PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
573,661 sequences; 207,922,125 total letters
Results from round 1
Query= sp|Q5BJD5|TM41B_HUMAN Transmembrane protein 41B OS=Homo sapiens
OX=9606 GN=TMEM41B PE=1 SV=1
Length=291
Score E
Sequences producing significant alignments: (Bits) Value
sp|Q5BJD5|TM41B_HUMAN Transmembrane protein 41B OS=Homo sapiens O... 595 0.0
sp|Q5RBZ8|TM41B_PONAB Transmembrane protein 41B OS=Pongo abelii O... 579 0.0
sp|Q5FVN2|TM41B_RAT Transmembrane protein 41B OS=Rattus norvegicu... 550 0.0
sp|Q8K1A5|TM41B_MOUSE Transmembrane protein 41B OS=Mus musculus O... 536 0.0
sp|Q5ZIL6|TM41B_CHICK Transmembrane protein 41B OS=Gallus gallus ... 476 9e-171
sp|Q5U4K5|TM41B_XENLA Transmembrane protein 41B OS=Xenopus laevis... 466 1e-166
sp|A4II98|TM41B_XENTR Transmembrane protein 41B OS=Xenopus tropic... 465 2e-166
sp|A1A5V7|TM41B_DANRE Transmembrane protein 41B OS=Danio rerio OX... 416 8e-147
sp|Q9VX39|TM41_DROME Transmembrane protein 41 homolog OS=Drosophi... 281 2e-93
sp|O62126|TM41_CAEEL Transmembrane protein 41 homolog OS=Caenorha... 258 2e-85
sp|Q8MXN7|TM41_DICDI Transmembrane protein 41 homolog OS=Dictyost... 206 2e-63
sp|Q8L586|Y4958_ARATH Uncharacterized membrane protein At4g09580 ... 172 4e-51
sp|Q08D99|TM41A_BOVIN Transmembrane protein 41A OS=Bos taurus OX=... 148 4e-42
sp|Q96HV5|TM41A_HUMAN Transmembrane protein 41A OS=Homo sapiens O... 147 1e-41
sp|Q9D8U2|TM41A_MOUSE Transmembrane protein 41A OS=Mus musculus O... 142 1e-39
sp|Q502G2|T41AA_DANRE Transmembrane protein 41A-A OS=Danio rerio ... 141 4e-39
sp|Q6NV38|T41AB_DANRE Transmembrane protein 41A-B OS=Danio rerio ... 121 2e-31
sp|P76221|YDJZ_ECOLI TVP38/TMEM64 family inner membrane protein Y... 43.1 0.001
sp|Q9HC84|MUC5B_HUMAN Mucin-5B OS=Homo sapiens OX=9606 GN=MUC5B P... 34.3 1.8
sp|A7TF84|ATG26_VANPO Sterol 3-beta-glucosyltransferase OS=Vander... 33.5 2.6
sp|Q5UPF1|YL072_MIMIV Putative ankyrin repeat protein L72 OS=Acan... 32.7 3.5
sp|P96665|YDEH_BACSU Uncharacterized membrane protein YdeH OS=Bac... 31.2 5.4
sp|P57318|FTSL_BUCAI Cell division protein FtsL OS=Buchnera aphid... 29.6 6.0
sp|P55399|TRBE2_SINFN Probable conjugal transfer protein TrbE par... 32.0 7.3
sp|C4V847|SYNC_VAIC1 Probable asparagine--tRNA ligase, cytoplasmi... 31.6 9.6
>sp|Q5BJD5|TM41B_HUMAN Transmembrane protein 41B OS=Homo sapiens
OX=9606 GN=TMEM41B PE=1 SV=1
Length=291
Score = 595 bits (1534), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 291/291 (100%), Positives = 291/291 (100%), Gaps = 0/291 (0%)
Query 1 MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI 60
MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI
Sbjct 1 MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI 60
Query 61 FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT
Sbjct 61 FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
Query 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT
Sbjct 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
Query 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP
Sbjct 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
Query 241 SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE
Sbjct 241 SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
>sp|Q5RBZ8|TM41B_PONAB Transmembrane protein 41B OS=Pongo abelii
OX=9601 GN=TMEM41B PE=2 SV=1
Length=291
Score = 579 bits (1492), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 284/291 (98%), Positives = 287/291 (99%), Gaps = 0/291 (0%)
Query 1 MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI 60
MAKGRVAERSQ+GA HTTPVGDGAAGTRG AAPGSRD+QKEKSW EAGSARMSLLILVSI
Sbjct 1 MAKGRVAERSQMGADHTTPVGDGAAGTRGPAAPGSRDYQKEKSWAEAGSARMSLLILVSI 60
Query 61 FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT
Sbjct 61 FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
Query 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT
Sbjct 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
Query 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP
Sbjct 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
Query 241 SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
SFVAIKAGTTL+Q TTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE
Sbjct 241 SFVAIKAGTTLHQPTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
>sp|Q5FVN2|TM41B_RAT Transmembrane protein 41B OS=Rattus norvegicus
OX=10116 GN=Tmem41b PE=2 SV=1
Length=291
Score = 550 bits (1418), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 271/291 (93%), Positives = 277/291 (95%), Gaps = 0/291 (0%)
Query 1 MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI 60
MAKGRVAERSQ H+TP GD A GT+G AAPG++DH KEK VEAGSAR SLLILVSI
Sbjct 1 MAKGRVAERSQTEMLHSTPAGDRAVGTQGSAAPGNKDHLKEKPCVEAGSARTSLLILVSI 60
Query 61 FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
F AAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT
Sbjct 61 FSCAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
Query 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT
Sbjct 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
Query 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP
Sbjct 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
Query 241 SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
SFVAIKAGTTLYQLTTAGEAVSWNS+FILMILA+LSILPAIFQKKLKQKFE
Sbjct 241 SFVAIKAGTTLYQLTTAGEAVSWNSVFILMILALLSILPAIFQKKLKQKFE 291
>sp|Q8K1A5|TM41B_MOUSE Transmembrane protein 41B OS=Mus musculus
OX=10090 GN=Tmem41b PE=1 SV=1
Length=291
Score = 536 bits (1380), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 263/291 (90%), Positives = 273/291 (94%), Gaps = 0/291 (0%)
Query 1 MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI 60
MAKGRVA+RS H+TP GD A T+G AAPGS+DH EK EAGSAR SLLILVSI
Sbjct 1 MAKGRVADRSPTEMLHSTPAGDRAVRTQGSAAPGSKDHLNEKPCAEAGSARTSLLILVSI 60
Query 61 FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
F AAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT
Sbjct 61 FSCAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
Query 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT
Sbjct 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
Query 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP
Sbjct 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
Query 241 SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
SFVAIKAGTTL+QLTTAGEAVSW+S+FILM+LA+LSILPAIFQK+LKQKFE
Sbjct 241 SFVAIKAGTTLHQLTTAGEAVSWSSVFILMVLALLSILPAIFQKQLKQKFE 291
>sp|Q5ZIL6|TM41B_CHICK Transmembrane protein 41B OS=Gallus gallus
OX=9031 GN=TMEM41B PE=2 SV=1
Length=269
Score = 476 bits (1225), Expect = 9e-171, Method: Compositional matrix adjust.
Identities = 236/264 (89%), Positives = 247/264 (94%), Gaps = 3/264 (1%)
Query 31 AAPGSRDHQK---EKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMK 87
AA S HQ+ K+ E GSAR SLLILVSIF AAF+MFLVYKNFPQLSEEE +K
Sbjct 6 AAAESARHQRLLEGKAQAEGGSARTSLLILVSIFTIAAFLMFLVYKNFPQLSEEEGKCIK 65
Query 88 VPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPL 147
+PRDMDDAKALGKVLSKYKDTFYVQVLVAYFATY+FLQTFAIPGSIFLSILSGFLYPFPL
Sbjct 66 IPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYVFLQTFAIPGSIFLSILSGFLYPFPL 125
Query 148 ALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRIT 207
ALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWS+QVERHREHLINYIIFLRIT
Sbjct 126 ALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSEQVERHREHLINYIIFLRIT 185
Query 208 PFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIF 267
PFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNS+F
Sbjct 186 PFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSLF 245
Query 268 ILMILAVLSILPAIFQKKLKQKFE 291
+LMILA+LSILPA+FQKKLKQKFE
Sbjct 246 VLMILAILSILPALFQKKLKQKFE 269
>sp|Q5U4K5|TM41B_XENLA Transmembrane protein 41B OS=Xenopus laevis
OX=8355 GN=tmem41b PE=2 SV=1
Length=278
Score = 466 bits (1198), Expect = 1e-166, Method: Compositional matrix adjust.
Identities = 235/287 (82%), Positives = 248/287 (86%), Gaps = 10/287 (3%)
Query 5 RVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSA 64
+V ERS G H G A + H E GSARMSLLILVSIFL A
Sbjct 2 QVHERSHTGGH----TFQCNHGNEKKAPAAGKVHS------EGGSARMSLLILVSIFLCA 51
Query 65 AFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFL 124
A VMFLVYK FPQLSEEE +KVPRDMDDAKALGKVLSKYKDTFYV+VLVAYF TYIFL
Sbjct 52 ASVMFLVYKYFPQLSEEELEKIKVPRDMDDAKALGKVLSKYKDTFYVEVLVAYFTTYIFL 111
Query 125 QTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAV 184
QTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCY+LSYLVGRPVVYKYL++KA+
Sbjct 112 QTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYLLSYLVGRPVVYKYLSDKAI 171
Query 185 KWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVA 244
KWSQQVERHR+HLINYIIFLRITPFLPNWFINITSPVINVPLKVFF+GTF+GVAPPSFVA
Sbjct 172 KWSQQVERHRDHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFLGTFIGVAPPSFVA 231
Query 245 IKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
IKAGTTLYQLTTAGEAVSWNS+ ILM+LAVLSILPAIFQKKLKQKFE
Sbjct 232 IKAGTTLYQLTTAGEAVSWNSVIILMVLAVLSILPAIFQKKLKQKFE 278
>sp|A4II98|TM41B_XENTR Transmembrane protein 41B OS=Xenopus tropicalis
OX=8364 GN=tmem41b PE=2 SV=1
Length=278
Score = 465 bits (1197), Expect = 2e-166, Method: Compositional matrix adjust.
Identities = 235/287 (82%), Positives = 252/287 (88%), Gaps = 10/287 (3%)
Query 5 RVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSA 64
+V ERS G H T G+ AP + K E GSARMSLLILVSIFL A
Sbjct 2 QVHERSHTGGH-TCQCNHGSEKK----APAT-----GKVHSEGGSARMSLLILVSIFLCA 51
Query 65 AFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFL 124
A +MFLVYK+FPQLSEEER +KVPRDMDDAKALGKVLSKYKDTFYV+VLVAYF TYIFL
Sbjct 52 ASIMFLVYKHFPQLSEEEREKIKVPRDMDDAKALGKVLSKYKDTFYVEVLVAYFTTYIFL 111
Query 125 QTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAV 184
QTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASF Y+LSYLVGRPVVYKYL++KA+
Sbjct 112 QTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFSYLLSYLVGRPVVYKYLSDKAI 171
Query 185 KWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVA 244
KWSQQVERHR+HLINYIIFLRITPFLPNWFINITSPVINVPLKVFF+GTF+GVAPPSFVA
Sbjct 172 KWSQQVERHRDHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFLGTFIGVAPPSFVA 231
Query 245 IKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
IKAGTTLYQLTTAGEAVSWNS+ ILM+LAVLSILPAIFQKKLK+KFE
Sbjct 232 IKAGTTLYQLTTAGEAVSWNSVIILMVLAVLSILPAIFQKKLKKKFE 278
>sp|A1A5V7|TM41B_DANRE Transmembrane protein 41B OS=Danio rerio
OX=7955 GN=tmem41b PE=2 SV=1
Length=282
Score = 416 bits (1068), Expect = 8e-147, Method: Compositional matrix adjust.
Identities = 211/290 (73%), Positives = 239/290 (82%), Gaps = 13/290 (4%)
Query 2 AKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIF 61
A R E S L P + +G +PG SARMS+L+LV IF
Sbjct 6 AGNRETESSPLVEQEPRPSKETPV-PKGAQSPG------------GASARMSILLLVVIF 52
Query 62 LSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATY 121
+A VM+LV++NFPQLSE+ER +K+P+DM+DAKALG VLSKYKDT+Y QVL+AYFATY
Sbjct 53 ACSACVMYLVFRNFPQLSEDEREKIKIPKDMEDAKALGTVLSKYKDTYYTQVLLAYFATY 112
Query 122 IFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTE 181
IFLQTFAIPGSIFLSILSG+LYPFPLALFLVCLCSGLGASFCYMLSYLVGRP+VYKYLTE
Sbjct 113 IFLQTFAIPGSIFLSILSGYLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPMVYKYLTE 172
Query 182 KAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPS 241
+A KWSQQV++HREHLINYIIFLRITPFLPNWFINITSPVINVPL VFF+GTFLGVAPPS
Sbjct 173 RAQKWSQQVDKHREHLINYIIFLRITPFLPNWFINITSPVINVPLGVFFLGTFLGVAPPS 232
Query 242 FVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
FVAI AGTTLY+LTTAGEAVSWNS+ +L +LAV+SILP FQKKL+QK E
Sbjct 233 FVAINAGTTLYKLTTAGEAVSWNSLLVLGVLAVVSILPVCFQKKLQQKLE 282
>sp|Q9VX39|TM41_DROME Transmembrane protein 41 homolog OS=Drosophila
melanogaster OX=7227 GN=stas PE=2 SV=2
Length=320
Score = 281 bits (720), Expect = 2e-93, Method: Compositional matrix adjust.
Identities = 130/246 (53%), Positives = 177/246 (72%), Gaps = 0/246 (0%)
Query 46 EAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKY 105
E + + SL+I+ IF+++ M VY FP+L+ E+ ++K+PRD+ DAK L KVL +Y
Sbjct 74 EKKATKKSLVIVAGIFVASLVTMCYVYAIFPELNASEKQHLKIPRDIQDAKMLAKVLDRY 133
Query 106 KDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYM 165
KD +Y +V+ Y+FLQTFAIPGS+FLSIL GFLY FP+ALFL+C CS LGA+ CY
Sbjct 134 KDMYYFEVMFGVVVAYVFLQTFAIPGSLFLSILLGFLYKFPIALFLICFCSALGATLCYT 193
Query 166 LSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVP 225
LS LVGR ++ + +K +WS+ VE +R+ L NY++FLR+TP LPNWFIN+ SPVI VP
Sbjct 194 LSNLVGRRLIRHFWPKKTSEWSKHVEEYRDSLFNYMLFLRMTPILPNWFINLASPVIGVP 253
Query 226 LKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKK 285
L +F +GTF GVAPPS +AI+AG TL ++T++ EA SW S+ ILM A S+LP + + K
Sbjct 254 LHIFALGTFCGVAPPSVIAIQAGKTLQKMTSSSEAFSWTSMGILMACACASLLPGLLKNK 313
Query 286 LKQKFE 291
K K E
Sbjct 314 FKHKKE 319
>sp|O62126|TM41_CAEEL Transmembrane protein 41 homolog OS=Caenorhabditis
elegans OX=6239 GN=tag-175 PE=3 SV=1
Length=246
Score = 258 bits (660), Expect = 2e-85, Method: Compositional matrix adjust.
Identities = 123/230 (53%), Positives = 166/230 (72%), Gaps = 0/230 (0%)
Query 60 IFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFA 119
IF + A +F VY NFP++S +E+V++K PR+++DAK LG+VLSKYK+ Y VL
Sbjct 17 IFATFAVSIFAVYSNFPEVSADEKVHLKYPRNLEDAKQLGRVLSKYKENNYSVVLCGVIV 76
Query 120 TYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYL 179
Y+FLQ+FAIPGSIFL+ILSG+L+PF +A+ LVC CS GA+ CY +S L GR V +
Sbjct 77 VYVFLQSFAIPGSIFLTILSGYLFPFYVAIVLVCSCSATGAAICYTISKLFGRSFVLQKF 136
Query 180 TEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAP 239
E+ KW + +HR+ +NY+IFLR+TP +PNW INI SPV++VPL FF GTFLGVAP
Sbjct 137 PERIAKWQDDLSKHRDDFLNYMIFLRVTPIVPNWLINIASPVLDVPLAPFFWGTFLGVAP 196
Query 240 PSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQK 289
PSF+ I+AG+TL QL+ A SW+SI +L A+LS+ P + +KKLK
Sbjct 197 PSFLYIQAGSTLEQLSHTSVAWSWSSIVLLTGSAILSLAPILLKKKLKSD 246
>sp|Q8MXN7|TM41_DICDI Transmembrane protein 41 homolog OS=Dictyostelium
discoideum OX=44689 GN=DDB_G0275543 PE=3 SV=2
Length=334
Score = 206 bits (523), Expect = 2e-63, Method: Compositional matrix adjust.
Identities = 102/238 (43%), Positives = 154/238 (65%), Gaps = 0/238 (0%)
Query 50 ARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTF 109
A + L +LV +F + V+ ++ NFP LS + + +++P++ D K L +LS+Y D
Sbjct 95 APLPLWLLVIVFGVSISVIVFLFLNFPSLSPQHKQLIRLPKNFKDVKLLSDILSQYTDDN 154
Query 110 YVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYL 169
Y V+ + Y FLQ F+IPGS+FLS LSG L+ + LVC + LGA+F Y++SY
Sbjct 155 YFIVITTFGVIYTFLQAFSIPGSVFLSFLSGGLFGLKVGFPLVCFVATLGATFSYLISYY 214
Query 170 VGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVF 229
+GR +V K +K +S + + R++L+NYI+FLRITPFLPNWFIN+ SP+++VP+ F
Sbjct 215 IGRNLVRKLFPDKLKLFSDSLSQKRDNLLNYIVFLRITPFLPNWFINLASPLLDVPIHTF 274
Query 230 FIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLK 287
IGTF+G+ P +F+A+KAG + + + SI + LA+LSILP + QKKLK
Sbjct 275 AIGTFIGIMPATFLAVKAGIQIQNIQNPSDIFDLKSILTMAALALLSILPTLIQKKLK 332
>sp|Q8L586|Y4958_ARATH Uncharacterized membrane protein At4g09580
OS=Arabidopsis thaliana OX=3702 GN=At4g09580 PE=1 SV=1
Length=287
Score = 172 bits (436), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 94/275 (34%), Positives = 155/275 (56%), Gaps = 6/275 (2%)
Query 11 QLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSAAFVMFL 70
QL +P AA +GL S ++ KS +R + ++FL +F
Sbjct 15 QLVKDEESPAASSAA--KGLLNDDSPTGKRTKS-ERFPLSRWEFAVFFTVFLVFTTGLFC 71
Query 71 VYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIP 130
+Y P E +KVPR + D + L + L Y + + ++ Y +TYIF+QTF IP
Sbjct 72 IYLTMPA---AEYGKLKVPRTISDLRLLKENLGSYASEYQARFILGYCSTYIFMQTFMIP 128
Query 131 GSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQV 190
G+IF+S+L+G L+ LV L + GA C+ LS LVGRP+V EK + ++
Sbjct 129 GTIFMSLLAGALFGVVRGFVLVVLNATAGACSCFFLSKLVGRPLVNWLWPEKLRFFQAEI 188
Query 191 ERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTT 250
+ R+ L+NY++FLRITP LPN FIN++SP++++P VFF+ T +G+ P S++ ++AG
Sbjct 189 AKRRDRLLNYMLFLRITPTLPNLFINLSSPIVDIPFHVFFLATLVGLMPASYITVRAGLA 248
Query 251 LYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKK 285
L L + + + ++ +L ++ +SI PA+ ++K
Sbjct 249 LGDLRSVKDLYDFKTLSVLFLIGSISIFPALLKRK 283
>sp|Q08D99|TM41A_BOVIN Transmembrane protein 41A OS=Bos taurus
OX=9913 GN=TMEM41A PE=2 SV=1
Length=264
Score = 148 bits (374), Expect = 4e-42, Method: Compositional matrix adjust.
Identities = 81/243 (33%), Positives = 147/243 (60%), Gaps = 6/243 (2%)
Query 53 SLLILVSIFLSAAFVMFLVYKNFPQ----LSEEERVNMKV--PRDMDDAKALGKVLSKYK 106
SLL L+ +F + F ++L+ P+ +S EE + + P D+ + + L +VL +Y+
Sbjct 3 SLLGLLLVFAGSTFALYLLSTRLPRASTLVSAEESGDRSLWFPSDLAELRELSEVLREYR 62
Query 107 DTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYML 166
V V + + + Y++ Q+FAIPGS FL++L+G L+ L L L C+ + +GA+ CY+L
Sbjct 63 KEHQVYVFLLFCSAYLYKQSFAIPGSSFLNVLAGALFGPWLGLLLCCVLTSVGATGCYLL 122
Query 167 SYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPL 226
S + G+ +V Y +K ++VE +R L +++FLR+ P PNWF+N+++P++N+P+
Sbjct 123 SSVFGKQLVVFYFPDKVALLQKKVEENRNGLFFFLLFLRLFPMTPNWFLNLSAPILNIPI 182
Query 227 KVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKL 286
FF +G+ P +F+ ++ G+ L LT+ SW + F L+ +A+++++P KK
Sbjct 183 VQFFFSVLIGLIPYNFICVQTGSILSTLTSLDALFSWETAFKLLAIALVALVPGTLIKKF 242
Query 287 KQK 289
QK
Sbjct 243 SQK 245
>sp|Q96HV5|TM41A_HUMAN Transmembrane protein 41A OS=Homo sapiens
OX=9606 GN=TMEM41A PE=1 SV=1
Length=264
Score = 147 bits (371), Expect = 1e-41, Method: Compositional matrix adjust.
Identities = 78/242 (32%), Positives = 141/242 (58%), Gaps = 6/242 (2%)
Query 54 LLILVSIFLSAAFVMFLVYKNFPQ---LSEEERVNMK---VPRDMDDAKALGKVLSKYKD 107
LL L+ +F F ++L+ P+ L E + P D+ + + L +VL +Y+
Sbjct 4 LLGLLLVFAGCTFALYLLSTRLPRGRRLGSTEEAGGRSLWFPSDLAELRELSEVLREYRK 63
Query 108 TFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLS 167
V + + Y++ Q FAIPGS FL++L+G L+ L L L C+ + +GA+ CY+LS
Sbjct 64 EHQAYVFLLFCGAYLYKQGFAIPGSSFLNVLAGALFGPWLGLLLCCVLTSVGATCCYLLS 123
Query 168 YLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLK 227
+ G+ +V Y +K ++VE +R L +++FLR+ P PNWF+N+++P++N+P+
Sbjct 124 SIFGKQLVVSYFPDKVALLQRKVEENRNSLFFFLLFLRLFPMTPNWFLNLSAPILNIPIV 183
Query 228 VFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLK 287
FF +G+ P +F+ ++ G+ L LT+ SW+++F L+ +A+++++P KK
Sbjct 184 QFFFSVLIGLIPYNFICVQTGSILSTLTSLDALFSWDTVFKLLAIAMVALIPGTLIKKFS 243
Query 288 QK 289
QK
Sbjct 244 QK 245
>sp|Q9D8U2|TM41A_MOUSE Transmembrane protein 41A OS=Mus musculus
OX=10090 GN=Tmem41a PE=2 SV=1
Length=264
Score = 142 bits (357), Expect = 1e-39, Method: Compositional matrix adjust.
Identities = 71/210 (34%), Positives = 128/210 (61%), Gaps = 0/210 (0%)
Query 80 EEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILS 139
E E ++ P D+ + + L +VL +Y+ V + + + Y++ Q FAIPGS FL++L+
Sbjct 36 EPEGRSLWFPSDLAELRELSEVLREYRKEHQAYVFLLFCSAYLYKQGFAIPGSSFLNVLA 95
Query 140 GFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLIN 199
G L+ L L L C+ + +GA+ CY+LS L G+ +V Y +K ++VE +R L
Sbjct 96 GALFGPWLGLLLCCVLTSVGATGCYLLSSLFGKQLVISYFPDKVALLQKKVEENRNSLFF 155
Query 200 YIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGE 259
+++FLR+ P PNWF+N+++P++N+P+ FF +G+ P +F+ ++ G+ L LT+
Sbjct 156 FLLFLRLFPMTPNWFLNLSAPILNIPIVQFFFSVLIGLIPYNFICVQTGSILSTLTSLDA 215
Query 260 AVSWNSIFILMILAVLSILPAIFQKKLKQK 289
SW ++ L+ +A+++++P KK QK
Sbjct 216 LFSWETVLKLLAIALVALVPGTLIKKFSQK 245
>sp|Q502G2|T41AA_DANRE Transmembrane protein 41A-A OS=Danio rerio
OX=7955 GN=tmem41aa PE=2 SV=1
Length=281
Score = 141 bits (355), Expect = 4e-39, Method: Compositional matrix adjust.
Identities = 71/210 (34%), Positives = 127/210 (60%), Gaps = 0/210 (0%)
Query 76 PQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFL 135
P E +K P D+D+ K + ++L YK VL+ + + Y++ Q FAIPGS FL
Sbjct 49 PSEMETASSRLKFPSDLDELKEMAELLQFYKTEHTGYVLLLFCSAYLYKQAFAIPGSSFL 108
Query 136 SILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHRE 195
+IL+G L+ L L C+ + +GA+ C++LS G+ + K +K ++VE +R
Sbjct 109 NILAGALFGTWFGLLLTCVLTTVGATLCFLLSQAFGKHHIVKLFPDKVAMLQKKVEENRS 168
Query 196 HLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLT 255
L +++FLR P PNWF+N+TSP++N+P+ +FF+ F+G+ P +F+ ++ G+ L Q++
Sbjct 169 SLFFFLLFLRFFPMSPNWFLNMTSPILNIPVTLFFMAVFIGLMPYNFICVQTGSMLSQIS 228
Query 256 TAGEAVSWNSIFILMILAVLSILPAIFQKK 285
+ + SW+ + L++ A +++LP +K
Sbjct 229 SLDDLFSWSVVLKLLLTACVALLPGALIRK 258
>sp|Q6NV38|T41AB_DANRE Transmembrane protein 41A-B OS=Danio rerio
OX=7955 GN=tmem41ab PE=2 SV=1
Length=278
Score = 121 bits (303), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 72/239 (30%), Positives = 135/239 (56%), Gaps = 4/239 (2%)
Query 55 LILVSIFLSAAFVMFLVYKNFPQLS----EEERVNMKVPRDMDDAKALGKVLSKYKDTFY 110
L L+S FL V+ P+ + EE+ + +K P D+++ + L ++L YK
Sbjct 18 LYLLSAFLPPGPRAIRVHDTGPEHTDDEPEEKVLRLKFPSDLEELRELAELLKFYKTEHT 77
Query 111 VQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLV 170
V + + + Y++ Q+FAIPGS FL++LSG L+ L + C + +G++ CY+LS
Sbjct 78 GYVFILFCSAYLYKQSFAIPGSSFLNMLSGALFGPLHGLIIACTLTTVGSTNCYLLSRTF 137
Query 171 GRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFF 230
G+ + + EK + VE +R L +++FLR P PNWF+N+TSP++N+P+ +FF
Sbjct 138 GKRHIVRLFPEKVAMLQRMVEENRSSLFFFLLFLRFFPMTPNWFLNVTSPILNIPIPIFF 197
Query 231 IGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQK 289
+G+ P +F+ + G L ++ + + SW ++ L+++A +++LP ++ +
Sbjct 198 FSILIGLIPYNFICVHTGAVLSEINSLDDIFSWFTLLQLLLIACVALLPGALIRRYSKD 256
>sp|P76221|YDJZ_ECOLI TVP38/TMEM64 family inner membrane protein
YdjZ OS=Escherichia coli (strain K12) OX=83333 GN=ydjZ PE=1
SV=1
Length=235
Score = 43.1 bits (100), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 69/246 (28%), Positives = 106/246 (43%), Gaps = 40/246 (16%)
Query 39 QKEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPR-DMDDAKA 97
Q K W R++L+IL+ F M L + P + E +N V D +
Sbjct 5 QSRKIWYY----RITLIILL-------FAMLLAWALLPGV--HEFINRSVAAFAAVDQQG 51
Query 98 LGKVLSKYKD-----TFYVQVLVAYFATY-IFLQTFAIPGSIFLSILSGFLYPFPLALFL 151
+ + + Y +F + +L A A FL TFA S+F + G L
Sbjct 52 IERFIQSYGALAAVVSFLLMILQAIAAPLPAFLITFA-NASLFGAFWGGLLS-------- 102
Query 152 VCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQ--VERHREHLINYIIFLRITPF 209
S GA+ C+ ++ ++GR VV K LT K V S R+ +H I + R+ PF
Sbjct 103 -WTSSMAGAALCFFIARVMGREVVEK-LTGKTVLDSMDGFFTRYGKHTI---LVCRLLPF 157
Query 210 LPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFIL 269
+P I+ + + ++ + FFI T LG P + V AG+ L T G +FIL
Sbjct 158 VPFDPISYAAGLTSIRFRSFFIATGLGQLPATIVYSWAGSML----TGGTFWFVTGLFIL 213
Query 270 MILAVL 275
L V+
Sbjct 214 FALTVV 219
>sp|Q9HC84|MUC5B_HUMAN Mucin-5B OS=Homo sapiens OX=9606 GN=MUC5B
PE=1 SV=3
Length=5762
Score = 34.3 bits (77), Expect = 1.8, Method: Composition-based stats.
Identities = 17/45 (38%), Positives = 20/45 (44%), Gaps = 0/45 (0%)
Query 6 VAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSA 50
V S LG HT PV + A T G + P S H +W A S
Sbjct 3433 VTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSG 3477
Score = 33.9 bits (76), Expect = 2.4, Method: Composition-based stats.
Identities = 17/45 (38%), Positives = 20/45 (44%), Gaps = 0/45 (0%)
Query 6 VAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSA 50
V S LG HT PV + A T G + P S H +W A S
Sbjct 2176 VTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSG 2220
>sp|A7TF84|ATG26_VANPO Sterol 3-beta-glucosyltransferase OS=Vanderwaltozyma
polyspora (strain ATCC 22028 / DSM 70294 / BCRC
21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) OX=436907
GN=ATG26 PE=3 SV=1
Length=1217
Score = 33.5 bits (75), Expect = 2.6, Method: Composition-based stats.
Identities = 26/94 (28%), Positives = 46/94 (49%), Gaps = 2/94 (2%)
Query 66 FVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQ 125
F +F + K ++S + VN + RD+D K L + + KY + L+ ++ ++ LQ
Sbjct 161 FNIFKIPKKDEKISNDMEVNNTLSRDLDYKKDLFEFVRKYFGISEEETLIGHYTGWL-LQ 219
Query 126 TFAIPGSIFLSILS-GFLYPFPLALFLVCLCSGL 158
I G++F++ S +L P V LC L
Sbjct 220 EVLIQGNLFITNSSLVYLAHLPKLTDAVVLCGKL 253
>sp|Q5UPF1|YL072_MIMIV Putative ankyrin repeat protein L72 OS=Acanthamoeba
polyphaga mimivirus OX=212035 GN=MIMI_L72 PE=4
SV=1
Length=384
Score = 32.7 bits (73), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 42/176 (24%), Positives = 73/176 (41%), Gaps = 20/176 (11%)
Query 92 MDDAKALGKVLS------KYKDTFY-VQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYP 144
MDD K++S +K+ + V +L+A +I + + I LS+ LY
Sbjct 148 MDDLTRSNKLISTQEIFTDFKNNDHNVCILIAIVYKHIDVVKYFISIGEILSVKDDSLY- 206
Query 145 FPLALFLVCLCS-----------GLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERH 193
F LA CL ++C M+S + GR + +Y+ + V + V++
Sbjct 207 FKLACDTGCLNIIKYLLEIGFDIESNNNYCLMISTINGRNDIVEYIKSRGVNPNNHVKKC 266
Query 194 REHLINYIIFLRITP-FLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAG 248
+ + N+ L+ + FL FI T N+ ++ I G + IKAG
Sbjct 267 IQIITNHNDDLKSSDIFLMTKFIKTTGVNSNILYQLLLIACEYGYYSMTMYLIKAG 322
>sp|P96665|YDEH_BACSU Uncharacterized membrane protein YdeH OS=Bacillus
subtilis (strain 168) OX=224308 GN=ydeH PE=4 SV=1
Length=148
Score = 31.2 bits (69), Expect = 5.4, Method: Compositional matrix adjust.
Identities = 22/69 (32%), Positives = 37/69 (54%), Gaps = 1/69 (1%)
Query 198 INYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTA 257
I ++FL I P + ++F N+ +I+ + F + TFLG+ P F+ I G ++ A
Sbjct 68 IGIVVFLLIPPLVMSFFGNLVVRIISGVYQCFIVFTFLGLIPIGFL-IPNGFLTILVSIA 126
Query 258 GEAVSWNSI 266
G VS S+
Sbjct 127 GTLVSIASV 135
>sp|P57318|FTSL_BUCAI Cell division protein FtsL OS=Buchnera aphidicola
subsp. Acyrthosiphon pisum (strain APS) OX=107806
GN=ftsL PE=3 SV=1
Length=67
Score = 29.6 bits (65), Expect = 6.0, Method: Composition-based stats.
Identities = 15/43 (35%), Positives = 25/43 (58%), Gaps = 0/43 (0%)
Query 50 ARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDM 92
++ L +L++I LSA+ V+ VY ++EEE V K + M
Sbjct 20 GKIHLTLLIAIILSASLVIITVYNTRLLITEEEDVIQKKKKKM 62
>sp|P55399|TRBE2_SINFN Probable conjugal transfer protein TrbE
part 2 OS=Sinorhizobium fredii (strain NBRC 101917 / NGR234)
OX=394 GN=trbEB PE=3 SV=1
Length=662
Score = 32.0 bits (71), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 19/69 (28%), Positives = 32/69 (46%), Gaps = 13/69 (19%)
Query 212 NWFINITSPVIN-------VPLKVFFIGTFLGVAP------PSFVAIKAGTTLYQLTTAG 258
NW+ NI P+IN +PL + G+ + P PS + + +G+T ++L
Sbjct 238 NWYCNIREPLINTSNLADLIPLNSVWSGSPVAPCPFYPPNSPSLMQVASGSTPFRLNLHV 297
Query 259 EAVSWNSIF 267
+ V IF
Sbjct 298 DDVGHTLIF 306
>sp|C4V847|SYNC_VAIC1 Probable asparagine--tRNA ligase, cytoplasmic
OS=Vairimorpha ceranae (strain BRL01) OX=578460 GN=NCER_100652
PE=3 SV=1
Length=447
Score = 31.6 bits (70), Expect = 9.6, Method: Compositional matrix adjust.
Identities = 12/44 (27%), Positives = 27/44 (61%), Gaps = 2/44 (5%)
Query 213 WFINITSPVINVPLKVFFIGTFLGVAPPSFV--AIKAGTTLYQL 254
+F+ S ++ + +F+ G F+ + PP+ V ++ G+TL++L
Sbjct 139 FFLKARSSLLKIIRDIFYEGNFIEITPPTIVQTQVEGGSTLFKL 182
Lambda K H a alpha
0.327 0.140 0.422 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 24499859112
Results from round 2
Query= sp|Q5BJD5|TM41B_HUMAN Transmembrane protein 41B OS=Homo sapiens
OX=9606 GN=TMEM41B PE=1 SV=1
Length=291
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|Q5BJD5|TM41B_HUMAN Transmembrane protein 41B OS=Homo sapiens O... 414 4e-146
sp|Q5RBZ8|TM41B_PONAB Transmembrane protein 41B OS=Pongo abelii O... 412 2e-145
sp|Q5FVN2|TM41B_RAT Transmembrane protein 41B OS=Rattus norvegicu... 404 6e-142
sp|Q8K1A5|TM41B_MOUSE Transmembrane protein 41B OS=Mus musculus O... 397 3e-139
sp|Q5U4K5|TM41B_XENLA Transmembrane protein 41B OS=Xenopus laevis... 368 5e-128
sp|A4II98|TM41B_XENTR Transmembrane protein 41B OS=Xenopus tropic... 366 4e-127
sp|Q5ZIL6|TM41B_CHICK Transmembrane protein 41B OS=Gallus gallus ... 350 4e-121
sp|A1A5V7|TM41B_DANRE Transmembrane protein 41B OS=Danio rerio OX... 347 1e-119
sp|Q9VX39|TM41_DROME Transmembrane protein 41 homolog OS=Drosophi... 317 3e-107
sp|O62126|TM41_CAEEL Transmembrane protein 41 homolog OS=Caenorha... 291 5e-98
sp|Q8L586|Y4958_ARATH Uncharacterized membrane protein At4g09580 ... 292 7e-98
sp|Q96HV5|TM41A_HUMAN Transmembrane protein 41A OS=Homo sapiens O... 274 3e-91
sp|Q08D99|TM41A_BOVIN Transmembrane protein 41A OS=Bos taurus OX=... 269 3e-89
sp|Q9D8U2|TM41A_MOUSE Transmembrane protein 41A OS=Mus musculus O... 264 2e-87
sp|Q8MXN7|TM41_DICDI Transmembrane protein 41 homolog OS=Dictyost... 266 5e-87
sp|Q502G2|T41AA_DANRE Transmembrane protein 41A-A OS=Danio rerio ... 254 4e-83
sp|Q6NV38|T41AB_DANRE Transmembrane protein 41A-B OS=Danio rerio ... 245 1e-79
sp|P76221|YDJZ_ECOLI TVP38/TMEM64 family inner membrane protein Y... 153 3e-44
Sequences not found previously or not previously below threshold:
sp|Q55909|Y305_SYNY3 TVP38/TMEM64 family membrane protein slr0305... 66.2 1e-11
sp|P67118|Y1528_MYCBO TVP38/TMEM64 family membrane protein Mb1528... 55.8 7e-08
sp|P9WFS3|Y1491_MYCTU TVP38/TMEM64 family membrane protein Rv1491... 55.8 7e-08
sp|P9WFS2|Y1491_MYCTO TVP38/TMEM64 family membrane protein MT1538... 55.8 7e-08
sp|P76219|YDJX_ECOLI TVP38/TMEM64 family membrane protein YdjX OS... 54.3 2e-07
sp|P06568|YTXB_BACSU TVP38/TMEM64 family membrane protein YtxB OS... 53.1 4e-07
sp|P54449|YQED_BACSU Uncharacterized protein YqeD OS=Bacillus sub... 52.8 5e-07
sp|Q6BQJ1|TVP38_DEBHA Golgi apparatus membrane protein TVP38 OS=D... 52.0 2e-06
sp|Q3U145|TMM64_MOUSE Transmembrane protein 64 OS=Mus musculus OX... 50.5 8e-06
sp|Q6YI46|TMM64_HUMAN Transmembrane protein 64 OS=Homo sapiens OX... 45.1 4e-04
sp|O07559|YHJE_BACSU Uncharacterized membrane protein YhjE OS=Bac... 42.4 0.002
sp|Q2UUJ9|TVP38_ASPOR Golgi apparatus membrane protein tvp38 OS=A... 41.2 0.008
sp|P67116|Y641_MYCBO TVP38/TMEM64 family membrane protein Mb0641c... 40.8 0.008
sp|P9WFS5|Y625_MYCTU TVP38/TMEM64 family membrane protein Rv0625c... 40.8 0.008
sp|P9WFS4|Y625_MYCTO TVP38/TMEM64 family membrane protein MT0653 ... 40.8 0.008
sp|A5DH87|TVP38_PICGU Golgi apparatus membrane protein TVP38 OS=M... 40.8 0.010
sp|Q57819|Y374_METJA Uncharacterized protein MJ0374 OS=Methanocal... 40.8 0.010
sp|O31823|UPTA_BACSU Undecaprenyl phosphate transporter A OS=Baci... 38.9 0.021
sp|A0A0H3H138|DEDA_KLEPH DedA family protein OS=Klebsiella pneumo... 38.5 0.032
sp|A1CW44|TVP38_NEOFI Golgi apparatus membrane protein tvp38 OS=N... 38.9 0.043
sp|Q4WQJ2|TVP38_ASPFU Golgi apparatus membrane protein tvp38 OS=A... 38.9 0.046
sp|B0Y4Q5|TVP38_ASPFC Golgi apparatus membrane protein tvp38 OS=A... 38.9 0.047
sp|A1CIM4|TVP38_ASPCL Golgi apparatus membrane protein tvp38 OS=A... 38.5 0.055
sp|Q5B7A1|TVP38_EMENI Golgi apparatus membrane protein tvp38 OS=E... 38.1 0.076
sp|A7EFY0|TVP38_SCLS1 Golgi apparatus membrane protein tvp38 OS=S... 37.4 0.14
sp|Q55705|Y232_SYNY3 Uncharacterized membrane protein slr0232 OS=... 36.2 0.20
sp|A8NX72|TVP38_COPC7 Golgi apparatus membrane protein TVP38 OS=C... 36.2 0.24
sp|A2Q9P2|TVP38_ASPNC Golgi apparatus membrane protein tvp38 OS=A... 35.8 0.40
sp|O34908|YKOX_BACSU Uncharacterized membrane protein YkoX OS=Bac... 35.0 0.47
sp|Q0CT01|TVP38_ASPTN Golgi apparatus membrane protein tvp38 OS=A... 35.4 0.60
sp|P0ABP6|DEDA_ECOLI Protein DedA OS=Escherichia coli (strain K12... 34.7 0.65
sp|P0ABP7|DEDA_ECO57 Protein DedA OS=Escherichia coli O157:H7 OX=... 34.7 0.65
sp|Q57654|Y201_METJA Uncharacterized protein MJ0201 OS=Methanocal... 33.1 1.6
sp|Q48630|APL_LACLM Alkaline phosphatase-like protein OS=Lactococ... 33.5 1.6
sp|A7MB75|TM231_BOVIN Transmembrane protein 231 OS=Bos taurus OX=... 33.5 2.2
sp|P57239|Y139_BUCAI Uncharacterized membrane protein BU139 OS=Bu... 33.1 2.2
sp|P0CP22|CCR4_CRYNJ CCR4-Not complex 3'-5'-exoribonuclease subun... 33.5 2.9
sp|P0CP23|CCR4_CRYNB CCR4-Not complex 3'-5'-exoribonuclease subun... 33.5 2.9
sp|Q9CHL6|APL_LACLA Alkaline phosphatase-like protein OS=Lactococ... 32.7 3.1
sp|Q3U284|TM231_MOUSE Transmembrane protein 231 OS=Mus musculus O... 32.7 3.9
sp|P30149|YABI_ECOLI Inner membrane protein YabI OS=Escherichia c... 32.3 4.0
sp|Q759P7|TVP38_EREGS Golgi apparatus membrane protein TVP38 OS=E... 32.3 4.5
sp|Q2FZT9|UNDPT_STAA8 Putative undecaprenyl phosphate transporter... 32.0 4.6
sp|Q755Y0|AKR1_EREGS Palmitoyltransferase AKR1 OS=Eremothecium go... 32.3 5.2
sp|Q5RBT8|TM231_PONAB Transmembrane protein 231 OS=Pongo abelii O... 32.0 5.6
sp|Q89AV4|Y130_BUCBP Uncharacterized membrane protein bbp_130 OS=... 32.0 5.8
sp|Q8KA02|Y132_BUCAP Uncharacterized membrane protein BUsg_132 OS... 31.6 7.1
sp|Q5FVM1|TM231_RAT Transmembrane protein 231 OS=Rattus norvegicu... 31.6 7.5
sp|B4QL99|MAEL_DROSI Protein maelstrom OS=Drosophila simulans OX=... 31.6 8.1
sp|B4IB36|MAEL_DROSE Protein maelstrom OS=Drosophila sechellia OX... 31.6 8.1
sp|P96665|YDEH_BACSU Uncharacterized membrane protein YdeH OS=Bac... 30.8 9.4
>sp|Q5BJD5|TM41B_HUMAN Transmembrane protein 41B OS=Homo sapiens
OX=9606 GN=TMEM41B PE=1 SV=1
Length=291
Score = 414 bits (1065), Expect = 4e-146, Method: Composition-based stats.
Identities = 291/291 (100%), Positives = 291/291 (100%), Gaps = 0/291 (0%)
Query 1 MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI 60
MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI
Sbjct 1 MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI 60
Query 61 FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT
Sbjct 61 FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
Query 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT
Sbjct 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
Query 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP
Sbjct 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
Query 241 SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE
Sbjct 241 SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
>sp|Q5RBZ8|TM41B_PONAB Transmembrane protein 41B OS=Pongo abelii
OX=9601 GN=TMEM41B PE=2 SV=1
Length=291
Score = 412 bits (1060), Expect = 2e-145, Method: Composition-based stats.
Identities = 284/291 (98%), Positives = 287/291 (99%), Gaps = 0/291 (0%)
Query 1 MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI 60
MAKGRVAERSQ+GA HTTPVGDGAAGTRG AAPGSRD+QKEKSW EAGSARMSLLILVSI
Sbjct 1 MAKGRVAERSQMGADHTTPVGDGAAGTRGPAAPGSRDYQKEKSWAEAGSARMSLLILVSI 60
Query 61 FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT
Sbjct 61 FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
Query 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT
Sbjct 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
Query 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP
Sbjct 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
Query 241 SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
SFVAIKAGTTL+Q TTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE
Sbjct 241 SFVAIKAGTTLHQPTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
>sp|Q5FVN2|TM41B_RAT Transmembrane protein 41B OS=Rattus norvegicus
OX=10116 GN=Tmem41b PE=2 SV=1
Length=291
Score = 404 bits (1038), Expect = 6e-142, Method: Composition-based stats.
Identities = 271/291 (93%), Positives = 277/291 (95%), Gaps = 0/291 (0%)
Query 1 MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI 60
MAKGRVAERSQ H+TP GD A GT+G AAPG++DH KEK VEAGSAR SLLILVSI
Sbjct 1 MAKGRVAERSQTEMLHSTPAGDRAVGTQGSAAPGNKDHLKEKPCVEAGSARTSLLILVSI 60
Query 61 FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
F AAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT
Sbjct 61 FSCAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
Query 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT
Sbjct 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
Query 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP
Sbjct 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
Query 241 SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
SFVAIKAGTTLYQLTTAGEAVSWNS+FILMILA+LSILPAIFQKKLKQKFE
Sbjct 241 SFVAIKAGTTLYQLTTAGEAVSWNSVFILMILALLSILPAIFQKKLKQKFE 291
>sp|Q8K1A5|TM41B_MOUSE Transmembrane protein 41B OS=Mus musculus
OX=10090 GN=Tmem41b PE=1 SV=1
Length=291
Score = 397 bits (1020), Expect = 3e-139, Method: Composition-based stats.
Identities = 263/291 (90%), Positives = 273/291 (94%), Gaps = 0/291 (0%)
Query 1 MAKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSI 60
MAKGRVA+RS H+TP GD A T+G AAPGS+DH EK EAGSAR SLLILVSI
Sbjct 1 MAKGRVADRSPTEMLHSTPAGDRAVRTQGSAAPGSKDHLNEKPCAEAGSARTSLLILVSI 60
Query 61 FLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
F AAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT
Sbjct 61 FSCAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFAT 120
Query 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT
Sbjct 121 YIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLT 180
Query 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP
Sbjct 181 EKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPP 240
Query 241 SFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
SFVAIKAGTTL+QLTTAGEAVSW+S+FILM+LA+LSILPAIFQK+LKQKFE
Sbjct 241 SFVAIKAGTTLHQLTTAGEAVSWSSVFILMVLALLSILPAIFQKQLKQKFE 291
>sp|Q5U4K5|TM41B_XENLA Transmembrane protein 41B OS=Xenopus laevis
OX=8355 GN=tmem41b PE=2 SV=1
Length=278
Score = 368 bits (944), Expect = 5e-128, Method: Composition-based stats.
Identities = 235/287 (82%), Positives = 247/287 (86%), Gaps = 10/287 (3%)
Query 5 RVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSA 64
+V ERS G H G A K E GSARMSLLILVSIFL A
Sbjct 2 QVHERSHTGGH----TFQCNHGNEKKAPAA------GKVHSEGGSARMSLLILVSIFLCA 51
Query 65 AFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFL 124
A VMFLVYK FPQLSEEE +KVPRDMDDAKALGKVLSKYKDTFYV+VLVAYF TYIFL
Sbjct 52 ASVMFLVYKYFPQLSEEELEKIKVPRDMDDAKALGKVLSKYKDTFYVEVLVAYFTTYIFL 111
Query 125 QTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAV 184
QTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCY+LSYLVGRPVVYKYL++KA+
Sbjct 112 QTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYLLSYLVGRPVVYKYLSDKAI 171
Query 185 KWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVA 244
KWSQQVERHR+HLINYIIFLRITPFLPNWFINITSPVINVPLKVFF+GTF+GVAPPSFVA
Sbjct 172 KWSQQVERHRDHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFLGTFIGVAPPSFVA 231
Query 245 IKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
IKAGTTLYQLTTAGEAVSWNS+ ILM+LAVLSILPAIFQKKLKQKFE
Sbjct 232 IKAGTTLYQLTTAGEAVSWNSVIILMVLAVLSILPAIFQKKLKQKFE 278
>sp|A4II98|TM41B_XENTR Transmembrane protein 41B OS=Xenopus tropicalis
OX=8364 GN=tmem41b PE=2 SV=1
Length=278
Score = 366 bits (939), Expect = 4e-127, Method: Composition-based stats.
Identities = 235/287 (82%), Positives = 252/287 (88%), Gaps = 10/287 (3%)
Query 5 RVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSA 64
+V ERS G H T G+ AP + K E GSARMSLLILVSIFL A
Sbjct 2 QVHERSHTGGH-TCQCNHGSEKK----APAT-----GKVHSEGGSARMSLLILVSIFLCA 51
Query 65 AFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFL 124
A +MFLVYK+FPQLSEEER +KVPRDMDDAKALGKVLSKYKDTFYV+VLVAYF TYIFL
Sbjct 52 ASIMFLVYKHFPQLSEEEREKIKVPRDMDDAKALGKVLSKYKDTFYVEVLVAYFTTYIFL 111
Query 125 QTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAV 184
QTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASF Y+LSYLVGRPVVYKYL++KA+
Sbjct 112 QTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFSYLLSYLVGRPVVYKYLSDKAI 171
Query 185 KWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVA 244
KWSQQVERHR+HLINYIIFLRITPFLPNWFINITSPVINVPLKVFF+GTF+GVAPPSFVA
Sbjct 172 KWSQQVERHRDHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFLGTFIGVAPPSFVA 231
Query 245 IKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
IKAGTTLYQLTTAGEAVSWNS+ ILM+LAVLSILPAIFQKKLK+KFE
Sbjct 232 IKAGTTLYQLTTAGEAVSWNSVIILMVLAVLSILPAIFQKKLKKKFE 278
>sp|Q5ZIL6|TM41B_CHICK Transmembrane protein 41B OS=Gallus gallus
OX=9031 GN=TMEM41B PE=2 SV=1
Length=269
Score = 350 bits (898), Expect = 4e-121, Method: Composition-based stats.
Identities = 236/267 (88%), Positives = 248/267 (93%), Gaps = 3/267 (1%)
Query 28 RGLAAPGSRDHQK---EKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERV 84
+ AA S HQ+ K+ E GSAR SLLILVSIF AAF+MFLVYKNFPQLSEEE
Sbjct 3 QRRAAAESARHQRLLEGKAQAEGGSARTSLLILVSIFTIAAFLMFLVYKNFPQLSEEEGK 62
Query 85 NMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYP 144
+K+PRDMDDAKALGKVLSKYKDTFYVQVLVAYFATY+FLQTFAIPGSIFLSILSGFLYP
Sbjct 63 CIKIPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYVFLQTFAIPGSIFLSILSGFLYP 122
Query 145 FPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFL 204
FPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWS+QVERHREHLINYIIFL
Sbjct 123 FPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSEQVERHREHLINYIIFL 182
Query 205 RITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWN 264
RITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWN
Sbjct 183 RITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWN 242
Query 265 SIFILMILAVLSILPAIFQKKLKQKFE 291
S+F+LMILA+LSILPA+FQKKLKQKFE
Sbjct 243 SLFVLMILAILSILPALFQKKLKQKFE 269
>sp|A1A5V7|TM41B_DANRE Transmembrane protein 41B OS=Danio rerio
OX=7955 GN=tmem41b PE=2 SV=1
Length=282
Score = 347 bits (890), Expect = 1e-119, Method: Composition-based stats.
Identities = 211/290 (73%), Positives = 239/290 (82%), Gaps = 13/290 (4%)
Query 2 AKGRVAERSQLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIF 61
A R E S L P + +G +PG SARMS+L+LV IF
Sbjct 6 AGNRETESSPLVEQEPRPSKETPV-PKGAQSPG------------GASARMSILLLVVIF 52
Query 62 LSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATY 121
+A VM+LV++NFPQLSE+ER +K+P+DM+DAKALG VLSKYKDT+Y QVL+AYFATY
Sbjct 53 ACSACVMYLVFRNFPQLSEDEREKIKIPKDMEDAKALGTVLSKYKDTYYTQVLLAYFATY 112
Query 122 IFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTE 181
IFLQTFAIPGSIFLSILSG+LYPFPLALFLVCLCSGLGASFCYMLSYLVGRP+VYKYLTE
Sbjct 113 IFLQTFAIPGSIFLSILSGYLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPMVYKYLTE 172
Query 182 KAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPS 241
+A KWSQQV++HREHLINYIIFLRITPFLPNWFINITSPVINVPL VFF+GTFLGVAPPS
Sbjct 173 RAQKWSQQVDKHREHLINYIIFLRITPFLPNWFINITSPVINVPLGVFFLGTFLGVAPPS 232
Query 242 FVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKFE 291
FVAI AGTTLY+LTTAGEAVSWNS+ +L +LAV+SILP FQKKL+QK E
Sbjct 233 FVAINAGTTLYKLTTAGEAVSWNSLLVLGVLAVVSILPVCFQKKLQQKLE 282
>sp|Q9VX39|TM41_DROME Transmembrane protein 41 homolog OS=Drosophila
melanogaster OX=7227 GN=stas PE=2 SV=2
Length=320
Score = 317 bits (812), Expect = 3e-107, Method: Composition-based stats.
Identities = 131/249 (53%), Positives = 178/249 (71%), Gaps = 0/249 (0%)
Query 43 SWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVL 102
S E + + SL+I+ IF+++ M VY FP+L+ E+ ++K+PRD+ DAK L KVL
Sbjct 71 SADEKKATKKSLVIVAGIFVASLVTMCYVYAIFPELNASEKQHLKIPRDIQDAKMLAKVL 130
Query 103 SKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASF 162
+YKD +Y +V+ Y+FLQTFAIPGS+FLSIL GFLY FP+ALFL+C CS LGA+
Sbjct 131 DRYKDMYYFEVMFGVVVAYVFLQTFAIPGSLFLSILLGFLYKFPIALFLICFCSALGATL 190
Query 163 CYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVI 222
CY LS LVGR ++ + +K +WS+ VE +R+ L NY++FLR+TP LPNWFIN+ SPVI
Sbjct 191 CYTLSNLVGRRLIRHFWPKKTSEWSKHVEEYRDSLFNYMLFLRMTPILPNWFINLASPVI 250
Query 223 NVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIF 282
VPL +F +GTF GVAPPS +AI+AG TL ++T++ EA SW S+ ILM A S+LP +
Sbjct 251 GVPLHIFALGTFCGVAPPSVIAIQAGKTLQKMTSSSEAFSWTSMGILMACACASLLPGLL 310
Query 283 QKKLKQKFE 291
+ K K K E
Sbjct 311 KNKFKHKKE 319
>sp|O62126|TM41_CAEEL Transmembrane protein 41 homolog OS=Caenorhabditis
elegans OX=6239 GN=tag-175 PE=3 SV=1
Length=246
Score = 291 bits (744), Expect = 5e-98, Method: Composition-based stats.
Identities = 123/235 (52%), Positives = 169/235 (72%), Gaps = 0/235 (0%)
Query 55 LILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVL 114
+++ IF + A +F VY NFP++S +E+V++K PR+++DAK LG+VLSKYK+ Y VL
Sbjct 12 WLVLLIFATFAVSIFAVYSNFPEVSADEKVHLKYPRNLEDAKQLGRVLSKYKENNYSVVL 71
Query 115 VAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPV 174
Y+FLQ+FAIPGSIFL+ILSG+L+PF +A+ LVC CS GA+ CY +S L GR
Sbjct 72 CGVIVVYVFLQSFAIPGSIFLTILSGYLFPFYVAIVLVCSCSATGAAICYTISKLFGRSF 131
Query 175 VYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTF 234
V + E+ KW + +HR+ +NY+IFLR+TP +PNW INI SPV++VPL FF GTF
Sbjct 132 VLQKFPERIAKWQDDLSKHRDDFLNYMIFLRVTPIVPNWLINIASPVLDVPLAPFFWGTF 191
Query 235 LGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQK 289
LGVAPPSF+ I+AG+TL QL+ A SW+SI +L A+LS+ P + +KKLK
Sbjct 192 LGVAPPSFLYIQAGSTLEQLSHTSVAWSWSSIVLLTGSAILSLAPILLKKKLKSD 246
>sp|Q8L586|Y4958_ARATH Uncharacterized membrane protein At4g09580
OS=Arabidopsis thaliana OX=3702 GN=At4g09580 PE=1 SV=1
Length=287
Score = 292 bits (747), Expect = 7e-98, Method: Composition-based stats.
Identities = 94/275 (34%), Positives = 155/275 (56%), Gaps = 6/275 (2%)
Query 11 QLGAHHTTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSAAFVMFL 70
QL +P AA +GL S ++ KS +R + ++FL +F
Sbjct 15 QLVKDEESPAASSAA--KGLLNDDSPTGKRTKS-ERFPLSRWEFAVFFTVFLVFTTGLFC 71
Query 71 VYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIP 130
+Y P E +KVPR + D + L + L Y + + ++ Y +TYIF+QTF IP
Sbjct 72 IYLTMP---AAEYGKLKVPRTISDLRLLKENLGSYASEYQARFILGYCSTYIFMQTFMIP 128
Query 131 GSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQV 190
G+IF+S+L+G L+ LV L + GA C+ LS LVGRP+V EK + ++
Sbjct 129 GTIFMSLLAGALFGVVRGFVLVVLNATAGACSCFFLSKLVGRPLVNWLWPEKLRFFQAEI 188
Query 191 ERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTT 250
+ R+ L+NY++FLRITP LPN FIN++SP++++P VFF+ T +G+ P S++ ++AG
Sbjct 189 AKRRDRLLNYMLFLRITPTLPNLFINLSSPIVDIPFHVFFLATLVGLMPASYITVRAGLA 248
Query 251 LYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKK 285
L L + + + ++ +L ++ +SI PA+ ++K
Sbjct 249 LGDLRSVKDLYDFKTLSVLFLIGSISIFPALLKRK 283
>sp|Q96HV5|TM41A_HUMAN Transmembrane protein 41A OS=Homo sapiens
OX=9606 GN=TMEM41A PE=1 SV=1
Length=264
Score = 274 bits (701), Expect = 3e-91, Method: Composition-based stats.
Identities = 77/243 (32%), Positives = 141/243 (58%), Gaps = 6/243 (2%)
Query 53 SLLILVSIFLSAAFVMFLVYKNFPQ------LSEEERVNMKVPRDMDDAKALGKVLSKYK 106
LL L+ +F F ++L+ P+ E ++ P D+ + + L +VL +Y+
Sbjct 3 PLLGLLLVFAGCTFALYLLSTRLPRGRRLGSTEEAGGRSLWFPSDLAELRELSEVLREYR 62
Query 107 DTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYML 166
V + + Y++ Q FAIPGS FL++L+G L+ L L L C+ + +GA+ CY+L
Sbjct 63 KEHQAYVFLLFCGAYLYKQGFAIPGSSFLNVLAGALFGPWLGLLLCCVLTSVGATCCYLL 122
Query 167 SYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPL 226
S + G+ +V Y +K ++VE +R L +++FLR+ P PNWF+N+++P++N+P+
Sbjct 123 SSIFGKQLVVSYFPDKVALLQRKVEENRNSLFFFLLFLRLFPMTPNWFLNLSAPILNIPI 182
Query 227 KVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKL 286
FF +G+ P +F+ ++ G+ L LT+ SW+++F L+ +A+++++P KK
Sbjct 183 VQFFFSVLIGLIPYNFICVQTGSILSTLTSLDALFSWDTVFKLLAIAMVALIPGTLIKKF 242
Query 287 KQK 289
QK
Sbjct 243 SQK 245
>sp|Q08D99|TM41A_BOVIN Transmembrane protein 41A OS=Bos taurus
OX=9913 GN=TMEM41A PE=2 SV=1
Length=264
Score = 269 bits (688), Expect = 3e-89, Method: Composition-based stats.
Identities = 81/243 (33%), Positives = 147/243 (60%), Gaps = 6/243 (2%)
Query 53 SLLILVSIFLSAAFVMFLVYKNFPQ----LSEEERVN--MKVPRDMDDAKALGKVLSKYK 106
SLL L+ +F + F ++L+ P+ +S EE + + P D+ + + L +VL +Y+
Sbjct 3 SLLGLLLVFAGSTFALYLLSTRLPRASTLVSAEESGDRSLWFPSDLAELRELSEVLREYR 62
Query 107 DTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYML 166
V V + + + Y++ Q+FAIPGS FL++L+G L+ L L L C+ + +GA+ CY+L
Sbjct 63 KEHQVYVFLLFCSAYLYKQSFAIPGSSFLNVLAGALFGPWLGLLLCCVLTSVGATGCYLL 122
Query 167 SYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPL 226
S + G+ +V Y +K ++VE +R L +++FLR+ P PNWF+N+++P++N+P+
Sbjct 123 SSVFGKQLVVFYFPDKVALLQKKVEENRNGLFFFLLFLRLFPMTPNWFLNLSAPILNIPI 182
Query 227 KVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKL 286
FF +G+ P +F+ ++ G+ L LT+ SW + F L+ +A+++++P KK
Sbjct 183 VQFFFSVLIGLIPYNFICVQTGSILSTLTSLDALFSWETAFKLLAIALVALVPGTLIKKF 242
Query 287 KQK 289
QK
Sbjct 243 SQK 245
>sp|Q9D8U2|TM41A_MOUSE Transmembrane protein 41A OS=Mus musculus
OX=10090 GN=Tmem41a PE=2 SV=1
Length=264
Score = 264 bits (675), Expect = 2e-87, Method: Composition-based stats.
Identities = 74/232 (32%), Positives = 134/232 (58%), Gaps = 6/232 (3%)
Query 64 AAFVMFLVYKNFP------QLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAY 117
F ++L+ P E E ++ P D+ + + L +VL +Y+ V + +
Sbjct 14 CTFALYLLSTRLPLGPRLAAAGEPEGRSLWFPSDLAELRELSEVLREYRKEHQAYVFLLF 73
Query 118 FATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYK 177
+ Y++ Q FAIPGS FL++L+G L+ L L L C+ + +GA+ CY+LS L G+ +V
Sbjct 74 CSAYLYKQGFAIPGSSFLNVLAGALFGPWLGLLLCCVLTSVGATGCYLLSSLFGKQLVIS 133
Query 178 YLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGV 237
Y +K ++VE +R L +++FLR+ P PNWF+N+++P++N+P+ FF +G+
Sbjct 134 YFPDKVALLQKKVEENRNSLFFFLLFLRLFPMTPNWFLNLSAPILNIPIVQFFFSVLIGL 193
Query 238 APPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQK 289
P +F+ ++ G+ L LT+ SW ++ L+ +A+++++P KK QK
Sbjct 194 IPYNFICVQTGSILSTLTSLDALFSWETVLKLLAIALVALVPGTLIKKFSQK 245
>sp|Q8MXN7|TM41_DICDI Transmembrane protein 41 homolog OS=Dictyostelium
discoideum OX=44689 GN=DDB_G0275543 PE=3 SV=2
Length=334
Score = 266 bits (680), Expect = 5e-87, Method: Composition-based stats.
Identities = 102/238 (43%), Positives = 154/238 (65%), Gaps = 0/238 (0%)
Query 50 ARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTF 109
A + L +LV +F + V+ ++ NFP LS + + +++P++ D K L +LS+Y D
Sbjct 95 APLPLWLLVIVFGVSISVIVFLFLNFPSLSPQHKQLIRLPKNFKDVKLLSDILSQYTDDN 154
Query 110 YVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYL 169
Y V+ + Y FLQ F+IPGS+FLS LSG L+ + LVC + LGA+F Y++SY
Sbjct 155 YFIVITTFGVIYTFLQAFSIPGSVFLSFLSGGLFGLKVGFPLVCFVATLGATFSYLISYY 214
Query 170 VGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVF 229
+GR +V K +K +S + + R++L+NYI+FLRITPFLPNWFIN+ SP+++VP+ F
Sbjct 215 IGRNLVRKLFPDKLKLFSDSLSQKRDNLLNYIVFLRITPFLPNWFINLASPLLDVPIHTF 274
Query 230 FIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLK 287
IGTF+G+ P +F+A+KAG + + + SI + LA+LSILP + QKKLK
Sbjct 275 AIGTFIGIMPATFLAVKAGIQIQNIQNPSDIFDLKSILTMAALALLSILPTLIQKKLK 332
>sp|Q502G2|T41AA_DANRE Transmembrane protein 41A-A OS=Danio rerio
OX=7955 GN=tmem41aa PE=2 SV=1
Length=281
Score = 254 bits (649), Expect = 4e-83, Method: Composition-based stats.
Identities = 71/214 (33%), Positives = 128/214 (60%), Gaps = 0/214 (0%)
Query 76 PQLSEEERVNMKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFL 135
P E +K P D+D+ K + ++L YK VL+ + + Y++ Q FAIPGS FL
Sbjct 49 PSEMETASSRLKFPSDLDELKEMAELLQFYKTEHTGYVLLLFCSAYLYKQAFAIPGSSFL 108
Query 136 SILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHRE 195
+IL+G L+ L L C+ + +GA+ C++LS G+ + K +K ++VE +R
Sbjct 109 NILAGALFGTWFGLLLTCVLTTVGATLCFLLSQAFGKHHIVKLFPDKVAMLQKKVEENRS 168
Query 196 HLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLT 255
L +++FLR P PNWF+N+TSP++N+P+ +FF+ F+G+ P +F+ ++ G+ L Q++
Sbjct 169 SLFFFLLFLRFFPMSPNWFLNMTSPILNIPVTLFFMAVFIGLMPYNFICVQTGSMLSQIS 228
Query 256 TAGEAVSWNSIFILMILAVLSILPAIFQKKLKQK 289
+ + SW+ + L++ A +++LP +K +
Sbjct 229 SLDDLFSWSVVLKLLLTACVALLPGALIRKYSTR 262
>sp|Q6NV38|T41AB_DANRE Transmembrane protein 41A-B OS=Danio rerio
OX=7955 GN=tmem41ab PE=2 SV=1
Length=278
Score = 245 bits (625), Expect = 1e-79, Method: Composition-based stats.
Identities = 71/239 (30%), Positives = 135/239 (56%), Gaps = 4/239 (2%)
Query 55 LILVSIFLSAAFVMFLVYKNFPQLSEEE----RVNMKVPRDMDDAKALGKVLSKYKDTFY 110
L L+S FL V+ P+ +++E + +K P D+++ + L ++L YK
Sbjct 18 LYLLSAFLPPGPRAIRVHDTGPEHTDDEPEEKVLRLKFPSDLEELRELAELLKFYKTEHT 77
Query 111 VQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLV 170
V + + + Y++ Q+FAIPGS FL++LSG L+ L + C + +G++ CY+LS
Sbjct 78 GYVFILFCSAYLYKQSFAIPGSSFLNMLSGALFGPLHGLIIACTLTTVGSTNCYLLSRTF 137
Query 171 GRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFF 230
G+ + + EK + VE +R L +++FLR P PNWF+N+TSP++N+P+ +FF
Sbjct 138 GKRHIVRLFPEKVAMLQRMVEENRSSLFFFLLFLRFFPMTPNWFLNVTSPILNIPIPIFF 197
Query 231 IGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQK 289
+G+ P +F+ + G L ++ + + SW ++ L+++A +++LP ++ +
Sbjct 198 FSILIGLIPYNFICVHTGAVLSEINSLDDIFSWFTLLQLLLIACVALLPGALIRRYSKD 256
>sp|P76221|YDJZ_ECOLI TVP38/TMEM64 family inner membrane protein
YdjZ OS=Escherichia coli (strain K12) OX=83333 GN=ydjZ PE=1
SV=1
Length=235
Score = 153 bits (387), Expect = 3e-44, Method: Composition-based stats.
Identities = 69/246 (28%), Positives = 106/246 (43%), Gaps = 40/246 (16%)
Query 39 QKEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPR-DMDDAKA 97
Q K W R++L+IL+ F M L + P + E +N V D +
Sbjct 5 QSRKIWYY----RITLIILL-------FAMLLAWALLPGV--HEFINRSVAAFAAVDQQG 51
Query 98 LGKVLSKYKD-----TFYVQVLVAYFATY-IFLQTFAIPGSIFLSILSGFLYPFPLALFL 151
+ + + Y +F + +L A A FL TFA S+F + G L
Sbjct 52 IERFIQSYGALAAVVSFLLMILQAIAAPLPAFLITFA-NASLFGAFWGGLLS-------- 102
Query 152 VCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQ--VERHREHLINYIIFLRITPF 209
S GA+ C+ ++ ++GR VV K LT K V S R+ +H I + R+ PF
Sbjct 103 -WTSSMAGAALCFFIARVMGREVVEK-LTGKTVLDSMDGFFTRYGKHTI---LVCRLLPF 157
Query 210 LPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFIL 269
+P I+ + + ++ + FFI T LG P + V AG+ L T G +FIL
Sbjct 158 VPFDPISYAAGLTSIRFRSFFIATGLGQLPATIVYSWAGSML----TGGTFWFVTGLFIL 213
Query 270 MILAVL 275
L V+
Sbjct 214 FALTVV 219
>sp|Q55909|Y305_SYNY3 TVP38/TMEM64 family membrane protein slr0305
OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
OX=1111708 GN=slr0305 PE=3 SV=1
Length=209
Score = 66.2 bits (160), Expect = 1e-11, Method: Composition-based stats.
Identities = 37/146 (25%), Positives = 68/146 (47%), Gaps = 3/146 (2%)
Query 115 VAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPV 174
+A+ Y +PGSI L++ +G ++ L V + + LGA+ +++ + R
Sbjct 21 IAFMLLYTVATVVFLPGSI-LTLGAGVVFGVILGSIYVFIGATLGATAAFLVGRYLARGW 79
Query 175 VYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTF 234
V K + K+ E + + +I R++P P +N + NV LK + IG+
Sbjct 80 VAKKIAGN-QKFKAIDEAVGKEGLKIVILTRLSPVFPFNLLNYAYGITNVSLKDYVIGS- 137
Query 235 LGVAPPSFVAIKAGTTLYQLTTAGEA 260
LG+ P + + + G+ L T G A
Sbjct 138 LGMIPGTIMYVYIGSLAGSLATLGTA 163
>sp|P67118|Y1528_MYCBO TVP38/TMEM64 family membrane protein Mb1528c
OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
OX=233413 GN=BQ2027_MB1528C PE=3 SV=1
Length=252
Score = 55.8 bits (133), Expect = 7e-08, Method: Composition-based stats.
Identities = 29/147 (20%), Positives = 59/147 (40%), Gaps = 4/147 (3%)
Query 102 LSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGAS 161
L + + +A+ + + P + F ++ +G L+ + +F+ + S A
Sbjct 57 LRDWAKSLGAWFPLAFLLVHTVVTVPPFPRTAF-TLAAGLLFGSVVGVFIAVVGSTASAV 115
Query 162 FCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPV 221
+L G + + +A+ ++ ER RE I+ LR+ P +P IN +
Sbjct 116 IAMLLVRATGWQL-NSLVRRRAI--NRLDERLRERGWLAILSLRLIPVVPFAAINYAAGA 172
Query 222 INVPLKVFFIGTFLGVAPPSFVAIKAG 248
V + F T G+ P + + G
Sbjct 173 SGVRILSFAWATLAGLLPGTAAVVILG 199
>sp|P9WFS3|Y1491_MYCTU TVP38/TMEM64 family membrane protein Rv1491c
OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
OX=83332 GN=Rv1491c PE=3 SV=1
Length=252
Score = 55.8 bits (133), Expect = 7e-08, Method: Composition-based stats.
Identities = 29/147 (20%), Positives = 59/147 (40%), Gaps = 4/147 (3%)
Query 102 LSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGAS 161
L + + +A+ + + P + F ++ +G L+ + +F+ + S A
Sbjct 57 LRDWAKSLGAWFPLAFLLVHTVVTVPPFPRTAF-TLAAGLLFGSVVGVFIAVVGSTASAV 115
Query 162 FCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPV 221
+L G + + +A+ ++ ER RE I+ LR+ P +P IN +
Sbjct 116 IAMLLVRATGWQL-NSLVRRRAI--NRLDERLRERGWLAILSLRLIPVVPFAAINYAAGA 172
Query 222 INVPLKVFFIGTFLGVAPPSFVAIKAG 248
V + F T G+ P + + G
Sbjct 173 SGVRILSFAWATLAGLLPGTAAVVILG 199
>sp|P9WFS2|Y1491_MYCTO TVP38/TMEM64 family membrane protein MT1538
OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
OX=83331 GN=MT1538 PE=3 SV=1
Length=252
Score = 55.8 bits (133), Expect = 7e-08, Method: Composition-based stats.
Identities = 29/147 (20%), Positives = 59/147 (40%), Gaps = 4/147 (3%)
Query 102 LSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGAS 161
L + + +A+ + + P + F ++ +G L+ + +F+ + S A
Sbjct 57 LRDWAKSLGAWFPLAFLLVHTVVTVPPFPRTAF-TLAAGLLFGSVVGVFIAVVGSTASAV 115
Query 162 FCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPV 221
+L G + + +A+ ++ ER RE I+ LR+ P +P IN +
Sbjct 116 IAMLLVRATGWQL-NSLVRRRAI--NRLDERLRERGWLAILSLRLIPVVPFAAINYAAGA 172
Query 222 INVPLKVFFIGTFLGVAPPSFVAIKAG 248
V + F T G+ P + + G
Sbjct 173 SGVRILSFAWATLAGLLPGTAAVVILG 199
>sp|P76219|YDJX_ECOLI TVP38/TMEM64 family membrane protein YdjX
OS=Escherichia coli (strain K12) OX=83333 GN=ydjX PE=3 SV=2
Length=236
Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats.
Identities = 30/164 (18%), Positives = 66/164 (40%), Gaps = 10/164 (6%)
Query 92 MDDAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFL 151
+ D L ++ + Y ++ + + L +PGSI L I G ++ L L
Sbjct 30 LTDLPHLQTLIRQSGFFGYSLYILLFIIATLLL----LPGSI-LVIAGGIVFGPLLGTLL 84
Query 152 VCLCSGLGASFCYMLSYLVGRPVVYKYL--TEKAVKWSQQVERHREHLINYIIFLRITPF 209
+ + L +S ++L+ +GR ++ KY+ + + + R+ I+++I R+ P
Sbjct 85 SLIAATLASSCSFLLARWLGRDLLLKYVGHSNTFQAIEKGIARNG---IDFLILTRLIPL 141
Query 210 LPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQ 253
P N + + + + + L P + + L
Sbjct 142 FPYNIQNYAYGLTTIAFWPYTLISALTTLPGIVIYTVMASDLAN 185
>sp|P06568|YTXB_BACSU TVP38/TMEM64 family membrane protein YtxB
OS=Bacillus subtilis (strain 168) OX=224308 GN=ytxB PE=3 SV=1
Length=213
Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats.
Identities = 41/183 (22%), Positives = 75/183 (41%), Gaps = 19/183 (10%)
Query 115 VAYFATYIFL-QTFAIPGSIF----LSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYL 169
FA +F+ + P +F +SI G + L S ++ + + L
Sbjct 41 FGVFAPLMFIGISIVRPLVLFPVSVISIAGGLAFGPLLGTLYTLFGSMCASAVSFFAAGL 100
Query 170 VGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVF 229
Y E+ +Q+E + YI LRI P F++ + + NV +
Sbjct 101 FSAKKNGHY--ERLEAIQKQMEDNG---FFYIFLLRILPIN-FDFVSYAAGLSNVKALPY 154
Query 230 FIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSI-LPAIFQKKLKQ 288
F T +G+ P + L L + A + + F+++ L ++ I LP IF+KK++
Sbjct 155 FAATAVGIIPGTI-------ALNVLGASFLAGNLPAFFMVLALYIVFISLPFIFRKKMQN 207
Query 289 KFE 291
F+
Sbjct 208 LFQ 210
>sp|P54449|YQED_BACSU Uncharacterized protein YqeD OS=Bacillus
subtilis (strain 168) OX=224308 GN=yqeD PE=4 SV=1
Length=208
Score = 52.8 bits (125), Expect = 5e-07, Method: Composition-based stats.
Identities = 27/146 (18%), Positives = 56/146 (38%), Gaps = 1/146 (1%)
Query 127 FAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKW 186
F I ++ L+G ++ +++ S LG + L+ R K +
Sbjct 50 FPIVPFALIAALNGAVFGTANGIWITLTGSMLGTILLFFLARYSFRDWARKKVQAYPAIQ 109
Query 187 SQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIK 246
S + ++ ++ R+ P +P+ +N+ + V VFF + +G P V
Sbjct 110 SYEASFNKNA-FTAVLLGRLIPVIPSLVMNVICGLSQVRWHVFFFASLIGKIPNIVVVTI 168
Query 247 AGTTLYQLTTAGEAVSWNSIFILMIL 272
AG ++ I I+M++
Sbjct 169 AGANFTSNKLLSISIYGTYILIIMLV 194
>sp|Q6BQJ1|TVP38_DEBHA Golgi apparatus membrane protein TVP38
OS=Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC
21394 / JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=TVP38
PE=3 SV=1
Length=383
Score = 52.0 bits (123), Expect = 2e-06, Method: Composition-based stats.
Identities = 36/190 (19%), Positives = 79/190 (42%), Gaps = 11/190 (6%)
Query 109 FYVQVLVAYFATYIFLQTFA-IPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLS 167
++ T +F+ F + G LS+L+G +Y F L+ S G+ +++
Sbjct 93 HGLKFGQGLLFTLVFMVGFPPLLGFSALSMLAGMVYGFVHGWILLACASISGSFCSFLVF 152
Query 168 YLVGRPVVYKYL--TEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINIT-SPVINV 224
+ + + +K +S+ + + + ++ LR+ P LP N + + +
Sbjct 153 RYLLHSRAERLMNSNKKFRAFSEILRE--DSSLFILVLLRLCP-LPYSLSNGALAAIPEL 209
Query 225 PLKVFFIGTFLGVAPPSFVAIKAGTTLYQL---TTAGEAVSWNSIFILMILAVLSILPAI 281
P +F+ + + +P + I G L +L T + + I++ A S+ I
Sbjct 210 PATTYFLASLI-TSPKLMIHIFVGHKLKELGDDTKGKSTHLIDILSIIITGAAASLTTYI 268
Query 282 FQKKLKQKFE 291
K+++K E
Sbjct 269 IYNKMQRKLE 278
>sp|Q3U145|TMM64_MOUSE Transmembrane protein 64 OS=Mus musculus
OX=10090 GN=Tmem64 PE=1 SV=1
Length=381
Score = 50.5 bits (119), Expect = 8e-06, Method: Composition-based stats.
Identities = 33/153 (22%), Positives = 68/153 (44%), Gaps = 13/153 (8%)
Query 131 GSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYL------TEKAV 184
G I L++ +G+LY F L + L+ + +G ++++V + ++ ++ ++K
Sbjct 178 GYIVLNVAAGYLYGFVLGMGLMVVGVLIGT----FIAHVVCKRLLTAWVAARIQNSDKLS 233
Query 185 KWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVA 244
+ VE + + R+TP P N + +VPL + + + G+ P +
Sbjct 234 AVIRVVE--GGSGLKVVALARLTPI-PFGLQNAVFSITDVPLPSYLMASSAGLLPTQLLN 290
Query 245 IKAGTTLYQLTTAGEAVSWNSIFILMILAVLSI 277
GTTL + S + F+ + V+SI
Sbjct 291 SYLGTTLRTMEDVIAEQSLSGYFVFCLQIVISI 323
>sp|Q6YI46|TMM64_HUMAN Transmembrane protein 64 OS=Homo sapiens
OX=9606 GN=TMEM64 PE=1 SV=2
Length=380
Score = 45.1 bits (105), Expect = 4e-04, Method: Composition-based stats.
Identities = 31/153 (20%), Positives = 67/153 (44%), Gaps = 13/153 (8%)
Query 131 GSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYL------TEKAV 184
G I L++ +G+LY F L + L+ +G ++++V + ++ ++ +EK
Sbjct 177 GYIVLNVAAGYLYGFVLGMGLM----MVGVLIGTFIAHVVCKRLLTAWVAARIQSSEKLS 232
Query 185 KWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVA 244
+ VE + + R+TP P N + ++ L + + + +G+ P +
Sbjct 233 AVIRVVE--GGSGLKVVALARLTPI-PFGLQNAVFSITDLSLPNYLMASSVGLLPTQLLN 289
Query 245 IKAGTTLYQLTTAGEAVSWNSIFILMILAVLSI 277
GTTL + S + F+ + ++SI
Sbjct 290 SYLGTTLRTMEDVIAEQSVSGYFVFCLQIIISI 322
>sp|O07559|YHJE_BACSU Uncharacterized membrane protein YhjE OS=Bacillus
subtilis (strain 168) OX=224308 GN=yhjE PE=4 SV=1
Length=207
Score = 42.4 bits (98), Expect = 0.002, Method: Composition-based stats.
Identities = 21/116 (18%), Positives = 41/116 (35%), Gaps = 5/116 (4%)
Query 143 YPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTE--KAVKWSQQVERHREHLINY 200
+ L S G+ +++ G+ + ++ K VERH
Sbjct 55 FGLWEGFILSWAGSTAGSILVFLIVRQYGQRKLLGFIRSHPSVRKLMLWVERHG---FGP 111
Query 201 IIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTT 256
+ L PF P+ +N+ + + + + F + G F+ G L+ L T
Sbjct 112 MFLLLCFPFTPSAAVNVVAGLSRIGTRPFILAAASGKLVMIFMISFIGYDLHALIT 167
>sp|Q2UUJ9|TVP38_ASPOR Golgi apparatus membrane protein tvp38
OS=Aspergillus oryzae (strain ATCC 42149 / RIB 40) OX=510516
GN=tvp38 PE=3 SV=2
Length=414
Score = 41.2 bits (95), Expect = 0.008, Method: Composition-based stats.
Identities = 37/188 (20%), Positives = 79/188 (42%), Gaps = 10/188 (5%)
Query 98 LGKVLSKYKDTFYVQVLVAYFATYIFLQTFA--IPGSIFLSILSGFLYPFPLALFLVCLC 155
LG V +++ + ++ +F +F + S F +I SG+++ FL
Sbjct 107 LGPVAEQWEQSVVAYTVLWLC---VFFVSFPPLVGWSTFGTI-SGYIFGVWKGWFLYASA 162
Query 156 SGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFI 215
+ LG++ +++S + V + + + + + L + +R+ P LP
Sbjct 163 TVLGSTCSFVVSRTILSKFVNRMMERDKRFAALALTLKYDGL-KLLCMIRLCP-LPYSVC 220
Query 216 NIT-SPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAV 274
N S V ++ + T + V P V G+ + L+ GE +S S + +I +
Sbjct 221 NGAVSTFPTVQPLMYGLATAI-VTPKLLVPAFVGSRIRLLSEKGEEMSAGSKAVNIISII 279
Query 275 LSILPAIF 282
+++ IF
Sbjct 280 VTVAIGIF 287
>sp|P67116|Y641_MYCBO TVP38/TMEM64 family membrane protein Mb0641c
OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
OX=233413 GN=BQ2027_MB0641C PE=3 SV=1
Length=246
Score = 40.8 bits (94), Expect = 0.008, Method: Composition-based stats.
Identities = 35/207 (17%), Positives = 70/207 (34%), Gaps = 22/207 (11%)
Query 47 AGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYK 106
A ++R ++ + +F MF + ++ + +++ R A L
Sbjct 8 APTSRRRHIVRLVVFAGFLVGMFYL------VAATDVIDVAAVRGAVSATGPAAPL---- 57
Query 107 DTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYML 166
Y L +PG I L+ SG L+ + +F+ + A ++
Sbjct 58 ---------TYVVVSAVLGALFVPGPI-LAASSGLLFGPLVGVFVTLGATVGTAVVASLV 107
Query 167 SYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPL 226
GR L + + + + ++ R P + + F + VPL
Sbjct 108 GRRAGRASARALLGGERADRTDALIERCG--LWAVVGQRFVPGISDAFASYAFGTFGVPL 165
Query 227 KVFFIGTFLGVAPPSFVAIKAGTTLYQ 253
+G F+G AP +F G +
Sbjct 166 WQMAVGAFIGSAPRAFAYTALGAAIGD 192
>sp|P9WFS5|Y625_MYCTU TVP38/TMEM64 family membrane protein Rv0625c
OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
OX=83332 GN=Rv0625c PE=1 SV=1
Length=246
Score = 40.8 bits (94), Expect = 0.008, Method: Composition-based stats.
Identities = 35/207 (17%), Positives = 70/207 (34%), Gaps = 22/207 (11%)
Query 47 AGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYK 106
A ++R ++ + +F MF + ++ + +++ R A L
Sbjct 8 APTSRRRHIVRLVVFAGFLVGMFYL------VAATDVIDVAAVRGAVSATGPAAPL---- 57
Query 107 DTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYML 166
Y L +PG I L+ SG L+ + +F+ + A ++
Sbjct 58 ---------TYVVVSAVLGALFVPGPI-LAASSGLLFGPLVGVFVTLGATVGTAVVASLV 107
Query 167 SYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPL 226
GR L + + + + ++ R P + + F + VPL
Sbjct 108 GRRAGRASARALLGGERADRTDALIERCG--LWAVVGQRFVPGISDAFASYAFGTFGVPL 165
Query 227 KVFFIGTFLGVAPPSFVAIKAGTTLYQ 253
+G F+G AP +F G +
Sbjct 166 WQMAVGAFIGSAPRAFAYTALGAAIGD 192
>sp|P9WFS4|Y625_MYCTO TVP38/TMEM64 family membrane protein MT0653
OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
OX=83331 GN=MT0653 PE=3 SV=1
Length=246
Score = 40.8 bits (94), Expect = 0.008, Method: Composition-based stats.
Identities = 35/207 (17%), Positives = 70/207 (34%), Gaps = 22/207 (11%)
Query 47 AGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVPRDMDDAKALGKVLSKYK 106
A ++R ++ + +F MF + ++ + +++ R A L
Sbjct 8 APTSRRRHIVRLVVFAGFLVGMFYL------VAATDVIDVAAVRGAVSATGPAAPL---- 57
Query 107 DTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYML 166
Y L +PG I L+ SG L+ + +F+ + A ++
Sbjct 58 ---------TYVVVSAVLGALFVPGPI-LAASSGLLFGPLVGVFVTLGATVGTAVVASLV 107
Query 167 SYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPL 226
GR L + + + + ++ R P + + F + VPL
Sbjct 108 GRRAGRASARALLGGERADRTDALIERCG--LWAVVGQRFVPGISDAFASYAFGTFGVPL 165
Query 227 KVFFIGTFLGVAPPSFVAIKAGTTLYQ 253
+G F+G AP +F G +
Sbjct 166 WQMAVGAFIGSAPRAFAYTALGAAIGD 192
>sp|A5DH87|TVP38_PICGU Golgi apparatus membrane protein TVP38
OS=Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM
6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) OX=294746 GN=TVP38
PE=3 SV=2
Length=349
Score = 40.8 bits (94), Expect = 0.010, Method: Composition-based stats.
Identities = 35/167 (21%), Positives = 68/167 (41%), Gaps = 12/167 (7%)
Query 131 GSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLV----GRPVVYKYLTEKAVKW 186
G LS+L+G +Y FP L+ S G+ +++ G +V EK +
Sbjct 108 GYSALSLLAGMVYGFPYGWPLLASASVSGSFVAFLVFRYFLRSQGERLVNS--NEKFRAF 165
Query 187 SQQVERHREHLINYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIK 246
++ + + + ++ +R+ P LP N I ++G + +P + +
Sbjct 166 AEILRE--DSSLFLLVLIRLCP-LPYSLSNGALAAIPELSAWVYLGASVITSPKMLIHLF 222
Query 247 AGTTLYQLTTAGEAVS---WNSIFILMILAVLSILPAIFQKKLKQKF 290
G + + A S + I IL+ A S+ I +K++QK
Sbjct 223 VGHKIKEFGDAKTDTSTKIIDVISILVTGAAASLTTFIIYRKMQQKL 269
>sp|Q57819|Y374_METJA Uncharacterized protein MJ0374 OS=Methanocaldococcus
jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1
/ JCM 10045 / NBRC 100440) OX=243232 GN=MJ0374 PE=4 SV=1
Length=330
Score = 40.8 bits (94), Expect = 0.010, Method: Composition-based stats.
Identities = 33/160 (21%), Positives = 59/160 (37%), Gaps = 6/160 (4%)
Query 102 LSKYKDTFYVQV-LVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGA 160
+++Y Y + + T F+Q IP +F+ S F ++ + + + LG
Sbjct 12 MAEYLVNNYGYIGIFIISFTEAFIQ--PIPPDVFIIGASFFGLNPIISAIVATIGTTLGG 69
Query 161 SFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFINITSP 220
F Y L +G P+ K EK + + E Y + + LP I S
Sbjct 70 LFGYFLGDKLGHPIFIKLFGEK---YLHKGEEFFNKYGVYGVVIAGFSPLPYKVIAWLSG 126
Query 221 VINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEA 260
+ + +F +GT +G P G L + +
Sbjct 127 IFEMHKLLFTVGTIIGRLPRFLAVAYFGDVLGNINRLSDI 166
>sp|O31823|UPTA_BACSU Undecaprenyl phosphate transporter A OS=Bacillus
subtilis (strain 168) OX=224308 GN=uptA PE=2 SV=1
Length=198
Score = 38.9 bits (89), Expect = 0.021, Method: Composition-based stats.
Identities = 37/183 (20%), Positives = 67/183 (37%), Gaps = 18/183 (10%)
Query 115 VAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGAS----FCYMLSYLV 170
+ Y I L IP I L+ + + + +G + F Y +
Sbjct 15 MGYAGIAIGLMIEIIPSEIVLAYGGYMVSEGTIGFIGAIIAGVIGGTIAQIFIYWIGRYG 74
Query 171 GRPVVYKYLTEKAVKWSQQ--------VERHREHLINYIIFLRITPFLPNWFINITSPVI 222
GRP + KY K + + +++ ++ R P + + I+I + +
Sbjct 75 GRPFLDKY--GKYLLIKKHHIDMSENWFQKYGAGVVFSA---RFIPVVRH-AISIPAGIA 128
Query 223 NVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSILPAIF 282
+P F + T L + P S + + G L E ++ +MILAV+ I
Sbjct 129 RMPFLKFVVLTVLAIIPWSILFVYLGIQLGSQWDDVENIAGTYTTPIMILAVVVIALYFV 188
Query 283 QKK 285
KK
Sbjct 189 IKK 191
>sp|A0A0H3H138|DEDA_KLEPH DedA family protein OS=Klebsiella pneumoniae
subsp. pneumoniae (strain HS11286) OX=1125630 GN=dedA
PE=1 SV=1
Length=219
Score = 38.5 bits (88), Expect = 0.032, Method: Composition-based stats.
Identities = 38/201 (19%), Positives = 75/201 (37%), Gaps = 27/201 (13%)
Query 98 LGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFP-------LALF 150
L +++++Y Y + + F + T +PG L ++G L P L +
Sbjct 18 LAELVAQYGVWVYAILFLILFCETGLVVTPFLPGDSLL-FVAGALSALPTNDLNVHLMVL 76
Query 151 LVCLCSGLGASFCYMLSYLVGRPV--------VYKYLTEKAVKWSQQVERHREHLINYII 202
L+ + + +G + Y + L G + + +K + ERH I I
Sbjct 77 LMVIAAIVGDAVNYTIGRLFGEKLFSNPNSKIFRRSYLDKTHSF---YERHGGKTI---I 130
Query 203 FLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVS 262
R P + F + + ++ + F +G + AG L E
Sbjct 131 LARFVPIVRT-FAPFVAGMGHMSYRHFAAYNVVGALLWVLLFTYAGYLFGDLPVVQE--- 186
Query 263 WNSIFILMILAVLSILPAIFQ 283
N +++ + VLS+LP + +
Sbjct 187 -NLKLLIVAIIVLSVLPGVIE 206
>sp|A1CW44|TVP38_NEOFI Golgi apparatus membrane protein tvp38
OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65
/ FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117
GN=tvp38 PE=3 SV=1
Length=418
Score = 38.9 bits (89), Expect = 0.043, Method: Composition-based stats.
Identities = 19/114 (17%), Positives = 47/114 (41%), Gaps = 7/114 (6%)
Query 98 LGKVLSKYKDTFYVQVLVAYFATYIFLQTFA--IPGSIFLSILSGFLYPFPLALFLVCLC 155
LG V K++ ++ ++ +F +F + S F +I +GF++ L
Sbjct 109 LGPVAEKWEQSWLAFFVLWLC---VFFVSFPPLVGWSTFGTI-AGFIFGIWKGWILYATA 164
Query 156 SGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPF 209
+ LG++ +++S + V + + + + + L + +R+ P
Sbjct 165 TVLGSTCSFIVSRTILSKFVNRMMERDKRFAALALTLKYDGL-KLLCMIRLCPL 217
>sp|Q4WQJ2|TVP38_ASPFU Golgi apparatus membrane protein tvp38
OS=Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355
/ FGSC A1100 / Af293) OX=330879 GN=tvp38 PE=3 SV=1
Length=418
Score = 38.9 bits (89), Expect = 0.046, Method: Composition-based stats.
Identities = 21/114 (18%), Positives = 47/114 (41%), Gaps = 7/114 (6%)
Query 98 LGKVLSKYKDTFYVQVLVAYFATYIFLQTFA--IPGSIFLSILSGFLYPFPLALFLVCLC 155
LG V K++ ++ ++ +F +F + S F +I SGF+Y L
Sbjct 109 LGPVAEKWEQSWLAFFVLWLC---VFFVSFPPLVGWSTFGTI-SGFIYGIWKGWILYATA 164
Query 156 SGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPF 209
+ LG++ +++S + V + + + + + L + +R+ P
Sbjct 165 TVLGSTCSFIVSRTILSKFVNRMMERDKRFAALALTLKYDGL-KLLCMIRLCPL 217
>sp|B0Y4Q5|TVP38_ASPFC Golgi apparatus membrane protein tvp38
OS=Aspergillus fumigatus (strain CBS 144.89 / FGSC A1163 / CEA10)
OX=451804 GN=tvp38 PE=3 SV=1
Length=418
Score = 38.9 bits (89), Expect = 0.047, Method: Composition-based stats.
Identities = 21/114 (18%), Positives = 47/114 (41%), Gaps = 7/114 (6%)
Query 98 LGKVLSKYKDTFYVQVLVAYFATYIFLQTFA--IPGSIFLSILSGFLYPFPLALFLVCLC 155
LG V K++ ++ ++ +F +F + S F +I SGF+Y L
Sbjct 109 LGPVAEKWEQSWLAFFVLWLC---VFFVSFPPLVGWSTFGTI-SGFIYGIWKGWILYATA 164
Query 156 SGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPF 209
+ LG++ +++S + V + + + + + L + +R+ P
Sbjct 165 TVLGSTCSFIVSRTILSKFVNRMMERDKRFAALALTLKYDGL-KLLCMIRLCPL 217
>sp|A1CIM4|TVP38_ASPCL Golgi apparatus membrane protein tvp38
OS=Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM
816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=tvp38
PE=3 SV=1
Length=419
Score = 38.5 bits (88), Expect = 0.055, Method: Composition-based stats.
Identities = 18/115 (16%), Positives = 47/115 (41%), Gaps = 6/115 (5%)
Query 95 AKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCL 154
+ + + + K F+V L +F ++ L ++ G++ +GF++ L
Sbjct 110 LEPVAETWEQSKLAFFVLWLCVFFVSFPPLVGWSTFGTV-----AGFIFGIWKGWLLYAT 164
Query 155 CSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPF 209
+ LG++ +++S V V + + + + + L + +R+ P
Sbjct 165 ATVLGSTCSFIVSRTVLSKFVNRMMERDKRFAALALTLKYDGL-KLLCMIRLCPL 218
>sp|Q5B7A1|TVP38_EMENI Golgi apparatus membrane protein tvp38
OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46
/ NRRL 194 / M139) OX=227321 GN=tvp38 PE=3 SV=1
Length=410
Score = 38.1 bits (87), Expect = 0.076, Method: Composition-based stats.
Identities = 33/152 (22%), Positives = 62/152 (41%), Gaps = 5/152 (3%)
Query 132 SIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVE 191
S F ++ SGF++ L + LG+ ++ S V V++ + + +
Sbjct 142 STFGTV-SGFIFGVWKGWLLYASATVLGSICSFIASRTVLSKFVHRLVERDKRFAALALT 200
Query 192 RHREHLINYIIFLRITPFLPNWFINIT-SPVINVPLKVFFIGTFLGVAPPSFVAIKAGTT 250
+ L + +R+ P LP N S V ++ + T + ++P V G+
Sbjct 201 LKYDGL-KLLCMIRLCP-LPYSICNGAISTFPTVQPLMYGLATAI-ISPKLLVPAFIGSR 257
Query 251 LYQLTTAGEAVSWNSIFILMILAVLSILPAIF 282
+ L GE +S S I + ++SI IF
Sbjct 258 IRILNEKGEEMSLGSKLINIFSIIVSIAAGIF 289
>sp|A7EFY0|TVP38_SCLS1 Golgi apparatus membrane protein tvp38
OS=Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)
OX=665079 GN=tvp38 PE=3 SV=1
Length=393
Score = 37.4 bits (85), Expect = 0.14, Method: Composition-based stats.
Identities = 23/118 (19%), Positives = 49/118 (42%), Gaps = 4/118 (3%)
Query 138 LSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHL 197
++GF+Y P +V + G++ ++ S + V++ + + + + +
Sbjct 154 IAGFVYGVPKGWAIVATSTVAGSTCSFLASRTILSTYVHRLVGKDKRFEALALTLKHDG- 212
Query 198 INYIIFLRITPFLPNWFINIT-SPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQL 254
I + +R+ P LP N + V + + T L V P F+ + G+ L L
Sbjct 213 IKILCMIRLCP-LPYSLSNAAVATFPTVHPLNYALATAL-VTPKLFIHVFIGSRLGSL 268
>sp|Q55705|Y232_SYNY3 Uncharacterized membrane protein slr0232
OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
OX=1111708 GN=slr0232 PE=3 SV=1
Length=218
Score = 36.2 bits (82), Expect = 0.20, Method: Composition-based stats.
Identities = 37/214 (17%), Positives = 76/214 (36%), Gaps = 28/214 (13%)
Query 95 AKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYP---FPLALFL 151
+ L ++ +Y Y V IPG +++L GFL L
Sbjct 8 LETLQELARQYG---YGAVFFGIALENA---GIPIPGET-ITLLGGFLAGSGDLSYGGVL 60
Query 152 VCLCSG--LGASFCYMLSYLVGRPVVYKYLT------EKAVKWSQQVERHREHLINYIIF 203
+ +G LG S Y + G P++ + EK + + ++ + + F
Sbjct 61 IAAIAGAVLGDSCGYWVGRWGGWPLLTRAAQLFNIPQEKLDQARHKFSQNGAAAVFFGRF 120
Query 204 LRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSW 263
+ + F + ++ +P F + G + + + + L ++ T + ++W
Sbjct 121 VTLLRI----FAGPMAGIVRMPYGKFLLYNIGGASVWAAITVSLAYFLGRVVTIEQIIAW 176
Query 264 NSIFILMILAVLSILPAI------FQKKLKQKFE 291
+ F LA + + I QK+ Q E
Sbjct 177 TTQFSWFALAAVVGMVGIYFVFHFLQKRFDQTIE 210
>sp|A8NX72|TVP38_COPC7 Golgi apparatus membrane protein TVP38
OS=Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618
/ FGSC 9003) OX=240176 GN=TVP38 PE=3 SV=1
Length=294
Score = 36.2 bits (82), Expect = 0.24, Method: Composition-based stats.
Identities = 31/137 (23%), Positives = 55/137 (40%), Gaps = 18/137 (13%)
Query 131 GSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQV 190
G L L GF Y ++ S LG++ ++ V+ TEK WS Q
Sbjct 94 GHTTLVTLCGFAYGMK-GFYIAFAGSILGSALVFV--------VLRFLFTEKIRSWSAQN 144
Query 191 ERH-------REHLINYIIFLRITPFLPNWFIN-ITSPVINVPLKVFFIGTFLGVAPPSF 242
E+ R + I+ +R++PF P + N + + + V L F T + P
Sbjct 145 EKWQALEAVVRSKGLPLIVLIRVSPFPPWVYANSLFASIEPVKLWQFVAAT-CFITPKLL 203
Query 243 VAIKAGTTLYQLTTAGE 259
+ + G+ + L+ +
Sbjct 204 LYVFMGSKMAALSDGDQ 220
>sp|A2Q9P2|TVP38_ASPNC Golgi apparatus membrane protein tvp38
OS=Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC
A1513) OX=425011 GN=tvp38 PE=3 SV=2
Length=415
Score = 35.8 bits (81), Expect = 0.40, Method: Composition-based stats.
Identities = 11/78 (14%), Positives = 33/78 (42%), Gaps = 2/78 (3%)
Query 132 SIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVE 191
S F ++ +G+++ L + LG++ +++S + V++ + + +
Sbjct 142 STFGTM-AGYIFGIWKGWLLYASATVLGSTCSFIVSRTILSKFVHRLMERDKRFAALSLT 200
Query 192 RHREHLINYIIFLRITPF 209
+ L + +R+ P
Sbjct 201 LKYDGL-KLLCMIRLCPL 217
>sp|O34908|YKOX_BACSU Uncharacterized membrane protein YkoX OS=Bacillus
subtilis (strain 168) OX=224308 GN=ykoX PE=3 SV=1
Length=221
Score = 35.0 bits (79), Expect = 0.47, Method: Composition-based stats.
Identities = 35/167 (21%), Positives = 67/167 (40%), Gaps = 11/167 (7%)
Query 94 DAKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVC 153
+ A+ +++ + + F ++YF ++ L IP + L + ++ + L V
Sbjct 9 ELVAIEELVMSWIEAFKS---LSYFGIFLALSIEFIPAEVVLPLAGYWVSKGDMTLAGVV 65
Query 154 LCSGLGAS----FCYMLSYLVGRPVVY---KYLTEKAVKWSQQVERHREHLINYIIFLRI 206
L LG Y + GRP + KYL K + ++H R
Sbjct 66 LAGSLGGVAGPLTLYWIGRYGGRPFLERFGKYLFIKPEALDKSDNFFKKHGGFVAFSGRF 125
Query 207 TPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQ 253
P + I+I + + + VF + TF+ + P +FV + G L +
Sbjct 126 LPGIRT-LISIPCGIAKMNVWVFSLYTFIAMLPITFVYVYLGVKLGE 171
>sp|Q0CT01|TVP38_ASPTN Golgi apparatus membrane protein tvp38
OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663
GN=tvp38 PE=3 SV=1
Length=418
Score = 35.4 bits (80), Expect = 0.60, Method: Composition-based stats.
Identities = 16/101 (16%), Positives = 43/101 (43%), Gaps = 6/101 (6%)
Query 109 FYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSY 168
F+V L +F ++ L + S F ++ +G+++ L + LG++ +++S
Sbjct 124 FFVLWLCVFFVSFPPLVGW----STFGTV-AGYIFGVWKGWLLYASATVLGSTASFIVSR 178
Query 169 LVGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRITPF 209
+ V++ + + + + L + +R+ P
Sbjct 179 TILSKFVHRLMERDKRFAALALTLKYDGL-KLLCMIRLCPL 218
>sp|P0ABP6|DEDA_ECOLI Protein DedA OS=Escherichia coli (strain
K12) OX=83333 GN=dedA PE=1 SV=1
Length=219
Score = 34.7 bits (78), Expect = 0.65, Method: Composition-based stats.
Identities = 31/195 (16%), Positives = 75/195 (38%), Gaps = 15/195 (8%)
Query 98 LGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFL-------YPFPLALF 150
L +++++Y Y + + F + T +PG L ++G L + +
Sbjct 18 LAELVAEYGVWVYAILFLILFCETGLVVTPFLPGDSLL-FVAGALASLETNDLNVHMMVV 76
Query 151 LVCLCSGLGASFCYMLSYLVGRPVVYKYLTE--KAVKWSQQVERHREHLINYIIFLRITP 208
L+ + + +G + Y + L G + ++ + + + + +H II R P
Sbjct 77 LMLIAAIVGDAVNYTIGRLFGEKLFSNPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVP 136
Query 209 FLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFI 268
+ F + + ++ + F +G + AG + + N +
Sbjct 137 IVRT-FAPFVAGMGHMSYRHFAAYNVIGALLWVLLFTYAGYFFGTIPMVQD----NLKLL 191
Query 269 LMILAVLSILPAIFQ 283
++ + V+SILP + +
Sbjct 192 IVGIIVVSILPGVIE 206
>sp|P0ABP7|DEDA_ECO57 Protein DedA OS=Escherichia coli O157:H7
OX=83334 GN=dedA PE=3 SV=1
Length=219
Score = 34.7 bits (78), Expect = 0.65, Method: Composition-based stats.
Identities = 31/195 (16%), Positives = 75/195 (38%), Gaps = 15/195 (8%)
Query 98 LGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFL-------YPFPLALF 150
L +++++Y Y + + F + T +PG L ++G L + +
Sbjct 18 LAELVAEYGVWVYAILFLILFCETGLVVTPFLPGDSLL-FVAGALASLETNDLNVHMMVV 76
Query 151 LVCLCSGLGASFCYMLSYLVGRPVVYKYLTE--KAVKWSQQVERHREHLINYIIFLRITP 208
L+ + + +G + Y + L G + ++ + + + + +H II R P
Sbjct 77 LMLIAAIVGDAVNYTIGRLFGEKLFSNPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVP 136
Query 209 FLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFI 268
+ F + + ++ + F +G + AG + + N +
Sbjct 137 IVRT-FAPFVAGMGHMSYRHFAAYNVIGALLWVLLFTYAGYFFGTIPMVQD----NLKLL 191
Query 269 LMILAVLSILPAIFQ 283
++ + V+SILP + +
Sbjct 192 IVGIIVVSILPGVIE 206
>sp|Q57654|Y201_METJA Uncharacterized protein MJ0201 OS=Methanocaldococcus
jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1
/ JCM 10045 / NBRC 100440) OX=243232 GN=MJ0201 PE=4 SV=1
Length=160
Score = 33.1 bits (74), Expect = 1.6, Method: Composition-based stats.
Identities = 37/140 (26%), Positives = 54/140 (39%), Gaps = 19/140 (14%)
Query 107 DTFYVQVLVAYFATYIFLQTFA------IPGSIFLSILSGFLYPFPLALFLVCLCSGL-- 158
F + ++ Y IFL F+ P IF I++G L L LV L S +
Sbjct 8 KEFLLNLIKDYGYFGIFLVGFSEPIFQPFPTEIF--IIAGILLG--LDWKLVWLISTIAC 63
Query 159 --GASFCYMLSYLVGRPVVYKYL-TEKAVKWSQQVERHREHLINYIIFLRITPFLPNWFI 215
GA Y L+ G ++ K EK K S +++ I +I TP P I
Sbjct 64 NFGAVVTYYLAKKYGEKLMLKLFDEEKIKKGSHYLKKWG---ILGVIIASFTPI-PFEVI 119
Query 216 NITSPVINVPLKVFFIGTFL 235
+P + + I FL
Sbjct 120 CWVCGSFEMPFERYMIAVFL 139
>sp|Q48630|APL_LACLM Alkaline phosphatase-like protein OS=Lactococcus
lactis subsp. cremoris (strain MG1363) OX=416870 GN=apl
PE=3 SV=2
Length=214
Score = 33.5 bits (75), Expect = 1.6, Method: Composition-based stats.
Identities = 33/174 (19%), Positives = 67/174 (39%), Gaps = 21/174 (12%)
Query 129 IPGSIFLSILSGFL-----YPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEK- 182
IP + L+ GF+ + + S LGA Y + L+ + + ++ +
Sbjct 30 IPSEVILTF-GGFMTTYSELGIIGMIIAATIGSVLGALILYFVGRLLSVERLERLVSGRL 88
Query 183 ---AVKWSQQVERHREHLIN----YIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFL 235
+ + + + + I F R P + + I++ + + L F I T L
Sbjct 89 GKVLRLKPEDITKAEKWFLKRGYATIFFCRFIPLIRS-LISVPAGSAKMKLPSFLILTTL 147
Query 236 GVAPPSFVAIKAGTTLYQ----LTTAGEAVSWNSIFILMILAVLSILPAIFQKK 285
G + V + G L + ++ S + IL ++ +L +L +F KK
Sbjct 148 GTLIWNIVLVSLGAALGDNWEMIAGILDSYSSVVVAILGVIFILGLL--LFVKK 199
>sp|A7MB75|TM231_BOVIN Transmembrane protein 231 OS=Bos taurus
OX=9913 GN=TMEM231 PE=2 SV=1
Length=316
Score = 33.5 bits (75), Expect = 2.2, Method: Composition-based stats.
Identities = 12/50 (24%), Positives = 23/50 (46%), Gaps = 0/50 (0%)
Query 40 KEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVP 89
K S+ E + R +L+ L + FL + FP + + +++VP
Sbjct 51 KRSSYEEQPTVRFQHQVLLVALLGSEPGGFLAWSTFPAFNRLQEGHLRVP 100
>sp|P57239|Y139_BUCAI Uncharacterized membrane protein BU139 OS=Buchnera
aphidicola subsp. Acyrthosiphon pisum (strain APS)
OX=107806 GN=BU139 PE=3 SV=1
Length=256
Score = 33.1 bits (74), Expect = 2.2, Method: Composition-based stats.
Identities = 30/163 (18%), Positives = 59/163 (36%), Gaps = 17/163 (10%)
Query 115 VAYFATYIFLQTFAI-----PGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYL 169
+ FL++ A+ PG I ++ L F+ L+ + + G +SY
Sbjct 17 LLVVGIVSFLESLALVGLLLPGIILMTTLGTFIGDGKLSFYPAWISGTTGCLLGDWISYY 76
Query 170 VGRPVVYKYLTEKAVKWSQQVERHREHLINYIIFLRIT------PFLPNWFINITSPVIN 223
+G +K +Q++ + ++ L I P P I + S ++
Sbjct 77 IGLYFKNWLYNFNFLKKNQKLLDKTKSFLDKHSMLTIILGRFIGPTRP--LIPMVSGMLK 134
Query 224 VPLKVFFIGTFLGVA--PPSFVA--IKAGTTLYQLTTAGEAVS 262
+PLK F + +G PP + I G + ++
Sbjct 135 LPLKKFVFPSIIGCILWPPVYFFPGIVTGIAIKIPESSQSYYF 177
>sp|P0CP22|CCR4_CRYNJ CCR4-Not complex 3'-5'-exoribonuclease subunit
Ccr4 OS=Cryptococcus neoformans var. neoformans serotype
D (strain JEC21 / ATCC MYA-565) OX=214684 GN=CCR4 PE=3 SV=1
Length=744
Score = 33.5 bits (75), Expect = 2.9, Method: Composition-based stats.
Identities = 14/82 (17%), Positives = 22/82 (27%), Gaps = 0/82 (0%)
Query 17 TTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFP 76
+ P A A P Q E E + + L L I L + +
Sbjct 199 SDPSLTPAQNPAEPATPAPVAGQTESKDEEKPNEPWTGLDLGGIRLKRLSTALFSFTHVT 258
Query 77 QLSEEERVNMKVPRDMDDAKAL 98
L +P + + L
Sbjct 259 SLYINHNALTSIPSAISSLRQL 280
>sp|P0CP23|CCR4_CRYNB CCR4-Not complex 3'-5'-exoribonuclease subunit
Ccr4 OS=Cryptococcus neoformans var. neoformans serotype
D (strain B-3501A) OX=283643 GN=CCR4 PE=3 SV=1
Length=744
Score = 33.5 bits (75), Expect = 2.9, Method: Composition-based stats.
Identities = 14/82 (17%), Positives = 22/82 (27%), Gaps = 0/82 (0%)
Query 17 TTPVGDGAAGTRGLAAPGSRDHQKEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFP 76
+ P A A P Q E E + + L L I L + +
Sbjct 199 SDPSLTPAQNPAEPATPAPVAGQTESKDEEKPNEPWTGLDLGGIRLKRLSTALFSFTHVT 258
Query 77 QLSEEERVNMKVPRDMDDAKAL 98
L +P + + L
Sbjct 259 SLYINHNALTSIPSAISSLRQL 280
>sp|Q9CHL6|APL_LACLA Alkaline phosphatase-like protein OS=Lactococcus
lactis subsp. lactis (strain IL1403) OX=272623 GN=apl
PE=3 SV=1
Length=214
Score = 32.7 bits (73), Expect = 3.1, Method: Composition-based stats.
Identities = 27/138 (20%), Positives = 50/138 (36%), Gaps = 15/138 (11%)
Query 129 IPGSIFLSILSGFL-----YPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEK- 182
IP + L+ GF+ + + S LGA Y + L+ + K ++ +
Sbjct 30 IPSEVILTF-GGFMTTYSELGIIGMIIAATIGSVLGALILYFVGRLLSVERLEKLVSGRL 88
Query 183 ---AVKWSQQVERHREHLIN----YIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFL 235
+ + + + + I F R P + + I+I + + L F I T L
Sbjct 89 GKVLRLKPEDITKAEKWFLKRGYATIFFCRFIPLIRS-LISIPAGSAKMKLPSFLILTTL 147
Query 236 GVAPPSFVAIKAGTTLYQ 253
G + V + G L
Sbjct 148 GTLIWNIVLVCLGAALGD 165
>sp|Q3U284|TM231_MOUSE Transmembrane protein 231 OS=Mus musculus
OX=10090 GN=Tmem231 PE=1 SV=1
Length=315
Score = 32.7 bits (73), Expect = 3.9, Method: Composition-based stats.
Identities = 12/50 (24%), Positives = 22/50 (44%), Gaps = 0/50 (0%)
Query 40 KEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVP 89
K S+ E + R +L+ L FL + FP + + +++VP
Sbjct 51 KRSSYEEQPNVRFQHQVLLVALLGPEPEAFLAWSTFPTFNRLQGAHLRVP 100
>sp|P30149|YABI_ECOLI Inner membrane protein YabI OS=Escherichia
coli (strain K12) OX=83333 GN=yabI PE=1 SV=2
Length=254
Score = 32.3 bits (72), Expect = 4.0, Method: Composition-based stats.
Identities = 22/150 (15%), Positives = 55/150 (37%), Gaps = 8/150 (5%)
Query 95 AKALGKVLSKYKDTFYVQVLVAYFATYIFLQTFAIPGSIFLSILSGFL----YPFPLALF 150
L +++ + V++ F + L +PG++ ++ L + F A
Sbjct 2 QALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAGLGALIGSGELSFWHAWL 61
Query 151 LVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERH-REHLINYIIFLRIT-P 208
+ +G + L + +P+ +K + E +H + I+ R P
Sbjct 62 AGIIGCLMGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTEHALHQHSMFTILVGRFVGP 121
Query 209 FLPNWFINITSPVINVPLKVFFIGTFLGVA 238
P + + + ++++P+ F +G
Sbjct 122 TRP--LVPMVAGMLDLPVAKFITPNIIGCL 149
>sp|Q759P7|TVP38_EREGS Golgi apparatus membrane protein TVP38
OS=Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC
9923 / NRRL Y-1056) OX=284811 GN=TVP38 PE=3 SV=1
Length=307
Score = 32.3 bits (72), Expect = 4.5, Method: Composition-based stats.
Identities = 36/169 (21%), Positives = 73/169 (43%), Gaps = 23/169 (14%)
Query 143 YPFPLALFLVCLCSGL--GASFCYMLSYLVGRPV-----------VYKYLTEKAVKWSQQ 189
+P + ++C +GL G SF L +G + V++ E+ ++ + +
Sbjct 125 FPPLIGFSMLCTSAGLVYGVSFKGWLIISLGTVLGSIAAFSVFKTVFRSYAERLIRLNDK 184
Query 190 VER----HREHLINYII-FLRITPFLPNWFINIT-SPVINVPLKVFFIGTFLGVAPPSFV 243
E ++H +II LR+ PF P N + V + ++ F I L P F+
Sbjct 185 FEALASILQDHNSYWIIALLRLCPF-PYSLTNGAIAGVYGISIRNFSIAQVL-TTPKLFM 242
Query 244 AIKAGTTLYQL--TTAGEAVSWNSIFILMILAVLSILPAIFQKKLKQKF 290
+ G+ L L +++ ++ + IL + L+ +I K K+++
Sbjct 243 YLFIGSRLKNLGESSSTATKLFDILSILFAIIALTATASILYYKTKERY 291
>sp|Q2FZT9|UNDPT_STAA8 Putative undecaprenyl phosphate transporter
SAOUHSC_00901 OS=Staphylococcus aureus (strain NCTC 8325
/ PS 47) OX=93061 GN=SAOUHSC_00901 PE=3 SV=1
Length=191
Score = 32.0 bits (71), Expect = 4.6, Method: Composition-based stats.
Identities = 31/148 (21%), Positives = 55/148 (37%), Gaps = 9/148 (6%)
Query 143 YPFPLALFLVCLCSGLGASFCYMLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLINYII 202
Y L + + L G Y++ + + + ++ R+ LI I
Sbjct 47 YGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFI 106
Query 203 FLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVS 262
L PF PN IN + + ++ K +FI + + G + + T
Sbjct 107 LL-CFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILT----HP 161
Query 263 WNSIFILMILAVLSILPAIFQKKLKQKF 290
I +L++L V I+ KKL+Q F
Sbjct 162 LRGILMLVVLVVFWIV----GKKLEQHF 185
>sp|Q755Y0|AKR1_EREGS Palmitoyltransferase AKR1 OS=Eremothecium
gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL
Y-1056) OX=284811 GN=AKR1 PE=3 SV=1
Length=724
Score = 32.3 bits (72), Expect = 5.2, Method: Composition-based stats.
Identities = 34/154 (22%), Positives = 61/154 (40%), Gaps = 16/154 (10%)
Query 86 MKVPRDMDDAKALGKVLSKYKDTFYVQVLVAYFA--TYIFLQTFAIPGSIFLSILSGFLY 143
+ + ++M+ KAL L + + YF + + TF P I ILS F Y
Sbjct 262 LMIAQEMNTQKALQNALYECGFNKDGFAIRKYFKNPMHAKMVTFFTPWLILGLILSFFAY 321
Query 144 PFPLALFLVCLCSGLGASFCY----MLSYLVGRPVVYKYLTEKAVKWSQQVERHREHLIN 199
L L CL + L A + S+++ + +V A S I
Sbjct 322 FSILLAILGCLLTVLAAGYGLYNFVFPSFILMKRIVIFKTPLLAGILS--------GTIF 373
Query 200 YIIFLRITPFLPNWFINITSPVINVPLKVFFIGT 233
+++++ + LP F + P++N+ + F G
Sbjct 374 WLLYVWLFKMLPATFDD--EPILNLTVFALFAGV 405
>sp|Q5RBT8|TM231_PONAB Transmembrane protein 231 OS=Pongo abelii
OX=9601 GN=TMEM231 PE=2 SV=1
Length=316
Score = 32.0 bits (71), Expect = 5.6, Method: Composition-based stats.
Identities = 12/50 (24%), Positives = 21/50 (42%), Gaps = 0/50 (0%)
Query 40 KEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVP 89
K S+ E + R +L+ L FL + FP + + ++VP
Sbjct 51 KRSSYEEQPTVRFQHQVLLVALLGPESGGFLAWSTFPAFNRLQGDRLRVP 100
>sp|Q89AV4|Y130_BUCBP Uncharacterized membrane protein bbp_130
OS=Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
OX=224915 GN=bbp_130 PE=3 SV=1
Length=257
Score = 32.0 bits (71), Expect = 5.8, Method: Composition-based stats.
Identities = 34/175 (19%), Positives = 60/175 (34%), Gaps = 8/175 (5%)
Query 110 YVQVLVAYFATYIFLQTFAIPGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYL 169
VL+ F + L +PG + +SIL + L+ + + +G +SY
Sbjct 17 LFMVLIVTFLESLALVGLFLPGIVLMSILGTLIGNGTLSFYPAWIVGIIGCMCGDWISYY 76
Query 170 VGRPVV-----YKYLTEKAVKWSQQVERHREHLINYIIFLRIT-PFLPNWFINITSPVIN 223
G L V + + I I+ R P P + + ++N
Sbjct 77 CGFKFKKCITNLHLLKNNNVVLDKITNTLTNYPITTILLGRFIGPTRP--LVPMVCGMLN 134
Query 224 VPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTAGEAVSWNSIFILMILAVLSIL 278
+ LK F I LG + G + S N+ F + LA + ++
Sbjct 135 ISLKTFIIPNILGCILWPPIYFLPGIFTGIAISNTTNYSENTYFKIQFLAAILLI 189
>sp|Q8KA02|Y132_BUCAP Uncharacterized membrane protein BUsg_132
OS=Buchnera aphidicola subsp. Schizaphis graminum (strain
Sg) OX=198804 GN=BUsg_132 PE=3 SV=1
Length=252
Score = 31.6 bits (70), Expect = 7.1, Method: Composition-based stats.
Identities = 28/135 (21%), Positives = 54/135 (40%), Gaps = 13/135 (10%)
Query 115 VAYFATYIFLQTFAI-----PGSIFLSILSGFLYPFPLALFLVCLCSGLGASFCYMLSYL 169
+ FL++ A+ PG +F++ L F+ L + + +G SY
Sbjct 17 ILIVGIVSFLESLALVGLLLPGIVFMATLGTFIGNGKLPFYPSWIAGIIGCLLGDWCSYF 76
Query 170 VGRPVVYKYLTEKAVKWSQQVERHREHLIN-----YIIFLRIT-PFLPNWFINITSPVIN 223
+G + K +K + + + L++ I+ R P P I + S ++
Sbjct 77 IGLYFKNWLYSLKFLKKNCHLLDKTKSLLHKHSMITILVGRFIGPTRP--LIPMVSGMLK 134
Query 224 VPLKVFFIGTFLGVA 238
+PLK F + + LG
Sbjct 135 LPLKKFILPSLLGCI 149
>sp|Q5FVM1|TM231_RAT Transmembrane protein 231 OS=Rattus norvegicus
OX=10116 GN=Tmem231 PE=2 SV=2
Length=315
Score = 31.6 bits (70), Expect = 7.5, Method: Composition-based stats.
Identities = 11/50 (22%), Positives = 23/50 (46%), Gaps = 0/50 (0%)
Query 40 KEKSWVEAGSARMSLLILVSIFLSAAFVMFLVYKNFPQLSEEERVNMKVP 89
K ++ E + R +L+ L FL + +P + + V+++VP
Sbjct 51 KRSNYEEQPNVRFQHQVLLVALLGPEPGAFLAWSTYPTFNRLQGVHLRVP 100
>sp|B4QL99|MAEL_DROSI Protein maelstrom OS=Drosophila simulans
OX=7240 GN=mael PE=3 SV=1
Length=394
Score = 31.6 bits (70), Expect = 8.1, Method: Composition-based stats.
Identities = 10/50 (20%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
Query 209 FLPNWFINITSPVI----NVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQL 254
F N F T+ + ++ + + + T +G+ P + + G+TL +
Sbjct 286 FFKNDFFEFTAGIACQISSINTRDYHVATLIGLLPAQTINVYLGSTLRSM 335
>sp|B4IB36|MAEL_DROSE Protein maelstrom OS=Drosophila sechellia
OX=7238 GN=mael PE=3 SV=1
Length=394
Score = 31.6 bits (70), Expect = 8.1, Method: Composition-based stats.
Identities = 10/50 (20%), Positives = 23/50 (46%), Gaps = 4/50 (8%)
Query 209 FLPNWFINITSPVI----NVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQL 254
F N F T+ + ++ + + + T +G+ P + + G+TL +
Sbjct 286 FFKNDFFEFTAGIACQISSINTRDYHVATLIGLLPAQTINVYLGSTLRSM 335
>sp|P96665|YDEH_BACSU Uncharacterized membrane protein YdeH OS=Bacillus
subtilis (strain 168) OX=224308 GN=ydeH PE=4 SV=1
Length=148
Score = 30.8 bits (68), Expect = 9.4, Method: Composition-based stats.
Identities = 22/76 (29%), Positives = 40/76 (53%), Gaps = 1/76 (1%)
Query 198 INYIIFLRITPFLPNWFINITSPVINVPLKVFFIGTFLGVAPPSFVAIKAGTTLYQLTTA 257
I ++FL I P + ++F N+ +I+ + F + TFLG+ P F+ I G ++ A
Sbjct 68 IGIVVFLLIPPLVMSFFGNLVVRIISGVYQCFIVFTFLGLIPIGFL-IPNGFLTILVSIA 126
Query 258 GEAVSWNSIFILMILA 273
G VS S+ + + +
Sbjct 127 GTLVSIASVAVTLCIG 142
Lambda K H a alpha
0.317 0.133 0.349 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0406 0.140 1.90 42.6 43.6
Effective search space used: 24499859112
Database: uniprot_sprot.fasta
Posted date: Jun 30, 2025 8:32 PM
Number of letters in database: 207,922,125
Number of sequences in database: 573,661
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40