PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,282 sequences; 206,678,396 total letters
Results from round 1
Query= sp|P09958|FURIN_HUMAN Furin OS=Homo sapiens OX=9606 GN=FURIN PE=1
SV=2
Length=794
Score E
Sequences producing significant alignments: (Bits) Value
sp|P09958|FURIN_HUMAN Furin OS=Homo sapiens OX=9606 GN=FURIN PE=1... 1652 0.0
sp|P23188|FURIN_MOUSE Furin OS=Mus musculus OX=10090 GN=Furin PE=... 1508 0.0
sp|Q28193|FURIN_BOVIN Furin OS=Bos taurus OX=9913 GN=FURIN PE=1 SV=1 1503 0.0
sp|P23377|FURIN_RAT Furin OS=Rattus norvegicus OX=10116 GN=Furin ... 1495 0.0
sp|P29119|FURI1_XENLA Furin-1 OS=Xenopus laevis OX=8355 GN=furin ... 1167 0.0
sp|Q6UW60|PCSK4_HUMAN Proprotein convertase subtilisin/kexin type... 773 0.0
sp|Q78EH2|PCSK4_RAT Proprotein convertase subtilisin/kexin type 4... 716 0.0
sp|P29121|PCSK4_MOUSE Proprotein convertase subtilisin/kexin type... 697 0.0
sp|Q04592|PCSK5_MOUSE Proprotein convertase subtilisin/kexin type... 669 0.0
sp|Q63415|PCSK6_RAT Proprotein convertase subtilisin/kexin type 6... 668 0.0
sp|Q92824|PCSK5_HUMAN Proprotein convertase subtilisin/kexin type... 668 0.0
sp|P41413|PCSK5_RAT Proprotein convertase subtilisin/kexin type 5... 667 0.0
sp|P29122|PCSK6_HUMAN Proprotein convertase subtilisin/kexin type... 659 0.0
sp|P26016|FUR11_DROME Furin-like protease 1, isoforms 1/1-X/2 OS=... 647 0.0
sp|O17798|FKPC1_CAEEL Furin-like protease kpc-1 OS=Caenorhabditis... 646 0.0
sp|P30430|FUR1C_DROME Furin-like protease 1, isoform 1-CRR OS=Dro... 643 0.0
sp|Q9NJ15|PCSK5_BRACL Proprotein convertase subtilisin/kexin type... 631 0.0
sp|P30432|FUR2_DROME Furin-like protease 2 OS=Drosophila melanoga... 603 0.0
sp|P63239|NEC1_MOUSE Neuroendocrine convertase 1 OS=Mus musculus ... 588 0.0
sp|P63240|NEC1_MUSCO Neuroendocrine convertase 1 OS=Mus cookii OX... 588 0.0
sp|P28840|NEC1_RAT Neuroendocrine convertase 1 OS=Rattus norvegic... 582 0.0
sp|P29120|NEC1_HUMAN Neuroendocrine convertase 1 OS=Homo sapiens ... 582 0.0
sp|Q9GLR1|NEC1_BOVIN Neuroendocrine convertase 1 OS=Bos taurus OX... 579 0.0
sp|P51559|BLI4_CAEEL Endoprotease bli-4 OS=Caenorhabditis elegans... 538 5e-178
sp|A0A044RE18|BLI_ONCVO Endoprotease bli OS=Onchocerca volvulus O... 528 3e-177
sp|Q5REC2|NEC2_PONAB Neuroendocrine convertase 2 OS=Pongo abelii ... 511 2e-171
sp|P16519|NEC2_HUMAN Neuroendocrine convertase 2 OS=Homo sapiens ... 511 2e-171
sp|Q03333|NEC2_PIG Neuroendocrine convertase 2 OS=Sus scrofa OX=9... 509 2e-170
sp|Q9VBC7|NEC2_DROME Neuroendocrine convertase 2 OS=Drosophila me... 507 1e-169
sp|Q9GLR0|NEC2_BOVIN Neuroendocrine convertase 2 OS=Bos taurus OX... 506 1e-169
sp|P21661|NEC2_MOUSE Neuroendocrine convertase 2 OS=Mus musculus ... 506 1e-169
sp|P28841|NEC2_RAT Neuroendocrine convertase 2 OS=Rattus norvegic... 505 4e-169
sp|P29145|NECB_HYDVU PC3-like endoprotease variant B OS=Hydra vul... 498 2e-165
sp|P29146|NECA_HYDVU PC3-like endoprotease variant A OS=Hydra vul... 499 1e-164
sp|G5ECN9|NEC2_CAEEL Neuroendocrine convertase 2 OS=Caenorhabditi... 493 4e-164
sp|Q62849|PCSK7_RAT Proprotein convertase subtilisin/kexin type 7... 400 2e-126
sp|Q61139|PCSK7_MOUSE Proprotein convertase subtilisin/kexin type... 397 1e-125
sp|Q16549|PCSK7_HUMAN Proprotein convertase subtilisin/kexin type... 395 6e-125
sp|Q09175|KRP1_SCHPO Dibasic-processing endoprotease OS=Schizosac... 385 7e-122
sp|P09231|KEX1A_KLULA Protease KEX1 OS=Kluyveromyces lactis (stra... 375 2e-117
sp|P13134|KEX2_YEAST Kexin OS=Saccharomyces cerevisiae (strain AT... 353 3e-108
sp|O13359|KEX2_CANAW Kexin OS=Candida albicans (strain WO-1) OX=2... 349 7e-106
sp|P42781|XPR6_YARLI Dibasic-processing endoprotease OS=Yarrowia ... 349 2e-105
sp|P91863|AEX5_CAEEL Endoprotease aex-5 OS=Caenorhabditis elegans... 239 1e-68
sp|P23916|PRCA_TRIV2 Calcium-dependent protease OS=Trichormus var... 113 1e-24
sp|Q59149|PRCA_NOSS1 Calcium-dependent protease OS=Nostoc sp. (st... 108 4e-23
sp|P42779|BPRV_DICNO Extracellular basic protease OS=Dichelobacte... 97.1 1e-19
sp|Q9L5A4|ASP_AERSO Aeromonas extracellular serine protease OS=Ae... 94.7 1e-18
sp|P42780|BPRX_DICNO Extracellular subtilisin-like protease OS=Di... 85.5 6e-16
sp|Q00139|VG47_ICHVA Subtilisin-like protease OS=Ictalurid herpes... 74.3 9e-13
sp|P23314|EXPR_XANCP Extracellular protease OS=Xanthomonas campes... 73.6 4e-12
sp|P16396|SUBE_BACSU Minor extracellular protease Epr OS=Bacillus... 68.6 1e-10
sp|P04072|THET_THEVU Thermitase OS=Thermoactinomyces vulgaris OX=... 66.6 1e-10
sp|P29143|HLY_NATA1 Halolysin OS=Natrialba asiatica (strain ATCC ... 66.2 6e-10
sp|P29141|SUBV_BACSU Minor extracellular protease Vpr OS=Bacillus... 65.5 1e-09
sp|P29599|SUBB_LEDLE Subtilisin BL OS=Lederbergia lenta OX=1467 P... 61.6 5e-09
sp|P04189|SUBT_BACSU Subtilisin E OS=Bacillus subtilis (strain 16... 62.0 8e-09
sp|P35835|SUBN_BACNA Subtilisin NAT OS=Bacillus subtilis subsp. n... 62.0 9e-09
sp|P29142|SUBT_GEOSE Subtilisin J OS=Geobacillus stearothermophil... 60.8 2e-08
sp|P00783|SUBT_BACSA Subtilisin amylosacchariticus OS=Bacillus su... 60.8 2e-08
sp|P27693|ELYA_ALKAL Alkaline protease OS=Alkalihalobacillus alca... 60.1 3e-08
sp|Q99405|PRTM_SHOC1 M-protease OS=Shouchella clausii (strain KSM... 59.3 5e-08
sp|P07518|SUBT_BACPU Subtilisin OS=Bacillus pumilus OX=1408 GN=ap... 58.2 7e-08
sp|P41362|ELYA_SHOCL Alkaline protease OS=Shouchella clausii OX=7... 58.2 2e-07
sp|P29600|SUBS_LEDLE Subtilisin Savinase OS=Lederbergia lenta OX=... 57.0 2e-07
sp|Q45670|THES_BACSJ Thermophilic serine proteinase OS=Bacillus s... 57.8 2e-07
sp|P16588|PROA_VIBAL Alkaline serine exoprotease A OS=Vibrio algi... 57.8 3e-07
sp|P00782|SUBT_BACAM Subtilisin BPN' OS=Bacillus amyloliquefacien... 57.4 3e-07
sp|P20724|ELYA_BACYA Alkaline elastase YaB OS=Bacillus sp. (strai... 57.0 3e-07
sp|I3R794|HLY_HALMT Halolysin OS=Haloferax mediterranei (strain A... 57.4 3e-07
sp|O31788|APRX_BACSU Serine protease AprX OS=Bacillus subtilis (s... 56.2 7e-07
sp|P11018|ISP1_BACSU Major intracellular serine protease OS=Bacil... 55.1 1e-06
sp|P29805|PRTT_SERMA Extracellular serine protease OS=Serratia ma... 53.9 5e-06
sp|Q8IHZ5|SUB2_PLAF7 Subtilisin-like protease 2 OS=Plasmodium fal... 53.9 7e-06
sp|Q9RYM8|SUB2_DEIRA Probable subtilase-type serine protease DR_A... 53.5 7e-06
sp|P81719|PIIS_ACHLY Protease 2 small chain (Fragment) OS=Achromo... 47.0 1e-05
sp|P31339|ASPA_AERSA Microbial serine proteinase OS=Aeromonas sal... 51.6 3e-05
sp|O97364|SUB2_PLAFA Subtilisin-like protease 2 OS=Plasmodium fal... 51.6 3e-05
sp|P00780|SUBC_BACLI Subtilisin Carlsberg OS=Bacillus licheniform... 50.4 4e-05
sp|P25036|YSP3_YEAST Subtilisin-like protease 3 OS=Saccharomyces ... 50.1 7e-05
sp|P29139|ISP_PAEPO Intracellular serine protease OS=Paenibacillu... 49.3 7e-05
sp|P09489|PRTS_SERMA Extracellular serine protease OS=Serratia ma... 50.1 8e-05
sp|P41363|ELYA_HALH5 Thermostable alkaline protease OS=Halalkalib... 49.3 9e-05
sp|P29138|CUDP_METAN Cuticle-degrading protease OS=Metarhizium an... 49.3 1e-04
sp|W7K9M0|SUB1_PLAFO Subtilisin-like protease 1 OS=Plasmodium fal... 49.7 1e-04
sp|Q8I0V0|SUB1_PLAF7 Subtilisin-like protease 1 OS=Plasmodium fal... 49.7 1e-04
sp|O61142|SUB1_PLAFA Subtilisin-like protease 1 OS=Plasmodium fal... 49.7 1e-04
sp|P58371|SPM1_PYRO7 Subtilisin-like proteinase Spm1 OS=Pyricular... 47.4 5e-04
sp|L8G6I7|SUB1_PSED2 Subtilisin-like protease 1 OS=Pseudogymnoasc... 47.0 5e-04
sp|Q68GV9|ALP_LECPS Alkaline serine protease ver112 OS=Lecanicill... 45.8 0.001
sp|Q93LQ6|FLS_FERPE Fervidolysin OS=Fervidobacterium pennivorans ... 45.8 0.002
sp|Q9Y008|SUB2_PLAFP Subtilisin-like protease 2 OS=Plasmodium fal... 45.8 0.002
sp|Q80T14|FRAS1_MOUSE Extracellular matrix organizing protein FRA... 45.8 0.002
sp|P58502|TKSU_THEKO Tk-subtilisin OS=Thermococcus kodakarensis (... 45.1 0.002
sp|C5P4Z8|SUB8_COCP7 Subtilisin-like protease CPC735_031240 OS=Co... 45.1 0.002
sp|P09232|PRTB_YEAST Cerevisin OS=Saccharomyces cerevisiae (strai... 45.1 0.003
sp|P33295|PEPC_ASPNG Subtilisin-like serine protease pepC OS=Aspe... 44.7 0.003
sp|P87184|ALP2_ASPFU Alkaline protease 2 OS=Aspergillus fumigatus... 44.7 0.003
sp|B0Y473|ALP2_ASPFC Alkaline protease 2 OS=Aspergillus fumigatus... 44.7 0.003
sp|P00781|SUBD_BACLI Subtilisin DY OS=Bacillus licheniformis OX=1... 43.5 0.004
sp|L8FSM5|SUB2_PSED2 Subtilisin-like protease 2 OS=Pseudogymnoasc... 43.9 0.004
sp|P08594|AQL1_THEAQ Aqualysin-1 OS=Thermus aquaticus OX=271 GN=p... 43.9 0.005
sp|Q9P8G3|PEN18_PENRB Subtilisin-like serine protease Pen ch 18.0... 43.5 0.007
sp|D4AX50|SUB8_ARTBC Subtilisin-like protease 8 OS=Arthroderma be... 43.5 0.007
sp|P9WEW5|PCH18_PENRB Subtilisin-like serine protease Pen ch 18 O... 43.5 0.007
sp|P9WEW6|PCH18_PENCH Subtilisin-like serine protease EN45_078720... 43.5 0.007
sp|P06873|PRTK_PARAQ Proteinase K OS=Parengyodontium album OX=379... 43.1 0.008
sp|P54423|WPRA_BACSU Cell wall-associated protease OS=Bacillus su... 43.5 0.010
sp|C5PCB1|SUB4A_COCP7 Subtilisin-like protease CPC735_066880 OS=C... 42.7 0.010
sp|C5FII2|SUB8_ARTOC Subtilisin-like protease 8 OS=Arthroderma ot... 42.7 0.012
sp|P29140|ISP_SHOCL Intracellular alkaline protease OS=Shouchella... 42.4 0.013
sp|C5P9H3|SUB7D_COCP7 Subtilisin-like protease CPC735_005570 OS=C... 42.4 0.015
sp|P80146|SEPR_THESR Extracellular serine proteinase OS=Thermus s... 42.4 0.015
sp|Q07596|NISP_LACLL Nisin leader peptide-processing serine prote... 42.4 0.017
sp|Q9Y755|PENC2_PENCI Subtilisin-like serine protease Pen c 2 OS=... 42.0 0.018
sp|D4DKQ4|SUB8_TRIVH Subtilisin-like protease 8 OS=Trichophyton v... 42.0 0.020
sp|B3V0K8|CL401_COCLU Subtilisin-like serine protease Cur l 4.010... 42.0 0.020
sp|E4UTU7|SUB9_ARTGP Subtilisin-like protease 9 OS=Arthroderma gy... 41.6 0.024
sp|C5P6D1|SUB2A_COCP7 Subtilisin-like protease CPC735_023170 OS=C... 41.6 0.027
sp|C5FH27|SUB9_ARTOC Subtilisin-like protease 9 OS=Arthroderma ot... 41.2 0.033
sp|Q8SQJ3|SPL1_ENCCU Putative subtilisin-like proteinase 1 OS=Enc... 41.2 0.034
sp|B7ZK61|CH901_DAVTA Subtilisin-like serine protease Cla h 9.010... 41.2 0.035
sp|Q86XX4|FRAS1_HUMAN Extracellular matrix organizing protein FRA... 41.2 0.053
sp|P16397|SUBF_BACSU Bacillopeptidase F OS=Bacillus subtilis (str... 40.8 0.057
sp|P23653|PRTR_PARAQ Proteinase R OS=Parengyodontium album OX=379... 40.0 0.079
sp|Q5M7L6|RSPO2_XENTR R-spondin-2 OS=Xenopus tropicalis OX=8364 G... 39.3 0.080
sp|Q8BFU0|RSPO2_MOUSE R-spondin-2 OS=Mus musculus OX=10090 GN=Rsp... 39.3 0.095
sp|Q6UXX9|RSPO2_HUMAN R-spondin-2 OS=Homo sapiens OX=9606 GN=RSPO... 38.9 0.10
sp|L8GD75|SUB3_PSED2 Subtilisin-like protease 3 OS=Pseudogymnoasc... 39.7 0.11
sp|A1XIH0|SUB6_TRIEQ Subtilisin-like protease 6 OS=Trichophyton e... 39.3 0.14
sp|Q3ZEJ8|SUB6_TRITO Subtilisin-like protease 6 OS=Trichophyton t... 39.3 0.14
sp|Q32ZM1|RM201_RHOMI Subtilisin-like serine protease Rho m 2.010... 38.9 0.15
sp|D4B5N1|SUB9_ARTBC Subtilisin-like protease 9 OS=Arthroderma be... 38.9 0.16
sp|Q9Y749|PENC1_PENCI Subtilisin-like serine protease Pen c 1 OS=... 38.9 0.17
sp|Q9URR2|PEN13_PENRB Subtilisin-like serine protease Pen ch 13.0... 38.9 0.17
sp|D4D674|SUB9_TRIVH Subtilisin-like protease 9 OS=Trichophyton v... 38.9 0.18
sp|G1X8P8|SPAZ_ARTOA Cuticle-degrading serine protease OS=Arthrob... 38.9 0.18
sp|G3FNQ9|SPAZ_ORBOL Cuticle-degrading serine protease OS=Orbilia... 38.5 0.26
sp|C5PCX1|SUB7B_COCP7 Subtilisin-like protease CPC735_015300 OS=C... 37.4 0.49
sp|E4V2V9|SUB7_ARTGP Subtilisin-like protease 7 OS=Arthroderma gy... 37.4 0.58
sp|E4V4J8|SUB6_ARTGP Subtilisin-like protease 6 OS=Arthroderma gy... 37.0 0.62
sp|D4DIS6|SUB10_TRIVH Subtilisin-like protease 10 OS=Trichophyton... 37.0 0.88
sp|C5P5Q3|SUB9_COCP7 Subtilisin-like protease CPC735_033790 OS=Co... 36.6 1.0
sp|C5FJA5|SUB7_ARTOC Subtilisin-like protease 7 OS=Arthroderma ot... 36.2 1.1
sp|P9WEW3|PCH13_PENRB Subtilisin-like serine protease Pen ch 13 O... 36.2 1.3
sp|P9WEW4|PCH13_PENCH Subtilisin-like serine protease EN45_076310... 36.2 1.3
sp|P28842|SUBT_BACS9 Subtilisin OS=Bacillus sp. (strain TA39) OX=... 36.2 1.3
sp|Q1DFT5|POPC_MYXXD Subtilisin-like protease PopC OS=Myxococcus ... 35.8 1.6
sp|Q9UTS0|PSP3_SCHPO Subtilase-type proteinase psp3 OS=Schizosacc... 35.8 1.6
sp|Q5UE90|RSPO2_XENLA R-spondin-2 OS=Xenopus laevis OX=8355 GN=rs... 35.4 1.7
sp|Q92GM6|TGT_RICCN Queuine tRNA-ribosyltransferase OS=Rickettsia... 35.8 1.7
sp|C3PLJ4|TGT_RICAE Queuine tRNA-ribosyltransferase OS=Rickettsia... 35.8 1.7
sp|A8GTF4|TGT_RICRS Queuine tRNA-ribosyltransferase OS=Rickettsia... 35.4 1.8
sp|B0BUZ2|TGT_RICRO Queuine tRNA-ribosyltransferase OS=Rickettsia... 35.4 1.8
sp|C4K0T2|TGT_RICPU Queuine tRNA-ribosyltransferase OS=Rickettsia... 35.4 1.9
sp|D4APA9|SUB7_ARTBC Subtilisin-like protease 7 OS=Arthroderma be... 35.4 2.0
sp|D4CZQ4|SUB7_TRIVH Subtilisin-like protease 7 OS=Trichophyton v... 35.4 2.4
sp|C5FXZ6|SUB4_ARTOC Subtilisin-like protease 4 OS=Arthroderma ot... 35.4 2.4
sp|B8XGQ7|SUB4_TRITO Subtilisin-like protease 4 OS=Trichophyton t... 35.0 2.4
sp|A7UKV6|SUB4_TRIEQ Subtilisin-like protease 4 (Fragment) OS=Tri... 35.0 2.5
sp|R4IR27|ASES_SARSR Subtilisin-like serine protease AsES OS=Saro... 35.0 2.6
sp|D4D6Q4|SUB4_TRIVH Subtilisin-like protease 4 OS=Trichophyton v... 35.0 2.6
sp|Q5VJ74|SUB4_TRIVC Subtilisin-like protease 4 OS=Trichophyton v... 35.0 2.6
sp|Q64K33|SUB4_ARTBE Subtilisin-like protease 4 OS=Arthroderma be... 35.0 2.6
sp|D4AXW3|SUB4_ARTBC Subtilisin-like protease 4 OS=Arthroderma be... 35.0 2.6
sp|Q69F35|SUB4_TRIRU Subtilisin-like protease 4 OS=Trichophyton r... 35.0 2.7
sp|Q64K36|SUB7_ARTBE Subtilisin-like protease 7 OS=Arthroderma be... 35.0 2.8
sp|P15293|P2P_LACLC PII-type proteinase OS=Lactococcus lactis sub... 35.4 2.8
sp|P16271|P1P_LACLC PI-type proteinase OS=Lactococcus lactis subs... 35.4 2.8
sp|P15292|P3P_LACLS PIII-type proteinase OS=Lactococcus lactis su... 35.4 2.8
sp|Q0WUG6|SBT61_ARATH Subtilisin-like protease SBT6.1 OS=Arabidop... 35.4 2.9
sp|A9QY38|SBT4_LOTJA Subtilisin-like protease 4 OS=Lotus japonicu... 35.0 2.9
sp|C5FQI3|SUB6_ARTOC Subtilisin-like protease 6 OS=Arthroderma ot... 35.0 2.9
sp|Q5VJ71|SUB7_TRIVC Subtilisin-like protease 7 OS=Trichophyton v... 35.0 2.9
sp|Q02470|P2P_LACPA PII-type proteinase OS=Lacticaseibacillus par... 35.0 3.4
sp|P72186|PLS_PYRFU Pyrolysin OS=Pyrococcus furiosus (strain ATCC... 34.7 4.1
sp|Q4G063|CREL2_RAT Protein disulfide isomerase Creld2 OS=Rattus ... 34.3 4.2
sp|Q64K31|SUB6_ARTBE Subtilisin-like protease 6 OS=Arthroderma be... 34.3 4.2
sp|D4ALV9|SUB6_ARTBC Subtilisin-like protease 6 OS=Arthroderma be... 34.3 4.2
sp|B6VA86|SUB3_TRIEQ Subtilisin-like protease 3 OS=Trichophyton e... 34.3 4.3
sp|E4UN97|SUB3_ARTGP Subtilisin-like protease 3 OS=Arthroderma gy... 34.3 4.4
sp|B8XGQ6|SUB3_TRITO Subtilisin-like protease 3 OS=Trichophyton t... 34.3 4.5
sp|D4DLA2|SUB3_TRIVH Subtilisin-like protease 3 OS=Trichophyton v... 34.3 4.7
sp|Q5VJ75|SUB3_TRIVC Subtilisin-like protease 3 OS=Trichophyton v... 34.3 4.7
sp|Q64K34|SUB3_ARTBE Subtilisin-like protease 3 OS=Arthroderma be... 34.3 4.7
sp|D4AWY5|SUB3_ARTBC Subtilisin-like protease 3 OS=Arthroderma be... 34.3 4.7
sp|Q8J077|SUB6_TRISH Subtilisin-like protease 6 (Fragment) OS=Tri... 34.3 5.0
sp|P20015|PRTT_PARAQ Proteinase T (Fragment) OS=Parengyodontium a... 33.9 5.7
sp|E4UWA4|SUB4_ARTGP Subtilisin-like protease 4 OS=Arthroderma gy... 33.9 5.7
sp|P40903|ISP6_SCHPO Sexual differentiation process putative subt... 33.9 5.9
sp|Q4V7M2|CRE2B_XENLA Cysteine-rich with EGF-like domain protein ... 33.9 6.2
sp|Q2K7Z9|ANMK_RHIEC Anhydro-N-acetylmuramic acid kinase OS=Rhizo... 33.9 6.3
sp|Q69F57|SUB2_TRIRU Subtilisin-like protease 2 OS=Trichophyton r... 33.9 6.7
sp|C5NZT2|SUB4B_COCP7 Subtilisin-like protease CPC735_012930 OS=C... 33.9 7.1
sp|Q7T364|TPL2B_DANRE Tumor necrosis factor, alpha-induced protei... 33.1 7.1
sp|Q5XH36|CRE2A_XENLA Cysteine-rich with EGF-like domain protein ... 33.5 7.2
sp|Q8J0D7|SUB3_ARTOT Subtilisin-like protease 3 OS=Arthroderma ot... 33.5 8.6
sp|C5FMY5|SUB3_ARTOC Subtilisin-like protease 3 OS=Arthroderma ot... 33.5 8.6
sp|P0CY46|EGFR_APIME Epidermal growth factor receptor OS=Apis mel... 33.5 9.4
>sp|P09958|FURIN_HUMAN Furin OS=Homo sapiens OX=9606 GN=FURIN
PE=1 SV=2
Length=794
Score = 1652 bits (4278), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 794/794 (100%), Positives = 794/794 (100%), Gaps = 0/794 (0%)
Query 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI 60
MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI
Sbjct 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI 60
Query 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ
Sbjct 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP
Sbjct 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
Query 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL
Sbjct 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH
Sbjct 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
Query 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC
Sbjct 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV
Sbjct 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
Query 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH 480
SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH
Sbjct 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH 480
Query 481 ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD
Sbjct 481 ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
Query 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCE 600
EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCE
Sbjct 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCE 600
Query 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL 660
EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL
Sbjct 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL 660
Query 661 SCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGL 720
SCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGL
Sbjct 661 SCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGL 720
Query 721 SCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG 780
SCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG
Sbjct 721 SCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG 780
Query 781 RGERTAFIKDQSAL 794
RGERTAFIKDQSAL
Sbjct 781 RGERTAFIKDQSAL 794
>sp|P23188|FURIN_MOUSE Furin OS=Mus musculus OX=10090 GN=Furin
PE=1 SV=2
Length=793
Score = 1508 bits (3905), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 745/794 (94%), Positives = 760/794 (96%), Gaps = 1/794 (0%)
Query 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI 60
MELR WLLWVVAA G +VLLAADAQGQK+FTNTWAV IPGGPAVA+ VA+KHGF NLGQI
Sbjct 1 MELRSWLLWVVAAAGAVVLLAADAQGQKIFTNTWAVHIPGGPAVADRVAQKHGFHNLGQI 60
Query 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
FGDYYHFWHR VTKRSLSPHRPRHSRLQREPQV+WLEQQVAKRR KRDVYQEPTDPKFPQ
Sbjct 61 FGDYYHFWHRAVTKRSLSPHRPRHSRLQREPQVKWLEQQVAKRRAKRDVYQEPTDPKFPQ 120
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
QWYLSGVTQRDLNVK AWAQG+TGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP
Sbjct 121 QWYLSGVTQRDLNVKEAWAQGFTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
Query 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL
Sbjct 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH
Sbjct 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
Query 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC
Sbjct 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA+DWATNGVGRKV
Sbjct 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNADDWATNGVGRKV 420
Query 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH 480
SHSYGYGLLDAGAMVALAQNWTTVAPQRKCI++IL EPKDIGKRLEVRK VTACLGEPNH
Sbjct 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIVEILVEPKDIGKRLEVRKAVTACLGEPNH 480
Query 481 ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
ITRLEH QARLTLSYNRRGDLAIHL+SPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD
Sbjct 481 ITRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
Query 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCE 600
EDP+GEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGL PPESSGCKTLTSSQACVVCE
Sbjct 541 EDPAGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLSTPPESSGCKTLTSSQACVVCE 600
Query 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL 660
EG+SLHQKSCVQHCPPGF PQVLDTHYSTENDVE IRASVC PCHASCATCQGPA TDCL
Sbjct 601 EGYSLHQKSCVQHCPPGFIPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCL 660
Query 661 SCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGL 720
SCPSHASLDPVEQTCSRQSQSSRES PQQQPP L PEVE RL+AG L SHLPEV+AGL
Sbjct 661 SCPSHASLDPVEQTCSRQSQSSRESRPQQQPPALRPEVEMEPRLQAG-LASHLPEVLAGL 719
Query 721 SCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG 780
SC IVL+F VFL L SGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG
Sbjct 720 SCLIIVLIFGIVFLFLHRCSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG 779
Query 781 RGERTAFIKDQSAL 794
RGERTAFIKDQSAL
Sbjct 780 RGERTAFIKDQSAL 793
>sp|Q28193|FURIN_BOVIN Furin OS=Bos taurus OX=9913 GN=FURIN PE=1
SV=1
Length=797
Score = 1503 bits (3890), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 745/797 (93%), Positives = 757/797 (95%), Gaps = 3/797 (0%)
Query 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI 60
MELRPWL WVVAA G LVLL ADA+G+KVFTNTWAV IPGGPAVA+ VARKHGFLNLGQI
Sbjct 1 MELRPWLFWVVAAAGALVLLVADARGEKVFTNTWAVHIPGGPAVADRVARKHGFLNLGQI 60
Query 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
FGDYYHFWHR VTKRSLSPHR H+RLQREPQV+WLEQQVAKRR KRD+YQEPTDPKFPQ
Sbjct 61 FGDYYHFWHRAVTKRSLSPHRLGHNRLQREPQVKWLEQQVAKRRAKRDIYQEPTDPKFPQ 120
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
QWYLSGVTQRDLNVK AWAQGYTG GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP
Sbjct 121 QWYLSGVTQRDLNVKEAWAQGYTGRGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
Query 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL
Sbjct 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
GLNPNHIHIYSASWGPEDDGKTVDGPA LAEEAFFRGVSQGRGGLGSIFVWASGNGGREH
Sbjct 241 GLNPNHIHIYSASWGPEDDGKTVDGPAHLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
Query 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC
Sbjct 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
TESHTGTSA APLAAGIIALTLEANKNLTWRDMQHLVV+TSKPAHLNANDWATNGVGRKV
Sbjct 361 TESHTGTSAFAPLAAGIIALTLEANKNLTWRDMQHLVVRTSKPAHLNANDWATNGVGRKV 420
Query 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH 480
SHSYGYGLLDAGAMVALAQNWTTVAPQRKC IDILTEPKDIGKRLEVRKTVTACLGEP+H
Sbjct 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCTIDILTEPKDIGKRLEVRKTVTACLGEPSH 480
Query 481 ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD
Sbjct 481 ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
Query 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCE 600
EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLP PPES GCKTLTSSQACVVCE
Sbjct 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPTPPESIGCKTLTSSQACVVCE 600
Query 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL 660
EGFSLHQK+CVQHCPPGFAPQVLDTHYSTENDVE IRASVC PCHASCATCQGPA TDCL
Sbjct 601 EGFSLHQKNCVQHCPPGFAPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCL 660
Query 661 SCPSHASLDPVEQTC---SRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVV 717
SCPSHASLDPVEQTC S+ S+ S + P P P EV RLRA LLPSHLPEVV
Sbjct 661 SCPSHASLDPVEQTCSRQSQSSRESHQQQPPPPPRPPPAEVATEPRLRADLLPSHLPEVV 720
Query 718 AGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEE 777
AGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEE
Sbjct 721 AGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEE 780
Query 778 DEGRGERTAFIKDQSAL 794
DEGRGERTAFIKDQSAL
Sbjct 781 DEGRGERTAFIKDQSAL 797
>sp|P23377|FURIN_RAT Furin OS=Rattus norvegicus OX=10116 GN=Furin
PE=1 SV=1
Length=793
Score = 1495 bits (3870), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 744/794 (94%), Positives = 756/794 (95%), Gaps = 1/794 (0%)
Query 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI 60
MELRPWLLWVVAA G LVLLAA+A+GQK+FTNTWAV I GGPAVA+SVARKHGF NLGQI
Sbjct 1 MELRPWLLWVVAAAGALVLLAAEARGQKIFTNTWAVHISGGPAVADSVARKHGFHNLGQI 60
Query 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
FGDYYHFWHR VTKRSLSPHRPRHSRLQR PQV+WLEQQVAK+R KRDVYQEPTDPKFPQ
Sbjct 61 FGDYYHFWHRAVTKRSLSPHRPRHSRLQRVPQVKWLEQQVAKQRAKRDVYQEPTDPKFPQ 120
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
QWYLSGVTQRDLNVK AWAQG+TG GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP
Sbjct 121 QWYLSGVTQRDLNVKEAWAQGFTGRGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
Query 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL
Sbjct 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH
Sbjct 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
Query 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC
Sbjct 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV
Sbjct 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
Query 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH 480
SHSYGYGLLDAGAMVALAQNWTTVAPQRKCII+IL EPKDIGKRLEVRKTVTACLGEPNH
Sbjct 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIEILAEPKDIGKRLEVRKTVTACLGEPNH 480
Query 481 ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
I+RLEH QARLTLSYNRRGDLAIHL+SPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD
Sbjct 481 ISRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
Query 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCE 600
EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA EGL PPESSGCKTLTSSQACVVCE
Sbjct 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTASEGLSAPPESSGCKTLTSSQACVVCE 600
Query 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL 660
EGFSLHQKSCVQ CPPGF PQVLDTHYSTENDVE IRASVC PCHASCATCQGPA TDCL
Sbjct 601 EGFSLHQKSCVQRCPPGFTPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCL 660
Query 661 SCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGL 720
SCPSHASLDPVEQTCSRQSQSSRES PQQ PP L PEVE RLRAG L SHLPEV+AGL
Sbjct 661 SCPSHASLDPVEQTCSRQSQSSRESRPQQPPPALRPEVEVEPRLRAG-LASHLPEVLAGL 719
Query 721 SCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG 780
SC I L+F VFL L SGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG
Sbjct 720 SCLIIALIFGIVFLFLHRCSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG 779
Query 781 RGERTAFIKDQSAL 794
RGERTAFIKDQSAL
Sbjct 780 RGERTAFIKDQSAL 793
>sp|P29119|FURI1_XENLA Furin-1 OS=Xenopus laevis OX=8355 GN=furin
PE=2 SV=1
Length=783
Score = 1167 bits (3020), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 553/778 (71%), Positives = 634/778 (81%), Gaps = 13/778 (2%)
Query 19 LLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLS 78
+L + GQKV+TNTWA I GG A A+ + +K+GF+N G IF D+YHF HR V KRSL+
Sbjct 17 VLVEEITGQKVYTNTWAAHISGGSAEADRLCKKYGFINHGLIFEDHYHFSHRAVMKRSLT 76
Query 79 PHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAW 138
P R R L+REPQV WLEQQVAK+R KRD+Y +PTDPKF QQWYL + DL+VK AW
Sbjct 77 PKRTRQVLLKREPQVHWLEQQVAKKRKKRDIYTDPTDPKFMQQWYLLDTNRHDLHVKEAW 136
Query 139 AQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRC 198
QG+TG GIVVSILDDGIEKNHPDL NYDP AS+DVNDQDPDPQPRYTQ+NDNRHGTRC
Sbjct 137 EQGFTGKGIVVSILDDGIEKNHPDLQANYDPAASYDVNDQDPDPQPRYTQLNDNRHGTRC 196
Query 199 AGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPED 258
AGEVAAVANNG+CGVG+AYNA IGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPED
Sbjct 197 AGEVAAVANNGICGVGIAYNANIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPED 256
Query 259 DGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSIS 318
DGKTVDGPA+LAEEAF+RGV+QGRGGLGSI+VWASGNGGREHDSCNCDGYTNSIYTLSIS
Sbjct 257 DGKTVDGPAKLAEEAFYRGVTQGRGGLGSIYVWASGNGGREHDSCNCDGYTNSIYTLSIS 316
Query 319 SATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGII 378
S TQ GNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCT+SHTGTSASAPLAAGII
Sbjct 317 STTQMGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTDSHTGTSASAPLAAGII 376
Query 379 ALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALA 438
AL LEANKNLTWRDMQHLVVQTS PA LNANDW TNGVGRKVSHSYGYGLLDAGAMVA+A
Sbjct 377 ALALEANKNLTWRDMQHLVVQTSNPAGLNANDWITNGVGRKVSHSYGYGLLDAGAMVAMA 436
Query 439 QNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRR 498
+ W TV PQRK +IDIL+EPKDIGK LEVR+ V C G N+I+ LEH QARL+LSYN R
Sbjct 437 KTWVTVGPQRKYVIDILSEPKDIGKALEVRRKVEPCAGMSNYISTLEHVQARLSLSYNCR 496
Query 499 GDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEAN 558
GDLAI+L SPMGTRS LLA RPHDYSADGFNDW+FMTTHSWDEDP+GEWVLEIEN S N
Sbjct 497 GDLAIYLTSPMGTRSCLLAPRPHDYSADGFNDWSFMTTHSWDEDPAGEWVLEIENVSNNN 556
Query 559 NYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGF 618
NYGTLT+F LVLYGTA EGL + G + + SSQ+C+VCEEG+ LHQKSC++ CP GF
Sbjct 557 NYGTLTQFVLVLYGTASEGLSRKFDGDGSRNVASSQSCIVCEEGYFLHQKSCIKSCPQGF 616
Query 619 APQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQ 678
+ + HY+ +N++E + +VC PCH SCATC+G + DCL+CP+H+ + ++ +C+ Q
Sbjct 617 TSSIQNIHYTLDNNIEPLLVNVCVPCHVSCATCKGTTINDCLTCPAHSHYNLLDYSCTHQ 676
Query 679 SQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVTVFLVLQL 738
+Q SRESP + + R S+LP +VA LSC FI++VF ++FL LQL
Sbjct 677 TQRSRESPTLKDSSH-----DYVAR------TSNLPFIVAILSCLFIIVVFGSIFLFLQL 725
Query 739 RSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDE--GRGERTAFIKDQSAL 794
RSG ++Y +D G+ISYKG+P AWQEE S+SE +E ERTAF+K QS L
Sbjct 726 RSGGVLGRKRLYMLDSGIISYKGIPSGAWQEEGFSESETEETAAHSERTAFLKQQSTL 783
>sp|Q6UW60|PCSK4_HUMAN Proprotein convertase subtilisin/kexin
type 4 OS=Homo sapiens OX=9606 GN=PCSK4 PE=1 SV=2
Length=755
Score = 773 bits (1995), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 381/654 (58%), Positives = 467/654 (71%), Gaps = 10/654 (2%)
Query 29 VFTNTWAVRIPGGPAVANSVARKHGFLNLGQIF--GDYYHFWHRGVTKRSLSPHRPRHSR 86
++ ++WAV++ G +ARK GF+NLG IF G Y+H HRGV ++SL+PH
Sbjct 33 IYVSSWAVQVSQGNREVERLARKFGFVNLGPIFPDGQYFHLRHRGVVQQSLTPHWGHRLH 92
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
L++ P+VQW +QQ +RR KR V PTDP F +QWY++ Q DL++ AW+QG +G G
Sbjct 93 LKKNPKVQWFQQQTLQRRVKRSVV-VPTDPWFSKQWYMNSEAQPDLSILQAWSQGLSGQG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
IVVS+LDDGIEK+HPDL NYDP AS+D ND DPDPQPRYT +NRHGTRCAGEVAA+A
Sbjct 152 IVVSVLDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPSKENRHGTRCAGEVAAMA 211
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
NNG CGVGVA+NARIGGVRMLDG +TD +EA+SL L P HIHIYSASWGPEDDG+TVDGP
Sbjct 212 NNGFCGVGVAFNARIGGVRMLDGTITDVIEAQSLSLQPQHIHIYSASWGPEDDGRTVDGP 271
Query 267 ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNV 326
L EAF RGV++GRGGLG++F+WASGNGG +D+CNCDGYTNSI+TLS+ S TQ G V
Sbjct 272 GILTREAFRRGVTKGRGGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTQQGRV 331
Query 327 PWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANK 386
PWYSEAC+STL TTYSSG + QIVTTDL CT+ HTGTSASAPLAAG+IAL LEAN
Sbjct 332 PWYSEACASTLTTTYSSGVATDPQIVTTDLHHGCTDQHTGTSASAPLAAGMIALALEANP 391
Query 387 NLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAP 446
LTWRDMQHLVV+ SKPAHL A DW TNGVGR+VSH YGYGLLDAG +V A+ W P
Sbjct 392 FLTWRDMQHLVVRASKPAHLQAEDWRTNGVGRQVSHHYGYGLLDAGLLVDTARTWLPTQP 451
Query 447 QRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLV 506
QRKC + + + P I + +R+ V+AC G N I LEH QA+LTLSY+RRGDL I L
Sbjct 452 QRKCAVRVQSRPTPILPLIYIRENVSACAGLHNSIRSLEHVQAQLTLSYSRRGDLEISLT 511
Query 507 SPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKF 566
SPMGTRSTL+A RP D S +G+N+W FM+TH WDE+P G W L +EN N GTL ++
Sbjct 512 SPMGTRSTLVAIRPLDVSTEGYNNWVFMSTHFWDENPQGVWTLGLENKGYYFNTGTLYRY 571
Query 567 TLVLYGTAPE--GLPVPPE--SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQV 622
TL+LYGTA + P P+ SS C + C C+ + + C+ +CPP F
Sbjct 572 TLLLYGTAEDMTARPTGPQVTSSACVQRDTEGLCQACDGPAYILGQLCLAYCPPRFFNHT 631
Query 623 -LDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTC 675
L T +R VC+ CHASC TC+G + DC SCP ++LD + +C
Sbjct 632 RLVTAGPGHTAAPALR--VCSSCHASCYTCRGGSPRDCTSCPPSSTLDQQQGSC 683
>sp|Q78EH2|PCSK4_RAT Proprotein convertase subtilisin/kexin type
4 OS=Rattus norvegicus OX=10116 GN=Pcsk4 PE=2 SV=1
Length=678
Score = 716 bits (1849), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 349/579 (60%), Positives = 426/579 (74%), Gaps = 7/579 (1%)
Query 29 VFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGD--YYHFWHRGVTKRSLSPHRPRHSR 86
++ ++WAVR+ G A +ARK GF+NLGQIF D Y+H HRGV ++SL+PH R
Sbjct 30 IYVSSWAVRVTKGYQEAERLARKFGFVNLGQIFPDDQYFHLRHRGVAQQSLTPHWGHRLR 89
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
L++EP+V+W EQQ +RR KR + PTDP F +QWY++ ++DLN+ W QG TG G
Sbjct 90 LKKEPKVRWFEQQTLRRRVKRSLV-VPTDPWFSKQWYMNKEIEQDLNILKVWNQGLTGRG 148
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+VVSILDDGIEK+HPDL NYDP AS+D ND DPDPQPRYT ++NRHGTRCAGEV+A A
Sbjct 149 VVVSILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATA 208
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
NNG CG GVA+NARIGGVRMLDG +TD VEA+SL L P HIHIYSASWGPEDDG+TVDGP
Sbjct 209 NNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGP 268
Query 267 ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNV 326
L +EAF RGV++GR GLG++F+WASGNGG +D+CNCDGYTNSI+TLS+ S T+ G V
Sbjct 269 GLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRV 328
Query 327 PWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANK 386
PWYSEAC+ST TT+SSG + QIVTTDL +CT+ HTGTSASAPLAAG+IAL LEAN
Sbjct 329 PWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANP 388
Query 387 NLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAP 446
LTWRD+QHLVV+ S+PA L A DW NGVGR+VSH YGYGLLDAG +V LA+ W P
Sbjct 389 LLTWRDLQHLVVRASRPAQLQAEDWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPTKP 448
Query 447 QRKCIIDILTEPKDIGKRLEVRKTVTACL-GEPNHITR-LEHAQARLTLSYNRRGDLAIH 504
Q+KC I ++ P I R+ V K VT C G + R LEH Q +L+LSY+RRGDL I
Sbjct 449 QKKCTIRVVHTPTPILPRMLVPKNVTVCCDGSRRRLIRSLEHVQVQLSLSYSRRGDLEIF 508
Query 505 LVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLT 564
L SPMGTRSTL+A RP D S G+N+W FM+TH WDEDP G W L +EN N GTL
Sbjct 509 LTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLENKGYYYNTGTLY 568
Query 565 KFTLVLYGTAPE--GLPVPPESSGCKTLTSSQACVVCEE 601
TL+LYGTA + P P+ S C ++ C++ +
Sbjct 569 YCTLLLYGTAEDMTARPQTPQESHCPLSIVAELCLISSK 607
>sp|P29121|PCSK4_MOUSE Proprotein convertase subtilisin/kexin
type 4 OS=Mus musculus OX=10090 GN=Pcsk4 PE=2 SV=1
Length=655
Score = 697 bits (1800), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 334/529 (63%), Positives = 404/529 (76%), Gaps = 5/529 (1%)
Query 29 VFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGD--YYHFWHRGVTKRSLSPHRPRHSR 86
++ ++WAVR+ G A +ARK GF+NLGQIF D Y+H HRGV ++SL+PH R
Sbjct 30 IYVSSWAVRVTKGYQEAERLARKFGFVNLGQIFPDDQYFHLRHRGVAQQSLTPHWGHRLR 89
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
L+++P+V+W EQQ +RR KR + PTDP F +QWY++ Q+DLN+ AW QG TG G
Sbjct 90 LKKDPKVRWFEQQTLRRRVKRSLV-VPTDPWFSKQWYMNKEIQQDLNILKAWNQGLTGRG 148
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+V+SILDDGIEK+HPDL NYDP AS+D ND DPDPQPRYT ++NRHGTRCAGEV+A A
Sbjct 149 VVISILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSATA 208
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
NNG CG GVA+NARIGGVRMLDG +TD VEA+SL L P HIHIYSASWGPEDDG+TVDGP
Sbjct 209 NNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDGP 268
Query 267 ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNV 326
L +EAF RGV++GR GLG++F+WASGNGG +D+CNCDGYTNSI+TLS+ S T+ G V
Sbjct 269 GLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGRV 328
Query 327 PWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANK 386
PWYSEAC+ST TT+SSG + QIVTTDL +CT+ HTGTSASAPLAAG+IAL LEAN
Sbjct 329 PWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEANP 388
Query 387 NLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAP 446
LTWRD+QHLVV+ S+PA L A DW NGVGR+VSH YGYGLLDAG +V LA+ W P
Sbjct 389 LLTWRDLQHLVVRASRPAQLQAEDWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPTKP 448
Query 447 QRKCIIDILTEPKDIGKRLEVRKTVTACL-GEPNHITR-LEHAQARLTLSYNRRGDLAIH 504
Q+KC I ++ P I R+ V K VTAC G + R LEH Q +L+LSY+RRGDL I
Sbjct 449 QKKCAIRVVHTPTPILPRMLVPKNVTACSDGSRRRLIRSLEHVQVQLSLSYSRRGDLEIF 508
Query 505 LVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIEN 553
L SPMGTRSTL+A RP D S G+N+W FM+TH WDEDP G W L +EN
Sbjct 509 LTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLEN 557
>sp|Q04592|PCSK5_MOUSE Proprotein convertase subtilisin/kexin
type 5 OS=Mus musculus OX=10090 GN=Pcsk5 PE=1 SV=3
Length=1877
Score = 669 bits (1725), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 365/727 (50%), Positives = 453/727 (62%), Gaps = 73/727 (10%)
Query 7 LLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--FGDY 64
LL V+A +L +V+TN WAV+I GG A A+ +A K+GF+N+GQI DY
Sbjct 17 LLCVLALLAGCLLPVCRT---RVYTNHWAVKIAGGFAEADRIASKYGFINVGQIGALKDY 73
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDV---YQEPT---DPKF 118
YHF+H KRS+ R HS + EP+V+W++QQV K+RTKRD + + T DPK+
Sbjct 74 YHFYHSRTIKRSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDLSHAQSTYFNDPKW 133
Query 119 PQQWYL-----SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
P WY+ + Q D+N++ AW +GYTG IVV+ILDDGIE+ HPDL NYD AS
Sbjct 134 PSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASC 193
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTD 233
DVN D DP PRY N+N+HGTRCAGEVAA ANN C VG+A+NA+IGGVRMLDG+VTD
Sbjct 194 DVNGNDLDPMPRYDASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDGDVTD 253
Query 234 AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWAS 293
VEA+S+ NP H+HIYSASWGP+DDGKTVDGPA L +AF GV GR GLGS+FVWAS
Sbjct 254 MVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWAS 313
Query 294 GNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVT 353
GNGGR D C+CDGYTNSIYT+SISS + G PWY E CSSTLATTYSSG +K+I+T
Sbjct 314 GNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIIT 373
Query 354 TDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWAT 413
TDLRQ+CT++HTGTSASAP+AAGIIAL LEAN LTWRD+QH++V+TS+ HLNANDW T
Sbjct 374 TDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKT 433
Query 414 NGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTA 473
N G KVSH YG+GL+DA AMV A+ WTTV Q C+ + K I VR A
Sbjct 434 NAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIRPNSAVRSIYKA 493
Query 474 --CLGEPN-HITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFND 530
C PN H+ LEH R+T+++ RRGDLAI+L SP GTRS LLA R D+S +GF +
Sbjct 494 SGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKN 553
Query 531 WAFMTTHSWDEDPSGEWVLEIENT-SEANNY---GTLTKFTLVLYGTAPEGL-------- 578
W FMT H W E +G+WVLE+ +T S+ N+ G L +++LVLYGT+ +
Sbjct 554 WEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPK 613
Query 579 -----------------------PVPPESS--GCKTLTSSQACVVCEEGFSLHQKS--CV 611
P PE S GC + L + CV
Sbjct 614 VERFRYSRVEDPTDDYGAEDYAGPCDPECSEVGCDGPGPDHCSDCLHYYYKLKNNTRICV 673
Query 612 QHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPV 671
CPPG HY + R CAP +C +C G CLSC L+
Sbjct 674 SSCPPG--------HYHADKK----RCRKCAP---NCESCFGSHGNQCLSCKYGYFLNEE 718
Query 672 EQTCSRQ 678
+C Q
Sbjct 719 TSSCVTQ 725
Score = 43.5 bits (101), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 36/101 (36%), Positives = 37/101 (37%), Gaps = 18/101 (18%)
Query 566 FTLVLYGTAPEG-LPVPPESSGCKTLTSS---QACVVCEEGFSLHQKSCVQHCPPGFAPQ 621
F Y PE V E C T S C CEEGF L SCVQ C PGF
Sbjct 1065 FERHCYKACPEKTFGVKWECRACGTNCGSCDQHECYWCEEGFFLSGGSCVQDCGPGF--- 1121
Query 622 VLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSC 662
D E C PCH +C C G C SC
Sbjct 1122 --------HGDQEL---GECKPCHRACENCTGSGYNQCSSC 1151
Score = 42.4 bits (98), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 32/95 (34%), Positives = 44/95 (46%), Gaps = 12/95 (13%)
Query 577 GLPVPPESSGCKTLTSSQA--CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
G P C T + + A C+ C EG+ + + CVQ C + LD +S+E +
Sbjct 781 GHDCQPCHRFCATCSGAGADGCINCTEGYVMEEGRCVQSCSVSY---YLD--HSSEGGYK 835
Query 635 TIRASVCAPCHASCATCQGPALTDCLSCPSHASLD 669
+ C C SC TC GP +C SCPS LD
Sbjct 836 S-----CKRCDNSCLTCNGPGFKNCSSCPSGYLLD 865
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 25/71 (35%), Positives = 31/71 (44%), Gaps = 14/71 (20%)
Query 592 SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATC 651
S C C L +CV+ CP G Y T+ D + C CH+SC TC
Sbjct 1508 SEDQCYTCPRETFLLNTTCVKECPEG---------YHTDKDSQQ-----CVLCHSSCRTC 1553
Query 652 QGPALTDCLSC 662
+GP CLSC
Sbjct 1554 EGPHSMQCLSC 1564
Score = 36.6 bits (83), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 21/76 (28%), Positives = 27/76 (36%), Gaps = 16/76 (21%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C+ + C C F L+ C + CP F P + C PCH
Sbjct 1357 CQDCIHEKTCKECMPDFFLYNDMCHRSCPKSFYPDMRQ----------------CVPCHK 1400
Query 647 SCATCQGPALTDCLSC 662
+C C GP DC C
Sbjct 1401 NCLECNGPKEDDCKVC 1416
Score = 36.6 bits (83), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 29/98 (30%), Positives = 42/98 (43%), Gaps = 18/98 (18%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAP-QVLDTHYSTENDVETIRASV 640
PES C +S+ C+ C EGF++ C AP + Y E +
Sbjct 1449 PES--CLICSSAWTCLACREGFTVVHDVCT-------APKECAAVEYWDEG------SHR 1493
Query 641 CAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQ 678
C PCH C+ C GP+ C +CP L + TC ++
Sbjct 1494 CQPCHKKCSRCSGPSEDQCYTCPRETFL--LNTTCVKE 1529
Score = 34.3 bits (77), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 16/29 (55%), Positives = 17/29 (59%), Gaps = 0/29 (0%)
Query 641 CAPCHASCATCQGPALTDCLSCPSHASLD 669
C C ASCA C GP DC+SCP LD
Sbjct 887 CQTCEASCAKCWGPTQEDCISCPVTRVLD 915
>sp|Q63415|PCSK6_RAT Proprotein convertase subtilisin/kexin type
6 OS=Rattus norvegicus OX=10116 GN=Pcsk6 PE=1 SV=1
Length=937
Score = 668 bits (1724), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 358/723 (50%), Positives = 449/723 (62%), Gaps = 80/723 (11%)
Query 4 RPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--F 61
RPW ++ A + +A + V+TN WAV++ GGP A+ VA HG+LNLGQI
Sbjct 29 RPWRWLLLLALPAVC--SALPPPRPVYTNHWAVQVLGGPGAADRVAAAHGYLNLGQIGNL 86
Query 62 GDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP---TDPKF 118
DYYHF+H KRS R H+ L+ +PQV+WL+QQ KRR KR + DP +
Sbjct 87 DDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQARSDSLYFNDPIW 146
Query 119 PQQWYL-----SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
WY+ + + ++NV+AAW +GYTG +VV+ILDDGIE+NHPDLA NYD AS+
Sbjct 147 SNMWYMHCADKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASY 206
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTD 233
DVN D DP PRY N+N+HGTRCAGEVAA ANN C VG+AYNA+IGG+RMLDG+VTD
Sbjct 207 DVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTD 266
Query 234 AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWAS 293
VEA+SLG+ PN+I IYSASWGP+DDGKTVDGP RLA++AF G+ +GR GLGSIFVWAS
Sbjct 267 VVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWAS 326
Query 294 GNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVT 353
GNGGRE D C+CDGYTNSIYT+S+SS T+ G+ PWY E C+STLATTYSSG E++IVT
Sbjct 327 GNGGREGDHCSCDGYTNSIYTISVSSTTENGHKPWYLEECASTLATTYSSGAFYERKIVT 386
Query 354 TDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWAT 413
TDLRQ+CT+ HTGTS SAP+ AGIIAL LEAN LTWRD+QHL+V+TS+PAHL A+DW
Sbjct 387 TDLRQRCTDGHTGTSVSAPMVAGIIALALEANNQLTWRDVQHLLVKTSRPAHLKASDWKV 446
Query 414 NGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKT--V 471
NG G KVSH YG+GL+DA A+V A+ WT V Q C+ P+ I +R T
Sbjct 447 NGAGHKVSHLYGFGLVDAEALVLEARKWTAVPSQHMCVATADKRPRSIPVVQVLRTTALT 506
Query 472 TACLGEPNH-ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFND 530
AC + + LEH R+++S+ RRGDL IHL+SP GT+S LLA R D+S +GF +
Sbjct 507 NACADHSDQRVVYLEHVVVRISISHPRRGDLQIHLISPSGTKSQLLAKRLLDFSNEGFTN 566
Query 531 WAFMTTHSWDEDPSGEWVLEIENT-SEANN---YGTLTKFTLVLYGTA------------ 574
W FMT H W E GEW LE+++ S+ N G L +++L+LYGTA
Sbjct 567 WEFMTVHCWGEKAEGEWTLEVQDIPSQVRNPEKQGKLKEWSLILYGTAEHPYRTFSSHQS 626
Query 575 ---------PEGLPVPPE------------------------SSGCKTLTSSQA--CVVC 599
PE P+ E GC ++ Q CV
Sbjct 627 RSRMLELSVPEQEPLKAEGPPPQAETPEEEEEYTGVCHPECGDKGCDGPSADQCLNCVHF 686
Query 600 EEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDC 659
G S + CV CP G+ A C CH C TC G + T C
Sbjct 687 SLGNSKTNRKCVSECPLGYFGDTA--------------ARRCRRCHKGCETCTGRSPTQC 732
Query 660 LSC 662
LSC
Sbjct 733 LSC 735
Score = 51.2 bits (121), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 32/93 (34%), Positives = 43/93 (46%), Gaps = 14/93 (15%)
Query 570 LYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
LY + L + S K + + VC+EGFSL + SC+ C PG T
Sbjct 756 LYADESQRLCLRCHPSCQKCVDEPEKSTVCKEGFSLARGSCIPDCEPG-----------T 804
Query 630 ENDVETIRASVCAPCHASCATCQGPALTDCLSC 662
D E IR C CH +C TC GP+ +C+ C
Sbjct 805 YFDSELIR---CGECHHTCRTCVGPSREECIHC 834
>sp|Q92824|PCSK5_HUMAN Proprotein convertase subtilisin/kexin
type 5 OS=Homo sapiens OX=9606 GN=PCSK5 PE=1 SV=4
Length=1860
Score = 668 bits (1723), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 330/567 (58%), Positives = 405/567 (71%), Gaps = 20/567 (4%)
Query 28 KVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--FGDYYHFWHRGVTKRSLSPHRPRHS 85
+V+TN WAV+I GG AN +A K+GF+N+GQI DYYHF+H KRS+ R HS
Sbjct 33 RVYTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRTIKRSVISSRGTHS 92
Query 86 RLQREPQVQWLEQQVAKRRTKRDV------YQEPTDPKFPQQWYL-----SGVTQRDLNV 134
+ EP+V+W++QQV K+RTKRD DPK+P WY+ + Q D+N+
Sbjct 93 FISMEPKVEWIQQQVVKKRTKRDYDFSRAQSTYFNDPKWPSMWYMHCSDNTHPCQSDMNI 152
Query 135 KAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRH 194
+ AW +GYTG IVV+ILDDGIE+ HPDL NYD AS DVN D DP PRY N+N+H
Sbjct 153 EGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLDPMPRYDASNENKH 212
Query 195 GTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASW 254
GTRCAGEVAA ANN C VG+A+NA+IGGVRMLDG+VTD VEA+S+ NP H+HIYSASW
Sbjct 213 GTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLDGDVTDMVEAKSVSFNPQHVHIYSASW 272
Query 255 GPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYT 314
GP+DDGKTVDGPA L +AF GV GR GLGS+FVWASGNGGR D C+CDGYTNSIYT
Sbjct 273 GPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKDHCSCDGYTNSIYT 332
Query 315 LSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLA 374
+SISS + G PWY E CSSTLATTYSSG +K+I+TTDLRQ+CT++HTGTSASAP+A
Sbjct 333 ISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCTDNHTGTSASAPMA 392
Query 375 AGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAM 434
AGIIAL LEAN LTWRD+QH++V+TS+ HLNANDW TN G KVSH YG+GL+DA AM
Sbjct 393 AGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVSHLYGFGLMDAEAM 452
Query 435 VALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTA--CLGEPN-HITRLEHAQARL 491
V A+ WTTV Q C+ + K I VR A C PN H+ LEH R+
Sbjct 453 VMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPNRHVNYLEHVVVRI 512
Query 492 TLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEI 551
T+++ RRGDLAI+L SP GTRS LLA R D+S +GF +W FMT H W E +G+WVLE+
Sbjct 513 TITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEV 572
Query 552 ENT-SEANNY---GTLTKFTLVLYGTA 574
+T S+ N+ G L +++LVLYGT+
Sbjct 573 YDTPSQLRNFKTPGKLKEWSLVLYGTS 599
Score = 43.9 bits (102), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 36/104 (35%), Positives = 42/104 (40%), Gaps = 22/104 (21%)
Query 565 KFTLVLYGTAPEGLPVPPESSGCKTLTSS------QACVVCEEGFSLHQKSCVQHCPPGF 618
+F Y T PE E CK S+ C CEEGF L SCV+ C PGF
Sbjct 1062 RFDHHCYKTCPE--KTYSEEVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGF 1119
Query 619 APQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSC 662
Y + E C CH +C TC GP +C SC
Sbjct 1120 --------YGDQEMGE------CESCHRACETCTGPGHDECSSC 1149
Score = 43.9 bits (102), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 10/77 (13%)
Query 593 SQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQ 652
+ C+ C EG+ + CVQ C + D +S+EN ++ C C SC TC
Sbjct 797 ADGCINCTEGYFMEDGRCVQSCSISY---YFD--HSSENGYKS-----CKKCDISCLTCN 846
Query 653 GPALTDCLSCPSHASLD 669
GP +C SCPS LD
Sbjct 847 GPGFKNCTSCPSGYLLD 863
Score = 37.7 bits (86), Expect = 0.55, Method: Compositional matrix adjust.
Identities = 24/76 (32%), Positives = 28/76 (37%), Gaps = 16/76 (21%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C+ + C C F LH C Q CP GF D+ + C PCH
Sbjct 1330 CQDCIHEKTCKECTPEFFLHDDMCHQSCPRGF---YADSRH-------------CVPCHK 1373
Query 647 SCATCQGPALTDCLSC 662
C C GP DC C
Sbjct 1374 DCLECSGPKADDCELC 1389
Score = 36.6 bits (83), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 26/79 (33%), Positives = 29/79 (37%), Gaps = 16/79 (20%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
S CKT T C C +G SL C C G Y D C P
Sbjct 741 SENCKTCTEFHNCTECRDGLSLQGSRCSVSCEDG--------RYFNGQD--------CQP 784
Query 644 CHASCATCQGPALTDCLSC 662
CH CATC G C++C
Sbjct 785 CHRFCATCAGAGADGCINC 803
Score = 35.8 bits (81), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 27/85 (32%), Positives = 40/85 (47%), Gaps = 17/85 (20%)
Query 587 CKTLTSSQACVVCEEGFSLHQK-SCV--QHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
C T +SS C C++G ++ + SC+ + C P + Y E+ A C P
Sbjct 1425 CLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSP--------SEYWDED------APGCKP 1470
Query 644 CHASCATCQGPALTDCLSCPSHASL 668
CH C C GPA C +CP ++ L
Sbjct 1471 CHVKCFHCMGPAEDQCQTCPMNSLL 1495
Score = 34.7 bits (78), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 40/128 (31%), Positives = 50/128 (39%), Gaps = 36/128 (28%)
Query 574 APEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAP-------QVLDTH 626
PEG +S+ C SS C CE H + C C PG+ Q + +
Sbjct 1504 CPEGYYADEDSNRCAHCHSS--CRTCE---GRHSRQC-HSCRPGWFQLGKECLLQCREGY 1557
Query 627 YSTENDVETIRASVCAPCHASCATCQGPALTDCL-----------------SCPSHASLD 669
Y+ D T R C C+ SC CQGP TDCL SCP H ++
Sbjct 1558 YA---DNSTGR---CERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVE 1611
Query 670 PVEQTCSR 677
QTC R
Sbjct 1612 QSTQTCER 1619
Score = 33.9 bits (76), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 14/23 (61%), Positives = 15/23 (65%), Gaps = 0/23 (0%)
Query 641 CAPCHASCATCQGPALTDCLSCP 663
C C ASCA CQGP DC +CP
Sbjct 885 CQTCEASCAKCQGPTQEDCTTCP 907
>sp|P41413|PCSK5_RAT Proprotein convertase subtilisin/kexin type
5 OS=Rattus norvegicus OX=10116 GN=Pcsk5 PE=2 SV=3
Length=1809
Score = 667 bits (1721), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 365/731 (50%), Positives = 451/731 (62%), Gaps = 81/731 (11%)
Query 7 LLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--FGDY 64
LL V+A +L +V+TN WAV+I GG A A+ +A K+GF+N+GQI DY
Sbjct 17 LLCVLALLAGCLLPVCRT---RVYTNHWAVKIAGGFAEADRIASKYGFINVGQIGALKDY 73
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP------TDPKF 118
YHF+H KRS+ R HS + EP+V+W++QQV K+RTKRD DPK+
Sbjct 74 YHFYHSRTIKRSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDLSRAQSTYFNDPKW 133
Query 119 PQQWYL-----SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
P WY+ + Q D+N++ AW +GYTG IVV+ILDDGIE+ HPDL NYD AS
Sbjct 134 PSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASC 193
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTD 233
DVN D DP PRY N+N+HGTRCAGEVAA ANN C VG+A+NA+IGGVRMLDG+VTD
Sbjct 194 DVNGNDLDPMPRYDASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDGDVTD 253
Query 234 AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWAS 293
VEA+S+ NP H+HIYSASWGP+DDGKTVDGPA L +AF GV GR GLGS+FVWAS
Sbjct 254 MVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWAS 313
Query 294 GNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVT 353
GNGGR D C+CDGYTNSIYT+SISS + G PWY E CSSTLATTYSSG +K+I+T
Sbjct 314 GNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIIT 373
Query 354 TDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWAT 413
TDLRQ+CT++HTGTSASAP+AAGIIAL LEAN LTWRD+QH++V+TS+ HLNANDW T
Sbjct 374 TDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKT 433
Query 414 NGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTA 473
N G KVSH YG+GL+DA AMV A+ WTTV Q C+ + K I VR A
Sbjct 434 NAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIRPNSAVRSIYKA 493
Query 474 --CLGEPN-HITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFND 530
C PN H+ LEH R+T+++ RRGDLAI+L SP GTRS LLA R D+S +GF +
Sbjct 494 SGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKN 553
Query 531 WAFMTTHSWDEDPSGEWVLEIENT-SEANNY---GTLTKFTLVLYGTAPEGL-------- 578
W FMT H W E +G+WVLE+ +T S+ N+ G L +++LVLYGT+ +
Sbjct 554 WEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPK 613
Query 579 -----------------------PVPPESS--GCKTLTSSQACVVCEEGFSLHQK----- 608
P PE S GC C + H K
Sbjct 614 VERFRYSRVEDPTDDYGAEDYAGPCDPECSEVGCDGPGPDH----CTDCLHYHYKLKNNT 669
Query 609 -SCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHAS 667
CV CPPG H+ + R CAP +C +C G CLSC
Sbjct 670 RICVSSCPPG--------HFHADKK----RCRKCAP---NCESCFGSHADQCLSCKYGYF 714
Query 668 LDPVEQTCSRQ 678
L+ +C Q
Sbjct 715 LNEETSSCVAQ 725
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 29/68 (43%), Positives = 31/68 (46%), Gaps = 14/68 (21%)
Query 596 CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPA 655
C CEEGF L SCVQ C PGF Y + E C PCH +C TC G
Sbjct 1030 CYWCEEGFFLSSGSCVQDCDPGF--------YGDQELGE------CKPCHRACETCTGLG 1075
Query 656 LTDCLSCP 663
C SCP
Sbjct 1076 YNQCSSCP 1083
Score = 42.4 bits (98), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 26/71 (37%), Positives = 32/71 (45%), Gaps = 14/71 (20%)
Query 592 SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATC 651
S C C L +CV+ CP G Y T+ D + C PCH+SC TC
Sbjct 1439 SENQCYTCPRETFLLNTTCVKECPEG---------YHTDKD-----SHQCVPCHSSCRTC 1484
Query 652 QGPALTDCLSC 662
+GP CLSC
Sbjct 1485 EGPHSMQCLSC 1495
Score = 41.6 bits (96), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 10/77 (13%)
Query 593 SQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQ 652
+ C+ C EG+ + + CVQ C + LD +S E ++ C C SC TC
Sbjct 799 ADGCINCTEGYVMEEGRCVQSCSVSY---YLD--HSLEGGYKS-----CKRCDNSCLTCN 848
Query 653 GPALTDCLSCPSHASLD 669
GP +C SCPS LD
Sbjct 849 GPGFKNCSSCPSGYLLD 865
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 28/97 (29%), Positives = 43/97 (44%), Gaps = 16/97 (16%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVC 641
PES C +S+ C+ C EGF++ Q C AP+ + + + C
Sbjct 1380 PES--CLICSSAWTCLTCREGFTVVQDVCT-------APKEC-----AAIEYWDVGSHRC 1425
Query 642 APCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQ 678
PCH C+ C GP+ C +CP L + TC ++
Sbjct 1426 QPCHRKCSRCSGPSENQCYTCPRETFL--LNTTCVKE 1460
Score = 37.0 bits (84), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 21/76 (28%), Positives = 27/76 (36%), Gaps = 16/76 (21%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C+ + C C F L+ C CP F P + C PCH
Sbjct 1288 CQDCIHEKTCKECMPDFFLYNDMCHHSCPKNFYPDMRQ----------------CVPCHK 1331
Query 647 SCATCQGPALTDCLSC 662
+C C GP DC +C
Sbjct 1332 NCLGCNGPKEDDCKAC 1347
Score = 36.6 bits (83), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 34/126 (27%), Positives = 44/126 (35%), Gaps = 33/126 (26%)
Query 571 YGTAPEGLPVPPESSGCKTLTS--SQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYS 628
Y T + P S C+T S C+ C G+ K C+ C G+ +
Sbjct 1465 YHTDKDSHQCVPCHSSCRTCEGPHSMQCLSCRPGWFQLGKECLLQCRDGYYGEST----- 1519
Query 629 TENDVETIRASVCAPCHASCATCQGPALTDC-----------------LSCPSHASLDPV 671
+ C C SC TC+GP TDC L+CP H D
Sbjct 1520 ---------SGRCEKCDKSCKTCRGPQPTDCQSCDTFFFLLRSKGQCHLACPEHYYADQH 1570
Query 672 EQTCSR 677
QTC R
Sbjct 1571 AQTCER 1576
Score = 36.2 bits (82), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 26/79 (33%), Positives = 29/79 (37%), Gaps = 16/79 (20%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
S CKT T C C+ G SL C C G Q H C P
Sbjct 743 SENCKTCTGFHNCTECKGGLSLQGSRCSVTCEDG---QFFSGH-------------DCQP 786
Query 644 CHASCATCQGPALTDCLSC 662
CH CATC G C++C
Sbjct 787 CHRFCATCAGAGADGCINC 805
>sp|P29122|PCSK6_HUMAN Proprotein convertase subtilisin/kexin
type 6 OS=Homo sapiens OX=9606 GN=PCSK6 PE=1 SV=1
Length=969
Score = 659 bits (1700), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 357/699 (51%), Positives = 442/699 (63%), Gaps = 65/699 (9%)
Query 29 VFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--FGDYYHFWHRGVTKRSLSPHRPRHSR 86
V+TN WAV++ GGPA A+ VA HG+LNLGQI DYYHF+H KRS R H+
Sbjct 69 VYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTF 128
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEP-----TDPKFPQQWYL-----SGVTQRDLNVKA 136
L+ +PQV+WL+QQ KRR KR V +P DP + WYL + + ++NV+A
Sbjct 129 LRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRCRSEMNVQA 188
Query 137 AWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGT 196
AW +GYTG +VV+ILDDGIE+NHPDLA NYD AS+DVN D DP PRY N+N+HGT
Sbjct 189 AWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDASNENKHGT 248
Query 197 RCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGP 256
RCAGEVAA ANN C VG+AYNA+IGG+RMLDG+VTD VEA+SLG+ PN+I IYSASWGP
Sbjct 249 RCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYIDIYSASWGP 308
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
+DDGKTVDGP RLA++AF G+ +GR GLGSIFVWASGNGGRE D C+CDGYTNSIYT+S
Sbjct 309 DDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGYTNSIYTIS 368
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAG 376
+SSAT+ G PWY E C+STLATTYSSG E++IVTTDLRQ+CT+ HTGTS SAP+ AG
Sbjct 369 VSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTSVSAPMVAG 428
Query 377 IIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
IIAL LEAN LTWRD+QHL+V+TS+PAHL A+DW NG G KVSH YG+GL+DA A+V
Sbjct 429 IIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGLVDAEALVV 488
Query 437 LAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKT--VTACLGEPNH-ITRLEHAQARLTL 493
A+ WT V Q C+ P+ I +R T +AC + + LEH R ++
Sbjct 489 EAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLEHVVVRTSI 548
Query 494 SYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIEN 553
S+ RRGDL I+LVSP GT+S LLA R D S +GF +W FMT H W E G+W LEI++
Sbjct 549 SHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEGQWTLEIQD 608
Query 554 T-SEANN---YGTLTKFTLVLYGT---------------------APEGLPVP------- 581
S+ N G L +++L+LYGT APE P
Sbjct 609 LPSQVRNPEKQGKLKEWSLILYGTAEHPYHTFSAHQSRSRMLELSAPELEPPKAALSPSQ 668
Query 582 ---PESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRA 638
PE T S+ + H + + C A Q L+ + + V+T R
Sbjct 669 VEVPEDEEDYTAQSTPGSANILQTSVCHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRK 728
Query 639 SV---------------CAPCHASCATCQGPALTDCLSC 662
V C CH C TC A T CLSC
Sbjct 729 CVSVCPLGYFGDTAARRCRRCHKGCETCSSRAATQCLSC 767
Score = 54.7 bits (130), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 29/75 (39%), Positives = 37/75 (49%), Gaps = 14/75 (19%)
Query 588 KTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHAS 647
K + + C VC+EGFSL + SC+ C PG T D E IR C CH +
Sbjct 806 KCVDEPEKCTVCKEGFSLARGSCIPDCEPG-----------TYFDSELIR---CGECHHT 851
Query 648 CATCQGPALTDCLSC 662
C TC GP +C+ C
Sbjct 852 CGTCVGPGREECIHC 866
Score = 36.6 bits (83), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 25/70 (36%), Positives = 32/70 (46%), Gaps = 18/70 (26%)
Query 586 GCKTLTSSQA--CVVCEEGFSLHQK--SCVQHCPPGFAPQVLDTHYSTENDVETIRASVC 641
GC+T +S A C+ C GF HQ+ +CV CP GF Y+ E+ C
Sbjct 752 GCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGF--------YADESQKN------C 797
Query 642 APCHASCATC 651
CH SC C
Sbjct 798 LKCHPSCKKC 807
>sp|P26016|FUR11_DROME Furin-like protease 1, isoforms 1/1-X/2
OS=Drosophila melanogaster OX=7227 GN=Fur1 PE=2 SV=2
Length=1269
Score = 647 bits (1668), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 335/609 (55%), Positives = 412/609 (68%), Gaps = 26/609 (4%)
Query 30 FTNTWAVRIPGGP-AVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQ 88
+T+TWAV IP G +A++VA+ HGF+NLG+IF D+YHF H V+KRSLSP +RL
Sbjct 231 YTHTWAVHIPNGDNGMADAVAKDHGFVNLGKIFDDHYHFAHHKVSKRSLSPATHHQTRLD 290
Query 89 REPQVQWLEQQVAKRRTKRD-VYQEPT----------------DPKFPQQWYLSGVTQRD 131
+ +V W +QQ AK R+KRD + P+ D K+PQ WYL+ D
Sbjct 291 DDDRVHWAKQQRAKSRSKRDFIRMRPSRTSSRAMSMVDAMSFNDSKWPQMWYLNRGGGLD 350
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND 191
+NV AW G TG G+VV+ILDDG+E +HPD+ NYDP AS+DVN D DP P Y +
Sbjct 351 MNVIPAWKMGITGKGVVVTILDDGLESDHPDIQDNYDPKASYDVNSHDDDPMPHYDMTDS 410
Query 192 NRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS 251
NRHGTRCAGEVAA ANN C VG+AY A +GGVRMLDG+VTDAVEARSL LNP HI IYS
Sbjct 411 NRHGTRCAGEVAATANNSFCAVGIAYGASVGGVRMLDGDVTDAVEARSLSLNPQHIDIYS 470
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
ASWGP+DDGKTVDGP LA AF G ++GRGG GSIF+WASGNGGRE D+CNCDGYTNS
Sbjct 471 ASWGPDDDGKTVDGPGELASRAFIEGTTKGRGGKGSIFIWASGNGGREQDNCNCDGYTNS 530
Query 312 IYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASA 371
I+TLSISSAT+ G+VPWYSE CSSTLATTYSSG Q EKQ+VTTDL CT SHTGTSASA
Sbjct 531 IWTLSISSATEEGHVPWYSEKCSSTLATTYSSGGQGEKQVVTTDLHHSCTVSHTGTSASA 590
Query 372 PLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDA 431
PLAAGI AL L++N+NLTWRD+QH+VV+T+KPA+L W+ NGVGR+VSHS+GYGL+DA
Sbjct 591 PLAAGIAALVLQSNQNLTWRDLQHIVVRTAKPANLKDPSWSRNGVGRRVSHSFGYGLMDA 650
Query 432 GAMVALAQNWTTVAPQRKCIIDILTEPKDIGKR--LEVRKTVTACLGEPNHITRLEHAQA 489
MV +A+NW V Q++C I+ K I R + ++ TV C + LEH QA
Sbjct 651 AEMVRVARNWKAVPEQQRCEINAPHVDKVIPPRTHITLQLTVNHCRS----VNYLEHVQA 706
Query 490 RLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVL 549
++TL+ RRGD+ + L SP T TLL R HD S GFN W FM+ H+W E P G W L
Sbjct 707 KITLTSQRRGDIQLFLRSPANTSVTLLTPRIHDNSRSGFNQWPFMSVHTWGESPQGNWQL 766
Query 550 EIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKS 609
EI N + L +++L+ YGT P P S + + + +LHQ
Sbjct 767 EIHNEGRYMGHALLREWSLIFYGTTQSIGPNDPISVPKPSGSEATTPNSSSTTSNLHQAY 826
Query 610 CVQH--CPP 616
Q+ PP
Sbjct 827 SPQYPRIPP 835
>sp|O17798|FKPC1_CAEEL Furin-like protease kpc-1 OS=Caenorhabditis
elegans OX=6239 GN=kpc-1 PE=1 SV=3
Length=692
Score = 646 bits (1666), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 334/595 (56%), Positives = 413/595 (69%), Gaps = 48/595 (8%)
Query 27 QKVFTNTWAVRIPGGPAV-ANSVARKHGFLNLGQIF-GDYYHFWHRGVTKRSLSPHRPRH 84
++ +TN WAVRI GG AN +A K+G+ NLG I GD Y+ + R K+S S + R
Sbjct 55 RRTYTNEWAVRIAGGKVEEANRLANKYGYTNLGPIIPGDEYYLF-RDDRKKSRSSRKTRS 113
Query 85 ---SRLQREPQVQWLEQQVAKRRTKR------------DVYQE----------------- 112
++LQ E V W+EQQVAKRR KR D+++E
Sbjct 114 LSANQLQHEEDVMWMEQQVAKRRVKRGYRRIRRHTDDNDIFEEDDDGTQISKSRNRKHPD 173
Query 113 PTDPKFPQQWYLS-------GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG 165
P DP + WYL+ T+ D NVK AW GYTG G+VV+ILDDG+E+ HPD++
Sbjct 174 PNDPLWTDMWYLNRGEHHSDSTTRMDHNVKEAWDLGYTGKGVVVTILDDGLERTHPDISP 233
Query 166 NYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVR 225
NYD AS+DVND+D DP PRY ++NRHGTRCAGEVAA+ NN +C VG+AYNA IGG+R
Sbjct 234 NYDERASYDVNDRDNDPMPRYEFSDENRHGTRCAGEVAAIFNNSLCIVGIAYNANIGGIR 293
Query 226 MLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGL 285
MLDG+VTDAVEA S+G N ++I IYSASWGP+DDG+TVDGPA+L AF +G++ GR G
Sbjct 294 MLDGDVTDAVEAASVGHNADYIDIYSASWGPDDDGRTVDGPAKLTRSAFEKGITMGRKGK 353
Query 286 GSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGN 345
GSIFVWASGNGG++ DSCNCDGYTNSIYTLSISSAT+ GN+PWYSEACSSTLATTYSSG
Sbjct 354 GSIFVWASGNGGKDADSCNCDGYTNSIYTLSISSATENGNIPWYSEACSSTLATTYSSGA 413
Query 346 QNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAH 405
EK I+TTDL CT HTGTSASAPLAAGI+AL LEAN NLTWRD+QH+V++T+KP +
Sbjct 414 TGEKMILTTDLHHACTNMHTGTSASAPLAAGIVALALEANPNLTWRDLQHIVIRTAKPIN 473
Query 406 LNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDI--GK 463
L A DW TNGVGR VSHS+GYGL+DAGAMV LA+ W V Q +C + K+I G
Sbjct 474 LRAGDWTTNGVGRNVSHSFGYGLMDAGAMVKLAKIWKKVDEQHRCRQFYPSRYKNIPNGN 533
Query 464 RLEVRKTVTACLG--EPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPH 521
RL+++ C G + N ++ +EH QA +TL +RGDL I+L SP GT+STLL R
Sbjct 534 RLQLQLYSDGCYGGADENKVSYVEHVQAIVTLKAPKRGDLQIYLTSPSGTKSTLLTKRAR 593
Query 522 DYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPE 576
D S GF DWAFMTTH+W E +G W+LEI+N + + L K+ LVLYGT E
Sbjct 594 DTSRSGFTDWAFMTTHNWGEQAAGLWILEIDN--DGWDDAELVKWELVLYGTDRE 646
>sp|P30430|FUR1C_DROME Furin-like protease 1, isoform 1-CRR OS=Drosophila
melanogaster OX=7227 GN=Fur1 PE=2 SV=2
Length=1101
Score = 643 bits (1659), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 327/578 (57%), Positives = 403/578 (70%), Gaps = 26/578 (4%)
Query 30 FTNTWAVRIPGGP-AVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQ 88
+T+TWAV IP G +A++VA+ HGF+NLG+IF D+YHF H V+KRSLSP +RL
Sbjct 231 YTHTWAVHIPNGDNGMADAVAKDHGFVNLGKIFDDHYHFAHHKVSKRSLSPATHHQTRLD 290
Query 89 REPQVQWLEQQVAKRRTKRD-VYQEPT----------------DPKFPQQWYLSGVTQRD 131
+ +V W +QQ AK R+KRD + P+ D K+PQ WYL+ D
Sbjct 291 DDDRVHWAKQQRAKSRSKRDFIRMRPSRTSSRAMSMVDAMSFNDSKWPQMWYLNRGGGLD 350
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND 191
+NV AW G TG G+VV+ILDDG+E +HPD+ NYDP AS+DVN D DP P Y +
Sbjct 351 MNVIPAWKMGITGKGVVVTILDDGLESDHPDIQDNYDPKASYDVNSHDDDPMPHYDMTDS 410
Query 192 NRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS 251
NRHGTRCAGEVAA ANN C VG+AY A +GGVRMLDG+VTDAVEARSL LNP HI IYS
Sbjct 411 NRHGTRCAGEVAATANNSFCAVGIAYGASVGGVRMLDGDVTDAVEARSLSLNPQHIDIYS 470
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
ASWGP+DDGKTVDGP LA AF G ++GRGG GSIF+WASGNGGRE D+CNCDGYTNS
Sbjct 471 ASWGPDDDGKTVDGPGELASRAFIEGTTKGRGGKGSIFIWASGNGGREQDNCNCDGYTNS 530
Query 312 IYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASA 371
I+TLSISSAT+ G+VPWYSE CSSTLATTYSSG Q EKQ+VTTDL CT SHTGTSASA
Sbjct 531 IWTLSISSATEEGHVPWYSEKCSSTLATTYSSGGQGEKQVVTTDLHHSCTVSHTGTSASA 590
Query 372 PLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDA 431
PLAAGI AL L++N+NLTWRD+QH+VV+T+KPA+L W+ NGVGR+VSHS+GYGL+DA
Sbjct 591 PLAAGIAALVLQSNQNLTWRDLQHIVVRTAKPANLKDPSWSRNGVGRRVSHSFGYGLMDA 650
Query 432 GAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARL 491
MV +A+NW V Q++C I+ K I R + T+ + + LEH QA++
Sbjct 651 AEMVRVARNWKAVPEQQRCEINAPHVDKVIPPRTHI--TLQLTVNHCRSVNYLEHVQAKI 708
Query 492 TLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEI 551
TL+ RRGD+ + L SP T TLL R HD S GFN W FM+ H+W E P G W LEI
Sbjct 709 TLTSQRRGDIQLFLRSPANTSVTLLTPRIHDNSRSGFNQWPFMSVHTWGESPQGNWQLEI 768
Query 552 ENTSEANNYGTLTKFTLVLYGTA----PEGLPVPPESS 585
N E +T++ ++ YGT P+ + P +S+
Sbjct 769 HN--EGRYMAQITQWDMIFYGTETPAQPDDVANPSQSN 804
>sp|Q9NJ15|PCSK5_BRACL Proprotein convertase subtilisin/kexin
type 5 OS=Branchiostoma californiense OX=7738 GN=PC6 PE=2 SV=1
Length=1696
Score = 631 bits (1628), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 361/777 (46%), Positives = 450/777 (58%), Gaps = 115/777 (15%)
Query 7 LLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--FGDY 64
L AA + L A G +++ N WA+ + GG A A+ +A KHGF+N GQI D+
Sbjct 8 LALFTAALCAVNLRTVAADGPRIYRNEWALHVEGGTAAADRLASKHGFINKGQIGSLEDH 67
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWL----------------------EQQV-- 100
Y F HR KRSL RH+ LQREP+V+WL EQ+V
Sbjct 68 YLFVHRRTWKRSLRSSSHRHALLQREPEVRWLQQQVVKRRVKRRVKRVYSMYPWEQRVQH 127
Query 101 ----AKRRTKRDVYQEP--TDPKFPQQWYLS------GVTQRDLNVKAAWAQGYTGHGIV 148
++D +P D K+ + WYL D+NV+AAW +GYTG G+V
Sbjct 128 SSPQVNNPAQQDNLWDPHFNDEKWDKMWYLHCDRPEFACQWSDMNVEAAWKKGYTGKGVV 187
Query 149 VSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANN 208
VSILDDG E +HPDLAGNYDP AS D+N DP PRY N+NRHGTRCAGEVAA+ NN
Sbjct 188 VSILDDGSETDHPDLAGNYDPDASSDINGGTLDPTPRYEYTNENRHGTRCAGEVAAMGNN 247
Query 209 GVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPAR 268
C VGVAY A IGGVRMLDG+VTD+VEA SLGLNP HI IYSASWGP+DDGKTVDGPA
Sbjct 248 SFCSVGVAYKASIGGVRMLDGDVTDSVEAASLGLNPQHIMIYSASWGPDDDGKTVDGPAN 307
Query 269 LAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPW 328
LA++ F G GR LGSIFVWASGNGGR HDSC CDGYTNSIYT+S+SSA++ G VPW
Sbjct 308 LAQKTFQAGAENGRDKLGSIFVWASGNGGRTHDSCGCDGYTNSIYTISVSSASEQGKVPW 367
Query 329 YSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNL 388
Y E C+STLATTYSSG +E++++TTDLR+ CTESHTGTSASAP+AAGI+AL LEAN L
Sbjct 368 YLEPCASTLATTYSSGAPHERKVITTDLRKGCTESHTGTSASAPMAAGILALALEANPML 427
Query 389 TWRDMQHLVVQTSKPAHLNAN-------------DWATNGVGRKVSHSYGYGLLDAGAMV 435
TWRDMQ++VV + P+ L+ + D+ TNG G +VSH++G+GL+DAG MV
Sbjct 428 TWRDMQYIVVMAANPSPLDRDTESAYPRDPRKESDFVTNGAGLRVSHNFGFGLMDAGKMV 487
Query 436 ALAQNWTTVAPQRKCIIDILTEPKDI--GKRLEVRKTVTACLGEPNHITRLEHAQARLTL 493
LA++W V Q C D + + I G+ + KT C G +H+ LEH ++L
Sbjct 488 ELAESWRRVPEQHVCEEDPNAQQRAITKGETIVDTKTTGGCNGTDHHVKYLEHVVVEISL 547
Query 494 SYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIEN 553
+ RG L+IH+ SP GTRSTLL R D S+DG DWAFMTTH W E P G+W+LE+++
Sbjct 548 DHPCRGHLSIHITSPSGTRSTLLPERQFDSSSDGLKDWAFMTTHCWGEQPEGDWILEVKD 607
Query 554 TSEAN--NYG------TLTKFTLVLYGTA--------PEGLPVPPESSG----------- 586
+ N YG L K+ L+LYGTA E P P++
Sbjct 608 LGQQNCQRYGLRTVLPVLRKWKLILYGTAEHPLYKRDEESRPHTPQTREEPTDEEECEDG 667
Query 587 ---------CKTLTSSQA---------CVVCEEG--FSLHQKSCVQHCPPGFAPQVLDTH 626
C+ S A C+ C EG F + +C + C G+
Sbjct 668 DYYDRSKQRCRHCHDSCATCHGRHSGQCLSCHEGNYFVEDEGTCSEECGQGY-------- 719
Query 627 YSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
Y E + + C C A C TCQ A C SC L E TC Q R
Sbjct 720 YKDEEERK------CLDCSADCLTCQVSA-DHCTSCDDEDGLKLFENTCVAQCSEGR 769
Score = 41.2 bits (95), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 28/91 (31%), Positives = 36/91 (40%), Gaps = 18/91 (20%)
Query 587 CKTLTSSQA--CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPC 644
C T T A CV C + L + CV+ C G+ Q + C C
Sbjct 784 CDTCTGPDATDCVTCADEDLLQESQCVESCSSGYFQQEYE----------------CLKC 827
Query 645 HASCATCQGPALTDCLSCPSHASLDPVEQTC 675
HA+CA+C G CL+C H LD C
Sbjct 828 HATCASCSGSRDDQCLTCSGHLELDEDTHRC 858
Score = 40.8 bits (94), Expect = 0.069, Method: Compositional matrix adjust.
Identities = 30/82 (37%), Positives = 37/82 (45%), Gaps = 18/82 (22%)
Query 584 SSGCKTL-TSSQACVVC--EEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASV 640
S+ C T S+ C C E+G L + +CV C G Y ENDV
Sbjct 732 SADCLTCQVSADHCTSCDDEDGLKLFENTCVAQCSEG--------RYMDENDV------- 776
Query 641 CAPCHASCATCQGPALTDCLSC 662
C C SC TC GP TDC++C
Sbjct 777 CQDCDDSCDTCTGPDATDCVTC 798
Score = 38.1 bits (87), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 21/67 (31%), Positives = 32/67 (48%), Gaps = 7/67 (10%)
Query 596 CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPA 655
C+ C+ G L+ + C HCP G + + ++ ET+ C CH +C TC G
Sbjct 1351 CLSCQPGSYLNDQQCSTHCPEGTFEETYE-----DDSGETVLQ--CRLCHVNCKTCHGEG 1403
Query 656 LTDCLSC 662
DC+ C
Sbjct 1404 EEDCMEC 1410
Score = 38.1 bits (87), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 25/71 (35%), Positives = 33/71 (46%), Gaps = 14/71 (20%)
Query 592 SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATC 651
++Q C C+EGF C CP + +Y + + E C PC +SC TC
Sbjct 1080 NNQNCNSCKEGFYKTPDGCSTGCP--------NRYYKDDTNKE------CKPCDSSCFTC 1125
Query 652 QGPALTDCLSC 662
GPA CLSC
Sbjct 1126 SGPASFHCLSC 1136
Score = 37.0 bits (84), Expect = 1.00, Method: Compositional matrix adjust.
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 15/74 (20%)
Query 596 CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASV-CAPCHASCATCQGP 654
CV C + L C++ CP G+ +T+R C CH SCATC
Sbjct 1456 CVTCPYNYYLVLGKCLEDCPEGY--------------YDTMRQEKECGECHPSCATCNEG 1501
Query 655 ALTDCLSCPSHASL 668
+CLSCP + L
Sbjct 1502 GNYNCLSCPYGSKL 1515
Score = 36.6 bits (83), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 27/82 (33%), Positives = 34/82 (41%), Gaps = 19/82 (23%)
Query 596 CVVCEEGFSL-HQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGP 654
C C +GF L SC CPPG + + C CH C TC GP
Sbjct 1303 CTACNDGFLLTDASSCEAGCPPG----------------QFLHHGDCDSCHRECKTCDGP 1346
Query 655 ALTDCLSCPSHASLDPVEQTCS 676
+CLSC + L+ +Q CS
Sbjct 1347 HHDNCLSCQPGSYLN--DQQCS 1366
Score = 36.2 bits (82), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 47/142 (33%), Gaps = 59/142 (42%)
Query 580 VPPESSGCKTLT--SSQACVVCEEGFSLHQKSCVQHCPPGFAPQV-----------LDTH 626
P S C T + +S C+ C +G LH+ SC CP GF D +
Sbjct 1115 CKPCDSSCFTCSGPASFHCLSCADGDFLHESSCRSTCPAGFIGNAESHECVESSCEQDQY 1174
Query 627 YSTE---------------NDVETIRAS-------------------------------V 640
YS+E ND + +
Sbjct 1175 YSSETGRCEDCPYNCRACDNDGDCAECAPTYIVVDGRCRPEETCEDGEYQDRDRDTAELS 1234
Query 641 CAPCHASCATCQGPALTDCLSC 662
C PCH SC TC GP+ TDC SC
Sbjct 1235 CRPCHQSCKTCSGPSDTDCDSC 1256
>sp|P30432|FUR2_DROME Furin-like protease 2 OS=Drosophila melanogaster
OX=7227 GN=Fur2 PE=2 SV=2
Length=1679
Score = 603 bits (1556), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 329/626 (53%), Positives = 389/626 (62%), Gaps = 71/626 (11%)
Query 27 QKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--FGDYYHFWHRGVTKRSLSPHRPRH 84
+ ++TN +AV IP G +A+ +A KHGF+N GQI +YY F H V+KRSL R
Sbjct 236 EAIYTNEFAVNIPAGKQMADVIATKHGFINRGQIGSLDNYYLFQHHHVSKRSLRSSRKHQ 295
Query 85 SRLQREPQVQWLEQQVAKRRTKRD-VYQE-PT---------------------------- 114
L+ E +V+W++QQ K R KRD YQ+ PT
Sbjct 296 GALKSENEVKWMQQQHEKVRRKRDGPYQDLPTYSPYNLLRQHGGYVVDPNPHLSFSPESI 355
Query 115 ---------------------DPKFPQQWYLSGVTQR--DLNVKAAWAQGYTGHGIVVSI 151
DP F +QWYL+G + D+NV AW +GYTG G+VVSI
Sbjct 356 SLASHSQRMEYRDVSSHFIFPDPLFKEQWYLNGGAKDGLDMNVGPAWQKGYTGKGVVVSI 415
Query 152 LDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVC 211
LDDGI+ NHPDLA NYDP ASFD+N D DP P+ DN+HGTRCAGEVAAVA N C
Sbjct 416 LDDGIQTNHPDLAQNYDPEASFDINGNDSDPTPQ--DNGDNKHGTRCAGEVAAVAFNNFC 473
Query 212 GVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAE 271
GVGVAYNA IGGVRMLDG+V D VEA++L LNP+HI IYSASWGPEDDG TVDGP LA
Sbjct 474 GVGVAYNASIGGVRMLDGKVNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPGPLAR 533
Query 272 EAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSE 331
AF GV+ GR G GSIFVWASGNGGR DSCNCDGYTNSI+TLSISSATQ G PWY E
Sbjct 534 RAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKPWYLE 593
Query 332 ACSSTLATTYSSGNQ-NEKQIVTTDL------RQKCTESHTGTSASAPLAAGIIALTLEA 384
CSSTLATTYSSG ++K + T D+ CT HTGTSASAPLAAGI AL LEA
Sbjct 594 ECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDHICTVEHTGTSASAPLAAGICALALEA 653
Query 385 NKNLTWRDMQHLVVQTSKPAHLNA-NDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTT 443
N LTWRDMQ+LVV TS+PA L N W NGV RK SH +GYGL+DAGAMV+LA+ WT+
Sbjct 654 NPELTWRDMQYLVVYTSRPAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAEQWTS 713
Query 444 VAPQRKCIIDILTEPKDI----GKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRG 499
V PQ C E + I G L V C G N + LEH Q R+TL + RG
Sbjct 714 VPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGCAGTINEVRYLEHVQCRITLRFFPRG 773
Query 500 DLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIEN--TSEA 557
+L I L SPMGT STLL RP D F+DW F++ H W E G W L++ N
Sbjct 774 NLRILLTSPMGTTSTLLFERPRDIVKSNFDDWPFLSVHFWGEKAEGRWTLQVINGGRRRV 833
Query 558 NNYGTLTKFTLVLYGTAPEGLPVPPE 583
N G L+K+ L+ YGT+ + + + E
Sbjct 834 NQPGILSKWQLIFYGTSTQPMRLKSE 859
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 31/93 (33%), Positives = 47/93 (51%), Gaps = 11/93 (12%)
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQK-SCVQHCPPGFAPQVLDTHYSTENDVETI 636
L P GCKT TS+ C C + ++L+++ C+ V + +E++ +
Sbjct 1157 LECMPCQEGCKTCTSNGVCSECLQNWTLNKRDKCI----------VSGSEGCSESEFYSQ 1206
Query 637 RASVCAPCHASCATCQGPALTDCLSCPSHASLD 669
C PCHASC +C GPA T C SCP + L+
Sbjct 1207 VEGQCRPCHASCGSCNGPADTSCTSCPPNRLLE 1239
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 17/87 (20%)
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
+P P + C+ + C C+ +H+ C CP LDT+ + +N
Sbjct 1064 VPCEPNCASCQD--HPEYCTSCDHHLVMHEHKCYSACP-------LDTYETEDNK----- 1109
Query 638 ASVCAPCHASCATCQGPALTDCLSCPS 664
CA CH++CATC GP DC++C S
Sbjct 1110 ---CAFCHSTCATCNGPTDQDCITCRS 1133
Score = 40.0 bits (92), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 23/78 (29%), Positives = 29/78 (37%), Gaps = 16/78 (21%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C S C C +G L C C G+ YS +CA C+
Sbjct 1266 CSQCVSRTNCSNCSKGLELQNGECRTTCADGY--------YSDR--------GICAKCYL 1309
Query 647 SCATCQGPALTDCLSCPS 664
SC TC GP C+ CP+
Sbjct 1310 SCHTCSGPRRNQCVQCPA 1327
Score = 39.3 bits (90), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 28/84 (33%), Positives = 37/84 (44%), Gaps = 19/84 (23%)
Query 583 ESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCA 642
+SSGC +Q CV C + L +CV CPP P + +C
Sbjct 972 DSSGCYGRGPTQ-CVACSH-YRL-DNTCVSRCPPRSFPN---------------QVGICW 1013
Query 643 PCHASCATCQGPALTDCLSC-PSH 665
PCH +C TC G CL+C P+H
Sbjct 1014 PCHDTCETCAGAGPDSCLTCAPAH 1037
Score = 37.7 bits (86), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 23/74 (31%), Positives = 25/74 (34%), Gaps = 16/74 (22%)
Query 596 CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPA 655
CV C G+ L C CP GF C CH C TC
Sbjct 1322 CVQCPAGWQLAAGECHPECPEGFYKSDFG----------------CQKCHHYCKTCNDAG 1365
Query 656 LTDCLSCPSHASLD 669
C SCP H+ LD
Sbjct 1366 PLACTSCPPHSMLD 1379
>sp|P63239|NEC1_MOUSE Neuroendocrine convertase 1 OS=Mus musculus
OX=10090 GN=Pcsk1 PE=1 SV=1
Length=753
Score = 588 bits (1516), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 330/757 (44%), Positives = 454/757 (60%), Gaps = 52/757 (7%)
Query 1 MELRPWLLWVVAATGTLVLLAADA-QGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQ 59
ME R W L A V A ++ + ++ F N WA IPGG A+++A + G+ LGQ
Sbjct 1 MEQRGWTLQCTAFAFFCVWCALNSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQ 60
Query 60 I--FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP---- 113
I ++Y F H+ +RS RL + +V W EQQ K R+KR V ++
Sbjct 61 IGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDL 120
Query 114 -TDPKFPQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
DP + QQWYL + + + DL+V W +G TG G+V+++LDDG+E NH D+ N
Sbjct 121 FNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYAN 180
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
YDP AS+D ND D DP PRY N+N+HGTRCAGE+A ANN CGVGVAYN+++GG+RM
Sbjct 181 YDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM 240
Query 227 LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLG 286
LDG VTDA+EA S+G NP H+ IYSASWGP DDGKTV+GP RLA++AF GV QGR G G
Sbjct 241 LDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG 300
Query 287 SIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ 346
SIFVWASGNGGR+ D+C+CDGYT+SIYT+SISSA+Q G PWY+E CSSTLAT+YSSG+
Sbjct 301 SIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY 360
Query 347 NEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
+++I + DL CTE+HTGTSASAPLAAGI AL LEAN NLTWRDMQHLVV TS+ L
Sbjct 361 TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL 420
Query 407 NAN-DWATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCII-DILTEPKDIG 462
+N W NG G V+ +G+GLL+A A+V LA + W V +++C++ D EP+ +
Sbjct 421 ASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALK 480
Query 463 KRLEVRKTV--TACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARP 520
EV + AC G+ N I LEH Q T+ Y+RRGDL + L S +GT + LLA R
Sbjct 481 ANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERE 540
Query 521 HDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS-EANNYGTLTKFTLVLYGTA--PEG 577
D S +GF +W FM+ H+W E+P G W L+I + S N G + + L+L+GT+ PE
Sbjct 541 RDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEH 600
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
+ P + T+ + + V E+ ++ +K Q +++
Sbjct 601 MKQPRVYTSYNTVQNDRRGV--EKMVNVVEKRPTQ---------------------KSLN 637
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS---QSSRESPPQQQPPRL 694
++ P ++S + +G PS A L ++ S+ + QS ++SP +
Sbjct 638 GNLLVPKNSSSSNVEGRRDEQVQGTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPY 697
Query 695 PPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVT 731
EA ++L PS L L ++ + + T
Sbjct 698 ESFYEALEKLNK---PSKLEGSEDSLYSDYVDVFYNT 731
>sp|P63240|NEC1_MUSCO Neuroendocrine convertase 1 OS=Mus cookii
OX=10098 GN=Pcsk1 PE=2 SV=1
Length=753
Score = 588 bits (1515), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 330/757 (44%), Positives = 453/757 (60%), Gaps = 52/757 (7%)
Query 1 MELRPWLLWVVAATGTLVLLA-ADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQ 59
ME R W L A V A + + ++ F N WA IPGG A+++A + G+ LGQ
Sbjct 1 MEQRGWTLQCTAFAFFCVWCALSSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQ 60
Query 60 I--FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP---- 113
I ++Y F H+ +RS RL + +V W EQQ K R+KR V ++
Sbjct 61 IGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDL 120
Query 114 -TDPKFPQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
DP + QQWYL + + + DL+V W +G TG G+V+++LDDG+E NH D+ N
Sbjct 121 FNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYAN 180
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
YDP AS+D ND D DP PRY N+N+HGTRCAGE+A ANN CGVGVAYN+++GG+RM
Sbjct 181 YDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM 240
Query 227 LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLG 286
LDG VTDA+EA S+G NP H+ IYSASWGP DDGKTV+GP RLA++AF GV QGR G G
Sbjct 241 LDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG 300
Query 287 SIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ 346
SIFVWASGNGGR+ D+C+CDGYT+SIYT+SISSA+Q G PWY+E CSSTLAT+YSSG+
Sbjct 301 SIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY 360
Query 347 NEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
+++I + DL CTE+HTGTSASAPLAAGI AL LEAN NLTWRDMQHLVV TS+ L
Sbjct 361 TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL 420
Query 407 NAN-DWATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCII-DILTEPKDIG 462
+N W NG G V+ +G+GLL+A A+V LA + W V +++C++ D EP+ +
Sbjct 421 ASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALK 480
Query 463 KRLEVRKTV--TACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARP 520
EV + AC G+ N I LEH Q T+ Y+RRGDL + L S +GT + LLA R
Sbjct 481 ANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERE 540
Query 521 HDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS-EANNYGTLTKFTLVLYGTA--PEG 577
D S +GF +W FM+ H+W E+P G W L+I + S N G + + L+L+GT+ PE
Sbjct 541 RDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEH 600
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
+ P + T+ + + V E+ ++ +K Q +++
Sbjct 601 MKQPRVYTSYNTVQNDRRGV--EKMVNVVEKRPTQ---------------------KSLN 637
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS---QSSRESPPQQQPPRL 694
++ P ++S + +G PS A L ++ S+ + QS ++SP +
Sbjct 638 GNLLVPKNSSSSNVEGRRDEQVQGTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPY 697
Query 695 PPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVT 731
EA ++L PS L L ++ + + T
Sbjct 698 ESFYEALEKLNK---PSKLEGSEDSLYSDYVDVFYNT 731
>sp|P28840|NEC1_RAT Neuroendocrine convertase 1 OS=Rattus norvegicus
OX=10116 GN=Pcsk1 PE=2 SV=1
Length=752
Score = 582 bits (1499), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 329/756 (44%), Positives = 452/756 (60%), Gaps = 51/756 (7%)
Query 1 MELRPWLLWVVAATGTLVLLAADA-QGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQ 59
M+ R W L A T V A ++ + ++ F N WA I GGP A+++A + G+ LGQ
Sbjct 1 MKQRGWTLQCTAFTLFCVWCALNSVKAKRQFVNEWAAEIHGGPEAASAIAEELGYDLLGQ 60
Query 60 I--FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP---- 113
I ++Y F H+ +RS RL + +V W EQQ K R KR V ++
Sbjct 61 IGSLENHYLFKHKNHPRRSRRSALHITKRLSDDDRVIWAEQQYEKERRKRSVPRDSALNL 120
Query 114 -TDPKFPQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
DP + QQWYL + + + DL+V W +G TG G+V+++LDDG+E NH D+ N
Sbjct 121 FNDPMWNQQWYLQDTRMTASLPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYAN 180
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
YDP AS+D ND D DP PRY N+N+HGTRCAGE+A ANN CGVGVAYN+++GG+RM
Sbjct 181 YDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM 240
Query 227 LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLG 286
LDG VTDA+EA S+G NP H+ IYSASWGP DDGKTV+GP RLA++AF GV QGR G G
Sbjct 241 LDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG 300
Query 287 SIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ 346
SIFVWASGNGGR+ D+C+CDGYT+SIYT+SISSA+Q G PWY+E CSSTLAT+YSSG+
Sbjct 301 SIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY 360
Query 347 NEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
+++I + DL CTE+HTGTSASAPLAAGI AL LEAN NLTWRDMQHLVV TS+ L
Sbjct 361 TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL 420
Query 407 NAN-DWATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCII-DILTEPKDIG 462
N W NG G V+ +G+GLL+A A+V LA + W V +++CII D EP+ +
Sbjct 421 ANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECIIKDNNFEPRALK 480
Query 463 KRLEVRKTV--TACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARP 520
EV + AC G+ N I LEH Q T+ Y+RRGDL + L S GT + LLA R
Sbjct 481 ANGEVIVEIPTRACEGQENAINSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERE 540
Query 521 HDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS-EANNYGTLTKFTLVLYGTA--PEG 577
D S +GF +W FM+ H+W E+P G W L++ + S N G + + L+L+GT+ PE
Sbjct 541 RDTSPNGFKNWDFMSVHTWGENPVGTWTLKVTDMSGRMQNEGRIVNWKLILHGTSSQPEH 600
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
+ P + T+ + + V E+ ++ ++ Q+ ++
Sbjct 601 MKQPRVYTSYNTVQNDRRGV--EKMVNVVEEKPTQN---------------------SLN 637
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPE 697
++ P ++S ++ + PS A L ++ S+ + S + S +P E
Sbjct 638 GNLLVPKNSSSSSVEDRRDEQVQGAPSKAMLRLLQSAFSKNTPSKQSSKIPSAKLSVPYE 697
Query 698 --VEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVT 731
EA ++L PS L + L ++ + + T
Sbjct 698 GLYEALEKLNK---PSQLEDSEDSLYSDYVDVFYNT 730
>sp|P29120|NEC1_HUMAN Neuroendocrine convertase 1 OS=Homo sapiens
OX=9606 GN=PCSK1 PE=1 SV=2
Length=753
Score = 582 bits (1499), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 307/608 (50%), Positives = 397/608 (65%), Gaps = 31/608 (5%)
Query 1 MELRPWLLWVVAATGTLVLLAA-----DAQGQKVFTNTWAVRIPGGPAVANSVARKHGFL 55
ME R W L A VL A A+ ++ F N WA IPGGP A+++A + G+
Sbjct 1 MERRAWSLQCTA----FVLFCAWCALNSAKAKRQFVNEWAAEIPGGPEAASAIAEELGYD 56
Query 56 NLGQI--FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP 113
LGQI ++Y F H+ +RS RL + +V W EQQ K R+KR ++
Sbjct 57 LLGQIGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDS 116
Query 114 -----TDPKFPQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPD 162
DP + QQWYL + + + DL+V W +G TG G+V+++LDDG+E NH D
Sbjct 117 ALNLFNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTD 176
Query 163 LAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIG 222
+ NYDP AS+D ND D DP PRY N+N+HGTRCAGE+A ANN CGVGVAYN+++G
Sbjct 177 IYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVG 236
Query 223 GVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGR 282
G+RMLDG VTDA+EA S+G NP H+ IYSASWGP DDGKTV+GP RLA++AF GV QGR
Sbjct 237 GIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGR 296
Query 283 GGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYS 342
G GSIFVWASGNGGR+ D+C+CDGYT+SIYT+SISSA+Q G PWY+E CSSTLAT+YS
Sbjct 297 QGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYS 356
Query 343 SGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSK 402
SG+ +++I + DL CTE+HTGTSASAPLAAGI AL LEAN NLTWRDMQHLVV TS+
Sbjct 357 SGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSE 416
Query 403 PAHLNAN-DWATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCII-DILTEP 458
L N W NG G V+ +G+GLL+A A+V LA + W +V +++C++ D EP
Sbjct 417 YDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEP 476
Query 459 KDIGKRLEVRKTV--TACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLL 516
+ + EV + AC G+ N I LEH Q T+ Y+RRGDL + L S GT + LL
Sbjct 477 RALKANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLL 536
Query 517 AARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS-EANNYGTLTKFTLVLYGTA- 574
A R D S +GF +W FM+ H+W E+P G W L I + S N G + + L+L+GT+
Sbjct 537 AERERDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSS 596
Query 575 -PEGLPVP 581
PE + P
Sbjct 597 QPEHMKQP 604
>sp|Q9GLR1|NEC1_BOVIN Neuroendocrine convertase 1 OS=Bos taurus
OX=9913 GN=PCSK1 PE=2 SV=1
Length=753
Score = 579 bits (1493), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 304/604 (50%), Positives = 398/604 (66%), Gaps = 23/604 (4%)
Query 1 MELRPWLLWVVAATGTLVLLAADA-QGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQ 59
M R W L A + A ++ + +K F N WA IPGGP A+++A++ G+ LGQ
Sbjct 1 MGRRAWTLQCTAFSLFCAWCAMNSVKAKKQFVNEWAAEIPGGPEAASAIAQELGYDLLGQ 60
Query 60 I--FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP---- 113
I ++Y F HR +RS RL + +V W EQQ K R+KR V ++
Sbjct 61 IGSLENHYLFKHRNHPRRSRRSALHITKRLSDDDRVIWAEQQYEKERSKRSVLRDSALDL 120
Query 114 -TDPKFPQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
DP + QQWYL + + + DL+V W +G TG G+V+++LDDG+E NH D+ N
Sbjct 121 FNDPMWNQQWYLQDTRMTATLPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYAN 180
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
YDP AS+D ND D DP PRY +N+N+HGTRCAGE+A ANN CGVGVAYN+++GG+RM
Sbjct 181 YDPEASYDFNDNDHDPFPRYDLINENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM 240
Query 227 LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLG 286
LDG VTDA+EA +G NP H+ IYSASWGP DDGKTV+GP RLA++AF GV QGR G G
Sbjct 241 LDGIVTDAIEASLIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG 300
Query 287 SIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ 346
SIFVWASGNGGR+ D+C+CDGYT+SIYT+SI+SA+Q G PWY+E CSSTLAT+YSSG+
Sbjct 301 SIFVWASGNGGRQGDNCDCDGYTDSIYTISINSASQQGLSPWYAEKCSSTLATSYSSGDY 360
Query 347 NEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
+++I + DL CTE+HTGTSASAPLAAGI AL LEAN NLTWRDMQHLVV TS+ L
Sbjct 361 TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL 420
Query 407 NAN-DWATNGVGRKVSHSYGYGLLDAGAMVALAQ--NWTTVAPQRKCII-DILTEPKDIG 462
N W NG G V+ +G+GLL+A A+V LA W++V +++C++ D EP+ +
Sbjct 421 ANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPSTWSSVPEKKECVVKDNDFEPRALK 480
Query 463 KRLEVRKTV--TACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARP 520
EV + AC G+ N I LEH Q T+ Y+RRGDL + L S GT + LLA R
Sbjct 481 ANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERE 540
Query 521 HDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS-EANNYGTLTKFTLVLYGTA--PEG 577
D S +GF +W FM+ H+W E+P G W L I + S N G + + L+L+GT+ PE
Sbjct 541 RDTSPNGFKNWDFMSVHTWGENPIGTWTLRIADMSGRIQNEGRIVTWKLILHGTSSQPEH 600
Query 578 LPVP 581
+ P
Sbjct 601 MKQP 604
>sp|P51559|BLI4_CAEEL Endoprotease bli-4 OS=Caenorhabditis elegans
OX=6239 GN=bli-4 PE=1 SV=3
Length=942
Score = 538 bits (1387), Expect = 5e-178, Method: Compositional matrix adjust.
Identities = 292/579 (50%), Positives = 361/579 (62%), Gaps = 52/579 (9%)
Query 44 VANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKR 103
+A +A H G F D ++F + T R+ R RL P V+W+E+Q K+
Sbjct 53 LARRIAADHDMHVKGDPFLDTHYFLYHSETTRTRRHKRAIVERLDSHPAVEWVEEQRPKK 112
Query 104 RTKRDVY---------------------------QEPT-----------DPKFPQQWYLS 125
R KRD Q+P DP + QWYL
Sbjct 113 RVKRDYILLDNDVHHSNPFRRSVLNRDGTRRAQRQQPQSPREIPSLPFPDPLYKDQWYLH 172
Query 126 G--VTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQ 183
G V D+NV+ AW QGY G + VSILDDGI+++HPDLA NYDP AS D+ND D DP
Sbjct 173 GGAVGGYDMNVRQAWLQGYAGRNVSVSILDDGIQRDHPDLAANYDPLASTDINDHDDDPT 232
Query 184 PRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN 243
P+ DN+HGTRCAGEVAA+A N CGVGVA+ A+IGGVRMLDG V+D+VEA SL LN
Sbjct 233 PQ--NNGDNKHGTRCAGEVAALAGNNQCGVGVAFKAKIGGVRMLDGAVSDSVEAASLSLN 290
Query 244 PNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSC 303
+HI IYSASWGPEDDGKT DGP LA EAF+RG+ GRGG G+IFVWASGNGG DSC
Sbjct 291 QDHIDIYSASWGPEDDGKTFDGPGPLAREAFYRGIKNGRGGKGNIFVWASGNGGSRQDSC 350
Query 304 NCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTES 363
+ DGYT S+YTLSISSAT + PWY E C S++ATTYSS + + IVT D+ CT+
Sbjct 351 SADGYTTSVYTLSISSATYDNHRPWYLEECPSSIATTYSSADFRQPAIVTVDVPGGCTDK 410
Query 364 HTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAN-DWATNGVGRKVSH 422
HTGTSASAPLAAGIIAL LEAN LTWRDMQHLV++T+ L N W+ NGVGR VS+
Sbjct 411 HTGTSASAPLAAGIIALALEANPELTWRDMQHLVLRTANWKPLENNPGWSRNGVGRMVSN 470
Query 423 SYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILT---EPKDIGKRLEVRKT--VTAC-LG 476
+GYGL+D GA+V +A+ W TV Q C + P+ I R ++ T V C G
Sbjct 471 KFGYGLIDGGALVNMAKTWKTVPEQHICTYEYRLANPNPRPIVGRFQLNFTLDVNGCESG 530
Query 477 EPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTT 536
P + LEH Q T+ Y +RGDL + L SP GTRS LL RP D++A+GF+ W F++
Sbjct 531 TP--VLYLEHVQVHATVRYLKRGDLKLTLFSPSGTRSVLLPPRPQDFNANGFHKWPFLSV 588
Query 537 HSWDEDPSGEWVLEIEN-TSEANNYGTLTKFTLVLYGTA 574
W EDP G W+L +E+ T+ GT +TL+LYGTA
Sbjct 589 QQWGEDPRGTWLLMVESVTTNPAATGTFHDWTLLLYGTA 627
>sp|A0A044RE18|BLI_ONCVO Endoprotease bli OS=Onchocerca volvulus
OX=6282 GN=Bli PE=1 SV=1
Length=693
Score = 528 bits (1361), Expect = 3e-177, Method: Compositional matrix adjust.
Identities = 290/586 (49%), Positives = 366/586 (62%), Gaps = 52/586 (9%)
Query 45 ANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH-SRLQREPQVQWLEQQVAKR 103
A+ +A++HG GQ F D ++ ++K+ + SRLQ P + +E+Q +
Sbjct 53 AHLIAKQHGLEIRGQPFLDGKSYFVTHISKQRSRRRKREIISRLQEHPDILSIEEQRPRV 112
Query 104 RTKRDVY-----------------------QEPT--------------DPKFPQQWYLSG 126
R KRD EP DP + +QWYL+
Sbjct 113 RRKRDFLYPDIAHELAGSSTNIRHTGLISNTEPRIDFIQHDAPVLPFPDPLYKEQWYLNN 172
Query 127 VTQ--RDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQP 184
Q D+NV+AAW GY G I VSILDDGI+++HPDLA NYDP AS D+N D DP P
Sbjct 173 GAQGGFDMNVQAAWLLGYAGRNISVSILDDGIQRDHPDLAANYDPLASTDINGHDDDPTP 232
Query 185 RYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNP 244
+ DN+HGTRCAGEVA++A N CGVGVA++A+IGGVRMLDG V+D+VEA SL LN
Sbjct 233 Q--DDGDNKHGTRCAGEVASIAGNVYCGVGVAFHAKIGGVRMLDGPVSDSVEAASLSLNR 290
Query 245 NHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCN 304
+HI IYSASWGPEDDG+T DGP LA EAF+RGV GRGG GSIFVWASGNGG DSC+
Sbjct 291 HHIDIYSASWGPEDDGRTFDGPGPLAREAFYRGVKAGRGGKGSIFVWASGNGGSRQDSCS 350
Query 305 CDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESH 364
DGYT S+YTLS+SSAT PWY E C ST+ATTYSS N N+ I+T D+ CT SH
Sbjct 351 ADGYTTSVYTLSVSSATIDNRSPWYLEECPSTIATTYSSANMNQPAIITVDVPHGCTRSH 410
Query 365 TGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPA-HLNANDWATNGVGRKVSHS 423
TGTSASAPLAAGIIAL LEAN NLTWRDMQH+V++T+ P LN W+ NGVGR++++
Sbjct 411 TGTSASAPLAAGIIALALEANPNLTWRDMQHIVLRTANPVPLLNNPGWSVNGVGRRINNK 470
Query 424 YGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTE---PKDIGKRLEVRKT--VTAC-LGE 477
+GYGL+DAGA+V LA W TV Q C D E P+ I ++ + V C G
Sbjct 471 FGYGLMDAGALVKLALIWKTVPEQHICTYDYKLEKPNPRPITGNFQMNFSLEVNGCESGT 530
Query 478 PNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTH 537
P + LEH Q T + +RGDL + L SP GT S LL RP D++++G + W F++
Sbjct 531 P--VLYLEHVQVLATFRFGKRGDLKLTLFSPRGTSSVLLPPRPQDFNSNGIHKWPFLSVQ 588
Query 538 SWDEDPSGEWVLEIENTSEANNY-GTLTKFTLVLYGTAPEGLPVPP 582
+W EDP G+W L +E+ S N GT ++L+LYGTA P P
Sbjct 589 TWGEDPRGKWTLMVESVSTNRNVGGTFHDWSLLLYGTAEPAQPNDP 634
>sp|Q5REC2|NEC2_PONAB Neuroendocrine convertase 2 OS=Pongo abelii
OX=9601 GN=PCSK2 PE=2 SV=1
Length=638
Score = 511 bits (1317), Expect = 2e-171, Method: Compositional matrix adjust.
Identities = 281/585 (48%), Positives = 369/585 (63%), Gaps = 24/585 (4%)
Query 12 AATGTLVLLAADAQGQK-VFTNTWAVRI-PGGPAVANSVARKHGFLNLGQIFGD-YYHFW 68
AA G L + A ++ VFTN + V + GG A VA +HGF F + YHF+
Sbjct 11 AAAGFLFCVMVFASAERPVFTNHFLVELHKGGEDEARQVAAEHGFGVRKLPFAEGLYHFY 70
Query 69 HRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVA---KRRTKRDVYQ---EPTDPKFPQQW 122
H G+ K +L+R+P+V+ QQ K+R RD+ + DP F +QW
Sbjct 71 HNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQW 130
Query 123 YL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
YL G DLNV AW GYTG G+ + I+DDGI+ HPDLA NY+ AS+D +
Sbjct 131 YLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFS 190
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-VTDAV 235
DP P PRYT N HGTRCAGEV+A ANN +CGVGVAYN+++ G+RMLD +TD +
Sbjct 191 SNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDII 250
Query 236 EARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGN 295
EA S+ P I IYSASWGP D+GKTVDGP L +A GV++GRGG GSI+VWASG+
Sbjct 251 EASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGD 310
Query 296 GGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQN--EKQIVT 353
GG +D CNCDGY +S++T+SI+SA G Y E+CSSTLA+T+S+G + E + T
Sbjct 311 GG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVAT 369
Query 354 TDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN--ANDW 411
TDL CT H+GTSA+AP AAG+ AL LEAN LTWRDMQHL V TSK L+ + W
Sbjct 370 TDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQW 429
Query 412 ATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDI--GKRLEVRK 469
NGVG + +H +GYG+LDAGAMV +A++W TV + C+ + +P+ I +L +
Sbjct 430 RRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTL 489
Query 470 TVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD-GF 528
T AC G+ N + LEH QA +T++ RRGDL I++ SPMGT+S LL+ RP D + GF
Sbjct 490 TTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGF 549
Query 529 NDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGT 573
+ W FMTTH+W ED G W LE+ A G L ++TL+L+GT
Sbjct 550 DKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEWTLMLHGT 594
>sp|P16519|NEC2_HUMAN Neuroendocrine convertase 2 OS=Homo sapiens
OX=9606 GN=PCSK2 PE=1 SV=2
Length=638
Score = 511 bits (1316), Expect = 2e-171, Method: Compositional matrix adjust.
Identities = 281/585 (48%), Positives = 369/585 (63%), Gaps = 24/585 (4%)
Query 12 AATGTLVLLAADAQGQK-VFTNTWAVRI-PGGPAVANSVARKHGFLNLGQIFGD-YYHFW 68
AA G L + A ++ VFTN + V + GG A VA +HGF F + YHF+
Sbjct 11 AAAGFLFCVMVFASAERPVFTNHFLVELHKGGEDKARQVAAEHGFGVRKLPFAEGLYHFY 70
Query 69 HRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVA---KRRTKRDVYQ---EPTDPKFPQQW 122
H G+ K +L+R+P+V+ QQ K+R RD+ + DP F +QW
Sbjct 71 HNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEIDINMNDPLFTKQW 130
Query 123 YL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
YL G DLNV AW GYTG G+ + I+DDGI+ HPDLA NY+ AS+D +
Sbjct 131 YLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFS 190
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-VTDAV 235
DP P PRYT N HGTRCAGEV+A ANN +CGVGVAYN+++ G+RMLD +TD +
Sbjct 191 SNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDII 250
Query 236 EARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGN 295
EA S+ P I IYSASWGP D+GKTVDGP L +A GV++GRGG GSI+VWASG+
Sbjct 251 EASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGD 310
Query 296 GGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQN--EKQIVT 353
GG +D CNCDGY +S++T+SI+SA G Y E+CSSTLA+T+S+G + E + T
Sbjct 311 GG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVAT 369
Query 354 TDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN--ANDW 411
TDL CT H+GTSA+AP AAG+ AL LEAN LTWRDMQHL V TSK L+ + W
Sbjct 370 TDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQW 429
Query 412 ATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDI--GKRLEVRK 469
NGVG + +H +GYG+LDAGAMV +A++W TV + C+ + +P+ I +L +
Sbjct 430 RRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTL 489
Query 470 TVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD-GF 528
T AC G+ N + LEH QA +T++ RRGDL I++ SPMGT+S LL+ RP D + GF
Sbjct 490 TTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGF 549
Query 529 NDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGT 573
+ W FMTTH+W ED G W LE+ A G L ++TL+L+GT
Sbjct 550 DKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEWTLMLHGT 594
>sp|Q03333|NEC2_PIG Neuroendocrine convertase 2 OS=Sus scrofa
OX=9823 GN=PCSK2 PE=2 SV=1
Length=638
Score = 509 bits (1310), Expect = 2e-170, Method: Compositional matrix adjust.
Identities = 279/585 (48%), Positives = 369/585 (63%), Gaps = 24/585 (4%)
Query 12 AATGTLVLLAADAQGQK-VFTNTWAVRI-PGGPAVANSVARKHGFLNLGQIFGD-YYHFW 68
AA G L + A ++ VFTN + V + GG A VA +HGF F + YHF+
Sbjct 11 AAAGLLFCVTVFASAERPVFTNHFLVELHKGGEEEARQVAAEHGFGVRKLPFAEGLYHFY 70
Query 69 HRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVA---KRRTKRDVYQ---EPTDPKFPQQW 122
H G+ K RL+R+P+V+ QQ K+R RD+ + DP F +QW
Sbjct 71 HNGLAKAKRRRSLHHKQRLERDPRVKRALQQEGFDRKKRGYRDINEIDINMNDPLFTKQW 130
Query 123 YL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
YL G DLNV AW GYTG G+ + I+DDGI+ HPDLA NY+ AS+D +
Sbjct 131 YLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFS 190
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-VTDAV 235
DP P PRYT N HGTRCAGEV+A ANN +CGVGVAY++++ G+RMLD +TD +
Sbjct 191 SNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYSSKVAGIRMLDQPFMTDII 250
Query 236 EARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGN 295
EA S+ P I IYSASWGP D+GKTVDGP L +A GV++GRGG GSI+VWASG+
Sbjct 251 EASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGD 310
Query 296 GGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQN--EKQIVT 353
GG +D CNCDGY +S++T+SI+SA G Y E+CSSTLA+T+S+G + E + T
Sbjct 311 GG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVAT 369
Query 354 TDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN--ANDW 411
TDL CT H+GTSA+AP AAG+ AL LEAN LTWRDMQHL V TSK L+ + W
Sbjct 370 TDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQW 429
Query 412 ATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDI--GKRLEVRK 469
NGVG + +H +GYG+LDAGAMV +A++W TV + C+ + +P+ I +L +
Sbjct 430 RRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTL 489
Query 470 TVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD-GF 528
T AC G+ N + LEH QA +T++ RRGDL I++ SPMGT+S LL+ RP D + GF
Sbjct 490 TTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGF 549
Query 529 NDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGT 573
+ W FMTTH+W ED G W LE+ A G + ++TL+L+G+
Sbjct 550 DKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGAVKEWTLMLHGS 594
>sp|Q9VBC7|NEC2_DROME Neuroendocrine convertase 2 OS=Drosophila
melanogaster OX=7227 GN=amon PE=1 SV=1
Length=654
Score = 507 bits (1306), Expect = 1e-169, Method: Compositional matrix adjust.
Identities = 284/592 (48%), Positives = 369/592 (62%), Gaps = 53/592 (9%)
Query 29 VFTNTWAVRIPGG--PAVANSVARKHGFLNLGQIFG---DYYHFWHRGV----TKRSLSP 79
VFT+++ VR G + A+ VA K+GF NLG + G YHF HR + ++RSL+
Sbjct 39 VFTSSFLVRFRRGVDNSFAHDVADKYGFDNLGPLVGADGHEYHFKHRTLPHARSRRSLT- 97
Query 80 HRPRHSR-LQREPQVQWLEQQVAKRRTKRD----------------------VYQEPTDP 116
H+R L+ P V QQ +R KR + +EPTDP
Sbjct 98 ----HTRALKSHPAVHTAVQQPGFKRVKRGLRPAVPAIHGMKFDLKVGEGNRIDEEPTDP 153
Query 117 KFPQQWYLS------GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPG 170
FP QWYL G + DLNV+AAWAQG TG + +I+DDG++ HPDL NY+
Sbjct 154 YFPMQWYLKNTGQNGGKVRLDLNVQAAWAQGITGKNVTTAIMDDGVDYMHPDLKFNYNAE 213
Query 171 ASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG- 229
AS+D + DP P PRYT N HGTRCAGEVAA +NG+CGVGVAY+++I G+RMLD
Sbjct 214 ASYDFSSNDPFPYPRYTDDWFNSHGTRCAGEVAAARDNGICGVGVAYDSKIAGIRMLDQP 273
Query 230 EVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIF 289
+TD +EA S+G P+ IHIYSASWGP DDGKTVDGP A +GV++GR GLG+I+
Sbjct 274 YMTDLIEANSMGHEPHKIHIYSASWGPTDDGKTVDGPRNATMRAIVQGVNEGRNGLGNIY 333
Query 290 VWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEK 349
VWASG+GG E D CNCDGY S++T+SI+SA G Y E+CSSTLA+T+S+G ++
Sbjct 334 VWASGDGGEE-DDCNCDGYAASMWTISINSAINDGQNAHYDESCSSTLASTFSNGAKDPN 392
Query 350 Q-IVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL-- 406
+ TTDL KCT +H+GTSA+AP AAG+ AL LEAN LTWRD+QHL V TSK L
Sbjct 393 TGVATTDLYGKCTTTHSGTSAAAPEAAGVFALALEANPQLTWRDIQHLTVLTSKRNSLFD 452
Query 407 --NANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDI--G 462
N W NGVG + +H +G+G+LDAGAMV L++ W +V P+ C LT+P+ I G
Sbjct 453 AKNRFHWTMNGVGLEFNHLFGFGVLDAGAMVTLSKQWHSVPPRYHCEAGELTQPQAIVMG 512
Query 463 KRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHD 522
+ L AC G + LEH QA ++ + +RRGDL + L SPMGT+S +L+ R +D
Sbjct 513 RSLFWEIKTDACKGTDTEVNYLEHVQAVISANASRRGDLELFLTSPMGTKSMILSRRAND 572
Query 523 YS-ADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGT 573
DGF W FMTTHSW E P G W LE S +G L +++LVL+GT
Sbjct 573 DDHRDGFTKWPFMTTHSWGEYPQGTWKLEARFNSPQTRHGNLLEWSLVLHGT 624
>sp|Q9GLR0|NEC2_BOVIN Neuroendocrine convertase 2 OS=Bos taurus
OX=9913 GN=PCSK2 PE=2 SV=1
Length=638
Score = 506 bits (1304), Expect = 1e-169, Method: Compositional matrix adjust.
Identities = 281/586 (48%), Positives = 369/586 (63%), Gaps = 26/586 (4%)
Query 12 AATGTLVLLAADAQGQK-VFTNTWAVRI-PGGPAVANSVARKHGFLNLGQIFGD-YYHFW 68
AA G L + A ++ VFTN + V + GG A VA +HGF F + YHF+
Sbjct 11 AAAGLLFCVMVFASAERPVFTNHFLVELHRGGEEKARQVAAEHGFGVRKLPFAEGLYHFY 70
Query 69 HRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVA---KRRTKRDVYQ---EPTDPKFPQQW 122
H G+ K +L+R+P+V+ QQ K+R RD+ + DP F +QW
Sbjct 71 HNGLAKARRRRSLQHQQQLERDPRVKRALQQEGFNRKKRGYRDINEIDINVNDPLFTKQW 130
Query 123 YL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
YL G DLNV AW GYTG G+ + I+DDGI+ HPDLA NY+ AS+D +
Sbjct 131 YLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFS 190
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-VTDAV 235
DP P PRYT N HGTRCAGEV+A ANN +CGVGVAY +++ G+RMLD +TD +
Sbjct 191 SNDPYPYPRYTDDWSNSHGTRCAGEVSAAANNNICGVGVAYGSKVAGIRMLDQPFMTDII 250
Query 236 EARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGN 295
EA S+ P I IYSASWGP D+GKTVDGP L +A GV++GRGG GSI+VWASG+
Sbjct 251 EASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGD 310
Query 296 GGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQN--EKQIVT 353
GG +D CNCDGY +S++T+SI+SA G Y E+CSSTLA+T+S+G + E + T
Sbjct 311 GG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVAT 369
Query 354 TDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN--ANDW 411
TDL CT H+GTSA+AP AAG+ AL LEAN LTWRDMQHL V TSK L+ + W
Sbjct 370 TDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQW 429
Query 412 ATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDI---GKRLEVR 468
NGVG + +H +GYG+LDAGAMV +A++W TV + C+ + P+ I GK + +
Sbjct 430 RRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQNPEKIPTTGKPV-LT 488
Query 469 KTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPH-DYSADG 527
T AC G+ N + LEH QA +T++ RRGDL I++ SPMGT+S LL+ RP D + G
Sbjct 489 LTTDACEGKENFVRYLEHVQAVVTVNATRRGDLNINMTSPMGTKSILLSRRPRGDDAKVG 548
Query 528 FNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGT 573
F+ W FMTTH+W ED G W+LE+ A G L ++TL+L+GT
Sbjct 549 FDKWPFMTTHTWGEDARGTWILELGFVGSAPQKGVLMEWTLMLHGT 594
>sp|P21661|NEC2_MOUSE Neuroendocrine convertase 2 OS=Mus musculus
OX=10090 GN=Pcsk2 PE=1 SV=1
Length=637
Score = 506 bits (1304), Expect = 1e-169, Method: Compositional matrix adjust.
Identities = 284/590 (48%), Positives = 374/590 (63%), Gaps = 30/590 (5%)
Query 9 WVVAATGTLVLLAADAQGQKVFTNTWAVRI-PGGPAVANSVARKHGFLNLGQIFGD-YYH 66
W A V++ A A+ + VFTN + V + G A VA +HGF F + YH
Sbjct 9 WKAAGFLFCVMVFASAE-RPVFTNHFLVELHKDGEEEARQVAAEHGFGVRKLPFAEGLYH 67
Query 67 FWHRGVTK--RSLSPHRPRHSRLQREPQVQWLEQQVA---KRRTKRDVYQ---EPTDPKF 118
F+H G+ K R S H R +L+R+P+++ QQ K+R RD+ + DP F
Sbjct 68 FYHNGLAKAKRRRSLHHKR--QLERDPRIKMALQQEGFDRKKRGYRDINEIDINMNDPLF 125
Query 119 PQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS 172
+QWYL G DLNV AW GYTG G+ + I+DDGI+ HPDLA NY+ AS
Sbjct 126 TKQWYLFNTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLAYNYNADAS 185
Query 173 FDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-V 231
+D + DP P PRYT N HGTRCAGEV+A A+N +CGVGVAYN+++ G+RMLD +
Sbjct 186 YDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAASNNICGVGVAYNSKVAGIRMLDQPFM 245
Query 232 TDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVW 291
TD +EA S+ P I IYSASWGP D+GKTVDGP L +A GV++GRGG GSI+VW
Sbjct 246 TDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVW 305
Query 292 ASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQN--EK 349
ASG+GG +D CNCDGY +S++T+SI+SA G Y E+CSSTLA+T+S+G + E
Sbjct 306 ASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEA 364
Query 350 QIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN-- 407
+ TTDL CT H+GTSA+AP AAG+ AL LEAN +LTWRDMQHL V TSK L+
Sbjct 365 GVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLDLTWRDMQHLTVLTSKRNQLHDE 424
Query 408 ANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDI---GKR 464
+ W NGVG + +H +GYG+LDAGAMV +A++W TV + C+ + P+ I GK
Sbjct 425 VHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQNPEKIPPTGKL 484
Query 465 LEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYS 524
+ KT AC G+ N + LEH QA +T++ RRGDL I++ SPMGT+S LL+ RP D
Sbjct 485 VLTLKT-NACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDD 543
Query 525 AD-GFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGT 573
+ GF+ W FMTTH+W ED G W LE+ A G L ++TL+L+GT
Sbjct 544 SKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGLLKEWTLMLHGT 593
>sp|P28841|NEC2_RAT Neuroendocrine convertase 2 OS=Rattus norvegicus
OX=10116 GN=Pcsk2 PE=1 SV=1
Length=637
Score = 505 bits (1301), Expect = 4e-169, Method: Compositional matrix adjust.
Identities = 283/590 (48%), Positives = 374/590 (63%), Gaps = 30/590 (5%)
Query 9 WVVAATGTLVLLAADAQGQKVFTNTWAVRI-PGGPAVANSVARKHGFLNLGQIFGD-YYH 66
W A V++ A A+ + VFTN + V + G A VA +HGF F + YH
Sbjct 9 WKAAGLLFCVMVFASAE-RPVFTNHFLVELHKDGEEEARQVAAEHGFGVRKLPFAEGLYH 67
Query 67 FWHRGVTK--RSLSPHRPRHSRLQREPQVQWLEQQVA---KRRTKRDVYQ---EPTDPKF 118
F+H G+ K R S H R +L+R+P+++ QQ K+R RD+ + DP F
Sbjct 68 FYHNGLAKAKRRRSLHHKR--QLERDPRIKMALQQEGFDRKKRGYRDINEIDINMNDPLF 125
Query 119 PQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS 172
+QWYL G DLNV AW GYTG G+ + I+DDGI+ HPDLA NY+ AS
Sbjct 126 TKQWYLFNTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLAYNYNSDAS 185
Query 173 FDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-V 231
+D + DP P PRYT N HGTRCAGEV+A A+N +CGVGVAYN+++ G+RMLD +
Sbjct 186 YDFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAASNNICGVGVAYNSKVAGIRMLDQPFM 245
Query 232 TDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVW 291
TD +EA S+ P I IYSASWGP D+GKTVDGP L +A GV++GRGG GSI+VW
Sbjct 246 TDIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVW 305
Query 292 ASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQN--EK 349
ASG+GG +D CNCDGY +S++T+SI+SA G Y E+CSSTLA+T+S+G + E
Sbjct 306 ASGDGG-SYDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEA 364
Query 350 QIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN-- 407
+ TTDL CT H+GTSA+AP AAG+ AL LEAN +LTWRDMQHL V TSK L+
Sbjct 365 GVATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANVDLTWRDMQHLTVLTSKRNQLHDE 424
Query 408 ANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDI---GKR 464
+ W NGVG + +H +GYG+LDAGAMV +A++W TV + C+ + P+ I GK
Sbjct 425 VHQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQNPEKIPPTGKL 484
Query 465 LEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYS 524
+ +T AC G+ N + LEH QA +T++ RRGDL I++ SPMGT+S LL+ RP D
Sbjct 485 VLTLQT-NACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDD 543
Query 525 AD-GFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGT 573
+ GF+ W FMTTH+W ED G W LE+ A G L ++TL+L+GT
Sbjct 544 SKVGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGLLKEWTLMLHGT 593
>sp|P29145|NECB_HYDVU PC3-like endoprotease variant B OS=Hydra
vulgaris OX=6087 PE=2 SV=1
Length=710
Score = 498 bits (1283), Expect = 2e-165, Method: Compositional matrix adjust.
Identities = 262/548 (48%), Positives = 340/548 (62%), Gaps = 17/548 (3%)
Query 30 FTNTWAVRI-PGGPAVANSVARKHGFLNLGQI--FGDYYHFWHRGVTKRSLSPHRPRHSR 86
F+NTWAV I P VA+ +A+KHGF N+G+I +YHF H + +R L R + +
Sbjct 72 FSNTWAVHIDPPDNDVADRIAKKHGFTNIGKIGNIEGHYHFKHEEIGERELEKARHKTAL 131
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL------SGVTQRDLNVKAAWAQ 140
L E +V++ EQQ R KRD P DP F WYL SG D+NV W +
Sbjct 132 LNLEDEVKFAEQQKILERVKRDGI--PNDPYFKDMWYLLNTGQASGPAGVDMNVVPVWKK 189
Query 141 GYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAG 200
TG GIV+S+LDDG++ HPDL NYD AS +ND D DP PR + DN HGTRCAG
Sbjct 190 NITGRGIVISVLDDGLDWTHPDLEANYDQTASIVLNDNDNDPMPRDSDA-DNCHGTRCAG 248
Query 201 EVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDG 260
E AA+ANNG+CG GVAYNA+IGGVRMLDG+ TDA+EA +LG +HI IY WGP+DDG
Sbjct 249 EAAAIANNGICGTGVAYNAKIGGVRMLDGQATDALEASALGFRGDHIDIYINCWGPKDDG 308
Query 261 KTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA 320
KT P +A +A G QGR LGSIFVWA+GNGG D CNCDGYT SI+T+SI
Sbjct 309 KTFGKPGPMAAKALRLGAEQGRNRLGSIFVWATGNGGLTDDDCNCDGYTTSIFTISIGCI 368
Query 321 TQFGNVPWYSEACSSTLATTYSSGNQN---EKQIVTTDLRQKCTESHTGTSASAPLAAGI 377
G +Y+E CSSTLA T++ + E ++VTTDL +CTE GTSASAPLAAGI
Sbjct 369 GDHGLSAYYTEKCSSTLAVTFNGASHKEGRENKMVTTDLYHQCTEEFKGTSASAPLAAGI 428
Query 378 IALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVAL 437
IALTLEAN LTWRD+Q L+V T++ W NG G +H +G+G LDA AMV
Sbjct 429 IALTLEANPLLTWRDVQALIVHTAQITSPVDEGWKRNGAGFHFNHKFGFGRLDANAMVNA 488
Query 438 AQNWTTVAPQRKCIIDILTEPKDI--GKRLEVRKTVTACLGEPNHITRLEHAQARLTLSY 495
AQ+W + QRKC + +DI G L + AC I ++EH ++ +
Sbjct 489 AQSWKNLPAQRKCTAASGFDHQDIPRGDSLFINIPTVACESSSAQIAKVEHVVLTVSFVH 548
Query 496 NRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS 555
RRGD++I L+SP T+S +L+ R +D S +G ++W+FMT ++W E+P G W L+I +
Sbjct 549 RRRGDVSIDLISPKDTKSQMLSPRKYDDSDEGLDEWSFMTVYNWGENPKGIWRLKITDNP 608
Query 556 EANNYGTL 563
++ L
Sbjct 609 NQDDVMNL 616
>sp|P29146|NECA_HYDVU PC3-like endoprotease variant A OS=Hydra
vulgaris OX=6087 PE=2 SV=1
Length=793
Score = 499 bits (1285), Expect = 1e-164, Method: Compositional matrix adjust.
Identities = 261/536 (49%), Positives = 336/536 (63%), Gaps = 17/536 (3%)
Query 30 FTNTWAVRI-PGGPAVANSVARKHGFLNLGQI--FGDYYHFWHRGVTKRSLSPHRPRHSR 86
F+NTWAV I P VA+ +A+KHGF N+G+I +YHF H + +R L R + +
Sbjct 72 FSNTWAVHIDPPDNDVADRIAKKHGFTNIGKIGNIEGHYHFKHEEIGERELEKARHKTAL 131
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL------SGVTQRDLNVKAAWAQ 140
L E +V++ EQQ R KRD P DP F WYL SG D+NV W +
Sbjct 132 LNLEDEVKFAEQQKILERVKRDGI--PNDPYFKDMWYLLNTGQASGPAGVDMNVVPVWKK 189
Query 141 GYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAG 200
TG GIV+S+LDDG++ HPDL NYD AS +ND D DP PR + DN HGTRCAG
Sbjct 190 NITGRGIVISVLDDGLDWTHPDLEANYDQTASIVLNDNDNDPMPRDSDA-DNCHGTRCAG 248
Query 201 EVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDG 260
E AA+ANNG+CG GVAYNA+IGGVRMLDG+ TDA+EA +LG +HI IY WGP+DDG
Sbjct 249 EAAAIANNGICGTGVAYNAKIGGVRMLDGQATDALEASALGFRGDHIDIYINCWGPKDDG 308
Query 261 KTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA 320
KT P +A +A G QGR LGSIFVWA+GNGG D CNCDGYT SI+T+SI
Sbjct 309 KTFGKPGPMAAKALRLGAEQGRNRLGSIFVWATGNGGLTDDDCNCDGYTTSIFTISIGCI 368
Query 321 TQFGNVPWYSEACSSTLATTYSSGNQN---EKQIVTTDLRQKCTESHTGTSASAPLAAGI 377
G +Y+E CSSTLA T++ + E ++VTTDL +CTE GTSASAPLAAGI
Sbjct 369 GDHGLSAYYTEKCSSTLAVTFNGASHKEGRENKMVTTDLYHQCTEEFKGTSASAPLAAGI 428
Query 378 IALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVAL 437
IALTLEAN LTWRD+Q L+V T++ W NG G +H +G+G LDA AMV
Sbjct 429 IALTLEANPLLTWRDVQALIVHTAQITSPVDEGWKRNGAGFHFNHKFGFGRLDANAMVNA 488
Query 438 AQNWTTVAPQRKCIIDILTEPKDI--GKRLEVRKTVTACLGEPNHITRLEHAQARLTLSY 495
AQ+W + QRKC + +DI G L + AC I ++EH ++ +
Sbjct 489 AQSWKNLPAQRKCTAASGFDHQDIPRGDSLFINIPTVACESSSAQIAKVEHVVLTVSFVH 548
Query 496 NRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEI 551
RRGD++I L+SP T+S +L+ R +D S +G ++W+FMT ++W E+P G W L+I
Sbjct 549 RRRGDVSIDLISPKDTKSQMLSPRKYDDSDEGLDEWSFMTVYNWGENPKGIWRLKI 604
>sp|G5ECN9|NEC2_CAEEL Neuroendocrine convertase 2 OS=Caenorhabditis
elegans OX=6239 GN=egl-3 PE=1 SV=1
Length=652
Score = 493 bits (1269), Expect = 4e-164, Method: Compositional matrix adjust.
Identities = 274/634 (43%), Positives = 368/634 (58%), Gaps = 57/634 (9%)
Query 17 LVLLAADAQGQKVFTNTWAVRIP--GGPAVANSVARKHGFLNLGQIFG--DYYHFWHRGV 72
L + + V+TN + V + GG A+ +A++HGF+N GQ+ + YHF +
Sbjct 13 LSIFIGIGEAVDVYTNHFHVHLKEGGGLEDAHRIAKRHGFINRGQVAASDNEYHFVQPAL 72
Query 73 TKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKR---------------DVYQEPTDPK 117
H++L + +V +EQ RTKR P+DP
Sbjct 73 VHARTRRSAGHHAKLHNDDEVLHVEQLKGYTRTKRGYRPLEQRLESQFDFSAVMSPSDPL 132
Query 118 FPQQWYLS------GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGA 171
+ QWYL G + DLNV+ AWA G+TG I +I+DDG++ HPD+ N++ A
Sbjct 133 YGYQWYLKNTGQAGGKARLDLNVERAWAMGFTGKNITTAIMDDGVDYMHPDIKNNFNAEA 192
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG-E 230
S+D + DP P PRYT N HGTRCAGE+ A +NGVCGVGVAY+ ++ G+RMLD
Sbjct 193 SYDFSSNDPFPYPRYTDDWFNSHGTRCAGEIVAARDNGVCGVGVAYDGKVAGIRMLDQPY 252
Query 231 VTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFV 290
+TD +EA S+G P+ IHIYSASWGP DDGKTVDGP A RGV++GR GLGSIFV
Sbjct 253 MTDLIEANSMGHEPSKIHIYSASWGPTDDGKTVDGPRNATMRAIVRGVNEGRNGLGSIFV 312
Query 291 WASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQN-EK 349
WASG+GG E D CNCDGY S++T+SI+SA G Y E+CSSTLA+T+S+G +N E
Sbjct 313 WASGDGG-EDDDCNCDGYAASMWTISINSAINNGENAHYDESCSSTLASTFSNGGRNPET 371
Query 350 QIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTS-------- 401
+ TTDL +CT SH+GTSA+AP AAG+ AL LEAN +LTWRD+QHL V TS
Sbjct 372 GVATTDLYGRCTRSHSGTSAAAPEAAGVFALALEANPSLTWRDLQHLTVLTSSRNSLFDG 431
Query 402 --------------KPAHLNAN--DWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVA 445
+ +H N + +W NGVG + +H +G+G+LDA MV LA W T
Sbjct 432 RCRDFPSLGINDNHRDSHGNCSHFEWQMNGVGLEYNHLFGFGVLDAAEMVMLAMAWKTSP 491
Query 446 PQRKCIIDILTEPKDI--GKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAI 503
P+ C ++ P +I L + C G + LEH QA ++ + RRGD +
Sbjct 492 PRYHCTAGLIDTPHEIPADGNLILEINTDGCAGSQFEVRYLEHVQAVVSFNSTRRGDTTL 551
Query 504 HLVSPMGTRSTLLAARPH-DYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGT 562
+L+SPMGTR+ +L+ RP D S DGF +W FMTTH+W E+P+G+W L + GT
Sbjct 552 YLISPMGTRTMILSRRPKDDDSKDGFTNWPFMTTHTWGENPTGKWRLVARFQGPGAHAGT 611
Query 563 LTKFTLVLYGT--APEGLPVPPESSGCKTLTSSQ 594
L KF L+L+GT AP L P K L + Q
Sbjct 612 LKKFELMLHGTREAPYNLIEPIVGQTNKKLDTVQ 645
>sp|Q62849|PCSK7_RAT Proprotein convertase subtilisin/kexin type
7 OS=Rattus norvegicus OX=10116 GN=Pcsk7 PE=1 SV=1
Length=783
Score = 400 bits (1027), Expect = 2e-126, Method: Compositional matrix adjust.
Identities = 250/611 (41%), Positives = 345/611 (56%), Gaps = 29/611 (5%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQ--RDLNVKAAWAQGYTG 144
L + V+W +Q +R KR ++ DPK+PQQW+L+ RD+NV W + TG
Sbjct 120 LAKHEAVRWHSEQRLLKRAKRSIHF--NDPKYPQQWHLNNRRSPGRDINVTGVWERNVTG 177
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G+ V ++DDG+E D+A NY P S+D+N DPDP P + N N HGTRCAGE+AA
Sbjct 178 RGVTVVVVDDGVEHTVQDIAPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAA 237
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVD 264
V NN C VGVAY +RI G+R+LDG +TD++EA + + IYS SWGP+DDGKTVD
Sbjct 238 VPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVD 297
Query 265 GPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFG 324
GP +L + A GV GR G GSIFV ASGNGG+ +D+CN DGY NSIYT++I + + G
Sbjct 298 GPHQLGKAALQHGVMAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEG 357
Query 325 NVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQK----CTESHTGTSASAPLAAGIIAL 380
+P+Y+E C+S LA T+S G++ + IVTTD + CTE HTGTSA+APLAAG+IAL
Sbjct 358 RMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIAL 417
Query 381 TLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQN 440
L+ LTWRD+QH++V T+ + DW TN G SH +G+GLL+A +V A+
Sbjct 418 MLQVRPCLTWRDVQHIIVFTATQYEDHRADWLTNEAGFSHSHQHGFGLLNAWRLVNAAKI 477
Query 441 WTTVAPQRKCIIDILTEPKDIGK---RLEVRKTVTACLGEPNHITRLEHAQARLTLSYNR 497
WT+V + +L E K + + LEV V+ E + + LEH +++++ R
Sbjct 478 WTSVPYLASYVSPMLKENKAVPRSPHSLEVLWNVSRTDLEMSGLKTLEHVAVTVSITHPR 537
Query 498 RGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENT-SE 556
RG L + L P G S + A R D +GFNDW F T W E G + L I + E
Sbjct 538 RGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGVYRLVIRDVGDE 597
Query 557 ANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPP 616
G L ++ L LYG+ + + S L S+ + + F+L CPP
Sbjct 598 PLQVGILQQWQLTLYGSTWSPVDIKDRQS---LLESAMSGKYLHDDFTL-------PCPP 647
Query 617 GFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCS 676
G D + T N ++T+ V C + T L CLS S AS + C
Sbjct 648 GLKIPEEDGYSITPNTLKTL---VLVGCFSVFWTIY-YMLEVCLSQRSKASTHGCRRGCC 703
Query 677 ---RQSQSSRE 684
QSQ+S+E
Sbjct 704 PWPPQSQNSKE 714
>sp|Q61139|PCSK7_MOUSE Proprotein convertase subtilisin/kexin
type 7 OS=Mus musculus OX=10090 GN=Pcsk7 PE=2 SV=2
Length=770
Score = 397 bits (1021), Expect = 1e-125, Method: Compositional matrix adjust.
Identities = 236/565 (42%), Positives = 326/565 (58%), Gaps = 22/565 (4%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQ--RDLNVKAAWAQGYTG 144
L R V+W +Q +R KR ++ DPK+PQQW+L+ RD+NV W + TG
Sbjct 120 LARHEAVRWHSEQTLLKRAKRSIHF--NDPKYPQQWHLNNRRSPGRDINVTGVWERNVTG 177
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G+ V ++DDG+E D+A NY P S+D+N DPDP P + N N HGTRCAGE+AA
Sbjct 178 RGVTVVVVDDGVEHTVQDIAPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAA 237
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVD 264
V NN C VGVAY +RI G+R+LDG +TD++EA + + IYS SWGP+DDGKTVD
Sbjct 238 VPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVD 297
Query 265 GPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFG 324
GP +L + A GV GR G GSIFV ASGNGG+ +D+CN DGY NSIYT++I + + G
Sbjct 298 GPHQLGKAALQHGVMAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEG 357
Query 325 NVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQK----CTESHTGTSASAPLAAGIIAL 380
+P+Y+E C+S LA T+S G++ + IVTTD + CTE HTGTSA+APLAAG+IAL
Sbjct 358 RMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIAL 417
Query 381 TLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQN 440
L+ LTWRD+QH++V T+ + DW TN G SH +G+GLL+A +V A+
Sbjct 418 MLQVRPCLTWRDVQHIIVFTAIQYEDHHADWLTNEAGFSHSHQHGFGLLNAWRLVNAAKI 477
Query 441 WTTVAPQRKCIIDILTEPKDIGK---RLEVRKTVTACLGEPNHITRLEHAQARLTLSYNR 497
WT+V + +L E K + + LEV V+ E + + LEH +++++ R
Sbjct 478 WTSVPYLASYVSPMLKENKAVPRSPHSLEVLWNVSRTDLEMSGLKTLEHVAVTVSITHPR 537
Query 498 RGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENT-SE 556
RG L + L P G S + A R D +GFN W F T W E G + L I + E
Sbjct 538 RGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNAWTFSTVRCWGERARGVYRLVIRDVGDE 597
Query 557 ANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPP 616
G L ++ L LYG+ + + S L S+ + +GF+L CPP
Sbjct 598 PLQMGILQQWQLTLYGSMWSPVDIKDRQS---LLESAMSGKYLHDGFTL-------PCPP 647
Query 617 GFAPQVLDTHYSTENDVETIRASVC 641
G D + T N ++T+ C
Sbjct 648 GLKIPEEDGYTITPNTLKTLVLVGC 672
>sp|Q16549|PCSK7_HUMAN Proprotein convertase subtilisin/kexin
type 7 OS=Homo sapiens OX=9606 GN=PCSK7 PE=1 SV=2
Length=785
Score = 395 bits (1016), Expect = 6e-125, Method: Compositional matrix adjust.
Identities = 235/559 (42%), Positives = 323/559 (58%), Gaps = 22/559 (4%)
Query 93 VQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQ--RDLNVKAAWAQGYTGHGIVVS 150
V+W +Q RR KR V+ DPK+PQQW+L+ RD+NV W + TG G+ V
Sbjct 127 VRWHSEQRLLRRAKRSVHF--NDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVV 184
Query 151 ILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGV 210
++DDG+E D+A NY P S+D+N DPDP P N N HGTRCAGE+AAV NN
Sbjct 185 VVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSF 244
Query 211 CGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLA 270
C VGVAY +RI G+R+LDG +TD++EA + + IYS SWGP+DDGKTVDGP +L
Sbjct 245 CAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLG 304
Query 271 EEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYS 330
+ A GV GR G GSIFV ASGNGG+ +D+CN DGY NSIYT++I + + G +P+Y+
Sbjct 305 KAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYA 364
Query 331 EACSSTLATTYSSGNQNEKQIVTTDLRQK----CTESHTGTSASAPLAAGIIALTLEANK 386
E C+S LA T+S G++ + IVTTD + CTE HTGTSA+APLAAG+IAL L+
Sbjct 365 EECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRP 424
Query 387 NLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAP 446
LTWRD+QH++V T+ +W TN G SH +G+GLL+A +V A+ WT+V
Sbjct 425 CLTWRDVQHIIVFTATRYEDRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPY 484
Query 447 QRKCIIDILTEPKDI---GKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAI 503
+ +L E K I + LEV V+ E + + LEH +++++ RRG L +
Sbjct 485 LASYVSPVLKENKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLEL 544
Query 504 HLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENT-SEANNYGT 562
L P G S + A R D +GFNDW F T W E G + L I + E+ G
Sbjct 545 KLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRLVIRDVGDESFQVGI 604
Query 563 LTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQV 622
L ++ L LYG+ + + + L S+ + + F+L CPPG
Sbjct 605 LRQWQLTLYGSVWSAVDIRDRQ---RLLESAMSGKYLHDDFAL-------PCPPGLKIPE 654
Query 623 LDTHYSTENDVETIRASVC 641
D + T N ++T+ C
Sbjct 655 EDGYTITPNTLKTLVLVGC 673
>sp|Q09175|KRP1_SCHPO Dibasic-processing endoprotease OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=krp1
PE=1 SV=1
Length=709
Score = 385 bits (990), Expect = 7e-122, Method: Compositional matrix adjust.
Identities = 208/500 (42%), Positives = 284/500 (57%), Gaps = 29/500 (6%)
Query 96 LEQQVAKRRTKRDVYQEP------------TDPKFPQQWYL--SGVTQRDLNVKAAWAQG 141
LE+Q + R KRD + +DP F QW++ S DLN++ W G
Sbjct 91 LERQTPRWRYKRDASESDELLNEFSNHFGISDPLFYGQWHIFNSNNPGHDLNLREVWDAG 150
Query 142 YTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGE 201
Y G + V+ +DDGI+ HPDL Y S+D ND DP P+ ++D++HGTRCAGE
Sbjct 151 YFGENVTVAFVDDGIDFKHPDLQAAYTSLGSWDFNDNIADPLPK---LSDDQHGTRCAGE 207
Query 202 VAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGK 261
VAA A N VCGVG+A A++ G+R+L +TDAVE+ +L HIYS SWGP DDG+
Sbjct 208 VAA-AWNDVCGVGIAPRAKVAGLRILSAPITDAVESEALNYGFQTNHIYSCSWGPADDGR 266
Query 262 TVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
+D P A GV GR GLGSIFV+ASGNGG HD+CN DGYTNSI++ +I +
Sbjct 267 AMDAPNTATRRALMNGVLNGRNGLGSIFVFASGNGGHYHDNCNFDGYTNSIFSATIGAVD 326
Query 322 QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALT 381
+P+YSE C++ L + YSSG+ I+TT+ CT SH GTSA+APLA+ + AL
Sbjct 327 AEHKIPFYSEVCAAQLVSAYSSGSH--LSILTTNPEGTCTRSHGGTSAAAPLASAVYALA 384
Query 382 LEANKNLTWRDMQHLVVQTSKPAHLNAN--DWATNGVGRKVSHSYGYGLLDAGAMVALAQ 439
L +L+WRD+QH+ V ++ P + +W G + SH +G+G LDA V +A+
Sbjct 385 LSIRPDLSWRDIQHITVYSASPFDSPSQNAEWQKTPAGFQFSHHFGFGKLDASKFVEVAK 444
Query 440 NWTTVAPQRKCIIDILTEPKDIGK-------RLEVRKTVTACLGEPNHITRLEHAQARLT 492
+W V PQ I + K G + TVT + E ++ RLEH R+
Sbjct 445 DWQVVNPQTWLIAPEINVNKSFGSVNNETITEMVSEFTVTKDMIEKSNFKRLEHVTVRVC 504
Query 493 LSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIE 552
+ +NRRG L I L SP G RS L + RP+D ++ GF DW FMT W E P G W L +
Sbjct 505 IPFNRRGALEILLESPSGIRSILASERPYDENSKGFLDWTFMTVQHWAEPPEGVWKLLVN 564
Query 553 NTSEANNYGTLTKFTLVLYG 572
+ S + GT + L L+G
Sbjct 565 DRSGGKHEGTFENWQLALWG 584
>sp|P09231|KEX1A_KLULA Protease KEX1 OS=Kluyveromyces lactis (strain
ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140
/ WM37) OX=284590 GN=KEX1 PE=3 SV=2
Length=756
Score = 375 bits (964), Expect = 2e-117, Method: Compositional matrix adjust.
Identities = 198/466 (42%), Positives = 291/466 (62%), Gaps = 16/466 (3%)
Query 114 TDPKFPQQWYLSGVTQ--RDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGA 171
+DP F QQW+L D+NV W + TG+G+V +++DDG++ + DL N+
Sbjct 123 SDPLFDQQWHLINPNYPGNDVNVTGLWKENITGYGVVAALVDDGLDYENEDLKDNFCVEG 182
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEV 231
S+D ND +P P+PR + D+ HGTRCAGE+AA N+ +CGVGVAYN+++ G+R+L G++
Sbjct 183 SWDFNDNNPLPKPR---LKDDYHGTRCAGEIAAFRND-ICGVGVAYNSKVSGIRILSGQI 238
Query 232 TDAVEARSL--GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIF 289
T EA SL GL+ N I YS SWGP DDGKT+ P L ++A +GV++GR G+++
Sbjct 239 TAEDEAASLIYGLDVNDI--YSCSWGPSDDGKTMQAPDTLVKKAIIKGVTEGRDAKGALY 296
Query 290 VWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEK 349
V+ASGNGG DSCN DGYTNSI+++++ + G P YSE+CS+ + TYSSG+ N
Sbjct 297 VFASGNGGMFGDSCNFDGYTNSIFSITVGAIDWKGLHPPYSESCSAVMVVTYSSGSGN-- 354
Query 350 QIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAN 409
I TTDL +KC+ +H GTSA+APLAAGI L LEAN NLTWRD+Q+L + +S+ + +
Sbjct 355 YIKTTDLDEKCSNTHGGTSAAAPLAAGIYTLVLEANPNLTWRDVQYLSILSSEEINPHDG 414
Query 410 DWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRK 469
W +G++ SH+YG+G LDA +V +A++W V PQ + + E + I EV +
Sbjct 415 KWQDTAMGKRYSHTYGFGKLDAYNIVHMAKSWINVNPQGWLYLPTIVEKQSISNSDEVIE 474
Query 470 TVTACLGEP---NHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD 526
+ + E N++ RLEH + + RG + + L+SP G STL AR D +
Sbjct 475 STVSVSAEEFKQNNLKRLEHVTVTVDIDAPYRGHVLVDLISPDGVTSTLATARRLDKNRY 534
Query 527 GFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYG 572
GF +W FM+ W G W L++++T + N TL + L ++G
Sbjct 535 GFQNWTFMSVAHWGSSGVGSWKLKVKSTHD-NEIVTLKSWRLKMFG 579
>sp|P13134|KEX2_YEAST Kexin OS=Saccharomyces cerevisiae (strain
ATCC 204508 / S288c) OX=559292 GN=KEX2 PE=1 SV=1
Length=814
Score = 353 bits (905), Expect = 3e-108, Method: Compositional matrix adjust.
Identities = 190/466 (41%), Positives = 281/466 (60%), Gaps = 16/466 (3%)
Query 115 DPKFPQQWYLSGVT--QRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS 172
DP F +QW+L + D+NV W TG G+V +I+DDG++ + DL N+ S
Sbjct 135 DPLFERQWHLVNPSFPGSDINVLDLWYNNITGAGVVAAIVDDGLDYENEDLKDNFCAEGS 194
Query 173 FDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVT 232
+D ND P+PR ++D+ HGTRCAGE+AA N CGVGV YNA+I G+R+L G++T
Sbjct 195 WDFNDNTNLPKPR---LSDDYHGTRCAGEIAAKKGNNFCGVGVGYNAKISGIRILSGDIT 251
Query 233 DAVEARSL--GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFV 290
EA SL GL+ N IYS SWGP DDG+ + GP+ L ++A +GV++GR G+I+V
Sbjct 252 TEDEAASLIYGLDVN--DIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYV 309
Query 291 WASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQ 350
+ASGNGG D+CN DGYTNSIY+++I + P YSE CS+ +A TYSSG+ +
Sbjct 310 FASGNGGTRGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTYSSGSG--EY 367
Query 351 IVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAN- 409
I ++D+ +C+ SH GTSA+APLAAG+ L LEAN NLTWRD+Q+L + ++ NA+
Sbjct 368 IHSSDINGRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVGLEKNADG 427
Query 410 DWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIG---KRLE 466
DW + +G+K SH YG+G +DA ++ +++ W V Q + L + + LE
Sbjct 428 DWRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLPTLYVSQSTNSTEETLE 487
Query 467 VRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD 526
T++ + + R+EH + + RG + L+SP G S L RP D S++
Sbjct 488 SVITISEKSLQDANFKRIEHVTVTVDIDTEIRGTTTVDLISPAGIISNLGVVRPRDVSSE 547
Query 527 GFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYG 572
GF DW FM+ W E+ G+W ++++ T+E + + L L+G
Sbjct 548 GFKDWTFMSVAHWGENGVGDWKIKVK-TTENGHRIDFHSWRLKLFG 592
>sp|O13359|KEX2_CANAW Kexin OS=Candida albicans (strain WO-1)
OX=294748 GN=KEX2 PE=3 SV=2
Length=938
Score = 349 bits (896), Expect = 7e-106, Method: Compositional matrix adjust.
Identities = 187/473 (40%), Positives = 280/473 (59%), Gaps = 31/473 (7%)
Query 98 QQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQ--RDLNVKAAWAQGYTGHGIVVSILDDG 155
Q++ + K D++ DP+F QW+L + D+NV W + G GIV +++DDG
Sbjct 160 QKLIEIAKKLDIH----DPEFTTQWHLINLKYPGHDVNVTGLWLENILGQGIVTALVDDG 215
Query 156 IEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGV 215
++ D+ N++ S+D N++ P PR + D+ HGTRCAGE+AAV N+ VCG+GV
Sbjct 216 VDAESDDIKQNFNSEGSWDFNNKGKSPLPR---LFDDYHGTRCAGEIAAVKND-VCGIGV 271
Query 216 AYNARIGGVRMLDGEVT--DAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEA 273
A+ +++ G+R+L G +T D EA GL+ N I YS SWGP D+GK + P + ++A
Sbjct 272 AWKSQVSGIRILSGPITSSDEAEAMVYGLDTNDI--YSCSWGPTDNGKVLSEPDVIVKKA 329
Query 274 FFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEAC 333
+G+ +GR G+I+V+ASGNGGR DSCN DGYTNSIY++++ + G P YSEAC
Sbjct 330 MIKGIQEGRDKKGAIYVFASGNGGRFGDSCNFDGYTNSIYSITVGAIDYKGLHPQYSEAC 389
Query 334 SSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDM 393
S+ + TYSSG+ + I TTD+++KC+ +H GTSA+APLA+GI +L L AN NLTWRD+
Sbjct 390 SAVMVVTYSSGSG--EHIHTTDIKKKCSATHGGTSAAAPLASGIYSLILSANPNLTWRDV 447
Query 394 QHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIID 453
Q++ V ++ P + ++ T + RK SH YGYG DA MV A+ W V PQ D
Sbjct 448 QYISVLSATPINEEDGNYQTTALNRKYSHKYGYGKTDAYKMVHFAKTWVNVKPQAWYYSD 507
Query 454 ILT---------EPKDIGKRLEVRKTVTACLG------EPNHITRLEHAQARLTLSYNRR 498
I+ E K KR +K + + + + ++ R+EH ++ + R
Sbjct 508 IIEVNQTITTTPEQKAPSKRDSPQKIIHSSVNVSEKDLKIMNVERVEHITVKVNIDSTYR 567
Query 499 GDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEI 551
G + + ++SP G S L R +D S GF +W FM+ W E GEW +E+
Sbjct 568 GRVGMRIISPTGVISDLATFRVNDASTRGFQNWTFMSVAHWGETGIGEWKVEV 620
>sp|P42781|XPR6_YARLI Dibasic-processing endoprotease OS=Yarrowia
lipolytica (strain CLIB 122 / E 150) OX=284591 GN=XPR6 PE=3
SV=1
Length=976
Score = 349 bits (896), Expect = 2e-105, Method: Compositional matrix adjust.
Identities = 184/470 (39%), Positives = 274/470 (58%), Gaps = 19/470 (4%)
Query 115 DPKFPQQWYLSGVTQ--RDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS 172
DP +QWYL V + DLNV W + TG G+V +++DDG++ N D+ NY S
Sbjct 271 DPSLWKQWYLHNVHKAGHDLNVTGLWLRNVTGWGVVTAVVDDGLDMNAEDIKANYFAEGS 330
Query 173 FDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVT 232
+D N DP+P +D+ HGTRCAGE+AAV NN VCGVGVAY++++ G+R+L E+
Sbjct 331 WDFNFNKSDPKP---SSHDDYHGTRCAGEIAAVRNN-VCGVGVAYDSKVAGIRILSKEIA 386
Query 233 DAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWA 292
+ +EA ++ + IYS SWGP D+G+T+ P ++ ++A ++ GR G G++FV+A
Sbjct 387 EDIEALAINYEMDKNDIYSCSWGPPDNGQTMARPGKVVKDAMVNAITNGRQGKGNVFVFA 446
Query 293 SGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIV 352
SGNGG D+CN DGYTNSIY++++ + P+YSEACS+ + TYSSG +E IV
Sbjct 447 SGNGGSRGDNCNFDGYTNSIYSITVGALDFNDGHPYYSEACSANMVVTYSSG--SEHYIV 504
Query 353 TTDLRQ--------KCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPA 404
TD+ +C H GTSA+APLAAG+ AL L +LTWRDMQ+L + ++
Sbjct 505 GTDINAIDDKSAAPRCQNQHGGTSAAAPLAAGVFALALSVRPDLTWRDMQYLALYSAVEI 564
Query 405 HLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKR 464
+ N + W G++ H +GYG LDA +V LA+ W V Q ++ T + +
Sbjct 565 NSNDDGWQDTASGQRFHHQFGYGKLDASKIVELAEGWNLVNNQTSFHSEVKTVSQKVKYN 624
Query 465 LEVRKTVTACLGEPNHIT--RLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHD 522
++ +T + + + R EH A L L + RG + + L P G S L A R D
Sbjct 625 EPLKSVITVTRDDLDKVNFKRAEHITAVLNLEASYRGHVRVLLKGPRGVVSELAALRRDD 684
Query 523 YSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYG 572
S DG+++WAFM+ W ++ G+W L +ENT E + L + L ++G
Sbjct 685 RSKDGYDNWAFMSVAHWADEGEGDWELTVENTGEQDQV-ELVNWQLNVFG 733
>sp|P91863|AEX5_CAEEL Endoprotease aex-5 OS=Caenorhabditis elegans
OX=6239 GN=aex-5 PE=1 SV=2
Length=537
Score = 239 bits (609), Expect = 1e-68, Method: Compositional matrix adjust.
Identities = 169/478 (35%), Positives = 247/478 (52%), Gaps = 37/478 (8%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQ-WYLSGVTQRDLNVKAAWAQGYT 143
+ + QVQ++E+ RR KR T+ +P W L+ L ++ AW G+
Sbjct 77 AEMMLSQQVQFIEKLQGFRRYKR---APMTNKGYPVHVWNLT----PSLYIREAWEDGFN 129
Query 144 GHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVA 203
+ V+++DDG++ H DL + P SFD P P+ ++ + HGT+CAG VA
Sbjct 130 ASRVTVAVVDDGVDIKHVDLKSAFSPRVSFDFVRFGDLPTPKNSK--EFEHGTQCAGLVA 187
Query 204 AVANNGVCGVGVAYNARIGGVRMLDGE-VTDAVEARSLGLNPNHIHIYSASWGPEDDGKT 262
CG+GV + A +G +++L + + DA+E +L + I IYS SWGP+DDGK+
Sbjct 188 MEGQQ--CGLGVGHGATLGAIKLLGQDFLNDALEGDALAFQKDLIDIYSVSWGPKDDGKS 245
Query 263 VDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQ 322
+ PA+ EEA G GR G G+IFVWASGNGG D+C DGY ++ YTLS
Sbjct 246 AEKPAKFTEEAIKNGALHGRNGKGNIFVWASGNGGVNGDNCAYDGYVSNEYTLSFGVIDA 305
Query 323 FGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTL 382
G Y E CSS LA S G + I TT L + S +G+SASA +A+GII+L L
Sbjct 306 SGAPAAYGEGCSSVLAAV-SGG---DAMIQTTGL-ESTCSSISGSSASAAIASGIISLVL 360
Query 383 EANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWT 442
+AN L+ RD+QHL+ +TS + + + N G G+GLL+A +V +A W
Sbjct 361 DANPTLSQRDIQHLIARTSNASAIRDVELYENSAGLNFHPKVGFGLLNAQKLVVMAATWE 420
Query 443 TVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPN-HITRLEHAQARLTLSYNRRGDL 501
VAPQ C E + + +T++E ++ + RG +
Sbjct 421 NVAPQVTC---------------EKMNLANGIIDNSDCDVTKVERVIVSGSIIHPHRGQV 465
Query 502 AIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANN 559
I L SP GT S LL RP D S D DW F++ + + E+ G W L + TSE ++
Sbjct 466 QIRLESPRGTISELLPLRPKDTSRD-LLDWNFVSVNFFGENSRGIWKLHV--TSEEDD 520
>sp|P23916|PRCA_TRIV2 Calcium-dependent protease OS=Trichormus
variabilis (strain ATCC 29413 / PCC 7937) OX=240292 GN=prcA
PE=1 SV=3
Length=662
Score = 113 bits (282), Expect = 1e-24, Method: Compositional matrix adjust.
Identities = 133/538 (25%), Positives = 216/538 (40%), Gaps = 99/538 (18%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVT------QRDLNVKAAWA 139
RL E V+ ++ + +R FP QW+L T NV+AAW
Sbjct 169 RLLNEESVELCHPELVREFRQRQA--------FPPQWHLKQTTIGGKTINAHANVEAAWK 220
Query 140 QGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
G G +++I+DDG++ +H + + A DV + P P N + HGT CA
Sbjct 221 LS-DGTGTIIAIIDDGVDIDHEEFRSSGKIVAPRDVTRKTNFPTPG----NRDNHGTACA 275
Query 200 GEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPED- 258
G A N GVA A++ +R + + + N + S SWGP D
Sbjct 276 G--VACGNGNFGASGVAPGAKLMPIRFVSALGSQDEADSFVWAAQNGADVISCSWGPPDG 333
Query 259 ---DGKT--------VDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDG 307
D K + RLA + +++GR G G + ++A+GNG ++S + DG
Sbjct 334 TWWDDKDPLHKQKVPLPDSTRLAMD---YAINKGRNGKGCVILFAAGNG---NESVDNDG 387
Query 308 YTNSIYTLSISSATQFGNVPWYSE-----------------------ACSSTLATTYSSG 344
Y + +++++ FG YS+ T Y+SG
Sbjct 388 YASYEKVIAVAACNDFGTRSAYSDFGTAVWCAFPSNNGNPSQTPGIWTADRTGVVGYNSG 447
Query 345 NQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPA 404
N N D T S GTS++ P AAG+ AL L N NL W +++ ++ ++
Sbjct 448 NTN-----LGDQAGNYTNSFGGTSSACPGAAGVAALILSRNPNLRWDEVRDIIKRSCDRI 502
Query 405 HLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKR 464
++ N GR S YGYG ++A V LA P + + I T +D+
Sbjct 503 DPVGGNY--NAEGR--SPFYGYGRINALKAVELA------LPAQPEPVSIFTAVQDVPIN 552
Query 465 LEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYS 524
++ + N I + + + + + GDL + L P S +L HD
Sbjct 553 DLQISQLSLAIANTNPIKSI---KVTVDIEHTYIGDLVVSLNPP--AESGVLPIILHDRK 607
Query 525 ADGFNDWAFMTTHSWDE------------DPSGEWVLEIENTSEANNYGTLTKFTLVL 570
G +D ++DE P G W LE+ + ++A+ G + T+ L
Sbjct 608 GGGADD----IKQTYDEVSTPGLTALKGKIPQGTWTLEVADKAQADT-GKIRSLTIEL 660
>sp|Q59149|PRCA_NOSS1 Calcium-dependent protease OS=Nostoc sp.
(strain PCC 7120 / SAG 25.82 / UTEX 2576) OX=103690 GN=prcA
PE=3 SV=2
Length=662
Score = 108 bits (270), Expect = 4e-23, Method: Compositional matrix adjust.
Identities = 131/534 (25%), Positives = 219/534 (41%), Gaps = 91/534 (17%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVT------QRDLNVKAAWA 139
RL E V+ ++ + +R F QQW+L T + NV+AAW
Sbjct 169 RLLNEESVELCHPELVREFRQRQA--------FSQQWHLKETTIGGKTIKAHANVEAAWK 220
Query 140 QGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
G G +++I+DDG++ +H + + A DV + P P N + HGT CA
Sbjct 221 LS-DGTGTIIAIIDDGVDVDHEEFRSSGKIVAPRDVTRKTNFPTPG----NRDNHGTACA 275
Query 200 GEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPED- 258
G A N GVA A++ +R + + + N + S SWGP D
Sbjct 276 G--VACGNGNFGASGVAPGAKLMPIRFVSALGSQDEADSFVWAAQNGADVISCSWGPPDG 333
Query 259 ---DGKT--------VDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDG 307
D K + RLA + +++GR G G + ++A+GNG ++S + DG
Sbjct 334 TWWDDKDPLHKQKVPLPDSTRLAMD---YAINKGRNGKGCVILFAAGNG---NESVDNDG 387
Query 308 YTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIV--------------- 352
Y + +++++ FG YS+ + + S N N Q
Sbjct 388 YASYEKVIAVAACNDFGTRSAYSD-FGQAVWCAFPSNNGNPSQTPGIWTADRSGVVGYNS 446
Query 353 -TTDLRQKC---TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA 408
+T+L + T S GTS++ P AAG+ AL L N NL W +++ ++ ++
Sbjct 447 GSTNLGDQAGNYTNSFGGTSSACPGAAGVAALILSRNPNLRWDEVRDIIKRSCDRIDPVG 506
Query 409 NDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVR 468
++ N GR S YGYG ++A V LA P + + I T +D+
Sbjct 507 GNY--NAEGR--SPFYGYGRINALKAVELA------LPAQPEPVSIFTAVQDVPINDLQT 556
Query 469 KTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGF 528
++ + N I + + + + + GDL + L P +L HD G
Sbjct 557 SQLSLAIANTNPIKSI---KVTVDIEHTYIGDLIVSLNPP--GECGVLPIILHDRKGGGA 611
Query 529 NDWAFMTTHSWDE------------DPSGEWVLEIENTSEANNYGTLTKFTLVL 570
+D ++DE P G W LE+ + ++A+ G + T+ L
Sbjct 612 DD----IKQTYDEVSTPGLTALKGKIPQGTWTLEVADKAQADT-GKIRSLTIEL 660
>sp|P42779|BPRV_DICNO Extracellular basic protease OS=Dichelobacter
nodosus OX=870 GN=bprV PE=1 SV=1
Length=603
Score = 97.1 bits (240), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 130/486 (27%), Positives = 199/486 (41%), Gaps = 112/486 (23%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQE--PTDPKFPQQWYLSGVTQRDLNVKA--AWAQGY 142
+ P V+++E R Y + P DP + QQW+ G + VKA W +G+
Sbjct 114 IASNPDVEFVE-------VDRLAYPKAAPNDPSYRQQWHYFG----NYGVKANKVWDRGF 162
Query 143 TGHGIVVSILDDGIEKNHPDLAGNYDPGASF----------DVNDQDPD----------- 181
TG G+VVS++D GI +H DL GN PG F D D +P
Sbjct 163 TGQGVVVSVVDTGI-LDHVDLNGNMLPGYDFISSAPNARDGDQRDNNPADEGDWFDNWDC 221
Query 182 ---PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML------DGEVT 232
P PR + HG+ AG +AAV NNGV GVAY A++ VR+L D ++T
Sbjct 222 GGYPDPRREKKFSTWHGSHVAGTIAAVTNNGVGVAGVAYGAKVIPVRVLGKCGGYDSDIT 281
Query 233 DAVEARSLGL------NPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLG 286
D + + G N N + + S G G R+ ++ LG
Sbjct 282 DGMYWSAGGHIDGVPDNQNPAQVVNMSLG--GGGGCSQNSQRMIDKTT---------NLG 330
Query 287 SIFVWASGNGGREH-----DSCNCDGYTNSIYTLSISSATQFGN-VPWYSEACSSTLATT 340
++ V A+GN ++ SCN LS+ + T G P+ + LA
Sbjct 331 ALIVIAAGNENQDASRTWPSSCNN--------VLSVGATTPKGKRAPFSNYGARVHLAA- 381
Query 341 YSSGNQNEKQIVTTDLRQ-----KCTESHTGTSASAPLAAGIIALTLEA----NKNLTWR 391
+ T D+ Q GTS +AP +G+ AL + A K LT
Sbjct 382 -----PGTNILSTIDVGQAGPVRSSYGMKAGTSMAAPHVSGVAALVISAANSIGKTLTPS 436
Query 392 DMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALA---QNWTTVAPQR 448
++ ++V+T+ + N ++ G G++DA A V QN P
Sbjct 437 ELSDILVRTT--SRFNG----------RLDRGLGSGIVDANAAVNAVLGDQNRAQPRPPV 484
Query 449 KCIIDILTEPKDIGKRLEVR--KTVTACLGEPNHITRLEHAQARLTLS--YNRRGDLAIH 504
I+ + +R+ +R ++VT+ + N R+ A LTL Y R LA+
Sbjct 485 NQPINSGNKVYRSDRRVAIRDLRSVTSGI-RVNDQARVGSANITLTLDIRYGDRSQLAVE 543
Query 505 LVSPMG 510
L++P G
Sbjct 544 LIAPSG 549
>sp|Q9L5A4|ASP_AERSO Aeromonas extracellular serine protease OS=Aeromonas
sobria OX=646 GN=asp PE=1 SV=2
Length=624
Score = 94.7 bits (234), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 132/549 (24%), Positives = 210/549 (38%), Gaps = 128/549 (23%)
Query 115 DPKFPQQWYL-----------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDL 163
+P QQWYL G+ DLN+ A G G G+ V+++DDG+ HPDL
Sbjct 53 NPLQDQQWYLLNSGQDGFSARGGIAGNDLNLWWAHRTGVLGQGVNVAVVDDGLAIAHPDL 112
Query 164 AGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGG 223
A N PG+ V D HGT +G +AAV +N + G+A A++ G
Sbjct 113 ADNVRPGSKNVVTGS----DDPTPTDPDTAHGTSVSGIIAAV-DNAIGTKGIAPRAQLQG 167
Query 224 VRMLDGEVTDAVEARSLGLNPNHI----HIYSASWG-----PED----DGKTVDGPARLA 270
+LD + L ++ +++ S+G P D +D RL
Sbjct 168 FNLLDDNSQQLQKDWLYALGDSNASRDNRVFNQSYGMSVVDPRSANSLDQSQLD---RLF 224
Query 271 EE--------AFFRGVSQGRGGL--GSIFVWASGNGGR-EHDSCNCDGYTNSIYTLSISS 319
E+ A+ + G + G + +GNG + ++ N D ++ + L +S+
Sbjct 225 EQQTLKAQGAAYIKAAGNGFNKIAAGGYVLNRTGNGPKLPFENSNLDPSNSNFWNLVVSA 284
Query 320 ATQFGNVPWYSEACSST-LATTYSSGNQNEKQIVTTDL------RQKCTESHT------- 365
G YS S+ L+ T + +VTTDL + + T
Sbjct 285 LNADGVRSSYSSVGSNIFLSATGGEYGTDTPAMVTTDLPGCDMGYNRTDDPSTNRLHGNS 344
Query 366 -------------GTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTS-------KPAH 405
GTS++ P +G +AL + A +L+ RD++ L+ +++ +P
Sbjct 345 QLDASCDYNGVMNGTSSATPSTSGAMALLMSAYPDLSVRDLRDLLARSATRVDAKHQPVM 404
Query 406 LNAND-------------WATNGVGRKVSHSYGYGLLDAGAMVALAQN-----------W 441
++ W N G S +YG+GL+D + LA N W
Sbjct 405 VSYTSSTGKVRDVKGLEGWERNAAGMWFSPTYGFGLIDVNKALELAANHQPLPPLVQLPW 464
Query 442 --TTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRG 499
V I D+ P R+ TV E Q ++L + R
Sbjct 465 QKINVTGSAAAIADVGNSPTSSTTRIATPLTV-------------EAVQVMVSLDHQRLP 511
Query 500 DLAIHLVSPMGTRSTLLA------ARPHDYSADGF------NDWAFMTTHSWDEDPSGEW 547
DL I LVSP GTRS LL+ + D GF D ++ + E G W
Sbjct 512 DLLIELVSPAGTRSILLSPFNSLVGQSLDQQQLGFVRTKGLRDMRMLSNKFYGESAQGTW 571
Query 548 VLEIENTSE 556
LE+ + +
Sbjct 572 RLEVTDVAN 580
>sp|P42780|BPRX_DICNO Extracellular subtilisin-like protease OS=Dichelobacter
nodosus OX=870 PE=3 SV=1
Length=595
Score = 85.5 bits (210), Expect = 6e-16, Method: Compositional matrix adjust.
Identities = 127/528 (24%), Positives = 212/528 (40%), Gaps = 119/528 (23%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ P V+++E R + P DP + QW+ ++ + W +G TG G
Sbjct 112 IASNPDVEYVEVDRWLRP-----FAAPNDPFYNDQWHY--YSEYGVKADKVWDRGITGKG 164
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVND-----QDPD-------------------- 181
+ V+++D GI NHPDL N PG+ +D QD D
Sbjct 165 VTVAVVDTGI-VNHPDLNANVIPGSGYDFIQEAEIAQDGDGRDSNPADAGDWHSNWACGK 223
Query 182 -PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
P PRY + N + HG+ AG +AAV NN + GVAY+A+I VR+L R
Sbjct 224 YPDPRYEKRNSSWHGSHVAGTIAAVTNNRIGVSGVAYDAKIVPVRVL---------GRCG 274
Query 241 GLNPN-HIHIYSASWGPEDDGKTVDGPARL-------------AEEAFFRGVSQGRGGLG 286
G N + + +Y A+ G D PA++ E+ +Q LG
Sbjct 275 GYNSDINEGMYWAAGGHIDGVPDNKHPAQVINMSLGGPGVCGSTEQTLINRATQ----LG 330
Query 287 SIFVWASGNGGREHDSCNCDGYT--NSIYTLSISSATQFGNVPWYSEACSSTLATTYSSG 344
+ + A+GN D+ + G T + L++ + T G ++S S + +G
Sbjct 331 ATIIVAAGN-----DNIDAYGVTPASCDNILTVGATTSNGTRAYFSNHGSVVDISAPGAG 385
Query 345 NQNEKQIVTTDLRQKCTESHT---GTSASAPLAAGIIALTLEA----NKNLTWRDMQHLV 397
V + R S++ GTS + P AG+ AL + A NK +T ++ ++
Sbjct 386 ---ITSTVDSGARYPSGPSYSLMDGTSMATPHVAGVAALVISAANSVNKEMTPAQVRDVL 442
Query 398 VQTSKPAHLNANDWATNGV-GRKVSHSYGYGLLDAGAMVALAQNWTTV----------AP 446
V+T + NG R++ G G++DA A V + V A
Sbjct 443 VRTVS---------SFNGTPDRRI----GAGIVDADAAVNAVLDGNVVERPIDELKPQAE 489
Query 447 QRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLV 506
R I ++ + + + ++V G P + + A + + + L + LV
Sbjct 490 YRNPQIKLIRDYQMMFSEIKVN-------GRPGN---TKFAVVKADIRHTDPSQLKLRLV 539
Query 507 SPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENT 554
SP G + + S++ + T DE +G W L+I +T
Sbjct 540 SPKGYEYAVHYDNIKNKSSE-------LITFPRDEQMNGYWRLKIVDT 580
>sp|Q00139|VG47_ICHVA Subtilisin-like protease OS=Ictalurid herpesvirus
1 (strain Auburn) OX=766178 GN=ORF47 PE=3 SV=2
Length=370
Score = 74.3 bits (181), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 80/309 (26%), Positives = 129/309 (42%), Gaps = 48/309 (16%)
Query 249 IYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY 308
+ S SWG DDG + R +GR GLG++ + +GNGG D C DG+
Sbjct 84 VVSESWGCVDDGAAFCDTTGNFRDHRGRVAREGRDGLGTVLIRPAGNGG-PIDDCGADGF 142
Query 309 TNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTS 368
T +I T+ + SE C++ L T NE T KC + +S
Sbjct 143 TQAIGTVVTTVTDYT-----RSERCAAVLVTVPP---PNE----TVWYDGKCGFIPSSSS 190
Query 369 ASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN---ANDWATNGVGRKVSH-SY 424
A+ P+ ++ + A+ LT R +Q ++V+ +KP + W N V + +H ++
Sbjct 191 AAPPILGNMLLALIRAHPTLTLRMIQRILVRAAKPVTVTGWRGRGWWLNRVTDRWTHRNF 250
Query 425 GYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEV---RKTVTACLGEPNHI 481
G+G V+P R +I R E+ R V + +
Sbjct 251 GFG---------------EVSPSR----------LEIEARRELSTSRAPVAWSTLDTCDL 285
Query 482 TRLEHAQARLTLS-YNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
+ +E + RL ++ RG + + + SP GT +L RP D+S D F T W
Sbjct 286 SEVEWVRVRLGIAPAVFRGGVTVEISSPSGTIIEILGKRPLDFSRDEFE--GEFVTPFWG 343
Query 541 EDPSGEWVL 549
E G+W +
Sbjct 344 EPGRGKWTV 352
>sp|P23314|EXPR_XANCP Extracellular protease OS=Xanthomonas campestris
pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB
528 / LMG 568 / P 25) OX=190485 GN=XCC0851 PE=3 SV=1
Length=580
Score = 73.6 bits (179), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 95/359 (26%), Positives = 142/359 (40%), Gaps = 77/359 (21%)
Query 72 VTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQE--------PTDPKFPQQWY 123
V + +L P R R + + L +Q+A + V + P D + +QW
Sbjct 90 VRRLALGPELVRADRALDRAEAETLMRQLAADPNVQSVEVDQILHATLTPNDTRLSEQWA 149
Query 124 LSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF--------DV 175
G T LN++ AW + TG G VV+++D GI +H DL N G F D
Sbjct 150 F-GTTNAGLNIRPAWDKA-TGSGTVVAVIDTGI-TSHADLNANILAGYDFISDATTARDG 206
Query 176 NDQDPDPQPRYTQMNDNR------------HGTRCAGEVAAVANNGVCGVGVAYNARIGG 223
N +D + N HGT AG VAAV NN G AY A++
Sbjct 207 NGRDSNAADEGDWYAANECGAGIPAASSSWHGTHVAGTVAAVTNNTTGVAGTAYGAKVVP 266
Query 224 VRML---DGEVTDAVEA---------RSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAE 271
VR+L G ++D +A + N N + + S G T +
Sbjct 267 VRVLGKCGGSLSDIADAIVWASGGTVSGIPANANPAEVINMSLGGGGSCSTT------MQ 320
Query 272 EAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY--TNSIYTLSISSATQFGNVPWY 329
A VS+ G+ V A+GN D+ N G N +++++ T G Y
Sbjct 321 NAINGAVSR-----GTTVVVAAGN-----DASNVSGSLPANCANVIAVAATTSAGAKASY 370
Query 330 S--------EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIAL 380
S A S++ +T +SG TT S+ GTS ++P AG++AL
Sbjct 371 SNFGTGIDVSAPGSSILSTLNSG--------TTTPGSASYASYNGTSMASPHVAGVVAL 421
>sp|P16396|SUBE_BACSU Minor extracellular protease Epr OS=Bacillus
subtilis (strain 168) OX=224308 GN=epr PE=1 SV=1
Length=645
Score = 68.6 bits (166), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 107/387 (28%), Positives = 160/387 (41%), Gaps = 76/387 (20%)
Query 87 LQREPQVQWLEQQV---AKRRTKRDVYQEPTDPKFP-QQWYLSGVTQRDLNVKAAWAQGY 142
L+++P + ++E V A T V + TD +QW L + VK AW G
Sbjct 77 LKQDPDILYVENNVSFTAADSTDFKVLSDGTDTSDNFEQWNLEPI-----QVKQAWKAGL 131
Query 143 TGHGIVVSILDDGIEKNHPDL--AGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAG 200
TG I ++++D GI H DL AG Y S+ + +D DN HGT AG
Sbjct 132 TGKNIKIAVIDSGISP-HDDLSIAGGY-SAVSYTSSYKD-----------DNGHGTHVAG 178
Query 201 EVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNHIHIYSASWGPE 257
+ A +NG G+A A+I V+ LD + +++ G++ N + I + S G
Sbjct 179 IIGA-KHNGYGIDGIAPEAQIYAVKALDQNGSGDLQSLLQGIDWSIANRMDIVNMSLGTT 237
Query 258 DDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSI 317
D K + +A+ +GV + V ASGN G Y++ +
Sbjct 238 SDSKILHDAVN---KAYEQGV---------LLVAASGNDGNGKPVNYPAAYSSVVAV--- 282
Query 318 SSATQFGNVPWYSEACSSTLATTYSSGNQNE-----KQIVTTDLRQKCTESHTGTSASAP 372
SAT N LA+ ++G++ E I +T L Q + +GTS + P
Sbjct 283 -SATNEKN----------QLASFSTTGDEVEFSAPGTNITSTYLNQYYA-TGSGTSQATP 330
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAG 432
AA + AL L RD VQ + N D T G ++ +GYGL+
Sbjct 331 HAAAMFAL-------LKQRDPAETNVQLREEMRKNIVDLGTAGRDQQ----FGYGLIQYK 379
Query 433 AMV-----ALAQNWTTVAPQRKCIIDI 454
A A A+ A Q K IDI
Sbjct 380 AQATDSAYAAAEQAVKKAEQTKAQIDI 406
>sp|P04072|THET_THEVU Thermitase OS=Thermoactinomyces vulgaris
OX=2026 PE=1 SV=1
Length=279
Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 46/116 (40%), Positives = 56/116 (48%), Gaps = 13/116 (11%)
Query 113 PTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS 172
P DP F + Y + + AW G G ++I+D G++ NHPDLAG G
Sbjct 3 PNDPYFSSRQY----GPQKIQAPQAWDIA-EGSGAKIAIVDTGVQSNHPDLAGKVVGG-- 55
Query 173 FDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD 228
+D D D PQ N N HGT CAG AAV NN G A A I VR+LD
Sbjct 56 WDFVDNDSTPQ------NGNGHGTHCAGIAAAVTNNSTGIAGTAPKASILAVRVLD 105
>sp|P29143|HLY_NATA1 Halolysin OS=Natrialba asiatica (strain ATCC
700177 / DSM 12278 / JCM 9576 / FERM P-10747 / NBRC 102637
/ 172P1) OX=29540 GN=hly PE=1 SV=1
Length=530
Score = 66.2 bits (160), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 86/351 (25%), Positives = 143/351 (41%), Gaps = 67/351 (19%)
Query 99 QVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEK 158
+ A+ + P DP++ QQ+ + +N +AAW Y G+ +S++D GI+
Sbjct 108 EYAEDNATYEAIATPNDPQYGQQY-----APQQVNCEAAWDVTYGDPGVTISVVDQGIQY 162
Query 159 NHPDLAGNYDPGASF---DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGV 215
+H DL GN D S D D D DP P N HGT G A NN G+
Sbjct 163 DHEDLEGNMDGSVSNYGDDFVDNDGDPYPVSASEN---HGTHVGGIAAGGTNNATGHAGI 219
Query 216 AYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAE 271
+ N + R L G +TD +A + + + S G +T+ + E
Sbjct 220 S-NCSLLSARALGDGGGGSLTDIADAIQWSADQG-ADVINMSLGGGGFSQTL---SNACE 274
Query 272 EAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI-------YTLSISSATQFG 324
A+ + GS+ V A+GN GY NS+ +++SS +
Sbjct 275 YAYNQ---------GSLLVAAAGN-----------GYGNSVSYPAAYDTVMAVSSLDEGE 314
Query 325 NVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA 384
+ +S + GN V + + ++ +GTS ++P+ AG+ TL A
Sbjct 315 TLSAFSN-LGPEIELAAPGGN------VLSSIPWDNYDTFSGTSMASPVVAGVAGFTLSA 367
Query 385 NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMV 435
+ NL+ +++ + T+ L+ S G+G +DAG V
Sbjct 368 HPNLSNAELRSHLQNTAVDVGLS-------------SEEQGHGRVDAGQAV 405
>sp|P29141|SUBV_BACSU Minor extracellular protease Vpr OS=Bacillus
subtilis (strain 168) OX=224308 GN=vpr PE=1 SV=1
Length=806
Score = 65.5 bits (158), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 43/96 (45%), Positives = 52/96 (54%), Gaps = 11/96 (11%)
Query 137 AWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNR--- 193
AW GYTG GI V+I+D G+E NHPDL N+ +D D D D P+ T D R
Sbjct 173 AWDLGYTGKGIKVAIIDTGVEYNHPDLKKNFGQYKGYDFVDNDYD--PKETPTGDPRGEA 230
Query 194 --HGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
HGT AG VAA NG GVA +A + R+L
Sbjct 231 TDHGTHVAGTVAA---NGTIK-GVAPDATLLAYRVL 262
>sp|P29599|SUBB_LEDLE Subtilisin BL OS=Lederbergia lenta OX=1467
PE=1 SV=1
Length=269
Score = 61.6 bits (148), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 80/268 (30%), Positives = 120/268 (45%), Gaps = 52/268 (19%)
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHG 195
AA +G TG G+ V++LD GI HPDL N GASF +P Q + N HG
Sbjct 15 AAHNRGLTGSGVKVAVLDTGIST-HPDL--NIRGGASFV--PGEPSTQ------DGNGHG 63
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGL---NPNHIHIYSA 252
T AG +AA+ NN + +GVA +A + V++L + A+ + + GL N +H+ +
Sbjct 64 THVAGTIAAL-NNSIGVLGVAPSAELYAVKVLGADGRGAISSIAQGLEWAGNNGMHVANL 122
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
S G T++ + A RGV + V ASGN G S Y N+
Sbjct 123 SLGSPSPSATLE---QAVNSATSRGV---------LVVAASGNSGASSISYPAR-YANA- 168
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCT------ESHTG 366
+++ + Q N +S+ Y +G IV + + T S G
Sbjct 169 --MAVGATDQNNNRASFSQ---------YGAG----LDIVAPGVNVQSTYPGSTYASLNG 213
Query 367 TSASAPLAAGIIALTLEANKNLTWRDMQ 394
TS + P AG AL + KN +W ++Q
Sbjct 214 TSMATPHVAGAAALVKQ--KNPSWSNVQ 239
>sp|P04189|SUBT_BACSU Subtilisin E OS=Bacillus subtilis (strain
168) OX=224308 GN=aprE PE=1 SV=3
Length=381
Score = 62.0 bits (149), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 44/144 (31%), Positives = 75/144 (52%), Gaps = 28/144 (19%)
Query 86 RLQREPQVQWLEQ-QVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+++P V ++E+ +A + Y G++Q + A +QGYTG
Sbjct 87 ELKKDPSVAYVEEDHIAHEYAQSVPY---------------GISQ--IKAPALHSQGYTG 129
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
+ V+++D GI+ +HPDL N GASF ++ +P + + HGT AG +AA
Sbjct 130 SNVKVAVIDSGIDSSHPDL--NVRGGASFVPSETNP-------YQDGSSHGTHVAGTIAA 180
Query 205 VANNGVCGVGVAYNARIGGVRMLD 228
+ NN + +GVA +A + V++LD
Sbjct 181 L-NNSIGVLGVAPSASLYAVKVLD 203
>sp|P35835|SUBN_BACNA Subtilisin NAT OS=Bacillus subtilis subsp.
natto OX=86029 GN=aprN PE=1 SV=1
Length=381
Score = 62.0 bits (149), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 44/144 (31%), Positives = 75/144 (52%), Gaps = 28/144 (19%)
Query 86 RLQREPQVQWLEQ-QVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+++P V ++E+ +A + Y G++Q + A +QGYTG
Sbjct 87 ELKKDPSVAYVEEDHIAHEYAQSVPY---------------GISQ--IKAPALHSQGYTG 129
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
+ V+++D GI+ +HPDL N GASF ++ +P + + HGT AG +AA
Sbjct 130 SNVKVAVIDSGIDSSHPDL--NVRGGASFVPSETNP-------YQDGSSHGTHVAGTIAA 180
Query 205 VANNGVCGVGVAYNARIGGVRMLD 228
+ NN + +GVA +A + V++LD
Sbjct 181 L-NNSIGVLGVAPSASLYAVKVLD 203
>sp|P29142|SUBT_GEOSE Subtilisin J OS=Geobacillus stearothermophilus
OX=1422 GN=aprJ PE=3 SV=1
Length=381
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 43/144 (30%), Positives = 75/144 (52%), Gaps = 28/144 (19%)
Query 86 RLQREPQVQWLEQ-QVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+++P V ++E+ +A + Y G++Q + A +QGYTG
Sbjct 87 ELKKDPSVAYVEEDHIAHEYAQSVPY---------------GISQ--IKAPALHSQGYTG 129
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
+ V+++D GI+ +HPDL N GASF ++ +P + + HGT AG +AA
Sbjct 130 SNVKVAVIDSGIDSSHPDL--NVRGGASFVPSETNP-------YQDGSSHGTHVAGTIAA 180
Query 205 VANNGVCGVGVAYNARIGGVRMLD 228
+ NN + +GV+ +A + V++LD
Sbjct 181 L-NNSIGVLGVSPSASLYAVKVLD 203
>sp|P00783|SUBT_BACSA Subtilisin amylosacchariticus OS=Bacillus
subtilis subsp. amylosacchariticus OX=1483 GN=apr PE=1 SV=2
Length=381
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 43/144 (30%), Positives = 75/144 (52%), Gaps = 28/144 (19%)
Query 86 RLQREPQVQWLEQ-QVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+++P V ++E+ +A + Y G++Q + A +QGYTG
Sbjct 87 ELKKDPSVAYVEEDHIAHEYAQSVPY---------------GISQ--IKAPALHSQGYTG 129
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
+ V+++D GI+ +HPDL N GASF ++ +P + + HGT AG +AA
Sbjct 130 SNVKVAVIDSGIDSSHPDL--NVRGGASFVPSETNP-------YQDGSSHGTHVAGTIAA 180
Query 205 VANNGVCGVGVAYNARIGGVRMLD 228
+ NN + +GV+ +A + V++LD
Sbjct 181 L-NNSIGVLGVSPSASLYAVKVLD 203
>sp|P27693|ELYA_ALKAL Alkaline protease OS=Alkalihalobacillus
alcalophilus OX=1445 PE=1 SV=1
Length=380
Score = 60.1 bits (144), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 89/317 (28%), Positives = 135/317 (43%), Gaps = 68/317 (21%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
L+ +P + ++E+ + V W +S V AA +G TG G
Sbjct 93 LELDPAISYIEEDAEVTTMAQSV-----------PWGISRV-----QAPAAHNRGLTGSG 136
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ V++LD GI HPDL N GASF P TQ + N HGT AG +AA+
Sbjct 137 VKVAVLDTGI-STHPDL--NIRGGASF-------VPGEPSTQ-DGNGHGTHVAGTIAAL- 184
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGL---NPNHIHIYSASWGPEDDGKTV 263
NN + +GVA NA + V++L + +V + + GL N +H+ + S G T+
Sbjct 185 NNSIGVLGVAPNAELYAVKVLGASGSGSVSSIAQGLEWAGNNGMHVANLSLGSPSPSATL 244
Query 264 DGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQF 323
+ + A RGV + V ASGN G S Y N+ +++ + Q
Sbjct 245 E---QAVNSATSRGV---------LVVAASGNSGAGSISYPAR-YANA---MAVGATDQN 288
Query 324 GNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCT------ESHTGTSASAPLAAGI 377
N +S+ Y +G IV + + T S GTS + P AG
Sbjct 289 NNRASFSQ---------YGAG----LDIVAPGVNVQSTYPGSTYASLNGTSMATPHVAGA 335
Query 378 IALTLEANKNLTWRDMQ 394
AL + KN +W ++Q
Sbjct 336 AALVKQ--KNPSWSNVQ 350
>sp|Q99405|PRTM_SHOC1 M-protease OS=Shouchella clausii (strain
KSM-K16) OX=66692 GN=aprE PE=1 SV=2
Length=380
Score = 59.3 bits (142), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 96/356 (27%), Positives = 148/356 (42%), Gaps = 80/356 (22%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
L+ +P + ++E+ + V W +S V AA +G TG G
Sbjct 93 LELDPTISYIEEDAEVTTMAQSV-----------PWGISRV-----QAPAAHNRGLTGSG 136
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ V++LD GI HPDL N GASF P TQ + N HGT AG +AA+
Sbjct 137 VKVAVLDTGIST-HPDL--NIRGGASFV-------PGEPSTQ-DGNGHGTHVAGTIAAL- 184
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGL---NPNHIHIYSASWGPEDDGKTV 263
NN + +GVA +A + V++L + +V + + GL N +H+ + S G
Sbjct 185 NNSIGVLGVAPSAELYAVKVLGASGSGSVSSIAQGLEWAGNNGMHVANLSLGSPS----- 239
Query 264 DGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQF 323
P+ E+A S+G + V ASGN G S Y N+ +++ + Q
Sbjct 240 --PSATLEQAVNSATSRGV-----LVVAASGNSGAGSISYPAR-YANA---MAVGATDQN 288
Query 324 GNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCT------ESHTGTSASAPLAAGI 377
N +S+ Y +G IV + + T S GTS + P AG+
Sbjct 289 NNRASFSQ---------YGAG----LDIVAPGVNVQSTYPGSTYASLNGTSMATPHVAGV 335
Query 378 IALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGA 433
AL + KN +W ++Q N G ++ YG GL++A A
Sbjct 336 AALVKQ--KNPSWSNVQI------------RNHLKNTATGLGNTNLYGSGLVNAEA 377
>sp|P07518|SUBT_BACPU Subtilisin OS=Bacillus pumilus OX=1408 GN=apr
PE=1 SV=1
Length=275
Score = 58.2 bits (139), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 37/103 (36%), Positives = 61/103 (59%), Gaps = 12/103 (12%)
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPR 185
G++Q + A +QGYTG + V+++D GI+ +HPDL N GASF ++ +P
Sbjct 7 GISQ--IKAPALHSQGYTGSNVKVAVIDSGIDSSHPDL--NVRGGASFVPSETNP----- 57
Query 186 YTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD 228
+ + HGT AG +AA+ NN + +GVA ++ + V++LD
Sbjct 58 --YQDGSSHGTHVAGTIAAL-NNSIGVLGVAPSSALYAVKVLD 97
>sp|P41362|ELYA_SHOCL Alkaline protease OS=Shouchella clausii
OX=79880 PE=1 SV=1
Length=380
Score = 58.2 bits (139), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 88/317 (28%), Positives = 135/317 (43%), Gaps = 68/317 (21%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
L+ +P + ++E+ + V W +S V AA +G TG G
Sbjct 93 LELDPAISYIEEDAEVTTMAQSV-----------PWGISRV-----QAPAAHNRGLTGSG 136
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ V++LD GI HPDL N GASF P TQ + N HGT AG +AA+
Sbjct 137 VKVAVLDTGI-STHPDL--NIRGGASF-------VPGEPSTQ-DGNGHGTHVAGTIAAL- 184
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGL---NPNHIHIYSASWGPEDDGKTV 263
NN + +GVA +A + V++L + +V + + GL N +H+ + S G T+
Sbjct 185 NNSIGVLGVAPSAELYAVKVLGASGSGSVSSIAQGLEWAGNNGMHVANLSLGSPSPSATL 244
Query 264 DGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQF 323
+ + A RGV + V ASGN G S Y N+ +++ + Q
Sbjct 245 E---QAVNSATSRGV---------LVVAASGNSGAGSISYPAR-YANA---MAVGATDQN 288
Query 324 GNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCT------ESHTGTSASAPLAAGI 377
N +S+ Y +G IV + + T S GTS + P AG
Sbjct 289 NNRASFSQ---------YGAG----LDIVAPGVNVQSTYPGSTYASLNGTSMATPHVAGA 335
Query 378 IALTLEANKNLTWRDMQ 394
AL + KN +W ++Q
Sbjct 336 AALVKQ--KNPSWSNVQ 350
>sp|P29600|SUBS_LEDLE Subtilisin Savinase OS=Lederbergia lenta
OX=1467 PE=1 SV=1
Length=269
Score = 57.0 bits (136), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 80/268 (30%), Positives = 120/268 (45%), Gaps = 52/268 (19%)
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHG 195
AA +G TG G+ V++LD GI HPDL N GASF +P Q + N HG
Sbjct 15 AAHNRGLTGSGVKVAVLDTGIST-HPDL--NIRGGASFV--PGEPSTQ------DGNGHG 63
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGL---NPNHIHIYSA 252
T AG +AA+ NN + +GVA +A + V++L + +V + + GL N +H+ +
Sbjct 64 THVAGTIAAL-NNSIGVLGVAPSAELYAVKVLGASGSGSVSSIAQGLEWAGNNGMHVANL 122
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
S G T++ + A RGV + V ASGN G S Y N+
Sbjct 123 SLGSPSPSATLE---QAVNSATSRGV---------LVVAASGNSGAGSISYPAR-YANA- 168
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCT------ESHTG 366
+++ + Q N +S+ Y +G IV + + T S G
Sbjct 169 --MAVGATDQNNNRASFSQ---------YGAG----LDIVAPGVNVQSTYPGSTYASLNG 213
Query 367 TSASAPLAAGIIALTLEANKNLTWRDMQ 394
TS + P AG AL + KN +W ++Q
Sbjct 214 TSMATPHVAGAAALVKQ--KNPSWSNVQ 239
>sp|Q45670|THES_BACSJ Thermophilic serine proteinase OS=Bacillus
sp. (strain AK1) OX=268807 PE=1 SV=1
Length=401
Score = 57.8 bits (138), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 44/125 (35%), Positives = 56/125 (45%), Gaps = 22/125 (18%)
Query 137 AWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGT 196
AW G ++++D G++ HPDL G G F ND DP M+ N HGT
Sbjct 144 AWDVTKGSSGQEIAVIDTGVDYTHPDLDGKVIKGYDFVDNDYDP--------MDLNNHGT 195
Query 197 RCAGEVAAVANNGVCGVGVAYNARIGGVRMLD----GEVTDAVEARSLGLNPNHIHIYSA 252
AG AA NN G+A N RI VR LD G ++D +A IY+A
Sbjct 196 HVAGIAAAETNNATGIAGMAPNTRILAVRALDRNGSGTLSDIADAI----------IYAA 245
Query 253 SWGPE 257
G E
Sbjct 246 DSGAE 250
>sp|P16588|PROA_VIBAL Alkaline serine exoprotease A OS=Vibrio
alginolyticus OX=663 GN=proA PE=3 SV=1
Length=534
Score = 57.8 bits (138), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 76/329 (23%), Positives = 136/329 (41%), Gaps = 49/329 (15%)
Query 76 SLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVK 135
+LSP + + L+ +P+V ++EQ R D + W L + QR+L +
Sbjct 108 NLSPEQLKD--LRSDPRVDYIEQ---DRILSLDPIVSADANQTNAIWGLDRIDQRNLPLD 162
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHG 195
++ + G G+ ++D G+ H + G G F ND D + N HG
Sbjct 163 NNYSANFDGTGVTAYVIDTGVNNAHVEFGGRSVSGYDFVDNDADAS--------DCNGHG 214
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWG 255
T AG + G GVA N + GVR+L + + G++ + + + G
Sbjct 215 THVAGTI------GGSLYGVAKNVNLVGVRVLSCSGSGSTSGVIAGVD----WVAANASG 264
Query 256 PEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCN------CDGYT 309
P ++ G +A ++ + Q G F+ A+GN D+CN G T
Sbjct 265 PSVANMSLGGGQSVALDSAVQSAVQS----GVSFMLAAGN--SNADACNYSPARVATGVT 318
Query 310 NSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSA 369
T S + + F N W + ++ G+Q + + ++ +GTS
Sbjct 319 VG-STTSTDARSSFSN--W------GSCVDVFAPGSQ-----IKSAWYDGGYKTISGTSM 364
Query 370 SAPLAAGIIALTLEANKNLTWRDMQHLVV 398
+ P AG+ AL L+ N +++ ++ L+V
Sbjct 365 ATPHVAGVAALYLQENSSVSPSQVEALIV 393
>sp|P00782|SUBT_BACAM Subtilisin BPN' OS=Bacillus amyloliquefaciens
OX=1390 GN=apr PE=1 SV=1
Length=382
Score = 57.4 bits (137), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 45/146 (31%), Positives = 74/146 (51%), Gaps = 28/146 (19%)
Query 86 RLQREPQVQWLEQ-QVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+++P V ++E+ VA + Y GV+Q + A +QGYTG
Sbjct 88 ELKKDPSVAYVEEDHVAHAYAQSVPY---------------GVSQ--IKAPALHSQGYTG 130
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
+ V+++D GI+ +HPDL GAS ++ +P ++N HGT AG VAA
Sbjct 131 SNVKVAVIDSGIDSSHPDL--KVAGGASMVPSETNP-------FQDNNSHGTHVAGTVAA 181
Query 205 VANNGVCGVGVAYNARIGGVRMLDGE 230
+ NN + +GVA +A + V++L +
Sbjct 182 L-NNSIGVLGVAPSASLYAVKVLGAD 206
>sp|P20724|ELYA_BACYA Alkaline elastase YaB OS=Bacillus sp. (strain
YaB) OX=72578 GN=ale PE=1 SV=1
Length=378
Score = 57.0 bits (136), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 77/268 (29%), Positives = 121/268 (45%), Gaps = 54/268 (20%)
Query 137 AWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND-NRHG 195
A ++G+TG G+ V++LD GI NH DL GASF P ++D N HG
Sbjct 125 AQSRGFTGTGVRVAVLDTGI-SNHADL--RIRGGASF---------VPGEPNISDGNGHG 172
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNHIHIYSA 252
T+ AG +AA+ NN + +GVA N + GV++L + ++ + GL N +HI +
Sbjct 173 TQVAGTIAAL-NNSIGVLGVAPNVDLYGVKVLGASGSGSISGIAQGLQWAANNGMHIANM 231
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
S G T++ + V+Q G + V ASGN G + Y N+
Sbjct 232 SLGSSAGSATME-----------QAVNQATAS-GVLVVAASGNSGAGNVGFPAR-YANA- 277
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCT------ESHTG 366
+++ + Q N +S+ Y +G IV + + T S G
Sbjct 278 --MAVGATDQNNNRATFSQ---------YGAG----LDIVAPGVGVQSTVPGNGYASFNG 322
Query 367 TSASAPLAAGIIALTLEANKNLTWRDMQ 394
TS + P AG+ AL + KN +W ++Q
Sbjct 323 TSMATPHVAGVAALVKQ--KNPSWSNVQ 348
>sp|I3R794|HLY_HALMT Halolysin OS=Haloferax mediterranei (strain
ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177
/ R-4) OX=523841 GN=hly PE=1 SV=1
Length=519
Score = 57.4 bits (137), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 44/171 (26%), Positives = 76/171 (44%), Gaps = 23/171 (13%)
Query 76 SLSPHRPRH---SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
S +P + R S + + +V++ E K T +Y DPK+ Q+ + +
Sbjct 84 SKAPKQARENFISAITKRDEVKYAE----KNATHEALYT-ANDPKYGSQY-----APQQV 133
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
N +AW + ++++D G++ +HPDL+ + D D D DP P ++D
Sbjct 134 NADSAWDTTLGSSSVKIAVVDQGVKYDHPDLSSQFGSNKGRDFVDNDGDPYPDL--LSDE 191
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-------GEVTDAVE 236
HGT AG A +N G+G N+ + R L ++ DA+E
Sbjct 192 YHGTHVAGIAAGTTDNNE-GIGGISNSTLLSGRALSESGSGSTSDIADAIE 241
>sp|O31788|APRX_BACSU Serine protease AprX OS=Bacillus subtilis
(strain 168) OX=224308 GN=aprX PE=1 SV=1
Length=442
Score = 56.2 bits (134), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 78/293 (27%), Positives = 127/293 (43%), Gaps = 56/293 (19%)
Query 140 QGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
Q TG G+ V+++D GI HPDL G A D+ +Q +P +DN HGT CA
Sbjct 142 QTLTGKGVTVAVVDTGIYP-HPDLEGRIIGFA--DMVNQKTEP------YDDNGHGTHCA 192
Query 200 GEVAAVANNGVCGV-GVAYNARIGGVRMLD----GEVTDAVEARSLGL-----NPNH-IH 248
G+VA+ + G A A + GV++L+ G + D +E + NP+ I
Sbjct 193 GDVASSGASSSGQYRGPAPEANLIGVKVLNKQGSGTLADIIEGVEWCIQYNEDNPDEPID 252
Query 249 IYSASWGPED---DGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNC 305
I S S G + D + D R EEA+ G+ + A+GN G + +
Sbjct 253 IMSMSLGGDALRYDHEQEDPLVRAVEEAWSAGI---------VVCVAAGNSGPDSQTIAS 303
Query 306 DGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEK--------QIVT---- 353
G + + T+ A N + ++ ++ + EK I++
Sbjct 304 PGVSEKVITVG---ALDDNNTASSDDDTVASFSSRGPTVYGKEKPDILAPGVNIISLRSP 360
Query 354 ---TDLRQKCTE------SHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLV 397
D QK + + +GTS + P+ AGI AL L+ N +LT +++ L+
Sbjct 361 NSYIDKLQKSSRVGSQYFTMSGTSMATPICAGIAALILQQNPDLTPDEVKELL 413
>sp|P11018|ISP1_BACSU Major intracellular serine protease OS=Bacillus
subtilis (strain 168) OX=224308 GN=isp PE=1 SV=2
Length=319
Score = 55.1 bits (131), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 74/261 (28%), Positives = 105/261 (40%), Gaps = 55/261 (21%)
Query 138 WAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTR 197
WA+G G I V++LD G + +HPDL G +F D D + N HGT
Sbjct 35 WAKGVKGKNIKVAVLDTGCDTSHPDLKNQIIGGKNF----TDDDGGKEDAISDYNGHGTH 90
Query 198 CAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE------------VTDAVEARSLGLNPN 245
AG +AA +NG GVA A + V++L GE + AVE +
Sbjct 91 VAGTIAANDSNGGI-AGVAPEASLLIVKVLGGENGSGQYEWIINGINYAVEQK------- 142
Query 246 HIHIYSASWGPEDDGKTVDGPARLAE--EAFFRGVSQGRGGLGSIFVWASGNGG----RE 299
+ I S S G GP+ + E EA V G + V A+GN G R
Sbjct 143 -VDIISMSLG---------GPSDVPELKEAVKNAVKN-----GVLVVCAAGNEGDGDERT 187
Query 300 HDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQK 359
+ Y I S+S A + SE ++ + +N + + L K
Sbjct 188 EELSYPAAYNEVIAVGSVSVAREL------SEFSNANKEIDLVAPGEN----ILSTLPNK 237
Query 360 CTESHTGTSASAPLAAGIIAL 380
TGTS +AP +G +AL
Sbjct 238 KYGKLTGTSMAAPHVSGALAL 258
>sp|P29805|PRTT_SERMA Extracellular serine protease OS=Serratia
marcescens OX=615 PE=3 SV=1
Length=1045
Score = 53.9 bits (128), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 42/132 (32%), Positives = 66/132 (50%), Gaps = 28/132 (21%)
Query 110 YQEP---------TDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNH 160
Y+EP + +F +QW L ++ + A+A+ YTG G+ + ++DD I +H
Sbjct 29 YREPGQLGSPDSWKNAEFNRQWGLEAIS-----AEFAYARAYTGKGVTIGVIDDAI-LSH 82
Query 161 PDLAGN---YDPGA-SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVA 216
P+ AG D G+ +F + QD M+ HGT AG +AA +G GVA
Sbjct 83 PEFAGKLTRLDNGSYNFSYDKQD--------NMSFGTHGTHVAG-IAAAKRDGSGMHGVA 133
Query 217 YNARIGGVRMLD 228
Y+A I G ++ D
Sbjct 134 YDADIIGTKLND 145
>sp|Q8IHZ5|SUB2_PLAF7 Subtilisin-like protease 2 OS=Plasmodium
falciparum (isolate 3D7) OX=36329 GN=SUB2 PE=1 SV=1
Length=1341
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 68/229 (30%), Positives = 101/229 (44%), Gaps = 34/229 (15%)
Query 87 LQREPQVQWLEQQVAKRRT--KRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAW-AQGYT 143
L EP + + ++ +KR K + P + + W LS + V AW GY
Sbjct 690 LNIEPLILFAKKLNSKRSNIEKEILNFLPKELRDYSTWNLSIIR-----VFNAWFLAGYG 744
Query 144 GHGIVVSILDDGIEKNHPDLAGN-YDPGASFDVNDQDPDPQPRYTQMNDN-----RHGTR 197
+ V ++D G + NH DL GN Y P + N++ Q Y M N HGT
Sbjct 745 NKNVKVCVVDSGADINHVDLNGNLYIP----EYNEKYEMTQDFYNFMVKNPTDASGHGTH 800
Query 198 CAGEVAAVANN-GVCGVGVAYNARIGGVRMLDGEVT----DAVEARSLGLNPNHIHIYSA 252
G + VAN+ GV VGVA N + +R +DG+ A++A ++ + N I +A
Sbjct 801 VTGIIGGVANDLGV--VGVAPNITLISLRFIDGKKYGGSFHAIKALNVCI-LNKAPIINA 857
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHD 301
SWG D LA E + G GS+ + ASGN ++D
Sbjct 858 SWG----SSHFDVNLHLAVER----LKYTLNGKGSVLIAASGNKSNDND 898
>sp|Q9RYM8|SUB2_DEIRA Probable subtilase-type serine protease
DR_A0283 OS=Deinococcus radiodurans (strain ATCC 13939 / DSM
20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB
9279 / VKM B-1422 / R1) OX=243230 GN=DR_A0283 PE=1 SV=1
Length=728
Score = 53.5 bits (127), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 88/360 (24%), Positives = 142/360 (39%), Gaps = 76/360 (21%)
Query 87 LQREPQV-----QWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQG 141
L RE QV Q +++Q+ RT +D + + L+ KAAW G
Sbjct 117 LMREGQVLYAAAQTVQRQIEPVRTAQDQLGAQAVNQVFDTLPQYALDSNHLHAKAAWDAG 176
Query 142 YTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMN----------- 190
+TG G+ V ++DD + +HPDL N+ G ++ DP YT +
Sbjct 177 FTGKGVKVGVIDDPSDVSHPDLRPNW-AGKAY-----DPATNTTYTTVQGWIDAIDGFDG 230
Query 191 --DNR------HGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAVEARSLG 241
DN+ HGT A +AA A NG VGVA +++ + G + D + ARS+
Sbjct 231 KVDNKVDPGIEHGTAVASTIAA-AKNGQGIVGVAPDSKFYTAAIFQPGFIGDYLVARSVI 289
Query 242 LNPNH-IHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
N + + SWG G + L ++AF + + V ++GN RE
Sbjct 290 WTVNQGAQVINNSWGGT-------GYSPLLKQAFDYALER-----DITVVVSAGNSYREE 337
Query 301 ---------------DSCNCDGYTNSIYTLSISSATQFGNV----PWYSEACSSTLATTY 341
N D S Y +S A +V P + A + Y
Sbjct 338 WRNPAQLPGVIASAALDINNDKAGFSTYGRHVSVAAPGVDVMLASPLFINADGTRKTGGY 397
Query 342 SSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTS 401
+ + Q++ +GTS S P +G+ A+ L A +L ++ L+ +T+
Sbjct 398 TKDGGSGYQLI------------SGTSFSGPYTSGVAAVILGAKPDLDPHQVRRLMEETA 445
>sp|P81719|PIIS_ACHLY Protease 2 small chain (Fragment) OS=Achromobacter
lyticus OX=224 PE=1 SV=1
Length=63
Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 23/54 (43%), Positives = 31/54 (57%), Gaps = 3/54 (6%)
Query 113 PTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
P DP + QQW LSG + AW GY G G +++++D GI +HPDL N
Sbjct 3 PNDPLYSQQWGLSGT--YGIRANTAWDNGYQGQGKIIAVVDTGI-TDHPDLLAN 53
>sp|P31339|ASPA_AERSA Microbial serine proteinase OS=Aeromonas
salmonicida OX=645 GN=aspA PE=1 SV=1
Length=621
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 37/112 (33%), Positives = 55/112 (49%), Gaps = 17/112 (15%)
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS------FDVNDQD 179
G+ DLN+ A G GI V+++DDG+ HPDLA N PG+ D D
Sbjct 71 GMAGNDLNLWWAHRTEVLGQGINVAVVDDGLAIAHPDLADNVRPGSKNVVTGGSDPTPTD 130
Query 180 PDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEV 231
PD PR++ +G +AAV +N + +GVA ++ G +LD +
Sbjct 131 PDRCPRHS----------VSGIIAAV-DNSIGTLGVAPRVQLQGFNLLDDNI 171
Score = 48.5 bits (114), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 58/231 (25%), Positives = 91/231 (39%), Gaps = 45/231 (19%)
Query 366 GTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSK-------PAHLN---AND----- 410
GTS++ P G + L + +L+ RD++ L+ + + P +N AN
Sbjct 352 GTSSATPNTTGAMVL-MAPYPDLSVRDLRDLLARNATRLDANQGPVQINYTAANGERRQV 410
Query 411 -----WATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRL 465
W N G S SYG+GL+D ++ T A L + K G+
Sbjct 411 TGLEGWERNAAGLWYSPSYGFGLVDVNKTQPCSRQPRTAATTGAVA---LAKGKGNGRSP 467
Query 466 E-----VRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARP 520
V + T + + +E Q ++L + R DL I LVSP GTRS LL P
Sbjct 468 SAPSRYVGSSPTRSSTQVDQPLTVEAVQVMVSLDHQRLPDLLIELVSPSGTRSVLL--NP 525
Query 521 HD--------------YSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEA 557
++ G D ++ + E GEW LE+ + + A
Sbjct 526 NNSLVGQSLDRQQLGYVRTKGLRDMRMLSHKFYGEPAHGEWRLEVTDVANA 576
>sp|O97364|SUB2_PLAFA Subtilisin-like protease 2 OS=Plasmodium
falciparum OX=5833 GN=SUB2 PE=1 SV=1
Length=1342
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 88/316 (28%), Positives = 130/316 (41%), Gaps = 53/316 (17%)
Query 87 LQREPQVQWLEQQVAKRRT--KRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAW-AQGYT 143
L EP + + ++ +KR K + P + + W LS + V AW GY
Sbjct 691 LNIEPLILFAKKLNSKRSNIEKEILNFLPKELRDYSTWNLSIIR-----VFNAWFLAGYG 745
Query 144 GHGIVVSILDDGIEKNHPDLAGN-YDPGASFDVNDQDPDPQPRYTQMNDN-----RHGTR 197
+ V ++D G + H DL GN Y P + N++ Q Y M N HGT
Sbjct 746 NKNVKVCVVDSGADIKHVDLNGNLYIP----EYNEKYEMTQDFYNFMVKNPTDASGHGTH 801
Query 198 CAGEVAAVANN-GVCGVGVAYNARIGGVRMLDGEVT----DAVEARSLGLNPNHIHIYSA 252
G + VAN+ GV VGVA N + +R +DG+ A++A ++ + N I +A
Sbjct 802 VTGIIGGVANDLGV--VGVAPNITLISLRFIDGKKYGGSFHAIKALNVCI-LNKAPIINA 858
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS- 311
SWG D LA E + G GS+ + ASGN ++D T +
Sbjct 859 SWG----SSHFDVNLHLAVER----LKYTLNGKGSVLIAASGNKSNDNDISPLYPATFTF 910
Query 312 --IYTL-SISSATQFGNVPWYSEACSSTLA---TTYSSGNQNEKQIVTTDLRQKCTESHT 365
+Y++ SIS + Y LA YS+ N +I T
Sbjct 911 PHVYSVASISRNFEISPFSNYGHKSVHILAPGHHIYSTIPNNSYKIF------------T 958
Query 366 GTSASAPLAAGIIALT 381
GTS +AP G+ AL
Sbjct 959 GTSMAAPHVCGVSALV 974
>sp|P00780|SUBC_BACLI Subtilisin Carlsberg OS=Bacillus licheniformis
OX=1402 GN=subC PE=1 SV=2
Length=379
Score = 50.4 bits (119), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 44/161 (27%), Positives = 72/161 (45%), Gaps = 21/161 (13%)
Query 63 DYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAK--RRTKRDVYQEPTDPKFPQ 120
DY + GV S+ + S + + Q + + AK + ++V +P D + +
Sbjct 39 DYIVGFKSGVKTASVKKDIIKESGGKVDKQFRIINAAKAKLDKEALKEVKNDP-DVAYVE 97
Query 121 QWYLSGVTQRD-------LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
+ +++ + + AQG+ G + V++LD GI+ +HPDL N GASF
Sbjct 98 EDHVAHALAQTVPYGIPLIKADKVQAQGFKGANVKVAVLDTGIQASHPDL--NVVGGASF 155
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVAN-NGVCGV 213
+ + N HGT AG VAA+ N GV GV
Sbjct 156 VAGEA--------YNTDGNGHGTHVAGTVAALDNTTGVLGV 188
>sp|P25036|YSP3_YEAST Subtilisin-like protease 3 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=YSP3
PE=2 SV=2
Length=478
Score = 50.1 bits (118), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 42/162 (26%), Positives = 70/162 (43%), Gaps = 36/162 (22%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGY---- 142
+ ++P ++++EQ+ + + + +E W L V+ R+ K + Q
Sbjct 150 ISQDPIIKFVEQETTVKISNSSLQEEAP-------WGLHRVSHRE---KPKYGQDLEYLY 199
Query 143 ---TGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
G G+ +LD GI+ H D G + GA ND+ D N HGT CA
Sbjct 200 EDAAGKGVTSYVLDTGIDTEHEDFEGRAEWGAVIPANDEASDL---------NGHGTHCA 250
Query 200 GEVAAVANNGVCGVGVAYNARIGGVRML----DGEVTDAVEA 237
G + G GVA N +I V++L +G V+D ++
Sbjct 251 GII------GSKHFGVAKNTKIVAVKVLRSNGEGTVSDVIKG 286
>sp|P29139|ISP_PAEPO Intracellular serine protease OS=Paenibacillus
polymyxa OX=1406 GN=isp PE=1 SV=1
Length=326
Score = 49.3 bits (116), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 33/80 (41%), Positives = 43/80 (54%), Gaps = 8/80 (10%)
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ-DPDPQPRYTQMNDNRH 194
A W Q G G+ V++LD G + +HPDL G +F +D+ DP+ Y N H
Sbjct 33 AVWNQ-TRGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDY-----NGH 86
Query 195 GTRCAGEVAAVAN-NGVCGV 213
GT AG +AA N NGV GV
Sbjct 87 GTHVAGTIAATENENGVVGV 106
>sp|P09489|PRTS_SERMA Extracellular serine protease OS=Serratia
marcescens OX=615 PE=1 SV=1
Length=1045
Score = 50.1 bits (118), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 37/116 (32%), Positives = 61/116 (53%), Gaps = 19/116 (16%)
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN---YDPGA-S 172
+F +QW L ++ + A+A+GYTG GI + ++D+ I +H + +G D G+ +
Sbjct 45 EFNRQWGLEAIS-----AEFAYARGYTGKGITIGVIDNAI-LSHSEFSGKLTRLDNGSYN 98
Query 173 FDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD 228
F + QD M+ HGT AG +AA +G GVA++A I G ++ D
Sbjct 99 FSYDKQD--------NMSFGDHGTHVAG-IAAAKRDGAGMHGVAFDADIIGTKLND 145
>sp|P41363|ELYA_HALH5 Thermostable alkaline protease OS=Halalkalibacterium
halodurans (strain ATCC BAA-125 / DSM 18197 / FERM
7344 / JCM 9153 / C-125) OX=272558 GN=BH0855 PE=1 SV=2
Length=361
Score = 49.3 bits (116), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 55/173 (32%), Positives = 87/173 (50%), Gaps = 31/173 (18%)
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDL--AGNYDPGASFDVNDQDPDPQPRYTQM 189
+N + A +G G+G V++LD GI +HPDL AG GASF +P Y
Sbjct 103 INTQQAHNRGIFGNGARVAVLDTGI-ASHPDLRIAG----GASF------ISSEPSY--H 149
Query 190 NDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNH 246
++N HGT AG +AA+ NN + +GVA +A + V++LD + ++ + + G+ N+
Sbjct 150 DNNGHGTHVAGTIAAL-NNSIGVLGVAPSADLYAVKVLDRNGSGSLASVAQGIEWAINNN 208
Query 247 IHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGRE 299
+HI + S G T++ A A G + V A+GN GR+
Sbjct 209 MHIINMSLGSTSGSSTLELAVNRANNA------------GILLVGAAGNTGRQ 249
>sp|P29138|CUDP_METAN Cuticle-degrading protease OS=Metarhizium
anisopliae OX=5530 GN=PR1 PE=1 SV=1
Length=388
Score = 49.3 bits (116), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 56/228 (25%), Positives = 87/228 (38%), Gaps = 42/228 (18%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
+H + +TK L L+ P V ++E+ R + + ++ P W L
Sbjct 74 FHGFAGSLTKEELK-------MLREHPGVDFIEKDAVMRIS--GITEQSGAP-----WGL 119
Query 125 SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQP 184
++ R G G V I+D GIE +HP+ G SF ++ Q+ D
Sbjct 120 GRISHRSKGSTTYRYDDSAGQGTCVYIIDTGIEASHPEFEGRATFLKSF-ISGQNTD--- 175
Query 185 RYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN- 243
+ HGT CAG + G GVA A++ GV++LD + + + G++
Sbjct 176 ------GHGHGTHCAGTI------GSKTYGVAKKAKLYGVKVLDNQGSGSYSGIISGMDY 223
Query 244 ----------PNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQG 281
PN I S S G G A L F V+ G
Sbjct 224 VAQDSKTRGCPNGA-IASMSLGGGYSASVNQGAAALVNSGVFLAVAAG 270
>sp|W7K9M0|SUB1_PLAFO Subtilisin-like protease 1 OS=Plasmodium
falciparum (isolate NF54) OX=5843 GN=SUB1 PE=1 SV=1
Length=688
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 62/290 (21%), Positives = 112/290 (39%), Gaps = 63/290 (22%)
Query 149 VSILDDGIEKNHPDLAGN-------------YDP----------GASFDVNDQDPDPQPR 185
+ ++D GI+ NHPDL N +D GA+F N +P
Sbjct 368 ICVIDSGIDYNHPDLKDNIELNLKELHGRKGFDDDNNGIVDDIYGANFVNNSGNP----- 422
Query 186 YTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD----GEVTDAVEARSLG 241
M+DN HGT +G ++A+ NN + VGV N+++ + LD G + D +
Sbjct 423 ---MDDNYHGTHVSGIISAIGNNNIGVVGVDVNSKLIICKALDEHKLGRLGDMFKCLDYC 479
Query 242 LNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHD 301
++ N H+ + S+ ++ + + G +F ++ N
Sbjct 480 ISRN-AHMINGSFSFDEYSGIFNSSVEYLQRK------------GILFFVSASNCSHPKS 526
Query 302 SC----NCDGYTNSIY----------TLSISSATQFGNVPWYSEACSSTLATTYSSGNQN 347
S CD N+ Y +S+++ + N YS + +S + Y
Sbjct 527 STPDIRKCDLSINAKYPPILSTVYDNVISVANLKKNDNNNHYSLSINSFYSNKYCQLAAP 586
Query 348 EKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLV 397
I +T GTS +AP A I +L N +L+++ + ++
Sbjct 587 GTNIYST-APHNSYRKLNGTSMAAPHVAAIASLIFSINPDLSYKKVIQIL 635
>sp|Q8I0V0|SUB1_PLAF7 Subtilisin-like protease 1 OS=Plasmodium
falciparum (isolate 3D7) OX=36329 GN=SUB1 PE=1 SV=1
Length=688
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 62/290 (21%), Positives = 112/290 (39%), Gaps = 63/290 (22%)
Query 149 VSILDDGIEKNHPDLAGN-------------YDP----------GASFDVNDQDPDPQPR 185
+ ++D GI+ NHPDL N +D GA+F N +P
Sbjct 368 ICVIDSGIDYNHPDLKDNIELNLKELHGRKGFDDDNNGIVDDIYGANFVNNSGNP----- 422
Query 186 YTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD----GEVTDAVEARSLG 241
M+DN HGT +G ++A+ NN + VGV N+++ + LD G + D +
Sbjct 423 ---MDDNYHGTHVSGIISAIGNNNIGVVGVDVNSKLIICKALDEHKLGRLGDMFKCLDYC 479
Query 242 LNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHD 301
++ N H+ + S+ ++ + + G +F ++ N
Sbjct 480 ISRN-AHMINGSFSFDEYSGIFNSSVEYLQRK------------GILFFVSASNCSHPKS 526
Query 302 SC----NCDGYTNSIY----------TLSISSATQFGNVPWYSEACSSTLATTYSSGNQN 347
S CD N+ Y +S+++ + N YS + +S + Y
Sbjct 527 STPDIRKCDLSINAKYPPILSTVYDNVISVANLKKNDNNNHYSLSINSFYSNKYCQLAAP 586
Query 348 EKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLV 397
I +T GTS +AP A I +L N +L+++ + ++
Sbjct 587 GTNIYST-APHNSYRKLNGTSMAAPHVAAIASLIFSINPDLSYKKVIQIL 635
>sp|O61142|SUB1_PLAFA Subtilisin-like protease 1 OS=Plasmodium
falciparum OX=5833 GN=SUB1 PE=1 SV=1
Length=690
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 62/290 (21%), Positives = 112/290 (39%), Gaps = 63/290 (22%)
Query 149 VSILDDGIEKNHPDLAGN-------------YDP----------GASFDVNDQDPDPQPR 185
+ ++D GI+ NHPDL N +D GA+F N +P
Sbjct 370 ICVIDSGIDYNHPDLKDNIELNLKELHGRKGFDDDNNGIVDDIYGANFVNNSGNP----- 424
Query 186 YTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD----GEVTDAVEARSLG 241
M+DN HGT +G ++A+ NN + VGV N+++ + LD G + D +
Sbjct 425 ---MDDNYHGTHVSGIISAIGNNNIGVVGVDVNSKLIICKALDEHKLGRLGDMFKCLDYC 481
Query 242 LNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHD 301
++ N H+ + S+ ++ + + G +F ++ N
Sbjct 482 ISRN-AHMINGSFSFDEYSGIFNSSVEYLQRK------------GILFFVSASNCSHPKS 528
Query 302 SC----NCDGYTNSIY----------TLSISSATQFGNVPWYSEACSSTLATTYSSGNQN 347
S CD N+ Y +S+++ + N YS + +S + Y
Sbjct 529 STPDIRKCDLSINAKYPPILSTVYDNVISVANLKKNDNNNHYSLSINSFYSNKYCQLAAP 588
Query 348 EKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLV 397
I +T GTS +AP A I +L N +L+++ + ++
Sbjct 589 GTNIYST-APHNSYRKLNGTSMAAPHVAAIASLIFSINPDLSYKKVIQIL 637
>sp|P58371|SPM1_PYRO7 Subtilisin-like proteinase Spm1 OS=Pyricularia
oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507
GN=SPM1 PE=3 SV=1
Length=536
Score = 47.4 bits (111), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 49/190 (26%), Positives = 80/190 (42%), Gaps = 29/190 (15%)
Query 50 RKHG-FLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHS--RLQREPQVQWLEQQ-VAKRRT 105
RK G F ++ F H ++ G + H + +++R P V+ +E+ +
Sbjct 79 RKRGLFDSVNDAFTGLKHTYNVGSGFLGYAGHFDEETIEKVRRHPDVEAIERDTIVHTMR 138
Query 106 KRDVYQEPTDPKFPQQ--WYLSGVTQRD------LNVKAAWAQGYTGHGIVVSILDDGIE 157
+V ++ +P + W LS V+ R+ N A+G G G+ ++D G
Sbjct 139 YEEVKKDECNPDLEKGAPWGLSRVSHRESLSFSTYNKYLYSAEG--GEGVDAYVIDTGTN 196
Query 158 KNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAY 217
+H D G G + NDQD D N HGT C+G VA GVA
Sbjct 197 IDHVDFEGRAHWGKTIPANDQDIDG---------NGHGTHCSGTVAGKK------YGVAK 241
Query 218 NARIGGVRML 227
A++ V++L
Sbjct 242 KAQVYAVKVL 251
>sp|L8G6I7|SUB1_PSED2 Subtilisin-like protease 1 OS=Pseudogymnoascus
destructans (strain ATCC MYA-4855 / 20631-21) OX=658429
GN=SP1 PE=1 SV=1
Length=400
Score = 47.0 bits (110), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 40/158 (25%), Positives = 59/158 (37%), Gaps = 22/158 (14%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
+ P V W+E V + + W L ++ + + G G
Sbjct 100 EIAASPLVAWIEMD-------GKVQANALETRSGATWGLGRISHKATGSNSYIYDGSAGS 152
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G V +LD GI H + G GA++ D D +N HGT CAG +A
Sbjct 153 GSTVYVLDTGIYIEHSEFEGRAKWGANYISGSPDTD---------ENGHGTHCAGTIAGA 203
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN 243
GVA A + V++LD + A A G+N
Sbjct 204 T------YGVASKANLVAVKVLDRDGFGATSATIAGIN 235
>sp|Q68GV9|ALP_LECPS Alkaline serine protease ver112 OS=Lecanicillium
psalliotae OX=73499 PE=1 SV=1
Length=382
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 40/143 (28%), Positives = 56/143 (39%), Gaps = 24/143 (17%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
RL+R+P V+ +EQ Q T W L+ ++ R A G
Sbjct 83 RLRRDPDVESIEQDAIFSINAITQQQGAT-------WGLTRISHRARGSTAYAYDTSAGA 135
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G V ++D G+E HPD G S+ +D + HGT CAG +
Sbjct 136 GACVYVIDTGVEDTHPDFEGRAKQIKSYASTARD-----------GHGHGTHCAGTI--- 181
Query 206 ANNGVCGVGVAYNARIGGVRMLD 228
G GVA I GV++LD
Sbjct 182 ---GSKTWGVAKKVSIFGVKVLD 201
>sp|Q93LQ6|FLS_FERPE Fervidolysin OS=Fervidobacterium pennivorans
OX=93466 GN=fls PE=1 SV=1
Length=699
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 92/382 (24%), Positives = 144/382 (38%), Gaps = 70/382 (18%)
Query 81 RPRHSRLQREPQVQWLEQQVAKRR------TKRDVYQEPTDPKFPQQWYLS--GVTQRDL 132
P + R +P V + K R T RD +E ++ + W L GVTQ+
Sbjct 121 EPSYKRELIKPTVVKPNPDMYKIRKPGLNSTARDYGEELSN----ELWGLEAIGVTQQ-- 174
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
W + +G I+V+++D G++ HPDL G G +++ P
Sbjct 175 ----LWEEA-SGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGT---DSSYGG 226
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD--------GEVTDAVEARSLGLNP 244
HGT AG +AA +G VGVA A+I + + D G V D A +
Sbjct 227 SHGTHVAGTIAA-KKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDYVAAGIIWAT 285
Query 245 NH-IHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSC 303
+H + + SWG G + +EAF + G + V ++GN +
Sbjct 286 DHGAKVMNHSWGGW-------GYSYTMKEAFDYAMEH-----GVVMVVSAGNNTSDSHHQ 333
Query 304 NCDGYTNSIYTLSISSATQFGNVPWYSE------------ACSSTLATTYSSGNQNEKQI 351
GY I ++ V +S ST+ S G + +
Sbjct 334 YPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDSIGYEGHNEN 393
Query 352 VTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDW 411
V + + GTS +AP G++A+ L+ N ++ L+ T+ N N W
Sbjct 394 VPA-TNGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTA--FDFNGNGW 450
Query 412 ATNGVGRKVSHSYGYGL--LDA 431
H GYGL LDA
Sbjct 451 ---------DHDTGYGLVKLDA 463
>sp|Q9Y008|SUB2_PLAFP Subtilisin-like protease 2 OS=Plasmodium
falciparum (isolate Palo Alto / Uganda) OX=57270 GN=SUB2 PE=1
SV=1
Length=1337
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 64/229 (28%), Positives = 98/229 (43%), Gaps = 34/229 (15%)
Query 87 LQREPQVQWLEQQVAKRRT--KRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAW-AQGYT 143
L EP + + ++ +KR K + P + + W LS + V AW GY
Sbjct 686 LNIEPLILFAKKLNSKRSNIEKEILNFLPKELRDYSTWNLSIIR-----VFNAWFLAGYG 740
Query 144 GHGIVVSILDDGIEKNHPDLAGN-YDPGASFDVNDQDPDPQPRYTQMNDNR-----HGTR 197
+ V ++D G + N DL GN Y P + N++ Q Y M HG+
Sbjct 741 NKNVKVCVVDSGADINRVDLNGNLYIP----EYNEKYEMTQDFYNFMVKKSYRCLGHGSH 796
Query 198 CAGEVAAVANN-GVCGVGVAYNARIGGVRMLDGEVT----DAVEARSLGLNPNHIHIYSA 252
G + VAN+ GV VGVA N + +R +DG+ A++A ++ + N I +A
Sbjct 797 VTGIIGGVANDLGV--VGVAPNITLISLRFIDGKKYGGSFHAIKALNVCI-LNKAPIINA 853
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHD 301
SWG D L E + G GS+ + ASGN ++D
Sbjct 854 SWG----SSHFDVNLHLTVER----LKYTLNGKGSVLIAASGNKSNDND 894
>sp|Q80T14|FRAS1_MOUSE Extracellular matrix organizing protein
FRAS1 OS=Mus musculus OX=10090 GN=Fras1 PE=1 SV=2
Length=4010
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 26/77 (34%), Positives = 33/77 (43%), Gaps = 16/77 (21%)
Query 592 SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATC 651
S C CE +L CV CP +TH++ E C CH SC C
Sbjct 724 SPHNCTGCESTHALLAGCCVSQCP--------ETHFNLEG--------TCTECHPSCRQC 767
Query 652 QGPALTDCLSCPSHASL 668
GP +DC+SC H +L
Sbjct 768 HGPLESDCVSCHPHLTL 784
Score = 43.5 bits (101), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 22/71 (31%), Positives = 29/71 (41%), Gaps = 15/71 (21%)
Query 592 SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATC 651
SS C+ C E LH C+ CP G+ C CH+SCA+C
Sbjct 570 SSPRCLSCAEKTILHDGKCISECPHGYYAD---------------STGSCKVCHSSCASC 614
Query 652 QGPALTDCLSC 662
GP C++C
Sbjct 615 SGPTAAHCIAC 625
Score = 39.7 bits (91), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 25/76 (33%), Positives = 30/76 (39%), Gaps = 16/76 (21%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C T T+ C C + Q CV C GF H+S CA CH
Sbjct 471 CSTCTNGLECSSCLPPLLMQQGQCVSTCGDGF----YQDHHS------------CAVCHE 514
Query 647 SCATCQGPALTDCLSC 662
SCA C GP C++C
Sbjct 515 SCAGCWGPTEKHCMAC 530
Score = 38.5 bits (88), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 21/67 (31%), Positives = 26/67 (39%), Gaps = 16/67 (24%)
Query 596 CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPA 655
C+ C +L Q C+ C GF P +C CHASC TC GP
Sbjct 622 CIACIHPQTLRQGHCLPSCGEGFYPD----------------HGICEACHASCHTCVGPQ 665
Query 656 LTDCLSC 662
+ C C
Sbjct 666 PSHCTQC 672
>sp|P58502|TKSU_THEKO Tk-subtilisin OS=Thermococcus kodakarensis
(strain ATCC BAA-918 / JCM 12380 / KOD1) OX=69014 GN=TK1675
PE=1 SV=1
Length=422
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 83/318 (26%), Positives = 126/318 (40%), Gaps = 56/318 (18%)
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND-NRHGTRCAGEVAAV 205
I V++LD G++ +HPDLA N ++ V+ + D N HGT G +AA+
Sbjct 133 IQVAVLDTGVDYDHPDLAANI----AWCVSTLRGKVSTKLRDCADQNGHGTHVIGTIAAL 188
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLG-----LNPNHIHIYSA----SWGP 256
NN + VGVA +I VR+LD + + ++G L P+ + + P
Sbjct 189 -NNDIGVVGVAPGVQIYSVRVLDARGSGSYSDIAIGIEQAILGPDGVADKDGDGIIAGDP 247
Query 257 EDDGKTV-----DGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
+DD V GP A++++ + G + V ASGN G S Y
Sbjct 248 DDDAAEVISMSLGGP---ADDSYLYDMIIQAYNAGIVIVAASGNEGAPSPSYPA-AYPEV 303
Query 312 IYTLSISS---ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTS 368
I +I S F N A + +TY E+ GTS
Sbjct 304 IAVGAIDSNDNIASFSNRQPEVSAPGVDILSTYP---------------DDSYETLMGTS 348
Query 369 ASAPLAAGIIALTLEA-----NKNL---TWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
+ P +G++AL A K L T+ D+ V+ H+ A+D G
Sbjct 349 MATPHVSGVVALIQAAYYQKYGKILPVGTFDDISKNTVRGI--LHITADDLGPTG----W 402
Query 421 SHSYGYGLLDAGAMVALA 438
YGYG++ A V A
Sbjct 403 DADYGYGVVRAALAVQAA 420
>sp|C5P4Z8|SUB8_COCP7 Subtilisin-like protease CPC735_031240 OS=Coccidioides
posadasii (strain C735) OX=222929 GN=CPC735_031240
PE=3 SV=1
Length=497
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 53/197 (27%), Positives = 78/197 (40%), Gaps = 47/197 (24%)
Query 51 KHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVY 110
KH + G I G HF + +++R P VQ++E+ ++ +
Sbjct 94 KHTYDIAGSIMGYSGHFDEEVI------------EQVRRHPDVQYIEKD-----SEVHAW 136
Query 111 QEP-TDPKFPQQWYLSGVTQRD------LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDL 163
EP T+ P W L+ V+ RD N A G G G+ V ++D G H D
Sbjct 137 DEPVTENNAP--WGLARVSHRDSLTMGTFNKYLYAANG--GEGVDVYVIDTGTNIEHVDF 192
Query 164 AGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGG 223
G G + D D D N HGT C+G VA GVA A +
Sbjct 193 EGRAHWGKTIPTGDDDVD---------GNGHGTHCSGTVAGKK------YGVAKKANVYA 237
Query 224 VRML----DGEVTDAVE 236
V++L G ++D V+
Sbjct 238 VKVLRSNGSGTMSDVVK 254
>sp|P09232|PRTB_YEAST Cerevisin OS=Saccharomyces cerevisiae (strain
ATCC 204508 / S288c) OX=559292 GN=PRB1 PE=1 SV=1
Length=635
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 43/160 (27%), Positives = 72/160 (45%), Gaps = 34/160 (21%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPT--DPKFPQQWYLSGVTQRD-LNVKAAWAQGY- 142
+++ P V ++E RD E T D + W L+ ++ R+ LN+ + Y
Sbjct 262 IRQNPLVDFVE---------RDSIVEATEFDTQNSAPWGLARISHRERLNLGSFNKYLYD 312
Query 143 --TGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAG 200
G G+ ++D G+ NH D G + +ND+D ++ N HGT CAG
Sbjct 313 DDAGRGVTSYVIDTGVNINHKDFEKRAIWGKTIPLNDED---------LDGNGHGTHCAG 363
Query 201 EVAAVANNGVCGVGVAYNARIGGVRML----DGEVTDAVE 236
+A+ GVA NA + V++L G ++D V+
Sbjct 364 TIASKH------YGVAKNANVVAVKVLRSNGSGTMSDVVK 397
>sp|P33295|PEPC_ASPNG Subtilisin-like serine protease pepC OS=Aspergillus
niger OX=5061 GN=pepC PE=3 SV=1
Length=533
Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 47/193 (24%), Positives = 75/193 (39%), Gaps = 42/193 (22%)
Query 51 KHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVY 110
K+ F G + G HF H +++R P V ++E R ++
Sbjct 94 KNTFDIAGSLIGYSGHF------------HEDVIEQVRRHPDVDYIE-----RDSEVHTM 136
Query 111 QEPTDPKFPQQWYLSGVTQRDL----NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
+ T+ P W L+ ++ RD N G G+ +D GI +H D G
Sbjct 137 EGATEKNAP--WGLARISHRDSLTFGNFNKYLYASEGGEGVDAYTIDTGINVDHVDFEGR 194
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
G + ND+D ++ N HGT C+G +A GVA A + V++
Sbjct 195 ATWGKTIPTNDED---------LDGNGHGTHCSGTMAGKK------YGVAKKANLYAVKV 239
Query 227 L----DGEVTDAV 235
L G ++D V
Sbjct 240 LRSSGSGTMSDVV 252
>sp|P87184|ALP2_ASPFU Alkaline protease 2 OS=Aspergillus fumigatus
(strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)
OX=330879 GN=alp2 PE=1 SV=1
Length=495
Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 42/166 (25%), Positives = 71/166 (43%), Gaps = 33/166 (20%)
Query 80 HRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRD------LN 133
H ++++ P V+++E+ ++ T D E + P W L+ ++ RD N
Sbjct 111 HEDVIEQVRKHPDVEYIEKD-SEVHTMEDPTVEKSAP-----WGLARISHRDSLSFGTFN 164
Query 134 VKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNR 193
++G G G+ +D GI +H D G G + +D+D D N
Sbjct 165 KYLYASEG--GEGVDAYTIDTGINVDHVDFEGRAQWGKTIPTDDEDAD---------GNG 213
Query 194 HGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML----DGEVTDAV 235
HGT C+G +A GVA A + V++L G ++D V
Sbjct 214 HGTHCSGTIAGRK------YGVAKKANLYAVKVLRSSGSGTMSDVV 253
>sp|B0Y473|ALP2_ASPFC Alkaline protease 2 OS=Aspergillus fumigatus
(strain CBS 144.89 / FGSC A1163 / CEA10) OX=451804 GN=alp2
PE=3 SV=1
Length=495
Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 42/166 (25%), Positives = 71/166 (43%), Gaps = 33/166 (20%)
Query 80 HRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRD------LN 133
H ++++ P V+++E+ ++ T D E + P W L+ ++ RD N
Sbjct 111 HEDVIEQVRKHPDVEYIEKD-SEVHTMEDPTVEKSAP-----WGLARISHRDSLSFGTFN 164
Query 134 VKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNR 193
++G G G+ +D GI +H D G G + +D+D D N
Sbjct 165 KYLYASEG--GEGVDAYTIDTGINVDHVDFEGRAQWGKTIPTDDEDAD---------GNG 213
Query 194 HGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML----DGEVTDAV 235
HGT C+G +A GVA A + V++L G ++D V
Sbjct 214 HGTHCSGTIAGRK------YGVAKKANLYAVKVLRSSGSGTMSDVV 253
>sp|P00781|SUBD_BACLI Subtilisin DY OS=Bacillus licheniformis
OX=1402 GN=apr PE=1 SV=1
Length=274
Score = 43.5 bits (101), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 50/174 (29%), Positives = 75/174 (43%), Gaps = 29/174 (17%)
Query 139 AQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRC 198
AQGY G + V I+D GI +H DL GASF + + N HGT
Sbjct 18 AQGYKGANVKVGIIDTGIAASHTDL--KVVGGASFVSGES--------YNTDGNGHGTHV 67
Query 199 AGEVAAVAN-NGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGL---NPNHIHIYSASW 254
AG VAA+ N GV +GVA N + +++L+ + A G+ N + + + S
Sbjct 68 AGTVAALDNTTGV--LGVAPNVSLYAIKVLNSSGSGTYSAIVSGIEWATQNGLDVINMSL 125
Query 255 GPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY 308
G + + ++A+ G+ + V A+GN G S N GY
Sbjct 126 GGPSGSTALK---QAVDKAYASGI---------VVVAAAGNSGSS-GSQNTIGY 166
>sp|L8FSM5|SUB2_PSED2 Subtilisin-like protease 2 OS=Pseudogymnoascus
destructans (strain ATCC MYA-4855 / 20631-21) OX=658429
GN=SP2 PE=1 SV=1
Length=400
Score = 43.9 bits (102), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 37/158 (23%), Positives = 60/158 (38%), Gaps = 22/158 (14%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
+ P V W+E+ V + + W L ++ + + G
Sbjct 100 EIAASPLVAWIERD-------GKVQANALETRSGATWGLGRISHKATGSNSYVYDSSAGS 152
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G V ++D GI H + G GA++ D D +N HGT CAG +A
Sbjct 153 GSTVYVVDSGIYIEHSEFEGRAKWGANYISGSPDTD---------ENGHGTHCAGTIAGA 203
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN 243
GVA A + V++LDG+ + + G+N
Sbjct 204 T------YGVASKANLVAVKVLDGDGSGSNSGVIAGIN 235
>sp|P08594|AQL1_THEAQ Aqualysin-1 OS=Thermus aquaticus OX=271
GN=pstI PE=1 SV=2
Length=513
Score = 43.9 bits (102), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 34/111 (31%), Positives = 46/111 (41%), Gaps = 18/111 (16%)
Query 119 PQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGA-SFDVND 177
P W L + QRDL + ++ TG G+ V ++D GI H + G G + N
Sbjct 132 PAPWGLDRIDQRDLPLSNSYTYTATGRGVNVYVIDTGIRTTHREFGGRARVGYDALGGNG 191
Query 178 QDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD 228
QD N HGT AG + V GVA + VR+LD
Sbjct 192 QDC-----------NGHGTHVAGTIGGVT------YGVAKAVNLYAVRVLD 225
>sp|Q9P8G3|PEN18_PENRB Subtilisin-like serine protease Pen ch
18.0101 OS=Penicillium rubens OX=1108849 PE=1 SV=1
Length=494
Score = 43.5 bits (101), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query 51 KHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVY 110
KH F G + G HF H +++R P V ++E+ ++ RT +
Sbjct 94 KHTFHIAGSLLGYAGHF------------HEDVIEQIRRHPDVDYIEKD-SEVRTMSEGS 140
Query 111 QEPTDPKFPQQWYLSGVTQRDL----NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
E P W L+ ++ R+ N G G+ ++D G H D G
Sbjct 141 VEKNAP-----WGLARISHRESLSFGNFNKYLYAEEGGEGVDAYVIDTGANVKHVDFEGR 195
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
+ G + D D D N HGT C+G +A GVA A + V++
Sbjct 196 ANWGKTIPQGDADEDG---------NGHGTHCSGTIAGKK------FGVAKKANVYAVKV 240
Query 227 L----DGEVTDAVE 236
L G ++D V+
Sbjct 241 LRSNGSGTMSDVVK 254
>sp|D4AX50|SUB8_ARTBC Subtilisin-like protease 8 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB8
PE=3 SV=1
Length=490
Score = 43.5 bits (101), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 64/256 (25%), Positives = 98/256 (38%), Gaps = 70/256 (27%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRD------LNVKAAWA 139
+++R P V+++E R ++ + T+ P W L+ ++ RD N +
Sbjct 116 QVRRHPDVEYIE-----RDSEVHTLKAATENGAP--WGLARISHRDKLNFGTFNKYIYAS 168
Query 140 QGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
QG G G+ ++D G +H D G G + D D D N HGT C+
Sbjct 169 QG--GEGVDAYVIDTGTNIDHVDFEGRASWGKTIPQGDDDVDG---------NGHGTHCS 217
Query 200 GEVAAVANNGVCGVGVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWG 255
G +A GVA A + V++L G ++D V+ W
Sbjct 218 GTIAGKK------YGVAKKANVYAVKVLRTSGSGTMSDVVKG--------------VQWA 257
Query 256 PEDDGKTVDGPARLAEEAFFRG----VSQGRG-------------GLGSIFVWASGNGGR 298
E K+V G A+ F+G +S G G +G F A+GN
Sbjct 258 AESHLKSV-GEAKKGNRKGFKGSVANMSLGGGKSVTLDRVVDQAVAVGMHFAVAAGN--D 314
Query 299 EHDSCNCD--GYTNSI 312
D+CN G NSI
Sbjct 315 NADACNYSPAGSKNSI 330
>sp|P9WEW5|PCH18_PENRB Subtilisin-like serine protease Pen ch
18 OS=Penicillium rubens OX=1108849 PE=1 SV=1
Length=494
Score = 43.5 bits (101), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query 51 KHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVY 110
KH F G + G HF H +++R P V ++E+ ++ RT +
Sbjct 94 KHTFHIAGSLLGYAGHF------------HEDVIEQIRRHPDVDYIEKD-SEVRTMSEGS 140
Query 111 QEPTDPKFPQQWYLSGVTQRDL----NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
E P W L+ ++ R+ N G G+ ++D G H D G
Sbjct 141 VEKNAP-----WGLARISHRESLSFGNFNKYLYAEEGGEGVDAYVIDTGANVKHVDFEGR 195
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
+ G + D D D N HGT C+G +A GVA A + V++
Sbjct 196 ANWGKTIPQGDADEDG---------NGHGTHCSGTIAGKK------FGVAKKANVYAVKV 240
Query 227 L----DGEVTDAVE 236
L G ++D V+
Sbjct 241 LRSNGSGTMSDVVK 254
>sp|P9WEW6|PCH18_PENCH Subtilisin-like serine protease EN45_078720
OS=Penicillium chrysogenum OX=5076 GN=EN45_078720 PE=3
SV=1
Length=494
Score = 43.5 bits (101), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 41/194 (21%)
Query 51 KHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVY 110
KH F G + G HF H +++R P V ++E+ ++ RT +
Sbjct 94 KHTFHIAGSLLGYAGHF------------HEDVIEQIRRHPDVDYIEKD-SEVRTMSEGS 140
Query 111 QEPTDPKFPQQWYLSGVTQRDL----NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
E P W L+ ++ R+ N G G+ ++D G H D G
Sbjct 141 VEKNAP-----WGLARISHRESLSFGNFNKYLYAEEGGEGVDAYVIDTGANVKHVDFEGR 195
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
+ G + D D D N HGT C+G +A GVA A + V++
Sbjct 196 ANWGKTIPQGDADEDG---------NGHGTHCSGTIAGKK------FGVAKKANVYAVKV 240
Query 227 L----DGEVTDAVE 236
L G ++D V+
Sbjct 241 LRSNGSGTMSDVVK 254
>sp|P06873|PRTK_PARAQ Proteinase K OS=Parengyodontium album OX=37998
GN=PROK PE=1 SV=2
Length=384
Score = 43.1 bits (100), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 35/142 (25%), Positives = 56/142 (39%), Gaps = 26/142 (18%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
L+ P V+++EQ D + W L+ ++ + G G
Sbjct 87 LRAHPDVEYIEQ---------DAVVTINAAQTNAPWGLARISSTSPGTSTYYYDESAGQG 137
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
V ++D GIE +HP+ G ++ Y+ + N HGT CAG V
Sbjct 138 SCVYVIDTGIEASHPEFEGRAQMVKTY-----------YYSSRDGNGHGTHCAGTV---- 182
Query 207 NNGVCGVGVAYNARIGGVRMLD 228
G GVA ++ GV++LD
Sbjct 183 --GSRTYGVAKKTQLFGVKVLD 202
>sp|P54423|WPRA_BACSU Cell wall-associated protease OS=Bacillus
subtilis (strain 168) OX=224308 GN=wprA PE=1 SV=2
Length=894
Score = 43.5 bits (101), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 37/138 (27%), Positives = 63/138 (46%), Gaps = 18/138 (13%)
Query 115 DPKFPQQWYLS------GVTQRDLNVKAA--WAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
D ++P QW L GV D+ + A + +++++D G++ DL G
Sbjct 416 DIQYPYQWPLKNNGENGGVKNADVKYEPANTLLSKRKLNDTLIAVVDTGVDSTLADLKGK 475
Query 167 Y--DPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGV 224
D G +F + + M+D HGT AG +AA ++NG G+ A+I V
Sbjct 476 VRTDLGHNFVGRNNNA--------MDDQGHGTHVAGIIAAQSDNGYSMTGLNAKAKIIPV 527
Query 225 RMLDGEVTDAVEARSLGL 242
++LD + E +LG+
Sbjct 528 KVLDSAGSGDTEQIALGI 545
>sp|C5PCB1|SUB4A_COCP7 Subtilisin-like protease CPC735_066880
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_066880
PE=3 SV=1
Length=397
Score = 42.7 bits (99), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 16/87 (18%)
Query 144 GHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVA 203
G G+++ +D GI+ NHPD G A++ +N D D + N HGT AG A
Sbjct 148 GEGVIIYGVDTGIDVNHPDFEGR----ATWGINTIDQD------NTDGNGHGTHTAGTFA 197
Query 204 AVANNGVCGVGVAYNARIGGVRMLDGE 230
GVA A I GV++LD +
Sbjct 198 GAR------FGVAKKATIVGVKVLDAQ 218
>sp|C5FII2|SUB8_ARTOC Subtilisin-like protease 8 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB8
PE=3 SV=1
Length=490
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 49/196 (25%), Positives = 76/196 (39%), Gaps = 46/196 (23%)
Query 51 KHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVY 110
KH F G + G HF + +++R P V+++E R ++
Sbjct 93 KHTFDIAGGLLGYSGHFDEEVI------------EQVRRHPDVEYIE-----RDSEVRAL 135
Query 111 QEPTDPKFPQQWYLSGVTQRD------LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLA 164
+ T+ P W L+ ++ R N AQG G G+ ++D G H D
Sbjct 136 ESVTENGAP--WGLARISHRKRLNFGTFNKYIYAAQG--GEGVDAYVIDTGTNIEHVDFE 191
Query 165 GNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGV 224
G G + ND D D N HGT C+G +A GVA A + V
Sbjct 192 GRASWGKTIPENDDDIDG---------NGHGTHCSGTIAGKK------YGVAKKAHVHAV 236
Query 225 RML----DGEVTDAVE 236
++L G ++D V+
Sbjct 237 KVLRTSGSGTMSDVVK 252
>sp|P29140|ISP_SHOCL Intracellular alkaline protease OS=Shouchella
clausii OX=79880 PE=3 SV=1
Length=321
Score = 42.4 bits (98), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 33/96 (34%), Positives = 45/96 (47%), Gaps = 7/96 (7%)
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNR-H 194
A W G G ++ ++D G + +HPDLA G + D T +DN H
Sbjct 32 AVWKASAKGAGQIIGVIDTGCQVDHPDLAERIIGGVNLTT-----DYGGVETNFSDNNGH 86
Query 195 GTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE 230
GT AG VAA A G VGVA A + ++ L G+
Sbjct 87 GTHVAGTVAA-AETGSGVVGVAPKADLFIIKALSGD 121
>sp|C5P9H3|SUB7D_COCP7 Subtilisin-like protease CPC735_005570
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_005570
PE=3 SV=1
Length=394
Score = 42.4 bits (98), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 66/144 (46%), Gaps = 25/144 (17%)
Query 86 RLQREPQVQWLEQ-QVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
++ +P V+++E ++A R E D W L+ ++ + + G
Sbjct 95 QIANDPAVKYIEHDRIANARG----LVEQQDAG----WNLARISHKKTGARTYVYDKSAG 146
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
GI V ++D G++ ++PDL G GA+F V++ D D N HGT A +A
Sbjct 147 AGISVCLVDTGVDVDNPDLGGRATWGANF-VDNDDSDG---------NGHGTFLASLIAG 196
Query 205 VANNGVCGVGVAYNARIGGVRMLD 228
+ GVA A+I V++LD
Sbjct 197 QKH------GVAKKAKIIAVKVLD 214
>sp|P80146|SEPR_THESR Extracellular serine proteinase OS=Thermus
sp. (strain Rt41A) OX=32063 PE=1 SV=3
Length=410
Score = 42.4 bits (98), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 38/144 (26%), Positives = 61/144 (42%), Gaps = 23/144 (16%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
+RL+++P+V ++E A + + Q P W L + QR L + + TG
Sbjct 112 ARLRQDPRVAYIE---ADQEVRAFAVQSPA------TWGLDRIDQRTLPLDGRYTYTATG 162
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G+ ++D GI +H + G G +D P + + N HGT AG +
Sbjct 163 AGVHAYVVDTGILLSHQEFTGRI--GKGYDAI------TPGGSAQDCNGHGTHVAGTI-- 212
Query 205 VANNGVCGVGVAYNARIGGVRMLD 228
G GVA + VR+LD
Sbjct 213 ----GGTTYGVAKGVTLHPVRVLD 232
>sp|Q07596|NISP_LACLL Nisin leader peptide-processing serine protease
NisP OS=Lactococcus lactis subsp. lactis OX=1360 GN=nisP
PE=1 SV=1
Length=682
Score = 42.4 bits (98), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 73/255 (29%), Positives = 105/255 (41%), Gaps = 36/255 (14%)
Query 71 GVTKRSLSPHRPRHSR----LQREPQVQWLEQQ---VAKRRTKR-DVYQEPTDPKFPQQW 122
GV S SP R ++ L++ + Q +E Q ++ K+ VY D + QW
Sbjct 174 GVIDNSASPLSYRKAKEVVSLRQPLKNQKVEAQPLLISNSSEKKASVYTNSHDF-WDYQW 232
Query 123 YLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLA---GNY----DPGASFDV 175
+ VT N ++A I V I+D GI + HPDL+ GNY P FD
Sbjct 233 DMKYVT----NNGESYALYQPSKKISVGIIDSGIMEEHPDLSNSLGNYFKNLVPKGGFD- 287
Query 176 NDQDPDPQPRYTQMNDNR-HGTRCAGEVAAVANNGVCGV--GVAYNA-RIGGVRMLDGE- 230
+++PD + + D HGT AG++ AN + GV G+ N R+ G + E
Sbjct 288 -NEEPDETGNPSDIVDKMGHGTEVAGQIT--ANGNILGVAPGITVNIYRVFGENLSKSEW 344
Query 231 VTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFV 290
V A+ R + N + SA G DG E ++ GSI V
Sbjct 345 VARAI--RRAADDGNKVINISAGQYLMISGSYDDGTNDYQEYLNYKSAINYATAKGSIVV 402
Query 291 WASGNGGREHDSCNC 305
A GN DS N
Sbjct 403 AALGN-----DSLNI 412
>sp|Q9Y755|PENC2_PENCI Subtilisin-like serine protease Pen c 2
OS=Penicillium citrinum OX=5077 PE=1 SV=1
Length=457
Score = 42.0 bits (97), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 48/196 (24%), Positives = 78/196 (40%), Gaps = 45/196 (23%)
Query 51 KHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVY 110
KH F G + G HF H +++R P V ++E+ ++ +
Sbjct 94 KHSFHVAGSLMGYAGHF------------HEDVIEQVRRHPDVDYIEKD-----SEVHHF 136
Query 111 QEPTDPKFPQQWYLSGVTQRD------LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLA 164
P+ K W L+ ++ RD N K +A+ G G+ ++D G +H D
Sbjct 137 DSPSVEK-NAPWGLARISHRDSLSFGTFN-KYLYAED-GGEGVDAYVIDTGTNTDHVDFE 193
Query 165 GNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGV 224
G G + D+D D N HGT C+G +A GVA A + V
Sbjct 194 GRASWGKTIPQGDEDVDG---------NGHGTHCSGTIAGKK------YGVAKKANVYAV 238
Query 225 RML----DGEVTDAVE 236
++L G ++D V+
Sbjct 239 KVLRSNGSGTMSDVVK 254
>sp|D4DKQ4|SUB8_TRIVH Subtilisin-like protease 8 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB8 PE=3 SV=1
Length=490
Score = 42.0 bits (97), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 41/161 (25%), Positives = 68/161 (42%), Gaps = 34/161 (21%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRD------LNVKAAWA 139
+++R P V+++E R ++ + T+ P W L+ ++ RD N +
Sbjct 116 QVRRHPDVEYIE-----RDSEVHTLKAATENGAP--WGLARISHRDKLNFGTFNKYIYAS 168
Query 140 QGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
QG G G+ ++D G +H D G G + D D D N HGT C+
Sbjct 169 QG--GEGVDAYVIDTGTNIDHVDFEGRASWGKTIPQGDDDVDG---------NGHGTHCS 217
Query 200 GEVAAVANNGVCGVGVAYNARIGGVRML----DGEVTDAVE 236
G +A GVA A + V++L G ++D V+
Sbjct 218 GTIAGKK------YGVAKKANVYAVKVLRTSGSGTMSDVVK 252
>sp|B3V0K8|CL401_COCLU Subtilisin-like serine protease Cur l 4.0101
OS=Cochliobolus lunatus OX=5503 PE=1 SV=1
Length=506
Score = 42.0 bits (97), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 45/161 (28%), Positives = 66/161 (41%), Gaps = 33/161 (20%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEP-TDPKFPQQWYLSGVTQRDLNVKAAW------A 139
++ P V ++E+ R D EP T+ P W L+ ++ RD W A
Sbjct 117 IRNHPDVDYIERDSEVRILGGD---EPETENNSP--WGLARISHRDSLSFGTWNKYLYAA 171
Query 140 QGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
G G G+ V ++D G +H D G G + D D D N HGT C+
Sbjct 172 DG--GEGVDVYVIDTGTNVDHVDFEGRAKWGKTIPNGDADEDG---------NGHGTHCS 220
Query 200 GEVAAVANNGVCGVGVAYNARIGGVRML----DGEVTDAVE 236
G VA GVA A + V++L G ++D V+
Sbjct 221 GTVAGKK------YGVAKKAHVYAVKVLRSNGSGTMSDVVK 255
>sp|E4UTU7|SUB9_ARTGP Subtilisin-like protease 9 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB9
PE=3 SV=1
Length=402
Score = 41.6 bits (96), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 49/199 (25%), Positives = 76/199 (38%), Gaps = 29/199 (15%)
Query 34 WAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQV 93
WA +I + S+ ++ G L+ G F G+ S + + + R P V
Sbjct 56 WASKIH-----SRSLGKRDGVLD--DFGGLKATFQFEGLKGYSGAFDKKTIELITRNPAV 108
Query 94 QWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILD 153
++E R K D D W L ++ R + G GI + +D
Sbjct 109 DYVE---VDRVVKLDAISTQRDAP---SWGLGRISHRRVGSADYVFDDSAGSGITIYGVD 162
Query 154 DGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGV 213
GI+ HP+ G G + V+D+D D N HGT AG G
Sbjct 163 TGIDIRHPEFGGRAAWGTN-TVDDEDTD---------QNGHGTHTAGTF------GGATY 206
Query 214 GVAYNARIGGVRMLDGEVT 232
G+A A I V++L+ + T
Sbjct 207 GIAKKANIVAVKVLNAQGT 225
>sp|C5P6D1|SUB2A_COCP7 Subtilisin-like protease CPC735_023170
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_023170
PE=3 SV=1
Length=406
Score = 41.6 bits (96), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 71/259 (27%), Positives = 97/259 (37%), Gaps = 59/259 (23%)
Query 138 WAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF-DVNDQDPDPQPRYTQMNDNRHGT 196
W G G V I+D GI K H D G PG + DV D + HG+
Sbjct 146 WYDSKAGEGSFVYIMDTGINKAHVDFEGRAIPGVNLHDVAFDDT-----------HGHGS 194
Query 197 RCAGEVAAVANNGVCG----VGVAYNARIGG------------VRMLDGEVTDAVEARSL 240
CAG +A GV V V R GG V+ + GE A A S+
Sbjct 195 HCAG-IAGSKTYGVAKKATIVDVKVFTRGGGAWSLLMGGLDWSVKNITGEDRQAKSAVSI 253
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
++ GP + + ++ + A EA G V ASGN GR+
Sbjct 254 SIS-----------GPTN--QAMNNAVKAAVEA------------GVTVVVASGNDGRDA 288
Query 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
+ SI SI+S +S SS ++ G E I T +
Sbjct 289 GRNSPGSAPESITVGSINSRRGMDTRSSFSNYGSSV--AIHAPG---EGIISTYKGSRDA 343
Query 361 TESHTGTSASAPLAAGIIA 379
T + +GTS +AP AG+IA
Sbjct 344 TANMSGTSMAAPHVAGLIA 362
>sp|C5FH27|SUB9_ARTOC Subtilisin-like protease 9 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB9
PE=3 SV=1
Length=395
Score = 41.2 bits (95), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 43/167 (26%), Positives = 67/167 (40%), Gaps = 32/167 (19%)
Query 86 RLQREPQVQWLEQ----QVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQG 141
R+ R V ++E ++A T+R+ W L ++ +
Sbjct 99 RITRSSDVDYVEADRVVKMAALNTQRN----------APSWGLGRISHKKAGSFDYVYDS 148
Query 142 YTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGE 201
G GI + +D GI+ +HPD G A++ VN D + + N HGT AG
Sbjct 149 DAGSGITIYGVDTGIDIHHPDFGGR----ATWGVNTVDSE------NSDQNGHGTHTAGT 198
Query 202 VAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGL--NPNH 246
A GVA ARI V++L+ E T + G+ + NH
Sbjct 199 FAGAT------YGVAKKARIIAVKVLNAEGTGSTSGVIQGIEWSTNH 239
>sp|Q8SQJ3|SPL1_ENCCU Putative subtilisin-like proteinase 1 OS=Encephalitozoon
cuniculi (strain GB-M1) OX=284813 GN=SPL1 PE=2
SV=1
Length=465
Score = 41.2 bits (95), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 27/86 (31%), Positives = 41/86 (48%), Gaps = 15/86 (17%)
Query 143 TGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEV 202
+G G+ V +LD G+E HP+ G GA+F P+ +++ HGT CAG +
Sbjct 138 SGKGVDVYVLDTGVEIEHPEFGGRARWGANF---------VPKSPDRDEHGHGTHCAGVI 188
Query 203 AAVANNGVCGVGVAYNARIGGVRMLD 228
G GV + I V++LD
Sbjct 189 ------GGKNFGVTKESSIIAVKVLD 208
>sp|B7ZK61|CH901_DAVTA Subtilisin-like serine protease Cla h 9.0101
OS=Davidiella tassiana OX=29918 PE=1 SV=1
Length=518
Score = 41.2 bits (95), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 42/159 (26%), Positives = 67/159 (42%), Gaps = 28/159 (18%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRD-LNVKAAWAQGYT- 143
+++R P V+ +E R + V ++ + W L+ ++ RD L+ YT
Sbjct 118 QIRRHPDVELVE-----RDQEVHVLGSESEVEKNAPWGLARISHRDSLSFGTFNKYLYTE 172
Query 144 --GHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGE 201
G G+ V ++D G +H D G G + D D D N HGT C+G
Sbjct 173 DGGEGVDVYVVDTGTNVDHVDFEGRASWGKTIPQGDADEDG---------NGHGTHCSGT 223
Query 202 VAAVANNGVCGVGVAYNARIGGVRML----DGEVTDAVE 236
VA GVA A + V++L G ++D V+
Sbjct 224 VAGKK------YGVAKKAHVKAVKVLRSNGSGSMSDVVK 256
>sp|Q86XX4|FRAS1_HUMAN Extracellular matrix organizing protein
FRAS1 OS=Homo sapiens OX=9606 GN=FRAS1 PE=1 SV=2
Length=4008
Score = 41.2 bits (95), Expect = 0.053, Method: Compositional matrix adjust.
Identities = 22/71 (31%), Positives = 28/71 (39%), Gaps = 15/71 (21%)
Query 592 SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATC 651
SS C+ C E LH C+ CP G+ C CH SCA+C
Sbjct 571 SSPRCLTCTEKTVLHDGKCMSECPGGYYADA---------------TGRCKVCHNSCASC 615
Query 652 QGPALTDCLSC 662
GP + C +C
Sbjct 616 SGPTPSHCTAC 626
Score = 40.0 bits (92), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 23/77 (30%), Positives = 28/77 (36%), Gaps = 16/77 (21%)
Query 592 SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATC 651
S C C L C+ CP G+ Q C CH +C C
Sbjct 725 SPHNCTDCGPSHVLLDGQCLSQCPDGYFHQ----------------EGSCTECHPTCRQC 768
Query 652 QGPALTDCLSCPSHASL 668
GP +DC+SC H SL
Sbjct 769 HGPLESDCISCYPHISL 785
Score = 39.7 bits (91), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 31/94 (33%), Positives = 36/94 (38%), Gaps = 19/94 (20%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C T TS C C+ + CV C GF D H CA CH
Sbjct 472 CSTCTSGLECSSCQPPLLMRHGQCVPTCGDGF---YQDRH-------------SCAVCHE 515
Query 647 SCATCQGPALTDCLSC--PSHASLD-PVEQTCSR 677
SCA C GP CL+C P H D E +C +
Sbjct 516 SCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGK 549
Score = 36.2 bits (82), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 22/67 (33%), Positives = 26/67 (39%), Gaps = 16/67 (24%)
Query 596 CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPA 655
C C +L Q C+ C GF YS VC CH+SC C GPA
Sbjct 623 CTACSPPKALRQGHCLPRCGEGF--------YSDHG--------VCKACHSSCLACMGPA 666
Query 656 LTDCLSC 662
+ C C
Sbjct 667 PSHCTGC 673
Score = 35.0 bits (79), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 29/92 (32%), Positives = 36/92 (39%), Gaps = 17/92 (18%)
Query 579 PVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRA 638
P P +GCK EEG + Q S V P G H+ E+
Sbjct 665 PAPSHCTGCKKP---------EEGLQVEQLSDVG-IPSGECLAQCRAHFYLES------T 708
Query 639 SVCAPCHASCATCQGPALTDCLSC-PSHASLD 669
+C CH SC C G + +C C PSH LD
Sbjct 709 GICEACHQSCFRCAGKSPHNCTDCGPSHVLLD 740
>sp|P16397|SUBF_BACSU Bacillopeptidase F OS=Bacillus subtilis
(strain 168) OX=224308 GN=bpr PE=1 SV=2
Length=1433
Score = 40.8 bits (94), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 79/332 (24%), Positives = 124/332 (37%), Gaps = 61/332 (18%)
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQM-- 189
++ AWA GY G G VV+ +D G+E NHP L Y G + + ++ + Y +
Sbjct 206 IDAPKAWALGYDGTGTVVASIDTGVEWNHPALKEKYR-GYNPENPNEPENEMNWYDAVAG 264
Query 190 -----NDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD---GEVTDAVEARSLG 241
+D HGT G + +G +GVA A+ V+ G D +EA
Sbjct 265 EASPYDDLAHGTHVTGTMVGSEPDGTNQIGVAPGAKWIAVKAFSEDGGTDADILEAGEWV 324
Query 242 LNPNHIH----------IYSASWGPEDDGKTVDGPARLAEEAF-----FRGVSQGR---- 282
L P + + SWG G +D R A+ F S G
Sbjct 325 LAPKDAEGNPHPEMAPDVVNNSWG---GGSGLDEWYRDMVNAWRAADIFPEFSAGNTDLF 381
Query 283 --GGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATT 340
GG GSI N Y S T + + + + +
Sbjct 382 IPGGPGSI--------------ANPANYPESFATGATDINKKLADFSLQGPSPYDEIKPE 427
Query 341 YSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQT 400
S+ N + V Q + GTS + P + + AL +AN +L+ +M+ ++ T
Sbjct 428 ISAPGVNIRSSVP---GQTYEDGWDGTSMAGPHVSAVAALLKQANASLSVDEMEDILTST 484
Query 401 SKP-AHLNANDWATNGVGRKVSHSYGYGLLDA 431
++P D NG YG+GL++A
Sbjct 485 AEPLTDSTFPDSPNNG--------YGHGLVNA 508
>sp|P23653|PRTR_PARAQ Proteinase R OS=Parengyodontium album OX=37998
GN=PROR PE=1 SV=1
Length=387
Score = 40.0 bits (92), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 44/206 (21%), Positives = 80/206 (39%), Gaps = 33/206 (16%)
Query 23 DAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRP 82
+AQG+ + + + V++ G A+A+ A + ++ G H + + S
Sbjct 33 EAQGEMI-ADKYIVKLKEGSALASLDAA------MEKLSGKADHVYKNIFKGFAASLDEK 85
Query 83 RHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGY 142
L+ P V+++EQ D + W L+ ++
Sbjct 86 MVEVLRAHPDVEYIEQ---------DAIVNINAEQRNAPWGLARISSTSPGTSTYRYDDS 136
Query 143 TGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEV 202
G G V ++D G+E +HP+ G ++ + +D N HGT CAG +
Sbjct 137 AGQGTCVYVIDTGVEASHPEFEGRAQMVKTYYASSRD-----------GNGHGTHCAGTI 185
Query 203 AAVANNGVCGVGVAYNARIGGVRMLD 228
G GVA +I GV++L+
Sbjct 186 ------GSRTYGVAKKTQIFGVKVLN 205
>sp|Q5M7L6|RSPO2_XENTR R-spondin-2 OS=Xenopus tropicalis OX=8364
GN=rspo2 PE=1 SV=1
Length=243
Score = 39.3 bits (90), Expect = 0.080, Method: Composition-based stats.
Identities = 14/34 (41%), Positives = 19/34 (56%), Gaps = 0/34 (0%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAP 620
C + S C+ C+ GF H+ C + CP GFAP
Sbjct 101 CDSCFSRDFCIKCKSGFYSHKGQCFEECPEGFAP 134
>sp|Q8BFU0|RSPO2_MOUSE R-spondin-2 OS=Mus musculus OX=10090 GN=Rspo2
PE=1 SV=1
Length=243
Score = 39.3 bits (90), Expect = 0.095, Method: Composition-based stats.
Identities = 22/65 (34%), Positives = 26/65 (40%), Gaps = 2/65 (3%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C + S C C+ GF LH+ C CP GFAP LD E S C
Sbjct 101 CDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAP--LDETMECVEGCEVGHWSEWGTCSR 158
Query 647 SCATC 651
+ TC
Sbjct 159 NNRTC 163
>sp|Q6UXX9|RSPO2_HUMAN R-spondin-2 OS=Homo sapiens OX=9606 GN=RSPO2
PE=1 SV=2
Length=243
Score = 38.9 bits (89), Expect = 0.10, Method: Composition-based stats.
Identities = 15/34 (44%), Positives = 18/34 (53%), Gaps = 0/34 (0%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAP 620
C + S C C+ GF LH+ C CP GFAP
Sbjct 101 CDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAP 134
>sp|L8GD75|SUB3_PSED2 Subtilisin-like protease 3 OS=Pseudogymnoascus
destructans (strain ATCC MYA-4855 / 20631-21) OX=658429
GN=SP3 PE=1 SV=1
Length=404
Score = 39.7 bits (91), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 43/149 (29%), Positives = 64/149 (43%), Gaps = 29/149 (19%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYT- 143
+R+ + P V ++++ V K Y P W L ++ R N + + YT
Sbjct 94 NRISQSPHVAYVDKDV-----KVSAYDLSVRIGAP--WGLDRISHR--NGTSPGLEEYTY 144
Query 144 ----GHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
G G + I+D G+ H + G GA+F D D ++ HGT A
Sbjct 145 DSSAGGGTTIYIIDTGVYIEHVEFEGRATFGANFIPGSPDTD---------EDGHGTHVA 195
Query 200 GEVAAVANNGVCGVGVAYNARIGGVRMLD 228
G +AA AN GVA A+I VR+LD
Sbjct 196 G-IAAGAN-----FGVASKAKIIAVRVLD 218
>sp|A1XIH0|SUB6_TRIEQ Subtilisin-like protease 6 OS=Trichophyton
equinum OX=63418 GN=SUB6 PE=1 SV=1
Length=412
Score = 39.3 bits (90), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 16/109 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L+ V+ + + G G+ ++D GI+ NH D G G +F V+D D D
Sbjct 136 WGLARVSSKKAGGTTYYYDSSAGKGVTAYVIDTGIDINHEDFRGRAKWGKNF-VDDMDED 194
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE 230
N HGT AG V G G+A + V++LD E
Sbjct 195 C---------NGHGTHVAGTV------GGTKYGLAKGVSLVAVKVLDCE 228
>sp|Q3ZEJ8|SUB6_TRITO Subtilisin-like protease 6 OS=Trichophyton
tonsurans OX=34387 GN=SUB6 PE=3 SV=1
Length=412
Score = 39.3 bits (90), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 32/109 (29%), Positives = 46/109 (42%), Gaps = 16/109 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L+ V+ + + G G+ ++D GI+ NH D G G +F V+D D D
Sbjct 136 WGLARVSSKKAGGTTYYYDSSAGKGVTAYVIDTGIDINHEDFRGRAKWGKNF-VDDMDED 194
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE 230
N HGT AG V G G+A + V++LD E
Sbjct 195 C---------NGHGTHVAGTV------GGTKYGLAKGVSLVAVKVLDCE 228
>sp|Q32ZM1|RM201_RHOMI Subtilisin-like serine protease Rho m 2.0101
(Fragment) OS=Rhodotorula mucilaginosa OX=5537 PE=1 SV=1
Length=342
Score = 38.9 bits (89), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 33/123 (27%), Positives = 53/123 (43%), Gaps = 23/123 (19%)
Query 122 WYLSGVTQRDLNVKAAWAQ----GYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVND 177
W L+ ++ RD ++ Q G G+ ++D G+ +H G G + D
Sbjct 40 WGLARISHRDPLSLGSFDQYLYDSNGGTGVTSYVIDTGVNVHHEQFEGRAKWGKTIPQGD 99
Query 178 QDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML----DGEVTD 233
+D D N HGT CAG + + A GVA NA I V++L G ++D
Sbjct 100 EDED---------GNGHGTHCAGTIGSNA------YGVAKNAEIVAVKVLRSNGSGSMSD 144
Query 234 AVE 236
++
Sbjct 145 VIK 147
>sp|D4B5N1|SUB9_ARTBC Subtilisin-like protease 9 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB9
PE=3 SV=1
Length=402
Score = 38.9 bits (89), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 42/176 (24%), Positives = 68/176 (39%), Gaps = 22/176 (13%)
Query 57 LGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
LG + G F G+ S + + + R P V ++E R K D T
Sbjct 72 LGGLDGLKTTFEFEGLKGYSGAFDKRTIELISRNPAVDYVE---VDRVVKLDAI---TTQ 125
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
+ W L ++ + G GI + +D GI+ HP+ +G G + V+
Sbjct 126 RNAPSWGLGRISHKSAGSSDFVFDDSAGSGITIYGVDTGIDIKHPEFSGRATWGTN-TVD 184
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVT 232
++D D N HGT AG A G+A A + V++L+ + T
Sbjct 185 NEDTD---------QNGHGTHTAGTFAGAT------YGIAKKANVIAVKVLNAQGT 225
>sp|Q9Y749|PENC1_PENCI Subtilisin-like serine protease Pen c 1
OS=Penicillium citrinum OX=5077 PE=1 SV=1
Length=397
Score = 38.9 bits (89), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 52/229 (23%), Positives = 84/229 (37%), Gaps = 36/229 (16%)
Query 66 HFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLS 125
HF G+ + S + +P V+++E + T V P W L+
Sbjct 76 HFEINGLKGYTASFDESTAKDIANDPAVKYIEPDMIVNATANVV-----QSNVPS-WGLA 129
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPR 185
++ + + G G+V +D GI+ +H D G A + N D D
Sbjct 130 RISSKRTGTTSYTYDSTAGEGVVFYGVDTGIDISHSDFGGR----AKWGTNVVDND---- 181
Query 186 YTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML--DGEVTDA--------- 234
+ N HGT A A GVA A + V++L DG T++
Sbjct 182 --NTDGNGHGTHTASTAAG------SKYGVAKKATLVAVKVLGADGSGTNSGVISGMDWA 233
Query 235 -VEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGR 282
+A+S G N ++ + S G E D A + + F V+ G
Sbjct 234 VKDAKSRGANGK--YVMNMSLGGEFSKAVNDAAANVVKSGIFLSVAAGN 280
>sp|Q9URR2|PEN13_PENRB Subtilisin-like serine protease Pen ch
13.0101 OS=Penicillium rubens OX=1108849 PE=1 SV=1
Length=397
Score = 38.9 bits (89), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 52/229 (23%), Positives = 84/229 (37%), Gaps = 36/229 (16%)
Query 66 HFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLS 125
HF G+ + S + +P V+++E + T V P W L+
Sbjct 76 HFEINGLKGYTASFDENTAKDIANDPAVKYIEPDMIVNATANVV-----QSNVPS-WGLA 129
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPR 185
++ + + G G+V +D GI+ +H D G A + N D D
Sbjct 130 RISSKRTGTTSYTYDSTAGEGVVFYGVDTGIDISHSDFGGR----AKWGTNVVDND---- 181
Query 186 YTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML--DGEVTDA--------- 234
+ N HGT A A GVA A + V++L DG T++
Sbjct 182 --NTDGNGHGTHTASTAAG------SKYGVAKKATLVAVKVLGADGSGTNSGVISGMDWA 233
Query 235 -VEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGR 282
+A+S G N ++ + S G E D A + + F V+ G
Sbjct 234 VKDAKSRGANGK--YVMNTSLGGEFSKAVNDAAANVVKSGIFLSVAAGN 280
>sp|D4D674|SUB9_TRIVH Subtilisin-like protease 9 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB9 PE=3 SV=1
Length=397
Score = 38.9 bits (89), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 42/176 (24%), Positives = 67/176 (38%), Gaps = 22/176 (13%)
Query 57 LGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
LG + G F G+ S + + + R P V ++E R K D T
Sbjct 72 LGGLDGLKTTFEFEGLKGYSGAFDKRTIELISRNPAVDYVE---VDRVVKLDAI---TTQ 125
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
+ W L ++ + G GI + +D GI+ HP+ G G + V+
Sbjct 126 RNAPSWGLGRISHKSAGSSDFVFDDSAGSGITIYGVDTGIDIKHPEFGGRATWGTN-TVD 184
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVT 232
++D D N HGT AG A G+A A + V++L+ + T
Sbjct 185 NEDTD---------QNGHGTHTAGTFAGAT------YGIAKKANVIAVKVLNAQGT 225
>sp|G1X8P8|SPAZ_ARTOA Cuticle-degrading serine protease OS=Arthrobotrys
oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491)
OX=756982 PE=1 SV=1
Length=409
Score = 38.9 bits (89), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 40/158 (25%), Positives = 58/158 (37%), Gaps = 25/158 (16%)
Query 49 ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRD 108
AR HG G + F G + + P+V ++EQ T
Sbjct 74 ARAHGV-------GRKFRFSSTGFNGYVGGFDKATLQEILNSPEVDYVEQD-----TVVT 121
Query 109 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYT--GHGIVVSILDDGIEKNHPDLAG- 165
Y E TD W L ++ D + + T G G V ++D GI +H +
Sbjct 122 TYAEQTD----STWGLDRISHEDYSAPYTYEYDETAAGAGTTVYVIDTGIRISHDEFQTV 177
Query 166 NYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVA 203
N A++ N D T + N HGT CAG +A
Sbjct 178 NGSSRATWGFNSVDK------TDSDGNGHGTHCAGTIA 209
>sp|G3FNQ9|SPAZ_ORBOL Cuticle-degrading serine protease OS=Orbilia
oligospora OX=2813651 PE=1 SV=2
Length=426
Score = 38.5 bits (88), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 40/158 (25%), Positives = 58/158 (37%), Gaps = 25/158 (16%)
Query 49 ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRD 108
AR HG G + F G + + P+V ++EQ T
Sbjct 74 ARAHGV-------GRKFRFSSTGFNGYVGGFDKATLQEILNSPEVDYVEQD-----TVVT 121
Query 109 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYT--GHGIVVSILDDGIEKNHPDLAG- 165
Y E TD W L ++ D + + T G G V ++D GI +H +
Sbjct 122 TYAEQTD----STWGLDRISHEDYSAPYTYEYDETAAGAGTTVYVIDTGIRISHDEFQTV 177
Query 166 NYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVA 203
N A++ N D T + N HGT CAG +A
Sbjct 178 NGSSRATWGFNSVDK------TDSDGNGHGTHCAGTIA 209
>sp|C5PCX1|SUB7B_COCP7 Subtilisin-like protease CPC735_015300
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_015300
PE=3 SV=1
Length=398
Score = 37.4 bits (85), Expect = 0.49, Method: Compositional matrix adjust.
Identities = 36/142 (25%), Positives = 59/142 (42%), Gaps = 22/142 (15%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ + P V ++E R T+ + ++P P W L V+ ++ G G
Sbjct 98 ISQSPDVAFIEHDHVVRLTE--LVEQPDAPT----WGLGRVSHQEPGNMDYVYDDTAGDG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ +D G++ HPD G G++ V+D D D N HGT G + ++
Sbjct 152 VWAYDIDTGVDIEHPDFEGRAVWGSNH-VDDDDTDG---------NGHGTHVGGTIGSLT 201
Query 207 NNGVCGVGVAYNARIGGVRMLD 228
GVA RI V++LD
Sbjct 202 ------YGVAKKVRIIAVKVLD 217
>sp|E4V2V9|SUB7_ARTGP Subtilisin-like protease 7 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB7
PE=3 SV=1
Length=400
Score = 37.4 bits (85), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 34/144 (24%), Positives = 59/144 (41%), Gaps = 22/144 (15%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
+ + + V+++E R + + P W L+ V ++ + G
Sbjct 99 NEIAKRADVKYIE-----RDARVQINAIEMQDNVPS-WGLARVGSKEPGGTTYYYDSSAG 152
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G+ ++D G + H + +G G +F V+D D M+ N HGT +G VA
Sbjct 153 QGVTAYVIDTGTDIKHEEFSGRATWGGNF-VDDID---------MDCNGHGTHVSGTVAG 202
Query 205 VANNGVCGVGVAYNARIGGVRMLD 228
GVA A + GV++LD
Sbjct 203 TK------FGVAKKANVVGVKVLD 220
>sp|E4V4J8|SUB6_ARTGP Subtilisin-like protease 6 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB6
PE=3 SV=1
Length=408
Score = 37.0 bits (84), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 37/156 (24%), Positives = 62/156 (40%), Gaps = 22/156 (14%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ V ++E+ + T + Q+ P W L+ V ++ + G G
Sbjct 103 ISNHDDVDFIERDTVVKATA--ITQQDNVP----SWGLARVGSKEAGGSTYYYDDTAGKG 156
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ I+D GI+ +H D G G +F V+ D D N HG+ AG V
Sbjct 157 VTAYIIDTGIDIHHGDFGGRAKWGKNF-VDKMDEDC---------NGHGSHVAGTV---- 202
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGL 242
G GVA + V++LD E + + +G+
Sbjct 203 --GGTKFGVAKGVNLVAVKVLDCEGSGSNSGVIMGM 236
>sp|D4DIS6|SUB10_TRIVH Subtilisin-like protease 10 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB10 PE=3 SV=1
Length=522
Score = 37.0 bits (84), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 37/117 (32%), Positives = 54/117 (46%), Gaps = 21/117 (18%)
Query 114 TDPKFPQQWYLSGVTQRDL-NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS 172
T PK P W L ++ + N + +G G+ VV ++D GI+ HP+ G GA+
Sbjct 121 TQPKAPN-WGLGRLSNSNPGNTDYTYDEGAGGN-AVVYVIDSGIDTMHPEFQGRATWGAN 178
Query 173 F-DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD 228
F D N+ D HGT CAG + +V GVA A + V++LD
Sbjct 179 FIDKNNVD-----------CWGHGTHCAGIIGSVT------FGVAKRAAMIAVKVLD 218
>sp|C5P5Q3|SUB9_COCP7 Subtilisin-like protease CPC735_033790 OS=Coccidioides
posadasii (strain C735) OX=222929 GN=CPC735_033790
PE=3 SV=1
Length=399
Score = 36.6 bits (83), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 16/100 (16%)
Query 144 GHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVA 203
G GI + +D GI+ HP+ G G + ++ND + D +N HGT AG A
Sbjct 150 GRGITIYGVDTGIDIRHPEFEGRATWGTN-EINDVNQD---------ENGHGTHTAGTFA 199
Query 204 AVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN 243
GVA A I V++L+ E + + G+N
Sbjct 200 G------RNFGVAKRANIVAVKVLNAEGSGSTSGIISGIN 233
>sp|C5FJA5|SUB7_ARTOC Subtilisin-like protease 7 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB7
PE=3 SV=1
Length=400
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 36/144 (25%), Positives = 58/144 (40%), Gaps = 22/144 (15%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
+++ + V+++E R R T+ W L+ V R+ + G
Sbjct 99 NQIAKHSDVKYIE------RDARVQINAITEQDNVPSWGLARVGSREAGGSTYYYDSTAG 152
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G I+D G + H + G G++F V+D D M+ N HGT +G V
Sbjct 153 EGSTAYIIDTGTDIEHEEFEGRATWGSNF-VDDMD---------MDCNGHGTHVSGTV-- 200
Query 205 VANNGVCGVGVAYNARIGGVRMLD 228
G GVA + I V++LD
Sbjct 201 ----GGATFGVAKKSNIVAVKVLD 220
>sp|P9WEW3|PCH13_PENRB Subtilisin-like serine protease Pen ch
13 OS=Penicillium rubens OX=1108849 PE=1 SV=1
Length=398
Score = 36.2 bits (82), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 42/171 (25%), Positives = 63/171 (37%), Gaps = 24/171 (14%)
Query 66 HFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLS 125
HF G+ S S + +P V+++E + T V + W LS
Sbjct 76 HFDINGMKGYSASFDDRTVKDIASDPTVKYVEPDMVVNATANVVQRNA------PSWGLS 129
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPR 185
++ + G GIV+ +D GI+ H D G A + N D D
Sbjct 130 RISSKKSGATDYVYDSTAGEGIVIYGVDTGIDIGHADFGGR----AEWGTNTADND---- 181
Query 186 YTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML--DGEVTDA 234
+ N HGT A A GVA A + V++L DG T++
Sbjct 182 --DTDGNGHGTHTASTAAG------SKFGVAKKASVVAVKVLGADGSGTNS 224
>sp|P9WEW4|PCH13_PENCH Subtilisin-like serine protease EN45_076310
OS=Penicillium chrysogenum OX=5076 GN=EN45_076310 PE=3
SV=1
Length=398
Score = 36.2 bits (82), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 42/171 (25%), Positives = 63/171 (37%), Gaps = 24/171 (14%)
Query 66 HFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLS 125
HF G+ S S + +P V+++E + T V + W LS
Sbjct 76 HFDINGMKGYSASFDDRTVKDIASDPTVKYVEPDMVVNATANVVQRNA------PSWGLS 129
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPR 185
++ + G GIV+ +D GI+ H D G A + N D D
Sbjct 130 RISSKKSGATDYVYDSTAGEGIVIYGVDTGIDIGHADFGGR----AEWGTNTADND---- 181
Query 186 YTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML--DGEVTDA 234
+ N HGT A A GVA A + V++L DG T++
Sbjct 182 --DTDGNGHGTHTASTAAG------SKFGVAKKASVVAVKVLGADGSGTNS 224
>sp|P28842|SUBT_BACS9 Subtilisin OS=Bacillus sp. (strain TA39)
OX=29336 GN=sub1 PE=1 SV=1
Length=420
Score = 36.2 bits (82), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 29/89 (33%), Positives = 39/89 (44%), Gaps = 14/89 (16%)
Query 144 GHGIVVSILDDGIEKNHPDLAGNYDPGASFDV-----NDQDPDPQPRYTQMNDNRHGTRC 198
G GI +++LD G+ NHPDL N + F V N+ D Q HGT
Sbjct 136 GGGINIAVLDTGVNTNHPDLRNNVEQCKDFTVGTTYTNNSCTDRQG---------HGTHV 186
Query 199 AGEVAAVANNGVCGVGVAYNARIGGVRML 227
AG A G GVA +A + ++L
Sbjct 187 AGSALADGGTGNGVYGVAPDADLWAYKVL 215
>sp|Q1DFT5|POPC_MYXXD Subtilisin-like protease PopC OS=Myxococcus
xanthus (strain DK1622) OX=246197 GN=popC PE=1 SV=1
Length=475
Score = 35.8 bits (81), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 27/98 (28%), Positives = 46/98 (47%), Gaps = 6/98 (6%)
Query 119 PQQWYLSGVTQRD----LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFD 174
P+ +S + +R+ V A AQG G G+++ ILD G++ +HP+ A
Sbjct 163 PRNRGMSSLAEREWPDECGVPLAHAQGIRGAGVMLGILDTGVDADHPEHAARVIQFRYVS 222
Query 175 VNDQDP-DPQPRYTQMNDNRHGTRCAGEVAAVANNGVC 211
+ P +P + + HGT G +AA ++GV
Sbjct 223 LFPNSPHNPARDIRGFDPDGHGTHVCG-IAAGVHHGVA 259
>sp|Q9UTS0|PSP3_SCHPO Subtilase-type proteinase psp3 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=psp3
PE=2 SV=1
Length=451
Score = 35.8 bits (81), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 26/97 (27%), Positives = 43/97 (44%), Gaps = 19/97 (20%)
Query 144 GHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVA 203
G G+ ++D GI H D G GA+ + + D D+ HGT AG +A
Sbjct 196 GEGVTAYVIDTGINIEHQDFQGRATWGATIPTGEGEVD---------DHGHGTHVAGTIA 246
Query 204 AVANNGVCGVGVAYNARIGGVRML----DGEVTDAVE 236
GV+ NA++ V+++ G V+D ++
Sbjct 247 GKT------FGVSKNAKLVAVKVMRADGTGTVSDIIK 277
>sp|Q5UE90|RSPO2_XENLA R-spondin-2 OS=Xenopus laevis OX=8355 GN=rspo2
PE=2 SV=1
Length=243
Score = 35.4 bits (80), Expect = 1.7, Method: Composition-based stats.
Identities = 13/34 (38%), Positives = 18/34 (53%), Gaps = 0/34 (0%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAP 620
C + S C+ C+ GF + C + CP GFAP
Sbjct 101 CDSCFSRDFCIKCKSGFYSLKGQCFEECPEGFAP 134
>sp|Q92GM6|TGT_RICCN Queuine tRNA-ribosyltransferase OS=Rickettsia
conorii (strain ATCC VR-613 / Malish 7) OX=272944 GN=tgt
PE=3 SV=1
Length=361
Score = 35.8 bits (81), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 26/121 (21%), Positives = 49/121 (40%), Gaps = 17/121 (14%)
Query 485 EHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPS 544
+H +AR + G++ P+GTR T+ A P + G D T+ P+
Sbjct 11 QHKKARSGIIVTAHGEMRTPAFMPVGTRGTVKAMLPESVAETG-ADILLGNTYHLMLQPT 69
Query 545 GEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFS 604
E ++++ + N+ P+ +S G + ++ S+ C + EEG S
Sbjct 70 AERIVQLGGLHKFMNWDK----------------PILTDSGGFQVMSLSKLCKITEEGVS 113
Query 605 L 605
Sbjct 114 F 114
>sp|C3PLJ4|TGT_RICAE Queuine tRNA-ribosyltransferase OS=Rickettsia
africae (strain ESF-5) OX=347255 GN=tgt PE=3 SV=1
Length=361
Score = 35.8 bits (81), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 26/121 (21%), Positives = 49/121 (40%), Gaps = 17/121 (14%)
Query 485 EHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPS 544
+H +AR + G++ P+GTR T+ A P + G D T+ P+
Sbjct 11 QHKKARSGIIVTAHGEMRTPAFMPVGTRGTVKAMLPESVAETG-ADILLGNTYHLMLQPT 69
Query 545 GEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFS 604
E ++++ + N+ P+ +S G + ++ S+ C + EEG S
Sbjct 70 AERIVQLGGLHKFMNWDK----------------PILTDSGGFQVMSLSKLCKITEEGVS 113
Query 605 L 605
Sbjct 114 F 114
>sp|A8GTF4|TGT_RICRS Queuine tRNA-ribosyltransferase OS=Rickettsia
rickettsii (strain Sheila Smith) OX=392021 GN=tgt PE=3
SV=1
Length=361
Score = 35.4 bits (80), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 26/121 (21%), Positives = 49/121 (40%), Gaps = 17/121 (14%)
Query 485 EHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPS 544
+H +AR + G++ P+GTR T+ A P + G D T+ P+
Sbjct 11 QHKKARSGIIVTAHGEMRTPAFMPVGTRGTVKAMLPESVAETG-ADILLGNTYHLMLQPT 69
Query 545 GEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFS 604
E ++++ + N+ P+ +S G + ++ S+ C + EEG S
Sbjct 70 AERIVQLGGLHKFMNWDK----------------PILTDSGGFQVMSLSKLCKITEEGVS 113
Query 605 L 605
Sbjct 114 F 114
>sp|B0BUZ2|TGT_RICRO Queuine tRNA-ribosyltransferase OS=Rickettsia
rickettsii (strain Iowa) OX=452659 GN=tgt PE=3 SV=1
Length=361
Score = 35.4 bits (80), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 26/121 (21%), Positives = 49/121 (40%), Gaps = 17/121 (14%)
Query 485 EHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPS 544
+H +AR + G++ P+GTR T+ A P + G D T+ P+
Sbjct 11 QHKKARSGIIVTAHGEMRTPAFMPVGTRGTVKAMLPESVAETG-ADILLGNTYHLMLQPT 69
Query 545 GEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFS 604
E ++++ + N+ P+ +S G + ++ S+ C + EEG S
Sbjct 70 AERIVQLGGLHKFMNWDK----------------PILTDSGGFQVMSLSKLCKITEEGVS 113
Query 605 L 605
Sbjct 114 F 114
>sp|C4K0T2|TGT_RICPU Queuine tRNA-ribosyltransferase OS=Rickettsia
peacockii (strain Rustic) OX=562019 GN=tgt PE=3 SV=1
Length=361
Score = 35.4 bits (80), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 26/121 (21%), Positives = 49/121 (40%), Gaps = 17/121 (14%)
Query 485 EHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPS 544
+H +AR + G++ P+GTR T+ A P + G D T+ P+
Sbjct 11 QHKKARSGIIVTAHGEMRTPAFMPVGTRGTVKAMLPESVAETG-ADILLGNTYHLMLQPT 69
Query 545 GEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFS 604
E ++++ + N+ P+ +S G + ++ S+ C + EEG S
Sbjct 70 AERIVQLGGLHKFMNWDK----------------PILTDSGGFQVMSLSKLCKITEEGVS 113
Query 605 L 605
Sbjct 114 F 114
>sp|D4APA9|SUB7_ARTBC Subtilisin-like protease 7 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB7
PE=1 SV=2
Length=420
Score = 35.4 bits (80), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 34/144 (24%), Positives = 60/144 (42%), Gaps = 22/144 (15%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
+ + + V+++E+ R + Q+ P W L+ V ++ + G G
Sbjct 99 NEISKRADVKYIERDA--RVQINAIEQQDNVP----SWGLARVGSKEPGGTTYYYDGTAG 152
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G ++D G + H + G GA+F V+D D M+ N HGT +G +
Sbjct 153 EGSTAYVIDTGTDIQHEEFEGRATWGANF-VDDMD---------MDCNGHGTHVSGTI-- 200
Query 205 VANNGVCGVGVAYNARIGGVRMLD 228
G GVA + + V++LD
Sbjct 201 ----GGKTFGVAKKSNVVAVKVLD 220
>sp|D4CZQ4|SUB7_TRIVH Subtilisin-like protease 7 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB7 PE=3 SV=2
Length=420
Score = 35.4 bits (80), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 33/144 (23%), Positives = 59/144 (41%), Gaps = 22/144 (15%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
+ + + V+++E+ R + Q+ P W L+ V ++ + G G
Sbjct 99 NEISKRADVKYIERDA--RVQINAIEQQDNVPS----WGLARVGSKEPGGTTYYYDGTAG 152
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G ++D G + H + G GA+F V+D D M+ N HGT +G +
Sbjct 153 EGSTAYVIDTGTDIQHEEFEGRATWGANF-VDDMD---------MDCNGHGTHVSGTIGG 202
Query 205 VANNGVCGVGVAYNARIGGVRMLD 228
GVA + + V++LD
Sbjct 203 KT------FGVAKKSNVVAVKVLD 220
>sp|C5FXZ6|SUB4_ARTOC Subtilisin-like protease 4 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB4
PE=3 SV=1
Length=399
Score = 35.4 bits (80), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 30/106 (28%), Positives = 42/106 (40%), Gaps = 16/106 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L V+ R ++ G G+ + +D GI+ NH D G A + N D D
Sbjct 129 WGLGRVSHRQAGIRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGR----ARWGTNTADRD 184
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
R+ HGT A A G+A NA I V++L
Sbjct 185 NADRHG------HGTHTASTFAGTT------YGIAKNANIVAVKVL 218
>sp|B8XGQ7|SUB4_TRITO Subtilisin-like protease 4 OS=Trichophyton
tonsurans OX=34387 GN=SUB4 PE=3 SV=1
Length=399
Score = 35.0 bits (79), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 31/106 (29%), Positives = 42/106 (40%), Gaps = 16/106 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L V+ R + G G+ + +D GI+ NH D G A + N D D
Sbjct 129 WGLGRVSHRQAGSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGR----ARWGTNTADRD 184
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
R+ HGT A A A G+A NA I V++L
Sbjct 185 NADRHG------HGTHTASTFAGTA------YGIAKNANIVAVKVL 218
>sp|A7UKV6|SUB4_TRIEQ Subtilisin-like protease 4 (Fragment) OS=Trichophyton
equinum OX=63418 GN=SUB4 PE=3 SV=1
Length=394
Score = 35.0 bits (79), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 31/106 (29%), Positives = 42/106 (40%), Gaps = 16/106 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L V+ R + G G+ + +D GI+ NH D G A + N D D
Sbjct 127 WGLGRVSHRQAGSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGR----ARWGTNTADRD 182
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
R+ HGT A A A G+A NA I V++L
Sbjct 183 NADRHG------HGTHTASTFAGTA------YGIAKNANIVAVKVL 216
>sp|R4IR27|ASES_SARSR Subtilisin-like serine protease AsES OS=Sarocladium
strictum OX=5046 GN=AsES PE=1 SV=1
Length=388
Score = 35.0 bits (79), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 34/141 (24%), Positives = 52/141 (37%), Gaps = 24/141 (17%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
L+ +P V ++EQ V + W L+ ++ R G G
Sbjct 87 LRDDPSVDFIEQDAI-------VTLAAYTTQASAPWGLARISTRQRGPTGYTYDDSAGAG 139
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I+D GI+ NHP+ G S+ ++ D N HGT AG +
Sbjct 140 TCSYIIDTGIQANHPNFGGRAFQLVSYQGSNAD-----------GNGHGTHVAGTI---- 184
Query 207 NNGVCGVGVAYNARIGGVRML 227
G GVA + GV++L
Sbjct 185 --GSTTYGVAKRTTLLGVKVL 203
>sp|D4D6Q4|SUB4_TRIVH Subtilisin-like protease 4 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB4 PE=3 SV=1
Length=399
Score = 35.0 bits (79), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 31/106 (29%), Positives = 42/106 (40%), Gaps = 16/106 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L V+ R + G G+ + +D GI+ NH D G A + N D D
Sbjct 129 WGLGRVSHRQAGSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGR----ARWGTNTADRD 184
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
R+ HGT A A A G+A NA I V++L
Sbjct 185 NADRHG------HGTHTASTFAGTA------YGIAKNANIVAVKVL 218
>sp|Q5VJ74|SUB4_TRIVC Subtilisin-like protease 4 OS=Trichophyton
verrucosum OX=63417 GN=SUB4 PE=3 SV=1
Length=399
Score = 35.0 bits (79), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 31/106 (29%), Positives = 42/106 (40%), Gaps = 16/106 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L V+ R + G G+ + +D GI+ NH D G A + N D D
Sbjct 129 WGLGRVSHRQAGSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGR----ARWGTNTADRD 184
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
R+ HGT A A A G+A NA I V++L
Sbjct 185 NADRHG------HGTHTASTFAGTA------YGIAKNANIVAVKVL 218
>sp|Q64K33|SUB4_ARTBE Subtilisin-like protease 4 OS=Arthroderma
benhamiae OX=63400 GN=SUB4 PE=3 SV=1
Length=399
Score = 35.0 bits (79), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 31/106 (29%), Positives = 42/106 (40%), Gaps = 16/106 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L V+ R + G G+ + +D GI+ NH D G A + N D D
Sbjct 129 WGLGRVSHRQAGSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGR----ARWGTNTADRD 184
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
R+ HGT A A A G+A NA I V++L
Sbjct 185 NADRHG------HGTHTASTFAGTA------YGIAKNANIVAVKVL 218
>sp|D4AXW3|SUB4_ARTBC Subtilisin-like protease 4 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB4
PE=1 SV=2
Length=399
Score = 35.0 bits (79), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 31/106 (29%), Positives = 42/106 (40%), Gaps = 16/106 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L V+ R + G G+ + +D GI+ NH D G A + N D D
Sbjct 129 WGLGRVSHRQAGSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGR----ARWGTNTADRD 184
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
R+ HGT A A A G+A NA I V++L
Sbjct 185 NADRHG------HGTHTASTFAGTA------YGIAKNANIVAVKVL 218
>sp|Q69F35|SUB4_TRIRU Subtilisin-like protease 4 OS=Trichophyton
rubrum OX=5551 GN=SUB4 PE=1 SV=1
Length=399
Score = 35.0 bits (79), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 31/106 (29%), Positives = 42/106 (40%), Gaps = 16/106 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L V+ R + G G+ + +D GI+ NH D G A + N D D
Sbjct 129 WGLGRVSHRQAGSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGR----ARWGTNTADRD 184
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
R+ HGT A A A G+A NA I V++L
Sbjct 185 NADRHG------HGTHTASTFAGTA------YGIAKNANIVAVKVL 218
>sp|Q64K36|SUB7_ARTBE Subtilisin-like protease 7 OS=Arthroderma
benhamiae OX=63400 GN=SUB7 PE=1 SV=1
Length=400
Score = 35.0 bits (79), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 33/144 (23%), Positives = 59/144 (41%), Gaps = 22/144 (15%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
+ + + V+++E+ R + Q+ P W L+ V ++ + G G
Sbjct 99 NEISKRADVKYIERDA--RVQINAIEQQDNVP----SWGLARVGSKEPGGTTYYYDGTAG 152
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G ++D G + H + G GA+F V+D D M+ N HGT +G +
Sbjct 153 EGSTAYVIDTGTDIQHEEFEGRATWGANF-VDDMD---------MDCNGHGTHVSGTIGG 202
Query 205 VANNGVCGVGVAYNARIGGVRMLD 228
GVA + + V++LD
Sbjct 203 KT------FGVAKKSNVVAVKVLD 220
>sp|P15293|P2P_LACLC PII-type proteinase OS=Lactococcus lactis
subsp. cremoris OX=1359 GN=prt PE=3 SV=1
Length=1902
Score = 35.4 bits (80), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 15/32 (47%), Positives = 21/32 (66%), Gaps = 1/32 (3%)
Query 133 NVKAAWAQ-GYTGHGIVVSILDDGIEKNHPDL 163
NV+A W+ Y G G VVS++D GI+ H D+
Sbjct 196 NVQAVWSNYKYKGEGTVVSVIDSGIDPTHKDM 227
>sp|P16271|P1P_LACLC PI-type proteinase OS=Lactococcus lactis
subsp. cremoris OX=1359 GN=prtP PE=3 SV=1
Length=1902
Score = 35.4 bits (80), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 15/32 (47%), Positives = 21/32 (66%), Gaps = 1/32 (3%)
Query 133 NVKAAWAQ-GYTGHGIVVSILDDGIEKNHPDL 163
NV+A W+ Y G G VVS++D GI+ H D+
Sbjct 196 NVQAVWSNYKYKGEGTVVSVIDSGIDPTHKDM 227
>sp|P15292|P3P_LACLS PIII-type proteinase OS=Lactococcus lactis
subsp. cremoris (strain SK11) OX=272622 GN=prtP PE=1 SV=2
Length=1962
Score = 35.4 bits (80), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 15/32 (47%), Positives = 21/32 (66%), Gaps = 1/32 (3%)
Query 133 NVKAAWAQ-GYTGHGIVVSILDDGIEKNHPDL 163
NV+A W+ Y G G VVS++D GI+ H D+
Sbjct 196 NVQAVWSNYKYKGEGTVVSVIDSGIDPTHKDM 227
>sp|Q0WUG6|SBT61_ARATH Subtilisin-like protease SBT6.1 OS=Arabidopsis
thaliana OX=3702 GN=SBT6.1 PE=1 SV=1
Length=1038
Score = 35.4 bits (80), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 62/253 (25%), Positives = 104/253 (41%), Gaps = 34/253 (13%)
Query 138 WAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNR-HGT 196
W +GYTG + ++I D GI +HP + N + D +NDN HGT
Sbjct 197 WKKGYTGAKVKMAIFDTGIRADHPHFRKIKE-----RTNWTNED------TLNDNLGHGT 245
Query 197 RCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDA-VEARSLGLNPNHIHIYSASWG 255
AG +A N C +G A + I R+ TDA V S L+ + Y+ +
Sbjct 246 FVAGVIA--GRNPEC-LGFASDTEIYAFRVF----TDAQVSYTSWFLDAFN---YAIATD 295
Query 256 PEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTL 315
+ ++ GP L + F V + I V A GN G + + N + + +
Sbjct 296 MDVLNLSIGGPDYL-DLPFVEKVWEITAS-NIIMVSAIGNDGPLYGTLNNPADQSDV--I 351
Query 316 SISSATQFGNVPWYSEACSSTLATTYSSGNQNE------KQIVTTDLRQKCTESHTGTSA 369
+ ++ +S ST + G + I+ + + C +S +GTS
Sbjct 352 GVGGIDNDDHIASFSSRGMSTWELPHGYGRVKPDVVAYGRDIMGSKISTGC-KSLSGTSV 410
Query 370 SAPLAAGIIALTL 382
++P+ AGI+ L +
Sbjct 411 ASPVVAGIVCLLV 423
>sp|A9QY38|SBT4_LOTJA Subtilisin-like protease 4 OS=Lotus japonicus
OX=34305 GN=SBTM4 PE=2 SV=1
Length=755
Score = 35.0 bits (79), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 40/149 (27%), Positives = 59/149 (40%), Gaps = 31/149 (21%)
Query 129 QRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPR--- 185
Q+D V W + G G+++ +LD GI HP + DV P P+ +
Sbjct 132 QQDTGV---WKESNFGKGVIIGVLDSGITPGHPSFS---------DVGIPPPPPKWKGRC 179
Query 186 ---YTQMNDNRHGTRCAGEVAAVANNGVC--------GVGVAYNARIGGVRMLDGEVTDA 234
T N+ G R A +AA A NG G G + G + EV
Sbjct 180 DLNVTACNNKLIGAR-AFNLAAEAMNGKKAEAPIDEDGHGTHTASTAAGAFVNYAEVLGN 238
Query 235 VEARSLGLNPN-HIHIYSASWG---PEDD 259
+ + G+ P+ H+ IY +G PE D
Sbjct 239 AKGTAAGMAPHAHLAIYKVCFGEDCPESD 267
>sp|C5FQI3|SUB6_ARTOC Subtilisin-like protease 6 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB6
PE=3 SV=1
Length=406
Score = 35.0 bits (79), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 34/115 (30%), Positives = 48/115 (42%), Gaps = 16/115 (14%)
Query 114 TDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
T+ K W LS ++ ++ + G G I+D GI+ N+ D G G +F
Sbjct 123 TEQKDVPSWGLSRLSTKEPGGTTYFYDESAGEGTTAYIVDTGIDVNNGDFGGRAKWGNNF 182
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD 228
V+ QD D N HGT AG V G GVA + V++LD
Sbjct 183 -VDHQDTDC---------NGHGTHVAGTV------GGKNFGVAKKTNLIAVKVLD 221
>sp|Q5VJ71|SUB7_TRIVC Subtilisin-like protease 7 OS=Trichophyton
verrucosum OX=63417 GN=SUB7 PE=3 SV=1
Length=400
Score = 35.0 bits (79), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 33/144 (23%), Positives = 59/144 (41%), Gaps = 22/144 (15%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
+ + + V+++E+ R + Q+ P W L+ V ++ + G G
Sbjct 99 NEISKRADVKYIERDA--RVQINAIEQQDNVP----SWGLARVGSKEPGGTTYYYDGTAG 152
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G ++D G + H + G GA+F V+D D M+ N HGT +G +
Sbjct 153 EGSTAYVIDTGTDIQHEEFEGRATWGANF-VDDMD---------MDCNGHGTHVSGTIGG 202
Query 205 VANNGVCGVGVAYNARIGGVRMLD 228
GVA + + V++LD
Sbjct 203 KT------FGVAKKSNVVAVKVLD 220
>sp|Q02470|P2P_LACPA PII-type proteinase OS=Lacticaseibacillus
paracasei OX=1597 GN=prtP PE=1 SV=1
Length=1902
Score = 35.0 bits (79), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 15/32 (47%), Positives = 21/32 (66%), Gaps = 1/32 (3%)
Query 133 NVKAAWAQ-GYTGHGIVVSILDDGIEKNHPDL 163
NV+A W+ Y G G VVS++D GI+ H D+
Sbjct 196 NVQAVWSNYKYKGEGTVVSVIDTGIDPTHKDM 227
>sp|P72186|PLS_PYRFU Pyrolysin OS=Pyrococcus furiosus (strain
ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) OX=186497 GN=pls PE=1
SV=2
Length=1398
Score = 34.7 bits (78), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 24/93 (26%), Positives = 47/93 (51%), Gaps = 12/93 (13%)
Query 77 LSPHRPRHSRLQREPQVQWLEQQV--AKRRTKRDVY-QEPT-DPK-FPQQWYLSGVTQRD 131
+ P + + + WL ++V + ++DV +EP+ +PK + W ++ +
Sbjct 105 IKPEKVKELNYISSLEKAWLNREVKLSPPIVEKDVKTKEPSLEPKMYNSTWVINAL---- 160
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLA 164
+ GY G G+VV++LD G++ NHP L+
Sbjct 161 ---QFIQEFGYDGSGVVVAVLDTGVDPNHPFLS 190
>sp|Q4G063|CREL2_RAT Protein disulfide isomerase Creld2 OS=Rattus
norvegicus OX=10116 GN=Creld2 PE=1 SV=1
Length=349
Score = 34.3 bits (77), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 24/91 (26%), Positives = 38/91 (42%), Gaps = 10/91 (11%)
Query 639 SVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQP------- 691
S+C C SC TC GP+ DC+ C VE C + + E+PP +
Sbjct 191 SICLACDESCKTCSGPSNKDCVQC--EVGWARVEDACVDVDECAAETPPCSEAQYCENVN 248
Query 692 -PRLPPEVEAGQRLRAGLLPSHLPEVVAGLS 721
+ E ++ G P++ E +AG +
Sbjct 249 GSYICEECDSTCVGCTGKGPANCKECIAGYT 279
>sp|Q64K31|SUB6_ARTBE Subtilisin-like protease 6 OS=Arthroderma
benhamiae OX=63400 GN=SUB6 PE=3 SV=1
Length=412
Score = 34.3 bits (77), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 16/109 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L+ V + + G G+ I+D GI+ +H D G G +F +D D D
Sbjct 136 WGLARVGSKQAGGTTYYYDPSAGKGVRAYIIDTGIDTDHKDFGGRAKWGKNF-ADDMDQD 194
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE 230
N HGT AG V G G+A + + V++LD E
Sbjct 195 C---------NGHGTHVAGTV------GGTQYGLAKSVSLIAVKVLDCE 228
>sp|D4ALV9|SUB6_ARTBC Subtilisin-like protease 6 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB6
PE=2 SV=1
Length=412
Score = 34.3 bits (77), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 45/109 (41%), Gaps = 16/109 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L+ V + + G G+ I+D GI+ +H D G G +F +D D D
Sbjct 136 WGLARVGSKQAGGTTYYYDPSAGKGVRAYIIDTGIDTDHKDFGGRAKWGKNF-ADDMDQD 194
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE 230
N HGT AG V G G+A + + V++LD E
Sbjct 195 C---------NGHGTHVAGTV------GGTQYGLAKSVSLIAVKVLDCE 228
>sp|B6VA86|SUB3_TRIEQ Subtilisin-like protease 3 OS=Trichophyton
equinum OX=63418 GN=SUB3 PE=3 SV=1
Length=397
Score = 34.3 bits (77), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 34/114 (30%), Positives = 44/114 (39%), Gaps = 17/114 (15%)
Query 114 TDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
T P P W L V+ R + G GI + +D GI+ HP+ AG G +
Sbjct 120 TQPNAPT-WGLGRVSHRAPGNRDFVYDSSAGQGITIYGVDTGIDIRHPEFAGRIRWGTNT 178
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
ND + N HGT AG A GVA A I V++L
Sbjct 179 VDND----------NTDGNGHGTHTAGTFAGTT------YGVAKKANIVAVKVL 216
>sp|E4UN97|SUB3_ARTGP Subtilisin-like protease 3 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB3
PE=3 SV=1
Length=397
Score = 34.3 bits (77), Expect = 4.4, Method: Compositional matrix adjust.
Identities = 33/114 (29%), Positives = 44/114 (39%), Gaps = 17/114 (15%)
Query 114 TDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
T P P W L V+ + K G G+ + +D GI+ NHP+ G G +
Sbjct 120 TQPNAPT-WGLGRVSHKAKGNKDFVYDSSAGQGVTIYGVDTGIDINHPEFRGRIRWGTNT 178
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
ND + N HGT AG A GVA A I V++L
Sbjct 179 VDND----------NTDGNGHGTHTAGTFAGTT------YGVAKKANIVAVKVL 216
>sp|B8XGQ6|SUB3_TRITO Subtilisin-like protease 3 OS=Trichophyton
tonsurans OX=34387 GN=SUB3 PE=3 SV=1
Length=397
Score = 34.3 bits (77), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 34/114 (30%), Positives = 44/114 (39%), Gaps = 17/114 (15%)
Query 114 TDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
T P P W L V+ R + G GI + +D GI+ HP+ AG G +
Sbjct 120 TQPNAPT-WGLGRVSHRAPGNRDFVYDSSAGQGITIYGVDTGIDIRHPEFAGRIRWGTNT 178
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
ND + N HGT AG A GVA A I V++L
Sbjct 179 VDND----------NTDGNGHGTHTAGTFAGTT------YGVAKKANIVAVKVL 216
>sp|D4DLA2|SUB3_TRIVH Subtilisin-like protease 3 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB3 PE=3 SV=1
Length=397
Score = 34.3 bits (77), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 38/141 (27%), Positives = 55/141 (39%), Gaps = 22/141 (16%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ ++ +V ++E R K + T P P W L V+ + K G G
Sbjct 98 ILKDDKVNYVEHD---RVVK--LAALTTQPNAPT-WGLGRVSHKAPGNKDFVYDSSAGQG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I + +D GI+ HP+ AG G + ND + N HGT AG A
Sbjct 152 ITIYGVDTGIDIRHPEFAGRIRWGTNTVDND----------NTDGNGHGTHTAGTFAGTT 201
Query 207 NNGVCGVGVAYNARIGGVRML 227
GVA A I V++L
Sbjct 202 ------YGVAKKANIVAVKVL 216
>sp|Q5VJ75|SUB3_TRIVC Subtilisin-like protease 3 OS=Trichophyton
verrucosum OX=63417 GN=SUB3 PE=3 SV=1
Length=397
Score = 34.3 bits (77), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 38/141 (27%), Positives = 55/141 (39%), Gaps = 22/141 (16%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ ++ +V ++E R K + T P P W L V+ + K G G
Sbjct 98 ILKDDKVNYVEHD---RVVK--LAALTTQPNAPT-WGLGRVSHKAPGNKDFVYDSSAGQG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I + +D GI+ HP+ AG G + ND + N HGT AG A
Sbjct 152 ITIYGVDTGIDIRHPEFAGRIRWGTNTVDND----------NTDGNGHGTHTAGTFAGTT 201
Query 207 NNGVCGVGVAYNARIGGVRML 227
GVA A I V++L
Sbjct 202 ------YGVAKKANIVAVKVL 216
>sp|Q64K34|SUB3_ARTBE Subtilisin-like protease 3 OS=Arthroderma
benhamiae OX=63400 GN=SUB3 PE=1 SV=1
Length=397
Score = 34.3 bits (77), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 38/141 (27%), Positives = 55/141 (39%), Gaps = 22/141 (16%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ ++ +V ++E R K + T P P W L V+ + K G G
Sbjct 98 ILKDDKVNYVEHD---RVVK--LAALTTQPNAPT-WGLGRVSHKAPGNKDFVYDSSAGQG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I + +D GI+ HP+ AG G + ND + N HGT AG A
Sbjct 152 ITIYGVDTGIDIRHPEFAGRIRWGTNTVDND----------NTDGNGHGTHTAGTFAGTT 201
Query 207 NNGVCGVGVAYNARIGGVRML 227
GVA A I V++L
Sbjct 202 ------YGVAKKANIVAVKVL 216
>sp|D4AWY5|SUB3_ARTBC Subtilisin-like protease 3 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB3
PE=1 SV=1
Length=397
Score = 34.3 bits (77), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 38/141 (27%), Positives = 55/141 (39%), Gaps = 22/141 (16%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ ++ +V ++E R K + T P P W L V+ + K G G
Sbjct 98 ILKDDKVNYVEHD---RVVK--LAALTTQPNAPT-WGLGRVSHKAPGNKDFVYDSSAGQG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I + +D GI+ HP+ AG G + ND + N HGT AG A
Sbjct 152 ITIYGVDTGIDIRHPEFAGRIRWGTNTVDND----------NTDGNGHGTHTAGTFAGTT 201
Query 207 NNGVCGVGVAYNARIGGVRML 227
GVA A I V++L
Sbjct 202 ------YGVAKKANIVAVKVL 216
>sp|Q8J077|SUB6_TRISH Subtilisin-like protease 6 (Fragment) OS=Trichophyton
schoenleinii OX=34386 GN=SUB6 PE=1 SV=1
Length=405
Score = 34.3 bits (77), Expect = 5.0, Method: Compositional matrix adjust.
Identities = 29/107 (27%), Positives = 44/107 (41%), Gaps = 16/107 (15%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W L+ V + + G G+ ++D GI+ H D G G +F V+ +D D
Sbjct 134 WGLARVGSKQAGGTTYYYDSSAGKGVTAYVIDTGIDIEHEDFGGRAKWGKNF-VDQRDED 192
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD 228
N HGT AG V G G+A + + V++LD
Sbjct 193 C---------NGHGTHVAGTV------GGTKYGLAKSVSLVAVKVLD 224
>sp|P20015|PRTT_PARAQ Proteinase T (Fragment) OS=Parengyodontium
album OX=37998 GN=PROT PE=1 SV=1
Length=293
Score = 33.9 bits (76), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 27/85 (32%), Positives = 33/85 (39%), Gaps = 15/85 (18%)
Query 144 GHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVA 203
G G I+D GI NH D G +F + QD D N HGT AG V
Sbjct 42 GTGTCAYIIDTGIYTNHTDFGGRAKFLKNFAGDGQDTDG---------NGHGTHVAGTVG 92
Query 204 AVANNGVCGVGVAYNARIGGVRMLD 228
GVA + V++LD
Sbjct 93 GTT------YGVAKKTSLFAVKVLD 111
>sp|E4UWA4|SUB4_ARTGP Subtilisin-like protease 4 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB4
PE=3 SV=1
Length=399
Score = 33.9 bits (76), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 35/141 (25%), Positives = 52/141 (37%), Gaps = 22/141 (16%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ + +V ++EQ R T + W L V+ R + G G
Sbjct 100 ILNDSKVSYVEQDQVVR------ISGLTTQRSAPSWGLGRVSHRRAGSRDYVFDDSAGRG 153
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ + +D GI+ H D G A + N D D R+ HGT A A A
Sbjct 154 VTIYGVDTGIDIRHQDFGGR----ARWGTNTADRDNADRHG------HGTHTASTFAGTA 203
Query 207 NNGVCGVGVAYNARIGGVRML 227
G+A NA I V++L
Sbjct 204 ------FGIAKNANIVAVKVL 218
>sp|P40903|ISP6_SCHPO Sexual differentiation process putative
subtilase-type proteinase isp6 OS=Schizosaccharomyces pombe
(strain 972 / ATCC 24843) OX=284812 GN=isp6 PE=2 SV=1
Length=467
Score = 33.9 bits (76), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 26/84 (31%), Positives = 37/84 (44%), Gaps = 15/84 (18%)
Query 144 GHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVA 203
G I ++D G+ +H + G GA+ D D D +N HGT AG +A
Sbjct 212 GDNITAYVVDTGVSIHHVEFEGRASWGATIPSGDVDED---------NNGHGTHVAGTIA 262
Query 204 AVANNGVCGVGVAYNARIGGVRML 227
+ A GVA A I V++L
Sbjct 263 SRA------YGVAKKAEIVAVKVL 280
>sp|Q4V7M2|CRE2B_XENLA Cysteine-rich with EGF-like domain protein
2-B OS=Xenopus laevis OX=8355 GN=creld2-b PE=2 SV=1
Length=361
Score = 33.9 bits (76), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 5/46 (11%)
Query 618 FAPQVLDTHYSTE-NDVETIRASVCAPCHASCATCQGPALTDCLSC 662
F + D +YS+E ND +VC C+ +C TC GP+ DC C
Sbjct 174 FCLECSDGYYSSERNDTH----AVCIACNQACKTCNGPSNEDCKEC 215
>sp|Q2K7Z9|ANMK_RHIEC Anhydro-N-acetylmuramic acid kinase OS=Rhizobium
etli (strain CFN 42 / ATCC 51251) OX=347834 GN=anmK
PE=3 SV=1
Length=370
Score = 33.9 bits (76), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 17/52 (33%), Positives = 26/52 (50%), Gaps = 0/52 (0%)
Query 52 HGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKR 103
GF+ G G Y RG KR+L RP R +R +++ +EQ++ R
Sbjct 29 RGFIERGPFLGMPYDAEFRGRLKRALELARPLRDRNERPGELREIEQELTLR 80
>sp|Q69F57|SUB2_TRIRU Subtilisin-like protease 2 OS=Trichophyton
rubrum OX=5551 GN=SUB2 PE=3 SV=2
Length=421
Score = 33.9 bits (76), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 72/317 (23%), Positives = 112/317 (35%), Gaps = 105/317 (33%)
Query 120 QQWYLSG-VTQRDLNVKAAWAQGY----------------------TGHGIVVSILDDGI 156
Q +YL+ VTQR +A W GY G G+ +LD GI
Sbjct 117 QHFYLAKTVTQR----QARWGLGYMSSKGKPVPLHSTLVDYSYDDKAGEGVWAYVLDTGI 172
Query 157 EKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVA 216
NH + G G + P + ++ HGT AG +A GVA
Sbjct 173 NVNHVEFEGRAILGH---------NAIPNKSHTDEFGHGTCVAGIIAGKT------YGVA 217
Query 217 YNARIGGVRMLDG-----------------EVTDAVEARSLGLNPNHIHIYSASWGPEDD 259
A + + D +TD+ +N + I A + P DD
Sbjct 218 KKANVVSAKAFDTGSSTYNYILETYDWIIRNITDSNRKNKAVIN---LSISGAKYQPFDD 274
Query 260 GKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSIS- 318
AE AF G++ V A+GN G++ + N+I ++
Sbjct 275 A---------AERAFKAGITT---------VVAAGNDGKDAKNNTPASSPNAITVGAVRW 316
Query 319 -----SATQFGNVP--WYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASA 371
S + +G + W A + + + GN T + +GTSA++
Sbjct 317 ENTRPSFSNYGKIVDIW---APGELIKSCWKGGNN-------------ATSTQSGTSAAS 360
Query 372 PLAAGIIALTLEANKNL 388
P AG++A L + KNL
Sbjct 361 PHVAGLVAY-LMSIKNL 376
>sp|C5NZT2|SUB4B_COCP7 Subtilisin-like protease CPC735_012930
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_012930
PE=3 SV=1
Length=377
Score = 33.9 bits (76), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 16/107 (15%)
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
W L ++ K G G++ ++D GI+ NHP+ G + G + V++ D
Sbjct 128 SWGLGRISHTFRGFKNYLYHSSAGEGVLAYVVDTGIDINHPEFEGRAEWGINV-VDEVDT 186
Query 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
D ++ HGT AG + G GVA ++ V+ L
Sbjct 187 D---------EHGHGTHVAGTI------GSKTFGVAKKVKLVAVKAL 218
>sp|Q7T364|TPL2B_DANRE Tumor necrosis factor, alpha-induced protein
8-like protein 2 B OS=Danio rerio OX=7955 GN=tnfaip8l2b
PE=2 SV=1
Length=186
Score = 33.1 bits (74), Expect = 7.1, Method: Composition-based stats.
Identities = 24/77 (31%), Positives = 33/77 (43%), Gaps = 0/77 (0%)
Query 429 LDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQ 488
L GAM A++ + + + DILTE +D+ +L T G NH+
Sbjct 94 LRQGAMTAISFHEVDFTFDKTVMSDILTESRDMLLKLVNTHLTTKSHGRINHVFNHYADP 153
Query 489 ARLTLSYNRRGDLAIHL 505
LT YN G L HL
Sbjct 154 ELLTQLYNSSGPLKPHL 170
>sp|Q5XH36|CRE2A_XENLA Cysteine-rich with EGF-like domain protein
2-A OS=Xenopus laevis OX=8355 GN=creld2-a PE=2 SV=1
Length=361
Score = 33.5 bits (75), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 5/48 (10%)
Query 618 FAPQVLDTHYSTE-NDVETIRASVCAPCHASCATCQGPALTDCLSCPS 664
F + D ++S+E ND S+C C+ +C TC GP+ DC C +
Sbjct 174 FCLECADEYFSSERNDT----YSLCTACNQACKTCDGPSNEDCKECKN 217
>sp|Q8J0D7|SUB3_ARTOT Subtilisin-like protease 3 OS=Arthroderma
otae OX=63405 GN=SUB3 PE=1 SV=1
Length=397
Score = 33.5 bits (75), Expect = 8.6, Method: Compositional matrix adjust.
Identities = 33/114 (29%), Positives = 44/114 (39%), Gaps = 17/114 (15%)
Query 114 TDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
T P P W L V+ + K G G+ + +D GI+ NHP+ G G +
Sbjct 120 TQPNAPT-WGLGRVSHKAPGNKDFVYDSSAGQGVTIYGVDTGIDINHPEFRGRIRWGTNT 178
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
ND + N HGT AG A GVA A I V++L
Sbjct 179 VDND----------NTDGNGHGTHTAGTFAGTT------YGVAKKANIVAVKVL 216
>sp|C5FMY5|SUB3_ARTOC Subtilisin-like protease 3 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB3
PE=3 SV=1
Length=397
Score = 33.5 bits (75), Expect = 8.6, Method: Compositional matrix adjust.
Identities = 33/114 (29%), Positives = 44/114 (39%), Gaps = 17/114 (15%)
Query 114 TDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
T P P W L V+ + K G G+ + +D GI+ NHP+ G G +
Sbjct 120 TQPNAPT-WGLGRVSHKAPGNKDFVYDSSAGQGVTIYGVDTGIDINHPEFRGRIRWGTNT 178
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
ND + N HGT AG A GVA A I V++L
Sbjct 179 VDND----------NTDGNGHGTHTAGTFAGTT------YGVAKKANIVAVKVL 216
>sp|P0CY46|EGFR_APIME Epidermal growth factor receptor OS=Apis
mellifera OX=7460 GN=Egfr PE=2 SV=1
Length=1292
Score = 33.5 bits (75), Expect = 9.4, Method: Compositional matrix adjust.
Identities = 41/165 (25%), Positives = 61/165 (37%), Gaps = 18/165 (11%)
Query 581 PPESSGCKTLTSSQACVVCEE------GFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
P E K L S C C G+ H+ C + Q D D
Sbjct 502 PLEQGPLKPLASKAVCRKCHSRCKKCTGYGFHEHVCQECTKYKRGEQCED---ECPADYF 558
Query 635 TIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRL 694
+C PC + C C GP C C ++ + + S + E+ + P ++
Sbjct 559 ADANKLCIPCFSECRGCFGPGPNQCYKCRNYKIYIDEDTDGNTTSFNCTETCTPEYPHKI 618
Query 695 -PPEVEAGQRLR-AGLLPSHL-PEVVAGLSCAFIVLVFVTVFLVL 736
P+ E L AGL+ + L P ++AG V VF FLV+
Sbjct 619 FNPDSEPYCSLETAGLIENELQPAILAG------VAVFALAFLVV 657
Lambda K H a alpha
0.317 0.132 0.414 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 89977505152
Results from round 2
Query= sp|P09958|FURIN_HUMAN Furin OS=Homo sapiens OX=9606 GN=FURIN PE=1
SV=2
Length=794
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|P23188|FURIN_MOUSE Furin OS=Mus musculus OX=10090 GN=Furin PE=... 1212 0.0
sp|P09958|FURIN_HUMAN Furin OS=Homo sapiens OX=9606 GN=FURIN PE=1... 1201 0.0
sp|P23377|FURIN_RAT Furin OS=Rattus norvegicus OX=10116 GN=Furin ... 1200 0.0
sp|Q28193|FURIN_BOVIN Furin OS=Bos taurus OX=9913 GN=FURIN PE=1 SV=1 1196 0.0
sp|P29119|FURI1_XENLA Furin-1 OS=Xenopus laevis OX=8355 GN=furin ... 1092 0.0
sp|P63239|NEC1_MOUSE Neuroendocrine convertase 1 OS=Mus musculus ... 857 0.0
sp|P63240|NEC1_MUSCO Neuroendocrine convertase 1 OS=Mus cookii OX... 857 0.0
sp|P28840|NEC1_RAT Neuroendocrine convertase 1 OS=Rattus norvegic... 851 0.0
sp|Q6UW60|PCSK4_HUMAN Proprotein convertase subtilisin/kexin type... 847 0.0
sp|Q63415|PCSK6_RAT Proprotein convertase subtilisin/kexin type 6... 846 0.0
sp|P29122|PCSK6_HUMAN Proprotein convertase subtilisin/kexin type... 840 0.0
sp|Q04592|PCSK5_MOUSE Proprotein convertase subtilisin/kexin type... 827 0.0
sp|P41413|PCSK5_RAT Proprotein convertase subtilisin/kexin type 5... 823 0.0
sp|P29120|NEC1_HUMAN Neuroendocrine convertase 1 OS=Homo sapiens ... 822 0.0
sp|Q92824|PCSK5_HUMAN Proprotein convertase subtilisin/kexin type... 816 0.0
sp|Q9GLR1|NEC1_BOVIN Neuroendocrine convertase 1 OS=Bos taurus OX... 804 0.0
sp|Q78EH2|PCSK4_RAT Proprotein convertase subtilisin/kexin type 4... 775 0.0
sp|Q9NJ15|PCSK5_BRACL Proprotein convertase subtilisin/kexin type... 765 0.0
sp|P26016|FUR11_DROME Furin-like protease 1, isoforms 1/1-X/2 OS=... 756 0.0
sp|P29121|PCSK4_MOUSE Proprotein convertase subtilisin/kexin type... 748 0.0
sp|P30430|FUR1C_DROME Furin-like protease 1, isoform 1-CRR OS=Dro... 738 0.0
sp|O17798|FKPC1_CAEEL Furin-like protease kpc-1 OS=Caenorhabditis... 711 0.0
sp|Q5REC2|NEC2_PONAB Neuroendocrine convertase 2 OS=Pongo abelii ... 703 0.0
sp|P21661|NEC2_MOUSE Neuroendocrine convertase 2 OS=Mus musculus ... 701 0.0
sp|P16519|NEC2_HUMAN Neuroendocrine convertase 2 OS=Homo sapiens ... 701 0.0
sp|P28841|NEC2_RAT Neuroendocrine convertase 2 OS=Rattus norvegic... 700 0.0
sp|Q03333|NEC2_PIG Neuroendocrine convertase 2 OS=Sus scrofa OX=9... 694 0.0
sp|P30432|FUR2_DROME Furin-like protease 2 OS=Drosophila melanoga... 690 0.0
sp|Q9GLR0|NEC2_BOVIN Neuroendocrine convertase 2 OS=Bos taurus OX... 685 0.0
sp|P29146|NECA_HYDVU PC3-like endoprotease variant A OS=Hydra vul... 673 0.0
sp|G5ECN9|NEC2_CAEEL Neuroendocrine convertase 2 OS=Caenorhabditi... 671 0.0
sp|Q62849|PCSK7_RAT Proprotein convertase subtilisin/kexin type 7... 669 0.0
sp|P29145|NECB_HYDVU PC3-like endoprotease variant B OS=Hydra vul... 668 0.0
sp|P51559|BLI4_CAEEL Endoprotease bli-4 OS=Caenorhabditis elegans... 663 0.0
sp|Q61139|PCSK7_MOUSE Proprotein convertase subtilisin/kexin type... 662 0.0
sp|Q9VBC7|NEC2_DROME Neuroendocrine convertase 2 OS=Drosophila me... 661 0.0
sp|Q16549|PCSK7_HUMAN Proprotein convertase subtilisin/kexin type... 648 0.0
sp|A0A044RE18|BLI_ONCVO Endoprotease bli OS=Onchocerca volvulus O... 639 0.0
sp|P09231|KEX1A_KLULA Protease KEX1 OS=Kluyveromyces lactis (stra... 562 0.0
sp|Q09175|KRP1_SCHPO Dibasic-processing endoprotease OS=Schizosac... 560 0.0
sp|P13134|KEX2_YEAST Kexin OS=Saccharomyces cerevisiae (strain AT... 543 0.0
sp|O13359|KEX2_CANAW Kexin OS=Candida albicans (strain WO-1) OX=2... 521 3e-171
sp|P42781|XPR6_YARLI Dibasic-processing endoprotease OS=Yarrowia ... 522 4e-171
sp|P91863|AEX5_CAEEL Endoprotease aex-5 OS=Caenorhabditis elegans... 417 3e-136
sp|P23916|PRCA_TRIV2 Calcium-dependent protease OS=Trichormus var... 349 1e-108
sp|Q59149|PRCA_NOSS1 Calcium-dependent protease OS=Nostoc sp. (st... 347 6e-108
sp|Q9L5A4|ASP_AERSO Aeromonas extracellular serine protease OS=Ae... 319 9e-98
sp|P42780|BPRX_DICNO Extracellular subtilisin-like protease OS=Di... 315 3e-96
sp|P42779|BPRV_DICNO Extracellular basic protease OS=Dichelobacte... 291 2e-87
sp|P31339|ASPA_AERSA Microbial serine proteinase OS=Aeromonas sal... 277 6e-82
sp|P16396|SUBE_BACSU Minor extracellular protease Epr OS=Bacillus... 234 9e-66
sp|Q99405|PRTM_SHOC1 M-protease OS=Shouchella clausii (strain KSM... 222 3e-64
sp|Q00139|VG47_ICHVA Subtilisin-like protease OS=Ictalurid herpes... 221 1e-63
sp|P27693|ELYA_ALKAL Alkaline protease OS=Alkalihalobacillus alca... 220 3e-63
sp|P41362|ELYA_SHOCL Alkaline protease OS=Shouchella clausii OX=7... 218 1e-62
sp|P58502|TKSU_THEKO Tk-subtilisin OS=Thermococcus kodakarensis (... 217 7e-62
sp|Q93LQ6|FLS_FERPE Fervidolysin OS=Fervidobacterium pennivorans ... 223 2e-61
sp|P04189|SUBT_BACSU Subtilisin E OS=Bacillus subtilis (strain 16... 211 3e-60
sp|P35835|SUBN_BACNA Subtilisin NAT OS=Bacillus subtilis subsp. n... 211 4e-60
sp|P20724|ELYA_BACYA Alkaline elastase YaB OS=Bacillus sp. (strai... 209 2e-59
sp|P29599|SUBB_LEDLE Subtilisin BL OS=Lederbergia lenta OX=1467 P... 206 2e-59
sp|P29143|HLY_NATA1 Halolysin OS=Natrialba asiatica (strain ATCC ... 213 3e-59
sp|P29142|SUBT_GEOSE Subtilisin J OS=Geobacillus stearothermophil... 206 2e-58
sp|P00783|SUBT_BACSA Subtilisin amylosacchariticus OS=Bacillus su... 206 3e-58
sp|P23314|EXPR_XANCP Extracellular protease OS=Xanthomonas campes... 210 9e-58
sp|P29600|SUBS_LEDLE Subtilisin Savinase OS=Lederbergia lenta OX=... 198 9e-57
sp|I3R794|HLY_HALMT Halolysin OS=Haloferax mediterranei (strain A... 205 3e-56
sp|P16588|PROA_VIBAL Alkaline serine exoprotease A OS=Vibrio algi... 203 1e-55
sp|P00780|SUBC_BACLI Subtilisin Carlsberg OS=Bacillus licheniform... 196 2e-54
sp|Q45670|THES_BACSJ Thermophilic serine proteinase OS=Bacillus s... 195 4e-54
sp|P00782|SUBT_BACAM Subtilisin BPN' OS=Bacillus amyloliquefacien... 194 8e-54
sp|P07518|SUBT_BACPU Subtilisin OS=Bacillus pumilus OX=1408 GN=ap... 190 8e-54
sp|P58371|SPM1_PYRO7 Subtilisin-like proteinase Spm1 OS=Pyricular... 195 1e-52
sp|Q9RYM8|SUB2_DEIRA Probable subtilase-type serine protease DR_A... 198 2e-52
sp|P11018|ISP1_BACSU Major intracellular serine protease OS=Bacil... 188 2e-52
sp|W7K9M0|SUB1_PLAFO Subtilisin-like protease 1 OS=Plasmodium fal... 196 4e-52
sp|Q8I0V0|SUB1_PLAF7 Subtilisin-like protease 1 OS=Plasmodium fal... 196 4e-52
sp|O61142|SUB1_PLAFA Subtilisin-like protease 1 OS=Plasmodium fal... 196 5e-52
sp|P41363|ELYA_HALH5 Thermostable alkaline protease OS=Halalkalib... 188 1e-51
sp|P29139|ISP_PAEPO Intracellular serine protease OS=Paenibacillu... 184 9e-51
sp|Q8IHZ5|SUB2_PLAF7 Subtilisin-like protease 2 OS=Plasmodium fal... 196 2e-50
sp|O97364|SUB2_PLAFA Subtilisin-like protease 2 OS=Plasmodium fal... 195 3e-50
sp|O31788|APRX_BACSU Serine protease AprX OS=Bacillus subtilis (s... 185 4e-50
sp|P04072|THET_THEVU Thermitase OS=Thermoactinomyces vulgaris OX=... 180 9e-50
sp|P29138|CUDP_METAN Cuticle-degrading protease OS=Metarhizium an... 177 1e-47
sp|Q9Y008|SUB2_PLAFP Subtilisin-like protease 2 OS=Plasmodium fal... 183 2e-46
sp|L8G6I7|SUB1_PSED2 Subtilisin-like protease 1 OS=Pseudogymnoasc... 172 1e-45
sp|Q68GV9|ALP_LECPS Alkaline serine protease ver112 OS=Lecanicill... 169 9e-45
sp|P25036|YSP3_YEAST Subtilisin-like protease 3 OS=Saccharomyces ... 162 1e-41
sp|P29141|SUBV_BACSU Minor extracellular protease Vpr OS=Bacillus... 143 6e-34
sp|P09489|PRTS_SERMA Extracellular serine protease OS=Serratia ma... 137 5e-32
sp|P29805|PRTT_SERMA Extracellular serine protease OS=Serratia ma... 132 2e-30
sp|P81719|PIIS_ACHLY Protease 2 small chain (Fragment) OS=Achromo... 69.8 1e-13
sp|Q80T14|FRAS1_MOUSE Extracellular matrix organizing protein FRA... 75.2 2e-12
Sequences not found previously or not previously below threshold:
sp|P00781|SUBD_BACLI Subtilisin DY OS=Bacillus licheniformis OX=1... 184 1e-51
sp|P80146|SEPR_THESR Extracellular serine proteinase OS=Thermus s... 175 1e-46
sp|L8FSM5|SUB2_PSED2 Subtilisin-like protease 2 OS=Pseudogymnoasc... 173 5e-46
sp|Q5RLZ1|NEP_NATMA Halolysin-like extracellular serine protease ... 176 6e-46
sp|D4DKQ4|SUB8_TRIVH Subtilisin-like protease 8 OS=Trichophyton v... 173 3e-45
sp|D4AX50|SUB8_ARTBC Subtilisin-like protease 8 OS=Arthroderma be... 171 9e-45
sp|Q9P8G3|PEN18_PENRB Subtilisin-like serine protease Pen ch 18.0... 171 1e-44
sp|P9WEW5|PCH18_PENRB Subtilisin-like serine protease Pen ch 18 O... 170 2e-44
sp|P9WEW6|PCH18_PENCH Subtilisin-like serine protease EN45_078720... 170 2e-44
sp|P29140|ISP_SHOCL Intracellular alkaline protease OS=Shouchella... 165 4e-44
sp|C5FII2|SUB8_ARTOC Subtilisin-like protease 8 OS=Arthroderma ot... 169 4e-44
sp|C5P4Z8|SUB8_COCP7 Subtilisin-like protease CPC735_031240 OS=Co... 169 5e-44
sp|P33295|PEPC_ASPNG Subtilisin-like serine protease pepC OS=Aspe... 167 5e-43
sp|P54423|WPRA_BACSU Cell wall-associated protease OS=Bacillus su... 171 6e-43
sp|B7ZK61|CH901_DAVTA Subtilisin-like serine protease Cla h 9.010... 165 2e-42
sp|B3V0K8|CL401_COCLU Subtilisin-like serine protease Cur l 4.010... 164 3e-42
sp|C5PCB1|SUB4A_COCP7 Subtilisin-like protease CPC735_066880 OS=C... 160 1e-41
sp|Q9Y755|PENC2_PENCI Subtilisin-like serine protease Pen c 2 OS=... 161 1e-41
sp|P06873|PRTK_PARAQ Proteinase K OS=Parengyodontium album OX=379... 160 1e-41
sp|Q3ZEJ8|SUB6_TRITO Subtilisin-like protease 6 OS=Trichophyton t... 160 2e-41
sp|A1XIH0|SUB6_TRIEQ Subtilisin-like protease 6 OS=Trichophyton e... 160 2e-41
sp|P87184|ALP2_ASPFU Alkaline protease 2 OS=Aspergillus fumigatus... 161 3e-41
sp|B0Y473|ALP2_ASPFC Alkaline protease 2 OS=Aspergillus fumigatus... 161 3e-41
sp|E4V2V9|SUB7_ARTGP Subtilisin-like protease 7 OS=Arthroderma gy... 159 3e-41
sp|P09232|PRTB_YEAST Cerevisin OS=Saccharomyces cerevisiae (strai... 163 5e-41
sp|P23653|PRTR_PARAQ Proteinase R OS=Parengyodontium album OX=379... 157 1e-40
sp|E4V4J8|SUB6_ARTGP Subtilisin-like protease 6 OS=Arthroderma gy... 156 4e-40
sp|Q8J077|SUB6_TRISH Subtilisin-like protease 6 (Fragment) OS=Tri... 156 5e-40
sp|P40903|ISP6_SCHPO Sexual differentiation process putative subt... 156 9e-40
sp|E4UN97|SUB3_ARTGP Subtilisin-like protease 3 OS=Arthroderma gy... 154 1e-39
sp|L8GD75|SUB3_PSED2 Subtilisin-like protease 3 OS=Pseudogymnoasc... 154 2e-39
sp|Q8J0D7|SUB3_ARTOT Subtilisin-like protease 3 OS=Arthroderma ot... 154 2e-39
sp|C5FMY5|SUB3_ARTOC Subtilisin-like protease 3 OS=Arthroderma ot... 154 2e-39
sp|P16397|SUBF_BACSU Bacillopeptidase F OS=Bacillus subtilis (str... 161 2e-39
sp|A1XIH1|SUB6_TRISD Subtilisin-like protease 6 OS=Trichophyton s... 153 3e-39
sp|Q9UW97|SUB6_TRIRU Subtilisin-like protease 6 OS=Trichophyton r... 153 3e-39
sp|Q32ZM1|RM201_RHOMI Subtilisin-like serine protease Rho m 2.010... 151 4e-39
sp|B8XGQ6|SUB3_TRITO Subtilisin-like protease 3 OS=Trichophyton t... 153 5e-39
sp|C5FH27|SUB9_ARTOC Subtilisin-like protease 9 OS=Arthroderma ot... 152 9e-39
sp|P08594|AQL1_THEAQ Aqualysin-1 OS=Thermus aquaticus OX=271 GN=p... 154 9e-39
sp|Q9UTS0|PSP3_SCHPO Subtilase-type proteinase psp3 OS=Schizosacc... 153 9e-39
sp|C5FJA5|SUB7_ARTOC Subtilisin-like protease 7 OS=Arthroderma ot... 151 1e-38
sp|Q64K31|SUB6_ARTBE Subtilisin-like protease 6 OS=Arthroderma be... 152 1e-38
sp|D4ALV9|SUB6_ARTBC Subtilisin-like protease 6 OS=Arthroderma be... 152 1e-38
sp|D4D5H3|SUB6_TRIVH Subtilisin-like protease 6 OS=Trichophyton v... 151 2e-38
sp|Q5VJ72|SUB6_TRIVC Subtilisin-like protease 6 OS=Trichophyton v... 151 2e-38
sp|B6VA86|SUB3_TRIEQ Subtilisin-like protease 3 OS=Trichophyton e... 150 3e-38
sp|C5PFR5|SU11B_COCP7 Subtilisin-like protease CPC735_047380 OS=C... 150 5e-38
sp|G1X8P8|SPAZ_ARTOA Cuticle-degrading serine protease OS=Arthrob... 150 5e-38
sp|D4CZQ4|SUB7_TRIVH Subtilisin-like protease 7 OS=Trichophyton v... 150 6e-38
sp|Q5JIZ5|TKSP_THEKO Subtilisin-like serine protease OS=Thermococ... 154 8e-38
sp|D4APA9|SUB7_ARTBC Subtilisin-like protease 7 OS=Arthroderma be... 149 1e-37
sp|C5P1W9|SU11A_COCP7 Subtilisin-like protease CPC735_035780 OS=C... 149 1e-37
sp|Q5VJ71|SUB7_TRIVC Subtilisin-like protease 7 OS=Trichophyton v... 149 1e-37
sp|C5PCX1|SUB7B_COCP7 Subtilisin-like protease CPC735_015300 OS=C... 148 2e-37
sp|Q64K36|SUB7_ARTBE Subtilisin-like protease 7 OS=Arthroderma be... 148 2e-37
sp|Q8NID9|SUB7_TRIRU Subtilisin-like protease 7 OS=Trichophyton r... 147 4e-37
sp|A1XIH6|SUB7_TRIVO Subtilisin-like protease 7 OS=Trichophyton v... 147 6e-37
sp|G3FNQ9|SPAZ_ORBOL Cuticle-degrading serine protease OS=Orbilia... 147 6e-37
sp|Q9Y749|PENC1_PENCI Subtilisin-like serine protease Pen c 1 OS=... 145 1e-36
sp|D4DLA2|SUB3_TRIVH Subtilisin-like protease 3 OS=Trichophyton v... 145 3e-36
sp|Q5VJ75|SUB3_TRIVC Subtilisin-like protease 3 OS=Trichophyton v... 145 3e-36
sp|Q64K34|SUB3_ARTBE Subtilisin-like protease 3 OS=Arthroderma be... 145 3e-36
sp|D4AWY5|SUB3_ARTBC Subtilisin-like protease 3 OS=Arthroderma be... 145 3e-36
sp|A1XIH5|SUB7_TRISD Subtilisin-like protease 7 OS=Trichophyton s... 144 3e-36
sp|A1XIH3|SUB7_TRIEQ Subtilisin-like protease 7 OS=Trichophyton e... 144 6e-36
sp|A1XIH4|SUB7_TRITO Subtilisin-like protease 7 OS=Trichophyton t... 143 8e-36
sp|Q9URR2|PEN13_PENRB Subtilisin-like serine protease Pen ch 13.0... 143 1e-35
sp|C5FQI3|SUB6_ARTOC Subtilisin-like protease 6 OS=Arthroderma ot... 143 2e-35
sp|D4B5N1|SUB9_ARTBC Subtilisin-like protease 9 OS=Arthroderma be... 141 3e-35
sp|C5P6D1|SUB2A_COCP7 Subtilisin-like protease CPC735_023170 OS=C... 141 4e-35
sp|R4IR27|ASES_SARSR Subtilisin-like serine protease AsES OS=Saro... 141 5e-35
sp|Q69F56|SUB3_TRIRU Subtilisin-like protease 3 OS=Trichophyton r... 141 5e-35
sp|E4UTU7|SUB9_ARTGP Subtilisin-like protease 9 OS=Arthroderma gy... 139 1e-34
sp|D4D6Q4|SUB4_TRIVH Subtilisin-like protease 4 OS=Trichophyton v... 139 2e-34
sp|Q5VJ74|SUB4_TRIVC Subtilisin-like protease 4 OS=Trichophyton v... 139 2e-34
sp|Q64K33|SUB4_ARTBE Subtilisin-like protease 4 OS=Arthroderma be... 139 2e-34
sp|D4AXW3|SUB4_ARTBC Subtilisin-like protease 4 OS=Arthroderma be... 139 2e-34
sp|Q69F35|SUB4_TRIRU Subtilisin-like protease 4 OS=Trichophyton r... 139 2e-34
sp|C5PGK9|SUB7A_COCP7 Subtilisin-like protease CPC735_050320 OS=C... 139 2e-34
sp|D4D674|SUB9_TRIVH Subtilisin-like protease 9 OS=Trichophyton v... 139 2e-34
sp|A7UKV6|SUB4_TRIEQ Subtilisin-like protease 4 (Fragment) OS=Tri... 139 3e-34
sp|B8XGQ7|SUB4_TRITO Subtilisin-like protease 4 OS=Trichophyton t... 139 3e-34
sp|C5FXZ6|SUB4_ARTOC Subtilisin-like protease 4 OS=Arthroderma ot... 138 4e-34
sp|P28842|SUBT_BACS9 Subtilisin OS=Bacillus sp. (strain TA39) OX=... 139 4e-34
sp|C5P5Q3|SUB9_COCP7 Subtilisin-like protease CPC735_033790 OS=Co... 138 5e-34
sp|P20015|PRTT_PARAQ Proteinase T (Fragment) OS=Parengyodontium a... 135 7e-34
sp|Q8SQJ3|SPL1_ENCCU Putative subtilisin-like proteinase 1 OS=Enc... 139 9e-34
sp|P29118|ALP_HAPCH Alkaline proteinase OS=Hapsidospora chrysogen... 137 1e-33
sp|C5P9H3|SUB7D_COCP7 Subtilisin-like protease CPC735_005570 OS=C... 137 1e-33
sp|Q5VJ77|SUB1_TRIVC Subtilisin-like protease 1 (Fragment) OS=Tri... 135 5e-33
sp|Q64K30|SUB1_ARTBE Subtilisin-like protease 1 (Fragment) OS=Art... 135 5e-33
sp|E4UPZ4|SUB1_ARTGP Subtilisin-like protease 1 OS=Arthroderma gy... 136 7e-33
sp|Q69F58|SUB1_TRIRU Subtilisin-like protease 1 OS=Trichophyton r... 136 9e-33
sp|E4UWA4|SUB4_ARTGP Subtilisin-like protease 4 OS=Arthroderma gy... 133 2e-32
sp|D4AKU9|SUB1_ARTBC Subtilisin-like protease 1 OS=Arthroderma be... 134 8e-32
sp|B6VA84|SUB1_TRIEQ Subtilisin-like protease 1 OS=Trichophyton e... 133 9e-32
sp|D4DIW9|SUB1_TRIVH Subtilisin-like protease 1 OS=Trichophyton v... 134 1e-31
sp|P12547|ORYZ_ASPOR Alkaline protease 1 OS=Aspergillus oryzae (s... 131 1e-31
sp|B8N106|ORYZ_ASPFN Alkaline protease 1 OS=Aspergillus flavus (s... 131 1e-31
sp|B8XGQ4|SUB1_TRITO Subtilisin-like protease 1 OS=Trichophyton t... 133 1e-31
sp|P9WEW3|PCH13_PENRB Subtilisin-like serine protease Pen ch 13 O... 131 2e-31
sp|P9WEW4|PCH13_PENCH Subtilisin-like serine protease EN45_076310... 131 2e-31
sp|C5G1D1|SUB5_ARTOC Subtilisin-like protease 5 OS=Arthroderma ot... 129 7e-31
sp|A1CIA7|ORYZ_ASPCL Alkaline protease 1 OS=Aspergillus clavatus ... 128 1e-30
sp|D4DIS6|SUB10_TRIVH Subtilisin-like protease 10 OS=Trichophyton... 130 2e-30
sp|A1CWF3|ORYZ_NEOFI Alkaline protease 1 OS=Neosartorya fischeri ... 127 2e-30
sp|C5NZT2|SUB4B_COCP7 Subtilisin-like protease CPC735_012930 OS=C... 125 9e-30
sp|P28296|ORYZ_ASPFU Alkaline protease 1 OS=Aspergillus fumigatus... 124 2e-29
sp|B0Y708|ORYZ_ASPFC Alkaline protease 1 OS=Aspergillus fumigatus... 124 2e-29
sp|C5P6L5|SUB4C_COCP7 Subtilisin-like protease CPC735_024010 OS=C... 124 3e-29
sp|Q03420|ALP_HYPAT Alkaline proteinase OS=Hypocrea atroviridis O... 124 3e-29
sp|D4D1U5|SUB12_TRIVH Subtilisin-like protease 12 OS=Trichophyton... 124 3e-29
sp|E4UZP9|SUB2_ARTGP Subtilisin-like protease 2 OS=Arthroderma gy... 124 4e-29
sp|D4AQA9|SUB12_ARTBC Subtilisin-like protease 12 OS=Arthroderma ... 124 4e-29
sp|Q64K35|SUB2_ARTBE Subtilisin-like protease 2 OS=Arthroderma be... 124 4e-29
sp|D4AZ75|SUB2_ARTBC Subtilisin-like protease 2 OS=Arthroderma be... 124 5e-29
sp|C5NZ69|SUB7C_COCP7 Subtilisin-like protease CPC735_013700 OS=C... 123 5e-29
sp|Q5VJ76|SUB2_TRIVC Subtilisin-like protease 2 OS=Trichophyton v... 123 6e-29
sp|D4DLI5|SUB2_TRIVH Subtilisin-like protease 2 OS=Trichophyton v... 123 7e-29
sp|B6VA85|SUB2_TRIEQ Subtilisin-like protease 2 OS=Trichophyton e... 123 8e-29
sp|Q69F57|SUB2_TRIRU Subtilisin-like protease 2 OS=Trichophyton r... 123 8e-29
sp|B8XGQ5|SUB2_TRITO Subtilisin-like protease 2 OS=Trichophyton t... 123 9e-29
sp|Q00208|ORYZ_EMENI Alkaline protease 1 OS=Emericella nidulans (... 123 1e-28
sp|C5NZ70|SUB2C_COCP7 Subtilisin-like protease CPC735_013710 OS=C... 122 1e-28
sp|Q9Y778|SMP1_MAGPO Subtilisin-like proteinase Mp1 OS=Magnaporth... 122 1e-28
sp|Q8J0D9|SUB1_ARTOT Subtilisin-like protease 1 OS=Arthroderma ot... 124 1e-28
sp|C5FPS1|SUB1_ARTOC Subtilisin-like protease 1 OS=Arthroderma ot... 124 1e-28
sp|C5G168|SUB2_ARTOC Subtilisin-like protease 2 OS=Arthroderma ot... 121 3e-28
sp|P25381|RRT12_YEAST Subtilase-type proteinase RRT12 OS=Saccharo... 123 3e-28
sp|P09230|AEP_YARLI Alkaline extracellular protease OS=Yarrowia l... 122 3e-28
sp|D4AQG0|SUB10_ARTBC Subtilisin-like protease 10 OS=Arthroderma ... 122 7e-28
sp|P35211|ORYZ_ASPFL Alkaline protease 1 OS=Aspergillus flavus OX... 119 1e-27
sp|D4B194|SUB5_ARTBC Subtilisin-like protease 5 OS=Arthroderma be... 119 1e-27
sp|E4UY04|SUB12_ARTGP Subtilisin-like protease 12 OS=Arthroderma ... 118 2e-27
sp|Q1DFT5|POPC_MYXXD Subtilisin-like protease PopC OS=Myxococcus ... 119 4e-27
sp|Q8J0D8|SUB2_ARTOT Subtilisin-like protease 2 OS=Arthroderma ot... 117 7e-27
sp|C5P906|SUB2B_COCP7 Subtilisin-like protease CPC735_003880 OS=C... 116 1e-26
sp|E4V2L6|SUB5_ARTGP Subtilisin-like protease 5 OS=Arthroderma gy... 115 3e-26
sp|C5FZ39|SUB11_ARTOC Subtilisin-like protease 11 OS=Arthroderma ... 114 4e-26
sp|C5FX37|SUB10_ARTOC Subtilisin-like protease 10 OS=Arthroderma ... 109 2e-24
sp|D4CZ60|SUB11_TRIVH Subtilisin-like protease 11 OS=Trichophyton... 109 3e-24
sp|D4APE3|SUB11_ARTBC Subtilisin-like protease 11 OS=Arthroderma ... 109 4e-24
sp|P72186|PLS_PYRFU Pyrolysin OS=Pyrococcus furiosus (strain ATCC... 112 4e-24
sp|Q0WUG6|SBT61_ARATH Subtilisin-like protease SBT6.1 OS=Arabidop... 112 5e-24
sp|E4V5C5|SUB11_ARTGP Subtilisin-like protease 11 OS=Arthroderma ... 108 8e-24
sp|Q14703|MBTP1_HUMAN Membrane-bound transcription factor site-1 ... 109 3e-23
sp|Q9Z2A8|MBTP1_CRIGR Membrane-bound transcription factor site-1 ... 108 7e-23
sp|Q9WTZ3|MBTP1_RAT Membrane-bound transcription factor site-1 pr... 108 7e-23
sp|P59996|PCSK9_RAT Proprotein convertase subtilisin/kexin type 9... 107 1e-22
sp|Q9WTZ2|MBTP1_MOUSE Membrane-bound transcription factor site-1 ... 107 2e-22
sp|Q80W65|PCSK9_MOUSE Proprotein convertase subtilisin/kexin type... 106 2e-22
sp|Q07596|NISP_LACLL Nisin leader peptide-processing serine prote... 104 6e-22
sp|P30199|EPIP_STAEP Epidermin leader peptide-processing serine p... 103 7e-22
sp|O53695|MYCP3_MYCTU Mycosin-3 OS=Mycobacterium tuberculosis (st... 101 4e-21
sp|Q69F34|SUB5_TRIRU Subtilisin-like protease 5 OS=Trichophyton r... 99.1 8e-21
sp|A8T6A6|PCSK9_LAGLA Proprotein convertase subtilisin/kexin type... 101 8e-21
sp|A8T6A1|PCSK9_ATEGE Proprotein convertase subtilisin/kexin type... 101 9e-21
sp|B8XGQ8|SUB5_TRITO Subtilisin-like protease 5 OS=Trichophyton t... 99.1 9e-21
sp|B6VA87|SUB5_TRIEQ Subtilisin-like protease 5 OS=Trichophyton e... 99.1 9e-21
sp|D4D0F5|SUB5_TRIVH Subtilisin-like protease 5 OS=Trichophyton v... 98.7 1e-20
sp|Q5VJ73|SUB5_TRIVC Subtilisin-like protease 5 OS=Trichophyton v... 98.7 1e-20
sp|Q64K32|SUB5_ARTBE Subtilisin-like protease 5 OS=Arthroderma be... 98.7 1e-20
sp|A8T677|PCSK9_PLEMO Proprotein convertase subtilisin/kexin type... 100 2e-20
sp|A8T688|PCSK9_CALJA Proprotein convertase subtilisin/kexin type... 99.5 4e-20
sp|A8T644|PCSK9_PANTR Proprotein convertase subtilisin/kexin type... 98.3 7e-20
sp|A8T650|PCSK9_GORGO Proprotein convertase subtilisin/kexin type... 98.3 8e-20
sp|Q8NBP7|PCSK9_HUMAN Proprotein convertase subtilisin/kexin type... 98.0 1e-19
sp|A8T695|PCSK9_SAIBB Proprotein convertase subtilisin/kexin type... 98.0 1e-19
sp|A8T672|PCSK9_COLGU Proprotein convertase subtilisin/kexin type... 97.6 1e-19
sp|A8T666|PCSK9_MACMU Proprotein convertase subtilisin/kexin type... 97.2 2e-19
sp|A8T662|PCSK9_MACNE Proprotein convertase subtilisin/kexin type... 97.2 2e-19
sp|A0QNL1|MYCP1_MYCS2 Mycosin-1 OS=Mycolicibacterium smegmatis (s... 95.7 2e-19
sp|A8T682|PCSK9_SAGLB Proprotein convertase subtilisin/kexin type... 96.4 3e-19
sp|A8T655|PCSK9_PANPA Proprotein convertase subtilisin/kexin type... 96.0 4e-19
sp|E6MVD9|NALP_NEIMH Neisserial autotransporter lipoprotein NalP ... 96.4 4e-19
sp|P15293|P2P_LACLC PII-type proteinase OS=Lactococcus lactis sub... 95.7 1e-18
sp|A8T658|PCSK9_PONPY Proprotein convertase subtilisin/kexin type... 94.5 1e-18
sp|P16271|P1P_LACLC PI-type proteinase OS=Lactococcus lactis subs... 95.3 1e-18
sp|P15292|P3P_LACLS PIII-type proteinase OS=Lactococcus lactis su... 94.9 2e-18
sp|Q9JXM7|NALP_NEIMB Neisserial autotransporter lipoprotein NalP ... 94.1 3e-18
sp|Q02470|P2P_LACPA PII-type proteinase OS=Lacticaseibacillus par... 93.7 4e-18
sp|I6YC58|MYCP4_MYCTU Mycosin-4 OS=Mycobacterium tuberculosis (st... 90.6 8e-18
sp|O05461|MYCP1_MYCTU Mycosin-1 OS=Mycobacterium tuberculosis (st... 89.1 3e-17
sp|Q6ESI7|TPPII_ORYSJ Tripeptidyl-peptidase 2 OS=Oryza sativa sub... 89.9 5e-17
sp|F4JVN6|TPPII_ARATH Tripeptidyl-peptidase 2 OS=Arabidopsis thal... 87.9 2e-16
sp|P29144|TPP2_HUMAN Tripeptidyl-peptidase 2 OS=Homo sapiens OX=9... 84.5 2e-15
sp|A9QY38|SBT4_LOTJA Subtilisin-like protease 4 OS=Lotus japonicu... 84.1 2e-15
sp|Q64560|TPP2_RAT Tripeptidyl-peptidase 2 OS=Rattus norvegicus O... 84.1 3e-15
sp|Q64514|TPP2_MOUSE Tripeptidyl-peptidase 2 OS=Mus musculus OX=1... 84.1 3e-15
sp|A5PK39|TPP2_BOVIN Tripeptidyl-peptidase 2 OS=Bos taurus OX=991... 83.7 4e-15
sp|Q09541|TPP2_CAEEL Tripeptidyl-peptidase 2 OS=Caenorhabditis el... 82.9 8e-15
sp|P31631|SSA1_MANHA Serotype-specific antigen 1 OS=Mannheimia ha... 81.0 2e-14
sp|Q9UT05|TPP2_SCHPO Tripeptidyl-peptidase 2 homolog OS=Schizosac... 78.7 1e-13
sp|O64495|SBT12_ARATH Subtilisin-like protease SBT1.2 OS=Arabidop... 76.4 6e-13
sp|Q9V6K1|TPP2_DROME Tripeptidyl-peptidase 2 OS=Drosophila melano... 74.9 2e-12
sp|Q9SA75|SBT21_ARATH Subtilisin-like protease SBT2.1 OS=Arabidop... 74.5 3e-12
sp|O64481|SBT25_ARATH Subtilisin-like protease SBT2.5 OS=Arabidop... 74.1 3e-12
sp|A9QY39|SBT3_LOTJA Subtilisin-like protease 3 OS=Lotus japonicu... 72.9 7e-12
sp|Q9SUN6|SBT22_ARATH Subtilisin-like protease SBT2.2 OS=Arabidop... 71.8 1e-11
sp|Q9FI12|SBT23_ARATH Subtilisin-like protease SBT2.3 OS=Arabidop... 71.4 2e-11
sp|Q9SZY2|SBT37_ARATH Subtilisin-like protease SBT3.7 OS=Arabidop... 71.4 2e-11
sp|O53945|MYCP5_MYCTU Mycosin-5 OS=Mycobacterium tuberculosis (st... 69.5 7e-11
sp|A0A0M3R8G2|SBT_PETHY Subtilisin-like protease OS=Petunia hybri... 68.3 2e-10
sp|Q9ZUF6|SBT18_ARATH Subtilisin-like protease SBT1.8 OS=Arabidop... 67.5 3e-10
sp|Q86XX4|FRAS1_HUMAN Extracellular matrix organizing protein FRA... 67.9 3e-10
sp|Q6EZC2|SUBA_ECOLX Subtilase cytotoxin subunit A OS=Escherichia... 66.0 4e-10
sp|O82777|SBT3_SOLLC Subtilisin-like protease SBT3 OS=Solanum lyc... 65.6 1e-09
sp|O49607|SBT16_ARATH Subtilisin-like protease SBT1.6 OS=Arabidop... 65.6 1e-09
sp|Q9FHA4|SBT19_ARATH Subtilisin-like protease SBT1.9 OS=Arabidop... 65.2 2e-09
sp|Q8SS86|SPL2_ENCCU Putative subtilisin-like proteinase 2 OS=Enc... 63.7 4e-09
sp|F4HYR6|SBT24_ARATH Subtilisin-like protease SBT2.4 OS=Arabidop... 63.3 7e-09
sp|Q8I430|SUB3_PLAF7 Subtilisin-like protease 3 OS=Plasmodium fal... 61.8 2e-08
sp|P81715|LIE1_STREX Leupeptin-inactivating enzyme 1 OS=Streptomy... 61.0 2e-08
sp|A9QY40|SBT1_LOTJA Subtilisin-like protease 1 OS=Lotus japonicu... 61.4 2e-08
sp|Q9LVJ1|SBT14_ARATH Subtilisin-like protease SBT1.4 OS=Arabidop... 61.4 3e-08
sp|Q9ZSB1|SBT3A_ARATH Subtilisin-like protease SBT3.10 OS=Arabido... 61.0 4e-08
sp|O05458|MYCP2_MYCTU Mycosin-2 OS=Mycobacterium tuberculosis (st... 60.2 5e-08
sp|P0DW09|HETQ2_PODAS Subtilisin-like protease het-Q2 OS=Podospor... 59.4 6e-08
sp|Q9ZSB0|SBT39_ARATH Subtilisin-like protease SBT3.9 OS=Arabidop... 59.8 9e-08
sp|Q9LZS6|SBT4F_ARATH Subtilisin-like protease SBT4.15 OS=Arabido... 59.4 9e-08
sp|A9JQS7|SBTS_LOTJA Subtilisin-like serine-protease S OS=Lotus j... 59.4 9e-08
sp|P80561|APX_STRGG Aminopeptidase S OS=Streptomyces griseus subs... 59.1 9e-08
sp|Q9GTN7|TAGA_DICDI Serine protease/ABC transporter B family pro... 59.8 1e-07
sp|Q9MAP4|SBT32_ARATH Subtilisin-like protease SBT3.2 OS=Arabidop... 59.1 1e-07
sp|P26842|CD27_HUMAN CD27 antigen OS=Homo sapiens OX=9606 GN=CD27... 57.1 1e-07
sp|Q9FIM8|SBT4A_ARATH Subtilisin-like protease SBT4.10 OS=Arabido... 59.1 1e-07
sp|G7KEU7|SBT_MEDTR Subtilisin-like protease OS=Medicago truncatu... 58.7 2e-07
sp|Q39547|CUCM1_CUCME Cucumisin OS=Cucumis melo OX=3656 PE=1 SV=1 58.7 2e-07
sp|Q9MAP5|SBT33_ARATH Subtilisin-like protease SBT3.3 OS=Arabidop... 58.7 2e-07
sp|Q9FLI4|SBT13_ARATH Subtilisin-like protease SBT1.3 OS=Arabidop... 58.7 2e-07
sp|F4KGD4|SBT47_ARATH Subtilisin-like protease SBT4.7 OS=Arabidop... 58.3 2e-07
sp|P0DD35|C5AP_STRPQ C5a peptidase OS=Streptococcus pyogenes sero... 58.7 2e-07
sp|P0DD34|C5AP_STRP3 C5a peptidase OS=Streptococcus pyogenes sero... 58.7 2e-07
sp|Q8GWX9|SBT3G_ARATH Subtilisin-like protease SBT3.16 OS=Arabido... 58.3 2e-07
sp|F4JJH4|SBT31_ARATH Subtilisin-like protease SBT3.1 OS=Arabidop... 57.9 3e-07
sp|P58099|C5AP_STRP1 C5a peptidase OS=Streptococcus pyogenes sero... 57.9 3e-07
sp|Q8NZ80|C5AP_STRP8 C5a peptidase OS=Streptococcus pyogenes sero... 57.9 3e-07
sp|F4HPF1|SBT34_ARATH Subtilisin-like protease SBT3.4 OS=Arabidop... 57.5 4e-07
sp|Q9C7U8|SBT3H_ARATH Subtilisin-like protease SBT3.17 OS=Arabido... 57.5 4e-07
sp|Q5X9R0|C5AP_STRP6 C5a peptidase OS=Streptococcus pyogenes sero... 57.5 5e-07
sp|I1N462|SBT1_SOYBN Subtilisin-like protease Glyma18g48580 OS=Gl... 56.7 6e-07
sp|P15926|C5AP_STRPY C5a peptidase OS=Streptococcus pyogenes OX=1... 56.7 8e-07
sp|Q8GUK4|SBT3D_ARATH Subtilisin-like protease SBT3.13 OS=Arabido... 56.4 8e-07
sp|F4JA91|SBT45_ARATH Subtilisin-like protease SBT4.5 OS=Arabidop... 56.4 9e-07
sp|Q9SZY3|SBT38_ARATH Subtilisin-like protease SBT3.8 OS=Arabidop... 56.4 1e-06
sp|Q9FIG2|SBT4D_ARATH Subtilisin-like protease SBT4.13 OS=Arabido... 56.0 1e-06
sp|Q8L7I2|SBT36_ARATH Subtilisin-like protease SBT3.6 OS=Arabidop... 56.0 1e-06
sp|F4JXC5|SBT54_ARATH Subtilisin-like protease SBT5.4 OS=Arabidop... 55.6 2e-06
sp|Q9MAP7|SBT35_ARATH Subtilisin-like protease SBT3.5 OS=Arabidop... 55.6 2e-06
sp|Q84WS0|SBT11_ARATH Subtilisin-like protease SBT1.1 OS=Arabidop... 55.6 2e-06
sp|Q8T9W1|TAGD_DICDI Serine protease/ABC transporter B family pro... 55.6 2e-06
sp|Q9LNU1|CRSP_ARATH CO(2)-response secreted protease OS=Arabidop... 55.2 2e-06
sp|Q9SVT4|SBT3E_ARATH Subtilisin-like protease SBT3.14 OS=Arabido... 54.8 2e-06
sp|Q9LUM3|SBT15_ARATH Subtilisin-like protease SBT1.5 OS=Arabidop... 54.4 3e-06
sp|F4JJL8|SBT3F_ARATH Subtilisin-like protease SBT3.15 OS=Arabido... 54.4 4e-06
sp|P83543|TAMP_STRMB Transglutaminase-activating metalloprotease ... 54.1 5e-06
sp|Q9FIM5|SBT49_ARATH Subtilisin-like protease SBT4.9 OS=Arabidop... 53.7 6e-06
sp|Q9FGU3|SBT44_ARATH Subtilisin-like protease SBT4.4 OS=Arabidop... 53.7 6e-06
sp|Q8L7D2|SBT4C_ARATH Subtilisin-like protease SBT4.12 OS=Arabido... 53.3 8e-06
sp|Q9FIF8|SBT43_ARATH Subtilisin-like protease SBT4.3 OS=Arabidop... 53.3 9e-06
sp|P0CY46|EGFR_APIME Epidermal growth factor receptor OS=Apis mel... 52.9 1e-05
sp|F4HSQ2|SBT51_ARATH Subtilisin-like protease SBT5.1 OS=Arabidop... 52.5 1e-05
sp|Q9STF7|SBT46_ARATH Subtilisin-like protease SBT4.6 OS=Arabidop... 52.5 2e-05
sp|P54683|TAGB_DICDI Serine protease/ABC transporter B family pro... 52.1 2e-05
sp|Q9FIM6|SBT48_ARATH Subtilisin-like protease SBT4.8 OS=Arabidop... 51.4 3e-05
sp|Q03185|TS11_GIAIN Major surface trophozoite antigen 11 OS=Giar... 50.6 6e-05
sp|Q23868|TAGC_DICDI Serine protease/ABC transporter B family pro... 50.6 7e-05
sp|Q9STQ2|SBT3I_ARATH Subtilisin-like protease SBT3.18 OS=Arabido... 49.8 9e-05
sp|Q1PDX5|SBT3B_ARATH Subtilisin-like protease SBT3.11 OS=Arabido... 49.8 9e-05
sp|Q5R328|RSPO3_DANRE R-spondin-3 OS=Danio rerio OX=7955 GN=rspo3... 48.3 1e-04
sp|Q9FIG1|SBT4B_ARATH Subtilisin-like protease SBT4.11 OS=Arabido... 48.7 2e-04
sp|Q9SZV5|SBT26_ARATH Subtilisin-like protease SBT2.6 OS=Arabidop... 48.3 3e-04
sp|O65351|SBT17_ARATH Subtilisin-like protease SBT1.7 OS=Arabidop... 48.3 3e-04
sp|P21849|TSA4_GIAIN Major surface-labeled trophozoite antigen 41... 47.5 4e-04
sp|F4JJH5|SBT3C_ARATH Subtilisin-like protease SBT3.12 OS=Arabido... 47.5 5e-04
sp|Q5XH36|CRE2A_XENLA Cysteine-rich with EGF-like domain protein ... 46.7 6e-04
sp|Q9LLL8|SBT4E_ARATH Subtilisin-like protease SBT4.14 OS=Arabido... 47.1 6e-04
sp|Q9FK76|SBT56_ARATH Subtilisin-like protease SBT5.6 OS=Arabidop... 47.1 6e-04
sp|Q60553|ERBB2_MESAU Receptor tyrosine-protein kinase erbB-2 OS=... 47.1 6e-04
sp|Q9ZSP5|AIR3_ARATH Subtilisin-like protease SBT5.3 OS=Arabidops... 47.1 7e-04
sp|Q6UXH1|CREL2_HUMAN Protein disulfide isomerase CRELD2 OS=Homo ... 46.0 9e-04
sp|P04412|EGFR_DROME Epidermal growth factor receptor OS=Drosophi... 46.3 0.001
sp|P70424|ERBB2_MOUSE Receptor tyrosine-protein kinase erbB-2 OS=... 46.0 0.001
sp|F4IG09|SBT41_ARATH Subtilisin-like protease SBT4.1 OS=Arabidop... 46.0 0.002
sp|Q4G063|CREL2_RAT Protein disulfide isomerase Creld2 OS=Rattus ... 45.2 0.002
sp|P06494|ERBB2_RAT Receptor tyrosine-protein kinase erbB-2 OS=Ra... 45.6 0.002
sp|Q5RB22|ERBB3_PONAB Receptor tyrosine-protein kinase erbB-3 OS=... 45.6 0.002
sp|P92127|VS41_GIAIN Variant-specific surface protein VSP4A1 OS=G... 45.6 0.002
sp|P21860|ERBB3_HUMAN Receptor tyrosine-protein kinase erbB-3 OS=... 45.6 0.002
sp|P25119|TNR1B_MOUSE Tumor necrosis factor receptor superfamily ... 44.8 0.002
sp|Q1RMU1|RSPO3_BOVIN R-spondin-3 OS=Bos taurus OX=9913 GN=RSPO3 ... 44.4 0.002
sp|Q4V7M2|CRE2B_XENLA Cysteine-rich with EGF-like domain protein ... 44.4 0.003
sp|Q2I0M5|RSPO4_HUMAN R-spondin-4 OS=Homo sapiens OX=9606 GN=RSPO... 43.7 0.003
sp|P24348|LET23_CAEEL Receptor tyrosine-protein kinase let-23 OS=... 44.8 0.004
sp|Q60438|CREL2_CRIGR Protein disulfide isomerase CRELD2 OS=Crice... 44.0 0.004
sp|Q55CT0|TPP1_DICDI Tripeptidyl-peptidase 1 OS=Dictyostelium dis... 44.0 0.005
sp|Q9BXY4|RSPO3_HUMAN R-spondin-3 OS=Homo sapiens OX=9606 GN=RSPO... 43.3 0.006
sp|Q61526|ERBB3_MOUSE Receptor tyrosine-protein kinase erbB-3 OS=... 44.0 0.006
sp|Q62799|ERBB3_RAT Receptor tyrosine-protein kinase erbB-3 OS=Ra... 43.7 0.007
sp|P04626|ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2 OS=... 43.7 0.008
sp|Q9CYA0|CREL2_MOUSE Protein disulfide isomerase Creld2 OS=Mus m... 43.3 0.008
sp|Q2KIT5|CREL2_BOVIN Protein disulfide isomerase CRELD2 OS=Bos t... 42.9 0.009
sp|O23357|SBT42_ARATH Subtilisin-like protease SBT4.2 OS=Arabidop... 43.3 0.010
sp|Q04721|NOTC2_HUMAN Neurogenic locus notch homolog protein 2 OS... 43.3 0.011
sp|Q2TJ95|RSPO3_MOUSE R-spondin-3 OS=Mus musculus OX=10090 GN=Rsp... 42.1 0.011
sp|Q61527|ERBB4_MOUSE Receptor tyrosine-protein kinase erbB-4 OS=... 43.3 0.012
sp|Q7SXF6|CREL2_DANRE Cysteine-rich with EGF-like domain protein ... 42.5 0.013
sp|O73559|CRMB_CWPXG Soluble TNF receptor II OS=Cowpox virus (str... 42.1 0.014
sp|Q28295|VWF_CANLF von Willebrand factor OS=Canis lupus familiar... 42.9 0.014
sp|Q15303|ERBB4_HUMAN Receptor tyrosine-protein kinase erbB-4 OS=... 42.9 0.016
sp|Q5M7L6|RSPO2_XENTR R-spondin-2 OS=Xenopus tropicalis OX=8364 G... 41.3 0.016
sp|Q5UQ50|COLL6_MIMIV Collagen-like protein 6 OS=Acanthamoeba pol... 42.5 0.017
sp|Q5EA46|CREL1_BOVIN Protein disulfide isomerase CRELD1 OS=Bos t... 42.1 0.018
sp|Q2MKA7|RSPO1_HUMAN R-spondin-1 OS=Homo sapiens OX=9606 GN=RSPO... 41.3 0.018
sp|O35516|NOTC2_MOUSE Neurogenic locus notch homolog protein 2 OS... 42.5 0.018
sp|O18735|ERBB2_CANLF Receptor tyrosine-protein kinase erbB-2 OS=... 42.5 0.019
sp|Q5UE90|RSPO2_XENLA R-spondin-2 OS=Xenopus laevis OX=8355 GN=rs... 41.3 0.020
sp|P13387|EGFR_CHICK Epidermal growth factor receptor (Fragment) ... 42.1 0.021
sp|Q5UNS9|COLL7_MIMIV Collagen-like protein 7 OS=Acanthamoeba pol... 42.1 0.024
sp|Q62956|ERBB4_RAT Receptor tyrosine-protein kinase erbB-4 OS=Ra... 42.1 0.024
sp|P42790|PICP_PSESR Pseudomonalisin OS=Pseudomonas sp. (strain 1... 41.7 0.029
sp|Q07627|KRA11_HUMAN Keratin-associated protein 1-1 OS=Homo sapi... 39.8 0.033
sp|Q8CJ69|BMPER_MOUSE BMP-binding endothelial regulator protein O... 41.3 0.034
sp|Q9QW30|NOTC2_RAT Neurogenic locus notch homolog protein 2 OS=R... 41.7 0.036
sp|F1LWT0|SIMC1_RAT SUMO-interacting motif-containing protein 1 O... 41.7 0.036
sp|Q4V7F2|CREL1_RAT Protein disulfide isomerase Creld1 OS=Rattus ... 41.0 0.038
sp|Q91XD7|CREL1_MOUSE Protein disulfide isomerase Creld1 OS=Mus m... 41.0 0.040
sp|Q8BJ73|RSPO4_MOUSE R-spondin-4 OS=Mus musculus OX=10090 GN=Rsp... 40.2 0.047
sp|P85156|ASE1_ACRSP Subtilisin-like serine protease AS-E1 (Fragm... 35.9 0.048
sp|Q01279|EGFR_MOUSE Epidermal growth factor receptor OS=Mus musc... 41.0 0.049
sp|Q8C3L1|SSUH2_MOUSE Protein SSUH2 homolog OS=Mus musculus OX=10... 40.2 0.066
sp|Q80V70|MEGF6_MOUSE Multiple epidermal growth factor-like domai... 40.6 0.066
sp|P55245|EGFR_MACMU Epidermal growth factor receptor OS=Macaca m... 40.6 0.066
sp|Q9XWD6|CED1_CAEEL Cell death abnormality protein 1 OS=Caenorha... 40.6 0.068
sp|Q8TE57|ATS16_HUMAN A disintegrin and metalloproteinase with th... 40.6 0.080
sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mu... 40.2 0.086
sp|Q5G872|SCUB2_DANRE Signal peptide, CUB and EGF-like domain-con... 40.2 0.089
sp|Q8N446|ZN843_HUMAN Zinc finger protein 843 OS=Homo sapiens OX=... 39.8 0.089
sp|F4KEL0|SBT55_ARATH Subtilisin-like protease SBT5.5 OS=Arabidop... 40.2 0.092
sp|Q96HD1|CREL1_HUMAN Protein disulfide isomerase CRELD1 OS=Homo ... 39.8 0.10
sp|Q9Y2M2|SSUH2_HUMAN Protein SSUH2 homolog OS=Homo sapiens OX=96... 39.4 0.11
sp|O88799|ZAN_MOUSE Zonadhesin OS=Mus musculus OX=10090 GN=Zan PE... 40.2 0.11
sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo sap... 39.8 0.13
sp|P58459|ATS10_MOUSE A disintegrin and metalloproteinase with th... 39.4 0.16
sp|P0DSV8|CRMB_VARV Cytokine response-modifying protein B OS=Vari... 39.0 0.16
sp|P0DSV7|CRMB_VAR67 Cytokine response-modifying protein B OS=Var... 39.0 0.16
sp|Q9Z132|RSPO1_MOUSE R-spondin-1 OS=Mus musculus OX=10090 GN=Rsp... 38.6 0.16
sp|Q60675|LAMA2_MOUSE Laminin subunit alpha-2 OS=Mus musculus OX=... 39.4 0.16
sp|O88281|MEGF6_RAT Multiple epidermal growth factor-like domains... 39.4 0.16
sp|A8MUX0|KR161_HUMAN Keratin-associated protein 16-1 OS=Homo sap... 39.0 0.16
sp|Q88WG0|ACCD2_LACPL Acetyl-coenzyme A carboxylase carboxyl tran... 38.6 0.17
sp|C6VQ34|ACCD2_LACPJ Acetyl-coenzyme A carboxylase carboxyl tran... 38.6 0.17
sp|Q9JLL0|CRIM1_MOUSE Cysteine-rich motor neuron 1 protein OS=Mus... 39.4 0.17
sp|O89943|TAT_HV1SE Protein Tat OS=Human immunodeficiency virus t... 35.9 0.20
sp|Q80T91|MEG11_MOUSE Multiple epidermal growth factor-like domai... 39.0 0.23
sp|Q5T870|PRR9_HUMAN Proline-rich protein 9 OS=Homo sapiens OX=96... 36.3 0.24
sp|A2A5X5|KR161_MOUSE Keratin-associated protein 16-1 OS=Mus musc... 38.6 0.25
sp|P98092|HMCT_BOMMO Hemocytin OS=Bombyx mori OX=7091 PE=2 SV=1 39.0 0.26
sp|P54643|SP87_DICDI Spore coat protein SP87 OS=Dictyostelium dis... 38.6 0.27
sp|Q02763|TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sapiens OX=9... 38.6 0.29
sp|Q9XF14|BSD2_MAIZE Protein BUNDLE SHEATH DEFECTIVE 2, chloropla... 36.3 0.30
sp|Q3U492|KCP_MOUSE Kielin/chordin-like protein OS=Mus musculus O... 38.6 0.30
sp|Q5ND28|SREC_MOUSE Scavenger receptor class F member 1 OS=Mus m... 38.3 0.32
sp|Q61001|LAMA5_MOUSE Laminin subunit alpha-5 OS=Mus musculus OX=... 38.6 0.32
sp|A6BM72|MEG11_HUMAN Multiple epidermal growth factor-like domai... 38.3 0.33
sp|Q8CIZ8|VWF_MOUSE von Willebrand factor OS=Mus musculus OX=1009... 38.3 0.35
sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiosto... 38.3 0.37
sp|Q8BFU0|RSPO2_MOUSE R-spondin-2 OS=Mus musculus OX=10090 GN=Rsp... 37.5 0.37
sp|Q9IBG7|KCP_XENLA Kielin/chordin-like protein OS=Xenopus laevis... 38.3 0.40
sp|Q8AWW5|CRIM1_CHICK Cysteine-rich motor neuron 1 protein OS=Gal... 38.3 0.41
sp|Q6UXX9|RSPO2_HUMAN R-spondin-2 OS=Homo sapiens OX=9606 GN=RSPO... 37.1 0.41
sp|Q9UK23|NAGPA_HUMAN N-acetylglucosamine-1-phosphodiester alpha-... 37.9 0.43
sp|Q67UE8|LYP4_ORYSJ LysM domain-containing GPI-anchored protein ... 37.5 0.46
sp|Q9L9F3|NOVO_STRNV 8-demethylnovobiocic acid C(8)-methyltransfe... 37.1 0.47
sp|B3EWZ3|CADN_ACRMI Coadhesin (Fragment) OS=Acropora millepora O... 37.9 0.48
sp|P29825|VT2_MYXVL Tumor necrosis factor soluble receptor OS=Myx... 37.1 0.51
sp|O15230|LAMA5_HUMAN Laminin subunit alpha-5 OS=Homo sapiens OX=... 37.9 0.52
sp|P68637|CRMB_CAMPS Soluble TNF receptor II OS=Camelpox virus (s... 37.1 0.54
sp|P68636|CRMB_CAMPM Soluble TNF receptor II OS=Camelpox virus (s... 37.1 0.54
sp|Q02858|TIE2_MOUSE Angiopoietin-1 receptor OS=Mus musculus OX=1... 37.5 0.57
sp|Q6ZWJ8|KCP_HUMAN Kielin/chordin-like protein OS=Homo sapiens O... 37.5 0.59
sp|Q92743|HTRA1_HUMAN Serine protease HTRA1 OS=Homo sapiens OX=96... 37.1 0.60
sp|Q06807|TIE2_BOVIN Angiopoietin-1 receptor OS=Bos taurus OX=991... 37.5 0.63
sp|Q8VHS2|CRUM1_MOUSE Protein crumbs homolog 1 OS=Mus musculus OX... 37.5 0.68
sp|O75095|MEGF6_HUMAN Multiple epidermal growth factor-like domai... 37.5 0.70
sp|Q9ULL8|SHRM4_HUMAN Protein Shroom4 OS=Homo sapiens OX=9606 GN=... 37.5 0.71
sp|P25118|TNR1A_MOUSE Tumor necrosis factor receptor superfamily ... 37.1 0.72
sp|P97525|TNR8_RAT Tumor necrosis factor receptor superfamily mem... 37.1 0.72
sp|P35556|FBN2_HUMAN Fibrillin-2 OS=Homo sapiens OX=9606 GN=FBN2 ... 37.5 0.72
sp|Q9R0B6|LAMC3_MOUSE Laminin subunit gamma-3 OS=Mus musculus OX=... 37.5 0.74
sp|Q1W617|SHRM4_MOUSE Protein Shroom4 OS=Mus musculus OX=10090 GN... 37.1 0.79
sp|Q9Y6N6|LAMC3_HUMAN Laminin subunit gamma-3 OS=Homo sapiens OX=... 37.1 0.83
sp|Q8VEA6|CRDL2_MOUSE Chordin-like protein 2 OS=Mus musculus OX=1... 36.7 0.90
sp|P13388|XMRK_XIPMA Melanoma receptor tyrosine-protein kinase OS... 37.1 0.90
sp|Q9GYK2|ITBL_CAEEL Uncharacterized integrin beta-like protein C... 36.3 0.99
sp|P60014|KR10A_HUMAN Keratin-associated protein 10-10 OS=Homo sa... 35.9 1.1
sp|P0C6B8|SVEP1_RAT Sushi, von Willebrand factor type A, EGF and ... 36.7 1.1
sp|Q6UY66|VGP_MABVO Envelope glycoprotein OS=Lake Victoria marbur... 36.3 1.1
sp|P50555|TNR1A_PIG Tumor necrosis factor receptor superfamily me... 36.3 1.1
sp|P60411|KR109_HUMAN Keratin-associated protein 10-9 OS=Homo sap... 35.9 1.1
sp|Q65169|VF602_ASFB7 Protein B602L OS=African swine fever virus ... 36.3 1.3
sp|Q5VY43|PEAR1_HUMAN Platelet endothelial aggregation receptor 1... 36.3 1.4
sp|Q9H324|ATS10_HUMAN A disintegrin and metalloproteinase with th... 36.3 1.4
sp|P0DTN0|CRMB_MONPV Soluble TNF receptor II OS=Monkeypox virus O... 35.9 1.5
sp|A8XMW6|CED1_CAEBR Cell death abnormality protein 1 OS=Caenorha... 36.3 1.5
sp|A2A5X4|KR291_MOUSE Keratin-associated protein 29-1 OS=Mus musc... 35.6 1.9
sp|P15636|API_ACHLY Protease 1 OS=Achromobacter lyticus OX=224 PE... 35.6 2.0
sp|P35590|TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Ho... 35.9 2.1
sp|P98167|SSPO_BOVIN SCO-spondin OS=Bos taurus OX=9913 GN=SSPO PE... 35.9 2.2
sp|Q06805|TIE1_BOVIN Tyrosine-protein kinase receptor Tie-1 OS=Bo... 35.6 2.2
sp|Q61292|LAMB2_MOUSE Laminin subunit beta-2 OS=Mus musculus OX=1... 35.6 2.3
sp|P36941|TNR3_HUMAN Tumor necrosis factor receptor superfamily m... 35.2 2.4
sp|Q6NYJ3|TE2IP_DANRE Telomeric repeat-binding factor 2-interacti... 35.6 2.4
sp|Q9H8U3|ZFAN3_HUMAN AN1-type zinc finger protein 3 OS=Homo sapi... 34.8 2.5
sp|A8MXZ3|KRA91_HUMAN Keratin-associated protein 9-1 OS=Homo sapi... 34.8 2.5
sp|Q93038|TNR25_HUMAN Tumor necrosis factor receptor superfamily ... 35.2 2.5
sp|Q700K0|SSPO_RAT SCO-spondin OS=Rattus norvegicus OX=10116 GN=S... 35.6 2.6
sp|Q5U2M7|ZFAN3_RAT AN1-type zinc finger protein 3 OS=Rattus norv... 34.8 2.6
sp|Q5KSL6|DGKK_HUMAN Diacylglycerol kinase kappa OS=Homo sapiens ... 35.6 2.7
sp|Q3V2C1|KRA93_MOUSE Keratin-associated protein 9-3 OS=Mus muscu... 33.6 2.8
sp|Q24SS4|DNAJ_DESHY Chaperone protein DnaJ OS=Desulfitobacterium... 34.8 2.8
sp|B8FUN3|DNAJ_DESHD Chaperone protein DnaJ OS=Desulfitobacterium... 34.8 2.8
sp|Q3UHD1|AGRB1_MOUSE Adhesion G protein-coupled receptor B1 OS=M... 35.2 3.4
sp|Q24025|SOG_DROME Dorsal-ventral patterning protein Sog OS=Dros... 35.2 3.4
sp|C0HL12|AGRB1_RAT Adhesion G protein-coupled receptor B1 OS=Rat... 35.2 3.4
sp|Q66J85|ZFAN3_XENLA AN1-type zinc finger protein 3 homolog OS=X... 34.0 3.5
sp|Q197F5|005L_IIV3 Uncharacterized protein 005L OS=Invertebrate ... 34.0 3.5
sp|Q8BH27|MEGF9_MOUSE Multiple epidermal growth factor-like domai... 34.8 3.6
sp|P60412|KR10B_HUMAN Keratin-associated protein 10-11 OS=Homo sa... 34.4 3.7
sp|P14328|SP96_DICDI Spore coat protein SP96 OS=Dictyostelium dis... 34.8 3.8
sp|Q6IEK5|WRK76_ORYSI WRKY transcription factor WRKY76 OS=Oryza s... 34.4 3.8
sp|Q497H0|ZFAN3_MOUSE AN1-type zinc finger protein 3 OS=Mus muscu... 34.0 3.9
sp|P97677|DLL1_RAT Delta-like protein 1 OS=Rattus norvegicus OX=1... 34.8 4.4
sp|P60409|KR107_HUMAN Keratin-associated protein 10-7 OS=Homo sap... 34.0 4.9
sp|Q8WXS8|ATS14_HUMAN A disintegrin and metalloproteinase with th... 34.4 5.1
sp|P43489|TNR4_HUMAN Tumor necrosis factor receptor superfamily m... 34.0 5.4
sp|P15800|LAMB2_RAT Laminin subunit beta-2 OS=Rattus norvegicus O... 34.4 5.8
sp|O43593|HAIR_HUMAN Lysine-specific demethylase hairless OS=Homo... 34.4 6.0
sp|Q8K3K1|USH2A_RAT Usherin OS=Rattus norvegicus OX=10116 GN=Ush2... 34.4 6.2
sp|B2RUR4|KPRP_MOUSE Keratinocyte proline-rich protein OS=Mus mus... 33.6 9.8
>sp|P23188|FURIN_MOUSE Furin OS=Mus musculus OX=10090 GN=Furin
PE=1 SV=2
Length=793
Score = 1212 bits (3135), Expect = 0.0, Method: Composition-based stats.
Identities = 745/794 (94%), Positives = 760/794 (96%), Gaps = 1/794 (0%)
Query 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI 60
MELR WLLWVVAA G +VLLAADAQGQK+FTNTWAV IPGGPAVA+ VA+KHGF NLGQI
Sbjct 1 MELRSWLLWVVAAAGAVVLLAADAQGQKIFTNTWAVHIPGGPAVADRVAQKHGFHNLGQI 60
Query 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
FGDYYHFWHR VTKRSLSPHRPRHSRLQREPQV+WLEQQVAKRR KRDVYQEPTDPKFPQ
Sbjct 61 FGDYYHFWHRAVTKRSLSPHRPRHSRLQREPQVKWLEQQVAKRRAKRDVYQEPTDPKFPQ 120
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
QWYLSGVTQRDLNVK AWAQG+TGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP
Sbjct 121 QWYLSGVTQRDLNVKEAWAQGFTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
Query 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL
Sbjct 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH
Sbjct 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
Query 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC
Sbjct 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA+DWATNGVGRKV
Sbjct 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNADDWATNGVGRKV 420
Query 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH 480
SHSYGYGLLDAGAMVALAQNWTTVAPQRKCI++IL EPKDIGKRLEVRK VTACLGEPNH
Sbjct 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIVEILVEPKDIGKRLEVRKAVTACLGEPNH 480
Query 481 ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
ITRLEH QARLTLSYNRRGDLAIHL+SPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD
Sbjct 481 ITRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
Query 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCE 600
EDP+GEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGL PPESSGCKTLTSSQACVVCE
Sbjct 541 EDPAGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLSTPPESSGCKTLTSSQACVVCE 600
Query 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL 660
EG+SLHQKSCVQHCPPGF PQVLDTHYSTENDVE IRASVC PCHASCATCQGPA TDCL
Sbjct 601 EGYSLHQKSCVQHCPPGFIPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCL 660
Query 661 SCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGL 720
SCPSHASLDPVEQTCSRQSQSSRES PQQQPP L PEVE RL+AG L SHLPEV+AGL
Sbjct 661 SCPSHASLDPVEQTCSRQSQSSRESRPQQQPPALRPEVEMEPRLQAG-LASHLPEVLAGL 719
Query 721 SCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG 780
SC IVL+F VFL L SGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG
Sbjct 720 SCLIIVLIFGIVFLFLHRCSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG 779
Query 781 RGERTAFIKDQSAL 794
RGERTAFIKDQSAL
Sbjct 780 RGERTAFIKDQSAL 793
>sp|P09958|FURIN_HUMAN Furin OS=Homo sapiens OX=9606 GN=FURIN
PE=1 SV=2
Length=794
Score = 1201 bits (3106), Expect = 0.0, Method: Composition-based stats.
Identities = 794/794 (100%), Positives = 794/794 (100%), Gaps = 0/794 (0%)
Query 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI 60
MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI
Sbjct 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI 60
Query 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ
Sbjct 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP
Sbjct 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
Query 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL
Sbjct 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH
Sbjct 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
Query 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC
Sbjct 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV
Sbjct 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
Query 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH 480
SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH
Sbjct 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH 480
Query 481 ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD
Sbjct 481 ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
Query 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCE 600
EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCE
Sbjct 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCE 600
Query 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL 660
EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL
Sbjct 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL 660
Query 661 SCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGL 720
SCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGL
Sbjct 661 SCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGL 720
Query 721 SCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG 780
SCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG
Sbjct 721 SCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG 780
Query 781 RGERTAFIKDQSAL 794
RGERTAFIKDQSAL
Sbjct 781 RGERTAFIKDQSAL 794
>sp|P23377|FURIN_RAT Furin OS=Rattus norvegicus OX=10116 GN=Furin
PE=1 SV=1
Length=793
Score = 1200 bits (3105), Expect = 0.0, Method: Composition-based stats.
Identities = 744/794 (94%), Positives = 756/794 (95%), Gaps = 1/794 (0%)
Query 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI 60
MELRPWLLWVVAA G LVLLAA+A+GQK+FTNTWAV I GGPAVA+SVARKHGF NLGQI
Sbjct 1 MELRPWLLWVVAAAGALVLLAAEARGQKIFTNTWAVHISGGPAVADSVARKHGFHNLGQI 60
Query 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
FGDYYHFWHR VTKRSLSPHRPRHSRLQR PQV+WLEQQVAK+R KRDVYQEPTDPKFPQ
Sbjct 61 FGDYYHFWHRAVTKRSLSPHRPRHSRLQRVPQVKWLEQQVAKQRAKRDVYQEPTDPKFPQ 120
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
QWYLSGVTQRDLNVK AWAQG+TG GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP
Sbjct 121 QWYLSGVTQRDLNVKEAWAQGFTGRGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
Query 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL
Sbjct 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH
Sbjct 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
Query 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC
Sbjct 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV
Sbjct 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
Query 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH 480
SHSYGYGLLDAGAMVALAQNWTTVAPQRKCII+IL EPKDIGKRLEVRKTVTACLGEPNH
Sbjct 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIEILAEPKDIGKRLEVRKTVTACLGEPNH 480
Query 481 ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
I+RLEH QARLTLSYNRRGDLAIHL+SPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD
Sbjct 481 ISRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
Query 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCE 600
EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTA EGL PPESSGCKTLTSSQACVVCE
Sbjct 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTASEGLSAPPESSGCKTLTSSQACVVCE 600
Query 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL 660
EGFSLHQKSCVQ CPPGF PQVLDTHYSTENDVE IRASVC PCHASCATCQGPA TDCL
Sbjct 601 EGFSLHQKSCVQRCPPGFTPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCL 660
Query 661 SCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGL 720
SCPSHASLDPVEQTCSRQSQSSRES PQQ PP L PEVE RLRAG L SHLPEV+AGL
Sbjct 661 SCPSHASLDPVEQTCSRQSQSSRESRPQQPPPALRPEVEVEPRLRAG-LASHLPEVLAGL 719
Query 721 SCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG 780
SC I L+F VFL L SGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG
Sbjct 720 SCLIIALIFGIVFLFLHRCSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEG 779
Query 781 RGERTAFIKDQSAL 794
RGERTAFIKDQSAL
Sbjct 780 RGERTAFIKDQSAL 793
>sp|Q28193|FURIN_BOVIN Furin OS=Bos taurus OX=9913 GN=FURIN PE=1
SV=1
Length=797
Score = 1196 bits (3095), Expect = 0.0, Method: Composition-based stats.
Identities = 745/797 (93%), Positives = 757/797 (95%), Gaps = 3/797 (0%)
Query 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI 60
MELRPWL WVVAA G LVLL ADA+G+KVFTNTWAV IPGGPAVA+ VARKHGFLNLGQI
Sbjct 1 MELRPWLFWVVAAAGALVLLVADARGEKVFTNTWAVHIPGGPAVADRVARKHGFLNLGQI 60
Query 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
FGDYYHFWHR VTKRSLSPHR H+RLQREPQV+WLEQQVAKRR KRD+YQEPTDPKFPQ
Sbjct 61 FGDYYHFWHRAVTKRSLSPHRLGHNRLQREPQVKWLEQQVAKRRAKRDIYQEPTDPKFPQ 120
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
QWYLSGVTQRDLNVK AWAQGYTG GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP
Sbjct 121 QWYLSGVTQRDLNVKEAWAQGYTGRGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
Query 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL
Sbjct 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
GLNPNHIHIYSASWGPEDDGKTVDGPA LAEEAFFRGVSQGRGGLGSIFVWASGNGGREH
Sbjct 241 GLNPNHIHIYSASWGPEDDGKTVDGPAHLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
Query 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC
Sbjct 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
TESHTGTSA APLAAGIIALTLEANKNLTWRDMQHLVV+TSKPAHLNANDWATNGVGRKV
Sbjct 361 TESHTGTSAFAPLAAGIIALTLEANKNLTWRDMQHLVVRTSKPAHLNANDWATNGVGRKV 420
Query 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH 480
SHSYGYGLLDAGAMVALAQNWTTVAPQRKC IDILTEPKDIGKRLEVRKTVTACLGEP+H
Sbjct 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCTIDILTEPKDIGKRLEVRKTVTACLGEPSH 480
Query 481 ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD
Sbjct 481 ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
Query 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCE 600
EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLP PPES GCKTLTSSQACVVCE
Sbjct 541 EDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPTPPESIGCKTLTSSQACVVCE 600
Query 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL 660
EGFSLHQK+CVQHCPPGFAPQVLDTHYSTENDVE IRASVC PCHASCATCQGPA TDCL
Sbjct 601 EGFSLHQKNCVQHCPPGFAPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCL 660
Query 661 SCPSHASLDPVEQTC---SRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVV 717
SCPSHASLDPVEQTC S+ S+ S + P P P EV RLRA LLPSHLPEVV
Sbjct 661 SCPSHASLDPVEQTCSRQSQSSRESHQQQPPPPPRPPPAEVATEPRLRADLLPSHLPEVV 720
Query 718 AGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEE 777
AGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEE
Sbjct 721 AGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEE 780
Query 778 DEGRGERTAFIKDQSAL 794
DEGRGERTAFIKDQSAL
Sbjct 781 DEGRGERTAFIKDQSAL 797
>sp|P29119|FURI1_XENLA Furin-1 OS=Xenopus laevis OX=8355 GN=furin
PE=2 SV=1
Length=783
Score = 1092 bits (2823), Expect = 0.0, Method: Composition-based stats.
Identities = 553/779 (71%), Positives = 634/779 (81%), Gaps = 13/779 (2%)
Query 18 VLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSL 77
+L + GQKV+TNTWA I GG A A+ + +K+GF+N G IF D+YHF HR V KRSL
Sbjct 16 SVLVEEITGQKVYTNTWAAHISGGSAEADRLCKKYGFINHGLIFEDHYHFSHRAVMKRSL 75
Query 78 SPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAA 137
+P R R L+REPQV WLEQQVAK+R KRD+Y +PTDPKF QQWYL + DL+VK A
Sbjct 76 TPKRTRQVLLKREPQVHWLEQQVAKKRKKRDIYTDPTDPKFMQQWYLLDTNRHDLHVKEA 135
Query 138 WAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTR 197
W QG+TG GIVVSILDDGIEKNHPDL NYDP AS+DVNDQDPDPQPRYTQ+NDNRHGTR
Sbjct 136 WEQGFTGKGIVVSILDDGIEKNHPDLQANYDPAASYDVNDQDPDPQPRYTQLNDNRHGTR 195
Query 198 CAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPE 257
CAGEVAAVANNG+CGVG+AYNA IGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPE
Sbjct 196 CAGEVAAVANNGICGVGIAYNANIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPE 255
Query 258 DDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSI 317
DDGKTVDGPA+LAEEAF+RGV+QGRGGLGSI+VWASGNGGREHDSCNCDGYTNSIYTLSI
Sbjct 256 DDGKTVDGPAKLAEEAFYRGVTQGRGGLGSIYVWASGNGGREHDSCNCDGYTNSIYTLSI 315
Query 318 SSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGI 377
SS TQ GNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCT+SHTGTSASAPLAAGI
Sbjct 316 SSTTQMGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTDSHTGTSASAPLAAGI 375
Query 378 IALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVAL 437
IAL LEANKNLTWRDMQHLVVQTS PA LNANDW TNGVGRKVSHSYGYGLLDAGAMVA+
Sbjct 376 IALALEANKNLTWRDMQHLVVQTSNPAGLNANDWITNGVGRKVSHSYGYGLLDAGAMVAM 435
Query 438 AQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNR 497
A+ W TV PQRK +IDIL+EPKDIGK LEVR+ V C G N+I+ LEH QARL+LSYN
Sbjct 436 AKTWVTVGPQRKYVIDILSEPKDIGKALEVRRKVEPCAGMSNYISTLEHVQARLSLSYNC 495
Query 498 RGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEA 557
RGDLAI+L SPMGTRS LLA RPHDYSADGFNDW+FMTTHSWDEDP+GEWVLEIEN S
Sbjct 496 RGDLAIYLTSPMGTRSCLLAPRPHDYSADGFNDWSFMTTHSWDEDPAGEWVLEIENVSNN 555
Query 558 NNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPG 617
NNYGTLT+F LVLYGTA EGL + G + + SSQ+C+VCEEG+ LHQKSC++ CP G
Sbjct 556 NNYGTLTQFVLVLYGTASEGLSRKFDGDGSRNVASSQSCIVCEEGYFLHQKSCIKSCPQG 615
Query 618 FAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSR 677
F + + HY+ +N++E + +VC PCH SCATC+G + DCL+CP+H+ + ++ +C+
Sbjct 616 FTSSIQNIHYTLDNNIEPLLVNVCVPCHVSCATCKGTTINDCLTCPAHSHYNLLDYSCTH 675
Query 678 QSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVTVFLVLQ 737
Q+Q SRESP + + R S+LP +VA LSC FI++VF ++FL LQ
Sbjct 676 QTQRSRESPTLKDSSH-----DYVAR------TSNLPFIVAILSCLFIIVVFGSIFLFLQ 724
Query 738 LRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDE--GRGERTAFIKDQSAL 794
LRSG ++Y +D G+ISYKG+P AWQEE S+SE +E ERTAF+K QS L
Sbjct 725 LRSGGVLGRKRLYMLDSGIISYKGIPSGAWQEEGFSESETEETAAHSERTAFLKQQSTL 783
>sp|P63239|NEC1_MOUSE Neuroendocrine convertase 1 OS=Mus musculus
OX=10090 GN=Pcsk1 PE=1 SV=1
Length=753
Score = 857 bits (2215), Expect = 0.0, Method: Composition-based stats.
Identities = 330/757 (44%), Positives = 453/757 (60%), Gaps = 52/757 (7%)
Query 1 MELRPWLLWVVAATGTLVLLAADA-QGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQ 59
ME R W L A V A ++ + ++ F N WA IPGG A+++A + G+ LGQ
Sbjct 1 MEQRGWTLQCTAFAFFCVWCALNSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQ 60
Query 60 I--FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP---- 113
I ++Y F H+ +RS RL + +V W EQQ K R+KR V ++
Sbjct 61 IGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDL 120
Query 114 -TDPKFPQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
DP + QQWYL + + + DL+V W +G TG G+V+++LDDG+E NH D+ N
Sbjct 121 FNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYAN 180
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
YDP AS+D ND D DP PRY N+N+HGTRCAGE+A ANN CGVGVAYN+++GG+RM
Sbjct 181 YDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM 240
Query 227 LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLG 286
LDG VTDA+EA S+G NP H+ IYSASWGP DDGKTV+GP RLA++AF GV QGR G G
Sbjct 241 LDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG 300
Query 287 SIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ 346
SIFVWASGNGGR+ D+C+CDGYT+SIYT+SISSA+Q G PWY+E CSSTLAT+YSSG+
Sbjct 301 SIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY 360
Query 347 NEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
+++I + DL CTE+HTGTSASAPLAAGI AL LEAN NLTWRDMQHLVV TS+ L
Sbjct 361 TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL 420
Query 407 NAN-DWATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCII-DILTEPKDIG 462
+N W NG G V+ +G+GLL+A A+V LA + W V +++C++ D EP+ +
Sbjct 421 ASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALK 480
Query 463 KRLE--VRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARP 520
E V AC G+ N I LEH Q T+ Y+RRGDL + L S +GT + LLA R
Sbjct 481 ANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERE 540
Query 521 HDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS-EANNYGTLTKFTLVLYGTA--PEG 577
D S +GF +W FM+ H+W E+P G W L+I + S N G + + L+L+GT+ PE
Sbjct 541 RDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEH 600
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
+ P + T+ + + V E+ ++ +K Q +++
Sbjct 601 MKQPRVYTSYNTVQNDRRGV--EKMVNVVEKRPTQ---------------------KSLN 637
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS---QSSRESPPQQQPPRL 694
++ P ++S + +G PS A L ++ S+ + QS ++SP +
Sbjct 638 GNLLVPKNSSSSNVEGRRDEQVQGTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPY 697
Query 695 PPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVT 731
EA ++L PS L L ++ + + T
Sbjct 698 ESFYEALEKLNK---PSKLEGSEDSLYSDYVDVFYNT 731
>sp|P63240|NEC1_MUSCO Neuroendocrine convertase 1 OS=Mus cookii
OX=10098 GN=Pcsk1 PE=2 SV=1
Length=753
Score = 857 bits (2213), Expect = 0.0, Method: Composition-based stats.
Identities = 330/757 (44%), Positives = 452/757 (60%), Gaps = 52/757 (7%)
Query 1 MELRPWLLWVVAATGTLVLLAADA-QGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQ 59
ME R W L A V A + + ++ F N WA IPGG A+++A + G+ LGQ
Sbjct 1 MEQRGWTLQCTAFAFFCVWCALSSVKAKRQFVNEWAAEIPGGQEAASAIAEELGYDLLGQ 60
Query 60 I--FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP---- 113
I ++Y F H+ +RS RL + +V W EQQ K R+KR V ++
Sbjct 61 IGSLENHYLFKHKSHPRRSRRSALHITKRLSDDDRVTWAEQQYEKERSKRSVQKDSALDL 120
Query 114 -TDPKFPQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
DP + QQWYL + + + DL+V W +G TG G+V+++LDDG+E NH D+ N
Sbjct 121 FNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWEKGITGKGVVITVLDDGLEWNHTDIYAN 180
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
YDP AS+D ND D DP PRY N+N+HGTRCAGE+A ANN CGVGVAYN+++GG+RM
Sbjct 181 YDPEASYDFNDNDHDPFPRYDLTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM 240
Query 227 LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLG 286
LDG VTDA+EA S+G NP H+ IYSASWGP DDGKTV+GP RLA++AF GV QGR G G
Sbjct 241 LDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG 300
Query 287 SIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ 346
SIFVWASGNGGR+ D+C+CDGYT+SIYT+SISSA+Q G PWY+E CSSTLAT+YSSG+
Sbjct 301 SIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY 360
Query 347 NEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
+++I + DL CTE+HTGTSASAPLAAGI AL LEAN NLTWRDMQHLVV TS+ L
Sbjct 361 TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL 420
Query 407 NAN-DWATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCII-DILTEPKDIG 462
+N W NG G V+ +G+GLL+A A+V LA + W V +++C++ D EP+ +
Sbjct 421 ASNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECVVKDNNFEPRALK 480
Query 463 KRLE--VRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARP 520
E V AC G+ N I LEH Q T+ Y+RRGDL + L S +GT + LLA R
Sbjct 481 ANGEVIVEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAVGTSTVLLAERE 540
Query 521 HDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS-EANNYGTLTKFTLVLYGTA--PEG 577
D S +GF +W FM+ H+W E+P G W L+I + S N G + + L+L+GT+ PE
Sbjct 541 RDTSPNGFKNWDFMSVHTWGENPVGTWTLKITDMSGRMQNEGRIVNWKLILHGTSSQPEH 600
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
+ P + T+ + + V E+ ++ +K Q +++
Sbjct 601 MKQPRVYTSYNTVQNDRRGV--EKMVNVVEKRPTQ---------------------KSLN 637
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS---QSSRESPPQQQPPRL 694
++ P ++S + +G PS A L ++ S+ + QS ++SP +
Sbjct 638 GNLLVPKNSSSSNVEGRRDEQVQGTPSKAMLRLLQSAFSKNALSKQSPKKSPSAKLSIPY 697
Query 695 PPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVT 731
EA ++L PS L L ++ + + T
Sbjct 698 ESFYEALEKLNK---PSKLEGSEDSLYSDYVDVFYNT 731
>sp|P28840|NEC1_RAT Neuroendocrine convertase 1 OS=Rattus norvegicus
OX=10116 GN=Pcsk1 PE=2 SV=1
Length=752
Score = 851 bits (2199), Expect = 0.0, Method: Composition-based stats.
Identities = 329/756 (44%), Positives = 451/756 (60%), Gaps = 51/756 (7%)
Query 1 MELRPWLLWVVAATGTLVLLAADA-QGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQ 59
M+ R W L A T V A ++ + ++ F N WA I GGP A+++A + G+ LGQ
Sbjct 1 MKQRGWTLQCTAFTLFCVWCALNSVKAKRQFVNEWAAEIHGGPEAASAIAEELGYDLLGQ 60
Query 60 I--FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP---- 113
I ++Y F H+ +RS RL + +V W EQQ K R KR V ++
Sbjct 61 IGSLENHYLFKHKNHPRRSRRSALHITKRLSDDDRVIWAEQQYEKERRKRSVPRDSALNL 120
Query 114 -TDPKFPQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
DP + QQWYL + + + DL+V W +G TG G+V+++LDDG+E NH D+ N
Sbjct 121 FNDPMWNQQWYLQDTRMTASLPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYAN 180
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
YDP AS+D ND D DP PRY N+N+HGTRCAGE+A ANN CGVGVAYN+++GG+RM
Sbjct 181 YDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM 240
Query 227 LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLG 286
LDG VTDA+EA S+G NP H+ IYSASWGP DDGKTV+GP RLA++AF GV QGR G G
Sbjct 241 LDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG 300
Query 287 SIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ 346
SIFVWASGNGGR+ D+C+CDGYT+SIYT+SISSA+Q G PWY+E CSSTLAT+YSSG+
Sbjct 301 SIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY 360
Query 347 NEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
+++I + DL CTE+HTGTSASAPLAAGI AL LEAN NLTWRDMQHLVV TS+ L
Sbjct 361 TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL 420
Query 407 -NANDWATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCII-DILTEPKDIG 462
N W NG G V+ +G+GLL+A A+V LA + W V +++CII D EP+ +
Sbjct 421 ANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECIIKDNNFEPRALK 480
Query 463 KRLE--VRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARP 520
E V AC G+ N I LEH Q T+ Y+RRGDL + L S GT + LLA R
Sbjct 481 ANGEVIVEIPTRACEGQENAINSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERE 540
Query 521 HDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS-EANNYGTLTKFTLVLYGTA--PEG 577
D S +GF +W FM+ H+W E+P G W L++ + S N G + + L+L+GT+ PE
Sbjct 541 RDTSPNGFKNWDFMSVHTWGENPVGTWTLKVTDMSGRMQNEGRIVNWKLILHGTSSQPEH 600
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
+ P + T+ + + V E+ ++ ++ Q+ ++
Sbjct 601 MKQPRVYTSYNTVQNDRRGV--EKMVNVVEEKPTQN---------------------SLN 637
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPE 697
++ P ++S ++ + PS A L ++ S+ + S + S +P E
Sbjct 638 GNLLVPKNSSSSSVEDRRDEQVQGAPSKAMLRLLQSAFSKNTPSKQSSKIPSAKLSVPYE 697
Query 698 --VEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVT 731
EA ++L PS L + L ++ + + T
Sbjct 698 GLYEALEKLNK---PSQLEDSEDSLYSDYVDVFYNT 730
>sp|Q6UW60|PCSK4_HUMAN Proprotein convertase subtilisin/kexin
type 4 OS=Homo sapiens OX=9606 GN=PCSK4 PE=1 SV=2
Length=755
Score = 847 bits (2189), Expect = 0.0, Method: Composition-based stats.
Identities = 392/708 (55%), Positives = 479/708 (68%), Gaps = 28/708 (4%)
Query 28 KVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGD--YYHFWHRGVTKRSLSPHRPRHS 85
++ ++WAV++ G +ARK GF+NLG IF D Y+H HRGV ++SL+PH
Sbjct 32 PIYVSSWAVQVSQGNREVERLARKFGFVNLGPIFPDGQYFHLRHRGVVQQSLTPHWGHRL 91
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
L++ P+VQW +QQ +RR KR V PTDP F +QWY++ Q DL++ AW+QG +G
Sbjct 92 HLKKNPKVQWFQQQTLQRRVKRSVVV-PTDPWFSKQWYMNSEAQPDLSILQAWSQGLSGQ 150
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
GIVVS+LDDGIEK+HPDL NYDP AS+D ND DPDPQPRYT +NRHGTRCAGEVAA+
Sbjct 151 GIVVSVLDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPSKENRHGTRCAGEVAAM 210
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDG 265
ANNG CGVGVA+NARIGGVRMLDG +TD +EA+SL L P HIHIYSASWGPEDDG+TVDG
Sbjct 211 ANNGFCGVGVAFNARIGGVRMLDGTITDVIEAQSLSLQPQHIHIYSASWGPEDDGRTVDG 270
Query 266 PARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGN 325
P L EAF RGV++GRGGLG++F+WASGNGG +D+CNCDGYTNSI+TLS+ S TQ G
Sbjct 271 PGILTREAFRRGVTKGRGGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTQQGR 330
Query 326 VPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEAN 385
VPWYSEAC+STL TTYSSG + QIVTTDL CT+ HTGTSASAPLAAG+IAL LEAN
Sbjct 331 VPWYSEACASTLTTTYSSGVATDPQIVTTDLHHGCTDQHTGTSASAPLAAGMIALALEAN 390
Query 386 KNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVA 445
LTWRDMQHLVV+ SKPAHL A DW TNGVGR+VSH YGYGLLDAG +V A+ W
Sbjct 391 PFLTWRDMQHLVVRASKPAHLQAEDWRTNGVGRQVSHHYGYGLLDAGLLVDTARTWLPTQ 450
Query 446 PQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHL 505
PQRKC + + + P I + +R+ V+AC G N I LEH QA+LTLSY+RRGDL I L
Sbjct 451 PQRKCAVRVQSRPTPILPLIYIRENVSACAGLHNSIRSLEHVQAQLTLSYSRRGDLEISL 510
Query 506 VSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTK 565
SPMGTRSTL+A RP D S +G+N+W FM+TH WDE+P G W L +EN N GTL +
Sbjct 511 TSPMGTRSTLVAIRPLDVSTEGYNNWVFMSTHFWDENPQGVWTLGLENKGYYFNTGTLYR 570
Query 566 FTLVLYGTAPE--GLPVPPE--SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQ 621
+TL+LYGTA + P P+ SS C + C C+ + + C+ +CPP F
Sbjct 571 YTLLLYGTAEDMTARPTGPQVTSSACVQRDTEGLCQACDGPAYILGQLCLAYCPPRFFNH 630
Query 622 V-LDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQ 680
L T +R VC+ CHASC TC+G + DC SCP ++LD + +C
Sbjct 631 TRLVTAGPGHTAAPALR--VCSSCHASCYTCRGGSPRDCTSCPPSSTLDQQQGSCM---- 684
Query 681 SSRESPPQQQPPRLPPEVEAGQRLRAGLLPSH-LPEVVAGLSCAFIVL 727
P RLRA P H P LS + L
Sbjct 685 ----GPTTPDSRP---------RLRAAACPHHRCPASAMVLSLLAVTL 719
>sp|Q63415|PCSK6_RAT Proprotein convertase subtilisin/kexin type
6 OS=Rattus norvegicus OX=10116 GN=Pcsk6 PE=1 SV=1
Length=937
Score = 846 bits (2184), Expect = 0.0, Method: Composition-based stats.
Identities = 351/729 (48%), Positives = 446/729 (61%), Gaps = 52/729 (7%)
Query 4 RPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--F 61
RPW ++ A + +A + V+TN WAV++ GGP A+ VA HG+LNLGQI
Sbjct 29 RPWRWLLLLALPAV--CSALPPPRPVYTNHWAVQVLGGPGAADRVAAAHGYLNLGQIGNL 86
Query 62 GDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP---TDPKF 118
DYYHF+H KRS R H+ L+ +PQV+WL+QQ KRR KR + DP +
Sbjct 87 DDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQARSDSLYFNDPIW 146
Query 119 PQQWYL-----SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
WY+ + + ++NV+AAW +GYTG +VV+ILDDGIE+NHPDLA NYD AS+
Sbjct 147 SNMWYMHCADKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASY 206
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTD 233
DVN D DP PRY N+N+HGTRCAGEVAA ANN C VG+AYNA+IGG+RMLDG+VTD
Sbjct 207 DVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTD 266
Query 234 AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWAS 293
VEA+SLG+ PN+I IYSASWGP+DDGKTVDGP RLA++AF G+ +GR GLGSIFVWAS
Sbjct 267 VVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWAS 326
Query 294 GNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVT 353
GNGGRE D C+CDGYTNSIYT+S+SS T+ G+ PWY E C+STLATTYSSG E++IVT
Sbjct 327 GNGGREGDHCSCDGYTNSIYTISVSSTTENGHKPWYLEECASTLATTYSSGAFYERKIVT 386
Query 354 TDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWAT 413
TDLRQ+CT+ HTGTS SAP+ AGIIAL LEAN LTWRD+QHL+V+TS+PAHL A+DW
Sbjct 387 TDLRQRCTDGHTGTSVSAPMVAGIIALALEANNQLTWRDVQHLLVKTSRPAHLKASDWKV 446
Query 414 NGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKT--V 471
NG G KVSH YG+GL+DA A+V A+ WT V Q C+ P+ I +R T
Sbjct 447 NGAGHKVSHLYGFGLVDAEALVLEARKWTAVPSQHMCVATADKRPRSIPVVQVLRTTALT 506
Query 472 TACLGEPNH-ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFND 530
AC + + LEH R+++S+ RRGDL IHL+SP GT+S LLA R D+S +GF +
Sbjct 507 NACADHSDQRVVYLEHVVVRISISHPRRGDLQIHLISPSGTKSQLLAKRLLDFSNEGFTN 566
Query 531 WAFMTTHSWDEDPSGEWVLEIEN----TSEANNYGTLTKFTLVLYGTAPEGLP------- 579
W FMT H W E GEW LE+++ G L +++L+LYGTA
Sbjct 567 WEFMTVHCWGEKAEGEWTLEVQDIPSQVRNPEKQGKLKEWSLILYGTAEHPYRTFSSHQS 626
Query 580 -----------VPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYS 628
P + + E H + + C A Q L+ +
Sbjct 627 RSRMLELSVPEQEPLKAEGPPPQAETPEEEEEYTGVCHPECGDKGCDGPSADQCLNCVHF 686
Query 629 TENDVETIRASV---------------CAPCHASCATCQGPALTDCLSCPSHASLDPVEQ 673
+ + +T R V C CH C TC G + T CLSC
Sbjct 687 SLGNSKTNRKCVSECPLGYFGDTAARRCRRCHKGCETCTGRSPTQCLSCRRGFYHHQETN 746
Query 674 TCSRQSQSS 682
TC +
Sbjct 747 TCVTLCPAG 755
Score = 51.0 bits (120), Expect = 4e-05, Method: Composition-based stats.
Identities = 29/105 (28%), Positives = 42/105 (40%), Gaps = 18/105 (17%)
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
L P C + + VC+EGFSL + SC+ C PG T++ +E
Sbjct 766 LRCHPSCQKC--VDEPEKSTVCKEGFSLARGSCIPDCEPG-------TYFDSE------- 809
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C CH +C TC GP+ +C+ C S + C
Sbjct 810 LIRCGECHHTCRTCVGPSREECIHC--AKSFHFQDWKCVPACGEG 852
Score = 46.0 bits (107), Expect = 0.001, Method: Composition-based stats.
Identities = 22/104 (21%), Positives = 39/104 (38%), Gaps = 17/104 (16%)
Query 586 GCKTLT--SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
C+T S + C+ C + F CV C GF ++ + VC
Sbjct 819 TCRTCVGPSREECIHCAKSFHFQDWKCVPACGEGFY----------PEEMPGLPHKVCRR 868
Query 644 CHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQ--SQSSRES 685
C +C +C+G + +C C A + +C ++ E+
Sbjct 869 CDENCLSCEGSS-RNCSRC--KAGFTQLGTSCITNHTCSNADET 909
>sp|P29122|PCSK6_HUMAN Proprotein convertase subtilisin/kexin
type 6 OS=Homo sapiens OX=9606 GN=PCSK6 PE=1 SV=1
Length=969
Score = 840 bits (2170), Expect = 0.0, Method: Composition-based stats.
Identities = 361/744 (49%), Positives = 450/744 (60%), Gaps = 68/744 (9%)
Query 4 RPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--F 61
RPW ++ A + + V+TN WAV++ GGPA A+ VA HG+LNLGQI
Sbjct 47 RPWRWLLLLALPAAC---SAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNL 103
Query 62 GDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP-----TDP 116
DYYHF+H KRS R H+ L+ +PQV+WL+QQ KRR KR V +P DP
Sbjct 104 EDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDP 163
Query 117 KFPQQWYL-----SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGA 171
+ WYL + + ++NV+AAW +GYTG +VV+ILDDGIE+NHPDLA NYD A
Sbjct 164 IWSNMWYLHCGDKNSRCRSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYA 223
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEV 231
S+DVN D DP PRY N+N+HGTRCAGEVAA ANN C VG+AYNA+IGG+RMLDG+V
Sbjct 224 SYDVNGNDYDPSPRYDASNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDV 283
Query 232 TDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVW 291
TD VEA+SLG+ PN+I IYSASWGP+DDGKTVDGP RLA++AF G+ +GR GLGSIFVW
Sbjct 284 TDVVEAKSLGIRPNYIDIYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVW 343
Query 292 ASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQI 351
ASGNGGRE D C+CDGYTNSIYT+S+SSAT+ G PWY E C+STLATTYSSG E++I
Sbjct 344 ASGNGGREGDYCSCDGYTNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKI 403
Query 352 VTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDW 411
VTTDLRQ+CT+ HTGTS SAP+ AGIIAL LEAN LTWRD+QHL+V+TS+PAHL A+DW
Sbjct 404 VTTDLRQRCTDGHTGTSVSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDW 463
Query 412 ATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKT- 470
NG G KVSH YG+GL+DA A+V A+ WT V Q C+ P+ I +R T
Sbjct 464 KVNGAGHKVSHFYGFGLVDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTA 523
Query 471 -VTACLGEPNH-ITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGF 528
+AC + + LEH R ++S+ RRGDL I+LVSP GT+S LLA R D S +GF
Sbjct 524 LTSACAEHSDQRVVYLEHVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGF 583
Query 529 NDWAFMTTHSWDEDPSGEWVLEIEN----TSEANNYGTLTKFTLVLYGT----------- 573
+W FMT H W E G+W LEI++ G L +++L+LYGT
Sbjct 584 TNWEFMTVHCWGEKAEGQWTLEIQDLPSQVRNPEKQGKLKEWSLILYGTAEHPYHTFSAH 643
Query 574 ----------APEGLPVP----------PESSGCKTLTSSQACVVCEEGFSLHQKSCVQH 613
APE P PE T S+ + H + +
Sbjct 644 QSRSRMLELSAPELEPPKAALSPSQVEVPEDEEDYTAQSTPGSANILQTSVCHPECGDKG 703
Query 614 CPPGFAPQVLDTHYSTENDVETIRASV---------------CAPCHASCATCQGPALTD 658
C A Q L+ + + V+T R V C CH C TC A T
Sbjct 704 CDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCETCSSRAATQ 763
Query 659 CLSCPSHASLDPVEQTCSRQSQSS 682
CLSC TC +
Sbjct 764 CLSCRRGFYHHQEMNTCVTLCPAG 787
Score = 52.5 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 29/105 (28%), Positives = 42/105 (40%), Gaps = 18/105 (17%)
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
L P C + + C VC+EGFSL + SC+ C PG T++ +E
Sbjct 798 LKCHPSCKKC--VDEPEKCTVCKEGFSLARGSCIPDCEPG-------TYFDSE------- 841
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C CH +C TC GP +C+ C + + C
Sbjct 842 LIRCGECHHTCGTCVGPGREECIHCAKNFHFH--DWKCVPACGEG 884
Score = 42.1 bits (97), Expect = 0.022, Method: Composition-based stats.
Identities = 21/100 (21%), Positives = 35/100 (35%), Gaps = 2/100 (2%)
Query 586 GCKTLTSSQA--CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
C T C+ C + F H CV C GF P+ + CA
Sbjct 851 TCGTCVGPGREECIHCAKNFHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAG 910
Query 644 CHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
+C+ C+ SC ++ + ++T +S+R
Sbjct 911 SSRNCSRCKTGFTQLGTSCITNHTCSNADETFCEMVKSNR 950
>sp|Q04592|PCSK5_MOUSE Proprotein convertase subtilisin/kexin
type 5 OS=Mus musculus OX=10090 GN=Pcsk5 PE=1 SV=3
Length=1877
Score = 827 bits (2135), Expect = 0.0, Method: Composition-based stats.
Identities = 359/731 (49%), Positives = 443/731 (61%), Gaps = 73/731 (10%)
Query 7 LLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--FGDY 64
LL V+A +L +V+TN WAV+I GG A A+ +A K+GF+N+GQI DY
Sbjct 17 LLCVLALLAGCLLPVCRT---RVYTNHWAVKIAGGFAEADRIASKYGFINVGQIGALKDY 73
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDV------YQEPTDPKF 118
YHF+H KRS+ R HS + EP+V+W++QQV K+RTKRD DPK+
Sbjct 74 YHFYHSRTIKRSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDLSHAQSTYFNDPKW 133
Query 119 PQQWYLS-----GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
P WY+ Q D+N++ AW +GYTG IVV+ILDDGIE+ HPDL NYD AS
Sbjct 134 PSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASC 193
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTD 233
DVN D DP PRY N+N+HGTRCAGEVAA ANN C VG+A+NA+IGGVRMLDG+VTD
Sbjct 194 DVNGNDLDPMPRYDASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDGDVTD 253
Query 234 AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWAS 293
VEA+S+ NP H+HIYSASWGP+DDGKTVDGPA L +AF GV GR GLGS+FVWAS
Sbjct 254 MVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWAS 313
Query 294 GNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVT 353
GNGGR D C+CDGYTNSIYT+SISS + G PWY E CSSTLATTYSSG +K+I+T
Sbjct 314 GNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIIT 373
Query 354 TDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWAT 413
TDLRQ+CT++HTGTSASAP+AAGIIAL LEAN LTWRD+QH++V+TS+ HLNANDW T
Sbjct 374 TDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKT 433
Query 414 NGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRK--TV 471
N G KVSH YG+GL+DA AMV A+ WTTV Q C+ + K I VR
Sbjct 434 NAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIRPNSAVRSIYKA 493
Query 472 TACLGEPN-HITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFND 530
+ C PN H+ LEH R+T+++ RRGDLAI+L SP GTRS LLA R D+S +GF +
Sbjct 494 SGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKN 553
Query 531 WAFMTTHSWDEDPSGEWVLEIENTSEA----NNYGTLTKFTLVLYGTAPEGL-------- 578
W FMT H W E +G+WVLE+ +T G L +++LVLYGT+ +
Sbjct 554 WEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPK 613
Query 579 -----------------------PVPPESS--GCKTLTSSQACVVCEEGFSLHQKS--CV 611
P PE S GC + L + CV
Sbjct 614 VERFRYSRVEDPTDDYGAEDYAGPCDPECSEVGCDGPGPDHCSDCLHYYYKLKNNTRICV 673
Query 612 QHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPV 671
CPPG HY + C C +C +C G CLSC L+
Sbjct 674 SSCPPG--------HYHADKK-------RCRKCAPNCESCFGSHGNQCLSCKYGYFLNEE 718
Query 672 EQTCSRQSQSS 682
+C Q
Sbjct 719 TSSCVTQCPDG 729
Score = 64.1 bits (154), Expect = 5e-09, Method: Composition-based stats.
Identities = 30/105 (29%), Positives = 41/105 (39%), Gaps = 17/105 (16%)
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
P + S C + Q C C L +CV+ CP G Y T+ D +
Sbjct 1495 QPCHKKCSRCSGPSEDQ-CYTCPRETFLLNTTCVKECPEG---------YHTDKDSQ--- 1541
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C CH+SC TC+GP CLSC + + C Q +
Sbjct 1542 --QCVLCHSSCRTCEGPHSMQCLSCRPGWF--QLGKECLLQCRDG 1582
Score = 63.7 bits (153), Expect = 7e-09, Method: Composition-based stats.
Identities = 31/105 (30%), Positives = 33/105 (31%), Gaps = 20/105 (19%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTE 630
+G E C C CEEGF L SCVQ C PGF
Sbjct 1078 FGVKWECRACGTNCGSCDQ----HECYWCEEGFFLSGGSCVQDCGPGFHGDQELGE---- 1129
Query 631 NDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTC 675
C PCH +C C G C SC L TC
Sbjct 1130 ----------CKPCHRACENCTGSGYNQCSSC--QEGLQLWHGTC 1162
Score = 63.7 bits (153), Expect = 7e-09, Method: Composition-based stats.
Identities = 25/108 (23%), Positives = 37/108 (34%), Gaps = 14/108 (13%)
Query 575 PEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
E C +S+ C+ C EGF++ C + Y E
Sbjct 1440 EENDECRDCPESCLICSSAWTCLACREGFTVVHDVCTAP------KECAAVEYWDEGS-- 1491
Query 635 TIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C PCH C+ C GP+ C +CP L + TC ++
Sbjct 1492 ----HRCQPCHKKCSRCSGPSEDQCYTCPRETFL--LNTTCVKECPEG 1533
Score = 61.4 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 27/113 (24%), Positives = 39/113 (35%), Gaps = 16/113 (14%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQA--CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYS 628
Y T + S C+T + C+ C G+ K C+ C G+ +
Sbjct 1534 YHTDKDSQQCVLCHSSCRTCEGPHSMQCLSCRPGWFQLGKECLLQCRDGYYGESTSG--- 1590
Query 629 TENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
C C SC +C+GP TDC SC + L + C R
Sbjct 1591 -----------RCEKCDKSCKSCRGPRPTDCQSCDTFFFLLRSKGQCHRACPE 1632
Score = 60.6 bits (145), Expect = 6e-08, Method: Composition-based stats.
Identities = 31/99 (31%), Positives = 43/99 (43%), Gaps = 14/99 (14%)
Query 579 PVPPESSGCKTLTSSQA--CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETI 636
P C T + + A C+ C EG+ + + CVQ C + +S+E ++
Sbjct 783 DCQPCHRFCATCSGAGADGCINCTEGYVMEEGRCVQSCSVSYYLD-----HSSEGGYKS- 836
Query 637 RASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTC 675
C C SC TC GP +C SCPS LD TC
Sbjct 837 ----CKRCDNSCLTCNGPGFKNCSSCPSGYLLDL--GTC 869
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 28/127 (22%), Positives = 40/127 (31%), Gaps = 8/127 (6%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTE 630
+G + P + + C C +H+K+C + C P F H S
Sbjct 1332 HGVCWKTCPEKHVAVEGVCKHCPERCQDC-----IHEKTC-KECMPDFFLYNDMCHRSCP 1385
Query 631 NDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQ 690
C PCH +C C GP DC C + S C + +
Sbjct 1386 KSFYP-DMRQCVPCHKNCLECNGPKEDDCKVC-ADTSKALHNGLCLDECPEGTYKEEEND 1443
Query 691 PPRLPPE 697
R PE
Sbjct 1444 ECRDCPE 1450
Score = 56.0 bits (133), Expect = 2e-06, Method: Composition-based stats.
Identities = 24/123 (20%), Positives = 41/123 (33%), Gaps = 21/123 (17%)
Query 575 PEGLPVPPESSGCKTLTSSQ---------ACVVCEEGFSLHQKSCVQHCPPGFAPQVLDT 625
PE + C+ + +C+ C + L + C+ C G +
Sbjct 1631 PEHYYADQHAQTCERCHPTCDKCSGKEAWSCLSCVWSYHLLKGICIPECIVGEYREGKGE 1690
Query 626 HYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRES 685
+++ C CH SC C+GP +C C + LD + C +S
Sbjct 1691 NFN------------CKKCHESCMECKGPGSKNCTGCSAGLLLDMDDNRCLHCCNASHSR 1738
Query 686 PPQ 688
Q
Sbjct 1739 RSQ 1741
Score = 52.5 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 25/130 (19%), Positives = 35/130 (27%), Gaps = 28/130 (22%)
Query 582 PESSGCKTLTSSQA---------CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEND 632
+ C+T +S A C+ C L CV +CP
Sbjct 882 DDQGHCQTCEASCAKCWGPTQEDCISCPVTRVLDDGRCVMNCP----------------S 925
Query 633 VETIRASVCAPCHASCATCQGPALTDCLSCPSHASLD---PVEQTCSRQSQSSRESPPQQ 689
+ C PCH +C CQG ++C SC + C
Sbjct 926 WKFEFKKQCHPCHYTCQGCQGSGPSNCTSCRADKHGQERFLYHGECLENCPVGHYPAKGH 985
Query 690 QPPRLPPEVE 699
P E
Sbjct 986 ACLPCPDNCE 995
Score = 51.0 bits (120), Expect = 5e-05, Method: Composition-based stats.
Identities = 28/103 (27%), Positives = 37/103 (36%), Gaps = 12/103 (12%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFA---PQVLDTHYSTENDVETIRASV 640
CK +S C+ C K+C CP G+ + +
Sbjct 834 YKSCKRCDNS--CLTCNGPGF---KNC-SSCPSGYLLDLGTCQMGAICKDGE-YIDDQGH 886
Query 641 CAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
C C ASCA C GP DC+SCP LD + C S +
Sbjct 887 CQTCEASCAKCWGPTQEDCISCPVTRVLD--DGRCVMNCPSWK 927
Score = 49.8 bits (117), Expect = 1e-04, Method: Composition-based stats.
Identities = 25/99 (25%), Positives = 31/99 (31%), Gaps = 18/99 (18%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
S CK C C+ G SL C C G C P
Sbjct 743 SENCKACIGFHNCTECKGGLSLQGSRCSVTCEDGQF----------------FNGHDCQP 786
Query 644 CHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
CH CATC G C++C ++ E C + S
Sbjct 787 CHRFCATCSGAGADGCINCTEGYVME--EGRCVQSCSVS 823
Score = 47.1 bits (110), Expect = 7e-04, Method: Composition-based stats.
Identities = 31/131 (24%), Positives = 42/131 (32%), Gaps = 24/131 (18%)
Query 570 LYGTAPEGLPVPPESSGCKTLTSSQ--ACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHY 627
+G E P C+ T S C C+EG L +C+ P + +
Sbjct 1121 FHG-DQELGECKPCHRACENCTGSGYNQCSSCQEGLQLWHGTCLWSTWPQVEGKDWNEAV 1179
Query 628 STEN----------------DVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPV 671
TE ++ S PCH+SC TC G C SCP+ L
Sbjct 1180 PTEKPSLVRSLLQDRRKWKVQIKRDATSQNQPCHSSCKTCNGSL---CASCPTGMYLWL- 1235
Query 672 EQTCSRQSQSS 682
Q C
Sbjct 1236 -QACVPSCPQG 1245
Score = 47.1 bits (110), Expect = 8e-04, Method: Composition-based stats.
Identities = 26/104 (25%), Positives = 34/104 (33%), Gaps = 23/104 (22%)
Query 584 SSGCKTLTSSQACVVCEE----GFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRAS 639
S C + + + C C LH+ C CP GF +
Sbjct 1259 SEDCVSCSGADLCQQCLSQPDNTLLLHEGRCYHSCPEGFYA----------------KDG 1302
Query 640 VCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
VC C + C TC+G A T C SC LD C +
Sbjct 1303 VCEHCSSPCKTCEGNA-TSCNSCEGDFVLD--HGVCWKTCPEKH 1343
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 21/105 (20%), Positives = 33/105 (31%), Gaps = 16/105 (15%)
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
LP P C+ + C C G+ + PP Q L+ + + +
Sbjct 988 LPCPD---NCELCYNPHVCSRCMSGYVI--------IPPNHTCQKLECR---QGEFQDSE 1033
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C PC C C C SC + + E+ C +
Sbjct 1034 YEECMPCEEGCLGCTEDDPGACTSCATGYYM--FERHCYKACPEK 1076
>sp|P41413|PCSK5_RAT Proprotein convertase subtilisin/kexin type
5 OS=Rattus norvegicus OX=10116 GN=Pcsk5 PE=2 SV=3
Length=1809
Score = 823 bits (2126), Expect = 0.0, Method: Composition-based stats.
Identities = 358/738 (49%), Positives = 445/738 (60%), Gaps = 73/738 (10%)
Query 7 LLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--FGDY 64
LL V+A +L +V+TN WAV+I GG A A+ +A K+GF+N+GQI DY
Sbjct 17 LLCVLALLAGCLLPVCRT---RVYTNHWAVKIAGGFAEADRIASKYGFINVGQIGALKDY 73
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDV------YQEPTDPKF 118
YHF+H KRS+ R HS + EP+V+W++QQV K+RTKRD DPK+
Sbjct 74 YHFYHSRTIKRSVLSSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDLSRAQSTYFNDPKW 133
Query 119 PQQWYLS-----GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
P WY+ Q D+N++ AW +GYTG IVV+ILDDGIE+ HPDL NYD AS
Sbjct 134 PSMWYMHCSDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASC 193
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTD 233
DVN D DP PRY N+N+HGTRCAGEVAA ANN C VG+A+NA+IGGVRMLDG+VTD
Sbjct 194 DVNGNDLDPMPRYDASNENKHGTRCAGEVAATANNSHCTVGIAFNAKIGGVRMLDGDVTD 253
Query 234 AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWAS 293
VEA+S+ NP H+HIYSASWGP+DDGKTVDGPA L +AF GV GR GLGS+FVWAS
Sbjct 254 MVEAKSVSYNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWAS 313
Query 294 GNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVT 353
GNGGR D C+CDGYTNSIYT+SISS + G PWY E CSSTLATTYSSG +K+I+T
Sbjct 314 GNGGRSKDHCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIIT 373
Query 354 TDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWAT 413
TDLRQ+CT++HTGTSASAP+AAGIIAL LEAN LTWRD+QH++V+TS+ HLNANDW T
Sbjct 374 TDLRQRCTDNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKT 433
Query 414 NGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRK--TV 471
N G KVSH YG+GL+DA AMV A+ WTTV Q C+ + K I VR
Sbjct 434 NAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHVCVESTDRQIKTIRPNSAVRSIYKA 493
Query 472 TACLGEPN-HITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFND 530
+ C PN H+ LEH R+T+++ RRGDLAI+L SP GTRS LLA R D+S +GF +
Sbjct 494 SGCSDNPNHHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKN 553
Query 531 WAFMTTHSWDEDPSGEWVLEIENTSEA----NNYGTLTKFTLVLYGTAPEGL-------- 578
W FMT H W E +G+WVLE+ +T G L +++LVLYGT+ +
Sbjct 554 WEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPK 613
Query 579 -----------------------PVPPESS--GCKTLTSSQACVVCEEGFSLHQKS--CV 611
P PE S GC + L + CV
Sbjct 614 VERFRYSRVEDPTDDYGAEDYAGPCDPECSEVGCDGPGPDHCTDCLHYHYKLKNNTRICV 673
Query 612 QHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPV 671
CPPG H+ + C C +C +C G CLSC L+
Sbjct 674 SSCPPG--------HFHADKK-------RCRKCAPNCESCFGSHADQCLSCKYGYFLNEE 718
Query 672 EQTCSRQSQSSRESPPQQ 689
+C Q ++
Sbjct 719 TSSCVAQCPEGSYQDIKK 736
Score = 67.1 bits (162), Expect = 5e-10, Method: Composition-based stats.
Identities = 30/105 (29%), Positives = 42/105 (40%), Gaps = 17/105 (16%)
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
P + S C + +Q C C L +CV+ CP G+ D+H
Sbjct 1426 QPCHRKCSRCSGPSENQ-CYTCPRETFLLNTTCVKECPEGYHTD-KDSH----------- 1472
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C PCH+SC TC+GP CLSC + + C Q +
Sbjct 1473 --QCVPCHSSCRTCEGPHSMQCLSCRPGWF--QLGKECLLQCRDG 1513
Score = 65.2 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 37/138 (27%), Positives = 43/138 (31%), Gaps = 22/138 (16%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTE 630
+G E C C CEEGF L SCVQ C PGF
Sbjct 1009 FGEKWECKACGTNCGSCDQ----HECYWCEEGFFLSSGSCVQDCDPGFYGDQELGE---- 1060
Query 631 NDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQ 690
C PCH +C TC G C SCP L TC + E +
Sbjct 1061 ----------CKPCHRACETCTGLGYNQCSSCPEG--LQLWHGTCIWPTWPHVEGKVWNE 1108
Query 691 PPRL--PPEVEAGQRLRA 706
P V + + R
Sbjct 1109 AVPTEKPSLVRSLPQDRR 1126
Score = 62.5 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 31/145 (21%), Positives = 46/145 (32%), Gaps = 39/145 (27%)
Query 538 SWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACV 597
DE P G + E+ + E P C +S+ C+
Sbjct 1359 CLDECPKGTYKDEVND----------------------ECRDCP---ESCLICSSAWTCL 1393
Query 598 VCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALT 657
C EGF++ Q C + Y C PCH C+ C GP+
Sbjct 1394 TCREGFTVVQDVCTAP------KECAAIEYWDVGS------HRCQPCHRKCSRCSGPSEN 1441
Query 658 DCLSCPSHASLDPVEQTCSRQSQSS 682
C +CP L + TC ++
Sbjct 1442 QCYTCPRETFL--LNTTCVKECPEG 1464
Score = 62.5 bits (150), Expect = 1e-08, Method: Composition-based stats.
Identities = 25/112 (22%), Positives = 39/112 (35%), Gaps = 8/112 (7%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTE 630
+G E P + + C C +H+K+C + C P F H+S
Sbjct 1263 HGVCWETCPEKHVAVEGVCKHCPERCQDC-----IHEKTC-KECMPDFFLYNDMCHHSCP 1316
Query 631 NDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
+ C PCH +C C GP DC +C + + C +
Sbjct 1317 KNFYP-DMRQCVPCHKNCLGCNGPKEDDCKACADTSKV-LHNGLCLDECPKG 1366
Score = 61.8 bits (148), Expect = 2e-08, Method: Composition-based stats.
Identities = 28/113 (25%), Positives = 39/113 (35%), Gaps = 16/113 (14%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQA--CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYS 628
Y T + P S C+T + C+ C G+ K C+ C G+ +
Sbjct 1465 YHTDKDSHQCVPCHSSCRTCEGPHSMQCLSCRPGWFQLGKECLLQCRDGYYGESTSG--- 1521
Query 629 TENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
C C SC TC+GP TDC SC + L + C
Sbjct 1522 -----------RCEKCDKSCKTCRGPQPTDCQSCDTFFFLLRSKGQCHLACPE 1563
Score = 59.8 bits (143), Expect = 9e-08, Method: Composition-based stats.
Identities = 31/101 (31%), Positives = 41/101 (41%), Gaps = 12/101 (12%)
Query 572 GTAPEGLPVPPESSGCKTLTSSQA--CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
G G P C T + A C+ C EG+ + + CVQ C + +S
Sbjct 776 GQFFSGHDCQPCHRFCATCAGAGADGCINCTEGYVMEEGRCVQSCSVSYYLD-----HSL 830
Query 630 ENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDP 670
E ++ C C SC TC GP +C SCPS LD
Sbjct 831 EGGYKS-----CKRCDNSCLTCNGPGFKNCSSCPSGYLLDL 866
Score = 53.7 bits (127), Expect = 7e-06, Method: Composition-based stats.
Identities = 24/123 (20%), Positives = 38/123 (31%), Gaps = 21/123 (17%)
Query 575 PEGLPVPPESSGCKTLTSSQ---------ACVVCEEGFSLHQKSCVQHCPPGFAPQVLDT 625
PE + C+ + C+ C + L + C C G
Sbjct 1562 PEHYYADQHAQTCERCHPTCDKCSGKEAWNCLSCVWSYHLLKGICTPECIVGEYRDGKGE 1621
Query 626 HYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRES 685
+++ C CH SC C+GP +C C + L + C R +S
Sbjct 1622 NFN------------CKKCHESCMECKGPGSKNCTGCSAGLLLQMDDSRCLRCCNASHPH 1669
Query 686 PPQ 688
Q
Sbjct 1670 RSQ 1672
Score = 52.5 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 23/105 (22%), Positives = 32/105 (30%), Gaps = 25/105 (24%)
Query 582 PESSGCKTLTSSQA---------CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEND 632
E C+ +S A C+ C CV +CP
Sbjct 882 DEQGHCQICDASCAKCWGPTQDDCISCPITRVFDDGRCVMNCP----------------S 925
Query 633 VETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSR 677
+ C PCH +C CQG ++C SC + D C
Sbjct 926 WKFELKKQCHPCHHTCQGCQGSGPSNCTSCKAGEFQDSEYGECMP 970
Score = 51.7 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 34/139 (24%), Positives = 44/139 (32%), Gaps = 23/139 (17%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
S CKT T C C+ G SL C C G D C P
Sbjct 743 SENCKTCTGFHNCTECKGGLSLQGSRCSVTCEDGQFFSGHD----------------CQP 786
Query 644 CHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQR 703
CH CATC G C++C ++ E C + S L ++ +R
Sbjct 787 CHRFCATCAGAGADGCINCTEGYVME--EGRCVQSC-----SVSYYLDHSLEGGYKSCKR 839
Query 704 LRAGLLPSHLPEVVAGLSC 722
L + P SC
Sbjct 840 CDNSCLTCNGPGFKNCSSC 858
Score = 51.0 bits (120), Expect = 5e-05, Method: Composition-based stats.
Identities = 32/102 (31%), Positives = 39/102 (38%), Gaps = 17/102 (17%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVC 641
P S CKT S C C G L ++CV CP G ++R+S C
Sbjct 1142 PCHSSCKTCNGS-LCTSCPAGTYLWLQACVPSCPQG--------------TWLSVRSSSC 1186
Query 642 APCHASCATCQGPALTD-CLSCPSHASLDPVEQTCSRQSQSS 682
C CA+C G L CLS PS+ L E C
Sbjct 1187 EKCAEGCASCSGDDLCQRCLSQPSNTLL-LHEGRCYHSCPEG 1227
Score = 46.7 bits (109), Expect = 0.001, Method: Composition-based stats.
Identities = 26/103 (25%), Positives = 32/103 (31%), Gaps = 23/103 (22%)
Query 585 SGCKTLTSSQACVVC----EEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASV 640
GC + + C C LH+ C CP GF + V
Sbjct 1191 EGCASCSGDDLCQRCLSQPSNTLLLHEGRCYHSCPEGFYA----------------KDGV 1234
Query 641 CAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
C C + C TC+G A T C SC LD C
Sbjct 1235 CEHCSSPCKTCKGNA-TSCHSCEGDFVLD--HGVCWETCPEKH 1274
>sp|P29120|NEC1_HUMAN Neuroendocrine convertase 1 OS=Homo sapiens
OX=9606 GN=PCSK1 PE=1 SV=2
Length=753
Score = 822 bits (2124), Expect = 0.0, Method: Composition-based stats.
Identities = 330/757 (44%), Positives = 444/757 (59%), Gaps = 52/757 (7%)
Query 1 MELRPWLLWVVAATGTLVLLAAD-AQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQ 59
ME R W L A A + A+ ++ F N WA IPGGP A+++A + G+ LGQ
Sbjct 1 MERRAWSLQCTAFVLFCAWCALNSAKAKRQFVNEWAAEIPGGPEAASAIAEELGYDLLGQ 60
Query 60 I--FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP---- 113
I ++Y F H+ +RS RL + +V W EQQ K R+KR ++
Sbjct 61 IGSLENHYLFKHKNHPRRSRRSAFHITKRLSDDDRVIWAEQQYEKERSKRSALRDSALNL 120
Query 114 -TDPKFPQQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
DP + QQWYL + + + DL+V W +G TG G+V+++LDDG+E NH D+ N
Sbjct 121 FNDPMWNQQWYLQDTRMTAALPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYAN 180
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
YDP AS+D ND D DP PRY N+N+HGTRCAGE+A ANN CGVGVAYN+++GG+RM
Sbjct 181 YDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM 240
Query 227 LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLG 286
LDG VTDA+EA S+G NP H+ IYSASWGP DDGKTV+GP RLA++AF GV QGR G G
Sbjct 241 LDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG 300
Query 287 SIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ 346
SIFVWASGNGGR+ D+C+CDGYT+SIYT+SISSA+Q G PWY+E CSSTLAT+YSSG+
Sbjct 301 SIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY 360
Query 347 NEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
+++I + DL CTE+HTGTSASAPLAAGI AL LEAN NLTWRDMQHLVV TS+ L
Sbjct 361 TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL 420
Query 407 -NANDWATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCII-DILTEPKDIG 462
N W NG G V+ +G+GLL+A A+V LA + W +V +++C++ D EP+ +
Sbjct 421 ANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRSVPEKKECVVKDNDFEPRALK 480
Query 463 KRLEV--RKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARP 520
EV AC G+ N I LEH Q T+ Y+RRGDL + L S GT + LLA R
Sbjct 481 ANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERE 540
Query 521 HDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS-EANNYGTLTKFTLVLYGTA--PEG 577
D S +GF +W FM+ H+W E+P G W L I + S N G + + L+L+GT+ PE
Sbjct 541 RDTSPNGFKNWDFMSVHTWGENPIGTWTLRITDMSGRIQNEGRIVNWKLILHGTSSQPEH 600
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
+ P + T+ + + V E+ ++ Q P +
Sbjct 601 MKQPRVYTSYNTVQNDRRGV--EKMVDPGEEQPTQENP---------------------K 637
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS---QSSRESPPQQQPPRL 694
+ S ++ G PS A L ++ S+ S QS ++SP +
Sbjct 638 ENTLVSKSPSSSSVGGRRDELEEGAPSQAMLRLLQSAFSKNSPPKQSPKKSPSAKLNIPY 697
Query 695 PPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVT 731
EA ++L PS L + L ++ + + T
Sbjct 698 ENFYEALEKLNK---PSQLKDSEDSLYNDYVDVFYNT 731
>sp|Q92824|PCSK5_HUMAN Proprotein convertase subtilisin/kexin
type 5 OS=Homo sapiens OX=9606 GN=PCSK5 PE=1 SV=4
Length=1860
Score = 816 bits (2107), Expect = 0.0, Method: Composition-based stats.
Identities = 354/730 (48%), Positives = 439/730 (60%), Gaps = 73/730 (10%)
Query 15 GTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--FGDYYHFWHRGV 72
G +L +V+TN WAV+I GG AN +A K+GF+N+GQI DYYHF+H
Sbjct 23 GGCLLPVCRT---RVYTNHWAVKIAGGFPEANRIASKYGFINIGQIGALKDYYHFYHSRT 79
Query 73 TKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQE------PTDPKFPQQWYLS- 125
KRS+ R HS + EP+V+W++QQV K+RTKRD DPK+P WY+
Sbjct 80 IKRSVISSRGTHSFISMEPKVEWIQQQVVKKRTKRDYDFSRAQSTYFNDPKWPSMWYMHC 139
Query 126 ----GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
Q D+N++ AW +GYTG IVV+ILDDGIE+ HPDL NYD AS DVN D D
Sbjct 140 SDNTHPCQSDMNIEGAWKRGYTGKNIVVTILDDGIERTHPDLMQNYDALASCDVNGNDLD 199
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLG 241
P PRY N+N+HGTRCAGEVAA ANN C VG+A+NA+IGGVRMLDG+VTD VEA+S+
Sbjct 200 PMPRYDASNENKHGTRCAGEVAAAANNSHCTVGIAFNAKIGGVRMLDGDVTDMVEAKSVS 259
Query 242 LNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHD 301
NP H+HIYSASWGP+DDGKTVDGPA L +AF GV GR GLGS+FVWASGNGGR D
Sbjct 260 FNPQHVHIYSASWGPDDDGKTVDGPAPLTRQAFENGVRMGRRGLGSVFVWASGNGGRSKD 319
Query 302 SCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCT 361
C+CDGYTNSIYT+SISS + G PWY E CSSTLATTYSSG +K+I+TTDLRQ+CT
Sbjct 320 HCSCDGYTNSIYTISISSTAESGKKPWYLEECSSTLATTYSSGESYDKKIITTDLRQRCT 379
Query 362 ESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVS 421
++HTGTSASAP+AAGIIAL LEAN LTWRD+QH++V+TS+ HLNANDW TN G KVS
Sbjct 380 DNHTGTSASAPMAAGIIALALEANPFLTWRDVQHVIVRTSRAGHLNANDWKTNAAGFKVS 439
Query 422 HSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRK--TVTACLGEPN 479
H YG+GL+DA AMV A+ WTTV Q C+ + K I VR + C PN
Sbjct 440 HLYGFGLMDAEAMVMEAEKWTTVPRQHVCVESTDRQIKTIRPNSAVRSIYKASGCSDNPN 499
Query 480 -HITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHS 538
H+ LEH R+T+++ RRGDLAI+L SP GTRS LLA R D+S +GF +W FMT H
Sbjct 500 RHVNYLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHC 559
Query 539 WDEDPSGEWVLEIENTSEA----NNYGTLTKFTLVLYGTAPEGL---------------- 578
W E +G+WVLE+ +T G L +++LVLYGT+ +
Sbjct 560 WGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERFRYSR 619
Query 579 ---------------PVPPESS--GCKTLTSSQACVVCEEGFSLHQKS--CVQHCPPGFA 619
P PE S GC + L + CV CPPG
Sbjct 620 VEDPTDDYGTEDYAGPCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPG-- 677
Query 620 PQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS 679
HY + C C +C +C G C+SC L+ +C
Sbjct 678 ------HYHADKK-------RCRKCAPNCESCFGSHGDQCMSCKYGYFLNEETNSCVTHC 724
Query 680 QSSRESPPQQ 689
++
Sbjct 725 PDGSYQDTKK 734
Score = 68.3 bits (165), Expect = 3e-10, Method: Composition-based stats.
Identities = 36/122 (30%), Positives = 44/122 (36%), Gaps = 24/122 (20%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQA------CVVCEEGFSLHQKSCVQHCPPGFAPQVLD 624
Y T PE E CK S+ C CEEGF L SCV+ C PGF
Sbjct 1068 YKTCPE--KTYSEEVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEM 1125
Query 625 THYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRE 684
C CH +C TC GP +C SC L + C +++ E
Sbjct 1126 GE--------------CESCHRACETCTGPGHDECSSC--QEGLQLLRGMCVHATKTQEE 1169
Query 685 SP 686
Sbjct 1170 GK 1171
Score = 65.6 bits (158), Expect = 2e-09, Method: Composition-based stats.
Identities = 32/150 (21%), Positives = 45/150 (30%), Gaps = 26/150 (17%)
Query 574 APEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDV 633
AP P + C Q C C L +CV+ CP G+
Sbjct 1465 APGCKPCHVKCFHCMGPAEDQ-CQTCPMNSLLLNTTCVKDCPEGYYADED---------- 1513
Query 634 ETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPR 693
++ CA CH+SC TC+G C SC + + C Q + +
Sbjct 1514 ----SNRCAHCHSSCRTCEGRHSRQCHSCRPGWF--QLGKECLLQCREGYYADNSTGRC- 1566
Query 694 LPPEVEAGQRLRAGLLPSHLPEVVAGLSCA 723
+R P LSC
Sbjct 1567 --------ERCNRSCKGCQGPRPTDCLSCD 1588
Score = 62.9 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 24/107 (22%), Positives = 39/107 (36%), Gaps = 13/107 (12%)
Query 576 EGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVET 635
E C T +SS C C++G ++ + + + ++
Sbjct 1414 ETKECRDCHKSCLTCSSSGTCTTCQKGLIMNPR-----------GSCMANEKCSPSEYWD 1462
Query 636 IRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
A C PCH C C GPA C +CP ++ L + TC +
Sbjct 1463 EDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLL--LNTTCVKDCPEG 1507
Score = 60.2 bits (144), Expect = 8e-08, Method: Composition-based stats.
Identities = 31/96 (32%), Positives = 41/96 (43%), Gaps = 12/96 (13%)
Query 577 GLPVPPESSGCKTLTSSQA--CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
G P C T + A C+ C EG+ + CVQ C + +S+EN +
Sbjct 779 GQDCQPCHRFCATCAGAGADGCINCTEGYFMEDGRCVQSCSISYYFD-----HSSENGYK 833
Query 635 TIRASVCAPCHASCATCQGPALTDCLSCPSHASLDP 670
+ C C SC TC GP +C SCPS LD
Sbjct 834 S-----CKKCDISCLTCNGPGFKNCTSCPSGYLLDL 864
Score = 59.4 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 32/142 (23%), Positives = 43/142 (30%), Gaps = 33/142 (23%)
Query 572 GTAPEGLPVPPESSGCKTLT-SSQACVVCEEGFSLHQKSCVQHCP--------------- 615
G+ E SS C+T ++ C CE G LH C ++CP
Sbjct 1269 GSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVKGVCKHCPE 1328
Query 616 ---------------PGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCL 660
P F H S + C PCH C C GP DC
Sbjct 1329 MCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYA-DSRHCVPCHKDCLECSGPKADDCE 1387
Query 661 SCPSHASLDPVEQTCSRQSQSS 682
C +S + C + +
Sbjct 1388 LC-LESSWVLYDGLCLEECPAG 1408
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 31/116 (27%), Positives = 38/116 (33%), Gaps = 23/116 (20%)
Query 575 PEGLPVPPESSGCKTLTSSQA---------CVVCEEGFSLHQKSCVQHCPPGFAPQVLDT 625
PEG +S+ C SS C C G+ K C+ C G+
Sbjct 1505 PEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTG 1564
Query 626 HYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
C C+ SC CQGP TDCLSC L + C R
Sbjct 1565 --------------RCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPD 1606
Score = 54.4 bits (129), Expect = 4e-06, Method: Composition-based stats.
Identities = 32/181 (18%), Positives = 55/181 (30%), Gaps = 22/181 (12%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQ---------ACVVCEEGFSLHQKSCVQHCPPGFAPQ 621
+ + P+ V + C+ + C+ C + L C C G
Sbjct 1601 HRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRV 1660
Query 622 VLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
++ C CH SC C+GP +C CP++ L + C +
Sbjct 1661 GEGEKFN------------CEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCNT 1708
Query 682 SRESPPQQQPPRLPPEVEAGQRLRAGLLPS-HLPEVVAGLSCAFIVLVFVTVFLVLQLRS 740
S Q+ E R + H + S +VL+ +V +
Sbjct 1709 SDPPSAQECCDCQDTTDECILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSR 1768
Query 741 G 741
G
Sbjct 1769 G 1769
Score = 54.1 bits (128), Expect = 6e-06, Method: Composition-based stats.
Identities = 26/130 (20%), Positives = 34/130 (26%), Gaps = 28/130 (22%)
Query 582 PESSGCKTLTSSQA---------CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEND 632
E C+T +S A C C CV +CP
Sbjct 880 DEHGHCQTCEASCAKCQGPTQEDCTTCPMTRIFDDGRCVSNCP----------------S 923
Query 633 VETIRASVCAPCHASCATCQGPALTDCLSC---PSHASLDPVEQTCSRQSQSSRESPPQQ 689
+ + C PCH +C CQG T C SC + C +
Sbjct 924 WKFEFENQCHPCHHTCQRCQGSGPTHCTSCGADNYGREHFLYQGECGDSCPEGHYATEGN 983
Query 690 QPPRLPPEVE 699
P E
Sbjct 984 TCLPCPDNCE 993
Score = 53.3 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 27/99 (27%), Positives = 34/99 (34%), Gaps = 18/99 (18%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
S CKT T C C +G SL C C G D C P
Sbjct 741 SENCKTCTEFHNCTECRDGLSLQGSRCSVSCEDGRYFNGQD----------------CQP 784
Query 644 CHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
CH CATC G C++C ++ + C + S
Sbjct 785 CHRFCATCAGAGADGCINCTEGYFME--DGRCVQSCSIS 821
Score = 51.4 bits (121), Expect = 4e-05, Method: Composition-based stats.
Identities = 29/107 (27%), Positives = 39/107 (36%), Gaps = 17/107 (16%)
Query 578 LPVPPESSGCKTLT-SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETI 636
+ P S CKT S+ C C +G L ++CV CP G ++
Sbjct 1178 RKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQG--------------TWPSV 1223
Query 637 RASVCAPCHASCATCQGPAL-TDCLSCPSHASLDPVEQTCSRQSQSS 682
R+ C C +CA C G L C P H L E C +
Sbjct 1224 RSGSCENCTEACAICSGADLCKKCQMQPGHP-LFLHEGRCYSKCPEG 1269
Score = 46.7 bits (109), Expect = 0.001, Method: Composition-based stats.
Identities = 26/118 (22%), Positives = 36/118 (31%), Gaps = 25/118 (21%)
Query 572 GTAPEGLPVPPE--SSGCKTLTSSQACVVCE----EGFSLHQKSCVQHCPPGFAPQVLDT 625
GT P E + C + + C C+ LH+ C CP G +
Sbjct 1218 GTWPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAED--- 1274
Query 626 HYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
+C C + C TC+G A T+C SC L C
Sbjct 1275 -------------GICERCSSPCRTCEGNA-TNCHSCEGGHVLH--HGVCQENCPERH 1316
Score = 44.4 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 20/113 (18%), Positives = 29/113 (26%), Gaps = 13/113 (12%)
Query 574 APEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDV 633
A EG P C+ S C C +G+ + + +V
Sbjct 979 ATEGNTCLPCPDNCELCHSVHVCTRCMKGYFIAP-----------TNHTCQKLECGQGEV 1027
Query 634 ETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESP 686
+ C PC C C C SC + C + S
Sbjct 1028 QDPDYEECVPCEEGCLGCSLDDPGTCTSC--AMGYYRFDHHCYKTCPEKTYSE 1078
Score = 40.2 bits (92), Expect = 0.095, Method: Composition-based stats.
Identities = 25/123 (20%), Positives = 36/123 (29%), Gaps = 21/123 (17%)
Query 579 PVPPESSGCKTLTSSQACVVCEEGF----SLHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
P C+ + + + L+Q C CP G HY+TE
Sbjct 934 PCHHTCQRCQGSGPTHCTSCGADNYGREHFLYQGECGDSCPEG--------HYATEG--- 982
Query 635 TIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRL 694
+ C PC +C C C C + P TC + E +
Sbjct 983 ----NTCLPCPDNCELCHSVH--VCTRCMKGYFIAPTNHTCQKLECGQGEVQDPDYEECV 1036
Query 695 PPE 697
P E
Sbjct 1037 PCE 1039
>sp|Q9GLR1|NEC1_BOVIN Neuroendocrine convertase 1 OS=Bos taurus
OX=9913 GN=PCSK1 PE=2 SV=1
Length=753
Score = 804 bits (2077), Expect = 0.0, Method: Composition-based stats.
Identities = 330/757 (44%), Positives = 441/757 (58%), Gaps = 52/757 (7%)
Query 1 MELRPWLLWVVAATGTLVLLAADA-QGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQ 59
M R W L A + A ++ + +K F N WA IPGGP A+++A++ G+ LGQ
Sbjct 1 MGRRAWTLQCTAFSLFCAWCAMNSVKAKKQFVNEWAAEIPGGPEAASAIAQELGYDLLGQ 60
Query 60 I--FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEP---- 113
I ++Y F HR +RS RL + +V W EQQ K R+KR V ++
Sbjct 61 IGSLENHYLFKHRNHPRRSRRSALHITKRLSDDDRVIWAEQQYEKERSKRSVLRDSALDL 120
Query 114 -TDPKFPQQWYLSGV------TQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
DP + QQWYL + DL+V W +G TG G+V+++LDDG+E NH D+ N
Sbjct 121 FNDPMWNQQWYLQDTRMTATLPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYAN 180
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
YDP AS+D ND D DP PRY +N+N+HGTRCAGE+A ANN CGVGVAYN+++GG+RM
Sbjct 181 YDPEASYDFNDNDHDPFPRYDLINENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM 240
Query 227 LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLG 286
LDG VTDA+EA +G NP H+ IYSASWGP DDGKTV+GP RLA++AF GV QGR G G
Sbjct 241 LDGIVTDAIEASLIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG 300
Query 287 SIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ 346
SIFVWASGNGGR+ D+C+CDGYT+SIYT+SI+SA+Q G PWY+E CSSTLAT+YSSG+
Sbjct 301 SIFVWASGNGGRQGDNCDCDGYTDSIYTISINSASQQGLSPWYAEKCSSTLATSYSSGDY 360
Query 347 NEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
+++I + DL CTE+HTGTSASAPLAAGI AL LEAN NLTWRDMQHLVV TS+ L
Sbjct 361 TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL 420
Query 407 -NANDWATNGVGRKVSHSYGYGLLDAGAMVALA--QNWTTVAPQRKCII-DILTEPKDIG 462
N W NG G V+ +G+GLL+A A+V LA W++V +++C++ D EP+ +
Sbjct 421 ANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPSTWSSVPEKKECVVKDNDFEPRALK 480
Query 463 KRLEV--RKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARP 520
EV AC G+ N I LEH Q T+ Y+RRGDL + L S GT + LLA R
Sbjct 481 ANGEVIIEIPTRACEGQENAIKSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERE 540
Query 521 HDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS-EANNYGTLTKFTLVLYGTA--PEG 577
D S +GF +W FM+ H+W E+P G W L I + S N G + + L+L+GT+ PE
Sbjct 541 RDTSPNGFKNWDFMSVHTWGENPIGTWTLRIADMSGRIQNEGRIVTWKLILHGTSSQPEH 600
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
+ P + T+ + + V E+ ++ Q EN +
Sbjct 601 MKQPRVYTSYNTVQNDRRGV--EKVVDSGEEQPTQE-------------GLDENAQASQ- 644
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS---QSSRESPPQQQPPRL 694
S + G PS A L ++ S+ S QS ++ P +
Sbjct 645 -------SPSGSGVGGRRDELAEGAPSEAMLRLLQSAFSKNSPSKQSPKKPPSAKPNIPY 697
Query 695 PPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVT 731
EA +RL PS L + L ++ + T
Sbjct 698 ENFYEALERLNK---PSQLKDSEDSLYNDYVDGFYNT 731
>sp|Q78EH2|PCSK4_RAT Proprotein convertase subtilisin/kexin type
4 OS=Rattus norvegicus OX=10116 GN=Pcsk4 PE=2 SV=1
Length=678
Score = 775 bits (2001), Expect = 0.0, Method: Composition-based stats.
Identities = 348/583 (60%), Positives = 425/583 (73%), Gaps = 7/583 (1%)
Query 27 QKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGD--YYHFWHRGVTKRSLSPHRPRH 84
++ ++WAVR+ G A +ARK GF+NLGQIF D Y+H HRGV ++SL+PH
Sbjct 28 PPIYVSSWAVRVTKGYQEAERLARKFGFVNLGQIFPDDQYFHLRHRGVAQQSLTPHWGHR 87
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
RL++EP+V+W EQQ +RR KR + PTDP F +QWY++ ++DLN+ W QG TG
Sbjct 88 LRLKKEPKVRWFEQQTLRRRVKRSLVV-PTDPWFSKQWYMNKEIEQDLNILKVWNQGLTG 146
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G+VVSILDDGIEK+HPDL NYDP AS+D ND DPDPQPRYT ++NRHGTRCAGEV+A
Sbjct 147 RGVVVSILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSA 206
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVD 264
ANNG CG GVA+NARIGGVRMLDG +TD VEA+SL L P HIHIYSASWGPEDDG+TVD
Sbjct 207 TANNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVD 266
Query 265 GPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFG 324
GP L +EAF RGV++GR GLG++F+WASGNGG +D+CNCDGYTNSI+TLS+ S T+ G
Sbjct 267 GPGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQG 326
Query 325 NVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA 384
VPWYSEAC+ST TT+SSG + QIVTTDL +CT+ HTGTSASAPLAAG+IAL LEA
Sbjct 327 RVPWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEA 386
Query 385 NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTV 444
N LTWRD+QHLVV+ S+PA L A DW NGVGR+VSH YGYGLLDAG +V LA+ W
Sbjct 387 NPLLTWRDLQHLVVRASRPAQLQAEDWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPT 446
Query 445 APQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH--ITRLEHAQARLTLSYNRRGDLA 502
PQ+KC I ++ P I R+ V K VT C I LEH Q +L+LSY+RRGDL
Sbjct 447 KPQKKCTIRVVHTPTPILPRMLVPKNVTVCCDGSRRRLIRSLEHVQVQLSLSYSRRGDLE 506
Query 503 IHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGT 562
I L SPMGTRSTL+A RP D S G+N+W FM+TH WDEDP G W L +EN N GT
Sbjct 507 IFLTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLENKGYYYNTGT 566
Query 563 LTKFTLVLYGTAPE--GLPVPPESSGCKTLTSSQACVVCEEGF 603
L TL+LYGTA + P P+ S C ++ C++ + +
Sbjct 567 LYYCTLLLYGTAEDMTARPQTPQESHCPLSIVAELCLISSKQW 609
>sp|Q9NJ15|PCSK5_BRACL Proprotein convertase subtilisin/kexin
type 5 OS=Branchiostoma californiense OX=7738 GN=PC6 PE=2 SV=1
Length=1696
Score = 765 bits (1974), Expect = 0.0, Method: Composition-based stats.
Identities = 359/777 (46%), Positives = 447/777 (58%), Gaps = 115/777 (15%)
Query 7 LLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--FGDY 64
L AA + L A G +++ N WA+ + GG A A+ +A KHGF+N GQI D+
Sbjct 8 LALFTAALCAVNLRTVAADGPRIYRNEWALHVEGGTAAADRLASKHGFINKGQIGSLEDH 67
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWL----------------------EQQVAK 102
Y F HR KRSL RH+ LQREP+V+WL EQ+V
Sbjct 68 YLFVHRRTWKRSLRSSSHRHALLQREPEVRWLQQQVVKRRVKRRVKRVYSMYPWEQRVQH 127
Query 103 ------RRTKRDVYQEP--TDPKFPQQWYLS------GVTQRDLNVKAAWAQGYTGHGIV 148
++D +P D K+ + WYL D+NV+AAW +GYTG G+V
Sbjct 128 SSPQVNNPAQQDNLWDPHFNDEKWDKMWYLHCDRPEFACQWSDMNVEAAWKKGYTGKGVV 187
Query 149 VSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANN 208
VSILDDG E +HPDLAGNYDP AS D+N DP PRY N+NRHGTRCAGEVAA+ NN
Sbjct 188 VSILDDGSETDHPDLAGNYDPDASSDINGGTLDPTPRYEYTNENRHGTRCAGEVAAMGNN 247
Query 209 GVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPAR 268
C VGVAY A IGGVRMLDG+VTD+VEA SLGLNP HI IYSASWGP+DDGKTVDGPA
Sbjct 248 SFCSVGVAYKASIGGVRMLDGDVTDSVEAASLGLNPQHIMIYSASWGPDDDGKTVDGPAN 307
Query 269 LAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPW 328
LA++ F G GR LGSIFVWASGNGGR HDSC CDGYTNSIYT+S+SSA++ G VPW
Sbjct 308 LAQKTFQAGAENGRDKLGSIFVWASGNGGRTHDSCGCDGYTNSIYTISVSSASEQGKVPW 367
Query 329 YSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNL 388
Y E C+STLATTYSSG +E++++TTDLR+ CTESHTGTSASAP+AAGI+AL LEAN L
Sbjct 368 YLEPCASTLATTYSSGAPHERKVITTDLRKGCTESHTGTSASAPMAAGILALALEANPML 427
Query 389 TWRDMQHLVVQTSKPAHLNAN-------------DWATNGVGRKVSHSYGYGLLDAGAMV 435
TWRDMQ++VV + P+ L+ + D+ TNG G +VSH++G+GL+DAG MV
Sbjct 428 TWRDMQYIVVMAANPSPLDRDTESAYPRDPRKESDFVTNGAGLRVSHNFGFGLMDAGKMV 487
Query 436 ALAQNWTTVAPQRKCIIDILTEPKDI--GKRLEVRKTVTACLGEPNHITRLEHAQARLTL 493
LA++W V Q C D + + I G+ + KT C G +H+ LEH ++L
Sbjct 488 ELAESWRRVPEQHVCEEDPNAQQRAITKGETIVDTKTTGGCNGTDHHVKYLEHVVVEISL 547
Query 494 SYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIEN 553
+ RG L+IH+ SP GTRSTLL R D S+DG DWAFMTTH W E P G+W+LE+++
Sbjct 548 DHPCRGHLSIHITSPSGTRSTLLPERQFDSSSDGLKDWAFMTTHCWGEQPEGDWILEVKD 607
Query 554 TSEAN--NYG------TLTKFTLVLYGTA--------PEGLPVPPESSG----------- 586
+ N YG L K+ L+LYGTA E P P++
Sbjct 608 LGQQNCQRYGLRTVLPVLRKWKLILYGTAEHPLYKRDEESRPHTPQTREEPTDEEECEDG 667
Query 587 ---------CKTLTSSQA---------CVVCEEG--FSLHQKSCVQHCPPGFAPQVLDTH 626
C+ S A C+ C EG F + +C + C G+ +
Sbjct 668 DYYDRSKQRCRHCHDSCATCHGRHSGQCLSCHEGNYFVEDEGTCSEECGQGYYKDEEE-- 725
Query 627 YSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
C C A C TCQ A C SC L E TC Q R
Sbjct 726 ------------RKCLDCSADCLTCQVSAD-HCTSCDDEDGLKLFENTCVAQCSEGR 769
Score = 67.5 bits (163), Expect = 4e-10, Method: Composition-based stats.
Identities = 29/107 (27%), Positives = 37/107 (35%), Gaps = 17/107 (16%)
Query 576 EGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVET 635
E P C ++Q C C+EGF C CP + +
Sbjct 1065 ECRPCHDNCEACDGP-NNQNCNSCKEGFYKTPDGCSTGCPNRYYKDDTNKE--------- 1114
Query 636 IRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C PC +SC TC GPA CLSC L E +C +
Sbjct 1115 -----CKPCDSSCFTCSGPASFHCLSCADGDFLH--ESSCRSTCPAG 1154
Score = 63.7 bits (153), Expect = 6e-09, Method: Composition-based stats.
Identities = 25/109 (23%), Positives = 39/109 (36%), Gaps = 10/109 (9%)
Query 577 GLPVPPESSGCKTLTSSQ--ACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
CKT C+ C+ G L+ + C HCP G + Y ++
Sbjct 1330 HGDCDSCHRECKTCDGPHHDNCLSCQPGSYLNDQQCSTHCPEGTFEET----YEDDSGET 1385
Query 635 TIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
+ C CH +C TC G DC+ C ++ + C + Q
Sbjct 1386 VL---QCRLCHVNCKTCHGEGEEDCMEC-ANDIKYKQDGRCVTECQEGH 1430
Score = 62.9 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 25/106 (24%), Positives = 35/106 (33%), Gaps = 17/106 (16%)
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIR 637
C + CV C + L + CV+ C G+ Q +
Sbjct 778 QDCDDSCDTCTGPD-ATDCVTCADEDLLQESQCVESCSSGYFQQEYE------------- 823
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
C CHA+CA+C G CL+C H LD C +
Sbjct 824 ---CLKCHATCASCSGSRDDQCLTCSGHLELDEDTHRCITSCEDGE 866
Score = 61.0 bits (146), Expect = 4e-08, Method: Composition-based stats.
Identities = 30/112 (27%), Positives = 36/112 (32%), Gaps = 28/112 (25%)
Query 581 PPESSGCKTLTSSQ---------ACVVCEEGFSLHQKS-CVQHCPPGFAPQVLDTHYSTE 630
CK + C C +GF L S C CPPG D
Sbjct 1279 DRREKKCKACHPTCKECSDEYDDTCTACNDGFLLTDASSCEAGCPPGQFLHHGD------ 1332
Query 631 NDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C CH C TC GP +CLSC + L+ +Q CS
Sbjct 1333 ----------CDSCHRECKTCDGPHHDNCLSCQPGSYLN--DQQCSTHCPEG 1372
Score = 60.2 bits (144), Expect = 7e-08, Method: Composition-based stats.
Identities = 26/100 (26%), Positives = 37/100 (37%), Gaps = 16/100 (16%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVC 641
+ C + Q CV C + L C++ CP G+ + + C
Sbjct 1443 SDCETCDGPRNDQ-CVTCPYNYYLVLGKCLEDCPEGYYDTMR-------------QEKEC 1488
Query 642 APCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
CH SCATC +CLSCP + L E C +
Sbjct 1489 GECHPSCATCNEGGNYNCLSCPYGSKLG--EGVCYPMCEE 1526
Score = 59.4 bits (142), Expect = 1e-07, Method: Composition-based stats.
Identities = 22/93 (24%), Positives = 31/93 (33%), Gaps = 9/93 (10%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C+ + C C + + C D Y + + C PCH
Sbjct 1189 CRACDNDGDCAECAPTYIVVDGRC------RPEETCEDGEYQDRDRDTAELS--CRPCHQ 1240
Query 647 SCATCQGPALTDCLSCPSHASLDPVEQTCSRQS 679
SC TC GP+ TDC SC ++ C
Sbjct 1241 SCKTCSGPSDTDCDSCKGDDTI-LDRGECITSC 1272
Score = 53.3 bits (126), Expect = 9e-06, Method: Composition-based stats.
Identities = 26/100 (26%), Positives = 36/100 (36%), Gaps = 19/100 (19%)
Query 585 SGCKTLTSSQ-ACVVCEEGFSLHQKSCVQ--HCPPGFAPQVLDTHYSTENDVETIRASVC 641
GC + C C+E + L + +CV+ +CP P D C
Sbjct 1021 EGCHSCEEGPDICDSCDEDYYLTEDTCVRRTNCPSFTYPDDQD--------------REC 1066
Query 642 APCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
PCH +C C GP +C SC P CS +
Sbjct 1067 RPCHDNCEACDGPNNQNCNSCKEGFYKTP--DGCSTGCPN 1104
Score = 52.1 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 28/115 (24%), Positives = 36/115 (31%), Gaps = 20/115 (17%)
Query 576 EGLPVPPESSGCKTLTSSQACVVCE----EGFSLHQKSCVQHCPPGFAPQVLDTHYSTEN 631
E P P GC +Q E L+Q +C CPPG D
Sbjct 920 ECHPCHPSCLGCIGGEINQCNQCITDYEGEDHFLYQGTCHVTCPPGLYGDTTD------- 972
Query 632 DVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESP 686
VC C C C GPA C C + P + C + + E+
Sbjct 973 -------QVCKACAPGCIACDGPADNQCTLCEEERA--PTDGRCQSEGSQTDEAE 1018
Score = 52.1 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 25/116 (22%), Positives = 38/116 (33%), Gaps = 21/116 (18%)
Query 571 YGTAP-EGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
YGT + C + Q C+ C +L+ +CVQ+C P+ + H
Sbjct 867 YGTEEGKCEDCNIICKKCNGSQADQ-CLECHHDTNLYDTTCVQYCGNRRYPENGECH--- 922
Query 630 ENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLD---PVEQTCSRQSQSS 682
PCH SC C G + C C + + + TC
Sbjct 923 -------------PCHPSCLGCIGGEINQCNQCITDYEGEDHFLYQGTCHVTCPPG 965
Score = 49.8 bits (117), Expect = 1e-04, Method: Composition-based stats.
Identities = 27/130 (21%), Positives = 39/130 (30%), Gaps = 22/130 (17%)
Query 573 TAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQ------HCPPGFAPQVLDTH 626
T P+ + L SQ C G+ + C++ C Q L
Sbjct 788 TGPDATDC-VTCADEDLLQESQCVESCSSGYFQQEYECLKCHATCASCSGSRDDQCLTCS 846
Query 627 YSTENDVETIRA-------------SVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQ 673
E D +T R C C+ C C G CL C H + +
Sbjct 847 GHLELDEDTHRCITSCEDGEYGTEEGKCEDCNIICKKCNGSQADQCLEC--HHDTNLYDT 904
Query 674 TCSRQSQSSR 683
TC + + R
Sbjct 905 TCVQYCGNRR 914
Score = 48.3 bits (113), Expect = 4e-04, Method: Composition-based stats.
Identities = 23/109 (21%), Positives = 33/109 (30%), Gaps = 18/109 (17%)
Query 578 LPVPPESSGCKTLT--SSQACVVCEEGFS-LHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
L P CKT + S C C+ + L + C+ C PG +
Sbjct 1233 LSCRPCHQSCKTCSGPSDTDCDSCKGDDTILDRGECITSCGPG--------------EYM 1278
Query 635 TIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
R C CH +C C C +C L +C +
Sbjct 1279 DRREKKCKACHPTCKECSDEYDDTCTACNDGFLLTDA-SSCEAGCPPGQ 1326
>sp|P26016|FUR11_DROME Furin-like protease 1, isoforms 1/1-X/2
OS=Drosophila melanogaster OX=7227 GN=Fur1 PE=2 SV=2
Length=1269
Score = 756 bits (1951), Expect = 0.0, Method: Composition-based stats.
Identities = 340/665 (51%), Positives = 421/665 (63%), Gaps = 32/665 (5%)
Query 30 FTNTWAVRIPGG-PAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQ 88
+T+TWAV IP G +A++VA+ HGF+NLG+IF D+YHF H V+KRSLSP +RL
Sbjct 231 YTHTWAVHIPNGDNGMADAVAKDHGFVNLGKIFDDHYHFAHHKVSKRSLSPATHHQTRLD 290
Query 89 REPQVQWLEQQVAKRRTKRDVYQ-----------------EPTDPKFPQQWYLSGVTQRD 131
+ +V W +QQ AK R+KRD + D K+PQ WYL+ D
Sbjct 291 DDDRVHWAKQQRAKSRSKRDFIRMRPSRTSSRAMSMVDAMSFNDSKWPQMWYLNRGGGLD 350
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND 191
+NV AW G TG G+VV+ILDDG+E +HPD+ NYDP AS+DVN D DP P Y +
Sbjct 351 MNVIPAWKMGITGKGVVVTILDDGLESDHPDIQDNYDPKASYDVNSHDDDPMPHYDMTDS 410
Query 192 NRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS 251
NRHGTRCAGEVAA ANN C VG+AY A +GGVRMLDG+VTDAVEARSL LNP HI IYS
Sbjct 411 NRHGTRCAGEVAATANNSFCAVGIAYGASVGGVRMLDGDVTDAVEARSLSLNPQHIDIYS 470
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
ASWGP+DDGKTVDGP LA AF G ++GRGG GSIF+WASGNGGRE D+CNCDGYTNS
Sbjct 471 ASWGPDDDGKTVDGPGELASRAFIEGTTKGRGGKGSIFIWASGNGGREQDNCNCDGYTNS 530
Query 312 IYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASA 371
I+TLSISSAT+ G+VPWYSE CSSTLATTYSSG Q EKQ+VTTDL CT SHTGTSASA
Sbjct 531 IWTLSISSATEEGHVPWYSEKCSSTLATTYSSGGQGEKQVVTTDLHHSCTVSHTGTSASA 590
Query 372 PLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDA 431
PLAAGI AL L++N+NLTWRD+QH+VV+T+KPA+L W+ NGVGR+VSHS+GYGL+DA
Sbjct 591 PLAAGIAALVLQSNQNLTWRDLQHIVVRTAKPANLKDPSWSRNGVGRRVSHSFGYGLMDA 650
Query 432 GAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARL 491
MV +A+NW V Q++C I+ K I R + +T + + LEH QA++
Sbjct 651 AEMVRVARNWKAVPEQQRCEINAPHVDKVIPPRTHITLQLT--VNHCRSVNYLEHVQAKI 708
Query 492 TLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEI 551
TL+ RRGD+ + L SP T TLL R HD S GFN W FM+ H+W E P G W LEI
Sbjct 709 TLTSQRRGDIQLFLRSPANTSVTLLTPRIHDNSRSGFNQWPFMSVHTWGESPQGNWQLEI 768
Query 552 ENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCV 611
N + L +++L+ YGT P P S + + + +LHQ
Sbjct 769 HNEGRYMGHALLREWSLIFYGTTQSIGPNDPISVPKPSGSEATTPNSSSTTSNLHQAYSP 828
Query 612 QH--CPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLD 669
Q+ PP S+ + + P + S P L S P
Sbjct 829 QYPRIPPNNF-------GSSPSGGSKLPLGKVPPPNKSSYVTNNPLLN---SAPPKQGYQ 878
Query 670 PVEQT 674
+ T
Sbjct 879 QISAT 883
>sp|P29121|PCSK4_MOUSE Proprotein convertase subtilisin/kexin
type 4 OS=Mus musculus OX=10090 GN=Pcsk4 PE=2 SV=1
Length=655
Score = 748 bits (1932), Expect = 0.0, Method: Composition-based stats.
Identities = 350/594 (59%), Positives = 427/594 (72%), Gaps = 11/594 (2%)
Query 28 KVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGD--YYHFWHRGVTKRSLSPHRPRHS 85
++ ++WAVR+ G A +ARK GF+NLGQIF D Y+H HRGV ++SL+PH
Sbjct 29 PIYVSSWAVRVTKGYQEAERLARKFGFVNLGQIFPDDQYFHLRHRGVAQQSLTPHWGHRL 88
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
RL+++P+V+W EQQ +RR KR + PTDP F +QWY++ Q+DLN+ AW QG TG
Sbjct 89 RLKKDPKVRWFEQQTLRRRVKRSLVV-PTDPWFSKQWYMNKEIQQDLNILKAWNQGLTGR 147
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G+V+SILDDGIEK+HPDL NYDP AS+D ND DPDPQPRYT ++NRHGTRCAGEV+A
Sbjct 148 GVVISILDDGIEKDHPDLWANYDPLASYDFNDYDPDPQPRYTPNDENRHGTRCAGEVSAT 207
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDG 265
ANNG CG GVA+NARIGGVRMLDG +TD VEA+SL L P HIHIYSASWGPEDDG+TVDG
Sbjct 208 ANNGFCGAGVAFNARIGGVRMLDGAITDIVEAQSLSLQPQHIHIYSASWGPEDDGRTVDG 267
Query 266 PARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGN 325
P L +EAF RGV++GR GLG++F+WASGNGG +D+CNCDGYTNSI+TLS+ S T+ G
Sbjct 268 PGLLTQEAFRRGVTKGRQGLGTLFIWASGNGGLHYDNCNCDGYTNSIHTLSVGSTTRQGR 327
Query 326 VPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEAN 385
VPWYSEAC+ST TT+SSG + QIVTTDL +CT+ HTGTSASAPLAAG+IAL LEAN
Sbjct 328 VPWYSEACASTFTTTFSSGVVTDPQIVTTDLHHQCTDKHTGTSASAPLAAGMIALALEAN 387
Query 386 KNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVA 445
LTWRD+QHLVV+ S+PA L A DW NGVGR+VSH YGYGLLDAG +V LA+ W
Sbjct 388 PLLTWRDLQHLVVRASRPAQLQAEDWRINGVGRQVSHHYGYGLLDAGLLVDLARVWLPTK 447
Query 446 PQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNH--ITRLEHAQARLTLSYNRRGDLAI 503
PQ+KC I ++ P I R+ V K VTAC I LEH Q +L+LSY+RRGDL I
Sbjct 448 PQKKCAIRVVHTPTPILPRMLVPKNVTACSDGSRRRLIRSLEHVQVQLSLSYSRRGDLEI 507
Query 504 HLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTL 563
L SPMGTRSTL+A RP D S G+N+W FM+TH WDEDP G W L +EN N GTL
Sbjct 508 FLTSPMGTRSTLVAIRPLDISGQGYNNWIFMSTHYWDEDPQGLWTLGLENKGYYFNTGTL 567
Query 564 TKFTLVLYGTAPE--GLPVPPE----SSGCKTLTSSQACVVCEEGFSLHQKSCV 611
+TL+LYGTA + P P+ + C + C S+ C+
Sbjct 568 YYYTLLLYGTAEDMTARPQAPQVTSRARACVQRDTEGLCQESHSPLSILAGLCL 621
>sp|P30430|FUR1C_DROME Furin-like protease 1, isoform 1-CRR OS=Drosophila
melanogaster OX=7227 GN=Fur1 PE=2 SV=2
Length=1101
Score = 738 bits (1905), Expect = 0.0, Method: Composition-based stats.
Identities = 342/689 (50%), Positives = 426/689 (62%), Gaps = 37/689 (5%)
Query 30 FTNTWAVRIPGG-PAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQ 88
+T+TWAV IP G +A++VA+ HGF+NLG+IF D+YHF H V+KRSLSP +RL
Sbjct 231 YTHTWAVHIPNGDNGMADAVAKDHGFVNLGKIFDDHYHFAHHKVSKRSLSPATHHQTRLD 290
Query 89 REPQVQWLEQQVAKRRTKRDVYQ-----------------EPTDPKFPQQWYLSGVTQRD 131
+ +V W +QQ AK R+KRD + D K+PQ WYL+ D
Sbjct 291 DDDRVHWAKQQRAKSRSKRDFIRMRPSRTSSRAMSMVDAMSFNDSKWPQMWYLNRGGGLD 350
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND 191
+NV AW G TG G+VV+ILDDG+E +HPD+ NYDP AS+DVN D DP P Y +
Sbjct 351 MNVIPAWKMGITGKGVVVTILDDGLESDHPDIQDNYDPKASYDVNSHDDDPMPHYDMTDS 410
Query 192 NRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS 251
NRHGTRCAGEVAA ANN C VG+AY A +GGVRMLDG+VTDAVEARSL LNP HI IYS
Sbjct 411 NRHGTRCAGEVAATANNSFCAVGIAYGASVGGVRMLDGDVTDAVEARSLSLNPQHIDIYS 470
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
ASWGP+DDGKTVDGP LA AF G ++GRGG GSIF+WASGNGGRE D+CNCDGYTNS
Sbjct 471 ASWGPDDDGKTVDGPGELASRAFIEGTTKGRGGKGSIFIWASGNGGREQDNCNCDGYTNS 530
Query 312 IYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASA 371
I+TLSISSAT+ G+VPWYSE CSSTLATTYSSG Q EKQ+VTTDL CT SHTGTSASA
Sbjct 531 IWTLSISSATEEGHVPWYSEKCSSTLATTYSSGGQGEKQVVTTDLHHSCTVSHTGTSASA 590
Query 372 PLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDA 431
PLAAGI AL L++N+NLTWRD+QH+VV+T+KPA+L W+ NGVGR+VSHS+GYGL+DA
Sbjct 591 PLAAGIAALVLQSNQNLTWRDLQHIVVRTAKPANLKDPSWSRNGVGRRVSHSFGYGLMDA 650
Query 432 GAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARL 491
MV +A+NW V Q++C I+ K I R + +T + + LEH QA++
Sbjct 651 AEMVRVARNWKAVPEQQRCEINAPHVDKVIPPRTHITLQLT--VNHCRSVNYLEHVQAKI 708
Query 492 TLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEI 551
TL+ RRGD+ + L SP T TLL R HD S GFN W FM+ H+W E P G W LEI
Sbjct 709 TLTSQRRGDIQLFLRSPANTSVTLLTPRIHDNSRSGFNQWPFMSVHTWGESPQGNWQLEI 768
Query 552 ENTSEANNYGTLTKFTLVLYGTA----PEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQ 607
N E +T++ ++ YGT P+ + P +S+ + A E +
Sbjct 769 HN--EGRYMAQITQWDMIFYGTETPAQPDDVANPSQSNQFNLYGNDMAHNDVEYDSTGQW 826
Query 608 KSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLS-CPSH- 665
++ Q G +T + C C+ S + C CP H
Sbjct 827 RNMQQVGEVGMTRDHSNTAACLKWS-----DRKCLECNDSAYMFE----DQCYDVCPVHT 877
Query 666 ASLDPVEQTCSRQSQSSRESPPQQQPPRL 694
LD + Q P
Sbjct 878 YPLDKFQAEEDEQDDEVTRGPVNPYSSSP 906
>sp|O17798|FKPC1_CAEEL Furin-like protease kpc-1 OS=Caenorhabditis
elegans OX=6239 GN=kpc-1 PE=1 SV=3
Length=692
Score = 711 bits (1836), Expect = 0.0, Method: Composition-based stats.
Identities = 329/626 (53%), Positives = 411/626 (66%), Gaps = 46/626 (7%)
Query 21 AADAQGQKVFTNTWAVRIPGGP-AVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSP 79
+ + ++ +TN WAVRI GG AN +A K+G+ NLG I ++ R K+S S
Sbjct 49 SIASPMRRTYTNEWAVRIAGGKVEEANRLANKYGYTNLGPIIPGDEYYLFRDDRKKSRSS 108
Query 80 HRPR---HSRLQREPQVQWLEQQVAKRRTKRDV--------------------------- 109
+ R ++LQ E V W+EQQVAKRR KR
Sbjct 109 RKTRSLSANQLQHEEDVMWMEQQVAKRRVKRGYRRIRRHTDDNDIFEEDDDGTQISKSRN 168
Query 110 --YQEPTDPKFPQQWYLSGVTQR-------DLNVKAAWAQGYTGHGIVVSILDDGIEKNH 160
+ +P DP + WYL+ D NVK AW GYTG G+VV+ILDDG+E+ H
Sbjct 169 RKHPDPNDPLWTDMWYLNRGEHHSDSTTRMDHNVKEAWDLGYTGKGVVVTILDDGLERTH 228
Query 161 PDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNAR 220
PD++ NYD AS+DVND+D DP PRY ++NRHGTRCAGEVAA+ NN +C VG+AYNA
Sbjct 229 PDISPNYDERASYDVNDRDNDPMPRYEFSDENRHGTRCAGEVAAIFNNSLCIVGIAYNAN 288
Query 221 IGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQ 280
IGG+RMLDG+VTDAVEA S+G N ++I IYSASWGP+DDG+TVDGPA+L AF +G++
Sbjct 289 IGGIRMLDGDVTDAVEAASVGHNADYIDIYSASWGPDDDGRTVDGPAKLTRSAFEKGITM 348
Query 281 GRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATT 340
GR G GSIFVWASGNGG++ DSCNCDGYTNSIYTLSISSAT+ GN+PWYSEACSSTLATT
Sbjct 349 GRKGKGSIFVWASGNGGKDADSCNCDGYTNSIYTLSISSATENGNIPWYSEACSSTLATT 408
Query 341 YSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQT 400
YSSG EK I+TTDL CT HTGTSASAPLAAGI+AL LEAN NLTWRD+QH+V++T
Sbjct 409 YSSGATGEKMILTTDLHHACTNMHTGTSASAPLAAGIVALALEANPNLTWRDLQHIVIRT 468
Query 401 SKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKD 460
+KP +L A DW TNGVGR VSHS+GYGL+DAGAMV LA+ W V Q +C + K+
Sbjct 469 AKPINLRAGDWTTNGVGRNVSHSFGYGLMDAGAMVKLAKIWKKVDEQHRCRQFYPSRYKN 528
Query 461 IG--KRLEVRKTVTACLG--EPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLL 516
I RL+++ C G + N ++ +EH QA +TL +RGDL I+L SP GT+STLL
Sbjct 529 IPNGNRLQLQLYSDGCYGGADENKVSYVEHVQAIVTLKAPKRGDLQIYLTSPSGTKSTLL 588
Query 517 AARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPE 576
R D S GF DWAFMTTH+W E +G W+LEI+N + + L K+ LVLYGT E
Sbjct 589 TKRARDTSRSGFTDWAFMTTHNWGEQAAGLWILEIDN--DGWDDAELVKWELVLYGTDRE 646
Query 577 GLPVPPESSGCKTLTSSQACVVCEEG 602
+ + + S Q
Sbjct 647 TGDFGGQHASPLAVRSVQMEATSSGT 672
>sp|Q5REC2|NEC2_PONAB Neuroendocrine convertase 2 OS=Pongo abelii
OX=9601 GN=PCSK2 PE=2 SV=1
Length=638
Score = 703 bits (1813), Expect = 0.0, Method: Composition-based stats.
Identities = 279/593 (47%), Positives = 365/593 (62%), Gaps = 24/593 (4%)
Query 8 LWVVAATGTLVLLAADAQGQKVFTNTWAVRI-PGGPAVANSVARKHGFLNLGQIF-GDYY 65
A V++ A A+ + VFTN + V + GG A VA +HGF F Y
Sbjct 9 WKAAAGFLFCVMVFASAE-RPVFTNHFLVELHKGGEDEARQVAAEHGFGVRKLPFAEGLY 67
Query 66 HFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKR------DVYQEPTDPKFP 119
HF+H G+ K +L+R+P+V+ QQ R KR ++ DP F
Sbjct 68 HFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEIDINMNDPLFT 127
Query 120 QQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
+QWYL G DLNV AW GYTG G+ + I+DDGI+ HPDLA NY+ AS+
Sbjct 128 KQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASY 187
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-VT 232
D + DP P PRYT N HGTRCAGEV+A ANN +CGVGVAYN+++ G+RMLD +T
Sbjct 188 DFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMT 247
Query 233 DAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWA 292
D +EA S+ P I IYSASWGP D+GKTVDGP L +A GV++GRGG GSI+VWA
Sbjct 248 DIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWA 307
Query 293 SGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ--NEKQ 350
SG+GG +D CNCDGY +S++T+SI+SA G Y E+CSSTLA+T+S+G + E
Sbjct 308 SGDGGS-YDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAG 366
Query 351 IVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA-- 408
+ TTDL CT H+GTSA+AP AAG+ AL LEAN LTWRDMQHL V TSK L+
Sbjct 367 VATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEV 426
Query 409 NDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKR--LE 466
+ W NGVG + +H +GYG+LDAGAMV +A++W TV + C+ + +P+ I L
Sbjct 427 HQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLV 486
Query 467 VRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD 526
+ T AC G+ N + LEH QA +T++ RRGDL I++ SPMGT+S LL+ RP D +
Sbjct 487 LTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSK 546
Query 527 -GFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGL 578
GF+ W FMTTH+W ED G W LE+ A G L ++TL+L+GT
Sbjct 547 VGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEWTLMLHGTQSAPY 599
>sp|P21661|NEC2_MOUSE Neuroendocrine convertase 2 OS=Mus musculus
OX=10090 GN=Pcsk2 PE=1 SV=1
Length=637
Score = 701 bits (1809), Expect = 0.0, Method: Composition-based stats.
Identities = 276/592 (47%), Positives = 364/592 (61%), Gaps = 24/592 (4%)
Query 9 WVVAATGTLVLLAADAQGQKVFTNTWAVRI-PGGPAVANSVARKHGFLNLGQIF-GDYYH 66
W A V++ A A+ + VFTN + V + G A VA +HGF F YH
Sbjct 9 WKAAGFLFCVMVFASAE-RPVFTNHFLVELHKDGEEEARQVAAEHGFGVRKLPFAEGLYH 67
Query 67 FWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKR------DVYQEPTDPKFPQ 120
F+H G+ K +L+R+P+++ QQ R KR ++ DP F +
Sbjct 68 FYHNGLAKAKRRRSLHHKRQLERDPRIKMALQQEGFDRKKRGYRDINEIDINMNDPLFTK 127
Query 121 QWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFD 174
QWYL G DLNV AW GYTG G+ + I+DDGI+ HPDLA NY+ AS+D
Sbjct 128 QWYLFNTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLAYNYNADASYD 187
Query 175 VNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-VTD 233
+ DP P PRYT N HGTRCAGEV+A A+N +CGVGVAYN+++ G+RMLD +TD
Sbjct 188 FSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAASNNICGVGVAYNSKVAGIRMLDQPFMTD 247
Query 234 AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWAS 293
+EA S+ P I IYSASWGP D+GKTVDGP L +A GV++GRGG GSI+VWAS
Sbjct 248 IIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWAS 307
Query 294 GNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ--NEKQI 351
G+GG +D CNCDGY +S++T+SI+SA G Y E+CSSTLA+T+S+G + E +
Sbjct 308 GDGGS-YDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGV 366
Query 352 VTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA--N 409
TTDL CT H+GTSA+AP AAG+ AL LEAN +LTWRDMQHL V TSK L+ +
Sbjct 367 ATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLDLTWRDMQHLTVLTSKRNQLHDEVH 426
Query 410 DWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKR--LEV 467
W NGVG + +H +GYG+LDAGAMV +A++W TV + C+ + P+ I L +
Sbjct 427 QWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQNPEKIPPTGKLVL 486
Query 468 RKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD- 526
AC G+ N + LEH QA +T++ RRGDL I++ SPMGT+S LL+ RP D +
Sbjct 487 TLKTNACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKV 546
Query 527 GFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGL 578
GF+ W FMTTH+W ED G W LE+ A G L ++TL+L+GT
Sbjct 547 GFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGLLKEWTLMLHGTQSAPY 598
>sp|P16519|NEC2_HUMAN Neuroendocrine convertase 2 OS=Homo sapiens
OX=9606 GN=PCSK2 PE=1 SV=2
Length=638
Score = 701 bits (1809), Expect = 0.0, Method: Composition-based stats.
Identities = 279/593 (47%), Positives = 365/593 (62%), Gaps = 24/593 (4%)
Query 8 LWVVAATGTLVLLAADAQGQKVFTNTWAVRI-PGGPAVANSVARKHGFLNLGQIF-GDYY 65
A V++ A A+ + VFTN + V + GG A VA +HGF F Y
Sbjct 9 WKAAAGFLFCVMVFASAE-RPVFTNHFLVELHKGGEDKARQVAAEHGFGVRKLPFAEGLY 67
Query 66 HFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKR------DVYQEPTDPKFP 119
HF+H G+ K +L+R+P+V+ QQ R KR ++ DP F
Sbjct 68 HFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINEIDINMNDPLFT 127
Query 120 QQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
+QWYL G DLNV AW GYTG G+ + I+DDGI+ HPDLA NY+ AS+
Sbjct 128 KQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASY 187
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-VT 232
D + DP P PRYT N HGTRCAGEV+A ANN +CGVGVAYN+++ G+RMLD +T
Sbjct 188 DFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMT 247
Query 233 DAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWA 292
D +EA S+ P I IYSASWGP D+GKTVDGP L +A GV++GRGG GSI+VWA
Sbjct 248 DIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWA 307
Query 293 SGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ--NEKQ 350
SG+GG +D CNCDGY +S++T+SI+SA G Y E+CSSTLA+T+S+G + E
Sbjct 308 SGDGGS-YDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAG 366
Query 351 IVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA-- 408
+ TTDL CT H+GTSA+AP AAG+ AL LEAN LTWRDMQHL V TSK L+
Sbjct 367 VATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEV 426
Query 409 NDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKR--LE 466
+ W NGVG + +H +GYG+LDAGAMV +A++W TV + C+ + +P+ I L
Sbjct 427 HQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLV 486
Query 467 VRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD 526
+ T AC G+ N + LEH QA +T++ RRGDL I++ SPMGT+S LL+ RP D +
Sbjct 487 LTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSK 546
Query 527 -GFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGL 578
GF+ W FMTTH+W ED G W LE+ A G L ++TL+L+GT
Sbjct 547 VGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGVLKEWTLMLHGTQSAPY 599
>sp|P28841|NEC2_RAT Neuroendocrine convertase 2 OS=Rattus norvegicus
OX=10116 GN=Pcsk2 PE=1 SV=1
Length=637
Score = 700 bits (1807), Expect = 0.0, Method: Composition-based stats.
Identities = 276/592 (47%), Positives = 364/592 (61%), Gaps = 24/592 (4%)
Query 9 WVVAATGTLVLLAADAQGQKVFTNTWAVRI-PGGPAVANSVARKHGFLNLGQIF-GDYYH 66
W A V++ A A+ + VFTN + V + G A VA +HGF F YH
Sbjct 9 WKAAGLLFCVMVFASAE-RPVFTNHFLVELHKDGEEEARQVAAEHGFGVRKLPFAEGLYH 67
Query 67 FWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKR------DVYQEPTDPKFPQ 120
F+H G+ K +L+R+P+++ QQ R KR ++ DP F +
Sbjct 68 FYHNGLAKAKRRRSLHHKRQLERDPRIKMALQQEGFDRKKRGYRDINEIDINMNDPLFTK 127
Query 121 QWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFD 174
QWYL G DLNV AW GYTG G+ + I+DDGI+ HPDLA NY+ AS+D
Sbjct 128 QWYLFNTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLAYNYNSDASYD 187
Query 175 VNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-VTD 233
+ DP P PRYT N HGTRCAGEV+A A+N +CGVGVAYN+++ G+RMLD +TD
Sbjct 188 FSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAASNNICGVGVAYNSKVAGIRMLDQPFMTD 247
Query 234 AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWAS 293
+EA S+ P I IYSASWGP D+GKTVDGP L +A GV++GRGG GSI+VWAS
Sbjct 248 IIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWAS 307
Query 294 GNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ--NEKQI 351
G+GG +D CNCDGY +S++T+SI+SA G Y E+CSSTLA+T+S+G + E +
Sbjct 308 GDGGS-YDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGV 366
Query 352 VTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA--N 409
TTDL CT H+GTSA+AP AAG+ AL LEAN +LTWRDMQHL V TSK L+ +
Sbjct 367 ATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANVDLTWRDMQHLTVLTSKRNQLHDEVH 426
Query 410 DWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKR--LEV 467
W NGVG + +H +GYG+LDAGAMV +A++W TV + C+ + P+ I L +
Sbjct 427 QWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQNPEKIPPTGKLVL 486
Query 468 RKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD- 526
AC G+ N + LEH QA +T++ RRGDL I++ SPMGT+S LL+ RP D +
Sbjct 487 TLQTNACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKV 546
Query 527 GFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGL 578
GF+ W FMTTH+W ED G W LE+ A G L ++TL+L+GT
Sbjct 547 GFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGLLKEWTLMLHGTQSAPY 598
>sp|Q03333|NEC2_PIG Neuroendocrine convertase 2 OS=Sus scrofa
OX=9823 GN=PCSK2 PE=2 SV=1
Length=638
Score = 694 bits (1791), Expect = 0.0, Method: Composition-based stats.
Identities = 277/593 (47%), Positives = 364/593 (61%), Gaps = 24/593 (4%)
Query 8 LWVVAATGTLVLLAADAQGQKVFTNTWAVRI-PGGPAVANSVARKHGFLNLGQIF-GDYY 65
A V + A A+ + VFTN + V + GG A VA +HGF F Y
Sbjct 9 WKAAAGLLFCVTVFASAE-RPVFTNHFLVELHKGGEEEARQVAAEHGFGVRKLPFAEGLY 67
Query 66 HFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKR------DVYQEPTDPKFP 119
HF+H G+ K RL+R+P+V+ QQ R KR ++ DP F
Sbjct 68 HFYHNGLAKAKRRRSLHHKQRLERDPRVKRALQQEGFDRKKRGYRDINEIDINMNDPLFT 127
Query 120 QQWYL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
+QWYL G DLNV AW GYTG G+ + I+DDGI+ HPDLA NY+ AS+
Sbjct 128 KQWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASY 187
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-VT 232
D + DP P PRYT N HGTRCAGEV+A ANN +CGVGVAY++++ G+RMLD +T
Sbjct 188 DFSSNDPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYSSKVAGIRMLDQPFMT 247
Query 233 DAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWA 292
D +EA S+ P I IYSASWGP D+GKTVDGP L +A GV++GRGG GSI+VWA
Sbjct 248 DIIEASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWA 307
Query 293 SGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ--NEKQ 350
SG+GG +D CNCDGY +S++T+SI+SA G Y E+CSSTLA+T+S+G + E
Sbjct 308 SGDGGS-YDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAG 366
Query 351 IVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA-- 408
+ TTDL CT H+GTSA+AP AAG+ AL LEAN LTWRDMQHL V TSK L+
Sbjct 367 VATTDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEV 426
Query 409 NDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKR--LE 466
+ W NGVG + +H +GYG+LDAGAMV +A++W TV + C+ + +P+ I L
Sbjct 427 HQWRRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLV 486
Query 467 VRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD 526
+ T AC G+ N + LEH QA +T++ RRGDL I++ SPMGT+S LL+ RP D +
Sbjct 487 LTLTTDACEGKENFVRYLEHVQAVITVNATRRGDLNINMTSPMGTKSILLSRRPRDDDSK 546
Query 527 -GFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGL 578
GF+ W FMTTH+W ED G W LE+ A G + ++TL+L+G+
Sbjct 547 VGFDKWPFMTTHTWGEDARGTWTLELGFVGSAPQKGAVKEWTLMLHGSQSAPY 599
>sp|P30432|FUR2_DROME Furin-like protease 2 OS=Drosophila melanogaster
OX=7227 GN=Fur2 PE=2 SV=2
Length=1679
Score = 690 bits (1779), Expect = 0.0, Method: Composition-based stats.
Identities = 351/784 (45%), Positives = 421/784 (54%), Gaps = 125/784 (16%)
Query 23 DAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI--FGDYYHFWHRGVTKRSLSPH 80
+ ++TN +AV IP G +A+ +A KHGF+N GQI +YY F H V+KRSL
Sbjct 232 SIPEEAIYTNEFAVNIPAGKQMADVIATKHGFINRGQIGSLDNYYLFQHHHVSKRSLRSS 291
Query 81 RPRHSRLQREPQVQWLEQQVAKRRTKRD--------------------VYQEPT------ 114
R L+ E +V+W++QQ K R KRD +P
Sbjct 292 RKHQGALKSENEVKWMQQQHEKVRRKRDGPYQDLPTYSPYNLLRQHGGYVVDPNPHLSFS 351
Query 115 -------------------------DPKFPQQWYLSGVT--QRDLNVKAAWAQGYTGHGI 147
DP F +QWYL+G D+NV AW +GYTG G+
Sbjct 352 PESISLASHSQRMEYRDVSSHFIFPDPLFKEQWYLNGGAKDGLDMNVGPAWQKGYTGKGV 411
Query 148 VVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVAN 207
VVSILDDGI+ NHPDLA NYDP ASFD+N D DP P+ DN+HGTRCAGEVAAVA
Sbjct 412 VVSILDDGIQTNHPDLAQNYDPEASFDINGNDSDPTPQ--DNGDNKHGTRCAGEVAAVAF 469
Query 208 NGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPA 267
N CGVGVAYNA IGGVRMLDG+V D VEA++L LNP+HI IYSASWGPEDDG TVDGP
Sbjct 470 NNFCGVGVAYNASIGGVRMLDGKVNDVVEAQALSLNPSHIDIYSASWGPEDDGSTVDGPG 529
Query 268 RLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVP 327
LA AF GV+ GR G GSIFVWASGNGGR DSCNCDGYTNSI+TLSISSATQ G P
Sbjct 530 PLARRAFIYGVTSGRQGKGSIFVWASGNGGRYTDSCNCDGYTNSIFTLSISSATQAGFKP 589
Query 328 WYSEACSSTLATTYSSGNQN-EKQIVTTDLRQK------CTESHTGTSASAPLAAGIIAL 380
WY E CSSTLATTYSSG +K + T D+ CT HTGTSASAPLAAGI AL
Sbjct 590 WYLEECSSTLATTYSSGTPGHDKSVATVDMDGSLRPDHICTVEHTGTSASAPLAAGICAL 649
Query 381 TLEANKNLTWRDMQHLVVQTSKPAHLNA-NDWATNGVGRKVSHSYGYGLLDAGAMVALAQ 439
LEAN LTWRDMQ+LVV TS+PA L N W NGV RK SH +GYGL+DAGAMV+LA+
Sbjct 650 ALEANPELTWRDMQYLVVYTSRPAPLEKENGWTLNGVKRKYSHKFGYGLMDAGAMVSLAE 709
Query 440 NWTTVAPQRKCIIDILTEPKDI----GKRLEVRKTVTACLGEPNHITRLEHAQARLTLSY 495
WT+V PQ C E + I G L V C G N + LEH Q R+TL +
Sbjct 710 QWTSVPPQHICKSRENNEDRKIDGAYGSTLSTHMDVNGCAGTINEVRYLEHVQCRITLRF 769
Query 496 NRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIEN-- 553
RG+L I L SPMGT STLL RP D F+DW F++ H W E G W L++ N
Sbjct 770 FPRGNLRILLTSPMGTTSTLLFERPRDIVKSNFDDWPFLSVHFWGEKAEGRWTLQVINGG 829
Query 554 TSEANNYGTLTKFTLVLYGTAPEGLPVPPE-SSGCKTLTSSQACVVCEEGFSLHQKSC-- 610
N G L+K+ L+ YGT+ + + + E + L S + + +
Sbjct 830 RRRVNQPGILSKWQLIFYGTSTQPMRLKSELLNSSPQLRSPSSSNPFLFPSASNIGQPAN 889
Query 611 ---------------------VQHCPPGFAPQVLDTHYSTE-----NDVETI-------- 636
P A LD T + E++
Sbjct 890 EGGNFNTDSFASYLNYQNIFSSAGSDPEPATATLDGQNVTAAIAGGSSAESLGFTASAAQ 949
Query 637 ----------RASVCAPCHASCAT--CQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRE 684
+ C A C + C G T C++C SH LD TC + R
Sbjct 950 LVAAPETRDGDKKILHSCDAECDSSGCYGRGPTQCVAC-SHYRLD---NTCVSRCP-PRS 1004
Query 685 SPPQ 688
P Q
Sbjct 1005 FPNQ 1008
Score = 88.3 bits (217), Expect = 2e-16, Method: Composition-based stats.
Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 13/102 (13%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQK-SCVQHCPPGFAPQVLDTHYSTENDVETIRASV 640
P GCKT TS+ C C + ++L+++ C+ V + +E++ +
Sbjct 1161 PCQEGCKTCTSNGVCSECLQNWTLNKRDKCI----------VSGSEGCSESEFYSQVEGQ 1210
Query 641 CAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C PCHASC +C GPA T C SCP + L+ + C +
Sbjct 1211 CRPCHASCGSCNGPADTSCTSCPPNRLLE--QSRCVSGCREG 1250
Score = 60.2 bits (144), Expect = 8e-08, Method: Composition-based stats.
Identities = 24/108 (22%), Positives = 38/108 (35%), Gaps = 9/108 (8%)
Query 575 PEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
P+G + C + C C++ H + C C + + D
Sbjct 1051 PDGYFENSRNRTCVPCEPN--CASCQD----HPEYCTS-CDHHLVMHEHKCYSACPLDTY 1103
Query 635 TIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
+ CA CH++CATC GP DC++C S + C
Sbjct 1104 ETEDNKCAFCHSTCATCNGPTDQDCITCRSSRY--AWQNKCLISCPDG 1149
Score = 57.5 bits (137), Expect = 6e-07, Method: Composition-based stats.
Identities = 37/200 (19%), Positives = 52/200 (26%), Gaps = 41/200 (21%)
Query 592 SSQACVVCEEGFSLHQKSCV---QHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASC 648
S C C + CPP + ++ C CH SC
Sbjct 1347 SDFGCQKCHHYCKTCNDAGPLACTSCPPHSMLDGGLCMECLSSQYYDTTSATCKTCHDSC 1406
Query 649 ATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS--------------------------- 681
+C GP C C LD + C Q+
Sbjct 1407 RSCFGPGQFSCKGCVPPLHLDQLNSQCVSCCQNQTLAEKTSSAACCNCDGETGECKATST 1466
Query 682 ---------SRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEV--VAGLSCAFIVLVFV 730
S + + E + R L S L + +A C I+ +F
Sbjct 1467 GGKRRTVVGSGSAYKSSESKHGSFENDGNAREFVLRLDSPLTAITAIAVAICLLIITIFS 1526
Query 731 TVFLVLQLRSGFSFRGVKVY 750
+F VLQ S R Y
Sbjct 1527 IIFAVLQRNSNHVSRNSVRY 1546
Score = 57.1 bits (136), Expect = 6e-07, Method: Composition-based stats.
Identities = 24/103 (23%), Positives = 30/103 (29%), Gaps = 18/103 (17%)
Query 580 VPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRAS 639
P C S C C +G L C C G+
Sbjct 1259 CSPCLHTCSQCVSRTNCSNCSKGLELQNGECRTTCADGYYSD----------------RG 1302
Query 640 VCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
+CA C+ SC TC GP C+ CP A C +
Sbjct 1303 ICAKCYLSCHTCSGPRRNQCVQCP--AGWQLAAGECHPECPEG 1343
Score = 56.4 bits (134), Expect = 1e-06, Method: Composition-based stats.
Identities = 28/96 (29%), Positives = 37/96 (39%), Gaps = 19/96 (20%)
Query 583 ESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCA 642
+SSGC +Q CV C +CV CPP P + +C
Sbjct 972 DSSGCYGRGPTQ-CVACS--HYRLDNTCVSRCPPRSFPN---------------QVGICW 1013
Query 643 PCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQ 678
PCH +C TC G CL+C A L ++ Q
Sbjct 1014 PCHDTCETCAGAGPDSCLTCAP-AHLHVIDLAVCLQ 1048
Score = 52.5 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 22/112 (20%), Positives = 32/112 (29%), Gaps = 20/112 (18%)
Query 579 PVPPESSGCKTLTSSQA--CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETI 636
P C C + C+Q CP G+ E
Sbjct 1014 PCHDTCETCAGAGPDSCLTCAPAHL-HVIDLAVCLQFCPDGYF--------------ENS 1058
Query 637 RASVCAPCHASCATCQGPALTDCLSCPSHASLDP--VEQTCSRQSQSSRESP 686
R C PC +CA+CQ C SC H + C + + ++
Sbjct 1059 RNRTCVPCEPNCASCQD-HPEYCTSCDHHLVMHEHKCYSACPLDTYETEDNK 1109
>sp|Q9GLR0|NEC2_BOVIN Neuroendocrine convertase 2 OS=Bos taurus
OX=9913 GN=PCSK2 PE=2 SV=1
Length=638
Score = 685 bits (1768), Expect = 0.0, Method: Composition-based stats.
Identities = 277/590 (47%), Positives = 364/590 (62%), Gaps = 24/590 (4%)
Query 11 VAATGTLVLLAADAQGQKVFTNTWAVRI-PGGPAVANSVARKHGFLNLGQIF-GDYYHFW 68
A V++ A A+ + VFTN + V + GG A VA +HGF F YHF+
Sbjct 12 AAGLLFCVMVFASAE-RPVFTNHFLVELHRGGEEKARQVAAEHGFGVRKLPFAEGLYHFY 70
Query 69 HRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKR------DVYQEPTDPKFPQQW 122
H G+ K +L+R+P+V+ QQ R KR ++ DP F +QW
Sbjct 71 HNGLAKARRRRSLQHQQQLERDPRVKRALQQEGFNRKKRGYRDINEIDINVNDPLFTKQW 130
Query 123 YL------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
YL G DLNV AW GYTG G+ + I+DDGI+ HPDLA NY+ AS+D +
Sbjct 131 YLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFS 190
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-VTDAV 235
DP P PRYT N HGTRCAGEV+A ANN +CGVGVAY +++ G+RMLD +TD +
Sbjct 191 SNDPYPYPRYTDDWSNSHGTRCAGEVSAAANNNICGVGVAYGSKVAGIRMLDQPFMTDII 250
Query 236 EARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGN 295
EA S+ P I IYSASWGP D+GKTVDGP L +A GV++GRGG GSI+VWASG+
Sbjct 251 EASSISHMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGD 310
Query 296 GGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ--NEKQIVT 353
GG +D CNCDGY +S++T+SI+SA G Y E+CSSTLA+T+S+G + E + T
Sbjct 311 GGS-YDDCNCDGYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVAT 369
Query 354 TDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA--NDW 411
TDL CT H+GTSA+AP AAG+ AL LEAN LTWRDMQHL V TSK L+ + W
Sbjct 370 TDLYGNCTLRHSGTSAAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQW 429
Query 412 ATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIG--KRLEVRK 469
NGVG + +H +GYG+LDAGAMV +A++W TV + C+ + P+ I + +
Sbjct 430 RRNGVGLEFNHLFGYGVLDAGAMVKMAKDWKTVPERFHCVGGSVQNPEKIPTTGKPVLTL 489
Query 470 TVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPH-DYSADGF 528
T AC G+ N + LEH QA +T++ RRGDL I++ SPMGT+S LL+ RP D + GF
Sbjct 490 TTDACEGKENFVRYLEHVQAVVTVNATRRGDLNINMTSPMGTKSILLSRRPRGDDAKVGF 549
Query 529 NDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGL 578
+ W FMTTH+W ED G W+LE+ A G L ++TL+L+GT
Sbjct 550 DKWPFMTTHTWGEDARGTWILELGFVGSAPQKGVLMEWTLMLHGTQSAPY 599
>sp|P29146|NECA_HYDVU PC3-like endoprotease variant A OS=Hydra
vulgaris OX=6087 PE=2 SV=1
Length=793
Score = 673 bits (1736), Expect = 0.0, Method: Composition-based stats.
Identities = 261/550 (47%), Positives = 339/550 (62%), Gaps = 17/550 (3%)
Query 30 FTNTWAVRI-PGGPAVANSVARKHGFLNLGQI--FGDYYHFWHRGVTKRSLSPHRPRHSR 86
F+NTWAV I P VA+ +A+KHGF N+G+I +YHF H + +R L R + +
Sbjct 72 FSNTWAVHIDPPDNDVADRIAKKHGFTNIGKIGNIEGHYHFKHEEIGERELEKARHKTAL 131
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL------SGVTQRDLNVKAAWAQ 140
L E +V++ EQQ R KRD P DP F WYL SG D+NV W +
Sbjct 132 LNLEDEVKFAEQQKILERVKRDGI--PNDPYFKDMWYLLNTGQASGPAGVDMNVVPVWKK 189
Query 141 GYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAG 200
TG GIV+S+LDDG++ HPDL NYD AS +ND D DP PR DN HGTRCAG
Sbjct 190 NITGRGIVISVLDDGLDWTHPDLEANYDQTASIVLNDNDNDPMPR-DSDADNCHGTRCAG 248
Query 201 EVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDG 260
E AA+ANNG+CG GVAYNA+IGGVRMLDG+ TDA+EA +LG +HI IY WGP+DDG
Sbjct 249 EAAAIANNGICGTGVAYNAKIGGVRMLDGQATDALEASALGFRGDHIDIYINCWGPKDDG 308
Query 261 KTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA 320
KT P +A +A G QGR LGSIFVWA+GNGG D CNCDGYT SI+T+SI
Sbjct 309 KTFGKPGPMAAKALRLGAEQGRNRLGSIFVWATGNGGLTDDDCNCDGYTTSIFTISIGCI 368
Query 321 TQFGNVPWYSEACSSTLATTYSSGN---QNEKQIVTTDLRQKCTESHTGTSASAPLAAGI 377
G +Y+E CSSTLA T++ + E ++VTTDL +CTE GTSASAPLAAGI
Sbjct 369 GDHGLSAYYTEKCSSTLAVTFNGASHKEGRENKMVTTDLYHQCTEEFKGTSASAPLAAGI 428
Query 378 IALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVAL 437
IALTLEAN LTWRD+Q L+V T++ W NG G +H +G+G LDA AMV
Sbjct 429 IALTLEANPLLTWRDVQALIVHTAQITSPVDEGWKRNGAGFHFNHKFGFGRLDANAMVNA 488
Query 438 AQNWTTVAPQRKCIIDILTEPKDIGK--RLEVRKTVTACLGEPNHITRLEHAQARLTLSY 495
AQ+W + QRKC + +DI + L + AC I ++EH ++ +
Sbjct 489 AQSWKNLPAQRKCTAASGFDHQDIPRGDSLFINIPTVACESSSAQIAKVEHVVLTVSFVH 548
Query 496 NRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS 555
RRGD++I L+SP T+S +L+ R +D S +G ++W+FMT ++W E+P G W L+I +
Sbjct 549 RRRGDVSIDLISPKDTKSQMLSPRKYDDSDEGLDEWSFMTVYNWGENPKGIWRLKITDNP 608
Query 556 EANNYGTLTK 565
++ L
Sbjct 609 NQDDVMNLFN 618
>sp|G5ECN9|NEC2_CAEEL Neuroendocrine convertase 2 OS=Caenorhabditis
elegans OX=6239 GN=egl-3 PE=1 SV=1
Length=652
Score = 671 bits (1730), Expect = 0.0, Method: Composition-based stats.
Identities = 271/635 (43%), Positives = 363/635 (57%), Gaps = 57/635 (9%)
Query 16 TLVLLAADAQGQKVFTNTWAVRIP--GGPAVANSVARKHGFLNLGQIF--GDYYHFWHRG 71
L + + V+TN + V + GG A+ +A++HGF+N GQ+ + YHF
Sbjct 12 FLSIFIGIGEAVDVYTNHFHVHLKEGGGLEDAHRIAKRHGFINRGQVAASDNEYHFVQPA 71
Query 72 VTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKR---------------DVYQEPTDP 116
+ H++L + +V +EQ RTKR P+DP
Sbjct 72 LVHARTRRSAGHHAKLHNDDEVLHVEQLKGYTRTKRGYRPLEQRLESQFDFSAVMSPSDP 131
Query 117 KFPQQWYLSGV------TQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPG 170
+ QWYL + DLNV+ AWA G+TG I +I+DDG++ HPD+ N++
Sbjct 132 LYGYQWYLKNTGQAGGKARLDLNVERAWAMGFTGKNITTAIMDDGVDYMHPDIKNNFNAE 191
Query 171 ASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE 230
AS+D + DP P PRYT N HGTRCAGE+ A +NGVCGVGVAY+ ++ G+RMLD
Sbjct 192 ASYDFSSNDPFPYPRYTDDWFNSHGTRCAGEIVAARDNGVCGVGVAYDGKVAGIRMLDQP 251
Query 231 -VTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIF 289
+TD +EA S+G P+ IHIYSASWGP DDGKTVDGP A RGV++GR GLGSIF
Sbjct 252 YMTDLIEANSMGHEPSKIHIYSASWGPTDDGKTVDGPRNATMRAIVRGVNEGRNGLGSIF 311
Query 290 VWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQN-E 348
VWASG+GG + D CNCDGY S++T+SI+SA G Y E+CSSTLA+T+S+G +N E
Sbjct 312 VWASGDGGED-DDCNCDGYAASMWTISINSAINNGENAHYDESCSSTLASTFSNGGRNPE 370
Query 349 KQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA 408
+ TTDL +CT SH+GTSA+AP AAG+ AL LEAN +LTWRD+QHL V TS L
Sbjct 371 TGVATTDLYGRCTRSHSGTSAAAPEAAGVFALALEANPSLTWRDLQHLTVLTSSRNSLFD 430
Query 409 N------------------------DWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTV 444
+W NGVG + +H +G+G+LDA MV LA W T
Sbjct 431 GRCRDFPSLGINDNHRDSHGNCSHFEWQMNGVGLEYNHLFGFGVLDAAEMVMLAMAWKTS 490
Query 445 APQRKCIIDILTEPKDIGK--RLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLA 502
P+ C ++ P +I L + C G + LEH QA ++ + RRGD
Sbjct 491 PPRYHCTAGLIDTPHEIPADGNLILEINTDGCAGSQFEVRYLEHVQAVVSFNSTRRGDTT 550
Query 503 IHLVSPMGTRSTLLAARPH-DYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYG 561
++L+SPMGTR+ +L+ RP D S DGF +W FMTTH+W E+P+G+W L + G
Sbjct 551 LYLISPMGTRTMILSRRPKDDDSKDGFTNWPFMTTHTWGENPTGKWRLVARFQGPGAHAG 610
Query 562 TLTKFTLVLYGT--APEGLPVPPESSGCKTLTSSQ 594
TL KF L+L+GT AP L P K L + Q
Sbjct 611 TLKKFELMLHGTREAPYNLIEPIVGQTNKKLDTVQ 645
>sp|Q62849|PCSK7_RAT Proprotein convertase subtilisin/kexin type
7 OS=Rattus norvegicus OX=10116 GN=Pcsk7 PE=1 SV=1
Length=783
Score = 669 bits (1725), Expect = 0.0, Method: Composition-based stats.
Identities = 262/689 (38%), Positives = 371/689 (54%), Gaps = 43/689 (6%)
Query 33 TWAVRI---PGGPAVANSVARKH------GFLNLGQI--FGDYYHFWH---RGVTKRSLS 78
+WAV + G + + + + G +N G+I +Y F G + +
Sbjct 52 SWAVHLDSLEGERKEESLIQQANAVAQAAGLVNAGRIGELQGHYLFVQPAGHGQAMEAEA 111
Query 79 PHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGV--TQRDLNVKA 136
+ + L + V+W +Q +R KR ++ DPK+PQQW+L+ RD+NV
Sbjct 112 MRQQAEAVLAKHEAVRWHSEQRLLKRAKRSIHF--NDPKYPQQWHLNNRRSPGRDINVTG 169
Query 137 AWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGT 196
W + TG G+ V ++DDG+E D+A NY P S+D+N DPDP P + N N HGT
Sbjct 170 VWERNVTGRGVTVVVVDDGVEHTVQDIAPNYSPEGSYDLNSNDPDPMPHPDEENGNHHGT 229
Query 197 RCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGP 256
RCAGE+AAV NN C VGVAY +RI G+R+LDG +TD++EA + + IYS SWGP
Sbjct 230 RCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGP 289
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
+DDGKTVDGP +L + A GV GR G GSIFV ASGNGG+ +D+CN DGY NSIYT++
Sbjct 290 DDDGKTVDGPHQLGKAALQHGVMAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVT 349
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQK----CTESHTGTSASAP 372
I + + G +P+Y+E C+S LA T+S G++ + IVTTD + CTE HTGTSA+AP
Sbjct 350 IGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAP 409
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAG 432
LAAG+IAL L+ LTWRD+QH++V T+ + DW TN G SH +G+GLL+A
Sbjct 410 LAAGMIALMLQVRPCLTWRDVQHIIVFTATQYEDHRADWLTNEAGFSHSHQHGFGLLNAW 469
Query 433 AMVALAQNWTTVAPQRKCIIDILTEPKDIGK---RLEVRKTVTACLGEPNHITRLEHAQA 489
+V A+ WT+V + +L E K + + LEV V+ E + + LEH
Sbjct 470 RLVNAAKIWTSVPYLASYVSPMLKENKAVPRSPHSLEVLWNVSRTDLEMSGLKTLEHVAV 529
Query 490 RLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVL 549
+++++ RRG L + L P G S + A R D +GFNDW F T W E G + L
Sbjct 530 TVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGVYRL 589
Query 550 EIENTS-EANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQK 608
I + E G L ++ L LYG+ + + S L S+ + + F+L
Sbjct 590 VIRDVGDEPLQVGILQQWQLTLYGSTWSPVDIKDRQS---LLESAMSGKYLHDDFTL--- 643
Query 609 SCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASL 668
CPPG D + T N ++T+ V C + T L CLS S AS
Sbjct 644 ----PCPPGLKIPEEDGYSITPNTLKTL---VLVGCFSVFWTIY-YMLEVCLSQRSKAST 695
Query 669 DPVEQTCS---RQSQSSRESPPQQQPPRL 694
+ C QSQ+S+E + L
Sbjct 696 HGCRRGCCPWPPQSQNSKEVGTALESMPL 724
>sp|P29145|NECB_HYDVU PC3-like endoprotease variant B OS=Hydra
vulgaris OX=6087 PE=2 SV=1
Length=710
Score = 668 bits (1723), Expect = 0.0, Method: Composition-based stats.
Identities = 261/550 (47%), Positives = 339/550 (62%), Gaps = 17/550 (3%)
Query 30 FTNTWAVRI-PGGPAVANSVARKHGFLNLGQI--FGDYYHFWHRGVTKRSLSPHRPRHSR 86
F+NTWAV I P VA+ +A+KHGF N+G+I +YHF H + +R L R + +
Sbjct 72 FSNTWAVHIDPPDNDVADRIAKKHGFTNIGKIGNIEGHYHFKHEEIGERELEKARHKTAL 131
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL------SGVTQRDLNVKAAWAQ 140
L E +V++ EQQ R KRD P DP F WYL SG D+NV W +
Sbjct 132 LNLEDEVKFAEQQKILERVKRDGI--PNDPYFKDMWYLLNTGQASGPAGVDMNVVPVWKK 189
Query 141 GYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAG 200
TG GIV+S+LDDG++ HPDL NYD AS +ND D DP PR DN HGTRCAG
Sbjct 190 NITGRGIVISVLDDGLDWTHPDLEANYDQTASIVLNDNDNDPMPR-DSDADNCHGTRCAG 248
Query 201 EVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDG 260
E AA+ANNG+CG GVAYNA+IGGVRMLDG+ TDA+EA +LG +HI IY WGP+DDG
Sbjct 249 EAAAIANNGICGTGVAYNAKIGGVRMLDGQATDALEASALGFRGDHIDIYINCWGPKDDG 308
Query 261 KTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA 320
KT P +A +A G QGR LGSIFVWA+GNGG D CNCDGYT SI+T+SI
Sbjct 309 KTFGKPGPMAAKALRLGAEQGRNRLGSIFVWATGNGGLTDDDCNCDGYTTSIFTISIGCI 368
Query 321 TQFGNVPWYSEACSSTLATTYSSGN---QNEKQIVTTDLRQKCTESHTGTSASAPLAAGI 377
G +Y+E CSSTLA T++ + E ++VTTDL +CTE GTSASAPLAAGI
Sbjct 369 GDHGLSAYYTEKCSSTLAVTFNGASHKEGRENKMVTTDLYHQCTEEFKGTSASAPLAAGI 428
Query 378 IALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVAL 437
IALTLEAN LTWRD+Q L+V T++ W NG G +H +G+G LDA AMV
Sbjct 429 IALTLEANPLLTWRDVQALIVHTAQITSPVDEGWKRNGAGFHFNHKFGFGRLDANAMVNA 488
Query 438 AQNWTTVAPQRKCIIDILTEPKDIGK--RLEVRKTVTACLGEPNHITRLEHAQARLTLSY 495
AQ+W + QRKC + +DI + L + AC I ++EH ++ +
Sbjct 489 AQSWKNLPAQRKCTAASGFDHQDIPRGDSLFINIPTVACESSSAQIAKVEHVVLTVSFVH 548
Query 496 NRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS 555
RRGD++I L+SP T+S +L+ R +D S +G ++W+FMT ++W E+P G W L+I +
Sbjct 549 RRRGDVSIDLISPKDTKSQMLSPRKYDDSDEGLDEWSFMTVYNWGENPKGIWRLKITDNP 608
Query 556 EANNYGTLTK 565
++ L
Sbjct 609 NQDDVMNLFN 618
>sp|P51559|BLI4_CAEEL Endoprotease bli-4 OS=Caenorhabditis elegans
OX=6239 GN=bli-4 PE=1 SV=3
Length=942
Score = 663 bits (1711), Expect = 0.0, Method: Composition-based stats.
Identities = 306/710 (43%), Positives = 384/710 (54%), Gaps = 85/710 (12%)
Query 39 PGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQ 98
+A +A H G F D ++F + T R+ R RL P V+W+E+
Sbjct 48 KRDDELARRIAADHDMHVKGDPFLDTHYFLYHSETTRTRRHKRAIVERLDSHPAVEWVEE 107
Query 99 QVAKRRTKRDVYQEPTD--------------------------------------PKFPQ 120
Q K+R KRD D P +
Sbjct 108 QRPKKRVKRDYILLDNDVHHSNPFRRSVLNRDGTRRAQRQQPQSPREIPSLPFPDPLYKD 167
Query 121 QWYLSG--VTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ 178
QWYL G V D+NV+ AW QGY G + VSILDDGI+++HPDLA NYDP AS D+ND
Sbjct 168 QWYLHGGAVGGYDMNVRQAWLQGYAGRNVSVSILDDGIQRDHPDLAANYDPLASTDINDH 227
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEAR 238
D DP P+ DN+HGTRCAGEVAA+A N CGVGVA+ A+IGGVRMLDG V+D+VEA
Sbjct 228 DDDPTPQ--NNGDNKHGTRCAGEVAALAGNNQCGVGVAFKAKIGGVRMLDGAVSDSVEAA 285
Query 239 SLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGR 298
SL LN +HI IYSASWGPEDDGKT DGP LA EAF+RG+ GRGG G+IFVWASGNGG
Sbjct 286 SLSLNQDHIDIYSASWGPEDDGKTFDGPGPLAREAFYRGIKNGRGGKGNIFVWASGNGGS 345
Query 299 EHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQ 358
DSC+ DGYT S+YTLSISSAT + PWY E C S++ATTYSS + + IVT D+
Sbjct 346 RQDSCSADGYTTSVYTLSISSATYDNHRPWYLEECPSSIATTYSSADFRQPAIVTVDVPG 405
Query 359 KCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL-NANDWATNGVG 417
CT+ HTGTSASAPLAAGIIAL LEAN LTWRDMQHLV++T+ L N W+ NGVG
Sbjct 406 GCTDKHTGTSASAPLAAGIIALALEANPELTWRDMQHLVLRTANWKPLENNPGWSRNGVG 465
Query 418 RKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDI---LTEPKDIGKRLEVRKT--VT 472
R VS+ +GYGL+D GA+V +A+ W TV Q C + P+ I R ++ T V
Sbjct 466 RMVSNKFGYGLIDGGALVNMAKTWKTVPEQHICTYEYRLANPNPRPIVGRFQLNFTLDVN 525
Query 473 ACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWA 532
C + LEH Q T+ Y +RGDL + L SP GTRS LL RP D++A+GF+ W
Sbjct 526 GCESGT-PVLYLEHVQVHATVRYLKRGDLKLTLFSPSGTRSVLLPPRPQDFNANGFHKWP 584
Query 533 FMTTHSWDEDPSGEWVLEIEN-TSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLT 591
F++ W EDP G W+L +E+ T+ GT +TL+LYGTA P S +
Sbjct 585 FLSVQQWGEDPRGTWLLMVESVTTNPAATGTFHDWTLLLYGTADPAQSGDPVYSATPATS 644
Query 592 SSQACVVCEEGFSLHQ------------KSCVQHCPPG-----FAPQVLDTHYSTEN--- 631
V + + + +C C G A + T+
Sbjct 645 QGVLSRVHQLTSQVEESAPISFPDLTSAGNCHDECNGGCTESSSATSCFACKHLTQTLRN 704
Query 632 -------------DVETIRASVCAPCHASCATCQGPALTDCLSCPSHASL 668
D + C C + C TC C +CP L
Sbjct 705 KGGSGFKCVQKCDDTYYLDGDKCKMCSSHCHTC--TKAEVCETCPGSLLL 752
Score = 46.3 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 29/139 (21%), Positives = 39/139 (28%), Gaps = 21/139 (15%)
Query 576 EGLPVPPESSGCKTLTSSQACVVCEEGFSL---------HQKSCVQHCPPGFAPQVLDTH 626
+G SS C T T ++ C C L CV+ CPPG
Sbjct 723 DGDKCKMCSSHCHTCTKAEVCETCPGSLLLIDVDNMPHYDHGKCVESCPPGLVADYESNL 782
Query 627 YSTE---------NDVETIRASVCAPCHASCATCQGPALTDCLSCPSHA---SLDPVEQT 674
+ + C C +SC TC P C C S+
Sbjct 783 VQAKCIWRKDLCGDGYYINAVGKCDLCDSSCETCTAPGPMSCEKCSKGYGKGSIGYCRPC 842
Query 675 CSRQSQSSRESPPQQQPPR 693
C S S + +P
Sbjct 843 CPEGSTKSWQCEDCSKPDP 861
>sp|Q61139|PCSK7_MOUSE Proprotein convertase subtilisin/kexin
type 7 OS=Mus musculus OX=10090 GN=Pcsk7 PE=2 SV=2
Length=770
Score = 662 bits (1708), Expect = 0.0, Method: Composition-based stats.
Identities = 263/708 (37%), Positives = 376/708 (53%), Gaps = 43/708 (6%)
Query 6 WLLWVVAATGTLVLLAADAQGQKVFTN---TWAVRIPG--GPAVANSVARKH-------G 53
WL + V+ ++A G + +WAV + G S+ ++ G
Sbjct 22 WLELAIFFLVPQVMGLSEAGGLDILGTGGLSWAVHLDSLEGERKEESLTQQADAVAQAAG 81
Query 54 FLNLGQI--FGDYYHFWHRGVTKRSLSPHRPR---HSRLQREPQVQWLEQQVAKRRTKRD 108
+N G+I +Y F ++++ R + L R V+W +Q +R KR
Sbjct 82 LVNAGRIGELQGHYLFVQPTGHRQAMEVEAMRQQAEAVLARHEAVRWHSEQTLLKRAKRS 141
Query 109 VYQEPTDPKFPQQWYLSGV--TQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
++ DPK+PQQW+L+ RD+NV W + TG G+ V ++DDG+E D+A N
Sbjct 142 IHF--NDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTVQDIAPN 199
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
Y P S+D+N DPDP P + N N HGTRCAGE+AAV NN C VGVAY +RI G+R+
Sbjct 200 YSPEGSYDLNSNDPDPMPHPDEENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRV 259
Query 227 LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLG 286
LDG +TD++EA + + IYS SWGP+DDGKTVDGP +L + A GV GR G G
Sbjct 260 LDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVMAGRQGFG 319
Query 287 SIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ 346
SIFV ASGNGG+ +D+CN DGY NSIYT++I + + G +P+Y+E C+S LA T+S G++
Sbjct 320 SIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDK 379
Query 347 NEKQIVTTDLRQK----CTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSK 402
+ IVTTD + CTE HTGTSA+APLAAG+IAL L+ LTWRD+QH++V T+
Sbjct 380 MLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTAI 439
Query 403 PAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIG 462
+ DW TN G SH +G+GLL+A +V A+ WT+V + +L E K +
Sbjct 440 QYEDHHADWLTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPMLKENKAVP 499
Query 463 K---RLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAAR 519
+ LEV V+ E + + LEH +++++ RRG L + L P G S + A R
Sbjct 500 RSPHSLEVLWNVSRTDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPR 559
Query 520 PHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS-EANNYGTLTKFTLVLYGTAPEGL 578
D +GFN W F T W E G + L I + E G L ++ L LYG+ +
Sbjct 560 SMDSDPNGFNAWTFSTVRCWGERARGVYRLVIRDVGDEPLQMGILQQWQLTLYGSMWSPV 619
Query 579 PVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRA 638
+ S L S+ + +GF+L CPPG D + T N ++T+
Sbjct 620 DIKDRQS---LLESAMSGKYLHDGFTL-------PCPPGLKIPEEDGYTITPNTLKTL-- 667
Query 639 SVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESP 686
V C + T L CLS + AS + C + + S
Sbjct 668 -VLVGCFSVFWTIY-YMLEVCLSQRNKASTHGCRKGCCPWAPRRQNSK 713
>sp|Q9VBC7|NEC2_DROME Neuroendocrine convertase 2 OS=Drosophila
melanogaster OX=7227 GN=amon PE=1 SV=1
Length=654
Score = 661 bits (1706), Expect = 0.0, Method: Composition-based stats.
Identities = 279/596 (47%), Positives = 359/596 (60%), Gaps = 43/596 (7%)
Query 27 QKVFTNTWAVRIPGG--PAVANSVARKHGFLNLGQIFG---DYYHFWHRGVTKRSLSPHR 81
VFT+++ VR G + A+ VA K+GF NLG + G YHF HR +
Sbjct 37 PAVFTSSFLVRFRRGVDNSFAHDVADKYGFDNLGPLVGADGHEYHFKHRTLPHARSRRSL 96
Query 82 PRHSRLQREPQVQWLEQQVAKRRTKRD----------------------VYQEPTDPKFP 119
L+ P V QQ +R KR + +EPTDP FP
Sbjct 97 THTRALKSHPAVHTAVQQPGFKRVKRGLRPAVPAIHGMKFDLKVGEGNRIDEEPTDPYFP 156
Query 120 QQWYLSGVTQR------DLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
QWYL Q DLNV+AAWAQG TG + +I+DDG++ HPDL NY+ AS+
Sbjct 157 MQWYLKNTGQNGGKVRLDLNVQAAWAQGITGKNVTTAIMDDGVDYMHPDLKFNYNAEASY 216
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE-VT 232
D + DP P PRYT N HGTRCAGEVAA +NG+CGVGVAY+++I G+RMLD +T
Sbjct 217 DFSSNDPFPYPRYTDDWFNSHGTRCAGEVAAARDNGICGVGVAYDSKIAGIRMLDQPYMT 276
Query 233 DAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWA 292
D +EA S+G P+ IHIYSASWGP DDGKTVDGP A +GV++GR GLG+I+VWA
Sbjct 277 DLIEANSMGHEPHKIHIYSASWGPTDDGKTVDGPRNATMRAIVQGVNEGRNGLGNIYVWA 336
Query 293 SGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEK-QI 351
SG+GG E D CNCDGY S++T+SI+SA G Y E+CSSTLA+T+S+G ++ +
Sbjct 337 SGDGG-EEDDCNCDGYAASMWTISINSAINDGQNAHYDESCSSTLASTFSNGAKDPNTGV 395
Query 352 VTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL----N 407
TTDL KCT +H+GTSA+AP AAG+ AL LEAN LTWRD+QHL V TSK L N
Sbjct 396 ATTDLYGKCTTTHSGTSAAAPEAAGVFALALEANPQLTWRDIQHLTVLTSKRNSLFDAKN 455
Query 408 ANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDI--GKRL 465
W NGVG + +H +G+G+LDAGAMV L++ W +V P+ C LT+P+ I G+ L
Sbjct 456 RFHWTMNGVGLEFNHLFGFGVLDAGAMVTLSKQWHSVPPRYHCEAGELTQPQAIVMGRSL 515
Query 466 EVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYS- 524
AC G + LEH QA ++ + +RRGDL + L SPMGT+S +L+ R +D
Sbjct 516 FWEIKTDACKGTDTEVNYLEHVQAVISANASRRGDLELFLTSPMGTKSMILSRRANDDDH 575
Query 525 ADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPV 580
DGF W FMTTHSW E P G W LE S +G L +++LVL+GT
Sbjct 576 RDGFTKWPFMTTHSWGEYPQGTWKLEARFNSPQTRHGNLLEWSLVLHGTKEAPYRT 631
>sp|Q16549|PCSK7_HUMAN Proprotein convertase subtilisin/kexin
type 7 OS=Homo sapiens OX=9606 GN=PCSK7 PE=1 SV=2
Length=785
Score = 648 bits (1672), Expect = 0.0, Method: Composition-based stats.
Identities = 263/703 (37%), Positives = 366/703 (52%), Gaps = 48/703 (7%)
Query 33 TWAVRIPG--GPAVANSV-------ARKHGFLNLGQI--FGDYYHFWHRGVTKRSLSPHR 81
+WAV + G ++ A+ G +N G+I +Y F + +L
Sbjct 53 SWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEA 112
Query 82 PR---HSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGV--TQRDLNVKA 136
R + L V+W +Q RR KR V+ DPK+PQQW+L+ RD+NV
Sbjct 113 IRQQVEAVLAGHEAVRWHSEQRLLRRAKRSVHF--NDPKYPQQWHLNNRRSPGRDINVTG 170
Query 137 AWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGT 196
W + TG G+ V ++DDG+E D+A NY P S+D+N DPDP P N N HGT
Sbjct 171 VWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGT 230
Query 197 RCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGP 256
RCAGE+AAV NN C VGVAY +RI G+R+LDG +TD++EA + + IYS SWGP
Sbjct 231 RCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGP 290
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
+DDGKTVDGP +L + A GV GR G GSIFV ASGNGG+ +D+CN DGY NSIYT++
Sbjct 291 DDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVT 350
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQK----CTESHTGTSASAP 372
I + + G +P+Y+E C+S LA T+S G++ + IVTTD + CTE HTGTSA+AP
Sbjct 351 IGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAP 410
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAG 432
LAAG+IAL L+ LTWRD+QH++V T+ +W TN G SH +G+GLL+A
Sbjct 411 LAAGMIALMLQVRPCLTWRDVQHIIVFTATRYEDRRAEWVTNEAGFSHSHQHGFGLLNAW 470
Query 433 AMVALAQNWTTVAPQRKCIIDILTEPKDI---GKRLEVRKTVTACLGEPNHITRLEHAQA 489
+V A+ WT+V + +L E K I + LEV V+ E + + LEH
Sbjct 471 RLVNAAKIWTSVPYLASYVSPVLKENKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAV 530
Query 490 RLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVL 549
+++++ RRG L + L P G S + A R D +GFNDW F T W E G + L
Sbjct 531 TVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSDPNGFNDWTFSTVRCWGERARGTYRL 590
Query 550 EIENTS-EANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQK 608
I + E+ G L ++ L LYG+ + + + L S+ + + F+L
Sbjct 591 VIRDVGDESFQVGILRQWQLTLYGSVWSAVDIRDRQ---RLLESAMSGKYLHDDFAL--- 644
Query 609 SCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASL 668
CPPG D + T N ++T+ V C T L LS + AS
Sbjct 645 ----PCPPGLKIPEEDGYTITPNTLKTL---VLVGCFTVFWTVY-YMLEVYLSQRNVASN 696
Query 669 DPVEQTCSRQSQSSRESP--------PQQQPPRLPPEVEAGQR 703
SR++ + P EVE R
Sbjct 697 QVCRSGPCHWPHRSRKAKEEGTELESVPLCSSKDPDEVETESR 739
>sp|A0A044RE18|BLI_ONCVO Endoprotease bli OS=Onchocerca volvulus
OX=6282 GN=Bli PE=1 SV=1
Length=693
Score = 639 bits (1648), Expect = 0.0, Method: Composition-based stats.
Identities = 286/589 (49%), Positives = 362/589 (61%), Gaps = 50/589 (8%)
Query 42 PAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH-SRLQREPQVQWLEQQV 100
A+ +A++HG GQ F D ++ ++K+ + SRLQ P + +E+Q
Sbjct 50 DKKAHLIAKQHGLEIRGQPFLDGKSYFVTHISKQRSRRRKREIISRLQEHPDILSIEEQR 109
Query 101 AKRRTKRDVYQEP-------------------------------------TDPKFPQQWY 123
+ R KRD DP + +QWY
Sbjct 110 PRVRRKRDFLYPDIAHELAGSSTNIRHTGLISNTEPRIDFIQHDAPVLPFPDPLYKEQWY 169
Query 124 LSGVTQ--RDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
L+ Q D+NV+AAW GY G I VSILDDGI+++HPDLA NYDP AS D+N D D
Sbjct 170 LNNGAQGGFDMNVQAAWLLGYAGRNISVSILDDGIQRDHPDLAANYDPLASTDINGHDDD 229
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLG 241
P P+ DN+HGTRCAGEVA++A N CGVGVA++A+IGGVRMLDG V+D+VEA SL
Sbjct 230 PTPQ--DDGDNKHGTRCAGEVASIAGNVYCGVGVAFHAKIGGVRMLDGPVSDSVEAASLS 287
Query 242 LNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHD 301
LN +HI IYSASWGPEDDG+T DGP LA EAF+RGV GRGG GSIFVWASGNGG D
Sbjct 288 LNRHHIDIYSASWGPEDDGRTFDGPGPLAREAFYRGVKAGRGGKGSIFVWASGNGGSRQD 347
Query 302 SCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCT 361
SC+ DGYT S+YTLS+SSAT PWY E C ST+ATTYSS N N+ I+T D+ CT
Sbjct 348 SCSADGYTTSVYTLSVSSATIDNRSPWYLEECPSTIATTYSSANMNQPAIITVDVPHGCT 407
Query 362 ESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAH-LNANDWATNGVGRKV 420
SHTGTSASAPLAAGIIAL LEAN NLTWRDMQH+V++T+ P LN W+ NGVGR++
Sbjct 408 RSHTGTSASAPLAAGIIALALEANPNLTWRDMQHIVLRTANPVPLLNNPGWSVNGVGRRI 467
Query 421 SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTE---PKDIGKRLEVRKT--VTACL 475
++ +GYGL+DAGA+V LA W TV Q C D E P+ I ++ + V C
Sbjct 468 NNKFGYGLMDAGALVKLALIWKTVPEQHICTYDYKLEKPNPRPITGNFQMNFSLEVNGCE 527
Query 476 GEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMT 535
+ LEH Q T + +RGDL + L SP GT S LL RP D++++G + W F++
Sbjct 528 SGT-PVLYLEHVQVLATFRFGKRGDLKLTLFSPRGTSSVLLPPRPQDFNSNGIHKWPFLS 586
Query 536 THSWDEDPSGEWVLEIENTSEANNY-GTLTKFTLVLYGTAPEGLPVPPE 583
+W EDP G+W L +E+ S N GT ++L+LYGTA P P
Sbjct 587 VQTWGEDPRGKWTLMVESVSTNRNVGGTFHDWSLLLYGTAEPAQPNDPR 635
>sp|P09231|KEX1A_KLULA Protease KEX1 OS=Kluyveromyces lactis (strain
ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140
/ WM37) OX=284590 GN=KEX1 PE=3 SV=2
Length=756
Score = 562 bits (1448), Expect = 0.0, Method: Composition-based stats.
Identities = 204/556 (37%), Positives = 309/556 (56%), Gaps = 21/556 (4%)
Query 61 FGDYYHFWHR--GVTKRSLSPHRPRHSRLQRE--PQVQWLEQQVAKRRTKRDVY-----Q 111
++Y F + KR + + P VQ ++ + +
Sbjct 61 LANHYVFSKPLQSLGKRDAIDTGYSENIIDFHDLPPVQLHKRLPIGDSSMEQIQNARILF 120
Query 112 EPTDPKFPQQWYLSGV--TQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDP 169
+DP F QQW+L D+NV W + TG+G+V +++DDG++ + DL N+
Sbjct 121 NISDPLFDQQWHLINPNYPGNDVNVTGLWKENITGYGVVAALVDDGLDYENEDLKDNFCV 180
Query 170 GASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG 229
S+D ND +P P+PR + D+ HGTRCAGE+AA N+ +CGVGVAYN+++ G+R+L G
Sbjct 181 EGSWDFNDNNPLPKPR---LKDDYHGTRCAGEIAAFRND-ICGVGVAYNSKVSGIRILSG 236
Query 230 EVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIF 289
++T EA SL + IYS SWGP DDGKT+ P L ++A +GV++GR G+++
Sbjct 237 QITAEDEAASLIYGLDVNDIYSCSWGPSDDGKTMQAPDTLVKKAIIKGVTEGRDAKGALY 296
Query 290 VWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEK 349
V+ASGNGG DSCN DGYTNSI+++++ + G P YSE+CS+ + TYSSG+ N
Sbjct 297 VFASGNGGMFGDSCNFDGYTNSIFSITVGAIDWKGLHPPYSESCSAVMVVTYSSGSGN-- 354
Query 350 QIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAN 409
I TTDL +KC+ +H GTSA+APLAAGI L LEAN NLTWRD+Q+L + +S+ + +
Sbjct 355 YIKTTDLDEKCSNTHGGTSAAAPLAAGIYTLVLEANPNLTWRDVQYLSILSSEEINPHDG 414
Query 410 DWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRK 469
W +G++ SH+YG+G LDA +V +A++W V PQ + + E + I EV +
Sbjct 415 KWQDTAMGKRYSHTYGFGKLDAYNIVHMAKSWINVNPQGWLYLPTIVEKQSISNSDEVIE 474
Query 470 TVTACLGEP---NHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD 526
+ + E N++ RLEH + + RG + + L+SP G STL AR D +
Sbjct 475 STVSVSAEEFKQNNLKRLEHVTVTVDIDAPYRGHVLVDLISPDGVTSTLATARRLDKNRY 534
Query 527 GFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSG 586
GF +W FM+ W G W L++++T + N TL + L ++G + S G
Sbjct 535 GFQNWTFMSVAHWGSSGVGSWKLKVKSTHD-NEIVTLKSWRLKMFGETIDAKKAKVISYG 593
Query 587 CKTLTSSQACVVCEEG 602
+ +
Sbjct 594 NDKEDAEVKSTESKTT 609
>sp|Q09175|KRP1_SCHPO Dibasic-processing endoprotease OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=krp1
PE=1 SV=1
Length=709
Score = 560 bits (1442), Expect = 0.0, Method: Composition-based stats.
Identities = 218/593 (37%), Positives = 307/593 (52%), Gaps = 41/593 (7%)
Query 44 VANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQR---EPQVQWLEQQV 100
A ++ K+ + + YH + K S +++ + + LE+Q
Sbjct 44 AAEAIGAKY----VRPLLNLKYH----HLIKLHKGSDDSVQSSIRKRGIDAGILELERQT 95
Query 101 AKRRTKRDVYQEP------------TDPKFPQQWYL--SGVTQRDLNVKAAWAQGYTGHG 146
+ R KRD + +DP F QW++ S DLN++ W GY G
Sbjct 96 PRWRYKRDASESDELLNEFSNHFGISDPLFYGQWHIFNSNNPGHDLNLREVWDAGYFGEN 155
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ V+ +DDGI+ HPDL Y S+D ND DP P+ ++D++HGTRCAGEVAA A
Sbjct 156 VTVAFVDDGIDFKHPDLQAAYTSLGSWDFNDNIADPLPK---LSDDQHGTRCAGEVAA-A 211
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
N VCGVG+A A++ G+R+L +TDAVE+ +L HIYS SWGP DDG+ +D P
Sbjct 212 WNDVCGVGIAPRAKVAGLRILSAPITDAVESEALNYGFQTNHIYSCSWGPADDGRAMDAP 271
Query 267 ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNV 326
A GV GR GLGSIFV+ASGNGG HD+CN DGYTNSI++ +I + +
Sbjct 272 NTATRRALMNGVLNGRNGLGSIFVFASGNGGHYHDNCNFDGYTNSIFSATIGAVDAEHKI 331
Query 327 PWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANK 386
P+YSE C++ L + YSSG+ I+TT+ CT SH GTSA+APLA+ + AL L
Sbjct 332 PFYSEVCAAQLVSAYSSGS--HLSILTTNPEGTCTRSHGGTSAAAPLASAVYALALSIRP 389
Query 387 NLTWRDMQHLVVQTSKPAH--LNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTV 444
+L+WRD+QH+ V ++ P +W G + SH +G+G LDA V +A++W V
Sbjct 390 DLSWRDIQHITVYSASPFDSPSQNAEWQKTPAGFQFSHHFGFGKLDASKFVEVAKDWQVV 449
Query 445 APQRKCIIDILTEPKDIGK-------RLEVRKTVTACLGEPNHITRLEHAQARLTLSYNR 497
PQ I + K G + TVT + E ++ RLEH R+ + +NR
Sbjct 450 NPQTWLIAPEINVNKSFGSVNNETITEMVSEFTVTKDMIEKSNFKRLEHVTVRVCIPFNR 509
Query 498 RGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEA 557
RG L I L SP G RS L + RP+D ++ GF DW FMT W E P G W L + + S
Sbjct 510 RGALEILLESPSGIRSILASERPYDENSKGFLDWTFMTVQHWAEPPEGVWKLLVNDRSGG 569
Query 558 NNYGTLTKFTLVLYGTAPEGLPVPPE-SSGCKTLTSSQACVVCEEGFSLHQKS 609
+ GT + L L+G + P + + E L S
Sbjct 570 KHEGTFENWQLALWGESENPSNTAPLPYDTLELPKEMVLGIYSEPNSDLTNSS 622
>sp|P13134|KEX2_YEAST Kexin OS=Saccharomyces cerevisiae (strain
ATCC 204508 / S288c) OX=559292 GN=KEX2 PE=1 SV=1
Length=814
Score = 543 bits (1399), Expect = 0.0, Method: Composition-based stats.
Identities = 189/492 (38%), Positives = 281/492 (57%), Gaps = 12/492 (2%)
Query 114 TDPKFPQQWYLSGVT--QRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGA 171
DP F +QW+L + D+NV W TG G+V +I+DDG++ + DL N+
Sbjct 134 NDPLFERQWHLVNPSFPGSDINVLDLWYNNITGAGVVAAIVDDGLDYENEDLKDNFCAEG 193
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEV 231
S+D ND P+PR ++D+ HGTRCAGE+AA N CGVGV YNA+I G+R+L G++
Sbjct 194 SWDFNDNTNLPKPR---LSDDYHGTRCAGEIAAKKGNNFCGVGVGYNAKISGIRILSGDI 250
Query 232 TDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVW 291
T EA SL + IYS SWGP DDG+ + GP+ L ++A +GV++GR G+I+V+
Sbjct 251 TTEDEAASLIYGLDVNDIYSCSWGPADDGRHLQGPSDLVKKALVKGVTEGRDSKGAIYVF 310
Query 292 ASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQI 351
ASGNGG D+CN DGYTNSIY+++I + P YSE CS+ +A TYSSG+ + I
Sbjct 311 ASGNGGTRGDNCNYDGYTNSIYSITIGAIDHKDLHPPYSEGCSAVMAVTYSSGSG--EYI 368
Query 352 VTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAN-D 410
++D+ +C+ SH GTSA+APLAAG+ L LEAN NLTWRD+Q+L + ++ NA+ D
Sbjct 369 HSSDINGRCSNSHGGTSAAAPLAAGVYTLLLEANPNLTWRDVQYLSILSAVGLEKNADGD 428
Query 411 WATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGK---RLEV 467
W + +G+K SH YG+G +DA ++ +++ W V Q + L + LE
Sbjct 429 WRDSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLPTLYVSQSTNSTEETLES 488
Query 468 RKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADG 527
T++ + + R+EH + + RG + L+SP G S L RP D S++G
Sbjct 489 VITISEKSLQDANFKRIEHVTVTVDIDTEIRGTTTVDLISPAGIISNLGVVRPRDVSSEG 548
Query 528 FNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGC 587
F DW FM+ W E+ G+W ++++ T+E + + L L+G + + G
Sbjct 549 FKDWTFMSVAHWGENGVGDWKIKVK-TTENGHRIDFHSWRLKLFGESIDSSKTETFVFGN 607
Query 588 KTLTSSQACVVC 599
A
Sbjct 608 DKEEVEPAATES 619
>sp|O13359|KEX2_CANAW Kexin OS=Candida albicans (strain WO-1)
OX=294748 GN=KEX2 PE=3 SV=2
Length=938
Score = 521 bits (1341), Expect = 3e-171, Method: Composition-based stats.
Identities = 184/508 (36%), Positives = 286/508 (56%), Gaps = 29/508 (6%)
Query 89 REPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGV--TQRDLNVKAAWAQGYTGHG 146
Q++ + K D++ DP+F QW+L + D+NV W + G G
Sbjct 151 NHEATDEAHQKLIEIAKKLDIH----DPEFTTQWHLINLKYPGHDVNVTGLWLENILGQG 206
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
IV +++DDG++ D+ N++ S+D N++ P PR + D+ HGTRCAGE+AAV
Sbjct 207 IVTALVDDGVDAESDDIKQNFNSEGSWDFNNKGKSPLPR---LFDDYHGTRCAGEIAAVK 263
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
N+ VCG+GVA+ +++ G+R+L G +T + EA ++ + IYS SWGP D+GK + P
Sbjct 264 ND-VCGIGVAWKSQVSGIRILSGPITSSDEAEAMVYGLDTNDIYSCSWGPTDNGKVLSEP 322
Query 267 ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNV 326
+ ++A +G+ +GR G+I+V+ASGNGGR DSCN DGYTNSIY++++ + G
Sbjct 323 DVIVKKAMIKGIQEGRDKKGAIYVFASGNGGRFGDSCNFDGYTNSIYSITVGAIDYKGLH 382
Query 327 PWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANK 386
P YSEACS+ + TYSSG+ I TTD+++KC+ +H GTSA+APLA+GI +L L AN
Sbjct 383 PQYSEACSAVMVVTYSSGSGEH--IHTTDIKKKCSATHGGTSAAAPLASGIYSLILSANP 440
Query 387 NLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAP 446
NLTWRD+Q++ V ++ P + ++ T + RK SH YGYG DA MV A+ W V P
Sbjct 441 NLTWRDVQYISVLSATPINEEDGNYQTTALNRKYSHKYGYGKTDAYKMVHFAKTWVNVKP 500
Query 447 QRKCIIDILTEPKDIGKRLEVRKT---------------VTACLGEPNHITRLEHAQARL 491
Q DI+ + I E + V+ + ++ R+EH ++
Sbjct 501 QAWYYSDIIEVNQTITTTPEQKAPSKRDSPQKIIHSSVNVSEKDLKIMNVERVEHITVKV 560
Query 492 TLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEI 551
+ RG + + ++SP G S L R +D S GF +W FM+ W E GEW +E+
Sbjct 561 NIDSTYRGRVGMRIISPTGVISDLATFRVNDASTRGFQNWTFMSVAHWGETGIGEWKVEV 620
Query 552 -ENTSEANNY-GTLTKFTLVLYGTAPEG 577
+ S+ + + ++G + +G
Sbjct 621 FVDDSKGDQVEINFKDWQFRIFGESIDG 648
>sp|P42781|XPR6_YARLI Dibasic-processing endoprotease OS=Yarrowia
lipolytica (strain CLIB 122 / E 150) OX=284591 GN=XPR6 PE=3
SV=1
Length=976
Score = 522 bits (1343), Expect = 4e-171, Method: Composition-based stats.
Identities = 185/487 (38%), Positives = 275/487 (56%), Gaps = 19/487 (4%)
Query 114 TDPKFPQQWYLSGV--TQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGA 171
DP +QWYL V DLNV W + TG G+V +++DDG++ N D+ NY
Sbjct 270 KDPSLWKQWYLHNVHKAGHDLNVTGLWLRNVTGWGVVTAVVDDGLDMNAEDIKANYFAEG 329
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEV 231
S+D N DP+P +D+ HGTRCAGE+AAV NN VCGVGVAY++++ G+R+L E+
Sbjct 330 SWDFNFNKSDPKP---SSHDDYHGTRCAGEIAAVRNN-VCGVGVAYDSKVAGIRILSKEI 385
Query 232 TDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVW 291
+ +EA ++ + IYS SWGP D+G+T+ P ++ ++A ++ GR G G++FV+
Sbjct 386 AEDIEALAINYEMDKNDIYSCSWGPPDNGQTMARPGKVVKDAMVNAITNGRQGKGNVFVF 445
Query 292 ASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQI 351
ASGNGG D+CN DGYTNSIY++++ + P+YSEACS+ + TYSSG+ E I
Sbjct 446 ASGNGGSRGDNCNFDGYTNSIYSITVGALDFNDGHPYYSEACSANMVVTYSSGS--EHYI 503
Query 352 VTTDLRQ--------KCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKP 403
V TD+ +C H GTSA+APLAAG+ AL L +LTWRDMQ+L + ++
Sbjct 504 VGTDINAIDDKSAAPRCQNQHGGTSAAAPLAAGVFALALSVRPDLTWRDMQYLALYSAVE 563
Query 404 AHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGK 463
+ N + W G++ H +GYG LDA +V LA+ W V Q ++ T + +
Sbjct 564 INSNDDGWQDTASGQRFHHQFGYGKLDASKIVELAEGWNLVNNQTSFHSEVKTVSQKVKY 623
Query 464 RLEVRKTVTACLGEPNHI--TRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPH 521
++ +T + + + R EH A L L + RG + + L P G S L A R
Sbjct 624 NEPLKSVITVTRDDLDKVNFKRAEHITAVLNLEASYRGHVRVLLKGPRGVVSELAALRRD 683
Query 522 DYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVP 581
D S DG+++WAFM+ W ++ G+W L +ENT E + L + L ++G +
Sbjct 684 DRSKDGYDNWAFMSVAHWADEGEGDWELTVENTGEQDQV-ELVNWQLNVFGEQKDKREEN 742
Query 582 PESSGCK 588
E
Sbjct 743 KEGESKP 749
>sp|P91863|AEX5_CAEEL Endoprotease aex-5 OS=Caenorhabditis elegans
OX=6239 GN=aex-5 PE=1 SV=2
Length=537
Score = 417 bits (1071), Expect = 3e-136, Method: Composition-based stats.
Identities = 172/525 (33%), Positives = 256/525 (49%), Gaps = 41/525 (8%)
Query 41 GPAVANSVARKHGFLN--LGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQ 98
A + R+ GF Q + D Y KR + + + QVQ++E+
Sbjct 33 DEHDARKIGRRFGFEAQWKLQSYTDVYVGRRLRRRKRGIEDEIV--AEMMLSQQVQFIEK 90
Query 99 QVAKRRTKRDVYQEPTDPKFPQQ-WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIE 157
RR KR T+ +P W L+ L ++ AW G+ + V+++DDG++
Sbjct 91 LQGFRRYKR---APMTNKGYPVHVWNLT----PSLYIREAWEDGFNASRVTVAVVDDGVD 143
Query 158 KNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAY 217
H DL + P SFD P P+ ++ + HGT+CAG VA CG+GV +
Sbjct 144 IKHVDLKSAFSPRVSFDFVRFGDLPTPKNSKEFE--HGTQCAGLVAMEGQQ--CGLGVGH 199
Query 218 NARIGGVRMLDGE-VTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFR 276
A +G +++L + + DA+E +L + I IYS SWGP+DDGK+ + PA+ EEA
Sbjct 200 GATLGAIKLLGQDFLNDALEGDALAFQKDLIDIYSVSWGPKDDGKSAEKPAKFTEEAIKN 259
Query 277 GVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSST 336
G GR G G+IFVWASGNGG D+C DGY ++ YTLS G Y E CSS
Sbjct 260 GALHGRNGKGNIFVWASGNGGVNGDNCAYDGYVSNEYTLSFGVIDASGAPAAYGEGCSSV 319
Query 337 LATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHL 396
LA + + I TT L C+ ++++A +A+GII+L L+AN L+ RD+QHL
Sbjct 320 LAAV----SGGDAMIQTTGLESTCSSISGSSASAA-IASGIISLVLDANPTLSQRDIQHL 374
Query 397 VVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILT 456
+ +TS + + + N G G+GLL+A +V +A W VAPQ C
Sbjct 375 IARTSNASAIRDVELYENSAGLNFHPKVGFGLLNAQKLVVMAATWENVAPQVTC------ 428
Query 457 EPKDIGKRLEVRKTVTACLGEP-NHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTL 515
E + +T++E ++ + RG + I L SP GT S L
Sbjct 429 ---------EKMNLANGIIDNSDCDVTKVERVIVSGSIIHPHRGQVQIRLESPRGTISEL 479
Query 516 LAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNY 560
L RP D S D DW F++ + + E+ G W L + TSE ++
Sbjct 480 LPLRPKDTSRD-LLDWNFVSVNFFGENSRGIWKLHV--TSEEDDV 521
>sp|P23916|PRCA_TRIV2 Calcium-dependent protease OS=Trichormus
variabilis (strain ATCC 29413 / PCC 7937) OX=240292 GN=prcA
PE=1 SV=3
Length=662
Score = 349 bits (896), Expect = 1e-108, Method: Composition-based stats.
Identities = 128/536 (24%), Positives = 211/536 (39%), Gaps = 85/536 (16%)
Query 81 RPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVT------QRDLNV 134
RL E V+ ++ + +R FP QW+L T NV
Sbjct 164 FDISERLLNEESVELCHPELVREFRQRQA--------FPPQWHLKQTTIGGKTINAHANV 215
Query 135 KAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRH 194
+AAW G G +++I+DDG++ +H + + A DV + P P N + H
Sbjct 216 EAAWKLS-DGTGTIIAIIDDGVDIDHEEFRSSGKIVAPRDVTRKTNFPTPG----NRDNH 270
Query 195 GTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASW 254
GT CAG A N GVA A++ +R + + + N + S SW
Sbjct 271 GTACAG--VACGNGNFGASGVAPGAKLMPIRFVSALGSQDEADSFVWAAQNGADVISCSW 328
Query 255 GPEDD---------GKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNC 305
GP D K A +++GR G G + ++A+GNG ++S +
Sbjct 329 GPPDGTWWDDKDPLHKQKVPLPDSTRLAMDYAINKGRNGKGCVILFAAGNG---NESVDN 385
Query 306 DGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTT----------- 354
DGY + +++++ FG YS+ ++ + S N N Q
Sbjct 386 DGYASYEKVIAVAACNDFGTRSAYSDFGTAV-WCAFPSNNGNPSQTPGIWTADRTGVVGY 444
Query 355 --------DLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
D T S GTS++ P AAG+ AL L N NL W +++ ++ ++
Sbjct 445 NSGNTNLGDQAGNYTNSFGGTSSACPGAAGVAALILSRNPNLRWDEVRDIIKRSCDRIDP 504
Query 407 NANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLE 466
++ N GR S YGYG ++A V LA P + + I T +D+
Sbjct 505 VGGNY--NAEGR--SPFYGYGRINALKAVELAL------PAQPEPVSIFTAVQDVPINDL 554
Query 467 VRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD 526
++ + N I + + + + + GDL + L P S +L HD
Sbjct 555 QISQLSLAIANTNPIKSI---KVTVDIEHTYIGDLVVSLNPPA--ESGVLPIILHDRKGG 609
Query 527 GFNDWAFMTTHSWDE------------DPSGEWVLEIENTSEANNYGTLTKFTLVL 570
G +D ++DE P G W LE+ + ++A+ G + T+ L
Sbjct 610 GADD----IKQTYDEVSTPGLTALKGKIPQGTWTLEVADKAQADT-GKIRSLTIEL 660
>sp|Q59149|PRCA_NOSS1 Calcium-dependent protease OS=Nostoc sp.
(strain PCC 7120 / SAG 25.82 / UTEX 2576) OX=103690 GN=prcA
PE=3 SV=2
Length=662
Score = 347 bits (891), Expect = 6e-108, Method: Composition-based stats.
Identities = 126/536 (24%), Positives = 210/536 (39%), Gaps = 85/536 (16%)
Query 81 RPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVT------QRDLNV 134
RL E V+ ++ + +R F QQW+L T + NV
Sbjct 164 FDIAERLLNEESVELCHPELVREFRQRQA--------FSQQWHLKETTIGGKTIKAHANV 215
Query 135 KAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRH 194
+AAW G G +++I+DDG++ +H + + A DV + P P N + H
Sbjct 216 EAAWKLS-DGTGTIIAIIDDGVDVDHEEFRSSGKIVAPRDVTRKTNFPTPG----NRDNH 270
Query 195 GTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASW 254
GT CAG A N GVA A++ +R + + + N + S SW
Sbjct 271 GTACAG--VACGNGNFGASGVAPGAKLMPIRFVSALGSQDEADSFVWAAQNGADVISCSW 328
Query 255 GPEDD---------GKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNC 305
GP D K A +++GR G G + ++A+GNG ++S +
Sbjct 329 GPPDGTWWDDKDPLHKQKVPLPDSTRLAMDYAINKGRNGKGCVILFAAGNG---NESVDN 385
Query 306 DGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC----- 360
DGY + +++++ FG YS+ + + S N N Q +
Sbjct 386 DGYASYEKVIAVAACNDFGTRSAYSDFGQAV-WCAFPSNNGNPSQTPGIWTADRSGVVGY 444
Query 361 --------------TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
T S GTS++ P AAG+ AL L N NL W +++ ++ ++
Sbjct 445 NSGSTNLGDQAGNYTNSFGGTSSACPGAAGVAALILSRNPNLRWDEVRDIIKRSCDRIDP 504
Query 407 NANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLE 466
++ N GR S YGYG ++A V LA P + + I T +D+
Sbjct 505 VGGNY--NAEGR--SPFYGYGRINALKAVELAL------PAQPEPVSIFTAVQDVPINDL 554
Query 467 VRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSAD 526
++ + N I + + + + + GDL + L P +L HD
Sbjct 555 QTSQLSLAIANTNPIKSI---KVTVDIEHTYIGDLIVSLNPP--GECGVLPIILHDRKGG 609
Query 527 GFNDWAFMTTHSWDE------------DPSGEWVLEIENTSEANNYGTLTKFTLVL 570
G +D ++DE P G W LE+ + ++A+ G + T+ L
Sbjct 610 GADD----IKQTYDEVSTPGLTALKGKIPQGTWTLEVADKAQADT-GKIRSLTIEL 660
>sp|Q9L5A4|ASP_AERSO Aeromonas extracellular serine protease OS=Aeromonas
sobria OX=646 GN=asp PE=1 SV=2
Length=624
Score = 319 bits (818), Expect = 9e-98, Method: Composition-based stats.
Identities = 127/571 (22%), Positives = 207/571 (36%), Gaps = 118/571 (21%)
Query 115 DPKFPQQWYL-----------SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDL 163
+P QQWYL G+ DLN+ A G G G+ V+++DDG+ HPDL
Sbjct 53 NPLQDQQWYLLNSGQDGFSARGGIAGNDLNLWWAHRTGVLGQGVNVAVVDDGLAIAHPDL 112
Query 164 AGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGG 223
A N PG+ V D HGT +G +AAV +N + G+A A++ G
Sbjct 113 ADNVRPGSKNVVTGS----DDPTPTDPDTAHGTSVSGIIAAV-DNAIGTKGIAPRAQLQG 167
Query 224 VRMLDGEVTDAVEARSLGLNPNHI----HIYSASWG-----PEDDGK-TVDGPARLAEE- 272
+LD + L ++ +++ S+G P RL E+
Sbjct 168 FNLLDDNSQQLQKDWLYALGDSNASRDNRVFNQSYGMSVVDPRSANSLDQSQLDRLFEQQ 227
Query 273 -------AFFRGVSQGRGGL--GSIFVWASGNGGR-EHDSCNCDGYTNSIYTLSISSATQ 322
A+ + G + G + +GNG + ++ N D ++ + L +S+
Sbjct 228 TLKAQGAAYIKAAGNGFNKIAAGGYVLNRTGNGPKLPFENSNLDPSNSNFWNLVVSALNA 287
Query 323 FGNVPWYSEACSST-LATTYSSGNQNEKQIVTTDLRQ----------------------- 358
G YS S+ L+ T + +VTTDL
Sbjct 288 DGVRSSYSSVGSNIFLSATGGEYGTDTPAMVTTDLPGCDMGYNRTDDPSTNRLHGNSQLD 347
Query 359 ---KCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA------- 408
GTS++ P +G +AL + A +L+ RD++ L+ +++
Sbjct 348 ASCDYNGVMNGTSSATPSTSGAMALLMSAYPDLSVRDLRDLLARSATRVDAKHQPVMVSY 407
Query 409 -------------NDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDIL 455
W N G S +YG+GL+D + LA N + P + +
Sbjct 408 TSSTGKVRDVKGLEGWERNAAGMWFSPTYGFGLIDVNKALELAANHQPLPPLVQLPWQKI 467
Query 456 TEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTL 515
+V + T+ +E Q ++L + R DL I LVSP GTRS L
Sbjct 468 NVTGSAAAIADVGNSPTSSTTRIATPLTVEAVQVMVSLDHQRLPDLLIELVSPAGTRSIL 527
Query 516 LAA------RPHDYSADGF------NDWAFMTTHSWDEDPSGEWVLEIENTSEA------ 557
L+ + D GF D ++ + E G W LE+ + +
Sbjct 528 LSPFNSLVGQSLDQQQLGFVRTKGLRDMRMLSNKFYGESAQGTWRLEVTDVANGTRQVSL 587
Query 558 ----------------NNYGTLTKFTLVLYG 572
G L ++L + G
Sbjct 588 LNRETRERTTLTERNNRQPGKLISWSLRVLG 618
>sp|P42780|BPRX_DICNO Extracellular subtilisin-like protease OS=Dichelobacter
nodosus OX=870 PE=3 SV=1
Length=595
Score = 315 bits (806), Expect = 3e-96, Method: Composition-based stats.
Identities = 122/536 (23%), Positives = 207/536 (39%), Gaps = 104/536 (19%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ P V+++E R + P DP + QW+ ++ + W +G TG G
Sbjct 112 IASNPDVEYVEVDRWLR-----PFAAPNDPFYNDQWHYY--SEYGVKADKVWDRGITGKG 164
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVND-----QDPD-------------------- 181
+ V+++D GI NHPDL N PG+ +D QD D
Sbjct 165 VTVAVVDTGI-VNHPDLNANVIPGSGYDFIQEAEIAQDGDGRDSNPADAGDWHSNWACGK 223
Query 182 -PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
P PRY + N + HG+ AG +AAV NN + GVAY+A+I VR+L R
Sbjct 224 YPDPRYEKRNSSWHGSHVAGTIAAVTNNRIGVSGVAYDAKIVPVRVL---------GRCG 274
Query 241 GLNPN-HIHIYSASWGPEDDGKTVDGPARLAEEAF---------FRGVSQGRGGLGSIFV 290
G N + + +Y A+ G D PA++ + + + LG+ +
Sbjct 275 GYNSDINEGMYWAAGGHIDGVPDNKHPAQVINMSLGGPGVCGSTEQTLINRATQLGATII 334
Query 291 WASGNGGREHDSCNCDGYT--NSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNE 348
A+GN D+ + G T + L++ + T G ++S S + +G +
Sbjct 335 VAAGN-----DNIDAYGVTPASCDNILTVGATTSNGTRAYFSNHGSVVDISAPGAGITST 389
Query 349 KQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA----NKNLTWRDMQHLVVQTSKPA 404
GTS + P AG+ AL + A NK +T ++ ++V+T
Sbjct 390 VDSGARYPSGPSYSLMDGTSMATPHVAGVAALVISAANSVNKEMTPAQVRDVLVRTVS-- 447
Query 405 HLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTV----------APQRKCIIDI 454
+ NG + G G++DA A V + V A R I +
Sbjct 448 -------SFNGTPDR---RIGAGIVDADAAVNAVLDGNVVERPIDELKPQAEYRNPQIKL 497
Query 455 LTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRST 514
+ + + + ++V G P + A + + + L + LVSP G
Sbjct 498 IRDYQMMFSEIKVN-------GRPGNTK---FAVVKADIRHTDPSQLKLRLVSPKGYEYA 547
Query 515 LLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVL 570
+ + S++ + T DE +G W L+I +T G +++
Sbjct 548 VHYDNIKNKSSE-------LITFPRDEQMNGYWRLKIVDTKRGVT-GYTRGWSVAF 595
>sp|P42779|BPRV_DICNO Extracellular basic protease OS=Dichelobacter
nodosus OX=870 GN=bprV PE=1 SV=1
Length=603
Score = 291 bits (745), Expect = 2e-87, Method: Composition-based stats.
Identities = 126/531 (24%), Positives = 205/531 (39%), Gaps = 88/531 (17%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ P V+++E P DP + QQW+ G + W +G+TG G
Sbjct 114 IASNPDVEFVEVDRLAY-----PKAAPNDPSYRQQWHYFG--NYGVKANKVWDRGFTGQG 166
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASF----------DVNDQDPD--------------P 182
+VVS++D GI +H DL GN PG F D D +P P
Sbjct 167 VVVSVVDTGI-LDHVDLNGNMLPGYDFISSAPNARDGDQRDNNPADEGDWFDNWDCGGYP 225
Query 183 QPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML------DGEVTDAVE 236
PR + HG+ AG +AAV NNGV GVAY A++ VR+L D ++TD +
Sbjct 226 DPRREKKFSTWHGSHVAGTIAAVTNNGVGVAGVAYGAKVIPVRVLGKCGGYDSDITDGMY 285
Query 237 ARSLGL------NPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFV 290
+ G N N + + S G G R+ ++ LG++ V
Sbjct 286 WSAGGHIDGVPDNQNPAQVVNMSLGG--GGGCSQNSQRMIDKTT---------NLGALIV 334
Query 291 WASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQ 350
A+GN ++ ++ LS+ + T G +S + + +
Sbjct 335 IAAGNENQDASRTWP---SSCNNVLSVGATTPKGKRAPFSNYGARVHLAAPGTNILSTID 391
Query 351 IVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA----NKNLTWRDMQHLVVQTSKPAHL 406
+ + GTS +AP +G+ AL + A K LT ++ ++V+T+
Sbjct 392 VGQAGPVRSSYGMKAGTSMAAPHVSGVAALVISAANSIGKTLTPSELSDILVRTTSRF-- 449
Query 407 NANDWATNGVGRKVSHSYGYGLLDAGAMVALA---QNWTTVAPQRKCIIDILTEPKDIGK 463
NG ++ G G++DA A V QN P I+ + +
Sbjct 450 -------NG---RLDRGLGSGIVDANAAVNAVLGDQNRAQPRPPVNQPINSGNKVYRSDR 499
Query 464 RLEVRKTVTACLG-EPNHITRLEHAQARLTLS--YNRRGDLAIHLVSPMGTRSTLLAARP 520
R+ +R + G N R+ A LTL Y R LA+ L++P G +
Sbjct 500 RVAIRDLRSVTSGIRVNDQARVGSANITLTLDIRYGDRSQLAVELIAPSGR----VYPIY 555
Query 521 HDYSAD-GFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVL 570
HD A + + E G W L++ + + G++ ++L
Sbjct 556 HDGKRQPNIVGPATFSVKN--ERLQGTWTLKVTDKARGVT-GSIDSWSLTF 603
>sp|P31339|ASPA_AERSA Microbial serine proteinase OS=Aeromonas
salmonicida OX=645 GN=aspA PE=1 SV=1
Length=621
Score = 277 bits (709), Expect = 6e-82, Method: Composition-based stats.
Identities = 114/525 (22%), Positives = 180/525 (34%), Gaps = 98/525 (19%)
Query 125 SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF------DVNDQ 178
G+ DLN+ A G GI V+++DDG+ HPDLA N PG+ D
Sbjct 70 GGMAGNDLNLWWAHRTEVLGQGINVAVVDDGLAIAHPDLADNVRPGSKNVVTGGSDPTPT 129
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEAR 238
DPD PR++ +G +AAV +N + +GVA ++ G +LD + +
Sbjct 130 DPDRCPRHS----------VSGIIAAV-DNSIGTLGVAPRVQLQGFNLLDDNIQQLQKDW 178
Query 239 SLGLN-------PNHIHIYSASWGPEDDGKTVDGPA--RLAEEAFFRGVSQGRGGLGSIF 289
L P S + +D RL E+ + G+ F
Sbjct 179 LYALGQRRHRRQPGLQPELRMSLVDPEGANGLDQVQLDRLFEQRTQHASAAYIKAAGTAF 238
Query 290 V-WASGNGGR---------EHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLAT 339
A+GN ++ N D ++ + L + + G YS S+ +
Sbjct 239 SRIAAGNYVAQPHRNLPKLPFENSNIDPSNSNFWNLVVRAINADGVRSSYSSVGSNVFLS 298
Query 340 TYSSGNQNE-KQIVTTDLRQ--------------------------KCTESHTGTSASAP 372
+ +VTTDL GTS++ P
Sbjct 299 APGGEYGTDAPAMVTTDLPGCDMGYNRVDDPSTNRLHNNPQLDASCDYNGVMNGTSSATP 358
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAN--------------------DWA 412
G + L + +L+ RD++ L+ + + N W
Sbjct 359 NTTGAMVL-MAPYPDLSVRDLRDLLARNATRLDANQGPVQINYTAANGERRQVTGLEGWE 417
Query 413 TNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIG--KRLEVRKT 470
N G S SYG+GL+D ++ T A + V +
Sbjct 418 RNAAGLWYSPSYGFGLVDVNKTQPCSRQPRTAATTGAVALAKGKGNGRSPSAPSRYVGSS 477
Query 471 VTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAAR------PHDYS 524
T + + +E Q ++L + R DL I LVSP GTRS LL D
Sbjct 478 PTRSSTQVDQPLTVEAVQVMVSLDHQRLPDLLIELVSPSGTRSVLLNPNNSLVGQSLDRQ 537
Query 525 ------ADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTL 563
G D ++ + E GEW LE+ + + A +L
Sbjct 538 QLGYVRTKGLRDMRMLSHKFYGEPAHGEWRLEVTDVANAAAQVSL 582
>sp|P16396|SUBE_BACSU Minor extracellular protease Epr OS=Bacillus
subtilis (strain 168) OX=224308 GN=epr PE=1 SV=1
Length=645
Score = 234 bits (596), Expect = 9e-66, Method: Composition-based stats.
Identities = 101/432 (23%), Positives = 170/432 (39%), Gaps = 69/432 (16%)
Query 69 HRGVTKRSLSPHRPRHSRLQREPQVQWLEQQV---AKRRTKRDVYQEPTDPKFP-QQWYL 124
++ + +++ + L+++P + ++E V A T V + TD +QW L
Sbjct 59 YKHLPAVAVTADQETVKELKQDPDILYVENNVSFTAADSTDFKVLSDGTDTSDNFEQWNL 118
Query 125 SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQP 184
+ VK AW G TG I ++++D GI H DL+ G S
Sbjct 119 EPI-----QVKQAWKAGLTGKNIKIAVIDSGISP-HDDLS--IAGGYS--------AVSY 162
Query 185 RYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN- 243
+ +DN HGT AG + A +NG G+A A+I V+ LD + +++ G++
Sbjct 163 TSSYKDDNGHGTHVAGIIGA-KHNGYGIDGIAPEAQIYAVKALDQNGSGDLQSLLQGIDW 221
Query 244 --PNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHD 301
N + I + S G D K + +A+ + G + V ASGN G
Sbjct 222 SIANRMDIVNMSLGTTSDSKILHD---AVNKAYEQ---------GVLLVAASGNDGNGKP 269
Query 302 SCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCT 361
Y++ +++S+ + + +S +S+ N +T+ +
Sbjct 270 VNYPAAYSS---VVAVSATNEKNQLASFSTTGD---EVEFSAPGTN----ITSTYLNQYY 319
Query 362 ESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVS 421
+ +GTS + P AA + AL L RD VQ + N D T G ++
Sbjct 320 ATGSGTSQATPHAAAMFAL-------LKQRDPAETNVQLREEMRKNIVDLGTAGRDQQ-- 370
Query 422 HSYGYGLLDAGAMV-----ALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLG 476
+GYGL+ A A A+ A Q K ID I K E+ +
Sbjct 371 --FGYGLIQYKAQATDSAYAAAEQAVKKAEQTKAQID-------INKARELISQLPNSDA 421
Query 477 EPNHITRLEHAQ 488
+ RL+ Q
Sbjct 422 KTALHKRLDKVQ 433
>sp|Q99405|PRTM_SHOC1 M-protease OS=Shouchella clausii (strain
KSM-K16) OX=66692 GN=aprE PE=1 SV=2
Length=380
Score = 222 bits (566), Expect = 3e-64, Method: Composition-based stats.
Identities = 85/353 (24%), Positives = 137/353 (39%), Gaps = 68/353 (19%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+ +P + ++E+ + V W +S V AA +G TG
Sbjct 91 DALELDPTISYIEEDAEVTTMAQSV-----------PWGISRV-----QAPAAHNRGLTG 134
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G+ V++LD GI HPDL N GASF + + + N HGT AG +AA
Sbjct 135 SGVKVAVLDTGIS-THPDL--NIRGGASFVPGE--------PSTQDGNGHGTHVAGTIAA 183
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGL---NPNHIHIYSASWGPEDDGK 261
+ NN + +GVA +A + V++L + +V + + GL N +H+ + S G
Sbjct 184 L-NNSIGVLGVAPSAELYAVKVLGASGSGSVSSIAQGLEWAGNNGMHVANLSLGSPSPSA 242
Query 262 TVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
T++ G + V ASGN G S Y N+ +++ +
Sbjct 243 TLEQ------------AVNSATSRGVLVVAASGNSGAGSISYPAR-YANA---MAVGATD 286
Query 322 QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALT 381
Q N +S+ + V + S GTS + P AG+ AL
Sbjct 287 QNNNRASFSQYGAGLDIVAPG-------VNVQSTYPGSTYASLNGTSMATPHVAGVAALV 339
Query 382 LEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAM 434
+ N +W ++Q N G ++ YG GL++A A
Sbjct 340 KQKNP--SWSNVQI------------RNHLKNTATGLGNTNLYGSGLVNAEAA 378
>sp|Q00139|VG47_ICHVA Subtilisin-like protease OS=Ictalurid herpesvirus
1 (strain Auburn) OX=766178 GN=ORF47 PE=3 SV=2
Length=370
Score = 221 bits (562), Expect = 1e-63, Method: Composition-based stats.
Identities = 78/309 (25%), Positives = 127/309 (41%), Gaps = 48/309 (16%)
Query 249 IYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY 308
+ S SWG DDG + R +GR GLG++ + +GNGG D C DG+
Sbjct 84 VVSESWGCVDDGAAFCDTTGNFRDHRGRVAREGRDGLGTVLIRPAGNGG-PIDDCGADGF 142
Query 309 TNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTS 368
T +I T+ + SE C++ L T T KC + +S
Sbjct 143 TQAIGTVVTTVTDYT-----RSERCAAVLVTVPPPNE-------TVWYDGKCGFIPSSSS 190
Query 369 ASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN---ANDWATNGVGRKVSH-SY 424
A+ P+ ++ + A+ LT R +Q ++V+ +KP + W N V + +H ++
Sbjct 191 AAPPILGNMLLALIRAHPTLTLRMIQRILVRAAKPVTVTGWRGRGWWLNRVTDRWTHRNF 250
Query 425 GYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEV---RKTVTACLGEPNHI 481
G+G V+P R +I R E+ R V + +
Sbjct 251 GFG---------------EVSPSR----------LEIEARRELSTSRAPVAWSTLDTCDL 285
Query 482 TRLEHAQARLTLS-YNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD 540
+ +E + RL ++ RG + + + SP GT +L RP D+S D F T W
Sbjct 286 SEVEWVRVRLGIAPAVFRGGVTVEISSPSGTIIEILGKRPLDFSRDEFE--GEFVTPFWG 343
Query 541 EDPSGEWVL 549
E G+W +
Sbjct 344 EPGRGKWTV 352
>sp|P27693|ELYA_ALKAL Alkaline protease OS=Alkalihalobacillus
alcalophilus OX=1445 PE=1 SV=1
Length=380
Score = 220 bits (559), Expect = 3e-63, Method: Composition-based stats.
Identities = 85/353 (24%), Positives = 135/353 (38%), Gaps = 68/353 (19%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+ +P + ++E+ + V W +S V AA +G TG
Sbjct 91 DALELDPAISYIEEDAEVTTMAQSV-----------PWGISRV-----QAPAAHNRGLTG 134
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G+ V++LD GI HPDL N GASF + + + N HGT AG +AA
Sbjct 135 SGVKVAVLDTGIS-THPDL--NIRGGASFVPGE--------PSTQDGNGHGTHVAGTIAA 183
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGL---NPNHIHIYSASWGPEDDGK 261
+ NN + +GVA NA + V++L + +V + + GL N +H+ + S G
Sbjct 184 L-NNSIGVLGVAPNAELYAVKVLGASGSGSVSSIAQGLEWAGNNGMHVANLSLGSPSPSA 242
Query 262 TVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
T++ G + V ASGN G S Y N+ +++ +
Sbjct 243 TLEQ------------AVNSATSRGVLVVAASGNSGAGSISYPAR-YANA---MAVGATD 286
Query 322 QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALT 381
Q N +S+ + V + S GTS + P AG AL
Sbjct 287 QNNNRASFSQYGAGLDIVAPG-------VNVQSTYPGSTYASLNGTSMATPHVAGAAALV 339
Query 382 LEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAM 434
+ N +W ++Q N ++ YG GL++A A
Sbjct 340 KQKNP--SWSNVQI------------RNHLKNTATSLGSTNLYGSGLVNAEAA 378
>sp|P41362|ELYA_SHOCL Alkaline protease OS=Shouchella clausii
OX=79880 PE=1 SV=1
Length=380
Score = 218 bits (554), Expect = 1e-62, Method: Composition-based stats.
Identities = 84/353 (24%), Positives = 135/353 (38%), Gaps = 68/353 (19%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+ +P + ++E+ + V W +S V AA +G TG
Sbjct 91 DALELDPAISYIEEDAEVTTMAQSV-----------PWGISRV-----QAPAAHNRGLTG 134
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G+ V++LD GI HPDL N GASF + + + N HGT AG +AA
Sbjct 135 SGVKVAVLDTGIS-THPDL--NIRGGASFVPGE--------PSTQDGNGHGTHVAGTIAA 183
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGL---NPNHIHIYSASWGPEDDGK 261
+ NN + +GVA +A + V++L + +V + + GL N +H+ + S G
Sbjct 184 L-NNSIGVLGVAPSAELYAVKVLGASGSGSVSSIAQGLEWAGNNGMHVANLSLGSPSPSA 242
Query 262 TVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
T++ G + V ASGN G S Y N+ +++ +
Sbjct 243 TLEQ------------AVNSATSRGVLVVAASGNSGAGSISYPAR-YANA---MAVGATD 286
Query 322 QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALT 381
Q N +S+ + V + S GTS + P AG AL
Sbjct 287 QNNNRASFSQYGAGLDIVAPG-------VNVQSTYPGSTYASLNGTSMATPHVAGAAALV 339
Query 382 LEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAM 434
+ N +W ++Q N ++ YG GL++A A
Sbjct 340 KQKNP--SWSNVQI------------RNHLKNTATSLGSTNLYGSGLVNAEAA 378
>sp|P58502|TKSU_THEKO Tk-subtilisin OS=Thermococcus kodakarensis
(strain ATCC BAA-918 / JCM 12380 / KOD1) OX=69014 GN=TK1675
PE=1 SV=1
Length=422
Score = 217 bits (553), Expect = 7e-62, Method: Composition-based stats.
Identities = 84/378 (22%), Positives = 144/378 (38%), Gaps = 56/378 (15%)
Query 86 RLQREPQVQWLE--QQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYT 143
+L++ P V+ +E Q + T P W + V + W+
Sbjct 74 KLKKMPGVEKVEFDHQAVLLGKPSWLGGGSTQPAQTIPWGIERV-----KAPSVWSITDG 128
Query 144 GHGIV-VSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEV 202
++ V++LD G++ +HPDLA N S + + N HGT G +
Sbjct 129 SVSVIQVAVLDTGVDYDHPDLAANIAWCVS---TLRGKVSTKLRDCADQNGHGTHVIGTI 185
Query 203 AAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLG-----LNPNHIHIYSA----S 253
AA+ NN + VGVA +I VR+LD + + ++G L P+ + +
Sbjct 186 AAL-NNDIGVVGVAPGVQIYSVRVLDARGSGSYSDIAIGIEQAILGPDGVADKDGDGIIA 244
Query 254 WGPEDD-----GKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY 308
P+DD ++ GP A++++ + G + V ASGN G S Y
Sbjct 245 GDPDDDAAEVISMSLGGP---ADDSYLYDMIIQAYNAGIVIVAASGNEGAPSPSYPA-AY 300
Query 309 TNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTS 368
+++ + N+ +S + I++T E+ GTS
Sbjct 301 PE---VIAVGAIDSNDNIASFSNRQ--------PEVSAPGVDILST-YPDDSYETLMGTS 348
Query 369 ASAPLAAGIIALTLEAN--------KNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
+ P +G++AL A T+ D+ V+ H+ A+D G
Sbjct 349 MATPHVSGVVALIQAAYYQKYGKILPVGTFDDISKNTVRGI--LHITADDLGPTG----W 402
Query 421 SHSYGYGLLDAGAMVALA 438
YGYG++ A V A
Sbjct 403 DADYGYGVVRAALAVQAA 420
>sp|Q93LQ6|FLS_FERPE Fervidolysin OS=Fervidobacterium pennivorans
OX=93466 GN=fls PE=1 SV=1
Length=699
Score = 223 bits (567), Expect = 2e-61, Method: Composition-based stats.
Identities = 86/394 (22%), Positives = 145/394 (37%), Gaps = 64/394 (16%)
Query 70 RGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRR------TKRDVYQEPTDPKFPQQWY 123
+ + + + P + R +P V + K R T RD +E ++ + W
Sbjct 110 KALALKGIRYVEPSYKRELIKPTVVKPNPDMYKIRKPGLNSTARDYGEELSN----ELWG 165
Query 124 LSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQ 183
L + + W + +G I+V+++D G++ HPDL G G +++ P
Sbjct 166 LEAIGV----TQQLWEEA-SGTNIIVAVVDTGVDGTHPDLEGQVIAGYRPAFDEELPAGT 220
Query 184 PRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD--------GEVTDAV 235
HGT AG +AA +G VGVA A+I + + D G V D
Sbjct 221 ---DSSYGGSHGTHVAGTIAA-KKDGKGIVGVAPGAKIMPIVIFDDPALVGGNGYVGDDY 276
Query 236 EARSLGLNPNH-IHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASG 294
A + +H + + SWG T+ +EAF + G + V ++G
Sbjct 277 VAAGIIWATDHGAKVMNHSWGGWGYSYTM-------KEAFDYAMEH-----GVVMVVSAG 324
Query 295 NGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACS------------STLATTYS 342
N + GY I ++ V +S ST+ S
Sbjct 325 NNTSDSHHQYPAGYPGVIQVAALDYYGGTFRVAGFSSRSDGVSVGAPGVTILSTVPGEDS 384
Query 343 SGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSK 402
G + + V + + GTS +AP G++A+ L+ N ++ L+ T+
Sbjct 385 IGYEGHNENVPAT-NGGTYDYYQGTSMAAPHVTGVVAVLLQKFPNAKPWQIRKLLENTA- 442
Query 403 PAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
N N W H GYGL+ A +
Sbjct 443 -FDFNGNGW---------DHDTGYGLVKLDAALQ 466
>sp|P04189|SUBT_BACSU Subtilisin E OS=Bacillus subtilis (strain
168) OX=224308 GN=aprE PE=1 SV=3
Length=381
Score = 211 bits (538), Expect = 3e-60, Method: Composition-based stats.
Identities = 76/358 (21%), Positives = 135/358 (38%), Gaps = 68/358 (19%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+++P V ++E+ + V P Q + A +QGYTG
Sbjct 86 KELKKDPSVAYVEEDHIAHEYAQSV------PYGISQ----------IKAPALHSQGYTG 129
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
+ V+++D GI+ +HPDL N GASF ++ +P + + HGT AG +AA
Sbjct 130 SNVKVAVIDSGIDSSHPDL--NVRGGASFVPSETNP-------YQDGSSHGTHVAGTIAA 180
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNHIHIYSASWGPEDDGK 261
+ NN + +GVA +A + V++LD + G+ N++ + + S G
Sbjct 181 L-NNSIGVLGVAPSASLYAVKVLDSTGSGQYSWIINGIEWAISNNMDVINMSLGGPTGST 239
Query 262 TVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSC---NCDGYTNSIYTLSIS 318
+ + ++A G + A+GN G + Y + T+++
Sbjct 240 ALK---TVVDKAVSS---------GIVVAAAAGNEGSSGSTSTVGYPAKYPS---TIAVG 284
Query 319 SATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGII 378
+ +S A S + + L ++ GTS + P AG
Sbjct 285 AVNSSNQRASFSSAGSELDVMAPGVS-------IQSTLPGGTYGAYNGTSMATPHVAGAA 337
Query 379 ALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
AL L + T ++ + T+ S YG GL++ A
Sbjct 338 ALILSKHPTWTNAQVRDRLESTATY--------------LGNSFYYGKGLINVQAAAQ 381
>sp|P35835|SUBN_BACNA Subtilisin NAT OS=Bacillus subtilis subsp.
natto OX=86029 GN=aprN PE=1 SV=1
Length=381
Score = 211 bits (537), Expect = 4e-60, Method: Composition-based stats.
Identities = 75/358 (21%), Positives = 134/358 (37%), Gaps = 68/358 (19%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+++P V ++E+ + V P Q + A +QGYTG
Sbjct 86 KELKKDPSVAYVEEDHIAHEYAQSV------PYGISQ----------IKAPALHSQGYTG 129
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
+ V+++D GI+ +HPDL N GASF ++ +P + + HGT AG +AA
Sbjct 130 SNVKVAVIDSGIDSSHPDL--NVRGGASFVPSETNP-------YQDGSSHGTHVAGTIAA 180
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNHIHIYSASWGPEDDGK 261
+ NN + +GVA +A + V++LD + G+ N++ + + S G
Sbjct 181 L-NNSIGVLGVAPSASLYAVKVLDSTGSGQYSWIINGIEWAISNNMDVINMSLGGPTGST 239
Query 262 TVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSC---NCDGYTNSIYTLSIS 318
+ + ++A G + A+GN G + Y + T+++
Sbjct 240 ALK---TVVDKAVSS---------GIVVAAAAGNEGSSGSTSTVGYPAKYPS---TIAVG 284
Query 319 SATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGII 378
+ +S S + + L ++ GTS + P AG
Sbjct 285 AVNSSNQRASFSSVGSELDVMAPGVS-------IQSTLPGGTYGAYNGTSMATPHVAGAA 337
Query 379 ALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
AL L + T ++ + T+ S YG GL++ A
Sbjct 338 ALILSKHPTWTNAQVRDRLESTATY--------------LGNSFYYGKGLINVQAAAQ 381
>sp|P20724|ELYA_BACYA Alkaline elastase YaB OS=Bacillus sp. (strain
YaB) OX=72578 GN=ale PE=1 SV=1
Length=378
Score = 209 bits (532), Expect = 2e-59, Method: Composition-based stats.
Identities = 82/353 (23%), Positives = 139/353 (39%), Gaps = 69/353 (20%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+ +P + ++E+ + W ++ V A ++G+TG
Sbjct 90 DALELDPAIAYIEEDAEVTTMQTVP------------WGINRV-----QAPIAQSRGFTG 132
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G+ V++LD GI NH DL GASF + + N HGT+ AG +AA
Sbjct 133 TGVRVAVLDTGIS-NHADL--RIRGGASFVPGE--------PNISDGNGHGTQVAGTIAA 181
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNHIHIYSASWGPEDDGK 261
+ NN + +GVA N + GV++L + ++ + GL N +HI + S G
Sbjct 182 L-NNSIGVLGVAPNVDLYGVKVLGASGSGSISGIAQGLQWAANNGMHIANMSLGSSAGSA 240
Query 262 TVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
T+ E+A + + G + V ASGN G + Y N+ +++ +
Sbjct 241 TM-------EQAVNQATAS-----GVLVVAASGNSGAGNVGFPAR-YANA---MAVGATD 284
Query 322 QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALT 381
Q N +S+ + G V + + S GTS + P AG+ AL
Sbjct 285 QNNNRATFSQYGAGLDIVAPGVG-------VQSTVPGNGYASFNGTSMATPHVAGVAALV 337
Query 382 LEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAM 434
+ N +W ++Q N + +G GL++A A
Sbjct 338 KQKNP--SWSNVQI------------RNHLKNTATNLGNTTQFGSGLVNAEAA 376
>sp|P29599|SUBB_LEDLE Subtilisin BL OS=Lederbergia lenta OX=1467
PE=1 SV=1
Length=269
Score = 206 bits (523), Expect = 2e-59, Method: Composition-based stats.
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 57/316 (18%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W +S V AA +G TG G+ V++LD GI HPDL N GASF +
Sbjct 6 WGISRV-----QAPAAHNRGLTGSGVKVAVLDTGIS-THPDL--NIRGGASFVPGE---- 53
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLG 241
+ + N HGT AG +AA+ NN + +GVA +A + V++L + A+ + + G
Sbjct 54 ----PSTQDGNGHGTHVAGTIAAL-NNSIGVLGVAPSAELYAVKVLGADGRGAISSIAQG 108
Query 242 L---NPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGR 298
L N +H+ + S G T++ G + V ASGN G
Sbjct 109 LEWAGNNGMHVANLSLGSPSPSATLEQ------------AVNSATSRGVLVVAASGNSGA 156
Query 299 EHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQ 358
S Y N+ +++ + Q N +S+ + V +
Sbjct 157 SSISYPAR-YANA---MAVGATDQNNNRASFSQYGAGLDIVAPG-------VNVQSTYPG 205
Query 359 KCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
S GTS + P AG AL + N +W ++Q N
Sbjct 206 STYASLNGTSMATPHVAGAAALVKQKNP--SWSNVQI------------RNHLKNTATSL 251
Query 419 KVSHSYGYGLLDAGAM 434
++ YG GL++A A
Sbjct 252 GSTNLYGSGLVNAEAA 267
>sp|P29143|HLY_NATA1 Halolysin OS=Natrialba asiatica (strain ATCC
700177 / DSM 12278 / JCM 9576 / FERM P-10747 / NBRC 102637
/ 172P1) OX=29540 GN=hly PE=1 SV=1
Length=530
Score = 213 bits (543), Expect = 3e-59, Method: Composition-based stats.
Identities = 87/377 (23%), Positives = 145/377 (38%), Gaps = 61/377 (16%)
Query 69 HRGVTKRSLSPHRPRHSR---LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLS 125
+ V S + + R + + V++ E + P DP++ QQ+
Sbjct 80 YVAVEFPSRASTQARENFKRNVLEADDVEYAE-----DNATYEAIATPNDPQYGQQY--- 131
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF---DVNDQDPDP 182
+ +N +AAW Y G+ +S++D GI+ +H DL GN D S D D D DP
Sbjct 132 --APQQVNCEAAWDVTYGDPGVTISVVDQGIQYDHEDLEGNMDGSVSNYGDDFVDNDGDP 189
Query 183 QPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML----DGEVTDAVEAR 238
P N HGT G A NN G++ N + R L G +TD +A
Sbjct 190 YPVSASEN---HGTHVGGIAAGGTNNATGHAGIS-NCSLLSARALGDGGGGSLTDIADAI 245
Query 239 SLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGR 298
+ + + S G +T+ A GS+ V A+GNG
Sbjct 246 QWSAD-QGADVINMSLGGGGFSQTLSNACEYA------------YNQGSLLVAAAGNGYG 292
Query 299 EHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQ 358
S +++SS + + +S + GN V + +
Sbjct 293 NSVSYPAA----YDTVMAVSSLDEGETLSAFSN-LGPEIELAAPGGN------VLSSIPW 341
Query 359 KCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
++ +GTS ++P+ AG+ TL A+ NL+ +++ + T+ L+
Sbjct 342 DNYDTFSGTSMASPVVAGVAGFTLSAHPNLSNAELRSHLQNTAVDVGLS----------- 390
Query 419 KVSHSYGYGLLDAGAMV 435
S G+G +DAG V
Sbjct 391 --SEEQGHGRVDAGQAV 405
>sp|P29142|SUBT_GEOSE Subtilisin J OS=Geobacillus stearothermophilus
OX=1422 GN=aprJ PE=3 SV=1
Length=381
Score = 206 bits (525), Expect = 2e-58, Method: Composition-based stats.
Identities = 76/358 (21%), Positives = 135/358 (38%), Gaps = 68/358 (19%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+++P V ++E+ + V P Q + A +QGYTG
Sbjct 86 KELKKDPSVAYVEEDHIAHEYAQSV------PYGISQ----------IKAPALHSQGYTG 129
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
+ V+++D GI+ +HPDL N GASF ++ +P + + HGT AG +AA
Sbjct 130 SNVKVAVIDSGIDSSHPDL--NVRGGASFVPSETNP-------YQDGSSHGTHVAGTIAA 180
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNHIHIYSASWGPEDDGK 261
+ NN + +GV+ +A + V++LD + G+ N++ + + S G
Sbjct 181 L-NNSIGVLGVSPSASLYAVKVLDSTGSGQYSWIINGIEWAISNNMDVINMSLGGPSGST 239
Query 262 TVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSC---NCDGYTNSIYTLSIS 318
+ + ++A G + A+GN G S Y + T+++
Sbjct 240 ALK---TVVDKAVSS---------GIVVAAAAGNEGSSGSSSTVGYPAKYPS---TIAVG 284
Query 319 SATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGII 378
+ +S A S + + L ++ GTS + P AG
Sbjct 285 AVNSSNQRASFSSAGSELDVMAPGVS-------IQSTLPGGTYGAYNGTSMATPHVAGAA 337
Query 379 ALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
AL L + T ++ + T+ S YG GL++ A
Sbjct 338 ALILSKHPTWTNAQVRDRLESTATY--------------LGNSFYYGKGLINVQAAAQ 381
>sp|P00783|SUBT_BACSA Subtilisin amylosacchariticus OS=Bacillus
subtilis subsp. amylosacchariticus OX=1483 GN=apr PE=1 SV=2
Length=381
Score = 206 bits (524), Expect = 3e-58, Method: Composition-based stats.
Identities = 76/358 (21%), Positives = 135/358 (38%), Gaps = 68/358 (19%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+++P V ++E+ + V P Q + A +QGYTG
Sbjct 86 KELKKDPSVAYVEEDHIAHEYAQSV------PYGISQ----------IKAPALHSQGYTG 129
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
+ V+++D GI+ +HPDL N GASF ++ +P + + HGT AG +AA
Sbjct 130 SNVKVAVIDSGIDSSHPDL--NVRGGASFVPSETNP-------YQDGSSHGTHVAGTIAA 180
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNHIHIYSASWGPEDDGK 261
+ NN + +GV+ +A + V++LD + G+ N++ + + S G
Sbjct 181 L-NNSIGVLGVSPSASLYAVKVLDSTGSGQYSWIINGIEWAISNNMDVINMSLGGPSGST 239
Query 262 TVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSC---NCDGYTNSIYTLSIS 318
+ + ++A G + A+GN G S Y + T+++
Sbjct 240 ALK---TVVDKAVSS---------GIVVAAAAGNEGSSGSSSTVGYPAKYPS---TIAVG 284
Query 319 SATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGII 378
+ +S A S + + L ++ GTS + P AG
Sbjct 285 AVNSSNQRASFSSAGSELDVMAPGVS-------IQSTLPGGTYGAYNGTSMATPHVAGAA 337
Query 379 ALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
AL L + T ++ + T+ S YG GL++ A
Sbjct 338 ALILSKHPTWTNAQVRDRLESTATY--------------LGNSFYYGKGLINVQAAAQ 381
>sp|P23314|EXPR_XANCP Extracellular protease OS=Xanthomonas campestris
pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB
528 / LMG 568 / P 25) OX=190485 GN=XCC0851 PE=3 SV=1
Length=580
Score = 210 bits (535), Expect = 9e-58, Method: Composition-based stats.
Identities = 98/412 (24%), Positives = 151/412 (37%), Gaps = 74/412 (18%)
Query 70 RGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQE--------PTDPKFPQQ 121
V + +L P R R + + L +Q+A + V + P D + +Q
Sbjct 88 NSVRRLALGPELVRADRALDRAEAETLMRQLAADPNVQSVEVDQILHATLTPNDTRLSEQ 147
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF-------- 173
W G T LN++ AW + TG G VV+++D GI +H DL N G F
Sbjct 148 WAF-GTTNAGLNIRPAWDKA-TGSGTVVAVIDTGI-TSHADLNANILAGYDFISDATTAR 204
Query 174 DVNDQDPDPQPRYTQMNDN------------RHGTRCAGEVAAVANNGVCGVGVAYNARI 221
D N +D + N HGT AG VAAV NN G AY A++
Sbjct 205 DGNGRDSNAADEGDWYAANECGAGIPAASSSWHGTHVAGTVAAVTNNTTGVAGTAYGAKV 264
Query 222 GGVRML---DGEVTDAVEARSLG---------LNPNHIHIYSASWGPEDDGKTVDGPARL 269
VR+L G ++D +A N N + + S G T
Sbjct 265 VPVRVLGKCGGSLSDIADAIVWASGGTVSGIPANANPAEVINMSLGGGGSCST------- 317
Query 270 AEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY--TNSIYTLSISSATQFGNVP 327
+ G G+ V A+GN D+ N G N +++++ T G
Sbjct 318 ----TMQNAINGAVSRGTTVVVAAGN-----DASNVSGSLPANCANVIAVAATTSAGAKA 368
Query 328 WYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKN 387
YS + + S + TT S+ GTS ++P AG++AL
Sbjct 369 SYSNFGTGIDVSAPGSSILSTLNSGTTTPGSASYASYNGTSMASPHVAGVVALVQSVAPT 428
Query 388 -LTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALA 438
LT ++ L+ T++ + G +++A A V A
Sbjct 429 ALTPAAVETLLKNTARALPGACSGGCGAG------------IVNADAAVTAA 468
>sp|P29600|SUBS_LEDLE Subtilisin Savinase OS=Lederbergia lenta
OX=1467 PE=1 SV=1
Length=269
Score = 198 bits (504), Expect = 9e-57, Method: Composition-based stats.
Identities = 80/316 (25%), Positives = 124/316 (39%), Gaps = 57/316 (18%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
W +S V AA +G TG G+ V++LD GI HPDL N GASF +
Sbjct 6 WGISRV-----QAPAAHNRGLTGSGVKVAVLDTGIS-THPDL--NIRGGASFVPGE---- 53
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLG 241
+ + N HGT AG +AA+ NN + +GVA +A + V++L + +V + + G
Sbjct 54 ----PSTQDGNGHGTHVAGTIAAL-NNSIGVLGVAPSAELYAVKVLGASGSGSVSSIAQG 108
Query 242 L---NPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGR 298
L N +H+ + S G T++ G + V ASGN G
Sbjct 109 LEWAGNNGMHVANLSLGSPSPSATLEQ------------AVNSATSRGVLVVAASGNSGA 156
Query 299 EHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQ 358
S Y N+ +++ + Q N +S+ + V +
Sbjct 157 GSISYPAR-YANA---MAVGATDQNNNRASFSQYGAGLDIVAPG-------VNVQSTYPG 205
Query 359 KCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
S GTS + P AG AL + N +W ++Q N
Sbjct 206 STYASLNGTSMATPHVAGAAALVKQKNP--SWSNVQI------------RNHLKNTATSL 251
Query 419 KVSHSYGYGLLDAGAM 434
++ YG GL++A A
Sbjct 252 GSTNLYGSGLVNAEAA 267
>sp|I3R794|HLY_HALMT Halolysin OS=Haloferax mediterranei (strain
ATCC 33500 / DSM 1411 / JCM 8866 / NBRC 14739 / NCIMB 2177
/ R-4) OX=523841 GN=hly PE=1 SV=1
Length=519
Score = 205 bits (520), Expect = 3e-56, Method: Composition-based stats.
Identities = 88/474 (19%), Positives = 168/474 (35%), Gaps = 72/474 (15%)
Query 69 HRGVTKRSLSPHRPRH---SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLS 125
+ V S +P + R S + + +V++ E+ + DPK+ Q+
Sbjct 77 YAAVKFPSKAPKQARENFISAITKRDEVKYAEKNATH-----EALYTANDPKYGSQY--- 128
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPR 185
+ +N +AW + ++++D G++ +HPDL+ + D D D DP P
Sbjct 129 --APQQVNADSAWDTTLGSSSVKIAVVDQGVKYDHPDLSSQFGSNKGRDFVDNDGDPYP- 185
Query 186 YTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARS---LGL 242
++D HGT AG A +N G++ N+ + R L + + +
Sbjct 186 -DLLSDEYHGTHVAGIAAGTTDNNEGIGGIS-NSTLLSGRALSESGSGSTSDIADAIEWA 243
Query 243 NPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDS 302
+ + S G T+ A + GS+ V A+GN GR+ S
Sbjct 244 ADQGADVINLSLGGGGYSSTMKNAVSYATQ------------QGSLVVAAAGNDGRQSVS 291
Query 303 CNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTE 362
Y+ + ++S+ + YS S + +++
Sbjct 292 YPA-AYSECV---AVSALDPDETLASYSNYGSEIDLAAPGT------NVLSCWTTSTEYN 341
Query 363 SHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH 422
+GTS + P+ +G+ L L + NL+ D+++ + T+ L+ S
Sbjct 342 EISGTSMATPVVSGVAGLALAVH-NLSPADLRNHLKNTAVDIGLS-------------ST 387
Query 423 SYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHIT 482
G G +DA V T P + + + C+ + +
Sbjct 388 KQGSGRVDAANAV-------TTDPGDGGGGGGGGSKETTYDGTLSSSSDSNCVSHSWNYS 440
Query 483 RLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTT 536
Q + LS D ++ GT T R +D + W++ +T
Sbjct 441 SPS--QVVIDLSGPSSADFDLYATEGSGTCPT---TRSYD-----YRSWSYDST 484
>sp|P16588|PROA_VIBAL Alkaline serine exoprotease A OS=Vibrio
alginolyticus OX=663 GN=proA PE=3 SV=1
Length=534
Score = 203 bits (517), Expect = 1e-55, Method: Composition-based stats.
Identities = 74/340 (22%), Positives = 139/340 (41%), Gaps = 37/340 (11%)
Query 75 RSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNV 134
+LSP + + L+ +P+V ++EQ R D + W L + QR+L +
Sbjct 107 ANLSPEQLKD--LRSDPRVDYIEQD---RILSLDPIVSADANQTNAIWGLDRIDQRNLPL 161
Query 135 KAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRH 194
++ + G G+ ++D G+ H + G G +D D D D + N H
Sbjct 162 DNNYSANFDGTGVTAYVIDTGVNNAHVEFGGRSVSG--YDFVDNDAD------ASDCNGH 213
Query 195 GTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASW 254
GT AG + G GVA N + GVR+L + + G++ + + +
Sbjct 214 GTHVAGTI------GGSLYGVAKNVNLVGVRVLSCSGSGSTSGVIAGVD----WVAANAS 263
Query 255 GPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYT 314
GP ++ G +A ++ + Q G F+ A+GN D+CN
Sbjct 264 GPSVANMSLGGGQSVALDSAVQSAVQS----GVSFMLAAGNS--NADACNYSP-ARVATG 316
Query 315 LSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLA 374
+++ S T +S S ++ G+Q + + ++ +GTS + P
Sbjct 317 VTVGSTTSTDARSSFSNWGS--CVDVFAPGSQ-----IKSAWYDGGYKTISGTSMATPHV 369
Query 375 AGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATN 414
AG+ AL L+ N +++ ++ L+V + + + N
Sbjct 370 AGVAALYLQENSSVSPSQVEALIVSRASTGKVTDTRGSVN 409
>sp|P00780|SUBC_BACLI Subtilisin Carlsberg OS=Bacillus licheniformis
OX=1402 GN=subC PE=1 SV=2
Length=379
Score = 196 bits (497), Expect = 2e-54, Method: Composition-based stats.
Identities = 77/387 (20%), Positives = 144/387 (37%), Gaps = 57/387 (15%)
Query 62 GDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAK--RRTKRDVYQEPTDPKFP 119
DY + GV S+ + S + + Q + + AK + ++V +P D +
Sbjct 38 KDYIVGFKSGVKTASVKKDIIKESGGKVDKQFRIINAAKAKLDKEALKEVKNDP-DVAYV 96
Query 120 QQWYLSGVTQRD-------LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS 172
++ +++ + + AQG+ G + V++LD GI+ +HPDL N GAS
Sbjct 97 EEDHVAHALAQTVPYGIPLIKADKVQAQGFKGANVKVAVLDTGIQASHPDL--NVVGGAS 154
Query 173 FDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVT 232
F + + N HGT AG VAA+ +N +GVA + + V++L+ +
Sbjct 155 FVAGEAY--------NTDGNGHGTHVAGTVAAL-DNTTGVLGVAPSVSLYAVKVLNSSGS 205
Query 233 DAVEARSL---GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIF 289
+ N + + + S G + + + A+ +GV
Sbjct 206 GSYSGIVSGIEWATTNGMDVINMSLGGASGSTAMK---QAVDNAYAKGVVVVAAAGN--- 259
Query 290 VWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEK 349
SG+ G + Y + +++ + N +S + +G
Sbjct 260 ---SGSSGNTNTIGYPAKYDS---VIAVGAVDSNSNRASFSSVGAELEVMAPGAG----- 308
Query 350 QIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAN 409
V + + GTS ++P AG AL L + NL+ ++ N
Sbjct 309 --VYSTYPTNTYATLNGTSMASPHVAGAAALILSKHPNLSASQVR--------------N 352
Query 410 DWATNGVGRKVSHSYGYGLLDAGAMVA 436
++ S YG GL++ A
Sbjct 353 RLSSTATYLGSSFYYGKGLINVEAAAQ 379
>sp|Q45670|THES_BACSJ Thermophilic serine proteinase OS=Bacillus
sp. (strain AK1) OX=268807 PE=1 SV=1
Length=401
Score = 195 bits (496), Expect = 4e-54, Method: Composition-based stats.
Identities = 76/355 (21%), Positives = 127/355 (36%), Gaps = 60/355 (17%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L P V++ E P D + Y ++ AW
Sbjct 101 KALNNNPLVEYAEPNYLFNAA-----WTPNDTYYQGYQY----GPQNTYTDYAWDVTKGS 151
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G ++++D G++ HPDL G G +D D D DP M+ N HGT AG AA
Sbjct 152 SGQEIAVIDTGVDYTHPDLDGKVIKG--YDFVDNDYDP------MDLNNHGTHVAGIAAA 203
Query 205 VANNGVCGVGVAYNARIGGVRMLD----GEVTDAVEARSLGLNPNHIHIYSASWGPEDDG 260
NN G+A N RI VR LD G ++D +A + + + + S G +
Sbjct 204 ETNNATGIAGMAPNTRILAVRALDRNGSGTLSDIADAIIYAAD-SGAEVINLSLGCDCHT 262
Query 261 KTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA 320
T++ A GS+ V A+GN G + +++ +
Sbjct 263 TTLENAVNYA------------WNKGSVVVAAAGNNGSSTTFEPA----SYENVIAVGAV 306
Query 321 TQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIAL 380
Q+ + +S + IV+T + +GTS ++P AG+ AL
Sbjct 307 DQYDRLASFSNYGTWVDVVAPG------VDIVSTITGNR-YAYMSGTSMASPHVAGLAAL 359
Query 381 TLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMV 435
+N +++ + QT+ + YG +++ V
Sbjct 360 LASQGRN--NIEIRQAIEQTADKISGTGT-------------YFKYGRINSYNAV 399
>sp|P00782|SUBT_BACAM Subtilisin BPN' OS=Bacillus amyloliquefaciens
OX=1390 GN=apr PE=1 SV=1
Length=382
Score = 194 bits (492), Expect = 8e-54, Method: Composition-based stats.
Identities = 71/355 (20%), Positives = 127/355 (36%), Gaps = 62/355 (17%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
L+++P V ++E+ + V P Q + A +QGYTG
Sbjct 87 KELKKDPSVAYVEEDHVAHAYAQSV------PYGVSQ----------IKAPALHSQGYTG 130
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
+ V+++D GI+ +HPDL GAS ++ +P ++N HGT AG VAA
Sbjct 131 SNVKVAVIDSGIDSSHPDLK--VAGGASMVPSETNPF-------QDNNSHGTHVAGTVAA 181
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNHIHIYSASWGPEDDGK 261
+ NN + +GVA +A + V++L + + G+ N++ + + S G
Sbjct 182 L-NNSIGVLGVAPSASLYAVKVLGADGSGQYSWIINGIEWAIANNMDVINMSLGGPSGSA 240
Query 262 TVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
+ A + V+ G G Y + +++ +
Sbjct 241 ALKAAVDKAVASGVVVVAAAGNE---------GTSGSSSTVGYPGKYPS---VIAVGAVD 288
Query 322 QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALT 381
+S + + L ++ GTS ++P AG AL
Sbjct 289 SSNQRASFSSVGPELDVMAPGVS-------IQSTLPGNKYGAYNGTSMASPHVAGAAALI 341
Query 382 LEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
L + N T ++ + T+ S YG GL++ A
Sbjct 342 LSKHPNWTNTQVRSSLENTTTKLGD--------------SFYYGKGLINVQAAAQ 382
>sp|P07518|SUBT_BACPU Subtilisin OS=Bacillus pumilus OX=1408 GN=apr
PE=1 SV=1
Length=275
Score = 190 bits (483), Expect = 8e-54, Method: Composition-based stats.
Identities = 68/313 (22%), Positives = 121/313 (39%), Gaps = 52/313 (17%)
Query 130 RDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQM 189
+ A +QGYTG + V+++D GI+ +HPDL N GASF ++ +P
Sbjct 9 SQIKAPALHSQGYTGSNVKVAVIDSGIDSSHPDL--NVRGGASFVPSETNP-------YQ 59
Query 190 NDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNH 246
+ + HGT AG +AA+ NN + +GVA ++ + V++LD + G+ N+
Sbjct 60 DGSSHGTHVAGTIAAL-NNSIGVLGVAPSSALYAVKVLDSTGSGQYSWIINGIEWAISNN 118
Query 247 IHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSC--- 303
+ + + S G + + ++A G + A+GN G +
Sbjct 119 MDVINMSLGGPTGSTALK---TVVDKAVSS---------GIVVAAAAGNEGSSGSTSTVG 166
Query 304 NCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTES 363
Y + T+++ + +S A S + + L +
Sbjct 167 YPAKYPS---TIAVGAVNSANQRASFSSAGSELDVMAPGVS-------IQSTLPGGTYGA 216
Query 364 HTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHS 423
+ GTS + P AG AL L + T ++ + T+ S
Sbjct 217 YNGTSMATPHVAGAAALILSKHPTWTNAQVRDRLESTATY--------------LGSSFY 262
Query 424 YGYGLLDAGAMVA 436
YG GL++ A
Sbjct 263 YGKGLINVQAAAQ 275
>sp|P58371|SPM1_PYRO7 Subtilisin-like proteinase Spm1 OS=Pyricularia
oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507
GN=SPM1 PE=3 SV=1
Length=536
Score = 195 bits (494), Expect = 1e-52, Method: Composition-based stats.
Identities = 75/372 (20%), Positives = 137/372 (37%), Gaps = 45/372 (12%)
Query 34 WAVRIPGGPAVANSVARKHG-FLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHS--RLQRE 90
W ++ G RK G F ++ F H ++ G + H + +++R
Sbjct 63 WIQKVHGEREDERLELRKRGLFDSVNDAFTGLKHTYNVGSGFLGYAGHFDEETIEKVRRH 122
Query 91 PQVQWLEQQ-VAKRRTKRDVYQEPTDPKFPQ--QWYLSGVTQRDLNVKAAWAQ----GYT 143
P V+ +E+ + +V ++ +P + W LS V+ R+ + + +
Sbjct 123 PDVEAIERDTIVHTMRYEEVKKDECNPDLEKGAPWGLSRVSHRESLSFSTYNKYLYSAEG 182
Query 144 GHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVA 203
G G+ ++D G +H D G G + NDQD D N HGT C+G VA
Sbjct 183 GEGVDAYVIDTGTNIDHVDFEGRAHWGKTIPANDQDID---------GNGHGTHCSGTVA 233
Query 204 AVANNGVCGVGVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWGPEDD 259
GVA A++ V++L G ++D + + + +A G
Sbjct 234 GKK------YGVAKKAQVYAVKVLKSNGSGTMSDVIAGVDFAAKSHKAQVSAAKDGKRKG 287
Query 260 --GKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSI 317
G + + G F A+GN D+CN + ++
Sbjct 288 FKGSVANMSLGGGKTTLLDAAVNAAVDAGIHFAVAAGND--NADACNYSPAAAAKAV-TV 344
Query 318 SSATQFGNVPWYSE--ACSSTLATTYSSGNQNEKQIVTTDLRQKCT-ESHTGTSASAPLA 374
++ + ++S C+ A I +T + K + +GTS ++P
Sbjct 345 GASALDDSRAYFSNWGKCTDIFA--------PGLNIQSTWIGSKTAINTISGTSMASPHI 396
Query 375 AGIIALTLEANK 386
AG++A L
Sbjct 397 AGLLAYYLSLQP 408
>sp|Q9RYM8|SUB2_DEIRA Probable subtilase-type serine protease
DR_A0283 OS=Deinococcus radiodurans (strain ATCC 13939 / DSM
20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB
9279 / VKM B-1422 / R1) OX=243230 GN=DR_A0283 PE=1 SV=1
Length=728
Score = 198 bits (503), Expect = 2e-52, Method: Composition-based stats.
Identities = 99/457 (22%), Positives = 168/457 (37%), Gaps = 81/457 (18%)
Query 21 AADAQGQKVFT-NTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSP 79
+ ++ N V + G A+++A + G G++ +
Sbjct 56 VVTTKNGDMYVRNQLVVNLRG--HSADALADQLG----GRVLDQLPELDVALIELPQGKD 109
Query 80 HRPRHSRLQREPQVQW-----LEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNV 134
R L RE QV + +++Q+ RT +D + + L+
Sbjct 110 ARSVGVALMREGQVLYAAAQTVQRQIEPVRTAQDQLGAQAVNQVFDTLPQYALDSNHLHA 169
Query 135 KAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP--------DPQPRY 186
KAAW G+TG G+ V ++DD + +HPDL N+ G ++D D +
Sbjct 170 KAAWDAGFTGKGVKVGVIDDPSDVSHPDLRPNW-AGKAYDPATNTTYTTVQGWIDAIDGF 228
Query 187 TQMNDNR------HGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAVEARS 239
DN+ HGT A +AA A NG VGVA +++ + G + D + ARS
Sbjct 229 DGKVDNKVDPGIEHGTAVASTIAA-AKNGQGIVGVAPDSKFYTAAIFQPGFIGDYLVARS 287
Query 240 LGLNPN-HIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGR 298
+ N + + SWG G + L ++AF + + V ++GN R
Sbjct 288 VIWTVNQGAQVINNSWGGT-------GYSPLLKQAFDYALER-----DITVVVSAGNSYR 335
Query 299 E---------------HDSCNCDGYTNSIYTLSISSATQFGNV----PWYSEACSSTLAT 339
E N D S Y +S A +V P + A +
Sbjct 336 EEWRNPAQLPGVIASAALDINNDKAGFSTYGRHVSVAAPGVDVMLASPLFINADGTRKTG 395
Query 340 TYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQ 399
Y+ + Q++ +GTS S P +G+ A+ L A +L ++ L+ +
Sbjct 396 GYTKDGGSGYQLI------------SGTSFSGPYTSGVAAVILGAKPDLDPHQVRRLMEE 443
Query 400 TSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
T+ +N G GYGL+ +
Sbjct 444 TA------DGSVGSNKAG--FDRETGYGLIRMDKLAD 472
>sp|P11018|ISP1_BACSU Major intracellular serine protease OS=Bacillus
subtilis (strain 168) OX=224308 GN=isp PE=1 SV=2
Length=319
Score = 188 bits (477), Expect = 2e-52, Method: Composition-based stats.
Identities = 73/288 (25%), Positives = 114/288 (40%), Gaps = 40/288 (14%)
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND 191
+ WA+G G I V++LD G + +HPDL G +F D D +
Sbjct 29 IKAPEMWAKGVKGKNIKVAVLDTGCDTSHPDLKNQIIGGKNF----TDDDGGKEDAISDY 84
Query 192 NRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG-EVTDAVEARSLGLNP---NHI 247
N HGT AG +AA +NG GVA A + V++L G + E G+N +
Sbjct 85 NGHGTHVAGTIAANDSNG-GIAGVAPEASLLIVKVLGGENGSGQYEWIINGINYAVEQKV 143
Query 248 HIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGG----REHDSC 303
I S S G D + +EA V G + V A+GN G R +
Sbjct 144 DIISMSLGGPSDVPEL-------KEAVKNAVKN-----GVLVVCAAGNEGDGDERTEELS 191
Query 304 NCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTES 363
Y I S+S A + SE ++ + +N + + L K
Sbjct 192 YPAAYNEVIAVGSVSVAREL------SEFSNANKEIDLVAPGEN----ILSTLPNKKYGK 241
Query 364 HTGTSASAPLAAGIIALTLEANKN-----LTWRDMQHLVVQTSKPAHL 406
TGTS +AP +G +AL + L+ ++ +++ + P +
Sbjct 242 LTGTSMAAPHVSGALALIKSYEEESFQRKLSESEVFAQLIRRTLPLDI 289
>sp|W7K9M0|SUB1_PLAFO Subtilisin-like protease 1 OS=Plasmodium
falciparum (isolate NF54) OX=5843 GN=SUB1 PE=1 SV=1
Length=688
Score = 196 bits (498), Expect = 4e-52, Method: Composition-based stats.
Identities = 72/360 (20%), Positives = 128/360 (36%), Gaps = 66/360 (18%)
Query 114 TDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYD----- 168
D QW L +++ D + + ++D GI+ NHPDL N +
Sbjct 336 NDEFRNLQWGLD-LSRLDETQELINEHQVMST--RICVIDSGIDYNHPDLKDNIELNLKE 392
Query 169 --PGASFDVNDQD--------PDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYN 218
FD ++ M+DN HGT +G ++A+ NN + VGV N
Sbjct 393 LHGRKGFDDDNNGIVDDIYGANFVNNSGNPMDDNYHGTHVSGIISAIGNNNIGVVGVDVN 452
Query 219 ARIGGVRMLD----GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAF 274
+++ + LD G + D + ++ N H+ + S+ ++ + +
Sbjct 453 SKLIICKALDEHKLGRLGDMFKCLDYCISRN-AHMINGSFSFDEYSGIFNSSVEYLQR-- 509
Query 275 FRGVSQGRGGLGSIFVWASGNGGREHDSCN----CDGYTNSIY----------TLSISSA 320
G +F ++ N S CD N+ Y +S+++
Sbjct 510 ----------KGILFFVSASNCSHPKSSTPDIRKCDLSINAKYPPILSTVYDNVISVANL 559
Query 321 TQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIAL 380
+ N YS + +S + Y I +T GTS +AP A I +L
Sbjct 560 KKNDNNNHYSLSINSFYSNKYCQLAAPGTNIYST-APHNSYRKLNGTSMAAPHVAAIASL 618
Query 381 TLEANKNLTWRDMQHLVVQTSK--PAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALA 438
N +L+++ + ++ + P+ N WA G D V LA
Sbjct 619 IFSINPDLSYKKVIQILKDSIVYLPSLKNMVAWA--------------GYADINKAVNLA 664
>sp|Q8I0V0|SUB1_PLAF7 Subtilisin-like protease 1 OS=Plasmodium
falciparum (isolate 3D7) OX=36329 GN=SUB1 PE=1 SV=1
Length=688
Score = 196 bits (498), Expect = 4e-52, Method: Composition-based stats.
Identities = 72/360 (20%), Positives = 128/360 (36%), Gaps = 66/360 (18%)
Query 114 TDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYD----- 168
D QW L +++ D + + ++D GI+ NHPDL N +
Sbjct 336 NDEFRNLQWGLD-LSRLDETQELINEHQVMST--RICVIDSGIDYNHPDLKDNIELNLKE 392
Query 169 --PGASFDVNDQD--------PDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYN 218
FD ++ M+DN HGT +G ++A+ NN + VGV N
Sbjct 393 LHGRKGFDDDNNGIVDDIYGANFVNNSGNPMDDNYHGTHVSGIISAIGNNNIGVVGVDVN 452
Query 219 ARIGGVRMLD----GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAF 274
+++ + LD G + D + ++ N H+ + S+ ++ + +
Sbjct 453 SKLIICKALDEHKLGRLGDMFKCLDYCISRN-AHMINGSFSFDEYSGIFNSSVEYLQR-- 509
Query 275 FRGVSQGRGGLGSIFVWASGNGGREHDSCN----CDGYTNSIY----------TLSISSA 320
G +F ++ N S CD N+ Y +S+++
Sbjct 510 ----------KGILFFVSASNCSHPKSSTPDIRKCDLSINAKYPPILSTVYDNVISVANL 559
Query 321 TQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIAL 380
+ N YS + +S + Y I +T GTS +AP A I +L
Sbjct 560 KKNDNNNHYSLSINSFYSNKYCQLAAPGTNIYST-APHNSYRKLNGTSMAAPHVAAIASL 618
Query 381 TLEANKNLTWRDMQHLVVQTSK--PAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALA 438
N +L+++ + ++ + P+ N WA G D V LA
Sbjct 619 IFSINPDLSYKKVIQILKDSIVYLPSLKNMVAWA--------------GYADINKAVNLA 664
>sp|O61142|SUB1_PLAFA Subtilisin-like protease 1 OS=Plasmodium
falciparum OX=5833 GN=SUB1 PE=1 SV=1
Length=690
Score = 196 bits (498), Expect = 5e-52, Method: Composition-based stats.
Identities = 72/360 (20%), Positives = 128/360 (36%), Gaps = 66/360 (18%)
Query 114 TDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYD----- 168
D QW L +++ D + + ++D GI+ NHPDL N +
Sbjct 338 NDEFRNLQWGLD-LSRLDETQELINEHQVMST--RICVIDSGIDYNHPDLKDNIELNLKE 394
Query 169 --PGASFDVNDQD--------PDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYN 218
FD ++ M+DN HGT +G ++A+ NN + VGV N
Sbjct 395 LHGRKGFDDDNNGIVDDIYGANFVNNSGNPMDDNYHGTHVSGIISAIGNNNIGVVGVDVN 454
Query 219 ARIGGVRMLD----GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAF 274
+++ + LD G + D + ++ N H+ + S+ ++ + +
Sbjct 455 SKLIICKALDEHKLGRLGDMFKCLDYCISRN-AHMINGSFSFDEYSGIFNSSVEYLQR-- 511
Query 275 FRGVSQGRGGLGSIFVWASGNGGREHDSCN----CDGYTNSIY----------TLSISSA 320
G +F ++ N S CD N+ Y +S+++
Sbjct 512 ----------KGILFFVSASNCSHPKSSTPDIRKCDLSINAKYPPILSTVYDNVISVANL 561
Query 321 TQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIAL 380
+ N YS + +S + Y I +T GTS +AP A I +L
Sbjct 562 KKNDNNNHYSLSINSFYSNKYCQLAAPGTNIYST-APHNSYRKLNGTSMAAPHVAAIASL 620
Query 381 TLEANKNLTWRDMQHLVVQTSK--PAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALA 438
N +L+++ + ++ + P+ N WA G D V LA
Sbjct 621 IFSINPDLSYKKVIQILKDSIVYLPSLKNMVAWA--------------GYADINKAVNLA 666
>sp|P41363|ELYA_HALH5 Thermostable alkaline protease OS=Halalkalibacterium
halodurans (strain ATCC BAA-125 / DSM 18197 / FERM
7344 / JCM 9153 / C-125) OX=272558 GN=BH0855 PE=1 SV=2
Length=361
Score = 188 bits (476), Expect = 1e-51, Method: Composition-based stats.
Identities = 78/348 (22%), Positives = 138/348 (40%), Gaps = 69/348 (20%)
Query 90 EPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVV 149
+P V+ +E+ ++ W +S + N + A +G G+G V
Sbjct 78 DPNVKAIEKNAEVTISQTVP------------WGISFI-----NTQQAHNRGIFGNGARV 120
Query 150 SILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNG 209
++LD GI +HPDL GASF ++ + ++N HGT AG +AA+ NN
Sbjct 121 AVLDTGI-ASHPDL--RIAGGASFISSE--------PSYHDNNGHGTHVAGTIAAL-NNS 168
Query 210 VCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNHIHIYSASWGPEDDGKTVDGP 266
+ +GVA +A + V++LD + ++ + + G+ N++HI + S G T++
Sbjct 169 IGVLGVAPSADLYAVKVLDRNGSGSLASVAQGIEWAINNNMHIINMSLGSTSGSSTLELA 228
Query 267 ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNV 326
A A G + V A+GN GR+ + +++++ Q G
Sbjct 229 VNRANNA------------GILLVGAAGNTGRQGVNYPAR----YSGVMAVAAVDQNGQR 272
Query 327 PWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANK 386
+S + V + S +GTS + P AG+ AL
Sbjct 273 ASFSTYGPEIEISAPG-------VNVNSTYTGNRYVSLSGTSMATPHVAGVAALVKSRYP 325
Query 387 NLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAM 434
+ T ++ + QT+ + YG GL+ AG
Sbjct 326 SYTNNQIRQRINQTATYLGSPS--------------LYGNGLVHAGRA 359
>sp|P00781|SUBD_BACLI Subtilisin DY OS=Bacillus licheniformis
OX=1402 GN=apr PE=1 SV=1
Length=274
Score = 184 bits (467), Expect = 1e-51, Method: Composition-based stats.
Identities = 70/309 (23%), Positives = 113/309 (37%), Gaps = 49/309 (16%)
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND 191
+ AQGY G + V I+D GI +H DL GASF + +
Sbjct 11 IKADKVQAQGYKGANVKVGIIDTGIAASHTDLK--VVGGASFVSGESY--------NTDG 60
Query 192 NRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNHIH 248
N HGT AG VAA+ +N +GVA N + +++L+ + A G+ N +
Sbjct 61 NGHGTHVAGTVAAL-DNTTGVLGVAPNVSLYAIKVLNSSGSGTYSAIVSGIEWATQNGLD 119
Query 249 IYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY 308
+ + S G + + ++A+ G + V A+GN G S N GY
Sbjct 120 VINMSLGGPSGSTALK---QAVDKAY---------ASGIVVVAAAGNSGSSG-SQNTIGY 166
Query 309 -TNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGT 367
+++ + N +S + L + V + S GT
Sbjct 167 PAKYDSVIAVGAVDSNKNRASFSSV-GAELEVMAPGVS------VYSTYPSNTYTSLNGT 219
Query 368 SASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYG 427
S ++P AG AL L L+ ++ N ++ S YG G
Sbjct 220 SMASPHVAGAAALILSKYPTLSASQVR--------------NRLSSTATNLGDSFYYGKG 265
Query 428 LLDAGAMVA 436
L++ A
Sbjct 266 LINVEAAAQ 274
>sp|P29139|ISP_PAEPO Intracellular serine protease OS=Paenibacillus
polymyxa OX=1406 GN=isp PE=1 SV=1
Length=326
Score = 184 bits (466), Expect = 9e-51, Method: Composition-based stats.
Identities = 66/295 (22%), Positives = 109/295 (37%), Gaps = 31/295 (11%)
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND 191
+ A W Q G G+ V++LD G + +HPDL G +F D D +
Sbjct 29 IQAPAVWNQT-RGRGVKVAVLDTGCDADHPDLKARIIGGRNF----TDDDEGDPEIFKDY 83
Query 192 NRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNP---NHIH 248
N HGT AG +AA N VGVA A + +++L+ + + + G+ +
Sbjct 84 NGHGTHVAGTIAATENEN-GVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVD 142
Query 249 IYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY 308
I S S G +D + EA + V+ + + A+GN G D + GY
Sbjct 143 IISMSLGGPEDVPELH-------EAVKKAVASQ-----ILVMCAAGNEGDGDDRTDELGY 190
Query 309 TNSIY-TLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGT 367
+S+ + + +S + + + + + + +GT
Sbjct 191 PGCYNEVISVGAINFDRHASEFSNSNNEVDLVAPGED-------ILSTVPGGKYATFSGT 243
Query 368 SASAPLAAGIIALTLEANKNLTWRDMQ--HLVVQTSKPAHLNANDWATNGVGRKV 420
S + P AG +AL + RD+ L Q K N G G
Sbjct 244 SMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPKMEGNGLLY 298
>sp|Q8IHZ5|SUB2_PLAF7 Subtilisin-like protease 2 OS=Plasmodium
falciparum (isolate 3D7) OX=36329 GN=SUB2 PE=1 SV=1
Length=1341
Score = 196 bits (497), Expect = 2e-50, Method: Composition-based stats.
Identities = 92/366 (25%), Positives = 138/366 (38%), Gaps = 53/366 (14%)
Query 85 SRLQREPQVQWLEQQVAKRRT--KRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAW-AQG 141
L EP + + ++ +KR K + P + + W LS + V AW G
Sbjct 688 KFLNIEPLILFAKKLNSKRSNIEKEILNFLPKELRDYSTWNLSIIR-----VFNAWFLAG 742
Query 142 YTGHGIVVSILDDGIEKNHPDLAGN-YDPGASFDVNDQDPDPQPRYTQMNDN-----RHG 195
Y + V ++D G + NH DL GN Y P N++ Q Y M N HG
Sbjct 743 YGNKNVKVCVVDSGADINHVDLNGNLYIPE----YNEKYEMTQDFYNFMVKNPTDASGHG 798
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTD----AVEARSLGLNPNHIHIYS 251
T G + VAN+ + VGVA N + +R +DG+ A++A ++ + N I +
Sbjct 799 THVTGIIGGVAND-LGVVGVAPNITLISLRFIDGKKYGGSFHAIKALNVCI-LNKAPIIN 856
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
ASWG D LA E G GS+ + ASGN ++D T +
Sbjct 857 ASWG----SSHFDVNLHLAVERLKY----TLNGKGSVLIAASGNKSNDNDISPLYPATFT 908
Query 312 I----YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGT 367
SIS + Y LA I +T + + TGT
Sbjct 909 FPHVYSVASISRNFEISPFSNYGHKSVHILA--------PGHHIYST-IPNNSYKIFTGT 959
Query 368 SASAPLAAGIIALTLEANKN----LTWRDMQHLVVQTSKPA----HLNANDWATNGVGRK 419
S +AP G+ AL N ++ ++ +TS ND N G
Sbjct 960 SMAAPHVCGVSALVYSVCYNQGFIPQAEEVLDILTRTSIKIISTKKRTINDSLVNAEGAV 1019
Query 420 VSHSYG 425
++ G
Sbjct 1020 LTTLLG 1025
>sp|O97364|SUB2_PLAFA Subtilisin-like protease 2 OS=Plasmodium
falciparum OX=5833 GN=SUB2 PE=1 SV=1
Length=1342
Score = 195 bits (494), Expect = 3e-50, Method: Composition-based stats.
Identities = 91/366 (25%), Positives = 137/366 (37%), Gaps = 53/366 (14%)
Query 85 SRLQREPQVQWLEQQVAKRRT--KRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAW-AQG 141
L EP + + ++ +KR K + P + + W LS + V AW G
Sbjct 689 KFLNIEPLILFAKKLNSKRSNIEKEILNFLPKELRDYSTWNLSIIR-----VFNAWFLAG 743
Query 142 YTGHGIVVSILDDGIEKNHPDLAGN-YDPGASFDVNDQDPDPQPRYTQMNDN-----RHG 195
Y + V ++D G + H DL GN Y P N++ Q Y M N HG
Sbjct 744 YGNKNVKVCVVDSGADIKHVDLNGNLYIPE----YNEKYEMTQDFYNFMVKNPTDASGHG 799
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTD----AVEARSLGLNPNHIHIYS 251
T G + VAN+ + VGVA N + +R +DG+ A++A ++ + N I +
Sbjct 800 THVTGIIGGVAND-LGVVGVAPNITLISLRFIDGKKYGGSFHAIKALNVCI-LNKAPIIN 857
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
ASWG D LA E G GS+ + ASGN ++D T +
Sbjct 858 ASWG----SSHFDVNLHLAVERLKY----TLNGKGSVLIAASGNKSNDNDISPLYPATFT 909
Query 312 I----YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGT 367
SIS + Y LA I +T + + TGT
Sbjct 910 FPHVYSVASISRNFEISPFSNYGHKSVHILA--------PGHHIYST-IPNNSYKIFTGT 960
Query 368 SASAPLAAGIIALTLEANKN----LTWRDMQHLVVQTSKPA----HLNANDWATNGVGRK 419
S +AP G+ AL N ++ ++ +TS ND N G
Sbjct 961 SMAAPHVCGVSALVYSVCYNQGFIPQAEEVLDILTRTSIKIISTKKRTINDSLVNAEGAV 1020
Query 420 VSHSYG 425
++ G
Sbjct 1021 LTTLLG 1026
>sp|O31788|APRX_BACSU Serine protease AprX OS=Bacillus subtilis
(strain 168) OX=224308 GN=aprX PE=1 SV=1
Length=442
Score = 185 bits (470), Expect = 4e-50, Method: Composition-based stats.
Identities = 78/334 (23%), Positives = 127/334 (38%), Gaps = 72/334 (22%)
Query 140 QGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
Q TG G+ V+++D GI HPDL G A D+ +Q +P +DN HGT CA
Sbjct 142 QTLTGKGVTVAVVDTGI-YPHPDLEGRIIGFA--DMVNQKTEPY------DDNGHGTHCA 192
Query 200 GEVAAVANNGVCGV-GVAYNARIGGVRML----DGEVTDAVEARSLGLNPN------HIH 248
G+VA+ + G A A + GV++L G + D +E + N I
Sbjct 193 GDVASSGASSSGQYRGPAPEANLIGVKVLNKQGSGTLADIIEGVEWCIQYNEDNPDEPID 252
Query 249 IYSASWGPED---DGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNC 305
I S S G + D + D R EEA+ G + A+GN G + +
Sbjct 253 IMSMSLGGDALRYDHEQEDPLVRAVEEAW---------SAGIVVCVAAGNSGPDSQTIAS 303
Query 306 DGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLR-------- 357
G S +++ + + +S + + + + I+ +
Sbjct 304 PGV--SEKVITVGALDDNNTASSDDDTVASFSSRGPTVYGKEKPDILAPGVNIISLRSPN 361
Query 358 ------------QKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAH 405
+ +GTS + P+ AGI AL L+ N +LT +++ L+
Sbjct 362 SYIDKLQKSSRVGSQYFTMSGTSMATPICAGIAALILQQNPDLTPDEVKELL-------- 413
Query 406 LNANDWATNGVGRKVSHS---YGYGLLDAGAMVA 436
NG + YG G ++A V
Sbjct 414 -------KNGTDKWKDEDPNIYGAGAVNAENSVP 440
>sp|P04072|THET_THEVU Thermitase OS=Thermoactinomyces vulgaris
OX=2026 PE=1 SV=1
Length=279
Score = 180 bits (455), Expect = 9e-50, Method: Composition-based stats.
Identities = 82/327 (25%), Positives = 121/327 (37%), Gaps = 54/327 (17%)
Query 113 PTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS 172
P DP F + Y + + AW G G ++I+D G++ NHPDLAG G
Sbjct 3 PNDPYFSSRQY----GPQKIQAPQAWDIA-EGSGAKIAIVDTGVQSNHPDLAGKVVGG-- 55
Query 173 FDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVT 232
+D D D PQ N N HGT CAG AAV NN G A A I VR+LD +
Sbjct 56 WDFVDNDSTPQ------NGNGHGTHCAGIAAAVTNNSTGIAGTAPKASILAVRVLDNSGS 109
Query 233 DAVEARSLGL---NPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIF 289
A + G+ + S S G + A GS+
Sbjct 110 GTWTAVANGITYAADQGAKVISLSLGGTVGNSGLQQAVNYA------------WNKGSVV 157
Query 290 VWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEK 349
V A+GN G + Y+N+I +++S Q N +S S S
Sbjct 158 VAAAGNAGNTAPNYPAY-YSNAI---AVASTDQNDNKSSFSTYGSVVDVAAPGS------ 207
Query 350 QIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAN 409
+ + S +GTS + P AG+ L ++ + +++ + T+
Sbjct 208 -WIYSTYPTSTYASLSGTSMATPHVAGVAGLLASQGRSAS--NIRAAIENTADKISGTGT 264
Query 410 DWATNGVGRKVSHSYGYGLLDAGAMVA 436
WA G ++A V
Sbjct 265 YWAK-------------GRVNAYKAVQ 278
>sp|P29138|CUDP_METAN Cuticle-degrading protease OS=Metarhizium
anisopliae OX=5530 GN=PR1 PE=1 SV=1
Length=388
Score = 177 bits (448), Expect = 1e-47, Method: Composition-based stats.
Identities = 81/433 (19%), Positives = 145/433 (33%), Gaps = 84/433 (19%)
Query 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFT--------NTWAVRIPGG------PAVAN 46
M L L + A + A+ +FT + + V+ +
Sbjct 1 MHLSALLTLLPAVLAAPATIGRRAEPAPLFTPQAESIIADKYIVKFKDDIARIATDDTVS 60
Query 47 SVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTK 106
++ K F ++ +H + +TK L L+ P V ++E+ R +
Sbjct 61 ALTSKADF-----VYEHAFHGFAGSLTKEELK-------MLREHPGVDFIEKDAVMRIS- 107
Query 107 RDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
+ ++ P W L ++ R G G V I+D GIE +HP+ G
Sbjct 108 -GITEQSGAP-----WGLGRISHRSKGSTTYRYDDSAGQGTCVYIIDTGIEASHPEFEGR 161
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
SF + + HGT CAG + G GVA A++ GV++
Sbjct 162 ATFLKSFISGQN----------TDGHGHGTHCAGTI------GSKTYGVAKKAKLYGVKV 205
Query 227 LDGEVTDAVEARSLGLN-----------PNHIHIYSASWGPEDDGKTVDGPARLAEEAFF 275
LD + + + G++ PN I S S G G A L
Sbjct 206 LDNQGSGSYSGIISGMDYVAQDSKTRGCPNGA-IASMSLGGGYSASVNQGAAALVNS--- 261
Query 276 RGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSS 335
G A+GN R+ + + ++ ++ ++ + + +S
Sbjct 262 ----------GVFLAVAAGNDNRDAQNTSPASEPSAC---TVGASAENDSRSSFSNYGRV 308
Query 336 TLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQH 395
S +++T + + T S +GTS + P AG+ A T +
Sbjct 309 VDIFAPGS------NVLSTWIVGR-TNSISGTSMATPHIAGLAAYLSALQGKTTPAALCK 361
Query 396 LVVQTSKPAHLNA 408
+ T+ L
Sbjct 362 KIQDTATKNVLTG 374
>sp|P80146|SEPR_THESR Extracellular serine proteinase OS=Thermus
sp. (strain Rt41A) OX=32063 PE=1 SV=3
Length=410
Score = 175 bits (443), Expect = 1e-46, Method: Composition-based stats.
Identities = 71/338 (21%), Positives = 125/338 (37%), Gaps = 54/338 (16%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
+RL+++P+V ++E R + P W L + QR L + + TG
Sbjct 112 ARLRQDPRVAYIEADQEVRAFA---------VQSPATWGLDRIDQRTLPLDGRYTYTATG 162
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G+ ++D GI +H + G G +D P + + N HGT AG +
Sbjct 163 AGVHAYVVDTGILLSHQEFTGRI--GKGYD------AITPGGSAQDCNGHGTHVAGTIGG 214
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNHIH--IYSASWGPEDD 259
GVA + VR+LD + + + GL+ NH+ + + S G
Sbjct 215 TT------YGVAKGVTLHPVRVLDCNGSGSNSSVIAGLDWVTQNHVKPAVINMSLG---- 264
Query 260 GKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISS 319
G + + A + G V A+GN R+ + T +I ++ +
Sbjct 265 ----GGASTALDTAVMNAI-----NAGVTVVVAAGNDNRDACFYSPARVTAAI---TVGA 312
Query 320 ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC--TESHTGTSASAPLAAGI 377
T +S ++ G Q +T+ T + +GTS + P G
Sbjct 313 TTSTDYRASFSNYG--RCLDLFAPG-----QSITSAWYTSSTATNTISGTSMATPHVTGA 365
Query 378 IALTLEANKNLTWRDMQHLVVQTSKP-AHLNANDWATN 414
AL L+ T + ++ + P NA ++ N
Sbjct 366 AALYLQWYPTATPSQVASALLYYATPNVVKNAGRYSPN 403
>sp|Q9Y008|SUB2_PLAFP Subtilisin-like protease 2 OS=Plasmodium
falciparum (isolate Palo Alto / Uganda) OX=57270 GN=SUB2 PE=1
SV=1
Length=1337
Score = 183 bits (465), Expect = 2e-46, Method: Composition-based stats.
Identities = 88/366 (24%), Positives = 135/366 (37%), Gaps = 53/366 (14%)
Query 85 SRLQREPQVQWLEQQVAKRRT--KRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAW-AQG 141
L EP + + ++ +KR K + P + + W LS + V AW G
Sbjct 684 KFLNIEPLILFAKKLNSKRSNIEKEILNFLPKELRDYSTWNLSIIR-----VFNAWFLAG 738
Query 142 YTGHGIVVSILDDGIEKNHPDLAGN-YDPGASFDVNDQDPDPQPRYTQMNDN-----RHG 195
Y + V ++D G + N DL GN Y P N++ Q Y M HG
Sbjct 739 YGNKNVKVCVVDSGADINRVDLNGNLYIPE----YNEKYEMTQDFYNFMVKKSYRCLGHG 794
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTD----AVEARSLGLNPNHIHIYS 251
+ G + VAN+ + VGVA N + +R +DG+ A++A ++ + N I +
Sbjct 795 SHVTGIIGGVAND-LGVVGVAPNITLISLRFIDGKKYGGSFHAIKALNVCI-LNKAPIIN 852
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
ASWG D L E G GS+ + ASGN ++D T +
Sbjct 853 ASWG----SSHFDVNLHLTVERLKY----TLNGKGSVLIAASGNKSNDNDISPLYPATFT 904
Query 312 I----YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGT 367
SIS + Y LA I +T + + TGT
Sbjct 905 FPHVYSVASISRNFEISPFSNYGYKSVHILA--------PGHHIYST-IPNNSYKIFTGT 955
Query 368 SASAPLAAGIIALTLEANKN----LTWRDMQHLVVQTSKPA----HLNANDWATNGVGRK 419
S +AP G+ AL N ++ ++ +TS ND N G
Sbjct 956 SMAAPHVCGVSALVYSVCYNQGFIPQAEEVLDILTRTSIKIISTKKRTINDSLVNAEGAV 1015
Query 420 VSHSYG 425
++ G
Sbjct 1016 LTTLLG 1021
>sp|L8FSM5|SUB2_PSED2 Subtilisin-like protease 2 OS=Pseudogymnoascus
destructans (strain ATCC MYA-4855 / 20631-21) OX=658429
GN=SP2 PE=1 SV=1
Length=400
Score = 173 bits (437), Expect = 5e-46, Method: Composition-based stats.
Identities = 73/396 (18%), Positives = 128/396 (32%), Gaps = 65/396 (16%)
Query 9 WVVAATGTLVLLAADAQ-----------GQKVFTNTWAVRIPGGPAVANSVAR----KHG 53
+ A L L+AA + Q + +++ V G A+ + H
Sbjct 7 LIALAACFLPLIAAAPEEAQHAKIRSPGAQDIILDSYIVVFNKGVNDADIESEFASVSHI 66
Query 54 FLNLGQIFGDYYHFWH-RGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQE 112
H ++ G + + P V W+E+ V
Sbjct 67 LSKRRPAHKGVGHKYNITGFKGYQIETDTGSIGEIAASPLVAWIERD-------GKVQAN 119
Query 113 PTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS 172
+ + W L ++ + + G G V ++D GI H + G GA+
Sbjct 120 ALETRSGATWGLGRISHKATGSNSYVYDSSAGSGSTVYVVDSGIYIEHSEFEGRAKWGAN 179
Query 173 FDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVT 232
+ D D +N HGT CAG +A GVA A + V++LDG+ +
Sbjct 180 YISGSPDTD---------ENGHGTHCAGTIAGAT------YGVASKANLVAVKVLDGDGS 224
Query 233 DAVEARSLGLN------PNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLG 286
+ G+N + + S S G A + G
Sbjct 225 GSNSGVIAGINFVGQNGKDGKSVLSMSLGGSY-------------SAALNSAVESTISNG 271
Query 287 SIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ 346
V A+GN G + + + N+I ++ S + Y S L +
Sbjct 272 VTVVVAAGNDGADASNYSPASAKNAITVGAVDSTDTRADFSNY----GSVLDVFAPGVDV 327
Query 347 NEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTL 382
I + + + + +GTS + P AG+ A +
Sbjct 328 KSAWIGS----KSASNTISGTSMATPHVAGLAAYLI 359
>sp|Q5RLZ1|NEP_NATMA Halolysin-like extracellular serine protease
Nep OS=Natrialba magadii OX=13769 GN=nep PE=1 SV=2
Length=541
Score = 176 bits (445), Expect = 6e-46, Method: Composition-based stats.
Identities = 82/376 (22%), Positives = 145/376 (39%), Gaps = 59/376 (16%)
Query 69 HRGVTKRSLSPHRPRHSR---LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLS 125
+ V S + + R + + +E +++ E + + P DP + QQ+
Sbjct 80 YVAVKFPSNAAEQARENFKRNVLQEDDIEYAE-----DNATYETLEVPNDPMYGQQY--- 131
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS---FDVNDQDPDP 182
+ +N + AWA+ Y +V+S++D GI+ +H +LA N D S +D D D DP
Sbjct 132 --APQQVNCEGAWAETYGDDDVVISVVDQGIQYDHENLAENMDGSVSDYGYDFVDDDGDP 189
Query 183 QPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM---LDGEVTDAVEARS 239
P N HGT G A NN G++ N + R G +
Sbjct 190 YPVSAGEN---HGTHVGGIAAGGTNNDTGHAGIS-NCSMLSARALGDGGGGSLSDIADAI 245
Query 240 LGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGRE 299
I + S G +T+D + A + G++ V A+GN
Sbjct 246 QWSADQGADIINMSLGGGGFSETLDNACQYAYD------------EGTLLVAAAGNDHGG 293
Query 300 HDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQK 359
S +++SS + + +S + GN V + +
Sbjct 294 SVSYPAA----YDSVMAVSSLDEGETLSSFSNV-GPEIELAAPGGN------VLSAVNWD 342
Query 360 CTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRK 419
+S +GTS ++P+AAG+ L L A+ L+ +++ + T+ L+ ++
Sbjct 343 DYDSLSGTSMASPVAAGVAGLALSAHPGLSNDELRDHLHDTAVDIGLSDDE--------- 393
Query 420 VSHSYGYGLLDAGAMV 435
GYG +DA V
Sbjct 394 ----QGYGRVDAELAV 405
>sp|L8G6I7|SUB1_PSED2 Subtilisin-like protease 1 OS=Pseudogymnoascus
destructans (strain ATCC MYA-4855 / 20631-21) OX=658429
GN=SP1 PE=1 SV=1
Length=400
Score = 172 bits (435), Expect = 1e-45, Method: Composition-based stats.
Identities = 78/395 (20%), Positives = 133/395 (34%), Gaps = 63/395 (16%)
Query 9 WVVAATGTLVLLAA-----------DAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNL 57
+ A L L+AA + Q + +++ V G A+ + F ++
Sbjct 7 LIALAACFLPLIAAAPVEAQHAKIRSPRAQDIIPDSYIVVFNKGVNDADIESE---FSSV 63
Query 58 GQIFGDYYHFWHRGVTKR---------SLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRD 108
+I H+GV + + + P V W+E
Sbjct 64 SRILSKRRS-AHKGVGHKYNITGFKGYQIETDTGSIGEIAASPLVAWIEMD-------GK 115
Query 109 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYD 168
V + + W L ++ + + G G G V +LD GI H + G
Sbjct 116 VQANALETRSGATWGLGRISHKATGSNSYIYDGSAGSGSTVYVLDTGIYIEHSEFEGRAK 175
Query 169 PGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD 228
GA++ D D +N HGT CAG +A GVA A + V++LD
Sbjct 176 WGANYISGSPDTD---------ENGHGTHCAGTIAGAT------YGVASKANLVAVKVLD 220
Query 229 GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
+ A A G+N + +D + R A + G
Sbjct 221 RDGFGATSATIAGINFVGQN-------GKDGKSVISMSLRGHYSAAVNSAVESTVSNGVT 273
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNE 348
V A+GN G + + + N+I S+ S + Y + ++ G
Sbjct 274 IVVAAGNDGDDASNYSPASAKNAITVGSVDSTDTRASSSNYGS-----VVDIFAPGV--- 325
Query 349 KQIVTTDLRQKCTESH-TGTSASAPLAAGIIALTL 382
+ + + K S +GTS + P AG+ A +
Sbjct 326 -NVKSASIGGKSAFSIKSGTSMATPHVAGLAAYLI 359
>sp|D4DKQ4|SUB8_TRIVH Subtilisin-like protease 8 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB8 PE=3 SV=1
Length=490
Score = 173 bits (437), Expect = 3e-45, Method: Composition-based stats.
Identities = 72/391 (18%), Positives = 139/391 (36%), Gaps = 61/391 (16%)
Query 44 VANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVA 101
+ + +++ F + F H + S H +++R P V+++E+
Sbjct 72 ESKRMKKRNQFTFKNEAFDGLKHTFDFAGGFLGYSGHFDEEVIEQVRRHPDVEYIERD-- 129
Query 102 KRRTKRDVYQEPTDPKFPQQWYLSGVTQRD-LNV---KAAWAQGYTGHGIVVSILDDGIE 157
+V+ + W L+ ++ RD LN G G+ ++D G
Sbjct 130 -----SEVHTLKAATENGAPWGLARISHRDKLNFGTFNKYIYASQGGEGVDAYVIDTGTN 184
Query 158 KNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAY 217
+H D G G + D D D N HGT C+G +A GVA
Sbjct 185 IDHVDFEGRASWGKTIPQGDDDVD---------GNGHGTHCSGTIAGKK------YGVAK 229
Query 218 NARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWG------PEDDGKTVDGPA 267
A + V++L G ++D V+ + + A G ++ G
Sbjct 230 KANVYAVKVLRTSGSGTMSDVVKGVQWAAESHLKSVAEAKKGNRKGFKGSVANMSLGGGK 289
Query 268 RLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVP 327
+ + V +G F A+GN + + + G NSI ++ ++T
Sbjct 290 SVTLDR----VVDQAVAVGMHFAVAAGNDNADACNYSPAGSKNSI---TVGASTLADERA 342
Query 328 WYSEACSSTLATTYSSGNQNEKQIVTTDLRQK-CTESHTGTSASAPLAAGIIALTLEANK 386
++S ++ G I +T + K + +GTS ++P G++A L
Sbjct 343 YFSNFGK--CTDIFAPG----LNIQSTWIGSKHAVNTISGTSMASPHICGLLAYFLSLQP 396
Query 387 ---------NLTWRDMQHLVVQTSKPAHLNA 408
+T +M+ ++ + L+
Sbjct 397 ASDSAFAVAEITPAEMKENMISIASKDLLSD 427
>sp|Q68GV9|ALP_LECPS Alkaline serine protease ver112 OS=Lecanicillium
psalliotae OX=73499 PE=1 SV=1
Length=382
Score = 169 bits (427), Expect = 9e-45, Method: Composition-based stats.
Identities = 67/343 (20%), Positives = 110/343 (32%), Gaps = 57/343 (17%)
Query 50 RKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDV 109
K G +N + + S + RL+R+P V+ +EQ
Sbjct 47 AKFGIMNAKSKIPGIERVYENVLNGFSATLSNEELERLRRDPDVESIEQDAIFSINAITQ 106
Query 110 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDP 169
Q T W L+ ++ R A G G V ++D G+E HPD G
Sbjct 107 QQGAT-------WGLTRISHRARGSTAYAYDTSAGAGACVYVIDTGVEDTHPDFEGRAKQ 159
Query 170 GASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG 229
S+ +D + HGT CAG + G GVA I GV++LD
Sbjct 160 IKSYASTARD-----------GHGHGTHCAGTI------GSKTWGVAKKVSIFGVKVLDD 202
Query 230 EVTDAVEARSLGLNPNHIH----------IYSASWGPEDDGKTVDGPARLAEEAFFRGVS 279
+ ++ G++ + S S G ARL
Sbjct 203 SGSGSLSNIVAGMDFVASDRQSRNCPRRTVASMSLGGGYSAALNQAAARL---------- 252
Query 280 QGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLAT 339
G A+GN R+ + + + ++ + +S
Sbjct 253 ---QSSGVFVAVAAGNDNRDAANTSP---ASEPTVCTVGATDSNDVRSTFSNYGRVVDIF 306
Query 340 TYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTL 382
+ I +T + + T + +GTS + P AG+ A
Sbjct 307 APGT------SITSTWIGGR-TNTISGTSMATPHIAGLAAYLF 342
>sp|D4AX50|SUB8_ARTBC Subtilisin-like protease 8 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB8
PE=3 SV=1
Length=490
Score = 171 bits (434), Expect = 9e-45, Method: Composition-based stats.
Identities = 72/387 (19%), Positives = 137/387 (35%), Gaps = 53/387 (14%)
Query 44 VANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVA 101
+ + +++ F + F H + S H +++R P V+++E+
Sbjct 72 ESKRMKKRNQFTFKNEAFDGLKHTFDFAGGFLGYSGHFDEEVIEQVRRHPDVEYIERD-- 129
Query 102 KRRTKRDVYQEPTDPKFPQQWYLSGVTQRD-LNV---KAAWAQGYTGHGIVVSILDDGIE 157
+V+ + W L+ ++ RD LN G G+ ++D G
Sbjct 130 -----SEVHTLKAATENGAPWGLARISHRDKLNFGTFNKYIYASQGGEGVDAYVIDTGTN 184
Query 158 KNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAY 217
+H D G G + D D D N HGT C+G +A GVA
Sbjct 185 IDHVDFEGRASWGKTIPQGDDDVD---------GNGHGTHCSGTIAGKK------YGVAK 229
Query 218 NARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWGPEDD--GKTVDGPARLAE 271
A + V++L G ++D V+ + + A G G + +
Sbjct 230 KANVYAVKVLRTSGSGTMSDVVKGVQWAAESHLKSVGEAKKGNRKGFKGSVANMSLGGGK 289
Query 272 EAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSE 331
V +G F A+GN + + + G NSI ++ ++T ++S
Sbjct 290 SVTLDRVVDQAVAVGMHFAVAAGNDNADACNYSPAGSKNSI---TVGASTLADERAYFSN 346
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQK-CTESHTGTSASAPLAAGIIALTLEANK---- 386
++ G I +T + K + +GTS ++P G++A L
Sbjct 347 FGK--CTDIFAPG----LNIQSTWIGSKHAVNTISGTSMASPHICGLLAYFLSLQPASDS 400
Query 387 -----NLTWRDMQHLVVQTSKPAHLNA 408
+T +M+ ++ + L+
Sbjct 401 AFAVAEITPAEMKDNMISIASKDLLSD 427
>sp|Q9P8G3|PEN18_PENRB Subtilisin-like serine protease Pen ch
18.0101 OS=Penicillium rubens OX=1108849 PE=1 SV=1
Length=494
Score = 171 bits (433), Expect = 1e-44, Method: Composition-based stats.
Identities = 72/390 (18%), Positives = 136/390 (35%), Gaps = 80/390 (21%)
Query 52 HGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDV 109
GF + F H +H + + H +++R P V ++E+ R
Sbjct 83 FGFDF--EAFMGLKHTFHIAGSLLGYAGHFHEDVIEQIRRHPDVDYIEKDSEVRTMSEGS 140
Query 110 YQEPTDPKFPQQWYLSGVTQRDL----NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG 165
++ W L+ ++ R+ N G G+ ++D G H D G
Sbjct 141 VEK------NAPWGLARISHRESLSFGNFNKYLYAEEGGEGVDAYVIDTGANVKHVDFEG 194
Query 166 NYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVR 225
+ G + D D D N HGT C+G +A GVA A + V+
Sbjct 195 RANWGKTIPQGDADED---------GNGHGTHCSGTIAGKK------FGVAKKANVYAVK 239
Query 226 ML----DGEVTDAVEARSLGLNPN-----------HIHIYSASWGPEDDGKTVDGPARLA 270
+L G ++D V+ + + + S G +T+D A
Sbjct 240 VLRSNGSGTMSDVVKGVEWAAEAHIKKSKKGDKKFKGSVANMSLGG-GSSRTLDLAVNAA 298
Query 271 EEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYS 330
+A G F A+GN D+CN + +++ ++T ++S
Sbjct 299 VDA------------GIHFAVAAGND--NADACNYSPAA-AEKAITVGASTLADERAYFS 343
Query 331 E--ACSSTLATTYSSGNQNEKQIVTTDLRQK-CTESHTGTSASAPLAAGIIALTLEANK- 386
C+ A I++T + T + +GTS ++P AG++A +
Sbjct 344 NYGKCTDIFA--------PGLNILSTWVGSDHATNTISGTSMASPHIAGLLAYYVSLAPA 395
Query 387 --------NLTWRDMQHLVVQTSKPAHLNA 408
++T + ++ ++ + L
Sbjct 396 KDSAYAVADVTPKQLKAALISVATEGTLTD 425
>sp|P9WEW5|PCH18_PENRB Subtilisin-like serine protease Pen ch
18 OS=Penicillium rubens OX=1108849 PE=1 SV=1
Length=494
Score = 170 bits (431), Expect = 2e-44, Method: Composition-based stats.
Identities = 72/390 (18%), Positives = 136/390 (35%), Gaps = 80/390 (21%)
Query 52 HGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDV 109
GF + F H +H + + H +++R P V ++E+ R
Sbjct 83 FGFDF--EAFMGLKHTFHIAGSLLGYAGHFHEDVIEQIRRHPDVDYIEKDSEVRTMSEGS 140
Query 110 YQEPTDPKFPQQWYLSGVTQRDL----NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG 165
++ W L+ ++ R+ N G G+ ++D G H D G
Sbjct 141 VEK------NAPWGLARISHRESLSFGNFNKYLYAEEGGEGVDAYVIDTGANVKHVDFEG 194
Query 166 NYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVR 225
+ G + D D D N HGT C+G +A GVA A + V+
Sbjct 195 RANWGKTIPQGDADED---------GNGHGTHCSGTIAGKK------FGVAKKANVYAVK 239
Query 226 ML----DGEVTDAVEARSLGLNPN-----------HIHIYSASWGPEDDGKTVDGPARLA 270
+L G ++D V+ + + + S G +T+D A
Sbjct 240 VLRSNGSGTMSDVVKGVEWAAEAHIKKSKKGDKKFKGSVANMSLGG-GSSRTLDLAVNAA 298
Query 271 EEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYS 330
+A G F A+GN D+CN + +++ ++T ++S
Sbjct 299 VDA------------GIHFAVAAGND--NADACNYSPAA-AEKAITVGASTLADERAYFS 343
Query 331 E--ACSSTLATTYSSGNQNEKQIVTTDLRQK-CTESHTGTSASAPLAAGIIALTLEANK- 386
C+ A I++T + T + +GTS ++P AG++A +
Sbjct 344 NYGKCTDIFA--------PGLNILSTWVGSDHATNTISGTSMASPHIAGLLAYYVSLAPA 395
Query 387 --------NLTWRDMQHLVVQTSKPAHLNA 408
++T + ++ ++ + L
Sbjct 396 KDSAYAVADVTPKQLKAALISVATEGTLTD 425
>sp|P9WEW6|PCH18_PENCH Subtilisin-like serine protease EN45_078720
OS=Penicillium chrysogenum OX=5076 GN=EN45_078720 PE=3
SV=1
Length=494
Score = 170 bits (431), Expect = 2e-44, Method: Composition-based stats.
Identities = 72/390 (18%), Positives = 136/390 (35%), Gaps = 80/390 (21%)
Query 52 HGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDV 109
GF + F H +H + + H +++R P V ++E+ R
Sbjct 83 FGFDF--EAFMGLKHTFHIAGSLLGYAGHFHEDVIEQIRRHPDVDYIEKDSEVRTMSEGS 140
Query 110 YQEPTDPKFPQQWYLSGVTQRDL----NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG 165
++ W L+ ++ R+ N G G+ ++D G H D G
Sbjct 141 VEK------NAPWGLARISHRESLSFGNFNKYLYAEEGGEGVDAYVIDTGANVKHVDFEG 194
Query 166 NYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVR 225
+ G + D D D N HGT C+G +A GVA A + V+
Sbjct 195 RANWGKTIPQGDADED---------GNGHGTHCSGTIAGKK------FGVAKKANVYAVK 239
Query 226 ML----DGEVTDAVEARSLGLNPN-----------HIHIYSASWGPEDDGKTVDGPARLA 270
+L G ++D V+ + + + S G +T+D A
Sbjct 240 VLRSNGSGTMSDVVKGVEWAAEAHIKKSKKGDKKFKGSVANMSLGG-GSSRTLDLAVNAA 298
Query 271 EEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYS 330
+A G F A+GN D+CN + +++ ++T ++S
Sbjct 299 VDA------------GIHFAVAAGND--NADACNYSPAA-AEKAITVGASTLADERAYFS 343
Query 331 E--ACSSTLATTYSSGNQNEKQIVTTDLRQK-CTESHTGTSASAPLAAGIIALTLEANK- 386
C+ A I++T + T + +GTS ++P AG++A +
Sbjct 344 NYGKCTDIFA--------PGLNILSTWVGSDHATNTISGTSMASPHIAGLLAYYVSLAPA 395
Query 387 --------NLTWRDMQHLVVQTSKPAHLNA 408
++T + ++ ++ + L
Sbjct 396 KDSAYAVADVTPKQLKAALISVATEGTLTD 425
>sp|P29140|ISP_SHOCL Intracellular alkaline protease OS=Shouchella
clausii OX=79880 PE=3 SV=1
Length=321
Score = 165 bits (417), Expect = 4e-44, Method: Composition-based stats.
Identities = 62/294 (21%), Positives = 106/294 (36%), Gaps = 39/294 (13%)
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND 191
+ A W G G ++ ++D G + +HPDLA G VN ++
Sbjct 28 VEAPAVWKASAKGAGQIIGVIDTGCQVDHPDLAERIIGG----VNLTTDYGGVETNFSDN 83
Query 192 NRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNP------- 244
N HGT AG VAA A G VGVA A + ++ L G+ + + + +
Sbjct 84 NGHGTHVAGTVAA-AETGSGVVGVAPKADLFIIKALSGDGSGEMGWIAKAIRYAVDWRGP 142
Query 245 --NHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDS 302
+ I + S G D + + +A VS V A+GN G +
Sbjct 143 KGEQMRIITMSLGGPTDSEELH-------DAVKYAVSNN-----VSVVCAAGNEGDGRED 190
Query 303 CNCDGYTNSIY-TLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCT 361
N Y + +++ + + + G + +
Sbjct 191 TNEFAYPAAYNEVIAVGAVDFDLRLSDFPNTNEEIDIVAPGVG-------IKSTYLDSGY 243
Query 362 ESHTGTSASAPLAAGIIALTLEANKN-----LTWRDMQHLVVQTSKPAHLNAND 410
+GTS +AP AG +AL + K+ L+ ++ +V+ + P A D
Sbjct 244 AELSGTSMAAPHVAGALALIINLAKDAFKRTLSETEICAQLVRRATPIGFTAQD 297
>sp|C5FII2|SUB8_ARTOC Subtilisin-like protease 8 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB8
PE=3 SV=1
Length=490
Score = 169 bits (429), Expect = 4e-44, Method: Composition-based stats.
Identities = 74/404 (18%), Positives = 138/404 (34%), Gaps = 66/404 (16%)
Query 33 TWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQRE 90
TW I + + +++ F + F H + S H +++R
Sbjct 62 TWVQEIHT-STESKRLKKRNQFTFKNEAFDGLKHTFDIAGGLLGYSGHFDEEVIEQVRRH 120
Query 91 PQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL----NVKAAWAQGYTGHG 146
P V+++E+ ++ R V + W L+ ++ R G G
Sbjct 121 PDVEYIERD-SEVRALESVTEN------GAPWGLARISHRKRLNFGTFNKYIYAAQGGEG 173
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D G H D G G + ND D D N HGT C+G +A
Sbjct 174 VDAYVIDTGTNIEHVDFEGRASWGKTIPENDDDID---------GNGHGTHCSGTIAGKK 224
Query 207 NNGVCGVGVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWG------P 256
GVA A + V++L G ++D V+ + + G
Sbjct 225 ------YGVAKKAHVHAVKVLRTSGSGTMSDVVKGVQWAAESHLKQVGETKKGNRKGFKG 278
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
++ G + + V +G F A+GN D+CN S +++
Sbjct 279 SVANMSLGGGKSVTLDR----VVDQAVAVGMHFAVAAGND--NADACNYSPAA-SQNSIT 331
Query 317 ISSATQFGNVPWYSE--ACSSTLATTYSSGNQNEKQIVTTDLRQKCT-ESHTGTSASAPL 373
+ ++T ++S C+ A I +T + K + +GTS ++P
Sbjct 332 VGASTLTDERAYFSNYGKCTDIFA--------PGLNIQSTWIGSKYAVNTISGTSMASPH 383
Query 374 AAGIIALTLEANK---------NLTWRDMQHLVVQTSKPAHLNA 408
G++A L +T +M+ ++ + L
Sbjct 384 ICGLLAYFLSLQPASDSAFAVAEITPAEMKENMISIASKNALTD 427
>sp|C5P4Z8|SUB8_COCP7 Subtilisin-like protease CPC735_031240 OS=Coccidioides
posadasii (strain C735) OX=222929 GN=CPC735_031240
PE=3 SV=1
Length=497
Score = 169 bits (429), Expect = 5e-44, Method: Composition-based stats.
Identities = 72/364 (20%), Positives = 125/364 (34%), Gaps = 56/364 (15%)
Query 44 VANSVARKHG-FLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQV 100
+A RK F F H + + S H +++R P VQ++E+
Sbjct 72 MAKRSLRKRNQFPFKNDAFDGLKHTYDIAGSIMGYSGHFDEEVIEQVRRHPDVQYIEKDS 131
Query 101 AKRRTKRDVYQEPTDPKFPQQWYLSGVTQRD---LNVKAAW-AQGYTGHGIVVSILDDGI 156
V + W L+ V+ RD + + G G+ V ++D G
Sbjct 132 EVHAWDEPVTEN------NAPWGLARVSHRDSLTMGTFNKYLYAANGGEGVDVYVIDTGT 185
Query 157 EKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVA 216
H D G G + D D D N HGT C+G VA GVA
Sbjct 186 NIEHVDFEGRAHWGKTIPTGDDDVD---------GNGHGTHCSGTVAGKK------YGVA 230
Query 217 YNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIY------SASWGPEDDGKTVDGP 266
A + V++L G ++D V+ + + + ++ ++ G
Sbjct 231 KKANVYAVKVLRSNGSGTMSDVVKGVEWAAGAHLSKMVEARKKGNKAFKGSAANMSLGGG 290
Query 267 ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNV 326
+ G F A+GN D+CN + +++ ++T
Sbjct 291 KSFTLDLAVNAAV----DAGIHFAVAAGND--NADACNYSPAA-AEKAVTVGASTLADER 343
Query 327 PWYSE--ACSSTLATTYSSGNQNEKQIVTTDLRQKCT-ESHTGTSASAPLAAGIIALTLE 383
++S C+ A I++T + K + +GTS ++P AG++A L
Sbjct 344 AYFSNYGKCTDIFA--------PGLNILSTWIGSKYAVNTISGTSMASPHVAGLLAYFLS 395
Query 384 ANKN 387
Sbjct 396 LQPE 399
>sp|P33295|PEPC_ASPNG Subtilisin-like serine protease pepC OS=Aspergillus
niger OX=5061 GN=pepC PE=3 SV=1
Length=533
Score = 167 bits (423), Expect = 5e-43, Method: Composition-based stats.
Identities = 88/517 (17%), Positives = 178/517 (34%), Gaps = 78/517 (15%)
Query 32 NTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQR 89
++W I + + ++ F +++ + + + S H +++R
Sbjct 61 HSWVQDIHDSQSERTELKKRSLFGLGDEVYLGLKNTFDIAGSLIGYSGHFHEDVIEQVRR 120
Query 90 EPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL----NVKAAWAQGYTGH 145
P V ++E+ +V+ + W L+ ++ RD N G
Sbjct 121 HPDVDYIERD-------SEVHTMEGATEKNAPWGLARISHRDSLTFGNFNKYLYASEGGE 173
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G+ +D GI +H D G G + ND+D ++ N HGT C+G +A
Sbjct 174 GVDAYTIDTGINVDHVDFEGRATWGKTIPTNDED---------LDGNGHGTHCSGTMAGK 224
Query 206 ANNGVCGVGVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWG------ 255
GVA A + V++L G ++D V + + A G
Sbjct 225 K------YGVAKKANLYAVKVLRSSGSGTMSDVVSGVEYAVQAHIKKAKDAKNGKVKGFK 278
Query 256 PEDDGKTVDGP-ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYT 314
++ G ++ E+A GV G F A+GN D+CN +
Sbjct 279 GSVANMSLGGGKSKTLEDAVNAGVEAGLH-----FAVAAGND--NADACNYSPAA-AEKA 330
Query 315 LSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC-TESHTGTSASAPL 373
+++ ++T ++S ++ G I++T + T +GTS ++P
Sbjct 331 ITVGASTLADERAYFSNYG--ECTDIFAPG----LNILSTWIGSNYATNIISGTSMASPH 384
Query 374 AAGIIALTLEANK---------NLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSY 424
AG++A + LT ++ ++ + L + +
Sbjct 385 IAGLLAYFVSLQPSSDSAFAVEELTPAKLKKDIIAIATEGALTDIP--------SNTPNV 436
Query 425 GYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRL 484
+ + L Q ++++ T + R + +T + + + TR
Sbjct 437 SHAAVGIYKRNELTQKFSSLPGTVVVPRTTPTSLAAVATRSPLPRTASRTVLRVS-FTRP 495
Query 485 EHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPH 521
+ R + R + P RS L+ +R
Sbjct 496 KSCSPRSLVPSTARSRM------PSSHRSELVLSRRR 526
>sp|P54423|WPRA_BACSU Cell wall-associated protease OS=Bacillus
subtilis (strain 168) OX=224308 GN=wprA PE=1 SV=2
Length=894
Score = 171 bits (434), Expect = 6e-43, Method: Composition-based stats.
Identities = 78/418 (19%), Positives = 141/418 (34%), Gaps = 70/418 (17%)
Query 59 QIFGDYYHF------WHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQE 112
++F + Y F G S + + L + V++ E ++
Sbjct 361 KLFDNLYSFELPKDEKQNGAYTASAKRVKSAAATLSKMSNVEFAEP-------VQEYKSL 413
Query 113 PTDPKFPQQWYL------SGVTQRDLNVKAAWAQGYTGHG----IVVSILDDGIEKNHPD 162
D ++P QW L GV D+ + A +++++D G++ D
Sbjct 414 ANDIQYPYQWPLKNNGENGGVKNADVKYEPA--NTLLSKRKLNDTLIAVVDTGVDSTLAD 471
Query 163 LAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIG 222
L G + ++ M+D HGT AG +AA ++NG G+ A+I
Sbjct 472 LKGKVRTDLGHNFVGRNN------NAMDDQGHGTHVAGIIAAQSDNGYSMTGLNAKAKII 525
Query 223 GVRMLDGEVTDAVEARSLGL---NPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVS 279
V++LD + E +LG+ + + S G G +R+ E A
Sbjct 526 PVKVLDSAGSGDTEQIALGIKYAADKGAKVINLSLG--------GGYSRVLEFALKYAA- 576
Query 280 QGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLAT 339
+ ASGN G S +S Y +S+ + + +S +
Sbjct 577 ----DKNVLIAAASGNDGENALSYPA----SSKYVMSVGATNRMDMTADFSNYGKGLDIS 628
Query 340 TYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQ 399
S + + + +GTS + P AA L N L +++ ++ +
Sbjct 629 APGSD-------IPSLVPNGNVTYMSGTSMATPYAAAAAGLLFAQNPKLKRTEVEDMLKK 681
Query 400 TSKPAHLNANDWATNGV------------GRKVSHSYGYGLLDAGAMVALAQNWTTVA 445
T+ + D + V GYG L+ V+ A V
Sbjct 682 TADDISFESVDGGEEELYDDYGDPIEIPKTPGVDWHSGYGRLNVMKAVSAADLQLKVN 739
>sp|B7ZK61|CH901_DAVTA Subtilisin-like serine protease Cla h 9.0101
OS=Davidiella tassiana OX=29918 PE=1 SV=1
Length=518
Score = 165 bits (418), Expect = 2e-42, Method: Composition-based stats.
Identities = 77/417 (18%), Positives = 143/417 (34%), Gaps = 85/417 (20%)
Query 57 LGQIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPT 114
+ IF H ++ + H +++R P V+ +E+ + E
Sbjct 87 VDDIFNGLKHTYNIAGGLMGYAGHFDEDVIEQIRRHPDVELVERDQEVHVLGSESEVEKN 146
Query 115 DPKFPQQWYLSGVTQRDLNVKAAWAQGY----TGHGIVVSILDDGIEKNHPDLAGNYDPG 170
P W L+ ++ RD + + G G+ V ++D G +H D G G
Sbjct 147 AP-----WGLARISHRDSLSFGTFNKYLYTEDGGEGVDVYVVDTGTNVDHVDFEGRASWG 201
Query 171 ASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML--- 227
+ D D D N HGT C+G VA GVA A + V++L
Sbjct 202 KTIPQGDADED---------GNGHGTHCSGTVAGKK------YGVAKKAHVKAVKVLRSN 246
Query 228 -DGEVTDAVEARSLGLNPNHIHI---------------YSASWGPEDDGKTVDGPARLAE 271
G ++D V+ + + + S G G + + +
Sbjct 247 GSGSMSDVVKGVEYAAESHLEQVSITKKGKRKGFKGSTANMSLG--------GGKSPILD 298
Query 272 EAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSE 331
+A V G F A+GN DSCN + +++ ++T ++S
Sbjct 299 KAVNAAV-----DAGIHFAVAAGND--NADSCNYSPAA-AENAVTVGASTLADERAYFSN 350
Query 332 --ACSSTLATTYSSGNQNEKQIVTTDLRQKCT-ESHTGTSASAPLAAGIIALTLEANK-- 386
C+ A I +T + K + +GTS ++P AG++A L
Sbjct 351 YGKCNDIFA--------PGLNIQSTWIGSKYAVNTISGTSMASPHVAGLLAYLLSLQPAK 402
Query 387 -------NLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
+++ + ++ ++ + L + + G G + A+V
Sbjct 403 DSAFAVADISPKKLKANLISIATVGALTDVP-SNTANILAWN---GGGESNYSAIVE 455
>sp|B3V0K8|CL401_COCLU Subtilisin-like serine protease Cur l 4.0101
OS=Cochliobolus lunatus OX=5503 PE=1 SV=1
Length=506
Score = 164 bits (416), Expect = 3e-42, Method: Composition-based stats.
Identities = 75/372 (20%), Positives = 128/372 (34%), Gaps = 48/372 (13%)
Query 32 NTW--AVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHS--RL 87
+ W +V R ++F H + K S H + +
Sbjct 59 HDWVQSVHSKNTQERMELRKRSSDLPVSNEVFAGLKHTYELSGLK-GYSGHFDDETLEAI 117
Query 88 QREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGY----T 143
+ P V ++E+ R D + + W L+ ++ RD W +
Sbjct 118 RNHPDVDYIERDSEVRILGGDEPETENN----SPWGLARISHRDSLSFGTWNKYLYAADG 173
Query 144 GHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVA 203
G G+ V ++D G +H D G G + D D D N HGT C+G VA
Sbjct 174 GEGVDVYVIDTGTNVDHVDFEGRAKWGKTIPNGDADED---------GNGHGTHCSGTVA 224
Query 204 AVANNGVCGVGVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSA--SWGPE 257
GVA A + V++L G ++D V+ + + +A
Sbjct 225 GKK------YGVAKKAHVYAVKVLRSNGSGTMSDVVKGVEFAAKSHSEAVSAAKNGKKKG 278
Query 258 DDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSI 317
G T + + G F A+GN DSCN + +++
Sbjct 279 FKGSTANMSLGGGKSTTLDMAVNAAVDAGLHFAVAAGND--NADSCNYSPAA-AENAVTV 335
Query 318 SSATQFGNVPWYSE--ACSSTLATTYSSGNQNEKQIVTTDLRQK-CTESHTGTSASAPLA 374
++T ++S C+ A I++T + K T + +GTS ++P
Sbjct 336 GASTLLDERAYFSNYGKCNDIFA--------PGLNILSTWIGSKHATNTISGTSMASPHI 387
Query 375 AGIIALTLEANK 386
AG++A L
Sbjct 388 AGLLAYMLSLQP 399
>sp|C5PCB1|SUB4A_COCP7 Subtilisin-like protease CPC735_066880
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_066880
PE=3 SV=1
Length=397
Score = 160 bits (405), Expect = 1e-41, Method: Composition-based stats.
Identities = 69/376 (18%), Positives = 133/376 (35%), Gaps = 51/376 (14%)
Query 53 GFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVY 110
G + + R + + + +V+++E R
Sbjct 63 GHVRRNGTLTGLKTTFDIS-GFRGYLGAFDHDTLDEILADDKVKFVEPNRIMRI------ 115
Query 111 QEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPG 170
+ T + W L+ ++ G G+++ +D GI+ NHPD G G
Sbjct 116 -QGTQTQRGAPWGLARLSSSRPGGSDYVYDDRAGEGVIIYGVDTGIDVNHPDFEGRATWG 174
Query 171 ASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE 230
+ D + N HGT AG A GVA A I GV++LD +
Sbjct 175 INTIDQDN----------TDGNGHGTHTAGTFAGAR------FGVAKKATIVGVKVLDAQ 218
Query 231 VTDAVEAR--SLGLNPNHIHIYSASWGPEDDGKTVDGP-ARLAEEAFFRGVSQGRGGLGS 287
+ + A + + +H + + G ++ G ++ +A R V G
Sbjct 219 GSGSNSAIMEGISWSVDHAR-KNNALGRAVMNLSLGGSFSQAVNDAAERAVR-----AGV 272
Query 288 IFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQN 347
A+GN ++ + + N ++ + + +S S + ++ G
Sbjct 273 FLAVAAGNDNQDASNYSPASAPN---VCTVGATDRMDVRATFSNFGS--VLDIFAPGVDV 327
Query 348 EKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTS-----K 402
E + + T+ +GTS +AP AG+ A + NL + + Q +
Sbjct 328 E-----STMPGGGTQMMSGTSMAAPHIAGLGAYLMSTE-NLQPSQVCDRIKQLASNSVRN 381
Query 403 PAHLNANDWATNGVGR 418
P + + + A NG+G+
Sbjct 382 PGNGSTSKLANNGIGQ 397
>sp|P25036|YSP3_YEAST Subtilisin-like protease 3 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=YSP3
PE=2 SV=2
Length=478
Score = 162 bits (410), Expect = 1e-41, Method: Composition-based stats.
Identities = 71/339 (21%), Positives = 128/339 (38%), Gaps = 48/339 (14%)
Query 61 FGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKF 118
FG +F+ R + + + ++P ++++EQ+ + + + +E
Sbjct 122 FGGIDNFFDINGLFRGYTGYFTDEIIKIISQDPIIKFVEQETTVKISNSSLQEEAP---- 177
Query 119 PQQWYLSGVTQRDLNVKA----AWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFD 174
W L V+ R+ + G G+ +LD GI+ H D G + GA
Sbjct 178 ---WGLHRVSHREKPKYGQDLEYLYEDAAGKGVTSYVLDTGIDTEHEDFEGRAEWGAVIP 234
Query 175 VNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDA 234
ND+ D N HGT CAG + G GVA N +I V++L
Sbjct 235 ANDEASDL---------NGHGTHCAGII------GSKHFGVAKNTKIVAVKVLRSNGEGT 279
Query 235 VEARSLGLNP-NHIHI-----YSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
V G+ HI + + ++ LA E G
Sbjct 280 VSDVIKGIEYVTKEHIESSKKKNKEFKGSTANLSLGSSKSLAMEMAVNAAVDS----GVH 335
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNE 348
F A+GN + D+C + ++++ ++T + ++S T ++ G
Sbjct 336 FAIAAGNE--DEDACLSSP-AGAEKSITVGASTFSDDRAFFSNWG--TCVDVFAPG---- 386
Query 349 KQIVTTDLRQKC-TESHTGTSASAPLAAGIIALTLEANK 386
I++T + + T S +GTS ++P AGI++ L
Sbjct 387 INIMSTYIGSRNATLSLSGTSMASPHVAGILSYFLSLQP 425
>sp|Q9Y755|PENC2_PENCI Subtilisin-like serine protease Pen c 2
OS=Penicillium citrinum OX=5077 PE=1 SV=1
Length=457
Score = 161 bits (408), Expect = 1e-41, Method: Composition-based stats.
Identities = 71/386 (18%), Positives = 131/386 (34%), Gaps = 68/386 (18%)
Query 52 HGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDV 109
GF F H +H + + H +++R P V ++E+
Sbjct 83 FGFDT--DAFLGVKHSFHVAGSLMGYAGHFHEDVIEQVRRHPDVDYIEKDSEVH------ 134
Query 110 YQEPTDPKFPQQWYLSGVTQRD------LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDL 163
+ + + W L+ ++ RD N G G G+ ++D G +H D
Sbjct 135 HFDSPSVEKNAPWGLARISHRDSLSFGTFNKYLYAEDG--GEGVDAYVIDTGTNTDHVDF 192
Query 164 AGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGG 223
G G + D+D D N HGT C+G +A GVA A +
Sbjct 193 EGRASWGKTIPQGDEDVD---------GNGHGTHCSGTIAGKK------YGVAKKANVYA 237
Query 224 VRML----DGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLA-----EEAF 274
V++L G ++D V+ HI + + K G
Sbjct 238 VKVLRSNGSGTMSDVVKGVEWAAE---AHIKKSKAAKDGKAKGFKGSVANMSLGGGSSRT 294
Query 275 FRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSE--A 332
G F A+GN D+CN + +++ ++T ++S
Sbjct 295 LDLAVNAAVDAGMHFAVAAGND--NADACNYSPAA-AEKAVTVGASTLADERAYFSNYGK 351
Query 333 CSSTLATTYSSGNQNEKQIVTTDLRQKCT-ESHTGTSASAPLAAGIIALTLEANKN---- 387
C+ A I++T + K + +GTS ++P AG++A + +
Sbjct 352 CTDIFA--------PGLNILSTWIGSKYAVNTISGTSMASPHIAGLLAYYVSLQPSDDSA 403
Query 388 -----LTWRDMQHLVVQTSKPAHLNA 408
+T + ++ ++ + L
Sbjct 404 FAVEKITPKKLKEALITVATSGALTD 429
>sp|P06873|PRTK_PARAQ Proteinase K OS=Parengyodontium album OX=37998
GN=PROK PE=1 SV=2
Length=384
Score = 160 bits (404), Expect = 1e-41, Method: Composition-based stats.
Identities = 55/310 (18%), Positives = 110/310 (35%), Gaps = 39/310 (13%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
L+ P V+++EQ + W L+ ++ + G G
Sbjct 87 LRAHPDVEYIEQDAVVTI---------NAAQTNAPWGLARISSTSPGTSTYYYDESAGQG 137
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
V ++D GIE +HP+ G ++ + +D N HGT CAG V
Sbjct 138 SCVYVIDTGIEASHPEFEGRAQMVKTYYYSSRD-----------GNGHGTHCAGTV---- 182
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
G GVA ++ GV++LD + G++ + P+ ++
Sbjct 183 --GSRTYGVAKKTQLFGVKVLDDNGSGQYSTIIAGMDF-VASDKNNRNCPKGVVASLSLG 239
Query 267 ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNV 326
+ + G + A+GN + + + + ++ ++ ++
Sbjct 240 GGY--SSSVNSAAARLQSSGVMVAVAAGNNNADARNYSP---ASEPSVCTVGASDRYDRR 294
Query 327 PWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANK 386
+S S + + G I++T + T S +GTS + P AG+ A + K
Sbjct 295 SSFSNYGS--VLDIFGPG----TSILSTWI-GGSTRSISGTSMATPHVAGLAAYLMTLGK 347
Query 387 NLTWRDMQHL 396
+++
Sbjct 348 TTAASACRYI 357
>sp|Q3ZEJ8|SUB6_TRITO Subtilisin-like protease 6 OS=Trichophyton
tonsurans OX=34387 GN=SUB6 PE=3 SV=1
Length=412
Score = 160 bits (405), Expect = 2e-41, Method: Composition-based stats.
Identities = 62/343 (18%), Positives = 116/343 (34%), Gaps = 44/343 (13%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ V ++E R + D W L+ V+ + + G G
Sbjct 103 ISSHDDVDYIEPDFVVRTSTNGTNLTRQDNVPS--WGLARVSSKKAGGTTYYYDSSAGKG 160
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D GI+ NH D G G +F + + N HGT AG V
Sbjct 161 VTAYVIDTGIDINHEDFRGRAKWGKNFVDD----------MDEDCNGHGTHVAGTVGGTK 210
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
G+A + V++LD E + + G+ + AS G K
Sbjct 211 ------YGLAKGVSLVAVKVLDCEGSGSNSGVIKGMEW---AMREASGGGNGTAKAAGKA 261
Query 267 ARL-----AEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
++ G A+GN + + + +++++T
Sbjct 262 VMNMSLGGTRSQASNQAAKAISDAGIFMAVAAGNENMDAQHSSP---ASEPSVCTVAAST 318
Query 322 QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALT 381
+ +S L Y+ G + +T+ T++ +GTS ++P G+ A
Sbjct 319 EDDGKADFSNYG--QLVDVYAPG-----KDITSLKPGGSTDTLSGTSMASPHVCGLGAYL 371
Query 382 L----EANKNL--TWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ + L T ++M H +Q +P + NG G+
Sbjct 372 IGLGKQGGPGLCDTIKEMAHDAIQ--RPGEGTTSKLIYNGSGK 412
>sp|A1XIH0|SUB6_TRIEQ Subtilisin-like protease 6 OS=Trichophyton
equinum OX=63418 GN=SUB6 PE=1 SV=1
Length=412
Score = 160 bits (404), Expect = 2e-41, Method: Composition-based stats.
Identities = 62/343 (18%), Positives = 116/343 (34%), Gaps = 44/343 (13%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ V ++E R + D W L+ V+ + + G G
Sbjct 103 ISSHDDVDYIEPDFVVRTSTNGTNLTRQDNVPS--WGLARVSSKKAGGTTYYYDSSAGKG 160
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D GI+ NH D G G +F + + N HGT AG V
Sbjct 161 VTAYVIDTGIDINHEDFRGRAKWGKNFVDD----------MDEDCNGHGTHVAGTVGGTK 210
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
G+A + V++LD E + + G+ + AS G K
Sbjct 211 ------YGLAKGVSLVAVKVLDCEGSGSNSGVIKGMEW---AMREASGGGNGTAKAAGKA 261
Query 267 ARLA-----EEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
++ G A+GN + + + +++++T
Sbjct 262 VMNMSLGGPRSQASNQAAKAISDAGIFMAVAAGNENMDAQHSSP---ASEPSVCTVAAST 318
Query 322 QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALT 381
+ +S L Y+ G + +T+ T++ +GTS ++P G+ A
Sbjct 319 EDDGKADFSNYG--QLVDVYAPG-----KDITSLKPGGSTDTLSGTSMASPHVCGLGAYL 371
Query 382 L----EANKNL--TWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ + L T ++M H +Q +P + NG G+
Sbjct 372 IGLGKQGGPGLCDTIKEMAHDAIQ--RPGEGTTSKLIYNGSGK 412
>sp|P87184|ALP2_ASPFU Alkaline protease 2 OS=Aspergillus fumigatus
(strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)
OX=330879 GN=alp2 PE=1 SV=1
Length=495
Score = 161 bits (408), Expect = 3e-41, Method: Composition-based stats.
Identities = 74/405 (18%), Positives = 144/405 (36%), Gaps = 64/405 (16%)
Query 32 NTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQR 89
++W I + ++ F + + + + + S H ++++
Sbjct 61 HSWVQDIHSAQNERVELRKRSLFGFGEEAYLGLKNTFDIAGSLVGYSGHFHEDVIEQVRK 120
Query 90 EPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKA----AWAQGYTGH 145
P V+++E+ ++ T D E + P W L+ ++ RD G
Sbjct 121 HPDVEYIEKD-SEVHTMEDPTVEKSAP-----WGLARISHRDSLSFGTFNKYLYASEGGE 174
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G+ +D GI +H D G G + +D+D D N HGT C+G +A
Sbjct 175 GVDAYTIDTGINVDHVDFEGRAQWGKTIPTDDEDAD---------GNGHGTHCSGTIAGR 225
Query 206 ANNGVCGVGVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWG------ 255
GVA A + V++L G ++D V + + + A G
Sbjct 226 K------YGVAKKANLYAVKVLRSSGSGTMSDVVAGVEWAVKSHLKKVKDAKDGKIKGFK 279
Query 256 PEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTL 315
++ G EA + G F A+GN D+CN + +
Sbjct 280 GSVANMSLGGGKSRTLEAAVNAGVE----AGLHFAVAAGND--NADACNYSPAA-AENPI 332
Query 316 SISSATQFGNVPWYSE--ACSSTLATTYSSGNQNEKQIVTTDLRQK-CTESHTGTSASAP 372
++ ++T ++S C+ A I++T + K + +GTS ++P
Sbjct 333 TVGASTLQDERAYFSNYGKCTDIFA--------PGLNILSTWIGSKHAVNTISGTSMASP 384
Query 373 LAAGIIALTLEANK---------NLTWRDMQHLVVQTSKPAHLNA 408
AG++A + LT + ++ ++ + L
Sbjct 385 HIAGLLAYFVSLQPSKDSAFAVDELTPKKLKKDIIAIATQGALTD 429
>sp|B0Y473|ALP2_ASPFC Alkaline protease 2 OS=Aspergillus fumigatus
(strain CBS 144.89 / FGSC A1163 / CEA10) OX=451804 GN=alp2
PE=3 SV=1
Length=495
Score = 161 bits (408), Expect = 3e-41, Method: Composition-based stats.
Identities = 74/405 (18%), Positives = 144/405 (36%), Gaps = 64/405 (16%)
Query 32 NTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQR 89
++W I + ++ F + + + + + S H ++++
Sbjct 61 HSWVQDIHSAQNERVELRKRSLFGFGEEAYLGLKNTFDIAGSLVGYSGHFHEDVIEQVRK 120
Query 90 EPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKA----AWAQGYTGH 145
P V+++E+ ++ T D E + P W L+ ++ RD G
Sbjct 121 HPDVEYIEKD-SEVHTMEDPTVEKSAP-----WGLARISHRDSLSFGTFNKYLYASEGGE 174
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G+ +D GI +H D G G + +D+D D N HGT C+G +A
Sbjct 175 GVDAYTIDTGINVDHVDFEGRAQWGKTIPTDDEDAD---------GNGHGTHCSGTIAGR 225
Query 206 ANNGVCGVGVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWG------ 255
GVA A + V++L G ++D V + + + A G
Sbjct 226 K------YGVAKKANLYAVKVLRSSGSGTMSDVVAGVEWAVKSHLKKVKDAKDGKIKGFK 279
Query 256 PEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTL 315
++ G EA + G F A+GN D+CN + +
Sbjct 280 GSVANMSLGGGKSRTLEAAVNAGVE----AGLHFAVAAGND--NADACNYSPAA-AENPI 332
Query 316 SISSATQFGNVPWYSE--ACSSTLATTYSSGNQNEKQIVTTDLRQK-CTESHTGTSASAP 372
++ ++T ++S C+ A I++T + K + +GTS ++P
Sbjct 333 TVGASTLQDERAYFSNYGKCTDIFA--------PGLNILSTWIGSKHAVNTISGTSMASP 384
Query 373 LAAGIIALTLEANK---------NLTWRDMQHLVVQTSKPAHLNA 408
AG++A + LT + ++ ++ + L
Sbjct 385 HIAGLLAYFVSLQPSKDSAFAVDELTPKKLKKDIIAIATQGALTD 429
>sp|E4V2V9|SUB7_ARTGP Subtilisin-like protease 7 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB7
PE=3 SV=1
Length=400
Score = 159 bits (401), Expect = 3e-41, Method: Composition-based stats.
Identities = 57/332 (17%), Positives = 120/332 (36%), Gaps = 40/332 (12%)
Query 59 QIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ H + + S H + + + V+++E+ + + + P
Sbjct 71 KAMTGMKHTYRFPTGMKGYSGHFDEQMINEIAKRADVKYIERDARVQINA--IEMQDNVP 128
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
W L+ V ++ + G G+ ++D G + H + +G G +F +
Sbjct 129 S----WGLARVGSKEPGGTTYYYDSSAGQGVTAYVIDTGTDIKHEEFSGRATWGGNFVDD 184
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVE 236
M+ N HGT +G VA GVA A + GV++LD + + +
Sbjct 185 ----------IDMDCNGHGTHVSGTVAGTK------FGVAKKANVVGVKVLDCDGSGSNS 228
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
+G+ G ++ G A ++QG G A+GN
Sbjct 229 GVIMGMEFATNDAKKKGAGKAVANMSLGGAFSQASNDAAAAIAQG----GVFLAVAAGND 284
Query 297 GREHDSCNCDGYTNSIYTL-SISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTD 355
+ S ++ +++++T+ +S + Y+ G+ +T+
Sbjct 285 NVDA----AMASPASEPSICTVAASTEQDGKASFSNYG--QVVDVYAPGDG-----ITSA 333
Query 356 LRQKCTESHTGTSASAPLAAGIIALTLEANKN 387
++ +GTS ++P AG+ A + K+
Sbjct 334 KPGGGSQVLSGTSMASPHVAGLAAYLIGTGKS 365
>sp|P09232|PRTB_YEAST Cerevisin OS=Saccharomyces cerevisiae (strain
ATCC 204508 / S288c) OX=559292 GN=PRB1 PE=1 SV=1
Length=635
Score = 163 bits (413), Expect = 5e-41, Method: Composition-based stats.
Identities = 62/311 (20%), Positives = 121/311 (39%), Gaps = 46/311 (15%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRD-LNV---KAAWAQGY 142
+++ P V ++E+ T+ D + W L+ ++ R+ LN+
Sbjct 262 IRQNPLVDFVERDSIVEATEF-------DTQNSAPWGLARISHRERLNLGSFNKYLYDDD 314
Query 143 TGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEV 202
G G+ ++D G+ NH D G + +ND+D ++ N HGT CAG +
Sbjct 315 AGRGVTSYVIDTGVNINHKDFEKRAIWGKTIPLNDED---------LDGNGHGTHCAGTI 365
Query 203 AAVANNGVCGVGVAYNARIGGVRML----DGEVTDAVEARSLG--LNPNHIHIYSASWGP 256
A GVA NA + V++L G ++D V+ + +
Sbjct 366 A------SKHYGVAKNANVVAVKVLRSNGSGTMSDVVKGVEYAAKAHQKEAQEKKKGFKG 419
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
++ G A + + +G F A+GN D+CN ++ ++
Sbjct 420 STANMSLGGGKSPALDLAVNAAVE----VGIHFAVAAGNE--NQDACNTSP-ASADKAIT 472
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLR-QKCTESHTGTSASAPLAA 375
+ ++T + ++S ++ G I++T + T + +GTS ++P A
Sbjct 473 VGASTLSDDRAYFSNWGK--CVDVFAPG----LNILSTYIGSDDATATLSGTSMASPHVA 526
Query 376 GIIALTLEANK 386
G++ L
Sbjct 527 GLLTYFLSLQP 537
>sp|P23653|PRTR_PARAQ Proteinase R OS=Parengyodontium album OX=37998
GN=PROR PE=1 SV=1
Length=387
Score = 157 bits (397), Expect = 1e-40, Method: Composition-based stats.
Identities = 59/329 (18%), Positives = 111/329 (34%), Gaps = 44/329 (13%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
L+ P V+++EQ W L+ ++ G G
Sbjct 90 LRAHPDVEYIEQDAIVNINAEQRNAP---------WGLARISSTSPGTSTYRYDDSAGQG 140
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
V ++D G+E +HP+ G ++ + +D N HGT CAG +
Sbjct 141 TCVYVIDTGVEASHPEFEGRAQMVKTYYASSRD-----------GNGHGTHCAGTI---- 185
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN--PNHIHIYSASWGPEDDGKTVD 264
G GVA +I GV++L+ + + G++ N + G
Sbjct 186 --GSRTYGVAKKTQIFGVKVLNDQGSGQYSTIISGMDFVANDYRNRNCPNGVVASMSIGG 243
Query 265 GPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFG 324
G + A G + A+GN + + + + ++ + ++
Sbjct 244 GYSSSVNSAAAN-----LQQSGVMVAVAAGNNNADARNYSP---ASESSICTVGATDRYD 295
Query 325 NVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA 384
+S S + I++T + T S +GTS + P AG+ A +
Sbjct 296 RRSSFSNYGSVLDIFAPGT------DILSTWI-GGSTRSISGTSMATPHVAGLAAYLMTL 348
Query 385 NKNLTWRDMQHLVVQTSKPAHLNANDWAT 413
T + + QT+ L+ + T
Sbjct 349 G-RATASNACRYIAQTANQGDLSNISFGT 376
>sp|E4V4J8|SUB6_ARTGP Subtilisin-like protease 6 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB6
PE=3 SV=1
Length=408
Score = 156 bits (394), Expect = 4e-40, Method: Composition-based stats.
Identities = 57/336 (17%), Positives = 116/336 (35%), Gaps = 42/336 (13%)
Query 59 QIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ H + G T ++ + + V ++E+ + T + Q+ P
Sbjct 73 KPMAGMQHKFSLGGTFKAYTGEFDEAMIKDISNHDDVDFIERDTVVKATA--ITQQDNVP 130
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
W L+ V ++ + G G+ I+D GI+ +H D G G +F
Sbjct 131 S----WGLARVGSKEAGGSTYYYDDTAGKGVTAYIIDTGIDIHHGDFGGRAKWGKNFV-- 184
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVE 236
+ N HG+ AG V GVA + V++LD E + +
Sbjct 185 --------DKMDEDCNGHGSHVAGTVGGTK------FGVAKGVNLVAVKVLDCEGSGSNS 230
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLA-----EEAFFRGVSQGRGGLGSIFVW 291
+G+ + AS G K ++ G
Sbjct 231 GVIMGMEW---AMKEASGGGNSTAKAAGKSVMNMSLGGPRSEASNKAAKAIADAGIFMAV 287
Query 292 ASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQI 351
A+GN + + + +++++++ + +S + + Y+ GN+
Sbjct 288 AAGNDNMDAQHSSP---ASEPSICTVAASSEDDSKADFSNYGA--VVDIYAPGNE----- 337
Query 352 VTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKN 387
+T+ T++ +GTS ++P G+ A + K
Sbjct 338 ITSVKPGNGTDTLSGTSMASPHVCGLGAYLIGLGKE 373
>sp|Q8J077|SUB6_TRISH Subtilisin-like protease 6 (Fragment) OS=Trichophyton
schoenleinii OX=34386 GN=SUB6 PE=1 SV=1
Length=405
Score = 156 bits (393), Expect = 5e-40, Method: Composition-based stats.
Identities = 51/308 (17%), Positives = 104/308 (34%), Gaps = 40/308 (13%)
Query 87 LQREPQVQWLEQQVAKRRTKR--DVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
+ V ++E R + ++ ++ P W L+ V + + G
Sbjct 101 ISNHDDVDYIEPDFVVRTSTNGTNLTRQENVPS----WGLARVGSKQAGGTTYYYDSSAG 156
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G+ ++D GI+ H D G G +F + N HGT AG V
Sbjct 157 KGVTAYVIDTGIDIEHEDFGGRAKWGKNFV----------DQRDEDCNGHGTHVAGTVGG 206
Query 205 VANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVD 264
G+A + + V++LD + + + G+ + AS G K
Sbjct 207 TK------YGLAKSVSLVAVKVLDCDGSGSNSGVIRGMEW---AMREASGGGNGTAKAAG 257
Query 265 GPARLA-----EEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISS 319
++ G A+GN + + + ++++
Sbjct 258 KSVMNMSLGGPRSQASNDAARAISEAGIFMAVAAGNENMDAQHSSP---ASEPSVCTVAA 314
Query 320 ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIA 379
+T+ +S + + Y+ G + +T+ T++ +GTS ++P G+ A
Sbjct 315 STEDDGKAEFSNYGA--VVDVYAPG-----KDITSLKPGGSTDTLSGTSMASPHVCGLGA 367
Query 380 LTLEANKN 387
+ K
Sbjct 368 YLIGLGKQ 375
>sp|P40903|ISP6_SCHPO Sexual differentiation process putative
subtilase-type proteinase isp6 OS=Schizosaccharomyces pombe
(strain 972 / ATCC 24843) OX=284812 GN=isp6 PE=2 SV=1
Length=467
Score = 156 bits (395), Expect = 9e-40, Method: Composition-based stats.
Identities = 61/319 (19%), Positives = 121/319 (38%), Gaps = 41/319 (13%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLN---VKAAWAQGY 142
+++ P V +E+ K + + W L+ ++ + + +
Sbjct 158 QIRLHPHVIAVERDQVVSIKKLE-------TQSGAPWGLARISHKSVKYDDIGKYVYDSS 210
Query 143 TGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEV 202
G I ++D G+ +H + G GA+ D D D +N HGT AG +
Sbjct 211 AGDNITAYVVDTGVSIHHVEFEGRASWGATIPSGDVDED---------NNGHGTHVAGTI 261
Query 203 AAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKT 262
A+ A GVA A I V++L + + G+ H S+ +
Sbjct 262 ASRA------YGVAKKAEIVAVKVLRSSGSGTMADVIAGVEWTVRHHKSSGKKTSVGNMS 315
Query 263 VDGPARLAEE-AFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
+ G + A V+ G I+ A+GN D+C S +++ ++T
Sbjct 316 LGGGNSFVLDMAVDSAVTN-----GVIYAVAAGNE--YDDACYSSPAA-SKKAITVGAST 367
Query 322 QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQK-CTESHTGTSASAPLAAGIIAL 380
+ ++S S ++ G I++T + T + +GTS + P AG+ A
Sbjct 368 INDQMAYFSNYGS--CVDIFAPG----LNILSTWIGSNTSTNTISGTSMATPHVAGLSAY 421
Query 381 TLEANKNLTWRDMQHLVVQ 399
L + + +++ +++
Sbjct 422 YLGLHPAASASEVKDAIIK 440
>sp|E4UN97|SUB3_ARTGP Subtilisin-like protease 3 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB3
PE=3 SV=1
Length=397
Score = 154 bits (390), Expect = 1e-39, Method: Composition-based stats.
Identities = 66/350 (19%), Positives = 119/350 (34%), Gaps = 42/350 (12%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R + H + + + +V+++E + + +P P W L V+ +
Sbjct 84 RGYNGHFDEATIESILNDDKVKYVEHDRVVKLAA--LVTQPNAP----TWGLGRVSHKAK 137
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
K G G+ + +D GI+ NHP+ G G + ND + N
Sbjct 138 GNKDFVYDSSAGQGVTIYGVDTGIDINHPEFRGRIRWGTNTVDNDN----------TDGN 187
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS- 251
HGT AG A GVA A I V++L + + G++ S
Sbjct 188 GHGTHTAGTFAGTT------YGVAKKANIVAVKVLSAGGSGSTAGVIKGIDWCVTDARSK 241
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
+ G ++ G A G A+GN R+ + + ++
Sbjct 242 GALGKAALNLSLGGSFSQAN----NDAVTRAQEAGIFVAVAAGNDNRDAKNSSP---ASA 294
Query 312 IYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASA 371
+ +S+T +S T+ Y+ G+ + + T + +GTS ++
Sbjct 295 PAVCTAASSTIDDVKSSFSNWG--TIIDIYAPGSS-----ILSAAPGGGTRTLSGTSMAS 347
Query 372 PLAAGIIALTLEANKNLTW---RDMQHLVVQTSKPAHLNANDWATNGVGR 418
P G+ A + ++ R Q P N NG G+
Sbjct 348 PHVCGVGAAMIAQGVSVAQVCNRMKQIANAVIRNPGTGTTNRLLYNGSGQ 397
>sp|L8GD75|SUB3_PSED2 Subtilisin-like protease 3 OS=Pseudogymnoascus
destructans (strain ATCC MYA-4855 / 20631-21) OX=658429
GN=SP3 PE=1 SV=1
Length=404
Score = 154 bits (389), Expect = 2e-39, Method: Composition-based stats.
Identities = 68/357 (19%), Positives = 123/357 (34%), Gaps = 56/357 (16%)
Query 52 HGFLNLGQ-IFGDYYHFWHRGVTK-RSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDV 109
H FL+ F H + K + +R+ + P V ++++ V V
Sbjct 59 HSFLSKRDSTFRGLGHKYKMPKFKGYQIESDMDTVNRISQSPHVAYVDKDVKVSAYDLSV 118
Query 110 YQEPTDPKFPQQWYLSGVTQRD---LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN 166
+ W L ++ R+ ++ G G + I+D G+ H + G
Sbjct 119 -------RIGAPWGLDRISHRNGTSPGLEEYTYDSSAGGGTTIYIIDTGVYIEHVEFEGR 171
Query 167 YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM 226
GA+F P +++ HGT AG +AA AN GVA A+I VR+
Sbjct 172 ATFGANF---------IPGSPDTDEDGHGTHVAG-IAAGAN-----FGVASKAKIIAVRV 216
Query 227 LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGG-- 284
LD G+ W +D GK + + S+
Sbjct 217 LDANGDGKGSNVLAGMQ----------WAADDAGKKNQTAKSVINMSLGADYSEAFNKAT 266
Query 285 -----LGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLAT 339
G + V A+GN + +++ +++ + + + +S +
Sbjct 267 EAIIAKGIVVVAAAGNEDANASGVSP---ASTVDAITVGATDRNDSRAAFSNWGVALDVF 323
Query 340 TYSSGNQNEKQIVTTDLRQKCTE-SHTGTSASAPLAAGIIA--LTLEANKNLTWRDM 393
I++ + K + +GTS + P AG+ A + LE N T +
Sbjct 324 APG------VDILSAWIGGKDANKTISGTSMACPHVAGLAAYFIGLEKNGTSTPSKI 374
>sp|Q8J0D7|SUB3_ARTOT Subtilisin-like protease 3 OS=Arthroderma
otae OX=63405 GN=SUB3 PE=1 SV=1
Length=397
Score = 154 bits (388), Expect = 2e-39, Method: Composition-based stats.
Identities = 67/350 (19%), Positives = 123/350 (35%), Gaps = 42/350 (12%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R+ + H + + + +V ++E + + +P P W L V+ +
Sbjct 84 RAYNGHFDEATIESILNDDKVDYVEHDRVVKLAA--LTTQPNAP----TWGLGRVSHKAP 137
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
K G G+ + +D GI+ NHP+ G G + ND + N
Sbjct 138 GNKDFVYDSSAGQGVTIYGVDTGIDINHPEFRGRIRWGTNTVDNDN----------TDGN 187
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS- 251
HGT AG A GVA A I V++L + + G++ +
Sbjct 188 GHGTHTAGTFAGTT------YGVAKKANIVAVKVLSAGGSGSTAGVIKGIDWCVTDAKAK 241
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
+ G ++ G +A V++ G A+GN ++ + + ++
Sbjct 242 GALGKAALNLSLGG---AFSQANNDAVTR-AQNAGIFVAVAAGNDNKDAKNSSP---ASA 294
Query 312 IYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASA 371
+ +S+T +S T+ Y+ G+ + + T + +GTS ++
Sbjct 295 PAVCTAASSTIDDQKSSFSNWG--TIVDIYAPGSN-----ILSAAPGGGTRTLSGTSMAS 347
Query 372 PLAAGIIALTLEANKNLTW---RDMQHLVVQTSKPAHLNANDWATNGVGR 418
P G+ A L ++ R Q P N NG GR
Sbjct 348 PHVCGVGAAMLAQGVSVAQACDRIKQIANAVIKNPGTGTTNKLLYNGSGR 397
>sp|C5FMY5|SUB3_ARTOC Subtilisin-like protease 3 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB3
PE=3 SV=1
Length=397
Score = 154 bits (388), Expect = 2e-39, Method: Composition-based stats.
Identities = 67/350 (19%), Positives = 123/350 (35%), Gaps = 42/350 (12%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R+ + H + + + +V ++E + + +P P W L V+ +
Sbjct 84 RAYNGHFDEATIESILNDDKVDYVEHDRVVKLAA--LTTQPNAP----TWGLGRVSHKAP 137
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
K G G+ + +D GI+ NHP+ G G + ND + N
Sbjct 138 GNKDFVYDSSAGQGVTIYGVDTGIDINHPEFRGRIRWGTNTVDNDN----------TDGN 187
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS- 251
HGT AG A GVA A I V++L + + G++ +
Sbjct 188 GHGTHTAGTFAGTT------YGVAKKANIVAVKVLSAGGSGSTAGVIKGIDWCVTDAKAK 241
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
+ G ++ G +A V++ G A+GN ++ + + ++
Sbjct 242 GALGKAALNLSLGG---AFSQANNDAVTR-AQNAGIFVAVAAGNDNKDAKNSSP---ASA 294
Query 312 IYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASA 371
+ +S+T +S T+ Y+ G+ + + T + +GTS ++
Sbjct 295 PAVCTAASSTIDDQKSSFSNWG--TIVDIYAPGSN-----ILSAAPGGGTRTLSGTSMAS 347
Query 372 PLAAGIIALTLEANKNLTW---RDMQHLVVQTSKPAHLNANDWATNGVGR 418
P G+ A L ++ R Q P N NG GR
Sbjct 348 PHVCGVGAAMLAQGVSVAQACDRIKQIANAVIKNPGTGTTNKLLYNGSGR 397
>sp|P16397|SUBF_BACSU Bacillopeptidase F OS=Bacillus subtilis
(strain 168) OX=224308 GN=bpr PE=1 SV=2
Length=1433
Score = 161 bits (408), Expect = 2e-39, Method: Composition-based stats.
Identities = 82/412 (20%), Positives = 142/412 (34%), Gaps = 63/412 (15%)
Query 83 RHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTD-PKFPQQWYLSGVTQRDLNVKA----- 136
S+ E VQ+ E + KR +++ + Q + + NV
Sbjct 151 HASKEVMEKVVQFPEVEKVLPNEKRQLFKSSSPFNMKKAQKAIKATDGVEWNVDQIDAPK 210
Query 137 AWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS------------FDVNDQDPDPQP 184
AWA GY G G VV+ +D G+E NHP L Y +D + P
Sbjct 211 AWALGYDGTGTVVASIDTGVEWNHPALKEKYRGYNPENPNEPENEMNWYDAVAGEASPY- 269
Query 185 RYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVT---DAVEARSLG 241
+D HGT G + +G +GVA A+ V+ + D +EA
Sbjct 270 -----DDLAHGTHVTGTMVGSEPDGTNQIGVAPGAKWIAVKAFSEDGGTDADILEAGEWV 324
Query 242 LNPNHI----------HIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVW 291
L P + + SWG + ++R + +
Sbjct 325 LAPKDAEGNPHPEMAPDVVNNSWGGGSG-----------LDEWYRDMVNAWRAADIFPEF 373
Query 292 ASGNG-----GREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQ 346
++GN G N Y S T + + +S S +
Sbjct 374 SAGNTDLFIPGGPGSIANPANYPESFAT---GATDINKKLADFSLQGPSPYDEIKPEISA 430
Query 347 NEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
I ++ Q + GTS + P + + AL +AN +L+ +M+ ++ T++P
Sbjct 431 PGVNIRSSVPGQTYEDGWDGTSMAGPHVSAVAALLKQANASLSVDEMEDILTSTAEPLTD 490
Query 407 NANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEP 458
+ + N + YG+GL++A V+ + A + + EP
Sbjct 491 STFPDSPN-------NGYGHGLVNAFDAVSAVTDGLGKAEGQVSVEGDDQEP 535
>sp|A1XIH1|SUB6_TRISD Subtilisin-like protease 6 OS=Trichophyton
soudanense OX=69891 GN=SUB6 PE=1 SV=1
Length=412
Score = 153 bits (387), Expect = 3e-39, Method: Composition-based stats.
Identities = 61/343 (18%), Positives = 114/343 (33%), Gaps = 44/343 (13%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ V ++E R T D W L+ V + + G G
Sbjct 103 ISSHDDVDFIEPDFVVRTTTNGTNLTHQDNVPS--WGLARVGSKKPGGTTYYYDPSAGKG 160
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ I+D GI+ +H D G G +F + N HGT AG V
Sbjct 161 VTAYIIDTGIDIDHEDFQGRAKWGENFVDQQN----------TDCNGHGTHVAGTVGGTK 210
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
G+A + V++LD + + + G+ + AS G K
Sbjct 211 ------YGLAKGVSLVAVKVLDCDGSGSNSGVIKGMEW---AMRQASGGGNGTAKAAGKS 261
Query 267 ARLA-----EEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
++ G A+GN + + + +++++T
Sbjct 262 VMNMSLGGPRSEASNQAAKAISDAGIFMAVAAGNENMDAQHSSP---ASEPSVCTVAAST 318
Query 322 QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALT 381
+ +S + + Y+ G + +T+ T++ +GTS ++P G+ A
Sbjct 319 KDDGKADFSNYGA--VVDVYAPG-----KDITSLKPGGSTDTLSGTSMASPHVCGLGAYL 371
Query 382 L----EANKNL--TWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ + L T + M + V+Q+ P NG G+
Sbjct 372 IGLGKQGGPGLCDTIKKMANDVIQS--PGEGTTGKLIYNGSGK 412
>sp|Q9UW97|SUB6_TRIRU Subtilisin-like protease 6 OS=Trichophyton
rubrum OX=5551 GN=SUB6 PE=1 SV=1
Length=412
Score = 153 bits (387), Expect = 3e-39, Method: Composition-based stats.
Identities = 61/343 (18%), Positives = 114/343 (33%), Gaps = 44/343 (13%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ V ++E R T D W L+ V + + G G
Sbjct 103 ISSHDDVDFIEPDFVVRTTTNGTNLTHQDNVPS--WGLARVGSKKPGGTTYYYDPSAGKG 160
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ I+D GI+ +H D G G +F + N HGT AG V
Sbjct 161 VTAYIIDTGIDIDHEDFQGRAKWGENFVDQQN----------TDCNGHGTHVAGTVGGTK 210
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
G+A + V++LD + + + G+ + AS G K
Sbjct 211 ------YGLAKGVSLVAVKVLDCDGSGSNSGVIKGMEW---AMRQASGGGNGTAKAAGKS 261
Query 267 ARLA-----EEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
++ G A+GN + + + +++++T
Sbjct 262 VMNMSLGGPRSEASNQAAKAISDAGIFMAVAAGNENMDAQHSSP---ASEPSVCTVAAST 318
Query 322 QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALT 381
+ +S + + Y+ G + +T+ T++ +GTS ++P G+ A
Sbjct 319 KDDGKADFSNYGA--VVDVYAPG-----KDITSLKPGGSTDTLSGTSMASPHVCGLGAYL 371
Query 382 L----EANKNL--TWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ + L T + M + V+Q+ P NG G+
Sbjct 372 IGLGKQGGPGLCDTIKKMANDVIQS--PGEGTTGKLIYNGSGK 412
>sp|Q32ZM1|RM201_RHOMI Subtilisin-like serine protease Rho m 2.0101
(Fragment) OS=Rhodotorula mucilaginosa OX=5537 PE=1 SV=1
Length=342
Score = 151 bits (382), Expect = 4e-39, Method: Composition-based stats.
Identities = 68/367 (19%), Positives = 134/367 (37%), Gaps = 61/367 (17%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL----NVKAAWAQG 141
++++ P V ++E+ + V + W L+ ++ RD +
Sbjct 11 QVRQLPMVNFIEKNSLVHANEFTVAKGAP-------WGLARISHRDPLSLGSFDQYLYDS 63
Query 142 YTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGE 201
G G+ ++D G+ +H G G + D+D D N HGT CAG
Sbjct 64 NGGTGVTSYVIDTGVNVHHEQFEGRAKWGKTIPQGDEDED---------GNGHGTHCAGT 114
Query 202 VAAVANNGVCGVGVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWGPE 257
+ G GVA NA I V++L G ++D ++ + + +
Sbjct 115 I------GSNAYGVAKNAEIVAVKVLRSNGSGSMSDVIKGVEFAVKSHQDSVKKGKNSFS 168
Query 258 DDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSI 317
++ G A + + G F A+GN D+CN ++ +++
Sbjct 169 TANMSLGGGKSPALDLAVNAAVK----AGLHFAVAAGNE--NQDACNTSP-ASAENAITV 221
Query 318 SSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLR-QKCTESHTGTSASAPLAAG 376
++T ++S ++ G I++T + T +GTS ++P AG
Sbjct 222 GASTISDARAYFSNYGK--CVDIFAPG----LNILSTYIGSDAATAYLSGTSMASPHIAG 275
Query 377 IIALTLEANKN-----------LTWRDMQHLVVQTSKPAHLNA------NDWATNGVGRK 419
++ L + +T ++ ++ P L N A NG G+
Sbjct 276 LLTYYLSLQPSSDSEFFIGAEGITPAQLKKNLIAFGTPDVLADIPADTPNILAFNGAGQN 335
Query 420 VSHSYGY 426
++ +G+
Sbjct 336 LTKFWGH 342
>sp|B8XGQ6|SUB3_TRITO Subtilisin-like protease 3 OS=Trichophyton
tonsurans OX=34387 GN=SUB3 PE=3 SV=1
Length=397
Score = 153 bits (385), Expect = 5e-39, Method: Composition-based stats.
Identities = 68/350 (19%), Positives = 120/350 (34%), Gaps = 42/350 (12%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R+ + H + + + +V ++E + + +P P W L V+ R
Sbjct 84 RAYNGHFDEATIESILNDDKVNYVEHDRVVKLAA--LVTQPNAP----TWGLGRVSHRAP 137
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
+ G GI + +D GI+ HP+ AG G + ND + N
Sbjct 138 GNRDFVYDSSAGQGITIYGVDTGIDIRHPEFAGRIRWGTNTVDNDN----------TDGN 187
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS- 251
HGT AG A GVA A I V++L + + G++ + S
Sbjct 188 GHGTHTAGTFAGTT------YGVAKKANIVAVKVLSAGGSGSTAGVIKGIDWCVTDVRSR 241
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
+ G ++ G A G A+GN R+ + + ++
Sbjct 242 NALGKAALNLSLGGSFSQAN----NDAVTRAQEAGIFVAVAAGNDNRDARNYSP---ASA 294
Query 312 IYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASA 371
+ +S+T +S S + Y+ G+ + + T + +GTS ++
Sbjct 295 PAVCTAASSTIDDQKSSFSNWGS--IVDIYAPGSS-----ILSAAPGGGTRTLSGTSMAS 347
Query 372 PLAAGIIALTLEANKNLTW---RDMQHLVVQTSKPAHLNANDWATNGVGR 418
P G+ A L ++ R Q P N NG G+
Sbjct 348 PHVCGVGAAMLAQGVSVAQVCNRLKQIGNAVIRNPGTSTTNRLLYNGSGQ 397
>sp|C5FH27|SUB9_ARTOC Subtilisin-like protease 9 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB9
PE=3 SV=1
Length=395
Score = 152 bits (383), Expect = 9e-39, Method: Composition-based stats.
Identities = 62/336 (18%), Positives = 116/336 (35%), Gaps = 44/336 (13%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
R+ R V ++E + + + P W L ++ + G
Sbjct 99 RITRSSDVDYVEADRVVKMAA--LNTQRNAPS----WGLGRISHKKAGSFDYVYDSDAGS 152
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
GI + +D GI+ +HPD G G + ++ + N HGT AG A
Sbjct 153 GITIYGVDTGIDIHHPDFGGRATWGVNTVDSEN----------SDQNGHGTHTAGTFAGA 202
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDG 265
GVA ARI V++L+ E T + G+ + H AS ++
Sbjct 203 T------YGVAKKARIIAVKVLNAEGTGSTSGVIQGIEWSTNH---ASSNGLSGKAAMNL 253
Query 266 PARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGN 325
+ + F ++ G A+GN G ++ ++++
Sbjct 254 SLGVRSSSVFNSAAEAAQRSGIFLAVAAGNDGFSP--------ASARGVCTVAATDAQDQ 305
Query 326 VPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE-- 383
+S S+ Y+ G++ + + T + +GTS ++P G+ A +
Sbjct 306 ATSWSNYGST--VALYAPGDK-----ILSIYPNGGTATLSGTSMASPHVCGVGAYLMALE 358
Query 384 -ANKNLTWRDMQHLVVQTSK-PAHLNANDWATNGVG 417
++ L +++ K P NG G
Sbjct 359 GIGPGRVCDRIKQLALESVKNPGPDTTRRLLYNGSG 394
>sp|P08594|AQL1_THEAQ Aqualysin-1 OS=Thermus aquaticus OX=271
GN=pstI PE=1 SV=2
Length=513
Score = 154 bits (390), Expect = 9e-39, Method: Composition-based stats.
Identities = 68/328 (21%), Positives = 119/328 (36%), Gaps = 51/328 (16%)
Query 88 QREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGI 147
++ P V+++E R + P W L + QRDL + ++ TG G+
Sbjct 110 RQSPDVEFIEADKVVRAWA---------TQSPAPWGLDRIDQRDLPLSNSYTYTATGRGV 160
Query 148 VVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVAN 207
V ++D GI H + G G +D + + N HGT AG + V
Sbjct 161 NVYVIDTGIRTTHREFGGRARVG--YDALGGNG--------QDCNGHGTHVAGTIGGVT- 209
Query 208 NGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PNHIH--IYSASWGPEDDGKT 262
GVA + VR+LD + + G++ NH + + S G
Sbjct 210 -----YGVAKAVNLYAVRVLDCNGSGSTSGVIAGVDWVTRNHRRPAVANMSLG------- 257
Query 263 VDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQ 322
G + + A ++ G A+GN + + + L++ + T
Sbjct 258 -GGVSTALDNAVKNSIAAGVVYA-----VAAGNDNANACNYSPARVAEA---LTVGATTS 308
Query 323 FGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTL 382
+S S ++ G T+D T++ GTS + P AG+ AL L
Sbjct 309 SDARASFSNYGS--CVDLFAPGASIPSAWYTSDT---ATQTLNGTSMATPHVAGVAALYL 363
Query 383 EANKNLTWRDMQHLVVQTSKPAHLNAND 410
E N + T + ++ + L+
Sbjct 364 EQNPSATPASVASAILNGATTGRLSGIG 391
>sp|Q9UTS0|PSP3_SCHPO Subtilase-type proteinase psp3 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=psp3
PE=2 SV=1
Length=451
Score = 153 bits (386), Expect = 9e-39, Method: Composition-based stats.
Identities = 60/348 (17%), Positives = 119/348 (34%), Gaps = 65/348 (19%)
Query 65 YHFWHRGVTKRSLSPHRPR--HSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQW 122
H + G + + LQ+ P + +E + W
Sbjct 120 KHTFEIGDAFLGYAGRFSPWLVAELQKHPDIALVEPDRVMHVMTEQTFAP---------W 170
Query 123 YLSGVTQRD----LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ 178
L+ V+ R + G G+ ++D GI H D G GA+
Sbjct 171 GLARVSHRKKLGFFTMTRYQYNETAGEGVTAYVIDTGINIEHQDFQGRATWGATIP---- 226
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEAR 238
+++D+ HGT AG +A GV+ NA++ V+++ + T V
Sbjct 227 -----TGEGEVDDHGHGTHVAGTIAGKT------FGVSKNAKLVAVKVMRADGTGTVSDI 275
Query 239 SLGLN----------PNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
G+ + + + S G + A A + G G
Sbjct 276 IKGIEFAFKQSKKDKESIASVVNMSIGGD---------ASTALDLAVNAAIAG----GLF 322
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNE 348
F A+GN + + +N+ +++ ++T + +S S ++ G+
Sbjct 323 FAVAAGNDAEDACGTSPARVSNA---MTVGASTWNDQIASFSNIGS--CVDIFAPGS--- 374
Query 349 KQIVTTDLRQKCTES--HTGTSASAPLAAGIIALTLEANKNLTWRDMQ 394
++ +D S +GTS ++P AG+ A + + +L ++
Sbjct 375 --LILSDWIGSNRASMILSGTSMASPHVAGLAAYFISLDPSLANHPVE 420
>sp|C5FJA5|SUB7_ARTOC Subtilisin-like protease 7 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB7
PE=3 SV=1
Length=400
Score = 151 bits (382), Expect = 1e-38, Method: Composition-based stats.
Identities = 54/326 (17%), Positives = 114/326 (35%), Gaps = 38/326 (12%)
Query 59 QIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ G H + + S H +++ + V+++E+ + + ++ P
Sbjct 71 KAMGGMKHTYKFPTGMKGYSGHFDEDMINQIAKHSDVKYIERDARVQINA--ITEQDNVP 128
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
W L+ V R+ + G G I+D G + H + G G++F +
Sbjct 129 S----WGLARVGSREAGGSTYYYDSTAGEGSTAYIIDTGTDIEHEEFEGRATWGSNFVDD 184
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVE 236
M+ N HGT +G V GVA + I V++LD + +
Sbjct 185 ----------MDMDCNGHGTHVSGTVGGAT------FGVAKKSNIVAVKVLDCNGSGSNS 228
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
+G+ ++ G A ++ G G A+GN
Sbjct 229 GVIMGMEWATNDAKKKGADKAVANMSLGGAFSQASNDAAAAIANG----GVFLAVAAGND 284
Query 297 GREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL 356
+ + + + +++++T+ +S + Y+ G+ +T+
Sbjct 285 NVDAANSSP---ASEPSICTVAASTEQDGKADFSNFG--QVVDVYAPGDS-----ITSAK 334
Query 357 RQKCTESHTGTSASAPLAAGIIALTL 382
++ +GTS + P AG+ A +
Sbjct 335 PGGGSQVLSGTSMATPHVAGLAAYFI 360
>sp|Q64K31|SUB6_ARTBE Subtilisin-like protease 6 OS=Arthroderma
benhamiae OX=63400 GN=SUB6 PE=3 SV=1
Length=412
Score = 152 bits (383), Expect = 1e-38, Method: Composition-based stats.
Identities = 67/365 (18%), Positives = 123/365 (34%), Gaps = 48/365 (13%)
Query 68 WHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLS 125
+ G R+ S + V ++E R T D W L+
Sbjct 82 YSLGNVFRAYSGEFDEAMIKDISGHDDVDFIEPDFVVRTTTNGTNLTHQDNVPS--WGLA 139
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPR 185
V + + G G+ I+D GI+ +H D G G +F +
Sbjct 140 RVGSKQAGGTTYYYDPSAGKGVRAYIIDTGIDTDHKDFGGRAKWGKNFADD--------- 190
Query 186 YTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPN 245
+ N HGT AG V G+A + + V++LD E + + G+
Sbjct 191 -MDQDCNGHGTHVAGTVGGTQ------YGLAKSVSLIAVKVLDCEGSGSNSGVIKGMEW- 242
Query 246 HIHIYSASWGPEDDGKTVDGPARLA------EEAFFRGVSQGRGGLGSIFVWASGNGGRE 299
+ AS G K EA + G A+GN +
Sbjct 243 --AMRDASGGGNGTAKAAGKTVMNMSLGGPRSEATNQAAKAISD-AGIFLAVAAGNENMD 299
Query 300 HDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQK 359
+ + +++++T+ +S S+ Y+ G + +T+
Sbjct 300 AQHSSP---ASEPSVCTVAASTKDDGKASFSNYGSA--VDVYAPG-----KDITSLKPGG 349
Query 360 CTESHTGTSASAPLAAGIIALTL----EANKNL--TWRDMQHLVVQTSKPAHLNANDWAT 413
T++ +GTS ++P G+ A + + L T ++M + +Q+ P +
Sbjct 350 STDTLSGTSMASPHVCGLGAYLIGLGKQGGPGLCDTIKEMANDAIQS--PGEDTTSKLIY 407
Query 414 NGVGR 418
NG G+
Sbjct 408 NGSGK 412
>sp|D4ALV9|SUB6_ARTBC Subtilisin-like protease 6 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB6
PE=2 SV=1
Length=412
Score = 152 bits (383), Expect = 1e-38, Method: Composition-based stats.
Identities = 67/365 (18%), Positives = 123/365 (34%), Gaps = 48/365 (13%)
Query 68 WHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLS 125
+ G R+ S + V ++E R T D W L+
Sbjct 82 YSLGNVFRAYSGEFDEAMIKDISGHDDVDFIEPDFVVRTTTNGTNLTHQDNVPS--WGLA 139
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPR 185
V + + G G+ I+D GI+ +H D G G +F +
Sbjct 140 RVGSKQAGGTTYYYDPSAGKGVRAYIIDTGIDTDHKDFGGRAKWGKNFADD--------- 190
Query 186 YTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPN 245
+ N HGT AG V G+A + + V++LD E + + G+
Sbjct 191 -MDQDCNGHGTHVAGTVGGTQ------YGLAKSVSLIAVKVLDCEGSGSNSGVIKGMEW- 242
Query 246 HIHIYSASWGPEDDGKTVDGPARLA------EEAFFRGVSQGRGGLGSIFVWASGNGGRE 299
+ AS G K EA + G A+GN +
Sbjct 243 --AMRDASGGGNGTAKAAGKTVMNMSLGGPRSEATNQAAKAISD-AGIFLAVAAGNENMD 299
Query 300 HDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQK 359
+ + +++++T+ +S S+ Y+ G + +T+
Sbjct 300 AQHSSP---ASEPSVCTVAASTKDDGKASFSNYGSA--VDVYAPG-----KDITSLKPGG 349
Query 360 CTESHTGTSASAPLAAGIIALTL----EANKNL--TWRDMQHLVVQTSKPAHLNANDWAT 413
T++ +GTS ++P G+ A + + L T ++M + +Q+ P +
Sbjct 350 STDTLSGTSMASPHVCGLGAYLIGLGKQGGPGLCDTIKEMANDAIQS--PGEDTTSKLIY 407
Query 414 NGVGR 418
NG G+
Sbjct 408 NGSGK 412
>sp|D4D5H3|SUB6_TRIVH Subtilisin-like protease 6 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB6 PE=3 SV=1
Length=412
Score = 151 bits (381), Expect = 2e-38, Method: Composition-based stats.
Identities = 63/342 (18%), Positives = 108/342 (32%), Gaps = 42/342 (12%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ V ++E R T D W L+ V+ R + G G
Sbjct 103 ISSHDDVDFIEPDFVVRATTNGTNLTHQDNVPS--WGLARVSTRKPGGTTYYYDPSAGKG 160
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D GI+ H D G G + + N HGT AG V
Sbjct 161 VTAYVIDTGIDTKHEDFGGRAKWGKNLV----------DQMDEDCNGHGTHVAGTVGGTK 210
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
G+A + V++LD E + + G+ + AS G K
Sbjct 211 ------YGLAKGVSLVAVKVLDCEGSGSNSGVIKGMEW---AMMDASGGGNGTAKAAGKA 261
Query 267 ARLA------EEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA 320
EA + G A+GN + + + +++++
Sbjct 262 VMNMSLGGPRSEATNQAAKAISD-AGIFLAVAAGNENMDAQHSSP---ASEPSVCTVAAS 317
Query 321 TQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIAL 380
T+ +S S + Y+ G K IV+ T++ +GTS ++P G+ A
Sbjct 318 TKDDGKANFSNFGS--VVDVYAPG----KDIVSL-KPGGGTDTLSGTSMASPHVCGLGAY 370
Query 381 TL----EANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ + L Q P + NG G+
Sbjct 371 LIGLGKQGGPGLCDTIKQMATDAIQSPGEDTTSKLIYNGSGK 412
>sp|Q5VJ72|SUB6_TRIVC Subtilisin-like protease 6 OS=Trichophyton
verrucosum OX=63417 GN=SUB6 PE=3 SV=1
Length=412
Score = 151 bits (381), Expect = 2e-38, Method: Composition-based stats.
Identities = 65/344 (19%), Positives = 115/344 (33%), Gaps = 46/344 (13%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ V ++E R T D W L+ V+ R + G G
Sbjct 103 ISSHDDVDFIEPDFVVRATTNGTNLTHQDNVPS--WGLARVSTRKPGGTTYYYDPSAGKG 160
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D GI+ H D G G + + N HGT AG V
Sbjct 161 VTAYVIDTGIDTKHEDFGGRAKWGKNLV----------DQMDEDCNGHGTHVAGTVGGTK 210
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
G+A + V++LD E + + G+ + AS G K
Sbjct 211 ------YGLAKGVSLVAVKVLDCEGSGSNSGVIKGMEW---AMMDASGGGNGTAKAAGKA 261
Query 267 ARLA------EEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA 320
EA + G A+GN + + + +++++
Sbjct 262 VMNMSLGGPRSEATNQAAKAISD-AGIFLAVAAGNENMDAQHSSP---ASEPSVCTVAAS 317
Query 321 TQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIAL 380
T+ +S S + Y+ G K IV+ T++ +GTS ++P G+ A
Sbjct 318 TKDDGKANFSNFGS--VVDVYAPG----KDIVSL-KPGGGTDTLSGTSMASPHVCGLGAY 370
Query 381 TL----EANKNL--TWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ + L T ++M + +Q+ P + NG G+
Sbjct 371 LIGLGKQGGPGLCDTIKEMANDAIQS--PGEDTTSKLIYNGSGK 412
>sp|B6VA86|SUB3_TRIEQ Subtilisin-like protease 3 OS=Trichophyton
equinum OX=63418 GN=SUB3 PE=3 SV=1
Length=397
Score = 150 bits (379), Expect = 3e-38, Method: Composition-based stats.
Identities = 68/350 (19%), Positives = 119/350 (34%), Gaps = 42/350 (12%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R+ + H + + + +V ++E + + +P P W L V+ R
Sbjct 84 RAYNGHFDEATIESILNDDKVNYVEHDRVVKLAA--LVTQPNAP----TWGLGRVSHRAP 137
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
+ G GI + +D GI+ HP+ AG G + ND + N
Sbjct 138 GNRDFVYDSSAGQGITIYGVDTGIDIRHPEFAGRIRWGTNTVDNDN----------TDGN 187
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS- 251
HGT AG A GVA A I V++L + + G++ S
Sbjct 188 GHGTHTAGTFAGTT------YGVAKKANIVAVKVLSAGGSGSTAGVIKGIDWCVTDARSR 241
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
+ G ++ G A G A+GN R+ + + ++
Sbjct 242 NALGKAALNLSLGGSFSQAN----NDAVTRAQEAGIFVAVAAGNDNRDARNYSP---ASA 294
Query 312 IYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASA 371
+ +S+T +S S + Y+ G+ + + T + +GTS ++
Sbjct 295 PAVCTAASSTIDDQKSSFSNWGS--IVDIYAPGSS-----ILSAAPGGGTRTLSGTSMAS 347
Query 372 PLAAGIIALTLEANKNLTW---RDMQHLVVQTSKPAHLNANDWATNGVGR 418
P G+ A L ++ R Q P N NG G+
Sbjct 348 PHVCGVGAAMLAQGVSVAQVCNRLKQIGNAVIRNPGTSTTNRLLYNGSGQ 397
>sp|C5PFR5|SU11B_COCP7 Subtilisin-like protease CPC735_047380
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_047380
PE=3 SV=1
Length=400
Score = 150 bits (378), Expect = 5e-38, Method: Composition-based stats.
Identities = 72/393 (18%), Positives = 132/393 (34%), Gaps = 49/393 (12%)
Query 34 WAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHS--RLQREP 91
+ + V + A K F N D F + ++ S + + +P
Sbjct 49 FESHVKSMAKVQKANALKRDFDNT----ADGVKFKYNINGWQAYSGKFDNKTIQSILDDP 104
Query 92 QVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSI 151
+V ++E Q R + P W L ++ G + V
Sbjct 105 RVNYIEPQRTFR--AFGWVTQDNAPS----WGLGRISHTSRGRMDYVYDSSAGENVTVYS 158
Query 152 LDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVC 211
+D G++ +HP+ G G + N ++ HGT +G +A
Sbjct 159 VDSGVDISHPEFEGRAIWGVNAADNS----------DVDQIGHGTHTSGTIAGKT----- 203
Query 212 GVGVAYNARIGGVRMLDGEVTDAVEARSLGLN--PNHIHIYSASWGPEDDGKTVDGPARL 269
GVA A+I V++LD G+N NH + + + G +R
Sbjct 204 -YGVAKMAKIVAVKVLDAGGQGTNGGIIQGINWAVNHARQNNVTGKAVMNMSFGGGLSRA 262
Query 270 AEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWY 329
EA V G V A+GN + ++ ++ ++TQ +
Sbjct 263 INEAASSAVR-----AGIFMVAAAGNNNEDARYTTP---ASARGVCAVGASTQNDLKARF 314
Query 330 SEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLT 389
S + Y+ G++ + + + + GTS +AP AG+ A+ + + K T
Sbjct 315 SNWGPT--LAVYAPGDR-----IWSAMPDGGRDVMRGTSMAAPHVAGVAAVLISSEKIGT 367
Query 390 WRDMQHLVVQTSKPAHLNAND----WATNGVGR 418
R + + + D NG G+
Sbjct 368 DRLCERIKELSVSSIQSPGADTTDKLLYNGSGQ 400
>sp|G1X8P8|SPAZ_ARTOA Cuticle-degrading serine protease OS=Arthrobotrys
oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491)
OX=756982 PE=1 SV=1
Length=409
Score = 150 bits (378), Expect = 5e-38, Method: Composition-based stats.
Identities = 70/346 (20%), Positives = 128/346 (37%), Gaps = 54/346 (16%)
Query 43 AVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAK 102
A A+ V RK F + G ++ + G K +L + P+V ++EQ
Sbjct 74 ARAHGVGRKFRFSSTG------FNGYVGGFDKATL-------QEILNSPEVDYVEQDTVV 120
Query 103 RRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAW--AQGYTGHGIVVSILDDGIEKNH 160
+ W L ++ D + + + G G V ++D GI +H
Sbjct 121 TTYAE---------QTDSTWGLDRISHEDYSAPYTYEYDETAAGAGTTVYVIDTGIRISH 171
Query 161 PDLAG-NYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNA 219
+ N A++ N D T + N HGT CAG +A GV+ A
Sbjct 172 DEFQTVNGSSRATWGFNSVDK------TDSDGNGHGTHCAGTIAGKT------YGVSKKA 219
Query 220 RIGGVRMLDGEVTDAVEARSLGLNPNHIHIY-SASWGPEDDGKTVDGPARLAEEAFFRGV 278
++ V++L + + G+N + +A+ ++ G A +
Sbjct 220 KVVAVKVLSAGGSGSTAGVVSGMN----WVAENATPNFSVASMSLGGSKSAALNTAVDAI 275
Query 279 SQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLA 338
G V A+GN ++ + + N+I ++ + + +S TL
Sbjct 276 ----FNAGITIVVAAGNENQDAKNVSPASAPNAI---TVGAIDSSNKIASFSNWG--TLI 326
Query 339 TTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA 384
++ G T+D K T++ +GTS + P AG+ A + A
Sbjct 327 DVFAPGVGVLSSWATSD---KETKTISGTSMACPHVAGLAAYYISA 369
>sp|D4CZQ4|SUB7_TRIVH Subtilisin-like protease 7 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB7 PE=3 SV=2
Length=420
Score = 150 bits (378), Expect = 6e-38, Method: Composition-based stats.
Identities = 55/323 (17%), Positives = 114/323 (35%), Gaps = 38/323 (12%)
Query 59 QIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ G H + + S H + + + V+++E+ + + Q+ P
Sbjct 71 KAMGGMKHTYRFPTGLKGYSGHFDEQMINEISKRADVKYIERDARVQINA--IEQQDNVP 128
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
W L+ V ++ + G G G ++D G + H + G GA+F +
Sbjct 129 S----WGLARVGSKEPGGTTYYYDGTAGEGSTAYVIDTGTDIQHEEFEGRATWGANFVDD 184
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVE 236
M+ N HGT +G + G GVA + + V++LD + +
Sbjct 185 ----------MDMDCNGHGTHVSGTI------GGKTFGVAKKSNVVAVKVLDCNGSGSNS 228
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
+G+ ++ G A ++QG G A+GN
Sbjct 229 GVIMGMEWATKDAQQKGADKAVANMSLGGAFSQASNDAAAAIAQG----GVFLAVAAGND 284
Query 297 GREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL 356
+ + + +++++T+ +S + Y+ G+ +T+
Sbjct 285 NVDAADSSP---ASEPSICTVAASTEQDGKADFSNFG--QVVDVYAPGDS-----ITSAK 334
Query 357 RQKCTESHTGTSASAPLAAGIIA 379
++ +GTS + P AG+ A
Sbjct 335 PGGGSQVLSGTSMATPHVAGLGA 357
>sp|Q5JIZ5|TKSP_THEKO Subtilisin-like serine protease OS=Thermococcus
kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
OX=69014 GN=TK1689 PE=1 SV=1
Length=663
Score = 154 bits (388), Expect = 8e-38, Method: Composition-based stats.
Identities = 83/449 (18%), Positives = 154/449 (34%), Gaps = 77/449 (17%)
Query 128 TQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYT 187
+ + W GY G GI + I+D GI+ +HPDL G F P
Sbjct 145 SAAQVMATNMWNLGYDGSGITIGIIDTGIDASHPDLQGKVIGWVDFVNGKTTP------- 197
Query 188 QMNDNRHGTRCAGEVAAVANNGVCGV-GVAYNARIGGVRMLDGEVTDAVEARSLGL---- 242
+DN HGT A A G+A A++ G+++L+G+ + ++ G+
Sbjct 198 -YDDNGHGTHVASIAAGTGAASNGKYKGMAPGAKLVGIKVLNGQGSGSISDIINGVDWAV 256
Query 243 ---NPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGRE 299
+ I + + S G D ++ A+ G + V A+GN G
Sbjct 257 QNKDKYGIKVINLSLGSSQSSDGTDSLSQAVNNAWD---------AGLVVVVAAGNSGPN 307
Query 300 HDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVT-----T 354
+ + +++ + ++ + +S + I+ T
Sbjct 308 KYTVGSPAAAS--KVITVGAVDKYDVITDFSSRGPTADNRLKPEVVAPGNWIIAARASGT 365
Query 355 DLRQKCTESHT---GTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDW 411
+ Q + +T GTS + P AGI AL L+A+ + T ++ +++T+
Sbjct 366 SMGQPINDYYTAAPGTSMATPHVAGIAALLLQAHPSWTPDKVKTALIETADIVKP----- 420
Query 412 ATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTV 471
+YG G ++A A T + T+
Sbjct 421 -----DEIADIAYGAGRVNAYKA----------AYYDNYAKLTFTGYVSNKGSQSHQFTI 465
Query 472 TACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDW 531
+ A L + DL ++L P G DYS + +
Sbjct 466 SGA----------GFVTATLYWDNSG-SDLDLYLYDPNG--------NQVDYSYTAY--Y 504
Query 532 AFMTTHSWDEDPSGEWVLEIENTSEANNY 560
F ++ +G W +++ + S + NY
Sbjct 505 GFEKVGYYN-PTAGTWTIKVVSYSGSANY 532
>sp|D4APA9|SUB7_ARTBC Subtilisin-like protease 7 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB7
PE=1 SV=2
Length=420
Score = 149 bits (377), Expect = 1e-37, Method: Composition-based stats.
Identities = 54/323 (17%), Positives = 115/323 (36%), Gaps = 38/323 (12%)
Query 59 QIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ G H + + S H + + + V+++E+ + + Q+ P
Sbjct 71 KAMGGMKHTYRFPTGLKGYSGHFDEQMINEISKRADVKYIERDARVQINA--IEQQDNVP 128
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
W L+ V ++ + G G G ++D G + H + G GA+F +
Sbjct 129 S----WGLARVGSKEPGGTTYYYDGTAGEGSTAYVIDTGTDIQHEEFEGRATWGANFVDD 184
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVE 236
M+ N HGT +G + G GVA + + V++LD + +
Sbjct 185 ----------MDMDCNGHGTHVSGTI------GGKTFGVAKKSNVVAVKVLDCNGSGSNS 228
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
+G+ ++ G A +++G G A+GN
Sbjct 229 GVIMGMEWATKDAQQKGADKAVANMSLGGAFSQASNDAAAAIAKG----GVFLAVAAGND 284
Query 297 GREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL 356
+ + + +++++T+ + +S + Y+ G+ +T+
Sbjct 285 NVDAADSSP---ASEPSICTVAASTEQDSKADFSNFG--QVVDVYAPGDS-----ITSAK 334
Query 357 RQKCTESHTGTSASAPLAAGIIA 379
++ +GTS + P AG+ A
Sbjct 335 PGGGSQVLSGTSMATPHVAGLGA 357
>sp|C5P1W9|SU11A_COCP7 Subtilisin-like protease CPC735_035780
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_035780
PE=3 SV=1
Length=403
Score = 149 bits (376), Expect = 1e-37, Method: Composition-based stats.
Identities = 76/367 (21%), Positives = 132/367 (36%), Gaps = 46/367 (13%)
Query 62 GDYYHFWHRGVTKRSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFP 119
G H + R + S R + R+ V ++E T + +P P
Sbjct 73 GGLKHVY-RIDGWQGYSGSFARETIDRILENDDVDYVEPDRRVHLTA--LTTQPNAPS-- 127
Query 120 QQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQD 179
W L ++ R+ G GI +D GI+ NHPD G G +
Sbjct 128 --WGLGRISHRNNGNSNFVYDDRAGEGITFYGVDTGIDINHPDFGGRAVWGTN------- 178
Query 180 PDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARS 239
+ + + HGT AG VA + G+A A++ V++L T
Sbjct 179 ---TAGGSDSDGHGHGTHTAGTVAGAS------YGIAKKAKLVAVKVLSEGGTGQWSGII 229
Query 240 LGLNPNHIHI-YSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG-- 296
G+N + H + + G ++ G + G A+GN
Sbjct 230 EGINWSVNHARANNALGKAVMNMSLGGR----LSTSVNQATTRAQRAGIFIAVAAGNEDP 285
Query 297 GREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL 356
+ D+ N ++ +++++T+ +S S + Y+ G IV+T
Sbjct 286 SVQSDAANTSP-ASAEDVCTVAASTEQDGRASFSNWGS--MVEIYAPG----TNIVSTT- 337
Query 357 RQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVV-----QTSKPAHLNANDW 411
T +GTS +AP AG+ A + A++ ++ ++ +V Q S P N
Sbjct 338 PGGNTGKMSGTSMAAPHVAGVGAAIM-ASEGISPSEVCSRLVEIGLEQISNPGSGTTNKL 396
Query 412 ATNGVGR 418
N GR
Sbjct 397 LYNNSGR 403
>sp|Q5VJ71|SUB7_TRIVC Subtilisin-like protease 7 OS=Trichophyton
verrucosum OX=63417 GN=SUB7 PE=3 SV=1
Length=400
Score = 149 bits (375), Expect = 1e-37, Method: Composition-based stats.
Identities = 55/323 (17%), Positives = 114/323 (35%), Gaps = 38/323 (12%)
Query 59 QIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ G H + + S H + + + V+++E+ + + Q+ P
Sbjct 71 KAMGGMKHTYRFPTGLKGYSGHFDEQMINEISKRADVKYIERDARVQINA--IEQQDNVP 128
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
W L+ V ++ + G G G ++D G + H + G GA+F +
Sbjct 129 S----WGLARVGSKEPGGTTYYYDGTAGEGSTAYVIDTGTDIQHEEFEGRATWGANFVDD 184
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVE 236
M+ N HGT +G + G GVA + + V++LD + +
Sbjct 185 ----------MDMDCNGHGTHVSGTI------GGKTFGVAKKSNVVAVKVLDCNGSGSNS 228
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
+G+ ++ G A ++QG G A+GN
Sbjct 229 GVIMGMEWATKDAQQKGADKAVANMSLGGAFSQASNDAAAAIAQG----GVFLAVAAGND 284
Query 297 GREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL 356
+ + + +++++T+ +S + Y+ G+ +T+
Sbjct 285 NVDAADSSP---ASEPSICTVAASTEQDGKADFSNFG--QVVDVYAPGDS-----ITSAK 334
Query 357 RQKCTESHTGTSASAPLAAGIIA 379
++ +GTS + P AG+ A
Sbjct 335 PGGGSQVLSGTSMATPHVAGLGA 357
>sp|C5PCX1|SUB7B_COCP7 Subtilisin-like protease CPC735_015300
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_015300
PE=3 SV=1
Length=398
Score = 148 bits (374), Expect = 2e-37, Method: Composition-based stats.
Identities = 58/314 (18%), Positives = 111/314 (35%), Gaps = 55/314 (18%)
Query 80 HRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWA 139
R + + P V ++E R T ++ ++P P W L V+ ++
Sbjct 91 DRDTIKDISQSPDVAFIEHDHVVRLT--ELVEQPDAP----TWGLGRVSHQEPGNMDYVY 144
Query 140 QGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
G G+ +D G++ HPD G G++ +D + N HGT
Sbjct 145 DDTAGDGVWAYDIDTGVDIEHPDFEGRAVWGSNHVDDD----------DTDGNGHGTHVG 194
Query 200 GEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIH----------I 249
G + G GVA RI V++LD + + G++ + H +
Sbjct 195 GTI------GSLTYGVAKKVRIIAVKVLDARGSGSNSGVIAGIDWSVNHAMENNVAERAV 248
Query 250 YSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYT 309
+ S G + A V G A+GN + ++ +
Sbjct 249 INLSLG--------GARSDTTNMAVANAVQAGLH-----VAVAAGNDNEDAENSSP---A 292
Query 310 NSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSA 369
+ +++++ +S S + Y+ G + + + T++ +GTS
Sbjct 293 SEPTVCTVAASNINDQKASFSNFGS--VVDIYAPGEE-----ILSLAPGGGTQTLSGTSM 345
Query 370 SAPLAAGIIALTLE 383
+AP AG+ A +
Sbjct 346 AAPHIAGMGAYLIA 359
>sp|Q64K36|SUB7_ARTBE Subtilisin-like protease 7 OS=Arthroderma
benhamiae OX=63400 GN=SUB7 PE=1 SV=1
Length=400
Score = 148 bits (373), Expect = 2e-37, Method: Composition-based stats.
Identities = 54/323 (17%), Positives = 115/323 (36%), Gaps = 38/323 (12%)
Query 59 QIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ G H + + S H + + + V+++E+ + + Q+ P
Sbjct 71 KAMGGMKHTYRFPTGLKGYSGHFDEQMINEISKRADVKYIERDARVQINA--IEQQDNVP 128
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
W L+ V ++ + G G G ++D G + H + G GA+F +
Sbjct 129 S----WGLARVGSKEPGGTTYYYDGTAGEGSTAYVIDTGTDIQHEEFEGRATWGANFVDD 184
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVE 236
M+ N HGT +G + G GVA + + V++LD + +
Sbjct 185 ----------MDMDCNGHGTHVSGTI------GGKTFGVAKKSNVVAVKVLDCNGSGSNS 228
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
+G+ ++ G A +++G G A+GN
Sbjct 229 GVIMGMEWATKDAQQKGADKAVANMSLGGAFSQASNDAAAAIAKG----GVFLAVAAGND 284
Query 297 GREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL 356
+ + + +++++T+ + +S + Y+ G+ +T+
Sbjct 285 NVDAADSSP---ASEPSICTVAASTEQDSKADFSNFG--QVVDVYAPGDS-----ITSAK 334
Query 357 RQKCTESHTGTSASAPLAAGIIA 379
++ +GTS + P AG+ A
Sbjct 335 PGGGSQVLSGTSMATPHVAGLGA 357
>sp|Q8NID9|SUB7_TRIRU Subtilisin-like protease 7 OS=Trichophyton
rubrum OX=5551 GN=SUB7 PE=2 SV=1
Length=400
Score = 147 bits (371), Expect = 4e-37, Method: Composition-based stats.
Identities = 54/323 (17%), Positives = 115/323 (36%), Gaps = 38/323 (12%)
Query 59 QIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ G H ++ + S H + + + V+++E+ + + Q+ P
Sbjct 71 KAMGGMKHTYNFPTGLKGYSGHFDEQMINEISKRADVKYIERDARVQINA--IEQQDNVP 128
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
W L+ V ++ + G G ++D G + H + G GA+F +
Sbjct 129 S----WGLARVGSKEPGGTTYYYDSTAGEGSTAYVIDTGTDIQHEEFEGRATWGANFVDD 184
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVE 236
M+ N HGT +G + G GVA + + V++LD + +
Sbjct 185 ----------MDMDCNGHGTHVSGTI------GGKTFGVAKKSNVVAVKVLDCNGSGSNS 228
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
+G+ ++ G A +++G G A+GN
Sbjct 229 GVIMGMEWATKDAQQKGADKAVANMSLGGAFSQASNDAAAAIAKG----GVFLAVAAGND 284
Query 297 GREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL 356
+ + + +I+++T+ + +S + Y+ G+ +T+
Sbjct 285 NVDAADSSP---ASEPSICTIAASTEQDSKADFSNFG--QVVDVYAPGDS-----ITSAK 334
Query 357 RQKCTESHTGTSASAPLAAGIIA 379
++ +GTS + P AG+ A
Sbjct 335 PGGGSQVLSGTSMATPHVAGLGA 357
>sp|A1XIH6|SUB7_TRIVO Subtilisin-like protease 7 OS=Trichophyton
violaceum OX=34388 GN=SUB7 PE=1 SV=1
Length=400
Score = 147 bits (370), Expect = 6e-37, Method: Composition-based stats.
Identities = 54/323 (17%), Positives = 115/323 (36%), Gaps = 38/323 (12%)
Query 59 QIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ G H ++ + S H + + + V+++E+ + + Q+ P
Sbjct 71 KAMGGMKHTYNFPTGLKGYSGHFDEQMINEISKRADVKYIERDARVQINA--IEQQDNVP 128
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
W L+ V ++ + G G ++D G + H + G GA+F +
Sbjct 129 S----WGLARVGSKEPGGTTYYYDSTAGEGSTAYVIDTGTDIQHEEFEGRATWGANFVDD 184
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVE 236
M+ N HGT +G + G GVA + + V++LD + +
Sbjct 185 ----------MDMDCNGHGTHVSGTI------GGKTFGVAKKSNVVAVKVLDCSGSGSNS 228
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
+G+ ++ G A +++G G A+GN
Sbjct 229 GVIMGMEWATKDAQQKGADKAVANMSLGGAFSQASNDAAAAIAKG----GVFLAVAAGND 284
Query 297 GREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL 356
+ + + +I+++T+ + +S + Y+ G+ +T+
Sbjct 285 NVDAADSSP---ASEPSICTIAASTEQDSKADFSNFG--QVVDVYAPGDS-----ITSAK 334
Query 357 RQKCTESHTGTSASAPLAAGIIA 379
++ +GTS + P AG+ A
Sbjct 335 PGGGSQVLSGTSMATPHVAGLGA 357
>sp|G3FNQ9|SPAZ_ORBOL Cuticle-degrading serine protease OS=Orbilia
oligospora OX=2813651 PE=1 SV=2
Length=426
Score = 147 bits (371), Expect = 6e-37, Method: Composition-based stats.
Identities = 71/346 (21%), Positives = 128/346 (37%), Gaps = 54/346 (16%)
Query 43 AVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAK 102
A A+ V RK F + G ++ + G K +L + P+V ++EQ
Sbjct 74 ARAHGVGRKFRFSSTG------FNGYVGGFDKATL-------QEILNSPEVDYVEQDTVV 120
Query 103 RRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAW--AQGYTGHGIVVSILDDGIEKNH 160
+ W L ++ D + + + G G V ++D GI +H
Sbjct 121 TTYAE---------QTDSTWGLDRISHEDYSAPYTYEYDETAAGAGTTVYVIDTGIRISH 171
Query 161 PDLAG-NYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNA 219
+ N A++ N D T + N HGT CAG +A GV+ A
Sbjct 172 DEFQTVNGSSRATWGFNSVDK------TDSDGNGHGTHCAGTIAGKT------YGVSKKA 219
Query 220 RIGGVRMLDGEVTDAVEARSLGLNPNHIHIY-SASWGPEDDGKTVDGPARLAEEAFFRGV 278
++ V++L + + G+N + +A+ ++ G A A +
Sbjct 220 KVVAVKVLSAGGSGSTAGVVSGMN----WVAENATPNFSVASMSLGGSKSTALNAAVDCI 275
Query 279 SQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLA 338
G V A+GN ++ + + N+I ++ + + S TL
Sbjct 276 ----FNAGITIVVAAGNENQDAKNVSPASAPNAI---TVGAIDSSNKIASLSNWG--TLI 326
Query 339 TTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA 384
++ G T+D K T++ +GTS + P AG+ A + A
Sbjct 327 DVFAPGVGVLSSWATSD---KETKTISGTSMACPHVAGLAAYYISA 369
>sp|Q9Y749|PENC1_PENCI Subtilisin-like serine protease Pen c 1
OS=Penicillium citrinum OX=5077 PE=1 SV=1
Length=397
Score = 145 bits (366), Expect = 1e-36, Method: Composition-based stats.
Identities = 70/361 (19%), Positives = 126/361 (35%), Gaps = 66/361 (18%)
Query 33 TWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQ 92
WA + A RK+G G+ HF G+ + S + +P
Sbjct 54 EWATNVH-----ARLSRRKNGETGPGK------HFEINGLKGYTASFDESTAKDIANDPA 102
Query 93 VQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSIL 152
V+++E + T V P W L+ ++ + + G G+V +
Sbjct 103 VKYIEPDMIVNATANVVQ--SNVPS----WGLARISSKRTGTTSYTYDSTAGEGVVFYGV 156
Query 153 DDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCG 212
D GI+ +H D G G + ND + N HGT A A
Sbjct 157 DTGIDISHSDFGGRAKWGTNVVDNDN----------TDGNGHGTHTASTAAGSK------ 200
Query 213 VGVAYNARIGGVRMLDGEVTDAVEARSLGLN----------PNHIHIYSASWGPEDDGKT 262
GVA A + V++L + + G++ N ++ + S G E
Sbjct 201 YGVAKKATLVAVKVLGADGSGTNSGVISGMDWAVKDAKSRGANGKYVMNMSLGGEFSKAV 260
Query 263 VDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQ 322
D A + + G A+GN E ++ + ++ +I+++T
Sbjct 261 NDAAANVVKS-------------GIFLSVAAGN---EAENASNSSPASAAEVCTIAASTS 304
Query 323 FGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTL 382
++ S + Y+ G Q +T +++ +GTS +AP AG+ A +
Sbjct 305 TDGSASFTNFGS--VVDLYAPG-----QSITAAYPGGGSKTLSGTSMAAPHVAGVAAYLM 357
Query 383 E 383
Sbjct 358 A 358
>sp|D4DLA2|SUB3_TRIVH Subtilisin-like protease 3 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB3 PE=3 SV=1
Length=397
Score = 145 bits (365), Expect = 3e-36, Method: Composition-based stats.
Identities = 80/407 (20%), Positives = 141/407 (35%), Gaps = 51/407 (13%)
Query 26 GQKVFTNTWAVRIPGGPAVAN------SVARKHGFLN--LGQIFGDYYHFWHRGVTKRSL 77
G V N++ V + G + SVA H G + ++ R+
Sbjct 28 GNDVIPNSYIVVMKDGVTAEDFDSHISSVAATHSLNKAKRGSETVGHKDSFNINGW-RAY 86
Query 78 SPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVK 135
+ H + + ++ +V ++E + + +P P W L V+ + K
Sbjct 87 NGHFDEATIESILKDDKVNYVEHDRVVKLAA--LTTQPNAP----TWGLGRVSHKAPGNK 140
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHG 195
G GI + +D GI+ HP+ AG G + ND + N HG
Sbjct 141 DFVYDSSAGQGITIYGVDTGIDIRHPEFAGRIRWGTNTVDNDN----------TDGNGHG 190
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS-ASW 254
T AG A GVA A I V++L + + G++ S +
Sbjct 191 THTAGTFAGTT------YGVAKKANIVAVKVLSAGGSGSTSGVIKGIDWCVTDARSKNAL 244
Query 255 GPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYT 314
G ++ G +A V++ G A+GN R+ + + ++
Sbjct 245 GKAALNLSLGGS---FSQASNDAVTR-AQEAGIFVAVAAGNDNRDAKNSSP---ASAPAV 297
Query 315 LSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLA 374
+ +S+T +S T+ Y+ G+ + + T + +GTS ++P
Sbjct 298 CTAASSTIDDQKSSFSNWG--TIVDIYAPGSN-----ILSAAPGGGTRTLSGTSMASPHV 350
Query 375 AGIIALTLEANKNLTW---RDMQHLVVQTSKPAHLNANDWATNGVGR 418
G+ A L ++ R Q P N NG GR
Sbjct 351 CGVGAAMLAQGVSVAQACDRLKQIGNAVIRNPGTGTTNRLLYNGSGR 397
>sp|Q5VJ75|SUB3_TRIVC Subtilisin-like protease 3 OS=Trichophyton
verrucosum OX=63417 GN=SUB3 PE=3 SV=1
Length=397
Score = 145 bits (365), Expect = 3e-36, Method: Composition-based stats.
Identities = 80/407 (20%), Positives = 141/407 (35%), Gaps = 51/407 (13%)
Query 26 GQKVFTNTWAVRIPGGPAVAN------SVARKHGFLN--LGQIFGDYYHFWHRGVTKRSL 77
G V N++ V + G + SVA H G + ++ R+
Sbjct 28 GNDVIPNSYIVVMKDGVTAEDFDSHISSVAATHSLNKAKRGSETVGHKDSFNINGW-RAY 86
Query 78 SPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVK 135
+ H + + ++ +V ++E + + +P P W L V+ + K
Sbjct 87 NGHFDEATIESILKDDKVNYVEHDRVVKLAA--LTTQPNAP----TWGLGRVSHKAPGNK 140
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHG 195
G GI + +D GI+ HP+ AG G + ND + N HG
Sbjct 141 DFVYDSSAGQGITIYGVDTGIDIRHPEFAGRIRWGTNTVDNDN----------TDGNGHG 190
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS-ASW 254
T AG A GVA A I V++L + + G++ S +
Sbjct 191 THTAGTFAGTT------YGVAKKANIVAVKVLSAGGSGSTSGVIKGIDWCVTDARSKNAL 244
Query 255 GPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYT 314
G ++ G +A V++ G A+GN R+ + + ++
Sbjct 245 GKAALNLSLGGS---FSQASNDAVTR-AQEAGIFVAVAAGNDNRDAKNSSP---ASAPAV 297
Query 315 LSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLA 374
+ +S+T +S T+ Y+ G+ + + T + +GTS ++P
Sbjct 298 CTAASSTIDDQKSSFSNWG--TIVDIYAPGSN-----ILSAAPGGGTRTLSGTSMASPHV 350
Query 375 AGIIALTLEANKNLTW---RDMQHLVVQTSKPAHLNANDWATNGVGR 418
G+ A L ++ R Q P N NG GR
Sbjct 351 CGVGAAMLAQGVSVAQACDRLKQIGNAVIRNPGTGTTNRLLYNGSGR 397
>sp|Q64K34|SUB3_ARTBE Subtilisin-like protease 3 OS=Arthroderma
benhamiae OX=63400 GN=SUB3 PE=1 SV=1
Length=397
Score = 145 bits (365), Expect = 3e-36, Method: Composition-based stats.
Identities = 80/407 (20%), Positives = 141/407 (35%), Gaps = 51/407 (13%)
Query 26 GQKVFTNTWAVRIPGGPAVAN------SVARKHGFLN--LGQIFGDYYHFWHRGVTKRSL 77
G V N++ V + G + SVA H G + ++ R+
Sbjct 28 GNDVIPNSYIVVMKDGVTAEDFDSHISSVAATHSLNKAKRGSETVGHKDSFNINGW-RAY 86
Query 78 SPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVK 135
+ H + + ++ +V ++E + + +P P W L V+ + K
Sbjct 87 NGHFDEATIESILKDDKVNYVEHDRVVKLAA--LTTQPNAP----TWGLGRVSHKAPGNK 140
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHG 195
G GI + +D GI+ HP+ AG G + ND + N HG
Sbjct 141 DFVYDSSAGQGITIYGVDTGIDIRHPEFAGRIRWGTNTVDNDN----------TDGNGHG 190
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS-ASW 254
T AG A GVA A I V++L + + G++ S +
Sbjct 191 THTAGTFAGTT------YGVAKKANIVAVKVLSAGGSGSTSGVIKGIDWCVTDARSKNAL 244
Query 255 GPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYT 314
G ++ G +A V++ G A+GN R+ + + ++
Sbjct 245 GKAALNLSLGGS---FSQASNDAVTR-AQEAGIFVAVAAGNDNRDAKNSSP---ASAPAV 297
Query 315 LSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLA 374
+ +S+T +S T+ Y+ G+ + + T + +GTS ++P
Sbjct 298 CTAASSTIDDQKSSFSNWG--TIVDIYAPGSN-----ILSAAPGGGTRTLSGTSMASPHV 350
Query 375 AGIIALTLEANKNLTW---RDMQHLVVQTSKPAHLNANDWATNGVGR 418
G+ A L ++ R Q P N NG GR
Sbjct 351 CGVGAAMLAQGVSVAQACDRLKQIGNAVIRNPGTGTTNRLLYNGSGR 397
>sp|D4AWY5|SUB3_ARTBC Subtilisin-like protease 3 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB3
PE=1 SV=1
Length=397
Score = 145 bits (365), Expect = 3e-36, Method: Composition-based stats.
Identities = 80/407 (20%), Positives = 141/407 (35%), Gaps = 51/407 (13%)
Query 26 GQKVFTNTWAVRIPGGPAVAN------SVARKHGFLN--LGQIFGDYYHFWHRGVTKRSL 77
G V N++ V + G + SVA H G + ++ R+
Sbjct 28 GNDVIPNSYIVVMKDGVTAEDFDSHISSVAATHSLNKAKRGSETVGHKDSFNINGW-RAY 86
Query 78 SPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVK 135
+ H + + ++ +V ++E + + +P P W L V+ + K
Sbjct 87 NGHFDEATIESILKDDKVNYVEHDRVVKLAA--LTTQPNAP----TWGLGRVSHKAPGNK 140
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHG 195
G GI + +D GI+ HP+ AG G + ND + N HG
Sbjct 141 DFVYDSSAGQGITIYGVDTGIDIRHPEFAGRIRWGTNTVDNDN----------TDGNGHG 190
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS-ASW 254
T AG A GVA A I V++L + + G++ S +
Sbjct 191 THTAGTFAGTT------YGVAKKANIVAVKVLSAGGSGSTSGVIKGIDWCVTDARSKNAL 244
Query 255 GPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYT 314
G ++ G +A V++ G A+GN R+ + + ++
Sbjct 245 GKAALNLSLGGS---FSQASNDAVTR-AQEAGIFVAVAAGNDNRDAKNSSP---ASAPAV 297
Query 315 LSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLA 374
+ +S+T +S T+ Y+ G+ + + T + +GTS ++P
Sbjct 298 CTAASSTIDDQKSSFSNWG--TIVDIYAPGSN-----ILSAAPGGGTRTLSGTSMASPHV 350
Query 375 AGIIALTLEANKNLTW---RDMQHLVVQTSKPAHLNANDWATNGVGR 418
G+ A L ++ R Q P N NG GR
Sbjct 351 CGVGAAMLAQGVSVAQACDRLKQIGNAVIRNPGTGTTNRLLYNGSGR 397
>sp|A1XIH5|SUB7_TRISD Subtilisin-like protease 7 OS=Trichophyton
soudanense OX=69891 GN=SUB7 PE=1 SV=1
Length=400
Score = 144 bits (364), Expect = 3e-36, Method: Composition-based stats.
Identities = 53/323 (16%), Positives = 114/323 (35%), Gaps = 38/323 (12%)
Query 59 QIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ G H ++ + S H + + + V+++E+ + + Q+ P
Sbjct 71 KAMGGMKHTYNFPTGLKGYSGHFDEQMINEISKRADVKYIERDARVQINA--IEQQDNVP 128
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
W L+ V ++ + G G ++D G + H + G GA+F +
Sbjct 129 S----WGLARVGSKEPGGTTYYYDSTAGEGSTAYVIDTGTDIQHEEFEGRATWGANFVDD 184
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVE 236
M+ N HGT +G + G GVA + + V++LD + +
Sbjct 185 ----------MDMDCNGHGTHVSGTI------GGKTFGVAKKSNVVAVKVLDCNGSGSNS 228
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
+G+ ++ G A +++G G A+GN
Sbjct 229 GVIMGMEWATKDAQQKGADKAVANMSLGGAFSQASNDAAAAIAKG----GVFLAVAAGND 284
Query 297 GREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL 356
+ + + +I+++T+ + +S + Y+ G+ +T+
Sbjct 285 NVDAADSSP---ASEPSICTIAASTEQDSKADFSNFG--QVVDVYAPGDS-----ITSAK 334
Query 357 RQKCTESHTGTSASAPLAAGIIA 379
++ +G S + P AG+ A
Sbjct 335 PGGGSQVLSGISMATPHVAGLGA 357
>sp|A1XIH3|SUB7_TRIEQ Subtilisin-like protease 7 OS=Trichophyton
equinum OX=63418 GN=SUB7 PE=1 SV=1
Length=401
Score = 144 bits (362), Expect = 6e-36, Method: Composition-based stats.
Identities = 62/367 (17%), Positives = 125/367 (34%), Gaps = 43/367 (12%)
Query 59 QIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ G + ++ + S H + + V+++E+ + + Q+ P
Sbjct 71 KAMGGMKYTYNFPTGLKGYSGHFDEQMIKEISKRADVKYIERDARVQINA--IEQQDNVP 128
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
W L+ V R+ + G G I+D G + H + G A++ N
Sbjct 129 S----WGLARVGSREPGGTTYYYDSTAGEGTTAYIIDTGTDIQHEEFDG---GRATWGEN 181
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVE 236
D M+ N HGT +G V GVA + I V++LD + +
Sbjct 182 FADDM------DMDCNGHGTHVSGTVGGRT------FGVAKKSNIVAVKVLDCNGSGSNS 229
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
+G+ S ++ G + +++G G A+GN
Sbjct 230 GVIMGMQWATEDAQSKGADKAVVNMSLGGAFSQTSNDAAKAIAEG----GVFLAVAAGND 285
Query 297 GREHDSCNCDGYTNSIYTL-SISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTD 355
+ + S ++ +++++T+ +S + Y+ G+ +T+
Sbjct 286 NVDA----AEASPASEPSICTVAASTEQDGKADFSNFG--QVVDVYAPGDG-----ITSA 334
Query 356 LRQKCTESHTGTSASAPLAAGIIALTL----EANKNLTWRDMQHLVVQTSKPAHLNANDW 411
++ +GTS ++P AG+ A + L Q + P +
Sbjct 335 KPGGGSQVLSGTSMASPHVAGLAAYLIGLGKGGGPQLCDTIKQMAIDVIQNPGSSTTSKL 394
Query 412 ATNGVGR 418
NG G
Sbjct 395 INNGSGM 401
>sp|A1XIH4|SUB7_TRITO Subtilisin-like protease 7 OS=Trichophyton
tonsurans OX=34387 GN=SUB7 PE=1 SV=1
Length=401
Score = 143 bits (361), Expect = 8e-36, Method: Composition-based stats.
Identities = 61/368 (17%), Positives = 124/368 (34%), Gaps = 45/368 (12%)
Query 59 QIFGDYYHFWHRGVTKRSLSPHRPRH--SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ G + ++ + S H + + V+++E+ + + Q+ P
Sbjct 71 KAMGGMKYTYNFPTGLKGYSGHFDEQMIKEISKRADVKYIERDARVQINA--IEQQDNVP 128
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLA-GNYDPGASFDV 175
W L+ V R+ + G G I+D G + H + G G +F
Sbjct 129 S----WGLARVGSREPGGTTYYYDSTAGEGTTAYIIDTGTDIQHEEFDGGRATWGENFVD 184
Query 176 NDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAV 235
+ M+ N HGT +G V GVA + I V++LD + +
Sbjct 185 D----------MDMDCNGHGTHVSGTVGGRT------FGVAKKSNIVAVKVLDCNGSGSN 228
Query 236 EARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGN 295
+G+ S ++ G + +++G G A+GN
Sbjct 229 SGVIMGMQWATEDAQSKGADKAVVNMSLGGAFSQTSNDAAKAIAEG----GVFLAVAAGN 284
Query 296 GGREHDSCNCDGYTNSIYTL-SISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTT 354
+ + S ++ +++++T+ +S + Y+ G+ +T+
Sbjct 285 DNVDA----AEASPASEPSICTVAASTEQDGKADFSNFG--QVVDVYAPGDG-----ITS 333
Query 355 DLRQKCTESHTGTSASAPLAAGIIALTL----EANKNLTWRDMQHLVVQTSKPAHLNAND 410
++ +GTS ++P AG+ A + L Q + P +
Sbjct 334 AKPGGGSQVLSGTSMASPHVAGLAAYLIGLGKGGGPQLCDTIKQMAIDVIQNPGSSTTSK 393
Query 411 WATNGVGR 418
NG G
Sbjct 394 LINNGSGM 401
>sp|Q9URR2|PEN13_PENRB Subtilisin-like serine protease Pen ch
13.0101 OS=Penicillium rubens OX=1108849 PE=1 SV=1
Length=397
Score = 143 bits (359), Expect = 1e-35, Method: Composition-based stats.
Identities = 69/361 (19%), Positives = 123/361 (34%), Gaps = 66/361 (18%)
Query 33 TWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQ 92
WA + A RK+G G+ HF G+ + S + +P
Sbjct 54 EWATNVH-----ARLSRRKNGETGPGK------HFEINGLKGYTASFDENTAKDIANDPA 102
Query 93 VQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSIL 152
V+++E + T V P W L+ ++ + + G G+V +
Sbjct 103 VKYIEPDMIVNATANVVQ--SNVPS----WGLARISSKRTGTTSYTYDSTAGEGVVFYGV 156
Query 153 DDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCG 212
D GI+ +H D G G + ND + N HGT A A
Sbjct 157 DTGIDISHSDFGGRAKWGTNVVDNDN----------TDGNGHGTHTASTAAGSK------ 200
Query 213 VGVAYNARIGGVRMLDGEVTDAVEARSLGLN----------PNHIHIYSASWGPEDDGKT 262
GVA A + V++L + + G++ N ++ + S G E
Sbjct 201 YGVAKKATLVAVKVLGADGSGTNSGVISGMDWAVKDAKSRGANGKYVMNTSLGGEFSKAV 260
Query 263 VDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQ 322
D A + + G A+GN + + + +I+++T
Sbjct 261 NDAAANVVKS-------------GIFLSVAAGNEAENASNSSPASAAEAC---TIAASTS 304
Query 323 FGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTL 382
++ S + Y+ G Q +T +++ +GTS +AP AG+ A +
Sbjct 305 TDGSASFTNFGS--VVDLYAPG-----QSITAAYPGGGSKTLSGTSMAAPHVAGVAAYLM 357
Query 383 E 383
Sbjct 358 A 358
>sp|C5FQI3|SUB6_ARTOC Subtilisin-like protease 6 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB6
PE=3 SV=1
Length=406
Score = 143 bits (359), Expect = 2e-35, Method: Composition-based stats.
Identities = 68/346 (20%), Positives = 121/346 (35%), Gaps = 55/346 (16%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ + V ++E + T + ++ P W LS ++ ++ + G G
Sbjct 102 IAKNDDVDFIEPDY--KVTLSSITEQKDVPS----WGLSRLSTKEPGGTTYFYDESAGEG 155
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I+D GI+ N+ D G G +F + + N HGT AG V
Sbjct 156 TTAYIVDTGIDVNNGDFGGRAKWGNNFV----------DHQDTDCNGHGTHVAGTV---- 201
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGK----- 261
G GVA + V++LD + + G+ + AS G K
Sbjct 202 --GGKNFGVAKKTNLIAVKVLDCNGSGSNSGVIKGMEW---VMRDASGGGNSTSKASKSV 256
Query 262 ---TVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSIS 318
++ GP A + +S G A+GN + D + +++
Sbjct 257 MNMSLGGPRSEATNRAAKAIS----DAGIFLAVAAGNDNADSQH---DSPASEPSVCTVA 309
Query 319 SATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGII 378
++ + +S + ++ G +T+D T +GTS ++P GI
Sbjct 310 ASAEDDTKASFSNWGQA--VDVFAPGMH-----ITSDKPGNGTAVLSGTSMASPHVCGIG 362
Query 379 ALTLEANKNL------TWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
A + K T +DM V++ P N NG G+
Sbjct 363 AYLIGLGKKGGPGLCDTIKDMARPVIK--NPGQGTTNKLIYNGSGK 406
>sp|D4B5N1|SUB9_ARTBC Subtilisin-like protease 9 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB9
PE=3 SV=1
Length=402
Score = 141 bits (356), Expect = 3e-35, Method: Composition-based stats.
Identities = 69/405 (17%), Positives = 133/405 (33%), Gaps = 46/405 (11%)
Query 17 LVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRS 76
+V+ + ++ + WA +I + G L F G+ S
Sbjct 39 VVMKSTISEAEFQTHQAWASKIHRRN-LGERDGTLGGLDGLKTTFE------FEGLKGYS 91
Query 77 LSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKA 136
+ + + R P V ++E + + + P W L ++ +
Sbjct 92 GAFDKRTIELISRNPAVDYVEVDRVVKLDA--ITTQRNAPS----WGLGRISHKSAGSSD 145
Query 137 AWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGT 196
G GI + +D GI+ HP+ +G G + N+ + N HGT
Sbjct 146 FVFDDSAGSGITIYGVDTGIDIKHPEFSGRATWGTNTVDNE----------DTDQNGHGT 195
Query 197 RCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGP 256
AG A G+A A + V++L+ + T + G+ H A
Sbjct 196 HTAGTFAGAT------YGIAKKANVIAVKVLNAQGTGSTSGVIQGIQWCTDH---AGRNG 246
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
++ + F V++ G A+GN G + + ++ +
Sbjct 247 LRGKAAMNLSLGIRGSTVFNRVAEAAQQSGIFLAVAAGNDGTDAAQFSP---ASARGVCT 303
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAG 376
++ +S S + Y G IV+ + T + +GTS ++P G
Sbjct 304 AAATNSQDAATSWSNYGS--VVAVYGPGA----DIVSAYPNED-TATLSGTSMASPHVCG 356
Query 377 IIALTLE---ANKNLTWRDMQHLVVQTSKPAHLN-ANDWATNGVG 417
+ A + + ++ L V++ N NG G
Sbjct 357 VGAYLMALEGIGPDKVCDRIKELAVESVTNQKPNTTRKLLYNGSG 401
>sp|C5P6D1|SUB2A_COCP7 Subtilisin-like protease CPC735_023170
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_023170
PE=3 SV=1
Length=406
Score = 141 bits (356), Expect = 4e-35, Method: Composition-based stats.
Identities = 73/353 (21%), Positives = 118/353 (33%), Gaps = 43/353 (12%)
Query 76 SLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLN 133
+ S R + ++ P V+ +E Y + + ++ R++
Sbjct 87 AYSGSFDRETIEEIRSHPNVESVEPDSM-------AYVTELIEQRNATYGPRRISHREIP 139
Query 134 V--KAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND 191
+ W G G V I+D GI K H D G PG + D +
Sbjct 140 TGDNSYWYDSKAGEGSFVYIMDTGINKAHVDFEGRAIPGVNLHDVAFD----------DT 189
Query 192 NRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS 251
+ HG+ CAG G GVA A I V++ A SL + + +
Sbjct 190 HGHGSHCAGIA------GSKTYGVAKKATIVDVKVFTRGGG----AWSLLMGGLDWSVKN 239
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
+ V + G V ASGN GR+ + S
Sbjct 240 ITGEDRQAKSAVSISISGPTNQAMNNAVKAAVEAGVTVVVASGNDGRDAGRNSPGSAPES 299
Query 312 IYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQK-CTESHTGTSAS 370
I SI+S +S SS G I++T + T + +GTS +
Sbjct 300 ITVGSINSRRGMDTRSSFSNYGSSVAIHAPGEG------IISTYKGSRDATANMSGTSMA 353
Query 371 APLAAGIIALTLEANKNLTWRDMQHLVVQTS-----KPAHLNANDWATNGVGR 418
AP AG+IA + + +++ + + +AN A NG G+
Sbjct 354 APHVAGLIAYLQSIHDLPDPAAARRKLLELATSDKIQDVRGSANKLAYNGSGK 406
>sp|R4IR27|ASES_SARSR Subtilisin-like serine protease AsES OS=Sarocladium
strictum OX=5046 GN=AsES PE=1 SV=1
Length=388
Score = 141 bits (354), Expect = 5e-35, Method: Composition-based stats.
Identities = 58/324 (18%), Positives = 101/324 (31%), Gaps = 39/324 (12%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
H + S L+ +P V ++EQ W L
Sbjct 65 KHIYKGAFKGFSGKIDAKTLELLRDDPSVDFIEQDAIVTLAAYTTQASAP-------WGL 117
Query 125 SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQP 184
+ ++ R G G I+D GI+ NHP+ G S+
Sbjct 118 ARISTRQRGPTGYTYDDSAGAGTCSYIIDTGIQANHPNFGGRAFQLVSY----------- 166
Query 185 RYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNP 244
+ + + N HGT AG + G GVA + GV++L + + G+N
Sbjct 167 QGSNADGNGHGTHVAGTI------GSTTYGVAKRTTLLGVKVLSDSGSGSTSGIIAGINY 220
Query 245 NHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCN 304
S S +G + A ++ A+GN + + +
Sbjct 221 VVSDSRSRS---CPNGSVANMSLGGGYSASLNSAAKSLIDNNIFLAVAAGNENQNAANVS 277
Query 305 CDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESH 364
+ ++ + T +S S I++T + T +
Sbjct 278 P---ASEPTVCTVGATTSADAKASFSNYGSGVDIFAPGQ------SILSTWI-GSSTNTI 327
Query 365 TGTSASAPLAAGIIALT--LEANK 386
+GTS ++P AG+ A LE
Sbjct 328 SGTSMASPHIAGLAAYLAGLEGFP 351
>sp|Q69F56|SUB3_TRIRU Subtilisin-like protease 3 OS=Trichophyton
rubrum OX=5551 GN=SUB3 PE=1 SV=1
Length=397
Score = 141 bits (354), Expect = 5e-35, Method: Composition-based stats.
Identities = 79/407 (19%), Positives = 141/407 (35%), Gaps = 51/407 (13%)
Query 26 GQKVFTNTWAVRIPGGPAVAN------SVARKHGFLN--LGQIFGDYYHFWHRGVTKRSL 77
G V N++ V + G + SVA H G + ++ R+
Sbjct 28 GNDVIPNSYIVVMKDGVTAEDFDSHISSVAATHSLNKAKRGSETVGHKDSFNINGW-RAY 86
Query 78 SPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVK 135
+ H + + ++ +V ++E + + +P P W L V+ + K
Sbjct 87 NGHFDEATIESILKDDKVNYVEHDRVVKLAA--LTTQPNAP----TWGLGRVSHKAPGNK 140
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHG 195
G GI + +D GI+ +H + AG G + ND + N HG
Sbjct 141 DFVYDSSAGQGITIYGVDTGIDIHHSEFAGRIRWGTNTVDNDN----------TDGNGHG 190
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYS-ASW 254
T AG A GVA A I V++L + + G++ S +
Sbjct 191 THTAGTFAGTT------YGVAKKANIVAVKVLSAGGSGSTSGVIKGIDWCVTDARSKNTL 244
Query 255 GPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYT 314
G ++ G +A V++ G A+GN R+ + + ++
Sbjct 245 GKAALNLSLGGS---FSQASNDAVTR-AQEAGIFVAVAAGNDNRDAKNSSP---ASAPAV 297
Query 315 LSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLA 374
+ +S+T +S T+ Y+ G+ + + T + +GTS ++P
Sbjct 298 CTAASSTIDDQKSSFSNWG--TIVDIYAPGSN-----ILSAAPGGGTRTLSGTSMASPHV 350
Query 375 AGIIALTLEANKNLTW---RDMQHLVVQTSKPAHLNANDWATNGVGR 418
G+ A L ++ R Q P N NG GR
Sbjct 351 CGVGAAMLAQGVSVAQACNRLKQIGNAVIRNPGTGTTNRLLYNGSGR 397
>sp|E4UTU7|SUB9_ARTGP Subtilisin-like protease 9 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB9
PE=3 SV=1
Length=402
Score = 139 bits (351), Expect = 1e-34, Method: Composition-based stats.
Identities = 74/406 (18%), Positives = 138/406 (34%), Gaps = 48/406 (12%)
Query 17 LVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWH-RGVTKR 75
+V+ +A ++ + WA +I + S+ ++ G L FG + G+
Sbjct 39 VVMKSAVSEAEFQSHQAWASKIH-----SRSLGKRDGVL---DDFGGLKATFQFEGLKGY 90
Query 76 SLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVK 135
S + + + R P V ++E + ++ W L ++ R +
Sbjct 91 SGAFDKKTIELITRNPAVDYVEVDRVVKLDAISTQRDAPS------WGLGRISHRRVGSA 144
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHG 195
G GI + +D GI+ HP+ G G + V+D+D D N HG
Sbjct 145 DYVFDDSAGSGITIYGVDTGIDIRHPEFGGRAAWGTN-TVDDEDTD---------QNGHG 194
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWG 255
T AG G+A A I V++L+ + T G+ H A
Sbjct 195 THTAGTFGGAT------YGIAKKANIVAVKVLNAQGTGTTSGVIQGIQWCTDH---AGRN 245
Query 256 PEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTL 315
++ + F V++ G A+GN G + + ++
Sbjct 246 GLRGKAAMNLSLGIRGSTIFNRVAEAAQASGIFLAVAAGNDGTDAGQFSP---ASARGVC 302
Query 316 SISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAA 375
+ ++ +S S + Y G IV+ T + +GTS ++P
Sbjct 303 TAAATNSQDAATSWSNYGS--VVAVYGPGA----DIVSAYPNDD-TATLSGTSMASPHVC 355
Query 376 GIIALTLE---ANKNLTWRDMQHLVVQTSKPAHLNAN-DWATNGVG 417
G+ A + + ++ L ++ N NG G
Sbjct 356 GVGAYLMALEGIGPDTVCDRIKQLASESVTNQKPNTTKKLLYNGSG 401
>sp|D4D6Q4|SUB4_TRIVH Subtilisin-like protease 4 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB4 PE=3 SV=1
Length=399
Score = 139 bits (351), Expect = 2e-34, Method: Composition-based stats.
Identities = 66/351 (19%), Positives = 121/351 (34%), Gaps = 44/351 (13%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R H R + + + +V ++EQ R + + W L V+ R
Sbjct 86 RGYHGHFDRDTLEEILNDSKVDYVEQDQVVRISGLVTQRSAPS------WGLGRVSHRQA 139
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
+ G G+ + +D GI+ NH D G G + D + +
Sbjct 140 GSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGRARWGTNTADRDN----------ADRH 189
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSA 252
HGT A A A G+A NA I V++L + + + G+N +
Sbjct 190 GHGTHTASTFAGTA------YGIAKNANIVAVKVLGSDGSGSTSGIIAGINYCVQD--AQ 241
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
G +A V++ G A+GN R+ + + ++
Sbjct 242 QRGILGKAAMNLSLGGGFSQANNDAVTR-AQNAGIFVAVAAGNDNRDARNYSP---ASAP 297
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
+++S+T + +S + Y+ G+ I+ T + +GTS ++P
Sbjct 298 AVCTVASSTINDSKSSFSNWGP--VVDIYAPGS----DIIAARPGGGST-TMSGTSMASP 350
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTS-----KPAHLNANDWATNGVGR 418
AG+ A + + R + + Q + P N NG G+
Sbjct 351 HVAGMGAYMIGMGAD--PRQVCDRLKQLATAAIRNPGSSTTNRLLYNGSGQ 399
>sp|Q5VJ74|SUB4_TRIVC Subtilisin-like protease 4 OS=Trichophyton
verrucosum OX=63417 GN=SUB4 PE=3 SV=1
Length=399
Score = 139 bits (351), Expect = 2e-34, Method: Composition-based stats.
Identities = 66/351 (19%), Positives = 121/351 (34%), Gaps = 44/351 (13%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R H R + + + +V ++EQ R + + W L V+ R
Sbjct 86 RGYHGHFDRDTLEEILNDSKVDYVEQDQVVRISGLVTQRSAPS------WGLGRVSHRQA 139
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
+ G G+ + +D GI+ NH D G G + D + +
Sbjct 140 GSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGRARWGTNTADRDN----------ADRH 189
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSA 252
HGT A A A G+A NA I V++L + + + G+N +
Sbjct 190 GHGTHTASTFAGTA------YGIAKNANIVAVKVLGSDGSGSTSGIIAGINYCVQD--AQ 241
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
G +A V++ G A+GN R+ + + ++
Sbjct 242 QRGILGKAAMNLSLGGGFSQANNDAVTR-AQNAGIFVAVAAGNDNRDARNYSP---ASAP 297
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
+++S+T + +S + Y+ G+ I+ T + +GTS ++P
Sbjct 298 AVCTVASSTINDSKSSFSNWGP--VVDIYAPGS----DIIAARPGGGST-TMSGTSMASP 350
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTS-----KPAHLNANDWATNGVGR 418
AG+ A + + R + + Q + P N NG G+
Sbjct 351 HVAGMGAYMIGMGAD--PRQVCDRLKQLATAAIRNPGSSTTNRLLYNGSGQ 399
>sp|Q64K33|SUB4_ARTBE Subtilisin-like protease 4 OS=Arthroderma
benhamiae OX=63400 GN=SUB4 PE=3 SV=1
Length=399
Score = 139 bits (351), Expect = 2e-34, Method: Composition-based stats.
Identities = 66/351 (19%), Positives = 121/351 (34%), Gaps = 44/351 (13%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R H R + + + +V ++EQ R + + W L V+ R
Sbjct 86 RGYHGHFDRDTLEEILNDSKVDYVEQDQVVRISGLVTQRSAPS------WGLGRVSHRQA 139
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
+ G G+ + +D GI+ NH D G G + D + +
Sbjct 140 GSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGRARWGTNTADRDN----------ADRH 189
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSA 252
HGT A A A G+A NA I V++L + + + G+N +
Sbjct 190 GHGTHTASTFAGTA------YGIAKNANIVAVKVLGSDGSGSTSGIIAGINYCVQD--AQ 241
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
G +A V++ G A+GN R+ + + ++
Sbjct 242 QRGILGKAAMNLSLGGGFSQANNDAVTR-AQNAGIFVAVAAGNDNRDARNYSP---ASAP 297
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
+++S+T + +S + Y+ G+ I+ T + +GTS ++P
Sbjct 298 AVCTVASSTINDSKSSFSNWGP--VVDIYAPGS----DIIAARPGGGST-TMSGTSMASP 350
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTS-----KPAHLNANDWATNGVGR 418
AG+ A + + R + + Q + P N NG G+
Sbjct 351 HVAGMGAYMIGMGAD--PRQVCDRLKQLATAAIRNPGSSTTNRLLYNGSGQ 399
>sp|D4AXW3|SUB4_ARTBC Subtilisin-like protease 4 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB4
PE=1 SV=2
Length=399
Score = 139 bits (351), Expect = 2e-34, Method: Composition-based stats.
Identities = 66/351 (19%), Positives = 121/351 (34%), Gaps = 44/351 (13%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R H R + + + +V ++EQ R + + W L V+ R
Sbjct 86 RGYHGHFDRDTLEEILNDSKVDYVEQDQVVRISGLVTQRSAPS------WGLGRVSHRQA 139
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
+ G G+ + +D GI+ NH D G G + D + +
Sbjct 140 GSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGRARWGTNTADRDN----------ADRH 189
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSA 252
HGT A A A G+A NA I V++L + + + G+N +
Sbjct 190 GHGTHTASTFAGTA------YGIAKNANIVAVKVLGSDGSGSTSGIIAGINYCVQD--AQ 241
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
G +A V++ G A+GN R+ + + ++
Sbjct 242 QRGILGKAAMNLSLGGGFSQANNDAVTR-AQNAGIFVAVAAGNDNRDARNYSP---ASAP 297
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
+++S+T + +S + Y+ G+ I+ T + +GTS ++P
Sbjct 298 AVCTVASSTINDSKSSFSNWGP--VVDIYAPGS----DIIAARPGGGST-TMSGTSMASP 350
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTS-----KPAHLNANDWATNGVGR 418
AG+ A + + R + + Q + P N NG G+
Sbjct 351 HVAGMGAYMIGMGAD--PRQVCDRLKQLATAAIRNPGSSTTNRLLYNGSGQ 399
>sp|Q69F35|SUB4_TRIRU Subtilisin-like protease 4 OS=Trichophyton
rubrum OX=5551 GN=SUB4 PE=1 SV=1
Length=399
Score = 139 bits (350), Expect = 2e-34, Method: Composition-based stats.
Identities = 66/351 (19%), Positives = 121/351 (34%), Gaps = 44/351 (13%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R H R + + + +V ++EQ R + + W L V+ R
Sbjct 86 RGYHGHFDRDTLEEILNDSKVDYVEQDQVVRISGLVTQRSAPS------WGLGRVSHRQA 139
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
+ G G+ + +D GI+ NH D G G + D + +
Sbjct 140 GSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGRARWGTNTADRDN----------ADRH 189
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSA 252
HGT A A A G+A NA I V++L + + + G+N +
Sbjct 190 GHGTHTASTFAGTA------YGIAKNANIVAVKVLGSDGSGSTSGIIAGINYCVQD--AQ 241
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
G +A V++ G A+GN ++ + + ++
Sbjct 242 QRGILGKAAMNLSLGGGFSQANNDAVTR-AQNAGIFVAVAAGNDNKDARNYSP---ASAP 297
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
+++S+T + +S + Y+ G+ I+ T + +GTS ++P
Sbjct 298 AVCTVASSTINDSKSSFSNWGP--VVDIYAPGS----DIIAARPGGGST-TMSGTSMASP 350
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTS-----KPAHLNANDWATNGVGR 418
AG+ A + N R + + Q + P N NG G+
Sbjct 351 HVAGMGAYMIGMGAN--PRQVCDRLKQLATAAIRNPGFSTTNRLLYNGSGQ 399
>sp|C5PGK9|SUB7A_COCP7 Subtilisin-like protease CPC735_050320
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_050320
PE=3 SV=1
Length=398
Score = 139 bits (350), Expect = 2e-34, Method: Composition-based stats.
Identities = 64/346 (18%), Positives = 112/346 (32%), Gaps = 63/346 (18%)
Query 46 NSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHS--RLQREPQVQWLEQQVAKR 103
+AR G N+G H ++ + + + V ++E+ +
Sbjct 61 ERLAR-RGSTNVG----GMRHTYNFNQGFMGYAGTFDEETIQEIANRDDVAYIERDQIMK 115
Query 104 RTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDL 163
+ + + P W L+ V+ R + G G+ I+D GI+ H D
Sbjct 116 ASA--IQTQRNVPS----WGLARVSSRQPGGRDYSYDSTAGQGVTAYIIDTGIDIRHTDF 169
Query 164 AGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGG 223
G G + + N HGT AG + GVA AR+
Sbjct 170 GGRAVWGTNTVDRRN----------EDCNGHGTHVAGTTGGTS------FGVAKRARLVA 213
Query 224 VRMLDGEVTDAVEARSLG--LNPNHI-------HIYSASWGPEDDGKTVDGPARLAEEAF 274
V++LD + + A G H + + S G + A +
Sbjct 214 VKVLDCNGSGSNSAVIAGMQWAMQHASQNDPRRAVANMSLGGGYSQASNQAAAAIVR--- 270
Query 275 FRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQ-FGNVPWYSEAC 333
G A+GN R+ S + S T+ ++A+ +S
Sbjct 271 ----------AGIFLAVAAGNDNRDARSFSPA----SEPTVCTAAASHVRDGKASFSNWG 316
Query 334 SSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIA 379
L Y+ G Q + + + S +GTS ++P G+ A
Sbjct 317 --QLVDVYAPG-----QDIISARPGGGSRSLSGTSMASPHVCGLGA 355
>sp|D4D674|SUB9_TRIVH Subtilisin-like protease 9 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB9 PE=3 SV=1
Length=397
Score = 139 bits (350), Expect = 2e-34, Method: Composition-based stats.
Identities = 73/405 (18%), Positives = 134/405 (33%), Gaps = 51/405 (13%)
Query 17 LVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRS 76
+V+ + ++ + WA +I + G L F G+ S
Sbjct 39 VVMKSTISEAEFQTHQAWASKIHRRN-LGERDETLGGLDGLKTTFE------FEGLKGYS 91
Query 77 LSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKA 136
+ + + R P V ++E + + + P W L ++ +
Sbjct 92 GAFDKRTIELISRNPAVDYVEVDRVVKLDA--ITTQRNAPS----WGLGRISHKSAGSSD 145
Query 137 AWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGT 196
G GI + +D GI+ HP+ G G + N+ + N HGT
Sbjct 146 FVFDDSAGSGITIYGVDTGIDIKHPEFGGRATWGTNTVDNE----------DTDQNGHGT 195
Query 197 RCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGP 256
AG A G+A A + V++L+ + T + G+ H
Sbjct 196 HTAGTFAGAT------YGIAKKANVIAVKVLNAQGTGSTSGVIQGIQWCTDHAGRNGLKG 249
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
+ ++ + F V++ G A+GN G S G + T S
Sbjct 250 K---AAMNLSLGIRGSTVFNRVAEAAQQSGIFLAVAAGNDGFSPAS--ARGVCTAAATNS 304
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAG 376
+AT + N ++ Y G I++ + T + +GTS ++P G
Sbjct 305 QDAATSWSNY--------GSVVAVYGPGA----DIISAYPNED-TATLSGTSMASPHVCG 351
Query 377 IIALTLE---ANKNLTWRDMQHLVVQTSKPAHLN-ANDWATNGVG 417
+ A + + ++ L V++ LN NG G
Sbjct 352 VGAYLMALEGIGPDKVCDRIKELAVESVTNQKLNTTRKLLYNGSG 396
>sp|A7UKV6|SUB4_TRIEQ Subtilisin-like protease 4 (Fragment) OS=Trichophyton
equinum OX=63418 GN=SUB4 PE=3 SV=1
Length=394
Score = 139 bits (349), Expect = 3e-34, Method: Composition-based stats.
Identities = 66/343 (19%), Positives = 120/343 (35%), Gaps = 39/343 (11%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R H R + + + +V ++EQ R + + W L V+ R
Sbjct 84 RGYHGHFDRDTLEEILNDSKVDYVEQDQVVRISGLVTQRGAPS------WGLGRVSHRQA 137
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
+ G G+ + +D GI+ NH D G G + D + +
Sbjct 138 GSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGRARWGTNTADRDN----------ADRH 187
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSA 252
HGT A A A G+A NA I V++L + + + G+N +
Sbjct 188 GHGTHTASTFAGTA------YGIAKNANIVAVKVLSSDGSGSTSGIIAGINYCVQD--AQ 239
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
G +A V++ G A+GN R+ + + ++
Sbjct 240 QRGILGKAAMNLSLGGGFSQANNDAVTR-AQNAGIFVAVAAGNDNRDARNYSP---ASAP 295
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
+++S+T + +S + Y+ G+ I+ T + +GTS ++P
Sbjct 296 AVCTVASSTINDSKSSFSNWGP--VVDIYAPGS----DIIAARPGGGST-TMSGTSMASP 348
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNG 415
AG+ A + + R + + Q + PA N TN
Sbjct 349 HVAGMGAYMIGLGAD--PRSLCDRLKQLATPAIRNPGSSTTNR 389
>sp|B8XGQ7|SUB4_TRITO Subtilisin-like protease 4 OS=Trichophyton
tonsurans OX=34387 GN=SUB4 PE=3 SV=1
Length=399
Score = 139 bits (349), Expect = 3e-34, Method: Composition-based stats.
Identities = 66/343 (19%), Positives = 120/343 (35%), Gaps = 39/343 (11%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R H R + + + +V ++EQ R + + W L V+ R
Sbjct 86 RGYHGHFDRDTLEEILNDSKVDYVEQDQVVRISGLVTQRGAPS------WGLGRVSHRQA 139
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
+ G G+ + +D GI+ NH D G G + D + +
Sbjct 140 GSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGRARWGTNTADRDN----------ADRH 189
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSA 252
HGT A A A G+A NA I V++L + + + G+N +
Sbjct 190 GHGTHTASTFAGTA------YGIAKNANIVAVKVLGSDGSGSTSGIIAGINYCVQD--AQ 241
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
G +A V++ G A+GN R+ + + ++
Sbjct 242 QRGILGKAAMNLSLGGGFSQANNDAVTR-AQNAGIFVAVAAGNDNRDARNYSP---ASAP 297
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
+++S+T + +S + Y+ G+ I+ T + +GTS ++P
Sbjct 298 AVCTVASSTINDSKSSFSNWGP--VVDIYAPGS----DIIAARPGGGST-TMSGTSMASP 350
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNG 415
AG+ A + + R + + Q + PA N TN
Sbjct 351 HVAGMGAYMIGLGAD--PRSLCDRLKQLATPAIRNPGSSTTNR 391
>sp|C5FXZ6|SUB4_ARTOC Subtilisin-like protease 4 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB4
PE=3 SV=1
Length=399
Score = 138 bits (348), Expect = 4e-34, Method: Composition-based stats.
Identities = 65/351 (19%), Positives = 121/351 (34%), Gaps = 44/351 (13%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R H + + + +V ++E R + + W L V+ R
Sbjct 86 RGYHGHFDPDTLDEILNDSKVDYVEHDQIVRISGLVTQRSAPS------WGLGRVSHRQA 139
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
++ G G+ + +D GI+ NH D G G + D + +
Sbjct 140 GIRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGRARWGTNTADRDN----------ADRH 189
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSA 252
HGT A A G+A NA I V++L + + + G+N +
Sbjct 190 GHGTHTASTFAGTT------YGIAKNANIVAVKVLGSDGSGSTSGIIAGINFCVQD--AQ 241
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
S G +A V++ G A+GN ++ + + ++
Sbjct 242 SRGILGKAAMNLSLGGGFSQANNDAVTR-AQNAGIFVAVAAGNDNKDARNYSP---ASAP 297
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
+++S+T + +S S + Y+ G+ I+ T + +GTS ++P
Sbjct 298 AVCTVASSTVNDSKSSFSNYGS--IVDIYAPGS----DIIAARPGGGST-TMSGTSMASP 350
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTS-----KPAHLNANDWATNGVGR 418
AG+ A + + R + + Q S P N NG G+
Sbjct 351 HVAGMGAYMIGMG--IDPRQVCDRLKQISLPAIRSPGPSTTNRLLYNGSGQ 399
>sp|P28842|SUBT_BACS9 Subtilisin OS=Bacillus sp. (strain TA39)
OX=29336 GN=sub1 PE=1 SV=1
Length=420
Score = 139 bits (349), Expect = 4e-34, Method: Composition-based stats.
Identities = 58/343 (17%), Positives = 115/343 (34%), Gaps = 25/343 (7%)
Query 97 EQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGI 156
E ++A K + W + + ++ Q G GI +++LD G+
Sbjct 94 ELEIATATDKPEALYNAMAASQSTPWGIKAIYNN-----SSITQTSGGGGINIAVLDTGV 148
Query 157 EKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVA 216
NHPDL N + F V + + HGT AG A G GVA
Sbjct 149 NTNHPDLRNNVEQCKDFTV----GTTYTNNSCTDRQGHGTHVAGSALADGGTGNGVYGVA 204
Query 217 YNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFR 276
+A + ++L + + + + + H + + + + +
Sbjct 205 PDADLWAYKVLGDDGSGYADDIAAAIR--HAGDQATALNTKV-VINMSLGSSGESSLITN 261
Query 277 GVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFG---NVPWYSEAC 333
V+ G + + A+GN G S G + ++ V +S
Sbjct 262 AVNYS-YNKGVLIIAAAGNSGPYQGSIGYPGALVNAVAVAALENKVENGTYRVADFSSRG 320
Query 334 SSTLATTYS------SGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKN 387
S Y+ + I +T + +GTS ++P AAG+ A +
Sbjct 321 YSWTDGDYAIQKGDVEISAPGAAIYSTWFDGG-YATISGTSMASPHAAGLAAKIWAQYPS 379
Query 388 LTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLD 430
+ D++ + + + + + G G + +G+ +
Sbjct 380 ASNVDVRGELQYRAYENDILSGYY--AGYGDDFASGFGFATVQ 420
>sp|C5P5Q3|SUB9_COCP7 Subtilisin-like protease CPC735_033790 OS=Coccidioides
posadasii (strain C735) OX=222929 GN=CPC735_033790
PE=3 SV=1
Length=399
Score = 138 bits (347), Expect = 5e-34, Method: Composition-based stats.
Identities = 61/318 (19%), Positives = 115/318 (36%), Gaps = 41/318 (13%)
Query 70 RGVTKRSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGV 127
+ S R + ++ V ++E T + P + L +
Sbjct 80 SATGMKGYSGSFARETIEQIANNSAVAYVEPDRMVNITA--FVTQRNAPSY----GLGRI 133
Query 128 TQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYT 187
+ + + G GI + +D GI+ HP+ G G + ++ND
Sbjct 134 SNKRPGNRDYIFDESAGRGITIYGVDTGIDIRHPEFEGRATWGTN-EIND---------V 183
Query 188 QMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN--PN 245
++N HGT AG A GVA A I V++L+ E + + G+N +
Sbjct 184 NQDENGHGTHTAGTFAGRN------FGVAKRANIVAVKVLNAEGSGSTSGIISGINWCVD 237
Query 246 HIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNC 305
H + G ++ G AF + + G A+GN G + + +
Sbjct 238 HAR-RNNILGRAVMNLSLGGTGA---RAFNQVATNAAN-AGIFLAVAAGNDGEDAANTSP 292
Query 306 DGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHT 365
++ ++S++T+ +S S + Y+ G+Q + + +
Sbjct 293 ---ASARGVCTVSASTERDTRADFSNFGS--VVDIYAPGDQ-----IPSVFPNNARRVLS 342
Query 366 GTSASAPLAAGIIALTLE 383
GTS +AP AG+ A +
Sbjct 343 GTSMAAPHVAGVGAYLMA 360
>sp|P29141|SUBV_BACSU Minor extracellular protease Vpr OS=Bacillus
subtilis (strain 168) OX=224308 GN=vpr PE=1 SV=1
Length=806
Score = 143 bits (360), Expect = 6e-34, Method: Composition-based stats.
Identities = 56/195 (29%), Positives = 83/195 (43%), Gaps = 22/195 (11%)
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND 191
+ AW GYTG GI V+I+D G+E NHPDL N+ +D D D DP+ T
Sbjct 168 IGANDAWDLGYTGKGIKVAIIDTGVEYNHPDLKKNFGQYKGYDFVDNDYDPKETPTGDPR 227
Query 192 NR---HGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN---PN 245
HGT AG VAA NG GVA +A + R+L + E G+ +
Sbjct 228 GEATDHGTHVAGTVAA---NGT-IKGVAPDATLLAYRVLGPGGSGTTENVIAGVERAVQD 283
Query 246 HIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNC 305
+ + S G +++ P A +S+ G + V ++GN G +
Sbjct 284 GADVMNLSLG-----NSLNNPDWATSTALDWAMSE-----GVVAVTSNGNSGPNGWTVGS 333
Query 306 DGYTNSIYTLSISSA 320
G S +S+ +
Sbjct 334 PG--TSREAISVGAT 346
Score = 48.3 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 22/118 (19%), Positives = 43/118 (36%), Gaps = 6/118 (5%)
Query 306 DGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTT----DLRQKC- 360
G T + + L++S A + S + IV+T D
Sbjct 467 AGETKTTFKLTVSKALGEQVADFSSRGPVMDTWMIKPDISAPGVNIVSTIPTHDPDHPYG 526
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAND-WATNGVG 417
S GTS ++P AG +A+ +A + ++ ++ T+ + + + N G
Sbjct 527 YGSKQGTSMASPHIAGAVAVIKQAKPKWSVEQIKAAIMNTAVTLKDSDGEVYPHNAQG 584
>sp|P20015|PRTT_PARAQ Proteinase T (Fragment) OS=Parengyodontium
album OX=37998 GN=PROT PE=1 SV=1
Length=293
Score = 135 bits (339), Expect = 7e-34, Method: Composition-based stats.
Identities = 52/299 (17%), Positives = 91/299 (30%), Gaps = 57/299 (19%)
Query 94 QWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILD 153
+++EQ + + W L+ ++ ++ G G I+D
Sbjct 1 EFIEQDAVVTISA---------TQEDAPWGLARISSQEPGGTTYTYDDSAGTGTCAYIID 51
Query 154 DGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGV 213
GI NH D G +F + QD D N HGT AG V
Sbjct 52 TGIYTNHTDFGGRAKFLKNFAGDGQDTD---------GNGHGTHVAGTVGGTT------Y 96
Query 214 GVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIH----------IYSASWGPEDDGKTV 263
GVA + V++LD + G++ + + S G
Sbjct 97 GVAKKTSLFAVKVLDANGQGSNSGVIAGMDFVTKDASSQNCPKGVVVNMSLGGPSSSAVN 156
Query 264 DGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQF 323
A + G A+GN + S + + ++ + +
Sbjct 157 RAAAEIT-------------SAGLFLAVAAGNEATDASSSSP---ASEESACTVGATDKT 200
Query 324 GNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTL 382
+ YS S + + + T+ +GTS ++P AG+ A L
Sbjct 201 DTLAEYSNFGSVVDLLAPGTD-------IKSTWNDGRTKIISGTSMASPHVAGLGAYFL 252
>sp|Q8SQJ3|SPL1_ENCCU Putative subtilisin-like proteinase 1 OS=Encephalitozoon
cuniculi (strain GB-M1) OX=284813 GN=SPL1 PE=2
SV=1
Length=465
Score = 139 bits (349), Expect = 9e-34, Method: Composition-based stats.
Identities = 67/388 (17%), Positives = 123/388 (32%), Gaps = 81/388 (21%)
Query 78 SPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFP------QQWYLSGVTQRD 131
R++R P V+ + + + +D + W L+ V
Sbjct 66 RMSESTAERMKRHPSVKMVVKDSPVGISGLKFDVPGSDDRSGIVMQRHAPWGLARVGGSV 125
Query 132 LNVKAAWAQGY-TGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMN 190
V + +G G+ V +LD G+E HP+ G GA+F P+ +
Sbjct 126 SLVHGNYCYPINSGKGVDVYVLDTGVEIEHPEFGGRARWGANFV---------PKSPDRD 176
Query 191 DNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN------- 243
++ HGT CAG + G GV + I V++LD + G++
Sbjct 177 EHGHGTHCAGVI------GGKNFGVTKESSIIAVKVLDKYGSGMTSRLLQGVDFVIKEHE 230
Query 244 -------PNHIHIYSASWGPEDDGKTVDGPARL--------------------------- 269
Y +S G D +DG
Sbjct 231 KKKDELYNAAADEYLSSGGSSDIEIEMDGSESFSFVQPETPSIQRLVDAISRKALQPKTV 290
Query 270 -------AEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQ 322
A + LG F A+GN D+C+ +S ++ ++T
Sbjct 291 VNLSVGGFRNAALNFAIEYASRLGIHFSTAAGNE--HEDACDFSP-GSSRAAITTGASTY 347
Query 323 FGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTL 382
V ++S ++ G + + + +GTS +AP +G IA L
Sbjct 348 RDTVAFFSNFGK--CVNVFAPGVD-----ILSSWIGGTQKIVSGTSMAAPHTSGAIAAYL 400
Query 383 EANKNLTWRDMQHLVVQTSKPAHLNAND 410
+ ++ ++ ++ + D
Sbjct 401 TYY-DYDPHMLKSRIIGDARLIEDVSED 427
>sp|P29118|ALP_HAPCH Alkaline proteinase OS=Hapsidospora chrysogena
OX=5044 GN=ALP PE=3 SV=1
Length=402
Score = 137 bits (344), Expect = 1e-33, Method: Composition-based stats.
Identities = 59/308 (19%), Positives = 107/308 (35%), Gaps = 34/308 (11%)
Query 86 RLQREPQVQWLEQ-QVAKRRTKRDVYQEPTDPKFPQQ--WYLSGVTQRDLNVKAAWAQGY 142
++ P V +E+ Q+ ++D + T Q W L ++ R +
Sbjct 90 EIKNNPDVLEVEEDQIWHLFDEQDEGEFSTAALVTQNGAWGLGTISHRQPGSTSYIYDDS 149
Query 143 TGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEV 202
G G ++D GI ++H + +G G + + N HGT AG +
Sbjct 150 AGSGTYAYVVDTGILESHNEFSGRAITGYNAVGGSN----------ADTNGHGTHVAGTI 199
Query 203 AAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKT 262
GVA N + V++ G + + G N I + G ++
Sbjct 200 GGRT------YGVAKNTNLIAVKVFRGSSS-STSIILDGFNWAVNDIINR--GRQNKAAI 250
Query 263 VDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQ 322
AF V G + V A+GN + + + N+I ++ S
Sbjct 251 SMSLGGGYSSAFNNAV-NTAYSRGVLSVVAAGNDNQNAANYSPASAANAI---TVGSIAS 306
Query 323 FGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC-TESHTGTSASAPLAAGIIALT 381
+S S + I++ + T + +GTS + P G++ L
Sbjct 307 NWARSSFSNYGSVLDIFAPGT------SILSAWIGGNSATNTISGTSMATPHVTGVV-LY 359
Query 382 LEANKNLT 389
L+A + LT
Sbjct 360 LQALEGLT 367
>sp|C5P9H3|SUB7D_COCP7 Subtilisin-like protease CPC735_005570
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_005570
PE=3 SV=1
Length=394
Score = 137 bits (344), Expect = 1e-33, Method: Composition-based stats.
Identities = 63/308 (20%), Positives = 114/308 (37%), Gaps = 57/308 (19%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
++ +P V+++E Q+ W L+ ++ + + G
Sbjct 95 QIANDPAVKYIEHDRIANARGLVEQQDAG-------WNLARISHKKTGARTYVYDKSAGA 147
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
GI V ++D G++ ++PDL G GA+F ND + N HGT A +A
Sbjct 148 GISVCLVDTGVDVDNPDLGGRATWGANFVDND----------DSDGNGHGTFLASLIAGQ 197
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDA----VEARSLGLNPNHIH------IYSASWG 255
GVA A+I V++LD + + + + H + + S G
Sbjct 198 K------HGVAKKAKIIAVKVLDANGSGSYSNVISGIDWCVKYAKEHGISERMVVNLSLG 251
Query 256 PEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTL 315
G ++ +A V G ++ GG D+ N D ++
Sbjct 252 --------GGYSQAVNQAAENAVLAG-------MFVSAAVGGSNRDARN-DSPASARGVC 295
Query 316 SISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAA 375
+I+++T +S S + Y+ G + I+ T +GTS +A A+
Sbjct 296 AIAASTMDDKAALFSNYGS--IVAVYAPG----QNIMAAGRMGSVT--LSGTSFAAGHAS 347
Query 376 GIIALTLE 383
G+ A L
Sbjct 348 GVGAYLLA 355
>sp|Q5VJ77|SUB1_TRIVC Subtilisin-like protease 1 (Fragment) OS=Trichophyton
verrucosum OX=63417 GN=SUB1 PE=3 SV=1
Length=399
Score = 135 bits (340), Expect = 5e-33, Method: Composition-based stats.
Identities = 51/297 (17%), Positives = 106/297 (36%), Gaps = 34/297 (11%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ ++P+V ++E + ++ P W L+ ++ + G G
Sbjct 98 IAKDPKVMFVEPDTI--ISVHGKVEQSNVPS----WGLARISNPQPGAGSYIYDSSAGEG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I V +D G++ NH D G G S VND D + + HGT +G +
Sbjct 152 ITVYSVDTGVDVNHEDFEGRAIWG-SNQVNDGD--------DRDGSGHGTHTSGTMVGKE 202
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
G+A A++ V++L + + G+N + H + ++
Sbjct 203 ------FGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWSVEHARQNGGTKK---AVMNMS 253
Query 267 ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNV 326
+ + + G A+GN ++ S + + ++ S+ + +
Sbjct 254 LGGSSSSALNRAAAQAVEQGMFLSVAAGNDNQDAQSSSP---ASEPSVCTVGSSAEDDSR 310
Query 327 PWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE 383
+S + S + + ++S +GTS +AP AG+ A +
Sbjct 311 SSFSNWGPAIDLFAPGS-------NIISARPGGGSQSMSGTSMAAPHVAGLAAYLMA 360
>sp|Q64K30|SUB1_ARTBE Subtilisin-like protease 1 (Fragment) OS=Arthroderma
benhamiae OX=63400 GN=SUB1 PE=3 SV=1
Length=399
Score = 135 bits (340), Expect = 5e-33, Method: Composition-based stats.
Identities = 51/297 (17%), Positives = 106/297 (36%), Gaps = 34/297 (11%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ ++P+V ++E + ++ P W L+ ++ + G G
Sbjct 98 IAKDPKVMFVEPDTI--ISVHGKVEQSNVPS----WGLARISNPQPGAGSYIYDSSAGEG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I V +D G++ NH D G G S VND D + + HGT +G +
Sbjct 152 ITVYSVDTGVDVNHEDFEGRAIWG-SNQVNDGD--------DRDGSGHGTHTSGTMVGKE 202
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
G+A A++ V++L + + G+N + H + ++
Sbjct 203 ------FGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWSVEHARQNGGTKK---AVMNMS 253
Query 267 ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNV 326
+ + + G A+GN ++ S + + ++ S+ + +
Sbjct 254 LGGSSSSALNRAAAQAVEQGMFLSVAAGNDNQDAQSSSP---ASEPSVCTVGSSAEDDSR 310
Query 327 PWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE 383
+S + S + + ++S +GTS +AP AG+ A +
Sbjct 311 SSFSNWGPAIDLFAPGS-------NIISARPGGGSQSMSGTSMAAPHVAGLAAYLMA 360
>sp|E4UPZ4|SUB1_ARTGP Subtilisin-like protease 1 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB1
PE=3 SV=1
Length=481
Score = 136 bits (343), Expect = 7e-33, Method: Composition-based stats.
Identities = 56/308 (18%), Positives = 107/308 (35%), Gaps = 56/308 (18%)
Query 87 LQREPQVQWLEQQ-VAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
+ ++P+V ++E + K D P+ W L+ ++ + G
Sbjct 98 IAKDPKVMFVEPDTIISVHGKVDQNNVPS-------WGLARISSSKPGTQDYTYDSSAGE 150
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
GI V +D G++ NH D G G++ + D D HGT +G +
Sbjct 151 GITVYSVDTGVDINHEDFEGRAIWGSNQVNDGDDNDRS---------GHGTHTSGTMVGK 201
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIH----------IYSASWG 255
G+A A++ V++L + + G+N H + + S G
Sbjct 202 E------FGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWCVEHARQNGGTNKAVMNMSLG 255
Query 256 PEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTL 315
G + A + V Q G A+GN + S + +
Sbjct 256 --------GGSSSALNRAAAQAVEQ-----GMFLSVAAGNDNTDARSSSP---ASEPSVC 299
Query 316 SISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAA 375
++ ++ + + +S S S + + ++S +GTS +AP A
Sbjct 300 TVGASAEDDSRSSFSNWGPSLDLFAPGS-------NIISARPGGGSQSMSGTSMAAPHVA 352
Query 376 GIIALTLE 383
G+ A +
Sbjct 353 GLAAYLMA 360
>sp|Q69F58|SUB1_TRIRU Subtilisin-like protease 1 OS=Trichophyton
rubrum OX=5551 GN=SUB1 PE=2 SV=1
Length=504
Score = 136 bits (343), Expect = 9e-33, Method: Composition-based stats.
Identities = 57/300 (19%), Positives = 109/300 (36%), Gaps = 40/300 (13%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ ++P+V ++E + ++ P W L+ ++ + G G
Sbjct 98 IAKDPKVMFVEPDTIV--SVHGKVEQSNVPS----WGLARISNPQPGADSYTYDSSAGEG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I V +D G++ NH D G G S VND D + + HGT +G +
Sbjct 152 ITVYSVDTGVDVNHEDFEGRAIWG-SNQVNDGD--------DRDGSGHGTHTSGTMVG-- 200
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTV--- 263
G+A A++ V++L + + G+N + H + G + +
Sbjct 201 ----KMYGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWSVEH-ARQNGGTKKAVMNMSLG 255
Query 264 DGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQF 323
+ A + V Q G A+GN ++ S + + ++ S+ +
Sbjct 256 GSSSSALNRAAAQAVEQ-----GMFLSVAAGNDNQDAQSSSP---ASEPSVCTVGSSAED 307
Query 324 GNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE 383
+ +S + S IV+ +S +GTS +AP AG+ A +
Sbjct 308 DSRSSFSNWGPAIDIFAPGS------NIVSARPGGGS-QSMSGTSMAAPHVAGLAAYLMA 360
>sp|E4UWA4|SUB4_ARTGP Subtilisin-like protease 4 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB4
PE=3 SV=1
Length=399
Score = 133 bits (335), Expect = 2e-32, Method: Composition-based stats.
Identities = 66/343 (19%), Positives = 120/343 (35%), Gaps = 39/343 (11%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
R H R + + + +V ++EQ R + + W L V+ R
Sbjct 86 RGYHGHFDRDTLEEILNDSKVSYVEQDQVVRISGLTTQRSAPS------WGLGRVSHRRA 139
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
+ G G+ + +D GI+ H D G G + D + +
Sbjct 140 GSRDYVFDDSAGRGVTIYGVDTGIDIRHQDFGGRARWGTNTADRDN----------ADRH 189
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSA 252
HGT A A A G+A NA I V++L + + + G+N +
Sbjct 190 GHGTHTASTFAGTA------FGIAKNANIVAVKVLGSDGSGSTSGIIAGINYCVQD--AQ 241
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
G +A V++ G A+GN R+ + + ++
Sbjct 242 QRGILGKAAMNLSLGGGFSQANNDAVTR-AQNAGIFVAVAAGNDNRDARAYSP---ASAP 297
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
+++S+T + +S S + Y+ G+ + ++S +GTS ++P
Sbjct 298 AVCTVASSTIQDSKSSFSNWGS--IVDIYAPGSD-----IIAARPGGGSQSMSGTSMASP 350
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNG 415
AG+ A + + R + + Q S PA N TN
Sbjct 351 HVAGMGAYLIGMGAD--PRRVCDQLKQLSTPAISNPGSGTTNR 391
>sp|P09489|PRTS_SERMA Extracellular serine protease OS=Serratia
marcescens OX=615 PE=1 SV=1
Length=1045
Score = 137 bits (345), Expect = 5e-32, Method: Composition-based stats.
Identities = 73/401 (18%), Positives = 138/401 (34%), Gaps = 80/401 (20%)
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVN 176
+F +QW L ++ + A+A+GYTG GI + ++D+ I +H + +G + N
Sbjct 45 EFNRQWGLEAIS-----AEFAYARGYTGKGITIGVIDNAI-LSHSEFSGKL----TRLDN 94
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAV 235
+ M+ HGT AG +AA +G GVA++A I G ++ D G
Sbjct 95 GSYNFSYDKQDNMSFGDHGTHVAG-IAAAKRDGAGMHGVAFDADIIGTKLNDYGNRNGRE 153
Query 236 EAR---------SLGLNPN-----HIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQG 281
E S G+ P+ I G D V V G
Sbjct 154 ELIQSAARVINNSWGIAPDIRRDAKGDIIWLPNGRPDYVAFVKSEVIAEMMRSKSSVEWG 213
Query 282 ------------------RGGLGSIFVWASGNGGREH--DSCNCDGYT------------ 309
G + V+++GN + ++ Y
Sbjct 214 SEQPVPTGGHSAMSTLLRAARHGKLIVFSAGNYNNYNIPEAQKSLPYAFPDVLNNYLIVT 273
Query 310 --NSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQK-------C 360
+ LS+SS + + A S + +T N V + K
Sbjct 274 NLSDENQLSVSSTSCGQTASYCVSAPGSDIYSTVGRLESNTGGAVNREAYNKGELSLNPG 333
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
+ +GTS +AP G+ A+ ++ ++ + ++ T+ + +
Sbjct 334 YGNKSGTSMAAPHVTGVAAVLMQRFPYMSADQISAVIKTTATDLGVAG-----------I 382
Query 421 SHSYGYGLLDAGAMVALAQNWTTVA--PQRKCIIDILTEPK 459
+ +G+G ++ + + + T PQ + +E +
Sbjct 383 DNLFGWGRVNLRDAINGPKMFITKEDIPQEYYVPGSYSEKQ 423
>sp|D4AKU9|SUB1_ARTBC Subtilisin-like protease 1 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB1
PE=2 SV=2
Length=533
Score = 134 bits (337), Expect = 8e-32, Method: Composition-based stats.
Identities = 55/300 (18%), Positives = 109/300 (36%), Gaps = 40/300 (13%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ ++P+V ++E + ++ P W L+ ++ + G G
Sbjct 98 IAKDPKVMFVEPDTI--ISVHGKVEQSNVPS----WGLARISNPQPGAGSYIYDSSAGEG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I V +D G++ NH D G G S VND D + + HGT +G +
Sbjct 152 ITVYSVDTGVDVNHEDFEGRAIWG-SNQVNDGD--------DRDGSGHGTHTSGTMVGKE 202
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTV--- 263
G+A A++ V++L + + G+N + H + G + +
Sbjct 203 ------FGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWSVEH-ARQNGGTKKAVMNMSLG 255
Query 264 DGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQF 323
+ A + V Q G A+GN ++ S + + ++ S+ +
Sbjct 256 GSSSSALNRAAAQAVEQ-----GMFLSVAAGNDNQDAQSSSP---ASEPSVCTVGSSAED 307
Query 324 GNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE 383
+ +S + S + + ++S +GTS +AP AG+ A +
Sbjct 308 DSRSSFSNWGPAIDLFAPGS-------NIISARPGGGSQSMSGTSMAAPHVAGLAAYLMA 360
>sp|B6VA84|SUB1_TRIEQ Subtilisin-like protease 1 OS=Trichophyton
equinum OX=63418 GN=SUB1 PE=3 SV=1
Length=507
Score = 133 bits (335), Expect = 9e-32, Method: Composition-based stats.
Identities = 52/297 (18%), Positives = 106/297 (36%), Gaps = 34/297 (11%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ ++P+V ++E + ++ P W L+ ++ + G G
Sbjct 98 IAKDPKVMFVEPDTIISVNGK--VEQSNVPS----WGLARISNSQPGANSYVYDSSAGEG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I V +D G++ NH D G G S VND D + + HGT +G +
Sbjct 152 ITVYSVDTGVDINHEDFEGRAIWG-SNQVNDGD--------DRDGSGHGTHTSGTMVGKE 202
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
G+A A++ V++L + + G+N H +D ++
Sbjct 203 ------FGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWCVEHARQNGG---NDKAVMNMS 253
Query 267 ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNV 326
+ + + G A+GN ++ S + + ++ S+ + +
Sbjct 254 LGGSSSSALNRAAAQAVEQGMFLSVAAGNENQDARSSSP---ASEPSVCTVGSSAEDDSR 310
Query 327 PWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE 383
+S + S + + ++S +GTS +AP AG+ A +
Sbjct 311 SSFSNWGPALDLFAPGS-------NIISARPGGGSQSMSGTSMAAPHVAGLAAYLMA 360
>sp|D4DIW9|SUB1_TRIVH Subtilisin-like protease 1 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB1 PE=3 SV=1
Length=518
Score = 134 bits (336), Expect = 1e-31, Method: Composition-based stats.
Identities = 55/300 (18%), Positives = 109/300 (36%), Gaps = 40/300 (13%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ ++P+V ++E + ++ P W L+ ++ + G G
Sbjct 98 IAKDPKVMFVEPDTI--ISVHGKVEQSNVPS----WGLARISNPQPGAGSYIYDSSAGEG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I V +D G++ NH D G G S VND D + + HGT +G +
Sbjct 152 ITVYSVDTGVDVNHEDFEGRAIWG-SNQVNDGD--------DRDGSGHGTHTSGTMVGKE 202
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTV--- 263
G+A A++ V++L + + G+N + H + G + +
Sbjct 203 ------FGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWSVEH-ARQNGGTKKAVMNMSLG 255
Query 264 DGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQF 323
+ A + V Q G A+GN ++ S + + ++ S+ +
Sbjct 256 GSSSSALNRAAAQAVEQ-----GMFLSVAAGNDNQDAQSSSP---ASEPSVCTVGSSAED 307
Query 324 GNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE 383
+ +S + S + + ++S +GTS +AP AG+ A +
Sbjct 308 DSRSSFSNWGPAIDLFAPGS-------NIISARPGGGSQSMSGTSMAAPHVAGLAAYLMA 360
>sp|P12547|ORYZ_ASPOR Alkaline protease 1 OS=Aspergillus oryzae
(strain ATCC 42149 / RIB 40) OX=510516 GN=alp1 PE=1 SV=2
Length=403
Score = 131 bits (330), Expect = 1e-31, Method: Composition-based stats.
Identities = 54/315 (17%), Positives = 105/315 (33%), Gaps = 58/315 (18%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
+++ V ++E+ + Y + + W L ++ + G
Sbjct 102 EIRKNEDVAYVEED-------QIYYLDGLTTQKSAPWGLGSISHKGQQSTDYIYDTSAGE 154
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G ++D G+ +H + G AS N ++ HGT +G +A
Sbjct 155 GTYAYVVDSGVNVDHEEFEGR----ASKAYNAAGG------QHVDSIGHGTHVSGTIAGK 204
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHI----------YSASWG 255
G+A A I V++ GE + + G N I + S G
Sbjct 205 T------YGIAKKASILSVKVFQGESS-STSVILDGFNWAANDIVSKKRTSKAAINMSLG 257
Query 256 PEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTL 315
G ++ +A Q G + V A+GN + + ++I
Sbjct 258 --------GGYSKAFNDAVENAFEQ-----GVLSVVAAGNENSDAGQTSPASAPDAI--- 301
Query 316 SISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC-TESHTGTSASAPLA 374
++++ + N +S I++ + T + +GTS + P
Sbjct 302 TVAAIQKSNNRASFSNFGKVVDVFAPGQ------DILSAWIGSSSATNTISGTSMATPHI 355
Query 375 AGIIALTLEANKNLT 389
G ++L L A +NL
Sbjct 356 VG-LSLYLAALENLD 369
>sp|B8N106|ORYZ_ASPFN Alkaline protease 1 OS=Aspergillus flavus
(strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 /
JCM 12722 / SRRC 167) OX=332952 GN=alp1 PE=1 SV=1
Length=403
Score = 131 bits (330), Expect = 1e-31, Method: Composition-based stats.
Identities = 54/315 (17%), Positives = 105/315 (33%), Gaps = 58/315 (18%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
+++ V ++E+ + Y + + W L ++ + G
Sbjct 102 EIRKNEDVAYVEED-------QIYYLDGLTTQKSAPWGLGSISHKGQQSTDYIYDTSAGE 154
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G ++D G+ +H + G AS N ++ HGT +G +A
Sbjct 155 GTYAYVVDSGVNVDHEEFEGR----ASKAYNAAGG------QHVDSIGHGTHVSGTIAGK 204
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHI----------YSASWG 255
G+A A I V++ GE + + G N I + S G
Sbjct 205 T------YGIAKKASILSVKVFQGESS-STSVILDGFNWAANDIVSKKRTSKAAINMSLG 257
Query 256 PEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTL 315
G ++ +A Q G + V A+GN + + ++I
Sbjct 258 --------GGYSKAFNDAVENAFEQ-----GVLSVVAAGNENSDAGQTSPASAPDAI--- 301
Query 316 SISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC-TESHTGTSASAPLA 374
++++ + N +S I++ + T + +GTS + P
Sbjct 302 TVAAIQKSNNRASFSNFGKVVDVFAPGQ------DILSAWIGSSSATNTISGTSMATPHI 355
Query 375 AGIIALTLEANKNLT 389
G ++L L A +NL
Sbjct 356 VG-LSLYLAALENLD 369
>sp|B8XGQ4|SUB1_TRITO Subtilisin-like protease 1 OS=Trichophyton
tonsurans OX=34387 GN=SUB1 PE=3 SV=1
Length=507
Score = 133 bits (334), Expect = 1e-31, Method: Composition-based stats.
Identities = 52/297 (18%), Positives = 105/297 (35%), Gaps = 34/297 (11%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ ++P+V ++E + ++ P W L+ ++ + G G
Sbjct 98 IAKDPKVMFVEPDTIISVNGK--VEQSNVPS----WGLARISNSQPGANSYVYDSSAGEG 151
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I V +D G++ NH D G G S VND D + + HGT +G +
Sbjct 152 ITVYSVDTGVDINHEDFEGRAIWG-SNQVNDGD--------DRDGSGHGTHTSGTMVGKE 202
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGP 266
G+A A++ V++L + + G+N H D ++
Sbjct 203 ------FGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWCVEHARQNGG---TDKAVMNMS 253
Query 267 ARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNV 326
+ + + G A+GN ++ S + + ++ S+ + +
Sbjct 254 LGGSSSSALNRAAAQAVEQGMFLSVAAGNENQDARSSSP---ASEPSVCTVGSSAEDDSR 310
Query 327 PWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE 383
+S + S + + ++S +GTS +AP AG+ A +
Sbjct 311 SSFSNWGPALDLFAPGS-------NIISARPGGGSQSMSGTSMAAPHVAGLAAYLMA 360
>sp|P9WEW3|PCH13_PENRB Subtilisin-like serine protease Pen ch
13 OS=Penicillium rubens OX=1108849 PE=1 SV=1
Length=398
Score = 131 bits (328), Expect = 2e-31, Method: Composition-based stats.
Identities = 57/307 (19%), Positives = 102/307 (33%), Gaps = 39/307 (13%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
HF G+ S S + +P V+++E + T V + W L
Sbjct 75 KHFDINGMKGYSASFDDRTVKDIASDPTVKYVEPDMVVNATANVVQRNAPS------WGL 128
Query 125 SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQP 184
S ++ + G GIV+ +D GI+ H D G + G + ND
Sbjct 129 SRISSKKSGATDYVYDSTAGEGIVIYGVDTGIDIGHADFGGRAEWGTNTADND------- 181
Query 185 RYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNP 244
+ N HGT A A GVA A + V++L + + G++
Sbjct 182 ---DTDGNGHGTHTASTAAGSK------FGVAKKASVVAVKVLGADGSGTNSQVIAGMDW 232
Query 245 NHIHIYS-ASWGPEDDGKTVDG-PARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDS 302
S + G ++ G +R +A V G A+GN ++ +
Sbjct 233 AVKDSKSRGATGKSVMNMSLGGAYSRAMNDAAANVVRS-----GVFLSVAAGNEAQDASN 287
Query 303 CNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTE 362
+ N +I+++T ++ S +T ++
Sbjct 288 SSPASAPN---VCTIAASTNSDGSASFTNFGSVVDLYAPGKD-------ITAAYPGGGSK 337
Query 363 SHTGTSA 369
+ +GTS
Sbjct 338 TLSGTSM 344
>sp|P9WEW4|PCH13_PENCH Subtilisin-like serine protease EN45_076310
OS=Penicillium chrysogenum OX=5076 GN=EN45_076310 PE=3
SV=1
Length=398
Score = 131 bits (328), Expect = 2e-31, Method: Composition-based stats.
Identities = 57/307 (19%), Positives = 102/307 (33%), Gaps = 39/307 (13%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
HF G+ S S + +P V+++E + T V + W L
Sbjct 75 KHFDINGMKGYSASFDDRTVKDIASDPTVKYVEPDMVVNATANVVQRNAPS------WGL 128
Query 125 SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQP 184
S ++ + G GIV+ +D GI+ H D G + G + ND
Sbjct 129 SRISSKKSGATDYVYDSTAGEGIVIYGVDTGIDIGHADFGGRAEWGTNTADND------- 181
Query 185 RYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNP 244
+ N HGT A A GVA A + V++L + + G++
Sbjct 182 ---DTDGNGHGTHTASTAAGSK------FGVAKKASVVAVKVLGADGSGTNSQVIAGMDW 232
Query 245 NHIHIYS-ASWGPEDDGKTVDG-PARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDS 302
S + G ++ G +R +A V G A+GN ++ +
Sbjct 233 AVKDSKSRGATGKSVMNMSLGGAYSRAMNDAAANVVRS-----GVFLSVAAGNEAQDASN 287
Query 303 CNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTE 362
+ N +I+++T ++ S +T ++
Sbjct 288 SSPASAPN---VCTIAASTNSDGSASFTNFGSVVDLYAPGKD-------ITAAYPGGGSK 337
Query 363 SHTGTSA 369
+ +GTS
Sbjct 338 TLSGTSM 344
>sp|C5G1D1|SUB5_ARTOC Subtilisin-like protease 5 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB5
PE=3 SV=1
Length=395
Score = 129 bits (323), Expect = 7e-31, Method: Composition-based stats.
Identities = 57/348 (16%), Positives = 117/348 (34%), Gaps = 65/348 (19%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ +P+V ++E ++ V Q+ P W LS ++ R + G G
Sbjct 97 ISNDPKVAFVEPDAI--ISQHVVVQQRKAP-----WGLSRLSNRKGGRNYVFDST-AGAG 148
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D G++ H + G G++ N + HGT AG +A
Sbjct 149 VWAYVVDSGVDIRHAEFRGRAVWGSNQVDNQN----------SDGTGHGTHVAGTIAGKT 198
Query 207 NNGVCGVGVAYNARIGGVRMLD----GEVTDAVEARSLGLNPN------HIHIYSASWGP 256
G+A A++ V++L+ G + + + +N H + + S G
Sbjct 199 ------YGIAKKAKVIAVKVLNSEGKGPTSGIIAGINWSINNARQNGMLHKSVINMSLGG 252
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
A + G ++GN ++ + + +
Sbjct 253 SY-------------SAGLNHATAQAIKAGIFVSVSAGNDNINSNNNSP---ASEKSVCT 296
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAG 376
I+++T+ +S + Y+ G + + ++ +GTS +AP A G
Sbjct 297 IAASTEDDGKASFSNWGPA--VDLYAPG-----HNILSARPGGGSQVMSGTSMAAPHACG 349
Query 377 IIALTLE------ANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ A + + L + + + P NG GR
Sbjct 350 VAAYLIAKEGIPGSRACLRLKQLSQPTIH--NPGPDTTRRLLYNGSGR 395
>sp|A1CIA7|ORYZ_ASPCL Alkaline protease 1 OS=Aspergillus clavatus
(strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL
1 / QM 1276 / 107) OX=344612 GN=alp1 PE=3 SV=1
Length=403
Score = 128 bits (321), Expect = 1e-30, Method: Composition-based stats.
Identities = 56/337 (17%), Positives = 103/337 (31%), Gaps = 42/337 (12%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
++ V +E+ + Y + + W L ++ + G
Sbjct 102 EIRNSEDVAHVEED-------QIWYLDALTTQSGAPWGLGSISHKGQASTNYVYDTSAGA 154
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G ++D GI +H + G + D ++ HGT AG +
Sbjct 155 GTYAYVVDSGINVDHIEFQGRATKAYNAVGGDH----------VDTLGHGTHVAGTI--- 201
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDG 265
G GVA + V++ +G T + G N I S G +
Sbjct 202 ---GGKTYGVAKQTNLLSVKVFEGR-TGSTSVILDGFNWAANDIV--SKGRKGKAAINMS 255
Query 266 PARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGN 325
AF V + G + V A+GN G + + + N+ L++ + +
Sbjct 256 LGGGYSYAFNNAV-ESAYEQGVLSVVAAGNEGVDASNSSPASAPNA---LTVGATNKSNA 311
Query 326 VPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC-TESHTGTSASAPLAAGIIALTL-- 382
+S I++ + T + +GTS + P G+ +
Sbjct 312 RASFSNYGKVLDIFAPGQ------DILSAWIGSTTATNTISGTSMATPHVVGLAVYLMGL 365
Query 383 ---EANKNLTWRDMQHLVVQTSKPAHLNANDWATNGV 416
+T R +Q + N A NG
Sbjct 366 EGVSGPAAVTQRILQLATSGVISDVKGSPNKLAYNGA 402
>sp|D4DIS6|SUB10_TRIVH Subtilisin-like protease 10 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB10 PE=3 SV=1
Length=522
Score = 130 bits (326), Expect = 2e-30, Method: Composition-based stats.
Identities = 73/345 (21%), Positives = 116/345 (34%), Gaps = 55/345 (16%)
Query 51 KHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRD 108
K G F H W G + R S R + + + V +E+ T +
Sbjct 62 KRDVAKRGISFSGIGHSWATG-SFRGYSGVFSRDTIEEIMKHEHVAHVERDQIG--TSQG 118
Query 109 VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYD 168
+P P W L ++ + G VV ++D GI+ HP+ G
Sbjct 119 WVTQPKAPN----WGLGRLSNSNPGNTDYTYDEGAGGNAVVYVIDSGIDTMHPEFQGRAT 174
Query 169 PGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD 228
GA+F + ++ HGT CAG + +V GVA A + V++LD
Sbjct 175 WGANFIDKNN----------VDCWGHGTHCAGIIGSVT------FGVAKRAAMIAVKVLD 218
Query 229 GEVTDAVEARSLGLNPNHIH----------IYSASWGPEDDGKTVDGPARLAEEAFFRGV 278
A GL+ H I + S G + + +A
Sbjct 219 CNGQGPYSAFIAGLHWATEHAQKNGHIGRAIINFSLGGD--------NSPAVNQALEEA- 269
Query 279 SQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLA 338
G A+GN G + S G + I ++ + W + S+ A
Sbjct 270 ----QKAGIFVSAAAGNFGSDAGSITPGG---ARLVCVIGNSDERDYR-WTGQGPSNFGA 321
Query 339 TTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE 383
I++T L + TGTS +AP AG A+ +
Sbjct 322 RVD--IFAPGTDIMST-LPGGGSGVMTGTSMAAPHVAGQAAIQVS 363
>sp|P29805|PRTT_SERMA Extracellular serine protease OS=Serratia
marcescens OX=615 PE=3 SV=1
Length=1045
Score = 132 bits (332), Expect = 2e-30, Method: Composition-based stats.
Identities = 71/384 (18%), Positives = 129/384 (34%), Gaps = 89/384 (23%)
Query 114 TDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASF 173
+ +F +QW L ++ + A+A+ YTG G+ + ++DD I +HP+ AG +
Sbjct 42 KNAEFNRQWGLEAIS-----AEFAYARAYTGKGVTIGVIDDAI-LSHPEFAGKL----TR 91
Query 174 DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVT 232
N + M+ HGT AG +AA +G GVAY+A I G ++ D G
Sbjct 92 LDNGSYNFSYDKQDNMSFGTHGTHVAG-IAAAKRDGSGMHGVAYDADIIGTKLNDYGNRN 150
Query 233 DAVEAR---------SLGLNPN-----HIHIYSASWGPEDDGK----------------- 261
E S G+ P+ I G D
Sbjct 151 GREELIQSAARVINNSWGIRPDIRRDAKGDIIWLPNGRPDYVAWVKTDVINEVMRNKSNL 210
Query 262 ------TVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGR----EHDSCNCDGYTNS 311
V A R G + V+++GN E +
Sbjct 211 EWGSEQPVPTGGHSAMATLLRAAKH-----GKLIVFSAGNYNNYNIPEAQKSLPYAFPEV 265
Query 312 IYT-LSISSATQFGNVPWYSEACSSTL--------ATTYSSGNQ---NEKQIVTTDLRQK 359
+ L +++ + + S +C T ++ YSS + N V + K
Sbjct 266 LNNYLIVTNLSNNDKLSVSSTSCGHTASFLACQPGSSIYSSVGELVSNTGGAVNREAYNK 325
Query 360 C-------TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWA 412
+ +GTS + P G A+ ++ ++ + ++ T+
Sbjct 326 GELTVKPDYGNMSGTSMA-PDVTGFAAVLMQRFPYMSAAQISAVIKTTATDLGEVG---- 380
Query 413 TNGVGRKVSHSYGYGLLDAGAMVA 436
+ H +G+G ++ +
Sbjct 381 -------IDHLFGWGRVNLRDAIN 397
>sp|A1CWF3|ORYZ_NEOFI Alkaline protease 1 OS=Neosartorya fischeri
(strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 /
JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=alp1 PE=2 SV=1
Length=403
Score = 127 bits (319), Expect = 2e-30, Method: Composition-based stats.
Identities = 59/333 (18%), Positives = 104/333 (31%), Gaps = 43/333 (13%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
+++ V +E+ + Y + + W L ++ + G
Sbjct 102 EIRKSADVAHVEED-------QIWYIDALTTQKGAPWGLGSISHKGQASTDYIYDTSAGA 154
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G ++D GI NH + G AS N + ++ HGT AG +
Sbjct 155 GTYAYVVDTGINVNHVEFEGR----ASLAYNAAGG------SHVDSVGHGTHVAGTI--- 201
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDG 265
G GVA + V++ GE + + G N I S G
Sbjct 202 ---GGKTYGVAKKTNLLSVKVFQGESS-STSIILDGFNWAANDIV--SKGRTRKAAINMS 255
Query 266 PARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGN 325
AF V G + V A+GN + + + N+ L++++ +
Sbjct 256 LGGGYSYAFNNAVENAFD-EGVLSVVAAGNENTDASNTSPASAPNA---LTVAAINRSNA 311
Query 326 VPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC-TESHTGTSASAPLAAGIIALTLEA 384
+S S I++ + T + +GTS + P G+ +
Sbjct 312 RASFSNYGSVVDIFAPGQ------DILSAWIGSNTATNTISGTSMATPHIVGLSVYLMGL 365
Query 385 NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVG 417
+ TS+ L N TN G
Sbjct 366 ESLSGPAAV------TSRIKQLATNGVVTNAQG 392
>sp|C5NZT2|SUB4B_COCP7 Subtilisin-like protease CPC735_012930
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_012930
PE=3 SV=1
Length=377
Score = 125 bits (314), Expect = 9e-30, Method: Composition-based stats.
Identities = 66/383 (17%), Positives = 121/383 (32%), Gaps = 72/383 (19%)
Query 34 WAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQV 93
WA + G +R GF + F G S + + V
Sbjct 56 WAANVHHGNLAKQGPSRSIGF---------QFSFDIGGWRGYSGKFDNDTLNAIVNNAHV 106
Query 94 QWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILD 153
+++E T + + W L ++ K G G++ ++D
Sbjct 107 KYVEPDRMASATVLKIQKNAPS------WGLGRISHTFRGFKNYLYHSSAGEGVLAYVVD 160
Query 154 DGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGV 213
GI+ NHP+ G + G + V++ D D ++ HGT AG + G
Sbjct 161 TGIDINHPEFEGRAEWGIN-VVDEVDTD---------EHGHGTHVAGTI------GSKTF 204
Query 214 GVAYNARIGGVRML--DGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAE 271
GVA ++ V+ L D D+ ++ H + A
Sbjct 205 GVAKKVKLVAVKALGKDSRGPDSGIIAAMDWAVKHAKERGILGKAIMNLSLTGDTATALN 264
Query 272 EAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSE 331
EA R V + G A+GN R+ + + + + ++ + +S
Sbjct 265 EAAERAVEE-----GLFLGVAAGNNNRDAINESP---ASVETVCTAGASAENDEKASFSN 316
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWR 391
S TS +AP G+ AL + + + +
Sbjct 317 FGSLR------------------------------TSMAAPHVCGVAALLMSSE-GIKAQ 345
Query 392 DMQHLVVQTSKPAHLNANDWATN 414
+ + + ++PA N + TN
Sbjct 346 EACDRIKKLARPAIRNPGNSTTN 368
>sp|P28296|ORYZ_ASPFU Alkaline protease 1 OS=Aspergillus fumigatus
(strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293)
OX=330879 GN=alp1 PE=1 SV=2
Length=403
Score = 124 bits (312), Expect = 2e-29, Method: Composition-based stats.
Identities = 51/298 (17%), Positives = 94/298 (32%), Gaps = 37/298 (12%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
+++ V +E+ + Y + + W L ++ + G
Sbjct 102 EIRKSADVAHVEED-------QIWYLDALTTQKGAPWGLGSISHKGQASTDYIYDTSAGA 154
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G ++D GI NH + AS N + ++ HGT AG +
Sbjct 155 GTYAYVVDSGINVNHVEFESR----ASLAYNAAGG------SHVDSIGHGTHVAGTI--- 201
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDG 265
G GVA + V++ GE + + G N I S G
Sbjct 202 ---GGKTYGVAKKTNLLSVKVFQGESS-STSIILDGFNWAVNDIV--SKGRTKKAAINMS 255
Query 266 PARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGN 325
AF V G + V A+GN + + + N+ L++++ +
Sbjct 256 LGGGYSYAFNNAVENAFD-EGVLSVVAAGNENSDASNTSPASAPNA---LTVAAINKSNA 311
Query 326 VPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC-TESHTGTSASAPLAAGIIALTL 382
+S S I++ + T + +GTS + P G+ +
Sbjct 312 RASFSNYGSVVDIFAPGQ------DILSAWIGSTTATNTISGTSMATPHIVGLSVYLM 363
>sp|B0Y708|ORYZ_ASPFC Alkaline protease 1 OS=Aspergillus fumigatus
(strain CBS 144.89 / FGSC A1163 / CEA10) OX=451804 GN=alp1
PE=3 SV=1
Length=403
Score = 124 bits (312), Expect = 2e-29, Method: Composition-based stats.
Identities = 51/298 (17%), Positives = 94/298 (32%), Gaps = 37/298 (12%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
+++ V +E+ + Y + + W L ++ + G
Sbjct 102 EIRKSADVAHVEED-------QIWYLDALTTQKGAPWGLGSISHKGQASTDYIYDTSAGA 154
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G ++D GI NH + AS N + ++ HGT AG +
Sbjct 155 GTYAYVVDSGINVNHVEFESR----ASLAYNAAGG------SHVDSIGHGTHVAGTI--- 201
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDG 265
G GVA + V++ GE + + G N I S G
Sbjct 202 ---GGKTYGVAKKTNLLSVKVFQGESS-STSIILDGFNWAVNDIV--SKGRTKKAAINMS 255
Query 266 PARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGN 325
AF V G + V A+GN + + + N+ L++++ +
Sbjct 256 LGGGYSYAFNNAVENAFD-EGVLSVVAAGNENSDASNTSPASAPNA---LTVAAINKSNA 311
Query 326 VPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC-TESHTGTSASAPLAAGIIALTL 382
+S S I++ + T + +GTS + P G+ +
Sbjct 312 RASFSNYGSVVDIFAPGQ------DILSAWIGSTTATNTISGTSMATPHIVGLSVYLM 363
>sp|C5P6L5|SUB4C_COCP7 Subtilisin-like protease CPC735_024010
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_024010
PE=3 SV=1
Length=407
Score = 124 bits (311), Expect = 3e-29, Method: Composition-based stats.
Identities = 68/365 (19%), Positives = 120/365 (33%), Gaps = 42/365 (12%)
Query 63 DYYHFWHRGVTKRSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
H + K S ++ L V ++E D +
Sbjct 76 GVKHTFKINGWK-GYSGSFDENTLHELITNENVDYIEPDRMSHIASLDRKFALETQRNAP 134
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP 180
W L V+ R N + G G+ V +D GI+ HPD G AS+ +N D
Sbjct 135 SWGLGRVSHRQGNSRDYVYDSTAGEGVTVYSIDTGIDIKHPDFEGR----ASWGINTVDD 190
Query 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD--GEVTDAVEAR 238
+ + HGT + + GVA A+I ++ D G D+ +
Sbjct 191 ------IDEDGHGHGTHTSSTIVGKT------YGVAKKAKIIAAKVYDARGRGPDSATLK 238
Query 239 SLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGR 298
++ +H + + + V R + V G A+GN R
Sbjct 239 AIEWAVDHAQKNNHTGKAAMNLSLVTDSPRAVNAVCTKAVE-----AGIFLAVAAGNDNR 293
Query 299 EHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQ 358
+ + ++ ++ + +S L Y+ G Q +T
Sbjct 294 AVTNESP---ASADKVCTVGATRLGDQKAGFSNYG--RLVALYAPG-----QSITAAFPN 343
Query 359 KCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTS-----KPAHLNANDWAT 413
T + +GTS +AP G+ A + A + +T + + + Q + P N
Sbjct 344 GRTGTISGTSMAAPHVCGVGATIM-ALEGVTPQKLCDRLKQLAHPSVRNPGPNTTNKLLY 402
Query 414 NGVGR 418
NG G+
Sbjct 403 NGSGQ 407
>sp|Q03420|ALP_HYPAT Alkaline proteinase OS=Hypocrea atroviridis
OX=63577 GN=prb1 PE=1 SV=1
Length=409
Score = 124 bits (311), Expect = 3e-29, Method: Composition-based stats.
Identities = 53/308 (17%), Positives = 101/308 (33%), Gaps = 32/308 (10%)
Query 86 RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
+++ P V +E + + + W L V+ R + G
Sbjct 94 QIKSNPDVASVEPDYIMHLSDIVEDKRALTTQSGAPWGLGTVSHRTSGSTSYIYDSSAGA 153
Query 146 GIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAV 205
G ++D GI +H G G + ++ HGT +G +
Sbjct 154 GTFAYVVDSGINTSHQQFGGRASLGYN----------AAGGQHVDTLGHGTHVSGTIGGS 203
Query 206 ANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDD-GKTVD 264
GVA A + V++ GE + + G N I S S + ++
Sbjct 204 T------YGVAKQASLISVKVFAGE-SASTSVILDGYNWAVNDIVSKSRASKSAINMSLG 256
Query 265 GPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY--TNSIYTLSISSATQ 322
GPA G + + A+GNG + G N +++++
Sbjct 257 GPASSTWTTAINAAFNQ----GVLTIVAAGNGDSLGNPQPVSGTSPANVPNAITVAALDI 312
Query 323 FGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC-TESHTGTSASAPLAAGIIALT 381
++ + I+++ + T + +GTS + P G +AL
Sbjct 313 NWRTASFTNYGAGVDVFAPG------VNILSSWIGSNTATNTISGTSMATPHVVG-LALY 365
Query 382 LEANKNLT 389
L++ + LT
Sbjct 366 LQSLEGLT 373
>sp|D4D1U5|SUB12_TRIVH Subtilisin-like protease 12 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB12 PE=3 SV=1
Length=397
Score = 124 bits (310), Expect = 3e-29, Method: Composition-based stats.
Identities = 54/343 (16%), Positives = 108/343 (31%), Gaps = 42/343 (12%)
Query 80 HRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWA 139
+ V+++E +++ T + W LS ++ ++ + +
Sbjct 91 DEDTVQEILNHENVEFVEPN-------KEMQVASTIKQGNVTWGLSRISHKENSSHDYVS 143
Query 140 QGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
G I +D GI+ N D G G + + + N HGT A
Sbjct 144 TYGEGENITFYGIDSGIDINQADFTGRARWGIN----------LADHVDTDCNGHGTHTA 193
Query 200 GEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDD 259
G VA G+ A I +++LD + GLN
Sbjct 194 GTVAGQK------FGILKKASIVSIKILDCYGYGDITRYINGLNWAINDAKERGL---LG 244
Query 260 GKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISS 319
++ + + G A+GN + + ++ ++ +
Sbjct 245 KSVMNISLKTGRSRAVNEATVRAQEAGIFIAVAAGNQATSAEFYSP---GSAPEVCTVGA 301
Query 320 ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIA 379
+T+ +S L ++ ++ + + L T +GTS + P G+
Sbjct 302 STRNDTKAIFSNYG--ELVDLFA-----PREYIRSTLPHNLTGLMSGTSMATPHVCGVGG 354
Query 380 LTLEANKNLTWRDMQHLVVQTSKPAHLN-----ANDWATNGVG 417
L + A + L + + + + P N N NG G
Sbjct 355 LIM-ATEGLAPEKVCDRLKELANPTIQNPGFNTTNKLLYNGSG 396
>sp|E4UZP9|SUB2_ARTGP Subtilisin-like protease 2 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB2
PE=3 SV=1
Length=422
Score = 124 bits (311), Expect = 4e-29, Method: Composition-based stats.
Identities = 64/361 (18%), Positives = 116/361 (32%), Gaps = 46/361 (13%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
HF + S L R P V+ + + VY T + +W L
Sbjct 83 KHFHIHNLNMYSGGFDEKTAEELSRNPYVKSVHPD-------QHVYLAKTVTQPQARWGL 135
Query 125 SGVTQRDLNVK------AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ 178
++ + V G G+ +LD GI NH + G G
Sbjct 136 GYMSSKGKPVPLHSTLVDYLYDDKAGEGVWAYVLDTGINVNHVEFEGRGILG-------- 187
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAVEA 237
+ P ++ HGT AG +A GVA A + + D G T
Sbjct 188 -HNAIPNKPHTDEFGHGTYVAGIIAGKT------YGVAKKANVVSAKAFDTGSSTYNYIL 240
Query 238 RSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGG 297
+ +I + + ++ A+ F + G V A+GN G
Sbjct 241 ETYDWIVRNITDSN-----RKNKAVINLSISGAKYQPFDDAVENAFKAGITTVVAAGNDG 295
Query 298 REHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLR 357
++ + N+I ++ + P +S +++ + +
Sbjct 296 KDAKNNTPASSPNAI---TVGAVRWENTRPSFSNYGKIVDIWAPG-------ELIKSCWK 345
Query 358 QKCTESHT--GTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNG 415
T + T GTSA++P AG++A + + + V+ + P + + N
Sbjct 346 GSNTATSTQSGTSAASPHVAGLVAYLMSFENLPSPSAVTARVLNLTIPNLVKDAKDSPNR 405
Query 416 V 416
V
Sbjct 406 V 406
>sp|D4AQA9|SUB12_ARTBC Subtilisin-like protease 12 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331
GN=SUB12 PE=3 SV=1
Length=416
Score = 124 bits (311), Expect = 4e-29, Method: Composition-based stats.
Identities = 56/355 (16%), Positives = 110/355 (31%), Gaps = 47/355 (13%)
Query 80 HRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWA 139
+ V+++E +++ T + W LS ++ ++ + +
Sbjct 91 DEDTVQEILNHENVEFVEPN-------KEMQVASTIKQGNVTWGLSRISHKENSSHDYVS 143
Query 140 QGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
G I +D GI+ N D G G + + + N HGT A
Sbjct 144 TYGEGENITFYGIDSGIDINQADFTGRARWGIN----------LADHVDTDCNGHGTHTA 193
Query 200 GEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDD 259
G VA G+ A I +++LD + GLN
Sbjct 194 GTVAGQK------FGILKKASIVSIKILDCYGYGDITRYINGLNWAINDAKERGL---LG 244
Query 260 GKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISS 319
++ + + G A+GN + + ++ ++ +
Sbjct 245 KSVMNISLKTRRSRAVNEATVRAQEAGIFIAVAAGNQATSAEFYSP---GSAPEVCTVGA 301
Query 320 ATQFGNVPWYSE----ACSSTLATTYSSGNQNEKQI--------VTTDLRQKCTESHTGT 367
+T+ +S S + Y++G + + + L T +GT
Sbjct 302 STRNDTKAIFSNYGELGMSWSCILFYTTGTNVNHTVDLFAPGEYIRSTLPHNLTGLMSGT 361
Query 368 SASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN-----ANDWATNGVG 417
S + P G+ L + A + L + + + + P N N NG G
Sbjct 362 SMATPHVCGVGGLIM-ATEGLAPEKVCDRLKELANPTIQNPGFNTTNKLLYNGSG 415
>sp|Q64K35|SUB2_ARTBE Subtilisin-like protease 2 OS=Arthroderma
benhamiae OX=63400 GN=SUB2 PE=3 SV=2
Length=419
Score = 124 bits (310), Expect = 4e-29, Method: Composition-based stats.
Identities = 65/361 (18%), Positives = 119/361 (33%), Gaps = 46/361 (13%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
HF + S L R P V+ + + VY T + +W L
Sbjct 82 KHFHIHDLNMYSGGFDEKTVEDLSRNPYVKSVHPD-------QHVYLAKTVTQRQARWGL 134
Query 125 SGVTQRDLNVK------AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ 178
++ + V G G+ +LD GI NH + G G
Sbjct 135 GYMSSKGKPVPLHSTLVDYSYDDKAGEGVWAYVLDTGINVNHVEFEGRGILG-------- 186
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAVEA 237
+ P ++ HGT AG +A GVA A + + D G T
Sbjct 187 -HNAIPNKPHTDEFGHGTYVAGIIAGKT------YGVAKKANVVSAKAFDTGSSTYNYIL 239
Query 238 RSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGG 297
+ +I + + ++ A+ F + G V A+GN G
Sbjct 240 ETYDWIVRNITDSN-----RKNKAVINLSISGAKYQPFDDAVEKAFKAGITTVVAAGNDG 294
Query 298 REHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL- 356
++ + N+I ++ + P +S L ++ G +++ +
Sbjct 295 KDAKNNTPASSPNAI---TVGAVRWENTRPSFSNYGK--LVDIWAPG-----ELIKSCWK 344
Query 357 -RQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNG 415
T + +GTSA++P AG++A + + + V+ + P + + N
Sbjct 345 GGNNATSTQSGTSAASPHVAGLVAYLMSIENLPSPSAVTARVLNLTIPNLVKDAKDSPNR 404
Query 416 V 416
V
Sbjct 405 V 405
>sp|D4AZ75|SUB2_ARTBC Subtilisin-like protease 2 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB2
PE=2 SV=2
Length=421
Score = 124 bits (310), Expect = 5e-29, Method: Composition-based stats.
Identities = 65/361 (18%), Positives = 119/361 (33%), Gaps = 46/361 (13%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
HF + S L R P V+ + + VY T + +W L
Sbjct 82 KHFHIHDLNMYSGGFDEKTVEDLSRNPYVKSVHPD-------QHVYLAKTVTQRQARWGL 134
Query 125 SGVTQRDLNVK------AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ 178
++ + V G G+ +LD GI NH + G G
Sbjct 135 GYMSSKGKPVPLHSTLVDYSYDDKAGEGVWAYVLDTGINVNHVEFEGRGILG-------- 186
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAVEA 237
+ P ++ HGT AG +A GVA A + + D G T
Sbjct 187 -HNAIPNKPHTDEFGHGTYVAGIIAGKT------YGVAKKANVVSAKAFDTGSSTYNYIL 239
Query 238 RSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGG 297
+ +I + + ++ A+ F + G V A+GN G
Sbjct 240 ETYDWIVRNITDSN-----RKNKAVINLSISGAKYQPFDDAVEKAFKAGITTVVAAGNDG 294
Query 298 REHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL- 356
++ + N+I ++ + P +S L ++ G +++ +
Sbjct 295 KDAKNNTPASSPNAI---TVGAVRWENTRPSFSNYGK--LVDIWAPG-----ELIKSCWK 344
Query 357 -RQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNG 415
T + +GTSA++P AG++A + + + V+ + P + + N
Sbjct 345 GGNNATSTQSGTSAASPHVAGLVAYLMSIENLPSPSAVTARVLNLTIPNLVKDAKDSPNR 404
Query 416 V 416
V
Sbjct 405 V 405
>sp|C5NZ69|SUB7C_COCP7 Subtilisin-like protease CPC735_013700
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_013700
PE=3 SV=1
Length=400
Score = 123 bits (309), Expect = 5e-29, Method: Composition-based stats.
Identities = 51/312 (16%), Positives = 109/312 (35%), Gaps = 59/312 (19%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNV---KAAWAQG 141
R+ +EP V ++E ++ V + W L ++ ++ + +
Sbjct 96 QRIAKEPDVAFIEPNQIVTISEISVQKAAPS------WGLPRISVKENQLSSNTDYFYDS 149
Query 142 YTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGE 201
G GI V ++D G++ HPD G G S + + HGT AG
Sbjct 150 SAGAGIWVYVVDTGVDIKHPDFEGRAVWGTSTVDRSK----------TDRLGHGTHVAGT 199
Query 202 VAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN-------PNHI---HIYS 251
+A+ GVA +I V++ + T + + G++ N++ + +
Sbjct 200 IASKT------YGVAKAVKIIAVKVF-KDRTTSYKNIIGGIDWAVKHSKKNNMLSKSVVN 252
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
S G G + +A G ++GN D+ N +
Sbjct 253 MSLG--------GGRSSAMNKAAANA-----HKTGMFVAVSAGN--TPVDAMNFSPASEP 297
Query 312 IYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASA 371
+ +++++ + +S + + + + + +K + +GTS +A
Sbjct 298 LAC-TVAASDKDDMQAQFSAFGPAVDIFAPGTD-------IVSLVPRKKFGTKSGTSMAA 349
Query 372 PLAAGIIALTLE 383
+G A +
Sbjct 350 AHVSGAGAYIMA 361
>sp|Q5VJ76|SUB2_TRIVC Subtilisin-like protease 2 OS=Trichophyton
verrucosum OX=63417 GN=SUB2 PE=3 SV=2
Length=419
Score = 123 bits (309), Expect = 6e-29, Method: Composition-based stats.
Identities = 65/361 (18%), Positives = 119/361 (33%), Gaps = 46/361 (13%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
HF + S L R P V+ + + VY T + +W L
Sbjct 82 KHFHIHDLNMYSGGFDEKTVEDLSRNPYVKSVHPD-------QHVYLAKTVTQRQARWGL 134
Query 125 SGVTQRDLNVK------AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ 178
++ + V G G+ +LD GI NH + G G
Sbjct 135 GYMSSKGKPVPLHSTLVDYSYDDKAGEGVWAYVLDTGINVNHIEFEGRAILG-------- 186
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAVEA 237
+ P ++ HGT AG +A GVA A + + D G T
Sbjct 187 -HNAIPNKPHTDEFGHGTYVAGIIAGKT------YGVAKKANVVSAKAFDTGSSTYNYIL 239
Query 238 RSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGG 297
+ +I + + ++ A+ F + G V A+GN G
Sbjct 240 ETYDWIVRNITDSN-----RKNKAVINLSISGAKYQPFDDAVEKAFKAGITTVVAAGNDG 294
Query 298 REHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL- 356
++ + N+I ++ + P +S L ++ G +++ +
Sbjct 295 KDAKNNTPASSPNAI---TVGAVRWENTRPSFSNYGK--LVDIWAPG-----ELIKSCWK 344
Query 357 -RQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNG 415
T + +GTSA++P AG++A + + + V+ + P + + N
Sbjct 345 GGNNATSTQSGTSAASPHVAGLVAYLMSIENLPSPSAVTARVLNLTIPNLVKDAKDSPNR 404
Query 416 V 416
V
Sbjct 405 V 405
>sp|D4DLI5|SUB2_TRIVH Subtilisin-like protease 2 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB2 PE=3 SV=2
Length=421
Score = 123 bits (309), Expect = 7e-29, Method: Composition-based stats.
Identities = 65/361 (18%), Positives = 119/361 (33%), Gaps = 46/361 (13%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
HF + S L R P V+ + + VY T + +W L
Sbjct 82 KHFHIHDLNMYSGGFDEKTVEDLSRNPYVKSVHPD-------QHVYLAKTVTQRQARWGL 134
Query 125 SGVTQRDLNVK------AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ 178
++ + V G G+ +LD GI NH + G G
Sbjct 135 GYMSSKGKPVPLHSTLVDYSYDDKAGEGVWAYVLDTGINVNHIEFEGRAILG-------- 186
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAVEA 237
+ P ++ HGT AG +A GVA A + + D G T
Sbjct 187 -HNAIPNKPHTDEFGHGTYVAGIIAGKT------YGVAKKANVVSAKAFDTGSSTYNYIL 239
Query 238 RSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGG 297
+ +I + + ++ A+ F + G V A+GN G
Sbjct 240 ETYDWIVRNITDSN-----RKNKAVINLSISGAKYQPFDDAVEKAFKAGITTVVAAGNDG 294
Query 298 REHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL- 356
++ + N+I ++ + P +S L ++ G +++ +
Sbjct 295 KDAKNNTPASSPNAI---TVGAVRWENTRPSFSNYGK--LVDIWAPG-----ELIKSCWK 344
Query 357 -RQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNG 415
T + +GTSA++P AG++A + + + V+ + P + + N
Sbjct 345 GGNNATSTQSGTSAASPHVAGLVAYLMSIENLPSPSAVTARVLNLTIPNLVKDAKDSPNR 404
Query 416 V 416
V
Sbjct 405 V 405
>sp|B6VA85|SUB2_TRIEQ Subtilisin-like protease 2 OS=Trichophyton
equinum OX=63418 GN=SUB2 PE=3 SV=1
Length=421
Score = 123 bits (309), Expect = 8e-29, Method: Composition-based stats.
Identities = 63/359 (18%), Positives = 114/359 (32%), Gaps = 42/359 (12%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
HF + S L R P V+ + + VY T + +W L
Sbjct 82 KHFHIHDLNMYSGGFDEKTVEDLSRNPYVKSVHPD-------QHVYLAKTVTQRQARWGL 134
Query 125 SGVTQRDLNVK------AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ 178
++ + V G G+ +LD GI NH + G G
Sbjct 135 GYMSSKGKPVPLHSTLVDYSYDDKAGEGVWAYVLDTGINVNHVEFEGRAILG-------- 186
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAVEA 237
+ P ++ HGT AG +A GVA A + + D G T
Sbjct 187 -HNAIPNKPHTDEFGHGTYVAGIIAGKT------YGVAKKANVVSAKAFDTGSSTYNYIL 239
Query 238 RSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGG 297
+ +I + + ++ A+ F + G V A+GN G
Sbjct 240 ETYDWIVRNITDSN-----RKNKAVINLSISGAKYQPFDDAVEKAFKAGIATVVAAGNDG 294
Query 298 REHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLR 357
++ + N+I ++ + P +S ++ +
Sbjct 295 KDAKNNTPASSPNAI---TVGAVRWENTRPSFSNYGKIVDIWAPGELIKSCWKG-----G 346
Query 358 QKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGV 416
T + +GTSA++P AG++A + + + V+ + P + + N V
Sbjct 347 NNATSTQSGTSAASPHVAGLVAYLMSTENLPSPSAVTARVLNLTIPNLVKDAKDSPNRV 405
>sp|Q69F57|SUB2_TRIRU Subtilisin-like protease 2 OS=Trichophyton
rubrum OX=5551 GN=SUB2 PE=3 SV=2
Length=421
Score = 123 bits (308), Expect = 8e-29, Method: Composition-based stats.
Identities = 62/359 (17%), Positives = 115/359 (32%), Gaps = 42/359 (12%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
HF + S R L R P V+ + K ++ +W L
Sbjct 82 KHFHIHDLNMYSGGFDEKRVEDLSRSPYVKSVHPDQHFYLAKTVTQRQA-------RWGL 134
Query 125 SGVTQRDLNVK------AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ 178
++ + V G G+ +LD GI NH + G G
Sbjct 135 GYMSSKGKPVPLHSTLVDYSYDDKAGEGVWAYVLDTGINVNHVEFEGRAILG-------- 186
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAVEA 237
+ P + ++ HGT AG +A GVA A + + D G T
Sbjct 187 -HNAIPNKSHTDEFGHGTCVAGIIAGKT------YGVAKKANVVSAKAFDTGSSTYNYIL 239
Query 238 RSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGG 297
+ +I + + ++ A+ F ++ G V A+GN G
Sbjct 240 ETYDWIIRNITDSN-----RKNKAVINLSISGAKYQPFDDAAERAFKAGITTVVAAGNDG 294
Query 298 REHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLR 357
++ + N+I ++ + P +S ++ +
Sbjct 295 KDAKNNTPASSPNAI---TVGAVRWENTRPSFSNYGKIVDIWAPGELIKSCWKG-----G 346
Query 358 QKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGV 416
T + +GTSA++P AG++A + + + V+ + P + + N V
Sbjct 347 NNATSTQSGTSAASPHVAGLVAYLMSIKNLPSPSAVTARVLNLTIPNLVKDAKDSPNRV 405
>sp|B8XGQ5|SUB2_TRITO Subtilisin-like protease 2 OS=Trichophyton
tonsurans OX=34387 GN=SUB2 PE=3 SV=2
Length=421
Score = 123 bits (308), Expect = 9e-29, Method: Composition-based stats.
Identities = 63/359 (18%), Positives = 114/359 (32%), Gaps = 42/359 (12%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
HF + S L R P V+ + + VY T + +W L
Sbjct 82 KHFHIHDLNMYSGGFDEKTVEDLSRNPYVKSVHPD-------QHVYLAKTVTQRQARWGL 134
Query 125 SGVTQRDLNVK------AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ 178
++ + V G G+ +LD GI NH + G G
Sbjct 135 GYMSSKGKPVPLHSTLVDYSYDDKAGEGVWAYVLDTGINVNHVEFEGRAILG-------- 186
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAVEA 237
+ P ++ HGT AG +A GVA A + + D G T
Sbjct 187 -HNAIPNKPHTDEFGHGTYVAGIIAGKT------YGVAKKANVVSAKAFDTGSSTYNYIL 239
Query 238 RSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGG 297
+ +I + + ++ A+ F + G V A+GN G
Sbjct 240 ETYDWIVRNITDSN-----RKNKAVINFSISGAKYQPFDDAVEKAFKAGIATVVAAGNDG 294
Query 298 REHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLR 357
++ + N+I ++ + P +S ++ +
Sbjct 295 KDAKNNTPASSPNAI---TVGAVRWENTRPSFSNYGKIVDIWAPGELIKSCWKG-----G 346
Query 358 QKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGV 416
T + +GTSA++P AG++A + + + V+ + P + + N V
Sbjct 347 NNATSTQSGTSAASPHVAGLVAYLMSTENLPSPSAVTARVLNLTIPNLVKDAKDSPNRV 405
>sp|Q00208|ORYZ_EMENI Alkaline protease 1 OS=Emericella nidulans
(strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
OX=227321 GN=alp1 PE=2 SV=1
Length=403
Score = 123 bits (307), Expect = 1e-28, Method: Composition-based stats.
Identities = 58/352 (16%), Positives = 107/352 (30%), Gaps = 43/352 (12%)
Query 33 TWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQ 92
+WA + + G Q G ++ S S ++
Sbjct 54 SWASNVHK------RNLERRGLAERDQYSGIEKNYKINKFAAYSGSFDDATIEEIRNSAD 107
Query 93 VQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSIL 152
V +E+ + Y + + W L ++ + G G ++
Sbjct 108 VAHVEED-------QIWYIDALTSQSGAPWGLGAISHKGEASTTYVYDTSAGEGTYAYVV 160
Query 153 DDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCG 212
D GI +H + G AS N ++ HGT AG +
Sbjct 161 DTGINADHEEFGGR----ASLAYN------AVGGQHVDSVGHGTHVAGTIGGET------ 204
Query 213 VGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEE 272
GV+ A + V++ GE + + G N I S G
Sbjct 205 YGVSKKANLLSVKVFQGESS-STSIILDGFNWAANDIV--SKGRTGKSAINMSLGGGYSY 261
Query 273 AFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEA 332
AF + V G + V A+GN + + N+ L+++++T+ +S
Sbjct 262 AFNQAVEDAYD-EGVLSVVAAGNDNIDASDSSPASAPNA---LTVAASTKSNTRASFSNY 317
Query 333 CSSTLATTYSSGNQNEKQIVTTDLRQKC-TESHTGTSASAPLAAGIIALTLE 383
S I++ + T + +GTS + P G+ +
Sbjct 318 GSVVDIFAPGQ------DILSAWIGSTTATNTISGTSMATPHVVGLSLYLIA 363
>sp|C5NZ70|SUB2C_COCP7 Subtilisin-like protease CPC735_013710
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_013710
PE=3 SV=1
Length=407
Score = 122 bits (306), Expect = 1e-28, Method: Composition-based stats.
Identities = 62/371 (17%), Positives = 113/371 (30%), Gaps = 68/371 (18%)
Query 64 YYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWY 123
+ HF + + + L+R P V+ + + +Y + W
Sbjct 74 FKHFQIHKLNMYAAGLDKKTVEELRRSPHVKSVLPD-------QKIYLAEAVTQSNAGWN 126
Query 124 LSGVTQRDLN------VKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVND 177
L ++ + + G G+ +LD G+ NH + G G + N
Sbjct 127 LGYMSSKGQPSPSWSTLTNYTYDSTAGEGVWAYVLDTGVNVNHVEFEGRAILGRNSIPNR 186
Query 178 QDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG------EV 231
D HGT G +A GVA A + + DG +
Sbjct 187 PHEDTF---------GHGTYVGGIIAGKT------YGVAKKATVVSAKAFDGGSSSYRYI 231
Query 232 TDAVEARSLGLNPNHIH---IYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
D+ E + + + + S G E AF G
Sbjct 232 LDSYEWIVKNITDSDRKSKSVINLSIS----GAKYQPFDEAIENAFQ---------AGIT 278
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNE 348
V ASGN GR+ N+I ++ + P +S
Sbjct 279 TVVASGNDGRDASQNTPASSPNAI---TVGALRWENTRPGFSNYGKVVDLFAPG------ 329
Query 349 KQIVTTDL--RQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
+++ + T +GTSA++P AG++A + + ++ T++ +L
Sbjct 330 -ELIRSGWTGGNNATRVASGTSAASPHVAGLVAYLMSIETLSSPSEV------TARVLNL 382
Query 407 NANDWATNGVG 417
+ G
Sbjct 383 TIPGLVKDARG 393
>sp|Q9Y778|SMP1_MAGPO Subtilisin-like proteinase Mp1 OS=Magnaporthiopsis
poae OX=148304 PE=1 SV=1
Length=404
Score = 122 bits (306), Expect = 1e-28, Method: Composition-based stats.
Identities = 55/376 (15%), Positives = 113/376 (30%), Gaps = 51/376 (14%)
Query 23 DAQGQKVFTNTWAVRIPGGPAVA-------------NSVARKHGFLNLGQIFG-DYYHFW 68
D Q +V N++ + + G + A K + ++F D + +
Sbjct 23 DKQATQVVPNSYIITLKQGASAASFHNHLSWVGDVHRRSVSKRDTTGVDKVFDLDGFTAY 82
Query 69 HRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVT 128
+L +++ +V ++E + W L ++
Sbjct 83 SGSFDAATL-------QEIKKSDEVAFVEPDQVWDLYTLS-------TQSGAPWGLGSIS 128
Query 129 QRDLNVKAA-WAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYT 187
R N + G I+D G++ H + G G + P
Sbjct 129 HRKPNSTDYVYDPAGLGADHYAYIIDTGLDTEHVEFEGRGTLGYN---------AYPNSQ 179
Query 188 QMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHI 247
++ HGT AG +A GVA A I VR+ D ++ L+
Sbjct 180 FIDKIGHGTHVAGTIAGKT------YGVAKKASIVSVRVFDTGSVTRQSTTAIVLDGFSW 233
Query 248 HIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDG 307
+ + + F + + V A+GN + +
Sbjct 234 AVKDITAKGRQAKSVISMSLGGGRSEAFNAAVEAAYQANILTVAAAGNSAWDASQYSPAS 293
Query 308 YTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGT 367
N+I ++ + + W+S + ++ G E + + + GT
Sbjct 294 APNAI---TVGAIDVDNVMAWFSNYGP--VVDVFAPGVAVESAWIGSS--HAEHDVLDGT 346
Query 368 SASAPLAAGIIALTLE 383
S + P +G++
Sbjct 347 SMATPHVSGLVLYLKS 362
>sp|Q8J0D9|SUB1_ARTOT Subtilisin-like protease 1 OS=Arthroderma
otae OX=63405 GN=SUB1 PE=3 SV=1
Length=485
Score = 124 bits (310), Expect = 1e-28, Method: Composition-based stats.
Identities = 68/378 (18%), Positives = 131/378 (35%), Gaps = 65/378 (17%)
Query 18 VLLAADAQGQKVFTNT--WAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKR 75
+++ D ++ FT+ W I ++V R+ N G + + + +
Sbjct 36 IVVMKDGTTKEDFTHHQSWVQSIH-----THNVTRRGLLDNAG---VRHKYGFGSMMGYA 87
Query 76 SLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVK 135
L + +P+V ++E T ++ E T P W L+ ++ + +
Sbjct 88 GLF-DEDTIKDISDDPKVMFVEPD-----TTITIHGELTQNDVPS-WGLARISSQRPGTE 140
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHG 195
G GI V +D G++ +H D G G + + D D N HG
Sbjct 141 DYTYDSSAGEGITVYSVDTGVDIHHEDFEGRASWGTNMIEDGYDKD---------GNGHG 191
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN--PNHI------ 247
T AG + G+A A++ V++LD + G+N H
Sbjct 192 THTAGTMVGKT------FGIAKKAKVVAVKVLDNNGSGPTSGIIAGINWCAQHASQNGGT 245
Query 248 --HIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNC 305
+ + S G G + A + V G A+GN ++ + +
Sbjct 246 DKAVINMSLG--------GGSSSALNRAAAQAVQ-----KGMFLAVAAGNDNQDARTSSP 292
Query 306 DGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHT 365
+ ++ ++ + +S + S IV+T +S +
Sbjct 293 ---ASEDTVCTVGASAENDERSSFSNWGPAVDLFAPGS------NIVSTRPGGGS-QSMS 342
Query 366 GTSASAPLAAGIIALTLE 383
GTS ++P AG+ A +
Sbjct 343 GTSMASPHVAGLGAYIMA 360
>sp|C5FPS1|SUB1_ARTOC Subtilisin-like protease 1 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB1
PE=3 SV=1
Length=485
Score = 124 bits (310), Expect = 1e-28, Method: Composition-based stats.
Identities = 68/378 (18%), Positives = 131/378 (35%), Gaps = 65/378 (17%)
Query 18 VLLAADAQGQKVFTNT--WAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKR 75
+++ D ++ FT+ W I ++V R+ N G + + + +
Sbjct 36 IVVMKDGTTEEDFTHHQSWVQSIH-----THNVTRRGLLDNAG---VRHKYGFGSMMGYA 87
Query 76 SLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVK 135
L + +P+V ++E T ++ E T P W L+ ++ + +
Sbjct 88 GLF-DEDTIKDISDDPKVMFVEPD-----TTITIHGELTQNDVPS-WGLARISSQRPGTE 140
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHG 195
G GI V +D G++ +H D G G + + D D N HG
Sbjct 141 DYTYDSSAGEGITVYSVDTGVDIHHEDFEGRASWGTNMIEDGYDKD---------GNGHG 191
Query 196 TRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLN--PNHI------ 247
T AG + G+A A++ V++LD + G+N H
Sbjct 192 THTAGTMVGKT------FGIAKKAKVVAVKVLDNNGSGPTSGIIAGINWCAQHASQNGGT 245
Query 248 --HIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNC 305
+ + S G G + A + V G A+GN ++ + +
Sbjct 246 DKAVINMSLG--------GGSSSALNRAAAQAVQ-----KGMFLAVAAGNDNQDARTSSP 292
Query 306 DGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHT 365
+ ++ ++ + +S + S IV+T +S +
Sbjct 293 ---ASEDTVCTVGASAENDERSSFSNWGPAVDLFAPGS------NIVSTRPGGGS-QSMS 342
Query 366 GTSASAPLAAGIIALTLE 383
GTS ++P AG+ A +
Sbjct 343 GTSMASPHVAGLGAYIMA 360
>sp|C5G168|SUB2_ARTOC Subtilisin-like protease 2 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB2
PE=3 SV=1
Length=423
Score = 121 bits (304), Expect = 3e-28, Method: Composition-based stats.
Identities = 70/416 (17%), Positives = 131/416 (31%), Gaps = 56/416 (13%)
Query 22 ADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHR 81
A + + V + G A A K ++ Q D + GV + +
Sbjct 26 LRAGPSDIVPGQYIVTLKEGLASAQIREHKKWVSSVHQANLDSFAAGASGVETVGIMKNF 85
Query 82 PRHSR--------------LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGV 127
H+ L+R P V+ + + VY T + +W L +
Sbjct 86 HIHNLNMYSGGFDDKTAEDLRRSPDVKSVHPD-------QHVYLAKTVTQPQARWGLGYM 138
Query 128 TQRDLNVK------AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
+ + V G G+ +LD GI +H + G G +
Sbjct 139 SSKGKPVPLHSTLVDYLYDDKAGEGVWAYVLDTGINVDHIEFEGRGILG---------HN 189
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAVEARSL 240
P ++ HGT AG +A GVA A + + D G T +
Sbjct 190 AIPNKPHTDEFGHGTYVAGIIAGKT------YGVAKKANVVSAKAFDTGSSTYNYILETY 243
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
+I + + ++ A+ F + G V A+GN G++
Sbjct 244 DWIVKNITDSN-----RKNKAVINLSISGAKYQPFDDAVENAFKAGITTVVAAGNDGKDA 298
Query 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
+ N+I ++ + P +S ++ +
Sbjct 299 KNNTPASSPNAI---TVGAVRWENTRPSFSNYGKIVDIWAPGELIKSCWKG-----GNNA 350
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGV 416
T + +GTSA++P AG++A + + + V+ + P + + N V
Sbjct 351 TSTQSGTSAASPHVAGLVAYLMSLENLPSPSAVTARVLNLTIPNLVKDAKDSPNRV 406
>sp|P25381|RRT12_YEAST Subtilase-type proteinase RRT12 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=RRT12 PE=1 SV=1
Length=491
Score = 123 bits (307), Expect = 3e-28, Method: Composition-based stats.
Identities = 53/310 (17%), Positives = 100/310 (32%), Gaps = 47/310 (15%)
Query 98 QQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIE 157
+ +A+ + + D + W+ + Y G + I+D GI
Sbjct 130 RHLARISRHYQLPFDVGDKDRYKSWF-----------NYYYEHDYQGQDVNAYIMDTGIF 178
Query 158 KNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAY 217
+HP+ G + + N HGT AG V G G A
Sbjct 179 ADHPEFEDRVIQGID----------LTKEGFGDQNGHGTHVAGLV------GSKTYGAAK 222
Query 218 NARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRG 277
+ V++L + + GL H S P+ +
Sbjct 223 RVNLVEVKVLGKDGSGEASNVLSGLEFIVEHCTKVS-RPQGKKCVANLSLGSFRSPIINM 281
Query 278 VSQGRGGLGSIFVWASGNGGREHDSCNCDGY----TNSIYTLSISSATQF-GNVPWYSEA 332
+G G +FV A+GN N D Y ++ +++ + + +S
Sbjct 282 AVEGAIEEGIVFVAAAGN-------FNLDAYWASPASAENVITVGAFDDHIDTIAKFSNW 334
Query 333 CSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEAN--KNLTW 390
++ G + E + L T +GTS S P+ G+ A+ L +
Sbjct 335 GP--CVNIFAPGVEIES---LSHLNYNDTLILSGTSMSTPIVTGVAAILLSKGIEPEMIA 389
Query 391 RDMQHLVVQT 400
+++++L +
Sbjct 390 QEIEYLSTRN 399
>sp|P09230|AEP_YARLI Alkaline extracellular protease OS=Yarrowia
lipolytica (strain CLIB 122 / E 150) OX=284591 GN=XPR2 PE=1
SV=1
Length=454
Score = 122 bits (305), Expect = 3e-28, Method: Composition-based stats.
Identities = 71/341 (21%), Positives = 116/341 (34%), Gaps = 41/341 (12%)
Query 80 HRPRHSRLQREPQ-VQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNV-KAA 137
S L EP + L + A KR + P QW LS ++ + A
Sbjct 129 KLKESSVLTVEPDTIVSLPEIPASSNAKRAIQTTP-----VTQWGLSRISHKKAQTGNYA 183
Query 138 WAQGYTGHGIVV-SILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGT 196
+ + G V ++D GI H + G GA+F HGT
Sbjct 184 YVRETVGKHPTVSYVVDSGIRTTHSEFGGRAVWGANFADTQNADLL----------GHGT 233
Query 197 RCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGP 256
AG V G GV N ++ V++ G + A+ + G S
Sbjct 234 HVAGTV------GGKTYGVDANTKLVAVKVFAGR-SAALSVINQGFTWALNDYISKRDTL 286
Query 257 EDDGKTV--DGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCD-----GYT 309
GP +++A + +Q G + A+GN D+CN G T
Sbjct 287 PRGVLNFSGGGPKSASQDALWSRATQ----EGLLVAIAAGNDAV--DACNDSPGNIGGST 340
Query 310 NSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSA 369
+ I +++ S + +S S T I + T ++GTS
Sbjct 341 SGI--ITVGSIDSSDKISVWSGGQGSNYGTCVDVFAPGSDIISASYQSDSGTLVYSGTSM 398
Query 370 SAPLAAGIIALTLEANKN-LTWRDMQHLVVQTSKPAHLNAN 409
+ P AG+ + L N LT ++ L+ +++ N
Sbjct 399 ACPHVAGLASYYLSINDEVLTPAQVEALITESNTGVLPTTN 439
>sp|D4AQG0|SUB10_ARTBC Subtilisin-like protease 10 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331
GN=SUB10 PE=3 SV=2
Length=522
Score = 122 bits (305), Expect = 7e-28, Method: Composition-based stats.
Identities = 69/346 (20%), Positives = 111/346 (32%), Gaps = 57/346 (16%)
Query 51 KHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRD 108
K G F H W G + R S R + + + V +E+
Sbjct 62 KRDVAKRGISFSGIGHSWATG-SFRGYSGVFSRDTIEEIMKHEHVAHVERDQIGTSQGWV 120
Query 109 VYQEPTDPKFPQQWYLSGVTQRDL-NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNY 167
+ W L ++ N + + G+G+ V ++D GI+ HP+ G
Sbjct 121 TQSGAPN------WGLGRLSNNSPGNTDYTYDENAGGNGV-VYVIDSGIDTMHPEFQGRA 173
Query 168 DPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
GA+F + ++ HGT CAG + G GVA + V++L
Sbjct 174 TWGANFIDKNN----------VDCWNHGTHCAGII------GSATFGVAKLTALIAVKVL 217
Query 228 DGEVTDAVEARSLGLNPNHIH----------IYSASWGPEDDGKTVDGPARLAEEAFFRG 277
D A GL+ H I + S G + + +A
Sbjct 218 DCNGQGPYSAFVAGLHWATKHAQDNGFIGRAIINFSLGGD--------NSPAVNQALEEA 269
Query 278 VSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTL 337
G A+GN G + S G I ++ W + S+
Sbjct 270 -----QRAGIFVSAAAGNFGSDAGSITPGGAG---LICVIGNSDDRDYR-WTGQGPSNFG 320
Query 338 ATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE 383
A I++T + + TGTS +AP AG A+
Sbjct 321 ARVD--IFAPGTNILST-IPGGGSGVMTGTSMAAPHVAGQAAILAS 363
>sp|P35211|ORYZ_ASPFL Alkaline protease 1 OS=Aspergillus flavus
OX=5059 GN=alp1 PE=1 SV=1
Length=403
Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats.
Identities = 42/332 (13%), Positives = 106/332 (32%), Gaps = 39/332 (12%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
+++++ +V +E+ D+ + P W L ++ + G
Sbjct 101 AQIRQSDEVAAVEEDQVW--HLFDLTTQSDAP-----WGLGSISHKGQPSTDYIYDTNGG 153
Query 145 HGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA 204
G ++D GI +H + G ++ HGT +G +
Sbjct 154 EGTYAYVVDIGINVDHEEFEGRASLAYH----------AAGGQHVDGVGHGTHVSGTI-- 201
Query 205 VANNGVCGVGVAYNARIGGVRMLDG-EVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTV 263
G GVA A + V++ G + ++ N I + +
Sbjct 202 ----GGKTYGVAKKANLLSVKVFVGESSSTSIILDGFNWAANDIVSKKRTGKAAINMSLG 257
Query 264 DGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQF 323
G ++ +A ++ G + + A+GN + + ++ ++++
Sbjct 258 GGYSKAFNDAVENAFNE-----GVLSIVAAGNENTDASRTSPASAPDAF---TVAAINVN 309
Query 324 GNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC-TESHTGTSASAPLAAGIIALTL 382
++S S I++ + T + +GTS + P G+ +
Sbjct 310 NTRAYFSNYGSVVDIFAPGQ------NILSAWIGSNTATNTISGTSMATPHIVGLSIYLM 363
Query 383 EANKNLTWRDMQHLVVQTSKPAHLNANDWATN 414
+ + + + + + ++ + N
Sbjct 364 SLEVLSSPKAVSDRIKELATRGVVSNVAGSPN 395
>sp|D4B194|SUB5_ARTBC Subtilisin-like protease 5 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331 GN=SUB5
PE=3 SV=1
Length=396
Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats.
Identities = 61/348 (18%), Positives = 122/348 (35%), Gaps = 65/348 (19%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ +P+V ++E ++ V Q+ P W LS ++ R + G G
Sbjct 98 ISNDPKVAFVEPDAI--ISQHVVVQQRKAP-----WGLSRLSNRRGGRNYVFD-SSAGSG 149
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D G++ H + G G++ N + HGT AG +A
Sbjct 150 VWAYVVDSGVDVRHSEFQGRAVWGSNLVDNKN----------SDGTGHGTHVAGTIAGKT 199
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIH----------IYSASWGP 256
G+A NA++ V++L+ E G+N + H + + S G
Sbjct 200 ------YGIAKNAKVVAVKVLNSEGKGPTSGIIAGINWSIRHARKHGMLQKSVLNMSLGG 253
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
A + G ++GN ++ + N + + +
Sbjct 254 TY-------------SAGLNHATAQAIKAGMFVSVSAGN---DNINSNGNSPASERSVCT 297
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAG 376
I+++T+ +S + Y+ G + + +++ +GTS +AP AAG
Sbjct 298 IAASTENDGKASFSNWGPA--VDLYAPG-----HNILSARPGGGSQTMSGTSMAAPHAAG 350
Query 377 IIALTLEA------NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ A + L + + ++ P + NG GR
Sbjct 351 VAAYLIAKEGIPGNRACLRLKQLSQPTIR--NPGPDTTSRLLYNGSGR 396
>sp|E4UY04|SUB12_ARTGP Subtilisin-like protease 12 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB12
PE=3 SV=1
Length=397
Score = 118 bits (296), Expect = 2e-27, Method: Composition-based stats.
Identities = 61/342 (18%), Positives = 121/342 (35%), Gaps = 59/342 (17%)
Query 75 RSLSPHRPRHS--RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDL 132
++ S + + + V+++E R++ T + W L+ ++ +
Sbjct 84 QAYSGSFDKDTIQEILNHENVEFVEPN-------REMKAASTIKQENITWGLARISHMEN 136
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
+ G + +D GI+ + D G G +N D + ++
Sbjct 137 FSHDYVSTYGEGENLTFYGIDSGIDIHQSDFTGRARWG----INVAD------HIDIDCI 186
Query 193 RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD----GEVTDAVEARSLGLNPNHIH 248
HGT AG VA + G+ A I V++LD G+ T + + +N
Sbjct 187 GHGTHTAGTVAGQS------FGILKKASIVSVKVLDCYGHGDTTKYINGLNWAINDAKKR 240
Query 249 ------IYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDS 302
+ + S G G +R EA R G A+GN +
Sbjct 241 GLLGKSVMNISLGT--------GRSRAVNEATVRA-----QEAGIFISVAAGNNAINAEF 287
Query 303 CNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTE 362
+ ++ +++++T+ ++S + L ++ G + + L T
Sbjct 288 LSP---GSAPELCTVAASTRNDTRAYFSNYGA--LIDLFAPGEY-----IRSTLPHNRTG 337
Query 363 SHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPA 404
+GTS +AP GI L + A L + + + + PA
Sbjct 338 IMSGTSMAAPHVCGIGGLIMAAE-GLAPEQVCRRLKELANPA 378
>sp|Q1DFT5|POPC_MYXXD Subtilisin-like protease PopC OS=Myxococcus
xanthus (strain DK1622) OX=246197 GN=popC PE=1 SV=1
Length=475
Score = 119 bits (297), Expect = 4e-27, Method: Composition-based stats.
Identities = 72/359 (20%), Positives = 123/359 (34%), Gaps = 31/359 (9%)
Query 80 HRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRD-LNVKAAW 138
H + +R + E +++ V V P+ L+ D V A
Sbjct 128 HTEKEARGELERDFEFI-PDVVPLSFPGPVSAGQPGPRNRGMSSLAEREWPDECGVPLAH 186
Query 139 AQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP-DPQPRYTQMNDNRHGTR 197
AQG G G+++ ILD G++ +HP+ A + P +P + + HGT
Sbjct 187 AQGIRGAGVMLGILDTGVDADHPEHAARVIQFRYVSLFPNSPHNPARDIRGFDPDGHGTH 246
Query 198 CAGEVAAVANNGVCGVGVAYNARIGGVRMLD--------GEVTDAVEAR----SLGLNPN 245
G A V GVA + +++ G V +E S N
Sbjct 247 VCGIAAGV------HHGVAPEVDLYVASVIESETIRTSLGRVAAGMEWLLHQFSRPENST 300
Query 246 HIHIYSASWG-PEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCN 304
+ + S G P + + + + + V A+GN G +
Sbjct 301 RPAVVNLSLGFPLMPPPGISEADYNLNLRALQTMIRRLLDSNVLPVVAAGNSGPDTVGYP 360
Query 305 CDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL---RQKCT 361
+ S L++ + NV +S + + +T+ Q
Sbjct 361 A-AFPES---LAVGAVDFERNVATFSASGTVGRRVVPDIMGYGVNVYSSTERRCNNQAFY 416
Query 362 ESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
E +GTS +AP AGI AL +LT +++ L++ S L + G G V
Sbjct 417 ERMSGTSMAAPYVAGIAALYRCRAPDLTALEVRDLIL--SNAVKLPRSGTHKTGKGLAV 473
>sp|Q8J0D8|SUB2_ARTOT Subtilisin-like protease 2 OS=Arthroderma
otae OX=63405 GN=SUB2 PE=3 SV=2
Length=424
Score = 117 bits (293), Expect = 7e-27, Method: Composition-based stats.
Identities = 72/420 (17%), Positives = 133/420 (32%), Gaps = 63/420 (15%)
Query 22 ADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHR 81
A + + V + G A A K ++ Q D + GV + +
Sbjct 26 LRAGPSDIVPGQYIVTLKEGLASAQIREHKKWVSSVHQANLDSFAAGASGVETVGIMKNF 85
Query 82 PRHSR--------------LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGV 127
H+ L+R P V+ + + VY T + +W L +
Sbjct 86 HIHNLNMYSGGFDDKTAEDLRRSPDVKSVHPD-------QHVYLAKTVTQPQARWGLGYM 138
Query 128 TQRDLNVK------AAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPD 181
+ + + V G G+ +LD GI +H + G +
Sbjct 139 SSKGMPVPLHSTLVDYLYDDKAGEGVWAYVLDTGINVDHIEFEDRGILG---------HN 189
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD-GEVTDAVEARSL 240
P ++ HGT AG +A GVA A + + D G T +
Sbjct 190 AIPNKPHTDEFEHGTYVAGIIAGKT------YGVAKKANVVSAKAFDTGSSTYNYILETY 243
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
+I + + ++ A+ F + G V A+GN G++
Sbjct 244 DWIVKNITDSN-----RKNKAVINLSISGAKYQPFDDAVENAFKAGITAVVAAGNDGKDA 298
Query 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGN---QNEKQIVTTDLR 357
+ N+I ++ + P LA+ Y + I +
Sbjct 299 KNNTPASSPNAI---TVGAVRWENTRPS--------LASNYGKIVDIWAPGELIKSCWKG 347
Query 358 QKC-TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGV 416
T + +GTSA++P AG++A + + + V+ + P + + N V
Sbjct 348 GNNATSTQSGTSAASPHVAGLVAYLMSLENLPSPSAVTARVLNLTIPNLVKDAKDSPNRV 407
>sp|C5P906|SUB2B_COCP7 Subtilisin-like protease CPC735_003880
OS=Coccidioides posadasii (strain C735) OX=222929 GN=CPC735_003880
PE=3 SV=1
Length=410
Score = 116 bits (291), Expect = 1e-26, Method: Composition-based stats.
Identities = 61/326 (19%), Positives = 106/326 (33%), Gaps = 38/326 (12%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
++R P V+ + R VY T + + L ++ + + G G
Sbjct 100 IRRNPYVKSVTPD-------RKVYLADTVVQENAGYNLGHMSSKGRHSFTYRYDSTAGEG 152
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
I +LD GI +H + G D G + N + ++ HG+ AG +AA
Sbjct 153 IWAYVLDTGINVDHIEFEGRADSGYNAIKN---------VSNTDNFGHGSFTAGIIAAKT 203
Query 207 NNGVCGVGVAYNARIGGVRMLD-GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDG 265
GVA A + + D G T + + + + V+
Sbjct 204 ------YGVAKKATVISAKAFDTGSSTYDYIFDAYNWV-----VKNITDSGRQKKSVVNM 252
Query 266 PARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGN 325
A+ F G V A+GN R+ + N+I +++S
Sbjct 253 SISSAKYQPFDDAVDNAFEAGITTVVAAGNDQRDASNNTPASAANAI---TVASIRFDNG 309
Query 326 VPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC-TESHTGTSASAPLAAGIIALTLEA 384
+S S +IV+ + T GTS S+P AG++A +
Sbjct 310 RSLFSNYGSVVDIFAPGE------RIVSCWIGGNNATRKADGTSVSSPHVAGLVAYLMAI 363
Query 385 NKNLTWRDMQHLVVQTSKPAHLNAND 410
+ V+ S P +
Sbjct 364 EDLPDPAAVTKRVLDLSIPDLVRDPG 389
>sp|E4V2L6|SUB5_ARTGP Subtilisin-like protease 5 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB5
PE=3 SV=1
Length=396
Score = 115 bits (287), Expect = 3e-26, Method: Composition-based stats.
Identities = 64/385 (17%), Positives = 129/385 (34%), Gaps = 84/385 (22%)
Query 69 HRGVTKRSLSPHRPRHS-------------------RLQREPQVQWLEQQVAKRRTKRDV 109
H VT+R L+ + + + +P+V ++E ++
Sbjct 61 HHNVTRRGLNGEGVKETYDFDNVRGYSGIFDKDTIKDISNDPKVAFVEPDAIIKQHVFVQ 120
Query 110 YQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDP 169
++ W LS ++ R + G+G+ ++D G++ +H + G
Sbjct 121 QRKAP-------WGLSRLSNRRGGRNYVFDST-AGNGVWAYVVDSGVDIHHSEFQGRAIW 172
Query 170 GASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG 229
G++ N + HGT AG +A G+A A+I V++LD
Sbjct 173 GSNLVDNKN----------SDGTGHGTHVAGTIAGKT------YGIAKKAKIIAVKVLDS 216
Query 230 EVTDAVEARSLGLNPNHIH----------IYSASWGPEDDGKTVDGPARLAEEAFFRGVS 279
E G+N + H + + S G AR +
Sbjct 217 EGKGPTSGIIAGINWSIKHARQHGKLQKSVLNMSLGGSYSAGLNHVTARAIK-------- 268
Query 280 QGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLAT 339
G ++GN ++ + + +I+++T+ +S +
Sbjct 269 -----AGMFVSVSAGNDNINSNNNSP---ASERSVCTIAASTENDGKASFSNWGPA--VD 318
Query 340 TYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA------NKNLTWRDM 393
Y+ G + + +++ +GTS +AP AAG+ A + L + +
Sbjct 319 LYAPG-----HNILSARPGGGSQTMSGTSMAAPHAAGVAAYLIAKEGIPGDRVCLRLKQL 373
Query 394 QHLVVQTSKPAHLNANDWATNGVGR 418
++ P + NG GR
Sbjct 374 SRPTIR--NPGPDTTSRLLYNGSGR 396
>sp|C5FZ39|SUB11_ARTOC Subtilisin-like protease 11 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB11
PE=3 SV=1
Length=400
Score = 114 bits (286), Expect = 4e-26, Method: Composition-based stats.
Identities = 71/396 (18%), Positives = 125/396 (32%), Gaps = 59/396 (15%)
Query 33 TWAVRIPGGPAVANSVARKH-GFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREP 91
TWA + G +V+ A GF Y + G S S H+ +
Sbjct 54 TWATDLH-GESVSRRGADGLNGFK---------YSYKINGWHAYSGSFHQETLDEILNND 103
Query 92 QVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSI 151
+V ++E + ++ W L V+ R + G GI
Sbjct 104 KVDFVEHDRYVYISGFVTQKDAPS------WGLGRVSHRHNGTRDYVYDERAGKGITFYG 157
Query 152 LDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVC 211
+D GI+ +HPD G G + +D D Q T
Sbjct 158 VDTGIDIHHPDFGGRAVWGTNVVNGTKDNDRQGHGTHTAATA---------------TGT 202
Query 212 GVGVAYNARIGGVRMLDGEVTD----AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPA 267
G+A NA + V+ L+ ++A + + + G
Sbjct 203 KYGLAKNANVVAVKALNDYGAGLWSNIMKALEWCVE--DATKKNIIGKAVLNLSISGGKV 260
Query 268 RLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVP 327
A +A + G A+GN ++ + + ++ ++ T +
Sbjct 261 VAANQAVTKTAK-----AGIFVSVAAGNDNQDATNKSP---ASAEGVCCAAATTIRDDKA 312
Query 328 WYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKN 387
+S S G +T+ T +GTS +AP G+ A TL A+K
Sbjct 313 KFSNYGSVVKIYAPGQG-------ITSATPNNSTGVMSGTSMAAPHVGGVGA-TLMASKG 364
Query 388 LTWRDMQHLVVQTS-----KPAHLNANDWATNGVGR 418
+ D+ +++ + P N NG G+
Sbjct 365 IAPADLCAELIKVASGPVQNPGSSTTNKLLYNGSGQ 400
>sp|C5FX37|SUB10_ARTOC Subtilisin-like protease 10 OS=Arthroderma
otae (strain ATCC MYA-4605 / CBS 113480) OX=554155 GN=SUB10
PE=3 SV=1
Length=401
Score = 109 bits (273), Expect = 2e-24, Method: Composition-based stats.
Identities = 57/307 (19%), Positives = 95/307 (31%), Gaps = 36/307 (12%)
Query 80 HRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWA 139
R L + QV ++E + + + P W L ++ +
Sbjct 91 DRATLDDLLKNEQVDYIEPDRM--ASAQGWTTQGNAPS----WGLGRISHQQRGNTDYVF 144
Query 140 QGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCA 199
G GI + +D GI+ H + G GA+F N ++ HGT A
Sbjct 145 DSTAGRGITIYGVDSGIDILHAEFGGRATWGANFFNNIN----------TDEFGHGTHTA 194
Query 200 GEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLG--LNPNHIHIYSASWGPE 257
GVA N I V++L + + G N
Sbjct 195 ATFGGTN------YGVAKNVNIVAVKVLGDQGQGPWSSIIDGLQWAVNDAREKGILGKAI 248
Query 258 DDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSI 317
+ +R A+ A + G +FV A+ G SI I
Sbjct 249 INFSVGGPSSRAADNALTAAHNAG------VFVSAAAGNDGADALNYTPGTARSICV--I 300
Query 318 SSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGI 377
+ + ++ +S T + + L Q TGTS +AP AG
Sbjct 301 GNINENDYR--FTGNGASNWGTRIDLWAPGTD--ILSALPQGRYGPMTGTSMAAPHVAGS 356
Query 378 IALTLEA 384
+A+ + +
Sbjct 357 VAILMAS 363
>sp|D4CZ60|SUB11_TRIVH Subtilisin-like protease 11 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB11 PE=3 SV=1
Length=400
Score = 109 bits (272), Expect = 3e-24, Method: Composition-based stats.
Identities = 54/342 (16%), Positives = 99/342 (29%), Gaps = 49/342 (14%)
Query 50 RKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSR--LQREPQVQWLEQQVAKRRTKR 107
K G NLG + H + S + + +V ++E +
Sbjct 65 AKRGAENLG----GFKHSYKINGWHA-YSGSFDSETLASILDNDKVDFVEHDRHVYISGF 119
Query 108 DVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNY 167
++ W L V+ R + G GI +D GI+ +HPD G
Sbjct 120 VTQKDAPS------WGLGRVSHRMNGTRDYVYDESAGSGITFYGVDTGIDIHHPDFGGRA 173
Query 168 DPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
G + + +D D T G+A A + V+ L
Sbjct 174 VWGINVVNDTKDNDRHGHGTHTAATA---------------AGTKYGLAKKANVVAVKAL 218
Query 228 DGEVTD----AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRG 283
+ ++A + N + G A +A
Sbjct 219 NDYGAGLWSNIMKALEWCV--NDAREKKILGKAVLNLSISGGKVVAANQAITNAAK---- 272
Query 284 GLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSS 343
G A+GN ++ + + ++ ++ T + +S S
Sbjct 273 -AGIFVSVAAGNDNQDATNKSP---ASAENVCCAAATTIRDDKAKFSNYGSVVKLYAPGQ 328
Query 344 GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEAN 385
G +T+ T +GTS +AP G+ A + +
Sbjct 329 G-------ITSATPNNQTGVMSGTSMAAPHVGGVGATLMASK 363
>sp|D4APE3|SUB11_ARTBC Subtilisin-like protease 11 OS=Arthroderma
benhamiae (strain ATCC MYA-4681 / CBS 112371) OX=663331
GN=SUB11 PE=3 SV=1
Length=400
Score = 109 bits (271), Expect = 4e-24, Method: Composition-based stats.
Identities = 63/380 (17%), Positives = 113/380 (30%), Gaps = 55/380 (14%)
Query 50 RKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSR--LQREPQVQWLEQQVAKRRTKR 107
K G NLG + H + S + + +V ++E +
Sbjct 65 AKRGAENLG----GFKHSYKINGWHA-YSGSFDSETLASILDNDKVDFVEHDRHVYISGF 119
Query 108 DVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNY 167
++ W L V+ R + G GI +D GI+ +HPD G
Sbjct 120 VTQKDAPS------WGLGRVSHRMNGTRDYVYDESAGSGITFYGVDTGIDIHHPDFGGRA 173
Query 168 DPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML 227
G + +D D T G+A A + V+ L
Sbjct 174 VWGINVVNGTKDNDRHGHGTHTAATA---------------AGTKYGLAKKANVVAVKAL 218
Query 228 DGEVTD----AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRG 283
+ ++A + N + G A +A
Sbjct 219 NDYGAGLWSNIMKALEWCV--NDAREKKILGKAVLNLSISGGKVVAANQAITNAAK---- 272
Query 284 GLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSS 343
G A+GN ++ + + ++ ++ T + +S S
Sbjct 273 -AGIFVSVAAGNDNQDATNKSP---ASAENVCCAAATTIRDDKAKFSNYGSVVKLYAPGQ 328
Query 344 GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTS-- 401
G +T+ T +GTS +AP G+ A TL A+K + + +++ +
Sbjct 329 G-------ITSATPNNQTGVMSGTSMAAPHIGGVGA-TLMASKGIAPSAVCAELIKMASG 380
Query 402 ---KPAHLNANDWATNGVGR 418
P N NG G+
Sbjct 381 PVLNPGANTTNKLLYNGSGK 400
>sp|P72186|PLS_PYRFU Pyrolysin OS=Pyrococcus furiosus (strain
ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) OX=186497 GN=pls PE=1
SV=2
Length=1398
Score = 112 bits (281), Expect = 4e-24, Method: Composition-based stats.
Identities = 60/376 (16%), Positives = 121/376 (32%), Gaps = 102/376 (27%)
Query 141 GYTGHGIVVSILDDGIEKNHPD---------------LAGNYDPGASFDVNDQDPDPQPR 185
TG+G ++ +D ++ + D + Y P ++ + + DP+ +
Sbjct 298 NSTGNGYDIAYVDTDLDYDFTDEVPLGQYNVTYDVAVFSYYYGPL-NYVLAEIDPNGEYA 356
Query 186 YTQMNDNRHGTRCAGEVAAVANNGVC-----------------------------GVGVA 216
+ + HGT AG VA +N GVA
Sbjct 357 VFGWDGHGHGTHVAGTVAGYDSNNDAWDWLSMYSGEWEVFSRLYGWDYTNVTTDTVQGVA 416
Query 217 YNARIGGVRML--DGEVT--DAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEE 272
A+I +R+L DG + D +E + + + S S G P +A
Sbjct 417 PGAQIMAIRVLRSDGRGSMWDIIEGMTYAA-THGADVISMSLGGNAPYLDGTDPESVA-- 473
Query 273 AFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTL---------------SI 317
V + G +FV A+GN G + G T+ ++
Sbjct 474 -----VDELTEKYGVVFVIAAGNEGPGINIVGSPGVATKAITVGAAAVPINVGVYVSQAL 528
Query 318 SSATQFG--NVPWYSEACSSTLATTYSSGNQN-EKQIVTTDLRQKCT--------ESHTG 366
+G P Y+ + ++ + + +V + + +G
Sbjct 529 GYPDYYGFYYFPAYTNVRIAFFSSRGPRIDGEIKPNVVAPGYGIYSSLPMWIGGADFMSG 588
Query 367 TSASAPLAAGIIALTLEA--------NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
TS + P +G++AL + N ++ ++ ++ + G+
Sbjct 589 TSMATPHVSGVVALLISGAKAEGIYYNPDI----IKKVLESGATWLE------GDPYTGQ 638
Query 419 KVSH-SYGYGLLDAGA 433
K + G+GL++
Sbjct 639 KYTELDQGHGLVNVTK 654
Score = 44.8 bits (104), Expect = 0.004, Method: Composition-based stats.
Identities = 62/364 (17%), Positives = 110/364 (30%), Gaps = 73/364 (20%)
Query 92 QVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSI 151
+V+ V K ++ EP + W ++ ++ GY G G+VV++
Sbjct 127 EVKLSPPIVEKDVKTKEPSLEPK--MYNSTWVINA-------LQFIQEFGYDGSGVVVAV 177
Query 152 LDDGIEKNHPDLAGNYDPGASF----DVNDQDPDPQPRYTQMNDNRHGT-------RCAG 200
LD G++ NHP L+ D D D+ N GT + A
Sbjct 178 LDTGVDPNHPFLSITPDGRRKIIEWKDFTDEGFVDTSFSFSKVVN--GTLIINTTFQVAS 235
Query 201 -----------------------EVAAVAN-NGVCGVGVAYNARIGGVRMLDGEVTDAVE 236
+ + + NG+ G+ R + DG+ D
Sbjct 236 GLTLNESTGLMEYVVKTVYVSNVTIGNITSANGIYHFGLLPE-RYFDLNF-DGDQEDFYP 293
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI-FVWASGN 295
+ N I + D L + V+ G + +V A +
Sbjct 294 VLLVNSTGNGYDIAYVDTDLDYD---FTDEVPLGQYNVTYDVAVFSYYYGPLNYVLAEID 350
Query 296 GGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTD 355
E+ DG+ + + + N W + S +S + VTTD
Sbjct 351 PNGEYAVFGWDGHGHGTHVAGTVAGYDSNNDAWDWLSMYSGEWEVFSRLYGWDYTNVTTD 410
Query 356 L--------------------RQKCTESHTGTSASAPLAAGIIALTLEAN-KNLTWRDMQ 394
R + G + +A A +I+++L N L D +
Sbjct 411 TVQGVAPGAQIMAIRVLRSDGRGSMWDIIEGMTYAATHGADVISMSLGGNAPYLDGTDPE 470
Query 395 HLVV 398
+ V
Sbjct 471 SVAV 474
>sp|Q0WUG6|SBT61_ARATH Subtilisin-like protease SBT6.1 OS=Arabidopsis
thaliana OX=3702 GN=SBT6.1 PE=1 SV=1
Length=1038
Score = 112 bits (280), Expect = 5e-24, Method: Composition-based stats.
Identities = 67/303 (22%), Positives = 118/303 (39%), Gaps = 48/303 (16%)
Query 133 NVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN 192
W +GYTG + ++I D GI +HP ++ +NDN
Sbjct 192 GADHLWKKGYTGAKVKMAIFDTGIRADHPHFR-KIKERTNW----------TNEDTLNDN 240
Query 193 -RHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRML-DGEVTDA---VEARSLGLNPNHI 247
HGT AG +A N C +G A + I R+ D +V+ ++A + + + +
Sbjct 241 LGHGTFVAGVIAG--RNPEC-LGFASDTEIYAFRVFTDAQVSYTSWFLDAFNYAIATD-M 296
Query 248 HIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDG 307
+ + S G D +D P E+ + S I V A GN G + + N
Sbjct 297 DVLNLSIGGPDY---LDLP--FVEKVWEITASN------IIMVSAIGNDGPLYGTLNNP- 344
Query 308 YTNSIYTLSISSATQFGNVPWYSEACSST--LATTYSSGNQN----EKQIVTTDLRQKCT 361
+ + + ++ +S ST L Y + + I+ + + C
Sbjct 345 -ADQSDVIGVGGIDNDDHIASFSSRGMSTWELPHGYGRVKPDVVAYGRDIMGSKISTGC- 402
Query 362 ESHTGTSASAPLAAGIIALTLEANKN------LTWRDMQHLVVQTSKPAHLNANDWATNG 415
+S +GTS ++P+ AGI+ L + L M+ +V+ + A L+ + G
Sbjct 403 KSLSGTSVASPVVAGIVCLLVSVIPEARRKDLLNPASMKQALVEGA--AKLSGPNMYEQG 460
Query 416 VGR 418
GR
Sbjct 461 AGR 463
>sp|E4V5C5|SUB11_ARTGP Subtilisin-like protease 11 OS=Arthroderma
gypseum (strain ATCC MYA-4604 / CBS 118893) OX=535722 GN=SUB11
PE=3 SV=1
Length=400
Score = 108 bits (269), Expect = 8e-24, Method: Composition-based stats.
Identities = 63/369 (17%), Positives = 108/369 (29%), Gaps = 51/369 (14%)
Query 61 FGDYYHFWHRGVTKRSLSPHRPRHSR--LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKF 118
+ H + S + + QV ++E R D D
Sbjct 72 LDGFKHSYKINGWHA-YSGSFDSETLASILDNDQVDFVEHD---RYVYIDGLVTQKD--- 124
Query 119 PQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ 178
W L V+ R + G GI +D GI+ HPD G G +
Sbjct 125 APSWGLGRVSHRMNGTRDYVYDETAGSGITFYGVDTGIDIRHPDFGGRAVWGTNVVSGTG 184
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTD----A 234
D D T G+A A + V+ L+
Sbjct 185 DNDRHGHGTHTAATA---------------TGTKYGLAKKANVVAVKALNDHGAGLWSNI 229
Query 235 VEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASG 294
++A + + +A + G A +A G A+G
Sbjct 230 MKALEWCV--DDARKKNALGKAVLNLSISGGKVVAANQAITNAA-----NAGIFVSVAAG 282
Query 295 NGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTT 354
N ++ + + ++ +++T S S G +T+
Sbjct 283 NDNQDATNKSP---ASAENVCCAAASTIRDEKASISNYGSVVKLYAPGQG-------ITS 332
Query 355 DLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTS-----KPAHLNAN 409
T TGTS +AP G+ A TL A+K++ + +++ + P N
Sbjct 333 ATPNNSTGVMTGTSMAAPHVGGVGA-TLMASKHIAPSAVCAELIKMATGAVRNPGANTTN 391
Query 410 DWATNGVGR 418
NG G+
Sbjct 392 KLLYNGSGQ 400
>sp|Q14703|MBTP1_HUMAN Membrane-bound transcription factor site-1
protease OS=Homo sapiens OX=9606 GN=MBTPS1 PE=1 SV=1
Length=1052
Score = 109 bits (273), Expect = 3e-23, Method: Composition-based stats.
Identities = 74/424 (17%), Positives = 141/424 (33%), Gaps = 89/424 (21%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDP----KFPQQWYLSGVTQRD----------- 131
L+ P ++ + Q R+ + +PT P ++ Q+W S +R
Sbjct 117 LEDHPNIKRVTPQRKVFRSLKYAESDPTVPCNETRWSQKWQSSRPLRRASLSLGSGFWHA 176
Query 132 --------------------LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGA 171
L W GYTG + V++ D G+ + HP N
Sbjct 177 TGRHSSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSEKHPHFK-NVKERT 235
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEV 231
++ T + HGT AG +A++ C G A +A + R+
Sbjct 236 NW---------TNERTLDDGLGHGTFVAGVIASMRE---CQ-GFAPDAELHIFRVFTNNQ 282
Query 232 TDAVEARSLGLNP---NHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
N I + + S G D +D P ++ + + I
Sbjct 283 VSYTSWFLDAFNYAILKKIDVLNLSIGGPDF---MDHP--FVDKVWELTANN------VI 331
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNE 348
V A GN G + + N + + + + N+ +S +T + +
Sbjct 332 MVSAIGNDGPLYGTLNNP--ADQMDVIGVGGIDFEDNIARFSSRGMTT-WELPGGYGRMK 388
Query 349 KQIVT-------TDLRQKCTESHTGTSASAPLAAGIIALT---LEANKNLTWRDMQHLVV 398
IVT + ++ C + +GTS ++P+ AG + L ++ + + M+ ++
Sbjct 389 PDIVTYGAGVRGSGVKGGC-RALSGTSVASPVVAGAVTLLVSTVQKRELVNPASMKQALI 447
Query 399 QTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEP 458
+++ GV G+G LD + ++ A ID+ P
Sbjct 448 ASARRLP---------GVNMF---EQGHGKLDLLRAYQILNSYKPQASLSPSYIDLTECP 495
Query 459 KDIG 462
Sbjct 496 YMWP 499
>sp|Q9Z2A8|MBTP1_CRIGR Membrane-bound transcription factor site-1
protease OS=Cricetulus griseus OX=10029 GN=MBTPS1 PE=1 SV=2
Length=1052
Score = 108 bits (270), Expect = 7e-23, Method: Composition-based stats.
Identities = 70/424 (17%), Positives = 139/424 (33%), Gaps = 89/424 (21%)
Query 87 LQREPQVQWLEQQV----AKRRTKRDVYQEPTDPKFPQQWYLSGVTQRD----------- 131
L+ P ++ + Q + + + D + ++ Q+W S +R
Sbjct 117 LEDHPNIKRVTPQRKVFRSLKFAESDPIVPCNETRWSQKWQSSRPLRRASLSLGSGFWHA 176
Query 132 --------------------LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGA 171
L W GYTG + V++ D G+ + HP N
Sbjct 177 TGRHSSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSEKHPHFK-NVKERT 235
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEV 231
++ T + HGT AG +A++ C G A +A + R+
Sbjct 236 NW---------TNERTLDDGLGHGTFVAGVIASMRE---CQ-GFAPDAELHIFRVFTNNQ 282
Query 232 TDAVEARSLGLNP---NHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
N I + + S G D +D P ++ + + I
Sbjct 283 VSYTSWFLDAFNYAILKKIDVLNLSIGGPDF---MDHP--FVDKVWELTANN------VI 331
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNE 348
V A GN G + + N + + + + N+ +S +T + +
Sbjct 332 MVSAIGNDGPLYGTLNNP--ADQMDVIGVGGIDFEDNIARFSSRGMTT-WELPGGYGRVK 388
Query 349 KQIVT-------TDLRQKCTESHTGTSASAPLAAGIIALT---LEANKNLTWRDMQHLVV 398
IVT + ++ C + +GTS ++P+ AG + L ++ + + ++ ++
Sbjct 389 PDIVTYGAGVRGSGVKGGC-RALSGTSVASPVVAGAVTLLVSTVQKRELVNPASVKQALI 447
Query 399 QTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEP 458
+++ GV G+G LD + ++ A ID+ P
Sbjct 448 ASARRLP---------GVNMF---EQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECP 495
Query 459 KDIG 462
Sbjct 496 YMWP 499
>sp|Q9WTZ3|MBTP1_RAT Membrane-bound transcription factor site-1
protease OS=Rattus norvegicus OX=10116 GN=Mbtps1 PE=1 SV=2
Length=1052
Score = 108 bits (270), Expect = 7e-23, Method: Composition-based stats.
Identities = 70/424 (17%), Positives = 139/424 (33%), Gaps = 89/424 (21%)
Query 87 LQREPQVQWLEQQV----AKRRTKRDVYQEPTDPKFPQQWYLSGVTQRD----------- 131
L+ P ++ + Q + + + D + ++ Q+W S +R
Sbjct 117 LEDHPNIKRVTPQRKVFRSLKFAESDPIVPCNETRWSQKWQSSRPLKRASLSLGSGFWHA 176
Query 132 --------------------LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGA 171
L W GYTG + V++ D G+ + HP N
Sbjct 177 TGRHSSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSEKHPHFK-NVKERT 235
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEV 231
++ T + HGT AG +A++ C G A +A + R+
Sbjct 236 NW---------TNERTLDDGLGHGTFVAGVIASMRE---CQ-GFAPDAELHIFRVFTNNQ 282
Query 232 TDAVEARSLGLNP---NHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
N I + + S G D +D P ++ + + I
Sbjct 283 VSYTSWFLDAFNYAILKKIDVLNLSIGGPDF---MDHP--FVDKVWELTANN------VI 331
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNE 348
V A GN G + + N + + + + N+ +S +T + +
Sbjct 332 MVSAIGNDGPLYGTLNNP--ADQMDVIGVGGIDFEDNIARFSSRGMTT-WELPGGYGRVK 388
Query 349 KQIVT-------TDLRQKCTESHTGTSASAPLAAGIIALT---LEANKNLTWRDMQHLVV 398
IVT + ++ C + +GTS ++P+ AG + L ++ + + ++ ++
Sbjct 389 PDIVTYGAGVRGSGVKGGC-RALSGTSVASPVVAGAVTLLVSTVQKRELVNPASVKQALI 447
Query 399 QTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEP 458
+++ GV G+G LD + ++ A ID+ P
Sbjct 448 ASARRLP---------GVNMF---EQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECP 495
Query 459 KDIG 462
Sbjct 496 YMWP 499
>sp|P59996|PCSK9_RAT Proprotein convertase subtilisin/kexin type
9 OS=Rattus norvegicus OX=10116 GN=Pcsk9 PE=1 SV=1
Length=691
Score = 107 bits (267), Expect = 1e-22, Method: Composition-based stats.
Identities = 64/376 (17%), Positives = 124/376 (33%), Gaps = 52/376 (14%)
Query 42 PAVANSV---ARKHGFLN-LGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLE 97
A+ + A + G++ + +F D + + ++ L P V+++E
Sbjct 91 EQTAHRLQTWAARRGYVIKVLHVFYDLFPGFLVKMSSDLLGLALKL-------PHVEYIE 143
Query 98 QQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGY------TGHGIVVSI 151
+ + + P W L + AW Q + V +
Sbjct 144 ED--------SLVFAQSIP-----WNLERI-------IPAWQQTEEDSSPDGSSQVEVYL 183
Query 152 LDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVC 211
LD I+ H ++ G F+ ++ + + HGT AG V+
Sbjct 184 LDTSIQSGHREIEGRVTI-TDFNSVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD----- 237
Query 212 GVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAE 271
GVA + +R+L+ + V +GL GP V P
Sbjct 238 -AGVAKGTSLHSLRVLNCQGKGTVSGTLIGLEFIRKSQLIQPSGPL----VVLLPLAGGY 292
Query 272 EAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSE 331
Q G + V A+GN D+C ++ +++ +
Sbjct 293 SRILNTACQRLARTGVVLVAAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQPVTLGT 349
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWR 391
++ + ++D C S +GTS +A AGI+A+ L + LT
Sbjct 350 LGTNFGRCVDLFAPGKDIIGASSDC-STCYMSQSGTSQAAAHVAGIVAMMLNRDPALTLA 408
Query 392 DMQHLVVQTSKPAHLN 407
+++ ++ S +N
Sbjct 409 ELRQRLILFSTKDVIN 424
>sp|Q9WTZ2|MBTP1_MOUSE Membrane-bound transcription factor site-1
protease OS=Mus musculus OX=10090 GN=Mbtps1 PE=1 SV=1
Length=1052
Score = 107 bits (267), Expect = 2e-22, Method: Composition-based stats.
Identities = 70/424 (17%), Positives = 139/424 (33%), Gaps = 89/424 (21%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEP----TDPKFPQQWYLSGVTQRD----------- 131
L+ P ++ + Q R+ + P + ++ Q+W S +R
Sbjct 117 LEDHPNIKRVTPQRKVFRSLKFAESNPIVPCNETRWSQKWQSSRPLKRASLSLGSGFWHA 176
Query 132 --------------------LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGA 171
L W GYTG + V++ D G+ + HP N
Sbjct 177 TGRHSSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSEKHPHFK-NVKERT 235
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEV 231
++ T + HGT AG +A++ C G A +A + R+
Sbjct 236 NW---------TNERTLDDGLGHGTFVAGVIASMRE---CQ-GFAPDAELHIFRVFTNNQ 282
Query 232 TDAVEARSLGLNP---NHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
N + + + S G D +D P ++ + + I
Sbjct 283 VSYTSWFLDAFNYAILKKMDVLNLSIGGPDF---MDHP--FVDKVWELTANN------VI 331
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNE 348
V A GN G + + N + + + + N+ +S +T + +
Sbjct 332 MVSAIGNDGPLYGTLNNP--ADQMDVIGVGGIDFEDNIARFSSRGMTT-WELPGGYGRVK 388
Query 349 KQIVT-------TDLRQKCTESHTGTSASAPLAAGIIALT---LEANKNLTWRDMQHLVV 398
IVT + ++ C + +GTS ++P+ AG + L ++ + + ++ ++
Sbjct 389 PDIVTYGAGVRGSGVKGGC-RALSGTSVASPVVAGAVTLLVSTVQKRELVNPASVKQALI 447
Query 399 QTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEP 458
+++ GV G+G LD + ++ A ID+ P
Sbjct 448 ASARRLP---------GVNMF---EQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECP 495
Query 459 KDIG 462
Sbjct 496 YMWP 499
>sp|Q80W65|PCSK9_MOUSE Proprotein convertase subtilisin/kexin
type 9 OS=Mus musculus OX=10090 GN=Pcsk9 PE=1 SV=2
Length=694
Score = 106 bits (265), Expect = 2e-22, Method: Composition-based stats.
Identities = 62/371 (17%), Positives = 121/371 (33%), Gaps = 42/371 (11%)
Query 42 PAVANSV---ARKHGFLN-LGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLE 97
A+ + A + G++ + IF D + + ++ L P V+++E
Sbjct 95 EQTAHRLQTRAARRGYVIKVLHIFYDLFPGFLVKMSSDLLGLALKL-------PHVEYIE 147
Query 98 QQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG-IVVSILDDGI 156
+ + P W L + + + G + V +LD I
Sbjct 148 ED--------SFVFAQSIP-----WNLERIIPAWHQTEE--DRSPDGSSQVEVYLLDTSI 192
Query 157 EKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVA 216
+ H ++ G F+ ++ + + HGT AG V+ GVA
Sbjct 193 QGAHREIEGRVTI-TDFNSVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------AGVA 245
Query 217 YNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFR 276
+ +R+L+ + V +GL GP V P
Sbjct 246 KGTSLHSLRVLNCQGKGTVSGTLIGLEFIRKSQLIQPSGPL----VVLLPLAGGYSRILN 301
Query 277 GVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSST 336
+ G + V A+GN D+C ++ +++ + ++
Sbjct 302 AACRHLARTGVVLVAAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQPVTLGTLGTNF 358
Query 337 LATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHL 396
+ ++D C S +GTS +A AGI+A L LT +++
Sbjct 359 GRCVDLFAPGKDIIGASSDC-STCFMSQSGTSQAAAHVAGIVARMLSREPTLTLAELRQR 417
Query 397 VVQTSKPAHLN 407
++ S +N
Sbjct 418 LIHFSTKDVIN 428
>sp|Q07596|NISP_LACLL Nisin leader peptide-processing serine protease
NisP OS=Lactococcus lactis subsp. lactis OX=1360 GN=nisP
PE=1 SV=1
Length=682
Score = 104 bits (260), Expect = 6e-22, Method: Composition-based stats.
Identities = 74/374 (20%), Positives = 122/374 (33%), Gaps = 60/374 (16%)
Query 106 KRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG 165
K VY D + QW + VT N ++A I V I+D GI + HPDL+
Sbjct 217 KASVYTNSHD-FWDYQWDMKYVT----NNGESYALYQPSKKISVGIIDSGIMEEHPDLSN 271
Query 166 -------NYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYN 218
N P FD + D P ++ HGT AG++ A N +GVA
Sbjct 272 SLGNYFKNLVPKGGFDNEEPDETGNP-SDIVDKMGHGTEVAGQITANGN----ILGVAPG 326
Query 219 ARIGGVRMLDGEVTDAVEARSLGL---NPNHIHIYSASWGP--EDDGKTVDGPARLAEEA 273
+ R+ ++ + E + + + + + S G G DG E
Sbjct 327 ITVNIYRVFGENLSKS-EWVARAIRRAADDGNKVINISAGQYLMISGSYDDGTNDYQEYL 385
Query 274 FFRGVSQGRGGLGSIFVWASGNGGREHDSCN------------------CDGYTNSIYTL 315
++ GSI V A GN D + +
Sbjct 386 NYKSAINYATAKGSIVVAALGNDSLNIQDNQTMINFLKRFRSIKVPGKVVDAPSVFEDVI 445
Query 316 SISSATQFGNVPWYSEACSSTLAT--------------TYSSGNQNEKQIVTTDLRQKCT 361
++ +GN+ +S + + + S K + T
Sbjct 446 AVGGIDGYGNISDFSNIGADAIYAPAGTTANFKKYGQDKFVSQGYYLKDWLFTTANTGWY 505
Query 362 ESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAH----LNANDWATNGVG 417
+ G S + P +G +AL ++ ++ ++ S + LN D NG
Sbjct 506 QYVYGNSFATPKVSGALALVVDKYGIKNPNQLKRFLLMNSPEVNGNRVLNIVDL-LNGKN 564
Query 418 RKVSHSYGYGLLDA 431
+ S G DA
Sbjct 565 KAFSLDTDKGQDDA 578
>sp|P30199|EPIP_STAEP Epidermin leader peptide-processing serine
protease EpiP OS=Staphylococcus epidermidis OX=1282 GN=epiP
PE=3 SV=1
Length=461
Score = 103 bits (256), Expect = 7e-22, Method: Composition-based stats.
Identities = 66/413 (16%), Positives = 140/413 (34%), Gaps = 74/413 (18%)
Query 77 LSPHRPRHSRLQREPQVQWLE--------QQVAKRRTKRDVYQEPTDPKFPQQWYLSGVT 128
+ +S ++ V+++ ++ K + + + F +QW + +T
Sbjct 69 KTSKSKLNSLIKSNKNVKFVNPTCSTCVVEKSVKTGKNLNNKKNGSHDLFDRQWDMRKIT 128
Query 129 QRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG-----NYDPGASFDVNDQDPDPQ 183
N ++ V+++D G+ +H DL N P F ++ D
Sbjct 129 ----NEGKSYKLSPDRKKAKVALVDSGVNSSHTDLKSINKIVNEVPKNGFRGSENDESGN 184
Query 184 PRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDA--VEARSLG 241
+ + N HGT AG++ A N GV + R+ + ++ V +
Sbjct 185 KNFEEDKLN-HGTLVAGQIGANGN----LKGVNPGVEMNVYRVFGSKKSEMLWVSKGIID 239
Query 242 LNPNHIHIYSASWGP-----EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
+ + + S G + K + ++ +A + ++ GSI V A GN
Sbjct 240 AANDDNDVINVSLGNYLIKDNQNKKKLRDDEKVDYDALQKAINY-AQKKGSIVVAAVGND 298
Query 297 G---------REHDSCN-------CDGYTNSIYTLSISSATQFGNVPWYSEACSST---- 336
G + + N D N +++ S + +S ++
Sbjct 299 GINVKKVKEINKKRNLNSKTSKKVYDSPANLNNVMTVGSIDDNDYISEFSNYGNNFIDLM 358
Query 337 -------LATTYS------SGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE 383
L Y G ++ +++T + +GTS +AP +G +AL ++
Sbjct 359 TIGGSYKLLDKYGKDAWLEKGYMQKQSVLSTSSNGR-YIYQSGTSLAAPKVSGALALEID 417
Query 384 ANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
+ +D ++ K + + YG G LD ++
Sbjct 418 KYQ---LKDQPETAIELFKKKGIEKEKYMDKK-------HYGNGKLDVYKLLK 460
>sp|O53695|MYCP3_MYCTU Mycosin-3 OS=Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv) OX=83332 GN=mycP3 PE=1 SV=1
Length=461
Score = 101 bits (250), Expect = 4e-21, Method: Composition-based stats.
Identities = 76/370 (21%), Positives = 124/370 (34%), Gaps = 75/370 (20%)
Query 123 YLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDP 182
+ +Q LN+ AAW Q G G +V+I+D G++ P L N D G F +
Sbjct 66 GVPTPSQTMLNLPAAW-QFSRGEGQLVAIIDTGVQPG-PRL-PNVDAGGDFVES------ 116
Query 183 QPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGL 242
+ + HGT AG VA N GVA AR+ +R + + + L
Sbjct 117 --TDGLTDCDGHGTLVAGIVAGQPGND-GFSGVAPAARLLSIRAMSTKFSPRTSGGDPQL 173
Query 243 NPNHIHIYSASW----GPEDDGKTVDGPARLA--------EEAFFRGVSQGRGGLGSIFV 290
+ + + + K ++ + A + ++ V
Sbjct 174 AQATLDVAVLAGAIVHAADLGAKVINVSTITCLPADRMVDQAALGAAIRYAAVDKDAVIV 233
Query 291 WASGNGG------------------REHDSCNCDGYTNSI-------YTLSISSATQFGN 325
A+GN G R D N G T+ Y LS++S T G
Sbjct 234 AAAGNTGASGSVSASCDSNPLTDLSRPDDPRNWAGVTSVSIPSWWQPYVLSVASLTSAGQ 293
Query 326 VPWYS--------EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGI 377
+S A +A+ +SG+ + + + +GTS +A +G+
Sbjct 294 PSKFSMPGPWVGIAAPGENIASVSNSGDGALANGLPDA--HQKLVALSGTSYAAGYVSGV 351
Query 378 IALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVAL 437
AL L ++ + T+ R+ S+ G G LDA
Sbjct 352 AALVRSRYPGLNATEVVRRLTATAHRGA------------RESSNIVGAGNLDA----VA 395
Query 438 AQNWTTVAPQ 447
A W A
Sbjct 396 ALTWQLPAEP 405
>sp|Q69F34|SUB5_TRIRU Subtilisin-like protease 5 OS=Trichophyton
rubrum OX=5551 GN=SUB5 PE=2 SV=1
Length=396
Score = 99.1 bits (245), Expect = 8e-21, Method: Composition-based stats.
Identities = 60/348 (17%), Positives = 121/348 (35%), Gaps = 65/348 (19%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ +P+V ++E ++ V Q+ P W LS ++ R + G G
Sbjct 98 ISNDPKVAFVEPDAI--ISQHVVVQQRKAP-----WGLSRLSNRRGGRNYVFD-SSAGSG 149
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D G++ H + G G++ N + HGT AG +A
Sbjct 150 VWAYVVDSGVDIRHSEFQGRAVWGSNLVDNKN----------SDGTGHGTHVAGTIAGKT 199
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIH----------IYSASWGP 256
G+A A++ V++L+ E G+N + H + + S G
Sbjct 200 ------YGIAKKAKVVAVKVLNSEGKGPTSGIIAGINWSIRHARKHGMLQKSVLNMSLGG 253
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
A + G ++GN ++ + N + + +
Sbjct 254 TY-------------SAGLNHATAQAIKAGMFVSVSAGN---DNINSNGNSPASERSVCT 297
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAG 376
I+++T+ +S + Y+ G + + +++ +GTS +AP AAG
Sbjct 298 IAASTENDGKASFSNWGPA--VDLYAPG-----HNILSARPGGGSQTMSGTSMAAPHAAG 350
Query 377 IIALTLEA------NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ A + L + + ++ P + NG GR
Sbjct 351 VAAYLIAKEGIPGNRACLRLKQLSQPTIR--NPGPDTTSRLLYNGSGR 396
>sp|A8T6A6|PCSK9_LAGLA Proprotein convertase subtilisin/kexin
type 9 OS=Lagothrix lagotricha OX=9519 GN=PCSK9 PE=2 SV=1
Length=690
Score = 101 bits (251), Expect = 8e-21, Method: Composition-based stats.
Identities = 72/368 (20%), Positives = 121/368 (33%), Gaps = 47/368 (13%)
Query 45 ANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVA 101
A + A + G+L H +H + + R R P V ++E+
Sbjct 93 ARRLQAQAARRGYLIK------LLHVFHDLLPGFLVKMSRDLLELALRLPHVDYIEED-- 144
Query 102 KRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHP 161
+ P W L +T G + V +LD I+ H
Sbjct 145 ------SYVFAQSIP-----WNLERITPARYRADEYQPPN-GGSLVEVYLLDTSIQSGHR 192
Query 162 DLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARI 221
++ G F+ ++ + + HGT AG V+ GVA A +
Sbjct 193 EIEGRVM-VTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------AGVAKGASL 245
Query 222 GGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQG 281
+R+L+ + V + +GL + GP V P Q
Sbjct 246 RSLRVLNCQGKGTVSSTLIGLEFIRKNQLVQPVGPL----VVLLPLAGGYSRVLNAACQR 301
Query 282 RGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTY 341
G + V A+GN D+C ++ +++ + TL T +
Sbjct 302 LARAGVVLVAAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VTLGTLGTNF 353
Query 342 SS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDM-QHL 396
E I + C S +GTS +A AGI A+ L A LT ++ Q L
Sbjct 354 GRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRL 413
Query 397 VVQTSKPA 404
+ ++K
Sbjct 414 IHFSAKDV 421
>sp|A8T6A1|PCSK9_ATEGE Proprotein convertase subtilisin/kexin
type 9 OS=Ateles geoffroyi OX=9509 GN=PCSK9 PE=2 SV=1
Length=690
Score = 101 bits (251), Expect = 9e-21, Method: Composition-based stats.
Identities = 72/368 (20%), Positives = 121/368 (33%), Gaps = 47/368 (13%)
Query 45 ANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVA 101
A + A + G+L H +H + + R R P V ++E+
Sbjct 93 ARRLQAQAARRGYLIK------LLHVFHDLLPGFLVKMSRDLLELALRLPHVDYIEED-- 144
Query 102 KRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHP 161
+ P W L +T G + V +LD I+ H
Sbjct 145 ------SYVFAQSIP-----WNLERITPARYRADEYQPPN-GGSLVEVYLLDTSIQSGHR 192
Query 162 DLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARI 221
++ G F+ ++ + + HGT AG V+ GVA A +
Sbjct 193 EIEGRVM-VTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------AGVAKGASL 245
Query 222 GGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQG 281
+R+L+ + V + +GL + GP V P Q
Sbjct 246 RSLRVLNCQGKGTVSSTLIGLEFIRKNQLVQPVGPL----VVLLPLAGGYSRVLNAACQR 301
Query 282 RGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTY 341
G + V A+GN D+C ++ +++ + TL T +
Sbjct 302 LAKAGVVLVAAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VTLGTLGTNF 353
Query 342 SS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDM-QHL 396
E I + C S +GTS +A AGI A+ L A LT ++ Q L
Sbjct 354 GRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRL 413
Query 397 VVQTSKPA 404
+ ++K
Sbjct 414 IHFSAKDV 421
>sp|B8XGQ8|SUB5_TRITO Subtilisin-like protease 5 OS=Trichophyton
tonsurans OX=34387 GN=SUB5 PE=3 SV=1
Length=396
Score = 99.1 bits (245), Expect = 9e-21, Method: Composition-based stats.
Identities = 60/348 (17%), Positives = 121/348 (35%), Gaps = 65/348 (19%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ +P+V ++E ++ V Q+ P W LS ++ R + G G
Sbjct 98 ISNDPKVAFVEPDAI--ISQHVVVQQRKAP-----WGLSRLSNRRGGRNYVFD-SSAGSG 149
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D G++ H + G G++ N + HGT AG +A
Sbjct 150 VWAYVVDSGVDIRHSEFQGRAVWGSNLVDNKN----------SDGTGHGTHVAGTIAGKT 199
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIH----------IYSASWGP 256
G+A A++ V++L+ E G+N + H + + S G
Sbjct 200 ------YGIAKKAKVVAVKVLNSEGKGPTSGIIAGINWSIRHARKHGMLHKSVLNMSLGG 253
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
A + G ++GN ++ + N + + +
Sbjct 254 TY-------------SAGLNHATAQAIKAGMFVSVSAGN---DNINSNGNSPASERSVCT 297
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAG 376
I+++T+ +S + Y+ G + + +++ +GTS +AP AAG
Sbjct 298 IAASTENDGKASFSNWGPA--VDLYAPG-----HNILSARPGGGSQTMSGTSMAAPHAAG 350
Query 377 IIALTLEA------NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ A + L + + ++ P + NG GR
Sbjct 351 VAAYLIAKEGIPGNRACLRLKQLSQPTIR--NPGPDTTSRLLYNGSGR 396
>sp|B6VA87|SUB5_TRIEQ Subtilisin-like protease 5 OS=Trichophyton
equinum OX=63418 GN=SUB5 PE=3 SV=1
Length=396
Score = 99.1 bits (245), Expect = 9e-21, Method: Composition-based stats.
Identities = 60/348 (17%), Positives = 121/348 (35%), Gaps = 65/348 (19%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ +P+V ++E ++ V Q+ P W LS ++ R + G G
Sbjct 98 ISNDPKVAFVEPDAI--ISQHVVVQQRKAP-----WGLSRLSNRRGGRNYVFD-SSAGSG 149
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D G++ H + G G++ N + HGT AG +A
Sbjct 150 VWAYVVDSGVDIRHSEFQGRAVWGSNLVDNKN----------SDGTGHGTHVAGTIAGKT 199
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIH----------IYSASWGP 256
G+A A++ V++L+ E G+N + H + + S G
Sbjct 200 ------YGIAKKAKVVAVKVLNSEGKGPTSGIIAGINWSIRHARKHGMLHKSVLNMSLGG 253
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
A + G ++GN ++ + N + + +
Sbjct 254 TY-------------SAGLNHATAQAIKAGMFVSVSAGN---DNINSNGNSPASERSVCT 297
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAG 376
I+++T+ +S + Y+ G + + +++ +GTS +AP AAG
Sbjct 298 IAASTENDGKASFSNWGPA--VDLYAPG-----HNILSARPGGGSQTMSGTSMAAPHAAG 350
Query 377 IIALTLEA------NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ A + L + + ++ P + NG GR
Sbjct 351 VAAYLIAKEGIPGNRACLRLKQLSQPTIR--NPGPDTTSRLLYNGSGR 396
>sp|D4D0F5|SUB5_TRIVH Subtilisin-like protease 5 OS=Trichophyton
verrucosum (strain HKI 0517) OX=663202 GN=SUB5 PE=3 SV=1
Length=396
Score = 98.7 bits (244), Expect = 1e-20, Method: Composition-based stats.
Identities = 60/348 (17%), Positives = 121/348 (35%), Gaps = 65/348 (19%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ +P+V ++E ++ V Q+ P W LS ++ R + G G
Sbjct 98 ISNDPKVAFVEPDAI--ISQHVVVQQRKAP-----WGLSRLSNRRGGRNYVFD-SSAGSG 149
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D G++ H + G G++ N + HGT AG +A
Sbjct 150 VWAYVVDSGVDVRHAEFQGRAVWGSNLVDNKN----------SDGTGHGTHVAGTIAGKT 199
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIH----------IYSASWGP 256
G+A A++ V++L+ E G+N + H + + S G
Sbjct 200 ------YGIAKKAKVVAVKVLNSEGKGPTSGIIAGINWSIRHARKHGMLQKSVLNMSLGG 253
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
A + G ++GN ++ + N + + +
Sbjct 254 TY-------------SAGLNHATAQAIKAGMFVSVSAGN---DNINSNGNSPASERSVCT 297
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAG 376
I+++T+ +S + Y+ G + + +++ +GTS +AP AAG
Sbjct 298 IAASTENDGKASFSNWGPA--VDLYAPG-----HNILSARPGGGSQTMSGTSMAAPHAAG 350
Query 377 IIALTLEA------NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ A + L + + ++ P + NG GR
Sbjct 351 VAAYLIAKEGIPGNRACLRLKQLSQPTIR--NPGPDTTSRLLYNGSGR 396
>sp|Q5VJ73|SUB5_TRIVC Subtilisin-like protease 5 OS=Trichophyton
verrucosum OX=63417 GN=SUB5 PE=3 SV=1
Length=396
Score = 98.7 bits (244), Expect = 1e-20, Method: Composition-based stats.
Identities = 60/348 (17%), Positives = 121/348 (35%), Gaps = 65/348 (19%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ +P+V ++E ++ V Q+ P W LS ++ R + G G
Sbjct 98 ISNDPKVAFVEPDAI--ISQHVVVQQRKAP-----WGLSRLSNRRGGRNYVFD-SSAGSG 149
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D G++ H + G G++ N + HGT AG +A
Sbjct 150 VWAYVVDSGVDVRHAEFQGRAVWGSNLVDNKN----------SDGTGHGTHVAGTIAGKT 199
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIH----------IYSASWGP 256
G+A A++ V++L+ E G+N + H + + S G
Sbjct 200 ------YGIAKKAKVVAVKVLNSEGKGPTSGIIAGINWSIRHARKHGMLQKSVLNMSLGG 253
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
A + G ++GN ++ + N + + +
Sbjct 254 TY-------------SAGLNHATAQAIKAGMFVSVSAGN---DNINSNGNSPASERSVCT 297
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAG 376
I+++T+ +S + Y+ G + + +++ +GTS +AP AAG
Sbjct 298 IAASTENDGKASFSNWGPA--VDLYAPG-----HNILSARPGGGSQTMSGTSMAAPHAAG 350
Query 377 IIALTLEA------NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ A + L + + ++ P + NG GR
Sbjct 351 VAAYLIAKEGIPGNRACLRLKQLSQPTIR--NPGPDTTSRLLYNGSGR 396
>sp|Q64K32|SUB5_ARTBE Subtilisin-like protease 5 OS=Arthroderma
benhamiae OX=63400 GN=SUB5 PE=3 SV=1
Length=396
Score = 98.7 bits (244), Expect = 1e-20, Method: Composition-based stats.
Identities = 60/348 (17%), Positives = 120/348 (34%), Gaps = 65/348 (19%)
Query 87 LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHG 146
+ +P+V ++E ++ V Q+ P W LS ++ R + G G
Sbjct 98 ISNDPKVAFVEPDAI--ISQHVVVQQRKAP-----WGLSRLSNRRGGRNYVFD-SSAGSG 149
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVA 206
+ ++D G++ H + G G++ N + HGT AG +A
Sbjct 150 VWAYVVDSGVDVRHAEFQGRAVWGSNLVDNKN----------SDGTGHGTHVAGTIAGKT 199
Query 207 NNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIH----------IYSASWGP 256
G+A A++ V++L+ E G+N + H + + S G
Sbjct 200 ------YGIAKKAKVVAVKVLNSEGKGPTSGIIAGINWSIRHARKHGMLQKSVLNMSLGG 253
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
A + G ++GN ++ + N + + +
Sbjct 254 TY-------------SAGLNHATAQAIKAGMFVSVSAGN---DNINSNGNSPASERSVCT 297
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAG 376
I+++T+ +S + Y+ G + + +++ +GTS +AP AAG
Sbjct 298 IAASTENDGKASFSNWGPA--VDLYAPG-----HNILSARPGGGSQTMSGTSMAAPHAAG 350
Query 377 IIALTLEA------NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
+ A + L + + ++ P NG GR
Sbjct 351 VAAYLIAKEGIPGNRACLRLKQLSQPTIR--NPGPDTTTRLLYNGSGR 396
>sp|A8T677|PCSK9_PLEMO Proprotein convertase subtilisin/kexin
type 9 OS=Plecturocebus moloch OX=9523 GN=PCSK9 PE=2 SV=1
Length=684
Score = 100 bits (249), Expect = 2e-20, Method: Composition-based stats.
Identities = 69/373 (18%), Positives = 119/373 (32%), Gaps = 39/373 (10%)
Query 36 VRIPGGPAVANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQ 92
A + A + G+L H +H + + R R P
Sbjct 85 AHRSQPERTARRLQAQAARRGYLIK------LLHVFHHLLPGFLVKMSRDLLELALRLPH 138
Query 93 VQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSIL 152
V ++E+ + P W L +T G + V +L
Sbjct 139 VDYIEED--------SSVFAQSIP-----WNLERITPARYRADEYQPPN-GGSLVEVYLL 184
Query 153 DDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCG 212
D I+ +H ++ G F+ ++ + + HGT AG V+
Sbjct 185 DTSIQSSHREIEGRVM-VTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------ 237
Query 213 VGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEE 272
GVA A + + +L+ + V + +GL GP V P
Sbjct 238 AGVAKGASLRSLHVLNCQGKGTVSSALIGLEFIRKSQLVQPVGPL----VVLLPLAGGYS 293
Query 273 AFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEA 332
+ G G + V A+GN D+C ++ +++ + P
Sbjct 294 RVLNAACRRLAGAGVVLVAAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQ-PLTLGT 349
Query 333 CSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRD 392
+ E I + C S +GTS +A AGI A+ L A LT +
Sbjct 350 LGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAE 409
Query 393 M-QHLVVQTSKPA 404
+ Q L+ ++K
Sbjct 410 LRQRLIHFSAKDV 422
>sp|A8T688|PCSK9_CALJA Proprotein convertase subtilisin/kexin
type 9 OS=Callithrix jacchus OX=9483 GN=PCSK9 PE=2 SV=1
Length=690
Score = 99.5 bits (246), Expect = 4e-20, Method: Composition-based stats.
Identities = 72/368 (20%), Positives = 119/368 (32%), Gaps = 47/368 (13%)
Query 45 ANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVA 101
A + A + G+L H +H + + R R P V ++E+
Sbjct 93 ARRLQAQAARRGYLIK------LLHVFHDLLPGFLVKMSRDLLELALRLPHVDYIEED-- 144
Query 102 KRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHP 161
+ P W L +T G + V +LD I+ H
Sbjct 145 ------SSVFAQSIP-----WNLERITPARYRADEYQPPN-GGSLVEVYLLDTSIQSGHR 192
Query 162 DLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARI 221
++ G F ++ + + HGT AG V+ GVA A +
Sbjct 193 EIEGRVM-VTDFGSVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------AGVAKGASL 245
Query 222 GGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQG 281
+R+L+ + V + +GL GP V P Q
Sbjct 246 RSLRVLNCQGKGTVSSTLIGLEFIRKSQLVQPVGPL----VVLLPLAGGYSRVLNAACQR 301
Query 282 RGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTY 341
G + V A+GN D+C ++ +++ + TL T +
Sbjct 302 LARAGVVLVAAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VTLGTLGTNF 353
Query 342 SS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDM-QHL 396
E I + C S +GTS +A AGI A+ L A LT ++ Q L
Sbjct 354 GRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAKPELTLAELRQRL 413
Query 397 VVQTSKPA 404
+ ++K
Sbjct 414 IHFSAKDV 421
>sp|A8T644|PCSK9_PANTR Proprotein convertase subtilisin/kexin
type 9 OS=Pan troglodytes OX=9598 GN=PCSK9 PE=2 SV=1
Length=692
Score = 98.3 bits (243), Expect = 7e-20, Method: Composition-based stats.
Identities = 69/376 (18%), Positives = 119/376 (32%), Gaps = 47/376 (13%)
Query 37 RIPGGPAVANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQV 93
+ A + A + G+ H +H + + + P V
Sbjct 87 HLSQSERTARRLQAQAARRGY------LTKILHVFHGLLPGFLVKMSGDLLELALKLPHV 140
Query 94 QWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILD 153
++E+ + P W L +T G + V +LD
Sbjct 141 DYIEED--------SSVFAQSIP-----WNLERITPPRYRADEYQPPD-GGSLVEVYLLD 186
Query 154 DGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGV 213
I+ +H ++ G F+ ++ + + HGT AG V+
Sbjct 187 TSIQSDHREIEGRVM-VTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------A 239
Query 214 GVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEA 273
GVA A + +R+L+ + V +GL GP V P
Sbjct 240 GVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPL----VVLLPLAGGYSR 295
Query 274 FFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEAC 333
Q G + V A+GN D+C ++ +++ +
Sbjct 296 VLNAACQRLARAGVVLVTAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VT 347
Query 334 SSTLATTYSS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLT 389
TL T + E I + C S +GTS +A AGI A+ L A LT
Sbjct 348 LGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELT 407
Query 390 WRDM-QHLVVQTSKPA 404
++ Q L+ ++K
Sbjct 408 LAELRQRLIHFSAKDV 423
>sp|A8T650|PCSK9_GORGO Proprotein convertase subtilisin/kexin
type 9 OS=Gorilla gorilla gorilla OX=9595 GN=PCSK9 PE=2 SV=1
Length=690
Score = 98.3 bits (243), Expect = 8e-20, Method: Composition-based stats.
Identities = 69/376 (18%), Positives = 119/376 (32%), Gaps = 47/376 (13%)
Query 37 RIPGGPAVANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQV 93
+ A + A + G+ H +H + + + P V
Sbjct 85 HLSQSERTARRLQAQAARRGY------LTKILHVFHGLLPGFLVKMSGDLLELALKLPHV 138
Query 94 QWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILD 153
++E+ + P W L +T G + V +LD
Sbjct 139 DYIEED--------SSVFAQSIP-----WNLERITPPRYRADEYQPPD-GGSLVEVYLLD 184
Query 154 DGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGV 213
I+ +H ++ G F+ ++ + + HGT AG V+
Sbjct 185 TSIQSDHREIEGRVM-VTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------A 237
Query 214 GVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEA 273
GVA A + +R+L+ + V +GL GP V P
Sbjct 238 GVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPL----VVLLPLAGGYSR 293
Query 274 FFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEAC 333
Q G + V A+GN D+C ++ +++ +
Sbjct 294 VLNAACQRLARAGVVLVTAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VT 345
Query 334 SSTLATTYSS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLT 389
TL T + E I + C S +GTS +A AGI A+ L A LT
Sbjct 346 LGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELT 405
Query 390 WRDM-QHLVVQTSKPA 404
++ Q L+ ++K
Sbjct 406 LAELRQRLIHFSAKDV 421
>sp|Q8NBP7|PCSK9_HUMAN Proprotein convertase subtilisin/kexin
type 9 OS=Homo sapiens OX=9606 GN=PCSK9 PE=1 SV=3
Length=692
Score = 98.0 bits (242), Expect = 1e-19, Method: Composition-based stats.
Identities = 69/376 (18%), Positives = 119/376 (32%), Gaps = 47/376 (13%)
Query 37 RIPGGPAVANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQV 93
+ A + A + G+ H +H + + + P V
Sbjct 87 HLSQSERTARRLQAQAARRGY------LTKILHVFHGLLPGFLVKMSGDLLELALKLPHV 140
Query 94 QWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILD 153
++E+ + P W L +T G + V +LD
Sbjct 141 DYIEED--------SSVFAQSIP-----WNLERITPPRYRADEYQPPD-GGSLVEVYLLD 186
Query 154 DGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGV 213
I+ +H ++ G F+ ++ + + HGT AG V+
Sbjct 187 TSIQSDHREIEGRVM-VTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------A 239
Query 214 GVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEA 273
GVA A + +R+L+ + V +GL GP V P
Sbjct 240 GVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPL----VVLLPLAGGYSR 295
Query 274 FFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEAC 333
Q G + V A+GN D+C ++ +++ +
Sbjct 296 VLNAACQRLARAGVVLVTAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VT 347
Query 334 SSTLATTYSS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLT 389
TL T + E I + C S +GTS +A AGI A+ L A LT
Sbjct 348 LGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELT 407
Query 390 WRDM-QHLVVQTSKPA 404
++ Q L+ ++K
Sbjct 408 LAELRQRLIHFSAKDV 423
>sp|A8T695|PCSK9_SAIBB Proprotein convertase subtilisin/kexin
type 9 OS=Saimiri boliviensis boliviensis OX=39432 GN=PCSK9
PE=2 SV=1
Length=691
Score = 98.0 bits (242), Expect = 1e-19, Method: Composition-based stats.
Identities = 71/368 (19%), Positives = 119/368 (32%), Gaps = 47/368 (13%)
Query 45 ANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVA 101
A + A + G+L H +H + + R + P V ++E+
Sbjct 94 ARRLQAQAARRGYLIK------LLHVFHDLLPGFLVKMSRDLLELALKLPHVDYIEED-- 145
Query 102 KRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHP 161
+ P W L +T G + V +LD I+ H
Sbjct 146 ------SSVFAQSIP-----WNLERITPARYRADEYQPPN-GGSLVEVYLLDTSIQSGHR 193
Query 162 DLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARI 221
++ G F ++ + + HGT AG V+ GVA A +
Sbjct 194 EIEGRVM-VTDFGSVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------AGVAKGASL 246
Query 222 GGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQG 281
+R+L+ + V + +GL GP V P Q
Sbjct 247 RSLRVLNCQGKGTVSSTLIGLEFIRKSQLVQPVGPL----VVLLPLAGGYSRVLNAACQR 302
Query 282 RGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTY 341
G + V A+GN D+C ++ +++ + TL T +
Sbjct 303 LARAGVVLVAAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VTLGTLGTNF 354
Query 342 SS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDM-QHL 396
E I + C S +GTS +A AGI A+ L A LT ++ Q L
Sbjct 355 GRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAVMLSAEPELTLAELRQRL 414
Query 397 VVQTSKPA 404
+ ++K
Sbjct 415 IHFSAKDV 422
>sp|A8T672|PCSK9_COLGU Proprotein convertase subtilisin/kexin
type 9 OS=Colobus guereza OX=33548 GN=PCSK9 PE=2 SV=1
Length=692
Score = 97.6 bits (241), Expect = 1e-19, Method: Composition-based stats.
Identities = 70/376 (19%), Positives = 120/376 (32%), Gaps = 47/376 (13%)
Query 37 RIPGGPAVANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQV 93
A + A + G+ H +H + + + P V
Sbjct 87 HRSQSERTARRLQAQAARRGY------LTKILHVFHHLLPGFLVKMSGDLLELALKLPHV 140
Query 94 QWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILD 153
++E+ + P W L +T + G + V +LD
Sbjct 141 DYIEED--------SSVFAQSIP-----WNLERITPARYRADE-YQPPKGGSLVEVYLLD 186
Query 154 DGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGV 213
I+ +H ++ G F+ ++ + + HGT AG V+
Sbjct 187 TSIQSDHREIEGRVM-VTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------A 239
Query 214 GVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEA 273
GVA A + +R+L+ + V +GL GP V P
Sbjct 240 GVAKGAGLRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPL----VVLLPLAGGYSR 295
Query 274 FFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEAC 333
F Q G + V A+GN D+C ++ +++ +
Sbjct 296 VFNAACQRLARAGVVLVTAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VT 347
Query 334 SSTLATTYSS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLT 389
TL T + E I + C S +GTS +A AGI A+ L A LT
Sbjct 348 LGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELT 407
Query 390 WRDM-QHLVVQTSKPA 404
++ Q L+ ++K
Sbjct 408 LAELRQRLIHFSAKDV 423
>sp|A8T666|PCSK9_MACMU Proprotein convertase subtilisin/kexin
type 9 OS=Macaca mulatta OX=9544 GN=PCSK9 PE=2 SV=1
Length=692
Score = 97.2 bits (240), Expect = 2e-19, Method: Composition-based stats.
Identities = 70/376 (19%), Positives = 120/376 (32%), Gaps = 47/376 (13%)
Query 37 RIPGGPAVANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQV 93
A + A + G+ H +H + + + P V
Sbjct 87 HRSQSERTARRLQAQAARRGY------LTKILHVFHHLLPGFLVKMSGDLLELALKLPHV 140
Query 94 QWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILD 153
++E+ + P W L +T + G + V +LD
Sbjct 141 DYIEED--------SSVFAQSIP-----WNLERITPARYRADE-YQPPKGGSLVEVYLLD 186
Query 154 DGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGV 213
I+ +H ++ G F+ ++ + + HGT AG V+
Sbjct 187 TSIQSDHREIEGRVM-VTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------A 239
Query 214 GVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEA 273
GVA A + +R+L+ + V +GL GP V P
Sbjct 240 GVAKGAGLRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPL----VVLLPLAGGYSR 295
Query 274 FFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEAC 333
F Q G + V A+GN D+C ++ +++ +
Sbjct 296 VFNAACQRLARAGVVLVTAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VT 347
Query 334 SSTLATTYSS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLT 389
TL T + E I + C S +GTS +A AGI A+ L A LT
Sbjct 348 LGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELT 407
Query 390 WRDM-QHLVVQTSKPA 404
++ Q L+ ++K
Sbjct 408 LAELRQRLIHFSAKDV 423
>sp|A8T662|PCSK9_MACNE Proprotein convertase subtilisin/kexin
type 9 OS=Macaca nemestrina OX=9545 GN=PCSK9 PE=2 SV=1
Length=692
Score = 97.2 bits (240), Expect = 2e-19, Method: Composition-based stats.
Identities = 70/376 (19%), Positives = 120/376 (32%), Gaps = 47/376 (13%)
Query 37 RIPGGPAVANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQV 93
A + A + G+ H +H + + + P V
Sbjct 87 HRSQSERTARRLQAQAARRGY------LTKILHVFHHLLPGFLVKMSGDLLELALKLPHV 140
Query 94 QWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILD 153
++E+ + P W L +T + G + V +LD
Sbjct 141 DYIEED--------SSVFAQSIP-----WNLERITPARYRADE-YQPPKGGSLVEVYLLD 186
Query 154 DGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGV 213
I+ +H ++ G F+ ++ + + HGT AG V+
Sbjct 187 TSIQSDHREIEGRVM-VTDFESVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------A 239
Query 214 GVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEA 273
GVA A + +R+L+ + V +GL GP V P
Sbjct 240 GVAKGAGLRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPL----VVLLPLAGGYSR 295
Query 274 FFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEAC 333
F Q G + V A+GN D+C ++ +++ +
Sbjct 296 VFNAACQRLARAGVVLVTAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VT 347
Query 334 SSTLATTYSS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLT 389
TL T + E I + C S +GTS +A AGI A+ L A LT
Sbjct 348 LGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELT 407
Query 390 WRDM-QHLVVQTSKPA 404
++ Q L+ ++K
Sbjct 408 LAELRQRLIHFSAKDV 423
>sp|A0QNL1|MYCP1_MYCS2 Mycosin-1 OS=Mycolicibacterium smegmatis
(strain ATCC 700084 / mc(2)155) OX=246196 GN=mycP1 PE=1 SV=1
Length=449
Score = 95.7 bits (236), Expect = 2e-19, Method: Composition-based stats.
Identities = 63/373 (17%), Positives = 114/373 (31%), Gaps = 73/373 (20%)
Query 143 TGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEV 202
TG G+ V+++D G+ + D D + + + HGT A +
Sbjct 82 TGAGVTVAVIDTGVNGS-----PRVPAEPGGDFVDAAGNGM-----SDCDAHGTMTAAII 131
Query 203 AAVANNGVCGVGVAYNARIGGVRM--------------LDGEVTDAVE-----ARSLGLN 243
+ VG+A + R+ +R D T ARS+
Sbjct 132 GGRPSPTDGFVGMAPDVRLLSLRQTSVAFQPKGARQDPNDPNTTQTAGSIRSLARSVVHA 191
Query 244 PN-HIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDS 302
N + + S + R+ E + ++ G++ V A+GN G++
Sbjct 192 ANLGAQVINIS-----EAACYKVTRRIDETSLGAAINYAVNVKGAVIVVAAGNTGQDCSQ 246
Query 303 CNCDGYTNSIY-------------------TLSISSATQFGNVPWYSEACSSTLATTYS- 342
+ L++ S Q G +S + A
Sbjct 247 NPPPDPSVPSDPRGWREVQTIVSPAWYDPLVLTVGSIGQNGQPSNFSMSGPWVGAAAPGE 306
Query 343 --SGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQT 400
+ + Q V + GTS SA +G+ AL + +LT + + + T
Sbjct 307 NLTSLGYDGQPVNATPGEDGPVPLNGTSFSAAYVSGLAALVKQRFPDLTPAQIINRITAT 366
Query 401 SKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKD 460
++ G V + G G++D A W K + P
Sbjct 367 ARH------------PGGGVDNYVGAGVIDP----VAALTWEIPDGPEKAPFRVKEVPPP 410
Query 461 IGKRLEVRKTVTA 473
+ R +TA
Sbjct 411 VYIPPPDRGPITA 423
>sp|A8T682|PCSK9_SAGLB Proprotein convertase subtilisin/kexin
type 9 OS=Saguinus labiatus OX=78454 GN=PCSK9 PE=2 SV=1
Length=686
Score = 96.4 bits (238), Expect = 3e-19, Method: Composition-based stats.
Identities = 71/368 (19%), Positives = 123/368 (33%), Gaps = 47/368 (13%)
Query 45 ANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVA 101
A + A + G+L H +H + + R R P V ++E+
Sbjct 93 ARRLQAQAARRGYLIK------LLHVFHDLLPGFLVKMSRDLLELALRLPHVDYIEED-- 144
Query 102 KRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHP 161
+ P W L +T G + V +LD I+ H
Sbjct 145 ------SSVFAQSIP-----WNLERITPARYQADEYQPPN-GGSLVEVYLLDTSIQSGHR 192
Query 162 DLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARI 221
++ G F ++ + + HGT AG V+ GVA A +
Sbjct 193 EIEGRVM-VTDFGSVPKEDGTRFHRQASKCDSHGTHLAGVVSGRD------AGVAKGASL 245
Query 222 GGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQG 281
+R+L+ + V + +GL GP + G A + +++
Sbjct 246 HSLRVLNCQGKGTVSSTLIGLEFICKSQLVQPVGPLVVLLPLAGGYSRVLNAACQRLARA 305
Query 282 RGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTY 341
R + V A+GN D+C ++ +++ + TL T +
Sbjct 306 R----VVLVAAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VTLGTLGTNF 353
Query 342 SS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDM-QHL 396
E I + C S +GTS +A AGI A+ L A LT ++ Q L
Sbjct 354 GRCVDLFAPGEDIIGASSDCSTCFVSRSGTSQAAAHVAGIAAMMLSAEPELTLAELRQRL 413
Query 397 VVQTSKPA 404
+ ++K
Sbjct 414 IHFSAKDV 421
>sp|A8T655|PCSK9_PANPA Proprotein convertase subtilisin/kexin
type 9 OS=Pan paniscus OX=9597 GN=PCSK9 PE=2 SV=2
Length=692
Score = 96.0 bits (237), Expect = 4e-19, Method: Composition-based stats.
Identities = 69/376 (18%), Positives = 118/376 (31%), Gaps = 47/376 (13%)
Query 37 RIPGGPAVANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQV 93
+ A + A G+ H +H + + + P V
Sbjct 87 HLSQSERTARRLQAQAAHRGY------LTKILHVFHGLLPGFLVKMSGDLLELALKLPHV 140
Query 94 QWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILD 153
++E+ + P W L +T G + V +LD
Sbjct 141 DYIEED--------SSVFAQSIP-----WNLERITPPRYRADEYQPPD-GGSLVEVYLLD 186
Query 154 DGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGV 213
I+ +H ++ G F+ ++ + + HGT AG V+
Sbjct 187 TSIQSDHREIEGRVM-VTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------A 239
Query 214 GVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEA 273
GVA A + +R+L+ + V +GL GP V P
Sbjct 240 GVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVRPVGPL----VVLLPLAGGYSR 295
Query 274 FFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEAC 333
Q G + V A+GN D+C ++ +++ +
Sbjct 296 VLNAACQRLARAGVVLVTAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VT 347
Query 334 SSTLATTYSS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLT 389
TL T + E I + C S +GTS +A AGI A+ L A LT
Sbjct 348 LGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSAEPELT 407
Query 390 WRDM-QHLVVQTSKPA 404
++ Q L+ ++K
Sbjct 408 LAELRQRLIHFSAKDV 423
>sp|E6MVD9|NALP_NEIMH Neisserial autotransporter lipoprotein NalP
OS=Neisseria meningitidis serogroup B / serotype 15 (strain
H44/76) OX=909420 GN=nalP PE=1 SV=1
Length=1083
Score = 96.4 bits (238), Expect = 4e-19, Method: Composition-based stats.
Identities = 71/381 (19%), Positives = 129/381 (34%), Gaps = 90/381 (24%)
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIE---KNHPDLAG-----------NY---------- 167
+N+K A GYTG G+ V I+D G + P+L G NY
Sbjct 118 INLKPAIEAGYTGRGVEVGIVDTGESVGSISFPELYGRKEHGYNENYKNYTAYMRKEAPE 177
Query 168 -----DPGASFD---VNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNA 219
D ASFD V + + P + + H + + + +G G+A +A
Sbjct 178 DGGGKDIEASFDDEAVIETEAKPTD-IRHVKEIGHIDLVSHIIGGRSVDGRPAGGIAPDA 236
Query 220 RIGGVRMLDGEVTDAVEARS----LGLNPNHIHIYSASWGPEDDGKT------------- 262
+ + DG + + A + L + I + S+G T
Sbjct 237 TLHIMNTNDGTKNEMMVAAIRNAWVKLGERGVRIVNNSFGTTSRAGTADLFQIANSEEQY 296
Query 263 ------------VDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNC----- 305
D RL +++ + +S +F++++GN + +
Sbjct 297 RQALLDYSGGDKTDEGIRLMQQSDYGNLSYHIRNKNMLFIFSTGNDAQAQPNTYALLPFY 356
Query 306 --DGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTES 363
D I + + + Y E + L Y S + + + +
Sbjct 357 EKDAQKGIITVAGVDRSGEKFKREMYGEPGTEPLE--YGSNHCGITAMWCLSAPYEASVR 414
Query 364 HT--------GTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNG 415
T GTS SAP+ G AL L+ ++ +++ ++ T++
Sbjct 415 FTRTNPIQIAGTSFSAPIVTGTAALLLQKYPWMSNDNLRTTLLTTAQDIGAVG------- 467
Query 416 VGRKVSHSYGYGLLDAGAMVA 436
V +G+GLLDAG +
Sbjct 468 ----VDSKFGWGLLDAGKAMN 484
>sp|P15293|P2P_LACLC PII-type proteinase OS=Lactococcus lactis
subsp. cremoris OX=1359 GN=prt PE=3 SV=1
Length=1902
Score = 95.7 bits (236), Expect = 1e-18, Method: Composition-based stats.
Identities = 55/277 (20%), Positives = 93/277 (34%), Gaps = 57/277 (21%)
Query 133 NVKAAWAQ-GYTGHGIVVSILDDGIEKNHPDLA-----------------------GNY- 167
NV+A W+ Y G G VVS++D GI+ H D+ G Y
Sbjct 196 NVQAVWSNYKYKGEGTVVSVIDSGIDPTHKDMRLSDDKDVKLTKSDVEKFTDTAKHGRYF 255
Query 168 DPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVC------GVGVAYNARI 221
+ + N D + D +HG AG + A NG VGVA A++
Sbjct 256 NSKVPYGFNYADNN-DTITDDTVDEQHGMHVAGIIGA---NGTGDDPAKSVVGVAPEAQL 311
Query 222 GGVRMLDGEVTDAV--EARSLGLNPN----HIHIYSASWGPEDDGKTVDGPARLAEEAFF 275
+++ T A A + + + + S G + +T++ P
Sbjct 312 LAMKVFTNSDTSATTGSATLVSAIEDSAKIGADVLNMSLGSDSGNQTLEDP--------E 363
Query 276 RGVSQGRGGLGSIFVWASGNGGREHD-----SCNCDGYTNSIYTLSISSATQFGNVPWYS 330
Q G+ V ++GN G + + G ++ + ++ V
Sbjct 364 LAAVQNANESGTAAVISAGNSGTSGSATEGVNKDYYGLQDNEMVGTPGTSRGATTVASAE 423
Query 331 EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGT 367
T A T + G + T L + TG+
Sbjct 424 NTDVITQAVTITDGTGLQLGPETIQL---SSNDFTGS 457
Score = 38.3 bits (87), Expect = 0.42, Method: Composition-based stats.
Identities = 30/165 (18%), Positives = 56/165 (34%), Gaps = 19/165 (12%)
Query 320 ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIA 379
T+ + S S L+ + + + +GTS ++P AG A
Sbjct 574 YTEDKMSDFTSYGPVSNLSFKPDITAPGGN--IWSTQNNNGYTNMSGTSMASPFIAGSQA 631
Query 380 LTLEA-----------NKNLTWRDMQHLV--VQTSKPAHLNANDWATNGVGRKVSHSYGY 426
L +A K L + + V+ + +N ++ V + G
Sbjct 632 LLKQALNNKNNPFYAYYKQLKGTALTDFLKTVEMNTAQPINDINYNNVIVSPR---RQGA 688
Query 427 GLLDAGAMVA-LAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKT 470
GL+D A + L +N +TV + L + K ++ T
Sbjct 689 GLVDVKAAIDALEKNPSTVVAENGYPAVELKDFTSTDKTFKLTFT 733
>sp|A8T658|PCSK9_PONPY Proprotein convertase subtilisin/kexin
type 9 OS=Pongo pygmaeus OX=9600 GN=PCSK9 PE=2 SV=1
Length=690
Score = 94.5 bits (233), Expect = 1e-18, Method: Composition-based stats.
Identities = 68/376 (18%), Positives = 117/376 (31%), Gaps = 47/376 (13%)
Query 37 RIPGGPAVANSV---ARKHGFLNLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQV 93
A + A + G+ H +H + + + P V
Sbjct 85 HRSQSERTARRLQAQAARRGY------LTKILHVFHDLLPGFLVKMSGDLLELALKLPHV 138
Query 94 QWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILD 153
++E+ + P W L +T G + V +LD
Sbjct 139 DYIEED--------SSVFAQSIP-----WNLERITPPRYRADEYQPPD-GGSLVEVYLLD 184
Query 154 DGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGV 213
I+ +H ++ G F+ ++ + + HGT AG V+
Sbjct 185 TSIQSDHREIEGRVM-VTDFENVPEEDGTRFHRQASKCDSHGTHLAGVVSGRD------A 237
Query 214 GVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEA 273
GVA A + +R+L+ + V +GL GP V P
Sbjct 238 GVAKGASMRSLRVLNCQGKGTVSGTLIGLEFIRKSQLVQPVGPL----VVLMPLAGGYSR 293
Query 274 FFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEAC 333
Q G + V A+GN D+C ++ +++ +
Sbjct 294 VLNAACQRLARAGVVLVTAAGN--FRDDACLYSP-ASAPEVITVGATNAQDQP-----VT 345
Query 334 SSTLATTYSS----GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLT 389
TL T + E I + C S +GTS +A AGI A+ L LT
Sbjct 346 LGTLGTNFGRCVDLFAPGEDIIGASSDCSTCFVSQSGTSQAAAHVAGIAAMMLSVEPELT 405
Query 390 WRDM-QHLVVQTSKPA 404
++ Q L+ ++K
Sbjct 406 LAELRQRLIHFSAKDV 421
>sp|P16271|P1P_LACLC PI-type proteinase OS=Lactococcus lactis
subsp. cremoris OX=1359 GN=prtP PE=3 SV=1
Length=1902
Score = 95.3 bits (235), Expect = 1e-18, Method: Composition-based stats.
Identities = 55/277 (20%), Positives = 93/277 (34%), Gaps = 57/277 (21%)
Query 133 NVKAAWAQ-GYTGHGIVVSILDDGIEKNHPDLA-----------------------GNY- 167
NV+A W+ Y G G VVS++D GI+ H D+ G Y
Sbjct 196 NVQAVWSNYKYKGEGTVVSVIDSGIDPTHKDMRLSDDKDVKLTKSDVEKFTDTAKHGRYF 255
Query 168 DPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVC------GVGVAYNARI 221
+ + N D + D +HG AG + A NG VGVA A++
Sbjct 256 NSKVPYGFNYADNN-DTITDDTVDEQHGMHVAGIIGA---NGTGDDPAKSVVGVAPEAQL 311
Query 222 GGVRMLDGEVTDAVEARSLGLNP------NHIHIYSASWGPEDDGKTVDGPARLAEEAFF 275
+++ T A S ++ + + S G + +T++ P
Sbjct 312 LAMKVFTNSDTSATTGSSTLVSAIEDSAKIGADVLNMSLGSDSGNQTLEDP--------E 363
Query 276 RGVSQGRGGLGSIFVWASGNGGREHD-----SCNCDGYTNSIYTLSISSATQFGNVPWYS 330
Q G+ V ++GN G + + G ++ + ++ V
Sbjct 364 LAAVQNANESGTAAVISAGNSGTSGSATEGVNKDYYGLQDNEMVGTPGTSRGATTVASAE 423
Query 331 EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGT 367
T A T + G + T L + TG+
Sbjct 424 NTDVITQAVTITDGTGLQLGPGTIQL---SSNDFTGS 457
Score = 38.3 bits (87), Expect = 0.41, Method: Composition-based stats.
Identities = 30/165 (18%), Positives = 56/165 (34%), Gaps = 19/165 (12%)
Query 320 ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIA 379
T+ + S S L+ + + + +GTS ++P AG A
Sbjct 574 YTEDKMSDFTSYGPVSNLSFKPDITAPGGN--IWSTQNNNGYTNMSGTSMASPFIAGSQA 631
Query 380 LTLEA-----------NKNLTWRDMQHLV--VQTSKPAHLNANDWATNGVGRKVSHSYGY 426
L +A K L + + V+ + +N ++ V + G
Sbjct 632 LLKQALNNKNNPFYAYYKQLKGTALTDFLKTVEMNTAQPINDINYNNVIVSPR---RQGA 688
Query 427 GLLDAGAMVA-LAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKT 470
GL+D A + L +N +TV + L + K ++ T
Sbjct 689 GLVDVKAAIDALEKNPSTVVAENGYPAVELKDFTSTDKTFKLTFT 733
>sp|P15292|P3P_LACLS PIII-type proteinase OS=Lactococcus lactis
subsp. cremoris (strain SK11) OX=272622 GN=prtP PE=1 SV=2
Length=1962
Score = 94.9 bits (234), Expect = 2e-18, Method: Composition-based stats.
Identities = 56/277 (20%), Positives = 93/277 (34%), Gaps = 57/277 (21%)
Query 133 NVKAAWAQ-GYTGHGIVVSILDDGIEKNHPDLA-----------------------GNY- 167
NV+A W+ Y G G VVS++D GI+ H D+ G Y
Sbjct 196 NVQAVWSNYKYKGEGTVVSVIDSGIDPTHKDMRLSDDKDVKLTKSDVEKFTDTAKHGRYF 255
Query 168 DPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVC------GVGVAYNARI 221
+ + N D + D +HG AG + A NG VGVA A++
Sbjct 256 NSKVPYGFNYADNN-DTITDDTVDEQHGMHVAGIIGA---NGTGDDPAKSVVGVAPEAQL 311
Query 222 GGVRMLDGEVTDAV--EARSLGLNPN----HIHIYSASWGPEDDGKTVDGPARLAEEAFF 275
+++ T A A + + + + S G + +T++ P
Sbjct 312 LAMKVFTNSDTSATTGSATLVSAIEDSAKIGADVLNMSLGSDSGNQTLEDP--------E 363
Query 276 RGVSQGRGGLGSIFVWASGNGGREHD-----SCNCDGYTNSIYTLSISSATQFGNVPWYS 330
Q G+ V ++GN G + + G ++ S ++ V
Sbjct 364 LAAVQNANESGTAAVISAGNSGTSGSATEGVNKDYYGLQDNEMVGSPGTSRGATTVASAE 423
Query 331 EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGT 367
T A T + G + T L + TG+
Sbjct 424 NTDVITQAVTITDGTGLQLGPETIQL---SSHDFTGS 457
Score = 37.9 bits (86), Expect = 0.46, Method: Composition-based stats.
Identities = 30/165 (18%), Positives = 56/165 (34%), Gaps = 19/165 (12%)
Query 320 ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIA 379
T+ + S S L+ + + + +GTS ++P AG A
Sbjct 574 YTEDKMSDFTSYGPVSNLSFKPDITAPGGN--IWSTQNNNGYTNMSGTSMASPFIAGSQA 631
Query 380 LTLEA-----------NKNLTWRDMQHLV--VQTSKPAHLNANDWATNGVGRKVSHSYGY 426
L +A K L + + V+ + +N ++ V + G
Sbjct 632 LLKQALNNKNNPFYAYYKQLKGTALTDFLKTVEMNTAQPINDINYNNVIVSPR---RQGA 688
Query 427 GLLDAGAMVA-LAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKT 470
GL+D A + L +N +TV + L + K ++ T
Sbjct 689 GLVDVKAAIDALEKNPSTVVAENGYPAVELKDFTSTDKTFKLTFT 733
>sp|Q9JXM7|NALP_NEIMB Neisserial autotransporter lipoprotein NalP
OS=Neisseria meningitidis serogroup B (strain MC58) OX=122586
GN=nalP PE=1 SV=1
Length=1082
Score = 94.1 bits (232), Expect = 3e-18, Method: Composition-based stats.
Identities = 70/381 (18%), Positives = 128/381 (34%), Gaps = 90/381 (24%)
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIE---KNHPDLAG-----------NY---------- 167
+N+K A GYTG G+ V I+D G + P+L G NY
Sbjct 117 INLKPAIEAGYTGRGVEVGIVDTGESVGSISFPELYGRKEHGYNENYKNYTAYMRKEAPE 176
Query 168 -----DPGASFD---VNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNA 219
D ASFD V + + P + + H + + + +G G+A +A
Sbjct 177 DGGGKDIEASFDDEAVIETEAKPTD-IRHVKEIGHIDLVSHIIGGRSVDGRPAGGIAPDA 235
Query 220 RIGGVRMLDGEVTDAVEARS----LGLNPNHIHIYSASWGPEDDGKT------------- 262
+ + D + + A + L + I + S+G T
Sbjct 236 TLHIMNTNDETKNEMMVAAIRNAWVKLGERGVRIVNNSFGTTSRAGTADLFQIANSEEQY 295
Query 263 ------------VDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNC----- 305
D RL +++ + +S +F++++GN + +
Sbjct 296 RQALLDYSGGDKTDEGIRLMQQSDYGNLSYHIRNKNMLFIFSTGNDAQAQPNTYALLPFY 355
Query 306 --DGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTES 363
D I + + + Y E + L Y S + + + +
Sbjct 356 EKDAQKGIITVAGVDRSGEKFKREMYGEPGTEPLE--YGSNHCGITAMWCLSAPYEASVR 413
Query 364 HT--------GTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNG 415
T GTS SAP+ G AL L+ ++ +++ ++ T++
Sbjct 414 FTRTNPIQIAGTSFSAPIVTGTAALLLQKYPWMSNDNLRTTLLTTAQDIGAVG------- 466
Query 416 VGRKVSHSYGYGLLDAGAMVA 436
V +G+GLLDAG +
Sbjct 467 ----VDSKFGWGLLDAGKAMN 483
>sp|Q02470|P2P_LACPA PII-type proteinase OS=Lacticaseibacillus
paracasei OX=1597 GN=prtP PE=1 SV=1
Length=1902
Score = 93.7 bits (231), Expect = 4e-18, Method: Composition-based stats.
Identities = 54/277 (19%), Positives = 92/277 (33%), Gaps = 57/277 (21%)
Query 133 NVKAAWAQ-GYTGHGIVVSILDDGIEKNHPDLA-----------------------GNY- 167
NV+A W+ Y G G VVS++D GI+ H D+ G Y
Sbjct 196 NVQAVWSNYKYKGEGTVVSVIDTGIDPTHKDMRLSDDKDVKLTKYDVEKFTDTAKHGRYF 255
Query 168 DPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVC------GVGVAYNARI 221
+ N D + D +HG AG + A NG VGVA A++
Sbjct 256 TSKVPYGFNYADNN-DTITDDTVDEQHGMHVAGIIGA---NGTGDDPTKSVVGVAPEAQL 311
Query 222 GGVRMLDGEVTDAV--EARSLGLNPN----HIHIYSASWGPEDDGKTVDGPARLAEEAFF 275
+++ T A A + + + + S G + +T++ P
Sbjct 312 LAMKVFTNSDTSATTGSATLVSAIEDSAKIGADVLNMSLGSDSGNQTLEDP--------E 363
Query 276 RGVSQGRGGLGSIFVWASGNGGREHD-----SCNCDGYTNSIYTLSISSATQFGNVPWYS 330
Q G+ V ++GN G + + G ++ + ++ V
Sbjct 364 IAAVQNANESGTAAVISAGNSGTSGSATQGVNKDYYGLQDNEMVGTPGTSRGATTVASAE 423
Query 331 EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGT 367
+ A T + G + T L + TG+
Sbjct 424 NTDVISQAVTITDGKDLQLGPETIQL---SSNDFTGS 457
Score = 39.4 bits (90), Expect = 0.17, Method: Composition-based stats.
Identities = 31/165 (19%), Positives = 57/165 (35%), Gaps = 19/165 (12%)
Query 320 ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIA 379
T+ + S S L+ + + + +GTS ++P AG A
Sbjct 574 YTEDKMSDFTSYGPVSNLSFKPDITAPGGN--IWSTQNNNGYTNMSGTSMASPFIAGSQA 631
Query 380 LTLEA---NKNLTWRDMQHL----------VVQTSKPAHLNANDWATNGVGRKVSHSYGY 426
L +A N + D + L V+ + +N ++ V + G
Sbjct 632 LLKQALNNKNNPFYADYKQLKGTALTDFLKTVEMNTAQPINDINYNNVIVSPR---RQGA 688
Query 427 GLLDAGAMVA-LAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKT 470
GL+D A + L +N +TV + L + K ++ T
Sbjct 689 GLVDVKAAIDALEKNPSTVVAENGYPAVELKDFTSTDKTFKLTFT 733
>sp|I6YC58|MYCP4_MYCTU Mycosin-4 OS=Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv) OX=83332 GN=mycP4 PE=2 SV=1
Length=455
Score = 90.6 bits (223), Expect = 8e-18, Method: Composition-based stats.
Identities = 62/362 (17%), Positives = 108/362 (30%), Gaps = 54/362 (15%)
Query 134 VKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNR 193
+ W G G V+++D G+ + H L G + + +
Sbjct 80 LDQVWRLT-RGAGQRVAVIDTGVAR-HRRL-PKVVAGGDYVFTG--------DGTADCDA 128
Query 194 HGTRCAGEVAAVAN-NGVCGVGVAYNARIGGVR--------MLDGEVTDAVEARSLGLNP 244
HGT AG +AA + GVA + + +R + D T + ++
Sbjct 129 HGTLVAGIIAAAPDAQSDNFSGVAPDVTLISIRQSSSKFAPVGDPSSTGVGDVDTMAKAV 188
Query 245 NHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASG------NGGR 298
AS V A + A ++ ++ V A+G
Sbjct 189 RTAADLGASVINISSIACVPAAAAPDDRALGAALAYAVDVKNAVIVAAAGNTGGAAQCPP 248
Query 299 EHDSCNCDGYTNSI-------YTLSISSATQFGNVPWYSEACSSTLATTYS----SGNQN 347
+ D T ++ Y L++ S G ++ A S +
Sbjct 249 QAPGVTRDSVTVAVSPAWYDDYVLTVGSVNAQGEPSAFTLAGPWVDVAATGEAVTSLSPF 308
Query 348 EKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN 407
V Q + +GTS +AP+ +G+ AL LT R + + T+
Sbjct 309 GDGTVNRLGGQHGSIPISGTSYAAPVVSGLAALIRARFPTLTARQVMQRIESTAHHPPA- 367
Query 408 ANDWATNGVGRKVSHSYGYGLLDAGAMV-----ALAQNWTTVAPQRKCIIDILTEPKDIG 462
G G +DA A V A T+ + + P
Sbjct 368 -----------GWDPLVGNGTVDALAAVSSDSIPQAGTATSDPAPVAVPVPRRSTPGPSD 416
Query 463 KR 464
+R
Sbjct 417 RR 418
>sp|O05461|MYCP1_MYCTU Mycosin-1 OS=Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv) OX=83332 GN=mycP1 PE=1 SV=1
Length=446
Score = 89.1 bits (219), Expect = 3e-17, Method: Composition-based stats.
Identities = 80/429 (19%), Positives = 128/429 (30%), Gaps = 81/429 (19%)
Query 91 PQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVS 150
P V +Q +R P W + L V A TG G+ V+
Sbjct 34 PDVTGPDQPTEQRVLCASPTTLPGSGFHDPPW-----SNTYLGVADAHKFA-TGAGVTVA 87
Query 151 ILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGV 210
++D G++ + D DQ + + + HGT A +A
Sbjct 88 VIDTGVDAS-----PRVPAEPGGDFVDQAGNGL-----SDCDAHGTLTASIIAGRPAPTD 137
Query 211 CGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARL- 269
VGVA +AR+ +R + ++A E NPN + A+ + V A L
Sbjct 138 GFVGVAPDARLLSLR----QTSEAFEPVGSQANPNDPNATPAAGSIRSLARAVVHAANLG 193
Query 270 -----AEEAFFRGVSQGRG--GLGSIF---------------VWASGNG---GREHDSCN 304
EA VS+ LG+ G+ S
Sbjct 194 VGVINISEAACYKVSRPIDETSLGASIDYAVNVKGVVVVVAAGNTGGDCVQNPAPDPSTP 253
Query 305 CD--GYTNSIY----------TLSISSATQFGNVPWYSEACSSTLATTYSS-----GNQN 347
D G+ N LS+ Q G +S + G+
Sbjct 254 GDPRGWNNVQTVVTPAWYAPLVLSVGGIGQTGMPSSFSMHGPWVDVAAPAENIVALGDTG 313
Query 348 EKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN 407
E GTS +A +G+ AL + +LT + H + T++
Sbjct 314 EPVNALQGREGP--VPIAGTSFAAAYVSGLAALLRQRFPDLTPAQIIHRITATARH---- 367
Query 408 ANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEV 467
G V G G++DA A W ++ P + +
Sbjct 368 --------PGGGVDDLVGAGVIDA----VAALTWDIPPGPASAPYNVRRLPPPVVEPGPD 415
Query 468 RKTVTACLG 476
R+ +TA
Sbjct 416 RRPITAVAL 424
>sp|Q6ESI7|TPPII_ORYSJ Tripeptidyl-peptidase 2 OS=Oryza sativa
subsp. japonica OX=39947 GN=TPP2 PE=2 SV=1
Length=1359
Score = 89.9 bits (221), Expect = 5e-17, Method: Composition-based stats.
Identities = 61/321 (19%), Positives = 103/321 (32%), Gaps = 54/321 (17%)
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD--- 228
SF N D D + + H T AG AA + GVA A++ ++ D
Sbjct 332 SFVANIYD-DGNLVSIVTDCSPHATHVAGIAAAFHPDEPLLNGVAPGAQLISCKIGDTRL 390
Query 229 ---GEVTDAVEARSLGLNPNHIHIYSASWGP----EDDGKTVDGPARLAEEAFFRGVSQG 281
T V A + + + + S+G D G+ +D + + ++
Sbjct 391 GSMETGTGLVRALIAAVE-HKCDLINMSYGEPTLLPDYGRFIDLASEVVDKHR------- 442
Query 282 RGGLGSIFVWASGNGGREHDSCNCDGYTNS--IYTLS-------------ISSATQFGNV 326
IF+ ++GN G ++ G T+S I + + + +
Sbjct 443 -----IIFISSAGNNGPALNTVGAPGGTSSSIIGVGAYVSPAMAAGAHCVVQAPAEGMEY 497
Query 327 PWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANK 386
W S ++ S + GTS S+P A G +AL + A K
Sbjct 498 TWSSRGPTADGDLGVSISAPGGAVAPVPTWTLQSRMLMNGTSMSSPSACGGVALLVSAMK 557
Query 387 N----LTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWT 442
L+ ++ + T+ + T G+GLL AQ
Sbjct 558 AEGIPLSPYTVRKAIENTAASISDVPEEKLTT----------GHGLLQVDRAFEYAQQAK 607
Query 443 TVAPQRKCIIDILTEPKDIGK 463
+ P I I K K
Sbjct 608 EL-PLVSYRISINQVGKPTSK 627
>sp|F4JVN6|TPPII_ARATH Tripeptidyl-peptidase 2 OS=Arabidopsis
thaliana OX=3702 GN=TPP2 PE=1 SV=1
Length=1380
Score = 87.9 bits (216), Expect = 2e-16, Method: Composition-based stats.
Identities = 64/319 (20%), Positives = 97/319 (30%), Gaps = 46/319 (14%)
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG-- 229
SF N D + + + + HGT AG A GVA A+I ++ D
Sbjct 351 SFVANVYD-EGKVLSIVTDSSPHGTHVAGIATAHHPEEHLLNGVAPGAQIISCKIGDSRL 409
Query 230 ----EVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGL 285
T A L N + + S+G L EA
Sbjct 410 GSMETGTGLTRALIAALEHN-CDLVNMSYGEPALLPDYGRFVDLVTEAV--------NKR 460
Query 286 GSIFVWASGNGGREHDSCNCDGYTNS------IYTLSISSATQFGNVPWYSEACSSTLAT 339
IFV ++GN G + G T S Y +A V SE T ++
Sbjct 461 RLIFVSSAGNSGPALTTVGAPGGTTSSIIGVGAYVSPAMAAGAHSVVEPPSEGLEYTWSS 520
Query 340 TYSSGNQNEKQIVT---------TDLRQKCTESHTGTSASAPLAAGIIALTLEANKN--- 387
+ + + ++ + GTS ++P A G IAL L A K
Sbjct 521 RGPTSDGDLGVCISAPGGAVAPVPTWTLQRRMLMNGTSMASPSACGAIALLLSAMKAEGI 580
Query 388 -LTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAP 446
++ ++ + TS P D T G GL+ + + P
Sbjct 581 PVSPYSVRRALENTSTPVGDLPEDKLTT----------GQGLMQVDKAYEYLKQFQDY-P 629
Query 447 QRKCIIDILTEPKDIGKRL 465
I + K I
Sbjct 630 CVFYQIKVNLSGKTIPTSR 648
>sp|P29144|TPP2_HUMAN Tripeptidyl-peptidase 2 OS=Homo sapiens
OX=9606 GN=TPP2 PE=1 SV=4
Length=1249
Score = 84.5 bits (207), Expect = 2e-15, Method: Composition-based stats.
Identities = 52/259 (20%), Positives = 87/259 (34%), Gaps = 36/259 (14%)
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD--- 228
++ VN D D + HGT A A GVA A+I +++ D
Sbjct 243 NYSVNIYD-DGNLLSIVTSGGAHGTHVASIAAGHFPEEPERNGVAPGAQILSIKIGDTRL 301
Query 229 ---GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGL 285
T + A +N + + + S+G + R+ E +++
Sbjct 302 STMETGTGLIRAMIEVIN-HKCDLVNYSYG---EATHWPNSGRICE-----VINEAVWKH 352
Query 286 GSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA---------------TQFGNVPWYS 330
I+V ++GN G + C G T S + + + W S
Sbjct 353 NIIYVSSAGNNGPCLSTVGCPGGTTS-SVIGVGAYVSPDMMVAEYSLREKLPANQYTWSS 411
Query 331 EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA----NK 386
S+ A S + + T+ GTS S+P A G IAL L N
Sbjct 412 RGPSADGALGVSISAPGGAIASVPNWTLRGTQLMNGTSMSSPNACGGIALILSGLKANNI 471
Query 387 NLTWRDMQHLVVQTSKPAH 405
+ T ++ + T+ A
Sbjct 472 DYTVHSVRRALENTAVKAD 490
>sp|A9QY38|SBT4_LOTJA Subtilisin-like protease 4 OS=Lotus japonicus
OX=34305 GN=SBTM4 PE=2 SV=1
Length=755
Score = 84.1 bits (206), Expect = 2e-15, Method: Composition-based stats.
Identities = 44/289 (15%), Positives = 92/289 (32%), Gaps = 70/289 (24%)
Query 67 FWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSG 126
+ +T+ LS ++ + PQ + L +Q + Q+
Sbjct 90 GFAASLTQEELSAVEKKNGFISAHPQ-RVLHRQTTHTPKFLGLQQD-------------- 134
Query 127 VTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG--------------------- 165
W + G G+++ +LD GI HP +
Sbjct 135 --------TGVWKESNFGKGVIIGVLDSGITPGHPSFSDVGIPPPPPKWKGRCDLNVTAC 186
Query 166 --NYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA-------VANNGVCG-VGV 215
+F++ + + + ++++ HGT A A V N G+
Sbjct 187 NNKLIGARAFNLAAEAMNGKKAEAPIDEDGHGTHTASTAAGAFVNYAEVLGNAKGTAAGM 246
Query 216 AYNARIGGVRML---DGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEE 272
A +A + ++ D +D + A + + + + S S G + P +
Sbjct 247 APHAHLAIYKVCFGEDCPESDILAALDAAVE-DGVDVISISLG-------LSEPPPFFND 298
Query 273 AFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
+ G G A+GN G + S + + L++ ++T
Sbjct 299 STAIGAFAAMQ-KGIFVSCAAGNSGPFNSSI----VNAAPWILTVGAST 342
Score = 40.6 bits (93), Expect = 0.058, Method: Composition-based stats.
Identities = 10/42 (24%), Positives = 23/42 (55%), Gaps = 0/42 (0%)
Query 365 TGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHL 406
+GTS S P +GI AL ++ + + ++ ++ ++ +L
Sbjct 541 SGTSMSCPHLSGIAALLKSSHPHWSPAAIKSAIMTSADTINL 582
>sp|Q64560|TPP2_RAT Tripeptidyl-peptidase 2 OS=Rattus norvegicus
OX=10116 GN=Tpp2 PE=2 SV=3
Length=1249
Score = 84.1 bits (206), Expect = 3e-15, Method: Composition-based stats.
Identities = 52/259 (20%), Positives = 88/259 (34%), Gaps = 36/259 (14%)
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD--- 228
++ VN D D + HGT A A GVA A+I +++ D
Sbjct 243 NYSVNIYD-DGNLLSIVTSGGAHGTHVASIAAGHFPEEPERNGVAPGAQILSIKIGDTRL 301
Query 229 ---GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGL 285
T + A +N + + + S+G + R+ E +++
Sbjct 302 STMETGTGLIRAMIEVIN-HKCDLVNYSYG---EATHWPNSGRICE-----VINEAVWKH 352
Query 286 GSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA---------------TQFGNVPWYS 330
+I+V ++GN G + C G T S + + + W S
Sbjct 353 NTIYVSSAGNNGPCLSTVGCPGGTTS-SVIGVGAYVSPDMMVAEYSLREKLPANQYTWSS 411
Query 331 EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA----NK 386
S+ A S + + T+ GTS S+P A G IAL L N
Sbjct 412 RGPSADGALGVSISAPGGAIASVPNWTLRGTQLMNGTSMSSPNACGGIALVLSGLKANNV 471
Query 387 NLTWRDMQHLVVQTSKPAH 405
+ T ++ + T+ A
Sbjct 472 DYTVHSVRRALENTAIKAD 490
>sp|Q64514|TPP2_MOUSE Tripeptidyl-peptidase 2 OS=Mus musculus
OX=10090 GN=Tpp2 PE=1 SV=3
Length=1262
Score = 84.1 bits (206), Expect = 3e-15, Method: Composition-based stats.
Identities = 52/259 (20%), Positives = 88/259 (34%), Gaps = 36/259 (14%)
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD--- 228
++ VN D D + HGT A A GVA A+I +++ D
Sbjct 243 NYSVNIYD-DGNLLSIVTSGGAHGTHVASIAAGHFPEEPERNGVAPGAQILSIKIGDTRL 301
Query 229 ---GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGL 285
T + A +N + + + S+G + R+ E +++
Sbjct 302 STMETGTGLIRAMIEVIN-HKCDLVNYSYG---EATHWPNSGRICE-----VINEAVWKH 352
Query 286 GSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA---------------TQFGNVPWYS 330
+I+V ++GN G + C G T S + + + W S
Sbjct 353 NTIYVSSAGNNGPCLSTVGCPGGTTS-SVIGVGAYVSPDMMVAEYSLREKLPANQYTWSS 411
Query 331 EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEA----NK 386
S+ A S + + T+ GTS S+P A G IAL L N
Sbjct 412 RGPSADGALGVSISAPGGAIASVPNWTLRGTQLMNGTSMSSPNACGGIALVLSGLKANNV 471
Query 387 NLTWRDMQHLVVQTSKPAH 405
+ T ++ + T+ A
Sbjct 472 DYTVHSVRRALENTAIKAD 490
>sp|A5PK39|TPP2_BOVIN Tripeptidyl-peptidase 2 OS=Bos taurus OX=9913
GN=TPP2 PE=2 SV=1
Length=1249
Score = 83.7 bits (205), Expect = 4e-15, Method: Composition-based stats.
Identities = 53/259 (20%), Positives = 87/259 (34%), Gaps = 36/259 (14%)
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLD--- 228
++ VN D D + HGT A A GVA A+I +++ D
Sbjct 243 NYSVNIYD-DGNLLSIVTSGGAHGTHVASIAAGHFPEEPERNGVAPGAQILSIKIGDTRL 301
Query 229 ---GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGL 285
T + A +N + + + S+G + R+ E +++
Sbjct 302 STMETGTGLIRAMIEVIN-HKCDLVNYSYG---EATHWPNSGRICE-----VINEAVWKH 352
Query 286 GSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA---------------TQFGNVPWYS 330
I+V ++GN G + C G T S + + + W S
Sbjct 353 NIIYVSSAGNNGPCLSTVGCPGGTTS-SVIGVGAYVSPDMMVAEYSLREKLPANQYTWSS 411
Query 331 EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANK---- 386
S+ A S + + T+ GTS S+P A G IAL L K
Sbjct 412 RGPSADGALGVSVSAPGGAIASVPNWTLRGTQLMNGTSMSSPNACGGIALVLSGLKANDV 471
Query 387 NLTWRDMQHLVVQTSKPAH 405
N T ++ + T+ A
Sbjct 472 NYTVHSVRRALENTAVKAD 490
>sp|Q09541|TPP2_CAEEL Tripeptidyl-peptidase 2 OS=Caenorhabditis
elegans OX=6239 GN=tpp-2 PE=2 SV=1
Length=1374
Score = 82.9 bits (203), Expect = 8e-15, Method: Composition-based stats.
Identities = 49/246 (20%), Positives = 85/246 (35%), Gaps = 33/246 (13%)
Query 180 PDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARS 239
PD + HG+ AG AA + G+A A+I + + D + ++
Sbjct 300 PDGNLTEIVVPSGAHGSHVAGIAAANYPDNPQKNGLAPGAKILSLNIGDHRLGAMETGQA 359
Query 240 LGLNPN-----HIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASG 294
+ N ++ I + S+G +G + R+ EEA + G I+V ++G
Sbjct 360 MTRAFNMCAELNVDIINMSFG---EGTHLPDVGRVIEEA-----RRLINRRGVIYVCSAG 411
Query 295 NGGREHDSCNCDGYTNSIYTLSISSAT---------------QFGNVPWYSEACSSTLAT 339
N G + G T + + I + + PW S
Sbjct 412 NQGPALSTVGAPGGTTT-GVIGIGAYLTSESADTLYGVYKPVESSIYPWSSRGPCQDGKL 470
Query 340 TYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE--ANKNLTWR--DMQH 395
S ++ + GTS S+P AAG +A L NL W ++
Sbjct 471 GVSLVAPAAAFAGVPQYCRQSMQMMNGTSMSSPNAAGNVACMLSGLKQNNLKWTPYTVRM 530
Query 396 LVVQTS 401
+ T+
Sbjct 531 ALENTA 536
>sp|P31631|SSA1_MANHA Serotype-specific antigen 1 OS=Mannheimia
haemolytica OX=75985 GN=ssa1 PE=1 SV=1
Length=932
Score = 81.0 bits (198), Expect = 2e-14, Method: Composition-based stats.
Identities = 66/373 (18%), Positives = 123/373 (33%), Gaps = 89/373 (24%)
Query 142 YTGHGIVVSILDDGIEKNHPDLAGNYDPG---------------ASFDVNDQDPDPQPRY 186
Y+G G+ + ++D+G HP + + P AS+ + +P +
Sbjct 47 YSGKGVKLGVMDEGFMVKHPRHSSHLHPLIHQLTTPEGEVRIYDASYPQFEVNPVEKEDG 106
Query 187 TQM--NDNRHGTRCAGEVAAVANNGVC---GVGVAYNARIGGV-----RMLDGEVTDAVE 236
+ + HG AG +AA A+ + G+A A + R L+ + DA +
Sbjct 107 IDLIPSLETHGAGVAGIIAAQADKTLGDGYSGGIAKGAELYVATKSYKRTLEKVIQDAKK 166
Query 237 A-------------------------------------RSLGLN---PNHIHIYSASWGP 256
+ GLN N++ + SW P
Sbjct 167 ELENAKDEEDEKTPSLDQMAKNDLLASKEKEMAIERAEWASGLNKLLDNNVFAINNSWNP 226
Query 257 ---EDDGKTVDGPARLAEEAFFRGVSQG---RGGLGSIFVWASGNGGREHDSCNC---DG 307
DD VD + ++ + Q ++ V+A+GN ++
Sbjct 227 FSISDDINVVDKFYQSIKQNKHNPLLQAIMRAKNSNTLLVFAAGNESKKQPGVMALLPRY 286
Query 308 YTNSIYT-LSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHT- 365
+ +S + + + YS C ++ ++ I D +K T
Sbjct 287 FPELEKNLISAVAVDKEQKIASYSNHCGASKNWCVAAPGDLHVLIGVADEHKKPQYGLTK 346
Query 366 --GTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHS 423
GTS SAP +A+ E LT ++ ++ T+ V +
Sbjct 347 EQGTSFSAPAITASLAVLKERFDYLTATQIRDTLLTTATDLGEKG-----------VDNV 395
Query 424 YGYGLLDAGAMVA 436
YG+GL++ V
Sbjct 396 YGWGLINLKKAVN 408
>sp|P81719|PIIS_ACHLY Protease 2 small chain (Fragment) OS=Achromobacter
lyticus OX=224 PE=1 SV=1
Length=63
Score = 69.8 bits (169), Expect = 1e-13, Method: Composition-based stats.
Identities = 24/63 (38%), Positives = 33/63 (52%), Gaps = 3/63 (5%)
Query 113 PTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS 172
P DP + QQW LSG + AW GY G G +++++D GI +HPDL N
Sbjct 3 PNDPLYSQQWGLSGT--YGIRANTAWDNGYQGQGKIIAVVDTGI-TDHPDLLANRTSPLG 59
Query 173 FDV 175
+D
Sbjct 60 YDF 62
>sp|Q9UT05|TPP2_SCHPO Tripeptidyl-peptidase 2 homolog OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=tpp2
PE=1 SV=1
Length=1274
Score = 78.7 bits (192), Expect = 1e-13, Method: Composition-based stats.
Identities = 61/313 (19%), Positives = 103/313 (33%), Gaps = 51/313 (16%)
Query 151 ILD---DGIEKNHPDLAG-NYDPGASFDVNDQDPDPQPRYTQMNDN---------RHGTR 197
++D G H LA N S D + N N HGT
Sbjct 271 VIDSDQTGDIYLHKPLADFNVAQEWS-TFGSLDLLSYGVHVYDNGNITSIVAVSGTHGTH 329
Query 198 CAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEV-----TDAVEARSLGLNPNHIHIYSA 252
AG + A G A ++ + + DG + + A + N + I +
Sbjct 330 VAGIIGANHPETPELNGAAPGCQLVSLMIGDGRLDSLETSHAFSRACSEIIKNEVDIINI 389
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
S+G + L + + G + V ++GN G + + G T +
Sbjct 390 SFGEDAGIPNKGRVIELLRD-------ELAGKRNVVIVSSAGNNGPAYTTVGAPGGT-TF 441
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYS--------------SGNQNEKQIVTTDLRQ 358
+S+ + G + S+ T Y+ S I +
Sbjct 442 DVISVGAYVTSGMMQAQYNLLSTVHDTPYTWCSRGPTLDGDTGVSIYAPGGAITSVPPYS 501
Query 359 -KCTESHTGTSASAPLAAGIIALTLEA----NKNLTWRDMQHLVVQTSKPAHLNANDWAT 413
+ ++ GTS S+P A G I+L L A K T ++ V+ TSK +
Sbjct 502 LQNSQLMNGTSMSSPSACGGISLILSALKAQKKPYTAAAIKKAVMYTSKDLRDD-----F 556
Query 414 NGVGRKVSHSYGY 426
N +V ++Y Y
Sbjct 557 NTGMLQVDNAYEY 569
>sp|O64495|SBT12_ARATH Subtilisin-like protease SBT1.2 OS=Arabidopsis
thaliana OX=3702 GN=SBT1.2 PE=2 SV=1
Length=775
Score = 76.4 bits (186), Expect = 6e-13, Method: Composition-based stats.
Identities = 61/375 (16%), Positives = 109/375 (29%), Gaps = 69/375 (18%)
Query 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI 60
ME +P+ L + + LL + + + T+ V++ A + A K +
Sbjct 1 MEPKPFFLCI------IFLLFCSSSSEILQKQTYIVQLHPNSETAKTFASKFDWHL--SF 52
Query 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
+ + S S ++ + R + V P Q
Sbjct 53 LQEAVLGVEEEEEEPSSRLLYSYGSAIEGFAAQLTESEAEILRYSPEVVAVRPDHVLQVQ 112
Query 121 QWYLSGVTQRD-LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDP---------- 169
Y D W++ G G ++ +LD G+ P P
Sbjct 113 TTYSYKFLGLDGFGNSGVWSKSRFGQGTIIGVLDTGVWPESPSFDDTGMPSIPRKWKGIC 172
Query 170 --GASFDVNDQD-----------------------PDPQPRYTQMNDNRHGTRCAGEV-- 202
G SF + + P+ + + HGT A V
Sbjct 173 QEGESFSSSSCNRKLIGARFFIRGHRVANSPEESPNMPREYISARDSTGHGTHTASTVGG 232
Query 203 -----AAVANNGVCGV-GVAYNARIGGVRM---LDGEVTDAVEARSLGLNPNHIHIYSAS 253
A V NG G+A A I ++ +D + A + + + + + S S
Sbjct 233 SSVSMANVLGNGAGVARGMAPGAHIAVYKVCWFNGCYSSDILAAIDVAI-QDKVDVLSLS 291
Query 254 WGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIY 313
G P L ++ G + G + A+GN G S + +
Sbjct 292 LG--------GFPIPLYDDTIAIGTFRAMER-GISVICAAGNNGPIESSVAN----TAPW 338
Query 314 TLSISSATQFGNVPW 328
+I + T P
Sbjct 339 VSTIGAGTLDRRFPA 353
Score = 43.3 bits (100), Expect = 0.009, Method: Composition-based stats.
Identities = 16/75 (21%), Positives = 29/75 (39%), Gaps = 5/75 (7%)
Query 364 HTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHS 423
+GTS S P +GI AL A N + ++ ++ T+ G K +
Sbjct 548 MSGTSMSCPHVSGITALIRSAYPNWSPAAIKSALMTTADLYDRQGKAIKD---GNKPAGV 604
Query 424 Y--GYGLLDAGAMVA 436
+ G G ++ +
Sbjct 605 FAIGAGHVNPQKAIN 619
>sp|Q80T14|FRAS1_MOUSE Extracellular matrix organizing protein
FRAS1 OS=Mus musculus OX=10090 GN=Fras1 PE=1 SV=2
Length=4010
Score = 75.2 bits (183), Expect = 2e-12, Method: Composition-based stats.
Identities = 29/100 (29%), Positives = 38/100 (38%), Gaps = 20/100 (20%)
Query 586 GCKTLT--SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
C T S C CE +L CV CP +TH++ E C
Sbjct 716 SCLTCEGKSPHNCTGCESTHALLAGCCVSQCP--------ETHFNLEGT--------CTE 759
Query 644 CHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
CH SC C GP +DC+SC H +L C + +
Sbjct 760 CHPSCRQCHGPLESDCVSCHPHLTL--TSGHCKTSCKEEQ 797
Score = 59.8 bits (143), Expect = 1e-07, Method: Composition-based stats.
Identities = 28/106 (26%), Positives = 39/106 (37%), Gaps = 20/106 (19%)
Query 579 PVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRA 638
P P + CK + V G ++ CV C TH+ E+
Sbjct 664 PQPSHCTQCKKPE-AGLLVEQHSGENVPYGKCVSRC---------GTHFYLEST------ 707
Query 639 SVCAPCHASCATCQGPALTDCLSCPS-HASLDPVEQTCSRQSQSSR 683
+C CH SC TC+G + +C C S HA L C Q +
Sbjct 708 GLCEVCHPSCLTCEGKSPHNCTGCESTHALLAGC---CVSQCPETH 750
Score = 59.1 bits (141), Expect = 2e-07, Method: Composition-based stats.
Identities = 30/125 (24%), Positives = 41/125 (33%), Gaps = 34/125 (27%)
Query 584 SSGCKTLT-SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDV--------- 633
CK+ SS C+ C E LH C+ CP G+ + +
Sbjct 561 DQSCKSCGPSSPRCLSCAEKTILHDGKCISECPHGYYADSTGSCKVCHSSCASCSGPTAA 620
Query 634 --------ETIRASVCAP---------------CHASCATCQGPALTDCLSC-PSHASLD 669
+T+R C P CHASC TC GP + C C A L
Sbjct 621 HCIACIHPQTLRQGHCLPSCGEGFYPDHGICEACHASCHTCVGPQPSHCTQCKKPEAGLL 680
Query 670 PVEQT 674
+ +
Sbjct 681 VEQHS 685
Score = 55.2 bits (131), Expect = 3e-06, Method: Composition-based stats.
Identities = 22/110 (20%), Positives = 34/110 (31%), Gaps = 18/110 (16%)
Query 576 EGLPVPPESSGCKTLTSSQACVVCEEGFSLH--QKSCVQHCPPGFAPQVLDTHYSTENDV 633
+ P + C++ S +C C + + + + C P + +
Sbjct 901 DNQVCQPCNRHCRSCDSQGSCTSCRDPSKVLLFGECQYESCTPQYYLDIAT--------- 951
Query 634 ETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
C C SC C GP TDCL C L + C Q
Sbjct 952 -----KTCKECDWSCNACTGPLRTDCLQCMDGYVL--QDGVCVEQCSPQH 994
Score = 52.5 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 30/120 (25%), Positives = 41/120 (34%), Gaps = 20/120 (17%)
Query 563 LTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQV 622
+ L Y L P+ C T T+ C C + Q CV C GF
Sbjct 450 VHSCGLGFYQAGSLCLACQPQ---CSTCTNGLECSSCLPPLLMQQGQCVSTCGDGFYQD- 505
Query 623 LDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
H+S CA CH SCA C GP C++C + + +C +
Sbjct 506 ---HHS------------CAVCHESCAGCWGPTEKHCMACRDPLQV-LRDSSCENTCGNG 549
Score = 51.7 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 27/104 (26%), Positives = 33/104 (32%), Gaps = 20/104 (19%)
Query 579 PVPPESSGC--KTLTSSQACVVC-EEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVET 635
P C + C+ C L CV CPPG HY
Sbjct 807 DCHPLCQHCVANLQDTGSICLKCQHARHLLLGDHCVPECPPG--------HYKERGT--- 855
Query 636 IRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS 679
C CH+SC +CQ C SC + L + TCS
Sbjct 856 -----CKTCHSSCRSCQNGGPFSCSSCDTGLVLTHI-GTCSTAC 893
Score = 49.4 bits (116), Expect = 2e-04, Method: Composition-based stats.
Identities = 24/123 (20%), Positives = 27/123 (22%), Gaps = 18/123 (15%)
Query 576 EGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVET 635
+ S C C CEE F L Q CVQ C G+
Sbjct 997 DSGSCKRCDSHCVECQGPHECTRCEEPFLLFQAQCVQECGKGYFADHA------------ 1044
Query 636 IRASVCAPCHASCATCQGPALTDCLSCPSHASLD--PVEQTCSRQSQSSRESPPQQQPPR 693
C C C C C C L TC +
Sbjct 1045 --KHRCIACPQGCLRC--SHKDRCHLCDHSFFLKSGLCMPTCVPGFSGHSSNENCTDKMY 1100
Query 694 LPP 696
P
Sbjct 1101 TPS 1103
Score = 43.7 bits (101), Expect = 0.009, Method: Composition-based stats.
Identities = 25/121 (21%), Positives = 37/121 (31%), Gaps = 29/121 (24%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQA---------CVVCEEGFSLHQKSCVQHCPPGFAPQ 621
Y + + + CK S C+ C +G+ L CV+ C P
Sbjct 938 YESCTPQYYLDIATKTCKECDWSCNACTGPLRTDCLQCMDGYVLQDGVCVEQCSP----- 992
Query 622 VLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
HY C C + C CQGP +C C L + C ++
Sbjct 993 ---QHYRDSGS--------CKRCDSHCVECQGPH--ECTRCEEPFLL--FQAQCVQECGK 1037
Query 682 S 682
Sbjct 1038 G 1038
>sp|Q9V6K1|TPP2_DROME Tripeptidyl-peptidase 2 OS=Drosophila melanogaster
OX=7227 GN=TppII PE=1 SV=2
Length=1441
Score = 74.9 bits (182), Expect = 2e-12, Method: Composition-based stats.
Identities = 43/272 (16%), Positives = 82/272 (30%), Gaps = 50/272 (18%)
Query 194 HGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL----------GLN 243
HGT + +A+ ++ GVA NA+I + + DG + +L +
Sbjct 359 HGTHVSS-IASGNHSSRDVDGVAPNAKIVSMTIGDGRLGSMETGTALVRAMTKVMELCRD 417
Query 244 PNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSC 303
I + + S+G + L E G ++V ++GN G +
Sbjct 418 GRRIDVINMSYGEHANWSNSGRIGELMNEVV--------NKYGVVWVASAGNHGPALCTV 469
Query 304 NCDGYTNSIYTLSISSATQ----FGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQK 359
+ + + + + + T + Q VT
Sbjct 470 GTPPDISQPSLIGVGAYVSPQMMEAEYAMREKLPGNVYTWTSRDPCIDGGQGVTVCAPGG 529
Query 360 CTES-----------HTGTSASAPLAAGIIALTL----EANKNLTWRDMQHLVVQTSKPA 404
S GTS +AP AG +AL + + N + ++ + T+
Sbjct 530 AIASVPQFTMSKSQLMNGTSMAAPHVAGAVALLISGLKQQNIEYSPYSIKRAISVTATKL 589
Query 405 HLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
+ G+GLL+
Sbjct 590 GYVDP------------FAQGHGLLNVEKAFE 609
>sp|Q9SA75|SBT21_ARATH Subtilisin-like protease SBT2.1 OS=Arabidopsis
thaliana OX=3702 GN=SBT2.1 PE=2 SV=1
Length=832
Score = 74.5 bits (181), Expect = 3e-12, Method: Composition-based stats.
Identities = 47/276 (17%), Positives = 79/276 (29%), Gaps = 80/276 (29%)
Query 135 KAAWAQG----YTGHGIVVSILDDGIEKNHPDLAGNYDP--------------------- 169
+ AW + Y G G+V+ +D GI+ HP +
Sbjct 150 RGAWLRDGGSEYAGEGVVIGFIDTGIDPTHPSFSDKISGHTYSVPPHFTGVCEVTIGFPP 209
Query 170 -----------------GASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCG 212
+ +N D P + HGT A A N+G+
Sbjct 210 GSCNRKLIGARHFAESALSRGVLNSSQDDASPF----DGEGHGTHTAS--VAAGNHGIPV 263
Query 213 V----------GVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWGP-- 256
V G+A A I + L G D + A + + I + S P
Sbjct 264 VVAGHRLGNASGMAPRAHIAIYKALYKRFGGFAADIIAAIDQAA-QDGVDIINLSITPNR 322
Query 257 -EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTL 315
T P +A + + G V A+GN G S + S +
Sbjct 323 RPPGIATFFNPIDMALLSAVKA--------GIFVVQAAGNTGPAPKSM----SSFSPWIF 370
Query 316 SISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQI 351
++ + + + + T G + +I
Sbjct 371 TVGATSHD--RVYSNSIILGNNVTIPGVGLASGTRI 404
Score = 47.5 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 20/101 (20%), Positives = 33/101 (33%), Gaps = 8/101 (8%)
Query 344 GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKP 403
G + I T D + + +GTS SAP GI AL + + T + + T+
Sbjct 585 GAWSPLGIGTNDFQGERFAMESGTSMSAPHVTGIAALIKQKFPHFTPAAIASALSTTASL 644
Query 404 AHLNANDWATNGVGRKVS--------HSYGYGLLDAGAMVA 436
+ G G ++A A +
Sbjct 645 SDRKGEHIMAQRTVLNPDISQSPATPFDMGSGFVNATAALD 685
>sp|O64481|SBT25_ARATH Subtilisin-like protease SBT2.5 OS=Arabidopsis
thaliana OX=3702 GN=SBT2.5 PE=2 SV=1
Length=815
Score = 74.1 bits (180), Expect = 3e-12, Method: Composition-based stats.
Identities = 71/335 (21%), Positives = 111/335 (33%), Gaps = 87/335 (26%)
Query 45 ANSVARKHGFLNLGQIFGD-----YYHFWHRGVTKRS-LSPHRPRHSRLQREPQVQWLEQ 98
A + RKH + LG +F + Y + H + +SP + L+R P V+ +++
Sbjct 63 ARHLERKHDMI-LGMLFEEGSYKKLYSYKHLINGFAAHVSPEQAET--LRRAPGVRSVDK 119
Query 99 QVAKRRTKR---DVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDG 155
RR + PTD W G R G IV+ +D G
Sbjct 120 DWKVRRLTTHTPEFLGLPTDV-----WPTGGGFDR------------AGEDIVIGFVDSG 162
Query 156 IEKNHPDLA----------GNYDPGASFDVNDQDPD----------------------PQ 183
I +HP A +Y D + + P
Sbjct 163 IYPHHPSFASHHRLPYGPLPHYKGKCEEDPHTKKSFCNRKIVGAQHFAEAAKAAGAFNPD 222
Query 184 PRY-TQMNDNRHGTRCAGEVAAVANNGV----------CGVGVAYNARIGGVRML----D 228
Y + M+ + HG+ A A NNG+ G+A ARI + L
Sbjct 223 IDYASPMDGDGHGSHTAAI--AAGNNGIPLRMHGYEFGKASGMAPRARIAVYKALYRLFG 280
Query 229 GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
G V D V A ++ + + I S S GP T +A G + G
Sbjct 281 GFVADVVAAIDQAVH-DGVDILSLSVGPNSPPTTTKTTFLNPFDATLLGAVK----AGVF 335
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISSATQF 323
A+GNGG + S + ++++A
Sbjct 336 VAQAAGNGGPF----PKTLVSYSPWITTVAAAIDD 366
Score = 46.0 bits (107), Expect = 0.001, Method: Composition-based stats.
Identities = 22/113 (19%), Positives = 40/113 (35%), Gaps = 13/113 (12%)
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWR 391
A + + +E V + +GTS +AP AGI AL + + +
Sbjct 565 APGYLIWAAWCPNGTDEPNYV-----GEGFALISGTSMAAPHIAGIAALVKQKHPQWSPA 619
Query 392 DMQHLVVQTSKPAH-----LNANDWATNGVGRKVSH---SYGYGLLDAGAMVA 436
++ ++ TS L A ++ V YG G ++ A +
Sbjct 620 AIKSALMTTSTVIDRAGRLLQAQQYSDTEAVTLVKATPFDYGSGHVNPSAALD 672
>sp|A9QY39|SBT3_LOTJA Subtilisin-like protease 3 OS=Lotus japonicus
OX=34305 GN=SBTM3 PE=2 SV=1
Length=750
Score = 72.9 bits (177), Expect = 7e-12, Method: Composition-based stats.
Identities = 40/221 (18%), Positives = 69/221 (31%), Gaps = 55/221 (25%)
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAG------------------------NYDPGA 171
W +G G+++ ILD GI HP +
Sbjct 135 GLWKGSNSGKGVIIGILDTGISPFHPSFSDEGMPSPPAKWNGICEFTGKRTCNNKIIGAR 194
Query 172 SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA--------VANNGVCGVGVAYNARIGG 223
+F P +D HGT A A N VG+A +A I
Sbjct 195 NFVKTKNLTLPF------DDVGHGTHTASTAAGRPVQGANVYGNANGTAVGMAPDAHIAM 248
Query 224 VRMLDGEVTDAVEARSLGLNP---NHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQ 280
++ G V + A G++ + + + S S G G + P L +
Sbjct 249 YKVC-GLVGCSESAILAGMDTAVDDGVDVLSLSLGGPS-GPFFEDPIALG--------AF 298
Query 281 GRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
G G ++ N G + S + + L++ +++
Sbjct 299 GAIQKGIFVSCSAANSGPAYSS----LSNEAPWILTVGASS 335
Score = 44.0 bits (102), Expect = 0.006, Method: Composition-based stats.
Identities = 13/59 (22%), Positives = 25/59 (42%), Gaps = 3/59 (5%)
Query 353 TTDLRQKCTESH---TGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA 408
L T +GTS S P +GI AL ++ + + ++ ++ T+ +L
Sbjct 518 PVSLDNSTTPPFNIISGTSMSCPHLSGIAALLKNSHPDWSPAAIKSAIMTTASQVNLGG 576
>sp|Q9SUN6|SBT22_ARATH Subtilisin-like protease SBT2.2 OS=Arabidopsis
thaliana OX=3702 GN=SBT2.2 PE=3 SV=1
Length=856
Score = 71.8 bits (174), Expect = 1e-11, Method: Composition-based stats.
Identities = 47/243 (19%), Positives = 72/243 (30%), Gaps = 67/243 (28%)
Query 135 KAAW--AQGY--TGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQ-------DPD-- 181
K AW GY G GIV+ +D GI+ HP G + + + PD
Sbjct 171 KGAWVKEGGYETAGEGIVIGFIDTGIDPTHPSFNGTDTSQRQYPIPNHFSGVCEVTPDFP 230
Query 182 --------------------------PQPRYTQMNDNRHGTRCAGEVAA--------VAN 207
+ + + + HGT A A +
Sbjct 231 SGSCNRKLVGARHFAQSAITRGIFNSSEDYASPFDGDGHGTHTASIAAGNHGVSAVVSGH 290
Query 208 NGVCGVGVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWGP---EDDG 260
N G+A A I + L G D V A + + I S S P
Sbjct 291 NFGSASGIAPRAHISVYKALYKSFGGFAADVVAAIDQAA-QDGVDILSLSITPNRRPPGV 349
Query 261 KTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSA 320
T P +A + + G V A+GN G + S + ++ +A
Sbjct 350 ATFFNPLDMAMLSAVKA--------GIFVVQAAGNTGP----SPKSMSSFSPWIFTVGAA 397
Query 321 TQF 323
+
Sbjct 398 SHD 400
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 18/101 (18%), Positives = 35/101 (35%), Gaps = 8/101 (8%)
Query 344 GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKP 403
G + +T+ + +GTS +AP AG+ AL + + + + + TS
Sbjct 610 GAWSSAATESTEFEGESFAMMSGTSMAAPHVAGVAALVKQKFRKFSPSAIASALSTTSVL 669
Query 404 AHLNANDWATNGV----GRKVSH----SYGYGLLDAGAMVA 436
+ +S G G ++A A +
Sbjct 670 FDNKGEAIMAQRAYANPDQTISPATPFDMGNGFVNATAALD 710
>sp|Q9FI12|SBT23_ARATH Subtilisin-like protease SBT2.3 OS=Arabidopsis
thaliana OX=3702 GN=SBT2.3 PE=2 SV=1
Length=840
Score = 71.4 bits (173), Expect = 2e-11, Method: Composition-based stats.
Identities = 45/247 (18%), Positives = 73/247 (30%), Gaps = 76/247 (31%)
Query 135 KAAWAQG----YTGHGIVVSILDDGIEKNHPDLAGNYDPGASFD---------------- 174
+ AW + G G+++ +D GI+ NHP N D S+
Sbjct 158 QGAWVKEGGFEIAGEGVIIGFIDTGIDPNHPSFNDN-DSKRSYPIPKHFSGVCEVTPDFP 216
Query 175 -----------------------VNDQDPDPQPRYTQMNDNRHGTRCAGEVAA------- 204
N + P + + HGT A A
Sbjct 217 SGSCNKKLIGARHFAQSAVTRGIFNSSEDYASPF----DGDGHGTHTASVAAGNHGVPVI 272
Query 205 VANNGVC-GVGVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASWGP--- 256
V+N+ G+A A I + L G D V A + + I S S P
Sbjct 273 VSNHNFGYASGIAPRAFISVYKALYKSFGGFAADVVAAIDQAA-QDGVDILSLSITPNRK 331
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
T P +A + + G V A+GN G + S + +
Sbjct 332 PPGVATFFNPIDMALLSAVKA--------GIFVVQAAGNTGPA----PKTMSSFSPWIFT 379
Query 317 ISSATQF 323
+ +++
Sbjct 380 VGASSHD 386
Score = 51.0 bits (120), Expect = 4e-05, Method: Composition-based stats.
Identities = 22/104 (21%), Positives = 39/104 (38%), Gaps = 14/104 (13%)
Query 344 GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKP 403
G + +T+ + +GTS +AP AG+ AL ++ T + + T+
Sbjct 595 GAWSSASTDSTEFEGEKFAMMSGTSMAAPHVAGVAALIKQSYPQFTPSTISSALSTTAL- 653
Query 404 AHLNANDWATNGVGRKVSH-----------SYGYGLLDAGAMVA 436
LN N + R S+ G G ++A A +
Sbjct 654 --LNDNKGSPIMAQRTYSNPDQSLYTATPSDMGSGFVNATAALD 695
>sp|Q9SZY2|SBT37_ARATH Subtilisin-like protease SBT3.7 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.7 PE=3 SV=2
Length=777
Score = 71.4 bits (173), Expect = 2e-11, Method: Composition-based stats.
Identities = 58/356 (16%), Positives = 104/356 (29%), Gaps = 80/356 (22%)
Query 66 HFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLS 125
H + G + + + ++ P+V + + P + W
Sbjct 74 HSFRHGFSGFAAKLTESQAKKIADLPEVVHVIPDRFYK------------PATTRTWDYL 121
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDP----------GASFDV 175
G++ N K Q G +++ I+D G+ N + D
Sbjct 122 GLSP--TNPKNLLNQTNMGEQMIIGIIDSGVWPESEVFNDNEIGPVPSHWKGGCESGEDF 179
Query 176 ND------------------------QDPDPQPRYTQMNDNRHGTRCAGEVAA---VANN 208
N + + N HGT A +A V N
Sbjct 180 NSSHCNKKLIGAKYFINAFLATHESFNSSESLDFISPRGYNGHGTHVA-TIAGGSYVPNT 238
Query 209 GVCGV------GVAYNARIGGVRM---LDGEV-----TDAVEARSLGLNPNHIHIYSASW 254
G+ G A ARI + LD ++ D ++A ++ + + + S S
Sbjct 239 SYKGLAGGTVRGGAPRARIAVYKTCWYLDLDIAACSSADILKAMDEAIH-DGVDVLSLSL 297
Query 255 GPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYT 314
G E D +A AF + G V A+GN G + + +
Sbjct 298 GFEPLYPETDVRDGIATGAFHAVL------KGITVVCAAGNAGPAAQTVGN----TAPWI 347
Query 315 LSISSAT---QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGT 367
L++++ T F Y+ +V + ES +GT
Sbjct 348 LTVAATTLDRSFVTPMTLGNNKVILGQAIYTGTEVGFTSLVYPENPGNSNESFSGT 403
Score = 48.7 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 17/73 (23%), Positives = 31/73 (42%), Gaps = 2/73 (3%)
Query 364 HTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH- 422
+GTS + P +GI+AL + + + ++ +V T+ G RK +
Sbjct 551 LSGTSMATPTISGIVALLKALHPDWSPAAIRSAIVTTAWRTDPFGEQIFAEGSPRKPADP 610
Query 423 -SYGYGLLDAGAM 434
YG GL++
Sbjct 611 FDYGGGLVNPEKA 623
>sp|O53945|MYCP5_MYCTU Mycosin-5 OS=Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv) OX=83332 GN=mycP5 PE=1 SV=1
Length=585
Score = 69.5 bits (168), Expect = 7e-11, Method: Composition-based stats.
Identities = 55/309 (18%), Positives = 94/309 (30%), Gaps = 74/309 (24%)
Query 214 GVAYNARIGGVRM------LDGEVTDAVE-------------ARSLGLNPN-HIHIYSAS 253
G+A I +R L T + AR++ N + + S
Sbjct 271 GIAPGVEIISIRQSSQAFGLKDPYTGDEDPQTAQKIDNVETMARAIVHAANMGASVINIS 330
Query 254 WGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGG-------------REH 300
D + + + A V ++ V A+G+G +
Sbjct 331 -----DVMCMSARNVIDQRALGAAVHYAAVDKDAVIVAAAGDGSKKDCKQNPIFDPLQPD 385
Query 301 DSCNCDGYTNSI-------YTLSISSATQFGNV--------PWYSEACSSTLATTYSSGN 345
D + T + Y L++ + G PW S + T S
Sbjct 386 DPRAWNAVTTVVTPSWFHDYVLTVGAVDANGQPLSKMSIAGPWVSISAPGTDVVGLS--P 443
Query 346 QNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAH 405
+++ I D GTS SA + +G+ AL L+ + + ++ T++P
Sbjct 444 RDDGLINAIDGPDNSLLVPAGTSFSAAIVSGVAALVRAKFPELSAYQIINRLIHTARP-- 501
Query 406 LNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNW---TTVAPQRKCIIDILTEPKDIG 462
R V + GYG++D A W A K + L P+
Sbjct 502 ----------PARGVDNQVGYGVVDP----VAALTWDVPKGPAEPPKQLSAPLVVPQPPA 547
Query 463 KRLEVRKTV 471
R V V
Sbjct 548 PRDMVPIWV 556
Score = 58.7 bits (140), Expect = 1e-07, Method: Composition-based stats.
Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 10/78 (13%)
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND 191
LN+ AW G G G+ V+++D G+ HP L PG + + D +
Sbjct 89 LNLNEAWQFG-RGDGVKVAVIDTGV-TPHPRL-PRLIPGGDYVMAGGDGL-------SDC 138
Query 192 NRHGTRCAGEVAAVANNG 209
+ HGT A +AAV NG
Sbjct 139 DAHGTLVASMIAAVPANG 156
>sp|A0A0M3R8G2|SBT_PETHY Subtilisin-like protease OS=Petunia hybrida
OX=4102 GN=SBT PE=2 SV=1
Length=734
Score = 68.3 bits (165), Expect = 2e-10, Method: Composition-based stats.
Identities = 55/350 (16%), Positives = 95/350 (27%), Gaps = 65/350 (19%)
Query 10 VVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGDYYHFWH 69
+ + L+ + T+ V + A +A YY+ +
Sbjct 5 CIFSIAFLLSFHLTTAQRSTGLQTYIVHV--DKPDAQVLANSAD-------LESYYNSFL 55
Query 70 RGVTKRSLSPHRPRHS---------RLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
S P R HS +V+ +E++ K + P
Sbjct 56 PATVSGSEVPSRIIHSYHHVATGFAAKLSGEEVKEMEKKAGFVSAKLEKVLTLHTTHTPN 115
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDL------AGNYDPGASFD 174
L W + G G+++ +LD GI HP + +
Sbjct 116 FLGLYQNMGF-------WQESNYGKGVIIGLLDTGITPGHPSFSDVNMPSPPAKWKGKCE 168
Query 175 VNDQ-----------DPDPQPRYTQMNDNRHGTRCAGEVAA--------VANNGVCGVGV 215
+ ++ HGT A A N VG+
Sbjct 169 FTGNATCNKKIIGARNFISGSGVPPTDEEGHGTHTASTAAGNFVNDANVFGNANGTAVGM 228
Query 216 AYNARIGGVRML--DGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEA 273
A A I ++ DG + A + + + S S G D D A A A
Sbjct 229 APLAHIAMYKVCSEDGCSDADILAALDAAIDDGVDVLSLSLGGYSDPFYYDNIAIGAFAA 288
Query 274 FFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQF 323
G ++GN G N + + L++ ++T
Sbjct 289 IR---------KGIFVSASAGNDGP----LNSTLSNEAPWILTVGASTHD 325
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 11/50 (22%), Positives = 25/50 (50%), Gaps = 0/50 (0%)
Query 360 CTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAN 409
+GTS S P +GI+AL A+ + + ++ ++ ++ ++L
Sbjct 516 TFNIISGTSMSCPHLSGIVALLKSAHPDWSPAAIKSAIMTSADQSNLEGQ 565
>sp|Q9ZUF6|SBT18_ARATH Subtilisin-like protease SBT1.8 OS=Arabidopsis
thaliana OX=3702 GN=SBT1.8 PE=1 SV=1
Length=754
Score = 67.5 bits (163), Expect = 3e-10, Method: Composition-based stats.
Identities = 47/302 (16%), Positives = 97/302 (32%), Gaps = 73/302 (24%)
Query 115 DPKFPQQWYLSGVTQ-RDLNVK-AAWAQGYTGHGIVVSILDDGI--------EKNHPDLA 164
DP + + + + LN + G + +G+++ +LD G+ + + P++
Sbjct 96 DPLY--TLHTTRTPEFLGLNSEFGVHDLGSSSNGVIIGVLDTGVWPESRSFDDTDMPEIP 153
Query 165 GNYDP----GASFD-------------------------VNDQDPDPQPRYTQMNDNRHG 195
+ G+ FD + + PR + + HG
Sbjct 154 SKWKGECESGSDFDSKLCNKKLIGARSFSKGFQMASGGGFSSKRESVSPR----DVDGHG 209
Query 196 TRCAGEVA--AVANNGVCGV------GVAYNARIGGVRM---LDGEVTDAVEARSLGLNP 244
T + A AV N G G+A AR+ ++ +D + A +
Sbjct 210 THTSTTAAGSAVRNASFLGYAAGTARGMATRARVATYKVCWSTGCFGSDILAAMDRAI-L 268
Query 245 NHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCN 304
+ + + S S G G A + G G ++GN G S
Sbjct 269 DGVDVLSLSLG--------GGSAPYYRDTIAIGAFSAMER-GVFVSCSAGNSGPTRASVA 319
Query 305 CDGYTNSIYTLSISSATQFGNVPWYSEACSS---TLATTYSSGNQNEKQIVTTDLRQKCT 361
+ + +++ + T + P ++ + T + YS K + + +
Sbjct 320 N----VAPWVMTVGAGTLDRDFPAFANLGNGKRLTGVSLYSGVGMGTKPLELVYNKGNSS 375
Query 362 ES 363
S
Sbjct 376 SS 377
Score = 44.4 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 19/92 (21%), Positives = 36/92 (39%), Gaps = 7/92 (8%)
Query 350 QIVTTDLRQKCTES----HTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAH 405
I T L + + +GTS S P +G+ L A+ + ++ ++ T+
Sbjct 514 AIGPTGLDKDSRRTQFNIMSGTSMSCPHISGLAGLLKAAHPEWSPSAIKSALMTTA-YVL 572
Query 406 LNANDWATNGVGRKVSHSY--GYGLLDAGAMV 435
N N + +S+ Y G G +D +
Sbjct 573 DNTNAPLHDAADNSLSNPYAHGSGHVDPQKAL 604
>sp|Q86XX4|FRAS1_HUMAN Extracellular matrix organizing protein
FRAS1 OS=Homo sapiens OX=9606 GN=FRAS1 PE=1 SV=2
Length=4008
Score = 67.9 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 25/100 (25%), Positives = 35/100 (35%), Gaps = 18/100 (18%)
Query 584 SSGCKTLT-SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCA 642
C + SS C+ C E LH C+ CP G+ C
Sbjct 562 DQSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADATG---------------RCK 606
Query 643 PCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
CH SCA+C GP + C +C +L + C +
Sbjct 607 VCHNSCASCSGPTPSHCTACSPPKALR--QGHCLPRCGEG 644
Score = 65.2 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 24/92 (26%), Positives = 31/92 (34%), Gaps = 18/92 (20%)
Query 592 SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATC 651
S C C L C+ CP G+ Q C CH +C C
Sbjct 725 SPHNCTDCGPSHVLLDGQCLSQCPDGYFHQE----------------GSCTECHPTCRQC 768
Query 652 QGPALTDCLSCPSHASLDPVEQTCSRQSQSSR 683
GP +DC+SC H SL C + +
Sbjct 769 HGPLESDCISCYPHISL--TNGNCRTSCREEQ 798
Score = 54.8 bits (130), Expect = 3e-06, Method: Composition-based stats.
Identities = 24/109 (22%), Positives = 37/109 (34%), Gaps = 18/109 (17%)
Query 576 EGLPVPPESSGCKTLTSSQACVVCEEGFSLH--QKSCVQHCPPGFAPQVLDTHYSTENDV 633
+ P ++ C + S +C C + + + + C P +
Sbjct 902 DNHVCQPCNTHCGSCDSQASCTSCRDPNKVLLFGECQYESCAPQYYLDFST--------- 952
Query 634 ETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
+ C C SC+ C GP TDCL C L + C Q SS
Sbjct 953 -----NTCKECDWSCSACSGPLKTDCLQCMDGYVL--QDGACVEQCLSS 994
Score = 51.7 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 24/85 (28%), Positives = 31/85 (36%), Gaps = 18/85 (21%)
Query 596 CVVCEEGFSLH-QKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGP 654
C+ C+ L CV CP G+ + C CH+SC TCQG
Sbjct 827 CLRCQNAHYLLLGDHCVPDCPSGYYAE----------------RGACKKCHSSCRTCQGR 870
Query 655 ALTDCLSCPSHASLDPVEQTCSRQS 679
C SC ++ L TCS
Sbjct 871 GPFSCSSCDTNLVLSH-TGTCSTTC 894
Score = 51.4 bits (121), Expect = 4e-05, Method: Composition-based stats.
Identities = 30/118 (25%), Positives = 38/118 (32%), Gaps = 22/118 (19%)
Query 563 LTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQV 622
+ L Y L P+ C T TS C C+ + CV C GF
Sbjct 451 VHSCGLGFYQAGSLCLACQPQ---CSTCTSGLECSSCQPPLLMRHGQCVPTCGDGFYQDR 507
Query 623 LDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASL---DPVEQTCSR 677
CA CH SCA C GP CL+C + E +C +
Sbjct 508 HS----------------CAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGK 549
Score = 48.7 bits (114), Expect = 3e-04, Method: Composition-based stats.
Identities = 26/105 (25%), Positives = 34/105 (32%), Gaps = 20/105 (19%)
Query 579 PVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRA 638
P P +GCK V + C+ C H+ E+
Sbjct 665 PAPSHCTGCKKPE-EGLQVEQLSDVGIPSGECLAQC---------RAHFYLEST------ 708
Query 639 SVCAPCHASCATCQGPALTDCLSC-PSHASLDPVEQTCSRQSQSS 682
+C CH SC C G + +C C PSH LD C Q
Sbjct 709 GICEACHQSCFRCAGKSPHNCTDCGPSHVLLDGQ---CLSQCPDG 750
Score = 47.9 bits (112), Expect = 4e-04, Method: Composition-based stats.
Identities = 20/115 (17%), Positives = 24/115 (21%), Gaps = 18/115 (16%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
S C C C+ F L + CVQ C G+ C
Sbjct 1006 DSYCLQCQGPHECTRCKGPFLLLEAQCVQECGKGYFADHA--------------KHKCTA 1051
Query 644 CHASCATCQGPALTDCLSCPSHASLD--PVEQTCSRQSQSSRESPPQQQPPRLPP 696
C C C C C L C + P
Sbjct 1052 CPQGCLQCSHR--DRCHLCDHGFFLKSGLCVYNCVPGFSVHTSNETCSGKIHTPS 1104
Score = 47.1 bits (110), Expect = 9e-04, Method: Composition-based stats.
Identities = 30/114 (26%), Positives = 42/114 (37%), Gaps = 24/114 (21%)
Query 572 GTAPEGLPVPPESSGCKTLTSSQ--ACVVCEEGFSL-HQKSCVQHCPPGFAPQVLDTHYS 628
G E S C+T +C C+ L H +C C PG HY
Sbjct 849 GYYAERGACKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPG--------HYL 900
Query 629 TENDVETIRASVCAPCHASCATCQGPALTDCLSC--PSHASL--DPVEQTCSRQ 678
+N VC PC+ C +C A C SC P+ L + ++C+ Q
Sbjct 901 DDNH-------VCQPCNTHCGSCDSQA--SCTSCRDPNKVLLFGECQYESCAPQ 945
Score = 46.0 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 21/99 (21%), Positives = 29/99 (29%), Gaps = 19/99 (19%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
+GC T + L C C GF R C+
Sbjct 517 CAGCWGPTEKHCLACRDPLHVLRDGGCESSCGKGFYN----------------RQGTCSA 560
Query 644 CHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C SC +C GP+ CL+C L + C +
Sbjct 561 CDQSCDSC-GPSSPRCLTCTEKTVLH--DGKCMSECPGG 596
Score = 42.1 bits (97), Expect = 0.026, Method: Composition-based stats.
Identities = 24/121 (20%), Positives = 41/121 (34%), Gaps = 29/121 (24%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQA---------CVVCEEGFSLHQKSCVQHCPPGFAPQ 621
Y + + ++ CK S + C+ C +G+ L +CV+ C F
Sbjct 939 YESCAPQYYLDFSTNTCKECDWSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFYQD 998
Query 622 VLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
+ +C C + C CQGP +C C L +E C ++
Sbjct 999 ----------------SGLCKNCDSYCLQCQGPH--ECTRCKGPFLL--LEAQCVQECGK 1038
Query 682 S 682
Sbjct 1039 G 1039
Score = 40.2 bits (92), Expect = 0.11, Method: Composition-based stats.
Identities = 22/102 (22%), Positives = 30/102 (29%), Gaps = 23/102 (23%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQ-KSCVQHCPPGFAPQVLDTHYSTENDVETIRASV 640
P+ C S C +C++ L Q CV C GF S+
Sbjct 423 PDCLTCS--QSPDHCDLCQDPTKLLQNGWCVHSCGLGFY----------------QAGSL 464
Query 641 CAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C C C+TC +C SC + C
Sbjct 465 CLACQPQCSTCTSGL--ECSSCQPPLLMR--HGQCVPTCGDG 502
>sp|Q6EZC2|SUBA_ECOLX Subtilase cytotoxin subunit A OS=Escherichia
coli OX=562 GN=subA PE=1 SV=1
Length=347
Score = 66.0 bits (159), Expect = 4e-10, Method: Composition-based stats.
Identities = 48/263 (18%), Positives = 89/263 (34%), Gaps = 48/263 (18%)
Query 171 ASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGE 230
A F QD P P HGT A +A+ GV +A I R++
Sbjct 67 AKFSFT-QDGSPFPVKKSEALYIHGTAMASLIAS----RYGIYGVYPHALISSRRVIPDG 121
Query 231 VTD----AVEAR--SLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGG 284
V D A+E+ ++ L P I + S G + L+ GR
Sbjct 122 VQDSWIRAIESIMSNVFLAPGEEKIINISGGQKGVASASVWTELLSR--------MGRNN 173
Query 285 LGSIFVWASGNGGRE------HDSCNCDGY--TNSIY-----TLSISSATQFGNVPWYSE 331
+ V A GN G + Y +S+ + +++ Q Y +
Sbjct 174 -DRLIVAAVGNDGADIRKLSAQQRIWPAAYHPVSSVNKKQDPVIRVAALAQ------YRK 226
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKC---------TESHTGTSASAPLAAGIIALTL 382
+ L +G++ V + T + +GTS + + +G++A
Sbjct 227 GETPVLHGGGITGSRFGNNWVDIAAPGQNITFLRPDAKTGTGSGTSEATAIVSGVLAAMT 286
Query 383 EANKNLTWRDMQHLVVQTSKPAH 405
N T +++ +++++
Sbjct 287 SCNPRATATELKRTLLESADKYP 309
>sp|O82777|SBT3_SOLLC Subtilisin-like protease SBT3 OS=Solanum
lycopersicum OX=4081 GN=sbt3 PE=1 SV=1
Length=761
Score = 65.6 bits (158), Expect = 1e-09, Method: Composition-based stats.
Identities = 60/321 (19%), Positives = 101/321 (31%), Gaps = 83/321 (26%)
Query 60 IFGDYYHFWHRGVT---KRSLSPHRPRH-----------------SRLQREPQVQWLEQQ 99
+F D++H WH K S+ R S + + ++ L++
Sbjct 39 VFTDHHH-WHSSTIDSIKASVPSSVDRFHSAPKLVYSYDNVLHGFSAVLSKDELAALKKL 97
Query 100 VAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGI--- 156
+D EP L+ + W G ++V++LD GI
Sbjct 98 PGFISAYKDRTVEPHTTHTSDFLKLNPSSG-------LWPASGLGQDVIVAVLDSGIWPE 150
Query 157 -----EKNHPDLAGNYDP------------------GASFDVND----QDPDPQ-PRYTQ 188
+ P++ + GA++ N DP +
Sbjct 151 SASFQDDGMPEIPKRWKGICKPGTQFNASMCNRKLIGANY-FNKGILANDPTVNITMNSA 209
Query 189 MNDNRHGTRCAGEVAAVANNGVCGV--------GVAYNARIGGVR--MLDGEVTDAVEAR 238
+ + HGT CA A GV GVA AR+ + +G T + A
Sbjct 210 RDTDGHGTHCASITAGNFAKGVSHFGYAPGTARGVAPRARLAVYKFSFNEGTFTSDLIAA 269
Query 239 SLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGR 298
+ + + S S+G L E+A S G G + ++GN G
Sbjct 270 MDQAVADGVDMISISYGYR--------FIPLYEDAISIA-SFGAMMKGVLVSASAGNRGP 320
Query 299 EHDSCNCDGYTNSIYTLSISS 319
S N S + L ++S
Sbjct 321 GIGSLNN----GSPWILCVAS 337
Score = 36.3 bits (82), Expect = 1.5, Method: Composition-based stats.
Identities = 25/153 (16%), Positives = 48/153 (31%), Gaps = 2/153 (1%)
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWR 391
A + Y N I T L +GTS +AP AAGI A+ A+ +
Sbjct 503 APGVLILAAYPP-NVFATSIGTNILLSTDYILESGTSMAAPHAAGIAAMLKAAHPEWSPS 561
Query 392 DMQHLVVQTSKPAHLNANDWATNGVGRKVSH-SYGYGLLDAGAMVALAQNWTTVAPQRKC 450
++ ++ T+ P + + + G G +D + +
Sbjct 562 AIRSAMMTTADPLDNTRKPIKDSDNNKAATPLDMGAGHVDPNRALDPGLVYDATPQDYVN 621
Query 451 IIDILTEPKDIGKRLEVRKTVTACLGEPNHITR 483
++ L ++ K + C +
Sbjct 622 LLCSLNFTEEQFKTIARSSASHNCSNPSADLNY 654
>sp|O49607|SBT16_ARATH Subtilisin-like protease SBT1.6 OS=Arabidopsis
thaliana OX=3702 GN=SBT1.6 PE=2 SV=1
Length=764
Score = 65.6 bits (158), Expect = 1e-09, Method: Composition-based stats.
Identities = 60/352 (17%), Positives = 105/352 (30%), Gaps = 98/352 (28%)
Query 44 VANSVARKHGFLNLG----QIFGDYYHFWHRGVTKRSLSPHRPRHSR------------- 86
A+ A+ F G IF +YH++ + S H
Sbjct 20 AASQAAKTFIFRIDGGSMPSIFPTHYHWYSTEFAEESRIVHVYHTVFHGFSAVVTPDEAD 79
Query 87 -LQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGH 145
L+ P V + + +R+++ + Q N K W++ G
Sbjct 80 NLRNHPAVLAVFED-----RRRELHTTRSPQFLGLQ-----------NQKGLWSESDYGS 123
Query 146 GIVVSILDDGI---EKNHPDLA---------------GNYDP--------GASF------ 173
+++ + D GI ++ DL + P GA F
Sbjct 124 DVIIGVFDTGIWPERRSFSDLNLGPIPKRWRGVCESGARFSPRNCNRKIIGARFFAKGQQ 183
Query 174 -DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA--------VANNGVCGVGVAYNARIGGV 224
V + + + HGT + A GVA ARI
Sbjct 184 AAVIGGINKTVEFLSPRDADGHGTHTSSTAAGRHAFKASMSGYASGVAKGVAPKARIAAY 243
Query 225 RM-------LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRG 277
++ LD ++ A +A + + + S S G D + + G
Sbjct 244 KVCWKDSGCLDSDILAAFDAAV----RDGVDVISISIGGGD-----GITSPYYLDPIAIG 294
Query 278 VSQGRGGLGSIFVWASGNGGREHDSCNCDGYTN-SIYTLSISSATQFGNVPW 328
S G G ++GN G S TN + + ++ ++T N P
Sbjct 295 -SYGAASKGIFVSSSAGNEGPNGMS-----VTNLAPWVTTVGASTIDRNFPA 340
Score = 60.6 bits (145), Expect = 5e-08, Method: Composition-based stats.
Identities = 33/191 (17%), Positives = 60/191 (31%), Gaps = 26/191 (14%)
Query 352 VTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDW 411
+ +D R+ +GTS + P +G AL A+ + + ++ ++ T+ +
Sbjct 522 LPSDPRKTEFNILSGTSMACPHVSGAAALLKSAHPDWSPAVIRSAMMTTTNLVDNSNRSL 581
Query 412 ATNGVGRKVSH-SYGYGLLDAGAMVALAQNWTTVAPQRK---CIIDILTEPKDIGKRLEV 467
G+ + YG G L+ G + + C I + + R V
Sbjct 582 IDESTGKSATPYDYGSGHLNLGRAMNPGLVYDITNDDYITFLCSIGYGPKTIQVITRTPV 641
Query 468 RKTVTACLGEPNHITRLEHAQARLTLSYNRRGDL------------------AIHLVSPM 509
R T P ++ NRRG + + SP
Sbjct 642 RCPTTR-KPSPGNLNY---PSITAVFPTNRRGLVSKTVIRTATNVGQAEAVYRARIESPR 697
Query 510 GTRSTLLAARP 520
G T+ R
Sbjct 698 GVTVTVKPPRL 708
>sp|Q9FHA4|SBT19_ARATH Subtilisin-like protease SBT1.9 OS=Arabidopsis
thaliana OX=3702 GN=SBT1.9 PE=2 SV=1
Length=736
Score = 65.2 bits (157), Expect = 2e-09, Method: Composition-based stats.
Identities = 55/314 (18%), Positives = 93/314 (30%), Gaps = 66/314 (21%)
Query 138 WAQGYTGHGIVVSILDDGIEKNHPDLAGNY------DPGASFDVND-------------- 177
W G GIV+ I+D GI + P + + + N
Sbjct 118 WPVSNYGAGIVIGIIDTGIWPDSPSFHDDGVGSVPSKWKGACEFNSSSLCNKKLIGAKVF 177
Query 178 ------QDPDPQPR-----YTQMNDNRHGTRCAGEVAA--VANNGV------CGVGVAYN 218
+PD + + + HGT A A V N G+A +
Sbjct 178 NKGLFANNPDLRETKIGQYSSPYDTIGHGTHVAAIAAGNHVKNASYFSYAQGTASGIAPH 237
Query 219 ARIGGVRML---DGEVTDAVEARSLGLNPNHIHIYSASWG-PEDDGKTVDGPARLAEEAF 274
A + + +D + A + + +H+ S S G +D DG E
Sbjct 238 AHLAIYKAAWEEGIYSSDVIAAIDQAI-RDGVHVISLSLGLSFEDDDDNDGFG--LENDP 294
Query 275 FRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISS---------ATQFGN 325
S G V + GN G + + +++ + FGN
Sbjct 295 IAVASFAAIQKGVFVVTSGGNDGP----YYWSLINGAPWIMTVGAGTIGRQFQGTLTFGN 350
Query 326 VPWYS-------EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGII 378
+S E S TY E + + + + G+ + G
Sbjct 351 RVSFSFPSLFPGEFPSVQFPVTYIESGSVENKTLANRIVVCNENINIGSKLHQIRSTGAA 410
Query 379 ALTLEANKNLTWRD 392
A+ L +K L +D
Sbjct 411 AVVLITDKLLEEQD 424
Score = 47.5 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 17/57 (30%), Positives = 29/57 (51%), Gaps = 4/57 (7%)
Query 364 HTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTS----KPAHLNANDWATNGV 416
TGTS +AP AG+ AL + + N + ++ ++ T+ P + A +TN V
Sbjct 525 LTGTSMAAPHVAGVAALIKQVHPNWSPSAIKSAIMTTALTLDNPLAVGAGHVSTNKV 581
>sp|Q8SS86|SPL2_ENCCU Putative subtilisin-like proteinase 2 OS=Encephalitozoon
cuniculi (strain GB-M1) OX=284813 GN=SPL2 PE=2
SV=1
Length=535
Score = 63.7 bits (153), Expect = 4e-09, Method: Composition-based stats.
Identities = 56/284 (20%), Positives = 91/284 (32%), Gaps = 58/284 (20%)
Query 115 DPKFPQQW-----YLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDP 169
+ F W + V + L + +TG G+ + +LD I
Sbjct 215 NNYFYDNWIFRVLQIKRVMTKFLGSYEYY---HTGKGVNIFLLDTAI------------- 258
Query 170 GASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDG 229
+ D N HG A + N G A ++R+ + ++D
Sbjct 259 ------SSMDGACNLSGRLEACNAHGNVMAELLVGKTN------GFAKDSRLSVLDVVDC 306
Query 230 EVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIF 289
+ A+ GL S GP V GP A G++
Sbjct 307 DGKVALSEMIHGLEG-----LRESGGPSILVFGVSGPYS----ASLNSAVDRISSRGTVV 357
Query 290 VWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEK 349
V +GN SCN +S +++ S + + +S ++ G
Sbjct 358 VSPAGNS--HDQSCNYSP-GSSKSVINVGSVDKHAGISRFSNHG--DCIRMFAPGE---- 408
Query 350 QIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDM 393
D+ Q S TGTS SA + A IAL LE + + +
Sbjct 409 -----DVLQDS--SLTGTSLSAAIVASSIALFLETSPRAAFPQI 445
>sp|F4HYR6|SBT24_ARATH Subtilisin-like protease SBT2.4 OS=Arabidopsis
thaliana OX=3702 GN=SBT2.4 PE=1 SV=1
Length=832
Score = 63.3 bits (152), Expect = 7e-09, Method: Composition-based stats.
Identities = 68/366 (19%), Positives = 108/366 (30%), Gaps = 72/366 (20%)
Query 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
+ Y F H + ++ + +L + V+ +E+ K P + PQ
Sbjct 95 YTKLYSFKHV-INAIAVRTTASQAKKLGKTKGVKAVEEDKG---VKLMTTYTPDFLELPQ 150
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHP-----DLAGNYDPGASFDV 175
Q + + D G IV+ +D GI HP DL Y S
Sbjct 151 QVWQKISNEGDRRA---------GEDIVIGFVDTGINPTHPSFAALDLTNPYSSNLSRLH 201
Query 176 NDQDPDPQPRYTQMNDNR--------------------------------HGTRCAGEVA 203
D + P + + N HG+ A A
Sbjct 202 FSGDCEIGPFFPPGSCNGKIISARFFSAGARASGALNSSLDILSPFDASGHGSHVASIAA 261
Query 204 AVANNGVCG--------VGVAYNARIGGVRMLD---GEVTDAVEARSLGLNPNHIHIYSA 252
A V G+A +RI + + G + D + A + + + + +
Sbjct 262 GNAGVPVIVDGFFYGRASGMAPRSRIAVYKAIYPSIGTLVDVIAAIDQAI-MDGVDVLTL 320
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
S GP++ VD P L F + R G V A GN G S S
Sbjct 321 SVGPDE--PPVDKPTVLGI--FDLAMLLAR-KAGVFVVQAVGNNGPSPSSVLSY----SP 371
Query 313 YTLSISS-ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASA 371
+ + +++ T T+ SG +V L T S
Sbjct 372 WVVGVAAGNTDRSYPAPLILDGGQTVQGVGLSGPTLGAPLVQHRLVLAKDAVRTNGSVLQ 431
Query 372 PLAAGI 377
PL I
Sbjct 432 PLTRDI 437
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 26/154 (17%), Positives = 48/154 (31%), Gaps = 8/154 (5%)
Query 344 GNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKP 403
G + L + +GTS + P AGI AL + N + T + + T+
Sbjct 594 GAWSLPSAFDPILTGRSFAILSGTSMATPHIAGIGALIKQLNPSWTPAMIASAISTTANE 653
Query 404 AHLNAN----DWATNGVGRKVSH-SYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEP 458
N ++ +H +G G ++ + + + I L
Sbjct 654 YDSNGEIISAEYYELSRLFPSNHFDHGAGHVNPARALD---PGLVLPAGFEDYISFLCSL 710
Query 459 KDIGKRLEVRKTVTACLGEPNHITRLEHAQARLT 492
+I T C +H L H ++
Sbjct 711 PNISPATIRDATGVLCTTTLSHPANLNHPSVTIS 744
>sp|Q8I430|SUB3_PLAF7 Subtilisin-like protease 3 OS=Plasmodium
falciparum (isolate 3D7) OX=36329 GN=SUB3 PE=1 SV=1
Length=769
Score = 61.8 bits (148), Expect = 2e-08, Method: Composition-based stats.
Identities = 41/223 (18%), Positives = 81/223 (36%), Gaps = 14/223 (6%)
Query 187 TQMNDNRHGTRCAGEVAA-VANNGVCGVGVAYNARIGGVRMLD----GEVTDAVEARSLG 241
T + + HGT AG +A G++ A++ + L+ G ++D +E +
Sbjct 516 TSNDGHGHGTFIAGIIAGNSPKGKKGIKGISKKAKLIICKALNNNNAGYISDILECFNFC 575
Query 242 LNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFV-WASGNGGREH 300
I +AS+ ++ + ++ +S + A
Sbjct 576 AKK-KARIINASFASTTHYPSLFQALKELQDKDILVISSSGNCSSNSKCKQAFQECNLNI 634
Query 301 DSCNCDGYT---NSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLR 357
Y+ N+I ++S GN+ ++C + Y I++T
Sbjct 635 QKLYPAAYSADLNNIISVSNIIQQSNGNIVLSPDSC---YSPNYVHLAAPGGNIIST-FP 690
Query 358 QKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQT 400
+GTS SA + G+ +L L N NLT + + L ++
Sbjct 691 NNKYAISSGTSFSASVITGLASLVLSINSNLTSQQVIELFKKS 733
Score = 37.5 bits (85), Expect = 0.61, Method: Composition-based stats.
Identities = 11/27 (41%), Positives = 16/27 (59%), Gaps = 0/27 (0%)
Query 147 IVVSILDDGIEKNHPDLAGNYDPGASF 173
+ V I+D GI++NH DL N +F
Sbjct 366 VNVCIIDTGIDENHIDLKDNIIEKKTF 392
>sp|P81715|LIE1_STREX Leupeptin-inactivating enzyme 1 OS=Streptomyces
exfoliatus OX=1905 GN=lieA PE=1 SV=2
Length=438
Score = 61.0 bits (146), Expect = 2e-08, Method: Composition-based stats.
Identities = 29/141 (21%), Positives = 53/141 (38%), Gaps = 12/141 (9%)
Query 431 AGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQAR 490
A A+ L Q + P + TV+ G T+
Sbjct 309 AYAIWTLGAGTPVPPGQSFENTADVNVPDSPAAAVSSPITVSGVTGNAPATTK-----VD 363
Query 491 LTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDW-AFMTTHSWDEDPSGEWVL 549
+ + + RGDL + LV+P GT L H+ S ++ T ++ E +G W L
Sbjct 364 VNIVHTYRGDLVVDLVAPDGTVYNL-----HNRSGGSADNLVQTYTVNASSEVANGVWNL 418
Query 550 EIENTSEANNYGTLTKFTLVL 570
+++T+ A + G + + +
Sbjct 419 RVKDTA-AQDVGYINSWKITF 438
>sp|A9QY40|SBT1_LOTJA Subtilisin-like protease 1 OS=Lotus japonicus
OX=34305 GN=SBTM1 PE=2 SV=1
Length=750
Score = 61.4 bits (147), Expect = 2e-08, Method: Composition-based stats.
Identities = 35/213 (16%), Positives = 61/213 (29%), Gaps = 34/213 (16%)
Query 135 KAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDP-------------GASFDVN----- 176
+ W G G+++ ++D GI H P G S N
Sbjct 132 QGLWNDSNLGKGVIIGVIDTGIYPFHLSFNDEGMPPPPAKWKGHCEFTGGSVCNNKLIGA 191
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAA-------VANNGVCG-VGVAYNARIGGVRMLD 228
+ D HGT A E A V N G+A +A + ++
Sbjct 192 RNLVKSAIQEPPYEDFFHGTHTAAEAAGRFVEGASVFGNARGTAAGMAPDAHLAIYKVCS 251
Query 229 GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
+V D ++ + I G E+ G G
Sbjct 252 SKVKDECPESAILAA---MDIAIEDGVDVLSLSLGLGSLPFFEDPIAIGAFAATQ-KGIF 307
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
++ N G + S + + L++ ++T
Sbjct 308 VSCSAANSGPHYSS----LSNEAPWILTVGAST 336
Score = 50.2 bits (118), Expect = 7e-05, Method: Composition-based stats.
Identities = 26/117 (22%), Positives = 45/117 (38%), Gaps = 15/117 (13%)
Query 307 GYTNSIYTLSISSATQF----GNVPWYSEACSSTLATTYSSGNQNEKQI----------- 351
Y NS YT + + Q ++ A SS + S G I
Sbjct 459 AYINSTYTPTATVLFQGTIIGDSLAPSVAAFSSRGPSQQSPGILKPDIIGPGVNILAAWA 518
Query 352 VTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA 408
V+ D + + +GTS S P +GI AL A+ + + ++ ++ T+ +L
Sbjct 519 VSVDNKIPAFDIISGTSMSCPHLSGIAALLKSAHPDWSPAAIKSAIMTTANTLNLRG 575
>sp|Q9LVJ1|SBT14_ARATH Subtilisin-like protease SBT1.4 OS=Arabidopsis
thaliana OX=3702 GN=SBT1.4 PE=2 SV=1
Length=777
Score = 61.4 bits (147), Expect = 3e-08, Method: Composition-based stats.
Identities = 55/302 (18%), Positives = 94/302 (31%), Gaps = 75/302 (25%)
Query 66 HFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLS 125
+ + R V S + + L+R P V + A+ P F Q L
Sbjct 71 YSYSRAVHGFSARLSPIQTAALRRHPSVISVIPDQAREIHT---THTPAFLGFSQNSGL- 126
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDP------------GASF 173
W+ G ++V +LD GI HP + + G F
Sbjct 127 ------------WSNSNYGEDVIVGVLDTGIWPEHPSFSDSGLGPIPSTWKGECEIGPDF 174
Query 174 DVND----------------------QDPDPQPRYTQMNDNRHGTRCAGEVAA--VANNG 209
+ + + + + HGT A A VAN
Sbjct 175 PASSCNRKLIGARAFYRGYLTQRNGTKKHAAKESRSPRDTEGHGTHTASTAAGSVVANAS 234
Query 210 VCGV------GVAYNARIGGVRML---DGEVTDAVEARSLGLNPNHIHIYSASWGPEDDG 260
+ G+A ARI ++ +D + A + + +H+ S S G
Sbjct 235 LYQYARGTATGMASKARIAAYKICWTGGCYDSDILAAMDQAVA-DGVHVISLSVGASGSA 293
Query 261 KTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTN-SIYTLSISS 319
+A AF G G + ++GN G N + TN + + L++ +
Sbjct 294 PEY-HTDSIAIGAF------GATRHGIVVSCSAGNSGP-----NPETATNIAPWILTVGA 341
Query 320 AT 321
+T
Sbjct 342 ST 343
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 21/118 (18%), Positives = 42/118 (36%), Gaps = 2/118 (2%)
Query 362 ESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVS 421
+GTS S P +G+ AL +A+ + + ++ +V T+ + G+ +
Sbjct 540 NIISGTSMSCPHVSGLAALLRKAHPDWSPAAIKSALVTTAYDVENSGEPIEDLATGKSSN 599
Query 422 HS-YGYGLLDAGAMVALAQNW-TTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGE 477
+G G +D + + V + + E I L+ AC
Sbjct 600 SFIHGAGHVDPNKALNPGLVYDIEVKEYVAFLCAVGYEFPGILVFLQDPTLYDACETS 657
>sp|Q9ZSB1|SBT3A_ARATH Subtilisin-like protease SBT3.10 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.10 PE=3 SV=2
Length=759
Score = 61.0 bits (146), Expect = 4e-08, Method: Composition-based stats.
Identities = 50/319 (16%), Positives = 91/319 (29%), Gaps = 75/319 (24%)
Query 56 NLGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTD 115
L I Y H + K + S + ++ P+V + T
Sbjct 63 VLDSIVYSYRHGFSGFAAKLTESQAQ----QISELPEVVQVIPNTLYEMTT--------- 109
Query 116 PKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN-YDP----- 169
+ W GV+ N + + G+ ++V ++D G+ Y P
Sbjct 110 ---TRTWDYLGVSPG--NSDSLLQKANMGYNVIVGVIDTGVWPESEMFNDKGYGPIPSRW 164
Query 170 ---------------------GASF--DVND------QDPDPQPRYTQMNDNRHGTRCAG 200
GA + D N+ + + + N HGT A
Sbjct 165 KGGCESGELFNGSIHCNRKLIGAKYFIDANNAQFGVLNKTENPDYLSPRDFNGHGTHVAS 224
Query 201 EVAA--VANNGVCGV------GVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIH 248
+ + N G+ G A I + D ++A ++ + +
Sbjct 225 TIGGSFLPNVSYLGLGRGTARGGAPGVHIAVYKACWVQRGCSGADVLKAMDEAIH-DGVD 283
Query 249 IYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY 308
I S S L F V G V A+ N G +
Sbjct 284 ILSLSLQTSVPLFPETDARELTSVGAFHAV-----AKGIPVVAAASNAGPTAQT----LS 334
Query 309 TNSIYTLSISSATQFGNVP 327
+ + L++++ TQ + P
Sbjct 335 NVAPWVLTVAATTQDRSFP 353
Score = 59.1 bits (141), Expect = 1e-07, Method: Composition-based stats.
Identities = 23/125 (18%), Positives = 48/125 (38%), Gaps = 3/125 (2%)
Query 314 TLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPL 373
++S AT P S + + + G I + +GTS + P+
Sbjct 484 SVSTKVATFSSRGPN-SVSPAILKPDIAAPGVNILAAISPNSINDGGFAMMSGTSMATPV 542
Query 374 AAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH--SYGYGLLDA 431
+G++ L + + + ++ +V T+ + +G RK++ YG GL++
Sbjct 543 VSGVVVLLKSLHPDWSPSAIKSAIVTTAWRTDPSGEPIFADGSSRKLADPFDYGGGLINP 602
Query 432 GAMVA 436
V
Sbjct 603 EKAVK 607
>sp|O05458|MYCP2_MYCTU Mycosin-2 OS=Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv) OX=83332 GN=mycP2 PE=1 SV=1
Length=550
Score = 60.2 bits (144), Expect = 5e-08, Method: Composition-based stats.
Identities = 49/270 (18%), Positives = 76/270 (28%), Gaps = 64/270 (24%)
Query 213 VGVAYNARIGGVRMLD-----------GEVTD--------AVEARSLGLNPN-HIHIYSA 252
VGVA +A I +R G +D AR++ N + +
Sbjct 238 VGVAPHATIISIRQSSRAFEPVNPSSAGPNSDEKVKAGTLDSVARAVVHAANMGAKVINI 297
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNC------- 305
S + A + + ++ V A+GN G N
Sbjct 298 SV-----TACLPAAAPGDQRVLGAALWYAATVKDAVIVAAAGNDGEAGCGNNPMYDPLDP 352
Query 306 -------------DGYTNSIYTLSISSATQFGNV-------PWYSEACSSTLATTYSSGN 345
S Y LS+ + +G PW A T S
Sbjct 353 SDPRDWHQVTVVSSPSWFSDYVLSVGAVDAYGAALDKSMSGPWVGVAAPGTHIMGLSPQG 412
Query 346 QNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAH 405
+ GTS SA +G+ AL LT + + +VQ++
Sbjct 413 GGPVNAYPPSRPGEKNMPFWGTSFSAAYVSGVAALVRAKFPELTAYQVINRIVQSAHNPP 472
Query 406 LNANDWATNGVGRKVSHSYGYGLLDAGAMV 435
V + GYGL+D A +
Sbjct 473 A------------GVDNKLGYGLVDPVAAL 490
Score = 42.9 bits (99), Expect = 0.013, Method: Composition-based stats.
Identities = 20/75 (27%), Positives = 35/75 (47%), Gaps = 12/75 (16%)
Query 132 LNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND 191
+N+ AW Q TG+G+ V+++D G+ N P L PG + + + +
Sbjct 83 VNISKAW-QYSTGNGVPVAVIDTGVSPN-PRLP--VVPGGDYIMGE--------DGLSDC 130
Query 192 NRHGTRCAGEVAAVA 206
+ HGT + +AA
Sbjct 131 DAHGTVVSSIIAAAP 145
>sp|P0DW09|HETQ2_PODAS Subtilisin-like protease het-Q2 OS=Podospora
anserina OX=2587412 GN=het-Q2 PE=1 SV=1
Length=366
Score = 59.4 bits (142), Expect = 6e-08, Method: Composition-based stats.
Identities = 42/264 (16%), Positives = 81/264 (31%), Gaps = 60/264 (23%)
Query 147 IVVSILDDGIEKNHPDLA-------------------------GNYDPGASFDV-----N 176
+ +++LD G + +HPD + F +
Sbjct 29 VRIAVLDTGFDGSHPDFSHPRTAYFTGPFSDLPQPEKDEEPQLTRIKAYHDFCQPSPPGD 88
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRM--------LD 228
Q P PQP ++ ++ HGT AG + + +A A + R+ L
Sbjct 89 RQGPPPQP-HSMVDLAGHGTAIAGLI----------LRLAPRAELVIGRVCHGVDSNELS 137
Query 229 GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
V A +HI + S G L E R +
Sbjct 138 APDPSRVAAAIRWAITQKVHIINLSLGYR--------NQPLKELLPLRAALLEAQRSNIL 189
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNE 348
++ N G + +++ + + + S G+ P S +S + + +N
Sbjct 190 VFASTSNQGSHEPA--AWPASDARFAIGVHSCNDMGSAPSGSSCKASENGYNFMAVGENL 247
Query 349 KQIVTTDLRQKCTESHTGTSASAP 372
+ + E +G+S + P
Sbjct 248 L-VHRLAQKGGGFELVSGSSFATP 270
>sp|Q9ZSB0|SBT39_ARATH Subtilisin-like protease SBT3.9 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.9 PE=3 SV=1
Length=756
Score = 59.8 bits (143), Expect = 9e-08, Method: Composition-based stats.
Identities = 42/256 (16%), Positives = 80/256 (31%), Gaps = 63/256 (25%)
Query 119 PQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG--------NYDPG 170
+ W GV+ N + + G+ ++V ++D G+ + G
Sbjct 110 TRTWDYLGVSPG--NSDSLLQKANMGYNVIVGVIDSGVWPESEMFNDKGFGPIPSRWKGG 167
Query 171 ----------------------------ASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEV 202
A F V ++ +P+ + + HGT A +
Sbjct 168 CESGELFNASIHCNRKLIGAKYFVDGLVAEFGVVNRTQNPE-YLSPRDFAGHGTHVASTI 226
Query 203 AA--VANNGVCGV------GVAYNARIGGVRML-DG--EVTDAVEARSLGLNPNHIHIYS 251
+ N G+ G A I + G D ++A ++ + + I S
Sbjct 227 GGSFLPNVSYVGLGRGTARGGAPGVHIAVYKACWSGYCSGADVLKAMDEAIH-DGVDILS 285
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
S GP + AF G V A+GN G + + +
Sbjct 286 LSLGPSV--PLFPETEHTSVGAFHAVA------KGIPVVIAAGNAGPTAQTISN----VA 333
Query 312 IYTLSISSATQFGNVP 327
+ L++++ TQ + P
Sbjct 334 PWVLTVAATTQDRSFP 349
Score = 56.0 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 21/125 (17%), Positives = 44/125 (35%), Gaps = 2/125 (2%)
Query 314 TLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPL 373
++S AT P N + + +GTS + P+
Sbjct 480 SVSTKVATFSSRGPNSVSPAILKPDIAAPGVNILAAISPNSSINDGGFAMMSGTSMATPV 539
Query 374 AAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH--SYGYGLLDA 431
+G++ L + + + ++ +V T+ + +G RK++ YG GL++
Sbjct 540 VSGVVVLLKSLHPDWSPSAIKSAIVTTAWRTDPSGEPIFADGSSRKLADPFDYGGGLINP 599
Query 432 GAMVA 436
V
Sbjct 600 EKAVK 604
>sp|Q9LZS6|SBT4F_ARATH Subtilisin-like protease SBT4.15 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.15 PE=3 SV=1
Length=766
Score = 59.4 bits (142), Expect = 9e-08, Method: Composition-based stats.
Identities = 44/276 (16%), Positives = 85/276 (31%), Gaps = 67/276 (24%)
Query 82 PRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQG 141
+L RE V + + T+R ++ + W G+ V++ + +
Sbjct 90 HEAEKLSREEGVVSV-----FKNTQRQLHT-------TRSWDFLGL------VESKYKRS 131
Query 142 YT-GHGIVVSILDDGIEKNHPDLAGNYDP------------------------GASFDVN 176
I+V +LD GI+ P GA +
Sbjct 132 VGIESNIIVGVLDTGIDVESPSFNDKGVGPPPAKWKGKCVTGNNFTRCNNKVIGAKYFHI 191
Query 177 DQDPDPQPRYTQMND-NRHGTRCAGEVAAVANNGVCGVGVA--------YNARIGGVRML 227
+ P D + HGT + +A V+ + G+A +ARI ++
Sbjct 192 QSEGLPDGEGDTAADHDGHGTHTSSTIAGVSVSSASLFGIANGTARGGVPSARIAAYKVC 251
Query 228 -DGEVTD-AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGL 285
D TD + A + + I S S G E+ G
Sbjct 252 WDSGCTDMDMLAAFDEAISDGVDIISISIG--------GASLPFFEDPIAIGAFHAM-KR 302
Query 286 GSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
G + ++GN G + + +++++ +
Sbjct 303 GILTTCSAGNNGPGL----FTVSNLAPWVMTVAANS 334
Score = 40.2 bits (92), Expect = 0.076, Method: Composition-based stats.
Identities = 14/73 (19%), Positives = 29/73 (40%), Gaps = 9/73 (12%)
Query 364 HTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHS 423
+GTS + P AA A + + + ++ ++ T+ P + N+ S
Sbjct 539 MSGTSMACPHAAAAAAYVKSFHPDWSPAAIKSALMTTATPMRIKGNEAEL---------S 589
Query 424 YGYGLLDAGAMVA 436
YG G ++ +
Sbjct 590 YGSGQINPRRAIH 602
>sp|A9JQS7|SBTS_LOTJA Subtilisin-like serine-protease S OS=Lotus
japonicus OX=34305 GN=SbtS PE=2 SV=1
Length=759
Score = 59.4 bits (142), Expect = 9e-08, Method: Composition-based stats.
Identities = 34/168 (20%), Positives = 59/168 (35%), Gaps = 30/168 (18%)
Query 177 DQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGV--------AYNARIGGVRML- 227
+ D + + + HGT A +A + V G+ A +AR+ +
Sbjct 198 ENIVDSIFFRSPRDSDGHGTHTASTIAGSIVSNVSLFGMAKGTARGGAPSARLSIYKACW 257
Query 228 -----DGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARL-AEEAFFRGVSQG 281
D +V A++ + + I S S GP D P L E A G
Sbjct 258 FGFCSDADVFAAMDDAI----HDGVDILSLSLGP-------DPPQPLYFENAISVGAFHA 306
Query 282 RGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWY 329
G + ++GN +CN + I+T++ S+ + Y
Sbjct 307 FQ-KGILVSASAGNSVFPRTACNVAPW---IFTVAASTVDREFRSDIY 350
Score = 43.7 bits (101), Expect = 0.008, Method: Composition-based stats.
Identities = 12/77 (16%), Positives = 30/77 (39%), Gaps = 1/77 (1%)
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
+GTS S P + I A+ + + + + ++ ++ + + G +
Sbjct 538 YNIISGTSMSCPHISAISAIIKSHHPSWSPAAIMSAIMTSATVMDNTHSLIGRDPNGTQA 597
Query 421 SH-SYGYGLLDAGAMVA 436
+ YG G ++ A +
Sbjct 598 TPFDYGSGHVNPVASLN 614
>sp|P80561|APX_STRGG Aminopeptidase S OS=Streptomyces griseus
subsp. griseus (strain JCM 4626 / NBRC 13350) OX=455632 GN=SGR_5809
PE=1 SV=2
Length=445
Score = 59.1 bits (141), Expect = 9e-08, Method: Composition-based stats.
Identities = 30/147 (20%), Positives = 54/147 (37%), Gaps = 12/147 (8%)
Query 429 LDAGAMVALAQNWTTVA----PQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRL 484
LD + A WT + P + T I + A G +
Sbjct 306 LDRNSDAAAHAIWTLSSGTGEPPTGEGVFSNTTDVAIPDAGAAVTSSVAVTGRTGNAPA- 364
Query 485 EHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFND-WAFMTTHSWDEDP 543
Q + + + RGDL + L++P GT L + S D ++ A T ++ E
Sbjct 365 -ALQVGVDIKHTYRGDLVVDLLAPDGTAYRL----KNSSSGDSADNVIATYTVNASSEVA 419
Query 544 SGEWVLEIENTSEANNYGTLTKFTLVL 570
+G W L +++ + + G + + L
Sbjct 420 NGSWKLRVQDIARQDT-GYIDSWKLTF 445
>sp|Q9GTN7|TAGA_DICDI Serine protease/ABC transporter B family
protein tagA OS=Dictyostelium discoideum OX=44689 GN=tagA PE=1
SV=2
Length=1752
Score = 59.8 bits (143), Expect = 1e-07, Method: Composition-based stats.
Identities = 54/280 (19%), Positives = 92/280 (33%), Gaps = 42/280 (15%)
Query 74 KRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLN 133
K S ++ V W+E + + + P++ Y
Sbjct 240 KNSKLSLESIIYKISTRSLVYWIEP-----SSSKLIKHTPSNKFAH---YSIQSGSASTT 291
Query 134 VKAAWAQ-GYTGHGIVVSILDDGIEKNHPDLAGNYDPGAS----FDVNDQDPDPQPRYTQ 188
W G G G +V D GI+ NH G++ + + D
Sbjct 292 STPIWDVIGIKGDGEIVGCADTGIDINHCFFYDTNPIGSTHRKIISYSSGNGDQIDEI-- 349
Query 189 MNDNRHGTRCAGEVAAVANNGVCG---VGVAYNARIGGVRMLDGEVTDAVEARSLGLNPN 245
+ HGT G + G A N+++ V + G L + N
Sbjct 350 ---DGHGTHIVGTIIGSTTVDPSVSEFSGGAPNSKVAFVDLQVGSGNG------LSIQSN 400
Query 246 HIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQ-----GRGGLGSIFVWASGNGGREH 300
IY +++ + + K F+ GV++ + V ++GN
Sbjct 401 LTAIYQSTY--DQNAKVHCDAWNSNIGPFYTGVTEMIDRFQWDHPDFLVVRSAGN----- 453
Query 301 DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATT 340
+ N G+ NSIYTLS S ++ V S SST ++
Sbjct 454 -NVNF-GF-NSIYTLSQESTSKNSLVVGSSNQPSSTYLSS 490
>sp|Q9MAP4|SBT32_ARATH Subtilisin-like protease SBT3.2 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.2 PE=2 SV=1
Length=734
Score = 59.1 bits (141), Expect = 1e-07, Method: Composition-based stats.
Identities = 50/291 (17%), Positives = 92/291 (32%), Gaps = 59/291 (20%)
Query 117 KFPQQW-YLSGVTQRDLNVKAAWAQGYTGHGIVVSILDD---------------GIEKNH 160
+ + W YL ++ N+ Q G +++ ++D G NH
Sbjct 88 QTTRTWDYLQHTSKHPKNIL---NQTNMGDQLIIGVVDSVTLNWFGFILLKQEYGQSLNH 144
Query 161 P-----DLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA--VANNGVCGV 213
D N + PR + + HGT A A V + G+
Sbjct 145 SVTMVLDQYQNVGKEVQLGHAENPEYISPR----DFDGHGTHVAATAAGSFVPDTNYLGL 200
Query 214 ------GVAYNARIGGVR--------MLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDD 259
G A ARI + D V+A ++ + + + S S G
Sbjct 201 GRGTARGGAPRARIAMYKACWHLVTGATTCSAADLVKAIDEAIH-DGVDVLSISNGFSVP 259
Query 260 G-KTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSIS 318
VD +A AF G V A GN G + + + + ++++
Sbjct 260 LFPEVDTQDGVAVGAFHAVA------KGIPVVCAGGNAGPSSQTISN----TAPWIITVA 309
Query 319 SATQFGNVPWYSEACSSTLATT---YSSGNQNEKQIVTTDLRQKCTESHTG 366
+ TQ + P + ++ Y + + ++V + E+ G
Sbjct 310 ATTQDRSFPTFITLGNNVTVVGQALYQGPDIDFTELVYPEDSGASNETFYG 360
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 27/125 (22%), Positives = 49/125 (39%), Gaps = 21/125 (17%)
Query 333 CSSTLATTYSSGNQNE--KQIVTTDL-----------------RQKCTESHTGTSASAPL 373
+T T+SS N I+ D+ K +GTS SAP+
Sbjct 458 PVATKVATFSSRGPNSISPAILKPDIAAPGVNILAATSPNDTFYDKGFAMKSGTSMSAPV 517
Query 374 AAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH--SYGYGLLDA 431
AGI+AL + + + ++ +V T+ + +G RK++ YG G++++
Sbjct 518 VAGIVALLKSVHPHWSPAAIRSAIVTTAWRTDPSGEPIFADGSNRKLADPFDYGGGVVNS 577
Query 432 GAMVA 436
Sbjct 578 EKAAN 582
>sp|P26842|CD27_HUMAN CD27 antigen OS=Homo sapiens OX=9606 GN=CD27
PE=1 SV=2
Length=260
Score = 57.1 bits (136), Expect = 1e-07, Method: Composition-based stats.
Identities = 52/242 (21%), Positives = 80/242 (33%), Gaps = 34/242 (14%)
Query 564 TKFTLVLYGTAPEGLPVPPESSGCKT----LTSSQACVVCEEGFSLHQKSCVQHCPPGFA 619
+ L + GT GL P C C +CE G L + C QH
Sbjct 5 HPWWLCVLGTLV-GLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKD-CDQHRKAAQC 62
Query 620 PQVLDTHYSTENDVETIRASVCAPCHAS--CATCQGPALTDCLSCPSHASLDPVEQT-CS 676
+ + + C C++ C A +C +C + E T C
Sbjct 63 DPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAEC-ACRNGWQCRDKECTECD 121
Query 677 R------QSQSSRESPPQQQPPRLPPEVEAGQ--------------RLRAGLLPSHLPEV 716
++SS+ P QP LP E + +L A L +H P
Sbjct 122 PLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPPQ 181
Query 717 VAGLSCAF--IVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSD 774
+ S F I+++F +FLV L + Y ++G + P E CP +
Sbjct 182 RSLCSSDFIRILVIFSGMFLVFTLAGALFLHQRRKYRSNKGESPVE--PAEPCHYSCPRE 239
Query 775 SE 776
E
Sbjct 240 EE 241
>sp|Q9FIM8|SBT4A_ARATH Subtilisin-like protease SBT4.10 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.10 PE=5 SV=1
Length=693
Score = 59.1 bits (141), Expect = 1e-07, Method: Composition-based stats.
Identities = 32/201 (16%), Positives = 64/201 (32%), Gaps = 38/201 (19%)
Query 147 IVVSILDDGIEKNHPDLAGNY------------DPGASFDVNDQ--DPDPQPRYTQMNDN 192
+V + D GI +G G +F N++ +
Sbjct 139 TIVGVFDTGISPESESFSGKGFGPPPKKWKGVCKGGKNFTCNNKLIGARDYTNEGTRDIE 198
Query 193 RHGTRCAGEVAA--VANNGVCGV------GVAYNARIGGVRMLDGEV--TDAVEARSLGL 242
HGT A A V N G+ G ++RI ++ G ++ + +
Sbjct 199 GHGTHTASTAAGNVVENTSFYGIGNGTARGGVPDSRIAAYKVCSGAGCSSEYILSAFDDA 258
Query 243 NPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDS 302
+ + + SAS G + P + G + V ++GN G
Sbjct 259 IADGVDVISASLGGDTAYMYEKDPIAIGAFHAM--------AKGILTVQSAGNNG----- 305
Query 303 CNCDGYTNSIYTLSISSATQF 323
+ + + L+++++T
Sbjct 306 -PNPTVSVAPWILTVAASTTN 325
Score = 52.5 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 23/124 (19%), Positives = 43/124 (35%), Gaps = 14/124 (11%)
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
T+++ P + YS T D R+ +GTS + P
Sbjct 428 NTIAVDILKPDITAP------GVEILAAYSPL--VSPSATTLDNRRVNYTITSGTSMACP 479
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAG 432
+G+ A + +Q ++ T+ P + + D V + + YG G +D
Sbjct 480 HVSGVAAYIKTFHPEWYPSMIQSAIMTTAWPMNPSGTD----AVSTEFA--YGSGHIDPI 533
Query 433 AMVA 436
A +
Sbjct 534 AAIN 537
>sp|G7KEU7|SBT_MEDTR Subtilisin-like protease OS=Medicago truncatula
OX=3880 GN=SBT PE=2 SV=1
Length=748
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 31/213 (15%), Positives = 57/213 (27%), Gaps = 36/213 (17%)
Query 135 KAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN------YDPGASFDVND----------- 177
+ W+ G G+++ I+D GI HP +
Sbjct 129 QGLWSDDNLGKGVIIGIIDTGIFPLHPSFNDEGMPPPPAKWKGHCEFTGGQVCNNKLIGA 188
Query 178 -QDPDPQPRYTQMNDNRHGTRCAGEVAA-------VANNGVCG-VGVAYNARIGGVRMLD 228
+ + HGT A E A V N G+A NA + ++ +
Sbjct 189 RNLVKSAIQEPPFENFFHGTHTAAEAAGRFIEDASVFGNAKGVAAGMAPNAHLAIYKVCN 248
Query 229 GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
++ A + I G E+ G G
Sbjct 249 DKIGCTESAILAA-----MDIAIEDGVDVLSLSLGLGSLPFFEDPIAIGAFAATQN-GVF 302
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
++ N G + + L++ ++T
Sbjct 303 VSCSAANSGPG----YSTLSNEAPWILTVGAST 331
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 13/57 (23%), Positives = 28/57 (49%), Gaps = 0/57 (0%)
Query 352 VTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA 408
V+ D + + +GTS S P +GI AL ++ + + ++ ++ T+ +L
Sbjct 517 VSVDNKIPAFDIVSGTSMSCPHLSGIAALIKSSHPDWSPAAIKSAIMTTANTLNLGG 573
>sp|Q39547|CUCM1_CUCME Cucumisin OS=Cucumis melo OX=3656 PE=1
SV=1
Length=731
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 68/372 (18%), Positives = 109/372 (29%), Gaps = 73/372 (20%)
Query 62 GDYYHFWHRGVTKRSLSPHRPRHSRLQREPQ------VQWLEQQVAKRRTKRDV----YQ 111
D H HR + ++ + S L + V+ E++ K + V
Sbjct 45 PDSAHLHHRAMLEQVVGSTFAPESVLHTYKRSFNGFAVKLTEEEAEKIASMEGVVSVFLN 104
Query 112 EPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG------ 165
E + + W G + IVV +LD GI P
Sbjct 105 EMNELHTTRSWDFLGFP------LTVPRRSQVESNIVVGVLDTGIWPESPSFDDEGFSPP 158
Query 166 ------------------NYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA--- 204
S+ + + P + N HGT A A
Sbjct 159 PPKWKGTCETSNNFRCNRKIIGARSYHI-GRPISPGDVNGPRDTNGHGTHTASTAAGGLV 217
Query 205 -VANNGVCGVGVA----YNARIGGVRM--LDGEVTDAVEARSLGLNPNHIHIYSASWGPE 257
AN G+G A ARI ++ DG + A + + I S S G
Sbjct 218 SQANLYGLGLGTARGGVPLARIAAYKVCWNDGCSDTDILAAYDDAIADGVDIISLSVGGA 277
Query 258 DDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSI 317
P +A G G + ++GNGG + S + LS+
Sbjct 278 -------NPRHYFVDAIAIGSFHAVER-GILTSNSAGNGGPNF----FTTASLSPWLLSV 325
Query 318 SSAT---------QFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTS 368
+++T Q GN + +T Y + + I T + + T S
Sbjct 326 AASTMDRKFVTQVQIGNGQSFQGVSINTFDNQYYPLV-SGRDIPNTGFDKSTSRFCTDKS 384
Query 369 ASAPLAAGIIAL 380
+ L G I +
Sbjct 385 VNPNLLKGKIVV 396
Score = 41.7 bits (96), Expect = 0.025, Method: Composition-based stats.
Identities = 38/223 (17%), Positives = 69/223 (31%), Gaps = 44/223 (20%)
Query 236 EARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGN 295
++ + L I + AS+GP + K++DG A + + R + S+
Sbjct 383 KSVNPNLLKGKIVVCEASFGPHEFFKSLDGAAGVLMTSNTRDYADSYPLPSSVL------ 436
Query 296 GGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQN--EKQIVT 353
D Y SI S S+ + ++SS N K ++
Sbjct 437 -------DPNDLLATLRYIYSIRSPGATIFKSTTILNASAPVVVSFSSRGPNRATKDVIK 489
Query 354 TDLRQKC---------------------TESHTGTSASAPLAAGIIALTLEANKNLTWRD 392
D+ +GTS S P GI N +
Sbjct 490 PDISGPGVEILAAWPSVAPVGGIRRNTLFNIISGTSMSCPHITGIATYVKTYNPTWSPAA 549
Query 393 MQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMV 435
++ ++ T+ P + N + +YG G ++ V
Sbjct 550 IKSALMTTASPMNARFNP--------QAEFAYGSGHVNPLKAV 584
>sp|Q9MAP5|SBT33_ARATH Subtilisin-like protease SBT3.3 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.3 PE=2 SV=1
Length=777
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 50/357 (14%), Positives = 104/357 (29%), Gaps = 82/357 (23%)
Query 64 YYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWY 123
Y H + K + S ++ P+V + + W
Sbjct 74 YRHGFSGFAAKLTKSQA----KKIADLPEVVHVIPDGFHELAT------------TRTWE 117
Query 124 LSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDP-------------- 169
G++ N K G +++ ++D G+ N
Sbjct 118 YLGLSSA--NPKNLLNDTNMGDQVIIGVIDTGVWPESESFNDNGVGPIPRKWKGGCESGE 175
Query 170 ------------GASFDVND--------QDPDPQPRYTQMNDNRHGTRCAGEVAA--VAN 207
GA + +N + + + + + HGT A V N
Sbjct 176 NFRSTDCNRKLIGAKYFINGFLAENKGFNTTESRDYISARDFDGHGTHVASIAGGSFVPN 235
Query 208 NGVCGV------GVAYNARIGGVRM---------LDGEVTDAVEARSLGLNPNHIHIYSA 252
G+ G A ARI + + +D ++A ++ + + + S
Sbjct 236 VSYKGLAGGTLRGGAPRARIAMYKACWFHEELKGVTCSDSDIMKAIDEAIH-DGVDVLSI 294
Query 253 SWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI 312
S G+ + F G+ G + V A GN G + +
Sbjct 295 SL----VGQIPLNSETDIRDEFATGLFHAV-AKGIVVVCAGGNDGPAAQTV----VNIAP 345
Query 313 YTLSISSATQFGNVPWYSEACSSTLA---TTYSSGNQNEKQIVTTDLRQKCTESHTG 366
+ L++++ T + P ++ + TY+ +V + + E+ +G
Sbjct 346 WILTVAATTLDRSFPTPITLGNNKVILGQATYTGPELGLTSLVYPENARNNNETFSG 402
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 19/83 (23%), Positives = 32/83 (39%), Gaps = 2/83 (2%)
Query 356 LRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNG 415
L +GTS + P+ +G+IAL + + + +V T+ G
Sbjct 543 LNVGGFAMLSGTSMATPVISGVIALLKALHPEWSPAAFRSAIVTTAWRTDPFGEQIFAEG 602
Query 416 VGRKVSH--SYGYGLLDAGAMVA 436
RKVS YG G+++
Sbjct 603 SSRKVSDPFDYGGGIVNPEKAAE 625
>sp|Q9FLI4|SBT13_ARATH Subtilisin-like protease SBT1.3 OS=Arabidopsis
thaliana OX=3702 GN=SBT1.3 PE=2 SV=1
Length=780
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 39/238 (16%), Positives = 73/238 (31%), Gaps = 57/238 (24%)
Query 134 VKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG-------------------------NYD 168
+ WA+ T H +VV +LD GI N
Sbjct 135 SERVWAERVTDHDVVVGVLDTGIWPESESFNDTGMSPVPATWRGACETGKRFLKRNCNRK 194
Query 169 PGASFDV-------NDQDPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYN--- 218
+ + + + + + HGT A VA G G AY
Sbjct 195 IVGARVFYRGYEAATGKIDEELEYKSPRDRDGHGTHTAATVAGSPVKGANLFGFAYGTAR 254
Query 219 -----ARIGGVRML---DGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLA 270
AR+ ++ +D + A + + + + S S G G + +
Sbjct 255 GMAQKARVAAYKVCWVGGCFSSDILSAVDQAVA-DGVQVLSISLG--------GGVSTYS 305
Query 271 EEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPW 328
++ + G +G ++GNGG + S S + ++ ++T + P
Sbjct 306 RDSLSIA-TFGAMEMGVFVSCSAGNGGPDPISLTN----VSPWITTVGASTMDRDFPA 358
Score = 47.5 bits (111), Expect = 6e-04, Method: Composition-based stats.
Identities = 20/84 (24%), Positives = 37/84 (44%), Gaps = 3/84 (4%)
Query 349 KQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNA 408
+++D R+ +GTS S P +G+ AL + + + ++ ++ T+ H N
Sbjct 541 PSSLSSDPRRVKFNILSGTSMSCPHVSGVAALIKSRHPDWSPAAIKSALMTTA-YVHDNM 599
Query 409 NDWATNGVGRKVSHSY--GYGLLD 430
T+ G S Y G G +D
Sbjct 600 FKPLTDASGAAPSSPYDHGAGHID 623
>sp|F4KGD4|SBT47_ARATH Subtilisin-like protease SBT4.7 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.7 PE=3 SV=1
Length=703
Score = 58.3 bits (139), Expect = 2e-07, Method: Composition-based stats.
Identities = 69/440 (16%), Positives = 136/440 (31%), Gaps = 72/440 (16%)
Query 1 MELRPWLLWVVAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQI 60
M R + +VV ++ + D Q ++V+ V + P++ H L ++
Sbjct 1 MAKRDYFCFVVLFLSSVSAVIDDPQNKQVYV----VYMGSLPSLLEYTPLSHHMSILQEV 56
Query 61 FGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQ 120
GD + + +RL +++ E + Y+ T +
Sbjct 57 TGD--SSVEGRLVRSYKRSFNGFAARLTESERIRVAEMEGVVSVFPNINYKLQTTASWD- 113
Query 121 QWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNY------------D 168
+L ++ A ++ +D GI +
Sbjct 114 --FLGLKEGKNTKRNLAIE-----SDTIIGFIDSGIWPESESFSDKGFGPPPKKWKGVCS 166
Query 169 PGASFDVNDQ--DPDPQPRYTQMNDNRHGTRCAGEVAAVA---------NNGVCGVGVAY 217
G +F N++ + HGT A A A NG GV
Sbjct 167 GGKNFTCNNKLIGARDYTSEGTRDLQGHGTHTASTAAGNAVADASFFGIGNGTARGGV-P 225
Query 218 NARIGGVRML---DGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAF 274
+RI ++ D + A + + + + S S + P + ++A
Sbjct 226 ASRIAAYKVCSEKDCTAASLLSAFDDAIA-DGVDLISISLAS-------EFPQKYYKDAI 277
Query 275 FRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACS 334
G G + V ++GN G S + + + LS+++ N ++
Sbjct 278 AIGAFH-ANVKGILTVNSAGNSG----SFPSTTASVAPWILSVAA--SNTNRGFF----- 325
Query 335 STLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLT----- 389
T + + + + DL+ K G + + L G I + +
Sbjct 326 -TKVVLGNGKTLVGRSVNSFDLKGKKYPLVYGDNFNESLVQGKI--LVSKFPTSSKVAVG 382
Query 390 ---WRDMQHLVVQTSKPAHL 406
D QH + +SKP L
Sbjct 383 SILIDDYQHYALLSSKPFSL 402
Score = 53.7 bits (127), Expect = 5e-06, Method: Composition-based stats.
Identities = 23/106 (22%), Positives = 40/106 (38%), Gaps = 8/106 (8%)
Query 331 EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTW 390
A + YS ++ +D R+ +GTS S P AG+ A + +
Sbjct 460 SAPGVEILAAYSPLGSPSEE--ESDKRRVKYSVMSGTSMSCPHVAGVAAYIRTFHPKWSP 517
Query 391 RDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
+Q ++ T+ P N +A+ YG G +D A +
Sbjct 518 SVIQSAIMTTAWPMKPNRPGFASTEFA------YGAGHVDQIAAIN 557
>sp|P0DD35|C5AP_STRPQ C5a peptidase OS=Streptococcus pyogenes
serotype M3 (strain SSI-1) OX=193567 GN=scpA PE=3 SV=1
Length=1169
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 55/293 (19%), Positives = 93/293 (32%), Gaps = 48/293 (16%)
Query 96 LEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLN----VKAAWAQGYTGHGIVVSI 151
E+ VA + P S T RDLN VK + G G VV++
Sbjct 74 AEETVADKANDLAPQAPAKTADIPAT---SKETIRDLNDPSHVKTLQEKAGKGAGTVVAV 130
Query 152 LDDGIEKNH----------------PDL-AGNYDPGASF-----DVNDQDPDPQPRYTQM 189
+D G +KNH DL D G ++ D D
Sbjct 131 IDAGFDKNHEAWRLTDKSKARYQSKEDLEKAKKDHGITYGEWVNDKVAYYHDYSKDGKTA 190
Query 190 NDNRHGTRCAGEVAAVANNGVC----GVGVAYNARIGGVRM-----LDGEVTDAVEARSL 240
D HGT +G ++ A + G A++ +R+ L + +A
Sbjct 191 VDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRD 250
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
+N + + S+G + ++AF G V ++GN
Sbjct 251 AVNL-GAKVINMSFG--NAALAYANLPDETKKAFDYA-----KSKGVSIVTSAGNDSSFG 302
Query 301 DSC--NCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQI 351
+ + + ++A V YS T T + +Q +K++
Sbjct 303 GKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEM 355
Score = 48.7 bits (114), Expect = 3e-04, Method: Composition-based stats.
Identities = 55/325 (17%), Positives = 105/325 (32%), Gaps = 44/325 (14%)
Query 198 CAGEVAAVANNGVCGVGVAYNARI---GGVRMLDGEVTDAVEARSLGLNPNHIHIYSAS- 253
G AA A++ + + + ++ V+ D + + + PN + Y+ +
Sbjct 317 VVGTPAA-ADSTLTVASYSPDKQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYAN 375
Query 254 -WGPEDDGKTVDGPARLAEEAFF----RGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY 308
EDD K V G L E + + + G + ++ + + G + N D
Sbjct 376 RGTKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQM 435
Query 309 T--------------NSIYTLSISSA------TQFGNVPWYSEACSSTLATTYSSGNQNE 348
NS T++ ++ + +S +
Sbjct 436 PAAFISRKDGLLLKDNSKKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPG 495
Query 349 KQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE----ANKNLTWRDMQHLVVQTSKPA 404
+ I+++ K +GTS SAPL AGI+ L + ++T + L K
Sbjct 496 QDILSSVANNK-YAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDL---AKKVL 551
Query 405 HLNANDWATNGVGRKVSH-SYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGK 463
+A S G G +DA + A + T + + +
Sbjct 552 MSSATALYDEDEKAYFSPRQQGAGAVDAKKA-SAATMYVTDKDNTSSKVHLNN----VSD 606
Query 464 RLEVRKTVTACLGEPNHITRLEHAQ 488
+ EV TV +P + Q
Sbjct 607 KFEVTVTVHNKSDKPQELYYQATVQ 631
>sp|P0DD34|C5AP_STRP3 C5a peptidase OS=Streptococcus pyogenes
serotype M3 (strain ATCC BAA-595 / MGAS315) OX=198466 GN=scpA
PE=3 SV=1
Length=1169
Score = 58.7 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 55/293 (19%), Positives = 93/293 (32%), Gaps = 48/293 (16%)
Query 96 LEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLN----VKAAWAQGYTGHGIVVSI 151
E+ VA + P S T RDLN VK + G G VV++
Sbjct 74 AEETVADKANDLAPQAPAKTADIPAT---SKETIRDLNDPSHVKTLQEKAGKGAGTVVAV 130
Query 152 LDDGIEKNH----------------PDL-AGNYDPGASF-----DVNDQDPDPQPRYTQM 189
+D G +KNH DL D G ++ D D
Sbjct 131 IDAGFDKNHEAWRLTDKSKARYQSKEDLEKAKKDHGITYGEWVNDKVAYYHDYSKDGKTA 190
Query 190 NDNRHGTRCAGEVAAVANNGVC----GVGVAYNARIGGVRM-----LDGEVTDAVEARSL 240
D HGT +G ++ A + G A++ +R+ L + +A
Sbjct 191 VDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRD 250
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
+N + + S+G + ++AF G V ++GN
Sbjct 251 AVNL-GAKVINMSFG--NAALAYANLPDETKKAFDYA-----KSKGVSIVTSAGNDSSFG 302
Query 301 DSC--NCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQI 351
+ + + ++A V YS T T + +Q +K++
Sbjct 303 GKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEM 355
Score = 48.7 bits (114), Expect = 3e-04, Method: Composition-based stats.
Identities = 55/325 (17%), Positives = 105/325 (32%), Gaps = 44/325 (14%)
Query 198 CAGEVAAVANNGVCGVGVAYNARI---GGVRMLDGEVTDAVEARSLGLNPNHIHIYSAS- 253
G AA A++ + + + ++ V+ D + + + PN + Y+ +
Sbjct 317 VVGTPAA-ADSTLTVASYSPDKQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYAN 375
Query 254 -WGPEDDGKTVDGPARLAEEAFF----RGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY 308
EDD K V G L E + + + G + ++ + + G + N D
Sbjct 376 RGTKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQM 435
Query 309 T--------------NSIYTLSISSA------TQFGNVPWYSEACSSTLATTYSSGNQNE 348
NS T++ ++ + +S +
Sbjct 436 PAAFISRKDGLLLKDNSKKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPG 495
Query 349 KQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLE----ANKNLTWRDMQHLVVQTSKPA 404
+ I+++ K +GTS SAPL AGI+ L + ++T + L K
Sbjct 496 QDILSSVANNK-YAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDL---AKKVL 551
Query 405 HLNANDWATNGVGRKVSH-SYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGK 463
+A S G G +DA + A + T + + +
Sbjct 552 MSSATALYDEDEKAYFSPRQQGAGAVDAKKA-SAATMYVTDKDNTSSKVHLNN----VSD 606
Query 464 RLEVRKTVTACLGEPNHITRLEHAQ 488
+ EV TV +P + Q
Sbjct 607 KFEVTVTVHNKSDKPQELYYQATVQ 631
>sp|Q8GWX9|SBT3G_ARATH Subtilisin-like protease SBT3.16 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.16 PE=2 SV=1
Length=759
Score = 58.3 bits (139), Expect = 2e-07, Method: Composition-based stats.
Identities = 56/367 (15%), Positives = 106/367 (29%), Gaps = 87/367 (24%)
Query 11 VAATGTLVLLAADAQGQKVFTNTWAVRIPGGPAVANSVARKHGFLNLGQIFGD------- 63
+ + L+ A + +++T V + ++ + LG + G
Sbjct 22 LVLIFKIALITAANEKSQIYT----VHLGERQHDDPNIVTESHHDILGPLLGSKKASHES 77
Query 64 -YYHFWHRGVTKRS-LSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQ 121
Y + H + L+ + R L P V R R + +
Sbjct 78 MIYSYRHGFSGFAAKLTSSQARE--LSGHPDV---------VRVTRSKNMKLKTTRVSDY 126
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDP------------ 169
L+ L G +V ILD GI + N
Sbjct 127 LGLTSAAPTGL----LHETDM-GSEAIVGILDSGIWPDSKSFNDNGLGPIPTRWKGKCVS 181
Query 170 -----------------------GASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA-- 204
+ ++ + + + ++ HGT CA
Sbjct 182 AEAFNASSCNRKLIGAMYYSKGLESKYNGSFNAAEKGEVMSPLDKIGHGTHCASTAVGSF 241
Query 205 VANNGVCGV------GVAYNARIGGVRML----DGEVTDAVEARSLGLNPNHIHIYSASW 254
V + V + G A ARI ++ + D V+A + + + + S S
Sbjct 242 VPDANVLSLAQGTARGSAPRARIASYKVCWNNEECFTPDIVKAIDHAI-RDGVDVLSLSL 300
Query 255 GPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYT 314
G E A AF + G V A GN G E ++ + + +
Sbjct 301 GSEVPVDFEVDRDDFAIAAFHAVM------KGIPVVCAGGNDGPEKETISN----VAPWL 350
Query 315 LSISSAT 321
+++++ T
Sbjct 351 ITVAATT 357
Score = 55.2 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 23/110 (21%), Positives = 45/110 (41%), Gaps = 4/110 (4%)
Query 325 NVPWYSEACSSTLATTY--SSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTL 382
V +S ++L+ I+ + +GTS S P+ +GI+AL
Sbjct 494 KVARFSSRGPNSLSPVILKPDIAAPGSGILAAVPTGGGYDFMSGTSMSTPVVSGIVALLR 553
Query 383 EANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH--SYGYGLLD 430
+ + + ++ +V T+ + A G RK++ YG GL++
Sbjct 554 KKRPDWSPAAIRSALVTTALQTDPSGEPIAAEGSPRKLADPFDYGGGLVN 603
>sp|F4JJH4|SBT31_ARATH Subtilisin-like protease SBT3.1 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.1 PE=3 SV=2
Length=764
Score = 57.9 bits (138), Expect = 3e-07, Method: Composition-based stats.
Identities = 61/381 (16%), Positives = 112/381 (29%), Gaps = 83/381 (22%)
Query 66 HFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQW-YL 124
+ +H G + + +L++ P+V + K + + W YL
Sbjct 81 YSYHHGFSGFAAKLKPAEAEKLKKHPEVI-----ILLENRKLGLQT-------TRTWDYL 128
Query 125 SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGN------------------ 166
+ + G G ++ ++D GI +
Sbjct 129 GQFSTPTSSKSLLHETNM-GSGAIIGVIDSGIWSESGSFDDDGYGPIPKHWKGQCVSADQ 187
Query 167 ---------------YDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA--VAN-- 207
Y G + D+ + + N HGT+ + A V+N
Sbjct 188 FSPADCNKKLIGAKYYIDGLNADLETSINSTTEYLSPRDHNGHGTQVSSTAAGSFVSNMT 247
Query 208 -----NGVCGVGVAYNARIGGVR----MLDG--EVTDAVEARSLGLNPNHIHIYSASWGP 256
+G G A A I + + G V D +A ++ + + + S S G
Sbjct 248 LLGLSSGSIMRGGAPKAHIAMYKACWDVEGGMCSVADVWKAFDEAIH-DGVDVLSVSVGG 306
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLS 316
KT+D +A A G V +GN G S S + L+
Sbjct 307 -SALKTLDVEIDIAIPALHAV------NKGIPVVSPAGNEGSRSSSV----INVSPWILT 355
Query 317 ISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAG 376
+++ T + + T +I TD+ CT H+ + G
Sbjct 356 VAATTLD--RSFSTLITLENNKTYLGQSLYTGPEISFTDVI--CTGDHSNVDQ---ITKG 408
Query 377 IIALTLEANKN--LTWRDMQH 395
+ + LT +Q
Sbjct 409 KVIMHFSMGPVRPLTPDVVQK 429
Score = 53.7 bits (127), Expect = 7e-06, Method: Composition-based stats.
Identities = 26/132 (20%), Positives = 48/132 (36%), Gaps = 3/132 (2%)
Query 307 GYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTG 366
Y I S + S + + + G + TD + ++G
Sbjct 481 PYKTIIGESVASKVAKSSARGPSSFSPAILKPDIAAPGLTLLTPRIPTDEDTR-EFVYSG 539
Query 367 TSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH--SY 424
TS + P+ AGI+AL ++ N + ++ +V T+ +G KV+ Y
Sbjct 540 TSMATPVIAGIVALLKISHPNWSPAVIKSALVTTAMKTDPYGERLTVDGGNYKVADAFDY 599
Query 425 GYGLLDAGAMVA 436
G GL++
Sbjct 600 GGGLVNLEKATD 611
>sp|P58099|C5AP_STRP1 C5a peptidase OS=Streptococcus pyogenes
serotype M1 OX=301447 GN=scpA PE=1 SV=1
Length=1181
Score = 57.9 bits (138), Expect = 3e-07, Method: Composition-based stats.
Identities = 53/293 (18%), Positives = 92/293 (31%), Gaps = 48/293 (16%)
Query 96 LEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLN----VKAAWAQGYTGHGIVVSI 151
E+ +A P S T RDLN VK + G G VV++
Sbjct 72 AEETIADDANDLAPQAPAKTADTPAT---SKATIRDLNDPSQVKTLQEKAGKGAGTVVAV 128
Query 152 LDDGIEKNH----------------PDL-AGNYDPGASF-----DVNDQDPDPQPRYTQM 189
+D G +KNH DL + G ++ D D
Sbjct 129 IDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTA 188
Query 190 NDNRHGTRCAGEVAAVANNGVC----GVGVAYNARIGGVRM-----LDGEVTDAVEARSL 240
D HGT +G ++ A + G A++ +R+ L + +A
Sbjct 189 VDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIID 248
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
+N + + S+G + ++AF G V ++GN
Sbjct 249 AVNL-GAKVINMSFG--NAALAYANLPDETKKAFDYA-----KSKGVSIVTSAGNDSSFG 300
Query 301 DSC--NCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQI 351
+ + + ++A V YS T T + +Q +K++
Sbjct 301 GKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEM 353
Score = 46.7 bits (109), Expect = 9e-04, Method: Composition-based stats.
Identities = 31/174 (18%), Positives = 54/174 (31%), Gaps = 14/174 (8%)
Query 320 ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIA 379
+ +S + + I+++ K +GTS SAPL AGI+
Sbjct 465 TASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNK-YAKLSGTSMSAPLVAGIMG 523
Query 380 LTLE----ANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH-SYGYGLLDAGAM 434
L + ++T + L K +A S G G +DA
Sbjct 524 LLQKQYETQYPDMTPSERLDL---AKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKA 580
Query 435 VALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQ 488
+ A + T + + + + EV TV +P + Q
Sbjct 581 -SAATMYVTDKDNTSSKVHLNN----VSDKFEVTVTVHNKSDKPQELYYQATVQ 629
>sp|Q8NZ80|C5AP_STRP8 C5a peptidase OS=Streptococcus pyogenes
serotype M18 (strain MGAS8232) OX=186103 GN=scpA PE=3 SV=1
Length=1150
Score = 57.9 bits (138), Expect = 3e-07, Method: Composition-based stats.
Identities = 54/293 (18%), Positives = 94/293 (32%), Gaps = 48/293 (16%)
Query 96 LEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLN----VKAAWAQGYTGHGIVVSI 151
E+ VA + + P S T RDLN VK + G G VV++
Sbjct 72 AEETVADKANDLALQAPAKTADTPAT---SKATIRDLNDPSQVKTLQEKAGKGAGTVVAV 128
Query 152 LDDGIEKNH----------------PDL-AGNYDPGASF-----DVNDQDPDPQPRYTQM 189
+D G +KNH DL + G ++ D D
Sbjct 129 IDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTA 188
Query 190 NDNRHGTRCAGEVAAVANNGVC----GVGVAYNARIGGVRM-----LDGEVTDAVEARSL 240
D HGT +G ++ A + G A++ +R+ L + +A
Sbjct 189 VDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRD 248
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
+N + + S+G + ++AF G V ++GN
Sbjct 249 AVNL-GAKVINMSFG--NAALAYANLPDETKKAFDYA-----KSKGVSIVTSAGNDSSFG 300
Query 301 DSC--NCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQI 351
+ + + ++A V YS T T + +Q +K++
Sbjct 301 GKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEM 353
Score = 47.1 bits (110), Expect = 7e-04, Method: Composition-based stats.
Identities = 31/174 (18%), Positives = 54/174 (31%), Gaps = 14/174 (8%)
Query 320 ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIA 379
+ +S + + I+++ K +GTS SAPL AGI+
Sbjct 465 TASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNK-YAKLSGTSMSAPLVAGIMG 523
Query 380 LTLE----ANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH-SYGYGLLDAGAM 434
L + ++T + L K +A S G G +DA
Sbjct 524 LLQKQYEIQYPDMTPSERLDL---AKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKA 580
Query 435 VALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQ 488
+ A + T + + + + EV TV +P + Q
Sbjct 581 -SAATMYVTDKDNTSSKVHLNN----VSDKFEVTVTVHNKSDKPQELYYQATVQ 629
>sp|F4HPF1|SBT34_ARATH Subtilisin-like protease SBT3.4 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.4 PE=3 SV=1
Length=773
Score = 57.5 bits (137), Expect = 4e-07, Method: Composition-based stats.
Identities = 51/356 (14%), Positives = 101/356 (28%), Gaps = 81/356 (23%)
Query 64 YYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWY 123
Y H + K + S ++ P+V + Y+ T + W
Sbjct 71 YRHGFSGFAAKLTKSQA----KKIADSPEVIHVIPD--------SYYELAT----TRIWD 114
Query 124 LSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG------------------ 165
G + N K + G ++ ++D G+
Sbjct 115 YLGPSAD--NSKNLVSDTNMGDQTIIGVIDTGVWPESESFNDYGVGPVPSHWKGGCEPGE 172
Query 166 NYDP--------GASFDVND-------QDPDPQPRYTQMNDNRHGTRCAGEVAA--VANN 208
N+ GA + +N + + + + HGT A V N
Sbjct 173 NFISTNCNRKLIGAKYFINGFLAENQFNATESPDYISARDFDGHGTHVASIAGGSFVPNV 232
Query 209 GVC------GVGVAYNARIGGVRM------LDG---EVTDAVEARSLGLNPNHIHIYSAS 253
G A ARI + LDG +D ++A ++ + + + S S
Sbjct 233 SYKGLGRGTLRGGAPRARIAMYKACWYINELDGVTCSFSDIMKAIDEAIH-DGVDVLSIS 291
Query 254 WGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIY 313
G G+ + G G + V A GN G + + +
Sbjct 292 LG----GRVPLNSETDLRDGIATGAFHAV-AKGIVVVCAGGNAGPSSQTV----VNTAPW 342
Query 314 TLSISSATQFGNVPWYSEACSSTLA---TTYSSGNQNEKQIVTTDLRQKCTESHTG 366
L++++ T + ++ + Y +V + ++ +G
Sbjct 343 ILTVAATTLDRSFATPIILGNNQVILGQAMYIGPELGFTSLVYPEDPGNSIDTFSG 398
Score = 50.2 bits (118), Expect = 6e-05, Method: Composition-based stats.
Identities = 43/237 (18%), Positives = 66/237 (28%), Gaps = 34/237 (14%)
Query 229 GEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
G D LN N + + + + GGLG I
Sbjct 390 GNSIDTFSGVCESLNLNSNRTMAGKV-----VLCFTTARDFTVVSTAASIVKAAGGLGLI 444
Query 289 FVWASG-NGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSE-------ACSSTLATT 340
G N D C N + T + G+ + T T
Sbjct 445 IARNPGYNLAPCSDDFPCVAIDNELGTDILFYIRYTGSPVVKIQPSRTLVGEPVGTKVAT 504
Query 341 YSSGNQNE--KQIVTTD-----------------LRQKCTESHTGTSASAPLAAGIIALT 381
+SS N I+ D L +GTS +AP+ +G+IAL
Sbjct 505 FSSRGPNSISPAILKPDIAAPGVSILAATSPNDTLNAGGFVMRSGTSMAAPVISGVIALL 564
Query 382 LEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH--SYGYGLLDAGAMVA 436
+ + + + +V T+ A KV YG GL++
Sbjct 565 KSLHPDWSPAAFRSAIVTTAWRTDPFGEQIAAESSSLKVPDPFDYGGGLVNPEKAAE 621
>sp|Q9C7U8|SBT3H_ARATH Subtilisin-like protease SBT3.17 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.17 PE=3 SV=1
Length=753
Score = 57.5 bits (137), Expect = 4e-07, Method: Composition-based stats.
Identities = 48/319 (15%), Positives = 90/319 (28%), Gaps = 77/319 (24%)
Query 57 LGQIFGDYYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDP 116
+ +Y H + K + S + L P+V + R
Sbjct 72 KNSLVYNYKHGFSGFAAKLTASQAKN----LSAHPEVLRVVPSRVMRLKT---------T 118
Query 117 KFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDL------------A 164
+ L + + L + G ++ ++D GI
Sbjct 119 RTFDYLGLLPTSPKSLL-----HKTKMGSEAIIGVIDSGIWPESQSFNDTGLGPIPKRWK 173
Query 165 GNYDPGASFDVNDQ------------------------DPDPQPRYTQMNDNRHGTRCAG 200
G G FD P + + HGT A
Sbjct 174 GKCLSGNGFDAKKHCNKKLIGAEYLTVGLMEMTDGIYDYPSLGESMSPRDHVGHGTHVAA 233
Query 201 EVAA--VANNGVCGV------GVAYNARIGGVRM----LDGEVTDAVEARSLGLNPNHIH 248
A VAN G+ G A +ARI ++ + D ++A + + +
Sbjct 234 IAAGSFVANANYKGLAGGTARGAAPHARIAMYKVCWREVGCITADLLKAIDHSI-RDGVD 292
Query 249 IYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY 308
+ S S G D + D F V G V ++GN G + +
Sbjct 293 VISISIG-TDAPASFDIDQSDIGFGSFHAVM-----KGIPVVASAGNEGPNAQTVDN--- 343
Query 309 TNSIYTLSISSATQFGNVP 327
+ + +++++ + + P
Sbjct 344 -VAPWIITVAATSLDRSFP 361
Score = 49.8 bits (117), Expect = 9e-05, Method: Composition-based stats.
Identities = 16/78 (21%), Positives = 36/78 (46%), Gaps = 2/78 (3%)
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
+ +GTS + P +GI+ L + + + + ++ +V T+ + + G RK+
Sbjct 527 YKFMSGTSMATPAVSGIVGLLRQTHPHWSPAAIRSALVTTAWKTDPSGEPIFSEGSTRKL 586
Query 421 SH--SYGYGLLDAGAMVA 436
+ YG GL++ +
Sbjct 587 ADPFDYGGGLINPEKVTH 604
>sp|Q5X9R0|C5AP_STRP6 C5a peptidase OS=Streptococcus pyogenes
serotype M6 (strain ATCC BAA-946 / MGAS10394) OX=286636 GN=scpA
PE=3 SV=1
Length=1184
Score = 57.5 bits (137), Expect = 5e-07, Method: Composition-based stats.
Identities = 54/293 (18%), Positives = 93/293 (32%), Gaps = 48/293 (16%)
Query 96 LEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLN----VKAAWAQGYTGHGIVVSI 151
E+ VA + P S T RDLN VK + G G VV++
Sbjct 72 AEETVADKANDLAPQAPAKTTDTPAT---SKATIRDLNDPSQVKTLQEKAGKGAGTVVAV 128
Query 152 LDDGIEKNH----------------PDL-AGNYDPGASF-----DVNDQDPDPQPRYTQM 189
+D G +KNH DL + G ++ D D
Sbjct 129 IDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKIAYYHDYSKDGKTA 188
Query 190 NDNRHGTRCAGEVAAVANNGVC----GVGVAYNARIGGVRM-----LDGEVTDAVEARSL 240
D HGT +G ++ A + G A++ +R+ L + +A
Sbjct 189 VDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRD 248
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
+N + + S+G + ++AF G V ++GN
Sbjct 249 AVNL-GAKVINMSFG--NAALAYANLPDETKKAFDYA-----KSKGVSIVTSAGNDSSFG 300
Query 301 DSC--NCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQI 351
+ + + ++A V YS T T + +Q +K++
Sbjct 301 GKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEM 353
Score = 47.1 bits (110), Expect = 8e-04, Method: Composition-based stats.
Identities = 31/174 (18%), Positives = 53/174 (30%), Gaps = 14/174 (8%)
Query 320 ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIA 379
+ +S + + I+++ K +GTS SAPL AGI+
Sbjct 465 TASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNK-YAKLSGTSMSAPLVAGIMG 523
Query 380 LTLE----ANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH-SYGYGLLDAGAM 434
L + ++T + L K +A S G G +DA
Sbjct 524 LLQKQYETQYPDMTPSERLDL---AKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKA 580
Query 435 VALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQ 488
+ A + T + + + EV TV +P + Q
Sbjct 581 -SAATMYVTDKDNTSSKVHLNN----VSDTFEVTVTVHNKSDKPQELYYQATVQ 629
>sp|I1N462|SBT1_SOYBN Subtilisin-like protease Glyma18g48580 OS=Glycine
max OX=3847 GN=Glyma18g48580 PE=1 SV=3
Length=789
Score = 56.7 bits (135), Expect = 6e-07, Method: Composition-based stats.
Identities = 63/410 (15%), Positives = 129/410 (31%), Gaps = 87/410 (21%)
Query 8 LWVVAATGTLVLLAADAQGQKVFTNTWAVRIPG-GPAVAN-SVARKHGFLNLGQIFGD-- 63
L + + LLAA +K + G P A+ +A + LG IFG
Sbjct 10 LILSSFFLFTFLLAAVNGSKKCYIVYMGAHSHGPSPTSADLELATDSHYDLLGSIFGSRE 69
Query 64 -----YYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKF 118
+ ++R + + + + + P V + +
Sbjct 70 KAKEAIIYSYNRHINGFAALLEEEEAADIAKNPNVVSVFLSKEHK------------LHT 117
Query 119 PQQWYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG--------NYDPG 170
+ W G+ +R N +AW +G G ++ +D G+ + + G
Sbjct 118 TRSWEFLGLHRRGQN--SAWQKGRFGENTIIGNIDTGVWPESQSFSDKGYGTVPSKWRGG 175
Query 171 --------------------------ASFDVNDQDPDPQPRYTQMNDNRHGTR---CAG- 200
+F+ ++ DP +T + HGT AG
Sbjct 176 LCQINKLPGSMKNTCNRKLIGARYYNKAFEAHNGQLDPL-LHTARDFVGHGTHTLSTAGG 234
Query 201 ------EVAAVANNGVCGVGVAYNARIGGVRML-------DGEVTDAVEARSLGLNPNHI 247
V AV N G + AR+ ++ D + A ++ + +
Sbjct 235 NFVPGARVFAVGNGT--AKGGSPRARVAAYKVCWSLTDPASCYGADVLAAIDQAID-DGV 291
Query 248 HIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDG 307
+ + S+G T +G + + G + V ++GN G +
Sbjct 292 DVINVSFG-VSYVVTAEG---IFTDEISIGAFHAI-SKNILLVASAGNDGPTPGTVAN-- 344
Query 308 YTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNE--KQIVTTD 355
++T++ S+ + + A+ + + N+ I++TD
Sbjct 345 VAPWVFTIAASTLDRDFSSNLTINNQLIEGASLFVNLPPNQAFSLILSTD 394
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 26/199 (13%), Positives = 57/199 (29%), Gaps = 13/199 (7%)
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWR 391
A + YS +V + R GTS S P A+GI L + + +
Sbjct 541 APGVNILAAYSEFASASSLLVD-NRRGFKFNVLQGTSMSCPHASGIAGLLKTRHPSWSPA 599
Query 392 DMQHLVVQTSKPAHLNANDWATN-GVGRKVSHSYGYGLLDAGAMVALAQNW-TTVAPQRK 449
++ ++ T+ + +YG G + + + ++
Sbjct 600 AIKSAIMTTATTLDNTNRPIQDAFDKTLADAFAYGSGHVRPDLAIEPGLVYDLSLTDYLN 659
Query 450 CIIDILTEPKDIGKRLEVRKTVTACLGEPNHITR---------LEHAQARLTLSYNRRGD 500
+ + + I R + + N + L+ T++
Sbjct 660 FLCASGYDQQLISALNFNRTFICSGSHSVNDLNYPSITLPNLRLKPVTIARTVTNVGPPS 719
Query 501 L-AIHLVSPMGTRSTLLAA 518
+ SP G ++
Sbjct 720 TYTVSTRSPNGYSIAVVPP 738
>sp|P15926|C5AP_STRPY C5a peptidase OS=Streptococcus pyogenes
OX=1314 GN=scpA PE=1 SV=1
Length=1167
Score = 56.7 bits (135), Expect = 8e-07, Method: Composition-based stats.
Identities = 62/361 (17%), Positives = 106/361 (29%), Gaps = 62/361 (17%)
Query 96 LEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLN----VKAAWAQGYTGHGIVVSI 151
E+ +A P S T RDLN VK + G G VV++
Sbjct 72 AEETIADDANDLAPQAPAKTADTPAT---SKATIRDLNDPSQVKTLQEKAGKGAGTVVAV 128
Query 152 LDDGIEKNH----------------PDL-AGNYDPGASF-----DVNDQDPDPQPRYTQM 189
+D G +KNH DL + G ++ D D
Sbjct 129 IDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTA 188
Query 190 NDNRHGTRCAGEVAAVANNGVC----GVGVAYNARIGGVRM-----LDGEVTDAVEARSL 240
D HGT +G ++ A + G A++ +R+ L + +A
Sbjct 189 VDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRD 248
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH 300
+N + + S+G + ++AF G V ++GN
Sbjct 249 AVNL-GAKVINMSFG--NAALAYANLPDETKKAFDYA-----KSKGVSIVTSAGNDSSFG 300
Query 301 DSC--NCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQ 358
+ + + ++A V YS E +V TD +Q
Sbjct 301 GKTRLPLADHPDYGVVGTPAAADSTLTVASYS-----------PDKQLTETAMVKTDDQQ 349
Query 359 KCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQ---HLVVQTSKPAHLNANDWATNG 415
T+ P A A K ++D++ L+ + + G
Sbjct 350 DKEMPVLSTNRFEPNKAYDYAYANRGMKEDDFKDVKGKIALIERGDIDFKDKVANAKKAG 409
Query 416 V 416
Sbjct 410 A 410
Score = 46.7 bits (109), Expect = 8e-04, Method: Composition-based stats.
Identities = 31/174 (18%), Positives = 54/174 (31%), Gaps = 14/174 (8%)
Query 320 ATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIA 379
+ +S + + I+++ K +GTS SAPL AGI+
Sbjct 465 TASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNK-YAKLSGTSMSAPLVAGIMG 523
Query 380 LTLE----ANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH-SYGYGLLDAGAM 434
L + ++T + L K +A S G G +DA
Sbjct 524 LLQKQYETQYPDMTPSERLDL---AKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKA 580
Query 435 VALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQ 488
+ A + T + + + + EV TV +P + Q
Sbjct 581 -SAATMYVTDKDNTSSKVHLNN----VSDKFEVTVTVHNKSDKPQELYYQATVQ 629
>sp|Q8GUK4|SBT3D_ARATH Subtilisin-like protease SBT3.13 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.13 PE=2 SV=1
Length=766
Score = 56.4 bits (134), Expect = 8e-07, Method: Composition-based stats.
Identities = 60/392 (15%), Positives = 115/392 (29%), Gaps = 92/392 (23%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
Y + H +L + ++ P+V + ++ + L
Sbjct 81 YSYQHGFSGFAALLTSS-QAKKISEHPEVIHVIPNRIRKLKT---------TRAWDHLGL 130
Query 125 SGVT---QRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG---------------- 165
S + +VK G ++ ++D GI +
Sbjct 131 SPIPTSFSSLSSVKGLLHDTNLGSEAIIGVIDSGIWPESKAVNDQGLGPIPKRWRGKCEP 190
Query 166 -----------NYDPGASFDVND---------QDPDPQPRYTQMNDNRHGTRCAGEVAA- 204
N GA + +N Q + + N HGT A +A
Sbjct 191 GEQFNATIHCNNKLIGARYYLNGVVAAIGGKFNRTIIQDFQSTRDANGHGTHTA-TIAGG 249
Query 205 --VANNGVCGV------GVAYNARIGGVRM-----------LDGEVT--DAVEARSLGLN 243
V N G+ G A ARI + DG T D +A ++
Sbjct 250 SFVPNVSYFGLAQGLVRGGAPRARIASYKACWNVMRDEGGGTDGRCTSADMWKAFDDAIH 309
Query 244 PNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSC 303
+ + + S S G P + + G V A+GN G +
Sbjct 310 -DGVDVLSVSIGG-------GIPEDSEVDKLDYIAAFHAVAKGITVVAAAGNEGPGAHTV 361
Query 304 NCDGYTNSIYTLSISSATQFGNVPWYSEACSST--LATTYSSGNQNEKQIVTTDLRQKCT 361
+ + + L++++ T + P ++ A + +G + + D T
Sbjct 362 DN----VAPWLLTVAATTLDRSFPTKITLGNNQTLFAESLFTGPEISTGLAFLDSDSDDT 417
Query 362 ESHTGTS-----ASAPLAA-GIIALTLEANKN 387
G + ++ P+A G+ A+ L +
Sbjct 418 VDVKGKTVLVFDSATPIAGKGVAAVILAQKPD 449
Score = 50.2 bits (118), Expect = 7e-05, Method: Composition-based stats.
Identities = 19/81 (23%), Positives = 34/81 (42%), Gaps = 2/81 (2%)
Query 358 QKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVG 417
Q +GTS S P+ +GIIAL + + ++ +V T+ + G
Sbjct 539 QNGFGLLSGTSMSTPVVSGIIALLKSLHPKWSPAAVRSALVTTAWRTSPSGEPIFAEGSN 598
Query 418 RKVSH--SYGYGLLDAGAMVA 436
+K++ YG GL++
Sbjct 599 KKLADPFDYGGGLVNPEKAAK 619
>sp|F4JA91|SBT45_ARATH Subtilisin-like protease SBT4.5 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.5 PE=3 SV=1
Length=738
Score = 56.4 bits (134), Expect = 9e-07, Method: Composition-based stats.
Identities = 44/251 (18%), Positives = 76/251 (30%), Gaps = 61/251 (24%)
Query 147 IVVSILDDGIEKNHPDLAGNY------------DPGASFDVNDQ-----------DPDPQ 183
++ ++D GI +G G +F N++ + P+
Sbjct 138 TIIGVIDSGIYPESDSFSGKGFGPPPKKWKGVCKGGKNFTWNNKLIGARYYTPKLEGFPE 197
Query 184 PRYTQMNDNRHGTRCAGEVAAVA---------NNGVCGVGVAYNARIGGVRM----LDGE 230
M HG+ A A A NG GV ARI ++ +DG
Sbjct 198 SARDYM---GHGSHTASTAAGNAVKHVSFYGLGNGTARGGV-PAARIAVYKVCDPGVDGC 253
Query 231 VTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFV 290
TD + A + + I + S G ++ + P + G + V
Sbjct 254 TTDGILAAFDDAIADKVDIITISIGGDNSSPFEEDPIAIGAFHAM--------AKGILIV 305
Query 291 WASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQ 350
++GN G E + SI + A N + +G +
Sbjct 306 NSAGNSGPEPSTVA------SIAPWMFTVAASNTNRAF-------VTKVVLGNGKTVGRS 352
Query 351 IVTTDLRQKCT 361
+ + DL K
Sbjct 353 VNSFDLNGKKY 363
Score = 51.7 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 23/103 (22%), Positives = 35/103 (34%), Gaps = 17/103 (17%)
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWR 391
A S + YS +D R+ TGTS S P AG+ A + +
Sbjct 495 APGSEIVAAYSPDAPPSI----SDTRRVKYSVDTGTSMSCPHVAGVAAYLKSFHPRWSPS 550
Query 392 DMQHLVVQTSKPAHLNANDWATNGVGRKVSHS----YGYGLLD 430
+Q ++ T+ W N + YG G +D
Sbjct 551 MIQSAIMTTA---------WPMNASTSPFNELAEFAYGAGHVD 584
>sp|Q9SZY3|SBT38_ARATH Subtilisin-like protease SBT3.8 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.8 PE=3 SV=1
Length=775
Score = 56.4 bits (134), Expect = 1e-06, Method: Composition-based stats.
Identities = 54/356 (15%), Positives = 103/356 (29%), Gaps = 80/356 (22%)
Query 66 HFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLS 125
H + G + + + + +L P+V + YQ T + W
Sbjct 70 HSYRHGFSGFAAKLTKSQAKKLADLPEVVHVTPD--------SFYQLDT----TRTWDYL 117
Query 126 GVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDP---------------- 169
G++ N K G +++ I+D G+ N
Sbjct 118 GLSVA--NPKNLLNDTNMGEEVIIGIVDSGVWPESEVFNDNGIGPVPSHWKGGCVSGENF 175
Query 170 ----------GASFDVND--------QDPDPQPRYTQMNDNRHGTRCAGEVAA---VANN 208
GA + +N + + + + HGT A +A V +
Sbjct 176 TSSQCNKKLIGAKYFINGFLATHESFNSTESLDFISPRDRSGHGTHVA-TIAGGSYVPSI 234
Query 209 GVCGV------GVAYNARIGGVRM---LD------GEVTDAVEARSLGLNPNHIHIYSAS 253
G+ G A ARI + LD D ++A ++ + + + S S
Sbjct 235 SYKGLAGGTVRGGAPRARIAMYKACWYLDRFDINTCSSADILKAMDEAMH-DGVDVLSLS 293
Query 254 WGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIY 313
G A + G V + GN G + + +
Sbjct 294 IGYR-----FPYFPETDVRAVIATGAFHAVLKGITVVCSGGNSGPAAQTVGN----TAPW 344
Query 314 TLSISSATQFGNVPWYSEACSSTLA---TTYSSGNQNEKQIVTTDLRQKCTESHTG 366
L++++ T + P ++ L Y+ +V + ES +G
Sbjct 345 ILTVAATTLDRSFPTPITLGNNKLILGQAMYTGPELGFTSLVYPENPGNSNESFSG 400
Score = 47.1 bits (110), Expect = 7e-04, Method: Composition-based stats.
Identities = 17/75 (23%), Positives = 34/75 (45%), Gaps = 2/75 (3%)
Query 364 HTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH- 422
+GTS +AP +G++AL +++ + ++ +V T+ G RK++
Sbjct 549 LSGTSMAAPTISGVVALLKALHRDWSPAAIRSAIVTTAWRTDPFGEQIFAEGSPRKLADP 608
Query 423 -SYGYGLLDAGAMVA 436
YG GL++
Sbjct 609 FDYGGGLVNPEKAAK 623
>sp|Q9FIG2|SBT4D_ARATH Subtilisin-like protease SBT4.13 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.13 PE=2 SV=1
Length=732
Score = 56.0 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 24/124 (19%), Positives = 40/124 (32%), Gaps = 16/124 (13%)
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
T+++ P + YS + + D R +GTS S P
Sbjct 473 NTIAVDILKPDITAP------GVEILAAYSPAGEPSQD----DTRHVKYSVLSGTSMSCP 522
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAG 432
AG+ A N + +Q ++ T+ P + A+ YG G +D
Sbjct 523 HVAGVAAYVKTFNPKWSPSMIQSAIMTTAWPVNATGTGIASTEFA------YGSGHVDPI 576
Query 433 AMVA 436
A
Sbjct 577 AASN 580
Score = 47.1 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 33/202 (16%), Positives = 69/202 (34%), Gaps = 38/202 (19%)
Query 147 IVVSILDDGIEKNHPDLAGNY------------DPGASFDVNDQ--DPDPQPRYTQMNDN 192
++ ++D GI + G +F N++ + +
Sbjct 135 TIIGVIDSGITPESQSFSDKGFGPPPQKWKGVCSGGKNFTCNNKLIGARDYTSEGTRDMD 194
Query 193 RHGTRCAGEVAAVA---------NNGVCGVGVAYNARIGGVRML--DGEVTDAVEARSLG 241
HGT A A A NG GV +R+ ++ G ++A+ +
Sbjct 195 GHGTHTASTAAGNAVVDASFFGIGNGTVRGGV-PASRVAAYKVCTPTGCSSEALLSAFDD 253
Query 242 LNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHD 301
+ + + + S G D ++ +A AF G + V ++GN G +
Sbjct 254 AIADGVDLITISIG--DKTASMFQNDPIAIGAFHAMA------KGVLTVNSAGNSGPKPI 305
Query 302 SCNCDGYTNSIYTLSISSATQF 323
S + + L+++++T
Sbjct 306 SV----SGVAPWILTVAASTTN 323
>sp|Q8L7I2|SBT36_ARATH Subtilisin-like protease SBT3.6 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.6 PE=2 SV=1
Length=778
Score = 56.0 bits (133), Expect = 1e-06, Method: Composition-based stats.
Identities = 49/359 (14%), Positives = 106/359 (30%), Gaps = 83/359 (23%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
Y + H + + ++ P V + + + W
Sbjct 74 YSYRHGFSGFAAKLTES-QAKKIADLPDVVHVIPDSFYKLAT------------TRTWDY 120
Query 125 SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG------------------N 166
G++ N K+ + G I++ ++D G+ N
Sbjct 121 LGLS--AANPKSLLHETNMGEQIIIGVIDTGVWPESEVFNDSGFGPVPSHWKGGCETGEN 178
Query 167 YDP--------GASFDVND--------QDPDPQPRYTQMNDNRHGTRCAGEVAA---VAN 207
++ GA + +N + + + + HGT + +A V N
Sbjct 179 FNSSNCNKKLIGAKYFINGFLAENESFNSTNSLDFISPRDLDGHGTHVS-TIAGGSFVPN 237
Query 208 NGVCGV------GVAYNARIGGVRM---LDGEVT------DAVEARSLGLNPNHIHIYSA 252
G+ G A A I + LD + T D ++A ++ + + + S
Sbjct 238 ISYKGLAGGTVRGGAPRAHIAMYKACWYLDDDDTTTCSSADILKAMDEAMH-DGVDVLSI 296
Query 253 SWGPEDDGKTVDGPARL-AEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNS 311
S G +V + G G V + GN G + + +
Sbjct 297 SLG-----SSVPLYGETDIRDGITTGAFHAVL-KGITVVCSGGNSGPDSLTVTN----TA 346
Query 312 IYTLSISSATQFGNVPWYSEACSSTLA---TTYSSGNQNEKQIVTTDLRQKCTESHTGT 367
+ +++++ T + ++ + Y+ +V + ES +GT
Sbjct 347 PWIITVAATTLDRSFATPLTLGNNKVILGQAMYTGPGLGFTSLVYPENPGNSNESFSGT 405
Score = 46.3 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 21/120 (18%), Positives = 43/120 (36%), Gaps = 8/120 (7%)
Query 325 NVPWYSEACSSTLA------TTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGII 378
V +S +++A + G T + +GTS +AP +G+
Sbjct 507 KVATFSSRGPNSIAPAILKPDIAAPGVSILAATTNTTFSDQGFIMLSGTSMAAPAISGVA 566
Query 379 ALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH--SYGYGLLDAGAMVA 436
AL +++ + ++ +V T+ G K++ YG GL++
Sbjct 567 ALLKALHRDWSPAAIRSAIVTTAWKTDPFGEQIFAEGSPPKLADPFDYGGGLVNPEKSAN 626
>sp|F4JXC5|SBT54_ARATH Subtilisin-like protease SBT5.4 OS=Arabidopsis
thaliana OX=3702 GN=SBT5.4 PE=1 SV=1
Length=778
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 41/312 (13%), Positives = 94/312 (30%), Gaps = 74/312 (24%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
++ + R + + + + + P V + ++ W
Sbjct 86 FYSYKRHINGFAAILDENEAAEIAKHPDVVSVFPNKGRK------------LHTTHSWNF 133
Query 125 SGVTQRDL-NVKAAWAQGYTGHGIVVSILDDGIEKN--------------------HPDL 163
+ + + + + W + G +++ LD G+ H D+
Sbjct 134 MLLAKNGVVHKSSLWNKAGYGEDTIIANLDTGVWPESKSFSDEGYGAVPARWKGRCHKDV 193
Query 164 AGNYDPGASFDVNDQD------PDPQPRYTQMNDNRHGTRCAGEVAAV---ANNGVCG-- 212
N + N P T + + HG+ A N
Sbjct 194 PCNRKLIGARYFNKGYLAYTGLPSNASYETCRDHDGHGSHTLSTAAGNFVPGANVFGIGN 253
Query 213 ---VGVAYNARIGGVRM----------LDGEVTDAVEARSLGLNPNHIHIYSASWGPEDD 259
G + AR+ ++ D ++ A+EA + + + SAS G +
Sbjct 254 GTASGGSPKARVAAYKVCWPPVDGAECFDADILAAIEAAI----EDGVDVLSASVGGDAG 309
Query 260 GKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISS 319
DG A + A GV+ V ++GN G + + + + + +++ +
Sbjct 310 DYMSDGIAIGSFHAVKNGVT---------VVCSAGNSGPKSGTVSN----VAPWVITVGA 356
Query 320 ATQFGNVPWYSE 331
++ + E
Sbjct 357 SSMDREFQAFVE 368
Score = 43.3 bits (100), Expect = 0.009, Method: Composition-based stats.
Identities = 16/105 (15%), Positives = 38/105 (36%), Gaps = 2/105 (2%)
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWR 391
A + ++ + +D R+ + +GTS S P +G++ L + + +
Sbjct 533 APGVNIIAAFTEATGPTD--LDSDNRRTPFNTESGTSMSCPHISGVVGLLKTLHPHWSPA 590
Query 392 DMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
++ ++ TS+ + + SYG G +
Sbjct 591 AIRSAIMTTSRTRNNRRKPMVDESFKKANPFSYGSGHVQPNKAAH 635
>sp|Q9MAP7|SBT35_ARATH Subtilisin-like protease SBT3.5 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.5 PE=1 SV=1
Length=774
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 45/314 (14%), Positives = 89/314 (28%), Gaps = 76/314 (24%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
Y + H + + +L P+V + Y+ T + W
Sbjct 69 YSYRHGFSGFAAKLTES-QAKKLADSPEVVHVMAD--------SFYELAT----TRTWDY 115
Query 125 SGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAGNYDP--------------- 169
G++ + N G +++ +D G+ N
Sbjct 116 LGLSVANPN--NLLNDTNMGDQVIIGFIDTGVWPESESFNDNGVGPIPSHWKGGCESGEK 173
Query 170 -----------GASFDVND--------QDPDPQPRYTQMNDNRHGTRCAGEVAA--VANN 208
GA + +N + + + + HGT A V N
Sbjct 174 FISTNCNRKLIGAKYFINGFLAENEGFNTTESRDYISARDFIGHGTHTASIAGGSFVPNI 233
Query 209 GVCGV------GVAYNARIGGVR---------MLDGEVTDAVEARSLGLNPNHIHIYSAS 253
G+ G A ARI + + +D ++A ++ + + + S S
Sbjct 234 SYKGLAGGNLRGGAPRARIAIYKACWYVDQLGAVACSSSDILKAMDESMH-DGVDVLSLS 292
Query 254 WGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIY 313
G + P + G G I V A GN G + + +
Sbjct 293 LG----AQIPLYPETDLRDRIATGAFHAV-AKGIIVVCAGGNSGPAAQTV----LNTAPW 343
Query 314 TLSISSATQFGNVP 327
+++++ T + P
Sbjct 344 IITVAATTLDRSFP 357
Score = 35.6 bits (80), Expect = 2.1, Method: Composition-based stats.
Identities = 23/121 (19%), Positives = 44/121 (36%), Gaps = 9/121 (7%)
Query 325 NVPWYSEACSSTLA---TTYSSGNQNEKQIVTTDLRQKCT----ESHTGTSASAPLAAGI 377
V +S ++++ G + T + + GTS +AP+ AG+
Sbjct 502 KVATFSSRGPNSISPAILKPDIGAPGVSILAATSPDSNSSVGGFDILAGTSMAAPVVAGV 561
Query 378 IALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH--SYGYGLLDAGAMV 435
+AL + N + + +V T+ G RKV+ YG G+++
Sbjct 562 VALLKALHPNWSPAAFRSAIVTTAWRTDPFGEQIFAEGSSRKVADPFDYGGGIVNPEKAA 621
Query 436 A 436
Sbjct 622 D 622
>sp|Q84WS0|SBT11_ARATH Subtilisin-like protease SBT1.1 OS=Arabidopsis
thaliana OX=3702 GN=SBTI1.1 PE=1 SV=1
Length=774
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 29/236 (12%), Positives = 63/236 (27%), Gaps = 57/236 (24%)
Query 136 AAWAQGYTGHGIVVSILDDGIEKNHPDLAG---------------------------NYD 168
W + +++ ++D GI H
Sbjct 135 GLWNETSLSSDVIIGLVDTGISPEHVSFRDTHMTPVPSRWRGSCDEGTNFSSSECNKKII 194
Query 169 PGASF-----DVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA---VANNGVC-----GVGV 215
++F + + + + + HGT A A N G+
Sbjct 195 GASAFYKGYESIVGKINETTDFRSTRDAQGHGTHTASTAAGDIVPKANYFGQAKGLASGM 254
Query 216 AYNARIGGVR---MLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEE 272
+ +RI + L TD + A + + + + S S G VD
Sbjct 255 RFTSRIAAYKACWALGCASTDVIAAIDRAI-LDGVDVISLSLGGSSRPFYVDP------- 306
Query 273 AFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPW 328
G ++GN G + + + + ++++++ P
Sbjct 307 --IAIAGFGAMQKNIFVSCSAGNSGPTASTVSN----GAPWLMTVAASYTDRTFPA 356
Score = 41.7 bits (96), Expect = 0.026, Method: Composition-based stats.
Identities = 11/56 (20%), Positives = 28/56 (50%), Gaps = 0/56 (0%)
Query 347 NEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSK 402
+ ++ +D R+ +GTS + P +GI AL + + + ++ ++ T++
Sbjct 531 SSPSLLRSDPRRVQFNIISGTSMACPHISGIAALIKSVHGDWSPAMIKSAIMTTAR 586
>sp|Q8T9W1|TAGD_DICDI Serine protease/ABC transporter B family
protein tagD OS=Dictyostelium discoideum OX=44689 GN=tagD PE=3
SV=1
Length=1825
Score = 55.6 bits (132), Expect = 2e-06, Method: Composition-based stats.
Identities = 53/320 (17%), Positives = 97/320 (30%), Gaps = 37/320 (12%)
Query 94 QWLEQQVAKRRTKRDVYQEPTDPK-----FPQQWYLSGVTQRDLNVKAAWAQGYTGHGIV 148
QW+ +Q +R + + F + L + D+ ++ G G +
Sbjct 282 QWISEQSESNYIERSEKFQTANRLSPKAIFGTKDTLVNNDRIDIPLR--------GKGQI 333
Query 149 VSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDN-----RHGTRCAGEVA 203
+SI D G++ +H + + +P VN ++DN HGT G A
Sbjct 334 LSIADTGLDGSHCFFSDSNNPIPYNSVNLNHRKVVTYIGSLHDNEDYVDGHGTHVCGSAA 393
Query 204 AVANNGVCGV----GVAYNARIGGVRMLDGEVT------DAVEARSLGLNPNHIHIYSAS 253
+ + G+A +A+I + + L ++ S
Sbjct 394 GAPEDSSLAISSFSGLATDAKIAFFDLASDPSNNEPVPPEDYSQLYQPLYNAGARVHGDS 453
Query 254 WGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIY 313
WG + + A + I + A+GN + + N I
Sbjct 454 WGSLSIQGYLGSYSDDAGSIDDFLYTHPDF----IILRAAGNNEQYSSLLSQATAKNVIT 509
Query 314 TLSISSATQFGNVPW--YSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHT--GTSA 369
+ + + YS + +T S + + T Q CTE T G S
Sbjct 510 VGAEQTTHESYTTDALEYSNFETVAKSTLNSLCQSFDDKYCTYTTAQCCTEYSTVKGLSG 569
Query 370 -SAPLAAGIIALTLEANKNL 388
A + L
Sbjct 570 CCTSYIKNSYASIFSSQPEL 589
>sp|Q9LNU1|CRSP_ARATH CO(2)-response secreted protease OS=Arabidopsis
thaliana OX=3702 GN=CRSP PE=2 SV=1
Length=769
Score = 55.2 bits (131), Expect = 2e-06, Method: Composition-based stats.
Identities = 38/210 (18%), Positives = 66/210 (31%), Gaps = 48/210 (23%)
Query 148 VVSILDDGIEKNHPDLAG--------------------------NYDPGASFDVNDQDPD 181
+V ILD GI GA + N D
Sbjct 140 IVGILDTGIWPESESFNDKDMGPIPSRWKGTCMEAKDFKSSNCNRKIIGARYYKNPDDDS 199
Query 182 PQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAY--------NARIGGVRML--DGEV 231
YT + HG+ + +A A GVA NARI ++ G
Sbjct 200 EY--YTTRDVIGHGSHVSSTIAGSAVENASYYGVASGTAKGGSQNARIAMYKVCNPGGCT 257
Query 232 TDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVW 291
++ A + + + S S G + +A AF V Q G + +
Sbjct 258 GSSILAAFDDAIADGVDVLSLSLGAPAYARIDLNTDPIAIGAF-HAVEQ-----GILVIC 311
Query 292 ASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
++GN G + + + + +++++ T
Sbjct 312 SAGNDGPDGGTVTN----TAPWIMTVAANT 337
Score = 53.7 bits (127), Expect = 6e-06, Method: Composition-based stats.
Identities = 35/233 (15%), Positives = 77/233 (33%), Gaps = 20/233 (9%)
Query 218 NARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRG 277
+A G R D + D + + + ++ + D+ K+ G + + R
Sbjct 382 DASEGSARACDSDSLDQEKVKGKIVLCENVGGSYYASSARDEVKSKGGTGCVFVDDRTRA 441
Query 278 VSQGRGGLGSIFV---WASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACS 334
V+ G + + A+ + + D + T ++ T V ++S
Sbjct 442 VASAYGSFPTTVIDSKEAA--EIFSYLNSTKDPVATILPTATVEKFTPAPAVAYFSSRGP 499
Query 335 STL-------------ATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALT 381
S+L + ++ N+ I +GTS +AP + + +L
Sbjct 500 SSLTRSILKPDITAPGVSILAAWTGNDSSISLEGKPASQYNVISGTSMAAPHVSAVASLI 559
Query 382 LEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH-SYGYGLLDAGA 433
+ ++ ++ T+ + N T G + G G L + A
Sbjct 560 KSQHPTWGPSAIRSAIMTTATQTN-NDKGLITTETGATATPYDSGAGELSSTA 611
>sp|Q9SVT4|SBT3E_ARATH Subtilisin-like protease SBT3.14 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.14 PE=3 SV=2
Length=759
Score = 54.8 bits (130), Expect = 2e-06, Method: Composition-based stats.
Identities = 42/232 (18%), Positives = 78/232 (34%), Gaps = 42/232 (18%)
Query 183 QPRYTQMNDNRHGTRCAGEVAA---VANNGVCGV------GVAYNARIGGVRM------L 227
Q + + HGT A +A V N G+ G A ARI ++
Sbjct 226 QDFKSNRDAIGHGTHTA-TIAGGSFVPNVSFYGLARGTVRGGAPRARIASYKVCWNVVGY 284
Query 228 DG--EVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGL 285
DG V D +A ++ + + + S S G P ++ +
Sbjct 285 DGICTVADMWKAFDDAIH-DQVDVLSVSIGA-------GIPENSEVDSVDFIAAFHAVAK 336
Query 286 GSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGN 345
G V A GN G + + + L++++ T + P ++ T ++
Sbjct 337 GITVVAAGGNDGPGAQNITNA----APWLLTVAATTLDRSFPTKITLGNNQ--TLFAESL 390
Query 346 QNEKQIVTT----------DLRQKCTESHTGTSASAPLAAGIIALTLEANKN 387
+I T+ D++ K T S+ G++A+ L +
Sbjct 391 FTGPEISTSLAFLDSDHNVDVKGKTILEFDSTHPSSIAGRGVVAVILAKKPD 442
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 20/75 (27%), Positives = 35/75 (47%), Gaps = 2/75 (3%)
Query 364 HTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH- 422
++GTS S P+ +GIIAL + N + M+ +V T+ + G +K++
Sbjct 538 YSGTSMSTPVVSGIIALLKSLHPNWSPAAMRSALVTTAWRTSPSGEPIFAQGSNKKLADP 597
Query 423 -SYGYGLLDAGAMVA 436
YG GL++
Sbjct 598 FDYGGGLVNPDKAAQ 612
>sp|Q9LUM3|SBT15_ARATH Subtilisin-like protease SBT1.5 OS=Arabidopsis
thaliana OX=3702 GN=SBT1.5 PE=2 SV=1
Length=775
Score = 54.4 bits (129), Expect = 3e-06, Method: Composition-based stats.
Identities = 38/272 (14%), Positives = 77/272 (28%), Gaps = 59/272 (22%)
Query 144 GHGIVVSILDDGIEKNHPDLAGNYDP----------GASFDV------------------ 175
G +V+ ++D G+ P AS D
Sbjct 128 GSDLVIGVIDTGVWPERPSFDDRGLGPVPIKWKGQCIASQDFPESACNRKLVGARFFCGG 187
Query 176 ----NDQDPDPQPRYTQMNDNRHGTRCAGEVAA--------VANNGVCGVGVAYNARIGG 223
N + + + + + HGT A A + G+A AR+
Sbjct 188 YEATNGKMNETTEFRSPRDSDGHGTHTASISAGRYVFPASTLGYAHGVAAGMAPKARLAA 247
Query 224 VRML---DGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQ 280
++ +D + A + + + + S S G +A G
Sbjct 248 YKVCWNSGCYDSDILAAFDTAVA-DGVDVISLSVGGVV--------VPYYLDAIAIGA-F 297
Query 281 GRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATT 340
G G ++GNGG + + + ++ + T + P + + + +
Sbjct 298 GAIDRGIFVSASAGNGGPGALTVTN----VAPWMTTVGAGTIDRDFPANVKLGNGKMISG 353
Query 341 YS--SGNQNEKQIVTTDLRQKCTESHTGTSAS 370
S G + + + G S+S
Sbjct 354 VSVYGGPGLDPGRMYPLVYGGSLLGGDGYSSS 385
Score = 51.7 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 18/90 (20%), Positives = 35/90 (39%), Gaps = 1/90 (1%)
Query 348 EKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLN 407
VT+D R+ +GTS + P +G+ AL A+ + + ++ ++ T+ +
Sbjct 529 GPSGVTSDNRRTEFNILSGTSMACPHVSGLAALLKAAHPDWSPAAIRSALITTAYTVDNS 588
Query 408 ANDWATNGVGRKVS-HSYGYGLLDAGAMVA 436
G S YG G + +
Sbjct 589 GEPMMDESTGNTSSVMDYGSGHVHPTKAMD 618
>sp|F4JJL8|SBT3F_ARATH Subtilisin-like protease SBT3.15 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.15 PE=2 SV=2
Length=761
Score = 54.4 bits (129), Expect = 4e-06, Method: Composition-based stats.
Identities = 57/387 (15%), Positives = 104/387 (27%), Gaps = 85/387 (22%)
Query 65 YHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYL 124
Y + H +L + ++ P+V + + + L
Sbjct 81 YSYQHGFSGFAALLTSS-QAKKISEHPEVIHVIPNRILKLKT---------TRIWDHLGL 130
Query 125 SGVTQRDLNVKAAWAQGYT-----GHGIVVSILDDGIEKNHPDLAGNYDP---------- 169
S + + +A A+G G ++ ++D GI
Sbjct 131 SPIPTSFSSSSSAKAKGLLHNTSMGSEAIIGVVDSGIWPESKVFNDQGLGPIPKRWRGKC 190
Query 170 -----------------GASFDVND---------QDPDPQPRYTQMNDNRHGTRCAGEVA 203
GA + + + + + HGT A +A
Sbjct 191 RSGEKFNATMHCNKKLIGAKYYQSGLLAMNGGKFNRIIIRDFKSNRDATGHGTHTA-TIA 249
Query 204 A---VANNGVCGV------GVAYNARIGGVRM---LDGEVTDAVEARSLGLNPNHIHIYS 251
V N G+ G A ARI + + G A + IH
Sbjct 250 GGSFVPNASFYGLARGTVRGGAPRARIASYKACWNVVGWGGICSSADMWKAYDDAIHDQV 309
Query 252 ASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDS-CNCDGYTN 310
+ R+ A F V G V A+GN G + CN
Sbjct 310 DVLSVSIGASIPEDSERVDFIAAFHAV-----AKGITVVAAAGNDGSGAQTICNVAP--- 361
Query 311 SIYTLSISSATQF----------GNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC 360
+ L++++ T N ++ + +L T D++ K
Sbjct 362 --WLLTVAATTLDRSFPTKITLGNNQTFFVSNLAESLFTGPEISTGLAFLDDDVDVKGKT 419
Query 361 TESHTGTSASAPLAAGIIALTLEANKN 387
T S+ G++A+ L +
Sbjct 420 ILEFDSTHPSSIAGRGVVAVILAKKPD 446
Score = 51.4 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 37/222 (17%), Positives = 67/222 (30%), Gaps = 41/222 (18%)
Query 364 HTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH- 422
H+GTS S P+ +GII L + + M+ +V T+ + G +K++
Sbjct 540 HSGTSMSTPVVSGIIVLLKSLHPKWSPAAMRSALVTTAWRTSPSGEPIFAQGSNKKLADP 599
Query 423 -SYGYGLLDAGAMV----------------------ALAQNWTTVAPQRKCIIDI----- 454
YG GL++ + + + KC I
Sbjct 600 FDYGGGLVNPEKAAKPGLVYDMGIKDYINYMCSAGYNDSSISRVLGKKTKCPIPKPSMLD 659
Query 455 LTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAIHLV-SPMGTRS 513
+ P LE T+T + I + A + L I L +P
Sbjct 660 INLPSITIPNLEKEVTLTRTVTNVGPIKSVYRAV----IESP----LGITLTVNPTILVF 711
Query 514 TLLAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTS 555
A R +S + + + W + + +
Sbjct 712 KSAAKRVLTFSVKAKTSHKVNSGYFFGSL---TWTDGVHDVT 750
>sp|P83543|TAMP_STRMB Transglutaminase-activating metalloprotease
OS=Streptomyces mobaraensis OX=35621 PE=1 SV=2
Length=760
Score = 54.1 bits (128), Expect = 5e-06, Method: Composition-based stats.
Identities = 70/389 (18%), Positives = 124/389 (32%), Gaps = 96/389 (25%)
Query 223 GVRMLDGEVTDAVEARSLGLNPNHIHIYSASW-------------GPED------DGKTV 263
+R +D D + I ++ +S GP+D D T
Sbjct 427 PLRYMDKPSKDGASKDAWYSGLGGIDVHYSSGPANHWFYLASEGSGPKDIGGVHYDSPTS 486
Query 264 DG----------PARLAEEAFFRGVSQGRGGLGS--IFVWASGNG-GREHDSCNCDGYTN 310
DG A++ +A + G+ +WA+G G D+ N N
Sbjct 487 DGLPVTGVGRDNAAKIWFKALTERMQSNTDYKGARDATLWAAGELFGVNSDTYNN--VAN 544
Query 311 SIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTG--TS 368
+ +++ G + S G+Q L+ K T S +G T
Sbjct 545 AWAAINVGPRASSG-------------VSVTSPGDQTSIVNQAVSLQIKATGSTSGALTY 591
Query 369 ASAPLAAGII-----ALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATN--GVGRKVS 421
++ L AG+ L ++ V ++ + W N G G
Sbjct 592 SATGLPAGLSINASTGLISGTPTTTGTSNVTVTVKDSAGKTGSTSFKWTVNTTGGGSVFE 651
Query 422 HSYGYGLLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHI 481
++ + DAGA V VT P+ +
Sbjct 652 NTTQVAIPDAGAAVT------------------------------SPIVVTRSGNGPSAL 681
Query 482 TRLEHAQARLTLSYNRRGDLAIHLVSPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWDE 541
+ +++ RGDL I LV+P G L + D +AD + T +
Sbjct 682 K------VDVNITHTYRGDLTIDLVAPNGKTWRLKNSDAWDSAADVSETY---TVDASSV 732
Query 542 DPSGEWVLEIENTSEANNYGTLTKFTLVL 570
+G W L++++ ++ GT+ K+ L
Sbjct 733 SANGTWKLKVQDVYSGDS-GTIDKWRLTF 760
>sp|Q9FIM5|SBT49_ARATH Subtilisin-like protease SBT4.9 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.9 PE=2 SV=1
Length=713
Score = 53.7 bits (127), Expect = 6e-06, Method: Composition-based stats.
Identities = 25/127 (20%), Positives = 43/127 (34%), Gaps = 20/127 (16%)
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
T+++ P + +S N + D R +GTS S P
Sbjct 452 NTIAVDILKPDVTAP------GVEILAAFSPLNSPAQD--KRDNRHVKYSVLSGTSMSCP 503
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHS---YGYGLL 429
AG+ A + + +Q ++ T+ W N G V+ + YG G +
Sbjct 504 HVAGVAAYIKTFHPEWSPSMIQSAIMTTA---------WPMNATGTAVASTEFAYGAGHV 554
Query 430 DAGAMVA 436
D A +
Sbjct 555 DPIAAIN 561
Score = 51.0 bits (120), Expect = 4e-05, Method: Composition-based stats.
Identities = 56/296 (19%), Positives = 92/296 (31%), Gaps = 53/296 (18%)
Query 147 IVVSILDDGIEKNHPDLAGNY------------DPGASFDVNDQ--DPDPQPRYTQMNDN 192
++ +D GI + G +F N++ +
Sbjct 139 TIIGFIDSGIWPESESFSDKGFGPPPKKWKGVCSAGKNFTCNNKLIGARDYTNEGTRDIE 198
Query 193 RHGTRCAGEVA--AVANNGVCGV------GVAYNARIGGVRMLD--GEVTDAVEARSLGL 242
HGT A A AV N G+ G +RI + G T++V +
Sbjct 199 GHGTHTASTAAGNAVKNTSFYGIGNGTARGGVPASRIAAYKACSEMGCTTESVLSAFDDA 258
Query 243 NPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDS 302
+ + + S S G P +A AF V G + V ++GNGG
Sbjct 259 IADGVDLISISLGANLVRTYETDP--IAIGAFHAMV------KGILTVQSAGNGG----- 305
Query 303 CNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTE 362
G S+ ++ A N + T + K + DL+ K
Sbjct 306 -PNPGSVMSVAPWILTVAASNTNRGF------VTKVVLGNGKTFVGKSLNAFDLKGKNYP 358
Query 363 SHTGTSASAPLAAGIIAL--------TLEANKNLTWRDMQHLVVQTSKPAHLNAND 410
+ G S PL G I + + AN N + D ++ + S + D
Sbjct 359 LYGG-STDGPLLRGKILVSEDKVSSEIVVANINENYHDYAYVSILPSSALSKDDFD 413
>sp|Q9FGU3|SBT44_ARATH Subtilisin-like protease SBT4.4 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.4 PE=2 SV=1
Length=741
Score = 53.7 bits (127), Expect = 6e-06, Method: Composition-based stats.
Identities = 19/105 (18%), Positives = 39/105 (37%), Gaps = 8/105 (8%)
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWR 391
A + YS + + D R+ +GTS + P AG+ A + +
Sbjct 494 APGVEILAAYSPDSSPTESEF--DTRRVKYSVLSGTSMACPHVAGVAAYVKTFHPQWSPS 551
Query 392 DMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
+Q ++ T+ P + + + + + YG G +D +
Sbjct 552 MIQSAIMTTAWPMNASGSGFVSTEFA------YGSGHVDPIDAIN 590
Score = 52.5 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 47/254 (19%), Positives = 77/254 (30%), Gaps = 51/254 (20%)
Query 147 IVVSILDDGIEKNHPDL------------AGNYDPGASFDVN-------DQDPDPQPRYT 187
++ ++D GI G G +F N D + T
Sbjct 138 TIIGVIDSGIYPESDSFSDQGFGPPPKKWKGTCAGGKNFTCNNKVIGARDYTAKSKANQT 197
Query 188 QMNDNRHGTRCAGEVA--AVANNGVCGV------GVAYNARIGGVRMLDGEVTDAVEARS 239
+ + HGT A A AVAN+ G+ G ARI ++ D E D EA
Sbjct 198 ARDYSGHGTHTASIAAGNAVANSNFYGLGNGTARGGVPAARIAVYKVCDNEGCDG-EAMM 256
Query 240 LGLN---PNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
+ + + + S S +D E+ G +G + V A+GN
Sbjct 257 SAFDDAIADGVDVISISI-------VLDNIPPFEEDPIAIGAFHAM-AVGVLTVNAAGNN 308
Query 297 GREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDL 356
G I T++ ++ F + + + T D+
Sbjct 309 GP------------KISTVTSTAPWVFSVAASVTNRAFMAKVVLGDGKILIGRSVNTYDM 356
Query 357 RQKCTESHTGTSAS 370
G SA+
Sbjct 357 NGTNYPLVYGKSAA 370
>sp|Q8L7D2|SBT4C_ARATH Subtilisin-like protease SBT4.12 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.12 PE=2 SV=1
Length=736
Score = 53.3 bits (126), Expect = 8e-06, Method: Composition-based stats.
Identities = 24/124 (19%), Positives = 41/124 (33%), Gaps = 16/124 (13%)
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
T+++ P LA +G +E D R+ +GTS + P
Sbjct 474 NTIAVDILKPDITAP-----GVEILAAFSPNGEPSED-----DTRRVKYSVFSGTSMACP 523
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAG 432
AG+ A + +Q ++ T+ P A+ YG G +D
Sbjct 524 HVAGVAAYVKTFYPRWSPSMIQSAIMTTAWPVKAKGRGIASTEFA------YGAGHVDPM 577
Query 433 AMVA 436
A +
Sbjct 578 AALN 581
Score = 47.1 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 35/249 (14%), Positives = 80/249 (32%), Gaps = 44/249 (18%)
Query 147 IVVSILDDGIEKNHPDLAGNY------------DPGASFDVNDQ--DPDPQPRYTQMNDN 192
++ ++D GI + G +F N++ + +
Sbjct 136 TIIGVIDTGIWPESKSFSDKGFGPPPKKWKGVCSGGKNFTCNNKLIGARDYTSEGTRDTS 195
Query 193 RHGTRCAGEVA--AVANNGVCGV------GVAYNARIGGVRML--DGEVTDAVEARSLGL 242
HGT A A AV + G+ G +RI ++ G ++A+ +
Sbjct 196 GHGTHTASTAAGNAVKDTSFFGIGNGTVRGGVPASRIAAYKVCTDSGCSSEALLSSFDDA 255
Query 243 NPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDS 302
+ + + + S G P+ ++ G G + V ++GN G +
Sbjct 256 IADGVDLITISIG-------FQFPSIFEDDPIAIGAFHAM-AKGILTVSSAGNSGPK--- 304
Query 303 CNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTE 362
+ + +++++T + T + + + D++ K
Sbjct 305 -PTTVSHVAPWIFTVAAST--------TNRGFITKVVLGNGKTLAGRSVNAFDMKGKKYP 355
Query 363 SHTGTSASA 371
G SA++
Sbjct 356 LVYGKSAAS 364
>sp|Q9FIF8|SBT43_ARATH Subtilisin-like protease SBT4.3 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.3 PE=3 SV=1
Length=729
Score = 53.3 bits (126), Expect = 9e-06, Method: Composition-based stats.
Identities = 18/104 (17%), Positives = 35/104 (34%), Gaps = 8/104 (8%)
Query 331 EACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTW 390
A + +S + D R +GTS + P AG+ A + + +
Sbjct 484 SAPGLEILAAFSPVASPSSFLNPEDKRSVRYSVMSGTSMACPHVAGVAAYVKSFHPDWSP 543
Query 391 RDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAM 434
++ ++ T+ P +L N YG G ++
Sbjct 544 SAIKSAIMTTATPMNLKKNPEQEFA--------YGSGQINPTKA 579
Score = 49.0 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 33/214 (15%), Positives = 69/214 (32%), Gaps = 37/214 (17%)
Query 135 KAAWAQGYTGHGIVVSILDDGIEKNHPDL------------AGNYDPGASFDVNDQ---- 178
+ A + ++V ++D GI G+ G F N++
Sbjct 121 EKARRESVKESDVIVGVIDSGIWPESESFDDEGFGPPPKKWKGSCKGGLKFACNNKLIGA 180
Query 179 DPDPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVA--------YNARIGGVRMLDGE 230
+ + ++ HGT A A A G+A +ARI ++
Sbjct 181 RFYNKFADSARDEEGHGTHTASTAAGNAVQAASFYGLAQGTARGGVPSARIAAYKVCFNR 240
Query 231 VTD-AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIF 289
D + A + + + S S + ++ + F + +G GS
Sbjct 241 CNDVDILAAFDDAIADGVDVISISISADYVSNLLNASVAIGS---FHAMMRGIITAGS-- 295
Query 290 VWASGNGGREHDSCNCDGYTNSIYTLSISSATQF 323
+GN G + S S + ++++++
Sbjct 296 ---AGNNGPDQGSVAN----VSPWMITVAASGTD 322
>sp|P0CY46|EGFR_APIME Epidermal growth factor receptor OS=Apis
mellifera OX=7460 GN=Egfr PE=2 SV=1
Length=1292
Score = 52.9 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 35/167 (21%), Positives = 54/167 (32%), Gaps = 19/167 (11%)
Query 576 EGLPVPPESSG--CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDV 633
E P+ P +S C+ S C C G+ H+ C Q C + D
Sbjct 504 EQGPLKPLASKAVCRKCHS--RCKKC-TGYGFHEHVC-QECTK--YKRGEQCEDECPADY 557
Query 634 ETIRASVCAPCHASCATCQGPALTDCLSCP-SHASLDP----------VEQTCSRQSQSS 682
+C PC + C C GP C C +D +TC+ +
Sbjct 558 FADANKLCIPCFSECRGCFGPGPNQCYKCRNYKIYIDEDTDGNTTSFNCTETCTPEYPHK 617
Query 683 RESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVF 729
+P + L L+ +L +A L A I++ F
Sbjct 618 IFNPDSEPYCSLETAGLIENELQPAILAGVAVFALAFLVVAAIIMYF 664
>sp|F4HSQ2|SBT51_ARATH Subtilisin-like protease SBT5.1 OS=Arabidopsis
thaliana OX=3702 GN=SBT5.1 PE=3 SV=1
Length=780
Score = 52.5 bits (124), Expect = 1e-05, Method: Composition-based stats.
Identities = 33/163 (20%), Positives = 59/163 (36%), Gaps = 26/163 (16%)
Query 170 GASFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA--VANNGVCGV------GVAYNARI 221
GA + + DP T + HGT A A +AN G+ G + ++RI
Sbjct 192 GARYYNSSFFLDP-DYETPRDFLGHGTHVASIAAGQIIANASYYGLASGIMRGGSPSSRI 250
Query 222 GGVR---MLDGEVTDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGV 278
R +L + + A + + + + S S G P L E+ G
Sbjct 251 AMYRACSLLGCRGSSILAAFDDAIA-DGVDVISISMGLW--------PDNLLEDPLSIGS 301
Query 279 SQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSAT 321
G V + GN G S + + + ++++++T
Sbjct 302 FHAVER-GITVVCSVGNSGPSSQSV----FNAAPWMITVAAST 339
Score = 44.8 bits (104), Expect = 0.004, Method: Composition-based stats.
Identities = 14/66 (21%), Positives = 27/66 (41%), Gaps = 2/66 (3%)
Query 365 TGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH-S 423
+GTS S P +GI A + + ++ ++ T+ + T G K +
Sbjct 547 SGTSMSCPHVSGIAARLKSRYPSWSPAAIRSAIMTTAVQMTNTGSH-ITTETGEKATPYD 605
Query 424 YGYGLL 429
+G G +
Sbjct 606 FGAGQV 611
>sp|Q9STF7|SBT46_ARATH Subtilisin-like protease SBT4.6 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.6 PE=3 SV=1
Length=736
Score = 52.5 bits (124), Expect = 2e-05, Method: Composition-based stats.
Identities = 23/105 (22%), Positives = 40/105 (38%), Gaps = 9/105 (9%)
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWR 391
A S + YS + +D R +GTS S P AG+ A + +
Sbjct 495 APGSEILAAYSPYVPPSE----SDTRHVKYTVISGTSMSCPHVAGVAAYIKTFHPLWSPS 550
Query 392 DMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVA 436
+Q ++ T+ P + + T+ +YG G +D A +
Sbjct 551 MIQSAIMTTAWPMNAS-----TSPSNELAEFAYGAGHVDPIAAIH 590
Score = 50.6 bits (119), Expect = 5e-05, Method: Composition-based stats.
Identities = 48/258 (19%), Positives = 83/258 (32%), Gaps = 54/258 (21%)
Query 147 IVVSILDDGIEKNHPDLAGNY------------DPGASFDVNDQ-------DPDPQPRYT 187
++ ++D GI +G G +F N++ P +
Sbjct 137 TIIGVIDSGIYPESDSFSGKGFGPPPKKWKGVCKGGTNFTCNNKLIGARYYTPKLEGFPE 196
Query 188 QMNDN-RHGTRCAGEVAAVA---------NNGVCGVGVAYNARIGGVRMLDGEV----TD 233
DN HG+ A A A NG GV ARI ++ D V +D
Sbjct 197 SARDNTGHGSHTASIAAGNAVKHVSFYGLGNGTVRGGV-PAARIAVYKVCDPGVIRCTSD 255
Query 234 AVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWAS 293
+ A + + I + S G D T + E+ G G + V +
Sbjct 256 GILAAFDDAIADKVDIITVSLGA-DAVGTFE------EDTLAIGAFHAM-AKGILTVNGA 307
Query 294 GNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVT 353
GN G E + + + + ++++ N + T + + + +
Sbjct 308 GNNGPERRTI----VSMAPWLFTVAA--SNMNRAF------ITKVVLGNGKTIVGRSVNS 355
Query 354 TDLRQKCTESHTGTSASA 371
DL K G SAS+
Sbjct 356 FDLNGKKYPLVYGKSASS 373
>sp|P54683|TAGB_DICDI Serine protease/ABC transporter B family
protein tagB OS=Dictyostelium discoideum OX=44689 GN=tagB PE=3
SV=2
Length=1906
Score = 52.1 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 41/242 (17%), Positives = 77/242 (32%), Gaps = 33/242 (14%)
Query 94 QWLEQQVAKRRTKRD-----VYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTGHGIV 148
+W+ +Q +R + F + L + D+ ++ G G +
Sbjct 331 KWISEQSESNYIERSEKLQTANRLSPTVIFGTKDKLVNNDRIDIPLR--------GKGQI 382
Query 149 VSILDDGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMND----NRHGTRCAGEVAA 204
+SI D G++ +H + + P VN+ T ++ N HGT G A
Sbjct 383 LSIADTGLDGSHCFFSDSKYPIPFNQVNENHRKVVTYITYHDNEDYVNGHGTHVCGSAAG 442
Query 205 VANNGVCGV----GVAYNARIGGVRMLDGEVT----DAVEARSLGLNPNHIHIYSASWGP 256
+ + G+A +A+I + G + L ++ SWG
Sbjct 443 TPEDSSWAISSFSGLATDAKIAFYDLSSGSSEPTPPEDYSQMYKPLYDAGARVHGDSWGS 502
Query 257 EDDGKTVDGPARLA--EEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYT 314
G + A +AF + + A+GN N+I
Sbjct 503 VSLQGYYGGYSDDAGGIDAFLYEYPEFS------ILRAAGNNELFASLLAQATAKNAITV 556
Query 315 LS 316
+
Sbjct 557 GA 558
>sp|Q9FIM6|SBT48_ARATH Subtilisin-like protease SBT4.8 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.8 PE=3 SV=1
Length=710
Score = 51.4 bits (121), Expect = 3e-05, Method: Composition-based stats.
Identities = 22/127 (17%), Positives = 42/127 (33%), Gaps = 20/127 (16%)
Query 313 YTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAP 372
T+++ A + YS + + D R+ +GTS + P
Sbjct 451 NTIAVDILKPD------ISAPGVEILAAYSPLSLPSED--RRDKRRVKYSVLSGTSMACP 502
Query 373 LAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHS---YGYGLL 429
G+ A + + + +Q ++ T+ W N G + YG G +
Sbjct 503 HVTGVAAYIKTFHPDWSPSVIQSAIMTTA---------WQMNATGTGAESTEFAYGAGHV 553
Query 430 DAGAMVA 436
D A +
Sbjct 554 DPIAAIN 560
Score = 51.0 bits (120), Expect = 4e-05, Method: Composition-based stats.
Identities = 33/201 (16%), Positives = 65/201 (32%), Gaps = 36/201 (18%)
Query 147 IVVSILDDGIEKNHPDLAGNY------------DPGASFDVNDQ--DPDPQPRYTQMNDN 192
++ +D GI + G +F N++ +
Sbjct 137 TIIGFIDSGIWPESESFSDKGFGPPPKKWKGVCKGGKNFTCNNKLIGARDYTSEGTRDLQ 196
Query 193 RHGTRCAGEVA--AVANNGVCGV------GVAYNARIGGVRM--LDGEVTDAVEARSLGL 242
HGT A AVA+ G+ G +R+ ++ + G D V +
Sbjct 197 GHGTHTTSTAAGNAVADTSFFGIGNGTARGGVPASRVAAYKVCTITGCSDDNVLSAFDDA 256
Query 243 NPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDS 302
+ + + S S G + P+ AE+ G G + V ++GN G
Sbjct 257 IADGVDLISVSLGGDY-------PSLYAEDTIAIGAFHAM-AKGILTVHSAGNAGPN--- 305
Query 303 CNCDGYTNSIYTLSISSATQF 323
+ + + L++++ T
Sbjct 306 -PTTVVSVAPWMLTVAATTTN 325
>sp|Q03185|TS11_GIAIN Major surface trophozoite antigen 11 OS=Giardia
intestinalis OX=5741 GN=TSP11 PE=3 SV=1
Length=667
Score = 50.6 bits (119), Expect = 6e-05, Method: Composition-based stats.
Identities = 31/139 (22%), Positives = 46/139 (33%), Gaps = 31/139 (22%)
Query 578 LPVPPESSGCKTLTSS----QACVVCEEGFSLHQKS-CVQHC-------PPGFAPQVLDT 625
+ ++ CK T+ + C C L S CVQ+C A
Sbjct 280 VKSDCKTENCKACTNPKAANEVCTECISTHHLTPTSQCVQYCQALGNYYAGTNADNKKAC 339
Query 626 HYSTENDVET---------------IRASVCAPCHASCATCQGPALTDCLSCPSHASL-- 668
T + +T C+PCH SC TC +DC CP+ +L
Sbjct 340 KECTVANCKTCNDQGQCQTCNDGFYKNGDACSPCHESCKTCSAGTASDCTECPTGKALKY 399
Query 669 --DPVEQTCSRQSQSSRES 685
D + TC + + S
Sbjct 400 GNDGTKGTCGEGCTTGQGS 418
Score = 41.3 bits (95), Expect = 0.034, Method: Composition-based stats.
Identities = 20/117 (17%), Positives = 36/117 (31%), Gaps = 6/117 (5%)
Query 568 LVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKS---CVQHCPPGFAPQVLD 624
L + G E P +S + C G+ + C + C
Sbjct 478 LRMNGGCYETTKFPGKSVCEGANADADTCKAPVPGYKVEAGKLVMCSKGCD--TCSDATT 535
Query 625 THYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
+ + + C C +SC TC G A T C C + + ++ ++
Sbjct 536 CTKCGDGYTKIENSQTCTKCDSSCETCTG-AATTCKVCATGYYKTALGESTCTSCEN 591
Score = 34.8 bits (78), Expect = 3.5, Method: Composition-based stats.
Identities = 22/111 (20%), Positives = 34/111 (31%), Gaps = 9/111 (8%)
Query 589 TLTSSQACVVCEEGFSLHQ-----KSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
T S + C C G S C++ + L + ++ + C
Sbjct 190 TAESKKTCKSCTGGSSEAPNVKGIGDCLKCMYNEASGNTLTCEKCSAQKKPSLDKTSCND 249
Query 644 CH-ASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPR 693
C +CA C + DC C S LD Q C + + P
Sbjct 250 CTGQNCAFC-SSSGGDCEGCDSGFILDG--QNCVKSDCKTENCKACTNPKA 297
>sp|Q23868|TAGC_DICDI Serine protease/ABC transporter B family
protein tagC OS=Dictyostelium discoideum OX=44689 GN=tagC PE=2
SV=2
Length=1741
Score = 50.6 bits (119), Expect = 7e-05, Method: Composition-based stats.
Identities = 41/232 (18%), Positives = 80/232 (34%), Gaps = 32/232 (14%)
Query 85 SRLQREPQV-QWLEQQVAKRRTKRDVYQEPTDPK-----FPQQWYLSGVTQRDLNVKAAW 138
S + E V QW+ +Q +R + + F + L + D+ ++
Sbjct 259 SLINSEKLVYQWISEQSESNFIERSEKFQTANRLSPKVVFGTKDTLVNNDRVDIPLR--- 315
Query 139 AQGYTGHGIVVSILDDGIEKNHPDLAGNY--DPGASFDVNDQDPDPQPRYTQMND----N 192
G G ++SI D G++ +H + + P S ++N + + +D +
Sbjct 316 -----GKGQILSIADTGLDGSHCFFSDSKYPIPLNSVNLNHRKVVTYITTSTSDDSDKVD 370
Query 193 RHGTRCAGEVAAVANNGVCGV----GVAYNARIGGVRMLDGEVT----DAVEARSLGLNP 244
HGT G A + + G+A +A+I + G + ++ L
Sbjct 371 GHGTHICGSAAGTPEDSSVNISSFSGLATDAKIAFFDLASGSSSLTPPSDLKQLYQPLYD 430
Query 245 NHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
++ SWG +V+G I + A+GN
Sbjct 431 AGARVHCDSWG----SVSVEGYTGSYSSDTASIDDFLFTHPDFIILRAAGNN 478
>sp|Q9STQ2|SBT3I_ARATH Subtilisin-like protease SBT3.18 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.18 PE=3 SV=2
Length=779
Score = 49.8 bits (117), Expect = 9e-05, Method: Composition-based stats.
Identities = 21/113 (19%), Positives = 46/113 (41%), Gaps = 4/113 (4%)
Query 365 TGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSY 424
+GTS S P AG++AL A+ + + ++ ++ T+ + D +G K + +
Sbjct 550 SGTSMSCPHVAGVMALLQSAHPDWSPSAIRSAIMTTA-YTRDTSYDLILSGGSMKSTDPF 608
Query 425 --GYGLLDAGAMVALAQNWTT-VAPQRKCIIDILTEPKDIGKRLEVRKTVTAC 474
G G ++ + + T + +I ++I + + T C
Sbjct 609 DIGAGHINPLKAMDPGLVYNTRTDDYVLFMCNIGYTDQEIKSMVLHPEPSTTC 661
Score = 49.0 bits (115), Expect = 2e-04, Method: Composition-based stats.
Identities = 46/237 (19%), Positives = 73/237 (31%), Gaps = 66/237 (28%)
Query 144 GHGIVVSILDDGIEKNHPDLA-------------GNYDPGASFDVNDQ------------ 178
G IVV I D GI G G FD +
Sbjct 135 GSDIVVGIFDTGIWPESESFRETPEAKPIPSSWNGKCVGGEDFDPSVHCNRKLIGARFYL 194
Query 179 ----------DPDPQPRY-TQMNDNRHGTRCAGE-VAAVANNGVCGVGV--------AYN 218
D P Y + + HGT A V +V N G+ A
Sbjct 195 RGFEETYGTIDFTRDPEYRSPRDYLGHGTHTASTAVGSVVRNVSGFFGLGRGTARGGAPL 254
Query 219 ARIGGVRM-----LDGEVT--DAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAE 271
AR+ + L+G T D + A ++ + +H+ SAS+G + E
Sbjct 255 ARLAVFKTCWGKDLEGVCTEADILAAFDDAIH-DGVHVISASFGYS------PPLSPFFE 307
Query 272 EAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPW 328
+ G G V+++GN G + G ++ ++S A + +
Sbjct 308 SSADIGAFHAAER-GISVVFSTGNDGPD------PGVVQNVAPWAVSVAASTVDRSF 357
>sp|Q1PDX5|SBT3B_ARATH Subtilisin-like protease SBT3.11 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.11 PE=2 SV=1
Length=762
Score = 49.8 bits (117), Expect = 9e-05, Method: Composition-based stats.
Identities = 16/74 (22%), Positives = 35/74 (47%), Gaps = 2/74 (3%)
Query 365 TGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH-- 422
+GTS S P+ AG++AL + + + ++ ++ T+ + G+ RK++
Sbjct 537 SGTSMSTPVVAGLVALLRAVHPDWSPAALKSALITTASTTDPYGEPIFSEGMTRKLADPF 596
Query 423 SYGYGLLDAGAMVA 436
+G GL++
Sbjct 597 DFGGGLVNPNKAAD 610
Score = 44.4 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 39/230 (17%), Positives = 65/230 (28%), Gaps = 65/230 (28%)
Query 144 GHGIVVSILDDGIEKNHPDLAGNYDP------------GASFD----------------- 174
G I++ +LD G+ G FD
Sbjct 141 GEDIIIGVLDSGVWPESQSFNDKGLGPIPKRWKGMCVDGEDFDSKKHCNKKLIGARYYMD 200
Query 175 --VNDQDPD---PQPRYTQMNDN-RHGTRCAGEVAA-----VANNGVCG---VGVAYNAR 220
D P Y ++ HGT A V++NG G A AR
Sbjct 201 SLFRRNKTDSGIPDTEYMSARESLPHGTHVASTAGGSFVSNVSDNGFGVGTIRGGAPRAR 260
Query 221 IGGVRMLDGEV------TDAVEARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAF 274
I ++ V D ++A + + + + + S G + T
Sbjct 261 IAVYKVCWQRVDRTCASADIIKAMDDAIA-DGVDLITISIGRPNPVLTEVDVYNQISYGA 319
Query 275 FRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTN---SIYTLSISSAT 321
F V G + A GN G YT + + +++++ T
Sbjct 320 FHAV-----AKGIPVLSAGGNFGPG-------AYTVQNIAPWIITVAATT 357
>sp|Q5R328|RSPO3_DANRE R-spondin-3 OS=Danio rerio OX=7955 GN=rspo3
PE=2 SV=2
Length=317
Score = 48.3 bits (113), Expect = 1e-04, Method: Composition-based stats.
Identities = 27/117 (23%), Positives = 37/117 (32%), Gaps = 20/117 (17%)
Query 570 LYGT-APEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYS 628
YGT +P+ S C + + C+ C G LH+ C++ CP G
Sbjct 84 FYGTRSPDRNDCIKCGSECDSCFNRNFCLRCRAGSYLHKGKCMESCPDGL---------- 133
Query 629 TENDVETIRASVCA-PCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRE 684
V + C C A C CQ C C L + C E
Sbjct 134 ----VPSDTKKECVAACPALCDLCQNS--DTCTRCVPGHFLHAGQ--CHHVCPDEFE 182
Score = 39.4 bits (90), Expect = 0.11, Method: Composition-based stats.
Identities = 21/109 (19%), Positives = 33/109 (30%), Gaps = 15/109 (14%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKS--------CVQHCPPGFA----PQVLDTHYSTEN 631
GC+T + C+ C+ +H + C+ CP GF P D
Sbjct 42 QGGCQTCSVYNGCLTCKPKLFIHLERDGMRQIGVCLASCPNGFYGTRSPDRNDCIKCGSE 101
Query 632 DVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQ 680
+ C C A +G + SCP ++ C
Sbjct 102 CDSCFNRNFCLRCRAGSYLHKGKCME---SCPDGLVPSDTKKECVAACP 147
>sp|Q9FIG1|SBT4B_ARATH Subtilisin-like protease SBT4.11 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.11 PE=2 SV=2
Length=736
Score = 48.7 bits (114), Expect = 2e-04, Method: Composition-based stats.
Identities = 38/200 (19%), Positives = 67/200 (34%), Gaps = 35/200 (18%)
Query 147 IVVSILDDGIEKNHPDLAGNY------------DPGASFDVNDQ--DPDPQPRYTQMNDN 192
++ + D GI + G +F N++ +
Sbjct 139 TIIGVFDGGIWPESESFSDKGFGPPPKKWKGICAGGKNFTCNNKLIGARHYSPGDARDST 198
Query 193 RHGTRCAGEVA--AVANNGVCGV------GVAYNARIGGVRMLDGEVT-DAVEARSLGLN 243
HGT A A AVAN G+ G +RI R+ GE DA+ +
Sbjct 199 GHGTHTASIAAGNAVANTSFFGIGNGTVRGAVPASRIAVYRVCAGECRDDAILSAFDDAI 258
Query 244 PNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSC 303
+ + I + S G D E+ + G + V A+GN G + S
Sbjct 259 SDGVDIITISIG--------DINVYPFEKDPIAIGAFHAMSKGILTVNAAGNTGPDTASI 310
Query 304 NCDGYTNSIYTLSISSATQF 323
+ + + L+++++T
Sbjct 311 T----SLAPWLLTVAASTAN 326
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 16/76 (21%), Positives = 31/76 (41%), Gaps = 6/76 (8%)
Query 361 TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKV 420
+GTS S P AAG+ A + + ++ ++ T+ + + + +A+
Sbjct 511 YSVESGTSMSCPHAAGVAAYVKTFHPQWSPSMIKSAIMTTAWSMNASQSGYASTEFA--- 567
Query 421 SHSYGYGLLDAGAMVA 436
YG G +D A
Sbjct 568 ---YGAGHVDPIAATN 580
>sp|Q9SZV5|SBT26_ARATH Subtilisin-like protease SBT2.6 OS=Arabidopsis
thaliana OX=3702 GN=SBT2.6 PE=2 SV=1
Length=816
Score = 48.3 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 23/113 (20%), Positives = 44/113 (39%), Gaps = 13/113 (12%)
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWR 391
A S + + +S+ +E + + +GTS +AP AGI AL + + +
Sbjct 566 APGSLIWSAWSANGTDEANYI-----GEGFALISGTSMAAPHIAGIAALVKQKHPQWSPA 620
Query 392 DMQHLVVQTSKPAH-----LNANDWATNGVGRKVSH---SYGYGLLDAGAMVA 436
++ ++ TS L A ++ V YG G ++ A +
Sbjct 621 AIKSALMTTSTVIDRAGRPLQAQQYSETETVTLVKATPFDYGSGHVNPSAALD 673
>sp|O65351|SBT17_ARATH Subtilisin-like protease SBT1.7 OS=Arabidopsis
thaliana OX=3702 GN=SBT1.7 PE=1 SV=1
Length=757
Score = 48.3 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 29/152 (19%), Positives = 54/152 (36%), Gaps = 23/152 (15%)
Query 187 TQMNDNRHGTRCAGEVAAVANNGVCGV--------GVAYNARIGGVRM--LDGEVTDAVE 236
+ +D+ HGT + A G + G+A AR+ ++ L G + +
Sbjct 205 SPRDDDGHGTHTSSTAAGSVVEGASLLGYASGTARGMAPRARVAVYKVCWLGGCFSSDIL 264
Query 237 ARSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNG 296
A +++++ S S G DG A A A R G + ++GN
Sbjct 265 AAIDKAIADNVNVLSMSLGGGMSDYYRDGVAIGAFAAMER---------GILVSCSAGNA 315
Query 297 GREHDSCNCDGYTNSIYTLSISSATQFGNVPW 328
G S + + ++ + T + P
Sbjct 316 GPSSSS----LSNVAPWITTVGAGTLDRDFPA 343
Score = 47.9 bits (112), Expect = 4e-04, Method: Composition-based stats.
Identities = 35/242 (14%), Positives = 71/242 (29%), Gaps = 22/242 (9%)
Query 199 AGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSLGLNPNHIHIYSASWG-PE 257
AG + N +C G + ++ V + R + + A+ G
Sbjct 374 AGNASNATNGNLCMTG-----TLIPEKVKGKIV---MCDRGINARVQKGDVVKAAGGVGM 425
Query 258 DDGKTVDGPARLAEEAFFRGVSQGRGGLGSI---FVWASGNGGREHD------SCNCDGY 308
T L +A + G I +V N
Sbjct 426 ILANTAANGEELVADAHLLPATTVGEKAGDIIRHYVTTDPNPTASISILGTVVGVKPSPV 485
Query 309 TNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTS 368
+ + +S T P + LA + + +D R+ +GTS
Sbjct 486 VAAFSSRGPNSITPNILKPDLIAPGVNILAAWTGAAGPTG---LASDSRRVEFNIISGTS 542
Query 369 ASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSH-SYGYG 427
S P +G+ AL + + ++ ++ T+ + + G+ + +G G
Sbjct 543 MSCPHVSGLAALLKSVHPEWSPAAIRSALMTTAYKTYKDGKPLLDIATGKPSTPFDHGAG 602
Query 428 LL 429
+
Sbjct 603 HV 604
>sp|P21849|TSA4_GIAIN Major surface-labeled trophozoite antigen
417 OS=Giardia intestinalis OX=5741 GN=TSA 417 PE=2 SV=1
Length=713
Score = 47.5 bits (111), Expect = 4e-04, Method: Composition-based stats.
Identities = 26/118 (22%), Positives = 35/118 (30%), Gaps = 37/118 (31%)
Query 571 YGTAPEGLPVPPESSG--CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYS 628
YG + E + CKT C C +GF
Sbjct 381 YGATEGAKKLCKECTAANCKTCDDQGQCQACNDGFYK----------------------- 417
Query 629 TENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASL----DPVEQTCSRQSQSS 682
C+PCH SC TC +DC CP+ +L D + TC +
Sbjct 418 --------NGDACSPCHESCKTCSAGTASDCTECPTGKALRYGDDGTKGTCGEGCTTG 467
Score = 44.8 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 34/163 (21%), Positives = 54/163 (33%), Gaps = 17/163 (10%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQKS---CVQHCPPGFAPQVLDTHYSTENDVETIRA 638
P + C + + C +G+ L + C + C D + V++ A
Sbjct 543 PGKTVCISAPNGGTCQKAADGYKLDSGTLTVCSEGC--KECASSTDCTTCLDGYVKS--A 598
Query 639 SVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPP--------QQQ 690
S C C ASC TC G A T C +C + + +S
Sbjct 599 SACTKCDASCETCNG-AATTCKACATGYYKTASGEGACTSCESDSNGVTGIKGCLNCAPP 657
Query 691 PPRLPPEVEAGQRLRAGLLPSHLP-EVVAGLSCAFIVLVFVTV 732
P + + S L +AG+S A IV+V +
Sbjct 658 PNNKGSVLCYLIKDSGSTNKSGLSTGAIAGISVAVIVVVGGLI 700
>sp|F4JJH5|SBT3C_ARATH Subtilisin-like protease SBT3.12 OS=Arabidopsis
thaliana OX=3702 GN=SBT3.12 PE=3 SV=1
Length=754
Score = 47.5 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 58/411 (14%), Positives = 115/411 (28%), Gaps = 80/411 (19%)
Query 8 LWVVAATGTLVLLAADA-QGQKVFTNTWAVRIPGGPA---VANSVARKHGFLNLGQIFGD 63
+ G V + + +K++ VR ++ + F +
Sbjct 16 FLFIVNVGFCVFAQESSNEERKIYVVHLGVRRHDDSELVSESHQRMLESVFESAEAARES 75
Query 64 YYHFWHRGVTKRSLSPHRPRHSRLQREPQVQWLEQQV-AKRRTKRDVYQEPTDPKFPQQW 122
+ +H G + + + +L P V + + ++ R P FP
Sbjct 76 IVYNYHHGFSGFAARLTDSQAKQLSDRPDVFSVAPNRKVELQSTRIYDYLGLSPSFPS-- 133
Query 123 YLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGIEKNHPDLAG----------------- 165
+ G +V+ LD G+ P
Sbjct 134 -------------GVLHESNMGSDLVIGFLDSGVWPESPAYNDEGLEPIPKHWKGKCVAG 180
Query 166 -NYDPGA--------------SFDVNDQDPDPQPRYTQMNDNRHGTRCAGEVAA--VANN 208
++DP FD N+ + + HGT + A+ V N
Sbjct 181 EDFDPAKHCNKKLVGAKYFTDGFDENNSGISEEDFMSPRGYRGHGTMVSSIAASSFVPNV 240
Query 209 GVCGV------GVAYNARIGGVRM------LDGEVTDAVEARSLGLNPNHIHIYSASWGP 256
G+ G A ARI ++ L V+A +N + + + S S
Sbjct 241 SYGGLAPGVMRGAAPKARIAMYKIVWDRALLMSSTATMVKAFDEAIN-DGVDVLSISLAS 299
Query 257 EDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGYTNSI-YTL 315
+ +D E F V G + + N G E N + L
Sbjct 300 AAPFRPIDSITGDLELGSFHAVM-----KGIPVIAGASNTGPE-----AYTVANVFPWML 349
Query 316 SISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTG 366
++++ +Y++ T K++ + + ++ T
Sbjct 350 TVAATNID--RTFYADMTFGNNITIIGQAQYTGKEVSAGLVYIEHYKTDTS 398
Score = 47.1 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 17/78 (22%), Positives = 34/78 (44%), Gaps = 2/78 (3%)
Query 359 KCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGR 418
TGTS + P+ AG++ L + + + ++ ++ T+ + G R
Sbjct 528 GGYFLGTGTSYATPVVAGLVVLLKALHPDWSPAALKSAIMTTAWKTDPSGEPIFAEGEPR 587
Query 419 KVSH--SYGYGLLDAGAM 434
K++ YG GL++A
Sbjct 588 KLADPFDYGAGLVNAERA 605
>sp|Q5XH36|CRE2A_XENLA Cysteine-rich with EGF-like domain protein
2-A OS=Xenopus laevis OX=8355 GN=creld2-a PE=2 SV=1
Length=361
Score = 46.7 bits (109), Expect = 6e-04, Method: Composition-based stats.
Identities = 23/104 (22%), Positives = 36/104 (35%), Gaps = 9/104 (9%)
Query 585 SGCKTLT--SSQACVVCEEGFSLHQKSCV--QHCPPGFAPQVLDTHYSTENDVETIRASV 640
CKT S++ C C+ G+ CV C D+ Y + +
Sbjct 199 QACKTCDGPSNEDCKECKNGWIKDDGKCVDLNEC-ASEESPCKDSQYCLNTEGSFL---- 253
Query 641 CAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRE 684
C C SC C G +C C + L + T + +S +
Sbjct 254 CKECDGSCLGCSGEGPENCKDCATGYVLLAEKCTDVDECDASEQ 297
Score = 43.7 bits (101), Expect = 0.006, Method: Composition-based stats.
Identities = 21/84 (25%), Positives = 36/84 (43%), Gaps = 7/84 (8%)
Query 609 SCVQHCPPGFAPQVLDTHYSTE-NDVETIRASVCAPCHASCATCQGPALTDCLSCPSHAS 667
C F + D ++S+E ND ++ C C+ +C TC GP+ DC C +
Sbjct 165 RCEAEYTGPFCLECADEYFSSERNDTYSL----CTACNQACKTCDGPSNEDCKECKNGWI 220
Query 668 LDPVEQTCSRQSQSSRESPPQQQP 691
D + C ++ + E P +
Sbjct 221 KD--DGKCVDLNECASEESPCKDS 242
>sp|Q9LLL8|SBT4E_ARATH Subtilisin-like protease SBT4.14 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.14 PE=2 SV=1
Length=749
Score = 47.1 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 55/319 (17%), Positives = 95/319 (30%), Gaps = 70/319 (22%)
Query 85 SRLQREPQVQWLEQQVAKRRTKRDVYQEPTDPKFPQQWYLSGVTQRDLNVKAAWAQGYTG 144
++L + +E + R+ Y++ K L +R L +
Sbjct 87 AKLSPHEAKKMMEMEEV-VSVSRNQYRKLHTTKSWDFVGLPLTAKRHLKAE--------- 136
Query 145 HGIVVSILDDGIEKNHPDLAG------------------------NYDPGASFDVNDQDP 180
+++ +LD GI + N GA + +D +
Sbjct 137 RDVIIGVLDTGITPDSESFLDHGLGPPPAKWKGSCGPYKNFTGCNNKIIGAKYFKHDGNV 196
Query 181 DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL 240
+ ++ + HGT + VA V G+A G V + ARS
Sbjct 197 PAGEVRSPIDIDGHGTHTSSTVAGVLVANASLYGIANGTARGAVPSARLAMYKVCWARSG 256
Query 241 GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGG-----LGSIFVWASGN 295
+ + I + DG + + A + S G G + V ++GN
Sbjct 257 CAD---MDILAGFEAAIHDGVEIISISIGGPIADYSSDSISVGSFHAMRKGILTVASAGN 313
Query 296 GGREHDSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTD 355
G SS T + PW +S + T+ S D
Sbjct 314 DGP-------------------SSGTVTNHEPWILTVAASGIDRTFKS---------KID 345
Query 356 LRQKCTESHTGTSASAPLA 374
L + S G S +P A
Sbjct 346 LGNGKSFSGMGISMFSPKA 364
Score = 45.2 bits (105), Expect = 0.003, Method: Composition-based stats.
Identities = 14/60 (23%), Positives = 25/60 (42%), Gaps = 4/60 (7%)
Query 354 TDLRQKCTES----HTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNAN 409
T L S +GTS + P AG+ A + + T ++ ++ ++KP N
Sbjct 518 TGLDGDTQFSKFTILSGTSMACPHVAGVAAYVKSFHPDWTPAAIKSAIITSAKPISRRVN 577
>sp|Q9FK76|SBT56_ARATH Subtilisin-like protease SBT5.6 OS=Arabidopsis
thaliana OX=3702 GN=SBT5.6 PE=2 SV=1
Length=791
Score = 47.1 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 34/208 (16%), Positives = 63/208 (30%), Gaps = 44/208 (21%)
Query 345 NQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQT---- 400
+ ++ D R ++GTS S P AG IAL + + ++ ++ T
Sbjct 555 GADSPSKMSVDQRVAGYNIYSGTSMSCPHVAGAIALLKAIHPKWSSAAIRSALMTTAWMT 614
Query 401 --------------SKPAHLNANDWATNGV---GRKVSHSYGYGLLDAGAMVALAQNWTT 443
+ P L + + G SY A + + N T
Sbjct 615 NDKKKPIQDTTGLPANPFALGSGHFRPTKAADPGLVYDASY-----RAYLLYGCSVNITN 669
Query 444 VAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGD-LA 502
+ P KC I + V ++ + + T++ G+ +
Sbjct 670 IDPTFKCPSKIPPGYNHNYPSIAVP-----------NLKKT--VTVKRTVTNVGTGNSTS 716
Query 503 IHLVS---PMGTRSTLLAARPHDYSADG 527
+L S P G S ++ G
Sbjct 717 TYLFSVKPPSG-ISVKAIPNILSFNRIG 743
>sp|Q60553|ERBB2_MESAU Receptor tyrosine-protein kinase erbB-2
OS=Mesocricetus auratus OX=10036 GN=ERBB2 PE=2 SV=1
Length=1254
Score = 47.1 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 37/222 (17%), Positives = 65/222 (29%), Gaps = 46/222 (21%)
Query 570 LYGTAPEGLPVPPESS--GCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHY 627
++ + L P + + + + F+ + HC Q ++ +
Sbjct 477 VHTVPWDQLFRNPHQALLHSGNPSEEECG---LKDFACYPLCAHGHCWGPGPTQCVNCSH 533
Query 628 STEND-------------VETIRASVCAPCHASC------ATCQGPALTDCLSCPSHASL 668
E + C PCH C TC G C +CP H
Sbjct 534 FLRGQECVKECRVWKGLPREYVNGKHCLPCHPECQPQNSTETCTGSEADQCTACP-HYKD 592
Query 669 DPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQR------------LRAGLLPSHLPEV 716
P C + S + P P+ E + L P+
Sbjct 593 SPF---CVARCPSGVKPDLSYMPIWKYPDEEGMCQPCPINCTHSCVDLDERGCPAEQRAS 649
Query 717 VAGLSCAFIVLVFVTVFLVLQLRSGFSFRG----VKVYTMDR 754
A + +V + +FLV+ + G + ++ YTM R
Sbjct 650 PA--TSIIATVVGILLFLVIGVVVGILIKRRRQKIRKYTMRR 689
>sp|Q9ZSP5|AIR3_ARATH Subtilisin-like protease SBT5.3 OS=Arabidopsis
thaliana OX=3702 GN=AIR3 PE=2 SV=1
Length=772
Score = 47.1 bits (110), Expect = 7e-04, Method: Composition-based stats.
Identities = 19/106 (18%), Positives = 38/106 (36%), Gaps = 4/106 (4%)
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWR 391
A ++ Y+ + D R+ + +GTS S P +GI L + +
Sbjct 527 APGVSVIAAYTGAVSPTNEQF--DPRRLLFNAISGTSMSCPHISGIAGLLKTRYPSWSPA 584
Query 392 DMQHLVVQTSKPAHLNANDWATNGVGRKVSH-SYGYGLLDAGAMVA 436
++ ++ T+ + N K + S+G G + V
Sbjct 585 AIRSAIMTTATIMD-DIPGPIQNATNMKATPFSFGAGHVQPNLAVN 629
>sp|Q6UXH1|CREL2_HUMAN Protein disulfide isomerase CRELD2 OS=Homo
sapiens OX=9606 GN=CRELD2 PE=1 SV=1
Length=353
Score = 46.0 bits (107), Expect = 9e-04, Method: Composition-based stats.
Identities = 32/165 (19%), Positives = 52/165 (32%), Gaps = 24/165 (15%)
Query 575 PEGLPVPPESSGCKTLT--SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEND 632
CKT + +++ C CE G+ L + +CV P +N
Sbjct 191 ETHSICTACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNA 250
Query 633 VETIRASVCAPCHASCATCQGPALTDCLSCPSHASLD-----------PVEQTCSRQSQS 681
+ C C +SC C G +C C S + + E+TC R++++
Sbjct 251 NGSY---TCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDECSLAEKTCVRKNEN 307
Query 682 SRESPPQQQPPRLPPEVE--------AGQRLRAGLLPSHLPEVVA 718
+P E A G P+ LP
Sbjct 308 CYNTPGSYVCVCPDGFEETEDACVPPAEAEATEGESPTQLPSRED 352
Score = 42.5 bits (98), Expect = 0.011, Method: Composition-based stats.
Identities = 25/118 (21%), Positives = 34/118 (29%), Gaps = 4/118 (3%)
Query 576 EGLPVPPESSGCKTLTSSQACVVCE-EGFSLHQKSCVQHCPPGFAPQ-VLDTHYSTENDV 633
P+ C+ + G Q C G+ D + +
Sbjct 129 SPGTYGPDCLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGPLCTDCMDGYFSSL 188
Query 634 ETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQP 691
S+C C SC TC G DC C LD E C + + E PP
Sbjct 189 RNETHSICTACDESCKTCSGLTNRDCGECEVGWVLD--EGACVDVDECAAEPPPCSAA 244
>sp|P04412|EGFR_DROME Epidermal growth factor receptor OS=Drosophila
melanogaster OX=7227 GN=Egfr PE=1 SV=3
Length=1426
Score = 46.3 bits (108), Expect = 0.001, Method: Composition-based stats.
Identities = 19/85 (22%), Positives = 23/85 (27%), Gaps = 23/85 (27%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVC 641
PE C + + CV CP VC
Sbjct 625 PECRTCNGAGADHCQECVH---VRDGQHCVSECPKNKYND----------------RGVC 665
Query 642 APCHASCATCQGPALT----DCLSC 662
CHA+C C GP T C +C
Sbjct 666 RECHATCDGCTGPKDTIGIGACTTC 690
Score = 44.4 bits (103), Expect = 0.005, Method: Composition-based stats.
Identities = 32/153 (21%), Positives = 48/153 (31%), Gaps = 22/153 (14%)
Query 587 CKTLTS----SQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCA 642
C+ T+ Q C C ++ C CP HY+ E E C
Sbjct 744 CELCTNYGYHEQVCSKC--THYKRREQCETECP--------ADHYTDEEQRE------CF 787
Query 643 PCHASCATCQGPALTDCLSCPSHASLDPVEQT-CSRQSQSSRESPPQQQPPRLPPEVEAG 701
H C C GP DC SC + D E + + S + + + A
Sbjct 788 QRHPECNGCTGPGADDCKSCRNFKLFDANETGPYVNSTMFNCTSKCPLEMRHVNYQYTAI 847
Query 702 QRLRAGLLPSHLPEVVAGLSCAFIVLVFVTVFL 734
A P ++ A L I ++ V +
Sbjct 848 GPYCAASPPRS-SKITANLDVNMIFIITGAVLV 879
Score = 42.5 bits (98), Expect = 0.018, Method: Composition-based stats.
Identities = 23/115 (20%), Positives = 32/115 (28%), Gaps = 14/115 (12%)
Query 584 SSGCKTLTSS---QACVVCEE---GFSLHQKSC---VQHCPPGFAPQVLDTHYSTENDVE 634
GC + AC C K C CP G+ H + ++
Sbjct 672 CDGCTGPKDTIGIGACTTCNLAIINNDATVKRCLLKDDKCPDGYFW--EYVHPQEQGSLK 729
Query 635 TIRAS-VCAPCHASCATC--QGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESP 686
+ VC CH C C G C C + + E C + E
Sbjct 730 PLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQR 784
Score = 41.7 bits (96), Expect = 0.030, Method: Composition-based stats.
Identities = 20/121 (17%), Positives = 31/121 (26%), Gaps = 14/121 (12%)
Query 575 PEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQ-HCPPGFAPQVLDTHYSTEN-- 631
+ PE + + +CE+ ++ C + C Q L N
Sbjct 544 WPAIQKEPEQKVW--VNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGT 601
Query 632 ---------DVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
+ C CH C TC G C C C + +
Sbjct 602 CIADCGYISNAYKFDNRTCKICHPECRTCNGAGADHCQECVHVRDGQHCVSECPKNKYND 661
Query 683 R 683
R
Sbjct 662 R 662
>sp|P70424|ERBB2_MOUSE Receptor tyrosine-protein kinase erbB-2
OS=Mus musculus OX=10090 GN=Erbb2 PE=1 SV=3
Length=1256
Score = 46.0 bits (107), Expect = 0.001, Method: Composition-based stats.
Identities = 27/121 (22%), Positives = 37/121 (31%), Gaps = 26/121 (21%)
Query 586 GCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCH 645
C +Q CV C + L + CV+ C E +R C PCH
Sbjct 520 HCWGPGPTQ-CVNCSQ--FLRGQECVEECRVWKGLP-----------REYVRGKHCLPCH 565
Query 646 ASC------ATCQGPALTDCLSC-PSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEV 698
C TC G C +C S +C + S + P P+
Sbjct 566 PECQPQNSSETCYGSEADQCEACAHYKDS-----SSCVARCPSGVKPDLSYMPIWKYPDE 620
Query 699 E 699
E
Sbjct 621 E 621
>sp|F4IG09|SBT41_ARATH Subtilisin-like protease SBT4.1 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.1 PE=3 SV=1
Length=775
Score = 46.0 bits (107), Expect = 0.002, Method: Composition-based stats.
Identities = 31/211 (15%), Positives = 61/211 (29%), Gaps = 50/211 (24%)
Query 148 VVSILDDGIEKNHPDLAG--------------------NYDPGASFDVNDQDPDPQPRYT 187
VV+++D GI + +L G S+ + +
Sbjct 131 VVAVIDSGI-WPYSELFGSDSPPPPGWENKCENITCNNKIVGARSYYPKKEKYKWVEEKS 189
Query 188 QMNDNRHGTRCAGEVAAVANNGVCGVGVA--------YNARIGGV----RMLDGEVTDAV 235
++ HGT A VA G+A NA+I R++ +
Sbjct 190 VIDVTGHGTHVASIVAGRKVEKAGYFGLAEGTMRGGVPNAKIAVYKTCWRVIRKNGREDS 249
Query 236 EARSLGLN-------PNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSI 288
R + + + I S S G + D + A G +
Sbjct 250 VCREDNILKAIDDAIADKVDIISYSQGFQFTPLQKDKVSWAFLRALKN---------GIL 300
Query 289 FVWASGNGGREHDSCNCDGYTNSIYTLSISS 319
A+GN + + + +++++
Sbjct 301 TSAAAGN-YANNGKFYYTVANGAPWVMTVAA 330
Score = 42.5 bits (98), Expect = 0.017, Method: Composition-based stats.
Identities = 30/165 (18%), Positives = 56/165 (34%), Gaps = 21/165 (13%)
Query 332 ACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWR 391
A + + + D R +GTS + P A G +AL L++ K +
Sbjct 515 APGLDIIAGWPENVKLSSDRPANDYRHLRFNIMSGTSMACPHATG-LALYLKSFKRWSPS 573
Query 392 DMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTVAPQRKCI 451
++ ++ TS + N++A YG G L+A ++ V
Sbjct 574 AIKSALMTTSSEMTDDDNEFA-----------YGSGHLNATK----VRDPGLVYETH--Y 616
Query 452 IDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYN 496
D + +G E ++ T ++H L+Y
Sbjct 617 QDYIDYLCKLGYNTEKLRSHVGSDKIDCSKTEIDH---DADLNYP 658
>sp|Q4G063|CREL2_RAT Protein disulfide isomerase Creld2 OS=Rattus
norvegicus OX=10116 GN=Creld2 PE=1 SV=1
Length=349
Score = 45.2 bits (105), Expect = 0.002, Method: Composition-based stats.
Identities = 26/109 (24%), Positives = 38/109 (35%), Gaps = 6/109 (6%)
Query 582 PESSGCKTLTSSQACV--VCEEGFSLHQKSCVQHCPPGFAPQ-VLDTHYSTENDVETIRA 638
P+ C+ + C S Q C G+ +D +
Sbjct 132 PDCKECQGGSERPCSGNGYCSGDGS-RQGDGSCQCHAGYKGPLCIDCMDGYFSLQRNETH 190
Query 639 SVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPP 687
S+C C SC TC GP+ DC+ C VE C + + E+PP
Sbjct 191 SICLACDESCKTCSGPSNKDCVQC--EVGWARVEDACVDVDECAAETPP 237
Score = 42.5 bits (98), Expect = 0.011, Method: Composition-based stats.
Identities = 21/117 (18%), Positives = 36/117 (31%), Gaps = 5/117 (4%)
Query 579 PVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRA 638
P E+ C+ + S C C+ +C A + + D ++
Sbjct 236 PPCSEAQYCENVNGSYICEECDSTCVGCTGKGPANCKECIAGYTKQSGQCADIDECSLEE 295
Query 639 SVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLP 695
C + +C G C+ CP + E C + +QS QP
Sbjct 296 KACKRRNENCYNVPGSF--VCV-CPDG--FEETEDACVQTAQSEVTEENPTQPLSHE 347
>sp|P06494|ERBB2_RAT Receptor tyrosine-protein kinase erbB-2 OS=Rattus
norvegicus OX=10116 GN=Erbb2 PE=1 SV=3
Length=1257
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 23/150 (15%), Positives = 39/150 (26%), Gaps = 25/150 (17%)
Query 570 LYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
++ + L P + + + + G + HC Q ++ +
Sbjct 478 VHTVPWDQLFRNPHQALLHSGNRPEEDLCVSSGLVCNSLCAHGHCWGPGPTQCVNCSHFL 537
Query 630 ENDVETIRASV-------------CAPCHASC------ATCQGPALTDCLSC-PSHASLD 669
V C PCH C TC G C +C S
Sbjct 538 RGQECVEECRVWKGLPREYVSDKRCLPCHPECQPQNSSETCFGSEADQCAACAHYKDS-- 595
Query 670 PVEQTCSRQSQSSRESPPQQQPPRLPPEVE 699
+C + S + P P+ E
Sbjct 596 ---SSCVARCPSGVKPDLSYMPIWKYPDEE 622
>sp|Q5RB22|ERBB3_PONAB Receptor tyrosine-protein kinase erbB-3
OS=Pongo abelii OX=9601 GN=ERBB3 PE=2 SV=1
Length=1342
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 19/80 (24%), Positives = 24/80 (30%), Gaps = 10/80 (13%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
++ C S CV CP G + C P
Sbjct 562 TATCNGSGSDTCAQCAH---FRDGPHCVSSCPHGVLGA------KGPIYKYPDVQNECRP 612
Query 644 CHASCAT-CQGPALTDCLSC 662
CH +C C+GP L DCL
Sbjct 613 CHENCTQGCKGPELQDCLGQ 632
Score = 43.3 bits (100), Expect = 0.010, Method: Composition-based stats.
Identities = 35/166 (21%), Positives = 54/166 (33%), Gaps = 27/166 (16%)
Query 552 ENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCV 611
N+S A LT+ T +L G G+ + C T +V + + K
Sbjct 125 TNSSHALRQLRLTQLTEILSG----GVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNG 180
Query 612 QHCPPGFAPQVLDTHYSTENDVETIRASVCAP--------------CHASCA-TCQGPAL 656
+ CPP S D +T+ ++CAP CH CA C GP
Sbjct 181 KSCPPCHEVCKGRCWGSGPEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQD 240
Query 657 TDCLSCPSHASLDPVEQTCSRQSQSS----RESPPQQQPPRLPPEV 698
TDC +C C + + + + P +
Sbjct 241 TDCFACRHFND----SGACVPRCPQPLVYNKLTFQLEPNPHTKYQY 282
>sp|P92127|VS41_GIAIN Variant-specific surface protein VSP4A1
OS=Giardia intestinalis OX=5741 PE=1 SV=1
Length=687
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 26/90 (29%), Positives = 36/90 (40%), Gaps = 7/90 (8%)
Query 596 CVVCEEGFSLHQKSCVQHCPPGFAPQVLDT-HYSTENDVETIRAS--VCAPCHASCATCQ 652
C++C + + V +C AP TE T + S CA CH+ CATC
Sbjct 141 CILCWDTTDRNGVMGVANCATCTAPASSTGPATCTECMAGTYKKSDTECAACHSDCATCS 200
Query 653 GPALTDCLSCPSHASLD----PVEQTCSRQ 678
G A C SC + L + TC+
Sbjct 201 GEANNQCTSCETGKYLKSNQCVEKNTCNTN 230
Score = 40.2 bits (92), Expect = 0.096, Method: Composition-based stats.
Identities = 27/115 (23%), Positives = 36/115 (31%), Gaps = 26/115 (23%)
Query 581 PPESSGCKTLTSSQA---------CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEN 631
+ C S A C CE G L CV+ HY +
Sbjct 183 KKSDTECAACHSDCATCSGEANNQCTSCETGKYLKSNQCVE------KNTCNTNHYPDDT 236
Query 632 DVETIRASVCAPCHASCATCQGPALT---DCLSCP----SHASLDPVEQTCSRQS 679
++ C A+CATC + T CL+C +LD TC S
Sbjct 237 ---SMTCVACTVLDANCATCSFDSATAKGKCLTCNSNKIPRTTLDG-TSTCVENS 287
>sp|P21860|ERBB3_HUMAN Receptor tyrosine-protein kinase erbB-3
OS=Homo sapiens OX=9606 GN=ERBB3 PE=1 SV=1
Length=1342
Score = 45.6 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 19/80 (24%), Positives = 24/80 (30%), Gaps = 10/80 (13%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
++ C S CV CP G + C P
Sbjct 562 TATCNGSGSDTCAQCAH---FRDGPHCVSSCPHGVLGA------KGPIYKYPDVQNECRP 612
Query 644 CHASCAT-CQGPALTDCLSC 662
CH +C C+GP L DCL
Sbjct 613 CHENCTQGCKGPELQDCLGQ 632
Score = 41.7 bits (96), Expect = 0.033, Method: Composition-based stats.
Identities = 34/166 (20%), Positives = 53/166 (32%), Gaps = 27/166 (16%)
Query 552 ENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCV 611
N+S A LT+ T +L G G+ + C T +V + + K
Sbjct 125 TNSSHALRQLRLTQLTEILSG----GVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNG 180
Query 612 QHCPPGFAPQVLDTHYSTENDVETIRASVCAP--------------CHASCA-TCQGPAL 656
+ CPP D +T+ ++CAP CH CA C GP
Sbjct 181 RSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQD 240
Query 657 TDCLSCPSHASLDPVEQTCSRQSQSS----RESPPQQQPPRLPPEV 698
TDC +C C + + + + P +
Sbjct 241 TDCFACRHFND----SGACVPRCPQPLVYNKLTFQLEPNPHTKYQY 282
>sp|P25119|TNR1B_MOUSE Tumor necrosis factor receptor superfamily
member 1B OS=Mus musculus OX=10090 GN=Tnfrsf1b PE=2 SV=1
Length=474
Score = 44.8 bits (104), Expect = 0.002, Method: Composition-based stats.
Identities = 31/117 (26%), Positives = 46/117 (39%), Gaps = 12/117 (10%)
Query 566 FTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDT 625
F L L+ T +P + K C + +E + + C CPPG +
Sbjct 12 FELQLWATG-HTVPAQVVLTPYK-PEPGYECQISQEYYDRKAQMCCAKCPPGQYVK---- 65
Query 626 HYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVE-QTCSRQSQS 681
H+ + +VCA C AS T CLSC S + D VE + C++Q
Sbjct 66 HFCNKTS-----DTVCADCEASMYTQVWNQFRTCLSCSSSCTTDQVEIRACTKQQNR 117
>sp|Q1RMU1|RSPO3_BOVIN R-spondin-3 OS=Bos taurus OX=9913 GN=RSPO3
PE=2 SV=1
Length=273
Score = 44.4 bits (103), Expect = 0.002, Method: Composition-based stats.
Identities = 32/159 (20%), Positives = 50/159 (31%), Gaps = 18/159 (11%)
Query 571 YGTA-PEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
YGT P+ + C T + C C+ GF LH C+ +CP G +
Sbjct 85 YGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYLHLGKCLDNCPEGLEANNHTMECVS 144
Query 630 ENDVETIRASVCAPCHASCATCQGPALTDCLS-------------CPSHASLDPV---EQ 673
E S +PC TC T+ CP + +
Sbjct 145 IVHCEASEWSPWSPCTKKGKTCGFKRGTETRVREIIQHPSAKGNLCPPTSEARKCTVQRK 204
Query 674 TCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSH 712
C + + + +++ P +A GL PS
Sbjct 205 KCPKGERGRKGRERKRKKPNKEESKDAIPD-NKGLEPSR 242
>sp|Q4V7M2|CRE2B_XENLA Cysteine-rich with EGF-like domain protein
2-B OS=Xenopus laevis OX=8355 GN=creld2-b PE=2 SV=1
Length=361
Score = 44.4 bits (103), Expect = 0.003, Method: Composition-based stats.
Identities = 20/82 (24%), Positives = 27/82 (33%), Gaps = 9/82 (11%)
Query 585 SGCKTLT--SSQACVVCEEGFSLHQKSCV--QHCPPGFAPQVLDTHYSTENDVETIRASV 640
CKT S++ C C G+ CV C D+ Y + +
Sbjct 199 QACKTCNGPSNEDCKECNNGWVKDDGKCVDLNEC-ASEESPCKDSQYCLNTEGSFL---- 253
Query 641 CAPCHASCATCQGPALTDCLSC 662
C C SC+ C G C C
Sbjct 254 CKECDGSCSGCSGEGPESCKDC 275
Score = 44.0 bits (102), Expect = 0.004, Method: Composition-based stats.
Identities = 26/122 (21%), Positives = 43/122 (35%), Gaps = 22/122 (18%)
Query 587 CKTLTSSQACVVCEEGFS--LHQK---------------SCVQHCPPGFAPQVLDTHYST 629
C + + C+ C G H C F + D +YS+
Sbjct 126 CPSGSYGPDCLACLGGSERPCHGNGFCSGDGTRSGDGSCRCKAEYTGSFCLECSDGYYSS 185
Query 630 ENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQ 689
E + +VC C+ +C TC GP+ DC C + D + C ++ + E P +
Sbjct 186 ERN---DTHAVCIACNQACKTCNGPSNEDCKECNNGWVKD--DGKCVDLNECASEESPCK 240
Query 690 QP 691
Sbjct 241 DS 242
>sp|Q2I0M5|RSPO4_HUMAN R-spondin-4 OS=Homo sapiens OX=9606 GN=RSPO4
PE=1 SV=2
Length=234
Score = 43.7 bits (101), Expect = 0.003, Method: Composition-based stats.
Identities = 20/118 (17%), Positives = 34/118 (29%), Gaps = 33/118 (28%)
Query 584 SSGCKTLTSSQACVVCEEGFSL--------HQKSCVQHCPPGFAPQVLDTHYSTENDVET 635
+GC + C C++ L C+ CPPG+ +
Sbjct 35 CTGCIICSEENGCSTCQQRLFLFIRREGIRQYGKCLHDCPPGYFG------------IRG 82
Query 636 IRASVCAPCHASCATCQG-----PALTD-------CL-SCPSHASLDPVEQTCSRQSQ 680
+ C C A+C +C CL +CP + C + +
Sbjct 83 QEVNRCKKCGATCESCFSQDFCIRCKRQFYLYKGKCLPTCPPGTLAHQNTRECQGECE 140
Score = 38.6 bits (88), Expect = 0.14, Method: Composition-based stats.
Identities = 24/118 (20%), Positives = 42/118 (36%), Gaps = 3/118 (3%)
Query 575 PEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
E + C++ S C+ C+ F L++ C+ CPPG E ++
Sbjct 83 QEVNRCKKCGATCESCFSQDFCIRCKRQFYLYKGKCLPTCPPGTLAHQNTRECQGECELG 142
Query 635 TIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPP 692
+PC + TC + + + TC + SR+ P Q+ P
Sbjct 143 PW--GGWSPCTHNGKTCGSAWGLESRVREAGRAGHEEAATC-QVLSESRKCPIQRPCP 197
>sp|P24348|LET23_CAEEL Receptor tyrosine-protein kinase let-23
OS=Caenorhabditis elegans OX=6239 GN=let-23 PE=1 SV=3
Length=1323
Score = 44.8 bits (104), Expect = 0.004, Method: Composition-based stats.
Identities = 17/111 (15%), Positives = 29/111 (26%), Gaps = 7/111 (6%)
Query 576 EGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVET 635
E + + + C + + C+ C + T+ +
Sbjct 506 ENRDSKLCETEQRVCDKNCNKRGC---WGKEPEDCL-ECKTWKSVGTCVEKCDTKGFLRN 561
Query 636 IRASVCAPCHASCATCQGPALTDCLSCPSHASLD---PVEQTCSRQSQSSR 683
+ C C C TC G DCL+C + C S
Sbjct 562 QTSMKCERCSPECETCNGLGELDCLTCRHKTLYNSDFGNRMECVHDCPVSH 612
Score = 44.4 bits (103), Expect = 0.006, Method: Composition-based stats.
Identities = 26/149 (17%), Positives = 46/149 (31%), Gaps = 16/149 (11%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
S+G + + C E + ++ C+ CP V +VC
Sbjct 705 SAGRNVVQNKCVCKHVEYQPNPSERICMDQCPVNSFM------------VPDTNNTVCKK 752
Query 644 CHASC---ATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEA 700
CH C C T C C + C + + L ++ +
Sbjct 753 CHHECDQNYHCANGQSTGCQKCKNFTVFKGDIAQCVSECPKNLPFSNPANGECLDYDIAS 812
Query 701 GQRLRAGLLPSHLPEVVAGLSCAFIVLVF 729
QR ++ + A + FI+LV+
Sbjct 813 RQRKTRMVIIGSVLFGFAVMF-LFILLVY 840
Score = 41.7 bits (96), Expect = 0.036, Method: Composition-based stats.
Identities = 29/179 (16%), Positives = 47/179 (26%), Gaps = 36/179 (20%)
Query 538 SWDEDPSG-----EWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTS 592
W ++P W + + G L T+ + PE C L
Sbjct 529 CWGKEPEDCLECKTWKSVGTCVEKCDTKGFLRN------QTSMKCERCSPECETCNGLGE 582
Query 593 SQACVVCEEGFSL----HQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASC 648
+ ++ CV CP +H+ T+ +VC CH +C
Sbjct 583 LDCLTCRHKTLYNSDFGNRMECVHDCP--------VSHFPTQ-------KNVCEKCHPTC 627
Query 649 AT--CQGPALT----DCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAG 701
C GP C C + C + S + P +
Sbjct 628 YDNGCTGPDSNLGYGGCKQCKYAVKYENDTIFCLQSSGMNNVCVENDLPNYYISTYDTE 686
>sp|Q60438|CREL2_CRIGR Protein disulfide isomerase CRELD2 OS=Cricetulus
griseus OX=10029 GN=CRELD2 PE=2 SV=1
Length=348
Score = 44.0 bits (102), Expect = 0.004, Method: Composition-based stats.
Identities = 24/108 (22%), Positives = 36/108 (33%), Gaps = 4/108 (4%)
Query 582 PESSGCKTLTSSQACVVCE-EGFSLHQKSCVQHCPPGFAPQ-VLDTHYSTENDVETIRAS 639
P+ C+ + +G Q C G+ +D + + S
Sbjct 134 PDCQECQGGSQRPCSGNGHCDGDGSRQGDGSCQCHVGYKGPLCIDCMDGYFSLLRNETHS 193
Query 640 VCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPP 687
C C SC TC GP C+ C VE C + + E+PP
Sbjct 194 FCTACDESCKTCSGPTNKGCVEC--EVGWTRVEDACVDVDECAAETPP 239
Score = 41.7 bits (96), Expect = 0.022, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 36/88 (41%), Gaps = 9/88 (10%)
Query 584 SSGCKTLT--SSQACVVCEEGFSLHQKSC--VQHCPPGFAPQVLDTHYSTENDVETIRAS 639
CKT + +++ CV CE G++ + +C V C P + Y + +
Sbjct 199 DESCKTCSGPTNKGCVECEVGWTRVEDACVDVDEC-AAETPPCSNVQYCENVNG----SY 253
Query 640 VCAPCHASCATCQGPALTDCLSCPSHAS 667
C C ++C C G +C C S S
Sbjct 254 TCEECDSTCVGCTGKGPANCKECISGYS 281
>sp|Q55CT0|TPP1_DICDI Tripeptidyl-peptidase 1 OS=Dictyostelium
discoideum OX=44689 GN=tpp1 PE=3 SV=1
Length=600
Score = 44.0 bits (102), Expect = 0.005, Method: Composition-based stats.
Identities = 49/248 (20%), Positives = 90/248 (36%), Gaps = 55/248 (22%)
Query 238 RSLGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGG 297
L NP ++S S+G +D+ + F + + GR V++SG+ G
Sbjct 355 VDLSSNPKLPLVHSISYG-DDESSIGLAYTDRVDTEFKKYAAMGR-----TIVFSSGDFG 408
Query 298 RE-HDSCNC--DGY-TNSIYTLSISSA------------------TQFGNVPWY-SEACS 334
+D C+ G+ +S + L++ + + + PWY + CS
Sbjct 409 VGCNDDCDSFSPGWPASSRFVLAVGGVIKKKDGSIIGDEISGGGFSNYFSRPWYQVDECS 468
Query 335 S-------TLATTYSSGNQNEKQIVT-----TDLRQKCTESHTGTSASAPLAAGIIALT- 381
S +L++ Y+ + I + L + GTSASAP+ AG+++L
Sbjct 469 SYIEWLNGSLSSFYNQSGRGFPDISSFSENVVILYKDKLMPIGGTSASAPIIAGLLSLIN 528
Query 382 ---LEANK------NLTWRDMQHLVVQTSKPAHLNANDWATNGVGRK----VSHSYGYGL 428
L+ N+ N + + N++ G K G GL
Sbjct 529 DQRLQKNQSPIGLFNPLLYKIARDHPNSFLDIDFGENNYKCCTNGFKSKSGWDPVTGLGL 588
Query 429 LDAGAMVA 436
+ +V
Sbjct 589 PNFDELVK 596
>sp|Q9BXY4|RSPO3_HUMAN R-spondin-3 OS=Homo sapiens OX=9606 GN=RSPO3
PE=1 SV=1
Length=272
Score = 43.3 bits (100), Expect = 0.006, Method: Composition-based stats.
Identities = 30/162 (19%), Positives = 50/162 (31%), Gaps = 17/162 (10%)
Query 571 YGTA-PEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
YGT P+ + C T + C C+ GF LH C+ +CP G +
Sbjct 85 YGTRYPDINKCTKCKADCDTCFNKNFCTKCKSGFYLHLGKCLDNCPEGLEANNHTMECVS 144
Query 630 ENDVETIRASVCAPCHASCATCQGPALTDCLS-------------CPSHASLDPV---EQ 673
E + +PC TC T+ CP +
Sbjct 145 IVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREIIQHPSAKGNLCPPTNETRKCTVQRK 204
Query 674 TCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPE 715
C + + + +++ P EA ++ +PE
Sbjct 205 KCQKGERGKKGRERKRKKPNKGESKEAIPDSKSLESSKEIPE 246
>sp|Q61526|ERBB3_MOUSE Receptor tyrosine-protein kinase erbB-3
OS=Mus musculus OX=10090 GN=Erbb3 PE=1 SV=2
Length=1339
Score = 44.0 bits (102), Expect = 0.006, Method: Composition-based stats.
Identities = 25/104 (24%), Positives = 33/104 (32%), Gaps = 9/104 (9%)
Query 560 YGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFA 619
G +F + + P E + + S AC C CV CP G
Sbjct 537 QGEPREFVHEAHCFSCHPECQPMEGTSTCNGSGSDACARC--AHFRDGPHCVNSCPHGIL 594
Query 620 PQVLDTHYSTENDVETIRASVCAPCHASCAT-CQGPALTDCLSC 662
+ C PCH +C C+GP L DCL
Sbjct 595 GA------KGPIYKYPDAQNECRPCHENCTQGCKGPELQDCLGQ 632
Score = 41.3 bits (95), Expect = 0.037, Method: Composition-based stats.
Identities = 20/105 (19%), Positives = 33/105 (31%), Gaps = 23/105 (22%)
Query 613 HCPPGFAPQVLDTHYSTENDVETIRASVCAP--------------CHASCA-TCQGPALT 657
+CPP D + + ++CAP CH CA C GP T
Sbjct 182 NCPPCHEVCKGRCWGPGPEDCQILTKTICAPQCNGRCFGPNPNQCCHDECAGGCSGPQDT 241
Query 658 DCLSCPSHASLDPVEQTCSRQSQSS----RESPPQQQPPRLPPEV 698
DC +C C + + + + + P + +
Sbjct 242 DCFACRHFND----SGACVPRCPAPLVYNKLTFQLEPNPHIKYQY 282
>sp|Q62799|ERBB3_RAT Receptor tyrosine-protein kinase erbB-3 OS=Rattus
norvegicus OX=10116 GN=Erbb3 PE=1 SV=3
Length=1339
Score = 43.7 bits (101), Expect = 0.007, Method: Composition-based stats.
Identities = 24/89 (27%), Positives = 28/89 (31%), Gaps = 11/89 (12%)
Query 575 PEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
PE LP+ +S C S CV CP G
Sbjct 554 PECLPMEG-TSTCNGSGSDACARCAH---FRDGPHCVNSCPHGILGA------KGPIYKY 603
Query 635 TIRASVCAPCHASCAT-CQGPALTDCLSC 662
+ C PCH +C C GP L DCL
Sbjct 604 PDAQNECRPCHENCTQGCNGPELQDCLGQ 632
Score = 42.9 bits (99), Expect = 0.015, Method: Composition-based stats.
Identities = 33/166 (20%), Positives = 53/166 (32%), Gaps = 27/166 (16%)
Query 552 ENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCV 611
N+S A T+ T +L G G+ + C T +V G + K+
Sbjct 125 TNSSHALRQLKFTQLTEILSG----GVYIEKNDKLCHMDTIDWRDIVRVRGAEIVVKNNG 180
Query 612 QHCPPGFAPQVLDTHYSTENDVETIRASVCAP--------------CHASCA-TCQGPAL 656
+CPP +D + + ++CAP CH CA C GP
Sbjct 181 ANCPPCHEVCKGRCWGPGPDDCQILTKTICAPQCNGRCFGPNPNQCCHDECAGGCSGPQD 240
Query 657 TDCLSCPSHASLDPVEQTCSRQSQSS----RESPPQQQPPRLPPEV 698
TDC +C C + + + + P +
Sbjct 241 TDCFACRRFND----SGACVPRCPEPLVYNKLTFQLEPNPHTKYQY 282
Score = 36.7 bits (83), Expect = 0.97, Method: Composition-based stats.
Identities = 19/114 (17%), Positives = 26/114 (23%), Gaps = 20/114 (18%)
Query 565 KFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLD 624
+T +L G + E L + EG C Q L
Sbjct 469 NWTRLLRGPSEERLDIK---------YDRPLGECLAEGKVCDPLCSSGGCWGPGPGQCLS 519
Query 625 THYSTENDVETIRASVCAPCHASCATCQGP---ALTDCLSCPSHASLDPVEQTC 675
+ R VC H + + C SC TC
Sbjct 520 CRNYS-------REGVCVT-HCNFLQGEPREFVHEAQCFSCHPECLPMEGTSTC 565
>sp|P04626|ERBB2_HUMAN Receptor tyrosine-protein kinase erbB-2
OS=Homo sapiens OX=9606 GN=ERBB2 PE=1 SV=1
Length=1255
Score = 43.7 bits (101), Expect = 0.008, Method: Composition-based stats.
Identities = 24/101 (24%), Positives = 32/101 (32%), Gaps = 23/101 (23%)
Query 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTEND-------------VETIRASVCAPCHAS 647
EG + HQ HC Q ++ E + A C PCH
Sbjct 507 EGLACHQLCARGHCWGPGPTQCVNCSQFLRGQECVEECRVLQGLPREYVNARHCLPCHPE 566
Query 648 CA------TCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C TC GP C++C +H P C + S
Sbjct 567 CQPQNGSVTCFGPEADQCVAC-AHYKDPPF---CVARCPSG 603
>sp|Q9CYA0|CREL2_MOUSE Protein disulfide isomerase Creld2 OS=Mus
musculus OX=10090 GN=Creld2 PE=1 SV=1
Length=350
Score = 43.3 bits (100), Expect = 0.008, Method: Composition-based stats.
Identities = 25/112 (22%), Positives = 38/112 (34%), Gaps = 6/112 (5%)
Query 582 PESSGCKTLTSSQACV--VCEEGFSLHQKSCVQHCPPGFAPQ-VLDTHYSTENDVETIRA 638
P+ C+ + C S Q C G+ +D +
Sbjct 133 PDCQECQGGSERPCSGNGYCSGDGS-RQGDGSCQCHTGYKGPLCIDCTDGFFSLQRNETH 191
Query 639 SVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQ 690
S+C+ C SC TC GP+ DC+ C VE C + + E+ P
Sbjct 192 SICSACDESCKTCSGPSNKDCIQC--EVGWARVEDACVDVDECAAETSPCSD 241
Score = 41.7 bits (96), Expect = 0.020, Method: Composition-based stats.
Identities = 19/112 (17%), Positives = 36/112 (32%), Gaps = 5/112 (4%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVC 641
+ C+ + S C C+ +C A ++ T+ D ++ C
Sbjct 240 SDGQYCENVNGSYTCEDCDSTCVGCTGKGPANCKECIAGYTKESGQCTDIDECSLEEKAC 299
Query 642 APCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPR 693
+ +C G C+ CP + E C + ++ QPP
Sbjct 300 KRKNENCYNVPGSF--VCV-CPEG--FEETEDACVQTAEGKVTEENPTQPPS 346
>sp|Q2KIT5|CREL2_BOVIN Protein disulfide isomerase CRELD2 OS=Bos
taurus OX=9913 GN=CRELD2 PE=2 SV=1
Length=351
Score = 42.9 bits (99), Expect = 0.009, Method: Composition-based stats.
Identities = 25/99 (25%), Positives = 35/99 (35%), Gaps = 9/99 (9%)
Query 573 TAPEGLPVPPESSGCKTLT--SSQACVVCEEGFSLHQKSCVQ--HCPPGFAPQVLDTHYS 628
T+ CKT +++ C CE G+ +CV C P DT Y
Sbjct 186 TSETHSICSACDEACKTCVGPTNRDCGQCEVGWVRQDDACVDVDEC-AAEPPPCEDTQYC 244
Query 629 TENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHAS 667
+ + VC C +C C G T C C + S
Sbjct 245 ENVNG----SFVCEECDPTCMGCTGKGPTQCRECIAGYS 279
Score = 38.6 bits (88), Expect = 0.17, Method: Composition-based stats.
Identities = 26/124 (21%), Positives = 37/124 (30%), Gaps = 17/124 (14%)
Query 568 LVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHY 627
L G + G T +C C G+ C F +TH
Sbjct 135 LACQGGSERPCSGNGHCVGDGTREGDGSCQ-CHLGY--QGPLCSDCMDGYFRSPTSETH- 190
Query 628 STENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPP 687
S+C+ C +C TC GP DC C + C + + E PP
Sbjct 191 -----------SICSACDEACKTCVGPTNRDCGQC--EVGWVRQDDACVDVDECAAEPPP 237
Query 688 QQQP 691
+
Sbjct 238 CEDT 241
Score = 35.9 bits (81), Expect = 1.5, Method: Composition-based stats.
Identities = 21/124 (17%), Positives = 37/124 (30%), Gaps = 6/124 (5%)
Query 574 APEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDV 633
A E P + C+ + S C C+ C A ++ + D
Sbjct 232 AAEPPPCED-TQYCENVNGSFVCEECDPTCMGCTGKGPTQCRECIAGYSKESGQCEDIDE 290
Query 634 ETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPR 693
++ C + +C G C+ CP + E TC + + E+
Sbjct 291 CSLAEKPCLRDNENCYNTPGSF--VCV-CPDG--FEEAEDTCVQTRPAGAEATEASPTQP 345
Query 694 LPPE 697
E
Sbjct 346 PSRE 349
>sp|O23357|SBT42_ARATH Subtilisin-like protease SBT4.2 OS=Arabidopsis
thaliana OX=3702 GN=SBT4.2 PE=3 SV=3
Length=725
Score = 43.3 bits (100), Expect = 0.010, Method: Composition-based stats.
Identities = 23/128 (18%), Positives = 48/128 (38%), Gaps = 16/128 (13%)
Query 316 SISSATQFGNVPWYSEACSSTLATTYS-SGNQNEKQIVTTD---LRQKCTESH--TGTSA 369
+ + + G +S+ S+ + + +Q I TT + + + + TGTS
Sbjct 460 VVPAFSSRGPNTLFSDILSNEHSKRNNRPMSQYISSIFTTGSNRVPGQSVDYYFMTGTSM 519
Query 370 SAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHS-YGYGL 428
+ P AG+ A + + ++ ++ T+ WA N + YG G
Sbjct 520 ACPHVAGVAAYVKTLRPDWSASAIKSAIMTTA---------WAMNASKNAEAEFAYGSGF 570
Query 429 LDAGAMVA 436
++ V
Sbjct 571 VNPTVAVD 578
Score = 42.1 bits (97), Expect = 0.025, Method: Composition-based stats.
Identities = 33/178 (19%), Positives = 53/178 (30%), Gaps = 35/178 (20%)
Query 145 HGIVVSILDDGIEKNHPDL------------AGNYDPGASFDVNDQ--DPDPQPRYTQMN 190
++V ++D GI G G +F N + + +
Sbjct 134 SNVIVGVIDGGIWPESKSFSDEGIGPIPKKWKGTCAGGTNFTCNRKVIGARHYVHDSARD 193
Query 191 DNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGV---RM--------LDGEVTDAVEARS 239
+ HG+ A A GV GVA GGV R+ L + A
Sbjct 194 SDAHGSHTASTAAGNKVKGVSVNGVAEGTARGGVPLGRIAVYKVCEPLGCNGERILAAFD 253
Query 240 LGLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGG 297
+ + + + + S G +D A + A G + A GN G
Sbjct 254 DAIA-DGVDVLTISLGGGVTKVDIDPIAIGSFHAMT---------KGIVTTVAVGNAG 301
>sp|Q04721|NOTC2_HUMAN Neurogenic locus notch homolog protein
2 OS=Homo sapiens OX=9606 GN=NOTCH2 PE=1 SV=3
Length=2471
Score = 43.3 bits (100), Expect = 0.011, Method: Composition-based stats.
Identities = 38/167 (23%), Positives = 51/167 (31%), Gaps = 29/167 (17%)
Query 579 PVPPESS-GCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST-ENDVETI 636
P E S C LT+ CV H ++ V CP L+ +++
Sbjct 1272 PCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQ---MPCLNGGTCAVASNMPDG 1328
Query 637 RASVCAP------CHASCATCQGPALTDCLS--------CPSHASLDPVEQTCSRQ-SQS 681
C P C +SC + C+ CPS E C+ Q
Sbjct 1329 FICRCPPGFSGARCQSSCGQVKCRKGEQCVHTASGPRCFCPSP---RDCESGCASSPCQH 1385
Query 682 SRESPPQQQPPRL-----PPEVEAGQRLRAGLLPSHLPEVVAGLSCA 723
PQ+QPP PP + L PS P CA
Sbjct 1386 GGSCHPQRQPPYYSCQCAPPFSGSRCELYTAP-PSTPPATCLSQYCA 1431
>sp|Q2TJ95|RSPO3_MOUSE R-spondin-3 OS=Mus musculus OX=10090 GN=Rspo3
PE=1 SV=2
Length=277
Score = 42.1 bits (97), Expect = 0.011, Method: Composition-based stats.
Identities = 31/162 (19%), Positives = 45/162 (28%), Gaps = 32/162 (20%)
Query 571 YGTA-PEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
YGT P+ C T + C C+ GF LH C+ CP G +
Sbjct 85 YGTRYPDINKCTKCKVDCDTCFNKNFCTKCKSGFYLHLGKCLDSCPEGLEANNHTMECVS 144
Query 630 ENDVETIRASVCAPCHASCATC-----QGPALTDCLS--------CPSHASLDPV---EQ 673
E S +PC TC + D L CP + +
Sbjct 145 IVHCEASEWSPWSPCMKKGKTCGFKRGTETRVRDILQHPSAKGNLCPPTSETRTCIVQRK 204
Query 674 TCSR---------------QSQSSRESPPQQQPPRLPPEVEA 700
CS+ + +E+ L +E
Sbjct 205 KCSKGERGKKGRERKRKKLNKEERKETSSSSDSKGLESSIET 246
>sp|Q61527|ERBB4_MOUSE Receptor tyrosine-protein kinase erbB-4
OS=Mus musculus OX=10090 GN=Erbb4 PE=1 SV=5
Length=1308
Score = 43.3 bits (100), Expect = 0.012, Method: Composition-based stats.
Identities = 22/92 (24%), Positives = 30/92 (33%), Gaps = 12/92 (13%)
Query 586 GCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCH 645
C +CV+ CP G + D E C PCH
Sbjct 568 TCHGPGPDNCTKCSH---FKDGPNCVEKCPDGLQGANSFIFKYADQDRE------CHPCH 618
Query 646 ASCAT-CQGPALTDCLSCP--SHASLDPVEQT 674
+C C GP DC+ P H++L +T
Sbjct 619 PNCTQGCNGPTSHDCIYYPWTGHSTLPQHART 650
Score = 41.7 bits (96), Expect = 0.035, Method: Composition-based stats.
Identities = 22/132 (17%), Positives = 34/132 (26%), Gaps = 31/132 (23%)
Query 551 IENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSC 610
I + S Y T+ +T L+ T + + + C
Sbjct 460 ITDNSNLCYYHTI-NWT-TLFSTINQRIVIRDNRRAENCTAEGMVCNHL---------CS 508
Query 611 VQHCPPGFAPQVLDTHYSTENDV-------------ETIRASVCAPCHASCA-------T 650
C Q L + + E S+C C + C T
Sbjct 509 NDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFENGSICVECDSQCEKMEDGLLT 568
Query 651 CQGPALTDCLSC 662
C GP +C C
Sbjct 569 CHGPGPDNCTKC 580
Score = 39.8 bits (91), Expect = 0.12, Method: Composition-based stats.
Identities = 22/97 (23%), Positives = 29/97 (30%), Gaps = 19/97 (20%)
Query 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP--------------CHA 646
+L + C TEN +T+ +VCA CH
Sbjct 173 SNMTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHR 232
Query 647 SCAT-CQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
CA C GP TDC +C C Q +
Sbjct 233 ECAGGCSGPKDTDCFAC----MNFNDSGACVTQCPQT 265
>sp|Q7SXF6|CREL2_DANRE Cysteine-rich with EGF-like domain protein
2 OS=Danio rerio OX=7955 GN=creld2 PE=2 SV=2
Length=341
Score = 42.5 bits (98), Expect = 0.013, Method: Composition-based stats.
Identities = 21/113 (19%), Positives = 35/113 (31%), Gaps = 7/113 (6%)
Query 582 PESSGCKTLTSSQA---CVVCEEGFSLHQKSCVQHCPPGFAPQ-VLDTHYSTENDVETIR 637
P+ + C +G C C G+ + LD N +
Sbjct 135 PDCNTCIGGADRPCHGNGKCDGDGTRAGNGKC--SCDEGYDGEFCLDCSDGYFNSLRNDT 192
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQ 690
+C CH SC C G C C + + E +C ++ ++ P
Sbjct 193 FFLCKECHESCVGCSGGTNQHCKECR-NGWVKDQEGSCIDINECIKDPAPCSD 244
Score = 36.3 bits (82), Expect = 0.99, Method: Composition-based stats.
Identities = 23/99 (23%), Positives = 33/99 (33%), Gaps = 13/99 (13%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVE---------TIR 637
CK S CV C G + H K C +D + ++ T
Sbjct 196 CKECHES--CVGCSGGTNQHCKECRNGWVKDQEGSCIDINECIKDPAPCSDDQYCLNTDG 253
Query 638 ASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCS 676
+ C C C C+G + CL+C E TC+
Sbjct 254 SFSCKACDIRCTGCKGDGASSCLNC--ADGYKDEEGTCT 290
>sp|O73559|CRMB_CWPXG Soluble TNF receptor II OS=Cowpox virus
(strain GRI-90 / Grishak) OX=265871 GN=OPG002 PE=3 SV=1
Length=351
Score = 42.1 bits (97), Expect = 0.014, Method: Composition-based stats.
Identities = 21/92 (23%), Positives = 34/92 (37%), Gaps = 8/92 (9%)
Query 590 LTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCA 649
+ + ++ H C+ CPPG T+ S D +T + C PC +
Sbjct 24 PHAPSNGKCKDNEYNRHNLCCLS-CPPG-------TYASRLCDSKTNTNTQCTPCGSGTF 75
Query 650 TCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
T + L CLSC + VE + +
Sbjct 76 TSRNNHLPACLSCNGRCDSNQVETRSCNTTHN 107
>sp|Q28295|VWF_CANLF von Willebrand factor OS=Canis lupus familiaris
OX=9615 GN=VWF PE=1 SV=2
Length=2813
Score = 42.9 bits (99), Expect = 0.014, Method: Composition-based stats.
Identities = 41/249 (16%), Positives = 73/249 (29%), Gaps = 30/249 (12%)
Query 452 IDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRR-GDL-AIHLVSPM 509
I++ + + +++ TV L ++ T+ Y R L I +P
Sbjct 2005 IEVKHDGLSVELHSDMQMTVNGRLVSIPYVGGDMEVNVYGTIMYEVRFNHLGHIFTFTPQ 2064
Query 510 GTRSTL-LAARPHDYSADGFNDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTL 568
L L+ R G DE+ + +++L + T + + ++T+
Sbjct 2065 NNEFQLQLSPRTFASKTYGLCGIC-------DENGANDFILR-DGTVTTDWKALIQEWTV 2116
Query 569 VLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGF-----SLHQKSCVQHCPPGFAPQVL 623
G + +P C +SS V+ E F L + C P
Sbjct 2117 QQLGKTCQPVP----EEQCPVSSSSHCQVLLSELFAECHKVLAPATFYAMCQPDSCHPKK 2172
Query 624 DTHYSTENDVETIRASVCAPCHASCATCQGPALTDC-LSCPSHASLDPVEQTCSRQSQSS 682
VC C +SCP + E C R + +
Sbjct 2173 VCEAIALYAHLCRTKGVCVD---------WRRANFCAMSCPPSLVYNHCEHGCPRLCEGN 2223
Query 683 RESPPQQQP 691
S Q
Sbjct 2224 TSSCGDQPS 2232
>sp|Q15303|ERBB4_HUMAN Receptor tyrosine-protein kinase erbB-4
OS=Homo sapiens OX=9606 GN=ERBB4 PE=1 SV=1
Length=1308
Score = 42.9 bits (99), Expect = 0.016, Method: Composition-based stats.
Identities = 23/103 (22%), Positives = 33/103 (32%), Gaps = 12/103 (12%)
Query 575 PEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
P+ + C +CV+ CP G + D E
Sbjct 557 PQCEKMEDGLLTCHGPGPDNCTKCSH---FKDGPNCVEKCPDGLQGANSFIFKYADPDRE 613
Query 635 TIRASVCAPCHASCAT-CQGPALTDCLSCP--SHASLDPVEQT 674
C PCH +C C GP DC+ P H++L +T
Sbjct 614 ------CHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHART 650
Score = 41.3 bits (95), Expect = 0.041, Method: Composition-based stats.
Identities = 22/132 (17%), Positives = 33/132 (25%), Gaps = 31/132 (23%)
Query 551 IENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSC 610
I + S Y T+ +T L+ T + + + C
Sbjct 460 ITDNSNLCYYHTI-NWT-TLFSTINQRIVIRDNRKAENCTAEGMVCNHL---------CS 508
Query 611 VQHCPPGFAPQVLDTHYSTENDV-------------ETIRASVCAPCHASCA-------T 650
C Q L + + E S+C C C T
Sbjct 509 SDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLT 568
Query 651 CQGPALTDCLSC 662
C GP +C C
Sbjct 569 CHGPGPDNCTKC 580
Score = 39.8 bits (91), Expect = 0.12, Method: Composition-based stats.
Identities = 22/94 (23%), Positives = 29/94 (31%), Gaps = 19/94 (20%)
Query 604 SLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP--------------CHASCA 649
+L + C TEN +T+ +VCA CH CA
Sbjct 176 TLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECA 235
Query 650 T-CQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
C GP TDC +C C Q +
Sbjct 236 GGCSGPKDTDCFAC----MNFNDSGACVTQCPQT 265
>sp|Q5M7L6|RSPO2_XENTR R-spondin-2 OS=Xenopus tropicalis OX=8364
GN=rspo2 PE=1 SV=1
Length=243
Score = 41.3 bits (95), Expect = 0.016, Method: Composition-based stats.
Identities = 25/121 (21%), Positives = 40/121 (33%), Gaps = 32/121 (26%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQACVVCE--EGFSLHQK------SCVQHCPPGFAPQV 622
YGT P GC + + C+ C+ F L ++ C+Q CPPG+
Sbjct 34 YGT-------NPICKGCLSCSKDNGCLRCQPKLFFYLRREGMRQYGECLQSCPPGYYG-- 84
Query 623 LDTHYSTENDVETIRASVCAPCH-ASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
V + C+ C +C +C C+ C S + C +
Sbjct 85 ----------VRGPDMNRCSRCRIENCDSCFSR--DFCIKCKSGFYSH--KGQCFEECPE 130
Query 682 S 682
Sbjct 131 G 131
>sp|Q5UQ50|COLL6_MIMIV Collagen-like protein 6 OS=Acanthamoeba
polyphaga mimivirus OX=212035 GN=MIMI_L668 PE=4 SV=1
Length=1387
Score = 42.5 bits (98), Expect = 0.017, Method: Composition-based stats.
Identities = 68/382 (18%), Positives = 123/382 (32%), Gaps = 74/382 (19%)
Query 190 NDNRHGTRCAGEVAAVANNGVCGVGV-AYNARIGGVRMLDGEV---TDAVEARSLGLNPN 245
+DN HG++ +G V NNG +G ++ + + G + T++ + +GL N
Sbjct 975 SDNVHGSQISGIV---TNNGQMTIGTLSHGSYLHGYADTSSTISIGTNSFGSECIGLAQN 1031
Query 246 HIHIYSA--SWGPEDDGKTVDGPARLAEE------------------------------- 272
+ I + S+G G T+ G
Sbjct 1032 NGTINNGDLSFGCRISGWTLSGLLSTGSGSCGTILYGVAVNSGIINTSGRNFGCFVGGYC 1091
Query 273 AFFRGVSQGRGGLGSI---FVWASGNGGREHDSCNCDGYTNSIYTLSISSATQFGNVPWY 329
A++ ++ G G+I ASG +S +S T+S+ S + Y
Sbjct 1092 AYYGKITIGANSFGTICHGTADASGTILVGTNSTGNLVVGSSQGTISLGSTNFGSVILGY 1151
Query 330 SEACSSTLATTYSSGNQNEKQIVTTDLRQKCTESHT-----GTSASAPLAAGIIALTLEA 384
+E S ++ + G + L T GTS SA +G+ + T
Sbjct 1152 TENSGSIISDGNNRGIFMHGYSSSASLYTASGSCGTVLMGYGTSGSAINVSGLGSFTFGY 1211
Query 385 NKNLTWRDMQHLVVQTSKPAHLNANDWATNGVGRKVSHSYGYGLLDAGAMVALAQNWTTV 444
+ ++ ++ S N + N S S GYG A + + + +++
Sbjct 1212 CP--SSGEITQVLANGSFAFGRNNTTVSEN------SFSLGYG---ARSYMPGSMAFSSF 1260
Query 445 APQRKC-IIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHAQARLTLSYNRRGDLAI 503
A K + + L + TL Y G++
Sbjct 1261 ATSGNPLRAGSAQTIKVLTRNLNTEFVLADGNFP--------------TLPYTGYGNIKA 1306
Query 504 HLVSPMGTRSTLLAARPHDYSA 525
++ GT S L D S
Sbjct 1307 KIIGSSGTMSVLYFQVFFDGST 1328
>sp|Q5EA46|CREL1_BOVIN Protein disulfide isomerase CRELD1 OS=Bos
taurus OX=9913 GN=CRELD1 PE=2 SV=1
Length=420
Score = 42.1 bits (97), Expect = 0.018, Method: Composition-based stats.
Identities = 20/102 (20%), Positives = 35/102 (34%), Gaps = 12/102 (12%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP 643
C+ + C+ ++C Q C G+ + + VC+
Sbjct 166 YGHCEGEGTRGGSGHCDCQAGYGGEACGQ-CGLGYFEAERNASHL-----------VCSA 213
Query 644 CHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRES 685
C CA C GP + CL C +L ++ + + R S
Sbjct 214 CFGPCARCSGPEESHCLQCKKGWALHHLKCVDIDECGTERAS 255
Score = 41.3 bits (95), Expect = 0.034, Method: Composition-based stats.
Identities = 23/116 (20%), Positives = 38/116 (33%), Gaps = 20/116 (17%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQ--HCPPGFAPQVLDTHYSTENDVETIRASVC 641
+ C S C+ C++G++LH CV C + + + V T + C
Sbjct 218 CARCSGPEESH-CLQCKKGWALHHLKCVDIDEC-----GTERASCGADQFCVNTEGSYEC 271
Query 642 APCHASCATCQGPALTDCLSCPSHAS--------LDPVEQTCSR----QSQSSRES 685
C +C C G C C +D E Q +++ S
Sbjct 272 RDCAKACLGCMGAGPGRCKKCSPGYQQVGSKCLDVDECETAVCPGENQQCENTEGS 327
>sp|Q2MKA7|RSPO1_HUMAN R-spondin-1 OS=Homo sapiens OX=9606 GN=RSPO1
PE=1 SV=1
Length=263
Score = 41.3 bits (95), Expect = 0.018, Method: Composition-based stats.
Identities = 22/127 (17%), Positives = 37/127 (29%), Gaps = 25/127 (20%)
Query 585 SGCKTLTSSQACVVCE-EGFSLHQKS-------CVQHCPPGFAPQVLDTHYSTENDVETI 636
GC+ + C+ C + F L +++ C+ CPPG+ D
Sbjct 42 KGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYF------------DARNP 89
Query 637 RASVCAPCH-ASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLP 695
+ C C C C + C C L + C + P
Sbjct 90 DMNKCIKCKIEHCEACF--SHNFCTKCKEGLYLH--KGRCYPACPEGSSAANGTMECSSP 145
Query 696 PEVEAGQ 702
+ E +
Sbjct 146 AQCEMSE 152
>sp|O35516|NOTC2_MOUSE Neurogenic locus notch homolog protein
2 OS=Mus musculus OX=10090 GN=Notch2 PE=1 SV=2
Length=2473
Score = 42.5 bits (98), Expect = 0.018, Method: Composition-based stats.
Identities = 28/130 (22%), Positives = 44/130 (34%), Gaps = 17/130 (13%)
Query 579 PVPPESS-GCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST-ENDVETI 636
P E S C L ++ C+ H ++ + CP L+ +++
Sbjct 1272 PCSSEGSLDCVQLKNNYNCICRSAFTGRHCETFLDVCPQ---KPCLNGGTCAVASNMPDG 1328
Query 637 RASVCAP------CHASCATCQGPALTDCL---SCPSHASLDP--VEQTCSRQ-SQSSRE 684
C P C +SC + C+ S P L+P E C+ Q
Sbjct 1329 FICRCPPGFSGARCQSSCGQVKCRRGEQCIHTDSGPRCFCLNPKDCESGCASNPCQHGGT 1388
Query 685 SPPQQQPPRL 694
PQ+QPP
Sbjct 1389 CYPQRQPPHY 1398
>sp|O18735|ERBB2_CANLF Receptor tyrosine-protein kinase erbB-2
OS=Canis lupus familiaris OX=9615 GN=ERBB2 PE=2 SV=1
Length=1259
Score = 42.5 bits (98), Expect = 0.019, Method: Composition-based stats.
Identities = 25/129 (19%), Positives = 37/129 (29%), Gaps = 30/129 (23%)
Query 567 TLVLYGTAPEGLPVPPESSGCKTLTSSQA-------CVVCEEGFSLHQKSCVQHCPPGFA 619
+L+ E C CV C + L + CV+ C
Sbjct 491 QALLHSANRPEEECVGEGLACYPCAHGHCWGPGPTQCVNCSQ--FLRGQECVEECRVLQG 548
Query 620 PQVLDTHYSTENDVETIRASVCAPCHASCA------TCQGPALTDCLSCPSHASLDPVEQ 673
E ++ C PCH+ C TC G C++C +H P
Sbjct 549 LP-----------REYVKDRYCLPCHSECQPQNGSVTCFGSEADQCVAC-AHYKDPPF-- 594
Query 674 TCSRQSQSS 682
C + S
Sbjct 595 -CVARCPSG 602
>sp|Q5UE90|RSPO2_XENLA R-spondin-2 OS=Xenopus laevis OX=8355 GN=rspo2
PE=2 SV=1
Length=243
Score = 41.3 bits (95), Expect = 0.020, Method: Composition-based stats.
Identities = 23/121 (19%), Positives = 41/121 (34%), Gaps = 32/121 (26%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQACVVCE-EGFSLHQKS-------CVQHCPPGFAPQV 622
YGT P GC + + C+ C+ + F ++ C+Q CPPG+
Sbjct 34 YGT-------NPICKGCLSCSKDNGCLRCQPKLFFFLRREGMRQYGECLQSCPPGYYG-- 84
Query 623 LDTHYSTENDVETIRASVCAPCH-ASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
V + C+ C +C +C C+ C + ++ C +
Sbjct 85 ----------VRGPDMNRCSRCRIENCDSCFSR--DFCIKC--KSGFYSLKGQCFEECPE 130
Query 682 S 682
Sbjct 131 G 131
>sp|P13387|EGFR_CHICK Epidermal growth factor receptor (Fragment)
OS=Gallus gallus OX=9031 GN=EGFR PE=1 SV=1
Length=703
Score = 42.1 bits (97), Expect = 0.021, Method: Composition-based stats.
Identities = 39/222 (18%), Positives = 60/222 (27%), Gaps = 61/222 (27%)
Query 583 ESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEND---------- 632
+S K + + + C + +
Sbjct 491 QSQKTKIIQNRNKNDCTADRHVCDPLCSDVGCWGPGPFHCFSCRFFSRQKECVKQCNILQ 550
Query 633 ---VETIRASVCAPCHASCA---------TCQGPALTDCL-------------SCPSH-- 665
E R S C PCH+ C TC GP C+ +CP+
Sbjct 551 GEPREFERDSKCLPCHSECLVQNSTAYNTTCSGPGPDHCMKCAHFIDGPHCVKACPAGVL 610
Query 666 ----------ASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPE 715
A + V Q C + P + P PS
Sbjct 611 GENDTLVWKYADANAVCQLCHPNCTRGCKGPGLEGCP------------NGSKTPSIAAG 658
Query 716 VVAGLSCAFIVLVFVTVFLVLQLRSGFSFRGVKVYTMDRGLI 757
VV GL C V+V + + L L+ R R ++ +R L+
Sbjct 659 VVGGLLCL--VVVGLGIGLYLRRRHIVRKRTLRRLLQERELV 698
Score = 38.6 bits (88), Expect = 0.26, Method: Composition-based stats.
Identities = 21/102 (21%), Positives = 26/102 (25%), Gaps = 4/102 (4%)
Query 580 VPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRAS 639
+ K LT H HC + R
Sbjct 172 NDIIDTSRKPLTVLDFASNLSSCPKCHPNCTEDHCWGAGEQNCQTLTKVICAQQCSGRCR 231
Query 640 VCAP---CHASCAT-CQGPALTDCLSCPSHASLDPVEQTCSR 677
P CH CA C GP +DCL+C + TC
Sbjct 232 GKVPSDCCHNQCAAGCTGPRESDCLACRKFRDDATCKDTCPP 273
>sp|Q5UNS9|COLL7_MIMIV Collagen-like protein 7 OS=Acanthamoeba
polyphaga mimivirus OX=212035 GN=MIMI_L669 PE=4 SV=1
Length=1937
Score = 42.1 bits (97), Expect = 0.024, Method: Composition-based stats.
Identities = 45/215 (21%), Positives = 76/215 (35%), Gaps = 34/215 (16%)
Query 208 NGVCGVGV---AYNARIGGVRMLDGEVT----DAVEARSLGLNPNHIHIYSAS------- 253
N +G+ A+ + G L+ +T A R +G N+ I+ S
Sbjct 1575 NRGSTLGINQNAFGYSVMGYADLNSTITSNALGANACRIMGYALNNSTIFMDSLVAANAT 1634
Query 254 --WGPEDDGKTVDGPARLAEEAFFRGVSQG-----RGGLGSIFVWASGNG-----GREHD 301
+G ++ + + A A RGV+Q G GS+ S N G+ D
Sbjct 1635 DLFGYANNSGVIQAADQCAG-ALARGVAQNNSSIVTRGNGSMTFGFSNNNSTIFTGQFSD 1693
Query 302 SCNCDGYTNSIYTLSISSATQFGNVPWYSEACS-------STLATTYSSGNQNEKQIVTT 354
C GY NS T+S S + +V +S + S + +T + N
Sbjct 1694 GCFVGGYANSGGTISTGSTSPASHVFGFSNSGSFITTGNNTNASTVFGYATANSTITTGA 1753
Query 355 DLRQKCTESHTGTSASAPLAAGIIALTLEANKNLT 389
+ +TG+S A G + + N +
Sbjct 1754 NSNGSLAVGYTGSSGELLGALGQTSFAIGRNNTAS 1788
>sp|Q62956|ERBB4_RAT Receptor tyrosine-protein kinase erbB-4 OS=Rattus
norvegicus OX=10116 GN=Erbb4 PE=1 SV=3
Length=1308
Score = 42.1 bits (97), Expect = 0.024, Method: Composition-based stats.
Identities = 22/132 (17%), Positives = 34/132 (26%), Gaps = 31/132 (23%)
Query 551 IENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSC 610
I + S Y T+ +T L+ T + + + C
Sbjct 460 ITDNSNLCYYHTI-NWT-TLFSTVNQRIVIRDNRRAENCTAEGMVCNHL---------CS 508
Query 611 VQHCPPGFAPQVLDTHYSTENDV-------------ETIRASVCAPCHASCA-------T 650
C Q L + + E S+C C + C T
Sbjct 509 NDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFENGSICVECDSQCEKMEDGLLT 568
Query 651 CQGPALTDCLSC 662
C GP +C C
Sbjct 569 CHGPGPDNCTKC 580
Score = 40.2 bits (92), Expect = 0.085, Method: Composition-based stats.
Identities = 21/92 (23%), Positives = 29/92 (32%), Gaps = 12/92 (13%)
Query 586 GCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCH 645
C +CV+ CP + D E C PCH
Sbjct 568 TCHGPGPDNCTKCSH---FKDGPNCVEKCPDVLQGANSFIFKYADQDRE------CHPCH 618
Query 646 ASCAT-CQGPALTDCLSCP--SHASLDPVEQT 674
+C C GP DC+ P H++L +T
Sbjct 619 PNCTQGCNGPTSHDCIYYPWTGHSTLPQHART 650
Score = 39.4 bits (90), Expect = 0.17, Method: Composition-based stats.
Identities = 22/97 (23%), Positives = 28/97 (29%), Gaps = 19/97 (20%)
Query 601 EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP--------------CHA 646
+L C TEN +T+ +VCA CH
Sbjct 173 SNMTLVSTIGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHR 232
Query 647 SCAT-CQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
CA C GP TDC +C C Q +
Sbjct 233 ECAGGCSGPKDTDCFAC----MNFNDSGACVTQCPQT 265
>sp|P42790|PICP_PSESR Pseudomonalisin OS=Pseudomonas sp. (strain
101) OX=33067 GN=pcp PE=1 SV=1
Length=587
Score = 41.7 bits (96), Expect = 0.029, Method: Composition-based stats.
Identities = 55/296 (19%), Positives = 89/296 (30%), Gaps = 64/296 (22%)
Query 143 TGHGIVVSILD-DGIEKNHPDLAGNYDPGASFDVNDQDPDPQPRYTQMNDNRHGTRCAGE 201
T V I+ G+ + DL VN Q +D++ G GE
Sbjct 239 TAANTTVGIITIGGVSQTLQDLQQFTSANGLASVNTQTIQTGSSNGDYSDDQQG---QGE 295
Query 202 VAAVANNGVCGVGVAYNA-RIGGVRMLDGEV---TDAVEARSLGLNPNHIHIYSASWGPE 257
+ VG A A + M D T +A + ++ N + + S G
Sbjct 296 ---WDLDSQSIVGSAGGAVQQLLFYMADQSASGNTGLTQAFNQAVSDNVAKVINVSLGWC 352
Query 258 DDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREHDSCNCDGY--------- 308
+ DG + + F +Q G F +SG+ G CN GY
Sbjct 353 EADANADGTLQAEDRIFATAAAQ-----GQTFSVSSGDEGVYE--CNNRGYPDGSTYSVS 405
Query 309 --TNSIYTLSISSATQFGNVP-WYSEA--------CSSTLATTYSSGNQNEKQI------ 351
+S +++ T + YS + L T + E +
Sbjct 406 WPASSPNVIAVGGTTLYTTSAGAYSNETVWNEGLDSNGKLWATGGGYSVYESKPSWQSVV 465
Query 352 -----------VTTDLRQKCTE---------SHTGTSASAPLAAGIIALTLEANKN 387
++ D Q GTS ++P+ G+ A AN N
Sbjct 466 SGTPGRRLLPDISFDAAQGTGALIYNYGQLQQIGGTSLASPIFVGLWARLQSANSN 521
>sp|Q07627|KRA11_HUMAN Keratin-associated protein 1-1 OS=Homo
sapiens OX=9606 GN=KRTAP1-1 PE=1 SV=1
Length=177
Score = 39.8 bits (91), Expect = 0.033, Method: Composition-based stats.
Identities = 19/80 (24%), Positives = 25/80 (31%), Gaps = 2/80 (3%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVC 641
P S T SS C E S + C C Q + + + T +S C
Sbjct 12 PSCSTSGTCGSSCCQPSCCETSSCQPRCCETSCCQPSCCQTSFCGFPSFSTGGTCDSSCC 71
Query 642 AP--CHASCATCQGPALTDC 659
P C SC + C
Sbjct 72 QPSCCETSCCQPSCYQTSSC 91
>sp|Q8CJ69|BMPER_MOUSE BMP-binding endothelial regulator protein
OS=Mus musculus OX=10090 GN=Bmper PE=1 SV=1
Length=685
Score = 41.3 bits (95), Expect = 0.034, Method: Composition-based stats.
Identities = 31/138 (22%), Positives = 45/138 (33%), Gaps = 24/138 (17%)
Query 554 TSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQH 613
T E Y + K+ T E + G T + + V C + + HQ +C
Sbjct 109 THEGRTYNSSFKWQ-----TPAEPCVLRQCQEGVVTESEVRCVVHC-KNPAEHQGACCPT 162
Query 614 CPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDC-------LSCPSHA 666
CP + E + + C C +C G T C LSCP H
Sbjct 163 CPGCVF----EGVQYREGEEFQPEGNKCITC-----SCVGGR-TQCVREVCPILSCPQHL 212
Query 667 SLDPVEQTCSRQSQSSRE 684
S P C + R+
Sbjct 213 SHTP-SGQCCPKCLGQRK 229
>sp|Q9QW30|NOTC2_RAT Neurogenic locus notch homolog protein 2
OS=Rattus norvegicus OX=10116 GN=Notch2 PE=1 SV=1
Length=2471
Score = 41.7 bits (96), Expect = 0.036, Method: Composition-based stats.
Identities = 29/133 (22%), Positives = 43/133 (32%), Gaps = 23/133 (17%)
Query 579 PVPPESS-GCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST-ENDVETI 636
P E S C L ++ CV H ++ + CP L+ ++V
Sbjct 1272 PCSSEGSLDCIQLKNNYQCVCRSAFTGRHCETFLDVCPQ---KPCLNGGTCAVASNVPDG 1328
Query 637 RASVCAP------CHASCATCQGPALTDCLS--------CPSHASLDPVEQTCSRQ-SQS 681
C P C +SC + C+ CP+H E C+ Q
Sbjct 1329 FICRCPPGFSGARCQSSCGQVKCRRGEQCVHTASGPHCFCPNH---KDCESGCASNPCQH 1385
Query 682 SRESPPQQQPPRL 694
PQ+QPP
Sbjct 1386 GGTCYPQRQPPYY 1398
>sp|F1LWT0|SIMC1_RAT SUMO-interacting motif-containing protein
1 OS=Rattus norvegicus OX=10116 GN=Simc1 PE=3 SV=3
Length=1266
Score = 41.7 bits (96), Expect = 0.036, Method: Composition-based stats.
Identities = 22/105 (21%), Positives = 32/105 (30%), Gaps = 13/105 (12%)
Query 613 HCPPGFAPQVLDTHYSTENDV-ETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPV 671
CP P + + +R S C P +SC LSCP A
Sbjct 203 PCPQQDVPCQSQGLLCSLQALSYPLRGSPCPPRASSC-------PPQALSCPPQALSSL- 254
Query 672 EQTCSRQSQSSRESPPQQQPPRLPPEVEAG--QRLRAGLLPSHLP 714
+C Q+ + Q P +P + + P LP
Sbjct 255 --SCPSQTVQCQLQALPQPPQEVPCSTQNVPCPQQNIPSTPQDLP 297
>sp|Q4V7F2|CREL1_RAT Protein disulfide isomerase Creld1 OS=Rattus
norvegicus OX=10116 GN=Creld1 PE=2 SV=1
Length=420
Score = 41.0 bits (94), Expect = 0.038, Method: Composition-based stats.
Identities = 18/86 (21%), Positives = 32/86 (37%), Gaps = 12/86 (14%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C+ + C+ ++C Q C G+ ++ + VC+ C
Sbjct 169 CEGEGTRGGSGHCDCQAGYGGEACGQ-CGLGYFEAERNSSHL-----------VCSACFG 216
Query 647 SCATCQGPALTDCLSCPSHASLDPVE 672
CA C GP + CL C +L ++
Sbjct 217 PCARCTGPEESHCLQCRKGWALHHLK 242
Score = 39.8 bits (91), Expect = 0.093, Method: Composition-based stats.
Identities = 22/94 (23%), Positives = 31/94 (33%), Gaps = 10/94 (11%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQ--HCPPGFAPQVLDTHYSTENDVETIRASVC 641
+ C S C+ C +G++LH CV C T + + V T + C
Sbjct 218 CARCTGPEESH-CLQCRKGWALHHLKCVDIDEC-----GTEQATCGAAQFCVNTEGSYEC 271
Query 642 APCHASCATCQGPALTDCLSCPSHASLDPVEQTC 675
C +C C G C C V C
Sbjct 272 RDCAKACLGCMGAGPGRCKKC--SRGYQQVGSKC 303
>sp|Q91XD7|CREL1_MOUSE Protein disulfide isomerase Creld1 OS=Mus
musculus OX=10090 GN=Creld1 PE=1 SV=1
Length=420
Score = 41.0 bits (94), Expect = 0.040, Method: Composition-based stats.
Identities = 18/86 (21%), Positives = 32/86 (37%), Gaps = 12/86 (14%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C+ + C+ ++C Q C G+ ++ + VC+ C
Sbjct 169 CEGEGTRGGSGHCDCQAGYGGEACGQ-CGLGYFEAERNSSHL-----------VCSACFG 216
Query 647 SCATCQGPALTDCLSCPSHASLDPVE 672
CA C GP + CL C +L ++
Sbjct 217 PCARCTGPEESHCLQCKKGWALHHLK 242
Score = 40.2 bits (92), Expect = 0.071, Method: Composition-based stats.
Identities = 22/94 (23%), Positives = 32/94 (34%), Gaps = 10/94 (11%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQ--HCPPGFAPQVLDTHYSTENDVETIRASVC 641
+ C S C+ C++G++LH CV C T + + V T + C
Sbjct 218 CARCTGPEESH-CLQCKKGWALHHLKCVDIDEC-----GTEQATCGADQFCVNTEGSYEC 271
Query 642 APCHASCATCQGPALTDCLSCPSHASLDPVEQTC 675
C +C C G C C V C
Sbjct 272 RDCAKACLGCMGAGPGRCKKC--SRGYQQVGSKC 303
>sp|Q8BJ73|RSPO4_MOUSE R-spondin-4 OS=Mus musculus OX=10090 GN=Rspo4
PE=1 SV=2
Length=228
Score = 40.2 bits (92), Expect = 0.047, Method: Composition-based stats.
Identities = 27/137 (20%), Positives = 45/137 (33%), Gaps = 5/137 (4%)
Query 558 NNYGT-LTKFTLVLYGT-APEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCP 615
YG + L +G E + C++ S C+ C+ F L++ C+ CP
Sbjct 64 RQYGKCVHDCPLGFFGIRGQEANRCKKCGATCESCFSQDFCIRCKRRFHLYKGKCLPSCP 123
Query 616 PGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTC 675
PG + + E +PC + TC + E
Sbjct 124 PGTLTHQSTRE--CQEECEPSPWGSWSPCIHNGKTCGSGWGLE-TRVREAGPAKQEETAS 180
Query 676 SRQSQSSRESPPQQQPP 692
R SR+ P ++ P
Sbjct 181 CRVLSESRKCPIKRLCP 197
>sp|P85156|ASE1_ACRSP Subtilisin-like serine protease AS-E1 (Fragment)
OS=Acremonium sp. OX=2046025 PE=1 SV=1
Length=40
Score = 35.9 bits (81), Expect = 0.048, Method: Composition-based stats.
Identities = 9/35 (26%), Positives = 14/35 (40%), Gaps = 0/35 (0%)
Query 122 WYLSGVTQRDLNVKAAWAQGYTGHGIVVSILDDGI 156
W L+ ++ R + G G I+D GI
Sbjct 5 WGLARISHRTTGATSYVYDDSAGEGTCSYIIDTGI 39
>sp|Q01279|EGFR_MOUSE Epidermal growth factor receptor OS=Mus
musculus OX=10090 GN=Egfr PE=1 SV=1
Length=1210
Score = 41.0 bits (94), Expect = 0.049, Method: Composition-based stats.
Identities = 19/108 (18%), Positives = 33/108 (31%), Gaps = 11/108 (10%)
Query 565 KFTLVLYGTAPEGLP--VPPESSGCKTLTSSQACVVCEEG-FSLHQKSCVQHCPPGFAPQ 621
+ L+GT + CK + + EG + + CV +
Sbjct 476 NWK-KLFGTPNQKTKIMNNRAEKDCKAVNHVCNPLCSSEGCWGPEPRDCVSCQNVSRGRE 534
Query 622 VLDTHYSTENDVETIRASV-CAPCHASCA------TCQGPALTDCLSC 662
++ E + + C CH C TC G +C+ C
Sbjct 535 CVEKCNILEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQC 582
Score = 36.3 bits (82), Expect = 1.3, Method: Composition-based stats.
Identities = 19/78 (24%), Positives = 25/78 (32%), Gaps = 9/78 (12%)
Query 609 SCVQHCPPG--FAPQVLDTHYSTENDVETIRASVCAP------CHASCAT-CQGPALTDC 659
C CP G + + T+ + C CH CA C GP +DC
Sbjct 189 KCDPSCPNGSCWGGGEENCQKLTKIICAQQCSHRCRGRSPSDCCHNQCAAGCTGPRESDC 248
Query 660 LSCPSHASLDPVEQTCSR 677
L C + TC
Sbjct 249 LVCQKFQDEATCKDTCPP 266
>sp|Q8C3L1|SSUH2_MOUSE Protein SSUH2 homolog OS=Mus musculus OX=10090
GN=Ssuh2 PE=1 SV=1
Length=340
Score = 40.2 bits (92), Expect = 0.066, Method: Composition-based stats.
Identities = 16/106 (15%), Positives = 31/106 (29%), Gaps = 9/106 (8%)
Query 572 GTAPEGLPVPPE-----SSGCKTLTSSQAC--VVCEEGFSLHQKSCVQHCPPGFAPQVLD 624
GT+P + + + L + C + + C C +
Sbjct 144 GTSPRLWDMKVQVPPMFQEDTRKLQVPHSSLVKECHKCHGRGRYKC-SGCHGAGMVRCSS 202
Query 625 THYSTENDVETIRASVCAPC-HASCATCQGPALTDCLSCPSHASLD 669
+ + R +C+ C+TC G C +C L+
Sbjct 203 CSGTKRKAKQPRRCHLCSGSGRRRCSTCSGRGNKTCATCKGERKLE 248
>sp|Q80V70|MEGF6_MOUSE Multiple epidermal growth factor-like domains
protein 6 OS=Mus musculus OX=10090 GN=Megf6 PE=2 SV=3
Length=1572
Score = 40.6 bits (93), Expect = 0.066, Method: Composition-based stats.
Identities = 27/92 (29%), Positives = 30/92 (33%), Gaps = 10/92 (11%)
Query 593 SQACVVCEEGFSLHQKSCVQHCPPGFAPQ-VLDTHYSTENDVETIRASVCAP----CHAS 647
+Q C C G S H S HCPPGF + C CH +
Sbjct 1174 AQRC-HCPPGASCHHVSGECHCPPGFTGPGCEQACQPGTFGKDCEHPCQCPGETWACHPA 1232
Query 648 CATC---QGPALTDCLS-CPSHASLDPVEQTC 675
C G TDC CPS EQ C
Sbjct 1233 SGACVCAAGYHGTDCQQRCPSGRYGPGCEQIC 1264
Score = 36.7 bits (83), Expect = 1.2, Method: Composition-based stats.
Identities = 22/118 (19%), Positives = 31/118 (26%), Gaps = 7/118 (6%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCA---- 642
C L + C G H PG + L T + + C
Sbjct 621 CHRLYGACLCDPGLYGRFCHLACPPWAFGPGCSEDCLCEQSHTRSCNSKDGSCSCKAGFQ 680
Query 643 --PCHASCAT-CQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPE 697
C A C GP + +C + DPV C Q + Q +
Sbjct 681 GERCEAECEPGSFGPGCRNRCTCRPGVACDPVSGECRTQCPPGYQGEDCGQECPVGTF 738
>sp|P55245|EGFR_MACMU Epidermal growth factor receptor OS=Macaca
mulatta OX=9544 GN=EGFR PE=2 SV=2
Length=1210
Score = 40.6 bits (93), Expect = 0.066, Method: Composition-based stats.
Identities = 31/150 (21%), Positives = 49/150 (33%), Gaps = 19/150 (13%)
Query 547 WVLEIENTSEANNYGT----LTKFTLVLYGT---APEGLPVPPESSGCKTLTSSQACVVC 599
+ L + + +AN G + +L+G + ES + + SS+
Sbjct 117 YALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSEFLSNM 176
Query 600 EEGFSLHQ---KSCVQHCPPG--FAPQVLDTHYSTENDVETIRASVCAP------CHASC 648
F H + C CP G + + T+ + C CH C
Sbjct 177 SMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQC 236
Query 649 AT-CQGPALTDCLSCPSHASLDPVEQTCSR 677
A C GP +DCL C + TC
Sbjct 237 AAGCTGPRESDCLVCRKFRDEATCKDTCPP 266
Score = 39.8 bits (91), Expect = 0.12, Method: Composition-based stats.
Identities = 18/117 (15%), Positives = 31/117 (26%), Gaps = 29/117 (25%)
Query 565 KFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLD 624
+ L+GT+ S K +++ G H + C +
Sbjct 476 NWK-KLFGTS---------SQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVS 525
Query 625 THYSTENDVETIRASV-------------CAPCHASCA------TCQGPALTDCLSC 662
+ + +V C CH C TC G +C+ C
Sbjct 526 CQNVSRGRECVDKCNVLEGEPREFVENSECIQCHPECLPQVMNITCTGRGPDNCIQC 582
>sp|Q9XWD6|CED1_CAEEL Cell death abnormality protein 1 OS=Caenorhabditis
elegans OX=6239 GN=ced-1 PE=1 SV=1
Length=1111
Score = 40.6 bits (93), Expect = 0.068, Method: Composition-based stats.
Identities = 23/116 (20%), Positives = 38/116 (33%), Gaps = 18/116 (16%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTE 630
+G E P+ GC +T C +G + PG + +
Sbjct 510 FGANCEKRCKCPKGIGCDPITGECTCPAGLQGANCDIGCPEGSYGPGCKLHCKCVNGKCD 569
Query 631 NDVETIRASVCAP------CHASCATCQGPALTDC-LSCPSHASLDPVEQTCSRQS 679
+ C P C +C+ +G C LSCP + +CS+Q+
Sbjct 570 KETG---ECTCQPGFFGSDCSTTCS--KGKYGESCELSCPCS------DASCSKQT 614
>sp|Q8TE57|ATS16_HUMAN A disintegrin and metalloproteinase with
thrombospondin motifs 16 OS=Homo sapiens OX=9606 GN=ADAMTS16
PE=2 SV=3
Length=1224
Score = 40.6 bits (93), Expect = 0.080, Method: Composition-based stats.
Identities = 28/169 (17%), Positives = 47/169 (28%), Gaps = 28/169 (17%)
Query 548 VLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQ 607
L +E + N G ++++ GT + P +++ +
Sbjct 837 TLIVELLFQGRNPGVAWEYSMPRLGTEKQPPAQP------------------SYTWAIVR 878
Query 608 KSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHAS 667
C C G + + V C+ G +CP S
Sbjct 879 SECSVSCGGGQMTVREGCYRDLKFQVNMSF------CNPKTRPVTGLVPCKVSACPPSWS 932
Query 668 LDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEV 716
+ CSR +S P Q R+ + E A L P P
Sbjct 933 V-GNWSACSRTCGGGAQSRPVQCTRRVHYDSEPVP---ASLCPQPAPSS 977
>sp|Q06806|TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mus
musculus OX=10090 GN=Tie1 PE=1 SV=3
Length=1134
Score = 40.2 bits (92), Expect = 0.086, Method: Composition-based stats.
Identities = 32/168 (19%), Positives = 50/168 (30%), Gaps = 17/168 (10%)
Query 529 NDWAFMTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVL--YGTAPEGLPVPPESSG 586
N+ ++ T W E G + L+++N + + G + L G+A L V +G
Sbjct 158 NNGSYFNTLDWQEADDGRFQLQLQNV-QPPSSGIYSATYLEASPLGSAFFRLIVRGCGAG 216
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQV-----------LDTHYSTENDVET 635
+ C C G H CPPGF
Sbjct 217 RWGPGCVKDCPGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGTAGC 276
Query 636 IRASVCAPCHASCATCQGPALTDCL-SCPSHASLDPVEQTCSRQSQSS 682
+ C P C+ G + C +C C Q Q+
Sbjct 277 RGLTFCLPDPYGCSCGSGWRGSQCQEACAPGHFGADCRLQC--QCQNG 322
>sp|Q5G872|SCUB2_DANRE Signal peptide, CUB and EGF-like domain-containing
protein 2 OS=Danio rerio OX=7955 GN=scube2 PE=2
SV=1
Length=1010
Score = 40.2 bits (92), Expect = 0.089, Method: Composition-based stats.
Identities = 23/111 (21%), Positives = 40/111 (36%), Gaps = 5/111 (5%)
Query 585 SGCKTLTSSQACVVCEEGFSLHQKSCVQHC--PPGFAPQVLDTHYSTENDVETIRASVCA 642
G K LT ++C +E F +++C C PG V + Y+ + C+
Sbjct 334 KGFKLLTDERSCQDIDECFF--ERTCDHTCVNSPGSFQCVCNKGYTLYGLAHCGDINECS 391
Query 643 PCHASCA-TCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPP 692
+ C TC+ + C + L ++ C S PP +
Sbjct 392 FNNGGCEHTCENTMGSFGCHCRAGYKLHWNKKDCIEAEDSPLVPPPARPTL 442
>sp|Q8N446|ZN843_HUMAN Zinc finger protein 843 OS=Homo sapiens
OX=9606 GN=ZNF843 PE=1 SV=1
Length=348
Score = 39.8 bits (91), Expect = 0.089, Method: Composition-based stats.
Identities = 34/171 (20%), Positives = 51/171 (30%), Gaps = 19/171 (11%)
Query 566 FTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDT 625
+ L + L S+G + S Q C + +L + + P GF V
Sbjct 73 WPLQPHQAPASPLGRSHSSAGVRQGFSGQLCCWLTKEHTLAEALRLSPVPAGFWGPVEAD 132
Query 626 HYSTENDVETIRASVCAPC----------------HASCATCQGPALTDCLSCPSHASLD 669
+ C+ C H TC+G ++ PS + D
Sbjct 133 RPPANSHRRVCPFCCCS-CGDSVNEKTSLSQRVLPHPGEKTCRGGSVESVSLAPSSVAPD 191
Query 670 PVE--QTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVA 718
+ C + PP PR P L+PS LP V A
Sbjct 192 STSGLRPCGSPGSFLQHLPPSTLLPRPPFLYPGPPLSLQPLVPSGLPAVPA 242
>sp|F4KEL0|SBT55_ARATH Subtilisin-like protease SBT5.5 OS=Arabidopsis
thaliana OX=3702 GN=SBT5.5 PE=3 SV=2
Length=803
Score = 40.2 bits (92), Expect = 0.092, Method: Composition-based stats.
Identities = 13/50 (26%), Positives = 22/50 (44%), Gaps = 0/50 (0%)
Query 353 TTDLRQKCTESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSK 402
+ D R +GTS S P AG IAL + + ++ ++ T+
Sbjct 574 SIDRRVLDYNLDSGTSMSCPHVAGAIALLKSMHPTWSSAAIRSALMTTAS 623
>sp|Q96HD1|CREL1_HUMAN Protein disulfide isomerase CRELD1 OS=Homo
sapiens OX=9606 GN=CRELD1 PE=1 SV=3
Length=420
Score = 39.8 bits (91), Expect = 0.10, Method: Composition-based stats.
Identities = 18/86 (21%), Positives = 32/86 (37%), Gaps = 12/86 (14%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C+ + C+ ++C Q C G+ + + VC+ C
Sbjct 169 CEGEGTRGGSGHCDCQAGYGGEACGQ-CGLGYFEAERNASHL-----------VCSACFG 216
Query 647 SCATCQGPALTDCLSCPSHASLDPVE 672
CA C GP ++CL C +L ++
Sbjct 217 PCARCSGPEESNCLQCKKGWALHHLK 242
Score = 39.0 bits (89), Expect = 0.15, Method: Composition-based stats.
Identities = 22/86 (26%), Positives = 30/86 (35%), Gaps = 10/86 (12%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQ--HCPPGFAPQVLDTH-YSTENDVETIRASV 640
+ C S C+ C++G++LH CV C A D +TE E
Sbjct 218 CARCSGPEES-NCLQCKKGWALHHLKCVDIDECGTEGANCGADQFCVNTEGSYE------ 270
Query 641 CAPCHASCATCQGPALTDCLSCPSHA 666
C C +C C G C C
Sbjct 271 CRDCAKACLGCMGAGPGRCKKCSPGY 296
>sp|Q9Y2M2|SSUH2_HUMAN Protein SSUH2 homolog OS=Homo sapiens OX=9606
GN=SSUH2 PE=1 SV=2
Length=375
Score = 39.4 bits (90), Expect = 0.11, Method: Composition-based stats.
Identities = 37/202 (18%), Positives = 56/202 (28%), Gaps = 30/202 (15%)
Query 471 VTACLGEPNHITRLEHAQARLTLSYNRRGDLAI-HLVSPMGTRSTLLAARPHDYSADGFN 529
V A E L ++ S GDL I L R TL R +S +
Sbjct 71 VPAMTEEVAREALLSFVDSKCCYSSTVAGDLVIQELK-----RQTLCRYRLETFSESRIS 125
Query 530 DWAF--MTTHSWDEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGC 587
+W F T HS D G + + + + G P
Sbjct 126 EWTFQPFTNHSVDGPQRG---------------ASPRLWDIKVQG--PPMFQEDTRKFQV 168
Query 588 KTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPC-HA 646
+ + C C + C + + ++ R +CA
Sbjct 169 PHSSLVKECHKCHG----RGRYKCSGCHGAGTVRCPSCCGAKRKAKQSRRCQLCAGSGRR 224
Query 647 SCATCQGPALTDCLSCPSHASL 668
C+TC G C +C L
Sbjct 225 RCSTCSGRGNKTCATCKGEKKL 246
>sp|O88799|ZAN_MOUSE Zonadhesin OS=Mus musculus OX=10090 GN=Zan
PE=1 SV=1
Length=5376
Score = 40.2 bits (92), Expect = 0.11, Method: Composition-based stats.
Identities = 25/131 (19%), Positives = 36/131 (27%), Gaps = 22/131 (17%)
Query 575 PEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQH--CPPGFAPQVLDTHYSTEND 632
P P + G TS +A CEEG + + C P D H +
Sbjct 4515 PPCQPSCSDPDGHCEGTSPEAPSTCEEGCVCEPDYVLSNDKCVPSSECGCKDAHGVLIPE 4574
Query 633 VETIRASVCAP---CHASCATCQG---PALTDCL--------------SCPSHASLDPVE 672
+T + C C C P + CL CP+H+
Sbjct 4575 SKTWVSRGCTKNCTCKGGTVQCHDFSCPTGSRCLDNNEGNSNCVTYALKCPAHSLYTNCL 4634
Query 673 QTCSRQSQSSR 683
+C
Sbjct 4635 PSCLPSCSDPE 4645
Score = 39.4 bits (90), Expect = 0.18, Method: Composition-based stats.
Identities = 26/127 (20%), Positives = 42/127 (33%), Gaps = 28/127 (22%)
Query 572 GTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQ--HCPPGFAPQVLDTHYST 629
GT+PE S CK + C+ C+ G+ LH+ C+ HC L T
Sbjct 4650 GTSPE------VPSTCK-----EGCI-CQSGYVLHKNKCMLRIHCDCKDFQGSLIKTGQT 4697
Query 630 ENDVETIRASVCAPCHASCATCQGPALTDC--------------LSCPSHASLDPVEQTC 675
+ C C + + P+ T C + CP+++ TC
Sbjct 4698 WISSGCSKICTCKGGFFQCQSYKCPSGTQCEESEDGSSNCVSSTMKCPANSLYTHCLPTC 4757
Query 676 SRQSQSS 682
+
Sbjct 4758 LPSCSNP 4764
Score = 38.3 bits (87), Expect = 0.37, Method: Composition-based stats.
Identities = 24/128 (19%), Positives = 40/128 (31%), Gaps = 19/128 (15%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCV--QHCPPGFAPQVLDTHYSTENDVETIRASVC 641
+ + ++ + VCE + L + CV C A L T + C
Sbjct 4290 GASPRAPSTCREGCVCEADYVLREDKCVLRTQCGCKDAQGDLIPANKTWLTRGCAQKCTC 4349
Query 642 APCHASCATCQGPALTDC--------------LSCPSHASLDPVEQTCSRQSQSSR---E 684
+ C + P T+C L CP+H+ +C + E
Sbjct 4350 KGGNIHCWNFKCPLGTECKDSVDGGSNCTKIALQCPAHSHHTYCLPSCIPSCSNVNDRCE 4409
Query 685 SPPQQQPP 692
S Q+P
Sbjct 4410 STSLQRPS 4417
Score = 37.5 bits (85), Expect = 0.67, Method: Composition-based stats.
Identities = 23/124 (19%), Positives = 39/124 (31%), Gaps = 15/124 (12%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQ--HCPPGFAPQVLDTHYSTENDVETIRASVC 641
+ K ++ + VC+ G+ L + C+ C + T I++ C
Sbjct 3803 GTSPKGPSTCKEGCVCQPGYVLDKDKCILKIECGCRDTQGAVIPAGKTWLSTGCIQSCAC 3862
Query 642 APCHASCATCQGPALTDC----------LSCPSHASLDPVEQTCSRQSQS---SRESPPQ 688
C Q P T C L CP+H+ +C + S E
Sbjct 3863 VEGTIQCQNFQCPPGTYCNHNNNCAKIPLQCPAHSHFTSCLPSCPPSCANLDGSCEQTSP 3922
Query 689 QQPP 692
+ P
Sbjct 3923 KVPS 3926
Score = 37.5 bits (85), Expect = 0.68, Method: Composition-based stats.
Identities = 22/131 (17%), Positives = 43/131 (33%), Gaps = 24/131 (18%)
Query 583 ESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCA 642
E + K ++ + +C+ G+ +H+ CV +T + + +T + C
Sbjct 3205 EGTSPKVPSTCREGCICQPGYLMHKNKCV----LRIFCGCKNTQGAFISADKTWISRGCT 3260
Query 643 P---CHAS---CATCQGPALTDC--------------LSCPSHASLDPVEQTCSRQSQSS 682
C A C + P+ T C L CP+++ +C +
Sbjct 3261 QSCTCPAGAIHCRNFKCPSGTYCKNGDNGSSNCTEITLQCPTNSQFTDCLPSCVPSCSNR 3320
Query 683 RESPPQQQPPR 693
E P
Sbjct 3321 CEVTSPSVPSS 3331
>sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS=Homo
sapiens OX=9606 GN=EGFR PE=1 SV=2
Length=1210
Score = 39.8 bits (91), Expect = 0.13, Method: Composition-based stats.
Identities = 31/150 (21%), Positives = 48/150 (32%), Gaps = 19/150 (13%)
Query 547 WVLEIENTSEANNYGT----LTKFTLVLYGT---APEGLPVPPESSGCKTLTSSQACVVC 599
+ L + + +AN G + +L+G + ES + + SS
Sbjct 117 YALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNM 176
Query 600 EEGFSLHQ---KSCVQHCPPG--FAPQVLDTHYSTENDVETIRASVCAP------CHASC 648
F H + C CP G + + T+ + C CH C
Sbjct 177 SMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQC 236
Query 649 AT-CQGPALTDCLSCPSHASLDPVEQTCSR 677
A C GP +DCL C + TC
Sbjct 237 AAGCTGPRESDCLVCRKFRDEATCKDTCPP 266
>sp|P58459|ATS10_MOUSE A disintegrin and metalloproteinase with
thrombospondin motifs 10 OS=Mus musculus OX=10090 GN=Adamts10
PE=2 SV=3
Length=1104
Score = 39.4 bits (90), Expect = 0.16, Method: Composition-based stats.
Identities = 34/184 (18%), Positives = 52/184 (28%), Gaps = 33/184 (18%)
Query 577 GLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETI 636
P PP C Q + E +L C C PG +V+ + +
Sbjct 929 PQPRPPVLEAC------QGPMCPPEWATLDWSECTPSCGPGLRHRVVLCKSADQRSTLPP 982
Query 637 RASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRL-P 695
+ A S C CP + CS Q ++ +
Sbjct 983 GHCLPAAKPPSTMRCNLRR------CPPARWVTSEWGECSTQCGLGQQQRTVRCTSHTGQ 1036
Query 696 PEVEAGQRLRAGLLPSHLPEVVAGLSCAFIV--------------LVFVTVFLVLQLRSG 741
P E + LR PS + + A C +V + + + L Q S
Sbjct 1037 PSRECTEALR----PSTMQQCEA--KCDSVVPPGDGPEECKDVNKVAYCPLVLKFQFCSR 1090
Query 742 FSFR 745
FR
Sbjct 1091 AYFR 1094
>sp|P0DSV8|CRMB_VARV Cytokine response-modifying protein B OS=Variola
virus OX=10255 GN=OPG002 PE=3 SV=1
Length=349
Score = 39.0 bits (89), Expect = 0.16, Method: Composition-based stats.
Identities = 18/90 (20%), Positives = 31/90 (34%), Gaps = 10/90 (11%)
Query 592 SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATC 651
+ + + H C+ CPPG L ++ + C PC + T
Sbjct 26 TPPNGKCKDTEYKRHNLCCLS-CPPGTYASRL---------CDSKTNTQCTPCGSGTFTS 75
Query 652 QGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
+ L CLSC + + VE + +
Sbjct 76 RNNHLPACLSCNGRCNSNQVETRSCNTTHN 105
>sp|P0DSV7|CRMB_VAR67 Cytokine response-modifying protein B OS=Variola
virus (isolate Human/India/Ind3/1967) OX=587200 GN=OPG002
PE=1 SV=1
Length=349
Score = 39.0 bits (89), Expect = 0.16, Method: Composition-based stats.
Identities = 18/90 (20%), Positives = 31/90 (34%), Gaps = 10/90 (11%)
Query 592 SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATC 651
+ + + H C+ CPPG L ++ + C PC + T
Sbjct 26 TPPNGKCKDTEYKRHNLCCLS-CPPGTYASRL---------CDSKTNTQCTPCGSGTFTS 75
Query 652 QGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
+ L CLSC + + VE + +
Sbjct 76 RNNHLPACLSCNGRCNSNQVETRSCNTTHN 105
>sp|Q9Z132|RSPO1_MOUSE R-spondin-1 OS=Mus musculus OX=10090 GN=Rspo1
PE=1 SV=1
Length=265
Score = 38.6 bits (88), Expect = 0.16, Method: Composition-based stats.
Identities = 22/127 (17%), Positives = 37/127 (29%), Gaps = 25/127 (20%)
Query 585 SGCKTLTSSQACVVCE-EGFSLHQKS-------CVQHCPPGFAPQVLDTHYSTENDVETI 636
GC+ + C+ C + F L +++ C+ CPPG+ D
Sbjct 42 KGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYF------------DARNP 89
Query 637 RASVCAPCH-ASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLP 695
+ C C C C + C C L + C + P
Sbjct 90 DMNKCIKCKIEHCEACF--SHNFCTKCQEALYLH--KGRCYPACPEGSTAANSTMECGSP 145
Query 696 PEVEAGQ 702
+ E +
Sbjct 146 AQCEMSE 152
>sp|Q60675|LAMA2_MOUSE Laminin subunit alpha-2 OS=Mus musculus
OX=10090 GN=Lama2 PE=1 SV=2
Length=3118
Score = 39.4 bits (90), Expect = 0.16, Method: Composition-based stats.
Identities = 20/89 (22%), Positives = 26/89 (29%), Gaps = 12/89 (13%)
Query 595 ACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGP 654
AC G + K+ CPP N + C C+ C+T G
Sbjct 1009 ACDCSHLGNNCDPKTGQCICPPNTTG--EKCSECLPNTWGHSIVTGCKVCN--CSTV-GS 1063
Query 655 ALTDC------LSCPSHASLDPVEQTCSR 677
+ C SC S CSR
Sbjct 1064 LASQCNVNTGQCSCHPKFSGMKC-SECSR 1091
>sp|O88281|MEGF6_RAT Multiple epidermal growth factor-like domains
protein 6 OS=Rattus norvegicus OX=10116 GN=Megf6 PE=1 SV=1
Length=1574
Score = 39.4 bits (90), Expect = 0.16, Method: Composition-based stats.
Identities = 22/118 (19%), Positives = 31/118 (26%), Gaps = 7/118 (6%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCA---- 642
C L + C G H PG + L T + + C
Sbjct 623 CHRLYGACLCDPGLYGRFCHLACPPWAFGPGCSEDCLCEQSHTRSCNPKDGSCSCKAGFQ 682
Query 643 --PCHASCAT-CQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPE 697
C A C + GP +C + DPV C Q + Q +
Sbjct 683 GERCQAECESGFFGPGCRHRCTCQPGVACDPVSGECRTQCPPGYQGEDCGQECPVGTF 740
Score = 36.3 bits (82), Expect = 1.6, Method: Composition-based stats.
Identities = 23/95 (24%), Positives = 33/95 (35%), Gaps = 6/95 (6%)
Query 585 SGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPC 644
SG + + C C +G S H + CPPG+ + E P
Sbjct 1125 SGTFGVHCEEHC-ACRKGASCHHVTGACFCPPGWRGPHCEQACPRGWFGEACAQRCLCPT 1183
Query 645 HASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS 679
+ASC G +C CP + EQ C +
Sbjct 1184 NASCHHVTG----EC-RCPPGFTGLSCEQACQPGT 1213
Score = 33.6 bits (75), Expect = 8.7, Method: Composition-based stats.
Identities = 23/108 (21%), Positives = 33/108 (31%), Gaps = 13/108 (12%)
Query 571 YGTAPEGL-PVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
+G E L P E+ C + C H C+Q CP G +
Sbjct 1214 FGKDCEHLCQCPGETWACDPASGVCTCAA-----GYHGTGCLQRCPSGRYGP--GCEHI- 1265
Query 630 ENDVETIRASVCAPCHASCATCQGPALTDC-LSCPSHASLDPVEQTCS 676
+ + C P +C G DC L+CP C+
Sbjct 1266 ---CKCLNGGTCDPATGACYCPAGFLGADCSLACPQGRFGPSCAHVCA 1310
>sp|A8MUX0|KR161_HUMAN Keratin-associated protein 16-1 OS=Homo
sapiens OX=9606 GN=KRTAP16-1 PE=3 SV=1
Length=517
Score = 39.0 bits (89), Expect = 0.16, Method: Composition-based stats.
Identities = 27/141 (19%), Positives = 40/141 (28%), Gaps = 18/141 (13%)
Query 576 EGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQH-CPPGFAPQVLDTHYS------ 628
+ P P S + + E L CVQ C P P
Sbjct 250 DPSPCEPSCSESSICQPATCVALVCEPVCLRPVCCVQSSCEPPSVPSTCQEPSCCVSSIC 309
Query 629 ----TENDVETIRASVCAPCHASCATCQGPALTDC---LSCPSHASLDPVEQTCSRQSQS 681
+E + V +PC +C + + C +SCPS + +CS S +
Sbjct 310 QPICSEPSPCSPAVCVSSPCQPTCYVVK-RCPSVCPEPVSCPSTSCRPL---SCSPGSSA 365
Query 682 SRESPPQQQPPRLPPEVEAGQ 702
S P P
Sbjct 366 SAICRPTCPRTFYIPSSSKRP 386
Score = 37.1 bits (84), Expect = 0.77, Method: Composition-based stats.
Identities = 23/123 (19%), Positives = 32/123 (26%), Gaps = 9/123 (7%)
Query 573 TAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEND 632
T+ + + S VC S C C P T +
Sbjct 187 TSCQPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVCEPSCCQPVCP----TPTCSVTS 242
Query 633 VETIRASVCAPCHASCATCQGPALTDCLS--CPSHASLDPVEQTCSRQSQSSRESPPQQQ 690
+PC SC+ C++ C L PV C + S P Q
Sbjct 243 SCQAVCCDPSPCEPSCSESSICQPATCVALVCEP-VCLRPV--CCVQSSCEPPSVPSTCQ 299
Query 691 PPR 693
P
Sbjct 300 EPS 302
>sp|Q88WG0|ACCD2_LACPL Acetyl-coenzyme A carboxylase carboxyl
transferase subunit beta 2 OS=Lactiplantibacillus plantarum
(strain ATCC BAA-793 / NCIMB 8826 / WCFS1) OX=220668 GN=accD2
PE=3 SV=1
Length=281
Score = 38.6 bits (88), Expect = 0.17, Method: Composition-based stats.
Identities = 18/101 (18%), Positives = 31/101 (31%), Gaps = 3/101 (3%)
Query 618 FAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSR 677
F +++ + C CH C T C C L ++ +
Sbjct 7 FQAPTERQLAVRRDNIPDALLTRCPVCHEDCYTQDLGEFKVCPHCDYGFRLPAWQR--VQ 64
Query 678 QSQSSRESPPQQQPPRLPP-EVEAGQRLRAGLLPSHLPEVV 717
Q +S E + + ++L+ SHL E V
Sbjct 65 QLTASFEERDADLSAPVSFDDPAYLEKLQRAKAASHLNESV 105
>sp|C6VQ34|ACCD2_LACPJ Acetyl-coenzyme A carboxylase carboxyl
transferase subunit beta 2 OS=Lactiplantibacillus plantarum
(strain JDM1) OX=644042 GN=accD2 PE=3 SV=1
Length=281
Score = 38.6 bits (88), Expect = 0.17, Method: Composition-based stats.
Identities = 18/101 (18%), Positives = 31/101 (31%), Gaps = 3/101 (3%)
Query 618 FAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSR 677
F +++ + C CH C T C C L ++ +
Sbjct 7 FQAPTERQLAVRRDNIPDALLTRCPVCHEDCYTQDLGEFKVCPHCDYGFRLPAWQR--VQ 64
Query 678 QSQSSRESPPQQQPPRLPP-EVEAGQRLRAGLLPSHLPEVV 717
Q +S E + + ++L+ SHL E V
Sbjct 65 QLTASFEERDADLSAPVSFDDPAYLEKLQRAKAASHLNESV 105
>sp|Q9JLL0|CRIM1_MOUSE Cysteine-rich motor neuron 1 protein OS=Mus
musculus OX=10090 GN=Crim1 PE=2 SV=2
Length=1037
Score = 39.4 bits (90), Expect = 0.17, Method: Composition-based stats.
Identities = 21/120 (18%), Positives = 34/120 (28%), Gaps = 12/120 (10%)
Query 580 VPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRAS 639
P + G T+ S Q C C + F + + Y E + I +
Sbjct 643 CPVPACGNPTIRSGQCCPSCTDDFVVQK----PELSTPSICHAPGGEYFVEGETWNIDSC 698
Query 640 VCAPCHASCATCQGPALTDCLSCPSHASLDP--VEQTCSRQSQSSRESPPQQQPPRLPPE 697
CH+ C+ CP +P + +C Q P +P
Sbjct 699 TQCTCHSGRVLCETEV------CPPLLCQNPSRTQDSCCPQCTDDPPQPSTSHNESVPSY 752
>sp|O89943|TAT_HV1SE Protein Tat OS=Human immunodeficiency virus
type 1 group M subtype G (isolate SE6165) OX=388824 GN=tat
PE=3 SV=1
Length=101
Score = 35.9 bits (81), Expect = 0.20, Method: Composition-based stats.
Identities = 14/85 (16%), Positives = 21/85 (25%), Gaps = 2/85 (2%)
Query 630 ENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQ 689
+ C C C CQ L L + + QS + P +
Sbjct 14 PGSQPKTPCNKCF-CKVCCWHCQVCFLNKGLGISYGRKKRKHRRG-TPQSSKGHQDPVPK 71
Query 690 QPPRLPPEVEAGQRLRAGLLPSHLP 714
QP G + + S
Sbjct 72 QPLPTTRGNPTGPKESKKEVASKAE 96
>sp|Q80T91|MEG11_MOUSE Multiple epidermal growth factor-like domains
protein 11 OS=Mus musculus OX=10090 GN=Megf11 PE=1 SV=3
Length=1091
Score = 39.0 bits (89), Expect = 0.23, Method: Composition-based stats.
Identities = 21/94 (22%), Positives = 25/94 (27%), Gaps = 9/94 (10%)
Query 583 ESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCA 642
+ S C G++ C CPPG S EN C+
Sbjct 536 DCSHADGCDPVTGHCCCLAGWT--GIRCDSTCPPGRWGPNCSVSCSCEN------GGSCS 587
Query 643 PCHASCATCQGPALTDCLS-CPSHASLDPVEQTC 675
P SC G C CP Q C
Sbjct 588 PEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPC 621
Score = 36.7 bits (83), Expect = 1.2, Method: Composition-based stats.
Identities = 28/156 (18%), Positives = 37/156 (24%), Gaps = 17/156 (11%)
Query 575 PEGLPVPPESSGCKT---LTSSQACVVCEEGFSL----HQKSCVQHCPPGFAPQVLDTHY 627
E P + C+ + C + C Q CPPG Q
Sbjct 215 EELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQ------ 268
Query 628 STENDVETIRASVCAPCHASCATCQGPALTDCL-SCPSHASLDPVEQTCSRQSQSSRESP 686
+ D C C G C CP Q C + +
Sbjct 269 NCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGTFGFLCSQRC--DCHNGGQCS 326
Query 687 PQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSC 722
P P + G + L P L L C
Sbjct 327 PATGACECEPGYK-GPSCQERLCPEGLHGPGCTLPC 361
>sp|Q5T870|PRR9_HUMAN Proline-rich protein 9 OS=Homo sapiens OX=9606
GN=PRR9 PE=4 SV=1
Length=116
Score = 36.3 bits (82), Expect = 0.24, Method: Composition-based stats.
Identities = 23/95 (24%), Positives = 31/95 (33%), Gaps = 16/95 (17%)
Query 607 QKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHA 666
++ C Q C P T+ + VC P TCQ P CL
Sbjct 5 EQQCKQPCVPPPCLP------KTQEQCQAKAEEVCLP------TCQHPCQDKCLVQAQEV 52
Query 667 SLDPVEQT----CSRQSQSSRESPPQQQPPRLPPE 697
L +++ C +Q Q P Q Q P E
Sbjct 53 CLSQCQESSQEKCPQQGQEPYLPPCQDQCPPQCAE 87
>sp|A2A5X5|KR161_MOUSE Keratin-associated protein 16-1 OS=Mus
musculus OX=10090 GN=Krtap16-1 PE=3 SV=1
Length=502
Score = 38.6 bits (88), Expect = 0.25, Method: Composition-based stats.
Identities = 22/123 (18%), Positives = 32/123 (26%), Gaps = 9/123 (7%)
Query 564 TKFTLVLYGTAPEGLPVPPESSGC--KTLTSSQACV-VCEEGFSLHQKSCVQHCPPGFAP 620
+ LV T + S C + + S C VC E V C
Sbjct 38 QTWQLV---TCEDSCGSSGCGSQCCQPSCSVSSCCQPVCCEATICEPSCSVSSCAQPVCC 94
Query 621 QVLDTH-YSTENDVETIRASVCAPCHASCA--TCQGPALTDCLSCPSHASLDPVEQTCSR 677
+ + C SC+ TC P + C S+ + C
Sbjct 95 EATICEPSCSMGSCCQPVCCEATICEPSCSVSTCAQPVCCEATMCQPSCSVSSCQPVCCE 154
Query 678 QSQ 680
S
Sbjct 155 TSS 157
>sp|P98092|HMCT_BOMMO Hemocytin OS=Bombyx mori OX=7091 PE=2 SV=1
Length=3133
Score = 39.0 bits (89), Expect = 0.26, Method: Composition-based stats.
Identities = 23/137 (17%), Positives = 40/137 (29%), Gaps = 21/137 (15%)
Query 577 GLPVPPESSGCKTLTSSQ---ACVVC----EEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
+ S + S+ C E Q +CV+ C P + + Y
Sbjct 506 PMQCDEVCSNYDSCVSACPVETCDNILYYAETTARCEQDTCVEGCKPKKSCP-EGSVYKN 564
Query 630 ENDVETIRASVCAPCHASCATCQGPA---------LTDCLSCPSHASLDPVE-QTCSRQS 679
++ E + + C P C T G C +C Q CS ++
Sbjct 565 DSTTECVPRAKCKP---VCMTLDGGREVLEGEIIEEDACHTCRCSKKHKVCTGQPCSTEA 621
Query 680 QSSRESPPQQQPPRLPP 696
+ + +P P
Sbjct 622 PRIQATSSSAEPATERP 638
>sp|P54643|SP87_DICDI Spore coat protein SP87 OS=Dictyostelium
discoideum OX=44689 GN=pspD PE=2 SV=1
Length=677
Score = 38.6 bits (88), Expect = 0.27, Method: Composition-based stats.
Identities = 25/128 (20%), Positives = 35/128 (27%), Gaps = 13/128 (10%)
Query 583 ESSGCKTLTS-SQACVVCEEGFSLHQKSCVQHCPPGF--------APQVLDTHYSTEN-D 632
CK S+ CV E + C + CPPG + H
Sbjct 486 RGFECKIRHDGSKCCVRSERPHPPQHEKCNKRCPPGHECKVDQHGKECCVVAHRPPPKCS 545
Query 633 VETIRASVCAPCHASCATCQGPALTDC-LSCPSHASLDPVEQTCSRQSQSSRESPPQQQP 691
+ C H C C L CP + ++ PP +
Sbjct 546 LRCPPRHECRVNHFGEECCVKVHHDKCSLRCPPGHECKVDQHG--KECCVVAHRPPPKCS 603
Query 692 PRLPPEVE 699
R PP+ E
Sbjct 604 LRCPPKHE 611
>sp|Q02763|TIE2_HUMAN Angiopoietin-1 receptor OS=Homo sapiens
OX=9606 GN=TEK PE=1 SV=2
Length=1124
Score = 38.6 bits (88), Expect = 0.29, Method: Composition-based stats.
Identities = 21/124 (17%), Positives = 34/124 (27%), Gaps = 12/124 (10%)
Query 570 LYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
L+ +A L V + + C C H+ + CPPGF + +
Sbjct 198 LFTSAFTRLIVRRCEAQKWGPECNHLCTACMNNGVCHEDTGECICPPGFMGRTCEKACEL 257
Query 630 ENDVETIRAS-----------VCAPCHASCATCQGPALTDC-LSCPSHASLDPVEQTCSR 677
T + C P C+ G C +C + CS
Sbjct 258 HTFGRTCKERCSGQEGCKSYVFCLPDPYGCSCATGWKGLQCNEACHPGFYGPDCKLRCSC 317
Query 678 QSQS 681
+
Sbjct 318 NNGE 321
>sp|Q9XF14|BSD2_MAIZE Protein BUNDLE SHEATH DEFECTIVE 2, chloroplastic
OS=Zea mays OX=4577 GN=BSD2 PE=2 SV=1
Length=129
Score = 36.3 bits (82), Expect = 0.30, Method: Composition-based stats.
Identities = 25/115 (22%), Positives = 36/115 (31%), Gaps = 5/115 (4%)
Query 569 VLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCV---QHCPPGFAPQVLDT 625
+L +AP + P S CK L ++ HQK Q C A
Sbjct 17 LLKASAPLLISFRPVSRHCKNLCIKTKATENDQSAKKHQKVKSILCQDCEGNGAIVCTKC 76
Query 626 HYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQ 680
+ N V+ A + C C+G C +C L T +Q
Sbjct 77 EGNGVNSVDYFEGRFKAG--SLCWLCRGKREILCGNCNGAGFLGGFLSTFDETAQ 129
>sp|Q3U492|KCP_MOUSE Kielin/chordin-like protein OS=Mus musculus
OX=10090 GN=Kcp PE=1 SV=2
Length=1550
Score = 38.6 bits (88), Expect = 0.30, Method: Composition-based stats.
Identities = 23/119 (19%), Positives = 32/119 (27%), Gaps = 18/119 (15%)
Query 582 PESSGCKTLTSSQACVVCEEGF-SLHQKSCVQHC---PPGFAPQVLDTHYSTENDVETIR 637
PE S S + +C +G + Q CV C G + +
Sbjct 968 PEGSSWVPADSPCSSCMCHKGIITCAQVQCVSACIWPQEGPSDCCPQCSGCEHGGRKYEP 1027
Query 638 ASVCAPCHASCATC------QGPALTDC--------LSCPSHASLDPVEQTCSRQSQSS 682
P C C +GP C + CP L P Q C +
Sbjct 1028 GESFQPGADPCEVCICKQKREGPPSLHCSRRQCPSLVGCPPSQLLPPGPQHCCPTCAQA 1086
Score = 37.5 bits (85), Expect = 0.66, Method: Composition-based stats.
Identities = 21/128 (16%), Positives = 40/128 (31%), Gaps = 9/128 (7%)
Query 572 GTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEN 631
G + P ++ C+ T + + C ++ C P +L+ +
Sbjct 497 GQNFTDVDSPCQTCYCEDGTVRCSLINCPFTTCAKPQNGPGQCCPKCPDCILEAQVFVDG 556
Query 632 DVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQ-----SQSSRESP 686
+ C C +G A +CPS + P+ TC + + +E P
Sbjct 557 ERFPHPRDPCQEC----WCQEGQAHCQLRACPSAPCVHPLPGTCCKNDCTGCAFGGKEYP 612
Query 687 PQQQPPRL 694
P
Sbjct 613 NGADFPHP 620
>sp|Q5ND28|SREC_MOUSE Scavenger receptor class F member 1 OS=Mus
musculus OX=10090 GN=Scarf1 PE=1 SV=1
Length=820
Score = 38.3 bits (87), Expect = 0.32, Method: Composition-based stats.
Identities = 21/101 (21%), Positives = 29/101 (29%), Gaps = 7/101 (7%)
Query 579 PVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRA 638
P C S C H C C PG E+
Sbjct 219 PECSRKCQCVRGQCSVTSGHCSCPPGFHGIRCELPCNPGHY-----GAQCKESCGHCELN 273
Query 639 SVCAPCHASCATCQ-GPALTDC-LSCPSHASLDPVEQTCSR 677
+ C+P +C +C+ G T C CP+ + C R
Sbjct 274 ATCSPVTGNCESCKPGWNGTQCKQPCPAGTFGERCTGQCPR 314
>sp|Q61001|LAMA5_MOUSE Laminin subunit alpha-5 OS=Mus musculus
OX=10090 GN=Lama5 PE=1 SV=4
Length=3718
Score = 38.6 bits (88), Expect = 0.32, Method: Composition-based stats.
Identities = 26/120 (22%), Positives = 33/120 (28%), Gaps = 23/120 (19%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEND-----VETIRASVC 641
CK + Q C C EG+ ++ Q C P C
Sbjct 2044 CKAGVTGQRCDRCLEGYFGFEQC--QGCRPCACGPAAKGSECHPQSGQCHCQPGTTGPQC 2101
Query 642 APC--------HASCATCQ------GPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPP 687
C C CQ P C CP S + + TCS+Q Q P
Sbjct 2102 LECAPGYWGLPEKGCRRCQCPRGHCDPHTGHCT-CPPGLSGERCD-TCSQQHQVPVPGKP 2159
>sp|A6BM72|MEG11_HUMAN Multiple epidermal growth factor-like domains
protein 11 OS=Homo sapiens OX=9606 GN=MEGF11 PE=1 SV=3
Length=1044
Score = 38.3 bits (87), Expect = 0.33, Method: Composition-based stats.
Identities = 29/156 (19%), Positives = 39/156 (25%), Gaps = 17/156 (11%)
Query 575 PEGLPVPPESSGCKT---LTSSQACVVCEEGFSL----HQKSCVQHCPPGFAPQVLDTHY 627
E P + C+ + C + C Q CPPG Q
Sbjct 216 EELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQ------ 269
Query 628 STENDVETIRASVCAPCHASCATCQGPALTDCL-SCPSHASLDPVEQTCSRQSQSSRESP 686
+ D C C G C CP + Q C + +
Sbjct 270 NCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHC--DCHNGGQCS 327
Query 687 PQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSC 722
P P + G R + L P L L C
Sbjct 328 PTTGACECEPGYK-GPRCQERLCPEGLHGPGCTLPC 362
>sp|Q8CIZ8|VWF_MOUSE von Willebrand factor OS=Mus musculus OX=10090
GN=Vwf PE=1 SV=2
Length=2813
Score = 38.3 bits (87), Expect = 0.35, Method: Composition-based stats.
Identities = 25/141 (18%), Positives = 45/141 (32%), Gaps = 10/141 (7%)
Query 540 DEDPSGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVC 599
DE+ + ++ L + + ++T+ G + +P C SS V+
Sbjct 2089 DENGANDFTLRDGTVTTDWKR-LVQEWTVQQPGYTCQAVP----EEQCPVSDSSHCQVLL 2143
Query 600 EEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDC 659
F+ C + P + + V + AS C S C
Sbjct 2144 SASFAE----CHKVIAPATFHTICQQDSCHQERVCEVIASYAHLCRTSGVCVDWRTTDFC 2199
Query 660 -LSCPSHASLDPVEQTCSRQS 679
+SCP + E+ C R
Sbjct 2200 AMSCPPSLVYNHCERGCPRHC 2220
>sp|O02466|ILPR_BRALA Insulin-like peptide receptor OS=Branchiostoma
lanceolatum OX=7740 PE=2 SV=1
Length=1363
Score = 38.3 bits (87), Expect = 0.37, Method: Composition-based stats.
Identities = 13/81 (16%), Positives = 27/81 (33%), Gaps = 14/81 (17%)
Query 579 PVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRA 638
P + + +T + + LH + C+ CP G+ + +
Sbjct 260 PDTYQYKDRRCITEEECPNTTNSVWKLHHRKCIPECPSGYTTDINNP------------- 306
Query 639 SVCAPCHASC-ATCQGPALTD 658
+C C C +C+G +
Sbjct 307 RLCTECEGQCPKSCKGGLVDS 327
>sp|Q8BFU0|RSPO2_MOUSE R-spondin-2 OS=Mus musculus OX=10090 GN=Rspo2
PE=1 SV=1
Length=243
Score = 37.5 bits (85), Expect = 0.37, Method: Composition-based stats.
Identities = 23/117 (20%), Positives = 34/117 (29%), Gaps = 23/117 (20%)
Query 585 SGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCA-P 643
C + S C C+ GF LH+ C CP GFAP C
Sbjct 99 ENCDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLDETME--------------CVEG 144
Query 644 CHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEA 700
C + G + +C L+ + + P + P E+
Sbjct 145 CEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIVK--------KPAKDTIPCPTIAES 193
>sp|Q9IBG7|KCP_XENLA Kielin/chordin-like protein OS=Xenopus laevis
OX=8355 GN=kcp PE=2 SV=1
Length=2327
Score = 38.3 bits (87), Expect = 0.40, Method: Composition-based stats.
Identities = 26/142 (18%), Positives = 40/142 (28%), Gaps = 29/142 (20%)
Query 575 PEGLPVPPESSGCKTLTS--------SQAC--VVCEEGFSLHQKSCVQHCPPGFAPQVLD 624
P G P + C+ +Q C ++C E F + + C Q CP A
Sbjct 1093 PNGADFPHPTDKCRQCHCINGNVQCLAQRCPPLLCAEPFPVPGECCPQ-CPVPPADCPYS 1151
Query 625 THYSTENDVETIRASVCAPC--HASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS--- 679
+ C C + TCQ C L P++ C R
Sbjct 1152 GVTYRHMQRFYDPSDKCRDCICNNGTVTCQRK------PCAPTPCLHPLQGDCCRSCDGC 1205
Query 680 -------QSSRESPPQQQPPRL 694
+ + P P +
Sbjct 1206 LMSGKELANGEQFPQPSDPCSV 1227
>sp|Q8AWW5|CRIM1_CHICK Cysteine-rich motor neuron 1 protein OS=Gallus
gallus OX=9031 GN=CRIM1 PE=2 SV=1
Length=1048
Score = 38.3 bits (87), Expect = 0.41, Method: Composition-based stats.
Identities = 19/120 (16%), Positives = 32/120 (27%), Gaps = 12/120 (10%)
Query 580 VPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRAS 639
P + G T+ Q C C + + + Y E + I +
Sbjct 655 CPVPNCGNPTIHPGQCCPSCPDEIIVQKPELTS----PSICHAPGGEYFVEGETWNIDSC 710
Query 640 VCAPCHASCATCQGPALTDCLSCPSHASLDPV--EQTCSRQSQSSRESPPQQQPPRLPPE 697
CH+ C+ CP +P + +C Q P +P
Sbjct 711 TQCTCHSGRVLCETEV------CPPLLCQNPTRTQDSCCPQCPDEPLQPSLSSNVSMPSY 764
>sp|Q6UXX9|RSPO2_HUMAN R-spondin-2 OS=Homo sapiens OX=9606 GN=RSPO2
PE=1 SV=2
Length=243
Score = 37.1 bits (84), Expect = 0.41, Method: Composition-based stats.
Identities = 26/133 (20%), Positives = 45/133 (34%), Gaps = 12/133 (9%)
Query 585 SGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDV-ETIRASVCAP 643
C + S C C+ GF LH+ C CP GFAP +V C+
Sbjct 99 ENCDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLEETMECVEGCEVGHWSEWGTCSR 158
Query 644 CHASC----------ATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPR 693
+ +C + D + CP+ A + T R + +P ++
Sbjct 159 NNRTCGFKWGLETRTRQIVKKPVKDTILCPTIAESRRCKMT-MRHCPGGKRTPKAKEKRN 217
Query 694 LPPEVEAGQRLRA 706
+ + +R +
Sbjct 218 KKKKRKLIERAQE 230
>sp|Q9UK23|NAGPA_HUMAN N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
OS=Homo sapiens OX=9606 GN=NAGPA
PE=1 SV=2
Length=515
Score = 37.9 bits (86), Expect = 0.43, Method: Composition-based stats.
Identities = 17/100 (17%), Positives = 28/100 (28%), Gaps = 16/100 (16%)
Query 581 PPESSGCKTLTSSQA-CVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRAS 639
P S T + C G + ++ + PG H+
Sbjct 364 PSNCSQHGLCTETGCRCDAGWTGSNCSEECPLGWHGPGCQRPCKCEHHC----------- 412
Query 640 VCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS 679
PC C + CL P A+L E + ++
Sbjct 413 ---PCDPKTGNCSVSRVKQCL-QPPEATLRAGELSFFTRT 448
>sp|Q67UE8|LYP4_ORYSJ LysM domain-containing GPI-anchored protein
LYP4 OS=Oryza sativa subsp. japonica OX=39947 GN=LYP4 PE=1
SV=1
Length=401
Score = 37.5 bits (85), Expect = 0.46, Method: Composition-based stats.
Identities = 25/158 (16%), Positives = 50/158 (32%), Gaps = 16/158 (10%)
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQ-HCPPGFAPQVLDTHYSTENDVETI 636
+P+P +S T+ V +++ CVQ C PG ++ ++
Sbjct 218 VPLPACTSSFPAFTADYGLAVANGTYAVTANRCVQCSCGPGNLDLFCVPAPLADSTCSSM 277
Query 637 RASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCS-----RQSQSSRESPPQQQP 691
+ + + + + SC ++ T Q + PP P
Sbjct 278 QCANSSMMLGNFTLLMTSSGCSVTSCSYGGFVNGTILTTLTTALKPQCPGPHQYPPLIPP 337
Query 692 P----------RLPPEVEAGQRLRAGLLPSHLPEVVAG 719
P P + + + AG+ P+ P +G
Sbjct 338 PTSSFFETYLGPSPTPMASEGGVMAGMAPTSTPAASSG 375
>sp|Q9L9F3|NOVO_STRNV 8-demethylnovobiocic acid C(8)-methyltransferase
OS=Streptomyces niveus OX=193462 GN=novO PE=1 SV=2
Length=230
Score = 37.1 bits (84), Expect = 0.47, Method: Composition-based stats.
Identities = 14/51 (27%), Positives = 18/51 (35%), Gaps = 1/51 (2%)
Query 500 DLAIHLVSPMGTRSTLLAARPHDYSADGFNDW-AFMTTHSWDEDPSGEWVL 549
D + L P G P D+ GF W F+ WD + W L
Sbjct 130 DTMLRLAKPGGAVLNCSFIHPSDFDESGFRAWVTFLNQRPWDSEMQIVWAL 180
>sp|B3EWZ3|CADN_ACRMI Coadhesin (Fragment) OS=Acropora millepora
OX=45264 PE=1 SV=1
Length=1675
Score = 37.9 bits (86), Expect = 0.48, Method: Composition-based stats.
Identities = 21/134 (16%), Positives = 32/134 (24%), Gaps = 23/134 (17%)
Query 580 VPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCP--------PGFAPQVLDTHY---- 627
C + C + + VQ CP G +
Sbjct 244 QRSRQRTCTNPSPKNGGTDCSGPSTQSEPCQVQFCPVDGGWSAWSGLSRCTRACGGGRQY 303
Query 628 ---STENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQ--TCSRQSQSS 682
+ N C + TC T C CP H P +C+R
Sbjct 304 QSRTCSNPFPGHGGRDCVGVRSLSFTCN----TQC--CPVHGGWSPWGSFSSCTRTCGGG 357
Query 683 RESPPQQQPPRLPP 696
++S + P
Sbjct 358 QKSRTRVCNSPAPS 371
>sp|P29825|VT2_MYXVL Tumor necrosis factor soluble receptor OS=Myxoma
virus (strain Lausanne) OX=31530 GN=m002L PE=3 SV=1
Length=326
Score = 37.1 bits (84), Expect = 0.51, Method: Composition-based stats.
Identities = 17/83 (20%), Positives = 24/83 (29%), Gaps = 9/83 (11%)
Query 599 CEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTD 658
C C CPPG L S +VC+PC T
Sbjct 28 CRGNDYEKDGLCCTSCPPGSYASRLCGPGSD---------TVCSPCKNETFTASTNHAPA 78
Query 659 CLSCPSHASLDPVEQTCSRQSQS 681
C+SC + E +++
Sbjct 79 CVSCRGRCTGHLSESQSCDKTRD 101
>sp|O15230|LAMA5_HUMAN Laminin subunit alpha-5 OS=Homo sapiens
OX=9606 GN=LAMA5 PE=1 SV=8
Length=3695
Score = 37.9 bits (86), Expect = 0.52, Method: Composition-based stats.
Identities = 26/111 (23%), Positives = 32/111 (29%), Gaps = 7/111 (6%)
Query 585 SGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPC 644
GC AC EG H +S HC PG + C C
Sbjct 2062 DGCGGCRP-CACGPAAEGSECHPQSGQCHCRPGTMGP--QCRECAPG-YWGLPEQGCRRC 2117
Query 645 HASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLP 695
C P C +CP S + + TCS+Q Q P
Sbjct 2118 QCPGGRC-DPHTGRC-NCPPGLSGERCD-TCSQQHQVPVPGGPVGHSIHCE 2165
>sp|P68637|CRMB_CAMPS Soluble TNF receptor II OS=Camelpox virus
(strain CMS) OX=203172 GN=OPG002 PE=3 SV=1
Length=349
Score = 37.1 bits (84), Expect = 0.54, Method: Composition-based stats.
Identities = 19/93 (20%), Positives = 31/93 (33%), Gaps = 10/93 (11%)
Query 589 TLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASC 648
T + + + H C+ CPPG L ++ + C PC +
Sbjct 23 TPYAPSNGKCKDNEYKRHNLCCLS-CPPGTYASRL---------CDSKTNTQCTPCGSGT 72
Query 649 ATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
T + L CLSC + VE + +
Sbjct 73 FTSRNNHLPACLSCNGRCDSNQVETRSCNTTHN 105
>sp|P68636|CRMB_CAMPM Soluble TNF receptor II OS=Camelpox virus
(strain M-96) OX=203173 GN=OPG002 PE=3 SV=1
Length=349
Score = 37.1 bits (84), Expect = 0.54, Method: Composition-based stats.
Identities = 19/93 (20%), Positives = 31/93 (33%), Gaps = 10/93 (11%)
Query 589 TLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASC 648
T + + + H C+ CPPG L ++ + C PC +
Sbjct 23 TPYAPSNGKCKDNEYKRHNLCCLS-CPPGTYASRL---------CDSKTNTQCTPCGSGT 72
Query 649 ATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
T + L CLSC + VE + +
Sbjct 73 FTSRNNHLPACLSCNGRCDSNQVETRSCNTTHN 105
>sp|Q02858|TIE2_MOUSE Angiopoietin-1 receptor OS=Mus musculus
OX=10090 GN=Tek PE=1 SV=2
Length=1122
Score = 37.5 bits (85), Expect = 0.57, Method: Composition-based stats.
Identities = 23/118 (19%), Positives = 36/118 (31%), Gaps = 12/118 (10%)
Query 570 LYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
L+ +A L V + S+ C C+ H+ + CPPGF + +
Sbjct 198 LFTSAFTRLIVRRCEAQKWGPDCSRPCTTCKNNGVCHEDTGECICPPGFMGRTCEKACEP 257
Query 630 ENDVETIRAS-----------VCAPCHASCATCQGPALTDC-LSCPSHASLDPVEQTC 675
T + C P C+ G C +CPS + C
Sbjct 258 HTFGRTCKERCSGPEGCKSYVFCLPDPYGCSCATGWRGLQCNEACPSGYYGPDCKLRC 315
>sp|Q6ZWJ8|KCP_HUMAN Kielin/chordin-like protein OS=Homo sapiens
OX=9606 GN=KCP PE=2 SV=3
Length=1568
Score = 37.5 bits (85), Expect = 0.59, Method: Composition-based stats.
Identities = 22/119 (18%), Positives = 31/119 (26%), Gaps = 18/119 (15%)
Query 582 PESSGCKTLTSSQACVVCEEGF-SLHQKSCVQHCPPGFAPQ---VLDTHYSTENDVETIR 637
PE S S+ + VC EG + + C+ C +
Sbjct 969 PEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCSDCEHEGRKYEP 1028
Query 638 ASVCAPCHASCATC------QGP-----ALTDC---LSCPSHASLDPVEQTCSRQSQSS 682
P C C +GP C + CP L P Q C +
Sbjct 1029 GESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEA 1087
>sp|Q92743|HTRA1_HUMAN Serine protease HTRA1 OS=Homo sapiens OX=9606
GN=HTRA1 PE=1 SV=1
Length=480
Score = 37.1 bits (84), Expect = 0.60, Method: Composition-based stats.
Identities = 25/141 (18%), Positives = 41/141 (29%), Gaps = 5/141 (4%)
Query 576 EGLPVPPESSGCKTLTSSQACVVCEE-GFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
E PP+ C+ + AC CE G +Q P G Q + +
Sbjct 42 EPARCPPQPEHCEGGRARDACGCCEVCGAPEGAACGLQEGPCGEGLQCVVPFGVPASATV 101
Query 635 TIRA----SVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQ 690
RA VCA C + C + + + + Q Q+
Sbjct 102 RRRAQAGLCVCASSEPVCGSDANTYANLCQLRAASRRSERLHRPPVIVLQRGACGQGQED 161
Query 691 PPRLPPEVEAGQRLRAGLLPS 711
P L + + + P+
Sbjct 162 PNSLRHKYNFIADVVEKIAPA 182
>sp|Q06807|TIE2_BOVIN Angiopoietin-1 receptor OS=Bos taurus OX=9913
GN=TEK PE=2 SV=1
Length=1125
Score = 37.5 bits (85), Expect = 0.63, Method: Composition-based stats.
Identities = 28/163 (17%), Positives = 46/163 (28%), Gaps = 18/163 (11%)
Query 570 LYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
L+ +A L V + ++ C C H+ + CPPGF + +
Sbjct 198 LFTSAFTRLIVRRCEAQKWGPECNRICTACMNNGICHEDTGECICPPGFMGRTCEKACEP 257
Query 630 ENDVETIRAS-----------VCAPCHASCATCQGPALTDC-LSCPSHASLDPVEQTCS- 676
T + C P C+ G C +C + CS
Sbjct 258 HTFGRTCKERCSEPEGCKSFVFCLPDPYGCSCATGWKGLQCNEACQPGYYGPDCKLRCSC 317
Query 677 ---RQSQSSRESPPQQQPPRLPPEVEAGQRLRAGL--LPSHLP 714
+ + L E E R+ + LP H+
Sbjct 318 TNGEKCDRFQGCLCSPGRQGLQCEKEGVPRMTPKIEDLPDHIE 360
>sp|Q8VHS2|CRUM1_MOUSE Protein crumbs homolog 1 OS=Mus musculus
OX=10090 GN=Crb1 PE=1 SV=3
Length=1405
Score = 37.5 bits (85), Expect = 0.68, Method: Composition-based stats.
Identities = 33/152 (22%), Positives = 57/152 (38%), Gaps = 8/152 (5%)
Query 580 VPPESSG--CKTLTSSQACVVCEEGFSL--HQKSCVQHCPPGFAPQVLDTHYSTENDVET 635
PP SG C+T T+S +C+ G + + V CPPG+A + +T ++
Sbjct 97 CPPGYSGLNCETATNSCGGNLCQHGGTCRKDPEHPVCICPPGYAGRFCETDHNECASSPC 156
Query 636 IRASVCAPCHA--SCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPP-QQQPP 692
++C SC G C DP + ++ R + Q+
Sbjct 157 HNGAMCQDGINGYSCFCVPGYQGRHCDLEVDECVSDPCKNEAVCLNEIGRYTCVCPQEFS 216
Query 693 RLPPEVEAGQ-RLRAGLLPSHLPEVVAGLSCA 723
+ E+E + R + L + + G SC
Sbjct 217 GVNCELEIDECRSQPCLHGATCQDAPGGYSCD 248
>sp|O75095|MEGF6_HUMAN Multiple epidermal growth factor-like domains
protein 6 OS=Homo sapiens OX=9606 GN=MEGF6 PE=1 SV=4
Length=1541
Score = 37.5 bits (85), Expect = 0.70, Method: Composition-based stats.
Identities = 22/92 (24%), Positives = 28/92 (30%), Gaps = 10/92 (11%)
Query 593 SQACVVCEEGFSLHQKSCVQHCPPGFAPQ-VLDTHYSTENDVETIRASVCAP----CHAS 647
+Q C C G + H + CPPGF + + C CH +
Sbjct 1129 AQRC-SCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPA 1187
Query 648 CATCQ---GPALTDCLS-CPSHASLDPVEQTC 675
TC G C CP EQ C
Sbjct 1188 TGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLC 1219
Score = 37.5 bits (85), Expect = 0.72, Method: Composition-based stats.
Identities = 21/112 (19%), Positives = 29/112 (26%), Gaps = 13/112 (12%)
Query 572 GTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEN 631
G G + + C + + C PGF Q +
Sbjct 1323 GLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQA--CEHPCPP 1380
Query 632 DVETIRASVCAPCHASCATCQGPALTDCLS----CPSHASLDPVEQTCSRQS 679
A C C CQ A D +S CP+ E+ C S
Sbjct 1381 GFHG------AGCQGLCW-CQHGAPCDPISGRCLCPAGFHGHFCERGCEPGS 1425
Score = 36.3 bits (82), Expect = 1.6, Method: Composition-based stats.
Identities = 24/100 (24%), Positives = 31/100 (31%), Gaps = 12/100 (12%)
Query 586 GCKTLTSSQACVVCEEGFSLHQKSCVQHCPPG-FAPQVLDTHYSTENDVETIRASVCA-- 642
+ C G+ H SC Q CPPG + P C
Sbjct 1180 ENPACHPATGTCSCAAGY--HGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCP 1237
Query 643 ------PCHASCATCQ-GPALTDCLSCPSHASLDPVEQTC 675
C+ +C + GP T C A+ DPV TC
Sbjct 1238 TGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTC 1277
Score = 34.8 bits (78), Expect = 4.2, Method: Composition-based stats.
Identities = 26/132 (20%), Positives = 42/132 (32%), Gaps = 10/132 (8%)
Query 549 LEIENTSEANNYGTLTKFTLVLYG---TAPEGLPVPPESSGCKTLTSSQACVVCEEGFSL 605
+EI N+ EANN G + G T P G + + C + C++ +
Sbjct 329 MEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTN 388
Query 606 HQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSH 665
+ C G+ ++ + R C C G C SC +
Sbjct 389 NPGGYECGCYAGYRLSADGCGCEDVDECASSRGG----CEHHCTNLAGSF--QC-SCEAG 441
Query 666 ASLDPVEQTCSR 677
L + CS
Sbjct 442 YRLHEDRRGCSP 453
>sp|Q9ULL8|SHRM4_HUMAN Protein Shroom4 OS=Homo sapiens OX=9606
GN=SHROOM4 PE=1 SV=3
Length=1493
Score = 37.5 bits (85), Expect = 0.71, Method: Composition-based stats.
Identities = 21/108 (19%), Positives = 34/108 (31%), Gaps = 13/108 (12%)
Query 571 YGTAPEGLPVPPESSGC---KTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHY 627
Y + P S C K L +S C G + ++C C A Y
Sbjct 844 YHSMSPLQSETPTYSECFASKGLENSMCCKPLHCGDFDYHRTCSYSCSVQGALVHDPCIY 903
Query 628 STENDVETIRASVCAPCHASCATCQGPALTDCLSC------PSHASLD 669
+ + P +C C+ C+ C P H++L+
Sbjct 904 CSGEICPALLKRNMMP---NCYNCRCHH-HQCIRCSVCYHNPQHSALE 947
>sp|P25118|TNR1A_MOUSE Tumor necrosis factor receptor superfamily
member 1A OS=Mus musculus OX=10090 GN=Tnfrsf1a PE=1 SV=1
Length=454
Score = 37.1 bits (84), Expect = 0.72, Method: Composition-based stats.
Identities = 24/110 (22%), Positives = 31/110 (28%), Gaps = 33/110 (30%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVC 641
P+ + +S C C +G L V CP R +VC
Sbjct 45 PQGKYVHSKNNSICCTKCHKGTYL-----VSDCPSPG------------------RDTVC 81
Query 642 APCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQP 691
C T L CLSC TC ++ SP Q
Sbjct 82 RECEKGTFTASQNYLRQCLSCK----------TCRKEMSQVEISPCQADK 121
Score = 35.6 bits (80), Expect = 2.0, Method: Composition-based stats.
Identities = 25/132 (19%), Positives = 37/132 (28%), Gaps = 23/132 (17%)
Query 585 SGCKTLTSSQACVVCEEGFS----------LHQKSCVQHCPPGFAPQVLDTH----YSTE 630
S C + C CE+G L K+C + E
Sbjct 70 SDCPSPGRDTVCRECEKGTFTASQNYLRQCLSCKTCRKEMSQVEISPCQADKDTVCGCKE 129
Query 631 NDVET------IRASVCAPCHASCAT--CQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
N + + C+PC T C+ T C +C + L E + +
Sbjct 130 NQFQRYLSETHFQCVDCSPCFNGTVTIPCKETQNTVC-NCHAGFFLRESECVPCSHCKKN 188
Query 683 RESPPQQQPPRL 694
E PP L
Sbjct 189 EECMKLCLPPPL 200
>sp|P97525|TNR8_RAT Tumor necrosis factor receptor superfamily
member 8 OS=Rattus norvegicus OX=10116 GN=Tnfrsf8 PE=2 SV=2
Length=492
Score = 37.1 bits (84), Expect = 0.72, Method: Composition-based stats.
Identities = 25/113 (22%), Positives = 37/113 (33%), Gaps = 10/113 (9%)
Query 575 PEGLPVPPESSG----CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAP-QVLDTHYST 629
P+ P+ +G + C C G S Q CP G A + +T
Sbjct 20 PKDRPLDTTCTGDLSYYPGEAARNCCYQCPSGLS-----PTQPCPQGPATARSSVILTTT 74
Query 630 ENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
D + C P A C G + C P P +C+R S+ +
Sbjct 75 NEDRKCTACVTCLPGLVEKAPCSGNSPRICECQPGMYCSTPAVNSCARCSEKT 127
>sp|P35556|FBN2_HUMAN Fibrillin-2 OS=Homo sapiens OX=9606 GN=FBN2
PE=1 SV=3
Length=2912
Score = 37.5 bits (85), Expect = 0.72, Method: Composition-based stats.
Identities = 20/104 (19%), Positives = 28/104 (27%), Gaps = 18/104 (17%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVC 641
E G C G+ CP G+ EN+ A
Sbjct 2616 DECDGNHRCQ--HGCQNILGGYRC-------GCPQGYIQHYQWNQCVDENECSNPNAC-- 2664
Query 642 APCHASCATCQGPALTDCLSCPSHASLDPVEQTC--SRQSQSSR 683
A+C + +CPS S D C + SS+
Sbjct 2665 -----GSASCYNTLGSYKCACPSGFSFDQFSSACHDVNECSSSK 2703
>sp|Q9R0B6|LAMC3_MOUSE Laminin subunit gamma-3 OS=Mus musculus
OX=10090 GN=Lamc3 PE=1 SV=2
Length=1581
Score = 37.5 bits (85), Expect = 0.74, Method: Composition-based stats.
Identities = 29/151 (19%), Positives = 41/151 (27%), Gaps = 19/151 (13%)
Query 576 EGLPVPPESSGCKTLTSSQACVVC------EEGFSLHQKSCVQHCPPGFAPQVLD--THY 627
G S G L S + C C H K+ C PG Q D
Sbjct 905 SGRDCSRCSPGFYDLQSGRGCQSCKCHPLGSLENKCHPKTGQCPCRPGVTGQACDRCQLG 964
Query 628 STENDVETIRASVCAPCHASCATCQ---------GPALTDCLSCPSHASLDPVEQTC--S 676
++ R C+P A+ + C G C C + L + C
Sbjct 965 FFGFSIKGCRDCRCSPLGAASSQCHENSTCVCRPGFVGYKCDRCQDNFFLADGDTGCQEC 1024
Query 677 RQSQSSRESPPQQQPPRLPPEVEAGQRLRAG 707
+ + + RL QR G
Sbjct 1025 PTCYALVKEEAAKLKARLMLMEGWLQRSDCG 1055
>sp|Q1W617|SHRM4_MOUSE Protein Shroom4 OS=Mus musculus OX=10090
GN=Shroom4 PE=1 SV=1
Length=1475
Score = 37.1 bits (84), Expect = 0.79, Method: Composition-based stats.
Identities = 19/115 (17%), Positives = 31/115 (27%), Gaps = 3/115 (3%)
Query 579 PVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRA 638
P PE K +S C G + ++C C + + +
Sbjct 846 PTYPECFATKGRDNSLCCKPVHHGDCDYHRTCSHPCSAQGTVRHDPCICCSGEICPALLK 905
Query 639 SVCAPCHASCATCQGPALTDCLSC--PSHASLDPVEQTCSRQSQSSRESPPQQQP 691
P +C C C C S + SR++ Q+ P
Sbjct 906 RNLLPKCHNCR-CHHHQCIRCTGCCHGPQHSAHEDSSMAPGNAWKSRKAAIQEFP 959
>sp|Q9Y6N6|LAMC3_HUMAN Laminin subunit gamma-3 OS=Homo sapiens
OX=9606 GN=LAMC3 PE=1 SV=3
Length=1575
Score = 37.1 bits (84), Expect = 0.83, Method: Composition-based stats.
Identities = 29/145 (20%), Positives = 42/145 (29%), Gaps = 36/145 (25%)
Query 572 GTAPEGLPVPPESSGCK------------------TLTSSQACVVC------EEGFSLHQ 607
G+ E +P P + C L + C C + H
Sbjct 872 GSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHP 931
Query 608 KSCVQHCPPGFAPQVLD--THYSTENDVETIRASVCAPCHASCATCQ---------GPAL 656
K+ C PG Q D ++ RA C+P A+ A C G
Sbjct 932 KTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTCVCRPGFEG 991
Query 657 TDCLSCPSHASLDPVEQTCSRQSQS 681
C C + L + T +Q S
Sbjct 992 YKCDRCHDNFFLTA-DGTHCQQCPS 1015
>sp|Q8VEA6|CRDL2_MOUSE Chordin-like protein 2 OS=Mus musculus
OX=10090 GN=Chrdl2 PE=1 SV=1
Length=426
Score = 36.7 bits (83), Expect = 0.90, Method: Composition-based stats.
Identities = 26/151 (17%), Positives = 42/151 (28%), Gaps = 25/151 (17%)
Query 578 LPVPPESSGCKTLTSSQACVVCEEGFSLHQ-KSCVQHCPPGFAPQVLDTHYSTENDVETI 636
L PP + Q C C + + ++ C +S +
Sbjct 74 LRCPPLHCSQPVMEPQQCCPRCVDPHVPSGLRVPLKSCQLNETTYQHGEIFSAQELFPAR 133
Query 637 RASVCAPC-----HASCA--TCQGPA--------LTDCLSCPSHASLDPVEQTCS----- 676
++ C C H C TC P+ + C +C + E+ +
Sbjct 134 LSNQCVLCSCIEGHTYCGLMTCPEPSCPTTLPLPDSCCQTCKDRTTESSTEENLTQLQHG 193
Query 677 -RQSQSS---RESPPQQQPPRLPPEVEAGQR 703
R SQ R P P L + R
Sbjct 194 ERHSQDPCSERRGPSTPAPTSLSSPLGFIPR 224
>sp|P13388|XMRK_XIPMA Melanoma receptor tyrosine-protein kinase
OS=Xiphophorus maculatus OX=8083 GN=xmrk PE=2 SV=2
Length=1167
Score = 37.1 bits (84), Expect = 0.90, Method: Composition-based stats.
Identities = 17/80 (21%), Positives = 23/80 (29%), Gaps = 9/80 (11%)
Query 583 ESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCA 642
+S C + C+ CP G T + C
Sbjct 565 DSLTCYGPGPANCSKSAH---FQDGPQCIPRCPHGILGD-----GDTLIWKYADKMGQCQ 616
Query 643 PCHASCAT-CQGPALTDCLS 661
PCH +C C GP L+ C
Sbjct 617 PCHQNCTQGCSGPGLSGCRG 636
>sp|Q9GYK2|ITBL_CAEEL Uncharacterized integrin beta-like protein
C05D9.3 OS=Caenorhabditis elegans OX=6239 GN=C05D9.3 PE=1
SV=3
Length=423
Score = 36.3 bits (82), Expect = 0.99, Method: Composition-based stats.
Identities = 27/153 (18%), Positives = 46/153 (30%), Gaps = 11/153 (7%)
Query 582 PESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVC 641
+S G A + L K P + + + T+ C
Sbjct 244 DQSRGGDKCECPLASHGVSKASELEDKCRFNSSSPVCSASGKCKCGQCQCNKPTVTGKFC 303
Query 642 APCHASC------ATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQ----- 690
+ SC C G + DC C + + +CS S + ++
Sbjct 304 QCDNDSCPLAVNGKVCSGNGVCDCGVCKCEMGWERDDCSCSTASNNCVDNGTPAPEEKDK 363
Query 691 PPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCA 723
P +P E EA ++ S L + + S A
Sbjct 364 PESVPEEPEATEKPDDMPSDSDLEKELDESSSA 396
>sp|P60014|KR10A_HUMAN Keratin-associated protein 10-10 OS=Homo
sapiens OX=9606 GN=KRTAP10-10 PE=1 SV=1
Length=251
Score = 35.9 bits (81), Expect = 1.1, Method: Composition-based stats.
Identities = 25/104 (24%), Positives = 33/104 (32%), Gaps = 14/104 (13%)
Query 585 SGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP- 643
S C S A C + S C C + L H +++ C P
Sbjct 154 SVCYVPVCSGASTSCCQQSSCQPACCTASCCRPSSSVSLLCH-------PVCKSTCCVPV 206
Query 644 --CHASCATCQGP--ALTDCLS--CPSHASLDPVEQTCSRQSQS 681
C AS ++CQ C+S C S CS Q S
Sbjct 207 PSCGASASSCQPSCCRTASCVSLLCRPVCSRPACYSLCSGQKSS 250
>sp|P0C6B8|SVEP1_RAT Sushi, von Willebrand factor type A, EGF
and pentraxin domain-containing protein 1 OS=Rattus norvegicus
OX=10116 GN=Svep1 PE=1 SV=1
Length=3564
Score = 36.7 bits (83), Expect = 1.1, Method: Composition-based stats.
Identities = 42/211 (20%), Positives = 64/211 (30%), Gaps = 43/211 (20%)
Query 575 PEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSC-----VQHCPPGFAPQVLDTHYST 629
P+G PP S E GF + + V C PG+ +
Sbjct 3216 PDGTWEPPLSEESCIPVVCGQPESPEHGFVVGSEYSFGSTVVYQCDPGYELEGNRERVCQ 3275
Query 630 ENDVETIRASVCA--PCHASCATCQGPA--------LTDCLSCPSHASLD-PVEQTCSRQ 678
EN + R +VC C A G A + SC +L+ P E C+
Sbjct 3276 ENRQWSGRVAVCRESRCEAPAEFPNGKAVLENTTSGPSLLFSCHRGYTLEGPPEAHCTAN 3335
Query 679 SQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIVLVFVTVFLVLQL 738
S +P + P P V L + +V + ++
Sbjct 3336 GTWSHLAPLCKPNPCPVPFVIPENALLSERE------------------FYVNQNVSIKC 3377
Query 739 RSGFSFRGVKVYTMDRGLISYKGLPPEAWQE 769
R GF +G + T + P E W +
Sbjct 3378 REGFLLKGNGIITCN---------PDETWTQ 3399
>sp|Q6UY66|VGP_MABVO Envelope glycoprotein OS=Lake Victoria marburgvirus
(strain Ozolin-75) OX=482820 GN=GP PE=3 SV=1
Length=681
Score = 36.3 bits (82), Expect = 1.1, Method: Composition-based stats.
Identities = 24/118 (20%), Positives = 38/118 (32%), Gaps = 7/118 (6%)
Query 574 APEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDV 633
P P P+ G T S A + + Q H + H +
Sbjct 297 TPSPQPGTPQQGGNNTNHSQDATTELDNTNTTAQPPTPSHNTTTISTNNTSKHNLSTLSA 356
Query 634 ETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQP 691
+ P S AT + S P A+L P E + +S ++ +SP +P
Sbjct 357 PPQNTT--NPNTQSMAT-----ENEKTSAPPKATLPPTENPTTEKSTNNTKSPTTMEP 407
>sp|P50555|TNR1A_PIG Tumor necrosis factor receptor superfamily
member 1A OS=Sus scrofa OX=9823 GN=TNFRSF1A PE=2 SV=1
Length=461
Score = 36.3 bits (82), Expect = 1.1, Method: Composition-based stats.
Identities = 20/99 (20%), Positives = 23/99 (23%), Gaps = 29/99 (29%)
Query 570 LYGTAPEGLPVPPESSGCKTLTSSQ------ACVVCEEGFSLHQKSCVQHCPPGFAPQVL 623
++G S C S C C +G LH PG
Sbjct 27 VHGLVLHPGDREKRESLCPQGKYSHPQNRSICCTKCHKGTYLHNDC----LGPGLDTD-- 80
Query 624 DTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSC 662
C C T LT CLSC
Sbjct 81 -----------------CRECDNGTFTASENHLTQCLSC 102
>sp|P60411|KR109_HUMAN Keratin-associated protein 10-9 OS=Homo
sapiens OX=9606 GN=KRTAP10-9 PE=1 SV=2
Length=292
Score = 35.9 bits (81), Expect = 1.1, Method: Composition-based stats.
Identities = 22/117 (19%), Positives = 33/117 (28%), Gaps = 9/117 (8%)
Query 572 GTAPEGLPVPPESSGCK--TLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
G P + S C+ TSS C CV C + ++
Sbjct 70 GCTSSCTPSCCQQSSCQPAYCTSSPCQQACCVPVCCKPVCCVPVCCGASSCCQQSSYQPA 129
Query 630 ENDVETIRASVCAP--CHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRE 684
+ + + C P C C C D SC +S + C S +
Sbjct 130 CCASSSCQPACCVPVCCKPVC--CAPTCSEDSYSCCQQSS---CQPACCTSSPCQQS 181
>sp|Q65169|VF602_ASFB7 Protein B602L OS=African swine fever virus
(strain Badajoz 1971 Vero-adapted) OX=10498 GN=Ba71V-079
PE=2 SV=1
Length=602
Score = 36.3 bits (82), Expect = 1.3, Method: Composition-based stats.
Identities = 30/134 (22%), Positives = 47/134 (35%), Gaps = 10/134 (7%)
Query 570 LYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTH--- 626
L+ + + T S+ A S +C C A DT+
Sbjct 153 LHAQSAYTCASTCADTNVDTCASTCASTCASTCASTCASTCASTCASTGASTCADTNVDT 212
Query 627 ---YSTENDVETIRASVCAPCHAS-CA-TCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
+ +V+T AS CA + CA TC + C S + ++D TC+ S
Sbjct 213 CASTCADTNVDTC-ASTCADTNVDTCASTCADTNVNTCASMCADTNVDTCASTCANTCAS 271
Query 682 SRESPPQQQPPRLP 695
+ E P R+P
Sbjct 272 T-EYTDLADPERIP 284
>sp|Q5VY43|PEAR1_HUMAN Platelet endothelial aggregation receptor
1 OS=Homo sapiens OX=9606 GN=PEAR1 PE=1 SV=1
Length=1037
Score = 36.3 bits (82), Expect = 1.4, Method: Composition-based stats.
Identities = 24/125 (19%), Positives = 32/125 (26%), Gaps = 13/125 (10%)
Query 574 APEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDV 633
P S G + ++ V C L +C+Q C PG+
Sbjct 139 MWGPQCDKPCSCGNNSSCDPKSGV-CSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGA- 196
Query 634 ETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTC--SRQSQSSRESPPQQQP 691
PC C PA SC S C + Q+ Q
Sbjct 197 ---------PCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGS 247
Query 692 PRLPP 696
PP
Sbjct 248 CSCPP 252
>sp|Q9H324|ATS10_HUMAN A disintegrin and metalloproteinase with
thrombospondin motifs 10 OS=Homo sapiens OX=9606 GN=ADAMTS10
PE=1 SV=2
Length=1103
Score = 36.3 bits (82), Expect = 1.4, Method: Composition-based stats.
Identities = 22/119 (18%), Positives = 32/119 (27%), Gaps = 16/119 (13%)
Query 577 GLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETI 636
P PP C E +L C C PG +V+ + T+
Sbjct 929 PQPRPPVLEAC------HGPTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRA--TL 980
Query 637 RASVCAPCHASCAT--CQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPR 693
+ C+P AT C CP + CS Q + +
Sbjct 981 PPAHCSPAAKPPATMRCNLRR------CPPARWVAGEWGECSAQCGVGQRQRSVRCTSH 1033
>sp|P0DTN0|CRMB_MONPV Soluble TNF receptor II OS=Monkeypox virus
OX=10244 GN=OPG002 PE=3 SV=1
Length=349
Score = 35.9 bits (81), Expect = 1.5, Method: Composition-based stats.
Identities = 18/83 (22%), Positives = 28/83 (34%), Gaps = 9/83 (11%)
Query 599 CEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTD 658
C++ + C CPPG L ++ + C PC + T L
Sbjct 32 CKDNEYRSRNLCCLSCPPGTYASRL---------CDSKTNTQCTPCGSDTFTSHNNHLQA 82
Query 659 CLSCPSHASLDPVEQTCSRQSQS 681
CLSC + VE + +
Sbjct 83 CLSCNGRCDSNQVETRSCNTTHN 105
>sp|A8XMW6|CED1_CAEBR Cell death abnormality protein 1 OS=Caenorhabditis
briggsae OX=6238 GN=ced-1 PE=3 SV=2
Length=1134
Score = 36.3 bits (82), Expect = 1.5, Method: Composition-based stats.
Identities = 18/85 (21%), Positives = 28/85 (33%), Gaps = 6/85 (7%)
Query 595 ACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGP 654
+C + S C+ CP G + D + CA+ P
Sbjct 602 SCDCSDSYCSRQTGKCI--CPLGKKGTLCDQPCEANTYGP---QCQLTTTPSQCAS-TDP 655
Query 655 ALTDCLSCPSHASLDPVEQTCSRQS 679
CL+CP +S EQ C + +
Sbjct 656 RNGVCLTCPPGSSGHQCEQNCPQGT 680
>sp|A2A5X4|KR291_MOUSE Keratin-associated protein 29-1 OS=Mus
musculus OX=10090 GN=Krtap29-1 PE=3 SV=1
Length=342
Score = 35.6 bits (80), Expect = 1.9, Method: Composition-based stats.
Identities = 30/158 (19%), Positives = 47/158 (30%), Gaps = 13/158 (8%)
Query 551 IENTSEANNYGTLTKFTLVLYG---TAPEGLPVPPESSGCKT---LTSSQACVVCEEGFS 604
I N + + LV + P+ +PV E C + + +C +
Sbjct 28 IRNAIRLPSSCRCRTWQLVTHQENRQGPDSVPVSSEPVSCPSTCFPETPCVGFIC-QPIG 86
Query 605 LHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLS-CP 663
H C P E+ + CH S C + C
Sbjct 87 SHMACCASDTGGSPHPAASCQPSCLESAGCHTMCYENSSCHQSSGQGSACTSGSCQTACG 146
Query 664 SHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAG 701
AS D +++C E+ + P LP EAG
Sbjct 147 PSASCD--DRSCQPSCS---EATSYAETPCLPAGCEAG 179
>sp|P15636|API_ACHLY Protease 1 OS=Achromobacter lyticus OX=224
PE=1 SV=1
Length=653
Score = 35.6 bits (80), Expect = 2.0, Method: Composition-based stats.
Identities = 17/89 (19%), Positives = 27/89 (30%), Gaps = 3/89 (3%)
Query 428 LLDAGAMVALAQNWTTVAPQRKCIIDILTEPKDIGKRLEVRKTVTACLGEPNHITRLEHA 487
+ D G TV+ I V +T N
Sbjct 537 VTDNGGATNTKTGSVTVSGGPGAQTYTNDTDVAIPDNATVESPITVSGRTGNGSATTP-- 594
Query 488 QARLTLSYNRRGDLAIHLVSPMGTRSTLL 516
++T+ + + DL + LV+P GT L
Sbjct 595 -IQVTIYHTYKSDLKVDLVAPDGTVYNLH 622
>sp|P35590|TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Homo
sapiens OX=9606 GN=TIE1 PE=1 SV=1
Length=1138
Score = 35.9 bits (81), Expect = 2.1, Method: Composition-based stats.
Identities = 30/158 (19%), Positives = 46/158 (29%), Gaps = 17/158 (11%)
Query 539 WDEDPSGEWVLEIENTSEANNYGTLTKFTLVL--YGTAPEGLPVPPESSGCKTLTSSQAC 596
W E G ++L++ N + + G + L G+A L V +G ++ C
Sbjct 170 WHEAQDGRFLLQLPNV-QPPSSGIYSATYLEASPLGSAFFRLIVRGCGAGRWGPGCTKEC 228
Query 597 VVCEEGFSLHQKSCVQHCPPGFAPQV-----------LDTHYSTENDVETIRASVCAPCH 645
C G H CPPGF + C P
Sbjct 229 PGCLHGGVCHDHDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGISGCRGLTFCLPDP 288
Query 646 ASCATCQGPALTDCL-SCPSHASLDPVEQTCSRQSQSS 682
C+ G + C +C C Q Q+
Sbjct 289 YGCSCGSGWRGSQCQEACAPGHFGADCRLQC--QCQNG 324
>sp|P98167|SSPO_BOVIN SCO-spondin OS=Bos taurus OX=9913 GN=SSPO
PE=2 SV=2
Length=5146
Score = 35.9 bits (81), Expect = 2.2, Method: Composition-based stats.
Identities = 25/126 (20%), Positives = 40/126 (32%), Gaps = 17/126 (13%)
Query 580 VPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQ---HCPPGFAPQVLDTHYSTE-NDVET 635
P C+ + G + C P G + + H + T
Sbjct 4840 TPCMQEPCQLGCDCPRGQLLHNGTCVPPAECPCTQLSLPWGLTLTLEEQHRELPPGTLLT 4899
Query 636 IRASVCAPCHASCATCQGPALTDCLSCPSHAS--------LDPVEQTC-SRQSQSSRESP 686
+ C C +C +LTDC CP + L P EQTC + ++ +
Sbjct 4900 QNCTHCI-CQGGAFSC---SLTDCQECPPGETWQQVAPGELGPCEQTCREPNATETQGNC 4955
Query 687 PQQQPP 692
+Q P
Sbjct 4956 SGRQAP 4961
Score = 34.8 bits (78), Expect = 4.2, Method: Composition-based stats.
Identities = 23/139 (17%), Positives = 29/139 (21%), Gaps = 4/139 (3%)
Query 581 PPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASV 640
S C CE + CP + YS
Sbjct 3253 RSRSRACDQPPPQGLGDYCEGPRAQGAACQALPCPVTNCTAIEGAEYSACGPPCPRSCDD 3312
Query 641 CAPCHASCAT-CQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVE 699
C C C P LS + P +C R P Q
Sbjct 3313 LVHCVWHCQPGCYCP-PGQVLSADGTVHVQPGHCSCLDLLTGERHRPGAQLAKPDGCNYC 3371
Query 700 A--GQRLRAGLLPSHLPEV 716
+L LP +P
Sbjct 3372 TCSEGQLTCTDLPCPVPGA 3390
>sp|Q06805|TIE1_BOVIN Tyrosine-protein kinase receptor Tie-1 OS=Bos
taurus OX=9913 GN=TIE1 PE=2 SV=1
Length=1136
Score = 35.6 bits (80), Expect = 2.2, Method: Composition-based stats.
Identities = 18/99 (18%), Positives = 24/99 (24%), Gaps = 14/99 (14%)
Query 596 CVVCEEGFSLHQKSCVQHCPPGFAPQV-----------LDTHYSTENDVETIRASVCAPC 644
C C G H + CPPGF + C P
Sbjct 226 CPGCLHGGVCHDQDGECVCPPGFTGTRCEQACREGRFGQSCQEQCPGTSGCRGLTFCLPD 285
Query 645 HASCATCQGPALTDCL-SCPSHASLDPVEQTCSRQSQSS 682
C+ G + C +C C Q Q+
Sbjct 286 PYGCSCGSGWRGSQCQEACAPGRFGADCHLQC--QCQNG 322
>sp|Q61292|LAMB2_MOUSE Laminin subunit beta-2 OS=Mus musculus
OX=10090 GN=Lamb2 PE=1 SV=2
Length=1799
Score = 35.6 bits (80), Expect = 2.3, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 29/97 (30%), Gaps = 6/97 (6%)
Query 586 GCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCH 645
C L + C H CP Q L+ + N C PC
Sbjct 1040 TCNLLGTDPR--RCPSTDLCHCDPSTGQCPCLPHVQGLNCDHCAPNFWNFTSGRGCQPCA 1097
Query 646 ASCATCQGPALTDCLS-CPSHASLDPVEQTCSRQSQS 681
+ +GP + C HA +TCS + Q
Sbjct 1098 CHPSRARGPTCNEFTGQCHCHAGFGG--RTCS-ECQE 1131
>sp|P36941|TNR3_HUMAN Tumor necrosis factor receptor superfamily
member 3 OS=Homo sapiens OX=9606 GN=LTBR PE=1 SV=1
Length=435
Score = 35.2 bits (79), Expect = 2.4, Method: Composition-based stats.
Identities = 30/126 (24%), Positives = 46/126 (37%), Gaps = 18/126 (14%)
Query 568 LVLYG--TAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDT 625
L L+G A + VPP +S +T + +E + + C CPPG
Sbjct 19 LGLFGLLAASQPQAVPPYASENQTCRDQE-----KEYYEPQHRICCSRCPPGTYVSA--- 70
Query 626 HYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRES 685
IR +VCA C + LT C C + +E+ S R++
Sbjct 71 ------KCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEE--IAPCTSKRKT 122
Query 686 PPQQQP 691
+ QP
Sbjct 123 QCRCQP 128
>sp|Q6NYJ3|TE2IP_DANRE Telomeric repeat-binding factor 2-interacting
protein 1 OS=Danio rerio OX=7955 GN=terf2ip PE=2 SV=2
Length=616
Score = 35.6 bits (80), Expect = 2.4, Method: Composition-based stats.
Identities = 26/195 (13%), Positives = 55/195 (28%), Gaps = 21/195 (11%)
Query 573 TAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEND 632
T+ G P+ + + C Q + P +L D
Sbjct 378 TSDSGNPIGDQG-----CDNPHGCNANSSPSKTRQTNSEASTPDSKKLGILAKAAKEFED 432
Query 633 VETIRASVCAPCHASCAT-CQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQP 691
+ + S C C P+ S + E ++ +SP ++
Sbjct 433 SDVMDDSE--ECENPCEVPIAEPSDAQESSATPATLVREPESQAEHHEETQPDSPMSEEE 490
Query 692 PRLPPEVEAGQRLRAGLLPSHLPEV-VAGLSCAFIVLVFVTVFLVLQ------------L 738
P L + SH+ E LS + + + L+ + L
Sbjct 491 RPGPSSAVVPPSLNSSTSCSHIRETPEETLSRDLLEVKEQVINLMRETKKDLVEVTKALL 550
Query 739 RSGFSFRGVKVYTMD 753
++ + +V+ ++
Sbjct 551 KASGDLKRAQVFLLN 565
>sp|Q9H8U3|ZFAN3_HUMAN AN1-type zinc finger protein 3 OS=Homo
sapiens OX=9606 GN=ZFAND3 PE=1 SV=1
Length=227
Score = 34.8 bits (78), Expect = 2.5, Method: Composition-based stats.
Identities = 27/145 (19%), Positives = 49/145 (34%), Gaps = 10/145 (7%)
Query 572 GTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEN 631
G+ P P C SS+ +C + F+ QK +S E
Sbjct 5 GSERSKAPSLPPRCPCGFWGSSKTMNLCSKCFADFQKKQPDDDSAPSTSNSQSDLFSEET 64
Query 632 DVETIRASVCAPCHASCA-------TCQGPALTDCLSCPSHASLDPV---EQTCSRQSQS 681
+ S+ P + P+ +C C A + + +++C SQS
Sbjct 65 TSDNNNTSITTPTLSPSQQPLPTELNVTSPSKEECGPCTDTAHVSLITPTKRSCGTDSQS 124
Query 682 SRESPPQQQPPRLPPEVEAGQRLRA 706
E+ P ++P L + + R+
Sbjct 125 ENEASPVKRPRLLENTERSEETSRS 149
>sp|A8MXZ3|KRA91_HUMAN Keratin-associated protein 9-1 OS=Homo
sapiens OX=9606 GN=KRTAP9-1 PE=3 SV=1
Length=250
Score = 34.8 bits (78), Expect = 2.5, Method: Composition-based stats.
Identities = 21/96 (22%), Positives = 29/96 (30%), Gaps = 7/96 (7%)
Query 588 KTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP--CH 645
T ++ + C + C C P +T T T AS C P C
Sbjct 26 PTTVTTCSSTPCCQPSCCVPSCCQPCCHP---TCCQNTCCRTTCCQPTCVASCCQPSCCS 82
Query 646 ASC--ATCQGPALTDCLSCPSHASLDPVEQTCSRQS 679
C TC G + SC S +C +
Sbjct 83 TPCCQPTCCGSSCCGQTSCGSSCCQPICGSSCCQPC 118
>sp|Q93038|TNR25_HUMAN Tumor necrosis factor receptor superfamily
member 25 OS=Homo sapiens OX=9606 GN=TNFRSF25 PE=1 SV=2
Length=417
Score = 35.2 bits (79), Expect = 2.5, Method: Composition-based stats.
Identities = 17/106 (16%), Positives = 28/106 (26%), Gaps = 3/106 (3%)
Query 574 APEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDV 633
A E E + C+ + V E ++ C C PG+ + + + +
Sbjct 80 AWENH-HNSECARCQACDEQASQVALENCSAVADTRC--GCKPGWFVECQVSQCVSSSPF 136
Query 634 ETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS 679
C H TDC +C S
Sbjct 137 YCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTS 182
>sp|Q700K0|SSPO_RAT SCO-spondin OS=Rattus norvegicus OX=10116
GN=Sspo PE=2 SV=1
Length=5141
Score = 35.6 bits (80), Expect = 2.6, Method: Composition-based stats.
Identities = 24/114 (21%), Positives = 37/114 (32%), Gaps = 11/114 (10%)
Query 591 TSSQACVVCEEGFSLHQKSCVQH--CPPGFAPQVLDTHYSTENDVETIRASVCAPCHASC 648
Q C G LH +C+ CP E + + + + +
Sbjct 4843 EPCQLGCGCPGGQLLHSGTCIPPEACPCTRLSLPWGLTLPLEEQAQELPSGTVLTWNCTH 4902
Query 649 ATCQGP----ALTDCLSCPSHAS-----LDPVEQTCSRQSQSSRESPPQQQPPR 693
TCQG + TDC CP L P E+TC +++ S +
Sbjct 4903 CTCQGGVFTCSHTDCQECPPGEILQLGELRPCEKTCLEMNKTQAWSNCTEAQVP 4956
>sp|Q5U2M7|ZFAN3_RAT AN1-type zinc finger protein 3 OS=Rattus
norvegicus OX=10116 GN=Zfand3 PE=2 SV=1
Length=227
Score = 34.8 bits (78), Expect = 2.6, Method: Composition-based stats.
Identities = 26/134 (19%), Positives = 45/134 (34%), Gaps = 10/134 (7%)
Query 572 GTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEN 631
G+ P P C SS+ +C + F+ QK +S E
Sbjct 5 GSERSKAPSLPPRCPCGFWGSSKTMNLCSKCFADFQKKQPDDDSTPSTSNSQSDLFSEET 64
Query 632 DVETIRASVCAPCHASCA-------TCQGPALTDCLSCPSHASLDPV---EQTCSRQSQS 681
+ SV P + P+ +C C A + + +++C SQS
Sbjct 65 TSDNNNTSVTTPTLSPSQQSLPTELNVTSPSEEECGPCTDTAHVSLITPTKRSCGADSQS 124
Query 682 SRESPPQQQPPRLP 695
E+ P ++P +
Sbjct 125 ESEASPVKRPRLVE 138
>sp|Q5KSL6|DGKK_HUMAN Diacylglycerol kinase kappa OS=Homo sapiens
OX=9606 GN=DGKK PE=1 SV=1
Length=1271
Score = 35.6 bits (80), Expect = 2.7, Method: Composition-based stats.
Identities = 18/61 (30%), Positives = 24/61 (39%), Gaps = 3/61 (5%)
Query 637 RASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQS--QSSRESPPQQQPPRL 694
+S CA CH SC + Q CL C S D + S++ +S R S
Sbjct 408 VSSQCAVCHESCGSYQRLQDFRCLWCNSTVH-DDCRRRFSKECCFRSHRSSVIPPTALSD 466
Query 695 P 695
P
Sbjct 467 P 467
>sp|Q3V2C1|KRA93_MOUSE Keratin-associated protein 9-3 OS=Mus musculus
OX=10090 GN=Krtap9-3 PE=2 SV=1
Length=136
Score = 33.6 bits (75), Expect = 2.8, Method: Composition-based stats.
Identities = 20/105 (19%), Positives = 28/105 (27%), Gaps = 7/105 (7%)
Query 586 GCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAP-- 643
C T SS C + C C + C
Sbjct 13 TCSTGGSSCCQPTCTQSSCCQPSCCEASCCQPSCCETGFGGGIGCGQEGGSGGVSCRVRW 72
Query 644 CHASCATCQGPALTDC--LSC--PSHASLDPVEQTCSRQSQSSRE 684
C C +G L C +SC P+ L + +C R S +
Sbjct 73 CRPDCR-VEGTCLPPCCVVSCTPPTCCQLHHAQASCCRPSYCGQS 116
>sp|Q24SS4|DNAJ_DESHY Chaperone protein DnaJ OS=Desulfitobacterium
hafniense (strain Y51) OX=138119 GN=dnaJ PE=3 SV=1
Length=377
Score = 34.8 bits (78), Expect = 2.8, Method: Composition-based stats.
Identities = 20/108 (19%), Positives = 35/108 (32%), Gaps = 7/108 (6%)
Query 623 LDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
+ + TE +++ R C CH + G T C C + ++T Q++
Sbjct 126 EEAAFGTEKEIQVPRQETCTECH-GSGSAPGTHPTTCSQCHGTGQVKATQRTPFGAIQTA 184
Query 683 RESPPQQ------QPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCAF 724
R P P + R + + P GL+ F
Sbjct 185 RTCPACNGSGQFISSPCKECSGKGTTRKVKTIKVTVPPGSEDGLNLRF 232
>sp|B8FUN3|DNAJ_DESHD Chaperone protein DnaJ OS=Desulfitobacterium
hafniense (strain DSM 10664 / DCB-2) OX=272564 GN=dnaJ
PE=3 SV=1
Length=377
Score = 34.8 bits (78), Expect = 2.8, Method: Composition-based stats.
Identities = 20/108 (19%), Positives = 35/108 (32%), Gaps = 7/108 (6%)
Query 623 LDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSS 682
+ + TE +++ R C CH + G T C C + ++T Q++
Sbjct 126 EEAAFGTEKEIQVPRQETCTECH-GSGSAPGTHPTTCSQCHGTGQVKATQRTPFGAIQTA 184
Query 683 RESPPQQ------QPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCAF 724
R P P + R + + P GL+ F
Sbjct 185 RTCPACNGSGQFISSPCKECSGKGTTRKVKTIKVTVPPGSEDGLNLRF 232
>sp|Q3UHD1|AGRB1_MOUSE Adhesion G protein-coupled receptor B1
OS=Mus musculus OX=10090 GN=Adgrb1 PE=1 SV=1
Length=1582
Score = 35.2 bits (79), Expect = 3.4, Method: Composition-based stats.
Identities = 21/110 (19%), Positives = 33/110 (30%), Gaps = 9/110 (8%)
Query 561 GTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAP 620
G +++ + T + + S C+ + + +Q CP
Sbjct 468 GNWNEWS--SWSTCSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPVDGKW 525
Query 621 QVLDTHYS---TENDVETIRASVCAPCHASCATCQGPALT--DC--LSCP 663
Q + S T R VC+ A CQGP C CP
Sbjct 526 QAWASWGSCSVTCGGGSQRRERVCSGPFFGGAACQGPQDEYRQCGAQRCP 575
>sp|Q24025|SOG_DROME Dorsal-ventral patterning protein Sog OS=Drosophila
melanogaster OX=7227 GN=sog PE=1 SV=1
Length=1038
Score = 35.2 bits (79), Expect = 3.4, Method: Composition-based stats.
Identities = 27/177 (15%), Positives = 45/177 (25%), Gaps = 32/177 (18%)
Query 584 SSGCKTLT-SSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASV-- 640
S C+ + + C E+ + C P A N + ++
Sbjct 773 QSSCEVIKCPALKCKSTEQLLQRDGECCPSCVPKKEAADYSAQSSPATNATDLLQQRRGC 832
Query 641 ------------------------CAPCHASCATCQGPALT-DC--LSCPSHASLDPVEQ 673
C C T + C L C + P ++
Sbjct 833 RLGEQFHPAGASWHPFLPPNGFDTCTTCSCDPLTLEIRCPRLVCPPLQCSEKLAYRPDKK 892
Query 674 TCSRQSQSSRESPPQQQPPRLPPEVEAGQRLRAGLLPSH-LPEVVAGLSCAFIVLVF 729
C + ++S P Q PSH EV+A C + V+
Sbjct 893 ACCKICPEGKQSSSNGHKTT-PNNPNVLQDQAMQRSPSHSAEEVLANGGCKVVNKVY 948
>sp|C0HL12|AGRB1_RAT Adhesion G protein-coupled receptor B1 OS=Rattus
norvegicus OX=10116 GN=Adgrb1 PE=1 SV=1
Length=1577
Score = 35.2 bits (79), Expect = 3.4, Method: Composition-based stats.
Identities = 21/110 (19%), Positives = 33/110 (30%), Gaps = 9/110 (8%)
Query 561 GTLTKFTLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAP 620
G +++ + T + + S C+ + + +Q CP
Sbjct 464 GNWNEWS--SWSTCSASCSQGRQQRTRECNGPSYGGAECQGHWVETRDCFLQQCPVDGKW 521
Query 621 QVLDTHYS---TENDVETIRASVCAPCHASCATCQGPALT--DC--LSCP 663
Q + S T R VC+ A CQGP C CP
Sbjct 522 QAWASWGSCSVTCGGGSQRRERVCSGPFFGGAACQGPQDEYRQCGAQRCP 571
>sp|Q66J85|ZFAN3_XENLA AN1-type zinc finger protein 3 homolog
OS=Xenopus laevis OX=8355 GN=zfand3 PE=2 SV=1
Length=226
Score = 34.0 bits (76), Expect = 3.5, Method: Composition-based stats.
Identities = 26/130 (20%), Positives = 45/130 (35%), Gaps = 9/130 (7%)
Query 572 GTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEN 631
G+ P P C SS+ +C + F+ QK + +E
Sbjct 5 GSERSNAPSLPPRCPCGFWGSSKTMNLCSKCFADFQKKQPDEDTAPSTSSSQSDLFPSET 64
Query 632 DVETIRASVCAPC------HASCATCQGPALTDCLSCPSHASLD---PVEQTCSRQSQSS 682
D + S+ P + P+ DC C A + P +++C SQS
Sbjct 65 DSDNGNTSIPTPTVNPTQQLPTELNVDSPSKEDCGPCTDSAHVSLTTPSKRSCDSDSQSE 124
Query 683 RESPPQQQPP 692
++ P ++P
Sbjct 125 DDTSPMKRPR 134
>sp|Q197F5|005L_IIV3 Uncharacterized protein 005L OS=Invertebrate
iridescent virus 3 OX=345201 GN=IIV3-005L PE=3 SV=1
Length=217
Score = 34.0 bits (76), Expect = 3.5, Method: Composition-based stats.
Identities = 30/163 (18%), Positives = 39/163 (24%), Gaps = 29/163 (18%)
Query 572 GTAPEGLPVPP------------ESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFA 619
G +P P P S C +S E+ + C
Sbjct 24 GQSPYPYPGMPCNSSRQCGLGTCVHSRCAHCSSDGTLCSPEDPTMVWPCCPESSCQLVVG 83
Query 620 PQVLDTHYSTENDVET------------IRASVCAPCHASCATCQGP-----ALTDCLSC 662
L HY+ + T R S C C A C P +C S
Sbjct 84 LPSLVNHYNCLPNQCTDSSQCPGGFGCMTRRSKCELCKADGEACNSPYLDWRKDKECCSG 143
Query 663 PSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRLR 705
H +E C + Q PP LR
Sbjct 144 YCHTEARGLEGVCIDPKKIFCTPKNPWQLAPYPPSYHQPTTLR 186
>sp|Q8BH27|MEGF9_MOUSE Multiple epidermal growth factor-like domains
protein 9 OS=Mus musculus OX=10090 GN=Megf9 PE=2 SV=1
Length=600
Score = 34.8 bits (78), Expect = 3.6, Method: Composition-based stats.
Identities = 21/104 (20%), Positives = 27/104 (26%), Gaps = 9/104 (9%)
Query 579 PVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQ---HCPPGFAPQVLDTHYSTENDVET 635
P P + + C E G L K C Q C Q L E
Sbjct 185 PTAPVTEAPTSPPPEHMCNCSEVGS-LDVKRCNQTTGQCDCHVGYQGLHCDTCKEGFYLN 243
Query 636 IRASVCAPCH-----ASCATCQGPALTDCLSCPSHASLDPVEQT 674
+C PCH A C C + + D +
Sbjct 244 HTVGLCLPCHCSPHGAVSILCNSSGNCQCKVGVTGSMCDKCQDG 287
>sp|P60412|KR10B_HUMAN Keratin-associated protein 10-11 OS=Homo
sapiens OX=9606 GN=KRTAP10-11 PE=1 SV=3
Length=298
Score = 34.4 bits (77), Expect = 3.7, Method: Composition-based stats.
Identities = 20/95 (21%), Positives = 32/95 (34%), Gaps = 1/95 (1%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C + S + C++ C C + L H + +S CAP +
Sbjct 204 CVPVCSRASSSRCQQPS-CQPACCTTSCCRPSSSVSLLCHPVCRSTCCVPVSSCCAPTSS 262
Query 647 SCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQS 681
++C PA L C +S CS + S
Sbjct 263 CQSSCCRPASCVSLLCRPASSRLACYSLCSGKKSS 297
>sp|P14328|SP96_DICDI Spore coat protein SP96 OS=Dictyostelium
discoideum OX=44689 GN=cotA PE=4 SV=2
Length=600
Score = 34.8 bits (78), Expect = 3.8, Method: Composition-based stats.
Identities = 20/92 (22%), Positives = 27/92 (29%), Gaps = 15/92 (16%)
Query 609 SCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCATCQGPALTDCLSCPSHASL 668
CP GF QV +VC P +S + D + CP S
Sbjct 185 CSNTQCPNGFYCQVQG------------NNAVCVPQQSSTSGGHQNDPCDTVQCPYGYSC 232
Query 669 ---DPVEQTCSRQSQSSRESPPQQQPPRLPPE 697
D E C+R P + P +
Sbjct 233 ESRDGFEAKCTRDEDEPTHRPTHRPKPPHDSD 264
>sp|Q6IEK5|WRK76_ORYSI WRKY transcription factor WRKY76 OS=Oryza
sativa subsp. indica OX=39946 GN=WRKY76 PE=2 SV=1
Length=327
Score = 34.4 bits (77), Expect = 3.8, Method: Composition-based stats.
Identities = 27/170 (16%), Positives = 46/170 (27%), Gaps = 20/170 (12%)
Query 567 TLVLYGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTH 626
L L G+A PV P S ++ S + C+ + HQ G A
Sbjct 87 RLGLDGSASPPRPVSPLSGKKRSRESMETANSCDANSNRHQG--------GDADHAESFA 138
Query 627 YSTENDVETIRASVCAPCHASCATC------QGPALTDCLSCPSHASLDPVEQTCSRQSQ 680
+ VC S + Q ++ + + +
Sbjct 139 ADDGTCRRIKVSRVCRRIDPSDTSLVVKDGYQWRKYGQKVTRDNPSPRAYFRCAFAPSCP 198
Query 681 SSRE-SPPQQQPPRLPPEVEAG-----QRLRAGLLPSHLPEVVAGLSCAF 724
++ + L E RAG LP+ + L C+
Sbjct 199 VKKKVQRSAEDSSLLVATYEGEHNHPHPSPRAGELPAAVGGAGGSLPCSI 248
>sp|Q497H0|ZFAN3_MOUSE AN1-type zinc finger protein 3 OS=Mus musculus
OX=10090 GN=Zfand3 PE=2 SV=1
Length=227
Score = 34.0 bits (76), Expect = 3.9, Method: Composition-based stats.
Identities = 26/134 (19%), Positives = 45/134 (34%), Gaps = 10/134 (7%)
Query 572 GTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTEN 631
G+ P P C SS+ +C + F+ QK +S E
Sbjct 5 GSERSKAPSLPPRCPCGFWGSSKTMNLCSKCFADFQKKQPDDDSTPSTSNSQSDLFSEET 64
Query 632 DVETIRASVCAPCHASCA-------TCQGPALTDCLSCPSHASLDPV---EQTCSRQSQS 681
+ SV P + P+ +C C A + + +++C SQS
Sbjct 65 TSDNNNTSVTTPTLSPSQQSLPTELNVTSPSTEECGPCTDTAHVSLITPTKRSCGADSQS 124
Query 682 SRESPPQQQPPRLP 695
E+ P ++P +
Sbjct 125 ENEASPVKRPRLVE 138
>sp|P97677|DLL1_RAT Delta-like protein 1 OS=Rattus norvegicus
OX=10116 GN=Dll1 PE=1 SV=1
Length=714
Score = 34.8 bits (78), Expect = 4.4, Method: Composition-based stats.
Identities = 18/89 (20%), Positives = 28/89 (31%), Gaps = 9/89 (10%)
Query 590 LTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHASCA 649
+ +C E+ +S CPPGF +V + T D C+
Sbjct 336 CRNGGSCTDLEDSYSCT-------CPPGFYGKVCELSAMTCADGPCFNGGRCSDNPDGGY 388
Query 650 TCQGPALTDCLSCPSHASLDPVEQTCSRQ 678
TC PA +C +D +
Sbjct 389 TCHCPAGFSGFNCEKK--IDLCSSSPCSN 415
>sp|P60409|KR107_HUMAN Keratin-associated protein 10-7 OS=Homo
sapiens OX=9606 GN=KRTAP10-7 PE=1 SV=3
Length=370
Score = 34.0 bits (76), Expect = 4.9, Method: Composition-based stats.
Identities = 21/99 (21%), Positives = 28/99 (28%), Gaps = 4/99 (4%)
Query 587 CKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCHA 646
C S A C + S C C + L S CAP +
Sbjct 275 CCVPVCSGASTSCCQQSSCQPACCTTSCCRPSSSVSLLCRPVCRPACCVPVPSCCAPTSS 334
Query 647 SCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRES 685
A+C PA L C S C + + + S
Sbjct 335 CQASCCRPASCVSLLCRPACS----RPACCGPTSTQKSS 369
Score = 33.6 bits (75), Expect = 8.3, Method: Composition-based stats.
Identities = 25/116 (22%), Positives = 32/116 (28%), Gaps = 12/116 (10%)
Query 572 GTAPEGLPVPPESSGCK--TLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYST 629
G P + S CK TSS C CV C ++
Sbjct 199 GCISSCTPSCCQQSSCKPACCTSSPCQQACCVPVCCKPVCCVPTCSDDSGSCCQPACCTS 258
Query 630 ENDVETIRASVCAPCHASC--ATCQGPALTDCL--SCPSHASLDPVEQTCSRQSQS 681
+ VC C C C G + + C SC +C R S S
Sbjct 259 SQSQQGCCVPVC--CKPVCCVPVCSGASTSCCQQSSCQPAC----CTTSCCRPSSS 308
>sp|Q8WXS8|ATS14_HUMAN A disintegrin and metalloproteinase with
thrombospondin motifs 14 OS=Homo sapiens OX=9606 GN=ADAMTS14
PE=2 SV=2
Length=1223
Score = 34.4 bits (77), Expect = 5.1, Method: Composition-based stats.
Identities = 19/126 (15%), Positives = 31/126 (25%), Gaps = 6/126 (5%)
Query 576 EGLPVPPESSGCKTLTSSQACVVCEEGF-SLHQKSCVQHCPPGFAPQVLDTHYSTENDVE 634
P PPE G Q G+ + + C + + ++
Sbjct 463 PAWPQPPELPGINYSMDEQCRFDFGSGYQTCLAFRTFEPCKQLWCSHPDNPYFCKTKKGP 522
Query 635 TIRASVCAP---CHASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRESPPQQQP 691
+ + CAP C C + S +CSR S +
Sbjct 523 PLDGTECAPGKWCFKG--HCIWKSPEQTYGQDGGWSSWTKFGSCSRSCGGGVRSRSRSCN 580
Query 692 PRLPPE 697
P
Sbjct 581 NPSPAY 586
>sp|P43489|TNR4_HUMAN Tumor necrosis factor receptor superfamily
member 4 OS=Homo sapiens OX=9606 GN=TNFRSF4 PE=1 SV=1
Length=277
Score = 34.0 bits (76), Expect = 5.4, Method: Composition-based stats.
Identities = 25/151 (17%), Positives = 39/151 (26%), Gaps = 19/151 (13%)
Query 584 SSGCKTLTSSQACVVCEEGFSLHQKSCVQ------HCPPGFAPQVLDTHYSTENDVETIR 637
G ++ + C C G + + C PGF V+ + +R
Sbjct 31 CVGDTYPSNDRCCHECRPGNGMVSRCSRSQNTVCRPCGPGFYNDVVSSKPCKPCTWCNLR 90
Query 638 ASVCAP--CHASCAT-CQGPALTD----------CLSCPSHASLDPVEQTCSRQSQSSRE 684
+ C A+ T C+ A T C CP Q C + +
Sbjct 91 SGSERKQLCTATQDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLA 150
Query 685 SPPQQQPPRLPPEVEAGQRLRAGLLPSHLPE 715
QP + R P
Sbjct 151 GKHTLQPASNSSDAICEDRDPPATQPQETQG 181
>sp|P15800|LAMB2_RAT Laminin subunit beta-2 OS=Rattus norvegicus
OX=10116 GN=Lamb2 PE=1 SV=1
Length=1801
Score = 34.4 bits (77), Expect = 5.8, Method: Composition-based stats.
Identities = 31/158 (20%), Positives = 42/158 (27%), Gaps = 10/158 (6%)
Query 586 GCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASVCAPCH 645
C L + C H CP Q L N C PC
Sbjct 1042 TCNLLGTD--PQRCPSTDLCHCDPSTGQCPCLPHVQGLSCDRCAPNFWNFTSGRGCQPCA 1099
Query 646 ASCATCQGPALTDCLS-CPSHASLDPVEQTCSRQSQSSRESPPQQQPPRLPPEVEAGQRL 704
+ +GP + C HA +TCS + Q P Q + +
Sbjct 1100 CHPSRARGPTCNEFTGQCHCHAGFGG--RTCS-ECQELHWGDPGLQCRACDCDPRGIDKP 1156
Query 705 RAGLLPSHL---PEVVAGLSCAFIVLVFVTVFLVLQLR 739
+ H P V +G+ C F VF
Sbjct 1157 QCHRSTGHCSCRPGV-SGVRCDQCARGFSGVFPACHPC 1193
>sp|O43593|HAIR_HUMAN Lysine-specific demethylase hairless OS=Homo
sapiens OX=9606 GN=HR PE=1 SV=5
Length=1189
Score = 34.4 bits (77), Expect = 6.0, Method: Composition-based stats.
Identities = 22/129 (17%), Positives = 36/129 (28%), Gaps = 13/129 (10%)
Query 581 PPESSGCKTLTSS--QACVVCEEGFSLHQKSCVQH-CPPGFAPQVLDTHYSTENDVETIR 637
PP + C + Q + C G +E +
Sbjct 308 PPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEPSEEVNKASG 367
Query 638 ASVCAPCH----ASCATCQGPALTDC-LSCP-----SHASLDPVEQTCSRQSQSSRESPP 687
C P H + +C CP A L +++ S + Q + SP
Sbjct 368 PRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQGAMGSPA 427
Query 688 QQQPPRLPP 696
++PP P
Sbjct 428 PKRPPDPFP 436
>sp|Q8K3K1|USH2A_RAT Usherin OS=Rattus norvegicus OX=10116 GN=Ush2a
PE=1 SV=2
Length=5125
Score = 34.4 bits (77), Expect = 6.2, Method: Composition-based stats.
Identities = 23/157 (15%), Positives = 39/157 (25%), Gaps = 20/157 (13%)
Query 587 CKTLTSSQACVVCE------EGFSLHQKSCVQHCPPGFAPQVLDTHYSTENDVETIRASV 640
+ +++ C+ C + + + +CP +
Sbjct 935 YSSPSNATGCLPCLCHTVATKNCICNSVTGHCYCPDPSTTGLSWHQCQDRYFRFDPLTGR 994
Query 641 CAPCH-----ASCATCQGPALTDCLSCPSHASLDPVEQTCSRQSQSSRE------SPPQQ 689
C PCH AS TC C C + + TC + S
Sbjct 995 CRPCHCHVAGASNGTCDAVTG-QCF-CKEFVTGSKCD-TCVPGASHLDVNNLLACSKTPS 1051
Query 690 QPPRLPPEVEAGQRLRAGLLPSHLPEVVAGLSCAFIV 726
Q P V++ + P P F
Sbjct 1052 QQPPPRGRVQSSSAINLSWSPPDFPNAHWLTYTLFRD 1088
>sp|B2RUR4|KPRP_MOUSE Keratinocyte proline-rich protein OS=Mus
musculus OX=10090 GN=Kprp PE=2 SV=1
Length=657
Score = 33.6 bits (75), Expect = 9.8, Method: Composition-based stats.
Identities = 28/155 (18%), Positives = 43/155 (28%), Gaps = 33/155 (21%)
Query 571 YGTAPEGLPVPPESSGCKTLTSSQACVVCEEGFSLHQKSCVQHCPPGFAPQ--VLDTHYS 628
YG L S C + S A + + Q + Q T
Sbjct 249 YGNCTSQLQSRASYSNCSSQRRSGA-----TFSTCAPRCQSQGTYGSYTSQRRSQSTSRC 303
Query 629 TENDVETIRASVCAP------CHASC--ATCQGPALTDCLS-----------CPSHASLD 669
C+P C++SC + C + C CP
Sbjct 304 LPPRRLQPSYRSCSPPRHSEPCYSSCLPSRCSSGSYNYCTPPRRSEPIYGSHCPPRGRPS 363
Query 670 PVEQTCSRQSQ-------SSRESPPQQQPPRLPPE 697
Q C + + R+ PPQ+ P ++PP
Sbjct 364 GCSQRCGPKCRVEISSPCCPRQVPPQRCPVQIPPF 398
Lambda K H a alpha
0.318 0.123 0.333 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0375 0.140 1.90 42.6 43.6
Effective search space used: 89977505152
Database: uniprot_sprot.fasta
Posted date: Apr 3, 2024 12:05 PM
Number of letters in database: 206,678,396
Number of sequences in database: 571,282
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40