BLASTP 2.11.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: unitmol_20240501.fasta
           835,512 sequences; 240,313,072 total letters



Query= sp|Q96JC1|VPS39_HUMAN Vam6/Vps39-like protein OS=Homo sapiens
OX=9606 GN=VPS39 PE=1 SV=2

Length=886
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

6ze9_A A Vam6/Vps39-like protein                                      85.1    3e-19
6ze9_B B Vam6/Vps39-like protein                                      85.1    3e-19
6ze9_C C Vam6/Vps39-like protein                                      71.2    3e-14
7zty_A A CNH domain-containing protein                                65.9    1e-09
5o51_A A Rho guanyl nucleotide exchange factor (Rom2), putative       43.9    0.006


>6ze9_A A Vam6/Vps39-like protein
Length=44

 Score = 85.1 bits (209),  Expect = 3e-19, Method: Composition-based stats.
 Identities = 36/36 (100%), Positives = 36/36 (100%), Gaps = 0/36 (0%)

Query  851  VCMVCKKKIGNSAFARYPNGVVVHYFCSKEVNPADT  886
            VCMVCKKKIGNSAFARYPNGVVVHYFCSKEVNPADT
Sbjct  9    VCMVCKKKIGNSAFARYPNGVVVHYFCSKEVNPADT  44


>6ze9_B B Vam6/Vps39-like protein
Length=44

 Score = 85.1 bits (209),  Expect = 3e-19, Method: Composition-based stats.
 Identities = 36/36 (100%), Positives = 36/36 (100%), Gaps = 0/36 (0%)

Query  851  VCMVCKKKIGNSAFARYPNGVVVHYFCSKEVNPADT  886
            VCMVCKKKIGNSAFARYPNGVVVHYFCSKEVNPADT
Sbjct  9    VCMVCKKKIGNSAFARYPNGVVVHYFCSKEVNPADT  44


>6ze9_C C Vam6/Vps39-like protein
Length=44

 Score = 71.2 bits (173),  Expect = 3e-14, Method: Composition-based stats.
 Identities = 30/30 (100%), Positives = 30/30 (100%), Gaps = 0/30 (0%)

Query  851  VCMVCKKKIGNSAFARYPNGVVVHYFCSKE  880
            VCMVCKKKIGNSAFARYPNGVVVHYFCSKE
Sbjct  9    VCMVCKKKIGNSAFARYPNGVVVHYFCSKE  38


>7zty_A A CNH domain-containing protein
Length=542

 Score = 65.9 bits (159),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 64/307 (21%), Positives = 135/307 (44%), Gaps = 45/307 (15%)

Query  75   KKIQQIHVVSQFKILVSLLENNIYVHDLLTFQQITT-VSKAKGASLFTCD---LQHTETG  130
            + I+Q+ ++ +   LVSL    + +HDL TF+ I + + + K AS F      ++   TG
Sbjct  111  RAIEQLAIIKEANTLVSLSNYCVSLHDLHTFEPIASPLPRTKNASGFAVTSNIVKDPATG  170

Query  131  --EEVLRMCVAVKKKLQLYFWKDREFHELQGDFSVPDVPKSMAW-CENSICVGFKRDYYL  187
              E + R+ V+VK++L L+ W + E  E   +  + +  +SM W C   +  G    + +
Sbjct  171  IPEIISRLAVSVKRRLLLWSWHESELEEEVKEVVLTESIRSMTWACATRLVCGMNSGFVV  230

Query  188  IRVDGKGSIKELFPTGKQL--------------------------EPLVAPLADGKVAVG  221
            + V+  G+++++                                 +PL   LADG++ + 
Sbjct  231  VDVE-TGTVEDILGXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMPKPLCTKLADGQLLLA  289

Query  222  QDDLTVVLNEEGICTQKCALNWTDIPVAMEHQPPYIIAVLPRY---VEIRTFEPRLL---  275
            +D  T+ +++ G   +K  + W   P  + +  PYI+A+ P     +E+R  +   L   
Sbjct  290  KDVNTLFIDDTGKALEKRQIPWQAAPDGIGYSYPYILALQPPAKGCLEVRNPDTLSLLQT  349

Query  276  -----VQSIELQRPRFITSGGSNIIYVASNHFVWRLIPVPMATQIQQLLQDKQFELALQL  330
                   ++                +V S+  VW++      +Q+++L++  + + A+ +
Sbjct  350  LSLPGAAALHFPXXXXXXXXXGKGFHVLSDRVVWKMDATDYDSQVEELVRGGKLDEAISV  409

Query  331  AEMKDDS  337
              M +D+
Sbjct  410  LTMLEDA  416


>5o51_A A Rho guanyl nucleotide exchange factor (Rom2), putative
Length=338

 Score = 43.9 bits (102),  Expect = 0.006, Method: Compositional matrix adjust.
 Identities = 29/148 (20%), Positives = 63/148 (43%), Gaps = 10/148 (7%)

Query  160  DFSVPDVPKSMAWCENSICVGFKRDYYLIRV---------DGKGSIKELFPTGKQLEPLV  210
            ++ +P    S+ +  +++CVG  R + ++ +         D   +  +     + ++P+ 
Sbjct  173  EYYIPAESSSIHFLRSTLCVGCARGFEVVSLETTETQSLLDQADTSLDFVARKENVKPIH  232

Query  211  APLADGKVAVGQDDLTVVLNEEGICTQ-KCALNWTDIPVAMEHQPPYIIAVLPRYVEIRT  269
                +G+  +   D +  +N  G   +    ++W   P A     PYI+A  P ++EIR 
Sbjct  233  IERMNGEFLLNYSDFSFFVNRNGWRARPDWKISWEGNPNAFALSYPYILAFEPNFIEIRH  292

Query  270  FEPRLLVQSIELQRPRFITSGGSNIIYV  297
             E   L+  +  +  R + S    I+Y 
Sbjct  293  IETSELIHIMTGKNIRMLHSSTREILYA  320



Lambda      K        H        a         alpha
   0.321    0.138    0.410    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 101860113432


  Database: unitmol_20240501.fasta
    Posted date:  May 2, 2024  10:24 AM
  Number of letters in database: 240,313,072
  Number of sequences in database:  835,512



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40