PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
571,864 sequences; 207,016,062 total letters
Results from round 1
Query= sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein 3
OS=Homo sapiens OX=9606 GN=IFITM3 PE=1 SV=2
Length=133
Score E
Sequences producing significant alignments: (Bits) Value
sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein 3 O... 278 4e-97
sp|Q01629|IFM2_HUMAN Interferon-induced transmembrane protein 2 O... 248 2e-85
sp|C9JQL5|DSA2D_HUMAN Putative dispanin subfamily A member 2d OS=... 224 7e-76
sp|Q9CQW9|IFM3_MOUSE Interferon-induced transmembrane protein 3 O... 186 8e-61
sp|P26376|IFM3_RAT Interferon-induced transmembrane protein 3 OS=... 184 5e-60
sp|P13164|IFM1_HUMAN Interferon-induced transmembrane protein 1 O... 176 8e-57
sp|Q99J93|IFM2_MOUSE Interferon-induced transmembrane protein 2 O... 167 3e-53
sp|Q9D103|IFM1_MOUSE Interferon-induced transmembrane protein 1 O... 144 1e-44
sp|A6NNB3|IFM5_HUMAN Interferon-induced transmembrane protein 5 O... 84.0 1e-20
sp|Q91499|DSA2B_TORMA Dispanin subfamily A member 2b OS=Torpedo m... 81.3 9e-20
sp|O88728|IFM5_MOUSE Interferon-induced transmembrane protein 5 O... 76.6 1e-17
sp|A6NMD0|IFM10_HUMAN Interferon-induced transmembrane protein 10... 75.9 2e-16
sp|Q8BR26|IFM10_MOUSE Interferon-induced transmembrane protein 10... 74.3 4e-16
sp|Q5RAC1|PRRT2_PONAB Proline-rich transmembrane protein 2 OS=Pon... 49.7 1e-06
sp|D3ZFB6|PRRT2_RAT Proline-rich transmembrane protein 2 OS=Rattu... 48.9 2e-06
sp|Q7Z6L0|PRRT2_HUMAN Proline-rich transmembrane protein 2 OS=Hom... 48.5 3e-06
sp|E9PUL5|PRRT2_MOUSE Proline-rich transmembrane protein 2 OS=Mus... 48.5 3e-06
sp|A0A1B0GWB2|PRT1B_HUMAN Proline rich transmembrane protein 1B O... 38.9 0.005
sp|Q6NFU3|TIG_CORDI Trigger factor OS=Corynebacterium diphtheriae... 33.9 0.28
sp|Q6ZNR0|TMM91_HUMAN Transmembrane protein 91 OS=Homo sapiens OX... 31.2 1.7
sp|Q5E9S8|CDIN1_BOVIN CDAN1-interacting nuclease 1 OS=Bos taurus ... 31.6 1.7
sp|Q16643|DREB_HUMAN Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1... 31.6 2.0
sp|Q8C581|TMM91_MOUSE Transmembrane protein 91 OS=Mus musculus OX... 30.8 2.7
sp|Q3U4G0|CDIN1_MOUSE CDAN1-interacting nuclease 1 OS=Mus musculu... 30.0 5.9
sp|Q97CM5|DTDA_THEVO D-aminoacyl-tRNA deacylase OS=Thermoplasma v... 30.0 6.7
sp|Q4JQW3|TEG1_VZVO Tegument protein UL46 homolog OS=Varicella-zo... 30.0 7.0
sp|P09264|TEG1_VZVD Tegument protein UL46 homolog OS=Varicella-zo... 30.0 7.0
sp|O22920|CHX13_ARATH Cation/H(+) symporter 13 OS=Arabidopsis tha... 30.0 7.3
sp|Q9Y2V0|CDIN1_HUMAN CDAN1-interacting nuclease 1 OS=Homo sapien... 29.6 8.9
sp|Q8LPL3|ASO_ARATH L-ascorbate oxidase OS=Arabidopsis thaliana O... 29.6 9.0
sp|O15018|PDZD2_HUMAN PDZ domain-containing protein 2 OS=Homo sap... 29.6 9.1
>sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein
3 OS=Homo sapiens OX=9606 GN=IFITM3 PE=1 SV=2
Length=133
Score = 278 bits (710), Expect = 4e-97, Method: Compositional matrix adjust.
Identities = 133/133 (100%), Positives = 133/133 (100%), Gaps = 0/133 (0%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW
Sbjct 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120
SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL
Sbjct 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120
Query 121 LIVIPVLIFQAYG 133
LIVIPVLIFQAYG
Sbjct 121 LIVIPVLIFQAYG 133
>sp|Q01629|IFM2_HUMAN Interferon-induced transmembrane protein
2 OS=Homo sapiens OX=9606 GN=IFITM2 PE=1 SV=2
Length=132
Score = 248 bits (633), Expect = 2e-85, Method: Compositional matrix adjust.
Identities = 120/131 (92%), Positives = 123/131 (94%), Gaps = 1/131 (1%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
MNH VQTF SPVNSGQPPNYEMLKEE EVA+LG PHNPAPP STVIHIRSETSVPDHVVW
Sbjct 1 MNHIVQTF-SPVNSGQPPNYEMLKEEQEVAMLGVPHNPAPPMSTVIHIRSETSVPDHVVW 59
Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120
SLFNTLFMN CCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI MTIL
Sbjct 60 SLFNTLFMNTCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGIFMTIL 119
Query 121 LIVIPVLIFQA 131
LI+IPVL+ QA
Sbjct 120 LIIIPVLVVQA 130
>sp|C9JQL5|DSA2D_HUMAN Putative dispanin subfamily A member 2d
OS=Homo sapiens OX=9606 PE=5 SV=1
Length=133
Score = 224 bits (570), Expect = 7e-76, Method: Compositional matrix adjust.
Identities = 124/132 (94%), Positives = 129/132 (98%), Gaps = 0/132 (0%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
MNHTVQTFFSPVNSGQPPNYEMLKEEH+VAVLG PHNPAPPTSTVIHIRS+TSVP HVVW
Sbjct 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHKVAVLGVPHNPAPPTSTVIHIRSKTSVPHHVVW 60
Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120
SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVG+VTGAQAYAST KCLNIWALILGILMTIL
Sbjct 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGNVTGAQAYASTTKCLNIWALILGILMTIL 120
Query 121 LIVIPVLIFQAY 132
LI+IPVLIFQA+
Sbjct 121 LIIIPVLIFQAH 132
>sp|Q9CQW9|IFM3_MOUSE Interferon-induced transmembrane protein
3 OS=Mus musculus OX=10090 GN=Ifitm3 PE=1 SV=1
Length=137
Score = 186 bits (472), Expect = 8e-61, Method: Compositional matrix adjust.
Identities = 87/117 (74%), Positives = 97/117 (83%), Gaps = 0/117 (0%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
MNHT Q F + + GQPPNYE +KEE+EVA +GAPH A +TVI++ E SVPDHVVW
Sbjct 1 MNHTSQAFITAASGGQPPNYERIKEEYEVAEMGAPHGSASVRTTVINMPREVSVPDHVVW 60
Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILM 117
SLFNTLFMN CCLGFIA+AYSVKSRDRKMVGDVTGAQAYASTAKCLNI L+L ILM
Sbjct 61 SLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDVTGAQAYASTAKCLNISTLVLSILM 117
>sp|P26376|IFM3_RAT Interferon-induced transmembrane protein 3
OS=Rattus norvegicus OX=10116 GN=ifitm3 PE=2 SV=1
Length=137
Score = 184 bits (467), Expect = 5e-60, Method: Compositional matrix adjust.
Identities = 86/117 (74%), Positives = 97/117 (83%), Gaps = 0/117 (0%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
MNHT Q F + GQPPNYE +KEE+EV+ LGAPH A +TVI++ E SVPDHVVW
Sbjct 1 MNHTSQAFVNAATGGQPPNYERIKEEYEVSELGAPHGSASVRTTVINMPREVSVPDHVVW 60
Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILM 117
SLFNTLFMN CCLGFIA+AYSVKSRDRKMVGD+TGAQAYASTAKCLNI +L+L ILM
Sbjct 61 SLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDMTGAQAYASTAKCLNISSLVLSILM 117
>sp|P13164|IFM1_HUMAN Interferon-induced transmembrane protein
1 OS=Homo sapiens OX=9606 GN=IFITM1 PE=1 SV=3
Length=125
Score = 176 bits (445), Expect = 8e-57, Method: Compositional matrix adjust.
Identities = 88/106 (83%), Positives = 93/106 (88%), Gaps = 0/106 (0%)
Query 22 MLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYS 81
M KEEHEVAVLG P + P STVI+I SETSVPDHVVWSLFNTLF+N CCLGFIAFAYS
Sbjct 1 MHKEEHEVAVLGPPPSTILPRSTVINIHSETSVPDHVVWSLFNTLFLNWCCLGFIAFAYS 60
Query 82 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVIPVL 127
VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTI I++ V
Sbjct 61 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIGFILLLVF 106
>sp|Q99J93|IFM2_MOUSE Interferon-induced transmembrane protein
2 OS=Mus musculus OX=10090 GN=Ifitm2 PE=1 SV=1
Length=144
Score = 167 bits (422), Expect = 3e-53, Method: Compositional matrix adjust.
Identities = 84/137 (61%), Positives = 100/137 (73%), Gaps = 5/137 (4%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
M+H Q F S N+G PP+YE +KEE+ V LG P N A +TVI++ E SVPDHVVW
Sbjct 1 MSHNSQAFLS-TNAGLPPSYETIKEEYGVTELGEPSNSAVVRTTVINMPREVSVPDHVVW 59
Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILM--- 117
SLFNTLF N CCLGF+A+AYSVKSRDRKMVGDV GAQAYASTAKCLNI +LI ILM
Sbjct 60 SLFNTLFFNACCLGFVAYAYSVKSRDRKMVGDVVGAQAYASTAKCLNISSLIFSILMVII 119
Query 118 -TILLIVIPVLIFQAYG 133
I+ V++FQ++
Sbjct 120 CIIIFSTTSVVVFQSFA 136
>sp|Q9D103|IFM1_MOUSE Interferon-induced transmembrane protein
1 OS=Mus musculus OX=10090 GN=Ifitm1 PE=2 SV=1
Length=106
Score = 144 bits (363), Expect = 1e-44, Method: Compositional matrix adjust.
Identities = 70/103 (68%), Positives = 82/103 (80%), Gaps = 1/103 (1%)
Query 22 MLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYS 81
M KE+ EV VLG+PH T+T I++ E S PDHVVWSLFNTLFMN CCLGF+A+AYS
Sbjct 1 MPKEQQEVVVLGSPHISTSATATTINM-PEISTPDHVVWSLFNTLFMNFCCLGFVAYAYS 59
Query 82 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVI 124
VKSRDRKMVGD TGAQA+ASTAKCLNI +L IL I++IV+
Sbjct 60 VKSRDRKMVGDTTGAQAFASTAKCLNISSLFFTILTAIVVIVV 102
>sp|A6NNB3|IFM5_HUMAN Interferon-induced transmembrane protein
5 OS=Homo sapiens OX=9606 GN=IFITM5 PE=1 SV=1
Length=132
Score = 84.0 bits (206), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 40/86 (47%), Positives = 55/86 (64%), Gaps = 15/86 (17%)
Query 27 HEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRD 86
H LGAPH PP DH++WS+F+TL++N CCLGF+A AYS+K+RD
Sbjct 21 HTALTLGAPH---PPPR------------DHLIWSVFSTLYLNLCCLGFLALAYSIKARD 65
Query 87 RKMVGDVTGAQAYASTAKCLNIWALI 112
+K+VGD+ A+ + S AKC NI A +
Sbjct 66 QKVVGDLEAARRFGSKAKCYNILAAM 91
>sp|Q91499|DSA2B_TORMA Dispanin subfamily A member 2b OS=Torpedo
marmorata OX=7788 PE=2 SV=1
Length=107
Score = 81.3 bits (199), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 35/59 (59%), Positives = 44/59 (75%), Gaps = 0/59 (0%)
Query 54 VPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALI 112
+ DH+ WS+FN +MN CCLG A +SVKSRDRK+VGDV GA+ Y STA+ LNI A +
Sbjct 24 IRDHLPWSIFNLFYMNVCCLGLTAMIFSVKSRDRKVVGDVEGARHYGSTARSLNIAATV 82
>sp|O88728|IFM5_MOUSE Interferon-induced transmembrane protein
5 OS=Mus musculus OX=10090 GN=Ifitm5 PE=1 SV=1
Length=134
Score = 76.6 bits (187), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 34/86 (40%), Positives = 54/86 (63%), Gaps = 9/86 (10%)
Query 36 HNPAPPTSTVIHIRSETSVP---------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRD 86
+P P+S + T++ DH++WS+F+T+++N CCLGF+A +SVK+RD
Sbjct 8 EDPRAPSSRKADAAAHTALSMGTPGPTPRDHMLWSVFSTMYLNLCCLGFLALVHSVKARD 67
Query 87 RKMVGDVTGAQAYASTAKCLNIWALI 112
+KM G++ A+ Y S AKC NI A +
Sbjct 68 QKMAGNLEAARQYGSKAKCYNILAAM 93
>sp|A6NMD0|IFM10_HUMAN Interferon-induced transmembrane protein
10 OS=Homo sapiens OX=9606 GN=IFITM10 PE=1 SV=1
Length=228
Score = 75.9 bits (185), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 43/112 (38%), Positives = 66/112 (59%), Gaps = 11/112 (10%)
Query 14 SGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETS-VPDHVVWSLFNTLFMNPCC 72
+G PP + L E+ + NP +TVI + +T+ V D+ +WS+FN +++N CC
Sbjct 119 AGAPPACKHLAEKKTMT------NP----TTVIEVYPDTTEVNDYYLWSIFNFVYLNFCC 168
Query 73 LGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVI 124
LGFIA AYS+K RD+K++ D+ GA A TA+ NI + L IL+ +
Sbjct 169 LGFIALAYSLKVRDKKLLNDLNGAVEDAKTARLFNITSSALAASCIILVFIF 220
>sp|Q8BR26|IFM10_MOUSE Interferon-induced transmembrane protein
10 OS=Mus musculus OX=10090 GN=Ifitm10 PE=2 SV=3
Length=201
Score = 74.3 bits (181), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 36/83 (43%), Positives = 55/83 (66%), Gaps = 1/83 (1%)
Query 43 STVIHIRSETS-VPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYAS 101
+TVI + +T+ V D+ +WS+FN +++N CCLGFIA AYS+K RD+K++ D+ GA A
Sbjct 111 TTVIEVYPDTTEVNDYYLWSIFNFVYLNFCCLGFIALAYSLKVRDKKLLNDLNGAVEDAK 170
Query 102 TAKCLNIWALILGILMTILLIVI 124
TA+ NI + L IL+ +
Sbjct 171 TARLFNITSSALAASCIILIFIF 193
>sp|Q5RAC1|PRRT2_PONAB Proline-rich transmembrane protein 2 OS=Pongo
abelii OX=9601 GN=PRRT2 PE=2 SV=1
Length=340
Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 14/141 (10%)
Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55
H+ + SP +G PP + L EE + + H +P S H S+ + P
Sbjct 201 HSPPSKKSPPANGAPPRVLQQLVEEDRMGRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGE 260
Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109
D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I
Sbjct 261 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 319
Query 110 ALILGILMTILLIVIPVLIFQ 130
AL+ G+L+ I VI + +++
Sbjct 320 ALVGGVLIIIASCVINLGVYK 340
>sp|D3ZFB6|PRRT2_RAT Proline-rich transmembrane protein 2 OS=Rattus
norvegicus OX=10116 GN=Prrt2 PE=1 SV=1
Length=344
Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 67/141 (48%), Gaps = 14/141 (10%)
Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55
H+ + +P +G PP + L EE + H +P S H S+ + P
Sbjct 205 HSPPSTKTPPANGAPPRVLQKLVEEDRIGRAHGGHPGSPRGSLSRHPSSQLAGPGVEGGE 264
Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109
D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I
Sbjct 265 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 323
Query 110 ALILGILMTILLIVIPVLIFQ 130
AL+ G+L+ I VI + +++
Sbjct 324 ALVGGVLIIIASCVINLGVYK 344
>sp|Q7Z6L0|PRRT2_HUMAN Proline-rich transmembrane protein 2 OS=Homo
sapiens OX=9606 GN=PRRT2 PE=1 SV=1
Length=340
Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 14/141 (10%)
Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55
H+ + SP +G PP + L EE + + H +P S H S+ + P
Sbjct 201 HSPPSKKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGE 260
Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109
D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I
Sbjct 261 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 319
Query 110 ALILGILMTILLIVIPVLIFQ 130
AL+ G+L+ I VI + +++
Sbjct 320 ALVGGVLIIIASCVINLGVYK 340
>sp|E9PUL5|PRRT2_MOUSE Proline-rich transmembrane protein 2 OS=Mus
musculus OX=10090 GN=Prrt2 PE=1 SV=1
Length=346
Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 67/141 (48%), Gaps = 14/141 (10%)
Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55
H+ + +P +G PP + L EE + H +P S H S+ + P
Sbjct 207 HSPPSTKTPPANGAPPRVLQKLVEEDRIGRAHGGHPGSPRGSLSRHPSSQLAGPGVEGGE 266
Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109
D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I
Sbjct 267 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 325
Query 110 ALILGILMTILLIVIPVLIFQ 130
AL+ G+L+ I VI + +++
Sbjct 326 ALVGGVLIIIASCVINLGVYK 346
>sp|A0A1B0GWB2|PRT1B_HUMAN Proline rich transmembrane protein
1B OS=Homo sapiens OX=9606 GN=PRRT1B PE=1 SV=1
Length=263
Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 21/70 (30%), Positives = 40/70 (57%), Gaps = 5/70 (7%)
Query 56 DHVVWSLFNTLFMNPCCL--GFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALIL 113
D+++ S+ TLF CCL G IA YS ++R GD+ A+ + A+ L +++L+
Sbjct 188 DYMMESVLVTLF---CCLLTGLIAIVYSHEARAALGRGDLAQAEEASRKARSLVLFSLLF 244
Query 114 GILMTILLIV 123
G+ ++ ++
Sbjct 245 GVFVSTSWVI 254
>sp|Q6NFU3|TIG_CORDI Trigger factor OS=Corynebacterium diphtheriae
(strain ATCC 700971 / NCTC 13129 / Biotype gravis) OX=257309
GN=tig PE=3 SV=1
Length=448
Score = 33.9 bits (76), Expect = 0.28, Method: Composition-based stats.
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 8/53 (15%)
Query 12 VNSGQPPNYEMLKEEHEVAVLGAPH--------NPAPPTSTVIHIRSETSVPD 56
+N P Y+ + EE+E+ VLG PH N + + +R E +VPD
Sbjct 68 INDMLPTRYQQVVEENELVVLGQPHIDITKLEDNEVVEFTAEVDVRPEITVPD 120
>sp|Q6ZNR0|TMM91_HUMAN Transmembrane protein 91 OS=Homo sapiens
OX=9606 GN=TMEM91 PE=1 SV=1
Length=172
Score = 31.2 bits (69), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 20/63 (32%), Positives = 32/63 (51%), Gaps = 7/63 (11%)
Query 56 DHVVWSLFNTLFMNPCC---LGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALI 112
DH+ ++F+ L CC +G AF + K+ GD+ GA A + A L + A+
Sbjct 94 DHLGLAVFSML----CCFWPVGIAAFCLAQKTNKAWAKGDIQGAGAASRRAFLLGVLAVG 149
Query 113 LGI 115
LG+
Sbjct 150 LGV 152
>sp|Q5E9S8|CDIN1_BOVIN CDAN1-interacting nuclease 1 OS=Bos taurus
OX=9913 GN=CDIN1 PE=2 SV=1
Length=281
Score = 31.6 bits (70), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 2/41 (5%)
Query 36 HNPAPPTSTVIH--IRSETSVPDHVVWSLFNTLFMNPCCLG 74
H APP+ +VI+ +R + +PD V+ + +N CC G
Sbjct 111 HEEAPPSKSVINSMLRDPSQIPDGVLANQVYQCIVNDCCYG 151
>sp|Q16643|DREB_HUMAN Drebrin OS=Homo sapiens OX=9606 GN=DBN1
PE=1 SV=4
Length=649
Score = 31.6 bits (70), Expect = 2.0, Method: Composition-based stats.
Identities = 19/52 (37%), Positives = 22/52 (42%), Gaps = 0/52 (0%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSET 52
M Q P G P M E E AVL AP PA +T IH ++T
Sbjct 401 MEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDAADT 452
>sp|Q8C581|TMM91_MOUSE Transmembrane protein 91 OS=Mus musculus
OX=10090 GN=Tmem91 PE=2 SV=1
Length=172
Score = 30.8 bits (68), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 21/63 (33%), Positives = 32/63 (51%), Gaps = 7/63 (11%)
Query 56 DHVVWSLFNTLFMNPCC---LGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALI 112
DH+ ++F+ L CC +G AF + K+ GDV GA A + A L + A+
Sbjct 94 DHLGLAVFSVL----CCFWPVGIAAFCLAHKTNKAWAKGDVQGAGAASRRAFLLGVLAVG 149
Query 113 LGI 115
LG+
Sbjct 150 LGL 152
>sp|Q3U4G0|CDIN1_MOUSE CDAN1-interacting nuclease 1 OS=Mus musculus
OX=10090 GN=Cdin1 PE=2 SV=2
Length=281
Score = 30.0 bits (66), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 13/41 (32%), Positives = 22/41 (54%), Gaps = 2/41 (5%)
Query 36 HNPAPPTSTVIH--IRSETSVPDHVVWSLFNTLFMNPCCLG 74
H PP+ +VI+ +R + +PD V+ + +N CC G
Sbjct 111 HEQTPPSKSVINSMLRDPSQIPDGVLANQVYQCIVNDCCYG 151
>sp|Q97CM5|DTDA_THEVO D-aminoacyl-tRNA deacylase OS=Thermoplasma
volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC
15438 / GSS1) OX=273116 GN=dtdA PE=3 SV=1
Length=256
Score = 30.0 bits (66), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 14/48 (29%), Positives = 22/48 (46%), Gaps = 0/48 (0%)
Query 47 HIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVT 94
HI S+ D W + + + P C GF+ +SR R MV ++
Sbjct 199 HIISKHDHDDLEEWQIKDAVEKTPSCKGFLVDRKGTRSRVRDMVKSIS 246
>sp|Q4JQW3|TEG1_VZVO Tegument protein UL46 homolog OS=Varicella-zoster
virus (strain Oka vaccine) OX=341980 GN=ORF12 PE=3
SV=1
Length=661
Score = 30.0 bits (66), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 0/53 (0%)
Query 6 QTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHV 58
T SPV+ P +Y +K E+E V + S + HI ++ S+ DHV
Sbjct 545 HTDGSPVDPTYPDHYTRIKAEYEGPVRDESNTMFDQRSDLRHIETQASLNDHV 597
>sp|P09264|TEG1_VZVD Tegument protein UL46 homolog OS=Varicella-zoster
virus (strain Dumas) OX=10338 GN=ORF12 PE=3 SV=1
Length=661
Score = 30.0 bits (66), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 0/53 (0%)
Query 6 QTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHV 58
T SPV+ P +Y +K E+E V + S + HI ++ S+ DHV
Sbjct 545 HTDGSPVDPTYPDHYTRIKAEYEGPVRDESNTMFDQRSDLRHIETQASLNDHV 597
>sp|O22920|CHX13_ARATH Cation/H(+) symporter 13 OS=Arabidopsis
thaliana OX=3702 GN=CHX13 PE=1 SV=1
Length=831
Score = 30.0 bits (66), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 26/111 (23%), Positives = 47/111 (42%), Gaps = 27/111 (24%)
Query 32 LGAPHNPAPPTSTVIHIRSETSVP-DHVVWSLFNTL------------FMNPCCLGFIAF 78
+G P + TS+ I + S TS P V + N L + C F+A
Sbjct 172 MGLPSDVISCTSSAISLSSMTSFPVTTTVLAELNILNSELGRLATHCSMVCEVCSWFVAL 231
Query 79 AYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVIPVLIF 129
A+++ +RDR M L ++I+G+L+ I + P++++
Sbjct 232 AFNLYTRDRTMTS--------------LYALSMIIGLLLVIYFVFRPIIVW 268
>sp|Q9Y2V0|CDIN1_HUMAN CDAN1-interacting nuclease 1 OS=Homo sapiens
OX=9606 GN=CDIN1 PE=1 SV=2
Length=281
Score = 29.6 bits (65), Expect = 8.9, Method: Compositional matrix adjust.
Identities = 12/41 (29%), Positives = 22/41 (54%), Gaps = 2/41 (5%)
Query 36 HNPAPPTSTVIH--IRSETSVPDHVVWSLFNTLFMNPCCLG 74
H PP+ ++I+ +R + +PD V+ + +N CC G
Sbjct 111 HEETPPSKSIINSMLRDPSQIPDGVLANQVYQCIVNDCCYG 151
>sp|Q8LPL3|ASO_ARATH L-ascorbate oxidase OS=Arabidopsis thaliana
OX=3702 GN=AAO PE=1 SV=1
Length=573
Score = 29.6 bits (65), Expect = 9.0, Method: Compositional matrix adjust.
Identities = 25/101 (25%), Positives = 43/101 (43%), Gaps = 9/101 (9%)
Query 30 AVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCC--LGFIAF----AYSVK 83
A G P P +I + ++ D+ WS+ N P LG I + AY +K
Sbjct 350 AAKGYPKPPEKSHDQLILLNTQNLYEDYTKWSINNVSLSVPVTPYLGSIRYGLKSAYDLK 409
Query 84 SRDRKMV---GDVTGAQAYASTAKCLNIWALILGILMTILL 121
S +K++ D+ +T K I+ GI++ ++L
Sbjct 410 SPAKKLIMDNYDIMKPPPNPNTTKGSGIYNFAFGIVVDVIL 450
>sp|O15018|PDZD2_HUMAN PDZ domain-containing protein 2 OS=Homo
sapiens OX=9606 GN=PDZD2 PE=1 SV=4
Length=2839
Score = 29.6 bits (65), Expect = 9.1, Method: Composition-based stats.
Identities = 15/52 (29%), Positives = 24/52 (46%), Gaps = 0/52 (0%)
Query 4 TVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP 55
+++TF SP+ S +P + + +AVL P P T R+E P
Sbjct 1978 SIRTFVSPLTSPKPVPEQGMWSRFHMAVLSEPDRGCPTTPKSPKCRAEGRAP 2029
Lambda K H a alpha
0.324 0.137 0.428 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 5113651884
Results from round 2
Query= sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein 3
OS=Homo sapiens OX=9606 GN=IFITM3 PE=1 SV=2
Length=133
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein 3 O... 213 2e-71
sp|Q01629|IFM2_HUMAN Interferon-induced transmembrane protein 2 O... 198 7e-66
sp|C9JQL5|DSA2D_HUMAN Putative dispanin subfamily A member 2d OS=... 178 1e-57
sp|Q9CQW9|IFM3_MOUSE Interferon-induced transmembrane protein 3 O... 176 8e-57
sp|P26376|IFM3_RAT Interferon-induced transmembrane protein 3 OS=... 173 8e-56
sp|Q99J93|IFM2_MOUSE Interferon-induced transmembrane protein 2 O... 165 2e-52
sp|P13164|IFM1_HUMAN Interferon-induced transmembrane protein 1 O... 159 2e-50
sp|Q5RAC1|PRRT2_PONAB Proline-rich transmembrane protein 2 OS=Pon... 149 1e-43
sp|Q7Z6L0|PRRT2_HUMAN Proline-rich transmembrane protein 2 OS=Hom... 145 2e-42
sp|D3ZFB6|PRRT2_RAT Proline-rich transmembrane protein 2 OS=Rattu... 144 4e-42
sp|E9PUL5|PRRT2_MOUSE Proline-rich transmembrane protein 2 OS=Mus... 144 5e-42
sp|Q9D103|IFM1_MOUSE Interferon-induced transmembrane protein 1 O... 135 5e-41
sp|A6NMD0|IFM10_HUMAN Interferon-induced transmembrane protein 10... 128 8e-37
sp|Q8BR26|IFM10_MOUSE Interferon-induced transmembrane protein 10... 121 3e-34
sp|A6NNB3|IFM5_HUMAN Interferon-induced transmembrane protein 5 O... 103 4e-28
sp|O88728|IFM5_MOUSE Interferon-induced transmembrane protein 5 O... 100 3e-27
sp|Q91499|DSA2B_TORMA Dispanin subfamily A member 2b OS=Torpedo m... 96.7 6e-26
Sequences not found previously or not previously below threshold:
sp|Q6DFT4|TARG1_XENTR Trafficking regulator of GLUT4 1 OS=Xenopus... 62.1 1e-11
sp|D3Z1U7|TM233_MOUSE Transmembrane protein 233 OS=Mus musculus O... 50.5 7e-08
sp|B4DJY2|TM233_HUMAN Transmembrane protein 233 OS=Homo sapiens O... 50.1 1e-07
sp|A0A1B0GWB2|PRT1B_HUMAN Proline rich transmembrane protein 1B O... 46.7 1e-05
sp|Q2MHH0|TARG1_RAT Trafficking regulator of GLUT4 1 OS=Rattus no... 44.0 7e-05
sp|Q8C838|TARG1_MOUSE Trafficking regulator of GLUT4 1 OS=Mus mus... 43.2 9e-05
sp|Q6MG82|PRRT1_RAT Proline-rich transmembrane protein 1 OS=Rattu... 41.3 8e-04
sp|O35449|PRRT1_MOUSE Proline-rich transmembrane protein 1 OS=Mus... 41.3 8e-04
sp|Q8IXB3|TARG1_HUMAN Trafficking regulator of GLUT4 1 OS=Homo sa... 40.9 8e-04
sp|Q99946|PRRT1_HUMAN Proline-rich transmembrane protein 1 OS=Hom... 40.9 0.001
sp|Q8C581|TMM91_MOUSE Transmembrane protein 91 OS=Mus musculus OX... 39.3 0.002
sp|Q6ZNR0|TMM91_HUMAN Transmembrane protein 91 OS=Homo sapiens OX... 39.3 0.003
sp|Q4R532|SYNG1_MACFA Synapse differentiation-inducing gene prote... 35.9 0.061
sp|Q6NFU3|TIG_CORDI Trigger factor OS=Corynebacterium diphtheriae... 35.9 0.066
sp|Q9H7V2|SYNG1_HUMAN Synapse differentiation-inducing gene prote... 35.5 0.067
sp|Q58DZ9|SYNG1_RAT Synapse differentiation-inducing gene protein... 35.1 0.097
sp|A2ANU3|SYNG1_MOUSE Synapse differentiation-inducing gene prote... 35.1 0.10
sp|Q08DM6|SYNG1_BOVIN Synapse differentiation-inducing gene prote... 34.7 0.13
sp|A4IFJ1|SYN1L_BOVIN Synapse differentiation-inducing gene prote... 32.4 0.99
sp|Q3USQ7|SYN1L_MOUSE Synapse differentiation-inducing gene prote... 32.0 1.1
sp|P11947|COX1_TETPY Cytochrome c oxidase subunit 1 OS=Tetrahymen... 32.0 1.4
sp|A6NDD5|SYN1L_HUMAN Synapse differentiation-inducing gene prote... 31.6 1.7
sp|P05489|COX1_PARTE Cytochrome c oxidase subunit 1 OS=Paramecium... 31.6 2.2
sp|A0A396JU32|ENOD2_MEDTR Early nodule-specific protein 2 OS=Medi... 30.9 3.6
sp|Q16643|DREB_HUMAN Drebrin OS=Homo sapiens OX=9606 GN=DBN1 PE=1... 30.9 4.0
sp|P49796|RGS3_HUMAN Regulator of G-protein signaling 3 OS=Homo s... 30.9 4.1
sp|Q66HA5|C2D1A_RAT Coiled-coil and C2 domain-containing protein ... 30.1 6.1
sp|P10637|TAU_MOUSE Microtubule-associated protein tau OS=Mus mus... 30.1 6.8
sp|P19332|TAU_RAT Microtubule-associated protein tau OS=Rattus no... 29.7 8.3
sp|Q5TZE2|SYN1L_DANRE Synapse differentiation-inducing gene prote... 29.3 9.7
>sp|Q01628|IFM3_HUMAN Interferon-induced transmembrane protein
3 OS=Homo sapiens OX=9606 GN=IFITM3 PE=1 SV=2
Length=133
Score = 213 bits (541), Expect = 2e-71, Method: Composition-based stats.
Identities = 133/133 (100%), Positives = 133/133 (100%), Gaps = 0/133 (0%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW
Sbjct 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120
SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL
Sbjct 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120
Query 121 LIVIPVLIFQAYG 133
LIVIPVLIFQAYG
Sbjct 121 LIVIPVLIFQAYG 133
>sp|Q01629|IFM2_HUMAN Interferon-induced transmembrane protein
2 OS=Homo sapiens OX=9606 GN=IFITM2 PE=1 SV=2
Length=132
Score = 198 bits (504), Expect = 7e-66, Method: Composition-based stats.
Identities = 120/131 (92%), Positives = 123/131 (94%), Gaps = 1/131 (1%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
MNH VQTF SPVNSGQPPNYEMLKEE EVA+LG PHNPAPP STVIHIRSETSVPDHVVW
Sbjct 1 MNHIVQTF-SPVNSGQPPNYEMLKEEQEVAMLGVPHNPAPPMSTVIHIRSETSVPDHVVW 59
Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120
SLFNTLFMN CCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI MTIL
Sbjct 60 SLFNTLFMNTCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGIFMTIL 119
Query 121 LIVIPVLIFQA 131
LI+IPVL+ QA
Sbjct 120 LIIIPVLVVQA 130
>sp|C9JQL5|DSA2D_HUMAN Putative dispanin subfamily A member 2d
OS=Homo sapiens OX=9606 PE=5 SV=1
Length=133
Score = 178 bits (451), Expect = 1e-57, Method: Composition-based stats.
Identities = 124/132 (94%), Positives = 129/132 (98%), Gaps = 0/132 (0%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
MNHTVQTFFSPVNSGQPPNYEMLKEEH+VAVLG PHNPAPPTSTVIHIRS+TSVP HVVW
Sbjct 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHKVAVLGVPHNPAPPTSTVIHIRSKTSVPHHVVW 60
Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIL 120
SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVG+VTGAQAYAST KCLNIWALILGILMTIL
Sbjct 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGNVTGAQAYASTTKCLNIWALILGILMTIL 120
Query 121 LIVIPVLIFQAY 132
LI+IPVLIFQA+
Sbjct 121 LIIIPVLIFQAH 132
>sp|Q9CQW9|IFM3_MOUSE Interferon-induced transmembrane protein
3 OS=Mus musculus OX=10090 GN=Ifitm3 PE=1 SV=1
Length=137
Score = 176 bits (445), Expect = 8e-57, Method: Composition-based stats.
Identities = 87/117 (74%), Positives = 97/117 (83%), Gaps = 0/117 (0%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
MNHT Q F + + GQPPNYE +KEE+EVA +GAPH A +TVI++ E SVPDHVVW
Sbjct 1 MNHTSQAFITAASGGQPPNYERIKEEYEVAEMGAPHGSASVRTTVINMPREVSVPDHVVW 60
Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILM 117
SLFNTLFMN CCLGFIA+AYSVKSRDRKMVGDVTGAQAYASTAKCLNI L+L ILM
Sbjct 61 SLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDVTGAQAYASTAKCLNISTLVLSILM 117
>sp|P26376|IFM3_RAT Interferon-induced transmembrane protein 3
OS=Rattus norvegicus OX=10116 GN=ifitm3 PE=2 SV=1
Length=137
Score = 173 bits (439), Expect = 8e-56, Method: Composition-based stats.
Identities = 86/117 (74%), Positives = 97/117 (83%), Gaps = 0/117 (0%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
MNHT Q F + GQPPNYE +KEE+EV+ LGAPH A +TVI++ E SVPDHVVW
Sbjct 1 MNHTSQAFVNAATGGQPPNYERIKEEYEVSELGAPHGSASVRTTVINMPREVSVPDHVVW 60
Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILM 117
SLFNTLFMN CCLGFIA+AYSVKSRDRKMVGD+TGAQAYASTAKCLNI +L+L ILM
Sbjct 61 SLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDMTGAQAYASTAKCLNISSLVLSILM 117
>sp|Q99J93|IFM2_MOUSE Interferon-induced transmembrane protein
2 OS=Mus musculus OX=10090 GN=Ifitm2 PE=1 SV=1
Length=144
Score = 165 bits (418), Expect = 2e-52, Method: Composition-based stats.
Identities = 84/137 (61%), Positives = 100/137 (73%), Gaps = 5/137 (4%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVW 60
M+H Q F S N+G PP+YE +KEE+ V LG P N A +TVI++ E SVPDHVVW
Sbjct 1 MSHNSQAFLS-TNAGLPPSYETIKEEYGVTELGEPSNSAVVRTTVINMPREVSVPDHVVW 59
Query 61 SLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMT-- 118
SLFNTLF N CCLGF+A+AYSVKSRDRKMVGDV GAQAYASTAKCLNI +LI ILM
Sbjct 60 SLFNTLFFNACCLGFVAYAYSVKSRDRKMVGDVVGAQAYASTAKCLNISSLIFSILMVII 119
Query 119 --ILLIVIPVLIFQAYG 133
I+ V++FQ++
Sbjct 120 CIIIFSTTSVVVFQSFA 136
>sp|P13164|IFM1_HUMAN Interferon-induced transmembrane protein
1 OS=Homo sapiens OX=9606 GN=IFITM1 PE=1 SV=3
Length=125
Score = 159 bits (403), Expect = 2e-50, Method: Composition-based stats.
Identities = 88/106 (83%), Positives = 93/106 (88%), Gaps = 0/106 (0%)
Query 22 MLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYS 81
M KEEHEVAVLG P + P STVI+I SETSVPDHVVWSLFNTLF+N CCLGFIAFAYS
Sbjct 1 MHKEEHEVAVLGPPPSTILPRSTVINIHSETSVPDHVVWSLFNTLFLNWCCLGFIAFAYS 60
Query 82 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVIPVL 127
VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTI I++ V
Sbjct 61 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTIGFILLLVF 106
>sp|Q5RAC1|PRRT2_PONAB Proline-rich transmembrane protein 2 OS=Pongo
abelii OX=9601 GN=PRRT2 PE=2 SV=1
Length=340
Score = 149 bits (375), Expect = 1e-43, Method: Composition-based stats.
Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 14/141 (10%)
Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55
H+ + SP +G PP + L EE + + H +P S H S+ + P
Sbjct 201 HSPPSKKSPPANGAPPRVLQQLVEEDRMGRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGE 260
Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109
D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I
Sbjct 261 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 319
Query 110 ALILGILMTILLIVIPVLIFQ 130
AL+ G+L+ I VI + +++
Sbjct 320 ALVGGVLIIIASCVINLGVYK 340
>sp|Q7Z6L0|PRRT2_HUMAN Proline-rich transmembrane protein 2 OS=Homo
sapiens OX=9606 GN=PRRT2 PE=1 SV=1
Length=340
Score = 145 bits (366), Expect = 2e-42, Method: Composition-based stats.
Identities = 41/141 (29%), Positives = 68/141 (48%), Gaps = 14/141 (10%)
Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55
H+ + SP +G PP + L EE + + H +P S H S+ + P
Sbjct 201 HSPPSKKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGE 260
Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109
D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I
Sbjct 261 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 319
Query 110 ALILGILMTILLIVIPVLIFQ 130
AL+ G+L+ I VI + +++
Sbjct 320 ALVGGVLIIIASCVINLGVYK 340
>sp|D3ZFB6|PRRT2_RAT Proline-rich transmembrane protein 2 OS=Rattus
norvegicus OX=10116 GN=Prrt2 PE=1 SV=1
Length=344
Score = 144 bits (364), Expect = 4e-42, Method: Composition-based stats.
Identities = 40/141 (28%), Positives = 67/141 (48%), Gaps = 14/141 (10%)
Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55
H+ + +P +G PP + L EE + H +P S H S+ + P
Sbjct 205 HSPPSTKTPPANGAPPRVLQKLVEEDRIGRAHGGHPGSPRGSLSRHPSSQLAGPGVEGGE 264
Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109
D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I
Sbjct 265 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 323
Query 110 ALILGILMTILLIVIPVLIFQ 130
AL+ G+L+ I VI + +++
Sbjct 324 ALVGGVLIIIASCVINLGVYK 344
>sp|E9PUL5|PRRT2_MOUSE Proline-rich transmembrane protein 2 OS=Mus
musculus OX=10090 GN=Prrt2 PE=1 SV=1
Length=346
Score = 144 bits (364), Expect = 5e-42, Method: Composition-based stats.
Identities = 40/141 (28%), Positives = 67/141 (48%), Gaps = 14/141 (10%)
Query 3 HTVQTFFSPVNSGQPPN-YEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVP------ 55
H+ + +P +G PP + L EE + H +P S H S+ + P
Sbjct 207 HSPPSTKTPPANGAPPRVLQKLVEEDRIGRAHGGHPGSPRGSLSRHPSSQLAGPGVEGGE 266
Query 56 ------DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109
D+++ ++ + F + +AFAY+V SR+ GDV GAQ AK L+I
Sbjct 267 GTQKPRDYIILAIL-SCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIV 325
Query 110 ALILGILMTILLIVIPVLIFQ 130
AL+ G+L+ I VI + +++
Sbjct 326 ALVGGVLIIIASCVINLGVYK 346
>sp|Q9D103|IFM1_MOUSE Interferon-induced transmembrane protein
1 OS=Mus musculus OX=10090 GN=Ifitm1 PE=2 SV=1
Length=106
Score = 135 bits (339), Expect = 5e-41, Method: Composition-based stats.
Identities = 70/103 (68%), Positives = 82/103 (80%), Gaps = 1/103 (1%)
Query 22 MLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYS 81
M KE+ EV VLG+PH T+T I++ E S PDHVVWSLFNTLFMN CCLGF+A+AYS
Sbjct 1 MPKEQQEVVVLGSPHISTSATATTINM-PEISTPDHVVWSLFNTLFMNFCCLGFVAYAYS 59
Query 82 VKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILLIVI 124
VKSRDRKMVGD TGAQA+ASTAKCLNI +L IL I++IV+
Sbjct 60 VKSRDRKMVGDTTGAQAFASTAKCLNISSLFFTILTAIVVIVV 102
>sp|A6NMD0|IFM10_HUMAN Interferon-induced transmembrane protein
10 OS=Homo sapiens OX=9606 GN=IFITM10 PE=1 SV=1
Length=228
Score = 128 bits (321), Expect = 8e-37, Method: Composition-based stats.
Identities = 43/125 (34%), Positives = 66/125 (53%), Gaps = 11/125 (9%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETS-VPDHVV 59
M S +G PP + L E+ + +TVI + +T+ V D+ +
Sbjct 106 MESKSSKTDSVRAAGAPPACKHLAEKKTMTN----------PTTVIEVYPDTTEVNDYYL 155
Query 60 WSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTI 119
WS+FN +++N CCLGFIA AYS+K RD+K++ D+ GA A TA+ NI + L I
Sbjct 156 WSIFNFVYLNFCCLGFIALAYSLKVRDKKLLNDLNGAVEDAKTARLFNITSSALAASCII 215
Query 120 LLIVI 124
L+ +
Sbjct 216 LVFIF 220
>sp|Q8BR26|IFM10_MOUSE Interferon-induced transmembrane protein
10 OS=Mus musculus OX=10090 GN=Ifitm10 PE=2 SV=3
Length=201
Score = 121 bits (302), Expect = 3e-34, Method: Composition-based stats.
Identities = 43/125 (34%), Positives = 65/125 (52%), Gaps = 11/125 (9%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETS-VPDHVV 59
M S SG P + L E+ + +TVI + +T+ V D+ +
Sbjct 79 MESKSSKTDSVRASGVPQACKHLAEKKTMTN----------PTTVIEVYPDTTEVNDYYL 128
Query 60 WSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTI 119
WS+FN +++N CCLGFIA AYS+K RD+K++ D+ GA A TA+ NI + L I
Sbjct 129 WSIFNFVYLNFCCLGFIALAYSLKVRDKKLLNDLNGAVEDAKTARLFNITSSALAASCII 188
Query 120 LLIVI 124
L+ +
Sbjct 189 LIFIF 193
>sp|A6NNB3|IFM5_HUMAN Interferon-induced transmembrane protein
5 OS=Homo sapiens OX=9606 GN=IFITM5 PE=1 SV=1
Length=132
Score = 103 bits (256), Expect = 4e-28, Method: Composition-based stats.
Identities = 39/86 (45%), Positives = 54/86 (63%), Gaps = 15/86 (17%)
Query 27 HEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRD 86
H LGAPH P DH++WS+F+TL++N CCLGF+A AYS+K+RD
Sbjct 21 HTALTLGAPHPPP---------------RDHLIWSVFSTLYLNLCCLGFLALAYSIKARD 65
Query 87 RKMVGDVTGAQAYASTAKCLNIWALI 112
+K+VGD+ A+ + S AKC NI A +
Sbjct 66 QKVVGDLEAARRFGSKAKCYNILAAM 91
>sp|O88728|IFM5_MOUSE Interferon-induced transmembrane protein
5 OS=Mus musculus OX=10090 GN=Ifitm5 PE=1 SV=1
Length=134
Score = 100 bits (250), Expect = 3e-27, Method: Composition-based stats.
Identities = 34/93 (37%), Positives = 55/93 (59%), Gaps = 9/93 (10%)
Query 29 VAVLGAPHNPAPPTSTVIHIRSETSV---------PDHVVWSLFNTLFMNPCCLGFIAFA 79
+ +P P+S + T++ DH++WS+F+T+++N CCLGF+A
Sbjct 1 MDTSYPREDPRAPSSRKADAAAHTALSMGTPGPTPRDHMLWSVFSTMYLNLCCLGFLALV 60
Query 80 YSVKSRDRKMVGDVTGAQAYASTAKCLNIWALI 112
+SVK+RD+KM G++ A+ Y S AKC NI A +
Sbjct 61 HSVKARDQKMAGNLEAARQYGSKAKCYNILAAM 93
>sp|Q91499|DSA2B_TORMA Dispanin subfamily A member 2b OS=Torpedo
marmorata OX=7788 PE=2 SV=1
Length=107
Score = 96.7 bits (239), Expect = 6e-26, Method: Composition-based stats.
Identities = 39/75 (52%), Positives = 48/75 (64%), Gaps = 1/75 (1%)
Query 38 PAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQ 97
P P S V + DH+ WS+FN +MN CCLG A +SVKSRDRK+VGDV GA+
Sbjct 9 PMSPRS-VQGAPGTLPIRDHLPWSIFNLFYMNVCCLGLTAMIFSVKSRDRKVVGDVEGAR 67
Query 98 AYASTAKCLNIWALI 112
Y STA+ LNI A +
Sbjct 68 HYGSTARSLNIAATV 82
>sp|Q6DFT4|TARG1_XENTR Trafficking regulator of GLUT4 1 OS=Xenopus
tropicalis OX=8364 GN=trarg1 PE=2 SV=1
Length=179
Score = 62.1 bits (149), Expect = 1e-11, Method: Composition-based stats.
Identities = 24/92 (26%), Positives = 50/92 (54%), Gaps = 2/92 (2%)
Query 39 APPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQA 98
A +ST + + D++V ++F + F + +A +S+ SR+ GD+ GA+
Sbjct 90 ARASSTATTAQEQGRPTDYLVLAIF-SCFCPVWPVNIVALVFSIMSRNSLQQGDLDGARR 148
Query 99 YASTAKCLNIWALILGILMTILLIVIPVLIFQ 130
A+ L++ +++LG L+ I+L ++ + IF
Sbjct 149 LGRLARLLSVVSILLG-LVIIVLCILSLTIFH 179
>sp|D3Z1U7|TM233_MOUSE Transmembrane protein 233 OS=Mus musculus
OX=10090 GN=Tmem233 PE=1 SV=2
Length=110
Score = 50.5 bits (119), Expect = 7e-08, Method: Composition-based stats.
Identities = 13/60 (22%), Positives = 25/60 (42%), Gaps = 0/60 (0%)
Query 51 ETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWA 110
+ P + +W + F + +A +S+ S + GD GA+ AK + I +
Sbjct 31 DIPAPSNYLWLTIISCFCPAYPVNIVALVFSIMSLNSYNDGDYEGARRLGRNAKWVAIAS 90
>sp|B4DJY2|TM233_HUMAN Transmembrane protein 233 OS=Homo sapiens
OX=9606 GN=TMEM233 PE=1 SV=1
Length=109
Score = 50.1 bits (118), Expect = 1e-07, Method: Composition-based stats.
Identities = 13/59 (22%), Positives = 25/59 (42%), Gaps = 0/59 (0%)
Query 51 ETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIW 109
+ +P + +W + F + +A +S+ S + GD GA+ AK + I
Sbjct 30 DVPMPKNYLWLTIVSCFCPAYPINIVALVFSIMSLNSYNDGDYEGARRLGRNAKWVAIA 88
>sp|A0A1B0GWB2|PRT1B_HUMAN Proline rich transmembrane protein
1B OS=Homo sapiens OX=9606 GN=PRRT1B PE=1 SV=1
Length=263
Score = 46.7 bits (109), Expect = 1e-05, Method: Composition-based stats.
Identities = 33/126 (26%), Positives = 54/126 (43%), Gaps = 18/126 (14%)
Query 4 TVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLF 63
T FSP P V P P +TV H D+++ S+
Sbjct 149 TPPALFSPPAGAAFP----------FPVYNGPMAGVPGPATVEHRPLP---KDYMMESVL 195
Query 64 NTLFMNPCCL--GFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTILL 121
TLF CCL G IA YS ++R GD+ A+ + A+ L +++L+ G+ ++
Sbjct 196 VTLF---CCLLTGLIAIVYSHEARAALGRGDLAQAEEASRKARSLVLFSLLFGVFVSTSW 252
Query 122 IVIPVL 127
++ V+
Sbjct 253 VIYVVV 258
>sp|Q2MHH0|TARG1_RAT Trafficking regulator of GLUT4 1 OS=Rattus
norvegicus OX=10116 GN=Trarg1 PE=1 SV=1
Length=173
Score = 44.0 bits (102), Expect = 7e-05, Method: Composition-based stats.
Identities = 11/51 (22%), Positives = 23/51 (45%), Gaps = 1/51 (2%)
Query 44 TVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVT 94
T + + + + D++V ++ + F L I +S+ SR GD+
Sbjct 88 TTSYAQDQEAPKDYLVLAI-ASCFCPVWPLNLIPLIFSIMSRSSVQQGDLD 137
>sp|Q8C838|TARG1_MOUSE Trafficking regulator of GLUT4 1 OS=Mus
musculus OX=10090 GN=Trarg1 PE=1 SV=1
Length=173
Score = 43.2 bits (100), Expect = 9e-05, Method: Composition-based stats.
Identities = 11/51 (22%), Positives = 23/51 (45%), Gaps = 1/51 (2%)
Query 44 TVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVT 94
T + + + + D++V ++ + F L I +S+ SR GD+
Sbjct 88 TTSYAQDQEAPKDYLVLAI-ASCFCPVWPLNLIPLIFSIMSRSSVQQGDLD 137
>sp|Q6MG82|PRRT1_RAT Proline-rich transmembrane protein 1 OS=Rattus
norvegicus OX=10116 GN=Prrt1 PE=1 SV=2
Length=306
Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats.
Identities = 18/76 (24%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query 56 DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI 115
D++ ++ T+ G IA +V+ R GD+ A+ + A+ + +L +GI
Sbjct 222 DYMPIAVLTTICC-FWPTGIIAIFKAVQVRTALARGDLVSAEIASREARNFSFISLAVGI 280
Query 116 LMTILLIVIPVLIFQA 131
+L ++ V+I A
Sbjct 281 AAMVLCTILTVVIIIA 296
>sp|O35449|PRRT1_MOUSE Proline-rich transmembrane protein 1 OS=Mus
musculus OX=10090 GN=Prrt1 PE=1 SV=1
Length=306
Score = 41.3 bits (95), Expect = 8e-04, Method: Composition-based stats.
Identities = 18/76 (24%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query 56 DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI 115
D++ ++ T+ G IA +V+ R GD+ A+ + A+ + +L +GI
Sbjct 222 DYMPIAVLTTICC-FWPTGIIAIFKAVQVRTALARGDLVSAEIASREARNFSFISLAVGI 280
Query 116 LMTILLIVIPVLIFQA 131
+L ++ V+I A
Sbjct 281 AAMVLCTILTVVIIIA 296
>sp|Q8IXB3|TARG1_HUMAN Trafficking regulator of GLUT4 1 OS=Homo
sapiens OX=9606 GN=TRARG1 PE=1 SV=2
Length=177
Score = 40.9 bits (94), Expect = 8e-04, Method: Composition-based stats.
Identities = 10/52 (19%), Positives = 22/52 (42%), Gaps = 1/52 (2%)
Query 43 STVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVT 94
+T + + + + D+++ ++ F L I S+ SR G+V
Sbjct 90 ATTSYAQDQEAPRDYLILAVV-ACFCPVWPLNLIPLIISIMSRSSMQQGNVD 140
>sp|Q99946|PRRT1_HUMAN Proline-rich transmembrane protein 1 OS=Homo
sapiens OX=9606 GN=PRRT1 PE=1 SV=2
Length=306
Score = 40.9 bits (94), Expect = 0.001, Method: Composition-based stats.
Identities = 18/76 (24%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query 56 DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI 115
D++ ++ T+ G IA +V+ R GD+ A+ + A+ + +L +GI
Sbjct 222 DYMPIAVLTTICC-FWPTGIIAIFKAVQVRTALARGDMVSAEIASREARNFSFISLAVGI 280
Query 116 LMTILLIVIPVLIFQA 131
+L ++ V+I A
Sbjct 281 AAMVLCTILTVVIIIA 296
>sp|Q8C581|TMM91_MOUSE Transmembrane protein 91 OS=Mus musculus
OX=10090 GN=Tmem91 PE=2 SV=1
Length=172
Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats.
Identities = 22/76 (29%), Positives = 36/76 (47%), Gaps = 2/76 (3%)
Query 56 DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI 115
DH+ ++F+ L +G AF + K+ GDV GA A + A L + A+ LG
Sbjct 94 DHLGLAVFSVLCC-FWPVGIAAFCLAHKTNKAWAKGDVQGAGAASRRAFLLGVLAVGLG- 151
Query 116 LMTILLIVIPVLIFQA 131
L T ++ + + A
Sbjct 152 LCTYAAALVTLAAYLA 167
>sp|Q6ZNR0|TMM91_HUMAN Transmembrane protein 91 OS=Homo sapiens
OX=9606 GN=TMEM91 PE=1 SV=1
Length=172
Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats.
Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 2/76 (3%)
Query 56 DHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI 115
DH+ ++F+ L +G AF + K+ GD+ GA A + A L + A+ LG+
Sbjct 94 DHLGLAVFSMLCC-FWPVGIAAFCLAQKTNKAWAKGDIQGAGAASRRAFLLGVLAVGLGV 152
Query 116 LMTILLIVIPVLIFQA 131
T ++ + + A
Sbjct 153 -CTYAAALVTLAAYLA 167
>sp|Q4R532|SYNG1_MACFA Synapse differentiation-inducing gene protein
1 OS=Macaca fascicularis OX=9541 GN=SYNDIG1 PE=2 SV=1
Length=258
Score = 35.9 bits (81), Expect = 0.061, Method: Composition-based stats.
Identities = 17/72 (24%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILG 114
DH+ S+F+ L LG AF S ++ GD+ A + A L + ++ +G
Sbjct 179 RDHLGLSVFSMLCC-FWPLGIAAFYLSHETNKAVAKGDLHQASTSSRRALFLAVLSITIG 237
Query 115 ILMTILLIVIPV 126
+ + + V +
Sbjct 238 TGVYVGVAVALI 249
>sp|Q6NFU3|TIG_CORDI Trigger factor OS=Corynebacterium diphtheriae
(strain ATCC 700971 / NCTC 13129 / Biotype gravis) OX=257309
GN=tig PE=3 SV=1
Length=448
Score = 35.9 bits (81), Expect = 0.066, Method: Composition-based stats.
Identities = 17/59 (29%), Positives = 29/59 (49%), Gaps = 8/59 (14%)
Query 12 VNSGQPPNYEMLKEEHEVAVLGAPH--------NPAPPTSTVIHIRSETSVPDHVVWSL 62
+N P Y+ + EE+E+ VLG PH N + + +R E +VPD +++
Sbjct 68 INDMLPTRYQQVVEENELVVLGQPHIDITKLEDNEVVEFTAEVDVRPEITVPDFSAFAV 126
>sp|Q9H7V2|SYNG1_HUMAN Synapse differentiation-inducing gene protein
1 OS=Homo sapiens OX=9606 GN=SYNDIG1 PE=1 SV=1
Length=258
Score = 35.5 bits (80), Expect = 0.067, Method: Composition-based stats.
Identities = 17/72 (24%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILG 114
DH+ S+F+ L LG AF S ++ GD+ A + A L + ++ +G
Sbjct 179 RDHLGLSVFSMLCC-FWPLGIAAFYLSHETNKAVAKGDLHQASTSSRRALFLAVLSITIG 237
Query 115 ILMTILLIVIPV 126
+ + + V +
Sbjct 238 TGVYVGVAVALI 249
>sp|Q58DZ9|SYNG1_RAT Synapse differentiation-inducing gene protein
1 OS=Rattus norvegicus OX=10116 GN=Syndig1 PE=1 SV=1
Length=258
Score = 35.1 bits (79), Expect = 0.097, Method: Composition-based stats.
Identities = 17/72 (24%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILG 114
DH+ S+F+ L LG AF S ++ GD A + A L + ++ +G
Sbjct 179 RDHLGLSVFSMLCC-FWPLGIAAFYLSHETNKAVAKGDFHQASTSSRRALFLAVLSITIG 237
Query 115 ILMTILLIVIPV 126
+ + + V +
Sbjct 238 TGIYVGVAVALI 249
>sp|A2ANU3|SYNG1_MOUSE Synapse differentiation-inducing gene protein
1 OS=Mus musculus OX=10090 GN=Syndig1 PE=1 SV=1
Length=258
Score = 35.1 bits (79), Expect = 0.10, Method: Composition-based stats.
Identities = 17/72 (24%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILG 114
DH+ S+F+ L LG AF S ++ GD A + A L + ++ +G
Sbjct 179 RDHLGLSVFSMLCC-FWPLGIAAFYLSHETNKAVAKGDFHQASTSSRRALFLAVLSITIG 237
Query 115 ILMTILLIVIPV 126
+ + + V +
Sbjct 238 TGIYVGVAVALI 249
>sp|Q08DM6|SYNG1_BOVIN Synapse differentiation-inducing gene protein
1 OS=Bos taurus OX=9913 GN=SYNDIG1 PE=2 SV=1
Length=258
Score = 34.7 bits (78), Expect = 0.13, Method: Composition-based stats.
Identities = 17/72 (24%), Positives = 31/72 (43%), Gaps = 1/72 (1%)
Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILG 114
DH+ S+F+ L LG AF S ++ GD A + A L + ++ +G
Sbjct 179 RDHLGLSVFSMLCC-FWPLGIAAFYLSHETNKAVAKGDFHQASTSSRRALFLAVLSITIG 237
Query 115 ILMTILLIVIPV 126
+ + + V +
Sbjct 238 TGIYVGVAVALI 249
>sp|A4IFJ1|SYN1L_BOVIN Synapse differentiation-inducing gene protein
1-like OS=Bos taurus OX=9913 GN=SYNDIG1L PE=2 SV=1
Length=238
Score = 32.4 bits (72), Expect = 0.99, Method: Composition-based stats.
Identities = 19/96 (20%), Positives = 35/96 (36%), Gaps = 5/96 (5%)
Query 24 KEEHEVAVLGAPHNPAPPTSTVIHIRSE--TSVP--DHVVWSLFNTLFMNPCCLGFIAFA 79
+E G P ++ + ++P DH+ ++F+ L LG AF
Sbjct 124 VQEEFQGQEGDPEEEESDATSTESESEDNFLTLPPRDHLGLTIFSMLCC-FWPLGIAAFY 182
Query 80 YSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGI 115
+S + GD A + A L ++ +G
Sbjct 183 FSQGTSKAISKGDFRLANTTSRRALFLATLSIAVGA 218
>sp|Q3USQ7|SYN1L_MOUSE Synapse differentiation-inducing gene protein
1-like OS=Mus musculus OX=10090 GN=Syndig1l PE=2 SV=1
Length=237
Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats.
Identities = 17/80 (21%), Positives = 27/80 (34%), Gaps = 1/80 (1%)
Query 36 HNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTG 95
+ S DH+ +LF+ L LG AF +S + GD
Sbjct 139 SDGTSSESECEDAFLTLPPRDHLGLTLFSMLCC-FWPLGIAAFYFSQGTSKAISKGDFRL 197
Query 96 AQAYASTAKCLNIWALILGI 115
A + A L ++ +G
Sbjct 198 ASTTSRRALFLATLSIAVGA 217
>sp|P11947|COX1_TETPY Cytochrome c oxidase subunit 1 OS=Tetrahymena
pyriformis OX=5908 GN=COI PE=3 SV=1
Length=698
Score = 32.0 bits (71), Expect = 1.4, Method: Composition-based stats.
Identities = 27/128 (21%), Positives = 46/128 (36%), Gaps = 4/128 (3%)
Query 3 HTVQTFFSPVNSGQPPNYEMLK---EEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVV 59
H TFF G P + L EV VL P + + H++
Sbjct 375 HWQTTFFEYAYGGDPILSQHLFWFFGHPEVYVLIIPTFGFINMIVPHNNTRRVASKHHMI 434
Query 60 WSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLN-IWALILGILMT 118
W+++ +M G + + R R M +T + +T K +N +L+ G L
Sbjct 435 WAIYVMAYMGYLVWGHHMYLVGLDHRSRTMYSTITIMISMPATIKVVNWTLSLVNGALKV 494
Query 119 ILLIVIPV 126
L + +
Sbjct 495 DLPFLFSM 502
>sp|A6NDD5|SYN1L_HUMAN Synapse differentiation-inducing gene protein
1-like OS=Homo sapiens OX=9606 GN=SYNDIG1L PE=3 SV=1
Length=238
Score = 31.6 bits (70), Expect = 1.7, Method: Composition-based stats.
Identities = 17/61 (28%), Positives = 25/61 (41%), Gaps = 1/61 (2%)
Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILG 114
DH+ +LF+ L LG AF +S + GD A + A L A+ +G
Sbjct 159 RDHLGLTLFSMLCC-FWPLGIAAFYFSQGTSKAISKGDFRLASTTSRRALFLATLAIAVG 217
Query 115 I 115
Sbjct 218 A 218
>sp|P05489|COX1_PARTE Cytochrome c oxidase subunit 1 OS=Paramecium
tetraurelia OX=5888 GN=COI PE=3 SV=1
Length=645
Score = 31.6 bits (70), Expect = 2.2, Method: Composition-based stats.
Identities = 25/128 (20%), Positives = 44/128 (34%), Gaps = 4/128 (3%)
Query 3 HTVQTFFSPVNSGQPPNYEMLK---EEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVV 59
H +FF G P ++ L EV +L P + S H++
Sbjct 317 HWQTSFFDFAYGGDPILFQHLFWFFGHPEVYILIIPSFGVANIVLPFYTMRRMSSKHHMI 376
Query 60 WSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGILMTI 119
W+++ +M G + + R R + +T +T K +N W L L
Sbjct 377 WAVYVMAYMGFVVWGHHMYLVGLDHRSRNIYSTITIMICLPATIKLVN-WTLTLANAAIH 435
Query 120 LLIVIPVL 127
+ +V
Sbjct 436 VDLVFLFF 443
>sp|A0A396JU32|ENOD2_MEDTR Early nodule-specific protein 2 OS=Medicago
truncatula OX=3880 GN=ENOD2 PE=2 SV=1
Length=593
Score = 30.9 bits (68), Expect = 3.6, Method: Composition-based stats.
Identities = 11/40 (28%), Positives = 16/40 (40%), Gaps = 0/40 (0%)
Query 2 NHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPP 41
+ F+P + PPNY + E + PH PP
Sbjct 485 HENPPPEFAPPHKKLPPNYNPPRHEKPMPKYQPPHEKLPP 524
>sp|Q16643|DREB_HUMAN Drebrin OS=Homo sapiens OX=9606 GN=DBN1
PE=1 SV=4
Length=649
Score = 30.9 bits (68), Expect = 4.0, Method: Composition-based stats.
Identities = 19/52 (37%), Positives = 22/52 (42%), Gaps = 0/52 (0%)
Query 1 MNHTVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSET 52
M Q P G P M E E AVL AP PA +T IH ++T
Sbjct 401 MEEPPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDAADT 452
>sp|P49796|RGS3_HUMAN Regulator of G-protein signaling 3 OS=Homo
sapiens OX=9606 GN=RGS3 PE=1 SV=2
Length=1198
Score = 30.9 bits (68), Expect = 4.1, Method: Composition-based stats.
Identities = 11/47 (23%), Positives = 15/47 (32%), Gaps = 0/47 (0%)
Query 5 VQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSE 51
SP P+ E L + G+P P P S + E
Sbjct 723 PPNKDSPSGQEPAPSQEPLSSKDSATSEGSPPGPDAPPSKDVPPCQE 769
>sp|Q66HA5|C2D1A_RAT Coiled-coil and C2 domain-containing protein
1A OS=Rattus norvegicus OX=10116 GN=Cc2d1a PE=1 SV=2
Length=941
Score = 30.1 bits (66), Expect = 6.1, Method: Composition-based stats.
Identities = 21/97 (22%), Positives = 30/97 (31%), Gaps = 2/97 (2%)
Query 11 PVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHVVWSLFNTLFMNP 70
PV SG+ P H + L PAP S + S T+ +
Sbjct 192 PVASGKGPAIGH-SHTHTTSHLAPVSPPAPEPSVTLEAPSTTAQTSAKPQLSPDPC-SPL 249
Query 71 CCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLN 107
L + Y V + K D A Y +K +
Sbjct 250 ARLQSLQHEYKVAALRAKHQDDTATAARYLRVSKSFD 286
>sp|P10637|TAU_MOUSE Microtubule-associated protein tau OS=Mus
musculus OX=10090 GN=Mapt PE=1 SV=3
Length=733
Score = 30.1 bits (66), Expect = 6.8, Method: Composition-based stats.
Identities = 14/55 (25%), Positives = 20/55 (36%), Gaps = 3/55 (5%)
Query 4 TVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHV 58
T + +P SG+PP E + G+P P + T T P V
Sbjct 467 TTPSPKTPPGSGEPPKS---GERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKV 518
>sp|P19332|TAU_RAT Microtubule-associated protein tau OS=Rattus
norvegicus OX=10116 GN=Mapt PE=1 SV=3
Length=752
Score = 29.7 bits (65), Expect = 8.3, Method: Composition-based stats.
Identities = 14/55 (25%), Positives = 20/55 (36%), Gaps = 3/55 (5%)
Query 4 TVQTFFSPVNSGQPPNYEMLKEEHEVAVLGAPHNPAPPTSTVIHIRSETSVPDHV 58
T + +P SG+PP E + G+P P + T T P V
Sbjct 486 TTPSPKTPPGSGEPPKS---GERSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKV 537
>sp|Q5TZE2|SYN1L_DANRE Synapse differentiation-inducing gene protein
1-like OS=Danio rerio OX=7955 GN=syndig1l PE=3 SV=1
Length=258
Score = 29.3 bits (64), Expect = 9.7, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 23/57 (40%), Gaps = 1/57 (2%)
Query 55 PDHVVWSLFNTLFMNPCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWAL 111
DH+ ++F+ L LG AF +S + GD A + A L ++
Sbjct 179 RDHLGLAIFSMLCC-FWPLGIAAFYFSQGTSKAVTKGDFPLASIASRRALFLAALSI 234
Lambda K H a alpha
0.317 0.125 0.330 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0384 0.140 1.90 42.6 43.6
Effective search space used: 5113651884
Database: uniprot_sprot.fasta
Posted date: Aug 1, 2024 3:29 PM
Number of letters in database: 207,016,062
Number of sequences in database: 571,864
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40