PSIBLAST 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Stephen F.
Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala,
Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005)
"Protein database searches using compositionally adjusted
substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: uniprot_sprot.fasta
573,661 sequences; 207,922,125 total letters
Results from round 1
Query= sp|P49754|VPS41_HUMAN Vacuolar protein sorting-associated protein 41
homolog OS=Homo sapiens OX=9606 GN=VPS41 PE=1 SV=3
Length=854
Score E
Sequences producing significant alignments: (Bits) Value
sp|P49754|VPS41_HUMAN Vacuolar protein sorting-associated protein... 1765 0.0
sp|Q5KU39|VPS41_MOUSE Vacuolar protein sorting-associated protein... 1727 0.0
sp|E7F590|VPS41_DANRE Vacuolar protein sorting-associated protein... 1439 0.0
sp|Q7PL76|VPS41_DROME Vacuolar protein sorting-associated protein... 548 0.0
sp|P93231|VPS41_SOLLC Vacuolar protein sorting-associated protein... 548 1e-180
sp|P93043|VPS41_ARATH Vacuolar protein sorting-associated protein... 548 3e-180
sp|Q9P7N3|VPS41_SCHPO Vacuolar protein sorting-associated protein... 375 1e-115
sp|Q19954|VPS41_CAEEL Vacuolar protein sorting-associated protein... 343 2e-103
sp|Q618H8|VPS41_CAEBR Vacuolar protein sorting-associated protein... 320 8e-95
sp|P38959|VPS41_YEAST Vacuolar protein sorting-associated protein... 229 7e-62
sp|Q24314|VPS18_DROME Vacuolar protein sorting-associated protein... 46.2 0.002
sp|P59015|VPS18_DANRE Vacuolar protein sorting-associated protein... 41.6 0.037
sp|Q9H270|VPS11_HUMAN Vacuolar protein sorting-associated protein... 41.2 0.046
sp|P57232|QUEA_BUCAI S-adenosylmethionine:tRNA ribosyltransferase... 40.8 0.050
sp|B8D737|QUEA_BUCAT S-adenosylmethionine:tRNA ribosyltransferase... 40.4 0.051
sp|B8D8T3|QUEA_BUCA5 S-adenosylmethionine:tRNA ribosyltransferase... 40.4 0.052
sp|Q8R307|VPS18_MOUSE Vacuolar protein sorting-associated protein... 41.2 0.054
sp|Q9P253|VPS18_HUMAN Vacuolar protein sorting-associated protein... 40.0 0.11
sp|Q91W86|VPS11_MOUSE Vacuolar protein sorting-associated protein... 39.3 0.20
sp|Q23194|VPS18_CAEEL Vacuolar protein sorting-associated protein... 38.5 0.34
sp|P39702|VPS8_YEAST Vacuolar protein sorting-associated protein ... 38.1 0.44
sp|Q54YP4|VPS11_DICDI Vacuolar protein sorting-associated protein... 37.7 0.56
sp|F4I312|VPS3_ARATH Vacuolar sorting protein 3 OS=Arabidopsis th... 37.4 0.77
sp|Q4PH43|MTAP_MYCMD S-methyl-5'-thioadenosine phosphorylase OS=M... 36.6 0.78
sp|Q9ERF3|SKI8_MOUSE Superkiller complex protein 8 OS=Mus musculu... 36.6 0.87
sp|Q32LN7|SKI8_BOVIN Superkiller complex protein 8 OS=Bos taurus ... 36.2 1.1
sp|Q6P5M2|SKI8_DANRE Superkiller complex protein 8 OS=Danio rerio... 36.2 1.1
sp|Q9GZS3|SKI8_HUMAN Superkiller complex protein 8 OS=Homo sapien... 36.2 1.1
sp|Q5ZJH5|SKI8_CHICK Superkiller complex protein 8 OS=Gallus gall... 35.8 1.6
sp|O18388|IMB_DROME Importin subunit beta OS=Drosophila melanogas... 36.2 1.7
sp|A4REK3|SEC13_PYRO7 Protein transport protein SEC13 OS=Pyricula... 35.4 1.8
sp|Q6ZJX0|FIE2_ORYSJ Polycomb group protein FIE1 OS=Oryza sativa ... 35.8 1.9
sp|Q8AWW4|RN128_XENLA E3 ubiquitin-protein ligase RNF128 OS=Xenop... 35.4 2.2
sp|Q90WG6|NEUA_ONCMY N-acylneuraminate cytidylyltransferase OS=On... 35.0 2.9
sp|Q4V7A0|SKI8_RAT Superkiller complex protein 8 OS=Rattus norveg... 34.7 3.1
sp|Q96KV7|WDR90_HUMAN WD repeat-containing protein 90 OS=Homo sap... 35.4 3.2
sp|Q10322|DMA1_SCHPO Probable E3 ubiquitin-protein ligase dma1 OS... 34.7 3.3
sp|Q9VEA2|VPS39_DROME Vacuolar protein sorting-associated protein... 35.0 3.6
sp|Q9SUS5|RHA1B_ARATH E3 ubiquitin-protein ligase RHA1B OS=Arabid... 33.1 4.8
sp|Q6ZPG2|WDR90_MOUSE WD repeat-containing protein 90 OS=Mus musc... 34.7 4.9
sp|Q9SJ40|VPS11_ARATH Vacuolar protein-sorting-associated protein... 34.7 5.1
sp|Q29HG9|LST8_DROPS Protein LST8 homolog OS=Drosophila pseudoobs... 33.9 6.0
sp|P73594|Y1409_SYNY3 WD repeat-containing protein slr1409 OS=Syn... 33.9 7.1
sp|A1S3I3|HLDE_SHEAM Bifunctional protein HldE OS=Shewanella amaz... 33.9 8.3
sp|Q9W328|LST8_DROME Protein LST8 homolog OS=Drosophila melanogas... 33.5 9.2
>sp|P49754|VPS41_HUMAN Vacuolar protein sorting-associated protein
41 homolog OS=Homo sapiens OX=9606 GN=VPS41 PE=1 SV=3
Length=854
Score = 1765 bits (4571), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 854/854 (100%), Positives = 854/854 (100%), Gaps = 0/854 (0%)
Query 1 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL 60
MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL
Sbjct 1 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL 60
Query 61 GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH 120
GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH
Sbjct 61 GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH 120
Query 121 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR 180
ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR
Sbjct 121 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR 180
Query 181 GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV 240
GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV
Sbjct 181 GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV 240
Query 241 CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA 300
CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA
Sbjct 241 CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA 300
Query 301 RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER 360
RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER
Sbjct 301 RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER 360
Query 361 DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK 420
DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK
Sbjct 361 DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK 420
Query 421 ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI 480
ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI
Sbjct 421 ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI 480
Query 481 REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF 540
REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF
Sbjct 481 REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF 540
Query 541 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK 600
QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK
Sbjct 541 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK 600
Query 601 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL 660
LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL
Sbjct 601 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL 660
Query 661 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH 720
SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH
Sbjct 661 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH 720
Query 721 VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM 780
VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM
Sbjct 721 VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM 780
Query 781 KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA 840
KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA
Sbjct 781 KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA 840
Query 841 KNRGPGSAILEMKK 854
KNRGPGSAILEMKK
Sbjct 841 KNRGPGSAILEMKK 854
>sp|Q5KU39|VPS41_MOUSE Vacuolar protein sorting-associated protein
41 homolog OS=Mus musculus OX=10090 GN=Vps41 PE=1 SV=1
Length=853
Score = 1727 bits (4474), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 830/854 (97%), Positives = 848/854 (99%), Gaps = 1/854 (0%)
Query 1 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL 60
MAEAEEQET SLEESTDESEEE SEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL
Sbjct 1 MAEAEEQETESLEESTDESEEE-SEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL 59
Query 61 GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH 120
GTHYGKVYLLDVQGNITQKFDVSPVKINQISLD+SGEHMGVCSEDGK+QVFGLYSGEEFH
Sbjct 60 GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDDSGEHMGVCSEDGKLQVFGLYSGEEFH 119
Query 121 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR 180
ETFDCPIKIIAVHP FVRSSCKQFVTGGKKLLLFER+WMNRWKS+VLHEGEGNIRSVKWR
Sbjct 120 ETFDCPIKIIAVHPQFVRSSCKQFVTGGKKLLLFERTWMNRWKSSVLHEGEGNIRSVKWR 179
Query 181 GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV 240
GHLIAWANNMGVK+FDI SKQRI+NVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTS+K+
Sbjct 180 GHLIAWANNMGVKVFDITSKQRISNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSIKI 239
Query 241 CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA 300
CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKE+SEKTEREYCA
Sbjct 240 CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEVSEKTEREYCA 299
Query 301 RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER 360
RPRLDIIQPL ETCEEISSDALTVRGFQENECRDYHLEYSEGESLFY+VSPRDVVVAKER
Sbjct 300 RPRLDIIQPLPETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYVVSPRDVVVAKER 359
Query 361 DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK 420
DQDDHIDWLLEKKKYEEALMAAEISQ+NIKRHKILDIGLAY+NHLVERG+YD+AARKCQK
Sbjct 360 DQDDHIDWLLEKKKYEEALMAAEISQRNIKRHKILDIGLAYVNHLVERGEYDMAARKCQK 419
Query 421 ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI 480
ILGKNA+LWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI
Sbjct 420 ILGKNASLWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI 479
Query 481 REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF 540
REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF
Sbjct 480 REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF 539
Query 541 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK 600
QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK
Sbjct 540 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK 599
Query 601 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL 660
LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL
Sbjct 600 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL 659
Query 661 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH 720
SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH
Sbjct 660 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH 719
Query 721 VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM 780
VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM
Sbjct 720 VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM 779
Query 781 KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA 840
KGVLVDEENICESCLSPILP+DAAKPFSVVVFHCRHMFHKECLPMPSMN+ AQ+CNICSA
Sbjct 780 KGVLVDEENICESCLSPILPTDAAKPFSVVVFHCRHMFHKECLPMPSMNAPAQYCNICSA 839
Query 841 KNRGPGSAILEMKK 854
KNRGPGSAILEMKK
Sbjct 840 KNRGPGSAILEMKK 853
>sp|E7F590|VPS41_DANRE Vacuolar protein sorting-associated protein
41 homolog OS=Danio rerio OX=7955 GN=vps41 PE=1 SV=1
Length=854
Score = 1439 bits (3726), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 702/854 (82%), Positives = 768/854 (90%), Gaps = 0/854 (0%)
Query 1 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL 60
MAE EEQ EESTDESEEE++EEEPKLKYERL+NGVTEILQKDAASCMTVHDKFLAL
Sbjct 1 MAEVEEQGRKLSEESTDESEEEDTEEEPKLKYERLTNGVTEILQKDAASCMTVHDKFLAL 60
Query 61 GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH 120
GTH+GKV+LLD+QGN+TQKF++S VKINQISLDESG+H+G+CSEDGKVQVFGLY+ E FH
Sbjct 61 GTHFGKVFLLDIQGNVTQKFEISSVKINQISLDESGDHVGICSEDGKVQVFGLYTREGFH 120
Query 121 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR 180
E FDCPIK++A+HP F +S+ KQFVTGG KLLL+ER+W+NRWK++VLHEGEGNI SVKWR
Sbjct 121 ENFDCPIKVVALHPQFSKSNNKQFVTGGNKLLLYERNWLNRWKTSVLHEGEGNITSVKWR 180
Query 181 GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV 240
G+LIAWANN+GVKI+DI SKQRITNV RD+ SLRPDMYPCSLCWKDN TLIIGWG SVK+
Sbjct 181 GNLIAWANNVGVKIYDIGSKQRITNVLRDNTSLRPDMYPCSLCWKDNTTLIIGWGCSVKI 240
Query 241 CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA 300
C+VKER +EMRDLPSRYVEIVS FETEF+ISGLAPL DQLV L YVKE S+ E E+
Sbjct 241 CAVKERDPTEMRDLPSRYVEIVSAFETEFFISGLAPLADQLVTLYYVKENSDHMEEEFRT 300
Query 301 RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER 360
RPRLDIIQPL E CEEISSDALTVR FQEN+CRDY LE+SEGESLFYI+SP+D+VVAKER
Sbjct 301 RPRLDIIQPLPEGCEEISSDALTVRNFQENQCRDYRLEHSEGESLFYIISPKDIVVAKER 360
Query 361 DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK 420
DQDDHIDWLLEKKKYEEALMAAEIS KNIKRH + IG+AYINHLVE+GDYD AARKCQK
Sbjct 361 DQDDHIDWLLEKKKYEEALMAAEISFKNIKRHDVQKIGMAYINHLVEKGDYDTAARKCQK 420
Query 421 ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI 480
+LGKN LWE EVY+FK IGQLKAIS YLPRGD L+P IYEMILH+FL++DYEGFATLI
Sbjct 421 VLGKNMDLWENEVYRFKTIGQLKAISQYLPRGDLRLRPAIYEMILHDFLKTDYEGFATLI 480
Query 481 REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF 540
REWPG+LYNN IVQAV +HLKKD N LL TLAELYTYD+ Y ALEIYL LRHKDV+
Sbjct 481 REWPGELYNNMAIVQAVNEHLKKDPTNSILLTTLAELYTYDQRYDRALEIYLRLRHKDVY 540
Query 541 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK 600
QLIHKHNLFSSIKDKIVLLMDFD EKAVDMLLDNEDKIS+ KVVEEL+DRPEL HVYLHK
Sbjct 541 QLIHKHNLFSSIKDKIVLLMDFDKEKAVDMLLDNEDKISMDKVVEELKDRPELLHVYLHK 600
Query 601 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL 660
LFKRDHHKGQ+YHE+QISLYAE+DRPNLLPFLR+S HCPLEKALEICQQR+FVEETV+LL
Sbjct 601 LFKRDHHKGQKYHERQISLYAEFDRPNLLPFLRESMHCPLEKALEICQQRHFVEETVFLL 660
Query 661 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH 720
SRMGN R AL+MIMEEL +VDKAIEFAKEQDD ELWEDLI YSIDKPPFITGLLNNIGTH
Sbjct 661 SRMGNCRRALQMIMEELANVDKAIEFAKEQDDRELWEDLISYSIDKPPFITGLLNNIGTH 720
Query 721 VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM 780
VDPILLIHRIKEGMEIPNLRDSLVKIL DYNLQILLREGCKKILVADSLSLL++MHRTQ
Sbjct 721 VDPILLIHRIKEGMEIPNLRDSLVKILHDYNLQILLREGCKKILVADSLSLLQRMHRTQK 780
Query 781 KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA 840
KGV VDEENICESC +PILPSD A+ F VVVFHCRHMFHKECLP P Q+CNICSA
Sbjct 781 KGVRVDEENICESCHTPILPSDTAQAFGVVVFHCRHMFHKECLPSPGSIPGIQYCNICSA 840
Query 841 KNRGPGSAILEMKK 854
K RGPGS ILEMKK
Sbjct 841 KRRGPGSGILEMKK 854
>sp|Q7PL76|VPS41_DROME Vacuolar protein sorting-associated protein
41 homolog OS=Drosophila melanogaster OX=7227 GN=lt PE=1
SV=2
Length=841
Score = 548 bits (1411), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 317/834 (38%), Positives = 488/834 (59%), Gaps = 36/834 (4%)
Query 23 ESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGN-ITQKFD 81
E + EPK KY RL+N + +L D +C VH KFL GT G+V + D QGN +
Sbjct 19 EEDVEPKFKYHRLANDLKYMLNADVITCSAVHLKFLIFGTFRGRVCIFDHQGNSVYSNLS 78
Query 82 VS-----PVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE-TFDCPIKIIAVHPH 135
S V +N I +D GE++ CS+DGKV + GL+S + H +F IK++++ P
Sbjct 79 ASERHTHQVAVNNIDVDHKGEYVATCSDDGKVNITGLFSSDNNHSLSFGKFIKVVSLEPD 138
Query 136 FVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIF 195
++ K+FV G KL+L+ER+ + + K L EG++ S+ W G+ IAWA+++GV+++
Sbjct 139 -SKAHIKRFVVGDDKLILYERNLLKKLKPVELCSVEGSVLSICWHGNFIAWASHIGVRVY 197
Query 196 DIISKQRIT----NVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEM 251
D+ + + VP + R + + C L W + TL+IGW +++VC +++R++ E
Sbjct 198 DLNERCSLGLIKWEVPPQE---RLENFRCHLRWSNKHTLLIGWVDTIRVCVIRKRNSIEA 254
Query 252 R--DLPSRYVEIVSQFETEFYISGLAPL-CDQLVVLSYVKEISEKTEREYCARPRLDIIQ 308
+LP V+ +S F+T FY+ GLAPL QLVVL + KE K+ RP L +I+
Sbjct 255 STGNLPVYIVDPISTFQTTFYVCGLAPLSAKQLVVLGFRKE---KSSCFKALRPVLCVIE 311
Query 309 PLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQDDHIDW 368
EEI +D+LT+RGF+E DY L E+ FYIV+P+D+VVA + DD I+W
Sbjct 312 YKMNNSEEICTDSLTLRGFEEYTVNDYSLGGIIEENRFYIVAPKDIVVASLIETDDRIEW 371
Query 369 LLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAAL 428
L++ K+EEA+ E+ N +L + YINHL+ YD AA+ C ++LG + L
Sbjct 372 LIKHSKFEEAM---ELISANGGNVPVLSVAKLYINHLLALKKYDDAAKLCLRMLGNDKVL 428
Query 429 WEYEVYKFKEIGQLKAISPYLPRGDPV-LKPLIYEMILHEFLESDYEGFATLIREWPGDL 487
WE EV+KF + QL+++S YLP D L P +YEM+L+EFL+ D GF LI+EWP L
Sbjct 429 WEEEVFKFVKCQQLRSVSAYLPTSDECKLDPHVYEMVLYEFLKFDVCGFLNLIKEWPSHL 488
Query 488 YNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHN 547
Y+ ++ A+ D+ +K N+ LL++LA LY+Y ++ +AL +YL L++KDVFQLI ++
Sbjct 489 YDGLAVINAIHDNFRKHYANQ-LLESLALLYSYQGDFESALRMYLKLQNKDVFQLIRRYE 547
Query 548 LFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHH 607
L+ I I+ L+ D + A ++LLD + KI + VV +LE E + YL L K+D
Sbjct 548 LYDVISKLIIPLIQLDRDCAFEILLDKK-KIKTEIVVHQLEHNQEYLYWYLDSLLKKD-- 604
Query 608 KGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGN-- 665
+ +K ISLYA +DR LLPFL+ S +++AL IC+Q NF E VYLL MG
Sbjct 605 PSNVFQKKLISLYAIFDRNKLLPFLKRSKDYDIQEALVICKQENFYPEIVYLLGCMGGVE 664
Query 666 SRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPIL 725
+ AL +I+ + D++ AIEF KE DD +LW LI P +T +L+ I + P +
Sbjct 665 ASEALNIIIHRIRDIEMAIEFCKEHDDSDLWNALINEFSKHPEIVTKVLDGIVDYFSPAV 724
Query 726 LIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLV 785
++ +IK G IPNLR SL+K+L+ YNLQ + ++I + D + ++ TQ +G V
Sbjct 725 VVGKIKMGQNIPNLRQSLIKMLRHYNLQGEILSSAQQIQLNDYFEIHSEIVTTQRRGQQV 784
Query 786 DEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICS 839
E +C C P+L + + ++ C H++HK C+ + + CN C+
Sbjct 785 SYEQLCSLCHRPVLMA-GTHLYCIIRLECGHVYHKPCIQGELLKN----CNECN 833
>sp|P93231|VPS41_SOLLC Vacuolar protein sorting-associated protein
41 homolog OS=Solanum lycopersicum OX=4081 GN=VPS41 PE=2
SV=1
Length=960
Score = 548 bits (1412), Expect = 1e-180, Method: Compositional matrix adjust.
Identities = 311/871 (36%), Positives = 489/871 (56%), Gaps = 85/871 (10%)
Query 28 PKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKI 87
P+LKY+R+ V +L DAA+C+ V ++ +ALGTH G V++LD GN ++F +
Sbjct 36 PRLKYQRMGASVPSLLSADAATCIAVAERMIALGTHGGAVHILDFLGNQVKEFAAHTAAV 95
Query 88 NQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTG 147
N + D GE++G CS+DG V + L++ E + P+K IA+ P + R+S ++FVTG
Sbjct 96 NDLCFDTDGEYVGSCSDDGSVVINSLFTDERMKFEYHRPMKAIALDPDYARTSSRRFVTG 155
Query 148 G--KKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITN 205
G +L L + W+ ++ VLH GEG I +VKWR L+AWAN+ GVK++D + QRIT
Sbjct 156 GLAGQLYLNVKKWLG-YRDQVLHSGEGPIHAVKWRTSLVAWANDTGVKVYDASNDQRITF 214
Query 206 VPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHAS-------EMRDLPSRY 258
+ R RP++ + W+D+ L+IGWGTSVK+ ++ + M
Sbjct 215 IERPRGIPRPELLLPHIVWQDDSLLVIGWGTSVKIALIRTTQSKGANGTYKHMSMSSLNQ 274
Query 259 VEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA----------RPRLDIIQ 308
V+IV+ F+T ++ISG+AP D LV+L+Y+ E E+++ + RP + ++
Sbjct 275 VDIVASFQTSYFISGIAPFGDSLVILAYIPG-EEDGEKDFSSTIPSRQGNAQRPEVRVV- 332
Query 309 PLSETCEEISSDALTVRGFQENECRDYHL--------EYSEG------ESLFYIVSPRDV 354
+ +E+++DAL V GF+ + +DY L Y+ G E L+YIVSP+DV
Sbjct 333 --TWNNDELATDALPVHGFEHYKAKDYSLAHAPFSGSSYAGGQWAAGDEPLYYIVSPKDV 390
Query 355 VVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILD-IGLAYINHLVERGDYDI 413
V+AK RD +DHI+WLL+ +E+AL A E +Q + ++LD +G Y++HL+ Y
Sbjct 391 VIAKPRDAEDHINWLLQHGWHEKALEAVEANQG---QSELLDEVGSRYLDHLIVERKYAE 447
Query 414 AARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLE--S 471
AA C K+L +A+ WE V+ F + QL + PY+P +P L+ YE+ L S
Sbjct 448 AASLCPKLLRGSASAWERWVFHFAHLRQLPVLVPYIPTENPRLRDTAYEVALVALATNPS 507
Query 472 DYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIY 531
++ + ++ WP +Y+ + + A+ + S L + LAELY D + A +Y
Sbjct 508 FHKDLLSTVKSWPPRIYSTTPVFSAIEPQINTSSMTDPLKEALAELYVIDGQHDKAFALY 567
Query 532 LTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEEL---E 588
L D+F I KHNL ++++K++ LM D ++AV +L+ D I +VV +L
Sbjct 568 ADLMKPDLFDFIEKHNLHDAVREKVLQLMMIDCKRAVLLLIQQRDLIPPSEVVSQLIAAR 627
Query 589 DRPELQ---HVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALE 645
D+ + + H+YLH LF+ + H G+ YH+ Q+ LYA+YD LL FLR S H LEKA E
Sbjct 628 DKCDYRYFLHLYLHSLFEVNLHAGKDYHDMQVELYADYDPKMLLTFLRSSQHYTLEKAYE 687
Query 646 ICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSID 705
IC +++ ++E V++L RMGN++ AL +I+ L D+++AIEF Q D ELWE+LI S
Sbjct 688 ICVKKDLLKEQVFILGRMGNAKQALAVIINRLGDIEEAIEFVSMQQDDELWEELIQQSFH 747
Query 706 KPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILV 765
KP + LL + ++DP+ +++ + +EIP LRD LVKI+ DY + LR GC IL
Sbjct 748 KPEMVGVLLEHTVGNLDPLYIVNMLPNDLEIPRLRDRLVKIVTDYRTETSLRHGCNDILK 807
Query 766 ADSLSLLKKMHRTQMKGVLVDEE--------------NICESCLSPILPSDAAK------ 805
AD ++LL K ++ +GV + +E ++ E +S L S K
Sbjct 808 ADCVNLLVKYYKEAKRGVCLSDEVDDVSSRRGEKSVSHLGERTMS--LKSVEVKSKTRGG 865
Query 806 --------PF-----SVVVFHCRHMFHKECL 823
PF S++ F C H +H CL
Sbjct 866 GRCCICFDPFSILNVSIIAFFCCHAYHTTCL 896
>sp|P93043|VPS41_ARATH Vacuolar protein sorting-associated protein
41 homolog OS=Arabidopsis thaliana OX=3702 GN=VPS41 PE=1
SV=3
Length=980
Score = 548 bits (1411), Expect = 3e-180, Method: Compositional matrix adjust.
Identities = 319/887 (36%), Positives = 482/887 (54%), Gaps = 103/887 (12%)
Query 28 PKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKI 87
P+LKY+R+ V +L DAASC+ V + +ALGTH G V +LD+ GN ++F +
Sbjct 42 PRLKYQRMGGNVPALLSNDAASCIAVAARMIALGTHDGTVRILDLLGNQVKEFRAHTAPV 101
Query 88 NQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDC--PIKIIAVHPHFVRSSCKQFV 145
N I+ D GE++G CS+DG V + L++ +E FD P+K I++ P + + K+FV
Sbjct 102 NDINFDTEGEYIGSCSDDGSVVINSLFTDDE-KMKFDYHRPMKAISLDPDYTKKQSKRFV 160
Query 146 TGG--KKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRI 203
GG L + + W K VLH GEG I SVKWRG LIAWAN++GVK++D QR+
Sbjct 161 AGGLAGHLYMNSKKWFGN-KDQVLHSGEGPIHSVKWRGSLIAWANDVGVKVYDTAKDQRV 219
Query 204 TNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVK--ERHASEMRDLPSR---Y 258
T + + S RP+ L W+D+ L+IGWGTSVK+ S+K ++ R +
Sbjct 220 TFIEKPRGSPRPEALLPHLVWQDDTLLVIGWGTSVKIASIKSDQQQTGTFRQIQMSSLTQ 279
Query 259 VEIVSQFETEFYISGLAPLCDQLVVLSYV-------KEISEKT---EREYCARPRLDIIQ 308
V+IV+ F+T +YISG+AP D LV+L+Y+ KE S T + RP + I+
Sbjct 280 VDIVASFQTSYYISGIAPFGDSLVILAYIPIEGDGEKEFSSTTTLSRQGNAQRPEIRIV- 338
Query 309 PLSETCEEISSDALTVRGFQENECRDYHL--------EYSEG------ESLFYIVSPRDV 354
S +E++ DAL V GF+ + +DY L Y+ G E L+YIVSP+DV
Sbjct 339 --SWNNDELTMDALPVHGFEHYKAKDYSLAHAPFPGSSYAGGQWAAGDEPLYYIVSPKDV 396
Query 355 VVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILD-IGLAYINHLVERGDYDI 413
V+AK RD +DHI+WLL+ +E+AL A E S+ R +++D +G Y++HL+ Y
Sbjct 397 VIAKPRDAEDHINWLLQHGFHEKALAAVEASEG---RTELIDKVGAGYLDHLIVERKYAE 453
Query 414 AARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLE--S 471
AA C K+L +A+ WE V+ F ++ QL + PY+P +P LK +YE+ L S
Sbjct 454 AASLCPKLLRGSASAWERWVFHFAQLRQLPVLVPYMPTDNPRLKDTVYEVALVALATNPS 513
Query 472 DYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIY 531
++ + ++ WP +Y+ ++ A+ L S L + LAELY D Y A +Y
Sbjct 514 YHKELLSAVKSWPRSVYSALTVISAIEPQLNTSSMTDALKEALAELYVIDGQYQKAFSLY 573
Query 532 LTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELE--- 588
L +VF I K++L +I+ K+V LM D ++A + + N D I +VV +L
Sbjct 574 ADLLKPEVFDFIEKYSLHEAIRGKVVQLMLLDCKRATVLFIQNRDLIPPSEVVPQLLKAG 633
Query 589 ------------DRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDST 636
D ++YLH LF+ H G+ +H+ Q+ LYAEYD LLPFLR S
Sbjct 634 KNPQVLKAGKKCDSRYYLYLYLHALFEVSHDTGKDFHDMQVELYAEYDTKMLLPFLRSSQ 693
Query 637 HCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELW 696
H LEKA E+C +++F+ E V++L RMGN++ AL +I+ +L D+++A+EF Q D +LW
Sbjct 694 HYKLEKAYELCVKKDFLREQVFVLGRMGNAKQALAVIINKLGDIEEAVEFVSMQHDDDLW 753
Query 697 EDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILL 756
E+LI ++KP + LL + ++DP+ +++ + G+EIP LRD LVKI+ DY + L
Sbjct 754 EELIKQCLNKPEMVGLLLEHTVGNLDPLYIVNMVPNGLEIPRLRDRLVKIVTDYRTETSL 813
Query 757 REGCKKILVADSLSLLKKMHRTQMKGVLVDEEN--------------------------- 789
R GC IL D ++LL K +GV + E+
Sbjct 814 RHGCNDILKTDIVNLLVKCFNEARRGVCLSHEDDDSRAKREDNNRSSFSQRMVVDKSLSI 873
Query 790 -------------ICESCLSPILPSDAAKPFSVVVFHCRHMFHKECL 823
C C P+ + + +VVVF C H +H+ CL
Sbjct 874 KMTEVKSKTRGDTRCCMCFDPV----SIRGDTVVVFFCCHAYHETCL 916
>sp|Q9P7N3|VPS41_SCHPO Vacuolar protein sorting-associated protein
41 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
OX=284812 GN=vps41 PE=3 SV=2
Length=871
Score = 375 bits (964), Expect = 1e-115, Method: Compositional matrix adjust.
Identities = 228/778 (29%), Positives = 403/778 (52%), Gaps = 36/778 (5%)
Query 28 PKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKI 87
PKL YER++ D S + + G+H G +Y+ G + +K + +
Sbjct 24 PKLIYERITEKFQGCFMNDTISACAISKEHFFFGSHNGAIYIYQKNGILLRKMILHSASV 83
Query 88 NQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTG 147
+S+D E++ CS DGK+ + + + E F P+ +A+ P++ S +Q ++G
Sbjct 84 VDLSVDLESENLASCSMDGKMIISNITTRETTVHDFKRPLLSVAIDPYYSTRSSRQVLSG 143
Query 148 GK--KLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRI-- 203
G+ K++L E+ W+ K VL G + + W IAWA+++G+ ++ + +
Sbjct 144 GRAGKVVLSEKGWLGN-KDTVLQADCGAVYKISWYTTYIAWASDLGITVYSTEFGKVLGR 202
Query 204 ----TNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYV 259
+P D+I +P L W+ L+IGW + + S++ + + +LP +
Sbjct 203 LEPPKRLPNDEI------FPYQLFWQSESRLVIGWSDQIMIVSIQRSNVA--NELPK--I 252
Query 260 EIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKT-----EREYCARPRLDIIQPLSETC 314
+ + E + +SG+ L ++ L+Y+ + + T +R RP L +I +
Sbjct 253 SLQALLEIDSIVSGVLMLGFNILTLAYIANVEDFTSAIPSQRIEGCRPELRLID---SSF 309
Query 315 EEISSDALTVRGFQENECRDYHL-EYSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKK 373
+E+ DA+ + + + DYHL S +++SP D+V +ER+Q DH+ +L+ K+
Sbjct 310 KELCGDAIGLANYSRLQPSDYHLLPDPSSNSHSFVISPNDIVYVRERNQIDHVKYLVSKE 369
Query 374 KYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEV 433
Y EA+ A + + +I ++ YI HL+ +G Y A + N A WE V
Sbjct 370 MYAEAIDAVKKLPEIPPSLQISELAKKYIFHLLGKGQYKEAGMVIPSLYNDNLAEWEQWV 429
Query 434 YKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVI 493
+ F E L+ I+ +LP G+ L PL+YEMIL ++L +D F + EWP LY+ S I
Sbjct 430 FVFAENDHLEDIADFLPTGENHLSPLVYEMILAQYLATDERTFNKKLHEWPTMLYSVSTI 489
Query 494 VQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIK 553
A K++ ++ TL ++LA LY D +A +YL L + LI +HNL+ +
Sbjct 490 RNATLKKFKENQKSSTLTESLAFLYLEDNMPIDAFHLYLKLHSELCIDLILQHNLYDEAR 549
Query 554 DKIVLLMDFDSE-KAVD-------MLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRD 605
++LLM S+ K+ D ML+ + ++V+ ++ P+ + Y +
Sbjct 550 ASVLLLMLISSKGKSSDTKSAMSSMLVQHVHSFPPQEVIMQIHSVPQFLYEYFCEFELMY 609
Query 606 HHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGN 665
+ Y + ++ ++AE+DR FL ++ L+ A +IC+Q N+++E VY+L RMGN
Sbjct 610 PNSLMEYGDLKLDVFAEFDRKRFFDFLVNTQCYSLDHAAQICKQYNYLDELVYILGRMGN 669
Query 666 SRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPIL 725
++ AL +I+ EL D+ +AI + KEQ D ELW+DLI YS+DKP FI LL NIGT +
Sbjct 670 NKEALMLIINELLDIGRAIRYVKEQADRELWDDLISYSLDKPEFICTLLENIGTDENARN 729
Query 726 LIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGV 783
L+ +I G ++P+++ S+ K+L D+ Q+ L + C K+ +S+S+ K + G+
Sbjct 730 LLSKIPPGTKLPHMKKSISKLLADHQSQVQLYQSCYKLFKNESISMAIKYREQEQSGL 787
>sp|Q19954|VPS41_CAEEL Vacuolar protein sorting-associated protein
41 homolog OS=Caenorhabditis elegans OX=6239 GN=vps-41
PE=3 SV=4
Length=901
Score = 343 bits (881), Expect = 2e-103, Method: Compositional matrix adjust.
Identities = 246/855 (29%), Positives = 437/855 (51%), Gaps = 64/855 (7%)
Query 20 EEEESEEEPKLKYERLSNGVTEILQKDAA-SCMTVHDKFLALGTHYGKVYLLDVQGNITQ 78
+++E EP+ KYERL T K A + + +HDKF+A+GT G +Y+LD G
Sbjct 31 DDDEPPLEPRFKYERLKGEETLPFMKTATFTSIDLHDKFIAIGTATGLIYILDHHG--YG 88
Query 79 KFD-VSPVK-----INQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPI--KII 130
FD V P+K ++++ DE+G ++ C+ D K+ V G+ ++ T + + K I
Sbjct 89 NFDSVPPLKPHRCAVSKVKFDETGSYVLSCANDSKIVVSGV-GNDKLCCTINIQVMPKSI 147
Query 131 AVHPHFVRS-SCKQFVTGGKKLLLFERSWMNRWKSAVLHEG---EGNIRSVKWRGHLIAW 186
P F+R S F+ G + L+L+E+ M ++K++ L+ G +G I W +LIA+
Sbjct 148 YFSPDFIRQQSGHCFIMGERNLVLYEKR-MFQYKASSLYSGSERDGFIHCCSWNENLIAF 206
Query 187 ANNMGVKIFDIISKQRITNV-PRDDIS-LRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVK 244
N+ G ++++ +++ IT+V P D+ +R P W L+IGW +V + ++
Sbjct 207 TNDTGTRVYERGAERIITSVQPSHDVDRVRSSRSPPKHTWMPENNLVIGWADTVTILKIR 266
Query 245 ERHASEMRDLPSRYVEIVSQF-------------ETEFYISGLA----PLCDQLVVLSYV 287
+ + ++ ++ VS F E ++ GL D V+S V
Sbjct 267 DDDGVKKGEV--HHIFHVSMFICGISYIPESGIDNMELFLVGLQLEGEDFDDCASVISTV 324
Query 288 KEISEKTEREYCARPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESL-- 345
++ E C + +I+PL E+ S+ + N Y + L
Sbjct 325 TTLT-ALESSACTILKTSVIRPLGLKEFELQSEDMIESVKLSNHTLPYMIHGLGIPYLAT 383
Query 346 FYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAE-----ISQKNIKRHKILDIGLA 400
++I++ + +++A +D I W L+ K Y+EAL A+ +S+ ++ K+ G
Sbjct 384 YFILTTKHIIMAVPYGPEDGIRWRLKYKLYDEALDMAKHNADLLSKTDLSPKKV---GRM 440
Query 401 YINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLI 460
I + AA + I G+ WE+ V +F+E+ ++ LP G P L P
Sbjct 441 IIEGYLTGKRARAAASRLPLICGECKEEWEWAVNQFEEVKLCTLLAEVLPDGTPTLDPEC 500
Query 461 YEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKK----------DSQNKTL 510
Y+ +L L ++ + F L++ W DLY S I+ + +++ D + L
Sbjct 501 YQKVLIACLFNNVKQFRKLVQTWSPDLYMTSFIIDRTQWRIQQISKSGNLADVDETERVL 560
Query 511 LKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAVDM 570
+ LA LY Y++ Y +AL+I ++ + +F +I KH LF +KD+I LM+ +SE+A+ +
Sbjct 561 MDALAHLYLYERKYESALKILMSCQDFQIFNVIDKHQLFDLVKDQITELMNINSERALRL 620
Query 571 LLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLP 630
LLDN D + V+E++ +P+LQ YL KL R+ +G + +K + LYAEYD+ LLP
Sbjct 621 LLDNADSVEPSFVMEKIGRQPKLQLAYLTKLMSRN--EGTEFADKAVQLYAEYDQKKLLP 678
Query 631 FLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQ 690
FLR + + + KA ++C + ++EET+YLL++ GN A+KM++ E +++K I++ K+Q
Sbjct 679 FLRKNANYNVNKARKLCSDKGYIEETIYLLAKSGNHYDAVKMMVREYRNMEKVIDYCKDQ 738
Query 691 DDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDY 750
+D +LW L+ + P + L+ +DP+L++ ++ + +IPNL ++L K+L DY
Sbjct 739 NDPDLWIHLLGVVAEFPAHFSQLIIEASNCLDPLLIMDKLPDDSDIPNLSEALDKLLVDY 798
Query 751 NLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSD--AAKPFS 808
L++ C + D L + + + V V+ + C C I+ S+ K FS
Sbjct 799 TNHAELQQCCYDSTLNDLNVLTQGLISAADESVSVNIVSRCSLCAQIIINSNQETTKKFS 858
Query 809 -VVVFHCRHMFHKEC 822
+ VF C H+FH C
Sbjct 859 DIKVFKCGHIFHLAC 873
>sp|Q618H8|VPS41_CAEBR Vacuolar protein sorting-associated protein
41 homolog OS=Caenorhabditis briggsae OX=6238 GN=vps-41
PE=3 SV=1
Length=898
Score = 320 bits (821), Expect = 8e-95, Method: Compositional matrix adjust.
Identities = 252/873 (29%), Positives = 438/873 (50%), Gaps = 76/873 (9%)
Query 7 QETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAA-SCMTVHDKFLALGTHYG 65
+++G + +T++ E+E+ EP+ KYERL T K A + + +HDKF+A+GT G
Sbjct 17 EDSGDITRTTED--EDEAPLEPRFKYERLEGESTLPFMKTATFTSIDLHDKFIAIGTASG 74
Query 66 KVYLLDVQGNITQKFD-VSPVK-----INQISLDESGEHMGVCSEDGKVQVFGLYSGEEF 119
+Y+LD G FD V P+K ++++ DE+G ++ C+ D K+ V G+ ++
Sbjct 75 LIYILDHHG--YGNFDSVPPLKPHRCAVSKLKFDETGSYILSCANDSKLVVSGI-GNDKL 131
Query 120 HETFDCPI--KIIAVHPHFVRS-SCKQFVTGGKKLLLFERSWMNRWKSAVLHEG---EGN 173
T + + K I P F+R S F+ G + L+L+E+ + ++K++ L+ G +G
Sbjct 132 CCTVNIQVMPKSICFSPDFIRQQSGHCFIMGERNLVLYEKR-LFQYKASNLYSGSERDGF 190
Query 174 IRSVKWRGHLIAWANNMGVKIFDIISKQRITNV-PRDDIS-LRPDMYPCSLCWKDNVTLI 231
I W +LIA+ N+ G ++++ +++ +T+V P D+ +R P W TL+
Sbjct 191 IHCCSWNDNLIAFTNDTGTRVYERGTEKILTSVQPTHDVDRVRSSRCPPKHMWMSENTLV 250
Query 232 IGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQ-------LVVL 284
IGW +V V +K R EI F +ISG++ L LV L
Sbjct 251 IGWADTVTVLKIKGNEGM-------RKGEIHHIFHVSMFISGISYLPKNGSDYELFLVGL 303
Query 285 -----------SYVKEISEKTEREYCARPRLD--IIQPLSETCEEISSDALTVRGFQENE 331
S + ++ T E A L +I+PL E+ S+ V
Sbjct 304 QMEGEDFDDCASVMSTMTTLTAMESSATATLKTCVIRPLGLKDYELQSEDEIVNIRLSTH 363
Query 332 CRDYHLEYSEG---ESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEAL-MAAE---- 383
Y + + G S ++I++ + +++A +D I W L+ K Y EA MA E
Sbjct 364 TLPYMI-HGLGIPYLSTYFILTTKQIIMAVPYGPEDGIKWRLQYKLYTEAFEMAKEHADM 422
Query 384 ISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLK 443
+++ ++ K+ G I +E +AA I G WE+ V +F +
Sbjct 423 LAKTDVSPKKV---GRKIIEGYLESKKARVAASWLSSICGDCKEEWEWAVDRFHDAKMST 479
Query 444 AISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKK 503
+ LP P L P YE +L L ++ + F L++ W DLY S I+ + +++
Sbjct 480 LLGDVLPDSKPRLDPSAYEKVLLASLFNNVKLFRRLVQTWSPDLYMTSTIIDQTQWRIQQ 539
Query 504 DSQN----------KTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIK 553
S++ K L+ LA LY Y++ Y +AL+I + + +F +I KH LF +K
Sbjct 540 ISKSEDIEDVEEVEKILMDALAHLYLYERKYESALKILMICQDFQIFNVIDKHQLFDLVK 599
Query 554 DKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYH 613
D+I LM+ +SE+A+ +LLDN D + V+ ++ +P+LQ YL KL R+ +G +
Sbjct 600 DQISDLMNINSERALRLLLDNADSVEPSFVMAKINGQPKLQLAYLTKLMSRN--EGIEFA 657
Query 614 EKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMI 673
+K + LYA++++ LLPFL+ + + + KA ++C R FVEET++LL++ GN A+KM+
Sbjct 658 DKAVQLYADHEKKKLLPFLKKNVNYNVTKARKLCSDRGFVEETIFLLAKSGNHYEAVKMM 717
Query 674 MEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEG 733
+ E +++K I + K+Q+D +LW L+ D P + L+ +DPIL++ ++ +
Sbjct 718 VREYKNIEKVIAYCKDQNDRDLWIHLLEVVADFPTHFSQLIIEASNCLDPILIMDKLPDD 777
Query 734 MEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICES 793
++IPNL ++L K+L D+ + L++ C + D L + K V V C
Sbjct 778 VDIPNLSEALEKLLTDFTNYVELQQCCYDSTLNDLHVLTNNLMLASDKSVSVSLMTRCSL 837
Query 794 CLSPILPSDA---AKPFS-VVVFHCRHMFHKEC 822
C I+ + + F+ + VF C H+FH C
Sbjct 838 CSQVIMNTGQDMIPRKFNDIKVFKCGHIFHLTC 870
>sp|P38959|VPS41_YEAST Vacuolar protein sorting-associated protein
41 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=VPS41 PE=1 SV=2
Length=992
Score = 229 bits (585), Expect = 7e-62, Method: Compositional matrix adjust.
Identities = 220/898 (24%), Positives = 393/898 (44%), Gaps = 149/898 (17%)
Query 28 PKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFD-VSPVK 86
P LKY R+S Q+D+ S D F A GTH G ++L T F+ + +K
Sbjct 99 PLLKYTRISQLPKNFFQRDSISSCLFGDTFFAFGTHSGILHL------TTCAFEPIKTIK 152
Query 87 INQISL---DESGEHMGVCSEDGKVQVFGLYSGEEFHE-TFDCPIKIIAVHPHFVRSSCK 142
++ S+ + G++ S DG V + + + + F PI +A+H +F + +
Sbjct 153 CHRSSILCINTDGKYFATGSIDGTVIIGSMDDPQNITQYDFKRPINSVALHSNF--QASR 210
Query 143 QFVTGG--KKLLLFERSWMNRWKSAVLH--------------EGEGNIRSVKWRGHLIAW 186
FV+GG ++L +R+W+ VL+ + +G I + G LI W
Sbjct 211 MFVSGGMAGDVVLSQRNWLGNRIDIVLNKKKKKKTRKDDLSSDMKGPIMGIYTMGDLILW 270
Query 187 ANNMGVKIFDIISKQRITNVPR-----DDISLRPDMYPCSLCWKDNVTLIIGWGTSV--- 238
++ G+ D+ ++ ++ N+P + +RPD++ + + ++ ++IGWG+++
Sbjct 271 MDDDGITFCDVPTRSQLLNIPFPSRIFNVQDVRPDLFRPHVHFLESDRVVIGWGSNIWLF 330
Query 239 KVCSVKERHA------------------------------SEMRDLPSRYVEIVSQFETE 268
KV K+ ++ S R P + VE+ F
Sbjct 331 KVSFTKDSNSIKSGDSNSQSNNMSHFNPTTNIGSLLSSAASSFRGTPDKKVELECHFTVS 390
Query 269 FYISGLAPLCD-QLVVLSYVKEISE--------KTEREYCARPR----------LDIIQP 309
I+GLA D QL+ L + +I E K + + RP L I+
Sbjct 391 MLITGLASFKDDQLLCLGFDIDIEEEATIDEDMKEGKNFSKRPENLLAKGNAPELKIVDL 450
Query 310 LSETCEEISSDALTVRGFQENECRDYHL--EYSEGESLFYIVSPRDVVVAKERDQDDHID 367
+ +EI +D + ++ +++ DYHL + +Y++S D + +E DH D
Sbjct 451 FN--GDEIYNDEVIMKNYEKLSINDYHLGKHIDKTTPEYYLISSNDAIRVQELSLKDHFD 508
Query 368 WLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAA 427
W +E+K+Y +A +I + I + IGL ++N LV + D+ I +
Sbjct 509 WFMERKQYYKAW---KIGKYVIGSEERFSIGLKFLNSLVTKKDWGTLVDHLNIIFEETLN 565
Query 428 LWEYEVYKFKE---------------IGQLKAISPYLPRGDPVLKPLIYEMILHEFLESD 472
+ Y + G + I+P +P+ P L+ +Y+ +LH FL +D
Sbjct 566 SLDSNSYDVTQNVLKEWADIIEILITSGNIVEIAPLIPKK-PALRKSVYDDVLHYFLAND 624
Query 473 Y-EGFATLIREWPGDLYNNSVIVQAVRDHL----------KKDSQNKTLLKTLAELYTYD 521
F I +W L++ + + + K++ N T L LY +
Sbjct 625 MINKFHEYITKWDLKLFSVEDFEEELETRIEAASEPTASSKEEGSNITYRTELVHLYLKE 684
Query 522 KNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIV--LLMDFDSE-------------- 565
Y A+ L + +I NL D+IV +L+ + E
Sbjct 685 NKYTKAIPHLLKAKDLRALTIIKIQNLLPQYLDQIVDIILLPYKGEISHISKLSIFEIQT 744
Query 566 ---KAVDMLLDNEDKISIKKVVEELE-DRPE----LQHVYLHKLFKRDHHKGQRYHEKQ- 616
K +D+L +N IS+ ++ E E D P+ + YL K D +E Q
Sbjct 745 IFNKPIDLLFENRHTISVARIYEIFEHDCPKSFKKILFCYLIKFLDTDDSFMISPYENQL 804
Query 617 ISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQR-NFVEETVYLLSRMGNSRSALKMIME 675
I LY+EYDR +LLPFL+ + +E A+E+C + E +YL ++G ++ AL +I++
Sbjct 805 IELYSEYDRQSLLPFLQKHNNYNVESAIEVCSSKLGLYNELIYLWGKIGETKKALSLIID 864
Query 676 ELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPIL-LIHRIKEGM 734
EL + AI+F K D ELWE +I YS+DKP F +L + L +I + + +
Sbjct 865 ELKNPQLAIDFVKNWGDSELWEFMINYSLDKPNFTKAILTCSDETSEIYLKVIRGMSDDL 924
Query 735 EIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVL--VDEENI 790
+I NL+D + I+Q+ +L + +R+ I+ ++ + + + +G L VDE +I
Sbjct 925 QIDNLQDIIKHIVQENSLSLEVRDNILVIINDETKKFANEFLKIRSQGKLFQVDESDI 982
>sp|Q24314|VPS18_DROME Vacuolar protein sorting-associated protein
18 homolog OS=Drosophila melanogaster OX=7227 GN=dor PE=1
SV=3
Length=1002
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 66/278 (24%), Positives = 120/278 (43%), Gaps = 33/278 (12%)
Query 567 AVDMLLDNEDKISIKKVVEEL------EDRPELQHVYLHKLFKRDHHKGQRYHEKQISLY 620
VD L+ ++ ++K+V L E R + Q YL + + H + LY
Sbjct 646 TVDALMAQGSRLEVEKLVPTLIIMENREQREQTQR-YLEFAIYKLNTTNDAIHNFLLHLY 704
Query 621 AEYDRPNLLPFL----RDST--HCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIM 674
AE++ L+ +L RD + H + A ++C + E V+L + SA+ + +
Sbjct 705 AEHEPKLLMKYLEIQGRDESLVHYDIYYAHKVCTDLDVKEARVFLECMLRKWISAVDLAL 764
Query 675 EELHDVDKAIEFAKEQDDGE----LWEDLILYSIDKPPFITGLLNNIGTHVDPIL---LI 727
D+ A E A D + LW + + I + LN + D + L+
Sbjct 765 T--FDMKLAKETASRPSDSKIRRKLWLRIAYHDIKGTNDVKKALN-LLKECDLLRIEDLL 821
Query 728 HRIKEGMEIPNLRDSLVKILQDYN--LQILLREGCKKILVADSLSLLKKMHRTQMKGVLV 785
+ +I N ++++ L+DYN +Q L RE + D ++ ++ + + + V
Sbjct 822 PFFADFEKIDNFKEAICDALRDYNQRIQELQREMAETTEQTDRVT--AELQQLRQHSLTV 879
Query 786 DEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECL 823
+ ++ CE C +L KPF +F C H FH +CL
Sbjct 880 ESQDTCEICEMMLL----VKPF--FIFICGHKFHSDCL 911
>sp|P59015|VPS18_DANRE Vacuolar protein sorting-associated protein
18 homolog OS=Danio rerio OX=7955 GN=vps18 PE=2 SV=2
Length=974
Score = 41.6 bits (96), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 50/231 (22%), Positives = 102/231 (44%), Gaps = 25/231 (11%)
Query 608 KGQRYHEKQISLYAEYDRPNLLPFLRDS------THCPLEKALEICQQRNFVEETVYLLS 661
K + H +SLYA++ LL +L + H L+ AL +C + +++ V +
Sbjct 659 KEEAIHNYLLSLYAKHKPDALLWYLEQAGTHVSDIHYDLKYALRLCSEHGYLQACVLVYK 718
Query 662 RMGNSRSALKMIMEELHDVDKAIEFAKEQDDGE-----LWEDLILYSIDKPPFITGLLNN 716
M A+ + ++ DVD A A +D E LW + + + + + +N
Sbjct 719 IMELYEEAVDLALKV--DVDLAKSCADLPEDDEELRKKLWLKIARHVVQEEKDVKKAMNC 776
Query 717 IGT----HVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLL 772
+ + ++ IL + + I + ++++ L++YN I + + + +
Sbjct 777 LSSCNLLKIEDILPF--FPDFVTIDHFKEAICSSLEEYNKHIEELKQEMEEATESAKRIR 834
Query 773 KKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECL 823
+ + + K +V+ + C +C P+L +PF +F C HMFH +CL
Sbjct 835 EDIQEMRNKYGVVESQEKCATCDFPLL----NRPF--YLFLCGHMFHYDCL 879
>sp|Q9H270|VPS11_HUMAN Vacuolar protein sorting-associated protein
11 homolog OS=Homo sapiens OX=9606 GN=VPS11 PE=1 SV=1
Length=941
Score = 41.2 bits (95), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 53/216 (25%), Positives = 89/216 (41%), Gaps = 25/216 (12%)
Query 640 LEKALEICQQRNFVEETVYLL--SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWE 697
+KAL +CQ +F + +YL ++ M E+ V E EQD LWE
Sbjct 663 FDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPS-LWE 721
Query 698 DLILYSIDK----PPFITGLLNNIGTH--VDPILLIHRIKEG--MEIPNLRDSLVKILQD 749
+ Y K ++ +L +I + P+L++ + + +RD LV+ LQ
Sbjct 722 QALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQK 781
Query 750 YNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEE--NICESCLSPILPSDAAKPF 807
+ QI E + ++ + +++ + + + +IC S L LPS
Sbjct 782 QSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALE--LPS------ 833
Query 808 SVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNR 843
V F C H FH+ C S + A C C +NR
Sbjct 834 --VHFLCGHSFHQHCFESYSESDAD--CPTCLPENR 865
Score = 35.0 bits (79), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 25/110 (23%), Positives = 55/110 (50%), Gaps = 4/110 (4%)
Query 340 SEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGL 399
+E SL+ + V +E+D ++ L +K +E A+ A+ +++ + I +
Sbjct 335 AEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAK--SQHLDSDGLAQIFM 392
Query 400 AYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYL 449
Y +HL +G++D A ++ + +GK Y + KF + ++ ++ YL
Sbjct 393 QYGDHLYSKGNHDGAVQQYIRTIGKLEP--SYVIRKFLDAQRIHNLTAYL 440
>sp|P57232|QUEA_BUCAI S-adenosylmethionine:tRNA ribosyltransferase-isomerase
OS=Buchnera aphidicola subsp. Acyrthosiphon pisum
(strain APS) OX=107806 GN=queA PE=3 SV=1
Length=357
Score = 40.8 bits (94), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 14/39 (36%), Positives = 25/39 (64%), Gaps = 0/39 (0%)
Query 122 TFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMN 160
+FD P +I+ HP+F+RS+C+ V G ++F + + N
Sbjct 7 SFDLPKSLISFHPYFIRSTCRLMVMYGHTGMIFHKRFFN 45
>sp|B8D737|QUEA_BUCAT S-adenosylmethionine:tRNA ribosyltransferase-isomerase
OS=Buchnera aphidicola subsp. Acyrthosiphon pisum
(strain Tuc7) OX=561501 GN=queA PE=3 SV=1
Length=357
Score = 40.4 bits (93), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 14/39 (36%), Positives = 25/39 (64%), Gaps = 0/39 (0%)
Query 122 TFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMN 160
+FD P +I+ HP+F+RS+C+ V G ++F + + N
Sbjct 7 SFDLPKSLISFHPYFIRSTCRLMVMYGHTGMIFHKRFFN 45
>sp|B8D8T3|QUEA_BUCA5 S-adenosylmethionine:tRNA ribosyltransferase-isomerase
OS=Buchnera aphidicola subsp. Acyrthosiphon pisum
(strain 5A) OX=563178 GN=queA PE=3 SV=1
Length=357
Score = 40.4 bits (93), Expect = 0.052, Method: Compositional matrix adjust.
Identities = 14/39 (36%), Positives = 25/39 (64%), Gaps = 0/39 (0%)
Query 122 TFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMN 160
+FD P +I+ HP+F+RS+C+ V G ++F + + N
Sbjct 7 SFDLPKSLISFHPYFIRSTCRLMVMYGHTGMIFHKRFFN 45
>sp|Q8R307|VPS18_MOUSE Vacuolar protein sorting-associated protein
18 homolog OS=Mus musculus OX=10090 GN=Vps18 PE=1 SV=2
Length=973
Score = 41.2 bits (95), Expect = 0.054, Method: Compositional matrix adjust.
Identities = 49/229 (21%), Positives = 101/229 (44%), Gaps = 25/229 (11%)
Query 610 QRYHEKQISLYAEYDRPNLLPFLRDSTHCP------LEKALEICQQRNFVEETVYLLSRM 663
Q H +SLYA +LL +L + P L+ AL +C + V++ +
Sbjct 661 QAIHNYLLSLYARGQPASLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVL 720
Query 664 GNSRSALKMIMEELHDVDKAIEFAKEQDD---GELWEDLILYSIDKPPFITGLLNNIGTH 720
A+ + ++ D+ K E+D+ +LW + + + + + + + +
Sbjct 721 ELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC 780
Query 721 VDPILLIHRI----KEGMEIPNLRDSLVKILQDYN--LQILLREGCKKILVADSLSLLKK 774
P+L I + + + I + ++++ L+ YN +Q L RE + A + + +
Sbjct 781 --PLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQRE--MEEATASAQRIRRD 836
Query 775 MHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECL 823
+ + + V+ ++ C +C P+L +PF +F C HMFH +CL
Sbjct 837 LQELRGRYGTVEPQDKCSTCDFPLL----NRPF--YLFLCGHMFHADCL 879
>sp|Q9P253|VPS18_HUMAN Vacuolar protein sorting-associated protein
18 homolog OS=Homo sapiens OX=9606 GN=VPS18 PE=1 SV=2
Length=973
Score = 40.0 bits (92), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 49/229 (21%), Positives = 101/229 (44%), Gaps = 25/229 (11%)
Query 610 QRYHEKQISLYAEYDRPNLLPFLRDSTHCP------LEKALEICQQRNFVEETVYLLSRM 663
Q H +SLYA +LL +L + P L+ AL +C + V++ +
Sbjct 661 QAIHNYLLSLYARGRPDSLLAYLEQAGASPHRVHYDLKYALRLCAEHGHHRACVHVYKVL 720
Query 664 GNSRSALKMIMEELHDVDKAIEFAKEQDD---GELWEDLILYSIDKPPFITGLLNNIGTH 720
A+ + ++ D+ K E+D+ +LW + + + + + + + +
Sbjct 721 ELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIARHVVQEEEDVQTAMACLASC 780
Query 721 VDPILLIHRI----KEGMEIPNLRDSLVKILQDYN--LQILLREGCKKILVADSLSLLKK 774
P+L I + + + I + ++++ L+ YN +Q L RE + A + + +
Sbjct 781 --PLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQRE--MEEATASAQRIRRD 836
Query 775 MHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECL 823
+ + + V+ ++ C +C P+L +PF +F C HMFH +CL
Sbjct 837 LQELRGRYGTVEPQDKCATCDFPLL----NRPF--YLFLCGHMFHADCL 879
>sp|Q91W86|VPS11_MOUSE Vacuolar protein sorting-associated protein
11 homolog OS=Mus musculus OX=10090 GN=Vps11 PE=1 SV=3
Length=941
Score = 39.3 bits (90), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 52/216 (24%), Positives = 90/216 (42%), Gaps = 25/216 (12%)
Query 640 LEKALEICQQRNFVEETVYLL--SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWE 697
+KAL +CQ +F + +YL ++ M E+ V E EQ+ LWE
Sbjct 663 FDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVIAVCERHGEQEPS-LWE 721
Query 698 DLILYSIDK----PPFITGLLNNI--GTHVDPILLIHRIKEG--MEIPNLRDSLVKILQD 749
+ Y K ++ +L +I + + P+L++ + + +RD LV+ LQ
Sbjct 722 QALSYFARKEEDCKEYVAAVLRHIENKSLMPPLLVVQTLAHNSTATLSIIRDYLVQKLQK 781
Query 750 YNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEE--NICESCLSPILPSDAAKPF 807
+ QI E + ++ + +++ + + + +IC S L LPS
Sbjct 782 QSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALE--LPS------ 833
Query 808 SVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNR 843
V F C H FH+ C S + A C C +NR
Sbjct 834 --VHFLCGHSFHQHCFESYSESDAD--CPTCLPENR 865
Score = 35.0 bits (79), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 25/110 (23%), Positives = 55/110 (50%), Gaps = 4/110 (4%)
Query 340 SEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGL 399
+E SL+ + V +E+D ++ L +K +E A+ A+ +++ + I +
Sbjct 335 AEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAK--SQHLDSDGLAQIFM 392
Query 400 AYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYL 449
Y +HL +G++D A ++ + +GK Y + KF + ++ ++ YL
Sbjct 393 QYGDHLYSKGNHDGAVQQYIRTIGKLEP--SYVIRKFLDAQRIHNLTAYL 440
>sp|Q23194|VPS18_CAEEL Vacuolar protein sorting-associated protein
18 homolog OS=Caenorhabditis elegans OX=6239 GN=vps-18
PE=1 SV=4
Length=1026
Score = 38.5 bits (88), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 75/326 (23%), Positives = 136/326 (42%), Gaps = 58/326 (18%)
Query 558 LLMDFDSEKAVDMLLDNEDKISIKKV-------VEELEDR-PELQHVYLHKLFKRDHHKG 609
LL++ ++ + L+ N+D+IS +K+ V+ +E P ++ YL FK
Sbjct 625 LLIEHIPKQVIVYLIQNQDQISPQKLTPCLSLCVKNMEMAIPAIK--YLEAQFKGTQTIS 682
Query 610 QR------YHEKQISLYAEYDRPNLLPFL------RDSTHCPLEKALEICQQRNFVEETV 657
Q H I L A++ R LL +L R L+ A+ C+Q V
Sbjct 683 QNPQNLANLHNIYIHLMAKFRREKLLGYLESHGTIRSDLPYELDFAMRTCEQFKIEPCVV 742
Query 658 YLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGEL---WEDLILYSIDKPPFITGLL 714
YL G A++ + DVD A + A ++ E W L ++ P + +
Sbjct 743 YLFCVAGMFGDAVEKALG--FDVDLAKKCALMMEEAEANFAW----LEGMEDPAATSYIR 796
Query 715 NNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYN----LQILL-------REGCKKI 763
+ + + + + N D ++++ + N +Q LL R G K
Sbjct 797 QKLDEKAKKAIWLKIGQYYVTQENNVDKCIELINESNHLLTIQDLLPIIPKFTRVGALKP 856
Query 764 LVADSL----SLLKKMHR-----TQMKGVLVDEENICESCLSPILPSDA----AKPFSVV 810
++ D L L+K+ R T++ + D++ ++ + + PSD A+P S
Sbjct 857 IIVDFLKRNKQRLEKLERSMKEATEIASEIRDKQEKLKNRTTVVKPSDVCSHCARPISGR 916
Query 811 VFH---CRHMFHKECLPMPSMNSAAQ 833
F+ CRH FH+ECL + ++ +Q
Sbjct 917 AFNVHSCRHFFHRECLEIAMISFLSQ 942
>sp|P39702|VPS8_YEAST Vacuolar protein sorting-associated protein
8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=VPS8 PE=1 SV=2
Length=1274
Score = 38.1 bits (87), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 41/195 (21%), Positives = 78/195 (40%), Gaps = 48/195 (25%)
Query 671 KMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRI 730
K++ E + ++ +++ GE WE +++++ H D IL
Sbjct 1102 KLLQEAFLGLVRSKSSSQKDSGGEFWE---------------IMSSVLEHQDVIL----- 1141
Query 731 KEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENI 790
M++ +L+ L+ + Y L+ L E +KI+ S L+++ + +G + ++
Sbjct 1142 ---MKVQDLKQLLLNVFNTYKLERSLSELIQKIIEDSSQDLVQQYRKFLSEGWSIHTDD- 1197
Query 791 CESC--------LSPIL--------------PSDAAKPFSVVVFHCRHMFHKECLPMPSM 828
CE C L P+L D P +V+F C H FH+ CL +
Sbjct 1198 CEICGKKIWGAGLDPLLFLAWENVQRHQDMISVDLKTP--LVIFKCHHGFHQTCLENLAQ 1255
Query 829 NSAAQFCNICSAKNR 843
C IC ++
Sbjct 1256 KPDEYSCLICQTESN 1270
>sp|Q54YP4|VPS11_DICDI Vacuolar protein sorting-associated protein
11 homolog OS=Dictyostelium discoideum OX=44689 GN=vps11
PE=3 SV=1
Length=952
Score = 37.7 bits (86), Expect = 0.56, Method: Compositional matrix adjust.
Identities = 23/97 (24%), Positives = 52/97 (54%), Gaps = 4/97 (4%)
Query 632 LRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQD 691
+ D+ +E A+++C+Q + + ++L S+ LK+++E+L++ KA+++ + D
Sbjct 480 MTDNGTFDVETAIKVCRQGGYFDRALFLASKHSRHDWYLKILLEDLNEYRKALDYIQTLD 539
Query 692 DGELWEDLILYS----IDKPPFITGLLNNIGTHVDPI 724
E ++L Y + P TG+L + T+ P+
Sbjct 540 WEEADKNLKKYGKQLVSEIPEETTGVLMKLCTNYQPV 576
>sp|F4I312|VPS3_ARATH Vacuolar sorting protein 3 OS=Arabidopsis
thaliana OX=3702 GN=VPS3 PE=1 SV=2
Length=984
Score = 37.4 bits (85), Expect = 0.77, Method: Compositional matrix adjust.
Identities = 47/204 (23%), Positives = 91/204 (45%), Gaps = 18/204 (9%)
Query 605 DHHKGQRYHEKQ---ISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLS 661
D G H+ ISL+ R L FL+ S E+ LE+ + E L
Sbjct 734 DVPNGSEAHDSNVGSISLFEVDVRERLQAFLQSSDLYDPEEILELVEGSELWLEKAILYR 793
Query 662 RMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSID----KPPFITG---LL 714
R+G L+++ +L D A ++ E + + L+ +D K P LL
Sbjct 794 RIGKETLVLQILALKLEDCAAAEQYCVEIGRPDAFMQLLDMYLDPQNGKEPMFKAAVRLL 853
Query 715 NNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQD---YNLQILLREGCKKILVADS-LS 770
+N G +DP+ ++ ++ M + D+++++L+ ++ Q + + L DS L+
Sbjct 854 HNHGESLDPLQVLDKLSPDMPLKLASDTILRMLRARVHHHRQGQIVHNISRALDVDSRLA 913
Query 771 LLKKMHRTQMKGVLVDEENICESC 794
L++ R +++E++C+SC
Sbjct 914 RLEERSRHMQ----INDESLCDSC 933
>sp|Q4PH43|MTAP_MYCMD S-methyl-5'-thioadenosine phosphorylase
OS=Mycosarcoma maydis OX=5270 GN=UMAG_10466 PE=3 SV=3
Length=315
Score = 36.6 bits (83), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 44/192 (23%), Positives = 85/192 (44%), Gaps = 28/192 (15%)
Query 436 FKEIGQLKAISPYLPRGDP---VLKPLIYEMILHEF------LESD-----YEG--FAT- 478
F G +++ + GDP L+P++Y + + +D EG F+T
Sbjct 130 FFGFGDEESVVAHAGFGDPFCETLRPIVYSTVQATLASHPIKVHTDKTVVCMEGPQFSTR 189
Query 479 ----LIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTL 534
+ R W GD+ N SV+ +A L ++++ +L +A YD + + +
Sbjct 190 AESLMYRTWGGDIINMSVLPEA---KLAREAEIAYVL--IATATDYDAWRPSTAAVNVAE 244
Query 535 RHKDVFQLIHKHNLFSS-IKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPEL 593
+ + + NL ++ + D++ L +D D + AV + D+ K SI + + D+ +
Sbjct 245 VMESLKANVEASNLVTTKVLDRVWLEIDTDEKPAVKNIKDST-KFSIMTKSQVIPDKAKQ 303
Query 594 QHVYLHKLFKRD 605
+LH F RD
Sbjct 304 NLRFLHPWFARD 315
>sp|Q9ERF3|SKI8_MOUSE Superkiller complex protein 8 OS=Mus musculus
OX=10090 GN=Skic8 PE=1 SV=1
Length=305
Score = 36.6 bits (83), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 39/82 (48%), Gaps = 3/82 (4%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
++LA GTH GKV + V+ G D I I+ G+++ + DG + +F +
Sbjct 119 QYLATGTHMGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query 115 SGEEFH--ETFDCPIKIIAVHP 134
+G+ H E PI+ + P
Sbjct 179 TGKLLHTLEGHAMPIRSLTFSP 200
>sp|Q32LN7|SKI8_BOVIN Superkiller complex protein 8 OS=Bos taurus
OX=9913 GN=SKIC8 PE=2 SV=1
Length=305
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 39/82 (48%), Gaps = 3/82 (4%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
++LA GTH GKV + V+ G D I I+ G+++ + DG + +F +
Sbjct 119 QYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query 115 SGEEFH--ETFDCPIKIIAVHP 134
+G+ H E PI+ + P
Sbjct 179 TGKLLHTLEGHAMPIRSLTFSP 200
>sp|Q6P5M2|SKI8_DANRE Superkiller complex protein 8 OS=Danio rerio
OX=7955 GN=skic8 PE=2 SV=1
Length=305
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 22/82 (27%), Positives = 39/82 (48%), Gaps = 3/82 (4%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
K++A G+H GKV + V+ G D I I+ G+++ + DG + +F +
Sbjct 119 KYIATGSHLGKVNIFGVESGKKEHSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query 115 SGEEFH--ETFDCPIKIIAVHP 134
+G+ H E PI+ + P
Sbjct 179 TGKLLHTLEGHAMPIRSLTFSP 200
>sp|Q9GZS3|SKI8_HUMAN Superkiller complex protein 8 OS=Homo sapiens
OX=9606 GN=SKIC8 PE=1 SV=1
Length=305
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 39/82 (48%), Gaps = 3/82 (4%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
++LA GTH GKV + V+ G D I I+ G+++ + DG + +F +
Sbjct 119 QYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query 115 SGEEFH--ETFDCPIKIIAVHP 134
+G+ H E PI+ + P
Sbjct 179 TGKLLHTLEGHAMPIRSLTFSP 200
>sp|Q5ZJH5|SKI8_CHICK Superkiller complex protein 8 OS=Gallus
gallus OX=9031 GN=SKIC8 PE=2 SV=1
Length=305
Score = 35.8 bits (81), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 23/82 (28%), Positives = 39/82 (48%), Gaps = 3/82 (4%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
+FLA G+H GKV + V+ G D I I+ G+++ + DG + +F +
Sbjct 119 QFLATGSHVGKVNIFGVETGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query 115 SGEEFH--ETFDCPIKIIAVHP 134
+G+ H E PI+ + P
Sbjct 179 TGKLLHTLEGHAMPIRSLTFSP 200
>sp|O18388|IMB_DROME Importin subunit beta OS=Drosophila melanogaster
OX=7227 GN=Fs(2)Ket PE=1 SV=2
Length=884
Score = 36.2 bits (82), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 44/195 (23%), Positives = 80/195 (41%), Gaps = 41/195 (21%)
Query 413 IAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESD 472
+AA C +G + A WE V E + A+SPY +E I+ + LE+
Sbjct 472 VAANVCWAFIGLSDAAWEAAVTNDGETPETYALSPY------------FEYIITQLLETT 519
Query 473 --------------YEGFATLIREWPGDLYNNSVIVQ----AVRDHLKKDSQNKTLLKTL 514
Y+ +I+ P D Y ++VQ + + L + Q +T +
Sbjct 520 DRSDGAQANLRCAAYQALMDMIKNSPLDCY---LVVQRTTLVILERLNQVMQMETQINNH 576
Query 515 AELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIV--LLMDFDSEKAVDMLL 572
+ D++ N L+ L + V + +H+ + I D I+ LL F+S ++
Sbjct 577 S-----DRHQFNDLQSLLCATLQSVLRKVHEQDA-PQISDAIMTALLTMFNSSAGKSGVV 630
Query 573 DNEDKISIKKVVEEL 587
E +++ +VE L
Sbjct 631 QEEAFLAVSTLVELL 645
>sp|A4REK3|SEC13_PYRO7 Protein transport protein SEC13 OS=Pyricularia
oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507
GN=SEC13 PE=3 SV=3
Length=289
Score = 35.4 bits (80), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 43/146 (29%), Positives = 60/146 (41%), Gaps = 28/146 (19%)
Query 39 VTEILQ--KDAASCMT-VHDKF---LALGTHYGKVYLLDVQGNITQK-FDVS----PVKI 87
+TE L+ + A C+ H K+ LA + GKV++ QG QK FD + V I
Sbjct 35 LTETLKGHEGAVWCVAWAHPKYGNILASSGYDGKVFIWREQGGAWQKIFDFALHKASVNI 94
Query 88 NQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETF---------------DCPIKIIAV 132
S ESG + S DG V V H+TF P II+
Sbjct 95 VSWSPHESGCLLACASSDGHVSVLEFKDNSFDHQTFLAHGQGVNSVSWAPSTAPGSIIST 154
Query 133 HPHFVRSSCKQFVTGGKKLLLFERSW 158
+ ++ ++FVTGG L SW
Sbjct 155 NA--TPAAQRRFVTGGSDNTLKIWSW 178
>sp|Q6ZJX0|FIE2_ORYSJ Polycomb group protein FIE1 OS=Oryza sativa
subsp. japonica OX=39947 GN=FIE2 PE=1 SV=1
Length=376
Score = 35.8 bits (81), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 30/96 (31%), Positives = 43/96 (45%), Gaps = 14/96 (15%)
Query 27 EPKLKYERLSNGVTEILQK-DAASCMTVHDKF--------LALGTHYGKVYLLDVQGN-- 75
EPK K + G +ILQK C KF LA+G GKV++ +VQ +
Sbjct 270 EPKTKEQSPGEGSIDILQKYPVPECDIWFIKFSCDFHFNQLAIGNREGKVFVWEVQSSPP 329
Query 76 -ITQKFDVSPVK--INQISLDESGEHMGVCSEDGKV 108
+T + K I Q ++ G + CSEDG +
Sbjct 330 VLTARLTNPQCKSAIRQTAVSFDGSTILACSEDGSI 365
>sp|Q8AWW4|RN128_XENLA E3 ubiquitin-protein ligase RNF128 OS=Xenopus
laevis OX=8355 GN=rnf128 PE=2 SV=2
Length=404
Score = 35.4 bits (80), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 21/66 (32%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
Query 761 KKILVADSLSLLKKMH-RTQMKG--VLVDEENICESCLSPILPSDAAKPFSVVVFHCRHM 817
+K L A++ + K+ RT +G VL + + C C+ P PSD + + C H
Sbjct 227 QKRLKAEAKKAIGKLQLRTIKQGDKVLGPDGDSCAVCIEPYKPSDVVR-----ILTCNHF 281
Query 818 FHKECL 823
FHK C+
Sbjct 282 FHKNCI 287
>sp|Q90WG6|NEUA_ONCMY N-acylneuraminate cytidylyltransferase OS=Oncorhynchus
mykiss OX=8022 GN=cmas PE=2 SV=1
Length=432
Score = 35.0 bits (79), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 38/137 (28%), Positives = 63/137 (46%), Gaps = 21/137 (15%)
Query 645 EICQQRNFVEETVYLLSR--MGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLIL- 701
E+C+ +F T + R G + +M+ E D+D I++ + E +L
Sbjct 197 ELCENGSFYIYTRATIERGLQGGKWAYYEMLPEYSVDIDVDIDWP-------VAEQRVLR 249
Query 702 ---YSIDKPPFITGLLNNI-GTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLR 757
+ +DKP + LL N+ G D +LI E M N RD++ +++L R
Sbjct 250 FGYFGLDKPEVVRLLLCNVSGCLTDGRVLISVSGEEMVSVNTRDTM-------GIRMLQR 302
Query 758 EGCKKILVADSLSLLKK 774
EG + IL++ S LL K
Sbjct 303 EGVEVILISSSEDLLTK 319
>sp|Q4V7A0|SKI8_RAT Superkiller complex protein 8 OS=Rattus norvegicus
OX=10116 GN=Skic8 PE=1 SV=1
Length=305
Score = 34.7 bits (78), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 23/80 (29%), Positives = 37/80 (46%), Gaps = 3/80 (4%)
Query 58 LALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSG 116
LA GTH GKV + V+ G D I I+ G+++ + DG + +F + +G
Sbjct 121 LATGTHMGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATG 180
Query 117 EEFH--ETFDCPIKIIAVHP 134
+ H E PI+ + P
Sbjct 181 KLLHTLEGHAMPIRSLTFSP 200
>sp|Q96KV7|WDR90_HUMAN WD repeat-containing protein 90 OS=Homo
sapiens OX=9606 GN=WDR90 PE=1 SV=2
Length=1748
Score = 35.4 bits (80), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 18/59 (31%), Positives = 29/59 (49%), Gaps = 1/59 (2%)
Query 60 LGTHYGKVYLLD-VQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
+GT G ++ + +G T+ K+N++ H CSEDG V+V+ L S E
Sbjct 1410 VGTTAGTLWFVSWAEGTSTRLISGHRSKVNEVVFSPGESHCATCSEDGSVRVWALASME 1468
>sp|Q10322|DMA1_SCHPO Probable E3 ubiquitin-protein ligase dma1
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812
GN=dma1 PE=1 SV=1
Length=267
Score = 34.7 bits (78), Expect = 3.3, Method: Compositional matrix adjust.
Identities = 32/143 (22%), Positives = 59/143 (41%), Gaps = 19/143 (13%)
Query 709 FITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYN-----------LQILLR 757
+I + ++ GT ++ + L K P + ++++ DY ++ L
Sbjct 99 YIQDMGSSSGTFLNHVRLSPPSKTSKPYPISNNDILQLGADYRGGHEVNYRCVRARVELN 158
Query 758 EGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHM 817
K L +L+ K+M + G C CL P+LP A + V C H
Sbjct 159 NSWKIKLSPYNLNEFKRMQELVLCGSSESGPPECCICLMPVLPCQA-----LFVAPCSHS 213
Query 818 FHKECLPMPSMNSAAQF--CNIC 838
+H +C+ P++N + + C IC
Sbjct 214 YHYKCI-RPTLNESHPYFSCFIC 235
>sp|Q9VEA2|VPS39_DROME Vacuolar protein sorting-associated protein
39 homolog OS=Drosophila melanogaster OX=7227 GN=Vps39
PE=1 SV=1
Length=876
Score = 35.0 bits (79), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 60/281 (21%), Positives = 111/281 (40%), Gaps = 55/281 (20%)
Query 554 DKIVLLMDFDSEKAVDMLLDNEDKISI---KKVVEELEDRPELQHVYLHKLFKRDHHKGQ 610
D+++ + K +D + + I + V+ E +D L H L K
Sbjct 577 DELIEVESLPRAKVLDFFISKHKALVIPYLEHVITEWKDGNTLLHNVLLK---------- 626
Query 611 RYHEKQISLYAEYDR----PNLLPF-------LRDSTHCPLEKALEICQQRNFVEETVYL 659
+Y EK L A+ ++ P L+P L +S ++ LE +EE +
Sbjct 627 QYREKVQRLLAQQEKGEEVPELIPMRAKLYKMLEESNDYSPDRLLEEFPTNILLEERALI 686
Query 660 LSRMGNSRSALKMIMEELHDVDKAIEFAKE--QDDGELWEDLILYSIDKP--PFITG--- 712
L R+ + L + + L DV KA +A+ ++D ++ LI + P P G
Sbjct 687 LGRLKKHDNVLSIYIHVLGDVAKATAYAEAHYKEDKHIFHTLIKCILIPPTQPLYDGVPL 746
Query 713 --------------LLNNIGTHVDPILLIHRIKEGMEIPN----LRDSLVKILQD-YNLQ 753
+LN T +DP + + + M +P L S+ K++ D + +Q
Sbjct 747 HPDFSQVNREVALEILNTHATRIDPFEIFEHLPDDMPMPQLEKYLEKSIRKMMADKHEMQ 806
Query 754 ILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESC 794
++ C L A+S L + + ++E ++C C
Sbjct 807 MM----C-GFLEAESTRLENALEEQRNISFELNESSVCSEC 842
>sp|Q9SUS5|RHA1B_ARATH E3 ubiquitin-protein ligase RHA1B OS=Arabidopsis
thaliana OX=3702 GN=RHA1B PE=2 SV=1
Length=157
Score = 33.1 bits (74), Expect = 4.8, Method: Composition-based stats.
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 6/61 (10%)
Query 783 VLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKN 842
+L D E+ C CLS + D + C H+FH CL ++ C IC +N
Sbjct 77 LLTDPEDCCTVCLSDFVSDDKIRQLP----KCGHVFHHRCLDRWIVDCNKITCPIC--RN 130
Query 843 R 843
R
Sbjct 131 R 131
>sp|Q6ZPG2|WDR90_MOUSE WD repeat-containing protein 90 OS=Mus
musculus OX=10090 GN=Wdr90 PE=1 SV=2
Length=1874
Score = 34.7 bits (78), Expect = 4.9, Method: Compositional matrix adjust.
Identities = 17/59 (29%), Positives = 28/59 (47%), Gaps = 1/59 (2%)
Query 60 LGTHYGKVYLLD-VQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
+GT G ++ + +G T+ K+N++ H C EDG V+V+ L S E
Sbjct 1536 VGTTAGTIWYISWTEGTSTRLISGHRTKVNEVVFSPGESHCATCGEDGSVRVWSLASME 1594
>sp|Q9SJ40|VPS11_ARATH Vacuolar protein-sorting-associated protein
11 homolog OS=Arabidopsis thaliana OX=3702 GN=VPS11 PE=1
SV=1
Length=932
Score = 34.7 bits (78), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 13/48 (27%), Positives = 30/48 (63%), Gaps = 0/48 (0%)
Query 640 LEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFA 687
+E A+ +C+ N+ E +Y+ + G LK+++E+L + D+A+++
Sbjct 461 VETAIRVCRAANYHEHAMYVAKKAGKHEWYLKILLEDLGNYDEALQYV 508
>sp|Q29HG9|LST8_DROPS Protein LST8 homolog OS=Drosophila pseudoobscura
pseudoobscura OX=46245 GN=GA15597 PE=3 SV=1
Length=315
Score = 33.9 bits (76), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 13/145 (9%)
Query 55 DKFLALGTHYGKVYLLDVQGNITQ---KFDVSPVKINQISLDESGEHMGVCSEDGKVQVF 111
DK Y + L D++ N T FD + ++ E G M ED V+++
Sbjct 46 DKTRLAACGYQCIRLYDLESNCTAPVINFDGVQKNVTRLGFQEDGNWMFTAGEDHHVRIW 105
Query 112 GLYSG-EEFHETFDC--PIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLH 168
+ S FDC P+ +HP+ V + G + +F + ++
Sbjct 106 DMISAPPHCSRVFDCESPVNAACLHPNQV-----EIGMGSQNGNVFLWDVKSEKHECIVP 160
Query 169 EGEGNIRSVKWR--GHLIAWANNMG 191
E + +I+ V GH +A ANN G
Sbjct 161 EVDASIQDVAISPDGHYLAAANNKG 185
>sp|P73594|Y1409_SYNY3 WD repeat-containing protein slr1409 OS=Synechocystis
sp. (strain ATCC 27184 / PCC 6803 / Kazusa) OX=1111708
GN=slr1409 PE=1 SV=1
Length=326
Score = 33.9 bits (76), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 19/92 (21%), Positives = 43/92 (47%), Gaps = 3/92 (3%)
Query 32 YERLSNGVTEILQKDAASCMTVHDKFLALGT--HYGKVYLLDVQGNITQKFDVSPVKINQ 89
+ R + +L+ A + H + L + + G ++L++ G I ++ +IN
Sbjct 158 FTRQGQEIASVLKSGTARNLAYHPQGLLIASVSDSGSLHLINPNGKIEREISTGQGRINN 217
Query 90 ISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE 121
++ +GE + +G +++ L +GE HE
Sbjct 218 VNFSPNGEQLLTSGINGSAKLWNL-AGELIHE 248
>sp|A1S3I3|HLDE_SHEAM Bifunctional protein HldE OS=Shewanella
amazonensis (strain ATCC BAA-1098 / SB2B) OX=326297 GN=hldE
PE=3 SV=1
Length=476
Score = 33.9 bits (76), Expect = 8.3, Method: Compositional matrix adjust.
Identities = 24/93 (26%), Positives = 43/93 (46%), Gaps = 6/93 (6%)
Query 68 YLLDVQGNITQKFDVSPVKINQISLDESGEH---MGVCSEDGKVQVFGLYSGEEFHETFD 124
Y + G I+ + V V+INQI G + + + GKVQ+ GL ++ +
Sbjct 24 YWVGPTGRISPEAPVPVVRINQIEDRPGGAANVALNIAALGGKVQLSGLVGQDDTADALT 83
Query 125 CPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERS 157
++ + V PH++ K +T KL + R+
Sbjct 84 RGVQALGVEPHWLVVEDKPTIT---KLRVLSRN 113
>sp|Q9W328|LST8_DROME Protein LST8 homolog OS=Drosophila melanogaster
OX=7227 GN=Lst8 PE=1 SV=2
Length=313
Score = 33.5 bits (75), Expect = 9.2, Method: Compositional matrix adjust.
Identities = 21/94 (22%), Positives = 43/94 (46%), Gaps = 8/94 (9%)
Query 48 ASCMTVHDKFLALGTHYGKVYLLDVQG----NITQKFDVSPVKINQISLDESGEHMGVCS 103
A+C+ + +A+G+ G V+L DV+ I + D S I +++ G ++ +
Sbjct 128 AACLHPNQVEIAMGSQNGSVFLWDVKSERHERIVPEVDAS---IQDVAISPDGRYLAAAN 184
Query 104 EDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFV 137
G ++ L S ++ T P + I H ++
Sbjct 185 NKGNCYIWSLTSQDQKMSTLR-PNRKIPAHSRYI 217
Lambda K H a alpha
0.319 0.136 0.404 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 98193838406
Results from round 2
Query= sp|P49754|VPS41_HUMAN Vacuolar protein sorting-associated protein 41
homolog OS=Homo sapiens OX=9606 GN=VPS41 PE=1 SV=3
Length=854
Score E
Sequences producing significant alignments: (Bits) Value
Sequences used in model and found again:
sp|P49754|VPS41_HUMAN Vacuolar protein sorting-associated protein... 1220 0.0
sp|Q5KU39|VPS41_MOUSE Vacuolar protein sorting-associated protein... 1207 0.0
sp|E7F590|VPS41_DANRE Vacuolar protein sorting-associated protein... 1185 0.0
sp|P93231|VPS41_SOLLC Vacuolar protein sorting-associated protein... 977 0.0
sp|P93043|VPS41_ARATH Vacuolar protein sorting-associated protein... 958 0.0
sp|Q7PL76|VPS41_DROME Vacuolar protein sorting-associated protein... 920 0.0
sp|Q19954|VPS41_CAEEL Vacuolar protein sorting-associated protein... 882 0.0
sp|Q618H8|VPS41_CAEBR Vacuolar protein sorting-associated protein... 874 0.0
sp|Q9P7N3|VPS41_SCHPO Vacuolar protein sorting-associated protein... 842 0.0
sp|P38959|VPS41_YEAST Vacuolar protein sorting-associated protein... 711 0.0
sp|Q24314|VPS18_DROME Vacuolar protein sorting-associated protein... 231 3e-62
Sequences not found previously or not previously below threshold:
sp|P59015|VPS18_DANRE Vacuolar protein sorting-associated protein... 140 9e-33
sp|Q8R307|VPS18_MOUSE Vacuolar protein sorting-associated protein... 125 3e-28
sp|Q9P253|VPS18_HUMAN Vacuolar protein sorting-associated protein... 125 4e-28
sp|F4IDS7|VPS18_ARATH Vacuolar sorting protein 18 OS=Arabidopsis ... 104 2e-21
sp|Q23194|VPS18_CAEEL Vacuolar protein sorting-associated protein... 95.9 7e-19
sp|Q9VRX2|VPS8_DROME Vacuolar protein sorting-associated protein ... 89.4 8e-17
sp|Q9H270|VPS11_HUMAN Vacuolar protein sorting-associated protein... 88.6 1e-16
sp|Q8R5L3|VPS39_MOUSE Vam6/Vps39-like protein OS=Mus musculus OX=... 88.6 1e-16
sp|Q91W86|VPS11_MOUSE Vacuolar protein sorting-associated protein... 87.5 3e-16
sp|Q96JC1|VPS39_HUMAN Vam6/Vps39-like protein OS=Homo sapiens OX=... 84.4 2e-15
sp|Q0P5W1|VPS8_MOUSE Vacuolar protein sorting-associated protein ... 81.3 2e-14
sp|Q8N3P4|VPS8_HUMAN Vacuolar protein sorting-associated protein ... 78.2 3e-13
sp|Q8WUH2|TGFA1_HUMAN Transforming growth factor-beta receptor-as... 73.6 5e-12
sp|O74925|PEP3_SCHPO Vacuolar membrane protein pep3 OS=Schizosacc... 71.3 3e-11
sp|Q3UR70|TGFA1_MOUSE Transforming growth factor-beta receptor-as... 70.1 7e-11
sp|F4I312|VPS3_ARATH Vacuolar sorting protein 3 OS=Arabidopsis th... 70.1 7e-11
sp|A4IG72|TGFA1_DANRE Transforming growth factor-beta receptor-as... 69.7 7e-11
sp|Q9VEA2|VPS39_DROME Vacuolar protein sorting-associated protein... 68.6 2e-10
sp|P27801|PEP3_YEAST Vacuolar membrane protein PEP3 OS=Saccharomy... 64.0 5e-09
sp|Q9SJ40|VPS11_ARATH Vacuolar protein-sorting-associated protein... 62.8 1e-08
sp|A7MB11|TGFA1_BOVIN Transforming growth factor-beta receptor-as... 60.9 5e-08
sp|Q07468|VAM6_YEAST Vacuolar morphogenesis protein 6 OS=Saccharo... 58.6 2e-07
sp|Q54YP4|VPS11_DICDI Vacuolar protein sorting-associated protein... 58.2 3e-07
sp|P39702|VPS8_YEAST Vacuolar protein sorting-associated protein ... 58.2 3e-07
sp|Q6P5M2|SKI8_DANRE Superkiller complex protein 8 OS=Danio rerio... 56.6 3e-07
sp|B7FNU7|LIS1_PHATC Lissencephaly-1 homolog OS=Phaeodactylum tri... 55.9 9e-07
sp|Q10161|CLH_SCHPO Probable clathrin heavy chain OS=Schizosaccha... 55.1 3e-06
sp|P34574|CLH_CAEEL Probable clathrin heavy chain 1 OS=Caenorhabd... 54.3 5e-06
sp|Q10051|PRP19_CAEEL Pre-mRNA-processing factor 19 OS=Caenorhabd... 53.2 8e-06
sp|P74442|Y143_SYNY3 Uncharacterized WD repeat-containing protein... 53.2 1e-05
sp|Q09600|VPS11_CAEEL Vacuolar protein sorting-associated protein... 52.8 1e-05
sp|Q1ZXS5|VPS39_CAEEL Vacuolar protein sorting-associated protein... 52.0 2e-05
sp|Q0WLB5|CLAH2_ARATH Clathrin heavy chain 2 OS=Arabidopsis thali... 51.6 3e-05
sp|Q9P6N4|PEP5_SCHPO E3 ubiquitin-protein ligase pep5 OS=Schizosa... 51.2 4e-05
sp|Q0WNJ6|CLAH1_ARATH Clathrin heavy chain 1 OS=Arabidopsis thali... 50.9 5e-05
sp|P53675|CLH2_HUMAN Clathrin heavy chain 2 OS=Homo sapiens OX=96... 50.1 9e-05
sp|G0SC29|NLE1_CHATD Ribosome assembly protein 4 OS=Chaetomium th... 49.7 9e-05
sp|Q5FVN8|WSDU1_RAT WD repeat, SAM and U-box domain-containing pr... 48.9 1e-04
sp|Q9W328|LST8_DROME Protein LST8 homolog OS=Drosophila melanogas... 48.5 1e-04
sp|Q6GMD2|SKI8_XENLA Superkiller complex protein 8 OS=Xenopus lae... 48.2 2e-04
sp|B4N984|WDR55_DROWI WD repeat-containing protein 55 homolog OS=... 48.2 3e-04
sp|Q2RBN7|CLH1_ORYSJ Clathrin heavy chain 1 OS=Oryza sativa subsp... 48.9 3e-04
sp|Q2QYW2|CLH2_ORYSJ Clathrin heavy chain 2 OS=Oryza sativa subsp... 48.5 3e-04
sp|D3Z7A5|DAW1_MOUSE Dynein assembly factor with WD repeat domain... 48.2 3e-04
sp|B4JSW8|WDR55_DROGR WD repeat-containing protein 55 homolog OS=... 48.2 3e-04
sp|Q5BK30|DAW1_RAT Dynein assembly factor with WD repeat domains ... 47.8 3e-04
sp|P29742|CLH_DROME Clathrin heavy chain OS=Drosophila melanogast... 48.2 4e-04
sp|P22137|CLH_YEAST Clathrin heavy chain OS=Saccharomyces cerevis... 48.2 4e-04
sp|A0AUS0|WSDU1_DANRE WD repeat, SAM and U-box domain-containing ... 47.4 5e-04
sp|B4KE10|WDR55_DROMO WD repeat-containing protein 55 homolog OS=... 47.4 5e-04
sp|Q4V7A0|SKI8_RAT Superkiller complex protein 8 OS=Rattus norveg... 46.6 5e-04
sp|P11442|CLH1_RAT Clathrin heavy chain 1 OS=Rattus norvegicus OX... 47.8 6e-04
sp|P49951|CLH1_BOVIN Clathrin heavy chain 1 OS=Bos taurus OX=9913... 47.8 6e-04
sp|Q00610|CLH1_HUMAN Clathrin heavy chain 1 OS=Homo sapiens OX=96... 47.8 6e-04
sp|Q5ZJH5|SKI8_CHICK Superkiller complex protein 8 OS=Gallus gall... 46.6 6e-04
sp|Q68FD5|CLH1_MOUSE Clathrin heavy chain 1 OS=Mus musculus OX=10... 47.4 6e-04
sp|Q9D0I6|WSDU1_MOUSE WD repeat, SAM and U-box domain-containing ... 47.0 6e-04
sp|Q9GZS3|SKI8_HUMAN Superkiller complex protein 8 OS=Homo sapien... 46.2 7e-04
sp|Q8L5Y0|VPS39_ARATH Vacuolar sorting protein 39 OS=Arabidopsis ... 47.0 7e-04
sp|Q9ERF3|SKI8_MOUSE Superkiller complex protein 8 OS=Mus musculu... 46.2 8e-04
sp|Q32LN7|SKI8_BOVIN Superkiller complex protein 8 OS=Bos taurus ... 46.2 8e-04
sp|B3M1G0|WDR55_DROAN WD repeat-containing protein 55 homolog OS=... 46.6 0.001
sp|Q6PBD6|SKI8_XENTR Superkiller complex protein 8 OS=Xenopus tro... 45.5 0.001
sp|Q5ZMC3|WSDU1_CHICK WD repeat, SAM and U-box domain-containing ... 45.5 0.002
sp|Q54S59|SKI8_DICDI Superkiller complex protein 8 OS=Dictyosteli... 44.7 0.002
sp|C5MIB1|RTC1_CANTT Restriction of telomere capping protein 1 OS... 45.5 0.003
sp|G5EEG7|SMU1_CAEEL Smu-1 suppressor of mec-8 and unc-52 protein... 44.7 0.003
sp|B4M4W4|WDR55_DROVI WD repeat-containing protein 55 homolog OS=... 44.7 0.003
sp|O13955|VAM6_SCHPO Vacuolar morphogenesis protein 6 OS=Schizosa... 44.7 0.004
sp|Q26544|WSL17_SCHMA WD repeat-containing protein SL1-17 OS=Schi... 43.9 0.004
sp|Q4R8E7|DAW1_MACFA Dynein assembly factor with WD repeat domain... 44.3 0.004
sp|B4PU14|WDR55_DROYA WD repeat-containing protein 55 homolog OS=... 44.3 0.004
sp|Q8N9V3|WSDU1_HUMAN WD repeat, SAM and U-box domain-containing ... 43.9 0.006
sp|Q8W117|SMU1_ARATH Suppressor of mec-8 and unc-52 protein homol... 43.9 0.006
sp|Q29HG9|LST8_DROPS Protein LST8 homolog OS=Drosophila pseudoobs... 43.5 0.006
sp|P49695|PKWA_THECU Probable serine/threonine-protein kinase Pkw... 43.9 0.006
sp|Q8T088|WDR55_DROME WD repeat-containing protein 55 homolog OS=... 43.5 0.007
sp|Q297N8|HPS5_DROPS BLOC-2 complex member HPS5 homolog OS=Drosop... 43.9 0.007
sp|Q5ZMA2|PRP19_CHICK Pre-mRNA-processing factor 19 OS=Gallus gal... 43.5 0.007
sp|P0CS46|PFS2_CRYNJ Polyadenylation factor subunit 2 OS=Cryptoco... 43.9 0.007
sp|P0CS47|PFS2_CRYNB Polyadenylation factor subunit 2 OS=Cryptoco... 43.9 0.007
sp|Q9VHN9|HPS5_DROME BLOC-2 complex member HPS5 homolog OS=Drosop... 43.5 0.008
sp|Q9JMJ4|PRP19_RAT Pre-mRNA-processing factor 19 OS=Rattus norve... 43.2 0.009
sp|Q99KP6|PRP19_MOUSE Pre-mRNA-processing factor 19 OS=Mus muscul... 43.2 0.009
sp|Q9UMS4|PRP19_HUMAN Pre-mRNA-processing factor 19 OS=Homo sapie... 43.2 0.009
sp|Q08E38|PRP19_BOVIN Pre-mRNA-processing factor 19 OS=Bos taurus... 43.2 0.009
sp|A4REK3|SEC13_PYRO7 Protein transport protein SEC13 OS=Pyricula... 42.8 0.010
sp|Q9LFI1|PP280_ARATH Pentatricopeptide repeat-containing protein... 43.2 0.011
sp|Q7KWK5|PRP19_DICDI Pre-mRNA-processing factor 19 OS=Dictyostel... 43.2 0.011
sp|Q4P9P9|LIS1_MYCMD Nuclear distribution protein PAC1 OS=Mycosar... 43.2 0.011
sp|B3P4F8|WDR55_DROER WD repeat-containing protein 55 homolog OS=... 43.2 0.011
sp|Q8N136|DAW1_HUMAN Dynein assembly factor with WD repeat domain... 42.8 0.012
sp|A8X8C6|TG125_CAEBR WD repeat-containing protein wdr-5.1 OS=Cae... 42.8 0.012
sp|B4QTL6|WDR55_DROSI WD repeat-containing protein 55 homolog OS=... 42.8 0.013
sp|P25870|CLH_DICDI Clathrin heavy chain OS=Dictyostelium discoid... 43.2 0.013
sp|Q9FKT5|THOC3_ARATH THO complex subunit 3 OS=Arabidopsis thalia... 42.4 0.013
sp|B6GZD3|LIS12_PENRW Nuclear distribution protein nudF 2 OS=Peni... 42.8 0.014
sp|A9V790|LIS1_MONBE Lissencephaly-1 homolog OS=Monosiga brevicol... 42.4 0.014
sp|A8XXC7|WDFY2_CAEBR WD repeat and FYVE domain-containing protei... 41.6 0.024
sp|Q9VU65|POC1_DROME POC1 centriolar protein homolog OS=Drosophil... 41.6 0.025
sp|Q54D08|LST8_DICDI Protein LST8 homolog OS=Dictyostelium discoi... 41.2 0.028
sp|F6ZT52|POC1B_XENTR POC1 centriolar protein homolog B OS=Xenopu... 41.6 0.032
sp|Q10282|GBB_SCHPO Guanine nucleotide-binding protein subunit be... 40.8 0.039
sp|Q6CB13|MDV1_YARLI Mitochondrial division protein 1 OS=Yarrowia... 40.8 0.050
sp|Q5Z8R1|IPI1_ORYSJ E3 ubiquitin-protein ligase IPI1 OS=Oryza sa... 40.8 0.051
sp|Q8SX81|VPS11_DROME Vacuolar protein sorting-associated protein... 41.2 0.053
sp|Q93847|WDR52_CAEEL WD repeat-containing protein wdr-5.2 OS=Cae... 40.5 0.057
sp|Q55563|Y163_SYNY3 Uncharacterized WD repeat-containing protein... 40.8 0.060
sp|P87295|PEP5L_SCHPO Pep5-like zinc finger protein C16A10.03c OS... 40.5 0.074
sp|Q17963|WDR51_CAEEL WD repeat-containing protein wdr-5.1 OS=Cae... 40.1 0.075
sp|Q59WJ4|PFS2_CANAL Polyadenylation factor subunit 2 OS=Candida ... 40.5 0.078
sp|F4IIK6|LST82_ARATH Non-functional target of rapamycin complex ... 39.7 0.088
sp|Q2KJH4|WDR1_BOVIN WD repeat-containing protein 1 OS=Bos taurus... 40.1 0.088
sp|Q7T394|LIS1A_DANRE Lissencephaly-1 homolog A OS=Danio rerio OX... 40.1 0.091
sp|P87177|YB1C_SCHPO Uncharacterized WD repeat-containing protein... 40.1 0.095
sp|C3XVT5|LIS1_BRAFL Lissencephaly-1 homolog OS=Branchiostoma flo... 39.7 0.100
sp|Q00808|HETE1_PODAS Vegetative incompatibility protein HET-E-1 ... 40.1 0.10
sp|Q54Y96|SMU1_DICDI WD40 repeat-containing protein smu1 OS=Dicty... 40.1 0.10
sp|P87139|YDM9_SCHPO Uncharacterized RING finger protein C57A7.09... 39.7 0.11
sp|Q15542|TAF5_HUMAN Transcription initiation factor TFIID subuni... 40.1 0.11
sp|Q8C092|TAF5_MOUSE Transcription initiation factor TFIID subuni... 40.1 0.11
sp|Q20168|COPB2_CAEEL Probable coatomer subunit beta' OS=Caenorha... 40.1 0.11
sp|D3BUN1|LIS1_HETP5 Lissencephaly-1 homolog OS=Heterostelium pal... 39.7 0.11
sp|O74184|WAT1_SCHPO Target of rapamycin complex subunit wat1 OS=... 39.3 0.12
sp|Q9CWU9|NUP37_MOUSE Nucleoporin Nup37 OS=Mus musculus OX=10090 ... 39.3 0.12
sp|O62621|COPB2_DROME Coatomer subunit beta' OS=Drosophila melano... 39.7 0.13
sp|Q9AYE4|LST8_ORYSJ Target of rapamycin complex subunit LST8 OS=... 38.9 0.14
sp|Q9BVA0|KTNB1_HUMAN Katanin p80 WD40 repeat-containing subunit ... 39.3 0.15
sp|Q8BG40|KTNB1_MOUSE Katanin p80 WD40 repeat-containing subunit ... 39.3 0.15
sp|A0A1L8GLK3|RFW3L_XENLA E3 ubiquitin-protein ligase rfwd3.L OS=... 39.7 0.15
sp|Q4V7Y7|KTNB1_XENLA Katanin p80 WD40 repeat-containing subunit ... 39.3 0.16
sp|Q9SUS5|RHA1B_ARATH E3 ubiquitin-protein ligase RHA1B OS=Arabid... 37.4 0.17
sp|A0A974CYQ5|RFW3S_XENLA E3 ubiquitin-protein ligase rfwd3.S OS=... 39.3 0.18
sp|Q6ZJX0|FIE2_ORYSJ Polycomb group protein FIE1 OS=Oryza sativa ... 38.9 0.18
sp|P87053|POF1_SCHPO F-box/WD repeat-containing protein pof1 OS=S... 39.3 0.19
sp|O62471|QUI1_CAEEL Protein qui-1 OS=Caenorhabditis elegans OX=6... 39.3 0.19
sp|Q9UUG8|TUP12_SCHPO Transcriptional repressor tup12 OS=Schizosa... 39.3 0.19
sp|O74319|TAF73_SCHPO Transcription initiation factor TFIID subun... 38.9 0.21
sp|Q8NFH4|NUP37_HUMAN Nucleoporin Nup37 OS=Homo sapiens OX=9606 G... 38.5 0.22
sp|Q6BVZ3|PFS2_DEBHA Polyadenylation factor subunit 2 OS=Debaryom... 38.9 0.24
sp|Q10322|DMA1_SCHPO Probable E3 ubiquitin-protein ligase dma1 OS... 38.1 0.25
sp|P73595|Y1410_SYNY3 Uncharacterized WD repeat-containing protei... 38.5 0.25
sp|Q5AGM0|HIR2_CANAL Protein HIR2 OS=Candida albicans (strain SC5... 38.9 0.26
sp|Q0J3D9|COPA3_ORYSJ Coatomer subunit alpha-3 OS=Oryza sativa su... 38.9 0.26
sp|Q9AUR8|COPA1_ORYSJ Coatomer subunit alpha-1 OS=Oryza sativa su... 38.9 0.26
sp|Q9ZT50|RHA2A_ARATH E3 ubiquitin-protein ligase RHA2A OS=Arabid... 37.0 0.27
sp|O88342|WDR1_MOUSE WD repeat-containing protein 1 OS=Mus muscul... 38.5 0.28
sp|O93277|WDR1_CHICK WD repeat-containing protein 1 OS=Gallus gal... 38.5 0.28
sp|A8NEG8|LIS1_COPC7 Nuclear distribution protein PAC1 OS=Coprino... 38.1 0.30
sp|Q90ZL4|LIS1_XENLA Lissencephaly-1 homolog OS=Xenopus laevis OX... 38.1 0.31
sp|Q7ZUV2|KTNB1_DANRE Katanin p80 WD40 repeat-containing subunit ... 38.5 0.31
sp|Q6NZH4|LIS1_XENTR Lissencephaly-1 homolog OS=Xenopus tropicali... 38.1 0.31
sp|Q54DS8|SEC13_DICDI Protein SEC13 homolog OS=Dictyostelium disc... 37.8 0.32
sp|Q6CP71|PFS2_KLULA Polyadenylation factor subunit 2 OS=Kluyvero... 38.1 0.32
sp|Q9H6Y7|RN167_HUMAN E3 ubiquitin-protein ligase RNF167 OS=Homo ... 38.1 0.33
sp|O82239|RFI2_ARATH E3 ubiquitin-protein ligase RFI2 OS=Arabidop... 38.1 0.33
sp|P73594|Y1409_SYNY3 WD repeat-containing protein slr1409 OS=Syn... 38.1 0.33
sp|B7PS00|LIS1_IXOSC Lissencephaly-1 homolog OS=Ixodes scapularis... 38.1 0.36
sp|Q93794|SEL10_CAEEL F-box/WD repeat-containing protein sel-10 O... 38.1 0.37
sp|Q9DC22|DCAF6_MOUSE DDB1- and CUL4-associated factor 6 OS=Mus m... 38.1 0.39
sp|Q9W7F2|WDR1A_XENLA WD repeat-containing protein 1-A OS=Xenopus... 38.1 0.39
sp|Q28D01|WDR26_XENTR WD repeat-containing protein 26 OS=Xenopus ... 38.1 0.39
sp|Q99M63|SMU1_RAT WD40 repeat-containing protein SMU1 OS=Rattus ... 38.1 0.41
sp|Q3UKJ7|SMU1_MOUSE WD40 repeat-containing protein SMU1 OS=Mus m... 38.1 0.41
sp|Q2TAY7|SMU1_HUMAN WD40 repeat-containing protein SMU1 OS=Homo ... 38.1 0.41
sp|Q76B40|SMU1_CRIGR WD40 repeat-containing protein SMU1 OS=Crice... 38.1 0.41
sp|Q2TBS9|SMU1_BOVIN WD40 repeat-containing protein SMU1 OS=Bos t... 38.1 0.41
sp|Q6P4J8|SMU1_XENTR WD40 repeat-containing protein SMU1 OS=Xenop... 38.1 0.41
sp|Q6NRT3|SMU1_XENLA WD40 repeat-containing protein SMU1 OS=Xenop... 38.1 0.41
sp|O61585|KTNB1_STRPU Katanin p80 WD40 repeat-containing subunit ... 38.1 0.42
sp|Q7PS24|CIAO1_ANOGA Probable cytosolic iron-sulfur protein asse... 37.8 0.43
sp|Q5R9B8|DCAF6_PONAB DDB1- and CUL4-associated factor 6 OS=Pongo... 38.1 0.43
sp|Q58WW2|DCAF6_HUMAN DDB1- and CUL4-associated factor 6 OS=Homo ... 38.1 0.43
sp|Q75AV4|PFS2_EREGS Polyadenylation factor subunit 2 OS=Eremothe... 37.8 0.44
sp|Q6NV31|WDR82_DANRE WD repeat-containing protein 82 OS=Danio re... 37.4 0.46
sp|Q8W4Q5|RIN3_ARATH E3 ubiquitin protein ligase RIN3 OS=Arabidop... 37.8 0.47
sp|Q8K450|SPG16_MOUSE Sperm-associated antigen 16 protein OS=Mus ... 37.8 0.47
sp|O75083|WDR1_HUMAN WD repeat-containing protein 1 OS=Homo sapie... 37.8 0.47
sp|Q9Y7K5|YGI3_SCHPO Uncharacterized WD repeat-containing protein... 37.8 0.49
sp|Q8I0F4|LIS1_DICDI Lissencephaly-1 homolog OS=Dictyostelium dis... 37.4 0.51
sp|Q6ZQA0|NBEL2_MOUSE Neurobeachin-like protein 2 OS=Mus musculus... 38.1 0.51
sp|Q8VE80|THOC3_MOUSE THO complex subunit 3 OS=Mus musculus OX=10... 37.4 0.52
sp|Q96J01|THOC3_HUMAN THO complex subunit 3 OS=Homo sapiens OX=96... 37.4 0.52
sp|Q29RH4|THOC3_BOVIN THO complex subunit 3 OS=Bos taurus OX=9913... 37.4 0.52
sp|Q5RFQ3|PWP2_PONAB Periodic tryptophan protein 2 homolog OS=Pon... 37.8 0.53
sp|Q15269|PWP2_HUMAN Periodic tryptophan protein 2 homolog OS=Hom... 37.8 0.53
sp|Q9PTR5|LIS1_CHICK Lissencephaly-1 homolog OS=Gallus gallus OX=... 37.4 0.54
sp|Q8N4F7|RN175_HUMAN RING finger protein 175 OS=Homo sapiens OX=... 37.4 0.54
sp|C5FP68|SCONB_ARTOC Probable E3 ubiquitin ligase complex SCF su... 37.8 0.55
sp|A9BE38|MQO_PROM4 Probable malate:quinone oxidoreductase OS=Pro... 37.4 0.57
sp|Q91WQ5|TAF5L_MOUSE TAF5-like RNA polymerase II p300/CBP-associ... 37.8 0.57
sp|A3LNW3|SEC13_PICST Protein transport protein SEC13 OS=Scheffer... 37.0 0.58
sp|B5X3Z6|LIS1A_SALSA Lissencephaly-1 homolog A OS=Salmo salar OX... 37.4 0.60
sp|Q9LY41|ATL4_ARATH E3 ubiquitin-protein ligase ATL4 OS=Arabidop... 37.0 0.60
sp|Q09715|TUP11_SCHPO Transcriptional repressor tup11 OS=Schizosa... 37.4 0.60
sp|Q5IS43|LIS1_PANTR Platelet-activating factor acetylhydrolase I... 37.4 0.62
sp|P43034|LIS1_HUMAN Platelet-activating factor acetylhydrolase I... 37.4 0.62
sp|O22785|PR19B_ARATH Pre-mRNA-processing factor 19 homolog 2 OS=... 37.4 0.62
sp|Q54SF9|MHCKD_DICDI Myosin heavy chain kinase D OS=Dictyosteliu... 37.8 0.62
sp|Q9XWH0|BUB3_CAEEL Mitotic checkpoint protein bub-3 OS=Caenorha... 37.0 0.62
sp|O14301|YE85_SCHPO Uncharacterized WD repeat-containing protein... 37.4 0.63
sp|P63004|LIS1_RAT Platelet-activating factor acetylhydrolase IB ... 37.4 0.63
sp|P63005|LIS1_MOUSE Platelet-activating factor acetylhydrolase I... 37.4 0.63
sp|B0LSW3|LIS1_FELCA Platelet-activating factor acetylhydrolase I... 37.4 0.63
sp|Q9BQ87|TBL1Y_HUMAN F-box-like/WD repeat-containing protein TBL... 37.4 0.63
sp|O35142|COPB2_RAT Coatomer subunit beta' OS=Rattus norvegicus O... 37.4 0.63
sp|Q94A40|COPA1_ARATH Coatomer subunit alpha-1 OS=Arabidopsis tha... 37.8 0.64
sp|Q9GL51|LIS1_PIG Platelet-activating factor acetylhydrolase IB ... 37.0 0.66
sp|P43033|LIS1_BOVIN Platelet-activating factor acetylhydrolase I... 37.0 0.66
sp|O88879|APAF_MOUSE Apoptotic protease-activating factor 1 OS=Mu... 37.4 0.67
sp|Q2UG43|SEC13_ASPOR Protein transport protein sec13 OS=Aspergil... 37.0 0.67
sp|Q5RKI0|WDR1_RAT WD repeat-containing protein 1 OS=Rattus norve... 37.4 0.69
sp|C5DJV1|RTC1_LACTC Restriction of telomere capping protein 1 OS... 37.4 0.69
sp|Q08109|HRD1_YEAST ERAD-associated E3 ubiquitin-protein ligase ... 37.4 0.70
sp|C4YN69|RTC1_CANAW Restriction of telomere capping protein 1 OS... 37.4 0.70
sp|Q5ACL4|RTC1_CANAL Restriction of telomere capping protein 1 OS... 37.4 0.70
sp|Q8K4P0|WDR33_MOUSE pre-mRNA 3' end processing protein WDR33 OS... 37.4 0.71
sp|Q9C0J8|WDR33_HUMAN pre-mRNA 3' end processing protein WDR33 OS... 37.4 0.71
sp|O76734|TUP1_DICDI General transcriptional corepressor tupA OS=... 37.4 0.72
sp|D4D8P3|SCONB_TRIVH Probable E3 ubiquitin ligase complex SCF su... 37.4 0.73
sp|D4AM37|SCONB_ARTBC Probable E3 ubiquitin ligase complex SCF su... 37.4 0.73
sp|Q5ZME8|SMU1_CHICK WD40 repeat-containing protein SMU1 OS=Gallu... 37.0 0.74
sp|O88491|NSD1_MOUSE Histone-lysine N-methyltransferase, H3 lysin... 37.4 0.79
sp|Q7ZVF0|POC1A_DANRE POC1 centriolar protein homolog A OS=Danio ... 37.0 0.80
sp|A1CUD6|LIS11_ASPCL Nuclear distribution protein nudF 1 OS=Aspe... 37.0 0.80
sp|P87314|HIR1_SCHPO Protein hir1 OS=Schizosaccharomyces pombe (s... 37.4 0.80
sp|Q4V7Z1|POC1B_XENLA POC1 centriolar protein homolog B OS=Xenopu... 37.0 0.81
sp|Q177G4|HPS5_AEDAE BLOC-2 complex member HPS5 homolog OS=Aedes ... 37.0 0.82
sp|Q91XF4|RN167_MOUSE E3 ubiquitin-protein ligase RNF167 OS=Mus m... 36.6 0.86
sp|Q5B563|SEC13_EMENI Protein transport protein sec13 OS=Emericel... 36.6 0.89
sp|Q54J37|STRN_DICDI Striatin homolog OS=Dictyostelium discoideum... 37.0 0.89
sp|Q6CEI9|HSV2_YARLI SVP1-like protein 2 OS=Yarrowia lipolytica (... 36.6 0.90
sp|O74845|HIF2_SCHPO Set3 complex subunit hif2 OS=Schizosaccharom... 36.6 0.99
sp|Q8HXX0|LIS1_MACFA Platelet-activating factor acetylhydrolase I... 36.6 0.99
sp|Q9LTA6|WAV3_ARATH E3 ubiquitin-protein ligase WAV3 OS=Arabidop... 37.0 0.99
sp|Q6ZPG2|WDR90_MOUSE WD repeat-containing protein 90 OS=Mus musc... 37.0 1.00
sp|C5JD40|LIS1_BLAGS Nuclear distribution protein PAC1 OS=Blastom... 36.6 1.0
sp|C5GVJ9|LIS1_AJEDR Nuclear distribution protein PAC1 OS=Ajellom... 36.6 1.0
sp|Q9LV27|LST81_ARATH Target of rapamycin complex subunit LST8-1 ... 36.2 1.0
sp|P53196|RPN14_YEAST 26S proteasome regulatory subunit RPN14 OS=... 36.6 1.0
sp|P0CS42|LIS1_CRYNJ Nuclear distribution protein PAC1 OS=Cryptoc... 36.6 1.1
sp|P0CS43|LIS1_CRYNB Nuclear distribution protein PAC1 OS=Cryptoc... 36.6 1.1
sp|Q23256|WDR53_CAEEL WD repeat-containing protein wdr-5.3 OS=Cae... 36.6 1.1
sp|Q6R2V0|WNK1_PIG Serine/threonine-protein kinase WNK1 OS=Sus sc... 37.0 1.1
sp|Q5XIL0|RN167_RAT E3 ubiquitin-protein ligase RNF167 OS=Rattus ... 36.2 1.1
sp|B5X3C4|LIS1B_SALSA Lissencephaly-1 homolog B OS=Salmo salar OX... 36.6 1.1
sp|Q852U6|RHY1A_ARATH Probable E3 ubiquitin-protein ligase RHY1A ... 35.8 1.1
sp|P41811|COPB2_YEAST Coatomer subunit beta' OS=Saccharomyces cer... 36.6 1.1
sp|A5DHD9|SEC13_PICGU Protein transport protein SEC13 OS=Meyerozy... 36.2 1.2
sp|Q803D2|LIS1B_DANRE Lissencephaly-1 homolog B OS=Danio rerio OX... 36.2 1.2
sp|Q8NEG5|ZSWM2_HUMAN E3 ubiquitin-protein ligase ZSWIM2 OS=Homo ... 36.6 1.2
sp|Q9H4A3|WNK1_HUMAN Serine/threonine-protein kinase WNK1 OS=Homo... 37.0 1.2
sp|A8JAN3|POC16_CHLRE Centriole proteome protein 16 OS=Chlamydomo... 37.0 1.2
sp|Q54U63|LVSC_DICDI BEACH domain-containing protein lvsC OS=Dict... 37.0 1.2
sp|A3LQI7|LKA42_PICST Leucine aminopeptidase 2-2 OS=Scheffersomyc... 36.6 1.2
sp|Q0WQX9|WAVH2_ARATH Probable E3 ubiquitin-protein ligase WAVH2 ... 36.6 1.2
sp|A8ILK1|CFA52_CHLRE Cilia- and flagella-associated protein 52 O... 36.6 1.2
sp|Q9NB71|HIW_DROME E3 ubiquitin-protein ligase highwire OS=Droso... 36.6 1.2
sp|Q6DIF4|WDR1_XENTR WD repeat-containing protein 1 OS=Xenopus tr... 36.6 1.3
sp|P41318|LST8_YEAST Target of rapamycin complex subunit LST8 OS=... 35.8 1.3
sp|O96028|NSD2_HUMAN Histone-lysine N-methyltransferase NSD2 OS=H... 36.6 1.3
sp|Q4RJN5|LIS1_TETNG Lissencephaly-1 homolog OS=Tetraodon nigrovi... 36.2 1.3
sp|Q9EPV5|APAF_RAT Apoptotic protease-activating factor 1 OS=Ratt... 36.6 1.3
sp|Q6BZX5|SEC13_YARLI Protein transport protein SEC13 OS=Yarrowia... 35.8 1.4
sp|Q9FLX9|NLE1_ARATH Notchless protein homolog OS=Arabidopsis tha... 36.2 1.4
sp|Q6NVM2|KTNB1_XENTR Katanin p80 WD40 repeat-containing subunit ... 36.2 1.4
sp|Q6ZJW8|FIE1_ORYSJ Polycomb group protein FIE1 OS=Oryza sativa ... 36.2 1.4
sp|Q9USL1|THOC3_SCHPO THO complex subunit Tho3 OS=Schizosaccharom... 35.8 1.4
sp|Q0CHM0|SEC13_ASPTN Protein transport protein sec13 OS=Aspergil... 35.8 1.5
sp|Q0CQ54|HIR1_ASPTN Protein hir1 OS=Aspergillus terreus (strain ... 36.2 1.5
sp|B3MC74|CIAO1_DROAN Probable cytosolic iron-sulfur protein asse... 35.8 1.7
sp|P54686|AIP1_DICDI Actin-interacting protein 1 OS=Dictyostelium... 36.2 1.7
sp|B0X2V9|WDR48_CULQU WD repeat-containing protein 48 homolog OS=... 36.2 1.7
sp|A5DNK9|IPI3_PICGU Pre-rRNA-processing protein IPI3 OS=Meyerozy... 35.8 1.7
sp|Q8BHJ5|TBL1R_MOUSE F-box-like/WD repeat-containing protein TBL... 35.8 1.7
sp|Q9BZK7|TBL1R_HUMAN F-box-like/WD repeat-containing protein TBL... 35.8 1.7
sp|Q9H920|RN121_HUMAN E3 ubiquitin ligase RNF121 OS=Homo sapiens ... 35.8 1.8
sp|B6IST2|LEXA_RHOCS LexA repressor OS=Rhodospirillum centenum (s... 35.5 1.8
sp|Q54RP0|AGTA_DICDI UDP-galactose:fucoside alpha-3-galactosyltra... 35.8 1.8
sp|Q75CC8|HRD1_EREGS ERAD-associated E3 ubiquitin-protein ligase ... 35.8 1.9
sp|O55176|PJA1_MOUSE E3 ubiquitin-protein ligase Praja-1 OS=Mus m... 35.8 1.9
sp|G5ECZ4|DYF2_CAEEL WD repeat-containing protein dyf-2 OS=Caenor... 36.2 1.9
sp|O13046|WDHD1_XENLA WD repeat and HMG-box DNA-binding protein 1... 36.2 1.9
sp|Q4R4I8|COPB2_MACFA Coatomer subunit beta' OS=Macaca fascicular... 35.8 1.9
sp|Q9C1X4|YKW3_SCHPO Uncharacterized RING finger protein P32A8.03... 35.8 1.9
sp|Q9FF61|SM3L1_ARATH Putative SWI/SNF-related matrix-associated ... 35.8 2.0
sp|Q9QXE7|TBL1X_MOUSE F-box-like/WD repeat-containing protein TBL... 35.8 2.0
sp|B4LJT7|CIAO1_DROVI Probable cytosolic iron-sulfur protein asse... 35.5 2.0
sp|B4QFZ8|CIAO1_DROSI Probable cytosolic iron-sulfur protein asse... 35.5 2.0
sp|Q6S7B0|TAF5_ARATH Transcription initiation factor TFIID subuni... 35.8 2.0
sp|Q68FJ6|PK1IP_XENLA p21-activated protein kinase-interacting pr... 35.5 2.0
sp|P35605|COPB2_BOVIN Coatomer subunit beta' OS=Bos taurus OX=991... 35.8 2.0
sp|Q11176|WDR1_CAEEL Actin-interacting protein 1 OS=Caenorhabditi... 35.8 2.0
sp|Q5R664|COPB2_PONAB Coatomer subunit beta' OS=Pongo abelii OX=9... 35.8 2.1
sp|A2CEH0|POC1B_DANRE POC1 centriolar protein homolog B OS=Danio ... 35.8 2.1
sp|O54880|RPH3L_RAT Rab effector Noc2 OS=Rattus norvegicus OX=101... 35.5 2.1
sp|D5GBI7|LIS1_TUBMM Nuclear distribution protein PAC1 OS=Tuber m... 35.5 2.1
sp|Q5VQ78|COB21_ORYSJ Coatomer subunit beta'-1 OS=Oryza sativa su... 35.8 2.2
sp|B8P4B0|LIS11_POSPM Nuclear distribution protein PAC1-1 OS=Post... 35.5 2.2
sp|Q6PAX7|WDR1B_XENLA WD repeat-containing protein 1-B OS=Xenopus... 35.8 2.2
sp|B6QC06|LIS12_TALMQ Nuclear distribution protein nudF 2 OS=Tala... 35.5 2.3
sp|Q7K1Y4|CIAO1_DROME Probable cytosolic iron-sulfur protein asse... 35.5 2.3
sp|B6K1G6|CFD1_SCHJY Probable cytosolic Fe-S cluster assembly fac... 35.5 2.3
sp|P62884|GBLP_LEIIN Small ribosomal subunit protein RACK1 OS=Lei... 35.1 2.3
sp|P62883|GBLP_LEICH Small ribosomal subunit protein RACK1 OS=Lei... 35.1 2.3
sp|Q3UGF1|WDR19_MOUSE WD repeat-containing protein 19 OS=Mus musc... 35.8 2.3
sp|P35606|COPB2_HUMAN Coatomer subunit beta' OS=Homo sapiens OX=9... 35.8 2.3
sp|Q58D79|RPH3L_BOVIN Rab effector Noc2 OS=Bos taurus OX=9913 GN=... 35.1 2.3
sp|O55029|COPB2_MOUSE Coatomer subunit beta' OS=Mus musculus OX=1... 35.8 2.4
sp|B4HRQ6|CIAO1_DROSE Probable cytosolic iron-sulfur protein asse... 35.1 2.4
sp|Q8NG27|PJA1_HUMAN E3 ubiquitin-protein ligase Praja-1 OS=Homo ... 35.5 2.4
sp|Q4PHV3|IPI3_MYCMD Pre-rRNA-processing protein IPI3 OS=Mycosarc... 35.5 2.5
sp|B4KTK4|CIAO1_DROMO Probable cytosolic iron-sulfur protein asse... 35.1 2.6
sp|P78750|UTP18_SCHPO Probable U3 small nucleolar RNA-associated ... 35.5 2.6
sp|A2QHM1|SEC13_ASPNC Protein transport protein sec13 OS=Aspergil... 35.1 2.6
sp|A1DP19|LIS1_NEOFI Nuclear distribution protein nudF OS=Neosart... 35.5 2.6
sp|Q9SUS4|RHA1A_ARATH Probable E3 ubiquitin-protein ligase RHA1A ... 33.9 2.6
sp|Q4WLM7|LIS1_ASPFU Nuclear distribution protein nudF OS=Aspergi... 35.5 2.7
sp|B0XM00|LIS1_ASPFC Nuclear distribution protein nudF OS=Aspergi... 35.5 2.7
sp|Q8R1Z9|RN121_MOUSE E3 ubiquitin ligase Rnf121 OS=Mus musculus ... 35.1 2.7
sp|Q06078|UTP21_YEAST U3 small nucleolar RNA-associated protein 2... 35.5 2.7
sp|Q13702|RAPSN_HUMAN 43 kDa receptor-associated protein of the s... 35.1 2.8
sp|Q5AEF2|SEC13_CANAL Protein transport protein SEC13 OS=Candida ... 35.1 2.9
sp|P36130|CAF4_YEAST CCR4-associated factor 4 OS=Saccharomyces ce... 35.5 2.9
sp|Q16MY0|WDR48_AEDAE WD repeat-containing protein 48 homolog OS=... 35.5 3.0
sp|Q28I85|POC1A_XENTR POC1 centriolar protein homolog A OS=Xenopu... 35.1 3.0
sp|A5E6M3|RTC1_LODEL Restriction of telomere capping protein 1 OS... 35.5 3.1
sp|Q6P360|RN121_XENTR E3 ubiquitin ligase Rnf121 OS=Xenopus tropi... 35.1 3.1
sp|Q6DD32|RN121_XENLA E3 ubiquitin ligase Rnf121 OS=Xenopus laevi... 35.1 3.1
sp|A6ZZZ8|CAF4_YEAS7 CCR4-associated factor 4 OS=Saccharomyces ce... 35.1 3.1
sp|Q5REG7|LIS1_PONAB Platelet-activating factor acetylhydrolase I... 35.1 3.1
sp|Q9LT47|FIE_ARATH Polycomb group protein FERTILIZATION-INDEPEND... 35.1 3.1
sp|Q01277|SCONB_NEUCR Probable E3 ubiquitin ligase complex SCF su... 35.1 3.2
sp|Q96L73|NSD1_HUMAN Histone-lysine N-methyltransferase, H3 lysin... 35.5 3.2
sp|F4IDY5|BTSL1_ARATH Zinc finger protein BRUTUS-like At1g18910 O... 35.5 3.3
sp|Q8W1K8|MUT11_CHLRE Protein Mut11 OS=Chlamydomonas reinhardtii ... 34.7 3.5
sp|F4IH25|BOP1_ARATH Ribosome biogenesis protein BOP1 homolog OS=... 35.1 3.6
sp|P12672|RAPSN_MOUSE 43 kDa receptor-associated protein of the s... 34.7 3.6
sp|A5DXE2|SEC13_LODEL Protein transport protein SEC13 OS=Lodderom... 34.7 3.7
sp|Q2KIG2|WDR5_BOVIN WD repeat-containing protein 5 OS=Bos taurus... 34.7 3.9
sp|Q5BLX8|WDR83_RAT WD repeat domain-containing protein 83 OS=Rat... 34.7 4.0
sp|Q9DAJ4|WDR83_MOUSE WD repeat domain-containing protein 83 OS=M... 34.7 4.0
sp|Q9LYK6|APRF1_ARATH Protein ANTHESIS POMOTING FACTOR 1 OS=Arabi... 34.7 4.0
sp|B8M0Q1|LIS1_TALSN Nuclear distribution protein nudF OS=Talarom... 34.7 4.1
sp|Q96KV7|WDR90_HUMAN WD repeat-containing protein 90 OS=Homo sap... 35.1 4.1
sp|Q9GL21|UACA_CANLF Uveal autoantigen with coiled-coil domains a... 35.1 4.1
sp|Q498M4|WDR5_RAT WD repeat-containing protein 5 OS=Rattus norve... 34.3 4.1
sp|P61965|WDR5_MOUSE WD repeat-containing protein 5 OS=Mus muscul... 34.3 4.1
sp|P61964|WDR5_HUMAN WD repeat-containing protein 5 OS=Homo sapie... 34.3 4.1
sp|Q9V3J8|WDS_DROME Protein will die slowly OS=Drosophila melanog... 34.7 4.2
sp|B8PD53|LIS12_POSPM Nuclear distribution protein PAC1-2 OS=Post... 34.7 4.2
sp|Q6H8D6|COB23_ORYSJ Putative coatomer subunit beta'-3 OS=Oryza ... 34.7 4.3
sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens... 35.1 4.4
sp|Q62191|RO52_MOUSE E3 ubiquitin-protein ligase TRIM21 OS=Mus mu... 34.7 4.4
sp|Q9CAA0|COB21_ARATH Coatomer subunit beta'-1 OS=Arabidopsis tha... 34.7 4.4
sp|Q5F201|CFA52_MOUSE Cilia- and flagella-associated protein 52 O... 34.7 4.5
sp|Q6CN23|HSV2_KLULA SVP1-like protein 2 OS=Kluyveromyces lactis ... 34.3 4.6
sp|B8D8T3|QUEA_BUCA5 S-adenosylmethionine:tRNA ribosyltransferase... 34.3 4.6
sp|A2QP30|LIS1_ASPNC Nuclear distribution protein nudF OS=Aspergi... 34.3 4.7
sp|Q5M786|WDR5_XENTR WD repeat-containing protein 5 OS=Xenopus tr... 34.3 4.7
sp|B8D737|QUEA_BUCAT S-adenosylmethionine:tRNA ribosyltransferase... 34.3 4.8
sp|P57232|QUEA_BUCAI S-adenosylmethionine:tRNA ribosyltransferase... 34.3 4.8
sp|C4JPW9|LIS12_UNCRE Nuclear distribution protein PAC1-2 OS=Unci... 34.3 4.9
sp|C0S902|LIS1_PARBP Nuclear distribution protein PAC1 OS=Paracoc... 34.3 4.9
sp|C1GB49|LIS1_PARBD Nuclear distribution protein PAC1 OS=Paracoc... 34.3 4.9
sp|Q8YTC2|Y2800_NOSS1 Uncharacterized WD repeat-containing protei... 34.7 5.0
sp|Q8VZM1|NAA15_ARATH N-terminal acetyltransferase A complex auxi... 34.7 5.1
sp|Q9I9H8|APAF_DANRE Apoptotic protease-activating factor 1 OS=Da... 34.7 5.1
sp|P87119|MU145_SCHPO RING finger protein mug145 OS=Schizosacchar... 34.3 5.2
sp|Q6DFB8|TTC37_XENLA Tetratricopeptide repeat protein 37 OS=Xeno... 34.7 5.3
sp|Q09485|RAPSN_CAEEL 43 kDa receptor-associated protein of the s... 34.3 5.3
sp|B6HP56|LIS11_PENRW Nuclear distribution protein nudF 1 OS=Peni... 34.3 5.4
sp|A8ID74|BOP1_CHLRE Ribosome biogenesis protein BOP1 homolog OS=... 34.3 5.5
sp|Q0BTY8|LEXA_GRABC LexA repressor OS=Granulibacter bethesdensis... 33.9 5.7
sp|Q0USG2|CIAO1_PHANO Probable cytosolic iron-sulfur protein asse... 34.3 5.9
sp|F1LTR1|WDR26_RAT WD repeat-containing protein 26 OS=Rattus nor... 33.9 7.1
sp|Q8C6G8|WDR26_MOUSE WD repeat-containing protein 26 OS=Mus musc... 33.9 7.3
sp|P53804|TTC3_HUMAN E3 ubiquitin-protein ligase TTC3 OS=Homo sap... 33.9 9.1
sp|P25635|PWP2_YEAST Periodic tryptophan protein 2 OS=Saccharomyc... 33.9 9.4
>sp|P49754|VPS41_HUMAN Vacuolar protein sorting-associated protein
41 homolog OS=Homo sapiens OX=9606 GN=VPS41 PE=1 SV=3
Length=854
Score = 1220 bits (3156), Expect = 0.0, Method: Composition-based stats.
Identities = 854/854 (100%), Positives = 854/854 (100%), Gaps = 0/854 (0%)
Query 1 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL 60
MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL
Sbjct 1 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL 60
Query 61 GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH 120
GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH
Sbjct 61 GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH 120
Query 121 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR 180
ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR
Sbjct 121 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR 180
Query 181 GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV 240
GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV
Sbjct 181 GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV 240
Query 241 CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA 300
CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA
Sbjct 241 CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA 300
Query 301 RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER 360
RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER
Sbjct 301 RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER 360
Query 361 DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK 420
DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK
Sbjct 361 DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK 420
Query 421 ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI 480
ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI
Sbjct 421 ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI 480
Query 481 REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF 540
REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF
Sbjct 481 REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF 540
Query 541 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK 600
QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK
Sbjct 541 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK 600
Query 601 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL 660
LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL
Sbjct 601 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL 660
Query 661 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH 720
SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH
Sbjct 661 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH 720
Query 721 VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM 780
VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM
Sbjct 721 VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM 780
Query 781 KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA 840
KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA
Sbjct 781 KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA 840
Query 841 KNRGPGSAILEMKK 854
KNRGPGSAILEMKK
Sbjct 841 KNRGPGSAILEMKK 854
>sp|Q5KU39|VPS41_MOUSE Vacuolar protein sorting-associated protein
41 homolog OS=Mus musculus OX=10090 GN=Vps41 PE=1 SV=1
Length=853
Score = 1207 bits (3123), Expect = 0.0, Method: Composition-based stats.
Identities = 805/827 (97%), Positives = 823/827 (99%), Gaps = 0/827 (0%)
Query 28 PKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKI 87
PKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKI
Sbjct 27 PKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKI 86
Query 88 NQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTG 147
NQISLD+SGEHMGVCSEDGK+QVFGLYSGEEFHETFDCPIKIIAVHP FVRSSCKQFVTG
Sbjct 87 NQISLDDSGEHMGVCSEDGKLQVFGLYSGEEFHETFDCPIKIIAVHPQFVRSSCKQFVTG 146
Query 148 GKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITNVP 207
GKKLLLFER+WMNRWKS+VLHEGEGNIRSVKWRGHLIAWANNMGVK+FDI SKQRI+NVP
Sbjct 147 GKKLLLFERTWMNRWKSSVLHEGEGNIRSVKWRGHLIAWANNMGVKVFDITSKQRISNVP 206
Query 208 RDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFET 267
RDDISLRPDMYPCSLCWKDNVTLIIGWGTS+K+CSVKERHASEMRDLPSRYVEIVSQFET
Sbjct 207 RDDISLRPDMYPCSLCWKDNVTLIIGWGTSIKICSVKERHASEMRDLPSRYVEIVSQFET 266
Query 268 EFYISGLAPLCDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSETCEEISSDALTVRGF 327
EFYISGLAPLCDQLVVLSYVKE+SEKTEREYCARPRLDIIQPL ETCEEISSDALTVRGF
Sbjct 267 EFYISGLAPLCDQLVVLSYVKEVSEKTEREYCARPRLDIIQPLPETCEEISSDALTVRGF 326
Query 328 QENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQK 387
QENECRDYHLEYSEGESLFY+VSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQ+
Sbjct 327 QENECRDYHLEYSEGESLFYVVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQR 386
Query 388 NIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISP 447
NIKRHKILDIGLAY+NHLVERG+YD+AARKCQKILGKNA+LWEYEVYKFKEIGQLKAISP
Sbjct 387 NIKRHKILDIGLAYVNHLVERGEYDMAARKCQKILGKNASLWEYEVYKFKEIGQLKAISP 446
Query 448 YLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQN 507
YLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQN
Sbjct 447 YLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQN 506
Query 508 KTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKA 567
KTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKA
Sbjct 507 KTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKA 566
Query 568 VDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPN 627
VDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPN
Sbjct 567 VDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPN 626
Query 628 LLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFA 687
LLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFA
Sbjct 627 LLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFA 686
Query 688 KEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKIL 747
KEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKIL
Sbjct 687 KEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKIL 746
Query 748 QDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPF 807
QDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILP+DAAKPF
Sbjct 747 QDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPTDAAKPF 806
Query 808 SVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGPGSAILEMKK 854
SVVVFHCRHMFHKECLPMPSMN+ AQ+CNICSAKNRGPGSAILEMKK
Sbjct 807 SVVVFHCRHMFHKECLPMPSMNAPAQYCNICSAKNRGPGSAILEMKK 853
>sp|E7F590|VPS41_DANRE Vacuolar protein sorting-associated protein
41 homolog OS=Danio rerio OX=7955 GN=vps41 PE=1 SV=1
Length=854
Score = 1185 bits (3066), Expect = 0.0, Method: Composition-based stats.
Identities = 702/854 (82%), Positives = 768/854 (90%), Gaps = 0/854 (0%)
Query 1 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLAL 60
MAE EEQ EESTDESEEE++EEEPKLKYERL+NGVTEILQKDAASCMTVHDKFLAL
Sbjct 1 MAEVEEQGRKLSEESTDESEEEDTEEEPKLKYERLTNGVTEILQKDAASCMTVHDKFLAL 60
Query 61 GTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH 120
GTH+GKV+LLD+QGN+TQKF++S VKINQISLDESG+H+G+CSEDGKVQVFGLY+ E FH
Sbjct 61 GTHFGKVFLLDIQGNVTQKFEISSVKINQISLDESGDHVGICSEDGKVQVFGLYTREGFH 120
Query 121 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR 180
E FDCPIK++A+HP F +S+ KQFVTGG KLLL+ER+W+NRWK++VLHEGEGNI SVKWR
Sbjct 121 ENFDCPIKVVALHPQFSKSNNKQFVTGGNKLLLYERNWLNRWKTSVLHEGEGNITSVKWR 180
Query 181 GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKV 240
G+LIAWANN+GVKI+DI SKQRITNV RD+ SLRPDMYPCSLCWKDN TLIIGWG SVK+
Sbjct 181 GNLIAWANNVGVKIYDIGSKQRITNVLRDNTSLRPDMYPCSLCWKDNTTLIIGWGCSVKI 240
Query 241 CSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCA 300
C+VKER +EMRDLPSRYVEIVS FETEF+ISGLAPL DQLV L YVKE S+ E E+
Sbjct 241 CAVKERDPTEMRDLPSRYVEIVSAFETEFFISGLAPLADQLVTLYYVKENSDHMEEEFRT 300
Query 301 RPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKER 360
RPRLDIIQPL E CEEISSDALTVR FQEN+CRDY LE+SEGESLFYI+SP+D+VVAKER
Sbjct 301 RPRLDIIQPLPEGCEEISSDALTVRNFQENQCRDYRLEHSEGESLFYIISPKDIVVAKER 360
Query 361 DQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQK 420
DQDDHIDWLLEKKKYEEALMAAEIS KNIKRH + IG+AYINHLVE+GDYD AARKCQK
Sbjct 361 DQDDHIDWLLEKKKYEEALMAAEISFKNIKRHDVQKIGMAYINHLVEKGDYDTAARKCQK 420
Query 421 ILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLI 480
+LGKN LWE EVY+FK IGQLKAIS YLPRGD L+P IYEMILH+FL++DYEGFATLI
Sbjct 421 VLGKNMDLWENEVYRFKTIGQLKAISQYLPRGDLRLRPAIYEMILHDFLKTDYEGFATLI 480
Query 481 REWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF 540
REWPG+LYNN IVQAV +HLKKD N LL TLAELYTYD+ Y ALEIYL LRHKDV+
Sbjct 481 REWPGELYNNMAIVQAVNEHLKKDPTNSILLTTLAELYTYDQRYDRALEIYLRLRHKDVY 540
Query 541 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHK 600
QLIHKHNLFSSIKDKIVLLMDFD EKAVDMLLDNEDKIS+ KVVEEL+DRPEL HVYLHK
Sbjct 541 QLIHKHNLFSSIKDKIVLLMDFDKEKAVDMLLDNEDKISMDKVVEELKDRPELLHVYLHK 600
Query 601 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLL 660
LFKRDHHKGQ+YHE+QISLYAE+DRPNLLPFLR+S HCPLEKALEICQQR+FVEETV+LL
Sbjct 601 LFKRDHHKGQKYHERQISLYAEFDRPNLLPFLRESMHCPLEKALEICQQRHFVEETVFLL 660
Query 661 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTH 720
SRMGN R AL+MIMEEL +VDKAIEFAKEQDD ELWEDLI YSIDKPPFITGLLNNIGTH
Sbjct 661 SRMGNCRRALQMIMEELANVDKAIEFAKEQDDRELWEDLISYSIDKPPFITGLLNNIGTH 720
Query 721 VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQM 780
VDPILLIHRIKEGMEIPNLRDSLVKIL DYNLQILLREGCKKILVADSLSLL++MHRTQ
Sbjct 721 VDPILLIHRIKEGMEIPNLRDSLVKILHDYNLQILLREGCKKILVADSLSLLQRMHRTQK 780
Query 781 KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA 840
KGV VDEENICESC +PILPSD A+ F VVVFHCRHMFHKECLP P Q+CNICSA
Sbjct 781 KGVRVDEENICESCHTPILPSDTAQAFGVVVFHCRHMFHKECLPSPGSIPGIQYCNICSA 840
Query 841 KNRGPGSAILEMKK 854
K RGPGS ILEMKK
Sbjct 841 KRRGPGSGILEMKK 854
>sp|P93231|VPS41_SOLLC Vacuolar protein sorting-associated protein
41 homolog OS=Solanum lycopersicum OX=4081 GN=VPS41 PE=2
SV=1
Length=960
Score = 977 bits (2526), Expect = 0.0, Method: Composition-based stats.
Identities = 300/871 (34%), Positives = 474/871 (54%), Gaps = 85/871 (10%)
Query 28 PKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKI 87
P+LKY+R+ V +L DAA+C+ V ++ +ALGTH G V++LD GN ++F +
Sbjct 36 PRLKYQRMGASVPSLLSADAATCIAVAERMIALGTHGGAVHILDFLGNQVKEFAAHTAAV 95
Query 88 NQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTG 147
N + D GE++G CS+DG V + L++ E + P+K IA+ P + R+S ++FVTG
Sbjct 96 NDLCFDTDGEYVGSCSDDGSVVINSLFTDERMKFEYHRPMKAIALDPDYARTSSRRFVTG 155
Query 148 G--KKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITN 205
G +L L + W+ ++ VLH GEG I +VKWR L+AWAN+ GVK++D + QRIT
Sbjct 156 GLAGQLYLNVKKWLG-YRDQVLHSGEGPIHAVKWRTSLVAWANDTGVKVYDASNDQRITF 214
Query 206 VPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHAS-------EMRDLPSRY 258
+ R RP++ + W+D+ L+IGWGTSVK+ ++ + M
Sbjct 215 IERPRGIPRPELLLPHIVWQDDSLLVIGWGTSVKIALIRTTQSKGANGTYKHMSMSSLNQ 274
Query 259 VEIVSQFETEFYISGLAPLCDQLVVLSYVKEISE---------KTEREYCARPRLDIIQP 309
V+IV+ F+T ++ISG+AP D LV+L+Y+ + + + RP + ++
Sbjct 275 VDIVASFQTSYFISGIAPFGDSLVILAYIPGEEDGEKDFSSTIPSRQGNAQRPEVRVV-- 332
Query 310 LSETCEEISSDALTVRGFQENECRDYHLEYS--------------EGESLFYIVSPRDVV 355
+ +E+++DAL V GF+ + +DY L ++ E L+YIVSP+DVV
Sbjct 333 -TWNNDELATDALPVHGFEHYKAKDYSLAHAPFSGSSYAGGQWAAGDEPLYYIVSPKDVV 391
Query 356 VAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAA 415
+AK RD +DHI+WLL+ +E+AL A E +Q + + ++G Y++HL+ Y AA
Sbjct 392 IAKPRDAEDHINWLLQHGWHEKALEAVEANQG--QSELLDEVGSRYLDHLIVERKYAEAA 449
Query 416 RKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLES--DY 473
C K+L +A+ WE V+ F + QL + PY+P +P L+ YE+ L + +
Sbjct 450 SLCPKLLRGSASAWERWVFHFAHLRQLPVLVPYIPTENPRLRDTAYEVALVALATNPSFH 509
Query 474 EGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLT 533
+ + ++ WP +Y+ + + A+ + S L + LAELY D + A +Y
Sbjct 510 KDLLSTVKSWPPRIYSTTPVFSAIEPQINTSSMTDPLKEALAELYVIDGQHDKAFALYAD 569
Query 534 LRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELE----- 588
L D+F I KHNL ++++K++ LM D ++AV +L+ D I +VV +L
Sbjct 570 LMKPDLFDFIEKHNLHDAVREKVLQLMMIDCKRAVLLLIQQRDLIPPSEVVSQLIAARDK 629
Query 589 -DRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEIC 647
D H+YLH LF+ + H G+ YH+ Q+ LYA+YD LL FLR S H LEKA EIC
Sbjct 630 CDYRYFLHLYLHSLFEVNLHAGKDYHDMQVELYADYDPKMLLTFLRSSQHYTLEKAYEIC 689
Query 648 QQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKP 707
+++ ++E V++L RMGN++ AL +I+ L D+++AIEF Q D ELWE+LI S KP
Sbjct 690 VKKDLLKEQVFILGRMGNAKQALAVIINRLGDIEEAIEFVSMQQDDELWEELIQQSFHKP 749
Query 708 PFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVAD 767
+ LL + ++DP+ +++ + +EIP LRD LVKI+ DY + LR GC IL AD
Sbjct 750 EMVGVLLEHTVGNLDPLYIVNMLPNDLEIPRLRDRLVKIVTDYRTETSLRHGCNDILKAD 809
Query 768 SLSLLKKMHRTQMKGVLVDEE-----------------------------------NICE 792
++LL K ++ +GV + +E C
Sbjct 810 CVNLLVKYYKEAKRGVCLSDEVDDVSSRRGEKSVSHLGERTMSLKSVEVKSKTRGGGRCC 869
Query 793 SCLSPILPSDAAKPFSVVVFHCRHMFHKECL 823
C P + S++ F C H +H CL
Sbjct 870 ICFDPF----SILNVSIIAFFCCHAYHTTCL 896
>sp|P93043|VPS41_ARATH Vacuolar protein sorting-associated protein
41 homolog OS=Arabidopsis thaliana OX=3702 GN=VPS41 PE=1
SV=3
Length=980
Score = 958 bits (2475), Expect = 0.0, Method: Composition-based stats.
Identities = 310/886 (35%), Positives = 478/886 (54%), Gaps = 101/886 (11%)
Query 28 PKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKI 87
P+LKY+R+ V +L DAASC+ V + +ALGTH G V +LD+ GN ++F +
Sbjct 42 PRLKYQRMGGNVPALLSNDAASCIAVAARMIALGTHDGTVRILDLLGNQVKEFRAHTAPV 101
Query 88 NQISLDESGEHMGVCSEDGKVQVFGLYSGEE-FHETFDCPIKIIAVHPHFVRSSCKQFVT 146
N I+ D GE++G CS+DG V + L++ +E + P+K I++ P + + K+FV
Sbjct 102 NDINFDTEGEYIGSCSDDGSVVINSLFTDDEKMKFDYHRPMKAISLDPDYTKKQSKRFVA 161
Query 147 GG--KKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRIT 204
GG L + + W K VLH GEG I SVKWRG LIAWAN++GVK++D QR+T
Sbjct 162 GGLAGHLYMNSKKWFGN-KDQVLHSGEGPIHSVKWRGSLIAWANDVGVKVYDTAKDQRVT 220
Query 205 NVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVK--ERHASEMRDLPSR---YV 259
+ + S RP+ L W+D+ L+IGWGTSVK+ S+K ++ R + V
Sbjct 221 FIEKPRGSPRPEALLPHLVWQDDTLLVIGWGTSVKIASIKSDQQQTGTFRQIQMSSLTQV 280
Query 260 EIVSQFETEFYISGLAPLCDQLVVLSYVK----------EISEKTEREYCARPRLDIIQP 309
+IV+ F+T +YISG+AP D LV+L+Y+ + + + RP + I+
Sbjct 281 DIVASFQTSYYISGIAPFGDSLVILAYIPIEGDGEKEFSSTTTLSRQGNAQRPEIRIV-- 338
Query 310 LSETCEEISSDALTVRGFQENECRDYHLEYS--------------EGESLFYIVSPRDVV 355
S +E++ DAL V GF+ + +DY L ++ E L+YIVSP+DVV
Sbjct 339 -SWNNDELTMDALPVHGFEHYKAKDYSLAHAPFPGSSYAGGQWAAGDEPLYYIVSPKDVV 397
Query 356 VAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILD-IGLAYINHLVERGDYDIA 414
+AK RD +DHI+WLL+ +E+AL A E S+ R +++D +G Y++HL+ Y A
Sbjct 398 IAKPRDAEDHINWLLQHGFHEKALAAVEASE---GRTELIDKVGAGYLDHLIVERKYAEA 454
Query 415 ARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLES--D 472
A C K+L +A+ WE V+ F ++ QL + PY+P +P LK +YE+ L +
Sbjct 455 ASLCPKLLRGSASAWERWVFHFAQLRQLPVLVPYMPTDNPRLKDTVYEVALVALATNPSY 514
Query 473 YEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYL 532
++ + ++ WP +Y+ ++ A+ L S L + LAELY D Y A +Y
Sbjct 515 HKELLSAVKSWPRSVYSALTVISAIEPQLNTSSMTDALKEALAELYVIDGQYQKAFSLYA 574
Query 533 TLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEEL---ED 589
L +VF I K++L +I+ K+V LM D ++A + + N D I +VV +L
Sbjct 575 DLLKPEVFDFIEKYSLHEAIRGKVVQLMLLDCKRATVLFIQNRDLIPPSEVVPQLLKAGK 634
Query 590 RPELQHV------------YLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTH 637
P++ YLH LF+ H G+ +H+ Q+ LYAEYD LLPFLR S H
Sbjct 635 NPQVLKAGKKCDSRYYLYLYLHALFEVSHDTGKDFHDMQVELYAEYDTKMLLPFLRSSQH 694
Query 638 CPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWE 697
LEKA E+C +++F+ E V++L RMGN++ AL +I+ +L D+++A+EF Q D +LWE
Sbjct 695 YKLEKAYELCVKKDFLREQVFVLGRMGNAKQALAVIINKLGDIEEAVEFVSMQHDDDLWE 754
Query 698 DLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLR 757
+LI ++KP + LL + ++DP+ +++ + G+EIP LRD LVKI+ DY + LR
Sbjct 755 ELIKQCLNKPEMVGLLLEHTVGNLDPLYIVNMVPNGLEIPRLRDRLVKIVTDYRTETSLR 814
Query 758 EGCKKILVADSLSLLKKMHRTQMKGVLVDEEN---------------------------- 789
GC IL D ++LL K +GV + E+
Sbjct 815 HGCNDILKTDIVNLLVKCFNEARRGVCLSHEDDDSRAKREDNNRSSFSQRMVVDKSLSIK 874
Query 790 ------------ICESCLSPILPSDAAKPFSVVVFHCRHMFHKECL 823
C C P+ + + +VVVF C H +H+ CL
Sbjct 875 MTEVKSKTRGDTRCCMCFDPV----SIRGDTVVVFFCCHAYHETCL 916
>sp|Q7PL76|VPS41_DROME Vacuolar protein sorting-associated protein
41 homolog OS=Drosophila melanogaster OX=7227 GN=lt PE=1
SV=2
Length=841
Score = 920 bits (2377), Expect = 0.0, Method: Composition-based stats.
Identities = 316/835 (38%), Positives = 487/835 (58%), Gaps = 36/835 (4%)
Query 22 EESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGN-ITQKF 80
E + EPK KY RL+N + +L D +C VH KFL GT G+V + D QGN +
Sbjct 18 NEEDVEPKFKYHRLANDLKYMLNADVITCSAVHLKFLIFGTFRGRVCIFDHQGNSVYSNL 77
Query 81 DV-----SPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE-TFDCPIKIIAVHP 134
V +N I +D GE++ CS+DGKV + GL+S + H +F IK++++ P
Sbjct 78 SASERHTHQVAVNNIDVDHKGEYVATCSDDGKVNITGLFSSDNNHSLSFGKFIKVVSLEP 137
Query 135 HFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKI 194
++ K+FV G KL+L+ER+ + + K L EG++ S+ W G+ IAWA+++GV++
Sbjct 138 D-SKAHIKRFVVGDDKLILYERNLLKKLKPVELCSVEGSVLSICWHGNFIAWASHIGVRV 196
Query 195 FDIISKQRIT----NVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASE 250
+D+ + + VP + R + + C L W + TL+IGW +++VC +++R++ E
Sbjct 197 YDLNERCSLGLIKWEVPPQE---RLENFRCHLRWSNKHTLLIGWVDTIRVCVIRKRNSIE 253
Query 251 MR--DLPSRYVEIVSQFETEFYISGLAPL-CDQLVVLSYVKEISEKTEREYCARPRLDII 307
+LP V+ +S F+T FY+ GLAPL QLVVL + KE K+ RP L +I
Sbjct 254 ASTGNLPVYIVDPISTFQTTFYVCGLAPLSAKQLVVLGFRKE---KSSCFKALRPVLCVI 310
Query 308 QPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQDDHID 367
+ EEI +D+LT+RGF+E DY L E+ FYIV+P+D+VVA + DD I+
Sbjct 311 EYKMNNSEEICTDSLTLRGFEEYTVNDYSLGGIIEENRFYIVAPKDIVVASLIETDDRIE 370
Query 368 WLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAA 427
WL++ K+EEA+ E+ N +L + YINHL+ YD AA+ C ++LG +
Sbjct 371 WLIKHSKFEEAM---ELISANGGNVPVLSVAKLYINHLLALKKYDDAAKLCLRMLGNDKV 427
Query 428 LWEYEVYKFKEIGQLKAISPYLPRGDPV-LKPLIYEMILHEFLESDYEGFATLIREWPGD 486
LWE EV+KF + QL+++S YLP D L P +YEM+L+EFL+ D GF LI+EWP
Sbjct 428 LWEEEVFKFVKCQQLRSVSAYLPTSDECKLDPHVYEMVLYEFLKFDVCGFLNLIKEWPSH 487
Query 487 LYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKH 546
LY+ ++ A+ D+ +K N+ LL++LA LY+Y ++ +AL +YL L++KDVFQLI ++
Sbjct 488 LYDGLAVINAIHDNFRKHYANQ-LLESLALLYSYQGDFESALRMYLKLQNKDVFQLIRRY 546
Query 547 NLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDH 606
L+ I I+ L+ D + A ++LLD + KI + VV +LE E + YL L K+D
Sbjct 547 ELYDVISKLIIPLIQLDRDCAFEILLDKK-KIKTEIVVHQLEHNQEYLYWYLDSLLKKDP 605
Query 607 HKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMG-- 664
+ +K ISLYA +DR LLPFL+ S +++AL IC+Q NF E VYLL MG
Sbjct 606 S--NVFQKKLISLYAIFDRNKLLPFLKRSKDYDIQEALVICKQENFYPEIVYLLGCMGGV 663
Query 665 NSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPI 724
+ AL +I+ + D++ AIEF KE DD +LW LI P +T +L+ I + P
Sbjct 664 EASEALNIIIHRIRDIEMAIEFCKEHDDSDLWNALINEFSKHPEIVTKVLDGIVDYFSPA 723
Query 725 LLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVL 784
+++ +IK G IPNLR SL+K+L+ YNLQ + ++I + D + ++ TQ +G
Sbjct 724 VVVGKIKMGQNIPNLRQSLIKMLRHYNLQGEILSSAQQIQLNDYFEIHSEIVTTQRRGQQ 783
Query 785 VDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICS 839
V E +C C P+L + + ++ C H++HK C+ + + CN C+
Sbjct 784 VSYEQLCSLCHRPVLMA-GTHLYCIIRLECGHVYHKPCIQGELLKN----CNECN 833
>sp|Q19954|VPS41_CAEEL Vacuolar protein sorting-associated protein
41 homolog OS=Caenorhabditis elegans OX=6239 GN=vps-41
PE=3 SV=4
Length=901
Score = 882 bits (2279), Expect = 0.0, Method: Composition-based stats.
Identities = 250/888 (28%), Positives = 446/888 (50%), Gaps = 66/888 (7%)
Query 5 EEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAA-SCMTVHDKFLALGTH 63
E + +T++ ++E EP+ KYERL T K A + + +HDKF+A+GT
Sbjct 18 ENSYHDDVTFNTED--DDEPPLEPRFKYERLKGEETLPFMKTATFTSIDLHDKFIAIGTA 75
Query 64 YGKVYLLDVQGNITQKFD-VSPVK-----INQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
G +Y+LD G FD V P+K ++++ DE+G ++ C+ D K+ V G+ +
Sbjct 76 TGLIYILDHHG--YGNFDSVPPLKPHRCAVSKVKFDETGSYVLSCANDSKIVVSGV-GND 132
Query 118 EFHETFDCPI--KIIAVHPHFVRS-SCKQFVTGGKKLLLFERSWMNRWKSAVLHEG---E 171
+ T + + K I P F+R S F+ G + L+L+E+ M ++K++ L+ G +
Sbjct 133 KLCCTINIQVMPKSIYFSPDFIRQQSGHCFIMGERNLVLYEKR-MFQYKASSLYSGSERD 191
Query 172 GNIRSVKWRGHLIAWANNMGVKIFDIISKQRITNV-PRDDIS-LRPDMYPCSLCWKDNVT 229
G I W +LIA+ N+ G ++++ +++ IT+V P D+ +R P W
Sbjct 192 GFIHCCSWNENLIAFTNDTGTRVYERGAERIITSVQPSHDVDRVRSSRSPPKHTWMPENN 251
Query 230 LIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQF-------------ETEFYISGLA- 275
L+IGW +V + +++ + ++ ++ VS F E ++ GL
Sbjct 252 LVIGWADTVTILKIRDDDGVKKGEV--HHIFHVSMFICGISYIPESGIDNMELFLVGLQL 309
Query 276 ---PLCDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSETCEEISSDALTVRGFQENEC 332
D V+S V ++ E C + +I+PL E+ S+ + N
Sbjct 310 EGEDFDDCASVISTVTTLT-ALESSACTILKTSVIRPLGLKEFELQSEDMIESVKLSNHT 368
Query 333 RDYHLEYSEGESL--FYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAE-----IS 385
Y + L ++I++ + +++A +D I W L+ K Y+EAL A+ +S
Sbjct 369 LPYMIHGLGIPYLATYFILTTKHIIMAVPYGPEDGIRWRLKYKLYDEALDMAKHNADLLS 428
Query 386 QKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAI 445
+ ++ K+ G I + AA + I G+ WE+ V +F+E+ +
Sbjct 429 KTDLSPKKV---GRMIIEGYLTGKRARAAASRLPLICGECKEEWEWAVNQFEEVKLCTLL 485
Query 446 SPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKK-- 503
+ LP G P L P Y+ +L L ++ + F L++ W DLY S I+ + +++
Sbjct 486 AEVLPDGTPTLDPECYQKVLIACLFNNVKQFRKLVQTWSPDLYMTSFIIDRTQWRIQQIS 545
Query 504 --------DSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDK 555
D + L+ LA LY Y++ Y +AL+I ++ + +F +I KH LF +KD+
Sbjct 546 KSGNLADVDETERVLMDALAHLYLYERKYESALKILMSCQDFQIFNVIDKHQLFDLVKDQ 605
Query 556 IVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEK 615
I LM+ +SE+A+ +LLDN D + V+E++ +P+LQ YL KL R+ +G + +K
Sbjct 606 ITELMNINSERALRLLLDNADSVEPSFVMEKIGRQPKLQLAYLTKLMSRN--EGTEFADK 663
Query 616 QISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIME 675
+ LYAEYD+ LLPFLR + + + KA ++C + ++EET+YLL++ GN A+KM++
Sbjct 664 AVQLYAEYDQKKLLPFLRKNANYNVNKARKLCSDKGYIEETIYLLAKSGNHYDAVKMMVR 723
Query 676 ELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGME 735
E +++K I++ K+Q+D +LW L+ + P + L+ +DP+L++ ++ + +
Sbjct 724 EYRNMEKVIDYCKDQNDPDLWIHLLGVVAEFPAHFSQLIIEASNCLDPLLIMDKLPDDSD 783
Query 736 IPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCL 795
IPNL ++L K+L DY L++ C + D L + + + V V+ + C C
Sbjct 784 IPNLSEALDKLLVDYTNHAELQQCCYDSTLNDLNVLTQGLISAADESVSVNIVSRCSLCA 843
Query 796 SPILPSD--AAKPFS-VVVFHCRHMFHKECLPMPSMNSAAQFCNICSA 840
I+ S+ K FS + VF C H+FH C + +C A
Sbjct 844 QIIINSNQETTKKFSDIKVFKCGHIFHLACSTSEMERRQSIEEGLCIA 891
>sp|Q618H8|VPS41_CAEBR Vacuolar protein sorting-associated protein
41 homolog OS=Caenorhabditis briggsae OX=6238 GN=vps-41
PE=3 SV=1
Length=898
Score = 874 bits (2257), Expect = 0.0, Method: Composition-based stats.
Identities = 252/890 (28%), Positives = 438/890 (49%), Gaps = 74/890 (8%)
Query 7 QETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAA-SCMTVHDKFLALGTHYG 65
+++G + +T++ E+E+ EP+ KYERL T K A + + +HDKF+A+GT G
Sbjct 17 EDSGDITRTTED--EDEAPLEPRFKYERLEGESTLPFMKTATFTSIDLHDKFIAIGTASG 74
Query 66 KVYLLDVQGNITQKFD-VSPVK-----INQISLDESGEHMGVCSEDGKVQVFGLYSGEEF 119
+Y+LD G FD V P+K ++++ DE+G ++ C+ D K+ V G+ ++
Sbjct 75 LIYILDHHG--YGNFDSVPPLKPHRCAVSKLKFDETGSYILSCANDSKLVVSGI-GNDKL 131
Query 120 HETFDCPI--KIIAVHPHFVRS-SCKQFVTGGKKLLLFERSWMNRWKSAVLHEG---EGN 173
T + + K I P F+R S F+ G + L+L+E+ + ++K++ L+ G +G
Sbjct 132 CCTVNIQVMPKSICFSPDFIRQQSGHCFIMGERNLVLYEKR-LFQYKASNLYSGSERDGF 190
Query 174 IRSVKWRGHLIAWANNMGVKIFDIISKQRITNV-PRDDIS-LRPDMYPCSLCWKDNVTLI 231
I W +LIA+ N+ G ++++ +++ +T+V P D+ +R P W TL+
Sbjct 191 IHCCSWNDNLIAFTNDTGTRVYERGTEKILTSVQPTHDVDRVRSSRCPPKHMWMSENTLV 250
Query 232 IGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAPLCDQ-------LVVL 284
IGW +V V +K R EI F +ISG++ L LV L
Sbjct 251 IGWADTVTVLKIKGNEGM-------RKGEIHHIFHVSMFISGISYLPKNGSDYELFLVGL 303
Query 285 -----------SYVKEISEKTEREYCARPRL--DIIQPLSETCEEISSDALTVRGFQENE 331
S + ++ T E A L +I+PL E+ S+ V
Sbjct 304 QMEGEDFDDCASVMSTMTTLTAMESSATATLKTCVIRPLGLKDYELQSEDEIVNIRLSTH 363
Query 332 CRDYHLEYSEGESL--FYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAE-----I 384
Y + L ++I++ + +++A +D I W L+ K Y EA A+ +
Sbjct 364 TLPYMIHGLGIPYLSTYFILTTKQIIMAVPYGPEDGIKWRLQYKLYTEAFEMAKEHADML 423
Query 385 SQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKA 444
++ ++ K+ G I +E +AA I G WE+ V +F +
Sbjct 424 AKTDVSPKKV---GRKIIEGYLESKKARVAASWLSSICGDCKEEWEWAVDRFHDAKMSTL 480
Query 445 ISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKD 504
+ LP P L P YE +L L ++ + F L++ W DLY S I+ + +++
Sbjct 481 LGDVLPDSKPRLDPSAYEKVLLASLFNNVKLFRRLVQTWSPDLYMTSTIIDQTQWRIQQI 540
Query 505 SQN----------KTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKD 554
S++ K L+ LA LY Y++ Y +AL+I + + +F +I KH LF +KD
Sbjct 541 SKSEDIEDVEEVEKILMDALAHLYLYERKYESALKILMICQDFQIFNVIDKHQLFDLVKD 600
Query 555 KIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHE 614
+I LM+ +SE+A+ +LLDN D + V+ ++ +P+LQ YL KL R+ +G + +
Sbjct 601 QISDLMNINSERALRLLLDNADSVEPSFVMAKINGQPKLQLAYLTKLMSRN--EGIEFAD 658
Query 615 KQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIM 674
K + LYA++++ LLPFL+ + + + KA ++C R FVEET++LL++ GN A+KM++
Sbjct 659 KAVQLYADHEKKKLLPFLKKNVNYNVTKARKLCSDRGFVEETIFLLAKSGNHYEAVKMMV 718
Query 675 EELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGM 734
E +++K I + K+Q+D +LW L+ D P + L+ +DPIL++ ++ + +
Sbjct 719 REYKNIEKVIAYCKDQNDRDLWIHLLEVVADFPTHFSQLIIEASNCLDPILIMDKLPDDV 778
Query 735 EIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESC 794
+IPNL ++L K+L D+ + L++ C + D L + K V V C C
Sbjct 779 DIPNLSEALEKLLTDFTNYVELQQCCYDSTLNDLHVLTNNLMLASDKSVSVSLMTRCSLC 838
Query 795 LSPILPSDA---AKPFS-VVVFHCRHMFHKECLPMPSMNSAAQFCNICSA 840
I+ + + F+ + VF C H+FH C IC A
Sbjct 839 SQVIMNTGQDMIPRKFNDIKVFKCGHIFHLTCSASEIDRRQMIEDGICIA 888
>sp|Q9P7N3|VPS41_SCHPO Vacuolar protein sorting-associated protein
41 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
OX=284812 GN=vps41 PE=3 SV=2
Length=871
Score = 842 bits (2174), Expect = 0.0, Method: Composition-based stats.
Identities = 225/772 (29%), Positives = 401/772 (52%), Gaps = 24/772 (3%)
Query 28 PKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKI 87
PKL YER++ D S + + G+H G +Y+ G + +K + +
Sbjct 24 PKLIYERITEKFQGCFMNDTISACAISKEHFFFGSHNGAIYIYQKNGILLRKMILHSASV 83
Query 88 NQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTG 147
+S+D E++ CS DGK+ + + + E F P+ +A+ P++ S +Q ++G
Sbjct 84 VDLSVDLESENLASCSMDGKMIISNITTRETTVHDFKRPLLSVAIDPYYSTRSSRQVLSG 143
Query 148 GK--KLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITN 205
G+ K++L E+ W+ K VL G + + W IAWA+++G+ ++ + +
Sbjct 144 GRAGKVVLSEKGWLGN-KDTVLQADCGAVYKISWYTTYIAWASDLGITVYSTEFGKVLGR 202
Query 206 VPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQF 265
+ +++P L W+ L+IGW + + S++ + + +LP + + +
Sbjct 203 LEPPKRLPNDEIFPYQLFWQSESRLVIGWSDQIMIVSIQRSNVA--NELP--KISLQALL 258
Query 266 ETEFYISGLAPLCDQLVVLSYVKEISEKT-----EREYCARPRLDIIQPLSETCEEISSD 320
E + +SG+ L ++ L+Y+ + + T +R RP L +I + +E+ D
Sbjct 259 EIDSIVSGVLMLGFNILTLAYIANVEDFTSAIPSQRIEGCRPELRLID---SSFKELCGD 315
Query 321 ALTVRGFQENECRDYHL-EYSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEAL 379
A+ + + + DYHL S +++SP D+V +ER+Q DH+ +L+ K+ Y EA+
Sbjct 316 AIGLANYSRLQPSDYHLLPDPSSNSHSFVISPNDIVYVRERNQIDHVKYLVSKEMYAEAI 375
Query 380 MAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEI 439
A + + +I ++ YI HL+ +G Y A + N A WE V+ F E
Sbjct 376 DAVKKLPEIPPSLQISELAKKYIFHLLGKGQYKEAGMVIPSLYNDNLAEWEQWVFVFAEN 435
Query 440 GQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRD 499
L+ I+ +LP G+ L PL+YEMIL ++L +D F + EWP LY+ S I A
Sbjct 436 DHLEDIADFLPTGENHLSPLVYEMILAQYLATDERTFNKKLHEWPTMLYSVSTIRNATLK 495
Query 500 HLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLL 559
K++ ++ TL ++LA LY D +A +YL L + LI +HNL+ + ++LL
Sbjct 496 KFKENQKSSTLTESLAFLYLEDNMPIDAFHLYLKLHSELCIDLILQHNLYDEARASVLLL 555
Query 560 MDFDSE-KAVD-------MLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQR 611
M S+ K+ D ML+ + ++V+ ++ P+ + Y + +
Sbjct 556 MLISSKGKSSDTKSAMSSMLVQHVHSFPPQEVIMQIHSVPQFLYEYFCEFELMYPNSLME 615
Query 612 YHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALK 671
Y + ++ ++AE+DR FL ++ L+ A +IC+Q N+++E VY+L RMGN++ AL
Sbjct 616 YGDLKLDVFAEFDRKRFFDFLVNTQCYSLDHAAQICKQYNYLDELVYILGRMGNNKEALM 675
Query 672 MIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIK 731
+I+ EL D+ +AI + KEQ D ELW+DLI YS+DKP FI LL NIGT + L+ +I
Sbjct 676 LIINELLDIGRAIRYVKEQADRELWDDLISYSLDKPEFICTLLENIGTDENARNLLSKIP 735
Query 732 EGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGV 783
G ++P+++ S+ K+L D+ Q+ L + C K+ +S+S+ K + G+
Sbjct 736 PGTKLPHMKKSISKLLADHQSQVQLYQSCYKLFKNESISMAIKYREQEQSGL 787
>sp|P38959|VPS41_YEAST Vacuolar protein sorting-associated protein
41 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=VPS41 PE=1 SV=2
Length=992
Score = 711 bits (1834), Expect = 0.0, Method: Composition-based stats.
Identities = 215/898 (24%), Positives = 388/898 (43%), Gaps = 149/898 (17%)
Query 28 PKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFD-VSPVK 86
P LKY R+S Q+D+ S D F A GTH G ++L T F+ + +K
Sbjct 99 PLLKYTRISQLPKNFFQRDSISSCLFGDTFFAFGTHSGILHL------TTCAFEPIKTIK 152
Query 87 INQ---ISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE-TFDCPIKIIAVHPHFVRSSCK 142
++ + ++ G++ S DG V + + + + F PI +A+H +F + +
Sbjct 153 CHRSSILCINTDGKYFATGSIDGTVIIGSMDDPQNITQYDFKRPINSVALHSNF--QASR 210
Query 143 QFVTGG--KKLLLFERSWMNRWKSAVLH--------------EGEGNIRSVKWRGHLIAW 186
FV+GG ++L +R+W+ VL+ + +G I + G LI W
Sbjct 211 MFVSGGMAGDVVLSQRNWLGNRIDIVLNKKKKKKTRKDDLSSDMKGPIMGIYTMGDLILW 270
Query 187 ANNMGVKIFDIISKQRITNVPRD-----DISLRPDMYPCSLCWKDNVTLIIGWGTSV--- 238
++ G+ D+ ++ ++ N+P +RPD++ + + ++ ++IGWG+++
Sbjct 271 MDDDGITFCDVPTRSQLLNIPFPSRIFNVQDVRPDLFRPHVHFLESDRVVIGWGSNIWLF 330
Query 239 KVCSVKERHASE------------------------------MRDLPSRYVEIVSQFETE 268
KV K+ ++ + R P + VE+ F
Sbjct 331 KVSFTKDSNSIKSGDSNSQSNNMSHFNPTTNIGSLLSSAASSFRGTPDKKVELECHFTVS 390
Query 269 FYISGLAPLCD-QLVVLSYVKEISE--------KTEREYCARPR----------LDIIQP 309
I+GLA D QL+ L + +I E K + + RP L I+
Sbjct 391 MLITGLASFKDDQLLCLGFDIDIEEEATIDEDMKEGKNFSKRPENLLAKGNAPELKIVDL 450
Query 310 LSETCEEISSDALTVRGFQENECRDYHL--EYSEGESLFYIVSPRDVVVAKERDQDDHID 367
+EI +D + ++ +++ DYHL + +Y++S D + +E DH D
Sbjct 451 F--NGDEIYNDEVIMKNYEKLSINDYHLGKHIDKTTPEYYLISSNDAIRVQELSLKDHFD 508
Query 368 WLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAA 427
W +E+K+Y +A +I + I + IGL ++N LV + D+ I +
Sbjct 509 WFMERKQYYKAW---KIGKYVIGSEERFSIGLKFLNSLVTKKDWGTLVDHLNIIFEETLN 565
Query 428 LWEYEVYKFKEI---------------GQLKAISPYLPRGDPVLKPLIYEMILHEFLESD 472
+ Y + G + I+P +P+ P L+ +Y+ +LH FL +D
Sbjct 566 SLDSNSYDVTQNVLKEWADIIEILITSGNIVEIAPLIPKK-PALRKSVYDDVLHYFLAND 624
Query 473 Y-EGFATLIREWPGDLYNNSVIVQAVRDHL----------KKDSQNKTLLKTLAELYTYD 521
F I +W L++ + + + K++ N T L LY +
Sbjct 625 MINKFHEYITKWDLKLFSVEDFEEELETRIEAASEPTASSKEEGSNITYRTELVHLYLKE 684
Query 522 KNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIV--LLMDFDSE-------------- 565
Y A+ L + +I NL D+IV +L+ + E
Sbjct 685 NKYTKAIPHLLKAKDLRALTIIKIQNLLPQYLDQIVDIILLPYKGEISHISKLSIFEIQT 744
Query 566 ---KAVDMLLDNEDKISIKKVVEELEDRP-----ELQHVYLHKLFKRDHHKGQRYHEKQ- 616
K +D+L +N IS+ ++ E E ++ YL K D +E Q
Sbjct 745 IFNKPIDLLFENRHTISVARIYEIFEHDCPKSFKKILFCYLIKFLDTDDSFMISPYENQL 804
Query 617 ISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQR-NFVEETVYLLSRMGNSRSALKMIME 675
I LY+EYDR +LLPFL+ + +E A+E+C + E +YL ++G ++ AL +I++
Sbjct 805 IELYSEYDRQSLLPFLQKHNNYNVESAIEVCSSKLGLYNELIYLWGKIGETKKALSLIID 864
Query 676 ELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPIL-LIHRIKEGM 734
EL + AI+F K D ELWE +I YS+DKP F +L + L +I + + +
Sbjct 865 ELKNPQLAIDFVKNWGDSELWEFMINYSLDKPNFTKAILTCSDETSEIYLKVIRGMSDDL 924
Query 735 EIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGV--LVDEENI 790
+I NL+D + I+Q+ +L + +R+ I+ ++ + + + +G VDE +I
Sbjct 925 QIDNLQDIIKHIVQENSLSLEVRDNILVIINDETKKFANEFLKIRSQGKLFQVDESDI 982
>sp|Q24314|VPS18_DROME Vacuolar protein sorting-associated protein
18 homolog OS=Drosophila melanogaster OX=7227 GN=dor PE=1
SV=3
Length=1002
Score = 231 bits (588), Expect = 3e-62, Method: Composition-based stats.
Identities = 72/322 (22%), Positives = 135/322 (42%), Gaps = 45/322 (14%)
Query 524 YGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKV 583
Y AL+ + R+ ++F + + I L + VD L+ ++ ++K+
Sbjct 615 YAEALQTLINQRNPELF--------YKYAPELITRL----PKPTVDALMAQGSRLEVEKL 662
Query 584 VEEL------EDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFL----R 633
V L E R + Q YL + + H + LYAE++ L+ +L R
Sbjct 663 VPTLIIMENREQREQTQR-YLEFAIYKLNTTNDAIHNFLLHLYAEHEPKLLMKYLEIQGR 721
Query 634 DST--HCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQD 691
D + H + A ++C + E V+L + SA+ + + D+ A E A
Sbjct 722 DESLVHYDIYYAHKVCTDLDVKEARVFLECMLRKWISAVDLALT--FDMKLAKETASRPS 779
Query 692 D----GELWEDLILYSIDKPPFITGLLNNIGTHVDPILL---IHRIKEGMEIPNLRDSLV 744
D +LW + + I + LN + D + + + + +I N ++++
Sbjct 780 DSKIRRKLWLRIAYHDIKGTNDVKKALN-LLKECDLLRIEDLLPFFADFEKIDNFKEAIC 838
Query 745 KILQDYN--LQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSD 802
L+DYN +Q L RE + D ++ ++ + + + V+ ++ CE C +L
Sbjct 839 DALRDYNQRIQELQREMAETTEQTDRVT--AELQQLRQHSLTVESQDTCEICEMMLL--- 893
Query 803 AAKPFSVVVFHCRHMFHKECLP 824
KPF +F C H FH +CL
Sbjct 894 -VKPF--FIFICGHKFHSDCLE 912
>sp|P59015|VPS18_DANRE Vacuolar protein sorting-associated protein
18 homolog OS=Danio rerio OX=7955 GN=vps18 PE=2 SV=2
Length=974
Score = 140 bits (353), Expect = 9e-33, Method: Composition-based stats.
Identities = 83/476 (17%), Positives = 172/476 (36%), Gaps = 82/476 (17%)
Query 403 NHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYE 462
H + Y +A K +E KF E Q +A+ +L + LKP
Sbjct 431 EHCFQNKRYLESA----KCYALTQNYFEEIALKFIEAKQEEALKEFLIKKLVNLKPS--- 483
Query 463 MILHEFLESDYEGFATLIREWPGDLYNN-----------SVIVQAVRDHLKK-------- 503
+ TL+ W +LY N + R+ +
Sbjct 484 ----------EKTQITLLVTWLTELYLNRLGQLEADEGKQHLFLETREEFRTFLKSPKHK 533
Query 504 ----DSQNKTL--------LKTLAELYTYDKNYGNALEIYLTLRHKD---VFQLIHKHNL 548
++++ + + ++Y + Y +H D ++ KH
Sbjct 534 DCFYNNRSTIYDLLASHGDVDNMVYFSVIMQDYERVISHY--CQHDDYSAALDVLSKHCD 591
Query 549 FSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPEL--------QHVYLHK 600
+LM +K VD + +++ K ++ L + ++ Y+
Sbjct 592 DKLFYKFSPVLMQHIPKKVVDAWIQMGNRLDPKNLIPALVNYSQMGSMQQINETIRYMEF 651
Query 601 LFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLR------DSTHCPLEKALEICQQRNFVE 654
K + H +SLYA++ LL +L H L+ AL +C + +++
Sbjct 652 CVYELDVKEEAIHNYLLSLYAKHKPDALLWYLEQAGTHVSDIHYDLKYALRLCSEHGYLQ 711
Query 655 ETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGE-----LWEDLILYSIDKPPF 709
V + M A+ + ++ DVD A A +D E LW + + + +
Sbjct 712 ACVLVYKIMELYEEAVDLALK--VDVDLAKSCADLPEDDEELRKKLWLKIARHVVQEEKD 769
Query 710 ITGLLNNIGTH--VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVAD 767
+ +N + + + ++ + + I + ++++ L++YN I + +
Sbjct 770 VKKAMNCLSSCNLLKIEDILPFFPDFVTIDHFKEAICSSLEEYNKHIEELKQEMEEATES 829
Query 768 SLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECL 823
+ + + + + K +V+ + C +C P+L +PF +F C HMFH +CL
Sbjct 830 AKRIREDIQEMRNKYGVVESQEKCATCDFPLLN----RPF--YLFLCGHMFHYDCL 879
>sp|Q8R307|VPS18_MOUSE Vacuolar protein sorting-associated protein
18 homolog OS=Mus musculus OX=10090 GN=Vps18 PE=1 SV=2
Length=973
Score = 125 bits (315), Expect = 3e-28, Method: Composition-based stats.
Identities = 59/319 (18%), Positives = 127/319 (40%), Gaps = 37/319 (12%)
Query 524 YGNALEIYLTLRHKDVF----QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKIS 579
Y AL + R +F ++ +H + I + D+ + + L++
Sbjct 579 YEEALAVLARHRDPQLFYKFSPILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGE 638
Query 580 IKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDS---- 635
++V + + Y+ Q H +SLYA +LL +L +
Sbjct 639 AQQVSQAIR--------YMEFCVNVLGETEQAIHNYLLSLYARGQPASLLAYLEQAGASP 690
Query 636 --THCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDG 693
H L+ AL +C + V++ + A+ + ++ DVD A + A ++
Sbjct 691 HRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQ--VDVDLAKQCADLPEED 748
Query 694 E-----LWEDLILYSIDKPPFITGLLNNIGTH--VDPILLIHRIKEGMEIPNLRDSLVKI 746
E LW + + + + + + + + + ++ + + I + ++++
Sbjct 749 EELRKKLWLKIARHVVQEEEDVQTAMACLASCPLLKIEDVLPFFPDFVTIDHFKEAICSS 808
Query 747 LQDYN--LQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAA 804
L+ YN +Q L RE + A + + + + + V+ ++ C +C P+L
Sbjct 809 LKAYNHHIQELQREMEEATASAQRIR--RDLQELRGRYGTVEPQDKCSTCDFPLLN---- 862
Query 805 KPFSVVVFHCRHMFHKECL 823
+PF +F C HMFH +CL
Sbjct 863 RPF--YLFLCGHMFHADCL 879
>sp|Q9P253|VPS18_HUMAN Vacuolar protein sorting-associated protein
18 homolog OS=Homo sapiens OX=9606 GN=VPS18 PE=1 SV=2
Length=973
Score = 125 bits (315), Expect = 4e-28, Method: Composition-based stats.
Identities = 59/319 (18%), Positives = 128/319 (40%), Gaps = 37/319 (12%)
Query 524 YGNALEIYLTLRHKDVF----QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKIS 579
Y AL + R +F ++ +H + I + D+ + + L++
Sbjct 579 YEEALAVLARHRDPQLFYKFSPILIRHIPRQLVDAWIEMGSRLDARQLIPALVNYSQGGE 638
Query 580 IKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDS---- 635
+++V + + Y+ Q H +SLYA +LL +L +
Sbjct 639 VQQVSQAIR--------YMEFCVNVLGETEQAIHNYLLSLYARGRPDSLLAYLEQAGASP 690
Query 636 --THCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDG 693
H L+ AL +C + V++ + A+ + ++ DVD A + A ++
Sbjct 691 HRVHYDLKYALRLCAEHGHHRACVHVYKVLELYEEAVDLALQ--VDVDLAKQCADLPEED 748
Query 694 E-----LWEDLILYSIDKPPFITGLLNNIGTH--VDPILLIHRIKEGMEIPNLRDSLVKI 746
E LW + + + + + + + + + ++ + + I + ++++
Sbjct 749 EELRKKLWLKIARHVVQEEEDVQTAMACLASCPLLKIEDVLPFFPDFVTIDHFKEAICSS 808
Query 747 LQDYN--LQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAA 804
L+ YN +Q L RE + A + + + + + V+ ++ C +C P+L
Sbjct 809 LKAYNHHIQELQREMEEATASAQRIR--RDLQELRGRYGTVEPQDKCATCDFPLLN---- 862
Query 805 KPFSVVVFHCRHMFHKECL 823
+PF +F C HMFH +CL
Sbjct 863 RPF--YLFLCGHMFHADCL 879
>sp|F4IDS7|VPS18_ARATH Vacuolar sorting protein 18 OS=Arabidopsis
thaliana OX=3702 GN=VPS18 PE=1 SV=1
Length=988
Score = 104 bits (259), Expect = 2e-21, Method: Composition-based stats.
Identities = 93/553 (17%), Positives = 186/553 (34%), Gaps = 77/553 (14%)
Query 337 LEYSEGESLFYIVSPRDVVVAKERDQ-DDHIDWLLEKKKYEEALMAAEISQKNIKRHKIL 395
L ++FY + D+ D L+ K Y AL +
Sbjct 338 LCSDASANVFYAYDQNSIFQVSVIDEGRDMWKVYLDLKVYAAALANCR------DPLQRD 391
Query 396 DIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPV 455
+ L +Y AA KI +E KF I + +A+ +L
Sbjct 392 QVYLVQAESAFTDKEYLRAASFYAKI--NYVISFEEVTLKFISINEPEALRTFLLHKLDN 449
Query 456 LKP--------------LIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHL 501
L +Y ++ L D E+ + + +D L
Sbjct 450 LSKDDKCQITMISTWATELYLDKINRLLLEDDTAIENRDSEYHSVIQEFRAFMSDCKDEL 509
Query 502 KKDSQNKTL-----LKTLAELYTYDKNYGNALEIYLTL-RHKDVFQLIHKHNLFSSIKDK 555
+ + K L ++ L + Y + Y+ K +++ K ++ ++ +
Sbjct 510 DEATTVKILESYGRVEELVYFANLKEQYEIVVLHYIQQGEAKKALEVLQKSSVSVELQYQ 569
Query 556 IVL-LMDFDSEKAVDMLLDNEDKISIKKVV---------EELEDRPELQHVYLHKLFKRD 605
L+ D+ + V+ + N++ ++ ++++ ++ YL R
Sbjct 570 FAPELIMLDAYETVESWMANKN-LNPRRLITAMMRYSSGPHAKNETHEVIKYLEFCVHRL 628
Query 606 HHKGQRYHEKQISLYA-EYDRPNLLPFLR----------DSTHCPLEKALEICQQRNFVE 654
H++ H +SLYA + D LL FL+ + AL +C +
Sbjct 629 HNEDPGIHSLLLSLYAKQEDDGALLRFLQCKFGKGRENGPEFFYDPKYALRLCLKERRTR 688
Query 655 ETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGE-----LWEDLILYSID---- 705
V++ S M A+ + ++ D + A+ A + +D E LW + + +
Sbjct 689 ACVHIYSMMSMHEEAVALALQ--IDPELAMAEADKVEDDEDLRKKLWLMVAKHVVKQEKG 746
Query 706 -KPPFITGL---LNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCK 761
K I L + ++ + I + ++++ L+DYN QI +
Sbjct 747 AKRENIRKAIAFLKETDGLLKIEDILPFFPDFALIDDFKEAICSSLEDYNKQIEQLKEEM 806
Query 762 KILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDA----AKPFS-------VV 810
+ ++ + + ++D + C C IL A+ +S
Sbjct 807 NDATRGADNIRNDISALTQRYAVIDRDEECGVCKRKILMMSGDFRMAQGYSSAGPLAPFY 866
Query 811 VFHCRHMFHKECL 823
VF C H FH +CL
Sbjct 867 VFPCGHSFHAQCL 879
>sp|Q23194|VPS18_CAEEL Vacuolar protein sorting-associated protein
18 homolog OS=Caenorhabditis elegans OX=6239 GN=vps-18
PE=1 SV=4
Length=1026
Score = 95.9 bits (237), Expect = 7e-19, Method: Composition-based stats.
Identities = 95/548 (17%), Positives = 200/548 (36%), Gaps = 91/548 (17%)
Query 357 AKERDQDDHIDWL----LEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYD 412
A + +D ++ L++ +Y++AL A ++ I+ + + + ++ ++
Sbjct 397 AMKYGTNDEARYIWKTYLDRGEYQKALQIAR-TRVAIEPDALEMVLRKQADFYIQEKNFT 455
Query 413 IAARKCQKILGKNAALWEYEVYKFKEIGQLKAIS--PYLPRGDPVL---KPLIYEMILHE 467
AA IL +++ +E V KF + + L + L + I L
Sbjct 456 AAAE----ILAQSSEPFESVVLKFLTNSSERKMGLKTLLDKKLERLTRHEDKIRRDALVM 511
Query 468 FLES----DYEGFATLIREWP-----GDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELY 518
+L + + L P L + + VQ +T + +
Sbjct 512 WLLNVQLEELAEMRRLKNSNPDPAFVEKLRDTTDHVQRYFMRKNVIESIQTNRDAVYRMC 571
Query 519 TYDKNYG------NALE--------IYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDS 564
++ NA++ + L ++ +V +++ + + LL++
Sbjct 572 VAHADFEMQLFFANAVKDLRTVIDILMLREQYFEVLEVLKNQRISELTYEMCPLLIEHIP 631
Query 565 EKAVDMLLDNEDKISIKKVVEELEDRPELQHV------YLHKLFK------RDHHKGQRY 612
++ + L+ N+D+IS +K+ L + + YL FK ++
Sbjct 632 KQVIVYLIQNQDQISPQKLTPCLSLCVKNMEMAIPAIKYLEAQFKGTQTISQNPQNLANL 691
Query 613 HEKQISLYAEYDRPNLLPFL------RDSTHCPLEKALEICQQRNFVEETVYLLSRMGNS 666
H I L A++ R LL +L R L+ A+ C+Q VYL G
Sbjct 692 HNIYIHLMAKFRREKLLGYLESHGTIRSDLPYELDFAMRTCEQFKIEPCVVYLFCVAGMF 751
Query 667 RSAL--------------KMIMEE-------LHDVDK--AIEFAKEQDDGE----LWEDL 699
A+ ++MEE L ++ A + +++ D + +W +
Sbjct 752 GDAVEKALGFDVDLAKKCALMMEEAEANFAWLEGMEDPAATSYIRQKLDEKAKKAIWLKI 811
Query 700 ILYSIDKPPFITG---LLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILL 756
Y + + + L+N + L+ I + + L+ +V L+ ++
Sbjct 812 GQYYVTQENNVDKCIELINESNHLLTIQDLLPIIPKFTRVGALKPIIVDFLKRNKQRLEK 871
Query 757 REGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRH 816
E K + + K + + + +V ++C C PI + + F+ V CRH
Sbjct 872 LERSMKEATEIASEIRDKQEKLKNRTTVVKPSDVCSHCARPI----SGRAFN--VHSCRH 925
Query 817 MFHKECLP 824
FH+ECL
Sbjct 926 FFHRECLE 933
>sp|Q9VRX2|VPS8_DROME Vacuolar protein sorting-associated protein
8 homolog OS=Drosophila melanogaster OX=7227 GN=Vps8 PE=1
SV=1
Length=1229
Score = 89.4 bits (220), Expect = 8e-17, Method: Composition-based stats.
Identities = 74/425 (17%), Positives = 153/425 (36%), Gaps = 46/425 (11%)
Query 449 LPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNN-SVIVQAVRDHLKKDSQN 507
LPR +L+ ++ + E + W L +N + + + L+ +
Sbjct 776 LPRDRQLLERVLSHLAQEEIANESSRQHSERENAWHELLSSNCLAEISSDEEQLRLAEKA 835
Query 508 KTLLKTLAELYTYDK--NYGNALEIYLT--LRHKDVFQLIHKH------NLFSSIKDKIV 557
K Y +K Y L+ Y+ RH+ +F + +H ++F +K +
Sbjct 836 KCY---CVVEYLLEKLERYDTILDSYIRNEARHETMFAYMERHVASPKRSIFRQLKRNLR 892
Query 558 LLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQI 617
L+ ++++ +L + + I ++++ L L +++L L R E +
Sbjct 893 ELLTINAKETTRLLSLHYPE-KINELLDNLRREENLLYLFLKCLNDRKSELEASQMELLL 951
Query 618 SLYAEYDRPNLLP-FLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEE 676
LY + + + + FLR ++ LE A+ I + + +YL + + A ++ ME
Sbjct 952 ELYCKMESSSTVEEFLRSNSGYRLENAIAIAESHHLNRSVIYLYEKQESYAKAFELSMEL 1011
Query 677 LHD----------------VDKAIEFAKEQDDGELWEDLILYSIDKPP---FITGLLNNI 717
L + +++E Q+ W L+ Y + LL+
Sbjct 1012 LKSAAGEEAAKEAQTISALLARSVETLPAQELERCWFALLQYILPHQELQSITKSLLHEA 1071
Query 718 GTHVDPILLIHRIKEGMEIP----NLRDSLVKILQDYNLQILLREGCKKILVADSLSLLK 773
H+D L+ I + +++D L+ +L + L D
Sbjct 1072 SQHIDLHNLVQLIMNTHNVSTSFGDIKDLLMGMLDSSRHKTEALRASAGALCQDLHLKFV 1131
Query 774 KMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQ 833
K ++ +G+ V C C + F C H H++C M + +
Sbjct 1132 KRYQHAHRGLWVT-TTKCSMCRQRLYDHSQVLIFGG----CGHGIHEQC--MEESETQFE 1184
Query 834 FCNIC 838
C C
Sbjct 1185 ECPRC 1189
>sp|Q9H270|VPS11_HUMAN Vacuolar protein sorting-associated protein
11 homolog OS=Homo sapiens OX=9606 GN=VPS11 PE=1 SV=1
Length=941
Score = 88.6 bits (218), Expect = 1e-16, Method: Composition-based stats.
Identities = 93/554 (17%), Positives = 195/554 (35%), Gaps = 81/554 (15%)
Query 344 SLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYIN 403
SL+ + V +E+D ++ L +K +E A+ A+ +++ + I + Y +
Sbjct 339 SLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAK--SQHLDSDGLAQIFMQYGD 396
Query 404 HLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPR-GDPVLKPLIYE 462
HL +G++D A ++ + +G Y + KF + ++ ++ YL L +
Sbjct 397 HLYSKGNHDGAVQQYIRTIG--KLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHT 454
Query 463 MILHEFLES--DYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAE---L 517
+L D I++ H ++ K L + L
Sbjct 455 TLLLNCYTKLKDSSKLEEFIKK-----------KSESEVHFDVETAIKVLRQAGYYSHAL 503
Query 518 YTYDK----------------NYGNALEIYLTLRHKDVFQLIHKHN--LFSSIKDKIVLL 559
Y + NY AL L + + ++ L I ++ L
Sbjct 504 YLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQL 563
Query 560 MDFDSEKAVDMLLDNEDKISI------KKVVEELEDRPELQHVYLHKLFKRDHHKGQRYH 613
+ L D+ + ++ + + P +L + + Q +
Sbjct 564 LKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIY 623
Query 614 EKQISL----YA-EYDRP-------NLLPFLRDSTHCPL-EKALEICQQRNFVEETVYLL 660
+ + L +A E D + L+ C + +KAL +CQ +F + +YL
Sbjct 624 DTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLY 683
Query 661 SRMGNSRSALKMIMEELHDVDKAIEFAKEQD--DGELWEDLILYSIDKPPFITGLLNNIG 718
+ G + + + I + D LWE + Y K + +
Sbjct 684 EQ-GKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVL 742
Query 719 THVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRT 778
H++ L+ + + + + + +++DY +Q L ++ ++I + + T
Sbjct 743 KHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQKQS-QQIAQDELRVRRYREETT 801
Query 779 QMK--------GVLVDEENICESCLSPI-LPSDAAKPFSVVVFHCRHMFHKECLPMPSMN 829
+++ + ++ C C S + LPS V F C H FH+ C S +
Sbjct 802 RIRQEIQELKASPKIFQKTKCSICNSALELPS--------VHFLCGHSFHQHCF--ESYS 851
Query 830 SAAQFCNICSAKNR 843
+ C C +NR
Sbjct 852 ESDADCPTCLPENR 865
Score = 49.7 bits (117), Expect = 1e-04, Method: Composition-based stats.
Identities = 46/257 (18%), Positives = 94/257 (37%), Gaps = 27/257 (11%)
Query 491 SVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKD-VFQLIHKHNLF 549
S + + V D L + L + +K+ LE+ + L +L
Sbjct 324 STVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLD 383
Query 550 SSIKDKIVLLMDF--------DSEKAVDMLLDNEDKISIKKVVEELEDRPEL--QHVYLH 599
S +I M + + + AV + K+ V+ + D + YL
Sbjct 384 SDGLAQI--FMQYGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQ 441
Query 600 KLFKRDHHKGQRYHEKQISLYAEY-DRPNLLPFLRD----STHCPLEKALEICQQRNFVE 654
L R + ++ Y + D L F++ H +E A+++ +Q +
Sbjct 442 TL-HRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYS 500
Query 655 ETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAK----EQDDGEL--WEDLILYSIDKPP 708
+YL + LK+ +E++ + +A+ + EQ + + + ++++ I P
Sbjct 501 HALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHI--PE 558
Query 709 FITGLLNNIGTHVDPIL 725
T LL + T P L
Sbjct 559 QTTQLLKGLCTDYRPSL 575
>sp|Q8R5L3|VPS39_MOUSE Vam6/Vps39-like protein OS=Mus musculus
OX=10090 GN=Vps39 PE=1 SV=1
Length=886
Score = 88.6 bits (218), Expect = 1e-16, Method: Composition-based stats.
Identities = 117/600 (20%), Positives = 193/600 (32%), Gaps = 136/600 (23%)
Query 340 SEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEI--SQKNIKRHKILDI 397
S G ++ Y+ S V I LL+ K++E AL AE+ + K+ +I I
Sbjct 289 SGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQLAEMKDDSDSEKQQQIHHI 348
Query 398 GLAYINHLVERGDYDIAA------------------RKCQKILGKNA-----------AL 428
Y +L + +D + K A
Sbjct 349 KNLYAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPTLSGAE 408
Query 429 WEYE---------------VYKFKEIGQLKAISPYL---PR--GDPVLKPLIYEMILHEF 468
E V K + + SP + P L +I +L +
Sbjct 409 LEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCY 468
Query 469 LESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNAL 528
L ++ A L+R L NN ++ LKK + L LY + AL
Sbjct 469 LHTNVALVAPLLR-----LENNHCHIEESEHVLKKAHKYS----ELIILYEKKGLHEKAL 519
Query 529 EIYLTLRHK------------DVFQLIHKHNLFSSIKDKIVLLMDF--DSEKAVDMLLDN 574
++ + K Q + NL + +L DF D K L
Sbjct 520 QVLVDQSKKANSPLKGHERTVQYLQHLGTENLHLIFSYSVWVLRDFPEDGLKIFTEDLPE 579
Query 575 EDKISIKKVVE-ELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAE----------- 622
+ + +V+ +E+ L YL + G ++H I LY E
Sbjct 580 VESLPRDRVLNFLIENFKALAIPYLEHIIHVWEETGSQFHNCLIQLYCEKVQSLMKDYLL 639
Query 623 -------------------YDRPNLLPFLRDSTHCPLEKALEICQQ--RNFVEETVYLLS 661
R LL FL S+H IC +EE LL
Sbjct 640 SLPTGKSPVPAGEEGGELGEYRQKLLMFLEISSHYD--PGRLICDFPFDGLLEERALLLG 697
Query 662 RMGNSRSALKMIMEELHDVDKAIEFAKEQDD------GELWEDLILYSIDKPPFIT---- 711
RMG AL + + L D A E+ + D +++ L+ + P
Sbjct 698 RMGKHEQALFIYVHVLKDTKMAKEYCHKHYDQNKEGNKDVYLSLLRMYLSPPSIHCLGPI 757
Query 712 ---------------GLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILL 756
+L + +D I+ + +I ++R L K+L++ +
Sbjct 758 KLELLEPQANLQAALQVLELHYSKLDTTKAINLLPANTQINDIRIFLEKVLEENAQKKRF 817
Query 757 REGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAK-PFSVVV-FHC 814
+ K +L A+ L + ++ Q ++ EE +C C I S A+ P VVV + C
Sbjct 818 NQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIGNSAFARYPNGVVVHYFC 877
>sp|Q91W86|VPS11_MOUSE Vacuolar protein sorting-associated protein
11 homolog OS=Mus musculus OX=10090 GN=Vps11 PE=1 SV=3
Length=941
Score = 87.5 bits (215), Expect = 3e-16, Method: Composition-based stats.
Identities = 95/554 (17%), Positives = 195/554 (35%), Gaps = 81/554 (15%)
Query 344 SLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYIN 403
SL+ + V +E+D ++ L +K +E A+ A+ +++ + I + Y +
Sbjct 339 SLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAK--SQHLDSDGLAQIFMQYGD 396
Query 404 HLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPR-GDPVLKPLIYE 462
HL +G++D A ++ + +G Y + KF + ++ ++ YL L +
Sbjct 397 HLYSKGNHDGAVQQYIRTIG--KLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHT 454
Query 463 MILHEFLES--DYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAE---L 517
+L D I+ H ++ K L + L
Sbjct 455 TLLLNCYTKLKDSSKLEEFIKT-----------KSESEVHFDVETAIKVLRQAGYYSHAL 503
Query 518 YTYDK----------------NYGNALEIYLTLRHKDVFQLIHKH--NLFSSIKDKIVLL 559
Y + NY AL L + + ++ L I ++ L
Sbjct 504 YLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKTLMHHIPEQTTQL 563
Query 560 MDFDSEKAVDMLLDNEDK------ISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYH 613
+ L D+ S ++ + + P +L + + Q +
Sbjct 564 LKGLCTDYRPSLEGRGDREALSCRASSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIY 623
Query 614 EKQISL----YA-EYDRP-------NLLPFLRDSTHCPL-EKALEICQQRNFVEETVYLL 660
+ + L +A E D + L+ C + +KAL +CQ +F + +YL
Sbjct 624 DTLLELRLQNWAHEKDPQAKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLY 683
Query 661 SRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGE--LWEDLILYSIDKPPFITGLLNNIG 718
+ G + + + I + + E LWE + Y K + +
Sbjct 684 EQ-GKLFQQIMHYHMQHEQYRQVIAVCERHGEQEPSLWEQALSYFARKEEDCKEYVAAVL 742
Query 719 THVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRT 778
H++ L+ + + + + + I++DY +Q L ++ ++I + + T
Sbjct 743 RHIENKSLMPPLLVVQTLAHNSTATLSIIRDYLVQKLQKQS-QQIAQDELRVRRYREETT 801
Query 779 QMK--------GVLVDEENICESCLSPI-LPSDAAKPFSVVVFHCRHMFHKECLPMPSMN 829
+++ + ++ C C S + LPS V F C H FH+ C S +
Sbjct 802 RIRQEIQELKASPKIFQKTKCSICNSALELPS--------VHFLCGHSFHQHCF--ESYS 851
Query 830 SAAQFCNICSAKNR 843
+ C C +NR
Sbjct 852 ESDADCPTCLPENR 865
>sp|Q96JC1|VPS39_HUMAN Vam6/Vps39-like protein OS=Homo sapiens
OX=9606 GN=VPS39 PE=1 SV=2
Length=886
Score = 84.4 bits (207), Expect = 2e-15, Method: Composition-based stats.
Identities = 116/600 (19%), Positives = 193/600 (32%), Gaps = 136/600 (23%)
Query 340 SEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEI--SQKNIKRHKILDI 397
S G ++ Y+ S V I LL+ K++E AL AE+ + K+ +I I
Sbjct 289 SGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQLAEMKDDSDSEKQQQIHHI 348
Query 398 GLAYINHLVERGDYDIAA------------------RKCQKILGKNA-----------AL 428
Y +L + +D + K A
Sbjct 349 KNLYAFNLFCQKRFDESMQVFAKLGTDPTHVMGLYPDLLPTDYRKQLQYPNPLPVLSGAE 408
Query 429 WEYE---------------VYKFKEIGQLKAISPYL---PR--GDPVLKPLIYEMILHEF 468
E V K + + SP + P L +I +L +
Sbjct 409 LEKAHLALIDYLTQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCY 468
Query 469 LESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNAL 528
L ++ A L+R L NN ++ LKK + L LY + AL
Sbjct 469 LHTNVALVAPLLR-----LENNHCHIEESEHVLKKAHKYS----ELIILYEKKGLHEKAL 519
Query 529 EIYLTLRHK------------DVFQLIHKHNLFSSIKDKIVLLMDF--DSEKAVDMLLDN 574
++ + K Q + NL + +L DF D K L
Sbjct 520 QVLVDQSKKANSPLKGHERTVQYLQHLGTENLHLIFSYSVWVLRDFPEDGLKIFTEDLPE 579
Query 575 EDKISIKKVVE-ELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAE----------- 622
+ + +V+ +E+ L YL + G R+H I LY E
Sbjct 580 VESLPRDRVLGFLIENFKGLAIPYLEHIIHVWEETGSRFHNCLIQLYCEKVQGLMKEYLL 639
Query 623 -------------------YDRPNLLPFLRDSTHCPLEKALEICQQ--RNFVEETVYLLS 661
R LL FL S++ IC +EE LL
Sbjct 640 SFPAGKTPVPAGEEEGELGEYRQKLLMFLEISSYYD--PGRLICDFPFDGLLEERALLLG 697
Query 662 RMGNSRSALKMIMEELHDVDKAIEFAKEQDDG------ELWEDLILYSIDKPPFIT---- 711
RMG AL + + L D A E+ + D +++ L+ + P
Sbjct 698 RMGKHEQALFIYVHILKDTRMAEEYCHKHYDRNKDGNKDVYLSLLRMYLSPPSIHCLGPI 757
Query 712 ---------------GLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILL 756
+L + +D ++ + +I ++R L K+L++ +
Sbjct 758 KLELLEPKANLQAALQVLELHHSKLDTTKALNLLPANTQINDIRIFLEKVLEENAQKKRF 817
Query 757 REGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAK-PFSVVV-FHC 814
+ K +L A+ L + ++ Q ++ EE +C C I S A+ P VVV + C
Sbjct 818 NQVLKNLLHAEFLRVQEERILHQQVKCIITEEKVCMVCKKKIGNSAFARYPNGVVVHYFC 877
>sp|Q0P5W1|VPS8_MOUSE Vacuolar protein sorting-associated protein
8 homolog OS=Mus musculus OX=10090 GN=Vps8 PE=1 SV=1
Length=1427
Score = 81.3 bits (199), Expect = 2e-14, Method: Composition-based stats.
Identities = 77/477 (16%), Positives = 167/477 (35%), Gaps = 87/477 (18%)
Query 450 PRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKT 509
P + +++ +L D + + ++ +L IVQ L + ++
Sbjct 843 PDNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRLIRMAEKAE 902
Query 510 LLKTLAELYTYDKNYGNALEIYLT--LRHKDVFQLIH------------KHNLFSSIKDK 555
+ +Y + Y ++ YL LR ++VF IH K +++ +
Sbjct 903 FYQICEFMYEREHQYDKIIDCYLHDPLREEEVFNYIHNILSIPGHSAEEKQSVWQKAMNH 962
Query 556 IVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDH--HKGQR-- 611
+ L+ KA +++ + + I+ V+ +L L +L L H Q
Sbjct 963 MEELVSLKPCKAAELVATHFSE-QIEVVIGQL-QNQLLLFKFLRSLLDPREGVHVNQELL 1020
Query 612 -----YHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNS 666
E+ I L ++ ++ L+ LE+ ++I Q+ E T YLL + G++
Sbjct 1021 QIPPHITEQFIELLCQFSPDQVIQTLQVLECYRLEETIQITQKYQLHEVTAYLLEKKGDA 1080
Query 667 RSALKMIMEELHD------------------------VDKAIEFAKE-------QDDGEL 695
A +++E L + + I + Q L
Sbjct 1081 HGAFLLLLERLQSRLQEMTRQDENTKEDILLKGVEDTMVETIALCQRNSQNLNQQQREAL 1140
Query 696 WEDLILYSIDKPPFITGLLNNIGTHVDPIL-----LIHRIKEGMEIPNLRDSLVK----- 745
W L+ ++ P ++ H + + +++ + + +P++ +++
Sbjct 1141 WFPLL-EAMMTPQKLSSSAAAPHPHCEALKSLTMQVLNSMAAFIALPSILQRILQDPIYG 1199
Query 746 -------------ILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICE 792
+L +N + L E +L D L + + +G+ +++ C
Sbjct 1200 KGKLGEIQGLILGMLDTFNYEQTLLETTASLLNQDLHWSLCNLRASVSRGLN-PKQDYCS 1258
Query 793 SCLSPILPSDAAKPFSVVVFHCRHMFHKECLPM-----PSMNSAAQFCNICSAKNRG 844
CL ++VF C H++H CL C+ CS+ N+
Sbjct 1259 ICLQQ-YKRRQEMADEIIVFSCGHLYHSFCLQSKECTLEVEGQTRWACHKCSSSNKA 1314
>sp|Q8N3P4|VPS8_HUMAN Vacuolar protein sorting-associated protein
8 homolog OS=Homo sapiens OX=9606 GN=VPS8 PE=1 SV=3
Length=1428
Score = 78.2 bits (191), Expect = 3e-13, Method: Composition-based stats.
Identities = 79/476 (17%), Positives = 168/476 (35%), Gaps = 88/476 (18%)
Query 450 PRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKT 509
P + +++ +L D + + ++ +L IVQ L + ++
Sbjct 845 PDNTLFVNRTLFDQVLEFLCSPDDDSRHSERQQVLLELLQAGGIVQFEESRLIRMAEKAE 904
Query 510 LLKTLAELYTYDKNYGNALEIYLT--LRHKDVFQLIH------------KHNLFSSIKDK 555
+ +Y + Y ++ YL LR ++VF IH K +++ D
Sbjct 905 FYQICEFMYEREHQYDKIIDCYLRDPLREEEVFNYIHNILSIPGHSAEEKQSVWQKAMDH 964
Query 556 IVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQR---- 611
I L+ KA +++ + I+ V+++L L +L L D +G
Sbjct 965 IEELVSLKPCKAAELVATHFSG-HIETVIKKL-QNQVLLFKFLRSLL--DPREGIHVNQE 1020
Query 612 -------YHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMG 664
E+ I L +++ ++ L+ LE+ ++I Q+ E T YLL + G
Sbjct 1021 LLQISPCITEQFIELLCQFNPTQVIETLQVLECYRLEETIQITQKYQLHEVTAYLLEKKG 1080
Query 665 NSRSALKMIMEEL--------------------HDVD----KAIEFAKE-------QDDG 693
+ A +++E L DV+ + I + Q
Sbjct 1081 DIHGAFLIMLERLQSKLQEVTHQGENTKEDPSLKDVEDTMVETIALCQRNSHNLNQQQRE 1140
Query 694 ELWEDLILYSIDKPPFITGLLNNIGTH---VDPILLIHRIKEGMEIPNLRDSLVK----- 745
LW L+ + + + ++ + + +++ + + +P++ +++
Sbjct 1141 ALWFPLLEAMMAPQKLSSSAIPHLHSEALKSLTMQVLNSMAAFIALPSILQRILQDPVYG 1200
Query 746 -------------ILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICE 792
+L +N + L E +L D L + + +G+ +++ C
Sbjct 1201 KGKLGEIQGLILGMLDTFNYEQTLLETTTSLLNQDLHWSLCNLRASVTRGLN-PKQDYCS 1259
Query 793 SCLSPILPSDAAKPFSVVVFHCRHMFHKECLPM-----PSMNSAAQFCNICSAKNR 843
CL ++VF C H++H CL C CS+ N+
Sbjct 1260 ICLQQ-YKRRQEMADEIIVFSCGHLYHSFCLQNKECTVEFEGQTRWTCYKCSSSNK 1314
>sp|Q8WUH2|TGFA1_HUMAN Transforming growth factor-beta receptor-associated
protein 1 OS=Homo sapiens OX=9606 GN=TGFBRAP1 PE=1
SV=1
Length=860
Score = 73.6 bits (179), Expect = 5e-12, Method: Composition-based stats.
Identities = 88/596 (15%), Positives = 198/596 (33%), Gaps = 110/596 (18%)
Query 328 QENECRDYHLEYSEG--ESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEIS 385
Q+ + + + E + + + V + + I LL ++ EEAL+ A+ +
Sbjct 277 QQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLASRRVEEALVLAKGA 336
Query 386 QKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAI 445
++NI + K + + + Q + L+ +E L ++
Sbjct 337 RRNIPKEKFQVMYRRIL-------QQAGFIQFAQLQFLEAKELFRSGQLDVRE---LISL 386
Query 446 SPYL-PRGDPVLK--PLIYEMI-LHEFLESDYEGFAT---LIREWPGDLYNNSVI----- 493
P+L P + P ++E L++ + D E A + + ++ + V
Sbjct 387 YPFLLPTSSSFTRSHPPLHEYADLNQLTQGDQEKMAKCKRFLMSYLNEVRSTEVANGYKE 446
Query 494 -VQAVRDHLKKDSQNKTLLK------------------------TLAELYTYDKNYGNAL 528
+ L ++ + +LL L LY Y+ A+
Sbjct 447 DIDTALLKLYAEADHDSLLDLLVTENFCLLTDSAAWLEKHKKYFALGLLYHYNNQDAAAV 506
Query 529 EIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMD---------------------FDSEKA 567
++++ + + DV + +L+ I D + +D +++
Sbjct 507 QLWVNIVNGDVQDST-RSDLYEYIVDFLTYCLDEELVWAYADWVLQKSEEVGVQVFTKRP 565
Query 568 VDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLY------- 620
+D ++ + ++ L+ P+ YL L + + YH LY
Sbjct 566 LDE--QQKNSFNPDDIINCLKKYPKALVKYLEHLVIDKRLQKEEYHTHLAVLYLEEVLLQ 623
Query 621 ----------AEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSAL 670
A + L L+ S + LE Q E+ L ++G AL
Sbjct 624 RASASGKGAEATETQAKLRRLLQKSDLYRVHFLLERLQGAGLPMESAILHGKLGEHEKAL 683
Query 671 KMIMEELHDVDKAIEF---AKEQDDG----ELWEDLILYSIDKPPFITG-------LLNN 716
+++ EL D A ++ E D +L+ L+ + P LLN
Sbjct 684 HILVHELQDFAAAEDYCLWCSEGRDPPHRQQLFHTLLAIYLHAGPTAHELAVAAVDLLNR 743
Query 717 IGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMH 776
T D ++ + + + L L+ ++D + + +++L
Sbjct 744 HATEFDAAQVLQMLPDTWSVQLLCPFLMGAMRDSIHARRTMQVALGLARSENLIYTYDKM 803
Query 777 RTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAA 832
+ + + + ++ +C+ C +P + + + H C N ++
Sbjct 804 KLKGSSIQLSDKKLCQICQNPFCEPVFVR------YPNGGLVHTHCAASRHTNPSS 853
>sp|O74925|PEP3_SCHPO Vacuolar membrane protein pep3 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=pep3
PE=3 SV=1
Length=900
Score = 71.3 bits (173), Expect = 3e-11, Method: Composition-based stats.
Identities = 86/530 (16%), Positives = 180/530 (34%), Gaps = 72/530 (14%)
Query 369 LLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAAL 428
LEK +E+AL A ++ + + Y L+E +Y+ AA + +
Sbjct 383 FLEKGDFEKALECANTAKV------RNTVLVGYAEFLMEHEEYERAAT----LYAETLKS 432
Query 429 WEYEVYKFKEIGQLKAISPYLPRGDPVLKPL-----------IYEMILHEFLESDYEGFA 477
E KF E+ Q + YL + K + E++L + D +
Sbjct 433 VEEVALKFIELNQKDVLRLYLWKKLRSYKSTMKIQKSLLVNWLLELMLAKLNSLDEKERL 492
Query 478 TLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHK 537
L E + + KD N+ LA Y ++ + + +
Sbjct 493 ELFPENVMQQRQQVQREFSTLLNQYKDEINREAAYNLANNYGKEEQLLQ-IATVMKDQSY 551
Query 538 DVFQLIHKHNL---FSSIKDKIVLLMDFDSEKAVDM--------LLDNEDKISIKKVVEE 586
+ + + N ++ + + A+ + + + + + ++
Sbjct 552 IMHYWVQRENYEKALETLNEGVSQETLIQHATALLTHRPNETVSIWERQTDLDVHALIPS 611
Query 587 LEDRPELQHV---------YLHKLFKRDHHKGQRYHEKQISLYAEYDRPN---LLPFLRD 634
L + HV YL + H +YA + N L+ ++
Sbjct 612 LLSYNQRSHVPVEENAAIRYLRYVTGVLGCVDPSIHNTLFCIYACHSSSNESYLMNYIEQ 671
Query 635 STH---CPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQD 691
+ ++ + +C Q N V +L M +++ + E D + A A +
Sbjct 672 QGNHPLYDMDLGIRLCLQFNCRRSAVKILVLMKLYSQGVELAL-EADDCELAATIANIPE 730
Query 692 DG-----ELWEDLILYSIDKPPFITGLLNNIGTHVDPIL--LIHRIKEGMEIPNLRDSLV 744
+ LW+ + Y K I L + L LI + E +++ +L D++
Sbjct 731 EDVVLKKTLWQTIAKYMFSKKSGIKETLRFLENSEVLQLPELIRLLPEDIKLDDLSDNVC 790
Query 745 KILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAA 804
L +I + + + + + ++++ C C P+ +
Sbjct 791 DELDHCMKRIEQLDFEIGQASEVAHEIQTNAENMRNRYIVLEPNESCWHCNQPLF----S 846
Query 805 KPFSVVVFHCRHMFHKECL-----PMPSMNSAAQFCNICSAKNRGPGSAI 849
+PF V+F C+H FH+ C+ + S + + C +C GP A+
Sbjct 847 EPF--VLFPCQHAFHRSCMLEKTYKLASEKNILKECQLC-----GPSYAV 889
>sp|Q3UR70|TGFA1_MOUSE Transforming growth factor-beta receptor-associated
protein 1 OS=Mus musculus OX=10090 GN=Tgfbrap1
PE=1 SV=1
Length=860
Score = 70.1 bits (170), Expect = 7e-11, Method: Composition-based stats.
Identities = 89/597 (15%), Positives = 199/597 (33%), Gaps = 107/597 (18%)
Query 328 QENECRDYHLEYSEG--ESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEIS 385
Q+ + + + E + + + V + + I LL ++ EEAL+ A+ +
Sbjct 277 QQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLANRRVEEALVLAKGA 336
Query 386 QKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAI 445
++NI + K + + + Q + L+ +E L ++
Sbjct 337 RRNIPKEKFQVMYRRIL-------QQAGFIQFAQLQFLEAKELFRSSQLDVRE---LISL 386
Query 446 SPYL-PRGDPVLK--PLIYEMI-LHEFLESDYEGFAT---LIREWPGDLYNNSVI----- 493
P+L P + P ++E L++ + D E A + + ++ + V
Sbjct 387 YPFLLPTSSSFTRSHPPLHEYADLNQLTQGDQEKMAKCKRFLMSYLNEIRSTEVANGYKE 446
Query 494 -VQAVRDHLKKDSQNKTLLK------------------------TLAELYTYDKNYGNAL 528
+ L ++ + +LL L LY Y+K +A+
Sbjct 447 DIDTALLKLYAEADHDSLLDLLVTENFCLLTDSAAWLEKHKKYFALGLLYHYNKQDASAV 506
Query 529 EIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMD---------------------FDSEKA 567
++++ + + D+ + +L+ I D + +D +++
Sbjct 507 QLWVNIVNGDIQDST-RSDLYEYIVDFLTYCLDQELVWTHADWLLQKSEEIGVQIFTKRP 565
Query 568 VDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLY------- 620
+D + + ++ L+ P+ YL L + + YH LY
Sbjct 566 LDE--QQQTSFNPDNIISSLKKYPKALVKYLEHLVIDRRLQKEEYHTHLAILYLEEVLRQ 623
Query 621 ----------AEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSAL 670
A + L L+ S + E Q E+ L ++G AL
Sbjct 624 RVSTGGKDVEATETQAKLRRLLQKSDLYRVHLLKEKVQGAGLPMESAILHGKLGEHEKAL 683
Query 671 KMIMEELHDVDKAIEFAKEQDDGE-------LWEDLILYSI-------DKPPFITGLLNN 716
+++ E+ D A ++ +G+ L+ L+ + D LLN+
Sbjct 684 HILVHEMGDFSAAEDYCLWSSEGQGAACRQRLFHTLLAMYLRAGPSAQDLTVAAVDLLNH 743
Query 717 IGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMH 776
D ++ + + + L L+ ++D + + +++L +
Sbjct 744 HAREFDVTQVLQLLPDTWSVQLLCPFLMGAMRDSIHARRTTQVALGLAKSENLIYMYDKM 803
Query 777 RTQMKGVLVDEENICESCLSPILPSDAAK--PFSVVVFHCRHMFHK-ECLPMPSMNS 830
+ + V + E +C+ C +P + +V HC H P P +
Sbjct 804 KLKGNAVRLSERELCQLCQNPFGEPVFVRYPNGGLVHTHCAASRHTAPSSPSPGTRT 860
>sp|F4I312|VPS3_ARATH Vacuolar sorting protein 3 OS=Arabidopsis
thaliana OX=3702 GN=VPS3 PE=1 SV=2
Length=984
Score = 70.1 bits (170), Expect = 7e-11, Method: Composition-based stats.
Identities = 48/231 (21%), Positives = 99/231 (43%), Gaps = 26/231 (11%)
Query 603 KRDHHKGQRYHEK---QISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYL 659
+ D G H+ ISL+ R L FL+ S E+ LE+ + E L
Sbjct 732 EADVPNGSEAHDSNVGSISLFEVDVRERLQAFLQSSDLYDPEEILELVEGSELWLEKAIL 791
Query 660 LSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSID----KPPFITG--- 712
R+G L+++ +L D A ++ E + + L+ +D K P
Sbjct 792 YRRIGKETLVLQILALKLEDCAAAEQYCVEIGRPDAFMQLLDMYLDPQNGKEPMFKAAVR 851
Query 713 LLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQ---DYNLQILLREGCKKILVADSL 769
LL+N G +DP+ ++ ++ M + D+++++L+ ++ Q + + L DS
Sbjct 852 LLHNHGESLDPLQVLDKLSPDMPLKLASDTILRMLRARVHHHRQGQIVHNISRALDVDSR 911
Query 770 SLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPF------SVVVFHC 814
+ + + + +++E++C+SC + + K F ++V + C
Sbjct 912 LARLE---ERSRHMQINDESLCDSCYARL----GTKLFAMYPDDTIVCYKC 955
>sp|A4IG72|TGFA1_DANRE Transforming growth factor-beta receptor-associated
protein 1 homolog OS=Danio rerio OX=7955 GN=tgfbrap1
PE=2 SV=1
Length=863
Score = 69.7 bits (169), Expect = 7e-11, Method: Composition-based stats.
Identities = 94/534 (18%), Positives = 182/534 (34%), Gaps = 95/534 (18%)
Query 348 IVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINH--- 404
+ S + V + + I LL + EEAL E +Q+NI + K + +
Sbjct 299 VASSKAVYMLVPLPLERQIQDLLASHRVEEALTLTEAAQRNIPKEKYQILHRRILQQAGF 358
Query 405 -------LVERGDY--------DIAARKCQKILGKNAALWEYE--VYKFKEIGQLKAISP 447
+E ++ +L +++ +++F ++ L
Sbjct 359 IQFGQLQFLEAKEHFRKGQLDVRELISLYPLLLPASSSFTRCHPPLHEFADLNHLTQGDQ 418
Query 448 YLPRGDPVLKPLIYEMILHEFLESDY-EGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQ 506
K + LHE SD GF + LY +++ D L ++
Sbjct 419 ---EKVQRFKRFLIS-YLHEVRSSDIANGFHEDVDTALLKLY-AETSHESLLDLLASENA 473
Query 507 -----NKTLLK------TLAELYTYDKNYGNALEIYLTLRHKDV---------------- 539
+ L+ L LY Y+ AL++++ + + D+
Sbjct 474 CLLADSAPWLEKHHKYYALGLLYHYNGQDAAALQMWVKIVNGDLQDSTRPDLFEYVVDFL 533
Query 540 -----FQLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQ 594
L+ +H ++ KD+ + + F + + +++ V+ L+ +
Sbjct 534 SFCSNLDLVWRHADWALQKDQKIGVQIFTKRPTSE---ERRGQLNADDVITYLQKHSQAL 590
Query 595 HVYLHKLFKRDHHKGQRYHEKQISLYAEY-----------------DRPNLLPFLRDSTH 637
+YL L + ++YH LYAE R L L++S
Sbjct 591 LLYLEHLVLEKKLQKEKYHTHLAVLYAEKVLGLISRPSTSEEQLSAARQKLQRLLKESNL 650
Query 638 CPLEKAL-EICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAK----EQDD 692
++ L +I + E L ++ AL +++ +L D A E+ QD
Sbjct 651 YRVQLLLGKIQDSELLLLERATLHGKLEEHDKALHVLVHQLKDSSAAEEYCSWASASQDS 710
Query 693 G---ELWEDLILYSIDKPPFITG--------LLNNIGTHVDPILLIHRIKEGMEIPNLRD 741
L+ L+ +D P G LLN D + ++ + E +P LR
Sbjct 711 SYRQNLFHQLLSVYLD-PDVPGGAQTVAAVDLLNRHAEVFDAVRVLKLLPEDWSLPLLRP 769
Query 742 SLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCL 795
L ++ + + A +L LL + + VLV E+ C+ C
Sbjct 770 FLCGAMRATVHARCTSQVALGLARAQNLQLLHDRLKYRGGPVLVSEKKGCQLCH 823
>sp|Q9VEA2|VPS39_DROME Vacuolar protein sorting-associated protein
39 homolog OS=Drosophila melanogaster OX=7227 GN=Vps39
PE=1 SV=1
Length=876
Score = 68.6 bits (166), Expect = 2e-10, Method: Composition-based stats.
Identities = 74/400 (19%), Positives = 140/400 (35%), Gaps = 49/400 (12%)
Query 448 YLPRGDPVLKPL--IYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDS 505
+L + LK I E+I+ ++ ++ L+RE + + +L++
Sbjct 490 HLEESEKTLKKHNKISELIILYQMKGKHKEALKLLREQASIEGSVLQGRKRTIRYLQELG 549
Query 506 QNK-TLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDS 564
+ L+ A+ D L I+ +LI +L + K++
Sbjct 550 GDHLPLIFEFADWVLNDN-PEEGLTIFTD-------ELIEVESL---PRAKVLDFFISKH 598
Query 565 EKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYD 624
+ V L++ V+ E +D L H L K ++ + EK +
Sbjct 599 KALVIPYLEH--------VITEWKDGNTLLHNVLLKQYREKVQRLLAQQEKGEEVPELIP 650
Query 625 -RPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKA 683
R L L +S ++ LE +EE +L R+ + L + + L DV KA
Sbjct 651 MRAKLYKMLEESNDYSPDRLLEEFPTNILLEERALILGRLKKHDNVLSIYIHVLGDVAKA 710
Query 684 IEFAKEQ--DDGELWEDLILYSIDKP-----------PFITG--------LLNNIGTHVD 722
+A+ +D ++ LI + P P + +LN T +D
Sbjct 711 TAYAEAHYKEDKHIFHTLIKCILIPPTQPLYDGVPLHPDFSQVNREVALEILNTHATRID 770
Query 723 PILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKG 782
P + + + M +P L L K ++ + L A+S L + +
Sbjct 771 PFEIFEHLPDDMPMPQLEKYLEKSIRKMMADKHEMQMMCGFLEAESTRLENALEEQRNIS 830
Query 783 VLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKEC 822
++E ++C C A V + H+ H C
Sbjct 831 FELNESSVCSECKKRFQTQSA-----FVRYPNGHIVHLSC 865
>sp|P27801|PEP3_YEAST Vacuolar membrane protein PEP3 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PEP3
PE=1 SV=1
Length=918
Score = 64.0 bits (154), Expect = 5e-09, Method: Composition-based stats.
Identities = 80/516 (16%), Positives = 169/516 (33%), Gaps = 92/516 (18%)
Query 374 KYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKN-------- 425
+ A +Q + G +N ++ DY+ K L
Sbjct 377 LFHTAKDFHSAAQTLGSMKDLSHFGEIALN-FLQIKDYNDLNVILIKQLDNVPWKSTQVV 435
Query 426 AALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPG 485
+ W + + QL I + P + + L+ +
Sbjct 436 LSSWIIWNF----MKQLNDIELKINTTKPASTDEDNLLNWNLNLKEKSNELTKFLESHLE 491
Query 486 DLYNNSVIVQAVRDHLKKDS-----QNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF 540
L +N + Q + +++ +K L + N+ +L+I LT+ + D
Sbjct 492 KL-DNETVYQIMSKQNRQNELLIFASLINDMKFLLSFWIDQGNWYESLKILLTINNHD-- 548
Query 541 QLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEEL------------- 587
L++K++L ++ +S +A + K++ +
Sbjct 549 -LVYKYSL----------ILLLNSPEATVSTWMKIKDLDPNKLIPTILKFFTNWQNNSKL 597
Query 588 -----EDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPN-------LLPFLRDS 635
E YL + I D N ++ F++ +
Sbjct 598 ITNISEYPENYSLTYLKWCVREVPKMCNPIVYNSILYMMITDPRNDMILENDIIKFMKSN 657
Query 636 TH-CPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEE--------LHDVDKAIEF 686
+ L L + + + +++LL+R+ A+ + ++ + + + IE
Sbjct 658 ENKYDLNFQLRLSLKFKKTKTSIFLLTRLNLFEDAIDLALKNNLIDDCKVIVNDEILIED 717
Query 687 AKEQDDGELWEDLILY------SIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLR 740
K + LW + + ID I +LN+ + L+ E I NL+
Sbjct 718 YKLR--KRLWLKIAKHLLLSMKDIDIKQLIRTILNDSNEILTIKDLLPFFNEYTTIANLK 775
Query 741 DSLVKILQDYN------LQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESC 794
+ L+K L+++N + ++ K+ + +S +++R G C+ C
Sbjct 776 EELIKFLENHNMKMNEISEDIINSKNLKVEINTEISKFNEIYRILEPGKS------CDEC 829
Query 795 LSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNS 830
+ K F +VF C H FH C+ +NS
Sbjct 830 GKFL----QIKKF--IVFPCGHCFHWNCIIRVILNS 859
>sp|Q9SJ40|VPS11_ARATH Vacuolar protein-sorting-associated protein
11 homolog OS=Arabidopsis thaliana OX=3702 GN=VPS11 PE=1
SV=1
Length=932
Score = 62.8 bits (151), Expect = 1e-08, Method: Composition-based stats.
Identities = 103/597 (17%), Positives = 211/597 (35%), Gaps = 114/597 (19%)
Query 348 IVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVE 407
I + + ++ E+D + +D L +K Y A+ + + ++ Y +HL
Sbjct 317 IKADKSLLCITEKDMESKLDMLFKKNLYTVAINLVQSQHADAAAT--ANVMRKYGDHLYG 374
Query 408 RGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPR-GDPVLKPLIYEMILH 466
+ D+D A Q I + + KF + ++ ++ YL + + L + +L
Sbjct 375 KQDFDEA--MLQYINTIGYLEPSFVIQKFLDAQRIYNLTNYLEKLHEKGLASKDHTTLLL 432
Query 467 EFLES--DYEGFATLIREWPGDLYNNSVIVQAVR----DHLKKDSQNKTLLKTLAELYTY 520
D E T IR+ G + A+R + + + E Y
Sbjct 433 NCYTKLKDVEKLNTFIRKEDGIGELKFDVETAIRVCRAANYHEHAMYVAKKAGKHEWYLK 492
Query 521 D-----KNYGNALEIYLTLRHKDVFQLIHKHN---LFSSIKDKIVLLMDFDSEKA----- 567
NY AL+ +L I ++ + K+ I +LM +E+
Sbjct 493 ILLEDLGNYDEALQYVSSLEPSQAGVTIEQYGKILIEHKPKETIDILMRLCTEQGIPNGV 552
Query 568 -----------VDMLLDNEDKIS--IKKVVEELEDRP---ELQHVYLHKLFKRDHH-KGQ 610
+ + + + + +++ E ++D P E+ + L RD +
Sbjct 553 FLSMLPSPVDFITVFVQHPHSLMHFLERYAEIVQDSPAQAEINNTLLELYLSRDLNFPSI 612
Query 611 RYHEKQIS----------LYAEYDR---------------------------PNLLPFLR 633
E + ++ D P
Sbjct 613 SLSENGLDKDLIDHSVAAAVSKADPEKKTNADSKDAMEKDCTERQQKGLELLKMAWPSDL 672
Query 634 DSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDG 693
+ ++ A+ +C+ +F + +YL +M + + M+ HD + I K D
Sbjct 673 EQPLYDVDLAVILCEMNSFKDGLLYLYEKMKFYKEVIACYMQN-HDHEGLIACCKRLGDS 731
Query 694 ------ELWEDLILYSIDKPPFITGLLNNIGTHVD------PILLIHRIKEGMEIPNLRD 741
LW DL+ Y + T + + T+++ PI+++ + + P L
Sbjct 732 SKGGDPSLWADLLKYFGEIGEDCTKEVKEVLTYIERDDILPPIIVLQTLAKN---PCLTL 788
Query 742 SLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPS 801
S++K DY + L +E KI+ D + ++ K + + E++ + L
Sbjct 789 SVIK---DYIARKLEQES--KIIEEDRR--AVEKYQETTKNMRKEIEDLRTNARIFQLSK 841
Query 802 DAAKPFSVVV----FHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGPGSAILEMKK 854
A F++ + F C H FH+ CL + C C+ + R +++EMK+
Sbjct 842 CTACTFTLDIPAVHFMCMHSFHQRCL-----GDNEKECPECAPEYR----SVMEMKR 889
>sp|A7MB11|TGFA1_BOVIN Transforming growth factor-beta receptor-associated
protein 1 OS=Bos taurus OX=9913 GN=TGFBRAP1 PE=2
SV=1
Length=859
Score = 60.9 bits (146), Expect = 5e-08, Method: Composition-based stats.
Identities = 88/589 (15%), Positives = 199/589 (34%), Gaps = 111/589 (19%)
Query 328 QENECRDYHLEYSEG--ESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEIS 385
Q+ + + + E + + + V + + I LL + EEAL+ A+ +
Sbjct 277 QQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKRIQDLLASHRVEEALVLAKGA 336
Query 386 QKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAI 445
++NI + K + L++ G A + K E+++ ++ + I
Sbjct 337 RRNIPKEKFQVMYRRI---LLQAGFIQFAQLQFLK---------AKELFRSGQLDVRELI 384
Query 446 SPY---LPRGDPVLK--PLIYEMI-LHEFLESDYEGFAT---LIREWPGDLYNNSVI--- 493
S Y LP + P ++E L++ + D + A + + ++ + V
Sbjct 385 SLYPLLLPTSSSFTRSHPPLHEFADLNQLTQGDQDKVAKCKRFLMSYLNEVRSTEVANGY 444
Query 494 ---VQAVRDHLKKDSQNKTLLK------------------------TLAELYTYDKNYGN 526
+ L ++ + +LL L LY Y+
Sbjct 445 KEDIDTALLKLYAEADHDSLLDLLVTENFCLLPDSAAWLEKHKKYFALGLLYHYNHQDAA 504
Query 527 ALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFD---------------------SE 565
A+++++++ + D+ + +L+ I D + D D ++
Sbjct 505 AVQLWVSIVNGDIQDST-RSDLYEYIVDFLTYSTDPDLVWRHADWVLQRSQEVGVQVFTK 563
Query 566 KAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEY-- 623
+ +D + + + ++ L+ P+ YL L + + YH LY +
Sbjct 564 RPLD---EQQSGFNPDDIISCLKKYPQALVKYLEHLVTERRLQKEEYHTHLAVLYLDEVL 620
Query 624 ---------------DRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRS 668
+ L L++S + ++ + E+ L ++
Sbjct 621 QQRPCTPDKDAEVTETQAKLRRLLQESDLYRVHFLMDRTRGAGLPLESAILHGKLEQHEE 680
Query 669 ALKMIMEELHDVDKAIEFA------KEQDDGELWEDLILYSIDKPPFIT--------GLL 714
AL +++ EL D A ++ ++ + L+L P LL
Sbjct 681 ALHILVHELADFPAAEDYCLWRSEGRDPPYRQRLFHLLLAVYLGPGPAAPARTVAAVDLL 740
Query 715 NNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKK 774
N D ++ + + LR L+ ++D + + +++L
Sbjct 741 NRHAVEFDAAQVLQLLPGTWSVQLLRPFLMGAMRDSIHARRTTQVAVGLARSENLIYKYD 800
Query 775 MHRTQMKGVLVDEENICESCLSPILPSDAAK--PFSVVVFHCRHMFHKE 821
+ + V + +E +C+ C +P L + +V HC H E
Sbjct 801 KMKLKGSSVRLSDEKLCQMCQNPFLEPVFVRYPNGGLVHTHCAASRHTE 849
>sp|Q07468|VAM6_YEAST Vacuolar morphogenesis protein 6 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=VAM6 PE=1 SV=1
Length=1049
Score = 58.6 bits (140), Expect = 2e-07, Method: Composition-based stats.
Identities = 50/295 (17%), Positives = 117/295 (40%), Gaps = 44/295 (15%)
Query 542 LIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKL 601
L+++HN SIK+ + + +DS+ + D + + +++ + +Q YL
Sbjct 714 LLNRHN--DSIKEILSSIFFYDSQACS-----SRDHLKVYGYIKKFDKLLAIQ--YLEFA 764
Query 602 FKRDHHKGQRYHEKQISLYAE--------------------YDRPNLLPFLRDSTHCPLE 641
+G + H I LY E Y+ +L L D+ +
Sbjct 765 ISTFRLEGNKLHTVLIKLYLENLDIPSTRIKLKSLLETTSVYEPRTILKLLNDAIESGSD 824
Query 642 KALEICQQRNFVEET-VYLLSRMGNSRSALKMIMEELHDVDKAIEFAKE--QDDGELWED 698
+ Q NFV+ ++ LS++ N + A+ ++++E+ D A + + Q D E+
Sbjct 825 QLPT--NQLNFVKYLKIFPLSKLENHKEAVHILLDEIDDYKAATSYCNDVYQSDSTKGEE 882
Query 699 LILYSIDK----------PPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQ 748
L+LY K I L + G+ ++ + + + + + ++ + ++L+
Sbjct 883 LLLYLYSKLVSIYDSNRNSKLILNFLQDHGSKLNSAEIYKNLPQDISLYDIGRVVSQLLK 942
Query 749 DYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDA 803
+ ++ K +L + ++ K++ ++ + + C C I
Sbjct 943 KHTSKMDETRLEKALLQVELVATTYKLNERMSSYGVLSDSHKCPICKKVISNFGT 997
>sp|Q54YP4|VPS11_DICDI Vacuolar protein sorting-associated protein
11 homolog OS=Dictyostelium discoideum OX=44689 GN=vps11
PE=3 SV=1
Length=952
Score = 58.2 bits (139), Expect = 3e-07, Method: Composition-based stats.
Identities = 49/295 (17%), Positives = 111/295 (38%), Gaps = 44/295 (15%)
Query 575 EDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYD---------- 624
+ K + ++ + + + +L + ++ +++ + + LY D
Sbjct 633 KQKSAPEEFIHIFVSQADWLVKFLEYMVQQGNNESSLIYNTLLELYLRDDVNQTDDERIK 692
Query 625 -RPNLLPFLRD-STHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIME---ELHD 679
+ FL + + + AL + Q N+ E +YL ++ I+E E +D
Sbjct 693 RKAKAYEFLTNPKSKFDQDHALILVQVHNWKEGVLYLYEKL----ELFNEIIEYHMENND 748
Query 680 VDKAIEFAKEQD--DGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIP 737
D I+ K D LW + + + + T++D LI + +
Sbjct 749 YDGLIKACKRYGVKDPNLWVRALSFFSTNKQDCQDEIIEVLTNIDKENLIPPLLVIQILS 808
Query 738 NLRDSLVKILQDY---NLQILLREGCKKILV-----ADSLSLLKKMHRTQMKGVLVDEEN 789
+++ + +++DY L ++ K ++ + +++ + + ++
Sbjct 809 QNKNTTLAVIKDYISRRLSQETQQIDKDYTQIRQYADETEKMRHEINELRTNSK-IFQQT 867
Query 790 ICESCLSPI-LPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNR 843
C +CL + LPS V F C+H FH+ CL + C C+ N+
Sbjct 868 KCIACLLALDLPS--------VHFLCQHSFHQRCL-----GENERECPSCAGANK 909
Score = 54.3 bits (129), Expect = 4e-06, Method: Composition-based stats.
Identities = 41/236 (17%), Positives = 101/236 (43%), Gaps = 19/236 (8%)
Query 503 KDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDF 562
++ +T L+TL + ++Y + + L + +++ D++ D+
Sbjct 358 EEKDTQTKLETLFKKHSYQ--------VAIDLAKSQHYDNSAIADVYREYGDRLYAKGDY 409
Query 563 DSEKAVDMLLDNEDKISIKKVVEELEDRPEL--QHVYLHKLFKRDHHKGQRYHEKQISLY 620
D A+ L ++ V+ + D + Y+ L +++ + ++ Y
Sbjct 410 DG--AITQYLCTIGQLEPSYVIRKFLDAQRIHNLTSYIQALHEKNLATAN-HTTLLLNCY 466
Query 621 AEY-DRPNLLPF-LRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELH 678
+ D L F + D+ +E A+++C+Q + + ++L S+ LK+++E+L+
Sbjct 467 TKLKDVKKLDHFIMTDNGTFDVETAIKVCRQGGYFDRALFLASKHSRHDWYLKILLEDLN 526
Query 679 DVDKAIEFAK----EQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRI 730
+ KA+++ + E+ D L + + P TG+L + T+ P+ +
Sbjct 527 EYRKALDYIQTLDWEEADKNLKKYGKQLVSEIPEETTGVLMKLCTNYQPVQAFDSL 582
>sp|P39702|VPS8_YEAST Vacuolar protein sorting-associated protein
8 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=VPS8 PE=1 SV=2
Length=1274
Score = 58.2 bits (139), Expect = 3e-07, Method: Composition-based stats.
Identities = 74/443 (17%), Positives = 139/443 (31%), Gaps = 104/443 (23%)
Query 495 QAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKD 554
++ + + K K L +Y + Y +AL + L + + ++ I
Sbjct 836 SRTTENFILELKEKNFNKVLFHIYKSENKYASALSLILETKDIEKEYNTDIVSITDYILK 895
Query 555 KIVLLMDFDSEKAVDMLLDNED----KISIKKVVEELED-------------RPELQHVY 597
K + K +++ N D +I I+K V D E Q Y
Sbjct 896 KCPP-GSLECGKVTEVIETNFDLLLSRIGIEKCVTIFSDFDYNLHQEILEVKNEETQQKY 954
Query 598 LHKLFKR---DHHKGQRYHEKQISLYAEYDRPN------------------LLPFLRDST 636
L KLF ++ +R I L +Y +L L +
Sbjct 955 LDKLFSTPNINNKVDKRLRNLHIELNCKYKSKREMILWLNGTVLSNAESLQILDLL--NQ 1012
Query 637 HCPLEKALEICQQRNFVEETV-----YLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQD 691
E A I ++ V ++ + ++ + ++E L +A +
Sbjct 1013 DSNFEAAAIIHERLESFNLAVRDLLSFIEQCLNEGKTNISTLLESLR---RAFDDCNSAG 1069
Query 692 DGE--LWEDLILYSI----DKPPF--ITGLLNNIGTHVDPILLIHRIKEG---------- 733
+ W LI + I P L N + L+ +
Sbjct 1070 TEKKSCWILLITFLITLYGKYPSHDERKDLCNKLLQEAFLGLVRSKSSSQKDSGGEFWEI 1129
Query 734 ------------MEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMK 781
M++ +L+ L+ + Y L+ L E +KI+ S L+++ + +
Sbjct 1130 MSSVLEHQDVILMKVQDLKQLLLNVFNTYKLERSLSELIQKIIEDSSQDLVQQYRKFLSE 1189
Query 782 GVLVDEENICESC----------------------LSPILPSDAAKPFSVVVFHCRHMFH 819
G + + CE C ++ D P +V+F C H FH
Sbjct 1190 GWSI-HTDDCEICGKKIWGAGLDPLLFLAWENVQRHQDMISVDLKTP--LVIFKCHHGFH 1246
Query 820 KECLPMPSMNSAAQFCNICSAKN 842
+ CL + C IC ++
Sbjct 1247 QTCLENLAQKPDEYSCLICQTES 1269
>sp|Q6P5M2|SKI8_DANRE Superkiller complex protein 8 OS=Danio rerio
OX=7955 GN=skic8 PE=2 SV=1
Length=305
Score = 56.6 bits (135), Expect = 3e-07, Method: Composition-based stats.
Identities = 48/234 (21%), Positives = 87/234 (37%), Gaps = 29/234 (12%)
Query 21 EEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQ-GNITQK 79
+E+ E + L+ +L I Q A + + D + L D++ G +
Sbjct 51 DEKLELQWTLEGHQLGVVSVNISQNGAIAASSSLDAH---------IRLWDLETGKQIKS 101
Query 80 FDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE--TFDCPIKIIAVHPHFV 137
D PV ++ +++ S GKV +FG+ SG++ H T I IA P
Sbjct 102 MDAGPVDAWTVAFSPDSKYIATGSHLGKVNIFGVESGKKEHSLDTRGKFILSIAYSPD-- 159
Query 138 RSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEG---NIRSVKWRGH--LIAWANNMG- 191
K +G ++ + + +LH EG IRS+ + L+ A++ G
Sbjct 160 ---GKYLASGAIDGII---NIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGY 213
Query 192 VKIFDIISKQRITNVPRDDISLRPDMYPC---SLCWKDNVTLIIGWGTSVKVCS 242
+KI+D+ + + + + I W TS + C
Sbjct 214 IKIYDVQHANLAGTLSGHGSWVLSVAFSPDDTHFVSSSSDKSIKVWDTSSRSCV 267
>sp|B7FNU7|LIS1_PHATC Lissencephaly-1 homolog OS=Phaeodactylum
tricornutum (strain CCAP 1055/1) OX=556484 GN=PHATRDRAFT_17300
PE=3 SV=1
Length=439
Score = 55.9 bits (133), Expect = 9e-07, Method: Composition-based stats.
Identities = 31/200 (16%), Positives = 72/200 (36%), Gaps = 12/200 (6%)
Query 34 RLSNGVTEILQKDAASCMTVHDKFLAL--GTHYGKVYLLDVQ-GNITQKFDVSPVKINQI 90
RL T +C+ VH F + G+ G V + D + G + +N +
Sbjct 118 RLPCQHTLQGHSSVVTCVRVHPVFTVVVSGSEDGSVKVWDHESGEYIRTLKGHTNTVNGL 177
Query 91 SLDESGEHMGVCSEDGKVQV--FGLYSGEEFHETFDCPIKIIAVHPH----FVRSSCKQF 144
+ +G H+ CS D +++ F Y+ + D I + P + CK+
Sbjct 178 AFTPTGSHLASCSTDLSIKLWDFQTYACIKTLRGHDHTISSVVFLPFGGDLLTTTKCKRL 237
Query 145 VTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWA---NNMGVKIFDIISKQ 201
++ + + + +H+ +R++ R WA N+ + +++ +
Sbjct 238 LSASRDCTVKVWDLETGFCDQTIHDHNDWVRTLATRADGSVWASAGNDTVIYVYEQDRMK 297
Query 202 RITNVPRDDISLRPDMYPCS 221
+ + + + +
Sbjct 298 KAVELRGHEQVVESIAFLTQ 317
>sp|Q10161|CLH_SCHPO Probable clathrin heavy chain OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=chc1
PE=1 SV=1
Length=1666
Score = 55.1 bits (131), Expect = 3e-06, Method: Composition-based stats.
Identities = 53/376 (14%), Positives = 144/376 (38%), Gaps = 30/376 (8%)
Query 451 RGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTL 510
DP + +Y+ I L + + + R ++YN + + + L
Sbjct 719 TEDPEV---VYKYIQAACLMNQFTEVERICR--DNNVYNPEKVKNLL--------KEAKL 765
Query 511 LKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKH--NLFSSIKDKIV-LLMDFDSEKA 567
L + D+ Y ++ L ++FQ I + + S ++V L+D D ++
Sbjct 766 ADQLPLILVCDR-YDFVNDLVFYLFRNNMFQFIEIYVQRINPSKTPQVVGALLDIDCDEE 824
Query 568 V--DMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQR-YHEKQISLYAEYD 624
+ ++L+ ++ + ++VEE+E R L+ + + R ++ +Y + +
Sbjct 825 LVQNLLMSVVGQVPVDELVEEVERRNRLKLLLPYLESLLQSGSQDRAIYDALAKIYIDSN 884
Query 625 RPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAI 684
+ FL+++ + C++R+ ++ G + + + + E +
Sbjct 885 NNPEV-FLKENNFYDTLTVGKYCEKRDPY--LAFIAYEKGGNDTEIINLCNENSMFKQLA 941
Query 685 EFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHV---DPILLIHRIKEGMEIPN-LR 740
+ ++ D LW +++ S + P + ++ + + ++ + +++P+ L
Sbjct 942 RYLLKRSDSNLWSEVLQDSAYRRPLLDQVIATAVPESSDPEAVSIVVKALMEVDLPSQLI 1001
Query 741 DSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILP 800
+ L KI+ + + + + ++ K +D+ ++ E I
Sbjct 1002 ELLEKIVLQPSSFSENANLQNLLFLTAIKADKSRVMEYIDK---LDKYDVDEIAEIAIEN 1058
Query 801 SDAAKPFSVVVFHCRH 816
+ F + H +H
Sbjct 1059 GLYEEAFRIYKIHNKH 1074
Score = 47.0 bits (110), Expect = 0.001, Method: Composition-based stats.
Identities = 15/83 (18%), Positives = 39/83 (47%), Gaps = 0/83 (0%)
Query 624 DRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKA 683
D+ ++ ++ +++ EI + EE + A+K+++E++ +D+A
Sbjct 1032 DKSRVMEYIDKLDKYDVDEIAEIAIENGLYEEAFRIYKIHNKHEQAMKVLVEDIVSLDRA 1091
Query 684 IEFAKEQDDGELWEDLILYSIDK 706
++A+ + E+W L +D
Sbjct 1092 QDYAETVEQPEVWSRLAKAQLDG 1114
Score = 37.0 bits (84), Expect = 1.1, Method: Composition-based stats.
Identities = 30/191 (16%), Positives = 70/191 (37%), Gaps = 16/191 (8%)
Query 610 QRYHEKQISLYAEYDRPNLLPFLRDS-THCPLEKALEICQQRNFVEETVYLLSRMGNSRS 668
++ + LYA+Y ++ L+ + K + C Q + E V+L + +
Sbjct 1310 MAFYTELAILYAKYKPERMMEHLKLFWGRLNMAKVIRACDQMHLWNEAVFLYVHDQSYDN 1369
Query 669 ALKMIME--ELHDVDKAIEFAKEQDDGELWEDLILYSID-KPPFITGLLNNIGTHVDPIL 725
A ++ME E D + + EL+ + + ++ P +T LL + +D
Sbjct 1370 AAAVMMEQPEAFDHQSFKDIIVHVANLELYYRALNFYLEQHPMLLTDLLAALTPRIDHPR 1429
Query 726 LIHRIKEGMEIP----------NLR-DSLVKILQDYNLQILLREGCKKILVA-DSLSLLK 773
+I ++ P +L ++ D +++ + + + D +
Sbjct 1430 VIRIFEKSENTPLILNFMVAIQHLNIQAVNHAYNDLLIEMEDYQSLQDSIENYDHFDAIA 1489
Query 774 KMHRTQMKGVL 784
R + +L
Sbjct 1490 LARRLEKHSLL 1500
>sp|P34574|CLH_CAEEL Probable clathrin heavy chain 1 OS=Caenorhabditis
elegans OX=6239 GN=chc-1 PE=1 SV=1
Length=1681
Score = 54.3 bits (129), Expect = 5e-06, Method: Composition-based stats.
Identities = 80/545 (15%), Positives = 180/545 (33%), Gaps = 51/545 (9%)
Query 261 IVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSETCEEISSD 320
++ FE GL +V S E+ K + ++ ++ + + D
Sbjct 700 LIEMFENHKSYEGLFYFLGSIVNFSQDPEVHFKYIQAATRTGQIKEVERICRESQ--CYD 757
Query 321 ALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQ-DDHIDWLLEKKKYEE-- 377
A V+ F + + L +V D+V+ R+Q +I+ ++K
Sbjct 758 AERVKNFLKEAKLNDQLPLIIVCDRHNMV--HDLVLYLYRNQLQKYIEVFVQKVNAARLP 815
Query 378 ----ALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEV 433
AL+ + S+ IK+ I G I+ LVE + + L E
Sbjct 816 IVVGALLDVDCSEDAIKQLIINTRGKFDIDELVEEVEKRNRLKLLNHWLESKIQ--EGAT 873
Query 434 YKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVI 493
K Y+ + E L E D + + S
Sbjct 874 DAATHNAMAKI---YIDSNNNP------ERFLKENPYYDSKVVGKYCEKRDPHYAFLSYE 924
Query 494 VQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVF-QLIHKHNLFS-S 551
L +L K LA + R ++ Q++++ N+
Sbjct 925 RGQCDAELINVCNENSLFKNLA-------------RYLVKRRDFTLWEQVLNEENVHRRQ 971
Query 552 IKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQ- 610
+ D++V +++ D+ +++K + D P L K+ + +
Sbjct 972 LIDQVVQTALSETQDPEDI------SVTVKAFMAA--DLPNELIELLEKIVLDNSAFSEH 1023
Query 611 -RYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSA 669
I DR ++ +++ + I EE + + + SA
Sbjct 1024 RNLQNLLILTAMRADRTRVMEYIQKLDNYDAPDIANIAITSELYEEAFAIFKKFDVNSSA 1083
Query 670 LKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDP---ILL 726
+ +++E ++++D+A EFA++ + ++W L + + + +++ DP + +
Sbjct 1084 INVLIENVNNLDRAYEFAEKCNQSDVWASLAKAQLQQ-NLVKEAVDSFIKADDPGAYMEV 1142
Query 727 IHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVD 786
+++ + +L L + + E + L+ L++ +
Sbjct 1143 VNKCSQTEHWEDLVRYLQMARKKSRESYIETELVFALAKTGRLTELEEFIAGPNHAQIGQ 1202
Query 787 EENIC 791
+ C
Sbjct 1203 IGDRC 1207
>sp|Q10051|PRP19_CAEEL Pre-mRNA-processing factor 19 OS=Caenorhabditis
elegans OX=6239 GN=prp-19 PE=1 SV=2
Length=492
Score = 53.2 bits (126), Expect = 8e-06, Method: Composition-based stats.
Identities = 30/160 (19%), Positives = 63/160 (39%), Gaps = 18/160 (11%)
Query 47 AASCMTVHDKFLALGT--HYGKVYLLDVQGNITQK-FDVSPVKINQISLDESGEHMGVCS 103
A + H L GT V + D++ F + I+ E+G ++ S
Sbjct 340 AVHSIEFHPDGLIFGTGAADAVVKIWDLKNQTVAAAFPGHTAAVRSIAFSENGYYLATGS 399
Query 104 EDGKVQVFGLYSGEEFH---ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKL-LLFERSWM 159
EDG+V+++ L + PI ++ + GG+K+ +L +SW
Sbjct 400 EDGEVKLWDLRKLKNLKTFANEEKQPINSLSFD-----MTGTFLGIGGQKVQVLHVKSW- 453
Query 160 NRWKSAVLHEGEGNIRSVKWRGH---LIAWANNMGVKIFD 196
+ L + G + V++ + L+ + + +++F
Sbjct 454 --SEVVSLSDHSGPVTGVRFGENARSLVTCSLDKSLRVFS 491
Score = 46.6 bits (109), Expect = 8e-04, Method: Composition-based stats.
Identities = 37/167 (22%), Positives = 65/167 (39%), Gaps = 8/167 (5%)
Query 81 DVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSS 140
DV + ISL+ SG+++ S+D + SG+ + P IAVH
Sbjct 290 DVHQAPVTDISLNASGDYILSASDDSYWAFSDIRSGKSLCKVSVEPGSQIAVHSIEFHPD 349
Query 141 CKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKW--RGHLIAWANNMG-VKIFDI 197
F TG ++ N+ +A +RS+ + G+ +A + G VK++D+
Sbjct 350 GLIFGTGAADAVVKIWDLKNQTVAAAFPGHTAAVRSIAFSENGYYLATGSEDGEVKLWDL 409
Query 198 ISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVK 244
+ + ++ + L IG G V+V VK
Sbjct 410 RKLKNLKTFANEEKQPINSLS----FDMTGTFLGIG-GQKVQVLHVK 451
>sp|P74442|Y143_SYNY3 Uncharacterized WD repeat-containing protein
slr0143 OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803
/ Kazusa) OX=1111708 GN=slr0143 PE=4 SV=1
Length=1191
Score = 53.2 bits (126), Expect = 1e-05, Method: Composition-based stats.
Identities = 41/276 (15%), Positives = 90/276 (33%), Gaps = 52/276 (19%)
Query 17 DESEEEESEEEPKLKYERLSNGV--TEILQ--KDAASCMTV--HDKFLALGTHYGKVYLL 70
DE+ + P + +++ + + +L +D + + + H +A + G V+L
Sbjct 528 DETLSQYPATSPLVSLQQILSQIAEKNVLTGHRDGVTSVAISSHKNLIASASRDGTVHLW 587
Query 71 DVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFD---CPI 127
QG ++F I ++ +G+ +D V+++ L +T +
Sbjct 588 TPQGEFLREFTGHTGSIYRVDFSPNGKIFATAGQDQTVKIWDLDG--NLLQTLKGHQDSV 645
Query 128 KIIAVHPH---------------FVRSSCKQFVTGGKKLLLFERSWM---NRWKSAV--- 166
++ P + S K G + + + +V
Sbjct 646 YSVSFSPDGEILASTSRDRTVRLWHWRSGKTLAVLGGHTKSVDDAQFSPDGQTLVSVCRD 705
Query 167 ----LHEGEGNI-----------RSVKWR--GHLIAWANNMGVKIFDIISKQRITNVPRD 209
L + +GN+ V W G+L+A A + G + +
Sbjct 706 GQIRLWDLDGNLIRQFGLPEVAFFGVNWHPNGNLLAVAADDGTVRLWTPQGEIKATLSGH 765
Query 210 DISLRPDMYPC---SLCWKDNVTLIIGWGTSVKVCS 242
D + ++ L + +I W TS K+
Sbjct 766 DEFVTRVVFTPDGKQLFSSSSNGSVIHWSTSGKMLK 801
Score = 38.9 bits (89), Expect = 0.25, Method: Composition-based stats.
Identities = 18/96 (19%), Positives = 40/96 (42%), Gaps = 7/96 (7%)
Query 45 KDAASCMTVHDKF--LALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVC 102
K+ +++H LA G G + L + G + + ++NQ+ +G+++
Sbjct 997 KEPIRSVSLHPTLPQLAAGDEQGNLTLWNFDGTLIRSIVAHGDRLNQLQYSPNGKYLLSA 1056
Query 103 SEDGKVQVFGLYSGEEFHETFD---CPIKIIAVHPH 135
+G +++ + + T PI IA+ P
Sbjct 1057 GREGTAKIWSVEG--QLLHTLKSDPLPIDQIAISPD 1090
>sp|Q09600|VPS11_CAEEL Vacuolar protein sorting-associated protein
11 homolog OS=Caenorhabditis elegans OX=6239 GN=vps-11
PE=3 SV=2
Length=980
Score = 52.8 bits (125), Expect = 1e-05, Method: Composition-based stats.
Identities = 79/527 (15%), Positives = 194/527 (37%), Gaps = 73/527 (14%)
Query 359 ERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKC 418
E++ +D L++K ++ A++ A+ S+ K I Y N+L +GDY+ A ++
Sbjct 350 EKNLATKLDILVKKSMFDVAVLIAKNSRDGGDYLK--GIHAKYGNYLYGKGDYENAIQQY 407
Query 419 QKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYE--MILHEFLESDYEG- 475
++ +G Y + ++ + ++K + YL + ++ ++++ + + +
Sbjct 408 KETIG--MLEPSYVMKRYLDSSKIKELCIYLECLHDAKRDNEHQTKILMNAYAKQGEKKK 465
Query 476 ---FATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYL 532
F I + V ++ + L + L T + + +AL + +
Sbjct 466 LMEFVNKITDGTRVSRMRDVFEILLKWN---------YLAEASLLATKFQMHEDALNVII 516
Query 533 TLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPE 592
HK + + + I +++ + D+L+ D + + + E++++ +
Sbjct 517 HHMHKYTMGVTYISKM------PIESVIEMTGKFGRDLLIHARDDL-MHMLWEKIQENTD 569
Query 593 LQHVYLHKLFKRDHHKGQ------RYHEKQISLYAEYDRPNL---LPFLRDSTHCPLEK- 642
+ ++F Y E Q + + E+ P L + + ++ E+
Sbjct 570 AKKNNFMRIFDIFMGDMDASRVFLSYIENQTNEHDEFIIPILECQMRLFKVNSDWSQERL 629
Query 643 ---------------ALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFA 687
AL++ Q + ++L R S+ L M ++ D++ I
Sbjct 630 EEDIYRFINKKNEDAALQMAQLFDCTPVIEHILMRCHKSKE-LMMYHQKKRDLEAIIRLC 688
Query 688 ---KEQDDGELWEDLILYSIDKPPFITGLLN-------NIGTHVDPILLIHRIK--EGME 735
+++ LW D + + L+ + P++++ + E +
Sbjct 689 QSCSKEEKRRLWLDALSFIGKHATARDELIIIDLLKEIEASEQIHPLVVLELLAKNEHLT 748
Query 736 IPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCL 795
I ++RD ++ L+ + I K ++ L + + + C +C
Sbjct 749 ISSVRDYIIAWLRKQQIIIEEDRNTIK-ENNKAMGELDGTVESLKFNAQIMQVTKCSACD 807
Query 796 SPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKN 842
+P+ V F C+H +H C +M + C C
Sbjct 808 TPL-------QLPTVHFLCKHAYHVHCFESYNM-DGSDKCPACQTTR 846
>sp|Q1ZXS5|VPS39_CAEEL Vacuolar protein sorting-associated protein
39 homolog OS=Caenorhabditis elegans OX=6239 GN=vps-39
PE=1 SV=1
Length=926
Score = 52.0 bits (123), Expect = 2e-05, Method: Composition-based stats.
Identities = 68/414 (16%), Positives = 139/414 (34%), Gaps = 99/414 (24%)
Query 502 KKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHK--------DVFQLIHKH------N 547
KK +++ L++L LY K + AL++++ + D Q I ++ +
Sbjct 504 KKILESEGRLRSLFILYETRKKHEMALDLFIDQSSRPDADPFFDDAIQQIVEYLQSLGNS 563
Query 548 LFSSIKDKIVLLMDFDSEKAVDMLLDNEDK----ISIKKVVEELED-RPELQHVYLHKLF 602
I ++ + E V + +E + ++ K VVE L+ P+ YL +
Sbjct 564 NLPLILKYAKWVLAKNLEAGVQIFTSDETEMARNLNRKAVVEFLKSECPDALIPYLEHVI 623
Query 603 KRDHHKGQRYHEKQISLY---------------------------AEYD------RPNLL 629
+ +HE + Y + D R LL
Sbjct 624 FKWEEPSSYFHETLLEFYVARVNTLFKDYVHAFPDAFSDENITRAGDEDGELGLYRKRLL 683
Query 630 PFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAK- 688
FL S + L F EE +L R+ AL + + L +V A E+ +
Sbjct 684 KFLEVSHSYSPQTVLLQLAPHAFYEERALILGRLKQHEQALAIYVNTLKNVPAAEEYCRL 743
Query 689 -----EQDDGELWEDL--------------ILYSIDKPPF---------ITGLLNNIGTH 720
++ + +++ L I Y D PF + L+N+ ++
Sbjct 744 YYNAHDETNSQVYLMLFRTLVHPNQQQLHSIPYHADSTPFGSYRDDVSEASTLVNSTSSY 803
Query 721 -----------------VDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKI 763
+D + ++ + + + ++ ++Q Q R+ K +
Sbjct 804 QPDVNTAIKILAKHADKIDTVGALNMLPATTPLRVVFSAINAVIQTTGRQASTRKMEKSV 863
Query 764 LVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAK-PFSVVVFHCRH 816
L++ ++ Q ++V+ + C C I S + P + H
Sbjct 864 SQCAMSKKLERKNKAQSTKIIVNFSSECVVCEKKIAVSAFVRYPDGRLAHLYCH 917
>sp|Q0WLB5|CLAH2_ARATH Clathrin heavy chain 2 OS=Arabidopsis thaliana
OX=3702 GN=CHC2 PE=1 SV=1
Length=1703
Score = 51.6 bits (122), Expect = 3e-05, Method: Composition-based stats.
Identities = 35/252 (14%), Positives = 95/252 (38%), Gaps = 23/252 (9%)
Query 518 YTYDKNYGNALEIYLTLR-HKDVFQLIHKHNLFSSIKDKIVLLMDFDS-EKAVD------ 569
Y ++ A+ Y + +++ + +K++LF +V MD D +K +D
Sbjct 922 YCEKRDPTLAVVAYRRGQCDEELINVTNKNSLFKLQARYVVERMDGDLWDKVLDENNDYR 981
Query 570 -MLLDNE------DKISIKKVVEELE-----DRPELQHVYLHKLFKRDHHKGQRY--HEK 615
L+D + S ++V ++ D P L K+ ++ +
Sbjct 982 RQLIDQVVSTALPESKSPEQVSAAVKAFMTADLPHELIELLEKIVLQNSAFSGNFNLQNL 1041
Query 616 QISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIME 675
I + D ++ ++ + E+ + EE + + + A+ ++++
Sbjct 1042 LILTAIKADPSRVMDYINRLDNFDGPAVGEVAVEAQLYEEAFAIFKKFNLNVQAVNVLLD 1101
Query 676 ELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGME 735
+ +++A+EFA ++ +W + + + ++ + + D + I+ +
Sbjct 1102 NVRSIERAVEFAFRVEEDSVWSQVAKAQLRE-GLVSDAIESFIRADDATHFLEVIRVSED 1160
Query 736 IPNLRDSLVKIL 747
D + +L
Sbjct 1161 TDVYDDLVKYLL 1172
>sp|Q9P6N4|PEP5_SCHPO E3 ubiquitin-protein ligase pep5 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=vps11
PE=3 SV=1
Length=906
Score = 51.2 bits (121), Expect = 4e-05, Method: Composition-based stats.
Identities = 37/249 (15%), Positives = 95/249 (38%), Gaps = 23/249 (9%)
Query 590 RPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQ 649
P + + LF+ + + + + +LL + + L I Q
Sbjct 662 SPNYKTLINTCLFEAYIRESFASSNVEKQEFWQEKSNSLLK--KVEKNVDLNAVFLISQI 719
Query 650 RNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQ--DDGELWEDLILYSIDKP 707
F + ++ + G + + ++ +D+++A++ + D EL+ ++
Sbjct 720 LGFDDGVRFVQGKSGQTLDIFRSFCQQ-NDIERALKMVRVHGPDQQELYIMMLNCFASLE 778
Query 708 P------FITGLLNNIGTH--VDPILLIHRIKEGMEI--PNLRDSLVKILQDYNLQILLR 757
I ++N I + + P L+ + + + I ++ DS+ +L +Y I +
Sbjct 779 NVDSWYQDINEIVNIIVSQRLISPTQLLDILGKSVNIKLEHISDSMQSVLDNYRESISKQ 838
Query 758 EGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHM 817
++ D + ++ + + +V +E+ C +C + +V F C H
Sbjct 839 NEAIEMGKRDIEEITSQLSILRTRAFVV-QESKCSTCGIDL-------ELPMVHFRCGHS 890
Query 818 FHKECLPMP 826
+H+ C+
Sbjct 891 YHQRCVEDE 899
>sp|Q0WNJ6|CLAH1_ARATH Clathrin heavy chain 1 OS=Arabidopsis thaliana
OX=3702 GN=CHC1 PE=1 SV=1
Length=1705
Score = 50.9 bits (120), Expect = 5e-05, Method: Composition-based stats.
Identities = 31/206 (15%), Positives = 78/206 (38%), Gaps = 22/206 (11%)
Query 518 YTYDKNYGNALEIYLTLR-HKDVFQLIHKHNLFSSIKDKIVLLMDFDS-EKAV------- 568
Y ++ A+ Y + +++ + +K++LF +V MD D EK +
Sbjct 922 YCEKRDPTLAVVAYRRGQCDEELINVTNKNSLFKLQARYVVERMDGDLWEKVLTEENEYR 981
Query 569 DMLLDNE------DKISIKKVVEELE-----DRPELQHVYLHKLFKRDHHKGQRY--HEK 615
L+D + S ++V ++ D P L K+ ++ +
Sbjct 982 RQLIDQVVSTALPESKSPEQVSAAVKAFMTADLPHELIELLEKIVLQNSAFSGNFNLQNL 1041
Query 616 QISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIME 675
I + D ++ ++ + E+ EE + + + A+ ++++
Sbjct 1042 LILTAIKADPSRVMDYINRLDNFDGPAVGEVAVDAQLYEEAFAIFKKFNLNVQAVNVLLD 1101
Query 676 ELHDVDKAIEFAKEQDDGELWEDLIL 701
+ +++A+EFA ++ +W +
Sbjct 1102 NVRSIERAVEFAFRVEEDAVWSQVAK 1127
>sp|P53675|CLH2_HUMAN Clathrin heavy chain 2 OS=Homo sapiens OX=9606
GN=CLTCL1 PE=1 SV=2
Length=1640
Score = 50.1 bits (118), Expect = 9e-05, Method: Composition-based stats.
Identities = 35/183 (19%), Positives = 70/183 (38%), Gaps = 6/183 (3%)
Query 570 MLLDNEDKISIKKVVEEL--EDRPELQHVYLHKLFKRDH--HKGQRYHEKQISLYAEYDR 625
L + D I V+ D P L K+ + + + I + DR
Sbjct 978 ALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADR 1037
Query 626 PNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIE 685
++ ++ + I EE + + + SA+++++E + ++D+A E
Sbjct 1038 TRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNASAIQVLIEHIGNLDRAYE 1097
Query 686 FAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVK 745
FA+ ++ +W L + K + +N+ DP + ++ N D LVK
Sbjct 1098 FAERCNEPAVWSQLAQAQLQK-DLVKEAINSYIRGDDPSSYLEVVQSASRSNNWED-LVK 1155
Query 746 ILQ 748
LQ
Sbjct 1156 FLQ 1158
>sp|G0SC29|NLE1_CHATD Ribosome assembly protein 4 OS=Chaetomium
thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) OX=759272
GN=CTHT_0055700 PE=1 SV=2
Length=517
Score = 49.7 bits (117), Expect = 9e-05, Method: Composition-based stats.
Identities = 31/166 (19%), Positives = 65/166 (39%), Gaps = 11/166 (7%)
Query 53 VHDKFLALGTHYGKVYLLDVQGNITQ-KFDVSPVKINQISLDESGEHMGVCSEDGKVQVF 111
V LA G+ + D + + +S G+++ CS D V+V+
Sbjct 157 VSSSRLATGSGDNTARIWDTDSGTPKFTLKGHTGWVLGVSWSPDGKYLATCSMDTTVRVW 216
Query 112 GLYSGEEFHETFD---CPIKIIAVHPHFV-RSSCKQFVTGGKKLLLFERSWMNR--WKSA 165
SG++ ++ F + +A P+ + R + + K + R W+
Sbjct 217 DPESGKQVNQEFRGHAKWVLALAWQPYHLWRDGTARLASASKDCTV--RIWLVNTGRTEH 274
Query 166 VLHEGEGNIRSVKWRGHLIAWA--NNMGVKIFDIISKQRITNVPRD 209
VL +G++ VKW G + + ++ V+++D + + N
Sbjct 275 VLSGHKGSVSCVKWGGTDLIYTGSHDRSVRVWDAVKGTLVHNFTAH 320
>sp|Q5FVN8|WSDU1_RAT WD repeat, SAM and U-box domain-containing
protein 1 OS=Rattus norvegicus OX=10116 GN=Wdsub1 PE=2 SV=1
Length=476
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 28/182 (15%), Positives = 53/182 (29%), Gaps = 30/182 (16%)
Query 46 DAASCMTVHDKFLALGTHYGKVYLL---DVQGNITQKFDVSPVKINQISLDESGEHMGVC 102
D SC LA + + L D ++ S SG + C
Sbjct 13 DDVSCCAFSSTLLATCSLDKTIRLYSLSDFAELPHSPLKFHTYAVHCCSFSPSGHVLASC 72
Query 103 SEDGKVQVFGLYSGEEFH---ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLL-----F 154
S DG ++ +SG + P+++ P + ++L +
Sbjct 73 STDGTTVLWSAHSGHTLTVLEQPGGSPVRVCCFSPDSTYLASG---AADGSVVLWNAHSY 129
Query 155 ERSWMNRWKSAVLHE-----GEGNIRSVKWRGHLIAW-----------ANNMGVKIFDII 198
+ K + L G + + G L W A+++G+
Sbjct 130 KLYRCGSVKDSSLVACAFSPDGGLLVTGSSGGDLTVWDDRMRCLHSEKAHDLGITCCSFS 189
Query 199 SK 200
S+
Sbjct 190 SQ 191
>sp|Q9W328|LST8_DROME Protein LST8 homolog OS=Drosophila melanogaster
OX=7227 GN=Lst8 PE=1 SV=2
Length=313
Score = 48.5 bits (114), Expect = 1e-04, Method: Composition-based stats.
Identities = 40/198 (20%), Positives = 78/198 (39%), Gaps = 15/198 (8%)
Query 67 VYLLDVQGNITQ---KFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHET- 122
+ L D++ N T FD + ++ E G M ED V+++ + +
Sbjct 60 IRLYDLESNCTAPVINFDGVQKNVTRLGFQEDGNWMFTAGEDHHVRIWDMIAAPPHCSRI 119
Query 123 FDC--PIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIR--SVK 178
FDC P+ +HP+ V G + +F + ++ E + +I+ ++
Sbjct 120 FDCEAPVNAACLHPNQVE-----IAMGSQNGSVFLWDVKSERHERIVPEVDASIQDVAIS 174
Query 179 WRGHLIAWANNMG-VKIFDIIS-KQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGT 236
G +A ANN G I+ + S Q+++ + + Y + + L++
Sbjct 175 PDGRYLAAANNKGNCYIWSLTSQDQKMSTLRPNRKIPAHSRYILRCKFSPDSRLLLTTSG 234
Query 237 SVKVCSVKERHASEMRDL 254
VC K S+ R+L
Sbjct 235 DGTVCIWKTDDFSKWREL 252
>sp|Q6GMD2|SKI8_XENLA Superkiller complex protein 8 OS=Xenopus
laevis OX=8355 GN=skic8 PE=2 SV=1
Length=305
Score = 48.2 bits (113), Expect = 2e-04, Method: Composition-based stats.
Identities = 34/140 (24%), Positives = 62/140 (44%), Gaps = 17/140 (12%)
Query 67 VYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE--TF 123
+ L D++ G + D PV ++ +H+ S GKV +FG+ +G++ + T
Sbjct 88 IRLWDLESGKQIRSIDAGPVDAWSVAFSPDSQHLATGSHVGKVNIFGVETGKKEYSLDTR 147
Query 124 DCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEG---NIRSVKWR 180
I IA P K +G ++ + + +LH EG IRS+ +
Sbjct 148 GKFILSIAYSPD-----GKYLASGAIDGII---NIFDIATGKLLHTLEGHAMPIRSLTFS 199
Query 181 GH--LIAWANNMG-VKIFDI 197
L+ A++ G +KI+D+
Sbjct 200 TDSQLLVTASDDGYIKIYDV 219
>sp|B4N984|WDR55_DROWI WD repeat-containing protein 55 homolog
OS=Drosophila willistoni OX=7260 GN=GK12179 PE=3 SV=1
Length=504
Score = 48.2 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 35/209 (17%), Positives = 79/209 (38%), Gaps = 28/209 (13%)
Query 39 VTEILQKDAASCMTVHDK--FLALGTHYGKVYLLDV---QGNITQKFDVSPVKINQISLD 93
EI +D + + H + +AL T G V+L + + + + +V +
Sbjct 154 PPEIKLEDFITDICFHPERHIIALATIIGDVHLYEYSNEENKLLKTIEVHAKACRDVEFT 213
Query 94 ESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRS----SCKQFVTGGK 149
E G + CS+D V + + + E+ + ++ H + + F +G
Sbjct 214 EDGRSLITCSKDKSVMITDMET-EKLKKLYE------TAHDDAINKLLVLDERLFASGDD 266
Query 150 KLLLFERSWMNRWKSAV--LHEGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRIT 204
+ + W R K ++ L E E + + L+A + + + F+I +++
Sbjct 267 SGTV--KLWDFRTKDSIFELKEIEDQVTQMITNDQKKLLLATSADGYLTTFNIGARKLYV 324
Query 205 NVPRDDISLRPDMYPCSLCWKDNVTLIIG 233
+ + C ++ N L++G
Sbjct 325 QSEPYE-----EELNCMGIYRGNSKLVVG 348
>sp|Q2RBN7|CLH1_ORYSJ Clathrin heavy chain 1 OS=Oryza sativa subsp.
japonica OX=39947 GN=Os11g0104900 PE=3 SV=1
Length=1708
Score = 48.9 bits (115), Expect = 3e-04, Method: Composition-based stats.
Identities = 39/252 (15%), Positives = 93/252 (37%), Gaps = 24/252 (10%)
Query 518 YTYDKNYGNALEIYLTLR-HKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAV-------- 568
Y ++ A+ Y + ++ + +K++LF +V MD D V
Sbjct 922 YCEKRDPTLAVVAYRRGQCDDELINVTNKNSLFKLQARYVVERMDGDLWDKVLQPENEYR 981
Query 569 DMLLDNE------DKISIKKVVEELE-----DRPELQHVYLHKLFKRDHHKGQRY--HEK 615
L+D + S ++V ++ D P L K+ ++ +
Sbjct 982 RQLIDQVVSTALPESKSPEQVSAAVKAFMTADLPHELIELLEKIVLQNSAFSGNFNLQNL 1041
Query 616 QISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIME 675
I + D ++ ++ + E+ + EE + + + A+ ++++
Sbjct 1042 LILTAIKADPSRVMDYVNRLDNFDGPAVGEVAVEAQLFEEAFAIFKKFNLNVQAVNVLLD 1101
Query 676 ELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGME 735
+ +++A EFA ++ +W + + + ++ + + D + I+ E
Sbjct 1102 NIRSIERAEEFAFRVEEDAVWSQVAKAQLRE-GLVSEAIESFIRADDATHFLDVIRAAEE 1160
Query 736 IPNLRDSLVKIL 747
N+ D LVK L
Sbjct 1161 -ANVYDDLVKYL 1171
>sp|Q2QYW2|CLH2_ORYSJ Clathrin heavy chain 2 OS=Oryza sativa subsp.
japonica OX=39947 GN=Os12g0104800 PE=3 SV=1
Length=1708
Score = 48.5 bits (114), Expect = 3e-04, Method: Composition-based stats.
Identities = 39/252 (15%), Positives = 93/252 (37%), Gaps = 24/252 (10%)
Query 518 YTYDKNYGNALEIYLTLR-HKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAV-------- 568
Y ++ A+ Y + ++ + +K++LF +V MD D V
Sbjct 922 YCEKRDPTLAVVAYRRGQCDDELINVTNKNSLFKLQARYVVERMDGDLWDKVLQPENEYR 981
Query 569 DMLLDNE------DKISIKKVVEELE-----DRPELQHVYLHKLFKRDHHKGQRY--HEK 615
L+D + S ++V ++ D P L K+ ++ +
Sbjct 982 RQLIDQVVSTALPESKSPEQVSAAVKAFMTADLPHELIELLEKIVLQNSAFSGNFNLQNL 1041
Query 616 QISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIME 675
I + D ++ ++ + E+ + EE + + + A+ ++++
Sbjct 1042 LILTAIKADPSRVMDYVNRLDNFDGPAVGEVAVEAQLFEEAFAIFKKFNLNVQAVNVLLD 1101
Query 676 ELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGME 735
+ +++A EFA ++ +W + + + ++ + + D + I+ E
Sbjct 1102 NIRSIERAEEFAFRVEEDAVWSQVAKAQLRE-GLVSEAIESFIRADDATHFLDVIRAAEE 1160
Query 736 IPNLRDSLVKIL 747
N+ D LVK L
Sbjct 1161 -ANVYDDLVKYL 1171
>sp|D3Z7A5|DAW1_MOUSE Dynein assembly factor with WD repeat domains
1 OS=Mus musculus OX=10090 GN=Daw1 PE=2 SV=1
Length=415
Score = 48.2 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 32/185 (17%), Positives = 66/185 (36%), Gaps = 12/185 (6%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
+A G+ L D+Q G +I +S D SG+ + S D V V+
Sbjct 190 TVVATGSMDTTAKLWDIQNGEEVVTLTGHLAEIISLSFDTSGDRIITGSFDHTVVVWDAS 249
Query 115 SGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGG-KKLLLFERSWMNRWKSAVL-HEGEG 172
+G + H + C +TG K + + ++ + + H+ E
Sbjct 250 TGRKVHTLIG---HCAEISSALFNWDCSLILTGSMDKTCMLWDATSGKYVATLTGHDDEI 306
Query 173 NIRSVKWRGHLIAWANNMGV-KIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLI 231
+ G LIA A+ G ++++ +++ +T + + + + L+
Sbjct 307 LDSCFDYTGKLIATASADGTARVYNATTRKCVTKLEGHEGEISKISFNPQ-----GNRLL 361
Query 232 IGWGT 236
G
Sbjct 362 TGSSD 366
>sp|B4JSW8|WDR55_DROGR WD repeat-containing protein 55 homolog
OS=Drosophila grimshawi OX=7222 GN=GH23127 PE=3 SV=1
Length=503
Score = 48.2 bits (113), Expect = 3e-04, Method: Composition-based stats.
Identities = 43/233 (18%), Positives = 90/233 (39%), Gaps = 35/233 (15%)
Query 20 EEEESEEEPK-----LKYERLSNGVTEILQKDAASCMTVHDK--FLALGTHYGKVYLLDV 72
E++E++E + +K R + EI +D + + H + +AL T G V+L +
Sbjct 128 EDDETDETVRAMIAAIKKTR--SAPPEIKLEDFITDICFHPERDIIALATIIGDVHLYEY 185
Query 73 ---QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKI 129
+ + + +V + E G + CS+D V V + + E+ + ++
Sbjct 186 GNEENKLLRTIEVHAKACRDVEFTEDGRSLITCSKDKCVMVTDMET-EKLKKLYE----- 239
Query 130 IAVHPHFVRS----SCKQFVTGGKKLLLFERSWMNRWKSAV--LHEGEGNIRSVKWRGH- 182
H + + F TG + + W R K A+ L E E I +
Sbjct 240 -TAHDDAINKLFVLDERLFATGDDAGTV--KLWDFRTKDAIFELKEVEDQITQMLTNEQN 296
Query 183 --LIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIG 233
L+A + + + ++I +++ + + C ++ N L+ G
Sbjct 297 KLLLATSADGYLTTYNIGARKLYVQSEPYE-----EELSCMGIYRGNSKLVAG 344
>sp|Q5BK30|DAW1_RAT Dynein assembly factor with WD repeat domains
1 OS=Rattus norvegicus OX=10116 GN=Daw1 PE=2 SV=1
Length=415
Score = 47.8 bits (112), Expect = 3e-04, Method: Composition-based stats.
Identities = 34/185 (18%), Positives = 66/185 (36%), Gaps = 12/185 (6%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
+A G+ L D+Q G +I +S D SG+ + S D V V+
Sbjct 190 TVVATGSMDTTAKLWDIQSGEEVVTLTGHLAEIISLSFDTSGDRIITGSFDHTVVVWDAS 249
Query 115 SGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTG--GKKLLLFERSWMNRWKSAVLHEGEG 172
+G + H + C +TG K +L++ + + H+ E
Sbjct 250 TGRKVHTLIG---HCAEISSALFSWDCSLILTGSMDKTCMLWDATSGKCVATLTGHDDEI 306
Query 173 NIRSVKWRGHLIAWANNMGV-KIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLI 231
+ G LIA A+ G ++++ +++ IT + + + + L+
Sbjct 307 LDSCFDYTGKLIATASADGTARVYNATTRKCITKLEGHEGEISKISFNPQ-----GNRLL 361
Query 232 IGWGT 236
G
Sbjct 362 TGSSD 366
>sp|P29742|CLH_DROME Clathrin heavy chain OS=Drosophila melanogaster
OX=7227 GN=Chc PE=1 SV=1
Length=1678
Score = 48.2 bits (113), Expect = 4e-04, Method: Composition-based stats.
Identities = 29/211 (14%), Positives = 76/211 (36%), Gaps = 10/211 (5%)
Query 573 DNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQ--RYHEKQISLYAEYDRPNLLP 630
+ D IS+ D P L K+ I + DR ++
Sbjct 984 QDPDDISVTVKAFMTADLPNELIELLEKIILDSSVFSDHRNLQNLLILTAIKADRTRVMD 1043
Query 631 FLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQ 690
++ + I EE + + + SA+++++++++++++A EFA+
Sbjct 1044 YINRLENYDAPDIANIAISNQLYEEAFAIFKKFDVNTSAIQVLIDQVNNLERANEFAERC 1103
Query 691 DDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPN-------LRDSL 743
++ +W L + + + +++ DP + + ++ + L+ +
Sbjct 1104 NEPAVWSQLAKAQLQQ-GLVKEAIDSYIKADDPSAYVDVVDVASKVESWDDLVRYLQMAR 1162
Query 744 VKILQDYNLQILLREGCKKILVADSLSLLKK 774
K + Y L+ + +AD +
Sbjct 1163 KKARESYIESELIYAYARTGRLADLEEFISG 1193
>sp|P22137|CLH_YEAST Clathrin heavy chain OS=Saccharomyces cerevisiae
(strain ATCC 204508 / S288c) OX=559292 GN=CHC1 PE=1
SV=1
Length=1653
Score = 48.2 bits (113), Expect = 4e-04, Method: Composition-based stats.
Identities = 73/430 (17%), Positives = 152/430 (35%), Gaps = 52/430 (12%)
Query 371 EKKKYEEALM-----------AAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQ 419
+ + Y +AL AA + K IG A ++ L I
Sbjct 1080 KHEMYGKALKVLIEDIMSLDRAASYADKINTPELWSQIGTAQLDGL------RIPDAIES 1133
Query 420 KILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLK-PLIYEMILHEFLESDYEGFAT 478
I ++ + +E + ++ G+ + + P+L LK P I ++ + E
Sbjct 1134 YIKAEDPSNYENVIDIAEQAGKYEELIPFLLMARKTLKEPKIDGALILAYAE------LN 1187
Query 479 LIREWPGDLY-NNSVIVQAVRDHLKKDSQNKTLL---------KTLAELYTYDKNYGNAL 528
I E L +N + V D L ++ + K LA Y +Y A+
Sbjct 1188 KIHEIENLLAGSNVANLDHVGDKLFENKEYKAARLCYSAVSNYSKLASTLVYLGDYQAAV 1247
Query 529 EIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELE 588
+ + V++L++ + I+ K L +++++ + ++VE E
Sbjct 1248 DTARKASNIKVWKLVND----ACIEKKEFKLAQI---CGLNLIV---HAEELDELVERYE 1297
Query 589 DRPEL--QHVYLHKLFKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDS-THCPLEKALE 645
+ + E I LY++Y+ L+ + + K +
Sbjct 1298 SNGYFEELISLFEAGLGLERAHMGMFTELAI-LYSKYEPDKTFEHLKLFWSRINIPKVIR 1356
Query 646 ICQQRNFVEETVYLLSRMGNS-RSALKMIMEELHDVDKA--IEFAKEQDDGELWEDLILY 702
+Q + E V+L + +AL +I + D+D A E + + E++ I +
Sbjct 1357 AVEQAHLWSELVFLYAHYDEWDNAALTLIEKSTKDLDHAYFKEVVVKVSNLEIYYKAINF 1416
Query 703 SID-KPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCK 761
+ P + LL ++ +D + + +P ++ L+ +L N +
Sbjct 1417 YVKFHPSLLVDLLTSLTPRLDIPRTVKIFSKSDNLPLIKPFLINVLPKNNSVVNQAYHDL 1476
Query 762 KILVADSLSL 771
I D +L
Sbjct 1477 MIEEEDYKAL 1486
Score = 45.1 bits (105), Expect = 0.004, Method: Composition-based stats.
Identities = 15/84 (18%), Positives = 39/84 (46%), Gaps = 0/84 (0%)
Query 623 YDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDK 682
Y+ + ++ + ++ +C + + EE + + ALK+++E++ +D+
Sbjct 1041 YEPTKVSSYIEKLDNYDADEIAPLCIEHDLKEEAFEIYDKHEMYGKALKVLIEDIMSLDR 1100
Query 683 AIEFAKEQDDGELWEDLILYSIDK 706
A +A + + ELW + +D
Sbjct 1101 AASYADKINTPELWSQIGTAQLDG 1124
Score = 35.5 bits (80), Expect = 2.7, Method: Composition-based stats.
Identities = 58/320 (18%), Positives = 107/320 (33%), Gaps = 28/320 (9%)
Query 400 AYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLPRGDPVLKPL 459
+N A+ C L +A + V +++ G + + G + +
Sbjct 1260 KLVNDACIEKKEFKLAQICGLNLIVHAEELDELVERYESNGYFEELISLFEAGLGLERAH 1319
Query 460 I---YEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAE 516
+ E+ + + F L W N +++AV L L
Sbjct 1320 MGMFTELAILYSKYEPDKTFEHLKLFWSR--INIPKVIRAVE--------QAHLWSELVF 1369
Query 517 LYTYDKNYGNALEIYLTLRHKDV-----FQLIHKHNLFSSIKDKIVLLMDFDSEKAVDML 571
LY + + NA + KD+ +++ K + I + F VD+L
Sbjct 1370 LYAHYDEWDNAALTLIEKSTKDLDHAYFKEVVVKVSNLEIYYKAINFYVKFHPSLLVDLL 1429
Query 572 LDNEDKISIKKVVEELE--DRPELQHVYLHKLFKRDHHK-GQRYHEKQISLYAEYDRPNL 628
++ I + V+ D L +L + +++ Q YH+ I E D L
Sbjct 1430 TSLTPRLDIPRTVKIFSKSDNLPLIKPFLINVLPKNNSVVNQAYHDLMIE---EEDYKAL 1486
Query 629 LPFLRDSTHCP---LEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIE 685
+ L LE + F + L R +L I++E AIE
Sbjct 1487 QDAVDSYDKFDQLGLASRLESHKLIFFKKIGALLYRRNKKWAKSLS-ILKEEKLWKDAIE 1545
Query 686 FAKEQDDGELWEDLILYSID 705
A D ++ E L+ Y ++
Sbjct 1546 TAAISQDPKVVEALLTYFVE 1565
Score = 34.7 bits (78), Expect = 4.6, Method: Composition-based stats.
Identities = 55/318 (17%), Positives = 104/318 (33%), Gaps = 53/318 (17%)
Query 511 LKTLAELYTYDKNYGNALEIYLTLRH-KDVFQLIHKHNL-------------FSSIKDKI 556
T+A L Y ALE Y ++ K ++H + L +
Sbjct 616 KPTIASLSEKAGLYQRALENYTDIKDIKRC--VVHTNALPIDWLVGYFGKLNVEQSLACL 673
Query 557 VLLMDFDSEKAVDMLLDNE----DKISIKKVVEELED--RPELQHVYLHKLFKRDHHKGQ 610
LMD + + + ++ D I +++ ED E + YL L K
Sbjct 674 KALMDNNIQANIQTVVQVATKFSDLIGPSTLIKLFEDYNATEGLYYYLASLVNLTEDKDV 733
Query 611 RY----HEKQISLYAE----------YDRPNLLPFLRDSTHCPLEKALEICQQRNFVEET 656
Y ++ Y E YD + FL+D+ + +C + +FV E
Sbjct 734 VYKYIEAAAKMKQYREIERIVKDNNVYDPERVKNFLKDANLEDQLPLVIVCDRFDFVHEM 793
Query 657 VYLLSRMGNSR--SALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLL 714
+ L + N + + D + L+ + + P +
Sbjct 794 ILYLYKSQNLKFIETYVQQVNPSKTAQVVGALLDMDCDEAFIQSLLQSVLGQVP-----I 848
Query 715 NNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKK 774
N + T V+ + + +P L SL + +QD + + DS + +K
Sbjct 849 NELTTEVEKRNRLKIL-----LPFLEQSLSQGIQDQAVY-----NALAKIYIDSNNSPEK 898
Query 775 MHRTQMKGVLVDEENICE 792
+ + +D + CE
Sbjct 899 FLKENDQYDTLDVGHYCE 916
>sp|A0AUS0|WSDU1_DANRE WD repeat, SAM and U-box domain-containing
protein 1 OS=Danio rerio OX=7955 GN=wdsub1 PE=2 SV=1
Length=487
Score = 47.4 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 18/112 (16%), Positives = 36/112 (32%), Gaps = 11/112 (10%)
Query 45 KDAASCMTVHDKFLALGTHYGKVYLL---DVQGNITQKFDVSPVKINQISLDESGEHMGV 101
+D +C+ LA + + + D ++ G+++
Sbjct 12 RDDVNCVAFSGDLLATCSADKSICVYSSRDFSELPFSPLSGHGYGVHCCCFSACGQYLAS 71
Query 102 CSEDGKVQVFGLYSGE---EFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKK 150
CS D V+ + +GE P+++ A P V+GG
Sbjct 72 CSTDATTMVWSMDTGEIEAVLEHPGRSPVRVCAFSPD-----SSHLVSGGSD 118
>sp|B4KE10|WDR55_DROMO WD repeat-containing protein 55 homolog
OS=Drosophila mojavensis OX=7230 GN=GI10299 PE=3 SV=2
Length=506
Score = 47.4 bits (111), Expect = 5e-04, Method: Composition-based stats.
Identities = 43/249 (17%), Positives = 93/249 (37%), Gaps = 31/249 (12%)
Query 2 AEAEEQETGSLEESTDESEEEESEEEPKLKYERLS---NGVTEILQKDAASCMTVHDK-- 56
AE + + E++E++E + + + EI +D + + H +
Sbjct 112 AEPSGSGPSGSGDYSHLDEDDETDETVRAMIAAIKKPRSAPPEIRLEDFITDICFHPERD 171
Query 57 FLALGTHYGKVYLLDV---QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
+AL T G V+L + + + + +V + E G + CS+D V V +
Sbjct 172 IIALATIIGDVHLYEYGNEENKLLRSIEVHAKACRDVEFTEDGRSLITCSKDKCVMVTDM 231
Query 114 YSGEEFHETFDCPIKIIAVHPHFVRS----SCKQFVTGGKKLLLFERSWMNRWKSAV--L 167
+ E+ + ++ H + + F TG + + W R K A+ L
Sbjct 232 ET-EKLKKLYE------TAHDDAINKLHVLDERLFATGDDAGTV--KLWDFRTKDAIFEL 282
Query 168 HEGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCW 224
E E I + L+A + + + F+I +++ + + C +
Sbjct 283 KEVEDQITQMLTNEQNKLLLATSADGYLTTFNIGARKLYVQSEPYE-----EELNCMGIY 337
Query 225 KDNVTLIIG 233
+ + L++G
Sbjct 338 RGSSKLVVG 346
>sp|Q4V7A0|SKI8_RAT Superkiller complex protein 8 OS=Rattus norvegicus
OX=10116 GN=Skic8 PE=1 SV=1
Length=305
Score = 46.6 bits (109), Expect = 5e-04, Method: Composition-based stats.
Identities = 23/83 (28%), Positives = 38/83 (46%), Gaps = 3/83 (4%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
+ LA GTH GKV + V+ G D I I+ G+++ + DG + +F +
Sbjct 119 QHLATGTHMGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query 115 SGEEFH--ETFDCPIKIIAVHPH 135
+G+ H E PI+ + P
Sbjct 179 TGKLLHTLEGHAMPIRSLTFSPD 201
Score = 44.7 bits (104), Expect = 0.002, Method: Composition-based stats.
Identities = 34/140 (24%), Positives = 61/140 (44%), Gaps = 17/140 (12%)
Query 67 VYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE--TF 123
+ L D+ G + D PV ++ +H+ + GKV +FG+ SG++ + T
Sbjct 88 IRLWDLENGKQMKSIDAGPVDAWTLAFSPDSQHLATGTHMGKVNIFGVESGKKEYSLDTR 147
Query 124 DCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEG---NIRSVKWR 180
I IA P K +G ++ + + +LH EG IRS+ +
Sbjct 148 GKFILSIAYSPD-----GKYLASGAIDGII---NIFDIATGKLLHTLEGHAMPIRSLTFS 199
Query 181 GH--LIAWANNMG-VKIFDI 197
L+ A++ G +KI+D+
Sbjct 200 PDSQLLVTASDDGYIKIYDV 219
>sp|P11442|CLH1_RAT Clathrin heavy chain 1 OS=Rattus norvegicus
OX=10116 GN=Cltc PE=1 SV=3
Length=1675
Score = 47.8 bits (112), Expect = 6e-04, Method: Composition-based stats.
Identities = 23/137 (17%), Positives = 54/137 (39%), Gaps = 3/137 (2%)
Query 589 DRPELQHVYLHKLFKRDH--HKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEI 646
D P L K+ + + + I + DR ++ ++ + I
Sbjct 999 DLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANI 1058
Query 647 CQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDK 706
EE + + + SA+++++E + ++D+A EFA+ ++ +W L + K
Sbjct 1059 AISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQK 1118
Query 707 PPFITGLLNNIGTHVDP 723
+ +++ DP
Sbjct 1119 -GMVKEAIDSYIKADDP 1134
>sp|P49951|CLH1_BOVIN Clathrin heavy chain 1 OS=Bos taurus OX=9913
GN=CLTC PE=1 SV=1
Length=1675
Score = 47.8 bits (112), Expect = 6e-04, Method: Composition-based stats.
Identities = 23/137 (17%), Positives = 54/137 (39%), Gaps = 3/137 (2%)
Query 589 DRPELQHVYLHKLFKRDH--HKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEI 646
D P L K+ + + + I + DR ++ ++ + I
Sbjct 999 DLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANI 1058
Query 647 CQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDK 706
EE + + + SA+++++E + ++D+A EFA+ ++ +W L + K
Sbjct 1059 AISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQK 1118
Query 707 PPFITGLLNNIGTHVDP 723
+ +++ DP
Sbjct 1119 -GMVKEAIDSYIKADDP 1134
>sp|Q00610|CLH1_HUMAN Clathrin heavy chain 1 OS=Homo sapiens OX=9606
GN=CLTC PE=1 SV=5
Length=1675
Score = 47.8 bits (112), Expect = 6e-04, Method: Composition-based stats.
Identities = 23/137 (17%), Positives = 54/137 (39%), Gaps = 3/137 (2%)
Query 589 DRPELQHVYLHKLFKRDH--HKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEI 646
D P L K+ + + + I + DR ++ ++ + I
Sbjct 999 DLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANI 1058
Query 647 CQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDK 706
EE + + + SA+++++E + ++D+A EFA+ ++ +W L + K
Sbjct 1059 AISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQK 1118
Query 707 PPFITGLLNNIGTHVDP 723
+ +++ DP
Sbjct 1119 -GMVKEAIDSYIKADDP 1134
>sp|Q5ZJH5|SKI8_CHICK Superkiller complex protein 8 OS=Gallus
gallus OX=9031 GN=SKIC8 PE=2 SV=1
Length=305
Score = 46.6 bits (109), Expect = 6e-04, Method: Composition-based stats.
Identities = 23/83 (28%), Positives = 39/83 (47%), Gaps = 3/83 (4%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
+FLA G+H GKV + V+ G D I I+ G+++ + DG + +F +
Sbjct 119 QFLATGSHVGKVNIFGVETGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query 115 SGEEFH--ETFDCPIKIIAVHPH 135
+G+ H E PI+ + P
Sbjct 179 TGKLLHTLEGHAMPIRSLTFSPD 201
Score = 45.5 bits (106), Expect = 0.001, Method: Composition-based stats.
Identities = 33/140 (24%), Positives = 61/140 (44%), Gaps = 17/140 (12%)
Query 67 VYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE--TF 123
+ L D++ G + D PV ++ + + S GKV +FG+ +G++ + T
Sbjct 88 IRLWDLETGKQIKSIDAGPVDAWSLAFSPDSQFLATGSHVGKVNIFGVETGKKEYSLDTR 147
Query 124 DCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEG---NIRSVKWR 180
I IA P K +G ++ + + +LH EG IRS+ +
Sbjct 148 GKFILSIAYSPD-----GKYLASGAIDGII---NIFDIATGKLLHTLEGHAMPIRSLTFS 199
Query 181 GH--LIAWANNMG-VKIFDI 197
L+ A++ G +KI+D+
Sbjct 200 PDSQLLVTASDDGYIKIYDV 219
>sp|Q68FD5|CLH1_MOUSE Clathrin heavy chain 1 OS=Mus musculus OX=10090
GN=Cltc PE=1 SV=3
Length=1675
Score = 47.4 bits (111), Expect = 6e-04, Method: Composition-based stats.
Identities = 23/137 (17%), Positives = 54/137 (39%), Gaps = 3/137 (2%)
Query 589 DRPELQHVYLHKLFKRDH--HKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEI 646
D P L K+ + + + I + DR ++ ++ + I
Sbjct 999 DLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANI 1058
Query 647 CQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDK 706
EE + + + SA+++++E + ++D+A EFA+ ++ +W L + K
Sbjct 1059 AISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQK 1118
Query 707 PPFITGLLNNIGTHVDP 723
+ +++ DP
Sbjct 1119 -GMVKEAIDSYIKADDP 1134
>sp|Q9D0I6|WSDU1_MOUSE WD repeat, SAM and U-box domain-containing
protein 1 OS=Mus musculus OX=10090 GN=Wdsub1 PE=2 SV=1
Length=474
Score = 47.0 bits (110), Expect = 6e-04, Method: Composition-based stats.
Identities = 17/96 (18%), Positives = 29/96 (30%), Gaps = 6/96 (6%)
Query 46 DAASCMTVHDKFLALGTHYGKVYLL---DVQGNITQKFDVSPVKINQISLDESGEHMGVC 102
D SC LA + + L D ++ SG + C
Sbjct 13 DDVSCCAFSAALLATCSLDKTIRLYSLSDFAELPYSPLKFHTYAVHCCCFSPSGHVLASC 72
Query 103 SEDGKVQVFGLYSGEEFH---ETFDCPIKIIAVHPH 135
S DG ++ +SG + P+++ P
Sbjct 73 STDGTTVLWSSHSGHTLTVLEQPGGSPVRVCCFSPD 108
>sp|Q9GZS3|SKI8_HUMAN Superkiller complex protein 8 OS=Homo sapiens
OX=9606 GN=SKIC8 PE=1 SV=1
Length=305
Score = 46.2 bits (108), Expect = 7e-04, Method: Composition-based stats.
Identities = 23/83 (28%), Positives = 39/83 (47%), Gaps = 3/83 (4%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
++LA GTH GKV + V+ G D I I+ G+++ + DG + +F +
Sbjct 119 QYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query 115 SGEEFH--ETFDCPIKIIAVHPH 135
+G+ H E PI+ + P
Sbjct 179 TGKLLHTLEGHAMPIRSLTFSPD 201
Score = 45.9 bits (107), Expect = 9e-04, Method: Composition-based stats.
Identities = 33/140 (24%), Positives = 61/140 (44%), Gaps = 17/140 (12%)
Query 67 VYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE--TF 123
+ L D+ G + D PV ++ +++ + GKV +FG+ SG++ + T
Sbjct 88 IRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTR 147
Query 124 DCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEG---NIRSVKWR 180
I IA P K +G ++ + + +LH EG IRS+ +
Sbjct 148 GKFILSIAYSPD-----GKYLASGAIDGII---NIFDIATGKLLHTLEGHAMPIRSLTFS 199
Query 181 GH--LIAWANNMG-VKIFDI 197
L+ A++ G +KI+D+
Sbjct 200 PDSQLLVTASDDGYIKIYDV 219
>sp|Q8L5Y0|VPS39_ARATH Vacuolar sorting protein 39 OS=Arabidopsis
thaliana OX=3702 GN=VPS39 PE=1 SV=1
Length=1000
Score = 47.0 bits (110), Expect = 7e-04, Method: Composition-based stats.
Identities = 41/220 (19%), Positives = 80/220 (36%), Gaps = 46/220 (21%)
Query 513 TLAELYTYDKNYGNALEIYLTLRHK-----------DVF--QLIHKHNLFSSIKDKIVLL 559
L EL+ + + AL++ L + +F +LI ++ L + +L+
Sbjct 546 ALLELFKSNSMHHEALKLLNQLADESKTNQSQTDVTQIFSPELIIEY-LKPLCRTDPMLV 604
Query 560 MDFD-------SEKAVDMLLDNEDKISIKKVVEEL-EDRPELQHVYLHKLFKRDHHKG-- 609
+++ + +D+ L IS V L + P +Q YL + +
Sbjct 605 LEYSMLVLESCPTQTIDLFLSG--NISADLVNSYLKQHAPNMQGRYLELMMAMNDTAVSG 662
Query 610 -------QRYHEKQISLYA-----------EY--DRPNLLPFLRDSTHCPLEKALEICQQ 649
Q Y + + LYA ++ +R LL L + + L+ +
Sbjct 663 NLQNEMVQIYLSEVLDLYAAKSAQQKWDEKDHPPERKKLLSALESISGYSPQPLLKRLPR 722
Query 650 RNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKE 689
EE +L +M AL + + +LH D A+ +
Sbjct 723 DALYEERAVILGKMNQHELALSIYVHKLHAPDLALAYCDR 762
Score = 37.4 bits (85), Expect = 0.73, Method: Composition-based stats.
Identities = 38/260 (15%), Positives = 103/260 (40%), Gaps = 16/260 (6%)
Query 565 EKAVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFK--RDHHKGQRYHEKQISLYAE 622
E+AV + N+ ++++ V +L P+L Y ++++ G+ +++
Sbjct 728 ERAVILGKMNQHELALSIYVHKLH-APDLALAYCDRIYESVTYLPSGKPSSNIYLTVLQI 786
Query 623 Y--DRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDV 680
Y + + F + ++ + + + V L S+ RS + +E D+
Sbjct 787 YLNPKKSAKDFAKRIVALGSFESSDTTKMMDSV-----LSSKAKGGRSKKIVAIEGAEDM 841
Query 681 DKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPIL---LIHRIKEGMEIP 737
+ + + ++ + L D I+ +L+ + + I + + ++
Sbjct 842 RVGLSSSTDSGRSDVDTEEPLEEGDSTVMISEVLDLLSQRWERINGAQALKLLPRETKLH 901
Query 738 NLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSP 797
NL L +L++ + K + +++L + +++++ + V E++C C
Sbjct 902 NLLPFLAPLLRNSSEAHRNFSVIKSLRQSENLQVKEELYKHRKGVAQVTSESMCSLCNKK 961
Query 798 I---LPSDAAKPFSVVVFHC 814
I + + ++V F C
Sbjct 962 IGTSVFAVYPNGKTLVHFVC 981
>sp|Q9ERF3|SKI8_MOUSE Superkiller complex protein 8 OS=Mus musculus
OX=10090 GN=Skic8 PE=1 SV=1
Length=305
Score = 46.2 bits (108), Expect = 8e-04, Method: Composition-based stats.
Identities = 23/83 (28%), Positives = 39/83 (47%), Gaps = 3/83 (4%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
++LA GTH GKV + V+ G D I I+ G+++ + DG + +F +
Sbjct 119 QYLATGTHMGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query 115 SGEEFH--ETFDCPIKIIAVHPH 135
+G+ H E PI+ + P
Sbjct 179 TGKLLHTLEGHAMPIRSLTFSPD 201
Score = 45.5 bits (106), Expect = 0.001, Method: Composition-based stats.
Identities = 33/140 (24%), Positives = 61/140 (44%), Gaps = 17/140 (12%)
Query 67 VYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE--TF 123
+ L D+ G + D PV ++ +++ + GKV +FG+ SG++ + T
Sbjct 88 IRLWDLENGKQMKSIDAGPVDAWTLAFSPDSQYLATGTHMGKVNIFGVESGKKEYSLDTR 147
Query 124 DCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEG---NIRSVKWR 180
I IA P K +G ++ + + +LH EG IRS+ +
Sbjct 148 GKFILSIAYSPD-----GKYLASGAIDGII---NIFDIATGKLLHTLEGHAMPIRSLTFS 199
Query 181 GH--LIAWANNMG-VKIFDI 197
L+ A++ G +KI+D+
Sbjct 200 PDSQLLVTASDDGYIKIYDV 219
>sp|Q32LN7|SKI8_BOVIN Superkiller complex protein 8 OS=Bos taurus
OX=9913 GN=SKIC8 PE=2 SV=1
Length=305
Score = 46.2 bits (108), Expect = 8e-04, Method: Composition-based stats.
Identities = 23/83 (28%), Positives = 39/83 (47%), Gaps = 3/83 (4%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
++LA GTH GKV + V+ G D I I+ G+++ + DG + +F +
Sbjct 119 QYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIA 178
Query 115 SGEEFH--ETFDCPIKIIAVHPH 135
+G+ H E PI+ + P
Sbjct 179 TGKLLHTLEGHAMPIRSLTFSPD 201
Score = 45.9 bits (107), Expect = 0.001, Method: Composition-based stats.
Identities = 33/140 (24%), Positives = 61/140 (44%), Gaps = 17/140 (12%)
Query 67 VYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE--TF 123
+ L D+ G + D PV ++ +++ + GKV +FG+ SG++ + T
Sbjct 88 IRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTR 147
Query 124 DCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEG---NIRSVKWR 180
I IA P K +G ++ + + +LH EG IRS+ +
Sbjct 148 GKFILSIAYSPD-----GKYLASGAIDGII---NIFDIATGKLLHTLEGHAMPIRSLTFS 199
Query 181 GH--LIAWANNMG-VKIFDI 197
L+ A++ G +KI+D+
Sbjct 200 PDSQLLVTASDDGYIKIYDV 219
>sp|B3M1G0|WDR55_DROAN WD repeat-containing protein 55 homolog
OS=Drosophila ananassae OX=7217 GN=GF18399 PE=3 SV=1
Length=481
Score = 46.6 bits (109), Expect = 0.001, Method: Composition-based stats.
Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 8/113 (7%)
Query 11 SLEESTDESEEEESEEEPKLKYERLS---NGVTEILQKDAASCMTVHDK--FLALGTHYG 65
+E + D E+E++E + + + EI +D + ++ H + +AL T G
Sbjct 109 DVETNFDLDLEDETDETVRAIIAAIKKPRSAPPEIKLEDFVTDISFHPERNIIALATIIG 168
Query 66 KVYLLDV--QGN-ITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYS 115
V+L + +GN + + +V + E G ++ CS+D V V + +
Sbjct 169 DVHLYEYANEGNKLIRTIEVHSKACRDVEFTEDGRNLLTCSKDKCVMVTDMET 221
>sp|Q6PBD6|SKI8_XENTR Superkiller complex protein 8 OS=Xenopus
tropicalis OX=8364 GN=skic8 PE=2 SV=1
Length=305
Score = 45.5 bits (106), Expect = 0.001, Method: Composition-based stats.
Identities = 33/140 (24%), Positives = 62/140 (44%), Gaps = 17/140 (12%)
Query 67 VYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE--TF 123
+ L D++ G + D PV ++ +H+ S GKV +FG+ +G++ + T
Sbjct 88 IRLWDLESGKQIRAIDAGPVDAWSVAFSPDSQHLATGSHVGKVNIFGVETGKKEYSLDTR 147
Query 124 DCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEG---NIRSVKWR 180
I IA P K +G ++ + + +LH EG IRS+ +
Sbjct 148 GKFILSIAYSPD-----GKYLASGAIDGII---NIFDIATGKLLHTLEGHAMPIRSLTFS 199
Query 181 GH--LIAWANNMG-VKIFDI 197
L+ A++ G +KI+++
Sbjct 200 PDSQLLVTASDDGYIKIYEV 219
>sp|Q5ZMC3|WSDU1_CHICK WD repeat, SAM and U-box domain-containing
protein 1 OS=Gallus gallus OX=9031 GN=WDSUB1 PE=2 SV=2
Length=476
Score = 45.5 bits (106), Expect = 0.002, Method: Composition-based stats.
Identities = 29/186 (16%), Positives = 57/186 (31%), Gaps = 38/186 (20%)
Query 45 KDAASCMTVHDKFLALGTHYGKVYLL---DVQGNITQKFDVSPVKINQISLDESGEHMGV 101
D +C LA + + + D ++ SG +
Sbjct 12 SDDVNCCAFSSSCLATCSLDKTIRIYSLNDFTELPYSPLKGHTYAVHCCCFSPSGHTLAS 71
Query 102 CSEDGKVQVFGLYSGEEFH---ETFDCPIKIIAVHPHFVRSSCKQFVTG--GKKLLLFER 156
CS DG ++ G + P+++ P V+G ++L+
Sbjct 72 CSTDGATIIWDTSDGRMLAVLEQPTGSPVRVCRFSPE-----STYLVSGAADGSVVLWNV 126
Query 157 SWMNRWKSAVLHEGEGNIRSVKWR------------GHLIAW-----------ANNMGVK 193
M ++S + +G++ + + G L W A+++GV
Sbjct 127 HSMKFYRSGNVK--DGSLVACAFSPGGNFFVTGSSCGDLTVWDDKMRCLCNEKAHDLGVT 184
Query 194 IFDIIS 199
DI S
Sbjct 185 CCDISS 190
>sp|Q54S59|SKI8_DICDI Superkiller complex protein 8 OS=Dictyostelium
discoideum OX=44689 GN=skic8 PE=3 SV=1
Length=299
Score = 44.7 bits (104), Expect = 0.002, Method: Composition-based stats.
Identities = 37/195 (19%), Positives = 73/195 (37%), Gaps = 20/195 (10%)
Query 46 DAASCMTVHDKFLALGTHYGKVYLLDVQGNITQ------KFDVSPVKINQISLDESGEHM 99
D C+ +A G KV GN Q FD + + + +D ++
Sbjct 14 DGIWCVKWQGDIIATGGMGTKVKTW--HGNQPQFLTERKVFDKHILGVTSLDIDIGARYL 71
Query 100 GVCSEDGKVQVFGLYSGEEFHETFDC-PIKIIAVHPHFVRSSCKQF-VTGGKKLLLFERS 157
DG V++F L + H+T D P+ + F+ S+ V+ + ++
Sbjct 72 ATGGMDGTVRLFDLSTN-TLHKTIDSGPLG--CLKIGFLNSANNLVSVSESGNISIYSVE 128
Query 158 WMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKI-FDIISKQRITNVPRDDISLRPD 216
+ +S + ++ IA A G + +D+ S +R++ + + +R
Sbjct 129 TGEKLRSISNTNKQVLTMAISPNNEQIAVAGLDGTVLCYDVESGRRVSEIKAHGVPIR-- 186
Query 217 MYPCSLCWKDNVTLI 231
SLC+ + I
Sbjct 187 ----SLCFSSDSKTI 197
>sp|C5MIB1|RTC1_CANTT Restriction of telomere capping protein
1 OS=Candida tropicalis (strain ATCC MYA-3404 / T1) OX=294747
GN=RTC1 PE=3 SV=1
Length=1110
Score = 45.5 bits (106), Expect = 0.003, Method: Composition-based stats.
Identities = 39/247 (16%), Positives = 83/247 (34%), Gaps = 43/247 (17%)
Query 12 LEESTDESEEEESEEEPKLKY-ERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLL 70
+ ES ++ + E K Y R+ + + + + ++ +A G G V +
Sbjct 108 ISESQQRIIDDINLLESKSIYNSRVGSKLIN------INTIKTYESTIATGLSNGVVSVY 161
Query 71 DV----QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE-----EFHE 121
+ QG T +F IN + ES + S+DG ++++ L S
Sbjct 162 KISPNGQGKQTGRFSDHKRTINSLDFIESENQLLSGSQDGTIKLWDLRSSSSKPSITIQA 221
Query 122 TFDC-PIKIIAVHPHFVRSSCKQFVT----------------GGKKLLLFERSWMNRWKS 164
+ PI+ PH + ++ G + E+ W
Sbjct 222 SMRSDPIRACQYSPHSSVKNKMCVLSVHDSGALCKFDLRSTGGNGNIYSPEKKW------ 275
Query 165 AVLHEGEG-NIRSVKWRGHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLC 223
LH G ++ + ++I + + +F+ Q ++ P + I + +
Sbjct 276 -NLHTGPALSLHIHPEKEYVITGGRDQRISVFNYGEGQSNSSTPENTIITYGPVL--KVR 332
Query 224 WKDNVTL 230
W +
Sbjct 333 WSSYSNI 339
>sp|G5EEG7|SMU1_CAEEL Smu-1 suppressor of mec-8 and unc-52 protein
OS=Caenorhabditis elegans OX=6239 GN=smu-1 PE=1 SV=1
Length=510
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 33/189 (17%), Positives = 63/189 (33%), Gaps = 26/189 (14%)
Query 57 FLALGTHYGKVYLLDVQGNITQ---------KFDVSPVKINQISLDESGEHMGVCSEDGK 107
+L G+ G + + + + + + IS E + S DGK
Sbjct 228 YLVSGSKDGFIEVWNYMNGKLRKDLKYQAQDNLMMMDAAVRCISFSRDSEMLATGSIDGK 287
Query 108 VQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLL----------LFERS 157
++V+ + +G+ FD F + + G ++ L E
Sbjct 288 IKVWKVETGDCLR-RFDRAHTKGVCAVRFSKDNSHILSGGNDHVVRVHGMKSGKCLKEMR 346
Query 158 WMNRWKSAVLHEGEGN-IRSVKWRGHLIAWANNMG--VKIFDIISKQ--RITNVPRDDIS 212
+ + + V + EGN I S G + W G + F + S+ + +P
Sbjct 347 GHSSYITDVRYSDEGNHIISCSTDGSIRVWHGKSGECLSTFRVGSEDYPILNVIPIPKSD 406
Query 213 LRPDMYPCS 221
P M C+
Sbjct 407 P-PQMIVCN 414
>sp|B4M4W4|WDR55_DROVI WD repeat-containing protein 55 homolog
OS=Drosophila virilis OX=7244 GN=GJ10153 PE=3 SV=1
Length=504
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 37/209 (18%), Positives = 77/209 (37%), Gaps = 28/209 (13%)
Query 39 VTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDV---QGNITQKFDVSPVKINQISLD 93
EI +D + + H +AL T G V+L + + + + +V +
Sbjct 152 PPEIKLEDFITDICFHPDRDIIALATIIGDVHLYEYGNEENKLLRTIEVHAKACRDVEFT 211
Query 94 ESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRS----SCKQFVTGGK 149
E G + CS+D V V + + E+ + ++ H + + F TG
Sbjct 212 EDGRSLITCSKDKCVMVTDMET-EKLKKLYE------TAHDDAINKLHVLDERLFATGDD 264
Query 150 KLLLFERSWMNRWKSAV--LHEGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRIT 204
+ + W R K A+ L E E I + L+A + + + ++I +++
Sbjct 265 AGTV--KLWDFRTKDAIFELKEVEDQITQMLTNEQNKLLLATSADGYLTTYNIGARKLYV 322
Query 205 NVPRDDISLRPDMYPCSLCWKDNVTLIIG 233
+ + C ++ + L+ G
Sbjct 323 QSEPYE-----EELNCMGIYRGSSKLVAG 346
>sp|O13955|VAM6_SCHPO Vacuolar morphogenesis protein 6 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=vam6
PE=3 SV=1
Length=905
Score = 44.7 bits (104), Expect = 0.004, Method: Composition-based stats.
Identities = 54/344 (16%), Positives = 117/344 (34%), Gaps = 48/344 (14%)
Query 523 NYGNALEIYLTLRHKDVFQLIHKHNLFSSIKD---KIVLLMDFDSEKAVDMLLDNEDKIS 579
Y L YL ++ LI K++ +D IV+ +D +SE IS
Sbjct 575 KYEPILS-YLEKLSPELDHLIFKYSRVPLSEDPQNSIVIFIDENSE---------ASTIS 624
Query 580 IKKVVEELEDRP-ELQHVYLHKLFKRDHHKGQRYHEKQISLY----------AEYDRP-- 626
V++ LE ++ +YL KL + + + LY ++
Sbjct 625 KGVVLKYLETISYKVSIIYLEKLLLDNKFNDTVFPTRLALLYLKRILELEETTDFKNQEV 684
Query 627 ------NLLPFLRDSTHCPLEKAL-EICQQRNFVEET-VYLLSRMGNSRSALKMIMEELH 678
L +L +S L EI Q F+ + L R+ + AL + ++ L+
Sbjct 685 FKQTIEKLEDYLTNSKQYDANVVLQEINSQDEFLSTVSIILYRRLSRHQDALDVYLKILN 744
Query 679 DVDKAIEFA----KEQDDGELWEDLILYSID----KPPFITGLLNNIGTHVDPILLIHRI 730
D + A+ + + E + L+ I + + +D + +
Sbjct 745 DWEGALSYCNSVYSIDGETEPYYMLLAEISKNYKSGSLNILDFITKYSSRLDLNRVFPLL 804
Query 731 KEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENI 790
+ + + + + ++ +E K+ L +++ + + + V++ E
Sbjct 805 PKNISMKSYHSLFSSQFRQLFEELSNKETQSKLYQKRLEDLNEELTKVRSEKVVITREKT 864
Query 791 CESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQF 834
C C + S + +F + H C ++ +
Sbjct 865 CLFCHKRLGKSV------ISIFPDGSVVHYGCAKKYVSSNHLPY 902
>sp|Q26544|WSL17_SCHMA WD repeat-containing protein SL1-17 OS=Schistosoma
mansoni OX=6183 PE=2 SV=1
Length=301
Score = 43.9 bits (102), Expect = 0.004, Method: Composition-based stats.
Identities = 33/194 (17%), Positives = 73/194 (38%), Gaps = 21/194 (11%)
Query 56 KFLALGTHYGKVYLLDVQGNIT-QKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
+FLA G+H G V +++VQ + + ++ G + + +G V + L
Sbjct 116 RFLATGSHTGCVNMINVQTAQKEGSIQLEGKFVYXLAYISDGSKLAAGTINGLVSICDLE 175
Query 115 SGE-EFHETFDCPIKIIAVHPH-------FVRSSCKQFVTGGKKLLLFERSWMNRWKSAV 166
+G +F + P++ ++ P K F +L++ + W +V
Sbjct 176 TGSVQFLDGHATPVRSVSFSPDGRLLASASDDKQIKVFDVRDGRLVIPSLNGHKGWVVSV 235
Query 167 LHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKD 226
+ HL+ + + V+I+D+ SK+ + + Y +
Sbjct 236 DFASD--------NRHLVTASTDCSVRIWDLASKEEKHCFNTHEDQVWCARYSP----QG 283
Query 227 NVTLIIGWGTSVKV 240
N + +G S+ +
Sbjct 284 NNIISVGDDRSIMI 297
>sp|Q4R8E7|DAW1_MACFA Dynein assembly factor with WD repeat domains
1 OS=Macaca fascicularis OX=9541 GN=DAW1 PE=2 SV=1
Length=415
Score = 44.3 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 34/217 (16%), Positives = 73/217 (34%), Gaps = 16/217 (7%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
+A G+ L ++Q G +I +S + SG+ + S D V V+
Sbjct 190 TLVATGSMDTTAKLWNIQNGEEVCTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDAD 249
Query 115 SGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTG--GKKLLLFERSWMNRWKSAVLHEGEG 172
+G + + + C +TG K +L++ + + H+ E
Sbjct 250 TGGKVNILIG---HCAEISSALFNWDCSLILTGSMDKTCMLWDATNGKCVATLTGHDDEI 306
Query 173 NIRSVKWRGHLIAWANNMGV-KIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLI 231
+ G LIA A+ G +IF +++ I + + + + L+
Sbjct 307 LDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQ-----GNRLL 361
Query 232 IGWGTSVKVCSVKERHASEMRDLPSRYVEIV--SQFE 266
G K + + + + + + + F
Sbjct 362 TGSSD--KTARIWDAQTGQCLQVLEGHTDEIFSCTFN 396
>sp|B4PU14|WDR55_DROYA WD repeat-containing protein 55 homolog
OS=Drosophila yakuba OX=7245 GN=GE24201 PE=3 SV=1
Length=499
Score = 44.3 bits (103), Expect = 0.004, Method: Composition-based stats.
Identities = 22/112 (20%), Positives = 44/112 (39%), Gaps = 8/112 (7%)
Query 12 LEESTDESEEEESEEEPKLKYERLS---NGVTEILQKDAASCMTVH--DKFLALGTHYGK 66
E + D ++E++E + + + EI +D + + H +AL T G
Sbjct 120 SEATFDLDVDDETDETVRAMIAAIKKPRSAPPEIKLEDFITDICFHPDRDIIALATIIGD 179
Query 67 VYLLDVQG---NITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYS 115
V+L + + + +V + E G + CS+D V V + +
Sbjct 180 VHLYEYDNEANKLLRTIEVHSKACRDVEFTEDGRFLLTCSKDKCVMVTDMET 231
>sp|Q8N9V3|WSDU1_HUMAN WD repeat, SAM and U-box domain-containing
protein 1 OS=Homo sapiens OX=9606 GN=WDSUB1 PE=1 SV=4
Length=476
Score = 43.9 bits (102), Expect = 0.006, Method: Composition-based stats.
Identities = 21/165 (13%), Positives = 50/165 (30%), Gaps = 14/165 (8%)
Query 46 DAASCMTVHDKFLALGTHYGKVYLL---DVQGNITQKFDVSPVKINQISLDESGEHMGVC 102
D +C LA + + L D ++ SG + C
Sbjct 13 DDVNCCAFSFSLLATCSLDKTIRLYSLRDFTELPHSPLKFHTYAVHCCCFSPSGHILASC 72
Query 103 SEDGKVQVFGLYSGEE---FHETFDCPIKIIAVHPHFVRSSCKQFVTG--GKKLLLFERS 157
S DG ++ +G+ + P+++ P +G ++L+
Sbjct 73 STDGTTVLWNTENGQMLAVMEQPSGSPVRVCQFSPD-----STCLASGAADGTVVLWNAQ 127
Query 158 WMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMG-VKIFDIISKQ 201
++ + +G + G ++ G + ++D +
Sbjct 128 SYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRC 172
>sp|Q8W117|SMU1_ARATH Suppressor of mec-8 and unc-52 protein homolog
1 OS=Arabidopsis thaliana OX=3702 GN=SMU1 PE=1 SV=1
Length=511
Score = 43.9 bits (102), Expect = 0.006, Method: Composition-based stats.
Identities = 21/95 (22%), Positives = 41/95 (43%), Gaps = 6/95 (6%)
Query 30 LKYERLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQ-GNITQKFDVSPVK 86
L+Y+ + ++ D C+ + LA G+ GK+ + ++ G ++FD
Sbjct 251 LQYQ---ADESFMMHDDPVLCIDFSRDSEMLASGSQDGKIKIWRIRTGVCIRRFDAHSQG 307
Query 87 INQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE 121
+ +S G + S D ++ GL SG+ E
Sbjct 308 VTSLSFSRDGSQLLSTSFDQTARIHGLKSGKLLKE 342
>sp|Q29HG9|LST8_DROPS Protein LST8 homolog OS=Drosophila pseudoobscura
pseudoobscura OX=46245 GN=GA15597 PE=3 SV=1
Length=315
Score = 43.5 bits (101), Expect = 0.006, Method: Composition-based stats.
Identities = 40/200 (20%), Positives = 75/200 (38%), Gaps = 18/200 (9%)
Query 67 VYLLDVQGNITQ---KFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHET- 122
+ L D++ N T FD + ++ E G M ED V+++ + S
Sbjct 58 IRLYDLESNCTAPVINFDGVQKNVTRLGFQEDGNWMFTAGEDHHVRIWDMISAPPHCSRV 117
Query 123 FDC--PIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIR--SVK 178
FDC P+ +HP+ V + + L++ + ++ E + +I+ ++
Sbjct 118 FDCESPVNAACLHPNQVEIGMG---SQNGNVFLWDVK--SEKHECIVPEVDASIQDVAIS 172
Query 179 WRGHLIAWANNMGV----KIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGW 234
GH +A ANN G + ++ T P I Y + + L++
Sbjct 173 PDGHYLAAANNKGNCYIWSLCSSPDQKMSTMRPTKKIQAH-TRYILRCKFSPDSRLLLTT 231
Query 235 GTSVKVCSVKERHASEMRDL 254
C K S+ R+L
Sbjct 232 SGDGTACLWKTSDFSKWREL 251
Score = 36.2 bits (82), Expect = 1.2, Method: Composition-based stats.
Identities = 24/128 (19%), Positives = 51/128 (40%), Gaps = 14/128 (11%)
Query 48 ASCMTVHDKFLALGTHYGKVYLLD----VQGNITQKFDVSPVKINQISLDESGEHMGVCS 103
A+C+ + + +G+ G V+L D I + D S I +++ G ++ +
Sbjct 126 AACLHPNQVEIGMGSQNGNVFLWDVKSEKHECIVPEVDAS---IQDVAISPDGHYLAAAN 182
Query 104 EDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRS-----SCKQFVT--GGKKLLLFER 156
G ++ L S + + P K I H ++ + +T G L++
Sbjct 183 NKGNCYIWSLCSSPDQKMSTMRPTKKIQAHTRYILRCKFSPDSRLLLTTSGDGTACLWKT 242
Query 157 SWMNRWKS 164
S ++W+
Sbjct 243 SDFSKWRE 250
>sp|P49695|PKWA_THECU Probable serine/threonine-protein kinase
PkwA OS=Thermomonospora curvata OX=2020 GN=pkwA PE=1 SV=1
Length=742
Score = 43.9 bits (102), Expect = 0.006, Method: Composition-based stats.
Identities = 30/175 (17%), Positives = 63/175 (36%), Gaps = 22/175 (13%)
Query 57 FLALGTHYGKVYLLDVQGNITQK-FDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYS 115
LA G+ V L DV + F+ + I+ G + S DG +++ + +
Sbjct 515 LLASGSDDATVRLWDVAAAEERAVFEGHTHYVLDIAFSPDGSMVASGSRDGTARLWNVAT 574
Query 116 GEEF-----HETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSW---MNRWKSAVL 167
G E H + + +A P +G + + R W + + VL
Sbjct 575 GTEHAVLKGHTDY---VYAVAFSPD-----GSMVASGSRDGTI--RLWDVATGKERD-VL 623
Query 168 HEGEGNIRSVKWR--GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPC 220
N+ S+ + G ++ ++ V ++D+ S + + +R +
Sbjct 624 QAPAENVVSLAFSPDGSMLVHGSDSTVHLWDVASGEALHTFEGHTDWVRAVAFSP 678
>sp|Q8T088|WDR55_DROME WD repeat-containing protein 55 homolog
OS=Drosophila melanogaster OX=7227 GN=CG14722 PE=2 SV=1
Length=498
Score = 43.5 bits (101), Expect = 0.007, Method: Composition-based stats.
Identities = 37/210 (18%), Positives = 79/210 (38%), Gaps = 28/210 (13%)
Query 38 GVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQG---NITQKFDVSPVKINQISL 92
EI +D + + H +AL T G V+L + + + +V +
Sbjct 149 SPPEIKLEDFITDICFHPDRDIIALATIIGDVHLYEYDNEANKLLRTIEVHSKACRDVEF 208
Query 93 DESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRS----SCKQFVTGG 148
E G + CS+D V V + + E+ + ++ H + + + F +G
Sbjct 209 TEDGRFLLTCSKDKCVMVTDMET-EKLKKLYE------TAHDDAINTLHVLNENLFASGD 261
Query 149 KKLLLFERSWMNRWKSAV--LHEGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRI 203
+ + W R K+A+ L E E I + L+A + + + F+I +++
Sbjct 262 DAGTV--KLWDLRTKNAIFELKELEDQITQLTTNEQSKLLLATSADGYLTTFNISARKMY 319
Query 204 TNVPRDDISLRPDMYPCSLCWKDNVTLIIG 233
+ + C ++ + L++G
Sbjct 320 VQSEPYE-----EELNCMGVYRGDSKLVVG 344
>sp|Q297N8|HPS5_DROPS BLOC-2 complex member HPS5 homolog OS=Drosophila
pseudoobscura pseudoobscura OX=46245 GN=p PE=3 SV=1
Length=830
Score = 43.9 bits (102), Expect = 0.007, Method: Composition-based stats.
Identities = 30/190 (16%), Positives = 64/190 (34%), Gaps = 18/190 (9%)
Query 35 LSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDE 94
LS + + +C + D ++ G G +YL + G I +S+
Sbjct 15 LSLSLPLKHNRIKYTCFDISDSYIIFGASSGSLYLFNRNGKFLHLIPNKHGAITNLSISA 74
Query 95 SGEHMGVCSEDG-----KVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGK 149
+ +++ ++ V + + + D +++ +H KQF G
Sbjct 75 NNKYVAFSTQRSLICVYVVNLSAQATPQVIVTHLDQSVQVSCIH---WTQDEKQFYYGDS 131
Query 150 ----KLLLFER----SWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISK- 200
L+L S + L + I + L+ +N + + +
Sbjct 132 RGQVNLVLLSSFIGHSLLLNMTVHPLLYLDSPIVQIDDFESLLLVSNCTKCILCNTEYEE 191
Query 201 -QRITNVPRD 209
++I N PRD
Sbjct 192 YKQIGNRPRD 201
>sp|Q5ZMA2|PRP19_CHICK Pre-mRNA-processing factor 19 OS=Gallus
gallus OX=9031 GN=PRPF19 PE=1 SV=1
Length=505
Score = 43.5 bits (101), Expect = 0.007, Method: Composition-based stats.
Identities = 24/132 (18%), Positives = 49/132 (37%), Gaps = 12/132 (9%)
Query 34 RLSNGVTEILQKDAASCMTVHDKFLALGT--HYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
R+ VT+ A +C H L GT ++ + D++ F I I
Sbjct 340 RVLTKVTDESSGCALTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSI 399
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFHE---TFDCPIKIIAVHPHFVRSSCKQFVTG 147
+ E+G ++ ++D V+++ L + F + +K + S G
Sbjct 400 AFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFD-----QSGTYLALG 454
Query 148 GKKLLLFE-RSW 158
G + ++ + W
Sbjct 455 GTDVQIYICKQW 466
>sp|P0CS46|PFS2_CRYNJ Polyadenylation factor subunit 2 OS=Cryptococcus
neoformans var. neoformans serotype D (strain JEC21
/ ATCC MYA-565) OX=214684 GN=PFS2 PE=3 SV=1
Length=712
Score = 43.9 bits (102), Expect = 0.007, Method: Composition-based stats.
Identities = 36/203 (18%), Positives = 73/203 (36%), Gaps = 21/203 (10%)
Query 30 LKYERLSNGVTEILQKDAASCMTVHDKFLALGTHY--GKVYLLDVQGNITQKFDVSPVKI 87
YE ++ + D+ T AL + G + F
Sbjct 165 FNYESITQ-----VHDDSIRSFTYSHNGQALVSADKGGTIKYFTPHLTNIHGFQGHREAC 219
Query 88 NQISLDESGEHMGVCSEDGKVQVFGLYS--GEEFHETFDCPIKIIAVHPHFVRSSCKQFV 145
+ +S + E C +DG V+++ E ++ + HP + V
Sbjct 220 HDVSWSPNDERFVTCGDDGLVKIWSYREAKEERSLSGHGWDVRCVDWHP-----TKGLIV 274
Query 146 TGGKKLLLFERSWMNRW-KS-AVLHEGEGNIRSVKWR--GHLIAWA-NNMGVKIFDIISK 200
+G K +L+ + W R K + LH + I + +W GHL+A A + +++FDI +
Sbjct 275 SGSKDMLV--KFWDPRTGKDLSTLHSSKSTINTCRWSPDGHLVATAGQDSVIRLFDIRTF 332
Query 201 QRITNVPRDDISLRPDMYPCSLC 223
+ + + + + +
Sbjct 333 RELEVLKGHEKEVNCIEWHPIHH 355
>sp|P0CS47|PFS2_CRYNB Polyadenylation factor subunit 2 OS=Cryptococcus
neoformans var. neoformans serotype D (strain B-3501A)
OX=283643 GN=PFS2 PE=3 SV=1
Length=713
Score = 43.9 bits (102), Expect = 0.007, Method: Composition-based stats.
Identities = 36/203 (18%), Positives = 73/203 (36%), Gaps = 21/203 (10%)
Query 30 LKYERLSNGVTEILQKDAASCMTVHDKFLALGTHY--GKVYLLDVQGNITQKFDVSPVKI 87
YE ++ + D+ T AL + G + F
Sbjct 165 FNYESITQ-----VHDDSIRSFTYSHNGQALVSADKGGTIKYFTPHLTNIHGFQGHREAC 219
Query 88 NQISLDESGEHMGVCSEDGKVQVFGLYS--GEEFHETFDCPIKIIAVHPHFVRSSCKQFV 145
+ +S + E C +DG V+++ E ++ + HP + V
Sbjct 220 HDVSWSPNDERFVTCGDDGLVKIWSYREAKEERSLSGHGWDVRCVDWHP-----TKGLIV 274
Query 146 TGGKKLLLFERSWMNRW-KS-AVLHEGEGNIRSVKWR--GHLIAWA-NNMGVKIFDIISK 200
+G K +L+ + W R K + LH + I + +W GHL+A A + +++FDI +
Sbjct 275 SGSKDMLV--KFWDPRTGKDLSTLHSSKSTINTCRWSPDGHLVATAGQDSVIRLFDIRTF 332
Query 201 QRITNVPRDDISLRPDMYPCSLC 223
+ + + + + +
Sbjct 333 RELEVLKGHEKEVNCIEWHPIHH 355
>sp|Q9VHN9|HPS5_DROME BLOC-2 complex member HPS5 homolog OS=Drosophila
melanogaster OX=7227 GN=p PE=2 SV=1
Length=826
Score = 43.5 bits (101), Expect = 0.008, Method: Composition-based stats.
Identities = 28/176 (16%), Positives = 62/176 (35%), Gaps = 18/176 (10%)
Query 49 SCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDG-- 106
+C + D ++ G G +YL + G I +S+ + +++ ++
Sbjct 30 TCFDISDSYIIFGASSGSLYLFNRNGKFLLLIPNKHGAITSLSISANSKYVAFATQRSLI 89
Query 107 ---KVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKK-----LLLFE--- 155
V + + + D +++ +H KQF G + +LL
Sbjct 90 CVYAVNLSAQATPQVIFTHLDQSVQVTCIH---WTQDEKQFYYGDSRGQVSLVLLSSFIG 146
Query 156 RSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISK--QRITNVPRD 209
S + L + I + +L+ +N + + + ++I N PRD
Sbjct 147 HSLLFNMTVHPLLYLDSPIVQIDDFEYLLLVSNCTKCILCNTEYEDYKQIGNRPRD 202
>sp|Q9JMJ4|PRP19_RAT Pre-mRNA-processing factor 19 OS=Rattus norvegicus
OX=10116 GN=Prpf19 PE=1 SV=2
Length=504
Score = 43.2 bits (100), Expect = 0.009, Method: Composition-based stats.
Identities = 23/132 (17%), Positives = 49/132 (37%), Gaps = 12/132 (9%)
Query 34 RLSNGVTEILQKDAASCMTVHDKFLALGT--HYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
R+ VT+ + +C H L GT ++ + D++ F I I
Sbjct 339 RVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSI 398
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFHE---TFDCPIKIIAVHPHFVRSSCKQFVTG 147
+ E+G ++ ++D V+++ L + F + +K + S G
Sbjct 399 AFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFD-----QSGTYLALG 453
Query 148 GKKLLLFE-RSW 158
G + ++ + W
Sbjct 454 GTDVQIYICKQW 465
Score = 35.1 bits (79), Expect = 3.2, Method: Composition-based stats.
Identities = 26/175 (15%), Positives = 62/175 (35%), Gaps = 19/175 (11%)
Query 48 ASCMTVH--DKFLALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSE 104
+ + H + + + + + V + Q + +SL +G+++ S+
Sbjct 267 VTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSD 326
Query 105 DGKVQVFGLYSGEEFH----ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMN 160
D + +G ET C + HP + G + + W
Sbjct 327 DQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPD-------GLIFGTGTMDSQIKIWDL 379
Query 161 RWKSAVLH--EGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRITNVPRDD 210
+ ++ V + G I S+ + + L A++ VK++D+ + + D+
Sbjct 380 KERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDN 434
>sp|Q99KP6|PRP19_MOUSE Pre-mRNA-processing factor 19 OS=Mus musculus
OX=10090 GN=Prpf19 PE=1 SV=1
Length=504
Score = 43.2 bits (100), Expect = 0.009, Method: Composition-based stats.
Identities = 23/132 (17%), Positives = 49/132 (37%), Gaps = 12/132 (9%)
Query 34 RLSNGVTEILQKDAASCMTVHDKFLALGT--HYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
R+ VT+ + +C H L GT ++ + D++ F I I
Sbjct 339 RVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSI 398
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFHE---TFDCPIKIIAVHPHFVRSSCKQFVTG 147
+ E+G ++ ++D V+++ L + F + +K + S G
Sbjct 399 AFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFD-----QSGTYLALG 453
Query 148 GKKLLLFE-RSW 158
G + ++ + W
Sbjct 454 GTDVQIYICKQW 465
Score = 35.1 bits (79), Expect = 3.2, Method: Composition-based stats.
Identities = 26/175 (15%), Positives = 62/175 (35%), Gaps = 19/175 (11%)
Query 48 ASCMTVH--DKFLALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSE 104
+ + H + + + + + V + Q + +SL +G+++ S+
Sbjct 267 VTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSD 326
Query 105 DGKVQVFGLYSGEEFH----ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMN 160
D + +G ET C + HP + G + + W
Sbjct 327 DQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPD-------GLIFGTGTMDSQIKIWDL 379
Query 161 RWKSAVLH--EGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRITNVPRDD 210
+ ++ V + G I S+ + + L A++ VK++D+ + + D+
Sbjct 380 KERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDN 434
>sp|Q9UMS4|PRP19_HUMAN Pre-mRNA-processing factor 19 OS=Homo sapiens
OX=9606 GN=PRPF19 PE=1 SV=1
Length=504
Score = 43.2 bits (100), Expect = 0.009, Method: Composition-based stats.
Identities = 23/132 (17%), Positives = 49/132 (37%), Gaps = 12/132 (9%)
Query 34 RLSNGVTEILQKDAASCMTVHDKFLALGT--HYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
R+ VT+ + +C H L GT ++ + D++ F I I
Sbjct 339 RVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSI 398
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFHE---TFDCPIKIIAVHPHFVRSSCKQFVTG 147
+ E+G ++ ++D V+++ L + F + +K + S G
Sbjct 399 AFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFD-----QSGTYLALG 453
Query 148 GKKLLLFE-RSW 158
G + ++ + W
Sbjct 454 GTDVQIYICKQW 465
Score = 34.7 bits (78), Expect = 4.3, Method: Composition-based stats.
Identities = 26/175 (15%), Positives = 61/175 (35%), Gaps = 19/175 (11%)
Query 48 ASCMTVH--DKFLALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSE 104
+ + H + + + + V + Q + +SL +G+++ S+
Sbjct 267 VTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSD 326
Query 105 DGKVQVFGLYSGEEFH----ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMN 160
D + +G ET C + HP + G + + W
Sbjct 327 DQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPD-------GLIFGTGTMDSQIKIWDL 379
Query 161 RWKSAVLH--EGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRITNVPRDD 210
+ ++ V + G I S+ + + L A++ VK++D+ + + D+
Sbjct 380 KERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDN 434
>sp|Q08E38|PRP19_BOVIN Pre-mRNA-processing factor 19 OS=Bos taurus
OX=9913 GN=PRPF19 PE=2 SV=1
Length=504
Score = 43.2 bits (100), Expect = 0.009, Method: Composition-based stats.
Identities = 23/132 (17%), Positives = 49/132 (37%), Gaps = 12/132 (9%)
Query 34 RLSNGVTEILQKDAASCMTVHDKFLALGT--HYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
R+ VT+ + +C H L GT ++ + D++ F I I
Sbjct 339 RVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSI 398
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFHE---TFDCPIKIIAVHPHFVRSSCKQFVTG 147
+ E+G ++ ++D V+++ L + F + +K + S G
Sbjct 399 AFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFD-----QSGTYLALG 453
Query 148 GKKLLLFE-RSW 158
G + ++ + W
Sbjct 454 GTDVQIYICKQW 465
Score = 35.8 bits (81), Expect = 2.1, Method: Composition-based stats.
Identities = 26/175 (15%), Positives = 62/175 (35%), Gaps = 19/175 (11%)
Query 48 ASCMTVH--DKFLALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSE 104
+ + H + + + + + V + Q + +SL +G+++ S+
Sbjct 267 VTSVVFHPSQELVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSD 326
Query 105 DGKVQVFGLYSGEEFH----ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMN 160
D + +G ET C + HP + G + + W
Sbjct 327 DQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPD-------GLIFGTGTMDSQIKIWDL 379
Query 161 RWKSAVLH--EGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRITNVPRDD 210
+ ++ V + G I S+ + + L A++ VK++D+ + + D+
Sbjct 380 KERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDN 434
>sp|A4REK3|SEC13_PYRO7 Protein transport protein SEC13 OS=Pyricularia
oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) OX=242507
GN=SEC13 PE=3 SV=3
Length=289
Score = 42.8 bits (99), Expect = 0.010, Method: Composition-based stats.
Identities = 38/148 (26%), Positives = 59/148 (40%), Gaps = 24/148 (16%)
Query 33 ERLSNGVTEILQKDAASCMT-VHDKF---LALGTHYGKVYLLDVQGNITQK---FDVSPV 85
RL+ + + A C+ H K+ LA + GKV++ QG QK F +
Sbjct 33 HRLTETLKG--HEGAVWCVAWAHPKYGNILASSGYDGKVFIWREQGGAWQKIFDFALHKA 90
Query 86 KINQISLD--ESGEHMGVCSEDGKVQVFGLYSGEEFHETF---DCPIKIIAVHP------ 134
+N +S ESG + S DG V V H+TF + ++ P
Sbjct 91 SVNIVSWSPHESGCLLACASSDGHVSVLEFKDNSFDHQTFLAHGQGVNSVSWAPSTAPGS 150
Query 135 ----HFVRSSCKQFVTGGKKLLLFERSW 158
+ ++ ++FVTGG L SW
Sbjct 151 IISTNATPAAQRRFVTGGSDNTLKIWSW 178
>sp|Q9LFI1|PP280_ARATH Pentatricopeptide repeat-containing protein
At3g53360, mitochondrial OS=Arabidopsis thaliana OX=3702
GN=PCMP-E86 PE=2 SV=1
Length=768
Score = 43.2 bits (100), Expect = 0.011, Method: Composition-based stats.
Identities = 47/233 (20%), Positives = 83/233 (36%), Gaps = 29/233 (12%)
Query 336 HLEYSEGESLFYIVSPRDVV--VAKERDQDDHIDWLLEKKKYEEALMAAEISQKNI---- 389
L S I++ VV + E +DHI+ L + Y EAL A + +QKN
Sbjct 6 RLGARVSVSNSQILATSSVVSTIKTEELMNDHINSLCKSNFYREALEAFDFAQKNSSFKI 65
Query 390 ------------KRHKILDIGLAYINHLVERG-DYDI-AARKCQKILGKNAALWE-YEVY 434
+ L G +H++ YD + GK +L + EV+
Sbjct 66 RLRTYISLICACSSSRSLAQGRKIHDHILNSNCKYDTILNNHILSMYGKCGSLRDAREVF 125
Query 435 KFKEIGQLK----AISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNN 490
F L I+ Y G +Y +L E L D F ++I+ ++
Sbjct 126 DFMPERNLVSYTSVITGYSQNGQGAEAIRLYLKMLQEDLVPDQFAFGSIIKACASS--SD 183
Query 491 SVIVQAVRDHLKKDSQNKTLL--KTLAELYTYDKNYGNALEIYLTLRHKDVFQ 541
+ + + + K + L+ L +Y +A ++ + KD+
Sbjct 184 VGLGKQLHAQVIKLESSSHLIAQNALIAMYVRFNQMSDASRVFYGIPMKDLIS 236
>sp|Q7KWK5|PRP19_DICDI Pre-mRNA-processing factor 19 OS=Dictyostelium
discoideum OX=44689 GN=prp19 PE=3 SV=1
Length=514
Score = 43.2 bits (100), Expect = 0.011, Method: Composition-based stats.
Identities = 31/141 (22%), Positives = 55/141 (39%), Gaps = 15/141 (11%)
Query 49 SCMTVHDK--FLALGTHYGKVYLLDVQGNITQ-KFDVSPVKINQISLDESGEHMGVCSED 105
+ + H F A GT G V + D++ + F +N IS E+G + +++
Sbjct 356 TSVAFHPDGMFFAAGTQNGVVKIFDLKSKVNSFNFQGLSTAVNCISFSENG-YYLTAADN 414
Query 106 GKVQVFGL------YSGEEFHETFD-CPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSW 158
V++F L S + T D IK I +F SS V ++ L+
Sbjct 415 NTVKLFDLRKAATKNSPDIQTITLDNQQIKSI----NFDYSSQYLGVASSNQINLYSCKS 470
Query 159 MNRWKSAVLHEGEGNIRSVKW 179
+ + +H + + KW
Sbjct 471 KQKPPISSIHSIDSDCLDFKW 491
>sp|Q4P9P9|LIS1_MYCMD Nuclear distribution protein PAC1 OS=Mycosarcoma
maydis OX=5270 GN=PAC1 PE=3 SV=1
Length=453
Score = 43.2 bits (100), Expect = 0.011, Method: Composition-based stats.
Identities = 26/190 (14%), Positives = 68/190 (36%), Gaps = 30/190 (16%)
Query 48 ASCMTVHDKF--LALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSE 104
+ ++ H F +A + V L D + G+ + + + D G ++ CS
Sbjct 125 VTKVSFHPVFSQIASASEDTTVKLWDWETGDFERTLKGHTKAVQDVDFDSKGNYVLSCSS 184
Query 105 DGKVQV---FGLYSGEEFHETFDCPIKIIAVHP--HFVRSSCK-------QFVTGGKKLL 152
D ++V Y + + D + + P ++ S+ + +F TG
Sbjct 185 DLSIKVWDANNDYKNIKTLQGHDHSVSSVRFLPGDDYIVSASRDKTIKIWEFSTG----- 239
Query 153 LFERSWMN--RWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITNVPRDD 210
++ W + + + KW L++ + + +++D+ S + + +
Sbjct 240 FCTKTLQGHAEWVRSAIPSDDA-----KW---LVSCSTDQTARVWDVSSGETKVELRGHE 291
Query 211 ISLRPDMYPC 220
+ ++
Sbjct 292 HVVEVAIFAP 301
>sp|B3P4F8|WDR55_DROER WD repeat-containing protein 55 homolog
OS=Drosophila erecta OX=7220 GN=GG18443 PE=3 SV=1
Length=498
Score = 43.2 bits (100), Expect = 0.011, Method: Composition-based stats.
Identities = 38/209 (18%), Positives = 79/209 (38%), Gaps = 28/209 (13%)
Query 39 VTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQG---NITQKFDVSPVKINQISLD 93
EI +D + + H +AL T G V+L + + + +V +
Sbjct 151 PPEIKLEDFITDICFHPDRDIIALATIIGDVHLYEYDNEANKLLRTIEVHSKACRDVEFT 210
Query 94 ESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRS----SCKQFVTGGK 149
E G + CS+D V V + + E+ + ++ H + + + F TG
Sbjct 211 EDGRFLLTCSKDKCVMVTDMET-EKLKKLYE------TAHDDAINTLHVLNENLFATGDD 263
Query 150 KLLLFERSWMNRWKSAV--LHEGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRIT 204
+ + W R K+A+ L E E I + L+A + + + F+I +++
Sbjct 264 AGTV--KLWDLRTKNAIFELKELEDQITQLTTNDQSKLLLATSADGYLTTFNIAARKMYV 321
Query 205 NVPRDDISLRPDMYPCSLCWKDNVTLIIG 233
+ + C ++ + L++G
Sbjct 322 QSEPYE-----EELSCMGIYRGDSKLVVG 345
>sp|Q8N136|DAW1_HUMAN Dynein assembly factor with WD repeat domains
1 OS=Homo sapiens OX=9606 GN=DAW1 PE=1 SV=1
Length=415
Score = 42.8 bits (99), Expect = 0.012, Method: Composition-based stats.
Identities = 37/211 (18%), Positives = 75/211 (36%), Gaps = 18/211 (9%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
+A G+ L D+Q G +I +S + SG+ + S D V V+
Sbjct 190 TLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDAD 249
Query 115 SGEEFHETFDC--PIKIIAVHPHFVRSSCKQFVTG--GKKLLLFERSWMNRWKSAVLHEG 170
+G + + I + + C +TG K L++ + + H+
Sbjct 250 TGRKVNILIGHCAEISSASFNWD-----CSLILTGSMDKTCKLWDATNGKCVATLTGHDD 304
Query 171 EGNIRSVKWRGHLIAWANNMGV-KIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVT 229
E + G LIA A+ G +IF +++ I + + + + + N
Sbjct 305 EILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNP----QGNHL 360
Query 230 LIIGWGTSVKVCSVKERHASEMRDLPSRYVE 260
L G+S K + + + + + +
Sbjct 361 LT---GSSDKTARIWDAQTGQCLQVLEGHTD 388
>sp|A8X8C6|TG125_CAEBR WD repeat-containing protein wdr-5.1 OS=Caenorhabditis
briggsae OX=6238 GN=wdr-5.1 PE=4 SV=1
Length=368
Score = 42.8 bits (99), Expect = 0.012, Method: Composition-based stats.
Identities = 32/231 (14%), Positives = 87/231 (38%), Gaps = 35/231 (15%)
Query 8 ETGSLEESTDESEEEESEEEPKLKYER-LSNGVTEILQKDAASCMTVH--DKFLALGTHY 64
++ S+ ++D+ + E P +K + L + C + + G+
Sbjct 132 DSKSIVTASDDKTLKIYEV-PTVKMAKTLKGHTNYVF------CCNFNPQSSLVVSGSFD 184
Query 65 GKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE---EFH 120
V + DV+ G + ++ +S + G + S DG V+++ +G+
Sbjct 185 ESVRIWDVRTGMCVKTLPAHSDPVSAVSFNRDGSLITSGSYDGLVRIWDTANGQCVKTLV 244
Query 121 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSW-MNRWKSAVLHEG-EGNIRSV- 177
+ + P+ + P+ K ++ L + W + K+ ++G E N +
Sbjct 245 DDENPPVAFVKFSPN-----GKYILSSNLDNTL--KLWDFGKGKTLKQYQGHENNKYCIF 297
Query 178 --------KWRGHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPC 220
KW +I+ + + + ++++ +K+ + ++ ++
Sbjct 298 ANFSVTGGKW---IISGSEDCKIYVWNLQTKEVVQSLEGHTQAVIASDCHP 345
>sp|B4QTL6|WDR55_DROSI WD repeat-containing protein 55 homolog
OS=Drosophila simulans OX=7240 GN=GD18783 PE=3 SV=1
Length=498
Score = 42.8 bits (99), Expect = 0.013, Method: Composition-based stats.
Identities = 37/210 (18%), Positives = 79/210 (38%), Gaps = 28/210 (13%)
Query 38 GVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQG---NITQKFDVSPVKINQISL 92
EI +D + + H +AL T G V+L + + + +V +
Sbjct 149 SPPEIKLEDFITDICFHPDRDIIALATIIGDVHLYEYDNEANKLLRTIEVHSKACRDVEF 208
Query 93 DESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRS----SCKQFVTGG 148
E G + CS+D V V + + E+ + ++ H + + + F +G
Sbjct 209 TEDGRFLLTCSKDKCVMVTDMET-EKLKKLYE------TAHDDAINTLHVLNENLFASGD 261
Query 149 KKLLLFERSWMNRWKSAV--LHEGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRI 203
+ + W R K+A+ L E E I + L+A + + + F+I +++
Sbjct 262 DAGTV--KLWDLRTKNAIFELKELEDQITQLTTNEQSKLLLATSADGYLTTFNISARKMY 319
Query 204 TNVPRDDISLRPDMYPCSLCWKDNVTLIIG 233
+ + C ++ + L++G
Sbjct 320 VQSEPYE-----EELNCMGVYRGDSKLVVG 344
>sp|P25870|CLH_DICDI Clathrin heavy chain OS=Dictyostelium discoideum
OX=44689 GN=chcA PE=1 SV=1
Length=1694
Score = 43.2 bits (100), Expect = 0.013, Method: Composition-based stats.
Identities = 71/479 (15%), Positives = 165/479 (34%), Gaps = 60/479 (13%)
Query 261 IVSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSETCEEISSD 320
I++ FE+ GL Q+VV S E+ K + ++ + D
Sbjct 699 IIAMFESFRLYEGLYLYLTQVVVTSTSPEVHFKYIEAAAKINQFKEVERMCRDSN--YYD 756
Query 321 ALTVRGFQENECRDYHLEYSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEK--KKYEEA 378
R F + L + +S D ++L + KY EA
Sbjct 757 PEKTRDFLKEAKLPDQLPLIIVCDRYEFIS-------------DLTNYLYKNNLSKYIEA 803
Query 379 LMAAEISQKN----IKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVY 434
+I+ N + LD Y+ +L+ C + V
Sbjct 804 Y-VQKINPVNTPLVVGALLDLDCQEDYLRNLIMSVR-----NMCPA---------DSLVE 848
Query 435 KFKEIGQLKAISPYLPR--GDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSV 492
+ ++ +LK + P+L + ++P I+ + +++S+ A L+ Y++ V
Sbjct 849 QVEKRNRLKLLLPWLEARVAEGNIEPAIHNALAKIYIDSNKNPEAFLLHN---QFYDSKV 905
Query 493 IVQAVRDH---LKKDSQNKTLLK-TLAELYTYDKNYGNALEIYLTLRHKDVFQLI--HKH 546
+ + L + + L L E+ + + N + + D++ + ++
Sbjct 906 VGKYCEKRDPYLSFVAYKRGLCDYELIEVTNKNTLFKNQARYLVERQDPDLWAYVLSDQN 965
Query 547 NLFSSIKDKIVLLMDFDSEKAVDM---LLDNEDKISIKKVVEELEDRPELQHVYLHKLFK 603
S+ D++V +S A ++ + D +++E LE L
Sbjct 966 EYKRSLIDQVVQTALPESTNATEVSATVKAFMDANLPNELIELLEK---------IVLEG 1016
Query 604 RDHHKGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRM 663
++ + I D+ + ++ + K I + EE ++ +
Sbjct 1017 KEFKTAKELQNLLILTAIRADKSRVTDYINRLDNFDGSKLAPIAIESQLYEEAFFMYKKF 1076
Query 664 GNSRSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVD 722
+ A+ +++ + +++A +FA+ + E++ L + K + + + D
Sbjct 1077 QFNVEAIDVLITHIGSIERAHDFAERCNQTEVYSKL-GVAQLKAEMVKECIESFIKAND 1134
Score = 39.7 bits (91), Expect = 0.14, Method: Composition-based stats.
Identities = 33/189 (17%), Positives = 67/189 (35%), Gaps = 17/189 (9%)
Query 510 LLKTLAELYTYDKNYGNALEIYLTLRH--KDVFQLIHKHNLFSSIKDKIVLLMDFDSEKA 567
LL T E Y Y A ++ Q I K I D+ L+ +
Sbjct 362 LLTTQFERYFQQGQYKEAAKVAADSPGSILRNLQTIQKFQSIPPIPDQPSALLQYFGMLL 421
Query 568 VDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQR--YHEKQISL---YAE 622
L+ + + + + V +P L+ + G H+++++L Y
Sbjct 422 EKGKLNKVESLELVRPVLAQGKKPILEKWLTEDKLECSEQLGDEVRPHDRKLALSIYYRA 481
Query 623 YDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDK 682
++ ++ K + C++ N+ + ++LL RM N+ + D
Sbjct 482 NASDKVITLFAETGEFD--KIIAYCKKFNYKPDFMFLLQRMANA--------NPMGAADF 531
Query 683 AIEFAKEQD 691
A++ KE+
Sbjct 532 AVKLVKEEG 540
>sp|Q9FKT5|THOC3_ARATH THO complex subunit 3 OS=Arabidopsis thaliana
OX=3702 GN=THO3 PE=1 SV=1
Length=315
Score = 42.4 bits (98), Expect = 0.013, Method: Composition-based stats.
Identities = 23/111 (21%), Positives = 44/111 (40%), Gaps = 4/111 (4%)
Query 30 LKYERLSNGVTEILQKDAASCMTVHDK--FLALGTHYGKVYLLDVQGNI-TQKFDVSPVK 86
L Y L T C+ + K + A+G+ V L D+ + + F
Sbjct 176 LSYPSLKPLDTLTAHTAGCYCIAIDPKGRYFAVGSADSLVSLWDISDMLCLRTFTKLEWP 235
Query 87 INQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE-TFDCPIKIIAVHPHF 136
+ IS + SGE++ SED + + + +G H+ + + +P +
Sbjct 236 VRTISFNYSGEYIASASEDLFIDIANVQTGRTVHQIPCRAAMNSVEWNPKY 286
>sp|B6GZD3|LIS12_PENRW Nuclear distribution protein nudF 2 OS=Penicillium
rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951
/ Wisconsin 54-1255) OX=500485 GN=nudF-2 PE=3 SV=1
Length=464
Score = 42.8 bits (99), Expect = 0.014, Method: Composition-based stats.
Identities = 23/170 (14%), Positives = 70/170 (41%), Gaps = 16/170 (9%)
Query 45 KDAASCMTVHDKF--LALGTHYGKVYLLDVQGNIT-QKFDVSPVKINQISLDESGEHM-- 99
+D+ +C+ H K+ +A G+ + + D + + + + + + ++ +
Sbjct 114 RDSINCIAFHPKYSLIASGSGDLTIRIWDWEDSTLERTLKGHTMAVCDVDYGDTSSGILL 173
Query 100 GVCSEDGKVQVFGLYSGEEFHETF---DCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER 156
CS D ++++ + +T D + + P S + + + +
Sbjct 174 ASCSSDFTIKLWDTTDDYKNVKTLRGHDHIVSAVRFIP-----SGNLLASASRDMKVILW 228
Query 157 SWMNRWKSAVLHEGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRI 203
+ +N ++ + + G +R + L++ ++M V++++I + Q I
Sbjct 229 NVINGYRVKTIEDHTGWVRDISPSFDGQFLLSTGDDMTVRLWEISASQPI 278
>sp|A9V790|LIS1_MONBE Lissencephaly-1 homolog OS=Monosiga brevicollis
OX=81824 GN=35260 PE=3 SV=1
Length=410
Score = 42.4 bits (98), Expect = 0.014, Method: Composition-based stats.
Identities = 17/78 (22%), Positives = 34/78 (44%), Gaps = 6/78 (8%)
Query 48 ASCMTVHDKF--LALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSE 104
+ + +H F +A + + L D++ GN + +N I+ D G + CS
Sbjct 109 ITAVAIHPSFAVMASASEDASIKLWDMESGNFERSLKGHTNAVNDIAYDREGNRLVSCST 168
Query 105 DGKVQVFGLYSGEEFHET 122
D ++V+ + + F T
Sbjct 169 DMTIKVWNM---DNFTCT 183
>sp|A8XXC7|WDFY2_CAEBR WD repeat and FYVE domain-containing protein
2 OS=Caenorhabditis briggsae OX=6238 GN=wdfy-2 PE=3 SV=2
Length=417
Score = 41.6 bits (96), Expect = 0.024, Method: Composition-based stats.
Identities = 18/92 (20%), Positives = 40/92 (43%), Gaps = 3/92 (3%)
Query 36 SNGVTEILQKDAASCMTVHDKFLALGTHYG---KVYLLDVQGNITQKFDVSPVKINQISL 92
SN V L +++ + M + F+ +G H G + ++D Q N+ K I ++
Sbjct 153 SNKVGSYLLENSCTAMVIDLPFVFVGDHGGHVTVLRIIDNQPNLVSKLSAHTNSITSLTW 212
Query 93 DESGEHMGVCSEDGKVQVFGLYSGEEFHETFD 124
D + + + S D + ++ + G+ +
Sbjct 213 DGNKKVLYSGSSDHLIIMWDIGGGKGEAYELN 244
>sp|Q9VU65|POC1_DROME POC1 centriolar protein homolog OS=Drosophila
melanogaster OX=7227 GN=Poc1 PE=2 SV=1
Length=391
Score = 41.6 bits (96), Expect = 0.025, Method: Composition-based stats.
Identities = 23/110 (21%), Positives = 45/110 (41%), Gaps = 16/110 (15%)
Query 57 FLALGTHYGKVYLLDVQGNIT-QKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYS 115
LA+ ++ + DV G+ Q + V +N ++ SG + S+D +++ L
Sbjct 200 MLAVALGCNRIKIFDVSGSQLLQLYVVHSAPVNDVAFHPSGHFLLSGSDDRTIRILDLLE 259
Query 116 GEEFHETFDCPIKIIAVHPHFV-----RSSCKQFVTGG--KKLLLFERSW 158
PI + H V +F TGG ++LL+++ +
Sbjct 260 --------GRPIYTLTGHTDAVNAVAFSRDGDKFATGGSDRQLLVWQSNL 301
>sp|Q54D08|LST8_DICDI Protein LST8 homolog OS=Dictyostelium discoideum
OX=44689 GN=lst8 PE=1 SV=1
Length=304
Score = 41.2 bits (95), Expect = 0.028, Method: Composition-based stats.
Identities = 42/231 (18%), Positives = 86/231 (37%), Gaps = 17/231 (7%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQ---KFDVSPVKINQISLDESGEHMGVCSEDGKVQV 110
HDK + L +V N FD + + + G+ M SEDG V++
Sbjct 43 HDKLYIAAAGNPQTRLFEVNTNNNSPAMSFDGHKGNVTGVGFQKEGKWMYTGSEDGTVKI 102
Query 111 FGLYSGEEFHETFDC--PIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLH 168
+ L + ++C P+ + +HP+ ++G + + ++ S L
Sbjct 103 WDLKAP-GCQRDYECSAPVNTVVLHPNQAE-----LISGDQNGSIRVWDLISNTCSRELV 156
Query 169 -EGEGNIRS--VKWRGHLIAWANNMG-VKIFDIISKQRITNVPRDDISLRPDMYPCSLCW 224
+GE I S + G L+ +N G ++ + P I +L
Sbjct 157 PDGEVGITSLTISSDGGLVVASNTKGKCFVWRLGEDDTSRFEPLQKIEAHNAPILKTLFS 216
Query 225 KDNVTLIIGWGT-SVKVCSVKERHASEMRDLPSRYV-EIVSQFETEFYISG 273
D L +VK+ + K+ + + + R+V + ++ + ++G
Sbjct 217 PDTKLLATCSADHTVKIWNTKKFNVVQTLNGHQRWVWDCAFSNDSAYLVTG 267
>sp|F6ZT52|POC1B_XENTR POC1 centriolar protein homolog B OS=Xenopus
tropicalis OX=8364 GN=poc1b PE=2 SV=1
Length=470
Score = 41.6 bits (96), Expect = 0.032, Method: Composition-based stats.
Identities = 21/90 (23%), Positives = 36/90 (40%), Gaps = 8/90 (9%)
Query 64 YGKVYLLDVQGN-ITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH-- 120
V + D++ N + Q + V +N +S SG ++ S DG V++ L G +
Sbjct 207 DSTVKVWDIRTNKLLQHYQVHNAGVNSLSFHPSGNYLLTASNDGTVKILDLLEGRLIYTL 266
Query 121 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKK 150
P+ +A S QF +G
Sbjct 267 HGHQGPVLSVAFS-----KSGDQFASGATD 291
>sp|Q10282|GBB_SCHPO Guanine nucleotide-binding protein subunit
beta OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
OX=284812 GN=git5 PE=1 SV=2
Length=305
Score = 40.8 bits (94), Expect = 0.039, Method: Composition-based stats.
Identities = 26/142 (18%), Positives = 53/142 (37%), Gaps = 12/142 (8%)
Query 86 KINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCP---IKIIAVHPHFVRSSCK 142
KI I + G+++ S + + V+ L++ + F+ P I A P S K
Sbjct 23 KIPDIDISTDGKYLLSASTNDVLLVWDLHTSNKVAF-FEAPSVWIMTCAFSP-----STK 76
Query 143 QFVTGG-KKLLLFERSWMNRWKSAVLHEGEGNIRSVKW--RGHLIAWANNMGVKIFDIIS 199
GG + + + L G + K+ GHL+ + + +DI
Sbjct 77 SIAAGGLNNFCVVYDTSVPDADPVELVGHAGFVSCCKYVDDGHLLTGSGDKTCMFWDIEQ 136
Query 200 KQRITNVPRDDISLRPDMYPCS 221
+ I+ + ++ + + S
Sbjct 137 AKAISVLKGHEMDIVSLDFLPS 158
>sp|Q6CB13|MDV1_YARLI Mitochondrial division protein 1 OS=Yarrowia
lipolytica (strain CLIB 122 / E 150) OX=284591 GN=MDV1
PE=3 SV=1
Length=565
Score = 40.8 bits (94), Expect = 0.050, Method: Composition-based stats.
Identities = 29/127 (23%), Positives = 50/127 (39%), Gaps = 12/127 (9%)
Query 48 ASCMTVHDKFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDG 106
+ D LA GT G V L D++ G + + + + D+ H+ S D
Sbjct 418 IGAVQCRDAALATGTADGIVRLWDLRSGQVQRTLQGHTAAVTCLQFDDV--HLATGSRDR 475
Query 107 KVQVFGLYSGEEF-HETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSA 165
V+++ L G F +D PI + + S+ G + +++R+ W
Sbjct 476 SVRIWDLRMGNIFDAFAYDSPITSLDFDNRRIASTN-----GENTVKIYDRAAEKHW--- 527
Query 166 VLHEGEG 172
L GEG
Sbjct 528 SLGRGEG 534
>sp|Q5Z8R1|IPI1_ORYSJ E3 ubiquitin-protein ligase IPI1 OS=Oryza
sativa subsp. japonica OX=39947 GN=IPI1 PE=1 SV=1
Length=455
Score = 40.8 bits (94), Expect = 0.051, Method: Composition-based stats.
Identities = 13/54 (24%), Positives = 18/54 (33%), Gaps = 2/54 (4%)
Query 791 CESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRG 844
C CL ++ + S C H FH +C+ C C RG
Sbjct 51 CSICLDAVVAGGGDR--STARLQCGHEFHLDCIGSAFNAKGVMQCPNCRQIERG 102
>sp|Q8SX81|VPS11_DROME Vacuolar protein sorting-associated protein
11 homolog OS=Drosophila melanogaster OX=7227 GN=Vps11
PE=1 SV=1
Length=830
Score = 41.2 bits (95), Expect = 0.053, Method: Composition-based stats.
Identities = 23/107 (21%), Positives = 41/107 (38%), Gaps = 13/107 (12%)
Query 737 PNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLS 796
P +D L++ + D ++ L E + + + M + + C+ C
Sbjct 684 PIFKDRLLRSIVDSANELKLVEN-----FNEKIKRSRSMLSLYTNNPIEFRNDKCDICRE 738
Query 797 PILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQF-CNICSAKN 842
+ + F C+H FH+ECL S +F C IC +N
Sbjct 739 MLSMQS-------IYFLCQHSFHEECLNYKSTKRQEKFLCIICKTRN 778
>sp|Q93847|WDR52_CAEEL WD repeat-containing protein wdr-5.2 OS=Caenorhabditis
elegans OX=6239 GN=wdr-5.2 PE=4 SV=1
Length=395
Score = 40.5 bits (93), Expect = 0.057, Method: Composition-based stats.
Identities = 14/90 (16%), Positives = 32/90 (36%), Gaps = 4/90 (4%)
Query 50 CMTVHDKFLALGTHYGKVYLL-DVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKV 108
C +A G+ + + GN ++ + + G ++ S DG V
Sbjct 197 CFNPSGTLIASGSFDETIRIWCARNGNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIV 256
Query 109 QVFGLYSG---EEFHETFDCPIKIIAVHPH 135
+++ +G + + PI + P+
Sbjct 257 RIWDSTTGTCVKTLIDEEHPPITHVKFSPN 286
>sp|Q55563|Y163_SYNY3 Uncharacterized WD repeat-containing protein
sll0163 OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803
/ Kazusa) OX=1111708 GN=sll0163 PE=4 SV=1
Length=1693
Score = 40.8 bits (94), Expect = 0.060, Method: Composition-based stats.
Identities = 30/173 (17%), Positives = 61/173 (35%), Gaps = 23/173 (13%)
Query 62 THYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE---- 117
T G YL G + I + G++ S D V+++ + E
Sbjct 1033 TTNGIAYLWSFHGELINVLRGHQEAITALDWSADGQYFATASADHTVKLWQRHGEEVATL 1092
Query 118 EFHETFDCPIKIIAVHPHFVRSSCKQFV--TGGKKLLLFERSWMNRWKSAVLHEGEGN-I 174
HE + ++ + PH QF+ +G R W + L +G + +
Sbjct 1093 RGHEDW---VRSVHFSPH------HQFLVTSGQDN---TARIWNFAGEQLTLCQGHADWV 1140
Query 175 RSVKW--RGHLIAWANNMGV-KIFDIISKQRITNVPRDDISLRPDMYPCSLCW 224
R+ ++ G ++ A+ G +++D+ + I +R + W
Sbjct 1141 RNAEFNCHGQILLTASRDGTARLWDL-EGREIGLCQGHTSWVRNAQFSPDGQW 1192
>sp|P87295|PEP5L_SCHPO Pep5-like zinc finger protein C16A10.03c
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812
GN=SPAC16A10.03c PE=4 SV=2
Length=847
Score = 40.5 bits (93), Expect = 0.074, Method: Composition-based stats.
Identities = 123/848 (15%), Positives = 262/848 (31%), Gaps = 147/848 (17%)
Query 48 ASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGK 107
SC+ K +A+GT G++ +L+ + + + F I Q + + C
Sbjct 31 ISCIGKSTKRIAIGTLDGRIVILNSRLQLIRDFYACEQGIVQQIYITADQSALCCV---- 86
Query 108 VQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMN----RWK 163
+ + F ++ +++P +S L L+E +
Sbjct 87 -----VLDKQNFVY-----LQFWSLNPSKKTNSN-------SPLCLYEHRLYGIPNPPFP 129
Query 164 SAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLC 223
+ L+ S+ + + +AN + +++ + + + + R DI LR +L
Sbjct 130 ATSLY------VSIDIKTVVCGFANGLVIRV-EGDFVRDLGS--RQDIILREKDSITNLI 180
Query 224 WKDNVTLIIGWGTSVKVCSVKER--HASEMRDLPSR--------------------YVEI 261
L + T V V +K +P Y
Sbjct 181 LYSPKKLFVSTTTQVMVYKIKNNTKKVISNHGIPLFCSIQYQGKYIMCAGGSFLSVYTTP 240
Query 262 VSQFETEFYISGLAPLCDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSETCEEISSDA 321
Q + + + G L L +V + E + I+ L + ++
Sbjct 241 DMQLQNTYCVDGTFELLFSSFGLVFVVYTRKNGENGLENNSSIREIKALDVEKRYVLYES 300
Query 322 LTVRGFQENECRDYHLEYSEGE--SLFYIVSPRDVVVAKERDQDDHIDWLLEKKKY---- 375
L + + + + I P D V+ K + + +H D + Y
Sbjct 301 LLEQSYDNIFFNSFDCIFFSSTKVPCQLIRLPSDFVLCKMKGKKEHKDAF-KIANYLGSP 359
Query 376 EEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYK 435
E+ + ++ R ++ Y + +E + +A + L K
Sbjct 360 EDTIRECALAAAGECRQQLNFQDATY--YYIEAIPFSDSAEIIKFYLEKKL--------- 408
Query 436 FKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQ 495
I +L + L I +I + + P ++ +
Sbjct 409 ---IKELTSYLEALSAKGFAFSHEISTLIYLYIKLRKLDKLTEYVSGCPTEISLPILRKY 465
Query 496 AVRDHLKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDK 555
D ++ + L E+Y + A ++ + + ++ D
Sbjct 466 KCLDQMELLGTIRKLPNVCMEVYQEKGDVEKAFNHLQVCNLPELLRTSNSFGIWLFNSDP 525
Query 556 IVLLMDFDSE--KAVDMLLDNEDKISIKKVVE-----ELEDRPELQHVYLHKLFKRDHHK 608
M F E + +++L + +++ ++Q ++L +L K +
Sbjct 526 ----MRFMKEAIRNIEILNSQGKDKELSNILKIVYLGIFSQNVQIQLIFLDELLKSKKSE 581
Query 609 GQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQ-RNFVEETVYLLSRMG-NS 666
LYA + L+ S AL+I + ++ +L +
Sbjct 582 NVLKFIYTRKLYALMQKE-----LQHSNPQNELDALQIIHDSQGLLDYESSILCLQAVSW 636
Query 667 RSALKMIMEELHDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILL 726
+ ++ L KE D L I I P + L+ + D + +
Sbjct 637 KQVTDLLYSHLS--------LKEGQDDSL----IQQIISDPETVKT-LSETYSSEDALHV 683
Query 727 IHRIKEGMEIPN-LRDSLVKILQ----------DYNLQILLREGCKKI------------ 763
+ I N D L KIL+ + L IL+++G
Sbjct 684 LKFFVRERSITNKYEDILYKILEACFMQFRIPIQHVLNILVKDGTLNFCFLKPLLLKWMN 743
Query 764 -------LVADSLSLLKKMHRTQMK--GVLVDEENICESCLSPILPSDAAKPFSVVVFHC 814
D + ++K + + G + D E +C++C + PF V + C
Sbjct 744 DYETRIHQNDDEIQVIKNDIEKKRQLLGTIQDSEKVCDNCEGLLDV-----PF--VSYSC 796
Query 815 RHMFHKEC 822
H+ H++C
Sbjct 797 LHLVHRDC 804
>sp|Q17963|WDR51_CAEEL WD repeat-containing protein wdr-5.1 OS=Caenorhabditis
elegans OX=6239 GN=wdr-5.1 PE=1 SV=1
Length=376
Score = 40.1 bits (92), Expect = 0.075, Method: Composition-based stats.
Identities = 16/108 (15%), Positives = 41/108 (38%), Gaps = 8/108 (7%)
Query 34 RLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQI 90
R++ + + C + + G+ V + DV+ G + ++ +
Sbjct 162 RMTKTLKG--HNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAV 219
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGE---EFHETFDCPIKIIAVHPH 135
S + G + S DG V+++ +G+ + + P+ + P+
Sbjct 220 SFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPN 267
Score = 36.6 bits (83), Expect = 1.0, Method: Composition-based stats.
Identities = 21/156 (13%), Positives = 55/156 (35%), Gaps = 12/156 (8%)
Query 40 TEILQKDAASCMTVHD--KFLALGTHYGKVYLLDV-QGNITQKF-DVSPVKINQISLDES 95
T D S ++ + +A G++ G V + D G + D + + +
Sbjct 208 TLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQCIKTLVDDENPPVAFVKFSPN 267
Query 96 GEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFE 155
G+++ + D ++++ G+ + + +F + K ++G + ++
Sbjct 268 GKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKWIISGSEDCKIYI 327
Query 156 RSWMNRWKSA--------VLHEGEGNIRSVKWRGHL 183
+ R VL ++++ G L
Sbjct 328 WNLQTREIVQCLEGHTQPVLASDCHPVQNIIASGAL 363
>sp|Q59WJ4|PFS2_CANAL Polyadenylation factor subunit 2 OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=PFS2
PE=3 SV=2
Length=543
Score = 40.5 bits (93), Expect = 0.078, Method: Composition-based stats.
Identities = 15/84 (18%), Positives = 28/84 (33%), Gaps = 2/84 (2%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
HD++L G G V N + I+ + C +D ++++
Sbjct 188 HDEWLLSGDQNGTVKYWQPNFNNVNNISAHANGVRDIAFSPNDSKFLTCGDDSAIKIWNF 247
Query 114 YSG--EEFHETFDCPIKIIAVHPH 135
+G E +K HP+
Sbjct 248 NNGKEERTLSGHHWEVKSADWHPN 271
>sp|F4IIK6|LST82_ARATH Non-functional target of rapamycin complex
subunit LST8-2 OS=Arabidopsis thaliana OX=3702 GN=LST8-2
PE=3 SV=1
Length=313
Score = 39.7 bits (91), Expect = 0.088, Method: Composition-based stats.
Identities = 27/121 (22%), Positives = 45/121 (37%), Gaps = 11/121 (9%)
Query 77 TQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFD--CPIKIIAVHP 134
+ F + + +G M SEDG V+++ L E F P+ + +HP
Sbjct 77 VRNFVSHTKNVMAVGFQYTGHMMYSGSEDGSVKIWDLRVRE-CQREFRSVSPVNTVVLHP 135
Query 135 HFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEG-NIRS--VKWRGHLIAWANNMG 191
+ ++G + + S L G IRS V W G ++ AN+ G
Sbjct 136 NQTE-----LISGDQNGNIRVWDLRADLCSCELVPEVGTPIRSLTVMWDGTMVVAANDRG 190
Query 192 V 192
Sbjct 191 T 191
>sp|Q2KJH4|WDR1_BOVIN WD repeat-containing protein 1 OS=Bos taurus
OX=9913 GN=WDR1 PE=2 SV=3
Length=606
Score = 40.1 bits (92), Expect = 0.088, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 37/103 (36%), Gaps = 11/103 (11%)
Query 58 LALGTHYGKVYLLDVQGNIT---QKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL- 113
+A+G G V L + G K + + ++ G + VC V VF +
Sbjct 460 VAVGGADGNVRLYSILGTTLKDEGKLLEAKGPVTDLAFSHDGAFLAVCDASKVVTVFSVA 519
Query 114 --YSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLF 154
YS I +A P + F +GG ++++
Sbjct 520 DGYSENNVFYGHHAKIVCLAWSPD-----NEHFASGGMDMMVY 557
>sp|Q7T394|LIS1A_DANRE Lissencephaly-1 homolog A OS=Danio rerio
OX=7955 GN=pafah1b1a PE=2 SV=3
Length=410
Score = 40.1 bits (92), Expect = 0.091, Method: Composition-based stats.
Identities = 18/114 (16%), Positives = 41/114 (36%), Gaps = 5/114 (4%)
Query 27 EPKLKYERLSNGVTEILQKDAASCMTVHDKF--LALGTHYGKVYLLDVQ-GNITQKFDVS 83
+PK R + + + H F + + + + D + G+ +
Sbjct 90 DPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVIVSASEDATIKVWDHETGDFERTLKGH 149
Query 84 PVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--EFHETFDCPIKIIAVHPH 135
+ IS D +G+ + CS D ++++ E D + +A+ P+
Sbjct 150 TDSVQDISFDHTGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPN 203
>sp|P87177|YB1C_SCHPO Uncharacterized WD repeat-containing protein
C3D6.12 OS=Schizosaccharomyces pombe (strain 972 / ATCC
24843) OX=284812 GN=SPBC3D6.12 PE=1 SV=1
Length=922
Score = 40.1 bits (92), Expect = 0.095, Method: Composition-based stats.
Identities = 18/91 (20%), Positives = 35/91 (38%), Gaps = 1/91 (1%)
Query 23 ESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDV 82
ES E LK +L + + +C+ D+ A+G G + L G + +
Sbjct 44 ESVLEWDLKTGQLLSKWKDSDCSAKVTCIANFDEMYAVGYADGSIRLW-KDGELLITLNG 102
Query 83 SPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
+ + D+ G + S D + V+ +
Sbjct 103 HKSAVTTMDFDKMGTRLASGSMDTDIIVWDI 133
>sp|C3XVT5|LIS1_BRAFL Lissencephaly-1 homolog OS=Branchiostoma
floridae OX=7739 GN=BRAFLDRAFT_59218 PE=3 SV=1
Length=406
Score = 39.7 bits (91), Expect = 0.100, Method: Composition-based stats.
Identities = 22/149 (15%), Positives = 53/149 (36%), Gaps = 15/149 (10%)
Query 1 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKF--L 58
+AEAE++ + S E P +Y + + + H + +
Sbjct 70 LAEAEKEFQSGGPNKKERSPSEWIPRPPA-RYSLSGHRSP-------ITRVLFHPVYSVM 121
Query 59 ALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
+ + + D + G+ + + +S D+ G+ + CS D ++++ + E
Sbjct 122 VSASEDATIKIWDYETGDFERTLKGHTDAVQDVSFDQQGKLLASCSADMTIKLWDFQTFE 181
Query 118 EFH--ETFDCPIKIIAVHP--HFVRSSCK 142
D + + P F+ S+ +
Sbjct 182 NIKTMHGHDHNVSSVHFMPNGDFLISASR 210
>sp|Q00808|HETE1_PODAS Vegetative incompatibility protein HET-E-1
OS=Podospora anserina OX=2587412 GN=HET-E1 PE=4 SV=1
Length=1356
Score = 40.1 bits (92), Expect = 0.10, Method: Composition-based stats.
Identities = 17/87 (20%), Positives = 37/87 (43%), Gaps = 3/87 (3%)
Query 58 LALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSG 116
+A G+ G + + D G TQ + ++ ++ G+ + S DG ++++ SG
Sbjct 1108 VASGSIDGTIKIWDAASGTCTQTLEGHGGWVHSVAFSPDGQRVASGSIDGTIKIWDAASG 1167
Query 117 --EEFHETFDCPIKIIAVHPHFVRSSC 141
+ E ++ +A P R +
Sbjct 1168 TCTQTLEGHGGWVQSVAFSPDGQRVAS 1194
Score = 37.0 bits (84), Expect = 1.1, Method: Composition-based stats.
Identities = 25/169 (15%), Positives = 62/169 (37%), Gaps = 11/169 (7%)
Query 58 LALGTHYGKVYLLD-VQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSG 116
+A G+ + + D V G TQ + + ++ G+ + S DG ++++ SG
Sbjct 1066 VASGSDDHTIKIWDAVSGTCTQTLEGHGDSVWSVAFSPDGQRVASGSIDGTIKIWDAASG 1125
Query 117 --EEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNI 174
+ E + +A P ++ +G + + + L G +
Sbjct 1126 TCTQTLEGHGGWVHSVAFSPD-----GQRVASGSIDGTIKIWDAASGTCTQTLEGHGGWV 1180
Query 175 RSVKWRGH---LIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPC 220
+SV + + + +++ +KI+D S + ++ +
Sbjct 1181 QSVAFSPDGQRVASGSSDKTIKIWDTASGTCTQTLEGHGGWVQSVAFSP 1229
>sp|Q54Y96|SMU1_DICDI WD40 repeat-containing protein smu1 OS=Dictyostelium
discoideum OX=44689 GN=smu1 PE=3 SV=2
Length=530
Score = 40.1 bits (92), Expect = 0.10, Method: Composition-based stats.
Identities = 44/264 (17%), Positives = 95/264 (36%), Gaps = 26/264 (10%)
Query 18 ESEEEE--SEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGN 75
ESEEE+ + + +K+ + T D+ K+L G+ G + + D
Sbjct 206 ESEEEQITTVLDKTIKFNNKNKPETIKFSPDS--------KYLLTGSMDGFIEVWDYNTG 257
Query 76 ITQK---------FDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCP 126
K F + I I+ + GE + S D K++V+ + SG+ P
Sbjct 258 KLSKSLAYQSNDDFMMHDDAILCIAFSKDGEFLATGSLDNKIKVWQIKSGK--CLRKFEP 315
Query 127 IKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGH---L 183
V + Q ++G L + + + + + +
Sbjct 316 AHTNGVTCLQFSRNSTQILSGSFDSSLKIHGLKSGKALKIFRGHQSFVNDCCFNHDEDRV 375
Query 184 IAWANNMGVKIFDI-ISKQRITNVPRDDISLRPDMYPC-SLCWKDNVTLIIGWGTSVKVC 241
I+ +++ +KI+D S T P +++R ++ K+ L++ + + +
Sbjct 376 ISCSSDGKIKIWDAKSSDCLQTITPTSVVTVRDISIRSITILLKNPEFLLVCNSSQISIV 435
Query 242 SVKERHASEMRDLPSRYVEIVSQF 265
S+K + S+ + +V
Sbjct 436 SMKSQTISKTFTSENSKTFLVCTL 459
>sp|P87139|YDM9_SCHPO Uncharacterized RING finger protein C57A7.09
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
OX=284812 GN=SPAC57A7.09 PE=1 SV=1
Length=372
Score = 39.7 bits (91), Expect = 0.11, Method: Composition-based stats.
Identities = 49/238 (21%), Positives = 79/238 (33%), Gaps = 29/238 (12%)
Query 628 LLPFL--RDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIE 685
+L FL + +KALE Q+ F V G++RS + + DK E
Sbjct 141 ILDFLLVQRGKCTYFDKALE-AQRLGFKGVIV------GDNRSPSSFRLHYMVAPDKVDE 193
Query 686 --------FAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIP 737
F LW DL+ +S +P + +G P LL M I
Sbjct 194 SKVHIPSLFVSTSSYNLLWSDLL-HSYRQPLKLYAKPEELGDMFWPFLLCFSPSIIMLIT 252
Query 738 NLRDSLVKILQDYNLQILLREGCKK-----ILVADSLSLLKKMHRTQMKGVLVDEENICE 792
++ K ++ Y + R + I S +++ + G LV +
Sbjct 253 VQALAIRKFIRTYRTKSKTRRFIEDLPSRTISREGFYSEEEEIENSTQNGELVPLMDEST 312
Query 793 S-----CLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGP 845
I K VV C+H FH+ C+ + C C+ + P
Sbjct 313 RRATFGVECVICLESFTKGDKVVALPCKHEFHRPCI-AKWIVDYRHACPTCNTEVPPP 369
>sp|Q15542|TAF5_HUMAN Transcription initiation factor TFIID subunit
5 OS=Homo sapiens OX=9606 GN=TAF5 PE=1 SV=3
Length=800
Score = 40.1 bits (92), Expect = 0.11, Method: Composition-based stats.
Identities = 14/54 (26%), Positives = 22/54 (41%), Gaps = 1/54 (2%)
Query 56 KFLALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKV 108
+FLA G G+V L D+ G + + + + GE + S D V
Sbjct 682 RFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTV 735
Score = 38.1 bits (87), Expect = 0.44, Method: Composition-based stats.
Identities = 16/69 (23%), Positives = 31/69 (45%), Gaps = 3/69 (4%)
Query 48 ASCMTVH--DKFLALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSE 104
+C H ++A G+ V L DV GN + F I+ ++ +G + +
Sbjct 630 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 689
Query 105 DGKVQVFGL 113
DG+V ++ +
Sbjct 690 DGRVLLWDI 698
>sp|Q8C092|TAF5_MOUSE Transcription initiation factor TFIID subunit
5 OS=Mus musculus OX=10090 GN=Taf5 PE=1 SV=1
Length=801
Score = 40.1 bits (92), Expect = 0.11, Method: Composition-based stats.
Identities = 14/54 (26%), Positives = 22/54 (41%), Gaps = 1/54 (2%)
Query 56 KFLALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKV 108
+FLA G G+V L D+ G + + + + GE + S D V
Sbjct 683 RFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTV 736
Score = 37.4 bits (85), Expect = 0.74, Method: Composition-based stats.
Identities = 14/58 (24%), Positives = 28/58 (48%), Gaps = 1/58 (2%)
Query 57 FLALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
++A G+ V L DV GN + F I+ ++ +G + + DG+V ++ +
Sbjct 642 YVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDI 699
>sp|Q20168|COPB2_CAEEL Probable coatomer subunit beta' OS=Caenorhabditis
elegans OX=6239 GN=copb-2 PE=3 SV=3
Length=1000
Score = 40.1 bits (92), Expect = 0.11, Method: Composition-based stats.
Identities = 28/149 (19%), Positives = 58/149 (39%), Gaps = 12/149 (8%)
Query 34 RLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
RL + + D C+ +H + +L + G V++ + + + F+V V +
Sbjct 4 RLDVKRKLLARSDRVKCVDLHPVETWLLAALYNGNVHIWNYETQTLVKSFEVCDVPVRAA 63
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFHE--TFDCPIKIIAVHPHFVRSSCKQFVTGG 148
+ S+D ++VF + E H+ ++ + VHP ++
Sbjct 64 KFVPRKSWVVTGSDDMHIRVFNYNTLERVHQFEAHSDYLRSLVVHPTLPY-----VISSS 118
Query 149 KKLLLFERSWMNRWKSAVLHEGEGNIRSV 177
+L+ W N+W A+ EG+ V
Sbjct 119 DDMLVKMWDWDNKW--AMKQSFEGHTHYV 145
>sp|D3BUN1|LIS1_HETP5 Lissencephaly-1 homolog OS=Heterostelium
pallidum (strain ATCC 26659 / Pp 5 / PN500) OX=670386 GN=PPL_11852
PE=3 SV=1
Length=417
Score = 39.7 bits (91), Expect = 0.11, Method: Composition-based stats.
Identities = 29/159 (18%), Positives = 62/159 (39%), Gaps = 21/159 (13%)
Query 1 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKF--L 58
+++ EE+ +E+ +P + L+ ++ + + H F +
Sbjct 68 VSQLEEELNNGGRGPARRGKEDALPRQP--EKHVLTG------HRNCINAVRFHPLFSVI 119
Query 59 ALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
+ + + D G+ + + I D+SG + CS D ++++
Sbjct 120 VSASEDATMRIWDFDSGDFERTLKGHTNAVQDIDFDKSGNLLASCSADLTIKLWDF---- 175
Query 118 EFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER 156
++FDC IK +H H SC +F+ G +L+ R
Sbjct 176 ---QSFDC-IKT--LHGHDHNVSCVRFLPSGDQLVSSSR 208
>sp|O74184|WAT1_SCHPO Target of rapamycin complex subunit wat1
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812
GN=pop3 PE=1 SV=1
Length=314
Score = 39.3 bits (90), Expect = 0.12, Method: Composition-based stats.
Identities = 20/90 (22%), Positives = 39/90 (43%), Gaps = 5/90 (6%)
Query 50 CMTVHDKFLALGTHYGKVYLLDVQGNI---TQKFDVSPVKINQISLDESGEHMGVCSEDG 106
C++ KFLA V L D+ + F+ + I+ G+ + SEDG
Sbjct 47 CISPDKKFLA-AAGNPHVRLYDINTSSQMPLMTFEGHTNNVTAIAFHCDGKWLATSSEDG 105
Query 107 KVQVFGLYSGE-EFHETFDCPIKIIAVHPH 135
V+V+ + + + + P+ + +HP+
Sbjct 106 TVKVWDMRAPSVQRNYDHKSPVNDLLIHPN 135
Score = 38.1 bits (87), Expect = 0.26, Method: Composition-based stats.
Identities = 25/151 (17%), Positives = 54/151 (36%), Gaps = 15/151 (10%)
Query 28 PKLKYERLSNGVTEILQK-----DAASCMTVH--DKFLALGTHYGKVYLLDVQGNITQKF 80
P ++ ++ L + + + H K+LA + G V + D++ Q+
Sbjct 61 PHVRLYDINTSSQMPLMTFEGHTNNVTAIAFHCDGKWLATSSEDGTVKVWDMRAPSVQRN 120
Query 81 DVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETF---DCPIKIIAVHPHFV 137
+N + + + + C + G+V+ + L HE D P+ I V
Sbjct 121 YDHKSPVNDLLIHPNQGELLSCDQSGRVRAWDLGENSCTHELIPEEDVPMSSITVGSD-- 178
Query 138 RSSCKQFVTGGKKLLLFERSWMNRWKSAVLH 168
+ G K + +N +++L
Sbjct 179 ---GSMLIAGNNKGNCYVWRMLNHQGASLLQ 206
>sp|Q9CWU9|NUP37_MOUSE Nucleoporin Nup37 OS=Mus musculus OX=10090
GN=Nup37 PE=1 SV=2
Length=326
Score = 39.3 bits (90), Expect = 0.12, Method: Composition-based stats.
Identities = 16/106 (15%), Positives = 33/106 (31%), Gaps = 5/106 (5%)
Query 75 NITQKFDVSPVKINQISLD-ESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVH 133
N + + IN + + G+ + S+D +++ L + H P + H
Sbjct 115 NEYKVLEGHSDFINDLVFHPKEGQELASVSDDHTCRIWNLEGKQTAHFLLHSPGMSVCWH 174
Query 134 PHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKW 179
P + K + M + L + + S W
Sbjct 175 PEETFK----LMVAEKNGTIRFYDLMAQQAILSLQSEQTPLMSAHW 216
>sp|O62621|COPB2_DROME Coatomer subunit beta' OS=Drosophila melanogaster
OX=7227 GN=beta'COP PE=2 SV=2
Length=914
Score = 39.7 bits (91), Expect = 0.13, Method: Composition-based stats.
Identities = 37/213 (17%), Positives = 80/213 (38%), Gaps = 20/213 (9%)
Query 45 KDAASCMTVH--DKFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQISLDESGEHMGV 101
D C+ +H + ++ + G V++++ + + F+V V + +
Sbjct 15 SDRVKCVDLHPAEPWMLCALYNGHVHIMNYENQQMVKDFEVCDVPVRSARFVARKNWILT 74
Query 102 CSEDGKVQVFGLYSGEEFH--ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWM 159
S+D +++VF + E+ H E ++ IAVHP + +T +L+ +W
Sbjct 75 GSDDMQIRVFNYNTLEKVHSFEAHSDYLRCIAVHP-----TQPLVLTSSDDMLIKLWNWE 129
Query 160 NRWKSAVLHEGEG-NIRSVKWR---GHLIAWAN-NMGVKIFDIISKQRITNVPRDDISLR 214
W + EG + + + + A A+ + VK++ + S + + +
Sbjct 130 KMWACQRVFEGHTHYVMQIVFNPKDNNTFASASLDRTVKVWQLGSNFANFTLEGHEKGVN 189
Query 215 PDMY-----PCSLCWKDNVTLIIGWGTSVKVCS 242
Y L + L+ W K C
Sbjct 190 CVDYYHGGDKPYLISGADDRLVKIWDYQNKTCV 222
>sp|Q9AYE4|LST8_ORYSJ Target of rapamycin complex subunit LST8
OS=Oryza sativa subsp. japonica OX=39947 GN=LST8 PE=1 SV=1
Length=316
Score = 38.9 bits (89), Expect = 0.14, Method: Composition-based stats.
Identities = 30/145 (21%), Positives = 53/145 (37%), Gaps = 12/145 (8%)
Query 55 DKFLALGTHYGKVYLLDVQGNI---TQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVF 111
DK + L D+ N +D + + G M SEDG V+++
Sbjct 46 DKRFLAAAGNPHIRLFDINSNSNHPVISYDSHTSNVMAVGFHCDGNWMYSGSEDGTVRIW 105
Query 112 GLYSGE-EFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLH-E 169
L + + + + +HP+ K+ ++G + + S L E
Sbjct 106 DLRTATCQREYESRAAVNTVVLHPN-----QKELISGDQNGNIRVWDLAANSCSCELVPE 160
Query 170 GEGNIRS--VKWRGHLIAWANNMGV 192
+ +RS V W G ++ ANN G
Sbjct 161 VDTAVRSLTVMWDGSMVVAANNRGT 185
>sp|Q9BVA0|KTNB1_HUMAN Katanin p80 WD40 repeat-containing subunit
B1 OS=Homo sapiens OX=9606 GN=KATNB1 PE=1 SV=1
Length=655
Score = 39.3 bits (90), Expect = 0.15, Method: Composition-based stats.
Identities = 22/193 (11%), Positives = 63/193 (33%), Gaps = 21/193 (11%)
Query 55 DKFLALGTHYGKVYLLDVQG-NITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
++ + G+ G + + D++ I + I + GE + S+D + L
Sbjct 75 EELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNI---KL 131
Query 114 YSGEEFHETFDC-----PIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLH 168
+ F ++ + P K + + +
Sbjct 132 WDIRRKGCVFRYRGHSQAVRCLRFSPD-----GKWLASAADDHTVKLWDLTAGKMMSEFP 186
Query 169 EGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWK 225
G + V++ + L + +++ ++ +D+ Q ++ + + +R ++ C
Sbjct 187 GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCL 246
Query 226 ----DNVTLIIGW 234
+ + GW
Sbjct 247 YSGCQDSLRVYGW 259
Score = 35.5 bits (80), Expect = 2.5, Method: Composition-based stats.
Identities = 18/103 (17%), Positives = 44/103 (43%), Gaps = 9/103 (9%)
Query 40 TEILQKDAASCMTVH--DKFLALGTHYGKVYLLDV--QGNITQKFDVSPVKINQISLDES 95
T + K + H +F+A G+ + L D+ +G + + + + +
Sbjct 100 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFR-YRGHSQAVRCLRFSPD 158
Query 96 GEHMGVCSEDGKVQVFGLYSGEEFHETF---DCPIKIIAVHPH 135
G+ + ++D V+++ L +G + F P+ ++ HP+
Sbjct 159 GKWLASAADDHTVKLWDLTAG-KMMSEFPGHTGPVNVVEFHPN 200
>sp|Q8BG40|KTNB1_MOUSE Katanin p80 WD40 repeat-containing subunit
B1 OS=Mus musculus OX=10090 GN=Katnb1 PE=1 SV=1
Length=658
Score = 39.3 bits (90), Expect = 0.15, Method: Composition-based stats.
Identities = 22/193 (11%), Positives = 63/193 (33%), Gaps = 21/193 (11%)
Query 55 DKFLALGTHYGKVYLLDVQG-NITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
++ + G+ G + + D++ I + I + GE + S+D + L
Sbjct 75 EELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNI---KL 131
Query 114 YSGEEFHETFDC-----PIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLH 168
+ F ++ + P K + + +
Sbjct 132 WDIRRKGCVFRYRGHSQAVRCLRFSPD-----GKWLASAADDHTVKLWDLTAGKMMSEFP 186
Query 169 EGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWK 225
G + V++ + L + +++ ++ +D+ Q ++ + + +R ++ C
Sbjct 187 GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCL 246
Query 226 ----DNVTLIIGW 234
+ + GW
Sbjct 247 YSGCQDSLRVYGW 259
Score = 35.5 bits (80), Expect = 2.5, Method: Composition-based stats.
Identities = 18/103 (17%), Positives = 44/103 (43%), Gaps = 9/103 (9%)
Query 40 TEILQKDAASCMTVH--DKFLALGTHYGKVYLLDV--QGNITQKFDVSPVKINQISLDES 95
T + K + H +F+A G+ + L D+ +G + + + + +
Sbjct 100 TLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFR-YRGHSQAVRCLRFSPD 158
Query 96 GEHMGVCSEDGKVQVFGLYSGEEFHETF---DCPIKIIAVHPH 135
G+ + ++D V+++ L +G + F P+ ++ HP+
Sbjct 159 GKWLASAADDHTVKLWDLTAG-KMMSEFPGHTGPVNVVEFHPN 200
>sp|A0A1L8GLK3|RFW3L_XENLA E3 ubiquitin-protein ligase rfwd3.L
OS=Xenopus laevis OX=8355 GN=rfwd3.L PE=1 SV=1
Length=751
Score = 39.7 bits (91), Expect = 0.15, Method: Composition-based stats.
Identities = 13/58 (22%), Positives = 22/58 (38%), Gaps = 4/58 (7%)
Query 786 DEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNR 843
DE + C C P + + + C H+F C+ + A C C+ K +
Sbjct 259 DEGDTCAICFEPWTNAGQHR---LSALRCGHLFGFTCIE-RWLKGGASKCPQCNKKAK 312
>sp|Q4V7Y7|KTNB1_XENLA Katanin p80 WD40 repeat-containing subunit
B1 OS=Xenopus laevis OX=8355 GN=katnb1 PE=1 SV=1
Length=655
Score = 39.3 bits (90), Expect = 0.16, Method: Composition-based stats.
Identities = 23/102 (23%), Positives = 45/102 (44%), Gaps = 7/102 (7%)
Query 40 TEILQKDAASCMTVH--DKFLALGTHYGKVYLLDV--QGNITQKFDVSPVKINQISLDES 95
T + K S + H +F+A G+ + L DV +G + + + + +
Sbjct 100 TLMGHKANVSSLDFHPYGEFVASGSLDTNIKLWDVRRKGCVFR-YKGHTQAVRCLRFSPD 158
Query 96 GEHMGVCSEDGKVQVFGLYSGEEFHE--TFDCPIKIIAVHPH 135
G+ + S+D V+++ L +G+ E P+ II HP+
Sbjct 159 GKWLASASDDHSVKLWDLTAGKMMAELSEHKGPVNIIEFHPN 200
>sp|Q9SUS5|RHA1B_ARATH E3 ubiquitin-protein ligase RHA1B OS=Arabidopsis
thaliana OX=3702 GN=RHA1B PE=2 SV=1
Length=157
Score = 37.4 bits (85), Expect = 0.17, Method: Composition-based stats.
Identities = 22/88 (25%), Positives = 37/88 (42%), Gaps = 7/88 (8%)
Query 757 REGCKKILVADSLSLLKKMHRTQMKG-VLVDEENICESCLSPILPSDAAKPFSVVVFHCR 815
R ++ ++ S +L ++ +L D E+ C CLS + D + C
Sbjct 50 RSDPTRLALSTSATLANELIPVVRFSDLLTDPEDCCTVCLSDFVSDDKIRQLP----KCG 105
Query 816 HMFHKECLPMPSMNSAAQFCNICSAKNR 843
H+FH CL ++ C IC +NR
Sbjct 106 HVFHHRCLDRWIVDCNKITCPIC--RNR 131
>sp|A0A974CYQ5|RFW3S_XENLA E3 ubiquitin-protein ligase rfwd3.S
OS=Xenopus laevis OX=8355 GN=rfwd3.S PE=1 SV=1
Length=750
Score = 39.3 bits (90), Expect = 0.18, Method: Composition-based stats.
Identities = 13/58 (22%), Positives = 22/58 (38%), Gaps = 4/58 (7%)
Query 786 DEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNR 843
DE + C C P + + + C H+F C+ + A C C+ K +
Sbjct 258 DEGDTCAICFEPWTNAGQHR---LSALRCGHLFGFTCIE-RWLKGGAAKCPQCNKKAK 311
>sp|Q6ZJX0|FIE2_ORYSJ Polycomb group protein FIE1 OS=Oryza sativa
subsp. japonica OX=39947 GN=FIE2 PE=1 SV=1
Length=376
Score = 38.9 bits (89), Expect = 0.18, Method: Composition-based stats.
Identities = 28/96 (29%), Positives = 41/96 (43%), Gaps = 14/96 (15%)
Query 27 EPKLKYERLSNGVTEILQKDAAS---------CMTVHDKFLALGTHYGKVYLLDVQGN-- 75
EPK K + G +ILQK H LA+G GKV++ +VQ +
Sbjct 270 EPKTKEQSPGEGSIDILQKYPVPECDIWFIKFSCDFHFNQLAIGNREGKVFVWEVQSSPP 329
Query 76 -ITQKFDVSPVK--INQISLDESGEHMGVCSEDGKV 108
+T + K I Q ++ G + CSEDG +
Sbjct 330 VLTARLTNPQCKSAIRQTAVSFDGSTILACSEDGSI 365
>sp|P87053|POF1_SCHPO F-box/WD repeat-containing protein pof1
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812
GN=pof1 PE=1 SV=1
Length=605
Score = 39.3 bits (90), Expect = 0.19, Method: Composition-based stats.
Identities = 17/90 (19%), Positives = 34/90 (38%), Gaps = 4/90 (4%)
Query 46 DAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSED 105
D+ C+T L G+ V L G +N + + + S+D
Sbjct 354 DSVLCLTFDSTLLVSGSADCTVKLWHFSGGKRITLRGHTGPVNSVRIIRDRGLVLSGSDD 413
Query 106 GKVQVFGLYSGEEFHETFDC---PIKIIAV 132
++++ L + H TF P++ +A+
Sbjct 414 STIKIWSLETNTCLH-TFSAHIGPVQSLAL 442
>sp|O62471|QUI1_CAEEL Protein qui-1 OS=Caenorhabditis elegans
OX=6239 GN=qui-1 PE=1 SV=2
Length=1592
Score = 39.3 bits (90), Expect = 0.19, Method: Composition-based stats.
Identities = 49/288 (17%), Positives = 96/288 (33%), Gaps = 52/288 (18%)
Query 46 DAASCM--TVHDKFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVC 102
D +C+ +V ++ G G + +LD Q G + ++ + ++ I + M C
Sbjct 1208 DPITCIRYSVDSQYCISGNQAGCILILDAQNGGVVRELFMHSSEVLSI-MSLVHNKMISC 1266
Query 103 SEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERS---WM 159
GK+ ++ L+ ++ E +K P FV + + V L + W
Sbjct 1267 DIQGKMVIWELFGDDDTPEMVATGVKP----PIFVPPTGRIMV---GHCSLSNKEMKIWA 1319
Query 160 NR------WKSAVLHEGEGNIRSVKWR---GHLIAWAN-NMGVKIFDIISKQRITNVPRD 209
++ + H E I G+ IA + +M +KI+ I +
Sbjct 1320 FPEEGPPVTRAKLSHSDE--ITCFATSPKGGNFIATGSRDMSLKIWQIDKGFLTQVLVGH 1377
Query 210 DISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFETEF 269
+ + C + L++ K+ + ++V T
Sbjct 1378 ENVVTC------CCISFDERLVVSGARDEKIIVWNVQSG-----------DMVCTVNTTA 1420
Query 270 YISGLAPLCDQLVVL-----SYVKEISEKTER----EYCARPRLDIIQ 308
I+ L+ D VV +V+ S R RP +I
Sbjct 1421 AITSLSMTGDSTVVFSTTEDGWVETWSTTKGRLLSTFNAHRPIKKLIN 1468
>sp|Q9UUG8|TUP12_SCHPO Transcriptional repressor tup12 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=tup12
PE=1 SV=2
Length=598
Score = 39.3 bits (90), Expect = 0.19, Method: Composition-based stats.
Identities = 21/143 (15%), Positives = 43/143 (30%), Gaps = 27/143 (19%)
Query 22 EESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFD 81
+ E KL T + D +F+A G+ + + G + ++
Sbjct 416 DVEAGEQKLILHTDDGVTTVMFSPDG--------QFIAAGSLDKVIRIWTSSGTLVEQLH 467
Query 82 VSPVKINQISLDESGEHMGVCSEDGKV----------QVFGLYSGEEFH-ETF---DCPI 127
+ ++ G+++ S D + +Y +TF I
Sbjct 468 GHEESVYSVAFSPDGKYLVSGSLDNTIKLWELQCVSNVAPSMYKEGGICKQTFTGHKDFI 527
Query 128 KIIAVHPHFVRSSCKQFVTGGKK 150
+ V P K ++G K
Sbjct 528 LSVTVSPD-----GKWIISGSKD 545
>sp|O74319|TAF73_SCHPO Transcription initiation factor TFIID subunit
taf73 OS=Schizosaccharomyces pombe (strain 972 / ATCC
24843) OX=284812 GN=taf73 PE=1 SV=1
Length=642
Score = 38.9 bits (89), Expect = 0.21, Method: Composition-based stats.
Identities = 37/276 (13%), Positives = 86/276 (31%), Gaps = 40/276 (14%)
Query 47 AASCMTVHD--KFLALGTHYGKVYLLDVQGN-------------ITQKFDVSPVKINQIS 91
A +C D ALG ++L N + +S
Sbjct 351 AVNCAAFSDDASMFALGCADSSIHLYSSTNNGPQPLVGSQNEPLQKSSLIGHTRPVFGVS 410
Query 92 LDESGEHMGVCSEDGKVQVFGLYSGEEFHE--TFDCPIKIIAVHP--HFVRSSCKQFVTG 147
+ E + CSEDG +++ + + + PI + P ++ ++
Sbjct 411 ISPQKEFILSCSEDGFTRLWSKDTKSTIVKYAGHNAPIWDVQFSPFGYYFATASH----- 465
Query 148 GKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRIT 204
+ L++ + V H+ + + V + + L +++ +++D+ + +
Sbjct 466 DQTARLWDVEHAAPLRVFVGHQND--VDCVSFHPNAAYLATGSSDHTTRMWDVRTGGTV- 522
Query 205 NVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQ 264
V S + L + + V + +S ++ IV
Sbjct 523 RVFNAHHSPVSALC------MSADGLSLASADESGIIKVWDLRSSNQHVSFVKHSSIVYS 576
Query 265 FETEF----YISGLAPLCDQLVVLSYVKEISEKTER 296
+ +SG A L+Y +S+ +
Sbjct 577 LSFSYDNKILVSGGADTDVNFWDLTYRNNLSDGEQS 612
>sp|Q8NFH4|NUP37_HUMAN Nucleoporin Nup37 OS=Homo sapiens OX=9606
GN=NUP37 PE=1 SV=1
Length=326
Score = 38.5 bits (88), Expect = 0.22, Method: Composition-based stats.
Identities = 16/106 (15%), Positives = 34/106 (32%), Gaps = 5/106 (5%)
Query 75 NITQKFDVSPVKINQISLD-ESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVH 133
N + + IN + D + G+ + S+D +++ L + H P + H
Sbjct 115 NEYKVLEGHTDFINGLVFDPKEGQEIASVSDDHTCRIWNLEGVQTAHFVLHSPGMSVCWH 174
Query 134 PHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKW 179
P + K + + + L + + S W
Sbjct 175 PEETFK----LMVAEKNGTIRFYDLLAQQAILSLESEQVPLMSAHW 216
>sp|Q6BVZ3|PFS2_DEBHA Polyadenylation factor subunit 2 OS=Debaryomyces
hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394
/ JCM 1990 / NBRC 0083 / IGC 2968) OX=284592 GN=PFS2 PE=3 SV=2
Length=504
Score = 38.9 bits (89), Expect = 0.24, Method: Composition-based stats.
Identities = 33/168 (20%), Positives = 63/168 (38%), Gaps = 16/168 (10%)
Query 55 DKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
D++L G G + N + I I+ + CS+D ++++
Sbjct 176 DEWLLSGDQSGVIKYWQTNFNNVNIINGHSDGIRDIAFSPNDSKFLTCSDDSTMKIWNFN 235
Query 115 SGEEFHETF--DCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAV--LHEG 170
+G+E +K HP+ V+G K L+ + W R S V LH
Sbjct 236 NGQEERSLVGHHWDVKSADWHPNLG-----LIVSGSKDNLI--KLWDPRASSCVSTLHGF 288
Query 171 EGNIRSVKWRGH-----LIAWANNMGVKIFDIISKQRITNVPRDDISL 213
+ I K++ L + + + +IFD+ + + I + + L
Sbjct 289 KHTITKTKFQPTGTKRLLASVSRDKSCRIFDLRTMKDILVIRDHETDL 336
>sp|Q10322|DMA1_SCHPO Probable E3 ubiquitin-protein ligase dma1
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812
GN=dma1 PE=1 SV=1
Length=267
Score = 38.1 bits (87), Expect = 0.25, Method: Composition-based stats.
Identities = 30/135 (22%), Positives = 56/135 (41%), Gaps = 19/135 (14%)
Query 717 IGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLREGC--KKILVADSLSL--- 771
GT ++ + L K P + ++++ DY + C ++ + +S +
Sbjct 107 SGTFLNHVRLSPPSKTSKPYPISNNDILQLGADYRGGHEVNYRCVRARVELNNSWKIKLS 166
Query 772 ---LKKMHRTQMKGVLVDEEN---ICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPM 825
L + R Q + E+ C CL P+LP A + V C H +H +C+
Sbjct 167 PYNLNEFKRMQELVLCGSSESGPPECCICLMPVLPCQA-----LFVAPCSHSYHYKCIR- 220
Query 826 PSMNSAAQF--CNIC 838
P++N + + C IC
Sbjct 221 PTLNESHPYFSCFIC 235
>sp|P73595|Y1410_SYNY3 Uncharacterized WD repeat-containing protein
slr1410 OS=Synechocystis sp. (strain ATCC 27184 / PCC
6803 / Kazusa) OX=1111708 GN=slr1410 PE=4 SV=1
Length=334
Score = 38.5 bits (88), Expect = 0.25, Method: Composition-based stats.
Identities = 21/118 (18%), Positives = 39/118 (33%), Gaps = 9/118 (8%)
Query 7 QETGSLEESTDESEEEESEE-EPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYG 65
+ G + S D + E S EP R +A+ G
Sbjct 152 DDMGVVTSSDDGTIEGWSNIKEPLFTVTRPGVSRNMDFNAQT--------NLIAVTQDIG 203
Query 66 KVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETF 123
++ LL+ G + + + ++N + + G+ + DG +VF L E
Sbjct 204 EITLLNPAGKVVRIIETDQGRLNDVDFSQDGKLLVTAGFDGTARVFNLDGQEILKIDV 261
Score = 35.8 bits (81), Expect = 1.8, Method: Composition-based stats.
Identities = 10/53 (19%), Positives = 20/53 (38%), Gaps = 0/53 (0%)
Query 56 KFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKV 108
K + + G + DVQGN+ + + + + S+DG +
Sbjct 113 KAIITAGYNGVARIWDVQGNVLGEILGHTSAVTDVVFLSDDMGVVTSSDDGTI 165
>sp|Q5AGM0|HIR2_CANAL Protein HIR2 OS=Candida albicans (strain
SC5314 / ATCC MYA-2876) OX=237561 GN=HIR2 PE=3 SV=2
Length=1017
Score = 38.9 bits (89), Expect = 0.26, Method: Composition-based stats.
Identities = 21/109 (19%), Positives = 42/109 (39%), Gaps = 9/109 (8%)
Query 22 EESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFD 81
E+ E + ++ + + S ++ +A T+ GKVYL DV + Q+
Sbjct 108 EQPETKQLFPFKSIETSEVNPVVDLTISA---DNRLIAWSTNNGKVYLYDVVKDTFQELT 164
Query 82 V----SPVKINQISLDESGEHMGVCSEDGKVQVF--GLYSGEEFHETFD 124
P+ I+ D S ++ +D ++ VF + T+
Sbjct 165 SICHEKPIIQRSIAFDPSNNYLITVGDDTQINVFQYSYEKDDTSTTTYK 213
>sp|Q0J3D9|COPA3_ORYSJ Coatomer subunit alpha-3 OS=Oryza sativa
subsp. japonica OX=39947 GN=Os09g0127800 PE=2 SV=1
Length=1218
Score = 38.9 bits (89), Expect = 0.26, Method: Composition-based stats.
Identities = 29/156 (19%), Positives = 60/156 (38%), Gaps = 13/156 (8%)
Query 63 HYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE---E 118
H G + + D + G + +FD + + + +D K++V+ +
Sbjct 29 HSGVIQMWDYRMGTLLDRFDEHDGPVRGVHFHATQPLFVSGGDDYKIKVWNYKTHRCLFT 88
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVK 178
H D I+ + H + V+ + +W +R AVL +
Sbjct 89 LHGHLDY-IRTVQFHHEYPW-----IVSASDDQTIRIWNWQSRTCVAVLTGHNHYVMCAS 142
Query 179 WR--GHLIAWAN-NMGVKIFDIISKQRITNVPRDDI 211
+ L+ A+ + V+++DI + ++ T P DDI
Sbjct 143 FHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 178
>sp|Q9AUR8|COPA1_ORYSJ Coatomer subunit alpha-1 OS=Oryza sativa
subsp. japonica OX=39947 GN=Os03g0711400 PE=2 SV=1
Length=1218
Score = 38.9 bits (89), Expect = 0.26, Method: Composition-based stats.
Identities = 29/156 (19%), Positives = 60/156 (38%), Gaps = 13/156 (8%)
Query 63 HYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE---E 118
H G + + D + G + +FD + + + +D K++V+ +
Sbjct 29 HSGVIQMWDYRMGTLLDRFDEHDGPVRGVHFHATQPLFVSGGDDYKIKVWNYKTHRCLFT 88
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVK 178
H D I+ + H + V+ + +W +R AVL +
Sbjct 89 LHGHLDY-IRTVQFHHEYPW-----IVSASDDQTIRIWNWQSRTCVAVLTGHNHYVMCAS 142
Query 179 WR--GHLIAWAN-NMGVKIFDIISKQRITNVPRDDI 211
+ L+ A+ + V+++DI + ++ T P DDI
Sbjct 143 FHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 178
>sp|Q9ZT50|RHA2A_ARATH E3 ubiquitin-protein ligase RHA2A OS=Arabidopsis
thaliana OX=3702 GN=RHA2A PE=1 SV=1
Length=155
Score = 37.0 bits (84), Expect = 0.27, Method: Composition-based stats.
Identities = 26/118 (22%), Positives = 52/118 (44%), Gaps = 15/118 (13%)
Query 714 LNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQDYNLQILLRE------GCKKILVAD 767
L+++ + P++L+ + I +LR L+++ N + + + I++AD
Sbjct 7 LSDVSSDSIPLMLLSLLAVF--INHLRSFLLRLTSKSNPNLPVDDVSIASGLANIIVLAD 64
Query 768 SLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPM 825
LSL ++ + + C CLS + + + CRH+FHK+CL
Sbjct 65 QLSL-NRLFSYRCGDGGGGGSD-CVVCLSKLKEGEEVRK-----LECRHVFHKKCLEG 115
>sp|O88342|WDR1_MOUSE WD repeat-containing protein 1 OS=Mus musculus
OX=10090 GN=Wdr1 PE=1 SV=3
Length=606
Score = 38.5 bits (88), Expect = 0.28, Method: Composition-based stats.
Identities = 22/97 (23%), Positives = 42/97 (43%), Gaps = 10/97 (10%)
Query 47 AASCMTVH----DKFLALGTHYGKVYLLDVQGNITQKFDV--SPVKINQISLDESGEHMG 100
+ C+TVH ++ G+H G + D + F ++++++++ES E +
Sbjct 322 SIQCLTVHRNGGKSYIYSGSHDGHINYWDSETGENDSFSGKGHTNQVSRMTVNES-EQLV 380
Query 101 VCSEDGKVQVFGLYSGE---EFHETFDCPIKIIAVHP 134
CS D V+ L + + D K +AV P
Sbjct 381 SCSMDDTVRYTNLTLRDYSGQGVVKLDVQPKCVAVGP 417
>sp|O93277|WDR1_CHICK WD repeat-containing protein 1 OS=Gallus
gallus OX=9031 GN=WDR1 PE=2 SV=1
Length=609
Score = 38.5 bits (88), Expect = 0.28, Method: Composition-based stats.
Identities = 28/135 (21%), Positives = 48/135 (36%), Gaps = 25/135 (19%)
Query 40 TEILQKDAASCMTVHD--------------KFLALGTHYGKVYLLDVQGNITQKFDVS-- 83
+L KD C + D +A+G G V L +QG + D +
Sbjct 430 QIVLMKDKKKCFAIDDLGYEPEAVAVHPGGGSVAVGGTDGNVRLYSIQGTSLKSDDKTLE 489
Query 84 -PVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETF---DCPIKIIAVHPHFVRS 139
+ ++ G + VC + V VF + G H F + IA P
Sbjct 490 AKGPVTDLAYSHDGAFLAVCDANKVVTVFSVPDGYVEHNVFYGHHAKVVCIAWSPD---- 545
Query 140 SCKQFVTGGKKLLLF 154
+ F +GG ++++
Sbjct 546 -NEHFASGGMDMMVY 559
>sp|A8NEG8|LIS1_COPC7 Nuclear distribution protein PAC1 OS=Coprinopsis
cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC
9003) OX=240176 GN=PAC1 PE=3 SV=3
Length=434
Score = 38.1 bits (87), Expect = 0.30, Method: Composition-based stats.
Identities = 25/183 (14%), Positives = 73/183 (40%), Gaps = 18/183 (10%)
Query 49 SCMTVHDKF--LALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSED 105
+ + H ++ LA + V + D + G + +N + D G + CS D
Sbjct 112 TSIAFHPQYSILASASEDTTVKIWDWETGEFERTLKGHTKPVNDLDFDHKGHLLVTCSSD 171
Query 106 GKVQVFGLYSGEEFHETF---DCPIKIIAVHP--HFVRSSCKQFVTGGKKLLLFERSWMN 160
++++ + + +TF D + + P + S+ + + + +F+ + +
Sbjct 172 LFIKIWDSQNEWKNTKTFVGHDHAVSAVRFMPGDQLIVSASR-----DRTIRVFDVASTH 226
Query 161 RWKSAVLHEGEGNIRSV--KWRGHLIAWAN-NMGVKIFDIISKQRITNVPRDDISLRPDM 217
+ ++ H +R V G ++A + + V+++D ++ + + + + +
Sbjct 227 QVRTLSGHSE--WVRCVIPSADGTMLASGSKDQTVRLWDPLTGEPKSELRGHENDVEAVA 284
Query 218 YPC 220
+
Sbjct 285 FAP 287
Score = 36.2 bits (82), Expect = 1.3, Method: Composition-based stats.
Identities = 22/85 (26%), Positives = 37/85 (44%), Gaps = 9/85 (11%)
Query 54 HDKFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFG 112
H FLA G V L D Q G + + + ++ SG+++ S+D V+V+
Sbjct 308 HGLFLASGARDKTVKLWDTQTGQMIRNLAGHDNWVRALAFHPSGKYLLSSSDDKTVRVWE 367
Query 113 LYSGEEFHETFDCPIKIIAVHPHFV 137
L + ++I+ H HFV
Sbjct 368 LST--------GRCLRIVEAHSHFV 384
>sp|Q90ZL4|LIS1_XENLA Lissencephaly-1 homolog OS=Xenopus laevis
OX=8355 GN=pafah1b1 PE=2 SV=3
Length=410
Score = 38.1 bits (87), Expect = 0.31, Method: Composition-based stats.
Identities = 31/199 (16%), Positives = 69/199 (35%), Gaps = 27/199 (14%)
Query 27 EPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHY--GKVYLLDVQ-GNITQKFDVS 83
+PK R + + + H F + T + + D + G+ +
Sbjct 90 DPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVTASEDATIKVWDYETGDFERTLKGH 149
Query 84 PVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--EFHETFDCPIKIIAVHPHFVRSSC 141
+ IS D SG+ + CS D ++++ E D + +A+ P+
Sbjct 150 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECLRTMHGHDHNVSSVAIMPN------ 203
Query 142 KQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRSVKW--------RGHLIA-WANNMG 191
G ++ R + W+ + + +W G LIA +N+
Sbjct 204 ------GDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQT 257
Query 192 VKIFDIISKQRITNVPRDD 210
V+++ + +K+ + +
Sbjct 258 VRVWVVATKECKAELREHE 276
>sp|Q7ZUV2|KTNB1_DANRE Katanin p80 WD40 repeat-containing subunit
B1 OS=Danio rerio OX=7955 GN=katnb1 PE=2 SV=1
Length=694
Score = 38.5 bits (88), Expect = 0.31, Method: Composition-based stats.
Identities = 20/102 (20%), Positives = 47/102 (46%), Gaps = 7/102 (7%)
Query 40 TEILQKDAASCMTVH--DKFLALGTHYGKVYLLDV--QGNITQKFDVSPVKINQISLDES 95
T + K + S + H ++LA G+ + L DV +G + + + + ++
Sbjct 100 TLMGHKASISSLDFHPMGEYLASGSVDSNIKLWDVRRKGCVFR-YKGHTQAVRCLAFSPD 158
Query 96 GEHMGVCSEDGKVQVFGLYSGEEFHE--TFDCPIKIIAVHPH 135
G+ + S+D V+++ L +G+ E + + ++ HP+
Sbjct 159 GKWLASASDDSTVKLWDLIAGKMITEFTSHTSAVNVVQFHPN 200
>sp|Q6NZH4|LIS1_XENTR Lissencephaly-1 homolog OS=Xenopus tropicalis
OX=8364 GN=pafah1b1 PE=2 SV=3
Length=410
Score = 38.1 bits (87), Expect = 0.31, Method: Composition-based stats.
Identities = 31/199 (16%), Positives = 69/199 (35%), Gaps = 27/199 (14%)
Query 27 EPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHY--GKVYLLDVQ-GNITQKFDVS 83
+PK R + + + H F + T + + D + G+ +
Sbjct 90 DPKEWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVTASEDATIKVWDYETGDFERTLKGH 149
Query 84 PVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--EFHETFDCPIKIIAVHPHFVRSSC 141
+ IS D SG+ + CS D ++++ E D + +A+ P+
Sbjct 150 TDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPN------ 203
Query 142 KQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRSVKW--------RGHLIA-WANNMG 191
G ++ R + W+ + + +W G LIA +N+
Sbjct 204 ------GDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQT 257
Query 192 VKIFDIISKQRITNVPRDD 210
V+++ + +K+ + +
Sbjct 258 VRVWVVATKECKAELREHE 276
>sp|Q54DS8|SEC13_DICDI Protein SEC13 homolog OS=Dictyostelium
discoideum OX=44689 GN=sec13 PE=1 SV=1
Length=301
Score = 37.8 bits (86), Expect = 0.32, Method: Composition-based stats.
Identities = 36/199 (18%), Positives = 76/199 (38%), Gaps = 30/199 (15%)
Query 87 INQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDC-----PIKIIAV-HPHFVRSS 140
++ D G+ + CS D +++F + GE D P+ +A HP F +
Sbjct 14 VHDAQFDYYGKFLATCSSDKMIKIFDV-GGENPQHLVDLRGHEGPVWQVAWAHPKFGKIL 72
Query 141 CKQFVTGGKKLLLFERSWMNRWKSAVLHEG-EGNIRSVKW----RGHLIAWANNMGV--- 192
+ +K+++++ N W + G E ++ S+ W G +A A++ G
Sbjct 73 AS--ASYDRKVIVWKEVGNNSWSIIHQYAGHELSVNSISWAPHEFGLSLACASSDGSVTI 130
Query 193 -----KIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNV-------TLIIGWGTS-VK 239
+++ K +++ + + +S P P SL N ++ G + +K
Sbjct 131 HNYNNNVWEAPQKIQVSQIGVNSVSWSPAAIPTSLVNSANTIIPAPIKRIVTGSCDNLIK 190
Query 240 VCSVKERHASEMRDLPSRY 258
+ E + L
Sbjct 191 IFKNVEDKWILDKQLEDHK 209
>sp|Q6CP71|PFS2_KLULA Polyadenylation factor subunit 2 OS=Kluyveromyces
lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 /
NBRC 1267 / NRRL Y-1140 / WM37) OX=284590 GN=PFS2 PE=3 SV=1
Length=452
Score = 38.1 bits (87), Expect = 0.32, Method: Composition-based stats.
Identities = 29/200 (15%), Positives = 80/200 (40%), Gaps = 20/200 (10%)
Query 56 KFLALGTHYGKVYLLDVQG-NITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQV---- 110
+ L + T+ G+ L N + ++ +G+ M S DG++++
Sbjct 94 RRLVVATYNGEFSLWSGSSFNFESIMQAHDSAVTVMTYSHTGDWMVSGSADGELKIWQPN 153
Query 111 -FGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHE 169
+ ++ H ++ I+ P + ++FV+ +L ++ N + VL
Sbjct 154 FNMVKVMDQAHMEC---VREISFSP-----TDQKFVSCSDDNVLKIWNFSNGQQERVLSG 205
Query 170 GEGNIRSVKWR---GHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKD 226
+++S W G +++ + + +K +D S ++ + ++ + +
Sbjct 206 HHWDVKSCDWHPKMGLIVSGSKDNLIKFWDPRSGSCVSTMLGFKHTIISTKFQPK---QG 262
Query 227 NVTLIIGWGTSVKVCSVKER 246
N+ +I + KV ++++
Sbjct 263 NLLSVISKDKTCKVYDIRQQ 282
>sp|Q9H6Y7|RN167_HUMAN E3 ubiquitin-protein ligase RNF167 OS=Homo
sapiens OX=9606 GN=RNF167 PE=1 SV=1
Length=350
Score = 38.1 bits (87), Expect = 0.33, Method: Composition-based stats.
Identities = 18/62 (29%), Positives = 27/62 (44%), Gaps = 7/62 (11%)
Query 786 DEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAK-NRG 844
D+ ++C CL D + V C H +H C+ P + + C IC +RG
Sbjct 225 DQYDVCAICLDEYEDGDKLR-----VLPCAHAYHSRCVD-PWLTQTRKTCPICKQPVHRG 278
Query 845 PG 846
PG
Sbjct 279 PG 280
>sp|O82239|RFI2_ARATH E3 ubiquitin-protein ligase RFI2 OS=Arabidopsis
thaliana OX=3702 GN=RFI2 PE=1 SV=2
Length=358
Score = 38.1 bits (87), Expect = 0.33, Method: Composition-based stats.
Identities = 14/57 (25%), Positives = 18/57 (32%), Gaps = 3/57 (5%)
Query 788 ENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRG 844
E C CL +L C H FH +C+ A C C +G
Sbjct 35 EVSCSICLESVLDDGTRSK---AKLQCGHQFHLDCIGSAFNMKGAMQCPNCRNVEKG 88
>sp|P73594|Y1409_SYNY3 WD repeat-containing protein slr1409 OS=Synechocystis
sp. (strain ATCC 27184 / PCC 6803 / Kazusa) OX=1111708
GN=slr1409 PE=1 SV=1
Length=326
Score = 38.1 bits (87), Expect = 0.33, Method: Composition-based stats.
Identities = 15/82 (18%), Positives = 34/82 (41%), Gaps = 1/82 (1%)
Query 55 DKFLALGT-HYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
D+ + + T + G + L ++QG + ++ + + + CS+DG+ ++F
Sbjct 101 DRQILITTGYDGTIRLWNLQGELLEEQQPHRAAVADAIFSPDSQIIVTCSDDGQTKIFTR 160
Query 114 YSGEEFHETFDCPIKIIAVHPH 135
E + +A HP
Sbjct 161 QGQEIASVLKSGTARNLAYHPQ 182
>sp|B7PS00|LIS1_IXOSC Lissencephaly-1 homolog OS=Ixodes scapularis
OX=6945 GN=IscW_ISCW007420 PE=3 SV=2
Length=411
Score = 38.1 bits (87), Expect = 0.36, Method: Composition-based stats.
Identities = 34/235 (14%), Positives = 78/235 (33%), Gaps = 31/235 (13%)
Query 1 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDKF--L 58
+AEAE++ S E P + + + + H + +
Sbjct 70 LAEAEKEYISGTPSREKRSPTEWIPRPP--------ERSALLGHRAPITRVLFHPVYSVV 121
Query 59 ALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
+ + + D + G+ + + I+ D +G+ + CS D ++++ S E
Sbjct 122 VSASEDASIKVWDYETGDFERTIKGHTDSVQDIAFDHTGQFLASCSADMTIKLWDFKSYE 181
Query 118 EFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRS 176
+H H S F+ G ++ R + W+ A +
Sbjct 182 CLR----------TMHGHDHNVSSVCFLPSGDHVVSCSRDKSIKMWEVATGYCVRTFTGH 231
Query 177 VKW--------RGHLIA-WANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSL 222
W G L+A +N+ V+++ + +K+ + D + + +
Sbjct 232 RDWVRMVRVNSDGSLLASCSNDQTVRVWVVGTKECKLELREHDHVVECVAWAPAH 286
>sp|Q93794|SEL10_CAEEL F-box/WD repeat-containing protein sel-10
OS=Caenorhabditis elegans OX=6239 GN=sel-10 PE=1 SV=3
Length=587
Score = 38.1 bits (87), Expect = 0.37, Method: Composition-based stats.
Identities = 37/227 (16%), Positives = 84/227 (37%), Gaps = 19/227 (8%)
Query 47 AASCMTVHDKFLALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSED 105
+CM +HD L G+ + + + +G + + + + G ++ S D
Sbjct 258 VITCMQIHDDVLVTGSDDNTLKVWCIDKGEVMYTLVGHTGGVWTSQISQCGRYIVSGSTD 317
Query 106 GKVQVFGLYSGEEFH--ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWK 163
V+V+ G H + ++ +A+ + VTG + L +
Sbjct 318 RTVKVWSTVDGSLLHTLQGHTSTVRCMAM-------AGSILVTGSRDTTLRVWDVESGRH 370
Query 164 SAVLHEGEGNIRSVKWRG-HLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSL 222
A LH +R V++ G +++ + VKI++ + + I + + + SL
Sbjct 371 LATLHGHHAAVRCVQFDGTTVVSGGYDFTVKIWNAHTGRCIRTLTGHNNRV------YSL 424
Query 223 CWKDNVTLIIGWG--TSVKVCSVKERHASEMRDLPSRYVEIVSQFET 267
++ +++ TS++V E L + + S +
Sbjct 425 LFESERSIVCSGSLDTSIRVWDFTRPEGQECVALLQGHTSLTSGMQL 471
>sp|Q9DC22|DCAF6_MOUSE DDB1- and CUL4-associated factor 6 OS=Mus
musculus OX=10090 GN=Dcaf6 PE=1 SV=1
Length=876
Score = 38.1 bits (87), Expect = 0.39, Method: Composition-based stats.
Identities = 10/41 (24%), Positives = 21/41 (51%), Gaps = 0/41 (0%)
Query 80 FDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH 120
+V +N I +++GE++ S+D K+ + YS +
Sbjct 47 LNVHDGCVNTICWNDTGEYILSGSDDTKLVISNPYSRKVLT 87
>sp|Q9W7F2|WDR1A_XENLA WD repeat-containing protein 1-A OS=Xenopus
laevis OX=8355 GN=wdr1-a PE=2 SV=2
Length=607
Score = 38.1 bits (87), Expect = 0.39, Method: Composition-based stats.
Identities = 20/104 (19%), Positives = 42/104 (40%), Gaps = 13/104 (13%)
Query 58 LALGTHYGKVYLLDVQGNITQKFDVSPVK----INQISLDESGEHMGVCSEDGKVQVFGL 113
+A+G GKV+L +QGN + + + + ++ G + V + V VF +
Sbjct 460 VAVGGADGKVHLYSIQGNSLKD-EGKTLPAKGAVTDLAYSHDGAFLAVTDANKVVTVFSV 518
Query 114 ---YSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLF 154
YS + + +A P + F + G ++++
Sbjct 519 ADGYSEKNSYYGHHAKALSVAWSPD-----NEHFASSGMDMMVY 557
>sp|Q28D01|WDR26_XENTR WD repeat-containing protein 26 OS=Xenopus
tropicalis OX=8364 GN=wdr26 PE=2 SV=2
Length=614
Score = 38.1 bits (87), Expect = 0.39, Method: Composition-based stats.
Identities = 28/169 (17%), Positives = 67/169 (40%), Gaps = 30/169 (18%)
Query 58 LALGTHYGKVYLLD-----VQGNITQKFDVSPVKINQISLDESGEHMGVCSED--GKVQV 110
LA G+ V + Q + + + ++ ++ ++ C D ++ +
Sbjct 323 LATGSKDTTVIIWQVDPDTHQLKLLKTLEGHAYGVSYLAWSPDDNYLIACGPDDCSELWL 382
Query 111 FGLYSGE---EFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVL 167
+ + +GE + ++ + + +A +P K+FVTGG++ ++
Sbjct 383 WNVQTGELRTKMSQSHEDSLTSVAWNPD-----GKRFVTGGQRGQFYQ------------ 425
Query 168 HEGEGNIRSVKWRGHLI--AWANNMGVKIFDIISKQRITNVPRDDISLR 214
+ +GN+ W G + W + G + + QRI +D++ R
Sbjct 426 CDLDGNLLD-SWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTDR 473
>sp|Q99M63|SMU1_RAT WD40 repeat-containing protein SMU1 OS=Rattus
norvegicus OX=10116 GN=Smu1 PE=2 SV=1
Length=513
Score = 38.1 bits (87), Expect = 0.41, Method: Composition-based stats.
Identities = 9/46 (20%), Positives = 22/46 (48%), Gaps = 0/46 (0%)
Query 72 VQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
G ++F +N+ + + G ++ S DG V+++ + + E
Sbjct 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTE 382
>sp|Q3UKJ7|SMU1_MOUSE WD40 repeat-containing protein SMU1 OS=Mus
musculus OX=10090 GN=Smu1 PE=2 SV=2
Length=513
Score = 38.1 bits (87), Expect = 0.41, Method: Composition-based stats.
Identities = 9/46 (20%), Positives = 22/46 (48%), Gaps = 0/46 (0%)
Query 72 VQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
G ++F +N+ + + G ++ S DG V+++ + + E
Sbjct 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTE 382
>sp|Q2TAY7|SMU1_HUMAN WD40 repeat-containing protein SMU1 OS=Homo
sapiens OX=9606 GN=SMU1 PE=1 SV=2
Length=513
Score = 38.1 bits (87), Expect = 0.41, Method: Composition-based stats.
Identities = 9/46 (20%), Positives = 22/46 (48%), Gaps = 0/46 (0%)
Query 72 VQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
G ++F +N+ + + G ++ S DG V+++ + + E
Sbjct 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTE 382
>sp|Q76B40|SMU1_CRIGR WD40 repeat-containing protein SMU1 OS=Cricetulus
griseus OX=10029 GN=SMU1 PE=1 SV=1
Length=513
Score = 38.1 bits (87), Expect = 0.41, Method: Composition-based stats.
Identities = 9/46 (20%), Positives = 22/46 (48%), Gaps = 0/46 (0%)
Query 72 VQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
G ++F +N+ + + G ++ S DG V+++ + + E
Sbjct 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTE 382
>sp|Q2TBS9|SMU1_BOVIN WD40 repeat-containing protein SMU1 OS=Bos
taurus OX=9913 GN=SMU1 PE=2 SV=1
Length=513
Score = 38.1 bits (87), Expect = 0.41, Method: Composition-based stats.
Identities = 9/46 (20%), Positives = 22/46 (48%), Gaps = 0/46 (0%)
Query 72 VQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
G ++F +N+ + + G ++ S DG V+++ + + E
Sbjct 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTE 382
>sp|Q6P4J8|SMU1_XENTR WD40 repeat-containing protein SMU1 OS=Xenopus
tropicalis OX=8364 GN=smu1 PE=2 SV=1
Length=513
Score = 38.1 bits (87), Expect = 0.41, Method: Composition-based stats.
Identities = 9/46 (20%), Positives = 22/46 (48%), Gaps = 0/46 (0%)
Query 72 VQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
G ++F +N+ + + G ++ S DG V+++ + + E
Sbjct 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTE 382
>sp|Q6NRT3|SMU1_XENLA WD40 repeat-containing protein SMU1 OS=Xenopus
laevis OX=8355 GN=smu1 PE=2 SV=1
Length=513
Score = 38.1 bits (87), Expect = 0.41, Method: Composition-based stats.
Identities = 9/46 (20%), Positives = 22/46 (48%), Gaps = 0/46 (0%)
Query 72 VQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
G ++F +N+ + + G ++ S DG V+++ + + E
Sbjct 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTE 382
>sp|O61585|KTNB1_STRPU Katanin p80 WD40 repeat-containing subunit
B1 OS=Strongylocentrotus purpuratus OX=7668 GN=KATNB1 PE=1
SV=1
Length=690
Score = 38.1 bits (87), Expect = 0.42, Method: Composition-based stats.
Identities = 27/118 (23%), Positives = 49/118 (42%), Gaps = 15/118 (13%)
Query 25 EEEPKLKYERLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDV--QGNITQKF 80
+ EP L+ +++ CM H +F+A G+ V L DV +G I +
Sbjct 87 DLEPAKIVRTLTG------HRNSIRCMDFHPFGEFVASGSTDTNVKLWDVRRKGCIY-TY 139
Query 81 DVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCP---IKIIAVHPH 135
++N I G+ + SED ++++ L G + + F + I HP+
Sbjct 140 KGHSDQVNMIKFSPDGKWLVTASEDTTIKLWDLTMG-KLFQEFKNHTGGVTGIEFHPN 196
>sp|Q7PS24|CIAO1_ANOGA Probable cytosolic iron-sulfur protein
assembly protein Ciao1 OS=Anopheles gambiae OX=7165 GN=Ciao1
PE=3 SV=3
Length=341
Score = 37.8 bits (86), Expect = 0.43, Method: Composition-based stats.
Identities = 13/50 (26%), Positives = 24/50 (48%), Gaps = 0/50 (0%)
Query 69 LLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEE 118
L D + + + + + IS D +G+ + CSED V+V+ Y +
Sbjct 184 LADSEWEMLEPLESHSSTVWSISFDATGQRLASCSEDTTVKVWQQYGPDN 233
>sp|Q5R9B8|DCAF6_PONAB DDB1- and CUL4-associated factor 6 OS=Pongo
abelii OX=9601 GN=DCAF6 PE=2 SV=2
Length=860
Score = 38.1 bits (87), Expect = 0.43, Method: Composition-based stats.
Identities = 10/41 (24%), Positives = 21/41 (51%), Gaps = 0/41 (0%)
Query 80 FDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH 120
+V +N I +++GE++ S+D K+ + YS +
Sbjct 47 LNVHDGCVNTICWNDTGEYILSGSDDTKLVISNPYSRKVLT 87
>sp|Q58WW2|DCAF6_HUMAN DDB1- and CUL4-associated factor 6 OS=Homo
sapiens OX=9606 GN=DCAF6 PE=1 SV=1
Length=860
Score = 38.1 bits (87), Expect = 0.43, Method: Composition-based stats.
Identities = 10/41 (24%), Positives = 21/41 (51%), Gaps = 0/41 (0%)
Query 80 FDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH 120
+V +N I +++GE++ S+D K+ + YS +
Sbjct 47 LNVHDGCVNTICWNDTGEYILSGSDDTKLVISNPYSRKVLT 87
>sp|Q75AV4|PFS2_EREGS Polyadenylation factor subunit 2 OS=Eremothecium
gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923
/ NRRL Y-1056) OX=284811 GN=PSF2 PE=3 SV=1
Length=449
Score = 37.8 bits (86), Expect = 0.44, Method: Composition-based stats.
Identities = 36/168 (21%), Positives = 63/168 (38%), Gaps = 24/168 (14%)
Query 58 LALGTHYGKVYLLDVQGNITQKFD-VSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSG 116
L G G + + N+ + D + IS S + CS+D ++++ +G
Sbjct 136 LISGDADGTIKIWQPNFNMVKVLDRAHTECMRDISFSYSDQKFVTCSDDNVLKIWNFSNG 195
Query 117 --EEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSW---MNRWKSAVLHEGE 171
E +K HP V+G K L+ + W R S +L
Sbjct 196 QQERVLSGHHWDVKSCDWHPKMG-----LIVSGSKDNLI--KLWDPRTGRNVSTIL---- 244
Query 172 GNIRSV------KWRGHLIAWAN-NMGVKIFDIISKQRITNVPRDDIS 212
G +V +G+L+A + + +KI+D+ R RDD+
Sbjct 245 GLKHTVIKTKFQPTQGNLLAVVSKDKSIKIYDMRQHMRELQTIRDDMD 292
>sp|Q6NV31|WDR82_DANRE WD repeat-containing protein 82 OS=Danio
rerio OX=7955 GN=wdr82 PE=2 SV=1
Length=313
Score = 37.4 bits (85), Expect = 0.46, Method: Composition-based stats.
Identities = 27/122 (22%), Positives = 48/122 (39%), Gaps = 15/122 (12%)
Query 29 KLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLD-VQGNITQKF---DVSP 84
KL+YER D K + + T+ G + +LD +G + F + S
Sbjct 188 KLQYERTCEWTGLKFSNDG--------KLILVSTNGGTLRVLDAFKGAVLHSFGGYNNSK 239
Query 85 VKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDC---PIKIIAVHPHFVRSSC 141
I + S + + + SEDGK+ V+ SG + P+ + +P F+ +
Sbjct 240 GVILEASFTPDSQFIMIGSEDGKIHVWNAESGMKVALLDGKHTGPVTCLQFNPKFMTFAS 299
Query 142 KQ 143
Sbjct 300 AC 301
>sp|Q8W4Q5|RIN3_ARATH E3 ubiquitin protein ligase RIN3 OS=Arabidopsis
thaliana OX=3702 GN=RIN3 PE=1 SV=2
Length=577
Score = 37.8 bits (86), Expect = 0.47, Method: Composition-based stats.
Identities = 32/181 (18%), Positives = 61/181 (34%), Gaps = 27/181 (15%)
Query 668 SALKMIMEELH----DVDKAIEFAKEQDDGEL-WEDLILYSIDKPPFITGLLNNIGTHVD 722
L M + L D ++ + L W+ L+ ++ + L+ +G ++
Sbjct 215 QLLDMWINHLAVKNSDCQRSKFYDSMTAGSLLEWKGLLNRNLGFFLDMATLVMALGHYLH 274
Query 723 PILLIHR---IKEGMEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQ 779
L + + + N+R L IL+ I LR + A + +++
Sbjct 275 IWWLHGMAFHLVDAVLFLNIRALLSSILKRIKGYIKLRVALGALHAALLDATSEELR--- 331
Query 780 MKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMN--SAAQFCNI 837
D ++ C C P+ + HC H+FH CL + C
Sbjct 332 ------DYDDECAICREPMAKA--------KRLHCNHLFHLGCLRSWLDQGLNEVYSCPT 377
Query 838 C 838
C
Sbjct 378 C 378
>sp|Q8K450|SPG16_MOUSE Sperm-associated antigen 16 protein OS=Mus
musculus OX=10090 GN=Spag16 PE=1 SV=1
Length=639
Score = 37.8 bits (86), Expect = 0.47, Method: Composition-based stats.
Identities = 11/53 (21%), Positives = 24/53 (45%), Gaps = 0/53 (0%)
Query 56 KFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKV 108
+ LA + G ++LLD++ K +++ + GE++ DG +
Sbjct 583 RVLAQASANGIIHLLDLKSGQIHKLVGHESEVHSVVFSHLGENLYSGGSDGTI 635
>sp|O75083|WDR1_HUMAN WD repeat-containing protein 1 OS=Homo sapiens
OX=9606 GN=WDR1 PE=1 SV=4
Length=606
Score = 37.8 bits (86), Expect = 0.47, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 37/103 (36%), Gaps = 11/103 (11%)
Query 58 LALGTHYGKVYLLDVQGNIT---QKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL- 113
+A+G G V L + G K + + ++ G + VC V VF +
Sbjct 460 VAIGGVDGNVRLYSILGTTLKDEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVTVFSVA 519
Query 114 --YSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLF 154
YS I +A P + F +GG ++++
Sbjct 520 DGYSENNVFYGHHAKIVCLAWSPD-----NEHFASGGMDMMVY 557
>sp|Q9Y7K5|YGI3_SCHPO Uncharacterized WD repeat-containing protein
C2A9.03 OS=Schizosaccharomyces pombe (strain 972 / ATCC
24843) OX=284812 GN=SPBC2A9.03 PE=4 SV=2
Length=426
Score = 37.8 bits (86), Expect = 0.49, Method: Composition-based stats.
Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
Query 41 EILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMG 100
ILQK A SC+ + LGT YG+ + + + +S IN I L + +
Sbjct 176 NILQKKAISCLDTTNAVGCLGTLYGQYCIFNFKNGSFSTRKLSDDSINHIQLFSEKKFIL 235
Query 101 VCSEDGKVQV 110
C DG V V
Sbjct 236 GC-NDGAVYV 244
>sp|Q8I0F4|LIS1_DICDI Lissencephaly-1 homolog OS=Dictyostelium
discoideum OX=44689 GN=lis1 PE=1 SV=1
Length=419
Score = 37.4 bits (85), Expect = 0.51, Method: Composition-based stats.
Identities = 21/115 (18%), Positives = 46/115 (40%), Gaps = 13/115 (11%)
Query 45 KDAASCMTVHDKF--LALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGV 101
++ + + H F + + + + D + G + + I D++G +
Sbjct 106 RNCINSVKFHPSFSLMVSASEDATIKVWDFESGEFERTLKGHTNAVQDIDFDKTGNLLAS 165
Query 102 CSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER 156
CS D ++++ +T+DC + +H H SC +F G +L+ R
Sbjct 166 CSADLTIKLWDF-------QTYDC---VKTLHGHDHNVSCVRFTPSGDQLISSSR 210
>sp|Q6ZQA0|NBEL2_MOUSE Neurobeachin-like protein 2 OS=Mus musculus
OX=10090 GN=Nbeal2 PE=1 SV=2
Length=2742
Score = 38.1 bits (87), Expect = 0.51, Method: Composition-based stats.
Identities = 23/90 (26%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query 34 RLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVS-PVKINQISL 92
RL VT Q A + V + F+ LGT +++L + + V ++ +S+
Sbjct 2627 RLRASVTLTEQPTALT---VAEDFVLLGTAQCSLHILHLNKLRPAVPPLPMKVPVHSVSV 2683
Query 93 DESGEHMGVCSEDGKVQVFGLYSGEEFHET 122
+ H+ V EDGK+ V G E +
Sbjct 2684 TKERSHVLVGLEDGKLIVVGAGQPSEVRSS 2713
>sp|Q8VE80|THOC3_MOUSE THO complex subunit 3 OS=Mus musculus OX=10090
GN=Thoc3 PE=2 SV=1
Length=351
Score = 37.4 bits (85), Expect = 0.52, Method: Composition-based stats.
Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query 56 KFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
K+ A G+ V L DV + + F + +S G+ + SED + + +
Sbjct 237 KYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVE 296
Query 115 SGEEFHE-TFDCPIKIIAVHP 134
+G++ E + P +A HP
Sbjct 297 TGDKLWEVQCESPTFTVAWHP 317
>sp|Q96J01|THOC3_HUMAN THO complex subunit 3 OS=Homo sapiens OX=9606
GN=THOC3 PE=1 SV=1
Length=351
Score = 37.4 bits (85), Expect = 0.52, Method: Composition-based stats.
Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query 56 KFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
K+ A G+ V L DV + + F + +S G+ + SED + + +
Sbjct 237 KYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVE 296
Query 115 SGEEFHE-TFDCPIKIIAVHP 134
+G++ E + P +A HP
Sbjct 297 TGDKLWEVQCESPTFTVAWHP 317
>sp|Q29RH4|THOC3_BOVIN THO complex subunit 3 OS=Bos taurus OX=9913
GN=THOC3 PE=2 SV=1
Length=351
Score = 37.4 bits (85), Expect = 0.52, Method: Composition-based stats.
Identities = 19/81 (23%), Positives = 35/81 (43%), Gaps = 2/81 (2%)
Query 56 KFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
K+ A G+ V L DV + + F + +S G+ + SED + + +
Sbjct 237 KYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVE 296
Query 115 SGEEFHE-TFDCPIKIIAVHP 134
+G++ E + P +A HP
Sbjct 297 TGDKLWEVQCESPTFTVAWHP 317
>sp|Q5RFQ3|PWP2_PONAB Periodic tryptophan protein 2 homolog OS=Pongo
abelii OX=9601 GN=PWP2 PE=2 SV=1
Length=918
Score = 37.8 bits (86), Expect = 0.53, Method: Composition-based stats.
Identities = 30/138 (22%), Positives = 54/138 (39%), Gaps = 18/138 (13%)
Query 23 ESEEEPKLKYERLSNGVTEILQKDA----ASCMTVHDK--FLALGTHYGKVYLLDV-QGN 75
E E+ K+KY RL+ K+ + H K L G G +L ++ + N
Sbjct 262 EEEKTGKVKYSRLA---KYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFN 318
Query 76 ITQKFDVSPVKINQISLDESGEHMG-VCSEDGKVQVFGLYSGEEFHETFDCP--IKIIAV 132
+ +S I ++++ SG+ + CS G++ V+ S + + +A
Sbjct 319 LIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAY 378
Query 133 HPHFVRSSCKQFVTGGKK 150
P + VTGG
Sbjct 379 SPD-----GQYIVTGGDD 391
>sp|Q15269|PWP2_HUMAN Periodic tryptophan protein 2 homolog OS=Homo
sapiens OX=9606 GN=PWP2 PE=1 SV=2
Length=919
Score = 37.8 bits (86), Expect = 0.53, Method: Composition-based stats.
Identities = 30/138 (22%), Positives = 54/138 (39%), Gaps = 18/138 (13%)
Query 23 ESEEEPKLKYERLSNGVTEILQKDA----ASCMTVHDK--FLALGTHYGKVYLLDV-QGN 75
E E+ K+KY RL+ K+ + H K L G G +L ++ + N
Sbjct 265 EEEKTGKVKYSRLA---KYFFNKEGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFN 321
Query 76 ITQKFDVSPVKINQISLDESGEHMG-VCSEDGKVQVFGLYSGEEFHETFDCP--IKIIAV 132
+ +S I ++++ SG+ + CS G++ V+ S + + +A
Sbjct 322 LIHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAY 381
Query 133 HPHFVRSSCKQFVTGGKK 150
P + VTGG
Sbjct 382 SPD-----GQYIVTGGDD 394
>sp|Q9PTR5|LIS1_CHICK Lissencephaly-1 homolog OS=Gallus gallus
OX=9031 GN=PAFAH1B1 PE=2 SV=3
Length=410
Score = 37.4 bits (85), Expect = 0.54, Method: Composition-based stats.
Identities = 24/162 (15%), Positives = 59/162 (36%), Gaps = 25/162 (15%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + + IS D +G+ + CS D ++++ E
Sbjct 127 SEDATIKVWDYETGDFERTLKGHTDSVQDISFDHTGKLLASCSADMTIKLWDFQGFECIR 186
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRSV 177
D + +A+ P+ G ++ R + W+ + +
Sbjct 187 TMHGHDHNVSSVAIMPN------------GDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 234
Query 178 KW--------RGHLIA-WANNMGVKIFDIISKQRITNVPRDD 210
+W G LIA +N+ V+++ + +K+ + +
Sbjct 235 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>sp|Q8N4F7|RN175_HUMAN RING finger protein 175 OS=Homo sapiens
OX=9606 GN=RNF175 PE=1 SV=2
Length=328
Score = 37.4 bits (85), Expect = 0.54, Method: Composition-based stats.
Identities = 15/78 (19%), Positives = 27/78 (35%), Gaps = 2/78 (3%)
Query 766 ADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPF--SVVVFHCRHMFHKECL 823
+D ++ + +NIC C I+ + + C H+FH+ C+
Sbjct 202 SDYMASTIGFYSVSRLPTRSLSDNICAVCGQKIIVELDEEGLIENTYQLSCNHVFHEFCI 261
Query 824 PMPSMNSAAQFCNICSAK 841
+ Q C C K
Sbjct 262 RGWCIVGKKQTCPYCKEK 279
>sp|C5FP68|SCONB_ARTOC Probable E3 ubiquitin ligase complex SCF
subunit sconB OS=Arthroderma otae (strain ATCC MYA-4605 /
CBS 113480) OX=554155 GN=sconB PE=3 SV=1
Length=674
Score = 37.8 bits (86), Expect = 0.55, Method: Composition-based stats.
Identities = 16/71 (23%), Positives = 31/71 (44%), Gaps = 0/71 (0%)
Query 50 CMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQ 109
C+ LA G+ + + + Q TQ +N + LD + + S+D V+
Sbjct 423 CLHFDSTTLASGSKDNTIKIWNFQDKSTQILRGHTDWVNAVKLDTASRTVFSASDDLTVR 482
Query 110 VFGLYSGEEFH 120
++ L +G+ H
Sbjct 483 IWDLDTGKCIH 493
>sp|A9BE38|MQO_PROM4 Probable malate:quinone oxidoreductase OS=Prochlorococcus
marinus (strain MIT 9211) OX=93059 GN=mqo PE=3
SV=1
Length=500
Score = 37.4 bits (85), Expect = 0.57, Method: Composition-based stats.
Identities = 20/78 (26%), Positives = 30/78 (38%), Gaps = 5/78 (6%)
Query 8 ETGSLEESTDESEEEESEEEPKLKYE-----RLSNGVTEILQKDAASCMTVHDKFLALGT 62
+ G+L + +S EE +L E R ++ K + V KF+ LG
Sbjct 187 DFGALTRAYFDSLEESGSVHIRLSTEVIDIQRFGQDPWKLFLKSDLNSYCVEGKFVFLGA 246
Query 63 HYGKVYLLDVQGNITQKF 80
G + LL G KF
Sbjct 247 GGGALSLLQKSGIPEGKF 264
>sp|Q91WQ5|TAF5L_MOUSE TAF5-like RNA polymerase II p300/CBP-associated
factor-associated factor 65 kDa subunit 5L OS=Mus musculus
OX=10090 GN=Taf5l PE=2 SV=1
Length=589
Score = 37.8 bits (86), Expect = 0.57, Method: Composition-based stats.
Identities = 23/93 (25%), Positives = 39/93 (42%), Gaps = 5/93 (5%)
Query 48 ASCMTVH--DKFLALGTHYGKVYLLD-VQGNITQKFDVSPVKINQISLDESGEHMGVCSE 104
C+ H +LA G+ V L QGN + F + +S +G+++ E
Sbjct 429 VDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLSFSPNGKYLASAGE 488
Query 105 DGKVQVFGLYSGEEFHETFDC--PIKIIAVHPH 135
D +++++ L SG F E I +A P
Sbjct 489 DQRLKLWDLASGTLFKELRGHTDSITSLAFSPD 521
>sp|A3LNW3|SEC13_PICST Protein transport protein SEC13 OS=Scheffersomyces
stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063
/ NRRL Y-11545) OX=322104 GN=SEC13 PE=3 SV=2
Length=302
Score = 37.0 bits (84), Expect = 0.58, Method: Composition-based stats.
Identities = 29/140 (21%), Positives = 52/140 (37%), Gaps = 13/140 (9%)
Query 82 VSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH-----ETFDCPIKIIAV-HPH 135
I+ LD G+ + CS D + +F + E + D P+ ++ HP
Sbjct 7 AHNDLIHDAVLDYYGKRLATCSSDKSINIFDIDGTESYKLVSTLTGHDGPVWQVSWAHPK 66
Query 136 FVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEG-EGNIRSVKWRGH-----LIAWANN 189
F G K L+ E+ +W H + ++ SV W H L+ +++
Sbjct 67 FGSILASCSFDG-KALIWKEQPETQQWSIIAEHSVHQASVNSVSWAPHELGAVLLCASSD 125
Query 190 MGVKIFDIISKQRITNVPRD 209
V + D ++V D
Sbjct 126 GKVSVVDFNDDGTTSHVVFD 145
>sp|B5X3Z6|LIS1A_SALSA Lissencephaly-1 homolog A OS=Salmo salar
OX=8030 GN=pafah1b1-1 PE=2 SV=1
Length=410
Score = 37.4 bits (85), Expect = 0.60, Method: Composition-based stats.
Identities = 13/77 (17%), Positives = 31/77 (40%), Gaps = 3/77 (4%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + + IS D +G+ + CS D ++++ E
Sbjct 127 SEDATIKVWDYETGDFERTLKGHTDSVQDISFDHTGKLLASCSADMTIKLWDFQGFECIR 186
Query 119 FHETFDCPIKIIAVHPH 135
D + +A+ P+
Sbjct 187 TMHGHDHNVSSVAIMPN 203
>sp|Q9LY41|ATL4_ARATH E3 ubiquitin-protein ligase ATL4 OS=Arabidopsis
thaliana OX=3702 GN=ATL4 PE=1 SV=1
Length=334
Score = 37.0 bits (84), Expect = 0.60, Method: Composition-based stats.
Identities = 15/67 (22%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query 774 KMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQ 833
K + ++ + C CLS P D + + C H FH +C+ + +++ Q
Sbjct 101 KFSSVTRRSSSMNSGD-CAVCLSKFEPEDQLRLLPL----CCHAFHADCIDIWLVSN--Q 153
Query 834 FCNICSA 840
C +C +
Sbjct 154 TCPLCRS 160
>sp|Q09715|TUP11_SCHPO Transcriptional repressor tup11 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=tup11
PE=1 SV=1
Length=614
Score = 37.4 bits (85), Expect = 0.60, Method: Composition-based stats.
Identities = 16/103 (16%), Positives = 39/103 (38%), Gaps = 14/103 (14%)
Query 47 AASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDG 106
A ++ +D+F+A+G+ + + V G + ++ + + I+ + S D
Sbjct 447 TAIAISPNDQFIAVGSLDQIIRVWSVSGTLVERLEGHKESVYSIAFSPDSSILLSGSLDK 506
Query 107 KVQVFGLYSGEEFHETFDCP--------------IKIIAVHPH 135
++V+ L + + P + +AV P
Sbjct 507 TIKVWELQATRSVGLSAIKPEGICKATYTGHTDFVLSVAVSPD 549
>sp|Q5IS43|LIS1_PANTR Platelet-activating factor acetylhydrolase
IB subunit alpha OS=Pan troglodytes OX=9598 GN=PAFAH1B1 PE=2
SV=3
Length=410
Score = 37.4 bits (85), Expect = 0.62, Method: Composition-based stats.
Identities = 25/162 (15%), Positives = 59/162 (36%), Gaps = 25/162 (15%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + + IS D SG+ + CS D ++++ E
Sbjct 127 SEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIR 186
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRSV 177
D + +A+ P+ G ++ R + W+ + +
Sbjct 187 TMHGHDHNVSSVAIMPN------------GDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 234
Query 178 KW--------RGHLIA-WANNMGVKIFDIISKQRITNVPRDD 210
+W G LIA +N+ V+++ + +K+ + +
Sbjct 235 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>sp|P43034|LIS1_HUMAN Platelet-activating factor acetylhydrolase
IB subunit beta OS=Homo sapiens OX=9606 GN=PAFAH1B1 PE=1
SV=2
Length=410
Score = 37.4 bits (85), Expect = 0.62, Method: Composition-based stats.
Identities = 25/162 (15%), Positives = 59/162 (36%), Gaps = 25/162 (15%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + + IS D SG+ + CS D ++++ E
Sbjct 127 SEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIR 186
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRSV 177
D + +A+ P+ G ++ R + W+ + +
Sbjct 187 TMHGHDHNVSSVAIMPN------------GDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 234
Query 178 KW--------RGHLIA-WANNMGVKIFDIISKQRITNVPRDD 210
+W G LIA +N+ V+++ + +K+ + +
Sbjct 235 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>sp|O22785|PR19B_ARATH Pre-mRNA-processing factor 19 homolog 2
OS=Arabidopsis thaliana OX=3702 GN=PRP19B PE=1 SV=3
Length=525
Score = 37.4 bits (85), Expect = 0.62, Method: Composition-based stats.
Identities = 22/89 (25%), Positives = 34/89 (38%), Gaps = 4/89 (4%)
Query 49 SCMTVHDKFLALGTHYG--KVYLLDVQGNI-TQKFDVSPVKINQISLDESGEHMGVCSED 105
+ H L LGT V + DV+ KFD ++ IS E+G + +ED
Sbjct 357 TAAAFHPDGLILGTGTSQSVVKIWDVKSQANVAKFDGHTGEVTAISFSENGYFLATAAED 416
Query 106 GKVQVFGLYSGEEFHETFDCPIKIIAVHP 134
G V+++ L F + P
Sbjct 417 G-VRLWDLRKLRNFKSFLSADANSVEFDP 444
>sp|Q54SF9|MHCKD_DICDI Myosin heavy chain kinase D OS=Dictyostelium
discoideum OX=44689 GN=mhkD PE=3 SV=1
Length=941
Score = 37.8 bits (86), Expect = 0.62, Method: Composition-based stats.
Identities = 12/67 (18%), Positives = 28/67 (42%), Gaps = 2/67 (3%)
Query 77 TQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE--TFDCPIKIIAVHP 134
K + ++N + +D + CS D +++++ L + + IK I +
Sbjct 736 IGKLEDHTAEVNDMCIDIENNFLVSCSFDKQIKIYDLSTFKCIKSLNAHGKSIKSIYMSG 795
Query 135 HFVRSSC 141
++ SS
Sbjct 796 KYLFSSS 802
>sp|Q9XWH0|BUB3_CAEEL Mitotic checkpoint protein bub-3 OS=Caenorhabditis
elegans OX=6239 GN=bub-3 PE=1 SV=1
Length=343
Score = 37.0 bits (84), Expect = 0.62, Method: Composition-based stats.
Identities = 43/190 (23%), Positives = 75/190 (39%), Gaps = 32/190 (17%)
Query 47 AASCMTVHDKFLALGTHYGKVYLLDVQGNITQ-KFDVSPVK--INQISLDESGEHMGVCS 103
+ M V + +GT K+++ D + + SP+K + +GE V S
Sbjct 154 SVYAMDVLKHTILVGTKDRKIFMYDSRKLREPLQVRDSPLKYQTRAVQFFPTGEAFVVSS 213
Query 104 EDGKVQVFGLY-SGEEF---HETFDC-------------PIKIIAVHPHFVRSSCKQFVT 146
+G+V V + SGEE F C P+ +A HP + F T
Sbjct 214 IEGRVAVEYVDQSGEEMMKRKYAFKCHREKDTDGTELIHPVHTVAFHPKYGT-----FAT 268
Query 147 GGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR--GHLIAWANNMGVKIFDIISKQRIT 204
GG ++ NR + LH+ E +I S+ + G +A A + + +
Sbjct 269 GGADGIVNIWDPFNRKRIIQLHKFETSISSLSFNEDGSQLAIA-----TSYQYEKEIDPS 323
Query 205 NVPRDDISLR 214
+P + I++R
Sbjct 324 PLPNNSITIR 333
>sp|O14301|YE85_SCHPO Uncharacterized WD repeat-containing protein
C9G1.05 OS=Schizosaccharomyces pombe (strain 972 / ATCC
24843) OX=284812 GN=SPAC9G1.05 PE=3 SV=1
Length=595
Score = 37.4 bits (85), Expect = 0.63, Method: Composition-based stats.
Identities = 21/89 (24%), Positives = 37/89 (42%), Gaps = 14/89 (16%)
Query 48 ASCMTVH--DKFLALGTHYGKVYLLDVQG--NITQKFDVSPVKINQISLDESGEHMGVCS 103
+C+ K+LA G GKV L D IT ++ +I +S + H+ S
Sbjct 482 ITCLAYSPDGKYLACGDASGKVVLYDANSREVITSRWAFHTGRILGMSWNAKSTHLATAS 541
Query 104 EDGKVQVFGLYSGEEFHETFDCPIKIIAV 132
D + ++ + + P+K IA+
Sbjct 542 LDTNIHIYSV----------ERPMKYIAM 560
>sp|P63004|LIS1_RAT Platelet-activating factor acetylhydrolase
IB subunit alpha OS=Rattus norvegicus OX=10116 GN=Pafah1b1
PE=1 SV=2
Length=410
Score = 37.4 bits (85), Expect = 0.63, Method: Composition-based stats.
Identities = 25/162 (15%), Positives = 59/162 (36%), Gaps = 25/162 (15%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + + IS D SG+ + CS D ++++ E
Sbjct 127 SEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIR 186
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRSV 177
D + +A+ P+ G ++ R + W+ + +
Sbjct 187 TMHGHDHNVSSVAIMPN------------GDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 234
Query 178 KW--------RGHLIA-WANNMGVKIFDIISKQRITNVPRDD 210
+W G LIA +N+ V+++ + +K+ + +
Sbjct 235 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>sp|P63005|LIS1_MOUSE Platelet-activating factor acetylhydrolase
IB subunit beta OS=Mus musculus OX=10090 GN=Pafah1b1 PE=1
SV=2
Length=410
Score = 37.4 bits (85), Expect = 0.63, Method: Composition-based stats.
Identities = 25/162 (15%), Positives = 59/162 (36%), Gaps = 25/162 (15%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + + IS D SG+ + CS D ++++ E
Sbjct 127 SEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIR 186
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRSV 177
D + +A+ P+ G ++ R + W+ + +
Sbjct 187 TMHGHDHNVSSVAIMPN------------GDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 234
Query 178 KW--------RGHLIA-WANNMGVKIFDIISKQRITNVPRDD 210
+W G LIA +N+ V+++ + +K+ + +
Sbjct 235 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>sp|B0LSW3|LIS1_FELCA Platelet-activating factor acetylhydrolase
IB subunit beta OS=Felis catus OX=9685 GN=PAFAH1B1 PE=2 SV=1
Length=410
Score = 37.4 bits (85), Expect = 0.63, Method: Composition-based stats.
Identities = 25/162 (15%), Positives = 59/162 (36%), Gaps = 25/162 (15%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + + IS D SG+ + CS D ++++ E
Sbjct 127 SEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIR 186
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRSV 177
D + +A+ P+ G ++ R + W+ + +
Sbjct 187 TMHGHDHNVSSVAIMPN------------GDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 234
Query 178 KW--------RGHLIA-WANNMGVKIFDIISKQRITNVPRDD 210
+W G LIA +N+ V+++ + +K+ + +
Sbjct 235 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>sp|Q9BQ87|TBL1Y_HUMAN F-box-like/WD repeat-containing protein
TBL1Y OS=Homo sapiens OX=9606 GN=TBL1Y PE=1 SV=1
Length=522
Score = 37.4 bits (85), Expect = 0.63, Method: Composition-based stats.
Identities = 16/83 (19%), Positives = 30/83 (36%), Gaps = 1/83 (1%)
Query 36 SNGVTEILQKDAASCMTVHD-KFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDE 94
G KD S D LA+G++ G + GN+ I + ++
Sbjct 227 EGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIWTENGNLASTLGQHKGPIFALKWNK 286
Query 95 SGEHMGVCSEDGKVQVFGLYSGE 117
G ++ D ++ ++GE
Sbjct 287 KGNYVLSAGVDKTTIIWDAHTGE 309
>sp|O35142|COPB2_RAT Coatomer subunit beta' OS=Rattus norvegicus
OX=10116 GN=Copb2 PE=1 SV=3
Length=905
Score = 37.4 bits (85), Expect = 0.63, Method: Composition-based stats.
Identities = 35/224 (16%), Positives = 77/224 (34%), Gaps = 20/224 (9%)
Query 34 RLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
RL D + +H + ++ + G V + + + + F+V + +
Sbjct 4 RLDIKRKLTAMSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAA 63
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFH--ETFDCPIKIIAVHPHFVRSSCKQFVTGG 148
+ ++D +++VF + E H E I+ IAVHP + +T
Sbjct 64 KFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHP-----TQPFILTSS 118
Query 149 KKLLLFERSWMNRWKSAVLHEGEGN-----IRSVKWRGHLIAWANNMGVKIFDIISKQRI 203
+L+ W +W + + EG + + + K + + + +K++ + S
Sbjct 119 DDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPN 178
Query 204 TNVPRDD-----ISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCS 242
+ + I L + L+ W K C
Sbjct 179 FTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCV 222
>sp|Q94A40|COPA1_ARATH Coatomer subunit alpha-1 OS=Arabidopsis
thaliana OX=3702 GN=At1g62020 PE=2 SV=2
Length=1216
Score = 37.8 bits (86), Expect = 0.64, Method: Composition-based stats.
Identities = 29/158 (18%), Positives = 60/158 (38%), Gaps = 17/158 (11%)
Query 63 HYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEF-- 119
H G + L D + G + +FD + + S +D K++V+ +
Sbjct 29 HSGVIQLWDYRMGTLIDRFDEHEGPVRGVHFHNSQPLFVSGGDDYKIKVWNYKNHRCLFT 88
Query 120 ---HETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRS 176
H + I+ + H + V+ + +W +R +VL +
Sbjct 89 LLGHLDY---IRTVQFHHEYPW-----IVSASDDQTIRIWNWQSRTCVSVLTGHNHYVMC 140
Query 177 VKWR--GHLIAWAN-NMGVKIFDIISKQRITNVPRDDI 211
+ L+ A+ + V+++DI + ++ T P DDI
Sbjct 141 ASFHPKEDLVVSASLDQTVRVWDIGALRKKTVSPADDI 178
>sp|Q9GL51|LIS1_PIG Platelet-activating factor acetylhydrolase
IB subunit alpha OS=Sus scrofa OX=9823 GN=PAFAH1B1 PE=2 SV=3
Length=410
Score = 37.0 bits (84), Expect = 0.66, Method: Composition-based stats.
Identities = 14/77 (18%), Positives = 31/77 (40%), Gaps = 3/77 (4%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + + IS D SG+ + CS D ++++ E
Sbjct 127 SEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIR 186
Query 119 FHETFDCPIKIIAVHPH 135
D + +A+ P+
Sbjct 187 TMHGHDHNVSSVAIMPN 203
>sp|P43033|LIS1_BOVIN Platelet-activating factor acetylhydrolase
IB subunit beta OS=Bos taurus OX=9913 GN=PAFAH1B1 PE=1 SV=2
Length=410
Score = 37.0 bits (84), Expect = 0.66, Method: Composition-based stats.
Identities = 25/162 (15%), Positives = 59/162 (36%), Gaps = 25/162 (15%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + + IS D SG+ + CS D ++++ E
Sbjct 127 SEDATIKVWDYETGDFERTLKGHTDSVEDISFDHSGKLLASCSADMTIKLWDFQGFECIR 186
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRSV 177
D + +A+ P+ G ++ R + W+ + +
Sbjct 187 TMHGHDHNVSSVAIMPN------------GDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 234
Query 178 KW--------RGHLIA-WANNMGVKIFDIISKQRITNVPRDD 210
+W G LIA +N+ V+++ + +K+ + +
Sbjct 235 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>sp|O88879|APAF_MOUSE Apoptotic protease-activating factor 1 OS=Mus
musculus OX=10090 GN=Apaf1 PE=1 SV=3
Length=1249
Score = 37.4 bits (85), Expect = 0.67, Method: Composition-based stats.
Identities = 15/73 (21%), Positives = 32/73 (44%), Gaps = 3/73 (4%)
Query 48 ASCMTV--HDKFLALGTHYGKVYLLDVQGN-ITQKFDVSPVKINQISLDESGEHMGVCSE 104
SC + H +++A G G + ++++ N + + I G+ + SE
Sbjct 964 VSCCCLSPHLEYVAFGDEDGAIKIIELPNNRVFSSGVGHKKAVRHIQFTADGKTLISSSE 1023
Query 105 DGKVQVFGLYSGE 117
D +QV+ +G+
Sbjct 1024 DSVIQVWNWQTGD 1036
>sp|Q2UG43|SEC13_ASPOR Protein transport protein sec13 OS=Aspergillus
oryzae (strain ATCC 42149 / RIB 40) OX=510516 GN=sec13
PE=3 SV=1
Length=294
Score = 37.0 bits (84), Expect = 0.67, Method: Composition-based stats.
Identities = 45/188 (24%), Positives = 68/188 (36%), Gaps = 37/188 (20%)
Query 33 ERLSNGVTEILQKDAASCMT-VHDKF---LALGTHYGKVYLL-DVQGNITQ--------- 78
RL + + A C+ H KF LA ++ GKV + + N T
Sbjct 32 HRLVETLKG--HEGAVWCIAWAHPKFGTILASSSYDGKVLIWREQHQNTTSPVAVNTWTK 89
Query 79 --KFDVSPVKINQISL--DESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCP---IKIIA 131
F + +N +S ESG + S DG V V H+ F + I+
Sbjct 90 VFDFSLHTASVNMVSWAPHESGCLLACASSDGHVSVLEFQDNSWTHQIFHAHGMGVNSIS 149
Query 132 VHPHFVRSS----------CKQFVTGGKKLLLFERSWMNRWKSAVL-HEGEGN---IRSV 177
P S ++FVTGG LL + + KS L EG+ +R V
Sbjct 150 WAPAASPGSLISANPGPGQQRRFVTGGSDNLLKIWDYNSETKSYNLSQTLEGHSDWVRDV 209
Query 178 KWRGHLIA 185
W +++
Sbjct 210 AWSPSILS 217
>sp|Q5RKI0|WDR1_RAT WD repeat-containing protein 1 OS=Rattus norvegicus
OX=10116 GN=Wdr1 PE=1 SV=3
Length=606
Score = 37.4 bits (85), Expect = 0.69, Method: Composition-based stats.
Identities = 20/103 (19%), Positives = 37/103 (36%), Gaps = 11/103 (11%)
Query 58 LALGTHYGKVYLLDVQGNIT---QKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL- 113
+A+G G V + + G K + + ++ G + VC V VF +
Sbjct 460 VAVGGSDGNVRVYSILGATLKDEGKLLEAKGPVTDLAYSHDGAFLAVCDASKVVTVFSVA 519
Query 114 --YSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLF 154
YS I +A P + F +GG ++++
Sbjct 520 DGYSENNVFYGHHAKIVCLAWSPD-----NEHFASGGMDMMVY 557
>sp|C5DJV1|RTC1_LACTC Restriction of telomere capping protein
1 OS=Lachancea thermotolerans (strain ATCC 56472 / CBS 6340
/ NRRL Y-8284) OX=559295 GN=RTC1 PE=3 SV=1
Length=1290
Score = 37.4 bits (85), Expect = 0.69, Method: Composition-based stats.
Identities = 34/143 (24%), Positives = 52/143 (36%), Gaps = 26/143 (18%)
Query 711 TGLLNNIGTHVDPILLIHRIKEGMEIPNLRD--SLVKILQDYNLQILLR---EGCKKILV 765
T ++ N + I ++H+ + NL IL+ N Q +R E CKK+LV
Sbjct 1147 TTVVKNALSEF--INILHKYELFEIAANLLKFCPWDDILEAGNGQCTVRIYCERCKKLLV 1204
Query 766 ADSLS--LLKKMHRTQMKGV-----------LVDEENICESCLSPILPSDAAKPFSVVVF 812
+S ++ RT + V +C C P+ K + V
Sbjct 1205 NESSKEKFTEEWKRTGRQEVMKRFGYWYCDNCSKRNTLCVLCEQPL------KKLTFCVL 1258
Query 813 HCRHMFHKECLPMPSMNSAAQFC 835
+C H H EC MN C
Sbjct 1259 NCGHEGHPECFKKWFMNEEMSEC 1281
>sp|Q08109|HRD1_YEAST ERAD-associated E3 ubiquitin-protein ligase
HRD1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=HRD1 PE=1 SV=1
Length=551
Score = 37.4 bits (85), Expect = 0.70, Method: Composition-based stats.
Identities = 23/105 (22%), Positives = 39/105 (37%), Gaps = 10/105 (10%)
Query 739 LRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPI 798
L+D + IL Y L + + D + + + Q +++NIC C+ +
Sbjct 300 LKDVVWDILALYQSGTSLWKIWRNNKQLDDTLVTVTVEQLQNSA---NDDNICIICMDEL 356
Query 799 LPSDAAKPFS-----VVVFHCRHMFHKECLPMPSMNSAAQFCNIC 838
+ S + + C H+ H CL S Q C IC
Sbjct 357 IHSPNQQTWKNKNKKPKRLPCGHILHLSCLKNWMERS--QTCPIC 399
>sp|C4YN69|RTC1_CANAW Restriction of telomere capping protein
1 OS=Candida albicans (strain WO-1) OX=294748 GN=RTC1 PE=3 SV=1
Length=1088
Score = 37.4 bits (85), Expect = 0.70, Method: Composition-based stats.
Identities = 25/129 (19%), Positives = 43/129 (33%), Gaps = 31/129 (24%)
Query 58 LALGTHYGKVYLLDV----QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
+A G G V + + Q +T K+ IN + ES + S+DG ++++ L
Sbjct 148 IATGLSNGVVSIYKISPNGQSKVTGKYSDHNRTINSLDFIESENQLLSGSQDGTIKLWDL 207
Query 114 YSGE---------EFHETFDCPIKIIAVHPHFVRSSCKQFVT---------------GGK 149
S H PI+ PH + ++ G
Sbjct 208 RSSSTKPVMTVQANLHSD---PIRACQYSPHSAVRNKICVLSVHDSGALCKFDLRTKSGG 264
Query 150 KLLLFERSW 158
K+ E+ W
Sbjct 265 KVYSPEKKW 273
>sp|Q5ACL4|RTC1_CANAL Restriction of telomere capping protein
1 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561
GN=RTC1 PE=3 SV=1
Length=1088
Score = 37.4 bits (85), Expect = 0.70, Method: Composition-based stats.
Identities = 25/129 (19%), Positives = 43/129 (33%), Gaps = 31/129 (24%)
Query 58 LALGTHYGKVYLLDV----QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
+A G G V + + Q +T K+ IN + ES + S+DG ++++ L
Sbjct 148 IATGLSNGVVSIYKISPNGQSKVTGKYSDHNRTINSLDFIESENQLLSGSQDGTIKLWDL 207
Query 114 YSGE---------EFHETFDCPIKIIAVHPHFVRSSCKQFVT---------------GGK 149
S H PI+ PH + ++ G
Sbjct 208 RSSSTKPVMTVQANLHSD---PIRACQYSPHSAVRNKICVLSVHDSGALCKFDLRTKSGG 264
Query 150 KLLLFERSW 158
K+ E+ W
Sbjct 265 KVYSPEKKW 273
>sp|Q8K4P0|WDR33_MOUSE pre-mRNA 3' end processing protein WDR33
OS=Mus musculus OX=10090 GN=Wdr33 PE=1 SV=1
Length=1330
Score = 37.4 bits (85), Expect = 0.71, Method: Composition-based stats.
Identities = 16/74 (22%), Positives = 25/74 (34%), Gaps = 2/74 (3%)
Query 63 HYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYS--GEEFH 120
H G V N + F I + S + CS+DG V+++ E
Sbjct 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL 240
Query 121 ETFDCPIKIIAVHP 134
+K + HP
Sbjct 241 RGHGADVKCVDWHP 254
>sp|Q9C0J8|WDR33_HUMAN pre-mRNA 3' end processing protein WDR33
OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2
Length=1336
Score = 37.4 bits (85), Expect = 0.71, Method: Composition-based stats.
Identities = 16/74 (22%), Positives = 25/74 (34%), Gaps = 2/74 (3%)
Query 63 HYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYS--GEEFH 120
H G V N + F I + S + CS+DG V+++ E
Sbjct 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL 240
Query 121 ETFDCPIKIIAVHP 134
+K + HP
Sbjct 241 RGHGADVKCVDWHP 254
>sp|O76734|TUP1_DICDI General transcriptional corepressor tupA
OS=Dictyostelium discoideum OX=44689 GN=tupA PE=2 SV=1
Length=579
Score = 37.4 bits (85), Expect = 0.72, Method: Composition-based stats.
Identities = 28/164 (17%), Positives = 62/164 (38%), Gaps = 18/164 (11%)
Query 1 MAEAEEQETG--SLEESTDESEEEESE----EEPKLKYERLSNGVTEILQKDAASCMTVH 54
M E +E++ E S + +E+ ++ P ++ + + + C+
Sbjct 231 MEEVKEEDRRRHDTEMSEENGKEKGTDWLVGYNPSVQTNLNIDLLHNLQHNSVVCCVNFS 290
Query 55 D--KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVK-----INQISLDESGEHMGVCSEDG 106
+ K+LA G + + DV G F K I + G ++ +ED
Sbjct 291 NDGKYLATGCNRSA-QIYDVDTGKKVHAFVDESEKDGDLYIRSVCFSPDGNYLATGAEDK 349
Query 107 KVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKK 150
V+V+ +++ + H + + I ++ S + V+G
Sbjct 350 TVKVWDIHTKKIQHTFYGHELDIYSLD---YSSDGRFIVSGSGD 390
>sp|D4D8P3|SCONB_TRIVH Probable E3 ubiquitin ligase complex SCF
subunit sconB OS=Trichophyton verrucosum (strain HKI 0517)
OX=663202 GN=sconB PE=3 SV=1
Length=663
Score = 37.4 bits (85), Expect = 0.73, Method: Composition-based stats.
Identities = 14/72 (19%), Positives = 30/72 (42%), Gaps = 0/72 (0%)
Query 50 CMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQ 109
C+ LA G+ + + + T+ +N + LD + + S+D V+
Sbjct 407 CLHFDSTTLASGSKDNTIKIWNFHDKSTRILRGHADWVNSVKLDTASRTVFSASDDLTVR 466
Query 110 VFGLYSGEEFHE 121
++ L +G+ H
Sbjct 467 IWDLDTGKCIHS 478
>sp|D4AM37|SCONB_ARTBC Probable E3 ubiquitin ligase complex SCF
subunit sconB OS=Arthroderma benhamiae (strain ATCC MYA-4681
/ CBS 112371) OX=663331 GN=sconB PE=3 SV=1
Length=663
Score = 37.4 bits (85), Expect = 0.73, Method: Composition-based stats.
Identities = 14/72 (19%), Positives = 30/72 (42%), Gaps = 0/72 (0%)
Query 50 CMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQ 109
C+ LA G+ + + + T+ +N + LD + + S+D V+
Sbjct 407 CLHFDSTTLASGSKDNTIKIWNFHDKSTRILRGHADWVNSVKLDTASRTVFSASDDLTVR 466
Query 110 VFGLYSGEEFHE 121
++ L +G+ H
Sbjct 467 IWDLDTGKCIHS 478
>sp|Q5ZME8|SMU1_CHICK WD40 repeat-containing protein SMU1 OS=Gallus
gallus OX=9031 GN=SMU1 PE=2 SV=1
Length=513
Score = 37.0 bits (84), Expect = 0.74, Method: Composition-based stats.
Identities = 10/46 (22%), Positives = 22/46 (48%), Gaps = 0/46 (0%)
Query 72 VQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
G ++F +N+ + + G ++ S DG V+V+ + + E
Sbjct 337 KSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKVWNVKTTE 382
>sp|O88491|NSD1_MOUSE Histone-lysine N-methyltransferase, H3 lysine-36
specific OS=Mus musculus OX=10090 GN=Nsd1 PE=1 SV=1
Length=2588
Score = 37.4 bits (85), Expect = 0.79, Method: Composition-based stats.
Identities = 21/91 (23%), Positives = 35/91 (38%), Gaps = 11/91 (12%)
Query 750 YNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSP--ILPSDAAKPF 807
+ +E ++ + D K + + G +EN+C++C +L +A
Sbjct 1403 HRTAASPKEILEEGVEHDPGMSASKKLQVERGGGAALKENVCQNCEKLGELLLCEA---- 1458
Query 808 SVVVFHCRHMFHKECLPMPSMNSAAQFCNIC 838
C FH ECL +P M CN C
Sbjct 1459 -----QCCGAFHLECLGLPEMPRGKFICNEC 1484
>sp|Q7ZVF0|POC1A_DANRE POC1 centriolar protein homolog A OS=Danio
rerio OX=7955 GN=poc1a PE=2 SV=1
Length=416
Score = 37.0 bits (84), Expect = 0.80, Method: Composition-based stats.
Identities = 21/94 (22%), Positives = 36/94 (38%), Gaps = 4/94 (4%)
Query 58 LALGTHYGKVYLLDVQGNIT-QKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSG 116
+A + V + D++ + Q + V +N +S SG H+ S D +++ L G
Sbjct 201 IATASSDNTVRVWDIRTHTLLQHYQVHSAAVNALSFHPSGNHLLTASSDSTLKILDLLEG 260
Query 117 EEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKK 150
+ V F R S QF + G
Sbjct 261 RLLYTLHGHQGSASCVS--FSR-SGDQFASAGSD 291
>sp|A1CUD6|LIS11_ASPCL Nuclear distribution protein nudF 1 OS=Aspergillus
clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816
/ NCTC 3887 / NRRL 1 / QM 1276 / 107) OX=344612 GN=nudF-1
PE=3 SV=1
Length=467
Score = 37.0 bits (84), Expect = 0.80, Method: Composition-based stats.
Identities = 10/55 (18%), Positives = 24/55 (44%), Gaps = 0/55 (0%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKV 108
+F A G+ + L D +GN+ + + ++ G+++ S+D +
Sbjct 326 SAEFFATGSRDKTIRLWDSRGNLIKTLVGHDNWVRALAFHPGGKYLLSVSDDKTI 380
>sp|P87314|HIR1_SCHPO Protein hir1 OS=Schizosaccharomyces pombe
(strain 972 / ATCC 24843) OX=284812 GN=hip1 PE=1 SV=1
Length=932
Score = 37.4 bits (85), Expect = 0.80, Method: Composition-based stats.
Identities = 30/216 (14%), Positives = 65/216 (30%), Gaps = 40/216 (19%)
Query 77 TQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHF 136
++ + + I+ D +G++ S+D ++V+ + S +T P + +F
Sbjct 169 LKRIEAHQSHVKGITFDPAGKYFATESDDRTIKVWRV-SDFSIEKTITGPFNNSPLSTYF 227
Query 137 VRSSCKQFVTGGKKLLLFERSWMNRWKSAVL-HEGEGNIRSVKWRGHLIAWANNMGVKIF 195
R S W K + G + V I
Sbjct 228 RRPS-----------------WSPDGKHIAAPNAMNGPVSCVS---------------II 255
Query 196 DIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERH-ASEMRDL 254
+ + N+ + + + L N L+ + C ++R + L
Sbjct 256 ERGTWTSEINLIGHEGPVEVTAFNPKLFRDKNDKLV-----CILACGGQDRSLSIWSSAL 310
Query 255 PSRYVEIVSQFETEFYISGLAPLCDQLVVLSYVKEI 290
P + + F+ +P L + SY +
Sbjct 311 PRPLLSCQNVFQKSIGDVCWSPDGLSLFLCSYDGNV 346
>sp|Q4V7Z1|POC1B_XENLA POC1 centriolar protein homolog B OS=Xenopus
laevis OX=8355 GN=poc1b PE=1 SV=1
Length=468
Score = 37.0 bits (84), Expect = 0.81, Method: Composition-based stats.
Identities = 19/96 (20%), Positives = 37/96 (39%), Gaps = 8/96 (8%)
Query 58 LALGTHYGKVYLLDVQGN-ITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSG 116
+A V + D++ N + Q + V ++ +S SG ++ S DG +++ L G
Sbjct 201 VASAGADSTVKVWDIRMNKLLQHYQVHNAGVSSLSFHPSGNYLLTASSDGTLKILDLLEG 260
Query 117 EEFH--ETFDCPIKIIAVHPHFVRSSCKQFVTGGKK 150
+ P+ + S QF +G
Sbjct 261 RLIYTLHGHQGPVLSVTFS-----KSGDQFASGATD 291
>sp|Q177G4|HPS5_AEDAE BLOC-2 complex member HPS5 homolog OS=Aedes
aegypti OX=7159 GN=p PE=3 SV=1
Length=845
Score = 37.0 bits (84), Expect = 0.82, Method: Composition-based stats.
Identities = 16/82 (20%), Positives = 37/82 (45%), Gaps = 4/82 (5%)
Query 33 ERLSNGVTEILQKD---AASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPV-KIN 88
L++ + L+ +C V +K++ G + G +Y+ D + S + I+
Sbjct 16 TELTSAIQLPLRNTRRIKFTCFDVSEKYIIFGANSGSLYVYDRESVNFLSIIPSQLGTIS 75
Query 89 QISLDESGEHMGVCSEDGKVQV 110
Q+ + +G+ + V + G + V
Sbjct 76 QVQISSNGKQIAVANMRGAIGV 97
>sp|Q91XF4|RN167_MOUSE E3 ubiquitin-protein ligase RNF167 OS=Mus
musculus OX=10090 GN=Rnf167 PE=2 SV=1
Length=347
Score = 36.6 bits (83), Expect = 0.86, Method: Composition-based stats.
Identities = 18/61 (30%), Positives = 26/61 (43%), Gaps = 7/61 (11%)
Query 786 DEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAK-NRG 844
DE ++C CL D + V C H +H C+ P + + C IC +RG
Sbjct 225 DEYDVCAICLDEYEDGDKLR-----VLPCAHAYHSRCVD-PWLTQTRKTCPICKQPVHRG 278
Query 845 P 845
P
Sbjct 279 P 279
>sp|Q5B563|SEC13_EMENI Protein transport protein sec13 OS=Emericella
nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 /
NRRL 194 / M139) OX=227321 GN=sec13 PE=3 SV=1
Length=309
Score = 36.6 bits (83), Expect = 0.89, Method: Composition-based stats.
Identities = 37/184 (20%), Positives = 63/184 (34%), Gaps = 18/184 (10%)
Query 79 KFDVSPVKINQISL--DESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCP---IKIIAVH 133
F + +N IS E+G + S DG V V H+ F + I+
Sbjct 107 DFSLHTASVNMISWAPHETGCLLACASSDGHVSVLEFRDNSWTHQIFHAHGMGVNSISWA 166
Query 134 PHFVRSS----------CKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHL 183
P S ++FVTGG LL + W ++ + + W
Sbjct 167 PAASPGSLVSSNPGIGQQRRFVTGGSDNLL--KIWDYNPETKTYNATQTLEGHSDWVRD- 223
Query 184 IAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSV 243
+AW+ ++ K + + Q T + P + + DNV + W S + +V
Sbjct 224 VAWSPSILSKSYIASASQDKTVRVWTADASNPGQWTSQVLEFDNVLWRVSWSPSGNILAV 283
Query 244 KERH 247
Sbjct 284 SGGD 287
>sp|Q54J37|STRN_DICDI Striatin homolog OS=Dictyostelium discoideum
OX=44689 GN=strn PE=3 SV=1
Length=827
Score = 37.0 bits (84), Expect = 0.89, Method: Composition-based stats.
Identities = 19/100 (19%), Positives = 39/100 (39%), Gaps = 12/100 (12%)
Query 61 GTHYGKVYLLDVQGN-ITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSG--- 116
G+ K+ D+ N + I+ +++D SG ++ C+ D ++ + + S
Sbjct 729 GSEDHKIEFFDLNSNTVVHSMIAHSNSISSLTIDPSGLYIASCAHDSSIRFWDISSKTCI 788
Query 117 ---EEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLL 153
+D I I HP+ F +GG ++
Sbjct 789 QDLNSHRPKYDESIHCIKYHPNKGY-----FASGGADSVI 823
>sp|Q6CEI9|HSV2_YARLI SVP1-like protein 2 OS=Yarrowia lipolytica
(strain CLIB 122 / E 150) OX=284591 GN=HSV2 PE=3 SV=1
Length=359
Score = 36.6 bits (83), Expect = 0.90, Method: Composition-based stats.
Identities = 12/77 (16%), Positives = 25/77 (32%), Gaps = 1/77 (1%)
Query 75 NITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPI-KIIAVH 133
N+ + ++L G + CS++G + S F + + + +
Sbjct 179 NLVSIIRAHKSPVRCVTLSADGSVVASCSDNGTLVRLHSTSNTALLHEFRRGLDRAVVYN 238
Query 134 PHFVRSSCKQFVTGGKK 150
F S + V K
Sbjct 239 MAFSPSGSRLAVLSDKN 255
>sp|O74845|HIF2_SCHPO Set3 complex subunit hif2 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=hif2 PE=1
SV=1
Length=564
Score = 36.6 bits (83), Expect = 0.99, Method: Composition-based stats.
Identities = 15/93 (16%), Positives = 35/93 (38%), Gaps = 7/93 (8%)
Query 21 EEESEEEPKLKYERLSNGVTEILQKDAASCMTVHDK--FLALGTHYGKVYLLDVQGNITQ 78
EE+++ + K Y + + + ++ FLA G + + D G+
Sbjct 245 EEQNDFKAKTDY-----CLQSSFDNQDITGVAWNNSGSFLAYAFFSGVIEIYDSHGSQIL 299
Query 79 KFDVSPVKINQISLDESGEHMGVCSEDGKVQVF 111
F + + + + ++ S DG + +F
Sbjct 300 SFHNNKGPVLSLKWSGTDTYLAAGSADGTITLF 332
Score = 36.6 bits (83), Expect = 1.3, Method: Composition-based stats.
Identities = 28/162 (17%), Positives = 55/162 (34%), Gaps = 11/162 (7%)
Query 55 DKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQ---ISLDESGEHMGVCSEDGKVQVF 111
D +LA G+ G + L D D + IS DE +G ++V+
Sbjct 317 DTYLAAGSADGTITLFDQLKQTQYSIDTLASSVLDIEWISFDE----FVTSDVEGSLRVY 372
Query 112 GLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGE 171
+ I + +R S + + L+ R ++ +
Sbjct 373 KVDGKAPVSTVSHAHDNSIVALRYNLRISLLLTASSDTTVKLWSRGDAGAFECLHVFSFS 432
Query 172 GNIRSVKWR----GHLIAWANNMGVKIFDIISKQRITNVPRD 209
+ + W ++A A+N V +++ IS Q++ R
Sbjct 433 SPVNCIDWNLREGTPILAVASNSIVSMYNAISLQQLAVFMRH 474
>sp|Q8HXX0|LIS1_MACFA Platelet-activating factor acetylhydrolase
IB subunit alpha OS=Macaca fascicularis OX=9541 GN=PAFAH1B1
PE=2 SV=3
Length=410
Score = 36.6 bits (83), Expect = 0.99, Method: Composition-based stats.
Identities = 26/162 (16%), Positives = 59/162 (36%), Gaps = 25/162 (15%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + + IS D SG+ + CS D ++++ E
Sbjct 127 SEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLTSCSADMTIKLWDFQGFECIR 186
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRSV 177
D + +A+ P+ G L+ R + W+ + +
Sbjct 187 TMHGHDHNVSSVAIMPN------------GDHLVSASRDKTIKMWEVQTGYCVKTFTGHR 234
Query 178 KW--------RGHLIA-WANNMGVKIFDIISKQRITNVPRDD 210
+W G LIA +N+ V+++ + +K+ + +
Sbjct 235 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>sp|Q9LTA6|WAV3_ARATH E3 ubiquitin-protein ligase WAV3 OS=Arabidopsis
thaliana OX=3702 GN=WAV3 PE=1 SV=1
Length=740
Score = 37.0 bits (84), Expect = 0.99, Method: Composition-based stats.
Identities = 10/52 (19%), Positives = 19/52 (37%), Gaps = 3/52 (6%)
Query 789 NICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSA 840
+ C CL+ + ++ C H FH C+ C +C++
Sbjct 120 STCGICLNSVKTGQGTAKYTA---ECSHAFHFPCIADYVRKQGKLVCPVCNS 168
>sp|Q6ZPG2|WDR90_MOUSE WD repeat-containing protein 90 OS=Mus
musculus OX=10090 GN=Wdr90 PE=1 SV=2
Length=1874
Score = 37.0 bits (84), Expect = 1.00, Method: Composition-based stats.
Identities = 18/72 (25%), Positives = 30/72 (42%), Gaps = 1/72 (1%)
Query 47 AASCMTVHDKFLALGTHYGKV-YLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSED 105
++ +GT G + Y+ +G T+ K+N++ H C ED
Sbjct 1523 VSASFDSGMDMGVVGTTAGTIWYISWTEGTSTRLISGHRTKVNEVVFSPGESHCATCGED 1582
Query 106 GKVQVFGLYSGE 117
G V+V+ L S E
Sbjct 1583 GSVRVWSLASME 1594
>sp|C5JD40|LIS1_BLAGS Nuclear distribution protein PAC1 OS=Blastomyces
gilchristii (strain SLH14081) OX=559298 GN=PAC1 PE=3
SV=1
Length=473
Score = 36.6 bits (83), Expect = 1.0, Method: Composition-based stats.
Identities = 17/110 (15%), Positives = 41/110 (37%), Gaps = 11/110 (10%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
+++A G+ + + D +G + + + + G+++ S+D ++ + L
Sbjct 326 SAEYVATGSRDKTIRVWDSRGTLIKTLIGHDNWVRALVFHPGGKYLLSVSDDKTIRCWDL 385
Query 114 YSGEEFHE-----TFDCPIKIIAVHPHFVRSSCKQFV----TGGKKLLLF 154
+EF + I P+ ++ + V GG L L
Sbjct 386 --SQEFKCVRVVTDAHAFVTCIRWAPNIIKDAGGMGVNGDINGGGSLALS 433
>sp|C5GVJ9|LIS1_AJEDR Nuclear distribution protein PAC1 OS=Ajellomyces
dermatitidis (strain ER-3 / ATCC MYA-2586) OX=559297
GN=PAC1 PE=3 SV=1
Length=473
Score = 36.6 bits (83), Expect = 1.0, Method: Composition-based stats.
Identities = 17/110 (15%), Positives = 41/110 (37%), Gaps = 11/110 (10%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
+++A G+ + + D +G + + + + G+++ S+D ++ + L
Sbjct 326 SAEYVATGSRDKTIRVWDSRGTLIKTLIGHDNWVRALVFHPGGKYLLSVSDDKTIRCWDL 385
Query 114 YSGEEFHE-----TFDCPIKIIAVHPHFVRSSCKQFV----TGGKKLLLF 154
+EF + I P+ ++ + V GG L L
Sbjct 386 --SQEFKCVRVVTDAHAFVTCIRWAPNIIKDAGGMGVNGDINGGGSLALS 433
>sp|Q9LV27|LST81_ARATH Target of rapamycin complex subunit LST8-1
OS=Arabidopsis thaliana OX=3702 GN=LST8-1 PE=1 SV=1
Length=305
Score = 36.2 bits (82), Expect = 1.0, Method: Composition-based stats.
Identities = 31/146 (21%), Positives = 56/146 (38%), Gaps = 14/146 (10%)
Query 55 DKFLALGTHYGKVYLLDVQGNITQ---KFDVSPVKINQISLDESGEHMGVCSEDGKVQVF 111
DK + L DV N Q +D + + + M SEDG V+++
Sbjct 46 DKHYLAAACNPHIRLFDVNSNSPQPVMTYDSHTNNVMAVGFQCDAKWMYSGSEDGTVKIW 105
Query 112 GLYSG--EEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLH- 168
L + ++ +E+ + + +HP+ ++G + + S L
Sbjct 106 DLRAPGCQKEYESVA-AVNTVVLHPNQTE-----LISGDQNGNIRVWDLRANSCSCELVP 159
Query 169 EGEGNIRS--VKWRGHLIAWANNMGV 192
E + +RS V W G ++ ANN G
Sbjct 160 EVDTAVRSLTVMWDGTMVVAANNRGT 185
>sp|P53196|RPN14_YEAST 26S proteasome regulatory subunit RPN14
OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=RPN14 PE=1 SV=1
Length=417
Score = 36.6 bits (83), Expect = 1.0, Method: Composition-based stats.
Identities = 16/74 (22%), Positives = 34/74 (46%), Gaps = 1/74 (1%)
Query 46 DAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFD-VSPVKINQISLDESGEHMGVCSE 104
A + + LGT G + +LD N+ ++ D +I ++ SGE + S+
Sbjct 97 TAVDTAKLQMRRFILGTTEGDIKVLDSNFNLQREIDQAHVSEITKLKFFPSGEALISSSQ 156
Query 105 DGKVQVFGLYSGEE 118
D +++++ + G
Sbjct 157 DMQLKIWSVKDGSN 170
Score = 34.7 bits (78), Expect = 3.5, Method: Composition-based stats.
Identities = 15/76 (20%), Positives = 29/76 (38%), Gaps = 3/76 (4%)
Query 63 HYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE- 121
H G + G Q ++S K N + G+++ G + V ++S E+ +
Sbjct 223 HDGVNSIALFVGTDRQLHEISTSKKNNLEFGTYGKYVIAGHVSGVITVHNVFSKEQTIQL 282
Query 122 --TFDCPIKIIAVHPH 135
F C + V +
Sbjct 283 PSKFTCSCNSLTVDGN 298
>sp|P0CS42|LIS1_CRYNJ Nuclear distribution protein PAC1 OS=Cryptococcus
neoformans var. neoformans serotype D (strain JEC21
/ ATCC MYA-565) OX=214684 GN=PAC1 PE=3 SV=1
Length=433
Score = 36.6 bits (83), Expect = 1.1, Method: Composition-based stats.
Identities = 16/94 (17%), Positives = 32/94 (34%), Gaps = 6/94 (6%)
Query 48 ASCMTVHDK--FLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSE 104
+ + H LA + V L D + G++ + + + D G M CS
Sbjct 108 VTRLAFHPTWTLLASASEDATVKLWDWEAGDMERTLKGHTKAVMDVDFDPRGGLMATCSS 167
Query 105 DGKVQV---FGLYSGEEFHETFDCPIKIIAVHPH 135
D +++ Y+ + D + + P
Sbjct 168 DLTLKLWDTANQYTNVKTLHGHDHSVSSVRFMPD 201
>sp|P0CS43|LIS1_CRYNB Nuclear distribution protein PAC1 OS=Cryptococcus
neoformans var. neoformans serotype D (strain B-3501A)
OX=283643 GN=PAC1 PE=3 SV=1
Length=433
Score = 36.6 bits (83), Expect = 1.1, Method: Composition-based stats.
Identities = 16/94 (17%), Positives = 32/94 (34%), Gaps = 6/94 (6%)
Query 48 ASCMTVHDK--FLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSE 104
+ + H LA + V L D + G++ + + + D G M CS
Sbjct 108 VTRLAFHPTWTLLASASEDATVKLWDWEAGDMERTLKGHTKAVMDVDFDPRGGLMATCSS 167
Query 105 DGKVQV---FGLYSGEEFHETFDCPIKIIAVHPH 135
D +++ Y+ + D + + P
Sbjct 168 DLTLKLWDTANQYTNVKTLHGHDHSVSSVRFMPD 201
>sp|Q23256|WDR53_CAEEL WD repeat-containing protein wdr-5.3 OS=Caenorhabditis
elegans OX=6239 GN=wdr-5.3 PE=3 SV=1
Length=501
Score = 36.6 bits (83), Expect = 1.1, Method: Composition-based stats.
Identities = 30/173 (17%), Positives = 61/173 (35%), Gaps = 17/173 (10%)
Query 56 KFLALGTHYGKVYLLDVQGNIT-QKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
K+L G+ ++ + + Q + IN S + + + S+D V++F +
Sbjct 226 KYLGTGSADKQIKVWNTVDMTYLQTLASHQLGINDFSWSSNSQFIASASDDTTVKIFDVI 285
Query 115 SGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNR----WKSAVLHEG 170
SG + F S G + + R W + K H
Sbjct 286 SGACLRTMRGHTNYVFCCS--FNPQSSLIASAGFDETV---RVWDFKTGLCVKCIPAHSD 340
Query 171 EGNIRSVKWR--GHLIAWANNMG-VKIFDIISKQRITNVPRDDISLRPDMYPC 220
I S+ + G+ +A ++ G ++++D S + + D P + C
Sbjct 341 --PITSISYNHDGNTMATSSYDGCIRVWDAASGSCLKTLV--DTDHAPVTFVC 389
>sp|Q6R2V0|WNK1_PIG Serine/threonine-protein kinase WNK1 OS=Sus
scrofa OX=9823 GN=WNK1 PE=2 SV=3
Length=2376
Score = 37.0 bits (84), Expect = 1.1, Method: Composition-based stats.
Identities = 26/132 (20%), Positives = 55/132 (42%), Gaps = 14/132 (11%)
Query 286 YVKEISEKTEREYCARPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESL 345
Y K + ++ E +RP+L I+ +S + + L + + + L+ E +
Sbjct 1101 YRKSVRSRSRHEKTSRPKLRILN-VSNKGDRVVECQLETHNRKMVTFK-FDLDGDNPEEI 1158
Query 346 FYIVSPRDVVVAKERDQ-DDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINH 404
I+ D ++A ER+ D + ++EK A E+ +++ D G + +
Sbjct 1159 ATIMVNNDFILAIEREAFVDQVREIIEK--------ADEMLSEDVSVEPEGDQG---LEN 1207
Query 405 LVERGDYDIAAR 416
L + DY +
Sbjct 1208 LQGKDDYGFSGS 1219
>sp|Q5XIL0|RN167_RAT E3 ubiquitin-protein ligase RNF167 OS=Rattus
norvegicus OX=10116 GN=Rnf167 PE=2 SV=1
Length=349
Score = 36.2 bits (82), Expect = 1.1, Method: Composition-based stats.
Identities = 17/61 (28%), Positives = 26/61 (43%), Gaps = 7/61 (11%)
Query 786 DEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAK-NRG 844
DE ++C CL D + + C H +H C+ P + + C IC +RG
Sbjct 225 DEYDVCAICLDEYEDGDKLR-----ILPCAHAYHSRCVD-PWLTQTRKTCPICKQPVHRG 278
Query 845 P 845
P
Sbjct 279 P 279
>sp|B5X3C4|LIS1B_SALSA Lissencephaly-1 homolog B OS=Salmo salar
OX=8030 GN=pafah1b1-2 PE=2 SV=1
Length=410
Score = 36.6 bits (83), Expect = 1.1, Method: Composition-based stats.
Identities = 16/96 (17%), Positives = 38/96 (40%), Gaps = 5/96 (5%)
Query 45 KDAASCMTVHDKFLALGTHY--GKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGV 101
+ + + H F + T + + D + G+ + + IS D++G+ +
Sbjct 108 RSPVTRVIFHPVFSVMVTSSEDATIKVWDYEAGDFERTLKGHTDSVQDISFDQTGKLLAS 167
Query 102 CSEDGKVQVFGLYSGE--EFHETFDCPIKIIAVHPH 135
CS D ++++ E D + +A+ P+
Sbjct 168 CSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPN 203
>sp|Q852U6|RHY1A_ARATH Probable E3 ubiquitin-protein ligase RHY1A
OS=Arabidopsis thaliana OX=3702 GN=RHY1A PE=1 SV=1
Length=250
Score = 35.8 bits (81), Expect = 1.1, Method: Composition-based stats.
Identities = 20/86 (23%), Positives = 26/86 (30%), Gaps = 11/86 (13%)
Query 760 CKKILVADSLSLLKKMHRTQMKGVLVDEENI-CESCLSPILPSDAAKPFSVVVFHCRHMF 818
C K + + +HR V E C CL K ++ C H F
Sbjct 171 CNKKPQGLTQDAINCLHRQTFSSAEVKSEMRDCSICLESF-----TKGDMLISLPCTHSF 225
Query 819 HKECLPMPSMNSAAQFCNICSAKNRG 844
H CL N + C C R
Sbjct 226 HSSCL-----NPWLRACGDCPCCRRA 246
>sp|P41811|COPB2_YEAST Coatomer subunit beta' OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SEC27
PE=1 SV=1
Length=889
Score = 36.6 bits (83), Expect = 1.1, Method: Composition-based stats.
Identities = 26/180 (14%), Positives = 69/180 (38%), Gaps = 18/180 (10%)
Query 55 DKFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
++ +G+ ++ + + G F+ P I I++ + ++ S+D V+++
Sbjct 67 KNWIIVGSDDFRIRVFNYNTGEKVVDFEAHPDYIRSIAVHPTKPYVLSGSDDLTVKLWNW 126
Query 114 YSGEEFHETF---DCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEG 170
+ +TF + + +A +P F +G L + W +
Sbjct 127 ENNWALEQTFEGHEHFVMCVAFNP----KDPSTFASGC--LDRTVKVWSLGQSTPNFTLT 180
Query 171 EGNIRSVKWRGHL--------IAWANNMGVKIFDIISKQRITNVPRDDISLRPDMYPCSL 222
G R V + + I ++++ +KI+D +K + + ++ ++ +L
Sbjct 181 TGQERGVNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCVATLEGHMSNVSFAVFHPTL 240
>sp|A5DHD9|SEC13_PICGU Protein transport protein SEC13 OS=Meyerozyma
guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381
/ JCM 1539 / NBRC 10279 / NRRL Y-324) OX=294746 GN=SEC13 PE=3
SV=2
Length=290
Score = 36.2 bits (82), Expect = 1.2, Method: Composition-based stats.
Identities = 33/187 (18%), Positives = 70/187 (37%), Gaps = 17/187 (9%)
Query 82 VSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHET-----FDCPIKIIAV-HPH 135
I+ LD G+ + CS D +++F + E + T + P+ +A HP
Sbjct 7 AHDELIHDAVLDYYGKRLATCSSDKTIKIFEVEGTENYQLTETLVGHEGPVWQVAWAHPK 66
Query 136 FVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEG-EGNIRSVKWRGH-----LIAWANN 189
F + K+L+++ S W H+ + ++ SV W H L+ +++
Sbjct 67 FGSILASC--SYDGKVLVWKESPDRSWSIISEHKVHQASVNSVSWAPHELGAVLLCTSSD 124
Query 190 MGVKIFDIISKQRITNV--PRDDISLRPDMYPCSLCWKDNVTLIIGWGTSV-KVCSVKER 246
V + D T++ I + + + G ++ KV S+
Sbjct 125 GRVSVVDFNDDGTSTHIIFEAHKIGVNSASWAPVDTKSPVRRFVTGGSDNLAKVWSLDAS 184
Query 247 HASEMRD 253
++ + +
Sbjct 185 KSTYVEE 191
>sp|Q803D2|LIS1B_DANRE Lissencephaly-1 homolog B OS=Danio rerio
OX=7955 GN=pafah1b1b PE=2 SV=3
Length=410
Score = 36.2 bits (82), Expect = 1.2, Method: Composition-based stats.
Identities = 13/77 (17%), Positives = 32/77 (42%), Gaps = 3/77 (4%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + + IS D++G+ + CS D ++++ E
Sbjct 127 SEDATIKVWDYEAGDFERTLKGHTDSVQDISFDQTGKLLASCSADMTIKLWDFQGFECIR 186
Query 119 FHETFDCPIKIIAVHPH 135
D + +A+ P+
Sbjct 187 TMHGHDHNVSSVAIMPN 203
>sp|Q8NEG5|ZSWM2_HUMAN E3 ubiquitin-protein ligase ZSWIM2 OS=Homo
sapiens OX=9606 GN=ZSWIM2 PE=1 SV=2
Length=633
Score = 36.6 bits (83), Expect = 1.2, Method: Composition-based stats.
Identities = 20/76 (26%), Positives = 31/76 (41%), Gaps = 8/76 (11%)
Query 781 KGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPM-----PSMNSAAQFC 835
K +D E+IC C +L F F C + H +C+ + + N++ C
Sbjct 137 KQKEIDSEDICSICQELLLEKKLPVTFC--RFGCGNSIHIKCMKILANYQSTSNTSMLKC 194
Query 836 NICSAKNRGPGSAILE 851
+C K P ILE
Sbjct 195 PLCR-KEFAPLKLILE 209
>sp|Q9H4A3|WNK1_HUMAN Serine/threonine-protein kinase WNK1 OS=Homo
sapiens OX=9606 GN=WNK1 PE=1 SV=2
Length=2382
Score = 37.0 bits (84), Expect = 1.2, Method: Composition-based stats.
Identities = 26/132 (20%), Positives = 54/132 (41%), Gaps = 14/132 (11%)
Query 286 YVKEISEKTEREYCARPRLDIIQPLSETCEEISSDALTVRGFQENECRDYHLEYSEGESL 345
Y K + ++ E +RP+L I+ +S + + L + + + L+ E +
Sbjct 1102 YRKSVRSRSRHEKTSRPKLRILN-VSNKGDRVVECQLETHNRKMVTFK-FDLDGDNPEEI 1159
Query 346 FYIVSPRDVVVAKERDQ-DDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGLAYINH 404
I+ D ++A ER+ D + ++EK A E+ +++ D G +
Sbjct 1160 ATIMVNNDFILAIERESFVDQVREIIEK--------ADEMLSEDVSVEPEGDQG---LES 1208
Query 405 LVERGDYDIAAR 416
L + DY +
Sbjct 1209 LQGKDDYGFSGS 1220
>sp|A8JAN3|POC16_CHLRE Centriole proteome protein 16 OS=Chlamydomonas
reinhardtii OX=3055 GN=POC16 PE=1 SV=1
Length=2083
Score = 37.0 bits (84), Expect = 1.2, Method: Composition-based stats.
Identities = 21/82 (26%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query 58 LALGTHYGKVYLLDVQGNITQKF-DVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSG 116
LA+GT G + +L + + +N +++D + + S DG ++++ L +
Sbjct 745 LAVGTENGTLGVLAIPTHAYTTLLRSHCGAVNAVAVDPNRDQYCTVSSDGTLRIWHLATH 804
Query 117 EEFHETFDCP---IKIIAVHPH 135
++ +E FD P + IA HPH
Sbjct 805 QQLYE-FDAPGEAVSAIAYHPH 825
>sp|Q54U63|LVSC_DICDI BEACH domain-containing protein lvsC OS=Dictyostelium
discoideum OX=44689 GN=lvsC PE=4 SV=2
Length=2491
Score = 37.0 bits (84), Expect = 1.2, Method: Composition-based stats.
Identities = 15/92 (16%), Positives = 36/92 (39%), Gaps = 5/92 (5%)
Query 48 ASCMTVHDK--FLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSED 105
S + + ++ + +YL + G + + D +++ I + + E++ E
Sbjct 2359 ISLIAISNQGYIVIYSQADLMIYLYSINGGLLKTVDTHE-RLHSIIISKDSEYLITGGER 2417
Query 106 GKVQVFGLYS--GEEFHETFDCPIKIIAVHPH 135
G V + L++ F PI +A+
Sbjct 2418 GVVVIRTLFNLKPTNHKLVFGTPIHSLAMASD 2449
>sp|A3LQI7|LKA42_PICST Leucine aminopeptidase 2-2 OS=Scheffersomyces
stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 /
NRRL Y-11545) OX=322104 GN=LTA4 PE=3 SV=2
Length=635
Score = 36.6 bits (83), Expect = 1.2, Method: Composition-based stats.
Identities = 17/114 (15%), Positives = 33/114 (29%), Gaps = 20/114 (18%)
Query 375 YEEALMAAEISQKNIKRHKILDIGLAYINHLVERGDYDIA-----ARKCQKILGKNAAL- 428
YE+ + ++ + K+ D +I ++ Y +
Sbjct 399 YEKGFNLLFLIEQTVGGKKVFD---KFIPSYFKKFRYGSLDTYQFVDYLYEFFNDKKVEL 455
Query 429 ----WEYEVYKFKEIGQLKAISPYLPRGDPVLKPLIYEMILHEFLESDYEGFAT 478
WE +YK + P +P+ D L YE+ F +
Sbjct 456 DSIDWESWLYK-------PGMPPVMPKFDTTLADECYELADEWFSAIKNNSYLK 502
>sp|Q0WQX9|WAVH2_ARATH Probable E3 ubiquitin-protein ligase WAVH2
OS=Arabidopsis thaliana OX=3702 GN=WAVH2 PE=1 SV=1
Length=717
Score = 36.6 bits (83), Expect = 1.2, Method: Composition-based stats.
Identities = 15/63 (24%), Positives = 23/63 (37%), Gaps = 5/63 (8%)
Query 786 DEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAK-NRG 844
+ C CL + + + ++ C H FH C+ + C CSA N
Sbjct 135 SNSSRCAICLQRVNSNQSNSTAAIFTAECSHSFHLSCVNG----LEDKRCPFCSAAWNHA 190
Query 845 PGS 847
P S
Sbjct 191 PKS 193
>sp|A8ILK1|CFA52_CHLRE Cilia- and flagella-associated protein
52 OS=Chlamydomonas reinhardtii OX=3055 GN=CFAP52 PE=1 SV=1
Length=615
Score = 36.6 bits (83), Expect = 1.2, Method: Composition-based stats.
Identities = 43/268 (16%), Positives = 103/268 (38%), Gaps = 34/268 (13%)
Query 34 RLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKF---DVSPVKINQI 90
RL + + D + M +++ + G ++ ++ V ++ I
Sbjct 311 RLKEELVQTAHNDKINGMAFPNEYSEVFATCGTGFIRLWHLTTCRELLRIAVPNLECFCI 370
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGE---EFHETFDCPIKIIAVHPHFVRSSCKQFVTG 147
+ G + DGK++ FG SG+ ++ + IA + + ++G
Sbjct 371 AFTTDGSAILSGWSDGKIRAFGPQSGKIIFTINDAHQKAVTAIA-----STADSSRILSG 425
Query 148 GKKLLLFERSWMNRWKSAVLHEG----EGNIRSVKWRGH---LIAWANNMGVKIFDIISK 200
G++ ++ R W S L +G + ++ +G ++ +++ ++D+ +
Sbjct 426 GEEGMV--RVWRIGRTSQTLEASMKDHKGPVNCIRIKGSGDECVSASSDGSCILWDLHTF 483
Query 201 QRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVE 260
+R SL + + S+ + + + ++ GT KV + +R + ++
Sbjct 484 KR-------RTSLFANTFFKSVVYHPDESQLVTAGTDRKVTYWDAYDGNAIRIIDGSDLD 536
Query 261 IVSQFET----EFYISGLAPLCDQLVVL 284
V+ E +SG D+LV L
Sbjct 537 EVNALAVDRDGEALVSG---GGDKLVKL 561
>sp|Q9NB71|HIW_DROME E3 ubiquitin-protein ligase highwire OS=Drosophila
melanogaster OX=7227 GN=hiw PE=1 SV=2
Length=5233
Score = 36.6 bits (83), Expect = 1.2, Method: Composition-based stats.
Identities = 21/102 (21%), Positives = 34/102 (33%), Gaps = 15/102 (15%)
Query 760 CKKILVADSLSLLKKMHRT-QMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMF 818
C L + ++ + + D +++C C L + + C H+F
Sbjct 4959 CLPCLQHVCHTRENELAEELRDPKLTQDADDMCMICFVEALSCAPS-----IHLECGHVF 5013
Query 819 HKECLP--------MPSMNSAAQFCNICSAKNRGP-GSAILE 851
H C P + C IC A + P S ILE
Sbjct 5014 HYHCCKAVLEKRWSGPRITFGFSLCPICKADIQHPLLSDILE 5055
>sp|Q6DIF4|WDR1_XENTR WD repeat-containing protein 1 OS=Xenopus
tropicalis OX=8364 GN=wdr1 PE=2 SV=1
Length=607
Score = 36.6 bits (83), Expect = 1.3, Method: Composition-based stats.
Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 7/79 (9%)
Query 45 KDAASCMTVHDK----FLALGTHYGKVYLLDVQGNITQKF--DVSPVKINQISLDESGEH 98
+ CMTVH+ + G+H G + D + F +++++ LD S +
Sbjct 320 NKSIQCMTVHNSDGRSTIYTGSHDGHINYWDAETGENDTFTGKGHTNQVSRMDLDSSNQ- 378
Query 99 MGVCSEDGKVQVFGLYSGE 117
+ CS D V+ L S +
Sbjct 379 LITCSMDDTVRYTSLTSKD 397
Score = 35.8 bits (81), Expect = 1.8, Method: Composition-based stats.
Identities = 23/103 (22%), Positives = 43/103 (42%), Gaps = 11/103 (11%)
Query 58 LALGTHYGKVYLLDVQGNITQKFDVS-PVK--INQISLDESGEHMGVCSEDGKVQVFGL- 113
+A+G G V+L +QGN + S PVK + ++ G + V + V VF +
Sbjct 460 VAVGGVDGNVHLYSIQGNSLKDEGKSLPVKGAVTDLAYSHDGAFLAVTDANKVVTVFNVA 519
Query 114 --YSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLF 154
YS + + +A P + F + G ++++
Sbjct 520 DGYSEQNVYYGHHAKAVSVAWSPD-----NEHFASSGMDMMVY 557
>sp|P41318|LST8_YEAST Target of rapamycin complex subunit LST8
OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292
GN=LST8 PE=1 SV=1
Length=303
Score = 35.8 bits (81), Expect = 1.3, Method: Composition-based stats.
Identities = 20/85 (24%), Positives = 35/85 (41%), Gaps = 5/85 (6%)
Query 55 DKFLALGTHYGKVYLLDV---QGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVF 111
K LA H V L D+ N F+ + +S + M SEDG ++V+
Sbjct 44 KKLLATAGHQN-VRLYDIRTTNPNPVASFEGHRGNVTSVSFQQDNRWMVTSSEDGTIKVW 102
Query 112 GLYSGE-EFHETFDCPIKIIAVHPH 135
+ S + + P+ + +HP+
Sbjct 103 DVRSPSIPRNYKHNAPVNEVVIHPN 127
>sp|O96028|NSD2_HUMAN Histone-lysine N-methyltransferase NSD2
OS=Homo sapiens OX=9606 GN=NSD2 PE=1 SV=1
Length=1365
Score = 36.6 bits (83), Expect = 1.3, Method: Composition-based stats.
Identities = 14/66 (21%), Positives = 25/66 (38%), Gaps = 11/66 (17%)
Query 777 RTQMKGVLVDEENICESCLSP--ILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQF 834
+ +GV +E +C+ C P +L + C FH CL +
Sbjct 656 KKSERGVTAKKEYVCQLCEKPGSLLLCEGP---------CCGAFHLACLGLSRRPEGRFT 706
Query 835 CNICSA 840
C+ C++
Sbjct 707 CSECAS 712
>sp|Q4RJN5|LIS1_TETNG Lissencephaly-1 homolog OS=Tetraodon nigroviridis
OX=99883 GN=pafah1b1 PE=3 SV=1
Length=410
Score = 36.2 bits (82), Expect = 1.3, Method: Composition-based stats.
Identities = 28/162 (17%), Positives = 61/162 (38%), Gaps = 25/162 (15%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + + IS D +G+ + CS D ++++ S E
Sbjct 127 SEDATIKVWDYETGDFERTLKGHTDSVQDISFDLTGKLLASCSADMTIKLWDFQSFECIR 186
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRSV 177
D + +A+ P+ G ++ R M W+ A + +
Sbjct 187 TMHGHDHNVSSVAIMPN------------GDHIISASRDKTMKMWEVATGYCVKTFTGHR 234
Query 178 KW--------RGHLIA-WANNMGVKIFDIISKQRITNVPRDD 210
+W G LIA +N+ V+++ + SK+ + +
Sbjct 235 EWVRMVRPNQDGTLIASCSNDQTVRVWVVASKECKAELREHE 276
>sp|Q9EPV5|APAF_RAT Apoptotic protease-activating factor 1 OS=Rattus
norvegicus OX=10116 GN=Apaf1 PE=1 SV=1
Length=1249
Score = 36.6 bits (83), Expect = 1.3, Method: Composition-based stats.
Identities = 15/73 (21%), Positives = 31/73 (42%), Gaps = 3/73 (4%)
Query 48 ASCMTV--HDKFLALGTHYGKVYLLDVQGN-ITQKFDVSPVKINQISLDESGEHMGVCSE 104
SC + H +++A G G + ++++ N + + I G+ + SE
Sbjct 964 VSCCCLSPHLEYVAFGDEEGAIKIIELPNNRVFSSGIGHKKAVRHIQFTADGKTLISSSE 1023
Query 105 DGKVQVFGLYSGE 117
D +QV+ + E
Sbjct 1024 DSVIQVWNWQTEE 1036
>sp|Q6BZX5|SEC13_YARLI Protein transport protein SEC13 OS=Yarrowia
lipolytica (strain CLIB 122 / E 150) OX=284591 GN=SEC13
PE=3 SV=1
Length=298
Score = 35.8 bits (81), Expect = 1.4, Method: Composition-based stats.
Identities = 31/149 (21%), Positives = 61/149 (41%), Gaps = 16/149 (11%)
Query 87 INQISLDESGEHMGVCSEDGKVQVFGLYSGE-EFHETF---DCPIKIIAV-HPHFVRSSC 141
I+ LD G+ + CS D +++F + + ET + P+ ++ HP F S
Sbjct 12 IHDAVLDYYGKRLATCSSDKTIKIFEIDGDNHKLVETLRGHEGPVWQVSWAHPKFG--SI 69
Query 142 KQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKW----RGHLIAWANNMG----VK 193
+ K+ ++ R RW + H+ ++ SV W G L+ A++ G V+
Sbjct 70 IASASYDGKVFIW-REENGRWTNIAQHQHNASVNSVVWAPQEYGPLLLCASSDGNVSVVE 128
Query 194 IFDIISKQRITNVPRDDISLRPDMYPCSL 222
+ + + T D + P ++
Sbjct 129 FKEGGNCEATTFAAHDVGANSASWAPPAV 157
>sp|Q9FLX9|NLE1_ARATH Notchless protein homolog OS=Arabidopsis
thaliana OX=3702 GN=NLE1 PE=2 SV=1
Length=473
Score = 36.2 bits (82), Expect = 1.4, Method: Composition-based stats.
Identities = 36/179 (20%), Positives = 69/179 (39%), Gaps = 20/179 (11%)
Query 45 KDAASCMTVH--DKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQ-----ISLDESGE 97
+A C++ K LA G+ V L D + + + K ++ ++ G+
Sbjct 109 AEAVLCVSFSPDGKQLASGSGDTTVRLWD----LYTETPLFTCKGHKNWVLTVAWSPDGK 164
Query 98 HMGVCSEDGKVQVFGLYSGE---EFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLF 154
H+ S+ G++ + GE I I+ P + S C++FVT K
Sbjct 165 HLVSGSKSGEICCWNPKKGELEGSPLTGHKKWITGISWEPVHLSSPCRRFVTSSKDG--D 222
Query 155 ERSWMNRWKSAVLH-EGEG-NIRSVKWRGHLIAWA--NNMGVKIFDIISKQRITNVPRD 209
R W K +++ G + VKW G I + + +K+++ + I +
Sbjct 223 ARIWDITLKKSIICLSGHTLAVTCVKWGGDGIIYTGSQDCTIKMWETTQGKLIRELKGH 281
>sp|Q6NVM2|KTNB1_XENTR Katanin p80 WD40 repeat-containing subunit
B1 OS=Xenopus tropicalis OX=8364 GN=katnb1 PE=2 SV=1
Length=655
Score = 36.2 bits (82), Expect = 1.4, Method: Composition-based stats.
Identities = 22/102 (22%), Positives = 43/102 (42%), Gaps = 7/102 (7%)
Query 40 TEILQKDAASCMTVH--DKFLALGTHYGKVYLLDV--QGNITQKFDVSPVKINQISLDES 95
T + K + H F+A G+ + L DV +G + + + + +
Sbjct 100 TLMGHKANVCSLDFHPYGDFVASGSLDTNIKLWDVRRKGCVFR-YKGHTQAVRCLRFSPD 158
Query 96 GEHMGVCSEDGKVQVFGLYSGEEFHE--TFDCPIKIIAVHPH 135
G+ + S+D V+++ L +G+ E P+ II HP+
Sbjct 159 GKWLASASDDHSVKLWDLTAGKMMAELSEHKGPVNIIEFHPN 200
>sp|Q6ZJW8|FIE1_ORYSJ Polycomb group protein FIE1 OS=Oryza sativa
subsp. japonica OX=39947 GN=FIE1 PE=1 SV=1
Length=466
Score = 36.2 bits (82), Expect = 1.4, Method: Composition-based stats.
Identities = 30/116 (26%), Positives = 46/116 (40%), Gaps = 16/116 (14%)
Query 1 MAEAEEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEI---LQKDAASCMTVHDKF 57
++++ E E E T E E + KY V E K H
Sbjct 340 LSKSVENEILLWESITKEENPGEGHIDVLQKYP-----VPECNIWFMK---FSCDFHHNQ 391
Query 58 LALGTHYGKVYLLDVQGN---ITQKFDVSPVK--INQISLDESGEHMGVCSEDGKV 108
LA+G GKVY+ VQ + + + + VK I Q ++ G + C+EDG +
Sbjct 392 LAIGNRDGKVYVWKVQTSPPVLIARLNNPQVKSAIRQTAVSFDGSTILACTEDGNI 447
>sp|Q9USL1|THOC3_SCHPO THO complex subunit Tho3 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=THO3 PE=3
SV=1
Length=309
Score = 35.8 bits (81), Expect = 1.4, Method: Composition-based stats.
Identities = 18/90 (20%), Positives = 37/90 (41%), Gaps = 6/90 (7%)
Query 50 CMTVH--DKFLALGTHYGKVYLLDVQGNITQKFDVSPV--KINQISLDESGEHMGVCSED 105
C+ ++ LA+G L D Q + + ++ + I +S ++ SED
Sbjct 199 CIEFSPDNRHLAIGGADAITSLWDPQ-ELICERSITRMDYPIRTLSFSYDSRYLASGSED 257
Query 106 GKVQVFGLYSGEEF-HETFDCPIKIIAVHP 134
V + +G++ + P+ +A HP
Sbjct 258 RYVDIADTKTGDQIWKIPTNGPLNKVAWHP 287
>sp|Q0CHM0|SEC13_ASPTN Protein transport protein sec13 OS=Aspergillus
terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=sec13
PE=3 SV=1
Length=309
Score = 35.8 bits (81), Expect = 1.5, Method: Composition-based stats.
Identities = 60/257 (23%), Positives = 91/257 (35%), Gaps = 50/257 (19%)
Query 33 ERLSNGVTEILQKDAASCMT-VHDKF---LALGTHYGKVYLL-DVQGNITQ--------- 78
RL + + A C+ H KF LA ++ GKV + + N T
Sbjct 47 HRLVETLKG--HEGAVWCVAWAHPKFGTILASSSYDGKVLIWREQHQNTTSPAAGSAWTK 104
Query 79 --KFDVSPVKINQISL--DESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCP---IKIIA 131
F + +N +S ESG +G S DG V V H+ F + I+
Sbjct 105 VFDFSLHTASVNMVSWAPHESGCLLGCASSDGHVSVLEFQDNSWTHQIFHAHGMGVNSIS 164
Query 132 VHPHFVRSS----------CKQFVTGGKKLLLFERSWMNRWKSAVL-HEGEGN---IRSV 177
P S ++FVTGG LL + K+ L EG+ +R V
Sbjct 165 WAPAAAPGSLISANPGPGQQRRFVTGGSDNLLKIWDYNPETKTYNLSQTLEGHSDWVRDV 224
Query 178 KW-----RGHLIAWAN-NMGVKIF--DIISKQRITNVPRDDISLRPDMYPCSLCWKDNVT 229
W IA A+ + V+I+ D + + T+ L D + W +
Sbjct 225 AWSPSILSKSYIASASQDKTVRIWTSDASNPGQWTS-----QQLEFDSVLWRVSWSPSGN 279
Query 230 LIIGWGTSVKVCSVKER 246
++ G KV KE
Sbjct 280 ILAVSGGDNKVSLWKEN 296
>sp|Q0CQ54|HIR1_ASPTN Protein hir1 OS=Aspergillus terreus (strain
NIH 2624 / FGSC A1156) OX=341663 GN=hir1 PE=3 SV=1
Length=999
Score = 36.2 bits (82), Expect = 1.5, Method: Composition-based stats.
Identities = 11/74 (15%), Positives = 25/74 (34%), Gaps = 5/74 (7%)
Query 76 ITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCP-----IKII 130
I+ + +G+++ ++D V ++ L + H TF + +
Sbjct 84 QLASMSNHSGTIHTVRFSPNGKYLASGADDKIVCIYTLDANPPSHSTFGWSYDSSILVSV 143
Query 131 AVHPHFVRSSCKQF 144
+ V S F
Sbjct 144 GLDSKVVVWSGHTF 157
>sp|B3MC74|CIAO1_DROAN Probable cytosolic iron-sulfur protein
assembly protein Ciao1 OS=Drosophila ananassae OX=7217 GN=Ciao1
PE=3 SV=1
Length=335
Score = 35.8 bits (81), Expect = 1.7, Method: Composition-based stats.
Identities = 23/134 (17%), Positives = 43/134 (32%), Gaps = 28/134 (21%)
Query 70 LDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKI 129
LD + + I D +GE + CS+D ++++ Y
Sbjct 180 LDSDWDCVATLSSHTSTVWSIDFDATGERLVSCSDDTSLKIWQAYHPGNDA--------G 231
Query 130 IAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWA-N 188
+A C ++G +++ SW +LIA A
Sbjct 232 VATPDKQTVWKCVCTISGQHSRAIYDVSW-------------------CKLTNLIATACG 272
Query 189 NMGVKIFDIISKQR 202
+ G++IF S +
Sbjct 273 DDGIRIFKETSDSK 286
>sp|P54686|AIP1_DICDI Actin-interacting protein 1 OS=Dictyostelium
discoideum OX=44689 GN=aip1 PE=1 SV=2
Length=597
Score = 36.2 bits (82), Expect = 1.7, Method: Composition-based stats.
Identities = 14/91 (15%), Positives = 33/91 (36%), Gaps = 4/91 (4%)
Query 49 SCMTVHDKFLALGTHYGKVYLLDVQGNITQK---FDVSPVKINQISLDESGEHMGV-CSE 104
+ + ++D +++G K+++ + GN D I +S G+++ CS
Sbjct 444 TSVAINDTEVSVGGKDNKIHVFTLSGNNLTASHTLDNHRGAITDLSYSPCGKYLASGCSN 503
Query 105 DGKVQVFGLYSGEEFHETFDCPIKIIAVHPH 135
+ G + + I +A
Sbjct 504 REVIVWSGKEAKSKGWVNHTARINAVAWSND 534
>sp|B0X2V9|WDR48_CULQU WD repeat-containing protein 48 homolog
OS=Culex quinquefasciatus OX=7176 GN=CPIJ014111 PE=3 SV=1
Length=670
Score = 36.2 bits (82), Expect = 1.7, Method: Composition-based stats.
Identities = 24/148 (16%), Positives = 56/148 (38%), Gaps = 22/148 (15%)
Query 44 QKDAASCMTV--HDKFLALGTHYGKVYLLDVQG-NITQKFDVSPVKINQISLDESGEHMG 100
KD+ + + + G+ + + D + N K + + + E G +
Sbjct 153 SKDSIYSLAMNPSGTIIVSGSTENTLRIWDPRTCNKIAKLKGHTENVKALVVSEDGTQVV 212
Query 101 VCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPH-----FVRSSCKQFVTG--GKKLLL 153
S DGK++++ + I+ I+VH + + ++G KK+++
Sbjct 213 SGSSDGKIKLWSIGQ--------QRCIQTISVHSEGVWALLMTDNFSHVISGSRDKKIVM 264
Query 154 FERSWMNRWKSAVL-HEGEGNIRSVKWR 180
E + ++VL E + S+ +
Sbjct 265 TE---LRNPTNSVLICEERAPVLSLCYN 289
>sp|A5DNK9|IPI3_PICGU Pre-rRNA-processing protein IPI3 OS=Meyerozyma
guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381
/ JCM 1539 / NBRC 10279 / NRRL Y-324) OX=294746 GN=IPI3 PE=3
SV=2
Length=451
Score = 35.8 bits (81), Expect = 1.7, Method: Composition-based stats.
Identities = 14/55 (25%), Positives = 25/55 (45%), Gaps = 1/55 (2%)
Query 57 FLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQV 110
LA G+ GK+Y+ ++ GN+ + IN + E G ++ D + V
Sbjct 106 LLAGGSASGKLYIWELSSGNLVCVKEAHYQAINVLKFSECGTYLVSGGADARCSV 160
>sp|Q8BHJ5|TBL1R_MOUSE F-box-like/WD repeat-containing protein
TBL1XR1 OS=Mus musculus OX=10090 GN=Tbl1xr1 PE=1 SV=1
Length=514
Score = 35.8 bits (81), Expect = 1.7, Method: Composition-based stats.
Identities = 12/60 (20%), Positives = 25/60 (42%), Gaps = 2/60 (3%)
Query 77 TQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH--ETFDCPIKIIAVHP 134
+ F ++N I D +G + CS+D ++++ + H + + I I P
Sbjct 342 IKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSP 401
>sp|Q9BZK7|TBL1R_HUMAN F-box-like/WD repeat-containing protein
TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1
Length=514
Score = 35.8 bits (81), Expect = 1.7, Method: Composition-based stats.
Identities = 12/60 (20%), Positives = 25/60 (42%), Gaps = 2/60 (3%)
Query 77 TQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH--ETFDCPIKIIAVHP 134
+ F ++N I D +G + CS+D ++++ + H + + I I P
Sbjct 342 IKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSP 401
>sp|Q9H920|RN121_HUMAN E3 ubiquitin ligase RNF121 OS=Homo sapiens
OX=9606 GN=RNF121 PE=1 SV=1
Length=327
Score = 35.8 bits (81), Expect = 1.8, Method: Composition-based stats.
Identities = 14/78 (18%), Positives = 27/78 (35%), Gaps = 2/78 (3%)
Query 766 ADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPF--SVVVFHCRHMFHKECL 823
AD ++ + +++C C I + + + C H+FH+ C+
Sbjct 201 ADYMASTIGFYSESGMPTKHLSDSVCAVCGQQIFVDVSEEGIIENTYRLSCNHVFHEFCI 260
Query 824 PMPSMNSAAQFCNICSAK 841
+ Q C C K
Sbjct 261 RGWCIVGKKQTCPYCKEK 278
>sp|B6IST2|LEXA_RHOCS LexA repressor OS=Rhodospirillum centenum
(strain ATCC 51521 / SW) OX=414684 GN=lexA PE=3 SV=1
Length=237
Score = 35.5 bits (80), Expect = 1.8, Method: Composition-based stats.
Identities = 24/115 (21%), Positives = 42/115 (37%), Gaps = 15/115 (13%)
Query 32 YERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQIS 91
Y R++ G+ +D + + V +A G H Y L+V G+ ++
Sbjct 118 YGRIAAGLPIEALRDTTASIDVPTGLIASGEH----YALEVAGDSM---------VDAGI 164
Query 92 LDESGEHMGVC--SEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQF 144
LD + C +E+G V V + E + IA+ P + F
Sbjct 165 LDGDTVIIQRCETAENGTVIVALVDDNEVTLKRLRRKGNSIALEPANPAYETRVF 219
>sp|Q54RP0|AGTA_DICDI UDP-galactose:fucoside alpha-3-galactosyltransferase
OS=Dictyostelium discoideum OX=44689 GN=agtA PE=1
SV=1
Length=648
Score = 35.8 bits (81), Expect = 1.8, Method: Composition-based stats.
Identities = 17/88 (19%), Positives = 33/88 (38%), Gaps = 0/88 (0%)
Query 26 EEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPV 85
+ K ++R T I + + + L +H + D + Q F
Sbjct 366 LKSKYIHKRGGIWSTFIFSSNNNNNNDYGFENLLTSSHDKTIQYWDNNLQVIQTFIGHTG 425
Query 86 KINQISLDESGEHMGVCSEDGKVQVFGL 113
INQ+ + + + CS+D ++ F L
Sbjct 426 IINQLIVIPNSSYFFTCSDDNTIRQFDL 453
>sp|Q75CC8|HRD1_EREGS ERAD-associated E3 ubiquitin-protein ligase
HRD1 OS=Eremothecium gossypii (strain ATCC 10895 / CBS 109.51
/ FGSC 9923 / NRRL Y-1056) OX=284811 GN=HRD1 PE=3 SV=2
Length=575
Score = 35.8 bits (81), Expect = 1.9, Method: Composition-based stats.
Identities = 16/55 (29%), Positives = 24/55 (44%), Gaps = 4/55 (7%)
Query 786 DEENICESCLSPILPSDAAKPFS--VVVFHCRHMFHKECLPMPSMNSAAQFCNIC 838
D +++C C+ +LP+ + + C HM H CL S Q C IC
Sbjct 315 DTDSMCIICMDDMLPTTETTKMNRRAKMLPCGHMLHFGCLKSWMERS--QTCPIC 367
>sp|O55176|PJA1_MOUSE E3 ubiquitin-protein ligase Praja-1 OS=Mus
musculus OX=10090 GN=Pja1 PE=1 SV=3
Length=578
Score = 35.8 bits (81), Expect = 1.9, Method: Composition-based stats.
Identities = 35/150 (23%), Positives = 55/150 (37%), Gaps = 13/150 (9%)
Query 690 QDDGELWEDLILYSIDKPPFITGL-LNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQ 748
+DD + EDL + F GL + ++VDP L + E L ++ L
Sbjct 433 EDDSSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALE----ERLAQAMETALA 488
Query 749 DYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFS 808
+ E +S+ L ++ T+ G V +E C C S+ K
Sbjct 489 HLESLAVDVEVANPPASKESIDALPEILVTEDHG-AVGQEMCCPIC-----CSEYVKGEV 542
Query 809 VVVFHCRHMFHKECLPMPSMNSAAQFCNIC 838
C H FHK C+ + S C +C
Sbjct 543 ATELPCHHYFHKPCVSIWLQKSGT--CPVC 570
>sp|G5ECZ4|DYF2_CAEEL WD repeat-containing protein dyf-2 OS=Caenorhabditis
elegans OX=6239 GN=dyf-2 PE=1 SV=1
Length=1383
Score = 36.2 bits (82), Expect = 1.9, Method: Composition-based stats.
Identities = 26/145 (18%), Positives = 51/145 (35%), Gaps = 17/145 (12%)
Query 58 LALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSG 116
L +G + G + + + + + QI++ +++ CS+D + V L
Sbjct 135 LVIGNNAGNIVVYNHRTSRRIAVMGKHQRSVTQITVTPE-DYVISCSDDNTLSVTTLEGT 193
Query 117 EEFHETFD-CPIKIIAVHPHFVRSSCK--------QFVTGGKKLLLFERSWMNRWKSAVL 167
T + P + + + K V G K L+L + ++ +
Sbjct 194 TVSTTTTNGEPTNM-----DYGSVNGKGGSGVTMVSVVIGKKILMLAHYNALDEPVNLQF 248
Query 168 HEGEGNIRSVKW-RGHLIAWANNMG 191
E GNI S +W I + G
Sbjct 249 QEKYGNIHSYRWFNDGYILIGFDRG 273
>sp|O13046|WDHD1_XENLA WD repeat and HMG-box DNA-binding protein
1 OS=Xenopus laevis OX=8355 GN=wdhd1 PE=1 SV=1
Length=1127
Score = 36.2 bits (82), Expect = 1.9, Method: Composition-based stats.
Identities = 35/217 (16%), Positives = 77/217 (35%), Gaps = 29/217 (13%)
Query 24 SEEEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQK-FDV 82
+ EP R + ++ + +A G+ V +L V+ + QK
Sbjct 82 PDGEPDGILTRFTTNANHVVFNTDGTR-------IAAGSGDFLVKVLQVEDSTQQKTLRG 134
Query 83 SPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCK 142
+ +S D ++ S DG V+++ + ++ E P+ +S C+
Sbjct 135 HSAPVLSVSFDPKDIYLASASCDGSVRIWKI--SDQTCEAV-LPLLEKCNDVFNAKSICR 191
Query 143 --------QFVT--GGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR---GHLIAWANN 189
+FV GK + L++R + + + V W +L+A + +
Sbjct 192 LAWQPKSGKFVAIPVGKAVHLYDRDSLKNICTLSDDFITQPVNIVAWSPCGQYLVAGSVD 251
Query 190 MGVKIFDIISKQRITNVPRDDISLRPDMYPCSLCWKD 226
+ ++I +K + + + C+L W
Sbjct 252 GCIVAWNIATKACLERIKHEKGYT-----ICALAWHP 283
>sp|Q4R4I8|COPB2_MACFA Coatomer subunit beta' OS=Macaca fascicularis
OX=9541 GN=COPB2 PE=2 SV=1
Length=906
Score = 35.8 bits (81), Expect = 1.9, Method: Composition-based stats.
Identities = 35/224 (16%), Positives = 77/224 (34%), Gaps = 20/224 (9%)
Query 34 RLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
RL + D + +H + ++ + G V + + + + F+V + +
Sbjct 4 RLDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAA 63
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFH--ETFDCPIKIIAVHPHFVRSSCKQFVTGG 148
+ ++D +++VF + E H E I+ IAVHP + +T
Sbjct 64 KFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHP-----TQPFILTSS 118
Query 149 KKLLLFERSWMNRWKSAVLHEGEG-NIRSV----KWRGHLIAWANNMGVKIFDIISKQRI 203
+L+ W +W + + EG + + K + + + +K++ + S
Sbjct 119 DDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPN 178
Query 204 TNVPRDD-----ISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCS 242
+ + I L + L+ W K C
Sbjct 179 FTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCV 222
>sp|Q9C1X4|YKW3_SCHPO Uncharacterized RING finger protein P32A8.03c
OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843)
OX=284812 GN=SPAP32A8.03c PE=4 SV=1
Length=513
Score = 35.8 bits (81), Expect = 1.9, Method: Composition-based stats.
Identities = 19/70 (27%), Positives = 30/70 (43%), Gaps = 7/70 (10%)
Query 771 LLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNS 830
++ KM + L+DEE C C+ +D V+ C+H FH+ C+ +
Sbjct 376 VIAKMKVQKPPKELIDEEGECTICMEMFKINDD-----VIQLPCKHYFHENCIKPWLRVN 430
Query 831 AAQFCNICSA 840
C IC A
Sbjct 431 GT--CAICRA 438
>sp|Q9FF61|SM3L1_ARATH Putative SWI/SNF-related matrix-associated
actin-dependent regulator of chromatin subfamily A member
3-like 1 OS=Arabidopsis thaliana OX=3702 GN=At5g05130 PE=2
SV=1
Length=881
Score = 35.8 bits (81), Expect = 2.0, Method: Composition-based stats.
Identities = 27/130 (21%), Positives = 52/130 (40%), Gaps = 29/130 (22%)
Query 711 TGLLNNIGTHVDPILLIHRIKEGMEI--PNLRDSLVKILQDYNLQILLREGCKKILVADS 768
L+ N T + IL + ++ + M + P LR + + + V D
Sbjct 571 GSLMRNYSTVLSIILRLRQLCDDMSLCPPELRS--------FTTSTSVED------VTDK 616
Query 769 LSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSM 828
LL+K+ G D C C+SP P ++++ C H+F + C+ + ++
Sbjct 617 PELLQKLVAALQDGEDFD----CPICISP--------PTNIIITRCAHIFCRACI-LQTL 663
Query 829 NSAAQFCNIC 838
+ C +C
Sbjct 664 QRSKPLCPLC 673
>sp|Q9QXE7|TBL1X_MOUSE F-box-like/WD repeat-containing protein
TBL1X OS=Mus musculus OX=10090 GN=Tbl1x PE=1 SV=2
Length=527
Score = 35.8 bits (81), Expect = 2.0, Method: Composition-based stats.
Identities = 25/179 (14%), Positives = 58/179 (32%), Gaps = 10/179 (6%)
Query 36 SNGVTEILQKDAASCMTVHD-KFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDE 94
G KD S D LA G++ G + GN+ I + ++
Sbjct 230 EGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNK 289
Query 95 SGEHMGVCSEDGKVQVFGLYSGE-EFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLL 153
G ++ D ++ ++GE + F A+ + + F + + +
Sbjct 290 KGNYILSAGVDKTTIIWDAHTGEAKQQFPFH---SAPALDVDW--QNNTTFASCSTDMCI 344
Query 154 FERSWMNRWKSAVLHEGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRITNVPRD 209
+ ++KW L + +++M +KI+ + + ++
Sbjct 345 HVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAH 403
>sp|B4LJT7|CIAO1_DROVI Probable cytosolic iron-sulfur protein
assembly protein Ciao1 OS=Drosophila virilis OX=7244 GN=Ciao1
PE=3 SV=1
Length=331
Score = 35.5 bits (80), Expect = 2.0, Method: Composition-based stats.
Identities = 25/134 (19%), Positives = 43/134 (32%), Gaps = 28/134 (21%)
Query 70 LDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKI 129
LD + T + I D GE + CS+D ++++ Y
Sbjct 176 LDSDWDCTATLSSHTSTVWSIDFDADGERLVSCSDDATLKIWRAYHPGNDA--------G 227
Query 130 IAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWA-N 188
IA C ++G +++ SW + LIA A
Sbjct 228 IATPDKTTVWKCVCTLSGEHSRAIYDVSWCKQ-------------------TGLIASACG 268
Query 189 NMGVKIFDIISKQR 202
+ G++IF S +
Sbjct 269 DDGIRIFKECSDSK 282
>sp|B4QFZ8|CIAO1_DROSI Probable cytosolic iron-sulfur protein
assembly protein Ciao1 OS=Drosophila simulans OX=7240 GN=Ciao1
PE=3 SV=1
Length=335
Score = 35.5 bits (80), Expect = 2.0, Method: Composition-based stats.
Identities = 24/134 (18%), Positives = 42/134 (31%), Gaps = 28/134 (21%)
Query 70 LDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKI 129
+D + T + I D GE + CS+D ++++ Y
Sbjct 180 IDNDWDCTATLTSHTSTVWGIDFDADGERLVSCSDDTTIKIWKAYHPGNTA--------G 231
Query 130 IAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWA-N 188
+A C V+G +++ SW LIA A
Sbjct 232 VATPEQQTVWKCVCTVSGQHSRAIYDVSW-------------------CKLTGLIATACG 272
Query 189 NMGVKIFDIISKQR 202
+ G++IF S +
Sbjct 273 DDGIRIFKETSDSK 286
>sp|Q6S7B0|TAF5_ARATH Transcription initiation factor TFIID subunit
5 OS=Arabidopsis thaliana OX=3702 GN=TAF5 PE=1 SV=1
Length=669
Score = 35.8 bits (81), Expect = 2.0, Method: Composition-based stats.
Identities = 15/60 (25%), Positives = 28/60 (47%), Gaps = 1/60 (2%)
Query 57 FLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYS 115
++A G+ V L DVQ G + F + +++ G +M EDG + ++ L +
Sbjct 516 YIATGSSDKTVRLWDVQTGECVRIFIGHRSMVLSLAMSPDGRYMASGDEDGTIMMWDLST 575
>sp|Q68FJ6|PK1IP_XENLA p21-activated protein kinase-interacting
protein 1-like OS=Xenopus laevis OX=8355 GN=pak1ip1 PE=2 SV=1
Length=363
Score = 35.5 bits (80), Expect = 2.0, Method: Composition-based stats.
Identities = 31/183 (17%), Positives = 69/183 (38%), Gaps = 18/183 (10%)
Query 36 SNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQISLDE 94
S T + S + V+++F+A G+ + + D++ + I +
Sbjct 31 SADFTHHAHTASVSVLAVNNRFVATGSRDETIQIYDMKKKVEHGALLHHNGTITCLEF-Y 89
Query 95 SGEHMGVCSEDGKVQVFGLYSGEEFHETFDC---PIKIIAVHPHFVRSSCKQFVTGGKKL 151
H+ +EDG + V+ E +TF + +++HP S K ++ G
Sbjct 90 GNTHLLSGAEDGLICVWN-TKKWECQQTFKAHKGQVLSLSIHP-----SGKLALSVGTDK 143
Query 152 LLFERSW-MNRWKSAVLHEGEGNIRSVKWR---GHLIAWANNMGVKIFDIISKQRITNVP 207
L R+W + +SA + + N V W + ++ V ++ + + + +
Sbjct 144 TL--RTWNLVEGRSAFIKNIKKNAHIVHWSPSGEKYVVVIHDT-VDVYQLETAAVVGTIN 200
Query 208 RDD 210
Sbjct 201 NPK 203
>sp|P35605|COPB2_BOVIN Coatomer subunit beta' OS=Bos taurus OX=9913
GN=COPB2 PE=1 SV=3
Length=906
Score = 35.8 bits (81), Expect = 2.0, Method: Composition-based stats.
Identities = 35/224 (16%), Positives = 77/224 (34%), Gaps = 20/224 (9%)
Query 34 RLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
RL + D + +H + ++ + G V + + + + F+V + +
Sbjct 4 RLDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAA 63
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFH--ETFDCPIKIIAVHPHFVRSSCKQFVTGG 148
+ ++D +++VF + E H E I+ IAVHP + +T
Sbjct 64 KFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHP-----TQPFILTSS 118
Query 149 KKLLLFERSWMNRWKSAVLHEGEG-NIRSV----KWRGHLIAWANNMGVKIFDIISKQRI 203
+L+ W +W + + EG + + K + + + +K++ + S
Sbjct 119 DDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPN 178
Query 204 TNVPRDD-----ISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCS 242
+ + I L + L+ W K C
Sbjct 179 FTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCV 222
>sp|Q11176|WDR1_CAEEL Actin-interacting protein 1 OS=Caenorhabditis
elegans OX=6239 GN=unc-78 PE=1 SV=1
Length=611
Score = 35.8 bits (81), Expect = 2.0, Method: Composition-based stats.
Identities = 22/111 (20%), Positives = 46/111 (41%), Gaps = 9/111 (8%)
Query 37 NGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQGNITQKF--DVSPVKINQISL 92
+TE+ +SC+ + +F+A+G KV++ + G + V P +I ++
Sbjct 440 GKLTEVPISYNSSCVALSNDKQFVAVGGQDSKVHVYKLSGASVSEVKTIVHPAEITSVAF 499
Query 93 DESGEHMGVCSEDGKVQVFGLYSGEEFHE----TFDC-PIKIIAVHPHFVR 138
+G + + KV + + + E TF + ++ P VR
Sbjct 500 SNNGAFLVATDQSRKVIPYSVANNFELAHTNSWTFHTAKVACVSWSPDNVR 550
>sp|Q5R664|COPB2_PONAB Coatomer subunit beta' OS=Pongo abelii
OX=9601 GN=COPB2 PE=2 SV=1
Length=906
Score = 35.8 bits (81), Expect = 2.1, Method: Composition-based stats.
Identities = 35/224 (16%), Positives = 77/224 (34%), Gaps = 20/224 (9%)
Query 34 RLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
RL + D + +H + ++ + G V + + + + F+V + +
Sbjct 4 RLDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAA 63
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFH--ETFDCPIKIIAVHPHFVRSSCKQFVTGG 148
+ ++D +++VF + E H E I+ IAVHP + +T
Sbjct 64 KFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHP-----TQPFILTSS 118
Query 149 KKLLLFERSWMNRWKSAVLHEGEG-NIRSV----KWRGHLIAWANNMGVKIFDIISKQRI 203
+L+ W +W + + EG + + K + + + +K++ + S
Sbjct 119 DDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPN 178
Query 204 TNVPRDD-----ISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCS 242
+ + I L + L+ W K C
Sbjct 179 FTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCV 222
>sp|A2CEH0|POC1B_DANRE POC1 centriolar protein homolog B OS=Danio
rerio OX=7955 GN=poc1b PE=2 SV=1
Length=490
Score = 35.8 bits (81), Expect = 2.1, Method: Composition-based stats.
Identities = 17/96 (18%), Positives = 34/96 (35%), Gaps = 8/96 (8%)
Query 58 LALGTHYGKVYLLDVQGN-ITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSG 116
+A + + D++ N + Q + V +N S SG ++ S D +++ L G
Sbjct 201 IASSGADNTIKIWDIRTNKLIQHYKVHNAGVNCFSFHPSGNYLISGSSDSTIKILDLLEG 260
Query 117 EEFH--ETFDCPIKIIAVHPHFVRSSCKQFVTGGKK 150
+ P+ + F +GG
Sbjct 261 RLIYTLHGHKGPVLTVTFSRD-----GDLFASGGAD 291
>sp|O54880|RPH3L_RAT Rab effector Noc2 OS=Rattus norvegicus OX=10116
GN=Rph3al PE=1 SV=1
Length=302
Score = 35.5 bits (80), Expect = 2.1, Method: Composition-based stats.
Identities = 20/93 (22%), Positives = 32/93 (34%), Gaps = 5/93 (5%)
Query 752 LQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVV 811
LQ++ R IL + L + T K V+ + + C C + ++ F
Sbjct 56 LQVIQRAERLDILEQQRIGRLVERLETMQKNVMGNGVSQCLLCGEMLGFLGSSSVFCK-- 113
Query 812 FHCRHMFHKEC--LPMPSMNSAAQFCNICSAKN 842
CR +C P C ICS +
Sbjct 114 -DCRKKVCTKCGIEASPGQKRPLWLCKICSEQR 145
>sp|D5GBI7|LIS1_TUBMM Nuclear distribution protein PAC1 OS=Tuber
melanosporum (strain Mel28) OX=656061 GN=PAC1 PE=3 SV=1
Length=452
Score = 35.5 bits (80), Expect = 2.1, Method: Composition-based stats.
Identities = 13/71 (18%), Positives = 31/71 (44%), Gaps = 0/71 (0%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
+F+A G+ + L D +G + + I ++ +G+++ S+D ++ + L
Sbjct 324 SSEFIATGSRDKTIKLWDARGTLLKTLVGHDNWIRALAFHPAGKYLLSVSDDKTIRCWDL 383
Query 114 YSGEEFHETFD 124
+T D
Sbjct 384 TQDGRCVKTVD 394
>sp|Q5VQ78|COB21_ORYSJ Coatomer subunit beta'-1 OS=Oryza sativa
subsp. japonica OX=39947 GN=Os06g0143900 PE=2 SV=1
Length=907
Score = 35.8 bits (81), Expect = 2.2, Method: Composition-based stats.
Identities = 25/133 (19%), Positives = 55/133 (41%), Gaps = 10/133 (8%)
Query 34 RLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
RL + + + +H + ++ + G V + D Q + F+VS + +
Sbjct 4 RLEIKRKFAQRSERVKSVDLHPTEPWILSSLYSGSVCIWDYQSQTMVKSFEVSELPVRSA 63
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFH--ETFDCPIKIIAVHPH--FVRSSCKQFVT 146
+ + ++D ++V+ + ++ E I+ +AVHP +V SS +
Sbjct 64 KFISRKQWVVAGADDMFIRVYNYNTMDKVKVFEAHTDYIRCVAVHPTLPYVLSSSDDMLI 123
Query 147 GGKKLLLFERSWM 159
KL +++ WM
Sbjct 124 ---KLWDWDKGWM 133
>sp|B8P4B0|LIS11_POSPM Nuclear distribution protein PAC1-1 OS=Postia
placenta (strain ATCC 44394 / Madison 698-R) OX=561896
GN=PAC1-1 PE=3 SV=1
Length=438
Score = 35.5 bits (80), Expect = 2.2, Method: Composition-based stats.
Identities = 18/83 (22%), Positives = 35/83 (42%), Gaps = 9/83 (11%)
Query 57 FLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYS 115
++A G+ V + DV G + I + SG+H+ S+D ++V+ L +
Sbjct 313 YIATGSRDKTVKIWDVHSGQELRTLSGHNDWIRGLVFHPSGKHLLSASDDKTIRVWELST 372
Query 116 GEEFHETFDCPIKIIAVHPHFVR 138
+K++ H HF+
Sbjct 373 --------GRCMKVVEAHSHFIT 387
Score = 34.7 bits (78), Expect = 4.3, Method: Composition-based stats.
Identities = 13/66 (20%), Positives = 26/66 (39%), Gaps = 3/66 (5%)
Query 48 ASCMTVHDKF--LALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSE 104
+ + H F LA + V + D + G+ + ++ + D G + CS
Sbjct 111 ITRVAFHPTFSLLASASEDTTVKIWDWETGSFERTLKGHTREVWGVDFDSKGSFLATCSS 170
Query 105 DGKVQV 110
D ++V
Sbjct 171 DLSIKV 176
>sp|Q6PAX7|WDR1B_XENLA WD repeat-containing protein 1-B OS=Xenopus
laevis OX=8355 GN=wdr1-b PE=2 SV=1
Length=607
Score = 35.8 bits (81), Expect = 2.2, Method: Composition-based stats.
Identities = 19/104 (18%), Positives = 42/104 (40%), Gaps = 13/104 (13%)
Query 58 LALGTHYGKVYLLDVQGNITQKFDVSPVK----INQISLDESGEHMGVCSEDGKVQVFGL 113
+++G GKV+L +QGN + + + + ++ G + V + V VF +
Sbjct 460 VSVGGADGKVHLYSIQGNSLKD-EGKTLPAKGAVTDLAYSPDGAFLAVTDANKVVTVFSV 518
Query 114 YSGEEFHETF---DCPIKIIAVHPHFVRSSCKQFVTGGKKLLLF 154
G H ++ +A P + F + G ++++
Sbjct 519 ADGYSEHNSYYGHHAKALSVAWSPD-----NEHFASSGMDMMVY 557
>sp|B6QC06|LIS12_TALMQ Nuclear distribution protein nudF 2 OS=Talaromyces
marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333)
OX=441960 GN=nudF-2 PE=3 SV=1
Length=452
Score = 35.5 bits (80), Expect = 2.3, Method: Composition-based stats.
Identities = 26/177 (15%), Positives = 63/177 (36%), Gaps = 15/177 (8%)
Query 45 KDAASCMTVHDKF--LALGTHYGKVYLLD-VQGNITQKFDVSPVKINQISLDESGEH--M 99
+DA +C+ H F LA + + + D G + + + + + +
Sbjct 125 RDAITCIAFHPIFTSLASSSEDCTIKIWDWELGELERTLKGHIRAVTGLDFGGQKGNTLL 184
Query 100 GVCSEDGKVQV---FGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER 156
CS D V++ Y+ D + + F+ S+ V+ G+ +
Sbjct 185 ASCSSDLTVKLWDPSKGYANIRTLSGHDHSVSAV----RFLTSTENLLVSAGRDASIRIW 240
Query 157 SWMNRWKSAVLHEGEGNIRSVKWRGH---LIAWANNMGVKIFDIISKQRITNVPRDD 210
+ VL + IR + L+A + V ++++ + ++ + + +
Sbjct 241 DVSTGYCVKVLRSSDAWIRDISSSFDGKWLVAGGRDQAVTVWEVATAEQKSALLGHE 297
>sp|Q7K1Y4|CIAO1_DROME Probable cytosolic iron-sulfur protein
assembly protein Ciao1 OS=Drosophila melanogaster OX=7227 GN=Ciao1
PE=1 SV=1
Length=335
Score = 35.5 bits (80), Expect = 2.3, Method: Composition-based stats.
Identities = 24/134 (18%), Positives = 42/134 (31%), Gaps = 28/134 (21%)
Query 70 LDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKI 129
+D + T + I D GE + CS+D ++++ Y
Sbjct 180 IDNDWDCTATLTSHTSTVWGIDFDADGERLVSCSDDTTIKIWRAYHPGNTA--------G 231
Query 130 IAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWA-N 188
+A C V+G +++ SW LIA A
Sbjct 232 VATPDQQTVWKCVCTVSGQHSRAIYDVSW-------------------CKLTGLIATACG 272
Query 189 NMGVKIFDIISKQR 202
+ G++IF S +
Sbjct 273 DDGIRIFKESSDSK 286
>sp|B6K1G6|CFD1_SCHJY Probable cytosolic Fe-S cluster assembly
factor SJAG_02895 OS=Schizosaccharomyces japonicus (strain
yFS275 / FY16936) OX=402676 GN=SJAG_02895 PE=3 SV=2
Length=612
Score = 35.5 bits (80), Expect = 2.3, Method: Composition-based stats.
Identities = 15/85 (18%), Positives = 31/85 (36%), Gaps = 8/85 (9%)
Query 58 LALGTHYGKVYLL---DVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
LA+ + V + D + ++ ++ G ++ CS D V ++
Sbjct 348 LAIASFDATVSIYEKIDDDWECVAALEGHENEVKCVAWSHDGVYLATCSRDKSVWIWEAM 407
Query 115 SGEEFHE-----TFDCPIKIIAVHP 134
+EF +K++A HP
Sbjct 408 EDDEFDCLAVLQEHTQDVKVVAWHP 432
>sp|P62884|GBLP_LEIIN Small ribosomal subunit protein RACK1 OS=Leishmania
infantum OX=5671 GN=LACK1 PE=2 SV=1
Length=312
Score = 35.1 bits (79), Expect = 2.3, Method: Composition-based stats.
Identities = 24/148 (16%), Positives = 54/148 (36%), Gaps = 19/148 (13%)
Query 61 GTHYGKVYLLDVQGNIT-QKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEE- 118
G+ + + +V G + ++ +++ G +DG ++ L +GE+
Sbjct 170 GSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDLSTGEQL 229
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQF---VTGGKKLLLFERSWMNRWKSAVLHEGEGNIR 175
F + PI IA P+ +F V + L +++ + + +G
Sbjct 230 FKINVESPINQIAFSPN-------RFWMCVATERSLSVYDLES-KAVIAELTPDGAKPSE 281
Query 176 SVKWRGHLIAWANNMGVKIFDIISKQRI 203
+ IAW+ + G ++ I
Sbjct 282 CIS-----IAWSAD-GNTLYSGHKDNLI 303
>sp|P62883|GBLP_LEICH Small ribosomal subunit protein RACK1 OS=Leishmania
chagasi OX=44271 PE=2 SV=1
Length=312
Score = 35.1 bits (79), Expect = 2.3, Method: Composition-based stats.
Identities = 24/148 (16%), Positives = 54/148 (36%), Gaps = 19/148 (13%)
Query 61 GTHYGKVYLLDVQGNIT-QKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEE- 118
G+ + + +V G + ++ +++ G +DG ++ L +GE+
Sbjct 170 GSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDLSTGEQL 229
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQF---VTGGKKLLLFERSWMNRWKSAVLHEGEGNIR 175
F + PI IA P+ +F V + L +++ + + +G
Sbjct 230 FKINVESPINQIAFSPN-------RFWMCVATERSLSVYDLES-KAVIAELTPDGAKPSE 281
Query 176 SVKWRGHLIAWANNMGVKIFDIISKQRI 203
+ IAW+ + G ++ I
Sbjct 282 CIS-----IAWSAD-GNTLYSGHKDNLI 303
>sp|Q3UGF1|WDR19_MOUSE WD repeat-containing protein 19 OS=Mus
musculus OX=10090 GN=Wdr19 PE=1 SV=1
Length=1341
Score = 35.8 bits (81), Expect = 2.3, Method: Composition-based stats.
Identities = 32/154 (21%), Positives = 52/154 (34%), Gaps = 22/154 (14%)
Query 44 QKDAASCMTVHD--KFLALGTHYGKVYLLDVQGNITQKFDV---SPVKINQISLDESGEH 98
+D S + FLA+GT G + + + Q ++K V KI + E+
Sbjct 96 MRDQMSFLLWSKIGSFLAVGTIKGNLLIYNHQ--TSRKIPVLGKHTKKITCGCWN--SEN 151
Query 99 MGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQ----------FVTGG 148
+ + K+ G+ +T P+K F S + V G
Sbjct 152 LLALGGEDKMITVSNQEGDTIRQT---PVKSEPSDIKFSMSKTDERISSAENTISAVVGK 208
Query 149 KKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGH 182
K L LF + + + GNI W G
Sbjct 209 KMLFLFHLNEPDNPVDLEFQQAYGNIVCYSWYGD 242
>sp|P35606|COPB2_HUMAN Coatomer subunit beta' OS=Homo sapiens
OX=9606 GN=COPB2 PE=1 SV=2
Length=906
Score = 35.8 bits (81), Expect = 2.3, Method: Composition-based stats.
Identities = 35/224 (16%), Positives = 78/224 (35%), Gaps = 20/224 (9%)
Query 34 RLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
RL + D + +H + ++ + G V + + + + F+V + +
Sbjct 4 RLDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAA 63
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFH--ETFDCPIKIIAVHPHFVRSSCKQFVTGG 148
+ ++D +++VF + E H E I+ IAVHP + +T
Sbjct 64 KFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHP-----TQPFILTSS 118
Query 149 KKLLLFERSWMNRWKSAVLHEGEGN-----IRSVKWRGHLIAWANNMGVKIFDIISKQRI 203
+L+ W +W + + EG + + + K + + + +K++ + S
Sbjct 119 DDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPN 178
Query 204 TNVPRDD-----ISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCS 242
+ + I L + L+ W K C
Sbjct 179 FTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCV 222
>sp|Q58D79|RPH3L_BOVIN Rab effector Noc2 OS=Bos taurus OX=9913
GN=RPH3AL PE=2 SV=1
Length=292
Score = 35.1 bits (79), Expect = 2.3, Method: Composition-based stats.
Identities = 22/105 (21%), Positives = 36/105 (34%), Gaps = 5/105 (5%)
Query 740 RDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPIL 799
SL + LQ++ R IL + L + T + V+ + + C C +
Sbjct 44 SQSLSPAEVEAILQVIQRAERLDILEQQRVGRLVERLETMRRNVMGNGLSQCLLCGEVLG 103
Query 800 PSDAAKPFSVVVFHCRHMFHKEC--LPMPSMNSAAQFCNICSAKN 842
++ F CR +C PS C ICS +
Sbjct 104 FLGSSSVFCK---DCRKKVCTKCGIEASPSQKRPLWLCKICSEQR 145
>sp|O55029|COPB2_MOUSE Coatomer subunit beta' OS=Mus musculus
OX=10090 GN=Copb2 PE=1 SV=2
Length=905
Score = 35.8 bits (81), Expect = 2.4, Method: Composition-based stats.
Identities = 35/224 (16%), Positives = 78/224 (35%), Gaps = 20/224 (9%)
Query 34 RLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
RL + D + +H + ++ + G V + + + + F+V + +
Sbjct 4 RLDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAA 63
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFH--ETFDCPIKIIAVHPHFVRSSCKQFVTGG 148
+ ++D +++VF + E H E I+ IAVHP + +T
Sbjct 64 KFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHP-----TQPFILTSS 118
Query 149 KKLLLFERSWMNRWKSAVLHEGEGN-----IRSVKWRGHLIAWANNMGVKIFDIISKQRI 203
+L+ W +W + + EG + + + K + + + +K++ + S
Sbjct 119 DDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPN 178
Query 204 TNVPRDD-----ISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCS 242
+ + I L + L+ W K C
Sbjct 179 FTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCV 222
>sp|B4HRQ6|CIAO1_DROSE Probable cytosolic iron-sulfur protein
assembly protein Ciao1 OS=Drosophila sechellia OX=7238 GN=Ciao1
PE=3 SV=1
Length=335
Score = 35.1 bits (79), Expect = 2.4, Method: Composition-based stats.
Identities = 24/134 (18%), Positives = 42/134 (31%), Gaps = 28/134 (21%)
Query 70 LDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKI 129
+D + T + I D GE + CS+D ++++ Y
Sbjct 180 IDNDWDCTATLTSHTSTVWGIDFDADGERLVSCSDDTTIKIWRAYHPGNTA--------G 231
Query 130 IAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLIAWA-N 188
+A C V+G +++ SW LIA A
Sbjct 232 VATPEQQTVWKCVCTVSGQHSRAIYDVSW-------------------CKLTGLIATACG 272
Query 189 NMGVKIFDIISKQR 202
+ G++IF S +
Sbjct 273 DDGIRIFKETSDSK 286
>sp|Q8NG27|PJA1_HUMAN E3 ubiquitin-protein ligase Praja-1 OS=Homo
sapiens OX=9606 GN=PJA1 PE=1 SV=2
Length=643
Score = 35.5 bits (80), Expect = 2.4, Method: Composition-based stats.
Identities = 35/150 (23%), Positives = 55/150 (37%), Gaps = 13/150 (9%)
Query 690 QDDGELWEDLILYSIDKPPFITGL-LNNIGTHVDPILLIHRIKEGMEIPNLRDSLVKILQ 748
+DD + EDL + F GL + ++VDP L + E L ++ L
Sbjct 498 EDDSSVSEDLEVDWSLFDGFADGLGVAEAISYVDPQFLTYMALE----ERLAQAMETALA 553
Query 749 DYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPFS 808
+ E +S+ L ++ T+ G V +E C C S+ K
Sbjct 554 HLESLAVDVEVANPPASKESIDALPEILVTEDHG-AVGQEMCCPIC-----CSEYVKGEV 607
Query 809 VVVFHCRHMFHKECLPMPSMNSAAQFCNIC 838
C H FHK C+ + S C +C
Sbjct 608 ATELPCHHYFHKPCVSIWLQKSGT--CPVC 635
>sp|Q4PHV3|IPI3_MYCMD Pre-rRNA-processing protein IPI3 OS=Mycosarcoma
maydis OX=5270 GN=IPI3 PE=3 SV=1
Length=587
Score = 35.5 bits (80), Expect = 2.5, Method: Composition-based stats.
Identities = 17/89 (19%), Positives = 36/89 (40%), Gaps = 4/89 (4%)
Query 30 LKYERLSNGVTEILQKDAASCMTVHDK--FLALGTHYGKVYLLDV-QGNITQKFDVSPVK 86
++R + + I+ SC+ +A G+ G++ L + G++ FD
Sbjct 89 FSWQR-DHLLQRIILPSKLSCIACSPNGDLVAGGSFDGRILLWQIATGDLLASFDAHYRS 147
Query 87 INQISLDESGEHMGVCSEDGKVQVFGLYS 115
+ + G + SED ++ V+ L
Sbjct 148 VTVLKWTCDGAGLLTGSEDARILVWSLAG 176
>sp|B4KTK4|CIAO1_DROMO Probable cytosolic iron-sulfur protein
assembly protein Ciao1 OS=Drosophila mojavensis OX=7230 GN=Ciao1
PE=3 SV=1
Length=331
Score = 35.1 bits (79), Expect = 2.6, Method: Composition-based stats.
Identities = 11/60 (18%), Positives = 22/60 (37%), Gaps = 9/60 (15%)
Query 70 LDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQV---------FGLYSGEEFH 120
LD + T + I D GE + CS+D +++ G+ + ++
Sbjct 176 LDSDWDCTATLSSHTSTVWSIDFDADGERLVSCSDDATLKIWRAYHPGNEAGIATPDKTT 235
>sp|P78750|UTP18_SCHPO Probable U3 small nucleolar RNA-associated
protein 18 OS=Schizosaccharomyces pombe (strain 972 / ATCC
24843) OX=284812 GN=SPBC29A3.06 PE=2 SV=3
Length=519
Score = 35.5 bits (80), Expect = 2.6, Method: Composition-based stats.
Identities = 25/120 (21%), Positives = 46/120 (38%), Gaps = 10/120 (8%)
Query 50 CMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQ 109
C+ +K+LA+G+ G V + D+Q T D +P + + + S+D +V
Sbjct 399 CLDPSNKYLAIGSKSGIVNIYDLQ---TSNADAAPKPVTTLDNITFSINSMSFSQDSQVL 455
Query 110 VFGLYSGEEFHETFDCPIKII------AVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWK 163
++ P + + P R +C F GG+ + E + WK
Sbjct 456 AIASRGKKDTLRLVHVPSFSVFRNWPTSATP-LGRVTCLAFGKGGELCVGNEAGRVGLWK 514
>sp|A2QHM1|SEC13_ASPNC Protein transport protein sec13 OS=Aspergillus
niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
OX=425011 GN=sec13 PE=3 SV=1
Length=308
Score = 35.1 bits (79), Expect = 2.6, Method: Composition-based stats.
Identities = 58/259 (22%), Positives = 88/259 (34%), Gaps = 54/259 (21%)
Query 33 ERLSNGVTEILQKDAASCMT-VHDKF---LALGTHYGKVYLL-DVQGNITQ--------- 78
RL + + A C+ H KF LA ++ GKV + + N T
Sbjct 46 HRLIETLKG--HEGAVWCVAWAHPKFGTILASSSYDGKVLIWREQHQNATSPVAGGAWTK 103
Query 79 --KFDVSPVKINQISL--DESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCP---IKIIA 131
F + +N +S ESG + S DG V V H+ F + I+
Sbjct 104 VFDFSLHTASVNMVSWAPHESGCLLACASSDGHVSVLEFRDNSWTHQIFHAHGMGVNSIS 163
Query 132 VHPHFVRSS----------CKQFVTGGKKLLLF------ERSWMNRWKSAVLHEGEGNIR 175
P S ++FVTGG LL E N ++ H +R
Sbjct 164 WAPAAAPGSLISSNPGPGQQRRFVTGGSDNLLKIWDYNPETKTYNNTQTLEGHSD--WVR 221
Query 176 SVKW-----RGHLIAWAN-NMGVKIF--DIISKQRITNVPRDDISLRPDMYPCSLCWKDN 227
V W IA A+ + V+I+ D + + T+ L D + W +
Sbjct 222 DVAWSPSVLSKSYIASASQDKTVRIWTSDASNPGQWTS-----QQLEFDTVLWRVSWSPS 276
Query 228 VTLIIGWGTSVKVCSVKER 246
++ G KV KE
Sbjct 277 GNILAVSGGDNKVSLWKEN 295
>sp|A1DP19|LIS1_NEOFI Nuclear distribution protein nudF OS=Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65
/ FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=nudF
PE=3 SV=1
Length=441
Score = 35.5 bits (80), Expect = 2.6, Method: Composition-based stats.
Identities = 10/55 (18%), Positives = 24/55 (44%), Gaps = 0/55 (0%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKV 108
+F A G+ + L D +GN+ + + ++ G+H+ ++D +
Sbjct 300 SAEFFATGSRDKTIRLWDSRGNLIKTLVGHDNWVRALAFHPGGKHLLSVADDKTI 354
>sp|Q9SUS4|RHA1A_ARATH Probable E3 ubiquitin-protein ligase RHA1A
OS=Arabidopsis thaliana OX=3702 GN=RHA1A PE=2 SV=1
Length=159
Score = 33.9 bits (76), Expect = 2.6, Method: Composition-based stats.
Identities = 25/140 (18%), Positives = 43/140 (31%), Gaps = 22/140 (16%)
Query 707 PPFITGLLNNIGTHVDPILLIHRIKEGME-------IPNLRDSLVKILQDYNLQILLREG 759
P L + + +I ++ ++ +P D D L
Sbjct 4 PEDFITELQIPSYILKILYVIGFFRDIVDALCPYIGLPRFLDHNETSAPDLTRHAL---- 59
Query 760 CKKILVADSLSLLKKMHRTQMKG-VLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMF 818
+ S SL ++ + D E+ C CLS D + C H+F
Sbjct 60 ------STSASLANELIPVVRFSDLPTDPEDCCTVCLSDFESDDKVRQLP----KCGHVF 109
Query 819 HKECLPMPSMNSAAQFCNIC 838
H CL ++ C +C
Sbjct 110 HHYCLDRWIVDYNKMKCPVC 129
>sp|Q4WLM7|LIS1_ASPFU Nuclear distribution protein nudF OS=Aspergillus
fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC
A1100 / Af293) OX=330879 GN=nudF PE=3 SV=1
Length=467
Score = 35.5 bits (80), Expect = 2.7, Method: Composition-based stats.
Identities = 10/55 (18%), Positives = 24/55 (44%), Gaps = 0/55 (0%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKV 108
+F A G+ + L D +GN+ + + ++ G+H+ ++D +
Sbjct 326 SAEFFATGSRDKTIRLWDSRGNLIKTLVGHDNWVRALAFHPGGKHLLSVADDKTI 380
>sp|B0XM00|LIS1_ASPFC Nuclear distribution protein nudF OS=Aspergillus
fumigatus (strain CBS 144.89 / FGSC A1163 / CEA10)
OX=451804 GN=nudF PE=3 SV=1
Length=467
Score = 35.5 bits (80), Expect = 2.7, Method: Composition-based stats.
Identities = 10/55 (18%), Positives = 24/55 (44%), Gaps = 0/55 (0%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKV 108
+F A G+ + L D +GN+ + + ++ G+H+ ++D +
Sbjct 326 SAEFFATGSRDKTIRLWDSRGNLIKTLVGHDNWVRALAFHPGGKHLLSVADDKTI 380
>sp|Q8R1Z9|RN121_MOUSE E3 ubiquitin ligase Rnf121 OS=Mus musculus
OX=10090 GN=Rnf121 PE=1 SV=1
Length=327
Score = 35.1 bits (79), Expect = 2.7, Method: Composition-based stats.
Identities = 14/78 (18%), Positives = 26/78 (33%), Gaps = 2/78 (3%)
Query 766 ADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPF--SVVVFHCRHMFHKECL 823
AD ++ + +++C C I + + C H+FH+ C+
Sbjct 201 ADYMASTIGFYSESGMPTKHLSDSVCAVCGQQIFVDVNEEGIIENTYRLSCNHVFHEFCI 260
Query 824 PMPSMNSAAQFCNICSAK 841
+ Q C C K
Sbjct 261 RGWCIVGKKQTCPYCKEK 278
>sp|Q06078|UTP21_YEAST U3 small nucleolar RNA-associated protein
21 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OX=559292 GN=UTP21 PE=1 SV=1
Length=939
Score = 35.5 bits (80), Expect = 2.7, Method: Composition-based stats.
Identities = 32/171 (19%), Positives = 60/171 (35%), Gaps = 16/171 (9%)
Query 57 FLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYS 115
F +G+ G + + ++Q G + +K+ + + ISLD M C DG + G Y
Sbjct 474 FGFIGSSNGSITIYNMQSGILRKKYKLHKRAVTGISLDGMNRKMVSCGLDG---IVGFYD 530
Query 116 GEEF----HETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVL--HE 169
+ D PI + H S F L + + + L H
Sbjct 531 FNKSTLLGKLKLDAPITAMVYH-----RSSDLFALALDDLSIVVIDAVTQRVVRQLWGHS 585
Query 170 GEGNIRSVKWRGHLIAWAN-NMGVKIFDIISKQRITNVPRDDISLRPDMYP 219
G I A+ + ++ +D+ + I + D+++ P
Sbjct 586 NRITAFDFSPEGRWIVSASLDSTIRTWDLPTGGCIDGIIVDNVATNVKFSP 636
>sp|Q13702|RAPSN_HUMAN 43 kDa receptor-associated protein of the
synapse OS=Homo sapiens OX=9606 GN=RAPSN PE=1 SV=4
Length=412
Score = 35.1 bits (79), Expect = 2.8, Method: Composition-based stats.
Identities = 17/64 (27%), Positives = 24/64 (38%), Gaps = 9/64 (14%)
Query 784 LVDEENI-CESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKN 842
V+E + C C I K + C H+FH CL N+ + C C +
Sbjct 355 CVEETELYCGLCGESI----GEKNSRLQALPCSHIFHLRCLQ----NNGTRSCPNCRRSS 406
Query 843 RGPG 846
PG
Sbjct 407 MKPG 410
>sp|Q5AEF2|SEC13_CANAL Protein transport protein SEC13 OS=Candida
albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=SEC13
PE=1 SV=2
Length=298
Score = 35.1 bits (79), Expect = 2.9, Method: Composition-based stats.
Identities = 28/140 (20%), Positives = 53/140 (38%), Gaps = 13/140 (9%)
Query 82 VSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH-----ETFDCPIKIIAV-HPH 135
I+ LD G+ + CS D +++F L + + + P+ ++ HP
Sbjct 7 AHDDLIHDAVLDYYGKRLATCSSDKTIKIFDLDGTDNYKLITTLTGHEGPVWQVSWAHPK 66
Query 136 FVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEG-EGNIRSVKWRGH-----LIAWANN 189
F G K L+ E+ +W H + ++ SV W H L+ +++
Sbjct 67 FGSILASCSYDG-KALIWKEQPETQQWSIIAEHTVHQASVNSVSWAPHELGAVLLCTSSD 125
Query 190 MGVKIFDIISKQRITNVPRD 209
V + D ++V D
Sbjct 126 GKVSVVDFNDDGTTSHVIFD 145
>sp|P36130|CAF4_YEAST CCR4-associated factor 4 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=CAF4
PE=1 SV=3
Length=643
Score = 35.5 bits (80), Expect = 2.9, Method: Composition-based stats.
Identities = 13/72 (18%), Positives = 30/72 (42%), Gaps = 2/72 (3%)
Query 46 DAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSED 105
D + + + L G+ V + D++ + + ++ + D G+ + V + +
Sbjct 530 DGITSLKFDSEKLVTGSMDNSVRIWDLRTSSILDVIAYDLPVSSLDFD--GKLITVGANE 587
Query 106 GKVQVFGLYSGE 117
G V VF + E
Sbjct 588 GGVNVFNMERDE 599
>sp|Q16MY0|WDR48_AEDAE WD repeat-containing protein 48 homolog
OS=Aedes aegypti OX=7159 GN=AAEL012158 PE=3 SV=1
Length=659
Score = 35.5 bits (80), Expect = 3.0, Method: Composition-based stats.
Identities = 24/173 (14%), Positives = 63/173 (36%), Gaps = 19/173 (11%)
Query 44 QKDAASCMTV--HDKFLALGTHYGKVYLLDVQG-NITQKFDVSPVKINQISLDESGEHMG 100
KD+ + + + G+ + + D + N K + + + E G+H+
Sbjct 167 SKDSIYSLAMNPSGTVIVCGSTENTLRIWDPRTCNKIAKLKGHAENVKALVVSEDGQHVI 226
Query 101 VCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPH-----FVRSSCKQFVTGGKKLLLFE 155
S DGK++ + + ++ I+VH + + ++G + +
Sbjct 227 SGSSDGKIKQWSIGQ--------QRCVQTISVHSEGVWALLMTDNFSHVISGSRDKKIIM 278
Query 156 RSWMNRWKSAVLHEGEGNIRSVKWRGHLI-AWAN--NMGVKIFDIISKQRITN 205
N S ++ E + S+ + WA N ++ + + ++++
Sbjct 279 TDLRNPTNSVLICEERAPVLSLCYNYDQTGVWATTWNSDIRCWKLNPSEKLSF 331
>sp|Q28I85|POC1A_XENTR POC1 centriolar protein homolog A OS=Xenopus
tropicalis OX=8364 GN=poc1a PE=2 SV=1
Length=441
Score = 35.1 bits (79), Expect = 3.0, Method: Composition-based stats.
Identities = 19/96 (20%), Positives = 36/96 (38%), Gaps = 8/96 (8%)
Query 58 LALGTHYGKVYLLDVQGN-ITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSG 116
+A V + D++ N + Q + V +N +S SG ++ S D ++V L G
Sbjct 201 IAAAATDNTVKVWDIRMNKLIQHYQVHSGVVNSLSFHPSGNYLITASNDSTLKVLDLLEG 260
Query 117 EEFH--ETFDCPIKIIAVHPHFVRSSCKQFVTGGKK 150
+ P+ + + F +GG
Sbjct 261 RLLYTLHGHQGPVTSVKFS-----REGEFFASGGSD 291
>sp|A5E6M3|RTC1_LODEL Restriction of telomere capping protein
1 OS=Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605
/ JCM 1781 / NBRC 1676 / NRRL YB-4239) OX=379508 GN=RTC1 PE=3
SV=1
Length=1163
Score = 35.5 bits (80), Expect = 3.1, Method: Composition-based stats.
Identities = 31/208 (15%), Positives = 70/208 (34%), Gaps = 39/208 (19%)
Query 47 AASCMTVHDKFLALGTHYGKVYLLDV----QGNITQKFDVSPVKINQISLDESGEHMGVC 102
+ + + + +A G G + + V +G + +N I +S +H+
Sbjct 136 SVNTIKTRENTIACGMSNGTISMYKVSPYGKGTLHAMLSDHRRTVNSIDFIDSTDHIISG 195
Query 103 SEDGKVQVFGL-YSGEEFHETF-----DCPIKIIAVHPHFVRSSCKQFVT---------- 146
S+DG ++++ L S + + PI+ PH V + ++
Sbjct 196 SQDGSIKLWDLRASPTKPVFNLQANLHNDPIRACQYSPHSVVRNKTCILSVHDSGALCKF 255
Query 147 -----GGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWR--GHLIAWAN-NMGVKIFDII 198
G + +R W LH G + S+ +A + + +F+
Sbjct 256 DLRSGSGSNMYSPDRKW-------NLHA--GPVLSLHIHPEKEYVATGGRDHKICVFNYS 306
Query 199 SKQRITNVPRDDISLRPDMYPCSLCWKD 226
+ + P + I+ + + W
Sbjct 307 EGRSLRTTPENIINTYGSIL--KVRWSS 332
>sp|Q6P360|RN121_XENTR E3 ubiquitin ligase Rnf121 OS=Xenopus tropicalis
OX=8364 GN=rnf121 PE=2 SV=1
Length=327
Score = 35.1 bits (79), Expect = 3.1, Method: Composition-based stats.
Identities = 14/78 (18%), Positives = 26/78 (33%), Gaps = 2/78 (3%)
Query 766 ADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPF--SVVVFHCRHMFHKECL 823
AD ++ + +++C C I + + C H+FH+ C+
Sbjct 201 ADYMASTIGFYSASGMPTKHLSDSVCAVCGQQIFVDVNEEGIIENTYRLSCNHVFHEFCI 260
Query 824 PMPSMNSAAQFCNICSAK 841
+ Q C C K
Sbjct 261 RGWCIVGKKQTCPYCKEK 278
>sp|Q6DD32|RN121_XENLA E3 ubiquitin ligase Rnf121 OS=Xenopus laevis
OX=8355 GN=rnf121 PE=2 SV=1
Length=327
Score = 35.1 bits (79), Expect = 3.1, Method: Composition-based stats.
Identities = 14/78 (18%), Positives = 26/78 (33%), Gaps = 2/78 (3%)
Query 766 ADSLSLLKKMHRTQMKGVLVDEENICESCLSPILPSDAAKPF--SVVVFHCRHMFHKECL 823
AD ++ + +++C C I + + C H+FH+ C+
Sbjct 201 ADYMASTIGFYSASGMPTKHLSDSVCAVCGQQIFVDVNEEGIIENTYRLSCNHVFHEFCI 260
Query 824 PMPSMNSAAQFCNICSAK 841
+ Q C C K
Sbjct 261 RGWCIVGKKQTCPYCKEK 278
>sp|A6ZZZ8|CAF4_YEAS7 CCR4-associated factor 4 OS=Saccharomyces
cerevisiae (strain YJM789) OX=307796 GN=CAF4 PE=3 SV=2
Length=645
Score = 35.1 bits (79), Expect = 3.1, Method: Composition-based stats.
Identities = 13/72 (18%), Positives = 30/72 (42%), Gaps = 2/72 (3%)
Query 46 DAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSED 105
D + + + L G+ V + D++ + + ++ + D G+ + V + +
Sbjct 532 DGITSLKFDSEKLVTGSMDNSVRIWDLRTSSILDVIAYDLPVSSLDFD--GKLITVGANE 589
Query 106 GKVQVFGLYSGE 117
G V VF + E
Sbjct 590 GGVNVFNMERDE 601
>sp|Q5REG7|LIS1_PONAB Platelet-activating factor acetylhydrolase
IB subunit alpha OS=Pongo abelii OX=9601 GN=PAFAH1B1 PE=2
SV=3
Length=410
Score = 35.1 bits (79), Expect = 3.1, Method: Composition-based stats.
Identities = 25/162 (15%), Positives = 58/162 (36%), Gaps = 25/162 (15%)
Query 62 THYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE--E 118
+ + + D + G+ + I I D SG+ + CS D ++++ E
Sbjct 127 SEDATIKVWDYETGDFERTLKGHTDSIQDIPFDHSGKLLASCSADMTIKLWDFQGFECIR 186
Query 119 FHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFER-SWMNRWKSAVLHEGEGNIRSV 177
D + +A+ P+ G ++ R + W+ + +
Sbjct 187 TMHGHDHNVSSVAIMPN------------GDHIVSASRDKTIKMWEVQTGYCVKTFTGHR 234
Query 178 KW--------RGHLIA-WANNMGVKIFDIISKQRITNVPRDD 210
+W G LIA +N+ V+++ + +K+ + +
Sbjct 235 EWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHE 276
>sp|Q9LT47|FIE_ARATH Polycomb group protein FERTILIZATION-INDEPENDENT
ENDOSPERM OS=Arabidopsis thaliana OX=3702 GN=FIE PE=1
SV=2
Length=369
Score = 35.1 bits (79), Expect = 3.1, Method: Composition-based stats.
Identities = 23/96 (24%), Positives = 40/96 (42%), Gaps = 14/96 (15%)
Query 27 EPKLKYERLSNGVTEILQKDAAS---------CMTVHDKFLALGTHYGKVYLLDVQG--- 74
EP+LK G +++L + +H +A+G GKVY+ D++
Sbjct 266 EPQLKENSPGEGASDVLLRYPVPMCDIWFIKFSCDLHLSSVAIGNQEGKVYVWDLKSCPP 325
Query 75 NITQKFDVSPVK--INQISLDESGEHMGVCSEDGKV 108
+ K + K I Q ++ G + C EDG +
Sbjct 326 VLITKLSHNQSKSVIRQTAMSVDGSTILACCEDGTI 361
>sp|Q01277|SCONB_NEUCR Probable E3 ubiquitin ligase complex SCF
subunit scon-2 OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A
/ CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=scon-2
PE=1 SV=1
Length=650
Score = 35.1 bits (79), Expect = 3.2, Method: Composition-based stats.
Identities = 12/72 (17%), Positives = 26/72 (36%), Gaps = 0/72 (0%)
Query 46 DAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSED 105
D+ + LA G+ V + D T +N +D + S+D
Sbjct 375 DSVISVHFDGHLLASGSSDKTVKIFDFNSKETYCLKGHSDWVNSTHVDIKSRTVFSASDD 434
Query 106 GKVQVFGLYSGE 117
++++ L + +
Sbjct 435 TTIKLWDLDTRQ 446
>sp|Q96L73|NSD1_HUMAN Histone-lysine N-methyltransferase, H3 lysine-36
specific OS=Homo sapiens OX=9606 GN=NSD1 PE=1 SV=1
Length=2696
Score = 35.5 bits (80), Expect = 3.2, Method: Composition-based stats.
Identities = 21/94 (22%), Positives = 35/94 (37%), Gaps = 11/94 (12%)
Query 747 LQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSP--ILPSDAA 804
L + +E ++ + D K + + G +EN+C++C +L +A
Sbjct 1502 LMPHRTATSPKETVEEGVEHDPGMPASKKMQGERGGGAALKENVCQNCEKLGELLLCEA- 1560
Query 805 KPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNIC 838
C FH ECL + M CN C
Sbjct 1561 --------QCCGAFHLECLGLTEMPRGKFICNEC 1586
>sp|F4IDY5|BTSL1_ARATH Zinc finger protein BRUTUS-like At1g18910
OS=Arabidopsis thaliana OX=3702 GN=At1g18910 PE=2 SV=1
Length=1254
Score = 35.5 bits (80), Expect = 3.3, Method: Composition-based stats.
Identities = 14/52 (27%), Positives = 19/52 (37%), Gaps = 6/52 (12%)
Query 788 ENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICS 839
E+ C C I S++ V C H+ H C + C ICS
Sbjct 1145 EDNCPICHEYIFTSNSP----VKALPCGHVMHSTCFQ--EYTCSHYTCPICS 1190
>sp|Q8W1K8|MUT11_CHLRE Protein Mut11 OS=Chlamydomonas reinhardtii
OX=3055 GN=Mut11 PE=2 SV=1
Length=370
Score = 34.7 bits (78), Expect = 3.5, Method: Composition-based stats.
Identities = 18/93 (19%), Positives = 33/93 (35%), Gaps = 7/93 (8%)
Query 50 CMTV---HDKFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSED 105
C LA G+ + L DV+ G ++ + + G + S D
Sbjct 129 CCNFDGAAGHLLASGSFDETLRLWDVRSGRCLREVPAHSDPVTSAAFSYDGSMVVTSSLD 188
Query 106 GKVQVFGLYSGEEFHETFDC---PIKIIAVHPH 135
G ++++ +G FD P+ A P+
Sbjct 189 GLIRLWDTQTGHCLKTLFDRDSPPVSFAAFTPN 221
>sp|F4IH25|BOP1_ARATH Ribosome biogenesis protein BOP1 homolog
OS=Arabidopsis thaliana OX=3702 GN=BOP1 PE=1 SV=1
Length=753
Score = 35.1 bits (79), Expect = 3.6, Method: Composition-based stats.
Identities = 16/59 (27%), Positives = 27/59 (46%), Gaps = 1/59 (2%)
Query 77 TQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHE-TFDCPIKIIAVHP 134
++ + IS D SGE + S DG V+++ + +G FD I +A +P
Sbjct 416 YLEYKGHTGAVTSISTDSSGEWIASGSTDGSVRMWEVETGRCLKVWQFDEAIMCVAWNP 474
>sp|P12672|RAPSN_MOUSE 43 kDa receptor-associated protein of the
synapse OS=Mus musculus OX=10090 GN=Rapsn PE=2 SV=4
Length=412
Score = 34.7 bits (78), Expect = 3.6, Method: Composition-based stats.
Identities = 16/64 (25%), Positives = 24/64 (38%), Gaps = 9/64 (14%)
Query 784 LVDEENI-CESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKN 842
V+E + C C I + + C H+FH CL N+ + C C +
Sbjct 355 CVEETELYCGLCGESI----GERNSRLQALPCSHIFHLRCLQ----NNGTRSCPNCRRSS 406
Query 843 RGPG 846
PG
Sbjct 407 MKPG 410
>sp|A5DXE2|SEC13_LODEL Protein transport protein SEC13 OS=Lodderomyces
elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781
/ NBRC 1676 / NRRL YB-4239) OX=379508 GN=SEC13 PE=3 SV=1
Length=304
Score = 34.7 bits (78), Expect = 3.7, Method: Composition-based stats.
Identities = 30/140 (21%), Positives = 54/140 (39%), Gaps = 13/140 (9%)
Query 82 VSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHET-----FDCPIKIIAV-HPH 135
I+ LD G+ + CS D ++++ + E + T + PI +A HP
Sbjct 7 AHEDLIHDAVLDYYGKRLATCSSDKTIKIYDIEGTENYKLTATLTGHEGPIWQVAWAHPK 66
Query 136 FVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEG-EGNIRSVKWRGH-----LIAWANN 189
F G K L+ E+ +W H + ++ SV W H L+ +++
Sbjct 67 FGSILASCSYDG-KVLIWKEQQDTQQWSIIAEHTIHQASVNSVSWAPHELGAVLLCTSSD 125
Query 190 MGVKIFDIISKQRITNVPRD 209
V + D ++V D
Sbjct 126 GKVSVVDFNDDGTTSHVIFD 145
>sp|Q2KIG2|WDR5_BOVIN WD repeat-containing protein 5 OS=Bos taurus
OX=9913 GN=WDR5 PE=2 SV=1
Length=334
Score = 34.7 bits (78), Expect = 3.9, Method: Composition-based stats.
Identities = 14/92 (15%), Positives = 35/92 (38%), Gaps = 6/92 (7%)
Query 50 CMTVHDK--FLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDG 106
C + + + G+ V + DV+ G + ++ + + G + S DG
Sbjct 134 CCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Query 107 KVQVFGLYSGE---EFHETFDCPIKIIAVHPH 135
+++ SG+ + + P+ + P+
Sbjct 194 LCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 225
>sp|Q5BLX8|WDR83_RAT WD repeat domain-containing protein 83 OS=Rattus
norvegicus OX=10116 GN=Wdr83 PE=1 SV=1
Length=315
Score = 34.7 bits (78), Expect = 4.0, Method: Composition-based stats.
Identities = 18/64 (28%), Positives = 25/64 (39%), Gaps = 3/64 (5%)
Query 46 DAASCMTVHDKFLALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSE 104
DAA + L G V L DV G + +KF K+N + +E + S
Sbjct 72 DAAGSFD--NSHLCSGGGDKTVVLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILSGSI 129
Query 105 DGKV 108
D V
Sbjct 130 DSSV 133
>sp|Q9DAJ4|WDR83_MOUSE WD repeat domain-containing protein 83
OS=Mus musculus OX=10090 GN=Wdr83 PE=1 SV=1
Length=315
Score = 34.7 bits (78), Expect = 4.0, Method: Composition-based stats.
Identities = 18/64 (28%), Positives = 25/64 (39%), Gaps = 3/64 (5%)
Query 46 DAASCMTVHDKFLALGTHYGKVYLLDV-QGNITQKFDVSPVKINQISLDESGEHMGVCSE 104
DAA + L G V L DV G + +KF K+N + +E + S
Sbjct 72 DAAGSFD--NSHLCSGGGDKTVVLWDVATGQVVRKFRGHAGKVNTVQFNEEATVILSGSI 129
Query 105 DGKV 108
D V
Sbjct 130 DSSV 133
>sp|Q9LYK6|APRF1_ARATH Protein ANTHESIS POMOTING FACTOR 1 OS=Arabidopsis
thaliana OX=3702 GN=APRF1 PE=2 SV=1
Length=330
Score = 34.7 bits (78), Expect = 4.0, Method: Composition-based stats.
Identities = 25/127 (20%), Positives = 43/127 (34%), Gaps = 6/127 (5%)
Query 58 LALGTHYGKVYLLDVQGNITQKFDV-----SPVKINQISLDESGEHMGVCSEDGKVQVFG 112
A+ G V L D + FD ++N I G+ M + + + + V
Sbjct 169 FAIAMEGGAVKLFDSRCYDKGPFDTFLVGGDTAEVNDIKFSNDGKSMLLTTTNNNIYVLD 228
Query 113 LYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEG 172
Y GE+ P + + F K ++G L + N + A G
Sbjct 229 AYRGEKKCGFSLEPSQGTPIEATFTP-DGKYVLSGSGDGTLHAWNIENPSEVARWENNIG 287
Query 173 NIRSVKW 179
+ +KW
Sbjct 288 VVSCLKW 294
>sp|B8M0Q1|LIS1_TALSN Nuclear distribution protein nudF OS=Talaromyces
stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759
/ NRRL 1006) OX=441959 GN=nudF PE=3 SV=1
Length=459
Score = 34.7 bits (78), Expect = 4.1, Method: Composition-based stats.
Identities = 23/129 (18%), Positives = 49/129 (38%), Gaps = 7/129 (5%)
Query 26 EEPKLKYERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPV 85
P+ Y+ L+ ++K+A S + +F+A G+ + + D +G+
Sbjct 298 VAPQTSYQYLA--PMAGVKKEAVSKLG-AVEFIATGSRDKTIKVWDRRGSCLMTLVGHDN 354
Query 86 KINQISLDESGEHMGVCSEDGKVQVFGLYSG----EEFHETFDCPIKIIAVHPHFVRSSC 141
I I G+++ S+D ++ + L + E I + P+ V+
Sbjct 355 WIRAIVFHPGGKYLLSSSDDRSIRCWDLSQDGKCVKTLSEAHGHFISSLRWAPNVVKEVA 414
Query 142 KQFVTGGKK 150
+G K
Sbjct 415 NNADSGNGK 423
>sp|Q96KV7|WDR90_HUMAN WD repeat-containing protein 90 OS=Homo
sapiens OX=9606 GN=WDR90 PE=1 SV=2
Length=1748
Score = 35.1 bits (79), Expect = 4.1, Method: Composition-based stats.
Identities = 18/59 (31%), Positives = 29/59 (49%), Gaps = 1/59 (2%)
Query 60 LGTHYGKVYLLD-VQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE 117
+GT G ++ + +G T+ K+N++ H CSEDG V+V+ L S E
Sbjct 1410 VGTTAGTLWFVSWAEGTSTRLISGHRSKVNEVVFSPGESHCATCSEDGSVRVWALASME 1468
>sp|Q9GL21|UACA_CANLF Uveal autoantigen with coiled-coil domains
and ankyrin repeats OS=Canis lupus familiaris OX=9615 GN=UACA
PE=2 SV=2
Length=1415
Score = 35.1 bits (79), Expect = 4.1, Method: Composition-based stats.
Identities = 25/155 (16%), Positives = 66/155 (43%), Gaps = 7/155 (5%)
Query 637 HCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKAIEFAKEQDDGELW 696
H E+A + Q+ + +++ ++ L + + +++E HD+++A+ E+ + +L
Sbjct 1016 HVREEEAKKYKQENDKLKKEIFTLQKDLKDK---NVLIENSHDMERALNRKAEELNKQLK 1072
Query 697 EDLILYSIDKPPFITGLLNNIGTHVDPI----LLIHRIKEGMEIPNLRDSLVKILQDYNL 752
+ L YS K + +N + + LL + ++ L+ SL ++
Sbjct 1073 DLLQKYSEIKTEKEKLVDDNARQTSELLAAQTLLQKQHVPLEQVETLKKSLNSTIEHLKE 1132
Query 753 QILLREGCKKILVADSLSLLKKMHRTQMKGVLVDE 787
++ ++ C + L + + + V + E
Sbjct 1133 ELKNKQKCYEKEQQTVAKLHQMLENQKNSSVPLGE 1167
>sp|Q498M4|WDR5_RAT WD repeat-containing protein 5 OS=Rattus norvegicus
OX=10116 GN=Wdr5 PE=1 SV=1
Length=334
Score = 34.3 bits (77), Expect = 4.1, Method: Composition-based stats.
Identities = 14/92 (15%), Positives = 35/92 (38%), Gaps = 6/92 (7%)
Query 50 CMTVHDK--FLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDG 106
C + + + G+ V + DV+ G + ++ + + G + S DG
Sbjct 134 CCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Query 107 KVQVFGLYSGE---EFHETFDCPIKIIAVHPH 135
+++ SG+ + + P+ + P+
Sbjct 194 LCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 225
>sp|P61965|WDR5_MOUSE WD repeat-containing protein 5 OS=Mus musculus
OX=10090 GN=Wdr5 PE=1 SV=1
Length=334
Score = 34.3 bits (77), Expect = 4.1, Method: Composition-based stats.
Identities = 14/92 (15%), Positives = 35/92 (38%), Gaps = 6/92 (7%)
Query 50 CMTVHDK--FLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDG 106
C + + + G+ V + DV+ G + ++ + + G + S DG
Sbjct 134 CCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Query 107 KVQVFGLYSGE---EFHETFDCPIKIIAVHPH 135
+++ SG+ + + P+ + P+
Sbjct 194 LCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 225
>sp|P61964|WDR5_HUMAN WD repeat-containing protein 5 OS=Homo sapiens
OX=9606 GN=WDR5 PE=1 SV=1
Length=334
Score = 34.3 bits (77), Expect = 4.1, Method: Composition-based stats.
Identities = 14/92 (15%), Positives = 35/92 (38%), Gaps = 6/92 (7%)
Query 50 CMTVHDK--FLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDG 106
C + + + G+ V + DV+ G + ++ + + G + S DG
Sbjct 134 CCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Query 107 KVQVFGLYSGE---EFHETFDCPIKIIAVHPH 135
+++ SG+ + + P+ + P+
Sbjct 194 LCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 225
>sp|Q9V3J8|WDS_DROME Protein will die slowly OS=Drosophila melanogaster
OX=7227 GN=wds PE=1 SV=1
Length=361
Score = 34.7 bits (78), Expect = 4.2, Method: Composition-based stats.
Identities = 14/92 (15%), Positives = 35/92 (38%), Gaps = 6/92 (7%)
Query 50 CMTVHDK--FLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDG 106
C + + + G+ V + DV+ G + ++ + + G + S DG
Sbjct 161 CCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG 220
Query 107 KVQVFGLYSGE---EFHETFDCPIKIIAVHPH 135
+++ SG+ + + P+ + P+
Sbjct 221 LCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 252
>sp|B8PD53|LIS12_POSPM Nuclear distribution protein PAC1-2 OS=Postia
placenta (strain ATCC 44394 / Madison 698-R) OX=561896
GN=PAC1-2 PE=3 SV=1
Length=427
Score = 34.7 bits (78), Expect = 4.2, Method: Composition-based stats.
Identities = 13/66 (20%), Positives = 26/66 (39%), Gaps = 3/66 (5%)
Query 48 ASCMTVHDKF--LALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSE 104
+ + H F LA + V + D + G+ + ++ + D G + CS
Sbjct 111 ITRVAFHPTFSLLASASEDTTVKIWDWETGSFERTLKGHTREVWGVDFDSKGSFLATCSS 170
Query 105 DGKVQV 110
D ++V
Sbjct 171 DLSIKV 176
>sp|Q6H8D6|COB23_ORYSJ Putative coatomer subunit beta'-3 OS=Oryza
sativa subsp. japonica OX=39947 GN=Os02g0209000 PE=3 SV=2
Length=910
Score = 34.7 bits (78), Expect = 4.3, Method: Composition-based stats.
Identities = 25/133 (19%), Positives = 56/133 (42%), Gaps = 10/133 (8%)
Query 34 RLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
RL + + A + +H + ++ + G V + + Q + F+V+ + +
Sbjct 4 RLDIKRKLAQRSERAKSVDLHPTEPWILSSLYSGSVCIWNYQTQTMVKSFEVTELPVRSS 63
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFH--ETFDCPIKIIAVHPH--FVRSSCKQFVT 146
+ + ++D ++V+ + ++ E I+ +AVHP FV SS +
Sbjct 64 KFITRKQWVVAGADDMFIRVYNYNTMDKVKVFEAHTDYIRCVAVHPTQPFVLSSSDDMLI 123
Query 147 GGKKLLLFERSWM 159
KL +++ WM
Sbjct 124 ---KLWDWDKGWM 133
>sp|Q6ZNJ1|NBEL2_HUMAN Neurobeachin-like protein 2 OS=Homo sapiens
OX=9606 GN=NBEAL2 PE=1 SV=2
Length=2754
Score = 35.1 bits (79), Expect = 4.4, Method: Composition-based stats.
Identities = 16/63 (25%), Positives = 32/63 (51%), Gaps = 1/63 (2%)
Query 49 SCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVS-PVKINQISLDESGEHMGVCSEDGK 107
+ +TV + F+ LGT +++L + + + V I +++ + H+ V EDGK
Sbjct 2651 TALTVTEDFVLLGTAQCALHILQLNTLLPAAPPLPMKVAIRSVAVTKERSHVLVGLEDGK 2710
Query 108 VQV 110
+ V
Sbjct 2711 LIV 2713
>sp|Q62191|RO52_MOUSE E3 ubiquitin-protein ligase TRIM21 OS=Mus
musculus OX=10090 GN=Trim21 PE=1 SV=1
Length=470
Score = 34.7 bits (78), Expect = 4.4, Method: Composition-based stats.
Identities = 16/52 (31%), Positives = 21/52 (40%), Gaps = 9/52 (17%)
Query 787 EENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNIC 838
EE C CL P+ +P S+ C H F KEC+ + C C
Sbjct 16 EEVTCSICLDPM-----VEPMSI---ECGHCFCKECI-FEVGKNGGSSCPEC 58
>sp|Q9CAA0|COB21_ARATH Coatomer subunit beta'-1 OS=Arabidopsis
thaliana OX=3702 GN=At1g79990 PE=2 SV=2
Length=920
Score = 34.7 bits (78), Expect = 4.4, Method: Composition-based stats.
Identities = 23/133 (17%), Positives = 55/133 (41%), Gaps = 10/133 (8%)
Query 34 RLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQGNI-TQKFDVSPVKINQI 90
RL + + + +H + ++ + G + + + Q + FDV+ + +
Sbjct 4 RLEIKRKFAQRSERVKSVDLHPTEPWILASLYSGTLCIWNYQTQTMVKSFDVTELPVRSA 63
Query 91 SLDESGEHMGVCSEDGKVQVFGLYSGEEFH--ETFDCPIKIIAVHPH--FVRSSCKQFVT 146
+ + ++D ++V+ + ++ E I+ +AVHP +V SS +
Sbjct 64 KFIARKQWVVAGADDMFIRVYNYNTMDKIKVFEAHADYIRCVAVHPTLPYVLSSSDDMLI 123
Query 147 GGKKLLLFERSWM 159
KL +E+ W+
Sbjct 124 ---KLWDWEKGWL 133
>sp|Q5F201|CFA52_MOUSE Cilia- and flagella-associated protein
52 OS=Mus musculus OX=10090 GN=Cfap52 PE=1 SV=1
Length=620
Score = 34.7 bits (78), Expect = 4.5, Method: Composition-based stats.
Identities = 32/181 (18%), Positives = 70/181 (39%), Gaps = 20/181 (11%)
Query 82 VSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGE---EFHETFDCPIKIIAVHPHFVR 138
V + + I G+ + +DGK++ F SG + + IA
Sbjct 372 VPNMTCHGIDFMRDGKSIISAWDDGKIRAFAPESGRLMYTINSAHRIGVTAIATTSD--- 428
Query 139 SSCKQFVTGG--KKLLLFERSWMNRWKSAVLHEGEGNIRSV---KWRGHLIAWANNMGVK 193
CK+ ++GG ++ +++ + L E + ++ + K + + +
Sbjct 429 --CKRIISGGGEGEVRVWQVGCQTQKLEEALKEHKSSVSCIRVKKNNEECVTASTDGTCI 486
Query 194 IFDIISKQRITNVPRDDISLRPDMYPCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRD 253
I+D + + R+ + L ++ C +C+ II GT K+ + S +R+
Sbjct 487 IWD------LVRLRRNQMILANTLFQC-VCYHPEEFQIITSGTDRKIAYWEVFDGSVIRE 539
Query 254 L 254
L
Sbjct 540 L 540
>sp|Q6CN23|HSV2_KLULA SVP1-like protein 2 OS=Kluyveromyces lactis
(strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL
Y-1140 / WM37) OX=284590 GN=HSV2 PE=1 SV=1
Length=339
Score = 34.3 bits (77), Expect = 4.6, Method: Composition-based stats.
Identities = 20/132 (15%), Positives = 39/132 (30%), Gaps = 22/132 (17%)
Query 82 VSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAV-----HPHF 136
+ + L+ G+ + CS+DG + F + ++ P
Sbjct 177 AHANPVKMVRLNRKGDMVATCSQDGTLIRVFQTDNGVLVREFRRGLDRTSIIDMRWSPDG 236
Query 137 VRSSCKQFVTGGKKLLLFE------------RSWMNRWKSAVLHEGEGNIRSVK--WRGH 182
+ + V+ L +FE + W+N V
Sbjct 237 SKLA---VVSDKWTLHVFEVFNDAENKRHVLKDWINIKYFQSEWSICNFKLKVSKGSNDC 293
Query 183 LIAWANNMGVKI 194
IAW ++ G+ I
Sbjct 294 KIAWISDTGLVI 305
>sp|B8D8T3|QUEA_BUCA5 S-adenosylmethionine:tRNA ribosyltransferase-isomerase
OS=Buchnera aphidicola subsp. Acyrthosiphon pisum
(strain 5A) OX=563178 GN=queA PE=3 SV=1
Length=357
Score = 34.3 bits (77), Expect = 4.6, Method: Composition-based stats.
Identities = 14/40 (35%), Positives = 25/40 (63%), Gaps = 0/40 (0%)
Query 121 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMN 160
+FD P +I+ HP+F+RS+C+ V G ++F + + N
Sbjct 6 FSFDLPKSLISFHPYFIRSTCRLMVMYGHTGMIFHKRFFN 45
>sp|A2QP30|LIS1_ASPNC Nuclear distribution protein nudF OS=Aspergillus
niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513)
OX=425011 GN=nudF PE=3 SV=1
Length=443
Score = 34.3 bits (77), Expect = 4.7, Method: Composition-based stats.
Identities = 14/66 (21%), Positives = 26/66 (39%), Gaps = 5/66 (8%)
Query 45 KDAASCMTVHDKF--LALGTHYGKVYLLD-VQGNITQKFDVSPVKINQISLDESGEH--M 99
+DA +C+ H F LA G+ + + D G + + ++ + H +
Sbjct 113 RDAVTCVAFHPVFTSLASGSEDCTIKIWDWELGELERTLKGHMRPVSDLDFGGQKGHTIL 172
Query 100 GVCSED 105
CS D
Sbjct 173 ASCSSD 178
>sp|Q5M786|WDR5_XENTR WD repeat-containing protein 5 OS=Xenopus
tropicalis OX=8364 GN=wdr5 PE=2 SV=1
Length=334
Score = 34.3 bits (77), Expect = 4.7, Method: Composition-based stats.
Identities = 14/92 (15%), Positives = 35/92 (38%), Gaps = 6/92 (7%)
Query 50 CMTVHDK--FLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDG 106
C + + + G+ V + DV+ G + ++ + + G + S DG
Sbjct 134 CCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG 193
Query 107 KVQVFGLYSGE---EFHETFDCPIKIIAVHPH 135
+++ SG+ + + P+ + P+
Sbjct 194 LCRIWDTASGQCLKTLIDDDNPPVSFVKFSPN 225
>sp|B8D737|QUEA_BUCAT S-adenosylmethionine:tRNA ribosyltransferase-isomerase
OS=Buchnera aphidicola subsp. Acyrthosiphon pisum
(strain Tuc7) OX=561501 GN=queA PE=3 SV=1
Length=357
Score = 34.3 bits (77), Expect = 4.8, Method: Composition-based stats.
Identities = 14/40 (35%), Positives = 25/40 (63%), Gaps = 0/40 (0%)
Query 121 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMN 160
+FD P +I+ HP+F+RS+C+ V G ++F + + N
Sbjct 6 FSFDLPKSLISFHPYFIRSTCRLMVMYGHTGMIFHKRFFN 45
>sp|P57232|QUEA_BUCAI S-adenosylmethionine:tRNA ribosyltransferase-isomerase
OS=Buchnera aphidicola subsp. Acyrthosiphon pisum
(strain APS) OX=107806 GN=queA PE=3 SV=1
Length=357
Score = 34.3 bits (77), Expect = 4.8, Method: Composition-based stats.
Identities = 14/40 (35%), Positives = 25/40 (63%), Gaps = 0/40 (0%)
Query 121 ETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMN 160
+FD P +I+ HP+F+RS+C+ V G ++F + + N
Sbjct 6 FSFDLPKSLISFHPYFIRSTCRLMVMYGHTGMIFHKRFFN 45
>sp|C4JPW9|LIS12_UNCRE Nuclear distribution protein PAC1-2 OS=Uncinocarpus
reesii (strain UAMH 1704) OX=336963 GN=PAC1-2 PE=3
SV=1
Length=459
Score = 34.3 bits (77), Expect = 4.9, Method: Composition-based stats.
Identities = 12/71 (17%), Positives = 28/71 (39%), Gaps = 0/71 (0%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
+F+A G+ + L D G + ++ G+++ S+D ++ + L
Sbjct 322 AAEFMATGSRDKTIKLWDAHGRCLGTLIGHDNWVRALAFHPGGKYLLSVSDDKTLRCWDL 381
Query 114 YSGEEFHETFD 124
G + +T
Sbjct 382 SQGGKCVKTLK 392
>sp|C0S902|LIS1_PARBP Nuclear distribution protein PAC1 OS=Paracoccidioides
brasiliensis (strain Pb03) OX=482561 GN=PAC1 PE=3
SV=2
Length=478
Score = 34.3 bits (77), Expect = 4.9, Method: Composition-based stats.
Identities = 14/100 (14%), Positives = 38/100 (38%), Gaps = 6/100 (6%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
+++A G+ + + D +G + + + ++ G+++ S+D ++ + L
Sbjct 326 SAEYVATGSRDKSIRIWDARGTLIKTLIGHDNWVRALAFHPGGKYLLSVSDDKTLRCWDL 385
Query 114 YSGEEFHETFD----CPIKIIAVHPHFVRSSCKQFVTGGK 149
+ T I I P+ ++ + V G
Sbjct 386 TQECKCVRTVKDAHGHFISCIRWAPNIIKDAG--VVNGDD 423
>sp|C1GB49|LIS1_PARBD Nuclear distribution protein PAC1 OS=Paracoccidioides
brasiliensis (strain Pb18) OX=502780 GN=PAC1 PE=3
SV=1
Length=478
Score = 34.3 bits (77), Expect = 4.9, Method: Composition-based stats.
Identities = 14/100 (14%), Positives = 38/100 (38%), Gaps = 6/100 (6%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGL 113
+++A G+ + + D +G + + + ++ G+++ S+D ++ + L
Sbjct 326 SAEYVATGSRDKSIRIWDARGTLIKTLIGHDNWVRALAFHPGGKYLLSVSDDKTLRCWDL 385
Query 114 YSGEEFHETFD----CPIKIIAVHPHFVRSSCKQFVTGGK 149
+ T I I P+ ++ + V G
Sbjct 386 TQECKCVRTVKDAHGHFISCIRWAPNIIKDAG--VVNGDD 423
>sp|Q8YTC2|Y2800_NOSS1 Uncharacterized WD repeat-containing protein
alr2800 OS=Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX
2576) OX=103690 GN=alr2800 PE=4 SV=1
Length=1258
Score = 34.7 bits (78), Expect = 5.0, Method: Composition-based stats.
Identities = 15/63 (24%), Positives = 28/63 (44%), Gaps = 1/63 (2%)
Query 56 KFLALGTHYGKVYLLDVQ-GNITQKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLY 114
K LA +H V + DV G ++ ++ GE + S+D V+++ +
Sbjct 1159 KILASASHDQTVRIWDVNTGKCHHICIGHTHLVSSVAFSPDGEVVASGSQDQTVRIWNVK 1218
Query 115 SGE 117
+GE
Sbjct 1219 TGE 1221
>sp|Q8VZM1|NAA15_ARATH N-terminal acetyltransferase A complex
auxiliary subunit NAA15 OS=Arabidopsis thaliana OX=3702 GN=NAA15
PE=1 SV=1
Length=897
Score = 34.7 bits (78), Expect = 5.1, Method: Composition-based stats.
Identities = 45/263 (17%), Positives = 95/263 (36%), Gaps = 24/263 (9%)
Query 501 LKKDSQNKTLLKTLAELYTYDKNYGNALEIYLTLR--HKDVFQLIHKHNL---------- 548
+K D ++ L LY D+ Y A++ Y D +++ +L
Sbjct 70 VKNDIKSHVCWHVLGLLYRSDREYREAIKCYRNALRIDPDNLEILRDLSLLQAQMRDLSG 129
Query 549 FSSIKDKIVLLMDFDSEKAVDMLLDNEDKISIKKVVEELEDRPELQH-VYLHKLFKRDHH 607
F + +++ L + + + K VE LE Y + +H
Sbjct 130 FVETRQQLLTLKPNHRMNWIGFAVSQHLNANASKAVEILEAYEGTLEDDYPPENELIEHT 189
Query 608 KGQRYHEKQISLYAEYDRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSR 667
+ Y + +D+ + H +K +I + ++ E+ V LLS++G
Sbjct 190 EMILYKVSLLEESGSFDKAL------EELH---KKEPKIVDKLSYKEQEVSLLSKVGRLE 240
Query 668 SALKMIMEEL-HDVDKAIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILL 726
A K+ L + D Q L+ + YS D+ + L ++
Sbjct 241 EANKLYRVLLSMNPDNYRYHEGLQKCLGLYSESGQYSSDQIEKLNALYQSLSEQYTRSSA 300
Query 727 IHRIK-EGMEIPNLRDSLVKILQ 748
+ RI + ++ N ++++ K ++
Sbjct 301 VKRIPLDFLQDENFKEAVAKYIK 323
>sp|Q9I9H8|APAF_DANRE Apoptotic protease-activating factor 1 OS=Danio
rerio OX=7955 GN=apaf1 PE=2 SV=1
Length=1261
Score = 34.7 bits (78), Expect = 5.1, Method: Composition-based stats.
Identities = 17/70 (24%), Positives = 34/70 (49%), Gaps = 1/70 (1%)
Query 49 SCMTVHDKFLALGTHYGKVYLLDVQGNITQ-KFDVSPVKINQISLDESGEHMGVCSEDGK 107
SC++ + F+ALG+ G V +++V + K ++ + E + SED
Sbjct 972 SCISRNAAFVALGSEDGTVQVIEVPSSKASVKLSGHTKTVHHCQFTDDCEILITSSEDST 1031
Query 108 VQVFGLYSGE 117
++V+ +GE
Sbjct 1032 IRVWKWRTGE 1041
>sp|P87119|MU145_SCHPO RING finger protein mug145 OS=Schizosaccharomyces
pombe (strain 972 / ATCC 24843) OX=284812 GN=mug145
PE=1 SV=1
Length=309
Score = 34.3 bits (77), Expect = 5.2, Method: Composition-based stats.
Identities = 18/57 (32%), Positives = 28/57 (49%), Gaps = 7/57 (12%)
Query 783 VLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLP--MPSMNSAAQFCNI 837
+L DEE+ C C +D A + V C H+FH +C+ M +M ++ CN
Sbjct 197 LLEDEEDFCIICY-----ADYAFDDILRVLPCEHVFHTQCIDTWMTTMKASCPLCNE 248
>sp|Q6DFB8|TTC37_XENLA Tetratricopeptide repeat protein 37 OS=Xenopus
laevis OX=8355 GN=ttc37 PE=2 SV=1
Length=1564
Score = 34.7 bits (78), Expect = 5.3, Method: Composition-based stats.
Identities = 46/258 (18%), Positives = 92/258 (36%), Gaps = 24/258 (9%)
Query 406 VERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQL--KAISPYLPRGDPVLKPLIYEM 463
+ DY ++C+ +L + V+ +L + R ++P ++
Sbjct 17 IRNKDYKEVLKQCKAVLKLEKNNYNAWVFIGLAASELEQPDQAQAAYRKAVEIEPD--QL 74
Query 464 ILHEFLESDYEGFATL-IREWPGDLYNNSVIVQAVRDHLKKDSQNKTLLKTLAELYTYDK 522
+ + L + YE +E ++Y + + D K + K L++LY +K
Sbjct 75 LAWQGLGNLYEKVNQKDFKEDLPNVYQKLLELYRSSDKQKWYE----ICKKLSDLYQQEK 130
Query 523 NYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMD----FDSEKAVDMLLDNEDKI 578
NY A + L + I + L+ K LL + D+E +L E I
Sbjct 131 NYVPAAHTWHQLIKMKEDESIKSNELYPLWKRMTELLSEDVEKLDNETQELLLNAFESAI 190
Query 579 SIKKVVEELEDRPELQHVYLHKL--FKRDHHKGQRYHEKQISLYAEYDRPNLLPFLRDST 636
+ + E + QH Y+ L + K ++ E I++Y + P +
Sbjct 191 PCIEEIPSEEHQMLYQH-YITCLSKLPLEEAKLKKVCENMITVY----PSLIYPLKVLAL 245
Query 637 HC----PLEKALEICQQR 650
H + + C +
Sbjct 246 HYIKSGDITEEAICCYSK 263
>sp|Q09485|RAPSN_CAEEL 43 kDa receptor-associated protein of the
synapse homolog OS=Caenorhabditis elegans OX=6239 GN=rpy-1
PE=1 SV=1
Length=596
Score = 34.3 bits (77), Expect = 5.3, Method: Composition-based stats.
Identities = 14/68 (21%), Positives = 24/68 (35%), Gaps = 4/68 (6%)
Query 774 KMHRTQMKGVLVDEENICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQ 833
+ R + + + C C K S+ C H+FH++CL + Q
Sbjct 357 ETARRAASRLTQEMQLFCNFCGQ----RYGLKDESLQALRCSHIFHEKCLHTYLLQRTDQ 412
Query 834 FCNICSAK 841
C C +
Sbjct 413 TCPKCRCR 420
>sp|B6HP56|LIS11_PENRW Nuclear distribution protein nudF 1 OS=Penicillium
rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951
/ Wisconsin 54-1255) OX=500485 GN=nudF-1 PE=3 SV=1
Length=458
Score = 34.3 bits (77), Expect = 5.4, Method: Composition-based stats.
Identities = 10/55 (18%), Positives = 23/55 (42%), Gaps = 0/55 (0%)
Query 54 HDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVCSEDGKV 108
+F+A G+ + L D +GN + + + G+++ S+D +
Sbjct 326 SAEFVATGSRDKTIRLWDTRGNCIKTLVGHDNWVRSLVFHPGGKYLLSVSDDKTL 380
>sp|A8ID74|BOP1_CHLRE Ribosome biogenesis protein BOP1 homolog
OS=Chlamydomonas reinhardtii OX=3055 GN=CHLREDRAFT_111274 PE=3
SV=2
Length=797
Score = 34.3 bits (77), Expect = 5.5, Method: Composition-based stats.
Identities = 19/89 (21%), Positives = 35/89 (39%), Gaps = 5/89 (6%)
Query 47 AASCMTVH--DKFLALGTHYGKV--YLLDVQGNITQKFDVSPVKINQISLDESGEHMGVC 102
SC+ +H + +G+ +V Y LD+ + ++ S
Sbjct 671 VLSCLALHPGGDHVLVGSDDKRVAWYDLDLSTKPYKALRYHSAPPRAVAFHRSYPLFASA 730
Query 103 SEDGKVQVF-GLYSGEEFHETFDCPIKII 130
++DG VQVF G+ + P+KI+
Sbjct 731 ADDGTVQVFHGMVYADLLTNPLIVPVKIL 759
>sp|Q0BTY8|LEXA_GRABC LexA repressor OS=Granulibacter bethesdensis
(strain ATCC BAA-1260 / CGDNIH1) OX=391165 GN=lexA PE=3
SV=1
Length=242
Score = 33.9 bits (76), Expect = 5.7, Method: Composition-based stats.
Identities = 27/116 (23%), Positives = 46/116 (40%), Gaps = 17/116 (15%)
Query 32 YERLSNGVTEILQKDAASCMTVHDKFLALGTHYGKVYLLDVQGNIT---QKFDVSPVKIN 88
Y R++ G+ +D ++ ++V L G H Y L+V G+ FD V I
Sbjct 123 YGRIAAGMPIEALRDTSAYLSVPIDMLGNGEH----YALEVAGDSMIDAGIFDGDTVIIQ 178
Query 89 QISLDESGEHMGVCSEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQF 144
Q L +E+G++ V + E + K +A+ P R + F
Sbjct 179 QSDL----------AENGQIVVALIDDTEVTLKRLRRRGKSVALEPANERHETRIF 224
>sp|Q0USG2|CIAO1_PHANO Probable cytosolic iron-sulfur protein
assembly protein 1 OS=Phaeosphaeria nodorum (strain SN15 / ATCC
MYA-4574 / FGSC 10173) OX=321614 GN=CIA1 PE=3 SV=1
Length=443
Score = 34.3 bits (77), Expect = 5.9, Method: Composition-based stats.
Identities = 14/63 (22%), Positives = 26/63 (41%), Gaps = 5/63 (8%)
Query 78 QKFDVSPVKINQISLDESGEHMGVCSEDGKVQVFGLYSGEEFH-----ETFDCPIKIIAV 132
D +I +S +G+++ CS D V ++ + F + D +K +A
Sbjct 131 CILDGHESEIKSLSWSPTGQYLATCSRDKSVWIWEELEDDNFETVAVLQEHDGDVKCVAW 190
Query 133 HPH 135
HP
Sbjct 191 HPE 193
>sp|F1LTR1|WDR26_RAT WD repeat-containing protein 26 OS=Rattus
norvegicus OX=10116 GN=Wdr26 PE=3 SV=2
Length=514
Score = 33.9 bits (76), Expect = 7.1, Method: Composition-based stats.
Identities = 24/141 (17%), Positives = 58/141 (41%), Gaps = 25/141 (18%)
Query 81 DVSPVKINQISLDESGEHMGVCSED--GKVQVFGLYSGE---EFHETFDCPIKIIAVHPH 135
+ ++ I+ ++ C D ++ ++ + +GE + ++ + + +A +P
Sbjct 251 EGHAYGVSYIAWSPDDSYLVACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPD 310
Query 136 FVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLI--AWANNMGVK 193
K+FVTGG++ ++ + +GN+ W G + W + G
Sbjct 311 -----GKRFVTGGQRGQFYQ------------CDLDGNLLD-SWEGVRVQCLWCLSDGKT 352
Query 194 IFDIISKQRITNVPRDDISLR 214
+ + QRI +D++ R
Sbjct 353 VLASDTHQRIRGYNFEDLTDR 373
>sp|Q8C6G8|WDR26_MOUSE WD repeat-containing protein 26 OS=Mus
musculus OX=10090 GN=Wdr26 PE=1 SV=3
Length=641
Score = 33.9 bits (76), Expect = 7.3, Method: Composition-based stats.
Identities = 23/141 (16%), Positives = 58/141 (41%), Gaps = 25/141 (18%)
Query 81 DVSPVKINQISLDESGEHMGVCSED--GKVQVFGLYSGE---EFHETFDCPIKIIAVHPH 135
+ ++ I+ ++ C D ++ ++ + +GE + ++ + + +A +P
Sbjct 378 EGHAYGVSYIAWSPDDSYLVACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSVAWNPD 437
Query 136 FVRSSCKQFVTGGKKLLLFERSWMNRWKSAVLHEGEGNIRSVKWRGHLI--AWANNMGVK 193
K+FVTGG++ ++ + +GN+ W G + W + G
Sbjct 438 -----GKRFVTGGQRGQFYQ------------CDLDGNLLD-SWEGVRVQCLWCLSDGKT 479
Query 194 IFDIISKQRITNVPRDDISLR 214
+ + QR+ +D++ R
Sbjct 480 VLASDTHQRVRGYNFEDLTDR 500
>sp|P53804|TTC3_HUMAN E3 ubiquitin-protein ligase TTC3 OS=Homo
sapiens OX=9606 GN=TTC3 PE=1 SV=2
Length=2025
Score = 33.9 bits (76), Expect = 9.1, Method: Composition-based stats.
Identities = 13/52 (25%), Positives = 17/52 (33%), Gaps = 8/52 (15%)
Query 791 CESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKN 842
CE C K +V V C H +HK C C C ++
Sbjct 1957 CEICHEVF------KSKNVRVLKCGHKYHKGCFKQWL--KGQSACPACQGRD 2000
>sp|P25635|PWP2_YEAST Periodic tryptophan protein 2 OS=Saccharomyces
cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=PWP2
PE=1 SV=2
Length=923
Score = 33.9 bits (76), Expect = 9.4, Method: Composition-based stats.
Identities = 24/115 (21%), Positives = 47/115 (41%), Gaps = 7/115 (6%)
Query 31 KYE-RLSNGVTEILQKDAASCMTVH--DKFLALGTHYGKVYLLDVQG-NITQKFDVSPVK 86
KY R++ + C+T H + LA+G G+ L D+ + Q+ +
Sbjct 245 KYSWRITKKHFFYANQAKVKCVTFHPATRLLAVGFTSGEFRLYDLPDFTLIQQLSMGQNP 304
Query 87 INQISLDESGEHMGVCSED-GKVQVFGLYSGEEFHETFDCP--IKIIAVHPHFVR 138
+N +S++++GE + S G++ V+ S + +A P R
Sbjct 305 VNTVSVNQTGEWLAFGSSKLGQLLVYEWQSESYILKQQGHFDSTNSLAYSPDGSR 359
Lambda K H a alpha
0.317 0.131 0.334 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0402 0.140 1.90 42.6 43.6
Effective search space used: 98193838406
Database: uniprot_sprot.fasta
Posted date: Jun 30, 2025 8:32 PM
Number of letters in database: 207,922,125
Number of sequences in database: 573,661
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40