OS=Mycobacterium
bovis (strain ATCC BAA-935 / AF2122/97) OX=233413
GN=lppD PE=4 SV=1
Length=358
Score = 80.5 bits (197), Expect = 8e-14, Method: Composition-based stats.
Identities = 32/142 (23%), Positives = 55/142 (39%), Gaps = 15/142 (11%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
+ + D+ K A I NAAN L+H GGVA A+ +A +Q+ES + P
Sbjct 190 ELEVHQADVTKLELDA----ITNAANTRLRHAGGVAAAIARAGGPELQRESTE----KAP 241
Query 1075 LTVGGSCLLSGHN-LAKKCLHVVGPNLNAGEDIQLLKAAYENF------NSQDILLAPLL 1127
+ +G + + + A+ +H L +++ AA L
Sbjct 242 IGLGEAVETTAGDMPARYVIHAATMELGGPTSGEIITAATAATLRKADELGCRSLALVAF 301
Query 1128 SAGIFGAKPLQSLQVCVQTVRT 1149
G+ G + ++ V VR
Sbjct 302 GTGVGGFPLDDAARLMVGAVRR 323
>sp|P9WK29|Y1899_MYCTU Uncharacterized protein Rv1899c OS=Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv) OX=83332
GN=Rv1899c PE=1 SV=1
Length=359
Score = 80.5 bits (197), Expect = 8e-14, Method: Composition-based stats.
Identities = 32/142 (23%), Positives = 55/142 (39%), Gaps = 15/142 (11%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
+ + D+ K A I NAAN L+H GGVA A+ +A +Q+ES + P
Sbjct 191 ELEVHQADVTKLELDA----ITNAANTRLRHAGGVAAAIARAGGPELQRESTE----KAP 242
Query 1075 LTVGGSCLLSGHN-LAKKCLHVVGPNLNAGEDIQLLKAAYENF------NSQDILLAPLL 1127
+ +G + + + A+ +H L +++ AA L
Sbjct 243 IGLGEAVETTAGDMPARYVIHAATMELGGPTSGEIITAATAATLRKADELGCRSLALVAF 302
Query 1128 SAGIFGAKPLQSLQVCVQTVRT 1149
G+ G + ++ V VR
Sbjct 303 GTGVGGFPLDDAARLMVGAVRR 324
>sp|P9WK28|Y1899_MYCTO Uncharacterized protein MT1950 OS=Mycobacterium
tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=MT1950
PE=4 SV=1
Length=374
Score = 80.5 bits (197), Expect = 1e-13, Method: Composition-based stats.
Identities = 32/142 (23%), Positives = 55/142 (39%), Gaps = 15/142 (11%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGP 1074
+ + D+ K A I NAAN L+H GGVA A+ +A +Q+ES + P
Sbjct 206 ELEVHQADVTKLELDA----ITNAANTRLRHAGGVAAAIARAGGPELQRESTE----KAP 257
Query 1075 LTVGGSCLLSGHN-LAKKCLHVVGPNLNAGEDIQLLKAAYENF------NSQDILLAPLL 1127
+ +G + + + A+ +H L +++ AA L
Sbjct 258 IGLGEAVETTAGDMPARYVIHAATMELGGPTSGEIITAATAATLRKADELGCRSLALVAF 317
Query 1128 SAGIFGAKPLQSLQVCVQTVRT 1149
G+ G + ++ V VR
Sbjct 318 GTGVGGFPLDDAARLMVGAVRR 339
>sp|Q5JER1|Y1890_THEKO Uncharacterized protein TK1890 OS=Thermococcus
kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OX=69014 GN=TK1890 PE=4 SV=1
Length=180
Score = 76.3 bits (186), Expect = 1e-13, Method: Composition-based stats.
Identities = 42/179 (23%), Positives = 71/179 (40%), Gaps = 32/179 (18%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKE---SDD-YIK 1070
I DI + IVNAAN +L+HGGGVA A+ KA G ++ S + +
Sbjct 3 EFEIVKGDITR----FPAEAIVNAANRYLEHGGGVAYAIAKAAAGDPREYIRISKEAMRE 58
Query 1071 LNGP--LTVGGSCLLSGHNLAKK----CLHVVGP----NLNAGEDIQLLKAAYENFNSQD 1120
G + G + L K +H VGP + + +L KA +
Sbjct 59 QLGKDHIEHGEVVVTPAMRLEKHGIRYVIHTVGPYCGGIWDEDKKEKLRKAILGALRKAE 118
Query 1121 -----ILLAPLLSAGIFGAKPLQSLQVCVQTVR---------TQVYIAVNDKALYEQVV 1165
+ P +SAGI+G + ++ + + +VY+ + + YE+ +
Sbjct 119 ELGVKTIAFPAVSAGIYGCPLEEVVKTFKEVIDEFEREAGSVERVYLVLYSEKDYERAL 177
>sp|Q8BCR0|POLN_RUBVN Non-structural polyprotein p200 OS=Rubella
virus (strain RN-UK86) OX=376267 PE=3 SV=1
Length=2116
Score = 82.8 bits (203), Expect = 1e-13, Method: Composition-based stats.
Identities = 50/233 (21%), Positives = 83/233 (36%), Gaps = 21/233 (9%)
Query 970 TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQS 1029
+ + L+ E S + P+ + + Y + V ++ DI+
Sbjct 775 SAEPADRARHAELEVVYEPSGPPTSTKADPDSDIVE--SYARAAGPVHLRVRDIMDPPPG 832
Query 1030 ANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA 1089
V+VNAAN L G GV GA+ A+ + P G + GH
Sbjct 833 CK--VVVNAANEGLLAGSGVCGAIFANATAALAADCRRLA----PCPTGEAVATPGHGCG 886
Query 1090 -KKCLHVVGPN-----LNAGEDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPL 1137
+H V P E LL+ AY + + PLL AG++G
Sbjct 887 YTHIIHAVAPRRPRDPAALEEGEALLERAYRSIVALAAARRWACVACPLLGAGVYGWSAA 946
Query 1138 QSLQVCVQTVRTQVYIAVNDKAL-YEQVVMDYLDNLKPRVEAPKQEEPPNTED 1189
+SL+ + RT+ V+ ++ + + L A ++ PP TE
Sbjct 947 ESLRAALAATRTEPAERVSLHICHPDRATLTHASVLVGAGLAARRVSPPPTEP 999
>sp|P27283|POLN_SINDO Polyprotein P1234 OS=Sindbis virus subtype
Ockelbo (strain Edsbyn 82-5) OX=31699 PE=3 SV=2
Length=2515
Score = 82.4 bits (202), Expect = 2e-13, Method: Composition-based stats.
Identities = 55/247 (22%), Positives = 88/247 (36%), Gaps = 32/247 (13%)
Query 1032 PMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKK 1091
+VNAAN + G GV A+ K + + + G + L H KK
Sbjct 1363 EEAVVNAANPLGRPGEGVCRAIYKRWPNSFTDSATE---------TGTAKLTVCH--GKK 1411
Query 1092 CLHVVGPNLNAG---EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAK------P 1136
+H VGP+ E ++LL+ AY ++ + PLLS GI+ A
Sbjct 1412 VIHAVGPDFRKHPEAEALKLLQNAYHAVADLVNEHNIKSVAIPLLSTGIYAAGKDRLEVS 1471
Query 1137 LQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKS 1196
L L + V I DK E++ D + LK V K E+ ++
Sbjct 1472 LNCLTTALDRTDADVTIYCLDKKWKERI--DAVLQLKESVTELKDEDMEIDDELVWIHPD 1529
Query 1197 VVQKPVDVKPKIKACID---EVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMS 1253
K K + E T + K + +LF + + + + GE M
Sbjct 1530 SCLKGRKGFSTTKGKLYSYFEGTKFHQAAKDMAEIKVLFPN-DQESNEQLCAYILGETME 1588
Query 1254 FLEKDAP 1260
+ + P
Sbjct 1589 AIREKCP 1595
Score = 45.0 bits (105), Expect = 0.042, Method: Composition-based stats.
Identities = 43/193 (22%), Positives = 63/193 (33%), Gaps = 34/193 (18%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS AI + +AR + T+ + C I R
Sbjct 724 VIGTPGSGKS--AIIKSTV--TARDLVTS----------------GKKENCREIEADVLR 763
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRA-KHYVY 5699
+ ++ S V +++ DE L + A +R K V
Sbjct 764 LR---GMQITSKTVDSVMLNG---CHKAVEVLYVDEAFACHAGALLALIAIVRPRKKVVL 817
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
GDP Q + K FN R + T F+ RRC + VS L YD
Sbjct 818 CGDPKQCGFFNMMQLKVH-----FNHPERDICTKTFYKFIS--RRCTQPVTAIVSTLHYD 870
Query 5760 NKLKAHKDKSAQC 5772
K+K
Sbjct 871 GKMKTTNPCKKNI 883
>sp|P13896|POLN_WEEV Polyprotein P1234 OS=Western equine encephalitis
virus OX=11039 PE=3 SV=3
Length=2467
Score = 82.0 bits (201), Expect = 2e-13, Method: Composition-based stats.
Identities = 52/195 (27%), Positives = 72/195 (37%), Gaps = 33/195 (17%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ DI K A A IVNAAN + G GV GAL + A P+ V
Sbjct 1333 VIRGDISKSADQA----IVNAANSKGQPGSGVCGALYRKWPAAF---------DRQPIAV 1379
Query 1078 GGSCLLSGHNLAKKCLHVVGPNLNAG---EDIQLLKAAYE------NFNSQDILLAPLLS 1128
G + L+ L +H VGPN + E L AAY N + PLLS
Sbjct 1380 GTARLVKHEPL---IIHAVGPNFSKMPEPEGDLKLAAAYMSIASIVNAERITKISVPLLS 1436
Query 1129 AGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQE 1182
GI+ + L L T V I DK +++ + K VE +
Sbjct 1437 TGIYSGGKDRVMQSLHHLFTAFDTTDADVTIYCLDKQWETRIIEAI--HRKESVEILDDD 1494
Query 1183 EPPNTEDSKTEEKSV 1197
+P + + + S
Sbjct 1495 KPVDIDLVRVHPNSS 1509
Score = 48.1 bits (113), Expect = 0.004, Method: Composition-based stats.
Identities = 40/209 (19%), Positives = 67/209 (32%), Gaps = 30/209 (14%)
Query 5666 ETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNS 5725
+ + + DE L + A ++ K V GDP Q + K +
Sbjct 776 KHPVNTLYIDEAFACHAGTLLALIAIVKPKKVVLCGDPKQCGFFNMMCLKVHFNHDICTE 835
Query 5726 VCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDV 5785
V RRC + VS L YD ++K + + H
Sbjct 836 VYHK----------SISRRCTQTVTAIVSTLFYDKRMKTVNPCADKIIIDTTGTTKPHKD 885
Query 5786 SSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYV 5845
LT W K + I N + A+ GL + V + + +
Sbjct 886 ------------DLILTCFRGWVKQLQIDYKNHEIMTAAASQGLTRKGVYAVRYKVNENP 933
Query 5846 IFTQTTETAHSCNVNRFNVAITRAKIGIL 5874
+++QT+E NV +TR + I+
Sbjct 934 LYSQTSE--------HVNVLLTRTEKRIV 954
>sp|P03317|POLN_SINDV Polyprotein P1234 OS=Sindbis virus OX=11034
PE=1 SV=2
Length=2513
Score = 81.6 bits (200), Expect = 3e-13, Method: Composition-based stats.
Identities = 54/247 (22%), Positives = 87/247 (35%), Gaps = 32/247 (13%)
Query 1032 PMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKK 1091
+VNAAN + G GV A+ K + + + G + + L KK
Sbjct 1363 EEAVVNAANPLGRPGEGVCRAIYKRWPTSFTDSATE---------TGTARMTVC--LGKK 1411
Query 1092 CLHVVGPNLNAG---EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAK------P 1136
+H VGP+ E ++LL+ AY ++ + PLLS GI+ A
Sbjct 1412 VIHAVGPDFRKHPEAEALKLLQNAYHAVADLVNEHNIKSVAIPLLSTGIYAAGKDRLEVS 1471
Query 1137 LQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKS 1196
L L + V I DK E++ D LK V K E+ ++
Sbjct 1472 LNCLTTALDRTDADVTIYCLDKKWKERI--DAALQLKESVTELKDEDMEIDDELVWIHPD 1529
Query 1197 VVQKPVDVKPKIKACID---EVTTTLEETKFLTNKLLLFADINGKLYHDSQNMLRGEDMS 1253
K K + E T + K + +LF + + + + GE M
Sbjct 1530 SCLKGRKGFSTTKGKLYSYFEGTKFHQAAKDMAEIKVLFPN-DQESNEQLCAYILGETME 1588
Query 1254 FLEKDAP 1260
+ + P
Sbjct 1589 AIREKCP 1595
Score = 44.3 bits (103), Expect = 0.065, Method: Composition-based stats.
Identities = 52/254 (20%), Positives = 83/254 (33%), Gaps = 62/254 (24%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS AI + +AR + T+ + C I R
Sbjct 724 VIGTPGSGKS--AIIKSTV--TARDLVTS----------------GKKENCREIEADVLR 763
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRA-KHYVY 5699
+ ++ S V +++ DE L + A +R K V
Sbjct 764 LR---GMQITSKTVDSVMLNG---CHKAVEVLYVDEAFACHAGALLALIAIVRPRKKVVL 817
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
GDP Q + K FN + + T ++ RRC + VS L YD
Sbjct 818 CGDPMQCGFFNMMQLKVH-----FNHPEKDICTKTFYKYIS--RRCTQPVTAIVSTLHYD 870
Query 5760 NKLKAHKDKSA-------------------QCFKMFYKGVI----THDVSSA-----INR 5791
K+K CF+ + K + H+V +A + R
Sbjct 871 GKMKTTNPCKKNIEIDITGATKPKPGDIILTCFRGWVKQLQIDYPGHEVMTAAASQGLTR 930
Query 5792 PQIGVVREFLTRNP 5805
+ VR+ + NP
Sbjct 931 KGVYAVRQKVNENP 944
>sp|Q4QXJ8|POLN_EEEVF Polyprotein P1234 OS=Eastern equine encephalitis
virus (strain Florida 91-469) OX=374598 PE=1 SV=3
Length=2494
Score = 81.6 bits (200), Expect = 3e-13, Method: Composition-based stats.
Identities = 61/264 (23%), Positives = 91/264 (34%), Gaps = 43/264 (16%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ DI K N VIVNAAN + G GV GAL + GA K P+
Sbjct 1333 VVRGDITKS----NDEVIVNAANNKGQPGSGVCGALYRKWPGAFDK---------QPVAT 1379
Query 1078 GGSCLLSGHNLAKKCLHVVGP---NLNAGEDIQLLKAAYE------NFNSQDILLAPLLS 1128
G + L+ + +H VGP L+ E Q L Y N + PLLS
Sbjct 1380 GKAHLV---KHSPNVIHAVGPNFSRLSENEGDQKLSEVYMDIARIINNERFTKVSIPLLS 1436
Query 1129 AGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQE 1182
GI+ + L L + T + I DK ++ K VE ++
Sbjct 1437 TGIYAGGKDRVMQSLNHLFTAMDTTDADITIYCLDKQWESRIKEAIT--RKESVEELTED 1494
Query 1183 EPPNTEDSKTEEKSVVQKPVDVKPKIKACIDEVTTTLEETKFLTNKLLLFADI------N 1236
+ P + + +P +V + LE T+F A+I
Sbjct 1495 DRPV---DIELVRVHPLSSLAGRPGYSTTEGKVYSYLEGTRF-HQTAKDIAEIYAMWPNK 1550
Query 1237 GKLYHDSQNMLRGEDMSFLEKDAP 1260
+ + GE M+ + P
Sbjct 1551 QEANEQICLYVLGESMNSIRSKCP 1574
Score = 55.1 bits (131), Expect = 3e-05, Method: Composition-based stats.
Identities = 56/294 (19%), Positives = 96/294 (33%), Gaps = 56/294 (19%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS G+ + R + + + C II R
Sbjct 717 VYGVPGSGKS----GIIKSAVTKRDLVVSA----------------KKENCMEIIKDVKR 756
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
+ D +N + + + D + DE L + A ++ K V
Sbjct 757 MRGMDI-----AARTVDSVLLNGV-KHSVDTLYIDEAFACHAGTLLALIAIVKPKKVVLC 810
Query 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
GDP Q + K E V RRC + VS L YD
Sbjct 811 GDPKQCGFFNMMCLKVHFNHEICTEVYHK----------SISRRCTKTVTSIVSTLFYDK 860
Query 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
+++ + + D +S + ++ LT W K + I N +
Sbjct 861 RMRTVNPCNDKII---------IDTTSTTKPLKDDII---LTCFRGWVKQLQIDYKNHEI 908
Query 5821 AVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGIL 5874
A+ GL + V + + + ++ QT+E NV +TR + I+
Sbjct 909 MTAAASQGLTRKGVYAVRYKVNENPLYAQTSE--------HVNVLLTRTEKRIV 954
>sp|Q02874|H2AY_RAT Core histone macro-H2A.1 OS=Rattus norvegicus
OX=10116 GN=Macroh2a1 PE=1 SV=5
Length=368
Score = 78.6 bits (192), Expect = 4e-13, Method: Composition-based stats.
Identities = 38/199 (19%), Positives = 70/199 (35%), Gaps = 12/199 (6%)
Query 985 TTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAI---KCVDIVKEAQSANPMVIVNAANI 1041
+ +Q E+ G+ L+ K + + S + +V+ N
Sbjct 158 SKKQGEVSKAASADSTTEGAPTDGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNA 217
Query 1042 HLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGPNL 1100
GG V L K + + K NGPL V G+ + +GH L AK +H P
Sbjct 218 DFYIGGEVGSTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVW 277
Query 1101 NAGEDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIA 1154
A + +LL+ +N + P + +G G + Q+ ++ + + Y
Sbjct 278 GADKCEELLEKTVKNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLILKAISS--YFV 335
Query 1155 VNDKALYEQVVMDYLDNLK 1173
+ + V D+
Sbjct 336 STMSSSIKTVYFVLFDSES 354
>sp|Q9QZQ8|H2AY_MOUSE Core histone macro-H2A.1 OS=Mus musculus
OX=10090 GN=Macroh2a1 PE=1 SV=4
Length=369
Score = 78.2 bits (191), Expect = 6e-13, Method: Composition-based stats.
Identities = 38/196 (19%), Positives = 68/196 (35%), Gaps = 12/196 (6%)
Query 988 QSEIEPEPEPTPEEPVNQFTGYLKLTDNVAI---KCVDIVKEAQSANPMVIVNAANIHLK 1044
Q E+ G+ L+ K + + S + +V+ N
Sbjct 162 QGEVSKAASADSTTEGTPTDGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNTDFY 221
Query 1045 HGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAG 1103
GG V L K + + K NGPL V G+ + +GH L AK +H P A
Sbjct 222 TGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAISAGHGLPAKFVIHCNSPVWGAD 281
Query 1104 EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVND 1157
+ +LL+ +N + P + +G G + Q+ ++ + + Y
Sbjct 282 KCEELLEKTVKNCLALADDRKLKSIAFPSIGSGRNGFPKQTAAQLILKAISS--YFVSTM 339
Query 1158 KALYEQVVMDYLDNLK 1173
+ + V D+
Sbjct 340 SSSIKTVYFMLFDSES 355
>sp|Q8NYB7|ADPRH_STAAW Protein-ADP-ribose hydrolase OS=Staphylococcus
aureus (strain MW2) OX=196620 GN=MW0302 PE=3 SV=1
Length=266
Score = 76.3 bits (186), Expect = 7e-13, Method: Composition-based stats.
Identities = 34/154 (22%), Positives = 64/154 (42%), Gaps = 23/154 (15%)
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLK------HGGGVAGALNKATNGAMQKESDD 1067
DN+ + DI + IVNAAN H + ++ ++ + +
Sbjct 85 DNIFVWQGDIT----TLKIDAIVNAANSRFLGCMQANHDC-IDNIIHTKAGVQVRLDCAE 139
Query 1068 YIKLNGPLT-VGGSCLLSGHNL-AKKCLHVVGPNLN----AGEDIQLLKAAYENF----- 1116
I+ G VG + + G+NL AK +H VGP + + + LL Y +
Sbjct 140 IIRQQGRNEGVGKAKITRGYNLPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLAD 199
Query 1117 -NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
+S + + +S G+F ++ ++ V+TV +
Sbjct 200 QHSLNHVAFCCISTGVFAFPQDEAAEIAVRTVES 233
>sp|Q6GCE6|ADPRH_STAAS Protein-ADP-ribose hydrolase OS=Staphylococcus
aureus (strain MSSA476) OX=282459 GN=SAS0302 PE=3 SV=1
Length=266
Score = 76.3 bits (186), Expect = 7e-13, Method: Composition-based stats.
Identities = 34/154 (22%), Positives = 64/154 (42%), Gaps = 23/154 (15%)
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLK------HGGGVAGALNKATNGAMQKESDD 1067
DN+ + DI + IVNAAN H + ++ ++ + +
Sbjct 85 DNIFVWQGDIT----TLKIDAIVNAANSRFLGCMQANHDC-IDNIIHTKAGVQVRLDCAE 139
Query 1068 YIKLNGPLT-VGGSCLLSGHNL-AKKCLHVVGPNLN----AGEDIQLLKAAYENF----- 1116
I+ G VG + + G+NL AK +H VGP + + + LL Y +
Sbjct 140 IIRQQGRNEGVGKAKITRGYNLPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLAD 199
Query 1117 -NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
+S + + +S G+F ++ ++ V+TV +
Sbjct 200 QHSLNHVAFCCISTGVFAFPQDEAAEIAVRTVES 233
>sp|Q5HIW9|ADPRH_STAAC Protein-ADP-ribose hydrolase OS=Staphylococcus
aureus (strain COL) OX=93062 GN=SACOL0396 PE=3 SV=1
Length=266
Score = 76.3 bits (186), Expect = 8e-13, Method: Composition-based stats.
Identities = 34/154 (22%), Positives = 64/154 (42%), Gaps = 23/154 (15%)
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLK------HGGGVAGALNKATNGAMQKESDD 1067
DN+ + DI + IVNAAN H + ++ ++ + +
Sbjct 85 DNIFVWQGDIT----TLKIDAIVNAANSRFLGCMQANHDC-IDNIIHTKAGVQVRLDCAE 139
Query 1068 YIKLNGPLT-VGGSCLLSGHNL-AKKCLHVVGPNLN----AGEDIQLLKAAYENF----- 1116
I+ G VG + + G+NL AK +H VGP + + + LL Y +
Sbjct 140 IIRQQGRNEGVGKAKITRGYNLSAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLAD 199
Query 1117 -NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
+S + + +S G+F ++ ++ V+TV +
Sbjct 200 QHSLNHVAFCCISTGVFAFPQDEAAEIAVRTVES 233
>sp|Q6X2U2|POLN_RUBVC Non-structural polyprotein p200 OS=Rubella
virus (strain BRDII) OX=376263 PE=3 SV=1
Length=2116
Score = 80.1 bits (196), Expect = 9e-13, Method: Composition-based stats.
Identities = 30/112 (27%), Positives = 44/112 (39%), Gaps = 16/112 (14%)
Query 1034 VIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA-KKC 1092
V+VNAAN L G GV GA+ + ++ ++ P G + GH
Sbjct 835 VVVNAANEGLLAGSGVCGAIFASAAASLAEDCRRLA----PCPTGEAVATPGHGCGYAHI 890
Query 1093 LHVVGPN-----LNAGEDIQLLKAAYENF------NSQDILLAPLLSAGIFG 1133
+H V P + LL+ AY + + PLL AGI+G
Sbjct 891 IHAVAPRRPQDPAALEQSEALLERAYRSIVALAAARRWTCVACPLLGAGIYG 942
>sp|O75367|H2AY_HUMAN Core histone macro-H2A.1 OS=Homo sapiens
OX=9606 GN=MACROH2A1 PE=1 SV=5
Length=369
Score = 77.4 bits (189), Expect = 9e-13, Method: Composition-based stats.
Identities = 38/196 (19%), Positives = 68/196 (35%), Gaps = 12/196 (6%)
Query 988 QSEIEPEPEPTPEEPVNQFTGYLKLTDNVAI---KCVDIVKEAQSANPMVIVNAANIHLK 1044
Q E+ G+ L+ K + + S + +V+ N
Sbjct 162 QGEVSKAASADSTTEGTPADGFTVLSTKSLFLGQKLQVVQADIASIDSDAVVHPTNTDFY 221
Query 1045 HGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAG 1103
GG V L K + + K NGPL V G+ + +GH L AK +H P A
Sbjct 222 IGGEVGNTLEKKGGKEFVEAVLELRKKNGPLEVAGAAVSAGHGLPAKFVIHCNSPVWGAD 281
Query 1104 EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVND 1157
+ +LL+ +N + P + +G G + Q+ ++ + + Y
Sbjct 282 KCEELLEKTVKNCLALADDKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISS--YFVSTM 339
Query 1158 KALYEQVVMDYLDNLK 1173
+ + V D+
Sbjct 340 SSSIKTVYFVLFDSES 355
>sp|Q86924|POLN_AURAV Polyprotein P1234 OS=Aura virus OX=44158
PE=3 SV=3
Length=2499
Score = 80.1 bits (196), Expect = 1e-12, Method: Composition-based stats.
Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 26/149 (17%)
Query 1031 NPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAK 1090
+VNAAN K G GV A+ K + + + + V + + HN K
Sbjct 1360 TEEAVVNAANARGKPGDGVCRAIFKKWPKSFENATTE---------VETAVMKPCHN--K 1408
Query 1091 KCLHVVGPNLNAG---EDIQLLKAAY----ENFNSQDI--LLAPLLSAGIFGAK------ 1135
+H VGP+ E +LL+ AY + N + I + PLLS GI+ A
Sbjct 1409 VVIHAVGPDFRKYTLEEATKLLQNAYHDVAKIVNEKGISSVAIPLLSTGIYAAGADRLDL 1468
Query 1136 PLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
L+ L + V I DK +++
Sbjct 1469 SLRCLFTALDRTDADVTIYCLDKKWEQRI 1497
Score = 49.7 bits (117), Expect = 0.002, Method: Composition-based stats.
Identities = 49/254 (19%), Positives = 83/254 (33%), Gaps = 62/254 (24%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS AI + + + + T+ + K + +R + +
Sbjct 723 VIGTPGSGKS--AIIKSTV--TLKDLVTSGKKENCKEIENDVQKMRGMTIATRTVDSVL- 777
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5699
+ +K D++ DE L + A ++ + V
Sbjct 778 ---LNGWK------------------KAVDVLYVDEAFACHAGTLMALIAIVKPRRKVVL 816
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
GDP Q P + K FN+ R + T ++ RRC + VS L YD
Sbjct 817 CGDPKQWPFFNLMQLKV-----NFNNPERDLCTSTHYKYIS--RRCTQPVTAIVSTLHYD 869
Query 5760 NKLKAHKDKSA-------------------QCFKMFYK-------GVITHD--VSSAINR 5791
K++ CF+ + K G HD S + R
Sbjct 870 GKMRTTNPCKRAIEIDVNGSTKPKKGDIVLTCFRGWVKQGQIDYPGPGGHDRAASQGLTR 929
Query 5792 PQIGVVREFLTRNP 5805
+ VR+ + NP
Sbjct 930 RGVYAVRQKVNENP 943
>sp|Q8B912|RPOA_PRRSB Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain HB-1) OX=300563
GN=rep PE=2 SV=3
Length=3961
Score = 80.1 bits (196), Expect = 1e-12, Method: Composition-based stats.
Identities = 95/560 (17%), Positives = 180/560 (32%), Gaps = 110/560 (20%)
Query 4814 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA-NQVIVNNLDKSAG 4872
+AA+ D Y L V+ +V KY + G C + AG
Sbjct 2738 CEDAALRDLSKYDLVTQGFV----LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAG 2793
Query 4873 FPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSIC 4932
N++ + S + D L A R T+T LK K + RT+ G +
Sbjct 2794 INGNRFPTKDI----QSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNF 2849
Query 4933 STMTNRQFHQKLLKSIAATR-GATVVIGTSKFYGGWHNMLKTVYSDVETPHL---MGWDY 4988
+ +R + + + + +G +KF +++TP L + D
Sbjct 2850 IALAHRAALSGVTQGFMKKAFNSPIALGKNKF------------KELQTPVLGRCLEADL 2897
Query 4989 PKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGG 5048
CDR+ P ++R A+ +L C H + N C ++++ K GG
Sbjct 2898 ASCDRSTPAIVRWFAANLLYEL---ACAEEHLPSYVLNCCH----DLLVTQSGAVTKRGG 2950
Query 5049 TSSGDATTAYANSVFN---ICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRD 5105
SSGD T+ +N++++ Q + + G+ ++++
Sbjct 2951 LSSGDPITSVSNTIYSLVIYAQHMVLSYFK----SGHPHGLLFLQDQLK----------- 2995
Query 5106 VDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSE 5165
+ + K +++ SDD +V Y + + +++ +L +Q
Sbjct 2996 ---------FEDMLKVQPLIVYSDD-LVLYAESPSMPNYHWWVEHLNLMLGFQT----DP 3041
Query 5166 AKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMI 5225
K T F + G V P+ RIL A +
Sbjct 3042 KKTAITDSPT-----FLG---CRIINGRQLV----PNRDRILAALAYHMKASNVSEYYAS 3089
Query 5226 ERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYW 5285
++ +D+ ++ + + ++ Q RK D YS +
Sbjct 3090 A--AAILMDSCACLEYDPEWFEELVVGIAQCARK----------DGYS----------FP 3127
Query 5286 EPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYD----HVISTSHK 5341
P F+ +M+ + S CG C+ C D H H
Sbjct 3128 GPPFFLSMWEKLRSNHE--------GKKSRMCGYCMAPAPYATACGLDVCVYHTHFHQHC 3179
Query 5342 LVLSVNPYVCNAPGCDVTDV 5361
V+ + + C +
Sbjct 3180 PVIIWCGHPAGSGSCGECEP 3199
Score = 65.1 bits (157), Expect = 3e-08, Method: Composition-based stats.
Identities = 51/251 (20%), Positives = 92/251 (37%), Gaps = 52/251 (21%)
Query 6565 NARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESV------KTQFNYFKKVDGIIQQL 6618
+N + V L P ++A + ++G SV + K V G Q L
Sbjct 3624 TTQNNERWPDRLVASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVRGEAQVL 3683
Query 6619 PETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLE-GYAFEHIVYGDFSHGQLGGL 6677
PET F+ R +E+ E++ + E + H GD +GG
Sbjct 3684 PETVFSTGR---------------IEVDCREYLDDREREVAESLPHAFIGDVKGTTVGGC 3728
Query 6678 HLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTG-SSKCVCSVIDLLLDDFVEIIK 6736
H + L F+P +S + + G ++K C++ D+ L D +
Sbjct 3729 HHVTSKY---------LPRFLPKESVA---VVGVSSPGEAAKAFCTLTDVYLPDLEAYLH 3776
Query 6737 SQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQAS-------QAWQPGVAMPNL 6789
+ SK KV +D+ E+ M+W +T Y +L+ ++ + +P
Sbjct 3777 PE---TQSKCWKVMLDFKEVRLMVW----KGKTAYFQLEGRHFTWYQLASYTSYIRVPV- 3828
Query 6790 YKMQRMLLEKC 6800
+ L+ C
Sbjct 3829 --NSTVYLDPC 3837
Score = 64.3 bits (155), Expect = 6e-08, Method: Composition-based stats.
Identities = 76/408 (19%), Positives = 132/408 (32%), Gaps = 92/408 (23%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALK-YLPIDKCSRII 5635
+ + GPPG GK+H+ + ++YT +H + + + + +
Sbjct 3287 RSRFIIGPPGAGKTHWLLQQV---QDGDVIYT-PTHQTMLDMIRALGTCRFNVPAGTTL- 3341
Query 5636 PARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK 5695
+F S +V + DE + + D+ + ++
Sbjct 3342 ----------QFPAPSRTGPWVRILAGGWCPGKNSFL--DEAAYCNHLDVLRLLSKTT-- 3387
Query 5696 HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSA 5755
+GD QL P F+S C + I P L T R I D +
Sbjct 3388 -LTCLGDFKQL------------HPVGFDSHCYVF-DIMPQTQLKTIWRFGQNICDAIQP 3433
Query 5756 LVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISP 5815
Y +KL S +N ++ V + R ++P
Sbjct 3434 D-YRDKLV-----------------------SMVNTTRVTYVEK------PVRYGQVLTP 3463
Query 5816 YNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILC 5875
Y+ + T+DSSQG+ +D V T T S N R VAITRA+ I
Sbjct 3464 YHRDREDGA-------ITIDSSQGATFDVV--TLHLPTKDSLNRQRALVAITRARHAIFV 3514
Query 5876 IMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKF 5935
R L + N+A + E + L + + QA L KF
Sbjct 3515 YDPHRQLQSMFDL-PAKGTPVNLAVHRDEQLIVL----DRNNKEITVAQA---LGNGDKF 3566
Query 5936 KTEG---------LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
+ +C D+ G + ++ +GF + + + +
Sbjct 3567 RATDKRVVDSLRAICADLEGSSSPLP--KVAHNLGFYFSPDLTQFAKL 3612
>sp|O40955|POLN_RUBVR Non-structural polyprotein p200 OS=Rubella
virus (strain RA27/3 vaccine) OX=11044 PE=1 SV=1
Length=2116
Score = 79.7 bits (195), Expect = 1e-12, Method: Composition-based stats.
Identities = 50/233 (21%), Positives = 84/233 (36%), Gaps = 21/233 (9%)
Query 970 TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQS 1029
+ + + L+ E S + P+ + + Y + V ++ DI+
Sbjct 775 SAGPADRARDAELEVAYEPSGPPTSTKADPDSDIVE--SYARAAGPVHLRVRDIMDPPPG 832
Query 1030 ANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA 1089
V+VNAAN L G GV GA+ A+ + P G + GH
Sbjct 833 CK--VVVNAANEGLLAGSGVCGAIFANATAALAADCRRLA----PCPTGEAVATPGHGCG 886
Query 1090 -KKCLHVVGPN-----LNAGEDIQLLKAAYENFNSQDILLA------PLLSAGIFGAKPL 1137
+H V P E LL+ AY + + PLL AG++G
Sbjct 887 YTHIIHAVAPRRPRDPAALEEGEALLERAYRSIVALAAARRWARVACPLLGAGVYGWSAA 946
Query 1138 QSLQVCVQTVRTQVYIAVNDKAL-YEQVVMDYLDNLKPRVEAPKQEEPPNTED 1189
+SL+ + RT+ V+ ++ + + L A ++ PP TE
Sbjct 947 ESLRAALAATRTEPAERVSLHICHPDRATLTHASVLVGAGLAARRVSPPPTEP 999
>sp|A7T167|GDAP2_NEMVE Protein GDAP2 homolog OS=Nematostella vectensis
OX=45351 GN=gdap2 PE=3 SV=1
Length=502
Score = 78.6 bits (192), Expect = 1e-12, Method: Composition-based stats.
Identities = 41/238 (17%), Positives = 76/238 (32%), Gaps = 22/238 (9%)
Query 978 EEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVN 1037
T + E ++ F ++ V + DI K A IVN
Sbjct 15 SLPKWSTTPVPNYEPGSNESQSSSFLSPFPVDEEINAKVVLWNGDITKLA----ADAIVN 70
Query 1038 AANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVV 1096
N L G ++ +++A + +E + G + + G+NL A+ +H V
Sbjct 71 TTNESLSDRGALSERVHRAAGPELMQECRQQLL---GCRTGEAKISEGYNLPARYVIHTV 127
Query 1097 GPNLN---AGEDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCVQTV 1147
GP N L + Y N N + +++ G P + ++TV
Sbjct 128 GPRYNTKYKTAAESALFSCYRNTMRLVRENKISTIGVCVVNTTKRGYPPEDGAHIALRTV 187
Query 1148 RTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVK 1205
R + + + ++ V K D E ++ P D+
Sbjct 188 RRFLEKYGS-----AVDTVAFVVEGAEAVVYAKVMPIYFPRDKLEEAHALTLMPDDIG 240
>sp|Q6X2U4|POLN_RUBVB Non-structural polyprotein p200 OS=Rubella
virus (strain BRD1) OX=376262 PE=3 SV=1
Length=2116
Score = 79.7 bits (195), Expect = 1e-12, Method: Composition-based stats.
Identities = 40/189 (21%), Positives = 63/189 (33%), Gaps = 26/189 (14%)
Query 958 QGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKL-TDNV 1016
G P ++ R + E E + + +P+ E + G + L N+
Sbjct 767 AGDPASPISAEPADRARDAEPEVACEPGGPATPTRADPDSDIVESYARAAGPVHLRVRNI 826
Query 1017 AIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLT 1076
V+VNAAN L G GV GA+ + + ++ P
Sbjct 827 MDPP---------PGCKVVVNAANEGLLAGSGVCGAIFASAAATLAEDCRRLA----PCP 873
Query 1077 VGGSCLLSGHNLA-KKCLHVVGPN-----LNAGEDIQLLKAAYENF------NSQDILLA 1124
G + GH +H V P + LL+ AY + +
Sbjct 874 TGEAVATPGHGCGYTHIIHAVAPRRPQDPAALEQSEALLERAYRSVVALAAARRWACVAC 933
Query 1125 PLLSAGIFG 1133
PLL AGI+G
Sbjct 934 PLLGAGIYG 942
>sp|Q5XXP4|POLN_CHIK3 Polyprotein P1234 OS=Chikungunya virus (strain
37997) OX=371095 PE=1 SV=1
Length=2474
Score = 79.3 bits (194), Expect = 1e-12, Method: Composition-based stats.
Identities = 40/168 (24%), Positives = 62/168 (37%), Gaps = 30/168 (18%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ +K +DI K + +VNAAN G GV A+ K ES
Sbjct 1333 CAPSYRVKRMDIAKN----DEECVVNAANPRGLPGDGVCKAVYKK-----WPESF----K 1379
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGP---NLNAGEDIQLLKAAYENFNSQ------DIL 1122
N VG + + +H VGP N + E + L AAY + + +
Sbjct 1380 NSATPVGTAKTVMCGTYP--VIHAVGPNFSNYSESEGDRELAAAYREVAKEVTRLGVNSV 1437
Query 1123 LAPLLSAGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
PLLS G++ + L L + + V I DK +++
Sbjct 1438 AIPLLSTGVYSGGKDRLTQSLNHLFTALDSTDADVVIYCRDKEWEKKI 1485
Score = 42.7 bits (99), Expect = 0.19, Method: Composition-based stats.
Identities = 42/254 (17%), Positives = 77/254 (30%), Gaps = 65/254 (26%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS L + T+ + ++ ++ +R + +
Sbjct 719 VFGVPGSGKSAIIKNLVTRQD----LVTSGKKENCQEISTDVMRQRNLEISARTVDSLLL 774
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5699
C D++ DE + L + A +R + V
Sbjct 775 NGCN----------------------RPVDVLYVDEAFACHSGTLLALIALVRPRQKVVL 812
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
GDP Q + K V RRC + VS+L Y+
Sbjct 813 CGDPKQCGFFNMMQMK----------VNYNHNICTQVYHKSISRRCTLPVTAIVSSLHYE 862
Query 5760 NKLKAHKDKSA-------------------QCFKMFYKGVI----THDVSSA-----INR 5791
K++ + + CF+ + K + H+V +A + R
Sbjct 863 GKMRTTNEYNKPIVVDTTGSTKPDPGDLVLTCFRGWVKQLQIDYRGHEVMTAAASQGLTR 922
Query 5792 PQIGVVREFLTRNP 5805
+ VR+ + NP
Sbjct 923 KGVYAVRQKVNENP 936
>sp|Q8P0X2|ADPRH_STRP8 Protein-ADP-ribose hydrolase OS=Streptococcus
pyogenes serotype M18 (strain MGAS8232) OX=186103 GN=spyM18_1168
PE=3 SV=1
Length=270
Score = 75.5 bits (184), Expect = 1e-12, Method: Composition-based stats.
Identities = 31/133 (23%), Positives = 51/133 (38%), Gaps = 18/133 (14%)
Query 1033 MVIVNAANIHLKH-----GGGVAGALNKATNGAMQKESDDYIKLNG-PLTVGGSCLLSGH 1086
IVNAAN L G + A++ ++ + G +G + L S +
Sbjct 99 DAIVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAY 158
Query 1087 NL-AKKCLHVVGPNLNAGEDIQ-----LLKAAYENFN------SQDILLAPLLSAGIFGA 1134
+L A +H VGP + G + LL Y + L +S G FG
Sbjct 159 HLPASYIIHTVGPRITKGRHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF 218
Query 1135 KPLQSLQVCVQTV 1147
++ Q+ ++TV
Sbjct 219 PKKEAAQIAIKTV 231
>sp|Q5XC09|ADPRH_STRP6 Protein-ADP-ribose hydrolase OS=Streptococcus
pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)
OX=286636 GN=M6_Spy0919 PE=3 SV=1
Length=270
Score = 75.1 bits (183), Expect = 2e-12, Method: Composition-based stats.
Identities = 31/133 (23%), Positives = 51/133 (38%), Gaps = 18/133 (14%)
Query 1033 MVIVNAANIHLKH-----GGGVAGALNKATNGAMQKESDDYIKLNG-PLTVGGSCLLSGH 1086
IVNAAN L G + A++ ++ + G +G + L S +
Sbjct 99 DAIVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAY 158
Query 1087 NL-AKKCLHVVGPNLNAGEDIQ-----LLKAAYENFN------SQDILLAPLLSAGIFGA 1134
+L A +H VGP + G + LL Y + L +S G FG
Sbjct 159 HLPASYIIHTVGPRITKGRHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF 218
Query 1135 KPLQSLQVCVQTV 1147
++ Q+ ++TV
Sbjct 219 PKKEAAQIAIKTV 231
>sp|O93327|H2AY_CHICK Core histone macro-H2A.1 OS=Gallus gallus
OX=9031 GN=MACROH2A1 PE=1 SV=4
Length=369
Score = 77.0 bits (188), Expect = 2e-12, Method: Composition-based stats.
Identities = 35/196 (18%), Positives = 68/196 (35%), Gaps = 12/196 (6%)
Query 988 QSEIEPEPEPTPEEPVNQFTGYLKLTDNVAI---KCVDIVKEAQSANPMVIVNAANIHLK 1044
Q E+ G+ L+ K + + + + +V+ N
Sbjct 162 QGEVSKSASADSTTEGTPADGFTVLSTKSLFLGQKLQVVQADIATIDSDAVVHPTNSDFY 221
Query 1045 HGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAG 1103
GG V L K + + K NGPL + G+ + +GH L AK +H P +
Sbjct 222 TGGEVGSTLEKKGGKEFVEAVIELRKKNGPLDIAGAVVSAGHGLPAKFVIHCNSPGWGSD 281
Query 1104 EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVND 1157
+ +LL+ +N + P + +G G + Q+ ++ + + Y
Sbjct 282 KCEELLEKTVKNCLALADEKKLKSIAFPSIGSGRNGFPKQTAAQLILKAISS--YFVSTM 339
Query 1158 KALYEQVVMDYLDNLK 1173
+ + V D+
Sbjct 340 SSSIKTVYFVLFDSES 355
>sp|P0DN70|ADPRH_STRPG Protein-ADP-ribose hydrolase OS=Streptococcus
pyogenes serotype M5 (strain Manfredo) OX=160491 GN=SpyM50868
PE=1 SV=1
Length=270
Score = 75.1 bits (183), Expect = 2e-12, Method: Composition-based stats.
Identities = 31/133 (23%), Positives = 51/133 (38%), Gaps = 18/133 (14%)
Query 1033 MVIVNAANIHLKH-----GGGVAGALNKATNGAMQKESDDYIKLNG-PLTVGGSCLLSGH 1086
IVNAAN L G + A++ ++ + G +G + L S +
Sbjct 99 DAIVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAY 158
Query 1087 NL-AKKCLHVVGPNLNAGEDIQ-----LLKAAYENFN------SQDILLAPLLSAGIFGA 1134
+L A +H VGP + G + LL Y + L +S G FG
Sbjct 159 HLPASYIIHTVGPRITKGRHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF 218
Query 1135 KPLQSLQVCVQTV 1147
++ Q+ ++TV
Sbjct 219 PKKEAAQIAIKTV 231
>sp|P0DC29|ADPRH_STRPQ Protein-ADP-ribose hydrolase OS=Streptococcus
pyogenes serotype M3 (strain SSI-1) OX=193567 GN=SPs1056
PE=3 SV=1
Length=270
Score = 75.1 bits (183), Expect = 2e-12, Method: Composition-based stats.
Identities = 31/133 (23%), Positives = 51/133 (38%), Gaps = 18/133 (14%)
Query 1033 MVIVNAANIHLKH-----GGGVAGALNKATNGAMQKESDDYIKLNG-PLTVGGSCLLSGH 1086
IVNAAN L G + A++ ++ + G +G + L S +
Sbjct 99 DAIVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAY 158
Query 1087 NL-AKKCLHVVGPNLNAGEDIQ-----LLKAAYENFN------SQDILLAPLLSAGIFGA 1134
+L A +H VGP + G + LL Y + L +S G FG
Sbjct 159 HLPASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF 218
Query 1135 KPLQSLQVCVQTV 1147
++ Q+ ++TV
Sbjct 219 PKKEAAQIAIKTV 231
>sp|P0DC28|ADPRH_STRP3 Protein-ADP-ribose hydrolase OS=Streptococcus
pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315)
OX=198466 GN=SpyM3_0856 PE=3 SV=1
Length=270
Score = 75.1 bits (183), Expect = 2e-12, Method: Composition-based stats.
Identities = 31/133 (23%), Positives = 51/133 (38%), Gaps = 18/133 (14%)
Query 1033 MVIVNAANIHLKH-----GGGVAGALNKATNGAMQKESDDYIKLNG-PLTVGGSCLLSGH 1086
IVNAAN L G + A++ ++ + G +G + L S +
Sbjct 99 DAIVNAANSELLGCFIPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAY 158
Query 1087 NL-AKKCLHVVGPNLNAGEDIQ-----LLKAAYENFN------SQDILLAPLLSAGIFGA 1134
+L A +H VGP + G + LL Y + L +S G FG
Sbjct 159 HLPASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF 218
Query 1135 KPLQSLQVCVQTV 1147
++ Q+ ++TV
Sbjct 219 PKKEAAQIAIKTV 231
>sp|A6YQT5|RPOA_PRRSV Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus OX=28344 PE=1 SV=2
Length=3931
Score = 78.9 bits (193), Expect = 2e-12, Method: Composition-based stats.
Identities = 96/560 (17%), Positives = 182/560 (33%), Gaps = 110/560 (20%)
Query 4814 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA-NQVIVNNLDKSAG 4872
+AA+ D Y + L V+ +V KY + G C + AG
Sbjct 2708 CEDAALRDLSKYDLSTQGFV----LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAG 2763
Query 4873 FPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSIC 4932
N++ + S + D L A R T+T LK K + RT+ G +
Sbjct 2764 INGNRFPTKDI----QSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNF 2819
Query 4933 STMTNRQFHQKLLKSIAATR-GATVVIGTSKFYGGWHNMLKTVYSDVETPHL---MGWDY 4988
+ +R + + + + +G +KF +++ P L + D
Sbjct 2820 IALAHRAALSGVTQGFMKKAFNSPIALGKNKF------------KELQAPVLGRCLEADL 2867
Query 4989 PKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGG 5048
CDR+ P ++R A+ +L C H + N C ++++ K GG
Sbjct 2868 ASCDRSTPAIVRWFAANLLYEL---ACAEEHLPSYVLNCCH----DLLVTQSGAVTKRGG 2920
Query 5049 TSSGDATTAYANSVFN---ICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRD 5105
SSGD T+ +N++++ Q + + G+ ++++
Sbjct 2921 LSSGDPITSVSNTIYSLVIYAQHMVLSYFK----SGHPHGLLFLQDQLK----------- 2965
Query 5106 VDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSE 5165
+ + K +++ SDD +V Y + + +++ +L +Q
Sbjct 2966 ---------FEDMLKVQPLIVYSDD-LVLYAESPSMPNYHWWVEHLNLMLGFQT----DP 3011
Query 5166 AKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMI 5225
K T +T P S + G V P+ RIL A +
Sbjct 3012 KK----TTITDSP----SFLGCRIINGRQLV----PNRDRILAALAYHMKASNVSEYYAS 3059
Query 5226 ERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYW 5285
++ +D+ ++ + + ++ Q RK D YS +
Sbjct 3060 A--AAILMDSCACLEYDPEWFEELVVGIAQCARK----------DGYS----------FP 3097
Query 5286 EPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYD----HVISTSHK 5341
P F+ +M+ + S CG C C D H H
Sbjct 3098 GPPFFLSMWEKLRSNHE--------GKKSRMCGYCGAPAPYATACGLDVCVYHTHFHQHC 3149
Query 5342 LVLSVNPYVCNAPGCDVTDV 5361
V+ + + C +
Sbjct 3150 PVIIWCGHPAGSGSCSECEP 3169
Score = 65.5 bits (158), Expect = 3e-08, Method: Composition-based stats.
Identities = 52/250 (21%), Positives = 93/250 (37%), Gaps = 50/250 (20%)
Query 6565 NARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESV------KTQFNYFKKVDGIIQQL 6618
+N + V L P ++A + ++G SV + K V G Q L
Sbjct 3594 TTQNNERWPDRLVASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVRGEAQVL 3653
Query 6619 PETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLE-GYAFEHIVYGDFSHGQLGGL 6677
PET F+ R +E+ E++ + E + H GD +GG
Sbjct 3654 PETVFSTGR---------------IEVDCREYLDDREREVAESLPHAFIGDVKGTTVGGC 3698
Query 6678 HLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKS 6737
H + L F+P +S + ++K VC++ D+ L D +
Sbjct 3699 HHVTSKY---------LPRFLPKESV--AVVGVSSPGKAAKAVCTLTDVYLPDLEAYLHP 3747
Query 6738 QDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQAS-------QAWQPGVAMPNLY 6790
+ S+ KV +D+ E+ M+W KD +T Y +L+ ++ + +P
Sbjct 3748 E---TQSRCWKVMLDFKEVRLMVW-KD---KTAYFQLEGRHFTWYQLASYASYIRVPV-- 3798
Query 6791 KMQRMLLEKC 6800
+ L+ C
Sbjct 3799 -NSTVYLDPC 3807
Score = 63.9 bits (154), Expect = 7e-08, Method: Composition-based stats.
Identities = 76/408 (19%), Positives = 132/408 (32%), Gaps = 92/408 (23%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALK-YLPIDKCSRII 5635
+ + GPPG GK+H+ + ++YT +H + + + + +
Sbjct 3257 RSRFIIGPPGAGKTHWLLQQV---QDGDVIYT-PTHQTMLDMIRALGTCRFNVPAGTTL- 3311
Query 5636 PARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK 5695
+F S +V + DE + + D+ + ++
Sbjct 3312 ----------QFPAPSRTGPWVRILAGGWCPGKNSFL--DEAAYCNHLDVLRLLSKTT-- 3357
Query 5696 HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSA 5755
+GD QL P F+S C + I P L T R I D +
Sbjct 3358 -LTCLGDFKQL------------HPVGFDSHCYVF-DIMPQTQLKTIWRFGQNICDAIQP 3403
Query 5756 LVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISP 5815
Y +KL S +N ++ V + R ++P
Sbjct 3404 D-YRDKL-----------------------MSMVNTTRVTYVEK------PVRYGQVLTP 3433
Query 5816 YNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILC 5875
Y+ + T+DSSQG+ +D V T T S N R VAITRA+ I
Sbjct 3434 YHRDREDGA-------ITIDSSQGATFDVV--TLHLPTKDSLNRQRALVAITRARHAIFV 3484
Query 5876 IMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKF 5935
R L + N+A + E + L + + QA L KF
Sbjct 3485 YDPHRQLQSMFDL-PAKGTPVNLAVHRDEQLIVL----DRNNREITVAQA---LGNGDKF 3536
Query 5936 KTEG---------LCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
+ +C D+ G + ++ +GF + + + +
Sbjct 3537 RATDKRVVDSLRAICADLEGSSSPLP--KVAHNLGFYFSPDLTQFAKL 3582
>sp|Q8JUX6|POLN_CHIKS Polyprotein P1234 OS=Chikungunya virus (strain
S27-African prototype) OX=371094 PE=1 SV=1
Length=2474
Score = 78.9 bits (193), Expect = 2e-12, Method: Composition-based stats.
Identities = 40/168 (24%), Positives = 62/168 (37%), Gaps = 30/168 (18%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ +K +DI K + +VNAAN G GV A+ K ES
Sbjct 1333 CAPSYRVKRMDIAKN----DEECVVNAANPRGLPGDGVCKAVYKK-----WPESF----K 1379
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGP---NLNAGEDIQLLKAAYENFNSQ------DIL 1122
N VG + + +H VGP N + E + L AAY + + +
Sbjct 1380 NSATPVGTAKTVMCGTYP--VIHAVGPNFSNYSESEGDRELAAAYREVAKEVTRLGVNSV 1437
Query 1123 LAPLLSAGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
PLLS G++ + L L + + V I DK +++
Sbjct 1438 AIPLLSTGVYSGGKDRLTQSLNHLFTAMDSTDADVVIYCRDKEWEKKI 1485
Score = 40.8 bits (94), Expect = 0.68, Method: Composition-based stats.
Identities = 42/254 (17%), Positives = 77/254 (30%), Gaps = 65/254 (26%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS L + T+ + ++ ++ +R + +
Sbjct 719 VFGVPGSGKSAIIKNLVTRQD----LVTSGKKENCQEITTDVMRQRGLEISARTVDSLLL 774
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5699
C D++ DE + L + A +R + V
Sbjct 775 NGCN----------------------RPVDVLYVDEAFACHSGTLLALIALVRPRQKVVL 812
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
GDP Q + K V RRC + VS+L Y+
Sbjct 813 CGDPKQCGFFNMMQMK----------VNYNHNICTQVYHKSISRRCTLPVTAIVSSLHYE 862
Query 5760 NKLKAHKDKSA-------------------QCFKMFYKGVI----THDVSSA-----INR 5791
K++ + + CF+ + K + H+V +A + R
Sbjct 863 GKMRTTNEYNKPIVVDTTGSTKPDPGDLVLTCFRGWVKQLQIDYRGHEVMTAAASQGLTR 922
Query 5792 PQIGVVREFLTRNP 5805
+ VR+ + NP
Sbjct 923 KGVYAVRQKVNENP 936
>sp|Q6DFV5|HELZ_MOUSE Probable helicase with zinc finger domain
OS=Mus musculus OX=10090 GN=Helz PE=1 SV=2
Length=1964
Score = 78.9 bits (193), Expect = 2e-12, Method: Composition-based stats.
Identities = 65/393 (17%), Positives = 106/393 (27%), Gaps = 91/393 (23%)
Query 5579 STLQGPPGTGKSHFAIGLA---LYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5635
+ GP GTGK+ A L RI+ S++A D + L +
Sbjct 664 VLIIGPYGTGKTFTLAQAAKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQAR 723
Query 5636 PARARVECFDKF-----KVNSTLE-----------------------QYVFCTVNALPET 5667
P RV +++ V T L +
Sbjct 724 P--LRVYFRNRWVKTVHPVVHQYCLISSTQSTFQMPQKEDILKHRVVVVTLSTSQYLCQL 781
Query 5668 T-----ADIVVFDEISMATNYDLSV-VNARLRAKHYVYIGDPAQLPAPRT--LLTKGTLE 5719
V+ DE + A + + + + V GD QL + L
Sbjct 782 DLEPGFFTHVLLDEAAQAMECETIMPLALATKNTRIVLAGDHMQLSPFVYSEFARERNLH 841
Query 5720 PEYFNSVCRLMKTIGP-DMFLGTCRRCPAEIVDTVSALVYDNKLK------AHKDKSAQC 5772
+ + P + L R I++ S L Y+ KL AHKD
Sbjct 842 VSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLT 901
Query 5773 FKMFYKGVITHDVSSAI--NRPQIGVVREFLTRNPAWRKA---------VFISPYNSQNA 5821
F + S+A N VV W A ++PY Q
Sbjct 902 FFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVF 961
Query 5822 ------VASKILGLPTQTVDSSQGSEYDYVIFTQTT------------------------ 5851
++ + + V + QG ++ + +
Sbjct 962 RIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTE 1021
Query 5852 --ETAHSCNVNRFNVAITRAKIGILCIMSDRDL 5882
+ N N AITRA+ + + L
Sbjct 1022 DLDYGFLSNYKLLNTAITRAQSLVAVVGDPVAL 1054
>sp|Q99ZI6|ADPRH_STRP1 Protein-ADP-ribose hydrolase OS=Streptococcus
pyogenes serotype M1 OX=301447 GN=SPy_1216 PE=3 SV=1
Length=270
Score = 74.7 bits (182), Expect = 2e-12, Method: Composition-based stats.
Identities = 31/133 (23%), Positives = 51/133 (38%), Gaps = 18/133 (14%)
Query 1033 MVIVNAANIHLKH-----GGGVAGALNKATNGAMQKESDDYIKLNG-PLTVGGSCLLSGH 1086
IVNAAN L G + A++ ++ + G +G + L S +
Sbjct 99 DAIVNAANSELLGCFSPNHGCIDNAIHTFAGSRLRLACQAIMTEQGRKEAIGQAKLTSAY 158
Query 1087 NL-AKKCLHVVGPNLNAGEDIQ-----LLKAAYENFN------SQDILLAPLLSAGIFGA 1134
+L A +H VGP + G + LL Y + L +S G FG
Sbjct 159 HLPASYIIHTVGPRITKGHHVSPIRADLLARCYRSSLDLAVKAGLTSLAFCSISTGEFGF 218
Query 1135 KPLQSLQVCVQTV 1147
++ Q+ ++TV
Sbjct 219 PKKEAAQIAIKTV 231
>sp|P67344|ADPRH_STAAN Protein-ADP-ribose hydrolase OS=Staphylococcus
aureus (strain N315) OX=158879 GN=SA0314 PE=1 SV=1
Length=266
Score = 74.3 bits (181), Expect = 3e-12, Method: Composition-based stats.
Identities = 34/154 (22%), Positives = 63/154 (41%), Gaps = 23/154 (15%)
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLK------HGGGVAGALNKATNGAMQKESDD 1067
DN+ + DI + IVNAAN H + ++ ++ + +
Sbjct 85 DNIFVWQGDIT----TLKIDAIVNAANSRFLGCMQANHDC-IDNIIHTKAGVQVRLDCAE 139
Query 1068 YIKLNGPLT-VGGSCLLSGHNL-AKKCLHVVGPNLN----AGEDIQLLKAAYENF----- 1116
I+ G VG + G+NL AK +H VGP + + + LL Y +
Sbjct 140 IIRQQGRNEGVGKAKKTRGYNLPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLAD 199
Query 1117 -NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
+S + + +S G+F ++ ++ V+TV +
Sbjct 200 QHSLNHVAFCCISTGVFAFPQDEAAEIAVRTVES 233
>sp|P67343|ADPRH_STAAM Protein-ADP-ribose hydrolase OS=Staphylococcus
aureus (strain Mu50 / ATCC 700699) OX=158878 GN=SAV0325
PE=1 SV=1
Length=266
Score = 74.3 bits (181), Expect = 3e-12, Method: Composition-based stats.
Identities = 34/154 (22%), Positives = 63/154 (41%), Gaps = 23/154 (15%)
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLK------HGGGVAGALNKATNGAMQKESDD 1067
DN+ + DI + IVNAAN H + ++ ++ + +
Sbjct 85 DNIFVWQGDIT----TLKIDAIVNAANSRFLGCMQANHDC-IDNIIHTKAGVQVRLDCAE 139
Query 1068 YIKLNGPLT-VGGSCLLSGHNL-AKKCLHVVGPNLN----AGEDIQLLKAAYENF----- 1116
I+ G VG + G+NL AK +H VGP + + + LL Y +
Sbjct 140 IIRQQGRNEGVGKAKKTRGYNLPAKYIIHTVGPQIRRLPVSKMNQDLLAKCYLSCLKLAD 199
Query 1117 -NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
+S + + +S G+F ++ ++ V+TV +
Sbjct 200 QHSLNHVAFCCISTGVFAFPQDEAAEIAVRTVES 233
>sp|Q306W6|POLN_EEEV1 Polyprotein P1234 OS=Eastern equine encephalitis
virus (strain PE-0.0155) OX=374596 PE=1 SV=3
Length=2471
Score = 78.6 bits (192), Expect = 3e-12, Method: Composition-based stats.
Identities = 51/197 (26%), Positives = 76/197 (39%), Gaps = 32/197 (16%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ DI K VIVNAAN + G GV GAL K GA K P+
Sbjct 1333 VIRGDISKSTD----EVIVNAANNKGQPGAGVCGALYKKWPGAFDKA---------PIAT 1379
Query 1078 GGSCLLSGHNLAKKCLHVVGPNL---NAGEDIQLLKAAY----ENFNS--QDILLAPLLS 1128
G + L+ +H VGPN + E Q L Y + N + + PLLS
Sbjct 1380 GTAHLV---KHTPNIIHAVGPNFSRMSEVEGNQKLSEVYMDIAKIINKERYNKVSIPLLS 1436
Query 1129 AGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQE 1182
G++ + L L + T V I DK +E + D + + E + +
Sbjct 1437 TGVYAGGKDRVMQSLNHLFTAMDTTDADVTIYCLDKQ-WETRIKDAIARKESVEELVEDD 1495
Query 1183 EPPNTEDSKTEEKSVVQ 1199
+P + E + +S +
Sbjct 1496 KPVDIELVRVHPQSSLV 1512
Score = 54.3 bits (129), Expect = 5e-05, Method: Composition-based stats.
Identities = 57/294 (19%), Positives = 96/294 (33%), Gaps = 56/294 (19%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS G+ + R + + + C+ II R
Sbjct 717 VYGVPGSGKS----GIIKSAVTKRDLVVSA----------------KKENCTEIIKDVKR 756
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
+ D +N + + D + DE L + A ++ K V
Sbjct 757 MRGMDV-----AARTVDSVLLNGV-KHPVDTLYIDEAFACHAGTLLALIAIVKPKKVVLC 810
Query 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
GDP Q + K E V RRC + VS L YD
Sbjct 811 GDPKQCGFFNMMCLKVHFNHEICTEVYHK----------SISRRCTRTVTAIVSTLFYDK 860
Query 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
+++ S + D +S + ++ LT W K + I N +
Sbjct 861 RMRTVNPCSDKII---------IDTTSTTKPLKDDII---LTCFRGWVKQLQIDYKNHEI 908
Query 5821 AVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGIL 5874
A+ GL + V + + + ++ QT+E NV +TR + I+
Sbjct 909 MTAAASQGLTRKGVYAVRYKVNENPLYAQTSE--------HVNVLLTRTEKRIV 954
>sp|P42694|HELZ_HUMAN Probable helicase with zinc finger domain
OS=Homo sapiens OX=9606 GN=HELZ PE=1 SV=2
Length=1942
Score = 77.8 bits (190), Expect = 4e-12, Method: Composition-based stats.
Identities = 66/393 (17%), Positives = 112/393 (28%), Gaps = 91/393 (23%)
Query 5579 STLQGPPGTGKSHF---AIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5635
+ GP GTGK+ A+ L RI+ S++A D + L +
Sbjct 664 VLIIGPYGTGKTFTLAQAVKHILQQQETRILICTHSNSAADLYIKDYLHPYVEAGNPQAR 723
Query 5636 PARARVECFDKF-------------------------KVNSTLEQYVFCTVNA---LPET 5667
P RV +++ K + + V T+N L +
Sbjct 724 P--LRVYFRNRWVKTVHPVVHQYCLISSAHSTFQMPQKEDILKHRVVVVTLNTSQYLCQL 781
Query 5668 T-----ADIVVFDEISMATNYDLSV-VNARLRAKHYVYIGDPAQLPAPRT--LLTKGTLE 5719
++ DE + A + + + + V GD QL + L
Sbjct 782 DLEPGFFTHILLDEAAQAMECETIMPLALATQNTRIVLAGDHMQLSPFVYSEFARERNLH 841
Query 5720 PEYFNSVCRLMKTIGP-DMFLGTCRRCPAEIVDTVSALVYDNKLK------AHKDKSAQC 5772
+ + P + L R I++ S L Y+ KL AHKD
Sbjct 842 VSLLDRLYEHYPAEFPCRILLCENYRSHEAIINYTSELFYEGKLMASGKQPAHKDFYPLT 901
Query 5773 FKMFYKGVITHDVSSAI--NRPQIGVVREFLTRNPAWRKA---------VFISPYNSQNA 5821
F + S+A N VV W A ++PY Q
Sbjct 902 FFTARGEDVQEKNSTAFYNNAEVFEVVERVEELRRKWPVAWGKLDDGSIGVVTPYADQVF 961
Query 5822 ------VASKILGLPTQTVDSSQGSEYDYVIFTQTT------------------------ 5851
++ + + V + QG ++ + +
Sbjct 962 RIRAELRKKRLSDVNVERVLNVQGKQFRVLFLSTVRTRHTCKHKQTPIKKKEQLLEDSTE 1021
Query 5852 --ETAHSCNVNRFNVAITRAKIGILCIMSDRDL 5882
+ N N AITRA+ + + L
Sbjct 1022 DLDYGFLSNYKLLNTAITRAQSLVAVVGDPIAL 1054
>sp|Q6GJZ1|ADPRH_STAAR Protein-ADP-ribose hydrolase OS=Staphylococcus
aureus (strain MRSA252) OX=282458 GN=SAR0322 PE=3 SV=1
Length=266
Score = 73.9 bits (180), Expect = 5e-12, Method: Composition-based stats.
Identities = 34/154 (22%), Positives = 63/154 (41%), Gaps = 23/154 (15%)
Query 1014 DNVAIKCVDIVKEAQSANPMVIVNAANIHLK------HGGGVAGALNKATNGAMQKESDD 1067
DN+ + DI + IVNAAN H + ++ ++ + +
Sbjct 85 DNIFVWQGDIT----TLKIDAIVNAANSRFLGCMQANHDC-IDNIIHTKAGVQVRLDCAE 139
Query 1068 YIKLNGPLT-VGGSCLLSGHNL-AKKCLHVVGPNLN----AGEDIQLLKAAYENF----- 1116
I+ G VG + + G+NL AK +H VGP + + + LL Y +
Sbjct 140 IIRQQGRNEGVGKAKITRGYNLPAKYIIHTVGPQIRRLPVSKLNQDLLAKCYLSCLKLAD 199
Query 1117 -NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
S + + +S G+F ++ ++ V+TV +
Sbjct 200 QQSLNHIAFCCISTGVFAFPQDEAAEIAVRTVES 233
>sp|Q306W8|POLN_EEEV8 Polyprotein P1234 OS=Eastern equine encephalitis
virus (strain PE-3.0815) OX=374597 PE=1 SV=3
Length=2474
Score = 77.0 bits (188), Expect = 7e-12, Method: Composition-based stats.
Identities = 45/157 (29%), Positives = 59/157 (38%), Gaps = 31/157 (20%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+ DI K A IVNAAN + G GV GAL K GA K P+
Sbjct 1333 VIRGDISKSTDEA----IVNAANNKGQPGAGVCGALYKKWPGAFDK---------VPIAT 1379
Query 1078 GGSCLLSGHNLAKKCLHVVGPNLNAGEDI---QLLKAAYE------NFNSQDILLAPLLS 1128
G + L+ +H VGPN + ++ Q L Y N + + PLLS
Sbjct 1380 GTAHLV---KHTPNIIHAVGPNFSRVSEVEGNQKLSEVYMDIAKIINRERYNKVSIPLLS 1436
Query 1129 AGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKA 1159
GI+ + L L + T V I DK
Sbjct 1437 TGIYAGGKDRVMQSLNHLFTAMDTTDADVTIYCLDKQ 1473
Score = 56.6 bits (135), Expect = 1e-05, Method: Composition-based stats.
Identities = 57/294 (19%), Positives = 97/294 (33%), Gaps = 56/294 (19%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS G+ + R + + + C+ II R
Sbjct 717 VYGVPGSGKS----GIIKSAVTKRDLVVSA----------------KKENCTEIIKDVKR 756
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYI 5700
+ D +N + + D + DE L + A ++ K V
Sbjct 757 MRGMDI-----AARTVDSVLLNGV-KHPVDTLYIDEAFACHAGTLLALIAIVKPKKVVLC 810
Query 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
GDP Q + K E V RRC + VS L YD
Sbjct 811 GDPKQCGFFNMMCLKVHFNHEICTEVYHK----------SISRRCTKTVTAIVSTLFYDK 860
Query 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
+++ S + +++ +PQ + LT W K + I N +
Sbjct 861 RMRTVNPCSDKI----------IIDTTSTTKPQRDDII--LTCFRGWVKQLQIDYKNHEI 908
Query 5821 AVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGIL 5874
A+ GL + V + + + ++ QT+E NV +TR + I+
Sbjct 909 MTAAASQGLTRKGVYAVRYKVNENPLYAQTSE--------HVNVLLTRTEKRIV 954
>sp|Q9WJB2|RPOA_PRRSR Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain VR-2332) OX=300559
GN=rep PE=1 SV=2
Length=3960
Score = 77.0 bits (188), Expect = 8e-12, Method: Composition-based stats.
Identities = 98/562 (17%), Positives = 183/562 (33%), Gaps = 120/562 (21%)
Query 4814 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA-NQVIVNNLDKSAG 4872
+AA+ D Y + L V+ +V KY + G C + AG
Sbjct 2737 CEDAALKDLSKYDLSTQGFV----LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAG 2792
Query 4873 FPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVS-I 4931
N++ + S + D L A R T+T LK K + RT+ G +
Sbjct 2793 INGNRFPTKDI----QSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNF 2848
Query 4932 CSTMTNRQFHQKLLKSIAA-----TRGATVVIGTSKFYGGWHNMLKTVYSDVETPHL--- 4983
+ H+ +L + + + +G +KF +++TP L
Sbjct 2849 IA-----LAHRAVLSGVTQGFMKKAFNSPIALGKNKF------------KELQTPVLGRC 2891
Query 4984 MGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLY 5043
+ D CDR+ P ++R A+ +L C H + N C ++++
Sbjct 2892 LEADLASCDRSTPAIVRWFAANLLYEL---ACAEEHLPSYVLNCCH----DLLVTQSGAV 2944
Query 5044 VKPGGTSSGDATTAYANSVFN---ICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECL 5100
K GG SSGD T+ +N++++ Q + + G+ ++++
Sbjct 2945 TKRGGLSSGDPITSVSNTIYSLVIYAQHMVLSYFK----SGHPHGLLFLQDQLK------ 2994
Query 5101 YRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNN 5160
+ + K +++ SDD +V Y + +++ +L +Q
Sbjct 2995 --------------FEDMLKVQPLIVYSDD-LVLYAESPTMPNYHWWVEHLNLMLGFQT- 3038
Query 5161 VFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTD 5220
K T +T P S + G V P+ RIL A +
Sbjct 3039 ---DPKK----TAITDSP----SFLGCRIINGRQLV----PNRDRILAALAYHMKASNVS 3083
Query 5221 GTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDN 5280
++ +D+ ++ + + ++ Q RK D YS
Sbjct 3084 EYYASA--AAILMDSCACLEYDPEWFEELVVGIAQCARK----------DGYS------- 3124
Query 5281 TSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYD----HVI 5336
+ F+ +M+ L++ + S CG C C D H
Sbjct 3125 ---FPGTPFFMSMWEK---LRSNY-----EGKKSRVCGYCGAPAPYATACGLDVCIYHTH 3173
Query 5337 STSHKLVLSVNPYVCNAPGCDV 5358
H V + + C
Sbjct 3174 FHQHCPVTIWCGHPAGSGSCSE 3195
Score = 61.6 bits (148), Expect = 4e-07, Method: Composition-based stats.
Identities = 75/404 (19%), Positives = 132/404 (33%), Gaps = 84/404 (21%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALK-YLPIDKCSRII 5635
+ + GPPG GK+++ + ++YT +H + + + + +
Sbjct 3286 RSRFIIGPPGAGKTYWLLQQV---QDGDVIYT-PTHQTMLDMIRALGTCRFNVPAGTTL- 3340
Query 5636 PARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK 5695
+F V S +V + DE + + D+ + ++
Sbjct 3341 ----------QFPVPSRTGPWVRILAGGWCPGKNSFL--DEAAYCNHLDVLRLLSKTT-- 3386
Query 5696 HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSA 5755
+GD QL P F+S C + I P L T R I D +
Sbjct 3387 -LTCLGDFKQL------------HPVGFDSHCYVF-DIMPQTQLKTIWRFGQNICDAIQP 3432
Query 5756 LVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISP 5815
Y +KL S +N ++ V + R ++P
Sbjct 3433 D-YRDKL-----------------------MSMVNTTRVTYVEK------PVRYGQVLTP 3462
Query 5816 YNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILC 5875
Y+ T+DSSQG+ +D V T T S N R VAITRA+ I
Sbjct 3463 YHRDRED-------DAITIDSSQGATFDVV--TLHLPTKDSLNRQRALVAITRARHAIFV 3513
Query 5876 IMSDRD---LYDK-LQFTSLEIPRRNVATLQAENVTGLFKDCS-KIITGLHPTQAPTHLS 5930
R L+D + T + + L + K+C+ G T
Sbjct 3514 YDPHRQLQGLFDLPAKGTPVNLAVHCDGQLIVLDRNN--KECTVAQALGNGDKFRATDKR 3571
Query 5931 VDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
V + +C D+ G + ++ +GF + + + +
Sbjct 3572 VVDSLRA--ICADLEGSSSPLP--KVAHNLGFYFSPDLTQFAKL 3611
Score = 60.5 bits (145), Expect = 7e-07, Method: Composition-based stats.
Identities = 51/250 (20%), Positives = 93/250 (37%), Gaps = 50/250 (20%)
Query 6565 NARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESV------KTQFNYFKKVDGIIQQL 6618
+ +N + V L P ++A + ++G SV + K V G Q L
Sbjct 3623 STQNNEKWPDRLVASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVKGGAQVL 3682
Query 6619 PETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYA-FEHIVYGDFSHGQLGGL 6677
PET F+ R +E+ E++ + E A H GD +GG
Sbjct 3683 PETVFSTGR---------------IEVDCREYLDDREREVAASLPHGFIGDVKGTTVGGC 3727
Query 6678 HLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKS 6737
H + L +P +S + ++K +C++ D+ L D +
Sbjct 3728 HHVTSRY---------LPRVLPKESV--AVVGVSSPGKAAKALCTLTDVYLPDLEAYLHP 3776
Query 6738 QDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQAS-------QAWQPGVAMPNLY 6790
+ SK K+ +D+ E+ M+W KD +T Y +L+ ++ + +P
Sbjct 3777 E---TQSKCWKMMLDFKEVRLMVW-KD---KTAYFQLEGRYFTWYQLASYASYIRVPV-- 3827
Query 6791 KMQRMLLEKC 6800
+ L+ C
Sbjct 3828 -NSTVYLDPC 3836
>sp|O90368|POLN_ONNVS Polyprotein P1234 OS=O'nyong-nyong virus
(strain SG650) OX=374989 PE=1 SV=1
Length=2513
Score = 77.0 bits (188), Expect = 9e-12, Method: Composition-based stats.
Identities = 36/170 (21%), Positives = 59/170 (35%), Gaps = 30/170 (18%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ +K +DI K +VNAAN G GV A+ + ES
Sbjct 1333 CAPSYRVKRMDIAKN----TEECVVNAANPRGVPGDGVCKAVYRK-----WPESF----R 1379
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQ---LLKAAYENFNSQ------DIL 1122
N VG + + +H VGPN + + + L + Y + +
Sbjct 1380 NSATPVGTAKTIMCGQYP--VIHAVGPNFSNYSEAEGDRELASVYREVAKEVSRLGVSSV 1437
Query 1123 LAPLLSAGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKALYEQVVM 1166
PLLS G++ + L L + + V I DK +++
Sbjct 1438 AIPLLSTGVYSGGKDRLLQSLNHLFTAMDSTDADVVIYCRDKEWEKKITE 1487
Score = 39.7 bits (91), Expect = 1.6, Method: Composition-based stats.
Identities = 41/254 (16%), Positives = 76/254 (30%), Gaps = 65/254 (26%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS L + T+ + ++ ++ +R + +
Sbjct 719 VFGVPGSGKSAIIKNLVTRQD----LVTSGKKENCQEISNDVMRQRKLEISARTVDSLLL 774
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5699
C +++ DE + L + A +R + V
Sbjct 775 NGCN----------------------KPVEVLYVDEAFACHSGTLLALIAMVRPRQKVVL 812
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
GDP Q + K V RRC + VS+L Y+
Sbjct 813 CGDPKQCGFFNMMQMK----------VNYNHNICTQVYHKSISRRCTLPVTAIVSSLHYE 862
Query 5760 NKLKAHKDKSA-------------------QCFK-------MFYKGVI--THDVSSAINR 5791
+K++ + + CF+ + Y+G T S + R
Sbjct 863 SKMRTTNEYNQPIVVDTTGITKPEPGDLVLTCFRGWVKQLQIDYRGNEVMTAAASQGLTR 922
Query 5792 PQIGVVREFLTRNP 5805
+ VR+ + NP
Sbjct 923 KGVYAVRQKVNENP 936
>sp|O74465|HRR1_SCHPO Helicase required for RNAi-mediated heterochromatin
assembly 1 OS=Schizosaccharomyces pombe (strain
972 / ATCC 24843) OX=284812 GN=hrr1 PE=1 SV=2
Length=999
Score = 76.3 bits (186), Expect = 1e-11, Method: Composition-based stats.
Identities = 46/253 (18%), Positives = 86/253 (34%), Gaps = 35/253 (14%)
Query 5664 LPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYF 5723
L I +E + + + V IGD QL R + L + F
Sbjct 700 LERINPKICFIEEAADVLEGPIIPAVFP-SLEQLVLIGDHKQL---RPGCSTYALRQDPF 755
Query 5724 N----SVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN------KLKAHKDKSAQCF 5773
N RL++ L RR +I VS++ D K +
Sbjct 756 NLSISMFERLVENDMEYTRLTMQRRMHPQIRRLVSSVYEDLSDYEITKYWPSIPGMGEIR 815
Query 5774 KMFYKGVITHDV---SSAINRPQIGVVREF----LTRNPAWRKAVFISPYNSQNAVASKI 5826
+ F D +S IN + ++ +F + +K ++ Y +Q + ++
Sbjct 816 RFFLTHSRIEDNDGFASKINLFEAQMLVQFAVYLINNGVEPQKITCLTFYAAQKDLIERL 875
Query 5827 LG---------LPTQTVDSSQGSEYDYVIFTQTTE-----TAHSCNVNRFNVAITRAKIG 5872
L + TVD QG E D V+ + + +R V+++RA+ G
Sbjct 876 LSESLNREKHFIKVATVDGYQGEENDVVLLSLVRNNDRTEVGFLSSPHRVCVSLSRARRG 935
Query 5873 ILCIMSDRDLYDK 5885
+ + + + +
Sbjct 936 LFIFGNAQLVAES 948
Score = 37.0 bits (84), Expect = 8.2, Method: Composition-based stats.
Identities = 21/66 (32%), Positives = 33/66 (50%), Gaps = 6/66 (9%)
Query 5564 SSNVANYQKVGMQKYSTLQGPPGTGKSHFAIG-----LALYYPSARIVYTAC-SHAAVDA 5617
SS + YQ + ++ S +QGPPGTGKS + L + + AC ++ AVD
Sbjct 374 SSQLKAYQSMLTKRLSIIQGPPGTGKSFVTLKAIETLLENTHSHVLPILVACQTNHAVDQ 433
Query 5618 LCEKAL 5623
+ + L
Sbjct 434 ILIRLL 439
>sp|O90370|POLN_ONNVI Polyprotein P1234 OS=O'nyong-nyong virus
(strain Igbo Ora) OX=79899 PE=3 SV=1
Length=2513
Score = 76.6 bits (187), Expect = 1e-11, Method: Composition-based stats.
Identities = 37/170 (22%), Positives = 60/170 (35%), Gaps = 30/170 (18%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ +K +DI K +VNAAN G GV A+ + ES
Sbjct 1333 CAPSYRVKRMDIAKN----TEECVVNAANPRGVPGDGVCKAVYRK-----WPESF----R 1379
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQ---LLKAAYENFNSQ------DIL 1122
N VG + + +H VGPN + + + L +AY + +
Sbjct 1380 NSATPVGTAKTIMCGQYP--VIHAVGPNFSNYSEAEGDRELASAYREVAKEVSRLGVSSV 1437
Query 1123 LAPLLSAGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKALYEQVVM 1166
PLLS G++ + L L + + V I DK +++
Sbjct 1438 AIPLLSTGVYSGGKDRLLQSLNHLFAAMDSTDADVVIYCRDKEWEKKITE 1487
Score = 39.7 bits (91), Expect = 1.8, Method: Composition-based stats.
Identities = 41/254 (16%), Positives = 76/254 (30%), Gaps = 65/254 (26%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS L + T+ + ++ ++ +R + +
Sbjct 719 VFGVPGSGKSAIIKNLVTRQD----LVTSGKKENCQEISNDVMRQRKLEISARTVDSLLL 774
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5699
C +++ DE + L + A +R + V
Sbjct 775 NGCN----------------------KPVEVLYVDEAFACHSGTLLALIAMVRPRQKVVL 812
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
GDP Q + K V RRC + VS+L Y+
Sbjct 813 CGDPKQCGFFNMMQMK----------VNYNHNICTQVYHKSISRRCTLPVTAIVSSLHYE 862
Query 5760 NKLKAHKDKSA-------------------QCFK-------MFYKGVI--THDVSSAINR 5791
+K++ + + CF+ + Y+G T S + R
Sbjct 863 SKMRTTNEYNQPIVVDTTGTTKPEPGDLVLTCFRGWVKQLQIDYRGNEVMTAAASQGLTR 922
Query 5792 PQIGVVREFLTRNP 5805
+ VR+ + NP
Sbjct 923 KGVYAVRQKVNENP 936
>sp|Q9YN02|RPOA_PRRS1 Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain 16244B) OX=300561
GN=rep PE=1 SV=3
Length=3961
Score = 76.6 bits (187), Expect = 1e-11, Method: Composition-based stats.
Identities = 97/554 (18%), Positives = 180/554 (32%), Gaps = 104/554 (19%)
Query 4814 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINA-NQVIVNNLDKSAG 4872
+AA+ D Y + L V+ +V KY + G C + AG
Sbjct 2738 CEDAALKDLSKYDLSTQGFV----LPGVLRLVRKYLFAHVGKCPPVHRPSTYPAKNSMAG 2793
Query 4873 FPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSIC 4932
N++ + S + D L A R T+T LK K + RT+ G +
Sbjct 2794 INGNRFPTKDI----QSVPEIDVLCAQAVRENWQTVTPCTLKKQYCGKKKTRTILGTNNF 2849
Query 4933 STMTNRQFHQKLLKSIAATR-GATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKC 4991
+ +R + + + + +G +KF K + + V L D C
Sbjct 2850 IALAHRAALSGVTQGFMKKAFNSPIALGKNKF--------KELQTSVLGRCL-EADLASC 2900
Query 4992 DRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSS 5051
DR+ P ++R A+ +L C H + N C ++++ K GG SS
Sbjct 2901 DRSTPAIVRWFAANLLYEL---ACAEEHLPSYVLNCCH----DLLVTQSGAVTKRGGLSS 2953
Query 5052 GDATTAYANSVFN---ICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDH 5108
GD T+ +N++++ Q + + G+ ++++
Sbjct 2954 GDPITSVSNTIYSLVIYAQHMVLSYFK----SGHPHGLLFLQDQLK-------------- 2995
Query 5109 EFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKC 5168
+ + K +++ SDD +V Y + +++ +L +Q K
Sbjct 2996 ------FEDMLKVQPLIVYSDD-LVLYAESPTMPNYHWWVEHLNLMLGFQT----DPKK- 3043
Query 5169 WTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERF 5228
T +T P S + G V P+ RIL A +
Sbjct 3044 ---TAITDSP----SFLGCRIINGRQLV----PNRDRILAALAYHMKASNVSEYYASA-- 3090
Query 5229 VSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPE 5288
++ +D+ ++ + + ++ Q RK D YS +
Sbjct 3091 AAILMDSCACLEYDPEWFEELVVGIAQCARK----------DGYS----------FPGTP 3130
Query 5289 FYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYD----HVISTSHKLVL 5344
F+ +M+ L++ + S CG C C D H H V
Sbjct 3131 FFMSMWEK---LRSNY-----EGKKSRVCGYCGAPAPYATACGLDVCIYHTHFHQHCPVT 3182
Query 5345 SVNPYVCNAPGCDV 5358
+ + C
Sbjct 3183 IWCGHPAGSGSCSE 3196
Score = 62.4 bits (150), Expect = 2e-07, Method: Composition-based stats.
Identities = 49/250 (20%), Positives = 90/250 (36%), Gaps = 50/250 (20%)
Query 6565 NARNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESV------KTQFNYFKKVDGIIQQL 6618
+N + V L P ++A + ++G SV + K V G Q L
Sbjct 3624 TTQNNEKWPDRLVASLRPIHKYSRACIGAGYMVGPSVFLGTPGVVSYYLTKFVKGEAQLL 3683
Query 6619 PETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYA-FEHIVYGDFSHGQLGGL 6677
PET F+ R +E+ E++ + E A H GD +GG
Sbjct 3684 PETVFSTGR---------------IEVDCREYLDDREREVAASLPHAFIGDVKGTTVGGC 3728
Query 6678 HLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKS 6737
H + L +P +S + ++K +C++ D+ L D +
Sbjct 3729 HHVTSRY---------LPRVLPKESV--AVVGVSSPGKAAKALCTLTDVYLPDLEAYLHP 3777
Query 6738 QDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQAS-------QAWQPGVAMPNLY 6790
+ SK K+ +D+ E+ M+W +T Y +L+ ++ + +P
Sbjct 3778 E---TQSKCWKMMLDFKEVRLMVWRD----KTAYFQLEGRYFTWYQLASYASYIRVPV-- 3828
Query 6791 KMQRMLLEKC 6800
+ L+ C
Sbjct 3829 -NSTVYLDPC 3837
Score = 62.0 bits (149), Expect = 3e-07, Method: Composition-based stats.
Identities = 75/404 (19%), Positives = 132/404 (33%), Gaps = 84/404 (21%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALK-YLPIDKCSRII 5635
+ + GPPG GK+++ + ++YT +H + + + + +
Sbjct 3287 RSRFIIGPPGAGKTYWLLQQV---QDGDVIYT-PTHQTMLDMIRALGTCRFNVPAGTTL- 3341
Query 5636 PARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK 5695
+F V S +V + DE + + D+ + ++
Sbjct 3342 ----------QFPVPSRTGPWVRILAGGWCPGKNSFL--DEAAYCNHLDVLRLLSKTT-- 3387
Query 5696 HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSA 5755
+GD QL P F+S C + I P L T R I D +
Sbjct 3388 -LTCLGDFKQL------------HPVGFDSHCYVF-DIMPQTQLKTIWRFGQNICDAIQP 3433
Query 5756 LVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISP 5815
Y +KL S +N ++ V + R ++P
Sbjct 3434 D-YRDKL-----------------------MSMVNTTRVTYVEK------PVRYGQVLTP 3463
Query 5816 YNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILC 5875
Y+ T+DSSQG+ +D V T T S N R VAITRA+ I
Sbjct 3464 YHRDRED-------DAITIDSSQGATFDVV--TLHLPTKDSLNRQRALVAITRARHAIFV 3514
Query 5876 IMSDRD---LYDK-LQFTSLEIPRRNVATLQAENVTGLFKDCS-KIITGLHPTQAPTHLS 5930
R L+D + T + + L + K+C+ G T
Sbjct 3515 YDPHRQLQGLFDLPAKGTPVNLAVHRDGQLIVLDRNN--KECTVAQALGNGDKFRATDKR 3572
Query 5931 VDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
V + +C D+ G + ++ +GF + + + +
Sbjct 3573 VVDSLRA--ICADLEGSSSPLP--KVAHNLGFYFSPDLTQFAKL 3612
>sp|Q93RG0|ADPRH_TREMD Protein-ADP-ribose hydrolase OS=Treponema
medium OX=58231 PE=3 SV=1
Length=261
Score = 72.4 bits (176), Expect = 1e-11, Method: Composition-based stats.
Identities = 27/140 (19%), Positives = 50/140 (36%), Gaps = 16/140 (11%)
Query 1026 EAQSANPMVIVNAANIHLKH-----GGGVAGALNKATNGAMQKESDDYIKLNG-PLTVGG 1079
+ + IVNAAN + + ++ ++ ++ G G
Sbjct 93 DITTLKVDAIVNAANSGMTGCWQPCHACIDNCIHTFAGVQLRTVCAGIMQEQGHEEPTGT 152
Query 1080 SCLLSGHNL-AKKCLHVVGPNLNAG---EDIQLLKAAYENF------NSQDILLAPLLSA 1129
+ + NL K LH VGP ++ D LL +Y + N + +S
Sbjct 153 AKITPAFNLPCKYVLHTVGPIISGQLTDRDCTLLANSYTSCLNLAAENGVKSIAFCCIST 212
Query 1130 GIFGAKPLQSLQVCVQTVRT 1149
G+F ++ ++ V TV
Sbjct 213 GVFRFPAQKAAEIAVATVED 232
>sp|Q99IE5|POLN_RUBVV Non-structural polyprotein p200 OS=Rubella
virus (strain TO-336) OX=376264 PE=3 SV=1
Length=2116
Score = 76.3 bits (186), Expect = 1e-11, Method: Composition-based stats.
Identities = 40/182 (22%), Positives = 64/182 (35%), Gaps = 20/182 (11%)
Query 970 TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQS 1029
+ + L+ E S+ + P+ + + Y + V ++ DI+
Sbjct 775 SAGPADRARHAELEVAYEPSDPPTPTKADPDSDIVE--SYARAAGPVHLRVRDIMDPPPG 832
Query 1030 ANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA 1089
V+VNAAN L G GV GA+ A+ + P G + GH
Sbjct 833 CK--VVVNAANEGLLAGSGVCGAIFANATAALAADCRRLA----PCPTGEAVATPGHGCG 886
Query 1090 -KKCLHVVGPN-----LNAGEDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPL 1137
+H V P E LL+ AY + + PLL AG++G
Sbjct 887 YTHIIHAVAPRRPRDPAALEEGEALLERAYRSIVALAAARRWACVACPLLGAGVYGWSAA 946
Query 1138 QS 1139
+S
Sbjct 947 ES 948
>sp|Q99IE7|POLN_RUBVO Non-structural polyprotein p200 OS=Rubella
virus (strain TO-336 vaccine) OX=376265 PE=3 SV=1
Length=2116
Score = 76.3 bits (186), Expect = 1e-11, Method: Composition-based stats.
Identities = 40/182 (22%), Positives = 64/182 (35%), Gaps = 20/182 (11%)
Query 970 TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQS 1029
+ + L+ E S+ + P+ + + Y + V ++ DI+
Sbjct 775 SAGPADRARHAELEVAYEPSDPPTPTKADPDSDIVE--SYARAAGPVHLRVRDIMDPPPG 832
Query 1030 ANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA 1089
V+VNAAN L G GV GA+ A+ + P G + GH
Sbjct 833 CK--VVVNAANEGLLAGSGVCGAIFANATAALAADCRRLA----PCPTGEAVATPGHGCG 886
Query 1090 -KKCLHVVGPN-----LNAGEDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPL 1137
+H V P E LL+ AY + + PLL AG++G
Sbjct 887 YTHIIHAVAPRRPRDPAALEEGEALLERAYRSIVALAAARRWACVACPLLGAGVYGWSAA 946
Query 1138 QS 1139
+S
Sbjct 947 ES 948
>sp|P13886|POLN_ONNVG Polyprotein P1234 OS=O'nyong-nyong virus
(strain Gulu) OX=11028 PE=3 SV=2
Length=2514
Score = 75.9 bits (185), Expect = 2e-11, Method: Composition-based stats.
Identities = 36/170 (21%), Positives = 59/170 (35%), Gaps = 30/170 (18%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
+ +K +DI K +VNAAN G GV A+ + ES
Sbjct 1333 CAPSYRVKRMDIAKN----TEECVVNAANPRGVPGDGVCKAVYRK-----WPESF----R 1379
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQ---LLKAAYENFNSQ------DIL 1122
N VG + + +H VGPN + + + L + Y + +
Sbjct 1380 NSATPVGTAKTIMCGQYP--VIHAVGPNFSNYSEAEGDRELASVYREVAKEVSRLGVSSV 1437
Query 1123 LAPLLSAGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKALYEQVVM 1166
PLLS G++ + L L + + V I DK +++
Sbjct 1438 AIPLLSTGVYSGGKDRLLQSLNHLFAAMDSTDADVVIYCRDKEWEKKITE 1487
Score = 39.7 bits (91), Expect = 1.7, Method: Composition-based stats.
Identities = 41/254 (16%), Positives = 76/254 (30%), Gaps = 65/254 (26%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS L + T+ + ++ ++ +R + +
Sbjct 719 VFGVPGSGKSAIIKNLVTRQD----LVTSGKKENCQEISNDVMRQRKLEISARTVDSLLL 774
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5699
C +++ DE + L + A +R + V
Sbjct 775 NGCN----------------------KPVEVLYVDEAFACHSGTLLALIAMVRPRQKVVL 812
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
GDP Q + K V RRC + VS+L Y+
Sbjct 813 CGDPKQCGFFNMMQMK----------VNYNHNICTQVYHKSISRRCTLPVTAIVSSLHYE 862
Query 5760 NKLKAHKDKSA-------------------QCFK-------MFYKGVI--THDVSSAINR 5791
+K++ + + CF+ + Y+G T S + R
Sbjct 863 SKMRTTNEYNQPIVVDTTGITKPEPGDLVLTCFRGWVKQLQIDYRGNEVMTAAASQGLTR 922
Query 5792 PQIGVVREFLTRNP 5805
+ VR+ + NP
Sbjct 923 KGVYAVRQKVNENP 936
>sp|F6QXW0|DNA2_XENTR DNA replication ATP-dependent helicase/nuclease
DNA2 OS=Xenopus tropicalis OX=8364 GN=dna2 PE=3 SV=1
Length=1048
Score = 75.1 bits (183), Expect = 2e-11, Method: Composition-based stats.
Identities = 67/387 (17%), Positives = 110/387 (28%), Gaps = 92/387 (24%)
Query 5576 QKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPI------- 5628
+ Y+ + G PGTGK+ L + C+ VD E A +
Sbjct 642 KDYTLIVGMPGTGKTTTICTLVST-----LHLKTCTSCLVDDHREAAGTHRSHRHSKGTV 696
Query 5629 -------------------DKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTA 5669
KC E K+ S + +
Sbjct 697 NLGKQKRQHRVTSTTSSTSAKCRSKTEPAVSAENKKLQKLISGSHVCIMVNGHKTFSQNN 756
Query 5670 DIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRL 5729
I+ FD I + L + A H + G +L+ + + F RL
Sbjct 757 YIIFFDNILLLKKLPLHYMCAFALIHHQCFKG----CVKSVSLVRELGMSESLFK---RL 809
Query 5730 MKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD---------------------- 5767
+ + L R ++I+ + LVY+ +L+ D
Sbjct 810 ERNQEAVVQLTVQYRMNSQIMALSNKLVYEGRLECASDRVSNAVVKLPHIKTLLLELEFR 869
Query 5768 --------------KSAQCFKMFYK--GVITHDVSSAINRPQIGVV----REFLTRNPAW 5807
+ CF K + T + N + +V + FL
Sbjct 870 ESQESMWIKDVLEPSNPVCFLNTEKIPALETEEKGGISNWIEAKLVFCLTKLFLKAGCRP 929
Query 5808 RKAVFISPYNSQNAVAS------KILGLPTQTVDSSQGSEYDYVIFTQTTET------AH 5855
I+PY Q V S + TVD QG + +I +
Sbjct 930 SDIGIIAPYRQQLKVISNYFNSLSASAVEVNTVDKYQGRDKSVIIVSFVRSNIDGKLGDL 989
Query 5856 SCNVNRFNVAITRAKIGILCIMSDRDL 5882
+ R NVA+TRAK ++ + L
Sbjct 990 LKDWRRLNVALTRAKHKLIMLGCVPTL 1016
>sp|Q9J6K9|POLN_RUBVD Non-structural polyprotein p200 OS=Rubella
virus (strain Cendehill) OX=376266 PE=3 SV=2
Length=2116
Score = 75.1 bits (183), Expect = 3e-11, Method: Composition-based stats.
Identities = 48/233 (21%), Positives = 77/233 (33%), Gaps = 21/233 (9%)
Query 970 TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQS 1029
+ + L+ E S + P+ + + Y + V ++ DI+
Sbjct 775 PAEPADRARDAELEVAYEPSGPPTSTKADPDSDIVE--SYARAAGPVHLRVRDIMDPPPG 832
Query 1030 ANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA 1089
V+VNAAN L G GV GA+ A+ + P G + GH
Sbjct 833 CK--VVVNAANEGLLAGSGVCGAIFANATAALAADCRRLA----PCPTGEAVATPGHGCG 886
Query 1090 -KKCLHVVGPN-----LNAGEDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPL 1137
+H V P E LL+ AY + + PLL AG++G
Sbjct 887 YTHIIHAVAPRRPRDPAALEEGEALLERAYRSIVALAAARRWAYVACPLLGAGVYGWSAA 946
Query 1138 QS-LQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTED 1189
+S T V ++ + + L A ++ PP TE
Sbjct 947 ESLRAALAATRAEPVERVSLHICHPDRATLTHASVLVGAGLAARRVSPPPTEP 999
>sp|P87515|POLN_BFV Polyprotein P1234 OS=Barmah forest virus OX=11020
PE=3 SV=3
Length=2411
Score = 75.1 bits (183), Expect = 3e-11, Method: Composition-based stats.
Identities = 38/162 (23%), Positives = 55/162 (34%), Gaps = 30/162 (19%)
Query 1018 IKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTV 1077
+K DI +A +VNAAN G GV GA+ + A
Sbjct 1337 VKRGDI----SNAPEDAVVNAANQQGVKGAGVCGAIYRKWPDAFGD---------VATPT 1383
Query 1078 GGSCLLSGHNLAKKCLHVVGPNLNAGEDIQ---LLKAAYENF------NSQDILLAPLLS 1128
G + S K +H VGPN + + + L +AY + PLLS
Sbjct 1384 GTAV--SKSVQDKLVIHAVGPNFSKCSEEEGDRDLASAYRAAAEIVMDKKITTVAVPLLS 1441
Query 1129 AGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
GI+ + L L V I DK +++
Sbjct 1442 TGIYAGGKNRVEQSLNHLFTAFDNTDADVTIYCMDKTWEKKI 1483
Score = 43.5 bits (101), Expect = 0.10, Method: Composition-based stats.
Identities = 56/298 (19%), Positives = 99/298 (33%), Gaps = 63/298 (21%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS AI S ++ + C + + + + RI
Sbjct 717 VYGVPGSGKS--AIIKNTVTMSDLVL------SGKKENCLEIMNDVLKHRALRI------ 762
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH-YVY 5699
T + +N + + T +I+ DE L A +R K V
Sbjct 763 -----------TAKTVDSVLLNGV-KHTPNILYIDEAFSCHAGTLLATIAIVRPKQKVVL 810
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
GDP Q + K + + V RRC +I VS L Y
Sbjct 811 CGDPKQCGFFNMMQLKVNYNHDICSEVFHK----------SISRRCTQDITAIVSKLHYQ 860
Query 5760 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5819
++++ + KG I D + + ++ LT W K + Q
Sbjct 861 DRMRTTNPR---------KGDIIIDTTGTTKPAKTDLI---LTCFRGWVKQL------QQ 902
Query 5820 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTT---ETAHSCNVNRFNVAITRAKIGIL 5874
+ ++++ T +SQG V +T ++ NV +TR + ++
Sbjct 903 DYRGNEVM-----TAAASQGLTRASVYAVRTKVNENPLYAQTSEHVNVLLTRTENKLV 955
>sp|P13888|POLN_RRVT Polyprotein nsP1234 (Fragment) OS=Ross river
virus (strain T48) OX=11032 PE=1 SV=2
Length=1149
Score = 74.3 bits (181), Expect = 5e-11, Method: Composition-based stats.
Identities = 38/148 (26%), Positives = 59/148 (40%), Gaps = 26/148 (18%)
Query 1032 PMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKK 1091
+VNAAN G GV A+ + K D + VG + L+ + +
Sbjct 16 EEAVVNAANAKGTVGDGVCRAVAR-------KWPDSF--KGAATPVGTAKLVQANGM--N 64
Query 1092 CLHVVGPNLNAGEDIQ---LLKAAYE------NFNSQDILLAPLLSAGIFGA------KP 1136
+H VGPN + + + L AAY N ++ + PLLS G+F +
Sbjct 65 VIHAVGPNFSTVTEAEGDRELAAAYRAVAGIINASNIKSVAIPLLSTGVFSGGKDRVMQS 124
Query 1137 LQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
L L + T V I DKA +++
Sbjct 125 LNHLFTAMDTTDADVVIYCRDKAWEKKI 152
>sp|P13887|POLN_RRVN Polyprotein P1234 OS=Ross river virus (strain
NB5092) OX=11031 PE=3 SV=2
Length=2480
Score = 73.6 bits (179), Expect = 9e-11, Method: Composition-based stats.
Identities = 38/148 (26%), Positives = 59/148 (40%), Gaps = 26/148 (18%)
Query 1032 PMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKK 1091
+VNAAN G GV A+ + K D + VG + L+ + +
Sbjct 1347 EEAVVNAANAKGTVGVGVCRAVAR-------KWPDSF--KGAATPVGTAKLVQANGM--N 1395
Query 1092 CLHVVGPNLNAGEDIQ---LLKAAYE------NFNSQDILLAPLLSAGIFGA------KP 1136
+H VGPN + + + L AAY N ++ + PLLS G+F +
Sbjct 1396 VIHAVGPNFSTVTEAEGDRELAAAYRAVAGIINASNIKSVAIPLLSTGVFSGGKDRVMQS 1455
Query 1137 LQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
L L + T V I DKA +++
Sbjct 1456 LNHLFTAMDTTDADVVIYCRDKAWEKKI 1483
>sp|Q8CFQ3|AQR_MOUSE RNA helicase aquarius OS=Mus musculus OX=10090
GN=Aqr PE=1 SV=2
Length=1481
Score = 73.2 bits (178), Expect = 1e-10, Method: Composition-based stats.
Identities = 57/296 (19%), Positives = 99/296 (33%), Gaps = 71/296 (24%)
Query 5649 VNSTLEQYVFCTVNALPETT-------ADIVVFDEISMATNYDLSVVNARL--------R 5693
V + CT AL D ++ +E + + + + L R
Sbjct 1033 VKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIE-TFIPLLLQNPQDGFSR 1091
Query 5694 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRR-----CP-- 5746
K ++ IGD QLP + + R ++ P + L R C
Sbjct 1092 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 1151
Query 5747 ----------------AEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAI- 5789
E + L+YD +L +D ++GV + +
Sbjct 1152 NWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVED---------FQGVGESEPNPYFY 1202
Query 5790 -NRPQIGVVREF-----LTRNPAWRKAVFISPYNSQNAVASKILGL------------PT 5831
N + V L PA + ++ ++ YN Q + I+
Sbjct 1203 QNLGEAEYVVALFMYMCLLGYPADKISI-LTTYNGQKHLIRDIINRRCGNNPLIGRPNKV 1261
Query 5832 QTVDSSQGSEYDYVIFTQ--TTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDK 5885
TVD QG + DY++ + T H +V R VA++RA++G L I + L+
Sbjct 1262 TTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLG-LYIFARVSLFQN 1316
Score = 39.7 bits (91), Expect = 1.6, Method: Composition-based stats.
Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 10/95 (11%)
Query 5538 APTLVPQEHYVRITGLYPTLNISDEFSSNVANYQ----KVGMQK-YSTLQGPPGTGKSHF 5592
A TL+ + H + G YP N + + Q + GMQ + + GPPGTGK+
Sbjct 774 AKTLIVEPHVIPNRGPYP-YNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDV 832
Query 5593 AI----GLALYYPSARIVYTACSHAAVDALCEKAL 5623
A+ + +P R + S+ A++ L EK +
Sbjct 833 AVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIM 867
>sp|O60306|AQR_HUMAN RNA helicase aquarius OS=Homo sapiens OX=9606
GN=AQR PE=1 SV=4
Length=1485
Score = 73.2 bits (178), Expect = 1e-10, Method: Composition-based stats.
Identities = 57/296 (19%), Positives = 99/296 (33%), Gaps = 71/296 (24%)
Query 5649 VNSTLEQYVFCTVNALPETT-------ADIVVFDEISMATNYDLSVVNARL--------R 5693
V + CT AL D ++ +E + + + + L R
Sbjct 1029 VKEAKIIAMTCTHAALKRHDLVKLGFKYDNILMEEAAQILEIE-TFIPLLLQNPQDGFSR 1087
Query 5694 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRR-----CP-- 5746
K ++ IGD QLP + + R ++ P + L R C
Sbjct 1088 LKRWIMIGDHHQLPPVIKNMAFQKYSNMEQSLFTRFVRVGVPTVDLDAQGRARASLCNLY 1147
Query 5747 ----------------AEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAI- 5789
E + L+YD +L +D ++GV + +
Sbjct 1148 NWRYKNLGNLPHVQLLPEFSTANAGLLYDFQLINVED---------FQGVGESEPNPYFY 1198
Query 5790 -NRPQIGVVREF-----LTRNPAWRKAVFISPYNSQNAVASKILGL------------PT 5831
N + V L PA + ++ ++ YN Q + I+
Sbjct 1199 QNLGEAEYVVALFMYMCLLGYPADKISI-LTTYNGQKHLIRDIINRRCGNNPLIGRPNKV 1257
Query 5832 QTVDSSQGSEYDYVIFTQ--TTETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDK 5885
TVD QG + DY++ + T H +V R VA++RA++G L I + L+
Sbjct 1258 TTVDRFQGQQNDYILLSLVRTRAVGHLRDVRRLVVAMSRARLG-LYIFARVSLFQN 1312
Score = 39.7 bits (91), Expect = 1.6, Method: Composition-based stats.
Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 10/95 (11%)
Query 5538 APTLVPQEHYVRITGLYPTLNISDEFSSNVANYQ----KVGMQK-YSTLQGPPGTGKSHF 5592
A TL+ + H + G YP N + + Q + GMQ + + GPPGTGK+
Sbjct 774 AKTLIVEPHVIPNRGPYP-YNQPKRNTIQFTHTQIEAIRAGMQPGLTMVVGPPGTGKTDV 832
Query 5593 AI----GLALYYPSARIVYTACSHAAVDALCEKAL 5623
A+ + +P R + S+ A++ L EK +
Sbjct 833 AVQIISNIYHNFPEQRTLIVTHSNQALNQLFEKIM 867
>sp|Q6QLN1|POLN_AHEV Non-structural polyprotein pORF1 OS=Avian
hepatitis E virus (isolate Chicken/California/Meng) OX=516993
GN=ORF1 PE=3 SV=1
Length=1531
Score = 72.8 bits (177), Expect = 1e-10, Method: Composition-based stats.
Identities = 40/176 (23%), Positives = 63/176 (36%), Gaps = 12/176 (7%)
Query 986 TEQSEIEPEPEPTPE---EPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIH 1042
E SE +P PT E P+ G ++ + IV +VN AN
Sbjct 588 PEVSESQPGLTPTREVTNMPLPPQRGQEEVLAVLPSGARVIVGNLLDVAADWLVNPANRD 647
Query 1043 LKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVVGPNLNA 1102
+ GGG+ G ++ + + L G G K +H GP+
Sbjct 648 HQPGGGLCGMFHRRW-PHLWPVCGEV----QDLPTGPVIFQQG---PPKVIHAPGPDYRI 699
Query 1103 GEDIQLLKAAYENFNS-QDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVND 1157
D L+ Y + + +PL+SAGI+ A +S + T R + V
Sbjct 700 KPDPDGLRRVYAVVHQAHGTVASPLISAGIYRAPARESFEAWAATARDGDLLVVQR 755
Score = 47.0 bits (110), Expect = 0.010, Method: Composition-based stats.
Identities = 62/383 (16%), Positives = 113/383 (30%), Gaps = 104/383 (27%)
Query 5554 YPTLNISDEFSSNVANYQKVGMQ-KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSH 5612
Y + ++ V + M KY+ + G PG+GKS
Sbjct 788 YGLATEPEPYNELVKGVEVAPMTVKYALIAGVPGSGKS---------------------- 825
Query 5613 AAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIV 5672
++VD I P + ++ +A PE V
Sbjct 826 SSVD-----------HRGAVVITPTKTLAR---EWSARGATAVTPHVAASAAPEGR---V 868
Query 5673 VFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKT 5732
+ DE + L V + R RA+ V +GDP Q+PA L+ + +
Sbjct 869 IVDEAYAIPPH-LLVASLR-RARDVVMLGDPHQIPA---------LDFDGRCLTSAVDLG 917
Query 5733 IGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRP 5792
+ P + RCP ++ +F + +++
Sbjct 918 LQPTSWRTVSHRCPWDVC------------------------IFLRTDYPTITTTSRVLR 953
Query 5793 QIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTE 5852
+ E + +K VF N + TV +QGS +D T +
Sbjct 954 SVVFTGETI-----GQKIVFTQVAKQSNPGSI--------TVHEAQGSTFDQTTIIATLD 1000
Query 5853 TAHSCNVNR--FNVAITRAKI--------GILC-IMSDRDLYDKLQFTSLEIPRRNVATL 5901
+R VA+TR + G+L I +++ ++ + A +
Sbjct 1001 ARGLIASSRAHAIVALTRHRERCSVIDVGGVLVEIGVTDAMFNNIEMQLVRPDAAAPAGV 1060
Query 5902 QAENVTGLFKDCSKIITGLHPTQ 5924
D + + P
Sbjct 1061 LRAPD-----DTVDGLLDIPPAH 1078
>sp|Q8QZ73|POLN_MAYAB Polyprotein P1234 OS=Mayaro virus (strain
Brazil) OX=374990 PE=1 SV=3
Length=2437
Score = 72.0 bits (175), Expect = 3e-10, Method: Composition-based stats.
Identities = 40/168 (24%), Positives = 58/168 (35%), Gaps = 30/168 (18%)
Query 1012 LTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKL 1071
A+K DI +VNAAN + G GV A+ + A
Sbjct 1334 CAPAYAVKRADIATAI----EDAVVNAANHRGQVGDGVCRAVARKWPQAF---------R 1380
Query 1072 NGPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYE---------NFNSQDIL 1122
N VG + + +H VGPN N + + + N S +
Sbjct 1381 NAATPVGTAKTVKCDE--TYIIHAVGPNFNNTSEAEGDRDLAAAYRAVAAEINRLSISSV 1438
Query 1123 LAPLLSAGIFGA------KPLQSLQVCVQTVRTQVYIAVNDKALYEQV 1164
PLLS GIF A + L L + T +V I DK +++
Sbjct 1439 AIPLLSTGIFSAGKDRVHQSLSHLLAAMDTTEARVTIYCRDKTWEQKI 1486
Score = 40.8 bits (94), Expect = 0.66, Method: Composition-based stats.
Identities = 51/297 (17%), Positives = 90/297 (30%), Gaps = 69/297 (23%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS L L K + C I+
Sbjct 720 VFGVPGSGKSGIIKSLVTR----------------GDLVASGKK----ENCQEIM---LD 756
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRA-KHYVY 5699
V+ + ++ T + +N + +T D++ DE L + A +R K V
Sbjct 757 VKRYRD--LDMTAKTVDSVLLNGVKQTV-DVLYVDEAFACHAGTLLALIATVRPRKKVVL 813
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
GDP Q + + V RRC I VS L Y+
Sbjct 814 CGDPKQCGFFNLMQLQVNFNHNICTEVDHK----------SISRRCTLPITAIVSTLHYE 863
Query 5760 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYN-- 5817
+++ N+P V+ + + R+ + ++ +
Sbjct 864 GRMRTTNP---------------------YNKP---VIIDTTGQTKPNREDIVLTCFRGW 899
Query 5818 -SQNAVASKILGLPTQTVDSSQGSEYDYVIFT---QTTETAHSCNVNRFNVAITRAK 5870
Q + + G T +SQG V ++ + NV +TR +
Sbjct 900 VKQLQLDYR--GHEVMTAAASQGLTRKGVYAVRMKVNENPLYAQSSEHVNVLLTRTE 954
>sp|Q9YBE9|Y1648_AERPE Uncharacterized protein APE_1648.1 OS=Aeropyrum
pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 /
NBRC 100138 / K1) OX=272557 GN=APE_1648.1 PE=4 SV=2
Length=189
Score = 66.6 bits (161), Expect = 3e-10, Method: Composition-based stats.
Identities = 32/136 (24%), Positives = 56/136 (41%), Gaps = 16/136 (12%)
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPL 1075
+A+ D+ K +VN AN + GGG AGAL +A +++E+ P+
Sbjct 11 LAVSMGDLTK----VRAEAVVNPANSLMIMGGGAAGALKRAGGSVIEEEAM----RKAPV 62
Query 1076 TVGGSCLLSGHNL-AKKCLHV-----VGPNLNAGEDIQLLKAAYENFNSQDI--LLAPLL 1127
VG + + SG +L A+ +H G + + AA + I + P +
Sbjct 63 PVGEAVITSGGSLPARFVIHAPTMEEPGMRIPLVNAFKASYAALRLASEAGIESVAMPAM 122
Query 1128 SAGIFGAKPLQSLQVC 1143
AG+ G + +
Sbjct 123 GAGVGGLSVAEVAREA 138
>sp|Q68772|RPOA_SHFV Replicase polyprotein 1ab OS=Simian hemorrhagic
fever virus OX=38143 GN=rep PE=2 SV=4
Length=3595
Score = 71.6 bits (174), Expect = 4e-10, Method: Composition-based stats.
Identities = 104/562 (19%), Positives = 188/562 (33%), Gaps = 111/562 (20%)
Query 4810 FFAQDG--NAAISDYDYYRYNLPTMCDIRQLLFVVEV----VDKYFDCYDGGCINANQVI 4863
++ Q G AA+ D + + L V + Y + +N
Sbjct 2333 YYTQHGCEAAALQDLKKFNLSTQGFILPEVLNIVRNYLLGTIGYRPAIYKPSTVPSND-- 2390
Query 4864 VNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRA 4923
+ N + ++ D D L V T+T + LK +K +
Sbjct 2391 -------SHAGINGLSFSTKTLQALP--DIDELCEKAIAEVWQTVTPVTLKKQFCSKAKT 2441
Query 4924 RTVAGVSICSTMTNRQFHQKLLKSI-AATRGATVVIGTSKFYGGWHNMLKTVYSDVETPH 4982
RT+ G + +++ R + + A + + + +G SKF D T
Sbjct 2442 RTILGTNAMASLALRALLSGVTQGFQLAGKNSPICLGKSKF-------------DPCTFE 2488
Query 4983 LMG----WDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMC 5038
+ G D CDR+ P ++R A+ +L C + Y + N C ++++
Sbjct 2489 VKGRCLETDLASCDRSTPAIVRHFATKLLFEM--ACAERALPLY-VVNCCH----DLIVT 2541
Query 5039 GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYE 5098
S K GG SSGD T+ AN+++++ V V LL +G+ ++ ++ L +L
Sbjct 2542 QTSAATKRGGLSSGDPVTSIANTIYSLVLYVQHMVLTLLE-NGHPLS---LKFLSGKL-- 2595
Query 5099 CLYRNRDVDHEFVDEFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKA---VL 5155
+ L K + ++ SDD ++ S+ + NF+ L
Sbjct 2596 ---------------NFQDLYKLQAFIVYSDDLILLNESD--------DLPNFERWVPHL 2632
Query 5156 YYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDD 5215
+ K ++ E+ +H LV P R+L A + +
Sbjct 2633 ELALGFKVDPKKTVITSNPGFLGCEY--RHGWLV-----------PQKQRVLAALAYHVN 2679
Query 5216 IVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVM 5275
+ ++ DA L+ + D+ RK D YS
Sbjct 2680 AKDVHTYYI--NATAILNDASALSAFEPDWFDDLVIGLADCARK----------DGYSFP 2727
Query 5276 LTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHV 5335
+ Y+ +Q C ++T+ CG LC C + H
Sbjct 2728 GPAAFREFFSRVSGYQFEGKE---VQVCSIC-CSTARTTSLCG-----MALCDFCAHRHY 2778
Query 5336 ISTSHKLVLSVNP-YVCNAPGC 5356
H VLS +V + C
Sbjct 2779 HPGCH--VLSSFCKHVIGSNTC 2798
Score = 70.9 bits (172), Expect = 6e-10, Method: Composition-based stats.
Identities = 44/210 (21%), Positives = 79/210 (38%), Gaps = 38/210 (18%)
Query 6567 RNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQS 6626
N ++++ + L+ A V +G T + K +DG + ++ ++
Sbjct 3243 PNRLVVSATRLSPLSHPAVCAGYYVGDSLFVGTPNVTSYWLTKFLDGRAVPMEDSVYSTG 3302
Query 6627 RDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKR 6686
R D D+L+ A +F ++ H GD +GG H +
Sbjct 3303 RFEMDI-------RDYLDSAERDFAAKH-------PHAFIGDTKGTTVGGCHHITSQY-- 3346
Query 6687 SQDSPLKLEDFIPMDSTVKNYFITDAQTG-SSKCVCSVIDLLLDDF--VEIIKSQDLSVI 6743
L +P DS VK + ++ G + K +C+V D+ L +Q
Sbjct 3347 -------LPHVLPADSVVK---VGVSKPGVAHKALCTVTDIYLPMLGSYTSPPTQ----- 3391
Query 6744 SKVVKVTIDYAEISFMLWCKDGHVETFYPK 6773
SKV KV +D+ M+W +T Y +
Sbjct 3392 SKVYKVNVDHKACKLMVWRD----QTMYFQ 3417
Score = 53.5 bits (127), Expect = 1e-04, Method: Composition-based stats.
Identities = 67/344 (19%), Positives = 107/344 (31%), Gaps = 72/344 (21%)
Query 5580 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA 5639
+ GPPG+GK+ F L +VY +H ++ + +P
Sbjct 2894 FVVGPPGSGKTTFISNLL---DDDAVVYC-PTHVSL------IAYSKSLPAARFSVPRGQ 2943
Query 5640 RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY 5699
+ ++ Q + +P DE A +D+ + ++
Sbjct 2944 DPAEYGTPALSGPTLQ--LLSAGYVPGAKH---YLDEACYANPFDVFKLLSK---TPITA 2995
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
IGDPAQL T + + V LMK L R I
Sbjct 2996 IGDPAQL-------TPVGFDTPLY--VFELMK----KNALHAIYRFGQNI---------- 3032
Query 5760 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5819
+ + +++ Q F T+ + ++PY+
Sbjct 3033 -----------------CNAIQPCYSTKLVSQRQGDTEVIFQTKFAP--RGKVLTPYHRD 3073
Query 5820 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCIMSD 5879
A+ T+DSSQGS YD V T T S + R V ITRA+ +
Sbjct 3074 RVGAA-------VTIDSSQGSTYDVV--TLYLPTKGSLTLARGLVGITRARERLYVYDPH 3124
Query 5880 RDL--YDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLH 5921
L Y LQ +S I R + + + L C
Sbjct 3125 HQLAKYFNLQPSSTTI-RPHAVVIDGKARVMLSDKCYAAPEDFP 3167
>sp|Q8QL53|POLN_SLDV Polyprotein P1234 OS=Sleeping disease virus
OX=78540 PE=3 SV=1
Length=2593
Score = 71.2 bits (173), Expect = 5e-10, Method: Composition-based stats.
Identities = 42/164 (26%), Positives = 61/164 (37%), Gaps = 26/164 (16%)
Query 1025 KEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLS 1084
K +A V+VNAAN + + G GV GAL A A NG + G + L+
Sbjct 1429 KNIITAEEEVLVNAANSNGRPGDGVCGALYGAFGDAF---------PNGAIGAGNAVLVR 1479
Query 1085 GHNLAKKCLHVVGPNLNAGEDI---QLLKAAYEN------FNSQDILLAPLLSAGIFG-- 1133
G L +H G + ++ + L+AAY N PLLS IF
Sbjct 1480 G--LEATIIHAAGADFREVDEETGARQLRAAYRAAATLVTANGITSAAIPLLSTHIFSNG 1537
Query 1134 -AKPLQSLQVCV---QTVRTQVYIAVNDKALYEQVVMDYLDNLK 1173
+ QS V T V I + ++ D+ +
Sbjct 1538 RNRLEQSFGALVEAFDTTECDVTIYCLANNMAARIQQLIDDHAR 1581
Score = 40.8 bits (94), Expect = 0.76, Method: Composition-based stats.
Identities = 23/106 (22%), Positives = 34/106 (32%), Gaps = 11/106 (10%)
Query 5666 ETTADIVVFDEISMATNYDLSVVNARLRAK-HYVYIGDPAQLPAPRTLLTKGTLEPEYFN 5724
D + DE + L + A +R V GDP Q+ L + E +
Sbjct 807 RGAVDTLYVDEAYACHSGTLLALIAAVRPTGKVVLCGDPKQVGCVNQLQMRMHYNHEISD 866
Query 5725 SVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSA 5770
V R RRC + VS L Y+ ++K
Sbjct 867 RVLRK----------NISRRCTHTLTAIVSNLNYEGRMKTTNPCKK 902
>sp|Q86500|POLN_RUBVM Non-structural polyprotein p200 OS=Rubella
virus (strain M33) OX=11043 PE=1 SV=2
Length=2116
Score = 70.9 bits (172), Expect = 5e-10, Method: Composition-based stats.
Identities = 41/182 (23%), Positives = 64/182 (35%), Gaps = 20/182 (11%)
Query 970 TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQS 1029
T + L+ E S + P+ + + Y + V ++ DI+
Sbjct 775 TAEPADRARHAELEVVYEPSGPPTSTKADPDSDIVE--SYARAAGPVHLRVRDIMDPPPG 832
Query 1030 ANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA 1089
V+VNAAN L G GV GA+ A+ + P +G + GH
Sbjct 833 CK--VVVNAANEGLLAGSGVCGAIFANATAALAADCRRLA----PCPIGEAVATPGHGCG 886
Query 1090 -KKCLHVVGPN-----LNAGEDIQLLKAAYENFNSQDILLA------PLLSAGIFGAKPL 1137
+H V P E LL+ AY + + PLL AG++G
Sbjct 887 YTHIIHAVAPRRPRDPAALEEGEALLERAYRSIVALAAARRWARVACPLLGAGVYGWSAA 946
Query 1138 QS 1139
+S
Sbjct 947 ES 948
>sp|Q8JJX1|POLN_SPDV Polyprotein P1234 OS=Salmon pancreas disease
virus OX=84589 PE=3 SV=1
Length=2601
Score = 70.1 bits (170), Expect = 9e-10, Method: Composition-based stats.
Identities = 38/142 (27%), Positives = 53/142 (37%), Gaps = 26/142 (18%)
Query 1029 SANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL 1088
+A V+VNAAN + + G GV GAL A A NG + G + L+ G L
Sbjct 1434 TAEEEVLVNAANSNGRPGDGVCGALYGAFGDAF---------PNGAIGAGNAVLVRG--L 1482
Query 1089 AKKCLHVVGPNLNAGEDI---QLLKAAYEN------FNSQDILLAPLLSAGIFG------ 1133
+H G + ++ + L+AAY N PLLS IF
Sbjct 1483 EATIIHAAGADFREVDEETGARQLRAAYRAAATLVTANGITSAAIPLLSTHIFSNGRNRL 1542
Query 1134 AKPLQSLQVCVQTVRTQVYIAV 1155
+ +L T V I
Sbjct 1543 EQSFSALVEAFDTTECDVTIYC 1564
Score = 38.9 bits (89), Expect = 2.9, Method: Composition-based stats.
Identities = 42/208 (20%), Positives = 66/208 (32%), Gaps = 39/208 (19%)
Query 5666 ETTADIVVFDEISMATNYDLSVVNARLRAK-HYVYIGDPAQLPAPRTLLTKGTLEPEYFN 5724
+ + DE + L + A +R V GDP Q+ L + E +
Sbjct 808 RGAVNTLYVDEAYACHSGTLLALIAAVRPTGKVVLCGDPKQVGCVNQLQMRMHYNHEISD 867
Query 5725 SVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHD 5784
V R RRC + VS L Y+ ++K K + D
Sbjct 868 RVLRK----------NISRRCTHTLTAIVSNLNYEGRMKTTNP---------CKKPVLID 908
Query 5785 VSSAINRPQIGVVREFLTRNPAW-RKAVFISPYNSQNAVASKILGLPTQTVDSSQG--SE 5841
+ + + +V LT W + F+ P+N T +SQG E
Sbjct 909 TTGSTKPDKEALV---LTCFRGWVKDLKFLYPHN------------ELMTAAASQGLTRE 953
Query 5842 YDYVIFT-QTTETAHSCNVNRFNVAITR 5868
Y + TT + V +TR
Sbjct 954 KVYAVRCRVTTNPLYEPTSEHITVLLTR 981
>sp|Q9JGL0|POLN_SAGV Polyprotein P1234 OS=Sagiyama virus OX=59303
PE=3 SV=3
Length=2467
Score = 69.7 bits (169), Expect = 1e-09, Method: Composition-based stats.
Identities = 38/181 (21%), Positives = 63/181 (35%), Gaps = 28/181 (15%)
Query 1031 NPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAK 1090
+VNAAN GV A+ K + VG + ++ +
Sbjct 1347 GEEAVVNAANAKGTVSDGVCRAVAKKWPSSF---------KGAATPVGTAKMIRADGM-- 1395
Query 1091 KCLHVVGPNLNAGEDIQ---LLKAAYENF------NSQDILLAPLLSAGIFGA------K 1135
+H VGPN + + + L AAY N+ + PLLS G F +
Sbjct 1396 TVIHAVGPNFSTVTEAEGDRELAAAYRAVASIISTNNIKSVAVPLLSTGTFSGGKDRVMQ 1455
Query 1136 PLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEK 1195
L L + V I DK +E+ + + +D +E ++ T+ +
Sbjct 1456 SLNHLFTALDATDADVVIYCRDKN-WEKKIQEAIDRRTA-IELVSEDVTLETDLVRVHPD 1513
Query 1196 S 1196
S
Sbjct 1514 S 1514
>sp|Q5Y389|POLN_GETV Polyprotein P1234 OS=Getah virus OX=59300
PE=1 SV=3
Length=2467
Score = 69.7 bits (169), Expect = 1e-09, Method: Composition-based stats.
Identities = 38/181 (21%), Positives = 64/181 (35%), Gaps = 28/181 (15%)
Query 1031 NPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAK 1090
+ +VNAAN GV A+ K + VG + ++ +
Sbjct 1347 SEEAVVNAANAKGTVSDGVCRAVAKKWPSSF---------KGAATPVGTAKMIRADGM-- 1395
Query 1091 KCLHVVGPNLNAGEDIQ---LLKAAYENF------NSQDILLAPLLSAGIFGA------K 1135
+H VGPN + + + L AAY N+ + PLLS G F +
Sbjct 1396 TVIHAVGPNFSTVTEAEGDRELAAAYRAVASIISTNNIKSVAVPLLSTGTFSGGKDRVMQ 1455
Query 1136 PLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEK 1195
L L + V I DK +E+ + + +D +E ++ T+ +
Sbjct 1456 SLNHLFTALDATDADVVIYCRDKN-WEKKIQEAIDRRTA-IELVSEDVTLETDLVRVHPD 1513
Query 1196 S 1196
S
Sbjct 1514 S 1514
>sp|A0MD28|RPOA_PRRSS Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (isolate Pig/United
States/SD 01-08/2001) OX=857306 PE=1 SV=2
Length=3838
Score = 68.9 bits (167), Expect = 2e-09, Method: Composition-based stats.
Identities = 80/436 (18%), Positives = 150/436 (34%), Gaps = 68/436 (16%)
Query 4817 AAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFN 4876
AA D Y + L V + + G + K++ N
Sbjct 2617 AAAEDLQKYDLSTQGFVLPGVLRLVRRFIFGHI-----GKAPPLFLPSTYPAKNSMAGIN 2671
Query 4877 KWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMT 4936
G+ D S + D + A + T+T LK +K + RT+ G + +
Sbjct 2672 --GQRFPTKDVQSIPEIDEMCARAVKENWQTVTPCTLKKQYCSKPKTRTILGTNNFIALA 2729
Query 4937 NRQFHQKLLKSIAATR-GATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAM 4995
+R + ++ + + +G +KF K ++ V L D CDR+
Sbjct 2730 HRSALSGVTQAFMKKAWKSPIALGKNKF--------KELHCTVAGRCL-EADLASCDRST 2780
Query 4996 PNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDAT 5055
P ++R + +L C + + N C ++V + K GG SSGD
Sbjct 2781 PAIVRWFVANLLYEL-AGCEEYLPSY--VLNCCH----DLVATQDGAFTKRGGLSSGDPV 2833
Query 5056 TAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEF- 5114
T+ +N+V+++ QH + L ++ +F++E
Sbjct 2834 TSVSNTVYSLIIY-----------------------AQHMVLSALKMGHEIGLKFLEEQL 2870
Query 5115 -YAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETD 5173
+ L + M++ SDD V+ YA + + + L K T
Sbjct 2871 KFEDLLEIQPMLVYSDDLVL-----YAERPTFPNYHWWVEHLDLMLGFRTDPKK----TV 2921
Query 5174 LTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAI 5233
+T P S ++ G V P+ RIL A + + + + ++ +
Sbjct 2922 ITDKP----SFLGCRIEAGRQLV----PNRDRILAALAY--HMKAQNASEYYASAAAILM 2971
Query 5234 DAYPLTKHPNQEYADV 5249
D+ H + Y D+
Sbjct 2972 DSCACIDHDPEWYEDL 2987
Score = 61.2 bits (147), Expect = 5e-07, Method: Composition-based stats.
Identities = 70/399 (18%), Positives = 121/399 (30%), Gaps = 79/399 (20%)
Query 5580 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKA-LKYLPIDKCSRIIPAR 5638
+ GPPG+GK+ + L ++YT +H + + + I S +
Sbjct 3166 FIVGPPGSGKTTW---LLSQVQDDDVIYT-PTHQTMFDIVSALKVCRYSIPGASGL---- 3217
Query 5639 ARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYV 5698
F + +V + + DE + D + L V
Sbjct 3218 -------PFPPPARSGPWVRLVASGHVPGRTSYL--DEAGYCNHLD---ILRLLSKTPLV 3265
Query 5699 YIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVY 5758
+GD QL P F+S C + + P L T R I + Y
Sbjct 3266 CLGDLQQL------------HPVGFDSYCYVFDQM-PQKQLTTIYRFGPNICAAIQP-CY 3311
Query 5759 DNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV--FISPY 5816
KL++ + F W A ++PY
Sbjct 3312 REKLESKARNTRVVF-------------------------------TTWPVAFGQVLTPY 3340
Query 5817 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCI 5876
+ +G T+DSSQG+ +D I T + S N +R VAITRA+ G+
Sbjct 3341 HKDR------IGSAI-TIDSSQGATFD--IVTLHLPSPKSLNKSRALVAITRARHGLFIY 3391
Query 5877 MSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFK 5936
L + E N+ + +++ L D + P+ V
Sbjct 3392 DPHNQLQEFFNLIP-ERTDCNLVFSRGDDLVVLSADNAVTTVAKALGTGPSRFRVSDPRC 3450
Query 5937 TEGLCVDIPGIPKDM-TYRRLISMMGFKMNYQVNGYPNM 5974
L + ++ +GF + + +
Sbjct 3451 KSLLAACSASLEGSCMPLPQVAHNLGFYFSPDSPAFAPL 3489
Score = 54.7 bits (130), Expect = 5e-05, Method: Composition-based stats.
Identities = 44/229 (19%), Positives = 79/229 (34%), Gaps = 39/229 (17%)
Query 6595 TLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRY 6654
T +G + + G Q LPET + R D ++L+ A +E
Sbjct 3538 TFLGTPGVVSYYLTLYIRGEPQALPETLVSTGRIATDC-------REYLDAAEEE----- 3585
Query 6655 KLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQT 6714
H GD +GG H + L +P DS +
Sbjct 3586 --AAKELPHAFIGDVKGTTVGGCHHITSKY---------LPRTLPKDSV--AVVGVSSPG 3632
Query 6715 GSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKL 6774
++K +C++ D+ L + ++ + SK K+ +D+ ++ M+W T Y +L
Sbjct 3633 RAAKAMCTLTDVYLPELRPYLQPE---TASKCWKLKLDFRDVRLMVW----KGATAYFQL 3685
Query 6775 QASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYT 6823
+ G+ L R + D Y + + P V + T
Sbjct 3686 E-------GLTWSALPDYARFIQLPKDAVVYIDPCIGPATANRKVVRTT 3727
>sp|Q06502|RPOA_LDVC Replicase polyprotein 1ab OS=Lactate dehydrogenase
elevating virus (strain C) OX=300015 GN=rep PE=3 SV=2
Length=3637
Score = 68.9 bits (167), Expect = 2e-09, Method: Composition-based stats.
Identities = 92/545 (17%), Positives = 167/545 (31%), Gaps = 97/545 (18%)
Query 4818 AISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNK 4877
A D + + L V + + + + + AG N+
Sbjct 2463 AECDLQKFDLSRQGFVLPGVLYMVRRYLCRLVGIRRRLFLPSTY---PAKNSMAGINGNR 2519
Query 4878 WGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTN 4937
+ + S+ D DAL + T+T LK +K + RT+ G + +
Sbjct 2520 FPT----HVVQSHPDIDALCERACKEHWQTVTPCTLKKQYCSKAKTRTILGTNNFVALGL 2575
Query 4938 RQFHQKLLKS-IAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMP 4996
R + + + G+ + +G +KF T + + D CDR+ P
Sbjct 2576 RSALSGVTQGFMRKGIGSPICLGKNKF---------TPLPTKVSGRCLEADLASCDRSTP 2626
Query 4997 NMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATT 5056
++R + +L + + N C +S M C + K GG SSGD T
Sbjct 2627 AIIRWFTTNLLFELAGP-EEWIPSY--VLNCCHDAVSTMSGC----FDKRGGLSSGDPVT 2679
Query 5057 AYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYA 5116
+ +N+V+++ V + G+K+ ++R+ E
Sbjct 2680 SVSNTVYSLVIYAQHMVLSAFRC-GHKVGGLFLRD-----------------SLEMEQLF 2721
Query 5117 YLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETDLTK 5176
L+ +++ SDD VV Y+ + F L +K +D
Sbjct 2722 ELQP---LLVYSDD-VVLYDESSELPNYHF----FVDHLDLMLGFKTDRSKTVITSDPQF 2773
Query 5177 GPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAY 5236
+ ++ P RIL A + ++ +DA
Sbjct 2774 PGCRIAAGRVLV------------PQRDRILAALAYHMKASCVSDYFASA--AAILMDAC 2819
Query 5237 PLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTP 5296
+ Y D+ RK R+ P FY M+
Sbjct 2820 ACCDYDEDWYFDLVCGIADCARK--------------------EGFRFPGPSFYVDMWKR 2859
Query 5297 HTV--LQAVGACVLCNSQT--SLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCN 5352
+V + C C + + CG LC + H H V+ +
Sbjct 2860 LSVEEKKKCRTCAHCGAPSTLVSSCG-----LNLCDYHGHGH----PHCPVVLPCGHAVG 2910
Query 5353 APGCD 5357
+ CD
Sbjct 2911 SGVCD 2915
Score = 62.4 bits (150), Expect = 2e-07, Method: Composition-based stats.
Identities = 57/314 (18%), Positives = 93/314 (30%), Gaps = 71/314 (23%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5636
+ + G PGTGK+ + L ++YT +H + + + R P
Sbjct 3007 RSQFITGAPGTGKTTY---LLSVVRDDDVIYT-PTHRTMLDVVKAL-------GTCRFDP 3055
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
+ F + T +P + DE + D+ + ++
Sbjct 3056 PKDTPLEFPV--PSRTGPCVRLIRAGFIP---GRVSYLDEAAYCNPLDVLKILSK---TP 3107
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5756
V +GD QLP P F C + L R IV+
Sbjct 3108 LVCVGDLNQLP------------PVDFIGPCYAF-ALMLGRQLIEVFRFGPSIVN-PIKK 3153
Query 5757 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5816
Y +L + + +FL + ++PY
Sbjct 3154 FYREELVSRGPDTG---------------------------VKFLKSYQPY--GQVLTPY 3184
Query 5817 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCI 5876
+ + T+DSSQG YD + T S N R VAITRA+ +
Sbjct 3185 HRDRVDGA-------ITIDSSQGCTYDVITVYL--PTPKSLNSARALVAITRARFYVFVY 3235
Query 5877 MSDRDLYDKLQFTS 5890
L L +
Sbjct 3236 DPHNQLEQYLNMSE 3249
Score = 43.5 bits (101), Expect = 0.11, Method: Composition-based stats.
Identities = 36/190 (19%), Positives = 66/190 (35%), Gaps = 36/190 (19%)
Query 6605 FNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHI 6664
+ K + G LP++ + R + ++L+ EF R H
Sbjct 3378 YYLTKFLKGKPVPLPDSLMSTGRIALNV-------REYLDEKEMEFSSR-------CPHA 3423
Query 6665 VYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQTGSSKCVCSVI 6724
G+ +GG H + L + S VK ++K +C+V
Sbjct 3424 FIGEVKGSNVGGCHHVTSRY---------LPPVLVPGSVVK--IGVSCPGKAAKELCTVT 3472
Query 6725 DLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKLQASQAWQPGV 6784
D+ L E+ + S K+ +D+ + M+W KD T Y + +P
Sbjct 3473 DVYLP---ELDPYLNPPTKSMDYKLLVDFQPVKLMVW-KD---ATAY----FHEGIRPME 3521
Query 6785 AMPNLYKMQR 6794
+M K+ +
Sbjct 3522 SMSRFLKVPQ 3531
>sp|Q04561|RPOA_PRRSL Replicase polyprotein 1ab OS=Porcine reproductive
and respiratory syndrome virus (strain Lelystad) OX=11049
GN=rep PE=1 SV=3
Length=3855
Score = 68.5 bits (166), Expect = 3e-09, Method: Composition-based stats.
Identities = 80/436 (18%), Positives = 150/436 (34%), Gaps = 68/436 (16%)
Query 4817 AAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFN 4876
AA D Y + L V + + G + K++ N
Sbjct 2634 AAAEDLQKYDLSTQGFVLPGVLRLVRRFIFGHI-----GKAPPLFLPSTYPAKNSMAGIN 2688
Query 4877 KWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMT 4936
G+ D S + D + A + T+T LK +K + RT+ G + +
Sbjct 2689 --GQRFPTKDVQSIPEIDEMCARAVKENWQTVTPCTLKKQYCSKPKTRTILGTNNFIALA 2746
Query 4937 NRQFHQKLLKSIAATR-GATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAM 4995
+R + ++ + + +G +KF K ++ V L D CDR+
Sbjct 2747 HRSALSGVTQAFMKKAWKSPIALGKNKF--------KELHCTVAGRCL-EADLASCDRST 2797
Query 4996 PNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDAT 5055
P ++R + +L C + + N C ++V + K GG SSGD
Sbjct 2798 PAIVRWFVANLLYEL-AGCEEYLPSY--VLNCCH----DLVATQDGAFTKRGGLSSGDPV 2850
Query 5056 TAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEF- 5114
T+ +N+V+++ QH + L ++ +F++E
Sbjct 2851 TSVSNTVYSLVIY-----------------------AQHMVLSALKMGHEIGLKFLEEQL 2887
Query 5115 -YAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTETD 5173
+ L + M++ SDD V+ YA + + + L K T
Sbjct 2888 KFEDLLEIQPMLVYSDDLVL-----YAERPTFPNYHWWVEHLDLMLGFRTDPKK----TV 2938
Query 5174 LTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAI 5233
+T P S ++ G V P+ RIL A + + + + ++ +
Sbjct 2939 ITDKP----SFLGCRIEAGRQLV----PNRDRILAALAY--HMKAQNASEYYASAAAILM 2988
Query 5234 DAYPLTKHPNQEYADV 5249
D+ H + Y D+
Sbjct 2989 DSCACIDHDPEWYEDL 3004
Score = 59.7 bits (143), Expect = 1e-06, Method: Composition-based stats.
Identities = 70/399 (18%), Positives = 122/399 (31%), Gaps = 79/399 (20%)
Query 5580 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKA-LKYLPIDKCSRIIPAR 5638
+ GPPG+GK+ + L ++YT +H + + + I S +
Sbjct 3183 FIVGPPGSGKTTW---LLSQVQDDDVIYT-PTHQTMFDIVSALKVCRYSIPGASGL---- 3234
Query 5639 ARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYV 5698
F + +V + + DE + D + L V
Sbjct 3235 -------PFPPPARSGPWVRLIASG--HVPGRVSYLDEAGYCNHLD---ILRLLSKTPLV 3282
Query 5699 YIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVY 5758
+GD QL P F+S C + + P L T R I + Y
Sbjct 3283 CLGDLQQL------------HPVGFDSYCYVFDQM-PQKQLTTIYRFGPNICAAIQP-CY 3328
Query 5759 DNKLKAHKDKSAQCF--KMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5816
KL++ + F + G + ++PY
Sbjct 3329 REKLESKARNTRVVFTTRPVAFGQV-------------------------------LTPY 3357
Query 5817 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCI 5876
+ +G T+DSSQG+ +D I T + S N +R VAITRA+ G+
Sbjct 3358 HKDR------IGSAI-TIDSSQGATFD--IVTLHLPSPKSLNKSRALVAITRARHGLFIY 3408
Query 5877 MSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFK 5936
L + T E N+ + + + L D + P+ V
Sbjct 3409 DPHNQLQEFFNLTP-ERTDCNLVFSRGDELVVLNADNAVTTVAKALETGPSRFRVSDPRC 3467
Query 5937 TEGLCVDIPGIPKDM-TYRRLISMMGFKMNYQVNGYPNM 5974
L + ++ +GF + + +
Sbjct 3468 KSLLAACSASLEGSCMPLPQVAHNLGFYFSPDSPTFAPL 3506
Score = 56.2 bits (134), Expect = 2e-05, Method: Composition-based stats.
Identities = 45/229 (20%), Positives = 79/229 (34%), Gaps = 39/229 (17%)
Query 6595 TLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDEFIQRY 6654
T +G + + G Q LPET + R D ++L+ A +E
Sbjct 3555 TFLGTPGVVSYYLTLYIRGEPQALPETLVSTGRIATDC-------REYLDAAEEE----- 3602
Query 6655 KLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFITDAQT 6714
H GD +GG H + L +P DS +
Sbjct 3603 --AAKELPHAFIGDVKGTTVGGCHHITSKY---------LPRSLPKDSV--AVVGVSSPG 3649
Query 6715 GSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVETFYPKL 6774
++K VC++ D+ L + ++ + SK K+ +D+ ++ M+W T Y +L
Sbjct 3650 RAAKAVCTLTDVYLPELRPYLQPE---TASKCWKLKLDFRDVRLMVW----KGATAYFQL 3702
Query 6775 QASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYT 6823
+ G+ L R + D Y + + P V + T
Sbjct 3703 E-------GLTWSALPDYARFIQLPKDAVVYIDPCIGPATANRKVVRTT 3744
>sp|Q5XGM5|GDAP2_XENLA Ganglioside-induced differentiation-associated
protein 2 OS=Xenopus laevis OX=8355 PE=2 SV=1
Length=496
Score = 66.2 bits (160), Expect = 7e-09, Method: Composition-based stats.
Identities = 46/245 (19%), Positives = 85/245 (35%), Gaps = 35/245 (14%)
Query 973 VEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANP 1032
V EE ED D + P P + + V + D+ N
Sbjct 22 VSNEEGEDVPDGGRKDVPDGGSHSPFPYRK--------DINEKVILWKGDVA----LLNC 69
Query 1033 MVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKK 1091
+VN +N L V+ ++ + + + +E KL G G + L G NL A+
Sbjct 70 TALVNTSNETLTDKNPVSDSIFRYSGPELLEE---MQKLKG-CRTGEAKLTKGFNLAARY 125
Query 1092 CLHVVGPNLNAG---EDIQLLKAAYENFNSQ------DILLAPLLSAGIFGAKPLQSLQV 1142
+H VGP L + Y N + +++ + +
Sbjct 126 IIHTVGPKYKTKYRTAAESSLYSCYRNVLQLAKEQGMASVGFCVITTQKRCYPLDDATHI 185
Query 1143 CVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDS--KTEEKSVVQK 1200
++TVR ++ V+ +AL + V + E + P + E++S++
Sbjct 186 ALRTVRR--FLEVHGQALEKVVFAVTEEE-----EGTYRRLLPLYFPRSLEEEQRSILLL 238
Query 1201 PVDVK 1205
P D+
Sbjct 239 PQDIG 243
>sp|Q83017|RPOA_LDVP Replicase polyprotein 1ab OS=Lactate dehydrogenase
elevating virus (strain Plagemann) OX=300016 GN=rep
PE=1 SV=2
Length=3616
Score = 67.0 bits (162), Expect = 1e-08, Method: Composition-based stats.
Identities = 64/314 (20%), Positives = 100/314 (32%), Gaps = 71/314 (23%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5636
+ + G PGTGK+ + L ++YT +H + + KALK D P
Sbjct 2986 RSQFVTGAPGTGKTTY---LLSVVRDDDVIYT-PTHRTMLDV-VKALKVCRFD------P 3034
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
+ F T +P + DE + D+ V ++
Sbjct 3035 PKDTPLEFPV--PGRTGPTVRLIGAGFVP---GRVSYLDEAAYCNPLDVLKVLSK---TP 3086
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5756
V +GD QLP P FN C ++ P L R +V+++
Sbjct 3087 LVCVGDLNQLP------------PVGFNGPCFAF-SLMPGRQLIEVFRFGPAVVNSI-KK 3132
Query 5757 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5816
Y +L + +FL + + ++PY
Sbjct 3133 FYKEELVPRGPDTG---------------------------VKFLKQYQPY--GQVLTPY 3163
Query 5817 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCI 5876
+ + T+DSSQG YD V T S N R VA+TRA+ +
Sbjct 3164 HRDRVDGA-------ITIDSSQGCTYDVVTVYL--PTPKSLNSARALVALTRARHYVFIY 3214
Query 5877 MSDRDLYDKLQFTS 5890
L LQ
Sbjct 3215 DPYDQLQQYLQVFE 3228
Score = 64.7 bits (156), Expect = 5e-08, Method: Composition-based stats.
Identities = 103/588 (18%), Positives = 180/588 (31%), Gaps = 100/588 (17%)
Query 4814 DGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGF 4873
+AA D + + L V + + + + K++
Sbjct 2438 CASAAEKDLQKFDLSRQGFVLPGVLYMVRRYLSRLIGVRRRLFMPSTYPA-----KNSMA 2492
Query 4874 PFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICS 4933
N G+ L + S+ D DAL T+T LK +K++ RT+ G +
Sbjct 2493 GING-GRFPLTWLQ-SHPDIDALCKRACEEHWQTVTPCTLKKQYCSKSKTRTILGTNNFV 2550
Query 4934 TMTNRQFHQKLLKS-IAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCD 4992
+ R + + + G + +G +KF T + D CD
Sbjct 2551 ALGLRSALSGVTQGFMRKGIGTPICLGKNKF---------TPLPVRIGGRCLEADLASCD 2601
Query 4993 RAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSG 5052
R+ P ++R + +L + + N C V+S M C + K GG SSG
Sbjct 2602 RSTPAIIRWFTTNLLFELAGA-EEWIPSY--VLNCCHDVVSTMSGC----FDKRGGLSSG 2654
Query 5053 DATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVD 5112
D T+ +N+V+++ V + G+KI ++++
Sbjct 2655 DPVTSISNTVYSLIIYAQHMVLSAFRC-GHKIGGLFLQD-----------------SLEM 2696
Query 5113 EFYAYLRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAKCWTET 5172
E L+ +++ SDD VV YN + F L +K T
Sbjct 2697 EQLFELQP---LLVYSDD-VVFYNESDELPNYHF----FVDHLDLMLGFKTDRSKT-VIT 2747
Query 5173 DLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLA 5232
K P S +LV P RI+ A + ++
Sbjct 2748 SEPKLPGCRISGGRVLV-----------PQRDRIVAALAYQMKASCVGEYFASA--AAIL 2794
Query 5233 IDAYPLTKHPNQEYADVFHLYLQYIRK--LHDELTGHMLDMYSVMLTNDNTSRYWEPEFY 5290
+DA H Y D+ + LDM++ + +
Sbjct 2795 MDACACCDHDESWYFDLVCGIAECAGSPWFRFPGPSFFLDMWNRLSAEEK---------- 2844
Query 5291 EAMYTPHTVLQAVGACVLCNSQT--SLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNP 5348
+ C C + CG LC + H H V+
Sbjct 2845 ----------KKCRTCAHCGAPATLVSSCG-----LNLCDYHGHGH----PHCPVVLPCG 2885
Query 5349 YVCNAPGCDVTDVTQLYLGG---MSYYCKSHKPPISFPLCANGQVFGL 5393
+ + C+ + + L + C + PP L N +V L
Sbjct 2886 HAVGSGVCEQCSSSAMNLNTELDILLMCVPYHPPKVELLSVNDKVSSL 2933
Score = 40.4 bits (93), Expect = 0.82, Method: Composition-based stats.
Identities = 36/205 (18%), Positives = 69/205 (34%), Gaps = 36/205 (18%)
Query 6590 SVNGVTLIGESVKTQFNYFKKVDGIIQQLPETYFTQSRDLEDFKPRSQMETDFLELAMDE 6649
V +G + K + G LP++ + R + ++L+ E
Sbjct 3342 YVGPSIFLGVPGVVSYYLTKYLKGESVPLPDSIMSTGRIRLNV-------REYLDENEIE 3394
Query 6650 FIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAKRSQDSPLKLEDFIPMDSTVKNYFI 6709
F ++ G+ +GG H + L + S VK
Sbjct 3395 FAKK-------CPQPFIGEVKGSNVGGCHHVTSRF---------LPPVLVPGSVVK--VG 3436
Query 6710 TDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVISKVVKVTIDYAEISFMLWCKDGHVET 6769
++K +C+V D+ L + + S+ K++ +D+ + M+W KD T
Sbjct 3437 VSCPGKAAKGLCTVTDVYLPELDSYLHPPSKSMDYKLL---VDFQPVKLMVW-KD---AT 3489
Query 6770 FYPKLQASQAWQPGVAMPNLYKMQR 6794
Y + +P AM K+
Sbjct 3490 AY----FHEGIRPMEAMSRFLKVPE 3510
>sp|P19811|RPOA_EAVBU Replicase polyprotein 1ab OS=Equine arteritis
virus (strain Bucyrus) OX=299386 GN=rep PE=1 SV=3
Length=3175
Score = 66.6 bits (161), Expect = 1e-08, Method: Composition-based stats.
Identities = 47/209 (22%), Positives = 85/209 (41%), Gaps = 37/209 (18%)
Query 6567 RNGVLITEGSVKGLTPSKGPAQASVNGVTLIGESV-KTQFNYFKKVDGIIQQLPETYFTQ 6625
N + IT V L+ K + + G ++ ++ T + + VDG + LP++ F+
Sbjct 2882 PNCLQITLQQVCELS--KPCSAGYMVGQSVFVQTPGVTSYWLTEWVDGKARALPDSLFSS 2939
Query 6626 SRDLEDFKPRSQMETDFLELAMDEFIQRYKLEGYAFEHIVYGDFSHGQLGGLHLMIGLAK 6685
R F+ S FL+ A ++F + H G+ + +GG H +
Sbjct 2940 GR----FETNS---RAFLDEAEEKFAAAH-------PHACLGEINKSTVGGSHFIFSQY- 2984
Query 6686 RSQDSPLKLEDFIPMDSTVKNYFITDAQTG-SSKCVCSVIDLLLDDFVEIIKSQDLSVIS 6744
L +P D+ + + G ++K CSV+D+ F + + L S
Sbjct 2985 --------LPPLLPADAVA---LVGASLAGKAAKAACSVVDVYAPSFEPYLHPETL---S 3030
Query 6745 KVVKVTIDYAEISFMLWCKDGHVETFYPK 6773
+V K+ ID+ M+W TFY +
Sbjct 3031 RVYKIMIDFKPCRLMVWRN----ATFYVQ 3055
Score = 53.9 bits (128), Expect = 9e-05, Method: Composition-based stats.
Identities = 74/410 (18%), Positives = 139/410 (34%), Gaps = 56/410 (14%)
Query 4761 RTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAIS 4820
R C +V TN +A T+ P + D + K + + F A
Sbjct 1915 RAGCEAVTDGTNVIA--TIGPFPEQQPIPD--IPKSVLDNCADISCDAFIAPAAETALCG 1970
Query 4821 DYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGK 4880
D + Y + V + + + D + V + + AG ++
Sbjct 1971 DLEKYNLSTQGFVLPSVFSMVRAYLKE--EIGDAPPLYLPST-VPSKNSQAGINGAEFPT 2027
Query 4881 ARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQF 4940
L SY D + + + ++ + T T K +K + R++ G + + R
Sbjct 2028 KSL----QSYCLIDDMVSQSMKSNLQTATMATCKRQYCSKYKIRSILGTNNYIGLGLRAC 2083
Query 4941 HQKLLKSI--AATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNM 4998
+ + A G+ + +G SKF + L D CDR+ P +
Sbjct 2084 LSGVTAAFQKAGKDGSPIYLGKSKF---------DPIPAPDKYCL-ETDLESCDRSTPAL 2133
Query 4999 LRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAY 5058
+R A+ ++ + C ++V+ G + K GG SSGD T+
Sbjct 2134 VRWFATNLIFELAGQ----PELVHSYVLNCCH---DLVVAGSVAFTKRGGLSSGDPITSI 2186
Query 5059 ANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEF-VDEFYAY 5117
+N+++++ + L +IA+KY+ D + + + Y
Sbjct 2187 SNTIYSLVLYTQHMLLCGLEGYFPEIAEKYL-----------------DGSLELRDMFKY 2229
Query 5118 LRKHFSMMILSDDAVVCYNSNYAAQGLVASIKNFKAVLYYQNNVFMSEAK 5167
+R + I SDD V+ Q AS + L + K
Sbjct 2230 VR----VYIYSDDVVL----TTPNQHYAASFDRWVPHLQALLGFKVDPKK 2271
Score = 50.8 bits (120), Expect = 6e-04, Method: Composition-based stats.
Identities = 65/339 (19%), Positives = 109/339 (32%), Gaps = 62/339 (18%)
Query 5552 GLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACS 5611
G + + + D V N ++GPPG+GK+ + L + + +
Sbjct 2497 GSHIAVPLQDTLKGVVVNKALKNAAASEYVEGPPGSGKTFHLVKDVLAVVGSATLVV-PT 2555
Query 5612 HAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADI 5671
HA++ K + ++P ++ + S V T
Sbjct 2556 HASMLDCINKLKQAG--ADPYFVVPKYTVLDFP---RPGSGNITVRLPQVGTSEGETF-- 2608
Query 5672 VVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMK 5731
DE++ + DL+ + + R K Y GD QL L +F S+
Sbjct 2609 --VDEVAYFSPVDLARILTQGRVKGY---GDLNQLGCVGPASVPRNLWLRHFVSLEP--- 2660
Query 5732 TIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINR 5791
L C R A + D + + + + + K+ +
Sbjct 2661 -------LRVCHRFGAAVCDLIKGIY------PYYEPAPHTTKVVF-------------- 2693
Query 5792 PQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTT 5851
NP + K V I+ Y+ GL +T+DS QG + V T
Sbjct 2694 ----------VPNPDFEKGVVITAYHKDR-------GLGHRTIDSIQGCTFPVV--TLRL 2734
Query 5852 ETAHSCNVNRFNVAITRAKIGILCIMSDRDLYDKLQFTS 5890
T S R VA+TRA + L L+FT
Sbjct 2735 PTPQSLTRPRAVVAVTRASQELYIYDPFDQLSGLLKFTK 2773
>sp|Q2KIX2|GDAP2_BOVIN Ganglioside-induced differentiation-associated
protein 2 OS=Bos taurus OX=9913 GN=GDAP2 PE=2 SV=1
Length=497
Score = 64.7 bits (156), Expect = 2e-08, Method: Composition-based stats.
Identities = 46/230 (20%), Positives = 83/230 (36%), Gaps = 26/230 (11%)
Query 980 DWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAA 1039
+ +D SEI E E + F + V + D+ N IVN +
Sbjct 21 NSCEDQLNASEIAAE-TYQEETIRSPFLYNKDINGKVVLWKGDVA----LLNCTAIVNTS 75
Query 1040 NIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGP 1098
N L V+ ++ +++ D KL G G + L G NL A+ +H VGP
Sbjct 76 NESLTDKNPVSESIFMLAGPDLKE---DLQKLRG-CRTGEAKLTKGFNLAARFIIHTVGP 131
Query 1099 NLNAG---EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
+ L + Y N S + ++++ G + + ++TVR
Sbjct 132 KYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRR 191
Query 1150 QVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQ 1199
++ ++ + L + V + EA Q+ P +E+S
Sbjct 192 --FLEIHGETLEKVVFA-----VSELEEATYQKLLPLYFPRSLKEESRSL 234
>sp|Q460N3|PAR15_HUMAN Protein mono-ADP-ribosyltransferase PARP15
OS=Homo sapiens OX=9606 GN=PARP15 PE=1 SV=2
Length=678
Score = 63.9 bits (154), Expect = 4e-08, Method: Composition-based stats.
Identities = 38/178 (21%), Positives = 66/178 (37%), Gaps = 15/178 (8%)
Query 1015 NVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGG-VAGALNKATNGAMQKESDDYIKLNG 1073
N+ + D++ VIVN+ ++L+ GGG ++ A + +QKE DD +
Sbjct 90 NLKLISGDVLYI----WADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDD-RRRET 144
Query 1074 PLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDI--QLLKAAYEN------FNSQDILLA 1124
VG + SG NL K LH V P N G + Q++ + S +
Sbjct 145 EEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSITF 204
Query 1125 PLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQE 1182
P++ G ++ + V + ++V N +A E
Sbjct 205 PMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAFLDE 262
>sp|P47386|Y140_MYCGE Uncharacterized ATP-dependent helicase MG140
OS=Mycoplasma genitalium (strain ATCC 33530 / DSM 19775
/ NCTC 10195 / G37) OX=243273 GN=MG140 PE=3 SV=1
Length=1113
Score = 64.3 bits (155), Expect = 5e-08, Method: Composition-based stats.
Identities = 56/277 (20%), Positives = 98/277 (35%), Gaps = 52/277 (19%)
Query 5652 TLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRT 5711
TLE T N D VV DE S + RA Y+ GD QL
Sbjct 681 TLESAATLTPNQ--RGLYDYVVIDEASQVFLERA--IPILFRADKYIIAGDTKQLKPANF 736
Query 5712 LLTKGTLEPE------------YFNSVCRLMKTIGPDMFLGTC-RRC-PAEIVDTVSALV 5757
++ + + + +S+ +K + L R A+++ + +
Sbjct 737 FQSRAEYDVDEEFEDGNIEAAVHSSSLLHFLKNRSRILTLLKFHYRSDSADLIAFTNNRI 796
Query 5758 YDNKL----KAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5813
YDN+L KA+ D+ G+ ++ + R + + + T N + I
Sbjct 797 YDNELIFMNKANADQRVFIVHDVIDGIWKNNRNLQEARDVVQRLEQLTTTNDYKKSLGVI 856
Query 5814 SPYNSQNAVASKIL----------------------GLPTQTVDSSQGSEYDYVIFTQTT 5851
+Q + ++ GL + +++ QG E D +IF+
Sbjct 857 CFNKNQADLIEYLIDKQNNPLLNEWRERQNDVGEYEGLFVKNIENVQGDERDIIIFSLGY 916
Query 5852 ETAHSC--------NVNRFNVAITRAKIGILCIMSDR 5880
+ + + NR NVAITRAK I ++R
Sbjct 917 DRSVNSYGPISKQGGENRLNVAITRAKQRIELFKTNR 953
>sp|Q66HX8|GDAP2_DANRE Ganglioside-induced differentiation-associated
protein 2 OS=Danio rerio OX=7955 GN=gdap2 PE=2 SV=1
Length=504
Score = 63.2 bits (152), Expect = 7e-08, Method: Composition-based stats.
Identities = 36/181 (20%), Positives = 66/181 (36%), Gaps = 14/181 (8%)
Query 979 EDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNA 1038
+D LD E E E E +N ++ K V + N IVN
Sbjct 26 QDELDGENHYEEEEEEEEDNLTNQLNSVNSPFTFRQDINNKIVLFNGDVALLNCTAIVNT 85
Query 1039 ANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVG 1097
+N L ++ ++++ ++ E +KL G G + + G +L A+ +H VG
Sbjct 86 SNETLTDKNPISDSIHRHAGPELRDE---LLKLKG-CRTGEAKMTEGFDLAARFIIHTVG 141
Query 1098 PNLNAG---EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVR 1148
P A L + Y N ++ + ++S + + ++TVR
Sbjct 142 PKYKAKYRTAAESSLYSCYRNVLQLAKEHAMVSVGFCVISTVKRAYPVEDATHIALRTVR 201
Query 1149 T 1149
Sbjct 202 R 202
>sp|Q66H63|GDAP2_RAT Ganglioside-induced differentiation-associated-protein
2 OS=Rattus norvegicus OX=10116 GN=Gdap2 PE=2
SV=1
Length=497
Score = 63.2 bits (152), Expect = 7e-08, Method: Composition-based stats.
Identities = 49/262 (19%), Positives = 91/262 (35%), Gaps = 33/262 (13%)
Query 956 DYQGLPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDN 1015
D G P +F V + E++ + + + +P F +
Sbjct 2 DPLGAPSQFVDVDTLVSWGDSYEDEVNSSDSTAEAFQEDSNRSP------FLYNRDINGK 55
Query 1016 VAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPL 1075
V + D+ N IVN +N L V+ ++ +++ D KL G
Sbjct 56 VVLWKGDVA----LLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKE---DLQKLKG-C 107
Query 1076 TVGGSCLLSGHNL-AKKCLHVVGPNLNAG---EDIQLLKAAYENF------NSQDILLAP 1125
G + L G NL A+ +H VGP + L + Y N S +
Sbjct 108 RTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFC 167
Query 1126 LLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPP 1185
++++ G + + ++TVR + I + + + + + EA Q+ P
Sbjct 168 VINSAKRGYPLEDATHIALRTVRRFLEI-------HGETIEKVVFAISELEEATYQKLLP 220
Query 1186 NTEDS--KTEEKSVVQKPVDVK 1205
K E +S+ P D+
Sbjct 221 LYFPRSLKEESQSLPSLPADIG 242
>sp|Q9NXN4|GDAP2_HUMAN Ganglioside-induced differentiation-associated
protein 2 OS=Homo sapiens OX=9606 GN=GDAP2 PE=1 SV=1
Length=497
Score = 62.8 bits (151), Expect = 8e-08, Method: Composition-based stats.
Identities = 48/240 (20%), Positives = 84/240 (35%), Gaps = 32/240 (13%)
Query 980 DWLDDTTEQSEIEPE--PEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVN 1037
D D S+ E E T P F + V + D+ N IVN
Sbjct 21 DSCQDELNSSDTTAEIFQEDTVRSP---FLYNKDVNGKVVLWKGDVA----LLNCTAIVN 73
Query 1038 AANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVV 1096
+N L V+ ++ +++ D KL G G + L G NL A+ +H V
Sbjct 74 TSNESLTDKNPVSESIFMLAGPDLKE---DLQKLKG-CRTGEAKLTKGFNLAARFIIHTV 129
Query 1097 GPNLNAG---EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCVQTV 1147
GP + L + Y N S + ++++ G + + ++TV
Sbjct 130 GPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTV 189
Query 1148 RTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDS--KTEEKSVVQKPVDVK 1205
R ++ ++ + + + V E Q+ P K E +S+ P D+
Sbjct 190 RR--FLEIHGETIEKVVFAVSDLE-----EGTYQKLLPLYFPRSLKEENRSLPYLPADIG 242
>sp|Q9DBL2|GDAP2_MOUSE Ganglioside-induced differentiation-associated
protein 2 OS=Mus musculus OX=10090 GN=Gdap2 PE=1 SV=1
Length=498
Score = 62.0 bits (149), Expect = 2e-07, Method: Composition-based stats.
Identities = 52/243 (21%), Positives = 87/243 (36%), Gaps = 35/243 (14%)
Query 975 EEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMV 1034
E+E D D T E + + P F + V + D+ N
Sbjct 23 YEDEVDCADSTAEAFQEDASRSP--------FVYSRDVNGKVVLWKGDVA----LLNCTA 70
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
IVN +N L V+ ++ +++ D KL G G + L G NL A+ +
Sbjct 71 IVNTSNESLTDKNPVSESIFMLAGPDLKE---DLQKLKG-CRTGEAKLTKGFNLAARFII 126
Query 1094 HVVGPNLNAG---EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCV 1144
H VGP + L + Y N S + ++++ G + + +
Sbjct 127 HTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIAL 186
Query 1145 QTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDS--KTEEKSVVQKPV 1202
+TVR + I + E+VV + EA Q+ P K E +S+ P
Sbjct 187 RTVRRFLEIHGENI---EKVVF----AVSELEEATYQKLLPLYFPRSLKEEIRSLPYLPA 239
Query 1203 DVK 1205
D+
Sbjct 240 DIG 242
>sp|Q5CZL1|GDAP2_XENTR Ganglioside-induced differentiation-associated
protein 2 OS=Xenopus tropicalis OX=8364 PE=2 SV=1
Length=496
Score = 61.6 bits (148), Expect = 2e-07, Method: Composition-based stats.
Identities = 43/238 (18%), Positives = 81/238 (34%), Gaps = 27/238 (11%)
Query 980 DWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAA 1039
D D E + + F + V + D+ + +A +VN +
Sbjct 21 DVRDGEGEDVPDGGRKDAPHGGLHSPFPYRNDINKKVILWRGDVALLSCTA----LVNTS 76
Query 1040 NIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCLHVVGP 1098
N L V+ ++ + + + S++ KL G G + L G NL A+ +H VGP
Sbjct 77 NETLTDKNPVSDSIFRYSGPEL---SEEMQKLKG-CRTGEAKLTKGFNLAARYIIHTVGP 132
Query 1099 NLNAG---EDIQLLKAAYENFNSQ------DILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
L + Y N + +++ P S + ++TVR
Sbjct 133 KYKTKYRTAAESSLYSCYRNVLQLAKEQGMASVGFCVIATQKRCYPPEDSTHIALRTVRR 192
Query 1150 QVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDS--KTEEKSVVQKPVDVK 1205
++ + AL + V E + P + E++S+ P D+
Sbjct 193 --FLEAHGAALEKVVFAVTEQE-----EGTYRRLLPLYFPRSLEEEQRSIPFLPQDIG 243
>sp|Q4R678|GDAP2_MACFA Ganglioside-induced differentiation-associated
protein 2 OS=Macaca fascicularis OX=9541 GN=GDAP2 PE=2
SV=1
Length=461
Score = 60.8 bits (146), Expect = 3e-07, Method: Composition-based stats.
Identities = 40/192 (21%), Positives = 74/192 (39%), Gaps = 23/192 (12%)
Query 1026 EAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSG 1085
E S++ IVN +N L V+ ++ +++ D KL G G + L G
Sbjct 26 ELNSSDTTAIVNTSNESLTDKNPVSESIFMLAGPDLKE---DLQKLKG-CRTGEAKLTKG 81
Query 1086 HNL-AKKCLHVVGPNLNAG---EDIQLLKAAYENF------NSQDILLAPLLSAGIFGAK 1135
NL A+ +H VGP + L + Y N S + ++++ G
Sbjct 82 FNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYP 141
Query 1136 PLQSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDS--KTE 1193
+ + ++TVR ++ ++ + + + V EA Q+ P K E
Sbjct 142 LEDATHIALRTVRR--FLEIHGETIEKVVFAVSDLE-----EATYQKLLPLYFPRSLKEE 194
Query 1194 EKSVVQKPVDVK 1205
+S+ P D+
Sbjct 195 NRSLPYLPADIG 206
>sp|P75033|Y153_MYCPN Uncharacterized ATP-dependent helicase MG140
homolog OS=Mycoplasma pneumoniae (strain ATCC 29342 / M129
/ Subtype 1) OX=272634 GN=MPN_153 PE=3 SV=1
Length=1113
Score = 61.6 bits (148), Expect = 3e-07, Method: Composition-based stats.
Identities = 53/278 (19%), Positives = 89/278 (32%), Gaps = 52/278 (19%)
Query 5652 TLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRT 5711
T E T N D VV DE S Y + R Y+ GD QL
Sbjct 681 TFESAALLTPNQ--RRLYDYVVIDEASQV--YLERAIPILYRGAKYIIAGDTKQLKPSNF 736
Query 5712 LLTKGTLEPE------------YFNSVCRLMKTIGPDMFLGTC-RRC-PAEIVDTVSALV 5757
+ + + + S+ +K + L R A ++ + +
Sbjct 737 FQARAEYDVDEEFEDGNVEAAVHSTSLLHFLKNRSRILTLLKFHYRSDSANLIAFTNNRI 796
Query 5758 YDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPA----WRKAVFI 5813
Y+N+L +A VI + N + V + L + + I
Sbjct 797 YNNELIFMNKATADKQVFIVHDVIDGIWRNNRNLQEARDVVQRLEQLTQTAEYQKSLGVI 856
Query 5814 SPYNSQNAVASKIL----------------------GLPTQTVDSSQGSEYDYVIFTQTT 5851
+Q + ++ GL + +++ QG E D +IF+
Sbjct 857 CFNKNQAELIEYMIDKQNNPLLNEWRDRVNAQGEYVGLFVKNIENVQGDERDIIIFSLGY 916
Query 5852 ETAHSC--------NVNRFNVAITRAKIGILCIMSDRD 5881
+ + + NR NVAITRAK I ++R
Sbjct 917 DRSVNSYGPISKQGGENRLNVAITRAKQRIELFKTNRA 954
>sp|Q9P0M6|H2AW_HUMAN Core histone macro-H2A.2 OS=Homo sapiens
OX=9606 GN=MACROH2A2 PE=1 SV=3
Length=372
Score = 60.5 bits (145), Expect = 3e-07, Method: Composition-based stats.
Identities = 27/124 (22%), Positives = 44/124 (35%), Gaps = 11/124 (9%)
Query 1035 IVNA--ANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKK 1091
IV+ A I LK G AL KA + + K GPL V + + L AK
Sbjct 215 IVHPTTAEIDLKEDIG--KALEKAGGKEFLETVKELRKSQGPLEVAEAAVSQSSGLAAKF 272
Query 1092 CLHVVGPNLNAGEDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCVQ 1145
+H P + + + L+ +N + P +G + QV ++
Sbjct 273 VIHCHIPQWGSDKCEEQLEETIKNCLSAAEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLK 332
Query 1146 TVRT 1149
+
Sbjct 333 AISA 336
>sp|Q8CCK0|H2AW_MOUSE Core histone macro-H2A.2 OS=Mus musculus
OX=10090 GN=Macroh2a2 PE=1 SV=3
Length=372
Score = 58.5 bits (140), Expect = 1e-06, Method: Composition-based stats.
Identities = 27/124 (22%), Positives = 44/124 (35%), Gaps = 11/124 (9%)
Query 1035 IVNA--ANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKK 1091
IV+ A I LK G AL KA + + K GPL V + + L AK
Sbjct 215 IVHPTTAEIDLKEEIG--KALEKAGGKEFLETVKELRKSQGPLEVAEAAVSQSSGLAAKF 272
Query 1092 CLHVVGPNLNAGEDIQLLKAAYENF------NSQDILLAPLLSAGIFGAKPLQSLQVCVQ 1145
+H P + + + L+ +N + P +G + QV ++
Sbjct 273 VIHCHIPQWGSDKCEEQLEETIKNCLSAAEDKKLKSVAFPPFPSGRNCFPKQTAAQVTLK 332
Query 1146 TVRT 1149
+
Sbjct 333 AISA 336
>sp|P18479|POLG_ZYMVC Genome polyprotein OS=Zucchini yellow mosaic
virus (strain California) OX=117128 PE=1 SV=2
Length=3080
Score = 58.5 bits (140), Expect = 3e-06, Method: Composition-based stats.
Identities = 59/295 (20%), Positives = 120/295 (41%), Gaps = 48/295 (16%)
Query 4823 DYYRYNLPTM---CDIRQLLFVVEVVDKY---FDCYDGGCINANQVIVNNLDKSAGFPFN 4876
D+++YN P D + L V+ V + F+ + I + I N+L+ A
Sbjct 2356 DFFKYNKPVTVNQLDHDKFLGAVDGVIRMMCDFEFNECRFITDPEEIYNSLNMKAAIGAQ 2415
Query 4877 KWGKARLYYDSMS-YEDQDALFAYTKR--NVIPTITQMNLKYAISAKNRAR--------- 4924
GK + Y++ + ++ + LF +R N + +LK + + R
Sbjct 2416 YRGKKKEYFEGLDDFDRERLLFQSCERLFNGYKGLWNGSLKAELRPLEKVRANKTRTFTA 2475
Query 4925 ----TVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
T+ G +C N +F++K LK +G +KFYGGW +++++
Sbjct 2476 APIDTLLGAKVCVDDFNNEFYRKNLK-------CPWTVGMTKFYGGWDKLMRSLPDGWLY 2528
Query 4981 PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVL-SEMVMC- 5038
H G + D ++ L + ++++ R + + + E + L +E+V
Sbjct 2529 CHADGSQF---DSSLTPAL--LNAVLIIR------SFYMEDWWVGQEMLENLYAEIVYTP 2577
Query 5039 ----GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYV 5089
G+++ K G +SG +T N++ + A + + +I +K V
Sbjct 2578 ILAPDGTIFKKFRGNNSGQPSTVVDNTLMVVISIYYACMK--FGWNCEEIENKLV 2630
>sp|Q9YLR1|POLN_HEVUS Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 3 (isolate Human/United States/US2) OX=509615
GN=ORF1 PE=3 SV=1
Length=1708
Score = 57.8 bits (138), Expect = 5e-06, Method: Composition-based stats.
Identities = 30/147 (20%), Positives = 58/147 (39%), Gaps = 17/147 (12%)
Query 1013 TDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLN 1072
D + + + + +VNA+N + GGG+ A + A S ++I
Sbjct 800 PDGAKVYAGSLXES----DCDWLVNASNPGHRPGGGLCHAFYQRFPEAF--YSTEFIMRE 853
Query 1073 GPLTVGGSCLLSGHNL-AKKCLHVVGPNLNAGEDIQLLKAAY-ENFNSQDILLAPLLSAG 1130
G L+ + L + +H V P+ ++ + L+AAY E + + PLL +G
Sbjct 854 G---------LAAYTLTPRPIIHAVAPDYRVEQNPKRLEAAYRETCSRRGTAAYPLLGSG 904
Query 1131 IFGAKPLQSLQVCVQTVRTQVYIAVND 1157
I+ S + R + + +
Sbjct 905 IYQVPVSLSFDAWERNHRPGDELYLTE 931
>sp|Q7JUR6|GDAP2_DROME Protein GDAP2 homolog OS=Drosophila melanogaster
OX=7227 GN=Gdap2 PE=2 SV=1
Length=540
Score = 55.4 bits (132), Expect = 2e-05, Method: Composition-based stats.
Identities = 31/188 (16%), Positives = 59/188 (31%), Gaps = 20/188 (11%)
Query 1028 QSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHN 1087
+ I N ++ L ++ + +++E +K G + G+N
Sbjct 77 TTLEVDAITNTSDETLTESNSISERIFAVAGNQLREELSTTVK---ECRTGDVRITRGYN 133
Query 1088 L-AKKCLHVVGPNLNAG---EDIQLLKAAYENFNSQ------DILLAPLLSAGIFGAKPL 1137
L AK LH V P L Y N + + +SA
Sbjct 134 LPAKYVLHTVAPAYREKFKTAAENTLHCCYRNVLCKAKELNLHTIALCNISAHQKSFPAD 193
Query 1138 QSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSV 1197
+ + ++T+R DK + V++ + + E D E ++
Sbjct 194 VAAHIALRTIRR-----YLDKCTLQVVILCVGSSERGTYEVL--APLYFPRDQLEERSAL 246
Query 1198 VQKPVDVK 1205
Q P D+
Sbjct 247 WQLPKDIG 254
>sp|Q6J8G2|POLN_HEVMG Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 3 (isolate Swine/United States/swUS1)
OX=512345 GN=ORF1 PE=3 SV=1
Length=1708
Score = 55.4 bits (132), Expect = 2e-05, Method: Composition-based stats.
Identities = 28/125 (22%), Positives = 52/125 (42%), Gaps = 13/125 (10%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL-AKKCL 1093
+VNA+N + GGG+ A + A ++I G L+ + L + +
Sbjct 818 LVNASNPGHRPGGGLCHAFYQRFPEAFYP--TEFIMREG---------LAAYTLTPRPII 866
Query 1094 HVVGPNLNAGEDIQLLKAAY-ENFNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVY 1152
H V P+ ++ + L+AAY E + + PLL +GI+ S + R
Sbjct 867 HAVAPDYRVEQNPKRLEAAYRETCSRRGTAAYPLLGSGIYQVPVSLSFDAWERNHRPGDE 926
Query 1153 IAVND 1157
+ + +
Sbjct 927 LYLTE 931
>sp|Q81862|POLN_HEVCH Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 1 (isolate Human/China/HeBei/1987) OX=652674
GN=ORF1 PE=1 SV=1
Length=1693
Score = 55.4 bits (132), Expect = 3e-05, Method: Composition-based stats.
Identities = 24/108 (22%), Positives = 41/108 (38%), Gaps = 11/108 (10%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLH 1094
+VNA+N+ + GGG+ A + + S G + + +H
Sbjct 803 LVNASNVDHRPGGGLCHAFYQRYPASFDAASFVMRD-------GAAAYT---LTPRPIIH 852
Query 1095 VVGPNLNAGEDIQLLKAAYENFNSQ-DILLAPLLSAGIFGAKPLQSLQ 1141
V P+ + ++L+AAY S+ PLL GI+ S
Sbjct 853 AVAPDYRLEHNPKMLEAAYRETCSRLGTAAYPLLGTGIYQVPIGPSFD 900
Score = 38.1 bits (87), Expect = 5.0, Method: Composition-based stats.
Identities = 55/305 (18%), Positives = 92/305 (30%), Gaps = 88/305 (29%)
Query 5574 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5633
G+ +Y G PG+GKS + A VD
Sbjct 966 GVVQYQFTAGVPGSGKSRSI-----------------TQADVD---------------VV 993
Query 5634 IIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLR 5693
++P R E + ++ F A T VV DE + L + R
Sbjct 994 VVPTR---ELRNAWRRRG---FAAFTPHTAARVTQGRRVVIDEAPSLPPHLLLLHMQRAA 1047
Query 5694 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5753
H +GDP Q+PA ++ E+ V + + P + RCPA++ + +
Sbjct 1048 TVH--LLGDPNQIPA---------IDFEHAGLVPAIRPDLAPTSWWHVTHRCPADVCELI 1096
Query 5754 SALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5813
+++ + + G +K VF
Sbjct 1097 RGAY------PMIQTTSRVLRSLFWGEPAV-----------------------GQKLVF- 1126
Query 5814 SPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR--FNVAITRAKI 5871
A+K + TV +QG+ Y T + +R VA+TR
Sbjct 1127 -------TQAAKAANPGSVTVHEAQGATYTETTIIATADARGLIQSSRAHAIVALTRHTE 1179
Query 5872 GILCI 5876
+ I
Sbjct 1180 KCVII 1184
>sp|Q03495|POLN_HEVME Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 2 (isolate Human/Mexico) OX=31768 GN=ORF1
PE=3 SV=1
Length=1691
Score = 55.1 bits (131), Expect = 3e-05, Method: Composition-based stats.
Identities = 28/130 (22%), Positives = 46/130 (35%), Gaps = 15/130 (12%)
Query 1013 TDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLN 1072
D I I + + +VNA+N + GGG+ A Q+ D +
Sbjct 783 PDGAKIYVGSIFESECTW----LVNASNAGHRPGGGLCHAF-------FQRYPDSFDATK 831
Query 1073 GPLTVGGSCLLSGHNLAKKCLHVVGPNLNAGEDIQLLKAAYENF-NSQDILLAPLLSAGI 1131
+ G + + +H V P+ + + L+AAY + PLL AGI
Sbjct 832 FVMRDGLAAYT---LTPRPIIHAVAPDYRLEHNPKRLEAAYRETCARRGTAAYPLLGAGI 888
Query 1132 FGAKPLQSLQ 1141
+ S
Sbjct 889 YQVPVSLSFD 898
Score = 37.3 bits (85), Expect = 7.2, Method: Composition-based stats.
Identities = 23/98 (23%), Positives = 39/98 (40%), Gaps = 11/98 (11%)
Query 5656 YVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTK 5715
F A T+ VV DE + L + R + H +GDP Q+PA
Sbjct 1008 AAFTPHTAARVTSGRRVVIDEAPSLPPHLLLLHMQRAASVH--LLGDPNQIPA------- 1058
Query 5716 GTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5753
++ E+ + + + P + RCPA++ + V
Sbjct 1059 --IDFEHTGLIPAIRPELVPTSWWHVTHRCPADVCELV 1094
>sp|P18478|POLG_WMV2U Genome polyprotein (Fragment) OS=Watermelon
mosaic virus II (isolate USA) OX=148360 PE=1 SV=3
Length=1017
Score = 54.3 bits (129), Expect = 5e-05, Method: Composition-based stats.
Identities = 57/279 (20%), Positives = 112/279 (40%), Gaps = 50/279 (18%)
Query 4823 DYYRYNLPTMCDI-------RQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPF 4875
D+++YN P + + + + V+ ++ F+ + + I +L+ A
Sbjct 291 DFFKYNKPVVLNEVDFNAFEKAVEGVITMMVD-FEFAECLFVTDPDEIYGSLNMKAAVGA 349
Query 4876 NKWGKARLYYDSM-SYEDQDALFAYTKR--NVIPTITQMNLKYAI-------SAKNRART 4925
GK + Y+ M S++ + L+ +R N I +LK + + K R T
Sbjct 350 QYKGKKQDYFSGMDSFDKERLLYLSCERLFNGEKGIWNGSLKAELRPIEKVQANKTRTFT 409
Query 4926 VA------GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVE 4979
A G +C N QF+ LK +G +KFYGGW +++++
Sbjct 410 AAPLDTLLGAKVCVDDFNNQFYSFNLK-------CPWTVGMTKFYGGWDKLMRSLPDGWT 462
Query 4980 TPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVL-SEMVM 5037
H G + D ++ P +L + S+ CC + + + E + L +E+V
Sbjct 463 YCHADGSQF---DSSLTPLLLNAVLSI-------RCCFMED--WWVGREMLENLYAEIVY 510
Query 5038 C-----GGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5071
G+++ K G +SG +T N++ + +
Sbjct 511 TPILAPDGTIFKKFRGNNSGQPSTVVDNTLMVVIAMYYS 549
>sp|P33424|POLN_HEVPA Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 1 (isolate Human/Pakistan/Sar-55) OX=33774
GN=ORF1 PE=1 SV=2
Length=1693
Score = 54.3 bits (129), Expect = 5e-05, Method: Composition-based stats.
Identities = 24/108 (22%), Positives = 40/108 (37%), Gaps = 11/108 (10%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLH 1094
+VNA+N+ + GGG+ A + + S G + + +H
Sbjct 803 LVNASNVDHRPGGGLCHAFYQRYPASFDAASFVMRD-------GAAAYT---LTPRPIIH 852
Query 1095 VVGPNLNAGEDIQLLKAAYENFNSQ-DILLAPLLSAGIFGAKPLQSLQ 1141
V P+ + + L+AAY S+ PLL GI+ S
Sbjct 853 AVAPDYRLEHNPKRLEAAYRETCSRLGTAAYPLLGTGIYQVPIGPSFD 900
Score = 38.1 bits (87), Expect = 4.9, Method: Composition-based stats.
Identities = 55/305 (18%), Positives = 92/305 (30%), Gaps = 88/305 (29%)
Query 5574 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5633
G+ +Y G PG+GKS + A VD
Sbjct 966 GVVQYQFTAGVPGSGKSRSI-----------------TQADVD---------------VV 993
Query 5634 IIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLR 5693
++P R E + ++ F A T VV DE + L + R
Sbjct 994 VVPTR---ELRNAWRRRG---FAAFTPHTAARVTQGRRVVIDEAPSLPPHLLLLHMQRAA 1047
Query 5694 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5753
H +GDP Q+PA ++ E+ V + + P + RCPA++ + +
Sbjct 1048 TVH--LLGDPNQIPA---------IDFEHAGLVPAIRPDLAPTSWWHVTHRCPADVCELI 1096
Query 5754 SALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5813
+++ + + G +K VF
Sbjct 1097 RGAY------PMIQTTSRVLRSLFWGEPAV-----------------------GQKLVF- 1126
Query 5814 SPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR--FNVAITRAKI 5871
A+K + TV +QG+ Y T + +R VA+TR
Sbjct 1127 -------TQAAKAANPGSVTVHEAQGATYTETTIIATADARGLIQSSRAHAIVALTRHTE 1179
Query 5872 GILCI 5876
+ I
Sbjct 1180 KCVII 1184
>sp|P29324|POLN_HEVBU Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 1 (isolate Human/Burma) OX=31767 GN=ORF1
PE=1 SV=1
Length=1693
Score = 54.3 bits (129), Expect = 5e-05, Method: Composition-based stats.
Identities = 24/108 (22%), Positives = 40/108 (37%), Gaps = 11/108 (10%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLH 1094
+VNA+N+ + GGG+ A + + S G + + +H
Sbjct 803 LVNASNVDHRPGGGLCHAFYQRYPASFDAASFVMRD-------GAAAYT---LTPRPIIH 852
Query 1095 VVGPNLNAGEDIQLLKAAYENFNSQ-DILLAPLLSAGIFGAKPLQSLQ 1141
V P+ + + L+AAY S+ PLL GI+ S
Sbjct 853 AVAPDYRLEHNPKRLEAAYRETCSRLGTAAYPLLGTGIYQVPIGPSFD 900
>sp|Q292F9|GDAP2_DROPS Protein GDAP2 homolog OS=Drosophila pseudoobscura
pseudoobscura OX=46245 GN=GA15091 PE=3 SV=1
Length=542
Score = 53.9 bits (128), Expect = 5e-05, Method: Composition-based stats.
Identities = 31/188 (16%), Positives = 59/188 (31%), Gaps = 20/188 (11%)
Query 1028 QSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHN 1087
+ + I N ++ L ++ + +++E +K G + G+N
Sbjct 79 TTLDVDAITNTSDETLTESNIISERILAVAGNQLREELSTNVK---ECRTGDVRITRGYN 135
Query 1088 L-AKKCLHVVGPNLNAG---EDIQLLKAAYENFNSQ------DILLAPLLSAGIFGAKPL 1137
L AK LH V P L Y N + + +S
Sbjct 136 LPAKYVLHTVAPTYREKFKTAAENTLHCCYRNVLCKAKELNLHTIALCNISVHQKSFPAD 195
Query 1138 QSLQVCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSV 1197
+ + ++T+R DK + V++ N + E D E ++
Sbjct 196 VAAHIALRTIRR-----YLDKCTLQVVILCVNSNERGTYEVL--APLYFPRDQLEERSAL 248
Query 1198 VQKPVDVK 1205
Q P D+
Sbjct 249 WQLPKDIG 256
>sp|Q9M041|BH140_ARATH Transcription factor bHLH140 OS=Arabidopsis
thaliana OX=3702 GN=BHLH140 PE=3 SV=1
Length=912
Score = 54.3 bits (129), Expect = 5e-05, Method: Composition-based stats.
Identities = 29/118 (25%), Positives = 44/118 (37%), Gaps = 14/118 (12%)
Query 1020 CVDIVK--EAQSANPMVIVNAANIHLK-HGGGVAGALNKATNGAMQKESDDYIKLNGPLT 1076
DI K + VI NA N LK GGGV A+ KA + E+ ++ N L
Sbjct 528 VGDITKLRSEGGLHCNVIANATNWRLKPGGGGVNAAIFKAAGPDL--ETATRVRAN-TLL 584
Query 1077 VGGSCLLSGHNLA--------KKCLHVVGPNLNAGEDIQLLKAAYENFNSQDILLAPL 1126
G + ++ + +HV+GPN+N L + + L
Sbjct 585 PGKAVVVPLPSTCPLHNAEGITHVIHVLGPNMNPNRPDNLNNDYTKGCKTLREAYTSL 642
>sp|Q89330|POLG_ZYMVR Genome polyprotein OS=Zucchini yellow mosaic
virus (strain Reunion Island) OX=117129 PE=3 SV=1
Length=3083
Score = 53.9 bits (128), Expect = 8e-05, Method: Composition-based stats.
Identities = 57/280 (20%), Positives = 113/280 (40%), Gaps = 46/280 (16%)
Query 4823 DYYRYNLPTMCDIRQLLFVVEVVDKY------FDCYDGGCINANQVIVNNLDKSAGFPFN 4876
D+++YN P + + +E VD F+ + I + I ++L+ A
Sbjct 2359 DFFKYNKPVIVNQLDHDKFLEAVDGVIRMMCDFEFNECRFITDPEEIYSSLNMKAAIGAQ 2418
Query 4877 KWGKARLYYDSM-SYEDQDALFAYTKR--NVIPTITQMNLKYAI-------SAKNRARTV 4926
GK + Y++ + +++ + LF +R N + +LK + + K R T
Sbjct 2419 YRGKKKEYFEGLDNFDMERLLFQSCERLFNGYKGLWNGSLKAELRPLEKVQANKTRTFTA 2478
Query 4927 A------GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
A G +C N +F+ K LK +G SKFYGGW +++ +
Sbjct 2479 APIDTLLGAKVCVDDFNNEFYSKNLK-------CPWTVGMSKFYGGWDKLMRALPDGWLY 2531
Query 4981 PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVL-SEMVMC- 5038
H G + D ++ L + ++++ R + + + E + L +E+V
Sbjct 2532 CHADGSQF---DSSLTPAL--LNAVLIIR------SFYMEDWWVGQEMLENLYAEIVYTP 2580
Query 5039 ----GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVN 5074
G+++ K G +SG +T N++ + A +
Sbjct 2581 ILAPDGTIFKKFRGNNSGQPSTVVDNTLMVVISIYYACIK 2620
>sp|O36979|POLG_ZYMVS Genome polyprotein OS=Zucchini yellow mosaic
virus (strain Singapore) OX=117130 PE=3 SV=2
Length=3083
Score = 53.5 bits (127), Expect = 1e-04, Method: Composition-based stats.
Identities = 57/277 (21%), Positives = 113/277 (41%), Gaps = 46/277 (17%)
Query 4823 DYYRYNLPTM---CDIRQLLFVVEVVDKY---FDCYDGGCINANQVIVNNLDKSAGFPFN 4876
D+++YN P + D + L V V + F+ + I + I ++L+ A
Sbjct 2359 DFFKYNKPVVVNQLDHDKFLGAVNGVIRMMCDFEFNECRFITDPEEIYDSLNMKAAIGAQ 2418
Query 4877 KWGKARLYYDSM-SYEDQDALFAYTKR--NVIPTITQMNLKYAI-------SAKNRARTV 4926
GK + Y++ + +++ + LF +R N + +LK + + K R T
Sbjct 2419 YRGKKKEYFEGLDNFDRERLLFQSCERLFNGHKGLWNGSLKAELRPLEKVQANKTRTFTA 2478
Query 4927 A------GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
A G +C N +F+ K LK +G +KFYGGW +++ +
Sbjct 2479 APIDTLLGAKVCVDDFNNEFYSKNLK-------CPWTVGMTKFYGGWDKLMRELPDGWLY 2531
Query 4981 PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVL-SEMVMC- 5038
H G + D ++ L + ++++ R + + + E + L +E+V
Sbjct 2532 CHADGSQF---DSSLTPAL--LNAVLIIR------SFYMEDWWVGQEMLENLYAEIVYTP 2580
Query 5039 ----GGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5071
G+++ K G +SG +T N++ + A
Sbjct 2581 ILAPDGTIFKKFRGNNSGQPSTVVDNTLMVVISIYYA 2617
>sp|Q9YRB3|RDRP_NCBVS Methyltransferase/helicase/RNA-directed
RNA polymerase OS=Nudaurelia capensis beta virus (isolate Pine
emperor moth/South Africa) OX=652108 PE=3 SV=1
Length=1925
Score = 53.1 bits (126), Expect = 1e-04, Method: Composition-based stats.
Identities = 34/171 (20%), Positives = 56/171 (33%), Gaps = 29/171 (17%)
Query 5583 GPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVE 5642
GPPG+GKS A ++Y A + DAL E S + P+R
Sbjct 566 GPPGSGKSRAAKPRFADLQGG-VLYCAPTRTLRDALDE-----------SVVHPSRV--- 610
Query 5643 CFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGD 5702
T + D++V DE + ++ + V +GD
Sbjct 611 --------CTYHNALHVAAKESGNRPFDVIVIDEAETTPACYVGTMHHASPSSRIVCLGD 662
Query 5703 PAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5753
P Q+ K L+P ++ T RCP ++++
Sbjct 663 PHQIGYIDFSDRKDDLKP------FSIIAAECRTRRFNTTYRCPQDVLNLP 707
>sp|P89659|RDRP_ORSVC Replicase large subunit OS=Odontoglossum
ringspot virus (isolate Korean Cy) OX=138661 PE=3 SV=2
Length=1612
Score = 52.8 bits (125), Expect = 1e-04, Method: Composition-based stats.
Identities = 65/410 (16%), Positives = 129/410 (31%), Gaps = 64/410 (16%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5636
K + + G PG GK+ + + + A + ++A +K +
Sbjct 820 KVTLVDGVPGCGKTKEILETVNFDED---LILVPGKEACKMIIKRA------NKSGHVRA 870
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
+ V D F ++ L T + + DE M ++ + A +
Sbjct 871 TKDNVRTVDSFLMH-------------LKPKTYNKLFIDEGLMLHTGCVNFLIALSHCRE 917
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5756
+ GD Q+P + P++F ++ + + L RCPA++ +++
Sbjct 918 AMVFGDTEQIPFINRVANFPY--PKHFATLVYDHREV---RRLSL--RCPADVTHFMNSK 970
Query 5757 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5816
YD K+ D +G + P+ ++ + KA
Sbjct 971 -YDGKVLCTNDVIRSVDAEVVRGK-------GVFNPKSKPLKGKIITFTQSDKAEL---- 1018
Query 5817 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCI 5876
+ G TV QG ++ V + T T I+++ +L
Sbjct 1019 KERGYEEVSTFG-EINTVHEIQGETFEDVSVVRLTPTPLEL--------ISKSSPHVLVA 1069
Query 5877 MSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFK 5936
++ ++ S+ + V+ D K+ G+ L V FK
Sbjct 1070 LTRHT--KSFKYYSVVLDPLVKVCSDLSKVSDFILDMYKVDAGI-----LXQLQVGSIFK 1122
Query 5937 TEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVR 5986
E L V IS M F + + G + + ++R
Sbjct 1123 GENLFV-------PCPKSGYISDMQFYYDTLLPGNSTILNEYDAVTMNLR 1165
>sp|A0A0D2UG83|H2AY_CAPO3 Histone macroH2A1.1 OS=Capsaspora owczarzaki
(strain ATCC 30864) OX=595528 GN=CAOG_004778 PE=1 SV=1
Length=368
Score = 51.2 bits (121), Expect = 2e-04, Method: Composition-based stats.
Identities = 42/192 (22%), Positives = 68/192 (35%), Gaps = 18/192 (9%)
Query 999 PEEPVNQFT----GYLKLTDNVAIKCVDIVKEAQSANPMVIVNAANIHLKHGGGVAGALN 1054
P++PV FT L L + + D+ + +V+ N + G V GA+
Sbjct 176 PKKPVRGFTILSKKTLHLGQTLYVVNGDLTE----VRCDAVVHPTNGTMSFAGQVGGAIR 231
Query 1055 KATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLA-KKCLHVVGPNL-NAGEDIQLLKAA 1112
A + E + Y+ + L V + + SGHNL K +HV PN NA L
Sbjct 232 AAAGAGVDAEVNSYMSEHSQLQVTKAAITSGHNLPSKWIVHVHSPNYSNAATATDALTQT 291
Query 1113 YEN------FNSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRTQVYIAVNDKALYEQVVM 1166
N S + P + +G + Q +Q + Y + ++V
Sbjct 292 IRNALTLADTKSIKTIAFPSIGSGNNHFPKHIAAQTILQAIS--AYFMSIMSSSIKEVYF 349
Query 1167 DYLDNLKPRVEA 1178
D V
Sbjct 350 VLFDQESINVYN 361
>sp|Q67724|RDRP_HASV Methyltransferase/helicase/RNA-directed RNA
polymerase OS=Helicoverpa armigera stunt virus OX=37206 PE=2
SV=1
Length=1704
Score = 52.0 bits (123), Expect = 3e-04, Method: Composition-based stats.
Identities = 52/285 (18%), Positives = 95/285 (33%), Gaps = 46/285 (16%)
Query 5574 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5633
G++ Y +GPPG+GK+ I AL + +Y A + +A+ + K +
Sbjct 603 GLEMY---EGPPGSGKTGTLIA-ALEAAGGKALYVAPTRELREAMDRRI-KPPSASRTQH 657
Query 5634 IIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLR 5693
+ A R T P VV DE M +++V+A
Sbjct 658 VALAILRR-----------------ATAEGAP---FATVVIDECFMFPLVYVAIVHALSP 697
Query 5694 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPD---MFLGTCRRCPAEIV 5750
+ V +GD Q+ G ++ + ++ L++ + +RCPA++V
Sbjct 698 SSRIVLVGDVHQI---------GFIDFQGTSANMPLVRDVVKQCRRRTFNQTKRCPADVV 748
Query 5751 DTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKA 5810
T L ++ C I+H N + ++ +
Sbjct 749 ATTFFQ----SLYPGCTTTSGCV-----ASISHVAPDYRNSQAQTLCFTQEEKSRHGAEG 799
Query 5811 VFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAH 5855
AS IL T + +E +++ T T H
Sbjct 800 AMTVHEAQGRTFASVILHYNGSTAEQKLLAEKSHLLVGITRHTNH 844
>sp|Q9WC28|POLN_HEVHY Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 1 (isolate Human/India/Hyderabad) OX=512346
GN=ORF1 PE=1 SV=1
Length=1693
Score = 51.6 bits (122), Expect = 4e-04, Method: Composition-based stats.
Identities = 23/108 (21%), Positives = 38/108 (35%), Gaps = 11/108 (10%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLH 1094
+VNA+N+ GGG+ A + + G + + +H
Sbjct 803 LVNASNVDHCPGGGLCHAFYQRYPASFDAACFVMRD-------GAAAYT---LTPRPIIH 852
Query 1095 VVGPNLNAGEDIQLLKAAYENFNSQ-DILLAPLLSAGIFGAKPLQSLQ 1141
V P+ + + L+AAY S+ PLL GI+ S
Sbjct 853 RVAPDYRLEHNPKRLEAAYRETCSRLGTAAYPLLGTGIYQVPIGPSFD 900
>sp|Q01901|POLG_PRSVH Genome polyprotein OS=Papaya ringspot virus
(strain P / mutant HA) OX=31731 PE=3 SV=2
Length=3344
Score = 51.6 bits (122), Expect = 4e-04, Method: Composition-based stats.
Identities = 61/317 (19%), Positives = 113/317 (36%), Gaps = 47/317 (15%)
Query 4850 DCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYT-------KR 4902
+C + I ++VI+ L+ A GK R Y++ + E + AL + +
Sbjct 2624 ECPELEYITDSEVIIQALNMDAAVGALYTGKKRKYFEGSTVEHRQALVRKSCERLYEGRM 2683
Query 4903 NVIPTITQMNLKYA---ISAKNRARTVA------GVSICSTMTNRQFHQKLLKSIAATRG 4953
V + L+ A ++ K R+ T A G +C N F+ K ++
Sbjct 2684 GVWNGSLKAELRPAEKVLAKKTRSFTAAPLDTLLGAKVCVDDFNNWFYSKNME------- 2736
Query 4954 ATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHN 5012
+G +KFY GW LK G + D ++ P +L + S+ L +
Sbjct 2737 CPWTVGMTKFYKGWDEFLKKFPDGWVYCDADGSQF---DSSLTPYLLNAVLSIRLWAMED 2793
Query 5013 TCCNLSHRFYRLANECAQVLSEMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5071
L N ++ ++ G++ K G +SG +T N++ + A
Sbjct 2794 ----WDIGEQMLKNLYGEITYTPILTPDGTIVKKFKGNNSGQPSTVVDNTLMVLITMYYA 2849
Query 5072 NVNALLSTDGNK------IADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKH---- 5121
A T + I + H +E + + + Y + ++H
Sbjct 2850 LRKAGYDTKTQEDMCVFYINGDDLCIAIHPDHEHVLDSFSSSFAELGLKYDFAQRHRNKQ 2909
Query 5122 --FSMM---ILSDDAVV 5133
+ M IL DD +
Sbjct 2910 NLWFMSHRGILIDDIYI 2926
>sp|Q9J942|RDRP_TRVPP Replicase large subunit OS=Tobacco rattle
virus (isolate PpK20) OX=652939 PE=3 SV=2
Length=1707
Score = 51.2 bits (121), Expect = 4e-04, Method: Composition-based stats.
Identities = 61/303 (20%), Positives = 107/303 (35%), Gaps = 54/303 (18%)
Query 5578 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEK-ALKYLPIDKCSRIIP 5636
+ + G PG GKS + P +V + AA D L E+ A K P
Sbjct 899 FELVDGVPGCGKSTMIVN--SANPCVDVVL-STGRAATDDLIERFASKGFP-------CK 948
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
+ RV+ D F + C +L T D++ FDE MA + AK
Sbjct 949 LKRRVKTVDSF--------LMHCVDGSL---TGDVLHFDEALMAHAGMVYFCAQIAGAKR 997
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5756
+ GD Q+ + + F+S+ + R PA++ ++
Sbjct 998 CICQGDQNQISFK----PRVSQVDLRFSSLVGKFDIVTEKR---ETYRSPADVAAVLNK- 1049
Query 5757 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV-REFLTRNPAWRKAVFISP 5815
+Y G + ++A + +V +E ++ P + F+
Sbjct 1050 -------------------YYTGDVRTHNATANSMTVRKIVSKEQVSLKPGAQYITFLQS 1090
Query 5816 YNSQ--NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR--FNVAITRAKI 5871
+ N +A + + TV SQG + V+ +T T S R VA++R
Sbjct 1091 EKKELVNLLALRKVAAKVSTVHESQGETFKDVVLVRTKPTDDSIARGREYLIVALSRHTQ 1150
Query 5872 GIL 5874
++
Sbjct 1151 SLV 1153
>sp|P05080|194K_TRVSY Replicase large subunit OS=Tobacco rattle
virus (strain SYM) OX=12298 PE=3 SV=2
Length=1707
Score = 51.2 bits (121), Expect = 4e-04, Method: Composition-based stats.
Identities = 61/303 (20%), Positives = 107/303 (35%), Gaps = 54/303 (18%)
Query 5578 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEK-ALKYLPIDKCSRIIP 5636
+ + G PG GKS + P +V + AA D L E+ A K P
Sbjct 899 FELVDGVPGCGKSTMIVN--SANPCVDVVL-STGRAATDDLIERFASKGFP-------CK 948
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
+ RV+ D F + C +L T D++ FDE MA + AK
Sbjct 949 LKRRVKTVDSF--------LMHCVDGSL---TGDVLHFDEALMAHAGMVYFCAQIAGAKR 997
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5756
+ GD Q+ + + F+S+ + R PA++ ++
Sbjct 998 CICQGDQNQISFK----PRVSQVDLRFSSLVGKFDIVTEKR---ETYRSPADVAAVLNK- 1049
Query 5757 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVV-REFLTRNPAWRKAVFISP 5815
+Y G + ++A + +V +E ++ P + F+
Sbjct 1050 -------------------YYTGDVRTHNATANSMTVRKIVSKEQVSLKPGAQYITFLQS 1090
Query 5816 YNSQ--NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR--FNVAITRAKI 5871
+ N +A + + TV SQG + V+ +T T S R VA++R
Sbjct 1091 EKKELVNLLALRKVAAKVSTVHESQGETFKDVVLVRTKPTDDSIARGREYLIVALSRHTQ 1150
Query 5872 GIL 5874
++
Sbjct 1151 SLV 1153
>sp|Q04610|POLN_HEVMY Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 1 (isolate Human/Myanmar/HEVNE8L) OX=31769
GN=ORF1 PE=1 SV=1
Length=1693
Score = 51.2 bits (121), Expect = 5e-04, Method: Composition-based stats.
Identities = 23/108 (21%), Positives = 39/108 (36%), Gaps = 11/108 (10%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLH 1094
+VNA+N+ + GGG+ A + + S G + + +H
Sbjct 803 LVNASNVDHRPGGGLCHAFYQRYPASFDAASFVMRD-------GAAAYT---LTPRPIIH 852
Query 1095 VVGPNLNAGEDIQLLKAAYENFNSQ-DILLAPLLSAGIFGAKPLQSLQ 1141
V P+ + + L+AAY S+ LL GI+ S
Sbjct 853 AVAPDYRLEHNPKRLEAAYRETCSRLGTAAYSLLGTGIYQVPIGPSFD 900
Score = 41.2 bits (95), Expect = 0.53, Method: Composition-based stats.
Identities = 51/305 (17%), Positives = 88/305 (29%), Gaps = 88/305 (29%)
Query 5574 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5633
G+ +Y G PG+GKS + V + +A + +R
Sbjct 966 GVVQYQFTAGVPGSGKSRSITQADVD------VVVVPTRELRNAWRRRGFAAFNPHTAAR 1019
Query 5634 IIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLR 5693
+ R VV DE + L + R
Sbjct 1020 VTQGRR--------------------------------VVIDEAPSLPPHLLLLHMQRAA 1047
Query 5694 AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTV 5753
H +GDP Q+PA ++ E+ V + +GP + RCPA++ + +
Sbjct 1048 TVH--LLGDPNQIPA---------IDFEHAGLVPAIRPDLGPTSWWHVTHRCPADVCELI 1096
Query 5754 SALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5813
+++ + + G +K VF
Sbjct 1097 RGAY------PMIQTTSRVLRSLFWGEPAV-----------------------GQKLVF- 1126
Query 5814 SPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR--FNVAITRAKI 5871
A+K + TV +QG+ Y T + +R VA+TR
Sbjct 1127 -------TQAAKAANPGSVTVHEAQGATYTETTIIATADARGLIQSSRAHAIVALTRHTE 1179
Query 5872 GILCI 5876
+ I
Sbjct 1180 KFVII 1184
>sp|Q9QBU0|RDRP_PMTVS Replicase large subunit OS=Potato mop-top
virus (isolate Potato/Sweden/Sw) OX=652839 GN=rep PE=3 SV=3
Length=1812
Score = 51.2 bits (121), Expect = 5e-04, Method: Composition-based stats.
Identities = 59/310 (19%), Positives = 106/310 (34%), Gaps = 60/310 (19%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5636
+ + + G PG GKS + + A + V T AA D + K +++
Sbjct 1008 RITLVDGVPGCGKSTYVVKEANL--VNQYVVTIGREAAED--LRERFKSERNATATQLK- 1062
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
RV D + +N T ++ A+++ FDE MA + L A+
Sbjct 1063 ---RVRTVDSYLLNDT-------------QSRANVLHFDEALMAHAGMVYFCADDLSARS 1106
Query 5697 YVYIGDPAQLP--APRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVS 5754
+ GD Q+P +T + E N V + + R P ++ ++
Sbjct 1107 VICQGDSQQIPFINRVESITLRYSKLEIDNVVEKRLT-----------YRSPLDVASYLT 1155
Query 5755 AL-VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFI 5813
Y + + + K ++S + P+I P + F+
Sbjct 1156 KKNFYGTSVVTSANPLVRSLKTV---GPRDGMTSIYSIPKI----------PGTQYLTFL 1202
Query 5814 SPYNSQNAVASKILG---LPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN------V 5864
S+ + LG TV SQG YD V+ + T + N V
Sbjct 1203 ---QSEKEEMRQYLGRGNWNVNTVHESQGKTYDNVVLCRLKATDNEIYPGGRNSSPYMVV 1259
Query 5865 AITRAKIGIL 5874
+TR + ++
Sbjct 1260 GVTRHRRSLV 1269
>sp|P69514|RDRP_CGMVS Replicase large subunit OS=Cucumber green
mottle mosaic virus (strain watermelon SH) OX=12236 PE=3 SV=1
Length=1648
Score = 51.2 bits (121), Expect = 5e-04, Method: Composition-based stats.
Identities = 49/306 (16%), Positives = 94/306 (31%), Gaps = 62/306 (20%)
Query 5578 YSTLQGPPGTGKSHFAIGLALYYPSARI-----VYTACSHAAVDALCEKALKYLPIDKCS 5632
+ + G PG GK+ I AR+ + A + +A +
Sbjct 858 ITLVDGVPGCGKTAEII--------ARVNWKTDLVLTPGREAAAMIRRRACALHKSPVAT 909
Query 5633 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5692
V FD F +N + + D V DE M L+
Sbjct 910 -----NDNVRTFDSFVMNRKIFK-------------FDAVYVDEGLMVHTGLLNFALKIS 951
Query 5693 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5752
K GD Q+P ++ +Y + L+ ++ RCP ++
Sbjct 952 GCKKAFVFGDAKQIPFINRVMN-----FDYPKELRTLIVDNVERRYVT--HRCPRDVTSF 1004
Query 5753 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNP-AWRKAV 5811
++ + +K A + + + I RP++ ++ + + ++++
Sbjct 1005 LNTI--------YKAAVATTSPVVHSVKAIKVSGAGILRPELTKIKGKIITFTQSDKQSL 1056
Query 5812 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVN---RFNVAITR 5868
S YN TV QG ++ + T T VA+TR
Sbjct 1057 IKSGYN------------DVNTVHEIQGETFEETAVVRATPTPIGLIARDSPHVLVALTR 1104
Query 5869 AKIGIL 5874
++
Sbjct 1105 HTKAMV 1110
>sp|Q9IVZ9|POLN_HEVCT Non-structural polyprotein pORF1 OS=Hepatitis
E virus genotype 4 (isolate Human/China/T1) OX=509627
GN=ORF1 PE=3 SV=1
Length=1707
Score = 50.8 bits (120), Expect = 6e-04, Method: Composition-based stats.
Identities = 30/185 (16%), Positives = 59/185 (32%), Gaps = 31/185 (17%)
Query 1035 IVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNL----AK 1090
+VNA+N + GGG+ A ES D + G +
Sbjct 817 LVNASNPGHRPGGGLCHAFY-----QRFPESFD---------PAEFIMSDGFAAYTLTPR 862
Query 1091 KCLHVVGPNLNAGEDIQLLKAAYENF-NSQDILLAPLLSAGIFGAKPLQSLQVCVQTVRT 1149
+H V P+ + + L+AAY + + PLL GI+ S + R
Sbjct 863 PIIHAVAPDYRVEHNPKRLEAAYRETCSRRGTAAYPLLGVGIYRVPVGLSFDAWERNHRP 922
Query 1150 QVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQKPVDVKPKIK 1209
+ + + A + + + +P + + ++ + +
Sbjct 923 GDELYLTEPA------IAWFEANRPTL------PALTITEDTARTANLALELDAATEVGR 970
Query 1210 ACIDE 1214
AC+
Sbjct 971 ACVGC 975
Score = 37.7 bits (86), Expect = 5.3, Method: Composition-based stats.
Identities = 33/186 (18%), Positives = 56/186 (30%), Gaps = 48/186 (26%)
Query 5693 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5752
RA +GDP Q+PA ++ E+ V + + P + RCPA++ +
Sbjct 1059 RASSVHLLGDPNQIPA---------IDFEHAGLVPAIRPELVPTKWWHLTYRCPADVCEL 1109
Query 5753 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVF 5812
+S + R F P + VF
Sbjct 1110 -----------------------IRGAYPKIQTASRVLR------SLFWEEPPVGQNLVF 1140
Query 5813 ISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR--FNVAITRAK 5870
+ N A TV +QG+ + T + +R VA+TR
Sbjct 1141 TQAAKAANPGAI--------TVHEAQGATFTETTIIATADARGLIQSSRAHAIVALTRHT 1192
Query 5871 IGILCI 5876
+ +
Sbjct 1193 EKCVVV 1198
>sp|Q84133|RDRP_ORSVS Replicase large subunit OS=Odontoglossum
ringspot virus (isolate Singapore 1) OX=138662 PE=3 SV=2
Length=1612
Score = 50.8 bits (120), Expect = 7e-04, Method: Composition-based stats.
Identities = 68/412 (17%), Positives = 128/412 (31%), Gaps = 64/412 (16%)
Query 5575 MQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRI 5634
M K + + G PG GK+ + + + A + ++A +K +
Sbjct 818 MPKVTLVDGVPGCGKTKEILETVNFDED---LILVPGKEACKMIIKRA------NKSGHV 868
Query 5635 IPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRA 5694
R V D F ++ L T + + DE M ++ + A
Sbjct 869 RATRDNVRTVDSFLMH-------------LKPKTYNKLFIDEGLMLHTGCVNFLVALSHC 915
Query 5695 KHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVS 5754
+ + GD Q+P + P++F C + + L RCPA++ ++
Sbjct 916 REAMVFGDAEQIPFINRVANFPY--PKHFRYTCLYHREV---RRLSL--RCPADVTHFMN 968
Query 5755 ALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFIS 5814
+ YD K+ D +G + P+ ++ + KA
Sbjct 969 SK-YDGKVLCTNDVIRSVDAEVVRGK-------GVFNPKSKPLKGKIITFTQSDKAEL-- 1018
Query 5815 PYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGIL 5874
+ G TV QG ++ V + T T I+++ +L
Sbjct 1019 --KERGYEEVSTFG-EINTVHEIQGETFEDVSVVRLTPTPLEL--------ISKSSPHVL 1067
Query 5875 CIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIK 5934
++ ++ S+ + V+ D K+ G+ L V
Sbjct 1068 VALTRHT--KSFKYYSVVLDPLVKVWSDLSKVSDFILDMYKVDAGI-----LXQLQVGSI 1120
Query 5935 FKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVR 5986
FK E L V IS M + V G + + ++R
Sbjct 1121 FKGENLFV-------PCPKSGYISDMQTYYDTLVPGNSTILNEYDAVTMNLR 1165
>sp|P17595|ALPHA_BSMV Replication protein alpha-A OS=Barley stripe
mosaic virus OX=12327 PE=1 SV=1
Length=1139
Score = 50.4 bits (119), Expect = 9e-04, Method: Composition-based stats.
Identities = 56/298 (19%), Positives = 100/298 (34%), Gaps = 40/298 (13%)
Query 5563 FSSNVANYQKVGMQ--KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCE 5620
++ V Y V + ++ + G PG GKS + R V A D L E
Sbjct 816 YNKLVDVYALVADRPLRFELIDGVPGCGKSTMILN---SCDIRREVVVGEGRNATDDLRE 872
Query 5621 KALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMA 5680
+ + ++ + A RV D AD FDE
Sbjct 873 RFKRKKNLNSKT----ANHRVRTLD-----------SLLLAEGPCVPQADRFHFDEALKV 917
Query 5681 TNYDLSVVNARLRAKHYVYIGDPAQLP--APRTLLTKGTLEPEYFNSVCRLMKTIGPDMF 5738
+ +L A + GD AQLP + P+Y ++ I P +
Sbjct 918 HYGAIMFCADKLGASEILAQGDRAQLPMICRVEGIELQFQSPDYTKTI------INPKL- 970
Query 5739 LGTCRRCPAEIVDTVSAL-VYDNKLKAHKDKSAQCFK--MFYKGVITHDVSSAINRPQIG 5795
R P ++ +SA Y K K ++ K ++ +G T + ++ +
Sbjct 971 --RSYRIPGDVAFYLSAKEFYKVKGIPQKVITSNSVKRSLYARGETTPERFVSLLDVPVR 1028
Query 5796 VVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTET 5853
+LT A ++++ + + + T+ +QG Y+ VI + T
Sbjct 1029 KDTHYLTFLQAEKESLM------SHLIPKGVKKESISTIHEAQGGTYENVILVRLQRT 1080
>sp|P20127|POLR_OYMV RNA replicase polyprotein OS=Ononis yellow
mosaic virus OX=12153 PE=3 SV=1
Length=1776
Score = 49.7 bits (117), Expect = 0.001, Method: Composition-based stats.
Identities = 58/302 (19%), Positives = 92/302 (30%), Gaps = 73/302 (24%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG GKSH L L A ++ + +
Sbjct 897 IAGFPGCGKSHPIQKL---------------------LQTPAFRHFRLSVPT-------- 927
Query 5641 VECFDKFKVN---STLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR-LRAKH 5696
E ++K + E + CT +++I+V DEI L ++ +
Sbjct 928 NELRSEWKRDLNLPESEVWRLCTWETALFKSSNILVVDEIYKLPRGYLDLILLADPSIQL 987
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5756
+ +GDP Q + + RL K I D + RCP + D
Sbjct 988 VIMLGDPLQ--GEYHSSHPSSSNSRLESETTRLSKYI--DCYCWWTYRCPKAVADLFGVK 1043
Query 5757 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5816
+++ +G I +S N P +V T N
Sbjct 1044 TFNSN----------------EGFIRAVLSHPPNLP--NLVNSIATANTMQS-------- 1077
Query 5817 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCI 5876
LG T+ SSQG Y + + VA+TR++ GI I
Sbjct 1078 ----------LGHHALTISSSQGMTYSDPVTVLLDRHSLLITPQTALVALTRSRSGIYFI 1127
Query 5877 MS 5878
S
Sbjct 1128 GS 1129
>sp|Q5UQ92|YR530_MIMIV Uncharacterized protein R530 OS=Acanthamoeba
polyphaga mimivirus OX=212035 GN=MIMI_R530 PE=4 SV=1
Length=494
Score = 48.9 bits (115), Expect = 0.002, Method: Composition-based stats.
Identities = 35/179 (20%), Positives = 70/179 (39%), Gaps = 20/179 (11%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIV----YTACSHAAVDALCEKALKYLPIDKCS 5632
K L G G+GK++ + + ++ Y A +H A+ L ++ I+
Sbjct 23 KIFYLIGFAGSGKTYTISKITKKFLVDELIENIYYCAPTHKALKVL--ESYIKSNINASD 80
Query 5633 RIIPARARV---ECFDKFKV---NSTLEQYVFCTVNA--LPETTADIVVFDEISMATNYD 5684
+ + + + +FK T + T + L + ++VV DE SM +
Sbjct 81 KDLSNKIKFMTIHKLLEFKPIIQTETGSKVFKSTKESKFLKNISKNLVVIDECSMISQEM 140
Query 5685 LSVVNARLR--AKHYVYIGDPAQLPA----PRTLLTKGTLEPEYFNSVCRLMKTIGPDM 5737
+ +N + +Y+GDP QLP + + +Y + +M+T D+
Sbjct 141 VDELNKYINLYPIKIIYMGDPKQLPPVGEVESLIFSTIPNNYQYHIVLDEIMRTNSVDI 199
>sp|Q01681|POLG_PPVEA Genome polyprotein (Fragment) OS=Plum pox
potyvirus (strain El amar) OX=31738 PE=2 SV=1
Length=1518
Score = 48.9 bits (115), Expect = 0.002, Method: Composition-based stats.
Identities = 56/348 (16%), Positives = 118/348 (34%), Gaps = 37/348 (11%)
Query 4814 DGNAAISDYDYYRYNLP-TMCDIRQLLFVVEVV------DKYFDCYDGGCINANQVIVNN 4866
+ +A + D Y ++ D Q V+VV + +C + + I +
Sbjct 733 NKDAYVKDLMKYSKSIVVGAVDCEQFERAVDVVISMLISKGFSEC---SYVTDPEEIFSA 789
Query 4867 LDKSAGFPFNKWGKARLYYDSMSYEDQDALF-AYTKRNVI--PTITQMNLKYAISAKNRA 4923
L+ A GK R Y+ S +++ A KR + + +LK + K +
Sbjct 790 LNMKAAVGALYSGKKRDYFKDTSELEKEEFVRASCKRLFMGKKGVWNGSLKAELRPKEKV 849
Query 4924 RTVAGVSICSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKTVYSD 4977
S + + K+ + +G +KF GGW +L+ +
Sbjct 850 EANKTRSFTAAPIDTLLGGKVCVDDFNNQFYSLNLHCPWSVGMTKFRGGWDKLLRALPDG 909
Query 4978 VETPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMV 5036
G + D ++ P ++ + ++ LA L+N +++ +
Sbjct 910 WIYCDADGSQF---DSSLSPYLINAVLNIRLA----FMEEWDIGEQMLSNLYTEIVYTPI 962
Query 5037 MC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKI------ADKYV 5089
G++ K G +SG +T N++ I + + D ++ +
Sbjct 963 ATPDGTIVKKFKGNNSGQPSTVVDNTLMVILAMTYSLLKLGYHPDTHECICRYFVNGDDL 1022
Query 5090 RNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFS---MMILSDDAVVC 5134
H YE +Y + Y + K + + +S ++C
Sbjct 1023 VLAVHPAYESIYDELQHHFSQLGLNYTFTTKTENKEDLWFMSHKGIMC 1070
>sp|P08411|POLN_SFV Polyprotein P1234 OS=Semliki forest virus
OX=11033 PE=1 SV=2
Length=2432
Score = 48.5 bits (114), Expect = 0.003, Method: Composition-based stats.
Identities = 39/178 (22%), Positives = 60/178 (34%), Gaps = 28/178 (16%)
Query 1037 NAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGHNLAKKCLHVV 1096
NAAN G GV A+ K A VG + + +H V
Sbjct 1357 NAANARGTVGDGVCRAVAKKWPSAF---------KGAATPVGTIKTVMCGSYP--VIHAV 1405
Query 1097 GPNLNAGEDIQ---LLKAAYENF------NSQDILLAPLLSAGIFGA------KPLQSLQ 1141
PN +A + + L A Y S + PLLS G+F + L L
Sbjct 1406 APNFSATTEAEGDRELAAVYRAVAAEVNRLSLSSVAIPLLSTGVFSGGRDRLQQSLNHLF 1465
Query 1142 VCVQTVRTQVYIAVNDKALYEQVVMDYLDNLKPRVEAPKQEEPPNTEDSKTEEKSVVQ 1199
+ V I DK+ +E+ + + +D VE + T+ + S +
Sbjct 1466 TAMDATDADVTIYCRDKS-WEKKIQEAIDMRTA-VELLNDDVELTTDLVRVHPDSSLV 1521
Score = 43.5 bits (101), Expect = 0.11, Method: Composition-based stats.
Identities = 46/259 (18%), Positives = 76/259 (29%), Gaps = 65/259 (25%)
Query 5581 LQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARAR 5640
+ G PG+GKS L H V + + C I+
Sbjct 721 VFGVPGSGKSAIIKSLVT------------KHDLVTS--------GKKENCQEIVND--- 757
Query 5641 VECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK-HYVY 5699
V+ + + + DI+ DE + L + A ++ + V
Sbjct 758 VKKHRGLDIQAKTVDSILLNG---CRRAVDILYVDEAFACHSGTLLALIALVKPRSKVVL 814
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
GDP Q + K VC RRC + VS L Y
Sbjct 815 CGDPKQCGFFNMMQLKVNFNHNICTEVCHK----------SISRRCTRPVTAIVSTLHYG 864
Query 5760 NKLKAHKDKSA-------------------QCFKMFYKGVI----THDVSSA-----INR 5791
K++ + CF+ + K + H+V +A + R
Sbjct 865 GKMRTTNPCNKPIIIDTTGQTKPKPGDIVLTCFRGWVKQLQLDYRGHEVMTAAASQGLTR 924
Query 5792 PQIGVVREFLTRNPAWRKA 5810
+ VR+ + NP + A
Sbjct 925 KGVYAVRQKVNENPLYAPA 943
>sp|O56075|POLG_PEMVM Genome polyprotein OS=Peanut mottle virus
(strain M) OX=103926 PE=3 SV=1
Length=3099
Score = 48.1 bits (113), Expect = 0.005, Method: Composition-based stats.
Identities = 35/223 (16%), Positives = 81/223 (36%), Gaps = 30/223 (13%)
Query 4857 INANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQM----- 4911
+ + I+++L+ A GK + Y++S+S ++ + + + +M
Sbjct 2415 VTDEEAILDSLNMKAAVGALYKGKKKEYFESLSEPEKHHIVQASCERL--FYGEMGVWNG 2472
Query 4912 NLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYG 4965
+LK + K + + + + K R +G +KFYG
Sbjct 2473 SLKAELRPKEKVALNKTRTFTAAPIDTLLGGKCCVDDFNNRFYSLNIEGPWTVGMTKFYG 2532
Query 4966 GWHNMLKTVYSDVETPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRL 5024
GW +++ + H G + D ++ P +L + ++ L ++
Sbjct 2533 GWDKLMRKLPDGWRYCHADGSQF---DSSLTPFLLNAVLAVRL--------MFMEDWWVG 2581
Query 5025 ANECAQVLSEMVMC-----GGSLYVKPGGTSSGDATTAYANSV 5062
+E++ G++ K G +SG +T N++
Sbjct 2582 EQMLRNFYTEIIYTPILTPDGTIVKKFKGNNSGQPSTVVDNTL 2624
>sp|P09814|POLG_TVMV Genome polyprotein OS=Tobacco vein mottling
virus OX=12228 PE=1 SV=2
Length=3023
Score = 48.1 bits (113), Expect = 0.005, Method: Composition-based stats.
Identities = 54/301 (18%), Positives = 101/301 (34%), Gaps = 48/301 (16%)
Query 4814 DGNAAISDYDYYRYNLP-TMCDIRQLLFVVEVVDKYFDCY---DGGCINANQVIVNNLDK 4869
+ A I D Y + D ++V+ + + + + Q I N L+
Sbjct 2307 NKEAYIKDIMKYSKQIVVGSVDCDTFESSLKVLSRKMKEWGFENLEYVTDEQTIKNALNM 2366
Query 4870 SAGFPFNKWGKARLYYDSMSYEDQDALFAYT----------------KRNVIPTITQMNL 4913
A GK + Y++ +S + L + K + P +
Sbjct 2367 DAAVGALYSGKKKQYFEDLSDDAVANLVQKSCLRLFKNKLGVWNGSLKAELRPFEKLIEN 2426
Query 4914 KYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKT 4973
K T+ G +C N F+ K + +G +KFYGGW+ +L
Sbjct 2427 KTRTFTAAPIETLLGGKVCVDDFNNHFYSKHI-------QCPWSVGMTKFYGGWNELLGK 2479
Query 4974 VYSDVETPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVL 5032
+ G + D ++ P ++ + L L+ + + + Q L
Sbjct 2480 LPDGWVYCDADGSQF---DSSLSPYLINAVLRLRLSSMEE---------WDVGQKMLQNL 2527
Query 5033 -SEMVMC-----GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIAD 5086
+E+V G++ K G +SG +T N++ + A + L D N D
Sbjct 2528 YTEIVYTPISTPDGTIVKKFKGNNSGQPSTVVDNTLMVVLAMYYA--LSKLGVDINSQED 2585
Query 5087 K 5087
Sbjct 2586 V 2586
>sp|Q58914|Y1519_METJA Uncharacterized protein MJ1519 OS=Methanocaldococcus
jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1
/ JCM 10045 / NBRC 100440) OX=243232 GN=MJ1519 PE=4 SV=1
Length=1175
Score = 47.4 bits (111), Expect = 0.006, Method: Composition-based stats.
Identities = 34/226 (15%), Positives = 70/226 (31%), Gaps = 22/226 (10%)
Query 5575 MQKYSTLQGPPGTGKSHFAIGLALYYPS----ARIVYTACSHAAVDALCEKALKYLPIDK 5630
+ L GP GTGK+ + +I + + + EK
Sbjct 578 KNRVGILTGPAGTGKTTVIKTIMELMKEVLGLNKIYILTPTGKSAMVVNEKLNNLATAKT 637
Query 5631 CSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNA 5690
R I F + + + D ++ DE SM + +
Sbjct 638 IHRYIAEE-----FKDYFEGDNYFILRLDKITGNDKKEIDALIIDESSMVDIETMGRLLG 692
Query 5691 RLR---AKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5747
++ K+ +++GD QLP + G + +N + ++ L R +
Sbjct 693 TIKLDNLKYLIFVGDINQLPP----VGAGKPFYDIYNYLEKVNPQSICK--LEIVLRADS 746
Query 5748 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQ 5793
+ + +S L D K++ + +K T + +
Sbjct 747 KKIVELSKLFLDID----KEERIKILNEMFKNKETLGDNEIYRIKE 788
>sp|Q05983|RDRP_RBDVR Methyltransferase/helicase/RNA-directed
RNA polymerase OS=Raspberry bushy dwarf virus (isolate Malling
Jewel raspberry/R15) OX=652675 PE=3 SV=1
Length=1694
Score = 47.0 bits (110), Expect = 0.008, Method: Composition-based stats.
Identities = 57/355 (16%), Positives = 109/355 (31%), Gaps = 60/355 (17%)
Query 5580 TLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARA 5639
+ G G GK+ + Y P I+ + A VD + K
Sbjct 856 LVDGVTGCGKTTEIVR--RYRPG--ILILSVCKANVDEIRRKLAAV-------------- 897
Query 5640 RVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVY 5699
K T++ Y+ + D + DE ++ L + +
Sbjct 898 ------DSKFIRTVDSYLLSPSVT---GSCDELFIDEYGLSHPGILLLAIHISGIRKVTL 948
Query 5700 IGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYD 5759
GD Q+P L P +NSV + ++ T RCP +I ++ +
Sbjct 949 FGDSEQIPFCNRLADF----PLKYNSVEDVGLNFDREIR-STTYRCPQDITLSLQKMYKT 1003
Query 5760 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5819
+K + K + +A + P + + + +
Sbjct 1004 KPIKTVSTVESSITIKPIKSEFEIPLPNAFDGPVLY-----ICMTKHDESLLKL------ 1052
Query 5820 NAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR----FNVAITRAKIGILC 5875
A + + +TV ++QG Y V++ + T T + R VAI+R I
Sbjct 1053 -RWAKENISSEVRTVHAAQGLSYKNVVYFRLTRTDNDLYTKRKLPYHLVAISRHTDKI-- 1109
Query 5876 IMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLS 5930
+ D F+ + + +D ++ +G + A S
Sbjct 1110 VYCTTKPEDSSDFSLSALKNTIKTS----------RDLTQEASGSESSYAVVFES 1154
>sp|P26627|R1AB_CVMJD Replicase polyprotein 1ab (Fragment) OS=Murine
coronavirus (strain defective JHM) OX=11143 GN=rep PE=3
SV=1
Length=500
Score = 46.6 bits (109), Expect = 0.010, Method: Composition-based stats.
Identities = 48/195 (25%), Positives = 76/195 (39%), Gaps = 21/195 (11%)
Query 1580 DVTKIKPHVNHEGKTFFVLPSDDT-LRSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQV 1638
D+ K++ + E +T P+D T AF+ ++ S S H K V
Sbjct 323 DIEKVEDSILSELQTELNAPADKTYEDVLAFDAIYSETLSAFYAVPSDETHFK------V 376
Query 1639 GGLTSIKWADNNCYLSSVLLALQQLEVKFNAPALQEAYYRARAGDAANFCALILAYSNKT 1698
G S NC+L S L+ +Q L ++F +Q+ + +AG F ++ + K+
Sbjct 377 CGFYSPAIERTNCWLRSTLIVMQSLPLEFKDLGMQKLWLSYKAGYDQCFVDKLVKSAPKS 436
Query 1699 VGEL--GDVRETMTHLLQHANLESAKRVLNVVCKHCGQKTTTLTGVEAVMYMGTLSYDNL 1756
+ G V + L S K N C CG L G++AV + G +
Sbjct 437 IILPQGGYVADFAYFFLSQ---CSFKVHANWRCLKCGM-ELKLQGLDAVFFYGDV----- 487
Query 1757 KTGVSIPCVCGRDAT 1771
VS C C A
Sbjct 488 ---VSHMCKCSFKAY 499
>sp|Q89AB2|RECD_BUCBP RecBCD enzyme subunit RecD OS=Buchnera aphidicola
subsp. Baizongia pistaciae (strain Bp) OX=224915 GN=recD
PE=3 SV=1
Length=618
Score = 46.2 bits (108), Expect = 0.011, Method: Composition-based stats.
Identities = 34/162 (21%), Positives = 66/162 (41%), Gaps = 20/162 (12%)
Query 5563 FSSNVANYQKVGM-----QKYSTLQGPPGTGKSHFAIGLALYYPSAR-----IVYTACSH 5612
F++N+ + QK+ + + + G PGTGK+ + + L I TA +
Sbjct 149 FNTNIDDTQKLAIILSIINNITFIIGGPGTGKTTIILKILLVLIRLHKKKINIKLTALTG 208
Query 5613 AAVDALCEKAL---KYLPIDKCSRIIPARARVECFD--KFKVNSTLEQYVFCTVNALPET 5667
A + L E K L + + + I + + K N + C N L
Sbjct 209 KAANRLSESIHENIKKLNLTEHEKNIFNQKTTTLHNLLDLKPNKSFNYS--CCKNKL--Y 264
Query 5668 TADIVVFDEISMATNYDLSVVNARL-RAKHYVYIGDPAQLPA 5708
++++ DE SM + + + + + +++GD QLP+
Sbjct 265 NLNLLIIDEASMIDITIMDKLISSIPKTTKIIFLGDYNQLPS 306
>sp|Q9YKD6|RDRP_TOMS1 Replicase large subunit OS=Tomato mosaic
virus (strain S-1) OX=138314 PE=3 SV=1
Length=1616
Score = 46.6 bits (109), Expect = 0.012, Method: Composition-based stats.
Identities = 73/407 (18%), Positives = 121/407 (30%), Gaps = 75/407 (18%)
Query 5572 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5631
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFEED---LILVPGRQAAEMIRRRA------NAS 872
Query 5632 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM----ATNYDLSV 5687
I+ + V D F + DE M N+ +
Sbjct 873 GIIVATKDNVRTVDSF----------LMNYGKGARCQFKRLFIDEGLMLHTGCVNF---L 919
Query 5688 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5747
V L YVY GD Q+P + G P +F + + T RCPA
Sbjct 920 VEMSLSDIAYVY-GDTQQIPYINRV--TGFPYPAHFAKL-----EVDEVETRRTTLRCPA 971
Query 5748 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5807
++ ++ Y+ + + + G + + S + + LT +
Sbjct 972 DVTHFLNQR-YEGHVMCTSSEKKSVSQEMVSGAASINPVSK------PLKGKILTFTQSD 1024
Query 5808 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAIT 5867
++A+ Y TV QG Y V + T T S I
Sbjct 1025 KEALLSRGYT------------DVHTVHEVQGETYADVSLVRLTPTPVSI--------IA 1064
Query 5868 RAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPT 5927
R +L +S L++ ++ + E V+ D K+ G
Sbjct 1065 RDSPHVLVSLSRHT--KSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVDAG-----TQX 1117
Query 5928 HLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
L VD FK L V P IS M F + + G +
Sbjct 1118 QLQVDSVFKNFNLFVATPKTGD-------ISDMQFYYDKCLPGNSTL 1157
>sp|P17766|POLG_PPVNA Genome polyprotein OS=Plum pox potyvirus
(isolate NAT) OX=12213 PE=3 SV=1
Length=3125
Score = 46.6 bits (109), Expect = 0.012, Method: Composition-based stats.
Identities = 58/332 (17%), Positives = 116/332 (35%), Gaps = 36/332 (11%)
Query 4814 DGNAAISDYDYYRYNLP---TMCDIRQLLFVVEVV-----DKYFDCYDGGCINANQVIVN 4865
+ +A + D +Y+ P D Q V+VV K F+ + + I +
Sbjct 2357 NKDAYVKDLM--KYSKPIVVGAVDCDQFERAVDVVISMLISKGFE--ECNYVTDPDDIFS 2412
Query 4866 NLDKSAGFPFNKWGKARLYYDSMSYEDQDALF-AYTKRNVI--PTITQMNLKYAISAKNR 4922
L+ A GK R Y++++S +D+++ A KR + + +LK + K +
Sbjct 2413 ALNMKAAVGALYSGKKRDYFENVSDQDKESFVRASCKRLFMGKKGVWNGSLKAELRPKEK 2472
Query 4923 ARTVAGVSICSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKTVYS 4976
S + + K+ + +G +KF GGW +LK +
Sbjct 2473 VEANKTRSFTAAPIDTLLGGKVCVDDFNNQFYSLNLHCPWSVGMTKFRGGWDKLLKALPE 2532
Query 4977 DVETPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEM 5035
G + D ++ P ++ + ++ LA L+N +++
Sbjct 2533 GWIYCDADGSQF---DSSLSPYLINAVLNIRLA----FMEEWDIGEQMLSNLYTEIVYTP 2585
Query 5036 VMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKI------ADKY 5088
+ G++ K G +SG +T N++ I + + D +
Sbjct 2586 IATPDGTIVKKFKGNNSGQPSTVVDNTLMVILAMTYSLLKLGHHPDTHDCICRYFVNGDD 2645
Query 5089 VRNLQHRLYECLYRNRDVDHEFVDEFYAYLRK 5120
+ H YE +Y + Y + K
Sbjct 2646 LVLAVHPAYESIYDELQEHFSQLGLNYTFTTK 2677
>sp|Q90069|POLG_SBMVG Genome polyprotein OS=Soybean mosaic virus
(strain G2) OX=103931 PE=3 SV=1
Length=3066
Score = 46.2 bits (108), Expect = 0.017, Method: Composition-based stats.
Identities = 47/279 (17%), Positives = 102/279 (37%), Gaps = 28/279 (10%)
Query 4805 ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF-----DCYDGGCINA 4859
K FF + +++ D+ + + ++ ++ + + + + YD + A
Sbjct 2352 AFKRGFFKYNKPVVLNEVDFQSFER-AVAGVKLMMMEFDFKECVYVTDPDEIYDSLNMKA 2410
Query 4860 NQVIVNNLDKSAGF--PFNKWGKARLYY---DSMSYEDQDALFAYTKRNVIPTITQMNLK 4914
V K + + + K RL Y + + Y ++ K + P K
Sbjct 2411 A-VGAQYKGKKQDYFSGMDSFDKERLLYLSCERLFYGEKGVWNGSLKAELRPIEKVQANK 2469
Query 4915 YAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTV 4974
T+ G +C N QF+ L +G +KFY GW +++++
Sbjct 2470 TRTFTAAPIDTLLGAKVCVDDFNNQFYSLNLT-------CPWTVGMTKFYRGWDKLMRSL 2522
Query 4975 YSDVETPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLS 5033
H G + D ++ P +L + VL + + L N A+++
Sbjct 2523 PDGWVYCHADGSQF---DSSLTPLLL----NAVLDVRSFFMEDWWVGREMLENLYAEIVY 2575
Query 5034 EMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5071
++ G+++ K G +SG +T N++ + +
Sbjct 2576 TPILAPDGTIFKKFRGNNSGQPSTVVDNTLMVVIALYYS 2614
>sp|Q5GS59|RLME_WOLTR Ribosomal RNA large subunit methyltransferase
E OS=Wolbachia sp. subsp. Brugia malayi (strain TRS) OX=292805
GN=rlmE PE=3 SV=1
Length=216
Score = 44.3 bits (103), Expect = 0.018, Method: Composition-based stats.
Identities = 36/152 (24%), Positives = 58/152 (38%), Gaps = 14/152 (9%)
Query 6850 DKGVAPG--TAVLRQWLPTGTLLVDSDLNDFVSDADSTLIG-DCATVHT------ANKWD 6900
D G +PG + V Q G +V D+ + + I D + T K+D
Sbjct 65 DLGASPGGWSQVASQ---KGVKVVAIDIKPVNTISGVKYIQYDINELETLRERFKDQKFD 121
Query 6901 LIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLY-KLM 6959
+I+SDM + ++ F K L GG VKI + + D Y +L
Sbjct 122 VILSDMAPESCGLKSLDHIRIMLLCEAALNFAKHFLNYGGKFVVKIFQGESDKDFYNELK 181
Query 6960 GHFSWWTAFVTNVNAS-SSEAFLIGANYLGKP 6990
F F + S S+E +L+G ++
Sbjct 182 KMFKIVKYFKPKSSRSESTEMYLVGLGFISNS 213
>sp|P13529|POLG_PPVD Genome polyprotein OS=Plum pox potyvirus
(strain D) OX=12212 PE=1 SV=2
Length=3141
Score = 45.8 bits (107), Expect = 0.021, Method: Composition-based stats.
Identities = 57/332 (17%), Positives = 115/332 (35%), Gaps = 36/332 (11%)
Query 4814 DGNAAISDYDYYRYNLP---TMCDIRQLLFVVEVV-----DKYFDCYDGGCINANQVIVN 4865
+ +A + D +Y+ P D Q V+VV K F+ + + I +
Sbjct 2358 NKDAYVKDLM--KYSKPIVVGAVDCDQFERAVDVVISMLISKGFE--ECNYVTDPDDIFS 2413
Query 4866 NLDKSAGFPFNKWGKARLYYDSMSYEDQDALF-AYTKRNVI--PTITQMNLKYAISAKNR 4922
L+ A GK R Y+ ++S +D+++ A KR + + +LK + K +
Sbjct 2414 ALNMKAAVGALYSGKKRDYFKNVSDQDKESFVRASCKRLFMGKKGVWNGSLKAELRPKEK 2473
Query 4923 ARTVAGVSICSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKTVYS 4976
S + + K+ + +G +KF GGW +L+ +
Sbjct 2474 VEANKTRSFTAAPIDTLLGGKVCVDDFNNQFYSLNLHCPWSVGMTKFRGGWDKLLRALPE 2533
Query 4977 DVETPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEM 5035
G + D ++ P ++ + ++ LA L+N +++
Sbjct 2534 GWIYCDADGSQF---DSSLSPYLINAVLNIRLA----FMEEWDIGEQMLSNLYTEIVYTP 2586
Query 5036 VMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKI------ADKY 5088
+ G++ K G +SG +T N++ I + + D +
Sbjct 2587 IATPDGTIVKKFKGNNSGQPSTVVDNTLMVILAMTYSLLKLGYHPDTHDCICRYFVNGDD 2646
Query 5089 VRNLQHRLYECLYRNRDVDHEFVDEFYAYLRK 5120
+ H YE +Y + Y + K
Sbjct 2647 LVLAVHPAYESIYDELQEHFSQLGLNYTFATK 2678
>sp|Q65399|POLG_BCMNN Genome polyprotein OS=Bean common mosaic
necrosis virus (strain NL-3) OX=500578 PE=2 SV=1
Length=3066
Score = 45.8 bits (107), Expect = 0.022, Method: Composition-based stats.
Identities = 53/280 (19%), Positives = 105/280 (38%), Gaps = 46/280 (16%)
Query 4823 DYYRYNLPTMCD------IRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFN 4876
D+++YN P M + + + V+++ F + + I ++L+ A
Sbjct 2360 DFFKYNKPVMLNEVNFEAFEKAVEGVKIMMIEFGFNECVYVTDPDDIYDSLNMKAAVGAQ 2419
Query 4877 KWGKARLYYDSMSYEDQDALFA-------YTKRNVIPTITQMNLK---YAISAKNRARTV 4926
GK + Y+ M D++ L Y ++ + + L+ + K R T
Sbjct 2420 YKGKKQDYFQDMDSFDKERLLFLSCERLFYGQKGIWNGSLKAELRPLEKVQANKTRTFTA 2479
Query 4927 A------GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVET 4980
A G +C N QF+ L +G +KFYGGW +++ +
Sbjct 2480 APIDTLLGAKVCVDDFNNQFYSFNLI-------CPWTVGMTKFYGGWDKLMRAL------ 2526
Query 4981 PHLMGWDYPKCDRAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVL-SEMVMC- 5038
P GW Y D + + + L+L + + + E + L +E+V
Sbjct 2527 PD--GWVYCHADGSQFDS--SLTPLLLNSVLSIRSFFMED-WWVGKEMLENLYAEIVYTP 2581
Query 5039 ----GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVN 5074
G+++ K G +SG +T N++ + + +
Sbjct 2582 ILTPDGTIFKKFRGNNSGQPSTVVDNTLMVVISMYYSCIK 2621
>sp|P17767|POLG_PPVRA Genome polyprotein OS=Plum pox potyvirus
(strain Rankovic) OX=12214 PE=2 SV=2
Length=3140
Score = 45.4 bits (106), Expect = 0.025, Method: Composition-based stats.
Identities = 57/332 (17%), Positives = 115/332 (35%), Gaps = 36/332 (11%)
Query 4814 DGNAAISDYDYYRYNLP---TMCDIRQLLFVVEVV-----DKYFDCYDGGCINANQVIVN 4865
+ +A + D +Y+ P D Q V+VV K F+ + + I +
Sbjct 2357 NKDAYVKDLM--KYSKPIVVGAVDCDQFERAVDVVISMLISKGFE--ECNYVTDPDDIFS 2412
Query 4866 NLDKSAGFPFNKWGKARLYYDSMSYEDQDALF-AYTKRNVI--PTITQMNLKYAISAKNR 4922
L+ A GK R Y+ ++S +D+++ A KR + + +LK + K +
Sbjct 2413 ALNMKAAVGALYSGKKRDYFKNVSDQDKESFVRASCKRLFMGKKGVWNGSLKAELRPKEK 2472
Query 4923 ARTVAGVSICSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKTVYS 4976
S + + K+ + +G +KF GGW +L+ +
Sbjct 2473 VEANKTRSFTAAPIDTLLGGKVCVDDFNNQFYSLNLHCPWSVGMTKFRGGWDKLLRALPE 2532
Query 4977 DVETPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEM 5035
G + D ++ P ++ + ++ LA L+N +++
Sbjct 2533 GWIYCDADGSQF---DSSLSPYLINAVLNIRLA----FMEEWDIGEQMLSNLYTEIVYTP 2585
Query 5036 VMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKI------ADKY 5088
+ G++ K G +SG +T N++ I + + D +
Sbjct 2586 IATPDGTIVKKFKGNNSGQPSTVVDNTLMVILAMTYSLLKLGYHPDTHDCICRYFVNGDD 2645
Query 5089 VRNLQHRLYECLYRNRDVDHEFVDEFYAYLRK 5120
+ H YE +Y + Y + K
Sbjct 2646 LVLAVHPAYESIYDELQEHFSQLGLNYTFATK 2677
>sp|P32270|DDA_BPT4 ATP-dependent DNA helicase dda OS=Enterobacteria
phage T4 OX=10665 GN=dda PE=1 SV=2
Length=439
Score = 45.0 bits (105), Expect = 0.027, Method: Composition-based stats.
Identities = 34/152 (22%), Positives = 58/152 (38%), Gaps = 20/152 (13%)
Query 5575 MQKYSTLQGPPGTGKSH---FAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5631
+ + T+ GP GTGK+ F I + I+ A +HAA +K L L +
Sbjct 24 KKHHVTINGPAGTGKTTLTKFIIEALISTGGTGIILAAPTHAA-----KKILSKLSGKEA 78
Query 5632 SRIIPARARVECFDKFKVNS-TLEQYVFCTVNALPETTAD-IVVFDEISMATNYDLSVVN 5689
S I K+N T E+ V +P+ +++ DE+SM ++
Sbjct 79 STI---------HSILKINPVTYEENVLFEQKEVPDLAKCRVLICDEVSMYDRKLFKILL 129
Query 5690 ARLRA-KHYVYIGDPAQLPAPRTLLTKGTLEP 5720
+ + + IGD Q+ + P
Sbjct 130 STIPPWCTIIGIGDNKQIRPVEPGENTAYISP 161
>sp|Q54PT1|GDAP2_DICDI Protein GDAP2 homolog OS=Dictyostelium
discoideum OX=44689 GN=gdap2 PE=3 SV=1
Length=568
Score = 45.0 bits (105), Expect = 0.031, Method: Composition-based stats.
Identities = 45/264 (17%), Positives = 92/264 (35%), Gaps = 38/264 (14%)
Query 972 RVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVN-----QFTGYLKLTDNVAIKCVDIVKE 1026
+++ +E + W ++ + + + P E + QF ++ + + DI
Sbjct 10 KIDYKEIKTWDQTEFDEKNLVNDKDKVPIENFHINGPIQFKIDTEINSRICLWMGDIC-- 67
Query 1027 AQSANPMVIVNAANIHLKHGGGVAGALNKATNGAMQKESDDYIKLNGPLTVGGSCLLSGH 1086
+ N IV + + L ++ + K M + I+ NG G S + SG
Sbjct 68 --NLNTDTIVYSNSKTLTESDTISDKIFKYGGSEMMND----IQKNGECRYGESIITSGG 121
Query 1087 NLA-KKCLHVVGPNLNA---GEDIQLLKAAYENFN------SQDILLAPLLSAGIFGAKP 1136
NL + +H V P N L + Y + + L +
Sbjct 122 NLPSRFVVHTVCPTYNPKYLSAAENALNSCYRSAFHLSMDVKSKSISFSTLHSEKRQFPS 181
Query 1137 LQSLQVCVQTVR-----------TQVYIAVN---DKALYEQVVMDYLDNLKPRVEAPKQE 1182
+ + ++T+R +V +A+N D LYEQ++ Y + ++ Q
Sbjct 182 VGGCHIALRTIRRFLEKPFSKSFEKVILAINTFEDLRLYEQMLPIYFPRNQQELK-FSQI 240
Query 1183 EPPNTEDSKTEEKSVVQKPVDVKP 1206
P + E V + + +
Sbjct 241 SLPKDVGDENGEAIVESRKIRIIE 264
>sp|Q83044|R1A_LIYV9 Replicase polyprotein 1a OS=Lettuce infectious
yellows virus (isolate United States/92) OX=651355 GN=ORF1a
PE=4 SV=1
Length=1873
Score = 45.0 bits (105), Expect = 0.032, Method: Composition-based stats.
Identities = 56/297 (19%), Positives = 103/297 (35%), Gaps = 51/297 (17%)
Query 5584 PPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVEC 5643
PPG GK+ L ++ A S+ V L + + L D I V+
Sbjct 1574 PPGAGKTTTIAKLMSKDLKNKVKCLALSYTKVGRL--ELIDKLKKDG---IEKPEKYVKT 1628
Query 5644 FDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDP 5703
+D F +N+ + VN DE+ M + ++ ++ GD
Sbjct 1629 YDSFLMNNDN---ILEIVNLYC---------DEVFMMHAGHFLTLLTKIAYQNGYCYGDV 1676
Query 5704 AQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK 5763
Q+P + + P Y + + + D + RCP + +S L
Sbjct 1677 NQIP----FINRDPYTPAYLSREFFRKQDLNYDTY---TYRCPLDTCYLLSNL------- 1722
Query 5764 AHKDKSAQCFKMFYKGVITHD----VSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5819
KD+ ++ GV + ++N I VV E P A +++ +
Sbjct 1723 --KDEMGNI--IYAGGVKNVNEVYPTIRSLNLFGINVVGEV----PVEYNAKYLTFTQDE 1774
Query 5820 NAVASKILGLP------TQTVDSSQGSEYDYVIFTQTT--ETAHSCNVNRFNVAITR 5868
+ + TV+ +QG + V + + ++N+F VAI+R
Sbjct 1775 KLNLQRHIDSQGGCRNAVSTVNEAQGCTFSEVNLVRLVQFDNPVMSDINQFVVAISR 1831
>sp|Q89249|RDRP_SBWMN Replicase large subunit OS=Soil-borne wheat
mosaic virus (strain United States/Nebraska/1981) OX=652673
GN=rep PE=3 SV=1
Length=1828
Score = 45.0 bits (105), Expect = 0.033, Method: Composition-based stats.
Identities = 57/309 (18%), Positives = 96/309 (31%), Gaps = 54/309 (17%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5636
+ + G PG GKS + L P +V A + L EK +K
Sbjct 1021 RITLRDGVPGCGKSTWI--LNNANPMKDMVLCV-GKEATEDLKEKFMKKHK--------- 1068
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
K T++ ++ + A V FDE MA + L AK
Sbjct 1069 -----CAESDLKRIRTVDSFLMHDYDKF---RAATVHFDEALMAHAGIVYFCADILGAKK 1120
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5756
+ GD Q+P + ++ +Y I ++ R P ++ ++
Sbjct 1121 VICQGDSQQIP---FINRVESITLQYAKL------AIDETEYVRLTYRSPVDVAHYLTKK 1171
Query 5757 -VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISP 5815
Y K+ + K+ S P R A +++
Sbjct 1172 SWYSGGRVTTKNSVLRSMKVVGPRDAKPMTSVHC--------------VPYHRDAQYLTF 1217
Query 5816 YNSQNAVASKIL----GLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVN------RFNVA 5865
S+ A K L + TV +QG +D VI + T + VA
Sbjct 1218 TQSEKADLYKALRAKGPVEVNTVHETQGKTFDDVIVVRLKTTENEIYPGGRKGQPYEIVA 1277
Query 5866 ITRAKIGIL 5874
TR + ++
Sbjct 1278 TTRHRRSLV 1286
>sp|Q84934|POLG_PPVSK Genome polyprotein OS=Plum pox potyvirus
(strain SK 68) OX=103927 PE=3 SV=1
Length=3140
Score = 45.0 bits (105), Expect = 0.034, Method: Composition-based stats.
Identities = 56/323 (17%), Positives = 111/323 (34%), Gaps = 34/323 (11%)
Query 4823 DYYRYNLP---TMCDIRQLLFVVEVV-----DKYFDCYDGGCINANQVIVNNLDKSAGFP 4874
D +Y+ P D Q ++VV K F+ + + I + L+ A
Sbjct 2364 DLMKYSKPIVVGAVDCEQFERALDVVISMLISKGFE--ECNYVTDPDDIFSALNMKAAVG 2421
Query 4875 FNKWGKARLYYDSMSYED-QDALFAYTKRNVI--PTITQMNLKYAISAKNRARTVAGVSI 4931
GK R Y+ + S +D +D + A KR + + +LK + K + S
Sbjct 2422 ALYSGKKRDYFKNASEQDKEDFIKASCKRLFMGKKGVWNGSLKAELRPKEKVEANKTRSF 2481
Query 4932 CSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKTVYSDVETPHLMG 4985
+ + K+ + +G +KF GGW +L+ + G
Sbjct 2482 TAAPIDTLLGGKVCVDDFNNQFYSLNLHCPWSVGMTKFRGGWDKLLRALPDGWIYCDADG 2541
Query 4986 WDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMC-GGSLY 5043
+ D ++ P ++ + ++ LA L+N +++ + G++
Sbjct 2542 SQF---DSSLSPYLINAVLNIRLA----FMEEWDIGEQMLSNLYTEIVYTPIATPDGTIV 2594
Query 5044 VKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKI------ADKYVRNLQHRLY 5097
K G +SG +T N++ I + + D ++ + H Y
Sbjct 2595 KKFKGNNSGQPSTVVDNTLMVILAMTYSLLKLGYHPDTHECICRYFVNGDDLVLAVHPAY 2654
Query 5098 ECLYRNRDVDHEFVDEFYAYLRK 5120
E +Y + Y + K
Sbjct 2655 ESMYDELQEHFSQLGLNYTFTTK 2677
>sp|P89676|RDRP_TOMK2 Replicase large subunit OS=Tomato mosaic
virus (strain Kazakh K2) OX=138312 PE=3 SV=1
Length=1616
Score = 45.0 bits (105), Expect = 0.036, Method: Composition-based stats.
Identities = 70/407 (17%), Positives = 120/407 (29%), Gaps = 75/407 (18%)
Query 5572 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5631
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFEED---LILVPGRQAAEMIRRRA------NAS 872
Query 5632 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM----ATNYDLSV 5687
I+ + V D F + DE M N+ + +
Sbjct 873 GIIVATKDNVRTVDSF----------LMNYGKGARCQFKRLFIDEGLMLHTGCVNFLVEM 922
Query 5688 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5747
+ VY GD Q+P + G P +F + + T RCPA
Sbjct 923 SLCDIAY---VY-GDTQQIPYINRV--TGFPYPAHFAKL-----EVDEVETRRTTLRCPA 971
Query 5748 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5807
++ ++ Y+ + + + G + + S + + LT +
Sbjct 972 DVTHFLNQR-YEGHVMCTSSEKKSVSQEMVSGAASINPVSK------PLKGKILTFTQSD 1024
Query 5808 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAIT 5867
++A+ Y TV QG Y V + T T S I
Sbjct 1025 KEALLSRGY------------ADVHTVHEVQGETYADVSLVRLTPTPVSI--------IA 1064
Query 5868 RAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPT 5927
R +L +S L++ ++ + E V+ D K+ G
Sbjct 1065 RDSPHVLVSLSRHT--KSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVDAG-----TQX 1117
Query 5928 HLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
L VD FK L V P IS M F + + G +
Sbjct 1118 QLQVDSVFKNFNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTL 1157
>sp|Q83045|R1AB_LIYV9 Replicase polyprotein 1ab OS=Lettuce infectious
yellows virus (isolate United States/92) OX=651355 PE=3
SV=2
Length=2379
Score = 45.0 bits (105), Expect = 0.038, Method: Composition-based stats.
Identities = 56/297 (19%), Positives = 103/297 (35%), Gaps = 51/297 (17%)
Query 5584 PPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVEC 5643
PPG GK+ L ++ A S+ V L + + L D I V+
Sbjct 1574 PPGAGKTTTIAKLMSKDLKNKVKCLALSYTKVGRL--ELIDKLKKDG---IEKPEKYVKT 1628
Query 5644 FDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDP 5703
+D F +N+ + VN DE+ M + ++ ++ GD
Sbjct 1629 YDSFLMNNDN---ILEIVNLYC---------DEVFMMHAGHFLTLLTKIAYQNGYCYGDV 1676
Query 5704 AQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK 5763
Q+P + + P Y + + + D + RCP + +S L
Sbjct 1677 NQIP----FINRDPYTPAYLSREFFRKQDLNYDTY---TYRCPLDTCYLLSNL------- 1722
Query 5764 AHKDKSAQCFKMFYKGVITHD----VSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQ 5819
KD+ ++ GV + ++N I VV E P A +++ +
Sbjct 1723 --KDEMGNI--IYAGGVKNVNEVYPTIRSLNLFGINVVGEV----PVEYNAKYLTFTQDE 1774
Query 5820 NAVASKILGLP------TQTVDSSQGSEYDYVIFTQTT--ETAHSCNVNRFNVAITR 5868
+ + TV+ +QG + V + + ++N+F VAI+R
Sbjct 1775 KLNLQRHIDSQGGCRNAVSTVNEAQGCTFSEVNLVRLVQFDNPVMSDINQFVVAISR 1831
>sp|Q9Q1T8|RDRP_TOMK1 Replicase large subunit OS=Tomato mosaic
virus (strain Kazakh K1) OX=138311 PE=3 SV=2
Length=1616
Score = 45.0 bits (105), Expect = 0.038, Method: Composition-based stats.
Identities = 70/407 (17%), Positives = 120/407 (29%), Gaps = 75/407 (18%)
Query 5572 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5631
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFEED---LILVPGRQAAEMIRRRA------NAS 872
Query 5632 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM----ATNYDLSV 5687
I+ + V D F + DE M N+ + +
Sbjct 873 GIIVATKDNVRTVDSF----------LMNYGKGARCQFKRLFIDEGLMLHTGCVNFLVEM 922
Query 5688 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5747
+ VY GD Q+P + G P +F + + T RCPA
Sbjct 923 SLCDIAY---VY-GDTQQIPYINRV--TGFPYPAHFAKL-----EVDEVETRRTTLRCPA 971
Query 5748 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5807
++ ++ Y+ + + + G + + S + + LT +
Sbjct 972 DVTHFLNQR-YEGHVMCTSSEKKSVSQEMVSGAASINPVSK------PLKGKILTFTQSD 1024
Query 5808 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAIT 5867
++A+ Y TV QG Y V + T T S I
Sbjct 1025 KEALLSRGY------------ADVHTVHEVQGETYADVSLVRLTPTPVSI--------IA 1064
Query 5868 RAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPT 5927
R +L +S L++ ++ + E V+ D K+ G
Sbjct 1065 RDSPHVLVSLSRHT--KSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVDAG-----TQX 1117
Query 5928 HLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
L VD FK L V P IS M F + + G +
Sbjct 1118 QLQVDSVFKNFNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTL 1157
>sp|P03587|RDRP_TOML Replicase large subunit OS=Tomato mosaic
virus (strain L) OX=12252 PE=1 SV=2
Length=1616
Score = 45.0 bits (105), Expect = 0.040, Method: Composition-based stats.
Identities = 70/407 (17%), Positives = 120/407 (29%), Gaps = 75/407 (18%)
Query 5572 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5631
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFEED---LILVPGRQAAEMIRRRA------NAS 872
Query 5632 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM----ATNYDLSV 5687
I+ + V D F + DE M N+ + +
Sbjct 873 GIIVATKDNVRTVDSF----------LMNYGKGARCQFKRLFIDEGLMLHTGCVNFLVEM 922
Query 5688 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5747
+ VY GD Q+P + G P +F + + T RCPA
Sbjct 923 SLCDIAY---VY-GDTQQIPYINRV--TGFPYPAHFAKL-----EVDEVETRRTTLRCPA 971
Query 5748 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5807
++ ++ Y+ + + + G + + S + + LT +
Sbjct 972 DVTHFLNQR-YEGHVMCTSSEKKSVSQEMVSGAASINPVSK------PLKGKILTFTQSD 1024
Query 5808 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAIT 5867
++A+ Y TV QG Y V + T T S I
Sbjct 1025 KEALLSRGY------------ADVHTVHEVQGETYADVSLVRLTPTPVSI--------IA 1064
Query 5868 RAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPT 5927
R +L +S L++ ++ + E V+ D K+ G
Sbjct 1065 RDSPHVLVSLSRHT--KSLKYYTVVMDPLVSIIRDLERVSSYLLDMYKVDAG-----TQX 1117
Query 5928 HLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
L VD FK L V P IS M F + + G +
Sbjct 1118 QLQVDSVFKNFNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTL 1157
>sp|P21231|POLG_SBMVN Genome polyprotein OS=Soybean mosaic virus
(strain N) OX=12223 PE=1 SV=2
Length=3066
Score = 44.7 bits (104), Expect = 0.053, Method: Composition-based stats.
Identities = 47/279 (17%), Positives = 102/279 (37%), Gaps = 28/279 (10%)
Query 4805 ELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYF-----DCYDGGCINA 4859
K FF + +++ D+ + + ++ ++ + + + + YD + A
Sbjct 2352 AFKRDFFKYNKPVVLNEVDFQSFER-AVAGVKLMMMEFDFKECVYVTDPDEIYDSLNMKA 2410
Query 4860 NQVIVNNLDKSAGF--PFNKWGKARLYY---DSMSYEDQDALFAYTKRNVIPTITQMNLK 4914
V K + + + K RL Y + + Y ++ K + P K
Sbjct 2411 A-VGAQYKGKKQDYFSGMDSFDKERLLYLSCERLFYGEKGVWNGSLKAELRPIEKVQANK 2469
Query 4915 YAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTV 4974
T+ G +C N QF+ L +G +KFY GW +++++
Sbjct 2470 TRTFTAAPIDTLLGAKVCVDDFNNQFYSLNLT-------CPWTVGMTKFYRGWDKLMRSL 2522
Query 4975 YSDVETPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLS 5033
H G + D ++ P +L + VL + + L N A+++
Sbjct 2523 PDGWVYCHADGSQF---DSSLTPLLL----NAVLDVRSFFMEDWWVGREMLENLYAEIVY 2575
Query 5034 EMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTA 5071
++ G+++ K G +SG +T N++ + +
Sbjct 2576 TPILAPDGTIFKKFRGNNSGQPSTVVDNTLMVVIAMYYS 2614
>sp|Q73L97|RLME_TREDE Ribosomal RNA large subunit methyltransferase
E OS=Treponema denticola (strain ATCC 35405 / DSM 14222
/ CIP 103919 / JCM 8153 / KCTC 15104) OX=243275 GN=rlmE PE=3
SV=1
Length=199
Score = 42.4 bits (98), Expect = 0.071, Method: Composition-based stats.
Identities = 41/155 (26%), Positives = 59/155 (38%), Gaps = 18/155 (12%)
Query 6850 DKGVAPG--TAVLRQWL------------PTGTLLVDSDLNDFVSDADSTLIGDCATVHT 6895
D G APG T + ++L P + + D LN F D G +V
Sbjct 47 DLGAAPGSWTVYVLRFLNKEGRVTAVDLKPLDSSVYDERLNFFQGDMFDK--GIIKSVKE 104
Query 6896 ANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITE-HSWNAD 6954
+D +I D T + T + G + +++L GGS VKI +
Sbjct 105 LGPYDAVICDAAPATTGNKTVDTARSSGLVELALYYAQEQLKQGGSFVVKIFQGGDQQIH 164
Query 6955 LYKLMGHFSWWTAFVTNVNASSS-EAFLIGANYLG 6988
L L F AF SSS E +LIG ++ G
Sbjct 165 LNNLRKCFKTARAFKPEACRSSSFETYLIGLDFKG 199
>sp|Q73IS9|RLME_WOLPM Ribosomal RNA large subunit methyltransferase
E OS=Wolbachia pipientis wMel OX=163164 GN=rlmE PE=3 SV=1
Length=192
Score = 42.0 bits (97), Expect = 0.079, Method: Composition-based stats.
Identities = 33/152 (22%), Positives = 56/152 (37%), Gaps = 15/152 (10%)
Query 6850 DKGVAPG--TAVLRQWLPTGTLLVDSDLN--------DFVSDADSTLIGDCATVHTANKW 6899
D G +PG + V Q G +V D+ +F+ K+
Sbjct 40 DLGASPGGWSQVASQ---KGANVVALDIKPMNAINGVEFIQCDIINEFEILREKFKDQKF 96
Query 6900 DLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADL-YKL 6958
D+I+SDM + ++ F K L+ GG+ VKI + + D +L
Sbjct 97 DVILSDMAPESCGLKSLDHIRIMLLCEAALNFAKHFLSHGGTFVVKIFQGESDKDFCNEL 156
Query 6959 MGHFSWWTAFVTNVNAS-SSEAFLIGANYLGK 6989
F F + S S+E +L+ ++G
Sbjct 157 KKMFKTVKYFKPKSSRSESTEMYLVSLGFIGS 188
>sp|P17765|POLG_BYMV Genome polyprotein OS=Bean yellow mosaic
virus OX=12197 PE=3 SV=2
Length=3056
Score = 43.9 bits (102), Expect = 0.084, Method: Composition-based stats.
Identities = 39/231 (17%), Positives = 80/231 (35%), Gaps = 20/231 (9%)
Query 4863 IVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPT---ITQMNLKYAISA 4919
I++ L+ A GK + ++ +S E D + + + + +LK +
Sbjct 2383 ILSALNMKAAMGALYSGKKKDHFSEISEEKFDNILQASCERLYSGRMGVWNGSLKAELRP 2442
Query 4920 KNRARTVAGVSICSTMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKT 4973
+ + S + + K+ + +G +KFYGGW +L +
Sbjct 2443 QEKVLANKTRSFTAAPIDTLLAGKVCVDDFNNKFYSLHLKIPSTVGITKFYGGWDRLLDS 2502
Query 4974 VYSDVETPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVL 5032
+ G + D ++ P +L + + L L N +++
Sbjct 2503 LPDGWVYCDADGSQF---DSSLTPYLLNAVLEMRL----RLMEEWDLGEQMLKNLYTEIV 2555
Query 5033 SEMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGN 5082
++ G++ K G +SG +T N++ I A L GN
Sbjct 2556 YTPILTPDGTIVKKFKGNNSGQPSTVVDNTLMVIMAVYYAAEK--LGIKGN 2604
>sp|Q5PAN0|RLME_ANAMM Ribosomal RNA large subunit methyltransferase
E OS=Anaplasma marginale (strain St. Maries) OX=234826
GN=rlmE PE=3 SV=1
Length=201
Score = 41.6 bits (96), Expect = 0.11, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 40/97 (41%), Gaps = 2/97 (2%)
Query 6896 ANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADL 6955
K+D+++SDM H ++ + + L GGS KI + + +
Sbjct 92 DRKFDVVLSDMAPKSCGHRQVDHANIINLCEMALDLAVEFLRSGGSFVTKILQGEYEQEF 151
Query 6956 YKLMG-HFSWWTAFVTNVNAS-SSEAFLIGANYLGKP 6990
+ + +F+ T F + S SSE +L+G +
Sbjct 152 RRSLQYYFASVTYFKPKSSRSESSEIYLVGTKFKNPE 188
>sp|B9KIP4|RLME_ANAMF Ribosomal RNA large subunit methyltransferase
E OS=Anaplasma marginale (strain Florida) OX=320483 GN=rlmE
PE=3 SV=1
Length=201
Score = 41.6 bits (96), Expect = 0.11, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 40/97 (41%), Gaps = 2/97 (2%)
Query 6896 ANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADL 6955
K+D+++SDM H ++ + + L GGS KI + + +
Sbjct 92 DRKFDVVLSDMAPKSCGHRQVDHANIINLCEMALDLAVEFLRSGGSFVTKILQGEYEQEF 151
Query 6956 YKLMG-HFSWWTAFVTNVNAS-SSEAFLIGANYLGKP 6990
+ + +F+ T F + S SSE +L+G +
Sbjct 152 RRSLQYYFASVTYFKPKSSRSESSEIYLVGTKFKNPE 188
>sp|P45612|UVRD_MYCCT Probable DNA helicase II homolog OS=Mycoplasma
capricolum subsp. capricolum (strain California kid /
ATCC 27343 / NCTC 10154) OX=340047 GN=uvrD PE=3 SV=2
Length=722
Score = 43.1 bits (100), Expect = 0.13, Method: Composition-based stats.
Identities = 19/103 (18%), Positives = 39/103 (38%), Gaps = 7/103 (7%)
Query 5666 ETTADIVVFDEISMATNYDLSVVN-ARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFN 5724
D V+ DE S++ + H +GDP Q T+ + + +
Sbjct 216 RNAYDYVLVDEFQDTNELQFSLIKFLTINTNHLTVVGDPDQ-----TIYSWRGAKLDIIL 270
Query 5725 SVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKD 5767
+ + + L R +I+D ++ + +NK + HK+
Sbjct 271 NFNKTYSNAI-SIVLNQNYRSTKQILDISNSFIKNNKFREHKE 312
>sp|Q00020|1A_BBMV Replication protein 1a OS=Broad bean mottle
virus OX=12301 GN=ORF1a PE=3 SV=1
Length=966
Score = 42.7 bits (99), Expect = 0.16, Method: Composition-based stats.
Identities = 43/237 (18%), Positives = 79/237 (33%), Gaps = 41/237 (17%)
Query 5648 KVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLP 5707
KV T + + + LPE ++ DE + L V + + GD Q+
Sbjct 738 KVVRTADSAIM---HGLPECHR--LLVDEAGLLHYGQLLAVADLCKCSEVLAFGDTEQIS 792
Query 5708 APRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALV---------Y 5758
T +Y N + RCP ++V V L Y
Sbjct 793 FKS---RDATFRMKYCNI------EYDKRDIVSKTFRCPQDVVSAVKILKRKCANRSSKY 843
Query 5759 DNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNS 5818
+ + + K + + +IN+ + + +LT A + A +
Sbjct 844 NGWVSSSKVEKSLSKSRIV----------SINQVSMEKHKFYLTMTEADKAA--LCSRAK 891
Query 5819 QNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN----VAITRAKI 5871
+ + +TV +QG D+V+ + T C++ + VA+TR K
Sbjct 892 DVGLDKTWVESNMETVHEAQGKAVDHVVLVRLKSTK--CDLFKSEEYCLVALTRHKR 946
>sp|O71188|R1A_GLRV3 Replicase protein 1a OS=Grapevine leafroll-associated
virus 3 (isolate United States/NY1) OX=651354 GN=1a
PE=3 SV=2
Length=2233
Score = 42.7 bits (99), Expect = 0.17, Method: Composition-based stats.
Identities = 53/332 (16%), Positives = 111/332 (33%), Gaps = 47/332 (14%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5636
+Y PPG GK+ + + P++ TA ++ D I+ +
Sbjct 1930 EYKCYNAPPGGGKTTTLVDEFVKSPNSTATITANVGSSED-----------INMAVK--- 1975
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
+ + ++ VN + V+ DE+ M L + A
Sbjct 1976 -----KRDPNLEGLNSATTVNSRVVNFIVRGMYKRVLVDEVHMMHQGLLQLGVFATGASE 2030
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5756
++ GD Q+P + + + +++ ++ RCP ++ +S++
Sbjct 2031 GLFFGDINQIP----FINREKVFRMDCAVFVPKKESV---VYTSKSYRCPLDVCYLLSSM 2083
Query 5757 VYDNKLKAHKDKSAQCFKM-FYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISP 5815
+ +C+ G V S RP IG + N V++
Sbjct 2084 TVRG--------TEKCYPEKVVSGKDKPVVRSLSKRP-IGTTDDVAEINAD----VYLCM 2130
Query 5816 YNSQNAVASKIL-----GLPTQTVDSSQGSEY-DYVIF-TQTTETAHSCNVNRFNVAITR 5868
+ + + L P TV +QG + D V+F T+ + + V ++R
Sbjct 2131 TQLEKSDMKRSLKGKGKETPVMTVHEAQGKTFSDVVLFRTKKADDSLFTKQPHILVGLSR 2190
Query 5869 AKIGILCIMSDRDLYDKLQFTSLEIPRRNVAT 5900
++ L DK+ + ++V+
Sbjct 2191 HTRSLVYAALSSKLDDKVGTYISDASPQSVSD 2222
>sp|P35928|POLR_ELV RNA replicase polyprotein OS=Erysimum latent
virus OX=12152 PE=3 SV=1
Length=1748
Score = 42.7 bits (99), Expect = 0.17, Method: Composition-based stats.
Identities = 51/220 (23%), Positives = 74/220 (34%), Gaps = 47/220 (21%)
Query 5658 FCTVNALPETTADIVVFDEISMATN--YDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTK 5715
F T + A+I+V DEI DLS++ K + +GDP Q T
Sbjct 923 FSTWESALLKHAEILVIDEIYKLPRGYLDLSLIADP-TVKLVILLGDPLQGEYHSTSAHS 981
Query 5716 GTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKM 5775
L + + RL+ I D + R P + S CF
Sbjct 982 SNLRLS--SEIPRLLPFI--DYYCYWSYRVPKCVAKLFS---------------LPCF-- 1020
Query 5776 FYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAV-ASKILGLPTQTV 5834
P G ++ L P+ V NS + V S+ G T+
Sbjct 1021 ---------------NPSEGFIKTTLDFFPSANNLV-----NSHSVVHISEACGWNAVTI 1060
Query 5835 DSSQGSEY-DYVIFTQTTETAHSCNVNRFNVAITRAKIGI 5873
SSQG + D TA N VA+TR++ G+
Sbjct 1061 SSSQGCTFSDPAFIHLDRNTALLSPSNCL-VALTRSRSGV 1099
>sp|Q9RT63|RECD2_DEIRA ATP-dependent RecD2 DNA helicase OS=Deinococcus
radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871
/ CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM
B-1422 / R1) OX=243230 GN=recD2 PE=1 SV=1
Length=715
Score = 42.7 bits (99), Expect = 0.17, Method: Composition-based stats.
Identities = 32/142 (23%), Positives = 47/142 (33%), Gaps = 25/142 (18%)
Query 5571 QKVGMQKYSTLQGPPGTGKSHFAIGLA--LYYPSARIVYTACSHAAVDALCE-KALKYLP 5627
Q G + L G PGTGKS +A + A + A L E
Sbjct 349 QLAG-HRLVVLTGGPGTGKSTTTKAVADLAESLGLEVGLCAPTGKAARRLGEVTGRTAST 407
Query 5628 IDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATN-YDLS 5686
+ + P R N L D+++ DE+SM + LS
Sbjct 408 VHRLLGYGPQGFR--------------------HNHLEPAPYDLLIVDEVSMMGDALMLS 447
Query 5687 VVNARLRAKHYVYIGDPAQLPA 5708
++ A + +GD QLP
Sbjct 448 LLAAVPPGARVLLVGDTDQLPP 469
>sp|O71189|R1AB_GLRV3 Replicase polyprotein 1ab OS=Grapevine leafroll-associated
virus 3 (isolate United States/NY1) OX=651354
GN=1a-1b PE=3 SV=3
Length=2772
Score = 42.7 bits (99), Expect = 0.19, Method: Composition-based stats.
Identities = 53/332 (16%), Positives = 111/332 (33%), Gaps = 47/332 (14%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5636
+Y PPG GK+ + + P++ TA ++ D I+ +
Sbjct 1930 EYKCYNAPPGGGKTTTLVDEFVKSPNSTATITANVGSSED-----------INMAVK--- 1975
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
+ + ++ VN + V+ DE+ M L + A
Sbjct 1976 -----KRDPNLEGLNSATTVNSRVVNFIVRGMYKRVLVDEVHMMHQGLLQLGVFATGASE 2030
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5756
++ GD Q+P + + + +++ ++ RCP ++ +S++
Sbjct 2031 GLFFGDINQIP----FINREKVFRMDCAVFVPKKESV---VYTSKSYRCPLDVCYLLSSM 2083
Query 5757 VYDNKLKAHKDKSAQCFKM-FYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISP 5815
+ +C+ G V S RP IG + N V++
Sbjct 2084 TVRG--------TEKCYPEKVVSGKDKPVVRSLSKRP-IGTTDDVAEINAD----VYLCM 2130
Query 5816 YNSQNAVASKIL-----GLPTQTVDSSQGSEY-DYVIF-TQTTETAHSCNVNRFNVAITR 5868
+ + + L P TV +QG + D V+F T+ + + V ++R
Sbjct 2131 TQLEKSDMKRSLKGKGKETPVMTVHEAQGKTFSDVVLFRTKKADDSLFTKQPHILVGLSR 2190
Query 5869 AKIGILCIMSDRDLYDKLQFTSLEIPRRNVAT 5900
++ L DK+ + ++V+
Sbjct 2191 HTRSLVYAALSSKLDDKVGTYISDASPQSVSD 2222
>sp|P39369|YJHR_ECOLI Putative uncharacterized protein YjhR OS=Escherichia
coli (strain K12) OX=83333 GN=yjhR PE=5 SV=1
Length=338
Score = 41.6 bits (96), Expect = 0.22, Method: Composition-based stats.
Identities = 25/98 (26%), Positives = 40/98 (41%), Gaps = 20/98 (20%)
Query 5805 PAWRKAVFISPYNSQNAVASKILG------------LPTQTVDSSQGSEYDYVIFTQTTE 5852
P ++ ++P+++Q L L TV S QG+E V+F+
Sbjct 45 PLYKVVGVVTPFSAQVNAIKMSLRKLEINGKDEQGLLTVGTVHSLQGAERAIVLFSPV-Y 103
Query 5853 TAH------SCNVNRFNVAITRAKIGILCIMSDRDLYD 5884
+ H N NVA++RAK L + D DL +
Sbjct 104 SKHEDGRFLDSNSTILNVAVSRAKDSFL-VFGDMDLIE 140
>sp|Q65674|TGB1_BNYVS Movement protein TGB1 OS=Beet necrotic yellow
vein virus (isolate Japan/S) OX=652670 GN=ORF4 PE=3 SV=1
Length=384
Score = 41.6 bits (96), Expect = 0.29, Method: Composition-based stats.
Identities = 47/309 (15%), Positives = 95/309 (31%), Gaps = 78/309 (25%)
Query 5577 KYSTLQGPPGTGKSHFAIGL-ALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRII 5635
+ + G PG GKS L + ++V ++ + L +D
Sbjct 117 RVGIVLGAPGVGKSTSIKNLLDKFGAKHKMVLCLPFSQLLEGVFAGRLDTFLVDD----- 171
Query 5636 PARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAK 5695
+FC ++ + ++ DE++ ++ V+ L K
Sbjct 172 ---------------------LFC--RSVGYGKYNTMLVDEVTRVHMCEILVLAGHLGVK 208
Query 5696 HYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSA 5755
+ + GDPAQ L +N ++ G A+++++ +
Sbjct 209 NVICFGDPAQ------GLNYKAGSAVNYN--FPIIAECYASRRFGKA---TADLINSSNG 257
Query 5756 ----LVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5811
+V +N++K C K+ V
Sbjct 258 GGKPVVGNNEVKDSWTFEELCGKIL------------------------------DMSTV 287
Query 5812 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYV--IFTQTTETAHSCNVNRFNVAITRA 5869
++ +Q + + + + G YD V I + A C+ N V +TRA
Sbjct 288 LVATRETQKFLLED--NIESILYSDAHGQTYDVVTIILEDEFDDAAICDPNVRAVLLTRA 345
Query 5870 KIGILCIMS 5878
+ G + M
Sbjct 346 RKGGMIKMG 354
>sp|Q64962|RDRP_ASPVP RNA replication polyprotein OS=Apple stem
pitting virus (isolate PA66) OX=651356 GN=ORF1 PE=3 SV=1
Length=2183
Score = 42.0 bits (97), Expect = 0.31, Method: Composition-based stats.
Identities = 47/317 (15%), Positives = 104/317 (33%), Gaps = 49/317 (15%)
Query 5564 SSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKAL 5623
S + + V +K + G G GKS P I + + + +++
Sbjct 1357 SKLIP--ELVHERKLIMILGTFGCGKSSLFKKFIEKSPGKAITFVSPRRSLAESI----- 1409
Query 5624 KYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNY 5683
D + + + D V + ++++ E VV DEI +
Sbjct 1410 ---NHDLGLARVGGKKTGKSKDLKNVRVKTFELFILHLDSIKEGH--TVVIDEIQLFPPG 1464
Query 5684 DLSVVNARLRAKH-YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTC 5742
+ ++ L+ + GDP Q ++ G +
Sbjct 1465 YIDLIILGLKPNVNIIIAGDPCQ---------------SDYDCSSDRHIFAGSE------ 1503
Query 5743 RRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGV-----V 5797
++I+ +S Y + + + ++ +FY + + + + + +
Sbjct 1504 ----SDIMRILSGRSYKFNILSQRFRN----PVFYGRLPCNLNKTRLTLDEEEYTLWDSI 1555
Query 5798 REFLTRNPAWRKAVFISPYNSQNAVASKI-LGLPTQTVDSSQGSEYDYVIFTQTTETAHS 5856
+EF V +S + + VA+ + L + T S G + T E+A +
Sbjct 1556 QEFSMMGRKDCPVVLVSSFEEKKIVAAHLGLKMKCITYGESTGLNFQKGAILVTYESALT 1615
Query 5857 CNVNRFNVAITRAKIGI 5873
+ R+ A++R I
Sbjct 1616 SD-RRWWTALSRFSHDI 1631
>sp|A0A0S2T050|RDRP_TBRFV Replicase large subunit OS=Tomato brown
rugose fruit virus (isolate TOBRFV/Tomato/Jordan/Tom1-Jo/2015)
OX=2654645 PE=3 SV=1
Length=1615
Score = 41.6 bits (96), Expect = 0.41, Method: Composition-based stats.
Identities = 76/410 (19%), Positives = 124/410 (30%), Gaps = 81/410 (20%)
Query 5572 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5631
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSKVNFEED---LILVPGKQAAEMIKRRA------NAS 872
Query 5632 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM----ATNYDLSV 5687
I R V D F +N Y T + DE M N+ +S+
Sbjct 873 GIIQATRDNVRTVDSFIMN-----YGKGT-----RCQFKRLFIDEGLMLHTGCVNFLVSM 922
Query 5688 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5747
+ VY GD Q+P + G P +F + + T RCPA
Sbjct 923 SLCEIAY---VY-GDTQQIPYINRV--SGFPYPAHFAKI-----EVDEVETRRTTLRCPA 971
Query 5748 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5807
+I ++ Y+ + + G + +++P G V F +
Sbjct 972 DITHYLNRR-YEGYVMCTSSVKKSVSQEMVSGAAMIN---PVSKPLNGKVLTFTQ---SD 1024
Query 5808 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---NVNRFNV 5864
++A+ Y TV QG Y V + T T S + V
Sbjct 1025 KEALLSRGYT------------DVHTVHEVQGETYADVSLVRLTPTPVSIIAGDSPHVLV 1072
Query 5865 AITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQ 5924
A++R L++ ++ + E ++ D K+ G
Sbjct 1073 ALSRHT-------------QTLKYYTVVMDPLVSIIRDLEKLSSYLLDMYKVDAG----- 1114
Query 5925 APTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
L VD FK L V P IS M F + + G M
Sbjct 1115 TQXQLQVDSVFKGSNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTM 1157
>sp|Q08534|R1AB_BYVU Replicase polyprotein 1ab OS=Beet yellows
virus (isolate Ukraine) OX=478555 GN=1a-1b PE=1 SV=2
Length=3094
Score = 41.6 bits (96), Expect = 0.46, Method: Composition-based stats.
Identities = 49/300 (16%), Positives = 97/300 (32%), Gaps = 46/300 (15%)
Query 5584 PPGTGKSHFAIGLA--LYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARV 5641
PPG GK+ I + + ++ TA + ++ + + K + +D+ + R R+
Sbjct 2250 PPGGGKTTTLIKVFCETFSKVNSLILTA-NKSSREEILAKVNRI-VLDEGDTPLQTRDRI 2307
Query 5642 ECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIG 5701
D + +N+ T ++ DE M + + G
Sbjct 2308 LTIDSYLMNNRG-------------LTCKVLYLDECFMVHAGAAVACIEFTKCDSAILFG 2354
Query 5702 DPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPD--MFLGTCRRCPAEIVDTVSALVYD 5759
D Q + G + L + + + ++ RCP ++
Sbjct 2355 DSRQ-------IRYGRCSELDTAVLSDLNRFVDDESRVYGEVSYRCPWDVCA-------- 2399
Query 5760 NKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREF--LTRNPAWRKAVFIS-PY 5816
L K+ + G + V + + EF LT + +K + S
Sbjct 2400 -WLSTFYPKTVATTNLVSAGQSSMQVREIESVDDVEYSSEFVYLTMLQSEKKDLLKSFGK 2458
Query 5817 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTT---ETAHSCNVNRFNVAITRAKIGI 5873
S+++V TV +QG Y V +T + N VA++R +
Sbjct 2459 RSRSSVEKP----TVLTVHEAQGETYRKVNLVRTKFQEDDPFRSE-NHITVALSRHVESL 2513
>sp|Q9ILI5|NS1AB_TASV2 Non-structural polyprotein 1AB OS=Turkey
astrovirus 2 OX=246343 GN=ORF1 PE=3 SV=2
Length=1638
Score = 41.2 bits (95), Expect = 0.48, Method: Composition-based stats.
Identities = 49/301 (16%), Positives = 99/301 (33%), Gaps = 25/301 (8%)
Query 4822 YDYYRYNLPTMCDIRQLLFVV---EVVDKYFDCYDGGCINANQVIVNNLDKSAGFP-FNK 4877
++ + Y+ P + FV+ +V + D I N++ + +P F
Sbjct 1213 FEKFHYHDPVDFVEQYAEFVLLCDNMVLREHDYMANSNITPIMSTEKNVNSTPAYPKFQA 1272
Query 4878 WGKARLYYDSMSYEDQDALF---AYTKRNVI--PTITQMNLKYAISAKNRARTVAGVSIC 4932
+ Y + +++ + R + + LK + R +
Sbjct 1273 YDSEAEYLEDCGWQEYLDVVSDPETINRRPLWWCFLKNEVLKREKIEDSDIRMILCTDPI 1332
Query 4933 STMTNRQFHQKLLKSIAA-TRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKC 4991
T F Q + T + +G + F+GG ++ +Y D + + D+ +
Sbjct 1333 FTRIGAMFEQDQNNRMKQQTEIRSAQVGWTPFFGGLDRRVRRLYGDGDRYFV-EMDWTRY 1391
Query 4992 DRAMPNML----RIMASLVLARKHNTCCNLSHRFYRLANECAQVLSE--MVMCGGSLYVK 5045
D +P L R + L H T + RL N + L E +++ G +
Sbjct 1392 DGTIPKSLFWRIRQIRFFFLHDSHKT-----PKMRRLYNWYVKNLLEKIILLPTGEVCQV 1446
Query 5046 PGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRD 5105
G SG +T N++ N+ G + + LQ Y +
Sbjct 1447 KKGNPSGQFSTTVDNNMINVWLTTFEVSYLFFKQRGRLPTE---KELQENCSMICYGDDR 1503
Query 5106 V 5106
+
Sbjct 1504 L 1504
>sp|Q01500|POLG_PEMVC Genome polyprotein OS=Pepper mottle virus
(isolate California) OX=31737 PE=1 SV=1
Length=3068
Score = 41.2 bits (95), Expect = 0.52, Method: Composition-based stats.
Identities = 41/249 (16%), Positives = 92/249 (37%), Gaps = 29/249 (12%)
Query 4838 LLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALF 4897
L + + + C I + I L+ + GK + Y++ + ED+ +
Sbjct 2372 LELLYTQIHGFRKC---SYITDEEEIFKALNITTAVGAMYGGKKKEYFEKFTTEDKAEIL 2428
Query 4898 AYTKRNVIPTIT------QMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKL----LKS 4947
+++ + T + LK + +K + + + + K+ L +
Sbjct 2429 ---RQSCLRLYTGKLGVWEWALKAELRSKEKIEANKTRTFTAAPIDTLLGGKVCVDDLNN 2485
Query 4948 IAATRGATV--VIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAM--PNMLRIMA 5003
++ +G +KFYGGW +L + + GW Y D + ++ +
Sbjct 2486 QFYSKNIECCWTVGMTKFYGGWDKLLTALPA--------GWIYCDADGSQFDSSLTPYLI 2537
Query 5004 SLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMC-GGSLYVKPGGTSSGDATTAYANSV 5062
+ VL ++ + + L N +++ + G++ K G +SG +T NS+
Sbjct 2538 NAVLTIRYAFMEDWDIGYKMLQNLYTEIIYTPISTPDGTIVKKFRGNNSGQPSTVVDNSL 2597
Query 5063 FNICQAVTA 5071
+ A
Sbjct 2598 MVVLAMHYA 2606
>sp|Q84687|RDRP_PCV87 Replicase large subunit OS=Peanut clump
virus (isolate 87/TGTA2) OX=652837 GN=rep PE=3 SV=2
Length=1672
Score = 41.2 bits (95), Expect = 0.56, Method: Composition-based stats.
Identities = 64/358 (18%), Positives = 108/358 (30%), Gaps = 85/358 (24%)
Query 5547 YVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIV 5606
+ ++ +YP+L Q K + G PG GKS + + R +
Sbjct 834 FNKLVLVYPSL----------PKTQL----KVRLIDGVPGCGKSTWILS---NCDLDRQI 876
Query 5607 YTACSHAAVDAL----CEKALKYLPIDKCSRII------PARARVECFDKFKVNSTLEQY 5656
A A D L EK ++ R + P R F
Sbjct 877 VLAEGREATDDLRRRFTEKGFPKKRCEERVRTVHSFMLKPLSRRFNSFH----------- 925
Query 5657 VFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKG 5716
FDE MA + + L A+ + GD Q+P + +
Sbjct 926 -----------------FDEALMAHAGMIYICGRMLNAREVICQGDSKQIPFIN-RVEQI 967
Query 5717 TLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMF 5776
+L+ FN V R + RCP +IV Y NK K ++
Sbjct 968 SLKYSSFNVVEREH--------VRKTYRCPLDIV------YYLNKKKYYRGD------DI 1007
Query 5777 YKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDS 5836
T ++ L + P + + + + G TV
Sbjct 1008 VGYSKTTHSVDTKSKSSGFTSLVKLPKEPVHYLTFLQAEKEEVSKHLAGVKGATVSTVHE 1067
Query 5837 SQGSEYDYVIFTQTTETAHSCNVNRF------NVAITRAKIGIL--CIMSDRDLYDKL 5886
+QG ++ V + T + V +TR ++ ++ DR LY+ +
Sbjct 1068 AQGKTFERVNLVRLKMTDNELYPGGAKSEPYTIVGLTRHTRSLVYYSVVEDR-LYEDI 1124
>sp|Q58889|PRS2_METJA Putative 26S proteasome regulatory subunit
homolog MJ1494 OS=Methanocaldococcus jannaschii (strain ATCC
43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) OX=243232
GN=MJ1494 PE=3 SV=2
Length=371
Score = 40.4 bits (93), Expect = 0.59, Method: Composition-based stats.
Identities = 33/124 (27%), Positives = 46/124 (37%), Gaps = 11/124 (9%)
Query 5494 VQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAP-----TLVPQEHYV 5548
V+ G+Y F+ D ++ +TY G TS TV L P T + +
Sbjct 69 VKEGDYLFDNSILPD-YAFKVISTYPKEGGMI---TSETVFKLQTPKKVLRTQFKKAKFS 124
Query 5549 RITGLYPTLNISDEFSSNVANYQKVGM--QKYSTLQGPPGTGKSHFAIGLALYYPSARIV 5606
I G + N + G K GPPGTGK+ A LA S+ I+
Sbjct 125 EIIGQEEAKKKCRIIMKYLENPKLFGEWAPKNVLFYGPPGTGKTLMARALATETNSSFIL 184
Query 5607 YTAC 5610
A
Sbjct 185 VKAP 188
>sp|P27752|1A_CCMV Replication protein 1a OS=Cowpea chlorotic
mottle virus OX=12303 GN=ORF1a PE=2 SV=1
Length=958
Score = 40.8 bits (94), Expect = 0.61, Method: Composition-based stats.
Identities = 61/318 (19%), Positives = 107/318 (34%), Gaps = 51/318 (16%)
Query 5568 ANYQKVGMQ---------KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDAL 5618
ANYQ + K S G G GK+ + A + + + + +
Sbjct 658 ANYQVLSKNTDSLKAPSCKISLCDGVAGCGKTTA---IKSASNIAEHLVVTANKKSAEDV 714
Query 5619 CEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEIS 5678
E P + S I FKV T + + + LP ++ DE
Sbjct 715 REAL---FPHNPSSEIA-----------FKVIRTADSALM---HGLPRCKR--LLVDEAG 755
Query 5679 MATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMF 5738
+ L V A + + + GD Q+ T +Y + ++ D+
Sbjct 756 LLHYGQLLAVAALCKCQSVLAFGDTEQISFKS---RDATFRLKYGD-----LQFDSRDIV 807
Query 5739 LGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVR 5798
T RCP +++ V L K ++ +K K + + Q+ + R
Sbjct 808 TET-WRCPQDVISAVQTL----KRGGNRTSKYLGWKSHSKVSRSISHKEIASPLQVTLSR 862
Query 5799 E-FLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC 5857
E F KA +S + + +TV +QG D+ + + T C
Sbjct 863 EKFYLTMTQADKAALVSRAKDFPELDKAWIEKHIKTVHEAQGVSVDHAVLVRLKSTK--C 920
Query 5858 NVNRFN----VAITRAKI 5871
++ + VA+TR KI
Sbjct 921 DLFKTEEYCLVALTRHKI 938
>sp|Q4FRM3|RS20_PSYA2 Small ribosomal subunit protein bS20 OS=Psychrobacter
arcticus (strain DSM 17307 / VKM B-2377 / 273-4)
OX=259536 GN=rpsT PE=3 SV=1
Length=88
Score = 37.0 bits (84), Expect = 0.64, Method: Composition-based stats.
Identities = 18/82 (22%), Positives = 38/82 (46%), Gaps = 6/82 (7%)
Query 3933 AYATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQ--RK----LEKMADQAM 3986
A A++ ++ + +++ K ++ A + D DAA + +K L++MAD+ +
Sbjct 7 ARKRARQNTKRRQNSASQRSMVRTYLKRVDAAIAAKDYDAATEAYKKAVPVLDRMADKGI 66
Query 3987 TQMYKQARSEDKRAKVTSAMQT 4008
K AR + + K +Q
Sbjct 67 LHKNKAARRKSRLNKTIKGLQA 88
>sp|P20234|POLG_OMV Genome polyprotein (Fragment) OS=Ornithogalum
mosaic virus OX=12204 PE=3 SV=1
Length=1136
Score = 40.8 bits (94), Expect = 0.67, Method: Composition-based stats.
Identities = 52/279 (19%), Positives = 98/279 (35%), Gaps = 56/279 (20%)
Query 4816 NAAISDYDYYRYNLPTMCD----IRQLLFVVEVVDKYFDCYDGGC--INANQVIVNNLDK 4869
A + D +Y+ P + I+ V+ + D C + + + NL+
Sbjct 432 EAFVKDIM--KYSKPIVLGEVDFIKFEEGYNNVLRMFHDIGFEKCEYVTDSMEVYKNLNL 489
Query 4870 SAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQM-NLKYAI---SAKNRART 4925
A GK + Y++ MS ++ L VI + ++ + K+ + S K R
Sbjct 490 KAAVGAMYTGKKQQYFEGMSEDEIHQL-------VIASCFRLWSGKFGVWNGSLKAELRP 542
Query 4926 VAGVSICSTMTNR-------------------QFHQKLLKSIAATRGATVVIGTSKFYGG 4966
+ V C T T QF+ K L A +G K+Y G
Sbjct 543 LEKVQACKTRTFTAAPLDTLLGAKVCVDDFNAQFYDKHLT-------APWTVGICKYYKG 595
Query 4967 WHNMLKTVYSDVETPHLMGWDYPKCDRAM--PNMLRIMASLVLARKHNTCCNLSHRFYRL 5024
W + + GW Y D + ++ + + VL + + L
Sbjct 596 WDTFMNKLPE--------GWLYCDADGSQFDSSLTPFLINSVLRLRLEFMEDWDIGARML 647
Query 5025 ANECAQVLSEMVMC-GGSLYVKPGGTSSGDATTAYANSV 5062
+N +++ + G++ K G +SG +T N++
Sbjct 648 SNLYTEIIYTPIATPDGTVVKKFRGNNSGQPSTVVDNTL 686
>sp|Q5UQ32|RPO6_MIMIV DNA-directed RNA polymerase subunit 6 OS=Acanthamoeba
polyphaga mimivirus OX=212035 GN=MIMI_R209 PE=3
SV=1
Length=396
Score = 40.4 bits (93), Expect = 0.67, Method: Composition-based stats.
Identities = 21/80 (26%), Positives = 35/80 (44%), Gaps = 6/80 (8%)
Query 927 PPDEEEEDDAECEEEEIDETCEHEYGTEDDYQGLPLEFGASAETVRVEEEEEEDWLDD-- 984
PD+E +D+ + ID E EY T+ D + P++ E E+EED ++D
Sbjct 62 APDDELGEDSATLD--IDPDDEAEYDTDGDEKFNPIDEMGEPEDPDDPSEQEEDEVEDLG 119
Query 985 --TTEQSEIEPEPEPTPEEP 1002
+ EIE + +
Sbjct 120 SEDVDNVEIEDDAADIEDLD 139
>sp|O11436|POLG_RGMVD Genome polyprotein OS=Ryegrass mosaic virus
(isolate Denmark/Danish) OX=652106 PE=3 SV=1
Length=3086
Score = 40.8 bits (94), Expect = 0.70, Method: Composition-based stats.
Identities = 32/138 (23%), Positives = 54/138 (39%), Gaps = 18/138 (13%)
Query 4937 NRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCD--RA 4994
N QF+ LK +G +KF+G W++ L + GWDY D R
Sbjct 2448 NNQFYAAHLK-------GPWTVGITKFFGRWNDFLSELPP--------GWDYFDADGSRF 2492
Query 4995 MPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMC-GGSLYVKPGGTSSGD 5053
++ + + VL + N + L N +++ + GS+ K G +SG
Sbjct 2493 DSSLTPFLLNAVLNIRKKFMINWAFGQRCLGNLYTEIIYTPIATPDGSVVKKMRGNNSGQ 2552
Query 5054 ATTAYANSVFNICQAVTA 5071
+T N++ I A
Sbjct 2553 PSTVVDNTIMVIIAMQYA 2570
>sp|Q9YQ08|RDRP_TMVB Replicase large subunit OS=Tobacco mosaic
virus (strain B935A) OX=138309 PE=3 SV=1
Length=1616
Score = 40.8 bits (94), Expect = 0.71, Method: Composition-based stats.
Identities = 70/410 (17%), Positives = 125/410 (30%), Gaps = 81/410 (20%)
Query 5572 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5631
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFDED---LILVPGKQAAEMIRRRA------NSS 872
Query 5632 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM----ATNYDLSV 5687
I+ + V+ D F +N + DE M N+ +++
Sbjct 873 GIIVATKDNVKTVDSFMMNFGKST----------RCQFKRLFIDEGLMLHTGCVNFLVAM 922
Query 5688 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5747
+ VY GD Q+P + G P +F + + T RCPA
Sbjct 923 SLCEIAY---VY-GDTQQIPYINRV--SGFPYPAHFAKL-----EVDEVETRRTTLRCPA 971
Query 5748 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5807
++ ++ Y+ + + + G + S + +I LT +
Sbjct 972 DVTHYLNRR-YEGFVMSTSSVKKSVSQEMVGGAAVINPISKPSHGKI------LTFTQSD 1024
Query 5808 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---NVNRFNV 5864
++A+ Y+ TV QG Y V + T T S + V
Sbjct 1025 KEALLSRGYS------------DVHTVHEVQGETYSDVSLVRLTPTPVSIIAGDSPHVLV 1072
Query 5865 AITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQ 5924
A++R L++ ++ + E ++ D K+ G
Sbjct 1073 ALSRHTCS-------------LKYYTVVMDPLVSIIRDLEKLSSYLSDMYKVDAG----- 1114
Query 5925 APTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
L +D FK L V P IS M F + + G M
Sbjct 1115 TQXQLQIDSVFKGSNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTM 1157
>sp|B0R461|HTR6_HALS3 Transducer protein Htr6 OS=Halobacterium
salinarum (strain ATCC 29341 / DSM 671 / R1) OX=478009 GN=htr6
PE=1 SV=1
Length=789
Score = 40.4 bits (93), Expect = 0.73, Method: Composition-based stats.
Identities = 27/218 (12%), Positives = 68/218 (31%), Gaps = 7/218 (3%)
Query 830 TVWEVQGYKNVRITFELDERVDKVLNEKCSVYTVESGTEVTEFACVVAEAVVKTLQPVSD 889
++ EV D + ++ E+ + + ++ + +SD
Sbjct 523 SIQEVAASSATVAETAADAVERGEAGRDAAESAIDDMAEIESLSADAVDQILALQERMSD 582
Query 890 LLTNMGIDLDEWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEH 949
+ + D + E + + F E +D AE ++ +
Sbjct 583 IGDIIEFITDIAEQTNMLALNANIEAARADKDGDGFAVVANEVKDLAEETKQAAADIESE 642
Query 950 EYGTEDDYQGLPLEFGASAE-------TVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEP 1002
+ + + A++E TV ED +D + + E E+
Sbjct 643 IQAVQAETDETVADIRATSEHIDDGVSTVERAAAAIEDTVDAIEDANHGIQEISDATEDQ 702
Query 1003 VNQFTGYLKLTDNVAIKCVDIVKEAQSANPMVIVNAAN 1040
+ ++ D+VA + ++A+ + +A+
Sbjct 703 ADATQSVVRRVDDVADISQHVTEDAEQVSAAAEEQSAS 740
>sp|P15576|NU1M_LEITA NADH-ubiquinone oxidoreductase chain 1 OS=Leishmania
tarentolae OX=5689 GN=ND1 PE=3 SV=1
Length=313
Score = 39.7 bits (91), Expect = 0.84, Method: Composition-based stats.
Identities = 28/234 (12%), Positives = 72/234 (31%), Gaps = 14/234 (6%)
Query 3552 IVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHK-- 3609
I + + +T+ I + + + F + + T+ + C+M
Sbjct 67 ISFDIIYLIGAMIITACCIFLGWFYFPIGFILLLDTGFTLTVMLCVHVFCSMFSTFFVGC 126
Query 3610 HAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELA------------DTSLSGYRLK 3657
F F+ S +F+++ +++ + ++ + +
Sbjct 127 FLFSSCFVYLSAMRTMFFSIISESGIFLLYTTIYSLDYFSFFGIKDVCVGQIYITNFYIA 186
Query 3658 DCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISV 3717
+ + V ++L + +D + +IT + ++ I+ L +
Sbjct 187 GVLFISVFWVSMLLDGLKLPFDYMECESELVAGLITELSGFFFVLYSVLEINHILLTTLL 246
Query 3718 TSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYF 3771
++ I F A I+ Y ++ + FL Y C F
Sbjct 247 FASLCFGGLFICFKAILILIFGFFYPRVIGYRLKITTAQAFILIFLFYMCVLMF 300
>sp|Q2FQC0|KUP_METHJ Probable potassium transport system protein
Kup OS=Methanospirillum hungatei JF-1 (strain ATCC 27890
/ DSM 864 / NBRC 100397 / JF-1) OX=323259 GN=kup PE=3 SV=1
Length=611
Score = 40.0 bits (92), Expect = 0.86, Method: Composition-based stats.
Identities = 24/133 (18%), Positives = 45/133 (34%), Gaps = 8/133 (6%)
Query 2998 VDAMNLIANIFTPLVQPVGALDVSASVV--------AGGIIAILVTCAAYYFMKFRRVFG 3049
++I T + P+ +D ++ + ++ I V C F R+
Sbjct 313 SGIFSIIYQAITTHLLPMLPVDYTSDELRTQIYINTVNWLLCIAVICVLLIFQYSERLAS 372
Query 3050 EYNHVVAANALLFLMSFTILCLVPAYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMF 3109
Y V + + L G+ + L YF + VS + H + ++
Sbjct 373 AYGLAVTGTMSITGSFMIAIFLQRRKYLYMGIALIVTLVDITYFLSTVSKITHGGYLSLV 432
Query 3110 SPIVPFWITAIYV 3122
+PF I IY
Sbjct 433 IAAIPFTIVIIYT 445
>sp|F4J0C0|AATPA_ARATH AAA-ATPase At3g28600 OS=Arabidopsis thaliana
OX=3702 GN=At3g28600 PE=2 SV=1
Length=477
Score = 40.0 bits (92), Expect = 0.87, Method: Composition-based stats.
Identities = 17/43 (40%), Positives = 23/43 (53%), Gaps = 2/43 (5%)
Query 5557 LNISDEFSSNVANYQKVGM--QKYSTLQGPPGTGKSHFAIGLA 5597
LN FS+ Y+K+G ++ L GPPGTGKS +A
Sbjct 217 LNDLAAFSNGKEYYKKIGKAWKRGYLLHGPPGTGKSTMIAAMA 259
>sp|Q6XW15|POLG_BTMV Genome polyprotein OS=Beet mosaic virus OX=114921
PE=3 SV=1
Length=3085
Score = 40.4 bits (93), Expect = 0.88, Method: Composition-based stats.
Identities = 46/268 (17%), Positives = 99/268 (37%), Gaps = 28/268 (10%)
Query 4823 DYYRYNLPTMCDIRQLLFVVEVVDKYFDCYD----GGC--INANQVIVNNLDKSAGFPFN 4876
D+ +Y P + + V + + G C + I ++L+ A
Sbjct 2365 DFLKYAGPITVGVVNTNSFEDAVASVINMLEDLDYGECAYVTDPDSIFDSLNMKAAVGAL 2424
Query 4877 KWGKARLYYDSMSYEDQDALFAYTKRNVIPT---ITQMNLKYAISAKNRARTVAGVSICS 4933
GK + Y++ ++ +++ L + + + +LK + K + + +
Sbjct 2425 YKGKKKEYFEQLNTTEREDLLRLSCERLYEGKMGVWNGSLKAELRPKEKLEQNKTRTFTA 2484
Query 4934 TMTNRQFHQKLLKSIAATR------GATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWD 4987
+ K+ R +G +KFYGGW+ +L+ + P GW
Sbjct 2485 APIDTLLGGKVCVDDFNNRFYSLNLKGPWSVGMTKFYGGWNELLQKL------PD--GWI 2536
Query 4988 YPKCDRA-MPNMLR--IMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMC-GGSLY 5043
Y D + + L ++ ++V R+H + L N +++ ++ G++
Sbjct 2537 YCDADGSQFDSSLTPYLINAVVQIREH-FMEDWEIGRTMLRNFYTEIVYTPILTPDGTIV 2595
Query 5044 VKPGGTSSGDATTAYANSVFNICQAVTA 5071
K G +SG +T N++ I A
Sbjct 2596 KKFKGNNSGQPSTVVDNTLMVILAMHYA 2623
>sp|P19723|POLG_PRSVP Genome polyprotein (Fragment) OS=Papaya
ringspot virus (strain P / mutant HA 5-1) OX=31730 PE=3 SV=1
Length=675
Score = 40.0 bits (92), Expect = 0.95, Method: Composition-based stats.
Identities = 44/240 (18%), Positives = 83/240 (35%), Gaps = 37/240 (15%)
Query 4917 ISAKNRARTVA------GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNM 4970
++ K R+ T A G +C N F+ K ++ +G +KFY GW
Sbjct 32 LAKKTRSFTAAPLDTLLGAKVCVDDFNNWFYSKNME-------CPWTVGMTKFYKGWDEF 84
Query 4971 LKTVYSDVETPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRLANECA 5029
L+ G + D ++ P +L + S+ L + L N
Sbjct 85 LRKFPDGWVYCDADGSQF---DSSLTPYLLNAVLSIRLWAMED----WDIGEQMLKNLYG 137
Query 5030 QVLSEMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNK----- 5083
++ ++ G++ K G +SG +T N++ + A A T +
Sbjct 138 EITYTPILTPDGTIVKKFKGNNSGQPSTVVDNTLMVLITMYYALRKAGYDTKTQEDMCVF 197
Query 5084 -IADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKH------FSMM---ILSDDAVV 5133
I + H +E + + + Y + ++H + M IL DD +
Sbjct 198 YINGDDLCIAIHPDHEHVLDSFSSSFAELGLKYDFAQRHRNKQNLWFMSHRGILIDDIYI 257
>sp|Q91ZC6|MRGA6_MOUSE Mas-related G-protein coupled receptor
member A6 OS=Mus musculus OX=10090 GN=Mrgpra6 PE=2 SV=2
Length=301
Score = 39.7 bits (91), Expect = 0.97, Method: Composition-based stats.
Identities = 22/151 (15%), Positives = 48/151 (32%), Gaps = 10/151 (7%)
Query 3643 WLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDD-----AARRVWTLMNVITLVYK 3697
+ ++G + + L ++ + R + +W L ++ ++Y+
Sbjct 84 YTFRVLLYIAGLNMLSAISIERCLSVMCPIWYRCHRPEHTSTVMCAMIWVLSLLLCILYR 143
Query 3698 VYYG-----NALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNT 3752
+ G D + + + VV + LA C L T
Sbjct 144 YFCGFLDTKYEDDYGCLAMNFLTTAYLMFLFVVLCVSSLALLARLFCGAGRMKLTRLYVT 203
Query 3753 LQCIMLVYCFLGYCCCCYFGLFCLLNRYFRL 3783
+ +LV+ G C Y+ L + F +
Sbjct 204 ITLTLLVFLLCGLPCGFYWFLLSKIKNVFSV 234
>sp|Q0IE10|UVRB_SYNS3 UvrABC system protein B OS=Synechococcus
sp. (strain CC9311) OX=64471 GN=uvrB PE=3 SV=1
Length=679
Score = 40.0 bits (92), Expect = 1.0, Method: Composition-based stats.
Identities = 52/295 (18%), Positives = 99/295 (34%), Gaps = 21/295 (7%)
Query 5574 GMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSR 5633
G ++Y TL G GTGK+ F + + + A + LC + ++ P +
Sbjct 29 GGERYQTLLGATGTGKT-FTMANVIAQTGRPALVLAHNKTLAAQLCNELREFFPHNAVEY 87
Query 5634 IIPARARVECFDKFKVNSTLEQYVFCTVNALP--ETTADIVVFDEISMATNYDLSVVNAR 5691
I + V+ T + +A +F+ + +S +
Sbjct 88 FISYYDYYQPEAYVPVSDTYIAKTASINEEIDMLRHSATRSLFERRDVIVVASISCIYGL 147
Query 5692 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5751
Y+ P + TL +G+L N R G F R ++++
Sbjct 148 GIPSEYLKAAVPFK--VGETLNLRGSLRDLVNNQYSRNDTEAGRGRF-----RVKGDVLE 200
Query 5752 TVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5811
A YD++L + + + Y T ++ +++ I + F+T P R
Sbjct 201 IGPA--YDDRLVRVELFGDEVEAIRYVDPTTGEILQSLDAISIYPAKHFVT--PKERLND 256
Query 5812 FISPYNSQNAVASKILG-----LPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR 5861
+ S+ + L L Q ++ Q + YD + Q N R
Sbjct 257 AVKAIRSELKERLEFLNGEGKLLEAQRLE--QRATYDLEMLQQIGYCNGVENYAR 309
>sp|P36304|POLR_KYMVJ RNA replicase polyprotein OS=Kennedya yellow
mosaic virus (strain Jervis bay) OX=36392 PE=3 SV=1
Length=1874
Score = 40.0 bits (92), Expect = 1.1, Method: Composition-based stats.
Identities = 41/233 (18%), Positives = 80/233 (34%), Gaps = 40/233 (17%)
Query 5645 DKFKVN---STLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRA-KHYVYI 5700
+++K + + + FCT + I+V DEI L + + + +
Sbjct 1035 NEWKKDMNLPASQAFRFCTWESSLLKQTKILVIDEIYKLPRGYLDLCILADPCLELVIIL 1094
Query 5701 GDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDN 5760
GDP Q + + + + RL+ I D + R P+ I D S
Sbjct 1095 GDPLQ--GEYHSTSPHSSNHQLQSETTRLLPFI--DHYCWWTYRVPSHIADLFS------ 1144
Query 5761 KLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQN 5820
++S ++M + + + +V T N
Sbjct 1145 --VPSFNRSEGHYQMAVR------TADSYTPGHFNLVNSVATAN---------------- 1180
Query 5821 AVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGI 5873
A LG P T+ +SQG + + + + + + VA+TR+ +G+
Sbjct 1181 --AVIQLGFPATTISASQGVTHHNRVTILLDKHSRLLSPSNTLVALTRSTVGV 1231
>sp|P19724|POLG_PRSVW Genome polyprotein (Fragment) OS=Papaya
ringspot virus (strain W) OX=12207 PE=3 SV=1
Length=675
Score = 40.0 bits (92), Expect = 1.1, Method: Composition-based stats.
Identities = 44/240 (18%), Positives = 83/240 (35%), Gaps = 37/240 (15%)
Query 4917 ISAKNRARTVA------GVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNM 4970
++ K R+ T A G +C N F+ K ++ +G +KFY GW
Sbjct 32 LAKKTRSFTAAPLDTLLGAKVCVDDFNNWFYSKNME-------CPWTVGMTKFYKGWDEF 84
Query 4971 LKTVYSDVETPHLMGWDYPKCDRAM-PNMLRIMASLVLARKHNTCCNLSHRFYRLANECA 5029
L+ G + D ++ P +L + S+ L + L N
Sbjct 85 LRKFPDGWVYCDADGSQF---DSSLTPYLLNAVLSIRLWAMED----WDIGEQMLKNLYG 137
Query 5030 QVLSEMVMC-GGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNK----- 5083
++ ++ G++ K G +SG +T N++ + A A T +
Sbjct 138 EITYTPILTPDGTIVKKFKGNNSGQPSTVVDNTLMVLITMYYALRKAGYDTKTQEDMCVF 197
Query 5084 -IADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKH------FSMM---ILSDDAVV 5133
I + H +E + + + Y + ++H + M IL DD +
Sbjct 198 YINGDDLCIAIHPDHEHVLDSFSRSFAELGLKYDFTQRHRNKQNLWFMSHRGILIDDIYI 257
>sp|P28726|1A_PSVJ Replication protein 1a OS=Peanut stunt virus
(strain J) OX=12314 GN=ORF1a PE=3 SV=1
Length=1005
Score = 40.0 bits (92), Expect = 1.1, Method: Composition-based stats.
Identities = 55/307 (18%), Positives = 102/307 (33%), Gaps = 55/307 (18%)
Query 5578 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPA 5637
S + G G GK+ L + P+ ++ TA +A D + C+ +
Sbjct 717 ISLVDGVAGCGKTTAIKKL--FQPATDLIVTANKKSAQDVRMALFGASDSKEACTFV--- 771
Query 5638 RARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHY 5697
T + + N +PE + V+ DE+ + L V ++L+A
Sbjct 772 -------------RTADSILL---NDVPEVSR--VLVDEVVLLHFGQLCAVMSKLKAVRA 813
Query 5698 VYIGDPAQL-----PAPRTLLTKGTL--EPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIV 5750
+ GD Q+ A + L E ++ R + + P + R + +
Sbjct 814 ICFGDSEQIAFGSRDASFDMRRSTILPDESSTSDTTFRSPQDVVPLVT-----RMAGKAL 868
Query 5751 DTVSALVYDNKL---KAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5807
+ Y L K S +C ++ + R ++T A
Sbjct 869 PRGAKSKYSRWLSQSKVLNSVSQRCIP-------------SVALVDMDESRFYITMTQAD 915
Query 5808 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC--NVNRFNVA 5865
+ A+ + + S +TV SQG D+V + T + VA
Sbjct 916 KAALITRA--KELQMPSSFYDNKIKTVHESQGISEDHVTLVRLKSTKCDLFKSFPYCLVA 973
Query 5866 ITRAKIG 5872
+TR K+
Sbjct 974 LTRHKVS 980
>sp|Q88920|RDRP_TVCV Replicase large subunit OS=Turnip vein-clearing
virus OX=29272 PE=3 SV=1
Length=1601
Score = 40.0 bits (92), Expect = 1.2, Method: Composition-based stats.
Identities = 61/410 (15%), Positives = 121/410 (30%), Gaps = 70/410 (17%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5636
K + G PG GK+ I + + A + +A ++ I
Sbjct 821 KVILVDGVPGCGKTKEIIEKVNFSED---LILVPGKEASKMIIRRA------NQAGVIRA 871
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
+ V D F ++ + + DE M ++ + +
Sbjct 872 DKDNVRTVDSFLMHPS-------------RRVFKRLFIDEGLMLHTGCVNFLLLLSQCDV 918
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5756
GD Q+P + P +F + K + RCPA++ ++
Sbjct 919 AYVYGDTKQIPFICRVANFPY--PAHFAKLVADEKEVRRVTL-----RCPADVTYFLNKK 971
Query 5757 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5816
YD + +G A+N + + + LT A + + Y
Sbjct 972 -YDGAVMCTSAVERSVKAEVVRGK------GALNPITLPLEGKILTFTQADKFELLEKGY 1024
Query 5817 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKIGILCI 5876
TV QG Y+ + T T I+ A +L
Sbjct 1025 K------------DVNTVHEVQGETYEKTAIVRLTSTPLEI--------ISSASPHVLVA 1064
Query 5877 MSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTHLSVDIKFK 5936
++ ++ ++ + + E ++ D ++ G+ L +D F+
Sbjct 1065 LTRHT--TCCKYYTVVLDPMVNVISEMEKLSNFLLDMYRVEAGVQ-----YQLQIDAVFR 1117
Query 5937 TEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVR 5986
L V PK +R M F + + G + + ++R
Sbjct 1118 DSNLFVQ---TPKSGDWRD----MQFYYDALLPGNSTILNEFDAVTMNLR 1160
>sp|Q3KNA1|MRGB2_MOUSE Mas-related G-protein coupled receptor
member B2 OS=Mus musculus OX=10090 GN=Mrgprb2 PE=2 SV=2
Length=338
Score = 39.3 bits (90), Expect = 1.2, Method: Composition-based stats.
Identities = 28/203 (14%), Positives = 64/203 (32%), Gaps = 12/203 (6%)
Query 3588 FLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELA 3647
FL + A + L +LC + + ++ + ++ ++
Sbjct 61 FLGIRMHTNAFTVYILNLAMADFLYLCSQF---VICLLIAFYIFYSIDINIPLVLYVVPI 117
Query 3648 DTSLSGYRLKDCVMYASALVLLILMTARTVYDD-----AARRVWTLMNVITLVYKVYYGN 3702
LSG + + L ++ + R +W + ++ L+ G
Sbjct 118 FAYLSGLSILSTISIERCLSVIWPIWYRCKRPRHTSAITCFVLWVMSLLLGLLEGKACGL 177
Query 3703 ALDQAISMWALVISVTSNYSGVVTTIM----FLARAIVFVCVEYYPLLFITGNTLQCIML 3758
+ S W V +N VV + L + C + T+ +L
Sbjct 178 LFNSFDSYWCETFDVITNIWSVVFFGVLCGSSLTLLVRIFCGSQRIPMTRLYVTITLTVL 237
Query 3759 VYCFLGYCCCCYFGLFCLLNRYF 3781
V+ G Y+ L+ ++ ++
Sbjct 238 VFLIFGLPFGIYWILYQWISNFY 260
>sp|Q1RGZ3|ATP6_RICBR ATP synthase subunit a OS=Rickettsia bellii
(strain RML369-C) OX=336407 GN=atpB PE=3 SV=1
Length=242
Score = 38.5 bits (88), Expect = 1.5, Method: Composition-based stats.
Identities = 26/149 (17%), Positives = 52/149 (35%), Gaps = 11/149 (7%)
Query 3560 MLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAML-LVKHKHAFLCLF-- 3616
++ T +L F V + + F L I+ ++ VKH FL LF
Sbjct 87 VIFTLFVFILFCNLFGMIPYGFTVTSHIIITFALAILVFLMVTIVGFVKHGMHFLSLFLP 146
Query 3617 ------LLPSLATVAYFNMVYMPASWVMRIMTWLELADTS--LSGYRLKDCVMYASALVL 3668
L P + + F + PAS +R+ + + + ++Y L +
Sbjct 147 HGTPLWLAPLMIIIELFTYLARPASLSLRLAANMMAGHILLKVIASFVVTLMIYLKFLPI 206
Query 3669 LILMTARTVYDDAARRVWTLMNVITLVYK 3697
+++ A + +++ VY
Sbjct 207 PLMVILIGFEIFVAILQAYIFTILSCVYL 235
>sp|A8GUJ3|ATP6_RICB8 ATP synthase subunit a OS=Rickettsia bellii
(strain OSU 85-389) OX=391896 GN=atpB PE=3 SV=1
Length=242
Score = 38.5 bits (88), Expect = 1.5, Method: Composition-based stats.
Identities = 26/149 (17%), Positives = 52/149 (35%), Gaps = 11/149 (7%)
Query 3560 MLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAML-LVKHKHAFLCLF-- 3616
++ T +L F V + + F L I+ ++ VKH FL LF
Sbjct 87 VIFTLFVFILFCNLFGMIPYGFTVTSHIIITFALAILVFLMVTIVGFVKHGMHFLSLFLP 146
Query 3617 ------LLPSLATVAYFNMVYMPASWVMRIMTWLELADTS--LSGYRLKDCVMYASALVL 3668
L P + + F + PAS +R+ + + + ++Y L +
Sbjct 147 HGTPLWLAPLMIIIELFTYLARPASLSLRLAANMMAGHILLKVIASFVITLMIYLKFLPI 206
Query 3669 LILMTARTVYDDAARRVWTLMNVITLVYK 3697
+++ A + +++ VY
Sbjct 207 PLMVILIGFEIFVAILQAYIFTILSCVYL 235
>sp|P30738|RDRP_TMVKR Replicase large subunit OS=Tobacco mosaic
virus (strain Korean NC 82) OX=31746 PE=3 SV=2
Length=1616
Score = 39.7 bits (91), Expect = 1.7, Method: Composition-based stats.
Identities = 69/410 (17%), Positives = 124/410 (30%), Gaps = 81/410 (20%)
Query 5572 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5631
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFDED---LILVPGKQAAEMIRRRA------NSS 872
Query 5632 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM----ATNYDLSV 5687
I+ + V+ D F +N + DE M N+ +++
Sbjct 873 GIIVATKDNVKTVDSFMMNFGKST----------RCQFKRLFIDEGLMLHTGCVNFLVTM 922
Query 5688 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5747
+ VY GD Q+P + G P +F + + T RCPA
Sbjct 923 SLCEIAY---VY-GDTQQIPYINRV--SGFPYPAHFAKL-----EVDEVETRRTTLRCPA 971
Query 5748 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5807
++ ++ Y+ + + + G + S + + LT +
Sbjct 972 DVTHYLNRR-YEGFVMSTSSVKKSVSQEMVGGAAVINPISK------PLHGKILTFTQSD 1024
Query 5808 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---NVNRFNV 5864
++A+ Y+ TV QG Y V + T T S + V
Sbjct 1025 KEALLSRGYS------------DVHTVHEVQGETYSDVSLVRLTPTPVSIIAGDSPHVLV 1072
Query 5865 AITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQ 5924
A++R L++ ++ + E ++ D K+ G
Sbjct 1073 ALSRHTCS-------------LKYYTVVMDPLVSIIRDLEKLSSYLLDMYKVDAG----- 1114
Query 5925 APTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
L +D FK L V P IS M F + + G M
Sbjct 1115 TQXQLQIDSVFKGSNLFVATPKTGD-------ISDMQFYYDKCLPGNSTM 1157
>sp|B9JA28|ATP6_RHIR8 ATP synthase subunit a OS=Rhizobium rhizogenes
(strain K84 / ATCC BAA-868) OX=311403 GN=atpB PE=3 SV=1
Length=250
Score = 38.5 bits (88), Expect = 1.8, Method: Composition-based stats.
Identities = 26/163 (16%), Positives = 56/163 (34%), Gaps = 18/163 (11%)
Query 3553 VKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAML--LVKHKH 3610
KG + L+ L ++ +F+ + + + + +L +KH
Sbjct 79 TKGMKFFPLVFSLFMFVLTANLLGMVPYFYTVTSQIIVTFALALLVILTVILYGFIKHGF 138
Query 3611 AFLCLF--------LLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGY-------- 3654
FL LF LLP + + + + P S +R+ + +L +
Sbjct 139 GFLKLFVPQGVPGILLPLVVIIEIISFLSRPISLSVRLFANMLAGHITLKVFAGFVASLG 198
Query 3655 RLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYK 3697
L + + L L++ + + A + V+T +Y
Sbjct 199 TLGALGIGGAILPLIMTVALTGLEFLVAFLQAYVFAVLTCMYL 241
>sp|Q37376|NU2M_ACACA NADH-ubiquinone oxidoreductase chain 2 OS=Acanthamoeba
castellanii OX=5755 GN=ND2 PE=3 SV=1
Length=527
Score = 38.9 bits (89), Expect = 1.9, Method: Composition-based stats.
Identities = 22/128 (17%), Positives = 52/128 (41%), Gaps = 5/128 (4%)
Query 3562 LTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLC-LFLLPS 3620
+ ++LL + S +S+F ++ A +P LG + + +K+K ++ LF++ S
Sbjct 402 INLFSNLLEVNPSLSFSIFILLFSIAGIPPLLGFYSKFFLFLFSLKYKMYWMTILFVIFS 461
Query 3621 LATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDD 3680
+ +V Y+ + + + R W+ L D + + + L ++
Sbjct 462 VVSVFYY-IRLVKLMYFNRTTGWIFLYDIPFLNSLIISFITIINCLF---FFNPNLLFKL 517
Query 3681 AARRVWTL 3688
+ L
Sbjct 518 IYNFSFYL 525
>sp|P0DW67|RGYR2_SULAC Reverse gyrase 2 OS=Sulfolobus acidocaldarius
(strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157
/ NCIMB 11770) OX=330779 GN=rgy2 PE=2 SV=1
Length=1153
Score = 39.3 bits (90), Expect = 2.0, Method: Composition-based stats.
Identities = 25/144 (17%), Positives = 57/144 (40%), Gaps = 19/144 (13%)
Query 5546 HYVRITGLYPTLNISDEFSSNVANYQKV------GMQKY---STLQG-------PPGTGK 5589
Y + G + + + ++K+ +Q+Y ++G P G GK
Sbjct 50 KYSTLKGYSELYMDLEMYDDILRLFKKIVGGEPWSLQRYWLNKLVRGESFSLSAPTGVGK 109
Query 5590 SHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKV 5649
+ I ++Y + ++ + + D +CEK K + C++ P +V +
Sbjct 110 TTTLIVYSVYSHTTS-LFVVPTKSLRDQICEKLKKIGHLVSCNK--PEEDKVNVVTFHSI 166
Query 5650 NSTLEQYVFCTVNALPETTADIVV 5673
N ++++V L AD+++
Sbjct 167 NKNIDEFVRIKPKLLMVDDADMIL 190
>sp|Q5NQH8|RLME_ZYMMO Ribosomal RNA large subunit methyltransferase
E OS=Zymomonas mobilis subsp. mobilis (strain ATCC 31821
/ ZM4 / CP4) OX=264203 GN=rlmE PE=3 SV=1
Length=221
Score = 38.1 bits (87), Expect = 2.0, Method: Composition-based stats.
Identities = 38/153 (25%), Positives = 57/153 (37%), Gaps = 14/153 (9%)
Query 6850 DKGVAPG--TAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANK--------- 6898
D G+APG + V R+ P + V DL + T+ + T A K
Sbjct 66 DLGIAPGGWSQVARKKAPQAKI-VGIDLLEAAPIEGVTIFQNDFTDPEAQKKLIEALGGA 124
Query 6899 WDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNADLYKL 6958
DL++SDM H ++ F + L GGS K+ + DL L
Sbjct 125 ADLVLSDMAANTIGHAQTDHLRTMALVEEAAVFASETLREGGSFVAKVLAGGADKDLVAL 184
Query 6959 MGH-FSWW-TAFVTNVNASSSEAFLIGANYLGK 6989
+ F A SSE ++I N+ G+
Sbjct 185 LKRLFGQVKHAKPPASRRESSEWYVIAQNFRGE 217
>sp|Q67ES1|TR113_RAT Taste receptor type 2 member 113 OS=Rattus
norvegicus OX=10116 GN=Tas2r113 PE=3 SV=1
Length=309
Score = 38.5 bits (88), Expect = 2.1, Method: Composition-based stats.
Identities = 36/217 (17%), Positives = 72/217 (33%), Gaps = 31/217 (14%)
Query 2186 LCLDAGINYVKSPKFSKLFTIAMWLLLLSICLGSLICVTAAFGVLLSNFGAPSYCNGVRE 2245
+ L I++V+ K S + I L + I L L+ + VL +
Sbjct 27 IILMTCIDWVRRRKISLVDQILTALAITRITLILLVFIDWWVSVLFPALHET---GKILR 83
Query 2246 LYLNSSNVTTMDFCEGSFPCSICLSGLDSLDSYPALETIQVTISSYKLDLTILGLAAEWV 2305
+Y S T ++ C S+ + + S+ ++ L + V
Sbjct 84 MYFIS--WTVINHCNLWLTASLSIIYFLKIASFSSI------------IFLYLKFRVKNV 129
Query 2306 LAYMLFTKFFYLLGLSAIMQVFFGYFASHFISNSW-------------LMWFIISIVQMA 2352
+ L F+L +AI+ V+F N + F +
Sbjct 130 VFVTLLVSLFFLFINTAIVNVYFDVCFDGVQRNVSQVSRLYNHEQICKFLSFTNPMFAFI 189
Query 2353 PV-SAMVRMYIFFASFYYIWKSYVHIMDGCTSSTCMM 2388
P ++M ++ S + K+ H +GC + ++
Sbjct 190 PFVTSMATFFLLIFSLWRHLKNMKHNAEGCRDVSTIV 226
>sp|A1VC40|RLME_DESVV Ribosomal RNA large subunit methyltransferase
E OS=Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
OX=391774 GN=rlmE PE=3 SV=1
Length=204
Score = 37.7 bits (86), Expect = 2.1, Method: Composition-based stats.
Identities = 37/166 (22%), Positives = 59/166 (36%), Gaps = 11/166 (7%)
Query 6840 MRVIHFGA-------GSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCAT 6892
M+V+ GA G+ + V P VL L + ++ +
Sbjct 39 MKVLDLGAAPGSWSLGAAEKVGPRGRVLACDLQETDTVFPDNVTFMQENVFERSEAFENL 98
Query 6893 VHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQK-LALGGSIAVKITEHSW 6951
+ +D++ISDM PRT + ++ + + L GGS VKI
Sbjct 99 LDEIAPFDVVISDM-APRTTGTRFTDQARSLELCLEALAVADRCLIKGGSFVVKIFMGPD 157
Query 6952 NADLYKLM-GHFSWWTAFV-TNVNASSSEAFLIGANYLGKPKEQID 6995
+L + M FS +F + A S E F + Y G D
Sbjct 158 VQELVQAMRQRFSAVKSFKPKSSRAESKETFYVCLGYRGVETSDTD 203
>sp|Q729T9|RLME_DESVH Ribosomal RNA large subunit methyltransferase
E OS=Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644
/ NCIMB 8303 / VKM B-1760 / Hildenborough) OX=882 GN=rlmE
PE=3 SV=1
Length=204
Score = 37.7 bits (86), Expect = 2.1, Method: Composition-based stats.
Identities = 37/166 (22%), Positives = 59/166 (36%), Gaps = 11/166 (7%)
Query 6840 MRVIHFGA-------GSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCAT 6892
M+V+ GA G+ + V P VL L + ++ +
Sbjct 39 MKVLDLGAAPGSWSLGAAEKVGPRGRVLACDLQETDTVFPDNVTFMQENVFERSEAFENL 98
Query 6893 VHTANKWDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQK-LALGGSIAVKITEHSW 6951
+ +D++ISDM PRT + ++ + + L GGS VKI
Sbjct 99 LDEIAPFDVVISDM-APRTTGTRFTDQARSLELCLEALAVADRCLIKGGSFVVKIFMGPD 157
Query 6952 NADLYKLM-GHFSWWTAFV-TNVNASSSEAFLIGANYLGKPKEQID 6995
+L + M FS +F + A S E F + Y G D
Sbjct 158 VQELVQAMRQRFSAVKSFKPKSSRAESKETFYVCLGYRGVETSDTD 203
>sp|Q98745|RDRP_TMVRA Replicase large subunit OS=Tobacco mosaic
virus (strain Rakkyo) OX=138310 PE=3 SV=1
Length=1616
Score = 39.3 bits (90), Expect = 2.1, Method: Composition-based stats.
Identities = 67/406 (17%), Positives = 121/406 (30%), Gaps = 73/406 (18%)
Query 5572 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5631
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSNAKVVLVDGVPGCGKTKEILSRVNFDED---LILVPGKQAAEMIRRRA------NSS 872
Query 5632 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNAR 5691
I+ + V D F +N + DE M ++ + A
Sbjct 873 GIIVATKDNVRTVDSFMMN----------FGKTTRCQFKRLFIDEGLMLHTGCVNFLVAM 922
Query 5692 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5751
GD Q+P + G P +F+ + + T RCPA++
Sbjct 923 SLCDVAYVYGDTQQIPYINRV--SGFPYPAHFSKL-----EVDEVETRRTTLRCPADVTH 975
Query 5752 TVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5811
++ Y+ + + + G + S + + LT + ++A+
Sbjct 976 YLNRR-YEGFVVSTSSVKKSVSQEMVSGAAVINPISK------PLHGKILTFTQSDKEAL 1028
Query 5812 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---NVNRFNVAITR 5868
Y+ TV QG Y V + T T S + VA++R
Sbjct 1029 LSRGYS------------EVHTVHEVQGETYSDVSLVRLTPTPISIIAGDSPHVLVALSR 1076
Query 5869 AKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQAPTH 5928
L++ ++ + E ++ D K+ G+
Sbjct 1077 HTCS-------------LKYYTVVMDPLVSIIRDLEKLSSYLLDMYKVDAGIQ-----XQ 1118
Query 5929 LSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
L +D FK L V P IS M F + + G M
Sbjct 1119 LQIDSVFKGSNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTM 1157
>sp|Q66121|1A_CMVIX Replication protein 1a OS=Cucumber mosaic
virus (strain Ixora) OX=117114 GN=ORF1a PE=3 SV=1
Length=993
Score = 38.9 bits (89), Expect = 2.4, Method: Composition-based stats.
Identities = 58/300 (19%), Positives = 105/300 (35%), Gaps = 43/300 (14%)
Query 5578 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPA 5637
S + G G GK+ +++ PS +V TA +A D + C+ +
Sbjct 709 ISQVDGVAGCGKTTAI--KSIFEPSTDMVVTANKKSAQDVRMALFKSSDSKEACTFV--- 763
Query 5638 RARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHY 5697
T + + N P + V+ DE+ + L V ++L+A
Sbjct 764 -------------RTADSVLL---NECPTVSR--VLVDEVVLLHFGQLCAVMSKLKAVRA 805
Query 5698 VYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALV 5757
+ GD Q + + + + +++ D T R P ++V V +
Sbjct 806 ICFGDSEQ-------IAFSSRDASFDMRFSKIIPDETSDA--DTTFRSPQDVVPLVRLMA 856
Query 5758 YDNKLKA---HKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFIS 5814
K H + + K +T S++ + R ++T A + A IS
Sbjct 857 --TKALPRGTHSKYTKWVSQSKVKRSVTSRAISSVTLVDLDSSRFYITMTQADK-ASLIS 913
Query 5815 PYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN---VAITRAKI 5871
N + +TV SQG D+V + T +F+ VA+TR K+
Sbjct 914 RAKEMN-LPKTFWNERIKTVHESQGISEDHVTLVRLKSTKCDL-FKQFSYCLVALTRHKV 971
>sp|Q83943|1A_OLV2I Replication protein 1a OS=Olive latent virus
2 (isolate Italy) OX=650489 GN=ORF1a PE=3 SV=1
Length=908
Score = 38.9 bits (89), Expect = 2.4, Method: Composition-based stats.
Identities = 67/329 (20%), Positives = 115/329 (35%), Gaps = 56/329 (17%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5636
K + + G G GK++ + A + ++ TA + D + P C++
Sbjct 625 KKTWIDGVAGCGKTYEIVHTADIFKKDDLILTANKKSQEDIFSQ----LKPGTDCAK--- 677
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
R R T++ Y+ P+ A + DE + L
Sbjct 678 -RIR-----------TVDSYLLK-----PDVQAKRLFIDEAGLVHPGKLLAAMRFAECDD 720
Query 5697 YVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSAL 5756
+ GD Q+P + +L+P F L + T RCPA++ T++ L
Sbjct 721 CLLFGDSEQIPFVNIV---ESLQPAKF-----LKLEVDAREVRETTYRCPADVTATLATL 772
Query 5757 VYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWR-KAVFISP 5815
+K K K V + ++SA + LT A + + V ++
Sbjct 773 --------YKKKKIVTKSKVLKSVTSKSLASASAVSGLDPHSWHLTMYQADKAELVRVAR 824
Query 5816 YNSQNAVASKILGLPTQTVDSSQG------SEYDYVIFTQ-TTETAHSCNVNRFNVAITR 5868
N + V K +TV +QG Y + F Q + AH+ VAI+R
Sbjct 825 TNQMDDVWIKE---HIKTVHEAQGISVPHVKLYRFKTFDQPLFDAAHAEAYR--LVAISR 879
Query 5869 AKIGILCIMSDRDLYDK---LQFTSLEIP 5894
I ++ L L+F +IP
Sbjct 880 HTQSFTYIGVNQHLCKADRMLKFVICQIP 908
>sp|Q9TC94|YMF16_NEPOL Uncharacterized tatC-like protein ymf16
OS=Nephroselmis olivacea OX=31312 GN=YMF16 PE=3 SV=1
Length=247
Score = 38.1 bits (87), Expect = 2.4, Method: Composition-based stats.
Identities = 32/228 (14%), Positives = 74/228 (32%), Gaps = 12/228 (5%)
Query 3553 VKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAF 3612
+K ++ TFL +I ++ +FF+V+ L G + M H + F
Sbjct 12 IKYRFLYIFFTFLLCFIICTIYSESIMFFYVHPLINLTSMQG-KHLIFTEMSEAFHTYIF 70
Query 3613 LCLFLLPSLATVAYFNMVYM----PASWVMRIMTWLELADTSLSGYRLKDCVMYASAL-- 3666
LC F T YF + P+++ + L+ + ++Y L
Sbjct 71 LC-FFTSIYCTFPYFFYQFWAFFIPSTYQFERLQLRFLSFFFFTLLFFSCIIIYFIILPE 129
Query 3667 ----VLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYS 3722
L + R+ + + ++ ++ + ++L +++ +
Sbjct 130 IWSFFLHFEKKSYYFNLQLEARISSYIQFTFQIFSYFFVLFQCPLFTHFSLNLNLLTISF 189
Query 3723 GVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCY 3770
V + ++ P + I+ +Y + C Y
Sbjct 190 LVNSRKYIYFLFLILAAFLSPPDILSQFFLFSLIVFMYELCVFYSCFY 237
>sp|P04540|NU5M_TRYBB NADH-ubiquinone oxidoreductase chain 5 OS=Trypanosoma
brucei brucei OX=5702 GN=ND5 PE=3 SV=1
Length=590
Score = 38.5 bits (88), Expect = 2.5, Method: Composition-based stats.
Identities = 18/125 (14%), Positives = 45/125 (36%), Gaps = 6/125 (5%)
Query 3024 VVAGGIIAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTILCLVPAYSFLPGVYS 3083
+V I + + ++ + F +F ++ V + L +F + + + L +
Sbjct 456 LVYCLISLYMCILSIFFIIDFVCIFVFSSYCVFWSFFLNFYNFFDIAIFVVFLILSVGF- 514
Query 3084 VFYLYLTFYFTNDVSFLAHLQ--WFAMFSPIVPFWITAIYVFCISLKHCH--WFFNNYLR 3139
Y F++ ++ + +F + +V Y C+ + W F Y R
Sbjct 515 -LYYGCLFFYFFNIDCIMLFWRIFFVIIILVVFMIFCCWYFVCMIIFMLLFVWNFVIYFR 573
Query 3140 KRVMF 3144
+ +
Sbjct 574 YNLKY 578
Score = 37.3 bits (85), Expect = 6.2, Method: Composition-based stats.
Identities = 27/202 (13%), Positives = 68/202 (34%), Gaps = 25/202 (12%)
Query 3582 FVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIM 3641
F++ FL F L ++ I + ++ FL+ S+ Y+ + +
Sbjct 19 FMFGRNFLSFWLSLVMIIFIVLCMI-------FSFLMVSVCLYGYYYYDFCLILMLDFCF 71
Query 3642 TWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDD-------AARRVWTLM-NVIT 3693
WL SG+ + ++ ++ +Y D ++ + N+
Sbjct 72 IWLTYV---CSGFYMFIMLLINMVFCFIVFYAFYYMYFDMLLGRFLIIFWIFVVCMNLFI 128
Query 3694 LVYKVYYGNALDQAISMWALVISVTSNYSGVV----TTIMFLARAIVFVCVEYYPLLFIT 3749
L Y + + +++ + Y F+ + + + + ++F++
Sbjct 129 LSYDFLTAYCGWELLGLFSFFLISYFWYRFFALKFGFKAFFIGKIGDVLLIFAFSIIFLS 188
Query 3750 GNTLQCIMLVYCFLGYCCCCYF 3771
M + FL + C Y+
Sbjct 189 NGF---CMTTFYFLNFFCMDYY 207
>sp|O93058|RDRP_TMVOM Replicase large subunit OS=Tobacco mosaic
virus (strain OM) OX=12251 PE=3 SV=1
Length=1616
Score = 38.9 bits (89), Expect = 2.6, Method: Composition-based stats.
Identities = 69/410 (17%), Positives = 124/410 (30%), Gaps = 81/410 (20%)
Query 5572 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5631
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFDED---LILVPGKQAAEMIRRRA------NSS 872
Query 5632 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM----ATNYDLSV 5687
I+ + V+ D F +N + DE M N+ +++
Sbjct 873 GIIVATKDNVKTVDSFMMNFGKST----------RCQFKRLFIDEGLMLHTGCVNFLVAM 922
Query 5688 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5747
+ VY GD Q+P + G P +F + + T RCPA
Sbjct 923 SLCEIAY---VY-GDTQQIPYINRV--SGFPYPAHFAKL-----EVDEVETRRTTLRCPA 971
Query 5748 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5807
++ ++ Y+ + + + G + S + + LT +
Sbjct 972 DVTHYLNRR-YEGFVMSTSSVKKSVSQEMVGGAAVINPISK------PLHGKILTFTQSD 1024
Query 5808 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---NVNRFNV 5864
++A+ Y+ TV QG Y V + T T S + V
Sbjct 1025 KEALLSRGYS------------DVHTVHEVQGETYSDVSLVRLTPTPVSIIAGDSPHVLV 1072
Query 5865 AITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQ 5924
A++R L++ ++ + E ++ D K+ G
Sbjct 1073 ALSRHTCS-------------LKYYTVVMDPLVSIIRDLEKLSSYLLDMYKVDAG----- 1114
Query 5925 APTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
L +D FK L V P IS M F + + G M
Sbjct 1115 TQXQLQIDSVFKGSNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTM 1157
>sp|P26848|NU4M_MARPO NADH-ubiquinone oxidoreductase chain 4 OS=Marchantia
polymorpha OX=3197 GN=ND4 PE=3 SV=2
Length=495
Score = 38.5 bits (88), Expect = 2.6, Method: Composition-based stats.
Identities = 32/204 (16%), Positives = 75/204 (37%), Gaps = 16/204 (8%)
Query 3548 KFKKIVKGTHHWM-LLTFLTSLLILVQSTQWSLFF-FVYENAFLPFTLG--IMAIAACAM 3603
++++G W L+TFL SL ++ + F FV +LP++ + I ++
Sbjct 32 SRVRLIRGITIWTSLITFLYSLFFWIRFENDTAKFQFVETIRWLPYSNINFYIGIDGISL 91
Query 3604 LLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYA 3663
V L FL P V ++++ +++ L ++
Sbjct 92 FFV-----ILTTFLTPICILVGFYSVKSYKKEYMIAFFICESFLIAVFCSLDLLIFYVFF 146
Query 3664 SALVLLILMTA-------RTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVIS 3716
++++ + + R + ++TLM + ++ + + + L+ +
Sbjct 147 ESVLIPMFIIIGVWGSRQRKIKAAYQFFLYTLMGSLFMLLAILFIFFQTGTTDLQILLTT 206
Query 3717 VTSNYSGVVTTIMFLARAIVFVCV 3740
S ++ I F A V V +
Sbjct 207 EFSERRQILLWIAFFASFSVKVPM 230
>sp|P90211|RDRP_TMOB Replicase large subunit OS=Tobamovirus Ob
OX=31749 PE=3 SV=1
Length=1616
Score = 38.9 bits (89), Expect = 2.6, Method: Composition-based stats.
Identities = 44/302 (15%), Positives = 78/302 (26%), Gaps = 48/302 (16%)
Query 5573 VGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCS 5632
V K + + G PG GK+ + + + A A+ ++
Sbjct 822 VSSAKVTLVDGVPGCGKTKEILRRVNFSED---LVLVPGKEAA------AMIRKRANQSG 872
Query 5633 RIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARL 5692
I+ V+ D F + P + DE M + +
Sbjct 873 NIVANNDNVKTVDSF----------LMNLGKGPVCQFKRLFVDEGLMLHPGCVYFLVKLS 922
Query 5693 RAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5752
GD Q+P + +L+ T RCP ++
Sbjct 923 LCNEAFVFGDTQQIPYIN-----RVQNFPFPQHFSKLIVDETEKR--RTTLRCPVDVTHF 975
Query 5753 VSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVF 5812
++ YD + G +A+ P ++ + K
Sbjct 976 LN-QCYDGAVTTTSKTQRSVGLEVVGG-------AAVMNPVTKPLKGKIVTFTQSDKLTM 1027
Query 5813 ISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNR---FNVAITRA 5869
+S + TV QG Y+ V + T T V +TR
Sbjct 1028 LS----RGYQ-------DVNTVHEIQGETYEEVSLVRLTPTPIHIISRESPHVLVGLTRH 1076
Query 5870 KI 5871
Sbjct 1077 TR 1078
>sp|P03586|RDRP_TMV Replicase large subunit OS=Tobacco mosaic
virus (strain vulgare) OX=12243 PE=1 SV=2
Length=1616
Score = 38.9 bits (89), Expect = 2.6, Method: Composition-based stats.
Identities = 69/410 (17%), Positives = 124/410 (30%), Gaps = 81/410 (20%)
Query 5572 KVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKC 5631
V K + G PG GK+ + + + A + + +A +
Sbjct 822 HVSSAKVVLVDGVPGCGKTKEILSRVNFDED---LILVPGKQAAEMIRRRA------NSS 872
Query 5632 SRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISM----ATNYDLSV 5687
I+ + V+ D F +N + DE M N+ +++
Sbjct 873 GIIVATKDNVKTVDSFMMNFGKST----------RCQFKRLFIDEGLMLHTGCVNFLVAM 922
Query 5688 VNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPA 5747
+ VY GD Q+P + G P +F + + T RCPA
Sbjct 923 SLCEIAY---VY-GDTQQIPYINRV--SGFPYPAHFAKL-----EVDEVETRRTTLRCPA 971
Query 5748 EIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAW 5807
++ ++ Y+ + + + G + S + + LT +
Sbjct 972 DVTHYLNRR-YEGFVMSTSSVKKSVSQEMVGGAAVINPISK------PLHGKILTFTQSD 1024
Query 5808 RKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSC---NVNRFNV 5864
++A+ Y+ TV QG Y V + T T S + V
Sbjct 1025 KEALLSRGYS------------DVHTVHEVQGETYSDVSLVRLTPTPVSIIAGDSPHVLV 1072
Query 5865 AITRAKIGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKIITGLHPTQ 5924
A++R L++ ++ + E ++ D K+ G
Sbjct 1073 ALSRHTCS-------------LKYYTVVMDPLVSIIRDLEKLSSYLLDMYKVDAG----- 1114
Query 5925 APTHLSVDIKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNM 5974
L +D FK L V P IS M F + + G M
Sbjct 1115 TQXQLQIDSVFKGSNLFVAAPKTGD-------ISDMQFYYDKCLPGNSTM 1157
>sp|P03588|1A_BMV Replication protein 1a OS=Brome mosaic virus
OX=12302 GN=ORF1a PE=1 SV=1
Length=961
Score = 38.9 bits (89), Expect = 2.6, Method: Composition-based stats.
Identities = 52/314 (17%), Positives = 93/314 (30%), Gaps = 68/314 (22%)
Query 5577 KYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIP 5636
S + G G GK+ + ++ TA +A D ++
Sbjct 679 DISMVDGVAGCGKTTAI--KDAFRMGEDLIVTANRKSAEDVRMALFPDTYNSKVALDVV- 735
Query 5637 ARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKH 5696
T + + + +P ++ DE + L VV A +
Sbjct 736 --------------RTADSAIM---HGVPSCHR--LLVDEAGLLHYGQLLVVAALSKCSQ 776
Query 5697 YVYIGDPAQLPAPR----TLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDT 5752
+ GD Q+ L G L+ + + V RCP +++
Sbjct 777 VLAFGDTEQISFKSRDAGFKLLHGNLQYDRRDVV-------------HKTYRCPQDVIAA 823
Query 5753 VSAL---------VYDNKLKAHKDKSAQCFKMFYKG-VITHDVSSAINRPQIGVVREFLT 5802
V+ L Y + K + + G +T D + LT
Sbjct 824 VNLLKRKCGNRDTKYQSWTSESKVSRSLTKRRITSGLQVTIDPNRTY-----------LT 872
Query 5803 RNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRF 5862
A + A + V+ + +TV +QG D V + T C++ +
Sbjct 873 MTQADKAA--LQTRAKDFPVSKDWIDGHIKTVHEAQGISVDNVTLVRLKSTK--CDLFKH 928
Query 5863 N----VAITRAKIG 5872
VA+TR K
Sbjct 929 EEYCLVALTRHKKS 942
>sp|C3MGQ4|RLME_SINFN Ribosomal RNA large subunit methyltransferase
E OS=Sinorhizobium fredii (strain NBRC 101917 / NGR234)
OX=394 GN=rlmE PE=3 SV=1
Length=245
Score = 37.7 bits (86), Expect = 2.7, Method: Composition-based stats.
Identities = 25/95 (26%), Positives = 35/95 (37%), Gaps = 2/95 (2%)
Query 6899 WDLIISDMYDPRTKHVTKENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSWNAD-LYK 6957
DL++SDM P T H ++ F LA GG K + D L
Sbjct 138 PDLVLSDMAAPTTGHRQTDHLRTMHLCEVAAHFAVDVLAKGGHFLAKTFQGGTERDLLNM 197
Query 6958 LMGHFSWW-TAFVTNVNASSSEAFLIGANYLGKPK 6991
L +FS + S E FL+ + G+ K
Sbjct 198 LKQNFSQVIHVKPASSRTESVEMFLLAKGFKGRRK 232
>sp|Q9WAL8|POL1_SDVS5 RNA1 polyprotein OS=Satsuma dwarf virus
(isolate Satsuma mandarin/Japan/S-58/1977) OX=650481 PE=3 SV=1
Length=2081
Score = 38.9 bits (89), Expect = 2.8, Method: Composition-based stats.
Identities = 36/204 (18%), Positives = 60/204 (29%), Gaps = 34/204 (17%)
Query 4948 IAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGWDYPKCDRAMPNMLRIMASLVL 5007
+ A +G + + W +L DY D + P R++ ++
Sbjct 1649 MVAHDELPSKVGINVYSESWDRLLGRHTRLANHFT---GDYSGFDTSTP---RVLVYAII 1702
Query 5008 ARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQ 5067
+ + + N VL+ ++ G LY GGT SG A T NSV N
Sbjct 1703 DKINELADDGEVNQRTRRNIIRFVLNRYLISDGVLYEIHGGTPSGFAPTVMINSVVNEFY 1762
Query 5068 AVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDHEFVDEFYAYLRKHFSMMIL 5127
+ ++ L+ Y Y
Sbjct 1763 ----------------LKWSWIGLLKEAGYANQATLYAFHEATEISLYG----------- 1795
Query 5128 SDDAVVCYNSNYAAQGLVASIKNF 5151
DD V + A+ + +I NF
Sbjct 1796 -DDNFVSVATPVASVYNLTTISNF 1818
>sp|Q8QL26|Y1070_SIRV1 Uncharacterized protein 1070 OS=Sulfolobus
islandicus rod-shaped virus 1 OX=157898 GN=1070 PE=4 SV=1
Length=1070
Score = 38.5 bits (88), Expect = 2.9, Method: Composition-based stats.
Identities = 41/272 (15%), Positives = 79/272 (29%), Gaps = 17/272 (6%)
Query 548 FARTLDAANHSIPDLQRAAVTILDGISEQSLRLVDAMVYTSDLLTNSVIIMAYVTGGLVQ 607
I +L+ I +V+ + + L ++ + +
Sbjct 19 LGELGTFFADEIENLENFTNWISSDFINFINAIVNDIKNIASFLGQAISDIPTFMVNIAT 78
Query 608 QTSQWLSNLLGTTVEKLRPIFEWIEAKLSAGVEFLKDAWEILKFLITGVFDIVKGQIQVA 667
L N + T + ++ W E ++ EFL I I + + V
Sbjct 79 NFLTILQNFVQTAISTIQGFVSWFEQQIVGAFEFLSS---IASDFINSAYSFFQNVANVF 135
Query 668 SDNIKDCVKCFIDVVNKALEMCIDQVTIAGAKLRSLNLGEVFIAQ-SKGLYRQCIRGKEQ 726
+ I + F++ ++ ++ A ++L FIA + G + I K
Sbjct 136 AQIISGVISDFLNFFGANMK----HISNAISQLSQFLS--PFIAPITIGKFLPVIVDKLA 189
Query 727 LQL------LMPLKAPKEVTFLEGDSHDTVLTSEEVVLKNGELEALETPVDSFTNGAIVG 780
L L P+ ++ G+ V N L T + F +
Sbjct 190 EILPEIEIDLAPVGLGGKIPIKFGEIIKA-FAETSVDFLNEIRTELATTLKEFIKEPFIS 248
Query 781 TPVCVNGLMLLEIKDKEQYCALSPGLLATNNV 812
+ EI + A P L V
Sbjct 249 DFKISAREIFNEIGLGDLPFADPPFQLIGRWV 280
>sp|Q1RH22|Y1261_RICBR Uncharacterized lipoprotein RBE_1261 OS=Rickettsia
bellii (strain RML369-C) OX=336407 GN=RBE_1261 PE=3
SV=1
Length=1157
Score = 38.5 bits (88), Expect = 3.0, Method: Composition-based stats.
Identities = 28/178 (16%), Positives = 56/178 (31%), Gaps = 30/178 (17%)
Query 2992 SGVFCGVDAMNLIANIFTPLVQPVGALDVSASVVAGGIIAILVTCAAYYFMKFRRVFGEY 3051
G V A+ + +FT +G ++++ + I+ + V K F +Y
Sbjct 288 PGYRLSVSALLTLYIMFTGFSFLIGNINMTHVELVVRILKVSVVSILLSTSKAWTFFHDY 347
Query 3052 NHVVAANALLFLMS------------------------FTILCLVPAYSFLPGVYSV-FY 3086
V L ++ F++L + P +Y + Y
Sbjct 348 LFVFFVEGLAQILQIVQDASTGQSLLSLLISPQTLSKLFSLLFVDPLGFIYIILYLIALY 407
Query 3087 LYLTFYFTNDVSFLAHLQWFAMFSPIVPFWITAIYVFCISLKHCHWFFNNYLRKRVMF 3144
F + +L L M + P +I + F N+LR+ + +
Sbjct 408 FIFLLIFKATIIYLTALITIGMIITMAPIFIC-----FMLFNITRSLFENWLRQLISY 460
>sp|Q04574|POL1_BAYMG Genome polyprotein 1 OS=Barley yellow mosaic
virus (isolate Germany) OX=31728 PE=3 SV=1
Length=2412
Score = 38.5 bits (88), Expect = 3.1, Method: Composition-based stats.
Identities = 67/395 (17%), Positives = 133/395 (34%), Gaps = 56/395 (14%)
Query 4785 NKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPT---MCDIRQLLFV 4841
N D YDF F ++ +A D +YN + +L
Sbjct 1651 NDDVYDFMREHPTFTWLKDFMNEYAPSVLSYSAYYKDLC--KYNRAKHVLTYNPEELHCA 1708
Query 4842 VEVVDKYFD--CYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAY 4899
+ + K + G + Q +V+++ + + GK R +S ++ L
Sbjct 1709 TKGLIKMLEDAGLTQGSVRTPQQVVSDIQWNTSAGPSYQGKKRDLCAHLSDDEVLHLAEV 1768
Query 4900 TKRNVIPTITQMNLKYAISAKNRARTVAGVS------ICSTMTNRQFHQKLL------KS 4947
++ + + + S K RT+ V ++ F K K
Sbjct 1769 CRQQFLEGKSTGV--WNGSLKAELRTIEKVEAEKTRVFTASPITSLFAMKFYVDDFNKKF 1826
Query 4948 IAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLMGW-----DYPKCDRAM-PNMLRI 5001
A A +G +KF GW ++ + P GW D + D ++ P +
Sbjct 1827 YATNLKAPHTVGINKFGRGWEK----LHDKLNRP---GWLHGSGDGSRFDSSIDPFFFDV 1879
Query 5002 MASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANS 5061
+ ++ RKH + +E + + + G + K G +SG +T N+
Sbjct 1880 VKTI---RKHFLPSEHHKAIDLIYDEILN--TTICLANGMVIRKNVGNNSGQPSTVVDNT 1934
Query 5062 VFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRD---VDHEFVDEF---Y 5115
+ + A L +K D+ + L R + + + +F +EF +
Sbjct 1935 L--------VLMTAFLYAYIHKTGDRELALLNERFIFVCNGDDNKFAISPQFDEEFGHDF 1986
Query 5116 AYLRKHFSMMILSDD--AVVCYNSNYAAQGLVASI 5148
+ + DD + +C N Y + +V +
Sbjct 1987 SPELVELGLTYEFDDITSDICEN-PYMSLTMVKTP 2020
>sp|Q9BUN8|DERL1_HUMAN Derlin-1 OS=Homo sapiens OX=9606 GN=DERL1
PE=1 SV=1
Length=251
Score = 37.7 bits (86), Expect = 3.3, Method: Composition-based stats.
Identities = 35/183 (19%), Positives = 69/183 (38%), Gaps = 12/183 (7%)
Query 3621 LATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTART---- 3676
L + AY + P +++ R W + T +Y L L + R
Sbjct 33 LISPAY--LFLWPEAFLYRFQIWRPITATFYFPVGPGTGFLYLVNLYFLYQYSTRLETGA 90
Query 3677 VYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIV 3736
A ++ L + + V G A+D + M L++SV ++ + ++
Sbjct 91 FDGRPADYLFML--LFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDMIVSFWFGT 148
Query 3737 FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQE 3796
Y P + + N + ++ +G + F L+ RY + LG ++ +ST +
Sbjct 149 RFKACYLPWVILGFNYIIGGSVINELIGNLVGHLY--FFLMFRY-PMDLGGRNF-LSTPQ 204
Query 3797 FRY 3799
F Y
Sbjct 205 FLY 207
>sp|Q71SS4|DERL1_BOVIN Derlin-1 OS=Bos taurus OX=9913 GN=DERL1
PE=2 SV=1
Length=251
Score = 37.3 bits (85), Expect = 3.4, Method: Composition-based stats.
Identities = 36/183 (20%), Positives = 69/183 (38%), Gaps = 12/183 (7%)
Query 3621 LATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTART---- 3676
L + AYF P +++ R W + T +Y L L + R
Sbjct 33 LISPAYF--FLWPEAFLYRFQIWRPITATFYFPVGPGTGFLYLVNLYFLYQYSTRLETGA 90
Query 3677 VYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIV 3736
A ++ L + + V G A+D + M L++SV ++ + ++
Sbjct 91 FDGRPADYLFML--LFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDMIVSFWFGT 148
Query 3737 FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQE 3796
Y P + + N + ++ +G + F L+ RY + LG ++ +ST +
Sbjct 149 RFKACYLPWVILGFNYIIGGSVINELIGNLVGHLY--FFLMFRY-PMDLGGRNF-LSTPQ 204
Query 3797 FRY 3799
F Y
Sbjct 205 FLY 207
>sp|Q5R9W3|DERL1_PONAB Derlin-1 OS=Pongo abelii OX=9601 GN=DERL1
PE=2 SV=1
Length=251
Score = 37.3 bits (85), Expect = 3.5, Method: Composition-based stats.
Identities = 35/183 (19%), Positives = 69/183 (38%), Gaps = 12/183 (7%)
Query 3621 LATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTART---- 3676
L + AY + P +++ R W + T +Y L L + R
Sbjct 33 LISPAY--LFLWPEAFLYRFQIWRPITATFYFPVGPGTGFLYLVNLYFLYHYSTRLETGA 90
Query 3677 VYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIV 3736
A ++ L + + V G A+D + M L++SV ++ + ++
Sbjct 91 FDGRPADYLFML--LFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDMIVSFWFGT 148
Query 3737 FVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLVSTQE 3796
Y P + + N + ++ +G + F L+ RY + LG ++ +ST +
Sbjct 149 RFKACYLPWVILGFNYIIGGSVINELIGNLVGHLY--FFLMFRY-PMDLGGRNF-LSTPQ 204
Query 3797 FRY 3799
F Y
Sbjct 205 FLY 207
>sp|Q51151|LCBA_NEIMI Capsular polysaccharide phosphotransferase
OS=Neisseria meningitidis serogroup B OX=491 PE=3 SV=1
Length=373
Score = 37.7 bits (86), Expect = 3.6, Method: Composition-based stats.
Identities = 34/197 (17%), Positives = 66/197 (34%), Gaps = 15/197 (8%)
Query 841 RITFELDERVDKVLNEKCSVYTVESGT-EVTEFACVVAEAVVKTLQPVSDLLTNMGIDLD 899
+ E LN++ Y VE E EF + A+A + +L ++L N ID+
Sbjct 8 KFFRESHIFFRDFLNKRFPPYNVEQPIPETEEFTLINADANLASLTE--NVLPNFPIDV- 64
Query 900 EWSVATFYLFDDAGEENFSSRMYCSFYPPDEEEEDDAECEEEEIDETCEHEYGTEDDYQG 959
+ + D ++ + + Y + P D+E+ + E Y + +
Sbjct 65 ------VFTWVDNTDKAWQEQYYRTLQPIDQEDIGLYATDPARFSNHNELFYSVQAVQKF 118
Query 960 LPLEFGASAETVRVEEEEEEDWLDDTTEQSEIEPEPEPTPEEPVNQFTGYLKLTDNVAIK 1019
+P V +++ WLD+ + + N+ K
Sbjct 119 MPW----VRNIFIVTADQKPKWLDENIHSKIKLINHSQLIDAKYLPTFNSHVIEANLY-K 173
Query 1020 CVDIVKEAQSANPMVIV 1036
D+ + N V V
Sbjct 174 IPDLSEHFIYFNDDVFV 190
>sp|Q971T7|RGYR1_SULTO Reverse gyrase 1 OS=Sulfurisphaera tokodaii
(strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) OX=273063
GN=rgy1 PE=1 SV=1
Length=1156
Score = 38.5 bits (88), Expect = 3.7, Method: Composition-based stats.
Identities = 19/129 (15%), Positives = 54/129 (42%), Gaps = 3/129 (2%)
Query 5545 EHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSAR 5604
E + I ++ + ++ ++ +++ + +L P G GK+ + +L++ S
Sbjct 65 ETFEEIVRIFKRVIGNEPWNLQKYWIKRLAKSESFSLSAPTGLGKTTTLLVYSLFF-SNT 123
Query 5605 IVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNAL 5664
+Y +++ D +CE+ C+ + V F+ ++ + YV +
Sbjct 124 TLYVVPTNSLKDQICERLRNMGAKVSCNDVKEEYINVATFN--RILRHYDNYVSLQPKLV 181
Query 5665 PETTADIVV 5673
+D+++
Sbjct 182 IVDDSDMIL 190
>sp|Q92JP0|ATP6_RICCN ATP synthase subunit a OS=Rickettsia conorii
(strain ATCC VR-613 / Malish 7) OX=272944 GN=atpB PE=3
SV=1
Length=242
Score = 37.3 bits (85), Expect = 3.7, Method: Composition-based stats.
Identities = 34/176 (19%), Positives = 64/176 (36%), Gaps = 22/176 (13%)
Query 3534 FDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTL 3593
D++ Q GV + KF +V ++L L + F + + FTL
Sbjct 70 ADMLNQNIGVKGR-KFIPLVFSLFIFILFCNLLGMT--------PYSFTTTSHIIVTFTL 120
Query 3594 GIMAIAACAML-LVKHKHAFLCLF--------LLPSLATVAYFNMVYMPASWVMRIMTWL 3644
I+ ++ VKH FL LF L P + + F + P S +R+ +
Sbjct 121 AILVFLMVTIVGFVKHGLRFLTLFLPHGTPLWLAPLMIVIELFTYLARPVSLSLRLAANM 180
Query 3645 ELADTSLS---GYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYK 3697
L G+ + ++Y L + I++ A + +++ +Y
Sbjct 181 MAGHVLLKVIAGFTVS-LMIYLKFLPIPIMVILIGFEIFVAILQAYIFTILSCMYL 235
>sp|C3PM51|ATP6_RICAE ATP synthase subunit a OS=Rickettsia africae
(strain ESF-5) OX=347255 GN=atpB PE=3 SV=1
Length=242
Score = 37.3 bits (85), Expect = 3.9, Method: Composition-based stats.
Identities = 33/176 (19%), Positives = 64/176 (36%), Gaps = 22/176 (13%)
Query 3534 FDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTL 3593
D++ Q GV + KF ++ ++L L + F + + FTL
Sbjct 70 ADMLNQNIGVKGR-KFIPLIFSLFIFILFCNLLGMT--------PYSFTTTSHIIVTFTL 120
Query 3594 GIMAIAACAML-LVKHKHAFLCLF--------LLPSLATVAYFNMVYMPASWVMRIMTWL 3644
I+ ++ VKH FL LF L P + + F + P S +R+ +
Sbjct 121 AILVFLMVTIVGFVKHGLRFLTLFLPHGTPLWLAPLMIVIELFTYLARPVSLSLRLAANM 180
Query 3645 ELADTSLS---GYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYK 3697
L G+ + ++Y L + I++ A + +++ +Y
Sbjct 181 MAGHVLLKVIAGFTVS-LMIYLKFLPIPIMVILIGFEIFVAILQAYIFTILSCMYL 235
>sp|P29152|POLG_PSBMV Genome polyprotein OS=Pea seed-borne mosaic
virus (strain DPD1) OX=31736 PE=1 SV=1
Length=3206
Score = 38.1 bits (87), Expect = 4.1, Method: Composition-based stats.
Identities = 35/159 (22%), Positives = 58/159 (36%), Gaps = 20/159 (13%)
Query 4925 TVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVETPHLM 4984
T+ G +C N F+ L+ +G +KFY GW+ L + P
Sbjct 2591 TLLGGKVCVDDFNNFFYSCHLR-------GPWTVGITKFYAGWNEFLSKL------PD-- 2635
Query 4985 GWDYPKCD--RAMPNMLRIMASLVLARKHNTCCNLSHRFYRLANECAQVLSEMVMC-GGS 5041
GW Y D R ++ + + VL + L N +++ + GS
Sbjct 2636 GWLYCDADGSRFDSSLTPYLINAVLELRLRFMEEWDAGEQMLKNLYTEIIYTPIATPDGS 2695
Query 5042 LYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTD 5080
+ K G +SG +T N++ I + LL D
Sbjct 2696 VIKKTKGNNSGQPSTVVDNTLMVILAMQYS--LQLLGVD 2732
>sp|Q9LJJ5|AATPB_ARATH AAA-ATPase At3g28610 OS=Arabidopsis thaliana
OX=3702 GN=At3g28610 PE=2 SV=1
Length=474
Score = 37.7 bits (86), Expect = 4.1, Method: Composition-based stats.
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 2/43 (5%)
Query 5557 LNISDEFSSNVANYQKVGM--QKYSTLQGPPGTGKSHFAIGLA 5597
LN F++ Y+K+G ++ L GPPGTGKS +A
Sbjct 216 LNDLAAFNNGKDYYKKIGKAWKRGYLLYGPPGTGKSTMIAAMA 258
>sp|Q09887|YC9D_SCHPO Uncharacterized amino-acid permease C584.13
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812
GN=SPCC584.13 PE=3 SV=1
Length=544
Score = 38.1 bits (87), Expect = 4.1, Method: Composition-based stats.
Identities = 36/194 (19%), Positives = 71/194 (37%), Gaps = 11/194 (6%)
Query 3547 GKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLV 3606
G ++ + W S+L L+ S +++ + A P + IA + V
Sbjct 32 GYKQEFKREFSAWTSFCVSFSVLGLLPSFASTMY-YTTGYAGTPAMVWGWLIAMVFVQCV 90
Query 3607 KHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASAL 3666
+ A LC +P+ + Y V P W WL L V Y+ A
Sbjct 91 ANGMAELCS-SMPTSGGLYYAAAVLAPKGW-GPFAAWLTGWSNYLVQVTGPPSVAYSFAG 148
Query 3667 VLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVT 3726
++L L+ + L+ V ++ + + + + ++++ N G V
Sbjct 149 MILTLVQLHNPNFETQNYQIFLLAVAAMIAQGFISSMPTKVLAVF--------NTWGTVL 200
Query 3727 TIMFLARAIVFVCV 3740
++FLA ++ V
Sbjct 201 NMLFLAIVMITVLA 214
>sp|A8F0C9|ATP6_RICM5 ATP synthase subunit a OS=Rickettsia massiliae
(strain Mtu5) OX=416276 GN=atpB PE=3 SV=2
Length=242
Score = 37.3 bits (85), Expect = 4.2, Method: Composition-based stats.
Identities = 34/176 (19%), Positives = 64/176 (36%), Gaps = 22/176 (13%)
Query 3534 FDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTL 3593
D++ Q GV + KF +V ++L L + F + + FTL
Sbjct 70 ADMLNQNIGVKGR-KFIPLVFSLFIFILFCNLLGMT--------PYSFTTTSHIIVTFTL 120
Query 3594 GIMAIAACAML-LVKHKHAFLCLF--------LLPSLATVAYFNMVYMPASWVMRIMTWL 3644
I+ ++ VKH FL LF L P + + F + P S +R+ +
Sbjct 121 AILVFLTVTIVGFVKHGLRFLTLFLPHGTPLWLAPLMIVIELFTYLARPVSLSLRLAANM 180
Query 3645 ELADTSLS---GYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYK 3697
L G+ + ++Y L + ++M A + +++ +Y
Sbjct 181 MAGHVLLKVIAGFTVS-LMIYLKFLPIPLMMILIGFEIFVAILQAYIFTILSCMYL 235
>sp|Q99J56|DERL1_MOUSE Derlin-1 OS=Mus musculus OX=10090 GN=Derl1
PE=1 SV=1
Length=251
Score = 37.0 bits (84), Expect = 4.6, Method: Composition-based stats.
Identities = 34/187 (18%), Positives = 68/187 (36%), Gaps = 10/187 (5%)
Query 3617 LLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTART 3676
L+ L ++ P +++ R W T +Y L L + R
Sbjct 27 LIGKLGIISPAYFFLWPEAFLYRFQIWRPFTATFYFPVGPGTGFLYLVNLYFLYQYSTRL 86
Query 3677 ----VYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSNYSGVVTTIMFLA 3732
A ++ L + + V G A+D + M L++SV ++ + ++
Sbjct 87 EAGAFDGRPADYLFML--LFNWICIVITGLAMDMQLLMIPLIMSVLYVWAQLNRDLIVSF 144
Query 3733 RAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYDYLV 3792
Y P + + N + ++ +G + F L+ RY + LG ++ +
Sbjct 145 WFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLY--FFLMFRY-PMDLGGRNF-L 200
Query 3793 STQEFRY 3799
ST +F Y
Sbjct 201 STPQFLY 207
>sp|C4K0P3|ATP6_RICPU ATP synthase subunit a OS=Rickettsia peacockii
(strain Rustic) OX=562019 GN=atpB PE=3 SV=1
Length=242
Score = 37.0 bits (84), Expect = 4.9, Method: Composition-based stats.
Identities = 34/176 (19%), Positives = 64/176 (36%), Gaps = 22/176 (13%)
Query 3534 FDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTL 3593
D++ Q GV + KF +V ++L L + F + + FTL
Sbjct 70 ADMLNQNIGVKGR-KFIPLVFSLFIFILFCNLLGMT--------PYSFTATSHIIVTFTL 120
Query 3594 GIMAIAACAML-LVKHKHAFLCLF--------LLPSLATVAYFNMVYMPASWVMRIMTWL 3644
I+ ++ VKH FL LF L P + + F + P S +R+ +
Sbjct 121 AILVFLIVTIVGFVKHGLRFLTLFLPHGTPLWLAPLIIVIELFTYLARPVSLSLRLAANM 180
Query 3645 ELADTSLS---GYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYK 3697
L G+ + ++Y L + I++ A + +++ +Y
Sbjct 181 MAGHVLLKVIAGFTVS-LMIYLKFLPIPIMVILIGFEIFVAILQAYIFTILSCMYL 235
>sp|Q8U221|SYM_PYRFU Methionine--tRNA ligase OS=Pyrococcus furiosus
(strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) OX=186497
GN=metG PE=3 SV=1
Length=724
Score = 37.7 bits (86), Expect = 5.3, Method: Composition-based stats.
Identities = 22/129 (17%), Positives = 47/129 (36%), Gaps = 2/129 (2%)
Query 250 EHQTPFEIKSAKKFDTFKGECPKFVFPLNSKVKVIQPRVEKKKTEGFMGRIRSVYPVASP 309
EH TP ++ + + + +F + + + ++ + R
Sbjct 51 EHGTPISFRALNEKRSPREIVDEFHEHIKTAFQRVKISFDYFGRTELPVHYRLSQEFFLK 110
Query 310 QECNNMHLSTLMKCNHCDEVS-WQTCDFLKATCEHCGTENLVIEGPTTCGY-LPTNAVVK 367
N + + K +C+ + F+ TC +CG EN + CG L +++
Sbjct 111 ALENGYLVKKVTKQAYCEHDKRFLPDRFVIGTCPYCGAENQRGDQCEVCGRPLTPEILIE 170
Query 368 MPCPACQDP 376
C C++P
Sbjct 171 PRCAFCKNP 179
>sp|A8GQF6|ATP6_RICRS ATP synthase subunit a OS=Rickettsia rickettsii
(strain Sheila Smith) OX=392021 GN=atpB PE=3 SV=1
Length=242
Score = 37.0 bits (84), Expect = 5.6, Method: Composition-based stats.
Identities = 34/176 (19%), Positives = 64/176 (36%), Gaps = 22/176 (13%)
Query 3534 FDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTL 3593
D++ Q GV + KF +V ++L L + F + + FTL
Sbjct 70 ADMLNQNIGVKGR-KFIPLVFSLFIFILFCNLLGMT--------PYSFTATSHIIVTFTL 120
Query 3594 GIMAIAACAML-LVKHKHAFLCLF--------LLPSLATVAYFNMVYMPASWVMRIMTWL 3644
I+ ++ VKH FL LF L P + + F + P S +R+ +
Sbjct 121 AILVFLIVTIVGFVKHGLRFLTLFLPHGTPLWLAPLMIVIELFTYLARPVSLSLRLAANM 180
Query 3645 ELADTSLS---GYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYK 3697
L G+ + ++Y L + I++ A + +++ +Y
Sbjct 181 MAGHVLLKVIAGFTVS-LMIYLKFLPIPIMVILIGFEIFVAILQAYIFTILSCMYL 235
>sp|B0BVU2|ATP6_RICRO ATP synthase subunit a OS=Rickettsia rickettsii
(strain Iowa) OX=452659 GN=atpB PE=3 SV=1
Length=242
Score = 37.0 bits (84), Expect = 5.6, Method: Composition-based stats.
Identities = 34/176 (19%), Positives = 64/176 (36%), Gaps = 22/176 (13%)
Query 3534 FDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTL 3593
D++ Q GV + KF +V ++L L + F + + FTL
Sbjct 70 ADMLNQNIGVKGR-KFIPLVFSLFIFILFCNLLGMT--------PYSFTATSHIIVTFTL 120
Query 3594 GIMAIAACAML-LVKHKHAFLCLF--------LLPSLATVAYFNMVYMPASWVMRIMTWL 3644
I+ ++ VKH FL LF L P + + F + P S +R+ +
Sbjct 121 AILVFLIVTIVGFVKHGLRFLTLFLPHGTPLWLAPLMIVIELFTYLARPVSLSLRLAANM 180
Query 3645 ELADTSLS---GYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYK 3697
L G+ + ++Y L + I++ A + +++ +Y
Sbjct 181 MAGHVLLKVIAGFTVS-LMIYLKFLPIPIMVILIGFEIFVAILQAYIFTILSCMYL 235
>sp|Q4WFQ4|ABCH_ASPFU ABC multidrug transporter H OS=Aspergillus
fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100
/ Af293) OX=330879 GN=abcH PE=1 SV=2
Length=1424
Score = 37.7 bits (86), Expect = 6.1, Method: Composition-based stats.
Identities = 31/175 (18%), Positives = 66/175 (38%), Gaps = 16/175 (9%)
Query 3661 MYASALVLLILMTARTVYDDAARRVWTLMNVITLVYKVYYGNALDQAISMWALVISVTSN 3720
MY+ + L+ + Y ++ + Y V + + D+A +++ +++
Sbjct 1196 MYSWVAFVTALIVSEFPYLCVCAVLYFVC----WYYTVGFPSDSDKAGAIFFIMLCYEFL 1251
Query 3721 YSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRY 3780
Y+G+ I A F + PL+ T + +++ Y + Y+ LN +
Sbjct 1252 YTGIGQFIAAYAPNATFAALT-NPLILGTLVSFCGVLVPYAQIQAFWR-YW--IYWLNPF 1307
Query 3781 -----FRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPCI 3830
L V+D V +E + P + A L+ L G+G + +
Sbjct 1308 NYLMGSMLVFSVFDTDVKCKEGEFAV---FDTPNGTTCADYLSTYLQGVGSRANL 1359
>sp|Q5I0E9|S47A1_RAT Multidrug and toxin extrusion protein 1 OS=Rattus
norvegicus OX=10116 GN=Slc47a1 PE=1 SV=1
Length=566
Score = 37.3 bits (85), Expect = 6.3, Method: Composition-based stats.
Identities = 46/294 (16%), Positives = 93/294 (32%), Gaps = 48/294 (16%)
Query 3523 GSTILEDEFTPFDVVRQCS---GVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSL 3579
G + D Q GV Q I+ F+ + IL+ Q
Sbjct 90 GLSSACDTLISQTYGSQNLKHVGVILQRG-TLILLLCCFPCWALFINTEQILLLFRQDPD 148
Query 3580 FFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMR 3639
+ + + F I A+ A + ++ K+ +LP + T N+V A+++
Sbjct 149 VSRLTQTYVMVF---IPALPAAFLYTLQVKYLLNQGIVLPQVITGIAANLVNALANYLFL 205
Query 3640 IMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYDD-------------AARRVW 3686
L + ++L+ + +A A+ L + + R ++ A+
Sbjct 206 HQLHLGVMGSALANTISQ----FALAIFLFLYILWRKLHHATWGGWSWECLQDWASFLQL 261
Query 3687 TLMNVITLVYKVY---YGNALDQAISMWALVISVTSNYSGVVTTIMFLARAIVFVCVEYY 3743
+ +++ L + + G+ L + M L Y + M A V V
Sbjct 262 AIPSMLMLCIEWWAYEVGSFLSGILGMVELGAQSI-TYELAIIVYMIPAGFSVAANVRVG 320
Query 3744 PLL------------------FITGNTLQCIMLVYC--FLGYCCCCYFGLFCLL 3777
L C++L+ C +GY + + L+
Sbjct 321 NALGAGNIDQAKKSSAISLIVTELFAVTFCVLLLGCKDLVGYIFTTDWDIVALV 374
>sp|A1SSX2|RNFD_PSYIN Ion-translocating oxidoreductase complex
subunit D OS=Psychromonas ingrahamii (strain DSM 17664 / CCUG
51855 / 37) OX=357804 GN=rnfD PE=3 SV=1
Length=350
Score = 37.0 bits (84), Expect = 6.3, Method: Composition-based stats.
Identities = 23/174 (13%), Positives = 51/174 (29%), Gaps = 19/174 (11%)
Query 3479 YEPLTQDHVDILGPLSAQTGIAVLDMCAALKELLQNGMNGRTILGSTILEDEFTPFDVVR 3538
+ T D + + G+++ +++ L NG I S + +
Sbjct 163 FTGSTLDGYSVAQLSVSIDGLSMATPLNTVRDALHNGFTVTEIFNSVQFK-----ASSWQ 217
Query 3539 QCSGVT---FQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGI 3595
Q + G + K HW + + + ++ + G
Sbjct 218 QIYWINGAFLAGGLILLFKRIVHWHIPMSFLLGIGIFSFIAFAYSPDLNAPPLFHLFSGA 277
Query 3596 MAIAACAML--------LVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIM 3641
+ A +L VK + + LL + V N+ P + ++
Sbjct 278 TMLGAFFILSDPVSASTTVKGRILYA---LLIAFIVVIIRNVGGYPDAVAFAVL 328
>sp|Q00167|VG78_ICHVA Putative zinc-binding protein ORF78 OS=Ictalurid
herpesvirus 1 (strain Auburn) OX=766178 GN=ORF78 PE=4
SV=1
Length=400
Score = 37.0 bits (84), Expect = 6.5, Method: Composition-based stats.
Identities = 23/94 (24%), Positives = 38/94 (40%), Gaps = 10/94 (11%)
Query 2912 DTNLLEGSISYSELRPDTRYVLMDGSIIQF--PNTYL---EGSVRVVTTFD--AEYCRHG 2964
DT ++ G S +RPD+ + ++F P +G T C
Sbjct 32 DTGIVPGLRVESSVRPDSITNFRRLAAVKFKNPEVMECGGKGGCEECKTRPALMLNC--- 88
Query 2965 TCERSEVGICLSTSGRWVLNNEHYRALSGVFCGV 2998
C+ ++V ICL R V ++ +R + V CG
Sbjct 89 DCDTAKVPICLGCKPRAVRDHPCFRNRTCVSCGT 122
>sp|Q68XQ1|ATP6_RICTY ATP synthase subunit a OS=Rickettsia typhi
(strain ATCC VR-144 / Wilmington) OX=257363 GN=atpB PE=3
SV=1
Length=242
Score = 36.6 bits (83), Expect = 6.8, Method: Composition-based stats.
Identities = 23/150 (15%), Positives = 54/150 (36%), Gaps = 13/150 (9%)
Query 3560 MLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAML-LVKHKHAFLCLF-- 3616
++ + +L F + + FTL ++ ++ +KH +FL LF
Sbjct 87 LVFSLFIFILFCNLLGMTPYSFTATSHIIVTFTLALLIFLTVTIVGFIKHGMSFLTLFLP 146
Query 3617 ------LLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLS---GYRLKDCVMYASALV 3667
L P + + F + P S +R+ + L G+ + ++Y L
Sbjct 147 QGTPVWLAPLMIVIELFTYLAKPVSLSLRLAANMMAGHVLLKVIAGFTVS-LMIYLKFLP 205
Query 3668 LLILMTARTVYDDAARRVWTLMNVITLVYK 3697
+ +++ A + +++ +Y
Sbjct 206 IPLIVILIGFEIFVAILQAYIFTILSCMYL 235
>sp|J8HQ06|GAJB_BACC6 Gabija protein GajB OS=Bacillus cereus (strain
VD045) OX=1053225 GN=gajB PE=1 SV=1
Length=494
Score = 37.0 bits (84), Expect = 7.7, Method: Composition-based stats.
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query 5833 TVDSSQGSEYDYVIFTQTTETAH-SCNVNRFNVAITRAKIGILCIMSDRDLYDKLQ--FT 5889
TV S++G E++ VI T + H + + N VA TRAK ++ IM ++ D ++
Sbjct 424 TVHSAKGLEFNQVIITASDYNVHYNRDTNEHYVATTRAKDKLIVIMDNKKYSDYIETLMK 483
Query 5890 SLEIPRRNVA 5899
L+I +
Sbjct 484 ELKIKNIIKS 493
>sp|Q4UNH7|ATP6_RICFE ATP synthase subunit a OS=Rickettsia felis
(strain ATCC VR-1525 / URRWXCal2) OX=315456 GN=atpB PE=3
SV=1
Length=242
Score = 36.2 bits (82), Expect = 7.9, Method: Composition-based stats.
Identities = 33/176 (19%), Positives = 64/176 (36%), Gaps = 22/176 (13%)
Query 3534 FDVVRQCSGVTFQGKFKKIVKGTHHWMLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTL 3593
D++ Q GV + KF +V ++L L + F + + FTL
Sbjct 70 ADMLNQNIGVKGR-KFIPLVFSLFIFILFCNLLGMT--------PYSFTATSHIIVTFTL 120
Query 3594 GIMAIAACAML-LVKHKHAFLCLF--------LLPSLATVAYFNMVYMPASWVMRIMTWL 3644
I+ ++ VKH FL LF L P + + F + P S +R+ +
Sbjct 121 AILVFLTVTIVGFVKHGLRFLTLFLPHGTPLWLAPLMIVIELFTYLARPVSLSLRLAANM 180
Query 3645 ELADTSLS---GYRLKDCVMYASALVLLILMTARTVYDDAARRVWTLMNVITLVYK 3697
L G+ + ++Y L + +++ A + +++ +Y
Sbjct 181 MAGHVLLKVIAGFTVS-LMIYLKFLPIPLMVILIGFEIFVAILQAYIFTILSCMYL 235
>sp|P06011|1A_CMVQ Replication protein 1a OS=Cucumber mosaic virus
(strain Q) OX=12310 GN=ORF1a PE=3 SV=1
Length=991
Score = 37.0 bits (84), Expect = 8.4, Method: Composition-based stats.
Identities = 58/303 (19%), Positives = 107/303 (35%), Gaps = 50/303 (17%)
Query 5578 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPA 5637
S + G G GK+ +++ PS I+ TA +A D
Sbjct 708 ISQVDGVAGCGKTTAI--KSMFNPSTDIIVTANKKSAQDV-------------------- 745
Query 5638 RARVECFDKFKVNSTLEQYVFC------TVNALPETTADIVVFDEISMATNYDLSVVNAR 5691
+ FK + E F +N P + V+ DE+ + L V ++
Sbjct 746 -----RYALFKSTDSKEACAFVRTADSILLNDCPTVSR--VLVDEVVLLHFGQLCAVMSK 798
Query 5692 LRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVD 5751
L A + GD Q + + + + +L+ D T R P ++V
Sbjct 799 LHAVRALCFGDSEQ-------IAFSSRDASFDMRFSKLIPDETSDA--DTTFRSPQDVVP 849
Query 5752 TVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAV 5811
V + K + K + + + +T ++++ ++ R ++T A + A
Sbjct 850 LVRLMATKALPKGTRTKYSDGAQSKVRKSVTSRAVASVSLVELDPTRFYITMTQADK-AS 908
Query 5812 FISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN---VAITR 5868
I+ N + +TV SQG D+V + T +F+ VA+TR
Sbjct 909 LITRAKELNLPKAFYTD-RIKTVHESQGISEDHVTLVRLKSTKCDL-FKKFSYCLVAVTR 966
Query 5869 AKI 5871
K+
Sbjct 967 HKV 969
>sp|Q85BG0|NU4C_ANTAG NAD(P)H-quinone oxidoreductase chain 4,
chloroplastic OS=Anthoceros angustus OX=48387 GN=ndhD PE=2 SV=2
Length=501
Score = 37.0 bits (84), Expect = 8.8, Method: Composition-based stats.
Identities = 34/250 (14%), Positives = 76/250 (30%), Gaps = 28/250 (11%)
Query 3598 IAACAMLLVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLK 3657
+ M L+ H H+ P L + +VY S + + + S
Sbjct 261 LIRINMELLSHAHSIFA----PWLVVIGAIQIVY---SALTSLSQLNLKRRIAYSSVSHM 313
Query 3658 DCVMYASALVLLILMT---ARTVYDDAARRVWTLMNVITL-----VYKVYYGNALDQAIS 3709
V+ I + + + +T ++ G
Sbjct 314 GFVLIGIGSTTDIGVNGAILQMISHGLIGAALFFSAGVTYDRTRTLFLNQMGGIATSIPK 373
Query 3710 MWALVISVTSNYSGVVTTIMFLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCC 3769
++ + S + + F+A ++F+ + + ++++ G
Sbjct 374 IFTMFSSFSMASLALPGLSGFVAELMIFLGIVSSQNFSFLF---KVVIIIVAATGIILTP 430
Query 3770 YFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKSSIDAFKLNIKLLGIGGKPC 3829
+ L +L + F Y Y + Y+ G P+ L ++GIG P
Sbjct 431 IY-LLSMLRQMF------YGYRIIKNLTSYVTDAG---PREIFIFICLFFPIIGIGFYPK 480
Query 3830 IKVATVQSKM 3839
+ ++ SK+
Sbjct 481 LVLSLSNSKV 490
>sp|O40976|1A_CMVNT Replication protein 1a OS=Cucumber mosaic
virus (strain NT9) OX=117124 GN=ORF1a PE=3 SV=1
Length=993
Score = 37.0 bits (84), Expect = 9.0, Method: Composition-based stats.
Identities = 56/298 (19%), Positives = 105/298 (35%), Gaps = 39/298 (13%)
Query 5578 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPA 5637
S + G G GK+ +++ PS ++ TA +A D + C+ +
Sbjct 709 ISQVDGVAGCGKTTAI--KSIFEPSTDMIVTANKKSAQDVRMALFKSSDSKEACTFV--- 763
Query 5638 RARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHY 5697
T + + N P + V+ DE+ + L V ++L+A
Sbjct 764 -------------RTADSVLL---NECPTVSR--VLVDEVVLLHFGQLCAVMSKLKAVRA 805
Query 5698 VYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALV 5757
+ GD Q + + + + +++ D T R P ++V V +
Sbjct 806 ICFGDSEQ-------IAFSSRDASFDMRFSKIIPDETSDA--DTTFRSPQDVVPLVRLMA 856
Query 5758 YDNKLK-AHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5816
K H + + K +T +++ + R ++T A + A IS
Sbjct 857 TKALPKGTHSKYTKWVSQSKVKRSVTSRAIASVTLVDLDSSRFYITMTQADK-ASLISRA 915
Query 5817 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN---VAITRAKI 5871
N + +TV SQG D+V + T +F+ VA+TR K+
Sbjct 916 KEMN-LPKTFWNERIKTVHESQGISEDHVTLVRLKSTKCDL-FKQFSYCLVALTRHKV 971
>sp|P17769|1A_CMVFN Replication protein 1a OS=Cucumber mosaic
virus (strain FNY) OX=12307 GN=ORF1a PE=3 SV=2
Length=993
Score = 37.0 bits (84), Expect = 9.2, Method: Composition-based stats.
Identities = 56/298 (19%), Positives = 105/298 (35%), Gaps = 39/298 (13%)
Query 5578 YSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPA 5637
S + G G GK+ +++ PS ++ TA +A D + C+ +
Sbjct 709 ISQVDGVAGCGKTTAI--KSIFEPSTDMIVTANKKSAQDVRMALFKSSDSKEACTFV--- 763
Query 5638 RARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHY 5697
T + + N P + V+ DE+ + L V ++L+A
Sbjct 764 -------------RTADSVLL---NECPTVSR--VLVDEVVLLHFGQLCAVMSKLKAVRA 805
Query 5698 VYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALV 5757
+ GD Q + + + + +++ D T R P ++V V +
Sbjct 806 ICFGDSEQ-------IAFSSRDASFDMRFSKIIPDETSDA--DTTFRSPQDVVPLVRLMA 856
Query 5758 YDNKLK-AHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPY 5816
K H + + K +T +++ + R ++T A + A IS
Sbjct 857 TKALPKGTHSKYTKWVSQSKVKRSVTSRAIASVTLVDLDSSRFYITMTQADK-ASLISRA 915
Query 5817 NSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFN---VAITRAKI 5871
N + +TV SQG D+V + T +F+ VA+TR K+
Sbjct 916 KEMN-LPKTFWNERIKTVHESQGISEDHVTLVRLKSTKCDL-FKQFSYCLVALTRHKV 971
>sp|F4KIB2|TMN8_ARATH Transmembrane 9 superfamily member 8 OS=Arabidopsis
thaliana OX=3702 GN=TMN8 PE=2 SV=1
Length=648
Score = 37.0 bits (84), Expect = 9.3, Method: Composition-based stats.
Identities = 23/151 (15%), Positives = 50/151 (33%), Gaps = 19/151 (13%)
Query 3011 LVQPVGALDVSASVVAGGI-IAILVTCAAYYFMKFRRVFGEYNHVVAANALLFLMSFTI- 3068
+ PV ++ + + G + I + + + +F +FG + +V ++ T+
Sbjct 502 YMNPVFSILIGGILPFGAVFIELFFILTSIWLNQFYYIFG-FLFLVFVILIVTCAEITVV 560
Query 3069 LCLVP-----------AYSFLPGVYSVFYLYLTFYFTNDVSFLAHLQWFAMFSPIVPFWI 3117
LC +Y +LY TFYF + + F ++
Sbjct 561 LCYFQLCSEDYLWWWRSYLTSGSSALYLFLYATFYFFTKLQITKLVSAMLYFG-----YM 615
Query 3118 TAIYVFCISLKHCHWFFNNYLRKRVMFNGVT 3148
L F+ R++++ V
Sbjct 616 LIASYAFFVLTGTIGFYACLWFTRLIYSSVK 646
>sp|Q91ZC7|MRGA5_MOUSE Mas-related G-protein coupled receptor
member A5 OS=Mus musculus OX=10090 GN=Mrgpra5 PE=2 SV=2
Length=304
Score = 36.2 bits (82), Expect = 9.8, Method: Composition-based stats.
Identities = 42/261 (16%), Positives = 85/261 (33%), Gaps = 34/261 (13%)
Query 3560 MLLTFLTSLLILVQSTQWSLFFFVYENAFLPFTLGIMAIAACAMLLVKHKHAFLCLFLLP 3619
M++ F + W L F ++ NAF + +A+A LL H + LL
Sbjct 18 MIIIFRLVGMTGNAIVFWLLGFSLHRNAF-SVYILNLALADFVFLLC---HIIDSMLLL- 72
Query 3620 SLATVAYFNMVYMPASWVMRIMTWLELADTSLSGYRLKDCVMYASALVLLILMTARTVYD 3679
TV Y N ++ + + + ++G + + L +L + R +
Sbjct 73 --LTVFYPNNIFSGYFYTI-------MTVPYIAGLSMLSAISTELCLSVLCPIWYRCHHP 123
Query 3680 DAARR-----VWTLMNVITLVYKVY-----YGNALDQAISMWALVISVTSNYSGVVTTIM 3729
+ +W L ++ ++ + + D+ + VV +
Sbjct 124 EHTSTVMCAAIWVLPLLVCILNRYFCSFLDINYNNDKQCLASNFFTRAYLMFLFVVLCLS 183
Query 3730 FLARAIVFVCVEYYPLLFITGNTLQCIMLVYCFLGYCCCCYFGLFCLLNRYFRLTLGVYD 3789
+A C L T+ +L + G Y+ L + F L +D
Sbjct 184 SMALLARLFCGTGQMKLTRLYVTIMLTVLGFLLCGLPFVIYYFLLFNIKDGFCL----FD 239
Query 3790 YLVSTQEFRYMNSQGLLPPKS 3810
+ YM++ L +
Sbjct 240 FRF------YMSTHVLTAINN 254
Lambda K H a alpha
0.318 0.134 0.377 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0411 0.140 1.90 42.6 43.6
Effective search space used: 870231075712
Database: uniprot_sprot.fasta
Posted date: Apr 3, 2024 12:05 PM
Number of letters in database: 206,678,396
Number of sequences in database: 571,282
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40