PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
572,214 sequences; 207,235,166 total letters
Results from round 1
Query= sp|Q8NAC3|I17RC_HUMAN Interleukin-17 receptor C OS=Homo sapiens
OX=9606 GN=IL17RC PE=1 SV=2
Length=791
Score E
Sequences producing significant alignments: (Bits) Value
sp|Q8NAC3|I17RC_HUMAN Interleukin-17 receptor C OS=Homo sapiens O... 1580 0.0
sp|Q8K4C2|I17RC_MOUSE Interleukin-17 receptor C OS=Mus musculus O... 847 0.0
sp|Q6AZ51|I17RE_RAT Interleukin-17 receptor E OS=Rattus norvegicu... 92.0 7e-18
sp|Q8BH06|I17RE_MOUSE Interleukin-17 receptor E OS=Mus musculus O... 81.3 2e-14
sp|Q6ZVW7|I17EL_HUMAN Interleukin-17 receptor E-like protein OS=H... 72.8 5e-12
sp|Q8NFR9|I17RE_HUMAN Interleukin-17 receptor E OS=Homo sapiens O... 69.7 6e-11
sp|Q60943|I17RA_MOUSE Interleukin-17 receptor A OS=Mus musculus O... 54.3 4e-06
sp|Q96F46|I17RA_HUMAN Interleukin-17 receptor A OS=Homo sapiens O... 54.3 4e-06
sp|P36772|LON_BRECH Lon protease OS=Brevibacillus choshinensis OX... 36.6 0.99
sp|B8FUN4|DNAK_DESHD Chaperone protein DnaK OS=Desulfitobacterium... 35.4 2.5
>sp|Q8NAC3|I17RC_HUMAN Interleukin-17 receptor C OS=Homo sapiens
OX=9606 GN=IL17RC PE=1 SV=2
Length=791
Score = 1580 bits (4092), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 791/791 (100%), Positives = 791/791 (100%), Gaps = 0/791 (0%)
Query 1 MPVPWFLLSLALGRSPVVLSLERLVGPQDATHCSPVSLEPWGDEERLRVQFLAQQSLSLA 60
MPVPWFLLSLALGRSPVVLSLERLVGPQDATHCSPVSLEPWGDEERLRVQFLAQQSLSLA
Sbjct 1 MPVPWFLLSLALGRSPVVLSLERLVGPQDATHCSPVSLEPWGDEERLRVQFLAQQSLSLA 60
Query 61 PVTAATARTALSGLSGADGRREERGRGKSWVCLSLGGSGNTEPQKKGLSCRLWDSDILCL 120
PVTAATARTALSGLSGADGRREERGRGKSWVCLSLGGSGNTEPQKKGLSCRLWDSDILCL
Sbjct 61 PVTAATARTALSGLSGADGRREERGRGKSWVCLSLGGSGNTEPQKKGLSCRLWDSDILCL 120
Query 121 PGDIVPAPGPVLAPTHLQTELVLRCQKETDCDLCLRVAVHLAVHGHWEEPEDEEKFGGAA 180
PGDIVPAPGPVLAPTHLQTELVLRCQKETDCDLCLRVAVHLAVHGHWEEPEDEEKFGGAA
Sbjct 121 PGDIVPAPGPVLAPTHLQTELVLRCQKETDCDLCLRVAVHLAVHGHWEEPEDEEKFGGAA 180
Query 181 DSGVEEPRNASLQAQVVLSFQAYPTARCVLLEVQVPAALVQFGQSVGSVVYDCFEAALGS 240
DSGVEEPRNASLQAQVVLSFQAYPTARCVLLEVQVPAALVQFGQSVGSVVYDCFEAALGS
Sbjct 181 DSGVEEPRNASLQAQVVLSFQAYPTARCVLLEVQVPAALVQFGQSVGSVVYDCFEAALGS 240
Query 241 EVRIWSYTQPRYEKELNHTQQLPDCRGLEVWNSIPSCWALPWLNVSADGDNVHLVLNVSE 300
EVRIWSYTQPRYEKELNHTQQLPDCRGLEVWNSIPSCWALPWLNVSADGDNVHLVLNVSE
Sbjct 241 EVRIWSYTQPRYEKELNHTQQLPDCRGLEVWNSIPSCWALPWLNVSADGDNVHLVLNVSE 300
Query 301 EQHFGLSLYWNQVQGPPKPRWHKNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICP 360
EQHFGLSLYWNQVQGPPKPRWHKNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICP
Sbjct 301 EQHFGLSLYWNQVQGPPKPRWHKNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICP 360
Query 361 FREDPRAHQNLWQAARLQLLTLQSWLLDAPCSLPAEAALCWRAPGGDPCQPLVPPLSWEN 420
FREDPRAHQNLWQAARLQLLTLQSWLLDAPCSLPAEAALCWRAPGGDPCQPLVPPLSWEN
Sbjct 361 FREDPRAHQNLWQAARLQLLTLQSWLLDAPCSLPAEAALCWRAPGGDPCQPLVPPLSWEN 420
Query 421 VTVDKVLEFPLLKGHPNLCVQVNSSEKLQLQECLWADSLGPLKDDVLLLETRGPQDNRSL 480
VTVDKVLEFPLLKGHPNLCVQVNSSEKLQLQECLWADSLGPLKDDVLLLETRGPQDNRSL
Sbjct 421 VTVDKVLEFPLLKGHPNLCVQVNSSEKLQLQECLWADSLGPLKDDVLLLETRGPQDNRSL 480
Query 481 CALEPSGCTSLPSKASTRAARLGEYLLQDLQSGQCLQLWDDDLGALWACPMDKYIHKRWA 540
CALEPSGCTSLPSKASTRAARLGEYLLQDLQSGQCLQLWDDDLGALWACPMDKYIHKRWA
Sbjct 481 CALEPSGCTSLPSKASTRAARLGEYLLQDLQSGQCLQLWDDDLGALWACPMDKYIHKRWA 540
Query 541 LVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADDSGFERL 600
LVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADDSGFERL
Sbjct 541 LVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADDSGFERL 600
Query 601 VGALASALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLLFSPGAVALC 660
VGALASALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLLFSPGAVALC
Sbjct 601 VGALASALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLLFSPGAVALC 660
Query 661 SEWLQDGVSGPGAHGPHDAFRASLSCVLPDFLQGRAPGSYVGACFDRLLHPDAVPALFRT 720
SEWLQDGVSGPGAHGPHDAFRASLSCVLPDFLQGRAPGSYVGACFDRLLHPDAVPALFRT
Sbjct 661 SEWLQDGVSGPGAHGPHDAFRASLSCVLPDFLQGRAPGSYVGACFDRLLHPDAVPALFRT 720
Query 721 VPVFTLPSQLPDFLGALQQPRAPRSGRLQERAEQVSRALQPALDSYFHPPGTPAPGRGVG 780
VPVFTLPSQLPDFLGALQQPRAPRSGRLQERAEQVSRALQPALDSYFHPPGTPAPGRGVG
Sbjct 721 VPVFTLPSQLPDFLGALQQPRAPRSGRLQERAEQVSRALQPALDSYFHPPGTPAPGRGVG 780
Query 781 PGAGPGAGDGT 791
PGAGPGAGDGT
Sbjct 781 PGAGPGAGDGT 791
>sp|Q8K4C2|I17RC_MOUSE Interleukin-17 receptor C OS=Mus musculus
OX=10090 GN=Il17rc PE=1 SV=3
Length=698
Score = 847 bits (2187), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 460/693 (66%), Positives = 523/693 (75%), Gaps = 37/693 (5%)
Query 89 SWVCLSLGGSGN---------TEPQKK-----GLSCRLWDSDILCLPGDIVPAPGPVLAP 134
SW LSL N EPQ GLSC LWD D+LCLPG + APGPVL P
Sbjct 4 SWFLLSLALGRNPVVVSLERLMEPQDTARCSLGLSCHLWDGDVLCLPGSLQSAPGPVLVP 63
Query 135 THLQTELVLRCQKETDCDLCLRVAVHLAVHGHWEEPEDEEKFGGAADSGVEEPRNASLQA 194
T LQTELVLRC ++TDC LC+RV VHLAVHGHW EPE+ G +DS ++E RNASLQA
Sbjct 64 TRLQTELVLRCPQKTDCALCVRVVVHLAVHGHWAEPEE----AGKSDSELQESRNASLQA 119
Query 195 QVVLSFQAYPTARCVLLEVQVPAALVQFGQSVGSVVYDCFEAALGSEVRIWSYTQPRYEK 254
QVVLSFQAYP ARC LLEVQVPA LVQ GQSVGS V+DCFEA+LG+EV+IWSYT+PRY+K
Sbjct 120 QVVLSFQAYPIARCALLEVQVPADLVQPGQSVGSAVFDCFEASLGAEVQIWSYTKPRYQK 179
Query 255 ELNHTQQLPDCRGLEVWNSIPSCWALPWLNVSADGDNVHLVLNVSEEQHFGLSLYWNQVQ 314
ELN TQQLPDCRGLEV +SI SCW LPWLNVS DGDNV L L+VSEEQ F LY V
Sbjct 180 ELNLTQQLPDCRGLEVRDSIQSCWVLPWLNVSTDGDNVLLTLDVSEEQDFSFLLYLRPVP 239
Query 315 GPPKPRWHKNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICPFREDPRAHQNLWQA 374
K W+KNLTGPQ ITLNHTDLVPCLCIQVW LEPDS R CPFREDP AH+NLW
Sbjct 240 DALKSLWYKNLTGPQNITLNHTDLVPCLCIQVWSLEPDSERVEFCPFREDPGAHRNLWHI 299
Query 375 ARLQLLTLQSWLLDAPCSLPAEAALCWRAPGGDPCQPLVPPLSWENVTVDKVLEFPLLKG 434
ARL++L+ W LDAPC LP + LCW+AP PCQPLVPP+ +N TV++ +F L+ G
Sbjct 300 ARLRVLSPGVWQLDAPCCLPGKVTLCWQAPDQSPCQPLVPPVPQKNATVNEPQDFQLVAG 359
Query 435 HPNLCVQVNSSEKLQLQECLWADSLGPLKDDVLLLETRGPQDNRSLCALEPSGCTSLPSK 494
HPNLCVQV++ EK+QLQ CLWADSLGP KDD+LL+E + +N S+CALEPSGCT LPS
Sbjct 360 HPNLCVQVSTWEKVQLQACLWADSLGPFKDDMLLVEMKTGLNNTSVCALEPSGCTPLPSM 419
Query 495 ASTRAARLGEYLLQDLQSGQCLQLW-DDDLGALWACPMDKYIHKRWALVWLACLLFAAAL 553
ASTRAARLGE LLQD +S QC+QLW DD++G+LWACPMDKYIH+RW LVWLACLL AAAL
Sbjct 420 ASTRAARLGEELLQDFRSHQCMQLWNDDNMGSLWACPMDKYIHRRWVLVWLACLLLAAAL 479
Query 554 SLILLLKKDHAKGWLRLLKQDVRSGAAARG-RAALLLYSADDSGFERLVGALASALCQLP 612
LLLKKD K AARG R ALLL+SAD +G+ERLVGALASAL Q+P
Sbjct 480 FFFLLLKKDRRK--------------AARGSRTALLLHSADGAGYERLVGALASALSQMP 525
Query 613 LRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLLFSPGAVALCSEWLQDGVSGPG 672
LRVAVDLWSRRELSA G +AWFH QRR+ LQEGGVV+LLFSP AVA C +WLQ P
Sbjct 526 LRVAVDLWSRRELSAHGALAWFHHQRRRILQEGGVVILLFSPAAVAQCQQWLQLQTVEP- 584
Query 673 AHGPHDAFRASLSCVLPDFLQGRAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPD 732
GPHDA A LSCVLPDFLQGRA G YVG FD LLHPD+VP+ FR P+F+LPSQLP
Sbjct 585 --GPHDALAAWLSCVLPDFLQGRATGRYVGVYFDGLLHPDSVPSPFRVAPLFSLPSQLPA 642
Query 733 FLGALQQPRAPRSGRLQERAEQVSRALQPALDS 765
FL ALQ + +GR +R E+V++AL+ ALDS
Sbjct 643 FLDALQGGCSTSAGRPADRVERVTQALRSALDS 675
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 26/34 (76%), Positives = 29/34 (85%), Gaps = 0/34 (0%)
Query 1 MPVPWFLLSLALGRSPVVLSLERLVGPQDATHCS 34
MPV WFLLSLALGR+PVV+SLERL+ PQD CS
Sbjct 1 MPVSWFLLSLALGRNPVVVSLERLMEPQDTARCS 34
>sp|Q6AZ51|I17RE_RAT Interleukin-17 receptor E OS=Rattus norvegicus
OX=10116 GN=Il17re PE=2 SV=1
Length=637
Score = 92.0 bits (227), Expect = 7e-18, Method: Compositional matrix adjust.
Identities = 117/429 (27%), Positives = 174/429 (41%), Gaps = 70/429 (16%)
Query 323 KNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICPFREDPRAH-QNLWQAARLQLLT 381
K ++G + L + L+PC+CI+ L+ D+VR CPFR P A+ + W++ R +
Sbjct 183 KIVSGGHTVDLPYEFLLPCMCIEASYLQEDTVRHKKCPFRSWPEAYGSDFWKSIRFTDYS 242
Query 382 LQSWLLDA---PCSLPAEAALCWRAPGGDPCQPLVPPLSWENVTVDKVLEFPLLKG---H 435
S ++ A C L EA+LCWR PC+ L N T + + +L+ H
Sbjct 243 QHSQMVMALTLRCPLKLEASLCWRQDPVTPCKIL------PNATAKESEGWYILENVDLH 296
Query 436 PNLCVQVNSSEKLQLQEC--------LWADSLGPLKDDVLLLETRGPQDNRSLCALEP-- 485
P LC + S E EC W S+ ++L + S P
Sbjct 297 PQLCFKF-SFENSSHVECPHQSGSLPSWTVSMDTQAQQLILHFSTRTYATFSAAWSNPGL 355
Query 486 ---SGCTSLPSKASTRAAR--LGEYLLQDLQSGQCLQLWDDDLGALWA---CPMDKYIHK 537
S T + S + T+ + ++ L+ G C+ +W D+ W CP + H
Sbjct 356 GLDSSMTPVYSISQTQGSVPVTLNLIIPFLRQGSCILVWRSDVQFAWKHLLCPDVSHRHL 415
Query 538 RWALVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADDSGF 597
++ L L + L+L + RLL R R LLL++AD
Sbjct 416 GLLILALLGLTTLLGVVLVLFCR--------RLLP------GPGRTRPVLLLHAADSEAQ 461
Query 598 ERLVGALASALCQLPL----RVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLLFS 653
RLVGALA L + L V VDLW ++ GP+ W A R + +E G V+LL
Sbjct 462 RRLVGALAELL-RTALGGGRDVIVDLWEGTHVARIGPLPWLWAARERVAREQGTVLLL-- 518
Query 654 PGAVALCSEWLQDGVSGPGAHGPHDAFRASLSCVLPDFLQGRAPGSYVGACFDRLLHPDA 713
W G S + P A +LSC AP + A F RL
Sbjct 519 ---------WSCAGPSTACSGDPQTASLRTLSCA--------APRQLLLAYFSRLCAKGD 561
Query 714 VPALFRTVP 722
+P R +P
Sbjct 562 IPGPLRALP 570
>sp|Q8BH06|I17RE_MOUSE Interleukin-17 receptor E OS=Mus musculus
OX=10090 GN=Il17re PE=1 SV=1
Length=637
Score = 81.3 bits (199), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 110/431 (26%), Positives = 171/431 (40%), Gaps = 72/431 (17%)
Query 322 HKNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICPFREDPRAH-QNLWQAARLQLL 380
K ++G + L + L+PC+CI+ L+ D+VR CPF+ P A+ + WQ+ R
Sbjct 182 QKIVSGGHTVDLPYEFLLPCMCIEASYLQEDTVRRKKCPFQSWPEAYGSDFWQSIRFTDY 241
Query 381 TLQSWLLDA---PCSLPAEAALCWRAPGGDPCQPLVPPLSWENVTVDKVLEFPLLKG--- 434
+ + ++ A C L EA+LCWR PC+ L N T + + +L+
Sbjct 242 SQHNQMVMALTLRCPLKLEASLCWRQDPLTPCETL------PNATAQESEGWYILENVDL 295
Query 435 HPNLCVQVNSSEKLQLQECLWADSLGPLKDDVLLLETRGPQ-----DNRSLCALEPSGC- 488
HP LC + S E EC G L + ++T+ Q +R+ +
Sbjct 296 HPQLCFKF-SFENSSHVEC--PHQSGSLPSWTVSMDTQAQQLTLHFSSRTYATFSAAWSD 352
Query 489 ------TSLPSKASTRAARLG-----EYLLQDLQSGQCLQLWDDDLGALWA---CPMDKY 534
T +P S + + ++ L+ C+ +W D+ W CP +
Sbjct 353 PGLGPDTPMPPVYSISQTQGSVPVTLDLIIPFLRQENCILVWRSDVHFAWKHVLCPDVSH 412
Query 535 IHKRWALVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADD 594
H L ++ LL G + +L + R R LLL++AD
Sbjct 413 RH--------------LGLLILALLALTALVGVVLVLLGRRLLPGSGRTRPVLLLHAADS 458
Query 595 SGFERLVGALASALCQL---PLRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLL 651
RLVGALA L V VDLW ++ GP+ W A R + +E G V+LL
Sbjct 459 EAQRRLVGALAELLRTALGGGRDVIVDLWEGTHVARIGPLPWLWAARERVAREQGTVLLL 518
Query 652 FSPGAVALCSEWLQDGVSGPGAHGPHDAFRASLSCVLPDFLQGRAPGSYVGACFDRLLHP 711
++ +GP D ASL +L AP + A F RL
Sbjct 519 WN--------------CAGPSTACSGDPQAASLRTLL-----CAAPRPLLLAYFSRLCAK 559
Query 712 DAVPALFRTVP 722
+P R +P
Sbjct 560 GDIPRPLRALP 570
>sp|Q6ZVW7|I17EL_HUMAN Interleukin-17 receptor E-like protein
OS=Homo sapiens OX=9606 GN=IL17REL PE=1 SV=3
Length=507
Score = 72.8 bits (177), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 58/231 (25%), Positives = 102/231 (44%), Gaps = 13/231 (6%)
Query 221 QFGQSVGSVVYDCFEAALGSEVRIWSYTQPRY-EKELNHTQQLPDCRGLEVWNSIPSCWA 279
Q GQ + V + CF ++ + + T P + +L+ + DC +V S+P C A
Sbjct 126 QGGQQL-QVHFGCFAVSVAQHLYVTLRTIPHFCGVQLDQRHLVEDCGEEDVGRSVPDCLA 184
Query 280 LPWLNVSADGDNVHLVLNV-----SEEQHFGLSLYWNQVQGPPKPRWHKNLTGPQIITLN 334
L+ D +++ V S + + L L + P + Q + L
Sbjct 185 GK-LSYWVDRRRKAILVQVPRASGSPDYYLRLCLKRFTCEDAGAPVRVTANSVSQAVFLP 243
Query 335 HTDLVPCLCIQVWPLEPDSVRTNICPFREDPRAHQNLWQAARLQLLTLQSWLLDAPCSLP 394
++ +PCLC++ W PD+VR ICPF D A + LW + Q+ + C +
Sbjct 244 YSQELPCLCLEGWSATPDAVRIQICPFENDTEALEVLWDTVYYHPES-QTLSWEPACPVS 302
Query 395 AEAALCWRAPGGDPCQPLVPPLSWENVTVDKVLEFPLLKGHPNLCVQVNSS 445
+LCWR G C+ L + V + +++PL+ P LC++ ++S
Sbjct 303 GHVSLCWRPGPGAGCR----KLQQSSQLVHRRVQYPLVDTQPQLCLKFSTS 349
>sp|Q8NFR9|I17RE_HUMAN Interleukin-17 receptor E OS=Homo sapiens
OX=9606 GN=IL17RE PE=1 SV=1
Length=667
Score = 69.7 bits (169), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 43/356 (12%)
Query 323 KNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICPFREDPRAH-QNLWQAARLQLLT 381
K ++G + L + L+PCLCI+ L+ D+VR CPF+ P A+ + W++ +
Sbjct 223 KIVSGGHTVELPYEFLLPCLCIEASYLQEDTVRRKKCPFQSWPEAYGSDFWKSVHFTDYS 282
Query 382 LQSWLLDA---PCSLPAEAALCWRAPGGDPCQPLVPPLSWENVTVDKVLEFPLLKGHPNL 438
+ ++ A C L EAALC R C+ L + E+ D + HP L
Sbjct 283 QHTQMVMALTLRCPLKLEAALCQRHDWHTLCKDLPNATARES---DGWYVLEKVDLHPQL 339
Query 439 CVQVNSSEKLQLQEC--------LWADSLGPLKDDVLL-LETRGPQDNRSLCALEPSGCT 489
C + + + EC W S+ ++L +R + +L G
Sbjct 340 CFKFSFGNSSHV-ECPHQTGSLTSWNVSMDTQAQQLILHFSSRMHATFSAAWSLPGLGQD 398
Query 490 SLPSKASTRAARLG------EYLLQDLQSGQCLQLWDDDLGALWA---CPMDKYIHKRWA 540
+L T + G + ++ L+ G C+ +W D+ W CP Y H
Sbjct 399 TLVPPVYTVSQARGSSPVSLDLIIPFLRPGCCVLVWRSDVQFAWKHLLCPDVSYRHLGLL 458
Query 541 LVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADDSGFERL 600
++ L LL + L L ++ + R LLL++AD RL
Sbjct 459 ILALLALLTLLGVVLALTCRRPQS--------------GPGPARPVLLLHAADSEAQRRL 504
Query 601 VGALASALCQLP---LRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLLFS 653
VGALA L V VDLW R ++ GP+ W A R + +E G V+LL+S
Sbjct 505 VGALAELLRAALGGGRDVIVDLWEGRHVARVGPLPWLWAARTRVAREQGTVLLLWS 560
>sp|Q60943|I17RA_MOUSE Interleukin-17 receptor A OS=Mus musculus
OX=10090 GN=Il17ra PE=1 SV=1
Length=864
Score = 54.3 bits (129), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 44/178 (25%), Positives = 73/178 (41%), Gaps = 6/178 (3%)
Query 582 RGRAALLLYSADDSGFERLVGALASALCQ-LPLRVAVDLWSRRELSAQGPVAWFHAQRRQ 640
R R ++YSAD + +V A L VA+DL + +S G + W Q+++
Sbjct 378 RPRKVWIVYSADHPLYVEVVLKFAQFLITACGTEVALDLLEEQVISEVGVMTWVSRQKQE 437
Query 641 TLQEGGVVVLLFSPGAVALCSE---WLQDGVSGPGAH--GPHDAFRASLSCVLPDFLQGR 695
++ +++L S G A W + V H D F A+++ +LPDF +
Sbjct 438 MVESNSKIIILCSRGTQAKWKAILGWAEPAVQLRCDHWKPAGDLFTAAMNMILPDFKRPA 497
Query 696 APGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRLQERAE 753
G+YV F + VP LF + L + + +Q GR+ E
Sbjct 498 CFGTYVVCYFSGICSERDVPDLFNITSRYPLMDRFEEVYFRIQDLEMFEPGRMHHVRE 555
>sp|Q96F46|I17RA_HUMAN Interleukin-17 receptor A OS=Homo sapiens
OX=9606 GN=IL17RA PE=1 SV=2
Length=866
Score = 54.3 bits (129), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 50/195 (26%), Positives = 81/195 (42%), Gaps = 12/195 (6%)
Query 582 RGRAALLLYSADDSGFERLVGALASAL-CQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQ 640
+ R ++YSAD + +V A L VA+DL + +S G + W Q+++
Sbjct 376 KPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAGVMTWVGRQKQE 435
Query 641 TLQEGGVVVLLFSPGAVALCSEWLQDG--VSGPGAHGP--HDAFRASLSCVLPDFLQGRA 696
++ +++L S G A L G V HG D F A+++ +LPDF +
Sbjct 436 MVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFTAAMNMILPDFKRPAC 495
Query 697 PGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRLQERAEQVS 756
G+YV F + VP LF P + L + + +Q + GR+ E
Sbjct 496 FGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLEMFQPGRMHRVGELSG 555
Query 757 RALQPALDSYFHPPG 771
D+Y PG
Sbjct 556 -------DNYLRSPG 563
>sp|P36772|LON_BRECH Lon protease OS=Brevibacillus choshinensis
OX=54911 GN=lon PE=3 SV=1
Length=779
Score = 36.6 bits (83), Expect = 0.99, Method: Compositional matrix adjust.
Identities = 17/61 (28%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Query 249 QPRYEKELNHTQQLPDC--RGLEVWNSIPSCWALPWLNVSADGDNVHLVLNVSEEQHFGL 306
+ + EKEL +++P G + I + +ALPW + D ++ V +E H+GL
Sbjct 267 KAKIEKELERLEKMPSTSAEGSVIRTYIDTLFALPWTKTTEDNLDIKHAEEVLDEDHYGL 326
Query 307 S 307
Sbjct 327 E 327
>sp|B8FUN4|DNAK_DESHD Chaperone protein DnaK OS=Desulfitobacterium
hafniense (strain DSM 10664 / DCB-2) OX=272564 GN=dnaK
PE=3 SV=1
Length=614
Score = 35.4 bits (80), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 24/85 (28%), Positives = 38/85 (45%), Gaps = 18/85 (21%)
Query 723 VFTLPSQLPDFLG------------ALQQPRAPRSGR----LQERAEQVSRALQPALDSY 766
V+ L DF G AL++ + +G ++E+ E V++ L P ++
Sbjct 514 VYQTEKTLKDFEGKIPDNEAEPIKKALEELKTAAAGENIELIKEKTEGVTKVLYPIIEKM 573
Query 767 FHPPGTPAPGRGVG--PGAGPGAGD 789
+ G APG +G PGAG GD
Sbjct 574 YQQTGGAAPGPDMGADPGAGGAQGD 598
Lambda K H a alpha
0.320 0.137 0.444 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 89865574330
Results from round 2
Query= sp|Q8NAC3|I17RC_HUMAN Interleukin-17 receptor C OS=Homo sapiens
OX=9606 GN=IL17RC PE=1 SV=2
Length=791
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|Q8NAC3|I17RC_HUMAN Interleukin-17 receptor C OS=Homo sapiens O... 1177 0.0
sp|Q8K4C2|I17RC_MOUSE Interleukin-17 receptor C OS=Mus musculus O... 928 0.0
sp|Q6AZ51|I17RE_RAT Interleukin-17 receptor E OS=Rattus norvegicu... 423 5e-137
sp|Q8BH06|I17RE_MOUSE Interleukin-17 receptor E OS=Mus musculus O... 409 4e-132
sp|Q8NFR9|I17RE_HUMAN Interleukin-17 receptor E OS=Homo sapiens O... 379 8e-120
sp|Q6ZVW7|I17EL_HUMAN Interleukin-17 receptor E-like protein OS=H... 295 8e-90
sp|Q60943|I17RA_MOUSE Interleukin-17 receptor A OS=Mus musculus O... 252 9e-71
sp|Q96F46|I17RA_HUMAN Interleukin-17 receptor A OS=Homo sapiens O... 252 2e-70
Sequences not found previously or not previously below threshold:
sp|Q8NFM7|I17RD_HUMAN Interleukin-17 receptor D OS=Homo sapiens O... 79.4 7e-14
sp|Q7T2L7|I17RD_CHICK Interleukin-17 receptor D OS=Gallus gallus ... 76.7 4e-13
sp|Q8JZL1|I17RD_MOUSE Interleukin-17 receptor D OS=Mus musculus O... 74.4 2e-12
sp|Q8QHJ9|I17RD_DANRE Interleukin-17 receptor D OS=Danio rerio OX... 71.0 3e-11
sp|Q9NRM6|I17RB_HUMAN Interleukin-17 receptor B OS=Homo sapiens O... 59.4 8e-08
sp|Q9JIP3|I17RB_MOUSE Interleukin-17 receptor B OS=Mus musculus O... 54.8 2e-06
sp|Q5RB44|RM53_PONAB Large ribosomal subunit protein mL53 OS=Pong... 36.3 0.23
sp|Q8NEZ4|KMT2C_HUMAN Histone-lysine N-methyltransferase 2C OS=Ho... 38.2 0.41
sp|Q96EL3|RM53_HUMAN Large ribosomal subunit protein mL53 OS=Homo... 34.0 1.2
sp|Q2HJF1|RM53_BOVIN Large ribosomal subunit protein mL53 OS=Bos ... 34.0 1.5
sp|B1XX60|MNMA_LEPCP tRNA-specific 2-thiouridylase MnmA OS=Leptot... 35.9 1.6
sp|Q8NBZ0|IN80E_HUMAN INO80 complex subunit E OS=Homo sapiens OX=... 35.1 1.9
sp|Q9M156|U72B1_ARATH UDP-glycosyltransferase 72B1 OS=Arabidopsis... 35.5 2.0
sp|Q8BRH4|KMT2C_MOUSE Histone-lysine N-methyltransferase 2C OS=Mu... 35.9 2.2
>sp|Q8NAC3|I17RC_HUMAN Interleukin-17 receptor C OS=Homo sapiens
OX=9606 GN=IL17RC PE=1 SV=2
Length=791
Score = 1177 bits (3045), Expect = 0.0, Method: Composition-based stats.
Identities = 774/774 (100%), Positives = 774/774 (100%), Gaps = 0/774 (0%)
Query 1 MPVPWFLLSLALGRSPVVLSLERLVGPQDATHCSPVSLEPWGDEERLRVQFLAQQSLSLA 60
MPVPWFLLSLALGRSPVVLSLERLVGPQDATHCSPVSLEPWGDEERLRVQFLAQQSLSLA
Sbjct 1 MPVPWFLLSLALGRSPVVLSLERLVGPQDATHCSPVSLEPWGDEERLRVQFLAQQSLSLA 60
Query 61 PVTAATARTALSGLSGADGRREERGRGKSWVCLSLGGSGNTEPQKKGLSCRLWDSDILCL 120
PVTAATARTALSGLSGADGRREERGRGKSWVCLSLGGSGNTEPQKKGLSCRLWDSDILCL
Sbjct 61 PVTAATARTALSGLSGADGRREERGRGKSWVCLSLGGSGNTEPQKKGLSCRLWDSDILCL 120
Query 121 PGDIVPAPGPVLAPTHLQTELVLRCQKETDCDLCLRVAVHLAVHGHWEEPEDEEKFGGAA 180
PGDIVPAPGPVLAPTHLQTELVLRCQKETDCDLCLRVAVHLAVHGHWEEPEDEEKFGGAA
Sbjct 121 PGDIVPAPGPVLAPTHLQTELVLRCQKETDCDLCLRVAVHLAVHGHWEEPEDEEKFGGAA 180
Query 181 DSGVEEPRNASLQAQVVLSFQAYPTARCVLLEVQVPAALVQFGQSVGSVVYDCFEAALGS 240
DSGVEEPRNASLQAQVVLSFQAYPTARCVLLEVQVPAALVQFGQSVGSVVYDCFEAALGS
Sbjct 181 DSGVEEPRNASLQAQVVLSFQAYPTARCVLLEVQVPAALVQFGQSVGSVVYDCFEAALGS 240
Query 241 EVRIWSYTQPRYEKELNHTQQLPDCRGLEVWNSIPSCWALPWLNVSADGDNVHLVLNVSE 300
EVRIWSYTQPRYEKELNHTQQLPDCRGLEVWNSIPSCWALPWLNVSADGDNVHLVLNVSE
Sbjct 241 EVRIWSYTQPRYEKELNHTQQLPDCRGLEVWNSIPSCWALPWLNVSADGDNVHLVLNVSE 300
Query 301 EQHFGLSLYWNQVQGPPKPRWHKNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICP 360
EQHFGLSLYWNQVQGPPKPRWHKNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICP
Sbjct 301 EQHFGLSLYWNQVQGPPKPRWHKNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICP 360
Query 361 FREDPRAHQNLWQAARLQLLTLQSWLLDAPCSLPAEAALCWRAPGGDPCQPLVPPLSWEN 420
FREDPRAHQNLWQAARLQLLTLQSWLLDAPCSLPAEAALCWRAPGGDPCQPLVPPLSWEN
Sbjct 361 FREDPRAHQNLWQAARLQLLTLQSWLLDAPCSLPAEAALCWRAPGGDPCQPLVPPLSWEN 420
Query 421 VTVDKVLEFPLLKGHPNLCVQVNSSEKLQLQECLWADSLGPLKDDVLLLETRGPQDNRSL 480
VTVDKVLEFPLLKGHPNLCVQVNSSEKLQLQECLWADSLGPLKDDVLLLETRGPQDNRSL
Sbjct 421 VTVDKVLEFPLLKGHPNLCVQVNSSEKLQLQECLWADSLGPLKDDVLLLETRGPQDNRSL 480
Query 481 CALEPSGCTSLPSKASTRAARLGEYLLQDLQSGQCLQLWDDDLGALWACPMDKYIHKRWA 540
CALEPSGCTSLPSKASTRAARLGEYLLQDLQSGQCLQLWDDDLGALWACPMDKYIHKRWA
Sbjct 481 CALEPSGCTSLPSKASTRAARLGEYLLQDLQSGQCLQLWDDDLGALWACPMDKYIHKRWA 540
Query 541 LVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADDSGFERL 600
LVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADDSGFERL
Sbjct 541 LVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADDSGFERL 600
Query 601 VGALASALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLLFSPGAVALC 660
VGALASALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLLFSPGAVALC
Sbjct 601 VGALASALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLLFSPGAVALC 660
Query 661 SEWLQDGVSGPGAHGPHDAFRASLSCVLPDFLQGRAPGSYVGACFDRLLHPDAVPALFRT 720
SEWLQDGVSGPGAHGPHDAFRASLSCVLPDFLQGRAPGSYVGACFDRLLHPDAVPALFRT
Sbjct 661 SEWLQDGVSGPGAHGPHDAFRASLSCVLPDFLQGRAPGSYVGACFDRLLHPDAVPALFRT 720
Query 721 VPVFTLPSQLPDFLGALQQPRAPRSGRLQERAEQVSRALQPALDSYFHPPGTPA 774
VPVFTLPSQLPDFLGALQQPRAPRSGRLQERAEQVSRALQPALDSYFHPPGTPA
Sbjct 721 VPVFTLPSQLPDFLGALQQPRAPRSGRLQERAEQVSRALQPALDSYFHPPGTPA 774
>sp|Q8K4C2|I17RC_MOUSE Interleukin-17 receptor C OS=Mus musculus
OX=10090 GN=Il17rc PE=1 SV=3
Length=698
Score = 928 bits (2398), Expect = 0.0, Method: Composition-based stats.
Identities = 459/701 (65%), Positives = 522/701 (74%), Gaps = 35/701 (5%)
Query 89 SWVCLSLGGSGN---------TEPQKK-----GLSCRLWDSDILCLPGDIVPAPGPVLAP 134
SW LSL N EPQ GLSC LWD D+LCLPG + APGPVL P
Sbjct 4 SWFLLSLALGRNPVVVSLERLMEPQDTARCSLGLSCHLWDGDVLCLPGSLQSAPGPVLVP 63
Query 135 THLQTELVLRCQKETDCDLCLRVAVHLAVHGHWEEPEDEEKFGGAADSGVEEPRNASLQA 194
T LQTELVLRC ++TDC LC+RV VHLAVHGHW EPE+ G +DS ++E RNASLQA
Sbjct 64 TRLQTELVLRCPQKTDCALCVRVVVHLAVHGHWAEPEE----AGKSDSELQESRNASLQA 119
Query 195 QVVLSFQAYPTARCVLLEVQVPAALVQFGQSVGSVVYDCFEAALGSEVRIWSYTQPRYEK 254
QVVLSFQAYP ARC LLEVQVPA LVQ GQSVGS V+DCFEA+LG+EV+IWSYT+PRY+K
Sbjct 120 QVVLSFQAYPIARCALLEVQVPADLVQPGQSVGSAVFDCFEASLGAEVQIWSYTKPRYQK 179
Query 255 ELNHTQQLPDCRGLEVWNSIPSCWALPWLNVSADGDNVHLVLNVSEEQHFGLSLYWNQVQ 314
ELN TQQLPDCRGLEV +SI SCW LPWLNVS DGDNV L L+VSEEQ F LY V
Sbjct 180 ELNLTQQLPDCRGLEVRDSIQSCWVLPWLNVSTDGDNVLLTLDVSEEQDFSFLLYLRPVP 239
Query 315 GPPKPRWHKNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICPFREDPRAHQNLWQA 374
K W+KNLTGPQ ITLNHTDLVPCLCIQVW LEPDS R CPFREDP AH+NLW
Sbjct 240 DALKSLWYKNLTGPQNITLNHTDLVPCLCIQVWSLEPDSERVEFCPFREDPGAHRNLWHI 299
Query 375 ARLQLLTLQSWLLDAPCSLPAEAALCWRAPGGDPCQPLVPPLSWENVTVDKVLEFPLLKG 434
ARL++L+ W LDAPC LP + LCW+AP PCQPLVPP+ +N TV++ +F L+ G
Sbjct 300 ARLRVLSPGVWQLDAPCCLPGKVTLCWQAPDQSPCQPLVPPVPQKNATVNEPQDFQLVAG 359
Query 435 HPNLCVQVNSSEKLQLQECLWADSLGPLKDDVLLLETRGPQDNRSLCALEPSGCTSLPSK 494
HPNLCVQV++ EK+QLQ CLWADSLGP KDD+LL+E + +N S+CALEPSGCT LPS
Sbjct 360 HPNLCVQVSTWEKVQLQACLWADSLGPFKDDMLLVEMKTGLNNTSVCALEPSGCTPLPSM 419
Query 495 ASTRAARLGEYLLQDLQSGQCLQLW-DDDLGALWACPMDKYIHKRWALVWLACLLFAAAL 553
ASTRAARLGE LLQD +S QC+QLW DD++G+LWACPMDKYIH+RW LVWLACLL AAAL
Sbjct 420 ASTRAARLGEELLQDFRSHQCMQLWNDDNMGSLWACPMDKYIHRRWVLVWLACLLLAAAL 479
Query 554 SLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADDSGFERLVGALASALCQLPL 613
LLLKKD K AA R ALLL+SAD +G+ERLVGALASAL Q+PL
Sbjct 480 FFFLLLKKDRRK-------------AARGSRTALLLHSADGAGYERLVGALASALSQMPL 526
Query 614 RVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLLFSPGAVALCSEWLQDGVSGPGA 673
RVAVDLWSRRELSA G +AWFH QRR+ LQEGGVV+LLFSP AVA C +WLQ P
Sbjct 527 RVAVDLWSRRELSAHGALAWFHHQRRRILQEGGVVILLFSPAAVAQCQQWLQLQTVEP-- 584
Query 674 HGPHDAFRASLSCVLPDFLQGRAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDF 733
GPHDA A LSCVLPDFLQGRA G YVG FD LLHPD+VP+ FR P+F+LPSQLP F
Sbjct 585 -GPHDALAAWLSCVLPDFLQGRATGRYVGVYFDGLLHPDSVPSPFRVAPLFSLPSQLPAF 643
Query 734 LGALQQPRAPRSGRLQERAEQVSRALQPALDSYFHPPGTPA 774
L ALQ + +GR +R E+V++AL+ ALDS P
Sbjct 644 LDALQGGCSTSAGRPADRVERVTQALRSALDSCTSSSEAPG 684
Score = 67.9 bits (164), Expect = 3e-10, Method: Composition-based stats.
Identities = 26/34 (76%), Positives = 29/34 (85%), Gaps = 0/34 (0%)
Query 1 MPVPWFLLSLALGRSPVVLSLERLVGPQDATHCS 34
MPV WFLLSLALGR+PVV+SLERL+ PQD CS
Sbjct 1 MPVSWFLLSLALGRNPVVVSLERLMEPQDTARCS 34
>sp|Q6AZ51|I17RE_RAT Interleukin-17 receptor E OS=Rattus norvegicus
OX=10116 GN=Il17re PE=2 SV=1
Length=637
Score = 423 bits (1086), Expect = 5e-137, Method: Composition-based stats.
Identities = 116/461 (25%), Positives = 180/461 (39%), Gaps = 70/461 (15%)
Query 292 VHLVLNVSEEQHFGLSLYW-NQVQGPPKPR-WHKNLTGPQIITLNHTDLVPCLCIQVWPL 349
+ + + E + L W + + P K ++G + L + L+PC+CI+ L
Sbjct 150 IRVTIPPGPEANVRLCYQWALECEDMSSPFDTQKIVSGGHTVDLPYEFLLPCMCIEASYL 209
Query 350 EPDSVRTNICPFREDPRAH-QNLWQAARLQLLTLQSWLLDA---PCSLPAEAALCWRAPG 405
+ D+VR CPFR P A+ + W++ R + S ++ A C L EA+LCWR
Sbjct 210 QEDTVRHKKCPFRSWPEAYGSDFWKSIRFTDYSQHSQMVMALTLRCPLKLEASLCWRQDP 269
Query 406 GDPCQPLVPPLSWENVTVDKVLEFPLLKG---HPNLCVQVNSSEKLQLQEC--------L 454
PC+ L N T + + +L+ HP LC + + E EC
Sbjct 270 VTPCKIL------PNATAKESEGWYILENVDLHPQLCFKFS-FENSSHVECPHQSGSLPS 322
Query 455 WADSLGPLKDDVLLLETRGPQDNRSLCALEP-----SGCTSLPSKASTRAA--RLGEYLL 507
W S+ ++L + S P S T + S + T+ + ++
Sbjct 323 WTVSMDTQAQQLILHFSTRTYATFSAAWSNPGLGLDSSMTPVYSISQTQGSVPVTLNLII 382
Query 508 QDLQSGQCLQLWDDDLGALWA---CPMDKYIHKRWALVWLACLLFAAALSLILLLKKDHA 564
L+ G C+ +W D+ W CP + H ++ L L + L+L ++
Sbjct 383 PFLRQGSCILVWRSDVQFAWKHLLCPDVSHRHLGLLILALLGLTTLLGVVLVLFCRR--- 439
Query 565 KGWLRLLKQDVRSGAAARGRAALLLYSADDSGFERLVGALASALCQL---PLRVAVDLWS 621
R R LLL++AD RLVGALA L V VDLW
Sbjct 440 -----------LLPGPGRTRPVLLLHAADSEAQRRLVGALAELLRTALGGGRDVIVDLWE 488
Query 622 RRELSAQGPVAWFHAQRRQTLQEGGVVVLLFSPGAVALCSEWLQDGVSGPGAHGPHDAFR 681
++ GP+ W A R + +E G V+LL W G S + P A
Sbjct 489 GTHVARIGPLPWLWAARERVAREQGTVLLL-----------WSCAGPSTACSGDPQTASL 537
Query 682 ASLSCVLPDFLQGRAPGSYVGACFDRLLHPDAVPALFRTVP 722
+LSC AP + A F RL +P R +P
Sbjct 538 RTLSC--------AAPRQLLLAYFSRLCAKGDIPGPLRALP 570
>sp|Q8BH06|I17RE_MOUSE Interleukin-17 receptor E OS=Mus musculus
OX=10090 GN=Il17re PE=1 SV=1
Length=637
Score = 409 bits (1052), Expect = 4e-132, Method: Composition-based stats.
Identities = 109/458 (24%), Positives = 173/458 (38%), Gaps = 64/458 (14%)
Query 292 VHLVLNVSEEQHFGLSLYW-NQVQGPPKPR-WHKNLTGPQIITLNHTDLVPCLCIQVWPL 349
V + + + L W + + P K ++G + L + L+PC+CI+ L
Sbjct 150 VRVTIPAGPKASVRLCYQWALECEDLSSPFDTQKIVSGGHTVDLPYEFLLPCMCIEASYL 209
Query 350 EPDSVRTNICPFREDPRAH-QNLWQAARLQLLTLQSWLLDA---PCSLPAEAALCWRAPG 405
+ D+VR CPF+ P A+ + WQ+ R + + ++ A C L EA+LCWR
Sbjct 210 QEDTVRRKKCPFQSWPEAYGSDFWQSIRFTDYSQHNQMVMALTLRCPLKLEASLCWRQDP 269
Query 406 GDPCQPLVPPLSWENVTVDKVLEFPLLKGHPNLCVQVNSSEKLQLQEC--------LWAD 457
PC+ L + E+ + + HP LC + + E EC W
Sbjct 270 LTPCETLPNATAQES---EGWYILENVDLHPQLCFKFS-FENSSHVECPHQSGSLPSWTV 325
Query 458 SLGPLKDDVLLLETRGPQDNRSLCALEP--SGCTSLPSKASTRAARLG-----EYLLQDL 510
S+ + L + S +P T +P S + + ++ L
Sbjct 326 SMDTQAQQLTLHFSSRTYATFSAAWSDPGLGPDTPMPPVYSISQTQGSVPVTLDLIIPFL 385
Query 511 QSGQCLQLWDDDLGALWA---CPMDKYIHKRWALVWLACLLFAAALSLILLLKKDHAKGW 567
+ C+ +W D+ W CP + H ++ L G
Sbjct 386 RQENCILVWRSDVHFAWKHVLCPDVSHRHLGLLILALL--------------ALTALVGV 431
Query 568 LRLLKQDVRSGAAARGRAALLLYSADDSGFERLVGALASALCQL---PLRVAVDLWSRRE 624
+ +L + R R LLL++AD RLVGALA L V VDLW
Sbjct 432 VLVLLGRRLLPGSGRTRPVLLLHAADSEAQRRLVGALAELLRTALGGGRDVIVDLWEGTH 491
Query 625 LSAQGPVAWFHAQRRQTLQEGGVVVLLFSPGAVALCSEWLQDGVSGPGAHGPHDAFRASL 684
++ GP+ W A R + +E G V+LL++ +GP D ASL
Sbjct 492 VARIGPLPWLWAARERVAREQGTVLLLWN--------------CAGPSTACSGDPQAASL 537
Query 685 SCVLPDFLQGRAPGSYVGACFDRLLHPDAVPALFRTVP 722
+L AP + A F RL +P R +P
Sbjct 538 RTLL-----CAAPRPLLLAYFSRLCAKGDIPRPLRALP 570
>sp|Q8NFR9|I17RE_HUMAN Interleukin-17 receptor E OS=Homo sapiens
OX=9606 GN=IL17RE PE=1 SV=1
Length=667
Score = 379 bits (972), Expect = 8e-120, Method: Composition-based stats.
Identities = 116/487 (24%), Positives = 183/487 (38%), Gaps = 69/487 (14%)
Query 269 EVWNSIPSC----WALPWLNVSA--DGDNVHLVLNVSEEQHFGLSLYW-NQVQGPPKPR- 320
E W S+P P + + + + ++ E L W + + P
Sbjct 161 ETWESLPRLDSQRHGGPEFSFDLLPEARAIRVTISSGPEVSVRLCHQWALECEELSSPYD 220
Query 321 WHKNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICPFREDPRAH-QNLWQAARLQL 379
K ++G + L + L+PCLCI+ L+ D+VR CPF+ P A+ + W++
Sbjct 221 VQKIVSGGHTVELPYEFLLPCLCIEASYLQEDTVRRKKCPFQSWPEAYGSDFWKSVHFTD 280
Query 380 LTLQSWLLDA---PCSLPAEAALCWRAPGGDPCQPLVPPLSWENVTVDKVLEFPLLKGHP 436
+ + ++ A C L EAALC R C+ L + E+ D + HP
Sbjct 281 YSQHTQMVMALTLRCPLKLEAALCQRHDWHTLCKDLPNATARES---DGWYVLEKVDLHP 337
Query 437 NLCVQVNSSEKLQLQEC--------LWADSLGPLKDDVLLLE-TRGPQDNRSLCALEPSG 487
LC + + EC W S+ ++L +R + +L G
Sbjct 338 QLCFKFSFG-NSSHVECPHQTGSLTSWNVSMDTQAQQLILHFSSRMHATFSAAWSLPGLG 396
Query 488 CTSLPSKASTRAARLG------EYLLQDLQSGQCLQLWDDDLGALWA---CPMDKYIHKR 538
+L T + G + ++ L+ G C+ +W D+ W CP Y H
Sbjct 397 QDTLVPPVYTVSQARGSSPVSLDLIIPFLRPGCCVLVWRSDVQFAWKHLLCPDVSYRHLG 456
Query 539 WALVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADDSGFE 598
++ L LL + L L ++ + R LLL++AD
Sbjct 457 LLILALLALLTLLGVVLALTCRRPQS--------------GPGPARPVLLLHAADSEAQR 502
Query 599 RLVGALASALCQL---PLRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLLFSPG 655
RLVGALA L V VDLW R ++ GP+ W A R + +E G V+LL+S
Sbjct 503 RLVGALAELLRAALGGGRDVIVDLWEGRHVARVGPLPWLWAARTRVAREQGTVLLLWS-- 560
Query 656 AVALCSEWLQDGVSGPGAHGPHDAFRASLSCVLPDFLQGRAPGSYVGACFDRLLHPDAVP 715
G GP D A L +L + + A F RL +P
Sbjct 561 -----------GADLRPVSGP-DPRAAPLLALLHAAPRPL----LLLAYFSRLCAKGDIP 604
Query 716 ALFRTVP 722
R +P
Sbjct 605 PPLRALP 611
>sp|Q6ZVW7|I17EL_HUMAN Interleukin-17 receptor E-like protein
OS=Homo sapiens OX=9606 GN=IL17REL PE=1 SV=3
Length=507
Score = 295 bits (754), Expect = 8e-90, Method: Composition-based stats.
Identities = 76/336 (23%), Positives = 129/336 (38%), Gaps = 38/336 (11%)
Query 221 QFGQSVGSVVYDCFEAALGSEVRIWSYTQPRY-EKELNHTQQLPDCRGLEVWNSIPSCWA 279
Q GQ + V + CF ++ + + T P + +L+ + DC +V S+P C A
Sbjct 126 QGGQQL-QVHFGCFAVSVAQHLYVTLRTIPHFCGVQLDQRHLVEDCGEEDVGRSVPDCLA 184
Query 280 LPWLNVSADGDNVHLVLNV-----SEEQHFGLSLYWNQVQGPPKPRWHKNLTGPQIITLN 334
L+ D +++ V S + + L L + P + Q + L
Sbjct 185 GK-LSYWVDRRRKAILVQVPRASGSPDYYLRLCLKRFTCEDAGAPVRVTANSVSQAVFLP 243
Query 335 HTDLVPCLCIQVWPLEPDSVRTNICPFREDPRAHQNLWQAARLQLLTLQSWLLDAPCSLP 394
++ +PCLC++ W PD+VR ICPF D A + LW + Q+ + C +
Sbjct 244 YSQELPCLCLEGWSATPDAVRIQICPFENDTEALEVLWDTVYYHPES-QTLSWEPACPVS 302
Query 395 AEAALCWRAPGGDPCQPLVPPLSWENVTVDKVLEFPLLKGHPNLCVQVNSSEKL------ 448
+LCWR G C+ L + V + +++PL+ P LC++ ++S
Sbjct 303 GHVSLCWRPGPGAGCR----KLQQSSQLVHRRVQYPLVDTQPQLCLKFSTSWGSWVRCPF 358
Query 449 -QLQECLWADSLGPLKDD---VLLLETRGPQDN------RSLCALEPSGCT----SLPSK 494
Q + W ++ P + + P R L T LPS
Sbjct 359 EQRRFPTWKMTIQPSPTKGHLRVTFFSSSPAHFQVHLCHRRKSQLPACQRTLQASPLPSA 418
Query 495 ASTRAARLGEYLLQDLQ-----SGQCLQLWDDDLGA 525
+ AA L + G C+Q W D+
Sbjct 419 SGDLAAAPAFAFLDLPREEACAPGICIQGWRTDVHF 454
>sp|Q60943|I17RA_MOUSE Interleukin-17 receptor A OS=Mus musculus
OX=10090 GN=Il17ra PE=1 SV=1
Length=864
Score = 252 bits (644), Expect = 9e-71, Method: Composition-based stats.
Identities = 52/247 (21%), Positives = 93/247 (38%), Gaps = 24/247 (10%)
Query 541 LVWLACLLFAAALSLILLLKKDHAKGWLR-----------LLKQDVRSGAAARGRAALLL 589
L+ L +L ++ ++++ G + +L + R R ++
Sbjct 326 LITLIAILLVGSVIVLIICMTWRLSGADQEKHGDDSKINGILPVADLTPPPLRPRKVWIV 385
Query 590 YSADDSGFERLVGALASAL-CQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVV 648
YSAD + +V A L VA+DL + +S G + W Q+++ ++ +
Sbjct 386 YSADHPLYVEVVLKFAQFLITACGTEVALDLLEEQVISEVGVMTWVSRQKQEMVESNSKI 445
Query 649 VLLFSPGAVALCSE---WLQDGVSGPGAH--GPHDAFRASLSCVLPDFLQGRAPGSYVGA 703
++L S G A W + V H D F A+++ +LPDF + G+YV
Sbjct 446 IILCSRGTQAKWKAILGWAEPAVQLRCDHWKPAGDLFTAAMNMILPDFKRPACFGTYVVC 505
Query 704 CFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRLQERAEQVSRALQPAL 763
F + VP LF + L + + +Q GR+ E
Sbjct 506 YFSGICSERDVPDLFNITSRYPLMDRFEEVYFRIQDLEMFEPGRMHHVRELTG------- 558
Query 764 DSYFHPP 770
D+Y P
Sbjct 559 DNYLQSP 565
>sp|Q96F46|I17RA_HUMAN Interleukin-17 receptor A OS=Homo sapiens
OX=9606 GN=IL17RA PE=1 SV=2
Length=866
Score = 252 bits (642), Expect = 2e-70, Method: Composition-based stats.
Identities = 51/206 (25%), Positives = 82/206 (40%), Gaps = 12/206 (6%)
Query 571 LKQDVRSGAAARGRAALLLYSADDSGFERLVGALASAL-CQLPLRVAVDLWSRRELSAQG 629
L + R ++YSAD + +V A L VA+DL + +S G
Sbjct 365 LPAADLIPPPLKPRKVWIIYSADHPLYVDVVLKFAQFLLTACGTEVALDLLEEQAISEAG 424
Query 630 PVAWFHAQRRQTLQEGGVVVLLFSPGAVALCSEWLQDG--VSGPGAHGP--HDAFRASLS 685
+ W Q+++ ++ +++L S G A L G V HG D F A+++
Sbjct 425 VMTWVGRQKQEMVESNSKIIVLCSRGTRAKWQALLGRGAPVRLRCDHGKPVGDLFTAAMN 484
Query 686 CVLPDFLQGRAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRS 745
+LPDF + G+YV F + VP LF P + L + + +Q +
Sbjct 485 MILPDFKRPACFGTYVVCYFSEVSCDGDVPDLFGAAPRYPLMDRFEEVYFRIQDLEMFQP 544
Query 746 GRLQERAEQVSRALQPALDSYFHPPG 771
GR+ E D+Y PG
Sbjct 545 GRMHRVGELSG-------DNYLRSPG 563
>sp|Q8NFM7|I17RD_HUMAN Interleukin-17 receptor D OS=Homo sapiens
OX=9606 GN=IL17RD PE=1 SV=3
Length=739
Score = 79.4 bits (194), Expect = 7e-14, Method: Composition-based stats.
Identities = 48/264 (18%), Positives = 83/264 (31%), Gaps = 34/264 (13%)
Query 523 LGALWACPMDKYIHKRWALVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSGAAA- 581
+ + WA P+ + A+ ++ A A ++ +K + L ++ +
Sbjct 290 VHSPWAGPI-----RAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSTYT 344
Query 582 --------RGRA-ALLLYSA-DDSGFERLVGALASALCQ-LPLRVAVDLWSRRELSAQGP 630
R R L YS+ D +V A L VA+DLW L +G
Sbjct 345 AALPRERLRPRPKVFLCYSSKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQ 404
Query 631 VAWFHAQRRQTLQEGGVVVLLFSPGAVALCSEWLQDGVSGPGAHGPHDAFRASLSCVLPD 690
W Q + E ++++ S G + G G + F ++S +
Sbjct 405 REWV----IQKIHESQFIIVVCSKGMKYFVDKKNYKHKGGGRGSGKGELFLVAVSAIAEK 460
Query 691 FLQG-----RAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRS 745
Q A ++ FD VP + + L LP Q +
Sbjct 461 LRQAKQSSSAALSKFIAVYFD-YSCEGDVPGILDLSTKYRLMDNLP-------QLCSHLH 512
Query 746 GRLQERAEQVSRALQPALDSYFHP 769
R E Q + +YF
Sbjct 513 SRDHGLQEPGQHTRQGSRRNYFRS 536
>sp|Q7T2L7|I17RD_CHICK Interleukin-17 receptor D OS=Gallus gallus
OX=9031 GN=IL17RD PE=2 SV=1
Length=741
Score = 76.7 bits (187), Expect = 4e-13, Method: Composition-based stats.
Identities = 39/234 (17%), Positives = 76/234 (32%), Gaps = 30/234 (13%)
Query 523 LGALWACPMDKYIHKRWALVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSG---A 579
+ + WA P+ + A+ ++ A A ++ +K + L ++
Sbjct 292 VHSPWAGPI-----RAIAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESSESSAYG 346
Query 580 AA------RGRA-ALLLYSA-DDSGFERLVGALASALCQ-LPLRVAVDLWSRRELSAQGP 630
A R R + YS+ D ++ A L VA+DLW ++ +
Sbjct 347 AGLPVERLRPRPKVFICYSSKDCQKHINVIQCFAYFLQDFCGCEVALDLWEDLKICKESQ 406
Query 631 VAWFHAQRRQTLQEGGVVVLLFSPGAV--ALCSEWLQDGVSGPGAHGPHDAFRASLSCVL 688
W + + E ++++ S G W GV+ G + F ++ V
Sbjct 407 KEWLIKK----INESQFIIIVCSKGMKYFVEKKNWKHRGVTK--DTGKGELFLFAVFTVA 460
Query 689 PDFLQGRAPG----SYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQ 738
Q + ++ FD +P + + L LP L
Sbjct 461 EKLRQAKQNSNDLCKFIAVYFD-YSCEGDIPGILDLSTKYKLMDNLPQLYSHLH 513
>sp|Q8JZL1|I17RD_MOUSE Interleukin-17 receptor D OS=Mus musculus
OX=10090 GN=Il17rd PE=1 SV=1
Length=738
Score = 74.4 bits (181), Expect = 2e-12, Method: Composition-based stats.
Identities = 46/267 (17%), Positives = 83/267 (31%), Gaps = 34/267 (13%)
Query 523 LGALWACPMDKYIHKRWALVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSG---A 579
+ + WA P+ + A+ ++ A A ++ +K + L ++ A
Sbjct 290 VQSPWAGPI-----RAVAITVPLVVISAFATLFTVMCRKKQQENIYSHLDEESPESSTYA 344
Query 580 AARGR-------AALLLYS-ADDSGFERLVGALASALCQ-LPLRVAVDLWSRRELSAQGP 630
AA R L YS D +V A L VA+DLW L +G
Sbjct 345 AALPRDRLRPQPKVFLCYSNKDGQNHMNVVQCFAYFLQDFCGCEVALDLWEDFSLCREGQ 404
Query 631 VAWFHAQRRQTLQEGGVVVLLFSPGAVALCSEWLQDGVSGPGAHGPHDAFRASLSCVLPD 690
W ++ + ++++ S G + G + F +++ +
Sbjct 405 REW---AIQKIHESQ-FIIVVCSKGMKYFVDKKNFRHKGGSRGEAQGEFFLVAVAAIAEK 460
Query 691 FLQG-----RAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRA--- 742
Q A ++ FD VP + L LP+ L
Sbjct 461 LRQAKQSSSAALRKFIAVYFD-YSCEGDVPCSLDLSTKYKLMDHLPELCAHLHSGEQEVL 519
Query 743 -PRSGRLQER---AEQVSRALQPALDS 765
G R + R+L A+ +
Sbjct 520 GQHPGHSSRRNYFRSKSGRSLYVAICN 546
>sp|Q8QHJ9|I17RD_DANRE Interleukin-17 receptor D OS=Danio rerio
OX=7955 GN=il17rd PE=1 SV=2
Length=745
Score = 71.0 bits (172), Expect = 3e-11, Method: Composition-based stats.
Identities = 42/254 (17%), Positives = 84/254 (33%), Gaps = 37/254 (15%)
Query 521 DDLGALWACPMDKYIHKRWALVWLACLLFAAALSLILLLKKDHAKGWLRLL-------KQ 573
+ + WA P+ + A+ ++ A A ++ +K + L
Sbjct 287 SQVHSPWAGPI-----RAMAITVPLVIMSAFATLFTVMCRKKQQENIYSHLDEESSESSS 341
Query 574 DVRSGAAARGRA---ALLLYSA-DDSGFERLVGALASALCQ-LPLRVAVDLWSRRELSAQ 628
+ +A R + YS+ D + ++ + A L V++DLW E+ +
Sbjct 342 QTTALSADRPWPRPKIFICYSSRDGAKHLAVIQSFAFFLQDFCGCEVSLDLWEHLEICKE 401
Query 629 GPVAWFHAQRRQTLQEGGVVVLLFSPG-----------AVALCSEWLQDGVSGPGAHGPH 677
G ++W + + E ++ + S G A E ++ + +
Sbjct 402 GQMSWLSRR----IDEAHFIITVCSKGLKHFVEKRHRKGKATSKEKNREPSASDSSSSSR 457
Query 678 DAFRASLSCVLPDFL----QGRAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDF 733
D F + + + + ++ FD H VP P F L QLP
Sbjct 458 DLFIVASAIISEKLKEVHQKSSDLSRFMSVYFD-YSHETDVPTSLSLAPKFKLMDQLPQL 516
Query 734 LGALQQPRAPRSGR 747
L + + R
Sbjct 517 FARLHSRQLSLTDR 530
>sp|Q9NRM6|I17RB_HUMAN Interleukin-17 receptor B OS=Homo sapiens
OX=9606 GN=IL17RB PE=1 SV=2
Length=502
Score = 59.4 bits (142), Expect = 8e-08, Method: Composition-based stats.
Identities = 27/153 (18%), Positives = 48/153 (31%), Gaps = 8/153 (5%)
Query 582 RGRAALLLYSADDSGFERLVGALASALCQ-LPLRVAVDLWSRRELSAQGPVAWFHAQRRQ 640
L++Y ++ F + L V ++ W +++++ GPV W Q+
Sbjct 330 PPIKVLVVYPSE-ICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQK-- 386
Query 641 TLQEGGVVVLLFSPGAVALCSEWLQDGVSGPGAHGPHDAFRASLSCVLPDFLQGRAPGSY 700
+ VV L S ++C G + D F + + D Y
Sbjct 387 --KAADKVVFLLSNDVNSVCDG-TCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKY 443
Query 701 VGACFDRLLHPDAVPALFRTVPVFTLPSQLPDF 733
V F + D P + L F
Sbjct 444 VVVYFREIDTKDDY-NALSVCPKYHLMKDATAF 475
>sp|Q9JIP3|I17RB_MOUSE Interleukin-17 receptor B OS=Mus musculus
OX=10090 GN=Il17rb PE=1 SV=1
Length=499
Score = 54.8 bits (130), Expect = 2e-06, Method: Composition-based stats.
Identities = 30/170 (18%), Positives = 54/170 (32%), Gaps = 10/170 (6%)
Query 585 AALLLYSADDSGFERLVGALASALCQ-LPLRVAVDLWSRRELSAQGPVAWFHAQRRQTLQ 643
L++Y ++ F V L V ++ W +++++ GPV W Q++
Sbjct 330 KVLVVYPSE-ICFHHTVCRFTDFLQNYCRSEVILEKWQKKKIAEMGPVQWLTTQKQ---- 384
Query 644 EGGVVVLLFSPGAVALCSEWLQDGVSGPGAHGPHDAFRASLSCVLPDFLQGRAPGSYVGA 703
VV L LC G D F + + DF Y+
Sbjct 385 AADKVVFLLPSDVPTLCDS-ACGHNEGSARENSQDLFPLAFNLFCSDFSSQTHLHKYLVV 443
Query 704 CFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRLQERAE 753
P + L F L +A +S +++R++
Sbjct 444 YLGGADLKGDY-NALSVCPQYHLMKDATAFHTEL--LKATQSMSVKKRSQ 490
>sp|Q5RB44|RM53_PONAB Large ribosomal subunit protein mL53 OS=Pongo
abelii OX=9601 GN=MRPL53 PE=3 SV=1
Length=112
Score = 36.3 bits (82), Expect = 0.23, Method: Composition-based stats.
Identities = 13/56 (23%), Positives = 23/56 (41%), Gaps = 8/56 (14%)
Query 354 VRTNICPFREDPRAHQNLWQAARLQLLTLQSWLLDAPCSLPAEAALCWRAPGGDPC 409
VR CPF ++ + + QA + + + C + A+ R G +PC
Sbjct 16 VRVQFCPFEKNVESTRTFLQAVS----SEKVRSTNLNCPVIADV----RHDGSEPC 63
>sp|Q8NEZ4|KMT2C_HUMAN Histone-lysine N-methyltransferase 2C OS=Homo
sapiens OX=9606 GN=KMT2C PE=1 SV=3
Length=4911
Score = 38.2 bits (87), Expect = 0.41, Method: Composition-based stats.
Identities = 25/99 (25%), Positives = 34/99 (34%), Gaps = 5/99 (5%)
Query 689 PDFLQGRAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRL 748
P P V + + + P P+ + + QQP+ PR
Sbjct 2130 PYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYS---QQPQTPRPSTQ 2186
Query 749 QERAEQVSRALQPALDSYFHPPGTPAPGRGVGPGAGPGA 787
+ Q D Y HPPGTP PG V P + P A
Sbjct 2187 TDLF-VTPVTNQRHSDPYAHPPGTPRPGISV-PYSQPPA 2223
>sp|Q96EL3|RM53_HUMAN Large ribosomal subunit protein mL53 OS=Homo
sapiens OX=9606 GN=MRPL53 PE=1 SV=1
Length=112
Score = 34.0 bits (76), Expect = 1.2, Method: Composition-based stats.
Identities = 13/56 (23%), Positives = 23/56 (41%), Gaps = 8/56 (14%)
Query 354 VRTNICPFREDPRAHQNLWQAARLQLLTLQSWLLDAPCSLPAEAALCWRAPGGDPC 409
VR CPF ++ + + Q + + + CS+ A+ R G +PC
Sbjct 16 VRVQFCPFEKNVESTRTFLQTVS----SEKVRSTNLNCSVIADV----RHDGSEPC 63
>sp|Q2HJF1|RM53_BOVIN Large ribosomal subunit protein mL53 OS=Bos
taurus OX=9913 GN=MRPL53 PE=1 SV=1
Length=112
Score = 34.0 bits (76), Expect = 1.5, Method: Composition-based stats.
Identities = 14/56 (25%), Positives = 24/56 (43%), Gaps = 8/56 (14%)
Query 354 VRTNICPFREDPRAHQNLWQAARLQLLTLQSWLLDAPCSLPAEAALCWRAPGGDPC 409
VR CPF ++ + + QA + + + CS+ A+ R G +PC
Sbjct 16 VRVQFCPFEKNVESTRTFLQAVS----SEKVRSTNLNCSVIADV----RHDGSEPC 63
>sp|B1XX60|MNMA_LEPCP tRNA-specific 2-thiouridylase MnmA OS=Leptothrix
cholodnii (strain ATCC 51168 / LMG 8142 / SP-6) OX=395495
GN=mnmA PE=3 SV=1
Length=380
Score = 35.9 bits (81), Expect = 1.6, Method: Composition-based stats.
Identities = 22/98 (22%), Positives = 31/98 (32%), Gaps = 2/98 (2%)
Query 618 DLWSRRELSAQG-PVAWFHAQRRQTLQEGGVVVLLFSPGAVALCSEWLQDGVSGPGAHGP 676
DL S + QG W +QR + + + PG L ++ A
Sbjct 276 DLASNTLYAVQGHDHPWLQSQRLS-ADDASWIGTVPQPGQGGLAAKTRYRQADSACAVDA 334
Query 677 HDAFRASLSCVLPDFLQGRAPGSYVGACFDRLLHPDAV 714
DA +LS P PG V + AV
Sbjct 335 LDAAARTLSMSFPAPQWAVTPGQSVVLYEGEVCLGGAV 372
>sp|Q8NBZ0|IN80E_HUMAN INO80 complex subunit E OS=Homo sapiens
OX=9606 GN=INO80E PE=1 SV=1
Length=244
Score = 35.1 bits (79), Expect = 1.9, Method: Composition-based stats.
Identities = 25/82 (30%), Positives = 34/82 (41%), Gaps = 12/82 (15%)
Query 714 VPALFR---TVPVFTLPSQLPDFLGALQQPRAPRSGRLQ-ERAEQVSRALQPALDSYFHP 769
VP+ + + P ALQ P P R + E+ ++ R L+ A+ P
Sbjct 125 VPSPYLSSLASSRYP---PFPSDYLALQLPE-PSPLRPKREKRPRLPRKLKMAVG----P 176
Query 770 PGTPAPGRGVGPGAGPGAGDGT 791
P P G PG G GAG GT
Sbjct 177 PDCPVGGPLTFPGRGSGAGVGT 198
>sp|Q9M156|U72B1_ARATH UDP-glycosyltransferase 72B1 OS=Arabidopsis
thaliana OX=3702 GN=UGT72B1 PE=1 SV=1
Length=480
Score = 35.5 bits (80), Expect = 2.0, Method: Composition-based stats.
Identities = 38/252 (15%), Positives = 69/252 (27%), Gaps = 16/252 (6%)
Query 404 PGGDPCQPLVPPLSWENVTVDKVLEFPLLKGHPNLCVQVNSSEKLQLQECLWADSL---- 459
P P PLV E ++ L P V S C + L
Sbjct 234 PPVYPVGPLVNIGKQEAKQTEESECLKWLDNQPLGSVLYVSFGSGGTLTCEQLNELALGL 293
Query 460 -GPLKDDVLLLETRGPQDNRSLCALEPSG--CTSLPSKASTRAARLGEYLLQDLQSGQCL 516
+ + ++ + N S T LP R + G +++ +
Sbjct 294 ADSEQRFLWVIRSPSGIANSSYFDSHSQTDPLTFLPPGFLERTKKRG-FVIPFWAPQAQV 352
Query 517 QLWDDDLGALWACPMDKYIHKRWALVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVR 576
G L C + + + + L A + +L + + LR D
Sbjct 353 LAHPSTGGFLTHCGWNSTLESVVSGIPLIAWPLYAEQKMNAVLLSEDIRAALRPRAGDDG 412
Query 577 SGAAARGRAAL--LLYSADDSGFERLVGALASALCQLPLRVAVDLWSRRELSAQGPVAWF 634
+ L+ + G + L A C++ A VA
Sbjct 413 LVRREEVARVVKGLMEGEEGKGVRNKMKELKEAACRVLKD------DGTSTKALSLVALK 466
Query 635 HAQRRQTLQEGG 646
++ L++ G
Sbjct 467 WKAHKKELEQNG 478
>sp|Q8BRH4|KMT2C_MOUSE Histone-lysine N-methyltransferase 2C OS=Mus
musculus OX=10090 GN=Kmt2c PE=1 SV=2
Length=4903
Score = 35.9 bits (81), Expect = 2.2, Method: Composition-based stats.
Identities = 25/99 (25%), Positives = 33/99 (33%), Gaps = 5/99 (5%)
Query 689 PDFLQGRAPGSYVGACFDRLLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRL 748
P P + + + P + P P+ + + QQP PR
Sbjct 2123 PYSQPPGTPRPLIDSYSQTSGTARSNPDPYSQPPGTPRPNTIDPYS---QQPPTPRPS-P 2178
Query 749 QERAEQVSRALQPALDSYFHPPGTPAPGRGVGPGAGPGA 787
Q S A Q D Y H G P PG V P + P A
Sbjct 2179 QTDMFVSSVANQRHTDPYTHHLGPPRPGISV-PYSQPPA 2216
Lambda K H a alpha
0.318 0.126 0.363 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0387 0.140 1.90 42.6 43.6
Effective search space used: 89865574330
Database: uniprot_sprot.fasta
Posted date: Oct 6, 2024 4:14 PM
Number of letters in database: 207,235,166
Number of sequences in database: 572,214
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40