Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V 1 M -1 -2 -3 -4 -2 -1 -3 -3 -2 1 2 -2 8 0 -3 -2 -1 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.72 0.07 2 P 1 -2 -1 -2 -2 -1 -1 -2 -2 -1 0 -1 -1 -2 6 1 2 -3 -2 -1 9 0 0 0 0 0 0 0 0 0 13 0 0 0 42 18 18 0 0 0 0.67 0.03 3 D -1 -2 2 3 -3 -1 1 2 2 -2 -1 -1 -1 -1 -2 -1 -1 -2 1 -2 0 0 13 30 0 0 9 18 8 0 13 0 0 0 0 0 0 0 10 0 0.24 0.02 4 T 1 -1 0 -1 -1 -1 -1 -1 -2 -2 -2 -1 -1 -3 2 2 4 -3 -2 -1 15 0 0 0 0 0 0 0 0 0 0 0 0 0 9 25 51 0 0 0 0.40 0.03 5 M 2 -2 -1 -2 -1 -1 -1 -1 -1 0 -1 -1 1 1 -2 1 3 -1 2 0 25 0 0 0 0 0 0 0 0 0 0 0 6 8 0 8 32 0 12 9 0.18 0.02 6 L -1 -3 -4 -4 -1 -3 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 15 71 0 0 0 0 0 0 0 0 14 0.44 0.03 7 P 0 -2 -2 -2 -2 -1 -1 -2 -2 -1 1 -1 0 -2 5 2 0 -3 -2 -1 9 0 0 0 0 0 0 0 0 0 27 0 0 0 39 26 0 0 0 0 0.58 0.03 8 A 2 -2 -2 -3 -1 -2 -2 -2 -3 1 2 -2 1 -1 -2 0 2 -3 -2 2 28 0 0 0 0 0 0 0 0 0 29 0 0 0 0 0 19 0 0 24 0.18 0.02 9 C 1 -3 -2 -3 8 -3 -3 -2 -3 -1 -1 -3 -1 -3 -3 0 0 -3 -3 -1 11 0 0 0 67 0 0 0 0 0 7 0 0 0 0 7 8 0 0 0 0.89 0.06 10 F 0 -3 -3 -4 2 -3 -3 -3 -2 1 2 -3 1 4 -3 -2 -1 -1 1 1 11 0 0 0 6 0 0 0 0 6 27 0 0 37 0 0 0 0 0 13 0.29 0.03 11 L 0 -3 -3 -4 -1 -2 -3 -3 -3 2 3 -3 1 1 -3 -2 -1 -2 -1 2 7 0 0 0 0 0 0 0 0 5 63 0 0 7 0 0 0 0 0 17 0.34 0.03 12 G -1 -3 -2 -3 4 -2 -3 3 -1 -1 0 -2 -1 2 -3 0 -1 -1 3 -1 0 0 0 0 18 0 0 29 0 0 17 0 0 12 0 9 0 0 16 0 0.26 0.02 13 L 0 -2 -3 -3 -2 -2 -3 -1 -3 2 3 -2 1 0 -3 0 -1 3 -1 0 6 0 0 0 0 0 0 5 0 12 61 0 0 0 0 9 0 6 0 0 0.28 0.03 14 L -1 -2 -3 -3 -2 -2 -3 -3 -3 1 4 -3 2 0 -3 0 -1 -2 -2 0 0 0 0 0 0 0 0 0 0 0 88 0 0 0 0 12 0 0 0 0 0.47 0.06 15 A 3 -2 -1 -2 2 -1 -1 -1 -2 -2 -1 -1 -1 -2 -1 3 0 -3 -2 -1 55 0 0 0 6 0 0 0 0 0 5 0 0 0 0 34 0 0 0 0 0.36 0.05 16 F 0 -2 -3 -3 -2 1 -2 -3 -2 1 3 -2 1 2 -3 -2 -1 -2 0 2 5 0 0 0 0 12 0 0 0 0 46 0 0 13 0 0 0 0 0 24 0.23 0.03 17 S 1 -2 -1 -2 5 -1 -1 -2 -2 -2 -2 -1 -2 -3 -2 3 3 -3 -2 -1 6 0 0 0 16 0 0 0 0 0 0 0 0 0 0 42 35 0 0 0 0.50 0.08 18 S 0 -1 2 1 -2 3 0 -1 -1 -3 -3 0 -2 -3 -2 4 1 -3 -2 -3 0 0 9 6 0 22 0 0 0 0 0 0 0 0 0 61 3 0 0 0 0.49 0.09 19 A 5 -2 -2 -3 -1 -2 -2 2 -3 -2 -3 -2 -2 -3 -2 0 -1 -3 -3 -1 87 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0.70 0.13 20 C -2 -5 -4 -5 10 -4 -5 -4 -4 -2 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.30 0.23 21 Y -3 -3 -3 -4 -3 -3 -3 -4 0 -2 -1 -3 -1 6 -4 -3 -3 1 7 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 38 0 0 0 0 62 0 1.23 0.16 22 F -2 -4 -4 -4 -2 -4 -4 -4 -4 5 2 -4 1 3 -4 -3 -2 -2 -1 2 0 0 0 0 0 0 0 0 0 71 13 0 0 16 0 0 0 0 0 0 0.61 0.11 23 Q -1 3 -1 -1 -3 5 0 1 -1 -4 -3 1 -2 -4 -2 1 0 -3 -2 -3 0 24 0 0 0 49 0 13 0 0 0 0 0 0 0 10 4 0 0 0 0.55 0.11 24 N -3 -1 7 0 -4 -1 -1 -1 0 -4 -5 -1 -3 -4 -3 0 -1 -5 -3 -4 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.38 0.19 25 C -2 -5 -4 -5 10 -4 -5 -4 -4 -2 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.30 0.23 26 P -2 -3 -3 -3 -4 -3 -2 -4 -3 -3 0 -2 -2 -4 8 -2 -2 -5 -4 -3 0 0 0 0 0 0 0 0 0 0 14 0 0 0 86 0 0 0 0 0 1.99 0.22 27 R -2 5 2 -1 -3 0 1 -3 -1 0 -1 2 -1 -3 -3 -1 -1 -3 -2 -2 0 45 14 0 0 0 9 0 0 11 8 14 0 0 0 0 0 0 0 0 0.41 0.10 28 G -1 -3 -1 2 -4 -3 -2 6 -3 -5 -5 -2 -4 -4 -3 -1 -2 -4 -4 -4 0 0 0 14 0 0 0 86 0 0 0 0 0 0 0 0 0 0 0 0 1.26 0.17 29 G -1 -3 -1 -2 -3 -3 -3 6 -3 -5 -4 -3 -4 -4 -3 -1 -3 -3 -4 -4 0 0 0 0 0 0 0 92 0 0 0 0 0 0 0 0 0 0 0 0 1.32 0.19 30 K -2 1 -1 -1 -4 0 2 -3 -2 -4 -3 6 -2 -4 -2 -1 -2 -4 -3 -3 0 0 0 0 0 0 14 0 0 0 0 78 0 0 0 0 0 0 0 0 0.77 0.18 31 R -3 7 -2 -3 -4 0 -1 -3 -1 -4 -3 1 -2 -4 -3 -2 -2 -4 -3 -4 0 92 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.22 0.22 32 A 3 -2 1 3 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 -2 2 0 -3 -2 -2 41 0 6 21 0 0 1 1 0 0 1 1 0 0 0 26 1 0 0 1 0.41 0.13 33 M 0 -2 -3 -3 -2 -1 -2 -3 -2 2 2 -2 2 0 -3 -2 -1 -2 1 3 6 0 0 0 0 4 1 1 0 7 16 1 5 4 0 1 2 0 6 45 0.26 0.09 34 S -1 -1 0 3 -2 0 0 -1 3 -1 0 -1 0 -2 3 0 -1 -3 -1 -2 4 1 1 24 0 6 1 3 12 3 13 1 4 1 17 9 1 0 0 1 0.26 0.07 35 D -1 -2 0 5 -4 -1 3 -2 -2 -3 -3 -1 3 -4 -2 0 0 -4 -3 -3 5 0 0 53 0 0 22 0 0 0 0 0 13 0 0 3 5 0 0 0 0.70 0.16 36 L 0 0 -2 -3 -2 -2 -2 -1 -3 2 2 -2 1 0 -1 -1 2 -3 -2 2 4 6 0 0 0 0 0 6 0 13 21 0 5 3 3 2 23 0 0 16 0.14 0.06 37 E 0 -1 -1 2 -3 2 2 0 -1 -3 -3 0 -2 -3 3 0 0 -3 0 -2 7 0 0 18 0 18 16 8 0 0 0 2 0 0 14 3 5 0 6 3 0.33 0.08 38 L -1 -2 -2 -2 -2 -1 -2 0 -2 1 1 -2 0 -1 2 1 1 -3 -2 1 1 0 0 0 0 3 0 9 0 6 24 0 2 0 13 14 10 0 0 17 0.16 0.06 39 R -2 6 -1 -2 -4 0 -1 -3 2 -4 -3 2 -2 -4 -1 -1 1 -4 -2 -3 0 67 0 0 0 0 0 0 7 0 0 10 0 0 3 0 13 0 0 0 0.86 0.19 40 Q 0 0 -1 -1 -3 4 2 -2 -1 -3 -3 3 -2 -4 2 0 -1 -3 -3 -3 6 0 0 0 0 31 16 0 0 0 0 27 0 0 11 7 2 0 0 0 0.53 0.13 41 C 0 -3 -3 -4 10 -3 -3 -3 -3 -2 -2 -3 -2 -3 -3 -2 -2 -3 -3 -2 9 1 1 1 79 1 1 1 0 1 1 1 0 0 1 1 1 0 0 1 1.71 0.24 42 L 0 -2 -3 -3 -2 -2 -2 -3 -2 1 2 -2 7 -1 -3 -2 -1 -2 -2 1 8 1 1 1 0 1 1 1 0 7 21 1 51 0 1 1 1 0 0 4 0.53 0.15 43 P 1 -2 -2 -2 -2 -1 -1 -2 -2 -2 -2 0 -2 2 6 1 0 -2 -1 -2 12 0 0 0 0 0 0 0 0 0 0 5 0 16 45 17 5 0 0 0 0.72 0.05 44 C -1 -4 -3 -4 10 -4 -4 -3 -4 -2 -2 -4 -2 -3 -4 -2 -2 -3 -3 -1 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.79 0.15 45 G 0 -1 -1 -1 -2 -1 -1 5 -2 -2 -2 0 2 -2 -2 1 -1 -2 -2 -2 1 0 0 0 0 0 1 57 0 0 1 9 14 0 0 13 1 0 0 1 0.47 0.05 46 P -1 -2 1 -1 -2 -1 -1 -2 -1 -2 -1 -1 -1 -1 6 -1 -1 -1 2 -2 2 1 9 1 0 1 1 2 0 1 9 1 0 1 51 2 1 0 15 1 0.77 0.04 47 G -1 0 -1 0 4 -1 -1 5 -2 -3 -3 -1 -2 -3 -2 -1 -2 -3 -3 -3 1 9 1 4 12 1 4 62 0 1 1 1 0 0 1 1 1 0 0 1 0.65 0.08 48 G -1 -2 3 3 -3 -1 0 4 -1 -3 -3 -1 -3 -3 -2 1 -1 -3 -3 -3 1 0 19 19 0 0 3 37 0 0 1 0 0 0 0 16 0 0 0 1 0.48 0.06 49 K -1 3 -1 -2 -3 2 -1 -3 -1 -2 -2 3 -1 3 -2 -1 -1 -2 0 -1 3 25 0 0 0 14 0 0 0 0 0 25 0 24 0 0 4 0 0 6 0.32 0.07 50 G -1 -3 -1 -2 -3 -2 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -3 -4 1 0 0 0 0 0 0 93 0 0 1 0 0 0 0 1 0 0 0 0 1.27 0.13 51 R -2 5 1 -1 -3 4 0 -2 2 -3 -2 1 -1 -3 -2 -1 -1 -3 -2 -3 1 45 6 0 0 34 0 1 6 0 3 0 0 0 0 1 0 0 0 0 0.61 0.10 52 C -2 -5 -4 -5 11 -4 -5 -4 -4 -3 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.35 0.22 53 F -2 -3 -4 -4 -2 -3 -4 -4 -3 1 0 -4 0 6 -4 -3 -2 -1 2 3 0 0 0 0 0 0 0 0 0 0 4 0 0 52 0 0 0 0 3 41 0.67 0.11 54 G 0 -3 -1 -2 -3 -3 -3 6 -3 -5 -5 -2 -4 -4 -3 -1 -2 -3 -4 -4 5 0 0 0 0 0 0 95 0 0 0 0 0 0 0 0 0 0 0 0 1.38 0.14 55 P -2 -3 -3 -3 -4 -2 -2 -3 -3 -4 -4 -2 -4 -5 8 -2 -2 -5 -4 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.49 0.19 56 S 0 1 3 -1 -2 0 -1 0 3 -3 -3 0 -2 -3 -2 4 0 -4 -2 -3 0 10 16 0 0 4 0 6 12 0 0 0 0 0 0 51 0 0 0 0 0.43 0.09 57 I -2 -4 -4 -4 -2 -4 -4 -5 -4 6 1 -3 0 -1 -4 -3 0 -4 -2 2 0 0 0 0 0 0 0 0 0 87 0 0 0 0 0 0 5 0 0 8 0.77 0.13 58 C -2 -5 -4 -5 11 -4 -5 -4 -4 -3 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.35 0.22 59 C -2 -5 -4 -5 11 -4 -5 -4 -4 -3 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.35 0.22 60 A 1 -3 -1 -2 -3 -3 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 10 0 0 0 0 0 0 90 0 0 0 0 0 0 0 0 0 0 0 0 1.27 0.13 61 D 1 -1 -1 3 -3 1 3 0 -1 -2 -1 0 -2 -3 0 0 -1 -3 -2 -2 15 0 0 18 0 4 34 8 0 0 7 3 0 0 3 1 0 0 0 2 0.28 0.05 62 E 0 0 -1 2 -3 0 3 2 -1 -3 -1 0 -2 -3 0 0 -1 -3 -3 -2 9 7 0 10 0 0 38 23 0 0 8 0 0 0 3 2 0 0 0 0 0.33 0.06 63 L -1 0 -3 -3 -2 -2 -2 -3 -2 1 3 -1 2 1 -2 -2 -1 -2 -1 1 1 5 0 1 0 0 1 1 0 7 56 6 6 6 1 1 4 0 0 4 0.26 0.05 64 G -1 -3 -1 -2 -3 -3 -3 6 -3 -4 -4 -2 -3 -4 -3 -1 -2 -3 -4 -4 0 0 0 0 0 0 0 96 0 0 0 0 0 0 0 0 0 0 0 0 1.36 0.14 65 C -2 -5 -4 -5 10 -4 -5 0 -4 -3 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 92 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 2.04 0.20 66 F -2 -2 -2 -2 -3 -1 2 0 1 -1 1 -2 -1 3 -3 -2 -2 3 4 -1 0 0 0 0 0 0 24 8 4 0 21 0 0 19 0 0 0 5 21 0 0.30 0.07 67 V -1 0 -3 -4 -2 -2 -3 -4 -3 2 2 -2 5 0 -3 -2 -1 -3 -1 3 0 8 0 0 0 0 0 0 0 10 9 0 36 4 0 0 0 0 0 33 0.40 0.09 68 G -1 -3 -1 -2 -4 -3 -3 7 -3 -5 -5 -3 -4 -4 -3 -1 -3 -4 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.50 0.15 69 T 0 -2 -1 -2 -2 -1 -1 0 -2 -2 -3 -1 -2 -3 -2 3 5 -3 -3 -1 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 33 60 0 0 0 0.61 0.12 70 A 2 -2 -2 -2 -2 -1 -1 0 -2 -2 -2 -1 -2 -3 5 0 0 -3 -3 -1 34 0 0 0 0 0 4 8 0 0 4 0 0 0 34 5 7 0 0 5 0.57 0.07 71 E -2 -1 -1 1 3 1 6 -3 -1 -4 -4 0 -3 -4 -2 -1 -2 2 -3 -3 0 0 0 5 8 0 84 0 0 0 0 0 0 0 0 0 0 4 0 0 0.95 0.14 72 A 4 -2 -2 -2 -1 -1 -2 -1 -2 0 -1 -1 0 -3 -2 1 3 -3 -2 0 55 0 0 0 0 0 0 0 0 8 0 0 4 0 0 2 32 0 0 0 0.41 0.10 73 L 1 -1 2 0 -2 0 0 -2 -2 0 2 -1 1 -1 -2 0 -1 -3 -2 0 22 4 15 5 0 2 6 0 0 0 32 0 3 0 0 4 0 0 0 8 0.11 0.04 74 R -1 5 -1 -2 -3 0 -1 1 0 -2 -2 1 1 -3 -3 0 0 -3 -2 0 0 55 0 0 0 0 0 11 3 0 0 4 8 0 0 5 4 0 0 10 0.43 0.09 75 C -2 -5 -4 -5 11 -4 -5 -4 -4 -3 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.35 0.22 76 Q 0 1 -1 -1 -3 4 1 -2 1 -1 -1 1 1 -2 -2 0 -1 -3 -2 0 10 5 0 0 0 44 5 0 4 3 2 8 6 2 0 3 0 0 0 9 0.31 0.08 77 E -2 1 -1 0 -5 2 6 -2 -1 -4 -4 1 -3 -4 -2 -1 -2 -4 -3 -3 0 8 0 0 0 4 80 2 0 0 0 6 0 0 0 0 0 0 0 0 0.90 0.13 78 E -2 -1 -1 1 -5 1 7 -3 -1 -4 -4 0 -3 -4 -2 -1 -2 -4 -3 -4 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 1.26 0.17 79 N -2 -1 6 3 -4 -1 0 -1 -1 -3 -4 -1 -3 -4 -3 0 0 -5 -3 -4 0 0 73 17 0 0 4 0 0 1 0 0 0 0 0 2 2 0 0 0 0.94 0.13 80 Y -2 -2 -2 0 -3 -1 3 -3 1 -2 0 -2 -1 3 -3 -2 -2 0 6 -2 0 0 0 4 0 0 30 0 3 0 8 0 0 10 0 0 0 0 46 0 0.60 0.11 81 L -1 -2 0 2 -2 -2 -1 -3 2 0 3 -2 1 -1 -3 1 -1 -3 -2 -1 0 0 4 15 0 0 0 0 8 0 57 0 2 0 0 15 0 0 0 0 0.26 0.08 82 P -1 -3 -2 -2 -3 -2 -2 -3 -3 -3 -2 -2 -3 -4 8 1 -1 -4 -4 -3 0 0 0 0 0 0 0 0 0 0 5 0 0 0 79 14 2 0 0 0 1.74 0.15 83 S 0 -2 -1 -1 -2 -1 0 -2 -2 1 -1 -1 -1 -2 -2 3 3 -3 -2 1 3 0 0 0 0 0 8 0 0 15 0 0 0 0 0 45 21 0 0 8 0.29 0.08 84 P -2 -3 -3 -3 -4 -2 -2 -3 -3 -4 -4 -2 -4 -5 8 -2 -2 -5 -4 -4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.49 0.19 85 C -2 -5 -4 -5 11 -4 -5 -4 -4 -3 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.35 0.22 86 Q 0 2 -1 -1 -4 5 3 -2 3 -3 -2 1 -1 -3 -2 -1 -1 -3 -2 -3 6 9 0 0 0 45 22 0 9 0 4 5 0 0 0 0 0 0 0 0 0.55 0.10 87 S 2 -2 -1 -2 -1 -2 -2 0 -2 1 -1 -2 -1 -2 -1 2 1 -3 -2 3 18 0 0 0 0 0 0 8 0 3 0 0 0 0 2 25 8 0 0 35 0.21 0.06 88 G 0 -3 -1 -2 -3 -2 -3 5 -2 -2 -1 -1 -2 2 -3 0 -2 -2 -1 -2 4 0 0 0 0 0 0 63 0 0 5 4 0 16 0 6 0 0 0 3 0.62 0.09 89 Q -1 0 -1 -2 -4 2 -1 6 -2 -4 -4 -1 -3 -4 -3 -1 -2 -3 -3 -4 0 7 0 0 0 19 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0.96 0.12 90 K -1 3 -1 0 -3 2 1 -2 -1 -3 -3 4 -2 -3 -2 1 -1 2 -2 -3 0 24 0 4 0 13 4 0 0 0 0 41 0 0 0 11 0 4 0 0 0.50 0.08 91 A 0 1 -2 -1 -3 -1 -1 -2 3 -2 -2 -1 -1 -3 6 0 -1 -4 -2 -1 8 9 0 3 0 0 0 0 14 0 4 0 2 0 45 8 0 0 0 7 0.75 0.09 92 C -2 -5 -4 -5 11 -4 -5 -4 -4 -3 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.35 0.22 93 G 0 -3 3 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -3 0 -2 -4 -4 -4 3 0 20 0 0 0 0 74 0 0 0 0 0 0 0 2 0 0 0 0 1.01 0.12 94 S 0 -2 2 0 -2 -1 -1 -1 -1 -1 0 -1 -1 -2 -2 3 1 -3 0 0 3 0 11 5 0 0 0 0 0 3 11 0 0 0 0 51 4 0 3 9 0.24 0.07 95 G 0 -2 2 1 -3 0 2 3 3 -3 -3 -1 -3 -3 -2 0 0 -3 -2 -3 9 0 14 5 0 0 19 35 12 0 0 0 0 0 0 0 6 0 0 0 0.40 0.06 96 G 0 -3 -1 -2 -3 -3 -3 6 -3 -5 -4 -2 -4 -4 -3 -1 -1 -3 -4 -4 2 0 0 0 0 0 0 95 0 0 0 0 0 0 0 0 3 0 0 0 1.35 0.14 97 R -2 4 4 -1 -3 0 -1 -2 2 -1 -2 1 -2 -3 0 0 -1 -4 -2 -2 0 42 29 0 0 0 0 0 6 8 2 4 0 0 4 6 0 0 0 0 0.44 0.09 98 C -2 -5 -4 -5 11 -4 -5 -4 -4 -3 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.35 0.22 99 A 4 -3 -3 -3 -1 -2 -2 -1 -3 0 -1 -2 -1 -2 -2 0 -1 -3 -2 3 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 0.50 0.11 100 A 5 -1 -2 -2 -1 -1 -2 0 -2 -2 -2 -1 -2 -3 -2 1 0 -3 -2 0 74 2 0 0 0 0 0 5 0 0 0 0 0 0 0 9 5 0 0 5 0.50 0.10 101 F 0 -2 0 2 -3 -1 -1 -2 -2 0 -2 -1 -2 -1 5 1 -1 -3 0 -1 10 0 6 15 0 0 0 0 0 8 2 0 0 3 38 10 1 0 5 1 0.56 0.07 102 G -1 -3 -1 -2 -4 -3 -3 7 -3 -5 -5 -3 -4 -4 -3 -1 -3 -4 -4 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.50 0.15 103 V -2 -4 -4 -4 -2 -3 -4 -4 -4 5 1 -3 1 -1 -3 -3 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 60 8 0 0 0 0 0 0 0 0 32 0.62 0.10 104 C -2 -5 -4 -5 11 -4 -5 -4 -4 -3 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.35 0.22 105 C -2 -5 -4 -5 11 -4 -5 -4 -4 -3 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.35 0.22 106 N -1 -2 2 3 -2 -1 -1 -1 -2 -1 -2 -1 -2 -3 -2 2 1 -4 -1 1 0 0 14 22 0 0 0 4 0 0 0 0 0 0 0 26 12 0 1 21 0.25 0.06 107 D 0 -2 1 4 -3 -1 1 -2 2 -3 -3 -1 -2 -3 1 2 1 -4 -2 -2 8 0 2 38 0 0 8 0 7 0 0 0 0 0 7 21 7 0 0 2 0.42 0.07 108 E -2 -2 0 5 -4 1 4 -3 -1 -2 -3 -1 -3 -4 -2 -1 -2 -4 -3 0 0 0 0 43 0 2 45 0 0 0 0 0 0 0 0 0 0 0 0 10 0.73 0.11 109 S 1 -2 -1 -1 -2 -1 -1 3 -2 -2 -3 -1 -2 -3 -2 3 4 -3 -3 -2 6 0 0 0 0 0 0 23 0 0 0 0 0 0 0 32 38 0 0 0 0.47 0.09 110 C -2 -5 -4 -5 11 -4 -5 -4 -4 -3 -3 -4 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.35 0.22 111 V 1 -1 -1 -2 -1 -1 -1 -2 0 0 -1 0 0 -2 -2 2 2 -3 -2 2 14 2 0 0 0 0 0 0 3 0 4 4 2 0 0 27 18 0 0 27 0.19 0.06 112 T 1 -2 -3 -3 -1 -2 -3 -3 -3 2 1 -2 3 1 -3 -1 1 -2 -1 2 14 0 0 0 0 0 0 0 0 18 11 0 16 7 0 0 13 0 0 20 0.22 0.05 113 E -2 -2 2 5 -4 0 2 -2 5 -4 -4 -1 -3 -4 -2 0 -2 -4 -2 -4 0 0 10 52 0 0 14 0 20 0 0 0 0 0 0 4 0 0 0 0 0.78 0.11 114 P 1 0 -1 0 -2 1 -1 -2 -2 -2 -1 -1 -2 -3 5 2 0 -3 -3 -1 11 6 0 4 0 11 0 0 0 0 5 0 0 0 31 24 4 0 0 4 0.50 0.08 115 E 1 1 0 1 -2 0 2 0 -1 -2 -1 0 -1 -3 -2 2 1 -3 -2 -1 16 10 4 8 0 0 19 8 0 0 7 0 0 0 0 20 8 0 0 2 0.18 0.04 116 C -2 -5 -4 -5 11 -4 -5 -4 -5 -3 -3 -5 -3 -4 -4 -2 -2 -4 -4 -2 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2.46 0.25 117 R -1 3 -1 1 -3 1 1 -3 1 -1 1 0 0 -2 -2 0 -1 -3 -2 -1 0 28 0 12 0 8 10 0 4 0 26 0 0 0 0 5 3 0 0 5 0.19 0.04 118 E -1 -1 0 4 -3 2 4 -2 -1 -3 -3 1 -2 -3 -2 0 -1 -4 -3 -1 0 0 2 29 0 6 42 0 0 0 0 9 0 0 0 3 0 0 0 7 0.52 0.06 119 G -1 -1 0 3 -3 0 3 3 -1 -3 -3 0 -2 -3 -1 0 -1 -3 -2 -3 1 1 1 21 0 1 35 30 0 1 1 1 0 1 1 1 1 0 1 1 0.42 0.03 120 F 0 -2 -1 1 -2 -1 0 1 -2 0 -1 -1 -1 2 -2 1 1 -2 0 1 4 0 0 12 0 0 5 17 0 0 3 0 0 19 0 12 10 0 0 16 0.09 0.02 121 H -1 0 0 2 -2 0 1 -1 1 -2 -2 0 -1 0 1 1 1 -2 -1 -2 1 5 0 20 0 0 5 4 6 1 3 8 0 6 8 15 16 0 0 1 0.17 0.02 122 R -1 3 1 0 -3 2 3 -2 0 -3 -2 1 -2 -2 -2 0 -1 -2 0 -2 5 29 6 1 0 10 38 1 0 1 1 1 0 0 1 1 1 0 4 1 0.40 0.04 123 R -1 3 0 1 -3 2 2 -2 1 -3 -1 2 -1 -3 0 0 -1 -3 -2 -2 0 31 0 6 0 16 14 0 4 0 6 11 0 0 3 5 0 0 0 0 0.33 0.04 124 A 2 0 -1 1 -1 0 -1 1 -1 0 -1 -1 -1 -2 0 1 0 -2 0 0 28 4 0 10 0 4 0 8 0 5 5 0 0 0 4 14 6 0 4 6 0.10 0.02 125 R -1 3 -1 -1 -3 0 2 2 -1 -2 -3 0 -2 -3 2 1 -1 -3 -3 -2 0 28 0 0 0 0 19 19 0 5 0 0 0 0 12 14 0 0 0 0 0.31 0.05 126 A 2 -2 -1 -1 -1 0 1 -2 -2 0 -1 -1 -1 -2 1 2 0 -3 -2 2 23 0 0 0 0 5 11 0 0 0 5 0 0 0 5 24 0 0 0 28 0.17 0.05 127 S 1 0 0 1 -2 1 1 1 -1 -2 -2 0 -2 -1 0 2 1 -3 -2 -2 8 6 0 10 0 5 11 8 0 0 0 0 0 5 4 28 15 0 0 0 0.20 0.03 128 D 1 -1 0 3 -2 1 2 -2 1 -2 -2 -1 -2 1 1 0 -1 -2 -1 -2 21 0 0 22 0 10 18 0 4 0 0 0 0 11 8 5 0 0 0 0 0.25 0.04 129 R -1 2 -1 0 -3 1 2 1 -1 -3 -3 0 -2 -2 2 2 0 -3 0 -1 0 21 0 4 0 7 15 10 0 0 0 0 0 0 9 25 0 0 4 5 0.25 0.04 130 S 1 0 0 -1 -2 3 1 1 -1 -3 -3 1 -2 -3 -2 3 0 -3 -2 -2 11 0 0 0 0 21 5 11 0 0 0 11 0 0 0 42 0 0 0 0 0.35 0.07 131 N 0 -1 5 3 -3 0 1 0 0 -3 -3 -1 -2 -3 -2 1 -1 -3 -2 -3 11 0 46 17 0 0 10 5 0 0 1 1 0 0 0 6 1 0 0 1 0.44 0.06 132 A 2 -1 -1 -2 -1 0 -1 -1 -2 0 1 -1 1 -1 1 1 1 -2 -1 0 24 1 1 1 0 7 1 1 0 1 22 1 8 1 6 11 11 0 0 4 0.11 0.03 133 T 1 -1 1 -1 -1 -1 -1 1 1 -1 0 -1 -1 -2 -1 1 3 -2 -2 -1 9 0 7 1 0 0 1 11 5 0 10 1 0 0 1 10 41 0 0 1 0.21 0.05 134 Q -1 0 -1 0 -2 2 0 2 -1 -1 0 0 0 -2 -2 0 1 -2 -2 0 1 6 0 6 0 20 1 20 0 0 15 1 0 0 1 5 16 0 0 8 0.12 0.03 135 L -1 -2 -2 -3 -2 -2 -2 -3 1 1 4 -2 3 0 -2 -2 -1 -2 -1 0 6 1 1 1 0 1 1 1 5 1 62 1 16 1 1 1 1 0 0 1 0.32 0.06 136 D 0 -1 1 5 -3 0 1 1 -1 -3 -3 0 -2 -3 -1 0 -1 -3 -3 -2 12 1 5 52 0 0 6 11 0 1 1 7 0 0 1 1 1 0 0 1 0.47 0.05 137 G 1 -1 2 -1 -2 -1 -1 4 -1 -2 -2 -1 -2 -2 -1 1 0 -2 -2 -2 12 1 12 1 0 1 1 46 0 1 2 1 0 1 1 11 7 0 1 1 0.40 0.03 138 P 0 -2 -1 -1 -2 -1 -1 -1 -2 -1 0 -1 -1 -2 5 2 0 -3 -2 0 5 1 1 1 0 1 1 1 0 1 11 1 0 1 36 29 1 0 1 7 0.53 0.04 139 A 3 -1 -1 -1 -1 -1 -1 -1 -2 -2 -2 -1 -1 -2 3 2 1 -2 -2 -1 44 1 1 1 0 1 1 1 0 1 1 1 0 1 13 19 12 0 1 1 0.32 0.04 140 G 0 0 -1 -1 -2 -1 -2 5 -2 -3 -3 -1 -2 -3 -2 1 0 -3 -3 -3 1 7 1 1 0 0 1 69 0 1 1 1 0 0 1 9 6 0 0 1 0.68 0.06 141 A 1 -1 0 5 -3 0 3 -1 -1 -3 -3 0 -2 -3 -1 0 -1 -3 -2 -2 17 1 1 47 0 0 27 1 0 1 1 1 0 0 1 1 1 0 0 1 0.52 0.05 142 L -2 -3 -4 -4 -2 -3 -3 -4 -3 2 4 -3 2 1 -3 -3 -1 -2 -1 2 0 0 0 0 0 0 0 0 0 6 79 0 0 4 0 0 0 0 0 11 0.53 0.07 143 L -2 -3 -4 -4 -2 -3 -4 -4 -3 2 5 -3 2 0 -3 -3 -2 -2 -2 1 0 0 0 0 0 0 0 0 0 11 89 0 0 0 0 0 0 0 0 0 0.63 0.08 144 L -2 2 -3 -3 -2 0 -2 -4 -2 1 4 -1 2 0 -3 -2 -2 -2 -2 0 0 16 0 0 0 5 0 0 0 0 73 0 6 0 0 0 0 0 0 0 0.40 0.07 145 R -2 5 -1 -2 -4 0 0 -3 -1 -2 -3 3 -2 -3 -2 -1 -2 3 -2 -3 0 64 0 0 0 0 0 0 0 4 0 26 0 0 0 0 0 5 0 0 0.72 0.09 146 L -2 -3 -4 -4 -2 -3 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -2 1 0 0 0 0 0 0 0 0 0 0 83 0 5 0 0 0 0 0 0 12 0.57 0.08 147 V -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 4 0 -3 -3 -1 -2 -2 2 0 0 0 0 0 0 0 0 0 0 59 0 24 0 0 0 0 0 0 17 0.48 0.07 148 Q -2 1 2 -1 -3 3 0 -2 7 -3 0 0 -1 -2 -3 -1 -2 -3 0 -3 0 6 12 0 0 24 0 0 46 0 12 0 0 0 0 0 0 0 0 0 0.56 0.08 149 L -2 -2 -4 -4 -2 -2 -3 -4 -3 1 4 -3 4 1 -3 -3 -2 -2 -1 0 0 0 0 0 0 0 0 0 0 0 70 0 24 6 0 0 0 0 0 0 0.51 0.06 150 A 5 -2 -2 -2 -1 -1 -1 0 -2 0 -2 -1 -1 -3 -1 1 0 -3 -2 0 86 0 0 0 0 0 0 0 0 8 0 0 0 0 0 7 0 0 0 0 0.48 0.07 151 G 0 -2 3 1 -3 -1 -1 4 -1 -4 -4 -1 -3 -3 -2 1 -1 -3 -3 -3 6 0 26 10 0 0 0 46 0 0 0 0 0 0 0 11 0 0 0 0 0.53 0.03 152 A 2 1 -1 -2 -1 0 -1 -1 4 -1 0 -1 -1 -2 -2 0 1 -3 -1 -1 42 10 0 0 0 0 0 0 24 0 11 0 0 0 0 0 13 0 0 0 0.20 0.02 153 P -1 1 -1 -1 -2 2 0 -2 -1 -2 -2 0 -1 -3 5 0 3 -3 -2 -1 0 8 0 0 0 20 0 0 0 0 0 0 0 0 30 0 42 0 0 0 0.55 0.02 154 E -1 -1 -1 0 -3 2 4 -2 -1 -3 -3 0 -2 -4 4 1 -1 -3 -2 -3 0 0 0 0 0 13 46 0 0 0 0 0 0 0 29 13 0 0 0 0 0.66 0.02 155 P 0 -2 -1 -1 -3 -1 -1 1 -2 -3 -3 -1 -3 -4 7 1 -1 -4 -3 -3 0 0 0 0 0 0 0 13 0 0 0 0 0 0 71 16 0 0 0 0 1.36 0.03 156 F 0 1 -1 -2 -2 0 -1 -2 6 -1 -1 -1 -1 1 -2 -1 -1 -2 1 0 15 13 0 0 0 0 0 1 42 0 1 0 0 8 0 1 0 0 0 17 0.25 0.02 157 E -1 2 0 3 -4 4 3 -2 0 -3 -3 1 -1 -3 -2 0 -1 -3 -2 -3 0 17 0 18 0 40 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0.50 0.01 158 P 0 -2 -2 -2 -2 -1 -1 -2 -2 0 -2 -1 -1 -3 6 1 0 -4 -2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56 21 0 0 0 24 0.90 0.01 159 A 3 -1 -1 -2 -1 0 -1 0 5 -2 -2 -1 -1 -2 -1 1 0 -3 0 -1 72 0 0 0 0 0 0 0 28 0 0 0 0 0 0 0 0 0 0 0 0.34 0.01 160 Q 0 1 0 -1 -3 5 1 -2 0 -3 -2 3 -1 -3 -1 0 -1 -2 -2 -2 13 0 0 0 0 63 0 0 0 0 0 24 0 0 0 0 0 0 0 0 0.46 0.01 161 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.04 0.00 162 D -1 3 0 2 -3 0 -1 4 -1 -4 -3 0 -2 -3 -2 0 -1 -3 -3 -3 0 34 0 16 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0.49 0.00 163 A 1 -2 -2 -3 -1 -2 -2 1 -3 2 0 -2 0 -1 -2 -1 0 -3 -2 3 16 0 0 0 0 0 0 18 0 0 0 0 0 0 0 0 0 0 0 66 0.19 0.00 164 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -1 -1 -2 -1 3 -3 -2 -2 2 7 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.86 0.00 K Lambda Standard Ungapped 0.1396 0.3230 Standard Gapped 0.0410 0.2670 PSI Ungapped 0.1396 0.3230 PSI Gapped 0.0410 0.2670