Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -1 -2 -3 -1 0 -2 -3 -2 1 2 -1 6 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.36 0.01 2 A 4 -2 -2 -2 0 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.44 0.02 3 L -1 -2 -3 -4 -2 -2 -3 -4 -3 1 4 -2 4 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 65 0 35 0 0 0 0 0 0 0 0.43 0.03 4 A 3 -1 -1 2 -1 -1 0 -1 3 -1 0 -1 -1 -2 -2 0 -1 -3 -1 -1 50 0 0 17 0 0 0 0 17 0 16 0 0 0 0 0 0 0 0 0 0.18 0.02 5 P 0 -1 -1 0 -2 0 1 -2 -1 -3 -3 0 -2 -3 6 2 0 -3 -2 -2 0 0 0 0 0 0 16 0 0 0 0 0 0 0 48 36 0 0 0 0 0.88 0.03 6 E -1 1 -1 0 -3 1 3 1 -1 -2 -2 0 -2 -3 2 -1 -1 -3 -2 0 0 14 0 0 0 0 43 16 0 0 0 0 0 0 14 0 0 0 0 13 0.32 0.02 7 R -1 5 -1 -2 -3 0 -1 1 -1 -3 -2 1 -2 -3 -2 0 1 -3 -2 -2 0 70 0 0 0 0 0 14 0 0 0 0 0 0 0 0 16 0 0 0 0.52 0.04 8 A 2 -1 0 2 -1 -1 0 2 -1 -2 -2 -1 -1 -2 3 0 0 -2 -2 -1 30 1 1 16 1 1 2 15 1 1 3 2 1 1 18 2 2 0 1 2 0.27 0.01 9 A 2 2 -1 -1 -1 0 0 -1 -1 0 -1 2 -1 -2 -1 0 0 -2 -1 0 28 17 1 2 1 1 2 2 1 1 3 18 1 1 1 2 2 0 1 15 0.11 0.01 10 P -1 -1 -1 -1 4 2 0 -2 -1 -2 -2 0 -1 -2 5 -1 -1 -2 -2 -2 2 1 1 1 15 24 2 2 1 1 2 1 1 1 40 2 1 0 1 2 0.65 0.02 11 R -1 5 -1 -2 -3 1 0 -2 -1 -3 -2 2 -1 -3 -2 -1 1 -3 -2 -2 1 72 0 0 0 0 1 1 0 0 1 10 0 0 0 1 11 0 0 1 0.61 0.05 12 V -1 1 -3 -3 -1 -2 -2 -3 -3 3 1 -1 3 -1 -3 -2 -1 -3 -1 3 0 11 0 0 0 0 0 0 0 23 9 0 17 0 0 0 0 0 0 40 0.27 0.04 13 L -2 4 -2 -2 -3 0 -1 -3 -1 -1 2 2 0 -1 -3 -2 -1 -3 -2 -1 0 48 0 0 0 0 0 0 0 0 41 11 0 0 0 0 0 0 0 0 0.37 0.05 14 F -1 -2 -2 -2 -1 -1 -2 -2 -2 1 2 -2 3 3 -2 -2 -1 0 1 0 2 1 1 1 0 1 1 2 1 1 35 1 18 28 1 2 1 0 1 1 0.23 0.02 15 G -1 3 0 -1 -2 0 0 3 -1 -2 -2 2 -1 -2 -1 0 -1 -2 -2 -2 2 29 1 1 0 1 1 29 1 1 2 23 1 1 1 2 1 0 1 1 0.31 0.02 16 E -1 -1 1 1 -3 2 1 -2 -1 -3 -3 -1 -2 -4 6 -1 -1 -4 -3 -3 0 0 8 9 0 15 7 0 0 0 0 0 0 0 61 0 0 0 0 0 1.18 0.07 17 W -3 -4 -5 -5 -3 -3 -4 -3 -3 -3 -3 -4 -2 0 -5 -4 -3 11 1 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 3.05 0.18 18 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 6 87 0 0 0 0 0 0 0 0 6 0.58 0.07 19 L -1 -2 -3 -2 -2 -1 1 -3 -3 3 2 -2 1 -1 -3 -2 -1 -3 -2 3 0 0 0 0 0 0 16 0 0 23 22 0 0 0 0 0 0 0 0 39 0.26 0.04 20 G 1 -1 1 1 -2 0 2 2 -1 -2 -2 0 1 -3 -2 1 0 -3 -2 -2 17 0 7 8 0 0 23 15 0 0 0 0 11 0 0 19 0 0 0 0 0.23 0.03 21 E 0 0 -1 -1 -3 6 3 -2 0 -3 -3 1 -1 -4 -2 -1 -1 -3 -2 -3 7 0 0 0 0 78 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0.79 0.10 22 I -1 -3 -3 -4 -1 -3 -3 -4 -3 3 2 -3 1 -1 -3 -2 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 36 19 0 0 0 0 0 0 0 0 45 0.43 0.05 23 S -1 -1 4 4 -3 0 2 -1 -1 -3 -4 -1 -3 -3 -2 2 0 -4 -3 -3 0 0 31 34 0 0 13 0 0 0 0 0 0 0 0 22 0 0 0 0 0.56 0.06 24 S 0 0 0 -1 -2 1 -1 -1 -1 -2 -1 -1 -1 -3 -1 4 1 -3 -2 -2 0 5 0 0 0 5 0 0 0 0 9 0 0 0 0 81 0 0 0 0 0.46 0.09 25 G 0 -2 2 -1 3 -2 -2 5 -2 -4 -4 -2 -3 -3 -3 0 -1 -3 -3 -3 0 0 16 0 10 0 0 69 0 0 0 0 0 0 0 5 0 0 0 0 0.78 0.07 26 C -1 0 -1 -1 2 4 1 -2 2 -2 0 1 1 -2 -2 -1 0 -2 -1 -2 0 0 0 0 7 49 5 0 6 0 14 8 5 0 0 0 6 0 0 0 0.33 0.06 27 Y -2 -3 -3 -4 -2 -2 -3 -4 0 1 1 -3 0 3 -3 -2 -2 1 6 0 0 0 0 0 0 0 0 0 0 16 19 0 0 13 0 0 0 0 52 0 0.60 0.07 28 E -1 0 -2 -1 -4 0 3 -3 -2 -3 -3 0 -3 -4 6 -1 -1 -4 -3 -3 0 7 0 0 0 0 34 0 0 0 0 0 0 0 59 0 0 0 0 0 1.23 0.09 29 G 0 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.31 0.10 30 L -1 -3 -4 -4 -1 -3 -3 -4 -3 2 4 -3 1 0 -3 -3 -1 -2 -1 3 0 0 0 0 0 0 0 0 0 0 69 0 0 0 0 0 0 0 0 31 0.48 0.06 31 Q 1 -1 -2 -2 5 2 -1 -2 -2 2 -1 0 0 -2 -2 -1 -1 -3 -2 1 19 0 0 0 20 25 0 0 0 23 0 6 0 0 0 0 0 0 0 8 0.22 0.05 32 W -3 -4 -5 -5 -3 -3 -4 -3 -3 -3 -3 -4 -2 0 -5 -4 -3 11 1 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 3.05 0.18 33 L -1 -2 -2 1 -2 -1 1 -3 -2 2 3 -2 1 -1 -3 -2 -1 -3 -2 2 0 0 0 13 0 0 13 0 0 18 42 0 0 0 0 0 0 0 0 15 0.21 0.04 34 D -2 -1 5 4 -3 -1 0 0 2 -4 -4 -1 -3 -3 -2 0 -1 -4 -2 -3 0 0 52 36 0 0 0 5 7 0 0 0 0 0 0 0 0 0 0 0 0.72 0.08 35 E 0 1 -1 1 -3 1 3 1 -1 -3 -3 2 -2 -3 1 0 0 -3 -2 -2 6 7 0 5 0 0 37 10 0 0 0 21 0 0 7 0 6 0 0 0 0.35 0.04 36 A 2 -1 0 3 -2 0 3 0 -1 -3 -3 0 -2 -3 -1 1 -1 -3 -2 -2 27 0 0 19 0 0 34 5 0 0 0 0 0 0 0 14 0 0 0 0 0.38 0.05 37 R -1 4 0 -1 -3 1 1 -2 1 -3 -3 4 -2 -3 -2 0 -1 -3 -2 -3 0 36 0 0 0 0 5 0 5 0 0 47 0 0 0 7 0 0 0 0 0.54 0.06 38 T -1 1 -1 -1 -2 0 -1 -2 -2 -1 -1 2 2 -2 -2 1 4 -3 -2 -1 0 7 0 0 0 0 0 0 0 0 0 23 11 0 0 8 51 0 0 0 0.33 0.06 39 C -1 2 -2 -3 2 -1 -2 -3 -2 2 1 -1 3 -1 -3 -2 -1 -3 -2 1 0 26 0 0 7 0 0 0 0 27 10 0 17 0 0 0 0 0 0 12 0.22 0.04 40 F -3 -3 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 -1 7 -4 -3 -3 0 2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.19 0.12 41 R -2 5 -1 -2 1 3 0 -3 0 -3 -3 1 -2 -3 -2 -1 -1 -2 0 -3 0 66 0 0 5 24 0 0 0 0 0 0 0 0 0 0 0 0 5 0 0.68 0.08 42 V -2 -3 -4 -4 -2 -3 -4 -4 -4 5 1 -3 1 -1 -3 -3 -1 -3 -2 3 0 0 0 0 0 0 0 0 0 85 0 0 0 0 0 0 0 0 0 15 0.61 0.09 43 P -1 -3 -3 -2 -4 -2 -2 -3 -3 -3 -4 -2 -3 -4 8 -1 -2 -4 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.31 0.13 44 W -3 -4 -5 -5 -3 -3 -4 -3 -3 -3 -3 -4 -2 0 -5 -4 -3 11 1 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 3.05 0.18 45 K -1 3 -1 -1 -3 1 0 -2 -1 -3 -2 5 0 -3 -2 -1 -1 -3 -2 -3 0 10 0 0 0 0 0 0 0 0 0 84 6 0 0 0 0 0 0 0 0.67 0.09 46 H -2 -1 0 -2 -4 0 -1 -3 9 -4 -4 -1 -2 -2 -3 -2 -2 -3 1 -4 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 1.52 0.15 47 F 3 -2 0 -2 -1 -1 -2 2 -2 -2 -2 -1 -1 2 -2 0 -1 -2 -1 -1 59 0 7 0 0 0 0 19 0 0 0 0 0 15 0 0 0 0 0 0 0.33 0.06 48 A 2 -2 -1 -2 -1 -2 -2 3 -2 -1 0 -1 -1 -2 -2 0 1 -3 -2 -1 30 0 0 0 0 0 0 34 0 0 19 0 0 0 0 0 17 0 0 0 0.29 0.04 49 R -2 5 -1 -2 -4 1 0 -2 -1 -3 -3 4 -2 -3 -2 -1 -1 -3 -2 -3 0 64 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 0 0 0 0.79 0.08 50 K -2 2 0 -1 -3 4 1 -2 6 -3 -3 2 -1 -3 -2 -1 -1 -3 0 -3 0 8 0 0 0 44 0 0 34 0 0 14 0 0 0 0 0 0 0 0 0.64 0.08 51 D -2 -2 1 6 -4 -1 1 2 -2 -4 -4 -1 -3 -4 -2 0 -1 -4 -3 -4 0 0 0 77 0 0 0 16 0 0 0 0 0 0 0 7 0 0 0 0 0.87 0.08 52 L 1 -2 -2 -3 -2 0 -2 -2 -1 0 1 -2 1 2 2 -1 -1 3 2 0 19 0 0 0 0 7 0 0 0 5 15 0 5 13 10 0 0 6 13 7 0.18 0.03 53 S -1 2 3 2 -2 3 1 -1 0 -3 -3 0 -2 -3 -2 1 1 -3 -2 -2 0 13 19 14 0 26 0 0 0 0 0 0 0 0 0 17 7 0 0 0 0.34 0.04 54 E -1 0 0 1 -3 3 4 -2 -1 -3 -3 1 0 -3 -2 0 -1 -3 -2 -3 0 0 0 5 0 19 59 0 0 0 0 5 5 0 0 7 0 0 0 0 0.58 0.07 55 A 1 0 -1 0 -2 2 3 1 -1 -2 -2 1 -1 -3 -1 1 -1 -3 -2 -1 12 0 0 0 0 13 38 11 0 0 0 11 0 0 0 7 0 0 0 5 0.30 0.04 56 D -2 -2 1 6 -4 -1 2 -2 -2 -4 -4 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 93 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 1.17 0.10 57 A 3 -2 2 -2 -1 -1 -1 -1 -1 -1 -1 -1 -1 2 -2 0 -1 -2 0 0 57 0 17 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 7 0.26 0.06 58 R 1 0 -1 -1 3 1 0 2 -2 -2 -2 0 -2 -3 1 1 1 -3 -2 -1 21 7 0 0 11 8 7 19 0 0 0 0 0 0 6 5 17 0 0 0 0.22 0.03 59 I -2 -3 -4 -4 -2 -3 -4 -4 -3 4 2 -3 1 1 -3 -3 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 69 25 0 0 6 0 0 0 0 0 0 0.49 0.07 60 F -3 -3 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 -1 7 -4 -3 -3 0 2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 1.19 0.12 61 K -1 3 -1 -1 -4 3 1 -2 -1 -3 -3 5 -2 -4 -2 -1 -1 -3 -2 -3 0 16 0 0 0 19 0 0 0 0 0 65 0 0 0 0 0 0 0 0 0.63 0.08 62 A 4 -2 0 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 2 0 -3 -2 -1 84 0 6 0 0 0 0 0 0 0 0 0 0 0 0 11 0 0 0 0 0.51 0.08 63 W -3 -4 -5 -5 -3 -3 -4 -3 -3 -3 -3 -4 -2 0 -5 -4 -3 11 1 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 3.05 0.18 64 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 -1 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.66 0.10 65 V -1 -1 -2 -2 -2 -1 1 -3 -2 2 1 1 0 -1 -2 -2 -1 -3 -2 2 0 0 0 0 0 0 14 0 0 22 15 17 0 0 0 0 0 0 0 32 0.17 0.04 66 A 2 -2 -1 -1 -2 -1 1 -1 3 -2 -1 -1 -1 3 -2 0 -1 -2 1 -1 41 0 0 0 0 0 17 0 16 0 0 0 0 26 0 0 0 0 0 0 0.26 0.06 67 R 0 2 0 -1 -2 0 0 -2 -1 -2 -2 2 -1 -3 -1 2 3 -3 -2 -1 0 15 0 0 0 0 0 0 0 0 0 26 0 0 0 21 38 0 0 0 0.36 0.06 68 G 0 -3 -1 -2 -3 -2 -1 6 -2 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 6 94 0 0 0 0 0 0 0 0 0 0 0 0 1.16 0.09 69 R 1 4 -1 -2 -3 1 0 -2 -1 -3 -3 4 -2 -3 -2 0 -1 -3 -2 -2 19 33 0 0 0 0 0 0 0 0 0 49 0 0 0 0 0 0 0 0 0.50 0.07 70 W -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 6 6 -2 0 0 0 0 0 0 0 0 6 0 1 0 0 13 0 0 0 15 60 0 0.93 0.08 71 P 0 0 0 -1 -1 2 0 -1 -1 -1 -1 1 -1 -1 3 0 1 -1 -1 0 4 2 2 3 1 15 3 3 1 2 4 9 1 2 17 3 17 1 2 8 0.19 0.01 72 P 0 -1 -1 0 -2 0 1 -1 -1 -1 -1 0 -1 -2 5 0 -1 -1 -1 -1 4 2 2 3 1 2 16 3 1 2 4 3 1 2 42 3 3 1 2 3 0.59 0.02 73 S 0 0 0 0 -1 0 0 2 0 -1 -1 0 -1 -1 0 1 0 -1 -1 -1 6 4 3 4 1 3 5 19 2 4 6 4 2 3 4 20 4 1 2 5 0.08 0.00 74 S 0 0 1 1 -1 0 0 0 0 0 -1 0 0 -1 0 1 1 -1 -1 0 5 3 11 9 1 3 4 5 1 3 6 4 1 2 3 11 14 1 2 11 0.05 0.00 75 R -1 2 0 1 -1 0 1 -1 -1 -1 0 1 -1 -1 -1 0 0 -1 -1 -1 3 17 2 10 1 2 13 3 1 2 12 13 1 2 2 3 9 1 1 3 0.10 0.01 76 G 0 -1 0 1 -1 0 1 2 -1 -1 -1 0 -1 -2 2 0 -1 -1 -1 -1 9 2 2 10 1 2 11 26 1 2 4 2 1 2 10 3 2 1 1 8 0.17 0.01 77 G 0 -2 -1 -1 -2 -1 -1 4 -2 -2 -2 -1 -2 -2 3 0 -1 -2 -2 -2 2 1 1 2 1 1 2 58 1 1 3 2 1 1 17 2 2 0 1 2 0.58 0.04 78 G -1 0 -1 1 -2 0 1 0 -1 0 -1 1 -1 -2 3 0 -1 -2 -1 0 2 6 1 9 1 1 12 9 1 10 3 16 1 1 16 2 2 0 1 8 0.16 0.01 79 P -1 0 0 4 -2 0 1 -1 -1 -2 -2 1 -2 -2 3 0 -1 -2 -2 -2 3 2 2 34 1 1 10 3 1 2 3 13 1 1 16 2 2 0 1 2 0.34 0.02 80 P 0 1 0 1 -2 0 1 -1 2 -2 -2 3 -1 -2 2 0 -1 -2 -1 -1 11 2 2 7 1 2 8 3 7 2 3 35 1 1 9 3 2 0 1 2 0.17 0.02 81 P -1 -1 -1 -1 -2 0 1 -1 -1 -2 -2 1 -2 -2 6 -1 -1 -2 -2 -2 2 2 1 2 1 1 10 2 1 2 3 13 1 1 52 2 2 0 1 2 0.83 0.04 82 E 0 -1 0 5 -2 0 2 -1 -1 -2 -2 0 -2 -2 -1 0 -1 -2 -2 -2 10 1 1 51 0 1 20 2 1 1 2 1 1 1 1 2 1 0 1 2 0.47 0.04 83 A 1 -2 -2 -2 -2 -1 -2 2 -2 0 0 -1 -1 -2 4 -1 -1 -2 -2 1 16 1 1 1 0 1 1 19 0 1 15 1 0 1 25 1 1 0 0 16 0.32 0.03 84 E -1 0 1 3 -3 0 2 -1 -1 -3 -3 1 -2 -3 4 0 -1 -3 -2 -2 1 1 8 22 0 1 16 1 0 1 1 17 0 1 23 6 1 0 0 1 0.45 0.03 85 T 0 1 -1 -1 -1 0 1 -2 -1 0 -1 0 -1 -2 -1 1 4 -2 -2 0 8 9 1 1 0 1 11 1 0 7 1 6 0 1 1 1 51 0 0 1 0.24 0.04 86 A 1 1 0 0 -1 0 1 1 -1 -1 -1 0 -1 -1 0 0 0 -1 -1 -1 26 11 3 3 1 2 11 11 1 3 5 3 1 2 3 4 3 1 2 4 0.08 0.00 87 E 0 0 0 2 -1 1 2 -1 2 -1 -1 0 -1 -1 0 0 0 -1 -1 -1 4 3 3 20 1 2 23 4 8 3 5 3 1 2 3 4 3 1 2 4 0.16 0.01 88 R 0 2 -1 -1 -1 0 0 -1 -1 -1 -1 0 -1 -1 4 0 0 -1 -1 -1 4 18 3 3 1 2 4 4 1 3 5 3 1 2 32 4 3 1 2 4 0.38 0.01 89 A 3 1 -1 -1 -1 0 0 0 -1 -1 -1 0 -1 -1 0 1 0 -1 -1 0 52 10 2 2 1 2 3 3 1 2 4 2 1 2 2 3 3 1 1 3 0.16 0.02 90 G 0 0 0 -1 -1 0 0 2 -1 0 -1 2 -1 -1 -1 0 0 -1 -1 0 3 2 2 2 1 2 3 18 1 2 4 27 1 2 2 3 7 1 1 15 0.08 0.01 91 W -3 -4 -5 -5 -3 -3 -4 -3 -3 -3 -3 -4 -2 0 -5 -4 -3 11 1 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 3.05 0.18 92 K -1 2 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -2 -1 -1 -4 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.84 0.11 93 T 2 2 -1 -2 -1 -1 -1 -1 -2 -2 -2 0 -1 -3 -2 1 4 -3 -2 -1 34 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 48 0 0 0 0.36 0.07 94 N -2 3 6 0 -3 1 0 -1 0 -4 -3 0 -2 -3 -2 0 -1 -4 -2 -3 0 26 67 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.72 0.09 95 F -2 -3 -4 -4 -2 -3 -4 -4 -2 0 3 -3 1 5 -4 -3 -2 0 2 0 0 0 0 0 0 0 0 0 0 0 43 0 0 57 0 0 0 0 0 0 0.65 0.08 96 R -2 7 -1 -2 -4 0 -1 -3 -1 -4 -3 2 -2 -3 -3 -1 -2 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.11 0.12 97 C -1 -3 -2 -3 9 -3 -3 -3 -3 -2 -2 -3 -2 -3 -3 1 -1 -3 -3 -2 0 0 0 0 81 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 1.38 0.12 98 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 -1 -3 -2 -1 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.66 0.10 99 L -2 -2 -4 -4 -2 -2 -3 -4 -3 1 4 -3 4 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 84 0 16 0 0 0 0 0 0 0 0.59 0.08 100 R -2 2 6 0 -3 0 -1 -1 3 -4 -4 0 -3 -3 -3 0 -1 -4 -2 -3 0 14 78 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0.81 0.10 101 S 0 3 0 -1 -2 0 0 -1 -1 -3 -3 4 -2 -3 -1 3 0 -3 -2 -2 0 19 0 0 0 0 0 0 0 0 0 43 0 0 0 38 0 0 0 0 0.45 0.07 102 T 0 0 0 -1 -2 0 -1 -1 -2 -1 0 2 -1 -2 -1 3 2 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 16 19 0 0 0 43 22 0 0 0 0.25 0.05 103 R -1 3 1 0 -3 0 2 0 2 -3 -3 0 -2 -3 4 1 -1 -3 -2 -3 0 24 8 0 0 0 19 8 7 0 0 0 0 0 21 13 0 0 0 0 0.42 0.04 104 R -1 1 0 4 -3 0 2 -1 -1 -2 -2 0 0 -3 -2 -1 -1 -3 -2 -1 5 15 0 40 0 0 20 5 0 0 0 0 7 0 0 0 0 0 0 9 0.34 0.05 105 F -2 -3 -4 -4 -2 -3 -4 -4 -2 2 2 -3 0 6 -4 -3 -2 0 2 0 0 0 0 0 0 0 0 0 0 16 19 0 0 65 0 0 0 0 0 0 0.65 0.07 106 V -1 3 1 0 -3 1 3 -2 -1 0 -1 1 1 -2 -2 -1 -1 -3 -2 0 0 29 7 0 0 0 36 0 0 8 0 6 7 0 0 0 0 0 0 7 0.30 0.05 107 M -2 -1 -2 -1 -2 0 3 -3 -2 0 3 -1 2 -1 -2 -2 -1 -2 -2 0 0 0 0 0 0 0 42 0 0 0 51 0 7 0 0 0 0 0 0 0 0.34 0.06 108 L 1 0 -3 -3 -1 -2 -2 -2 -3 2 2 -1 2 -1 -2 -1 -1 -3 -2 2 19 8 0 0 0 0 0 0 0 10 22 0 7 0 0 0 0 0 0 34 0.19 0.03 109 R 0 1 -1 0 -3 2 3 -2 0 -2 -2 2 -1 -1 -2 -1 0 -1 3 -1 5 7 0 0 0 8 34 0 0 0 0 16 0 0 0 0 5 0 17 8 0.27 0.04 110 D -2 1 1 6 -4 0 2 -2 -1 -4 -4 0 -3 -4 -2 -1 -2 -4 -3 -4 0 13 0 79 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0.93 0.09 111 N -1 3 2 -1 -3 1 -1 3 2 -4 -3 1 -2 -3 -2 0 -1 -3 -2 -3 0 25 19 0 0 5 0 30 10 0 0 11 0 0 0 0 0 0 0 0 0.40 0.04 112 S 0 1 0 -1 -2 0 -1 -1 -1 -3 -3 0 -2 -3 2 4 1 -3 -2 -2 0 13 0 0 0 0 0 0 0 0 0 0 0 0 10 70 7 0 0 0 0.49 0.08 113 G -1 2 -1 -1 -3 2 0 1 -1 -2 -2 3 2 -3 -2 -1 -1 -3 -2 -2 0 13 0 0 0 17 0 16 0 0 0 40 14 0 0 0 0 0 0 0 0.31 0.04 114 D -2 -2 1 6 2 -1 2 -2 -2 -3 -4 -1 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 82 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0.92 0.07 115 P -1 -2 0 -2 -2 -2 -2 -2 -2 1 -1 -2 -1 -2 6 0 -1 -4 -3 1 0 0 9 0 0 0 0 0 0 17 0 0 0 0 55 6 0 0 0 14 0.89 0.05 116 A 1 -1 -1 1 -2 0 -1 -1 2 -1 -1 -1 1 -1 2 1 0 -2 1 0 22 0 0 9 0 6 0 0 11 0 0 0 9 0 13 17 0 0 5 9 0.17 0.02 117 D -2 -1 2 5 -4 2 3 -2 -1 -3 -4 0 -3 -4 -2 0 -1 -4 -3 -3 0 0 9 58 0 13 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0.72 0.05 118 P -1 -3 -3 -2 -3 -2 -2 -3 -3 -3 -3 -2 -3 -4 8 -1 -2 -4 -4 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.25 0.10 119 H -2 -1 -1 -2 -3 -1 -1 -3 7 -2 -2 -2 -1 1 -3 -2 -2 0 5 0 0 0 0 0 0 0 0 0 47 0 0 0 0 0 0 0 0 0 44 9 0.77 0.08 120 K -1 2 -1 -1 -4 1 0 -2 -1 -3 -3 6 -2 -4 -1 -1 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.76 0.09 121 V -1 -3 -3 -4 -1 -3 -3 -4 -4 3 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 32 0 0 0 0 0 0 0 0 0 68 0.48 0.06 122 Y -2 -2 -3 -4 -3 -2 -3 -4 1 -2 -2 -2 -2 3 -4 -2 -2 2 8 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 1.28 0.11 123 A 1 3 -1 0 -3 3 3 -2 0 -3 -2 1 -1 -3 -1 0 -1 -3 -2 -2 17 24 0 0 0 16 38 0 0 0 1 0 0 0 0 0 0 0 0 0 0.39 0.04 124 L -1 -3 -3 -3 -1 -2 -3 -3 -2 3 2 -3 1 3 -3 -2 -1 -1 0 2 1 0 0 0 0 0 0 0 0 24 24 0 0 23 0 0 0 0 0 24 0.28 0.03 125 S 2 -1 -1 -1 -1 -1 -1 -1 -1 0 -1 -1 0 -1 -1 2 0 -2 -1 2 20 1 1 1 0 1 1 1 0 1 2 1 0 1 1 33 1 0 1 32 0.13 0.01 126 R 0 3 0 -1 -2 0 0 -1 -1 -2 -2 1 -1 -2 3 1 0 -2 -1 -1 3 33 2 2 1 1 2 3 1 2 3 2 1 1 17 21 2 0 1 2 0.28 0.01 127 E -1 -1 0 1 -3 1 4 2 -1 -3 -3 0 -2 -3 -1 0 -1 -2 -2 -2 1 1 1 1 0 1 67 20 0 1 1 1 0 1 1 1 1 0 0 1 0.46 0.03 128 L 0 -2 -2 -2 -1 -2 -2 1 -2 1 2 -2 1 -1 -2 -1 -1 -2 -1 2 1 1 1 1 0 1 1 16 0 1 33 1 0 1 1 1 1 0 0 39 0.14 0.01 129 C 1 -2 -2 -2 6 -2 -2 2 -2 -2 -2 -1 -2 -2 3 0 -1 -2 -2 -1 16 1 1 1 35 1 1 18 0 1 1 1 0 1 19 1 1 0 0 1 0.48 0.02 130 W 0 0 2 0 -1 0 0 -1 0 -2 -2 1 -1 -1 -1 1 0 5 0 -1 3 2 20 2 1 1 2 3 1 2 3 17 1 1 2 19 2 15 1 2 0.25 0.01 131 R 0 2 0 2 -2 0 0 -1 -1 -2 -2 2 -1 -2 -1 1 1 -2 -2 -2 1 16 1 19 0 1 1 1 0 1 1 16 0 1 1 20 17 0 0 1 0.22 0.01 132 E -1 2 2 0 -2 0 1 -1 0 0 -1 0 -1 -2 -1 0 0 -2 -1 0 2 20 21 2 1 1 17 2 1 2 3 2 1 1 2 2 2 0 1 19 0.12 0.01 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0.54 0.02 142 E 0 -1 -1 0 -1 0 2 -2 -1 0 -1 0 -1 -2 -1 1 0 -2 -1 2 1 1 1 1 0 1 31 1 0 1 1 1 0 1 1 20 1 0 0 36 0.14 0.02 143 A 2 -1 0 2 -1 0 2 -1 -1 -2 -2 0 -1 -2 -1 1 0 -2 -2 -1 35 1 1 16 0 1 20 1 0 1 1 1 0 1 1 18 1 0 0 1 0.24 0.01 144 P -1 -1 0 2 -2 -1 0 2 -1 -1 0 -1 -1 -1 3 0 -1 -2 -2 -1 2 2 1 21 1 1 2 21 1 2 19 2 1 1 17 2 2 0 1 2 0.21 0.01 145 A 2 -1 2 0 -1 0 0 0 -1 -1 -1 0 -1 -2 -1 2 0 -2 -1 -1 36 2 21 2 1 1 2 2 1 2 3 2 1 1 2 19 2 0 1 2 0.18 0.01 146 A 2 -1 2 -1 -1 -1 -1 0 -1 0 1 -1 0 -1 -1 0 0 -2 -1 0 37 2 18 2 1 1 2 2 1 2 21 2 1 1 2 2 2 0 1 2 0.09 0.01 147 V 1 0 -1 0 -1 2 2 -1 -1 0 -1 0 0 -2 -1 0 0 -2 -1 1 19 2 1 2 1 20 21 2 1 2 3 2 1 1 2 2 2 0 1 17 0.13 0.01 148 P -1 0 -1 0 -2 2 2 -1 -1 -1 0 0 0 -1 3 0 -1 -2 -1 -1 2 2 1 2 1 20 21 2 1 2 19 2 1 1 17 2 2 0 1 2 0.23 0.01 149 P -1 0 -1 0 -2 2 2 -1 -1 -2 -2 0 -1 -2 5 0 -1 -2 -1 -2 2 2 1 2 1 20 21 2 1 2 3 2 1 1 33 2 2 0 1 2 0.53 0.01 150 P -1 -2 -1 -1 -3 0 2 -2 -2 -3 -3 -1 -2 -3 6 0 1 -4 -3 -2 0 0 0 0 0 0 19 0 0 0 0 0 0 0 64 0 17 0 0 0 1.20 0.04 151 Q -1 1 0 0 -3 6 3 -2 0 -3 -3 1 -1 -3 -2 0 -1 -2 -2 -3 0 0 0 0 0 85 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.05 152 G -1 -1 -1 -2 -2 -1 -1 4 -2 -1 1 1 2 -2 -2 -1 -1 -2 -2 -1 0 0 0 0 0 0 0 47 0 0 19 19 15 0 0 0 0 0 0 0 0.30 0.02 153 G 1 -2 -1 -2 -1 -1 -2 1 -2 1 1 -1 2 -1 -2 1 0 -2 -2 1 15 0 0 0 0 0 0 15 0 0 19 0 19 0 0 15 0 0 0 17 0.12 0.01 154 P -1 -1 -2 -2 -2 -1 -1 -2 -2 0 2 1 2 -1 3 0 -1 -2 -2 0 0 0 0 0 0 0 0 0 0 0 38 15 15 0 15 17 0 0 0 0 0.20 0.02 155 P -1 -1 2 -1 -3 0 -1 -2 -1 -3 -3 1 -2 -3 6 1 0 -4 -3 -3 0 0 19 0 0 0 0 0 0 0 0 15 0 0 51 15 0 0 0 0 0.90 0.03 156 G -1 -2 0 -1 -3 -1 -1 5 5 -4 -4 -1 -2 -3 -2 -1 -2 -3 -1 -3 0 0 0 0 0 0 0 66 34 0 0 0 0 0 0 0 0 0 0 0 0.76 0.04 157 P 1 -1 0 -1 -2 0 -1 -1 3 -2 -2 -1 -1 -2 4 1 0 -2 -1 -2 17 1 1 1 0 1 1 1 19 1 2 1 0 1 31 18 1 0 1 1 0.47 0.02 158 F -1 -2 -1 2 -2 -1 -1 -2 0 -1 -1 -1 -1 4 -2 -1 1 0 3 -1 2 1 1 20 0 1 1 1 0 1 2 1 0 32 1 1 16 0 16 1 0.21 0.01 159 L -1 -2 -3 -3 -1 -2 -3 -3 -3 1 4 -2 2 0 -3 -2 1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 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20 1 1 16 1 1 1 0 1 1 20 17 0 0 1 0.21 0.01 169 P -1 -2 -1 -1 -2 -1 -1 -2 -2 -2 -2 -1 -2 -3 7 0 1 -3 -2 -2 1 1 1 1 0 1 1 1 0 1 1 1 0 1 67 1 20 0 0 1 1.20 0.03 170 G 0 -1 0 0 -2 0 1 3 0 -2 -2 -1 -2 -1 -1 1 -1 -1 2 -2 1 1 1 1 0 1 20 35 0 1 1 1 0 1 1 18 1 0 16 1 0.27 0.01 171 P -1 -2 -2 -2 -3 -2 -2 2 -2 -3 -3 -1 -3 -4 7 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 19 0 0 0 0 0 0 81 0 0 0 0 0 1.64 0.05 172 L 1 -2 -3 -3 -1 -2 -2 -2 -1 1 2 -2 2 0 -2 -1 -1 -1 2 1 19 0 0 0 0 0 0 0 0 0 31 0 15 0 0 0 0 0 15 19 0.18 0.02 173 P 1 -2 -2 -2 -2 -1 -2 -2 -2 0 1 -1 2 -1 4 0 1 -3 -2 0 19 0 0 0 0 0 0 0 0 0 17 0 19 0 30 0 15 0 0 0 0.41 0.02 174 A 4 -1 -1 -1 -1 -1 -1 0 -2 -2 -2 -1 -1 -2 -1 3 0 -3 -2 -1 68 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32 0 0 0 0 0.40 0.03 175 P 1 -2 -2 -1 -2 -1 -1 -1 -2 -2 -2 -1 -2 -3 7 0 -1 -3 -2 -2 20 1 1 1 0 1 1 1 0 1 1 1 0 1 66 1 1 0 1 1 1.16 0.03 176 A 3 -1 -1 -2 -1 -1 -1 -1 0 -1 -1 -1 -1 1 -1 0 -1 0 4 -1 50 1 1 1 0 1 1 1 0 1 1 1 0 1 1 1 1 0 35 1 0.27 0.02 177 G 0 -1 0 -1 -1 2 0 2 -1 -1 0 0 0 -2 -1 2 0 -2 -1 -1 1 1 1 1 0 16 1 16 0 1 20 1 0 1 1 37 1 0 0 1 0.14 0.01 178 D -1 -1 0 3 -2 2 0 -2 -1 -1 1 0 0 -2 -1 0 1 -2 -2 -1 1 1 1 32 0 16 1 1 0 1 21 1 0 1 1 1 20 0 0 1 0.19 0.01 179 K 1 0 -1 -1 -2 2 0 -1 -1 -1 -1 1 -1 -2 3 0 0 -2 -2 0 18 1 1 1 0 19 1 1 0 1 1 16 0 1 20 1 1 0 0 16 0.26 0.01 180 G 0 -1 -1 -2 -2 -1 -1 4 3 -1 -2 1 -1 -2 -2 -1 -1 -3 -1 0 0 0 0 0 0 0 0 47 15 0 0 19 0 0 0 0 0 0 0 19 0.32 0.02 181 D -1 -1 2 5 -3 0 2 -1 -1 -3 -3 0 -3 -3 -2 1 0 -4 -3 -3 0 0 15 50 0 0 19 0 0 0 0 0 0 0 0 15 0 0 0 0 0.58 0.03 182 L -1 -2 -2 -3 -1 -2 -2 -3 -1 1 3 -2 1 1 -2 -2 -1 0 2 0 2 1 1 1 0 1 1 1 0 1 67 1 0 1 1 1 1 0 16 1 0.25 0.02 183 L -1 -2 -2 -2 -1 -1 -2 -2 -2 1 3 -1 3 0 3 -1 -1 -2 -1 0 2 1 1 1 0 1 1 1 0 1 52 1 16 1 16 1 1 0 1 1 0.27 0.02 184 L 1 -1 -2 -2 -1 -1 -2 -2 -2 1 3 -1 3 0 -2 -1 -1 -1 -1 0 17 1 1 1 0 1 1 1 0 1 52 1 16 1 1 1 1 0 1 1 0.18 0.01 185 Q -1 0 0 -1 -2 5 1 -2 0 -2 -2 1 -1 -3 3 0 -1 -2 -1 -2 2 1 1 1 0 66 1 1 0 1 2 1 0 1 16 1 1 0 1 1 0.52 0.03 186 A 1 -1 -1 -1 -1 2 0 -1 -1 0 -1 0 -1 -2 3 1 0 -2 -1 1 16 1 1 1 0 16 1 1 0 1 2 1 0 1 16 20 1 0 1 18 0.21 0.01 187 V 0 -1 -2 -2 -1 -1 -1 -2 -2 2 1 -1 1 0 -1 -1 0 -1 -1 3 3 2 2 2 1 1 2 3 1 2 20 2 1 1 2 2 2 0 1 51 0.12 0.01 188 Q -1 0 0 -1 -2 3 0 -1 3 -1 1 0 0 -1 -1 0 -1 -1 0 -1 3 2 2 2 1 33 2 3 16 2 22 2 1 1 2 2 2 0 1 2 0.15 0.01 189 Q -1 0 2 0 -2 3 1 -1 1 -2 -1 0 -1 0 -1 0 0 0 3 -1 3 2 17 2 1 35 2 3 1 2 3 2 1 1 2 2 2 0 18 2 0.20 0.01 190 S 0 -1 0 -1 -1 0 0 -1 4 -2 -1 0 -1 0 -1 2 0 0 3 -1 3 2 2 2 1 1 2 3 19 2 3 2 1 1 2 34 2 0 16 2 0.18 0.01 191 C 0 -1 -1 -1 6 -1 -1 -1 -1 0 0 -1 2 -1 -1 0 0 -1 -1 0 4 3 2 3 35 2 3 4 1 3 5 3 16 2 3 4 3 1 2 3 0.22 0.01 192 L -1 -1 2 0 -1 0 -1 -1 0 0 1 0 2 0 -1 0 0 -1 -1 0 4 3 21 3 1 2 3 4 1 3 20 3 16 2 3 4 3 1 2 3 0.05 0.00 193 A 1 -1 -1 -1 -1 -1 -1 -1 -1 1 0 -1 0 -1 3 0 0 -1 -1 0 19 3 2 3 1 2 3 4 1 21 5 3 1 2 18 4 3 1 2 3 0.14 0.00 194 D 0 -1 0 2 -1 0 0 0 -1 -1 -1 0 -1 -1 3 1 0 -1 -1 -1 4 3 2 18 1 2 3 4 1 3 5 3 1 2 18 22 3 1 2 3 0.22 0.00 195 H 1 0 0 -1 -1 0 0 -1 6 -2 -2 -1 -1 -1 -1 0 -1 -1 1 -1 21 2 2 2 1 1 2 3 48 2 3 2 1 1 2 2 2 0 1 2 0.31 0.02 196 L -1 -1 -1 -1 -1 -1 -1 -1 -1 2 2 -1 1 0 -1 -1 0 -1 -1 1 4 3 2 3 1 2 3 4 1 19 38 3 1 2 3 4 3 1 2 3 0.07 0.00 197 L -1 -1 -1 -1 -1 -1 -1 -1 -1 1 3 -1 1 0 -1 -1 0 -1 -1 0 4 3 2 3 1 2 3 4 1 3 51 3 1 2 3 4 3 1 2 3 0.09 0.00 198 T -1 -1 1 4 -2 0 2 -1 -1 -2 -2 0 -2 -2 -1 0 1 -3 -2 -2 1 1 1 51 0 1 18 1 0 1 2 1 0 1 1 1 16 0 1 1 0.44 0.02 199 A 1 3 -1 -1 -1 0 -1 -1 -1 0 -1 0 -1 -2 -1 1 0 -2 -1 1 16 31 1 1 0 1 1 1 0 1 2 1 0 1 1 18 1 0 1 21 0.14 0.01 200 S 0 0 0 0 -2 1 2 -1 -1 -2 -2 2 -1 -2 -1 3 0 -2 -1 -2 1 1 1 1 0 1 18 1 0 1 2 20 0 1 1 47 1 0 1 1 0.26 0.02 201 W -1 -2 -2 -2 -2 -1 -2 -2 -2 -2 -2 -2 -1 0 -2 1 -1 10 1 -2 1 1 1 1 0 1 1 1 0 1 2 1 0 1 1 18 1 65 1 1 1.35 0.04 202 G 0 1 -1 -1 -2 -1 -1 4 -1 -3 -3 0 -2 -3 3 0 -1 -2 -2 -2 1 16 1 1 0 1 1 51 0 1 1 1 0 1 20 1 1 0 0 1 0.54 0.02 203 A 2 1 -1 -1 -1 0 -1 -1 -1 -2 -2 0 -1 -2 3 1 0 -2 -2 -1 33 16 1 1 0 1 1 1 0 1 1 1 0 1 20 20 1 0 0 1 0.33 0.01 204 D -1 -1 1 4 -2 2 1 -1 -1 -2 -2 0 -1 -3 -1 0 1 -3 -2 -2 1 1 1 47 0 19 1 1 0 1 1 1 0 1 1 1 20 0 0 1 0.40 0.02 205 P -1 -2 -2 -2 -2 -1 -1 -2 -1 -1 1 -1 -1 0 6 -1 -1 -1 2 -1 1 1 1 1 0 1 1 1 0 1 21 1 0 1 51 1 1 0 16 1 0.77 0.02 206 V 0 -1 -1 -2 -1 2 0 -2 -1 1 0 -1 0 -1 -1 0 2 -2 -1 2 1 1 1 1 0 20 1 1 0 1 1 1 0 1 1 1 20 0 0 48 0.14 0.02 207 P -1 -2 -2 -2 -2 -1 -1 -2 -2 -1 0 -1 -1 -2 7 -1 -1 -3 -2 -1 1 1 1 1 0 1 1 1 0 1 20 1 0 1 67 1 1 0 0 1 1.13 0.03 208 T -1 -2 -1 3 -3 -1 0 -2 -2 -3 -3 -1 -2 -2 5 -1 1 6 -1 -2 0 0 0 30 0 0 0 0 0 0 0 0 0 0 36 0 15 19 0 0 0.81 0.03 209 K 1 0 -1 -2 -2 3 0 -2 0 -1 -1 1 -1 -1 -2 0 -1 -1 2 1 19 0 0 0 0 32 0 0 0 0 0 15 0 0 0 0 0 0 15 19 0.17 0.02 210 A 3 -2 -1 -2 -1 -1 -1 -1 3 0 -1 -1 -1 -2 3 0 -1 -3 -1 1 47 0 0 0 0 0 0 0 19 0 0 0 0 0 15 0 0 0 0 19 0.28 0.02 211 P -1 -2 -1 -2 -2 -1 -1 -2 3 -1 0 -1 -1 -2 6 -1 1 -3 -1 -1 0 0 0 0 0 0 0 0 15 0 19 0 0 0 47 0 19 0 0 0 0.72 0.03 212 G 1 -2 -1 2 -2 -1 -1 4 -2 -3 -3 -1 -2 -3 3 0 -1 -3 -3 -2 19 0 0 15 0 0 0 50 0 0 0 0 0 0 15 0 0 0 0 0 0.56 0.02 213 E -1 0 0 3 -3 3 3 -2 0 -3 -3 0 -2 -4 3 0 -1 -3 -2 -3 0 0 0 19 0 32 30 0 0 0 0 0 0 0 19 0 0 0 0 0 0.59 0.03 214 G 1 -2 -1 -1 -2 0 1 1 -2 0 -2 -1 -1 -2 3 1 0 -3 -2 -1 19 0 0 0 0 0 17 15 0 15 0 0 0 0 19 15 0 0 0 0 0.27 0.01 215 Q 1 0 -1 0 -2 3 2 -2 3 -3 -2 0 -1 -3 3 0 -1 -3 -1 -2 19 0 0 0 0 31 19 0 15 0 0 0 0 0 15 0 0 0 0 0 0.41 0.02 216 E -1 -2 0 4 -3 0 2 -2 -1 -3 -3 -1 -2 -1 5 -1 -1 -2 2 -3 0 0 0 35 0 0 15 0 0 0 0 0 0 0 35 0 0 0 15 0 0.70 0.03 217 G 1 2 -1 -1 -2 2 1 3 -1 -3 -3 0 -2 -3 -2 0 -1 -3 -2 -2 19 17 0 0 0 15 15 34 0 0 0 0 0 0 0 0 0 0 0 0 0.34 0.02 218 L -1 -2 -2 -2 4 -2 -2 -2 -2 2 2 -2 1 0 -2 -1 -1 -2 -1 2 2 1 1 1 16 1 1 1 0 16 35 1 0 1 1 1 1 0 1 18 0.20 0.01 219 P -1 -2 -2 -2 -3 -2 -2 -3 -1 -1 0 -2 -1 -1 6 -1 -1 -2 2 -1 0 0 0 0 0 0 0 0 0 0 19 0 0 0 65 0 0 0 17 0 1.13 0.04 220 L -1 -1 2 -1 -2 0 1 -2 0 0 2 -1 2 0 -2 -1 -1 -1 2 0 0 0 19 0 0 0 17 0 0 0 34 0 15 0 0 0 0 0 15 0 0.15 0.02 221 T -1 -1 -1 -1 -2 2 1 -2 -1 -1 0 0 0 -2 3 0 2 -3 -2 -1 0 0 0 0 0 15 17 0 0 0 19 0 0 0 19 0 30 0 0 0 0.30 0.02 222 G -1 -3 -2 -2 4 -2 -3 3 -2 -1 1 -2 -1 2 3 -1 -1 -2 -1 -1 0 0 0 0 15 0 0 34 0 0 19 0 0 15 17 0 0 0 0 0 0.33 0.02 223 A 1 -2 -2 -2 -2 -2 -2 3 -1 -1 -2 -2 -1 -1 3 -1 -1 -1 2 1 15 0 0 0 0 0 0 34 0 0 0 0 0 0 15 0 0 0 17 19 0.30 0.02 224 C 1 -3 -2 -3 6 -2 -2 -2 -3 -1 -1 -2 -1 -3 5 -1 -1 -3 -2 0 17 0 0 0 34 0 0 0 0 0 0 0 0 0 35 0 0 0 0 15 0.70 0.03 225 A 3 1 -1 -2 -1 -1 -1 -1 -2 -1 1 0 0 -2 -1 0 1 -3 -2 0 51 15 0 0 0 0 0 0 0 0 19 0 0 0 0 0 15 0 0 0 0.18 0.02 226 G -1 -2 -1 -1 -2 -1 -1 3 -2 -2 -2 -1 -2 2 5 -1 -1 -2 -1 -2 1 1 1 1 0 1 1 31 0 1 1 1 0 16 39 1 1 0 1 1 0.63 0.02 227 G 0 -1 0 -1 -2 -1 -1 5 -1 -2 -2 -1 -2 -2 -1 0 -1 -2 -2 -2 2 2 1 2 1 1 2 71 1 2 3 2 1 1 2 2 2 0 1 2 0.58 0.02 228 P -1 -1 2 0 -2 -1 -1 -1 -1 -2 -2 -1 -2 -2 6 0 -1 -2 -2 -2 2 2 21 2 1 1 2 2 1 2 3 2 1 1 51 2 2 0 1 2 0.79 0.02 229 G 1 -1 0 0 -1 0 0 3 -1 -1 -1 0 -1 -1 0 0 0 -1 -1 -1 18 3 3 3 1 3 4 31 1 3 5 3 1 2 3 4 4 1 2 4 0.15 0.00 230 L 1 0 1 0 -1 0 0 0 0 0 1 0 0 -1 0 0 0 -1 -1 0 18 3 15 3 1 3 4 4 1 3 19 3 1 2 3 4 4 1 2 4 0.03 0.00 231 P 0 -1 0 2 -1 0 0 -1 -1 -1 -1 0 -1 -1 4 0 0 -1 -1 -1 5 3 3 16 1 3 4 4 1 3 5 3 1 2 30 4 4 1 2 4 0.35 0.00 232 A 2 -1 -1 -1 -1 0 0 0 -1 -1 0 0 0 2 0 0 0 0 0 0 31 3 3 3 1 3 4 4 1 3 5 3 1 16 3 4 4 1 2 4 0.05 0.00 233 G 0 -1 0 0 -1 0 -1 4 -1 -1 -1 0 -1 -1 0 0 0 -1 -1 -1 5 3 3 3 1 3 4 44 1 3 5 3 1 2 3 4 4 1 2 4 0.24 0.00 234 E -1 2 0 1 -2 3 3 -1 0 -2 -2 1 -1 -2 -1 0 -1 -2 -1 -2 2 15 1 2 1 19 42 2 1 1 3 2 1 1 2 2 2 0 1 2 0.33 0.01 235 L -1 -2 -1 -2 -1 -1 -2 1 -2 1 2 -1 1 2 -1 -1 -1 -1 0 1 2 1 1 2 1 1 2 16 1 1 29 2 1 19 2 2 2 0 1 15 0.08 0.01 236 Y -1 -1 -1 -1 -2 2 0 -2 5 -1 0 -1 0 2 -2 -1 -1 0 3 -1 1 1 1 1 0 18 1 1 28 1 14 1 0 14 1 1 1 0 14 1 0.23 0.02 237 G 0 -1 0 2 -2 0 0 1 4 -2 -2 -1 -2 -2 -1 2 0 -2 0 -2 1 1 1 18 0 1 1 15 28 1 1 1 0 1 1 27 1 0 0 1 0.28 0.02 238 W -2 -2 -3 -2 -2 -1 1 -2 -2 -2 -2 -2 -2 0 -3 -2 -2 10 1 -3 1 1 1 1 0 1 14 1 0 1 1 1 0 1 1 1 1 74 0 1 1.65 0.05 239 A 1 0 0 -1 -2 4 1 -1 0 -1 -2 0 -1 -2 -1 1 0 -2 -1 0 12 1 0 1 0 51 1 1 0 1 1 1 0 0 1 18 1 0 0 11 0.30 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-1 -3 -2 -2 16 1 1 1 0 1 18 1 0 1 1 1 0 0 56 1 1 0 0 1 0.96 0.04 276 S 0 -1 4 0 -2 0 0 -1 4 -3 -3 0 -2 -2 -1 2 0 -3 -1 -2 1 1 33 1 0 1 1 1 21 1 1 1 0 0 1 35 1 0 0 1 0.36 0.03 277 A 0 -2 -2 -2 -2 -1 -2 -2 -2 2 0 -1 3 -1 5 -1 -1 -2 -2 0 12 1 1 1 0 1 1 1 0 24 1 1 21 0 33 1 1 0 0 1 0.43 0.03 278 C 1 2 -2 -2 3 -1 -1 -2 -2 0 2 0 0 -1 -2 -1 -1 -2 -1 0 16 24 1 1 12 1 1 1 0 1 39 1 0 0 1 1 1 0 0 1 0.14 0.02 279 T 0 0 -1 -1 -2 0 0 -1 -1 -2 -2 1 -2 -3 5 2 1 -3 -2 -2 1 1 1 1 0 1 1 1 0 1 1 18 0 0 36 24 12 0 0 1 0.58 0.03 280 A 2 2 -1 -2 -1 -1 -1 -1 -1 -1 1 0 0 -1 3 0 -1 -2 -2 -1 35 18 1 1 0 1 1 1 0 1 22 1 0 0 16 1 1 0 0 1 0.20 0.02 281 V 1 -2 -1 -2 -1 -1 -1 -1 -2 0 1 -1 0 -1 3 0 2 -2 -2 1 24 1 1 1 0 1 1 1 0 1 19 1 0 0 16 1 21 0 0 12 0.20 0.02 282 Q -1 -1 -1 2 -2 1 0 -2 -2 0 2 -1 0 -1 3 -1 -1 -2 -2 -1 1 1 1 21 0 12 1 1 0 1 41 1 0 0 16 1 1 0 0 1 0.22 0.02 283 E 2 -1 -1 0 -1 0 2 -1 -1 0 -1 0 -1 -2 -1 0 0 -2 -1 1 39 1 1 1 0 1 25 2 0 1 2 1 0 1 1 1 1 0 1 19 0.15 0.02 284 P -1 1 -1 -1 -2 -1 -1 1 -1 -1 0 -1 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0 -1 -1 -1 -2 -1 2 1 -3 -2 1 46 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21 13 0 0 20 0.26 0.04 471 S 0 1 0 -1 -2 -1 -1 -1 -1 -3 -3 0 -2 -2 -2 4 0 7 -1 -2 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 66 0 21 0 0 0.59 0.06 472 S 1 -1 0 -1 -1 0 -1 -1 -1 -3 -3 -1 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.65 0.08 473 L 1 -2 -3 -3 -1 -2 -3 -3 -3 1 3 -2 1 2 -3 -1 -1 -2 0 0 21 0 0 0 0 0 0 0 0 0 66 0 0 13 0 0 0 0 0 0 0.31 0.04 474 D -2 -1 2 5 -4 0 3 -2 -1 -3 -4 1 -3 -4 -2 0 -1 -4 -3 -3 0 0 13 54 0 0 24 0 0 0 0 9 0 0 0 0 0 0 0 0 0.67 0.05 475 S 1 -1 0 0 -1 0 0 0 -1 -2 -2 0 -1 -2 -1 4 2 -2 -1 -1 2 1 1 1 0 1 2 2 1 1 2 1 1 1 1 68 11 0 1 2 0.34 0.04 476 S 0 -2 3 -1 -2 -1 -1 2 -1 1 -1 -1 -1 -2 -2 1 0 -3 -2 0 0 0 24 0 0 0 0 25 0 21 0 0 0 0 0 20 0 0 0 9 0.21 0.03 477 S 0 2 2 1 -2 0 0 -1 -1 -2 -2 0 -2 -3 -2 2 2 -3 -2 -2 0 21 13 9 0 0 0 0 0 0 0 0 0 0 0 32 24 0 0 0 0.32 0.03 478 L -1 -3 -3 -4 -1 -2 -3 -4 -3 2 3 -3 1 0 -3 -2 -1 -2 -1 3 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 0 50 0.41 0.04 479 S -1 1 0 3 -3 2 1 1 2 -3 -3 0 -2 -3 -2 1 -1 -3 -2 -3 0 13 0 24 0 21 0 10 9 0 0 0 0 0 0 22 0 0 0 0 0.32 0.03 480 L -2 -3 -4 -4 -2 -3 -3 -4 -3 3 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 31 69 0 0 0 0 0 0 0 0 0 0.48 0.05 481 C -1 0 0 -1 5 3 0 -2 5 -3 -2 0 -1 -3 -2 1 -1 -3 -1 -2 0 0 0 0 24 35 0 0 29 0 0 0 0 0 0 12 0 0 0 0 0.48 0.04 482 L -2 -2 1 -2 -2 -2 -3 -3 -3 3 3 -2 1 0 -3 -2 -1 -2 -1 1 0 0 12 0 0 0 0 0 0 49 39 0 0 0 0 0 0 0 0 0 0.30 0.03 483 S 1 -1 0 -1 -1 0 0 -1 -1 -3 -3 -1 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.60 0.06 484 S 0 -1 3 2 -2 1 0 -1 -1 -2 -3 0 -2 -3 -2 2 2 -3 -2 -2 0 0 29 15 0 12 0 0 0 0 0 0 0 0 0 24 20 0 0 0 0.37 0.03 485 A 1 -1 -1 -1 -1 -1 -1 -1 -2 -2 -2 -1 -2 -3 5 3 2 -3 -2 -2 12 0 0 0 0 0 0 0 0 0 0 0 0 0 32 44 12 0 0 0 0.61 0.03 486 N -2 -1 3 3 -3 -1 0 -2 4 0 -2 -1 -1 2 -2 -1 -1 -2 0 -1 0 0 24 29 0 0 0 0 19 12 0 0 0 15 0 0 0 0 0 0 0.30 0.03 487 S 0 -1 2 0 -2 0 0 -1 -1 -2 -2 0 -2 -2 4 2 0 -2 -2 -2 2 1 16 1 0 1 1 1 0 1 2 1 0 1 30 38 1 0 1 1 0.50 0.02 488 L -2 -3 -4 -4 -1 -3 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 20 80 0 0 0 0 0 0 0 0 0 0.49 0.04 489 Y -1 0 -1 -2 -2 -1 -1 -2 0 -1 -1 1 -1 3 -2 1 1 0 4 -1 0 0 0 0 0 0 0 0 0 0 0 21 0 18 0 16 17 0 28 0 0.25 0.02 490 D -2 -1 1 5 -4 0 3 -2 -1 -3 -4 0 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 68 0 0 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.04 491 D -1 0 3 3 -3 3 1 -2 0 -2 0 0 -1 -2 -2 0 -1 -3 -2 -2 0 0 21 28 0 33 0 0 0 0 18 0 0 0 0 0 0 0 0 0 0.33 0.03 492 I -2 -3 -3 -3 -2 -3 -3 -4 -1 4 1 -3 0 1 -3 -2 -1 0 4 2 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 0 33 0 0.41 0.04 493 E -1 0 -1 0 -3 1 3 -2 -1 -1 -2 3 -1 -3 -1 -1 -1 -3 -2 1 0 0 0 0 0 0 45 0 0 0 0 33 0 0 0 0 0 0 0 21 0.33 0.03 494 C 3 -1 -1 -2 4 2 0 -1 3 -2 -2 -1 -1 -2 -1 0 -1 -3 -1 -1 55 0 0 0 14 18 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0.30 0.03 495 F -2 -1 -2 -3 -3 2 -1 -3 1 -1 -1 -1 -1 4 -3 -2 -2 1 6 -2 0 0 0 0 0 21 0 0 0 0 0 0 0 28 0 0 0 0 51 0 0.59 0.04 496 L -2 -2 -2 -3 -2 -2 -2 -4 3 1 4 -2 2 0 -3 -2 -1 -2 -1 0 0 0 0 0 0 0 0 0 18 0 82 0 0 0 0 0 0 0 0 0 0.40 0.03 497 M -1 0 -1 -2 -2 3 0 -2 -1 -1 0 2 4 -2 -2 -1 -1 -2 -2 -1 0 0 0 0 0 33 0 0 0 0 0 21 45 0 0 0 0 0 0 0 0.31 0.04 498 E -1 0 0 4 -4 4 2 -2 0 -3 -3 0 -2 -4 -2 0 -1 -3 -2 -3 0 0 0 47 0 39 14 0 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.04 499 L -1 -2 -3 -3 -1 -2 -3 -3 -3 1 4 -2 2 0 -3 -2 1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 82 0 0 0 0 0 18 0 0 0 0.39 0.03 500 E -1 -1 0 4 -3 0 3 3 -1 -3 -3 0 -3 -3 -2 0 -1 -3 -3 -3 0 0 0 37 0 0 31 32 0 0 0 0 0 0 0 0 0 0 0 0 0.53 0.00 501 Q -1 1 0 0 -3 5 2 -2 0 -3 -2 1 0 -3 -1 0 -1 -2 -1 -2 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.65 0.00 502 P -1 -2 -2 -1 -3 -1 -1 -2 -2 -3 -3 -1 -2 -3 7 -1 -1 -3 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 503 A 4 -1 -1 -2 0 -1 -1 0 -2 -1 -1 -1 -1 -2 -1 1 0 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.00 0.00 K Lambda Standard Ungapped 0.1357 0.3170 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1357 0.3170 PSI Gapped 0.0410 0.2670