[Multiple Alignment(many alignments)]
[Alignment Bar(many alignments)]
[show plain BLAST file]
BLASTP 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: unitmol_20240403.fasta
829,018 sequences; 237,935,689 total letters
Query= sp|P84022|SMAD3_HUMAN Mothers against decapentaplegic homolog 3
OS=Homo sapiens OX=9606 GN=SMAD3 PE=1 SV=1
Length=425
Score E
Sequences producing significant alignments: (Bits) Value
1mk2_A A SMAD 3 418 1e-146
6m64_A A Mothers against decapentaplegic homolog 2 416 9e-146
1khx_A A Smad2 416 3e-145
1u7f_A A Mothers against decapentaplegic homolog 3 415 3e-145
6zvq_A A Mothers against decapentaplegic homolog 2 414 2e-144
5xoc_A A Mothers against decapentaplegic homolog 3 411 4e-144
1u7f_C C Mothers against decapentaplegic homolog 3 410 1e-143
1u7v_A A Mothers against decapentaplegic homolog 2 408 1e-142
1dev_A A MAD (mothers against decapentaplegic, Drosophila) homolog 2 404 3e-141
1u7v_B C Mothers against decapentaplegic homolog 2 404 4e-141
7co1_A A Mothers against decapentaplegic homolog 2 404 4e-141
6m64_C C Mothers against decapentaplegic homolog 2 404 6e-141
7co1_C C Mothers against decapentaplegic homolog 2 402 3e-140
6m64_E E Mothers against decapentaplegic homolog 2 402 3e-140
7co1_E E Mothers against decapentaplegic homolog 2 400 1e-139
1dev_C C MAD (mothers against decapentaplegic, Drosophila) homolog 2 398 6e-139
5xod_A A Mothers against decapentaplegic homolog 2 393 8e-137
5zoj_A A Mothers against decapentaplegic homolog 2 392 1e-136
5zoj_C C Mothers against decapentaplegic homolog 2 390 8e-136
5zoj_B B Mothers against decapentaplegic homolog 2 389 4e-135
1mjs_A A SMAD 3 369 1e-127
1khu_A A SMAD1 331 3e-112
5zok_C C Mothers against decapentaplegic homolog 1 331 3e-112
5zok_A A Mothers against decapentaplegic homolog 1 331 3e-112
1khu_C C SMAD1 330 1e-111
1khu_B B SMAD1 330 1e-111
3gmj_C A Protein mothers against dpp 327 3e-110
3gmj_B B Protein mothers against dpp 327 3e-110
3gmj_A D Protein mothers against dpp 327 3e-110
1khu_D D SMAD1 319 2e-107
3dit_C C Protein mothers against dpp 316 7e-107
3gmj_D C Protein mothers against dpp 317 3e-106
3dit_B B Protein mothers against dpp 315 4e-106
3dit_A A Protein mothers against dpp 313 2e-105
1ozj_C A SMAD 3 267 4e-88
5odg_A A Mothers against decapentaplegic homolog 3 264 4e-87
5od6_B B Mothers against decapentaplegic homolog 3 264 4e-87
5odg_B B Mothers against decapentaplegic homolog 3 262 2e-86
5od6_A A Mothers against decapentaplegic homolog 3 262 2e-86
1ozj_D B SMAD 3 262 3e-86
1mhd_D B SMAD3 260 1e-85
1mhd_C A SMAD3 260 1e-85
6zmn_A A Mothers against decapentaplegic homolog 3 221 2e-70
6zmn_B B Mothers against decapentaplegic homolog 3 217 6e-69
6h3r_A A Mothers against decapentaplegic homolog 206 2e-64
6h3r_B B Mothers against decapentaplegic homolog 206 2e-64
6tbz_A A Mothers against decapentaplegic homolog 5 191 9e-59
6fzs_B B Mothers against decapentaplegic homolog 5 182 3e-55
6fzt_B B Mothers against decapentaplegic homolog 9 182 6e-55
6fzs_A A Mothers against decapentaplegic homolog 5 179 4e-54
6fzt_A A Mothers against decapentaplegic homolog 9 177 3e-53
5x6m_A B Mothers against decapentaplegic homolog 5 175 4e-52
6tce_A A Mothers against decapentaplegic homolog 5 174 6e-52
5x6g_B B Mothers against decapentaplegic homolog 5 174 7e-52
3kmp_A A SMAD1-MH1 173 1e-51
5x6g_A A Mothers against decapentaplegic homolog 5 173 2e-51
5x6m_D A Mothers against decapentaplegic homolog 5 172 3e-51
5x6m_E E Mothers against decapentaplegic homolog 5 172 4e-51
5x6m_H F Mothers against decapentaplegic homolog 5 172 4e-51
3kmp_B B SMAD1-MH1 170 8e-51
1dd1_C C SMAD4 166 4e-47
1dd1_B B SMAD4 166 4e-47
1g88_C C SMAD4 163 3e-46
1g88_B B SMAD4 163 4e-46
1u7v_C B Mothers against decapentaplegic homolog 4 161 6e-46
5x6h_A B Mothers against decapentaplegic homolog 5 158 7e-46
1mr1_B B Mothers against decapentaplegic homolog 4 161 8e-46
1ygs_A A SMAD4 161 1e-45
1mr1_A A Mothers against decapentaplegic homolog 4 161 1e-45
1dd1_A A SMAD4 161 2e-45
5c4v_A A Mothers against decapentaplegic homolog 4 160 4e-45
5c4v_C E Mothers against decapentaplegic homolog 4 160 5e-45
5c4v_B C Mothers against decapentaplegic homolog 4 159 6e-45
1g88_A A SMAD4 159 2e-44
1u7f_B B Mothers against decapentaplegic homolog 4 155 2e-43
5nm9_A A Mothers against decapentaplegic homolog 136 2e-37
5nm9_B B Mothers against decapentaplegic homolog 135 3e-37
5mez_A A MH1 domain of human Smad4 121 8e-32
3qsv_B B Mothers against decapentaplegic homolog 4 119 4e-31
3qsv_A A Mothers against decapentaplegic homolog 4 119 4e-31
3qsv_D D Mothers against decapentaplegic homolog 4 119 6e-31
5mey_A A MH1 domain of human Smad4 119 6e-31
5mf0_B B MH1 domain of human Smad4 119 6e-31
3qsv_C C Mothers against decapentaplegic homolog 4 118 7e-31
5mf0_A A MH1 domain of human Smad4 118 7e-31
5mez_B B MH1 domain of human Smad4 118 8e-31
7cd1_D D Mothers against decapentaplegic homolog 7 85.9 2e-18
7cd1_C C Mothers against decapentaplegic homolog 7 85.9 2e-18
7cd1_B B Mothers against decapentaplegic homolog 7 85.9 2e-18
7cd1_A A Mothers against decapentaplegic homolog 7 85.9 2e-18
4r9p_A A RE28239p 50.8 7e-06
>1mk2_A A SMAD 3
Length=206
Score = 418 bits (1075), Expect = 1e-146, Method: Compositional matrix adjust.
Identities = 197/197 (100%), Positives = 197/197 (100%), Gaps = 0/197 (0%)
Query 220 DLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNR 279
DLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNR
Sbjct 1 DLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNR 60
Query 280 NAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCN 339
NAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCN
Sbjct 61 NAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCN 120
Query 340 LKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELH 399
LKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELH
Sbjct 121 LKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELH 180
Query 400 LNGPLQWLDKVLTQMGS 416
LNGPLQWLDKVLTQMGS
Sbjct 181 LNGPLQWLDKVLTQMGS 197
>6m64_A A Mothers against decapentaplegic homolog 2
Length=208
Score = 416 bits (1069), Expect = 9e-146, Method: Compositional matrix adjust.
Identities = 194/202 (96%), Positives = 199/202 (99%), Gaps = 0/202 (0%)
Query 223 PVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAA 282
PVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA
Sbjct 6 PVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNAT 65
Query 283 VELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKI 342
VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKI
Sbjct 66 VEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKI 125
Query 343 FNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNG 402
FNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNG
Sbjct 126 FNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNG 185
Query 403 PLQWLDKVLTQMGSPSIRCSSV 424
PLQWLDKVLTQMGSPS+RCS +
Sbjct 186 PLQWLDKVLTQMGSPSVRCSEM 207
>1khx_A A Smad2
Length=235
Score = 416 bits (1069), Expect = 3e-145, Method: Compositional matrix adjust.
Identities = 194/202 (96%), Positives = 199/202 (99%), Gaps = 0/202 (0%)
Query 223 PVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAA 282
PVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA
Sbjct 25 PVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNAT 84
Query 283 VELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKI 342
VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKI
Sbjct 85 VEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKI 144
Query 343 FNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNG 402
FNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNG
Sbjct 145 FNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNG 204
Query 403 PLQWLDKVLTQMGSPSIRCSSV 424
PLQWLDKVLTQMGSPS+RCS +
Sbjct 205 PLQWLDKVLTQMGSPSVRCSXM 226
>1u7f_A A Mothers against decapentaplegic homolog 3
Length=206
Score = 415 bits (1066), Expect = 3e-145, Method: Compositional matrix adjust.
Identities = 196/197 (99%), Positives = 196/197 (99%), Gaps = 0/197 (0%)
Query 228 EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTR 287
EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTR
Sbjct 1 EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTR 60
Query 288 RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE 347
RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE
Sbjct 61 RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE 120
Query 348 FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWL 407
FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWL
Sbjct 121 FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWL 180
Query 408 DKVLTQMGSPSIRCSSV 424
DKVLTQMGSPSIRCS V
Sbjct 181 DKVLTQMGSPSIRCSXV 197
>6zvq_A A Mothers against decapentaplegic homolog 2
Length=235
Score = 414 bits (1063), Expect = 2e-144, Method: Compositional matrix adjust.
Identities = 193/201 (96%), Positives = 198/201 (99%), Gaps = 0/201 (0%)
Query 224 VTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAV 283
VTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA V
Sbjct 26 VTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATV 85
Query 284 ELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 343
E+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF
Sbjct 86 EMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 145
Query 344 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 403
NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP
Sbjct 146 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 205
Query 404 LQWLDKVLTQMGSPSIRCSSV 424
LQWLDKVLTQMGSPS+RCS +
Sbjct 206 LQWLDKVLTQMGSPSVRCSXM 226
>5xoc_A A Mothers against decapentaplegic homolog 3
Length=199
Score = 411 bits (1057), Expect = 4e-144, Method: Compositional matrix adjust.
Identities = 194/194 (100%), Positives = 194/194 (100%), Gaps = 0/194 (0%)
Query 221 LQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRN 280
LQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRN
Sbjct 4 LQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRN 63
Query 281 AAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNL 340
AAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNL
Sbjct 64 AAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNL 123
Query 341 KIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHL 400
KIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHL
Sbjct 124 KIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHL 183
Query 401 NGPLQWLDKVLTQM 414
NGPLQWLDKVLTQM
Sbjct 184 NGPLQWLDKVLTQM 197
>1u7f_C C Mothers against decapentaplegic homolog 3
Length=206
Score = 410 bits (1055), Expect = 1e-143, Method: Compositional matrix adjust.
Identities = 194/195 (99%), Positives = 194/195 (99%), Gaps = 0/195 (0%)
Query 230 AFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRH 289
AFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRH
Sbjct 3 AFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRH 62
Query 290 IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA 349
IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA
Sbjct 63 IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA 122
Query 350 ALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDK 409
ALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDK
Sbjct 123 ALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDK 182
Query 410 VLTQMGSPSIRCSSV 424
VLTQMGSPSIRCS V
Sbjct 183 VLTQMGSPSIRCSXV 197
>1u7v_A A Mothers against decapentaplegic homolog 2
Length=206
Score = 408 bits (1049), Expect = 1e-142, Method: Compositional matrix adjust.
Identities = 190/197 (96%), Positives = 195/197 (99%), Gaps = 0/197 (0%)
Query 228 EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTR 287
EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA VE+TR
Sbjct 1 EPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTR 60
Query 288 RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE 347
RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE
Sbjct 61 RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE 120
Query 348 FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWL 407
FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWL
Sbjct 121 FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWL 180
Query 408 DKVLTQMGSPSIRCSSV 424
DKVLTQMGSPS+RCS +
Sbjct 181 DKVLTQMGSPSVRCSXM 197
>1dev_A A MAD (mothers against decapentaplegic, Drosophila) homolog
2
Length=196
Score = 404 bits (1038), Expect = 3e-141, Method: Compositional matrix adjust.
Identities = 189/194 (97%), Positives = 192/194 (99%), Gaps = 0/194 (0%)
Query 221 LQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRN 280
LQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRN
Sbjct 3 LQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRN 62
Query 281 AAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNL 340
A VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNL
Sbjct 63 ATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNL 122
Query 341 KIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHL 400
KIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHL
Sbjct 123 KIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHL 182
Query 401 NGPLQWLDKVLTQM 414
NGPLQWLDKVLTQM
Sbjct 183 NGPLQWLDKVLTQM 196
>1u7v_B C Mothers against decapentaplegic homolog 2
Length=206
Score = 404 bits (1038), Expect = 4e-141, Method: Compositional matrix adjust.
Identities = 188/195 (96%), Positives = 193/195 (99%), Gaps = 0/195 (0%)
Query 230 AFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRH 289
AFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRRH
Sbjct 3 AFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRH 62
Query 290 IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA 349
IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA
Sbjct 63 IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA 122
Query 350 ALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDK 409
ALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDK
Sbjct 123 ALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDK 182
Query 410 VLTQMGSPSIRCSSV 424
VLTQMGSPS+RCS +
Sbjct 183 VLTQMGSPSVRCSXM 197
>7co1_A A Mothers against decapentaplegic homolog 2
Length=208
Score = 404 bits (1038), Expect = 4e-141, Method: Compositional matrix adjust.
Identities = 189/194 (97%), Positives = 192/194 (99%), Gaps = 0/194 (0%)
Query 223 PVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAA 282
PVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA
Sbjct 6 PVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNAT 65
Query 283 VELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKI 342
VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKI
Sbjct 66 VEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKI 125
Query 343 FNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNG 402
FNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNG
Sbjct 126 FNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNG 185
Query 403 PLQWLDKVLTQMGS 416
PLQWLDKVLTQMGS
Sbjct 186 PLQWLDKVLTQMGS 199
>6m64_C C Mothers against decapentaplegic homolog 2
Length=208
Score = 404 bits (1037), Expect = 6e-141, Method: Compositional matrix adjust.
Identities = 189/194 (97%), Positives = 192/194 (99%), Gaps = 0/194 (0%)
Query 225 TYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVE 284
TY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA VE
Sbjct 8 TYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVE 67
Query 285 LTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFN 344
+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFN
Sbjct 68 MTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFN 127
Query 345 NQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPL 404
NQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPL
Sbjct 128 NQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPL 187
Query 405 QWLDKVLTQMGSPS 418
QWLDKVLTQMGSPS
Sbjct 188 QWLDKVLTQMGSPS 201
>7co1_C C Mothers against decapentaplegic homolog 2
Length=208
Score = 402 bits (1033), Expect = 3e-140, Method: Compositional matrix adjust.
Identities = 188/193 (97%), Positives = 191/193 (99%), Gaps = 0/193 (0%)
Query 224 VTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAV 283
VTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA V
Sbjct 7 VTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATV 66
Query 284 ELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 343
E+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF
Sbjct 67 EMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 126
Query 344 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 403
NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP
Sbjct 127 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 186
Query 404 LQWLDKVLTQMGS 416
LQWLDKVLTQMGS
Sbjct 187 LQWLDKVLTQMGS 199
>6m64_E E Mothers against decapentaplegic homolog 2
Length=208
Score = 402 bits (1033), Expect = 3e-140, Method: Compositional matrix adjust.
Identities = 188/193 (97%), Positives = 191/193 (99%), Gaps = 0/193 (0%)
Query 224 VTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAV 283
VTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA V
Sbjct 7 VTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATV 66
Query 284 ELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 343
E+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF
Sbjct 67 EMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 126
Query 344 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 403
NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP
Sbjct 127 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 186
Query 404 LQWLDKVLTQMGS 416
LQWLDKVLTQMGS
Sbjct 187 LQWLDKVLTQMGS 199
>7co1_E E Mothers against decapentaplegic homolog 2
Length=208
Score = 400 bits (1028), Expect = 1e-139, Method: Compositional matrix adjust.
Identities = 187/192 (97%), Positives = 190/192 (99%), Gaps = 0/192 (0%)
Query 224 VTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAV 283
VTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA V
Sbjct 7 VTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATV 66
Query 284 ELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 343
E+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF
Sbjct 67 EMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIF 126
Query 344 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 403
NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP
Sbjct 127 NNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 186
Query 404 LQWLDKVLTQMG 415
LQWLDKVLTQMG
Sbjct 187 LQWLDKVLTQMG 198
>1dev_C C MAD (mothers against decapentaplegic, Drosophila) homolog
2
Length=196
Score = 398 bits (1023), Expect = 6e-139, Method: Compositional matrix adjust.
Identities = 187/196 (95%), Positives = 190/196 (97%), Gaps = 0/196 (0%)
Query 219 LDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVN 278
LDLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVN
Sbjct 1 LDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVN 60
Query 279 RNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGC 338
RNA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGC
Sbjct 61 RNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGC 120
Query 339 NLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIEL 398
NLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWG RQTVTSTPCWIEL
Sbjct 121 NLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGXXXXRQTVTSTPCWIEL 180
Query 399 HLNGPLQWLDKVLTQM 414
HLNGPLQWLDKVLTQM
Sbjct 181 HLNGPLQWLDKVLTQM 196
>5xod_A A Mothers against decapentaplegic homolog 2
Length=199
Score = 393 bits (1009), Expect = 8e-137, Method: Compositional matrix adjust.
Identities = 186/195 (95%), Positives = 189/195 (97%), Gaps = 0/195 (0%)
Query 220 DLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNR 279
DLQPVTY EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNR
Sbjct 3 DLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNR 62
Query 280 NAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCN 339
NA VE+TRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQR PATVCKIPPGCN
Sbjct 63 NATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRXXXXPATVCKIPPGCN 122
Query 340 LKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELH 399
LKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELH
Sbjct 123 LKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELH 182
Query 400 LNGPLQWLDKVLTQM 414
LNGPLQWLDKVLTQM
Sbjct 183 LNGPLQWLDKVLTQM 197
>5zoj_A A Mothers against decapentaplegic homolog 2
Length=200
Score = 392 bits (1008), Expect = 1e-136, Method: Compositional matrix adjust.
Identities = 183/187 (98%), Positives = 186/187 (99%), Gaps = 0/187 (0%)
Query 228 EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTR 287
EPAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA VE+TR
Sbjct 12 EPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTR 71
Query 288 RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE 347
RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE
Sbjct 72 RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE 131
Query 348 FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWL 407
FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWL
Sbjct 132 FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWL 191
Query 408 DKVLTQM 414
DKVLTQM
Sbjct 192 DKVLTQM 198
>5zoj_C C Mothers against decapentaplegic homolog 2
Length=200
Score = 390 bits (1003), Expect = 8e-136, Method: Compositional matrix adjust.
Identities = 182/186 (98%), Positives = 185/186 (99%), Gaps = 0/186 (0%)
Query 229 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR 288
PAFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRR
Sbjct 13 PAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRR 72
Query 289 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 348
HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF
Sbjct 73 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 132
Query 349 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 408
AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD
Sbjct 133 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 192
Query 409 KVLTQM 414
KVLTQM
Sbjct 193 KVLTQM 198
>5zoj_B B Mothers against decapentaplegic homolog 2
Length=200
Score = 389 bits (998), Expect = 4e-135, Method: Compositional matrix adjust.
Identities = 181/185 (98%), Positives = 184/185 (99%), Gaps = 0/185 (0%)
Query 230 AFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRH 289
AFWCSI+YYELNQRVGETFHASQPS+TVDGFTDPSNSERFCLGLLSNVNRNA VE+TRRH
Sbjct 14 AFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRH 73
Query 290 IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA 349
IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA
Sbjct 74 IGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA 133
Query 350 ALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDK 409
ALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDK
Sbjct 134 ALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDK 193
Query 410 VLTQM 414
VLTQM
Sbjct 194 VLTQM 198
>1mjs_A A SMAD 3
Length=197
Score = 369 bits (948), Expect = 1e-127, Method: Compositional matrix adjust.
Identities = 178/190 (94%), Positives = 178/190 (94%), Gaps = 0/190 (0%)
Query 229 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR 288
PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR
Sbjct 1 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRR 60
Query 289 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 348
HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQR ATVCKIPPGCNLKIFNNQEF
Sbjct 61 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRXXXXXATVCKIPPGCNLKIFNNQEF 120
Query 349 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 408
AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGW TVTSTPCWIELHLNGPLQWLD
Sbjct 121 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWXXXXXXXTVTSTPCWIELHLNGPLQWLD 180
Query 409 KVLTQMGSPS 418
KVLTQMGSPS
Sbjct 181 KVLTQMGSPS 190
>1khu_A A SMAD1
Length=218
Score = 331 bits (849), Expect = 3e-112, Method: Compositional matrix adjust.
Identities = 156/198 (79%), Positives = 172/198 (87%), Gaps = 1/198 (1%)
Query 229 PAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTR 287
P WCSI YYELN RVGE FHAS S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E TR
Sbjct 21 PKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTR 80
Query 288 RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE 347
RHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN +G+HP TVCKIP GC+LKIFNNQE
Sbjct 81 RHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQE 140
Query 348 FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWL 407
FA LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWL
Sbjct 141 FAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWL 200
Query 408 DKVLTQMGSPSIRCSSVS 425
DKVLTQMGSP SSVS
Sbjct 201 DKVLTQMGSPHNPISSVS 218
>5zok_C C Mothers against decapentaplegic homolog 1
Length=209
Score = 331 bits (848), Expect = 3e-112, Method: Compositional matrix adjust.
Identities = 153/191 (80%), Positives = 169/191 (88%), Gaps = 1/191 (1%)
Query 228 EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELT 286
EP WCSI YYELN RVGE FHAS S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E T
Sbjct 11 EPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENT 70
Query 287 RRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQ 346
RRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN +G+HP TVCKIP GC+LKIFNNQ
Sbjct 71 RRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQ 130
Query 347 EFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQW 406
EFA LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQW
Sbjct 131 EFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQW 190
Query 407 LDKVLTQMGSP 417
LDKVLTQMGSP
Sbjct 191 LDKVLTQMGSP 201
>5zok_A A Mothers against decapentaplegic homolog 1
Length=209
Score = 331 bits (848), Expect = 3e-112, Method: Compositional matrix adjust.
Identities = 153/191 (80%), Positives = 169/191 (88%), Gaps = 1/191 (1%)
Query 228 EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELT 286
EP WCSI YYELN RVGE FHAS S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E T
Sbjct 11 EPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENT 70
Query 287 RRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQ 346
RRHIG+GV LYY+GGEV+AECLSDS+IFVQS NCN +G+HP TVCKIP GC+LKIFNNQ
Sbjct 71 RRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQ 130
Query 347 EFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQW 406
EFA LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQW
Sbjct 131 EFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQW 190
Query 407 LDKVLTQMGSP 417
LDKVLTQMGSP
Sbjct 191 LDKVLTQMGSP 201
>1khu_C C SMAD1
Length=218
Score = 330 bits (845), Expect = 1e-111, Method: Compositional matrix adjust.
Identities = 155/195 (79%), Positives = 171/195 (88%), Gaps = 1/195 (1%)
Query 232 WCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHI 290
WCSI YYELN RVGE FHAS S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHI
Sbjct 24 WCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHI 83
Query 291 GRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAA 350
G+GV LYY+GGEV+AECLSDS+IFVQS NCN +G+HP TVCKIP GC+LKIFNNQEFA
Sbjct 84 GKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQ 143
Query 351 LLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKV 410
LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKV
Sbjct 144 LLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKV 203
Query 411 LTQMGSPSIRCSSVS 425
LTQMGSP SSVS
Sbjct 204 LTQMGSPHNPISSVS 218
>1khu_B B SMAD1
Length=218
Score = 330 bits (845), Expect = 1e-111, Method: Compositional matrix adjust.
Identities = 155/195 (79%), Positives = 171/195 (88%), Gaps = 1/195 (1%)
Query 232 WCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHI 290
WCSI YYELN RVGE FHAS S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHI
Sbjct 24 WCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHI 83
Query 291 GRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAA 350
G+GV LYY+GGEV+AECLSDS+IFVQS NCN +G+HP TVCKIP GC+LKIFNNQEFA
Sbjct 84 GKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQ 143
Query 351 LLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKV 410
LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKV
Sbjct 144 LLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKV 203
Query 411 LTQMGSPSIRCSSVS 425
LTQMGSP SSVS
Sbjct 204 LTQMGSPHNPISSVS 218
>3gmj_C A Protein mothers against dpp
Length=245
Score = 327 bits (838), Expect = 3e-110, Method: Compositional matrix adjust.
Identities = 155/199 (78%), Positives = 175/199 (88%), Gaps = 1/199 (1%)
Query 228 EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSN-SERFCLGLLSNVNRNAAVELT 286
EPAFW SI+YYELN RVGE FH + S+ VDGFT+PSN S+R CLG LSNVNRN+ +E T
Sbjct 47 EPAFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNPSNNSDRCCLGQLSNVNRNSTIENT 106
Query 287 RRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQ 346
RRHIG+GV LYY+ GEV+AECLSDSAIFVQS NCN ++G+HP+TVCKIPPGC+LKIFNNQ
Sbjct 107 RRHIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYQHGFHPSTVCKIPPGCSLKIFNNQ 166
Query 347 EFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQW 406
EFA LL+QSVN GFEAVY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQW
Sbjct 167 EFAQLLSQSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQW 226
Query 407 LDKVLTQMGSPSIRCSSVS 425
LDKVLTQMGSP SSVS
Sbjct 227 LDKVLTQMGSPHNAISSVS 245
>3gmj_B B Protein mothers against dpp
Length=245
Score = 327 bits (838), Expect = 3e-110, Method: Compositional matrix adjust.
Identities = 155/199 (78%), Positives = 175/199 (88%), Gaps = 1/199 (1%)
Query 228 EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSN-SERFCLGLLSNVNRNAAVELT 286
EPAFW SI+YYELN RVGE FH + S+ VDGFT+PSN S+R CLG LSNVNRN+ +E T
Sbjct 47 EPAFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNPSNNSDRCCLGQLSNVNRNSTIENT 106
Query 287 RRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQ 346
RRHIG+GV LYY+ GEV+AECLSDSAIFVQS NCN ++G+HP+TVCKIPPGC+LKIFNNQ
Sbjct 107 RRHIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYQHGFHPSTVCKIPPGCSLKIFNNQ 166
Query 347 EFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQW 406
EFA LL+QSVN GFEAVY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQW
Sbjct 167 EFAQLLSQSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQW 226
Query 407 LDKVLTQMGSPSIRCSSVS 425
LDKVLTQMGSP SSVS
Sbjct 227 LDKVLTQMGSPHNAISSVS 245
>3gmj_A D Protein mothers against dpp
Length=245
Score = 327 bits (838), Expect = 3e-110, Method: Compositional matrix adjust.
Identities = 155/199 (78%), Positives = 175/199 (88%), Gaps = 1/199 (1%)
Query 228 EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSN-SERFCLGLLSNVNRNAAVELT 286
EPAFW SI+YYELN RVGE FH + S+ VDGFT+PSN S+R CLG LSNVNRN+ +E T
Sbjct 47 EPAFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNPSNNSDRCCLGQLSNVNRNSTIENT 106
Query 287 RRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQ 346
RRHIG+GV LYY+ GEV+AECLSDSAIFVQS NCN ++G+HP+TVCKIPPGC+LKIFNNQ
Sbjct 107 RRHIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYQHGFHPSTVCKIPPGCSLKIFNNQ 166
Query 347 EFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQW 406
EFA LL+QSVN GFEAVY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQW
Sbjct 167 EFAQLLSQSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQW 226
Query 407 LDKVLTQMGSPSIRCSSVS 425
LDKVLTQMGSP SSVS
Sbjct 227 LDKVLTQMGSPHNAISSVS 245
>1khu_D D SMAD1
Length=218
Score = 319 bits (817), Expect = 2e-107, Method: Compositional matrix adjust.
Identities = 147/183 (80%), Positives = 163/183 (89%), Gaps = 1/183 (1%)
Query 232 WCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHI 290
WCSI YYELN RVGE FHAS S+ VDGFTDPSN++ RFCLGLLSNVNRN+ +E TRRHI
Sbjct 24 WCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHI 83
Query 291 GRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAA 350
G+GV LYY+GGEV+AECLSDS+IFVQS NCN +G+HP TVCKIP GC+LKIFNNQEFA
Sbjct 84 GKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQ 143
Query 351 LLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKV 410
LLAQSVN GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKV
Sbjct 144 LLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKV 203
Query 411 LTQ 413
LTQ
Sbjct 204 LTQ 206
>3dit_C C Protein mothers against dpp
Length=188
Score = 316 bits (810), Expect = 7e-107, Method: Compositional matrix adjust.
Identities = 148/188 (79%), Positives = 167/188 (89%), Gaps = 1/188 (1%)
Query 230 AFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSN-SERFCLGLLSNVNRNAAVELTRR 288
AFW SI+YYELN RVGE FH + S+ VDGFT+PSN S+R CLG LSNVNRN+ +E TRR
Sbjct 1 AFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNPSNNSDRCCLGQLSNVNRNSTIENTRR 60
Query 289 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 348
HIG+GV LYY+ GEV+AECLSDSAIFVQS NCN +G+HP+TVCKIPPGC+LKIFNNQEF
Sbjct 61 HIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYHHGFHPSTVCKIPPGCSLKIFNNQEF 120
Query 349 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 408
A LL+QSVN GFEAVY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLD
Sbjct 121 AQLLSQSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLD 180
Query 409 KVLTQMGS 416
KVLTQMGS
Sbjct 181 KVLTQMGS 188
>3gmj_D C Protein mothers against dpp
Length=245
Score = 317 bits (812), Expect = 3e-106, Method: Compositional matrix adjust.
Identities = 148/188 (79%), Positives = 168/188 (89%), Gaps = 1/188 (1%)
Query 228 EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSN-SERFCLGLLSNVNRNAAVELT 286
EPAFW SI+YYELN RVGE FH + S+ VDGFT+PSN S+R CLG LSNVNRN+ +E T
Sbjct 47 EPAFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNPSNNSDRCCLGQLSNVNRNSTIENT 106
Query 287 RRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQ 346
RRHIG+GV LYY+ GEV+AECLSDSAIFVQS NCN ++G+HP+TVCKIPPGC+LKIFNNQ
Sbjct 107 RRHIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYQHGFHPSTVCKIPPGCSLKIFNNQ 166
Query 347 EFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQW 406
EFA LL+QSVN GFEAVY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQW
Sbjct 167 EFAQLLSQSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQW 226
Query 407 LDKVLTQM 414
LDKVLTQM
Sbjct 227 LDKVLTQM 234
>3dit_B B Protein mothers against dpp
Length=188
Score = 315 bits (806), Expect = 4e-106, Method: Compositional matrix adjust.
Identities = 147/188 (78%), Positives = 166/188 (88%), Gaps = 1/188 (1%)
Query 230 AFWCSISYYELNQRVGETFHASQPSMTVDGFTDPS-NSERFCLGLLSNVNRNAAVELTRR 288
AFW SI+YYELN RVGE FH + S+ VDGFT+P NS+R CLG LSNVNRN+ +E TRR
Sbjct 1 AFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNPXXNSDRCCLGQLSNVNRNSTIENTRR 60
Query 289 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 348
HIG+GV LYY+ GEV+AECLSDSAIFVQS NCN +G+HP+TVCKIPPGC+LKIFNNQEF
Sbjct 61 HIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYHHGFHPSTVCKIPPGCSLKIFNNQEF 120
Query 349 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 408
A LL+QSVN GFEAVY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLD
Sbjct 121 AQLLSQSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLD 180
Query 409 KVLTQMGS 416
KVLTQMGS
Sbjct 181 KVLTQMGS 188
>3dit_A A Protein mothers against dpp
Length=188
Score = 313 bits (801), Expect = 2e-105, Method: Compositional matrix adjust.
Identities = 146/188 (78%), Positives = 166/188 (88%), Gaps = 1/188 (1%)
Query 230 AFWCSISYYELNQRVGETFHASQPSMTVDGFTDP-SNSERFCLGLLSNVNRNAAVELTRR 288
AFW SI+YYELN RVGE FH + S+ VDGFT+ +NS+R CLG LSNVNRN+ +E TRR
Sbjct 1 AFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNXXNNSDRCCLGQLSNVNRNSTIENTRR 60
Query 289 HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF 348
HIG+GV LYY+ GEV+AECLSDSAIFVQS NCN +G+HP+TVCKIPPGC+LKIFNNQEF
Sbjct 61 HIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYHHGFHPSTVCKIPPGCSLKIFNNQEF 120
Query 349 AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD 408
A LL+QSVN GFEAVY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLD
Sbjct 121 AQLLSQSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLD 180
Query 409 KVLTQMGS 416
KVLTQMGS
Sbjct 181 KVLTQMGS 188
>1ozj_C A SMAD 3
Length=144
Score = 267 bits (682), Expect = 4e-88, Method: Compositional matrix adjust.
Identities = 126/126 (100%), Positives = 126/126 (100%), Gaps = 0/126 (0%)
Query 7 FTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCIT 66
FTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCIT
Sbjct 7 FTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCIT 66
Query 67 IPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYH 126
IPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYH
Sbjct 67 IPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYH 126
Query 127 YQRVET 132
YQRVET
Sbjct 127 YQRVET 132
>5odg_A A Mothers against decapentaplegic homolog 3
Length=128
Score = 264 bits (674), Expect = 4e-87, Method: Compositional matrix adjust.
Identities = 125/125 (100%), Positives = 125/125 (100%), Gaps = 0/125 (0%)
Query 11 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRS 70
IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRS
Sbjct 4 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRS 63
Query 71 LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV
Sbjct 64 LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 123
Query 131 ETPVL 135
ETPVL
Sbjct 124 ETPVL 128
>5od6_B B Mothers against decapentaplegic homolog 3
Length=128
Score = 264 bits (674), Expect = 4e-87, Method: Compositional matrix adjust.
Identities = 125/125 (100%), Positives = 125/125 (100%), Gaps = 0/125 (0%)
Query 11 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRS 70
IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRS
Sbjct 4 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRS 63
Query 71 LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV
Sbjct 64 LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 123
Query 131 ETPVL 135
ETPVL
Sbjct 124 ETPVL 128
>5odg_B B Mothers against decapentaplegic homolog 3
Length=128
Score = 262 bits (669), Expect = 2e-86, Method: Compositional matrix adjust.
Identities = 124/124 (100%), Positives = 124/124 (100%), Gaps = 0/124 (0%)
Query 11 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRS 70
IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRS
Sbjct 4 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRS 63
Query 71 LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV
Sbjct 64 LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 123
Query 131 ETPV 134
ETPV
Sbjct 124 ETPV 127
>5od6_A A Mothers against decapentaplegic homolog 3
Length=128
Score = 262 bits (669), Expect = 2e-86, Method: Compositional matrix adjust.
Identities = 124/124 (100%), Positives = 124/124 (100%), Gaps = 0/124 (0%)
Query 11 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRS 70
IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRS
Sbjct 4 IVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPRS 63
Query 71 LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV
Sbjct 64 LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 123
Query 131 ETPV 134
ETPV
Sbjct 124 ETPV 127
>1ozj_D B SMAD 3
Length=144
Score = 262 bits (669), Expect = 3e-86, Method: Compositional matrix adjust.
Identities = 124/124 (100%), Positives = 124/124 (100%), Gaps = 0/124 (0%)
Query 9 PPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIP 68
PPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIP
Sbjct 9 PPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIP 68
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ
Sbjct 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
Query 129 RVET 132
RVET
Sbjct 129 RVET 132
>1mhd_D B SMAD3
Length=132
Score = 260 bits (665), Expect = 1e-85, Method: Compositional matrix adjust.
Identities = 123/123 (100%), Positives = 123/123 (100%), Gaps = 0/123 (0%)
Query 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPR 69
PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPR
Sbjct 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPR 69
Query 70 SLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQR 129
SLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQR
Sbjct 70 SLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQR 129
Query 130 VET 132
VET
Sbjct 130 VET 132
>1mhd_C A SMAD3
Length=132
Score = 260 bits (665), Expect = 1e-85, Method: Compositional matrix adjust.
Identities = 123/123 (100%), Positives = 123/123 (100%), Gaps = 0/123 (0%)
Query 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPR 69
PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPR
Sbjct 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPR 69
Query 70 SLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQR 129
SLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQR
Sbjct 70 SLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQR 129
Query 130 VET 132
VET
Sbjct 130 VET 132
>6zmn_A A Mothers against decapentaplegic homolog 3
Length=125
Score = 221 bits (563), Expect = 2e-70, Method: Compositional matrix adjust.
Identities = 116/123 (94%), Positives = 119/123 (97%), Gaps = 3/123 (2%)
Query 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPR 69
P VKRLLGWK+G++ EEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPR
Sbjct 2 PAVKRLLGWKQGDE---EEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPR 58
Query 70 SLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQR 129
SLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQR
Sbjct 59 SLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQR 118
Query 130 VET 132
VET
Sbjct 119 VET 121
>6zmn_B B Mothers against decapentaplegic homolog 3
Length=125
Score = 217 bits (553), Expect = 6e-69, Method: Compositional matrix adjust.
Identities = 114/121 (94%), Positives = 117/121 (97%), Gaps = 3/121 (2%)
Query 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPR 69
P VKRLLGWK+G++ EEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPR
Sbjct 2 PAVKRLLGWKQGDE---EEKWCEKAVKSLVKKLKKTGQLDELEKAITTQNVNTKCITIPR 58
Query 70 SLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQR 129
SLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQR
Sbjct 59 SLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQR 118
Query 130 V 130
V
Sbjct 119 V 119
>6h3r_A A Mothers against decapentaplegic homolog
Length=139
Score = 206 bits (524), Expect = 2e-64, Method: Compositional matrix adjust.
Identities = 108/133 (81%), Positives = 117/133 (88%), Gaps = 10/133 (8%)
Query 8 TPPIVKRLLGWKKGEQ----------NGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITT 57
+ P+VKRLLGWKK NGQEEKW EKAVKSLVKKLKKTG+LDELEKAITT
Sbjct 2 SSPVVKRLLGWKKSXXXXXXXXXXXXNGQEEKWSEKAVKSLVKKLKKTGRLDELEKAITT 61
Query 58 QNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKK 117
QN+NTKC+TIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KK
Sbjct 62 QNMNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKK 121
Query 118 DEVCVNPYHYQRV 130
DEVCVNPYHYQRV
Sbjct 122 DEVCVNPYHYQRV 134
>6h3r_B B Mothers against decapentaplegic homolog
Length=139
Score = 206 bits (524), Expect = 2e-64, Method: Compositional matrix adjust.
Identities = 108/133 (81%), Positives = 117/133 (88%), Gaps = 10/133 (8%)
Query 8 TPPIVKRLLGWKKGEQ----------NGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITT 57
+ P+VKRLLGWKK NGQEEKW EKAVKSLVKKLKKTG+LDELEKAITT
Sbjct 2 SSPVVKRLLGWKKSXXXXXXXXXXXXNGQEEKWSEKAVKSLVKKLKKTGRLDELEKAITT 61
Query 58 QNVNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKK 117
QN+NTKC+TIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHEL+A+E CE+AFN+KK
Sbjct 62 QNMNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKK 121
Query 118 DEVCVNPYHYQRV 130
DEVCVNPYHYQRV
Sbjct 122 DEVCVNPYHYQRV 134
>6tbz_A A Mothers against decapentaplegic homolog 5
Length=131
Score = 191 bits (486), Expect = 9e-59, Method: Compositional matrix adjust.
Identities = 92/126 (73%), Positives = 110/126 (87%), Gaps = 1/126 (1%)
Query 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCITIP 68
P VKRLLGWK+GEQNGQEEKW EKAV +LVKKLKK G ++ELEKA+++ +KC+TIP
Sbjct 3 PAVKRLLGWKQGEQNGQEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIP 62
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPYHY+
Sbjct 63 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYK 122
Query 129 RVETPV 134
RVE+PV
Sbjct 123 RVESPV 128
>6fzs_B B Mothers against decapentaplegic homolog 5
Length=132
Score = 182 bits (462), Expect = 3e-55, Method: Compositional matrix adjust.
Identities = 90/130 (69%), Positives = 110/130 (85%), Gaps = 4/130 (3%)
Query 7 FTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCI 65
FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++ +KC+
Sbjct 4 FTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCV 60
Query 66 TIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPY 125
TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPY
Sbjct 61 TIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPY 120
Query 126 HYQRVETPVL 135
HY+RVE+PVL
Sbjct 121 HYKRVESPVL 130
>6fzt_B B Mothers against decapentaplegic homolog 9
Length=140
Score = 182 bits (461), Expect = 6e-55, Method: Compositional matrix adjust.
Identities = 92/129 (71%), Positives = 107/129 (83%), Gaps = 4/129 (3%)
Query 7 FTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCI 65
FT P VKRLLGWK+G++ EEKW EKAV SLVKKLKK G +DELE+A++ +KC+
Sbjct 13 FTSPAVKRLLGWKQGDE---EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCV 69
Query 66 TIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPY 125
TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ EVC+NPY
Sbjct 70 TIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPY 129
Query 126 HYQRVETPV 134
HY+RVETPV
Sbjct 130 HYRRVETPV 138
>6fzs_A A Mothers against decapentaplegic homolog 5
Length=132
Score = 179 bits (454), Expect = 4e-54, Method: Compositional matrix adjust.
Identities = 88/128 (69%), Positives = 108/128 (84%), Gaps = 4/128 (3%)
Query 7 FTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCI 65
FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++ +KC+
Sbjct 4 FTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCV 60
Query 66 TIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPY 125
TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPY
Sbjct 61 TIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPY 120
Query 126 HYQRVETP 133
HY+RVE+P
Sbjct 121 HYKRVESP 128
>6fzt_A A Mothers against decapentaplegic homolog 9
Length=140
Score = 177 bits (450), Expect = 3e-53, Method: Compositional matrix adjust.
Identities = 90/126 (71%), Positives = 105/126 (83%), Gaps = 4/126 (3%)
Query 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCITIP 68
P VKRLLGWK+G++ EEKW EKAV SLVKKLKK G +DELE+A++ +KC+TIP
Sbjct 16 PAVKRLLGWKQGDE---EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCVTIP 72
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ EVC+NPYHY+
Sbjct 73 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYR 132
Query 129 RVETPV 134
RVETPV
Sbjct 133 RVETPV 138
>5x6m_A B Mothers against decapentaplegic homolog 5
Length=150
Score = 175 bits (443), Expect = 4e-52, Method: Compositional matrix adjust.
Identities = 86/125 (69%), Positives = 106/125 (85%), Gaps = 4/125 (3%)
Query 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCITIP 68
P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++ +KC+TIP
Sbjct 13 PAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIP 69
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPYHY+
Sbjct 70 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYK 129
Query 129 RVETP 133
RVE+P
Sbjct 130 RVESP 134
>6tce_A A Mothers against decapentaplegic homolog 5
Length=134
Score = 174 bits (440), Expect = 6e-52, Method: Compositional matrix adjust.
Identities = 87/128 (68%), Positives = 105/128 (82%), Gaps = 2/128 (2%)
Query 10 PIVKRLLGWKKGEQN-GQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCITI 67
P VKRLLGWK +EEKW EKAV +LVKKLKK G ++ELEKA+++ +KC+TI
Sbjct 5 PAVKRLLGWKXXXXXXDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTI 64
Query 68 PRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHY 127
PRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPYHY
Sbjct 65 PRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHY 124
Query 128 QRVETPVL 135
+RVE+PVL
Sbjct 125 KRVESPVL 132
>5x6g_B B Mothers against decapentaplegic homolog 5
Length=150
Score = 174 bits (441), Expect = 7e-52, Method: Compositional matrix adjust.
Identities = 86/126 (68%), Positives = 106/126 (84%), Gaps = 4/126 (3%)
Query 8 TPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCIT 66
T P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++ +KC+T
Sbjct 11 TSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVT 67
Query 67 IPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYH 126
IPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPYH
Sbjct 68 IPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYH 127
Query 127 YQRVET 132
Y+RVE+
Sbjct 128 YKRVES 133
>3kmp_A A SMAD1-MH1
Length=124
Score = 173 bits (438), Expect = 1e-51, Method: Compositional matrix adjust.
Identities = 87/127 (69%), Positives = 104/127 (82%), Gaps = 4/127 (3%)
Query 7 FTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCI 65
FT P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++ + C+
Sbjct 1 FTSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPSNCV 57
Query 66 TIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPY 125
TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ EVC+NPY
Sbjct 58 TIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPY 117
Query 126 HYQRVET 132
HY+RVE+
Sbjct 118 HYKRVES 124
>5x6g_A A Mothers against decapentaplegic homolog 5
Length=150
Score = 173 bits (438), Expect = 2e-51, Method: Compositional matrix adjust.
Identities = 86/125 (69%), Positives = 105/125 (84%), Gaps = 4/125 (3%)
Query 8 TPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCIT 66
T P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++ +KC+T
Sbjct 11 TSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVT 67
Query 67 IPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYH 126
IPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPYH
Sbjct 68 IPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYH 127
Query 127 YQRVE 131
Y+RVE
Sbjct 128 YKRVE 132
>5x6m_D A Mothers against decapentaplegic homolog 5
Length=150
Score = 172 bits (437), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 85/124 (69%), Positives = 105/124 (85%), Gaps = 4/124 (3%)
Query 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCITIP 68
P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++ +KC+TIP
Sbjct 13 PAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIP 69
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPYHY+
Sbjct 70 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYK 129
Query 129 RVET 132
RVE+
Sbjct 130 RVES 133
>5x6m_E E Mothers against decapentaplegic homolog 5
Length=150
Score = 172 bits (436), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 85/124 (69%), Positives = 105/124 (85%), Gaps = 4/124 (3%)
Query 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCITIP 68
P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++ +KC+TIP
Sbjct 13 PAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIP 69
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPYHY+
Sbjct 70 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYK 129
Query 129 RVET 132
RVE+
Sbjct 130 RVES 133
>5x6m_H F Mothers against decapentaplegic homolog 5
Length=150
Score = 172 bits (436), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 85/124 (69%), Positives = 105/124 (85%), Gaps = 4/124 (3%)
Query 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCITIP 68
P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA+++ +KC+TIP
Sbjct 13 PAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIP 69
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPYHY+
Sbjct 70 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYK 129
Query 129 RVET 132
RVE+
Sbjct 130 RVES 133
>3kmp_B B SMAD1-MH1
Length=124
Score = 170 bits (431), Expect = 8e-51, Method: Compositional matrix adjust.
Identities = 86/126 (68%), Positives = 103/126 (82%), Gaps = 4/126 (3%)
Query 8 TPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCIT 66
T P VKRLLGWK+G++ EEKW EKAV +LVKKLKK G ++ELEKA++ + C+T
Sbjct 2 TSPAVKRLLGWKQGDE---EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPSNCVT 58
Query 67 IPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYH 126
IPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ EVC+NPYH
Sbjct 59 IPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYH 118
Query 127 YQRVET 132
Y+RVE+
Sbjct 119 YKRVES 124
>1dd1_C C SMAD4
Length=268
Score = 166 bits (419), Expect = 4e-47, Method: Compositional matrix adjust.
Identities = 94/225 (42%), Positives = 128/225 (57%), Gaps = 40/225 (18%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 36 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 95
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 96 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 155
Query 345 NQE-----------------------------------FAALLAQSVNQGFEAVYQLTRM 369
++ A ++ S G V L R+
Sbjct 156 LRQCHRQMQQQAATAQAAAAAQAAAVAGNXXXXXXXXXXAPAISLSAAAGI-GVDDLRRL 214
Query 370 CTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct 215 CILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 259
>1dd1_B B SMAD4
Length=268
Score = 166 bits (419), Expect = 4e-47, Method: Compositional matrix adjust.
Identities = 94/225 (42%), Positives = 128/225 (57%), Gaps = 40/225 (18%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 36 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 95
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 96 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 155
Query 345 NQE-----------------------------------FAALLAQSVNQGFEAVYQLTRM 369
++ A ++ S G V L R+
Sbjct 156 LRQCHRQMQQQAATAQAAAAAQAAAVAGNIXXXXXXXXXAPAISLSAAAGI-GVDDLRRL 214
Query 370 CTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
C +RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct 215 CILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 259
>1g88_C C SMAD4
Length=268
Score = 163 bits (413), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 93/225 (41%), Positives = 127/225 (56%), Gaps = 40/225 (18%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 36 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 95
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 96 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 155
Query 345 NQE-----------------------------------FAALLAQSVNQGFEAVYQLTRM 369
++ A ++ S G V L R+
Sbjct 156 LRQCHRQMQQQAATAQAAAAAQAAAVXXXXXXXXXXXXXAPAISLSAAAGI-GVDDLRRL 214
Query 370 CTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
C +RMSFVKGWG +Y Q++ TPCWIE+HL+ LQ LD+VL M
Sbjct 215 CILRMSFVKGWGPDYPSQSIKETPCWIEIHLHRALQLLDEVLHTM 259
>1g88_B B SMAD4
Length=268
Score = 163 bits (413), Expect = 4e-46, Method: Compositional matrix adjust.
Identities = 93/225 (41%), Positives = 127/225 (56%), Gaps = 40/225 (18%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 36 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 95
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 96 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 155
Query 345 NQE-----------------------------------FAALLAQSVNQGFEAVYQLTRM 369
++ A ++ S G V L R+
Sbjct 156 LRQCHRQMQQQAATAQAAAAAQAAAVAXXXXXXXXXXXXAPAISLSAAAGI-GVDDLRRL 214
Query 370 CTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
C +RMSFVKGWG +Y Q++ TPCWIE+HL+ LQ LD+VL M
Sbjct 215 CILRMSFVKGWGPDYPSQSIKETPCWIEIHLHRALQLLDEVLHTM 259
>1u7v_C B Mothers against decapentaplegic homolog 4
Length=236
Score = 161 bits (408), Expect = 6e-46, Method: Compositional matrix adjust.
Identities = 92/224 (41%), Positives = 125/224 (56%), Gaps = 38/224 (17%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 7 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 66
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 67 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 126
Query 345 NQEFAALLAQSVNQGFE----------------------------------AVYQLTRMC 370
++ + Q V L R+C
Sbjct 127 LRQCHRQMQQQAATAQAAAAAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXIGVDDLRRLC 186
Query 371 TIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
+RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct 187 ILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 230
>5x6h_A B Mothers against decapentaplegic homolog 5
Length=150
Score = 158 bits (400), Expect = 7e-46, Method: Compositional matrix adjust.
Identities = 81/124 (65%), Positives = 98/124 (79%), Gaps = 4/124 (3%)
Query 10 PIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQNVNTKCITIP 68
P VKRLL EEKW EKAV +LVKKLKK G ++ELEKA+++ +KC+TIP
Sbjct 13 PAVKRLL---XXXXXXXEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVTIP 69
Query 69 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 128
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +++CEF F K+ EVC+NPYHY+
Sbjct 70 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYK 129
Query 129 RVET 132
RVE+
Sbjct 130 RVES 133
>1mr1_B B Mothers against decapentaplegic homolog 4
Length=235
Score = 161 bits (408), Expect = 8e-46, Method: Compositional matrix adjust.
Identities = 91/224 (41%), Positives = 123/224 (55%), Gaps = 38/224 (17%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 3 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 62
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 63 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 122
Query 345 NQE----------------------------------FAALLAQSVNQGFEAVYQLTRMC 370
++ V L R+C
Sbjct 123 LRQCHRQMQQQAAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDDLRRLC 182
Query 371 TIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
+RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct 183 ILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 226
>1ygs_A A SMAD4
Length=234
Score = 161 bits (407), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 91/224 (41%), Positives = 123/224 (55%), Gaps = 38/224 (17%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 2 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 61
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 62 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 121
Query 345 NQE----------------------------------FAALLAQSVNQGFEAVYQLTRMC 370
++ V L R+C
Sbjct 122 LRQCHRQMQQQAATAQAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDDLRRLC 181
Query 371 TIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
+RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct 182 ILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 225
>1mr1_A A Mothers against decapentaplegic homolog 4
Length=235
Score = 161 bits (407), Expect = 1e-45, Method: Compositional matrix adjust.
Identities = 91/224 (41%), Positives = 123/224 (55%), Gaps = 38/224 (17%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 3 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 62
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 63 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 122
Query 345 NQE----------------------------------FAALLAQSVNQGFEAVYQLTRMC 370
++ V L R+C
Sbjct 123 LRQCHRQMQQQAATAQAAAAAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDDLRRLC 182
Query 371 TIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
+RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct 183 ILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 226
>1dd1_A A SMAD4
Length=268
Score = 161 bits (408), Expect = 2e-45, Method: Compositional matrix adjust.
Identities = 92/224 (41%), Positives = 125/224 (56%), Gaps = 38/224 (17%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 36 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 95
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 96 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 155
Query 345 NQEFAALLAQSVNQGFE----------------------------------AVYQLTRMC 370
++ + Q V L R+C
Sbjct 156 LRQCHRQMQQQAATAQAAAAAXXXXXXXXXXXXXXXXXXXXXXXXXXAAGIGVDDLRRLC 215
Query 371 TIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
+RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct 216 ILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 259
>5c4v_A A Mothers against decapentaplegic homolog 4
Length=258
Score = 160 bits (404), Expect = 4e-45, Method: Compositional matrix adjust.
Identities = 90/221 (41%), Positives = 122/221 (55%), Gaps = 38/221 (17%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 29 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 88
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 89 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 148
Query 345 NQE----------------------------------FAALLAQSVNQGFEAVYQLTRMC 370
++ V L R+C
Sbjct 149 LRQCHRQMQQQAATAQAAAAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGVDDLRRLC 208
Query 371 TIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVL 411
+RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL
Sbjct 209 ILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVL 249
>5c4v_C E Mothers against decapentaplegic homolog 4
Length=258
Score = 160 bits (404), Expect = 5e-45, Method: Compositional matrix adjust.
Identities = 90/221 (41%), Positives = 122/221 (55%), Gaps = 38/221 (17%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 29 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 88
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 89 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 148
Query 345 NQE----------------------------------FAALLAQSVNQGFEAVYQLTRMC 370
++ V L R+C
Sbjct 149 LRQCHRQMQQQAATAQAAAAAQAAXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDDLRRLC 208
Query 371 TIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVL 411
+RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL
Sbjct 209 ILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVL 249
>5c4v_B C Mothers against decapentaplegic homolog 4
Length=258
Score = 159 bits (403), Expect = 6e-45, Method: Compositional matrix adjust.
Identities = 90/221 (41%), Positives = 122/221 (55%), Gaps = 38/221 (17%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 29 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 88
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 89 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 148
Query 345 NQE----------------------------------FAALLAQSVNQGFEAVYQLTRMC 370
++ V L R+C
Sbjct 149 LRQCHRQMQQQAATAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVDDLRRLC 208
Query 371 TIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVL 411
+RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL
Sbjct 209 ILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVL 249
>1g88_A A SMAD4
Length=268
Score = 159 bits (402), Expect = 2e-44, Method: Compositional matrix adjust.
Identities = 91/224 (41%), Positives = 124/224 (55%), Gaps = 38/224 (17%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 36 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 95
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ G P V KI P +K+F+
Sbjct 96 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 155
Query 345 NQEFAALLAQSVNQGFE----------------------------------AVYQLTRMC 370
++ + Q V L R+C
Sbjct 156 LRQCHRQMQQQAATAQAAAAAXXXXXXXXXXXXXXXXXXXXXXXXXXAAGIGVDDLRRLC 215
Query 371 TIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
+RMSFVKGWG +Y Q++ TPCWIE+HL+ LQ LD+VL M
Sbjct 216 ILRMSFVKGWGPDYPSQSIKETPCWIEIHLHRALQLLDEVLHTM 259
>1u7f_B B Mothers against decapentaplegic homolog 4
Length=239
Score = 155 bits (392), Expect = 2e-43, Method: Compositional matrix adjust.
Identities = 89/224 (40%), Positives = 121/224 (54%), Gaps = 38/224 (17%)
Query 229 PAFWCSISYYELNQRVGETFH--ASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELT 286
P +WCSI+Y+E++ +VGETF +S P +TVDG+ DPS +RFCLG LSNV+R A+E
Sbjct 7 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 66
Query 287 RRHIGRGVRLYYIG-GEVFAECLSDSAIFVQSPNCNQRYGWHPA-TVCKIPPGCNLKIFN 344
R HIG+GV+L G G+V+ CLSD A+FVQS ++ V KI P +K+F+
Sbjct 67 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREXXXXXXDAVHKIYPSAYIKVFD 126
Query 345 NQE----------------------------------FAALLAQSVNQGFEAVYQLTRMC 370
++ V L R+C
Sbjct 127 LRQCHRQMQQQAATAQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXIGVDDLRRLC 186
Query 371 TIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQM 414
+RMSFVKGWG +Y RQ++ TPCWIE+HL+ LQ LD+VL M
Sbjct 187 ILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 230
>5nm9_A A Mothers against decapentaplegic homolog
Length=143
Score = 136 bits (342), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 64/110 (58%), Positives = 87/110 (79%), Gaps = 3/110 (3%)
Query 23 QNGQEEKWCEKAVKSLVKKLK-KTGQLDELEKAITTQNVN-TKCITIPRSLDGRLQVSHR 80
Q G+ E + ++AV+SLVKKLK K +LD L A+T+ + +KC+TI R+LDGRLQV+ +
Sbjct 25 QGGESENFAKRAVESLVKKLKDKRDELDALITAVTSNGIQQSKCVTIARTLDGRLQVAGK 84
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
KG PHVIY R+WRWPDLH +EL+ ++LC+FAF++K D VCVNPYHY+RV
Sbjct 85 KGFPHVIYSRIWRWPDLHK-NELKHIKLCKFAFDLKLDHVCVNPYHYERV 133
>5nm9_B B Mothers against decapentaplegic homolog
Length=143
Score = 135 bits (341), Expect = 3e-37, Method: Compositional matrix adjust.
Identities = 64/110 (58%), Positives = 87/110 (79%), Gaps = 3/110 (3%)
Query 23 QNGQEEKWCEKAVKSLVKKLK-KTGQLDELEKAITTQNVN-TKCITIPRSLDGRLQVSHR 80
Q G+ E + ++AV+SLVKKLK K +LD L A+T+ + +KC+TI R+LDGRLQV+ +
Sbjct 25 QGGESENFAKRAVESLVKKLKDKRDELDALITAVTSNGIQQSKCVTIARTLDGRLQVAGK 84
Query 81 KGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
KG PHVIY R+WRWPDLH +EL+ ++LC+FAF++K D VCVNPYHY+RV
Sbjct 85 KGFPHVIYSRIWRWPDLHK-NELKHIKLCKFAFDLKLDHVCVNPYHYERV 133
>5mez_A A MH1 domain of human Smad4
Length=135
Score = 121 bits (303), Expect = 8e-32, Method: Compositional matrix adjust.
Identities = 63/114 (55%), Positives = 85/114 (75%), Gaps = 3/114 (3%)
Query 22 EQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIPRSLDGRLQVSH 79
Q G+ E + ++A++SLVKKLK+ L AITT + +KC+TI R+LDGRLQV+
Sbjct 22 RQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAG 81
Query 80 RKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRVETP 133
RKG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV +P
Sbjct 82 RKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVSP 134
>3qsv_B B Mothers against decapentaplegic homolog 4
Length=132
Score = 119 bits (297), Expect = 4e-31, Method: Compositional matrix adjust.
Identities = 62/111 (56%), Positives = 83/111 (75%), Gaps = 3/111 (3%)
Query 22 EQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIPRSLDGRLQVSH 79
Q G+ E + ++A++SLVKKLK+ L AITT + +KC+TI R+LDGRLQV+
Sbjct 19 RQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAG 78
Query 80 RKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
RKG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV
Sbjct 79 RKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERV 128
>3qsv_A A Mothers against decapentaplegic homolog 4
Length=132
Score = 119 bits (297), Expect = 4e-31, Method: Compositional matrix adjust.
Identities = 62/111 (56%), Positives = 83/111 (75%), Gaps = 3/111 (3%)
Query 22 EQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIPRSLDGRLQVSH 79
Q G+ E + ++A++SLVKKLK+ L AITT + +KC+TI R+LDGRLQV+
Sbjct 19 RQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAG 78
Query 80 RKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
RKG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV
Sbjct 79 RKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERV 128
>3qsv_D D Mothers against decapentaplegic homolog 4
Length=132
Score = 119 bits (297), Expect = 6e-31, Method: Compositional matrix adjust.
Identities = 62/111 (56%), Positives = 83/111 (75%), Gaps = 3/111 (3%)
Query 22 EQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIPRSLDGRLQVSH 79
Q G+ E + ++A++SLVKKLK+ L AITT + +KC+TI R+LDGRLQV+
Sbjct 19 RQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAG 78
Query 80 RKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
RKG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV
Sbjct 79 RKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERV 128
>5mey_A A MH1 domain of human Smad4
Length=135
Score = 119 bits (297), Expect = 6e-31, Method: Compositional matrix adjust.
Identities = 62/111 (56%), Positives = 83/111 (75%), Gaps = 3/111 (3%)
Query 22 EQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIPRSLDGRLQVSH 79
Q G+ E + ++A++SLVKKLK+ L AITT + +KC+TI R+LDGRLQV+
Sbjct 22 RQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAG 81
Query 80 RKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
RKG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV
Sbjct 82 RKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERV 131
>5mf0_B B MH1 domain of human Smad4
Length=135
Score = 119 bits (297), Expect = 6e-31, Method: Compositional matrix adjust.
Identities = 62/111 (56%), Positives = 83/111 (75%), Gaps = 3/111 (3%)
Query 22 EQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIPRSLDGRLQVSH 79
Q G+ E + ++A++SLVKKLK+ L AITT + +KC+TI R+LDGRLQV+
Sbjct 22 RQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAG 81
Query 80 RKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
RKG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV
Sbjct 82 RKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERV 131
>3qsv_C C Mothers against decapentaplegic homolog 4
Length=132
Score = 118 bits (296), Expect = 7e-31, Method: Compositional matrix adjust.
Identities = 62/111 (56%), Positives = 83/111 (75%), Gaps = 3/111 (3%)
Query 22 EQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIPRSLDGRLQVSH 79
Q G+ E + ++A++SLVKKLK+ L AITT + +KC+TI R+LDGRLQV+
Sbjct 19 RQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAG 78
Query 80 RKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
RKG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV
Sbjct 79 RKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERV 128
>5mf0_A A MH1 domain of human Smad4
Length=135
Score = 118 bits (296), Expect = 7e-31, Method: Compositional matrix adjust.
Identities = 62/111 (56%), Positives = 83/111 (75%), Gaps = 3/111 (3%)
Query 22 EQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIPRSLDGRLQVSH 79
Q G+ E + ++A++SLVKKLK+ L AITT + +KC+TI R+LDGRLQV+
Sbjct 22 RQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAG 81
Query 80 RKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
RKG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV
Sbjct 82 RKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERV 131
>5mez_B B MH1 domain of human Smad4
Length=135
Score = 118 bits (296), Expect = 8e-31, Method: Compositional matrix adjust.
Identities = 62/111 (56%), Positives = 83/111 (75%), Gaps = 3/111 (3%)
Query 22 EQNGQEEKWCEKAVKSLVKKLKKTGQLD-ELEKAITTQNVN-TKCITIPRSLDGRLQVSH 79
Q G+ E + ++A++SLVKKLK+ L AITT + +KC+TI R+LDGRLQV+
Sbjct 22 RQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAG 81
Query 80 RKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQRV 130
RKG PHVIY RLWRWPDLH +EL+ ++ C++AF++K D VCVNPYHY+RV
Sbjct 82 RKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERV 131
>7cd1_D D Mothers against decapentaplegic homolog 7
Length=187
Score = 85.9 bits (211), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 57/170 (34%), Positives = 89/170 (52%), Gaps = 6/170 (4%)
Query 232 WCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIG 291
WC ++Y+E RVG + +PS+ D F D FCLG L++ N++ V+ R IG
Sbjct 22 WCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIG 79
Query 292 RGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAAL 351
G++L V+ S IF++S + V K+ PG ++K F+ ++ +L
Sbjct 80 CGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSL 138
Query 352 LAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 401
Q N E + Q T+++SFVKGWG Y RQ ++S PCW+E+ N
Sbjct 139 --QRPND-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFN 185
>7cd1_C C Mothers against decapentaplegic homolog 7
Length=187
Score = 85.9 bits (211), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 57/170 (34%), Positives = 89/170 (52%), Gaps = 6/170 (4%)
Query 232 WCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIG 291
WC ++Y+E RVG + +PS+ D F D FCLG L++ N++ V+ R IG
Sbjct 22 WCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIG 79
Query 292 RGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAAL 351
G++L V+ S IF++S + V K+ PG ++K F+ ++ +L
Sbjct 80 CGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSL 138
Query 352 LAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 401
Q N E + Q T+++SFVKGWG Y RQ ++S PCW+E+ N
Sbjct 139 --QRPND-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFN 185
>7cd1_B B Mothers against decapentaplegic homolog 7
Length=187
Score = 85.9 bits (211), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 57/170 (34%), Positives = 89/170 (52%), Gaps = 6/170 (4%)
Query 232 WCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIG 291
WC ++Y+E RVG + +PS+ D F D FCLG L++ N++ V+ R IG
Sbjct 22 WCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIG 79
Query 292 RGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAAL 351
G++L V+ S IF++S + V K+ PG ++K F+ ++ +L
Sbjct 80 CGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSL 138
Query 352 LAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 401
Q N E + Q T+++SFVKGWG Y RQ ++S PCW+E+ N
Sbjct 139 --QRPND-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFN 185
>7cd1_A A Mothers against decapentaplegic homolog 7
Length=187
Score = 85.9 bits (211), Expect = 2e-18, Method: Compositional matrix adjust.
Identities = 57/170 (34%), Positives = 89/170 (52%), Gaps = 6/170 (4%)
Query 232 WCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIG 291
WC ++Y+E RVG + +PS+ D F D FCLG L++ N++ V+ R IG
Sbjct 22 WCVVAYWEEKTRVGRLYCVQEPSL--DIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIG 79
Query 292 RGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAAL 351
G++L V+ S IF++S + V K+ PG ++K F+ ++ +L
Sbjct 80 CGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYEKAYSL 138
Query 352 LAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 401
Q N E + Q T+++SFVKGWG Y RQ ++S PCW+E+ N
Sbjct 139 --QRPND-HEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEVIFN 185
>4r9p_A A RE28239p
Length=242
Score = 50.8 bits (120), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 41/186 (22%), Positives = 80/186 (43%), Gaps = 20/186 (11%)
Query 221 LQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRN 280
L T + W + +E N+RV + + A P +T++G D + R L N R+
Sbjct 48 LDKWTQIDDEIWAKVIVFERNRRVAKAY-ARAPVLTINGSDDGFDGMRIGLCGFDNPMRD 106
Query 281 AAVELTRRHIGRGVRLYY-IGGEVFAECLSDSAIFVQ----SPNCNQRYGWHPATVCKIP 335
+ +R IG+GV++ G + + S ++V+ SPN G A + K+P
Sbjct 107 QKTDEMKRVIGQGVKIKMDDAGNILIRRYAKSNVYVKSTASSPNEETSIG---AEILKLP 163
Query 336 PGC-----NLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVT 390
+K+F+ ++F + + + + + + +L C ++FVK +
Sbjct 164 NQALESEKIVKLFDMKKFQSNVNRELRRAYPDRRRLETQCLSAVAFVKS------ENDIL 217
Query 391 STPCWI 396
P W+
Sbjct 218 ECPIWV 223
Lambda K H a alpha
0.319 0.135 0.431 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 41837851344
Database: unitmol_20240403.fasta
Posted date: Apr 4, 2024 8:53 PM
Number of letters in database: 237,935,689
Number of sequences in database: 829,018
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40