Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -2 -3 -3 -1 -1 -3 -3 -2 3 2 -2 5 0 -3 -2 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 41 0 0 59 0 0 0 0 0 0 0 0.30 0.00 2 K -1 1 0 0 -3 5 2 -2 0 -3 -2 3 -1 -3 -1 0 -1 -2 -2 -2 0 0 0 0 0 71 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0.54 0.00 3 K -1 1 -1 0 -3 1 3 -2 -1 -1 0 2 3 -2 -2 -1 -1 -3 -2 -1 0 0 0 0 0 0 41 0 0 0 0 29 30 0 0 0 0 0 0 0 0.27 0.00 4 M -1 -2 -2 -3 -2 0 -2 -3 -2 1 2 -2 6 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.37 0.01 5 S 3 -1 0 -1 -1 -1 -1 0 -2 -1 -2 -1 -1 -2 -1 2 3 -3 -2 -1 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29 30 0 0 0 0.31 0.00 6 R -1 5 0 -1 -4 1 0 -2 0 -3 -2 4 -1 -3 -2 -1 -1 -3 -2 -3 0 59 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0.58 0.00 7 N -1 0 3 4 -3 0 1 -1 0 -3 -3 2 -2 -3 -2 0 -1 -4 -3 -3 0 0 29 41 0 0 0 0 0 0 0 30 0 0 0 0 0 0 0 0 0.49 0.00 8 V 0 -3 -3 -3 -1 -2 -3 -3 -3 3 1 -2 1 -1 -3 -2 0 -3 -1 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0.36 0.00 9 L -2 -1 4 -1 -2 -1 -2 -2 -1 0 3 -1 1 -1 -3 -1 -1 -3 -2 0 0 0 41 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 0.23 0.00 10 L -2 -3 -4 -4 -1 -3 -3 -4 -3 3 3 -3 2 0 -3 -3 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 41 59 0 0 0 0 0 0 0 0 0 0.38 0.00 11 Q -1 0 3 -1 -2 3 0 -2 0 0 2 0 1 -1 -2 -1 -1 -2 -2 -1 0 0 30 0 0 29 0 0 0 0 41 0 0 0 0 0 0 0 0 0 0.19 0.00 12 M -2 -2 -3 -4 -2 -1 -3 -3 -2 1 2 -2 5 4 -3 -2 -1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 59 41 0 0 0 0 0 0 0.35 0.00 13 E -1 -1 0 4 -4 1 4 -2 -1 -3 -3 0 -3 -4 -1 0 -1 -4 -3 -3 0 0 0 41 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0.68 0.00 14 E -1 -1 -1 1 -3 1 4 -3 -1 -1 1 0 0 -2 -2 -1 -1 -3 -2 -1 0 0 0 0 0 0 70 0 0 0 30 0 0 0 0 0 0 0 0 0 0.37 0.00 15 E -1 -1 -1 0 -3 1 4 -3 -1 0 2 0 0 -1 -2 -1 -1 -2 -2 -1 0 0 0 0 0 0 59 0 0 0 41 0 0 0 0 0 0 0 0 0 0.30 0.00 16 E -1 0 0 2 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.74 0.01 17 D -1 1 1 5 -4 0 1 -2 -1 -3 -3 3 -2 -4 -1 0 -1 -4 -3 -3 0 0 0 59 0 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0.56 0.00 18 D -2 -2 1 6 -4 0 2 -1 -1 -3 -4 -1 -3 -4 -2 0 -1 -5 -3 -3 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.94 0.01 19 D -2 -2 1 6 -4 0 2 -1 -1 -3 -4 -1 -3 -4 -2 0 -1 -5 -3 -3 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.94 0.01 20 D -2 -1 1 5 -4 1 3 -2 -1 -3 -4 0 -3 -4 -1 0 -1 -4 -3 -3 0 0 0 70 0 0 30 0 0 0 0 0 0 0 0 0 0 0 0 0 0.76 0.00 21 G 0 -2 1 3 -2 -1 0 3 -1 -3 -3 -1 -2 -3 -1 2 0 -3 -3 -3 0 0 0 30 0 0 0 29 0 0 0 0 0 0 0 41 0 0 0 0 0.42 0.00 22 D -1 -2 -1 3 -2 -1 -1 3 -2 0 2 -2 0 -1 -2 -1 -1 -3 -2 -1 0 0 0 29 0 0 0 30 0 0 41 0 0 0 0 0 0 0 0 0 0.22 0.00 23 I -2 -3 -4 -4 -1 -3 -3 -4 -3 4 3 -3 2 0 -3 -3 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 59 41 0 0 0 0 0 0 0 0 0 0.36 0.00 24 V -1 -1 -1 -2 -2 -1 -1 -3 5 1 0 -2 0 -1 -2 -1 -1 -3 0 3 0 0 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0 0 59 0.27 0.00 25 L -1 -2 -3 -3 -2 -2 -2 -3 -3 0 3 -2 1 -1 5 -2 -1 -2 -2 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 41 0 0 0 0 0 0.66 0.00 26 E 0 -1 0 1 -3 1 4 4 -1 -4 -3 0 -2 -3 -2 0 -1 -3 -3 -3 0 0 0 0 0 0 59 41 0 0 0 0 0 0 0 0 0 0 0 0 0.54 0.00 27 N -2 -1 6 1 -3 0 0 0 1 -4 -4 0 -2 -3 -2 1 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.74 0.01 28 L -2 -3 -4 -4 -2 -3 -3 -4 -2 1 3 -3 2 4 -3 -3 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 70 0 0 30 0 0 0 0 0 0 0.40 0.00 29 G 0 -2 0 3 -2 -1 0 3 -2 -2 -3 -1 -2 -3 -2 1 3 -3 -3 -2 0 0 0 30 0 0 0 29 0 0 0 0 0 0 0 0 41 0 0 0 0.37 0.00 30 Q 0 0 0 0 -2 4 1 -1 0 -3 -2 1 -1 -3 -1 2 0 -2 -2 -2 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0.43 0.00 31 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.48 0.01 32 I -1 -1 -2 -1 -1 -1 -1 -2 -2 3 1 -1 1 0 -1 -1 0 -1 -1 2 3 2 2 2 1 2 3 3 1 61 4 2 1 2 2 3 2 1 1 3 0.10 0.00 33 V 0 -2 -2 -2 -1 -2 -2 -2 -3 3 1 -2 0 -1 -2 1 0 -3 -2 3 0 0 0 0 0 0 0 0 0 38 0 0 0 0 0 25 0 0 0 37 0.20 0.01 34 P -1 -1 -1 1 -4 1 4 -2 -1 -3 -3 0 -2 -4 5 0 -1 -3 -3 -3 0 0 0 0 0 0 63 0 0 0 0 0 0 0 37 0 0 0 0 0 0.87 0.01 35 D -2 -1 3 5 -3 0 1 -1 -1 -3 -3 -1 -3 -3 -2 0 1 -4 -3 -3 0 0 20 66 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0.65 0.02 36 L -1 -2 -3 -3 -1 -2 -3 -3 -3 2 3 -2 1 2 -3 -1 1 -1 0 1 0 0 0 0 0 0 0 0 0 15 50 0 0 15 0 0 20 0 0 0 0.25 0.01 37 G 0 -2 0 -1 -2 -2 -2 5 -2 -4 -4 -1 -3 -3 -2 1 -1 -3 -3 -3 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 20 0 0 0 0 0.83 0.02 38 S 0 2 0 -1 -2 0 -1 -1 0 -2 -2 0 -1 0 -2 3 0 0 4 -2 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 49 0 0 31 0 0.30 0.02 39 L -1 -1 -3 -3 -2 -1 -2 -3 -3 1 4 1 2 0 -3 -2 -1 -2 -1 0 0 0 0 0 0 0 0 0 0 0 80 20 0 0 0 0 0 0 0 0 0.30 0.02 40 E -1 -1 -1 1 -4 1 5 -2 -1 -3 -3 0 -2 -4 5 0 -1 -3 -3 -3 0 0 0 0 0 0 69 0 0 0 0 0 0 0 31 0 0 0 0 0 0.82 0.02 41 S 2 -1 2 0 -1 0 -1 -1 -1 -2 -2 0 -1 -3 -1 3 2 -3 -2 -1 20 0 15 0 0 0 0 0 0 0 0 0 0 0 0 45 20 0 0 0 0.32 0.01 42 Q 0 0 0 0 -3 3 3 2 0 -3 -3 0 -2 -3 -1 1 0 -3 -2 -3 0 0 0 0 0 29 31 20 0 0 0 0 0 0 0 20 0 0 0 0 0.39 0.01 43 H 0 -1 0 0 -3 2 2 4 3 -4 -3 0 -2 -3 -2 0 -1 -3 -2 -3 0 0 0 0 0 15 20 51 15 0 0 0 0 0 0 0 0 0 0 0 0.50 0.01 44 D -1 -1 1 5 -3 0 2 -2 -1 -2 -3 0 -2 -3 -1 0 2 -4 -3 -2 0 0 0 49 0 0 20 0 0 0 0 0 0 0 0 0 31 0 0 0 0.51 0.02 45 F -1 -2 -2 -3 -1 -2 -2 -3 -2 1 3 -2 1 4 -2 -2 -1 0 1 0 2 1 1 1 0 1 1 1 0 1 52 1 0 30 1 1 1 0 1 1 0.25 0.01 46 R -1 3 0 0 -2 2 1 -1 0 -1 -1 1 -1 -1 0 0 0 -1 -1 -1 4 32 2 3 1 22 3 4 1 3 5 3 1 2 3 4 3 1 2 3 0.19 0.00 47 T 0 0 0 0 -1 0 0 0 -1 -1 -1 0 -1 -1 0 2 3 -1 -1 0 4 3 2 3 1 2 3 4 1 3 5 3 1 2 3 23 32 1 2 3 0.14 0.00 48 P 0 -1 -1 -1 -1 0 0 -1 -1 -1 -1 0 -1 -2 6 0 0 -1 -1 -1 4 3 2 3 1 2 3 4 1 3 5 3 1 2 52 4 3 1 2 3 0.75 0.01 49 E 0 -1 0 0 -2 0 3 -1 -1 -2 -2 0 -1 -2 4 0 2 -2 -1 -1 2 2 1 2 1 1 31 2 1 2 3 2 1 1 21 2 22 0 1 2 0.34 0.01 50 F -2 -2 -3 -2 -2 -2 0 -3 -2 1 2 -2 1 4 -3 -2 -1 -1 1 1 0 0 0 0 0 0 14 0 0 0 28 0 0 40 0 0 0 0 0 18 0.25 0.01 51 E -1 2 3 1 -3 2 3 -2 0 -3 -3 2 -2 -3 -2 0 -1 -3 -2 -3 0 18 28 0 0 14 26 0 0 0 0 14 0 0 0 0 0 0 0 0 0.42 0.01 52 E 0 2 0 0 -3 1 4 -2 -1 -3 -3 2 -2 -3 -1 2 0 -3 -2 -2 0 14 0 0 0 0 44 0 0 0 0 14 0 0 0 28 0 0 0 0 0.41 0.02 53 F -2 2 1 -2 -2 -1 -2 -3 -1 0 2 -1 0 4 -3 -2 -1 -1 1 -1 0 18 14 0 0 0 0 0 0 0 28 0 0 40 0 0 0 0 0 0 0.23 0.01 54 N -1 0 5 1 -2 2 0 -1 0 -3 -3 0 -2 -3 -2 2 0 -3 -2 -3 0 0 58 0 0 14 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0.50 0.02 55 G 0 -1 -1 -1 -2 1 -1 2 3 0 -1 -1 -1 -2 -2 -1 -1 -2 -1 1 1 1 1 1 0 15 1 27 15 1 2 1 0 1 1 1 1 0 1 29 0.13 0.01 56 K 0 1 0 3 -3 0 1 -1 -1 -3 -3 3 -2 -3 -1 2 0 -4 -2 -3 0 0 0 28 0 0 0 0 0 0 0 44 0 0 0 28 0 0 0 0 0.38 0.02 57 P 0 0 -1 -1 -3 0 0 -2 -2 -3 -3 2 -2 -4 6 1 0 -4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 28 0 0 54 18 0 0 0 0 0.97 0.02 58 D -1 -2 3 6 -3 0 1 -1 -1 -3 -4 -1 -3 -4 -2 1 -1 -4 -3 -3 0 0 14 72 0 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0.74 0.03 59 S 2 -2 0 -1 -1 -1 -1 3 -2 -3 -3 -1 -2 -3 -1 3 0 -3 -2 -2 25 0 0 0 0 0 0 28 0 0 0 0 0 0 0 47 0 0 0 0 0.41 0.02 60 L -1 -2 -3 -4 -1 -2 -3 -4 -3 2 4 -3 3 0 -3 -2 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 10 61 0 18 0 0 0 0 0 0 11 0.40 0.03 61 F -2 -2 -2 -3 -3 -2 -2 -3 4 -1 1 -2 0 5 -3 -2 -2 1 5 -1 0 0 0 0 0 0 0 0 17 0 17 0 0 38 0 0 0 0 27 0 0.50 0.03 62 F -3 -3 -4 -4 -3 -4 -4 -4 -2 -1 0 -4 0 7 -4 -3 -3 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.99 0.06 63 N -1 4 1 -1 -3 1 0 -2 4 -3 -3 2 -2 -3 -2 0 0 -3 -1 -3 0 47 9 0 0 0 0 0 17 0 0 17 0 0 0 0 9 0 0 0 0.46 0.03 64 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -1 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.12 0.06 65 G 0 -2 1 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 1 -1 -3 -3 -3 0 0 9 0 0 0 0 83 0 0 0 0 0 0 0 9 0 0 0 0 0.91 0.04 66 Q -1 2 -1 -1 -3 4 1 -2 -1 1 -1 3 -1 -3 -2 -1 -1 -3 -2 -1 0 9 0 0 0 35 0 0 0 20 0 36 0 0 0 0 0 0 0 0 0.32 0.03 67 R -2 6 -1 -2 3 1 0 -3 -1 -3 -3 3 -2 -3 -2 -1 -1 -3 -2 -3 0 76 0 0 9 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0.72 0.06 68 R -1 4 -1 -2 -3 3 0 -2 -1 0 -2 3 -1 -3 -2 -1 -1 -3 -2 -1 0 40 0 0 0 17 0 0 0 14 0 29 0 0 0 0 0 0 0 0 0.42 0.04 69 I 0 -3 -3 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 3 8 0 0 0 0 0 0 0 0 66 0 0 0 0 0 0 0 0 0 26 0.42 0.05 70 D -2 -2 1 7 -4 -1 1 -2 -2 -4 -4 -1 -4 -4 -2 -1 -2 -5 -4 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.21 0.09 71 F -3 -3 -3 -4 -3 -3 -3 -4 0 -1 -1 -3 -1 6 -4 -3 -2 1 6 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 52 0 0 0 0 48 0 0.93 0.07 72 V -1 -3 -4 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 42 0 0 0 0 0 0 0 0 0 58 0.48 0.05 73 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.63 0.06 74 V 1 -2 -2 -3 -1 -2 -2 -2 -3 2 0 -2 0 -2 -2 1 0 -3 -2 4 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 71 0.29 0.05 75 Y -3 -3 -3 -4 -3 -2 -3 -4 1 -2 -2 -3 -2 2 -4 -3 -2 7 7 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22 78 0 1.29 0.09 76 E -1 1 0 0 -3 1 3 -2 5 -1 -2 0 -1 -2 -2 -1 -1 -2 0 0 1 9 1 1 0 1 37 1 27 1 1 1 0 1 1 1 1 0 0 17 0.30 0.03 77 D -1 -1 0 4 -3 1 3 1 -1 -3 -3 1 -2 -3 -1 0 -1 -2 -2 -2 2 1 1 29 0 1 31 15 0 1 2 9 0 1 1 1 1 0 1 1 0.36 0.02 78 E 0 -1 0 4 -3 0 3 -1 2 -3 -3 0 -2 -3 -1 1 -1 -3 -2 -2 8 1 1 39 0 1 28 1 7 1 1 1 0 1 1 9 1 0 0 1 0.42 0.03 79 S 0 1 1 -1 -1 -1 -1 0 -1 0 1 0 0 -1 -1 1 1 -2 -1 0 1 9 9 1 0 1 1 8 0 1 24 7 0 1 1 15 14 0 0 9 0.06 0.01 80 R -1 3 0 -1 -2 2 0 1 -1 -2 -2 3 -1 -2 -1 0 -1 -2 -2 -2 2 29 1 1 0 9 1 15 0 1 2 24 0 1 1 8 1 0 1 1 0.27 0.02 81 K -1 3 1 -1 -3 2 0 -2 -1 -3 -3 4 -2 -3 3 0 -1 -3 -2 -2 1 21 8 0 0 8 1 1 0 0 1 44 0 0 13 1 0 0 0 1 0.44 0.03 82 E -1 0 0 3 -3 2 4 -2 -1 -3 -3 2 -2 -3 -1 0 -1 -3 -2 -3 1 0 0 24 0 8 42 1 0 0 1 14 0 0 0 7 0 0 0 1 0.47 0.03 83 T 0 0 2 0 -2 0 0 0 -1 -1 -2 0 -1 -2 1 1 2 -2 -2 0 9 8 15 1 0 1 8 8 0 1 1 1 0 1 8 9 21 0 1 8 0.15 0.01 84 N 0 -1 4 0 -2 0 1 -1 3 -3 -3 0 -2 -2 3 0 -1 -3 -1 -2 9 1 42 1 0 1 9 1 14 1 1 1 0 1 14 1 1 0 1 1 0.38 0.03 85 K 1 1 -1 -2 -1 0 -1 0 -1 1 0 1 1 -1 -1 0 1 -2 -1 0 16 7 1 1 0 1 1 8 0 14 9 15 7 1 1 1 15 0 1 1 0.05 0.01 86 K -1 2 0 1 -2 1 0 1 -1 -2 -2 3 -1 -2 -1 0 -1 -2 -1 -2 2 9 1 8 1 8 2 16 1 2 3 37 1 1 2 2 2 0 1 2 0.21 0.02 87 G 0 -1 0 3 -2 -1 0 3 -1 -2 -2 -1 -2 -1 -1 0 -1 -1 1 -2 10 2 1 24 1 1 2 36 1 2 3 2 1 1 2 2 2 0 8 2 0.27 0.02 88 T 0 1 0 -1 -1 0 0 -1 2 -1 -1 1 -1 -2 3 0 1 -2 -1 -1 9 10 2 2 1 2 2 3 7 2 3 16 1 1 15 3 16 0 1 2 0.18 0.01 89 N 0 -1 2 0 -1 0 0 2 -1 -2 -2 0 -1 -2 -1 1 2 -2 -2 -1 2 1 16 2 1 1 8 24 1 1 3 2 1 1 2 9 24 0 1 2 0.20 0.01 90 E -1 -1 1 5 -2 0 3 -1 -1 -2 -2 0 -2 -2 -1 0 -1 -2 -2 -2 2 1 1 50 1 1 24 2 1 1 3 2 1 1 2 2 2 0 1 2 0.48 0.03 91 K -1 -1 -1 1 -2 0 0 -2 -1 0 0 1 1 -1 2 0 1 -2 -1 0 2 1 1 14 0 1 1 2 0 8 10 15 8 1 9 2 16 0 1 8 0.09 0.01 92 Q -1 1 0 0 -3 4 2 -2 5 -3 -3 2 -1 -3 -2 -1 -1 -2 -1 -3 1 0 0 0 0 36 14 1 22 0 1 22 0 0 0 1 0 0 0 0 0.46 0.04 93 R 0 3 -1 -1 -2 0 1 -2 0 -1 0 1 -1 -1 -2 -1 0 -1 2 -1 9 28 0 0 0 0 15 1 0 0 14 8 0 0 0 1 9 0 14 0 0.16 0.02 94 R -1 1 -1 2 -3 0 2 1 -1 0 -1 0 -1 1 -2 -1 0 -2 -1 0 0 14 0 13 0 0 24 13 0 7 0 0 0 13 0 0 8 0 0 7 0.12 0.02 95 K -2 3 -1 -2 -3 0 -1 -2 -1 -3 -3 3 -2 -2 2 -1 -2 7 -1 -3 0 29 0 0 0 0 0 0 0 0 0 36 0 0 13 0 0 22 0 0 0.68 0.05 96 R -2 6 -1 -2 -4 0 -1 -3 -1 -2 0 2 -1 -3 -3 -1 -2 -3 -2 -2 0 87 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0.77 0.07 97 Q -1 1 2 2 -4 3 4 -2 0 -4 -3 1 -2 -4 -2 0 -1 -3 -2 -3 0 8 13 13 0 14 43 0 0 0 0 8 0 0 0 0 0 0 0 0 0.51 0.04 98 A 2 -1 -1 -1 -2 0 3 -2 -2 -1 -2 -1 -1 -3 -1 1 3 -3 -2 0 28 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 36 0 0 8 0.28 0.04 99 Y -2 -3 -3 -4 -3 -3 -3 -4 -1 0 1 -3 0 6 -4 -3 -2 1 5 -1 0 0 0 0 0 0 0 0 0 0 13 0 0 59 0 0 0 0 27 0 0.74 0.06 100 E -1 -1 -1 1 -3 1 5 -3 -1 -2 1 0 -1 -2 -2 -1 -1 -3 -2 -2 0 0 0 0 0 0 78 0 0 0 22 0 0 0 0 0 0 0 0 0 0.57 0.07 101 S -1 1 0 1 -3 2 3 1 -1 -3 -3 2 -2 -3 -2 1 0 -3 -2 -2 0 8 0 8 0 8 28 13 0 0 0 13 0 0 0 14 8 0 0 0 0.31 0.02 102 N -2 -1 7 1 -3 0 -1 -1 0 -4 -4 -1 -3 -4 -3 0 -1 -4 -3 -4 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.05 0.09 103 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 5 -3 2 0 -3 -3 -2 -2 -1 1 0 0 0 0 0 0 0 0 0 8 92 0 0 0 0 0 0 0 0 0 0.58 0.06 104 I -2 4 -2 -3 2 0 -1 -3 -1 1 1 1 2 -2 -3 -2 -1 -3 -2 0 0 52 0 0 7 0 0 0 0 14 13 0 13 0 0 0 0 0 0 0 0.33 0.05 105 C 2 -1 -2 -1 4 0 2 -1 -2 -1 -1 1 -1 -2 -2 0 -1 -3 -2 0 36 0 0 0 14 0 20 0 0 0 7 16 0 0 0 0 0 0 0 7 0.19 0.03 106 H 3 -1 -1 -1 -2 0 2 -1 3 -2 -2 -1 -1 -3 -1 1 1 -3 -1 -1 49 0 0 0 0 0 22 0 14 0 0 0 0 0 0 0 16 0 0 0 0.29 0.04 107 G 0 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.26 0.08 108 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 5 -3 2 0 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.63 0.06 109 Q -1 0 -1 1 2 3 3 -2 -1 -2 -2 2 2 -3 -2 -1 -1 -3 -2 -2 0 0 0 8 8 22 34 0 0 0 0 14 13 0 0 0 0 0 0 0 0.35 0.04 110 L -2 -3 -4 -4 -2 -2 -3 -4 -3 2 4 -3 3 0 -3 -3 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 14 70 0 8 0 0 0 0 0 0 8 0.46 0.04 111 E -1 -1 0 4 -4 1 5 -2 -1 -4 -4 0 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 22 0 0 78 0 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.07 112 A 1 1 1 -1 -2 0 0 -1 -1 0 -1 3 -1 -2 -1 0 1 -2 -1 -1 16 8 8 1 0 1 1 2 0 9 2 36 0 1 1 2 9 0 1 1 0.14 0.02 113 T -1 0 0 3 -3 3 3 -2 -1 -3 -3 1 -2 -4 -2 0 1 -3 -2 -2 0 0 0 26 0 22 30 0 0 0 0 8 0 0 0 0 14 0 0 0 0.47 0.04 114 R -1 3 -1 1 -3 1 1 -2 2 -2 0 1 -1 -2 2 0 -1 -3 -2 -2 0 29 0 8 0 8 13 0 7 0 13 0 0 0 13 8 0 0 0 0 0.28 0.03 115 S 1 -1 0 4 -3 0 2 -1 -1 -3 -3 1 -2 -3 -1 2 0 -4 -3 -2 13 0 0 43 0 0 13 0 0 0 0 8 0 0 0 22 0 0 0 0 0.45 0.04 116 V 0 -2 0 -2 -1 -2 -2 -3 -2 2 1 -2 0 -1 -2 1 1 -3 -2 3 0 0 7 0 0 0 0 0 0 13 16 0 0 0 0 14 13 0 0 36 0.17 0.03 117 L 1 0 -1 -1 -2 3 2 -2 -1 -1 -1 2 -1 -3 -2 0 -1 -3 -2 -1 13 0 0 0 0 22 16 0 0 8 7 26 0 0 0 7 0 0 0 0 0.22 0.03 118 D -1 -2 3 5 -3 -1 0 -1 -1 0 -2 -1 -2 -3 -2 1 0 -4 -3 -2 0 0 15 52 0 0 0 0 0 13 0 0 0 0 0 20 0 0 0 0 0.48 0.05 119 D -1 -1 0 2 -3 2 2 2 3 -4 -3 0 -2 -3 3 0 -1 -3 -2 -3 0 0 0 14 0 13 14 24 13 0 0 0 0 0 13 8 0 0 0 0 0.38 0.03 120 K 1 1 1 3 -3 0 0 3 -1 -3 -3 2 -2 -3 -2 0 -1 -3 -3 -3 14 8 8 22 0 0 0 26 0 0 0 22 0 0 0 0 0 0 0 0 0.32 0.03 121 L 1 -2 -1 -2 -1 -2 -2 -2 -2 2 1 -2 0 -1 -2 1 2 -3 -2 2 14 0 0 0 0 0 0 0 0 22 14 0 0 0 0 13 24 0 0 13 0.16 0.02 122 V 1 -2 -2 -3 -2 -2 -2 1 -1 2 0 -2 2 0 -2 -1 0 -1 2 2 14 0 0 0 0 0 0 13 0 15 0 0 13 0 0 0 8 0 16 21 0.13 0.02 123 F -3 -3 -3 -4 -3 -3 -4 -4 -1 -1 0 -3 -1 7 -4 -3 -3 1 5 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 78 0 0 0 0 22 0 0.95 0.08 124 V 0 -3 -3 -4 -1 -3 -3 -3 -4 3 1 -3 1 -1 -3 -2 -1 -3 -2 4 8 0 0 0 0 0 0 0 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0.05 880 E -1 -1 0 4 -4 1 5 -2 -1 -4 -4 0 -3 -4 -2 -1 -1 -4 -3 -3 0 0 0 24 0 0 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0.82 0.07 881 N 1 -1 3 0 -2 0 2 -1 -1 -2 -2 -1 -2 2 -2 1 -1 -2 -1 -2 22 0 30 0 0 0 24 0 0 0 0 0 0 16 0 8 0 0 0 0 0.24 0.03 882 H -1 0 0 0 -3 2 4 -2 5 -3 -3 0 -2 -2 -2 -1 -1 -3 0 -3 1 1 0 1 0 10 51 1 31 1 1 1 0 0 1 1 1 0 0 1 0.56 0.05 883 L -1 -2 -2 -2 -2 -1 1 0 -2 1 3 -2 1 -1 -2 -2 -1 -2 -1 1 1 1 0 1 0 0 16 10 0 1 57 1 0 0 1 1 1 0 0 10 0.17 0.03 884 K -1 1 2 1 -4 1 4 -2 0 -3 -3 3 -2 -4 -2 0 -1 -3 -2 -3 0 0 18 0 0 0 39 0 0 0 0 43 0 0 0 0 0 0 0 0 0.50 0.04 885 D 1 2 0 2 -3 2 1 -2 4 -3 -3 2 -2 -3 -2 0 -1 -3 -1 -2 16 11 0 19 0 15 0 0 18 0 0 21 0 0 0 0 0 0 0 0 0.30 0.02 886 M -2 -2 -3 -3 -2 1 -2 -4 -2 1 4 -2 3 0 -3 -2 -1 -2 -1 0 0 0 0 0 0 15 0 0 0 0 76 0 9 0 0 0 0 0 0 0 0.37 0.03 887 T -1 0 -1 -1 -2 3 0 -2 -1 -1 1 2 0 -2 -2 0 1 -2 -2 -1 0 0 0 0 0 29 0 0 0 0 31 21 0 0 0 0 19 0 0 0 0.20 0.03 888 K -1 1 -1 0 -3 3 2 1 -1 -2 0 3 -1 -3 -2 -1 -1 -3 -2 -2 0 0 0 0 0 18 21 16 0 0 15 30 0 0 0 0 0 0 0 0 0.25 0.02 889 N 1 -1 5 3 -2 0 0 -1 0 -3 -3 -1 -2 -3 -2 1 0 -4 -2 -2 22 0 57 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.48 0.02 890 M -1 -2 -1 -2 -1 -1 -2 -3 -2 1 2 -1 3 -1 -2 0 3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 30 0 28 0 0 0 43 0 0 0 0.25 0.02 891 G 0 -3 -1 -2 -3 -2 -3 5 -2 -4 -3 -2 -3 -2 -3 -1 -2 7 -1 -3 0 0 0 0 0 0 0 79 0 0 0 0 0 0 0 0 0 21 0 0 1.02 0.03 892 V -1 -2 1 -2 -1 -2 -2 -3 -2 3 1 -2 3 -1 -3 -1 0 -3 -1 3 0 0 15 0 0 0 0 0 0 28 0 0 21 0 0 0 0 0 0 36 0.21 0.01 893 I -1 0 -2 -1 -2 0 2 -3 -2 3 0 2 0 -1 -2 -1 -1 -3 -2 1 0 0 0 0 0 0 23 0 0 53 0 24 0 0 0 0 0 0 0 0 0.15 0.01 894 A 2 0 -1 -2 -2 0 -1 3 -2 -1 -1 2 2 -2 -2 0 -1 -3 -2 -1 32 0 0 0 0 0 0 24 0 0 0 23 21 0 0 0 0 0 0 0 0.20 0.01 895 E -1 0 0 1 -4 2 5 -2 0 -3 -3 2 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 79 0 0 0 0 21 0 0 0 0 0 0 0 0 0.65 0.02 896 R -1 4 3 0 -3 3 1 -2 0 -3 -3 3 -1 -3 -2 0 -1 -3 -2 -3 0 32 21 0 0 24 0 0 0 0 0 23 0 0 0 0 0 0 0 0 0.45 0.01 897 M -1 -2 -3 -3 -2 -2 -2 -3 -3 2 1 -2 2 -1 5 -2 -1 -3 -2 2 0 0 0 0 0 0 0 0 0 21 0 0 21 0 31 0 0 0 0 28 0.45 0.01 898 I -1 3 -2 -2 -2 -1 -2 2 -2 1 1 0 0 -1 -3 -1 -1 -2 -2 0 0 31 0 0 0 0 0 21 0 21 28 0 0 0 0 0 0 0 0 0 0.15 0.00 899 E -1 -2 0 3 -3 0 2 2 -2 0 -2 -1 -1 -3 -2 -1 -1 -3 -2 1 0 0 0 31 0 0 21 21 0 0 0 0 0 0 0 0 0 0 0 28 0.24 0.00 900 A 1 -2 0 3 -1 -1 0 -2 -2 0 -1 -1 -1 -2 -2 0 2 -3 -2 2 21 0 0 28 0 0 0 0 0 0 0 0 0 0 0 0 21 0 0 31 0.17 0.00 901 V -1 -2 -2 -1 -2 0 2 -3 -2 1 -1 -1 -1 -2 5 -1 -1 -3 -2 2 0 0 0 0 0 0 28 0 0 0 0 0 0 0 31 0 0 0 0 42 0.44 0.01 902 D -1 -2 0 5 6 -1 1 -2 -2 -3 -3 -1 -3 -3 -2 -1 -1 -4 -3 -2 0 0 0 69 31 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.70 0.01 903 N -2 -1 6 1 -3 0 0 -1 1 -4 -4 0 -2 -3 -2 1 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.77 0.02 904 N 0 -1 5 1 -2 0 0 0 0 -3 -3 0 -2 -3 -2 3 1 -4 -2 -2 0 0 52 0 0 0 0 0 0 0 0 0 0 0 0 48 0 0 0 0 0.47 0.01 905 L -1 -2 -2 -3 -2 -1 -2 -3 5 1 3 -2 1 0 -3 -2 -1 -2 0 1 0 0 0 0 0 0 0 0 31 0 48 0 0 0 0 0 0 0 0 21 0.25 0.01 906 R 0 4 0 -1 -3 1 0 -1 -1 -3 -3 3 -2 -3 -1 2 0 -3 -2 -2 0 42 0 0 0 0 0 0 0 0 0 28 0 0 0 31 0 0 0 0 0.41 0.01 907 P 2 -2 -2 -2 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 7 0 -1 -4 -3 -2 28 0 0 0 0 0 0 0 0 0 0 0 0 0 72 0 0 0 0 0 1.35 0.01 908 K -1 1 0 -1 -2 1 0 -2 -1 -2 -2 4 -1 -3 -1 0 2 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 69 0 0 0 0 31 0 0 0 0.37 0.01 909 S 0 -1 0 -1 -1 -1 -1 -2 -2 0 1 -1 0 -2 -1 2 4 -3 -2 0 0 0 0 0 0 0 0 0 0 0 21 0 0 0 0 21 58 0 0 0 0.28 0.01 910 E -1 0 0 2 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00 K Lambda Standard Ungapped 0.1397 0.3243 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1397 0.3243 PSI Gapped 0.0410 0.2670