[Multiple Alignment(many alignments)]
[Alignment Bar(many alignments)]
[show plain BLAST file]
BLASTP 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: unitmol_20241002.fasta
877,468 sequences; 253,696,794 total letters
Query= sp|P02649|APOE_HUMAN Apolipoprotein E OS=Homo sapiens OX=9606
GN=APOE PE=1 SV=1
Length=317
Score E
Sequences producing significant alignments: (Bits) Value
2l7b_A A Apolipoprotein E 565 0.0
2kc3_A A Apolipoprotein E 355 5e-124
1bz4_A A PROTEIN (APOLIPOPROTEIN E) 281 4e-95
1lpe_A A APOLIPOPROTEIN E3 281 5e-95
1le2_A A APOLIPOPROTEIN E2 278 6e-94
1gs9_A A APOLIPOPROTEIN E 276 6e-93
7uvj_A A Apolipoprotein E 270 6e-91
7uvj_B B Apolipoprotein E 270 7e-91
1h7i_A A APOLIPOPROTEIN E 272 7e-91
1ea8_A A APOLIPOPROTEIN E 271 9e-91
6nco_A A Apolipoprotein E 269 5e-90
6ncn_A A Apolipoprotein E 269 5e-90
1le4_A A APOLIPOPROTEIN E4 266 3e-89
8grx_C C Apolipoprotein E 263 5e-88
8grx_A A Apolipoprotein E 263 5e-88
1b68_A A APOLIPOPROTEIN E 263 3e-87
7fcr_A A Apolipoprotein E 262 4e-87
1ya9_A A Apolipoprotein E 262 5e-87
8cdy_A A Maltodextrin-binding protein,Apolipoprotein E 274 8e-86
8ax9_A A Maltose/maltodextrin-binding periplasmic protein,Apolipo... 274 8e-86
8ce0_A A Maltodextrin-binding protein,Apolipoprotein E 274 8e-86
6cfe_A A Mutant of Apolipoprotein E3 (APO-E3) 252 1e-83
6iwb_C C Apolipoprotein E 248 5e-82
6iwb_A A Apolipoprotein E 246 4e-81
1or3_A A PROTEIN (APOLIPOPROTEIN E) 241 4e-79
7fcs_A A Apolipoprotein E 236 1e-76
1nfn_A A APOLIPOPROTEIN E3 233 2e-75
1or2_A A APOLIPOPROTEIN E 229 5e-74
1nfo_A A APOLIPOPROTEIN E2 225 2e-72
8ax8_A A Maltose/maltodextrin-binding periplasmic protein,Apolipo... 234 1e-70
6v7m_B B Apolipoprotein E 164 4e-50
6v7m_A A Apolipoprotein E 128 8e-36
1oef_A A APOLIPOPROTEIN E 52.8 2e-08
1oeg_A A APOLIPOPROTEIN E 49.3 4e-07
6cm1_C C Apolipoprotein A-I 52.0 1e-06
6cm1_B B Apolipoprotein A-I 52.0 1e-06
6clz_C C Apolipoprotein A-I 52.0 1e-06
6clz_B B Apolipoprotein A-I 52.0 1e-06
2kny_A A LRP-1, linker, Apo-E 40.4 0.002
3s84_B B Apolipoprotein A-IV 42.4 0.003
3s84_A A Apolipoprotein A-IV 42.4 0.003
6pts_B C Apolipoprotein A-I 40.0 0.013
6pts_A A Apolipoprotein A-I 40.0 0.013
6ptw_A A Apolipoprotein A-I 40.0 0.013
6ptw_B C Apolipoprotein A-I 40.0 0.013
6cc9_A A Apolipoprotein A-I 40.0 0.013
6cc9_C C Apolipoprotein A-I 40.0 0.013
6w4e_A A Apolipoprotein A-I 40.0 0.013
6w4f_B D Apolipoprotein A-I 40.0 0.013
6w4f_A A Apolipoprotein A-I 40.0 0.013
4v6m_F A1 Apolipoprotein A-I 40.0 0.013
4v6m_E A0 Apolipoprotein A-I 40.0 0.013
6ccx_C C Apolipoprotein A-I 40.0 0.013
6ccx_A A Apolipoprotein A-I 40.0 0.013
6cch_C C Apolipoprotein A-I 40.0 0.013
6cch_A A Apolipoprotein A-I 40.0 0.013
6w4e_B D Apolipoprotein A-I 40.0 0.013
2msd_A A Apolipoprotein A-I 40.0 0.013
2mse_A A Apolipoprotein A-I 40.0 0.013
2mse_B C Apolipoprotein A-I 40.0 0.013
2msd_B C Apolipoprotein A-I 40.0 0.013
2msc_A A Apolipoprotein A-I 40.0 0.013
2msc_B C Apolipoprotein A-I 40.0 0.013
3k2s_B B Apolipoprotein A-I 40.4 0.014
3k2s_A A Apolipoprotein A-I 40.4 0.014
1av1_A A APOLIPOPROTEIN A-I 40.0 0.015
1av1_B B APOLIPOPROTEIN A-I 40.0 0.015
1av1_D D APOLIPOPROTEIN A-I 40.0 0.015
1av1_C C APOLIPOPROTEIN A-I 40.0 0.015
7rsc_C D Apolipoprotein A-I 38.9 0.029
7rse_D E Apolipoprotein A-I 38.9 0.029
7rse_C D Apolipoprotein A-I 38.9 0.029
7rsc_D E Apolipoprotein A-I 38.9 0.029
2n5e_B B Apolipoprotein A-I 38.5 0.035
2n5e_A A Apolipoprotein A-I 38.5 0.035
3r2p_A A Apolipoprotein A-I 37.0 0.13
2lem_A A Apolipoprotein A-I 33.9 1.4
>2l7b_A A Apolipoprotein E
Length=307
Score = 565 bits (1457), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 294/299 (98%), Positives = 294/299 (98%), Gaps = 0/299 (0%)
Query 19 KVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQEL 78
KVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQEL
Sbjct 9 KVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQEL 68
Query 79 RALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRG 138
RALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRG
Sbjct 69 RALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRG 128
Query 139 EVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRER 198
EVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRER
Sbjct 129 EVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRER 188
Query 199 LGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVR 258
LGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVR
Sbjct 189 LGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVR 248
Query 259 AKLEEQAQQIRLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGTSAAPVPSDNH 317
AKLEEQAQQIRLQAEA QARLKS FEPL EDMQRQWAG VEKVQAA GTSAAPVPSDNH
Sbjct 249 AKLEEQAQQIRLQAEAAQARLKSRFEPLAEDMQRQWAGQVEKVQAAEGTSAAPVPSDNH 307
>2kc3_A A Apolipoprotein E
Length=184
Score = 355 bits (912), Expect = 5e-124, Method: Compositional matrix adjust.
Identities = 183/183 (100%), Positives = 183/183 (100%), Gaps = 0/183 (0%)
Query 19 KVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQEL 78
KVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQEL
Sbjct 2 KVEQAVETEPEPELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQEL 61
Query 79 RALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRG 138
RALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRG
Sbjct 62 RALMDETMKELKAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRG 121
Query 139 EVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRER 198
EVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRER
Sbjct 122 EVQAMLGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRER 181
Query 199 LGP 201
LGP
Sbjct 182 LGP 184
>1bz4_A A PROTEIN (APOLIPOPROTEIN E)
Length=144
Score = 281 bits (718), Expect = 4e-95, Method: Compositional matrix adjust.
Identities = 144/144 (100%), Positives = 144/144 (100%), Gaps = 0/144 (0%)
Query 40 SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ 99
SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ
Sbjct 1 SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ 60
Query 100 LTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHL 159
LTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHL
Sbjct 61 LTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHL 120
Query 160 RKLRKRLLRDADDLQKRLAVYQAG 183
RKLRKRLLRDADDLQKRLAVYQAG
Sbjct 121 RKLRKRLLRDADDLQKRLAVYQAG 144
>1lpe_A A APOLIPOPROTEIN E3
Length=144
Score = 281 bits (718), Expect = 5e-95, Method: Compositional matrix adjust.
Identities = 144/144 (100%), Positives = 144/144 (100%), Gaps = 0/144 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 1 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 60
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 61 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 120
Query 161 KLRKRLLRDADDLQKRLAVYQAGA 184
KLRKRLLRDADDLQKRLAVYQAGA
Sbjct 121 KLRKRLLRDADDLQKRLAVYQAGA 144
>1le2_A A APOLIPOPROTEIN E2
Length=144
Score = 278 bits (710), Expect = 6e-94, Method: Compositional matrix adjust.
Identities = 143/144 (99%), Positives = 143/144 (99%), Gaps = 0/144 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 1 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 60
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 61 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 120
Query 161 KLRKRLLRDADDLQKRLAVYQAGA 184
KLRKRLLRDADDLQK LAVYQAGA
Sbjct 121 KLRKRLLRDADDLQKCLAVYQAGA 144
>1gs9_A A APOLIPOPROTEIN E
Length=165
Score = 276 bits (706), Expect = 6e-93, Method: Compositional matrix adjust.
Identities = 143/144 (99%), Positives = 143/144 (99%), Gaps = 0/144 (0%)
Query 40 SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ 99
SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ
Sbjct 22 SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ 81
Query 100 LTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHL 159
LTPVAEETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHL
Sbjct 82 LTPVAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHL 141
Query 160 RKLRKRLLRDADDLQKRLAVYQAG 183
RKLRKRLLRDADDLQKRLAVYQAG
Sbjct 142 RKLRKRLLRDADDLQKRLAVYQAG 165
>7uvj_A A Apolipoprotein E
Length=147
Score = 270 bits (691), Expect = 6e-91, Method: Compositional matrix adjust.
Identities = 139/144 (97%), Positives = 141/144 (98%), Gaps = 0/144 (0%)
Query 40 SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ 99
SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ
Sbjct 4 SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ 63
Query 100 LTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHL 159
LTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQST+ELR RLASHL
Sbjct 64 LTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTKELRNRLASHL 123
Query 160 RKLRKRLLRDADDLQKRLAVYQAG 183
KL+ RLLRDADDLQKRLAVYQAG
Sbjct 124 GKLQDRLLRDADDLQKRLAVYQAG 147
>7uvj_B B Apolipoprotein E
Length=147
Score = 270 bits (691), Expect = 7e-91, Method: Compositional matrix adjust.
Identities = 139/144 (97%), Positives = 141/144 (98%), Gaps = 0/144 (0%)
Query 40 SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ 99
SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ
Sbjct 4 SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ 63
Query 100 LTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHL 159
LTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQST+ELR RLASHL
Sbjct 64 LTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTKELRNRLASHL 123
Query 160 RKLRKRLLRDADDLQKRLAVYQAG 183
KL+ RLLRDADDLQKRLAVYQAG
Sbjct 124 GKLQDRLLRDADDLQKRLAVYQAG 147
>1h7i_A A APOLIPOPROTEIN E
Length=191
Score = 272 bits (695), Expect = 7e-91, Method: Compositional matrix adjust.
Identities = 139/140 (99%), Positives = 140/140 (100%), Gaps = 0/140 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 23 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 82
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 83 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 142
Query 161 KLRKRLLRDADDLQKRLAVY 180
KLR+RLLRDADDLQKRLAVY
Sbjct 143 KLRQRLLRDADDLQKRLAVY 162
>1ea8_A A APOLIPOPROTEIN E
Length=191
Score = 271 bits (694), Expect = 9e-91, Method: Compositional matrix adjust.
Identities = 139/140 (99%), Positives = 140/140 (100%), Gaps = 0/140 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 23 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 82
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 83 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 142
Query 161 KLRKRLLRDADDLQKRLAVY 180
KLR+RLLRDADDLQKRLAVY
Sbjct 143 KLRERLLRDADDLQKRLAVY 162
>6nco_A A Apolipoprotein E
Length=185
Score = 269 bits (688), Expect = 5e-90, Method: Compositional matrix adjust.
Identities = 140/141 (99%), Positives = 140/141 (99%), Gaps = 0/141 (0%)
Query 42 QRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT 101
QRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT
Sbjct 44 QRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT 103
Query 102 PVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRK 161
PVAEETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHLRK
Sbjct 104 PVAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLRK 163
Query 162 LRKRLLRDADDLQKRLAVYQA 182
LRKRLLRDADDLQKRLAVYQA
Sbjct 164 LRKRLLRDADDLQKRLAVYQA 184
>6ncn_A A Apolipoprotein E
Length=185
Score = 269 bits (688), Expect = 5e-90, Method: Compositional matrix adjust.
Identities = 140/141 (99%), Positives = 140/141 (99%), Gaps = 0/141 (0%)
Query 42 QRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT 101
QRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT
Sbjct 44 QRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT 103
Query 102 PVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRK 161
PVAEETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHLRK
Sbjct 104 PVAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLRK 163
Query 162 LRKRLLRDADDLQKRLAVYQA 182
LRKRLLRDADDLQKRLAVYQA
Sbjct 164 LRKRLLRDADDLQKRLAVYQA 184
>1le4_A A APOLIPOPROTEIN E4
Length=144
Score = 266 bits (679), Expect = 3e-89, Method: Compositional matrix adjust.
Identities = 138/139 (99%), Positives = 138/139 (99%), Gaps = 0/139 (0%)
Query 42 QRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT 101
QRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT
Sbjct 2 QRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT 61
Query 102 PVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRK 161
PVAEETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHLRK
Sbjct 62 PVAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLRK 121
Query 162 LRKRLLRDADDLQKRLAVY 180
LRKRLLRDADDLQKRLAVY
Sbjct 122 LRKRLLRDADDLQKRLAVY 140
>8grx_C C Apolipoprotein E
Length=140
Score = 263 bits (671), Expect = 5e-88, Method: Compositional matrix adjust.
Identities = 137/140 (98%), Positives = 137/140 (98%), Gaps = 0/140 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 1 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 60
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
T AEETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 61 TXXAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLR 120
Query 161 KLRKRLLRDADDLQKRLAVY 180
KLRKRLLRDADDLQKRLAVY
Sbjct 121 KLRKRLLRDADDLQKRLAVY 140
>8grx_A A Apolipoprotein E
Length=140
Score = 263 bits (671), Expect = 5e-88, Method: Compositional matrix adjust.
Identities = 137/140 (98%), Positives = 137/140 (98%), Gaps = 0/140 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 1 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 60
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
T AEETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 61 TXXAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLR 120
Query 161 KLRKRLLRDADDLQKRLAVY 180
KLRKRLLRDADDLQKRLAVY
Sbjct 121 KLRKRLLRDADDLQKRLAVY 140
>1b68_A A APOLIPOPROTEIN E
Length=191
Score = 263 bits (671), Expect = 3e-87, Method: Compositional matrix adjust.
Identities = 137/140 (98%), Positives = 137/140 (98%), Gaps = 0/140 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 23 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 82
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
T AEETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 83 TXXAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLR 142
Query 161 KLRKRLLRDADDLQKRLAVY 180
KLRKRLLRDADDLQKRLAVY
Sbjct 143 KLRKRLLRDADDLQKRLAVY 162
>7fcr_A A Apolipoprotein E
Length=193
Score = 262 bits (670), Expect = 4e-87, Method: Compositional matrix adjust.
Identities = 136/141 (96%), Positives = 136/141 (96%), Gaps = 0/141 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 25 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 84
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
T ETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 85 TXXXXETRARLSKELQAAQARLGADMEDVIGRLVQYRGEVQAMLGQSTEELRVRLASHLR 144
Query 161 KLRKRLLRDADDLQKRLAVYQ 181
KLRKRLLRDADDLQKRLAVYQ
Sbjct 145 KLRKRLLRDADDLQKRLAVYQ 165
>1ya9_A A Apolipoprotein E
Length=181
Score = 262 bits (669), Expect = 5e-87, Method: Compositional matrix adjust.
Identities = 133/174 (76%), Positives = 148/174 (85%), Gaps = 0/174 (0%)
Query 30 PELRQQTEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKEL 89
PE+ Q EWQS Q WE AL RFWDYLRWVQTLS+QVQEEL SSQVTQEL ALM++TM E+
Sbjct 3 PEVTDQLEWQSNQPWEQALNRFWDYLRWVQTLSDQVQEELQSSQVTQELTALMEDTMTEV 62
Query 90 KAYKSELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTE 149
KAYK ELEEQL PVAEETRARL KE+QAAQARLGADMED+ RL QYR EV MLGQSTE
Sbjct 63 KAYKKELEEQLGPVAEETRARLGKEVQAAQARLGADMEDLRNRLGQYRNEVHTMLGQSTE 122
Query 150 ELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLV 203
E+R RL++HLRK+RKRL+RDA+DLQKRLAVY+AGA G+SAIRERLGPLV
Sbjct 123 EIRARLSTHLRKMRKRLMRDAEDLQKRLAVYKAGAXXXXXXGVSAIRERLGPLV 176
>8cdy_A A Maltodextrin-binding protein,Apolipoprotein E
Length=675
Score = 274 bits (701), Expect = 8e-86, Method: Compositional matrix adjust.
Identities = 142/143 (99%), Positives = 142/143 (99%), Gaps = 0/143 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 399 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 458
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
TPVAEETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 459 TPVAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLR 518
Query 161 KLRKRLLRDADDLQKRLAVYQAG 183
KLRKRLLRDADDLQKRLAVYQAG
Sbjct 519 KLRKRLLRDADDLQKRLAVYQAG 541
>8ax9_A A Maltose/maltodextrin-binding periplasmic protein,Apolipoprotein
E
Length=675
Score = 274 bits (701), Expect = 8e-86, Method: Compositional matrix adjust.
Identities = 142/143 (99%), Positives = 142/143 (99%), Gaps = 0/143 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 399 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 458
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
TPVAEETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 459 TPVAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLR 518
Query 161 KLRKRLLRDADDLQKRLAVYQAG 183
KLRKRLLRDADDLQKRLAVYQAG
Sbjct 519 KLRKRLLRDADDLQKRLAVYQAG 541
>8ce0_A A Maltodextrin-binding protein,Apolipoprotein E
Length=675
Score = 274 bits (701), Expect = 8e-86, Method: Compositional matrix adjust.
Identities = 142/143 (99%), Positives = 142/143 (99%), Gaps = 0/143 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 399 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 458
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
TPVAEETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 459 TPVAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLR 518
Query 161 KLRKRLLRDADDLQKRLAVYQAG 183
KLRKRLLRDADDLQKRLAVYQAG
Sbjct 519 KLRKRLLRDADDLQKRLAVYQAG 541
>6cfe_A A Mutant of Apolipoprotein E3 (APO-E3)
Length=159
Score = 252 bits (644), Expect = 1e-83, Method: Compositional matrix adjust.
Identities = 129/141 (91%), Positives = 133/141 (94%), Gaps = 0/141 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQV +L LM TM+ELKAYKSELEEQL
Sbjct 19 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVETKLNKLMQRTMEELKAYKSELEEQL 78
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLA+HL
Sbjct 79 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLATHLN 138
Query 161 KLRKRLLRDADDLQKRLAVYQ 181
KLR+RLL DADDLQKRLAVYQ
Sbjct 139 KLRQRLLEDADDLQKRLAVYQ 159
>6iwb_C C Apolipoprotein E
Length=156
Score = 248 bits (633), Expect = 5e-82, Method: Compositional matrix adjust.
Identities = 131/143 (92%), Positives = 134/143 (94%), Gaps = 0/143 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRF +YL WV TLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 10 GQRWELALGRFLEYLSWVSTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 69
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
TPVAEETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHL
Sbjct 70 TPVAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLI 129
Query 161 KLRKRLLRDADDLQKRLAVYQAG 183
L+ RL+ DA DLQKRLAVYQAG
Sbjct 130 ALQLRLIGDAFDLQKRLAVYQAG 152
>6iwb_A A Apolipoprotein E
Length=156
Score = 246 bits (627), Expect = 4e-81, Method: Compositional matrix adjust.
Identities = 130/142 (92%), Positives = 133/142 (94%), Gaps = 0/142 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRF +YL WV TLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 10 GQRWELALGRFLEYLSWVSTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 69
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
TPVAEETRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHL
Sbjct 70 TPVAEETRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLI 129
Query 161 KLRKRLLRDADDLQKRLAVYQA 182
L+ RL+ DA DLQKRLAVYQA
Sbjct 130 ALQLRLIGDAFDLQKRLAVYQA 151
>1or3_A A PROTEIN (APOLIPOPROTEIN E)
Length=165
Score = 241 bits (615), Expect = 4e-79, Method: Compositional matrix adjust.
Identities = 136/143 (95%), Positives = 136/143 (95%), Gaps = 0/143 (0%)
Query 40 SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ 99
SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ
Sbjct 22 SGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ 81
Query 100 LTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHL 159
LT ARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHL
Sbjct 82 LTXXXXXXXARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHL 141
Query 160 RKLRKRLLRDADDLQKRLAVYQA 182
RKLRKRLLRDADDLQKRLAVYQA
Sbjct 142 RKLRKRLLRDADDLQKRLAVYQA 164
>7fcs_A A Apolipoprotein E
Length=193
Score = 236 bits (601), Expect = 1e-76, Method: Compositional matrix adjust.
Identities = 134/141 (95%), Positives = 134/141 (95%), Gaps = 0/141 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL
Sbjct 25 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 84
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
TRARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 85 XXXXXXTRARLSKELQAAQARLGADMEDVVGRLVQYRGEVQAMLGQSTEELRVRLASHLR 144
Query 161 KLRKRLLRDADDLQKRLAVYQ 181
KLRKRLLRDADDLQKRLAVYQ
Sbjct 145 KLRKRLLRDADDLQKRLAVYQ 165
>1nfn_A A APOLIPOPROTEIN E3
Length=191
Score = 233 bits (593), Expect = 2e-75, Method: Compositional matrix adjust.
Identities = 132/142 (93%), Positives = 132/142 (93%), Gaps = 0/142 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ
Sbjct 23 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQX 82
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
RLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 83 XXXXXXXXXRLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 142
Query 161 KLRKRLLRDADDLQKRLAVYQA 182
KLRKRLLRDADDLQKRLAVYQA
Sbjct 143 KLRKRLLRDADDLQKRLAVYQA 164
>1or2_A A APOLIPOPROTEIN E
Length=181
Score = 229 bits (583), Expect = 5e-74, Method: Compositional matrix adjust.
Identities = 130/141 (92%), Positives = 130/141 (92%), Gaps = 0/141 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ
Sbjct 23 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQX 82
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
LSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 83 XXXXXXXXXXLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 142
Query 161 KLRKRLLRDADDLQKRLAVYQ 181
KLRKRLLRDADDLQKRLAVYQ
Sbjct 143 KLRKRLLRDADDLQKRLAVYQ 163
>1nfo_A A APOLIPOPROTEIN E2
Length=191
Score = 225 bits (573), Expect = 2e-72, Method: Compositional matrix adjust.
Identities = 129/141 (91%), Positives = 129/141 (91%), Gaps = 0/141 (0%)
Query 41 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQL 100
GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQ
Sbjct 23 GQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQX 82
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
RLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 83 XXXXXXXXXRLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 142
Query 161 KLRKRLLRDADDLQKRLAVYQ 181
KLRKRLLRDAD LQK LAVYQ
Sbjct 143 KLRKRLLRDADALQKCLAVYQ 163
>8ax8_A A Maltose/maltodextrin-binding periplasmic protein,Apolipoprotein
E
Length=675
Score = 234 bits (598), Expect = 1e-70, Method: Compositional matrix adjust.
Identities = 134/140 (96%), Positives = 134/140 (96%), Gaps = 0/140 (0%)
Query 42 QRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT 101
QRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT
Sbjct 400 QRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLT 459
Query 102 PVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLRK 161
P RARLSKELQAAQARLGADMEDV GRLVQYRGEVQAMLGQSTEELRVRLASHLRK
Sbjct 460 PXXXXXRARLSKELQAAQARLGADMEDVRGRLVQYRGEVQAMLGQSTEELRVRLASHLRK 519
Query 162 LRKRLLRDADDLQKRLAVYQ 181
LRKRLLRDADDLQKRLAVYQ
Sbjct 520 LRKRLLRDADDLQKRLAVYQ 539
>6v7m_B B Apolipoprotein E
Length=83
Score = 164 bits (415), Expect = 4e-50, Method: Compositional matrix adjust.
Identities = 83/83 (100%), Positives = 83/83 (100%), Gaps = 0/83 (0%)
Query 101 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 160
TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR
Sbjct 1 TPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASHLR 60
Query 161 KLRKRLLRDADDLQKRLAVYQAG 183
KLRKRLLRDADDLQKRLAVYQAG
Sbjct 61 KLRKRLLRDADDLQKRLAVYQAG 83
>6v7m_A A Apolipoprotein E
Length=100
Score = 128 bits (321), Expect = 8e-36, Method: Compositional matrix adjust.
Identities = 64/64 (100%), Positives = 64/64 (100%), Gaps = 0/64 (0%)
Query 36 TEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSE 95
TEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSE
Sbjct 36 TEWQSGQRWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSE 95
Query 96 LEEQ 99
LEEQ
Sbjct 96 LEEQ 99
>1oef_A A APOLIPOPROTEIN E
Length=24
Score = 52.8 bits (125), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 24/24 (100%), Positives = 24/24 (100%), Gaps = 0/24 (0%)
Query 281 SWFEPLVEDMQRQWAGLVEKVQAA 304
SWFEPLVEDMQRQWAGLVEKVQAA
Sbjct 1 SWFEPLVEDMQRQWAGLVEKVQAA 24
>1oeg_A A APOLIPOPROTEIN E
Length=23
Score = 49.3 bits (116), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 23/23 (100%), Positives = 23/23 (100%), Gaps = 0/23 (0%)
Query 285 PLVEDMQRQWAGLVEKVQAAVGT 307
PLVEDMQRQWAGLVEKVQAAVGT
Sbjct 1 PLVEDMQRQWAGLVEKVQAAVGT 23
>6cm1_C C Apolipoprotein A-I
Length=211
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 49/174 (28%), Positives = 87/174 (50%), Gaps = 2/174 (1%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 4 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQ 63
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
++ +L +K+ + + ++++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 64 KVEPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 123
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 124 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 176
>6cm1_B B Apolipoprotein A-I
Length=211
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 49/174 (28%), Positives = 87/174 (50%), Gaps = 2/174 (1%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 4 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQ 63
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
++ +L +K+ + + ++++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 64 KVEPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 123
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 124 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 176
>6clz_C C Apolipoprotein A-I
Length=211
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 49/174 (28%), Positives = 87/174 (50%), Gaps = 2/174 (1%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 4 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQ 63
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
++ +L +K+ + + ++++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 64 KVEPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 123
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 124 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 176
>6clz_B B Apolipoprotein A-I
Length=211
Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 49/174 (28%), Positives = 87/174 (50%), Gaps = 2/174 (1%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 4 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQ 63
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
++ +L +K+ + + ++++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 64 KVEPYLDDFQKKWQEEMELYRQKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 123
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 124 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 176
>2kny_A A LRP-1, linker, Apo-E
Length=80
Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 19/19 (100%), Positives = 19/19 (100%), Gaps = 0/19 (0%)
Query 149 EELRVRLASHLRKLRKRLL 167
EELRVRLASHLRKLRKRLL
Sbjct 62 EELRVRLASHLRKLRKRLL 80
>3s84_B B Apolipoprotein A-IV
Length=273
Score = 42.4 bits (98), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 46/211 (22%), Positives = 94/211 (45%), Gaps = 18/211 (9%)
Query 96 LEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRL 155
L+E++ EE RARL ++G ++ ++ RL Y +++ + E+LR +L
Sbjct 16 LKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQVNTQAEQLRRQL 75
Query 156 ASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGS 215
+ +++ + L +AD LQ L + + ++ + ++ RL P ++ +V+
Sbjct 76 TPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVE 135
Query 216 LAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAF 275
+ L AQ E+L ++E + + + +E+K A + A EE
Sbjct 136 ELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELK---ARISASAEE------------ 180
Query 276 QARLKSWFEPLVEDMQRQWAGLVEKVQAAVG 306
L+ PL ED++ G E +Q ++
Sbjct 181 ---LRQRLAPLAEDVRGNLRGNTEGLQKSLA 208
Score = 42.0 bits (97), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 47/178 (26%), Positives = 83/178 (47%), Gaps = 29/178 (16%)
Query 50 RFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRA 109
+ D LR +Q E ++L + TQ ++ ++L Y +E L A+ +A
Sbjct 41 KIGDNLRELQQRLEPYADQLRTQVNTQ-----AEQLRRQLTPYAQRMERVLRENADSLQA 95
Query 110 RLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASH----------- 158
L +A++ ++E++ GRL Y E + + Q+ EELR LA +
Sbjct 96 SLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQ 155
Query 159 LRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVE--QGRVRAATVG 214
L L ++ ++A++L+ R++ A A E +R+RL PL E +G +R T G
Sbjct 156 LEGLTFQMKKNAEELKARIS---ASAEE--------LRQRLAPLAEDVRGNLRGNTEG 202
Score = 32.0 bits (71), Expect = 7.6, Method: Compositional matrix adjust.
Identities = 43/193 (22%), Positives = 81/193 (42%), Gaps = 33/193 (17%)
Query 145 GQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVE 204
+ +E+L+ + L +LR RLL A+++ +++ L +++RL P +
Sbjct 10 AKDSEKLKEEIGKELEELRARLLPHANEVSQKIG-----------DNLRELQQRLEPYAD 58
Query 205 QGRVRAATVGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVK----EQVAEVRAK 260
Q R + T + L AQ LR + + + R DE+K + V E++ +
Sbjct 59 QLRTQVNTQAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGR 118
Query 261 LEEQAQQIRLQAEAFQARLKSWFEPLVEDMQ----RQWAGLV-------EKVQAAVGTSA 309
L A + +++ + L+ P +D Q Q GL E+++A + SA
Sbjct 119 LTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASA 178
Query 310 -------APVPSD 315
AP+ D
Sbjct 179 EELRQRLAPLAED 191
Score = 32.0 bits (71), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 42/134 (31%), Positives = 58/134 (43%), Gaps = 24/134 (18%)
Query 49 GRFWDYLRWVQTLSEQVQEELLSS-----QVTQE--------LRALMDETMKELKAYKS- 94
GR Y + +Q EEL S Q TQE L M + +ELKA S
Sbjct 117 GRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISA 176
Query 95 ---ELEEQLTPVAEETRARL---SKELQAAQARLGADM----EDVCGRLVQYRGEVQAML 144
EL ++L P+AE+ R L ++ LQ + A LG + E+ R+ Y L
Sbjct 177 SAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKAL 236
Query 145 GQSTEELRVRLASH 158
Q E+LR +L H
Sbjct 237 VQQMEQLRQKLGPH 250
>3s84_A A Apolipoprotein A-IV
Length=273
Score = 42.4 bits (98), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 46/211 (22%), Positives = 94/211 (45%), Gaps = 18/211 (9%)
Query 96 LEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRL 155
L+E++ EE RARL ++G ++ ++ RL Y +++ + E+LR +L
Sbjct 16 LKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQVNTQAEQLRRQL 75
Query 156 ASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAATVGS 215
+ +++ + L +AD LQ L + + ++ + ++ RL P ++ +V+
Sbjct 76 TPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVE 135
Query 216 LAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQQIRLQAEAF 275
+ L AQ E+L ++E + + + +E+K A + A EE
Sbjct 136 ELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELK---ARISASAEE------------ 180
Query 276 QARLKSWFEPLVEDMQRQWAGLVEKVQAAVG 306
L+ PL ED++ G E +Q ++
Sbjct 181 ---LRQRLAPLAEDVRGNLRGNTEGLQKSLA 208
Score = 42.0 bits (97), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 47/178 (26%), Positives = 83/178 (47%), Gaps = 29/178 (16%)
Query 50 RFWDYLRWVQTLSEQVQEELLSSQVTQELRALMDETMKELKAYKSELEEQLTPVAEETRA 109
+ D LR +Q E ++L + TQ ++ ++L Y +E L A+ +A
Sbjct 41 KIGDNLRELQQRLEPYADQLRTQVNTQ-----AEQLRRQLTPYAQRMERVLRENADSLQA 95
Query 110 RLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRVRLASH----------- 158
L +A++ ++E++ GRL Y E + + Q+ EELR LA +
Sbjct 96 SLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQ 155
Query 159 LRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVE--QGRVRAATVG 214
L L ++ ++A++L+ R++ A A E +R+RL PL E +G +R T G
Sbjct 156 LEGLTFQMKKNAEELKARIS---ASAEE--------LRQRLAPLAEDVRGNLRGNTEG 202
Score = 32.0 bits (71), Expect = 9.1, Method: Compositional matrix adjust.
Identities = 42/134 (31%), Positives = 58/134 (43%), Gaps = 24/134 (18%)
Query 49 GRFWDYLRWVQTLSEQVQEELLSS-----QVTQE--------LRALMDETMKELKAYKS- 94
GR Y + +Q EEL S Q TQE L M + +ELKA S
Sbjct 117 GRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISA 176
Query 95 ---ELEEQLTPVAEETRARL---SKELQAAQARLGADM----EDVCGRLVQYRGEVQAML 144
EL ++L P+AE+ R L ++ LQ + A LG + E+ R+ Y L
Sbjct 177 SAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKAL 236
Query 145 GQSTEELRVRLASH 158
Q E+LR +L H
Sbjct 237 VQQMEQLRQKLGPH 250
>6pts_B C Apolipoprotein A-I
Length=198
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 15 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 73
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 74 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 112
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 113 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 165
>6pts_A A Apolipoprotein A-I
Length=198
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 15 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 73
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 74 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 112
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 113 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 165
>6ptw_A A Apolipoprotein A-I
Length=198
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 15 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 73
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 74 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 112
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 113 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 165
>6ptw_B C Apolipoprotein A-I
Length=198
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 15 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 73
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 74 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 112
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 113 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 165
>6cc9_A A Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>6cc9_C C Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>6w4e_A A Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>6w4f_B D Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>6w4f_A A Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>4v6m_F A1 Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 15 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 73
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 74 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 112
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 113 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 165
>4v6m_E A0 Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 15 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 73
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 74 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 112
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 113 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 165
>6ccx_C C Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>6ccx_A A Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>6cch_C C Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>6cch_A A Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>6w4e_B D Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>2msd_A A Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>2mse_A A Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>2mse_B C Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>2msd_B C Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>2msc_A A Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>2msc_B C Apolipoprotein A-I
Length=200
Score = 40.0 bits (92), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>3k2s_B B Apolipoprotein A-I
Length=243
Score = 40.4 bits (93), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 58 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 116
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 117 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 155
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 156 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 208
>3k2s_A A Apolipoprotein A-I
Length=243
Score = 40.4 bits (93), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 58 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 116
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 117 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 155
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 156 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 208
>1av1_A A APOLIPOPROTEIN A-I
Length=201
Score = 40.0 bits (92), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 16 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 74
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 75 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 113
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 114 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 166
>1av1_B B APOLIPOPROTEIN A-I
Length=201
Score = 40.0 bits (92), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 16 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 74
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 75 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 113
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 114 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 166
>1av1_D D APOLIPOPROTEIN A-I
Length=201
Score = 40.0 bits (92), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 16 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 74
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 75 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 113
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 114 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 166
>1av1_C C APOLIPOPROTEIN A-I
Length=201
Score = 40.0 bits (92), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 16 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 74
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 75 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 113
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 114 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 166
>7rsc_C D Apolipoprotein A-I
Length=200
Score = 38.9 bits (89), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>7rse_D E Apolipoprotein A-I
Length=200
Score = 38.9 bits (89), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>7rse_C D Apolipoprotein A-I
Length=200
Score = 38.9 bits (89), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>7rsc_D E Apolipoprotein A-I
Length=200
Score = 38.9 bits (89), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 47/174 (27%), Positives = 77/174 (44%), Gaps = 24/174 (14%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 17 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYR- 75
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRA-AT 212
+++ +A +EGA + L ++E+L PL E+ R RA A
Sbjct 76 ---------------------QKVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAH 114
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQVAEVRAKLEEQAQ 266
V +L L + +RL AR+E + RL E + E + L E+A+
Sbjct 115 VDALRTH-LAPYSDELRQRLAARLEALKENGGARLAEYHAKATEHLSTLSEKAK 167
>2n5e_B B Apolipoprotein A-I
Length=167
Score = 38.5 bits (88), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 41/139 (29%), Positives = 61/139 (44%), Gaps = 28/139 (20%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAM---------- 143
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q
Sbjct 4 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQ 63
Query 144 ----LGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVY------QAGAR-----EGA 188
LG EE+R R +H+ LR L +D+L++RLA GAR A
Sbjct 64 KVEPLG---EEMRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKA 120
Query 189 ERGLSAIRERLGPLVEQGR 207
LS + E+ P +E R
Sbjct 121 TEHLSTLSEKAKPALEDLR 139
>2n5e_A A Apolipoprotein A-I
Length=167
Score = 38.5 bits (88), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 41/139 (29%), Positives = 61/139 (44%), Gaps = 28/139 (20%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAM---------- 143
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q
Sbjct 4 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQ 63
Query 144 ----LGQSTEELRVRLASHLRKLRKRLLRDADDLQKRLAVY------QAGAR-----EGA 188
LG EE+R R +H+ LR L +D+L++RLA GAR A
Sbjct 64 KVEPLG---EEMRDRARAHVDALRTHLAPYSDELRQRLAARLEALKENGGARLAEYHAKA 120
Query 189 ERGLSAIRERLGPLVEQGR 207
LS + E+ P +E R
Sbjct 121 TEHLSTLSEKAKPALEDLR 139
>3r2p_A A Apolipoprotein A-I
Length=185
Score = 37.0 bits (84), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 31/118 (26%), Positives = 57/118 (48%), Gaps = 0/118 (0%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L EQL PV +E L KE + + + D+E+V ++ Y + Q + E R
Sbjct 59 SKLREQLGPVTQEFWDNLEKETEGLRQEMSKDLEEVKAKVQPYLDDFQKKWQEEMELYRQ 118
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAA 211
++ +L++ + +LQ++L+ R+ A + A+R L P ++ R R A
Sbjct 119 KVEPLRAELQEGARQKLHELQEKLSPLGEEMRDRARAHVDALRTHLAPYSDELRQRLA 176
>2lem_A A Apolipoprotein A-I
Length=216
Score = 33.9 bits (76), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 34/162 (21%), Positives = 72/162 (44%), Gaps = 4/162 (2%)
Query 94 SELEEQLTPVAEETRARLSKELQAAQARLGADMEDVCGRLVQYRGEVQAMLGQSTEELRV 153
S+L+E+L P+ + L KE + + D+E+V ++ Y E Q + E R
Sbjct 57 SQLQERLGPLTRDFWDNLEKETDWVRQEMNKDLEEVKQKVQPYLDEFQKKWKEDVELYRQ 116
Query 154 RLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGLSAIRERLGPLVEQGRVRAAT- 212
+ + +L++ + +LQ RL+ R+ + ++R +L P EQ R A
Sbjct 117 KASPQGAELQESARQKLQELQGRLSPVAEEFRDRMRTHVDSLRTQLAPHSEQMRESLAQR 176
Query 213 VGSLAGQPLQERAQAWGERLRARMEEMGSRTRDRLDEVKEQV 254
+ L P + ++ ++ +G + R L++++ +
Sbjct 177 LAELKSNPT---LNEYHSSAKSHLKSLGEKARPALEDLRHSL 215
Lambda K H a alpha
0.315 0.128 0.360 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 29880958430
Database: unitmol_20241002.fasta
Posted date: Oct 3, 2024 2:33 PM
Number of letters in database: 253,696,794
Number of sequences in database: 877,468
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40