Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -1 -2 -3 -1 0 -2 -3 -2 1 2 -1 6 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.33 0.00 2 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.46 0.00 3 V 0 -2 -3 -3 -1 -1 -2 -3 -3 2 1 -2 4 -1 -3 -2 0 -2 -1 3 0 0 0 0 0 0 0 0 0 0 0 0 38 0 0 0 0 0 0 62 0.28 0.00 4 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -1 -3 -1 0 -1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.53 0.00 5 T 0 -2 -1 -2 6 -1 -1 -1 -2 -1 -2 -1 -1 -2 -2 2 3 -3 -2 -1 0 0 0 0 38 0 0 0 0 0 0 0 0 0 0 31 31 0 0 0 0.45 0.00 6 L -1 -2 -2 -3 -1 -2 -2 -3 -2 1 3 -2 1 0 -2 0 2 -2 -1 1 0 0 0 0 0 0 0 0 0 0 62 0 0 0 0 0 38 0 0 0 0.26 0.00 7 H -2 3 0 -1 -3 1 0 -2 7 -3 -3 1 -2 -2 -2 -1 -2 -3 1 -3 0 38 0 0 0 0 0 0 62 0 0 0 0 0 0 0 0 0 0 0 0.62 0.00 8 G 0 -1 -1 0 -2 0 3 3 -1 0 -1 -1 -1 -2 -2 -1 -1 -3 -2 1 0 0 0 0 0 0 38 31 0 0 0 0 0 0 0 0 0 0 0 31 0.23 0.00 9 P 0 -1 -1 -1 -1 -1 -1 -2 -2 -1 -2 -1 -1 -3 5 1 4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31 0 69 0 0 0 0.63 0.00 10 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.41 0.00 11 M -1 -1 -2 -3 -2 0 -2 -3 -2 1 2 -1 6 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.38 0.01 12 V 0 -3 -3 -3 -1 -2 -3 -3 -3 3 1 -2 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.36 0.00 13 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -1 -3 -1 0 -1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.53 0.01 14 Y 0 -1 -1 -1 -2 -1 -1 -1 1 -2 -2 -1 -1 1 -2 2 0 1 5 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49 0 0 51 0 0.38 0.00 15 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.46 0.00 16 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.46 0.00 17 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.46 0.00 18 S -1 -2 -2 -2 -1 -2 -2 -3 -2 1 3 -2 2 0 -2 1 0 -2 -1 0 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 25 0 0 0 0 0.25 0.00 19 I -1 -2 -3 -3 -1 -1 -3 -3 -2 3 2 -2 4 0 -3 -2 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 51 0 0 49 0 0 0 0 0 0 0 0.30 0.00 20 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.46 0.00 21 G 0 -2 0 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -3 -3 -3 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.05 0.00 22 L -2 -2 -3 -4 -2 -3 -3 -4 -2 1 4 -3 2 3 -3 -3 -1 -1 1 0 0 0 0 0 0 0 0 0 0 0 75 0 0 25 0 0 0 0 0 0 0.40 0.00 23 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.41 0.00 24 F -2 -3 -3 -4 -2 -3 -3 -4 -2 3 1 -3 1 5 -3 -3 -1 0 2 1 0 0 0 0 0 0 0 0 0 49 0 0 0 51 0 0 0 0 0 0 0.39 0.00 25 L -2 -2 -4 -4 -1 -2 -3 -4 -3 3 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 25 75 0 0 0 0 0 0 0 0 0 0.40 0.00 26 S 0 4 0 -1 -2 1 0 -1 -1 -3 -2 1 -2 -3 -1 3 0 -3 -2 -2 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0.41 0.00 27 E 0 0 0 1 -3 2 5 -2 0 -3 -3 1 -2 -3 -1 2 0 -3 -2 -2 0 0 0 0 0 0 75 0 0 0 0 0 0 0 0 25 0 0 0 0 0.55 0.00 28 A 2 -2 -1 -2 -1 -1 -2 2 -2 0 -1 -1 -1 -2 -2 0 2 -3 -2 1 25 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 26 0 0 25 0.20 0.00 29 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.41 0.00 30 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.41 0.00 31 R -1 5 0 -1 -3 3 1 -2 0 -3 -2 2 -1 -3 -2 -1 -1 -3 -2 -3 0 74 0 0 0 26 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.63 0.00 32 K -1 5 0 -1 -3 1 0 -2 -1 -3 -2 4 -1 -3 -2 -1 -1 -3 -2 -3 0 50 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0.56 0.00 33 I -1 -1 4 0 -2 -1 -1 -2 -1 2 0 -1 0 -2 -2 0 0 -3 -2 2 0 0 49 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 26 0.22 0.00 34 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.05 0.01 35 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -3 -1 0 -1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.56 0.01 36 V 2 -2 -2 -1 -1 0 1 -1 -2 1 -1 -1 0 -2 -1 0 0 -3 -2 2 44 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 0 0 37 0.17 0.01 37 G 0 -3 -1 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -3 -3 -3 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.07 0.01 38 H -1 -1 -1 -2 -2 2 -1 -3 3 1 1 -1 0 -1 -2 -1 -1 -2 0 2 0 0 0 0 0 20 0 0 19 0 18 0 0 0 0 0 0 0 0 44 0.15 0.01 39 T 0 -2 -1 -1 -1 -1 -1 -2 -2 1 -1 -1 0 -2 3 1 3 -3 -2 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 18 18 39 0 0 0 0.31 0.01 40 F 2 -2 -3 -3 -1 -2 -2 -2 -2 2 0 -2 0 4 -2 -1 -1 -1 1 1 36 0 0 0 0 0 0 0 0 25 0 0 0 39 0 0 0 0 0 0 0.21 0.01 41 F -2 -3 -3 -3 -2 -2 -3 -3 -2 0 2 -2 1 4 4 -2 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 36 0 0 39 25 0 0 0 0 0 0.46 0.01 42 Q -1 1 0 0 -3 6 2 -2 0 -3 -2 1 -1 -3 -1 0 -1 -2 -2 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.71 0.02 43 K 0 2 0 -1 -3 1 1 -1 -1 -3 -3 4 -2 -3 -1 2 0 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 75 0 0 0 25 0 0 0 0 0.41 0.01 44 P 2 -2 -2 -2 -2 -1 -1 -1 -2 -2 -2 -1 -2 -3 7 0 -1 -3 -3 -2 36 0 0 0 0 0 0 0 0 0 0 0 0 0 64 0 0 0 0 0 1.17 0.01 45 E 0 -1 0 0 -2 1 3 3 -1 -2 -2 0 -2 -2 -1 0 -1 -2 -2 -2 2 1 1 1 0 1 40 38 1 1 2 1 1 1 1 2 1 0 1 2 0.35 0.00 46 S 0 -1 4 0 -2 0 -1 3 -1 -3 -3 -1 -2 -3 -2 2 0 -3 -2 -3 0 0 36 0 0 0 0 25 0 0 0 0 0 0 0 39 0 0 0 0 0.42 0.01 47 C -1 -4 -3 -4 9 -3 -4 -3 -3 -1 -1 -3 -2 -3 -3 -1 -1 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.31 0.02 48 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.08 0.02 49 P 0 -2 -1 -1 -3 -1 -1 -2 -2 -3 -3 -1 -2 -4 7 1 0 -4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 20 0 0 0 0 1.55 0.01 50 V -1 -2 -2 -3 -1 -2 -2 -3 -3 2 2 -2 1 -1 -2 -1 2 -2 -1 2 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 25 0 0 39 0.23 0.00 51 P -1 -1 -1 1 -4 1 4 -2 -1 -3 -3 0 -2 -4 5 0 -1 -3 -3 -3 0 0 0 0 0 0 61 0 0 0 0 0 0 0 39 0 0 0 0 0 0.88 0.01 52 G -1 -1 1 5 -4 0 2 2 -1 -3 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 61 0 0 20 19 0 0 0 0 0 0 0 0 0 0 0 0 0.63 0.01 53 G -1 0 4 0 -3 0 -1 3 -1 -3 -3 2 -2 -3 -2 0 -1 -3 -3 -3 0 0 36 0 0 0 0 39 0 0 0 25 0 0 0 0 0 0 0 0 0.45 0.01 54 S 0 -1 4 0 -2 0 0 -1 0 -3 -3 0 -2 -3 -1 3 2 -3 -2 -2 0 0 37 0 0 0 0 0 0 0 0 0 0 0 0 51 12 0 0 0 0.42 0.02 55 M -1 -3 -3 -3 -1 -2 -3 -3 -3 2 2 -2 2 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 11 0 11 0 0 0 0 0 0 78 0.35 0.02 56 K -1 4 1 -1 -3 1 0 -2 -1 -2 -2 3 1 -3 -2 -1 -1 -3 -2 -2 0 38 9 0 0 0 0 0 0 0 0 42 11 0 0 0 0 0 0 0 0.42 0.02 57 L -1 -3 -3 -4 -1 -2 -3 -4 -3 2 2 -3 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 0 0 69 0.35 0.02 58 D -2 -1 5 4 -3 0 0 -1 0 -3 -3 -1 -3 -3 -2 0 1 -4 -3 -3 0 0 48 41 0 0 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0.61 0.02 59 I -2 -3 -4 -4 -1 -3 -3 -4 -3 3 3 -3 2 0 -3 -3 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 39 61 0 0 0 0 0 0 0 0 0 0.41 0.02 60 G -1 2 2 -1 -3 0 0 2 2 -3 -3 2 -2 -3 -2 1 -1 -3 -2 -3 0 19 19 0 0 0 0 22 9 0 0 20 0 0 0 11 0 0 0 0 0.31 0.01 61 I -1 -3 0 -3 -1 -3 -3 -3 -3 4 1 -2 1 -1 -3 -2 -1 -3 -2 3 0 0 9 0 0 0 0 0 0 71 0 0 0 0 0 0 0 0 0 20 0.32 0.02 62 I -2 2 -3 -3 -2 -2 -2 -3 -2 2 1 -1 0 3 -3 -2 -1 -1 1 1 0 20 0 0 0 0 0 0 0 32 10 0 0 29 0 0 0 0 0 9 0.21 0.01 63 N -2 -1 6 1 -3 0 0 -1 0 -4 -4 0 -2 -3 -2 0 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.86 0.04 64 E 0 2 0 0 -3 2 3 -2 -1 -3 -2 1 -2 -3 -2 1 0 4 -1 -2 8 14 0 0 0 14 34 0 0 0 0 0 0 0 0 15 6 8 0 0 0.35 0.02 65 N 0 -1 4 0 -2 0 -1 1 0 -2 -1 -1 -2 -3 -2 3 0 -3 -2 -2 0 0 44 0 0 0 0 7 0 0 8 0 0 0 0 41 0 0 0 0 0.39 0.03 66 Q 0 -1 -1 -1 6 3 0 -2 -1 -2 -2 0 -1 -3 -2 1 2 -3 -2 -1 7 0 0 0 27 30 0 0 0 0 0 0 0 0 0 8 28 0 0 0 0.38 0.03 67 R -1 4 2 -1 -3 0 0 1 -1 -3 -3 1 -2 -3 1 1 -1 -3 -2 -3 0 42 13 0 0 0 0 14 0 0 0 7 0 0 8 15 0 0 0 0 0.37 0.02 68 V 2 -1 -2 -2 -1 -1 -1 -1 -2 1 -1 0 0 -2 1 1 0 -3 -2 2 34 0 0 0 0 0 0 0 0 14 0 8 0 0 6 14 0 0 0 23 0.16 0.02 69 S 1 2 0 -1 -2 0 0 -1 -1 -3 -3 2 -2 -3 2 3 0 -3 -2 -2 8 14 0 0 0 0 0 0 0 0 0 14 0 0 8 56 0 0 0 0 0.36 0.03 70 M -1 2 -1 -1 -2 0 1 -2 -1 0 1 1 1 -1 -2 0 -1 -3 -2 0 0 23 0 0 0 0 11 0 0 0 25 11 6 0 0 12 0 0 0 12 0.13 0.02 71 S 0 0 0 3 -3 0 2 -1 -1 -3 -3 0 -2 -3 4 2 0 -4 -3 -2 6 6 0 22 0 0 19 0 0 0 0 0 0 0 24 23 0 0 0 0 0.50 0.03 72 R 1 3 -1 -1 -2 0 -1 2 -1 -3 -3 0 -2 -3 -2 1 0 -3 -2 -2 19 36 0 0 0 0 0 22 0 0 0 0 0 0 0 17 5 0 0 0 0.33 0.03 73 N -2 -2 2 5 -4 -1 1 -2 -1 -3 -4 -1 -3 -4 4 -1 -1 -4 -3 -3 0 0 12 59 0 0 6 0 0 0 0 0 0 0 22 0 0 0 0 0 0.81 0.05 74 I -2 -2 -2 -3 -2 -2 -2 -3 0 1 1 -2 0 3 -3 -1 1 0 5 0 0 0 0 0 0 0 0 0 0 12 22 0 0 12 0 0 19 0 34 0 0.32 0.03 75 E -1 -1 3 0 -3 2 1 -2 5 -2 -1 0 -1 -1 -2 0 -1 -2 2 -2 0 0 22 0 0 12 12 0 25 0 12 0 0 0 0 6 0 0 11 0 0.28 0.03 76 S -1 1 4 0 -2 2 1 -1 0 -3 -3 1 -2 -3 -2 2 0 -3 -2 -3 0 6 35 0 0 9 10 0 0 0 0 12 0 0 0 28 0 0 0 0 0.38 0.03 77 R -2 7 -1 -2 -4 0 -1 -3 -1 -4 -3 2 -2 -4 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.14 0.12 78 S 2 -1 0 -1 -1 -1 -1 -1 -2 -3 -3 -1 -2 0 -1 4 1 -3 -2 -2 16 0 0 0 0 0 0 0 0 0 0 0 0 5 0 79 0 0 0 0 0.52 0.09 79 T -1 -2 -2 -2 -1 -2 -2 -3 -3 3 1 -2 0 -1 -2 0 3 -3 -2 2 0 0 0 0 0 0 0 0 0 31 17 0 0 0 0 8 34 0 0 10 0.25 0.05 80 S 1 -1 0 -1 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.75 0.12 81 P -2 -3 -3 -2 -4 -2 -2 -3 -3 -4 -4 -2 -3 -4 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.33 0.13 82 W -4 -4 -5 -5 -3 -3 -4 -4 -3 -4 -3 -4 -2 0 -5 -4 -3 12 1 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 3.09 0.19 83 N 1 2 2 1 -2 0 -1 2 -1 -3 -3 0 -2 -3 -2 1 2 -3 -2 -2 10 23 12 8 0 0 0 17 0 0 0 0 0 0 0 8 22 0 0 0 0.26 0.04 84 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -1 2 -3 0 2 -4 -3 -2 1 7 -1 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 75 0 0.90 0.11 85 T -1 3 1 0 -3 1 2 -2 4 -3 -3 0 -2 -3 -2 2 1 -3 -1 -2 0 25 8 0 0 5 16 0 16 0 0 0 0 0 0 21 9 0 0 0 0.34 0.04 86 V -1 2 -3 -3 -2 -1 -2 -4 -2 3 2 -1 1 -1 -3 -2 -1 -3 -2 2 0 25 0 0 0 0 0 0 0 43 16 0 0 0 0 0 0 0 0 15 0.28 0.05 87 T -1 -1 4 4 -3 -1 0 -1 -1 -3 -3 -1 -2 -3 -2 1 2 -4 -3 -3 0 0 42 31 0 0 0 0 0 0 0 0 0 0 0 10 17 0 0 0 0.57 0.07 88 W -2 3 -1 -1 -3 0 2 -3 4 -3 -2 0 -2 -1 -2 -1 1 4 2 -2 0 24 0 0 0 0 25 0 17 0 0 0 0 0 0 0 15 9 10 0 0.38 0.05 89 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.30 0.12 90 P -1 -2 -2 -1 -3 0 1 -3 -2 -2 0 -1 -1 -3 7 -1 -2 -4 -3 -2 0 0 0 0 0 5 15 0 0 0 16 0 0 0 65 0 0 0 0 0 1.20 0.08 91 N 0 -1 4 3 -3 0 2 -1 1 -3 -3 -1 -2 -3 -2 1 0 -4 -2 -3 10 0 33 23 0 0 12 0 5 0 0 0 0 0 0 17 0 0 0 0 0.43 0.05 92 R -2 7 -1 -2 -4 0 -1 -3 -1 -4 -3 2 -2 -4 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.14 0.12 93 Y -2 -3 -3 -4 -2 -2 -3 -4 0 2 0 -3 0 3 -3 -2 -2 1 6 1 0 0 0 0 0 0 0 0 0 17 8 0 0 8 0 0 0 0 59 8 0.65 0.08 94 P -1 -3 -3 -2 -3 -2 -2 -3 -3 -4 -4 -2 -3 -4 8 0 -2 -4 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95 5 0 0 0 0 2.16 0.13 95 S 1 1 0 -1 -2 3 0 -1 -1 -2 -2 0 -1 -3 -2 3 0 -3 -2 -1 11 10 0 0 0 31 0 0 0 0 0 0 0 0 0 42 0 0 0 5 0.35 0.06 96 E -1 -1 0 4 -3 0 2 -2 -1 -1 -2 1 -1 -1 -2 -1 -1 -2 1 1 0 0 0 33 0 0 17 0 0 0 0 15 0 0 0 0 0 0 10 25 0.26 0.05 97 V -2 -3 -4 -4 -2 -3 -3 -4 -3 3 4 -3 1 0 -3 -3 -1 -2 -2 2 0 0 0 0 0 0 0 0 0 34 58 0 0 0 0 0 0 0 0 9 0.48 0.06 98 V 1 -3 -3 -3 -2 -2 -2 -2 -1 -2 -2 -2 -2 0 4 -1 -1 7 3 0 23 0 0 0 0 0 0 0 0 0 0 0 0 0 27 0 0 25 16 9 0.77 0.07 99 Q -1 -1 -1 0 -4 2 5 -3 4 -2 -2 0 -2 0 -2 -1 -1 -3 -1 -1 0 0 0 0 0 9 61 0 16 0 0 0 0 7 0 0 0 0 0 8 0.52 0.07 100 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -2 -3 -1 1 -1 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.68 0.10 101 Q -1 4 -1 -1 -4 3 2 -2 0 -3 -3 2 -1 -2 -2 -1 -1 -2 2 -3 0 33 0 0 0 25 15 0 0 0 0 17 0 0 0 0 0 0 10 0 0.48 0.06 102 C -1 -4 -4 -4 10 -4 -5 -3 -4 -2 -2 -4 -2 -3 -4 -2 -2 -3 -3 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.96 0.16 103 R -1 3 -2 -3 -2 -1 -2 -3 -2 0 3 0 1 -1 -3 0 -1 -2 -2 0 0 33 0 0 0 0 0 0 0 0 58 0 0 0 0 9 0 0 0 0 0.32 0.06 104 N -1 -2 0 -3 8 -2 -2 -3 6 -2 -2 -3 -2 -2 -3 -1 -2 -3 1 -2 0 0 4 0 58 0 0 0 33 0 0 0 0 0 0 0 0 0 5 0 1.05 0.11 105 L -1 3 -1 -2 -2 1 -1 -2 -2 -1 2 0 0 -2 3 1 -1 -3 -2 -1 0 25 0 0 0 8 0 0 0 0 34 0 0 0 16 17 0 0 0 0 0.26 0.05 106 G -1 0 -1 -2 -3 -1 -2 5 4 -4 -4 -1 -3 -3 -3 -1 -2 -3 -2 -4 0 8 0 0 0 0 0 76 16 0 0 0 0 0 0 0 0 0 0 0 0.88 0.08 107 C -1 -4 -4 -4 10 -4 -5 -3 -4 -2 -2 -4 -2 -3 -4 -2 -2 -3 -3 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.96 0.16 108 I -1 -3 -4 -4 -1 -3 -3 -4 -4 4 2 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 40 10 0 0 0 0 0 0 0 0 50 0.47 0.06 109 N -1 -1 6 2 -3 -1 -1 -1 0 -3 -4 -1 -2 -3 -2 2 1 -4 -3 -3 0 0 67 7 0 0 0 0 0 0 0 0 0 0 0 16 10 0 0 0 0.68 0.08 110 A 3 -2 -2 -2 -1 -2 -2 1 -2 -1 0 -1 -1 -2 3 0 -1 -3 -2 -1 57 0 0 0 0 0 0 10 0 0 16 0 0 0 17 0 0 0 0 0 0.38 0.06 111 Q -1 1 0 1 -3 4 2 -2 -1 -2 -1 1 -1 -3 -2 0 1 -3 -2 -2 0 7 0 8 0 33 17 0 0 0 10 8 0 0 0 0 17 0 0 0 0.31 0.05 112 G 0 -2 -1 -2 -2 -2 -2 5 -2 -2 -2 -2 2 -3 -2 1 -1 -3 -3 -2 0 0 0 0 0 0 0 67 0 0 0 0 17 0 0 16 0 0 0 0 0.69 0.08 113 K -1 2 1 -1 -4 3 2 -2 4 -3 -3 3 -2 -3 -2 -1 -1 -3 -1 -3 0 15 8 0 0 25 10 0 16 0 0 26 0 0 0 0 0 0 0 0 0.45 0.05 114 E -1 -1 -1 0 -3 1 5 -3 -1 -1 0 0 3 -2 -2 -1 -1 -3 -2 0 0 0 0 0 0 0 63 0 0 0 8 0 16 0 0 0 0 0 0 12 0.44 0.08 115 D -2 -2 1 6 -4 -1 1 -2 -2 -3 -4 -1 -3 -4 -2 0 1 -5 -3 -3 0 0 0 85 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 1.00 0.10 116 I 1 2 -1 -2 -2 -1 -1 -1 4 0 -1 -1 -1 -1 3 0 -1 -2 1 0 15 17 0 0 0 0 0 4 17 9 0 0 0 0 16 5 0 0 8 10 0.21 0.03 117 S 1 2 0 -2 -2 0 -1 -2 5 -2 -1 0 -1 0 -2 2 0 -3 0 -2 15 19 0 0 0 0 0 0 25 0 8 0 0 4 0 25 5 0 0 0 0.24 0.05 118 M -1 -2 -3 -3 -2 -2 -3 1 -2 0 2 -2 6 2 -3 -2 -2 -2 -1 0 0 0 0 0 0 0 0 16 0 0 15 0 59 10 0 0 0 0 0 0 0.43 0.09 119 N -2 1 6 0 -3 -1 -1 -1 0 -2 -3 -1 -2 -3 -3 0 -1 -4 -2 0 0 10 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0.62 0.09 120 S 1 -1 0 -1 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.75 0.12 121 V 1 -3 -3 -3 -1 -2 0 -3 -3 2 0 -2 0 -2 -3 -2 -1 -3 -2 4 10 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 81 0.40 0.08 122 P 0 0 -2 -2 -2 -1 -1 -2 -2 -2 0 -1 -1 -2 6 -1 0 -3 -2 -2 5 7 0 0 0 0 0 1 0 0 17 0 0 0 61 1 4 0 0 1 1.04 0.07 123 I -1 -3 -3 -3 -1 -2 -3 -3 -3 4 2 -3 1 0 -3 -2 -1 -2 -1 3 1 0 0 0 0 0 0 1 0 43 24 0 0 0 0 1 0 0 0 28 0.35 0.04 124 Q -2 -1 -1 -2 -3 5 0 -3 0 -2 0 0 -1 3 -3 -1 -2 0 4 -2 0 0 0 0 0 50 0 0 0 0 7 0 0 17 0 0 0 0 27 0 0.50 0.08 125 Q -1 0 0 -1 -3 5 0 -2 4 -2 0 0 2 -2 -2 1 -1 -3 -1 -2 0 0 0 0 0 49 0 0 16 0 8 0 10 0 0 17 0 0 0 0 0.40 0.08 126 E -1 -1 2 0 -3 3 4 -2 -1 -3 -1 0 -1 -3 2 0 -1 -3 -2 -2 0 0 16 0 0 17 42 0 0 0 8 0 0 0 10 7 0 0 0 0 0.43 0.05 127 T -1 -1 -2 -2 -2 2 -1 -3 -2 3 1 -1 0 -1 -2 -1 2 -3 -2 2 0 0 0 0 0 24 0 0 0 34 7 0 0 0 0 0 19 0 0 17 0.22 0.05 128 L -1 -2 -2 -3 -2 -2 -2 -3 -3 1 3 -2 1 -1 3 0 1 -3 -2 1 0 0 0 0 0 0 0 0 0 0 49 0 0 0 17 8 16 0 0 10 0.31 0.05 129 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 1 -3 0 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 92 0.58 0.09 130 V -2 2 -3 -4 -2 -2 -3 -4 -2 1 3 -1 1 3 -3 -2 -2 -2 0 1 0 17 0 0 0 0 0 0 0 0 58 0 0 16 0 0 0 0 0 9 0.32 0.05 131 R -2 5 -1 -2 -3 0 -1 -3 0 -2 -2 2 -2 -1 -3 -1 -2 -2 3 -1 0 68 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 16 8 0.62 0.08 132 R -2 6 -1 -2 -4 0 -1 -3 -1 -3 -1 2 -1 -3 -3 -1 -2 -3 -2 -3 0 88 0 0 0 0 0 0 0 0 8 5 0 0 0 0 0 0 0 0 0.89 0.10 133 K -1 4 -1 -1 -3 1 3 -1 -1 -2 0 2 -1 -3 -2 -1 1 -3 -2 -2 0 36 0 0 0 0 29 5 0 0 12 9 0 0 0 0 10 0 0 0 0.32 0.05 134 H -1 0 -1 -1 3 0 1 -2 3 -3 -3 -1 -2 -3 5 0 -1 -3 -2 -2 1 8 0 0 12 0 17 1 14 0 1 0 0 0 41 4 0 0 0 0 0.71 0.06 135 Q 0 1 -1 -1 -3 4 2 0 -1 -3 -2 1 -1 -3 3 0 -1 -3 -2 -2 11 5 0 0 0 34 17 6 0 0 1 9 0 0 15 0 0 0 0 0 0.40 0.04 136 G -1 -2 -1 -2 -3 -1 -2 4 3 -4 -4 -1 -3 -3 5 0 -2 -3 -2 -3 0 0 0 0 0 0 0 43 12 0 0 4 0 0 36 4 0 0 0 0 0.84 0.07 137 C -1 -3 -2 -3 9 -3 -3 0 -3 -2 -2 -3 -2 -3 1 -1 1 -3 -3 -1 0 0 0 0 67 0 0 10 0 0 0 0 0 0 6 0 16 0 0 0 1.04 0.10 138 S -1 2 -1 -1 -3 0 -1 -2 4 -3 -3 0 -2 -3 5 2 0 -3 -1 -3 0 21 0 0 0 0 0 0 16 0 0 0 0 0 31 32 0 0 0 0 0.62 0.07 139 V -1 2 3 -1 -3 1 -1 -2 1 -1 -1 1 -1 3 -2 0 -1 -2 0 -1 0 14 21 0 0 10 0 0 4 0 0 8 0 23 0 10 0 0 0 9 0.17 0.04 140 S 1 2 -1 -1 -2 -1 -1 1 -2 -1 -2 0 -1 -3 1 2 1 -3 -2 0 15 18 0 0 0 0 0 8 0 0 0 0 0 0 6 34 8 0 0 10 0.22 0.04 141 F -1 -3 -3 -4 -3 -3 -3 -1 -1 -1 -1 -3 -1 6 -4 -2 -2 1 5 0 5 0 0 0 0 0 0 6 0 0 0 0 0 57 0 0 0 0 27 5 0.67 0.08 142 Q -1 3 -1 -2 4 1 -1 -3 3 -2 -2 0 -1 -3 1 -1 1 -3 -1 0 0 34 0 0 16 9 0 0 15 0 0 0 0 0 6 0 10 0 0 10 0.31 0.05 143 L -1 -2 -2 -2 2 -1 0 -3 -2 1 3 -2 2 -1 -3 -1 1 -2 -2 1 0 0 0 0 6 0 10 0 0 0 50 0 10 0 0 0 15 0 0 8 0.24 0.04 144 E 0 1 -1 1 -4 1 5 -2 -1 -4 -3 0 -2 -4 -2 -1 -1 -3 -3 -3 10 6 0 0 0 0 83 0 0 0 0 0 0 0 0 0 0 0 0 0 0.78 0.09 145 K -1 3 -1 -2 -3 0 0 -2 2 -2 -2 3 -1 2 -2 -1 0 -1 2 -2 0 16 0 0 0 0 0 0 6 0 0 42 0 15 0 0 10 0 10 0 0.31 0.05 146 V -1 2 -2 -3 -2 -1 -2 -3 -2 2 1 -1 4 -1 -2 -2 -1 -2 -1 2 1 23 0 1 0 0 1 1 0 19 5 1 25 0 1 1 1 0 0 20 0.20 0.04 147 L -1 0 -2 -3 -2 -1 -2 -3 1 1 3 -1 2 0 -2 -1 1 -2 -1 1 1 8 0 1 0 0 1 1 7 1 54 1 5 0 1 1 11 0 0 7 0.20 0.04 148 V -1 -3 -4 -4 -1 -3 -3 -4 -4 3 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 25 5 0 0 0 0 0 0 0 0 71 0.51 0.07 149 T 2 -1 -1 -1 -2 -1 -1 1 -2 -2 -2 0 -2 -3 4 2 2 -3 -2 -1 21 0 0 0 0 0 0 8 0 0 0 8 0 0 25 20 18 0 0 0 0.45 0.04 150 V -1 -3 -4 -4 -1 -3 -3 -4 -4 2 2 -3 1 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 84 0.52 0.08 151 G 1 -3 -1 -2 -3 -2 -2 6 -3 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -3 16 0 0 0 0 0 0 84 0 0 0 0 0 0 0 0 0 0 0 0 1.03 0.08 152 C -1 -4 -4 -4 10 -4 -5 -3 -4 -2 -2 -4 -2 -3 -4 -2 -2 -3 -3 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.96 0.16 153 T -1 -2 -1 -2 -1 -1 -2 -2 -2 0 -1 -1 -1 -2 -2 1 5 -3 -2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84 0 0 16 0.62 0.10 154 C -1 -4 -4 -4 10 -4 -5 -3 -4 -2 -2 -4 -2 -3 -4 -2 -2 -3 -3 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.96 0.16 155 V -1 -3 -4 -4 -1 -3 -3 -4 -4 3 1 -3 0 -1 -3 -2 -1 -3 -2 5 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 0 0 86 0.56 0.08 156 T 0 2 -1 -2 -2 0 -1 -2 -1 -1 1 1 0 -2 -2 1 3 -3 -2 -1 6 22 0 0 0 0 0 0 0 0 19 12 0 0 0 6 34 0 0 0 0.20 0.03 157 P -1 -2 -2 -2 -3 -2 -1 -2 -2 -3 -3 -1 -3 -4 8 1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88 12 0 0 0 0 1.87 0.08 158 V -1 2 -2 -3 -2 -1 -2 -4 -2 4 1 -1 1 -1 -3 -2 -1 -3 -2 2 0 27 0 0 0 0 0 0 0 58 8 0 0 0 0 0 0 0 0 8 0.27 0.03 159 I -1 -3 -3 -4 -1 -3 -3 -4 -4 3 1 -3 1 -1 -3 -2 0 -3 -2 4 0 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 84 0.46 0.04 160 H -2 4 0 -2 -3 1 0 -2 7 -3 -3 1 -2 -2 -2 -1 -2 -3 1 -3 0 39 0 0 0 0 0 0 61 0 0 0 0 0 0 0 0 0 0 0 0.71 0.03 161 H -2 0 2 -1 -3 3 0 -2 7 -3 -3 0 -2 -2 -2 -1 -1 -3 1 -3 0 0 11 0 0 20 0 0 69 0 0 0 0 0 0 0 0 0 0 0 0.73 0.03 162 V 2 -2 -3 -3 -1 -2 -2 -2 -3 2 1 -2 0 -1 -2 -1 0 -3 -2 3 34 0 0 0 0 0 0 0 0 11 10 0 0 0 0 0 0 0 0 45 0.21 0.01 163 Q -1 0 1 4 -3 3 1 -2 5 -3 -3 0 -2 -3 -2 0 -1 -3 0 -3 0 0 0 39 0 31 0 0 31 0 0 0 0 0 0 0 0 0 0 0 0.50 0.00 K Lambda Standard Ungapped 0.1330 0.3195 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1330 0.3195 PSI Gapped 0.0410 0.2670