PSIBLAST 2.11.0+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Stephen F. Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: uniprot_sprot.fasta 571,864 sequences; 207,016,062 total letters Results from round 1 Query= sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein 3 OS=Homo sapiens OX=9606 GN=IFITM3 PE=1 SV=2 Length=133 Score E Sequences producing significant alignments: (Bits) Value sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein 3 O... 278 4e-97 sp|Q01629|IFM2_HUMAN Interferon-induced transmembrane protein 2 O... 248 2e-85 sp|C9JQL5|DSA2D_HUMAN Putative dispanin subfamily A member 2d OS=... 224 7e-76 sp|Q9CQW9|IFM3_MOUSE Interferon-induced transmembrane protein 3 O... 186 8e-61 sp|P26376|IFM3_RAT Interferon-induced transmembrane protein 3 OS=... 184 5e-60 sp|P13164|IFM1_HUMAN Interferon-induced transmembrane protein 1 O... 176 8e-57 sp|Q99J93|IFM2_MOUSE Interferon-induced transmembrane protein 2 O... 167 3e-53 sp|Q9D103|IFM1_MOUSE Interferon-induced transmembrane protein 1 O... 144 1e-44 sp|A6NNB3|IFM5_HUMAN Interferon-induced transmembrane protein 5 O... 84.0 1e-20 sp|Q91499|DSA2B_TORMA Dispanin subfamily A member 2b OS=Torpedo m... 81.3 9e-20 sp|O88728|IFM5_MOUSE Interferon-induced transmembrane protein 5 O... 76.6 1e-17 sp|A6NMD0|IFM10_HUMAN Interferon-induced transmembrane protein 10... 75.9 2e-16 sp|Q8BR26|IFM10_MOUSE Interferon-induced transmembrane protein 10... 74.3 4e-16 sp|Q5RAC1|PRRT2_PONAB Proline-rich transmembrane protein 2 OS=Pon... 49.7 1e-06 sp|D3ZFB6|PRRT2_RAT Proline-rich transmembrane protein 2 OS=Rattu... 48.9 2e-06 sp|Q7Z6L0|PRRT2_HUMAN Proline-rich transmembrane protein 2 OS=Hom... 48.5 3e-06 sp|E9PUL5|PRRT2_MOUSE Proline-rich transmembrane protein 2 OS=Mus... 48.5 3e-06 sp|A0A1B0GWB2|PRT1B_HUMAN Proline rich transmembrane protein 1B O... 38.9 0.005 sp|Q6NFU3|TIG_CORDI Trigger factor OS=Corynebacterium diphtheriae... 33.9 0.28 sp|Q6ZNR0|TMM91_HUMAN Transmembrane protein 91 OS=Homo sapiens OX... 31.2 1.7 sp|Q5E9S8|CDIN1_BOVIN CDAN1-interacting nuclease 1 OS=Bos taurus ... 31.6 1.7 sp|Q16643|DREB_HUMAN Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1... 31.6 2.0 sp|Q8C581|TMM91_MOUSE Transmembrane protein 91 OS=Mus musculus OX... 30.8 2.7 sp|Q3U4G0|CDIN1_MOUSE CDAN1-interacting nuclease 1 OS=Mus musculu... 30.0 5.9 sp|Q97CM5|DTDA_THEVO D-aminoacyl-tRNA deacylase OS=Thermoplasma v... 30.0 6.7 sp|Q4JQW3|TEG1_VZVO Tegument protein UL46 homolog OS=Varicella-zo... 30.0 7.0 sp|P09264|TEG1_VZVD Tegument protein UL46 homolog OS=Varicella-zo... 30.0 7.0 sp|O22920|CHX13_ARATH Cation/H(+) symporter 13 OS=Arabidopsis tha... 30.0 7.3 sp|Q9Y2V0|CDIN1_HUMAN CDAN1-interacting nuclease 1 OS=Homo sapien... 29.6 8.9 sp|Q8LPL3|ASO_ARATH L-ascorbate oxidase OS=Arabidopsis thaliana O... 29.6 9.0 sp|O15018|PDZD2_HUMAN PDZ domain-containing protein 2 OS=Homo sap... 29.6 9.1 >sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein 3 OS=Homo sapiens OX=9606 GN=IFITM3 PE=1 SV=2 Length=133 Score = 278 bits (710), Expect = 4e-97, Method: Compositional matrix adjust. Identities = 133/133 (100%), Positives = 133/133 (100%), Gaps = 0/133 (0%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW Sbjct 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL Sbjct 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120 Query 121 LIVIPVLIFQAYG 133 LIVIPVLIFQAYG Sbjct 121 LIVIPVLIFQAYG 133 >sp|Q01629|IFM2_HUMAN Interferon-induced transmembrane protein 2 OS=Homo sapiens OX=9606 GN=IFITM2 PE=1 SV=2 Length=132 Score = 248 bits (633), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 120/131 (92%), Positives = 123/131 (94%), Gaps = 1/131 (1%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 MNH VQTF SPVNSGQPPNYEMLKEE EVA+LG PHNPAPP STVIHIRSETSVPDHVVW Sbjct 1 MNHIVQTF-SPVNSGQPPNYEMLKEEQEVAMLGVPHNPAPPMSTVIHIRSETSVPDHVVW 59 Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120 SLFNTLFMN CCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI MTIL Sbjct 60 SLFNTLFMNTCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGIFMTIL 119 Query 121 LIVIPVLIFQA 131 LI+IPVL+ QA Sbjct 120 LIIIPVLVVQA 130 >sp|C9JQL5|DSA2D_HUMAN Putative dispanin subfamily A member 2d OS=Homo sapiens OX=9606 PE=5 SV=1 Length=133 Score = 224 bits (570), Expect = 7e-76, Method: Compositional matrix adjust. Identities = 124/132 (94%), Positives = 129/132 (98%), Gaps = 0/132 (0%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 MNHTVQTFFSPVNSGQPPNYEMLKEEH+VAVLG PHNPAPPTSTVIHIRS+TSVP HVVW Sbjct 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHKVAVLGVPHNPAPPTSTVIHIRSKTSVPHHVVW 60 Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVG+VTGAQAYAST KCLNIWALILGILMTIL Sbjct 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGNVTGAQAYASTTKCLNIWALILGILMTIL 120 Query 121 LIVIPVLIFQAY 132 LI+IPVLIFQA+ Sbjct 121 LIIIPVLIFQAH 132 >sp|Q9CQW9|IFM3_MOUSE Interferon-induced transmembrane protein 3 OS=Mus musculus OX=10090 GN=Ifitm3 PE=1 SV=1 Length=137 Score = 186 bits (472), Expect = 8e-61, Method: Compositional matrix adjust. Identities = 87/117 (74%), Positives = 97/117 (83%), Gaps = 0/117 (0%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 MNHT Q F + + GQPPNYE +KEE+EVA +GAPH A +TVI++ E SVPDHVVW Sbjct 1 MNHTSQAFITAASGGQPPNYERIKEEYEVAEMGAPHGSASVRTTVINMPREVSVPDHVVW 60 Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILM 117 SLFNTLFMN CCLGFIA+AYSVKSRDRKMVGDVTGAQAYASTAKCLNI L+L ILM Sbjct 61 SLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDVTGAQAYASTAKCLNISTLVLSILM 117 >sp|P26376|IFM3_RAT Interferon-induced transmembrane protein 3 OS=Rattus norvegicus OX=10116 GN=ifitm3 PE=2 SV=1 Length=137 Score = 184 bits (467), Expect = 5e-60, Method: Compositional matrix adjust. Identities = 86/117 (74%), Positives = 97/117 (83%), Gaps = 0/117 (0%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 MNHT Q F + GQPPNYE +KEE+EV+ LGAPH A +TVI++ E SVPDHVVW Sbjct 1 MNHTSQAFVNAATGGQPPNYERIKEEYEVSELGAPHGSASVRTTVINMPREVSVPDHVVW 60 Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILM 117 SLFNTLFMN CCLGFIA+AYSVKSRDRKMVGD+TGAQAYASTAKCLNI +L+L ILM Sbjct 61 SLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDMTGAQAYASTAKCLNISSLVLSILM 117 >sp|P13164|IFM1_HUMAN Interferon-induced transmembrane protein 1 OS=Homo sapiens OX=9606 GN=IFITM1 PE=1 SV=3 Length=125 Score = 176 bits (445), Expect = 8e-57, Method: Compositional matrix adjust. Identities = 88/106 (83%), Positives = 93/106 (88%), Gaps = 0/106 (0%) Query 22 MLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYS 81 M KEEHEVAVLG P + P STVI+I SETSVPDHVVWSLFNTLF+N CCLGFIAFAYS Sbjct 1 MHKEEHEVAVLGPPPSTILPRSTVINIHSETSVPDHVVWSLFNTLFLNWCCLGFIAFAYS 60 Query 82 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVIPVL 127 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTI I++ V Sbjct 61 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIGFILLLVF 106 >sp|Q99J93|IFM2_MOUSE Interferon-induced transmembrane protein 2 OS=Mus musculus OX=10090 GN=Ifitm2 PE=1 SV=1 Length=144 Score = 167 bits (422), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 84/137 (61%), Positives = 100/137 (73%), Gaps = 5/137 (4%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 M+H Q F S N+G PP+YE +KEE+ V LG P N A +TVI++ E SVPDHVVW Sbjct 1 MSHNSQAFLS-TNAGLPPSYETIKEEYGVTELGEPSNSAVVRTTVINMPREVSVPDHVVW 59 Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILM--- 117 SLFNTLF N CCLGF+A+AYSVKSRDRKMVGDV GAQAYASTAKCLNI +LI ILM Sbjct 60 SLFNTLFFNACCLGFVAYAYSVKSRDRKMVGDVVGAQAYASTAKCLNISSLIFSILMVII 119 Query 118 -TILLIVIPVLIFQAYG 133 I+ V++FQ++ Sbjct 120 CIIIFSTTSVVVFQSFA 136 >sp|Q9D103|IFM1_MOUSE Interferon-induced transmembrane protein 1 OS=Mus musculus OX=10090 GN=Ifitm1 PE=2 SV=1 Length=106 Score = 144 bits (363), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 70/103 (68%), Positives = 82/103 (80%), Gaps = 1/103 (1%) Query 22 MLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYS 81 M KE+ EV VLG+PH T+T I++ E S PDHVVWSLFNTLFMN CCLGF+A+AYS Sbjct 1 MPKEQQEVVVLGSPHISTSATATTINM-PEISTPDHVVWSLFNTLFMNFCCLGFVAYAYS 59 Query 82 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVI 124 VKSRDRKMVGD TGAQA+ASTAKCLNI +L IL I++IV+ Sbjct 60 VKSRDRKMVGDTTGAQAFASTAKCLNISSLFFTILTAIVVIVV 102 >sp|A6NNB3|IFM5_HUMAN Interferon-induced transmembrane protein 5 OS=Homo sapiens OX=9606 GN=IFITM5 PE=1 SV=1 Length=132 Score = 84.0 bits (206), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 40/86 (47%), Positives = 55/86 (64%), Gaps = 15/86 (17%) Query 27 HEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRD 86 H LGAPH PP DH++WS+F+TL++N CCLGF+A AYS+K+RD Sbjct 21 HTALTLGAPH---PPPR------------DHLIWSVFSTLYLNLCCLGFLALAYSIKARD 65 Query 87 RKMVGDVTGAQAYASTAKCLNIWALI 112 +K+VGD+ A+ + S AKC NI A + Sbjct 66 QKVVGDLEAARRFGSKAKCYNILAAM 91 >sp|Q91499|DSA2B_TORMA Dispanin subfamily A member 2b OS=Torpedo marmorata OX=7788 PE=2 SV=1 Length=107 Score = 81.3 bits (199), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 35/59 (59%), Positives = 44/59 (75%), Gaps = 0/59 (0%) Query 54 VPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALI 112 + DH+ WS+FN +MN CCLG A +SVKSRDRK+VGDV GA+ Y STA+ LNI A + Sbjct 24 IRDHLPWSIFNLFYMNVCCLGLTAMIFSVKSRDRKVVGDVEGARHYGSTARSLNIAATV 82 >sp|O88728|IFM5_MOUSE Interferon-induced transmembrane protein 5 OS=Mus musculus OX=10090 GN=Ifitm5 PE=1 SV=1 Length=134 Score = 76.6 bits (187), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 34/86 (40%), Positives = 54/86 (63%), Gaps = 9/86 (10%) Query 36 HNPAPPTSTVIHIRSETSVP---------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRD 86 +P P+S + T++ DH++WS+F+T+++N CCLGF+A +SVK+RD Sbjct 8 EDPRAPSSRKADAAAHTALSMGTPGPTPRDHMLWSVFSTMYLNLCCLGFLALVHSVKARD 67 Query 87 RKMVGDVTGAQAYASTAKCLNIWALI 112 +KM G++ A+ Y S AKC NI A + Sbjct 68 QKMAGNLEAARQYGSKAKCYNILAAM 93 >sp|A6NMD0|IFM10_HUMAN Interferon-induced transmembrane protein 10 OS=Homo sapiens OX=9606 GN=IFITM10 PE=1 SV=1 Length=228 Score = 75.9 bits (185), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 43/112 (38%), Positives = 66/112 (59%), Gaps = 11/112 (10%) Query 14 SGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETS-VPDHVVWSLFNTLFMNPCC 72 +G PP + L E+ + NP +TVI + +T+ V D+ +WS+FN +++N CC Sbjct 119 AGAPPACKHLAEKKTMT------NP----TTVIEVYPDTTEVNDYYLWSIFNFVYLNFCC 168 Query 73 LGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVI 124 LGFIA AYS+K RD+K++ D+ GA A TA+ NI + L IL+ + Sbjct 169 LGFIALAYSLKVRDKKLLNDLNGAVEDAKTARLFNITSSALAASCIILVFIF 220 >sp|Q8BR26|IFM10_MOUSE Interferon-induced transmembrane protein 10 OS=Mus musculus OX=10090 GN=Ifitm10 PE=2 SV=3 Length=201 Score = 74.3 bits (181), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 36/83 (43%), Positives = 55/83 (66%), Gaps = 1/83 (1%) Query 43 STVIHIRSETS-VPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYAS 101 +TVI + +T+ V D+ +WS+FN +++N CCLGFIA AYS+K RD+K++ D+ GA A Sbjct 111 TTVIEVYPDTTEVNDYYLWSIFNFVYLNFCCLGFIALAYSLKVRDKKLLNDLNGAVEDAK 170 Query 102 TAKCLNIWALILGILMTILLIVI 124 TA+ NI + L IL+ + Sbjct 171 TARLFNITSSALAASCIILIFIF 193 >sp|Q5RAC1|PRRT2_PONAB Proline-rich transmembrane protein 2 OS=Pongo abelii OX=9601 GN=PRRT2 PE=2 SV=1 Length=340 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 14/141 (10%) Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55 H+ + SP +G PP + L EE + + H +P S H S+ + P Sbjct 201 HSPPSKKSPPANGAPPRVLQQLVEEDRMGRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGE 260 Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109 D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I Sbjct 261 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 319 Query 110 ALILGILMTILLIVIPVLIFQ 130 AL+ G+L+ I VI + +++ Sbjct 320 ALVGGVLIIIASCVINLGVYK 340 >sp|D3ZFB6|PRRT2_RAT Proline-rich transmembrane protein 2 OS=Rattus norvegicus OX=10116 GN=Prrt2 PE=1 SV=1 Length=344 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 40/141 (28%), Positives = 67/141 (48%), Gaps = 14/141 (10%) Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55 H+ + +P +G PP + L EE + H +P S H S+ + P Sbjct 205 HSPPSTKTPPANGAPPRVLQKLVEEDRIGRAHGGHPGSPRGSLSRHPSSQLAGPGVEGGE 264 Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109 D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I Sbjct 265 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 323 Query 110 ALILGILMTILLIVIPVLIFQ 130 AL+ G+L+ I VI + +++ Sbjct 324 ALVGGVLIIIASCVINLGVYK 344 >sp|Q7Z6L0|PRRT2_HUMAN Proline-rich transmembrane protein 2 OS=Homo sapiens OX=9606 GN=PRRT2 PE=1 SV=1 Length=340 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 14/141 (10%) Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55 H+ + SP +G PP + L EE + + H +P S H S+ + P Sbjct 201 HSPPSKKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGE 260 Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109 D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I Sbjct 261 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 319 Query 110 ALILGILMTILLIVIPVLIFQ 130 AL+ G+L+ I VI + +++ Sbjct 320 ALVGGVLIIIASCVINLGVYK 340 >sp|E9PUL5|PRRT2_MOUSE Proline-rich transmembrane protein 2 OS=Mus musculus OX=10090 GN=Prrt2 PE=1 SV=1 Length=346 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 40/141 (28%), Positives = 67/141 (48%), Gaps = 14/141 (10%) Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55 H+ + +P +G PP + L EE + H +P S H S+ + P Sbjct 207 HSPPSTKTPPANGAPPRVLQKLVEEDRIGRAHGGHPGSPRGSLSRHPSSQLAGPGVEGGE 266 Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109 D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I Sbjct 267 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 325 Query 110 ALILGILMTILLIVIPVLIFQ 130 AL+ G+L+ I VI + +++ Sbjct 326 ALVGGVLIIIASCVINLGVYK 346 >sp|A0A1B0GWB2|PRT1B_HUMAN Proline rich transmembrane protein 1B OS=Homo sapiens OX=9606 GN=PRRT1B PE=1 SV=1 Length=263 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 21/70 (30%), Positives = 40/70 (57%), Gaps = 5/70 (7%) Query 56 DHVVWSLFNTLFMNPCCL--GFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALIL 113 D+++ S+ TLF CCL G IA YS ++R GD+ A+ + A+ L +++L+ Sbjct 188 DYMMESVLVTLF---CCLLTGLIAIVYSHEARAALGRGDLAQAEEASRKARSLVLFSLLF 244 Query 114 GILMTILLIV 123 G+ ++ ++ Sbjct 245 GVFVSTSWVI 254 >sp|Q6NFU3|TIG_CORDI Trigger factor OS=Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) OX=257309 GN=tig PE=3 SV=1 Length=448 Score = 33.9 bits (76), Expect = 0.28, Method: Composition-based stats. Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 8/53 (15%) Query 12 VNSGQPPNYEMLKEEHEVAVLGAPH--------NPAPPTSTVIHIRSETSVPD 56 +N P Y+ + EE+E+ VLG PH N + + +R E +VPD Sbjct 68 INDMLPTRYQQVVEENELVVLGQPHIDITKLEDNEVVEFTAEVDVRPEITVPD 120 >sp|Q6ZNR0|TMM91_HUMAN Transmembrane protein 91 OS=Homo sapiens OX=9606 GN=TMEM91 PE=1 SV=1 Length=172 Score = 31.2 bits (69), Expect = 1.7, Method: Compositional matrix adjust. Identities = 20/63 (32%), Positives = 32/63 (51%), Gaps = 7/63 (11%) Query 56 DHVVWSLFNTLFMNPCC---LGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALI 112 DH+ ++F+ L CC +G AF + K+ GD+ GA A + A L + A+ Sbjct 94 DHLGLAVFSML----CCFWPVGIAAFCLAQKTNKAWAKGDIQGAGAASRRAFLLGVLAVG 149 Query 113 LGI 115 LG+ Sbjct 150 LGV 152 >sp|Q5E9S8|CDIN1_BOVIN CDAN1-interacting nuclease 1 OS=Bos taurus OX=9913 GN=CDIN1 PE=2 SV=1 Length=281 Score = 31.6 bits (70), Expect = 1.7, Method: Compositional matrix adjust. Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 2/41 (5%) Query 36 HNPAPPTSTVIH--IRSETSVPDHVVWSLFNTLFMNPCCLG 74 H APP+ +VI+ +R + +PD V+ + +N CC G Sbjct 111 HEEAPPSKSVINSMLRDPSQIPDGVLANQVYQCIVNDCCYG 151 >sp|Q16643|DREB_HUMAN Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 Length=649 Score = 31.6 bits (70), Expect = 2.0, Method: Composition-based stats. Identities = 19/52 (37%), Positives = 22/52 (42%), Gaps = 0/52 (0%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSET 52 M Q P G P M E E AVL AP PA +T IH ++T Sbjct 401 MEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDAADT 452 >sp|Q8C581|TMM91_MOUSE Transmembrane protein 91 OS=Mus musculus OX=10090 GN=Tmem91 PE=2 SV=1 Length=172 Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 32/63 (51%), Gaps = 7/63 (11%) Query 56 DHVVWSLFNTLFMNPCC---LGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALI 112 DH+ ++F+ L CC +G AF + K+ GDV GA A + A L + A+ Sbjct 94 DHLGLAVFSVL----CCFWPVGIAAFCLAHKTNKAWAKGDVQGAGAASRRAFLLGVLAVG 149 Query 113 LGI 115 LG+ Sbjct 150 LGL 152 >sp|Q3U4G0|CDIN1_MOUSE CDAN1-interacting nuclease 1 OS=Mus musculus OX=10090 GN=Cdin1 PE=2 SV=2 Length=281 Score = 30.0 bits (66), Expect = 5.9, Method: Compositional matrix adjust. Identities = 13/41 (32%), Positives = 22/41 (54%), Gaps = 2/41 (5%) Query 36 HNPAPPTSTVIH--IRSETSVPDHVVWSLFNTLFMNPCCLG 74 H PP+ +VI+ +R + +PD V+ + +N CC G Sbjct 111 HEQTPPSKSVINSMLRDPSQIPDGVLANQVYQCIVNDCCYG 151 >sp|Q97CM5|DTDA_THEVO D-aminoacyl-tRNA deacylase OS=Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) OX=273116 GN=dtdA PE=3 SV=1 Length=256 Score = 30.0 bits (66), Expect = 6.7, Method: Compositional matrix adjust. Identities = 14/48 (29%), Positives = 22/48 (46%), Gaps = 0/48 (0%) Query 47 HIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVT 94 HI S+ D W + + + P C GF+ +SR R MV ++ Sbjct 199 HIISKHDHDDLEEWQIKDAVEKTPSCKGFLVDRKGTRSRVRDMVKSIS 246 >sp|Q4JQW3|TEG1_VZVO Tegument protein UL46 homolog OS=Varicella-zoster virus (strain Oka vaccine) OX=341980 GN=ORF12 PE=3 SV=1 Length=661 Score = 30.0 bits (66), Expect = 7.0, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 0/53 (0%) Query 6 QTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHV 58 T SPV+ P +Y +K E+E V + S + HI ++ S+ DHV Sbjct 545 HTDGSPVDPTYPDHYTRIKAEYEGPVRDESNTMFDQRSDLRHIETQASLNDHV 597 >sp|P09264|TEG1_VZVD Tegument protein UL46 homolog OS=Varicella-zoster virus (strain Dumas) OX=10338 GN=ORF12 PE=3 SV=1 Length=661 Score = 30.0 bits (66), Expect = 7.0, Method: Compositional matrix adjust. Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 0/53 (0%) Query 6 QTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHV 58 T SPV+ P +Y +K E+E V + S + HI ++ S+ DHV Sbjct 545 HTDGSPVDPTYPDHYTRIKAEYEGPVRDESNTMFDQRSDLRHIETQASLNDHV 597 >sp|O22920|CHX13_ARATH Cation/H(+) symporter 13 OS=Arabidopsis thaliana OX=3702 GN=CHX13 PE=1 SV=1 Length=831 Score = 30.0 bits (66), Expect = 7.3, Method: Compositional matrix adjust. Identities = 26/111 (23%), Positives = 47/111 (42%), Gaps = 27/111 (24%) Query 32 LGAPHNPAPPTSTVIHIRSETSVP-DHVVWSLFNTL------------FMNPCCLGFIAF 78 +G P + TS+ I + S TS P V + N L + C F+A Sbjct 172 MGLPSDVISCTSSAISLSSMTSFPVTTTVLAELNILNSELGRLATHCSMVCEVCSWFVAL 231 Query 79 AYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVIPVLIF 129 A+++ +RDR M L ++I+G+L+ I + P++++ Sbjct 232 AFNLYTRDRTMTS--------------LYALSMIIGLLLVIYFVFRPIIVW 268 >sp|Q9Y2V0|CDIN1_HUMAN CDAN1-interacting nuclease 1 OS=Homo sapiens OX=9606 GN=CDIN1 PE=1 SV=2 Length=281 Score = 29.6 bits (65), Expect = 8.9, Method: Compositional matrix adjust. Identities = 12/41 (29%), Positives = 22/41 (54%), Gaps = 2/41 (5%) Query 36 HNPAPPTSTVIH--IRSETSVPDHVVWSLFNTLFMNPCCLG 74 H PP+ ++I+ +R + +PD V+ + +N CC G Sbjct 111 HEETPPSKSIINSMLRDPSQIPDGVLANQVYQCIVNDCCYG 151 >sp|Q8LPL3|ASO_ARATH L-ascorbate oxidase OS=Arabidopsis thaliana OX=3702 GN=AAO PE=1 SV=1 Length=573 Score = 29.6 bits (65), Expect = 9.0, Method: Compositional matrix adjust. Identities = 25/101 (25%), Positives = 43/101 (43%), Gaps = 9/101 (9%) Query 30 AVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCC--LGFIAF----AYSVK 83 A G P P +I + ++ D+ WS+ N P LG I + AY +K Sbjct 350 AAKGYPKPPEKSHDQLILLNTQNLYEDYTKWSINNVSLSVPVTPYLGSIRYGLKSAYDLK 409 Query 84 SRDRKMV---GDVTGAQAYASTAKCLNIWALILGILMTILL 121 S +K++ D+ +T K I+ GI++ ++L Sbjct 410 SPAKKLIMDNYDIMKPPPNPNTTKGSGIYNFAFGIVVDVIL 450 >sp|O15018|PDZD2_HUMAN PDZ domain-containing protein 2 OS=Homo sapiens OX=9606 GN=PDZD2 PE=1 SV=4 Length=2839 Score = 29.6 bits (65), Expect = 9.1, Method: Composition-based stats. Identities = 15/52 (29%), Positives = 24/52 (46%), Gaps = 0/52 (0%) Query 4 TVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP 55 +++TF SP+ S +P + + +AVL P P T R+E P Sbjct 1978 SIRTFVSPLTSPKPVPEQGMWSRFHMAVLSEPDRGCPTTPKSPKCRAEGRAP 2029 Lambda K H a alpha 0.324 0.137 0.428 0.792 4.96 Gapped Lambda K H a alpha sigma 0.267 0.0410 0.140 1.90 42.6 43.6 Effective search space used: 5113651884 Results from round 2 Query= sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein 3 OS=Homo sapiens OX=9606 GN=IFITM3 PE=1 SV=2 Length=133 Score E Sequences producing significant alignments: (Bits) Value Sequences used in model and found again: sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein 3 O... 213 2e-71 sp|Q01629|IFM2_HUMAN Interferon-induced transmembrane protein 2 O... 198 7e-66 sp|C9JQL5|DSA2D_HUMAN Putative dispanin subfamily A member 2d OS=... 178 1e-57 sp|Q9CQW9|IFM3_MOUSE Interferon-induced transmembrane protein 3 O... 176 8e-57 sp|P26376|IFM3_RAT Interferon-induced transmembrane protein 3 OS=... 173 8e-56 sp|Q99J93|IFM2_MOUSE Interferon-induced transmembrane protein 2 O... 165 2e-52 sp|P13164|IFM1_HUMAN Interferon-induced transmembrane protein 1 O... 159 2e-50 sp|Q5RAC1|PRRT2_PONAB Proline-rich transmembrane protein 2 OS=Pon... 149 1e-43 sp|Q7Z6L0|PRRT2_HUMAN Proline-rich transmembrane protein 2 OS=Hom... 145 2e-42 sp|D3ZFB6|PRRT2_RAT Proline-rich transmembrane protein 2 OS=Rattu... 144 4e-42 sp|E9PUL5|PRRT2_MOUSE Proline-rich transmembrane protein 2 OS=Mus... 144 5e-42 sp|Q9D103|IFM1_MOUSE Interferon-induced transmembrane protein 1 O... 135 5e-41 sp|A6NMD0|IFM10_HUMAN Interferon-induced transmembrane protein 10... 128 8e-37 sp|Q8BR26|IFM10_MOUSE Interferon-induced transmembrane protein 10... 121 3e-34 sp|A6NNB3|IFM5_HUMAN Interferon-induced transmembrane protein 5 O... 103 4e-28 sp|O88728|IFM5_MOUSE Interferon-induced transmembrane protein 5 O... 100 3e-27 sp|Q91499|DSA2B_TORMA Dispanin subfamily A member 2b OS=Torpedo m... 96.7 6e-26 Sequences not found previously or not previously below threshold: sp|Q6DFT4|TARG1_XENTR Trafficking regulator of GLUT4 1 OS=Xenopus... 62.1 1e-11 sp|D3Z1U7|TM233_MOUSE Transmembrane protein 233 OS=Mus musculus O... 50.5 7e-08 sp|B4DJY2|TM233_HUMAN Transmembrane protein 233 OS=Homo sapiens O... 50.1 1e-07 sp|A0A1B0GWB2|PRT1B_HUMAN Proline rich transmembrane protein 1B O... 46.7 1e-05 sp|Q2MHH0|TARG1_RAT Trafficking regulator of GLUT4 1 OS=Rattus no... 44.0 7e-05 sp|Q8C838|TARG1_MOUSE Trafficking regulator of GLUT4 1 OS=Mus mus... 43.2 9e-05 sp|Q6MG82|PRRT1_RAT Proline-rich transmembrane protein 1 OS=Rattu... 41.3 8e-04 sp|O35449|PRRT1_MOUSE Proline-rich transmembrane protein 1 OS=Mus... 41.3 8e-04 sp|Q8IXB3|TARG1_HUMAN Trafficking regulator of GLUT4 1 OS=Homo sa... 40.9 8e-04 sp|Q99946|PRRT1_HUMAN Proline-rich transmembrane protein 1 OS=Hom... 40.9 0.001 sp|Q8C581|TMM91_MOUSE Transmembrane protein 91 OS=Mus musculus OX... 39.3 0.002 sp|Q6ZNR0|TMM91_HUMAN Transmembrane protein 91 OS=Homo sapiens OX... 39.3 0.003 sp|Q4R532|SYNG1_MACFA Synapse differentiation-inducing gene prote... 35.9 0.061 sp|Q6NFU3|TIG_CORDI Trigger factor OS=Corynebacterium diphtheriae... 35.9 0.066 sp|Q9H7V2|SYNG1_HUMAN Synapse differentiation-inducing gene prote... 35.5 0.067 sp|Q58DZ9|SYNG1_RAT Synapse differentiation-inducing gene protein... 35.1 0.097 sp|A2ANU3|SYNG1_MOUSE Synapse differentiation-inducing gene prote... 35.1 0.10 sp|Q08DM6|SYNG1_BOVIN Synapse differentiation-inducing gene prote... 34.7 0.13 sp|A4IFJ1|SYN1L_BOVIN Synapse differentiation-inducing gene prote... 32.4 0.99 sp|Q3USQ7|SYN1L_MOUSE Synapse differentiation-inducing gene prote... 32.0 1.1 sp|P11947|COX1_TETPY Cytochrome c oxidase subunit 1 OS=Tetrahymen... 32.0 1.4 sp|A6NDD5|SYN1L_HUMAN Synapse differentiation-inducing gene prote... 31.6 1.7 sp|P05489|COX1_PARTE Cytochrome c oxidase subunit 1 OS=Paramecium... 31.6 2.2 sp|A0A396JU32|ENOD2_MEDTR Early nodule-specific protein 2 OS=Medi... 30.9 3.6 sp|Q16643|DREB_HUMAN Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1... 30.9 4.0 sp|P49796|RGS3_HUMAN Regulator of G-protein signaling 3 OS=Homo s... 30.9 4.1 sp|Q66HA5|C2D1A_RAT Coiled-coil and C2 domain-containing protein ... 30.1 6.1 sp|P10637|TAU_MOUSE Microtubule-associated protein tau OS=Mus mus... 30.1 6.8 sp|P19332|TAU_RAT Microtubule-associated protein tau OS=Rattus no... 29.7 8.3 sp|Q5TZE2|SYN1L_DANRE Synapse differentiation-inducing gene prote... 29.3 9.7 >sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein 3 OS=Homo sapiens OX=9606 GN=IFITM3 PE=1 SV=2 Length=133 Score = 213 bits (541), Expect = 2e-71, Method: Composition-based stats. Identities = 133/133 (100%), Positives = 133/133 (100%), Gaps = 0/133 (0%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW Sbjct 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL Sbjct 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120 Query 121 LIVIPVLIFQAYG 133 LIVIPVLIFQAYG Sbjct 121 LIVIPVLIFQAYG 133 >sp|Q01629|IFM2_HUMAN Interferon-induced transmembrane protein 2 OS=Homo sapiens OX=9606 GN=IFITM2 PE=1 SV=2 Length=132 Score = 198 bits (504), Expect = 7e-66, Method: Composition-based stats. Identities = 120/131 (92%), Positives = 123/131 (94%), Gaps = 1/131 (1%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 MNH VQTF SPVNSGQPPNYEMLKEE EVA+LG PHNPAPP STVIHIRSETSVPDHVVW Sbjct 1 MNHIVQTF-SPVNSGQPPNYEMLKEEQEVAMLGVPHNPAPPMSTVIHIRSETSVPDHVVW 59 Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120 SLFNTLFMN CCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI MTIL Sbjct 60 SLFNTLFMNTCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGIFMTIL 119 Query 121 LIVIPVLIFQA 131 LI+IPVL+ QA Sbjct 120 LIIIPVLVVQA 130 >sp|C9JQL5|DSA2D_HUMAN Putative dispanin subfamily A member 2d OS=Homo sapiens OX=9606 PE=5 SV=1 Length=133 Score = 178 bits (451), Expect = 1e-57, Method: Composition-based stats. Identities = 124/132 (94%), Positives = 129/132 (98%), Gaps = 0/132 (0%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 MNHTVQTFFSPVNSGQPPNYEMLKEEH+VAVLG PHNPAPPTSTVIHIRS+TSVP HVVW Sbjct 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHKVAVLGVPHNPAPPTSTVIHIRSKTSVPHHVVW 60 Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVG+VTGAQAYAST KCLNIWALILGILMTIL Sbjct 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGNVTGAQAYASTTKCLNIWALILGILMTIL 120 Query 121 LIVIPVLIFQAY 132 LI+IPVLIFQA+ Sbjct 121 LIIIPVLIFQAH 132 >sp|Q9CQW9|IFM3_MOUSE Interferon-induced transmembrane protein 3 OS=Mus musculus OX=10090 GN=Ifitm3 PE=1 SV=1 Length=137 Score = 176 bits (445), Expect = 8e-57, Method: Composition-based stats. Identities = 87/117 (74%), Positives = 97/117 (83%), Gaps = 0/117 (0%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 MNHT Q F + + GQPPNYE +KEE+EVA +GAPH A +TVI++ E SVPDHVVW Sbjct 1 MNHTSQAFITAASGGQPPNYERIKEEYEVAEMGAPHGSASVRTTVINMPREVSVPDHVVW 60 Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILM 117 SLFNTLFMN CCLGFIA+AYSVKSRDRKMVGDVTGAQAYASTAKCLNI L+L ILM Sbjct 61 SLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDVTGAQAYASTAKCLNISTLVLSILM 117 >sp|P26376|IFM3_RAT Interferon-induced transmembrane protein 3 OS=Rattus norvegicus OX=10116 GN=ifitm3 PE=2 SV=1 Length=137 Score = 173 bits (439), Expect = 8e-56, Method: Composition-based stats. Identities = 86/117 (74%), Positives = 97/117 (83%), Gaps = 0/117 (0%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 MNHT Q F + GQPPNYE +KEE+EV+ LGAPH A +TVI++ E SVPDHVVW Sbjct 1 MNHTSQAFVNAATGGQPPNYERIKEEYEVSELGAPHGSASVRTTVINMPREVSVPDHVVW 60 Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILM 117 SLFNTLFMN CCLGFIA+AYSVKSRDRKMVGD+TGAQAYASTAKCLNI +L+L ILM Sbjct 61 SLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDMTGAQAYASTAKCLNISSLVLSILM 117 >sp|Q99J93|IFM2_MOUSE Interferon-induced transmembrane protein 2 OS=Mus musculus OX=10090 GN=Ifitm2 PE=1 SV=1 Length=144 Score = 165 bits (418), Expect = 2e-52, Method: Composition-based stats. Identities = 84/137 (61%), Positives = 100/137 (73%), Gaps = 5/137 (4%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60 M+H Q F S N+G PP+YE +KEE+ V LG P N A +TVI++ E SVPDHVVW Sbjct 1 MSHNSQAFLS-TNAGLPPSYETIKEEYGVTELGEPSNSAVVRTTVINMPREVSVPDHVVW 59 Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMT-- 118 SLFNTLF N CCLGF+A+AYSVKSRDRKMVGDV GAQAYASTAKCLNI +LI ILM Sbjct 60 SLFNTLFFNACCLGFVAYAYSVKSRDRKMVGDVVGAQAYASTAKCLNISSLIFSILMVII 119 Query 119 --ILLIVIPVLIFQAYG 133 I+ V++FQ++ Sbjct 120 CIIIFSTTSVVVFQSFA 136 >sp|P13164|IFM1_HUMAN Interferon-induced transmembrane protein 1 OS=Homo sapiens OX=9606 GN=IFITM1 PE=1 SV=3 Length=125 Score = 159 bits (403), Expect = 2e-50, Method: Composition-based stats. Identities = 88/106 (83%), Positives = 93/106 (88%), Gaps = 0/106 (0%) Query 22 MLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYS 81 M KEEHEVAVLG P + P STVI+I SETSVPDHVVWSLFNTLF+N CCLGFIAFAYS Sbjct 1 MHKEEHEVAVLGPPPSTILPRSTVINIHSETSVPDHVVWSLFNTLFLNWCCLGFIAFAYS 60 Query 82 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVIPVL 127 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTI I++ V Sbjct 61 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIGFILLLVF 106 >sp|Q5RAC1|PRRT2_PONAB Proline-rich transmembrane protein 2 OS=Pongo abelii OX=9601 GN=PRRT2 PE=2 SV=1 Length=340 Score = 149 bits (375), Expect = 1e-43, Method: Composition-based stats. Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 14/141 (10%) Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55 H+ + SP +G PP + L EE + + H +P S H S+ + P Sbjct 201 HSPPSKKSPPANGAPPRVLQQLVEEDRMGRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGE 260 Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109 D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I Sbjct 261 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 319 Query 110 ALILGILMTILLIVIPVLIFQ 130 AL+ G+L+ I VI + +++ Sbjct 320 ALVGGVLIIIASCVINLGVYK 340 >sp|Q7Z6L0|PRRT2_HUMAN Proline-rich transmembrane protein 2 OS=Homo sapiens OX=9606 GN=PRRT2 PE=1 SV=1 Length=340 Score = 145 bits (366), Expect = 2e-42, Method: Composition-based stats. Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 14/141 (10%) Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55 H+ + SP +G PP + L EE + + H +P S H S+ + P Sbjct 201 HSPPSKKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGE 260 Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109 D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I Sbjct 261 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 319 Query 110 ALILGILMTILLIVIPVLIFQ 130 AL+ G+L+ I VI + +++ Sbjct 320 ALVGGVLIIIASCVINLGVYK 340 >sp|D3ZFB6|PRRT2_RAT Proline-rich transmembrane protein 2 OS=Rattus norvegicus OX=10116 GN=Prrt2 PE=1 SV=1 Length=344 Score = 144 bits (364), Expect = 4e-42, Method: Composition-based stats. Identities = 40/141 (28%), Positives = 67/141 (48%), Gaps = 14/141 (10%) Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55 H+ + +P +G PP + L EE + H +P S H S+ + P Sbjct 205 HSPPSTKTPPANGAPPRVLQKLVEEDRIGRAHGGHPGSPRGSLSRHPSSQLAGPGVEGGE 264 Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109 D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I Sbjct 265 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 323 Query 110 ALILGILMTILLIVIPVLIFQ 130 AL+ G+L+ I VI + +++ Sbjct 324 ALVGGVLIIIASCVINLGVYK 344 >sp|E9PUL5|PRRT2_MOUSE Proline-rich transmembrane protein 2 OS=Mus musculus OX=10090 GN=Prrt2 PE=1 SV=1 Length=346 Score = 144 bits (364), Expect = 5e-42, Method: Composition-based stats. Identities = 40/141 (28%), Positives = 67/141 (48%), Gaps = 14/141 (10%) Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55 H+ + +P +G PP + L EE + H +P S H S+ + P Sbjct 207 HSPPSTKTPPANGAPPRVLQKLVEEDRIGRAHGGHPGSPRGSLSRHPSSQLAGPGVEGGE 266 Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109 D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I Sbjct 267 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 325 Query 110 ALILGILMTILLIVIPVLIFQ 130 AL+ G+L+ I VI + +++ Sbjct 326 ALVGGVLIIIASCVINLGVYK 346 >sp|Q9D103|IFM1_MOUSE Interferon-induced transmembrane protein 1 OS=Mus musculus OX=10090 GN=Ifitm1 PE=2 SV=1 Length=106 Score = 135 bits (339), Expect = 5e-41, Method: Composition-based stats. Identities = 70/103 (68%), Positives = 82/103 (80%), Gaps = 1/103 (1%) Query 22 MLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYS 81 M KE+ EV VLG+PH T+T I++ E S PDHVVWSLFNTLFMN CCLGF+A+AYS Sbjct 1 MPKEQQEVVVLGSPHISTSATATTINM-PEISTPDHVVWSLFNTLFMNFCCLGFVAYAYS 59 Query 82 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVI 124 VKSRDRKMVGD TGAQA+ASTAKCLNI +L IL I++IV+ Sbjct 60 VKSRDRKMVGDTTGAQAFASTAKCLNISSLFFTILTAIVVIVV 102 >sp|A6NMD0|IFM10_HUMAN Interferon-induced transmembrane protein 10 OS=Homo sapiens OX=9606 GN=IFITM10 PE=1 SV=1 Length=228 Score = 128 bits (321), Expect = 8e-37, Method: Composition-based stats. Identities = 43/125 (34%), Positives = 66/125 (53%), Gaps = 11/125 (9%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETS-VPDHVV 59 M S +G PP + L E+ + +TVI + +T+ V D+ + Sbjct 106 MESKSSKTDSVRAAGAPPACKHLAEKKTMTN----------PTTVIEVYPDTTEVNDYYL 155 Query 60 WSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTI 119 WS+FN +++N CCLGFIA AYS+K RD+K++ D+ GA A TA+ NI + L I Sbjct 156 WSIFNFVYLNFCCLGFIALAYSLKVRDKKLLNDLNGAVEDAKTARLFNITSSALAASCII 215 Query 120 LLIVI 124 L+ + Sbjct 216 LVFIF 220 >sp|Q8BR26|IFM10_MOUSE Interferon-induced transmembrane protein 10 OS=Mus musculus OX=10090 GN=Ifitm10 PE=2 SV=3 Length=201 Score = 121 bits (302), Expect = 3e-34, Method: Composition-based stats. Identities = 43/125 (34%), Positives = 65/125 (52%), Gaps = 11/125 (9%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETS-VPDHVV 59 M S SG P + L E+ + +TVI + +T+ V D+ + Sbjct 79 MESKSSKTDSVRASGVPQACKHLAEKKTMTN----------PTTVIEVYPDTTEVNDYYL 128 Query 60 WSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTI 119 WS+FN +++N CCLGFIA AYS+K RD+K++ D+ GA A TA+ NI + L I Sbjct 129 WSIFNFVYLNFCCLGFIALAYSLKVRDKKLLNDLNGAVEDAKTARLFNITSSALAASCII 188 Query 120 LLIVI 124 L+ + Sbjct 189 LIFIF 193 >sp|A6NNB3|IFM5_HUMAN Interferon-induced transmembrane protein 5 OS=Homo sapiens OX=9606 GN=IFITM5 PE=1 SV=1 Length=132 Score = 103 bits (256), Expect = 4e-28, Method: Composition-based stats. Identities = 39/86 (45%), Positives = 54/86 (63%), Gaps = 15/86 (17%) Query 27 HEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRD 86 H LGAPH P DH++WS+F+TL++N CCLGF+A AYS+K+RD Sbjct 21 HTALTLGAPHPPP---------------RDHLIWSVFSTLYLNLCCLGFLALAYSIKARD 65 Query 87 RKMVGDVTGAQAYASTAKCLNIWALI 112 +K+VGD+ A+ + S AKC NI A + Sbjct 66 QKVVGDLEAARRFGSKAKCYNILAAM 91 >sp|O88728|IFM5_MOUSE Interferon-induced transmembrane protein 5 OS=Mus musculus OX=10090 GN=Ifitm5 PE=1 SV=1 Length=134 Score = 100 bits (250), Expect = 3e-27, Method: Composition-based stats. Identities = 34/93 (37%), Positives = 55/93 (59%), Gaps = 9/93 (10%) Query 29 VAVLGAPHNPAPPTSTVIHIRSETSV---------PDHVVWSLFNTLFMNPCCLGFIAFA 79 + +P P+S + T++ DH++WS+F+T+++N CCLGF+A Sbjct 1 MDTSYPREDPRAPSSRKADAAAHTALSMGTPGPTPRDHMLWSVFSTMYLNLCCLGFLALV 60 Query 80 YSVKSRDRKMVGDVTGAQAYASTAKCLNIWALI 112 +SVK+RD+KM G++ A+ Y S AKC NI A + Sbjct 61 HSVKARDQKMAGNLEAARQYGSKAKCYNILAAM 93 >sp|Q91499|DSA2B_TORMA Dispanin subfamily A member 2b OS=Torpedo marmorata OX=7788 PE=2 SV=1 Length=107 Score = 96.7 bits (239), Expect = 6e-26, Method: Composition-based stats. Identities = 39/75 (52%), Positives = 48/75 (64%), Gaps = 1/75 (1%) Query 38 PAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQ 97 P P S V + DH+ WS+FN +MN CCLG A +SVKSRDRK+VGDV GA+ Sbjct 9 PMSPRS-VQGAPGTLPIRDHLPWSIFNLFYMNVCCLGLTAMIFSVKSRDRKVVGDVEGAR 67 Query 98 AYASTAKCLNIWALI 112 Y STA+ LNI A + Sbjct 68 HYGSTARSLNIAATV 82 >sp|Q6DFT4|TARG1_XENTR Trafficking regulator of GLUT4 1 OS=Xenopus tropicalis OX=8364 GN=trarg1 PE=2 SV=1 Length=179 Score = 62.1 bits (149), Expect = 1e-11, Method: Composition-based stats. Identities = 24/92 (26%), Positives = 50/92 (54%), Gaps = 2/92 (2%) Query 39 APPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQA 98 A +ST + + D++V ++F + F + +A +S+ SR+ GD+ GA+ Sbjct 90 ARASSTATTAQEQGRPTDYLVLAIF-SCFCPVWPVNIVALVFSIMSRNSLQQGDLDGARR 148 Query 99 YASTAKCLNIWALILGILMTILLIVIPVLIFQ 130 A+ L++ +++LG L+ I+L ++ + IF Sbjct 149 LGRLARLLSVVSILLG-LVIIVLCILSLTIFH 179 >sp|D3Z1U7|TM233_MOUSE Transmembrane protein 233 OS=Mus musculus OX=10090 GN=Tmem233 PE=1 SV=2 Length=110 Score = 50.5 bits (119), Expect = 7e-08, Method: Composition-based stats. Identities = 13/60 (22%), Positives = 25/60 (42%), Gaps = 0/60 (0%) Query 51 ETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWA 110 + P + +W + F + +A +S+ S + GD GA+ AK + I + Sbjct 31 DIPAPSNYLWLTIISCFCPAYPVNIVALVFSIMSLNSYNDGDYEGARRLGRNAKWVAIAS 90 >sp|B4DJY2|TM233_HUMAN Transmembrane protein 233 OS=Homo sapiens OX=9606 GN=TMEM233 PE=1 SV=1 Length=109 Score = 50.1 bits (118), Expect = 1e-07, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 25/59 (42%), Gaps = 0/59 (0%) Query 51 ETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109 + +P + +W + F + +A +S+ S + GD GA+ AK + I Sbjct 30 DVPMPKNYLWLTIVSCFCPAYPINIVALVFSIMSLNSYNDGDYEGARRLGRNAKWVAIA 88 >sp|A0A1B0GWB2|PRT1B_HUMAN Proline rich transmembrane protein 1B OS=Homo sapiens OX=9606 GN=PRRT1B PE=1 SV=1 Length=263 Score = 46.7 bits (109), Expect = 1e-05, Method: Composition-based stats. Identities = 33/126 (26%), Positives = 54/126 (43%), Gaps = 18/126 (14%) Query 4 TVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLF 63 T FSP P V P P +TV H D+++ S+ Sbjct 149 TPPALFSPPAGAAFP----------FPVYNGPMAGVPGPATVEHRPLP---KDYMMESVL 195 Query 64 NTLFMNPCCL--GFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILL 121 TLF CCL G IA YS ++R GD+ A+ + A+ L +++L+ G+ ++ Sbjct 196 VTLF---CCLLTGLIAIVYSHEARAALGRGDLAQAEEASRKARSLVLFSLLFGVFVSTSW 252 Query 122 IVIPVL 127 ++ V+ Sbjct 253 VIYVVV 258 >sp|Q2MHH0|TARG1_RAT Trafficking regulator of GLUT4 1 OS=Rattus norvegicus OX=10116 GN=Trarg1 PE=1 SV=1 Length=173 Score = 44.0 bits (102), Expect = 7e-05, Method: Composition-based stats. Identities = 11/51 (22%), Positives = 23/51 (45%), Gaps = 1/51 (2%) Query 44 TVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVT 94 T + + + + D++V ++ + F L I +S+ SR GD+ Sbjct 88 TTSYAQDQEAPKDYLVLAI-ASCFCPVWPLNLIPLIFSIMSRSSVQQGDLD 137 >sp|Q8C838|TARG1_MOUSE Trafficking regulator of GLUT4 1 OS=Mus musculus OX=10090 GN=Trarg1 PE=1 SV=1 Length=173 Score = 43.2 bits (100), Expect = 9e-05, Method: Composition-based stats. Identities = 11/51 (22%), Positives = 23/51 (45%), Gaps = 1/51 (2%) Query 44 TVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVT 94 T + + + + D++V ++ + F L I +S+ SR GD+ Sbjct 88 TTSYAQDQEAPKDYLVLAI-ASCFCPVWPLNLIPLIFSIMSRSSVQQGDLD 137 >sp|Q6MG82|PRRT1_RAT Proline-rich transmembrane protein 1 OS=Rattus norvegicus OX=10116 GN=Prrt1 PE=1 SV=2 Length=306 Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 18/76 (24%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Query 56 DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI 115 D++ ++ T+ G IA +V+ R GD+ A+ + A+ + +L +GI Sbjct 222 DYMPIAVLTTICC-FWPTGIIAIFKAVQVRTALARGDLVSAEIASREARNFSFISLAVGI 280 Query 116 LMTILLIVIPVLIFQA 131 +L ++ V+I A Sbjct 281 AAMVLCTILTVVIIIA 296 >sp|O35449|PRRT1_MOUSE Proline-rich transmembrane protein 1 OS=Mus musculus OX=10090 GN=Prrt1 PE=1 SV=1 Length=306 Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 18/76 (24%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Query 56 DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI 115 D++ ++ T+ G IA +V+ R GD+ A+ + A+ + +L +GI Sbjct 222 DYMPIAVLTTICC-FWPTGIIAIFKAVQVRTALARGDLVSAEIASREARNFSFISLAVGI 280 Query 116 LMTILLIVIPVLIFQA 131 +L ++ V+I A Sbjct 281 AAMVLCTILTVVIIIA 296 >sp|Q8IXB3|TARG1_HUMAN Trafficking regulator of GLUT4 1 OS=Homo sapiens OX=9606 GN=TRARG1 PE=1 SV=2 Length=177 Score = 40.9 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 22/52 (42%), Gaps = 1/52 (2%) Query 43 STVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVT 94 +T + + + + D+++ ++ F L I S+ SR G+V Sbjct 90 ATTSYAQDQEAPRDYLILAVV-ACFCPVWPLNLIPLIISIMSRSSMQQGNVD 140 >sp|Q99946|PRRT1_HUMAN Proline-rich transmembrane protein 1 OS=Homo sapiens OX=9606 GN=PRRT1 PE=1 SV=2 Length=306 Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 18/76 (24%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Query 56 DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI 115 D++ ++ T+ G IA +V+ R GD+ A+ + A+ + +L +GI Sbjct 222 DYMPIAVLTTICC-FWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGI 280 Query 116 LMTILLIVIPVLIFQA 131 +L ++ V+I A Sbjct 281 AAMVLCTILTVVIIIA 296 >sp|Q8C581|TMM91_MOUSE Transmembrane protein 91 OS=Mus musculus OX=10090 GN=Tmem91 PE=2 SV=1 Length=172 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 22/76 (29%), Positives = 36/76 (47%), Gaps = 2/76 (3%) Query 56 DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI 115 DH+ ++F+ L +G AF + K+ GDV GA A + A L + A+ LG Sbjct 94 DHLGLAVFSVLCC-FWPVGIAAFCLAHKTNKAWAKGDVQGAGAASRRAFLLGVLAVGLG- 151 Query 116 LMTILLIVIPVLIFQA 131 L T ++ + + A Sbjct 152 LCTYAAALVTLAAYLA 167 >sp|Q6ZNR0|TMM91_HUMAN Transmembrane protein 91 OS=Homo sapiens OX=9606 GN=TMEM91 PE=1 SV=1 Length=172 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 2/76 (3%) Query 56 DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI 115 DH+ ++F+ L +G AF + K+ GD+ GA A + A L + A+ LG+ Sbjct 94 DHLGLAVFSMLCC-FWPVGIAAFCLAQKTNKAWAKGDIQGAGAASRRAFLLGVLAVGLGV 152 Query 116 LMTILLIVIPVLIFQA 131 T ++ + + A Sbjct 153 -CTYAAALVTLAAYLA 167 >sp|Q4R532|SYNG1_MACFA Synapse differentiation-inducing gene protein 1 OS=Macaca fascicularis OX=9541 GN=SYNDIG1 PE=2 SV=1 Length=258 Score = 35.9 bits (81), Expect = 0.061, Method: Composition-based stats. Identities = 17/72 (24%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILG 114 DH+ S+F+ L LG AF S ++ GD+ A + A L + ++ +G Sbjct 179 RDHLGLSVFSMLCC-FWPLGIAAFYLSHETNKAVAKGDLHQASTSSRRALFLAVLSITIG 237 Query 115 ILMTILLIVIPV 126 + + + V + Sbjct 238 TGVYVGVAVALI 249 >sp|Q6NFU3|TIG_CORDI Trigger factor OS=Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis) OX=257309 GN=tig PE=3 SV=1 Length=448 Score = 35.9 bits (81), Expect = 0.066, Method: Composition-based stats. Identities = 17/59 (29%), Positives = 29/59 (49%), Gaps = 8/59 (14%) Query 12 VNSGQPPNYEMLKEEHEVAVLGAPH--------NPAPPTSTVIHIRSETSVPDHVVWSL 62 +N P Y+ + EE+E+ VLG PH N + + +R E +VPD +++ Sbjct 68 INDMLPTRYQQVVEENELVVLGQPHIDITKLEDNEVVEFTAEVDVRPEITVPDFSAFAV 126 >sp|Q9H7V2|SYNG1_HUMAN Synapse differentiation-inducing gene protein 1 OS=Homo sapiens OX=9606 GN=SYNDIG1 PE=1 SV=1 Length=258 Score = 35.5 bits (80), Expect = 0.067, Method: Composition-based stats. Identities = 17/72 (24%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILG 114 DH+ S+F+ L LG AF S ++ GD+ A + A L + ++ +G Sbjct 179 RDHLGLSVFSMLCC-FWPLGIAAFYLSHETNKAVAKGDLHQASTSSRRALFLAVLSITIG 237 Query 115 ILMTILLIVIPV 126 + + + V + Sbjct 238 TGVYVGVAVALI 249 >sp|Q58DZ9|SYNG1_RAT Synapse differentiation-inducing gene protein 1 OS=Rattus norvegicus OX=10116 GN=Syndig1 PE=1 SV=1 Length=258 Score = 35.1 bits (79), Expect = 0.097, Method: Composition-based stats. Identities = 17/72 (24%), Positives = 31/72 (43%), Gaps = 1/72 (1%) Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILG 114 DH+ S+F+ L LG AF S ++ GD A + A L + ++ +G Sbjct 179 RDHLGLSVFSMLCC-FWPLGIAAFYLSHETNKAVAKGDFHQASTSSRRALFLAVLSITIG 237 Query 115 ILMTILLIVIPV 126 + + + V + Sbjct 238 TGIYVGVAVALI 249 >sp|A2ANU3|SYNG1_MOUSE Synapse differentiation-inducing gene protein 1 OS=Mus musculus OX=10090 GN=Syndig1 PE=1 SV=1 Length=258 Score = 35.1 bits (79), Expect = 0.10, Method: Composition-based stats. Identities = 17/72 (24%), Positives = 31/72 (43%), Gaps = 1/72 (1%) Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILG 114 DH+ S+F+ L LG AF S ++ GD A + A L + ++ +G Sbjct 179 RDHLGLSVFSMLCC-FWPLGIAAFYLSHETNKAVAKGDFHQASTSSRRALFLAVLSITIG 237 Query 115 ILMTILLIVIPV 126 + + + V + Sbjct 238 TGIYVGVAVALI 249 >sp|Q08DM6|SYNG1_BOVIN Synapse differentiation-inducing gene protein 1 OS=Bos taurus OX=9913 GN=SYNDIG1 PE=2 SV=1 Length=258 Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats. Identities = 17/72 (24%), Positives = 31/72 (43%), Gaps = 1/72 (1%) Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILG 114 DH+ S+F+ L LG AF S ++ GD A + A L + ++ +G Sbjct 179 RDHLGLSVFSMLCC-FWPLGIAAFYLSHETNKAVAKGDFHQASTSSRRALFLAVLSITIG 237 Query 115 ILMTILLIVIPV 126 + + + V + Sbjct 238 TGIYVGVAVALI 249 >sp|A4IFJ1|SYN1L_BOVIN Synapse differentiation-inducing gene protein 1-like OS=Bos taurus OX=9913 GN=SYNDIG1L PE=2 SV=1 Length=238 Score = 32.4 bits (72), Expect = 0.99, Method: Composition-based stats. Identities = 19/96 (20%), Positives = 35/96 (36%), Gaps = 5/96 (5%) Query 24 KEEHEVAVLGAPHNPAPPTSTVIHIRSE--TSVP--DHVVWSLFNTLFMNPCCLGFIAFA 79 +E G P ++ + ++P DH+ ++F+ L LG AF Sbjct 124 VQEEFQGQEGDPEEEESDATSTESESEDNFLTLPPRDHLGLTIFSMLCC-FWPLGIAAFY 182 Query 80 YSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI 115 +S + GD A + A L ++ +G Sbjct 183 FSQGTSKAISKGDFRLANTTSRRALFLATLSIAVGA 218 >sp|Q3USQ7|SYN1L_MOUSE Synapse differentiation-inducing gene protein 1-like OS=Mus musculus OX=10090 GN=Syndig1l PE=2 SV=1 Length=237 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 27/80 (34%), Gaps = 1/80 (1%) Query 36 HNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTG 95 + S DH+ +LF+ L LG AF +S + GD Sbjct 139 SDGTSSESECEDAFLTLPPRDHLGLTLFSMLCC-FWPLGIAAFYFSQGTSKAISKGDFRL 197 Query 96 AQAYASTAKCLNIWALILGI 115 A + A L ++ +G Sbjct 198 ASTTSRRALFLATLSIAVGA 217 >sp|P11947|COX1_TETPY Cytochrome c oxidase subunit 1 OS=Tetrahymena pyriformis OX=5908 GN=COI PE=3 SV=1 Length=698 Score = 32.0 bits (71), Expect = 1.4, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 46/128 (36%), Gaps = 4/128 (3%) Query 3 HTVQTFFSPVNSGQPPNYEMLK---EEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVV 59 H TFF G P + L EV VL P + + H++ Sbjct 375 HWQTTFFEYAYGGDPILSQHLFWFFGHPEVYVLIIPTFGFINMIVPHNNTRRVASKHHMI 434 Query 60 WSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLN-IWALILGILMT 118 W+++ +M G + + R R M +T + +T K +N +L+ G L Sbjct 435 WAIYVMAYMGYLVWGHHMYLVGLDHRSRTMYSTITIMISMPATIKVVNWTLSLVNGALKV 494 Query 119 ILLIVIPV 126 L + + Sbjct 495 DLPFLFSM 502 >sp|A6NDD5|SYN1L_HUMAN Synapse differentiation-inducing gene protein 1-like OS=Homo sapiens OX=9606 GN=SYNDIG1L PE=3 SV=1 Length=238 Score = 31.6 bits (70), Expect = 1.7, Method: Composition-based stats. Identities = 17/61 (28%), Positives = 25/61 (41%), Gaps = 1/61 (2%) Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILG 114 DH+ +LF+ L LG AF +S + GD A + A L A+ +G Sbjct 159 RDHLGLTLFSMLCC-FWPLGIAAFYFSQGTSKAISKGDFRLASTTSRRALFLATLAIAVG 217 Query 115 I 115 Sbjct 218 A 218 >sp|P05489|COX1_PARTE Cytochrome c oxidase subunit 1 OS=Paramecium tetraurelia OX=5888 GN=COI PE=3 SV=1 Length=645 Score = 31.6 bits (70), Expect = 2.2, Method: Composition-based stats. Identities = 25/128 (20%), Positives = 44/128 (34%), Gaps = 4/128 (3%) Query 3 HTVQTFFSPVNSGQPPNYEMLK---EEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVV 59 H +FF G P ++ L EV +L P + S H++ Sbjct 317 HWQTSFFDFAYGGDPILFQHLFWFFGHPEVYILIIPSFGVANIVLPFYTMRRMSSKHHMI 376 Query 60 WSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTI 119 W+++ +M G + + R R + +T +T K +N W L L Sbjct 377 WAVYVMAYMGFVVWGHHMYLVGLDHRSRNIYSTITIMICLPATIKLVN-WTLTLANAAIH 435 Query 120 LLIVIPVL 127 + +V Sbjct 436 VDLVFLFF 443 >sp|A0A396JU32|ENOD2_MEDTR Early nodule-specific protein 2 OS=Medicago truncatula OX=3880 GN=ENOD2 PE=2 SV=1 Length=593 Score = 30.9 bits (68), Expect = 3.6, Method: Composition-based stats. Identities = 11/40 (28%), Positives = 16/40 (40%), Gaps = 0/40 (0%) Query 2 NHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPP 41 + F+P + PPNY + E + PH PP Sbjct 485 HENPPPEFAPPHKKLPPNYNPPRHEKPMPKYQPPHEKLPP 524 >sp|Q16643|DREB_HUMAN Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1 SV=4 Length=649 Score = 30.9 bits (68), Expect = 4.0, Method: Composition-based stats. Identities = 19/52 (37%), Positives = 22/52 (42%), Gaps = 0/52 (0%) Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSET 52 M Q P G P M E E AVL AP PA +T IH ++T Sbjct 401 MEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDAADT 452 >sp|P49796|RGS3_HUMAN Regulator of G-protein signaling 3 OS=Homo sapiens OX=9606 GN=RGS3 PE=1 SV=2 Length=1198 Score = 30.9 bits (68), Expect = 4.1, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 15/47 (32%), Gaps = 0/47 (0%) Query 5 VQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSE 51 SP P+ E L + G+P P P S + E Sbjct 723 PPNKDSPSGQEPAPSQEPLSSKDSATSEGSPPGPDAPPSKDVPPCQE 769 >sp|Q66HA5|C2D1A_RAT Coiled-coil and C2 domain-containing protein 1A OS=Rattus norvegicus OX=10116 GN=Cc2d1a PE=1 SV=2 Length=941 Score = 30.1 bits (66), Expect = 6.1, Method: Composition-based stats. Identities = 21/97 (22%), Positives = 30/97 (31%), Gaps = 2/97 (2%) Query 11 PVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNP 70 PV SG+ P H + L PAP S + S T+ + Sbjct 192 PVASGKGPAIGH-SHTHTTSHLAPVSPPAPEPSVTLEAPSTTAQTSAKPQLSPDPC-SPL 249 Query 71 CCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLN 107 L + Y V + K D A Y +K + Sbjct 250 ARLQSLQHEYKVAALRAKHQDDTATAARYLRVSKSFD 286 >sp|P10637|TAU_MOUSE Microtubule-associated protein tau OS=Mus musculus OX=10090 GN=Mapt PE=1 SV=3 Length=733 Score = 30.1 bits (66), Expect = 6.8, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 20/55 (36%), Gaps = 3/55 (5%) Query 4 TVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHV 58 T + +P SG+PP E + G+P P + T T P V Sbjct 467 TTPSPKTPPGSGEPPKS---GERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKV 518 >sp|P19332|TAU_RAT Microtubule-associated protein tau OS=Rattus norvegicus OX=10116 GN=Mapt PE=1 SV=3 Length=752 Score = 29.7 bits (65), Expect = 8.3, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 20/55 (36%), Gaps = 3/55 (5%) Query 4 TVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHV 58 T + +P SG+PP E + G+P P + T T P V Sbjct 486 TTPSPKTPPGSGEPPKS---GERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKV 537 >sp|Q5TZE2|SYN1L_DANRE Synapse differentiation-inducing gene protein 1-like OS=Danio rerio OX=7955 GN=syndig1l PE=3 SV=1 Length=258 Score = 29.3 bits (64), Expect = 9.7, Method: Composition-based stats. Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 1/57 (2%) Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWAL 111 DH+ ++F+ L LG AF +S + GD A + A L ++ Sbjct 179 RDHLGLAIFSMLCC-FWPLGIAAFYFSQGTSKAVTKGDFPLASIASRRALFLAALSI 234 Lambda K H a alpha 0.317 0.125 0.330 0.792 4.96 Gapped Lambda K H a alpha sigma 0.267 0.0384 0.140 1.90 42.6 43.6 Effective search space used: 5113651884 Database: uniprot_sprot.fasta Posted date: Aug 1, 2024 3:29 PM Number of letters in database: 207,016,062 Number of sequences in database: 571,864 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40