[Multiple Alignment(many alignments)]
[Alignment Bar(many alignments)]
[show plain BLAST file]
BLASTP 2.11.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: unitmol_20240501.fasta
835,512 sequences; 240,313,072 total letters
Query= sp|O15455|TLR3_HUMAN Toll-like receptor 3 OS=Homo sapiens OX=9606
GN=TLR3 PE=1 SV=1
Length=904
Score E
Sequences producing significant alignments: (Bits) Value
7c76_A A Toll-like receptor 3 1384 0.0
2a0z_A A Toll-like receptor 3 1347 0.0
7wv3_A A Toll-like receptor 3 1339 0.0
3ulv_A A Toll-like receptor 3 1339 0.0
7wv3_B B Toll-like receptor 3 1339 0.0
7wv3_C C Toll-like receptor 3 1339 0.0
7wv3_D D Toll-like receptor 3 1339 0.0
5gs0_D B Toll-like receptor 3 1328 0.0
5gs0_A A Toll-like receptor 3 1328 0.0
3ulu_A A Toll-like receptor 3 1320 0.0
7wv4_C C Toll-like receptor 3 1320 0.0
7wvf_A A Toll-like receptor 3 1320 0.0
7wv4_B B Toll-like receptor 3 1320 0.0
7wv4_A A Toll-like receptor 3 1320 0.0
7wv5_A A Toll-like receptor 3 1320 0.0
7wvf_B B Toll-like receptor 3 1320 0.0
7wv4_D D Toll-like receptor 3 1320 0.0
7wv5_B B Toll-like receptor 3 1320 0.0
7wvj_B B Toll-like receptor 3 1314 0.0
7wvj_A A Toll-like receptor 3 1314 0.0
7wve_A A Toll-like receptor 3 1313 0.0
7wve_B B Toll-like receptor 3 1313 0.0
1ziw_A A Toll-like receptor 3 1254 0.0
7c77_A A Toll-like receptor 3 1042 0.0
7da7_B B Toll-like receptor 3 1016 0.0
7da7_A A Toll-like receptor 3 1016 0.0
7das_A A Toll-like receptor 3 1015 0.0
7wm4_B D Toll-like receptor 3 1013 0.0
7das_B B Toll-like receptor 3 1013 0.0
3ciy_D B Toll-like receptor 3 1013 0.0
7wm4_D F Toll-like receptor 3 1013 0.0
7wm4_A C Toll-like receptor 3 1001 0.0
3ciy_C A Toll-like receptor 3 1001 0.0
7wm4_C E Toll-like receptor 3 1001 0.0
3cig_A A Toll-like receptor 3 999 0.0
4r6f_A A Leucine rich repeat DLRR_I 181 3e-49
3j0a_A A Toll-like receptor 5 152 2e-36
7wrq_A A Insulin-like growth factor-binding protein complex acid ... 136 4e-32
4r6g_A A leucine rich repeats DLRR_K 132 2e-31
4r6j_C C Lucine rich repeats DLRR_H 124 2e-30
4r6j_B B Lucine rich repeats DLRR_H 124 2e-30
4r6j_A A Lucine rich repeats DLRR_H 124 2e-30
4r6j_D D Lucine rich repeats DLRR_H 124 2e-30
8ar1_A A Toll-like receptor 3 102 3e-25
4z0c_B D Toll-like receptor 13 115 6e-25
4z0c_A A Toll-like receptor 13 115 6e-25
5zln_B B Toll-like receptor 9 112 4e-24
5zln_A A Toll-like receptor 9 112 5e-24
3b2d_B B CD180 antigen 111 7e-24
3b2d_A A CD180 antigen 111 7e-24
4li1_B A Leucine-rich repeat-containing G-protein coupled receptor 4 108 2e-23
4li1_A B Leucine-rich repeat-containing G-protein coupled receptor 4 108 2e-23
5a5c_B B LRRTM 103 2e-22
5a5c_C C LRRTM 103 2e-22
5a5c_D D LRRTM 103 2e-22
5a5c_A A LRRTM 103 3e-22
3rg1_G J CD180 molecule 105 4e-22
3rg1_H N CD180 molecule 105 4e-22
3rg1_E B CD180 molecule 105 4e-22
3rg1_F F CD180 molecule 105 4e-22
4li2_A A Leucine-rich repeat-containing G-protein coupled receptor 4 103 4e-22
3rg1_D M CD180 molecule 105 6e-22
3rg1_A A CD180 molecule 105 7e-22
3rg1_B E CD180 molecule 105 7e-22
4kt1_A A Leucine-rich repeat-containing G-protein coupled receptor 4 103 9e-22
3fxi_A A Toll-like receptor 4 103 2e-21
3fxi_B B Toll-like receptor 4 103 2e-21
4g8a_A A Toll-like receptor 4 103 3e-21
4g8a_B B Toll-like receptor 4 103 3e-21
5zsm_A B Toll-like receptor 7 102 6e-21
3j0a_B B Toll-like receptor 5 102 7e-21
5zsl_A B Toll-like receptor 7 102 8e-21
5zsm_B A Toll-like receptor 7 102 9e-21
3wpf_A A Toll-like receptor 9 101 1e-20
5gmf_A A Toll-like receptor 7 100 2e-20
5gmf_C C Toll-like receptor 7 100 2e-20
5gmf_D D Toll-like receptor 7 100 2e-20
5gmf_B B Toll-like receptor 7 100 2e-20
6lvx_B B Toll-like receptor 7 100 3e-20
6lvy_B B Toll-like receptor 7 100 3e-20
6lvx_A A Toll-like receptor 7 100 3e-20
6lvy_A A Toll-like receptor 7 100 3e-20
5gmh_B B Toll-like receptor 7 100 3e-20
8ttz_A A Toll-like receptor 7 100 3e-20
8ttz_B B Toll-like receptor 7 100 3e-20
5gmh_A A Toll-like receptor 7 100 3e-20
5zsi_B A Toll-like receptor 7 100 3e-20
5zsj_B B Toll-like receptor 7 100 3e-20
5zsj_A A Toll-like receptor 7 100 3e-20
5zsi_A B Toll-like receptor 7 100 3e-20
5zsf_A B Toll-like receptor 7 100 3e-20
5zsn_B A Toll-like receptor 7 100 3e-20
5zsn_A B Toll-like receptor 7 100 3e-20
5zsh_A B Toll-like receptor 7 100 3e-20
5zsh_B A Toll-like receptor 7 100 3e-20
5zsg_B A Toll-like receptor 7 100 3e-20
5zsg_A B Toll-like receptor 7 100 3e-20
6lw0_A B Toll-like receptor 7 100 3e-20
6lvz_B A Toll-like receptor 7 100 3e-20
6lvz_A B Toll-like receptor 7 100 3e-20
6lw0_B A Toll-like receptor 7 100 3e-20
5zsf_B A Toll-like receptor 7 100 3e-20
5zsb_B A Toll-like receptor 7 100 3e-20
5zsd_B A Toll-like receptor 7 100 3e-20
6if5_A B Toll-like receptor 7 100 3e-20
5zsl_B A Toll-like receptor 7 100 3e-20
5zsa_B A Toll-like receptor 7 100 3e-20
5zsc_A B Toll-like receptor 7 100 4e-20
5zse_A B Toll-like receptor 7 100 4e-20
5zsa_A B Toll-like receptor 7 100 4e-20
6if5_B A Toll-like receptor 7 99.4 6e-20
5zsb_A B Toll-like receptor 7 99.4 6e-20
5zse_B A Toll-like receptor 7 99.4 6e-20
5zsd_A B Toll-like receptor 7 99.4 6e-20
5zsc_B A Toll-like receptor 7 99.4 6e-20
2z63_A A Toll-like receptor 4, Variable lymphocyte receptor B 98.2 9e-20
3wpi_A A Toll-like receptor 9 98.6 1e-19
4qxe_A A Leucine-rich repeat-containing G-protein coupled recepto... 94.4 6e-19
3wpg_A A Toll-like receptor 9 96.3 7e-19
3wph_A A Toll-like receptor 9 95.5 1e-18
3wpd_A A Toll-like receptor 9 92.4 9e-18
3wpb_A A Toll-like receptor 9 92.4 9e-18
3wpc_B B Toll-like receptor 9 92.0 1e-17
5y3l_A A Toll-like receptor 9 91.7 1e-17
5y3j_B B Toll-like receptor 9 91.7 1e-17
5y3l_D B Toll-like receptor 9 91.7 1e-17
5y3k_A A Toll-like receptor 9 91.7 1e-17
5y3j_A A Toll-like receptor 9 91.7 1e-17
5y3k_D B Toll-like receptor 9 91.7 1e-17
3wpc_A A Toll-like receptor 9 91.7 2e-17
3zyi_A A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4 90.1 2e-17
7cyn_B B Toll-like receptor 7 90.5 5e-17
7cyn_A A Toll-like receptor 7 90.5 5e-17
6lw1_B B Toll-like receptor 7 89.4 8e-17
6lw1_A A Toll-like receptor 7 89.4 8e-17
8tty_A A Toll-like receptor 7 89.0 1e-16
8s9h_A A Toll-like receptor 7 89.0 1e-16
8s9h_B B Toll-like receptor 7 89.0 1e-16
8tty_B B Toll-like receptor 7 89.0 1e-16
5ijd_D B Toll-like receptor 4, Variable lymphocyte receptor B chi... 88.6 1e-16
5ijb_C B Toll-like receptor 4, Variable lymphocyte receptor B chi... 88.6 1e-16
7mlm_A A Toll-like receptor 4,Variable lymphocyte receptor B 88.6 1e-16
5gmg_B B Toll-like receptor 7 89.0 1e-16
5gmg_A A Toll-like receptor 7 89.0 1e-16
5ijb_A A Toll-like receptor 4, Variable lymphocyte receptor B chi... 88.2 1e-16
5ijd_A A Toll-like receptor 4, Variable lymphocyte receptor B chi... 88.2 1e-16
4u7l_A A Leucine-rich repeats and immunoglobulin-like domains pro... 87.4 1e-16
5ijc_C B Toll-like receptor 4,Variable lymphocyte receptor B 88.2 1e-16
3t6q_A A CD180 antigen 88.2 1e-16
3t6q_C B CD180 antigen 88.2 1e-16
6gff_I I Leucine-rich repeat-containing protein 32 87.8 2e-16
4r5d_A A Leucine rich repeat protein 86.3 3e-16
5y3m_A A Toll-like receptor 9 87.0 5e-16
3zyn_A A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B 83.2 8e-16
3zyn_B B LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B 83.2 1e-15
7ytp_A A Toll-like receptor 7 85.5 2e-15
7ytp_B B Toll-like receptor 7 85.5 2e-15
7b1c_A C Toll-like receptor 85.1 2e-15
5ijc_A A Toll-like receptor 4,Variable lymphocyte receptor B 84.7 2e-15
7b1c_B A Toll-like receptor 85.1 2e-15
7b1b_D B Toll-like receptor 85.1 2e-15
7b1c_E B Toll-like receptor 85.1 2e-15
7b1d_B C Toll-like receptor 84.7 2e-15
7b1b_A A Toll-like receptor 84.7 2e-15
7b1d_A B Toll-like receptor 84.7 2e-15
2o6q_A A Variable lymphocyte receptor A 80.9 2e-15
4lxs_A A Protein toll 84.3 3e-15
4lxr_A A Protein toll 84.0 4e-15
4pq8_A A DESIGNED PROTEIN OR465 80.5 4e-15
7e5b_A A Repebody (Rb-B7) 79.3 8e-15
7e5b_B B Repebody (Rb-B7) 79.3 8e-15
4qxf_A A Leucine-rich repeat-containing G-protein coupled recepto... 80.1 8e-15
4qxf_B B Leucine-rich repeat-containing G-protein coupled recepto... 79.7 9e-15
4psj_A A OR464 79.0 1e-14
3zyo_A A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B 80.1 2e-14
4r5c_A A Leucine rich repeat protein 78.6 2e-14
4po4_A A Lampetra planeri VLRC 76.6 3e-14
4po4_B B Lampetra planeri VLRC 76.6 3e-14
5y3m_F B Toll-like receptor 9 80.9 3e-14
5z8y_G G Leucine-rich repeat transmembrane neuronal protein 2 78.6 4e-14
5z8y_E E Leucine-rich repeat transmembrane neuronal protein 2 78.6 4e-14
5z8y_A A Leucine-rich repeat transmembrane neuronal protein 2 78.6 4e-14
5z8y_C C Leucine-rich repeat transmembrane neuronal protein 2 78.6 4e-14
5z8x_C C Leucine-rich repeat transmembrane neuronal protein 2 78.6 4e-14
5z8x_A A Leucine-rich repeat transmembrane neuronal protein 2 78.6 4e-14
5z8x_D D Leucine-rich repeat transmembrane neuronal protein 2 78.6 4e-14
5z8x_B B Leucine-rich repeat transmembrane neuronal protein 2 78.6 4e-14
3wo9_A A Variable lymphocyte receptor C 75.5 1e-13
2o6s_B B Variable lymphocyte receptor B 74.3 1e-13
2o6s_A A Variable lymphocyte receptor B 74.3 1e-13
3rfs_A A Internalin B, repeat modules, Variable lymphocyte recept... 75.5 2e-13
3rfs_B B Internalin B, repeat modules, Variable lymphocyte recept... 75.5 2e-13
4j4l_B B Internalin B,REPEAT MODULES,Variable lymphocyte receptor B 75.1 2e-13
4j4l_A A Internalin B,REPEAT MODULES,Variable lymphocyte receptor B 75.1 2e-13
8h6f_E Y Repebody (A6) 75.1 2e-13
7yco_B B Repebody (A6) 75.1 2e-13
8h6f_F Z Repebody (A6) 75.1 2e-13
8h6f_D X Repebody (A6) 75.1 2e-13
2z64_A A Toll-like receptor 4 77.8 3e-13
2mka_B B Toll-like receptor 3 68.2 3e-13
2mka_A A Toll-like receptor 3 68.2 3e-13
2mka_C C Toll-like receptor 3 68.2 3e-13
2mk9_B B Toll-like receptor 3 68.2 3e-13
2mk9_A A Toll-like receptor 3 68.2 3e-13
3vq1_C B Toll-like receptor 4 77.4 3e-13
3vq1_A A Toll-like receptor 4 77.4 3e-13
6htf_B B rF10 repebody 74.7 3e-13
5hdh_A A Toll-like receptor 8 77.4 4e-13
3vq2_A A Toll-like receptor 4 76.6 5e-13
3vq2_C B Toll-like receptor 4 76.6 5e-13
2id5_C C Leucine rich repeat neuronal 6A 76.3 5e-13
2id5_A A Leucine rich repeat neuronal 6A 76.3 6e-13
2v9s_A A SLIT HOMOLOG 2 PROTEIN N-PRODUCT 72.8 6e-13
2v9s_C C SLIT HOMOLOG 2 PROTEIN N-PRODUCT 72.8 6e-13
2v9s_D D SLIT HOMOLOG 2 PROTEIN N-PRODUCT 72.8 6e-13
2v9s_B B SLIT HOMOLOG 2 PROTEIN N-PRODUCT 72.8 6e-13
6lbx_A A Repebody (Rb-H2) 73.9 6e-13
2id5_B B Leucine rich repeat neuronal 6A 75.9 7e-13
4oqt_A A Leucine-rich repeat and immunoglobulin-like domain-conta... 75.9 8e-13
2v9t_B B SLIT HOMOLOG 2 PROTEIN N-PRODUCT 72.4 9e-13
5z15_B B Toll-like receptor 8 76.3 1e-12
3wpe_A A Toll-like receptor 9 75.9 1e-12
6zjz_B B Toll-like receptor 8 75.9 1e-12
3wn4_A A Toll-like receptor 8 75.5 2e-12
3kj4_F D Reticulon-4 receptor 72.4 2e-12
3kj4_C A Reticulon-4 receptor 72.4 2e-12
3w3k_B B Toll-like receptor 8 75.1 2e-12
3w3k_A A Toll-like receptor 8 75.1 2e-12
4ufr_C C LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 74.3 2e-12
5awc_B B Toll-like receptor 8 75.1 2e-12
5awd_A A Toll-like receptor 8 75.1 2e-12
4ufr_A A LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 74.3 2e-12
4r09_A A Toll-like receptor 8 75.1 2e-12
3w3j_B B Toll-like receptor 8 74.7 2e-12
4bst_B B LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 74.3 3e-12
6wml_A A Toll-like receptor 8 74.7 3e-12
4r08_D D Toll-like receptor 8 74.7 3e-12
5az5_D D Toll-like receptor 8 74.7 3e-12
4bss_B B LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 74.3 3e-12
5awc_A A Toll-like receptor 8 74.7 3e-12
4r09_C C Toll-like receptor 8 74.7 3e-12
5awb_A A Toll-like receptor 8 74.7 3e-12
4qbz_A A Toll-like receptor 8 74.7 3e-12
4kng_A A Leucine-rich repeat-containing G-protein coupled receptor 5 74.3 3e-12
4bst_A A LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 74.3 3e-12
4r08_A A Toll-like receptor 8 74.7 3e-12
4ufs_A A LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 73.9 3e-12
3w3l_A A Toll-like receptor 8 74.7 3e-12
3w3l_D D Toll-like receptor 8 74.7 3e-12
6wml_B B Toll-like receptor 8 74.7 3e-12
3w3l_B B Toll-like receptor 8 74.7 3e-12
3w3m_A A Toll-like receptor 8 74.7 3e-12
3w3l_C C Toll-like receptor 8 74.7 3e-12
3w3n_A A Toll-like receptor 8 74.7 3e-12
4bsu_F F LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 74.3 3e-12
4bsu_E E LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 73.9 3e-12
4bsu_A A LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 73.9 3e-12
4bss_A A LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 73.9 3e-12
4bss_F F LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 73.9 3e-12
4bss_E E LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 73.9 3e-12
3w3j_A A Toll-like receptor 8 74.7 3e-12
4r09_D D Toll-like receptor 8 74.7 3e-12
4kng_B B Leucine-rich repeat-containing G-protein coupled receptor 5 73.9 3e-12
5uei_A A O13 71.2 3e-12
2id5_D D Leucine rich repeat neuronal 6A 73.6 3e-12
3w3n_B B Toll-like receptor 8 74.3 3e-12
4r07_A A Toll-like receptor 8 74.3 4e-12
4bsu_B B LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 73.9 4e-12
4bsr_A A LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 73.9 4e-12
5az5_A A Toll-like receptor 8 74.3 4e-12
5az5_C C Toll-like receptor 8 74.3 4e-12
5az5_B B Toll-like receptor 8 74.3 4e-12
4qc0_A A Toll-like receptor 8 74.3 4e-12
4bsr_B B LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5 73.6 4e-12
4r08_B B Toll-like receptor 8 73.9 4e-12
5uf1_B A O13 70.9 5e-12
5uf1_A B O13 70.9 5e-12
5uf4_A A O13 70.9 5e-12
5uf4_B B O13 70.9 5e-12
5uf4_C C O13 70.9 5e-12
5b4p_A A repebody 70.9 5e-12
4r6a_A A Toll-like receptor 8 73.6 6e-12
4r07_B B Toll-like receptor 8 73.6 6e-12
5z14_B B Toll-like receptor 8 73.6 6e-12
5z15_A A Toll-like receptor 8 73.6 7e-12
7ytx_B B Toll-like receptor 8 73.6 7e-12
3w3g_A A Toll-like receptor 8 73.6 7e-12
4r6a_B B Toll-like receptor 8 73.2 7e-12
4r0a_A A Toll-like receptor 8 73.2 8e-12
4qc0_B B Toll-like receptor 8 73.2 8e-12
7ytx_A A Toll-like receptor 8 73.2 8e-12
5b4p_C C repebody 70.5 8e-12
5wyx_A A Toll-like receptor 8 73.2 8e-12
5wyz_A A Toll-like receptor 8 73.2 8e-12
4r07_D D Toll-like receptor 8 73.2 8e-12
3w3g_B B Toll-like receptor 8 73.2 9e-12
5ufb_A A Tn4-22 69.7 9e-12
5ufc_A A Tn4-22 69.7 9e-12
5ufc_C C Tn4-22 69.7 9e-12
5ufc_B B Tn4-22 69.7 9e-12
6v9u_B B Toll-like receptor 8 73.2 9e-12
7rc9_B B Toll-like receptor 8 73.2 9e-12
7rc9_A A Toll-like receptor 8 73.2 9e-12
6bxa_A A Toll-like receptor 5b, Variable lymphocyte receptor B ch... 72.0 1e-11
5wyz_B B Toll-like receptor 8 72.8 1e-11
5gy2_A A Tlr5b protein,Variable lymphocyte receptor B 72.0 1e-11
6bxc_B B Toll-like receptor 5b, Variable lymphocyte receptor B ch... 72.0 1e-11
5gy2_C B Tlr5b protein,Variable lymphocyte receptor B 72.0 1e-11
3v47_A A Toll-like receptor 5b and variable lymphocyte receptor B... 72.0 1e-11
6bxa_B B Toll-like receptor 5b, Variable lymphocyte receptor B ch... 72.0 1e-11
6bxc_A A Toll-like receptor 5b, Variable lymphocyte receptor B ch... 72.0 1e-11
3v47_B B Toll-like receptor 5b and variable lymphocyte receptor B... 72.0 1e-11
7r52_B B Toll-like receptor 8 72.8 1e-11
6v9u_A A Toll-like receptor 8 72.8 1e-11
5z14_A A Toll-like receptor 8 72.8 1e-11
8pfi_B B Toll-like receptor 8 72.8 1e-11
3zyj_C C LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C 71.6 1e-11
3zyj_A A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C 71.6 1e-11
3ul9_A A Toll-like receptor 4, Variable lymphocyte receptor B 70.1 1e-11
3ul8_A A Toll-like receptor 4, Variable lymphocyte receptor B 69.7 1e-11
7r53_B B Toll-like receptor 8 72.4 2e-11
6kya_A A Toll-like receptor 8 72.4 2e-11
8pfi_A A Toll-like receptor 8 72.4 2e-11
7r52_A A Toll-like receptor 8 72.4 2e-11
7crf_B B Toll-like receptor 8 72.4 2e-11
5awa_A A Toll-like receptor 8 72.0 2e-11
2z65_B B Toll-like receptor 4, Variable lymphocyte receptor B 69.7 2e-11
2z62_A A Toll-like receptor 4, Variable lymphocyte receptor B 69.7 2e-11
2z65_A A Toll-like receptor 4, Variable lymphocyte receptor B 69.7 2e-11
7nuw_A A Toll-like receptor 1 67.0 2e-11
3ula_C C Toll-like receptor 4, Variable lymphocyte receptor B 69.3 2e-11
3ula_A A Toll-like receptor 4, Variable lymphocyte receptor B 69.3 2e-11
5o0o_H H Reticulon-4 receptor 70.1 2e-11
7nux_A A Toll-like receptor 1 66.6 2e-11
5o0o_G G Reticulon-4 receptor 70.1 2e-11
5o0o_B B Reticulon-4 receptor 70.1 2e-11
5o0m_A A Reticulon-4 receptor 70.1 2e-11
5o0o_D D Reticulon-4 receptor 70.1 2e-11
5o0k_B B Reticulon-4 receptor 70.1 2e-11
5gs2_D B repebody 69.3 2e-11
5o0o_C C Reticulon-4 receptor 70.1 2e-11
5o0o_A A Reticulon-4 receptor 70.1 2e-11
5o0n_A A Reticulon-4 receptor 70.1 2e-11
5o0m_B B Reticulon-4 receptor 70.1 2e-11
5o0q_C C Reticulon-4 receptor 70.1 2e-11
3ul7_A A Toll-like receptor 4, Variable lymphocyte receptor B 69.3 2e-11
5o0q_A A Reticulon-4 receptor 70.1 2e-11
3rfj_A A Internalin B, repeat modules, Variable lymphocyte receptor 69.3 2e-11
5o0o_F F Reticulon-4 receptor 70.1 2e-11
5o0k_A A Reticulon-4 receptor 70.1 2e-11
5o0l_A A Reticulon-4 receptor 70.1 2e-11
5o0p_B B Reticulon-4 receptor 70.1 2e-11
5o0r_A A Reticulon-4 receptor 70.1 2e-11
5o0o_E E Reticulon-4 receptor 69.7 2e-11
5o0l_B B Reticulon-4 receptor 69.7 2e-11
5o0q_D D Reticulon-4 receptor 70.1 2e-11
5o0q_B B Reticulon-4 receptor 70.1 2e-11
5o0p_A A Reticulon-4 receptor 70.1 2e-11
7nt7_A A Toll-like receptor 1 66.6 3e-11
7r86_B B Reticulon-4 receptor 68.9 3e-11
5wyx_B B Toll-like receptor 8 71.6 3e-11
5o0r_B B Reticulon-4 receptor 69.7 3e-11
1fyv_A A TOLL-LIKE RECEPTOR 1 66.6 3e-11
4r07_C C Toll-like receptor 8 71.2 3e-11
7r86_A A Reticulon-4 receptor 68.9 3e-11
5awc_C C Toll-like receptor 8 71.2 4e-11
4qdh_A A Variable lymphocyte receptor B, Toll-like receptor 9 chi... 70.1 4e-11
4r08_C C Toll-like receptor 8 70.9 4e-11
6ty5_A A Toll-like receptor 8 70.9 4e-11
1xcd_A A Decorin 68.9 5e-11
1xec_B B Decorin 68.9 5e-11
1xec_A A Decorin 68.9 5e-11
4qdh_B B Variable lymphocyte receptor B, Toll-like receptor 9 chi... 69.7 5e-11
1xku_A A Decorin 68.9 5e-11
5lfn_C C Chondroadherin 68.9 5e-11
5lfn_B B Chondroadherin 68.9 5e-11
5lfn_A A Chondroadherin 68.9 5e-11
4uip_B B REPEBODY (RAC1) 67.4 6e-11
6gff_J J Leucine-rich repeat-containing protein 32 70.1 6e-11
5lfn_D D Chondroadherin 68.9 6e-11
7crf_A A Toll-like receptor 8 70.5 6e-11
5mx1_B B Chondroadherin 68.9 6e-11
5mx1_A A Chondroadherin 68.6 7e-11
3m19_A A Variable lymphocyte receptor A diversity region 67.0 9e-11
3m19_B B Variable lymphocyte receptor A diversity region 67.0 9e-11
2z66_A A Variable lymphocyte receptor B, Toll-like receptor 4 67.8 1e-10
2z66_B B Variable lymphocyte receptor B, Toll-like receptor 4 67.8 1e-10
2z66_D D Variable lymphocyte receptor B, Toll-like receptor 4 67.8 1e-10
2z66_C C Variable lymphocyte receptor B, Toll-like receptor 4 67.8 1e-10
6bxd_A A Variable Lymphocyte Receptor 2 65.9 1e-10
6bxa_D D Variable Lymphocyte Receptor 2 65.9 1e-10
6bxa_C C Variable Lymphocyte Receptor 2 65.9 1e-10
4bv4_C R PROTEIN TOLL, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA 68.6 1e-10
3m18_A A Variable lymphocyte receptor A diversity region 66.6 1e-10
4qbz_B B Toll-like receptor 8 68.9 2e-10
6zjz_A A Toll-like receptor 8 68.9 2e-10
5awc_D D Toll-like receptor 8 68.6 2e-10
4r09_B B Toll-like receptor 8 68.6 2e-10
2j67_B B TOLL LIKE RECEPTOR 10 63.9 2e-10
7r53_A A Toll-like receptor 8 68.2 3e-10
6ka7_A A repebody 65.5 3e-10
4arr_B B TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA 65.5 4e-10
4arn_D D TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA 65.5 4e-10
4arr_A A TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA 65.5 4e-10
4arn_B B TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA 65.5 4e-10
4arn_C C TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA 65.5 4e-10
4c2b_D D PLATELET GLYCOPROTEIN IB ALPHA CHAIN 65.5 4e-10
4arn_A A TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA 65.5 4e-10
6ty5_B B Toll-like receptor 8 67.8 4e-10
4om7_B B Toll-like receptor 6 63.2 5e-10
4om7_A A Toll-like receptor 6 63.2 5e-10
1p8t_A A Reticulon 4 receptor 65.5 5e-10
1ozn_A A Reticulon 4 receptor 65.5 5e-10
6kya_B B Toll-like receptor 8 67.4 5e-10
4c2b_F F PLATELET GLYCOPROTEIN IB ALPHA CHAIN 65.5 5e-10
4c2b_B B PLATELET GLYCOPROTEIN IB ALPHA CHAIN 65.5 5e-10
3p72_A A Platelet glycoprotein Ib alpha chain 64.7 6e-10
4c2b_H H PLATELET GLYCOPROTEIN IB ALPHA CHAIN 65.1 6e-10
4cnc_B B TROPHOBLAST GLYCOPROTEIN 65.1 6e-10
4c2a_B B PLATELET GLYCOPROTEIN IB ALPHA CHAIN 65.1 6e-10
7ylg_A A Toll-like receptor 2 62.8 6e-10
1u0n_D D Platelet glycoprotein Ib 64.7 6e-10
5uff_A A RBC36 63.5 7e-10
8c7h_E I Transforming growth factor beta activator LRRC32 66.6 7e-10
3e6j_A A Variable lymphocyte receptor diversity region 63.9 8e-10
1p8v_A A Platelet glycoprotein Ib alpha chain 64.7 9e-10
1m10_B B Glycoprotein Ib alpha 64.7 9e-10
1qyy_A A Platelet glycoprotein Ib alpha chain 64.7 9e-10
1qyy_B G Platelet glycoprotein Ib alpha chain 64.7 9e-10
1p9a_A G Platelet glycoprotein Ib alpha chain precursor 64.7 9e-10
6xfq_A G Platelet glycoprotein Ib alpha chain 64.7 9e-10
5ufd_B B RBC36 63.5 9e-10
1sq0_B B Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalp... 64.7 9e-10
5ufd_A A RBC36 63.5 1e-09
1m0z_B B Glycoprotein Ib alpha 64.3 1e-09
1ook_D G Platelet glycoprotein Ib alpha chain precursor 64.7 1e-09
1gwb_A A PLATELET GLYCOPROTEIN IB ALPHA CHAIN 64.3 1e-09
4cnc_A A TROPHOBLAST GLYCOPROTEIN 64.7 1e-09
4v2d_A A FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2 64.7 1e-09
1gwb_B B PLATELET GLYCOPROTEIN IB ALPHA CHAIN 64.3 1e-09
4v2c_C C FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2 64.7 1e-09
4v2c_A A FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2 64.7 1e-09
3pmh_C G Platelet glycoprotein Ib alpha chain 64.3 1e-09
5ftt_B B LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 64.7 1e-09
5ftu_J J LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 64.7 1e-09
5ftu_F F LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 64.7 1e-09
5ftu_B B LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 64.7 1e-09
2o6r_A A Variable lymphocyte receptor B 62.0 1e-09
6s6q_B B LRR receptor-like serine/threonine-protein kinase GSO1 66.2 1e-09
6s6q_A A LRR receptor-like serine/threonine-protein kinase GSO1 66.2 1e-09
5ftt_F F LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2 64.7 1e-09
7r54_A A Toll-like receptor 8 65.9 1e-09
6f2o_A A Leucine-rich repeat and fibronectin type-III domain-cont... 64.7 2e-09
5xwt_B B Leucine-rich repeat and fibronectin type-III domain-cont... 64.7 2e-09
5xwt_D D Leucine-rich repeat and fibronectin type-III domain-cont... 64.7 2e-09
4k5u_D D Variable lymphocyte receptor 62.4 2e-09
4k5u_C C Variable lymphocyte receptor 62.4 2e-09
4k79_A A Variable lymphocyte receptor 62.4 2e-09
4k79_D D Variable lymphocyte receptor 62.4 2e-09
4k79_B B Variable lymphocyte receptor 62.4 2e-09
4k79_C C Variable lymphocyte receptor 62.4 2e-09
4k5u_A B Variable lymphocyte receptor 62.4 2e-09
4k5u_B A Variable lymphocyte receptor 62.4 2e-09
5xnp_B B Leucine-rich repeat and fibronectin type-III domain-cont... 64.3 2e-09
5xnp_A A Leucine-rich repeat and fibronectin type-III domain-cont... 64.3 2e-09
1m0z_A A Glycoprotein Ib alpha 63.5 2e-09
5xws_A A Leucine-rich repeat and fibronectin type-III domain-cont... 63.5 4e-09
5xnq_A A Leucine-rich repeat and fibronectin type-III domain-cont... 63.2 5e-09
4xgo_A A Anopheles Plasmodium-responsive Leucine-rich repeat prot... 62.8 5e-09
7ylf_A A Toll-like receptor 15 60.1 6e-09
4cnm_A A TROPHOBLAST GLYCOPROTEIN 62.0 6e-09
3v44_A A Toll-like receptor 5b and variable lymphocyte receptor B... 62.8 7e-09
2j67_A A TOLL LIKE RECEPTOR 10 59.7 9e-09
3g3a_A A Variable lymphocyte receptor VLRB.2D 59.3 1e-08
3g3a_C C Variable lymphocyte receptor VLRB.2D 59.3 1e-08
3g3a_E E Variable lymphocyte receptor VLRB.2D 59.3 1e-08
1o77_C C TOLL-LIKE RECEPTOR 2 58.2 1e-08
3g39_A A Variable lymphocyte receptor VLRB.2D 58.9 1e-08
1o77_E E TOLL-LIKE RECEPTOR 2 58.2 1e-08
3o6n_A A APL1 62.0 1e-08
7r54_B B Toll-like receptor 8 62.8 1e-08
1o77_B B TOLL-LIKE RECEPTOR 2 58.2 1e-08
3g3b_E E variable lymphocyte receptor VLRB.2D 58.5 2e-08
5wk4_B A Variable lymphocyte receptor 39 58.9 2e-08
5wk4_F F Variable lymphocyte receptor 39 58.9 2e-08
5wk4_E E Variable lymphocyte receptor 39 58.9 2e-08
5wk4_D C Variable lymphocyte receptor 39 58.9 2e-08
5wk4_C B Variable lymphocyte receptor 39 58.9 2e-08
5wk4_A D Variable lymphocyte receptor 39 58.9 2e-08
3g3a_G G Variable lymphocyte receptor VLRB.2D 58.2 3e-08
3g3b_A A variable lymphocyte receptor VLRB.2D 57.8 3e-08
3g3b_C C variable lymphocyte receptor VLRB.2D 57.8 3e-08
6ejx_A D Platelet glycoprotein Ib alpha chain 59.7 3e-08
6ejx_B A Platelet glycoprotein Ib alpha chain 59.7 3e-08
1o77_D D TOLL-LIKE RECEPTOR 2 57.0 3e-08
1o77_A A TOLL-LIKE RECEPTOR 2 57.0 3e-08
7la7_A A variable lymphocyte receptor O6 57.8 4e-08
3rg1_C I CD180 molecule 60.8 4e-08
4xgo_B B Anopheles Plasmodium-responsive Leucine-rich repeat prot... 59.7 5e-08
6wml_C C Toll-like receptor 8 60.8 5e-08
6wml_D D Toll-like receptor 8 60.8 6e-08
8h24_A A Leucine-rich alpha-2-glycoprotein 59.3 6e-08
4z5w_A A Phytosulfokine receptor 1 60.1 8e-08
4z61_B B Phytosulfokine receptor 1 60.1 8e-08
4z61_A A Phytosulfokine receptor 1 60.1 8e-08
3oja_B B Anopheles Plasmodium-responsive Leucine-rich repeat prot... 60.1 8e-08
6bxc_D C Variable Lymphocyte Receptor 9 (VLR9) 56.6 9e-08
4z5w_B B Phytosulfokine receptor 1 60.1 9e-08
6bxe_B B Variable lymphocyte receptor diversity region 56.6 1e-07
6bxc_C D Variable Lymphocyte Receptor 9 (VLR9) 56.6 1e-07
4z62_A A Phytosulfokine receptor 1 59.7 1e-07
6bxe_A A Variable lymphocyte receptor diversity region 56.2 1e-07
4rcw_B B SLIT and NTRK-like protein 1 57.4 1e-07
4rcw_A A SLIT and NTRK-like protein 1 57.4 1e-07
5d3i_A A Toll-like receptor 2 59.3 1e-07
8hpw_B B Leucine-rich glioma-inactivated protein 1 56.6 1e-07
8hpx_B B Leucine-rich glioma-inactivated protein 1 56.6 1e-07
8hpx_A A Leucine-rich glioma-inactivated protein 1 56.6 1e-07
8hpw_C C Leucine-rich glioma-inactivated protein 1 56.6 1e-07
8hpw_A A Leucine-rich glioma-inactivated protein 1 56.6 1e-07
5xjx_D D Protein TOO MANY MOUTHS 58.9 1e-07
5xjx_G J Protein TOO MANY MOUTHS 58.9 1e-07
5xjx_F H Protein TOO MANY MOUTHS 58.9 1e-07
5xjx_E L Protein TOO MANY MOUTHS 58.9 1e-07
5xjx_C F Protein TOO MANY MOUTHS 58.9 1e-07
5xjx_A C Protein TOO MANY MOUTHS 58.9 1e-07
5xkj_D D Protein TOO MANY MOUTHS 58.5 2e-07
5xkj_A C Protein TOO MANY MOUTHS 58.5 2e-07
5y30_A A Leucine-rich glioma-inactivated protein 1 56.6 2e-07
6ka7_B B repebody 57.4 2e-07
1fyw_A A TOLL-LIKE RECEPTOR 2 55.8 2e-07
7la8_B B O6 variable lymphocyte receptor 55.5 2e-07
7la8_A A O6 variable lymphocyte receptor 55.5 2e-07
8tzf_A A Leucine-rich repeat serine/threonine-protein kinase 2 59.3 2e-07
7li3_A A Leucine-rich repeat serine/threonine-protein kinase 2 58.9 2e-07
8u8a_A B Leucine-rich repeat serine/threonine-protein kinase 2 58.9 3e-07
8u8a_B C Leucine-rich repeat serine/threonine-protein kinase 2 58.9 3e-07
8u7l_B A Leucine-rich repeat serine/threonine-protein kinase 2 58.9 3e-07
8u7l_A B Leucine-rich repeat serine/threonine-protein kinase 2 58.9 3e-07
8tzh_B A Leucine-rich repeat serine/threonine-protein kinase 2 58.9 3e-07
8u8b_B B Leucine-rich repeat serine/threonine-protein kinase 2 58.9 3e-07
8u8b_A A Leucine-rich repeat serine/threonine-protein kinase 2 58.9 3e-07
7li4_A A Leucine-rich repeat serine/threonine-protein kinase 2 58.9 3e-07
7lht_B B Leucine-rich repeat serine/threonine-protein kinase 2 58.9 3e-07
7lht_A A Leucine-rich repeat serine/threonine-protein kinase 2 58.9 3e-07
4p8s_A A Reticulon-4 receptor-like 2 57.0 3e-07
7lhw_A A Leucine-rich repeat serine/threonine-protein kinase 2 58.9 3e-07
8fo9_F F Leucine-rich repeat serine/threonine-protein kinase 2 58.5 3e-07
8fo8_D E Leucine-rich repeat serine/threonine-protein kinase 2 58.5 3e-07
8fo8_C C Leucine-rich repeat serine/threonine-protein kinase 2 58.5 3e-07
5cmp_C C Leucine-rich repeat transmembrane protein FLRT3 57.0 3e-07
7drb_B C Membrane-localized LRR receptor-like protein 58.2 3e-07
7drb_D D Membrane-localized LRR receptor-like protein 58.2 3e-07
1fyx_A A TOLL-LIKE RECEPTOR 2 54.7 3e-07
7drc_B C Membrane-localized LRR receptor-like protein 58.2 3e-07
8hq2_B D Leucine-rich glioma-inactivated protein 1 57.8 3e-07
8hq2_D E Leucine-rich glioma-inactivated protein 1 57.8 3e-07
8fo9_E E Leucine-rich repeat serine/threonine-protein kinase 2 58.5 3e-07
8fo2_B E Leucine-rich repeat serine/threonine-protein kinase 2 58.5 3e-07
6jbu_B B Leucine-rich repeat transmembrane protein FLRT3 57.0 4e-07
8y6b_B D Leucine-rich glioma-inactivated protein 1 57.8 4e-07
8y6b_F E Leucine-rich glioma-inactivated protein 1 57.8 4e-07
8y6b_E F Leucine-rich glioma-inactivated protein 1 57.8 4e-07
8hq1_E E Leucine-rich glioma-inactivated protein 1 57.8 4e-07
8hpy_D E Leucine-rich glioma-inactivated protein 1 57.8 4e-07
8hq1_F F Leucine-rich glioma-inactivated protein 1 57.8 4e-07
8hq1_D D Leucine-rich glioma-inactivated protein 1 57.8 4e-07
8hpy_B D Leucine-rich glioma-inactivated protein 1 57.8 4e-07
5cmn_D D Leucine-rich repeat transmembrane protein FLRT3 57.0 4e-07
5cmn_C C Leucine-rich repeat transmembrane protein FLRT3 57.0 4e-07
5cmn_B B Leucine-rich repeat transmembrane protein FLRT3 57.0 4e-07
5cmn_A A Leucine-rich repeat transmembrane protein FLRT3 57.0 4e-07
5y31_D D Leucine-rich glioma-inactivated protein 1 57.8 4e-07
5y31_B B Leucine-rich glioma-inactivated protein 1 57.8 4e-07
5mx0_A A Fibromodulin 57.0 4e-07
5cmp_B B Leucine-rich repeat transmembrane protein FLRT3 57.0 4e-07
7w3x_A C Membrane-localized LRR receptor-like protein 58.2 4e-07
4p91_A A Reticulon-4 receptor-like 2 56.6 4e-07
7yo4_B B Leucine-rich repeat-containing protein 26 56.6 4e-07
7yo4_F F Leucine-rich repeat-containing protein 26 56.6 4e-07
7yo4_H H Leucine-rich repeat-containing protein 26 56.6 4e-07
7yo4_D D Leucine-rich repeat-containing protein 26 56.6 4e-07
5cmp_A A Leucine-rich repeat transmembrane protein FLRT3 56.6 4e-07
2ft3_D D Biglycan 56.6 4e-07
7ynz_B B Leucine-rich repeat-containing protein 26 56.6 4e-07
7yo0_B B Leucine-rich repeat-containing protein 26 56.6 4e-07
7ynz_F F Leucine-rich repeat-containing protein 26 56.6 4e-07
7yo0_D D Leucine-rich repeat-containing protein 26 56.6 4e-07
7yo0_H H Leucine-rich repeat-containing protein 26 56.6 4e-07
7yo0_F F Leucine-rich repeat-containing protein 26 56.6 4e-07
7ynz_H H Leucine-rich repeat-containing protein 26 56.6 4e-07
7ynz_D D Leucine-rich repeat-containing protein 26 56.6 4e-07
7yo3_B B Leucine-rich repeat-containing protein 26 56.6 4e-07
5mx0_B B Fibromodulin 57.0 5e-07
2ft3_A A Biglycan 56.6 5e-07
2ft3_E E Biglycan 56.6 5e-07
2ft3_C C Biglycan 56.6 5e-07
2ft3_B B Biglycan 56.6 5e-07
7yo1_B B Leucine-rich repeat-containing protein 26 56.6 5e-07
7yo1_F F Leucine-rich repeat-containing protein 26 56.6 5e-07
7yo1_H H Leucine-rich repeat-containing protein 26 56.6 5e-07
7yo1_D D Leucine-rich repeat-containing protein 26 56.6 5e-07
2ft3_F F Biglycan 56.6 5e-07
5yq5_D D Osteomodulin 57.0 5e-07
5yq5_A A Osteomodulin 57.0 5e-07
4j0m_B B Serine/threonine-protein kinase BRI1-like 1 57.4 6e-07
4j0m_A A Serine/threonine-protein kinase BRI1-like 1 57.4 6e-07
5yq5_C C Osteomodulin 57.0 6e-07
5yq5_B B Osteomodulin 57.0 6e-07
7w3v_B C Membrane-localized LRR receptor-like protein 57.4 6e-07
5xjo_D C Protein TOO MANY MOUTHS 56.6 6e-07
5xjo_E D Protein TOO MANY MOUTHS 56.6 6e-07
5cmp_D D Leucine-rich repeat transmembrane protein FLRT3 56.2 7e-07
4rca_B B SLIT and NTRK-like protein 1 55.1 8e-07
2z82_A A Toll-like receptor 2, Variable lymphocyte receptor B 56.6 9e-07
2z81_A A Toll-like receptor 2, Variable lymphocyte receptor B 56.6 9e-07
6tl8_B B Myeloid cell surface antigen CD33,Leucine-rich repeat an... 55.5 1e-06
2v70_B B SLIT HOMOLOG 2 PROTEIN N-PRODUCT 54.3 1e-06
2v70_D D SLIT HOMOLOG 2 PROTEIN N-PRODUCT 54.3 1e-06
2v70_C C SLIT HOMOLOG 2 PROTEIN N-PRODUCT 54.3 1e-06
2v70_A A SLIT HOMOLOG 2 PROTEIN N-PRODUCT 54.3 1e-06
4v2e_A A FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 3 55.5 1e-06
4v2e_B B FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 3 55.5 1e-06
6tl8_A A Myeloid cell surface antigen CD33,Leucine-rich repeat an... 55.1 1e-06
4xsq_B B variable lymphocyte receptor-like protein Bf66946 53.5 1e-06
6tl8_C C Myeloid cell surface antigen CD33,Leucine-rich repeat an... 54.7 1e-06
4yeb_B B Fibronectin leucine rich transmembrane protein 3 55.5 1e-06
4xsq_A A variable lymphocyte receptor-like protein Bf66946 53.5 2e-06
3a7c_A A Toll-like receptor 2, Variable lymphocyte receptor B 55.1 3e-06
3a79_A A Toll-like receptor 2, Variable lymphocyte receptor B 55.1 3e-06
3a7b_A A Toll-like receptor 2, Variable lymphocyte receptor B 55.1 3e-06
2xot_B B Amphoterin-induced protein 1 54.3 3e-06
1w8a_A A SLIT PROTEIN 52.4 3e-06
4u06_A A LIC10831 53.9 4e-06
5il7_B B Rab family protein 54.3 4e-06
5il7_A A Rab family protein 54.3 4e-06
6tl8_D D Myeloid cell surface antigen CD33,Leucine-rich repeat an... 53.5 4e-06
6hlu_B B Rab family protein 54.3 6e-06
8r4c_B A Rab family protein 54.3 6e-06
8r4b_A A Rab family protein 54.3 6e-06
6m04_D D Volume-regulated anion channel subunit LRRC8D 54.3 6e-06
6m04_B B Volume-regulated anion channel subunit LRRC8D 54.3 6e-06
6m04_A A Volume-regulated anion channel subunit LRRC8D 54.3 6e-06
6m04_E E Volume-regulated anion channel subunit LRRC8D 54.3 6e-06
6m04_F F Volume-regulated anion channel subunit LRRC8D 54.3 6e-06
6m04_C C Volume-regulated anion channel subunit LRRC8D 54.3 6e-06
3twi_D D Variable lymphocyte receptor B 51.2 6e-06
8f79_C C Volume-regulated anion channel subunit LRRC8A,Soluble cy... 53.9 7e-06
8f77_A A Volume-regulated anion channel subunit LRRC8A,Soluble cy... 53.9 7e-06
8f79_A A Volume-regulated anion channel subunit LRRC8A,Soluble cy... 53.9 7e-06
8f79_E E Volume-regulated anion channel subunit LRRC8A,Soluble cy... 53.9 7e-06
5xwu_B B Leucine-rich repeat and fibronectin type III domain-cont... 53.1 7e-06
8f79_B B Volume-regulated anion channel subunit LRRC8A,Soluble cy... 53.9 7e-06
8f77_B B Volume-regulated anion channel subunit LRRC8A,Soluble cy... 53.9 7e-06
6hlu_A A Rab family protein 53.9 7e-06
7p6k_C C Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
6g9l_A A Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5y_E E Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p6k_F F Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5v_A A Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5w_E E Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
6g9o_E E Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
6g9l_E E Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p6k_E E Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5w_D D Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
6g9l_D D Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p6k_D D Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p6k_B B Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p6k_A A Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p60_D D Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p60_C C Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p60_B B Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5y_D D Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5y_C C Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p60_A A Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5y_F F Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5y_B B Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5w_C C Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5w_B B Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
6g9o_A A Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
6g9l_F F Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5y_A A Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5v_C C Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5w_A A Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5v_E E Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
6g9o_B B Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
6g9o_C C Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
6g9o_F F Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
6g9o_D D Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
6g9l_C C Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
6g9l_B B Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p60_E E Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p60_F F Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
7p5w_F F Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
5xwu_D D Leucine-rich repeat and fibronectin type III domain-cont... 53.1 7e-06
8b42_D D Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
8b42_C C Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
8b41_C C Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
8b41_A A Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
8b42_A A Volume-regulated anion channel subunit LRRC8A 53.9 7e-06
8ds3_C C Volume-regulated anion channel subunit LRRC8A,Soluble cy... 53.9 7e-06
8ds3_A A Volume-regulated anion channel subunit LRRC8A,Soluble cy... 53.9 7e-06
8ds3_E E Volume-regulated anion channel subunit LRRC8A,Soluble cy... 53.9 7e-06
8ds3_B B Volume-regulated anion channel subunit LRRC8A,Soluble cy... 53.9 7e-06
8dre_A A Volume-regulated anion channel subunit LRRC8A,Soluble cy... 53.9 7e-06
8b42_B B Volume-regulated anion channel subunit LRRC8A 53.9 8e-06
8dre_B B Volume-regulated anion channel subunit LRRC8A,Soluble cy... 53.9 8e-06
7p5v_B B Volume-regulated anion channel subunit LRRC8A 53.5 9e-06
7p5v_F F Volume-regulated anion channel subunit LRRC8A 53.5 9e-06
7p5v_D D Volume-regulated anion channel subunit LRRC8A 53.5 9e-06
8b41_B B Volume-regulated anion channel subunit LRRC8A 53.5 9e-06
8b41_D D Volume-regulated anion channel subunit LRRC8A 53.5 9e-06
3twi_E E Variable lymphocyte receptor B 50.4 1e-05
7d2t_C C Ras suppressor protein 1 51.2 2e-05
7d2u_A A Ras suppressor protein 1 51.2 2e-05
7d2t_A A Ras suppressor protein 1 51.2 2e-05
4q3i_B B OsSERK2 D128N 50.8 2e-05
7lt9_A A Ras suppressor protein 1 51.2 2e-05
7xzh_A A Volume-regulated anion channel subunit LRRC8A 52.4 2e-05
2xot_A A Amphoterin-induced protein 1 51.6 2e-05
5zsu_F F Volume-regulated anion channel subunit LRRC8A 52.4 2e-05
5zsu_D D Volume-regulated anion channel subunit LRRC8A 52.4 2e-05
5zsu_B B Volume-regulated anion channel subunit LRRC8A 52.4 2e-05
7lt8_A A Ras suppressor protein 1 51.2 2e-05
5zsu_C C Volume-regulated anion channel subunit LRRC8A 52.4 2e-05
5zsu_A A Volume-regulated anion channel subunit LRRC8A 52.4 2e-05
5zsu_E E Volume-regulated anion channel subunit LRRC8A 52.4 2e-05
7xzh_C C Volume-regulated anion channel subunit LRRC8A 52.4 2e-05
7xzh_F F Volume-regulated anion channel subunit LRRC8A 52.4 2e-05
7xzh_E E Volume-regulated anion channel subunit LRRC8A 52.4 2e-05
7xzh_D D Volume-regulated anion channel subunit LRRC8A 52.4 2e-05
7xzh_B B Volume-regulated anion channel subunit LRRC8A 52.4 2e-05
4q3i_A A OsSERK2 D128N 50.4 2e-05
6djb_A A Volume-regulated anion channel subunit LRRC8A 52.0 2e-05
6djb_E C Volume-regulated anion channel subunit LRRC8A 52.0 2e-05
6djb_C E Volume-regulated anion channel subunit LRRC8A 52.0 2e-05
6djb_F D Volume-regulated anion channel subunit LRRC8A 52.0 3e-05
6djb_D F Volume-regulated anion channel subunit LRRC8A 52.0 3e-05
6djb_B B Volume-regulated anion channel subunit LRRC8A 52.0 3e-05
4mn8_A A LRR receptor-like serine/threonine-protein kinase FLS2 51.6 4e-05
8b40_E E Volume-regulated anion channel subunit LRRC8C 51.6 4e-05
8b40_A A Volume-regulated anion channel subunit LRRC8C 51.6 4e-05
8b40_G G Volume-regulated anion channel subunit LRRC8C 51.6 4e-05
8b40_D D Volume-regulated anion channel subunit LRRC8C 51.6 4e-05
8b40_B B Volume-regulated anion channel subunit LRRC8C 51.6 4e-05
8b40_F F Volume-regulated anion channel subunit LRRC8C 51.6 4e-05
8b40_C C Volume-regulated anion channel subunit LRRC8C 51.6 4e-05
8b42_E E Volume-regulated anion channel subunit LRRC8C 51.6 4e-05
5gqr_A B Leucine-rich repeat receptor-like protein kinase TDR 51.2 4e-05
5gr9_A B Leucine-rich repeat receptor-like protein kinase TDR 51.2 4e-05
2omu_A A Internalin-A 50.8 5e-05
2omv_A A Internalin-A 50.8 5e-05
2omw_A A Internalin-A 50.8 5e-05
7d2s_A A Ras suppressor protein 1 49.3 5e-05
2omx_A A Internalin-A 50.8 5e-05
4mna_A A LRR receptor-like serine/threonine-protein kinase FLS2 51.2 5e-05
6fnw_A A Volume-regulated anion channel subunit LRRC8A 50.4 6e-05
4y61_B B SLIT and NTRK-like protein 2 49.7 6e-05
4q3g_B B OsSERK2 49.3 7e-05
7y1r_C E Transforming growth factor beta activator LRRC33 50.4 7e-05
8f75_B B Volume-regulated anion channel subunit LRRC8A 50.8 7e-05
8f75_A A Volume-regulated anion channel subunit LRRC8A 50.8 7e-05
8f7e_A B Volume-regulated anion channel subunit LRRC8A,Soluble cy... 50.8 8e-05
8f7j_A E Volume-regulated anion channel subunit LRRC8A,Soluble cy... 50.8 8e-05
8f7e_B C Volume-regulated anion channel subunit LRRC8A,Soluble cy... 50.8 8e-05
8dra_A A Volume-regulated anion channel subunit LRRC8A,Soluble cy... 50.8 8e-05
8f7d_A A Volume-regulated anion channel subunit LRRC8A,Soluble cy... 50.8 8e-05
8dro_A B Volume-regulated anion channel subunit LRRC8A,Soluble cy... 50.8 8e-05
8drn_A A Volume-regulated anion channel subunit LRRC8A,Soluble cy... 50.8 8e-05
8dro_B C Volume-regulated anion channel subunit LRRC8A,Soluble cy... 50.8 8e-05
8drq_A E Volume-regulated anion channel subunit LRRC8A,Soluble cy... 50.8 8e-05
8dra_B B Volume-regulated anion channel subunit LRRC8A,Soluble cy... 50.8 8e-05
4q3g_A A OsSERK2 48.9 8e-05
2omt_A A Internalin-A 50.1 8e-05
2omy_A A Internalin-A 50.1 9e-05
2omz_A A Internalin-A 50.1 9e-05
5gij_A B Leucine-rich repeat receptor-like protein kinase TDR 50.1 9e-05
5jfk_A A Leucine-rich repeat receptor-like protein kinase TDR 50.1 9e-05
5jfi_C B Leucine-rich repeat receptor-like protein kinase TDR 50.1 9e-05
5jfi_A A Leucine-rich repeat receptor-like protein kinase TDR 50.1 9e-05
5jfk_B B Leucine-rich repeat receptor-like protein kinase TDR 50.1 9e-05
2wfh_B B SLIT HOMOLOG 2 PROTEIN C-PRODUCT 48.1 1e-04
2wfh_A A SLIT HOMOLOG 2 PROTEIN C-PRODUCT 48.1 1e-04
8ds3_F F Volume-regulated anion channel subunit LRRC8C 50.1 1e-04
8f77_F F Volume-regulated anion channel subunit LRRC8C 50.1 1e-04
8f79_F F Volume-regulated anion channel subunit LRRC8C 50.1 1e-04
8dre_F F Volume-regulated anion channel subunit LRRC8C 50.1 1e-04
3jb9_HA j U2 small nuclear ribonucleoprotein A' 48.5 1e-04
1o6v_A A INTERNALIN A 49.3 2e-04
8h64_G G Internalin A 49.3 2e-04
8h64_C C Internalin A 49.3 2e-04
1o6s_A A INTERNALIN A 49.3 2e-04
1o6v_B B INTERNALIN A 49.3 2e-04
8h62_A A Internalin A 48.9 2e-04
8h63_A A Internalin A 48.9 2e-04
1o6t_A A INTERNALIN A 48.9 2e-04
8ben_A A Volume-regulated anion channel subunit LRRC8C 48.9 2e-04
4hq1_A A Probable receptor protein kinase TMK1 48.9 2e-04
8ben_B B Volume-regulated anion channel subunit LRRC8C 48.9 2e-04
8h64_A A Internalin A 48.9 2e-04
8h64_E E Internalin A 48.9 2e-04
2r9u_A A Variable lymphocyte receptor 46.6 2e-04
2r9u_B B Variable lymphocyte receptor 46.6 2e-04
2r9u_D D Variable lymphocyte receptor 46.6 2e-04
2r9u_C C Variable lymphocyte receptor 46.6 2e-04
7odk_B BBB Receptor-like protein kinase HSL1 48.5 3e-04
4r58_D D Leucine Rich Repeat protein 46.6 4e-04
4r58_B B Leucine Rich Repeat protein 46.6 4e-04
4r58_A A Leucine Rich Repeat protein 46.6 4e-04
4r58_C C Leucine Rich Repeat protein 46.6 4e-04
3a79_B B Toll-like receptor 6, Variable lymphocyte receptor B 48.1 4e-04
7ogo_D DDD Receptor-like protein kinase HSL1 48.1 4e-04
7ogu_J JJJ Receptor-like protein kinase HSL1 48.1 4e-04
7ogq_A AAA Receptor-like protein kinase HSL1 48.1 4e-04
7odv_D DDD Receptor-like protein kinase HSL1 48.1 4e-04
7n6g_ZF 6E FAP246 48.1 4e-04
7n6g_AG 6F FAP246 48.1 4e-04
7ogo_A AAA Receptor-like protein kinase HSL1 48.1 4e-04
7ogz_D DDD Receptor-like protein kinase HSL1 47.8 5e-04
7ogu_D DDD Receptor-like protein kinase HSL1 47.8 5e-04
7ogu_G GGG Receptor-like protein kinase HSL1 47.8 5e-04
7ogu_A AAA Receptor-like protein kinase HSL1 47.8 5e-04
7odv_A AAA Receptor-like protein kinase HSL1 47.8 5e-04
7odk_A AAA Receptor-like protein kinase HSL1 47.8 5e-04
7ogz_A AAA Receptor-like protein kinase HSL1 47.8 6e-04
2z80_B B Toll-like receptor 2, Variable lymphocyte receptor B 47.0 6e-04
8ben_C C Volume-regulated anion channel subunit LRRC8C 47.4 6e-04
2z80_A A Toll-like receptor 2, Variable lymphocyte receptor B 47.0 6e-04
7tvf_E A Leucine-rich repeat protein SHOC-2 47.4 7e-04
7sqc_KM X3 FAP246 47.8 7e-04
7sqc_JM X2 FAP246 47.8 7e-04
7sqc_IM X1 FAP246 47.8 7e-04
7sqc_HM X0 FAP246 47.8 7e-04
8drn_B F Volume-regulated anion channel subunit LRRC8C 47.4 7e-04
8f7d_B F Volume-regulated anion channel subunit LRRC8C 47.4 7e-04
8dra_C F Volume-regulated anion channel subunit LRRC8C 47.4 7e-04
8f75_C F Volume-regulated anion channel subunit LRRC8C 47.4 7e-04
7txh_E E Leucine-rich repeat protein SHOC-2 47.4 7e-04
8glv_AR Eb Flagellar associated protein 47.8 7e-04
7sd0_A A Leucine-rich repeat protein SHOC-2 47.4 7e-04
7txh_B B Leucine-rich repeat protein SHOC-2 47.0 7e-04
7tyg_A A Leucine-rich repeat protein SHOC-2 47.0 7e-04
7tyg_B B Leucine-rich repeat protein SHOC-2 47.0 8e-04
7t7a_B B Leucine-rich repeat protein SHOC-2 47.0 8e-04
7t7a_A A Leucine-rich repeat protein SHOC-2 47.0 8e-04
7sd1_B B Leucine-rich repeat protein SHOC-2 47.0 8e-04
6nih_A A Toll-like receptor 1,Variable lymphocyte receptor B 47.0 8e-04
2z7x_B B Toll-like receptor 1,Variable lymphocyte receptor B 47.0 8e-04
7sd1_C C Leucine-rich repeat protein SHOC-2 47.0 8e-04
7sd1_D D Leucine-rich repeat protein SHOC-2 47.0 8e-04
6nih_B B Toll-like receptor 1,Variable lymphocyte receptor B 47.0 8e-04
7sd1_A A Leucine-rich repeat protein SHOC-2 47.0 9e-04
7tvf_F D Leucine-rich repeat protein SHOC-2 47.0 9e-04
7upi_C C Leucine-rich repeat protein SHOC-2 47.0 0.001
7tvg_A D Leucine-rich repeat protein SHOC-2 46.6 0.001
4u09_B B LIC12759 46.2 0.001
8ben_D D Volume-regulated anion channel subunit LRRC8C 45.8 0.002
4u09_A A LIC12759 45.4 0.002
5b0n_A A E3 ubiquitin-protein ligase ipaH9.8 44.7 0.002
8i2g_E R Follicle-stimulating hormone receptor 45.8 0.002
5b0t_A A E3 ubiquitin-protein ligase ipaH9.8 44.3 0.002
6loj_A A Invasion plasmid antigen 44.3 0.002
5b0n_B B E3 ubiquitin-protein ligase ipaH9.8 44.3 0.002
6lol_A A E3 ubiquitin-protein ligase ipaH9.8 45.4 0.002
6k2d_B B E3 ubiquitin-protein ligase ipaH9.8 44.3 0.002
6zxg_JA k Leucine-rich repeat-containing protein 47 45.1 0.003
6zxe_JA k Leucine-rich repeat-containing protein 47 45.1 0.003
6zxd_KA k Leucine-rich repeat-containing protein 47 45.1 0.003
6zxf_KA k Leucine-rich repeat-containing protein 47 45.1 0.003
4ay9_H Y FOLLICLE-STIMULATING HORMONE RECEPTOR 44.7 0.004
4ay9_I Z FOLLICLE-STIMULATING HORMONE RECEPTOR 44.7 0.004
4ay9_G X FOLLICLE-STIMULATING HORMONE RECEPTOR 44.7 0.004
6obn_C C Protein phosphatase 1 regulatory subunit 7 43.9 0.005
8b5r_I S Protein phosphatase 1 regulatory subunit 7 43.9 0.005
8u5g_B B Protein phosphatase 1 regulatory subunit 7 43.9 0.006
6obn_D D Protein phosphatase 1 regulatory subunit 7 43.9 0.006
6obp_B C Protein phosphatase 1 regulatory subunit 7 43.5 0.006
6hkw_A A Protein phosphatase 1 regulatory subunit 7 43.9 0.006
6hkw_E E Protein phosphatase 1 regulatory subunit 7 43.9 0.006
6hkw_B B Protein phosphatase 1 regulatory subunit 7 43.9 0.006
6hkw_C C Protein phosphatase 1 regulatory subunit 7 43.9 0.006
6hkw_D D Protein phosphatase 1 regulatory subunit 7 43.9 0.006
4mqw_I Z Follicle-stimulating hormone receptor 43.9 0.007
6mky_A A Protein phosphatase 1 regulatory subunit 7 43.1 0.007
4mqw_C X Follicle-stimulating hormone receptor 43.5 0.007
6mky_B B Protein phosphatase 1 regulatory subunit 7 43.1 0.008
8i2h_A A Follicle-stimulating hormone receptor 43.9 0.008
1xwd_F F Follicle stimulating hormone receptor 42.7 0.008
4mqw_F Y Follicle-stimulating hormone receptor 43.5 0.009
1xwd_C C Follicle stimulating hormone receptor 42.4 0.011
4z64_A A Phytosulfokine receptor 1 43.1 0.015
4z63_A A Phytosulfokine receptor 1 42.7 0.016
2z7x_A A Toll-like receptor 2,Variable lymphocyte receptor B 42.0 0.027
6nig_D D Toll-like receptor 2,Variable lymphocyte receptor B 42.4 0.027
6nig_B B Toll-like receptor 2,Variable lymphocyte receptor B 42.0 0.027
6nig_C C Toll-like receptor 2,Variable lymphocyte receptor B 42.0 0.027
6nig_A A Toll-like receptor 2,Variable lymphocyte receptor B 42.0 0.027
5xjx_B K LRR receptor-like serine/threonine-protein kinase ERL1 42.0 0.029
5xjx_J I LRR receptor-like serine/threonine-protein kinase ERL1 42.0 0.029
5xjx_L E LRR receptor-like serine/threonine-protein kinase ERL1 42.0 0.029
5xjx_K B LRR receptor-like serine/threonine-protein kinase ERL1 42.0 0.029
5xjx_I A LRR receptor-like serine/threonine-protein kinase ERL1 42.0 0.029
5xjx_H G LRR receptor-like serine/threonine-protein kinase ERL1 42.0 0.029
5y9w_A B Pollen receptor-like kinase 6 41.2 0.031
5yah_A B Pollen receptor-like kinase 6 40.8 0.035
5y9w_C A Pollen receptor-like kinase 6 40.8 0.040
7fch_A A Interleukin-18 receptor accessory protein 39.7 0.045
7fch_B B Interleukin-18 receptor accessory protein 39.7 0.045
7fch_D D Interleukin-18 receptor accessory protein 39.7 0.045
7fch_C C Interleukin-18 receptor accessory protein 39.7 0.045
5xkj_E B LRR receptor-like serine/threonine-protein kinase ERL1 40.8 0.061
5xkj_C A LRR receptor-like serine/threonine-protein kinase ERL1 40.8 0.061
5xjo_F B LRR receptor-like serine/threonine-protein kinase ERL1 40.8 0.067
5xjo_A A LRR receptor-like serine/threonine-protein kinase ERL1 40.8 0.067
4puf_A A E3 ubiquitin-protein ligase SlrP 40.8 0.069
4puf_B B E3 ubiquitin-protein ligase SlrP 40.8 0.069
8fac_A A Leucine-rich repeat serine/threonine-protein kinase 1 40.4 0.11
5hz0_A B Probable LRR receptor-like serine/threonine-protein kina... 39.7 0.15
5hz1_A B Probable LRR receptor-like serine/threonine-protein kina... 39.7 0.16
5hz3_A B Probable LRR receptor-like serine/threonine-protein kina... 39.7 0.16
5hyx_A B Probable LRR receptor-like serine/threonine-protein kina... 39.7 0.18
7ax1_A A CCR4-NOT transcription complex subunit 6 39.7 0.18
7brc_A A Receptor-like kinase TMK3 39.3 0.18
5xkn_C B LRR receptor-like serine/threonine-protein kinase ERL2 39.3 0.19
5xkn_B A LRR receptor-like serine/threonine-protein kinase ERL2 39.3 0.19
8esf_B B Nischarin 38.9 0.23
3cvr_A A Invasion plasmid antigen 39.3 0.23
8e06_A A Leucine-rich repeat serine/threonine-protein kinase 1 39.3 0.23
8e05_A A Leucine-rich repeat serine/threonine-protein kinase 1 39.3 0.23
8e05_B B Leucine-rich repeat serine/threonine-protein kinase 1 39.3 0.23
8esf_A A Nischarin 38.5 0.33
6w78_A A Antifreeze polypeptide 38.1 0.35
5hl3_A A Lmo2470 protein 38.1 0.38
5gr8_B D Leucine-rich repeat receptor-like protein kinase PEPR1 38.5 0.39
5gr8_A A Leucine-rich repeat receptor-like protein kinase PEPR1 38.5 0.39
4pbw_C C NT-3 growth factor receptor 37.0 0.83
4pbw_B A NT-3 growth factor receptor 37.0 0.86
4pbv_A A NT-3 growth factor receptor 36.6 0.87
4pbv_B B NT-3 growth factor receptor 36.6 0.87
4pbw_A B NT-3 growth factor receptor 36.6 0.87
6tme_B B Pollen-specific leucine-rich repeat extensin-like protein 1 36.6 1.0
6tme_A A Pollen-specific leucine-rich repeat extensin-like protein 1 36.6 1.1
6qwn_E C Pollen-specific leucine-rich repeat extensin-like protein 1 36.6 1.1
4tzh_B B LIC12234 35.8 1.2
4fmz_B B Internalin 36.6 1.2
6qwn_G D Pollen-specific leucine-rich repeat extensin-like protein 1 36.6 1.2
6qwn_C B Pollen-specific leucine-rich repeat extensin-like protein 1 36.6 1.2
6qwn_A A Pollen-specific leucine-rich repeat extensin-like protein 1 36.6 1.3
4tzh_A A LIC12234 35.4 1.4
8e04_A A Leucine-rich repeat serine/threonine-protein kinase 1 36.6 1.6
4fmz_A A Internalin 36.2 1.6
7utz_D R Thyrotropin receptor 36.2 1.8
1g9u_A A OUTER PROTEIN YOPM 35.8 2.0
1jl5_A A outer protein YopM 35.8 2.0
3twi_F F Variable lymphocyte receptor B 35.0 2.1
6qwn_I E Pollen-specific leucine-rich repeat extensin-like protein 1 35.8 2.1
3bz5_A A Internalin-J 35.4 2.8
4u08_B B LIC11098 35.4 2.9
4u08_A A LIC11098 35.4 2.9
4ow2_D D Yop effector YopM 35.4 3.4
4ow2_A A Yop effector YopM 35.4 3.4
4ow2_C C Yop effector YopM 35.4 3.4
4ow2_B B Yop effector YopM 35.4 3.4
3rgx_A A Protein BRASSINOSTEROID INSENSITIVE 1 35.0 4.2
4eo7_A A Myeloid differentiation primary response protein MyD88 33.5 4.9
7l6w_A A Myeloid differentiation primary response protein MyD88 33.1 5.7
4lsx_A A Protein BRASSINOSTEROID INSENSITIVE 1 34.7 5.7
4lsx_B B Protein BRASSINOSTEROID INSENSITIVE 1 34.7 5.7
6g2i_D F Acetyl-CoA carboxylase 1 34.7 5.9
6g2i_F A Acetyl-CoA carboxylase 1 34.7 5.9
6g2i_E B Acetyl-CoA carboxylase 1 34.7 5.9
6g2i_A D Acetyl-CoA carboxylase 1 34.7 5.9
6g2i_C C Acetyl-CoA carboxylase 1 34.7 5.9
6g2i_B E Acetyl-CoA carboxylase 1 34.7 5.9
4lsa_A A Protein BRASSINOSTEROID INSENSITIVE 1 34.7 5.9
6g2i_J R Acetyl-CoA carboxylase 1 34.7 6.3
6g2i_I J Acetyl-CoA carboxylase 1 34.7 6.3
6g2h_A D Acetyl-CoA carboxylase 1 34.7 6.3
6g2h_B E Acetyl-CoA carboxylase 1 34.7 6.3
3riz_A A Protein BRASSINOSTEROID INSENSITIVE 1 34.7 6.4
4m7e_A A Protein BRASSINOSTEROID INSENSITIVE 1 34.7 6.5
4m7e_B B Protein BRASSINOSTEROID INSENSITIVE 1 34.7 6.5
6g2d_C D Acetyl-CoA carboxylase 1 34.7 6.6
6g2d_B C Acetyl-CoA carboxylase 1 34.7 6.6
3rj0_A A Protein BRASSINOSTEROID INSENSITIVE 1 34.7 6.6
7beq_A A Myeloid differentiation primary response protein MyD88 33.1 6.7
7ber_A A Myeloid differentiation primary response protein MyD88 33.1 6.7
6fif_A A Protein BRASSINOSTEROID INSENSITIVE 1 34.7 6.7
2z5v_A A Myeloid differentiation primary response protein MyD88 33.1 6.8
3rgz_A A Protein BRASSINOSTEROID INSENSITIVE 1 34.3 6.8
4eco_A A Uncharacterized protein 34.3 7.0
2js7_A A Myeloid differentiation primary response protein MyD88 33.1 7.2
4eco_B B Uncharacterized protein 34.3 7.4
6g2d_A B Acetyl-CoA carboxylase 1 34.3 7.8
6g2h_E B Acetyl-CoA carboxylase 1 34.3 7.9
6g2h_F A Acetyl-CoA carboxylase 1 34.3 7.9
6g2d_D F Acetyl-CoA carboxylase 1 34.3 9.2
1xeu_A A internalin C 33.5 9.7
4xa9_M G Gala protein type 1, 3 or 4 33.5 9.9
>7c76_A A Toll-like receptor 3
Length=904
Score = 1384 bits (3582), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 691/697 (99%), Positives = 691/697 (99%), Gaps = 0/697 (0%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK
Sbjct 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
Query 90 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL
Sbjct 90 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
Query 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI
Sbjct 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
Query 210 KEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFL 269
KEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFL
Sbjct 210 KEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFL 269
Query 270 GLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
GLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL
Sbjct 270 GLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
Query 330 KRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
KRSFTKQ LPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS
Sbjct 330 KRSFTKQXXXXXXLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
Query 390 FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTG 449
FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTG
Sbjct 390 FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTG 449
Query 450 QEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLT 509
QEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLT
Sbjct 450 QEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLT 509
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL
Sbjct 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV
Sbjct 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR
Sbjct 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
Query 690 LFDTSSCKDSAPFELFFMINTSILLIFIFIVLLIHFE 726
LFDTSSCKDSAPFELFFMINTSILLIFIFIVLLIHFE
Sbjct 690 LFDTSSCKDSAPFELFFMINTSILLIFIFIVLLIHFE 726
>2a0z_A A Toll-like receptor 3
Length=705
Score = 1347 bits (3486), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 671/671 (100%), Positives = 671/671 (100%), Gaps = 0/671 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN
Sbjct 5 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 64
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK
Sbjct 65 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 124
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS
Sbjct 125 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 184
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN
Sbjct 185 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 244
Query 266 TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVR 325
TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVR
Sbjct 245 TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVR 304
Query 326 YLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
YLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS
Sbjct 305 YLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 364
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ
Sbjct 365 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 424
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL
Sbjct 425 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 484
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH
Sbjct 485 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 544
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV
Sbjct 545 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 604
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG
Sbjct 605 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 664
Query 686 FPVRLFDTSSC 696
FPVRLFDTSSC
Sbjct 665 FPVRLFDTSSC 675
>7wv3_A A Toll-like receptor 3
Length=890
Score = 1339 bits (3465), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 668/668 (100%), Positives = 668/668 (100%), Gaps = 0/668 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 665
Query 689 RLFDTSSC 696
RLFDTSSC
Sbjct 666 RLFDTSSC 673
>3ulv_A A Toll-like receptor 3
Length=694
Score = 1339 bits (3465), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 668/668 (100%), Positives = 668/668 (100%), Gaps = 0/668 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 13 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 72
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 73 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 132
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 133 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 192
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 193 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 252
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 253 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 312
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 313 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 372
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 373 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 432
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 433 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 492
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 493 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 552
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 553 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 612
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV
Sbjct 613 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 672
Query 689 RLFDTSSC 696
RLFDTSSC
Sbjct 673 RLFDTSSC 680
>7wv3_B B Toll-like receptor 3
Length=890
Score = 1339 bits (3465), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 668/668 (100%), Positives = 668/668 (100%), Gaps = 0/668 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 665
Query 689 RLFDTSSC 696
RLFDTSSC
Sbjct 666 RLFDTSSC 673
>7wv3_C C Toll-like receptor 3
Length=890
Score = 1339 bits (3465), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 668/668 (100%), Positives = 668/668 (100%), Gaps = 0/668 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 665
Query 689 RLFDTSSC 696
RLFDTSSC
Sbjct 666 RLFDTSSC 673
>7wv3_D D Toll-like receptor 3
Length=890
Score = 1339 bits (3465), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 668/668 (100%), Positives = 668/668 (100%), Gaps = 0/668 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 665
Query 689 RLFDTSSC 696
RLFDTSSC
Sbjct 666 RLFDTSSC 673
>5gs0_D B Toll-like receptor 3
Length=671
Score = 1328 bits (3436), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 663/663 (100%), Positives = 663/663 (100%), Gaps = 0/663 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 3 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 62
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 63 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 122
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 123 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 182
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 183 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 242
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 243 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 302
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 303 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 362
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 363 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 422
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 423 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 482
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 483 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 542
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 543 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 602
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV
Sbjct 603 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 662
Query 689 RLF 691
RLF
Sbjct 663 RLF 665
>5gs0_A A Toll-like receptor 3
Length=671
Score = 1328 bits (3436), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 663/663 (100%), Positives = 663/663 (100%), Gaps = 0/663 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 3 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 62
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 63 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 122
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 123 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 182
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 183 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 242
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 243 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 302
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 303 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 362
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 363 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 422
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 423 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 482
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 483 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 542
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 543 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 602
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV
Sbjct 603 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 662
Query 689 RLF 691
RLF
Sbjct 663 RLF 665
>3ulu_A A Toll-like receptor 3
Length=694
Score = 1320 bits (3416), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 659/659 (100%), Positives = 659/659 (100%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 13 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 72
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 73 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 132
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 133 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 192
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 193 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 252
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 253 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 312
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 313 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 372
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 373 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 432
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 433 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 492
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 493 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 552
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 553 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 612
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 613 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 671
>7wv4_C C Toll-like receptor 3
Length=689
Score = 1320 bits (3416), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 659/659 (100%), Positives = 659/659 (100%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 664
>7wvf_A A Toll-like receptor 3
Length=689
Score = 1320 bits (3416), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 659/659 (100%), Positives = 659/659 (100%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 664
>7wv4_B B Toll-like receptor 3
Length=689
Score = 1320 bits (3416), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 659/659 (100%), Positives = 659/659 (100%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 664
>7wv4_A A Toll-like receptor 3
Length=689
Score = 1320 bits (3416), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 659/659 (100%), Positives = 659/659 (100%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 664
>7wv5_A A Toll-like receptor 3
Length=689
Score = 1320 bits (3416), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 659/659 (100%), Positives = 659/659 (100%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 664
>7wvf_B B Toll-like receptor 3
Length=689
Score = 1320 bits (3416), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 659/659 (100%), Positives = 659/659 (100%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 664
>7wv4_D D Toll-like receptor 3
Length=689
Score = 1320 bits (3416), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 659/659 (100%), Positives = 659/659 (100%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 664
>7wv5_B B Toll-like receptor 3
Length=689
Score = 1320 bits (3416), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 659/659 (100%), Positives = 659/659 (100%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 664
>7wvj_B B Toll-like receptor 3
Length=689
Score = 1314 bits (3401), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 656/659 (99%), Positives = 656/659 (99%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSD TFAFCTNLTELHLMSNSIQKI NNPFV QKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDDTFAFCTNLTELHLMSNSIQKIDNNPFVDQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 664
>7wvj_A A Toll-like receptor 3
Length=689
Score = 1314 bits (3401), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 656/659 (99%), Positives = 656/659 (99%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSD TFAFCTNLTELHLMSNSIQKI NNPFV QKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDDTFAFCTNLTELHLMSNSIQKIDNNPFVDQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 664
>7wve_A A Toll-like receptor 3
Length=680
Score = 1313 bits (3399), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 656/659 (99%), Positives = 657/659 (99%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANIN ML+GLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINKKMLKGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 664
>7wve_B B Toll-like receptor 3
Length=680
Score = 1313 bits (3399), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 656/659 (99%), Positives = 657/659 (99%), Gaps = 0/659 (0%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS
Sbjct 6 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 65
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN
Sbjct 66 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 125
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ
Sbjct 126 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 185
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF
Sbjct 186 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 245
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN
Sbjct 246 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 305
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN
Sbjct 306 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 365
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT
Sbjct 366 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 425
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL
Sbjct 426 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 485
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
TILDLSNNNIANIN ML+GLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN
Sbjct 486 TILDLSNNNIANINKKMLKGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 545
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK
Sbjct 546 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 605
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP
Sbjct 606 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 664
>1ziw_A A Toll-like receptor 3
Length=680
Score = 1254 bits (3245), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 629/635 (99%), Positives = 629/635 (99%), Gaps = 0/635 (0%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK
Sbjct 4 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 63
Query 90 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL
Sbjct 64 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 123
Query 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI
Sbjct 124 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 183
Query 210 KEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFL 269
KEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFL
Sbjct 184 KEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFL 243
Query 270 GLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
GLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL
Sbjct 244 GLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 303
Query 330 KRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
KRSFTKQ LPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS
Sbjct 304 KRSFTKQXXXXXXLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 363
Query 390 FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTG 449
FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTG
Sbjct 364 FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTG 423
Query 450 QEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLT 509
QEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLT
Sbjct 424 QEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLT 483
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL
Sbjct 484 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 543
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV
Sbjct 544 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 603
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINET 664
FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINET
Sbjct 604 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINET 638
>7c77_A A Toll-like receptor 3
Length=905
Score = 1042 bits (2694), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 549/700 (78%), Positives = 613/700 (88%), Gaps = 0/700 (0%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+CTV + VADCSHLKLT +PDDLP+NITVLNLTHNQLRRLP NFTRYSQL LD GFN+
Sbjct 28 QCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNS 87
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
ISKLEPELCQ LP+LKVLNLQHNELSQ+SD+TF FCTNLTEL LMSNSI KIK+NPF Q
Sbjct 88 ISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQ 147
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
KNLI LDLSHNGLSSTKLGT VQLENLQELLL+ NKI AL+SEEL+ NSSL+KL+LSS
Sbjct 148 KNLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSS 207
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
N +KEFSPGCF IG+LF L LNN QL P LTEKLC EL+NTSI+NLSL+N+QL TS +
Sbjct 208 NPLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSES 267
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRY 326
TF GLKWTNLT LDLSYNNL+ VGN SF++LP L Y LEYNNIQ L S +GL N+RY
Sbjct 268 TFSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRY 327
Query 327 LNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
L+LKR+FTKQS+SLAS P IDDFSFQWLK LE+LNM+DN+IP KSN FTGL++LKYLSL
Sbjct 328 LSLKRAFTKQSVSLASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSL 387
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
S +FTSL+TLTNETFVSLAHSPL LNLTKN ISKI + FSWLG L +LDLGLNEI Q+
Sbjct 388 SKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQK 447
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
L+GQEWRGL NIFEIYLSYNKYLQL+ +SFALVPSLQRLMLRRVALKNVD SPSPF+PLR
Sbjct 448 LSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLR 507
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
NLTILDLSNNNIANIN+D+LEGLE LEILD QHNNLARLWK ANPGGP+ FLKGLSHLHI
Sbjct 508 NLTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWKRANPGGPVNFLKGLSHLHI 567
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
LNLESNG DEIPV VFK+LFELK I+LGLNNLN L +F++Q SL+SLNLQKNLITSVE
Sbjct 568 LNLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVE 627
Query 627 KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGF 686
K VFGP F+NL LDMRFNPFDCTCESI+WFVNWIN+THTNI ELS+HYLCNTP HY+GF
Sbjct 628 KDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGF 687
Query 687 PVRLFDTSSCKDSAPFELFFMINTSILLIFIFIVLLIHFE 726
P++LFDTSSCKDSAPFEL F+I+TS+LL+FI +VLLIH E
Sbjct 688 PLKLFDTSSCKDSAPFELLFIISTSMLLVFILVVLLIHIE 727
>7da7_B B Toll-like receptor 3
Length=684
Score = 1016 bits (2626), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 527/671 (79%), Positives = 585/671 (87%), Gaps = 0/671 (0%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+CTV + VADCSHLKLT +PDDLP+NITVLNLTHNQLRRLP NFTRYSQL LD GFN+
Sbjct 14 QCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNS 73
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
ISKLEPELCQ LP+LKVLNLQHNELSQ+SD+TF FCTNLTEL LMSNSI KIK+NPF Q
Sbjct 74 ISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQ 133
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
KNLI LDLSHNGLSSTKLGT VQLENLQELLL+ NKI AL+SEEL+ NSSL+KL+LSS
Sbjct 134 KNLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSS 193
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
N +KEFSPGCF IG+LF L LNN QL P LTEKLC EL+NTSI+NLSL+N+QL TS +
Sbjct 194 NPLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSES 253
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRY 326
TF GLKWTNLT LDLSYNNL+ VGN SF++LP L Y LEYNNIQ L S +GL N+RY
Sbjct 254 TFSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRY 313
Query 327 LNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
L+LKR+FTKQS LAS P IDDFSFQWLK LE+LNM+DN+IP KSN FTGL++LKYLSL
Sbjct 314 LSLKRAFTKQSXXLASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSL 373
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
S +FTSL+TLTNETFVSLAHSPL LNLTKN ISKI + FSWLG L +LDLGLNEI Q+
Sbjct 374 SKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQK 433
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
L+GQEWRGL NIFEIYLSYNKYLQL+ +SFALVPSLQRLMLRRVALKNVD SPSPF+PLR
Sbjct 434 LSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLR 493
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
NLTILDLSNNNIANIN+D+LEGLE LEILD QHNNLARLWK ANPGGP+ FLKGLSHLHI
Sbjct 494 NLTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWKRANPGGPVNFLKGLSHLHI 553
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
LNLESNG DEIPV VFK+LFELK I+LGLNNLN L +F++Q SL+SLNLQKNLITSVE
Sbjct 554 LNLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVE 613
Query 627 KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGF 686
K VFGP F+NL LDMRFNPFDCTCESI+WFVNWIN+THTNI ELS+HYLCNTP HY+GF
Sbjct 614 KDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGF 673
Query 687 PVRLFDTSSCK 697
P++LFDTSSCK
Sbjct 674 PLKLFDTSSCK 684
>7da7_A A Toll-like receptor 3
Length=684
Score = 1016 bits (2626), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 527/671 (79%), Positives = 585/671 (87%), Gaps = 0/671 (0%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+CTV + VADCSHLKLT +PDDLP+NITVLNLTHNQLRRLP NFTRYSQL LD GFN+
Sbjct 14 QCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNS 73
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
ISKLEPELCQ LP+LKVLNLQHNELSQ+SD+TF FCTNLTEL LMSNSI KIK+NPF Q
Sbjct 74 ISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQ 133
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
KNLI LDLSHNGLSSTKLGT VQLENLQELLL+ NKI AL+SEEL+ NSSL+KL+LSS
Sbjct 134 KNLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSS 193
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
N +KEFSPGCF IG+LF L LNN QL P LTEKLC EL+NTSI+NLSL+N+QL TS +
Sbjct 194 NPLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSES 253
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRY 326
TF GLKWTNLT LDLSYNNL+ VGN SF++LP L Y LEYNNIQ L S +GL N+RY
Sbjct 254 TFSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRY 313
Query 327 LNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
L+LKR+FTKQS LAS P IDDFSFQWLK LE+LNM+DN+IP KSN FTGL++LKYLSL
Sbjct 314 LSLKRAFTKQSXXLASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSL 373
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
S +FTSL+TLTNETFVSLAHSPL LNLTKN ISKI + FSWLG L +LDLGLNEI Q+
Sbjct 374 SKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQK 433
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
L+GQEWRGL NIFEIYLSYNKYLQL+ +SFALVPSLQRLMLRRVALKNVD SPSPF+PLR
Sbjct 434 LSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLR 493
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
NLTILDLSNNNIANIN+D+LEGLE LEILD QHNNLARLWK ANPGGP+ FLKGLSHLHI
Sbjct 494 NLTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWKRANPGGPVNFLKGLSHLHI 553
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
LNLESNG DEIPV VFK+LFELK I+LGLNNLN L +F++Q SL+SLNLQKNLITSVE
Sbjct 554 LNLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVE 613
Query 627 KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGF 686
K VFGP F+NL LDMRFNPFDCTCESI+WFVNWIN+THTNI ELS+HYLCNTP HY+GF
Sbjct 614 KDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGF 673
Query 687 PVRLFDTSSCK 697
P++LFDTSSCK
Sbjct 674 PLKLFDTSSCK 684
>7das_A A Toll-like receptor 3
Length=684
Score = 1015 bits (2624), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 526/672 (78%), Positives = 585/672 (87%), Gaps = 0/672 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++CTV + VADCSHLKLT +PDDLP+NITVLNLTHNQLRRLP NFTRYSQL LD GFN
Sbjct 13 SQCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFN 72
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ISKLEPELCQ LP+LKVLNLQHNELSQ+SD+TF FCTNLTEL LMSNSI KIK+NPF
Sbjct 73 SISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKN 132
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
QKNLI LDLSHNGLSSTKLGT VQLENLQELLL+ NKI AL+SEEL+ NSSL+KL+LS
Sbjct 133 QKNLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLS 192
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
SN +KEFSPGCF IG+LF L LNN QL P LTEKLC EL+NTSI+NLSL+N+QL TS
Sbjct 193 SNPLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSE 252
Query 266 TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVR 325
+TF GLKWTNLT LDLSYNNL+ VGN SF++LP L Y LEYNNIQ L S +GL N+R
Sbjct 253 STFSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLR 312
Query 326 YLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
YL+LKR+FTKQS AS P IDDFSFQWLK LE+LNM+DN+IP KSN FTGL++LKYLS
Sbjct 313 YLSLKRAFTKQSXXXASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLS 372
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS +FTSL+TLTNETFVSLAHSPL LNLTKN ISKI + FSWLG L +LDLGLNEI Q
Sbjct 373 LSKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQ 432
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+L+GQEWRGL NIFEIYLSYNKYLQL+ +SFALVPSLQRLMLRRVALKNVD SPSPF+PL
Sbjct 433 KLSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPL 492
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
RNLTILDLSNNNIANIN+D+LEGLE LEILD QHNNLARLWK ANPGGP+ FLKGLSHLH
Sbjct 493 RNLTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWKRANPGGPVNFLKGLSHLH 552
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
ILNLESNG DEIPV VFK+LFELK I+LGLNNLN L +F++Q SL+SLNLQKNLITSV
Sbjct 553 ILNLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSV 612
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
EK VFGP F+NL LDMRFNPFDCTCESI+WFVNWIN+THTNI ELS+HYLCNTP HY+G
Sbjct 613 EKDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYG 672
Query 686 FPVRLFDTSSCK 697
FP++LFDTSSCK
Sbjct 673 FPLKLFDTSSCK 684
>7wm4_B D Toll-like receptor 3
Length=680
Score = 1013 bits (2620), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 526/671 (78%), Positives = 585/671 (87%), Gaps = 0/671 (0%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+CTV + VADCSHLKLT +PDDLP+NITVLNLTHNQLRRLP NFTRYSQL LD GFN+
Sbjct 3 QCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNS 62
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
ISKLEPELCQ LP+LKVLNLQHNELSQ+SD+TF FCTNLTEL LMSNSI KIK+NPF Q
Sbjct 63 ISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQ 122
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
KNLI LDLSHNGLSSTKLGT VQLENLQELLL+ NKI AL+SEEL+ NSSL+KL+LSS
Sbjct 123 KNLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSS 182
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
N +KEFSPGCF IG+LF L LNN QL P LTEKLC EL+NTSI+NLSL+N+QL TS +
Sbjct 183 NPLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSES 242
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRY 326
TF GLKWTNLT LDLSYNNL+ VGN SF++LP L Y LEYNNIQ L S +GL N+RY
Sbjct 243 TFSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRY 302
Query 327 LNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
L+LKR+FTKQS+SLAS P IDDFSFQWLK LE+LNM+DN+IP KSN FTGL++LKYLSL
Sbjct 303 LSLKRAFTKQSVSLASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSL 362
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
S +FTSL+TLTNETFVSLAHSPL LNLTKN ISKI + FSWLG L +LDLGLNEI Q+
Sbjct 363 SKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQK 422
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
L+GQEWRGL NIFEIYLSYNKYLQL+ +SFALVPSLQRLMLRRVALKNVD SPSPF+PLR
Sbjct 423 LSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLR 482
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
NLTILDLSNNNIANIN+D+LEGLE LEILD QHNNLARLW NPGGP+ FLKGLSHLHI
Sbjct 483 NLTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWXXXNPGGPVNFLKGLSHLHI 542
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
LNLESNG DEIPV VFK+LFELK I+LGLNNLN L +F++Q SL+SLNLQKNLITSVE
Sbjct 543 LNLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVE 602
Query 627 KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGF 686
K VFGP F+NL LDMRFNPFDCTCESI+WFVNWIN+THTNI ELS+HYLCNTP HY+GF
Sbjct 603 KDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGF 662
Query 687 PVRLFDTSSCK 697
P++LFDTSSCK
Sbjct 663 PLKLFDTSSCK 673
>7das_B B Toll-like receptor 3
Length=684
Score = 1013 bits (2620), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 525/671 (78%), Positives = 584/671 (87%), Gaps = 0/671 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++CTV + VADCSHLKLT +PDDLP+NITVLNLTHNQLRRLP NFTRYSQL LD GFN
Sbjct 13 SQCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFN 72
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ISKLEPELCQ LP+LKVLNLQHNELSQ+SD+TF FCTNLTEL LMSNSI KIK+NPF
Sbjct 73 SISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKN 132
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
QKNLI LDLSHNGLSSTKLGT VQLENLQELLL+ NKI AL+SEEL+ NSSL+KL+LS
Sbjct 133 QKNLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLS 192
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
SN +KEFSPGCF IG+LF L LNN QL P LTEKLC EL+NTSI+NLSL+N+QL TS
Sbjct 193 SNPLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSE 252
Query 266 TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVR 325
+TF GLKWTNLT LDLSYNNL+ VGN SF++LP L Y LEYNNIQ L S +GL N+R
Sbjct 253 STFSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLR 312
Query 326 YLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
YL+LKR+FTKQS AS P IDDFSFQWLK LE+LNM+DN+IP KSN FTGL++LKYLS
Sbjct 313 YLSLKRAFTKQSXXXASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLS 372
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS +FTSL+TLTNETFVSLAHSPL LNLTKN ISKI + FSWLG L +LDLGLNEI Q
Sbjct 373 LSKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQ 432
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+L+GQEWRGL NIFEIYLSYNKYLQL+ +SFALVPSLQRLMLRRVALKNVD SPSPF+PL
Sbjct 433 KLSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPL 492
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
RNLTILDLSNNNIANIN+D+LEGLE LEILD QHNNLARLWK ANPGGP+ FLKGLSHLH
Sbjct 493 RNLTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWKRANPGGPVNFLKGLSHLH 552
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
ILNLESNG DEIPV VFK+LFELK I+LGLNNLN L +F++Q SL+SLNLQKNLITSV
Sbjct 553 ILNLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSV 612
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
EK VFGP F+NL LDMRFNPFDCTCESI+WFVNWIN+THTNI ELS+HYLCNTP HY+G
Sbjct 613 EKDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYG 672
Query 686 FPVRLFDTSSC 696
FP++LFDTSSC
Sbjct 673 FPLKLFDTSSC 683
>3ciy_D B Toll-like receptor 3
Length=697
Score = 1013 bits (2620), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 526/671 (78%), Positives = 585/671 (87%), Gaps = 0/671 (0%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+CTV + VADCSHLKLT +PDDLP+NITVLNLTHNQLRRLP NFTRYSQL LD GFN+
Sbjct 1 QCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNS 60
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
ISKLEPELCQ LP+LKVLNLQHNELSQ+SD+TF FCTNLTEL LMSNSI KIK+NPF Q
Sbjct 61 ISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQ 120
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
KNLI LDLSHNGLSSTKLGT VQLENLQELLL+ NKI AL+SEEL+ NSSL+KL+LSS
Sbjct 121 KNLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSS 180
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
N +KEFSPGCF IG+LF L LNN QL P LTEKLC EL+NTSI+NLSL+N+QL TS +
Sbjct 181 NPLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSES 240
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRY 326
TF GLKWTNLT LDLSYNNL+ VGN SF++LP L Y LEYNNIQ L S +GL N+RY
Sbjct 241 TFSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRY 300
Query 327 LNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
L+LKR+FTKQS+SLAS P IDDFSFQWLK LE+LNM+DN+IP KSN FTGL++LKYLSL
Sbjct 301 LSLKRAFTKQSVSLASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSL 360
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
S +FTSL+TLTNETFVSLAHSPL LNLTKN ISKI + FSWLG L +LDLGLNEI Q+
Sbjct 361 SKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQK 420
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
L+GQEWRGL NIFEIYLSYNKYLQL+ +SFALVPSLQRLMLRRVALKNVD SPSPF+PLR
Sbjct 421 LSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLR 480
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
NLTILDLSNNNIANIN+D+LEGLE LEILD QHNNLARLW NPGGP+ FLKGLSHLHI
Sbjct 481 NLTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWXXXNPGGPVNFLKGLSHLHI 540
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
LNLESNG DEIPV VFK+LFELK I+LGLNNLN L +F++Q SL+SLNLQKNLITSVE
Sbjct 541 LNLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVE 600
Query 627 KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGF 686
K VFGP F+NL LDMRFNPFDCTCESI+WFVNWIN+THTNI ELS+HYLCNTP HY+GF
Sbjct 601 KDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGF 660
Query 687 PVRLFDTSSCK 697
P++LFDTSSCK
Sbjct 661 PLKLFDTSSCK 671
>7wm4_D F Toll-like receptor 3
Length=680
Score = 1013 bits (2620), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 526/671 (78%), Positives = 585/671 (87%), Gaps = 0/671 (0%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+CTV + VADCSHLKLT +PDDLP+NITVLNLTHNQLRRLP NFTRYSQL LD GFN+
Sbjct 3 QCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNS 62
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
ISKLEPELCQ LP+LKVLNLQHNELSQ+SD+TF FCTNLTEL LMSNSI KIK+NPF Q
Sbjct 63 ISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQ 122
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
KNLI LDLSHNGLSSTKLGT VQLENLQELLL+ NKI AL+SEEL+ NSSL+KL+LSS
Sbjct 123 KNLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSS 182
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
N +KEFSPGCF IG+LF L LNN QL P LTEKLC EL+NTSI+NLSL+N+QL TS +
Sbjct 183 NPLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSES 242
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRY 326
TF GLKWTNLT LDLSYNNL+ VGN SF++LP L Y LEYNNIQ L S +GL N+RY
Sbjct 243 TFSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRY 302
Query 327 LNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
L+LKR+FTKQS+SLAS P IDDFSFQWLK LE+LNM+DN+IP KSN FTGL++LKYLSL
Sbjct 303 LSLKRAFTKQSVSLASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSL 362
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
S +FTSL+TLTNETFVSLAHSPL LNLTKN ISKI + FSWLG L +LDLGLNEI Q+
Sbjct 363 SKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQK 422
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
L+GQEWRGL NIFEIYLSYNKYLQL+ +SFALVPSLQRLMLRRVALKNVD SPSPF+PLR
Sbjct 423 LSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLR 482
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
NLTILDLSNNNIANIN+D+LEGLE LEILD QHNNLARLW NPGGP+ FLKGLSHLHI
Sbjct 483 NLTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWXXXNPGGPVNFLKGLSHLHI 542
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
LNLESNG DEIPV VFK+LFELK I+LGLNNLN L +F++Q SL+SLNLQKNLITSVE
Sbjct 543 LNLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVE 602
Query 627 KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGF 686
K VFGP F+NL LDMRFNPFDCTCESI+WFVNWIN+THTNI ELS+HYLCNTP HY+GF
Sbjct 603 KDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGF 662
Query 687 PVRLFDTSSCK 697
P++LFDTSSCK
Sbjct 663 PLKLFDTSSCK 673
>7wm4_A C Toll-like receptor 3
Length=680
Score = 1001 bits (2588), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 521/670 (78%), Positives = 578/670 (86%), Gaps = 0/670 (0%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
CTV + VADCSHLKLT +PDDLP+NITVLNLTHNQLRRLP NFTRYSQL LD GFN+I
Sbjct 4 CTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNSI 63
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
SKLEPELCQ LP+LKVLNLQHNELSQ+SD+TF FCTNLTEL LMSNSI KIK+NPF QK
Sbjct 64 SKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQK 123
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
NLI LDLSHNGLSSTKLGT VQLENLQELLL+ NKI AL+SEEL+ NSSL+KL+LSSN
Sbjct 124 NLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSSN 183
Query 208 QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTT 267
+KEFSPGCF IG+LF L LNN QL P LTEKLC EL+NTSI+NLSL+N+QL TS +T
Sbjct 184 PLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSEST 243
Query 268 FLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
F GLKWTNLT LDLSYNNL+ VGN SF++LP L Y LEYNNIQ L S +GL N+RYL
Sbjct 244 FSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRYL 303
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
+LKR+FTK S P IDDFSFQWLK LE+LNM+DN+IP KSN FTGL++LKYLSLS
Sbjct 304 SLKRAFTKXXXXXXSHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSLS 363
Query 388 NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQEL 447
+FTSL+TLTNETFVSLAHSPL LNLTKN ISKI + FSWLG L +LDLGLNEI Q+L
Sbjct 364 KTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQKL 423
Query 448 TGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRN 507
+GQEWRGL NIFEIYLSYNKYLQL+ +SFALVPSLQRLMLRRVALKNVD SPSPF+PLRN
Sbjct 424 SGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLRN 483
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
LTILDLSNNNIANIN+D+LEGLE LEILD QHNNLARLW NPGGP+ FLKGLSHLHIL
Sbjct 484 LTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWXXXNPGGPVNFLKGLSHLHIL 543
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
NLESNG DEIPV VFK+LFELK I+LGLNNLN L +F++Q SL+SLNLQKNLITSVEK
Sbjct 544 NLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVEK 603
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGP F+NL LDMRFNPFDCTCESI+WFVNWIN+THTNI ELS+HYLCNTP HY+GFP
Sbjct 604 DVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGFP 663
Query 688 VRLFDTSSCK 697
++LFDTSSCK
Sbjct 664 LKLFDTSSCK 673
>3ciy_C A Toll-like receptor 3
Length=697
Score = 1001 bits (2588), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 521/670 (78%), Positives = 578/670 (86%), Gaps = 0/670 (0%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
CTV + VADCSHLKLT +PDDLP+NITVLNLTHNQLRRLP NFTRYSQL LD GFN+I
Sbjct 2 CTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNSI 61
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
SKLEPELCQ LP+LKVLNLQHNELSQ+SD+TF FCTNLTEL LMSNSI KIK+NPF QK
Sbjct 62 SKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQK 121
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
NLI LDLSHNGLSSTKLGT VQLENLQELLL+ NKI AL+SEEL+ NSSL+KL+LSSN
Sbjct 122 NLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSSN 181
Query 208 QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTT 267
+KEFSPGCF IG+LF L LNN QL P LTEKLC EL+NTSI+NLSL+N+QL TS +T
Sbjct 182 PLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSEST 241
Query 268 FLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
F GLKWTNLT LDLSYNNL+ VGN SF++LP L Y LEYNNIQ L S +GL N+RYL
Sbjct 242 FSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRYL 301
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
+LKR+FTK S P IDDFSFQWLK LE+LNM+DN+IP KSN FTGL++LKYLSLS
Sbjct 302 SLKRAFTKXXXXXXSHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSLS 361
Query 388 NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQEL 447
+FTSL+TLTNETFVSLAHSPL LNLTKN ISKI + FSWLG L +LDLGLNEI Q+L
Sbjct 362 KTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQKL 421
Query 448 TGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRN 507
+GQEWRGL NIFEIYLSYNKYLQL+ +SFALVPSLQRLMLRRVALKNVD SPSPF+PLRN
Sbjct 422 SGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLRN 481
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
LTILDLSNNNIANIN+D+LEGLE LEILD QHNNLARLW NPGGP+ FLKGLSHLHIL
Sbjct 482 LTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWXXXNPGGPVNFLKGLSHLHIL 541
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
NLESNG DEIPV VFK+LFELK I+LGLNNLN L +F++Q SL+SLNLQKNLITSVEK
Sbjct 542 NLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVEK 601
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGP F+NL LDMRFNPFDCTCESI+WFVNWIN+THTNI ELS+HYLCNTP HY+GFP
Sbjct 602 DVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGFP 661
Query 688 VRLFDTSSCK 697
++LFDTSSCK
Sbjct 662 LKLFDTSSCK 671
>7wm4_C E Toll-like receptor 3
Length=680
Score = 1001 bits (2588), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 521/670 (78%), Positives = 578/670 (86%), Gaps = 0/670 (0%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
CTV + VADCSHLKLT +PDDLP+NITVLNLTHNQLRRLP NFTRYSQL LD GFN+I
Sbjct 4 CTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNSI 63
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
SKLEPELCQ LP+LKVLNLQHNELSQ+SD+TF FCTNLTEL LMSNSI KIK+NPF QK
Sbjct 64 SKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQK 123
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
NLI LDLSHNGLSSTKLGT VQLENLQELLL+ NKI AL+SEEL+ NSSL+KL+LSSN
Sbjct 124 NLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSSN 183
Query 208 QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTT 267
+KEFSPGCF IG+LF L LNN QL P LTEKLC EL+NTSI+NLSL+N+QL TS +T
Sbjct 184 PLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSEST 243
Query 268 FLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
F GLKWTNLT LDLSYNNL+ VGN SF++LP L Y LEYNNIQ L S +GL N+RYL
Sbjct 244 FSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRYL 303
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
+LKR+FTK S P IDDFSFQWLK LE+LNM+DN+IP KSN FTGL++LKYLSLS
Sbjct 304 SLKRAFTKXXXXXXSHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSLS 363
Query 388 NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQEL 447
+FTSL+TLTNETFVSLAHSPL LNLTKN ISKI + FSWLG L +LDLGLNEI Q+L
Sbjct 364 KTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQKL 423
Query 448 TGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRN 507
+GQEWRGL NIFEIYLSYNKYLQL+ +SFALVPSLQRLMLRRVALKNVD SPSPF+PLRN
Sbjct 424 SGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLRN 483
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
LTILDLSNNNIANIN+D+LEGLE LEILD QHNNLARLW NPGGP+ FLKGLSHLHIL
Sbjct 484 LTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWXXXNPGGPVNFLKGLSHLHIL 543
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
NLESNG DEIPV VFK+LFELK I+LGLNNLN L +F++Q SL+SLNLQKNLITSVEK
Sbjct 544 NLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVEK 603
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFP 687
VFGP F+NL LDMRFNPFDCTCESI+WFVNWIN+THTNI ELS+HYLCNTP HY+GFP
Sbjct 604 DVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGFP 663
Query 688 VRLFDTSSCK 697
++LFDTSSCK
Sbjct 664 LKLFDTSSCK 673
>3cig_A A Toll-like receptor 3
Length=697
Score = 999 bits (2582), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 521/671 (78%), Positives = 580/671 (86%), Gaps = 0/671 (0%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+CTV + VADCSHLKLT +PDDLP+NITVLNLTHNQLRRLP NFTRYSQL LD GFN+
Sbjct 1 QCTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQLAILDAGFNS 60
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
ISKLEPELCQ LP+LKVLNLQHNELSQ+SD+TF FCTNLTEL LMSNSI KIK+NPF Q
Sbjct 61 ISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTELDLMSNSIHKIKSNPFKNQ 120
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
KNLI LDLSHNGLSSTKLGT VQLENLQELLL+ NKI AL+SEEL+ NSSL+KL+LSS
Sbjct 121 KNLIKLDLSHNGLSSTKLGTGVQLENLQELLLAKNKILALRSEELEFLGNSSLRKLDLSS 180
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
N +KEFSPGCF IG+LF L LNN QL P LTEKLC EL+NTSI+NLSL+N+QL TS +
Sbjct 181 NPLKEFSPGCFQTIGKLFALLLNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSES 240
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRY 326
TF GLKWTNLT LDLSYNNL+ VGN SF++LP L Y LEYNNIQ L S +GL N+RY
Sbjct 241 TFSGLKWTNLTQLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRY 300
Query 327 LNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
L+LKR+FTKQS+SLAS P IDDFSFQWLK LE+LNM+DN+IP KSN FTGL++LKYLSL
Sbjct 301 LSLKRAFTKQSVSLASHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKYLSL 360
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
S +FTSL+TLTNETFVSLAHSPL LNLTKN ISKI + FSWLG L +LDLGLNEI Q+
Sbjct 361 SKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQLRILDLGLNEIEQK 420
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
L+GQEWRGL NIFEIYLSYNKYLQL+ +SFALVPSLQRLMLRRVALKNVD SPSPF+PLR
Sbjct 421 LSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQRLMLRRVALKNVDISPSPFRPLR 480
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
NLTILDLSNNNIANIN+D+LEGLE LEILD QHNNLARLW + FLKGLSHLHI
Sbjct 481 NLTILDLSNNNIANINEDLLEGLENLEILDFQHNNLARLWXXXXXXXXVNFLKGLSHLHI 540
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
LNLESNG DEIPV VFK+LFELK I+LGLNNLN L +F++Q SL+SLNLQKNLITSVE
Sbjct 541 LNLESNGLDEIPVGVFKNLFELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVE 600
Query 627 KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGF 686
K VFGP F+NL LDMRFNPFDCTCESI+WFVNWIN+THTNI ELS+HYLCNTP HY+GF
Sbjct 601 KDVFGPPFQNLNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGF 660
Query 687 PVRLFDTSSCK 697
P++LFDTSSCK
Sbjct 661 PLKLFDTSSCK 671
>4r6f_A A Leucine rich repeat DLRR_I
Length=331
Score = 181 bits (458), Expect = 3e-49, Method: Compositional matrix adjust.
Identities = 129/313 (41%), Positives = 169/313 (54%), Gaps = 30/313 (10%)
Query 328 NLKRSFTKQSISLASLPKIDDF-----------SFQWLKCLEHLNMEDN---DIPGIKSN 373
NLK+ +++ L ID Q+L + +L + N DI +K
Sbjct 25 NLKKKSVTDAVTQNELNSIDQIIANNSDIKSVQGIQYLPNVRYLALGGNKLHDISALKE- 83
Query 374 MFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHL 433
L NL +L+LSN+ L TL F L + L LNL+ N+++ + F L L
Sbjct 84 ----LTNLGWLNLSNN--QLETLPQGVFEKLTN--LTTLNLSNNQLTSLPQGVFERLASL 135
Query 434 EVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP-----SLQRLMLR 488
L+L N I + Q GL N+ + LS+N +L +++ P L L
Sbjct 136 TTLNLSNNNIAN-INDQMLEGLTNLTTLNLSHNNLARLWKHANPGGPIYFLKGLTNLTTL 194
Query 489 RVALKNVDSSPSP-FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
++ D P F+ L +LT L+LSNNNIANIND MLEGL L L+L HNNLARLWK
Sbjct 195 NLSSNGFDEIPREVFKDLTSLTTLNLSNNNIANINDQMLEGLTNLTTLNLSHNNLARLWK 254
Query 548 HANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
HANPGGPIYFLKGL++L LNL SNGFDEIP EVFKDL L ++L N L +LP VF
Sbjct 255 HANPGGPIYFLKGLTNLTTLNLSSNGFDEIPREVFKDLTSLTTLNLSNNQLTSLPQGVFE 314
Query 608 NQVSLKSLNLQKN 620
+LK+LNL N
Sbjct 315 RLTNLKTLNLSNN 327
Score = 150 bits (379), Expect = 1e-38, Method: Compositional matrix adjust.
Identities = 105/242 (43%), Positives = 137/242 (57%), Gaps = 23/242 (10%)
Query 420 SKIES-DAFSWLGHLEVLDLGLNEIG-----QELTGQEWRGLENIFEIYLSYNKYLQLTR 473
S I+S +L ++ L LG N++ +ELT W + LS N+ L +
Sbjct 51 SDIKSVQGIQYLPNVRYLALGGNKLHDISALKELTNLGW--------LNLSNNQLETLPQ 102
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
F + +L L L L ++ F+ L +LT L+LSNNNIANIND MLEGL L
Sbjct 103 GVFEKLTNLTTLNLSNNQLTSLPQGV--FERLASLTTLNLSNNNIANINDQMLEGLTNLT 160
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
L+L HNNLARLWKHANPGGPIYFLKGL++L LNL SNGFDEIP EVFKDL L ++L
Sbjct 161 TLNLSHNNLARLWKHANPGGPIYFLKGLTNLTTLNLSSNGFDEIPREVFKDLTSLTTLNL 220
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV--FGPAF-----RNLTELDMRFNP 646
NN+ + + +L +LNL N + + K GP + NLT L++ N
Sbjct 221 SNNNIANINDQMLEGLTNLTTLNLSHNNLARLWKHANPGGPIYFLKGLTNLTTLNLSSNG 280
Query 647 FD 648
FD
Sbjct 281 FD 282
Score = 73.2 bits (178), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 84/251 (33%), Positives = 129/251 (51%), Gaps = 21/251 (8%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ LNL++NQL LP F + + LT+L++ N ++ L + ++L L LNL +N
Sbjct 85 TNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNN 144
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKI--KNNP-----FVKQ-KNLITLDLSHNGLSST 162
++ ++D+ TNLT L+L N++ ++ NP F+K NL TL+LS NG
Sbjct 145 IANINDQMLEGLTNLTTLNLSHNNLARLWKHANPGGPIYFLKGLTNLTTLNLSSNGFDEI 204
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI----KEFSPGCFH 218
L +L L LSNN I + + L+ N L L LS N + K +PG
Sbjct 205 PREVFKDLTSLTTLNLSNNNIANINDQMLEGLTN--LTTLNLSHNNLARLWKHANPGG-- 260
Query 219 AIGRLFGLF-LNNVQLGPSLTEKLCLELAN--TSIRNLSLSNSQLSTTSNTTFLGLKWTN 275
I L GL L + L + +++ E+ TS+ L+LSN+QL++ F + TN
Sbjct 261 PIYFLKGLTNLTTLNLSSNGFDEIPREVFKDLTSLTTLNLSNNQLTSLPQGVF--ERLTN 318
Query 276 LTMLDLSYNNL 286
L L+LS N L
Sbjct 319 LKTLNLSNNQL 329
Score = 67.0 bits (162), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 51/142 (36%), Positives = 75/142 (53%), Gaps = 8/142 (6%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T LNL+ N +P F + LT+L++ N I+ + ++ + L L LNL HN
Sbjct 189 TNLTTLNLSSNGFDEIPREVFKDLTSLTTLNLSNNNIANINDQMLEGLTNLTTLNLSHNN 248
Query 111 LSQLSDKT--------FAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSST 162
L++L TNLT L+L SN +I F +L TL+LS+N L+S
Sbjct 249 LARLWKHANPGGPIYFLKGLTNLTTLNLSSNGFDEIPREVFKDLTSLTTLNLSNNQLTSL 308
Query 163 KLGTQVQLENLQELLLSNNKIQ 184
G +L NL+ L LSNN++Q
Sbjct 309 PQGVFERLTNLKTLNLSNNQLQ 330
Score = 59.3 bits (142), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 87/306 (28%), Positives = 140/306 (46%), Gaps = 70/306 (23%)
Query 170 LENLQELLLSNNKIQALKS-EELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
L N++ L L NK+ + + +EL ++L L LS+NQ++ G F + L L L
Sbjct 62 LPNVRYLALGGNKLHDISALKEL-----TNLGWLNLSNNQLETLPQGVFEKLTNLTTLNL 116
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
+N QL SL + + LA S+ L+LSN+ ++ ++ GL TNLT L+LS+NNL
Sbjct 117 SNNQL-TSLPQGVFERLA--SLTTLNLSNNNIANINDQMLEGL--TNLTTLNLSHNNL-- 169
Query 289 VGNDSFAWL---PQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
+ W P +FL+ GL N+ LNL + +
Sbjct 170 ----ARLWKHANPGGPIYFLK-------------GLTNLTTLNLSSN---------GFDE 203
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS------------- 392
I F+ L L LN+ +N+I I M GL NL L+LS++ +
Sbjct 204 IPREVFKDLTSLTTLNLSNNNIANINDQMLEGLTNLTTLNLSHNNLARLWKHANPGGPIY 263
Query 393 -LRTLTNETFVSLAH--------------SPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
L+ LTN T ++L+ + L LNL+ N+++ + F L +L+ L+
Sbjct 264 FLKGLTNLTTLNLSSNGFDEIPREVFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLKTLN 323
Query 438 LGLNEI 443
L N++
Sbjct 324 LSNNQL 329
Score = 55.1 bits (131), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 84/303 (28%), Positives = 129/303 (43%), Gaps = 66/303 (22%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
++L L LNL +N+L L F TNLT L+L +N + + F + +L TL+LS
Sbjct 82 KELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLS 141
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQAL---KSEELDIF---ANSSLKKLELSSNQI 209
+N +++ L NL L LS+N + L + I+ ++L L LSSN
Sbjct 142 NNNIANINDQMLEGLTNLTTLNLSHNNLARLWKHANPGGPIYFLKGLTNLTTLNLSSNGF 201
Query 210 KEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFL 269
E F + TS+ L+LSN+ ++ ++
Sbjct 202 DEIPREVFKDL---------------------------TSLTTLNLSNNNIANINDQMLE 234
Query 270 GLKWTNLTMLDLSYNNLNVVGNDSFAWL---PQLEYFFLEYNNIQHLFSHSLHGLFNVRY 326
GL TNLT L+LS+NNL + W P +FL+ GL N+
Sbjct 235 GL--TNLTTLNLSHNNL------ARLWKHANPGGPIYFLK-------------GLTNLTT 273
Query 327 LNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
LNL + +I F+ L L LN+ +N + + +F L NLK L+L
Sbjct 274 LNLSSN---------GFDEIPREVFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLKTLNL 324
Query 387 SNS 389
SN+
Sbjct 325 SNN 327
>3j0a_A A Toll-like receptor 5
Length=844
Score = 152 bits (384), Expect = 2e-36, Method: Compositional matrix adjust.
Identities = 193/805 (24%), Positives = 309/805 (38%), Gaps = 179/805 (22%)
Query 199 LKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNS 258
L+ L+L S++I P F + LF L L L ++ L + RNL
Sbjct 75 LRILDLGSSKIYFLHPDAFQGLFHLFELRLYFCGLSDAV-------LKDGYFRNLKA--- 124
Query 259 QLSTTSNTTFLGLKWTNLTMLDLSYNNL-NVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
LT LDLS N + ++ + SF L L+ N I + H
Sbjct 125 -----------------LTRLDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQIFLVCEHE 167
Query 318 LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKC--------LEHLNMEDN---- 365
L L + T SLA+ S W KC LE L++ N
Sbjct 168 LEPL---------QGKTLSFFSLAANSLYSRVSVDWGKCMNPFRNMVLEILDVSGNGWTV 218
Query 366 DIPG------IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
DI G KS F+ ++ + F +++ TF LA S + L+L+ +
Sbjct 219 DITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFV 278
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALV 479
+ S F L L+VL+L N+I + + + + GL+N+ + LSYN +L ++F +
Sbjct 279 FSLNSRVFETLKDLKVLNLAYNKINK-IADEAFYGLDNLQVLNLSYNLLGELYSSNFYGL 337
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
P + +DL N+IA I D + LEKL+ LDL+
Sbjct 338 PKV--------------------------AYIDLQKNHIAIIQDQTFKFLEKLQTLDLRD 371
Query 540 NNLARLWKHANPGGP----------------------------------IYFLKGLSHLH 565
N L + H P P +YFL + HL
Sbjct 372 NALTTI--HFIPSIPDIFLSGNKLVTLPKINLTANLIHLSENRLENLDILYFLLRVPHLQ 429
Query 566 ILNLESNGF-----DEIPVE-------------------------VFKDLFELKIIDLGL 595
IL L N F D+ P E VF+ L L+++ L
Sbjct 430 ILILNQNRFSSCSGDQTPSENPSLEQLFLGENMLQLAWETELCWDVFEGLSHLQVLYLNH 489
Query 596 NNLNTLPASVFNNQVSLKSLNLQKNLITSV---------------EKKVFGP---AFRNL 637
N LN+LP VF++ +L+ L+L N +T + ++ P F +L
Sbjct 490 NYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHNDLPANLEILDISRNQLLAPNPDVFVSL 549
Query 638 TELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSCK 697
+ LD+ N F C CE ++ F+NW+N T+ I + C P + G + T C
Sbjct 550 SVLDITHNKFICECE-LSTFINWLNHTNVTIAGPPADIYCVYPDSFSGVSLFSLSTEGCX 608
Query 698 DSAP-----FELFFMINTSILLIFIFIVLLIHFEGWRISFYWNVSVHRVLGFKEIDRQTE 752
F LF + ++ L + I+ + F + + +
Sbjct 609 XXXXXXXXXFSLFIVCTVTLTLFLMTILTVTKFRXXXXXXXXXXXXXXXXDHPQ-GTEPD 667
Query 753 QFEYAAYIIHAYKDKDWV----WEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIK 808
++Y AY+ + KD WV +H + + C EERDF G + I ++I
Sbjct 668 MYKYDAYLCFSSKDFTWVQNALLKHLDTQYSDQNRFNLCFEERDFVPGENRIANIQDAIW 727
Query 809 RSRKIIFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRR 868
SRKI+ +++ H L+D C +A + + ++I+V + + Y+L + R
Sbjct 728 NSRKIVCLVSRHFLRDGWCLE-AFSYAQGRCLSDLNSALIMVVVGSLSQYQLMKHQSI-R 785
Query 869 GMFKSHCILNWPVQKERIGAFRHKL 893
G + L WP + +G F HKL
Sbjct 786 GFVQKQQYLRWPEDFQDVGWFLHKL 810
Score = 82.8 bits (203), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 148/567 (26%), Positives = 244/567 (43%), Gaps = 65/567 (11%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN-T 86
C+ +A LTQVP L T +L L+ N +R + A++F QL L++G T
Sbjct 2 CSFDGRIAFYRFCNLTQVPQVLNTTERLL-LSFNYIRTVTASSFPFLEQLQLLELGSQYT 60
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL----MSNSIQKIKNNP 142
++ E + LP L++L+L +++ L F +L EL L +S+++ +K+
Sbjct 61 PLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQGLFHLFELRLYFCGLSDAV--LKDGY 118
Query 143 FVKQKNLITLDLSHNGLSSTKLGTQV-QLENLQELLLSNNKIQALKSEELDIFANSSLKK 201
F K L LDLS N + S L +L +L+ + S+N+I + EL+ +L
Sbjct 119 FRNLKALTRLDLSKNQIRSLYLHPSFGKLNSLKSIDFSSNQIFLVCEHELEPLQGKTLSF 178
Query 202 LELSSNQIKEFSP----GCFHAIGRLFGLFLN------------NVQLGPSLTEKLCLEL 245
L++N + C + + L+ N S ++ L L
Sbjct 179 FSLAANSLYSRVSVDWGKCMNPFRNMVLEILDVSGNGWTVDITGNFSNAISKSQAFSLIL 238
Query 246 ANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFL 305
A+ I + TF GL +++ LDLS+ + + + F L L+ L
Sbjct 239 AH-HIMGAGFGFHNIKDPDQNTFAGLARSSVRHLDLSHGFVFSLNSRVFETLKDLKVLNL 297
Query 306 EYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQ--SISLASLPK-------------IDDFS 350
YN I + + +GL N++ LNL + + S + LPK I D +
Sbjct 298 AYNKINKIADEAFYGLDNLQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQT 357
Query 351 FQWLKCLEHLNMEDND------IPGIKSNMFTG--LINLKYLSLSNSFTSL---RTLTNE 399
F++L+ L+ L++ DN IP I +G L+ L ++L+ + L R +
Sbjct 358 FKFLEKLQTLDLRDNALTTIHFIPSIPDIFLSGNKLVTLPKINLTANLIHLSENRLENLD 417
Query 400 TFVSLAHSP-LHILNLTKNKISKIESDAF-SWLGHLEVLDLGLNEIG----QELTGQEWR 453
L P L IL L +N+ S D S LE L LG N + EL +
Sbjct 418 ILYFLLRVPHLQILILNQNRFSSCSGDQTPSENPSLEQLFLGENMLQLAWETELCWDVFE 477
Query 454 GLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDL 513
GL ++ +YL++N L F+ + +L+ L L L + + P NL ILD+
Sbjct 478 GLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHNDLP----ANLEILDI 533
Query 514 SNNNIANINDDMLEGLEKLEILDLQHN 540
S N + N D+ L +LD+ HN
Sbjct 534 SRNQLLAPNPDV---FVSLSVLDITHN 557
Score = 62.0 bits (149), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 81/306 (26%), Positives = 137/306 (45%), Gaps = 33/306 (11%)
Query 17 FGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQ 76
F L SS +SH + ++ + DL VLNL +N++ ++ F
Sbjct 260 FAGLARSSVRHLDLSHGFVFSLNSRVFETLKDL----KVLNLAYNKINKIADEAFYGLDN 315
Query 77 LTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ 136
L L++ +N + +L LP + ++LQ N ++ + D+TF F L L L N++
Sbjct 316 LQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALT 375
Query 137 KIKNNP-----FVKQKNLITLD----------LSHNGLSSTK-LGTQVQLENLQELLLSN 180
I P F+ L+TL LS N L + L +++ +LQ L+L+
Sbjct 376 TIHFIPSIPDIFLSGNKLVTLPKINLTANLIHLSENRLENLDILYFLLRVPHLQILILNQ 435
Query 181 NKIQALKSEELDIFANSSLKKLELSSNQIK-----EFSPGCFHAIGRLFGLFLNNVQLGP 235
N+ + ++ N SL++L L N ++ E F + L L+LN+ L
Sbjct 436 NRFSSCSGDQTPS-ENPSLEQLFLGENMLQLAWETELCWDVFEGLSHLQVLYLNHNYLN- 493
Query 236 SLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
SL + L T++R LSL++++L+ S+ NL +LD+S N L D F
Sbjct 494 SLPPGVFSHL--TALRGLSLNSNRLTVLSHNDLPA----NLEILDISRNQLLAPNPDVFV 547
Query 296 WLPQLE 301
L L+
Sbjct 548 SLSVLD 553
>7wrq_A A Insulin-like growth factor-binding protein complex acid
labile subunit
Length=578
Score = 136 bits (343), Expect = 4e-32, Method: Compositional matrix adjust.
Identities = 150/539 (28%), Positives = 238/539 (44%), Gaps = 66/539 (12%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
CS LT++PD +P L L N L +P A F S L L++ + LEP+
Sbjct 33 CSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGSLEPQALL 92
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L+L+ N+L L+ TFA L L L +N + ++++ F +L L+L
Sbjct 93 GLENLCHLHLERNQLRSLALGTFAHTPALASLGLSNNRLSRLEDGLFEGLGSLWDLNLGW 152
Query 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGC 216
N L+ L +L+EL+L+ N++ L+ A L++L+LS N ++
Sbjct 153 NSLAVLPDAAFRGLGSLRELVLAGNRLAYLQPALFSGLA--ELRELDLSRNALRAIKANV 210
Query 217 FHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNL 276
F + RL L+L+ RNL ++ + FLGLK L
Sbjct 211 FVQLPRLQKLYLD---------------------RNL------IAAVAPGAFLGLK--AL 241
Query 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQ 336
LDLS+N + + D+F L L L +N I L + L + L L + +Q
Sbjct 242 RWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQ 301
Query 337 SISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTL 396
+ + SF+ L LE L ++ N + +K+ F GL N+ ++LS + LR L
Sbjct 302 ---------LAERSFEGLGQLEVLTLDHNQLQEVKAGAFLGLTNVAVMNLSGN--CLRNL 350
Query 397 TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVL---DLGLNEIGQELTGQEWR 453
+ F L LH L+L + + +I F+ L L L D GL I + Q
Sbjct 351 PEQVFRGLGK--LHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEE----QSLW 404
Query 454 GLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDL 513
GL + E+ L+ N+ L F + L+ L+L R L + + PL+ LD+
Sbjct 405 GLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPA--DALGPLQRAFWLDV 462
Query 514 SNNNIANINDDMLEGLEKLEILDLQHN----------NLARLWKHANP---GGPIYFLK 559
S+N + + + +L L +L L L++N L RLW NP G P+ L+
Sbjct 463 SHNRLEALPNSLLAPLGRLRYLSLRNNSLRTFTPQPPGLERLWLEGNPWDCGCPLKALR 521
Score = 127 bits (318), Expect = 5e-29, Method: Compositional matrix adjust.
Identities = 167/607 (28%), Positives = 249/607 (41%), Gaps = 96/607 (16%)
Query 115 SDKTFAFCT--NLTELH-----------LMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
+D+ FC+ NLT L L N++ + F +L L+L L S
Sbjct 26 ADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSVPPAAFQNLSSLGFLNLQGGQLGS 85
Query 162 TKLGTQVQLENLQELLLSNNKIQALKSEELDIFANS-SLKKLELSSNQIKEFSPGCFHAI 220
+ + LENL L L N++++L L FA++ +L L LS+N++ G F +
Sbjct 86 LEPQALLGLENLCHLHLERNQLRSLA---LGTFAHTPALASLGLSNNRLSRLEDGLFEGL 142
Query 221 GRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
G L+ L L N++ + P + S+R L L+ ++L+ F GL L
Sbjct 143 GSLWDLNLGWNSLAVLPDAAFR-----GLGSLRELVLAGNRLAYLQPALFSGL--AELRE 195
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDLS N L + + F LP+L+ +L+ N I
Sbjct 196 LDLSRNALRAIKANVFVQLPRLQKLYLDRNLIA--------------------------- 228
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLT 397
+ +F LK L L++ N + G+ + F GL+ L+ L LS N+ SLR
Sbjct 229 ------AVAPGAFLGLKALRWLDLSHNRVAGLLEDTFPGLLGLRVLRLSHNAIASLRP-- 280
Query 398 NETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN 457
TF L L L L N+I ++ +F LG LEVL L N++ QE+ + GL N
Sbjct 281 -RTFKDLHF--LEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQL-QEVKAGAFLGLTN 336
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
+ + LS N L F + L L L L + P F L L L L +N
Sbjct 337 VAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRI--RPHTFTGLSGLRRLFLKDNG 394
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI 577
+ I + L GL +L LDL N L L P +GL L L L N E+
Sbjct 395 LVGIEEQSLWGLAELLELDLTSNQLTHL--------PHRLFQGLGKLEYLLLSRNRLAEL 446
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNL 637
P + L +D+ N L LP S+ L+ L+L+ N + + F P L
Sbjct 447 PADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSL-----RTFTPQPPGL 501
Query 638 TELDMRFNPFDCTC-------------ESIAWFVNWINETHTNIPELSSH--YLCNTPPH 682
L + NP+DC C ++ FV I E P ++ C +PP
Sbjct 502 ERLWLEGNPWDCGCPLKALRDFALQNPSAVPRFVQAICEGDDCQPPAYTYNNITCASPPE 561
Query 683 YHGFPVR 689
G +R
Sbjct 562 VVGLDLR 568
>4r6g_A A leucine rich repeats DLRR_K
Length=464
Score = 132 bits (333), Expect = 2e-31, Method: Compositional matrix adjust.
Identities = 90/212 (42%), Positives = 117/212 (55%), Gaps = 29/212 (14%)
Query 462 YLSYNKYLQLTRNSFALVPSLQRLM-LRRVALKNVDSSPSP---FQPLRNLTILDLSNNN 517
YL +YL L N + +L+ L L + L N P F+ L NLT L+LSNN
Sbjct 60 YLPNVRYLALGGNKLHDISALKELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQ 119
Query 518 IANI------------------------NDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ ++ ND + EGL L L+L +NNLARLWKHANPGG
Sbjct 120 LTSLPQGVFERLASLTTLNLSNNNLANLNDRVFEGLTNLTTLNLSNNNLARLWKHANPGG 179
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
PIYFLKGL++L LNL +NGFDE+P EVFKDL L ++L N L +LP VF +L
Sbjct 180 PIYFLKGLTNLTTLNLSNNGFDELPKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLT 239
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
+LNL N +TS+ + VF NLT L++ N
Sbjct 240 TLNLSNNQLTSLPQGVF-ERLTNLTTLNLSNN 270
Score = 77.4 bits (189), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 73/223 (33%), Positives = 114/223 (51%), Gaps = 16/223 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T LNL++N LP F + LT+L++ N ++ L + ++L L LNL +N+
Sbjct 188 TNLTTLNLSNNGFDELPKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLTTLNLSNNQ 247
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L+ L F TNLT L+L +N + + F + +L TL+LS+N L+S G +L
Sbjct 248 LTSLPQGVFERLTNLTTLNLSNNQLTSLPQGVFERLTSLTTLNLSNNQLTSLPKGVLERL 307
Query 171 ENLQELLLSNNKIQALKSEELD--IFANSSLKKLELSSNQI-----KEFSPGCFHAIGRL 223
NL+ L LSNN+I + + +SL +L LS+N I E H L
Sbjct 308 TNLKTLNLSNNQITKEVCRHVAELLKQAASLHELHLSNNNIGEEGAAELVEALLHPGSTL 367
Query 224 FGLFLNNVQLGPSLTEKLCLELAN-----TSIRNLSLSNSQLS 261
L L+N +LT++ C E+A T++ L LSN+ +
Sbjct 368 ETLDLSNC----NLTKEACREIARALKQATTLHELHLSNNNIG 406
Score = 71.6 bits (174), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 86/242 (36%), Positives = 130/242 (54%), Gaps = 15/242 (6%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ LNL++NQL LP F + + LT+L++ N ++ L + ++L L LNL +N
Sbjct 84 TNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNN 143
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKI--KNNP-----FVKQ-KNLITLDLSHNGLSST 162
L+ L+D+ F TNLT L+L +N++ ++ NP F+K NL TL+LS+NG
Sbjct 144 LANLNDRVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNNGFDEL 203
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGR 222
L +L L LSNN++ +L + N L L LS+NQ+ G F +
Sbjct 204 PKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTN--LTTLNLSNNQLTSLPQGVFERLTN 261
Query 223 LFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLS 282
L L L+N QL SL + + L TS+ L+LSN+QL++ + TNL L+LS
Sbjct 262 LTTLNLSNNQL-TSLPQGVFERL--TSLTTLNLSNNQLTSLPKGVL--ERLTNLKTLNLS 316
Query 283 YN 284
N
Sbjct 317 NN 318
Score = 50.4 bits (119), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 76/248 (31%), Positives = 108/248 (44%), Gaps = 41/248 (17%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK-------- 147
++L L LNL +N+L L F TNLT L+L +N + + F +
Sbjct 81 KELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLS 140
Query 148 ----------------NLITLDLSHNGLSS----TKLGTQV----QLENLQELLLSNNKI 183
NL TL+LS+N L+ G + L NL L LSNN
Sbjct 141 NNNLANLNDRVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNNGF 200
Query 184 QALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLC 242
L E +F + +SL L LS+NQ+ G F + L L L+N QL SL + +
Sbjct 201 DELPKE---VFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLTTLNLSNNQL-TSLPQGVF 256
Query 243 LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
L N + L+LSN+QL++ F + T+LT L+LS N L + L L+
Sbjct 257 ERLTN--LTTLNLSNNQLTSLPQGVF--ERLTSLTTLNLSNNQLTSLPKGVLERLTNLKT 312
Query 303 FFLEYNNI 310
L N I
Sbjct 313 LNLSNNQI 320
>4r6j_C C Lucine rich repeats DLRR_H
Length=254
Score = 124 bits (312), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 83/192 (43%), Positives = 106/192 (55%), Gaps = 28/192 (15%)
Query 462 YLSYNKYLQLTRNSFALVPSLQRLM-LRRVALKNVDSSPSP---FQPLRNLTILDLSNNN 517
YL +YL L N + +L+ L L + L N P F+ L NLT L+LSNN
Sbjct 60 YLPNVRYLALGGNKLHDISALKELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQ 119
Query 518 IANI------------------------NDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ ++ ND + EGL L L+L +NNLARLWKHANPGG
Sbjct 120 LTSLPQGVFERLASLTTLNLSNNNLANLNDKVFEGLTNLTTLNLSNNNLARLWKHANPGG 179
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
PIYFLKGL++L LNL +NGFDE P EVFKDL L ++L N L +LP VF +LK
Sbjct 180 PIYFLKGLTNLTTLNLSNNGFDEFPKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLK 239
Query 614 SLNLQKNLITSV 625
+LNL N + S+
Sbjct 240 TLNLSNNQLQSL 251
Score = 59.3 bits (142), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 62/170 (36%), Positives = 95/170 (56%), Gaps = 10/170 (6%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ LNL++NQL LP F + + LT+L++ N ++ L + ++L L LNL +N
Sbjct 84 TNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNN 143
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKI--KNNP-----FVKQ-KNLITLDLSHNGLSST 162
L+ L+DK F TNLT L+L +N++ ++ NP F+K NL TL+LS+NG
Sbjct 144 LANLNDKVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNNGFDEF 203
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L +L L LSNN++ +L + N LK L LS+NQ++
Sbjct 204 PKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTN--LKTLNLSNNQLQSL 251
Score = 55.8 bits (133), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 53/146 (36%), Positives = 81/146 (55%), Gaps = 8/146 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T LNL++NQL LP F R + LT+L++ N ++ L ++ + L L LNL +N
Sbjct 108 TNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNNLANLNDKVFEGLTNLTTLNLSNNN 167
Query 111 LSQLSDKT--------FAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSST 162
L++L TNLT L+L +N + F +L TL+LS+N L+S
Sbjct 168 LARLWKHANPGGPIYFLKGLTNLTTLNLSNNGFDEFPKEVFKDLTSLTTLNLSNNQLTSL 227
Query 163 KLGTQVQLENLQELLLSNNKIQALKS 188
G +L NL+ L LSNN++Q+L +
Sbjct 228 PQGVFERLTNLKTLNLSNNQLQSLPT 253
Score = 38.1 bits (87), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 51/171 (30%), Positives = 71/171 (42%), Gaps = 36/171 (21%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK-------- 147
++L L LNL +N+L L F TNLT L+L +N + + F +
Sbjct 81 KELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLS 140
Query 148 ----------------NLITLDLSHNGLSS----TKLGTQV----QLENLQELLLSNNKI 183
NL TL+LS+N L+ G + L NL L LSNN
Sbjct 141 NNNLANLNDKVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNNGF 200
Query 184 QALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
E +F + +SL L LS+NQ+ G F + L L L+N QL
Sbjct 201 DEFPKE---VFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLKTLNLSNNQL 248
Score = 37.4 bits (85), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 50/172 (29%), Positives = 69/172 (40%), Gaps = 49/172 (28%)
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVV----------------------- 289
L+LSN+QL T F K TNLT L+LS N L +
Sbjct 89 LNLSNNQLETLPQGVFE--KLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNNLAN 146
Query 290 -GNDSFAWLPQLEYFFLEYNNIQHLFSHS--------LHGLFNVRYLNLKRSFTKQSISL 340
+ F L L L NN+ L+ H+ L GL N+ LNL +
Sbjct 147 LNDKVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNN-------- 198
Query 341 ASLPKIDDFS---FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
D+F F+ L L LN+ +N + + +F L NLK L+LSN+
Sbjct 199 ----GFDEFPKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLKTLNLSNN 246
>4r6j_B B Lucine rich repeats DLRR_H
Length=254
Score = 124 bits (312), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 83/192 (43%), Positives = 106/192 (55%), Gaps = 28/192 (15%)
Query 462 YLSYNKYLQLTRNSFALVPSLQRLM-LRRVALKNVDSSPSP---FQPLRNLTILDLSNNN 517
YL +YL L N + +L+ L L + L N P F+ L NLT L+LSNN
Sbjct 60 YLPNVRYLALGGNKLHDISALKELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQ 119
Query 518 IANI------------------------NDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ ++ ND + EGL L L+L +NNLARLWKHANPGG
Sbjct 120 LTSLPQGVFERLASLTTLNLSNNNLANLNDKVFEGLTNLTTLNLSNNNLARLWKHANPGG 179
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
PIYFLKGL++L LNL +NGFDE P EVFKDL L ++L N L +LP VF +LK
Sbjct 180 PIYFLKGLTNLTTLNLSNNGFDEFPKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLK 239
Query 614 SLNLQKNLITSV 625
+LNL N + S+
Sbjct 240 TLNLSNNQLQSL 251
Score = 59.3 bits (142), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 62/170 (36%), Positives = 95/170 (56%), Gaps = 10/170 (6%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ LNL++NQL LP F + + LT+L++ N ++ L + ++L L LNL +N
Sbjct 84 TNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNN 143
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKI--KNNP-----FVKQ-KNLITLDLSHNGLSST 162
L+ L+DK F TNLT L+L +N++ ++ NP F+K NL TL+LS+NG
Sbjct 144 LANLNDKVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNNGFDEF 203
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L +L L LSNN++ +L + N LK L LS+NQ++
Sbjct 204 PKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTN--LKTLNLSNNQLQSL 251
Score = 55.8 bits (133), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 53/146 (36%), Positives = 81/146 (55%), Gaps = 8/146 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T LNL++NQL LP F R + LT+L++ N ++ L ++ + L L LNL +N
Sbjct 108 TNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNNLANLNDKVFEGLTNLTTLNLSNNN 167
Query 111 LSQLSDKT--------FAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSST 162
L++L TNLT L+L +N + F +L TL+LS+N L+S
Sbjct 168 LARLWKHANPGGPIYFLKGLTNLTTLNLSNNGFDEFPKEVFKDLTSLTTLNLSNNQLTSL 227
Query 163 KLGTQVQLENLQELLLSNNKIQALKS 188
G +L NL+ L LSNN++Q+L +
Sbjct 228 PQGVFERLTNLKTLNLSNNQLQSLPT 253
Score = 38.1 bits (87), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 51/171 (30%), Positives = 71/171 (42%), Gaps = 36/171 (21%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK-------- 147
++L L LNL +N+L L F TNLT L+L +N + + F +
Sbjct 81 KELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLS 140
Query 148 ----------------NLITLDLSHNGLSS----TKLGTQV----QLENLQELLLSNNKI 183
NL TL+LS+N L+ G + L NL L LSNN
Sbjct 141 NNNLANLNDKVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNNGF 200
Query 184 QALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
E +F + +SL L LS+NQ+ G F + L L L+N QL
Sbjct 201 DEFPKE---VFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLKTLNLSNNQL 248
Score = 37.4 bits (85), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 50/172 (29%), Positives = 69/172 (40%), Gaps = 49/172 (28%)
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVV----------------------- 289
L+LSN+QL T F K TNLT L+LS N L +
Sbjct 89 LNLSNNQLETLPQGVFE--KLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNNLAN 146
Query 290 -GNDSFAWLPQLEYFFLEYNNIQHLFSHS--------LHGLFNVRYLNLKRSFTKQSISL 340
+ F L L L NN+ L+ H+ L GL N+ LNL +
Sbjct 147 LNDKVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNN-------- 198
Query 341 ASLPKIDDFS---FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
D+F F+ L L LN+ +N + + +F L NLK L+LSN+
Sbjct 199 ----GFDEFPKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLKTLNLSNN 246
>4r6j_A A Lucine rich repeats DLRR_H
Length=254
Score = 124 bits (312), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 83/192 (43%), Positives = 106/192 (55%), Gaps = 28/192 (15%)
Query 462 YLSYNKYLQLTRNSFALVPSLQRLM-LRRVALKNVDSSPSP---FQPLRNLTILDLSNNN 517
YL +YL L N + +L+ L L + L N P F+ L NLT L+LSNN
Sbjct 60 YLPNVRYLALGGNKLHDISALKELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQ 119
Query 518 IANI------------------------NDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ ++ ND + EGL L L+L +NNLARLWKHANPGG
Sbjct 120 LTSLPQGVFERLASLTTLNLSNNNLANLNDKVFEGLTNLTTLNLSNNNLARLWKHANPGG 179
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
PIYFLKGL++L LNL +NGFDE P EVFKDL L ++L N L +LP VF +LK
Sbjct 180 PIYFLKGLTNLTTLNLSNNGFDEFPKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLK 239
Query 614 SLNLQKNLITSV 625
+LNL N + S+
Sbjct 240 TLNLSNNQLQSL 251
Score = 59.3 bits (142), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 62/170 (36%), Positives = 95/170 (56%), Gaps = 10/170 (6%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ LNL++NQL LP F + + LT+L++ N ++ L + ++L L LNL +N
Sbjct 84 TNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNN 143
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKI--KNNP-----FVKQ-KNLITLDLSHNGLSST 162
L+ L+DK F TNLT L+L +N++ ++ NP F+K NL TL+LS+NG
Sbjct 144 LANLNDKVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNNGFDEF 203
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L +L L LSNN++ +L + N LK L LS+NQ++
Sbjct 204 PKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTN--LKTLNLSNNQLQSL 251
Score = 55.8 bits (133), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 53/146 (36%), Positives = 81/146 (55%), Gaps = 8/146 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T LNL++NQL LP F R + LT+L++ N ++ L ++ + L L LNL +N
Sbjct 108 TNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNNLANLNDKVFEGLTNLTTLNLSNNN 167
Query 111 LSQLSDKT--------FAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSST 162
L++L TNLT L+L +N + F +L TL+LS+N L+S
Sbjct 168 LARLWKHANPGGPIYFLKGLTNLTTLNLSNNGFDEFPKEVFKDLTSLTTLNLSNNQLTSL 227
Query 163 KLGTQVQLENLQELLLSNNKIQALKS 188
G +L NL+ L LSNN++Q+L +
Sbjct 228 PQGVFERLTNLKTLNLSNNQLQSLPT 253
Score = 38.1 bits (87), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 51/171 (30%), Positives = 71/171 (42%), Gaps = 36/171 (21%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK-------- 147
++L L LNL +N+L L F TNLT L+L +N + + F +
Sbjct 81 KELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLS 140
Query 148 ----------------NLITLDLSHNGLSS----TKLGTQV----QLENLQELLLSNNKI 183
NL TL+LS+N L+ G + L NL L LSNN
Sbjct 141 NNNLANLNDKVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNNGF 200
Query 184 QALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
E +F + +SL L LS+NQ+ G F + L L L+N QL
Sbjct 201 DEFPKE---VFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLKTLNLSNNQL 248
Score = 37.4 bits (85), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 50/172 (29%), Positives = 69/172 (40%), Gaps = 49/172 (28%)
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVV----------------------- 289
L+LSN+QL T F K TNLT L+LS N L +
Sbjct 89 LNLSNNQLETLPQGVFE--KLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNNLAN 146
Query 290 -GNDSFAWLPQLEYFFLEYNNIQHLFSHS--------LHGLFNVRYLNLKRSFTKQSISL 340
+ F L L L NN+ L+ H+ L GL N+ LNL +
Sbjct 147 LNDKVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNN-------- 198
Query 341 ASLPKIDDFS---FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
D+F F+ L L LN+ +N + + +F L NLK L+LSN+
Sbjct 199 ----GFDEFPKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLKTLNLSNN 246
>4r6j_D D Lucine rich repeats DLRR_H
Length=254
Score = 124 bits (312), Expect = 2e-30, Method: Compositional matrix adjust.
Identities = 83/192 (43%), Positives = 106/192 (55%), Gaps = 28/192 (15%)
Query 462 YLSYNKYLQLTRNSFALVPSLQRLM-LRRVALKNVDSSPSP---FQPLRNLTILDLSNNN 517
YL +YL L N + +L+ L L + L N P F+ L NLT L+LSNN
Sbjct 60 YLPNVRYLALGGNKLHDISALKELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQ 119
Query 518 IANI------------------------NDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ ++ ND + EGL L L+L +NNLARLWKHANPGG
Sbjct 120 LTSLPQGVFERLASLTTLNLSNNNLANLNDKVFEGLTNLTTLNLSNNNLARLWKHANPGG 179
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
PIYFLKGL++L LNL +NGFDE P EVFKDL L ++L N L +LP VF +LK
Sbjct 180 PIYFLKGLTNLTTLNLSNNGFDEFPKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLK 239
Query 614 SLNLQKNLITSV 625
+LNL N + S+
Sbjct 240 TLNLSNNQLQSL 251
Score = 59.3 bits (142), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/170 (36%), Positives = 95/170 (56%), Gaps = 10/170 (6%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ LNL++NQL LP F + + LT+L++ N ++ L + ++L L LNL +N
Sbjct 84 TNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNN 143
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKI--KNNP-----FVKQ-KNLITLDLSHNGLSST 162
L+ L+DK F TNLT L+L +N++ ++ NP F+K NL TL+LS+NG
Sbjct 144 LANLNDKVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNNGFDEF 203
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L +L L LSNN++ +L + N LK L LS+NQ++
Sbjct 204 PKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTN--LKTLNLSNNQLQSL 251
Score = 38.1 bits (87), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 51/171 (30%), Positives = 71/171 (42%), Gaps = 36/171 (21%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK-------- 147
++L L LNL +N+L L F TNLT L+L +N + + F +
Sbjct 81 KELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLS 140
Query 148 ----------------NLITLDLSHNGLSS----TKLGTQV----QLENLQELLLSNNKI 183
NL TL+LS+N L+ G + L NL L LSNN
Sbjct 141 NNNLANLNDKVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNNGF 200
Query 184 QALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
E +F + +SL L LS+NQ+ G F + L L L+N QL
Sbjct 201 DEFPKE---VFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLKTLNLSNNQL 248
Score = 37.4 bits (85), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 50/172 (29%), Positives = 69/172 (40%), Gaps = 49/172 (28%)
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVV----------------------- 289
L+LSN+QL T F K TNLT L+LS N L +
Sbjct 89 LNLSNNQLETLPQGVFE--KLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNNLAN 146
Query 290 -GNDSFAWLPQLEYFFLEYNNIQHLFSHS--------LHGLFNVRYLNLKRSFTKQSISL 340
+ F L L L NN+ L+ H+ L GL N+ LNL +
Sbjct 147 LNDKVFEGLTNLTTLNLSNNNLARLWKHANPGGPIYFLKGLTNLTTLNLSNN-------- 198
Query 341 ASLPKIDDFS---FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
D+F F+ L L LN+ +N + + +F L NLK L+LSN+
Sbjct 199 ----GFDEFPKEVFKDLTSLTTLNLSNNQLTSLPQGVFERLTNLKTLNLSNN 246
>8ar1_A A Toll-like receptor 3
Length=50
Score = 102 bits (254), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 49/49 (100%), Positives = 49/49 (100%), Gaps = 0/49 (0%)
Query 698 DSAPFELFFMINTSILLIFIFIVLLIHFEGWRISFYWNVSVHRVLGFKE 746
DSAPFELFFMINTSILLIFIFIVLLIHFEGWRISFYWNVSVHRVLGFKE
Sbjct 2 DSAPFELFFMINTSILLIFIFIVLLIHFEGWRISFYWNVSVHRVLGFKE 50
>4z0c_B D Toll-like receptor 13
Length=709
Score = 115 bits (287), Expect = 6e-25, Method: Compositional matrix adjust.
Identities = 189/700 (27%), Positives = 305/700 (44%), Gaps = 91/700 (13%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPML 101
LT+ D+P T LNLTHN+++ LP +FT S L L + +N+I K++ + L L
Sbjct 26 LTEAISDIPRYTTHLNLTHNEIQVLPPWSFTNLSALVDLRLEWNSIWKIDEGAFRGLENL 85
Query 102 KVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS- 160
+LNL N++ +++ +F ++L L L N I I + F L L LS N +S
Sbjct 86 TLLNLVENKIQSVNN-SFEGLSSLKTLLLSHNQITHIHKDAFTPLIKLKYLSLSRNNISD 144
Query 161 -STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
S L L L+ L L+NN I L + SL L N+++E + F A
Sbjct 145 FSGILEAVQHLPCLERLDLTNNSIMYLDHSPRSLV---SLTHLSFEGNKLRELN---FSA 198
Query 220 IGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
+ L+ + G + + + L+ L NLS + +L S L+ +L+
Sbjct 199 LSLPNLTNLSASRNGNKVIQNVYLKTLPQLKSLNLSGTVIKLENLSAKHLQNLRAMDLSN 258
Query 279 LDLSYNNLNV------VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS 332
+L + +L++ +GN LP+LE + N L + +L+L ++
Sbjct 259 WELRHGHLDMKTVCHLLGN-----LPKLETLVFQKNVTNAEGIKQLAKCTRLLFLDLGQN 313
Query 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
+ L ++D F L L+ LN+ + I + ++ L NL L LS++
Sbjct 314 --------SDLIYLNDSEFNALPSLQKLNLNKCQLSFINNRTWSSLQNLTSLDLSHN--K 363
Query 393 LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
++ + F L H L L+L++N I+++ + AFS L L+ L+L I + +
Sbjct 364 FKSFPDFAFSPLKH--LEFLSLSRNPITELNNLAFSGLFALKELNLAACWI-VTIDRYSF 420
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
N+ + L N L +F + LQ L+L LK ++ P+ F L NL LD
Sbjct 421 TQFPNLEVLDLGDNNIRTLNHGTFRPLKKLQSLILSHNCLKILE--PNSFSGLTNLRSLD 478
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESN 572
L N+++ ++ + GLEKL IL L N + P LK L L+ L + +
Sbjct 479 LMYNSLSYFHEHLFSGLEKLLILKLGFNKITYETTRTLQYPPFIKLKSLKQLN-LEGQRH 537
Query 573 GFDEIPVEVFKDLFELKIIDLGLN--------------NLNTLP--------------AS 604
G +P F+ L L+ + LG N NL L AS
Sbjct 538 GIQVVPSNFFQGLGSLQELLLGKNPSVFLDHHQFDPLINLTKLDISGTKDGDRSLYLNAS 597
Query 605 VFNNQVSLKSLNLQKN--------LITSVEK-KVFGPAFRNLTEL--------------D 641
+F N LK L L+ N + +S++ +VF F NL + D
Sbjct 598 LFQNLKRLKILRLENNNLESLVPDMFSSLQSLQVFSLRFNNLKVINQSHLKNLKSLMFFD 657
Query 642 MRFNPFDCTCESIAWFVNW-INETHTNIPELSSHYLCNTP 680
+ N CTC+++ WF NW +N +IP L S Y C P
Sbjct 658 VYGNKLQCTCDNL-WFKNWSMNTEEVHIPFLRS-YPCQQP 695
>4z0c_A A Toll-like receptor 13
Length=709
Score = 115 bits (287), Expect = 6e-25, Method: Compositional matrix adjust.
Identities = 189/700 (27%), Positives = 305/700 (44%), Gaps = 91/700 (13%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPML 101
LT+ D+P T LNLTHN+++ LP +FT S L L + +N+I K++ + L L
Sbjct 26 LTEAISDIPRYTTHLNLTHNEIQVLPPWSFTNLSALVDLRLEWNSIWKIDEGAFRGLENL 85
Query 102 KVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS- 160
+LNL N++ +++ +F ++L L L N I I + F L L LS N +S
Sbjct 86 TLLNLVENKIQSVNN-SFEGLSSLKTLLLSHNQITHIHKDAFTPLIKLKYLSLSRNNISD 144
Query 161 -STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
S L L L+ L L+NN I L + SL L N+++E + F A
Sbjct 145 FSGILEAVQHLPCLERLDLTNNSIMYLDHSPRSLV---SLTHLSFEGNKLRELN---FSA 198
Query 220 IGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
+ L+ + G + + + L+ L NLS + +L S L+ +L+
Sbjct 199 LSLPNLTNLSASRNGNKVIQNVYLKTLPQLKSLNLSGTVIKLENLSAKHLQNLRAMDLSN 258
Query 279 LDLSYNNLNV------VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS 332
+L + +L++ +GN LP+LE + N L + +L+L ++
Sbjct 259 WELRHGHLDMKTVCHLLGN-----LPKLETLVFQKNVTNAEGIKQLAKCTRLLFLDLGQN 313
Query 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
+ L ++D F L L+ LN+ + I + ++ L NL L LS++
Sbjct 314 --------SDLIYLNDSEFNALPSLQKLNLNKCQLSFINNRTWSSLQNLTSLDLSHN--K 363
Query 393 LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
++ + F L H L L+L++N I+++ + AFS L L+ L+L I + +
Sbjct 364 FKSFPDFAFSPLKH--LEFLSLSRNPITELNNLAFSGLFALKELNLAACWI-VTIDRYSF 420
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
N+ + L N L +F + LQ L+L LK ++ P+ F L NL LD
Sbjct 421 TQFPNLEVLDLGDNNIRTLNHGTFRPLKKLQSLILSHNCLKILE--PNSFSGLTNLRSLD 478
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESN 572
L N+++ ++ + GLEKL IL L N + P LK L L+ L + +
Sbjct 479 LMYNSLSYFHEHLFSGLEKLLILKLGFNKITYETTRTLQYPPFIKLKSLKQLN-LEGQRH 537
Query 573 GFDEIPVEVFKDLFELKIIDLGLN--------------NLNTLP--------------AS 604
G +P F+ L L+ + LG N NL L AS
Sbjct 538 GIQVVPSNFFQGLGSLQELLLGKNPSVFLDHHQFDPLINLTKLDISGTKDGDRSLYLNAS 597
Query 605 VFNNQVSLKSLNLQKN--------LITSVEK-KVFGPAFRNLTEL--------------D 641
+F N LK L L+ N + +S++ +VF F NL + D
Sbjct 598 LFQNLKRLKILRLENNNLESLVPDMFSSLQSLQVFSLRFNNLKVINQSHLKNLKSLMFFD 657
Query 642 MRFNPFDCTCESIAWFVNW-INETHTNIPELSSHYLCNTP 680
+ N CTC+++ WF NW +N +IP L S Y C P
Sbjct 658 VYGNKLQCTCDNL-WFKNWSMNTEEVHIPFLRS-YPCQQP 695
>5zln_B B Toll-like receptor 9
Length=793
Score = 112 bits (281), Expect = 4e-24, Method: Compositional matrix adjust.
Identities = 194/795 (24%), Positives = 314/795 (39%), Gaps = 154/795 (19%)
Query 32 HEVADCSHLKLTQVPD----DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
H + DC+ L L VP +NIT L+L N++ L ++F S L L++ +N
Sbjct 15 HGLVDCNWLFLKSVPRFSAAASCSNITRLSLISNRIHHLHNSDFVHLSNLRQLNLKWNCP 74
Query 88 SK------------LEPELCQKLPMLKVLNLQHNELSQ--------------------LS 115
+EP + L+ LNL +N ++ L
Sbjct 75 PTGLSPLHFSCHMTIEPRTFLAMRTLEELNLSYNGITTVPRLPSSLVNLSLSHTNILVLD 134
Query 116 DKTFAFCTNLTELHLMSNSIQK------IKNNP--FVKQKNLITLDLSHNGLSSTKLGTQ 167
+ A +L L + N K +K P + NL L L +N L TK+ Q
Sbjct 135 ANSLAGLYSLRVLFMDGNCYYKNPCTGAVKVTPGALLGLSNLTHLSLKYNNL--TKVPRQ 192
Query 168 VQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGL 226
+ +L+ LL+S N I L E+L AN +SL+ L++ N + C HA
Sbjct 193 LP-PSLEYLLVSYNLIVKLGPEDL---ANLTSLRVLDVGGNCRR-----CDHAPNPCIEC 243
Query 227 FLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL 286
++ L P L + + L L +S L T +++ F GL N+++LDLS N L
Sbjct 244 GQKSLHLHPETFHHL------SHLEGLVLKDSSLHTLNSSWFQGL--VNMSVLDLSENFL 295
Query 287 --NVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH------GLFNVRYLNLK----RSFT 334
++ ++F L +L L +N + + LH L +++ LN+ RS
Sbjct 296 YESIQHTNAFQNLTRLRKLNLSFNYRKKVSFARLHLASSFKNLVSLQELNMNGIFFRSLN 355
Query 335 KQSIS-LASLPKIDDFSFQW-------------LKCLEHLNMEDNDIPGIKS------NM 374
K ++ LA LPK+ Q + L +++ DN I G +
Sbjct 356 KYTLRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRISGPSTLSXXXXXX 415
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
+ F+ + ++L++N + I+ + F L L+
Sbjct 416 XXXXXXXXXXXXXXXXXXXXXXXXKNFMDRCKNFKFTMDLSRNNLVTIKPEMFVQLSRLQ 475
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML----RRV 490
L L N I Q + G ++ L N+ + LS+NK SF+ +P LQ L L +
Sbjct 476 CLSLSHNSIAQAVQGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSQPF 535
Query 491 ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHAN 550
++K + + S L L L L++N+I L + LD N + R+W
Sbjct 536 SMKGIGHNFSFVAHLSMLHSLSLAHNDIHTRVSSHLNS-NSVRFLDFSGNGMGRMWDEG- 593
Query 551 PGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKD-------------------------L 585
G ++F +GLS L L+L N + + + L
Sbjct 594 -GLYLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLKLLSLRDNYLSFFQWTSLSFL 652
Query 586 FELKIIDLGLNNL-----NTLP-------------------ASVFNNQVSLKSLNLQKNL 621
L+++DL N L TLP + F V LK +NL N+
Sbjct 653 PNLEVLDLAGNQLKALTNGTLPNGTLLQKLDVSSNSIVSVVPAFFALAVELKEVNLSHNI 712
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPP 681
+ +V++ FGP NLT LD+R NP C C A FV+ + E T +P L++ C +P
Sbjct 713 LKTVDRSWFGPIVMNLTVLDVRSNPLHCACG--AAFVDLLLEVQTKVPGLANGVKCGSPG 770
Query 682 HYHGFPVRLFDTSSC 696
G + D C
Sbjct 771 QLQGRSIFAQDLRLC 785
>5zln_A A Toll-like receptor 9
Length=793
Score = 112 bits (280), Expect = 5e-24, Method: Compositional matrix adjust.
Identities = 194/795 (24%), Positives = 314/795 (39%), Gaps = 154/795 (19%)
Query 32 HEVADCSHLKLTQVPD----DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
H + DC+ L L VP +NIT L+L N++ L ++F S L L++ +N
Sbjct 15 HGLVDCNWLFLKSVPRFSAAASCSNITRLSLISNRIHHLHNSDFVHLSNLRQLNLKWNCP 74
Query 88 SK------------LEPELCQKLPMLKVLNLQHNELSQ--------------------LS 115
+EP + L+ LNL +N ++ L
Sbjct 75 PTGLSPLHFSCHMTIEPRTFLAMRTLEELNLSYNGITTVPRLPSSLVNLSLSHTNILVLD 134
Query 116 DKTFAFCTNLTELHLMSNSIQK------IKNNP--FVKQKNLITLDLSHNGLSSTKLGTQ 167
+ A +L L + N K +K P + NL L L +N L TK+ Q
Sbjct 135 ANSLAGLYSLRVLFMDGNCYYKNPCTGAVKVTPGALLGLSNLTHLSLKYNNL--TKVPRQ 192
Query 168 VQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGL 226
+ +L+ LL+S N I L E+L AN +SL+ L++ N + C HA
Sbjct 193 LP-PSLEYLLVSYNLIVKLGPEDL---ANLTSLRVLDVGGNCRR-----CDHAPNPCIEC 243
Query 227 FLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL 286
++ L P L + + L L +S L T +++ F GL N+++LDLS N L
Sbjct 244 GQKSLHLHPETFHHL------SHLEGLVLKDSSLHTLNSSWFQGL--VNMSVLDLSENFL 295
Query 287 --NVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH------GLFNVRYLNLK----RSFT 334
++ ++F L +L L +N + + LH L +++ LN+ RS
Sbjct 296 YESIQHTNAFQNLTRLRKLNLSFNYRKKVSFARLHLASSFKNLVSLQELNMNGIFFRSLN 355
Query 335 KQSIS-LASLPKIDDFSFQW-------------LKCLEHLNMEDNDIPGIKSNMFTGLIN 380
K ++ LA LPK+ Q + L +++ DN I G +
Sbjct 356 KYTLRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRISGPSTXXXXXXXX 415
Query 381 LKYLSLSNSFTSLRTLTN------ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
+ F+ + ++L++N + I+ + F L L+
Sbjct 416 XXXXXXXXXXXXXXXXXXXXXXXXKNFMDRCKNFKFTMDLSRNNLVTIKPEMFVQLSRLQ 475
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML----RRV 490
L L N I Q + G ++ L N+ + LS+NK SF+ +P LQ L L +
Sbjct 476 CLSLSHNSIAQAVQGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSQPF 535
Query 491 ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHAN 550
++K + + S L L L L++N+I L + LD N + R+W
Sbjct 536 SMKGIGHNFSFVAHLSMLHSLSLAHNDIHTRVSSHLNS-NSVRFLDFSGNGMGRMWDEG- 593
Query 551 PGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKD-------------------------L 585
G ++F +GLS L L+L N + + + L
Sbjct 594 -GLYLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLKLLSLRDNYLSFFQWTSLSFL 652
Query 586 FELKIIDLGLNNL-----NTLP-------------------ASVFNNQVSLKSLNLQKNL 621
L+++DL N L TLP + F V LK +NL N+
Sbjct 653 PNLEVLDLAGNQLKALTNGTLPNGTLLQKLDVSSNSIVSVVPAFFALAVELKEVNLSHNI 712
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPP 681
+ +V++ FGP NLT LD+R NP C C A FV+ + E T +P L++ C +P
Sbjct 713 LKTVDRSWFGPIVMNLTVLDVRSNPLHCACG--AAFVDLLLEVQTKVPGLANGVKCGSPG 770
Query 682 HYHGFPVRLFDTSSC 696
G + D C
Sbjct 771 QLQGRSIFAQDLRLC 785
>3b2d_B B CD180 antigen
Length=603
Score = 111 bits (277), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 171/678 (25%), Positives = 272/678 (40%), Gaps = 97/678 (14%)
Query 31 SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL 90
+++ +C +L L+++PD LP L + N L + F+R LT LD+ I+ +
Sbjct 10 ANKTYNCENLGLSEIPDTLPNTTEFLEFSFNFLPTIHNRTFSRLMNLTFLDLTRCQINWI 69
Query 91 EPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
+ Q L L L N L +++ + +L L L+ I ++ P +NL
Sbjct 70 HEDTFQSHHQLSTLVLTGNPLIFMAETSLNGPKSLKHLFLIQTGISNLEFIPVHNLENLE 129
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+L L N +SS K NL+ L NN I + E++ + L + N +K
Sbjct 130 SLYLGSNHISSIKFPKDFPARNLKVLDFQNNAIHYISREDMRSLEQAINLSLNFNGNNVK 189
Query 211 EFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLG 270
G F + T F
Sbjct 190 GIELGAFDS----------------------------------------------TIFQS 203
Query 271 LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL--FNVRYLN 328
L + L + +N L S WL E + + + S L GL +V LN
Sbjct 204 LNFGGTPNLSVIFNGLQNSTTQSL-WLGTFEDI-----DDEDISSAMLKGLCEMSVESLN 257
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS- 387
L+ I +FQ L+ L++ + G+ S M GL LK L LS
Sbjct 258 LQEH---------RFSDISSTTFQCFTQLQELDLTATHLKGLPSGM-KGLNLLKKLVLSV 307
Query 388 NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE--SDAFSWLGHLEVLDLGLNEI-G 444
N F L ++ F SL H L+I + + K+ LG+L+ LDL N+I
Sbjct 308 NHFDQLCQISAANFPSLTH--LYI----RGNVKKLHLGVGCLEKLGNLQTLDLSHNDIEA 361
Query 445 QELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQP 504
+ + + L ++ + LS+N+ L L +F P L+ L L L ++++ SPFQ
Sbjct 362 SDCCSLQLKNLSHLQTLNLSHNEPLGLQSQAFKECPQLELLDLAFTRL-HINAPQSPFQN 420
Query 505 LRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY---FLKGL 561
L L +L+L+ + N +L GL L L+L+ N+ G I L+ +
Sbjct 421 LHFLQVLNLTYCFLDTSNQHLLAGLPVLRHLNLKGNHFQD--------GTITKTNLLQTV 472
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKS--LNLQK 619
L +L L S G I + F L ++ +DL + N+L ++ LK LNL
Sbjct 473 GSLEVLILSSCGLLSIDQQAFHSLGKMSHVDL---SHNSLTCDSIDSLSHLKGIYLNLAA 529
Query 620 NLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNT 679
N I + ++ P + +++ NP DCTC +I F+ W E + E S C
Sbjct 530 NSINIISPRLL-PILSQQSTINLSHNPLDCTCSNI-HFLTWYKENLHKL-EGSEETTCAN 586
Query 680 PPHYHGFPVRLFDTS-SC 696
PP G V+L D SC
Sbjct 587 PPSLRG--VKLSDVKLSC 602
>3b2d_A A CD180 antigen
Length=603
Score = 111 bits (277), Expect = 7e-24, Method: Compositional matrix adjust.
Identities = 171/678 (25%), Positives = 272/678 (40%), Gaps = 97/678 (14%)
Query 31 SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL 90
+++ +C +L L+++PD LP L + N L + F+R LT LD+ I+ +
Sbjct 10 ANKTYNCENLGLSEIPDTLPNTTEFLEFSFNFLPTIHNRTFSRLMNLTFLDLTRCQINWI 69
Query 91 EPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
+ Q L L L N L +++ + +L L L+ I ++ P +NL
Sbjct 70 HEDTFQSHHQLSTLVLTGNPLIFMAETSLNGPKSLKHLFLIQTGISNLEFIPVHNLENLE 129
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+L L N +SS K NL+ L NN I + E++ + L + N +K
Sbjct 130 SLYLGSNHISSIKFPKDFPARNLKVLDFQNNAIHYISREDMRSLEQAINLSLNFNGNNVK 189
Query 211 EFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLG 270
G F + T F
Sbjct 190 GIELGAFDS----------------------------------------------TIFQS 203
Query 271 LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL--FNVRYLN 328
L + L + +N L S WL E + + + S L GL +V LN
Sbjct 204 LNFGGTPNLSVIFNGLQNSTTQSL-WLGTFEDI-----DDEDISSAMLKGLCEMSVESLN 257
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS- 387
L+ I +FQ L+ L++ + G+ S M GL LK L LS
Sbjct 258 LQEH---------RFSDISSTTFQCFTQLQELDLTATHLKGLPSGM-KGLNLLKKLVLSV 307
Query 388 NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE--SDAFSWLGHLEVLDLGLNEI-G 444
N F L ++ F SL H L+I + + K+ LG+L+ LDL N+I
Sbjct 308 NHFDQLCQISAANFPSLTH--LYI----RGNVKKLHLGVGCLEKLGNLQTLDLSHNDIEA 361
Query 445 QELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQP 504
+ + + L ++ + LS+N+ L L +F P L+ L L L ++++ SPFQ
Sbjct 362 SDCCSLQLKNLSHLQTLNLSHNEPLGLQSQAFKECPQLELLDLAFTRL-HINAPQSPFQN 420
Query 505 LRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY---FLKGL 561
L L +L+L+ + N +L GL L L+L+ N+ G I L+ +
Sbjct 421 LHFLQVLNLTYCFLDTSNQHLLAGLPVLRHLNLKGNHFQD--------GTITKTNLLQTV 472
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKS--LNLQK 619
L +L L S G I + F L ++ +DL + N+L ++ LK LNL
Sbjct 473 GSLEVLILSSCGLLSIDQQAFHSLGKMSHVDL---SHNSLTCDSIDSLSHLKGIYLNLAA 529
Query 620 NLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNT 679
N I + ++ P + +++ NP DCTC +I F+ W E + E S C
Sbjct 530 NSINIISPRLL-PILSQQSTINLSHNPLDCTCSNI-HFLTWYKENLHKL-EGSEETTCAN 586
Query 680 PPHYHGFPVRLFDTS-SC 696
PP G V+L D SC
Sbjct 587 PPSLRG--VKLSDVKLSC 602
>4li1_B A Leucine-rich repeat-containing G-protein coupled receptor
4
Length=432
Score = 108 bits (269), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 126/439 (29%), Positives = 198/439 (45%), Gaps = 42/439 (10%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
ADCS L VPD L L+L+ N + +LP F + L L + N +S + P
Sbjct 21 ADCSGKGLVTVPDGLSVFTHSLDLSMNNITKLPEGAFKGFPYLEELRLAGNDLSIIHPMA 80
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + ++ +L L L +N I + + F L L L
Sbjct 81 LSGLKELKVLTLQNNQLKTVPSESLKGLVSLQSLRLDANHIVTVPEDSFEGLVQLRHLWL 140
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L +LQ L L+ NKI + F+N SSL L L +N+I+
Sbjct 141 DDNSLTEVPIRPLSNLPSLQALTLALNKISHIPDYA---FSNLSSLVVLHLHNNKIRTLG 197
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
P CFH + L L L NN+ P L +++ L ++ ++ + F +
Sbjct 198 PHCFHGLDNLEALDLNYNNLIDFPDSIRSL------PNLKELGFHSNSITIIPDGAF--V 249
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL-NLK 330
K L + L N L+ VGN +F L L + + G NV++ NL
Sbjct 250 KNPLLRTIHLYDNPLSFVGNSAFQNLSDLHFLIIR-------------GASNVQWFPNLT 296
Query 331 RSFTKQSISLASLPKIDDFSFQWL---KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
+ +S++L KI ++ K L L++ N+I + F G +L+ + L
Sbjct 297 GTNNLESLTLTGT-KIRSIPIKFCQEQKMLRTLDLSYNEISALVG--FEGCSSLEEVYLQ 353
Query 388 NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQEL 447
N+ ++ + NETF LA L +L+L++N+I I +AF L L LDL N +L
Sbjct 354 NN--QIQEVQNETFQGLA--ALRMLDLSRNRIHTIHKEAFVTLKALTNLDLSFN----DL 405
Query 448 TGQEWRGLENIFEIYLSYN 466
T GL + ++ L+ N
Sbjct 406 TAFPTAGLHGLNQLKLTGN 424
Score = 77.0 bits (188), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 108/413 (26%), Positives = 174/413 (42%), Gaps = 74/413 (18%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDLS NN+ + +F P LE L N++ + +L GL ++ L L+ +
Sbjct 42 LDLSMNNITKLPEGAFKGFPYLEELRLAGNDLSIIHPMALSGLKELKVLTLQNN------ 95
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
L + S + L L+ L ++ N I + + F GL+ L++L L ++ +LT
Sbjct 96 ---QLKTVPSESLKGLVSLQSLRLDANHIVTVPEDSFEGLVQLRHLWLDDN-----SLTE 147
Query 399 ETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN 457
L++ P L L L NKIS I AFS L L VL L N+I + L + GL+N
Sbjct 148 VPIRPLSNLPSLQALTLALNKISHIPDYAFSNLSSLVVLHLHNNKI-RTLGPHCFHGLDN 206
Query 458 IFEIYLSYN---------------KYLQLTRNSFALVPS---LQRLMLRRVALKNVDSS- 498
+ + L+YN K L NS ++P ++ +LR + L + S
Sbjct 207 LEALDLNYNNLIDFPDSIRSLPNLKELGFHSNSITIIPDGAFVKNPLLRTIHLYDNPLSF 266
Query 499 --PSPFQPL-----------------------RNLTILDLSNNNIANINDDMLEGLEKLE 533
S FQ L NL L L+ I +I + + L
Sbjct 267 VGNSAFQNLSDLHFLIIRGASNVQWFPNLTGTNNLESLTLTGTKIRSIPIKFCQEQKMLR 326
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LDL +N ++ L +G S L + L++N E+ E F+ L L+++DL
Sbjct 327 TLDLSYNEISALVG----------FEGCSSLEEVYLQNNQIQEVQNETFQGLAALRMLDL 376
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNP 646
N ++T+ F +L +L+L N +T+ L +L + NP
Sbjct 377 SRNRIHTIHKEAFVTLKALTNLDLSFNDLTAFPTA----GLHGLNQLKLTGNP 425
>4li1_A B Leucine-rich repeat-containing G-protein coupled receptor
4
Length=432
Score = 108 bits (269), Expect = 2e-23, Method: Compositional matrix adjust.
Identities = 126/439 (29%), Positives = 198/439 (45%), Gaps = 42/439 (10%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
ADCS L VPD L L+L+ N + +LP F + L L + N +S + P
Sbjct 21 ADCSGKGLVTVPDGLSVFTHSLDLSMNNITKLPEGAFKGFPYLEELRLAGNDLSIIHPMA 80
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + ++ +L L L +N I + + F L L L
Sbjct 81 LSGLKELKVLTLQNNQLKTVPSESLKGLVSLQSLRLDANHIVTVPEDSFEGLVQLRHLWL 140
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L +LQ L L+ NKI + F+N SSL L L +N+I+
Sbjct 141 DDNSLTEVPIRPLSNLPSLQALTLALNKISHIPDYA---FSNLSSLVVLHLHNNKIRTLG 197
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
P CFH + L L L NN+ P L +++ L ++ ++ + F +
Sbjct 198 PHCFHGLDNLEALDLNYNNLIDFPDSIRSL------PNLKELGFHSNSITIIPDGAF--V 249
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL-NLK 330
K L + L N L+ VGN +F L L + + G NV++ NL
Sbjct 250 KNPLLRTIHLYDNPLSFVGNSAFQNLSDLHFLIIR-------------GASNVQWFPNLT 296
Query 331 RSFTKQSISLASLPKIDDFSFQWL---KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
+ +S++L KI ++ K L L++ N+I + F G +L+ + L
Sbjct 297 GTNNLESLTLTGT-KIRSIPIKFCQEQKMLRTLDLSYNEISALVG--FEGCSSLEEVYLQ 353
Query 388 NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQEL 447
N+ ++ + NETF LA L +L+L++N+I I +AF L L LDL N +L
Sbjct 354 NN--QIQEVQNETFQGLA--ALRMLDLSRNRIHTIHKEAFVTLKALTNLDLSFN----DL 405
Query 448 TGQEWRGLENIFEIYLSYN 466
T GL + ++ L+ N
Sbjct 406 TAFPTAGLHGLNQLKLTGN 424
Score = 77.0 bits (188), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 108/413 (26%), Positives = 174/413 (42%), Gaps = 74/413 (18%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDLS NN+ + +F P LE L N++ + +L GL ++ L L+ +
Sbjct 42 LDLSMNNITKLPEGAFKGFPYLEELRLAGNDLSIIHPMALSGLKELKVLTLQNN------ 95
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
L + S + L L+ L ++ N I + + F GL+ L++L L ++ +LT
Sbjct 96 ---QLKTVPSESLKGLVSLQSLRLDANHIVTVPEDSFEGLVQLRHLWLDDN-----SLTE 147
Query 399 ETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN 457
L++ P L L L NKIS I AFS L L VL L N+I + L + GL+N
Sbjct 148 VPIRPLSNLPSLQALTLALNKISHIPDYAFSNLSSLVVLHLHNNKI-RTLGPHCFHGLDN 206
Query 458 IFEIYLSYN---------------KYLQLTRNSFALVPS---LQRLMLRRVALKNVDSS- 498
+ + L+YN K L NS ++P ++ +LR + L + S
Sbjct 207 LEALDLNYNNLIDFPDSIRSLPNLKELGFHSNSITIIPDGAFVKNPLLRTIHLYDNPLSF 266
Query 499 --PSPFQPL-----------------------RNLTILDLSNNNIANINDDMLEGLEKLE 533
S FQ L NL L L+ I +I + + L
Sbjct 267 VGNSAFQNLSDLHFLIIRGASNVQWFPNLTGTNNLESLTLTGTKIRSIPIKFCQEQKMLR 326
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LDL +N ++ L +G S L + L++N E+ E F+ L L+++DL
Sbjct 327 TLDLSYNEISALVG----------FEGCSSLEEVYLQNNQIQEVQNETFQGLAALRMLDL 376
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNP 646
N ++T+ F +L +L+L N +T+ L +L + NP
Sbjct 377 SRNRIHTIHKEAFVTLKALTNLDLSFNDLTAFPTA----GLHGLNQLKLTGNP 425
>5a5c_B B LRRTM
Length=357
Score = 103 bits (258), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 100/287 (35%), Positives = 136/287 (47%), Gaps = 31/287 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC + C VP+ LP+ + L+L HNQL+ LP F + +QLT
Sbjct 8 KCRCEKLLFYCDSQGFHSVPNGLPSQLLGLSLRHNQLQSLPNGVFDKLTQLT-------- 59
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
L+L HN+L L + F T LTEL L SN +Q + N F K
Sbjct 60 ----------------WLHLDHNQLQSLPNGVFDKLTKLTELILSSNQLQSLPNGTFDKL 103
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
NL LDLS N L S G +L NLQ L L +N++Q+L + D +SL L+LS+
Sbjct 104 TNLQNLDLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNGVFDKL--TSLTFLDLST 161
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
NQ++ G F + L L L + QL SL + +L TS+ L L +QL + N
Sbjct 162 NQLQSLPNGVFDKLTNLRELHLEHNQL-QSLPNGVFDKL--TSLTTLFLQWNQLQSLPNG 218
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
F K TNL LDL+ N L + N F L L+ L+ N +Q L
Sbjct 219 VF--DKLTNLEKLDLTGNQLQSLPNGVFDKLTNLKILLLDNNQLQSL 263
Score = 93.2 bits (230), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 92/249 (37%), Positives = 127/249 (51%), Gaps = 10/249 (4%)
Query 39 HLKLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
H +L +P+ D T +T L+L HNQL+ LP F + ++LT L + N + L
Sbjct 41 HNQLQSLPNGVFDKLTQLTWLHLDHNQLQSLPNGVFDKLTKLTELILSSNQLQSLPNGTF 100
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
KL L+ L+L N+L L + F TNL LHL SN +Q + N F K +L LDLS
Sbjct 101 DKLTNLQNLDLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNGVFDKLTSLTFLDLS 160
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L S G +L NL+EL L +N++Q+L + D +SL L L NQ++ G
Sbjct 161 TNQLQSLPNGVFDKLTNLRELHLEHNQLQSLPNGVFDKL--TSLTTLFLQWNQLQSLPNG 218
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTN 275
F + L L L QL SL + +L N I L L N+QL + N F LK +
Sbjct 219 VFDKLTNLEKLDLTGNQL-QSLPNGVFDKLTNLKI--LLLDNNQLQSLPNGVFDKLK--S 273
Query 276 LTMLDLSYN 284
LT + LS N
Sbjct 274 LTTVGLSGN 282
Score = 82.0 bits (201), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 69/182 (38%), Positives = 97/182 (53%), Gaps = 6/182 (3%)
Query 36 DCSHLKLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D S +L +P+ D TN+ L+L NQL+ LP F + + LT LD+ N + L
Sbjct 110 DLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNGVFDKLTSLTFLDLSTNQLQSLPN 169
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITL 152
+ KL L+ L+L+HN+L L + F T+LT L L N +Q + N F K NL L
Sbjct 170 GVFDKLTNLRELHLEHNQLQSLPNGVFDKLTSLTTLFLQWNQLQSLPNGVFDKLTNLEKL 229
Query 153 DLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
DL+ N L S G +L NL+ LLL NN++Q+L + D SL + LS N + E
Sbjct 230 DLTGNQLQSLPNGVFDKLTNLKILLLDNNQLQSLPNGVFDKLK--SLTTVGLSGN-LWEC 286
Query 213 SP 214
SP
Sbjct 287 SP 288
Score = 66.2 bits (160), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 78/300 (26%), Positives = 125/300 (42%), Gaps = 44/300 (15%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L N++ + + F L L L L N++ Q L + L + E+ LS N+ L
Sbjct 37 LSLRHNQLQSLPNGVFDKLTQLTWLHLDHNQL-QSLPNGVFDKLTKLTELILSSNQLQSL 95
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
+F + +LQ L L L+++ + F L NL L L +N + ++ + + + L
Sbjct 96 PNGTFDKLTNLQNLDLSFNQLQSLPNGV--FDKLTNLQTLHLRSNQLQSLPNGVFDKLTS 153
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L LDL N L L P G L L LH LE N +P VF L L +
Sbjct 154 LTFLDLSTNQLQSL-----PNGVFDKLTNLRELH---LEHNQLQSLPNGVFDKLTSLTTL 205
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP------------------- 632
L N L +LP VF+ +L+ L+L N + S+ VF
Sbjct 206 FLQWNQLQSLPNGVFDKLTNLEKLDLTGNQLQSLPNGVFDKLTNLKILLLDNNQLQSLPN 265
Query 633 ----AFRNLTELDMRFNPFDCT---CESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
++LT + + N ++C+ C +W ++ +I LC++P H G
Sbjct 266 GVFDKLKSLTTVGLSGNLWECSPRVCALASWLGSFQGRWEHSI-------LCHSPDHTQG 318
Score = 65.9 bits (159), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 83/272 (31%), Positives = 133/272 (49%), Gaps = 19/272 (7%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
S L L L NQ++ G F + +L L L++ QL SL + +L T + L LS
Sbjct 32 SQLLGLSLRHNQLQSLPNGVFDKLTQLTWLHLDHNQL-QSLPNGVFDKL--TKLTELILS 88
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
++QL + N TF K TNL LDLS+N L + N F L L+ L N +Q L +
Sbjct 89 SNQLQSLPNGTFD--KLTNLQNLDLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNG 146
Query 317 SLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFT 376
L ++ +L+L + L SLP + F L L L++E N + + + +F
Sbjct 147 VFDKLTSLTFLDLSTN------QLQSLP---NGVFDKLTNLRELHLEHNQLQSLPNGVFD 197
Query 377 GLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVL 436
L +L L L + L++L N F L + L L+LT N++ + + F L +L++L
Sbjct 198 KLTSLTTLFL--QWNQLQSLPNGVFDKLTN--LEKLDLTGNQLQSLPNGVFDKLTNLKIL 253
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L N++ Q L + L+++ + LS N +
Sbjct 254 LLDNNQL-QSLPNGVFDKLKSLTTVGLSGNLW 284
Score = 59.3 bits (142), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 55/188 (29%), Positives = 88/188 (47%), Gaps = 11/188 (6%)
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
+ + L +N+ L F + L L L L+++ + F L LT L LS+N
Sbjct 34 LLGLSLRHNQLQSLPNGVFDKLTQLTWLHLDHNQLQSLPNGV--FDKLTKLTELILSSNQ 91
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI 577
+ ++ + + L L+ LDL N L L P L++L L+L SN +
Sbjct 92 LQSLPNGTFDKLTNLQNLDLSFNQLQSL--------PNGVFDKLTNLQTLHLRSNQLQSL 143
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNL 637
P VF L L +DL N L +LP VF+ +L+ L+L+ N + S+ VF +L
Sbjct 144 PNGVFDKLTSLTFLDLSTNQLQSLPNGVFDKLTNLRELHLEHNQLQSLPNGVFD-KLTSL 202
Query 638 TELDMRFN 645
T L +++N
Sbjct 203 TTLFLQWN 210
Score = 39.3 bits (90), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 33/98 (34%), Positives = 42/98 (43%), Gaps = 7/98 (7%)
Query 548 HANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
H+ P G L GLS L N +P VF L +L + L N L +LP VF+
Sbjct 24 HSVPNGLPSQLLGLS------LRHNQLQSLPNGVFDKLTQLTWLHLDHNQLQSLPNGVFD 77
Query 608 NQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L L L N + S+ F NL LD+ FN
Sbjct 78 KLTKLTELILSSNQLQSLPNGTFD-KLTNLQNLDLSFN 114
>5a5c_C C LRRTM
Length=357
Score = 103 bits (257), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 100/287 (35%), Positives = 136/287 (47%), Gaps = 31/287 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC + C VP+ LP+ + L+L HNQL+ LP F + +QLT
Sbjct 8 KCRCEKLLFYCDSQGFHSVPNGLPSQLLGLSLRHNQLQSLPNGVFDKLTQLT-------- 59
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
L+L HN+L L + F T LTEL L SN +Q + N F K
Sbjct 60 ----------------WLHLDHNQLQSLPNGVFDKLTKLTELILSSNQLQSLPNGTFDKL 103
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
NL LDLS N L S G +L NLQ L L +N++Q+L + D +SL L+LS+
Sbjct 104 TNLQNLDLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNGVFDKL--TSLTFLDLST 161
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
NQ++ G F + L L L + QL SL + +L TS+ L L +QL + N
Sbjct 162 NQLQSLPNGVFDKLTNLRELHLEHNQL-QSLPNGVFDKL--TSLTTLFLQWNQLQSLPNG 218
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
F K TNL LDL+ N L + N F L L+ L+ N +Q L
Sbjct 219 VF--DKLTNLEKLDLTGNQLQSLPNGVFDKLTNLKILLLDNNQLQSL 263
Score = 92.8 bits (229), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 92/249 (37%), Positives = 127/249 (51%), Gaps = 10/249 (4%)
Query 39 HLKLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
H +L +P+ D T +T L+L HNQL+ LP F + ++LT L + N + L
Sbjct 41 HNQLQSLPNGVFDKLTQLTWLHLDHNQLQSLPNGVFDKLTKLTELILSSNQLQSLPNGTF 100
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
KL L+ L+L N+L L + F TNL LHL SN +Q + N F K +L LDLS
Sbjct 101 DKLTNLQNLDLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNGVFDKLTSLTFLDLS 160
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L S G +L NL+EL L +N++Q+L + D +SL L L NQ++ G
Sbjct 161 TNQLQSLPNGVFDKLTNLRELHLEHNQLQSLPNGVFDKL--TSLTTLFLQWNQLQSLPNG 218
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTN 275
F + L L L QL SL + +L N I L L N+QL + N F LK +
Sbjct 219 VFDKLTNLEKLDLTGNQL-QSLPNGVFDKLTNLKI--LLLDNNQLQSLPNGVFDKLK--S 273
Query 276 LTMLDLSYN 284
LT + LS N
Sbjct 274 LTTVGLSGN 282
Score = 81.6 bits (200), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 69/182 (38%), Positives = 97/182 (53%), Gaps = 6/182 (3%)
Query 36 DCSHLKLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D S +L +P+ D TN+ L+L NQL+ LP F + + LT LD+ N + L
Sbjct 110 DLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNGVFDKLTSLTFLDLSTNQLQSLPN 169
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITL 152
+ KL L+ L+L+HN+L L + F T+LT L L N +Q + N F K NL L
Sbjct 170 GVFDKLTNLRELHLEHNQLQSLPNGVFDKLTSLTTLFLQWNQLQSLPNGVFDKLTNLEKL 229
Query 153 DLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
DL+ N L S G +L NL+ LLL NN++Q+L + D SL + LS N + E
Sbjct 230 DLTGNQLQSLPNGVFDKLTNLKILLLDNNQLQSLPNGVFDKLK--SLTTVGLSGN-LWEC 286
Query 213 SP 214
SP
Sbjct 287 SP 288
Score = 66.6 bits (161), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 78/300 (26%), Positives = 125/300 (42%), Gaps = 44/300 (15%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L N++ + + F L L L L N++ Q L + L + E+ LS N+ L
Sbjct 37 LSLRHNQLQSLPNGVFDKLTQLTWLHLDHNQL-QSLPNGVFDKLTKLTELILSSNQLQSL 95
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
+F + +LQ L L L+++ + F L NL L L +N + ++ + + + L
Sbjct 96 PNGTFDKLTNLQNLDLSFNQLQSLPNGV--FDKLTNLQTLHLRSNQLQSLPNGVFDKLTS 153
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L LDL N L L P G L L LH LE N +P VF L L +
Sbjct 154 LTFLDLSTNQLQSL-----PNGVFDKLTNLRELH---LEHNQLQSLPNGVFDKLTSLTTL 205
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP------------------- 632
L N L +LP VF+ +L+ L+L N + S+ VF
Sbjct 206 FLQWNQLQSLPNGVFDKLTNLEKLDLTGNQLQSLPNGVFDKLTNLKILLLDNNQLQSLPN 265
Query 633 ----AFRNLTELDMRFNPFDCT---CESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
++LT + + N ++C+ C +W ++ +I LC++P H G
Sbjct 266 GVFDKLKSLTTVGLSGNLWECSPRVCALASWLGSFQGRWEHSI-------LCHSPDHTQG 318
Score = 66.2 bits (160), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 83/272 (31%), Positives = 133/272 (49%), Gaps = 19/272 (7%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
S L L L NQ++ G F + +L L L++ QL SL + +L T + L LS
Sbjct 32 SQLLGLSLRHNQLQSLPNGVFDKLTQLTWLHLDHNQL-QSLPNGVFDKL--TKLTELILS 88
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
++QL + N TF K TNL LDLS+N L + N F L L+ L N +Q L +
Sbjct 89 SNQLQSLPNGTFD--KLTNLQNLDLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNG 146
Query 317 SLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFT 376
L ++ +L+L + L SLP + F L L L++E N + + + +F
Sbjct 147 VFDKLTSLTFLDLSTN------QLQSLP---NGVFDKLTNLRELHLEHNQLQSLPNGVFD 197
Query 377 GLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVL 436
L +L L L + L++L N F L + L L+LT N++ + + F L +L++L
Sbjct 198 KLTSLTTLFL--QWNQLQSLPNGVFDKLTN--LEKLDLTGNQLQSLPNGVFDKLTNLKIL 253
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L N++ Q L + L+++ + LS N +
Sbjct 254 LLDNNQL-QSLPNGVFDKLKSLTTVGLSGNLW 284
Score = 58.9 bits (141), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 55/188 (29%), Positives = 88/188 (47%), Gaps = 11/188 (6%)
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
+ + L +N+ L F + L L L L+++ + F L LT L LS+N
Sbjct 34 LLGLSLRHNQLQSLPNGVFDKLTQLTWLHLDHNQLQSLPNGV--FDKLTKLTELILSSNQ 91
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI 577
+ ++ + + L L+ LDL N L L P L++L L+L SN +
Sbjct 92 LQSLPNGTFDKLTNLQNLDLSFNQLQSL--------PNGVFDKLTNLQTLHLRSNQLQSL 143
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNL 637
P VF L L +DL N L +LP VF+ +L+ L+L+ N + S+ VF +L
Sbjct 144 PNGVFDKLTSLTFLDLSTNQLQSLPNGVFDKLTNLRELHLEHNQLQSLPNGVFD-KLTSL 202
Query 638 TELDMRFN 645
T L +++N
Sbjct 203 TTLFLQWN 210
Score = 39.7 bits (91), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 33/98 (34%), Positives = 42/98 (43%), Gaps = 7/98 (7%)
Query 548 HANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
H+ P G L GLS L N +P VF L +L + L N L +LP VF+
Sbjct 24 HSVPNGLPSQLLGLS------LRHNQLQSLPNGVFDKLTQLTWLHLDHNQLQSLPNGVFD 77
Query 608 NQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L L L N + S+ F NL LD+ FN
Sbjct 78 KLTKLTELILSSNQLQSLPNGTFD-KLTNLQNLDLSFN 114
>5a5c_D D LRRTM
Length=357
Score = 103 bits (257), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 100/287 (35%), Positives = 136/287 (47%), Gaps = 31/287 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC + C VP+ LP+ + L+L HNQL+ LP F + +QLT
Sbjct 8 KCRCEKLLFYCDSQGFHSVPNGLPSQLLGLSLRHNQLQSLPNGVFDKLTQLT-------- 59
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
L+L HN+L L + F T LTEL L SN +Q + N F K
Sbjct 60 ----------------WLHLDHNQLQSLPNGVFDKLTKLTELILSSNQLQSLPNGTFDKL 103
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
NL LDLS N L S G +L NLQ L L +N++Q+L + D +SL L+LS+
Sbjct 104 TNLQNLDLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNGVFDKL--TSLTFLDLST 161
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
NQ++ G F + L L L + QL SL + +L TS+ L L +QL + N
Sbjct 162 NQLQSLPNGVFDKLTNLRELHLEHNQL-QSLPNGVFDKL--TSLTTLFLQWNQLQSLPNG 218
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
F K TNL LDL+ N L + N F L L+ L+ N +Q L
Sbjct 219 VF--DKLTNLEKLDLTGNQLQSLPNGVFDKLTNLKILLLDNNQLQSL 263
Score = 92.8 bits (229), Expect = 8e-19, Method: Compositional matrix adjust.
Identities = 92/249 (37%), Positives = 127/249 (51%), Gaps = 10/249 (4%)
Query 39 HLKLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
H +L +P+ D T +T L+L HNQL+ LP F + ++LT L + N + L
Sbjct 41 HNQLQSLPNGVFDKLTQLTWLHLDHNQLQSLPNGVFDKLTKLTELILSSNQLQSLPNGTF 100
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
KL L+ L+L N+L L + F TNL LHL SN +Q + N F K +L LDLS
Sbjct 101 DKLTNLQNLDLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNGVFDKLTSLTFLDLS 160
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L S G +L NL+EL L +N++Q+L + D +SL L L NQ++ G
Sbjct 161 TNQLQSLPNGVFDKLTNLRELHLEHNQLQSLPNGVFDKL--TSLTTLFLQWNQLQSLPNG 218
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTN 275
F + L L L QL SL + +L N I L L N+QL + N F LK +
Sbjct 219 VFDKLTNLEKLDLTGNQL-QSLPNGVFDKLTNLKI--LLLDNNQLQSLPNGVFDKLK--S 273
Query 276 LTMLDLSYN 284
LT + LS N
Sbjct 274 LTTVGLSGN 282
Score = 81.6 bits (200), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 69/182 (38%), Positives = 97/182 (53%), Gaps = 6/182 (3%)
Query 36 DCSHLKLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D S +L +P+ D TN+ L+L NQL+ LP F + + LT LD+ N + L
Sbjct 110 DLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNGVFDKLTSLTFLDLSTNQLQSLPN 169
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITL 152
+ KL L+ L+L+HN+L L + F T+LT L L N +Q + N F K NL L
Sbjct 170 GVFDKLTNLRELHLEHNQLQSLPNGVFDKLTSLTTLFLQWNQLQSLPNGVFDKLTNLEKL 229
Query 153 DLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
DL+ N L S G +L NL+ LLL NN++Q+L + D SL + LS N + E
Sbjct 230 DLTGNQLQSLPNGVFDKLTNLKILLLDNNQLQSLPNGVFDKLK--SLTTVGLSGN-LWEC 286
Query 213 SP 214
SP
Sbjct 287 SP 288
Score = 66.6 bits (161), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 78/300 (26%), Positives = 125/300 (42%), Gaps = 44/300 (15%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L N++ + + F L L L L N++ Q L + L + E+ LS N+ L
Sbjct 37 LSLRHNQLQSLPNGVFDKLTQLTWLHLDHNQL-QSLPNGVFDKLTKLTELILSSNQLQSL 95
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
+F + +LQ L L L+++ + F L NL L L +N + ++ + + + L
Sbjct 96 PNGTFDKLTNLQNLDLSFNQLQSLPNGV--FDKLTNLQTLHLRSNQLQSLPNGVFDKLTS 153
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L LDL N L L P G L L LH LE N +P VF L L +
Sbjct 154 LTFLDLSTNQLQSL-----PNGVFDKLTNLRELH---LEHNQLQSLPNGVFDKLTSLTTL 205
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP------------------- 632
L N L +LP VF+ +L+ L+L N + S+ VF
Sbjct 206 FLQWNQLQSLPNGVFDKLTNLEKLDLTGNQLQSLPNGVFDKLTNLKILLLDNNQLQSLPN 265
Query 633 ----AFRNLTELDMRFNPFDCT---CESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
++LT + + N ++C+ C +W ++ +I LC++P H G
Sbjct 266 GVFDKLKSLTTVGLSGNLWECSPRVCALASWLGSFQGRWEHSI-------LCHSPDHTQG 318
Score = 66.2 bits (160), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 83/272 (31%), Positives = 133/272 (49%), Gaps = 19/272 (7%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
S L L L NQ++ G F + +L L L++ QL SL + +L T + L LS
Sbjct 32 SQLLGLSLRHNQLQSLPNGVFDKLTQLTWLHLDHNQL-QSLPNGVFDKL--TKLTELILS 88
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
++QL + N TF K TNL LDLS+N L + N F L L+ L N +Q L +
Sbjct 89 SNQLQSLPNGTFD--KLTNLQNLDLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNG 146
Query 317 SLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFT 376
L ++ +L+L + L SLP + F L L L++E N + + + +F
Sbjct 147 VFDKLTSLTFLDLSTN------QLQSLP---NGVFDKLTNLRELHLEHNQLQSLPNGVFD 197
Query 377 GLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVL 436
L +L L L + L++L N F L + L L+LT N++ + + F L +L++L
Sbjct 198 KLTSLTTLFL--QWNQLQSLPNGVFDKLTN--LEKLDLTGNQLQSLPNGVFDKLTNLKIL 253
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L N++ Q L + L+++ + LS N +
Sbjct 254 LLDNNQL-QSLPNGVFDKLKSLTTVGLSGNLW 284
Score = 58.9 bits (141), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 55/188 (29%), Positives = 88/188 (47%), Gaps = 11/188 (6%)
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
+ + L +N+ L F + L L L L+++ + F L LT L LS+N
Sbjct 34 LLGLSLRHNQLQSLPNGVFDKLTQLTWLHLDHNQLQSLPNGV--FDKLTKLTELILSSNQ 91
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI 577
+ ++ + + L L+ LDL N L L P L++L L+L SN +
Sbjct 92 LQSLPNGTFDKLTNLQNLDLSFNQLQSL--------PNGVFDKLTNLQTLHLRSNQLQSL 143
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNL 637
P VF L L +DL N L +LP VF+ +L+ L+L+ N + S+ VF +L
Sbjct 144 PNGVFDKLTSLTFLDLSTNQLQSLPNGVFDKLTNLRELHLEHNQLQSLPNGVFD-KLTSL 202
Query 638 TELDMRFN 645
T L +++N
Sbjct 203 TTLFLQWN 210
Score = 39.7 bits (91), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 33/98 (34%), Positives = 42/98 (43%), Gaps = 7/98 (7%)
Query 548 HANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
H+ P G L GLS L N +P VF L +L + L N L +LP VF+
Sbjct 24 HSVPNGLPSQLLGLS------LRHNQLQSLPNGVFDKLTQLTWLHLDHNQLQSLPNGVFD 77
Query 608 NQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L L L N + S+ F NL LD+ FN
Sbjct 78 KLTKLTELILSSNQLQSLPNGTFD-KLTNLQNLDLSFN 114
>5a5c_A A LRRTM
Length=357
Score = 103 bits (256), Expect = 3e-22, Method: Compositional matrix adjust.
Identities = 100/287 (35%), Positives = 136/287 (47%), Gaps = 31/287 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC + C VP+ LP+ + L+L HNQL+ LP F + +QLT
Sbjct 8 KCRCEKLLFYCDSQGFHSVPNGLPSQLLGLSLRHNQLQSLPNGVFDKLTQLT-------- 59
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
L+L HN+L L + F T LTEL L SN +Q + N F K
Sbjct 60 ----------------WLHLDHNQLQSLPNGVFDKLTKLTELILSSNQLQSLPNGTFDKL 103
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
NL LDLS N L S G +L NLQ L L +N++Q+L + D +SL L+LS+
Sbjct 104 TNLQNLDLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNGVFDKL--TSLTFLDLST 161
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
NQ++ G F + L L L + QL SL + +L TS+ L L +QL + N
Sbjct 162 NQLQSLPNGVFDKLTNLRELHLEHNQL-QSLPNGVFDKL--TSLTTLFLQWNQLQSLPNG 218
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
F K TNL LDL+ N L + N F L L+ L+ N +Q L
Sbjct 219 VF--DKLTNLEKLDLTGNQLQSLPNGVFDKLTNLKILLLDNNQLQSL 263
Score = 92.8 bits (229), Expect = 9e-19, Method: Compositional matrix adjust.
Identities = 92/249 (37%), Positives = 127/249 (51%), Gaps = 10/249 (4%)
Query 39 HLKLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
H +L +P+ D T +T L+L HNQL+ LP F + ++LT L + N + L
Sbjct 41 HNQLQSLPNGVFDKLTQLTWLHLDHNQLQSLPNGVFDKLTKLTELILSSNQLQSLPNGTF 100
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
KL L+ L+L N+L L + F TNL LHL SN +Q + N F K +L LDLS
Sbjct 101 DKLTNLQNLDLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNGVFDKLTSLTFLDLS 160
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L S G +L NL+EL L +N++Q+L + D +SL L L NQ++ G
Sbjct 161 TNQLQSLPNGVFDKLTNLRELHLEHNQLQSLPNGVFDKL--TSLTTLFLQWNQLQSLPNG 218
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTN 275
F + L L L QL SL + +L N I L L N+QL + N F LK +
Sbjct 219 VFDKLTNLEKLDLTGNQL-QSLPNGVFDKLTNLKI--LLLDNNQLQSLPNGVFDKLK--S 273
Query 276 LTMLDLSYN 284
LT + LS N
Sbjct 274 LTTVGLSGN 282
Score = 81.6 bits (200), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 69/182 (38%), Positives = 97/182 (53%), Gaps = 6/182 (3%)
Query 36 DCSHLKLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D S +L +P+ D TN+ L+L NQL+ LP F + + LT LD+ N + L
Sbjct 110 DLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNGVFDKLTSLTFLDLSTNQLQSLPN 169
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITL 152
+ KL L+ L+L+HN+L L + F T+LT L L N +Q + N F K NL L
Sbjct 170 GVFDKLTNLRELHLEHNQLQSLPNGVFDKLTSLTTLFLQWNQLQSLPNGVFDKLTNLEKL 229
Query 153 DLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
DL+ N L S G +L NL+ LLL NN++Q+L + D SL + LS N + E
Sbjct 230 DLTGNQLQSLPNGVFDKLTNLKILLLDNNQLQSLPNGVFDKLK--SLTTVGLSGN-LWEC 286
Query 213 SP 214
SP
Sbjct 287 SP 288
Score = 66.2 bits (160), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 78/300 (26%), Positives = 125/300 (42%), Gaps = 44/300 (15%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L N++ + + F L L L L N++ Q L + L + E+ LS N+ L
Sbjct 37 LSLRHNQLQSLPNGVFDKLTQLTWLHLDHNQL-QSLPNGVFDKLTKLTELILSSNQLQSL 95
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
+F + +LQ L L L+++ + F L NL L L +N + ++ + + + L
Sbjct 96 PNGTFDKLTNLQNLDLSFNQLQSLPNGV--FDKLTNLQTLHLRSNQLQSLPNGVFDKLTS 153
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L LDL N L L P G L L LH LE N +P VF L L +
Sbjct 154 LTFLDLSTNQLQSL-----PNGVFDKLTNLRELH---LEHNQLQSLPNGVFDKLTSLTTL 205
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP------------------- 632
L N L +LP VF+ +L+ L+L N + S+ VF
Sbjct 206 FLQWNQLQSLPNGVFDKLTNLEKLDLTGNQLQSLPNGVFDKLTNLKILLLDNNQLQSLPN 265
Query 633 ----AFRNLTELDMRFNPFDCT---CESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
++LT + + N ++C+ C +W ++ +I LC++P H G
Sbjct 266 GVFDKLKSLTTVGLSGNLWECSPRVCALASWLGSFQGRWEHSI-------LCHSPDHTQG 318
Score = 65.5 bits (158), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 83/272 (31%), Positives = 133/272 (49%), Gaps = 19/272 (7%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
S L L L NQ++ G F + +L L L++ QL SL + +L T + L LS
Sbjct 32 SQLLGLSLRHNQLQSLPNGVFDKLTQLTWLHLDHNQL-QSLPNGVFDKL--TKLTELILS 88
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
++QL + N TF K TNL LDLS+N L + N F L L+ L N +Q L +
Sbjct 89 SNQLQSLPNGTFD--KLTNLQNLDLSFNQLQSLPNGVFDKLTNLQTLHLRSNQLQSLPNG 146
Query 317 SLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFT 376
L ++ +L+L + L SLP + F L L L++E N + + + +F
Sbjct 147 VFDKLTSLTFLDLSTN------QLQSLP---NGVFDKLTNLRELHLEHNQLQSLPNGVFD 197
Query 377 GLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVL 436
L +L L L + L++L N F L + L L+LT N++ + + F L +L++L
Sbjct 198 KLTSLTTLFL--QWNQLQSLPNGVFDKLTN--LEKLDLTGNQLQSLPNGVFDKLTNLKIL 253
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L N++ Q L + L+++ + LS N +
Sbjct 254 LLDNNQL-QSLPNGVFDKLKSLTTVGLSGNLW 284
Score = 58.9 bits (141), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 55/188 (29%), Positives = 88/188 (47%), Gaps = 11/188 (6%)
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
+ + L +N+ L F + L L L L+++ + F L LT L LS+N
Sbjct 34 LLGLSLRHNQLQSLPNGVFDKLTQLTWLHLDHNQLQSLPNGV--FDKLTKLTELILSSNQ 91
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI 577
+ ++ + + L L+ LDL N L L P L++L L+L SN +
Sbjct 92 LQSLPNGTFDKLTNLQNLDLSFNQLQSL--------PNGVFDKLTNLQTLHLRSNQLQSL 143
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNL 637
P VF L L +DL N L +LP VF+ +L+ L+L+ N + S+ VF +L
Sbjct 144 PNGVFDKLTSLTFLDLSTNQLQSLPNGVFDKLTNLRELHLEHNQLQSLPNGVFD-KLTSL 202
Query 638 TELDMRFN 645
T L +++N
Sbjct 203 TTLFLQWN 210
Score = 39.7 bits (91), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 33/98 (34%), Positives = 42/98 (43%), Gaps = 7/98 (7%)
Query 548 HANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
H+ P G L GLS L N +P VF L +L + L N L +LP VF+
Sbjct 24 HSVPNGLPSQLLGLS------LRHNQLQSLPNGVFDKLTQLTWLHLDHNQLQSLPNGVFD 77
Query 608 NQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L L L N + S+ F NL LD+ FN
Sbjct 78 KLTKLTELILSSNQLQSLPNGTFD-KLTNLQNLDLSFN 114
>3rg1_G J CD180 molecule
Length=612
Score = 105 bits (263), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 174/680 (26%), Positives = 282/680 (41%), Gaps = 100/680 (15%)
Query 27 KCTV--SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
KCT + +C +L L ++PD LP VL + N L + F+R L LD+
Sbjct 6 KCTEKEGNRTYNCENLGLREIPDTLPNTTEVLEFSFNFLPTIQNTTFSRLINLIFLDLTR 65
Query 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
I+ + + Q L + L N L +++ + L L L I ++ P
Sbjct 66 CQINWVHEDTFQSHHQLNTIVLTGNPLIFMAETSLTGPKFLKHLFLTQTGISNLEFIPVH 125
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
+NL +L L N +SS L +NL+ L NN I + ++ + ++ L
Sbjct 126 NLENLESLHLGSNHISSINLPENFPTQNLKVLDFQNNAIHYISRKDTNSLEQATNLSLNF 185
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
+ N IK PG F I ++F +++ G SL NL +
Sbjct 186 NGNDIKGIEPGAF--ISKIF----QSLKFGGSL--------------NLFI--------- 216
Query 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL--F 322
F GL+ + L L WL E + Q+L S + GL
Sbjct 217 --IFKGLQNSTLQSL----------------WLGTFED-----TDDQYLTSATFEGLCDM 253
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKC---LEHLNMEDNDIPGIKSNMFTGLI 379
+V +NL++ + D S +C ++ L++ + G+ S + G+
Sbjct 254 SVESINLQKH------------RFSDLSSSTFRCFTRVQELDLTAAHLNGLPSGI-EGMN 300
Query 380 NLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE--SDAFSWLGHLEVL 436
+LK L L +NSF L + +F SL L+I K + K++ + L +L+ L
Sbjct 301 SLKKLVLNANSFDQLCQINAASFPSL--RDLYI----KGNMRKLDLGTRCLEKLENLQKL 354
Query 437 DLGLNEI-GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV 495
DL ++I + + + L ++ + LSYN+ L L +F P L+ L + L +V
Sbjct 355 DLSHSDIEASDCCNLQLKNLRHLQYLNLSYNEPLGLEDQAFKECPQLELLDVAFTHL-HV 413
Query 496 DSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPI 555
+ SPFQ L L +L+LS+ + N +L GL+ L L+LQ N+ G I
Sbjct 414 KAPHSPFQNLHLLRVLNLSHCLLDTSNQHLLAGLQDLRHLNLQGNSFQ--------DGSI 465
Query 556 Y---FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
L+ + L IL L S I + F L + +DL N+L ++ L
Sbjct 466 SKTNLLQMVGSLEILILSSCNLLSIDQQAFHGLRNVNHLDLSHNSLTGDSMDALSHLKGL 525
Query 613 KSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELS 672
LN+ N I + + PA + +++ NP DCTC +I F+ W E + E S
Sbjct 526 Y-LNMASNNIRIIPPHLL-PALSQQSIINLSHNPLDCTCSNI-HFITWYKENLHKL-EDS 581
Query 673 SHYLCNTPPHYHGFPVRLFD 692
C PP G V+L D
Sbjct 582 EETTCANPPSLRG--VKLSD 599
>3rg1_H N CD180 molecule
Length=612
Score = 105 bits (263), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 174/680 (26%), Positives = 282/680 (41%), Gaps = 100/680 (15%)
Query 27 KCTV--SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
KCT + +C +L L ++PD LP VL + N L + F+R L LD+
Sbjct 6 KCTEKEGNRTYNCENLGLREIPDTLPNTTEVLEFSFNFLPTIQNTTFSRLINLIFLDLTR 65
Query 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
I+ + + Q L + L N L +++ + L L L I ++ P
Sbjct 66 CQINWVHEDTFQSHHQLNTIVLTGNPLIFMAETSLTGPKFLKHLFLTQTGISNLEFIPVH 125
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
+NL +L L N +SS L +NL+ L NN I + ++ + ++ L
Sbjct 126 NLENLESLHLGSNHISSINLPENFPTQNLKVLDFQNNAIHYISRKDTNSLEQATNLSLNF 185
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
+ N IK PG F I ++F +++ G SL NL +
Sbjct 186 NGNDIKGIEPGAF--ISKIF----QSLKFGGSL--------------NLFI--------- 216
Query 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL--F 322
F GL+ + L L WL E + Q+L S + GL
Sbjct 217 --IFKGLQNSTLQSL----------------WLGTFED-----TDDQYLTSATFEGLCDM 253
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKC---LEHLNMEDNDIPGIKSNMFTGLI 379
+V +NL++ + D S +C ++ L++ + G+ S + G+
Sbjct 254 SVESINLQKH------------RFSDLSSSTFRCFTRVQELDLTAAHLNGLPSGI-EGMN 300
Query 380 NLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE--SDAFSWLGHLEVL 436
+LK L L +NSF L + +F SL L+I K + K++ + L +L+ L
Sbjct 301 SLKKLVLNANSFDQLCQINAASFPSL--RDLYI----KGNMRKLDLGTRCLEKLENLQKL 354
Query 437 DLGLNEI-GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV 495
DL ++I + + + L ++ + LSYN+ L L +F P L+ L + L +V
Sbjct 355 DLSHSDIEASDCCNLQLKNLRHLQYLNLSYNEPLGLEDQAFKECPQLELLDVAFTHL-HV 413
Query 496 DSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPI 555
+ SPFQ L L +L+LS+ + N +L GL+ L L+LQ N+ G I
Sbjct 414 KAPHSPFQNLHLLRVLNLSHCLLDTSNQHLLAGLQDLRHLNLQGNSFQ--------DGSI 465
Query 556 Y---FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
L+ + L IL L S I + F L + +DL N+L ++ L
Sbjct 466 SKTNLLQMVGSLEILILSSCNLLSIDQQAFHGLRNVNHLDLSHNSLTGDSMDALSHLKGL 525
Query 613 KSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELS 672
LN+ N I + + PA + +++ NP DCTC +I F+ W E + E S
Sbjct 526 Y-LNMASNNIRIIPPHLL-PALSQQSIINLSHNPLDCTCSNI-HFITWYKENLHKL-EDS 581
Query 673 SHYLCNTPPHYHGFPVRLFD 692
C PP G V+L D
Sbjct 582 EETTCANPPSLRG--VKLSD 599
>3rg1_E B CD180 molecule
Length=612
Score = 105 bits (263), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 174/680 (26%), Positives = 282/680 (41%), Gaps = 100/680 (15%)
Query 27 KCTV--SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
KCT + +C +L L ++PD LP VL + N L + F+R L LD+
Sbjct 6 KCTEKEGNRTYNCENLGLREIPDTLPNTTEVLEFSFNFLPTIQNTTFSRLINLIFLDLTR 65
Query 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
I+ + + Q L + L N L +++ + L L L I ++ P
Sbjct 66 CQINWVHEDTFQSHHQLNTIVLTGNPLIFMAETSLTGPKFLKHLFLTQTGISNLEFIPVH 125
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
+NL +L L N +SS L +NL+ L NN I + ++ + ++ L
Sbjct 126 NLENLESLHLGSNHISSINLPENFPTQNLKVLDFQNNAIHYISRKDTNSLEQATNLSLNF 185
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
+ N IK PG F I ++F +++ G SL NL +
Sbjct 186 NGNDIKGIEPGAF--ISKIF----QSLKFGGSL--------------NLFI--------- 216
Query 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL--F 322
F GL+ + L L WL E + Q+L S + GL
Sbjct 217 --IFKGLQNSTLQSL----------------WLGTFED-----TDDQYLTSATFEGLCDM 253
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKC---LEHLNMEDNDIPGIKSNMFTGLI 379
+V +NL++ + D S +C ++ L++ + G+ S + G+
Sbjct 254 SVESINLQKH------------RFSDLSSSTFRCFTRVQELDLTAAHLNGLPSGI-EGMN 300
Query 380 NLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE--SDAFSWLGHLEVL 436
+LK L L +NSF L + +F SL L+I K + K++ + L +L+ L
Sbjct 301 SLKKLVLNANSFDQLCQINAASFPSL--RDLYI----KGNMRKLDLGTRCLEKLENLQKL 354
Query 437 DLGLNEI-GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV 495
DL ++I + + + L ++ + LSYN+ L L +F P L+ L + L +V
Sbjct 355 DLSHSDIEASDCCNLQLKNLRHLQYLNLSYNEPLGLEDQAFKECPQLELLDVAFTHL-HV 413
Query 496 DSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPI 555
+ SPFQ L L +L+LS+ + N +L GL+ L L+LQ N+ G I
Sbjct 414 KAPHSPFQNLHLLRVLNLSHCLLDTSNQHLLAGLQDLRHLNLQGNSFQ--------DGSI 465
Query 556 Y---FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
L+ + L IL L S I + F L + +DL N+L ++ L
Sbjct 466 SKTNLLQMVGSLEILILSSCNLLSIDQQAFHGLRNVNHLDLSHNSLTGDSMDALSHLKGL 525
Query 613 KSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELS 672
LN+ N I + + PA + +++ NP DCTC +I F+ W E + E S
Sbjct 526 Y-LNMASNNIRIIPPHLL-PALSQQSIINLSHNPLDCTCSNI-HFITWYKENLHKL-EDS 581
Query 673 SHYLCNTPPHYHGFPVRLFD 692
C PP G V+L D
Sbjct 582 EETTCANPPSLRG--VKLSD 599
>3rg1_F F CD180 molecule
Length=612
Score = 105 bits (263), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 174/680 (26%), Positives = 282/680 (41%), Gaps = 100/680 (15%)
Query 27 KCTV--SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
KCT + +C +L L ++PD LP VL + N L + F+R L LD+
Sbjct 6 KCTEKEGNRTYNCENLGLREIPDTLPNTTEVLEFSFNFLPTIQNTTFSRLINLIFLDLTR 65
Query 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
I+ + + Q L + L N L +++ + L L L I ++ P
Sbjct 66 CQINWVHEDTFQSHHQLNTIVLTGNPLIFMAETSLTGPKFLKHLFLTQTGISNLEFIPVH 125
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
+NL +L L N +SS L +NL+ L NN I + ++ + ++ L
Sbjct 126 NLENLESLHLGSNHISSINLPENFPTQNLKVLDFQNNAIHYISRKDTNSLEQATNLSLNF 185
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
+ N IK PG F I ++F +++ G SL NL +
Sbjct 186 NGNDIKGIEPGAF--ISKIF----QSLKFGGSL--------------NLFI--------- 216
Query 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL--F 322
F GL+ + L L WL E + Q+L S + GL
Sbjct 217 --IFKGLQNSTLQSL----------------WLGTFED-----TDDQYLTSATFEGLCDM 253
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKC---LEHLNMEDNDIPGIKSNMFTGLI 379
+V +NL++ + D S +C ++ L++ + G+ S + G+
Sbjct 254 SVESINLQKH------------RFSDLSSSTFRCFTRVQELDLTAAHLNGLPSGI-EGMN 300
Query 380 NLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE--SDAFSWLGHLEVL 436
+LK L L +NSF L + +F SL L+I K + K++ + L +L+ L
Sbjct 301 SLKKLVLNANSFDQLCQINAASFPSL--RDLYI----KGNMRKLDLGTRCLEKLENLQKL 354
Query 437 DLGLNEI-GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV 495
DL ++I + + + L ++ + LSYN+ L L +F P L+ L + L +V
Sbjct 355 DLSHSDIEASDCCNLQLKNLRHLQYLNLSYNEPLGLEDQAFKECPQLELLDVAFTHL-HV 413
Query 496 DSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPI 555
+ SPFQ L L +L+LS+ + N +L GL+ L L+LQ N+ G I
Sbjct 414 KAPHSPFQNLHLLRVLNLSHCLLDTSNQHLLAGLQDLRHLNLQGNSFQ--------DGSI 465
Query 556 Y---FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
L+ + L IL L S I + F L + +DL N+L ++ L
Sbjct 466 SKTNLLQMVGSLEILILSSCNLLSIDQQAFHGLRNVNHLDLSHNSLTGDSMDALSHLKGL 525
Query 613 KSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELS 672
LN+ N I + + PA + +++ NP DCTC +I F+ W E + E S
Sbjct 526 Y-LNMASNNIRIIPPHLL-PALSQQSIINLSHNPLDCTCSNI-HFITWYKENLHKL-EDS 581
Query 673 SHYLCNTPPHYHGFPVRLFD 692
C PP G V+L D
Sbjct 582 EETTCANPPSLRG--VKLSD 599
>4li2_A A Leucine-rich repeat-containing G-protein coupled receptor
4
Length=432
Score = 103 bits (258), Expect = 4e-22, Method: Compositional matrix adjust.
Identities = 125/439 (28%), Positives = 197/439 (45%), Gaps = 42/439 (10%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
ADCS L VPD L L+L+ N + +LP F + L L + N +S + P
Sbjct 21 ADCSGKGLVTVPDGLSVFTHSLDLSMNNITKLPEGAFKGFPYLEELRLAGNDLSIIHPMA 80
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + ++ +L L L +N I + + F L L L
Sbjct 81 LSGLKELKVLTLQNNQLKTVPSESLKGLVSLQSLRLDANHIVTVPEDSFEGLVQLRHLWL 140
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L +LQ L L+ NKI + F+N SSL L L +N+I+
Sbjct 141 DDNSLTEVPIRPLSNLPSLQALTLALNKISHIPDYA---FSNLSSLVVLHLHNNKIRTLG 197
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
P FH + L L L NN+ P L +++ L ++ ++ + F +
Sbjct 198 PHSFHGLDNLEALDLNYNNLIDFPDSIRSL------PNLKELGFHSNSITIIPDGAF--V 249
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL-NLK 330
K L + L N L+ VGN +F L L + + G NV++ NL
Sbjct 250 KNPLLRTIHLYDNPLSFVGNSAFQNLSDLHFLIIR-------------GASNVQWFPNLT 296
Query 331 RSFTKQSISLASLPKIDDFSFQWL---KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
+ +S++L KI ++ K L L++ N+I + F G +L+ + L
Sbjct 297 GTNNLESLTLTGT-KIRSIPIKFCQEQKMLRTLDLSYNEISALVG--FEGCSSLEEVYLQ 353
Query 388 NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQEL 447
N+ ++ + NETF LA L +L+L++N+I I +AF L L LDL N +L
Sbjct 354 NN--QIQEVQNETFQGLA--ALRMLDLSRNRIHTIHKEAFVTLKALTNLDLSFN----DL 405
Query 448 TGQEWRGLENIFEIYLSYN 466
T GL + ++ L+ N
Sbjct 406 TAFPTAGLHGLNQLKLTGN 424
Score = 77.8 bits (190), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 108/413 (26%), Positives = 174/413 (42%), Gaps = 74/413 (18%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDLS NN+ + +F P LE L N++ + +L GL ++ L L+ +
Sbjct 42 LDLSMNNITKLPEGAFKGFPYLEELRLAGNDLSIIHPMALSGLKELKVLTLQNN------ 95
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
L + S + L L+ L ++ N I + + F GL+ L++L L ++ +LT
Sbjct 96 ---QLKTVPSESLKGLVSLQSLRLDANHIVTVPEDSFEGLVQLRHLWLDDN-----SLTE 147
Query 399 ETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN 457
L++ P L L L NKIS I AFS L L VL L N+I + L + GL+N
Sbjct 148 VPIRPLSNLPSLQALTLALNKISHIPDYAFSNLSSLVVLHLHNNKI-RTLGPHSFHGLDN 206
Query 458 IFEIYLSYN---------------KYLQLTRNSFALVPS---LQRLMLRRVALKNVDSS- 498
+ + L+YN K L NS ++P ++ +LR + L + S
Sbjct 207 LEALDLNYNNLIDFPDSIRSLPNLKELGFHSNSITIIPDGAFVKNPLLRTIHLYDNPLSF 266
Query 499 --PSPFQPL-----------------------RNLTILDLSNNNIANINDDMLEGLEKLE 533
S FQ L NL L L+ I +I + + L
Sbjct 267 VGNSAFQNLSDLHFLIIRGASNVQWFPNLTGTNNLESLTLTGTKIRSIPIKFCQEQKMLR 326
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LDL +N ++ L +G S L + L++N E+ E F+ L L+++DL
Sbjct 327 TLDLSYNEISALVG----------FEGCSSLEEVYLQNNQIQEVQNETFQGLAALRMLDL 376
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNP 646
N ++T+ F +L +L+L N +T+ L +L + NP
Sbjct 377 SRNRIHTIHKEAFVTLKALTNLDLSFNDLTAFPTA----GLHGLNQLKLTGNP 425
>3rg1_D M CD180 molecule
Length=612
Score = 105 bits (261), Expect = 6e-22, Method: Compositional matrix adjust.
Identities = 171/673 (25%), Positives = 278/673 (41%), Gaps = 98/673 (15%)
Query 27 KCTV--SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
KCT + +C +L L ++PD LP VL + N L + F+R L LD+
Sbjct 6 KCTEKEGNRTYNCENLGLREIPDTLPNTTEVLEFSFNFLPTIQNTTFSRLINLIFLDLTR 65
Query 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
I+ + + Q L + L N L +++ + L L L I ++ P
Sbjct 66 CQINWVHEDTFQSHHQLNTIVLTGNPLIFMAETSLTGPKFLKHLFLTQTGISNLEFIPVH 125
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
+NL +L L N +SS L +NL+ L NN I + ++ + ++ L
Sbjct 126 NLENLESLHLGSNHISSINLPENFPTQNLKVLDFQNNAIHYISRKDTNSLEQATNLSLNF 185
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
+ N IK PG F I ++F +++ G SL NL +
Sbjct 186 NGNDIKGIEPGAF--ISKIF----QSLKFGGSL--------------NLFI--------- 216
Query 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL--F 322
F GL+ + L L WL E + Q+L S + GL
Sbjct 217 --IFKGLQNSTLQSL----------------WLGTFED-----TDDQYLTSATFEGLCDM 253
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKC---LEHLNMEDNDIPGIKSNMFTGLI 379
+V +NL++ + D S +C ++ L++ + G+ S + G+
Sbjct 254 SVESINLQKH------------RFSDLSSSTFRCFTRVQELDLTAAHLNGLPSGI-EGMN 300
Query 380 NLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE--SDAFSWLGHLEVL 436
+LK L L +NSF L + +F SL L+I K + K++ + L +L+ L
Sbjct 301 SLKKLVLNANSFDQLCQINAASFPSL--RDLYI----KGNMRKLDLGTRCLEKLENLQKL 354
Query 437 DLGLNEI-GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV 495
DL ++I + + + L ++ + LSYN+ L L +F P L+ L + L +V
Sbjct 355 DLSHSDIEASDCCNLQLKNLRHLQYLNLSYNEPLGLEDQAFKECPQLELLDVAFTHL-HV 413
Query 496 DSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPI 555
+ SPFQ L L +L+LS+ + N +L GL+ L L+LQ N+ G I
Sbjct 414 KAPHSPFQNLHLLRVLNLSHCLLDTSNQHLLAGLQDLRHLNLQGNSFQ--------DGSI 465
Query 556 Y---FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
L+ + L IL L S I + F L + +DL N+L ++ L
Sbjct 466 SKTNLLQMVGSLEILILSSCNLLSIDQQAFHGLRNVNHLDLSHNSLTGDSMDALSHLKGL 525
Query 613 KSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELS 672
LN+ N I + + PA + +++ NP DCTC +I F+ W E + E S
Sbjct 526 Y-LNMASNNIRIIPPHLL-PALSQQSIINLSHNPLDCTCSNI-HFITWYKENLHKL-EDS 581
Query 673 SHYLCNTPPHYHG 685
C PP G
Sbjct 582 EETTCANPPSLRG 594
>3rg1_A A CD180 molecule
Length=612
Score = 105 bits (261), Expect = 7e-22, Method: Compositional matrix adjust.
Identities = 171/673 (25%), Positives = 278/673 (41%), Gaps = 98/673 (15%)
Query 27 KCTV--SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
KCT + +C +L L ++PD LP VL + N L + F+R L LD+
Sbjct 6 KCTEKEGNRTYNCENLGLREIPDTLPNTTEVLEFSFNFLPTIQNTTFSRLINLIFLDLTR 65
Query 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
I+ + + Q L + L N L +++ + L L L I ++ P
Sbjct 66 CQINWVHEDTFQSHHQLNTIVLTGNPLIFMAETSLTGPKFLKHLFLTQTGISNLEFIPVH 125
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
+NL +L L N +SS L +NL+ L NN I + ++ + ++ L
Sbjct 126 NLENLESLHLGSNHISSINLPENFPTQNLKVLDFQNNAIHYISRKDTNSLEQATNLSLNF 185
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
+ N IK PG F I ++F +++ G SL NL +
Sbjct 186 NGNDIKGIEPGAF--ISKIF----QSLKFGGSL--------------NLFI--------- 216
Query 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL--F 322
F GL+ + L L WL E + Q+L S + GL
Sbjct 217 --IFKGLQNSTLQSL----------------WLGTFED-----TDDQYLTSATFEGLCDM 253
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKC---LEHLNMEDNDIPGIKSNMFTGLI 379
+V +NL++ + D S +C ++ L++ + G+ S + G+
Sbjct 254 SVESINLQKH------------RFSDLSSSTFRCFTRVQELDLTAAHLNGLPSGI-EGMN 300
Query 380 NLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE--SDAFSWLGHLEVL 436
+LK L L +NSF L + +F SL L+I K + K++ + L +L+ L
Sbjct 301 SLKKLVLNANSFDQLCQINAASFPSL--RDLYI----KGNMRKLDLGTRCLEKLENLQKL 354
Query 437 DLGLNEI-GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV 495
DL ++I + + + L ++ + LSYN+ L L +F P L+ L + L +V
Sbjct 355 DLSHSDIEASDCCNLQLKNLRHLQYLNLSYNEPLGLEDQAFKECPQLELLDVAFTHL-HV 413
Query 496 DSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPI 555
+ SPFQ L L +L+LS+ + N +L GL+ L L+LQ N+ G I
Sbjct 414 KAPHSPFQNLHLLRVLNLSHCLLDTSNQHLLAGLQDLRHLNLQGNSFQ--------DGSI 465
Query 556 Y---FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
L+ + L IL L S I + F L + +DL N+L ++ L
Sbjct 466 SKTNLLQMVGSLEILILSSCNLLSIDQQAFHGLRNVNHLDLSHNSLTGDSMDALSHLKGL 525
Query 613 KSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELS 672
LN+ N I + + PA + +++ NP DCTC +I F+ W E + E S
Sbjct 526 Y-LNMASNNIRIIPPHLL-PALSQQSIINLSHNPLDCTCSNI-HFITWYKENLHKL-EDS 581
Query 673 SHYLCNTPPHYHG 685
C PP G
Sbjct 582 EETTCANPPSLRG 594
>3rg1_B E CD180 molecule
Length=612
Score = 105 bits (261), Expect = 7e-22, Method: Compositional matrix adjust.
Identities = 171/673 (25%), Positives = 278/673 (41%), Gaps = 98/673 (15%)
Query 27 KCTV--SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
KCT + +C +L L ++PD LP VL + N L + F+R L LD+
Sbjct 6 KCTEKEGNRTYNCENLGLREIPDTLPNTTEVLEFSFNFLPTIQNTTFSRLINLIFLDLTR 65
Query 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
I+ + + Q L + L N L +++ + L L L I ++ P
Sbjct 66 CQINWVHEDTFQSHHQLNTIVLTGNPLIFMAETSLTGPKFLKHLFLTQTGISNLEFIPVH 125
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
+NL +L L N +SS L +NL+ L NN I + ++ + ++ L
Sbjct 126 NLENLESLHLGSNHISSINLPENFPTQNLKVLDFQNNAIHYISRKDTNSLEQATNLSLNF 185
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
+ N IK PG F I ++F +++ G SL NL +
Sbjct 186 NGNDIKGIEPGAF--ISKIF----QSLKFGGSL--------------NLFI--------- 216
Query 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL--F 322
F GL+ + L L WL E + Q+L S + GL
Sbjct 217 --IFKGLQNSTLQSL----------------WLGTFED-----TDDQYLTSATFEGLCDM 253
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKC---LEHLNMEDNDIPGIKSNMFTGLI 379
+V +NL++ + D S +C ++ L++ + G+ S + G+
Sbjct 254 SVESINLQKH------------RFSDLSSSTFRCFTRVQELDLTAAHLNGLPSGI-EGMN 300
Query 380 NLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE--SDAFSWLGHLEVL 436
+LK L L +NSF L + +F SL L+I K + K++ + L +L+ L
Sbjct 301 SLKKLVLNANSFDQLCQINAASFPSL--RDLYI----KGNMRKLDLGTRCLEKLENLQKL 354
Query 437 DLGLNEI-GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV 495
DL ++I + + + L ++ + LSYN+ L L +F P L+ L + L +V
Sbjct 355 DLSHSDIEASDCCNLQLKNLRHLQYLNLSYNEPLGLEDQAFKECPQLELLDVAFTHL-HV 413
Query 496 DSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPI 555
+ SPFQ L L +L+LS+ + N +L GL+ L L+LQ N+ G I
Sbjct 414 KAPHSPFQNLHLLRVLNLSHCLLDTSNQHLLAGLQDLRHLNLQGNSFQ--------DGSI 465
Query 556 Y---FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
L+ + L IL L S I + F L + +DL N+L ++ L
Sbjct 466 SKTNLLQMVGSLEILILSSCNLLSIDQQAFHGLRNVNHLDLSHNSLTGDSMDALSHLKGL 525
Query 613 KSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELS 672
LN+ N I + + PA + +++ NP DCTC +I F+ W E + E S
Sbjct 526 Y-LNMASNNIRIIPPHLL-PALSQQSIINLSHNPLDCTCSNI-HFITWYKENLHKL-EDS 581
Query 673 SHYLCNTPPHYHG 685
C PP G
Sbjct 582 EETTCANPPSLRG 594
>4kt1_A A Leucine-rich repeat-containing G-protein coupled receptor
4
Length=504
Score = 103 bits (258), Expect = 9e-22, Method: Compositional matrix adjust.
Identities = 132/451 (29%), Positives = 199/451 (44%), Gaps = 38/451 (8%)
Query 20 LCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTS 79
LCA+ + C V DCS LT VP+ L L+++ N + +LP F + L
Sbjct 3 LCAAPCS-CDGDRRV-DCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEE 60
Query 80 LDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
L + N +S + P+ L LKVL LQ+N+L + + + L L L +N I +
Sbjct 61 LQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVP 120
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SS 198
+ F L L L N L+ + L LQ L L+ NKI ++ F N SS
Sbjct 121 EDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFA---FTNLSS 177
Query 199 LKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLG--PSLTEKLCLELANTSIRNLSLS 256
L L L +N+I+ S CF + L L LN LG P + L S++ L
Sbjct 178 LVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKAL------PSLKELGFH 231
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
++ +S + F G L + L N L+ VGN +F L L + ++ F +
Sbjct 232 SNSISVIPDGAFDGNPL--LRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPN 289
Query 317 SLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFT 376
L G ++ L L T IS I + Q K L L++ N+I + S F
Sbjct 290 -LTGTVHLESLTL----TGTKIS-----SIPNNLCQEQKMLRTLDLSYNNIRDLPS--FN 337
Query 377 GLINLKYLSLS-NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEV 435
G L+ +SL N ++ T + +S L IL+L++N I +I S AF+ LG +
Sbjct 338 GCHALEEISLQRNQIYQIKEGTFQGLIS-----LRILDLSRNLIHEIHSRAFATLGPITN 392
Query 436 LDLGLNEIGQELTGQEWRGLENIFEIYLSYN 466
LD+ N ELT GL + ++ L N
Sbjct 393 LDVSFN----ELTSFPTEGLNGLNQLKLVGN 419
Score = 90.9 bits (224), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 102/390 (26%), Positives = 171/390 (44%), Gaps = 51/390 (13%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LD+S NN+ + D+F P LE L N++ + +L GL ++ L L+ + K
Sbjct 37 LDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 96
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
S A + L L+ L ++ N I + + F GL+ L++L L ++ +LT
Sbjct 97 SEA---------IRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDN-----SLTE 142
Query 399 ETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN 457
L++ P L L L NKIS I AF+ L L VL L N+I + L+ + GL+N
Sbjct 143 VPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKI-RSLSQHCFDGLDN 201
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
+ + L+YN + + AL PSL+ L ++ + PL L + L +N
Sbjct 202 LETLDLNYNNLGEFPQAIKAL-PSLKELGFHSNSISVIPDGAFDGNPL--LRTIHLYDNP 258
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI 577
++ + + L L L ++ ++ + + + L G HL L L I
Sbjct 259 LSFVGNSAFHNLSDLHSLVIRGASMVQQFPN---------LTGTVHLESLTLTGTKISSI 309
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPA----------------------SVFNNQVSLKSL 615
P + ++ L+ +DL NN+ LP+ F +SL+ L
Sbjct 310 PNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRIL 369
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
+L +NLI + + F +T LD+ FN
Sbjct 370 DLSRNLIHEIHSRAFA-TLGPITNLDVSFN 398
Score = 67.0 bits (162), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 114/431 (26%), Positives = 185/431 (43%), Gaps = 66/431 (15%)
Query 139 KNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSS 198
KN PF+++ L L+ N LS L+ L+ L L NN+++ + SE I S+
Sbjct 53 KNFPFLEE-----LQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEA--IRGLSA 105
Query 199 LKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNLSLSN 257
L+ L L +N I F + +L L+L++ SLTE L+N +++ L+L+
Sbjct 106 LQSLRLDANHITSVPEDSFEGLVQLRHLWLDDN----SLTEVPVHPLSNLPTLQALTLAL 161
Query 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
+++S+ + F L ++L +L L N + + F L LE L YNN+ F +
Sbjct 162 NKISSIPDFAFTNL--SSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGE-FPQA 218
Query 318 LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTG 377
+ L +++ L F SIS+ I D +F L +++ DN + + ++ F
Sbjct 219 IKALPSLKEL----GFHSNSISV-----IPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHN 269
Query 378 LINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
L +L L + + + ++ N T H L L LT KIS I ++ L LD
Sbjct 270 LSDLHSLVIRGA-SMVQQFPNLT--GTVH--LESLTLTGTKISSIPNNLCQEQKMLRTLD 324
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS 497
L N I ++L + G + EI L N+ Q+ +F
Sbjct 325 LSYNNI-RDLP--SFNGCHALEEISLQRNQIYQIKEGTF--------------------- 360
Query 498 SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF 557
Q L +L ILDLS N I I+ L + LD+ N L P
Sbjct 361 -----QGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSF--------PTEG 407
Query 558 LKGLSHLHILN 568
L GL+ L ++
Sbjct 408 LNGLNQLKLVG 418
>3fxi_A A Toll-like receptor 4
Length=605
Score = 103 bits (258), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 177/666 (27%), Positives = 285/666 (43%), Gaps = 99/666 (15%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 14 CMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 73
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 74 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 133
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFAN--SSLKKLELSSNQIKEFS 213
N + S KL L NL+ L LS+NKIQ++ +L + L+LS N +
Sbjct 134 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 193
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
PG F I RL L L N K C++ LA + L L L +
Sbjct 194 PGAFKEI-RLHKLTLRN-NFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSAL 251
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
GL NLT+ + L L+Y+ ++I LF + L NV
Sbjct 252 EGL--CNLTIEEFR--------------LAYLDYYL---DDIIDLF----NCLTNV---- 284
Query 329 LKRSFTKQSISLASLPKIDDFS--FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
SF+ S+++ ++ DFS F W + LE +N + P +K
Sbjct 285 --SSFSLVSVTIE---RVKDFSYNFGW-QHLELVNCKFGQFPTLK--------------- 323
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG-Q 445
L++L TF S N N S+++ L LE LDL N + +
Sbjct 324 ------LKSLKRLTFTS---------NKGGNAFSEVD------LPSLEFLDLSRNGLSFK 362
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
Q G ++ + LS+N + ++ N F + L+ L + LK + S S F L
Sbjct 363 GCCSQSDFGTTSLKYLDLSFNGVITMSSN-FLGLEQLEHLDFQHSNLKQM-SEFSVFLSL 420
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
RNL LD+S+ + + + GL LE+L + N+ + P F + L +L
Sbjct 421 RNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFL------PDIFTE-LRNLT 473
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNN---LNTLPASVFNNQVSLKSLNLQKNLI 622
L+L +++ F L L+++++ NN L+T P N SL+ L+ N I
Sbjct 474 FLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLN---SLQVLDYSLNHI 530
Query 623 TSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPH 682
+ +K+ +L L++ N F CTCE + F+ WI + + E+ C TP
Sbjct 531 MTSKKQELQHFPSSLAFLNLTQNDFACTCEHQS-FLQWIKDQRQLLVEV-ERMECATPSD 588
Query 683 YHGFPV 688
G PV
Sbjct 589 KQGMPV 594
>3fxi_B B Toll-like receptor 4
Length=605
Score = 103 bits (258), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 177/666 (27%), Positives = 285/666 (43%), Gaps = 99/666 (15%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 14 CMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 73
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 74 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 133
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFAN--SSLKKLELSSNQIKEFS 213
N + S KL L NL+ L LS+NKIQ++ +L + L+LS N +
Sbjct 134 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 193
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
PG F I RL L L N K C++ LA + L L L +
Sbjct 194 PGAFKEI-RLHKLTLRN-NFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSAL 251
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
GL NLT+ + L L+Y+ ++I LF + L NV
Sbjct 252 EGL--CNLTIEEFR--------------LAYLDYYL---DDIIDLF----NCLTNV---- 284
Query 329 LKRSFTKQSISLASLPKIDDFS--FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
SF+ S+++ ++ DFS F W + LE +N + P +K
Sbjct 285 --SSFSLVSVTIE---RVKDFSYNFGW-QHLELVNCKFGQFPTLK--------------- 323
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG-Q 445
L++L TF S N N S+++ L LE LDL N + +
Sbjct 324 ------LKSLKRLTFTS---------NKGGNAFSEVD------LPSLEFLDLSRNGLSFK 362
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
Q G ++ + LS+N + ++ N F + L+ L + LK + S S F L
Sbjct 363 GCCSQSDFGTTSLKYLDLSFNGVITMSSN-FLGLEQLEHLDFQHSNLKQM-SEFSVFLSL 420
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
RNL LD+S+ + + + GL LE+L + N+ + P F + L +L
Sbjct 421 RNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFL------PDIFTE-LRNLT 473
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNN---LNTLPASVFNNQVSLKSLNLQKNLI 622
L+L +++ F L L+++++ NN L+T P N SL+ L+ N I
Sbjct 474 FLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLN---SLQVLDYSLNHI 530
Query 623 TSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPH 682
+ +K+ +L L++ N F CTCE + F+ WI + + E+ C TP
Sbjct 531 MTSKKQELQHFPSSLAFLNLTQNDFACTCEHQS-FLQWIKDQRQLLVEV-ERMECATPSD 588
Query 683 YHGFPV 688
G PV
Sbjct 589 KQGMPV 594
>4g8a_A A Toll-like receptor 4
Length=635
Score = 103 bits (256), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 172/664 (26%), Positives = 282/664 (42%), Gaps = 95/664 (14%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 38 CMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 97
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 98 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 157
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFAN--SSLKKLELSSNQIKEFS 213
N + S KL L NL+ L LS+NKIQ++ +L + L+LS N +
Sbjct 158 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 217
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKW 273
PG F I RL L L N L + T I+ L+ GL+
Sbjct 218 PGAFKEI-RLHKLTLRN--------NFDSLNVMKTCIQGLA---------------GLEV 253
Query 274 TNLTMLDL-SYNNLNVVGNDSFAWLPQL--EYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
L + + + NL + L L E F L Y + L G+ ++ N
Sbjct 254 HRLVLGEFRNEGNLEKFDKSALEGLCNLTIEEFRLAY------LDYYLDGIIDL--FNCL 305
Query 331 RSFTKQSISLASLPKIDDFS--FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
+ + S+ ++ ++ DFS F W + LE +N + P +K
Sbjct 306 TNVSSFSLVSVTIERVKDFSYNFGW-QHLELVNCKFGQFPTLK----------------- 347
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG-QEL 447
L++L TF S N N S+++ L LE LDL N + +
Sbjct 348 ----LKSLKRLTFTS---------NKGGNAFSEVD------LPSLEFLDLSRNGLSFKGC 388
Query 448 TGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRN 507
Q G ++ + LS+N + ++ N F + L+ L + LK + S S F LRN
Sbjct 389 CSQSDFGTISLKYLDLSFNGVITMSSN-FLGLEQLEHLDFQHSNLKQM-SEFSVFLSLRN 446
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LD+S+ + + + GL LE+L + N+ + P F + L +L L
Sbjct 447 LIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFL------PDIFTE-LRNLTFL 499
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNN---LNTLPASVFNNQVSLKSLNLQKNLITS 624
+L +++ F L L+++++ NN L+T P N SL+ L+ N I +
Sbjct 500 DLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLN---SLQVLDYSLNHIMT 556
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYH 684
+K+ +L L++ N F CTCE + F+ WI + + E+ C TP
Sbjct 557 SKKQELQHFPSSLAFLNLTQNDFACTCEHQS-FLQWIKDQRQLLVEV-ERMECATPSDKQ 614
Query 685 GFPV 688
G PV
Sbjct 615 GMPV 618
>4g8a_B B Toll-like receptor 4
Length=635
Score = 103 bits (256), Expect = 3e-21, Method: Compositional matrix adjust.
Identities = 172/664 (26%), Positives = 282/664 (42%), Gaps = 95/664 (14%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 38 CMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 97
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 98 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 157
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFAN--SSLKKLELSSNQIKEFS 213
N + S KL L NL+ L LS+NKIQ++ +L + L+LS N +
Sbjct 158 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 217
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKW 273
PG F I RL L L N L + T I+ L+ GL+
Sbjct 218 PGAFKEI-RLHKLTLRN--------NFDSLNVMKTCIQGLA---------------GLEV 253
Query 274 TNLTMLDL-SYNNLNVVGNDSFAWLPQL--EYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
L + + + NL + L L E F L Y + L G+ ++ N
Sbjct 254 HRLVLGEFRNEGNLEKFDKSALEGLCNLTIEEFRLAY------LDYYLDGIIDL--FNCL 305
Query 331 RSFTKQSISLASLPKIDDFS--FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
+ + S+ ++ ++ DFS F W + LE +N + P +K
Sbjct 306 TNVSSFSLVSVTIERVKDFSYNFGW-QHLELVNCKFGQFPTLK----------------- 347
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG-QEL 447
L++L TF S N N S+++ L LE LDL N + +
Sbjct 348 ----LKSLKRLTFTS---------NKGGNAFSEVD------LPSLEFLDLSRNGLSFKGC 388
Query 448 TGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRN 507
Q G ++ + LS+N + ++ N F + L+ L + LK + S S F LRN
Sbjct 389 CSQSDFGTISLKYLDLSFNGVITMSSN-FLGLEQLEHLDFQHSNLKQM-SEFSVFLSLRN 446
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LD+S+ + + + GL LE+L + N+ + P F + L +L L
Sbjct 447 LIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFL------PDIFTE-LRNLTFL 499
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNN---LNTLPASVFNNQVSLKSLNLQKNLITS 624
+L +++ F L L+++++ NN L+T P N SL+ L+ N I +
Sbjct 500 DLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLN---SLQVLDYSLNHIMT 556
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYH 684
+K+ +L L++ N F CTCE + F+ WI + + E+ C TP
Sbjct 557 SKKQELQHFPSSLAFLNLTQNDFACTCEHQS-FLQWIKDQRQLLVEV-ERMECATPSDKQ 614
Query 685 GFPV 688
G PV
Sbjct 615 GMPV 618
>5zsm_A B Toll-like receptor 7
Length=823
Score = 102 bits (255), Expect = 6e-21, Method: Compositional matrix adjust.
Identities = 188/717 (26%), Positives = 280/717 (39%), Gaps = 118/717 (16%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGP--SLTEKLCLELANTS 249
N L+ S N + FS I R+ G L + QL P +L L+L
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNF 386
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
I+ +LS + ++ L ++DLS N ++
Sbjct 387 IKIANLS------------MFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXX 434
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
Q L L+ RY RS + K + L++ N I
Sbjct 435 XQ-----VLEQLYYFRYDKYARSCRFKXXXXXXXXX----XXSCYKYGQTLDLSKNSIFF 485
Query 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
IKS+ F L LK L+LS + S +TL F LA L L+ + N++ + S AF
Sbjct 486 IKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNNRLDLLHSTAFEE 542
Query 430 LGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRR 489
L LEVLD+ N + E I + L++ K L++ LQ+LM+
Sbjct 543 LRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV----------LQKLMMND 583
Query 490 VALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
+ + S + LR L LD+ + N + + L KLE LD+ N+L+ L
Sbjct 584 NDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFL 643
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASV 605
G P +L L+L NG E + L L+ +DL N L T+P +
Sbjct 644 PSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERL 696
Query 606 FNNQVSLKSLNLQKNLITSVEKKVFGPAFR-------------------------NLTEL 640
N SLK+L L+ N I S+ K AF+ NL L
Sbjct 697 SNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKML 756
Query 641 DMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSCK 697
+ N F CTC+++ WFV W+ T IP L++ C P + G V D +C+
Sbjct 757 LLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTCE 812
Score = 65.1 bits (157), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 280/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIG---------------QELTGQEWRGLENI 458
L N I F L+V+DL +N+I + LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXQVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRFKXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>3j0a_B B Toll-like receptor 5
Length=844
Score = 102 bits (254), Expect = 7e-21, Method: Compositional matrix adjust.
Identities = 191/724 (26%), Positives = 305/724 (42%), Gaps = 106/724 (15%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN- 85
C+ +A LTQVP L T +L L+ N +R + A++F QL L++G
Sbjct 1 SCSFDGRIAFYRFCNLTQVPQVLNTTERLL-LSFNYIRTVTASSFPFLEQLQLLELGSQY 59
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL----MSNSIQKIKNN 141
T ++ E + LP L++L+L +++ L F +L EL L +S+++ +K+
Sbjct 60 TPLTIDKEAFRNLPNLRILDLGSSKIYFLHPDAFQGLFHLFELRLYFCGLSDAV--LKDG 117
Query 142 PFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKK 201
F K L LDLS N + S L N SLK
Sbjct 118 YFRNLKALTRLDLSKNQIRSLYLHPSFGKLN-------------------------SLKS 152
Query 202 LELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGP-SLTEKLCLELANT--SIRNLSLSNS 258
++ SSNQI C H + L G L+ L SL ++ ++ RN+ L
Sbjct 153 IDFSSNQIFLV---CEHELEPLQGKTLSFFSLAANSLYSRVSVDWGKCMNPFRNMVLEIL 209
Query 259 QLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFF---LEYNNIQHLFS 315
+S G WT +D++ N N + L + ++NI+
Sbjct 210 DVS--------GNGWT----VDITGNFSNAISKSQAFSLILAHHIMGAGFGFHNIKDPDQ 257
Query 316 HSLHGLF--NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSN 373
++ GL +VR+L+L F ++ F+ LK L+ LN+ N I I
Sbjct 258 NTFAGLARSSVRHLDLSHGFVF---------SLNSRVFETLKDLKVLNLAYNKINKIADE 308
Query 374 MFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHL 433
F GL NL+ L+L S+ L L + F L + ++L KN I+ I+ F +L L
Sbjct 309 AFYGLDNLQVLNL--SYNLLGELYSSNFYGLPK--VAYIDLQKNHIAIIQDQTFKFLEKL 364
Query 434 EVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALK 493
+ LDL N + + +I +I+LS NK + L + L +L L R L+
Sbjct 365 QTLDLRDNAL------TTIHFIPSIPDIFLSGNKLVTLPK--INLTANLIHLSENR--LE 414
Query 494 NVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE-KLEILDLQHNNLARLWKHANPG 552
N+D + + +L IL L+ N ++ + D LE L L N L W+
Sbjct 415 NLDILYFLLR-VPHLQILILNQNRFSSCSGDQTPSENPSLEQLFLGENMLQLAWETELCW 473
Query 553 GPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL-----NTLPASVFN 607
+GLSHL +L L N + +P VF L L+ + L N L N LPA
Sbjct 474 D---VFEGLSHLQVLYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHNDLPA---- 526
Query 608 NQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTN 667
+L+ L++ +N + + V F +L+ LD+ N F C CE ++ F+NW+N T+
Sbjct 527 ---NLEILDISRNQLLAPNPDV----FVSLSVLDITHNKFICECE-LSTFINWLNHTNVT 578
Query 668 IPELSSHYLCNTPPHYHGFPVRLFDTSSC-----KDSAPFELFFMINTSILLIFIFIVLL 722
I + C P + G + T C F LF + ++ L + I+ +
Sbjct 579 IAGPPADIYCVYPDSFSGVSLFSLSTEGCXXXXXXXXXXFSLFIVCTVTLTLFLMTILTV 638
Query 723 IHFE 726
F
Sbjct 639 TKFR 642
Score = 60.8 bits (146), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 81/306 (26%), Positives = 137/306 (45%), Gaps = 33/306 (11%)
Query 17 FGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQ 76
F L SS +SH + ++ + DL VLNL +N++ ++ F
Sbjct 260 FAGLARSSVRHLDLSHGFVFSLNSRVFETLKDL----KVLNLAYNKINKIADEAFYGLDN 315
Query 77 LTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ 136
L L++ +N + +L LP + ++LQ N ++ + D+TF F L L L N++
Sbjct 316 LQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALT 375
Query 137 KIKNNP-----FVKQKNLITLD----------LSHNGLSSTK-LGTQVQLENLQELLLSN 180
I P F+ L+TL LS N L + L +++ +LQ L+L+
Sbjct 376 TIHFIPSIPDIFLSGNKLVTLPKINLTANLIHLSENRLENLDILYFLLRVPHLQILILNQ 435
Query 181 NKIQALKSEELDIFANSSLKKLELSSNQIK-----EFSPGCFHAIGRLFGLFLNNVQLGP 235
N+ + ++ N SL++L L N ++ E F + L L+LN+ L
Sbjct 436 NRFSSCSGDQTPS-ENPSLEQLFLGENMLQLAWETELCWDVFEGLSHLQVLYLNHNYLN- 493
Query 236 SLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
SL + L T++R LSL++++L+ S+ NL +LD+S N L D F
Sbjct 494 SLPPGVFSHL--TALRGLSLNSNRLTVLSHNDLPA----NLEILDISRNQLLAPNPDVFV 547
Query 296 WLPQLE 301
L L+
Sbjct 548 SLSVLD 553
>5zsl_A B Toll-like receptor 7
Length=823
Score = 102 bits (254), Expect = 8e-21, Method: Compositional matrix adjust.
Identities = 188/717 (26%), Positives = 280/717 (39%), Gaps = 118/717 (16%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGP--SLTEKLCLELANTS 249
N L+ S N + FS I R+ G L + QL P +L L+L
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNF 386
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
I+ +LS + ++ L ++DLS N ++
Sbjct 387 IKIANLS------------MFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXX 434
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
Q L L+ RY RS + K + L++ N I
Sbjct 435 PQ-----VLEQLYYFRYDKYARSCRFKXXXXXXX----XXXXSCYKYGQTLDLSKNSIFF 485
Query 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
IKS+ F L LK L+LS + S +TL F LA L L+ + N++ + S AF
Sbjct 486 IKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNNRLDLLHSTAFEE 542
Query 430 LGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRR 489
L LEVLD+ N + E I + L++ K L++ LQ+LM+
Sbjct 543 LRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV----------LQKLMMND 583
Query 490 VALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
+ + S + LR L LD+ + N + + L KLE LD+ N+L+ L
Sbjct 584 NDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFL 643
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASV 605
G P +L L+L NG E + L L+ +DL N L T+P +
Sbjct 644 PSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERL 696
Query 606 FNNQVSLKSLNLQKNLITSVEKKVFGPAFR-------------------------NLTEL 640
N SLK+L L+ N I S+ K AF+ NL L
Sbjct 697 SNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKML 756
Query 641 DMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSCK 697
+ N F CTC+++ WFV W+ T IP L++ C P + G V D +C+
Sbjct 757 LLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTCE 812
Score = 64.7 bits (156), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 280/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW---------------RGLENI 458
L N I F L+V+DL +N+I + LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXPQVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRFKXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsm_B A Toll-like receptor 7
Length=823
Score = 102 bits (253), Expect = 9e-21, Method: Compositional matrix adjust.
Identities = 188/717 (26%), Positives = 279/717 (39%), Gaps = 118/717 (16%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGP--SLTEKLCLELANTS 249
N L+ S N + FS I R+ G L + QL P +L L+L
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNF 386
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
I+ +LS + ++ L ++DLS N ++
Sbjct 387 IKIANLS------------MFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXX 434
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
Q L L+ RY RS K + L++ N I
Sbjct 435 XQ-----VLEQLYYFRYDKYARSCRXXXXXXXXXXX----XXSCYKYGQTLDLSKNSIFF 485
Query 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
IKS+ F L LK L+LS + S +TL F LA L L+ + N++ + S AF
Sbjct 486 IKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNNRLDLLHSTAFEE 542
Query 430 LGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRR 489
L LEVLD+ N + E I + L++ K L++ LQ+LM+
Sbjct 543 LRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV----------LQKLMMND 583
Query 490 VALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
+ + S + LR L LD+ + N + + L KLE LD+ N+L+ L
Sbjct 584 NDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFL 643
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASV 605
G P +L L+L NG E + L L+ +DL N L T+P +
Sbjct 644 PSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERL 696
Query 606 FNNQVSLKSLNLQKNLITSVEKKVFGPAFR-------------------------NLTEL 640
N SLK+L L+ N I S+ K AF+ NL L
Sbjct 697 SNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKML 756
Query 641 DMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSCK 697
+ N F CTC+++ WFV W+ T IP L++ C P + G V D +C+
Sbjct 757 LLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTCE 812
Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 280/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIG---------------QELTGQEWRGLENI 458
L N I F L+V+DL +N+I + LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXQVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>3wpf_A A Toll-like receptor 9
Length=803
Score = 101 bits (251), Expect = 1e-20, Method: Compositional matrix adjust.
Identities = 188/794 (24%), Positives = 303/794 (38%), Gaps = 152/794 (19%)
Query 32 HEVADCSHLKLTQVPDDLP----TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
H + DC+ L L VP +NIT L+L N++ L ++F S L L++ +N
Sbjct 19 HGLVDCNWLFLKSVPRFXXXASCSNITRLSLISNRIHHLHNSDFVHLSNLRQLNLKWNCP 78
Query 88 SK------------LEPELCQKLPMLKVLNLQHNELSQ--------------------LS 115
+EP + L+ LNL +N ++ L
Sbjct 79 PTGLSXXXXSCHMTIEPRTFLAMRTLEELNLSYNGITTVPRLPSSLVNLSLSHTNILVLD 138
Query 116 DKTFAFCTNLTELHLMSNSIQK------IKNNP--FVKQKNLITLDLSHNGLSSTKLGTQ 167
+ A +L L + N K +K P + L L L +N L TK+ Q
Sbjct 139 ANSLAGLYSLRVLFMDGNCYYKNPCTGAVKVTPGALLGLSQLTHLSLKYNNL--TKVPRQ 196
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF 227
+ +L+ LL+S N I L E+L +SL+ L++ N + C HA
Sbjct 197 LP-PSLEYLLVSYNLIVKLGPEDLAQL--TSLRVLDVGGNCRR-----CDHAPNPCIECG 248
Query 228 LNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL- 286
++ L P L + + L L +S L T +++ F GL L++LDLS N L
Sbjct 249 QKSLHLHPETFHHL------SHLEGLVLKDSSLHTLNSSWFQGL--VQLSVLDLSENFLY 300
Query 287 -NVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH------GLFNVRYLNLK----RSFTK 335
++ ++F L +L L +N + + LH L +++ LN+ R K
Sbjct 301 ESITHTNAFQNLTRLRKLNLSFNYRKKVSFARLHLASSFKNLVSLQELNMNGIFFRLLNK 360
Query 336 QSIS-LASLPKIDDFSFQW-------------LKCLEHLNMEDNDIPGIKSNMFTGLINL 381
++ LA LPK+ Q + L +++ DN I G +
Sbjct 361 YTLRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRISGPSTXXXXXXXXX 420
Query 382 KYLSLSNSFTSLRTLTNET------FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEV 435
F+ + ++L++N + I+ + F L L+
Sbjct 421 XXXXXXXXXXXXXXXXXXXXXXXXNFMDRCKNFKFTMDLSRNNLVTIKPEMFVQLSRLQC 480
Query 436 LDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML----RRVA 491
L L N I Q + G ++ L N+ + LS+NK SF+ +P LQ L L +
Sbjct 481 LSLSHNSIAQAVNGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSQPFX 540
Query 492 LKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANP 551
+ S L L L L++N+I L + LD N + R+W
Sbjct 541 XXGIGHQFSFVTHLSMLQSLSLAHNDIHTRVSSHLNS-NSVRFLDFSGNGMGRMWDEG-- 597
Query 552 GGPIYFLKGLSHLHILNLESNGFDEIPVEVFKD-------------------------LF 586
G ++F +GLS L L+L N + + + L
Sbjct 598 GLYLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLKLLSLRDNYLSFFNWTSLSFLP 657
Query 587 ELKIIDLGLNNL-----NTLP-------------------ASVFNNQVSLKSLNLQKNLI 622
L+++DL N L TLP + F V LK +NL N++
Sbjct 658 NLEVLDLAGNQLKALTQGTLPNGTLLQKLDVSSNSIVSVVPAFFALAVELKEVNLSHNIL 717
Query 623 TSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPH 682
+V++ FGP LT LD+R NP C C A FV+ + E T +P L++ C +P
Sbjct 718 KTVDRSWFGPIVMQLTVLDVRSNPLHCACG--AAFVDLLLEVQTKVPGLANGVKCGSPGQ 775
Query 683 YHGFPVRLFDTSSC 696
G + D C
Sbjct 776 LQGRSIFAQDLRLC 789
>5gmf_A A Toll-like receptor 7
Length=817
Score = 100 bits (250), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 187/716 (26%), Positives = 278/716 (39%), Gaps = 118/716 (16%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGP--SLTEKLCLELANTS 249
N L+ S N + FS I R+ G L + QL P +L L+L
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNF 386
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
I+ +LS + ++ L ++DLS N ++
Sbjct 387 IKIANLS------------MFKQFKRLKVIDLSVNKISPXXXXXXX-----XXXXXXXXX 429
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
L L+ RY RS + K + L++ N I
Sbjct 430 XXXXXXXVLEQLYYFRYDKYARSCRFKXXXXXXXXX----XXSCYKYGQTLDLSKNSIFF 485
Query 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
IKS+ F L LK L+LS + S +TL F LA L L+ + N++ + S AF
Sbjct 486 IKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNNRLDLLHSTAFEE 542
Query 430 LGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRR 489
L LEVLD+ N + E I + L++ K L++ LQ+LM+
Sbjct 543 LRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV----------LQKLMMND 583
Query 490 VALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
+ + S + LR L LD+ + N + + L KLE LD+ N+L+ L
Sbjct 584 NDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFL 643
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASV 605
G P +L L+L NG E + L L+ +DL N L T+P +
Sbjct 644 PSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERL 696
Query 606 FNNQVSLKSLNLQKNLITSVEKKVFGPAFR-------------------------NLTEL 640
N SLK+L L+ N I S+ K AF+ NL L
Sbjct 697 SNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKML 756
Query 641 DMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSC 696
+ N F CTC+++ WFV W+ T IP L++ C P + G V D +C
Sbjct 757 LLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTC 811
Score = 67.4 bits (163), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 173/757 (23%), Positives = 283/757 (37%), Gaps = 175/757 (23%)
Query 11 WGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAAN 70
W P + C T + +H + DC+ LT++P +PTN T L LT N + + A+
Sbjct 4 WARWFPKTLPC-DVTLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPAS 62
Query 71 FTRYSQLTSLDVGFNTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSD 116
F R L +D N + +++P L LK L L N+L ++
Sbjct 63 FHRLVHLVEIDFRCNCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ 122
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQEL 176
+L L L +N+I I+ + N+ L L N +E L
Sbjct 123 ---GLPPSLQLLSLEANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFL 179
Query 177 LLSNNKIQALKSEELDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
L+ K+ +LK + S+L +L L +N I E F+ LN +Q+
Sbjct 180 NLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI 231
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
L+L+ R N F N + L + N +
Sbjct 232 ---------LDLSGNCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------A 263
Query 294 FAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKI 346
F L +L+ L N++QH+ + N++ L+L ++F + I L +L ++
Sbjct 264 FDALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQL 323
Query 347 D-DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLA 405
D F+F+ +N+ S F+ L +LK L +R + S
Sbjct 324 DLSFNFELQVYRASMNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQ 367
Query 406 HSPLH------ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG----- 454
SPLH +L+L N I F L+V+DL +N+I
Sbjct 368 LSPLHNLQNLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXX 427
Query 455 ----------LENIFEIYLSYNKY--------------------------LQLTRNSFAL 478
LE ++ Y Y+KY L L++NS
Sbjct 428 XXXXXXXXXVLEQLY--YFRYDKYARSCRFKXXXXXXXXXXXSCYKYGQTLDLSKNSIFF 485
Query 479 VPSLQRLMLRRVALKNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
+ S L + N+ + S FQPL L LD SNN + ++ E L K
Sbjct 486 IKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRK 545
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF----------------- 574
LE+LD+ N + ++ + F K L L L + N
Sbjct 546 LEVLDISSN--SHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLE 603
Query 575 -------------DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKN 620
D +++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN
Sbjct 604 FRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKN 663
Query 621 LITSV--EKKVFGPAFRNLTELDMRFNPFDCTCESIA 655
+ S EK + +NL LD+ N E ++
Sbjct 664 GLKSFIWEKLRY---LKNLETLDLSHNQLTTVPERLS 697
>5gmf_C C Toll-like receptor 7
Length=817
Score = 100 bits (250), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 187/716 (26%), Positives = 278/716 (39%), Gaps = 118/716 (16%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGP--SLTEKLCLELANTS 249
N L+ S N + FS I R+ G L + QL P +L L+L
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNF 386
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
I+ +LS + ++ L ++DLS N ++
Sbjct 387 IKIANLS------------MFKQFKRLKVIDLSVNKISPXXXXXXX-----XXXXXXXXX 429
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
L L+ RY RS + K + L++ N I
Sbjct 430 XXXXXXXVLEQLYYFRYDKYARSCRFKXXXXXXXXX----XXSCYKYGQTLDLSKNSIFF 485
Query 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
IKS+ F L LK L+LS + S +TL F LA L L+ + N++ + S AF
Sbjct 486 IKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNNRLDLLHSTAFEE 542
Query 430 LGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRR 489
L LEVLD+ N + E I + L++ K L++ LQ+LM+
Sbjct 543 LRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV----------LQKLMMND 583
Query 490 VALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
+ + S + LR L LD+ + N + + L KLE LD+ N+L+ L
Sbjct 584 NDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFL 643
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASV 605
G P +L L+L NG E + L L+ +DL N L T+P +
Sbjct 644 PSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERL 696
Query 606 FNNQVSLKSLNLQKNLITSVEKKVFGPAFR-------------------------NLTEL 640
N SLK+L L+ N I S+ K AF+ NL L
Sbjct 697 SNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKML 756
Query 641 DMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSC 696
+ N F CTC+++ WFV W+ T IP L++ C P + G V D +C
Sbjct 757 LLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTC 811
Score = 67.4 bits (163), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 173/757 (23%), Positives = 283/757 (37%), Gaps = 175/757 (23%)
Query 11 WGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAAN 70
W P + C T + +H + DC+ LT++P +PTN T L LT N + + A+
Sbjct 4 WARWFPKTLPC-DVTLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPAS 62
Query 71 FTRYSQLTSLDVGFNTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSD 116
F R L +D N + +++P L LK L L N+L ++
Sbjct 63 FHRLVHLVEIDFRCNCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ 122
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQEL 176
+L L L +N+I I+ + N+ L L N +E L
Sbjct 123 ---GLPPSLQLLSLEANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFL 179
Query 177 LLSNNKIQALKSEELDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
L+ K+ +LK + S+L +L L +N I E F+ LN +Q+
Sbjct 180 NLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI 231
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
L+L+ R N F N + L + N +
Sbjct 232 ---------LDLSGNCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------A 263
Query 294 FAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKI 346
F L +L+ L N++QH+ + N++ L+L ++F + I L +L ++
Sbjct 264 FDALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQL 323
Query 347 D-DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLA 405
D F+F+ +N+ S F+ L +LK L +R + S
Sbjct 324 DLSFNFELQVYRASMNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQ 367
Query 406 HSPLH------ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG----- 454
SPLH +L+L N I F L+V+DL +N+I
Sbjct 368 LSPLHNLQNLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXX 427
Query 455 ----------LENIFEIYLSYNKY--------------------------LQLTRNSFAL 478
LE ++ Y Y+KY L L++NS
Sbjct 428 XXXXXXXXXVLEQLY--YFRYDKYARSCRFKXXXXXXXXXXXSCYKYGQTLDLSKNSIFF 485
Query 479 VPSLQRLMLRRVALKNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
+ S L + N+ + S FQPL L LD SNN + ++ E L K
Sbjct 486 IKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRK 545
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF----------------- 574
LE+LD+ N + ++ + F K L L L + N
Sbjct 546 LEVLDISSN--SHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLE 603
Query 575 -------------DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKN 620
D +++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN
Sbjct 604 FRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKN 663
Query 621 LITSV--EKKVFGPAFRNLTELDMRFNPFDCTCESIA 655
+ S EK + +NL LD+ N E ++
Sbjct 664 GLKSFIWEKLRY---LKNLETLDLSHNQLTTVPERLS 697
>5gmf_D D Toll-like receptor 7
Length=817
Score = 100 bits (250), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 187/716 (26%), Positives = 278/716 (39%), Gaps = 118/716 (16%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGP--SLTEKLCLELANTS 249
N L+ S N + FS I R+ G L + QL P +L L+L
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNF 386
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
I+ +LS + ++ L ++DLS N ++
Sbjct 387 IKIANLS------------MFKQFKRLKVIDLSVNKISPXXXXXXX-----XXXXXXXXX 429
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
L L+ RY RS + K + L++ N I
Sbjct 430 XXXXXXXVLEQLYYFRYDKYARSCRFKXXXXXXXXX----XXSCYKYGQTLDLSKNSIFF 485
Query 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
IKS+ F L LK L+LS + S +TL F LA L L+ + N++ + S AF
Sbjct 486 IKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNNRLDLLHSTAFEE 542
Query 430 LGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRR 489
L LEVLD+ N + E I + L++ K L++ LQ+LM+
Sbjct 543 LRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV----------LQKLMMND 583
Query 490 VALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
+ + S + LR L LD+ + N + + L KLE LD+ N+L+ L
Sbjct 584 NDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFL 643
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASV 605
G P +L L+L NG E + L L+ +DL N L T+P +
Sbjct 644 PSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERL 696
Query 606 FNNQVSLKSLNLQKNLITSVEKKVFGPAFR-------------------------NLTEL 640
N SLK+L L+ N I S+ K AF+ NL L
Sbjct 697 SNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKML 756
Query 641 DMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSC 696
+ N F CTC+++ WFV W+ T IP L++ C P + G V D +C
Sbjct 757 LLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTC 811
Score = 67.4 bits (163), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 173/757 (23%), Positives = 283/757 (37%), Gaps = 175/757 (23%)
Query 11 WGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAAN 70
W P + C T + +H + DC+ LT++P +PTN T L LT N + + A+
Sbjct 4 WARWFPKTLPC-DVTLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPAS 62
Query 71 FTRYSQLTSLDVGFNTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSD 116
F R L +D N + +++P L LK L L N+L ++
Sbjct 63 FHRLVHLVEIDFRCNCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ 122
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQEL 176
+L L L +N+I I+ + N+ L L N +E L
Sbjct 123 ---GLPPSLQLLSLEANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFL 179
Query 177 LLSNNKIQALKSEELDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
L+ K+ +LK + S+L +L L +N I E F+ LN +Q+
Sbjct 180 NLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI 231
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
L+L+ R N F N + L + N +
Sbjct 232 ---------LDLSGNCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------A 263
Query 294 FAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKI 346
F L +L+ L N++QH+ + N++ L+L ++F + I L +L ++
Sbjct 264 FDALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQL 323
Query 347 D-DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLA 405
D F+F+ +N+ S F+ L +LK L +R + S
Sbjct 324 DLSFNFELQVYRASMNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQ 367
Query 406 HSPLH------ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG----- 454
SPLH +L+L N I F L+V+DL +N+I
Sbjct 368 LSPLHNLQNLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXX 427
Query 455 ----------LENIFEIYLSYNKY--------------------------LQLTRNSFAL 478
LE ++ Y Y+KY L L++NS
Sbjct 428 XXXXXXXXXVLEQLY--YFRYDKYARSCRFKXXXXXXXXXXXSCYKYGQTLDLSKNSIFF 485
Query 479 VPSLQRLMLRRVALKNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
+ S L + N+ + S FQPL L LD SNN + ++ E L K
Sbjct 486 IKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRK 545
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF----------------- 574
LE+LD+ N + ++ + F K L L L + N
Sbjct 546 LEVLDISSN--SHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLE 603
Query 575 -------------DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKN 620
D +++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN
Sbjct 604 FRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKN 663
Query 621 LITSV--EKKVFGPAFRNLTELDMRFNPFDCTCESIA 655
+ S EK + +NL LD+ N E ++
Sbjct 664 GLKSFIWEKLRY---LKNLETLDLSHNQLTTVPERLS 697
>5gmf_B B Toll-like receptor 7
Length=817
Score = 100 bits (250), Expect = 2e-20, Method: Compositional matrix adjust.
Identities = 187/716 (26%), Positives = 278/716 (39%), Gaps = 118/716 (16%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGP--SLTEKLCLELANTS 249
N L+ S N + FS I R+ G L + QL P +L L+L
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNF 386
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
I+ +LS + ++ L ++DLS N ++
Sbjct 387 IKIANLS------------MFKQFKRLKVIDLSVNKISPXXXXXXX-----XXXXXXXXX 429
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
L L+ RY RS + K + L++ N I
Sbjct 430 XXXXXXXVLEQLYYFRYDKYARSCRFKXXXXXXXXX----XXSCYKYGQTLDLSKNSIFF 485
Query 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
IKS+ F L LK L+LS + S +TL F LA L L+ + N++ + S AF
Sbjct 486 IKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNNRLDLLHSTAFEE 542
Query 430 LGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRR 489
L LEVLD+ N + E I + L++ K L++ LQ+LM+
Sbjct 543 LRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV----------LQKLMMND 583
Query 490 VALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
+ + S + LR L LD+ + N + + L KLE LD+ N+L+ L
Sbjct 584 NDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFL 643
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASV 605
G P +L L+L NG E + L L+ +DL N L T+P +
Sbjct 644 PSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERL 696
Query 606 FNNQVSLKSLNLQKNLITSVEKKVFGPAFR-------------------------NLTEL 640
N SLK+L L+ N I S+ K AF+ NL L
Sbjct 697 SNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKML 756
Query 641 DMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSC 696
+ N F CTC+++ WFV W+ T IP L++ C P + G V D +C
Sbjct 757 LLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSVISLDLYTC 811
Score = 67.4 bits (163), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 173/757 (23%), Positives = 283/757 (37%), Gaps = 175/757 (23%)
Query 11 WGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAAN 70
W P + C T + +H + DC+ LT++P +PTN T L LT N + + A+
Sbjct 4 WARWFPKTLPC-DVTLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPAS 62
Query 71 FTRYSQLTSLDVGFNTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSD 116
F R L +D N + +++P L LK L L N+L ++
Sbjct 63 FHRLVHLVEIDFRCNCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ 122
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQEL 176
+L L L +N+I I+ + N+ L L N +E L
Sbjct 123 ---GLPPSLQLLSLEANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFL 179
Query 177 LLSNNKIQALKSEELDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
L+ K+ +LK + S+L +L L +N I E F+ LN +Q+
Sbjct 180 NLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI 231
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
L+L+ R N F N + L + N +
Sbjct 232 ---------LDLSGNCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------A 263
Query 294 FAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKI 346
F L +L+ L N++QH+ + N++ L+L ++F + I L +L ++
Sbjct 264 FDALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQL 323
Query 347 D-DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLA 405
D F+F+ +N+ S F+ L +LK L +R + S
Sbjct 324 DLSFNFELQVYRASMNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQ 367
Query 406 HSPLH------ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG----- 454
SPLH +L+L N I F L+V+DL +N+I
Sbjct 368 LSPLHNLQNLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXX 427
Query 455 ----------LENIFEIYLSYNKY--------------------------LQLTRNSFAL 478
LE ++ Y Y+KY L L++NS
Sbjct 428 XXXXXXXXXVLEQLY--YFRYDKYARSCRFKXXXXXXXXXXXSCYKYGQTLDLSKNSIFF 485
Query 479 VPSLQRLMLRRVALKNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
+ S L + N+ + S FQPL L LD SNN + ++ E L K
Sbjct 486 IKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRK 545
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF----------------- 574
LE+LD+ N + ++ + F K L L L + N
Sbjct 546 LEVLDISSN--SHYFQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLE 603
Query 575 -------------DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKN 620
D +++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN
Sbjct 604 FRGNHLDVLWRDGDNRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKN 663
Query 621 LITSV--EKKVFGPAFRNLTELDMRFNPFDCTCESIA 655
+ S EK + +NL LD+ N E ++
Sbjct 664 GLKSFIWEKLRY---LKNLETLDLSHNQLTTVPERLS 697
>6lvx_B B Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 169/737 (23%), Positives = 277/737 (38%), Gaps = 174/737 (24%)
Query 31 SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS-- 88
+H + DC+ LT++P +PTN T L LT N + + A+F R L +D N +
Sbjct 23 NHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRCNCVPIR 82
Query 89 ------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ 136
+++P L LK L L N+L ++ +L L L +N+I
Sbjct 83 LGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSLEANNIF 139
Query 137 KIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN 196
I+ + N+ L L N +E L L+ K+ +LK +
Sbjct 140 SIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPT 199
Query 197 ---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNL 253
S+L +L L +N I E F+ LN +Q+ L+L+ R
Sbjct 200 VLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSGNCPR-- 240
Query 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
N F N + L + N +F L +L+ L N++QH+
Sbjct 241 ---------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHSNSLQHV 283
Query 314 FSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEHLNMEDN 365
+ N++ L+L ++F + I L +L ++D F+F+ +N+
Sbjct 284 PPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRASMNL--- 340
Query 366 DIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILNLTKNKI 419
S F+ L +LK L +R + S SPLH +L+L N I
Sbjct 341 ------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNFI 387
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENIFEIYLS 464
F L+V+DL +N+I LE ++ Y
Sbjct 388 KIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQLY--YFR 445
Query 465 YNKY--------------------------LQLTRNSFALVPSLQRLMLRRVALKNVDS- 497
Y+KY L L++NS + S L + N+
Sbjct 446 YDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGN 505
Query 498 ------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANP 551
+ S FQPL L LD SNN + ++ E L KLE+LD+ N + ++
Sbjct 506 LISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHYFQSEGI 563
Query 552 GGPIYFLKGLSHLHILNLESNGF------------------------------DEIPVEV 581
+ F K L L L + N D +++
Sbjct 564 THMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQL 623
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGPAFRNLT 638
FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK + +NL
Sbjct 624 FKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY---LKNLE 680
Query 639 ELDMRFNPFDCTCESIA 655
LD+ N E ++
Sbjct 681 TLDLSHNQLTTVPERLS 697
>6lvy_B B Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 169/737 (23%), Positives = 277/737 (38%), Gaps = 174/737 (24%)
Query 31 SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS-- 88
+H + DC+ LT++P +PTN T L LT N + + A+F R L +D N +
Sbjct 23 NHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRCNCVPIR 82
Query 89 ------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ 136
+++P L LK L L N+L ++ +L L L +N+I
Sbjct 83 LGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSLEANNIF 139
Query 137 KIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN 196
I+ + N+ L L N +E L L+ K+ +LK +
Sbjct 140 SIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPT 199
Query 197 ---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNL 253
S+L +L L +N I E F+ LN +Q+ L+L+ R
Sbjct 200 VLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSGNCPR-- 240
Query 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
N F N + L + N +F L +L+ L N++QH+
Sbjct 241 ---------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHSNSLQHV 283
Query 314 FSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEHLNMEDN 365
+ N++ L+L ++F + I L +L ++D F+F+ +N+
Sbjct 284 PPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRASMNL--- 340
Query 366 DIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILNLTKNKI 419
S F+ L +LK L +R + S SPLH +L+L N I
Sbjct 341 ------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNFI 387
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENIFEIYLS 464
F L+V+DL +N+I LE ++ Y
Sbjct 388 KIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQLY--YFR 445
Query 465 YNKY--------------------------LQLTRNSFALVPSLQRLMLRRVALKNVDS- 497
Y+KY L L++NS + S L + N+
Sbjct 446 YDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGN 505
Query 498 ------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANP 551
+ S FQPL L LD SNN + ++ E L KLE+LD+ N + ++
Sbjct 506 LISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHYFQSEGI 563
Query 552 GGPIYFLKGLSHLHILNLESNGF------------------------------DEIPVEV 581
+ F K L L L + N D +++
Sbjct 564 THMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQL 623
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGPAFRNLT 638
FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK + +NL
Sbjct 624 FKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY---LKNLE 680
Query 639 ELDMRFNPFDCTCESIA 655
LD+ N E ++
Sbjct 681 TLDLSHNQLTTVPERLS 697
>6lvx_A A Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 169/737 (23%), Positives = 277/737 (38%), Gaps = 174/737 (24%)
Query 31 SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS-- 88
+H + DC+ LT++P +PTN T L LT N + + A+F R L +D N +
Sbjct 23 NHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRCNCVPIR 82
Query 89 ------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ 136
+++P L LK L L N+L ++ +L L L +N+I
Sbjct 83 LGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSLEANNIF 139
Query 137 KIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN 196
I+ + N+ L L N +E L L+ K+ +LK +
Sbjct 140 SIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPT 199
Query 197 ---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNL 253
S+L +L L +N I E F+ LN +Q+ L+L+ R
Sbjct 200 VLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSGNCPR-- 240
Query 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
N F N + L + N +F L +L+ L N++QH+
Sbjct 241 ---------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHSNSLQHV 283
Query 314 FSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEHLNMEDN 365
+ N++ L+L ++F + I L +L ++D F+F+ +N+
Sbjct 284 PPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRASMNL--- 340
Query 366 DIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILNLTKNKI 419
S F+ L +LK L +R + S SPLH +L+L N I
Sbjct 341 ------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNFI 387
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENIFEIYLS 464
F L+V+DL +N+I LE ++ Y
Sbjct 388 KIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQLY--YFR 445
Query 465 YNKY--------------------------LQLTRNSFALVPSLQRLMLRRVALKNVDS- 497
Y+KY L L++NS + S L + N+
Sbjct 446 YDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGN 505
Query 498 ------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANP 551
+ S FQPL L LD SNN + ++ E L KLE+LD+ N + ++
Sbjct 506 LISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHYFQSEGI 563
Query 552 GGPIYFLKGLSHLHILNLESNGF------------------------------DEIPVEV 581
+ F K L L L + N D +++
Sbjct 564 THMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQL 623
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGPAFRNLT 638
FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK + +NL
Sbjct 624 FKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY---LKNLE 680
Query 639 ELDMRFNPFDCTCESIA 655
LD+ N E ++
Sbjct 681 TLDLSHNQLTTVPERLS 697
>6lvy_A A Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.2 bits (152), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 169/737 (23%), Positives = 277/737 (38%), Gaps = 174/737 (24%)
Query 31 SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS-- 88
+H + DC+ LT++P +PTN T L LT N + + A+F R L +D N +
Sbjct 23 NHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRCNCVPIR 82
Query 89 ------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ 136
+++P L LK L L N+L ++ +L L L +N+I
Sbjct 83 LGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSLEANNIF 139
Query 137 KIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN 196
I+ + N+ L L N +E L L+ K+ +LK +
Sbjct 140 SIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPT 199
Query 197 ---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNL 253
S+L +L L +N I E F+ LN +Q+ L+L+ R
Sbjct 200 VLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSGNCPR-- 240
Query 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
N F N + L + N +F L +L+ L N++QH+
Sbjct 241 ---------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHSNSLQHV 283
Query 314 FSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEHLNMEDN 365
+ N++ L+L ++F + I L +L ++D F+F+ +N+
Sbjct 284 PPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRASMNL--- 340
Query 366 DIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILNLTKNKI 419
S F+ L +LK L +R + S SPLH +L+L N I
Sbjct 341 ------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNFI 387
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENIFEIYLS 464
F L+V+DL +N+I LE ++ Y
Sbjct 388 KIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQLY--YFR 445
Query 465 YNKY--------------------------LQLTRNSFALVPSLQRLMLRRVALKNVDS- 497
Y+KY L L++NS + S L + N+
Sbjct 446 YDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGN 505
Query 498 ------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANP 551
+ S FQPL L LD SNN + ++ E L KLE+LD+ N + ++
Sbjct 506 LISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHYFQSEGI 563
Query 552 GGPIYFLKGLSHLHILNLESNGF------------------------------DEIPVEV 581
+ F K L L L + N D +++
Sbjct 564 THMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQL 623
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGPAFRNLT 638
FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK + +NL
Sbjct 624 FKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY---LKNLE 680
Query 639 ELDMRFNPFDCTCESIA 655
LD+ N E ++
Sbjct 681 TLDLSHNQLTTVPERLS 697
>5gmh_B B Toll-like receptor 7
Length=817
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>8ttz_A A Toll-like receptor 7
Length=817
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>8ttz_B B Toll-like receptor 7
Length=817
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5gmh_A A Toll-like receptor 7
Length=817
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsi_B A Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsj_B B Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsj_A A Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsi_A B Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsf_A B Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsn_B A Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsn_A B Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsh_A B Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsh_B A Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsg_B A Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsg_A B Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>6lw0_A B Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>6lvz_B A Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>6lvz_A B Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>6lw0_B A Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsf_B A Toll-like receptor 7
Length=823
Score = 100 bits (249), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCXXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsb_B A Toll-like receptor 7
Length=823
Score = 100 bits (248), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.5 bits (153), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsd_B A Toll-like receptor 7
Length=823
Score = 100 bits (248), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.5 bits (153), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>6if5_A B Toll-like receptor 7
Length=823
Score = 100 bits (248), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.5 bits (153), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsl_B A Toll-like receptor 7
Length=823
Score = 100 bits (248), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.5 bits (153), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsa_B A Toll-like receptor 7
Length=823
Score = 100 bits (248), Expect = 3e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRXXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.5 bits (153), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsc_A B Toll-like receptor 7
Length=823
Score = 100 bits (248), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 276/734 (38%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS +
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRFKXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRFKXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zse_A B Toll-like receptor 7
Length=823
Score = 100 bits (248), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 276/734 (38%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS +
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRFKXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRFKXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsa_A B Toll-like receptor 7
Length=823
Score = 100 bits (248), Expect = 4e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 276/734 (38%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS +
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRFKXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRFKXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>6if5_B A Toll-like receptor 7
Length=823
Score = 99.4 bits (246), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRFXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRFXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsb_A B Toll-like receptor 7
Length=823
Score = 99.4 bits (246), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRFXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRFXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zse_B A Toll-like receptor 7
Length=823
Score = 99.4 bits (246), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRFXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRFXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsd_A B Toll-like receptor 7
Length=823
Score = 99.4 bits (246), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRFXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRFXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>5zsc_B A Toll-like receptor 7
Length=823
Score = 99.4 bits (246), Expect = 6e-20, Method: Compositional matrix adjust.
Identities = 190/734 (26%), Positives = 275/734 (37%), Gaps = 152/734 (21%)
Query 28 CTVSHEVADCSHLKLTQ-------------VPDDLPTNITVLNLTHNQLRRLPAANFTRY 74
C VS+ + + L LT+ VP LP+ +T L L +N + + +F
Sbjct 167 CYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELYLYNNMIAEIQEDDFNNL 226
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
+QL LD+ N P C P ++N Q+ F T L L L SNS
Sbjct 227 NQLQILDLSGNC-----PR-CYNAP-FPCTPCKNNSPLQIPVNAFDALTELKVLRLHSNS 279
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+Q + F NL LDLS N L+ ++G L L L+ +LD+
Sbjct 280 LQHVPPRWFKNINNLQELDLSQNFLAK-EIGDAKFLHFLPNLI------------QLDLS 326
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF---LNNVQLGPSLTEKLCLELANTSIR 251
N L+ S N + FS I R+ G L + QL P
Sbjct 327 FNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSP---------------- 370
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L N Q NL +LDL N + + F +L+ L N I
Sbjct 371 ---LHNLQ---------------NLEVLDLGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Query 312 HLFSHS-------------------LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L L+ RY RS
Sbjct 413 PXXXXXXXXXXXXXXXXXXXXXXXVLEQLYYFRYDKYARSCRFXXXXXXXXXX----XXS 468
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHIL 412
K + L++ N I IKS+ F L LK L+LS + S +TL F LA L L
Sbjct 469 CYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYL 525
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+ + N++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 526 DFSNNRLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV- 575
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEG 528
LQ+LM+ + + S + LR L LD+ + N + +
Sbjct 576 ---------LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L KLE LD+ N+L+ L G P +L L+L NG E + L L
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNL 679
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------- 635
+ +DL N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 680 ETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQM 739
Query 636 ------------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
NL L + N F CTC+++ WFV W+ T IP L++ C P +
Sbjct 740 IQKTSFPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAH 798
Query 684 HGFPVRLFDTSSCK 697
G V D +C+
Sbjct 799 KGQSVISLDLYTCE 812
Score = 63.9 bits (154), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 170/743 (23%), Positives = 279/743 (38%), Gaps = 174/743 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG---------------LENI 458
L N I F L+V+DL +N+I LE +
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXVLEQL 441
Query 459 FEIYLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVAL 492
+ Y Y+KY L L++NS + S L +
Sbjct 442 Y--YFRYDKYARSCRFXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKC 499
Query 493 KNVDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
N+ + S FQPL L LD SNN + ++ E L KLE+LD+ N +
Sbjct 500 LNLSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHY 557
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGF------------------------------D 575
++ + F K L L L + N D
Sbjct 558 FQSEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGD 617
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGP 632
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 618 NRYLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY-- 675
Query 633 AFRNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 676 -LKNLETLDLSHNQLTTVPERLS 697
>2z63_A A Toll-like receptor 4, Variable lymphocyte receptor B
Length=570
Score = 98.2 bits (243), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 162/638 (25%), Positives = 267/638 (42%), Gaps = 116/638 (18%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 14 CMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 73
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 74 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 133
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFAN--SSLKKLELSSNQIKEFS 213
N + S KL L NL+ L LS+NKIQ++ +L + L+LS N +
Sbjct 134 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 193
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
PG F I RL L L N K C++ LA + L L L +
Sbjct 194 PGAFKEI-RLHKLTLRN-NFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSAL 251
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
GL NLT+ + L L+Y+ ++I LF + L NV
Sbjct 252 EGL--CNLTIEEFR--------------LAYLDYYL---DDIIDLF----NCLTNV---- 284
Query 329 LKRSFTKQSISLASLPKIDDFS--FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
SF+ S+++ ++ DFS F W + LE +N + P +K
Sbjct 285 --SSFSLVSVTIE---RVKDFSYNFGW-QHLELVNCKFGQFPTLK--------------- 323
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG-Q 445
L++L TF S N N S+++ L LE LDL N + +
Sbjct 324 ------LKSLKRLTFTS---------NKGGNAFSEVD------LPSLEFLDLSRNGLSFK 362
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
Q G ++ + LS+N + ++ N F + L+ L + LK + S S F L
Sbjct 363 GCCSQSDFGTTSLKYLDLSFNGVITMSSN-FLGLEQLEHLDFQHSNLKQM-SEFSVFLSL 420
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
RNL LD+S+ + + + GL LE+L + N+ + P F + L +L
Sbjct 421 RNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFL------PDIFTE-LRNLT 473
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L +++ F L L+++++ N L ++P +F+ SL+ + L
Sbjct 474 FLDLSQCQLEQLSPTAFNSLSSLQVLNMASNQLKSVPDGIFDRLTSLQKIWLHT------ 527
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
NP+DC+C I + W+N+
Sbjct 528 -------------------NPWDCSCPRIDYLSRWLNK 546
>3wpi_A A Toll-like receptor 9
Length=803
Score = 98.6 bits (244), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 187/794 (24%), Positives = 299/794 (38%), Gaps = 152/794 (19%)
Query 32 HEVADCSHLKLTQVPDDLP----TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
H + DC+ L L VP +NIT L+L N++ L ++F S L L++ +N
Sbjct 19 HGLVDCNWLFLKSVPRFXXXXSCSNITRLSLISNRIHHLHNSDFVHLSNLRQLNLKWNCP 78
Query 88 SK------------LEPELCQKLPMLKVLNLQHNELSQ--------------------LS 115
+EP + L+ LNL +N ++ L
Sbjct 79 PTGLSXXXXSCHMTIEPRTFLAMRTLEELNLSYNGITTVPRLPSSLVNLSLSHTNILVLD 138
Query 116 DKTFAFCTNLTELHLMSNSIQK------IKNNP--FVKQKNLITLDLSHNGLSSTKLGTQ 167
+ A +L L + N K +K P + L L L +N L TK+ Q
Sbjct 139 ANSLAGLYSLRVLFMDGNCYYKNPCTGAVKVTPGALLGLSQLTHLSLKYNNL--TKVPRQ 196
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF 227
+ +L+ LL+S N I L E+L +SL+ L++ N + C HA
Sbjct 197 LP-PSLEYLLVSYNLIVKLGPEDLAQL--TSLRVLDVGGNCRR-----CDHAPNPCIECG 248
Query 228 LNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL- 286
++ L P L + + L L +S L T +++ F GL L++LDLS N L
Sbjct 249 QKSLHLHPETFHHL------SHLEGLVLKDSSLHTLNSSWFQGL--VQLSVLDLSENFLY 300
Query 287 -NVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH------GLFNVRYLNLK----RSFTK 335
++ ++F L +L L +N LH L +++ LN+ R K
Sbjct 301 ESITHTNAFQNLTRLRKLNLSFNYRXXXXXXRLHLASSFKNLVSLQELNMNGIFFRLLNK 360
Query 336 QSIS-LASLPKIDDFSFQW-------------LKCLEHLNMEDNDIPGIKSNMFTGLINL 381
++ LA LPK+ Q + L +++ DN I G +
Sbjct 361 YTLRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRISGPSTXXXXXXXXX 420
Query 382 KYLSLSNSFTSLRTLTNETF------VSLAHSPLHILNLTKNKISKIESDAFSWLGHLEV 435
+ ++L++N + I+ + F L L+
Sbjct 421 XXXXXXXXXXXXXXXXXXXXXXXXXXMDRCKXXKFTMDLSRNNLVTIKPEMFVQLSRLQC 480
Query 436 LDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML----RRVA 491
L L N I Q + G ++ L N+ + LS+NK SF+ +P LQ L L +
Sbjct 481 LSLSHNSIAQAVNGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSQXXX 540
Query 492 LKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANP 551
+ S L L L L++N+I L + LD N + R+W
Sbjct 541 XXGIGHQFSFVTHLSMLQSLSLAHNDIHTRVSSHLNS-NSVRFLDFSGNGMGRMWDEG-- 597
Query 552 GGPIYFLKGLSHLHILNLESNGFDEIPVEVFKD-------------------------LF 586
G ++F +GLS L L+L N + + + L
Sbjct 598 GLYLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLKLLSLRDNYLSFFNWTSLSFLP 657
Query 587 ELKIIDLGLNNL-----NTLP-------------------ASVFNNQVSLKSLNLQKNLI 622
L+++DL N L TLP + F V LK +NL N++
Sbjct 658 NLEVLDLAGNQLKALTQGTLPNGTLLQKLDVSSNSIVSVVPAFFALAVELKEVNLSHNIL 717
Query 623 TSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPH 682
+V++ FGP LT LD+R NP C C A FV+ + E T +P L++ C +P
Sbjct 718 KTVDRSWFGPIVMQLTVLDVRSNPLHCACG--AAFVDLLLEVQTKVPGLANGVKCGSPGQ 775
Query 683 YHGFPVRLFDTSSC 696
G + D C
Sbjct 776 LQGRSIFAQDLRLC 789
>4qxe_A A Leucine-rich repeat-containing G-protein coupled receptor
4, linker, Variable lymphocyte receptor B
Length=443
Score = 94.4 bits (233), Expect = 6e-19, Method: Compositional matrix adjust.
Identities = 110/385 (29%), Positives = 168/385 (44%), Gaps = 30/385 (8%)
Query 20 LCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTS 79
LCA+ + C V DCS LT VP+ L L+++ N + +LP F + L
Sbjct 4 LCAAPCS-CDGDRRV-DCSGKGLTAVPEGLSAFTQALDISMNNITQLPEGAFKNFPFLEE 61
Query 80 LDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
L + N +S + P+ L LKVL LQ+N+L + + + L L L +N I +
Sbjct 62 LQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVP 121
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SS 198
+ F L L L N L+ + L LQ L L+ NKI ++ F N SS
Sbjct 122 EDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFA---FTNLSS 178
Query 199 LKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLG--PSLTEKLCLELANTSIRNLSLS 256
L L L +N+I+ S CF + L L LN LG P + L S++ L
Sbjct 179 LVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKAL------PSLKELGFH 232
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
++ +S + F G L + L N L+ VGN +F L L + ++ F +
Sbjct 233 SNSISVIPDGAFDGNPL--LRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPN 290
Query 317 SLHGLFNVRYLNLKRS--------FTKQSISLASLP----KIDDF-SFQWLKCLEHLNME 363
L G ++ L L + ++ L +L I D SF LE ++++
Sbjct 291 -LTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEISLQ 349
Query 364 DNDIPGIKSNMFTGLINLKYLSLSN 388
N I IK F GLI+L+ L L++
Sbjct 350 RNQIYQIKEGTFQGLISLRILDLAS 374
Score = 90.1 bits (222), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 104/421 (25%), Positives = 180/421 (43%), Gaps = 77/421 (18%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK--- 335
LD+S NN+ + +F P LE L N++ + +L GL ++ L L+ + K
Sbjct 38 LDISMNNITQLPEGAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 97
Query 336 ----------QSISLAS--LPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
QS+ L + + + + SF+ L L HL ++DN + + + + L L+
Sbjct 98 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 157
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L+L+ + ++ + F +L S L +L+L NKI + F L +LE LDL N +
Sbjct 158 LTLA--LNKISSIPDFAFTNL--SSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNL 213
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS----- 498
G+ Q + L ++ E+ N + +F P L+ + L L V +S
Sbjct 214 GE--FPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNL 271
Query 499 ----------PSPFQPLRNLT------ILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
S Q NLT L L+ I++I +++ + + L LDL +NN+
Sbjct 272 SDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNI 331
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLP 602
L P + G L ++L+ N +I F+ L L+I+DL N L ++P
Sbjct 332 RDL--------PSF--NGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLASNQLKSVP 381
Query 603 ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWIN 662
+F+ SL+ + L NP+DC+C I + W+N
Sbjct 382 DGIFDRLTSLQKIWLHT-------------------------NPWDCSCPRIDYLSRWLN 416
Query 663 E 663
+
Sbjct 417 K 417
>3wpg_A A Toll-like receptor 9
Length=803
Score = 96.3 bits (238), Expect = 7e-19, Method: Compositional matrix adjust.
Identities = 186/792 (23%), Positives = 300/792 (38%), Gaps = 152/792 (19%)
Query 34 VADCSHLKLTQVPD----DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
+ DC+ L L VP +NIT L+L N++ L ++F S L L++ +N
Sbjct 21 LVDCNWLFLKSVPRFXXXASCSNITRLSLISNRIHHLHNSDFVHLSNLRQLNLKWNCPPT 80
Query 90 ------------LEPELCQKLPMLKVLNLQHNELSQ--------------------LSDK 117
+EP + L+ LNL +N ++ L
Sbjct 81 GXXXXXXSCHMTIEPRTFLAMRTLEELNLSYNGITTVPRLPSSLVNLSLSHTNILVLDAN 140
Query 118 TFAFCTNLTELHLMSNSIQK------IKNNP--FVKQKNLITLDLSHNGLSSTKLGTQVQ 169
+ A +L L + N K +K P + L L L +N L TK+ Q+
Sbjct 141 SLAGLYSLRVLFMDGNCYYKNPCTGAVKVTPGALLGLSQLTHLSLKYNNL--TKVPRQLP 198
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
+L+ LL+S N I L E+L +SL+ L++ N + C HA
Sbjct 199 -PSLEYLLVSYNLIVKLGPEDLAQL--TSLRVLDVGGNCRR-----CDHAPNPCIECGQK 250
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--N 287
++ L P L + + L L +S L T +++ F GL L++LDLS N L +
Sbjct 251 SLHLHPETFHHL------SHLEGLVLKDSSLHTLNSSWFQGL--VQLSVLDLSENFLYES 302
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH------GLFNVRYLNLK----RSFTKQS 337
+ ++F L +L L +N + LH L +++ LN+ R K +
Sbjct 303 ITHTNAFQNLTRLRKLNLSFNYRKXXXXARLHLASSFKNLVSLQELNMNGIFFRLLNKYT 362
Query 338 IS-LASLPKIDDFSFQW-------------LKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
+ LA LPK+ Q + L +++ DN I G +
Sbjct 363 LRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRISGPSTXXXXXXXXXXX 422
Query 384 LSLSNSFTSLRTLTNETF------VSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
+ + ++L++N + I+ + F L L+ L
Sbjct 423 XXXXXXXXXXXXXXXXXXXXXXXXMDRCKNFKFTMDLSRNNLVTIKPEMFVQLSRLQCLS 482
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML----RRVALK 493
L N I Q + G ++ L N+ + LS+NK SF+ +P LQ L L +
Sbjct 483 LSHNSIAQAVNGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSQXXXXX 542
Query 494 NVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ S L L L L++N+I L + LD N + R+W G
Sbjct 543 GIGHQFSFVTHLSMLQSLSLAHNDIHTRVSSHLNS-NSVRFLDFSGNGMGRMWDEG--GL 599
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKD-------------------------LFEL 588
++F +GLS L L+L N + + + L L
Sbjct 600 YLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLKLLSLRDNYLSFFNWTSLSFLPNL 659
Query 589 KIIDLGLNNL-----NTLP-------------------ASVFNNQVSLKSLNLQKNLITS 624
+++DL N L TLP + F V LK +NL N++ +
Sbjct 660 EVLDLAGNQLKALTQGTLPNGTLLQKLDVSSNSIVSVVPAFFALAVELKEVNLSHNILKT 719
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYH 684
V++ FGP LT LD+R NP C C A FV+ + E T +P L++ C +P
Sbjct 720 VDRSWFGPIVMQLTVLDVRSNPLHCACG--AAFVDLLLEVQTKVPGLANGVKCGSPGQLQ 777
Query 685 GFPVRLFDTSSC 696
G + D C
Sbjct 778 GRSIFAQDLRLC 789
>3wph_A A Toll-like receptor 9
Length=803
Score = 95.5 bits (236), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 186/792 (23%), Positives = 298/792 (38%), Gaps = 152/792 (19%)
Query 34 VADCSHLKLTQVPD----DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
+ DC+ L L VP +NIT L+L N++ L ++F S L L++ +N
Sbjct 21 LVDCNWLFLKSVPRFXXXASCSNITRLSLISNRIHHLHNSDFVHLSNLRQLNLKWNCPPT 80
Query 90 ------------LEPELCQKLPMLKVLNLQHNELSQ--------------------LSDK 117
+EP + L+ LNL +N ++ L
Sbjct 81 GXXXXXXSCHMTIEPRTFLAMRTLEELNLSYNGITTVPRLPSSLVNLSLSHTNILVLDAN 140
Query 118 TFAFCTNLTELHLMSNSIQK------IKNNP--FVKQKNLITLDLSHNGLSSTKLGTQVQ 169
+ A +L L + N K +K P + L L L +N L TK+ Q+
Sbjct 141 SLAGLYSLRVLFMDGNCYYKNPCTGAVKVTPGALLGLSQLTHLSLKYNNL--TKVPRQLP 198
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
+L+ LL+S N I L E+L +SL+ L++ N + C HA
Sbjct 199 -PSLEYLLVSYNLIVKLGPEDLAQL--TSLRVLDVGGNCRR-----CDHAPNPCIECGQK 250
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--N 287
++ L P L + + L L +S L T +++ F GL L++LDLS N L +
Sbjct 251 SLHLHPETFHHL------SHLEGLVLKDSSLHTLNSSWFQGL--VQLSVLDLSENFLYES 302
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH------GLFNVRYLNLK----RSFTKQS 337
+ ++F L +L L +N LH L +++ LN+ R K +
Sbjct 303 ITHTNAFQNLTRLRKLNLSFNYXXXXXXARLHLASSFKNLVSLQELNMNGIFFRLLNKYT 362
Query 338 IS-LASLPKIDDFSFQW-------------LKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
+ LA LPK+ Q + L +++ DN I G +
Sbjct 363 LRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRISGPSTXXXXXXXXXXX 422
Query 384 LSLSNSFTSLRTLTNETF------VSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
+ + ++L++N + I+ + F L L+ L
Sbjct 423 XXXXXXXXXXXXXXXXXXXXXXXXMDRCKNFKFTMDLSRNNLVTIKPEMFVQLSRLQCLS 482
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLR----RVALK 493
L N I Q + G ++ L N+ + LS+NK SF+ +P LQ L L
Sbjct 483 LSHNSIAQAVNGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSXXXXXX 542
Query 494 NVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ S L L L L++N+I L + LD N + R+W G
Sbjct 543 GIGHQFSFVTHLSMLQSLSLAHNDIHTRVSSHLNS-NSVRFLDFSGNGMGRMWDEG--GL 599
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKD-------------------------LFEL 588
++F +GLS L L+L N + + + L L
Sbjct 600 YLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLKLLSLRDNYLSFFNWTSLSFLPNL 659
Query 589 KIIDLGLNNL-----NTLP-------------------ASVFNNQVSLKSLNLQKNLITS 624
+++DL N L TLP + F V LK +NL N++ +
Sbjct 660 EVLDLAGNQLKALTQGTLPNGTLLQKLDVSSNSIVSVVPAFFALAVELKEVNLSHNILKT 719
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYH 684
V++ FGP LT LD+R NP C C A FV+ + E T +P L++ C +P
Sbjct 720 VDRSWFGPIVMQLTVLDVRSNPLHCACG--AAFVDLLLEVQTKVPGLANGVKCGSPGQLQ 777
Query 685 GFPVRLFDTSSC 696
G + D C
Sbjct 778 GRSIFAQDLRLC 789
>3wpd_A A Toll-like receptor 9
Length=802
Score = 92.4 bits (228), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 168/671 (25%), Positives = 247/671 (37%), Gaps = 88/671 (13%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPML 101
LT VP LP ++ L L++N + L + + L LDVG N C++
Sbjct 190 LTTVPRSLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGN---------CRRCDHA 240
Query 102 K--VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
+ + H + QL TF+ + L L L +S+ ++ F NL LDLS N L
Sbjct 241 RNPCVECPH-KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFL 299
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
T+ Q L + L++L LS N K+ S
Sbjct 300 YDCITKTKA--------------FQGL----------AQLRRLNLSFNYHKKVS------ 329
Query 220 IGRLFGLFLNNVQLGPSLTEKLCL-ELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
++ L PS L L EL I SLS L + + L
Sbjct 330 --------FAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLA-------RLPMLQR 374
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L N +N F P L Y L N I
Sbjct 375 LYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXXXXXXXXXX 434
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+DF L++ N++ ++ MF L L+ L LS++ S + +
Sbjct 435 XXXXXXXXEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNSIS-QAVNG 493
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
FV L + L +L+L+ NK+ +F+ L LE LDL N + G G
Sbjct 494 SQFVPL--TSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGV---GHNLS 548
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP-----------FQPLRN 507
F L +YL L N S Q AL +S S FQ LR+
Sbjct 549 FVAQLPTLRYLSLAHNGIHSRVSQQLCSTSLWALDFSGNSLSQMWAEGDLYLRFFQGLRS 608
Query 508 LTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLH 565
L LDLS N + + L L K L++L L++N LA W L L +L
Sbjct 609 LIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSS---------LTLLPNLE 659
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L N + +L+ +D+ N++ + F L+ LNL N + +V
Sbjct 660 TLDLAGNQLKALSNGSLPSGTQLQRLDVSRNSIIFVVPGFFALATRLRELNLSANALRTV 719
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
E FG +L LD+ NP C C A FV+++ + +P L S C +P G
Sbjct 720 EPSWFGFLAGSLEVLDVSANPLHCACG--AAFVDFLLQVQAAVPGLPSRVKCGSPGQLQG 777
Query 686 FPVRLFDTSSC 696
+ D C
Sbjct 778 RSIFAQDLRLC 788
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 139/540 (26%), Positives = 209/540 (39%), Gaps = 113/540 (21%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE-------- 171
N+T L L+SN I + ++ F + NL L+L N GLS + +E
Sbjct 43 NVTSLSLLSNRIHHLHDSDFAQLSNLQKLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVP 102
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L+EL LS N I + + SSL L LS I + P + L L+++
Sbjct 103 TLEELNLSYNGITTVPALP------SSLVSLILSRTNILQLDPTSLTGLHALRFLYMD-- 154
Query 232 QLGPSLTEKLC---LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
G + C LE+A ++ LGL NLT L L YNNL
Sbjct 155 --GNCYYKNPCGRALEVAPGAL------------------LGLG--NLTHLSLKYNNLTT 192
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL----NLKRSFTKQSISLA--- 341
V + P LEY L YN+I L L L +R L N +R ++ +
Sbjct 193 VPR---SLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCVECPH 249
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
P++ +F L LE L ++D+ + + F GL NL L LS +F + F
Sbjct 250 KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFLYDCITKTKAF 309
Query 402 VSLAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLG---LNEIGQELTGQEW 452
LA L LNL+ N K+ + +F L L+ LD+ + Q+ T Q
Sbjct 310 QGLAQ--LRRLNLSFNYHKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQK-TLQPL 366
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV----------------- 495
L + +YL N Q F P L+ + L +
Sbjct 367 ARLPMLQRLYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXX 426
Query 496 -----------------DSSPSPFQPLRNLTI-LDLSNNNIANINDDMLEGLEKLEILDL 537
D PS +NL+ LDLS NN+ + +M L +L+ L L
Sbjct 427 XXXXXXXXXXXXXXXXEDFMPS----CKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRL 482
Query 538 QHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNN 597
HN++++ + L+ L +L+L N D F +L L+ +DL N+
Sbjct 483 SHNSISQAVNGSQ-------FVPLTSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNS 535
>3wpb_A A Toll-like receptor 9
Length=802
Score = 92.4 bits (228), Expect = 9e-18, Method: Compositional matrix adjust.
Identities = 168/671 (25%), Positives = 247/671 (37%), Gaps = 88/671 (13%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPML 101
LT VP LP ++ L L++N + L + + L LDVG N C++
Sbjct 190 LTTVPRSLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGN---------CRRCDHA 240
Query 102 K--VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
+ + H + QL TF+ + L L L +S+ ++ F NL LDLS N L
Sbjct 241 RNPCVECPH-KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFL 299
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
T+ Q L + L++L LS N K+ S
Sbjct 300 YDCITKTKA--------------FQGL----------AQLRRLNLSFNYHKKVS------ 329
Query 220 IGRLFGLFLNNVQLGPSLTEKLCL-ELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
++ L PS L L EL I SLS L + + L
Sbjct 330 --------FAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLA-------RLPMLQR 374
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L N +N F P L Y L N I
Sbjct 375 LYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXXXXXXXXXX 434
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+DF L++ N++ ++ MF L L+ L LS++ S + +
Sbjct 435 XXXXXXXXEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNSIS-QAVNG 493
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
FV L + L +L+L+ NK+ +F+ L LE LDL N + G G
Sbjct 494 SQFVPL--TSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGV---GHNLS 548
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP-----------FQPLRN 507
F L +YL L N S Q AL +S S FQ LR+
Sbjct 549 FVAQLPTLRYLSLAHNGIHSRVSQQLCSTSLWALDFSGNSLSQMWAEGDLYLRFFQGLRS 608
Query 508 LTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLH 565
L LDLS N + + L L K L++L L++N LA W L L +L
Sbjct 609 LIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSS---------LTLLPNLE 659
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L N + +L+ +D+ N++ + F L+ LNL N + +V
Sbjct 660 TLDLAGNQLKALSNGSLPSGTQLQRLDVSRNSIIFVVPGFFALATRLRELNLSANALRTV 719
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
E FG +L LD+ NP C C A FV+++ + +P L S C +P G
Sbjct 720 EPSWFGFLAGSLEVLDVSANPLHCACG--AAFVDFLLQVQAAVPGLPSRVKCGSPGQLQG 777
Query 686 FPVRLFDTSSC 696
+ D C
Sbjct 778 RSIFAQDLRLC 788
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 139/540 (26%), Positives = 209/540 (39%), Gaps = 113/540 (21%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE-------- 171
N+T L L+SN I + ++ F + NL L+L N GLS + +E
Sbjct 43 NVTSLSLLSNRIHHLHDSDFAQLSNLQKLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVP 102
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L+EL LS N I + + SSL L LS I + P + L L+++
Sbjct 103 TLEELNLSYNGITTVPALP------SSLVSLILSRTNILQLDPTSLTGLHALRFLYMD-- 154
Query 232 QLGPSLTEKLC---LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
G + C LE+A ++ LGL NLT L L YNNL
Sbjct 155 --GNCYYKNPCGRALEVAPGAL------------------LGLG--NLTHLSLKYNNLTT 192
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL----NLKRSFTKQSISLA--- 341
V + P LEY L YN+I L L L +R L N +R ++ +
Sbjct 193 VPR---SLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCVECPH 249
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
P++ +F L LE L ++D+ + + F GL NL L LS +F + F
Sbjct 250 KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFLYDCITKTKAF 309
Query 402 VSLAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLG---LNEIGQELTGQEW 452
LA L LNL+ N K+ + +F L L+ LD+ + Q+ T Q
Sbjct 310 QGLAQ--LRRLNLSFNYHKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQK-TLQPL 366
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV----------------- 495
L + +YL N Q F P L+ + L +
Sbjct 367 ARLPMLQRLYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXX 426
Query 496 -----------------DSSPSPFQPLRNLTI-LDLSNNNIANINDDMLEGLEKLEILDL 537
D PS +NL+ LDLS NN+ + +M L +L+ L L
Sbjct 427 XXXXXXXXXXXXXXXXEDFMPS----CKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRL 482
Query 538 QHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNN 597
HN++++ + L+ L +L+L N D F +L L+ +DL N+
Sbjct 483 SHNSISQAVNGSQ-------FVPLTSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNS 535
>3wpc_B B Toll-like receptor 9
Length=802
Score = 92.0 bits (227), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 166/660 (25%), Positives = 244/660 (37%), Gaps = 88/660 (13%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPML 101
LT VP LP ++ L L++N + L + + L LDVG N C++
Sbjct 190 LTTVPRSLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGN---------CRRCDHA 240
Query 102 K--VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
+ + H + QL TF+ + L L L +S+ ++ F NL LDLS N L
Sbjct 241 RNPCVECPH-KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFL 299
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
T+ Q L + L++L LS N K+ S
Sbjct 300 YDCITKTKA--------------FQGL----------AQLRRLNLSFNYHKKVS------ 329
Query 220 IGRLFGLFLNNVQLGPSLTEKLCL-ELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
++ L PS L L EL I SLS L + + L
Sbjct 330 --------FAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLA-------RLPMLQR 374
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L N +N F P L Y L N I
Sbjct 375 LYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXXXXXXXXXX 434
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+DF L++ N++ ++ MF L L+ L LS++ S + +
Sbjct 435 XXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNSIS-QAVNG 493
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
FV L + L +L+L+ NK+ +F+ L LE LDL N + G G
Sbjct 494 SQFVPL--TSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGV---GHNLS 548
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP-----------FQPLRN 507
F L +YL L N S Q AL +S S FQ LR+
Sbjct 549 FVAQLPTLRYLSLAHNGIHSRVSQQLCSTSLWALDFSGNSLSQMWAEGDLYLRFFQGLRS 608
Query 508 LTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLH 565
L LDLS N + + L L K L++L L++N LA W L L +L
Sbjct 609 LIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSS---------LTLLPNLE 659
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L N + +L+ +D+ N++ + F L+ LNL N + +V
Sbjct 660 TLDLAGNQLKALSNGSLPSGTQLQRLDVSRNSIIFVVPGFFALATRLRELNLSANALRTV 719
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
E FG +L LD+ NP C C A FV+++ + +P L S C +P G
Sbjct 720 EPSWFGFLAGSLEVLDVSANPLHCACG--AAFVDFLLQVQAAVPGLPSRVKCGSPGQLQG 777
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 138/536 (26%), Positives = 208/536 (39%), Gaps = 105/536 (20%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE-------- 171
N+T L L+SN I + ++ F + NL L+L N GLS + +E
Sbjct 43 NVTSLSLLSNRIHHLHDSDFAQLSNLQKLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVP 102
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L+EL LS N I + + SSL L LS I + P + L L+++
Sbjct 103 TLEELNLSYNGITTVPALP------SSLVSLILSRTNILQLDPTSLTGLHALRFLYMD-- 154
Query 232 QLGPSLTEKLC---LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
G + C LE+A ++ LGL NLT L L YNNL
Sbjct 155 --GNCYYKNPCGRALEVAPGAL------------------LGLG--NLTHLSLKYNNLTT 192
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL----NLKRSFTKQSISLA--- 341
V + P LEY L YN+I L L L +R L N +R ++ +
Sbjct 193 VPR---SLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCVECPH 249
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
P++ +F L LE L ++D+ + + F GL NL L LS +F + F
Sbjct 250 KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFLYDCITKTKAF 309
Query 402 VSLAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLG---LNEIGQELTGQEW 452
LA L LNL+ N K+ + +F L L+ LD+ + Q+ T Q
Sbjct 310 QGLAQ--LRRLNLSFNYHKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQK-TLQPL 366
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV----------------- 495
L + +YL N Q F P L+ + L +
Sbjct 367 ARLPMLQRLYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXX 426
Query 496 ------------DSSPSPFQP-LRNLTI-LDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
F P +NL+ LDLS NN+ + +M L +L+ L L HN+
Sbjct 427 XXXXXXXXXXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNS 486
Query 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNN 597
+++ + L+ L +L+L N D F +L L+ +DL N+
Sbjct 487 ISQAVNGSQ-------FVPLTSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNS 535
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 96/383 (25%), Positives = 152/383 (40%), Gaps = 70/383 (18%)
Query 255 LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN---VVGNDSFAWLPQLEYFFLEYNNIQ 311
L +S + SN L LKW N LS + + ++F +P LE L YN I
Sbjct 57 LHDSDFAQLSNLQKLNLKW-NCPPAGLSPMHFPCHMTIEPNTFLAVPTLEELNLSYNGIT 115
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN------ 365
+ + L S +S ++ ++D S L L L M+ N
Sbjct 116 TVPA-------------LPSSLVSLILSRTNILQLDPTSLTGLHALRFLYMDGNCYYKNP 162
Query 366 --DIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
+ GL NL +LSL + +L T+ SL + L L+ N I +
Sbjct 163 CGRALEVAPGALLGLGNLTHLSLK--YNNLTTVPRSLPPSLEY-----LLLSYNHIVTLA 215
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
+ + L L VLD+G G R +K+ QL ++F+ + L+
Sbjct 216 PEDLANLTALRVLDVG---------GNCRRCDHARNPCVECPHKFPQLHSDTFSHLSRLE 266
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI--NDDMLEGLEKLEILDLQHN- 540
L+L+ +L ++ P F+ L NLT+LDLS N + + +GL +L L+L N
Sbjct 267 GLVLKDSSLYQLN--PRWFRGLGNLTVLDLSENFLYDCITKTKAFQGLAQLRRLNLSFNY 324
Query 541 ----NLARLWKHANPGG----------PIYF----------LKGLSHLHILNLESNGFDE 576
+ A L + G I+F L L L L L+ N ++
Sbjct 325 HKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLARLPMLQRLYLQMNFINQ 384
Query 577 IPVEVFKDLFELKIIDLGLNNLN 599
+ +FKD L+ IDL N ++
Sbjct 385 AQLGIFKDFPGLRYIDLSDNRIS 407
>5y3l_A A Toll-like receptor 9
Length=802
Score = 91.7 bits (226), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 166/660 (25%), Positives = 244/660 (37%), Gaps = 88/660 (13%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPML 101
LT VP LP ++ L L++N + L + + L LDVG N C++
Sbjct 190 LTTVPRSLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGN---------CRRCDHA 240
Query 102 K--VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
+ + H + QL TF+ + L L L +S+ ++ F NL LDLS N L
Sbjct 241 RNPCVECPH-KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFL 299
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
T+ Q L + L++L LS N K+ S
Sbjct 300 YDCITKTKA--------------FQGL----------AQLRRLNLSFNYHKKVS------ 329
Query 220 IGRLFGLFLNNVQLGPSLTEKLCL-ELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
++ L PS L L EL I SLS L + + L
Sbjct 330 --------FAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLA-------RLPMLQR 374
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L N +N F P L Y L N I
Sbjct 375 LYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXXXXXXXXXX 434
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+DF L++ N++ ++ MF L L+ L LS++ S + +
Sbjct 435 XXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNSIS-QAVNG 493
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
FV L + L +L+L+ NK+ +F+ L LE LDL N + G G
Sbjct 494 SQFVPL--TSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGV---GHNLS 548
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP-----------FQPLRN 507
F L +YL L N S Q AL +S S FQ LR+
Sbjct 549 FVAQLPTLRYLSLAHNGIHSRVSQQLCSTSLWALDFSGNSLSQMWAEGDLYLRFFQGLRS 608
Query 508 LTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLH 565
L LDLS N + + L L K L++L L++N LA W L L +L
Sbjct 609 LIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSS---------LTLLPNLE 659
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L N + +L+ +D+ N++ + F L+ LNL N + +V
Sbjct 660 TLDLAGNQLKALSNGSLPSGTQLQRLDVSRNSIIFVVPGFFALATRLRELNLSANALRTV 719
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
E FG +L LD+ NP C C A FV+++ + +P L S C +P G
Sbjct 720 EPSWFGFLAGSLEVLDVSANPLHCACG--AAFVDFLLQVQAAVPGLPSRVKCGSPGQLQG 777
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 138/536 (26%), Positives = 208/536 (39%), Gaps = 105/536 (20%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE-------- 171
N+T L L+SN I + ++ F + NL L+L N GLS + +E
Sbjct 43 NVTSLSLLSNRIHHLHDSDFAQLSNLQKLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVP 102
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L+EL LS N I + + SSL L LS I + P + L L+++
Sbjct 103 TLEELNLSYNGITTVPALP------SSLVSLILSRTNILQLDPTSLTGLHALRFLYMD-- 154
Query 232 QLGPSLTEKLC---LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
G + C LE+A ++ LGL NLT L L YNNL
Sbjct 155 --GNCYYKNPCGRALEVAPGAL------------------LGLG--NLTHLSLKYNNLTT 192
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL----NLKRSFTKQSISLA--- 341
V + P LEY L YN+I L L L +R L N +R ++ +
Sbjct 193 VPR---SLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCVECPH 249
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
P++ +F L LE L ++D+ + + F GL NL L LS +F + F
Sbjct 250 KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFLYDCITKTKAF 309
Query 402 VSLAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLG---LNEIGQELTGQEW 452
LA L LNL+ N K+ + +F L L+ LD+ + Q+ T Q
Sbjct 310 QGLAQ--LRRLNLSFNYHKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQK-TLQPL 366
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV----------------- 495
L + +YL N Q F P L+ + L +
Sbjct 367 ARLPMLQRLYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXX 426
Query 496 ------------DSSPSPFQP-LRNLTI-LDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
F P +NL+ LDLS NN+ + +M L +L+ L L HN+
Sbjct 427 XXXXXXXXXXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNS 486
Query 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNN 597
+++ + L+ L +L+L N D F +L L+ +DL N+
Sbjct 487 ISQAVNGSQ-------FVPLTSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNS 535
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 96/383 (25%), Positives = 152/383 (40%), Gaps = 70/383 (18%)
Query 255 LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN---VVGNDSFAWLPQLEYFFLEYNNIQ 311
L +S + SN L LKW N LS + + ++F +P LE L YN I
Sbjct 57 LHDSDFAQLSNLQKLNLKW-NCPPAGLSPMHFPCHMTIEPNTFLAVPTLEELNLSYNGIT 115
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN------ 365
+ + L S +S ++ ++D S L L L M+ N
Sbjct 116 TVPA-------------LPSSLVSLILSRTNILQLDPTSLTGLHALRFLYMDGNCYYKNP 162
Query 366 --DIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
+ GL NL +LSL + +L T+ SL + L L+ N I +
Sbjct 163 CGRALEVAPGALLGLGNLTHLSLK--YNNLTTVPRSLPPSLEY-----LLLSYNHIVTLA 215
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
+ + L L VLD+G G R +K+ QL ++F+ + L+
Sbjct 216 PEDLANLTALRVLDVG---------GNCRRCDHARNPCVECPHKFPQLHSDTFSHLSRLE 266
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI--NDDMLEGLEKLEILDLQHN- 540
L+L+ +L ++ P F+ L NLT+LDLS N + + +GL +L L+L N
Sbjct 267 GLVLKDSSLYQLN--PRWFRGLGNLTVLDLSENFLYDCITKTKAFQGLAQLRRLNLSFNY 324
Query 541 ----NLARLWKHANPGG----------PIYF----------LKGLSHLHILNLESNGFDE 576
+ A L + G I+F L L L L L+ N ++
Sbjct 325 HKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLARLPMLQRLYLQMNFINQ 384
Query 577 IPVEVFKDLFELKIIDLGLNNLN 599
+ +FKD L+ IDL N ++
Sbjct 385 AQLGIFKDFPGLRYIDLSDNRIS 407
>5y3j_B B Toll-like receptor 9
Length=802
Score = 91.7 bits (226), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 166/660 (25%), Positives = 244/660 (37%), Gaps = 88/660 (13%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPML 101
LT VP LP ++ L L++N + L + + L LDVG N C++
Sbjct 190 LTTVPRSLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGN---------CRRCDHA 240
Query 102 K--VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
+ + H + QL TF+ + L L L +S+ ++ F NL LDLS N L
Sbjct 241 RNPCVECPH-KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFL 299
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
T+ Q L + L++L LS N K+ S
Sbjct 300 YDCITKTKA--------------FQGL----------AQLRRLNLSFNYHKKVS------ 329
Query 220 IGRLFGLFLNNVQLGPSLTEKLCL-ELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
++ L PS L L EL I SLS L + + L
Sbjct 330 --------FAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLA-------RLPMLQR 374
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L N +N F P L Y L N I
Sbjct 375 LYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXXXXXXXXXX 434
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+DF L++ N++ ++ MF L L+ L LS++ S + +
Sbjct 435 XXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNSIS-QAVNG 493
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
FV L + L +L+L+ NK+ +F+ L LE LDL N + G G
Sbjct 494 SQFVPL--TSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGV---GHNLS 548
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP-----------FQPLRN 507
F L +YL L N S Q AL +S S FQ LR+
Sbjct 549 FVAQLPTLRYLSLAHNGIHSRVSQQLCSTSLWALDFSGNSLSQMWAEGDLYLRFFQGLRS 608
Query 508 LTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLH 565
L LDLS N + + L L K L++L L++N LA W L L +L
Sbjct 609 LIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSS---------LTLLPNLE 659
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L N + +L+ +D+ N++ + F L+ LNL N + +V
Sbjct 660 TLDLAGNQLKALSNGSLPSGTQLQRLDVSRNSIIFVVPGFFALATRLRELNLSANALRTV 719
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
E FG +L LD+ NP C C A FV+++ + +P L S C +P G
Sbjct 720 EPSWFGFLAGSLEVLDVSANPLHCACG--AAFVDFLLQVQAAVPGLPSRVKCGSPGQLQG 777
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 138/536 (26%), Positives = 208/536 (39%), Gaps = 105/536 (20%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE-------- 171
N+T L L+SN I + ++ F + NL L+L N GLS + +E
Sbjct 43 NVTSLSLLSNRIHHLHDSDFAQLSNLQKLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVP 102
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L+EL LS N I + + SSL L LS I + P + L L+++
Sbjct 103 TLEELNLSYNGITTVPALP------SSLVSLILSRTNILQLDPTSLTGLHALRFLYMD-- 154
Query 232 QLGPSLTEKLC---LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
G + C LE+A ++ LGL NLT L L YNNL
Sbjct 155 --GNCYYKNPCGRALEVAPGAL------------------LGLG--NLTHLSLKYNNLTT 192
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL----NLKRSFTKQSISLA--- 341
V + P LEY L YN+I L L L +R L N +R ++ +
Sbjct 193 VPR---SLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCVECPH 249
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
P++ +F L LE L ++D+ + + F GL NL L LS +F + F
Sbjct 250 KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFLYDCITKTKAF 309
Query 402 VSLAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLG---LNEIGQELTGQEW 452
LA L LNL+ N K+ + +F L L+ LD+ + Q+ T Q
Sbjct 310 QGLAQ--LRRLNLSFNYHKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQK-TLQPL 366
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV----------------- 495
L + +YL N Q F P L+ + L +
Sbjct 367 ARLPMLQRLYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXX 426
Query 496 ------------DSSPSPFQP-LRNLTI-LDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
F P +NL+ LDLS NN+ + +M L +L+ L L HN+
Sbjct 427 XXXXXXXXXXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNS 486
Query 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNN 597
+++ + L+ L +L+L N D F +L L+ +DL N+
Sbjct 487 ISQAVNGSQ-------FVPLTSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNS 535
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 96/383 (25%), Positives = 152/383 (40%), Gaps = 70/383 (18%)
Query 255 LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN---VVGNDSFAWLPQLEYFFLEYNNIQ 311
L +S + SN L LKW N LS + + ++F +P LE L YN I
Sbjct 57 LHDSDFAQLSNLQKLNLKW-NCPPAGLSPMHFPCHMTIEPNTFLAVPTLEELNLSYNGIT 115
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN------ 365
+ + L S +S ++ ++D S L L L M+ N
Sbjct 116 TVPA-------------LPSSLVSLILSRTNILQLDPTSLTGLHALRFLYMDGNCYYKNP 162
Query 366 --DIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
+ GL NL +LSL + +L T+ SL + L L+ N I +
Sbjct 163 CGRALEVAPGALLGLGNLTHLSLK--YNNLTTVPRSLPPSLEY-----LLLSYNHIVTLA 215
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
+ + L L VLD+G G R +K+ QL ++F+ + L+
Sbjct 216 PEDLANLTALRVLDVG---------GNCRRCDHARNPCVECPHKFPQLHSDTFSHLSRLE 266
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI--NDDMLEGLEKLEILDLQHN- 540
L+L+ +L ++ P F+ L NLT+LDLS N + + +GL +L L+L N
Sbjct 267 GLVLKDSSLYQLN--PRWFRGLGNLTVLDLSENFLYDCITKTKAFQGLAQLRRLNLSFNY 324
Query 541 ----NLARLWKHANPGG----------PIYF----------LKGLSHLHILNLESNGFDE 576
+ A L + G I+F L L L L L+ N ++
Sbjct 325 HKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLARLPMLQRLYLQMNFINQ 384
Query 577 IPVEVFKDLFELKIIDLGLNNLN 599
+ +FKD L+ IDL N ++
Sbjct 385 AQLGIFKDFPGLRYIDLSDNRIS 407
>5y3l_D B Toll-like receptor 9
Length=802
Score = 91.7 bits (226), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 166/660 (25%), Positives = 244/660 (37%), Gaps = 88/660 (13%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPML 101
LT VP LP ++ L L++N + L + + L LDVG N C++
Sbjct 190 LTTVPRSLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGN---------CRRCDHA 240
Query 102 K--VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
+ + H + QL TF+ + L L L +S+ ++ F NL LDLS N L
Sbjct 241 RNPCVECPH-KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFL 299
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
T+ Q L + L++L LS N K+ S
Sbjct 300 YDCITKTKA--------------FQGL----------AQLRRLNLSFNYHKKVS------ 329
Query 220 IGRLFGLFLNNVQLGPSLTEKLCL-ELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
++ L PS L L EL I SLS L + + L
Sbjct 330 --------FAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLA-------RLPMLQR 374
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L N +N F P L Y L N I
Sbjct 375 LYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXXXXXXXXXX 434
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+DF L++ N++ ++ MF L L+ L LS++ S + +
Sbjct 435 XXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNSIS-QAVNG 493
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
FV L + L +L+L+ NK+ +F+ L LE LDL N + G G
Sbjct 494 SQFVPL--TSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGV---GHNLS 548
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP-----------FQPLRN 507
F L +YL L N S Q AL +S S FQ LR+
Sbjct 549 FVAQLPTLRYLSLAHNGIHSRVSQQLCSTSLWALDFSGNSLSQMWAEGDLYLRFFQGLRS 608
Query 508 LTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLH 565
L LDLS N + + L L K L++L L++N LA W L L +L
Sbjct 609 LIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSS---------LTLLPNLE 659
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L N + +L+ +D+ N++ + F L+ LNL N + +V
Sbjct 660 TLDLAGNQLKALSNGSLPSGTQLQRLDVSRNSIIFVVPGFFALATRLRELNLSANALRTV 719
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
E FG +L LD+ NP C C A FV+++ + +P L S C +P G
Sbjct 720 EPSWFGFLAGSLEVLDVSANPLHCACG--AAFVDFLLQVQAAVPGLPSRVKCGSPGQLQG 777
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 138/536 (26%), Positives = 208/536 (39%), Gaps = 105/536 (20%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE-------- 171
N+T L L+SN I + ++ F + NL L+L N GLS + +E
Sbjct 43 NVTSLSLLSNRIHHLHDSDFAQLSNLQKLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVP 102
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L+EL LS N I + + SSL L LS I + P + L L+++
Sbjct 103 TLEELNLSYNGITTVPALP------SSLVSLILSRTNILQLDPTSLTGLHALRFLYMD-- 154
Query 232 QLGPSLTEKLC---LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
G + C LE+A ++ LGL NLT L L YNNL
Sbjct 155 --GNCYYKNPCGRALEVAPGAL------------------LGLG--NLTHLSLKYNNLTT 192
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL----NLKRSFTKQSISLA--- 341
V + P LEY L YN+I L L L +R L N +R ++ +
Sbjct 193 VPR---SLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCVECPH 249
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
P++ +F L LE L ++D+ + + F GL NL L LS +F + F
Sbjct 250 KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFLYDCITKTKAF 309
Query 402 VSLAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLG---LNEIGQELTGQEW 452
LA L LNL+ N K+ + +F L L+ LD+ + Q+ T Q
Sbjct 310 QGLAQ--LRRLNLSFNYHKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQK-TLQPL 366
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV----------------- 495
L + +YL N Q F P L+ + L +
Sbjct 367 ARLPMLQRLYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXX 426
Query 496 ------------DSSPSPFQP-LRNLTI-LDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
F P +NL+ LDLS NN+ + +M L +L+ L L HN+
Sbjct 427 XXXXXXXXXXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNS 486
Query 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNN 597
+++ + L+ L +L+L N D F +L L+ +DL N+
Sbjct 487 ISQAVNGSQ-------FVPLTSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNS 535
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 96/383 (25%), Positives = 152/383 (40%), Gaps = 70/383 (18%)
Query 255 LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN---VVGNDSFAWLPQLEYFFLEYNNIQ 311
L +S + SN L LKW N LS + + ++F +P LE L YN I
Sbjct 57 LHDSDFAQLSNLQKLNLKW-NCPPAGLSPMHFPCHMTIEPNTFLAVPTLEELNLSYNGIT 115
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN------ 365
+ + L S +S ++ ++D S L L L M+ N
Sbjct 116 TVPA-------------LPSSLVSLILSRTNILQLDPTSLTGLHALRFLYMDGNCYYKNP 162
Query 366 --DIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
+ GL NL +LSL + +L T+ SL + L L+ N I +
Sbjct 163 CGRALEVAPGALLGLGNLTHLSLK--YNNLTTVPRSLPPSLEY-----LLLSYNHIVTLA 215
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
+ + L L VLD+G G R +K+ QL ++F+ + L+
Sbjct 216 PEDLANLTALRVLDVG---------GNCRRCDHARNPCVECPHKFPQLHSDTFSHLSRLE 266
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI--NDDMLEGLEKLEILDLQHN- 540
L+L+ +L ++ P F+ L NLT+LDLS N + + +GL +L L+L N
Sbjct 267 GLVLKDSSLYQLN--PRWFRGLGNLTVLDLSENFLYDCITKTKAFQGLAQLRRLNLSFNY 324
Query 541 ----NLARLWKHANPGG----------PIYF----------LKGLSHLHILNLESNGFDE 576
+ A L + G I+F L L L L L+ N ++
Sbjct 325 HKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLARLPMLQRLYLQMNFINQ 384
Query 577 IPVEVFKDLFELKIIDLGLNNLN 599
+ +FKD L+ IDL N ++
Sbjct 385 AQLGIFKDFPGLRYIDLSDNRIS 407
>5y3k_A A Toll-like receptor 9
Length=802
Score = 91.7 bits (226), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 166/660 (25%), Positives = 244/660 (37%), Gaps = 88/660 (13%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPML 101
LT VP LP ++ L L++N + L + + L LDVG N C++
Sbjct 190 LTTVPRSLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGN---------CRRCDHA 240
Query 102 K--VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
+ + H + QL TF+ + L L L +S+ ++ F NL LDLS N L
Sbjct 241 RNPCVECPH-KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFL 299
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
T+ Q L + L++L LS N K+ S
Sbjct 300 YDCITKTKA--------------FQGL----------AQLRRLNLSFNYHKKVS------ 329
Query 220 IGRLFGLFLNNVQLGPSLTEKLCL-ELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
++ L PS L L EL I SLS L + + L
Sbjct 330 --------FAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLA-------RLPMLQR 374
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L N +N F P L Y L N I
Sbjct 375 LYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXXXXXXXXXX 434
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+DF L++ N++ ++ MF L L+ L LS++ S + +
Sbjct 435 XXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNSIS-QAVNG 493
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
FV L + L +L+L+ NK+ +F+ L LE LDL N + G G
Sbjct 494 SQFVPL--TSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGV---GHNLS 548
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP-----------FQPLRN 507
F L +YL L N S Q AL +S S FQ LR+
Sbjct 549 FVAQLPTLRYLSLAHNGIHSRVSQQLCSTSLWALDFSGNSLSQMWAEGDLYLRFFQGLRS 608
Query 508 LTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLH 565
L LDLS N + + L L K L++L L++N LA W L L +L
Sbjct 609 LIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSS---------LTLLPNLE 659
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L N + +L+ +D+ N++ + F L+ LNL N + +V
Sbjct 660 TLDLAGNQLKALSNGSLPSGTQLQRLDVSRNSIIFVVPGFFALATRLRELNLSANALRTV 719
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
E FG +L LD+ NP C C A FV+++ + +P L S C +P G
Sbjct 720 EPSWFGFLAGSLEVLDVSANPLHCACG--AAFVDFLLQVQAAVPGLPSRVKCGSPGQLQG 777
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 138/536 (26%), Positives = 208/536 (39%), Gaps = 105/536 (20%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE-------- 171
N+T L L+SN I + ++ F + NL L+L N GLS + +E
Sbjct 43 NVTSLSLLSNRIHHLHDSDFAQLSNLQKLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVP 102
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L+EL LS N I + + SSL L LS I + P + L L+++
Sbjct 103 TLEELNLSYNGITTVPALP------SSLVSLILSRTNILQLDPTSLTGLHALRFLYMD-- 154
Query 232 QLGPSLTEKLC---LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
G + C LE+A ++ LGL NLT L L YNNL
Sbjct 155 --GNCYYKNPCGRALEVAPGAL------------------LGLG--NLTHLSLKYNNLTT 192
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL----NLKRSFTKQSISLA--- 341
V + P LEY L YN+I L L L +R L N +R ++ +
Sbjct 193 VPR---SLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCVECPH 249
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
P++ +F L LE L ++D+ + + F GL NL L LS +F + F
Sbjct 250 KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFLYDCITKTKAF 309
Query 402 VSLAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLG---LNEIGQELTGQEW 452
LA L LNL+ N K+ + +F L L+ LD+ + Q+ T Q
Sbjct 310 QGLAQ--LRRLNLSFNYHKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQK-TLQPL 366
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV----------------- 495
L + +YL N Q F P L+ + L +
Sbjct 367 ARLPMLQRLYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXX 426
Query 496 ------------DSSPSPFQP-LRNLTI-LDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
F P +NL+ LDLS NN+ + +M L +L+ L L HN+
Sbjct 427 XXXXXXXXXXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNS 486
Query 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNN 597
+++ + L+ L +L+L N D F +L L+ +DL N+
Sbjct 487 ISQAVNGSQ-------FVPLTSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNS 535
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 96/383 (25%), Positives = 152/383 (40%), Gaps = 70/383 (18%)
Query 255 LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN---VVGNDSFAWLPQLEYFFLEYNNIQ 311
L +S + SN L LKW N LS + + ++F +P LE L YN I
Sbjct 57 LHDSDFAQLSNLQKLNLKW-NCPPAGLSPMHFPCHMTIEPNTFLAVPTLEELNLSYNGIT 115
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN------ 365
+ + L S +S ++ ++D S L L L M+ N
Sbjct 116 TVPA-------------LPSSLVSLILSRTNILQLDPTSLTGLHALRFLYMDGNCYYKNP 162
Query 366 --DIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
+ GL NL +LSL + +L T+ SL + L L+ N I +
Sbjct 163 CGRALEVAPGALLGLGNLTHLSLK--YNNLTTVPRSLPPSLEY-----LLLSYNHIVTLA 215
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
+ + L L VLD+G G R +K+ QL ++F+ + L+
Sbjct 216 PEDLANLTALRVLDVG---------GNCRRCDHARNPCVECPHKFPQLHSDTFSHLSRLE 266
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI--NDDMLEGLEKLEILDLQHN- 540
L+L+ +L ++ P F+ L NLT+LDLS N + + +GL +L L+L N
Sbjct 267 GLVLKDSSLYQLN--PRWFRGLGNLTVLDLSENFLYDCITKTKAFQGLAQLRRLNLSFNY 324
Query 541 ----NLARLWKHANPGG----------PIYF----------LKGLSHLHILNLESNGFDE 576
+ A L + G I+F L L L L L+ N ++
Sbjct 325 HKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLARLPMLQRLYLQMNFINQ 384
Query 577 IPVEVFKDLFELKIIDLGLNNLN 599
+ +FKD L+ IDL N ++
Sbjct 385 AQLGIFKDFPGLRYIDLSDNRIS 407
>5y3j_A A Toll-like receptor 9
Length=802
Score = 91.7 bits (226), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 166/660 (25%), Positives = 244/660 (37%), Gaps = 88/660 (13%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPML 101
LT VP LP ++ L L++N + L + + L LDVG N C++
Sbjct 190 LTTVPRSLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGN---------CRRCDHA 240
Query 102 K--VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
+ + H + QL TF+ + L L L +S+ ++ F NL LDLS N L
Sbjct 241 RNPCVECPH-KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFL 299
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
T+ Q L + L++L LS N K+ S
Sbjct 300 YDCITKTKA--------------FQGL----------AQLRRLNLSFNYHKKVS------ 329
Query 220 IGRLFGLFLNNVQLGPSLTEKLCL-ELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
++ L PS L L EL I SLS L + + L
Sbjct 330 --------FAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLA-------RLPMLQR 374
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L N +N F P L Y L N I
Sbjct 375 LYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXXXXXXXXXX 434
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+DF L++ N++ ++ MF L L+ L LS++ S + +
Sbjct 435 XXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNSIS-QAVNG 493
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
FV L + L +L+L+ NK+ +F+ L LE LDL N + G G
Sbjct 494 SQFVPL--TSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGV---GHNLS 548
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP-----------FQPLRN 507
F L +YL L N S Q AL +S S FQ LR+
Sbjct 549 FVAQLPTLRYLSLAHNGIHSRVSQQLCSTSLWALDFSGNSLSQMWAEGDLYLRFFQGLRS 608
Query 508 LTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLH 565
L LDLS N + + L L K L++L L++N LA W L L +L
Sbjct 609 LIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSS---------LTLLPNLE 659
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L N + +L+ +D+ N++ + F L+ LNL N + +V
Sbjct 660 TLDLAGNQLKALSNGSLPSGTQLQRLDVSRNSIIFVVPGFFALATRLRELNLSANALRTV 719
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
E FG +L LD+ NP C C A FV+++ + +P L S C +P G
Sbjct 720 EPSWFGFLAGSLEVLDVSANPLHCACG--AAFVDFLLQVQAAVPGLPSRVKCGSPGQLQG 777
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 138/536 (26%), Positives = 208/536 (39%), Gaps = 105/536 (20%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE-------- 171
N+T L L+SN I + ++ F + NL L+L N GLS + +E
Sbjct 43 NVTSLSLLSNRIHHLHDSDFAQLSNLQKLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVP 102
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L+EL LS N I + + SSL L LS I + P + L L+++
Sbjct 103 TLEELNLSYNGITTVPALP------SSLVSLILSRTNILQLDPTSLTGLHALRFLYMD-- 154
Query 232 QLGPSLTEKLC---LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
G + C LE+A ++ LGL NLT L L YNNL
Sbjct 155 --GNCYYKNPCGRALEVAPGAL------------------LGLG--NLTHLSLKYNNLTT 192
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL----NLKRSFTKQSISLA--- 341
V + P LEY L YN+I L L L +R L N +R ++ +
Sbjct 193 VPR---SLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCVECPH 249
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
P++ +F L LE L ++D+ + + F GL NL L LS +F + F
Sbjct 250 KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFLYDCITKTKAF 309
Query 402 VSLAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLG---LNEIGQELTGQEW 452
LA L LNL+ N K+ + +F L L+ LD+ + Q+ T Q
Sbjct 310 QGLAQ--LRRLNLSFNYHKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQK-TLQPL 366
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV----------------- 495
L + +YL N Q F P L+ + L +
Sbjct 367 ARLPMLQRLYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXX 426
Query 496 ------------DSSPSPFQP-LRNLTI-LDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
F P +NL+ LDLS NN+ + +M L +L+ L L HN+
Sbjct 427 XXXXXXXXXXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNS 486
Query 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNN 597
+++ + L+ L +L+L N D F +L L+ +DL N+
Sbjct 487 ISQAVNGSQ-------FVPLTSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNS 535
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 96/383 (25%), Positives = 152/383 (40%), Gaps = 70/383 (18%)
Query 255 LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN---VVGNDSFAWLPQLEYFFLEYNNIQ 311
L +S + SN L LKW N LS + + ++F +P LE L YN I
Sbjct 57 LHDSDFAQLSNLQKLNLKW-NCPPAGLSPMHFPCHMTIEPNTFLAVPTLEELNLSYNGIT 115
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN------ 365
+ + L S +S ++ ++D S L L L M+ N
Sbjct 116 TVPA-------------LPSSLVSLILSRTNILQLDPTSLTGLHALRFLYMDGNCYYKNP 162
Query 366 --DIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
+ GL NL +LSL + +L T+ SL + L L+ N I +
Sbjct 163 CGRALEVAPGALLGLGNLTHLSLK--YNNLTTVPRSLPPSLEY-----LLLSYNHIVTLA 215
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
+ + L L VLD+G G R +K+ QL ++F+ + L+
Sbjct 216 PEDLANLTALRVLDVG---------GNCRRCDHARNPCVECPHKFPQLHSDTFSHLSRLE 266
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI--NDDMLEGLEKLEILDLQHN- 540
L+L+ +L ++ P F+ L NLT+LDLS N + + +GL +L L+L N
Sbjct 267 GLVLKDSSLYQLN--PRWFRGLGNLTVLDLSENFLYDCITKTKAFQGLAQLRRLNLSFNY 324
Query 541 ----NLARLWKHANPGG----------PIYF----------LKGLSHLHILNLESNGFDE 576
+ A L + G I+F L L L L L+ N ++
Sbjct 325 HKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLARLPMLQRLYLQMNFINQ 384
Query 577 IPVEVFKDLFELKIIDLGLNNLN 599
+ +FKD L+ IDL N ++
Sbjct 385 AQLGIFKDFPGLRYIDLSDNRIS 407
>5y3k_D B Toll-like receptor 9
Length=802
Score = 91.7 bits (226), Expect = 1e-17, Method: Compositional matrix adjust.
Identities = 166/660 (25%), Positives = 244/660 (37%), Gaps = 88/660 (13%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPML 101
LT VP LP ++ L L++N + L + + L LDVG N C++
Sbjct 190 LTTVPRSLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGN---------CRRCDHA 240
Query 102 K--VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
+ + H + QL TF+ + L L L +S+ ++ F NL LDLS N L
Sbjct 241 RNPCVECPH-KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFL 299
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
T+ Q L + L++L LS N K+ S
Sbjct 300 YDCITKTKA--------------FQGL----------AQLRRLNLSFNYHKKVS------ 329
Query 220 IGRLFGLFLNNVQLGPSLTEKLCL-ELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
++ L PS L L EL I SLS L + + L
Sbjct 330 --------FAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLA-------RLPMLQR 374
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L N +N F P L Y L N I
Sbjct 375 LYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXXXXXXXXXX 434
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+DF L++ N++ ++ MF L L+ L LS++ S + +
Sbjct 435 XXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNSIS-QAVNG 493
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
FV L + L +L+L+ NK+ +F+ L LE LDL N + G G
Sbjct 494 SQFVPL--TSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGV---GHNLS 548
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP-----------FQPLRN 507
F L +YL L N S Q AL +S S FQ LR+
Sbjct 549 FVAQLPTLRYLSLAHNGIHSRVSQQLCSTSLWALDFSGNSLSQMWAEGDLYLRFFQGLRS 608
Query 508 LTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLH 565
L LDLS N + + L L K L++L L++N LA W L L +L
Sbjct 609 LIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSS---------LTLLPNLE 659
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L N + +L+ +D+ N++ + F L+ LNL N + +V
Sbjct 660 TLDLAGNQLKALSNGSLPSGTQLQRLDVSRNSIIFVVPGFFALATRLRELNLSANALRTV 719
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
E FG +L LD+ NP C C A FV+++ + +P L S C +P G
Sbjct 720 EPSWFGFLAGSLEVLDVSANPLHCACG--AAFVDFLLQVQAAVPGLPSRVKCGSPGQLQG 777
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 138/536 (26%), Positives = 208/536 (39%), Gaps = 105/536 (20%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE-------- 171
N+T L L+SN I + ++ F + NL L+L N GLS + +E
Sbjct 43 NVTSLSLLSNRIHHLHDSDFAQLSNLQKLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVP 102
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L+EL LS N I + + SSL L LS I + P + L L+++
Sbjct 103 TLEELNLSYNGITTVPALP------SSLVSLILSRTNILQLDPTSLTGLHALRFLYMD-- 154
Query 232 QLGPSLTEKLC---LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
G + C LE+A ++ LGL NLT L L YNNL
Sbjct 155 --GNCYYKNPCGRALEVAPGAL------------------LGLG--NLTHLSLKYNNLTT 192
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL----NLKRSFTKQSISLA--- 341
V + P LEY L YN+I L L L +R L N +R ++ +
Sbjct 193 VPR---SLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCVECPH 249
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
P++ +F L LE L ++D+ + + F GL NL L LS +F + F
Sbjct 250 KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFLYDCITKTKAF 309
Query 402 VSLAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLG---LNEIGQELTGQEW 452
LA L LNL+ N K+ + +F L L+ LD+ + Q+ T Q
Sbjct 310 QGLAQ--LRRLNLSFNYHKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQK-TLQPL 366
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV----------------- 495
L + +YL N Q F P L+ + L +
Sbjct 367 ARLPMLQRLYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXX 426
Query 496 ------------DSSPSPFQP-LRNLTI-LDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
F P +NL+ LDLS NN+ + +M L +L+ L L HN+
Sbjct 427 XXXXXXXXXXXXXXXSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNS 486
Query 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNN 597
+++ + L+ L +L+L N D F +L L+ +DL N+
Sbjct 487 ISQAVNGSQ-------FVPLTSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNS 535
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 96/383 (25%), Positives = 152/383 (40%), Gaps = 70/383 (18%)
Query 255 LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN---VVGNDSFAWLPQLEYFFLEYNNIQ 311
L +S + SN L LKW N LS + + ++F +P LE L YN I
Sbjct 57 LHDSDFAQLSNLQKLNLKW-NCPPAGLSPMHFPCHMTIEPNTFLAVPTLEELNLSYNGIT 115
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN------ 365
+ + L S +S ++ ++D S L L L M+ N
Sbjct 116 TVPA-------------LPSSLVSLILSRTNILQLDPTSLTGLHALRFLYMDGNCYYKNP 162
Query 366 --DIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
+ GL NL +LSL + +L T+ SL + L L+ N I +
Sbjct 163 CGRALEVAPGALLGLGNLTHLSLK--YNNLTTVPRSLPPSLEY-----LLLSYNHIVTLA 215
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
+ + L L VLD+G G R +K+ QL ++F+ + L+
Sbjct 216 PEDLANLTALRVLDVG---------GNCRRCDHARNPCVECPHKFPQLHSDTFSHLSRLE 266
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI--NDDMLEGLEKLEILDLQHN- 540
L+L+ +L ++ P F+ L NLT+LDLS N + + +GL +L L+L N
Sbjct 267 GLVLKDSSLYQLN--PRWFRGLGNLTVLDLSENFLYDCITKTKAFQGLAQLRRLNLSFNY 324
Query 541 ----NLARLWKHANPGG----------PIYF----------LKGLSHLHILNLESNGFDE 576
+ A L + G I+F L L L L L+ N ++
Sbjct 325 HKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLARLPMLQRLYLQMNFINQ 384
Query 577 IPVEVFKDLFELKIIDLGLNNLN 599
+ +FKD L+ IDL N ++
Sbjct 385 AQLGIFKDFPGLRYIDLSDNRIS 407
>3wpc_A A Toll-like receptor 9
Length=802
Score = 91.7 bits (226), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 166/660 (25%), Positives = 244/660 (37%), Gaps = 88/660 (13%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPML 101
LT VP LP ++ L L++N + L + + L LDVG N C++
Sbjct 190 LTTVPRSLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGN---------CRRCDHA 240
Query 102 K--VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
+ + H + QL TF+ + L L L +S+ ++ F NL LDLS N L
Sbjct 241 RNPCVECPH-KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFL 299
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
T+ Q L + L++L LS N K+ S
Sbjct 300 YDCITKTKA--------------FQGL----------AQLRRLNLSFNYHKKVS------ 329
Query 220 IGRLFGLFLNNVQLGPSLTEKLCL-ELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM 278
++ L PS L L EL I SLS L + + L
Sbjct 330 --------FAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLA-------RLPMLQR 374
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L N +N F P L Y L N I
Sbjct 375 LYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXXXXXXXXXX 434
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+DF L++ N++ ++ MF L L+ L LS++ S + +
Sbjct 435 XXXXXXXXEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNSIS-QAVNG 493
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
FV L + L +L+L+ NK+ +F+ L LE LDL N + G G
Sbjct 494 SQFVPL--TSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGV---GHNLS 548
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP-----------FQPLRN 507
F L +YL L N S Q AL +S S FQ LR+
Sbjct 549 FVAQLPTLRYLSLAHNGIHSRVSQQLCSTSLWALDFSGNSLSQMWAEGDLYLRFFQGLRS 608
Query 508 LTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLH 565
L LDLS N + + L L K L++L L++N LA W L L +L
Sbjct 609 LIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSS---------LTLLPNLE 659
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L N + +L+ +D+ N++ + F L+ LNL N + +V
Sbjct 660 TLDLAGNQLKALSNGSLPSGTQLQRLDVSRNSIIFVVPGFFALATRLRELNLSANALRTV 719
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
E FG +L LD+ NP C C A FV+++ + +P L S C +P G
Sbjct 720 EPSWFGFLAGSLEVLDVSANPLHCACX--AAFVDFLLQVQAAVPGLPSRVKCGSPGQLQG 777
Score = 74.3 bits (181), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 139/540 (26%), Positives = 209/540 (39%), Gaps = 113/540 (21%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE-------- 171
N+T L L+SN I + ++ F + NL L+L N GLS + +E
Sbjct 43 NVTSLSLLSNRIHHLHDSDFAQLSNLQKLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVP 102
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L+EL LS N I + + SSL L LS I + P + L L+++
Sbjct 103 TLEELNLSYNGITTVPALP------SSLVSLILSRTNILQLDPTSLTGLHALRFLYMD-- 154
Query 232 QLGPSLTEKLC---LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
G + C LE+A ++ LGL NLT L L YNNL
Sbjct 155 --GNCYYKNPCGRALEVAPGAL------------------LGLG--NLTHLSLKYNNLTT 192
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL----NLKRSFTKQSISLA--- 341
V + P LEY L YN+I L L L +R L N +R ++ +
Sbjct 193 VPR---SLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCVECPH 249
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
P++ +F L LE L ++D+ + + F GL NL L LS +F + F
Sbjct 250 KFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFLYDCITKTKAF 309
Query 402 VSLAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLG---LNEIGQELTGQEW 452
LA L LNL+ N K+ + +F L L+ LD+ + Q+ T Q
Sbjct 310 QGLAQ--LRRLNLSFNYHKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQK-TLQPL 366
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV----------------- 495
L + +YL N Q F P L+ + L +
Sbjct 367 ARLPMLQRLYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEXXXXXXXXXXXXXXX 426
Query 496 -----------------DSSPSPFQPLRNLTI-LDLSNNNIANINDDMLEGLEKLEILDL 537
D PS +NL+ LDLS NN+ + +M L +L+ L L
Sbjct 427 XXXXXXXXXXXXXXXXEDFMPS----CKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRL 482
Query 538 QHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNN 597
HN++++ + L+ L +L+L N D F +L L+ +DL N+
Sbjct 483 SHNSISQAVNGSQ-------FVPLTSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNS 535
>3zyi_A A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4
Length=452
Score = 90.1 bits (222), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 87/292 (30%), Positives = 133/292 (46%), Gaps = 18/292 (6%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
LNL +N I I++D F L HLEVL LG N I Q G + GL ++ + L N +
Sbjct 80 LNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGA-FNGLASLNTLELFDNWLTVI 138
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN-NNIANINDDMLEGLE 530
+F + L+ L LR ++++ S F + +L LDL + I++ EGL
Sbjct 139 PSGAFEYLSKLRELWLRNNPIESIPS--YAFNRVPSLMRLDLGELKKLEYISEGAFEGLF 196
Query 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKI 590
L+ L+L N+ + L L L L + N F EI F L LK
Sbjct 197 NLKYLNLGMCNIKDMPN----------LTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKK 246
Query 591 IDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
+ + + ++ + + F+ SL LNL N ++S+ +F P R L EL + NP++C
Sbjct 247 LWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTP-LRYLVELHLHHNPWNCD 305
Query 651 CESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSCKDSAPF 702
C+ I W W+ E C+ P H G + D +S + SAPF
Sbjct 306 CD-ILWLAWWLREYIXXXSTCCGR--CHAPMHMRGRYLVEVDQASFQCSAPF 354
Score = 84.3 bits (207), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 78/286 (27%), Positives = 123/286 (43%), Gaps = 34/286 (12%)
Query 24 STTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVG 83
S C+ C+ L++VP +P+N LNL N ++ + A F L L +G
Sbjct 48 SVCSCSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLG 107
Query 84 FNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
N+I ++E L L L L N L+ + F + + L EL L +N I+ I + F
Sbjct 108 RNSIRQIEVGAFNGLASLNTLELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAF 167
Query 144 VKQKNLITLDLSH-NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKL 202
+ +L+ LDL L G L NL+ L L I+ + ++ L++L
Sbjct 168 NRVPSLMRLDLGELKKLEYISEGAFEGLFNLKYLNLGMCNIKDMP----NLTPLVGLEEL 223
Query 203 ELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLST 262
E+S N E PG FH + +S++ L + NSQ+S
Sbjct 224 EMSGNHFPEIRPGSFHGL---------------------------SSLKKLWVMNSQVSL 256
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
F GL +L L+L++NNL+ + +D F L L L +N
Sbjct 257 IERNAFDGL--ASLVELNLAHNNLSSLPHDLFTPLRYLVELHLHHN 300
Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 66/267 (25%), Positives = 115/267 (43%), Gaps = 41/267 (15%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
+N L+L NN+ ++ D+F L LE L N+I+ + + +GL ++ L L ++
Sbjct 75 SNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNW 134
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
L I +F++L L L + +N I I S F + +L L L
Sbjct 135 ---------LTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGE----- 180
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWR 453
K+ I AF L +L+ L+LG+ I
Sbjct 181 ----------------------LKKLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLTPLV 218
Query 454 GLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDL 513
GLE E+ +S N + ++ SF + SL++L + + ++ + F L +L L+L
Sbjct 219 GLE---ELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIER--NAFDGLASLVELNL 273
Query 514 SNNNIANINDDMLEGLEKLEILDLQHN 540
++NN++++ D+ L L L L HN
Sbjct 274 AHNNLSSLPHDLFTPLRYLVELHLHHN 300
Score = 42.4 bits (98), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 27/87 (31%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
S+ LNL N I + F+ L L+++ LG N++ + FN SL +L L N
Sbjct 75 SNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGAFNGLASLNTLELFDNW 134
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPFD 648
+T + F L EL +R NP +
Sbjct 135 LTVIPSGAF-EYLSKLRELWLRNNPIE 160
Score = 42.0 bits (97), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 35/113 (31%), Positives = 53/113 (47%), Gaps = 8/113 (7%)
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
N L+L NNI I D L LE+L L N++ ++ A GL+ L+
Sbjct 76 NTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEVGA--------FNGLASLNT 127
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQK 619
L L N IP F+ L +L+ + L N + ++P+ FN SL L+L +
Sbjct 128 LELFDNWLTVIPSGAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDLGE 180
>7cyn_B B Toll-like receptor 7
Length=1049
Score = 90.5 bits (223), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 110/397 (28%), Positives = 170/397 (43%), Gaps = 59/397 (15%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ L++ N I +KS+ F L LK L+LS + S +TL F LA L L+ + N
Sbjct 496 QTLDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNN 552
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 553 RLDLLHSTAFEELHKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV------ 597
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLE 533
LQ+LM+ + + S + LR L LD+ N + + L KLE
Sbjct 598 ----LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKLE 653
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LD+ N+L+ L G P +L L+L NG + + L L+ +DL
Sbjct 654 ELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFSWKKLQCLKNLETLDL 706
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------------ 635
N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 707 SHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTS 766
Query 636 -------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
NL L + N F CTC+++ WFV W+N T IP L++ C P + G V
Sbjct 767 FPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVNHTEVTIPYLATDVTCVGPGAHKGQSV 825
Query 689 RLFDTSSCKDSAPFELFFMINTSILLIFIFIVLLIHF 725
D +C+ + F ++ S+ L + ++ H
Sbjct 826 ISLDLYTCELDLTNLILFSLSISVSLFLMVMMTASHL 862
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 86/316 (27%), Positives = 131/316 (41%), Gaps = 55/316 (17%)
Query 343 LPKIDDFSFQWLKCLEHLNMEDNDIP---GIKSNMFTGLINLKYLSLSNSFTSLRTL--T 397
+P I SF L L ++ N +P G K+NM + +K S S T L++L
Sbjct 77 IPDISPASFHRLDHLVEIDFRCNCVPIPLGSKNNMCIKRLQIKPRSFS-GLTYLKSLYLD 135
Query 398 NETFVSLAHSPLHILNLT---KNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG 454
+ + L L N I I + + L ++E+L LG N +R
Sbjct 136 GNQLLEIPQGLPPSLQLLSLEANNIFSIRKENLTELANIEILYLGQNCY--------YRN 187
Query 455 LENIFEIYLSY----NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI 510
Y+SY + +L LT+ L+ ++LK+ + + P LT
Sbjct 188 -----PCYVSYSIEKDAFLNLTK-------------LKVLSLKDNNVTAVPTVLPSTLTE 229
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
L L NN IA I +D L +L+ILDL N R + P P +
Sbjct 230 LYLYNNMIAKIQEDDFNNLNQLQILDLS-GNCPRCYNAPFPCAPC--------------K 274
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN-LITSVEKKV 629
+N +IPV F L ELK++ L N+L +P F N L+ L+L +N L +
Sbjct 275 NNSPLQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINKLQELDLSQNFLAKEIGDAK 334
Query 630 FGPAFRNLTELDMRFN 645
F +L +LD+ FN
Sbjct 335 FLHFLPSLIQLDLSFN 350
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 43/147 (29%), Positives = 76/147 (52%), Gaps = 8/147 (5%)
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW-RGLENIFEIYL 463
A + L +L L N + + F + L+ LDL N + +E+ ++ L ++ ++ L
Sbjct 288 ALTELKVLRLHSNSLQHVPPRWFKNINKLQELDLSQNFLAKEIGDAKFLHFLPSLIQLDL 347
Query 464 SYNKYLQLTRNS------FALVPSLQRLMLRRVALKNVDS-SPSPFQPLRNLTILDLSNN 516
S+N LQ+ R S F+ + SL+ L +R K + S + SP L+NL +LDL N
Sbjct 348 SFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTN 407
Query 517 NIANINDDMLEGLEKLEILDLQHNNLA 543
I N M + ++L+++DL N ++
Sbjct 408 FIKIANLSMFKQFKRLKVIDLSVNKIS 434
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 75/262 (29%), Positives = 115/262 (44%), Gaps = 28/262 (11%)
Query 369 GIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I+ + F L LK LSL N+ T++ T+ T L L N I+KI+ D F
Sbjct 194 SIEKDAFLNLTKLKVLSLKDNNVTAVPTVLPSTLTELY--------LYNNMIAKIQEDDF 245
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY-LSYNKYLQLTRNSFALVPSLQRLM 486
+ L L++LDL +G R F N LQ+ N+F + L+ L
Sbjct 246 NNLNQLQILDL---------SGNCPRCYNAPFPCAPCKNNSPLQIPVNAFDALTELKVLR 296
Query 487 LRRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN-IND-DMLEGLEKLEILDLQHNNLAR 544
L +L++V P F+ + L LDLS N +A I D L L L LDL N +
Sbjct 297 LHSNSLQHV--PPRWFKNINKLQELDLSQNFLAKEIGDAKFLHFLPSLIQLDLSFNFELQ 354
Query 545 LWKHANPGGPIYFLKGLSHLHILNLESNGFDEIP---VEVFKDLFELKIIDLGLNNLNTL 601
+++ + + L L IL + F E+ + +L L+++DLG N +
Sbjct 355 VYRASMNLSQAF--SSLKSLKILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIA 412
Query 602 PASVFNNQVSLKSLNLQKNLIT 623
S+F LK ++L N I+
Sbjct 413 NLSMFKQFKRLKVIDLSVNKIS 434
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 81/289 (28%), Positives = 125/289 (43%), Gaps = 28/289 (10%)
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLM 131
+Y Q +LD+ N+I ++ Q L LK LNL N +SQ L+ F L L
Sbjct 493 KYGQ--TLDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFS 550
Query 132 SNSIQKIKNNPFVKQKNLITLDLSHN-------GLSSTKLGTQVQLENLQELLLSNNKIQ 184
+N + + + F + L LD+S N G++ L L+ LQ+L++++N I
Sbjct 551 NNRLDLLHSTAFEELHKLEVLDISSNSHYFQSEGITHM-LNFTKNLKVLQKLMMNDNDIS 609
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE 244
+ S ++ + SL+ LE N + R LF N ++L K L
Sbjct 610 SSTSRTME---SESLRTLEFRGNHLDVLWR---EGDNRYLQLFKNLLKLEELDISKNSLS 663
Query 245 LANTSI--------RNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW 296
+ + +NLSL+ + L + S LK NL LDLS+N L V
Sbjct 664 FLPSGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLK--NLETLDLSHNQLTTVPERLSNC 721
Query 297 LPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L+ L+ N I+ L + L F +RYL+L S Q I S P+
Sbjct 722 SRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLS-SNKIQMIQKTSFPE 769
Score = 42.7 bits (99), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 109/434 (25%), Positives = 173/434 (40%), Gaps = 64/434 (15%)
Query 31 SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL 90
+H + DC+ LT++P +PTN T L LT N + + A+F R L +D N
Sbjct 45 NHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCN----- 99
Query 91 EPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
C +P+ N+ L Q+ ++F+ T L L+L N + +I P +L
Sbjct 100 ----CVPIPLGSKNNMCIKRL-QIKPRSFSGLTYLKSLYLDGNQLLEI---PQGLPPSLQ 151
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSN-----NKIQALKSEELDIFAN-SSLKKLEL 204
L L N + S + +L N++ L L N S E D F N + LK L L
Sbjct 152 LLSLEANNIFSIRKENLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSL 211
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
N + P + L L+L N + + E L I +LS
Sbjct 212 KDNNVTAV-PTVLPST--LTELYLYNNMIA-KIQEDDFNNLNQLQILDLS---GNCPRCY 264
Query 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNV 324
N F N + L + N +F L +L+ L N++QH+ + +
Sbjct 265 NAPFPCAPCKNNSPLQIPVN--------AFDALTELKVLRLHSNSLQHVPPRWFKNINKL 316
Query 325 RYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEHLNMEDNDIPGIKSNMFT 376
+ L+L ++F + I L SL ++D F+F+ +N+ S F+
Sbjct 317 QELDLSQNFLAKEIGDAKFLHFLPSLIQLDLSFNFELQVYRASMNL---------SQAFS 367
Query 377 GLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILNLTKNKISKIESDAFSWL 430
L +LK L +R + S SPLH +L+L N I F
Sbjct 368 SLKSLKIL-------RIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIANLSMFKQF 420
Query 431 GHLEVLDLGLNEIG 444
L+V+DL +N+I
Sbjct 421 KRLKVIDLSVNKIS 434
Score = 34.7 bits (78), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 34/117 (29%), Positives = 51/117 (44%), Gaps = 2/117 (2%)
Query 43 TQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLK 102
+ V D +P N+ L+L N L+ L +LD+ N ++ + L LK
Sbjct 667 SGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLK 726
Query 103 VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHN 157
L L++N++ L+ L L L SN IQ I+ F + NL L L HN
Sbjct 727 NLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHN 783
>7cyn_A A Toll-like receptor 7
Length=1049
Score = 90.5 bits (223), Expect = 5e-17, Method: Compositional matrix adjust.
Identities = 110/397 (28%), Positives = 170/397 (43%), Gaps = 59/397 (15%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ L++ N I +KS+ F L LK L+LS + S +TL F LA L L+ + N
Sbjct 496 QTLDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNN 552
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 553 RLDLLHSTAFEELHKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV------ 597
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLE 533
LQ+LM+ + + S + LR L LD+ N + + L KLE
Sbjct 598 ----LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWREGDNRYLQLFKNLLKLE 653
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LD+ N+L+ L G P +L L+L NG + + L L+ +DL
Sbjct 654 ELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFSWKKLQCLKNLETLDL 706
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------------ 635
N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 707 SHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTS 766
Query 636 -------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
NL L + N F CTC+++ WFV W+N T IP L++ C P + G V
Sbjct 767 FPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVNHTEVTIPYLATDVTCVGPGAHKGQSV 825
Query 689 RLFDTSSCKDSAPFELFFMINTSILLIFIFIVLLIHF 725
D +C+ + F ++ S+ L + ++ H
Sbjct 826 ISLDLYTCELDLTNLILFSLSISVSLFLMVMMTASHL 862
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 86/316 (27%), Positives = 131/316 (41%), Gaps = 55/316 (17%)
Query 343 LPKIDDFSFQWLKCLEHLNMEDNDIP---GIKSNMFTGLINLKYLSLSNSFTSLRTL--T 397
+P I SF L L ++ N +P G K+NM + +K S S T L++L
Sbjct 77 IPDISPASFHRLDHLVEIDFRCNCVPIPLGSKNNMCIKRLQIKPRSFS-GLTYLKSLYLD 135
Query 398 NETFVSLAHSPLHILNLT---KNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG 454
+ + L L N I I + + L ++E+L LG N +R
Sbjct 136 GNQLLEIPQGLPPSLQLLSLEANNIFSIRKENLTELANIEILYLGQNCY--------YRN 187
Query 455 LENIFEIYLSY----NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI 510
Y+SY + +L LT+ L+ ++LK+ + + P LT
Sbjct 188 -----PCYVSYSIEKDAFLNLTK-------------LKVLSLKDNNVTAVPTVLPSTLTE 229
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
L L NN IA I +D L +L+ILDL N R + P P +
Sbjct 230 LYLYNNMIAKIQEDDFNNLNQLQILDLS-GNCPRCYNAPFPCAPC--------------K 274
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN-LITSVEKKV 629
+N +IPV F L ELK++ L N+L +P F N L+ L+L +N L +
Sbjct 275 NNSPLQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINKLQELDLSQNFLAKEIGDAK 334
Query 630 FGPAFRNLTELDMRFN 645
F +L +LD+ FN
Sbjct 335 FLHFLPSLIQLDLSFN 350
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 43/147 (29%), Positives = 76/147 (52%), Gaps = 8/147 (5%)
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW-RGLENIFEIYL 463
A + L +L L N + + F + L+ LDL N + +E+ ++ L ++ ++ L
Sbjct 288 ALTELKVLRLHSNSLQHVPPRWFKNINKLQELDLSQNFLAKEIGDAKFLHFLPSLIQLDL 347
Query 464 SYNKYLQLTRNS------FALVPSLQRLMLRRVALKNVDS-SPSPFQPLRNLTILDLSNN 516
S+N LQ+ R S F+ + SL+ L +R K + S + SP L+NL +LDL N
Sbjct 348 SFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTN 407
Query 517 NIANINDDMLEGLEKLEILDLQHNNLA 543
I N M + ++L+++DL N ++
Sbjct 408 FIKIANLSMFKQFKRLKVIDLSVNKIS 434
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 75/262 (29%), Positives = 115/262 (44%), Gaps = 28/262 (11%)
Query 369 GIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I+ + F L LK LSL N+ T++ T+ T L L N I+KI+ D F
Sbjct 194 SIEKDAFLNLTKLKVLSLKDNNVTAVPTVLPSTLTELY--------LYNNMIAKIQEDDF 245
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY-LSYNKYLQLTRNSFALVPSLQRLM 486
+ L L++LDL +G R F N LQ+ N+F + L+ L
Sbjct 246 NNLNQLQILDL---------SGNCPRCYNAPFPCAPCKNNSPLQIPVNAFDALTELKVLR 296
Query 487 LRRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN-IND-DMLEGLEKLEILDLQHNNLAR 544
L +L++V P F+ + L LDLS N +A I D L L L LDL N +
Sbjct 297 LHSNSLQHV--PPRWFKNINKLQELDLSQNFLAKEIGDAKFLHFLPSLIQLDLSFNFELQ 354
Query 545 LWKHANPGGPIYFLKGLSHLHILNLESNGFDEIP---VEVFKDLFELKIIDLGLNNLNTL 601
+++ + + L L IL + F E+ + +L L+++DLG N +
Sbjct 355 VYRASMNLSQAF--SSLKSLKILRIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIA 412
Query 602 PASVFNNQVSLKSLNLQKNLIT 623
S+F LK ++L N I+
Sbjct 413 NLSMFKQFKRLKVIDLSVNKIS 434
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 81/289 (28%), Positives = 125/289 (43%), Gaps = 28/289 (10%)
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLM 131
+Y Q +LD+ N+I ++ Q L LK LNL N +SQ L+ F L L
Sbjct 493 KYGQ--TLDLSKNSIFFVKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFS 550
Query 132 SNSIQKIKNNPFVKQKNLITLDLSHN-------GLSSTKLGTQVQLENLQELLLSNNKIQ 184
+N + + + F + L LD+S N G++ L L+ LQ+L++++N I
Sbjct 551 NNRLDLLHSTAFEELHKLEVLDISSNSHYFQSEGITHM-LNFTKNLKVLQKLMMNDNDIS 609
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE 244
+ S ++ + SL+ LE N + R LF N ++L K L
Sbjct 610 SSTSRTME---SESLRTLEFRGNHLDVLWR---EGDNRYLQLFKNLLKLEELDISKNSLS 663
Query 245 LANTSI--------RNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW 296
+ + +NLSL+ + L + S LK NL LDLS+N L V
Sbjct 664 FLPSGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLK--NLETLDLSHNQLTTVPERLSNC 721
Query 297 LPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L+ L+ N I+ L + L F +RYL+L S Q I S P+
Sbjct 722 SRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLS-SNKIQMIQKTSFPE 769
Score = 42.7 bits (99), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 109/434 (25%), Positives = 173/434 (40%), Gaps = 64/434 (15%)
Query 31 SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL 90
+H + DC+ LT++P +PTN T L LT N + + A+F R L +D N
Sbjct 45 NHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLDHLVEIDFRCN----- 99
Query 91 EPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
C +P+ N+ L Q+ ++F+ T L L+L N + +I P +L
Sbjct 100 ----CVPIPLGSKNNMCIKRL-QIKPRSFSGLTYLKSLYLDGNQLLEI---PQGLPPSLQ 151
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSN-----NKIQALKSEELDIFAN-SSLKKLEL 204
L L N + S + +L N++ L L N S E D F N + LK L L
Sbjct 152 LLSLEANNIFSIRKENLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSL 211
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
N + P + L L+L N + + E L I +LS
Sbjct 212 KDNNVTAV-PTVLPST--LTELYLYNNMIA-KIQEDDFNNLNQLQILDLS---GNCPRCY 264
Query 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNV 324
N F N + L + N +F L +L+ L N++QH+ + +
Sbjct 265 NAPFPCAPCKNNSPLQIPVN--------AFDALTELKVLRLHSNSLQHVPPRWFKNINKL 316
Query 325 RYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEHLNMEDNDIPGIKSNMFT 376
+ L+L ++F + I L SL ++D F+F+ +N+ S F+
Sbjct 317 QELDLSQNFLAKEIGDAKFLHFLPSLIQLDLSFNFELQVYRASMNL---------SQAFS 367
Query 377 GLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILNLTKNKISKIESDAFSWL 430
L +LK L +R + S SPLH +L+L N I F
Sbjct 368 SLKSLKIL-------RIRGYVFKELKSFNLSPLHNLQNLEVLDLGTNFIKIANLSMFKQF 420
Query 431 GHLEVLDLGLNEIG 444
L+V+DL +N+I
Sbjct 421 KRLKVIDLSVNKIS 434
Score = 34.7 bits (78), Expect = 6.1, Method: Compositional matrix adjust.
Identities = 34/117 (29%), Positives = 51/117 (44%), Gaps = 2/117 (2%)
Query 43 TQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLK 102
+ V D +P N+ L+L N L+ L +LD+ N ++ + L LK
Sbjct 667 SGVFDGMPPNLKNLSLAKNGLKSFSWKKLQCLKNLETLDLSHNQLTTVPERLSNCSRSLK 726
Query 103 VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHN 157
L L++N++ L+ L L L SN IQ I+ F + NL L L HN
Sbjct 727 NLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHN 783
>6lw1_B B Toll-like receptor 7
Length=823
Score = 89.4 bits (220), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 107/369 (29%), Positives = 159/369 (43%), Gaps = 59/369 (16%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ L++ N I IKS+ F L LK L+LS + S +TL F LA L L+ + N
Sbjct 474 QTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNN 530
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 531 RLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV------ 575
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLE 533
LQ+LM+ + + S + LR L LD+ + N + + L KLE
Sbjct 576 ----LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLE 631
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LD+ N+L+ L G P +L L+L NG E + L L+ +DL
Sbjct 632 ELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDL 684
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------------ 635
N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 685 SHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTS 744
Query 636 -------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
NL L + N F CTC+++ WFV W+ T IP L++ C P + G V
Sbjct 745 FPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSV 803
Query 689 RLFDTSSCK 697
D +C+
Sbjct 804 ISLDLYTCE 812
Score = 60.8 bits (146), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 87/312 (28%), Positives = 132/312 (42%), Gaps = 47/312 (15%)
Query 343 LPKIDDFSFQWLKCLEHLNMEDNDIP---GIKSNMFTGLINLKYLSLSNSFTSLRTL--T 397
+P I SF L L ++ N +P G KSNM + +K S S T L++L
Sbjct 55 IPDISPASFHRLVHLVEIDFRCNCVPIRLGSKSNMCPRRLQIKPRSFS-GLTYLKSLYLD 113
Query 398 NETFVSLAHSPLHILNLT---KNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG 454
+ + L L N I I + + L ++E+L LG N +
Sbjct 114 GNQLLEIPQGLPPSLQLLSLEANNIFSIRKEQLTELANIEILYLGQNCYYRN-------- 165
Query 455 LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLS 514
Y+SY+ + +++F + L+ L L+ NV + P+ LT L L
Sbjct 166 -----PCYVSYS----IEKDAFLNLTKLKVLSLKD---NNVTTVPTVLP--STLTELYLY 211
Query 515 NNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
NN IA I +D L +L+ILDL N R + P P ++N
Sbjct 212 NNMIAEIQEDDFNNLNQLQILDLS-GNCPRCYNAPFPCTPC--------------KNNSP 256
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN-LITSVEKKVFGPA 633
+IPV F L ELK++ L N+L +P F N +L+ L+L +N L + F
Sbjct 257 LQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHF 316
Query 634 FRNLTELDMRFN 645
NL +LD+ FN
Sbjct 317 LPNLIQLDLSFN 328
Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 44/147 (30%), Positives = 76/147 (52%), Gaps = 8/147 (5%)
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW-RGLENIFEIYL 463
A + L +L L N + + F + +L+ LDL N + +E+ ++ L N+ ++ L
Sbjct 266 ALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDL 325
Query 464 SYNKYLQLTRNS------FALVPSLQRLMLRRVALKNVDS-SPSPFQPLRNLTILDLSNN 516
S+N LQ+ R S F+ + SL+ L +R K + S SP L+NL +LDL N
Sbjct 326 SFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTN 385
Query 517 NIANINDDMLEGLEKLEILDLQHNNLA 543
I N M + ++L+++DL N ++
Sbjct 386 FIKIANLSMFKQFKRLKVIDLSVNKIS 412
Score = 50.4 bits (119), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 75/260 (29%), Positives = 113/260 (43%), Gaps = 24/260 (9%)
Query 369 GIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I+ + F L LK LSL N+ T++ T+ T L L N I++I+ D F
Sbjct 172 SIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELY--------LYNNMIAEIQEDDF 223
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY-LSYNKYLQLTRNSFALVPSLQRLM 486
+ L L++LDL +G R F N LQ+ N+F + L+ L
Sbjct 224 NNLNQLQILDL---------SGNCPRCYNAPFPCTPCKNNSPLQIPVNAFDALTELKVLR 274
Query 487 LRRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN-IND-DMLEGLEKLEILDLQHNNLAR 544
L +L++V P F+ + NL LDLS N +A I D L L L LDL N +
Sbjct 275 LHSNSLQHV--PPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQ 332
Query 545 LWKHA-NPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPA 603
+++ + N LK L L I + +L L+++DLG N +
Sbjct 333 VYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNFIKIANL 392
Query 604 SVFNNQVSLKSLNLQKNLIT 623
S+F LK ++L N I+
Sbjct 393 SMFKQFKRLKVIDLSVNKIS 412
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 125/289 (43%), Gaps = 28/289 (10%)
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLM 131
+Y Q +LD+ N+I ++ Q L LK LNL N +SQ L+ F L L
Sbjct 471 KYGQ--TLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFS 528
Query 132 SNSIQKIKNNPFVKQKNLITLDLSHN-------GLSSTKLGTQVQLENLQELLLSNNKIQ 184
+N + + + F + + L LD+S N G++ L L+ LQ+L++++N I
Sbjct 529 NNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHM-LNFTKNLKVLQKLMMNDNDIS 587
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE 244
+ S ++ + SL+ LE N + R LF N ++L K L
Sbjct 588 SSTSRTME---SESLRTLEFRGNHLDVLWRD---GDNRYLQLFKNLLKLEELDISKNSLS 641
Query 245 LANTSI--------RNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW 296
+ + +NLSL+ + L + LK NL LDLS+N L V
Sbjct 642 FLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLK--NLETLDLSHNQLTTVPERLSNC 699
Query 297 LPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L+ L+ N I+ L + L F +RYL+L S Q I S P+
Sbjct 700 SRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLS-SNKIQMIQKTSFPE 747
Score = 42.0 bits (97), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 105/451 (23%), Positives = 174/451 (39%), Gaps = 86/451 (19%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIG 444
L N I F L+V+DL +N+I
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Score = 34.7 bits (78), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 34/115 (30%), Positives = 50/115 (43%), Gaps = 2/115 (2%)
Query 45 VPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVL 104
V D +P N+ L+L N L+ L +LD+ N ++ + L LK L
Sbjct 647 VFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNL 706
Query 105 NLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHN 157
L++N++ L+ L L L SN IQ I+ F + NL L L HN
Sbjct 707 ILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHN 761
>6lw1_A A Toll-like receptor 7
Length=823
Score = 89.4 bits (220), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 107/369 (29%), Positives = 159/369 (43%), Gaps = 59/369 (16%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ L++ N I IKS+ F L LK L+LS + S +TL F LA L L+ + N
Sbjct 474 QTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNN 530
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 531 RLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV------ 575
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLE 533
LQ+LM+ + + S + LR L LD+ + N + + L KLE
Sbjct 576 ----LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLE 631
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LD+ N+L+ L G P +L L+L NG E + L L+ +DL
Sbjct 632 ELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDL 684
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------------ 635
N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 685 SHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTS 744
Query 636 -------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
NL L + N F CTC+++ WFV W+ T IP L++ C P + G V
Sbjct 745 FPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSV 803
Query 689 RLFDTSSCK 697
D +C+
Sbjct 804 ISLDLYTCE 812
Score = 60.8 bits (146), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 87/312 (28%), Positives = 132/312 (42%), Gaps = 47/312 (15%)
Query 343 LPKIDDFSFQWLKCLEHLNMEDNDIP---GIKSNMFTGLINLKYLSLSNSFTSLRTL--T 397
+P I SF L L ++ N +P G KSNM + +K S S T L++L
Sbjct 55 IPDISPASFHRLVHLVEIDFRCNCVPIRLGSKSNMCPRRLQIKPRSFS-GLTYLKSLYLD 113
Query 398 NETFVSLAHSPLHILNLT---KNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG 454
+ + L L N I I + + L ++E+L LG N +
Sbjct 114 GNQLLEIPQGLPPSLQLLSLEANNIFSIRKEQLTELANIEILYLGQNCYYRN-------- 165
Query 455 LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLS 514
Y+SY+ + +++F + L+ L L+ NV + P+ LT L L
Sbjct 166 -----PCYVSYS----IEKDAFLNLTKLKVLSLKD---NNVTTVPTVLP--STLTELYLY 211
Query 515 NNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
NN IA I +D L +L+ILDL N R + P P ++N
Sbjct 212 NNMIAEIQEDDFNNLNQLQILDLS-GNCPRCYNAPFPCTPC--------------KNNSP 256
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN-LITSVEKKVFGPA 633
+IPV F L ELK++ L N+L +P F N +L+ L+L +N L + F
Sbjct 257 LQIPVNAFDALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHF 316
Query 634 FRNLTELDMRFN 645
NL +LD+ FN
Sbjct 317 LPNLIQLDLSFN 328
Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 44/147 (30%), Positives = 76/147 (52%), Gaps = 8/147 (5%)
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW-RGLENIFEIYL 463
A + L +L L N + + F + +L+ LDL N + +E+ ++ L N+ ++ L
Sbjct 266 ALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDL 325
Query 464 SYNKYLQLTRNS------FALVPSLQRLMLRRVALKNVDS-SPSPFQPLRNLTILDLSNN 516
S+N LQ+ R S F+ + SL+ L +R K + S SP L+NL +LDL N
Sbjct 326 SFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTN 385
Query 517 NIANINDDMLEGLEKLEILDLQHNNLA 543
I N M + ++L+++DL N ++
Sbjct 386 FIKIANLSMFKQFKRLKVIDLSVNKIS 412
Score = 50.4 bits (119), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 75/260 (29%), Positives = 113/260 (43%), Gaps = 24/260 (9%)
Query 369 GIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I+ + F L LK LSL N+ T++ T+ T L L N I++I+ D F
Sbjct 172 SIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELY--------LYNNMIAEIQEDDF 223
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY-LSYNKYLQLTRNSFALVPSLQRLM 486
+ L L++LDL +G R F N LQ+ N+F + L+ L
Sbjct 224 NNLNQLQILDL---------SGNCPRCYNAPFPCTPCKNNSPLQIPVNAFDALTELKVLR 274
Query 487 LRRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN-IND-DMLEGLEKLEILDLQHNNLAR 544
L +L++V P F+ + NL LDLS N +A I D L L L LDL N +
Sbjct 275 LHSNSLQHV--PPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQ 332
Query 545 LWKHA-NPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPA 603
+++ + N LK L L I + +L L+++DLG N +
Sbjct 333 VYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNFIKIANL 392
Query 604 SVFNNQVSLKSLNLQKNLIT 623
S+F LK ++L N I+
Sbjct 393 SMFKQFKRLKVIDLSVNKIS 412
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 125/289 (43%), Gaps = 28/289 (10%)
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLM 131
+Y Q +LD+ N+I ++ Q L LK LNL N +SQ L+ F L L
Sbjct 471 KYGQ--TLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFS 528
Query 132 SNSIQKIKNNPFVKQKNLITLDLSHN-------GLSSTKLGTQVQLENLQELLLSNNKIQ 184
+N + + + F + + L LD+S N G++ L L+ LQ+L++++N I
Sbjct 529 NNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHM-LNFTKNLKVLQKLMMNDNDIS 587
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE 244
+ S ++ + SL+ LE N + R LF N ++L K L
Sbjct 588 SSTSRTME---SESLRTLEFRGNHLDVLWRD---GDNRYLQLFKNLLKLEELDISKNSLS 641
Query 245 LANTSI--------RNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW 296
+ + +NLSL+ + L + LK NL LDLS+N L V
Sbjct 642 FLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLK--NLETLDLSHNQLTTVPERLSNC 699
Query 297 LPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L+ L+ N I+ L + L F +RYL+L S Q I S P+
Sbjct 700 SRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLS-SNKIQMIQKTSFPE 747
Score = 42.0 bits (97), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 105/451 (23%), Positives = 174/451 (39%), Gaps = 86/451 (19%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIG 444
L N I F L+V+DL +N+I
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 412
Score = 34.7 bits (78), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 34/115 (30%), Positives = 50/115 (43%), Gaps = 2/115 (2%)
Query 45 VPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVL 104
V D +P N+ L+L N L+ L +LD+ N ++ + L LK L
Sbjct 647 VFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNL 706
Query 105 NLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHN 157
L++N++ L+ L L L SN IQ I+ F + NL L L HN
Sbjct 707 ILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHN 761
>8tty_A A Toll-like receptor 7
Length=817
Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 107/369 (29%), Positives = 159/369 (43%), Gaps = 59/369 (16%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ L++ N I IKS+ F L LK L+LS + S +TL F LA L L+ + N
Sbjct 474 QTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNN 530
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 531 RLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV------ 575
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLE 533
LQ+LM+ + + S + LR L LD+ + N + + L KLE
Sbjct 576 ----LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLE 631
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LD+ N+L+ L G P +L L+L NG E + L L+ +DL
Sbjct 632 ELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDL 684
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------------ 635
N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 685 SHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTS 744
Query 636 -------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
NL L + N F CTC+++ WFV W+ T IP L++ C P + G V
Sbjct 745 FPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSV 803
Query 689 RLFDTSSCK 697
D +C+
Sbjct 804 ISLDLYTCE 812
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 168/741 (23%), Positives = 275/741 (37%), Gaps = 170/741 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEI------------ 461
L N I F L+V+DL +N+I
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXXXXXL 441
Query 462 -YLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVALKN 494
Y Y+KY L L++NS + S L + N
Sbjct 442 YYFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLN 501
Query 495 VDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
+ + S FQPL L LD SNN + ++ E L KLE+LD+ N + ++
Sbjct 502 LSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHYFQ 559
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF------------------------------DEI 577
+ F K L L L + N D
Sbjct 560 SEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNR 619
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGPAF 634
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 620 YLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY---L 676
Query 635 RNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 677 KNLETLDLSHNQLTTVPERLS 697
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 125/289 (43%), Gaps = 28/289 (10%)
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLM 131
+Y Q +LD+ N+I ++ Q L LK LNL N +SQ L+ F L L
Sbjct 471 KYGQ--TLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFS 528
Query 132 SNSIQKIKNNPFVKQKNLITLDLSHN-------GLSSTKLGTQVQLENLQELLLSNNKIQ 184
+N + + + F + + L LD+S N G++ L L+ LQ+L++++N I
Sbjct 529 NNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHM-LNFTKNLKVLQKLMMNDNDIS 587
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE 244
+ S ++ + SL+ LE N + R LF N ++L K L
Sbjct 588 SSTSRTME---SESLRTLEFRGNHLDVLWRD---GDNRYLQLFKNLLKLEELDISKNSLS 641
Query 245 LANTSI--------RNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW 296
+ + +NLSL+ + L + LK NL LDLS+N L V
Sbjct 642 FLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLK--NLETLDLSHNQLTTVPERLSNC 699
Query 297 LPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L+ L+ N I+ L + L F +RYL+L S Q I S P+
Sbjct 700 SRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLS-SNKIQMIQKTSFPE 747
Score = 34.7 bits (78), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 34/115 (30%), Positives = 50/115 (43%), Gaps = 2/115 (2%)
Query 45 VPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVL 104
V D +P N+ L+L N L+ L +LD+ N ++ + L LK L
Sbjct 647 VFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNL 706
Query 105 NLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHN 157
L++N++ L+ L L L SN IQ I+ F + NL L L HN
Sbjct 707 ILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHN 761
>8s9h_A A Toll-like receptor 7
Length=817
Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 107/369 (29%), Positives = 159/369 (43%), Gaps = 59/369 (16%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ L++ N I IKS+ F L LK L+LS + S +TL F LA L L+ + N
Sbjct 474 QTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNN 530
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 531 RLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV------ 575
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLE 533
LQ+LM+ + + S + LR L LD+ + N + + L KLE
Sbjct 576 ----LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLE 631
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LD+ N+L+ L G P +L L+L NG E + L L+ +DL
Sbjct 632 ELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDL 684
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------------ 635
N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 685 SHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTS 744
Query 636 -------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
NL L + N F CTC+++ WFV W+ T IP L++ C P + G V
Sbjct 745 FPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSV 803
Query 689 RLFDTSSCK 697
D +C+
Sbjct 804 ISLDLYTCE 812
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 168/741 (23%), Positives = 275/741 (37%), Gaps = 170/741 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEI------------ 461
L N I F L+V+DL +N+I
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXXXXXL 441
Query 462 -YLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVALKN 494
Y Y+KY L L++NS + S L + N
Sbjct 442 YYFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLN 501
Query 495 VDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
+ + S FQPL L LD SNN + ++ E L KLE+LD+ N + ++
Sbjct 502 LSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHYFQ 559
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF------------------------------DEI 577
+ F K L L L + N D
Sbjct 560 SEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNR 619
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGPAF 634
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 620 YLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY---L 676
Query 635 RNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 677 KNLETLDLSHNQLTTVPERLS 697
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 125/289 (43%), Gaps = 28/289 (10%)
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLM 131
+Y Q +LD+ N+I ++ Q L LK LNL N +SQ L+ F L L
Sbjct 471 KYGQ--TLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFS 528
Query 132 SNSIQKIKNNPFVKQKNLITLDLSHN-------GLSSTKLGTQVQLENLQELLLSNNKIQ 184
+N + + + F + + L LD+S N G++ L L+ LQ+L++++N I
Sbjct 529 NNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHM-LNFTKNLKVLQKLMMNDNDIS 587
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE 244
+ S ++ + SL+ LE N + R LF N ++L K L
Sbjct 588 SSTSRTME---SESLRTLEFRGNHLDVLWRD---GDNRYLQLFKNLLKLEELDISKNSLS 641
Query 245 LANTSI--------RNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW 296
+ + +NLSL+ + L + LK NL LDLS+N L V
Sbjct 642 FLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLK--NLETLDLSHNQLTTVPERLSNC 699
Query 297 LPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L+ L+ N I+ L + L F +RYL+L S Q I S P+
Sbjct 700 SRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLS-SNKIQMIQKTSFPE 747
Score = 34.7 bits (78), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 34/115 (30%), Positives = 50/115 (43%), Gaps = 2/115 (2%)
Query 45 VPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVL 104
V D +P N+ L+L N L+ L +LD+ N ++ + L LK L
Sbjct 647 VFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNL 706
Query 105 NLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHN 157
L++N++ L+ L L L SN IQ I+ F + NL L L HN
Sbjct 707 ILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHN 761
>8s9h_B B Toll-like receptor 7
Length=817
Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 107/369 (29%), Positives = 159/369 (43%), Gaps = 59/369 (16%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ L++ N I IKS+ F L LK L+LS + S +TL F LA L L+ + N
Sbjct 474 QTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNN 530
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 531 RLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV------ 575
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLE 533
LQ+LM+ + + S + LR L LD+ + N + + L KLE
Sbjct 576 ----LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLE 631
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LD+ N+L+ L G P +L L+L NG E + L L+ +DL
Sbjct 632 ELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDL 684
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------------ 635
N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 685 SHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTS 744
Query 636 -------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
NL L + N F CTC+++ WFV W+ T IP L++ C P + G V
Sbjct 745 FPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSV 803
Query 689 RLFDTSSCK 697
D +C+
Sbjct 804 ISLDLYTCE 812
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 168/741 (23%), Positives = 275/741 (37%), Gaps = 170/741 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEI------------ 461
L N I F L+V+DL +N+I
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXXXXXL 441
Query 462 -YLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVALKN 494
Y Y+KY L L++NS + S L + N
Sbjct 442 YYFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLN 501
Query 495 VDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
+ + S FQPL L LD SNN + ++ E L KLE+LD+ N + ++
Sbjct 502 LSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHYFQ 559
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF------------------------------DEI 577
+ F K L L L + N D
Sbjct 560 SEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNR 619
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGPAF 634
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 620 YLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY---L 676
Query 635 RNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 677 KNLETLDLSHNQLTTVPERLS 697
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 125/289 (43%), Gaps = 28/289 (10%)
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLM 131
+Y Q +LD+ N+I ++ Q L LK LNL N +SQ L+ F L L
Sbjct 471 KYGQ--TLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFS 528
Query 132 SNSIQKIKNNPFVKQKNLITLDLSHN-------GLSSTKLGTQVQLENLQELLLSNNKIQ 184
+N + + + F + + L LD+S N G++ L L+ LQ+L++++N I
Sbjct 529 NNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHM-LNFTKNLKVLQKLMMNDNDIS 587
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE 244
+ S ++ + SL+ LE N + R LF N ++L K L
Sbjct 588 SSTSRTME---SESLRTLEFRGNHLDVLWRD---GDNRYLQLFKNLLKLEELDISKNSLS 641
Query 245 LANTSI--------RNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW 296
+ + +NLSL+ + L + LK NL LDLS+N L V
Sbjct 642 FLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLK--NLETLDLSHNQLTTVPERLSNC 699
Query 297 LPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L+ L+ N I+ L + L F +RYL+L S Q I S P+
Sbjct 700 SRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLS-SNKIQMIQKTSFPE 747
Score = 34.7 bits (78), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 34/115 (30%), Positives = 50/115 (43%), Gaps = 2/115 (2%)
Query 45 VPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVL 104
V D +P N+ L+L N L+ L +LD+ N ++ + L LK L
Sbjct 647 VFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNL 706
Query 105 NLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHN 157
L++N++ L+ L L L SN IQ I+ F + NL L L HN
Sbjct 707 ILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHN 761
>8tty_B B Toll-like receptor 7
Length=817
Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 107/369 (29%), Positives = 159/369 (43%), Gaps = 59/369 (16%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ L++ N I IKS+ F L LK L+LS + S +TL F LA L L+ + N
Sbjct 474 QTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNN 530
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 531 RLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV------ 575
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLE 533
LQ+LM+ + + S + LR L LD+ + N + + L KLE
Sbjct 576 ----LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLE 631
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LD+ N+L+ L G P +L L+L NG E + L L+ +DL
Sbjct 632 ELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDL 684
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------------ 635
N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 685 SHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTS 744
Query 636 -------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
NL L + N F CTC+++ WFV W+ T IP L++ C P + G V
Sbjct 745 FPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSV 803
Query 689 RLFDTSSCK 697
D +C+
Sbjct 804 ISLDLYTCE 812
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 168/741 (23%), Positives = 275/741 (37%), Gaps = 170/741 (23%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 17 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 76
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N + +++P L LK L L N+L ++ +L L L
Sbjct 77 NCVPIRLGSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 133
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 134 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 193
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 194 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 236
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 237 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 277
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 278 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 337
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 338 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 381
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEI------------ 461
L N I F L+V+DL +N+I
Sbjct 382 LGTNFIKIANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXXXXXL 441
Query 462 -YLSYNKY--------------------------LQLTRNSFALVPSLQRLMLRRVALKN 494
Y Y+KY L L++NS + S L + N
Sbjct 442 YYFRYDKYARSCXXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLN 501
Query 495 VDS-------SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
+ + S FQPL L LD SNN + ++ E L KLE+LD+ N + ++
Sbjct 502 LSGNLISQTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHYFQ 559
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF------------------------------DEI 577
+ F K L L L + N D
Sbjct 560 SEGITHMLNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNR 619
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGPAF 634
+++FK+L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK +
Sbjct 620 YLQLFKNLLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY---L 676
Query 635 RNLTELDMRFNPFDCTCESIA 655
+NL LD+ N E ++
Sbjct 677 KNLETLDLSHNQLTTVPERLS 697
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 125/289 (43%), Gaps = 28/289 (10%)
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLM 131
+Y Q +LD+ N+I ++ Q L LK LNL N +SQ L+ F L L
Sbjct 471 KYGQ--TLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFS 528
Query 132 SNSIQKIKNNPFVKQKNLITLDLSHN-------GLSSTKLGTQVQLENLQELLLSNNKIQ 184
+N + + + F + + L LD+S N G++ L L+ LQ+L++++N I
Sbjct 529 NNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHM-LNFTKNLKVLQKLMMNDNDIS 587
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE 244
+ S ++ + SL+ LE N + R LF N ++L K L
Sbjct 588 SSTSRTME---SESLRTLEFRGNHLDVLWRD---GDNRYLQLFKNLLKLEELDISKNSLS 641
Query 245 LANTSI--------RNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW 296
+ + +NLSL+ + L + LK NL LDLS+N L V
Sbjct 642 FLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLK--NLETLDLSHNQLTTVPERLSNC 699
Query 297 LPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L+ L+ N I+ L + L F +RYL+L S Q I S P+
Sbjct 700 SRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLS-SNKIQMIQKTSFPE 747
Score = 34.7 bits (78), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 34/115 (30%), Positives = 50/115 (43%), Gaps = 2/115 (2%)
Query 45 VPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVL 104
V D +P N+ L+L N L+ L +LD+ N ++ + L LK L
Sbjct 647 VFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNL 706
Query 105 NLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHN 157
L++N++ L+ L L L SN IQ I+ F + NL L L HN
Sbjct 707 ILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHN 761
>5ijd_D B Toll-like receptor 4, Variable lymphocyte receptor B
chimera
Length=594
Score = 88.6 bits (218), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 152/638 (24%), Positives = 264/638 (41%), Gaps = 93/638 (15%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL++VPDD+P++ ++L+ N L+ L + +F+ +S+L LD+ I +E +
Sbjct 14 CMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH 73
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + S +F+ T+L L + + +++ P + L L+++H
Sbjct 74 GLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAH 133
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLK--KLELSSNQIKEFS 213
N + S KL L NL + LS N IQ + +L + L++S N I
Sbjct 134 NFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQ 193
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
F I +L L L S K CL+ LA + L L L +
Sbjct 194 DQAFQGI-KLHELTLRG-NFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIM 251
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL- 327
GL + L+Y N ++++ + ++ + SL G+ +++YL
Sbjct 252 EGLCDVTIDEFRLTYTN-------------DFSDDIVKFHCLANVSAMSLAGV-SIKYLE 297
Query 328 NLKRSFTKQSISL--ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
++ + F QS+S+ L + +LK L L M I K L +L YL
Sbjct 298 DVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLT-LTMNKGSISFKK----VALPSLSYLD 352
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS + S ++ L + L L+L+ N + I S F L L+ LD + + +
Sbjct 353 LSRNALSFSGCC--SYSDLGTNSLRHLDLSFNG-AIIMSANFMGLEELQHLDFQHSTLKR 409
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+ LE + + +SY F + SL L + + K+ ++ + F
Sbjct 410 VTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKD-NTLSNVFANT 468
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT LDLS + I+ + + L +L++L++ HNNL
Sbjct 469 TNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNL----------------------- 505
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L L+S+ +++ L+ LK + L N L ++P +F+ SL+ + L
Sbjct 506 -LFLDSSHYNQ--------LYSLKELALDTNQLKSVPDGIFDRLTSLQKIWLHT------ 550
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
NP+DC+C I + W+N+
Sbjct 551 -------------------NPWDCSCPRIDYLSRWLNK 569
>5ijb_C B Toll-like receptor 4, Variable lymphocyte receptor B
chimera
Length=594
Score = 88.6 bits (218), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 152/638 (24%), Positives = 264/638 (41%), Gaps = 93/638 (15%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL++VPDD+P++ ++L+ N L+ L + +F+ +S+L LD+ I +E +
Sbjct 14 CMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH 73
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + S +F+ T+L L + + +++ P + L L+++H
Sbjct 74 GLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAH 133
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLK--KLELSSNQIKEFS 213
N + S KL L NL + LS N IQ + +L + L++S N I
Sbjct 134 NFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQ 193
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
F I +L L L S K CL+ LA + L L L +
Sbjct 194 DQAFQGI-KLHELTLRG-NFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIM 251
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL- 327
GL + L+Y N ++++ + ++ + SL G+ +++YL
Sbjct 252 EGLCDVTIDEFRLTYTN-------------DFSDDIVKFHCLANVSAMSLAGV-SIKYLE 297
Query 328 NLKRSFTKQSISL--ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
++ + F QS+S+ L + +LK L L M I K L +L YL
Sbjct 298 DVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLT-LTMNKGSISFKK----VALPSLSYLD 352
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS + S ++ L + L L+L+ N + I S F L L+ LD + + +
Sbjct 353 LSRNALSFSGCC--SYSDLGTNSLRHLDLSFNG-AIIMSANFMGLEELQHLDFQHSTLKR 409
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+ LE + + +SY F + SL L + + K+ ++ + F
Sbjct 410 VTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKD-NTLSNVFANT 468
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT LDLS + I+ + + L +L++L++ HNNL
Sbjct 469 TNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNL----------------------- 505
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L L+S+ +++ L+ LK + L N L ++P +F+ SL+ + L
Sbjct 506 -LFLDSSHYNQ--------LYSLKELALDTNQLKSVPDGIFDRLTSLQKIWLHT------ 550
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
NP+DC+C I + W+N+
Sbjct 551 -------------------NPWDCSCPRIDYLSRWLNK 569
>7mlm_A A Toll-like receptor 4,Variable lymphocyte receptor B
Length=635
Score = 88.6 bits (218), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 152/638 (24%), Positives = 264/638 (41%), Gaps = 93/638 (15%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL++VPDD+P++ ++L+ N L+ L + +F+ +S+L LD+ I +E +
Sbjct 55 CMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH 114
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + S +F+ T+L L + + +++ P + L L+++H
Sbjct 115 GLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAH 174
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLK--KLELSSNQIKEFS 213
N + S KL L NL + LS N IQ + +L + L++S N I
Sbjct 175 NFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQ 234
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
F I +L L L S K CL+ LA + L L L +
Sbjct 235 DQAFQGI-KLHELTLRG-NFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIM 292
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL- 327
GL + L+Y N ++++ + ++ + SL G+ +++YL
Sbjct 293 EGLCDVTIDEFRLTYTN-------------DFSDDIVKFHCLANVSAMSLAGV-SIKYLE 338
Query 328 NLKRSFTKQSISL--ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
++ + F QS+S+ L + +LK L L M I K L +L YL
Sbjct 339 DVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLT-LTMNKGSISFKK----VALPSLSYLD 393
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS + S ++ L + L L+L+ N + I S F L L+ LD + + +
Sbjct 394 LSRNALSFSGCC--SYSDLGTNSLRHLDLSFNG-AIIMSANFMGLEELQHLDFQHSTLKR 450
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+ LE + + +SY F + SL L + + K+ ++ + F
Sbjct 451 VTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKD-NTLSNVFANT 509
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT LDLS + I+ + + L +L++L++ HNNL
Sbjct 510 TNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNL----------------------- 546
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L L+S+ +++ L+ LK + L N L ++P +F+ SL+ + L
Sbjct 547 -LFLDSSHYNQ--------LYSLKELALDTNQLKSVPDGIFDRLTSLQKIWLHT------ 591
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
NP+DC+C I + W+N+
Sbjct 592 -------------------NPWDCSCPRIDYLSRWLNK 610
>5gmg_B B Toll-like receptor 7
Length=817
Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 107/368 (29%), Positives = 158/368 (43%), Gaps = 59/368 (16%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ L++ N I IKS+ F L LK L+LS + S +TL F LA L L+ + N
Sbjct 474 QTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNN 530
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 531 RLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV------ 575
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLE 533
LQ+LM+ + + S + LR L LD+ + N + + L KLE
Sbjct 576 ----LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLE 631
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LD+ N+L+ L G P +L L+L NG E + L L+ +DL
Sbjct 632 ELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDL 684
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------------ 635
N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 685 SHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTS 744
Query 636 -------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
NL L + N F CTC+++ WFV W+ T IP L++ C P + G V
Sbjct 745 FPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSV 803
Query 689 RLFDTSSC 696
D +C
Sbjct 804 ISLDLYTC 811
Score = 61.2 bits (147), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 167/734 (23%), Positives = 272/734 (37%), Gaps = 170/734 (23%)
Query 32 HEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS--- 88
H + DC+ LT++P +PTN T L LT N + + A+F R L +D N +
Sbjct 24 HVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRCNCVPIRL 83
Query 89 -----------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK 137
+++P L LK L L N+L ++ +L L L +N+I
Sbjct 84 GSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSLEANNIFS 140
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN- 196
I+ + N+ L L N +E L L+ K+ +LK +
Sbjct 141 IRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTV 200
Query 197 --SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLS 254
S+L +L L +N I E F+ LN +Q+ L+L+ R
Sbjct 201 LPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSGNCPR--- 240
Query 255 LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLF 314
N F N + L + N +F L +L+ L N++QH+
Sbjct 241 --------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHSNSLQHVP 284
Query 315 SHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEHLNMEDND 366
+ N++ L+L ++F + I L +L ++D F+F+ +N+
Sbjct 285 PRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRASMNL---- 340
Query 367 IPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILNLTKNKIS 420
S F+ L +LK L +R + S SPLH +L+L N I
Sbjct 341 -----SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNFIK 388
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE-------------IYLSYNK 467
F L+V+DL +N+I Y Y+K
Sbjct 389 IANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXXXXXLYYFRYDK 448
Query 468 Y--------------------------LQLTRNSFALVPSLQRLMLRRVALKNVDS---- 497
Y L L++NS + S L + N+
Sbjct 449 YARSCRXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS 508
Query 498 ---SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGP 554
+ S FQPL L LD SNN + ++ E L KLE+LD+ N + ++
Sbjct 509 QTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHYFQSEGITHM 566
Query 555 IYFLKGLSHLHILNLESNGF------------------------------DEIPVEVFKD 584
+ F K L L L + N D +++FK+
Sbjct 567 LNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 585 LFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGPAFRNLTELD 641
L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK + +NL LD
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY---LKNLETLD 683
Query 642 MRFNPFDCTCESIA 655
+ N E ++
Sbjct 684 LSHNQLTTVPERLS 697
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 125/289 (43%), Gaps = 28/289 (10%)
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLM 131
+Y Q +LD+ N+I ++ Q L LK LNL N +SQ L+ F L L
Sbjct 471 KYGQ--TLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFS 528
Query 132 SNSIQKIKNNPFVKQKNLITLDLSHN-------GLSSTKLGTQVQLENLQELLLSNNKIQ 184
+N + + + F + + L LD+S N G++ L L+ LQ+L++++N I
Sbjct 529 NNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHM-LNFTKNLKVLQKLMMNDNDIS 587
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE 244
+ S ++ + SL+ LE N + R LF N ++L K L
Sbjct 588 SSTSRTME---SESLRTLEFRGNHLDVLWRD---GDNRYLQLFKNLLKLEELDISKNSLS 641
Query 245 LANTSI--------RNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW 296
+ + +NLSL+ + L + LK NL LDLS+N L V
Sbjct 642 FLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLK--NLETLDLSHNQLTTVPERLSNC 699
Query 297 LPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L+ L+ N I+ L + L F +RYL+L S Q I S P+
Sbjct 700 SRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLS-SNKIQMIQKTSFPE 747
Score = 34.7 bits (78), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 34/115 (30%), Positives = 50/115 (43%), Gaps = 2/115 (2%)
Query 45 VPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVL 104
V D +P N+ L+L N L+ L +LD+ N ++ + L LK L
Sbjct 647 VFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNL 706
Query 105 NLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHN 157
L++N++ L+ L L L SN IQ I+ F + NL L L HN
Sbjct 707 ILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHN 761
>5gmg_A A Toll-like receptor 7
Length=817
Score = 89.0 bits (219), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 107/368 (29%), Positives = 158/368 (43%), Gaps = 59/368 (16%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ L++ N I IKS+ F L LK L+LS + S +TL F LA L L+ + N
Sbjct 474 QTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNN 530
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 531 RLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV------ 575
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLE 533
LQ+LM+ + + S + LR L LD+ + N + + L KLE
Sbjct 576 ----LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLE 631
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LD+ N+L+ L G P +L L+L NG E + L L+ +DL
Sbjct 632 ELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDL 684
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------------ 635
N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 685 SHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTS 744
Query 636 -------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
NL L + N F CTC+++ WFV W+ T IP L++ C P + G V
Sbjct 745 FPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKGQSV 803
Query 689 RLFDTSSC 696
D +C
Sbjct 804 ISLDLYTC 811
Score = 61.2 bits (147), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 167/734 (23%), Positives = 272/734 (37%), Gaps = 170/734 (23%)
Query 32 HEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS--- 88
H + DC+ LT++P +PTN T L LT N + + A+F R L +D N +
Sbjct 24 HVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRCNCVPIRL 83
Query 89 -----------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK 137
+++P L LK L L N+L ++ +L L L +N+I
Sbjct 84 GSKSNMCPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSLEANNIFS 140
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN- 196
I+ + N+ L L N +E L L+ K+ +LK +
Sbjct 141 IRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNNVTTVPTV 200
Query 197 --SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLS 254
S+L +L L +N I E F+ LN +Q+ L+L+ R
Sbjct 201 LPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSGNCPR--- 240
Query 255 LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLF 314
N F N + L + N +F L +L+ L N++QH+
Sbjct 241 --------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHSNSLQHVP 284
Query 315 SHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEHLNMEDND 366
+ N++ L+L ++F + I L +L ++D F+F+ +N+
Sbjct 285 PRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRASMNL---- 340
Query 367 IPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILNLTKNKIS 420
S F+ L +LK L +R + S SPLH +L+L N I
Sbjct 341 -----SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNFIK 388
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE-------------IYLSYNK 467
F L+V+DL +N+I Y Y+K
Sbjct 389 IANLSMFKQFKRLKVIDLSVNKISPXXXXXXXXXXXXXXXXXXXXXXXXXXXLYYFRYDK 448
Query 468 Y--------------------------LQLTRNSFALVPSLQRLMLRRVALKNVDS---- 497
Y L L++NS + S L + N+
Sbjct 449 YARSCRXXXXXXXXXXXXXSCYKYGQTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS 508
Query 498 ---SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGP 554
+ S FQPL L LD SNN + ++ E L KLE+LD+ N + ++
Sbjct 509 QTLNGSEFQPLAELRYLDFSNNRLDLLHSTAFEELRKLEVLDISSN--SHYFQSEGITHM 566
Query 555 IYFLKGLSHLHILNLESNGF------------------------------DEIPVEVFKD 584
+ F K L L L + N D +++FK+
Sbjct 567 LNFTKNLKVLQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKN 626
Query 585 LFELKIIDLGLNNLNTLPASVFNNQ-VSLKSLNLQKNLITSV--EKKVFGPAFRNLTELD 641
L +L+ +D+ N+L+ LP+ VF+ +LK+L+L KN + S EK + +NL LD
Sbjct 627 LLKLEELDISKNSLSFLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRY---LKNLETLD 683
Query 642 MRFNPFDCTCESIA 655
+ N E ++
Sbjct 684 LSHNQLTTVPERLS 697
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 125/289 (43%), Gaps = 28/289 (10%)
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLM 131
+Y Q +LD+ N+I ++ Q L LK LNL N +SQ L+ F L L
Sbjct 471 KYGQ--TLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFS 528
Query 132 SNSIQKIKNNPFVKQKNLITLDLSHN-------GLSSTKLGTQVQLENLQELLLSNNKIQ 184
+N + + + F + + L LD+S N G++ L L+ LQ+L++++N I
Sbjct 529 NNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHM-LNFTKNLKVLQKLMMNDNDIS 587
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE 244
+ S ++ + SL+ LE N + R LF N ++L K L
Sbjct 588 SSTSRTME---SESLRTLEFRGNHLDVLWRD---GDNRYLQLFKNLLKLEELDISKNSLS 641
Query 245 LANTSI--------RNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW 296
+ + +NLSL+ + L + LK NL LDLS+N L V
Sbjct 642 FLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLK--NLETLDLSHNQLTTVPERLSNC 699
Query 297 LPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L+ L+ N I+ L + L F +RYL+L S Q I S P+
Sbjct 700 SRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLS-SNKIQMIQKTSFPE 747
Score = 34.7 bits (78), Expect = 6.0, Method: Compositional matrix adjust.
Identities = 34/115 (30%), Positives = 50/115 (43%), Gaps = 2/115 (2%)
Query 45 VPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVL 104
V D +P N+ L+L N L+ L +LD+ N ++ + L LK L
Sbjct 647 VFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNL 706
Query 105 NLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHN 157
L++N++ L+ L L L SN IQ I+ F + NL L L HN
Sbjct 707 ILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHN 761
>5ijb_A A Toll-like receptor 4, Variable lymphocyte receptor B
chimera
Length=594
Score = 88.2 bits (217), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 152/638 (24%), Positives = 264/638 (41%), Gaps = 93/638 (15%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL++VPDD+P++ ++L+ N L+ L + +F+ +S+L LD+ I +E +
Sbjct 14 CMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH 73
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + S +F+ T+L L + + +++ P + L L+++H
Sbjct 74 GLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAH 133
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLK--KLELSSNQIKEFS 213
N + S KL L NL + LS N IQ + +L + L++S N I
Sbjct 134 NFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQ 193
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
F I +L L L S K CL+ LA + L L L +
Sbjct 194 DQAFQGI-KLHELTLRG-NFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIM 251
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL- 327
GL + L+Y N ++++ + ++ + SL G+ +++YL
Sbjct 252 EGLCDVTIDEFRLTYTN-------------DFSDDIVKFHCLANVSAMSLAGV-SIKYLE 297
Query 328 NLKRSFTKQSISL--ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
++ + F QS+S+ L + +LK L L M I K L +L YL
Sbjct 298 DVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLT-LTMNKGSISFKK----VALPSLSYLD 352
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS + S ++ L + L L+L+ N + I S F L L+ LD + + +
Sbjct 353 LSRNALSFSGCC--SYSDLGTNSLRHLDLSFNG-AIIMSANFMGLEELQHLDFQHSTLKR 409
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+ LE + + +SY F + SL L + + K+ ++ + F
Sbjct 410 VTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKD-NTLSNVFANT 468
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT LDLS + I+ + + L +L++L++ HNNL
Sbjct 469 TNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNL----------------------- 505
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L L+S+ +++ L+ LK + L N L ++P +F+ SL+ + L
Sbjct 506 -LFLDSSHYNQ--------LYSLKELALDTNQLKSVPDGIFDRLTSLQKIWLHT------ 550
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
NP+DC+C I + W+N+
Sbjct 551 -------------------NPWDCSCPRIDYLSRWLNK 569
>5ijd_A A Toll-like receptor 4, Variable lymphocyte receptor B
chimera
Length=594
Score = 88.2 bits (217), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 152/638 (24%), Positives = 264/638 (41%), Gaps = 93/638 (15%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL++VPDD+P++ ++L+ N L+ L + +F+ +S+L LD+ I +E +
Sbjct 14 CMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH 73
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + S +F+ T+L L + + +++ P + L L+++H
Sbjct 74 GLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAH 133
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLK--KLELSSNQIKEFS 213
N + S KL L NL + LS N IQ + +L + L++S N I
Sbjct 134 NFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQ 193
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
F I +L L L S K CL+ LA + L L L +
Sbjct 194 DQAFQGI-KLHELTLRG-NFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIM 251
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL- 327
GL + L+Y N ++++ + ++ + SL G+ +++YL
Sbjct 252 EGLCDVTIDEFRLTYTN-------------DFSDDIVKFHCLANVSAMSLAGV-SIKYLE 297
Query 328 NLKRSFTKQSISL--ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
++ + F QS+S+ L + +LK L L M I K L +L YL
Sbjct 298 DVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLT-LTMNKGSISFKK----VALPSLSYLD 352
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS + S ++ L + L L+L+ N + I S F L L+ LD + + +
Sbjct 353 LSRNALSFSGCC--SYSDLGTNSLRHLDLSFNG-AIIMSANFMGLEELQHLDFQHSTLKR 409
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+ LE + + +SY F + SL L + + K+ ++ + F
Sbjct 410 VTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKD-NTLSNVFANT 468
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT LDLS + I+ + + L +L++L++ HNNL
Sbjct 469 TNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNL----------------------- 505
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L L+S+ +++ L+ LK + L N L ++P +F+ SL+ + L
Sbjct 506 -LFLDSSHYNQ--------LYSLKELALDTNQLKSVPDGIFDRLTSLQKIWLHT------ 550
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
NP+DC+C I + W+N+
Sbjct 551 -------------------NPWDCSCPRIDYLSRWLNK 569
>4u7l_A A Leucine-rich repeats and immunoglobulin-like domains
protein 1
Length=456
Score = 87.4 bits (215), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 122/460 (27%), Positives = 204/460 (44%), Gaps = 75/460 (16%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++CT S + DC L +P DLP++ LNL++N+L
Sbjct 4 SRCTCSGDSLDCGGRGLAALPGDLPSSTRSLNLSYNKL---------------------- 41
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
S+++P + LP L+ + L +NEL+ + A +++ L L N I+ ++ +
Sbjct 42 --SEIDPAGFEDLPNLQEVYLNNNELTAVP-SLGAASSHVVSLFLQHNKIRSVEGSQLKA 98
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
+L LDLS N ++ + ++EL L+ N+I L+ D + SL L LS
Sbjct 99 YLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLELGAFD-GLSRSLLTLRLS 157
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
N+I + R F L P LT+ L L+ +++
Sbjct 158 KNRITQLPV-------RAFKL--------PRLTQ-------------LDLNRNRIRLIEG 189
Query 266 TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVR 325
TF GL +L +L L NN++ + + +F L ++ LEYN++ + S SL+GL +
Sbjct 190 LTFQGL--NSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALH 247
Query 326 YLNLKR-----------SFTKQ----SISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGI 370
L+L SF ++ +S +L ++D+ S L L L + N I I
Sbjct 248 QLHLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHI 307
Query 371 KSNMFTGLINLKYLSLS-NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
F GL +L+ L L N + T+ F L L L L NKI + AFS
Sbjct 308 AEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGL--DSLSKLTLFGNKIKSVAKRAFSG 365
Query 430 LGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
L LE L+LG N I + + + ++N+ E+++S + +L
Sbjct 366 LEGLEHLNLGGNAI-RSVQFDAFVKMKNLKELHISSDSFL 404
Score = 66.6 bits (161), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 88/328 (27%), Positives = 149/328 (45%), Gaps = 17/328 (5%)
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
+L S ++S L +ID F+ L L+ + + +N++ + S G + +SL
Sbjct 26 DLPSSTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPS---LGAASSHVVSLF 82
Query 388 NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQEL 447
+R++ A+ L +L+L+ N I+++ + F ++ L+L N IG
Sbjct 83 LQHNKIRSVEGSQLK--AYLSLEVLDLSLNNITEVRNTCFPHGPPIKELNLAGNRIGTLE 140
Query 448 TGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRN 507
G ++ + LS N+ QL +F L P L +L L R ++ ++ FQ L +
Sbjct 141 LGAFDGLSRSLLTLRLSKNRITQLPVRAFKL-PRLTQLDLNRNRIRLIEGLT--FQGLNS 197
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L +L L NNI+ + D GL K+ +L L++N+L + N G L GL+ LH L
Sbjct 198 LEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEV----NSGS----LYGLTALHQL 249
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
+L +N I + + +L + L NNL L SL L L N I+ + +
Sbjct 250 HLSNNSIARIHRKGWSFCQKLHELVLSFNNLTRLDEESLAELSSLSVLRLSHNSISHIAE 309
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIA 655
F R+L LD+ N T E +
Sbjct 310 GAF-KGLRSLRVLDLDHNEISGTIEDTS 336
>5ijc_C B Toll-like receptor 4,Variable lymphocyte receptor B
Length=635
Score = 88.2 bits (217), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 152/638 (24%), Positives = 264/638 (41%), Gaps = 93/638 (15%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL++VPDD+P++ ++L+ N L+ L + +F+ +S+L LD+ I +E +
Sbjct 55 CMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH 114
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + S +F+ T+L L + + +++ P + L L+++H
Sbjct 115 GLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAH 174
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLK--KLELSSNQIKEFS 213
N + S KL L NL + LS N IQ + +L + L++S N I
Sbjct 175 NFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQ 234
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
F I +L L L S K CL+ LA + L L L +
Sbjct 235 DQAFQGI-KLHELTLRG-NFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIM 292
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL- 327
GL + L+Y N ++++ + ++ + SL G+ +++YL
Sbjct 293 EGLCDVTIDEFRLTYTN-------------DFSDDIVKFHCLANVSAMSLAGV-SIKYLE 338
Query 328 NLKRSFTKQSISL--ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
++ + F QS+S+ L + +LK L L M I K L +L YL
Sbjct 339 DVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLT-LTMNKGSISFKK----VALPSLSYLD 393
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS + S ++ L + L L+L+ N + I S F L L+ LD + + +
Sbjct 394 LSRNALSFSGCC--SYSDLGTNSLRHLDLSFNG-AIIMSANFMGLEELQHLDFQHSTLKR 450
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+ LE + + +SY F + SL L + + K+ ++ + F
Sbjct 451 VTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKD-NTLSNVFANT 509
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT LDLS + I+ + + L +L++L++ HNNL
Sbjct 510 TNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNL----------------------- 546
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L L+S+ +++ L+ LK + L N L ++P +F+ SL+ + L
Sbjct 547 -LFLDSSHYNQ--------LYSLKELALDTNQLKSVPDGIFDRLTSLQKIWLHT------ 591
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
NP+DC+C I + W+N+
Sbjct 592 -------------------NPWDCSCPRIDYLSRWLNK 610
>3t6q_A A CD180 antigen
Length=606
Score = 88.2 bits (217), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 107/357 (30%), Positives = 162/357 (45%), Gaps = 26/357 (7%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETFVSL 404
I +F L+ L++ + + S + GL LK L LS N F +L ++ F SL
Sbjct 269 ISSNTFHCFSGLQELDLTATHLSELPSGL-VGLSTLKKLVLSANKFENLCQISASNFPSL 327
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI-GQELTGQEWRGLENIFEIYL 463
H L I TK ++ + L +L LDL ++I + + R L ++ + L
Sbjct 328 TH--LSIKGNTKRL--ELGTGCLENLENLRELDLSHDDIETSDCCNLQLRNLSHLQSLNL 383
Query 464 SYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIND 523
SYN+ L L +F P L+ L L LK V + SPFQ L L +L+LS++ + ++
Sbjct 384 SYNEPLSLKTEAFKECPQLELLDLAFTRLK-VKDAQSPFQNLHLLKVLNLSHSLLDISSE 442
Query 524 DMLEGLEKLEILDLQHNNLARLWKHANPGGPIY---FLKGLSHLHILNLESNGFDEIPVE 580
+ +GL L+ L+LQ N+ P G I L+ L L IL L I
Sbjct 443 QLFDGLPALQHLNLQGNHF--------PKGNIQKTNSLQTLGRLEILVLSFCDLSSIDQH 494
Query 581 VFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTEL 640
F L + +DL N L + ++ + LNL N I+ + + P +
Sbjct 495 AFTSLKMMNHVDLSHNRLTSSSIEALSHLKGIY-LNLASNHISIILPSLL-PILSQQRTI 552
Query 641 DMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFD-TSSC 696
++R NP DCTC +I +F+ W E + E + LC PP G VRL D T SC
Sbjct 553 NLRQNPLDCTCSNI-YFLEWYKENMQKL-EDTEDTLCENPPLLRG--VRLSDVTLSC 605
>3t6q_C B CD180 antigen
Length=606
Score = 88.2 bits (217), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 107/357 (30%), Positives = 162/357 (45%), Gaps = 26/357 (7%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETFVSL 404
I +F L+ L++ + + S + GL LK L LS N F +L ++ F SL
Sbjct 269 ISSNTFHCFSGLQELDLTATHLSELPSGL-VGLSTLKKLVLSANKFENLCQISASNFPSL 327
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI-GQELTGQEWRGLENIFEIYL 463
H L I TK ++ + L +L LDL ++I + + R L ++ + L
Sbjct 328 TH--LSIKGNTKRL--ELGTGCLENLENLRELDLSHDDIETSDCCNLQLRNLSHLQSLNL 383
Query 464 SYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIND 523
SYN+ L L +F P L+ L L LK V + SPFQ L L +L+LS++ + ++
Sbjct 384 SYNEPLSLKTEAFKECPQLELLDLAFTRLK-VKDAQSPFQNLHLLKVLNLSHSLLDISSE 442
Query 524 DMLEGLEKLEILDLQHNNLARLWKHANPGGPIY---FLKGLSHLHILNLESNGFDEIPVE 580
+ +GL L+ L+LQ N+ P G I L+ L L IL L I
Sbjct 443 QLFDGLPALQHLNLQGNHF--------PKGNIQKTNSLQTLGRLEILVLSFCDLSSIDQH 494
Query 581 VFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTEL 640
F L + +DL N L + ++ + LNL N I+ + + P +
Sbjct 495 AFTSLKMMNHVDLSHNRLTSSSIEALSHLKGIY-LNLASNHISIILPSLL-PILSQQRTI 552
Query 641 DMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFD-TSSC 696
++R NP DCTC +I +F+ W E + E + LC PP G VRL D T SC
Sbjct 553 NLRQNPLDCTCSNI-YFLEWYKENMQKL-EDTEDTLCENPPLLRG--VRLSDVTLSC 605
>6gff_I I Leucine-rich repeat-containing protein 32
Length=618
Score = 87.8 bits (216), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 170/671 (25%), Positives = 263/671 (39%), Gaps = 132/671 (20%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C + + C L L QVP LP + L+L+ NQLR + A+ Y+ L LD+ N
Sbjct 5 VPCKMVDKKVSCQVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTN 64
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
IS L+P Q L L+ L+L HN L+ M+ ++ P +
Sbjct 65 EISFLQPGAFQALTHLEHLSLAHNRLA------------------MATALSAGGLGPLPR 106
Query 146 QKNLITLDLSHNGLSSTKLGTQV-QLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
+ +LDLS N L S L + + +L L L+ N + L +L++L+L
Sbjct 107 ---VTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMP--ALEQLDL 161
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
SN + + G F + RL +L+LS + L+ S
Sbjct 162 HSNVLMDIEDGAFEGLPRL---------------------------THLNLSRNSLTCIS 194
Query 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLP-QLEYFFLEYNNIQHLFSHSLHGLFN 323
+ + L +LDLS N++ S QL + L N + H L L
Sbjct 195 DFSL-----QQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHF--PDLAALPR 247
Query 324 VRYLNLKRSFTK-QSISLASLPKIDDFSFQW----------------LKCLEHLNMEDND 366
+ YLNL + + I S W L L +L++ N+
Sbjct 248 LIYLNLSNNLIRLPXXXXXXXXXIHAPSEGWSAXXXXXXXXXXXXRPLSQLLNLDLSYNE 307
Query 367 IPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDA 426
I I + L +L +L+LS + LRT SL L +L+L+ N
Sbjct 308 IELIPDSFLEHLTSLCFLNLSRN--CLRTFEARRLGSLPC--LMLLDLSHNA-------- 355
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLM 486
LE L+LG R L ++ + L N L +FA + SLQRL
Sbjct 356 ------LETLELG------------ARALGSLRTLLLQGNALRDLPPYTFANLASLQRLN 397
Query 487 LR--RVALKNVDSSPSP-----FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
L+ RV+ P P F + +L L L +N I E L H
Sbjct 398 LQGNRVSPCGGPDEPGPSGCVAFSGITSLRSLSLVDNEI-----------ELLRAGAFLH 446
Query 540 NNLARLWKHANPGGPIY--FLKGL-SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +NPG + L GL + L +L L+ NG + V++ LK ++L N
Sbjct 447 TPLTELDLSSNPGLEVATGALGGLEASLEVLALQGNGLMVLQVDL-PCFICLKRLNLAEN 505
Query 597 NLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAW 656
L+ LPA + VSL+ L+L+ N + + G +L L ++ NP C C + W
Sbjct 506 RLSHLPA--WTQAVSLEVLDLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLSC-CGN-GW 561
Query 657 FVNWINETHTN 667
+++ +
Sbjct 562 LAAQLHQGRVD 572
>4r5d_A A Leucine rich repeat protein
Length=441
Score = 86.3 bits (212), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 76/223 (34%), Positives = 120/223 (54%), Gaps = 16/223 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T LNL++NQL LP F R + LT+L++ N ++ L + ++L L LNL +N+
Sbjct 109 TNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNQLTSLPQGVFERLTNLTTLNLSNNQ 168
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L+ L F TNLT L+L +N + + F + +L TL+LS+N L+S G +L
Sbjct 169 LTSLPQGVFERLTNLTTLNLSNNQLTSLPQGVFERLTSLTTLNLSNNQLTSLPDGVFERL 228
Query 171 ENLQELLLSNNKI--QALKSEELDIFANSSLKKLELSSNQI-----KEFSPGCFHAIGRL 223
NL+ L LSNN++ +A ++ + +SL +L LS+N I E H L
Sbjct 229 TNLKTLNLSNNQLTKEACRAVANALKQAASLHELHLSNNNIGEEGAAELVEALLHPGSTL 288
Query 224 FGLFLNNVQLGPSLTEKLCLELAN-----TSIRNLSLSNSQLS 261
L L+N +LT++ C E+A T++ L LSN+ +
Sbjct 289 ETLDLSNC----NLTKEACREIARALKQATTLHELHLSNNNIG 327
Score = 81.6 bits (200), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 74/217 (34%), Positives = 115/217 (53%), Gaps = 8/217 (4%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ LNL++NQL LP F + + LT+L++ N ++ L + ++L L LNL +N+
Sbjct 85 TNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNQ 144
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L+ L F TNLT L+L +N + + F + NL TL+LS+N L+S G +L
Sbjct 145 LTSLPQGVFERLTNLTTLNLSNNQLTSLPQGVFERLTNLTTLNLSNNQLTSLPQGVFERL 204
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI-KEFSPGCFHAI---GRLFGL 226
+L L LSNN++ +L + N LK L LS+NQ+ KE +A+ L L
Sbjct 205 TSLTTLNLSNNQLTSLPDGVFERLTN--LKTLNLSNNQLTKEACRAVANALKQAASLHEL 262
Query 227 FLNNVQLGPSLTEKLCLEL--ANTSIRNLSLSNSQLS 261
L+N +G +L L +++ L LSN L+
Sbjct 263 HLSNNNIGEEGAAELVEALLHPGSTLETLDLSNCNLT 299
Score = 70.5 bits (171), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 75/246 (30%), Positives = 108/246 (44%), Gaps = 21/246 (9%)
Query 462 YLSYNKYLQLTRNSFALVPSLQRLM-LRRVALKNVDSSPSP---FQPLRNLTILDLSNNN 517
YL +YL L N + +L+ L L + L N P F+ L NLT L+LSNN
Sbjct 61 YLPNVRYLALGGNKLHDISALKELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQ 120
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI 577
+ ++ + E L L L+L +N L L P + L++L LNL +N +
Sbjct 121 LTSLPQGVFERLASLTTLNLSNNQLTSL--------PQGVFERLTNLTTLNLSNNQLTSL 172
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNL 637
P VF+ L L ++L N L +LP VF SL +LNL N +TS+ VF NL
Sbjct 173 PQGVFERLTNLTTLNLSNNQLTSLPQGVFERLTSLTTLNLSNNQLTSLPDGVF-ERLTNL 231
Query 638 TELDMRFNPFDC-TCESIAWFVNWINETH------TNIPELSSHYLCNTPPHYHGFPVRL 690
L++ N C ++A + H NI E + L H G +
Sbjct 232 KTLNLSNNQLTKEACRAVANALKQAASLHELHLSNNNIGEEGAAELVEALLHP-GSTLET 290
Query 691 FDTSSC 696
D S+C
Sbjct 291 LDLSNC 296
Score = 63.2 bits (152), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 60/166 (36%), Positives = 89/166 (54%), Gaps = 5/166 (3%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
++L L LNL +N+L L F TNLT L+L +N + + F + +L TL+LS
Sbjct 82 KELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLS 141
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L+S G +L NL L LSNN++ +L + N L L LS+NQ+ G
Sbjct 142 NNQLTSLPQGVFERLTNLTTLNLSNNQLTSLPQGVFERLTN--LTTLNLSNNQLTSLPQG 199
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLS 261
F + L L L+N QL SL + + L N ++ L+LSN+QL+
Sbjct 200 VFERLTSLTTLNLSNNQL-TSLPDGVFERLTN--LKTLNLSNNQLT 242
Score = 62.0 bits (149), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 66/227 (29%), Positives = 103/227 (45%), Gaps = 24/227 (11%)
Query 420 SKIES-DAFSWLGHLEVLDLGLNEIG-----QELTGQEWRGLENIFEIYLSYNKYLQLTR 473
S I+S +L ++ L LG N++ +ELT W + LS N+ L +
Sbjct 51 SDIKSVQGIQYLPNVRYLALGGNKLHDISALKELTNLGW--------LNLSNNQLETLPQ 102
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
F + +L L L L ++ F+ L +LT L+LSNN + ++ + E L L
Sbjct 103 GVFEKLTNLTTLNLSNNQLTSLPQGV--FERLASLTTLNLSNNQLTSLPQGVFERLTNLT 160
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
L+L +N L L P + L++L LNL +N +P VF+ L L ++L
Sbjct 161 TLNLSNNQLTSL--------PQGVFERLTNLTTLNLSNNQLTSLPQGVFERLTSLTTLNL 212
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTEL 640
N L +LP VF +LK+LNL N +T + A + L
Sbjct 213 SNNQLTSLPDGVFERLTNLKTLNLSNNQLTKEACRAVANALKQAASL 259
Score = 56.2 bits (134), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 122/405 (30%), Positives = 182/405 (45%), Gaps = 82/405 (20%)
Query 170 LENLQELLLSNNK---IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGL 226
L N++ L L NK I ALK EL ++L L LS+NQ++ G F + L L
Sbjct 62 LPNVRYLALGGNKLHDISALK--EL-----TNLGWLNLSNNQLETLPQGVFEKLTNLTTL 114
Query 227 FLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL 286
L+N QL SL + + LA S+ L+LSN+QL++ F + TNLT L+LS
Sbjct 115 NLSNNQL-TSLPQGVFERLA--SLTTLNLSNNQLTSLPQGVFE--RLTNLTTLNLS---- 165
Query 287 NVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKI 346
N+ LPQ +F L N+ LNL + L SLP+
Sbjct 166 ----NNQLTSLPQ------------GVFER----LTNLTTLNLSNN------QLTSLPQ- 198
Query 347 DDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAH 406
F+ L L LN+ +N + + +F L NLK L+LSN+ LT E ++A+
Sbjct 199 --GVFERLTSLTTLNLSNNQLTSLPDGVFERLTNLKTLNLSNN-----QLTKEACRAVAN 251
Query 407 -----SPLHILNLTKNKIS-KIESDAFSWLGH----LEVLDLGLNEIGQELTGQEWRGLE 456
+ LH L+L+ N I + ++ L H LE LDL + +E + R L+
Sbjct 252 ALKQAASLHELHLSNNNIGEEGAAELVEALLHPGSTLETLDLSNCNLTKEACREIARALK 311
Query 457 ---NIFEIYLSYNKYLQLTRNSFALVPSL--QRLMLRRVALKNVDSSPSP----FQPLRN 507
+ E++LS N + + LV +L L + L N + + + L+
Sbjct 312 QATTLHELHLSNNNIGE--EGAAELVEALLHPGSTLETLDLSNCNLTKEACREIARALKQ 369
Query 508 LTI---LDLSNNNI-----ANINDDMLEGLEKLEILDLQHNNLAR 544
T L LSNNNI A + + +L LE LDL + NL +
Sbjct 370 ATTLHELHLSNNNIGEEGAAELVEALLHPGSTLETLDLSNCNLTK 414
>5y3m_A A Toll-like receptor 9
Length=801
Score = 87.0 bits (214), Expect = 5e-16, Method: Compositional matrix adjust.
Identities = 97/342 (28%), Positives = 144/342 (42%), Gaps = 36/342 (11%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L++ N++ I+ MFT L L+ L LS++ S + + FV L + L +L+L+ NK+
Sbjct 455 LDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSIS-QAVNGSQFVPL--TSLRVLDLSHNKL 511
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALV 479
+F+ L LE LDL N + G G F L +YL L N +
Sbjct 512 DLYHGRSFTELPQLEALDLSYNSQPFSMQGV---GHNLSFVAQLPSLRYLSLAHNG---I 565
Query 480 PSLQRLMLRRVALKNVDSSPSP--------------FQPLRNLTILDLSNNNIANINDDM 525
S L +L+ +D S + F+ LRNL LDLS N++ +
Sbjct 566 HSRVSQKLSSASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLDLSENHLHTLLPRH 625
Query 526 LEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFK 583
L+ L K L L L+ NNLA W L L L L+L N +
Sbjct 626 LDNLPKSLRQLRLRDNNLAFFNWSS---------LTVLPRLEALDLAGNQLKALSNGSLP 676
Query 584 DLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMR 643
L+ +D+ N++ + F L LNL N + +V+ FG L LD+
Sbjct 677 PGIRLQKLDVSSNSIGFVIPGFFVRATRLIELNLSANALKTVDPSWFGSLAGTLKILDVS 736
Query 644 FNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
NP C C A FV+++ E +P LS C +P G
Sbjct 737 ANPLHCACG--AAFVDFLLERQEAVPGLSRRVTCGSPGQLQG 776
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 87/327 (27%), Positives = 137/327 (42%), Gaps = 39/327 (12%)
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLMSNSIQK 137
+LD+ N + ++ E+ +L L+ L L HN +SQ ++ F T+L L L N +
Sbjct 454 TLDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSISQAVNGSQFVPLTSLRVLDLSHNKLDL 513
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQ------VQLENLQELLLSNNKIQALKSEEL 191
F + L LDLS+N + G QL +L+ L L++N I + S++L
Sbjct 514 YHGRSFTELPQLEALDLSYNSQPFSMQGVGHNLSFVAQLPSLRYLSLAHNGIHSRVSQKL 573
Query 192 DIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL----NNVQLGPSLTEKLCLELAN 247
+++SL+ L+ S N + + A G L+ F N VQL L+E L
Sbjct 574 ---SSASLRALDFSGNSLSQ-----MWAEGDLYLCFFKGLRNLVQL--DLSENHLHTLLP 623
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM------LDLSYNNLNVVGNDSFAWLPQLE 301
+ NL S QL N W++LT+ LDL+ N L + N S +L+
Sbjct 624 RHLDNLPKSLRQLRLRDNNLAF-FNWSSLTVLPRLEALDLAGNQLKALSNGSLPPGIRLQ 682
Query 302 YFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQS-----ISLASLPKIDDFSFQWLKC 356
+ N+I + + LNL + K SLA KI D S L C
Sbjct 683 KLDVSSNSIGFVIPGFFVRATRLIELNLSANALKTVDPSWFGSLAGTLKILDVSANPLHC 742
Query 357 ------LEHLNMEDNDIPGIKSNMFTG 377
++ L +PG+ + G
Sbjct 743 ACGAAFVDFLLERQEAVPGLSRRVTCG 769
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 73/264 (28%), Positives = 123/264 (47%), Gaps = 32/264 (12%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP----------ELCQKLPM 100
T++ VL+L+HN+L +FT QL +LD+ +N+ +P +LP
Sbjct 499 TSLRVLDLSHNKLDLYHGRSFTELPQLEALDLSYNS----QPFSMQGVGHNLSFVAQLPS 554
Query 101 LKVLNLQHNEL-SQLSDKTFAFCTNLTELHLMSNSIQKIKNNP------FVKQKNLITLD 153
L+ L+L HN + S++S K + +L L NS+ ++ F +NL+ LD
Sbjct 555 LRYLSLAHNGIHSRVSQKLSS--ASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLD 612
Query 154 LSHNGLSSTKLGTQVQ--LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
LS N L T L + ++L++L L +N + L + L+ L+L+ NQ+K
Sbjct 613 LSENHL-HTLLPRHLDNLPKSLRQLRLRDNNLAFFNWSSLTVLPR--LEALDLAGNQLKA 669
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
S G RL L +++ +G + + T + L+LS + L T + F L
Sbjct 670 LSNGSLPPGIRLQKLDVSSNSIGFVIPG---FFVRATRLIELNLSANALKTVDPSWFGSL 726
Query 272 KWTNLTMLDLSYNNLNVVGNDSFA 295
T L +LD+S N L+ +F
Sbjct 727 AGT-LKILDVSANPLHCACGAAFV 749
Score = 51.2 bits (121), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 153/579 (26%), Positives = 221/579 (38%), Gaps = 134/579 (23%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN---------------- 85
LT+VP LP ++ L L++N + L + + L LDVG N
Sbjct 190 LTEVPRRLPPSLDTLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCRECPK 249
Query 86 ------------------------TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAF 121
++ KLE + + L L+VL+L N L KT F
Sbjct 250 NFPKLHPDTFSHLSRLEGLVLKDSSLYKLEKDWFRGLGRLQVLDLSENFLYDYITKTTIF 309
Query 122 --CTNLTELHLMSNSIQKIK------NNPFVKQKNLITLDLSH---NGLSSTKLGTQVQL 170
T L L+L N +K+ + F +L LD+ L++ L + +L
Sbjct 310 NDLTQLRRLNLSFNYHKKVSFAHLHLASSFGSLVSLEKLDMHGIFFRSLTNITLQSLTRL 369
Query 171 ENLQELLLSNNKIQALKSEELDIF-ANSSLKKLELSSNQIKEFS---------------- 213
LQ L L N I +L IF A SL ++LS N+I
Sbjct 370 PKLQSLHLQLNFI---NQAQLSIFGAFPSLLFVDLSDNRISGAXXXXXXXXXXXXXXXXX 426
Query 214 --------------------PGCFHAIGRLFGLFLNNV-----QLGPSLTEKLCLELANT 248
P C + L NN+ ++ L+ CL L++
Sbjct 427 XXXXXXXXXXXXXXXXXXXMPSC--NLNFTLDLSRNNLVTIQQEMFTRLSRLQCLRLSHN 484
Query 249 SIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
SI +++ SQ + T+L +LDLS+N L++ SF LPQLE L YN
Sbjct 485 SISQ-AVNGSQF----------VPLTSLRVLDLSHNKLDLYHGRSFTELPQLEALDLSYN 533
Query 309 NIQHLFSHSLHGLF------NVRYLNLK----RSFTKQSISLASLPKIDDFSFQWLKCLE 358
+ H L ++RYL+L S Q +S ASL + DFS L +
Sbjct 534 SQPFSMQGVGHNLSFVAQLPSLRYLSLAHNGIHSRVSQKLSSASLRAL-DFSGNSLSQM- 591
Query 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
+ D + F GL NL L LS + L TL +L S L L L N
Sbjct 592 ---WAEGD---LYLCFFKGLRNLVQLDLSEN--HLHTLLPRHLDNLPKS-LRQLRLRDNN 642
Query 419 ISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFAL 478
++ + + L LE LDL N++ G G+ + ++ +S N + F
Sbjct 643 LAFFNWSSLTVLPRLEALDLAGNQLKALSNGSLPPGIR-LQKLDVSSNSIGFVIPGFFVR 701
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRN-LTILDLSNN 516
L L L ALK VD PS F L L ILD+S N
Sbjct 702 ATRLIELNLSANALKTVD--PSWFGSLAGTLKILDVSAN 738
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 115/423 (27%), Positives = 167/423 (39%), Gaps = 81/423 (19%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE------- 171
N+T L L+SN I + ++ FV NL L+L N GLS ++ +E
Sbjct 42 ANVTSLSLISNRIHHLHDSDFVHLSNLRVLNLKWNCPPAGLSPMHFPCRMTIEPNTFLAV 101
Query 172 -NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L+EL LS N I + + SSL L LS I P F + L L+++
Sbjct 102 PTLEELNLSYNGITTVPALP------SSLVSLSLSHTSILVLGPTHFTGLHALRFLYMDG 155
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
C + N R L ++ L LGL NLT L L YNNL V
Sbjct 156 N----------CYYM-NPCPRALEVAPGAL--------LGLG--NLTHLSLKYNNLTEVP 194
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL-------ASL 343
P L+ L YN+I L L L +R L++ + + + +
Sbjct 195 RR---LPPSLDTLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCRECPKNF 251
Query 344 PKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS 403
PK+ +F L LE L ++D+ + ++ + F GL L+ L LS +F F
Sbjct 252 PKLHPDTFSHLSRLEGLVLKDSSLYKLEKDWFRGLGRLQVLDLSENFLYDYITKTTIFND 311
Query 404 LAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN 457
L L LNL+ N K+ + +F L LE LD + G +R L N
Sbjct 312 LTQ--LRRLNLSFNYHKKVSFAHLHLASSFGSLVSLEKLD---------MHGIFFRSLTN 360
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
I T S +P LQ L L+ + S F +L +DLS+N
Sbjct 361 I-------------TLQSLTRLPKLQSLHLQLNFINQAQL--SIFGAFPSLLFVDLSDNR 405
Query 518 IAN 520
I+
Sbjct 406 ISG 408
Score = 40.4 bits (93), Expect = 0.10, Method: Compositional matrix adjust.
Identities = 153/685 (22%), Positives = 248/685 (36%), Gaps = 158/685 (23%)
Query 32 HEVADCSHLKLTQVP---DDLP-TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
H DC+ L L VP P N+T L+L N++ L ++F S L
Sbjct 19 HGQVDCNWLFLKSVPHFSAGAPRANVTSLSLISNRIHHLHDSDFVHLSNL---------- 68
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFC--TNLTELHLMSNSIQKIKNNPFVK 145
+VLNL+ N C L+ +H I+ N F+
Sbjct 69 --------------RVLNLKWN------------CPPAGLSPMHFPCR--MTIEPNTFLA 100
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQE----LLLSNNKIQALKSEELDIFANSSLKK 201
L L+LS+NG+++ + L+L L + ++ + +
Sbjct 101 VPTLEELNLSYNGITTVPALPSSLVSLSLSHTSILVLGPTHFTGLHALRF-LYMDGNCYY 159
Query 202 LELSSNQIKEFSPGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
+ + E +PG +G L L L NN+ P S+ L LS +
Sbjct 160 MNPCPRAL-EVAPGALLGLGNLTHLSLKYNNLTEVPRRLPP--------SLDTLLLSYNH 210
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYN----------------NLNVVGNDSFAWLPQLEYF 303
+ T + L T L +LD+ N N + D+F+ L +LE
Sbjct 211 IVTLAPEDLANL--TALRVLDVGGNCRRCDHARNPCRECPKNFPKLHPDTFSHLSRLEGL 268
Query 304 FLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNME 363
L+ +++ L GL ++ L+L +F I+ ++ F L L LN+
Sbjct 269 VLKDSSLYKLEKDWFRGLGRLQVLDLSENFLYDYITKTTI-------FNDLTQLRRLNLS 321
Query 364 DNDIPGIK------SNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILNLTK 416
N + ++ F L++L+ L + F R+LTN T SL P L L+L
Sbjct 322 FNYHKKVSFAHLHLASSFGSLVSLEKLDMHGIF--FRSLTNITLQSLTRLPKLQSLHLQL 379
Query 417 NKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI------------------ 458
N I++ + F L +DL N I
Sbjct 380 NFINQAQLSIFGAFPSLLFVDLSDNRISGAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 439
Query 459 -------------FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
F + LS N + + + F + LQ L L ++ + S F PL
Sbjct 440 XXXXXXMPSCNLNFTLDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSISQAVNG-SQFVPL 498
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
+L +LDLS+N + + L +LE LDL +N ++ + G + F+ L L
Sbjct 499 TSLRVLDLSHNKLDLYHGRSFTELPQLEALDLSYN--SQPFSMQGVGHNLSFVAQLPSLR 556
Query 566 ILNLESNGF-----------------------------DEIPVEVFKDLFELKIIDLGLN 596
L+L NG ++ + FK L L +DL N
Sbjct 557 YLSLAHNGIHSRVSQKLSSASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLDLSEN 616
Query 597 NLNT-LPASVFNNQVSLKSLNLQKN 620
+L+T LP + N SL+ L L+ N
Sbjct 617 HLHTLLPRHLDNLPKSLRQLRLRDN 641
>3zyn_A A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B
Length=321
Score = 83.2 bits (204), Expect = 8e-16, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 127/289 (44%), Gaps = 34/289 (12%)
Query 22 ASSTTKCTVSHEVAD--CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTS 79
S C+ S++ + C+ +L +VP +P N LNL N ++ + F L
Sbjct 4 TSCPAACSCSNQASRVICTRRELAEVPASIPVNTRYLNLQENSIQVIRTDTFKHLRHLEI 63
Query 80 LDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
L + N + K+E LP L L L N L+ + + F + + L EL L +N I+ I
Sbjct 64 LQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIP 123
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
+ F + +L LDL L + ++ E L L N + LK ++ A L
Sbjct 124 SYAFNRVPSLRRLDLGE--LKRLEYISEAAFEGLVNLRYLNLGMCNLKDIP-NLTALVRL 180
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
++LELS N++ PG F + TS+R L L ++Q
Sbjct 181 EELELSGNRLDLIRPGSFQGL---------------------------TSLRKLWLMHAQ 213
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
++T F LK +L L+LS+NNL + +D F L +LE L +N
Sbjct 214 VATIERNAFDDLK--SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 260
Score = 77.8 bits (190), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 94/319 (29%), Positives = 143/319 (45%), Gaps = 50/319 (16%)
Query 379 INLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
+N +YL+L NS +RT +TF L H L IL L+KN + KIE AF+ L L L+
Sbjct 35 VNTRYLNLQENSIQVIRT---DTFKHLRH--LEILQLSKNLVRKIEVGAFNGLPSLNTLE 89
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS 497
L N + T Q + L + E++L N + +F VPSL+RL L LK ++
Sbjct 90 LFDNRLTTVPT-QAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGE--LKRLEY 146
Query 498 -SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY 556
S + F+ L NL L+L N+ +I + L L +LE L+L N L
Sbjct 147 ISEAAFEGLVNLRYLNLGMCNLKDIPN--LTALVRLEELELSGNRL-------------- 190
Query 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
D I F+ L L+ + L + T+ + F++ SL+ LN
Sbjct 191 ------------------DLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELN 232
Query 617 LQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPE-LSSHY 675
L N + S+ +F P R L + + NP+ C C+ + W W+ ET +P +
Sbjct 233 LSHNNLMSLPHDLFTPLHR-LERVHLNHNPWHCNCD-VLWLSWWLKET---VPSNTTCCA 287
Query 676 LCNTPPHYHGFPVRLFDTS 694
C+ P G + D S
Sbjct 288 RCHAPAGLKGRYIGELDQS 306
Score = 58.9 bits (141), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 71/231 (31%), Positives = 107/231 (46%), Gaps = 33/231 (14%)
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
N RYLNL+ + S+ I +F+ L+ LE L + N + I+ F GL +L
Sbjct 36 NTRYLNLQEN---------SIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLN 86
Query 383 YLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE 442
L L ++ L T+ + F L S L L L N I I S AF+ + L LDLG +
Sbjct 87 TLELFDN--RLTTVPTQAFEYL--SKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELK 142
Query 443 IGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS---- 498
+ ++ + GL N+ +YL L + +P+L L V L+ ++ S
Sbjct 143 RLEYISEAAFEGLVNL--------RYLNLGMCNLKDIPNLTAL----VRLEELELSGNRL 190
Query 499 ----PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
P FQ L +L L L + +A I + + L+ LE L+L HNNL L
Sbjct 191 DLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSL 241
Score = 53.5 bits (127), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 70/278 (25%), Positives = 119/278 (43%), Gaps = 43/278 (15%)
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
+L++ + N L+L NSIQ I+ + F ++L L LS N + ++G L +
Sbjct 25 ELAEVPASIPVNTRYLNLQENSIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPS 84
Query 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ 232
L L L +N++ + ++ + S L++L L +N I+ F+ +
Sbjct 85 LNTLELFDNRLTTVPTQAFEYL--SKLRELWLRNNPIESIPSYAFNRV------------ 130
Query 233 LGPSLTEKLCLELANTSIRNLSLSN-SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGN 291
S+R L L +L S F GL NL L+L NL + N
Sbjct 131 ---------------PSLRRLDLGELKRLEYISEAAFEGL--VNLRYLNLGMCNLKDIPN 173
Query 292 DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSF 351
L +LE L N + + S GL ++R L L A + I+ +F
Sbjct 174 --LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMH---------AQVATIERNAF 222
Query 352 QWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
LK LE LN+ N++ + ++FT L L+ + L+++
Sbjct 223 DDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 260
Score = 51.6 bits (122), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 66/269 (25%), Positives = 115/269 (43%), Gaps = 45/269 (17%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
N L+L N++ V+ D+F L LE L N ++ + + +GL ++ L L F
Sbjct 35 VNTRYLNLQENSIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLEL---F 91
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
+ L + +F++L L L + +N I I S F + +L+ L L
Sbjct 92 DNR------LTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGE----- 140
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ--ELTGQE 451
++ I AF L +L L+LG+ + LT
Sbjct 141 ----------------------LKRLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLT--- 175
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
L + E+ LS N+ + SF + SL++L L + ++ + F L++L L
Sbjct 176 --ALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIER--NAFDDLKSLEEL 231
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHN 540
+LS+NN+ ++ D+ L +LE + L HN
Sbjct 232 NLSHNNLMSLPHDLFTPLHRLERVHLNHN 260
>3zyn_B B LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B
Length=321
Score = 83.2 bits (204), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 127/289 (44%), Gaps = 34/289 (12%)
Query 22 ASSTTKCTVSHEVAD--CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTS 79
S C+ S++ + C+ +L +VP +P N LNL N ++ + F L
Sbjct 4 TSCPAACSCSNQASRVICTRRELAEVPASIPVNTRYLNLQENSIQVIRTDTFKHLRHLEI 63
Query 80 LDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
L + N + K+E LP L L L N L+ + + F + + L EL L +N I+ I
Sbjct 64 LQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIP 123
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
+ F + +L LDL L + ++ E L L N + LK ++ A L
Sbjct 124 SYAFNRVPSLRRLDLGE--LKRLEYISEAAFEGLVNLRYLNLGMCNLKDIP-NLTALVRL 180
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
++LELS N++ PG F + TS+R L L ++Q
Sbjct 181 EELELSGNRLDLIRPGSFQGL---------------------------TSLRKLWLMHAQ 213
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
++T F LK +L L+LS+NNL + +D F L +LE L +N
Sbjct 214 VATIERNAFDDLK--SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 260
Score = 77.8 bits (190), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 94/319 (29%), Positives = 143/319 (45%), Gaps = 50/319 (16%)
Query 379 INLKYLSLS-NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
+N +YL+L NS +RT +TF L H L IL L+KN + KIE AF+ L L L+
Sbjct 35 VNTRYLNLQENSIQVIRT---DTFKHLRH--LEILQLSKNLVRKIEVGAFNGLPSLNTLE 89
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS 497
L N + T Q + L + E++L N + +F VPSL+RL L LK ++
Sbjct 90 LFDNRLTTVPT-QAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGE--LKRLEY 146
Query 498 -SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY 556
S + F+ L NL L+L N+ +I + L L +LE L+L N L
Sbjct 147 ISEAAFEGLVNLRYLNLGMCNLKDIPN--LTALVRLEELELSGNRL-------------- 190
Query 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
D I F+ L L+ + L + T+ + F++ SL+ LN
Sbjct 191 ------------------DLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELN 232
Query 617 LQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPE-LSSHY 675
L N + S+ +F P R L + + NP+ C C+ + W W+ ET +P +
Sbjct 233 LSHNNLMSLPHDLFTPLHR-LERVHLNHNPWHCNCD-VLWLSWWLKET---VPSNTTCCA 287
Query 676 LCNTPPHYHGFPVRLFDTS 694
C+ P G + D S
Sbjct 288 RCHAPAGLKGRYIGELDQS 306
Score = 58.5 bits (140), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 71/231 (31%), Positives = 107/231 (46%), Gaps = 33/231 (14%)
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
N RYLNL+ + S+ I +F+ L+ LE L + N + I+ F GL +L
Sbjct 36 NTRYLNLQEN---------SIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLN 86
Query 383 YLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE 442
L L ++ L T+ + F L S L L L N I I S AF+ + L LDLG +
Sbjct 87 TLELFDN--RLTTVPTQAFEYL--SKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELK 142
Query 443 IGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS---- 498
+ ++ + GL N+ +YL L + +P+L L V L+ ++ S
Sbjct 143 RLEYISEAAFEGLVNL--------RYLNLGMCNLKDIPNLTAL----VRLEELELSGNRL 190
Query 499 ----PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
P FQ L +L L L + +A I + + L+ LE L+L HNNL L
Sbjct 191 DLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSL 241
Score = 53.1 bits (126), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 70/278 (25%), Positives = 119/278 (43%), Gaps = 43/278 (15%)
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
+L++ + N L+L NSIQ I+ + F ++L L LS N + ++G L +
Sbjct 25 ELAEVPASIPVNTRYLNLQENSIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPS 84
Query 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ 232
L L L +N++ + ++ + S L++L L +N I+ F+ +
Sbjct 85 LNTLELFDNRLTTVPTQAFEYL--SKLRELWLRNNPIESIPSYAFNRV------------ 130
Query 233 LGPSLTEKLCLELANTSIRNLSLSN-SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGN 291
S+R L L +L S F GL NL L+L NL + N
Sbjct 131 ---------------PSLRRLDLGELKRLEYISEAAFEGL--VNLRYLNLGMCNLKDIPN 173
Query 292 DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSF 351
L +LE L N + + S GL ++R L L A + I+ +F
Sbjct 174 --LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMH---------AQVATIERNAF 222
Query 352 QWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
LK LE LN+ N++ + ++FT L L+ + L+++
Sbjct 223 DDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 260
Score = 51.6 bits (122), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 66/269 (25%), Positives = 115/269 (43%), Gaps = 45/269 (17%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
N L+L N++ V+ D+F L LE L N ++ + + +GL ++ L L F
Sbjct 35 VNTRYLNLQENSIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLEL---F 91
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
+ L + +F++L L L + +N I I S F + +L+ L L
Sbjct 92 DNR------LTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGE----- 140
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ--ELTGQE 451
++ I AF L +L L+LG+ + LT
Sbjct 141 ----------------------LKRLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLT--- 175
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
L + E+ LS N+ + SF + SL++L L + ++ + F L++L L
Sbjct 176 --ALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIER--NAFDDLKSLEEL 231
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHN 540
+LS+NN+ ++ D+ L +LE + L HN
Sbjct 232 NLSHNNLMSLPHDLFTPLHRLERVHLNHN 260
>7ytp_A A Toll-like receptor 7
Length=975
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 104/357 (29%), Positives = 154/357 (43%), Gaps = 59/357 (17%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ L++ N I IKS+ F L LK L+LS + S +TL F LA L L+ + N
Sbjct 492 QTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNN 548
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 549 RLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV------ 593
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLE 533
LQ+LM+ + + S + LR L LD+ + N + + L KLE
Sbjct 594 ----LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLE 649
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LD+ N+L+ L G P +L L+L NG E + L L+ +DL
Sbjct 650 ELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDL 702
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------------ 635
N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 703 SHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTS 762
Query 636 -------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
NL L + N F CTC+++ WFV W+ T IP L++ C P + G
Sbjct 763 FPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKG 818
Score = 57.0 bits (136), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 67/230 (29%), Positives = 102/230 (44%), Gaps = 38/230 (17%)
Query 417 NKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSF 476
N I I + + L ++E+L LG N +R Y+SY+ + +++F
Sbjct 154 NNIFSIRKEQLTELANIEILYLGQNCY--------YRN-----PCYVSYS----IEKDAF 196
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILD 536
+ L+ L L+ NV + P+ LT L L NN IA I +D L +L+ILD
Sbjct 197 LNLTKLKVLSLKD---NNVTTVPTVLP--STLTELYLYNNMIAEIQEDDFNNLNQLQILD 251
Query 537 LQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L N R + P P ++N +IPV F L ELK++ L N
Sbjct 252 LS-GNCPRCYNAPFPCTPC--------------KNNSPLQIPVNAFDALTELKVLRLHSN 296
Query 597 NLNTLPASVFNNQVSLKSLNLQKN-LITSVEKKVFGPAFRNLTELDMRFN 645
+L +P F N +L+ L+L +N L + F NL +LD+ FN
Sbjct 297 SLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFN 346
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 44/147 (30%), Positives = 76/147 (52%), Gaps = 8/147 (5%)
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW-RGLENIFEIYL 463
A + L +L L N + + F + +L+ LDL N + +E+ ++ L N+ ++ L
Sbjct 284 ALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDL 343
Query 464 SYNKYLQLTRNS------FALVPSLQRLMLRRVALKNVDS-SPSPFQPLRNLTILDLSNN 516
S+N LQ+ R S F+ + SL+ L +R K + S SP L+NL +LDL N
Sbjct 344 SFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTN 403
Query 517 NIANINDDMLEGLEKLEILDLQHNNLA 543
I N M + ++L+++DL N ++
Sbjct 404 FIKIANLSMFKQFKRLKVIDLSVNKIS 430
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 75/260 (29%), Positives = 113/260 (43%), Gaps = 24/260 (9%)
Query 369 GIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I+ + F L LK LSL N+ T++ T+ T L L N I++I+ D F
Sbjct 190 SIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELY--------LYNNMIAEIQEDDF 241
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY-LSYNKYLQLTRNSFALVPSLQRLM 486
+ L L++LDL +G R F N LQ+ N+F + L+ L
Sbjct 242 NNLNQLQILDL---------SGNCPRCYNAPFPCTPCKNNSPLQIPVNAFDALTELKVLR 292
Query 487 LRRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN-IND-DMLEGLEKLEILDLQHNNLAR 544
L +L++V P F+ + NL LDLS N +A I D L L L LDL N +
Sbjct 293 LHSNSLQHV--PPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQ 350
Query 545 LWKHA-NPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPA 603
+++ + N LK L L I + +L L+++DLG N +
Sbjct 351 VYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNFIKIANL 410
Query 604 SVFNNQVSLKSLNLQKNLIT 623
S+F LK ++L N I+
Sbjct 411 SMFKQFKRLKVIDLSVNKIS 430
Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 125/289 (43%), Gaps = 28/289 (10%)
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLM 131
+Y Q +LD+ N+I ++ Q L LK LNL N +SQ L+ F L L
Sbjct 489 KYGQ--TLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFS 546
Query 132 SNSIQKIKNNPFVKQKNLITLDLSHN-------GLSSTKLGTQVQLENLQELLLSNNKIQ 184
+N + + + F + + L LD+S N G++ L L+ LQ+L++++N I
Sbjct 547 NNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHM-LNFTKNLKVLQKLMMNDNDIS 605
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE 244
+ S ++ + SL+ LE N + R LF N ++L K L
Sbjct 606 SSTSRTME---SESLRTLEFRGNHLDVLWRD---GDNRYLQLFKNLLKLEELDISKNSLS 659
Query 245 LANTSI--------RNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW 296
+ + +NLSL+ + L + LK NL LDLS+N L V
Sbjct 660 FLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLK--NLETLDLSHNQLTTVPERLSNC 717
Query 297 LPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L+ L+ N I+ L + L F +RYL+L S Q I S P+
Sbjct 718 SRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLS-SNKIQMIQKTSFPE 765
Score = 39.7 bits (91), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 105/451 (23%), Positives = 173/451 (38%), Gaps = 86/451 (19%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 35 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 94
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N +++P L LK L L N+L ++ +L L L
Sbjct 95 NCXXXXXXXXXXXXPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 151
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 152 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 211
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 212 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 254
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 255 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 295
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 296 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 355
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 356 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 399
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIG 444
L N I F L+V+DL +N+I
Sbjct 400 LGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 430
Score = 34.3 bits (77), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 34/115 (30%), Positives = 50/115 (43%), Gaps = 2/115 (2%)
Query 45 VPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVL 104
V D +P N+ L+L N L+ L +LD+ N ++ + L LK L
Sbjct 665 VFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNL 724
Query 105 NLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHN 157
L++N++ L+ L L L SN IQ I+ F + NL L L HN
Sbjct 725 ILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHN 779
>7ytp_B B Toll-like receptor 7
Length=975
Score = 85.5 bits (210), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 104/357 (29%), Positives = 154/357 (43%), Gaps = 59/357 (17%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ L++ N I IKS+ F L LK L+LS + S +TL F LA L L+ + N
Sbjct 492 QTLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLIS-QTLNGSEFQPLAE--LRYLDFSNN 548
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + S AF L LEVLD+ N + E I + L++ K L++
Sbjct 549 RLDLLHSTAFEELRKLEVLDISSNS--------HYFQSEGITHM-LNFTKNLKV------ 593
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTI----LDLSNNNIANINDDMLEGLEKLE 533
LQ+LM+ + + S + LR L LD+ + N + + L KLE
Sbjct 594 ----LQKLMMNDNDISSSTSRTMESESLRTLEFRGNHLDVLWRDGDNRYLQLFKNLLKLE 649
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
LD+ N+L+ L G P +L L+L NG E + L L+ +DL
Sbjct 650 ELDISKNSLSFLPSGVFDGMP-------PNLKNLSLAKNGLKSFIWEKLRYLKNLETLDL 702
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR------------------ 635
N L T+P + N SLK+L L+ N I S+ K AF+
Sbjct 703 SHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTS 762
Query 636 -------NLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
NL L + N F CTC+++ WFV W+ T IP L++ C P + G
Sbjct 763 FPENVLNNLKMLLLHHNRFLCTCDAV-WFVWWVQHTEVTIPYLATDVTCVGPGAHKG 818
Score = 57.0 bits (136), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 67/230 (29%), Positives = 102/230 (44%), Gaps = 38/230 (17%)
Query 417 NKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSF 476
N I I + + L ++E+L LG N +R Y+SY+ + +++F
Sbjct 154 NNIFSIRKEQLTELANIEILYLGQNCY--------YRN-----PCYVSYS----IEKDAF 196
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILD 536
+ L+ L L+ NV + P+ LT L L NN IA I +D L +L+ILD
Sbjct 197 LNLTKLKVLSLKD---NNVTTVPTVLP--STLTELYLYNNMIAEIQEDDFNNLNQLQILD 251
Query 537 LQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L N R + P P ++N +IPV F L ELK++ L N
Sbjct 252 LS-GNCPRCYNAPFPCTPC--------------KNNSPLQIPVNAFDALTELKVLRLHSN 296
Query 597 NLNTLPASVFNNQVSLKSLNLQKN-LITSVEKKVFGPAFRNLTELDMRFN 645
+L +P F N +L+ L+L +N L + F NL +LD+ FN
Sbjct 297 SLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFN 346
Score = 53.5 bits (127), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 44/147 (30%), Positives = 76/147 (52%), Gaps = 8/147 (5%)
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW-RGLENIFEIYL 463
A + L +L L N + + F + +L+ LDL N + +E+ ++ L N+ ++ L
Sbjct 284 ALTELKVLRLHSNSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDL 343
Query 464 SYNKYLQLTRNS------FALVPSLQRLMLRRVALKNVDS-SPSPFQPLRNLTILDLSNN 516
S+N LQ+ R S F+ + SL+ L +R K + S SP L+NL +LDL N
Sbjct 344 SFNFELQVYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTN 403
Query 517 NIANINDDMLEGLEKLEILDLQHNNLA 543
I N M + ++L+++DL N ++
Sbjct 404 FIKIANLSMFKQFKRLKVIDLSVNKIS 430
Score = 49.7 bits (117), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 75/260 (29%), Positives = 113/260 (43%), Gaps = 24/260 (9%)
Query 369 GIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I+ + F L LK LSL N+ T++ T+ T L L N I++I+ D F
Sbjct 190 SIEKDAFLNLTKLKVLSLKDNNVTTVPTVLPSTLTELY--------LYNNMIAEIQEDDF 241
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY-LSYNKYLQLTRNSFALVPSLQRLM 486
+ L L++LDL +G R F N LQ+ N+F + L+ L
Sbjct 242 NNLNQLQILDL---------SGNCPRCYNAPFPCTPCKNNSPLQIPVNAFDALTELKVLR 292
Query 487 LRRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN-IND-DMLEGLEKLEILDLQHNNLAR 544
L +L++V P F+ + NL LDLS N +A I D L L L LDL N +
Sbjct 293 LHSNSLQHV--PPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQ 350
Query 545 LWKHA-NPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPA 603
+++ + N LK L L I + +L L+++DLG N +
Sbjct 351 VYRASMNLSQAFSSLKSLKILRIRGYVFKELKSFQLSPLHNLQNLEVLDLGTNFIKIANL 410
Query 604 SVFNNQVSLKSLNLQKNLIT 623
S+F LK ++L N I+
Sbjct 411 SMFKQFKRLKVIDLSVNKIS 430
Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 80/289 (28%), Positives = 125/289 (43%), Gaps = 28/289 (10%)
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLM 131
+Y Q +LD+ N+I ++ Q L LK LNL N +SQ L+ F L L
Sbjct 489 KYGQ--TLDLSKNSIFFIKSSDFQHLSFLKCLNLSGNLISQTLNGSEFQPLAELRYLDFS 546
Query 132 SNSIQKIKNNPFVKQKNLITLDLSHN-------GLSSTKLGTQVQLENLQELLLSNNKIQ 184
+N + + + F + + L LD+S N G++ L L+ LQ+L++++N I
Sbjct 547 NNRLDLLHSTAFEELRKLEVLDISSNSHYFQSEGITHM-LNFTKNLKVLQKLMMNDNDIS 605
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE 244
+ S ++ + SL+ LE N + R LF N ++L K L
Sbjct 606 SSTSRTME---SESLRTLEFRGNHLDVLWRD---GDNRYLQLFKNLLKLEELDISKNSLS 659
Query 245 LANTSI--------RNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW 296
+ + +NLSL+ + L + LK NL LDLS+N L V
Sbjct 660 FLPSGVFDGMPPNLKNLSLAKNGLKSFIWEKLRYLK--NLETLDLSHNQLTTVPERLSNC 717
Query 297 LPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L+ L+ N I+ L + L F +RYL+L S Q I S P+
Sbjct 718 SRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLS-SNKIQMIQKTSFPE 765
Score = 39.7 bits (91), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 105/451 (23%), Positives = 173/451 (38%), Gaps = 86/451 (19%)
Query 25 TTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
T + +H + DC+ LT++P +PTN T L LT N + + A+F R L +D
Sbjct 35 TLDVSKNHVIVDCTDKHLTEIPGGIPTNTTNLTLTINHIPDISPASFHRLVHLVEIDFRC 94
Query 85 NTIS--------------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
N +++P L LK L L N+L ++ +L L L
Sbjct 95 NCXXXXXXXXXXXXPRRLQIKPRSFSGLTYLKSLYLDGNQLLEIPQ---GLPPSLQLLSL 151
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEE 190
+N+I I+ + N+ L L N +E L L+ K+ +LK
Sbjct 152 EANNIFSIRKEQLTELANIEILYLGQNCYYRNPCYVSYSIEKDAFLNLTKLKVLSLKDNN 211
Query 191 LDIFAN---SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+ S+L +L L +N I E F+ LN +Q+ L+L+
Sbjct 212 VTTVPTVLPSTLTELYLYNNMIAEIQEDDFNN--------LNQLQI---------LDLSG 254
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
R N F N + L + N +F L +L+ L
Sbjct 255 NCPR-----------CYNAPFPCTPCKNNSPLQIPVN--------AFDALTELKVLRLHS 295
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS-------LASLPKID-DFSFQWLKCLEH 359
N++QH+ + N++ L+L ++F + I L +L ++D F+F+
Sbjct 296 NSLQHVPPRWFKNINNLQELDLSQNFLAKEIGDAKFLHFLPNLIQLDLSFNFELQVYRAS 355
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH------ILN 413
+N+ S F+ L +LK L +R + S SPLH +L+
Sbjct 356 MNL---------SQAFSSLKSLKIL-------RIRGYVFKELKSFQLSPLHNLQNLEVLD 399
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIG 444
L N I F L+V+DL +N+I
Sbjct 400 LGTNFIKIANLSMFKQFKRLKVIDLSVNKIS 430
Score = 34.3 bits (77), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 34/115 (30%), Positives = 50/115 (43%), Gaps = 2/115 (2%)
Query 45 VPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVL 104
V D +P N+ L+L N L+ L +LD+ N ++ + L LK L
Sbjct 665 VFDGMPPNLKNLSLAKNGLKSFIWEKLRYLKNLETLDLSHNQLTTVPERLSNCSRSLKNL 724
Query 105 NLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHN 157
L++N++ L+ L L L SN IQ I+ F + NL L L HN
Sbjct 725 ILKNNQIRSLTKYFLQDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLKMLLLHHN 779
>7b1c_A C Toll-like receptor
Length=768
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 118/433 (27%), Positives = 184/433 (42%), Gaps = 57/433 (13%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
+NLT L L YN LN + F L LE L YN+I+ L + S +GL ++R LNL+
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLR--- 222
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
+ + D +F LK L L + N + +F+ LK L L+N+ L
Sbjct 223 ------VNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNN-RKL 275
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLG---LNEIGQELTGQ 450
TL E +L L ++NL+ N + + S + L+LG LN + +EL
Sbjct 276 VTLPEELLANLKE--LTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 451 EWRGLENIFEIYLSYNKYLQLTRNSFALVPS--------LQRLMLRRVALKNVDSSPSPF 502
+ + + L L N +P LQ L L L+++ S F
Sbjct 334 QPQL------------QVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSL--SEKAF 379
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA---------RLWKHANPGG 553
L+NL L L NN + I + G KLE + +Q+N LA L N
Sbjct 380 TKLKNLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDNT 439
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L+ L LH+ N N I + + + E++ +DL N L L + Q ++
Sbjct 440 PFQVLQKLRILHLRN---NSISTIFQDWYINNLEMQSLDLSFNKLPGLSYTQLQFQSNI- 495
Query 614 SLNLQKNLITSV---EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPE 670
+LNL N I+ V + P R +D+ NP +C C ++ F+ I + +
Sbjct 496 TLNLSNNEISQVLLIDDLDLQPYQR--INVDLNHNPLNCNCNALK-FIQLIQSKAEHGLQ 552
Query 671 LSSHYL-CNTPPH 682
+ L C+ PP+
Sbjct 553 FNVDQLRCSEPPN 565
Score = 75.9 bits (185), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 106/394 (27%), Positives = 172/394 (44%), Gaps = 53/394 (13%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L + HN+L P F S LT L + +N +++++P L L L+ L+L +N++
Sbjct 144 NLKRLTIEHNKLNLQPGT-FEALSNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDI 202
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
LS +F ++L L+L N I+ N F K L L+++ N S G + +
Sbjct 203 KSLSAGSFNGLSSLRMLNLRVNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENK 262
Query 172 NLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L+ L+L+NN+ EEL AN L + LS N + + L L
Sbjct 263 KLKTLILTNNRKLVTLPEEL--LANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGY 320
Query 231 VQLGPSLTEKLCLELA----------------------NTSIRNLSLSNSQLSTTSNTTF 268
+L SL E+L + N ++ L LS+++L + S F
Sbjct 321 NRLN-SLPEELLSDQPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAF 379
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LK NL L L N L + F+ P+LE +++ N + +LH
Sbjct 380 TKLK--NLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQL------ALHA-------- 423
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
SF + +S+A D+ FQ L+ L L++ +N I I + + NL+ SL
Sbjct 424 --NSFINEELSIAD---NDNTPFQVLQKLRILHLRNNSISTIFQDWYIN--NLEMQSLDL 476
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SF L L ++ L LNL+ N+IS++
Sbjct 477 SFNKLPGL---SYTQLQFQSNITLNLSNNEISQV 507
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 78/299 (26%), Positives = 138/299 (46%), Gaps = 28/299 (9%)
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
F+ ++ LE+L + + I + F+G +NLK L++ ++ +L+ T E +L +
Sbjct 116 FEGMEQLENLTLA-RGVVSIDRDTFSGFLNLKRLTIEHNKLNLQPGTFEALSNLTY---- 170
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
L L N +++I+ F L LE L L N+I + L+ + GL ++ + L NK
Sbjct 171 -LGLVYNGLNEIQPGLFDGLESLEALSLSYNDI-KSLSAGSFNGLSSLRMLNLRVNKIES 228
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSP-FQPLRNLTILDLSNN-NIANINDDMLEG 528
N+FA + L RL + L S P F + L L L+NN + + +++L
Sbjct 229 FDANTFASLKELSRL---EITLNPFVSLPRGLFSENKKLKTLILTNNRKLVTLPEELLAN 285
Query 529 LEKLEILDLQHNNLARLWKHANPGG----------------PIYFLKGLSHLHILNLESN 572
L++L +++L HN + L + G P L L +LNL+ N
Sbjct 286 LKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSDQPQLQVLNLDHN 345
Query 573 GFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
+ IP + EL+ + L N L +L F +LK L+L+ N + ++ + +F
Sbjct 346 QLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENNQLQTIPQFLFS 404
Score = 69.7 bits (169), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 52/165 (32%), Positives = 84/165 (51%), Gaps = 7/165 (4%)
Query 41 KLTQVPDDLPTNI---TVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
KL +P++L N+ TV+NL+HN + LP + + S + L++G+N ++ L EL
Sbjct 274 KLVTLPEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
P L+VLNL HN+L + D L L+L N ++ + F K KNL L L +N
Sbjct 334 QPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENN 393
Query 158 GLSSTKLGTQVQLENLQELLLSNNKI----QALKSEELDIFANSS 198
L + L+E+ + NN++ + +EEL I N +
Sbjct 394 QLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDN 438
Score = 69.7 bits (169), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 77/263 (29%), Positives = 128/263 (49%), Gaps = 26/263 (10%)
Query 369 GIKSNM--FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDA 426
GI+ N F G+ L+ L+L+ S+ T F++L L + NK++ ++
Sbjct 108 GIRYNAKYFEGMEQLENLTLARGVVSIDRDTFSGFLNLKR-----LTIEHNKLN-LQPGT 161
Query 427 FSWLGHLEVLDL---GLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
F L +L L L GLNEI L + GLE++ + LSYN L+ SF + SL+
Sbjct 162 FEALSNLTYLGLVYNGLNEIQPGL----FDGLESLEALSLSYNDIKSLSAGSFNGLSSLR 217
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN-NL 542
L LR +++ D++ F L+ L+ L+++ N ++ + +KL+ L L +N L
Sbjct 218 MLNLRVNKIESFDANT--FASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNNRKL 275
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLP 602
L P L L L ++NL NG +P + + ++LG N LN+LP
Sbjct 276 VTL--------PEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLP 327
Query 603 ASVFNNQVSLKSLNLQKNLITSV 625
+ ++Q L+ LNL N + S+
Sbjct 328 EELLSDQPQLQVLNLDHNQLESI 350
Score = 57.4 bits (137), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 46/146 (32%), Positives = 72/146 (49%), Gaps = 14/146 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
+ L NLT+ + +I+ D G L+ L ++HN L + PG + L
Sbjct 119 MEQLENLTLA----RGVVSIDRDTFSGFLNLKRLTIEHNKL-----NLQPGT----FEAL 165
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
S+L L L NG +EI +F L L+ + L N++ +L A FN SL+ LNL+ N
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLRVNK 225
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPF 647
I S + F + + L+ L++ NPF
Sbjct 226 IESFDANTFA-SLKELSRLEITLNPF 250
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 35/126 (28%), Positives = 60/126 (48%), Gaps = 16/126 (13%)
Query 3 QTLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPD-DLPT------NITV 55
+ L C + P CA TV + +CS LT+ PD +P+ N
Sbjct 577 KDLLCDFESADDCPKDCQCAMRLLDHTV---IVNCSGRGLTEFPDLPIPSQLHEDFNALE 633
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP-MLKVLNLQHNELSQL 114
+++ +N+L +LP N T+++++T L N+I L P +P L++++L N L +
Sbjct 634 VHVENNRLTKLP--NLTKHNEITQLYARNNSIQNLLP---HNIPSKLRIIDLSQNLLKMI 688
Query 115 SDKTFA 120
D T A
Sbjct 689 DDSTLA 694
>5ijc_A A Toll-like receptor 4,Variable lymphocyte receptor B
Length=635
Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 151/638 (24%), Positives = 263/638 (41%), Gaps = 93/638 (15%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL++V DD+P++ ++L+ N L+ L + +F+ +S+L LD+ I +E +
Sbjct 55 CMDQKLSKVXDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH 114
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + S +F+ T+L L + + +++ P + L L+++H
Sbjct 115 GLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAH 174
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLK--KLELSSNQIKEFS 213
N + S KL L NL + LS N IQ + +L + L++S N I
Sbjct 175 NFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQ 234
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
F I +L L L S K CL+ LA + L L L +
Sbjct 235 DQAFQGI-KLHELTLRG-NFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIM 292
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL- 327
GL + L+Y N ++++ + ++ + SL G+ +++YL
Sbjct 293 EGLCDVTIDEFRLTYTN-------------DFSDDIVKFHCLANVSAMSLAGV-SIKYLE 338
Query 328 NLKRSFTKQSISL--ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
++ + F QS+S+ L + +LK L L M I K L +L YL
Sbjct 339 DVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLT-LTMNKGSISFKK----VALPSLSYLD 393
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS + S ++ L + L L+L+ N + I S F L L+ LD + + +
Sbjct 394 LSRNALSFSGCC--SYSDLGTNSLRHLDLSFNG-AIIMSANFMGLEELQHLDFQHSTLKR 450
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+ LE + + +SY F + SL L + + K+ ++ + F
Sbjct 451 VTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKD-NTLSNVFANT 509
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT LDLS + I+ + + L +L++L++ HNNL
Sbjct 510 TNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNL----------------------- 546
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L L+S+ +++ L+ LK + L N L ++P +F+ SL+ + L
Sbjct 547 -LFLDSSHYNQ--------LYSLKELALDTNQLKSVPDGIFDRLTSLQKIWLHT------ 591
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
NP+DC+C I + W+N+
Sbjct 592 -------------------NPWDCSCPRIDYLSRWLNK 610
>7b1c_B A Toll-like receptor
Length=768
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 118/433 (27%), Positives = 184/433 (42%), Gaps = 57/433 (13%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
+NLT L L YN LN + F L LE L YN+I+ L + S +GL ++R LNL+
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLR--- 222
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
+ + D +F LK L L + N + +F+ LK L L+N+ L
Sbjct 223 ------VNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNN-RKL 275
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLG---LNEIGQELTGQ 450
TL E +L L ++NL+ N + + S + L+LG LN + +EL
Sbjct 276 VTLPEELLANLKE--LTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 451 EWRGLENIFEIYLSYNKYLQLTRNSFALVPS--------LQRLMLRRVALKNVDSSPSPF 502
+ + + L L N +P LQ L L L+++ S F
Sbjct 334 QPQL------------QVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSL--SEKAF 379
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA---------RLWKHANPGG 553
L+NL L L NN + I + G KLE + +Q+N LA L N
Sbjct 380 TKLKNLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDNT 439
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L+ L LH+ N N I + + + E++ +DL N L L + Q ++
Sbjct 440 PFQVLQKLRILHLRN---NSISTIFQDWYINNLEMQSLDLSFNKLPGLSYTQLQFQSNI- 495
Query 614 SLNLQKNLITSV---EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPE 670
+LNL N I+ V + P R +D+ NP +C C ++ F+ I + +
Sbjct 496 TLNLSNNEISQVLLIDDLDLQPYQR--INVDLNHNPLNCNCNALK-FIQLIQSKAEHGLQ 552
Query 671 LSSHYL-CNTPPH 682
+ L C+ PP+
Sbjct 553 FNVDQLRCSEPPN 565
Score = 75.9 bits (185), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 106/394 (27%), Positives = 172/394 (44%), Gaps = 53/394 (13%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L + HN+L P F S LT L + +N +++++P L L L+ L+L +N++
Sbjct 144 NLKRLTIEHNKLNLQPGT-FEALSNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDI 202
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
LS +F ++L L+L N I+ N F K L L+++ N S G + +
Sbjct 203 KSLSAGSFNGLSSLRMLNLRVNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENK 262
Query 172 NLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L+ L+L+NN+ EEL AN L + LS N + + L L
Sbjct 263 KLKTLILTNNRKLVTLPEEL--LANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGY 320
Query 231 VQLGPSLTEKLCLELA----------------------NTSIRNLSLSNSQLSTTSNTTF 268
+L SL E+L + N ++ L LS+++L + S F
Sbjct 321 NRLN-SLPEELLSDQPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAF 379
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LK NL L L N L + F+ P+LE +++ N + +LH
Sbjct 380 TKLK--NLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQL------ALHA-------- 423
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
SF + +S+A D+ FQ L+ L L++ +N I I + + NL+ SL
Sbjct 424 --NSFINEELSIAD---NDNTPFQVLQKLRILHLRNNSISTIFQDWYIN--NLEMQSLDL 476
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SF L L ++ L LNL+ N+IS++
Sbjct 477 SFNKLPGL---SYTQLQFQSNITLNLSNNEISQV 507
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 78/299 (26%), Positives = 138/299 (46%), Gaps = 28/299 (9%)
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
F+ ++ LE+L + + I + F+G +NLK L++ ++ +L+ T E +L +
Sbjct 116 FEGMEQLENLTLA-RGVVSIDRDTFSGFLNLKRLTIEHNKLNLQPGTFEALSNLTY---- 170
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
L L N +++I+ F L LE L L N+I + L+ + GL ++ + L NK
Sbjct 171 -LGLVYNGLNEIQPGLFDGLESLEALSLSYNDI-KSLSAGSFNGLSSLRMLNLRVNKIES 228
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSP-FQPLRNLTILDLSNN-NIANINDDMLEG 528
N+FA + L RL + L S P F + L L L+NN + + +++L
Sbjct 229 FDANTFASLKELSRL---EITLNPFVSLPRGLFSENKKLKTLILTNNRKLVTLPEELLAN 285
Query 529 LEKLEILDLQHNNLARLWKHANPGG----------------PIYFLKGLSHLHILNLESN 572
L++L +++L HN + L + G P L L +LNL+ N
Sbjct 286 LKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSDQPQLQVLNLDHN 345
Query 573 GFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
+ IP + EL+ + L N L +L F +LK L+L+ N + ++ + +F
Sbjct 346 QLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENNQLQTIPQFLFS 404
Score = 69.7 bits (169), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 52/165 (32%), Positives = 84/165 (51%), Gaps = 7/165 (4%)
Query 41 KLTQVPDDLPTNI---TVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
KL +P++L N+ TV+NL+HN + LP + + S + L++G+N ++ L EL
Sbjct 274 KLVTLPEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
P L+VLNL HN+L + D L L+L N ++ + F K KNL L L +N
Sbjct 334 QPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENN 393
Query 158 GLSSTKLGTQVQLENLQELLLSNNKI----QALKSEELDIFANSS 198
L + L+E+ + NN++ + +EEL I N +
Sbjct 394 QLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDN 438
Score = 69.7 bits (169), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 77/263 (29%), Positives = 128/263 (49%), Gaps = 26/263 (10%)
Query 369 GIKSNM--FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDA 426
GI+ N F G+ L+ L+L+ S+ T F++L L + NK++ ++
Sbjct 108 GIRYNAKYFEGMEQLENLTLARGVVSIDRDTFSGFLNLKR-----LTIEHNKLN-LQPGT 161
Query 427 FSWLGHLEVLDL---GLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
F L +L L L GLNEI L + GLE++ + LSYN L+ SF + SL+
Sbjct 162 FEALSNLTYLGLVYNGLNEIQPGL----FDGLESLEALSLSYNDIKSLSAGSFNGLSSLR 217
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN-NL 542
L LR +++ D++ F L+ L+ L+++ N ++ + +KL+ L L +N L
Sbjct 218 MLNLRVNKIESFDANT--FASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNNRKL 275
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLP 602
L P L L L ++NL NG +P + + ++LG N LN+LP
Sbjct 276 VTL--------PEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLP 327
Query 603 ASVFNNQVSLKSLNLQKNLITSV 625
+ ++Q L+ LNL N + S+
Sbjct 328 EELLSDQPQLQVLNLDHNQLESI 350
Score = 57.8 bits (138), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 46/146 (32%), Positives = 72/146 (49%), Gaps = 14/146 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
+ L NLT+ + +I+ D G L+ L ++HN L + PG + L
Sbjct 119 MEQLENLTLA----RGVVSIDRDTFSGFLNLKRLTIEHNKL-----NLQPGT----FEAL 165
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
S+L L L NG +EI +F L L+ + L N++ +L A FN SL+ LNL+ N
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLRVNK 225
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPF 647
I S + F + + L+ L++ NPF
Sbjct 226 IESFDANTFA-SLKELSRLEITLNPF 250
Score = 37.0 bits (84), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 35/126 (28%), Positives = 60/126 (48%), Gaps = 16/126 (13%)
Query 3 QTLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPD-DLPT------NITV 55
+ L C + P CA TV + +CS LT+ PD +P+ N
Sbjct 577 KDLLCDFESADDCPKDCQCAMRLLDHTV---IVNCSGRGLTEFPDLPIPSQLHEDFNALE 633
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP-MLKVLNLQHNELSQL 114
+++ +N+L +LP N T+++++T L N+I L P +P L++++L N L +
Sbjct 634 VHVENNRLTKLP--NLTKHNEITQLYARNNSIQNLLP---HNIPSKLRIIDLSQNLLKMI 688
Query 115 SDKTFA 120
D T A
Sbjct 689 DDSTLA 694
>7b1b_D B Toll-like receptor
Length=768
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 118/433 (27%), Positives = 184/433 (42%), Gaps = 57/433 (13%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
+NLT L L YN LN + F L LE L YN+I+ L + S +GL ++R LNL+
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLR--- 222
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
+ + D +F LK L L + N + +F+ LK L L+N+ L
Sbjct 223 ------VNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNN-RKL 275
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLG---LNEIGQELTGQ 450
TL E +L L ++NL+ N + + S + L+LG LN + +EL
Sbjct 276 VTLPEELLANLKE--LTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 451 EWRGLENIFEIYLSYNKYLQLTRNSFALVPS--------LQRLMLRRVALKNVDSSPSPF 502
+ + + L L N +P LQ L L L+++ S F
Sbjct 334 QPQL------------QVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSL--SEKAF 379
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA---------RLWKHANPGG 553
L+NL L L NN + I + G KLE + +Q+N LA L N
Sbjct 380 TKLKNLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDNT 439
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L+ L LH+ N N I + + + E++ +DL N L L + Q ++
Sbjct 440 PFQVLQKLRILHLRN---NSISTIFQDWYINNLEMQSLDLSFNKLPGLSYTQLQFQSNI- 495
Query 614 SLNLQKNLITSV---EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPE 670
+LNL N I+ V + P R +D+ NP +C C ++ F+ I + +
Sbjct 496 TLNLSNNEISQVLLIDDLDLQPYQR--INVDLNHNPLNCNCNALK-FIQLIQSKAEHGLQ 552
Query 671 LSSHYL-CNTPPH 682
+ L C+ PP+
Sbjct 553 FNVDQLRCSEPPN 565
Score = 75.9 bits (185), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 106/394 (27%), Positives = 172/394 (44%), Gaps = 53/394 (13%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L + HN+L P F S LT L + +N +++++P L L L+ L+L +N++
Sbjct 144 NLKRLTIEHNKLNLQPGT-FEALSNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDI 202
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
LS +F ++L L+L N I+ N F K L L+++ N S G + +
Sbjct 203 KSLSAGSFNGLSSLRMLNLRVNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENK 262
Query 172 NLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L+ L+L+NN+ EEL AN L + LS N + + L L
Sbjct 263 KLKTLILTNNRKLVTLPEEL--LANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGY 320
Query 231 VQLGPSLTEKLCLELA----------------------NTSIRNLSLSNSQLSTTSNTTF 268
+L SL E+L + N ++ L LS+++L + S F
Sbjct 321 NRLN-SLPEELLSDQPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAF 379
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LK NL L L N L + F+ P+LE +++ N + +LH
Sbjct 380 TKLK--NLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQL------ALHA-------- 423
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
SF + +S+A D+ FQ L+ L L++ +N I I + + NL+ SL
Sbjct 424 --NSFINEELSIAD---NDNTPFQVLQKLRILHLRNNSISTIFQDWYIN--NLEMQSLDL 476
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SF L L ++ L LNL+ N+IS++
Sbjct 477 SFNKLPGL---SYTQLQFQSNITLNLSNNEISQV 507
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 78/299 (26%), Positives = 138/299 (46%), Gaps = 28/299 (9%)
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
F+ ++ LE+L + + I + F+G +NLK L++ ++ +L+ T E +L +
Sbjct 116 FEGMEQLENLTLA-RGVVSIDRDTFSGFLNLKRLTIEHNKLNLQPGTFEALSNLTY---- 170
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
L L N +++I+ F L LE L L N+I + L+ + GL ++ + L NK
Sbjct 171 -LGLVYNGLNEIQPGLFDGLESLEALSLSYNDI-KSLSAGSFNGLSSLRMLNLRVNKIES 228
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSP-FQPLRNLTILDLSNN-NIANINDDMLEG 528
N+FA + L RL + L S P F + L L L+NN + + +++L
Sbjct 229 FDANTFASLKELSRL---EITLNPFVSLPRGLFSENKKLKTLILTNNRKLVTLPEELLAN 285
Query 529 LEKLEILDLQHNNLARLWKHANPGG----------------PIYFLKGLSHLHILNLESN 572
L++L +++L HN + L + G P L L +LNL+ N
Sbjct 286 LKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSDQPQLQVLNLDHN 345
Query 573 GFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
+ IP + EL+ + L N L +L F +LK L+L+ N + ++ + +F
Sbjct 346 QLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENNQLQTIPQFLFS 404
Score = 69.7 bits (169), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 52/165 (32%), Positives = 84/165 (51%), Gaps = 7/165 (4%)
Query 41 KLTQVPDDLPTNI---TVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
KL +P++L N+ TV+NL+HN + LP + + S + L++G+N ++ L EL
Sbjct 274 KLVTLPEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
P L+VLNL HN+L + D L L+L N ++ + F K KNL L L +N
Sbjct 334 QPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENN 393
Query 158 GLSSTKLGTQVQLENLQELLLSNNKI----QALKSEELDIFANSS 198
L + L+E+ + NN++ + +EEL I N +
Sbjct 394 QLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDN 438
Score = 69.7 bits (169), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 77/263 (29%), Positives = 128/263 (49%), Gaps = 26/263 (10%)
Query 369 GIKSNM--FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDA 426
GI+ N F G+ L+ L+L+ S+ T F++L L + NK++ ++
Sbjct 108 GIRYNAKYFEGMEQLENLTLARGVVSIDRDTFSGFLNLKR-----LTIEHNKLN-LQPGT 161
Query 427 FSWLGHLEVLDL---GLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
F L +L L L GLNEI L + GLE++ + LSYN L+ SF + SL+
Sbjct 162 FEALSNLTYLGLVYNGLNEIQPGL----FDGLESLEALSLSYNDIKSLSAGSFNGLSSLR 217
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN-NL 542
L LR +++ D++ F L+ L+ L+++ N ++ + +KL+ L L +N L
Sbjct 218 MLNLRVNKIESFDANT--FASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNNRKL 275
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLP 602
L P L L L ++NL NG +P + + ++LG N LN+LP
Sbjct 276 VTL--------PEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLP 327
Query 603 ASVFNNQVSLKSLNLQKNLITSV 625
+ ++Q L+ LNL N + S+
Sbjct 328 EELLSDQPQLQVLNLDHNQLESI 350
Score = 57.8 bits (138), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 46/146 (32%), Positives = 72/146 (49%), Gaps = 14/146 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
+ L NLT+ + +I+ D G L+ L ++HN L + PG + L
Sbjct 119 MEQLENLTLA----RGVVSIDRDTFSGFLNLKRLTIEHNKL-----NLQPGT----FEAL 165
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
S+L L L NG +EI +F L L+ + L N++ +L A FN SL+ LNL+ N
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLRVNK 225
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPF 647
I S + F + + L+ L++ NPF
Sbjct 226 IESFDANTFA-SLKELSRLEITLNPF 250
Score = 37.0 bits (84), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 35/126 (28%), Positives = 60/126 (48%), Gaps = 16/126 (13%)
Query 3 QTLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPD-DLPT------NITV 55
+ L C + P CA TV + +CS LT+ PD +P+ N
Sbjct 577 KDLLCDFESADDCPKDCQCAMRLLDHTV---IVNCSGRGLTEFPDLPIPSQLHEDFNALE 633
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP-MLKVLNLQHNELSQL 114
+++ +N+L +LP N T+++++T L N+I L P +P L++++L N L +
Sbjct 634 VHVENNRLTKLP--NLTKHNEITQLYARNNSIQNLLP---HNIPSKLRIIDLSQNLLKMI 688
Query 115 SDKTFA 120
D T A
Sbjct 689 DDSTLA 694
>7b1c_E B Toll-like receptor
Length=768
Score = 85.1 bits (209), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 118/433 (27%), Positives = 184/433 (42%), Gaps = 57/433 (13%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
+NLT L L YN LN + F L LE L YN+I+ L + S +GL ++R LNL+
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLR--- 222
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
+ + D +F LK L L + N + +F+ LK L L+N+ L
Sbjct 223 ------VNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNN-RKL 275
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLG---LNEIGQELTGQ 450
TL E +L L ++NL+ N + + S + L+LG LN + +EL
Sbjct 276 VTLPEELLANLKE--LTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 451 EWRGLENIFEIYLSYNKYLQLTRNSFALVPS--------LQRLMLRRVALKNVDSSPSPF 502
+ + + L L N +P LQ L L L+++ S F
Sbjct 334 QPQL------------QVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSL--SEKAF 379
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA---------RLWKHANPGG 553
L+NL L L NN + I + G KLE + +Q+N LA L N
Sbjct 380 TKLKNLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDNT 439
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L+ L LH+ N N I + + + E++ +DL N L L + Q ++
Sbjct 440 PFQVLQKLRILHLRN---NSISTIFQDWYINNLEMQSLDLSFNKLPGLSYTQLQFQSNI- 495
Query 614 SLNLQKNLITSV---EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPE 670
+LNL N I+ V + P R +D+ NP +C C ++ F+ I + +
Sbjct 496 TLNLSNNEISQVLLIDDLDLQPYQR--INVDLNHNPLNCNCNALK-FIQLIQSKAEHGLQ 552
Query 671 LSSHYL-CNTPPH 682
+ L C+ PP+
Sbjct 553 FNVDQLRCSEPPN 565
Score = 75.9 bits (185), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 106/394 (27%), Positives = 172/394 (44%), Gaps = 53/394 (13%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L + HN+L P F S LT L + +N +++++P L L L+ L+L +N++
Sbjct 144 NLKRLTIEHNKLNLQPGT-FEALSNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDI 202
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
LS +F ++L L+L N I+ N F K L L+++ N S G + +
Sbjct 203 KSLSAGSFNGLSSLRMLNLRVNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENK 262
Query 172 NLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L+ L+L+NN+ EEL AN L + LS N + + L L
Sbjct 263 KLKTLILTNNRKLVTLPEEL--LANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGY 320
Query 231 VQLGPSLTEKLCLELA----------------------NTSIRNLSLSNSQLSTTSNTTF 268
+L SL E+L + N ++ L LS+++L + S F
Sbjct 321 NRLN-SLPEELLSDQPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAF 379
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LK NL L L N L + F+ P+LE +++ N + +LH
Sbjct 380 TKLK--NLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQL------ALHA-------- 423
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
SF + +S+A D+ FQ L+ L L++ +N I I + + NL+ SL
Sbjct 424 --NSFINEELSIAD---NDNTPFQVLQKLRILHLRNNSISTIFQDWYIN--NLEMQSLDL 476
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SF L L ++ L LNL+ N+IS++
Sbjct 477 SFNKLPGL---SYTQLQFQSNITLNLSNNEISQV 507
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 78/299 (26%), Positives = 138/299 (46%), Gaps = 28/299 (9%)
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
F+ ++ LE+L + + I + F+G +NLK L++ ++ +L+ T E +L +
Sbjct 116 FEGMEQLENLTLA-RGVVSIDRDTFSGFLNLKRLTIEHNKLNLQPGTFEALSNLTY---- 170
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
L L N +++I+ F L LE L L N+I + L+ + GL ++ + L NK
Sbjct 171 -LGLVYNGLNEIQPGLFDGLESLEALSLSYNDI-KSLSAGSFNGLSSLRMLNLRVNKIES 228
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSP-FQPLRNLTILDLSNN-NIANINDDMLEG 528
N+FA + L RL + L S P F + L L L+NN + + +++L
Sbjct 229 FDANTFASLKELSRL---EITLNPFVSLPRGLFSENKKLKTLILTNNRKLVTLPEELLAN 285
Query 529 LEKLEILDLQHNNLARLWKHANPGG----------------PIYFLKGLSHLHILNLESN 572
L++L +++L HN + L + G P L L +LNL+ N
Sbjct 286 LKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSDQPQLQVLNLDHN 345
Query 573 GFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
+ IP + EL+ + L N L +L F +LK L+L+ N + ++ + +F
Sbjct 346 QLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENNQLQTIPQFLFS 404
Score = 69.7 bits (169), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 52/165 (32%), Positives = 84/165 (51%), Gaps = 7/165 (4%)
Query 41 KLTQVPDDLPTNI---TVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
KL +P++L N+ TV+NL+HN + LP + + S + L++G+N ++ L EL
Sbjct 274 KLVTLPEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
P L+VLNL HN+L + D L L+L N ++ + F K KNL L L +N
Sbjct 334 QPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENN 393
Query 158 GLSSTKLGTQVQLENLQELLLSNNKI----QALKSEELDIFANSS 198
L + L+E+ + NN++ + +EEL I N +
Sbjct 394 QLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDN 438
Score = 69.7 bits (169), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 77/263 (29%), Positives = 128/263 (49%), Gaps = 26/263 (10%)
Query 369 GIKSNM--FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDA 426
GI+ N F G+ L+ L+L+ S+ T F++L L + NK++ ++
Sbjct 108 GIRYNAKYFEGMEQLENLTLARGVVSIDRDTFSGFLNLKR-----LTIEHNKLN-LQPGT 161
Query 427 FSWLGHLEVLDL---GLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
F L +L L L GLNEI L + GLE++ + LSYN L+ SF + SL+
Sbjct 162 FEALSNLTYLGLVYNGLNEIQPGL----FDGLESLEALSLSYNDIKSLSAGSFNGLSSLR 217
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN-NL 542
L LR +++ D++ F L+ L+ L+++ N ++ + +KL+ L L +N L
Sbjct 218 MLNLRVNKIESFDANT--FASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNNRKL 275
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLP 602
L P L L L ++NL NG +P + + ++LG N LN+LP
Sbjct 276 VTL--------PEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLP 327
Query 603 ASVFNNQVSLKSLNLQKNLITSV 625
+ ++Q L+ LNL N + S+
Sbjct 328 EELLSDQPQLQVLNLDHNQLESI 350
Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 46/146 (32%), Positives = 72/146 (49%), Gaps = 14/146 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
+ L NLT+ + +I+ D G L+ L ++HN L + PG + L
Sbjct 119 MEQLENLTLA----RGVVSIDRDTFSGFLNLKRLTIEHNKL-----NLQPGT----FEAL 165
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
S+L L L NG +EI +F L L+ + L N++ +L A FN SL+ LNL+ N
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLRVNK 225
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPF 647
I S + F + + L+ L++ NPF
Sbjct 226 IESFDANTFA-SLKELSRLEITLNPF 250
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 35/126 (28%), Positives = 60/126 (48%), Gaps = 16/126 (13%)
Query 3 QTLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPD-DLPT------NITV 55
+ L C + P CA TV + +CS LT+ PD +P+ N
Sbjct 577 KDLLCDFESADDCPKDCQCAMRLLDHTV---IVNCSGRGLTEFPDLPIPSQLHEDFNALE 633
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP-MLKVLNLQHNELSQL 114
+++ +N+L +LP N T+++++T L N+I L P +P L++++L N L +
Sbjct 634 VHVENNRLTKLP--NLTKHNEITQLYARNNSIQNLLP---HNIPSKLRIIDLSQNLLKMI 688
Query 115 SDKTFA 120
D T A
Sbjct 689 DDSTLA 694
>7b1d_B C Toll-like receptor
Length=768
Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 118/433 (27%), Positives = 184/433 (42%), Gaps = 57/433 (13%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
+NLT L L YN LN + F L LE L YN+I+ L + S +GL ++R LNL+
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLR--- 222
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
+ + D +F LK L L + N + +F+ LK L L+N+ L
Sbjct 223 ------VNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNN-RKL 275
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLG---LNEIGQELTGQ 450
TL E +L L ++NL+ N + + S + L+LG LN + +EL
Sbjct 276 VTLPEELLANLKE--LTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 451 EWRGLENIFEIYLSYNKYLQLTRNSFALVPS--------LQRLMLRRVALKNVDSSPSPF 502
+ + + L L N +P LQ L L L+++ S F
Sbjct 334 QPQL------------QVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSL--SEKAF 379
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA---------RLWKHANPGG 553
L+NL L L NN + I + G KLE + +Q+N LA L N
Sbjct 380 TKLKNLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDNT 439
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L+ L LH+ N N I + + + E++ +DL N L L + Q ++
Sbjct 440 PFQVLQKLRILHLRN---NSISTIFQDWYINNLEMQSLDLSFNKLPGLSYTQLQFQSNI- 495
Query 614 SLNLQKNLITSV---EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPE 670
+LNL N I+ V + P R +D+ NP +C C ++ F+ I + +
Sbjct 496 TLNLSNNEISQVLLIDDLDLQPYQR--INVDLNHNPLNCNCNALK-FIQLIQSKAEHGLQ 552
Query 671 LSSHYL-CNTPPH 682
+ L C+ PP+
Sbjct 553 FNVDQLRCSEPPN 565
Score = 75.9 bits (185), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 106/394 (27%), Positives = 172/394 (44%), Gaps = 53/394 (13%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L + HN+L P F S LT L + +N +++++P L L L+ L+L +N++
Sbjct 144 NLKRLTIEHNKLNLQPGT-FEALSNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDI 202
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
LS +F ++L L+L N I+ N F K L L+++ N S G + +
Sbjct 203 KSLSAGSFNGLSSLRMLNLRVNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENK 262
Query 172 NLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L+ L+L+NN+ EEL AN L + LS N + + L L
Sbjct 263 KLKTLILTNNRKLVTLPEEL--LANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGY 320
Query 231 VQLGPSLTEKLCLELA----------------------NTSIRNLSLSNSQLSTTSNTTF 268
+L SL E+L + N ++ L LS+++L + S F
Sbjct 321 NRLN-SLPEELLSDQPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAF 379
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LK NL L L N L + F+ P+LE +++ N + +LH
Sbjct 380 TKLK--NLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQL------ALHA-------- 423
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
SF + +S+A D+ FQ L+ L L++ +N I I + + NL+ SL
Sbjct 424 --NSFINEELSIAD---NDNTPFQVLQKLRILHLRNNSISTIFQDWYIN--NLEMQSLDL 476
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SF L L ++ L LNL+ N+IS++
Sbjct 477 SFNKLPGL---SYTQLQFQSNITLNLSNNEISQV 507
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 78/299 (26%), Positives = 138/299 (46%), Gaps = 28/299 (9%)
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
F+ ++ LE+L + + I + F+G +NLK L++ ++ +L+ T E +L +
Sbjct 116 FEGMEQLENLTLA-RGVVSIDRDTFSGFLNLKRLTIEHNKLNLQPGTFEALSNLTY---- 170
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
L L N +++I+ F L LE L L N+I + L+ + GL ++ + L NK
Sbjct 171 -LGLVYNGLNEIQPGLFDGLESLEALSLSYNDI-KSLSAGSFNGLSSLRMLNLRVNKIES 228
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSP-FQPLRNLTILDLSNN-NIANINDDMLEG 528
N+FA + L RL + L S P F + L L L+NN + + +++L
Sbjct 229 FDANTFASLKELSRL---EITLNPFVSLPRGLFSENKKLKTLILTNNRKLVTLPEELLAN 285
Query 529 LEKLEILDLQHNNLARLWKHANPGG----------------PIYFLKGLSHLHILNLESN 572
L++L +++L HN + L + G P L L +LNL+ N
Sbjct 286 LKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSDQPQLQVLNLDHN 345
Query 573 GFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
+ IP + EL+ + L N L +L F +LK L+L+ N + ++ + +F
Sbjct 346 QLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENNQLQTIPQFLFS 404
Score = 70.1 bits (170), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 52/165 (32%), Positives = 84/165 (51%), Gaps = 7/165 (4%)
Query 41 KLTQVPDDLPTNI---TVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
KL +P++L N+ TV+NL+HN + LP + + S + L++G+N ++ L EL
Sbjct 274 KLVTLPEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
P L+VLNL HN+L + D L L+L N ++ + F K KNL L L +N
Sbjct 334 QPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENN 393
Query 158 GLSSTKLGTQVQLENLQELLLSNNKI----QALKSEELDIFANSS 198
L + L+E+ + NN++ + +EEL I N +
Sbjct 394 QLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDN 438
Score = 69.3 bits (168), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 77/263 (29%), Positives = 128/263 (49%), Gaps = 26/263 (10%)
Query 369 GIKSNM--FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDA 426
GI+ N F G+ L+ L+L+ S+ T F++L L + NK++ ++
Sbjct 108 GIRYNAKYFEGMEQLENLTLARGVVSIDRDTFSGFLNLKR-----LTIEHNKLN-LQPGT 161
Query 427 FSWLGHLEVLDL---GLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
F L +L L L GLNEI L + GLE++ + LSYN L+ SF + SL+
Sbjct 162 FEALSNLTYLGLVYNGLNEIQPGL----FDGLESLEALSLSYNDIKSLSAGSFNGLSSLR 217
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN-NL 542
L LR +++ D++ F L+ L+ L+++ N ++ + +KL+ L L +N L
Sbjct 218 MLNLRVNKIESFDANT--FASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNNRKL 275
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLP 602
L P L L L ++NL NG +P + + ++LG N LN+LP
Sbjct 276 VTL--------PEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLP 327
Query 603 ASVFNNQVSLKSLNLQKNLITSV 625
+ ++Q L+ LNL N + S+
Sbjct 328 EELLSDQPQLQVLNLDHNQLESI 350
Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 46/146 (32%), Positives = 72/146 (49%), Gaps = 14/146 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
+ L NLT+ + +I+ D G L+ L ++HN L + PG + L
Sbjct 119 MEQLENLTLA----RGVVSIDRDTFSGFLNLKRLTIEHNKL-----NLQPGT----FEAL 165
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
S+L L L NG +EI +F L L+ + L N++ +L A FN SL+ LNL+ N
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLRVNK 225
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPF 647
I S + F + + L+ L++ NPF
Sbjct 226 IESFDANTFA-SLKELSRLEITLNPF 250
Score = 37.0 bits (84), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 35/126 (28%), Positives = 60/126 (48%), Gaps = 16/126 (13%)
Query 3 QTLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPD-DLPT------NITV 55
+ L C + P CA TV + +CS LT+ PD +P+ N
Sbjct 577 KDLLCDFESADDCPKDCQCAMRLLDHTV---IVNCSGRGLTEFPDLPIPSQLHEDFNALE 633
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP-MLKVLNLQHNELSQL 114
+++ +N+L +LP N T+++++T L N+I L P +P L++++L N L +
Sbjct 634 VHVENNRLTKLP--NLTKHNEITQLYARNNSIQNLLP---HNIPSKLRIIDLSQNLLKMI 688
Query 115 SDKTFA 120
D T A
Sbjct 689 DDSTLA 694
>7b1b_A A Toll-like receptor
Length=768
Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 118/433 (27%), Positives = 184/433 (42%), Gaps = 57/433 (13%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
+NLT L L YN LN + F L LE L YN+I+ L + S +GL ++R LNL+
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLR--- 222
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
+ + D +F LK L L + N + +F+ LK L L+N+ L
Sbjct 223 ------VNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNN-RKL 275
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLG---LNEIGQELTGQ 450
TL E +L L ++NL+ N + + S + L+LG LN + +EL
Sbjct 276 VTLPEELLANLKE--LTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 451 EWRGLENIFEIYLSYNKYLQLTRNSFALVPS--------LQRLMLRRVALKNVDSSPSPF 502
+ + + L L N +P LQ L L L+++ S F
Sbjct 334 QPQL------------QVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSL--SEKAF 379
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA---------RLWKHANPGG 553
L+NL L L NN + I + G KLE + +Q+N LA L N
Sbjct 380 TKLKNLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDNT 439
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L+ L LH+ N N I + + + E++ +DL N L L + Q ++
Sbjct 440 PFQVLQKLRILHLRN---NSISTIFQDWYINNLEMQSLDLSFNKLPGLSYTQLQFQSNI- 495
Query 614 SLNLQKNLITSV---EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPE 670
+LNL N I+ V + P R +D+ NP +C C ++ F+ I + +
Sbjct 496 TLNLSNNEISQVLLIDDLDLQPYQR--INVDLNHNPLNCNCNALK-FIQLIQSKAEHGLQ 552
Query 671 LSSHYL-CNTPPH 682
+ L C+ PP+
Sbjct 553 FNVDQLRCSEPPN 565
Score = 75.9 bits (185), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 106/394 (27%), Positives = 172/394 (44%), Gaps = 53/394 (13%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L + HN+L P F S LT L + +N +++++P L L L+ L+L +N++
Sbjct 144 NLKRLTIEHNKLNLQPGT-FEALSNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDI 202
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
LS +F ++L L+L N I+ N F K L L+++ N S G + +
Sbjct 203 KSLSAGSFNGLSSLRMLNLRVNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENK 262
Query 172 NLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L+ L+L+NN+ EEL AN L + LS N + + L L
Sbjct 263 KLKTLILTNNRKLVTLPEEL--LANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGY 320
Query 231 VQLGPSLTEKLCLELA----------------------NTSIRNLSLSNSQLSTTSNTTF 268
+L SL E+L + N ++ L LS+++L + S F
Sbjct 321 NRLN-SLPEELLSDQPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAF 379
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LK NL L L N L + F+ P+LE +++ N + +LH
Sbjct 380 TKLK--NLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQL------ALHA-------- 423
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
SF + +S+A D+ FQ L+ L L++ +N I I + + NL+ SL
Sbjct 424 --NSFINEELSIAD---NDNTPFQVLQKLRILHLRNNSISTIFQDWYIN--NLEMQSLDL 476
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SF L L ++ L LNL+ N+IS++
Sbjct 477 SFNKLPGL---SYTQLQFQSNITLNLSNNEISQV 507
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 78/299 (26%), Positives = 138/299 (46%), Gaps = 28/299 (9%)
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
F+ ++ LE+L + + I + F+G +NLK L++ ++ +L+ T E +L +
Sbjct 116 FEGMEQLENLTLA-RGVVSIDRDTFSGFLNLKRLTIEHNKLNLQPGTFEALSNLTY---- 170
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
L L N +++I+ F L LE L L N+I + L+ + GL ++ + L NK
Sbjct 171 -LGLVYNGLNEIQPGLFDGLESLEALSLSYNDI-KSLSAGSFNGLSSLRMLNLRVNKIES 228
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSP-FQPLRNLTILDLSNN-NIANINDDMLEG 528
N+FA + L RL + L S P F + L L L+NN + + +++L
Sbjct 229 FDANTFASLKELSRL---EITLNPFVSLPRGLFSENKKLKTLILTNNRKLVTLPEELLAN 285
Query 529 LEKLEILDLQHNNLARLWKHANPGG----------------PIYFLKGLSHLHILNLESN 572
L++L +++L HN + L + G P L L +LNL+ N
Sbjct 286 LKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSDQPQLQVLNLDHN 345
Query 573 GFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
+ IP + EL+ + L N L +L F +LK L+L+ N + ++ + +F
Sbjct 346 QLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENNQLQTIPQFLFS 404
Score = 69.7 bits (169), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 52/165 (32%), Positives = 84/165 (51%), Gaps = 7/165 (4%)
Query 41 KLTQVPDDLPTNI---TVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
KL +P++L N+ TV+NL+HN + LP + + S + L++G+N ++ L EL
Sbjct 274 KLVTLPEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
P L+VLNL HN+L + D L L+L N ++ + F K KNL L L +N
Sbjct 334 QPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENN 393
Query 158 GLSSTKLGTQVQLENLQELLLSNNKI----QALKSEELDIFANSS 198
L + L+E+ + NN++ + +EEL I N +
Sbjct 394 QLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDN 438
Score = 69.7 bits (169), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 77/263 (29%), Positives = 128/263 (49%), Gaps = 26/263 (10%)
Query 369 GIKSNM--FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDA 426
GI+ N F G+ L+ L+L+ S+ T F++L L + NK++ ++
Sbjct 108 GIRYNAKYFEGMEQLENLTLARGVVSIDRDTFSGFLNLKR-----LTIEHNKLN-LQPGT 161
Query 427 FSWLGHLEVLDL---GLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
F L +L L L GLNEI L + GLE++ + LSYN L+ SF + SL+
Sbjct 162 FEALSNLTYLGLVYNGLNEIQPGL----FDGLESLEALSLSYNDIKSLSAGSFNGLSSLR 217
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN-NL 542
L LR +++ D++ F L+ L+ L+++ N ++ + +KL+ L L +N L
Sbjct 218 MLNLRVNKIESFDANT--FASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNNRKL 275
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLP 602
L P L L L ++NL NG +P + + ++LG N LN+LP
Sbjct 276 VTL--------PEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLP 327
Query 603 ASVFNNQVSLKSLNLQKNLITSV 625
+ ++Q L+ LNL N + S+
Sbjct 328 EELLSDQPQLQVLNLDHNQLESI 350
Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 46/146 (32%), Positives = 72/146 (49%), Gaps = 14/146 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
+ L NLT+ + +I+ D G L+ L ++HN L + PG + L
Sbjct 119 MEQLENLTLA----RGVVSIDRDTFSGFLNLKRLTIEHNKL-----NLQPGT----FEAL 165
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
S+L L L NG +EI +F L L+ + L N++ +L A FN SL+ LNL+ N
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLRVNK 225
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPF 647
I S + F + + L+ L++ NPF
Sbjct 226 IESFDANTFA-SLKELSRLEITLNPF 250
Score = 37.0 bits (84), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 35/126 (28%), Positives = 60/126 (48%), Gaps = 16/126 (13%)
Query 3 QTLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPD-DLPT------NITV 55
+ L C + P CA TV + +CS LT+ PD +P+ N
Sbjct 577 KDLLCDFESADDCPKDCQCAMRLLDHTV---IVNCSGRGLTEFPDLPIPSQLHEDFNALE 633
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP-MLKVLNLQHNELSQL 114
+++ +N+L +LP N T+++++T L N+I L P +P L++++L N L +
Sbjct 634 VHVENNRLTKLP--NLTKHNEITQLYARNNSIQNLLP---HNIPSKLRIIDLSQNLLKMI 688
Query 115 SDKTFA 120
D T A
Sbjct 689 DDSTLA 694
>7b1d_A B Toll-like receptor
Length=768
Score = 84.7 bits (208), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 118/433 (27%), Positives = 184/433 (42%), Gaps = 57/433 (13%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
+NLT L L YN LN + F L LE L YN+I+ L + S +GL ++R LNL+
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLR--- 222
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
+ + D +F LK L L + N + +F+ LK L L+N+ L
Sbjct 223 ------VNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNN-RKL 275
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLG---LNEIGQELTGQ 450
TL E +L L ++NL+ N + + S + L+LG LN + +EL
Sbjct 276 VTLPEELLANLKE--LTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 451 EWRGLENIFEIYLSYNKYLQLTRNSFALVPS--------LQRLMLRRVALKNVDSSPSPF 502
+ + + L L N +P LQ L L L+++ S F
Sbjct 334 QPQL------------QVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSL--SEKAF 379
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA---------RLWKHANPGG 553
L+NL L L NN + I + G KLE + +Q+N LA L N
Sbjct 380 TKLKNLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDNT 439
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L+ L LH+ N N I + + + E++ +DL N L L + Q ++
Sbjct 440 PFQVLQKLRILHLRN---NSISTIFQDWYINNLEMQSLDLSFNKLPGLSYTQLQFQSNI- 495
Query 614 SLNLQKNLITSV---EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPE 670
+LNL N I+ V + P R +D+ NP +C C ++ F+ I + +
Sbjct 496 TLNLSNNEISQVLLIDDLDLQPYQR--INVDLNHNPLNCNCNALK-FIQLIQSKAEHGLQ 552
Query 671 LSSHYL-CNTPPH 682
+ L C+ PP+
Sbjct 553 FNVDQLRCSEPPN 565
Score = 75.9 bits (185), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 106/394 (27%), Positives = 172/394 (44%), Gaps = 53/394 (13%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L + HN+L P F S LT L + +N +++++P L L L+ L+L +N++
Sbjct 144 NLKRLTIEHNKLNLQPGT-FEALSNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDI 202
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
LS +F ++L L+L N I+ N F K L L+++ N S G + +
Sbjct 203 KSLSAGSFNGLSSLRMLNLRVNKIESFDANTFASLKELSRLEITLNPFVSLPRGLFSENK 262
Query 172 NLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L+ L+L+NN+ EEL AN L + LS N + + L L
Sbjct 263 KLKTLILTNNRKLVTLPEEL--LANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGY 320
Query 231 VQLGPSLTEKLCLELA----------------------NTSIRNLSLSNSQLSTTSNTTF 268
+L SL E+L + N ++ L LS+++L + S F
Sbjct 321 NRLN-SLPEELLSDQPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAF 379
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
LK NL L L N L + F+ P+LE +++ N + +LH
Sbjct 380 TKLK--NLKELHLENNQLQTIPQFLFSGTPKLEEIYMQNNQL------ALHA-------- 423
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
SF + +S+A D+ FQ L+ L L++ +N I I + + NL+ SL
Sbjct 424 --NSFINEELSIAD---NDNTPFQVLQKLRILHLRNNSISTIFQDWYIN--NLEMQSLDL 476
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SF L L ++ L LNL+ N+IS++
Sbjct 477 SFNKLPGL---SYTQLQFQSNITLNLSNNEISQV 507
Score = 75.1 bits (183), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 78/299 (26%), Positives = 138/299 (46%), Gaps = 28/299 (9%)
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
F+ ++ LE+L + + I + F+G +NLK L++ ++ +L+ T E +L +
Sbjct 116 FEGMEQLENLTLA-RGVVSIDRDTFSGFLNLKRLTIEHNKLNLQPGTFEALSNLTY---- 170
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
L L N +++I+ F L LE L L N+I + L+ + GL ++ + L NK
Sbjct 171 -LGLVYNGLNEIQPGLFDGLESLEALSLSYNDI-KSLSAGSFNGLSSLRMLNLRVNKIES 228
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSP-FQPLRNLTILDLSNN-NIANINDDMLEG 528
N+FA + L RL + L S P F + L L L+NN + + +++L
Sbjct 229 FDANTFASLKELSRL---EITLNPFVSLPRGLFSENKKLKTLILTNNRKLVTLPEELLAN 285
Query 529 LEKLEILDLQHNNLARLWKHANPGG----------------PIYFLKGLSHLHILNLESN 572
L++L +++L HN + L + G P L L +LNL+ N
Sbjct 286 LKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSDQPQLQVLNLDHN 345
Query 573 GFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
+ IP + EL+ + L N L +L F +LK L+L+ N + ++ + +F
Sbjct 346 QLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENNQLQTIPQFLFS 404
Score = 69.7 bits (169), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 52/165 (32%), Positives = 84/165 (51%), Gaps = 7/165 (4%)
Query 41 KLTQVPDDLPTNI---TVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
KL +P++L N+ TV+NL+HN + LP + + S + L++G+N ++ L EL
Sbjct 274 KLVTLPEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLPEELLSD 333
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
P L+VLNL HN+L + D L L+L N ++ + F K KNL L L +N
Sbjct 334 QPQLQVLNLDHNQLESIPDYFLERNVELQTLYLSHNRLRSLSEKAFTKLKNLKELHLENN 393
Query 158 GLSSTKLGTQVQLENLQELLLSNNKI----QALKSEELDIFANSS 198
L + L+E+ + NN++ + +EEL I N +
Sbjct 394 QLQTIPQFLFSGTPKLEEIYMQNNQLALHANSFINEELSIADNDN 438
Score = 69.3 bits (168), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 77/263 (29%), Positives = 128/263 (49%), Gaps = 26/263 (10%)
Query 369 GIKSNM--FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDA 426
GI+ N F G+ L+ L+L+ S+ T F++L L + NK++ ++
Sbjct 108 GIRYNAKYFEGMEQLENLTLARGVVSIDRDTFSGFLNLKR-----LTIEHNKLN-LQPGT 161
Query 427 FSWLGHLEVLDL---GLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
F L +L L L GLNEI L + GLE++ + LSYN L+ SF + SL+
Sbjct 162 FEALSNLTYLGLVYNGLNEIQPGL----FDGLESLEALSLSYNDIKSLSAGSFNGLSSLR 217
Query 484 RLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN-NL 542
L LR +++ D++ F L+ L+ L+++ N ++ + +KL+ L L +N L
Sbjct 218 MLNLRVNKIESFDANT--FASLKELSRLEITLNPFVSLPRGLFSENKKLKTLILTNNRKL 275
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLP 602
L P L L L ++NL NG +P + + ++LG N LN+LP
Sbjct 276 VTL--------PEELLANLKELTVVNLSHNGVGNLPESLLSGSSGIIELNLGYNRLNSLP 327
Query 603 ASVFNNQVSLKSLNLQKNLITSV 625
+ ++Q L+ LNL N + S+
Sbjct 328 EELLSDQPQLQVLNLDHNQLESI 350
Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 46/146 (32%), Positives = 72/146 (49%), Gaps = 14/146 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
+ L NLT+ + +I+ D G L+ L ++HN L + PG + L
Sbjct 119 MEQLENLTLA----RGVVSIDRDTFSGFLNLKRLTIEHNKL-----NLQPGT----FEAL 165
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
S+L L L NG +EI +F L L+ + L N++ +L A FN SL+ LNL+ N
Sbjct 166 SNLTYLGLVYNGLNEIQPGLFDGLESLEALSLSYNDIKSLSAGSFNGLSSLRMLNLRVNK 225
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPF 647
I S + F + + L+ L++ NPF
Sbjct 226 IESFDANTFA-SLKELSRLEITLNPF 250
Score = 37.0 bits (84), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 35/126 (28%), Positives = 60/126 (48%), Gaps = 16/126 (13%)
Query 3 QTLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPD-DLPT------NITV 55
+ L C + P CA TV + +CS LT+ PD +P+ N
Sbjct 577 KDLLCDFESADDCPKDCQCAMRLLDHTV---IVNCSGRGLTEFPDLPIPSQLHEDFNALE 633
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP-MLKVLNLQHNELSQL 114
+++ +N+L +LP N T+++++T L N+I L P +P L++++L N L +
Sbjct 634 VHVENNRLTKLP--NLTKHNEITQLYARNNSIQNLLP---HNIPSKLRIIDLSQNLLKMI 688
Query 115 SDKTFA 120
D T A
Sbjct 689 DDSTLA 694
>2o6q_A A Variable lymphocyte receptor A
Length=270
Score = 80.9 bits (198), Expect = 2e-15, Method: Compositional matrix adjust.
Identities = 63/206 (31%), Positives = 102/206 (50%), Gaps = 7/206 (3%)
Query 18 GMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQL 77
G +C+ + K +V DCS KLT +P ++P + L+L N+L LP+ F R ++L
Sbjct 9 GGVCSCNNNKNSV-----DCSSKKLTAIPSNIPADTKKLDLQSNKLSSLPSKAFHRLTKL 63
Query 78 TSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK 137
L + N + L + ++L L+ L + N+L L F NL EL L N ++
Sbjct 64 RLLYLNDNKLQTLPAGIFKELKNLETLWVTDNKLQALPIGVFDQLVNLAELRLDRNQLKS 123
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANS 197
+ F L L L +N L S G +L +L+EL L NN+++ + D +
Sbjct 124 LPPRVFDSLTKLTYLSLGYNELQSLPKGVFDKLTSLKELRLYNNQLKRVPEGAFDKL--T 181
Query 198 SLKKLELSSNQIKEFSPGCFHAIGRL 223
LK L+L +NQ+K G F ++ +L
Sbjct 182 ELKTLKLDNNQLKRVPEGAFDSLEKL 207
Score = 66.2 bits (160), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 55/185 (30%), Positives = 80/185 (43%), Gaps = 31/185 (17%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
F L L +L L++N + + + + L+ LE L + N L L PI L
Sbjct 57 FHRLTKLRLLYLNDNKLQTLPAGIFKELKNLETLWVTDNKLQAL--------PIGVFDQL 108
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
+L L L+ N +P VF L +L + LG N L +LP VF+ SLK L L N
Sbjct 109 VNLAELRLDRNQLKSLPPRVFDSLTKLTYLSLGYNELQSLPKGVFDKLTSLKELRLYNNQ 168
Query 622 ITSVE--------------------KKVFGPAFRNLTELDM---RFNPFDCTCESIAWFV 658
+ V K+V AF +L +L M + NP+DCTC I +
Sbjct 169 LKRVPEGAFDKLTELKTLKLDNNQLKRVPEGAFDSLEKLKMLQLQENPWDCTCNGIIYMA 228
Query 659 NWINE 663
W+ +
Sbjct 229 KWLKK 233
Score = 58.5 bits (140), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 51/154 (33%), Positives = 71/154 (46%), Gaps = 22/154 (14%)
Query 102 KVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
K L+LQ N+LS L K F T L L+L N +Q + F + KNL TL ++ N L +
Sbjct 40 KKLDLQSNKLSSLPSKAFHRLTKLRLLYLNDNKLQTLPAGIFKELKNLETLWVTDNKLQA 99
Query 162 TKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN----------------------SSL 199
+G QL NL EL L N++++L D +SL
Sbjct 100 LPIGVFDQLVNLAELRLDRNQLKSLPPRVFDSLTKLTYLSLGYNELQSLPKGVFDKLTSL 159
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
K+L L +NQ+K G F + L L L+N QL
Sbjct 160 KELRLYNNQLKRVPEGAFDKLTELKTLKLDNNQL 193
Score = 52.0 bits (123), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 34/106 (32%), Positives = 53/106 (50%), Gaps = 0/106 (0%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L L NQL+ LP F ++LT L +G+N + L + KL LK L L +N+L
Sbjct 110 NLAELRLDRNQLKSLPPRVFDSLTKLTYLSLGYNELQSLPKGVFDKLTSLKELRLYNNQL 169
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN 157
++ + F T L L L +N ++++ F + L L L N
Sbjct 170 KRVPEGAFDKLTELKTLKLDNNQLKRVPEGAFDSLEKLKMLQLQEN 215
Score = 40.4 bits (93), Expect = 0.063, Method: Compositional matrix adjust.
Identities = 66/266 (25%), Positives = 99/266 (37%), Gaps = 67/266 (25%)
Query 275 NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
N +D S L + ++ A +L+ L+ N + L S + H L +R L L +
Sbjct 17 NKNSVDCSSKKLTAIPSNIPADTKKLD---LQSNKLSSLPSKAFHRLTKLRLLYLNDN-- 71
Query 335 KQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLR 394
L +LP F+ LK LE L + DN + + +F L+NL L L
Sbjct 72 ----KLQTLPA---GIFKELKNLETLWVTDNKLQALPIGVFDQLVNLAELRLD------- 117
Query 395 TLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG 454
+N++ + F L L L LG NE+ Q L
Sbjct 118 ---------------------RNQLKSLPPRVFDSLTKLTYLSLGYNEL-QSLP------ 149
Query 455 LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLS 514
+ +F+ S K L+L N VP F L L L L
Sbjct 150 -KGVFDKLTSL-KELRLYNNQLKRVPE------------------GAFDKLTELKTLKLD 189
Query 515 NNNIANINDDMLEGLEKLEILDLQHN 540
NN + + + + LEKL++L LQ N
Sbjct 190 NNQLKRVPEGAFDSLEKLKMLQLQEN 215
Score = 37.4 bits (85), Expect = 0.53, Method: Compositional matrix adjust.
Identities = 26/79 (33%), Positives = 43/79 (54%), Gaps = 1/79 (1%)
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
L+L+SN +P + F L +L+++ L N L TLPA +F +L++L + N + ++
Sbjct 42 LDLQSNKLSSLPSKAFHRLTKLRLLYLNDNKLQTLPAGIFKELKNLETLWVTDNKLQALP 101
Query 627 KKVFGPAFRNLTELDMRFN 645
VF NL EL + N
Sbjct 102 IGVFD-QLVNLAELRLDRN 119
>4lxs_A A Protein toll
Length=783
Score = 84.3 bits (207), Expect = 3e-15, Method: Compositional matrix adjust.
Identities = 105/392 (27%), Positives = 186/392 (47%), Gaps = 25/392 (6%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLR----RLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
+LT +P +L T++ NL+H +LR +P+ F L S++ G N + ++ +
Sbjct 134 RLTHIPANLLTDMR--NLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFG 191
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
K+P LK LNL N+L L+ F T++ + + N I+++ ++ F N+ ++LS
Sbjct 192 KMPKLKQLNLWSNQLHNLTKHDFEGATSVLGIDIHDNGIEQLPHDVFAHLTNVTDINLSA 251
Query 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGC 216
N S G ++L E+ L NN++ L + +FAN EL QI
Sbjct 252 NLFRSLPQGLFDHNKHLNEVRLMNNRV-PLATLPSRLFANQP----EL---QILRLRAEL 303
Query 217 FHAIGRLF--GLFLNNVQLGPSLTEKLCLELANTSIR--NLSLSNSQLSTTSNTTFLGLK 272
G LF + N+ LG +L + L L + +L LSN++L+ ++ F
Sbjct 304 QSLPGDLFEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLDLSNNRLTHLPDSLF--AH 361
Query 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS 332
TNLT L L N L + D F+ L L + N ++ + S + +R+L+L +
Sbjct 362 TTNLTDLRLEDNLLTGISGDIFSNLGNLVTLVMSRNRLRTIDSRAFVSTNGLRHLHLDHN 421
Query 333 FT--KQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSF 390
+Q + L + F ++ L LN+ +N I + ++ ++ L+ L L S+
Sbjct 422 DIDLQQPLLDIMLQTQINSPFGYMHGLLTLNLRNNSIIFVYNDWKNTMLQLRELDL--SY 479
Query 391 TSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
++ +L E L+ + LH+ N+T NKI +I
Sbjct 480 NNISSLGYEDLAFLSQNRLHV-NMTHNKIRRI 510
Score = 60.1 bits (144), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 109/468 (23%), Positives = 184/468 (39%), Gaps = 55/468 (12%)
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
T +RNLS + + + L NL ++ N L + F +P+L+ L
Sbjct 144 TDMRNLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLKQLNLWS 203
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDI 367
N + +L H G +V +++ + +Q LP F L + +N+ N
Sbjct 204 NQLHNLTKHDFEGATSVLGIDIHDNGIEQ------LPH---DVFAHLTNVTDINLSANLF 254
Query 368 PGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILNLTKNKISKIESDA 426
+ +F +L + L N+ L TL + F A+ P L IL L + ++ + D
Sbjct 255 RSLPQGLFDHNKHLNEVRLMNNRVPLATLPSRLF---ANQPELQILRL-RAELQSLPGDL 310
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLM 486
F + + LG N + + L N+ + LS N+ L + FA +L L
Sbjct 311 FEHSTQITNISLGDNLL-KTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFAHTTNLTDLR 369
Query 487 LRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN----- 541
L L + S F L NL L +S N + I+ L L L HN+
Sbjct 370 LEDNLLTGI--SGDIFSNLGNLVTLVMSRNRLRTIDSRAFVSTNGLRHLHLDHNDIDLQQ 427
Query 542 -LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKD----LFELKIIDLGLN 596
L + P ++ GL LNL +N + V+ D + +L+ +DL N
Sbjct 428 PLLDIMLQTQINSPFGYMHGLL---TLNLRNNSI----IFVYNDWKNTMLQLRELDLSYN 480
Query 597 NLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP--------AFRNLTELDMRFNPFD 648
N+++L + + L L N+ + +++ P L +D+ NP
Sbjct 481 NISSLG---YEDLAFLSQNRLHVNMTHNKIRRIALPEDVXXXXXXXXXLVHVDLNDNPLV 537
Query 649 CTCESIAWFVNWINETHTNIPELSSHY-------LCNTPPHYHGFPVR 689
C C +I WF+ + H P+ S + +C+ P G PVR
Sbjct 538 CDC-TILWFIQLVRGVHK--PQYSRQFKLRTDRLVCSQPNVLEGTPVR 582
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 100/399 (25%), Positives = 165/399 (41%), Gaps = 78/399 (20%)
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF 227
+ NL L L N I+ + S D N L+ +E SN++++ G F + +L
Sbjct 144 TDMRNLSHLELRAN-IEEMPSHLFDDLEN--LESIEFGSNKLRQMPRGIFGKMPKL---- 196
Query 228 LNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN 287
+ L+L ++QL + F G T++ +D+ N +
Sbjct 197 -----------------------KQLNLWSNQLHNLTKHDFEG--ATSVLGIDIHDNGIE 231
Query 288 VVGNDSFAWLPQLEYFFLEYNNI----QHLFSHSLHGLFNVRYLNLK--------RSFTK 335
+ +D FA L + L N Q LF H+ H L VR +N + R F
Sbjct 232 QLPHDVFAHLTNVTDINLSANLFRSLPQGLFDHNKH-LNEVRLMNNRVPLATLPSRLFAN 290
Query 336 QS--------ISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
Q L SLP D F+ + ++++ DN + + + + +NL L LS
Sbjct 291 QPELQILRLRAELQSLPG--DL-FEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLDLS 347
Query 388 NSFTSLRTLTNETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
N+ L L + F AH+ L L L N ++ I D FS LG+L L + N +
Sbjct 348 NN--RLTHLPDSLF---AHTTNLTDLRLEDNLLTGISGDIFSNLGNLVTLVMSRNRL--- 399
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
R +++ + + ++L L N L L +ML+ SPF +
Sbjct 400 ------RTIDSRAFVSTNGLRHLHLDHNDIDLQQPLLDIMLQT-------QINSPFGYMH 446
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
L L+L NN+I + +D + +L LDL +NN++ L
Sbjct 447 GLLTLNLRNNSIIFVYNDWKNTMLQLRELDLSYNNISSL 485
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 65/273 (24%), Positives = 113/273 (41%), Gaps = 48/273 (18%)
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
T +++ I ++ + + +L L+L N +E+ + LEN+ I NK Q+ R
Sbjct 131 TTRRLTHIPANLLTDMRNLSHLELRANI--EEMPSHLFDDLENLESIEFGSNKLRQMPRG 188
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F +P L++L L L N+ + F+ ++ +D+ +N I + D+ L +
Sbjct 189 IFGKMPKLKQLNLWSNQLHNL--TKHDFEGATSVLGIDIHDNGIEQLPHDVFAHLTNVTD 246
Query 535 LDL----------------QHNNLARLWKHANPGG--PIYFLKGLSHLHILNLESNGFDE 576
++L +H N RL + P P L IL L +
Sbjct 247 INLSANLFRSLPQGLFDHNKHLNEVRLMNNRVPLATLPSRLFANQPELQILRLRAE-LQS 305
Query 577 IPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL------------------- 617
+P ++F+ ++ I LG N L TLPA++ +QV+L SL+L
Sbjct 306 LPGDLFEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFAHTTNL 365
Query 618 -----QKNLITSVEKKVFGPAFRNLTELDMRFN 645
+ NL+T + +F NL L M N
Sbjct 366 TDLRLEDNLLTGISGDIFS-NLGNLVTLVMSRN 397
Score = 42.0 bits (97), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 36/117 (31%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query 517 NIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDE 576
NI + D L GL++ R H P + ++ LSHL L +N +E
Sbjct 113 NITRQHLDRLHGLKRFRFT-------TRRLTHI-PANLLTDMRNLSHLE---LRAN-IEE 160
Query 577 IPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPA 633
+P +F DL L+ I+ G N L +P +F LK LNL N + ++ K F A
Sbjct 161 MPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLKQLNLWSNQLHNLTKHDFEGA 217
Score = 41.6 bits (96), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 81/326 (25%), Positives = 141/326 (43%), Gaps = 30/326 (9%)
Query 300 LEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEH 359
L+ F + H+ ++ L + N+ +L L+ A++ ++ F L+ LE
Sbjct 125 LKRFRFTTRRLTHIPANLLTDMRNLSHLELR----------ANIEEMPSHLFDDLENLES 174
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
+ N + + +F + LK L+L ++ L LT F A S L I ++ N I
Sbjct 175 IEFGSNKLRQMPRGIFGKMPKLKQLNLWSN--QLHNLTKHDFEG-ATSVLGI-DIHDNGI 230
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNS--FA 477
++ D F+ L ++ ++L N + + L + +++ E+ L N+ T S FA
Sbjct 231 EQLPHDVFAHLTNVTDINLSAN-LFRSLPQGLFDHNKHLNEVRLMNNRVPLATLPSRLFA 289
Query 478 LVPSLQRLMLRRVALKNVDSSPSP-FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILD 536
P LQ L LR + S P F+ +T + L +N + + +LE L LD
Sbjct 290 NQPELQILRLR----AELQSLPGDLFEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLD 345
Query 537 LQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L +N L L P ++L L LE N I ++F +L L + + N
Sbjct 346 LSNNRLTHL--------PDSLFAHTTNLTDLRLEDNLLTGISGDIFSNLGNLVTLVMSRN 397
Query 597 NLNTLPASVFNNQVSLKSLNLQKNLI 622
L T+ + F + L+ L+L N I
Sbjct 398 RLRTIDSRAFVSTNGLRHLHLDHNDI 423
>4lxr_A A Protein toll
Length=783
Score = 84.0 bits (206), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 102/391 (26%), Positives = 189/391 (48%), Gaps = 23/391 (6%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLR----RLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
+LT +P +L T++ NL+H +LR +P+ F L S++ G N + ++ +
Sbjct 134 RLTHIPANLLTDMR--NLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFG 191
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
K+P LK LNL N+L L+ F T++ + + N I+++ ++ F N+ ++LS
Sbjct 192 KMPKLKQLNLWSNQLHNLTKHDFEGATSVLGIDIHDNGIEQLPHDVFAHLTNVTDINLSA 251
Query 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANS-SLKKLELSSNQIKEFSPG 215
N S G ++L E+ L NN++ L + +FAN L+ L L + +++
Sbjct 252 NLFRSLPQGLFDHNKHLNEVRLMNNRV-PLATLPSRLFANQPELQILRLRA-ELQSLPGD 309
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIR--NLSLSNSQLSTTSNTTFLGLKW 273
F + + N+ LG +L + L L + +L LSN++L+ ++ F
Sbjct 310 LFEHSTQ-----ITNISLGDNLLKTLPATLLEHQVNLLSLDLSNNRLTHLPDSLF--AHT 362
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
TNLT L L N L + D F+ L L + N ++ + S + +R+L+L +
Sbjct 363 TNLTDLRLEDNLLTGISGDIFSNLGNLVTLVMSRNRLRTIDSRAFVSTNGLRHLHLDHND 422
Query 334 T--KQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT 391
+Q + L + F ++ L LN+ +N I + ++ ++ L+ L L S+
Sbjct 423 IDLQQPLLDIMLQTQINSPFGYMHGLLTLNLRNNSIIFVYNDWKNTMLQLRELDL--SYN 480
Query 392 SLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
++ +L E L+ + LH+ N+T NKI +I
Sbjct 481 NISSLGYEDLAFLSQNRLHV-NMTHNKIRRI 510
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 110/468 (24%), Positives = 185/468 (40%), Gaps = 55/468 (12%)
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
T +RNLS + + + L NL ++ N L + F +P+L+ L
Sbjct 144 TDMRNLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLKQLNLWS 203
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDI 367
N + +L H G +V +++ + +Q LP F L + +N+ N
Sbjct 204 NQLHNLTKHDFEGATSVLGIDIHDNGIEQ------LPH---DVFAHLTNVTDINLSANLF 254
Query 368 PGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILNLTKNKISKIESDA 426
+ +F +L + L N+ L TL + F A+ P L IL L + ++ + D
Sbjct 255 RSLPQGLFDHNKHLNEVRLMNNRVPLATLPSRLF---ANQPELQILRL-RAELQSLPGDL 310
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLM 486
F + + LG N + + L N+ + LS N+ L + FA +L L
Sbjct 311 FEHSTQITNISLGDNLL-KTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFAHTTNLTDLR 369
Query 487 LRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN----- 541
L L + S F L NL L +S N + I+ L L L HN+
Sbjct 370 LEDNLLTGI--SGDIFSNLGNLVTLVMSRNRLRTIDSRAFVSTNGLRHLHLDHNDIDLQQ 427
Query 542 -LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKD----LFELKIIDLGLN 596
L + P ++ GL LNL +N + V+ D + +L+ +DL N
Sbjct 428 PLLDIMLQTQINSPFGYMHGLL---TLNLRNNSI----IFVYNDWKNTMLQLRELDLSYN 480
Query 597 NLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF--------RNLTELDMRFNPFD 648
N+++L + + L L N+ + +++ P NL +D+ NP
Sbjct 481 NISSLG---YEDLAFLSQNRLHVNMTHNKIRRIALPEDVXXXXXXNNNLVHVDLNDNPLV 537
Query 649 CTCESIAWFVNWINETHTNIPELSSHY-------LCNTPPHYHGFPVR 689
C C +I WF+ + H P+ S + +C+ P G PVR
Sbjct 538 CDC-TILWFIQLVRGVHK--PQYSRQFKLRTDRLVCSQPNVLEGTPVR 582
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 100/399 (25%), Positives = 165/399 (41%), Gaps = 78/399 (20%)
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF 227
+ NL L L N I+ + S D N L+ +E SN++++ G F + +L
Sbjct 144 TDMRNLSHLELRAN-IEEMPSHLFDDLEN--LESIEFGSNKLRQMPRGIFGKMPKL---- 196
Query 228 LNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN 287
+ L+L ++QL + F G T++ +D+ N +
Sbjct 197 -----------------------KQLNLWSNQLHNLTKHDFEG--ATSVLGIDIHDNGIE 231
Query 288 VVGNDSFAWLPQLEYFFLEYNNI----QHLFSHSLHGLFNVRYLNLK--------RSFTK 335
+ +D FA L + L N Q LF H+ H L VR +N + R F
Sbjct 232 QLPHDVFAHLTNVTDINLSANLFRSLPQGLFDHNKH-LNEVRLMNNRVPLATLPSRLFAN 290
Query 336 QS--------ISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
Q L SLP D F+ + ++++ DN + + + + +NL L LS
Sbjct 291 QPELQILRLRAELQSLPG--DL-FEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLDLS 347
Query 388 NSFTSLRTLTNETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
N+ L L + F AH+ L L L N ++ I D FS LG+L L + N +
Sbjct 348 NN--RLTHLPDSLF---AHTTNLTDLRLEDNLLTGISGDIFSNLGNLVTLVMSRNRL--- 399
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
R +++ + + ++L L N L L +ML+ SPF +
Sbjct 400 ------RTIDSRAFVSTNGLRHLHLDHNDIDLQQPLLDIMLQT-------QINSPFGYMH 446
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
L L+L NN+I + +D + +L LDL +NN++ L
Sbjct 447 GLLTLNLRNNSIIFVYNDWKNTMLQLRELDLSYNNISSL 485
Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 65/273 (24%), Positives = 113/273 (41%), Gaps = 48/273 (18%)
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
T +++ I ++ + + +L L+L N +E+ + LEN+ I NK Q+ R
Sbjct 131 TTRRLTHIPANLLTDMRNLSHLELRANI--EEMPSHLFDDLENLESIEFGSNKLRQMPRG 188
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F +P L++L L L N+ + F+ ++ +D+ +N I + D+ L +
Sbjct 189 IFGKMPKLKQLNLWSNQLHNL--TKHDFEGATSVLGIDIHDNGIEQLPHDVFAHLTNVTD 246
Query 535 LDL----------------QHNNLARLWKHANPGG--PIYFLKGLSHLHILNLESNGFDE 576
++L +H N RL + P P L IL L +
Sbjct 247 INLSANLFRSLPQGLFDHNKHLNEVRLMNNRVPLATLPSRLFANQPELQILRLRAE-LQS 305
Query 577 IPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL------------------- 617
+P ++F+ ++ I LG N L TLPA++ +QV+L SL+L
Sbjct 306 LPGDLFEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFAHTTNL 365
Query 618 -----QKNLITSVEKKVFGPAFRNLTELDMRFN 645
+ NL+T + +F NL L M N
Sbjct 366 TDLRLEDNLLTGISGDIFS-NLGNLVTLVMSRN 397
Score = 42.0 bits (97), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 36/117 (31%), Positives = 53/117 (45%), Gaps = 12/117 (10%)
Query 517 NIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDE 576
NI + D L GL++ R H P + ++ LSHL L +N +E
Sbjct 113 NITRQHLDRLHGLKRFRFT-------TRRLTHI-PANLLTDMRNLSHLE---LRAN-IEE 160
Query 577 IPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPA 633
+P +F DL L+ I+ G N L +P +F LK LNL N + ++ K F A
Sbjct 161 MPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLKQLNLWSNQLHNLTKHDFEGA 217
Score = 41.2 bits (95), Expect = 0.055, Method: Compositional matrix adjust.
Identities = 81/326 (25%), Positives = 141/326 (43%), Gaps = 30/326 (9%)
Query 300 LEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEH 359
L+ F + H+ ++ L + N+ +L L+ A++ ++ F L+ LE
Sbjct 125 LKRFRFTTRRLTHIPANLLTDMRNLSHLELR----------ANIEEMPSHLFDDLENLES 174
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
+ N + + +F + LK L+L ++ L LT F A S L I ++ N I
Sbjct 175 IEFGSNKLRQMPRGIFGKMPKLKQLNLWSN--QLHNLTKHDFEG-ATSVLGI-DIHDNGI 230
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNS--FA 477
++ D F+ L ++ ++L N + + L + +++ E+ L N+ T S FA
Sbjct 231 EQLPHDVFAHLTNVTDINLSAN-LFRSLPQGLFDHNKHLNEVRLMNNRVPLATLPSRLFA 289
Query 478 LVPSLQRLMLRRVALKNVDSSPSP-FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILD 536
P LQ L LR + S P F+ +T + L +N + + +LE L LD
Sbjct 290 NQPELQILRLR----AELQSLPGDLFEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLD 345
Query 537 LQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L +N L L P ++L L LE N I ++F +L L + + N
Sbjct 346 LSNNRLTHL--------PDSLFAHTTNLTDLRLEDNLLTGISGDIFSNLGNLVTLVMSRN 397
Query 597 NLNTLPASVFNNQVSLKSLNLQKNLI 622
L T+ + F + L+ L+L N I
Sbjct 398 RLRTIDSRAFVSTNGLRHLHLDHNDI 423
>4pq8_A A DESIGNED PROTEIN OR465
Length=271
Score = 80.5 bits (197), Expect = 4e-15, Method: Compositional matrix adjust.
Identities = 59/159 (37%), Positives = 91/159 (57%), Gaps = 2/159 (1%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ LNL++NQL LP F + + LT+L++ N ++ L + ++L L LNL +N+
Sbjct 92 TNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNQ 151
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L+ L F TNLT L+L +N + + F + NL TL+LS+N L+S G +L
Sbjct 152 LTSLPQGVFERLTNLTTLNLSNNQLTSLPQGVFERLTNLTTLNLSNNQLTSLPQGVFERL 211
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
+L L LSNN++ +L + N LK L LS+NQ+
Sbjct 212 TSLTTLNLSNNQLTSLPQGVFERLTN--LKTLNLSNNQL 248
Score = 67.4 bits (163), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 59/173 (34%), Positives = 85/173 (49%), Gaps = 12/173 (7%)
Query 462 YLSYNKYLQLTRNSFALVPSLQRLM-LRRVALKNVDSSPSP---FQPLRNLTILDLSNNN 517
YL +YL L N + +L+ L L + L N P F+ L NLT L+LSNN
Sbjct 68 YLPNVRYLALGGNKLHDISALKELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQ 127
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI 577
+ ++ + E L L L+L +N L L P + L++L LNL +N +
Sbjct 128 LTSLPQGVFERLASLTTLNLSNNQLTSL--------PQGVFERLTNLTTLNLSNNQLTSL 179
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
P VF+ L L ++L N L +LP VF SL +LNL N +TS+ + VF
Sbjct 180 PQGVFERLTNLTTLNLSNNQLTSLPQGVFERLTSLTTLNLSNNQLTSLPQGVF 232
Score = 64.7 bits (156), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 58/157 (37%), Positives = 84/157 (54%), Gaps = 5/157 (3%)
Query 104 LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTK 163
LNL +N+L L F TNLT L+L +N + + F + +L TL+LS+N L+S
Sbjct 97 LNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNQLTSLP 156
Query 164 LGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
G +L NL L LSNN++ +L + N L L LS+NQ+ G F + L
Sbjct 157 QGVFERLTNLTTLNLSNNQLTSLPQGVFERLTN--LTTLNLSNNQLTSLPQGVFERLTSL 214
Query 224 FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
L L+N QL SL + + L N ++ L+LSN+QL
Sbjct 215 TTLNLSNNQL-TSLPQGVFERLTN--LKTLNLSNNQL 248
Score = 53.1 bits (126), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 69/274 (25%), Positives = 116/274 (42%), Gaps = 58/274 (21%)
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
+K + K+S++ D + L ++ + ++DI ++ + L N++YL+L
Sbjct 29 IKANLKKKSVT-------DAVTQNELNSIDQIIANNSDIKSVQGIQY--LPNVRYLALGG 79
Query 389 S----FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG 444
+ ++L+ LTN L LNL+ N++ + F L +L L+L N++
Sbjct 80 NKLHDISALKELTN----------LGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLT 129
Query 445 QELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQP 504
G +FE S L L+ N +P F+
Sbjct 130 SLPQG--------VFERLASL-TTLNLSNNQLTSLPQ------------------GVFER 162
Query 505 LRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
L NLT L+LSNN + ++ + E L L L+L +N L L P + L+ L
Sbjct 163 LTNLTTLNLSNNQLTSLPQGVFERLTNLTTLNLSNNQLTSL--------PQGVFERLTSL 214
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
LNL +N +P VF+ L LK ++L N L
Sbjct 215 TTLNLSNNQLTSLPQGVFERLTNLKTLNLSNNQL 248
Score = 52.8 bits (125), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 53/100 (53%), Gaps = 1/100 (1%)
Query 555 IYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKS 614
I LK L++L LNL +N + +P VF+ L L ++L N L +LP VF SL +
Sbjct 85 ISALKELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTT 144
Query 615 LNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
LNL N +TS+ + VF NLT L++ N + +
Sbjct 145 LNLSNNQLTSLPQGVF-ERLTNLTTLNLSNNQLTSLPQGV 183
Score = 50.4 bits (119), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 73/223 (33%), Positives = 104/223 (47%), Gaps = 48/223 (22%)
Query 170 LENLQELLLSNNK---IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGL 226
L N++ L L NK I ALK EL ++L L LS+NQ++ G F + L L
Sbjct 69 LPNVRYLALGGNKLHDISALK--EL-----TNLGWLNLSNNQLETLPQGVFEKLTNLTTL 121
Query 227 FLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL 286
L+N QL SL + + LA S+ L+LSN+QL++ F + TNLT L+LS
Sbjct 122 NLSNNQL-TSLPQGVFERLA--SLTTLNLSNNQLTSLPQGVFE--RLTNLTTLNLS---- 172
Query 287 NVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKI 346
N+ LPQ + L N+ LNL + L SLP+
Sbjct 173 ----NNQLTSLPQGVF----------------ERLTNLTTLNLSNN------QLTSLPQ- 205
Query 347 DDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
F+ L L LN+ +N + + +F L NLK L+LSN+
Sbjct 206 --GVFERLTSLTTLNLSNNQLTSLPQGVFERLTNLKTLNLSNN 246
>7e5b_A A Repebody (Rb-B7)
Length=266
Score = 79.3 bits (194), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 62/185 (34%), Positives = 91/185 (49%), Gaps = 13/185 (7%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P++++LML R L ++ S + L NLT L L NN + ++ + + + L L+ L L
Sbjct 63 LPNVRKLMLPRNKLHDI----SALKELTNLTYLKLHNNQLQSLPNGVFDKLTNLKELSLL 118
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P G L++L LNL N +P VF L L ++L N L
Sbjct 119 FNQLQSL-----PDG---VFDKLTNLTYLNLAHNQLQSLPDGVFDKLTNLTYLNLAHNQL 170
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L L +N + SV VF +L + + NP+DCTC I
Sbjct 171 QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRNLS 229
Query 659 NWINE 663
WIN+
Sbjct 230 EWINK 234
Score = 67.4 bits (163), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 50/131 (38%), Positives = 66/131 (50%), Gaps = 0/131 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T L L +NQL+ LP F + + L L + FN + L + KL L LNL HN+
Sbjct 86 TNLTYLKLHNNQLQSLPNGVFDKLTNLKELSLLFNQLQSLPDGVFDKLTNLTYLNLAHNQ 145
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L D F TNLT L+L N +Q + F K L L L N L S G +L
Sbjct 146 LQSLPDGVFDKLTNLTYLNLAHNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL 205
Query 171 ENLQELLLSNN 181
+LQ + L +N
Sbjct 206 TSLQYIWLHDN 216
Score = 58.5 bits (140), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 59/187 (32%), Positives = 90/187 (48%), Gaps = 5/187 (3%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L + N +
Sbjct 43 SIDQIIANNSDIKSVQGIQYLP-NVRKLMLPRNKLHDISA--LKELTNLTYLKLHNNQLQ 99
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L+L N+L L D F TNLT L+L N +Q + + F K N
Sbjct 100 SLPNGVFDKLTNLKELSLLFNQLQSLPDGVFDKLTNLTYLNLAHNQLQSLPDGVFDKLTN 159
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
L L+L+HN L S G +L L++L L N+++++ D +SL+ + L N
Sbjct 160 LTYLNLAHNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL--TSLQYIWLHDNP 217
Query 209 IKEFSPG 215
PG
Sbjct 218 WDCTCPG 224
Score = 41.2 bits (95), Expect = 0.033, Method: Compositional matrix adjust.
Identities = 47/140 (34%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L L NN++Q+L + D N LK+L L NQ++ G F + L L L
Sbjct 84 ELTNLTYLKLHNNQLQSLPNGVFDKLTN--LKELSLLFNQLQSLPDGVFDKLTNLTYLNL 141
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
+ QL SL + + +L N + L+L+++QL + F K T L L L N L
Sbjct 142 AHNQLQ-SLPDGVFDKLTNLTY--LNLAHNQLQSLPEGVF--DKLTQLKDLRLYQNQLKS 196
Query 289 VGNDSFAWLPQLEYFFLEYN 308
V + F L L+Y +L N
Sbjct 197 VPDGVFDRLTSLQYIWLHDN 216
Score = 37.7 bits (86), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 50/188 (27%), Positives = 82/188 (44%), Gaps = 19/188 (10%)
Query 249 SIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
SI + +NS + + +L N+ L L N L+ + + L L Y L N
Sbjct 43 SIDQIIANNSDIKSVQGIQYL----PNVRKLMLPRNKLHDIS--ALKELTNLTYLKLHNN 96
Query 309 NIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIP 368
+Q L + L N++ L+L + L SLP D F L L +LN+ N +
Sbjct 97 QLQSLPNGVFDKLTNLKELSLLFN------QLQSLP---DGVFDKLTNLTYLNLAHNQLQ 147
Query 369 GIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFS 428
+ +F L NL YL+L+++ L++L F L L L L +N++ + F
Sbjct 148 SLPDGVFDKLTNLTYLNLAHN--QLQSLPEGVFDKLTQ--LKDLRLYQNQLKSVPDGVFD 203
Query 429 WLGHLEVL 436
L L+ +
Sbjct 204 RLTSLQYI 211
>7e5b_B B Repebody (Rb-B7)
Length=266
Score = 79.3 bits (194), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 62/185 (34%), Positives = 91/185 (49%), Gaps = 13/185 (7%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P++++LML R L ++ S + L NLT L L NN + ++ + + + L L+ L L
Sbjct 63 LPNVRKLMLPRNKLHDI----SALKELTNLTYLKLHNNQLQSLPNGVFDKLTNLKELSLL 118
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P G L++L LNL N +P VF L L ++L N L
Sbjct 119 FNQLQSL-----PDG---VFDKLTNLTYLNLAHNQLQSLPDGVFDKLTNLTYLNLAHNQL 170
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L L +N + SV VF +L + + NP+DCTC I
Sbjct 171 QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRNLS 229
Query 659 NWINE 663
WIN+
Sbjct 230 EWINK 234
Score = 67.4 bits (163), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 50/131 (38%), Positives = 66/131 (50%), Gaps = 0/131 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T L L +NQL+ LP F + + L L + FN + L + KL L LNL HN+
Sbjct 86 TNLTYLKLHNNQLQSLPNGVFDKLTNLKELSLLFNQLQSLPDGVFDKLTNLTYLNLAHNQ 145
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L D F TNLT L+L N +Q + F K L L L N L S G +L
Sbjct 146 LQSLPDGVFDKLTNLTYLNLAHNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL 205
Query 171 ENLQELLLSNN 181
+LQ + L +N
Sbjct 206 TSLQYIWLHDN 216
Score = 58.5 bits (140), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 59/187 (32%), Positives = 90/187 (48%), Gaps = 5/187 (3%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L + N +
Sbjct 43 SIDQIIANNSDIKSVQGIQYLP-NVRKLMLPRNKLHDISA--LKELTNLTYLKLHNNQLQ 99
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L+L N+L L D F TNLT L+L N +Q + + F K N
Sbjct 100 SLPNGVFDKLTNLKELSLLFNQLQSLPDGVFDKLTNLTYLNLAHNQLQSLPDGVFDKLTN 159
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
L L+L+HN L S G +L L++L L N+++++ D +SL+ + L N
Sbjct 160 LTYLNLAHNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL--TSLQYIWLHDNP 217
Query 209 IKEFSPG 215
PG
Sbjct 218 WDCTCPG 224
Score = 41.2 bits (95), Expect = 0.034, Method: Compositional matrix adjust.
Identities = 47/140 (34%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L L NN++Q+L + D N LK+L L NQ++ G F + L L L
Sbjct 84 ELTNLTYLKLHNNQLQSLPNGVFDKLTN--LKELSLLFNQLQSLPDGVFDKLTNLTYLNL 141
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
+ QL SL + + +L N + L+L+++QL + F K T L L L N L
Sbjct 142 AHNQLQ-SLPDGVFDKLTNLTY--LNLAHNQLQSLPEGVF--DKLTQLKDLRLYQNQLKS 196
Query 289 VGNDSFAWLPQLEYFFLEYN 308
V + F L L+Y +L N
Sbjct 197 VPDGVFDRLTSLQYIWLHDN 216
Score = 37.7 bits (86), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 50/188 (27%), Positives = 82/188 (44%), Gaps = 19/188 (10%)
Query 249 SIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
SI + +NS + + +L N+ L L N L+ + + L L Y L N
Sbjct 43 SIDQIIANNSDIKSVQGIQYL----PNVRKLMLPRNKLHDIS--ALKELTNLTYLKLHNN 96
Query 309 NIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIP 368
+Q L + L N++ L+L + L SLP D F L L +LN+ N +
Sbjct 97 QLQSLPNGVFDKLTNLKELSLLFN------QLQSLP---DGVFDKLTNLTYLNLAHNQLQ 147
Query 369 GIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFS 428
+ +F L NL YL+L+++ L++L F L L L L +N++ + F
Sbjct 148 SLPDGVFDKLTNLTYLNLAHN--QLQSLPEGVFDKLTQ--LKDLRLYQNQLKSVPDGVFD 203
Query 429 WLGHLEVL 436
L L+ +
Sbjct 204 RLTSLQYI 211
>4qxf_A A Leucine-rich repeat-containing G-protein coupled receptor
4, Variable lymphocyte receptor B
Length=301
Score = 80.1 bits (196), Expect = 8e-15, Method: Compositional matrix adjust.
Identities = 77/252 (31%), Positives = 114/252 (45%), Gaps = 14/252 (6%)
Query 20 LCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTS 79
LCA+ + C V DCS LT VP+ L L+++ N + +LP F + L
Sbjct 4 LCAAPCS-CDGDRRV-DCSGKGLTAVPEGLSAFTQALDISMNNITQLPEGAFKNFPFLEE 61
Query 80 LDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
L + N +S + P+ L LKVL LQ+N+L + + + L L L +N I +
Sbjct 62 LQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVP 121
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SS 198
+ F L L L N L+ + L LQ L L+ NKI ++ F N SS
Sbjct 122 EDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFA---FTNLSS 178
Query 199 LKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLG--PSLTEKLCLELANTSIRNLSLS 256
L L L +N+I+ S CF + L L LN LG P + L S++ L+L
Sbjct 179 LVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKAL------PSLKELALD 232
Query 257 NSQLSTTSNTTF 268
+QL + + F
Sbjct 233 TNQLKSVPDGIF 244
Score = 75.9 bits (185), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 83/334 (25%), Positives = 135/334 (40%), Gaps = 92/334 (28%)
Query 332 SFTKQ-SISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSF 390
+FT+ IS+ ++ ++ + +F+ LE L + ND+ I +GL LK L+L N+
Sbjct 33 AFTQALDISMNNITQLPEGAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNN- 91
Query 391 TSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQ 450
L+T+ +E L S L L L N I+ + D+F
Sbjct 92 -QLKTVPSEAIRGL--SALQSLRLDANHITSVPEDSF----------------------- 125
Query 451 EWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPS-PFQPLRNLT 509
GL + ++L N ++ + + +P+LQ L L AL + S P F L +L
Sbjct 126 --EGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTL---ALNKISSIPDFAFTNLSSLV 180
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L NN I +++ +GL+ LE LDL +NNL
Sbjct 181 VLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLG-------------------------- 214
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
E P + K L LK + L N L ++P +F+ SL+ + L
Sbjct 215 ------EFP-QAIKALPSLKELALDTNQLKSVPDGIFDRLTSLQKIWLHT---------- 257
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
NP+DC+C I + W+N+
Sbjct 258 ---------------NPWDCSCPRIDYLSRWLNK 276
Score = 62.8 bits (151), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 60/224 (27%), Positives = 107/224 (48%), Gaps = 21/224 (9%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK--- 335
LD+S NN+ + +F P LE L N++ + +L GL ++ L L+ + K
Sbjct 38 LDISMNNITQLPEGAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 97
Query 336 ----------QSISLAS--LPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
QS+ L + + + + SF+ L L HL ++DN + + + + L L+
Sbjct 98 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 157
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L+L+ + ++ + F +L S L +L+L NKI + F L +LE LDL N +
Sbjct 158 LTLA--LNKISSIPDFAFTNL--SSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNL 213
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
G+ Q + L ++ E+ L N+ + F + SLQ++ L
Sbjct 214 GE--FPQAIKALPSLKELALDTNQLKSVPDGIFDRLTSLQKIWL 255
Score = 53.1 bits (126), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 43/137 (31%), Positives = 68/137 (50%), Gaps = 11/137 (8%)
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
++ L+L N+QL T + GL + L L L N++ V DSF L QL + +L+ N+
Sbjct 83 LKVLTLQNNQLKTVPSEAIRGL--SALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNS 140
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
+ + H L L ++ L L +L + I DF+F L L L++ +N I
Sbjct 141 LTEVPVHPLSNLPTLQALTL---------ALNKISSIPDFAFTNLSSLVVLHLHNNKIRS 191
Query 370 IKSNMFTGLINLKYLSL 386
+ + F GL NL+ L L
Sbjct 192 LSQHCFDGLDNLETLDL 208
Score = 47.4 bits (111), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 55/192 (29%), Positives = 95/192 (49%), Gaps = 15/192 (8%)
Query 139 KNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSS 198
KN PF+++ L L+ N LS L+ L+ L L NN+++ + SE I S+
Sbjct 54 KNFPFLEE-----LQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEA--IRGLSA 106
Query 199 LKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNLSLSN 257
L+ L L +N I F + +L L+L++ SLTE L+N +++ L+L+
Sbjct 107 LQSLRLDANHITSVPEDSFEGLVQLRHLWLDDN----SLTEVPVHPLSNLPTLQALTLAL 162
Query 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
+++S+ + F L ++L +L L N + + F L LE L YNN+ F +
Sbjct 163 NKISSIPDFAFTNL--SSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGE-FPQA 219
Query 318 LHGLFNVRYLNL 329
+ L +++ L L
Sbjct 220 IKALPSLKELAL 231
>4qxf_B B Leucine-rich repeat-containing G-protein coupled receptor
4, Variable lymphocyte receptor B
Length=301
Score = 79.7 bits (195), Expect = 9e-15, Method: Compositional matrix adjust.
Identities = 77/252 (31%), Positives = 114/252 (45%), Gaps = 14/252 (6%)
Query 20 LCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTS 79
LCA+ + C V DCS LT VP+ L L+++ N + +LP F + L
Sbjct 4 LCAAPCS-CDGDRRV-DCSGKGLTAVPEGLSAFTQALDISMNNITQLPEGAFKNFPFLEE 61
Query 80 LDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
L + N +S + P+ L LKVL LQ+N+L + + + L L L +N I +
Sbjct 62 LQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVP 121
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SS 198
+ F L L L N L+ + L LQ L L+ NKI ++ F N SS
Sbjct 122 EDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFA---FTNLSS 178
Query 199 LKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLG--PSLTEKLCLELANTSIRNLSLS 256
L L L +N+I+ S CF + L L LN LG P + L S++ L+L
Sbjct 179 LVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKAL------PSLKELALD 232
Query 257 NSQLSTTSNTTF 268
+QL + + F
Sbjct 233 TNQLKSVPDGIF 244
Score = 75.9 bits (185), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 83/334 (25%), Positives = 135/334 (40%), Gaps = 92/334 (28%)
Query 332 SFTKQ-SISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSF 390
+FT+ IS+ ++ ++ + +F+ LE L + ND+ I +GL LK L+L N+
Sbjct 33 AFTQALDISMNNITQLPEGAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNN- 91
Query 391 TSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQ 450
L+T+ +E L S L L L N I+ + D+F
Sbjct 92 -QLKTVPSEAIRGL--SALQSLRLDANHITSVPEDSF----------------------- 125
Query 451 EWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPS-PFQPLRNLT 509
GL + ++L N ++ + + +P+LQ L L AL + S P F L +L
Sbjct 126 --EGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTL---ALNKISSIPDFAFTNLSSLV 180
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L NN I +++ +GL+ LE LDL +NNL
Sbjct 181 VLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLG-------------------------- 214
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
E P + K L LK + L N L ++P +F+ SL+ + L
Sbjct 215 ------EFP-QAIKALPSLKELALDTNQLKSVPDGIFDRLTSLQKIWLHT---------- 257
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
NP+DC+C I + W+N+
Sbjct 258 ---------------NPWDCSCPRIDYLSRWLNK 276
Score = 62.8 bits (151), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 60/224 (27%), Positives = 107/224 (48%), Gaps = 21/224 (9%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK--- 335
LD+S NN+ + +F P LE L N++ + +L GL ++ L L+ + K
Sbjct 38 LDISMNNITQLPEGAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVP 97
Query 336 ----------QSISLAS--LPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
QS+ L + + + + SF+ L L HL ++DN + + + + L L+
Sbjct 98 SEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQA 157
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L+L+ + ++ + F +L S L +L+L NKI + F L +LE LDL N +
Sbjct 158 LTLA--LNKISSIPDFAFTNL--SSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNL 213
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
G+ Q + L ++ E+ L N+ + F + SLQ++ L
Sbjct 214 GE--FPQAIKALPSLKELALDTNQLKSVPDGIFDRLTSLQKIWL 255
Score = 53.1 bits (126), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 43/137 (31%), Positives = 68/137 (50%), Gaps = 11/137 (8%)
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
++ L+L N+QL T + GL + L L L N++ V DSF L QL + +L+ N+
Sbjct 83 LKVLTLQNNQLKTVPSEAIRGL--SALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNS 140
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
+ + H L L ++ L L +L + I DF+F L L L++ +N I
Sbjct 141 LTEVPVHPLSNLPTLQALTL---------ALNKISSIPDFAFTNLSSLVVLHLHNNKIRS 191
Query 370 IKSNMFTGLINLKYLSL 386
+ + F GL NL+ L L
Sbjct 192 LSQHCFDGLDNLETLDL 208
Score = 47.0 bits (110), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 55/192 (29%), Positives = 95/192 (49%), Gaps = 15/192 (8%)
Query 139 KNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSS 198
KN PF+++ L L+ N LS L+ L+ L L NN+++ + SE I S+
Sbjct 54 KNFPFLEE-----LQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEA--IRGLSA 106
Query 199 LKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNLSLSN 257
L+ L L +N I F + +L L+L++ SLTE L+N +++ L+L+
Sbjct 107 LQSLRLDANHITSVPEDSFEGLVQLRHLWLDDN----SLTEVPVHPLSNLPTLQALTLAL 162
Query 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
+++S+ + F L ++L +L L N + + F L LE L YNN+ F +
Sbjct 163 NKISSIPDFAFTNL--SSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGE-FPQA 219
Query 318 LHGLFNVRYLNL 329
+ L +++ L L
Sbjct 220 IKALPSLKELAL 231
>4psj_A A OR464
Length=271
Score = 79.0 bits (193), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 61/173 (35%), Positives = 93/173 (54%), Gaps = 2/173 (1%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ LNL+ N++ +LP F + LT L++ N I+ L L + L L LNL +N+
Sbjct 92 TNLGWLNLSSNKIEKLPQGLFESLTTLTQLNLSNNQITSLPQGLFESLASLTQLNLSNNQ 151
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
++ L F TNLT+L+L +N I + F NL L+LS+N ++S G L
Sbjct 152 ITSLPQGLFESLTNLTQLNLSNNQITSLPQGLFESLTNLTQLNLSNNQITSLPQGLFESL 211
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
+L +L LSNN+I +L + N LK+L LS NQI+ G ++ +L
Sbjct 212 TSLTQLNLSNNQITSLPQGLFESLTN--LKQLNLSGNQIQSLPQGLHESLTQL 262
Score = 62.4 bits (150), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 70/192 (36%), Positives = 101/192 (53%), Gaps = 9/192 (5%)
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
Q LP ++ LNL N+L +S TNL L+L SN I+K+ F L L+L
Sbjct 66 IQYLPNVRQLNLGGNKLHDIS--ALKELTNLGWLNLSSNKIEKLPQGLFESLTTLTQLNL 123
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
S+N ++S G L +L +L LSNN+I +L + N L +L LS+NQI
Sbjct 124 SNNQITSLPQGLFESLASLTQLNLSNNQITSLPQGLFESLTN--LTQLNLSNNQITSLPQ 181
Query 215 GCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWT 274
G F ++ L L L+N Q+ SL + L L TS+ L+LSN+Q+++ F L T
Sbjct 182 GLFESLTNLTQLNLSNNQI-TSLPQGLFESL--TSLTQLNLSNNQITSLPQGLFESL--T 236
Query 275 NLTMLDLSYNNL 286
NL L+LS N +
Sbjct 237 NLKQLNLSGNQI 248
Score = 62.0 bits (149), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 47/144 (33%), Positives = 75/144 (52%), Gaps = 9/144 (6%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
F+ L LT L+LSNN I ++ + E L L L+L +N + L P + L
Sbjct 112 FESLTTLTQLNLSNNQITSLPQGLFESLASLTQLNLSNNQITSL--------PQGLFESL 163
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
++L LNL +N +P +F+ L L ++L N + +LP +F + SL LNL N
Sbjct 164 TNLTQLNLSNNQITSLPQGLFESLTNLTQLNLSNNQITSLPQGLFESLTSLTQLNLSNNQ 223
Query 622 ITSVEKKVFGPAFRNLTELDMRFN 645
ITS+ + +F + NL +L++ N
Sbjct 224 ITSLPQGLF-ESLTNLKQLNLSGN 246
Score = 59.7 bits (143), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 64/217 (29%), Positives = 105/217 (48%), Gaps = 26/217 (12%)
Query 420 SKIES-DAFSWLGHLEVLDLGLNEIG-----QELTGQEWRGLENIFEIYLSYNKYLQLTR 473
S I+S +L ++ L+LG N++ +ELT W + LS NK +L +
Sbjct 58 SDIKSVQGIQYLPNVRQLNLGGNKLHDISALKELTNLGW--------LNLSSNKIEKLPQ 109
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSP-FQPLRNLTILDLSNNNIANINDDMLEGLEKL 532
F + +L +L L + S P F+ L +LT L+LSNN I ++ + E L L
Sbjct 110 GLFESLTTLTQLNLSN---NQITSLPQGLFESLASLTQLNLSNNQITSLPQGLFESLTNL 166
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L+L +N + L P + L++L LNL +N +P +F+ L L ++
Sbjct 167 TQLNLSNNQITSL--------PQGLFESLTNLTQLNLSNNQITSLPQGLFESLTSLTQLN 218
Query 593 LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
L N + +LP +F + +LK LNL N I S+ + +
Sbjct 219 LSNNQITSLPQGLFESLTNLKQLNLSGNQIQSLPQGL 255
Score = 58.2 bits (139), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 75/281 (27%), Positives = 123/281 (44%), Gaps = 58/281 (21%)
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
+K + K+S++ D + L ++ +N ++DI ++ + L N++ L+L
Sbjct 29 IKANLKKKSVT-------DAVTQNELNSIDQINANNSDIKSVQGIQY--LPNVRQLNLGG 79
Query 389 S----FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG 444
+ ++L+ LTN L LNL+ NKI K+ F L L L+L N+I
Sbjct 80 NKLHDISALKELTN----------LGWLNLSSNKIEKLPQGLFESLTTLTQLNLSNNQIT 129
Query 445 QELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQP 504
G +FE S + L L+ N +P Q L F+
Sbjct 130 SLPQG--------LFESLASLTQ-LNLSNNQITSLP--QGL----------------FES 162
Query 505 LRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
L NLT L+LSNN I ++ + E L L L+L +N + L P + L+ L
Sbjct 163 LTNLTQLNLSNNQITSLPQGLFESLTNLTQLNLSNNQITSL--------PQGLFESLTSL 214
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASV 605
LNL +N +P +F+ L LK ++L N + +LP +
Sbjct 215 TQLNLSNNQITSLPQGLFESLTNLKQLNLSGNQIQSLPQGL 255
Score = 57.0 bits (136), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 55/159 (35%), Positives = 84/159 (53%), Gaps = 5/159 (3%)
Query 104 LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTK 163
LNL N++ +L F T LT+L+L +N I + F +L L+LS+N ++S
Sbjct 97 LNLSSNKIEKLPQGLFESLTTLTQLNLSNNQITSLPQGLFESLASLTQLNLSNNQITSLP 156
Query 164 LGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
G L NL +L LSNN+I +L + N L +L LS+NQI G F ++ L
Sbjct 157 QGLFESLTNLTQLNLSNNQITSLPQGLFESLTN--LTQLNLSNNQITSLPQGLFESLTSL 214
Query 224 FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLST 262
L L+N Q+ SL + L L N ++ L+LS +Q+ +
Sbjct 215 TQLNLSNNQI-TSLPQGLFESLTN--LKQLNLSGNQIQS 250
Score = 52.0 bits (123), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 37/103 (36%), Positives = 58/103 (56%), Gaps = 5/103 (5%)
Query 547 KHANPGG----PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLP 602
+ N GG I LK L++L LNL SN +++P +F+ L L ++L N + +LP
Sbjct 73 RQLNLGGNKLHDISALKELTNLGWLNLSSNKIEKLPQGLFESLTTLTQLNLSNNQITSLP 132
Query 603 ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
+F + SL LNL N ITS+ + +F + NLT+L++ N
Sbjct 133 QGLFESLASLTQLNLSNNQITSLPQGLF-ESLTNLTQLNLSNN 174
Score = 48.9 bits (115), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 54/173 (31%), Positives = 79/173 (46%), Gaps = 15/173 (9%)
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKR 331
+ TNL L+LS N + + F L L L N I L L ++ LNL
Sbjct 90 ELTNLGWLNLSSNKIEKLPQGLFESLTTLTQLNLSNNQITSLPQGLFESLASLTQLNLSN 149
Query 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS-F 390
+ + SLP+ F+ L L LN+ +N I + +F L NL L+LSN+
Sbjct 150 N------QITSLPQ---GLFESLTNLTQLNLSNNQITSLPQGLFESLTNLTQLNLSNNQI 200
Query 391 TSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
TSL E+ SL LNL+ N+I+ + F L +L+ L+L N+I
Sbjct 201 TSLPQGLFESLTSLTQ-----LNLSNNQITSLPQGLFESLTNLKQLNLSGNQI 248
Score = 43.5 bits (101), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 33/94 (35%), Positives = 49/94 (52%), Gaps = 3/94 (3%)
Query 36 DCSHLKLTQVPDDL---PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
+ S+ ++T +P L TN+T LNL++NQ+ LP F + LT L++ N I+ L
Sbjct 170 NLSNNQITSLPQGLFESLTNLTQLNLSNNQITSLPQGLFESLTSLTQLNLSNNQITSLPQ 229
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLT 126
L + L LK LNL N++ L T LT
Sbjct 230 GLFESLTNLKQLNLSGNQIQSLPQGLHESLTQLT 263
>3zyo_A A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4B
Length=411
Score = 80.1 bits (196), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 80/288 (28%), Positives = 127/288 (44%), Gaps = 34/288 (12%)
Query 23 SSTTKCTVSHEVAD--CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSL 80
S C+ S+ + C+ +L +VP +P N LNL N ++ + F L L
Sbjct 5 SCPAACSCSNXXSRVICTRRELAEVPASIPVNTRYLNLQENSIQVIRTDTFKHLRHLEIL 64
Query 81 DVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKN 140
+ N + K+E LP L L L N L+ + + F + + L EL L +N I+ I +
Sbjct 65 QLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPS 124
Query 141 NPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLK 200
F + +L LDL L + ++ E L L N + LK + ++ A L+
Sbjct 125 YAFNRVPSLRRLDLGE--LKRLEYISEAAFEGLVNLRYLNLGMCNLK-DIPNLTALVRLE 181
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+LELS N++ PG F + TS+R L L ++Q+
Sbjct 182 ELELSGNRLDLIRPGSFQGL---------------------------TSLRKLWLMHAQV 214
Query 261 STTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
+T F LK +L L+LS+NNL + +D F L +LE L +N
Sbjct 215 ATIERNAFDDLK--SLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHN 260
Score = 78.2 bits (191), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 95/325 (29%), Positives = 144/325 (44%), Gaps = 48/325 (15%)
Query 379 INLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
+N +YL+L NS +RT +TF L H L IL L+KN + KIE AF+ L L L+
Sbjct 35 VNTRYLNLQENSIQVIRT---DTFKHLRH--LEILQLSKNLVRKIEVGAFNGLPSLNTLE 89
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS 497
L N + T Q + L + E++L N + +F VPSL+RL L LK ++
Sbjct 90 LFDNRLTTVPT-QAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGE--LKRLEY 146
Query 498 -SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY 556
S + F+ L NL L+L N+ +I + L L +LE L+L N L
Sbjct 147 ISEAAFEGLVNLRYLNLGMCNLKDIPN--LTALVRLEELELSGNRL-------------- 190
Query 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
D I F+ L L+ + L + T+ + F++ SL+ LN
Sbjct 191 ------------------DLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELN 232
Query 617 LQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYL 676
L N + S+ +F P R L + + NP+ C C+ + W W+ ET + +
Sbjct 233 LSHNNLMSLPHDLFTPLHR-LERVHLNHNPWHCNCD-VLWLSWWLKETVPSXXXXCAR-- 288
Query 677 CNTPPHYHGFPVRLFDTSSCKDSAP 701
C+ P G + D S AP
Sbjct 289 CHAPAGLKGRYIGELDQSHFTCYAP 313
Score = 58.2 bits (139), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 71/231 (31%), Positives = 107/231 (46%), Gaps = 33/231 (14%)
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
N RYLNL+ + S+ I +F+ L+ LE L + N + I+ F GL +L
Sbjct 36 NTRYLNLQEN---------SIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLN 86
Query 383 YLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE 442
L L ++ L T+ + F L S L L L N I I S AF+ + L LDLG +
Sbjct 87 TLELFDN--RLTTVPTQAFEYL--SKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELK 142
Query 443 IGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS---- 498
+ ++ + GL N+ +YL L + +P+L L V L+ ++ S
Sbjct 143 RLEYISEAAFEGLVNL--------RYLNLGMCNLKDIPNLTAL----VRLEELELSGNRL 190
Query 499 ----PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
P FQ L +L L L + +A I + + L+ LE L+L HNNL L
Sbjct 191 DLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSL 241
Score = 52.4 bits (124), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 69/274 (25%), Positives = 116/274 (42%), Gaps = 41/274 (15%)
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
+L++ + N L+L NSIQ I+ + F ++L L LS N + ++G L +
Sbjct 25 ELAEVPASIPVNTRYLNLQENSIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPS 84
Query 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ 232
L L L +N++ + ++ + S L++L L +N I+ F+ + L L L ++
Sbjct 85 LNTLELFDNRLTTVPTQAFEYL--SKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELK 142
Query 233 LGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGND 292
+L S F GL NL L+L NL + N
Sbjct 143 --------------------------RLEYISEAAFEGL--VNLRYLNLGMCNLKDIPN- 173
Query 293 SFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQ 352
L +LE L N + + S GL ++R L L A + I+ +F
Sbjct 174 -LTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMH---------AQVATIERNAFD 223
Query 353 WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
LK LE LN+ N++ + ++FT L L+ + L
Sbjct 224 DLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHL 257
Score = 51.6 bits (122), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 66/268 (25%), Positives = 115/268 (43%), Gaps = 45/268 (17%)
Query 275 NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
N L+L N++ V+ D+F L LE L N ++ + + +GL ++ L L F
Sbjct 36 NTRYLNLQENSIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLEL---FD 92
Query 335 KQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLR 394
+ L + +F++L L L + +N I I S F + +L+ L L
Sbjct 93 NR------LTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGE------ 140
Query 395 TLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ--ELTGQEW 452
++ I AF L +L L+LG+ + LT
Sbjct 141 ---------------------LKRLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLT---- 175
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
L + E+ LS N+ + SF + SL++L L + ++ + F L++L L+
Sbjct 176 -ALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIER--NAFDDLKSLEELN 232
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHN 540
LS+NN+ ++ D+ L +LE + L HN
Sbjct 233 LSHNNLMSLPHDLFTPLHRLERVHLNHN 260
>4r5c_A A Leucine rich repeat protein
Length=304
Score = 78.6 bits (192), Expect = 2e-14, Method: Compositional matrix adjust.
Identities = 71/210 (34%), Positives = 112/210 (53%), Gaps = 13/210 (6%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ LNL++NQL LP F + + LT+L++ N ++ L + ++L L LNL +N+
Sbjct 84 TNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSNNQ 143
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L+ L F TNLT L+L +N + + F + NL TL+LS+N L+S G +L
Sbjct 144 LTSLPQGVFERLTNLTTLNLSNNQLTSLPQGVFERLTNLTTLNLSNNQLTSLPQGVFERL 203
Query 171 ENLQELLLSNNKIQALKS-EELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
+L L LSNN I + + + LD +L L+LS+N I + S + L L L+
Sbjct 204 TSLHTLDLSNNGITDISALKNLD-----NLHTLDLSNNGITDIS--ALKNLDNLHTLDLS 256
Query 230 N-----VQLGPSLTEKLCLELANTSIRNLS 254
N + +LT L+L+N I ++S
Sbjct 257 NNGITDISALKNLTSLHTLDLSNNGITDIS 286
Score = 67.0 bits (162), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 88/321 (27%), Positives = 146/321 (45%), Gaps = 43/321 (13%)
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
+K + K+S++ D + L ++ + ++DI ++ + L N++YL+L
Sbjct 21 IKANLKKKSVT-------DAVTQNELNSIDQIIANNSDIKSVQGIQY--LPNVRYLALGG 71
Query 389 S----FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG 444
+ ++L+ LTN L LNL+ N++ + F L +L L+L N++
Sbjct 72 NKLHDISALKELTN----------LGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLT 121
Query 445 QELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQP 504
G R L ++ + LS N+ L + F + +L L L L ++ F+
Sbjct 122 SLPQGVFER-LASLTTLNLSNNQLTSLPQGVFERLTNLTTLNLSNNQLTSL--PQGVFER 178
Query 505 LRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
L NLT L+LSNN + ++ + E L L LDL +N + I LK L +L
Sbjct 179 LTNLTTLNLSNNQLTSLPQGVFERLTSLHTLDLSNNGITD----------ISALKNLDNL 228
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
H L+L +NG +I K+L L +DL N + + A N SL +L+L N IT
Sbjct 229 HTLDLSNNGITDI--SALKNLDNLHTLDLSNNGITDISA--LKNLTSLHTLDLSNNGITD 284
Query 625 VEKKVFGPAFRNLTELDMRFN 645
+ NL LD+R N
Sbjct 285 ISAL---KNLDNLETLDLRNN 302
Score = 58.2 bits (139), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 73/228 (32%), Positives = 105/228 (46%), Gaps = 17/228 (7%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
++L L LNL +N+L L F TNLT L+L +N + + F + +L TL+LS
Sbjct 81 KELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLS 140
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L+S G +L NL L LSNN++ +L + N L L LS+NQ+ G
Sbjct 141 NNQLTSLPQGVFERLTNLTTLNLSNNQLTSLPQGVFERLTN--LTTLNLSNNQLTSLPQG 198
Query 216 CFHAIGRLFGLFLNN-----VQLGPSLTEKLCLELANTSIRNLS-------LSNSQLSTT 263
F + L L L+N + +L L+L+N I ++S L LS
Sbjct 199 VFERLTSLHTLDLSNNGITDISALKNLDNLHTLDLSNNGITDISALKNLDNLHTLDLSNN 258
Query 264 SNTTFLGLK-WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNI 310
T LK T+L LDLS N + + + L LE L N I
Sbjct 259 GITDISALKNLTSLHTLDLSNNGITDIS--ALKNLDNLETLDLRNNGI 304
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 82/269 (30%), Positives = 116/269 (43%), Gaps = 48/269 (18%)
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKR 331
+ TNL L+LS N L + F L L L N + L L ++ LNL
Sbjct 82 ELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTTLNLSN 141
Query 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT 391
+ L SLP+ F+ L L LN+ +N + + +F L NL L+LSN+
Sbjct 142 N------QLTSLPQ---GVFERLTNLTTLNLSNNQLTSLPQGVFERLTNLTTLNLSNN-- 190
Query 392 SLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
L +L F L + LH L+L+ N I+ I A L +L LDL N I
Sbjct 191 QLTSLPQGVFERL--TSLHTLDLSNNGITDIS--ALKNLDNLHTLDLSNNGITDI---SA 243
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
+ L+N+ + LS N ++ ALKN+ S L L
Sbjct 244 LKNLDNLHTLDLSNNGITDIS------------------ALKNLTS----------LHTL 275
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHN 540
DLSNN I +I L+ L+ LE LDL++N
Sbjct 276 DLSNNGITDI--SALKNLDNLETLDLRNN 302
Score = 51.6 bits (122), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 36/100 (36%), Positives = 53/100 (53%), Gaps = 1/100 (1%)
Query 555 IYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKS 614
I LK L++L LNL +N + +P VF+ L L ++L N L +LP VF SL +
Sbjct 77 ISALKELTNLGWLNLSNNQLETLPQGVFEKLTNLTTLNLSNNQLTSLPQGVFERLASLTT 136
Query 615 LNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
LNL N +TS+ + VF NLT L++ N + +
Sbjct 137 LNLSNNQLTSLPQGVF-ERLTNLTTLNLSNNQLTSLPQGV 175
>4po4_A A Lampetra planeri VLRC
Length=221
Score = 76.6 bits (187), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 61/162 (38%), Positives = 78/162 (48%), Gaps = 1/162 (1%)
Query 20 LCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTS 79
LC S K S E DCS KLT VP +PT+ L L +NQL +P F ++LT
Sbjct 10 LCTCSN-KTESSPETVDCSSKKLTTVPTGIPTSTEKLQLNYNQLTGIPPTAFQGLTKLTY 68
Query 80 LDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
L++ N + L + +L L L L N+L L + F TNLT L+L N +Q I
Sbjct 69 LNLDSNQLQYLPVGVFDQLKNLNELRLDFNKLKSLPPRVFDRLTNLTALYLEYNQLQSIP 128
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
F K NL TL L N L S G L ++ L L NN
Sbjct 129 KGVFDKLVNLETLWLRENKLQSVPDGAFDSLTKVEMLQLHNN 170
Score = 63.5 bits (153), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 55/191 (29%), Positives = 83/191 (43%), Gaps = 35/191 (18%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
+D S+ + + + EKL+ L +N L G P +GL+ L LNL+
Sbjct 24 VDCSSKKLTTVPTGIPTSTEKLQ---LNYNQLT--------GIPPTAFQGLTKLTYLNLD 72
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
SN +PV VF L L + L N L +LP VF+ +L +L L+ N + S+ K VF
Sbjct 73 SNQLQYLPVGVFDQLKNLNELRLDFNKLKSLPPRVFDRLTNLTALYLEYNQLQSIPKGVF 132
Query 631 GP--------------------AFRNLTELDM---RFNPFDCTCESIAWFVNWINETHTN 667
AF +LT+++M NP+DC C I + +I +
Sbjct 133 DKLVNLETLWLRENKLQSVPDGAFDSLTKVEMLQLHNNPWDCACSDIIYLRTFIAKNTDK 192
Query 668 IPELSSHYLCN 678
I + S CN
Sbjct 193 ISGMESAQ-CN 202
Score = 38.5 bits (88), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 41/133 (31%), Positives = 61/133 (46%), Gaps = 5/133 (4%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
+S +KL+L+ NQ+ P F + +L L L++ QL L + +L N + L L
Sbjct 40 TSTEKLQLNYNQLTGIPPTAFQGLTKLTYLNLDSNQLQ-YLPVGVFDQLKN--LNELRLD 96
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
++L + F L TNLT L L YN L + F L LE +L N +Q +
Sbjct 97 FNKLKSLPPRVFDRL--TNLTALYLEYNQLQSIPKGVFDKLVNLETLWLRENKLQSVPDG 154
Query 317 SLHGLFNVRYLNL 329
+ L V L L
Sbjct 155 AFDSLTKVEMLQL 167
Score = 38.1 bits (87), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 43/132 (33%), Positives = 59/132 (45%), Gaps = 9/132 (7%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
T+ +L L N + I F L L+L N L +G QL+NL EL L NK
Sbjct 40 TSTEKLQLNYNQLTGIPPTAFQGLTKLTYLNLDSNQLQYLPVGVFDQLKNLNELRLDFNK 99
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL--NNVQLGP----- 235
+++L D N L L L NQ++ G F + L L+L N +Q P
Sbjct 100 LKSLPPRVFDRLTN--LTALYLEYNQLQSIPKGVFDKLVNLETLWLRENKLQSVPDGAFD 157
Query 236 SLTEKLCLELAN 247
SLT+ L+L N
Sbjct 158 SLTKVEMLQLHN 169
Score = 37.7 bits (86), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 40/159 (25%), Positives = 63/159 (40%), Gaps = 31/159 (19%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
E L + N + GI F GL L YL NL N
Sbjct 43 EKLQLNYNQLTGIPPTAFQGLTKLTYL----------------------------NLDSN 74
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + F L +L L L N++ + L + + L N+ +YL YN+ + + F
Sbjct 75 QLQYLPVGVFDQLKNLNELRLDFNKL-KSLPPRVFDRLTNLTALYLEYNQLQSIPKGVFD 133
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
+ +L+ L LR L++V F L + +L L NN
Sbjct 134 KLVNLETLWLRENKLQSVPD--GAFDSLTKVEMLQLHNN 170
>4po4_B B Lampetra planeri VLRC
Length=221
Score = 76.6 bits (187), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 61/162 (38%), Positives = 78/162 (48%), Gaps = 1/162 (1%)
Query 20 LCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTS 79
LC S K S E DCS KLT VP +PT+ L L +NQL +P F ++LT
Sbjct 10 LCTCSN-KTESSPETVDCSSKKLTTVPTGIPTSTEKLQLNYNQLTGIPPTAFQGLTKLTY 68
Query 80 LDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
L++ N + L + +L L L L N+L L + F TNLT L+L N +Q I
Sbjct 69 LNLDSNQLQYLPVGVFDQLKNLNELRLDFNKLKSLPPRVFDRLTNLTALYLEYNQLQSIP 128
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
F K NL TL L N L S G L ++ L L NN
Sbjct 129 KGVFDKLVNLETLWLRENKLQSVPDGAFDSLTKVEMLQLHNN 170
Score = 63.5 bits (153), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 55/191 (29%), Positives = 83/191 (43%), Gaps = 35/191 (18%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
+D S+ + + + EKL+ L +N L G P +GL+ L LNL+
Sbjct 24 VDCSSKKLTTVPTGIPTSTEKLQ---LNYNQLT--------GIPPTAFQGLTKLTYLNLD 72
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
SN +PV VF L L + L N L +LP VF+ +L +L L+ N + S+ K VF
Sbjct 73 SNQLQYLPVGVFDQLKNLNELRLDFNKLKSLPPRVFDRLTNLTALYLEYNQLQSIPKGVF 132
Query 631 GP--------------------AFRNLTELDM---RFNPFDCTCESIAWFVNWINETHTN 667
AF +LT+++M NP+DC C I + +I +
Sbjct 133 DKLVNLETLWLRENKLQSVPDGAFDSLTKVEMLQLHNNPWDCACSDIIYLRTFIAKNTDK 192
Query 668 IPELSSHYLCN 678
I + S CN
Sbjct 193 ISGMESAQ-CN 202
Score = 38.5 bits (88), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 41/133 (31%), Positives = 61/133 (46%), Gaps = 5/133 (4%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
+S +KL+L+ NQ+ P F + +L L L++ QL L + +L N + L L
Sbjct 40 TSTEKLQLNYNQLTGIPPTAFQGLTKLTYLNLDSNQLQ-YLPVGVFDQLKN--LNELRLD 96
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
++L + F L TNLT L L YN L + F L LE +L N +Q +
Sbjct 97 FNKLKSLPPRVFDRL--TNLTALYLEYNQLQSIPKGVFDKLVNLETLWLRENKLQSVPDG 154
Query 317 SLHGLFNVRYLNL 329
+ L V L L
Sbjct 155 AFDSLTKVEMLQL 167
Score = 38.1 bits (87), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 43/132 (33%), Positives = 59/132 (45%), Gaps = 9/132 (7%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
T+ +L L N + I F L L+L N L +G QL+NL EL L NK
Sbjct 40 TSTEKLQLNYNQLTGIPPTAFQGLTKLTYLNLDSNQLQYLPVGVFDQLKNLNELRLDFNK 99
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL--NNVQLGP----- 235
+++L D N L L L NQ++ G F + L L+L N +Q P
Sbjct 100 LKSLPPRVFDRLTN--LTALYLEYNQLQSIPKGVFDKLVNLETLWLRENKLQSVPDGAFD 157
Query 236 SLTEKLCLELAN 247
SLT+ L+L N
Sbjct 158 SLTKVEMLQLHN 169
Score = 37.7 bits (86), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 40/159 (25%), Positives = 63/159 (40%), Gaps = 31/159 (19%)
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
E L + N + GI F GL L YL NL N
Sbjct 43 EKLQLNYNQLTGIPPTAFQGLTKLTYL----------------------------NLDSN 74
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + F L +L L L N++ + L + + L N+ +YL YN+ + + F
Sbjct 75 QLQYLPVGVFDQLKNLNELRLDFNKL-KSLPPRVFDRLTNLTALYLEYNQLQSIPKGVFD 133
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
+ +L+ L LR L++V F L + +L L NN
Sbjct 134 KLVNLETLWLRENKLQSVPD--GAFDSLTKVEMLQLHNN 170
>5y3m_F B Toll-like receptor 9
Length=801
Score = 80.9 bits (198), Expect = 3e-14, Method: Compositional matrix adjust.
Identities = 95/342 (28%), Positives = 142/342 (42%), Gaps = 36/342 (11%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L++ N++ I+ MFT L L+ L LS++ S + + FV L + L +L+L+ NK+
Sbjct 455 LDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSIS-QAVNGSQFVPL--TSLRVLDLSHNKL 511
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALV 479
+F+ L LE LDL N + G G F L +YL L N +
Sbjct 512 DLYHGRSFTELPQLEALDLSYNSQPFSMQGV---GHNLSFVAQLPSLRYLSLAHNG---I 565
Query 480 PSLQRLMLRRVALKNVDSSPSP--------------FQPLRNLTILDLSNNNIANINDDM 525
S L +L+ +D S + F+ LRNL LDLS N++ +
Sbjct 566 HSRVSQKLSSASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLDLSENHLHTLLPRH 625
Query 526 LEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFK 583
L+ L K L L L+ NNLA W L L L L+L N +
Sbjct 626 LDNLPKSLRQLRLRDNNLAFFNWSS---------LTVLPRLEALDLAGNQLKALSNGSLP 676
Query 584 DLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMR 643
L+ +D+ N++ + F L LNL N + +V+ FG L LD+
Sbjct 677 PGIRLQKLDVSSNSIGFVIPGFFVRATRLIELNLSANALKTVDPSWFGSLAGTLKILDVS 736
Query 644 FNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
NP C FV+++ E +P LS C +P G
Sbjct 737 ANPLHCA--XXXAFVDFLLERQEAVPGLSRRVTCGSPGQLQG 776
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 87/327 (27%), Positives = 137/327 (42%), Gaps = 39/327 (12%)
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLMSNSIQK 137
+LD+ N + ++ E+ +L L+ L L HN +SQ ++ F T+L L L N +
Sbjct 454 TLDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSISQAVNGSQFVPLTSLRVLDLSHNKLDL 513
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQ------VQLENLQELLLSNNKIQALKSEEL 191
F + L LDLS+N + G QL +L+ L L++N I + S++L
Sbjct 514 YHGRSFTELPQLEALDLSYNSQPFSMQGVGHNLSFVAQLPSLRYLSLAHNGIHSRVSQKL 573
Query 192 DIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL----NNVQLGPSLTEKLCLELAN 247
+++SL+ L+ S N + + A G L+ F N VQL L+E L
Sbjct 574 ---SSASLRALDFSGNSLSQ-----MWAEGDLYLCFFKGLRNLVQL--DLSENHLHTLLP 623
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM------LDLSYNNLNVVGNDSFAWLPQLE 301
+ NL S QL N W++LT+ LDL+ N L + N S +L+
Sbjct 624 RHLDNLPKSLRQLRLRDNNLAF-FNWSSLTVLPRLEALDLAGNQLKALSNGSLPPGIRLQ 682
Query 302 YFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQS-----ISLASLPKIDDFSFQWLKC 356
+ N+I + + LNL + K SLA KI D S L C
Sbjct 683 KLDVSSNSIGFVIPGFFVRATRLIELNLSANALKTVDPSWFGSLAGTLKILDVSANPLHC 742
Query 357 ------LEHLNMEDNDIPGIKSNMFTG 377
++ L +PG+ + G
Sbjct 743 AXXXAFVDFLLERQEAVPGLSRRVTCG 769
Score = 52.8 bits (125), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 73/264 (28%), Positives = 123/264 (47%), Gaps = 32/264 (12%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP----------ELCQKLPM 100
T++ VL+L+HN+L +FT QL +LD+ +N+ +P +LP
Sbjct 499 TSLRVLDLSHNKLDLYHGRSFTELPQLEALDLSYNS----QPFSMQGVGHNLSFVAQLPS 554
Query 101 LKVLNLQHNEL-SQLSDKTFAFCTNLTELHLMSNSIQKIKNNP------FVKQKNLITLD 153
L+ L+L HN + S++S K + +L L NS+ ++ F +NL+ LD
Sbjct 555 LRYLSLAHNGIHSRVSQKLSS--ASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLD 612
Query 154 LSHNGLSSTKLGTQVQ--LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
LS N L T L + ++L++L L +N + L + L+ L+L+ NQ+K
Sbjct 613 LSENHL-HTLLPRHLDNLPKSLRQLRLRDNNLAFFNWSSLTVLPR--LEALDLAGNQLKA 669
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
S G RL L +++ +G + + T + L+LS + L T + F L
Sbjct 670 LSNGSLPPGIRLQKLDVSSNSIGFVIPG---FFVRATRLIELNLSANALKTVDPSWFGSL 726
Query 272 KWTNLTMLDLSYNNLNVVGNDSFA 295
T L +LD+S N L+ +F
Sbjct 727 AGT-LKILDVSANPLHCAXXXAFV 749
Score = 50.4 bits (119), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 86/284 (30%), Positives = 122/284 (43%), Gaps = 34/284 (12%)
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
+ ++ L LS++ +S N + + T+L +LDLS+N L++ SF LPQLE L Y
Sbjct 474 SRLQCLRLSHNSISQAVNGSQF-VPLTSLRVLDLSHNKLDLYHGRSFTELPQLEALDLSY 532
Query 308 NNIQHLFSHSLHGLF------NVRYLNLK----RSFTKQSISLASLPKID----DFSFQW 353
N+ H L ++RYL+L S Q +S ASL +D S W
Sbjct 533 NSQPFSMQGVGHNLSFVAQLPSLRYLSLAHNGIHSRVSQKLSSASLRALDFSGNSLSQMW 592
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
+ +L F GL NL L LS + L TL +L S L L
Sbjct 593 AEGDLYL------------CFFKGLRNLVQLDLSEN--HLHTLLPRHLDNLPKS-LRQLR 637
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
L N ++ + + L LE LDL N++ G G+ + ++ +S N +
Sbjct 638 LRDNNLAFFNWSSLTVLPRLEALDLAGNQLKALSNGSLPPGIR-LQKLDVSSNSIGFVIP 696
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRN-LTILDLSNN 516
F L L L ALK VD PS F L L ILD+S N
Sbjct 697 GFFVRATRLIELNLSANALKTVD--PSWFGSLAGTLKILDVSAN 738
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 115/422 (27%), Positives = 167/422 (40%), Gaps = 81/422 (19%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE------- 171
N+T L L+SN I + ++ FV NL L+L N GLS ++ +E
Sbjct 42 ANVTSLSLISNRIHHLHDSDFVHLSNLRVLNLKWNCPPAGLSPMHFPCRMTIEPNTFLAV 101
Query 172 -NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L+EL LS N I + + SSL L LS I P F + L L+++
Sbjct 102 PTLEELNLSYNGITTVPALP------SSLVSLSLSHTSILVLGPTHFTGLHALRFLYMDG 155
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
C + N R L ++ L LGL NLT L L YNNL V
Sbjct 156 N----------CYYM-NPCPRALEVAPGAL--------LGLG--NLTHLSLKYNNLTEVP 194
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL-------ASL 343
P L+ L YN+I L L L +R L++ + + + +
Sbjct 195 R---RLPPSLDTLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCRECPKNF 251
Query 344 PKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS 403
PK+ +F L LE L ++D+ + ++ + F GL L+ L LS +F F
Sbjct 252 PKLHPDTFSHLSRLEGLVLKDSSLYKLEKDWFRGLGRLQVLDLSENFLYDYITKTTIFND 311
Query 404 LAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN 457
L L LNL+ N K+ + +F L LE LD + G +R L N
Sbjct 312 LTQ--LRRLNLSFNYHKKVSFAHLHLASSFGSLVSLEKLD---------MHGIFFRSLTN 360
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
I T S +P LQ L L+ + S F +L +DLS+N
Sbjct 361 I-------------TLQSLTRLPKLQSLHLQLNFINQAQL--SIFGAFPSLLFVDLSDNR 405
Query 518 IA 519
I+
Sbjct 406 IS 407
Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 153/685 (22%), Positives = 248/685 (36%), Gaps = 158/685 (23%)
Query 32 HEVADCSHLKLTQVP---DDLP-TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
H DC+ L L VP P N+T L+L N++ L ++F S L
Sbjct 19 HGQVDCNWLFLKSVPHFSAGAPRANVTSLSLISNRIHHLHDSDFVHLSNL---------- 68
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFC--TNLTELHLMSNSIQKIKNNPFVK 145
+VLNL+ N C L+ +H I+ N F+
Sbjct 69 --------------RVLNLKWN------------CPPAGLSPMHFPCR--MTIEPNTFLA 100
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQE----LLLSNNKIQALKSEELDIFANSSLKK 201
L L+LS+NG+++ + L+L L + ++ + +
Sbjct 101 VPTLEELNLSYNGITTVPALPSSLVSLSLSHTSILVLGPTHFTGLHALRF-LYMDGNCYY 159
Query 202 LELSSNQIKEFSPGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
+ + E +PG +G L L L NN+ P S+ L LS +
Sbjct 160 MNPCPRAL-EVAPGALLGLGNLTHLSLKYNNLTEVPRRLPP--------SLDTLLLSYNH 210
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYN----------------NLNVVGNDSFAWLPQLEYF 303
+ T + L T L +LD+ N N + D+F+ L +LE
Sbjct 211 IVTLAPEDLANL--TALRVLDVGGNCRRCDHARNPCRECPKNFPKLHPDTFSHLSRLEGL 268
Query 304 FLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNME 363
L+ +++ L GL ++ L+L +F I+ ++ F L L LN+
Sbjct 269 VLKDSSLYKLEKDWFRGLGRLQVLDLSENFLYDYITKTTI-------FNDLTQLRRLNLS 321
Query 364 DNDIPGIK------SNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILNLTK 416
N + ++ F L++L+ L + F R+LTN T SL P L L+L
Sbjct 322 FNYHKKVSFAHLHLASSFGSLVSLEKLDMHGIF--FRSLTNITLQSLTRLPKLQSLHLQL 379
Query 417 NKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI------------------ 458
N I++ + F L +DL N I
Sbjct 380 NFINQAQLSIFGAFPSLLFVDLSDNRISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 439
Query 459 -------------FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
F + LS N + + + F + LQ L L ++ + S F PL
Sbjct 440 XXXXXXXXSCNLNFTLDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSISQAVNG-SQFVPL 498
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
+L +LDLS+N + + L +LE LDL +N ++ + G + F+ L L
Sbjct 499 TSLRVLDLSHNKLDLYHGRSFTELPQLEALDLSYN--SQPFSMQGVGHNLSFVAQLPSLR 556
Query 566 ILNLESNGF-----------------------------DEIPVEVFKDLFELKIIDLGLN 596
L+L NG ++ + FK L L +DL N
Sbjct 557 YLSLAHNGIHSRVSQKLSSASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLDLSEN 616
Query 597 NLNT-LPASVFNNQVSLKSLNLQKN 620
+L+T LP + N SL+ L L+ N
Sbjct 617 HLHTLLPRHLDNLPKSLRQLRLRDN 641
Score = 36.2 bits (82), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 24/116 (21%)
Query 47 DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNL 106
D+LP ++ L L N L F +S LT LP L+ L+L
Sbjct 627 DNLPKSLRQLRLRDNNLA------FFNWSSLTV------------------LPRLEALDL 662
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSST 162
N+L LS+ + L +L + SNSI + FV+ LI L+LS N L +
Sbjct 663 AGNQLKALSNGSLPPGIRLQKLDVSSNSIGFVIPGFFVRATRLIELNLSANALKTV 718
>5z8y_G G Leucine-rich repeat transmembrane neuronal protein 2
Length=346
Score = 78.6 bits (192), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 87/305 (29%), Positives = 141/305 (46%), Gaps = 24/305 (8%)
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L LS + L + F S S L L+L N+IS ++ DAF L L+ L L N+I
Sbjct 31 LGLSLRHNHITELERDQFASF--SQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI 88
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
L + L N+ + LS+N+ L F + LQ L LR +L+ + F
Sbjct 89 FY-LPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTI--PVRLFW 145
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
R+L LDLS N + ++ + GL KL L L+HN L ++ +FL+ LS
Sbjct 146 DCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKI-------NFAHFLR-LSS 197
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
LH L L+ N + + L+ +DL N + + +VF +LK L + N +
Sbjct 198 LHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLN 257
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCT---CESIAWFVNWINETHTNIPELSSHYLCNTP 680
S++ K+ + R+LT + + N ++C+ C +W ++ +I LC++P
Sbjct 258 SLDSKILN-SLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSI-------LCHSP 309
Query 681 PHYHG 685
H G
Sbjct 310 DHTQG 314
Score = 72.8 bits (177), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 56/176 (32%), Positives = 87/176 (49%), Gaps = 2/176 (1%)
Query 58 LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDK 117
L+ N++ LP FT+ L +LD+ FN +S L PEL L L+ L+L+ N L + +
Sbjct 83 LSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVR 142
Query 118 TFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELL 177
F C +L L L +N ++ + N F L L L HN L+ ++L +L L
Sbjct 143 LFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLF 202
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
L NKI L + +L+KL+L+ N+IK F + L L ++N +L
Sbjct 203 LQWNKISNLTCGM--EWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKL 256
Score = 68.6 bits (166), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 89/331 (27%), Positives = 141/331 (43%), Gaps = 38/331 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC + C VP+ L+L HN + L F +SQLT
Sbjct 4 KCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLT-------- 55
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
L+L HN++S + + F L EL L SN I + N F +
Sbjct 56 ----------------WLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQL 99
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANS-SLKKLELS 205
NL LDLS N LSS L LQ L L +N +L++ + +F + SL+ L+LS
Sbjct 100 INLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN---SLRTIPVRLFWDCRSLEFLDLS 156
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
+N+++ + F + +L L L + QL L +S+ L L Q + SN
Sbjct 157 TNRLRSLARNGFAGLIKLRELHLEHNQLTKI---NFAHFLRLSSLHTLFL---QWNKISN 210
Query 266 TTFLGLKWT--NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
T G++WT L LDL+ N + + F +P L+ ++ N + L S L+ L +
Sbjct 211 LT-CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRS 269
Query 324 VRYLNLKRSFTKQSISLASLPK-IDDFSFQW 353
+ + L + + S + +L + F +W
Sbjct 270 LTTVGLSGNLWECSARICALASWLGSFQGRW 300
Score = 61.2 bits (147), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 67/262 (26%), Positives = 124/262 (47%), Gaps = 16/262 (6%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L +N++ + D FA QL + L++N I + + GL+ ++ L L S
Sbjct 33 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILS------SN 86
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+ LP +F L L++L++ N + + +F GL L+ L L ++ SLRT+
Sbjct 87 KIFYLPNT---TFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN--SLRTIPV 141
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
F L L+L+ N++ + + F+ L L L L N++ ++ + L ++
Sbjct 142 RLFWDC--RSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQL-TKINFAHFLRLSSL 198
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNI 518
++L +NK LT +L++L L +K +D + F+ + NL IL + NN +
Sbjct 199 HTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAID--LTVFETMPNLKILLMDNNKL 256
Query 519 ANINDDMLEGLEKLEILDLQHN 540
+++ +L L L + L N
Sbjct 257 NSLDSKILNSLRSLTTVGLSGN 278
>5z8y_E E Leucine-rich repeat transmembrane neuronal protein 2
Length=346
Score = 78.6 bits (192), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 87/305 (29%), Positives = 141/305 (46%), Gaps = 24/305 (8%)
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L LS + L + F S S L L+L N+IS ++ DAF L L+ L L N+I
Sbjct 31 LGLSLRHNHITELERDQFASF--SQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI 88
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
L + L N+ + LS+N+ L F + LQ L LR +L+ + F
Sbjct 89 FY-LPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTI--PVRLFW 145
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
R+L LDLS N + ++ + GL KL L L+HN L ++ +FL+ LS
Sbjct 146 DCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKI-------NFAHFLR-LSS 197
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
LH L L+ N + + L+ +DL N + + +VF +LK L + N +
Sbjct 198 LHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLN 257
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCT---CESIAWFVNWINETHTNIPELSSHYLCNTP 680
S++ K+ + R+LT + + N ++C+ C +W ++ +I LC++P
Sbjct 258 SLDSKILN-SLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSI-------LCHSP 309
Query 681 PHYHG 685
H G
Sbjct 310 DHTQG 314
Score = 72.8 bits (177), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 56/176 (32%), Positives = 87/176 (49%), Gaps = 2/176 (1%)
Query 58 LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDK 117
L+ N++ LP FT+ L +LD+ FN +S L PEL L L+ L+L+ N L + +
Sbjct 83 LSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVR 142
Query 118 TFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELL 177
F C +L L L +N ++ + N F L L L HN L+ ++L +L L
Sbjct 143 LFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLF 202
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
L NKI L + +L+KL+L+ N+IK F + L L ++N +L
Sbjct 203 LQWNKISNLTCGM--EWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKL 256
Score = 68.6 bits (166), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 89/331 (27%), Positives = 141/331 (43%), Gaps = 38/331 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC + C VP+ L+L HN + L F +SQLT
Sbjct 4 KCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLT-------- 55
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
L+L HN++S + + F L EL L SN I + N F +
Sbjct 56 ----------------WLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQL 99
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANS-SLKKLELS 205
NL LDLS N LSS L LQ L L +N +L++ + +F + SL+ L+LS
Sbjct 100 INLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN---SLRTIPVRLFWDCRSLEFLDLS 156
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
+N+++ + F + +L L L + QL L +S+ L L Q + SN
Sbjct 157 TNRLRSLARNGFAGLIKLRELHLEHNQLTKI---NFAHFLRLSSLHTLFL---QWNKISN 210
Query 266 TTFLGLKWT--NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
T G++WT L LDL+ N + + F +P L+ ++ N + L S L+ L +
Sbjct 211 LT-CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRS 269
Query 324 VRYLNLKRSFTKQSISLASLPK-IDDFSFQW 353
+ + L + + S + +L + F +W
Sbjct 270 LTTVGLSGNLWECSARICALASWLGSFQGRW 300
Score = 61.2 bits (147), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 67/262 (26%), Positives = 124/262 (47%), Gaps = 16/262 (6%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L +N++ + D FA QL + L++N I + + GL+ ++ L L S
Sbjct 33 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILS------SN 86
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+ LP +F L L++L++ N + + +F GL L+ L L ++ SLRT+
Sbjct 87 KIFYLPNT---TFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN--SLRTIPV 141
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
F L L+L+ N++ + + F+ L L L L N++ ++ + L ++
Sbjct 142 RLFWDC--RSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQL-TKINFAHFLRLSSL 198
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNI 518
++L +NK LT +L++L L +K +D + F+ + NL IL + NN +
Sbjct 199 HTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAID--LTVFETMPNLKILLMDNNKL 256
Query 519 ANINDDMLEGLEKLEILDLQHN 540
+++ +L L L + L N
Sbjct 257 NSLDSKILNSLRSLTTVGLSGN 278
>5z8y_A A Leucine-rich repeat transmembrane neuronal protein 2
Length=346
Score = 78.6 bits (192), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 87/305 (29%), Positives = 141/305 (46%), Gaps = 24/305 (8%)
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L LS + L + F S S L L+L N+IS ++ DAF L L+ L L N+I
Sbjct 31 LGLSLRHNHITELERDQFASF--SQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI 88
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
L + L N+ + LS+N+ L F + LQ L LR +L+ + F
Sbjct 89 FY-LPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTI--PVRLFW 145
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
R+L LDLS N + ++ + GL KL L L+HN L ++ +FL+ LS
Sbjct 146 DCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKI-------NFAHFLR-LSS 197
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
LH L L+ N + + L+ +DL N + + +VF +LK L + N +
Sbjct 198 LHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLN 257
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCT---CESIAWFVNWINETHTNIPELSSHYLCNTP 680
S++ K+ + R+LT + + N ++C+ C +W ++ +I LC++P
Sbjct 258 SLDSKILN-SLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSI-------LCHSP 309
Query 681 PHYHG 685
H G
Sbjct 310 DHTQG 314
Score = 72.8 bits (177), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 56/176 (32%), Positives = 87/176 (49%), Gaps = 2/176 (1%)
Query 58 LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDK 117
L+ N++ LP FT+ L +LD+ FN +S L PEL L L+ L+L+ N L + +
Sbjct 83 LSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVR 142
Query 118 TFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELL 177
F C +L L L +N ++ + N F L L L HN L+ ++L +L L
Sbjct 143 LFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLF 202
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
L NKI L + +L+KL+L+ N+IK F + L L ++N +L
Sbjct 203 LQWNKISNLTCGM--EWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKL 256
Score = 68.6 bits (166), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 89/331 (27%), Positives = 141/331 (43%), Gaps = 38/331 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC + C VP+ L+L HN + L F +SQLT
Sbjct 4 KCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLT-------- 55
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
L+L HN++S + + F L EL L SN I + N F +
Sbjct 56 ----------------WLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQL 99
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANS-SLKKLELS 205
NL LDLS N LSS L LQ L L +N +L++ + +F + SL+ L+LS
Sbjct 100 INLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN---SLRTIPVRLFWDCRSLEFLDLS 156
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
+N+++ + F + +L L L + QL L +S+ L L Q + SN
Sbjct 157 TNRLRSLARNGFAGLIKLRELHLEHNQLTKI---NFAHFLRLSSLHTLFL---QWNKISN 210
Query 266 TTFLGLKWT--NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
T G++WT L LDL+ N + + F +P L+ ++ N + L S L+ L +
Sbjct 211 LT-CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRS 269
Query 324 VRYLNLKRSFTKQSISLASLPK-IDDFSFQW 353
+ + L + + S + +L + F +W
Sbjct 270 LTTVGLSGNLWECSARICALASWLGSFQGRW 300
Score = 61.2 bits (147), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 67/262 (26%), Positives = 124/262 (47%), Gaps = 16/262 (6%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L +N++ + D FA QL + L++N I + + GL+ ++ L L S
Sbjct 33 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILS------SN 86
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+ LP +F L L++L++ N + + +F GL L+ L L ++ SLRT+
Sbjct 87 KIFYLPNT---TFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN--SLRTIPV 141
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
F L L+L+ N++ + + F+ L L L L N++ ++ + L ++
Sbjct 142 RLFWDC--RSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQL-TKINFAHFLRLSSL 198
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNI 518
++L +NK LT +L++L L +K +D + F+ + NL IL + NN +
Sbjct 199 HTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAID--LTVFETMPNLKILLMDNNKL 256
Query 519 ANINDDMLEGLEKLEILDLQHN 540
+++ +L L L + L N
Sbjct 257 NSLDSKILNSLRSLTTVGLSGN 278
>5z8y_C C Leucine-rich repeat transmembrane neuronal protein 2
Length=346
Score = 78.6 bits (192), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 87/305 (29%), Positives = 141/305 (46%), Gaps = 24/305 (8%)
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L LS + L + F S S L L+L N+IS ++ DAF L L+ L L N+I
Sbjct 31 LGLSLRHNHITELERDQFASF--SQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI 88
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
L + L N+ + LS+N+ L F + LQ L LR +L+ + F
Sbjct 89 FY-LPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTI--PVRLFW 145
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
R+L LDLS N + ++ + GL KL L L+HN L ++ +FL+ LS
Sbjct 146 DCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKI-------NFAHFLR-LSS 197
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
LH L L+ N + + L+ +DL N + + +VF +LK L + N +
Sbjct 198 LHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLN 257
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCT---CESIAWFVNWINETHTNIPELSSHYLCNTP 680
S++ K+ + R+LT + + N ++C+ C +W ++ +I LC++P
Sbjct 258 SLDSKILN-SLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSI-------LCHSP 309
Query 681 PHYHG 685
H G
Sbjct 310 DHTQG 314
Score = 72.8 bits (177), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 56/176 (32%), Positives = 87/176 (49%), Gaps = 2/176 (1%)
Query 58 LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDK 117
L+ N++ LP FT+ L +LD+ FN +S L PEL L L+ L+L+ N L + +
Sbjct 83 LSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVR 142
Query 118 TFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELL 177
F C +L L L +N ++ + N F L L L HN L+ ++L +L L
Sbjct 143 LFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLF 202
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
L NKI L + +L+KL+L+ N+IK F + L L ++N +L
Sbjct 203 LQWNKISNLTCGM--EWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKL 256
Score = 68.6 bits (166), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 89/331 (27%), Positives = 141/331 (43%), Gaps = 38/331 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC + C VP+ L+L HN + L F +SQLT
Sbjct 4 KCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLT-------- 55
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
L+L HN++S + + F L EL L SN I + N F +
Sbjct 56 ----------------WLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQL 99
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANS-SLKKLELS 205
NL LDLS N LSS L LQ L L +N +L++ + +F + SL+ L+LS
Sbjct 100 INLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN---SLRTIPVRLFWDCRSLEFLDLS 156
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
+N+++ + F + +L L L + QL L +S+ L L Q + SN
Sbjct 157 TNRLRSLARNGFAGLIKLRELHLEHNQLTKI---NFAHFLRLSSLHTLFL---QWNKISN 210
Query 266 TTFLGLKWT--NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
T G++WT L LDL+ N + + F +P L+ ++ N + L S L+ L +
Sbjct 211 LT-CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRS 269
Query 324 VRYLNLKRSFTKQSISLASLPK-IDDFSFQW 353
+ + L + + S + +L + F +W
Sbjct 270 LTTVGLSGNLWECSARICALASWLGSFQGRW 300
Score = 61.2 bits (147), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 67/262 (26%), Positives = 124/262 (47%), Gaps = 16/262 (6%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L +N++ + D FA QL + L++N I + + GL+ ++ L L S
Sbjct 33 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILS------SN 86
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+ LP +F L L++L++ N + + +F GL L+ L L ++ SLRT+
Sbjct 87 KIFYLPNT---TFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN--SLRTIPV 141
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
F L L+L+ N++ + + F+ L L L L N++ ++ + L ++
Sbjct 142 RLFWDC--RSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQL-TKINFAHFLRLSSL 198
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNI 518
++L +NK LT +L++L L +K +D + F+ + NL IL + NN +
Sbjct 199 HTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAID--LTVFETMPNLKILLMDNNKL 256
Query 519 ANINDDMLEGLEKLEILDLQHN 540
+++ +L L L + L N
Sbjct 257 NSLDSKILNSLRSLTTVGLSGN 278
>5z8x_C C Leucine-rich repeat transmembrane neuronal protein 2
Length=346
Score = 78.6 bits (192), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 87/305 (29%), Positives = 141/305 (46%), Gaps = 24/305 (8%)
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L LS + L + F S S L L+L N+IS ++ DAF L L+ L L N+I
Sbjct 31 LGLSLRHNHITELERDQFASF--SQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI 88
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
L + L N+ + LS+N+ L F + LQ L LR +L+ + F
Sbjct 89 FY-LPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTI--PVRLFW 145
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
R+L LDLS N + ++ + GL KL L L+HN L ++ +FL+ LS
Sbjct 146 DCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKI-------NFAHFLR-LSS 197
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
LH L L+ N + + L+ +DL N + + +VF +LK L + N +
Sbjct 198 LHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLN 257
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCT---CESIAWFVNWINETHTNIPELSSHYLCNTP 680
S++ K+ + R+LT + + N ++C+ C +W ++ +I LC++P
Sbjct 258 SLDSKILN-SLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSI-------LCHSP 309
Query 681 PHYHG 685
H G
Sbjct 310 DHTQG 314
Score = 72.8 bits (177), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 56/176 (32%), Positives = 87/176 (49%), Gaps = 2/176 (1%)
Query 58 LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDK 117
L+ N++ LP FT+ L +LD+ FN +S L PEL L L+ L+L+ N L + +
Sbjct 83 LSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVR 142
Query 118 TFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELL 177
F C +L L L +N ++ + N F L L L HN L+ ++L +L L
Sbjct 143 LFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLF 202
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
L NKI L + +L+KL+L+ N+IK F + L L ++N +L
Sbjct 203 LQWNKISNLTCGM--EWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKL 256
Score = 70.5 bits (171), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 90/331 (27%), Positives = 142/331 (43%), Gaps = 38/331 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC + C VP+ L L+L HN + L F +SQLT
Sbjct 4 KCRCEKLLFYCDSQGFHSVPNALDKGSLGLSLRHNHITELERDQFASFSQLT-------- 55
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
L+L HN++S + + F L EL L SN I + N F +
Sbjct 56 ----------------WLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQL 99
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANS-SLKKLELS 205
NL LDLS N LSS L LQ L L +N +L++ + +F + SL+ L+LS
Sbjct 100 INLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN---SLRTIPVRLFWDCRSLEFLDLS 156
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
+N+++ + F + +L L L + QL L +S+ L L Q + SN
Sbjct 157 TNRLRSLARNGFAGLIKLRELHLEHNQLTKI---NFAHFLRLSSLHTLFL---QWNKISN 210
Query 266 TTFLGLKWT--NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
T G++WT L LDL+ N + + F +P L+ ++ N + L S L+ L +
Sbjct 211 LT-CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRS 269
Query 324 VRYLNLKRSFTKQSISLASLPK-IDDFSFQW 353
+ + L + + S + +L + F +W
Sbjct 270 LTTVGLSGNLWECSARICALASWLGSFQGRW 300
Score = 61.2 bits (147), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 67/262 (26%), Positives = 124/262 (47%), Gaps = 16/262 (6%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L +N++ + D FA QL + L++N I + + GL+ ++ L L S
Sbjct 33 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILS------SN 86
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+ LP +F L L++L++ N + + +F GL L+ L L ++ SLRT+
Sbjct 87 KIFYLPNT---TFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN--SLRTIPV 141
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
F L L+L+ N++ + + F+ L L L L N++ ++ + L ++
Sbjct 142 RLFWDC--RSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQL-TKINFAHFLRLSSL 198
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNI 518
++L +NK LT +L++L L +K +D + F+ + NL IL + NN +
Sbjct 199 HTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAID--LTVFETMPNLKILLMDNNKL 256
Query 519 ANINDDMLEGLEKLEILDLQHN 540
+++ +L L L + L N
Sbjct 257 NSLDSKILNSLRSLTTVGLSGN 278
>5z8x_A A Leucine-rich repeat transmembrane neuronal protein 2
Length=346
Score = 78.6 bits (192), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 87/305 (29%), Positives = 141/305 (46%), Gaps = 24/305 (8%)
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L LS + L + F S S L L+L N+IS ++ DAF L L+ L L N+I
Sbjct 31 LGLSLRHNHITELERDQFASF--SQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI 88
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
L + L N+ + LS+N+ L F + LQ L LR +L+ + F
Sbjct 89 FY-LPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTI--PVRLFW 145
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
R+L LDLS N + ++ + GL KL L L+HN L ++ +FL+ LS
Sbjct 146 DCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKI-------NFAHFLR-LSS 197
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
LH L L+ N + + L+ +DL N + + +VF +LK L + N +
Sbjct 198 LHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLN 257
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCT---CESIAWFVNWINETHTNIPELSSHYLCNTP 680
S++ K+ + R+LT + + N ++C+ C +W ++ +I LC++P
Sbjct 258 SLDSKILN-SLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSI-------LCHSP 309
Query 681 PHYHG 685
H G
Sbjct 310 DHTQG 314
Score = 72.8 bits (177), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 56/176 (32%), Positives = 87/176 (49%), Gaps = 2/176 (1%)
Query 58 LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDK 117
L+ N++ LP FT+ L +LD+ FN +S L PEL L L+ L+L+ N L + +
Sbjct 83 LSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVR 142
Query 118 TFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELL 177
F C +L L L +N ++ + N F L L L HN L+ ++L +L L
Sbjct 143 LFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLF 202
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
L NKI L + +L+KL+L+ N+IK F + L L ++N +L
Sbjct 203 LQWNKISNLTCGM--EWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKL 256
Score = 70.5 bits (171), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 90/331 (27%), Positives = 142/331 (43%), Gaps = 38/331 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC + C VP+ L L+L HN + L F +SQLT
Sbjct 4 KCRCEKLLFYCDSQGFHSVPNALDKGSLGLSLRHNHITELERDQFASFSQLT-------- 55
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
L+L HN++S + + F L EL L SN I + N F +
Sbjct 56 ----------------WLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQL 99
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANS-SLKKLELS 205
NL LDLS N LSS L LQ L L +N +L++ + +F + SL+ L+LS
Sbjct 100 INLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN---SLRTIPVRLFWDCRSLEFLDLS 156
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
+N+++ + F + +L L L + QL L +S+ L L Q + SN
Sbjct 157 TNRLRSLARNGFAGLIKLRELHLEHNQLTKI---NFAHFLRLSSLHTLFL---QWNKISN 210
Query 266 TTFLGLKWT--NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
T G++WT L LDL+ N + + F +P L+ ++ N + L S L+ L +
Sbjct 211 LT-CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRS 269
Query 324 VRYLNLKRSFTKQSISLASLPK-IDDFSFQW 353
+ + L + + S + +L + F +W
Sbjct 270 LTTVGLSGNLWECSARICALASWLGSFQGRW 300
Score = 61.2 bits (147), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 67/262 (26%), Positives = 124/262 (47%), Gaps = 16/262 (6%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L +N++ + D FA QL + L++N I + + GL+ ++ L L S
Sbjct 33 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILS------SN 86
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+ LP +F L L++L++ N + + +F GL L+ L L ++ SLRT+
Sbjct 87 KIFYLPNT---TFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN--SLRTIPV 141
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
F L L+L+ N++ + + F+ L L L L N++ ++ + L ++
Sbjct 142 RLFWDC--RSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQL-TKINFAHFLRLSSL 198
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNI 518
++L +NK LT +L++L L +K +D + F+ + NL IL + NN +
Sbjct 199 HTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAID--LTVFETMPNLKILLMDNNKL 256
Query 519 ANINDDMLEGLEKLEILDLQHN 540
+++ +L L L + L N
Sbjct 257 NSLDSKILNSLRSLTTVGLSGN 278
>5z8x_D D Leucine-rich repeat transmembrane neuronal protein 2
Length=346
Score = 78.6 bits (192), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 87/305 (29%), Positives = 141/305 (46%), Gaps = 24/305 (8%)
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L LS + L + F S S L L+L N+IS ++ DAF L L+ L L N+I
Sbjct 31 LGLSLRHNHITELERDQFASF--SQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI 88
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
L + L N+ + LS+N+ L F + LQ L LR +L+ + F
Sbjct 89 FY-LPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTI--PVRLFW 145
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
R+L LDLS N + ++ + GL KL L L+HN L ++ +FL+ LS
Sbjct 146 DCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKI-------NFAHFLR-LSS 197
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
LH L L+ N + + L+ +DL N + + +VF +LK L + N +
Sbjct 198 LHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLN 257
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCT---CESIAWFVNWINETHTNIPELSSHYLCNTP 680
S++ K+ + R+LT + + N ++C+ C +W ++ +I LC++P
Sbjct 258 SLDSKILN-SLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSI-------LCHSP 309
Query 681 PHYHG 685
H G
Sbjct 310 DHTQG 314
Score = 72.8 bits (177), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 56/176 (32%), Positives = 87/176 (49%), Gaps = 2/176 (1%)
Query 58 LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDK 117
L+ N++ LP FT+ L +LD+ FN +S L PEL L L+ L+L+ N L + +
Sbjct 83 LSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVR 142
Query 118 TFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELL 177
F C +L L L +N ++ + N F L L L HN L+ ++L +L L
Sbjct 143 LFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLF 202
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
L NKI L + +L+KL+L+ N+IK F + L L ++N +L
Sbjct 203 LQWNKISNLTCGM--EWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKL 256
Score = 70.5 bits (171), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 90/331 (27%), Positives = 142/331 (43%), Gaps = 38/331 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC + C VP+ L L+L HN + L F +SQLT
Sbjct 4 KCRCEKLLFYCDSQGFHSVPNALDKGSLGLSLRHNHITELERDQFASFSQLT-------- 55
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
L+L HN++S + + F L EL L SN I + N F +
Sbjct 56 ----------------WLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQL 99
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANS-SLKKLELS 205
NL LDLS N LSS L LQ L L +N +L++ + +F + SL+ L+LS
Sbjct 100 INLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN---SLRTIPVRLFWDCRSLEFLDLS 156
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
+N+++ + F + +L L L + QL L +S+ L L Q + SN
Sbjct 157 TNRLRSLARNGFAGLIKLRELHLEHNQLTKI---NFAHFLRLSSLHTLFL---QWNKISN 210
Query 266 TTFLGLKWT--NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
T G++WT L LDL+ N + + F +P L+ ++ N + L S L+ L +
Sbjct 211 LT-CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRS 269
Query 324 VRYLNLKRSFTKQSISLASLPK-IDDFSFQW 353
+ + L + + S + +L + F +W
Sbjct 270 LTTVGLSGNLWECSARICALASWLGSFQGRW 300
Score = 61.2 bits (147), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 67/262 (26%), Positives = 124/262 (47%), Gaps = 16/262 (6%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L +N++ + D FA QL + L++N I + + GL+ ++ L L S
Sbjct 33 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILS------SN 86
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+ LP +F L L++L++ N + + +F GL L+ L L ++ SLRT+
Sbjct 87 KIFYLPNT---TFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN--SLRTIPV 141
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
F L L+L+ N++ + + F+ L L L L N++ ++ + L ++
Sbjct 142 RLFWDC--RSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQL-TKINFAHFLRLSSL 198
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNI 518
++L +NK LT +L++L L +K +D + F+ + NL IL + NN +
Sbjct 199 HTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAID--LTVFETMPNLKILLMDNNKL 256
Query 519 ANINDDMLEGLEKLEILDLQHN 540
+++ +L L L + L N
Sbjct 257 NSLDSKILNSLRSLTTVGLSGN 278
>5z8x_B B Leucine-rich repeat transmembrane neuronal protein 2
Length=346
Score = 78.6 bits (192), Expect = 4e-14, Method: Compositional matrix adjust.
Identities = 87/305 (29%), Positives = 141/305 (46%), Gaps = 24/305 (8%)
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L LS + L + F S S L L+L N+IS ++ DAF L L+ L L N+I
Sbjct 31 LGLSLRHNHITELERDQFASF--SQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKI 88
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
L + L N+ + LS+N+ L F + LQ L LR +L+ + F
Sbjct 89 FY-LPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTI--PVRLFW 145
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
R+L LDLS N + ++ + GL KL L L+HN L ++ +FL+ LS
Sbjct 146 DCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKI-------NFAHFLR-LSS 197
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
LH L L+ N + + L+ +DL N + + +VF +LK L + N +
Sbjct 198 LHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLN 257
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCT---CESIAWFVNWINETHTNIPELSSHYLCNTP 680
S++ K+ + R+LT + + N ++C+ C +W ++ +I LC++P
Sbjct 258 SLDSKILN-SLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSI-------LCHSP 309
Query 681 PHYHG 685
H G
Sbjct 310 DHTQG 314
Score = 72.8 bits (177), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 56/176 (32%), Positives = 87/176 (49%), Gaps = 2/176 (1%)
Query 58 LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDK 117
L+ N++ LP FT+ L +LD+ FN +S L PEL L L+ L+L+ N L + +
Sbjct 83 LSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVR 142
Query 118 TFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELL 177
F C +L L L +N ++ + N F L L L HN L+ ++L +L L
Sbjct 143 LFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLF 202
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
L NKI L + +L+KL+L+ N+IK F + L L ++N +L
Sbjct 203 LQWNKISNLTCGM--EWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKL 256
Score = 70.5 bits (171), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 90/331 (27%), Positives = 142/331 (43%), Gaps = 38/331 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC + C VP+ L L+L HN + L F +SQLT
Sbjct 4 KCRCEKLLFYCDSQGFHSVPNALDKGSLGLSLRHNHITELERDQFASFSQLT-------- 55
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
L+L HN++S + + F L EL L SN I + N F +
Sbjct 56 ----------------WLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQL 99
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANS-SLKKLELS 205
NL LDLS N LSS L LQ L L +N +L++ + +F + SL+ L+LS
Sbjct 100 INLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN---SLRTIPVRLFWDCRSLEFLDLS 156
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
+N+++ + F + +L L L + QL L +S+ L L Q + SN
Sbjct 157 TNRLRSLARNGFAGLIKLRELHLEHNQLTKI---NFAHFLRLSSLHTLFL---QWNKISN 210
Query 266 TTFLGLKWT--NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
T G++WT L LDL+ N + + F +P L+ ++ N + L S L+ L +
Sbjct 211 LT-CGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRS 269
Query 324 VRYLNLKRSFTKQSISLASLPK-IDDFSFQW 353
+ + L + + S + +L + F +W
Sbjct 270 LTTVGLSGNLWECSARICALASWLGSFQGRW 300
Score = 61.2 bits (147), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 67/262 (26%), Positives = 124/262 (47%), Gaps = 16/262 (6%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L +N++ + D FA QL + L++N I + + GL+ ++ L L S
Sbjct 33 LSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILS------SN 86
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
+ LP +F L L++L++ N + + +F GL L+ L L ++ SLRT+
Sbjct 87 KIFYLPNT---TFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSN--SLRTIPV 141
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI 458
F L L+L+ N++ + + F+ L L L L N++ ++ + L ++
Sbjct 142 RLFWDC--RSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQL-TKINFAHFLRLSSL 198
Query 459 FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNI 518
++L +NK LT +L++L L +K +D + F+ + NL IL + NN +
Sbjct 199 HTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAID--LTVFETMPNLKILLMDNNKL 256
Query 519 ANINDDMLEGLEKLEILDLQHN 540
+++ +L L L + L N
Sbjct 257 NSLDSKILNSLRSLTTVGLSGN 278
>3wo9_A A Variable lymphocyte receptor C
Length=248
Score = 75.5 bits (184), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 60/157 (38%), Positives = 75/157 (48%), Gaps = 1/157 (1%)
Query 20 LCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTS 79
+C S K S E DCS KLT VP +P N L L NQL +PA F ++LT
Sbjct 36 ICTCSN-KTDSSPETVDCSSKKLTAVPTGIPANTEKLQLDFNQLANIPAEAFHGLTRLTY 94
Query 80 LDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
L + +N + L + +L L L LQ N+L+ L F T LT L L N +Q I
Sbjct 95 LALDYNQLQSLPVGVFDQLNNLNELRLQDNQLTSLPPGVFDSLTKLTYLTLSQNQLQSIP 154
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQEL 176
F K NL L+LS N L S G L NL+ L
Sbjct 155 AGVFDKLTNLNRLELSTNQLQSVPHGAFDSLVNLETL 191
Score = 72.4 bits (176), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 53/168 (32%), Positives = 77/168 (46%), Gaps = 10/168 (6%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
L L N +ANI + GL +L L L +N L L P+ L++L+ L L+
Sbjct 71 LQLDFNQLANIPAEAFHGLTRLTYLALDYNQLQSL--------PVGVFDQLNNLNELRLQ 122
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N +P VF L +L + L N L ++PA VF+ +L L L N + SV F
Sbjct 123 DNQLTSLPPGVFDSLTKLTYLTLSQNQLQSIPAGVFDKLTNLNRLELSTNQLQSVPHGAF 182
Query 631 GPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCN 678
+ NL L + NP+DC C I + +I + I + S CN
Sbjct 183 D-SLVNLETLHLELNPWDCACSDIIYLRTFIAKNTDKISGMESAQ-CN 228
Score = 47.8 bits (112), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 42/141 (30%), Positives = 68/141 (48%), Gaps = 13/141 (9%)
Query 301 EYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHL 360
E L++N + ++ + + HGL + YL L + L SLP F L L L
Sbjct 69 EKLQLDFNQLANIPAEAFHGLTRLTYLALDYN------QLQSLPV---GVFDQLNNLNEL 119
Query 361 NMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
++DN + + +F L L YL+LS + L+++ F L + L+ L L+ N++
Sbjct 120 RLQDNQLTSLPPGVFDSLTKLTYLTLSQN--QLQSIPAGVFDKLTN--LNRLELSTNQLQ 175
Query 421 KIESDAFSWLGHLEVLDLGLN 441
+ AF L +LE L L LN
Sbjct 176 SVPHGAFDSLVNLETLHLELN 196
Score = 36.2 bits (82), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 52/189 (28%), Positives = 73/189 (39%), Gaps = 33/189 (17%)
Query 122 CTNLTEL--HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLS 179
C+N T+ + S +K+ P N L L N L++ L L L L
Sbjct 39 CSNKTDSSPETVDCSSKKLTAVPTGIPANTEKLQLDFNQLANIPAEAFHGLTRLTYLALD 98
Query 180 NNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTE 239
N++Q+L D N L +L L NQ+ PG F ++
Sbjct 99 YNQLQSLPVGVFDQLNN--LNELRLQDNQLTSLPPGVFDSL------------------- 137
Query 240 KLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQ 299
T + L+LS +QL + F K TNL L+LS N L V + +F L
Sbjct 138 --------TKLTYLTLSQNQLQSIPAGVF--DKLTNLNRLELSTNQLQSVPHGAFDSLVN 187
Query 300 LEYFFLEYN 308
LE LE N
Sbjct 188 LETLHLELN 196
>2o6s_B B Variable lymphocyte receptor B
Length=208
Score = 74.3 bits (181), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 10/160 (6%)
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
T LDL N++ ++ + + + L L L L N L L P L+ L LN
Sbjct 31 TYLDLETNSLKSLPNGVFDELTSLTQLYLGGNKLQSL--------PNGVFNKLTSLTYLN 82
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
L +N +P VF L +LK + L N L +LP VF+ LK L L +N + SV
Sbjct 83 LSTNQLQSLPNGVFDKLTQLKELALNTNQLQSLPDGVFDKLTQLKDLRLYQNQLKSVPDG 142
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
VF +L + + NP+DCTC I + WIN+ H+ +
Sbjct 143 VFD-RLTSLQYIWLHDNPWDCTCPGIRYLSEWINK-HSGV 180
Score = 72.0 bits (175), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 52/156 (33%), Positives = 73/156 (47%), Gaps = 0/156 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S +C T VP +P T L+L N L+ LP F + LT L +G N
Sbjct 3 SRCSCSGTTVECYSQGRTSVPTGIPAQTTYLDLETNSLKSLPNGVFDELTSLTQLYLGGN 62
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ L + KL L LNL N+L L + F T L EL L +N +Q + + F K
Sbjct 63 KLQSLPNGVFNKLTSLTYLNLSTNQLQSLPNGVFDKLTQLKELALNTNQLQSLPDGVFDK 122
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
L L L N L S G +L +LQ + L +N
Sbjct 123 LTQLKDLRLYQNQLKSVPDGVFDRLTSLQYIWLHDN 158
Score = 58.5 bits (140), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 44/127 (35%), Positives = 67/127 (53%), Gaps = 2/127 (2%)
Query 104 LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTK 163
L+L+ N L L + F T+LT+L+L N +Q + N F K +L L+LS N L S
Sbjct 33 LDLETNSLKSLPNGVFDELTSLTQLYLGGNKLQSLPNGVFNKLTSLTYLNLSTNQLQSLP 92
Query 164 LGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
G +L L+EL L+ N++Q+L D + LK L L NQ+K G F + L
Sbjct 93 NGVFDKLTQLKELALNTNQLQSLPDGVFDKL--TQLKDLRLYQNQLKSVPDGVFDRLTSL 150
Query 224 FGLFLNN 230
++L++
Sbjct 151 QYIWLHD 157
Score = 40.4 bits (93), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 39/117 (33%), Positives = 61/117 (52%), Gaps = 5/117 (4%)
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
LDL N L S G +L +L +L L NK+Q+L + + +SL L LS+NQ++
Sbjct 33 LDLETNSLKSLPNGVFDELTSLTQLYLGGNKLQSLPNGVFNKL--TSLTYLNLSTNQLQS 90
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
G F + +L L LN QL SL + + +L T +++L L +QL + + F
Sbjct 91 LPNGVFDKLTQLKELALNTNQLQ-SLPDGVFDKL--TQLKDLRLYQNQLKSVPDGVF 144
Score = 34.7 bits (78), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 36/110 (33%), Positives = 50/110 (45%), Gaps = 9/110 (8%)
Query 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQ 336
T LDL N+L + N F L L +L N +Q L + + L ++ YLNL T Q
Sbjct 31 TYLDLETNSLKSLPNGVFDELTSLTQLYLGGNKLQSLPNGVFNKLTSLTYLNLS---TNQ 87
Query 337 SISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
L SLP + F L L+ L + N + + +F L LK L L
Sbjct 88 ---LQSLP---NGVFDKLTQLKELALNTNQLQSLPDGVFDKLTQLKDLRL 131
>2o6s_A A Variable lymphocyte receptor B
Length=208
Score = 74.3 bits (181), Expect = 1e-13, Method: Compositional matrix adjust.
Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 10/160 (6%)
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
T LDL N++ ++ + + + L L L L N L L P L+ L LN
Sbjct 31 TYLDLETNSLKSLPNGVFDELTSLTQLYLGGNKLQSL--------PNGVFNKLTSLTYLN 82
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
L +N +P VF L +LK + L N L +LP VF+ LK L L +N + SV
Sbjct 83 LSTNQLQSLPNGVFDKLTQLKELALNTNQLQSLPDGVFDKLTQLKDLRLYQNQLKSVPDG 142
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
VF +L + + NP+DCTC I + WIN+ H+ +
Sbjct 143 VFD-RLTSLQYIWLHDNPWDCTCPGIRYLSEWINK-HSGV 180
Score = 72.0 bits (175), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 52/156 (33%), Positives = 73/156 (47%), Gaps = 0/156 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S +C T VP +P T L+L N L+ LP F + LT L +G N
Sbjct 3 SRCSCSGTTVECYSQGRTSVPTGIPAQTTYLDLETNSLKSLPNGVFDELTSLTQLYLGGN 62
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ L + KL L LNL N+L L + F T L EL L +N +Q + + F K
Sbjct 63 KLQSLPNGVFNKLTSLTYLNLSTNQLQSLPNGVFDKLTQLKELALNTNQLQSLPDGVFDK 122
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
L L L N L S G +L +LQ + L +N
Sbjct 123 LTQLKDLRLYQNQLKSVPDGVFDRLTSLQYIWLHDN 158
Score = 58.5 bits (140), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 44/127 (35%), Positives = 67/127 (53%), Gaps = 2/127 (2%)
Query 104 LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTK 163
L+L+ N L L + F T+LT+L+L N +Q + N F K +L L+LS N L S
Sbjct 33 LDLETNSLKSLPNGVFDELTSLTQLYLGGNKLQSLPNGVFNKLTSLTYLNLSTNQLQSLP 92
Query 164 LGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
G +L L+EL L+ N++Q+L D + LK L L NQ+K G F + L
Sbjct 93 NGVFDKLTQLKELALNTNQLQSLPDGVFDKL--TQLKDLRLYQNQLKSVPDGVFDRLTSL 150
Query 224 FGLFLNN 230
++L++
Sbjct 151 QYIWLHD 157
Score = 40.4 bits (93), Expect = 0.042, Method: Compositional matrix adjust.
Identities = 39/117 (33%), Positives = 61/117 (52%), Gaps = 5/117 (4%)
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
LDL N L S G +L +L +L L NK+Q+L + + +SL L LS+NQ++
Sbjct 33 LDLETNSLKSLPNGVFDELTSLTQLYLGGNKLQSLPNGVFNKL--TSLTYLNLSTNQLQS 90
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
G F + +L L LN QL SL + + +L T +++L L +QL + + F
Sbjct 91 LPNGVFDKLTQLKELALNTNQLQ-SLPDGVFDKL--TQLKDLRLYQNQLKSVPDGVF 144
Score = 34.7 bits (78), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 36/110 (33%), Positives = 50/110 (45%), Gaps = 9/110 (8%)
Query 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQ 336
T LDL N+L + N F L L +L N +Q L + + L ++ YLNL T Q
Sbjct 31 TYLDLETNSLKSLPNGVFDELTSLTQLYLGGNKLQSLPNGVFNKLTSLTYLNLS---TNQ 87
Query 337 SISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
L SLP + F L L+ L + N + + +F L LK L L
Sbjct 88 ---LQSLP---NGVFDKLTQLKELALNTNQLQSLPDGVFDKLTQLKDLRL 131
>3rfs_A A Internalin B, repeat modules, Variable lymphocyte receptor
B
Length=272
Score = 75.5 bits (184), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 65/213 (31%), Positives = 99/213 (46%), Gaps = 16/213 (8%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L L L ++ S + L NLT L L+ N + ++ + + + L L+ L L
Sbjct 62 LPNVRYLALGGNKLHDI----SALKELTNLTYLILTGNQLQSLPNGVFDKLTNLKELVLV 117
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P L++L LNL N +P VF L L +DL N L
Sbjct 118 ENQLQSL--------PDGVFDKLTNLTYLNLAHNQLQSLPKGVFDKLTNLTELDLSYNQL 169
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L L +N + SV VF +L + + NP+DCTC I +
Sbjct 170 QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRYLS 228
Query 659 NWINETHTNIPELSSHYLC--NTPPHYHGFPVR 689
WIN+ H+ + S+ + + G PVR
Sbjct 229 EWINK-HSGVVRNSAGSVAPDSAKCSGSGKPVR 260
Score = 63.5 bits (153), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 50/131 (38%), Positives = 64/131 (49%), Gaps = 0/131 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T L LT NQL+ LP F + + L L + N + L + KL L LNL HN+
Sbjct 85 TNLTYLILTGNQLQSLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTYLNLAHNQ 144
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L F TNLTEL L N +Q + F K L L L N L S G +L
Sbjct 145 LQSLPKGVFDKLTNLTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL 204
Query 171 ENLQELLLSNN 181
+LQ + L +N
Sbjct 205 TSLQYIWLHDN 215
Score = 62.8 bits (151), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 49/135 (36%), Positives = 70/135 (52%), Gaps = 2/135 (1%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
++L L L L N+L L + F TNL EL L+ N +Q + + F K NL L+L+
Sbjct 82 KELTNLTYLILTGNQLQSLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTYLNLA 141
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
HN L S G +L NL EL LS N++Q+L D + LK L L NQ+K G
Sbjct 142 HNQLQSLPKGVFDKLTNLTELDLSYNQLQSLPEGVFDKL--TQLKDLRLYQNQLKSVPDG 199
Query 216 CFHAIGRLFGLFLNN 230
F + L ++L++
Sbjct 200 VFDRLTSLQYIWLHD 214
Score = 59.3 bits (142), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 60/187 (32%), Positives = 88/187 (47%), Gaps = 5/187 (3%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L + N +
Sbjct 42 SIDQIIANNSDIKSVQGIQYLP-NVRYLALGGNKLHDISA--LKELTNLTYLILTGNQLQ 98
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLT L+L N +Q + F K N
Sbjct 99 SLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTYLNLAHNQLQSLPKGVFDKLTN 158
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
L LDLS+N L S G +L L++L L N+++++ D +SL+ + L N
Sbjct 159 LTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL--TSLQYIWLHDNP 216
Query 209 IKEFSPG 215
PG
Sbjct 217 WDCTCPG 223
Score = 43.5 bits (101), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 44/159 (28%), Positives = 71/159 (45%), Gaps = 31/159 (19%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L+L+ N++Q+L + D N LK+L L NQ++ G F +
Sbjct 83 ELTNLTYLILTGNQLQSLPNGVFDKLTN--LKELVLVENQLQSLPDGVFDKL-------- 132
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
T++ L+L+++QL + F K TNLT LDLSYN L
Sbjct 133 -------------------TNLTYLNLAHNQLQSLPKGVFD--KLTNLTELDLSYNQLQS 171
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
+ F L QL+ L N ++ + L +++Y+
Sbjct 172 LPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRLTSLQYI 210
Score = 35.8 bits (81), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 52/191 (27%), Positives = 85/191 (45%), Gaps = 26/191 (14%)
Query 306 EYNNIQHLFSH-----SLHG---LFNVRYLNLKRSFTKQSISLASLPKIDDFS-FQWLKC 356
E N+I + ++ S+ G L NVRYL L + K+ D S + L
Sbjct 39 ELNSIDQIIANNSDIKSVQGIQYLPNVRYLALGGN------------KLHDISALKELTN 86
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTK 416
L +L + N + + + +F L NLK L L + L++L + F L + L LNL
Sbjct 87 LTYLILTGNQLQSLPNGVFDKLTNLKELVLVEN--QLQSLPDGVFDKLTN--LTYLNLAH 142
Query 417 NKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSF 476
N++ + F L +L LDL N++ Q L + L + ++ L N+ + F
Sbjct 143 NQLQSLPKGVFDKLTNLTELDLSYNQL-QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVF 201
Query 477 ALVPSLQRLML 487
+ SLQ + L
Sbjct 202 DRLTSLQYIWL 212
>3rfs_B B Internalin B, repeat modules, Variable lymphocyte receptor
B
Length=272
Score = 75.5 bits (184), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 65/213 (31%), Positives = 99/213 (46%), Gaps = 16/213 (8%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L L L ++ S + L NLT L L+ N + ++ + + + L L+ L L
Sbjct 62 LPNVRYLALGGNKLHDI----SALKELTNLTYLILTGNQLQSLPNGVFDKLTNLKELVLV 117
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P L++L LNL N +P VF L L +DL N L
Sbjct 118 ENQLQSL--------PDGVFDKLTNLTYLNLAHNQLQSLPKGVFDKLTNLTELDLSYNQL 169
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L L +N + SV VF +L + + NP+DCTC I +
Sbjct 170 QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRYLS 228
Query 659 NWINETHTNIPELSSHYLC--NTPPHYHGFPVR 689
WIN+ H+ + S+ + + G PVR
Sbjct 229 EWINK-HSGVVRNSAGSVAPDSAKCSGSGKPVR 260
Score = 63.5 bits (153), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 50/131 (38%), Positives = 64/131 (49%), Gaps = 0/131 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T L LT NQL+ LP F + + L L + N + L + KL L LNL HN+
Sbjct 85 TNLTYLILTGNQLQSLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTYLNLAHNQ 144
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L F TNLTEL L N +Q + F K L L L N L S G +L
Sbjct 145 LQSLPKGVFDKLTNLTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL 204
Query 171 ENLQELLLSNN 181
+LQ + L +N
Sbjct 205 TSLQYIWLHDN 215
Score = 62.8 bits (151), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 49/135 (36%), Positives = 70/135 (52%), Gaps = 2/135 (1%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
++L L L L N+L L + F TNL EL L+ N +Q + + F K NL L+L+
Sbjct 82 KELTNLTYLILTGNQLQSLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTYLNLA 141
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
HN L S G +L NL EL LS N++Q+L D + LK L L NQ+K G
Sbjct 142 HNQLQSLPKGVFDKLTNLTELDLSYNQLQSLPEGVFDKL--TQLKDLRLYQNQLKSVPDG 199
Query 216 CFHAIGRLFGLFLNN 230
F + L ++L++
Sbjct 200 VFDRLTSLQYIWLHD 214
Score = 59.3 bits (142), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 60/187 (32%), Positives = 88/187 (47%), Gaps = 5/187 (3%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L + N +
Sbjct 42 SIDQIIANNSDIKSVQGIQYLP-NVRYLALGGNKLHDISA--LKELTNLTYLILTGNQLQ 98
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLT L+L N +Q + F K N
Sbjct 99 SLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTYLNLAHNQLQSLPKGVFDKLTN 158
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
L LDLS+N L S G +L L++L L N+++++ D +SL+ + L N
Sbjct 159 LTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL--TSLQYIWLHDNP 216
Query 209 IKEFSPG 215
PG
Sbjct 217 WDCTCPG 223
Score = 43.5 bits (101), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 44/159 (28%), Positives = 71/159 (45%), Gaps = 31/159 (19%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L+L+ N++Q+L + D N LK+L L NQ++ G F +
Sbjct 83 ELTNLTYLILTGNQLQSLPNGVFDKLTN--LKELVLVENQLQSLPDGVFDKL-------- 132
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
T++ L+L+++QL + F K TNLT LDLSYN L
Sbjct 133 -------------------TNLTYLNLAHNQLQSLPKGVFD--KLTNLTELDLSYNQLQS 171
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
+ F L QL+ L N ++ + L +++Y+
Sbjct 172 LPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRLTSLQYI 210
Score = 35.8 bits (81), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 52/191 (27%), Positives = 85/191 (45%), Gaps = 26/191 (14%)
Query 306 EYNNIQHLFSH-----SLHG---LFNVRYLNLKRSFTKQSISLASLPKIDDFS-FQWLKC 356
E N+I + ++ S+ G L NVRYL L + K+ D S + L
Sbjct 39 ELNSIDQIIANNSDIKSVQGIQYLPNVRYLALGGN------------KLHDISALKELTN 86
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTK 416
L +L + N + + + +F L NLK L L + L++L + F L + L LNL
Sbjct 87 LTYLILTGNQLQSLPNGVFDKLTNLKELVLVEN--QLQSLPDGVFDKLTN--LTYLNLAH 142
Query 417 NKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSF 476
N++ + F L +L LDL N++ Q L + L + ++ L N+ + F
Sbjct 143 NQLQSLPKGVFDKLTNLTELDLSYNQL-QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVF 201
Query 477 ALVPSLQRLML 487
+ SLQ + L
Sbjct 202 DRLTSLQYIWL 212
>4j4l_B B Internalin B,REPEAT MODULES,Variable lymphocyte receptor
B
Length=267
Score = 75.1 bits (183), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 60/190 (32%), Positives = 90/190 (47%), Gaps = 14/190 (7%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L L L ++ S + L NLT L L N + ++ + + + L L+ L L
Sbjct 55 LPNVRYLALGGNKLHDI----SALKELTNLTYLTLEPNQLQSLPNGVFDKLTNLKELQLW 110
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P L++L LNL N +P VF L L +DL N L
Sbjct 111 ANQLQSL--------PDGVFDKLTNLTYLNLAFNQLQSLPKGVFDKLTNLTELDLSYNQL 162
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L L +N + SV VF +L + + NP+DCTC I +
Sbjct 163 QSLPKGVFDKLTQLKDLRLYQNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRYLS 221
Query 659 NWINETHTNI 668
WIN+ H+ +
Sbjct 222 EWINK-HSGV 230
Score = 62.8 bits (151), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 48/135 (36%), Positives = 70/135 (52%), Gaps = 2/135 (1%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
++L L L L+ N+L L + F TNL EL L +N +Q + + F K NL L+L+
Sbjct 75 KELTNLTYLTLEPNQLQSLPNGVFDKLTNLKELQLWANQLQSLPDGVFDKLTNLTYLNLA 134
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L S G +L NL EL LS N++Q+L D + LK L L NQ+K G
Sbjct 135 FNQLQSLPKGVFDKLTNLTELDLSYNQLQSLPKGVFDKL--TQLKDLRLYQNQLKSVPDG 192
Query 216 CFHAIGRLFGLFLNN 230
F + L ++L++
Sbjct 193 VFDRLTSLQYIWLHD 207
Score = 61.6 bits (148), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 48/131 (37%), Positives = 62/131 (47%), Gaps = 0/131 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T L L NQL+ LP F + + L L + N + L + KL L LNL N+
Sbjct 78 TNLTYLTLEPNQLQSLPNGVFDKLTNLKELQLWANQLQSLPDGVFDKLTNLTYLNLAFNQ 137
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L F TNLTEL L N +Q + F K L L L N L S G +L
Sbjct 138 LQSLPKGVFDKLTNLTELDLSYNQLQSLPKGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL 197
Query 171 ENLQELLLSNN 181
+LQ + L +N
Sbjct 198 TSLQYIWLHDN 208
Score = 60.8 bits (146), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 60/187 (32%), Positives = 88/187 (47%), Gaps = 5/187 (3%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L + N +
Sbjct 35 SIDQIIANNSDIKSVQGIQYLP-NVRYLALGGNKLHDISA--LKELTNLTYLTLEPNQLQ 91
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLT L+L N +Q + F K N
Sbjct 92 SLPNGVFDKLTNLKELQLWANQLQSLPDGVFDKLTNLTYLNLAFNQLQSLPKGVFDKLTN 151
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
L LDLS+N L S G +L L++L L N+++++ D +SL+ + L N
Sbjct 152 LTELDLSYNQLQSLPKGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL--TSLQYIWLHDNP 209
Query 209 IKEFSPG 215
PG
Sbjct 210 WDCTCPG 216
Score = 41.2 bits (95), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 44/159 (28%), Positives = 70/159 (44%), Gaps = 31/159 (19%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L L N++Q+L + D N LK+L+L +NQ++ G F +
Sbjct 76 ELTNLTYLTLEPNQLQSLPNGVFDKLTN--LKELQLWANQLQSLPDGVFDKL-------- 125
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
T++ L+L+ +QL + F K TNLT LDLSYN L
Sbjct 126 -------------------TNLTYLNLAFNQLQSLPKGVFD--KLTNLTELDLSYNQLQS 164
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
+ F L QL+ L N ++ + L +++Y+
Sbjct 165 LPKGVFDKLTQLKDLRLYQNQLKSVPDGVFDRLTSLQYI 203
Score = 38.1 bits (87), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 53/191 (28%), Positives = 86/191 (45%), Gaps = 26/191 (14%)
Query 306 EYNNIQHLFSH-----SLHG---LFNVRYLNLKRSFTKQSISLASLPKIDDFS-FQWLKC 356
E N+I + ++ S+ G L NVRYL L + K+ D S + L
Sbjct 32 ELNSIDQIIANNSDIKSVQGIQYLPNVRYLALGGN------------KLHDISALKELTN 79
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTK 416
L +L +E N + + + +F L NLK L L + L++L + F L + L LNL
Sbjct 80 LTYLTLEPNQLQSLPNGVFDKLTNLKELQLWAN--QLQSLPDGVFDKLTN--LTYLNLAF 135
Query 417 NKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSF 476
N++ + F L +L LDL N++ Q L + L + ++ L N+ + F
Sbjct 136 NQLQSLPKGVFDKLTNLTELDLSYNQL-QSLPKGVFDKLTQLKDLRLYQNQLKSVPDGVF 194
Query 477 ALVPSLQRLML 487
+ SLQ + L
Sbjct 195 DRLTSLQYIWL 205
>4j4l_A A Internalin B,REPEAT MODULES,Variable lymphocyte receptor
B
Length=267
Score = 75.1 bits (183), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 60/190 (32%), Positives = 90/190 (47%), Gaps = 14/190 (7%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L L L ++ S + L NLT L L N + ++ + + + L L+ L L
Sbjct 55 LPNVRYLALGGNKLHDI----SALKELTNLTYLTLEPNQLQSLPNGVFDKLTNLKELQLW 110
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P L++L LNL N +P VF L L +DL N L
Sbjct 111 ANQLQSL--------PDGVFDKLTNLTYLNLAFNQLQSLPKGVFDKLTNLTELDLSYNQL 162
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L L +N + SV VF +L + + NP+DCTC I +
Sbjct 163 QSLPKGVFDKLTQLKDLRLYQNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRYLS 221
Query 659 NWINETHTNI 668
WIN+ H+ +
Sbjct 222 EWINK-HSGV 230
Score = 62.8 bits (151), Expect = 3e-09, Method: Compositional matrix adjust.
Identities = 48/135 (36%), Positives = 70/135 (52%), Gaps = 2/135 (1%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
++L L L L+ N+L L + F TNL EL L +N +Q + + F K NL L+L+
Sbjct 75 KELTNLTYLTLEPNQLQSLPNGVFDKLTNLKELQLWANQLQSLPDGVFDKLTNLTYLNLA 134
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L S G +L NL EL LS N++Q+L D + LK L L NQ+K G
Sbjct 135 FNQLQSLPKGVFDKLTNLTELDLSYNQLQSLPKGVFDKL--TQLKDLRLYQNQLKSVPDG 192
Query 216 CFHAIGRLFGLFLNN 230
F + L ++L++
Sbjct 193 VFDRLTSLQYIWLHD 207
Score = 61.2 bits (147), Expect = 8e-09, Method: Compositional matrix adjust.
Identities = 48/131 (37%), Positives = 62/131 (47%), Gaps = 0/131 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T L L NQL+ LP F + + L L + N + L + KL L LNL N+
Sbjct 78 TNLTYLTLEPNQLQSLPNGVFDKLTNLKELQLWANQLQSLPDGVFDKLTNLTYLNLAFNQ 137
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L F TNLTEL L N +Q + F K L L L N L S G +L
Sbjct 138 LQSLPKGVFDKLTNLTELDLSYNQLQSLPKGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL 197
Query 171 ENLQELLLSNN 181
+LQ + L +N
Sbjct 198 TSLQYIWLHDN 208
Score = 60.5 bits (145), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 60/187 (32%), Positives = 88/187 (47%), Gaps = 5/187 (3%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L + N +
Sbjct 35 SIDQIIANNSDIKSVQGIQYLP-NVRYLALGGNKLHDISA--LKELTNLTYLTLEPNQLQ 91
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLT L+L N +Q + F K N
Sbjct 92 SLPNGVFDKLTNLKELQLWANQLQSLPDGVFDKLTNLTYLNLAFNQLQSLPKGVFDKLTN 151
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
L LDLS+N L S G +L L++L L N+++++ D +SL+ + L N
Sbjct 152 LTELDLSYNQLQSLPKGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL--TSLQYIWLHDNP 209
Query 209 IKEFSPG 215
PG
Sbjct 210 WDCTCPG 216
Score = 41.6 bits (96), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 44/159 (28%), Positives = 70/159 (44%), Gaps = 31/159 (19%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L L N++Q+L + D N LK+L+L +NQ++ G F +
Sbjct 76 ELTNLTYLTLEPNQLQSLPNGVFDKLTN--LKELQLWANQLQSLPDGVFDKL-------- 125
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
T++ L+L+ +QL + F K TNLT LDLSYN L
Sbjct 126 -------------------TNLTYLNLAFNQLQSLPKGVFD--KLTNLTELDLSYNQLQS 164
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
+ F L QL+ L N ++ + L +++Y+
Sbjct 165 LPKGVFDKLTQLKDLRLYQNQLKSVPDGVFDRLTSLQYI 203
Score = 38.5 bits (88), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 53/191 (28%), Positives = 86/191 (45%), Gaps = 26/191 (14%)
Query 306 EYNNIQHLFSH-----SLHG---LFNVRYLNLKRSFTKQSISLASLPKIDDFS-FQWLKC 356
E N+I + ++ S+ G L NVRYL L + K+ D S + L
Sbjct 32 ELNSIDQIIANNSDIKSVQGIQYLPNVRYLALGGN------------KLHDISALKELTN 79
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTK 416
L +L +E N + + + +F L NLK L L + L++L + F L + L LNL
Sbjct 80 LTYLTLEPNQLQSLPNGVFDKLTNLKELQLWAN--QLQSLPDGVFDKLTN--LTYLNLAF 135
Query 417 NKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSF 476
N++ + F L +L LDL N++ Q L + L + ++ L N+ + F
Sbjct 136 NQLQSLPKGVFDKLTNLTELDLSYNQL-QSLPKGVFDKLTQLKDLRLYQNQLKSVPDGVF 194
Query 477 ALVPSLQRLML 487
+ SLQ + L
Sbjct 195 DRLTSLQYIWL 205
>8h6f_E Y Repebody (A6)
Length=267
Score = 75.1 bits (183), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 61/190 (32%), Positives = 94/190 (49%), Gaps = 14/190 (7%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L LR L ++ S + L NLT L L+ N + ++ + + + L L+ L L
Sbjct 63 LPNVRSLKLRSNKLHDI----SALKELTNLTFLFLNLNQLQSLPNGVFDKLTNLKELVLV 118
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P G L++L +L+L N +P VF L L +DL N L
Sbjct 119 ENQLQSL-----PDG---VFDKLTNLTLLHLMVNQLQSLPKGVFDKLTNLTELDLSYNQL 170
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L L +N + SV VF +L + + NP+DCTC I +
Sbjct 171 QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRYLS 229
Query 659 NWINETHTNI 668
WIN+ H+ +
Sbjct 230 EWINK-HSGV 238
Score = 63.2 bits (152), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 62/187 (33%), Positives = 87/187 (47%), Gaps = 5/187 (3%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ A S +K Q LP N+ L L N+L + A + LT L + N +
Sbjct 43 SIDQIYAPDSDIKSVQGIQYLP-NVRSLKLRSNKLHDISA--LKELTNLTFLFLNLNQLQ 99
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLT LHLM N +Q + F K N
Sbjct 100 SLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTLLHLMVNQLQSLPKGVFDKLTN 159
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
L LDLS+N L S G +L L++L L N+++++ D +SL+ + L N
Sbjct 160 LTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL--TSLQYIWLHDNP 217
Query 209 IKEFSPG 215
PG
Sbjct 218 WDCTCPG 224
Score = 39.7 bits (91), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 89/186 (48%), Gaps = 12/186 (6%)
Query 144 VKQKNLITLDLSHNGLSSTKLGTQVQ-LENLQELLLSNNKIQALKS-EELDIFANSSLKK 201
V Q L ++D + S K +Q L N++ L L +NK+ + + +EL ++L
Sbjct 36 VTQNELNSIDQIYAPDSDIKSVQGIQYLPNVRSLKLRSNKLHDISALKEL-----TNLTF 90
Query 202 LELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLS 261
L L+ NQ++ G F + L L L QL SL + + +L N ++ L L +QL
Sbjct 91 LFLNLNQLQSLPNGVFDKLTNLKELVLVENQLQ-SLPDGVFDKLTNLTL--LHLMVNQLQ 147
Query 262 TTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL 321
+ F K TNLT LDLSYN L + F L QL+ L N ++ + L
Sbjct 148 SLPKGVFD--KLTNLTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL 205
Query 322 FNVRYL 327
+++Y+
Sbjct 206 TSLQYI 211
>7yco_B B Repebody (A6)
Length=267
Score = 75.1 bits (183), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 61/190 (32%), Positives = 94/190 (49%), Gaps = 14/190 (7%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L LR L ++ S + L NLT L L+ N + ++ + + + L L+ L L
Sbjct 63 LPNVRSLKLRSNKLHDI----SALKELTNLTFLFLNLNQLQSLPNGVFDKLTNLKELVLV 118
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P G L++L +L+L N +P VF L L +DL N L
Sbjct 119 ENQLQSL-----PDG---VFDKLTNLTLLHLMVNQLQSLPKGVFDKLTNLTELDLSYNQL 170
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L L +N + SV VF +L + + NP+DCTC I +
Sbjct 171 QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRYLS 229
Query 659 NWINETHTNI 668
WIN+ H+ +
Sbjct 230 EWINK-HSGV 238
Score = 63.2 bits (152), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 62/187 (33%), Positives = 87/187 (47%), Gaps = 5/187 (3%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ A S +K Q LP N+ L L N+L + A + LT L + N +
Sbjct 43 SIDQIYAPDSDIKSVQGIQYLP-NVRSLKLRSNKLHDISA--LKELTNLTFLFLNLNQLQ 99
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLT LHLM N +Q + F K N
Sbjct 100 SLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTLLHLMVNQLQSLPKGVFDKLTN 159
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
L LDLS+N L S G +L L++L L N+++++ D +SL+ + L N
Sbjct 160 LTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL--TSLQYIWLHDNP 217
Query 209 IKEFSPG 215
PG
Sbjct 218 WDCTCPG 224
Score = 39.7 bits (91), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 89/186 (48%), Gaps = 12/186 (6%)
Query 144 VKQKNLITLDLSHNGLSSTKLGTQVQ-LENLQELLLSNNKIQALKS-EELDIFANSSLKK 201
V Q L ++D + S K +Q L N++ L L +NK+ + + +EL ++L
Sbjct 36 VTQNELNSIDQIYAPDSDIKSVQGIQYLPNVRSLKLRSNKLHDISALKEL-----TNLTF 90
Query 202 LELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLS 261
L L+ NQ++ G F + L L L QL SL + + +L N ++ L L +QL
Sbjct 91 LFLNLNQLQSLPNGVFDKLTNLKELVLVENQLQ-SLPDGVFDKLTNLTL--LHLMVNQLQ 147
Query 262 TTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL 321
+ F K TNLT LDLSYN L + F L QL+ L N ++ + L
Sbjct 148 SLPKGVFD--KLTNLTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL 205
Query 322 FNVRYL 327
+++Y+
Sbjct 206 TSLQYI 211
>8h6f_F Z Repebody (A6)
Length=267
Score = 75.1 bits (183), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 61/190 (32%), Positives = 94/190 (49%), Gaps = 14/190 (7%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L LR L ++ S + L NLT L L+ N + ++ + + + L L+ L L
Sbjct 63 LPNVRSLKLRSNKLHDI----SALKELTNLTFLFLNLNQLQSLPNGVFDKLTNLKELVLV 118
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P G L++L +L+L N +P VF L L +DL N L
Sbjct 119 ENQLQSL-----PDG---VFDKLTNLTLLHLMVNQLQSLPKGVFDKLTNLTELDLSYNQL 170
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L L +N + SV VF +L + + NP+DCTC I +
Sbjct 171 QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRYLS 229
Query 659 NWINETHTNI 668
WIN+ H+ +
Sbjct 230 EWINK-HSGV 238
Score = 63.2 bits (152), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 62/187 (33%), Positives = 87/187 (47%), Gaps = 5/187 (3%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ A S +K Q LP N+ L L N+L + A + LT L + N +
Sbjct 43 SIDQIYAPDSDIKSVQGIQYLP-NVRSLKLRSNKLHDISA--LKELTNLTFLFLNLNQLQ 99
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLT LHLM N +Q + F K N
Sbjct 100 SLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTLLHLMVNQLQSLPKGVFDKLTN 159
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
L LDLS+N L S G +L L++L L N+++++ D +SL+ + L N
Sbjct 160 LTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL--TSLQYIWLHDNP 217
Query 209 IKEFSPG 215
PG
Sbjct 218 WDCTCPG 224
Score = 39.7 bits (91), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 89/186 (48%), Gaps = 12/186 (6%)
Query 144 VKQKNLITLDLSHNGLSSTKLGTQVQ-LENLQELLLSNNKIQALKS-EELDIFANSSLKK 201
V Q L ++D + S K +Q L N++ L L +NK+ + + +EL ++L
Sbjct 36 VTQNELNSIDQIYAPDSDIKSVQGIQYLPNVRSLKLRSNKLHDISALKEL-----TNLTF 90
Query 202 LELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLS 261
L L+ NQ++ G F + L L L QL SL + + +L N ++ L L +QL
Sbjct 91 LFLNLNQLQSLPNGVFDKLTNLKELVLVENQLQ-SLPDGVFDKLTNLTL--LHLMVNQLQ 147
Query 262 TTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL 321
+ F K TNLT LDLSYN L + F L QL+ L N ++ + L
Sbjct 148 SLPKGVFD--KLTNLTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL 205
Query 322 FNVRYL 327
+++Y+
Sbjct 206 TSLQYI 211
>8h6f_D X Repebody (A6)
Length=267
Score = 75.1 bits (183), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 61/190 (32%), Positives = 94/190 (49%), Gaps = 14/190 (7%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L LR L ++ S + L NLT L L+ N + ++ + + + L L+ L L
Sbjct 63 LPNVRSLKLRSNKLHDI----SALKELTNLTFLFLNLNQLQSLPNGVFDKLTNLKELVLV 118
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P G L++L +L+L N +P VF L L +DL N L
Sbjct 119 ENQLQSL-----PDG---VFDKLTNLTLLHLMVNQLQSLPKGVFDKLTNLTELDLSYNQL 170
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L L +N + SV VF +L + + NP+DCTC I +
Sbjct 171 QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRYLS 229
Query 659 NWINETHTNI 668
WIN+ H+ +
Sbjct 230 EWINK-HSGV 238
Score = 63.2 bits (152), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 62/187 (33%), Positives = 87/187 (47%), Gaps = 5/187 (3%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ A S +K Q LP N+ L L N+L + A + LT L + N +
Sbjct 43 SIDQIYAPDSDIKSVQGIQYLP-NVRSLKLRSNKLHDISA--LKELTNLTFLFLNLNQLQ 99
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLT LHLM N +Q + F K N
Sbjct 100 SLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTLLHLMVNQLQSLPKGVFDKLTN 159
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
L LDLS+N L S G +L L++L L N+++++ D +SL+ + L N
Sbjct 160 LTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL--TSLQYIWLHDNP 217
Query 209 IKEFSPG 215
PG
Sbjct 218 WDCTCPG 224
Score = 39.7 bits (91), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 89/186 (48%), Gaps = 12/186 (6%)
Query 144 VKQKNLITLDLSHNGLSSTKLGTQVQ-LENLQELLLSNNKIQALKS-EELDIFANSSLKK 201
V Q L ++D + S K +Q L N++ L L +NK+ + + +EL ++L
Sbjct 36 VTQNELNSIDQIYAPDSDIKSVQGIQYLPNVRSLKLRSNKLHDISALKEL-----TNLTF 90
Query 202 LELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLS 261
L L+ NQ++ G F + L L L QL SL + + +L N ++ L L +QL
Sbjct 91 LFLNLNQLQSLPNGVFDKLTNLKELVLVENQLQ-SLPDGVFDKLTNLTL--LHLMVNQLQ 147
Query 262 TTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGL 321
+ F K TNLT LDLSYN L + F L QL+ L N ++ + L
Sbjct 148 SLPKGVFD--KLTNLTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL 205
Query 322 FNVRYL 327
+++Y+
Sbjct 206 TSLQYI 211
>2z64_A A Toll-like receptor 4
Length=599
Score = 77.8 bits (190), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 160/674 (24%), Positives = 274/674 (41%), Gaps = 101/674 (15%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL++VPDD+P++ ++L+ N L+ L + +F+ +S+L LD+ I +E +
Sbjct 13 CMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH 72
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + S +F+ T+L L + + +++ P + L L+++H
Sbjct 73 GLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAH 132
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLK--KLELSSNQIKEFS 213
N + S KL L NL + LS N IQ + +L + L++S N I
Sbjct 133 NFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQ 192
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
F I +L L L S K CL+ LA + L L L +
Sbjct 193 DQAFQGI-KLHELTLRG-NFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIM 250
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL- 327
GL + L+Y N ++++ + ++ + SL G+ +++YL
Sbjct 251 EGLCDVTIDEFRLTYTN-------------DFSDDIVKFHCLANVSAMSLAGV-SIKYLE 296
Query 328 NLKRSFTKQSISL--ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
++ + F QS+S+ L + +LK L L M I K L +L YL
Sbjct 297 DVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLT-LTMNKGSISFKK----VALPSLSYLD 351
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS + S ++ L + L L+L+ N + I S F L L+ LD + + +
Sbjct 352 LSRNALSFSGCC--SYSDLGTNSLRHLDLSFNG-AIIMSANFMGLEELQHLDFQHSTLKR 408
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+ LE + + +SY F + SL L + + K+ ++ + F
Sbjct 409 VTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKD-NTLSNVFANT 467
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT LDLS + I+ + + L +L++L++ HNNL
Sbjct 468 TNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNL----------------------- 504
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L L+S+ +++ L+ L +D N + T K ++
Sbjct 505 -LFLDSSHYNQ--------LYSLSTLDCSFNRIET-----------------SKGILQHF 538
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETH---TNIPELSSHYLCNTPPH 682
K + AF NLT N C CE F+ W+ E N+ +++ C TP
Sbjct 539 PKSL---AFFNLTN-----NSVACICEH-QKFLQWVKEQKQFLVNVEQMT----CATPVE 585
Query 683 YHGFPVRLFDTSSC 696
+ V F+ S+C
Sbjct 586 MNTSLVLDFNNSTC 599
>2mka_B B Toll-like receptor 3
Length=34
Score = 68.2 bits (165), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 33/33 (100%), Positives = 33/33 (100%), Gaps = 0/33 (0%)
Query 698 DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI 730
DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI
Sbjct 2 DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI 34
>2mka_A A Toll-like receptor 3
Length=34
Score = 68.2 bits (165), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 33/33 (100%), Positives = 33/33 (100%), Gaps = 0/33 (0%)
Query 698 DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI 730
DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI
Sbjct 2 DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI 34
>2mka_C C Toll-like receptor 3
Length=34
Score = 68.2 bits (165), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 33/33 (100%), Positives = 33/33 (100%), Gaps = 0/33 (0%)
Query 698 DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI 730
DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI
Sbjct 2 DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI 34
>2mk9_B B Toll-like receptor 3
Length=34
Score = 68.2 bits (165), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 33/33 (100%), Positives = 33/33 (100%), Gaps = 0/33 (0%)
Query 698 DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI 730
DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI
Sbjct 2 DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI 34
>2mk9_A A Toll-like receptor 3
Length=34
Score = 68.2 bits (165), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 33/33 (100%), Positives = 33/33 (100%), Gaps = 0/33 (0%)
Query 698 DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI 730
DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI
Sbjct 2 DSAPFELFFMINTSILLIFIFIVLLIHFEGWRI 34
>3vq1_C B Toll-like receptor 4
Length=606
Score = 77.4 bits (189), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 160/674 (24%), Positives = 274/674 (41%), Gaps = 101/674 (15%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL++VPDD+P++ ++L+ N L+ L + +F+ +S+L LD+ I +E +
Sbjct 18 CMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH 77
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + S +F+ T+L L + + +++ P + L L+++H
Sbjct 78 GLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAH 137
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLK--KLELSSNQIKEFS 213
N + S KL L NL + LS N IQ + +L + L++S N I
Sbjct 138 NFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQ 197
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
F I +L L L S K CL+ LA + L L L +
Sbjct 198 DQAFQGI-KLHELTLRG-NFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIM 255
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL- 327
GL + L+Y N ++++ + ++ + SL G+ +++YL
Sbjct 256 EGLCDVTIDEFRLTYTN-------------DFSDDIVKFHCLANVSAMSLAGV-SIKYLE 301
Query 328 NLKRSFTKQSISL--ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
++ + F QS+S+ L + +LK L L M I K L +L YL
Sbjct 302 DVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLT-LTMNKGSISFKK----VALPSLSYLD 356
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS + S ++ L + L L+L+ N + I S F L L+ LD + + +
Sbjct 357 LSRNALSFSGCC--SYSDLGTNSLRHLDLSFNG-AIIMSANFMGLEELQHLDFQHSTLKR 413
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+ LE + + +SY F + SL L + + K+ ++ + F
Sbjct 414 VTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKD-NTLSNVFANT 472
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT LDLS + I+ + + L +L++L++ HNNL
Sbjct 473 TNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNL----------------------- 509
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L L+S+ +++ L+ L +D N + T K ++
Sbjct 510 -LFLDSSHYNQ--------LYSLSTLDCSFNRIET-----------------SKGILQHF 543
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETH---TNIPELSSHYLCNTPPH 682
K + AF NLT N C CE F+ W+ E N+ +++ C TP
Sbjct 544 PKSL---AFFNLTN-----NSVACICEH-QKFLQWVKEQKQFLVNVEQMT----CATPXX 590
Query 683 YHGFPVRLFDTSSC 696
+ V F+ S+C
Sbjct 591 XNTSLVLDFNNSTC 604
>3vq1_A A Toll-like receptor 4
Length=606
Score = 77.4 bits (189), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 160/674 (24%), Positives = 274/674 (41%), Gaps = 101/674 (15%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL++VPDD+P++ ++L+ N L+ L + +F+ +S+L LD+ I +E +
Sbjct 18 CMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH 77
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + S +F+ T+L L + + +++ P + L L+++H
Sbjct 78 GLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAH 137
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLK--KLELSSNQIKEFS 213
N + S KL L NL + LS N IQ + +L + L++S N I
Sbjct 138 NFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQ 197
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
F I +L L L S K CL+ LA + L L L +
Sbjct 198 DQAFQGI-KLHELTLRG-NFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIM 255
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL- 327
GL + L+Y N ++++ + ++ + SL G+ +++YL
Sbjct 256 EGLCDVTIDEFRLTYTN-------------DFSDDIVKFHCLANVSAMSLAGV-SIKYLE 301
Query 328 NLKRSFTKQSISL--ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
++ + F QS+S+ L + +LK L L M I K L +L YL
Sbjct 302 DVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLT-LTMNKGSISFKK----VALPSLSYLD 356
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS + S ++ L + L L+L+ N + I S F L L+ LD + + +
Sbjct 357 LSRNALSFSGCC--SYSDLGTNSLRHLDLSFNG-AIIMSANFMGLEELQHLDFQHSTLKR 413
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+ LE + + +SY F + SL L + + K+ ++ + F
Sbjct 414 VTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKD-NTLSNVFANT 472
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT LDLS + I+ + + L +L++L++ HNNL
Sbjct 473 TNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNL----------------------- 509
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L L+S+ +++ L+ L +D N + T K ++
Sbjct 510 -LFLDSSHYNQ--------LYSLSTLDCSFNRIET-----------------SKGILQHF 543
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETH---TNIPELSSHYLCNTPPH 682
K + AF NLT N C CE F+ W+ E N+ +++ C TP
Sbjct 544 PKSL---AFFNLTN-----NSVACICEH-QKFLQWVKEQKQFLVNVEQMT----CATPXX 590
Query 683 YHGFPVRLFDTSSC 696
+ V F+ S+C
Sbjct 591 XNTSLVLDFNNSTC 604
>6htf_B B rF10 repebody
Length=274
Score = 74.7 bits (182), Expect = 3e-13, Method: Compositional matrix adjust.
Identities = 60/190 (32%), Positives = 93/190 (49%), Gaps = 14/190 (7%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L L L ++ S + L NLT L+L N + ++ + + + L L+ L L
Sbjct 62 LPNVRYLALGGYKLHDI----SALKELTNLTYLELIYNQLQSLPNGVFDKLTNLKELVLY 117
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P G L L++L+ L+ N +P VF L L +DL N L
Sbjct 118 WNQLQSL-----PDGVFDKLTNLTYLY---LQRNQLQSLPKGVFDKLTNLTELDLSYNQL 169
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L L +N + SV VF +L + + NP+DCTC I +
Sbjct 170 QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRYLS 228
Query 659 NWINETHTNI 668
WIN+ H+ +
Sbjct 229 EWINK-HSGV 237
Score = 63.9 bits (154), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 48/131 (37%), Positives = 64/131 (49%), Gaps = 0/131 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T L L +NQL+ LP F + + L L + +N + L + KL L L LQ N+
Sbjct 85 TNLTYLELIYNQLQSLPNGVFDKLTNLKELVLYWNQLQSLPDGVFDKLTNLTYLYLQRNQ 144
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L F TNLTEL L N +Q + F K L L L N L S G +L
Sbjct 145 LQSLPKGVFDKLTNLTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL 204
Query 171 ENLQELLLSNN 181
+LQ + L +N
Sbjct 205 TSLQYIWLHDN 215
Score = 61.6 bits (148), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 59/187 (32%), Positives = 89/187 (48%), Gaps = 5/187 (3%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L +L + A + LT L++ +N +
Sbjct 42 SIDQIIANNSDIKSVQGIQYLP-NVRYLALGGYKLHDISA--LKELTNLTYLELIYNQLQ 98
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLT L+L N +Q + F K N
Sbjct 99 SLPNGVFDKLTNLKELVLYWNQLQSLPDGVFDKLTNLTYLYLQRNQLQSLPKGVFDKLTN 158
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
L LDLS+N L S G +L L++L L N+++++ D +SL+ + L N
Sbjct 159 LTELDLSYNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL--TSLQYIWLHDNP 216
Query 209 IKEFSPG 215
PG
Sbjct 217 WDCTCPG 223
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 51/163 (31%), Positives = 71/163 (44%), Gaps = 14/163 (9%)
Query 249 SIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
++R L+L +L S L TNLT L+L YN L + N F L L+ L +N
Sbjct 64 NVRYLALGGYKLHDISALKEL----TNLTYLELIYNQLQSLPNGVFDKLTNLKELVLYWN 119
Query 309 NIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIP 368
+Q L L N+ YL L+R+ L SLPK F L L L++ N +
Sbjct 120 QLQSLPDGVFDKLTNLTYLYLQRN------QLQSLPK---GVFDKLTNLTELDLSYNQLQ 170
Query 369 GIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLH 410
+ +F L LK L L N S+ + SL + LH
Sbjct 171 SLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRLTSLQYIWLH 213
Score = 40.0 bits (92), Expect = 0.068, Method: Compositional matrix adjust.
Identities = 47/140 (34%), Positives = 66/140 (47%), Gaps = 7/140 (5%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L L N++Q+L + D N LK+L L NQ++ G F + L L+L
Sbjct 83 ELTNLTYLELIYNQLQSLPNGVFDKLTN--LKELVLYWNQLQSLPDGVFDKLTNLTYLYL 140
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
QL SL + + +L N + L LS +QL + F K T L L L N L
Sbjct 141 QRNQLQ-SLPKGVFDKLTN--LTELDLSYNQLQSLPEGVF--DKLTQLKDLRLYQNQLKS 195
Query 289 VGNDSFAWLPQLEYFFLEYN 308
V + F L L+Y +L N
Sbjct 196 VPDGVFDRLTSLQYIWLHDN 215
>5hdh_A A Toll-like receptor 8
Length=801
Score = 77.4 bits (189), Expect = 4e-13, Method: Compositional matrix adjust.
Identities = 192/814 (24%), Positives = 304/814 (37%), Gaps = 188/814 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 79
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 80 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 136
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 137 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 195
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 196 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 243
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 244 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 301
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 302 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 356
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNET 400
+ DDF L L +N+ N I I +F NL+ + LS N + L
Sbjct 357 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 414
Query 401 FVSLAHSPLHI----------------------------------LNLTKNKISKIESDA 426
+ + HI L+L+ N I I +
Sbjct 415 XXNSSSFQRHIXXXXXXXXXXXPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 474
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 475 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 526
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 527 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 586
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 587 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 644
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 645 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 704
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 705 FLXXXSSLKHLDLSSNLLKTINKSALXXXXXXKLSMLELHGNPFECTCD-IGDFRRWMDE 763
Query 664 -THTNIPELSSHYLCNTPPHYHGFPVRLFDTSSC 696
+ IP L +C +P G + + ++C
Sbjct 764 HLNVKIPRLVD-VICASPGDQRGKSIVSLELTTC 796
>3vq2_A A Toll-like receptor 4
Length=606
Score = 76.6 bits (187), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 130/517 (25%), Positives = 224/517 (43%), Gaps = 36/517 (7%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL++VPDD+P++ ++L+ N L+ L + +F+ +S+L LD+ I +E +
Sbjct 18 CMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH 77
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + S +F+ T+L L + + +++ P + L L+++H
Sbjct 78 GLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAH 137
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLK--KLELSSNQIKEFS 213
N + S KL L NL + LS N IQ + +L + L++S N I
Sbjct 138 NFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQ 197
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
F I +L L L S K CL+ LA + L L L +
Sbjct 198 DQAFQGI-KLHELTLRG-NFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIM 255
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL- 327
GL + L+Y N ++++ + ++ + SL G+ +++YL
Sbjct 256 EGLCDVTIDEFRLTYTN-------------DFSDDIVKFHCLANVSAMSLAGV-SIKYLE 301
Query 328 NLKRSFTKQSISL--ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
++ + F QS+S+ L + +LK L L M I K L +L YL
Sbjct 302 DVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLT-LTMNKGSISFKK----VALPSLSYLD 356
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS + S ++ L + L L+L+ N + I S F L L+ LD + + +
Sbjct 357 LSRNALSFSGCC--SYSDLGTNSLRHLDLSFNG-AIIMSANFMGLEELQHLDFQHSTLKR 413
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+ LE + + +SY F + SL L + + K+ ++ + F
Sbjct 414 VTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKD-NTLSNVFANT 472
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
NLT LDLS + I+ + + L +L++L++ HNNL
Sbjct 473 TNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNL 509
>3vq2_C B Toll-like receptor 4
Length=606
Score = 76.6 bits (187), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 130/517 (25%), Positives = 224/517 (43%), Gaps = 36/517 (7%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL++VPDD+P++ ++L+ N L+ L + +F+ +S+L LD+ I +E +
Sbjct 18 CMDQKLSKVPDDIPSSTKNIDLSFNPLKILKSYSFSNFSELQWLDLSRCEIETIEDKAWH 77
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + S +F+ T+L L + + +++ P + L L+++H
Sbjct 78 GLHHLSNLILTGNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLITLKKLNVAH 137
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLK--KLELSSNQIKEFS 213
N + S KL L NL + LS N IQ + +L + L++S N I
Sbjct 138 NFIHSCKLPAYFSNLTNLVHVDLSYNYIQTITVNDLQFLRENPQVNLSLDMSLNPIDFIQ 197
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNLSLS----NSQLSTTSNTTF 268
F I +L L L S K CL+ LA + L L L +
Sbjct 198 DQAFQGI-KLHELTLRG-NFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLEIFEPSIM 255
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL- 327
GL + L+Y N ++++ + ++ + SL G+ +++YL
Sbjct 256 EGLCDVTIDEFRLTYTN-------------DFSDDIVKFHCLANVSAMSLAGV-SIKYLE 301
Query 328 NLKRSFTKQSISL--ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
++ + F QS+S+ L + +LK L L M I K L +L YL
Sbjct 302 DVPKHFKWQSLSIIRCQLKQFPTLDLPFLKSLT-LTMNKGSISFKK----VALPSLSYLD 356
Query 386 LSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
LS + S ++ L + L L+L+ N + I S F L L+ LD + + +
Sbjct 357 LSRNALSFSGCC--SYSDLGTNSLRHLDLSFNG-AIIMSANFMGLEELQHLDFQHSTLKR 413
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
+ LE + + +SY F + SL L + + K+ ++ + F
Sbjct 414 VTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLTSLNTLKMAGNSFKD-NTLSNVFANT 472
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
NLT LDLS + I+ + + L +L++L++ HNNL
Sbjct 473 TNLTFLDLSKCQLEQISWGVFDTLHRLQLLNMSHNNL 509
>2id5_C C Leucine rich repeat neuronal 6A
Length=477
Score = 76.3 bits (186), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 84/364 (23%), Positives = 151/364 (41%), Gaps = 42/364 (12%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+ C + VP+ +PT +L+L N+++ L F + L L++ N
Sbjct 8 ECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENI 67
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+S +EP L L+ L L+ N L + F +NLT+L + N I + + F
Sbjct 68 VSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDL 127
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE-LS 205
NL +L++ N L L +L++L L + ++ +E L + +L L+
Sbjct 128 YNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLN 187
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
N I+++S RL+ L + + P L T +
Sbjct 188 INAIRDYS------FKRLYRLKVLEISHWP-----------------------YLDTMTP 218
Query 266 TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVR 325
GL NLT L +++ NL V + L L + L YN I + LH L ++
Sbjct 219 NCLYGL---NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQ 275
Query 326 YLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
+ L L ++ ++F+ L L LN+ N + ++ ++F + NL+ L
Sbjct 276 EIQLVG---------GQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLI 326
Query 386 LSNS 389
L ++
Sbjct 327 LDSN 330
Score = 67.8 bits (164), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 90/344 (26%), Positives = 147/344 (43%), Gaps = 62/344 (18%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
T +LDL N + + D FA P LE L N + + + + LFN+R L L+ +
Sbjct 32 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 91
Query 334 TK-----QSISLASLPKID----------DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGL 378
K L++L K+D D+ FQ L L+ L + DND+ I F+GL
Sbjct 92 LKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGL 151
Query 379 INLKYLSLSNSFTSLRTLTNETFVSLAH-SPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
+L+ L+L LT+ +L+H L +L L I+ I +F L L+VL+
Sbjct 152 NSLEQLTLEKC-----NLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE 206
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS 497
+ W L+ +T N L L L +++ + +
Sbjct 207 I-----------SHWPYLDT-------------MTPN------CLYGLNLTSLSITHCNL 236
Query 498 SPSPFQPLRNLT---ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGP 554
+ P+ +R+L L+LS N I+ I ML L +L+ + L LA + +A
Sbjct 237 TAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYA----- 291
Query 555 IYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+GL++L +LN+ N + VF + L+ + L N L
Sbjct 292 ---FRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 332
Score = 53.5 bits (127), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 57/208 (27%), Positives = 83/208 (40%), Gaps = 35/208 (17%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L+L KN+I + D F+ HLE L+L N + + E N+F + + L
Sbjct 35 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIV----SAVEPGAFNNLFNL-----RTL 85
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L N L+P F L NLT LD+S N I + D M + L
Sbjct 86 GLRSNRLKLIPL------------------GVFTGLSNLTKLDISENKIVILLDYMFQDL 127
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
L+ L++ N+L + A GL+ L L LE IP E L L
Sbjct 128 YNLKSLEVGDNDLVYISHRA--------FSGLNSLEQLTLEKCNLTSIPTEALSHLHGLI 179
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNL 617
++ L N+N + F LK L +
Sbjct 180 VLRLRHLNINAIRDYSFKRLYRLKVLEI 207
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 36/121 (30%), Positives = 52/121 (43%), Gaps = 8/121 (7%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+LDL N I +N D LE L+L N + PG L +L L L
Sbjct 36 LLDLGKNRIKTLNQDEFASFPHLEELELNEN----IVSAVEPGA----FNNLFNLRTLGL 87
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN IP+ VF L L +D+ N + L +F + +LKSL + N + + +
Sbjct 88 RSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRA 147
Query 630 F 630
F
Sbjct 148 F 148
Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 29/109 (27%), Positives = 51/109 (47%), Gaps = 0/109 (0%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+T L++TH L +P L L++ +N IS +E + +L L+ + L +L
Sbjct 225 NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQL 284
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+ + F L L++ N + ++ + F NL TL L N L+
Sbjct 285 AVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLA 333
Score = 34.3 bits (77), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 21/59 (36%), Positives = 33/59 (56%), Gaps = 1/59 (2%)
Query 587 ELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
E +++DLG N + TL F + L+ L L +N++++VE F F NL L +R N
Sbjct 33 ETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLF-NLRTLGLRSN 90
>2id5_A A Leucine rich repeat neuronal 6A
Length=477
Score = 76.3 bits (186), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 84/364 (23%), Positives = 151/364 (41%), Gaps = 42/364 (12%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+ C + VP+ +PT +L+L N+++ L F + L L++ N
Sbjct 8 ECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENI 67
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+S +EP L L+ L L+ N L + F +NLT+L + N I + + F
Sbjct 68 VSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDL 127
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE-LS 205
NL +L++ N L L +L++L L + ++ +E L + +L L+
Sbjct 128 YNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLN 187
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
N I+++S RL+ L + + P L T +
Sbjct 188 INAIRDYS------FKRLYRLKVLEISHWP-----------------------YLDTMTP 218
Query 266 TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVR 325
GL NLT L +++ NL V + L L + L YN I + LH L ++
Sbjct 219 NCLYGL---NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQ 275
Query 326 YLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
+ L L ++ ++F+ L L LN+ N + ++ ++F + NL+ L
Sbjct 276 EIQLVG---------GQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLI 326
Query 386 LSNS 389
L ++
Sbjct 327 LDSN 330
Score = 68.2 bits (165), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 90/344 (26%), Positives = 147/344 (43%), Gaps = 62/344 (18%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
T +LDL N + + D FA P LE L N + + + + LFN+R L L+ +
Sbjct 32 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 91
Query 334 TK-----QSISLASLPKID----------DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGL 378
K L++L K+D D+ FQ L L+ L + DND+ I F+GL
Sbjct 92 LKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGL 151
Query 379 INLKYLSLSNSFTSLRTLTNETFVSLAH-SPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
+L+ L+L LT+ +L+H L +L L I+ I +F L L+VL+
Sbjct 152 NSLEQLTLEKC-----NLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE 206
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS 497
+ W L+ +T N L L L +++ + +
Sbjct 207 I-----------SHWPYLDT-------------MTPN------CLYGLNLTSLSITHCNL 236
Query 498 SPSPFQPLRNLT---ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGP 554
+ P+ +R+L L+LS N I+ I ML L +L+ + L LA + +A
Sbjct 237 TAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYA----- 291
Query 555 IYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+GL++L +LN+ N + VF + L+ + L N L
Sbjct 292 ---FRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 332
Score = 53.5 bits (127), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 57/208 (27%), Positives = 83/208 (40%), Gaps = 35/208 (17%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L+L KN+I + D F+ HLE L+L N + + E N+F + + L
Sbjct 35 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIV----SAVEPGAFNNLFNL-----RTL 85
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L N L+P F L NLT LD+S N I + D M + L
Sbjct 86 GLRSNRLKLIPL------------------GVFTGLSNLTKLDISENKIVILLDYMFQDL 127
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
L+ L++ N+L + A GL+ L L LE IP E L L
Sbjct 128 YNLKSLEVGDNDLVYISHRA--------FSGLNSLEQLTLEKCNLTSIPTEALSHLHGLI 179
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNL 617
++ L N+N + F LK L +
Sbjct 180 VLRLRHLNINAIRDYSFKRLYRLKVLEI 207
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 36/121 (30%), Positives = 52/121 (43%), Gaps = 8/121 (7%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+LDL N I +N D LE L+L N + PG L +L L L
Sbjct 36 LLDLGKNRIKTLNQDEFASFPHLEELELNEN----IVSAVEPGA----FNNLFNLRTLGL 87
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN IP+ VF L L +D+ N + L +F + +LKSL + N + + +
Sbjct 88 RSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRA 147
Query 630 F 630
F
Sbjct 148 F 148
Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 29/109 (27%), Positives = 51/109 (47%), Gaps = 0/109 (0%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+T L++TH L +P L L++ +N IS +E + +L L+ + L +L
Sbjct 225 NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQL 284
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+ + F L L++ N + ++ + F NL TL L N L+
Sbjct 285 AVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLA 333
Score = 34.3 bits (77), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 21/59 (36%), Positives = 33/59 (56%), Gaps = 1/59 (2%)
Query 587 ELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
E +++DLG N + TL F + L+ L L +N++++VE F F NL L +R N
Sbjct 33 ETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLF-NLRTLGLRSN 90
>2v9s_A A SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Length=224
Score = 72.8 bits (177), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 50/154 (32%), Positives = 78/154 (51%), Gaps = 0/154 (0%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
CT S+ + DC LT++P +LP IT + L N ++ +P F+ Y +L +D+ N I
Sbjct 9 CTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQI 68
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
S+L P+ Q L L L L N++++L F +L L L +N I ++ + F
Sbjct 69 SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINXLRVDAFQDLH 128
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
NL L L N L + GT L +Q + L+ N
Sbjct 129 NLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 162
Score = 54.7 bits (130), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 50/173 (29%), Positives = 81/173 (47%), Gaps = 14/173 (8%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
+T + L N I I +KL +DL +N ++ L A +GL L+ L
Sbjct 34 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA--------FQGLRSLNSL 85
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L N E+P +F+ LF L+++ L N +N L F + +L L+L N + ++ K
Sbjct 86 VLYGNKITELPKSLFEGLFSLQLLLLNANKINXLRVDAFQDLHNLNLLSLYDNKLQTIAK 145
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTP 680
F P R + + + NPF C C + W +++ HTN P +S C +P
Sbjct 146 GTFSP-LRAIQTMHLAQNPFICDCH-LKWLADYL---HTN-PIETSGARCTSP 192
Score = 37.4 bits (85), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 37/131 (28%), Positives = 58/131 (44%), Gaps = 7/131 (5%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
+ L +N I I AFS L +DL N+I EL ++GL ++ + L NK +L
Sbjct 37 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQIS-ELAPDAFQGLRSLNSLVLYGNKITEL 95
Query 472 TRNSF--ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
++ F L L ++ VD+ FQ L NL +L L +N + I L
Sbjct 96 PKSLFEGLFSLQLLLLNANKINXLRVDA----FQDLHNLNLLSLYDNKLQTIAKGTFSPL 151
Query 530 EKLEILDLQHN 540
++ + L N
Sbjct 152 RAIQTMHLAQN 162
>2v9s_C C SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Length=224
Score = 72.8 bits (177), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 50/154 (32%), Positives = 78/154 (51%), Gaps = 0/154 (0%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
CT S+ + DC LT++P +LP IT + L N ++ +P F+ Y +L +D+ N I
Sbjct 9 CTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQI 68
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
S+L P+ Q L L L L N++++L F +L L L +N I ++ + F
Sbjct 69 SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINXLRVDAFQDLH 128
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
NL L L N L + GT L +Q + L+ N
Sbjct 129 NLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 162
Score = 54.7 bits (130), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 50/173 (29%), Positives = 81/173 (47%), Gaps = 14/173 (8%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
+T + L N I I +KL +DL +N ++ L A +GL L+ L
Sbjct 34 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA--------FQGLRSLNSL 85
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L N E+P +F+ LF L+++ L N +N L F + +L L+L N + ++ K
Sbjct 86 VLYGNKITELPKSLFEGLFSLQLLLLNANKINXLRVDAFQDLHNLNLLSLYDNKLQTIAK 145
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTP 680
F P R + + + NPF C C + W +++ HTN P +S C +P
Sbjct 146 GTFSP-LRAIQTMHLAQNPFICDCH-LKWLADYL---HTN-PIETSGARCTSP 192
Score = 37.4 bits (85), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 37/131 (28%), Positives = 58/131 (44%), Gaps = 7/131 (5%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
+ L +N I I AFS L +DL N+I EL ++GL ++ + L NK +L
Sbjct 37 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQIS-ELAPDAFQGLRSLNSLVLYGNKITEL 95
Query 472 TRNSF--ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
++ F L L ++ VD+ FQ L NL +L L +N + I L
Sbjct 96 PKSLFEGLFSLQLLLLNANKINXLRVDA----FQDLHNLNLLSLYDNKLQTIAKGTFSPL 151
Query 530 EKLEILDLQHN 540
++ + L N
Sbjct 152 RAIQTMHLAQN 162
>2v9s_D D SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Length=224
Score = 72.8 bits (177), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 50/154 (32%), Positives = 78/154 (51%), Gaps = 0/154 (0%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
CT S+ + DC LT++P +LP IT + L N ++ +P F+ Y +L +D+ N I
Sbjct 9 CTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQI 68
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
S+L P+ Q L L L L N++++L F +L L L +N I ++ + F
Sbjct 69 SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINXLRVDAFQDLH 128
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
NL L L N L + GT L +Q + L+ N
Sbjct 129 NLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 162
Score = 54.7 bits (130), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 50/173 (29%), Positives = 81/173 (47%), Gaps = 14/173 (8%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
+T + L N I I +KL +DL +N ++ L A +GL L+ L
Sbjct 34 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA--------FQGLRSLNSL 85
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L N E+P +F+ LF L+++ L N +N L F + +L L+L N + ++ K
Sbjct 86 VLYGNKITELPKSLFEGLFSLQLLLLNANKINXLRVDAFQDLHNLNLLSLYDNKLQTIAK 145
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTP 680
F P R + + + NPF C C + W +++ HTN P +S C +P
Sbjct 146 GTFSP-LRAIQTMHLAQNPFICDCH-LKWLADYL---HTN-PIETSGARCTSP 192
Score = 37.4 bits (85), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 37/131 (28%), Positives = 58/131 (44%), Gaps = 7/131 (5%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
+ L +N I I AFS L +DL N+I EL ++GL ++ + L NK +L
Sbjct 37 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQIS-ELAPDAFQGLRSLNSLVLYGNKITEL 95
Query 472 TRNSF--ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
++ F L L ++ VD+ FQ L NL +L L +N + I L
Sbjct 96 PKSLFEGLFSLQLLLLNANKINXLRVDA----FQDLHNLNLLSLYDNKLQTIAKGTFSPL 151
Query 530 EKLEILDLQHN 540
++ + L N
Sbjct 152 RAIQTMHLAQN 162
>2v9s_B B SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Length=224
Score = 72.8 bits (177), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 50/154 (32%), Positives = 78/154 (51%), Gaps = 0/154 (0%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
CT S+ + DC LT++P +LP IT + L N ++ +P F+ Y +L +D+ N I
Sbjct 9 CTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQI 68
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
S+L P+ Q L L L L N++++L F +L L L +N I ++ + F
Sbjct 69 SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINXLRVDAFQDLH 128
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
NL L L N L + GT L +Q + L+ N
Sbjct 129 NLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 162
Score = 54.7 bits (130), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 50/173 (29%), Positives = 81/173 (47%), Gaps = 14/173 (8%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
+T + L N I I +KL +DL +N ++ L A +GL L+ L
Sbjct 34 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA--------FQGLRSLNSL 85
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L N E+P +F+ LF L+++ L N +N L F + +L L+L N + ++ K
Sbjct 86 VLYGNKITELPKSLFEGLFSLQLLLLNANKINXLRVDAFQDLHNLNLLSLYDNKLQTIAK 145
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTP 680
F P R + + + NPF C C + W +++ HTN P +S C +P
Sbjct 146 GTFSP-LRAIQTMHLAQNPFICDCH-LKWLADYL---HTN-PIETSGARCTSP 192
Score = 37.4 bits (85), Expect = 0.41, Method: Compositional matrix adjust.
Identities = 37/131 (28%), Positives = 58/131 (44%), Gaps = 7/131 (5%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
+ L +N I I AFS L +DL N+I EL ++GL ++ + L NK +L
Sbjct 37 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQIS-ELAPDAFQGLRSLNSLVLYGNKITEL 95
Query 472 TRNSF--ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
++ F L L ++ VD+ FQ L NL +L L +N + I L
Sbjct 96 PKSLFEGLFSLQLLLLNANKINXLRVDA----FQDLHNLNLLSLYDNKLQTIAKGTFSPL 151
Query 530 EKLEILDLQHN 540
++ + L N
Sbjct 152 RAIQTMHLAQN 162
>6lbx_A A Repebody (Rb-H2)
Length=275
Score = 73.9 bits (180), Expect = 6e-13, Method: Compositional matrix adjust.
Identities = 60/192 (31%), Positives = 89/192 (46%), Gaps = 12/192 (6%)
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLK 559
S + L NLT L LS N + ++ + + + L L++L L N L L P
Sbjct 80 SALKELTNLTTLILSGNQLQSLPNGVFDKLTNLKVLWLSVNQLQSL--------PDGVFD 131
Query 560 GLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQK 619
L++L L L N +P VF L L ++ L N L +LP VF+ LK L L +
Sbjct 132 KLTNLTSLRLHRNQLQSLPKGVFDKLTNLTVLRLSENQLQSLPEGVFDKLTQLKVLWLGR 191
Query 620 NLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLC-- 677
N + SV VF +L + + NP+DCTC I + WIN+ H+ + S+ +
Sbjct 192 NQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRYLSEWINK-HSGVVRNSAGSVAPD 249
Query 678 NTPPHYHGFPVR 689
+ G PVR
Sbjct 250 SAKCSGSGKPVR 261
Score = 57.8 bits (138), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 60/181 (33%), Positives = 83/181 (46%), Gaps = 5/181 (3%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
A S +K Q LP N+ +L L N+L + A + LT+L + N + L +
Sbjct 49 APHSDIKSVQGIQYLP-NVRLLYLGGNKLHDISA--LKELTNLTTLILSGNQLQSLPNGV 105
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
KL LKVL L N+L L D F TNLT L L N +Q + F K NL L L
Sbjct 106 FDKLTNLKVLWLSVNQLQSLPDGVFDKLTNLTSLRLHRNQLQSLPKGVFDKLTNLTVLRL 165
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
S N L S G +L L+ L L N+++++ D +SL+ + L N P
Sbjct 166 SENQLQSLPEGVFDKLTQLKVLWLGRNQLKSVPDGVFDRL--TSLQYIWLHDNPWDCTCP 223
Query 215 G 215
G
Sbjct 224 G 224
Score = 49.3 bits (116), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 49/140 (35%), Positives = 70/140 (50%), Gaps = 7/140 (5%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L+LS N++Q+L + D N LK L LS NQ++ G F + L L L
Sbjct 84 ELTNLTTLILSGNQLQSLPNGVFDKLTN--LKVLWLSVNQLQSLPDGVFDKLTNLTSLRL 141
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
+ QL SL + + +L N ++ L LS +QL + F K T L +L L N L
Sbjct 142 HRNQLQ-SLPKGVFDKLTNLTV--LRLSENQLQSLPEGVF--DKLTQLKVLWLGRNQLKS 196
Query 289 VGNDSFAWLPQLEYFFLEYN 308
V + F L L+Y +L N
Sbjct 197 VPDGVFDRLTSLQYIWLHDN 216
>2id5_B B Leucine rich repeat neuronal 6A
Length=477
Score = 75.9 bits (185), Expect = 7e-13, Method: Compositional matrix adjust.
Identities = 84/364 (23%), Positives = 151/364 (41%), Gaps = 42/364 (12%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+ C + VP+ +PT +L+L N+++ L F + L L++ N
Sbjct 8 ECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENI 67
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+S +EP L L+ L L+ N L + F +NLT+L + N I + + F
Sbjct 68 VSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDL 127
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE-LS 205
NL +L++ N L L +L++L L + ++ +E L + +L L+
Sbjct 128 YNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLN 187
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
N I+++S RL+ L + + P L T +
Sbjct 188 INAIRDYS------FKRLYRLKVLEISHWP-----------------------YLDTMTP 218
Query 266 TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVR 325
GL NLT L +++ NL V + L L + L YN I + LH L ++
Sbjct 219 NCLYGL---NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQ 275
Query 326 YLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
+ L L ++ ++F+ L L LN+ N + ++ ++F + NL+ L
Sbjct 276 EIQLVG---------GQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLI 326
Query 386 LSNS 389
L ++
Sbjct 327 LDSN 330
Score = 67.8 bits (164), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 90/344 (26%), Positives = 147/344 (43%), Gaps = 62/344 (18%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
T +LDL N + + D FA P LE L N + + + + LFN+R L L+ +
Sbjct 32 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 91
Query 334 TK-----QSISLASLPKID----------DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGL 378
K L++L K+D D+ FQ L L+ L + DND+ I F+GL
Sbjct 92 LKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGL 151
Query 379 INLKYLSLSNSFTSLRTLTNETFVSLAH-SPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
+L+ L+L LT+ +L+H L +L L I+ I +F L L+VL+
Sbjct 152 NSLEQLTLEKC-----NLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE 206
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS 497
+ W L+ +T N L L L +++ + +
Sbjct 207 I-----------SHWPYLDT-------------MTPN------CLYGLNLTSLSITHCNL 236
Query 498 SPSPFQPLRNLT---ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGP 554
+ P+ +R+L L+LS N I+ I ML L +L+ + L LA + +A
Sbjct 237 TAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYA----- 291
Query 555 IYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+GL++L +LN+ N + VF + L+ + L N L
Sbjct 292 ---FRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 332
Score = 53.5 bits (127), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 57/208 (27%), Positives = 83/208 (40%), Gaps = 35/208 (17%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L+L KN+I + D F+ HLE L+L N + + E N+F + + L
Sbjct 35 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIV----SAVEPGAFNNLFNL-----RTL 85
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L N L+P F L NLT LD+S N I + D M + L
Sbjct 86 GLRSNRLKLIPL------------------GVFTGLSNLTKLDISENKIVILLDYMFQDL 127
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
L+ L++ N+L + A GL+ L L LE IP E L L
Sbjct 128 YNLKSLEVGDNDLVYISHRA--------FSGLNSLEQLTLEKCNLTSIPTEALSHLHGLI 179
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNL 617
++ L N+N + F LK L +
Sbjct 180 VLRLRHLNINAIRDYSFKRLYRLKVLEI 207
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 36/121 (30%), Positives = 52/121 (43%), Gaps = 8/121 (7%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+LDL N I +N D LE L+L N + PG L +L L L
Sbjct 36 LLDLGKNRIKTLNQDEFASFPHLEELELNEN----IVSAVEPGA----FNNLFNLRTLGL 87
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN IP+ VF L L +D+ N + L +F + +LKSL + N + + +
Sbjct 88 RSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRA 147
Query 630 F 630
F
Sbjct 148 F 148
Score = 36.2 bits (82), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 29/109 (27%), Positives = 51/109 (47%), Gaps = 0/109 (0%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+T L++TH L +P L L++ +N IS +E + +L L+ + L +L
Sbjct 225 NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQL 284
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+ + F L L++ N + ++ + F NL TL L N L+
Sbjct 285 AVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLA 333
Score = 34.3 bits (77), Expect = 6.9, Method: Compositional matrix adjust.
Identities = 21/59 (36%), Positives = 33/59 (56%), Gaps = 1/59 (2%)
Query 587 ELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
E +++DLG N + TL F + L+ L L +N++++VE F F NL L +R N
Sbjct 33 ETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLF-NLRTLGLRSN 90
>4oqt_A A Leucine-rich repeat and immunoglobulin-like domain-containing
nogo receptor-interacting protein 1
Length=478
Score = 75.9 bits (185), Expect = 8e-13, Method: Compositional matrix adjust.
Identities = 84/364 (23%), Positives = 151/364 (41%), Gaps = 42/364 (12%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+ C + VP+ +PT +L+L N+++ L F + L L++ N
Sbjct 8 ECSAQDRAVLCHRKRFVAVPEGIPTETRLLDLGKNRIKTLNQDEFASFPHLEELELNENI 67
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+S +EP L L+ L L+ N L + F +NLT+L + N I + + F
Sbjct 68 VSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDL 127
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE-LS 205
NL +L++ N L L +L++L L + ++ +E L + +L L+
Sbjct 128 YNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLN 187
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
N I+++S RL+ L + + P L T +
Sbjct 188 INAIRDYS------FKRLYRLKVLEISHWP-----------------------YLDTMTP 218
Query 266 TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVR 325
GL NLT L +++ NL V + L L + L YN I + LH L ++
Sbjct 219 NCLYGL---NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQ 275
Query 326 YLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
+ L L ++ ++F+ L L LN+ N + ++ ++F + NL+ L
Sbjct 276 EIQLVG---------GQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLI 326
Query 386 LSNS 389
L ++
Sbjct 327 LDSN 330
Score = 67.8 bits (164), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 90/344 (26%), Positives = 147/344 (43%), Gaps = 62/344 (18%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
T +LDL N + + D FA P LE L N + + + + LFN+R L L+ +
Sbjct 32 TETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNR 91
Query 334 TK-----QSISLASLPKID----------DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGL 378
K L++L K+D D+ FQ L L+ L + DND+ I F+GL
Sbjct 92 LKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGL 151
Query 379 INLKYLSLSNSFTSLRTLTNETFVSLAH-SPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
+L+ L+L LT+ +L+H L +L L I+ I +F L L+VL+
Sbjct 152 NSLEQLTLEKC-----NLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLE 206
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS 497
+ W L+ +T N L L L +++ + +
Sbjct 207 I-----------SHWPYLDT-------------MTPN------CLYGLNLTSLSITHCNL 236
Query 498 SPSPFQPLRNLT---ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGP 554
+ P+ +R+L L+LS N I+ I ML L +L+ + L LA + +A
Sbjct 237 TAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYA----- 291
Query 555 IYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+GL++L +LN+ N + VF + L+ + L N L
Sbjct 292 ---FRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 332
Score = 53.5 bits (127), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 57/208 (27%), Positives = 83/208 (40%), Gaps = 35/208 (17%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L+L KN+I + D F+ HLE L+L N + + E N+F + + L
Sbjct 35 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIV----SAVEPGAFNNLFNL-----RTL 85
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L N L+P F L NLT LD+S N I + D M + L
Sbjct 86 GLRSNRLKLIPL------------------GVFTGLSNLTKLDISENKIVILLDYMFQDL 127
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
L+ L++ N+L + A GL+ L L LE IP E L L
Sbjct 128 YNLKSLEVGDNDLVYISHRA--------FSGLNSLEQLTLEKCNLTSIPTEALSHLHGLI 179
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNL 617
++ L N+N + F LK L +
Sbjct 180 VLRLRHLNINAIRDYSFKRLYRLKVLEI 207
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 36/121 (30%), Positives = 52/121 (43%), Gaps = 8/121 (7%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+LDL N I +N D LE L+L N + PG L +L L L
Sbjct 36 LLDLGKNRIKTLNQDEFASFPHLEELELNEN----IVSAVEPGA----FNNLFNLRTLGL 87
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN IP+ VF L L +D+ N + L +F + +LKSL + N + + +
Sbjct 88 RSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRA 147
Query 630 F 630
F
Sbjct 148 F 148
Score = 35.8 bits (81), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 29/109 (27%), Positives = 51/109 (47%), Gaps = 0/109 (0%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+T L++TH L +P L L++ +N IS +E + +L L+ + L +L
Sbjct 225 NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQL 284
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+ + F L L++ N + ++ + F NL TL L N L+
Sbjct 285 AVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLA 333
Score = 34.3 bits (77), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 21/59 (36%), Positives = 33/59 (56%), Gaps = 1/59 (2%)
Query 587 ELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
E +++DLG N + TL F + L+ L L +N++++VE F F NL L +R N
Sbjct 33 ETRLLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLF-NLRTLGLRSN 90
>2v9t_B B SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Length=220
Score = 72.4 bits (176), Expect = 9e-13, Method: Compositional matrix adjust.
Identities = 50/154 (32%), Positives = 78/154 (51%), Gaps = 0/154 (0%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
CT S+ + DC LT++P +LP IT + L N ++ +P F+ Y +L +D+ N I
Sbjct 9 CTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQI 68
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
S+L P+ Q L L L L N++++L F +L L L +N I ++ + F
Sbjct 69 SELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLH 128
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
NL L L N L + GT L +Q + L+ N
Sbjct 129 NLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQN 162
Score = 54.7 bits (130), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 50/173 (29%), Positives = 81/173 (47%), Gaps = 14/173 (8%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
+T + L N I I +KL +DL +N ++ L A +GL L+ L
Sbjct 34 ITEIRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQISELAPDA--------FQGLRSLNSL 85
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L N E+P +F+ LF L+++ L N +N L F + +L L+L N + ++ K
Sbjct 86 VLYGNKITELPKSLFEGLFSLQLLLLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAK 145
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTP 680
F P R + + + NPF C C + W +++ HTN P +S C +P
Sbjct 146 GTFSP-LRAIQTMHLAQNPFICDCH-LKWLADYL---HTN-PIETSGARCTSP 192
Score = 37.7 bits (86), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 37/131 (28%), Positives = 58/131 (44%), Gaps = 7/131 (5%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
+ L +N I I AFS L +DL N+I EL ++GL ++ + L NK +L
Sbjct 37 IRLEQNTIKVIPPGAFSPYKKLRRIDLSNNQIS-ELAPDAFQGLRSLNSLVLYGNKITEL 95
Query 472 TRNSF--ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
++ F L L ++ VD+ FQ L NL +L L +N + I L
Sbjct 96 PKSLFEGLFSLQLLLLNANKINCLRVDA----FQDLHNLNLLSLYDNKLQTIAKGTFSPL 151
Query 530 EKLEILDLQHN 540
++ + L N
Sbjct 152 RAIQTMHLAQN 162
>5z15_B B Toll-like receptor 8
Length=811
Score = 76.3 bits (186), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 191/805 (24%), Positives = 303/805 (38%), Gaps = 192/805 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPXXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
+ DDF L L +N+ N I I +F NL+ + LS + S L +T
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRIS--PLVKDTX 416
Query 402 VSL---------------------AHS-------PL---------HILNLTKNKISKIES 424
HS PL L+L+ N I I
Sbjct 417 XXXXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGP 476
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ F L + L+L N Q L+G E+ + ++ KYL LT N +
Sbjct 477 NQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASAL 528
Query 485 LMLRRVALKNVDSSPSPF------------QPLRNLTILDLSNNNIANINDDM-LEGLEK 531
L + + ++ + F Q NL +L+LS+NNI + D LE
Sbjct 529 TELSDLEVLDLSYNSHYFXXXGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSL 588
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFE 587
+E++ N L LW + + I KGL +L L+L N IP E F L E
Sbjct 589 VELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTE 646
Query 588 LKIID---------------------------------------------LGLNNLNTLP 602
L I D L N ++ LP
Sbjct 647 LHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLP 706
Query 603 ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNWI 661
+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W+
Sbjct 707 SGFLSEVSSLKHLDLSSNLLKTINKSALXXXXXTKLSMLELHGNPFECTCD-IGDFRRWM 765
Query 662 NE-THTNIPELSSHYLCNTPPHYHG 685
+E + IP L +C +P G
Sbjct 766 DEHLNVKIPRLVD-VICASPGDQRG 789
>3wpe_A A Toll-like receptor 9
Length=801
Score = 75.9 bits (185), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 92/337 (27%), Positives = 139/337 (41%), Gaps = 36/337 (11%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L++ N++ I+ MFT L L+ L LS++ S + + FV L + L +L+L+ NK+
Sbjct 455 LDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSIS-QAVNGSQFVPL--TSLRVLDLSHNKL 511
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALV 479
+F+ L LE LDL N + G G F L +YL L N +
Sbjct 512 DLYHGRSFTELPQLEALDLSYNSQPFSMQGV---GHNLSFVAQLPSLRYLSLAHNG---I 565
Query 480 PSLQRLMLRRVALKNVDSSPSP--------------FQPLRNLTILDLSNNNIANINDDM 525
S L +L+ +D S + F+ LRNL LDLS N++ +
Sbjct 566 HSRVSQKLSSASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLDLSENHLHTLLPRH 625
Query 526 LEGLEK-LEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFK 583
L+ L K L L L+ NNLA W L L L L+L N +
Sbjct 626 LDNLPKSLRQLRLRDNNLAFFNWSS---------LTVLPRLEALDLAGNQLKALSNGSLP 676
Query 584 DLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMR 643
L+ +D+ N++ + F L LNL N + +V+ FG L LD+
Sbjct 677 PGIRLQKLDVSSNSIGFVIPGFFVRATRLIELNLSANALKTVDPSWFGXXAGTLKILDVS 736
Query 644 FNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTP 680
NP C FV+++ E +P C +P
Sbjct 737 ANPLHCA--XXXAFVDFLLERQEAVPXXXXXVTCGSP 771
Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 70/249 (28%), Positives = 112/249 (45%), Gaps = 28/249 (11%)
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLMSNSIQK 137
+LD+ N + ++ E+ +L L+ L L HN +SQ ++ F T+L L L N +
Sbjct 454 TLDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSISQAVNGSQFVPLTSLRVLDLSHNKLDL 513
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQ------VQLENLQELLLSNNKIQALKSEEL 191
F + L LDLS+N + G QL +L+ L L++N I + S++L
Sbjct 514 YHGRSFTELPQLEALDLSYNSQPFSMQGVGHNLSFVAQLPSLRYLSLAHNGIHSRVSQKL 573
Query 192 DIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL----NNVQLGPSLTEKLCLELAN 247
+++SL+ L+ S N + + A G L+ F N VQL L+E L
Sbjct 574 ---SSASLRALDFSGNSLSQ-----MWAEGDLYLCFFKGLRNLVQL--DLSENHLHTLLP 623
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTM------LDLSYNNLNVVGNDSFAWLPQLE 301
+ NL S QL N W++LT+ LDL+ N L + N S +L+
Sbjct 624 RHLDNLPKSLRQLRLRDNNLAF-FNWSSLTVLPRLEALDLAGNQLKALSNGSLPPGIRLQ 682
Query 302 YFFLEYNNI 310
+ N+I
Sbjct 683 KLDVSSNSI 691
Score = 52.8 bits (125), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 71/264 (27%), Positives = 123/264 (47%), Gaps = 32/264 (12%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP----------ELCQKLPM 100
T++ VL+L+HN+L +FT QL +LD+ +N+ +P +LP
Sbjct 499 TSLRVLDLSHNKLDLYHGRSFTELPQLEALDLSYNS----QPFSMQGVGHNLSFVAQLPS 554
Query 101 LKVLNLQHNEL-SQLSDKTFAFCTNLTELHLMSNSIQKIKNNP------FVKQKNLITLD 153
L+ L+L HN + S++S K + +L L NS+ ++ F +NL+ LD
Sbjct 555 LRYLSLAHNGIHSRVSQKLSS--ASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLD 612
Query 154 LSHNGLSSTKLGTQVQ--LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
LS N L T L + ++L++L L +N + L + L+ L+L+ NQ+K
Sbjct 613 LSENHL-HTLLPRHLDNLPKSLRQLRLRDNNLAFFNWSSLTVLPR--LEALDLAGNQLKA 669
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
S G RL L +++ +G + + T + L+LS + L T + ++ G
Sbjct 670 LSNGSLPPGIRLQKLDVSSNSIGFVIPGFF---VRATRLIELNLSANALKTV-DPSWFGX 725
Query 272 KWTNLTMLDLSYNNLNVVGNDSFA 295
L +LD+S N L+ +F
Sbjct 726 XAGTLKILDVSANPLHCAXXXAFV 749
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 115/422 (27%), Positives = 167/422 (40%), Gaps = 81/422 (19%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHN----GLSSTKLGTQVQLE------- 171
N+T L L+SN I + ++ FV NL L+L N GLS ++ +E
Sbjct 42 ANVTSLSLISNRIHHLHDSDFVHLSNLRVLNLKWNCPPAGLSPMHFPCRMTIEPNTFLAV 101
Query 172 -NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L+EL LS N I + + SSL L LS I P F + L L+++
Sbjct 102 PTLEELNLSYNGITTVPALP------SSLVSLSLSHTSILVLGPTHFTGLHALRFLYMDG 155
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
C + N R L ++ L LGL NLT L L YNNL V
Sbjct 156 N----------CYYM-NPCPRALEVAPGAL--------LGLG--NLTHLSLKYNNLTEVP 194
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL-------ASL 343
P L+ L YN+I L L L +R L++ + + + +
Sbjct 195 R---RLPPSLDTLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCRECPKNF 251
Query 344 PKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS 403
PK+ +F L LE L ++D+ + ++ + F GL L+ L LS +F F
Sbjct 252 PKLHPDTFSHLSRLEGLVLKDSSLYKLEKDWFRGLGRLQVLDLSENFLYDYITKTTIFND 311
Query 404 LAHSPLHILNLTKNKISKIE------SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN 457
L L LNL+ N K+ + +F L LE LD + G +R L N
Sbjct 312 LTQ--LRRLNLSFNYHKKVSFAHLHLASSFGSLVSLEKLD---------MHGIFFRSLTN 360
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
I T S +P LQ L L+ + S F +L +DLS+N
Sbjct 361 I-------------TLQSLTRLPKLQSLHLQLNFINQAQL--SIFGAFPSLLFVDLSDNR 405
Query 518 IA 519
I+
Sbjct 406 IS 407
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 85/284 (30%), Positives = 121/284 (43%), Gaps = 34/284 (12%)
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
+ ++ L LS++ +S N + + T+L +LDLS+N L++ SF LPQLE L Y
Sbjct 474 SRLQCLRLSHNSISQAVNGSQF-VPLTSLRVLDLSHNKLDLYHGRSFTELPQLEALDLSY 532
Query 308 NNIQHLFSHSLHGLF------NVRYLNLK----RSFTKQSISLASLPKID----DFSFQW 353
N+ H L ++RYL+L S Q +S ASL +D S W
Sbjct 533 NSQPFSMQGVGHNLSFVAQLPSLRYLSLAHNGIHSRVSQKLSSASLRALDFSGNSLSQMW 592
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
+ +L F GL NL L LS + L TL +L S L L
Sbjct 593 AEGDLYL------------CFFKGLRNLVQLDLSEN--HLHTLLPRHLDNLPKS-LRQLR 637
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
L N ++ + + L LE LDL N++ G G+ + ++ +S N +
Sbjct 638 LRDNNLAFFNWSSLTVLPRLEALDLAGNQLKALSNGSLPPGIR-LQKLDVSSNSIGFVIP 696
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRN-LTILDLSNN 516
F L L L ALK VD PS F L ILD+S N
Sbjct 697 GFFVRATRLIELNLSANALKTVD--PSWFGXXAGTLKILDVSAN 738
Score = 40.8 bits (94), Expect = 0.079, Method: Compositional matrix adjust.
Identities = 153/685 (22%), Positives = 248/685 (36%), Gaps = 158/685 (23%)
Query 32 HEVADCSHLKLTQVP---DDLP-TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
H DC+ L L VP P N+T L+L N++ L ++F S L
Sbjct 19 HGQVDCNWLFLKSVPHFSAGAPRANVTSLSLISNRIHHLHDSDFVHLSNL---------- 68
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFC--TNLTELHLMSNSIQKIKNNPFVK 145
+VLNL+ N C L+ +H I+ N F+
Sbjct 69 --------------RVLNLKWN------------CPPAGLSPMHFPCR--MTIEPNTFLA 100
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQE----LLLSNNKIQALKSEELDIFANSSLKK 201
L L+LS+NG+++ + L+L L + ++ + +
Sbjct 101 VPTLEELNLSYNGITTVPALPSSLVSLSLSHTSILVLGPTHFTGLHALRF-LYMDGNCYY 159
Query 202 LELSSNQIKEFSPGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
+ + E +PG +G L L L NN+ P S+ L LS +
Sbjct 160 MNPCPRAL-EVAPGALLGLGNLTHLSLKYNNLTEVPRRLPP--------SLDTLLLSYNH 210
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYN----------------NLNVVGNDSFAWLPQLEYF 303
+ T + L T L +LD+ N N + D+F+ L +LE
Sbjct 211 IVTLAPEDLANL--TALRVLDVGGNCRRCDHARNPCRECPKNFPKLHPDTFSHLSRLEGL 268
Query 304 FLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNME 363
L+ +++ L GL ++ L+L +F I+ ++ F L L LN+
Sbjct 269 VLKDSSLYKLEKDWFRGLGRLQVLDLSENFLYDYITKTTI-------FNDLTQLRRLNLS 321
Query 364 DNDIPGIK------SNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILNLTK 416
N + ++ F L++L+ L + F R+LTN T SL P L L+L
Sbjct 322 FNYHKKVSFAHLHLASSFGSLVSLEKLDMHGIF--FRSLTNITLQSLTRLPKLQSLHLQL 379
Query 417 NKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENI------------------ 458
N I++ + F L +DL N I
Sbjct 380 NFINQAQLSIFGAFPSLLFVDLSDNRISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 439
Query 459 -------------FEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPL 505
F + LS N + + + F + LQ L L ++ + S F PL
Sbjct 440 XXXXXXXXSCNLNFTLDLSRNNLVTIQQEMFTRLSRLQCLRLSHNSISQAVNG-SQFVPL 498
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
+L +LDLS+N + + L +LE LDL +N ++ + G + F+ L L
Sbjct 499 TSLRVLDLSHNKLDLYHGRSFTELPQLEALDLSYN--SQPFSMQGVGHNLSFVAQLPSLR 556
Query 566 ILNLESNGF-----------------------------DEIPVEVFKDLFELKIIDLGLN 596
L+L NG ++ + FK L L +DL N
Sbjct 557 YLSLAHNGIHSRVSQKLSSASLRALDFSGNSLSQMWAEGDLYLCFFKGLRNLVQLDLSEN 616
Query 597 NLNT-LPASVFNNQVSLKSLNLQKN 620
+L+T LP + N SL+ L L+ N
Sbjct 617 HLHTLLPRHLDNLPKSLRQLRLRDN 641
Score = 36.2 bits (82), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 35/116 (30%), Positives = 50/116 (43%), Gaps = 24/116 (21%)
Query 47 DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNL 106
D+LP ++ L L N L F +S LT LP L+ L+L
Sbjct 627 DNLPKSLRQLRLRDNNLA------FFNWSSLTV------------------LPRLEALDL 662
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSST 162
N+L LS+ + L +L + SNSI + FV+ LI L+LS N L +
Sbjct 663 AGNQLKALSNGSLPPGIRLQKLDVSSNSIGFVIPGFFVRATRLIELNLSANALKTV 718
>6zjz_B B Toll-like receptor 8
Length=801
Score = 75.9 bits (185), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 191/818 (23%), Positives = 304/818 (37%), Gaps = 196/818 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGXXXLTKINLNHNPNXXXXXX 79
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 80 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 136
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 137 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 195
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 196 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 243
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 244 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 301
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 302 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 356
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 357 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 414
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 415 XXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 470
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 471 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 522
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 523 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 582
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 583 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 640
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 641 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 700
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 701 LPSGFLSEVSSLKHLDLSSNLLKTINKSALXXXXXXKLSMLELHGNPFECTCD-IGDFRR 759
Query 660 WINE-THTNIPELSSHYLCNTPPHYHGFPVRLFDTSSC 696
W++E + IP L +C +P G + + ++C
Sbjct 760 WMDEHLNVKIPRLVD-VICASPGDQRGKSIVSLELTTC 796
>3wn4_A A Toll-like receptor 8
Length=811
Score = 75.5 bits (184), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>3kj4_F D Reticulon-4 receptor
Length=286
Score = 72.4 bits (176), Expect = 2e-12, Method: Composition-based stats.
Identities = 60/161 (37%), Positives = 80/161 (50%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 32 SSQRIFLHGNRISYVPAAS--FQSCRNLTILWLHSNALAGIDAAAFTGLTLLEQLDLSDN 89
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
R+ P F +GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 90 AQLRVVD------PTTF-RGLGHLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNNLQA 142
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 143 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 179
Score = 68.2 bits (165), Expect = 6e-11, Method: Composition-based stats.
Identities = 60/191 (31%), Positives = 94/191 (49%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + GI + FTGL L+ L LS++ LR + TF L H L
Sbjct 50 SFQSCRNLTILWLHSNALAGIDAAAFTGLTLLEQLDLSDN-AQLRVVDPTTFRGLGH--L 106
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 107 HTLHLDRCGLQELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 165
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 166 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLVPL 223
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 224 RSLQYLRLNDN 234
Score = 63.5 bits (153), Expect = 2e-09, Method: Composition-based stats.
Identities = 57/203 (28%), Positives = 89/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N ++ ++
Sbjct 17 CPQQGLQAVPTGIPASSQRIFLHGNRISYVPAASFQSCRNLTILWLHSNALAGIDAAAFT 76
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL +Q++ F L L L
Sbjct 77 GLTLLEQLDLSDNAQLRVVDPTTFRGLGHLHTLHLDRCGLQELGPGLFRGLAALQYLYLQ 136
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 137 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFR--GLHSLDRLLLHQNHVARVHPH 194
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 195 AFRDLGRLMTLYLFANNLSMLPA 217
Score = 62.8 bits (151), Expect = 4e-09, Method: Composition-based stats.
Identities = 67/231 (29%), Positives = 103/231 (45%), Gaps = 26/231 (11%)
Query 367 IPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDA 426
IP +F + Y+ + SF S R LT IL L N ++ I++ A
Sbjct 29 IPASSQRIFLHGNRISYVPAA-SFQSCRNLT-------------ILWLHSNALAGIDAAA 74
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLM 486
F+ L LE LDL N + + +RGL ++ ++L +L F + +LQ L
Sbjct 75 FTGLTLLEQLDLSDNAQLRVVDPTTFRGLGHLHTLHLDRCGLQELGPGLFRGLAALQYLY 134
Query 487 LRRVALKNVDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
L+ N+ + P + F+ L NLT L L N I ++ + GL L+ L L N++AR+
Sbjct 135 LQD---NNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARV 191
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
HA + L L L L +N +P EV L L+ + L N
Sbjct 192 HPHA--------FRDLGRLMTLYLFANNLSMLPAEVLVPLRSLQYLRLNDN 234
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 48/153 (31%), Positives = 66/153 (43%), Gaps = 3/153 (2%)
Query 56 LNLTHN-QLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
L+L+ N QLR + F L +L + + +L P L + L L+ L LQ N L L
Sbjct 84 LDLSDNAQLRVVDPTTFRGLGHLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNNLQAL 143
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
D TF NLT L L N I + + F +L L L N ++ L L
Sbjct 144 PDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHAFRDLGRLM 203
Query 175 ELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
L L N + L +E L SL+ L L+ N
Sbjct 204 TLYLFANNLSMLPAEVL--VPLRSLQYLRLNDN 234
Score = 46.2 bits (108), Expect = 8e-04, Method: Composition-based stats.
Identities = 50/171 (29%), Positives = 75/171 (44%), Gaps = 16/171 (9%)
Query 248 TSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
T + L LS N+QL TTF GL +L L L L +G F L L+Y +L+
Sbjct 79 TLLEQLDLSDNAQLRVVDPTTFRGLG--HLHTLHLDRCGLQELGPGLFRGLAALQYLYLQ 136
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L + N
Sbjct 137 DNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLLHQNH 187
Query 367 IPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ + + F L L L L + +L L E V L L L L N
Sbjct 188 VARVHPHAFRDLGRLMTLYLFAN--NLSMLPAEVLVPL--RSLQYLRLNDN 234
>3kj4_C A Reticulon-4 receptor
Length=286
Score = 72.4 bits (176), Expect = 2e-12, Method: Composition-based stats.
Identities = 60/161 (37%), Positives = 80/161 (50%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 32 SSQRIFLHGNRISYVPAAS--FQSCRNLTILWLHSNALAGIDAAAFTGLTLLEQLDLSDN 89
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
R+ P F +GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 90 AQLRVVD------PTTF-RGLGHLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNNLQA 142
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 143 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 179
Score = 68.2 bits (165), Expect = 6e-11, Method: Composition-based stats.
Identities = 60/191 (31%), Positives = 94/191 (49%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + GI + FTGL L+ L LS++ LR + TF L H L
Sbjct 50 SFQSCRNLTILWLHSNALAGIDAAAFTGLTLLEQLDLSDN-AQLRVVDPTTFRGLGH--L 106
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 107 HTLHLDRCGLQELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 165
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 166 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLVPL 223
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 224 RSLQYLRLNDN 234
Score = 63.5 bits (153), Expect = 2e-09, Method: Composition-based stats.
Identities = 57/203 (28%), Positives = 89/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N ++ ++
Sbjct 17 CPQQGLQAVPTGIPASSQRIFLHGNRISYVPAASFQSCRNLTILWLHSNALAGIDAAAFT 76
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL +Q++ F L L L
Sbjct 77 GLTLLEQLDLSDNAQLRVVDPTTFRGLGHLHTLHLDRCGLQELGPGLFRGLAALQYLYLQ 136
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 137 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFR--GLHSLDRLLLHQNHVARVHPH 194
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 195 AFRDLGRLMTLYLFANNLSMLPA 217
Score = 62.8 bits (151), Expect = 4e-09, Method: Composition-based stats.
Identities = 67/231 (29%), Positives = 103/231 (45%), Gaps = 26/231 (11%)
Query 367 IPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDA 426
IP +F + Y+ + SF S R LT IL L N ++ I++ A
Sbjct 29 IPASSQRIFLHGNRISYVPAA-SFQSCRNLT-------------ILWLHSNALAGIDAAA 74
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLM 486
F+ L LE LDL N + + +RGL ++ ++L +L F + +LQ L
Sbjct 75 FTGLTLLEQLDLSDNAQLRVVDPTTFRGLGHLHTLHLDRCGLQELGPGLFRGLAALQYLY 134
Query 487 LRRVALKNVDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL 545
L+ N+ + P + F+ L NLT L L N I ++ + GL L+ L L N++AR+
Sbjct 135 LQD---NNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARV 191
Query 546 WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
HA + L L L L +N +P EV L L+ + L N
Sbjct 192 HPHA--------FRDLGRLMTLYLFANNLSMLPAEVLVPLRSLQYLRLNDN 234
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 48/153 (31%), Positives = 66/153 (43%), Gaps = 3/153 (2%)
Query 56 LNLTHN-QLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
L+L+ N QLR + F L +L + + +L P L + L L+ L LQ N L L
Sbjct 84 LDLSDNAQLRVVDPTTFRGLGHLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNNLQAL 143
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
D TF NLT L L N I + + F +L L L N ++ L L
Sbjct 144 PDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHAFRDLGRLM 203
Query 175 ELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
L L N + L +E L SL+ L L+ N
Sbjct 204 TLYLFANNLSMLPAEVL--VPLRSLQYLRLNDN 234
Score = 46.2 bits (108), Expect = 8e-04, Method: Composition-based stats.
Identities = 50/171 (29%), Positives = 75/171 (44%), Gaps = 16/171 (9%)
Query 248 TSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
T + L LS N+QL TTF GL +L L L L +G F L L+Y +L+
Sbjct 79 TLLEQLDLSDNAQLRVVDPTTFRGLG--HLHTLHLDRCGLQELGPGLFRGLAALQYLYLQ 136
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L + N
Sbjct 137 DNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLLHQNH 187
Query 367 IPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ + + F L L L L + +L L E V L L L L N
Sbjct 188 VARVHPHAFRDLGRLMTLYLFAN--NLSMLPAEVLVPL--RSLQYLRLNDN 234
>3w3k_B B Toll-like receptor 8
Length=811
Score = 75.1 bits (183), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>3w3k_A A Toll-like receptor 8
Length=811
Score = 75.1 bits (183), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4ufr_C C LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=484
Score = 74.3 bits (181), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 26 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 73
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 74 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 125
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 126 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 185
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 186 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 219
Score = 70.1 bits (170), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 64 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 114
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 115 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 172
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 173 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 228
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 229 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 286
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 287 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 336
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 337 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 390
Score = 66.2 bits (160), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 22 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 81
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 82 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 141
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 142 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 198
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 199 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 251
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 252 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 302
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 303 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 361
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 362 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 396
Score = 61.6 bits (148), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 43 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 102
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 103 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 156
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 157 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 214
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 215 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 264
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 265 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 317
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 318 TVCNQLPNLQVLDLSYNLL-EDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 374
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 375 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 422
>5awc_B B Toll-like receptor 8
Length=811
Score = 75.1 bits (183), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALXXXXXTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>5awd_A A Toll-like receptor 8
Length=811
Score = 75.1 bits (183), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4ufr_A A LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=484
Score = 74.3 bits (181), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 26 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 73
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 74 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 125
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 126 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 185
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 186 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 219
Score = 70.1 bits (170), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 64 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 114
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 115 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 172
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 173 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 228
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 229 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 286
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 287 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 336
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 337 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 390
Score = 66.2 bits (160), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 22 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 81
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 82 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 141
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 142 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 198
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 199 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 251
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 252 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 302
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 303 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 361
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 362 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 396
Score = 61.6 bits (148), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 43 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 102
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 103 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 156
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 157 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 214
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 215 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 264
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 265 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 317
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 318 TVCNQLPNLQVLDLSYNLL-EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 374
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 375 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 422
>4r09_A A Toll-like receptor 8
Length=811
Score = 75.1 bits (183), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>3w3j_B B Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 2e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4bst_B B LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=539
Score = 74.3 bits (181), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 47 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 94
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 95 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 146
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 147 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 206
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 207 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 240
Score = 70.1 bits (170), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 85 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 135
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 136 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 193
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 194 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 249
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 250 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 307
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 308 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 357
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 358 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 411
Score = 66.2 bits (160), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 43 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 102
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 103 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 162
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 163 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 219
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 220 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 272
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 273 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 323
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 324 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 382
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 383 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 417
Score = 61.6 bits (148), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 64 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 123
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 124 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 177
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 178 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 235
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 236 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 285
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 286 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 338
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 339 TVCNQLPNLQVLDLSYNLL-EDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 395
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 396 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 443
>6wml_A A Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 299/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLXDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLXXVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4r08_D D Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>5az5_D D Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4bss_B B LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=539
Score = 74.3 bits (181), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 47 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 94
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 95 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 146
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 147 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 206
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 207 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 240
Score = 69.7 bits (169), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 85 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 135
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 136 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 193
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 194 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 249
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 250 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 307
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 308 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 357
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 358 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 411
Score = 66.2 bits (160), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 43 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 102
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 103 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 162
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 163 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 219
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 220 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 272
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 273 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 323
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 324 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 382
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 383 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 417
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 64 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 123
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 124 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 177
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 178 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 235
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 236 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 285
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 286 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 338
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 339 TVCNQLPNLQVLDLSYNLL-EDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 395
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 396 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 443
>5awc_A A Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4r09_C C Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>5awb_A A Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4qbz_A A Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4kng_A A Leucine-rich repeat-containing G-protein coupled receptor
5
Length=531
Score = 74.3 bits (181), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 25 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 72
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 73 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 124
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 125 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 184
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 185 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 218
Score = 69.7 bits (169), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 63 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 113
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 114 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 171
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 172 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 227
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 228 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 285
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 286 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 335
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 336 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 389
Score = 66.2 bits (160), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 167/395 (42%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 21 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 80
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 81 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 140
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 141 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 197
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 198 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 250
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 251 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 301
Query 330 KRSFTKQSISLASLPKI-------------------DDFSFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ D SF + L+ +++ N+I I
Sbjct 302 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 360
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 361 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 395
Score = 61.6 bits (148), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 42 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 101
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 102 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 155
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 156 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 213
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 214 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 263
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 264 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 316
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 317 TVCNQLPNLQVLDLSYNLL-EDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 373
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 374 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 421
>4bst_A A LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=539
Score = 74.3 bits (181), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 47 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 94
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 95 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 146
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 147 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 206
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 207 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 240
Score = 69.7 bits (169), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 85 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 135
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 136 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 193
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 194 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 249
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 250 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 307
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 308 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 357
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 358 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 411
Score = 66.2 bits (160), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 43 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 102
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 103 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 162
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 163 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 219
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 220 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 272
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 273 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 323
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 324 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 382
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 383 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 417
Score = 61.6 bits (148), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 64 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 123
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 124 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 177
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 178 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 235
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 236 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 285
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 286 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 338
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 339 TVCNQLPNLQVLDLSYNLL-EDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 395
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 396 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 443
>4r08_A A Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALEXXXXXKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4ufs_A A LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=484
Score = 73.9 bits (180), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 26 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 73
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 74 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 125
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 126 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 185
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 186 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 219
Score = 69.7 bits (169), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 64 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 114
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 115 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 172
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 173 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 228
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 229 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 286
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 287 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 336
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 337 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 390
Score = 65.9 bits (159), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 22 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 81
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 82 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 141
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 142 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 198
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 199 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 251
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 252 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 302
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 303 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 361
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 362 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 396
Score = 61.2 bits (147), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 43 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 102
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 103 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 156
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 157 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 214
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 215 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 264
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 265 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 317
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 318 TVCNQLPNLQVLDLSYNLL-EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 374
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 375 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 422
>3w3l_A A Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>3w3l_D D Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>6wml_B B Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>3w3l_B B Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>3w3m_A A Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>3w3l_C C Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>3w3n_A A Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4bsu_F F LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=539
Score = 74.3 bits (181), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 47 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 94
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 95 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 146
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 147 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 206
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 207 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 240
Score = 69.7 bits (169), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 85 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 135
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 136 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 193
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 194 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 249
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 250 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 307
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 308 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 357
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 358 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 411
Score = 66.2 bits (160), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 43 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 102
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 103 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 162
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 163 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 219
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 220 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 272
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 273 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 323
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 324 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 382
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 383 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 417
Score = 61.2 bits (147), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 64 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 123
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 124 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 177
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 178 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 235
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 236 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 285
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 286 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 338
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 339 TVCNQLPNLQVLDLSYNLL-EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 395
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 396 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 443
>4bsu_E E LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=539
Score = 73.9 bits (180), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 47 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 94
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 95 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 146
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 147 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 206
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 207 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 240
Score = 70.1 bits (170), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 85 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 135
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 136 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 193
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 194 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 249
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 250 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 307
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 308 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 357
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 358 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 411
Score = 66.2 bits (160), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 43 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 102
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 103 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 162
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 163 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 219
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 220 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 272
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 273 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 323
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 324 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 382
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 383 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 417
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 64 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 123
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 124 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 177
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 178 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 235
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 236 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 285
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 286 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 338
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 339 TVCNQLPNLQVLDLSYNLL-EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 395
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 396 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 443
>4bsu_A A LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=539
Score = 73.9 bits (180), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 47 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 94
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 95 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 146
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 147 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 206
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 207 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 240
Score = 69.7 bits (169), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 85 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 135
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 136 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 193
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 194 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 249
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 250 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 307
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 308 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 357
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 358 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 411
Score = 66.6 bits (161), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 43 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 102
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 103 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 162
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 163 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 219
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 220 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 272
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 273 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 323
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 324 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 382
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 383 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 417
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 64 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 123
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 124 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 177
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 178 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 235
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 236 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 285
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 286 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 338
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 339 TVCNQLPNLQVLDLSYNLL-EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 395
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 396 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 443
>4bss_A A LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=539
Score = 73.9 bits (180), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 47 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 94
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 95 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 146
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 147 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 206
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 207 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 240
Score = 70.1 bits (170), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 85 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 135
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 136 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 193
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 194 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 249
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 250 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 307
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 308 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 357
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 358 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 411
Score = 66.6 bits (161), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 43 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 102
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 103 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 162
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 163 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 219
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 220 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 272
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 273 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 323
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 324 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 382
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 383 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 417
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 64 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 123
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 124 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 177
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 178 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 235
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 236 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 285
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 286 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 338
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 339 TVCNQLPNLQVLDLSYNLL-EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 395
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 396 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 443
>4bss_F F LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=539
Score = 73.9 bits (180), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 47 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 94
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 95 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 146
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 147 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 206
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 207 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 240
Score = 69.7 bits (169), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 85 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 135
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 136 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 193
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 194 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 249
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 250 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 307
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 308 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 357
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 358 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 411
Score = 65.9 bits (159), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 43 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 102
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 103 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 162
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 163 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 219
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 220 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 272
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 273 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 323
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 324 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 382
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 383 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 417
Score = 61.2 bits (147), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 64 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 123
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 124 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 177
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 178 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 235
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 236 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 285
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 286 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 338
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 339 TVCNQLPNLQVLDLSYNLL-EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 395
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 396 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 443
>4bss_E E LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=539
Score = 73.9 bits (180), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 47 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 94
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 95 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 146
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 147 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 206
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 207 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 240
Score = 70.1 bits (170), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 85 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 135
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 136 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 193
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 194 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 249
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 250 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 307
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 308 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 357
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 358 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 411
Score = 66.2 bits (160), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 43 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 102
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 103 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 162
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 163 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 219
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 220 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 272
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 273 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 323
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 324 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 382
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 383 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 417
Score = 61.2 bits (147), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 64 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 123
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 124 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 177
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 178 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 235
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 236 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 285
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 286 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 338
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 339 TVCNQLPNLQVLDLSYNLL-EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 395
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 396 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 443
>3w3j_A A Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4r09_D D Toll-like receptor 8
Length=811
Score = 74.7 bits (182), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4kng_B B Leucine-rich repeat-containing G-protein coupled receptor
5
Length=531
Score = 73.9 bits (180), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 25 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 72
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 73 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 124
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 125 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 184
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 185 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 218
Score = 69.7 bits (169), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 63 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 113
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 114 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 171
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 172 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 227
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 228 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 285
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 286 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 335
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 336 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 389
Score = 65.9 bits (159), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 167/395 (42%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 21 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 80
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 81 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 140
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 141 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 197
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 198 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 250
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 251 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 301
Query 330 KRSFTKQSISLASLPKI-------------------DDFSFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ D SF + L+ +++ N+I I
Sbjct 302 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 360
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 361 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 395
Score = 61.2 bits (147), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 42 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 101
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 102 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 155
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 156 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 213
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 214 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 263
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 264 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 316
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 317 TVCNQLPNLQVLDLSYNLL-EDLP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 373
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 374 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 421
>5uei_A A O13
Length=249
Score = 71.2 bits (173), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 55/181 (30%), Positives = 84/181 (46%), Gaps = 31/181 (17%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L+ L L +N L L P L+ L IL L
Sbjct 40 VLYLNDNQITKLEPGVFDRLVNLQTLWLNNNQLTSL--------PAGLFDSLTQLTILAL 91
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE--- 626
+SN +PV VF L +L+ + LG N L+ LP++VF+ V LK L + N +T +
Sbjct 92 DSNQLQALPVGVFGRLVDLQQLYLGSNQLSALPSAVFDRLVHLKELLMCCNKLTELPRGI 151
Query 627 ----------------KKVFGPAFRNLTELDMRF---NPFDCTCESIAWFVNWINETHTN 667
K + AF L+ L + NP+DC C I + NW+ + HT+
Sbjct 152 ERLTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD-HTS 210
Query 668 I 668
I
Sbjct 211 I 211
Score = 62.0 bits (149), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 60/207 (29%), Positives = 87/207 (42%), Gaps = 27/207 (13%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLD 81
+ ++C+ S +C L VP +PT VL L NQ
Sbjct 7 GACPSQCSCSGTTVNCKSKSLASVPAGIPTTTRVLYLNDNQ------------------- 47
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNN 141
I+KLEP + +L L+ L L +N+L+ L F T LT L L SN +Q +
Sbjct 48 -----ITKLEPGVFDRLVNLQTLWLNNNQLTSLPAGLFDSLTQLTILALDSNQLQALPVG 102
Query 142 PFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKK 201
F + +L L L N LS+ +L +L+ELL+ NK+ L I + L
Sbjct 103 VFGRLVDLQQLYLGSNQLSALPSAVFDRLVHLKELLMCCNKLTELPR---GIERLTHLTH 159
Query 202 LELSSNQIKEFSPGCFHAIGRLFGLFL 228
L L NQ+K G F + L +L
Sbjct 160 LALDQNQLKSIPHGAFDRLSSLTHAYL 186
Score = 36.6 bits (83), Expect = 0.97, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 56/115 (49%), Gaps = 5/115 (4%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I ++ +F L+NL+ L L+N+ L +L F SL L IL L N++
Sbjct 41 LYLNDNQITKLEPGVFDRLVNLQTLWLNNN--QLTSLPAGLFDSLTQ--LTILALDSNQL 96
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
+ F L L+ L LG N++ L + L ++ E+ + NK +L R
Sbjct 97 QALPVGVFGRLVDLQQLYLGSNQL-SALPSAVFDRLVHLKELLMCCNKLTELPRG 150
Score = 33.5 bits (75), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 43/155 (28%), Positives = 76/155 (49%), Gaps = 10/155 (6%)
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
L L+ N ++ + G +L NLQ L L+NN++ +L + D + L L L SNQ++
Sbjct 41 LYLNDNQITKLEPGVFDRLVNLQTLWLNNNQLTSLPAGLFDSL--TQLTILALDSNQLQA 98
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
G F + L L+L + QL +L + L + ++ L + ++L+ G+
Sbjct 99 LPVGVFGRLVDLQQLYLGSNQLS-ALPSAVFDRLVH--LKELLMCCNKLTELPR----GI 151
Query 272 -KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFL 305
+ T+LT L L N L + + +F L L + +L
Sbjct 152 ERLTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYL 186
>2id5_D D Leucine rich repeat neuronal 6A
Length=477
Score = 73.6 bits (179), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 83/364 (23%), Positives = 150/364 (41%), Gaps = 42/364 (12%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+ C + VP+ +P +L+L N+++ L F + L L++ N
Sbjct 8 ECSAQDRAVLCHRKRFVAVPEGIPXXXRLLDLGKNRIKTLNQDEFASFPHLEELELNENI 67
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+S +EP L L+ L L+ N L + F +NLT+L + N I + + F
Sbjct 68 VSAVEPGAFNNLFNLRTLGLRSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDL 127
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE-LS 205
NL +L++ N L L +L++L L + ++ +E L + +L L+
Sbjct 128 YNLKSLEVGDNDLVYISHRAFSGLNSLEQLTLEKCNLTSIPTEALSHLHGLIVLRLRHLN 187
Query 206 SNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSN 265
N I+++S RL+ L + + P L T +
Sbjct 188 INAIRDYS------FKRLYRLKVLEISHWP-----------------------YLDTMTP 218
Query 266 TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVR 325
GL NLT L +++ NL V + L L + L YN I + LH L ++
Sbjct 219 NCLYGL---NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQ 275
Query 326 YLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
+ L L ++ ++F+ L L LN+ N + ++ ++F + NL+ L
Sbjct 276 EIQLVG---------GQLAVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLI 326
Query 386 LSNS 389
L ++
Sbjct 327 LDSN 330
Score = 67.0 bits (162), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 89/340 (26%), Positives = 146/340 (43%), Gaps = 62/340 (18%)
Query 278 MLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK-- 335
+LDL N + + D FA P LE L N + + + + LFN+R L L+ + K
Sbjct 36 LLDLGKNRIKTLNQDEFASFPHLEELELNENIVSAVEPGAFNNLFNLRTLGLRSNRLKLI 95
Query 336 ---QSISLASLPKID----------DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
L++L K+D D+ FQ L L+ L + DND+ I F+GL +L+
Sbjct 96 PLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRAFSGLNSLE 155
Query 383 YLSLSNSFTSLRTLTNETFVSLAH-SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L+L LT+ +L+H L +L L I+ I +F L L+VL++
Sbjct 156 QLTLEKC-----NLTSIPTEALSHLHGLIVLRLRHLNINAIRDYSFKRLYRLKVLEI--- 207
Query 442 EIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP 501
W L+ +T N L L L +++ + + + P
Sbjct 208 --------SHWPYLDT-------------MTPN------CLYGLNLTSLSITHCNLTAVP 240
Query 502 FQPLRNLT---ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
+ +R+L L+LS N I+ I ML L +L+ + L LA + +A
Sbjct 241 YLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQLAVVEPYA--------F 292
Query 559 KGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+GL++L +LN+ N + VF + L+ + L N L
Sbjct 293 RGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPL 332
Score = 53.5 bits (127), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 57/208 (27%), Positives = 83/208 (40%), Gaps = 35/208 (17%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L+L KN+I + D F+ HLE L+L N + + E N+F + + L
Sbjct 35 RLLDLGKNRIKTLNQDEFASFPHLEELELNENIV----SAVEPGAFNNLFNL-----RTL 85
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L N L+P F L NLT LD+S N I + D M + L
Sbjct 86 GLRSNRLKLIPL------------------GVFTGLSNLTKLDISENKIVILLDYMFQDL 127
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
L+ L++ N+L + A GL+ L L LE IP E L L
Sbjct 128 YNLKSLEVGDNDLVYISHRA--------FSGLNSLEQLTLEKCNLTSIPTEALSHLHGLI 179
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNL 617
++ L N+N + F LK L +
Sbjct 180 VLRLRHLNINAIRDYSFKRLYRLKVLEI 207
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 36/121 (30%), Positives = 52/121 (43%), Gaps = 8/121 (7%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+LDL N I +N D LE L+L N + PG L +L L L
Sbjct 36 LLDLGKNRIKTLNQDEFASFPHLEELELNEN----IVSAVEPGA----FNNLFNLRTLGL 87
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN IP+ VF L L +D+ N + L +F + +LKSL + N + + +
Sbjct 88 RSNRLKLIPLGVFTGLSNLTKLDISENKIVILLDYMFQDLYNLKSLEVGDNDLVYISHRA 147
Query 630 F 630
F
Sbjct 148 F 148
Score = 36.2 bits (82), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 29/109 (27%), Positives = 51/109 (47%), Gaps = 0/109 (0%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+T L++TH L +P L L++ +N IS +E + +L L+ + L +L
Sbjct 225 NLTSLSITHCNLTAVPYLAVRHLVYLRFLNLSYNPISTIEGSMLHELLRLQEIQLVGGQL 284
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+ + F L L++ N + ++ + F NL TL L N L+
Sbjct 285 AVVEPYAFRGLNYLRVLNVSGNQLTTLEESVFHSVGNLETLILDSNPLA 333
>3w3n_B B Toll-like receptor 8
Length=811
Score = 74.3 bits (181), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4r07_A A Toll-like receptor 8
Length=811
Score = 74.3 bits (181), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4bsu_B B LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=539
Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 47 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 94
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 95 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 146
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 147 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 206
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 207 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 240
Score = 69.3 bits (168), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 85 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 135
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 136 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 193
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 194 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 249
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 250 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 307
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 308 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 357
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 358 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 411
Score = 65.9 bits (159), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 43 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 102
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 103 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 162
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 163 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 219
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 220 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 272
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 273 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 323
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 324 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 382
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 383 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 417
Score = 61.2 bits (147), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 64 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 123
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 124 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 177
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 178 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 235
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 236 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 285
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 286 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 338
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 339 TVCNQLPNLQVLDLSYNLL-EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 395
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 396 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 443
>4bsr_A A LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=539
Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 47 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 94
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 95 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 146
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 147 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 206
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 207 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 240
Score = 69.7 bits (169), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 93/356 (26%), Positives = 147/356 (41%), Gaps = 30/356 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 85 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 135
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 136 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 193
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 194 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 249
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 250 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 307
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 308 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 357
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 358 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAF 411
Score = 67.0 bits (162), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 101/417 (24%), Positives = 175/417 (42%), Gaps = 58/417 (14%)
Query 18 GMLCASSTTKCTVSHE-----VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFT 72
G+L T C + DCS L L+++P +L + L+L+ N + +L
Sbjct 21 GVLLRGCPTHCHCEPDGRMLLRVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLP 80
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMS 132
L L + N ++ + L LKVL LQ+N+L + + +L L L +
Sbjct 81 SLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDA 140
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N I + + F +L L L N L+ + L LQ + L+ NKI +
Sbjct 141 NHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA-- 198
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTS 249
F N SSL L L +N+I CF + L L L NN+ P+ L ++
Sbjct 199 -FGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SN 251
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEY 307
++ L ++ + + F+G N +++ + + N + VG +F LP+L L
Sbjct 252 LKELGFHSNNIRSIPEKAFVG----NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNG 307
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK------------------IDDF 349
+ F L G N+ S T ++SLP+ ++D
Sbjct 308 ASQITEFP-DLTGTANL------ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDL 360
Query 350 -SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS---------NSFTSLRTL 396
SF + L+ +++ N+I IK + F L++L+ L+L+ N+F++L +L
Sbjct 361 PSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 417
Score = 61.6 bits (148), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 64 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 123
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 124 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 177
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 178 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 235
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 236 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 285
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 286 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 338
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 339 TVCNQLPNLQVLDLSYNLL-EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 395
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 396 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 443
>5az5_A A Toll-like receptor 8
Length=811
Score = 74.3 bits (181), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>5az5_C C Toll-like receptor 8
Length=811
Score = 74.3 bits (181), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>5az5_B B Toll-like receptor 8
Length=811
Score = 74.3 bits (181), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4qc0_A A Toll-like receptor 8
Length=811
Score = 74.3 bits (181), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 190/807 (24%), Positives = 299/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXEFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>4bsr_B B LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR
5
Length=539
Score = 73.6 bits (179), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 69/215 (32%), Positives = 102/215 (47%), Gaps = 24/215 (11%)
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYL--SYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
DLGL+E+ L+ +F YL S N QL N +PSL+ L R+A
Sbjct 47 DLGLSELPSNLS---------VFTSYLDLSMNNISQLLPNP---LPSLRFLEELRLAGNA 94
Query 495 VDSSP-SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ P F L +L +L L NN + ++ + L+ L L+ L L N+++ +
Sbjct 95 LTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYV-------- 146
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P GL L L L+ N EIPV+ F+ L L+ + L LN ++ +P F N SL
Sbjct 147 PPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLV 206
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L+L N I S+ KK F +L LD+ +N D
Sbjct 207 VLHLHNNRIHSLGKKCFD-GLHSLETLDLNYNNLD 240
Score = 69.7 bits (169), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 93/357 (26%), Positives = 147/357 (41%), Gaps = 30/357 (8%)
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
L L L+ N L + +F L L+ L+ N ++H+ + +L L RS
Sbjct 85 LEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNL---------RSLQS 135
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+ + + F L L HL ++DN + I F L L+ ++L+ +
Sbjct 136 LRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLA--LNKIHH 193
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
+ + F +L S L +L+L N+I + F L LE LDL N + + T R L
Sbjct 194 IPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTA--IRTL 249
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
N+ E+ N + +F PSL + ++ V S FQ L L L L+
Sbjct 250 SNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSA--FQHLPELRTLTLNG 307
Query 516 -NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF 574
+ I D L G LE L L ++ L P L +L +L+L N
Sbjct 308 ASQITEFPD--LTGTANLESLTLTGAQISSL--------PQTVCNQLPNLQVLDLSYNLL 357
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
+++P F +L+ IDL N + + F +SL+SLNL N I + F
Sbjct 358 EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFS 412
Score = 66.6 bits (161), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 97/395 (25%), Positives = 169/395 (43%), Gaps = 53/395 (13%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPEL 94
DCS L L+++P +L + L+L+ N + +L L L + N ++ +
Sbjct 43 VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGA 102
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
L LKVL LQ+N+L + + +L L L +N I + + F +L L L
Sbjct 103 FTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWL 162
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFS 213
N L+ + L LQ + L+ NKI + F N SSL L L +N+I
Sbjct 163 DDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYA---FGNLSSLVVLHLHNNRIHSLG 219
Query 214 PGCFHAIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
CF + L L L NN+ P+ L ++++ L ++ + + F+G
Sbjct 220 KKCFDGLHSLETLDLNYNNLDEFPTAIRTL------SNLKELGFHSNNIRSIPEKAFVG- 272
Query 272 KWTNLTMLDLSY--NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N +++ + + N + VG +F LP+L L + F L G N+
Sbjct 273 ---NPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP-DLTGTANL----- 323
Query 330 KRSFTKQSISLASLPK------------------IDDF-SFQWLKCLEHLNMEDNDIPGI 370
S T ++SLP+ ++D SF + L+ +++ N+I I
Sbjct 324 -ESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEI 382
Query 371 KSNMFTGLINLKYLSLS---------NSFTSLRTL 396
K + F L++L+ L+L+ N+F++L +L
Sbjct 383 KVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSL 417
Score = 61.6 bits (148), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 107/412 (26%), Positives = 197/412 (48%), Gaps = 37/412 (9%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L N+I ++ NP + L L L+ N L+ G L +L+ L+L NN+++ +
Sbjct 64 LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVP 123
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN 247
+E L SL+ L L +N I P CF + L L+L++ +LTE +
Sbjct 124 TEALQNL--RSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDN----ALTEIPVQAFRS 177
Query 248 -TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
++++ ++L+ +++ + F L ++L +L L N ++ +G F L LE L
Sbjct 178 LSALQAMTLALNKIHHIPDYAFGNL--SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLN 235
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
YNN+ F ++ L N++ L S ++ S+P + +F L ++ DN
Sbjct 236 YNNLDE-FPTAIRTLSNLKELGF------HSNNIRSIP---EKAFVGNPSLITIHFYDNP 285
Query 367 IPGIKSNMFTGLINLKYLSLSNS--FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
I + + F L L+ L+L+ + T LT + L L LT +IS +
Sbjct 286 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-------ANLESLTLTGAQISSLPQ 338
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
+ L +L+VLDL N + ++L + + + +I L +N+ ++ ++F + SL+
Sbjct 339 TVCNQLPNLQVLDLSYNLL-EDLPS--FSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRS 395
Query 485 LML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
L L ++A+ + P+ F L +L LDLS+N +++ L GL L++
Sbjct 396 LNLAWNKIAIIH----PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKL 443
>4r08_B B Toll-like receptor 8
Length=811
Score = 73.9 bits (180), Expect = 4e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKV-FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSAXXXXXXXKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>5uf1_B A O13
Length=247
Score = 70.9 bits (172), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 55/181 (30%), Positives = 84/181 (46%), Gaps = 31/181 (17%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L+ L L +N L L P L+ L IL L
Sbjct 38 VLYLNDNQITKLEPGVFDRLVNLQTLWLNNNQLTSL--------PAGLFDSLTQLTILAL 89
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE--- 626
+SN +PV VF L +L+ + LG N L+ LP++VF+ V LK L + N +T +
Sbjct 90 DSNQLQALPVGVFGRLVDLQQLYLGSNQLSALPSAVFDRLVHLKELLMCCNKLTELPRGI 149
Query 627 ----------------KKVFGPAFRNLTELDMRF---NPFDCTCESIAWFVNWINETHTN 667
K + AF L+ L + NP+DC C I + NW+ + HT+
Sbjct 150 ERLTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD-HTS 208
Query 668 I 668
I
Sbjct 209 I 209
Score = 61.6 bits (148), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 60/203 (30%), Positives = 86/203 (42%), Gaps = 27/203 (13%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S +C L VP +PT VL L NQ
Sbjct 9 SQCSCSGTTVNCKSKSLASVPAGIPTTTRVLYLNDNQ----------------------- 45
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
I+KLEP + +L L+ L L +N+L+ L F T LT L L SN +Q + F +
Sbjct 46 -ITKLEPGVFDRLVNLQTLWLNNNQLTSLPAGLFDSLTQLTILALDSNQLQALPVGVFGR 104
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
+L L L N LS+ +L +L+ELL+ NK+ L I + L L L
Sbjct 105 LVDLQQLYLGSNQLSALPSAVFDRLVHLKELLMCCNKLTELPR---GIERLTHLTHLALD 161
Query 206 SNQIKEFSPGCFHAIGRLFGLFL 228
NQ+K G F + L +L
Sbjct 162 QNQLKSIPHGAFDRLSSLTHAYL 184
Score = 36.6 bits (83), Expect = 0.99, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 56/115 (49%), Gaps = 5/115 (4%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I ++ +F L+NL+ L L+N+ L +L F SL L IL L N++
Sbjct 39 LYLNDNQITKLEPGVFDRLVNLQTLWLNNN--QLTSLPAGLFDSLTQ--LTILALDSNQL 94
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
+ F L L+ L LG N++ L + L ++ E+ + NK +L R
Sbjct 95 QALPVGVFGRLVDLQQLYLGSNQL-SALPSAVFDRLVHLKELLMCCNKLTELPRG 148
>5uf1_A B O13
Length=247
Score = 70.9 bits (172), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 55/181 (30%), Positives = 84/181 (46%), Gaps = 31/181 (17%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L+ L L +N L L P L+ L IL L
Sbjct 38 VLYLNDNQITKLEPGVFDRLVNLQTLWLNNNQLTSL--------PAGLFDSLTQLTILAL 89
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE--- 626
+SN +PV VF L +L+ + LG N L+ LP++VF+ V LK L + N +T +
Sbjct 90 DSNQLQALPVGVFGRLVDLQQLYLGSNQLSALPSAVFDRLVHLKELLMCCNKLTELPRGI 149
Query 627 ----------------KKVFGPAFRNLTELDMRF---NPFDCTCESIAWFVNWINETHTN 667
K + AF L+ L + NP+DC C I + NW+ + HT+
Sbjct 150 ERLTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD-HTS 208
Query 668 I 668
I
Sbjct 209 I 209
Score = 61.6 bits (148), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 60/203 (30%), Positives = 86/203 (42%), Gaps = 27/203 (13%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S +C L VP +PT VL L NQ
Sbjct 9 SQCSCSGTTVNCKSKSLASVPAGIPTTTRVLYLNDNQ----------------------- 45
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
I+KLEP + +L L+ L L +N+L+ L F T LT L L SN +Q + F +
Sbjct 46 -ITKLEPGVFDRLVNLQTLWLNNNQLTSLPAGLFDSLTQLTILALDSNQLQALPVGVFGR 104
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
+L L L N LS+ +L +L+ELL+ NK+ L I + L L L
Sbjct 105 LVDLQQLYLGSNQLSALPSAVFDRLVHLKELLMCCNKLTELPR---GIERLTHLTHLALD 161
Query 206 SNQIKEFSPGCFHAIGRLFGLFL 228
NQ+K G F + L +L
Sbjct 162 QNQLKSIPHGAFDRLSSLTHAYL 184
Score = 36.6 bits (83), Expect = 0.99, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 56/115 (49%), Gaps = 5/115 (4%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I ++ +F L+NL+ L L+N+ L +L F SL L IL L N++
Sbjct 39 LYLNDNQITKLEPGVFDRLVNLQTLWLNNN--QLTSLPAGLFDSLTQ--LTILALDSNQL 94
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
+ F L L+ L LG N++ L + L ++ E+ + NK +L R
Sbjct 95 QALPVGVFGRLVDLQQLYLGSNQL-SALPSAVFDRLVHLKELLMCCNKLTELPRG 148
>5uf4_A A O13
Length=249
Score = 70.9 bits (172), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 55/181 (30%), Positives = 84/181 (46%), Gaps = 31/181 (17%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L+ L L +N L L P L+ L IL L
Sbjct 40 VLYLNDNQITKLEPGVFDRLVNLQTLWLNNNQLTSL--------PAGLFDSLTQLTILAL 91
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE--- 626
+SN +PV VF L +L+ + LG N L+ LP++VF+ V LK L + N +T +
Sbjct 92 DSNQLQALPVGVFGRLVDLQQLYLGSNQLSALPSAVFDRLVHLKELLMCCNKLTELPRGI 151
Query 627 ----------------KKVFGPAFRNLTELDMRF---NPFDCTCESIAWFVNWINETHTN 667
K + AF L+ L + NP+DC C I + NW+ + HT+
Sbjct 152 ERLTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD-HTS 210
Query 668 I 668
I
Sbjct 211 I 211
Score = 61.6 bits (148), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 60/203 (30%), Positives = 86/203 (42%), Gaps = 27/203 (13%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S +C L VP +PT VL L NQ
Sbjct 11 SQCSCSGTTVNCKSKSLASVPAGIPTTTRVLYLNDNQ----------------------- 47
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
I+KLEP + +L L+ L L +N+L+ L F T LT L L SN +Q + F +
Sbjct 48 -ITKLEPGVFDRLVNLQTLWLNNNQLTSLPAGLFDSLTQLTILALDSNQLQALPVGVFGR 106
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
+L L L N LS+ +L +L+ELL+ NK+ L I + L L L
Sbjct 107 LVDLQQLYLGSNQLSALPSAVFDRLVHLKELLMCCNKLTELPR---GIERLTHLTHLALD 163
Query 206 SNQIKEFSPGCFHAIGRLFGLFL 228
NQ+K G F + L +L
Sbjct 164 QNQLKSIPHGAFDRLSSLTHAYL 186
Score = 36.6 bits (83), Expect = 1.00, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 56/115 (49%), Gaps = 5/115 (4%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I ++ +F L+NL+ L L+N+ L +L F SL L IL L N++
Sbjct 41 LYLNDNQITKLEPGVFDRLVNLQTLWLNNN--QLTSLPAGLFDSLTQ--LTILALDSNQL 96
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
+ F L L+ L LG N++ L + L ++ E+ + NK +L R
Sbjct 97 QALPVGVFGRLVDLQQLYLGSNQL-SALPSAVFDRLVHLKELLMCCNKLTELPRG 150
>5uf4_B B O13
Length=249
Score = 70.9 bits (172), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 55/181 (30%), Positives = 84/181 (46%), Gaps = 31/181 (17%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L+ L L +N L L P L+ L IL L
Sbjct 40 VLYLNDNQITKLEPGVFDRLVNLQTLWLNNNQLTSL--------PAGLFDSLTQLTILAL 91
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE--- 626
+SN +PV VF L +L+ + LG N L+ LP++VF+ V LK L + N +T +
Sbjct 92 DSNQLQALPVGVFGRLVDLQQLYLGSNQLSALPSAVFDRLVHLKELLMCCNKLTELPRGI 151
Query 627 ----------------KKVFGPAFRNLTELDMRF---NPFDCTCESIAWFVNWINETHTN 667
K + AF L+ L + NP+DC C I + NW+ + HT+
Sbjct 152 ERLTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD-HTS 210
Query 668 I 668
I
Sbjct 211 I 211
Score = 61.6 bits (148), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 60/203 (30%), Positives = 86/203 (42%), Gaps = 27/203 (13%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S +C L VP +PT VL L NQ
Sbjct 11 SQCSCSGTTVNCKSKSLASVPAGIPTTTRVLYLNDNQ----------------------- 47
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
I+KLEP + +L L+ L L +N+L+ L F T LT L L SN +Q + F +
Sbjct 48 -ITKLEPGVFDRLVNLQTLWLNNNQLTSLPAGLFDSLTQLTILALDSNQLQALPVGVFGR 106
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
+L L L N LS+ +L +L+ELL+ NK+ L I + L L L
Sbjct 107 LVDLQQLYLGSNQLSALPSAVFDRLVHLKELLMCCNKLTELPR---GIERLTHLTHLALD 163
Query 206 SNQIKEFSPGCFHAIGRLFGLFL 228
NQ+K G F + L +L
Sbjct 164 QNQLKSIPHGAFDRLSSLTHAYL 186
Score = 36.6 bits (83), Expect = 1.00, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 56/115 (49%), Gaps = 5/115 (4%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I ++ +F L+NL+ L L+N+ L +L F SL L IL L N++
Sbjct 41 LYLNDNQITKLEPGVFDRLVNLQTLWLNNN--QLTSLPAGLFDSLTQ--LTILALDSNQL 96
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
+ F L L+ L LG N++ L + L ++ E+ + NK +L R
Sbjct 97 QALPVGVFGRLVDLQQLYLGSNQL-SALPSAVFDRLVHLKELLMCCNKLTELPRG 150
>5uf4_C C O13
Length=249
Score = 70.9 bits (172), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 55/181 (30%), Positives = 84/181 (46%), Gaps = 31/181 (17%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L+ L L +N L L P L+ L IL L
Sbjct 40 VLYLNDNQITKLEPGVFDRLVNLQTLWLNNNQLTSL--------PAGLFDSLTQLTILAL 91
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE--- 626
+SN +PV VF L +L+ + LG N L+ LP++VF+ V LK L + N +T +
Sbjct 92 DSNQLQALPVGVFGRLVDLQQLYLGSNQLSALPSAVFDRLVHLKELLMCCNKLTELPRGI 151
Query 627 ----------------KKVFGPAFRNLTELDMRF---NPFDCTCESIAWFVNWINETHTN 667
K + AF L+ L + NP+DC C I + NW+ + HT+
Sbjct 152 ERLTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD-HTS 210
Query 668 I 668
I
Sbjct 211 I 211
Score = 61.6 bits (148), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 60/203 (30%), Positives = 86/203 (42%), Gaps = 27/203 (13%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S +C L VP +PT VL L NQ
Sbjct 11 SQCSCSGTTVNCKSKSLASVPAGIPTTTRVLYLNDNQ----------------------- 47
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
I+KLEP + +L L+ L L +N+L+ L F T LT L L SN +Q + F +
Sbjct 48 -ITKLEPGVFDRLVNLQTLWLNNNQLTSLPAGLFDSLTQLTILALDSNQLQALPVGVFGR 106
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
+L L L N LS+ +L +L+ELL+ NK+ L I + L L L
Sbjct 107 LVDLQQLYLGSNQLSALPSAVFDRLVHLKELLMCCNKLTELPR---GIERLTHLTHLALD 163
Query 206 SNQIKEFSPGCFHAIGRLFGLFL 228
NQ+K G F + L +L
Sbjct 164 QNQLKSIPHGAFDRLSSLTHAYL 186
Score = 36.6 bits (83), Expect = 1.00, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 56/115 (49%), Gaps = 5/115 (4%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I ++ +F L+NL+ L L+N+ L +L F SL L IL L N++
Sbjct 41 LYLNDNQITKLEPGVFDRLVNLQTLWLNNN--QLTSLPAGLFDSLTQ--LTILALDSNQL 96
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
+ F L L+ L LG N++ L + L ++ E+ + NK +L R
Sbjct 97 QALPVGVFGRLVDLQQLYLGSNQL-SALPSAVFDRLVHLKELLMCCNKLTELPRG 150
>5b4p_A A repebody
Length=261
Score = 70.9 bits (172), Expect = 5e-12, Method: Compositional matrix adjust.
Identities = 65/211 (31%), Positives = 96/211 (45%), Gaps = 19/211 (9%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L L L ++ S + L NLT L L N + + + + + L L+ L L
Sbjct 64 LPNVRYLALGGNKLHDI----SALKELTNLTYLFLDFNQL-QLPNGVFDKLTNLKELYLS 118
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P L++L IL L+ N +P VF L L +DL N L
Sbjct 119 PNQLQSL--------PDGVFDKLTNLTILGLDMNQLQSLPKGVFDKLTNLTELDLSYNQL 170
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L+L N + SV VF +L + + NP+DCTC I +
Sbjct 171 QSLPKGVFDKLTQLKDLSLSYNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRYLS 229
Query 659 NWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
WIN+ H+ + C+ G PVR
Sbjct 230 EWINK-HSGVVGGPDSAKCSG----SGKPVR 255
Score = 58.9 bits (141), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 62/187 (33%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L + FN +
Sbjct 44 SIDQIIANNSDIKSVQGIQYLP-NVRYLALGGNKLHDISA--LKELTNLTYLFLDFNQL- 99
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
+L + KL LK L L N+L L D F TNLT L L N +Q + F K N
Sbjct 100 QLPNGVFDKLTNLKELYLSPNQLQSLPDGVFDKLTNLTILGLDMNQLQSLPKGVFDKLTN 159
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
L LDLS+N L S G +L L++L LS N+++++ D +SL+ + L N
Sbjct 160 LTELDLSYNQLQSLPKGVFDKLTQLKDLSLSYNQLKSVPDGVFDRL--TSLQYIWLHDNP 217
Query 209 IKEFSPG 215
PG
Sbjct 218 WDCTCPG 224
Score = 44.7 bits (104), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 50/142 (35%), Positives = 69/142 (49%), Gaps = 12/142 (8%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL--FGL 226
+L NL L L N++Q L + D N LK+L LS NQ++ G F + L GL
Sbjct 85 ELTNLTYLFLDFNQLQ-LPNGVFDKLTN--LKELYLSPNQLQSLPDGVFDKLTNLTILGL 141
Query 227 FLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL 286
+N +Q SL + + +L N + L LS +QL + F K T L L LSYN L
Sbjct 142 DMNQLQ---SLPKGVFDKLTN--LTELDLSYNQLQSLPKGVFD--KLTQLKDLSLSYNQL 194
Query 287 NVVGNDSFAWLPQLEYFFLEYN 308
V + F L L+Y +L N
Sbjct 195 KSVPDGVFDRLTSLQYIWLHDN 216
Score = 43.5 bits (101), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 51/159 (32%), Positives = 79/159 (50%), Gaps = 12/159 (8%)
Query 170 LENLQELLLSNNKIQALKS-EELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
L N++ L L NK+ + + +EL ++L L L NQ+ + G F + L L+L
Sbjct 64 LPNVRYLALGGNKLHDISALKEL-----TNLTYLFLDFNQL-QLPNGVFDKLTNLKELYL 117
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
+ QL SL + + +L N +I L L +QL + F K TNLT LDLSYN L
Sbjct 118 SPNQLQ-SLPDGVFDKLTNLTI--LGLDMNQLQSLPKGVFD--KLTNLTELDLSYNQLQS 172
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
+ F L QL+ L YN ++ + L +++Y+
Sbjct 173 LPKGVFDKLTQLKDLSLSYNQLKSVPDGVFDRLTSLQYI 211
>4r6a_A A Toll-like receptor 8
Length=811
Score = 73.6 bits (179), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSAXXXXXXTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4r07_B B Toll-like receptor 8
Length=811
Score = 73.6 bits (179), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKXXXXXXXXTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>5z14_B B Toll-like receptor 8
Length=811
Score = 73.6 bits (179), Expect = 6e-12, Method: Compositional matrix adjust.
Identities = 187/807 (23%), Positives = 300/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPXXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSL 482
+ F L + L+L N Q L+G E+ + ++ KYL LT N +
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 483 QRLMLRRVALKNVDSSPSPF------------QPLRNLTILDLSNNNIANINDDM-LEGL 529
L + + ++ + F Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFXXXGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEK-KVFGPAFRNLTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINKXXXXXXXXXKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>5z15_A A Toll-like receptor 8
Length=811
Score = 73.6 bits (179), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 190/807 (24%), Positives = 299/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINKSALXXXXXTKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>7ytx_B B Toll-like receptor 8
Length=811
Score = 73.6 bits (179), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 194/805 (24%), Positives = 302/805 (38%), Gaps = 192/805 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
+ DDF L L +N+ N I I +F NL+ + LS + S L +T
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRIS--PLVKDTX 416
Query 402 VSL---------------------AHS-------PL---------HILNLTKNKISKIES 424
HS PL L+L+ N I I
Sbjct 417 XXXXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGP 476
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSL 482
+ F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 477 NQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASAL 528
Query 483 QRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEK 531
L V + V Q NL +L+LS+NNI + D LE
Sbjct 529 TELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSL 588
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFE 587
+E++ N L LW + + I KGL +L L+L N IP E F L E
Sbjct 589 VELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTE 646
Query 588 LKIID---------------------------------------------LGLNNLNTLP 602
L I D L N ++ LP
Sbjct 647 LHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLP 706
Query 603 ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNWI 661
+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W+
Sbjct 707 SGFLSEVSSLKHLDLSSNLLKTINKSAXXXXXXTKLSMLELHGNPFECTCD-IGDFRRWM 765
Query 662 NE-THTNIPELSSHYLCNTPPHYHG 685
+E + IP L +C +P G
Sbjct 766 DEHLNVKIPRLVD-VICASPGDQRG 789
>3w3g_A A Toll-like receptor 8
Length=811
Score = 73.6 bits (179), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 190/807 (24%), Positives = 299/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>4r6a_B B Toll-like receptor 8
Length=811
Score = 73.2 bits (178), Expect = 7e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSXXXXXXTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4r0a_A A Toll-like receptor 8
Length=811
Score = 73.2 bits (178), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNET 400
+ DDF L L +N+ N I I +F NL+ + LS N + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 401 FVSL------------------AHS-------PL---------HILNLTKNKISKIESDA 426
HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXXEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4qc0_B B Toll-like receptor 8
Length=811
Score = 73.2 bits (178), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 190/807 (24%), Positives = 299/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXEFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>7ytx_A A Toll-like receptor 8
Length=811
Score = 73.2 bits (178), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 190/807 (24%), Positives = 299/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>5b4p_C C repebody
Length=261
Score = 70.5 bits (171), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 65/211 (31%), Positives = 96/211 (45%), Gaps = 19/211 (9%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L L L ++ S + L NLT L L N + + + + + L L+ L L
Sbjct 64 LPNVRYLALGGNKLHDI----SALKELTNLTYLFLDFNQL-QLPNGVFDKLTNLKELYLS 118
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P L++L IL L+ N +P VF L L +DL N L
Sbjct 119 PNQLQSL--------PDGVFDKLTNLTILGLDMNQLQSLPKGVFDKLTNLTELDLSYNQL 170
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L+L N + SV VF +L + + NP+DCTC I +
Sbjct 171 QSLPKGVFDKLTQLKDLSLSYNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPXIRYLS 229
Query 659 NWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
WIN+ H+ + C+ G PVR
Sbjct 230 EWINK-HSGVVGGPDSAKCSG----SGKPVR 255
Score = 58.2 bits (139), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 56/164 (34%), Positives = 81/164 (49%), Gaps = 4/164 (2%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L + FN +
Sbjct 44 SIDQIIANNSDIKSVQGIQYLP-NVRYLALGGNKLHDISA--LKELTNLTYLFLDFNQL- 99
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
+L + KL LK L L N+L L D F TNLT L L N +Q + F K N
Sbjct 100 QLPNGVFDKLTNLKELYLSPNQLQSLPDGVFDKLTNLTILGLDMNQLQSLPKGVFDKLTN 159
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
L LDLS+N L S G +L L++L LS N+++++ D
Sbjct 160 LTELDLSYNQLQSLPKGVFDKLTQLKDLSLSYNQLKSVPDGVFD 203
Score = 57.8 bits (138), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 48/131 (37%), Positives = 64/131 (49%), Gaps = 1/131 (1%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T L L NQL+ LP F + + L L + N + L + KL L +L L N+
Sbjct 87 TNLTYLFLDFNQLQ-LPNGVFDKLTNLKELYLSPNQLQSLPDGVFDKLTNLTILGLDMNQ 145
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L F TNLTEL L N +Q + F K L L LS+N L S G +L
Sbjct 146 LQSLPKGVFDKLTNLTELDLSYNQLQSLPKGVFDKLTQLKDLSLSYNQLKSVPDGVFDRL 205
Query 171 ENLQELLLSNN 181
+LQ + L +N
Sbjct 206 TSLQYIWLHDN 216
Score = 55.1 bits (131), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 35/96 (36%), Positives = 52/96 (54%), Gaps = 3/96 (3%)
Query 41 KLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
+L +PD D TN+T+L L NQL+ LP F + + LT LD+ +N + L + K
Sbjct 121 QLQSLPDGVFDKLTNLTILGLDMNQLQSLPKGVFDKLTNLTELDLSYNQLQSLPKGVFDK 180
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
L LK L+L +N+L + D F T+L + L N
Sbjct 181 LTQLKDLSLSYNQLKSVPDGVFDRLTSLQYIWLHDN 216
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 50/143 (35%), Positives = 69/143 (48%), Gaps = 14/143 (10%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL--FGL 226
+L NL L L N++Q L + D N LK+L LS NQ++ G F + L GL
Sbjct 85 ELTNLTYLFLDFNQLQ-LPNGVFDKLTN--LKELYLSPNQLQSLPDGVFDKLTNLTILGL 141
Query 227 FLNNVQLGP-SLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNN 285
+N +Q P + +KL T++ L LS +QL + F K T L L LSYN
Sbjct 142 DMNQLQSLPKGVFDKL------TNLTELDLSYNQLQSLPKGVFD--KLTQLKDLSLSYNQ 193
Query 286 LNVVGNDSFAWLPQLEYFFLEYN 308
L V + F L L+Y +L N
Sbjct 194 LKSVPDGVFDRLTSLQYIWLHDN 216
Score = 43.9 bits (102), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 51/159 (32%), Positives = 79/159 (50%), Gaps = 12/159 (8%)
Query 170 LENLQELLLSNNKIQALKS-EELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
L N++ L L NK+ + + +EL ++L L L NQ+ + G F + L L+L
Sbjct 64 LPNVRYLALGGNKLHDISALKEL-----TNLTYLFLDFNQL-QLPNGVFDKLTNLKELYL 117
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
+ QL SL + + +L N +I L L +QL + F K TNLT LDLSYN L
Sbjct 118 SPNQLQ-SLPDGVFDKLTNLTI--LGLDMNQLQSLPKGVFD--KLTNLTELDLSYNQLQS 172
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
+ F L QL+ L YN ++ + L +++Y+
Sbjct 173 LPKGVFDKLTQLKDLSLSYNQLKSVPDGVFDRLTSLQYI 211
>5wyx_A A Toll-like receptor 8
Length=811
Score = 73.2 bits (178), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 190/807 (24%), Positives = 299/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>5wyz_A A Toll-like receptor 8
Length=811
Score = 73.2 bits (178), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 190/807 (24%), Positives = 299/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>4r07_D D Toll-like receptor 8
Length=811
Score = 73.2 bits (178), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 193/803 (24%), Positives = 300/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEK-KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKXXXXXXXXXXLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>3w3g_B B Toll-like receptor 8
Length=811
Score = 73.2 bits (178), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 190/807 (24%), Positives = 298/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVN 659
LP+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFXXXXSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>5ufb_A A Tn4-22
Length=248
Score = 69.7 bits (169), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 57/184 (31%), Positives = 81/184 (44%), Gaps = 31/184 (17%)
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
N+ IL+L NN I N+ + + L L+ L L N L L P+ LS L
Sbjct 37 NVQILNLYNNQITNLEPGVFDRLVNLQKLYLSGNQLQAL--------PVGVFDKLSQLTF 88
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
L+L+ N +P VF L EL ++L N L LP VF+ V LK L + N +T +
Sbjct 89 LSLDENKLTALPNGVFDKLTELTYLNLNTNQLTALPEGVFDRLVHLKELLMCCNKLTELP 148
Query 627 -------------------KKVFGPAFRNLTELDMRF---NPFDCTCESIAWFVNWINET 664
K + AF L+ L + NP+DC C I + NW+ +
Sbjct 149 RGIERLTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD- 207
Query 665 HTNI 668
HT+I
Sbjct 208 HTSI 211
Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 27/203 (13%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ DC +L VP +PTN+ +LNL +NQ
Sbjct 11 SQCSCRGTYVDCDSRRLASVPAGIPTNVQILNLYNNQ----------------------- 47
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
I+ LEP + +L L+ L L N+L L F + LT L L N + + N F K
Sbjct 48 -ITNLEPGVFDRLVNLQKLYLSGNQLQALPVGVFDKLSQLTFLSLDENKLTALPNGVFDK 106
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
L L+L+ N L++ G +L +L+ELL+ NK+ L I + L L L
Sbjct 107 LTELTYLNLNTNQLTALPEGVFDRLVHLKELLMCCNKLTELPR---GIERLTHLTHLALD 163
Query 206 SNQIKEFSPGCFHAIGRLFGLFL 228
NQ+K G F + L +L
Sbjct 164 QNQLKSIPHGAFDRLSSLTHAYL 186
Score = 36.6 bits (83), Expect = 0.83, Method: Compositional matrix adjust.
Identities = 27/79 (34%), Positives = 40/79 (51%), Gaps = 4/79 (5%)
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
+++ ILNL +N + VF L L+ + L N L LP VF+ L L+L +N
Sbjct 36 TNVQILNLYNNQITNLEPGVFDRLVNLQKLYLSGNQLQALPVGVFDKLSQLTFLSLDENK 95
Query 622 ITSVEKKVFGPAFRNLTEL 640
+T++ VF LTEL
Sbjct 96 LTALPNGVFD----KLTEL 110
Score = 35.8 bits (81), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 5/115 (4%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
LN+ +N I ++ +F L+NL+ L LS + L+ L F L S L L+L +NK+
Sbjct 41 LNLYNNQITNLEPGVFDRLVNLQKLYLSGN--QLQALPVGVFDKL--SQLTFLSLDENKL 96
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
+ + + F L L L+L N++ G R L ++ E+ + NK +L R
Sbjct 97 TALPNGVFDKLTELTYLNLNTNQLTALPEGVFDR-LVHLKELLMCCNKLTELPRG 150
>5ufc_A A Tn4-22
Length=248
Score = 69.7 bits (169), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 57/184 (31%), Positives = 81/184 (44%), Gaps = 31/184 (17%)
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
N+ IL+L NN I N+ + + L L+ L L N L L P+ LS L
Sbjct 37 NVQILNLYNNQITNLEPGVFDRLVNLQKLYLSGNQLQAL--------PVGVFDKLSQLTF 88
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
L+L+ N +P VF L EL ++L N L LP VF+ V LK L + N +T +
Sbjct 89 LSLDENKLTALPNGVFDKLTELTYLNLNTNQLTALPEGVFDRLVHLKELLMCCNKLTELP 148
Query 627 -------------------KKVFGPAFRNLTELDMRF---NPFDCTCESIAWFVNWINET 664
K + AF L+ L + NP+DC C I + NW+ +
Sbjct 149 RGIERLTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD- 207
Query 665 HTNI 668
HT+I
Sbjct 208 HTSI 211
Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 27/203 (13%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ DC +L VP +PTN+ +LNL +NQ
Sbjct 11 SQCSCRGTYVDCDSRRLASVPAGIPTNVQILNLYNNQ----------------------- 47
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
I+ LEP + +L L+ L L N+L L F + LT L L N + + N F K
Sbjct 48 -ITNLEPGVFDRLVNLQKLYLSGNQLQALPVGVFDKLSQLTFLSLDENKLTALPNGVFDK 106
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
L L+L+ N L++ G +L +L+ELL+ NK+ L I + L L L
Sbjct 107 LTELTYLNLNTNQLTALPEGVFDRLVHLKELLMCCNKLTELPR---GIERLTHLTHLALD 163
Query 206 SNQIKEFSPGCFHAIGRLFGLFL 228
NQ+K G F + L +L
Sbjct 164 QNQLKSIPHGAFDRLSSLTHAYL 186
Score = 36.6 bits (83), Expect = 0.80, Method: Compositional matrix adjust.
Identities = 27/79 (34%), Positives = 40/79 (51%), Gaps = 4/79 (5%)
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
+++ ILNL +N + VF L L+ + L N L LP VF+ L L+L +N
Sbjct 36 TNVQILNLYNNQITNLEPGVFDRLVNLQKLYLSGNQLQALPVGVFDKLSQLTFLSLDENK 95
Query 622 ITSVEKKVFGPAFRNLTEL 640
+T++ VF LTEL
Sbjct 96 LTALPNGVFD----KLTEL 110
Score = 35.8 bits (81), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 5/115 (4%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
LN+ +N I ++ +F L+NL+ L LS + L+ L F L S L L+L +NK+
Sbjct 41 LNLYNNQITNLEPGVFDRLVNLQKLYLSGN--QLQALPVGVFDKL--SQLTFLSLDENKL 96
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
+ + + F L L L+L N++ G R L ++ E+ + NK +L R
Sbjct 97 TALPNGVFDKLTELTYLNLNTNQLTALPEGVFDR-LVHLKELLMCCNKLTELPRG 150
>5ufc_C C Tn4-22
Length=248
Score = 69.7 bits (169), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 57/184 (31%), Positives = 81/184 (44%), Gaps = 31/184 (17%)
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
N+ IL+L NN I N+ + + L L+ L L N L L P+ LS L
Sbjct 37 NVQILNLYNNQITNLEPGVFDRLVNLQKLYLSGNQLQAL--------PVGVFDKLSQLTF 88
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
L+L+ N +P VF L EL ++L N L LP VF+ V LK L + N +T +
Sbjct 89 LSLDENKLTALPNGVFDKLTELTYLNLNTNQLTALPEGVFDRLVHLKELLMCCNKLTELP 148
Query 627 -------------------KKVFGPAFRNLTELDMRF---NPFDCTCESIAWFVNWINET 664
K + AF L+ L + NP+DC C I + NW+ +
Sbjct 149 RGIERLTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD- 207
Query 665 HTNI 668
HT+I
Sbjct 208 HTSI 211
Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 27/203 (13%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ DC +L VP +PTN+ +LNL +NQ
Sbjct 11 SQCSCRGTYVDCDSRRLASVPAGIPTNVQILNLYNNQ----------------------- 47
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
I+ LEP + +L L+ L L N+L L F + LT L L N + + N F K
Sbjct 48 -ITNLEPGVFDRLVNLQKLYLSGNQLQALPVGVFDKLSQLTFLSLDENKLTALPNGVFDK 106
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
L L+L+ N L++ G +L +L+ELL+ NK+ L I + L L L
Sbjct 107 LTELTYLNLNTNQLTALPEGVFDRLVHLKELLMCCNKLTELPR---GIERLTHLTHLALD 163
Query 206 SNQIKEFSPGCFHAIGRLFGLFL 228
NQ+K G F + L +L
Sbjct 164 QNQLKSIPHGAFDRLSSLTHAYL 186
Score = 36.6 bits (83), Expect = 0.80, Method: Compositional matrix adjust.
Identities = 27/79 (34%), Positives = 40/79 (51%), Gaps = 4/79 (5%)
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
+++ ILNL +N + VF L L+ + L N L LP VF+ L L+L +N
Sbjct 36 TNVQILNLYNNQITNLEPGVFDRLVNLQKLYLSGNQLQALPVGVFDKLSQLTFLSLDENK 95
Query 622 ITSVEKKVFGPAFRNLTEL 640
+T++ VF LTEL
Sbjct 96 LTALPNGVFD----KLTEL 110
Score = 35.8 bits (81), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 5/115 (4%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
LN+ +N I ++ +F L+NL+ L LS + L+ L F L S L L+L +NK+
Sbjct 41 LNLYNNQITNLEPGVFDRLVNLQKLYLSGN--QLQALPVGVFDKL--SQLTFLSLDENKL 96
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
+ + + F L L L+L N++ G R L ++ E+ + NK +L R
Sbjct 97 TALPNGVFDKLTELTYLNLNTNQLTALPEGVFDR-LVHLKELLMCCNKLTELPRG 150
>5ufc_B B Tn4-22
Length=248
Score = 69.7 bits (169), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 57/184 (31%), Positives = 81/184 (44%), Gaps = 31/184 (17%)
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
N+ IL+L NN I N+ + + L L+ L L N L L P+ LS L
Sbjct 37 NVQILNLYNNQITNLEPGVFDRLVNLQKLYLSGNQLQAL--------PVGVFDKLSQLTF 88
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
L+L+ N +P VF L EL ++L N L LP VF+ V LK L + N +T +
Sbjct 89 LSLDENKLTALPNGVFDKLTELTYLNLNTNQLTALPEGVFDRLVHLKELLMCCNKLTELP 148
Query 627 -------------------KKVFGPAFRNLTELDMRF---NPFDCTCESIAWFVNWINET 664
K + AF L+ L + NP+DC C I + NW+ +
Sbjct 149 RGIERLTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD- 207
Query 665 HTNI 668
HT+I
Sbjct 208 HTSI 211
Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 27/203 (13%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ DC +L VP +PTN+ +LNL +NQ
Sbjct 11 SQCSCRGTYVDCDSRRLASVPAGIPTNVQILNLYNNQ----------------------- 47
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
I+ LEP + +L L+ L L N+L L F + LT L L N + + N F K
Sbjct 48 -ITNLEPGVFDRLVNLQKLYLSGNQLQALPVGVFDKLSQLTFLSLDENKLTALPNGVFDK 106
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELS 205
L L+L+ N L++ G +L +L+ELL+ NK+ L I + L L L
Sbjct 107 LTELTYLNLNTNQLTALPEGVFDRLVHLKELLMCCNKLTELPR---GIERLTHLTHLALD 163
Query 206 SNQIKEFSPGCFHAIGRLFGLFL 228
NQ+K G F + L +L
Sbjct 164 QNQLKSIPHGAFDRLSSLTHAYL 186
Score = 36.6 bits (83), Expect = 0.80, Method: Compositional matrix adjust.
Identities = 27/79 (34%), Positives = 40/79 (51%), Gaps = 4/79 (5%)
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
+++ ILNL +N + VF L L+ + L N L LP VF+ L L+L +N
Sbjct 36 TNVQILNLYNNQITNLEPGVFDRLVNLQKLYLSGNQLQALPVGVFDKLSQLTFLSLDENK 95
Query 622 ITSVEKKVFGPAFRNLTEL 640
+T++ VF LTEL
Sbjct 96 LTALPNGVFD----KLTEL 110
Score = 35.8 bits (81), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 58/115 (50%), Gaps = 5/115 (4%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
LN+ +N I ++ +F L+NL+ L LS + L+ L F L S L L+L +NK+
Sbjct 41 LNLYNNQITNLEPGVFDRLVNLQKLYLSGN--QLQALPVGVFDKL--SQLTFLSLDENKL 96
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
+ + + F L L L+L N++ G R L ++ E+ + NK +L R
Sbjct 97 TALPNGVFDKLTELTYLNLNTNQLTALPEGVFDR-LVHLKELLMCCNKLTELPRG 150
>6v9u_B B Toll-like receptor 8
Length=811
Score = 73.2 bits (178), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 191/806 (24%), Positives = 298/806 (37%), Gaps = 194/806 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGL-------SSTKLGTQVQLEN-------------------- 172
+ NL L L+ N ++ + G L N
Sbjct 141 KEGISRLINLKNLYLAWNCYFNXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS 200
Query 173 -LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 201 SLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----C 248
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV 289
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 249 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA 306
Query 290 GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 307 SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL----- 360
Query 344 PKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL---------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 -REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXXX 419
Query 387 -----------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
SN + R L + + L+L+ N I I
Sbjct 420 XXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFIG 475
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPS 481
+ F L + L+L N Q L+G E+ + ++ KYL LT N F +
Sbjct 476 PNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASA 527
Query 482 LQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLE 530
L L V + V Q NL +L+LS+NNI + D LE
Sbjct 528 LTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKS 587
Query 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLF 586
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 588 LVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLT 645
Query 587 ELKIID---------------------------------------------LGLNNLNTL 601
EL I D L N ++ L
Sbjct 646 ELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHL 705
Query 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNW 660
P+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W
Sbjct 706 PSGFLSEVSSLKHLDLSSNLLKTINKSALXXXXXTKLSMLELHGNPFECTCD-IGDFRRW 764
Query 661 INE-THTNIPELSSHYLCNTPPHYHG 685
++E + IP L +C +P G
Sbjct 765 MDEHLNVKIPRLVD-VICASPGDQRG 789
>7rc9_B B Toll-like receptor 8
Length=811
Score = 73.2 bits (178), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 191/806 (24%), Positives = 298/806 (37%), Gaps = 194/806 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGL-------SSTKLGTQVQLEN-------------------- 172
+ NL L L+ N ++ + G L N
Sbjct 141 KEGISRLINLKNLYLAWNCYFNXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS 200
Query 173 -LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 201 SLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----C 248
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV 289
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 249 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA 306
Query 290 GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 307 SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL----- 360
Query 344 PKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL---------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 -REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKXXXXXX 419
Query 387 -----------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
SN + R L + + L+L+ N I I
Sbjct 420 XXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFIG 475
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPS 481
+ F L + L+L N Q L+G E+ + ++ KYL LT N F +
Sbjct 476 PNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASA 527
Query 482 LQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLE 530
L L V + V Q NL +L+LS+NNI + D LE
Sbjct 528 LTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKS 587
Query 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLF 586
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 588 LVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLT 645
Query 587 ELKIID---------------------------------------------LGLNNLNTL 601
EL I D L N ++ L
Sbjct 646 ELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHL 705
Query 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNW 660
P+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W
Sbjct 706 PSGFLSEVSSLKHLDLSSNLLKTINKSALXXXXXTKLSMLELHGNPFECTCD-IGDFRRW 764
Query 661 INE-THTNIPELSSHYLCNTPPHYHG 685
++E + IP L +C +P G
Sbjct 765 MDEHLNVKIPRLVD-VICASPGDQRG 789
>7rc9_A A Toll-like receptor 8
Length=811
Score = 73.2 bits (178), Expect = 9e-12, Method: Compositional matrix adjust.
Identities = 191/806 (24%), Positives = 298/806 (37%), Gaps = 194/806 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGL-------SSTKLGTQVQLEN-------------------- 172
+ NL L L+ N ++ + G L N
Sbjct 141 KEGISRLINLKNLYLAWNCYFNXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS 200
Query 173 -LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 201 SLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----C 248
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV 289
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 249 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA 306
Query 290 GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 307 SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL----- 360
Query 344 PKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL---------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 -REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKXXXXXX 419
Query 387 -----------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
SN + R L + + L+L+ N I I
Sbjct 420 XXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFIG 475
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPS 481
+ F L + L+L N Q L+G E+ + ++ KYL LT N F +
Sbjct 476 PNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASA 527
Query 482 LQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLE 530
L L V + V Q NL +L+LS+NNI + D LE
Sbjct 528 LTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKS 587
Query 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLF 586
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 588 LVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLT 645
Query 587 ELKIID---------------------------------------------LGLNNLNTL 601
EL I D L N ++ L
Sbjct 646 ELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHL 705
Query 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNW 660
P+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W
Sbjct 706 PSGFLSEVSSLKHLDLSSNLLKTINKSALXXXXXTKLSMLELHGNPFECTCD-IGDFRRW 764
Query 661 INE-THTNIPELSSHYLCNTPPHYHG 685
++E + IP L +C +P G
Sbjct 765 MDEHLNVKIPRLVD-VICASPGDQRG 789
>6bxa_A A Toll-like receptor 5b, Variable lymphocyte receptor
B chimera
Length=455
Score = 72.0 bits (175), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 99/399 (25%), Positives = 167/399 (42%), Gaps = 67/399 (17%)
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKID 347
V+ N++F L L L+YN L + + +GL N+ L L + ++ +
Sbjct 69 VIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNF---- 124
Query 348 DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHS 407
F+ L LE L + DN+I I+ F F ++R
Sbjct 125 ---FKPLTSLEMLVLRDNNIKKIQPASF--------------FLNMRRF----------- 156
Query 408 PLHILNLTKNKISKI-ESDAFSWLG-HLEVLDLG------LNE--IGQELTGQEWRGLEN 457
H+L+LT NK+ I E D ++ G H +L L +NE +G E G ++ +
Sbjct 157 --HVLDLTFNKVKSICEEDLLNFQGKHFTLLRLSSITLQDMNEYWLGWEKCGNPFKN-TS 213
Query 458 IFEIYLSYNKYLQ-LTRNSFALVPS--LQRLMLRRVALKNVDSSPSPFQPLRNLTI---- 510
I + LS N + + + + F + +Q L+L + F+ N T
Sbjct 214 ITTLDLSGNGFKESMAKRFFDAIAGTKIQSLILSNSYNMGSSFGHTNFKDPDNFTFKGLE 273
Query 511 ------LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
DLS + I + + LE L L N + ++ +A GL+HL
Sbjct 274 ASGVKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNA--------FWGLTHL 325
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
LNL N I +F++L +L+++DL N++ L F +LK L L N + S
Sbjct 326 LKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQLKS 385
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
V +F +L ++ + NP+DC+C I + W+N+
Sbjct 386 VPDGIF-DRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 423
Score = 68.9 bits (167), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 101/388 (26%), Positives = 164/388 (42%), Gaps = 44/388 (11%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+V A C + L QVP+ LP ++ ++L+ N + L +F+R D+ F
Sbjct 7 ECSVIGYNAICINRGLHQVPE-LPAHVNYVDLSLNSIAELNETSFSRLQ-----DLQFLK 60
Query 87 ISKLEPELC------QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--I 138
+ + P L + L L +L L +N+ QL F NL L L ++ +
Sbjct 61 VEQQTPGLVIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVL 120
Query 139 KNNPFVKQKNLITLDLSHNGLSSTKLGTQ-VQLENLQELLLSNNKIQALKSEELDIFANS 197
N F +L L L N + + + + + L L+ NK++++ E+L F
Sbjct 121 SGNFFKPLTSLEMLVLRDNNIKKIQPASFFLNMRRFHVLDLTFNKVKSICEEDLLNFQGK 180
Query 198 SLKKLELSS---NQIKEFSPGCFHAIGRLFG------LFLNNVQLGPSLTEKLCLELANT 248
L LSS + E+ G + G F L L+ S+ ++ +A T
Sbjct 181 HFTLLRLSSITLQDMNEYWLG-WEKCGNPFKNTSITTLDLSGNGFKESMAKRFFDAIAGT 239
Query 249 SIRNLSLSNS----------QLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLP 298
I++L LSNS N TF GL+ + + DLS + + + F+
Sbjct 240 KIQSLILSNSYNMGSSFGHTNFKDPDNFTFKGLEASGVKTCDLSKSKIFALLKSVFSHFT 299
Query 299 QLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLE 358
LE L N I + ++ GL ++ LNL ++F L ID F+ L LE
Sbjct 300 DLEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNF---------LGSIDSRMFENLDKLE 350
Query 359 HLNMEDNDIPGIKSNMFTGLINLKYLSL 386
L++ N I + F GL NLK L+L
Sbjct 351 VLDLSYNHIRALGDQSFLGLPNLKELAL 378
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
Query 408 PLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSY 465
P H+ ++L+ N I+++ +FS L L+ L + G + +RGL ++ + L Y
Sbjct 29 PAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQTPGLVIRNNTFRGLSSLIILKLDY 88
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN-DD 524
N++LQL +F + +L+ L L + L S + F+PL +L +L L +NNI I
Sbjct 89 NQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFFKPLTSLEMLVLRDNNIKKIQPAS 148
Query 525 MLEGLEKLEILDLQHNNLARL 545
+ + +LDL N + +
Sbjct 149 FFLNMRRFHVLDLTFNKVKSI 169
Score = 50.4 bits (119), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 42/128 (33%), Positives = 64/128 (50%), Gaps = 2/128 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K +L +++ L F+ T+L +L L N I KI +N F +L+ L+LS N L
Sbjct 277 VKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLG 336
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAI 220
S L+ L+ L LS N I+AL + N LK+L L +NQ+K G F +
Sbjct 337 SIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPN--LKELALDTNQLKSVPDGIFDRL 394
Query 221 GRLFGLFL 228
L ++L
Sbjct 395 TSLQKIWL 402
Score = 42.0 bits (97), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 33/107 (31%), Positives = 58/107 (54%), Gaps = 2/107 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
L+ L L NE++++ D F T+L +L+L N + I + F L LDLS+N +
Sbjct 301 LEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIR 360
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+ + + L NL+EL L N+++++ D +SL+K+ L +N
Sbjct 361 ALGDQSFLGLPNLKELALDTNQLKSVPDGIFDRL--TSLQKIWLHTN 405
Score = 37.7 bits (86), Expect = 0.65, Method: Compositional matrix adjust.
Identities = 27/83 (33%), Positives = 42/83 (51%), Gaps = 0/83 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T++ LNL+ N L + + F +L LD+ +N I L + LP LK L L N+
Sbjct 323 THLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQ 382
Query 111 LSQLSDKTFAFCTNLTELHLMSN 133
L + D F T+L ++ L +N
Sbjct 383 LKSVPDGIFDRLTSLQKIWLHTN 405
>5wyz_B B Toll-like receptor 8
Length=811
Score = 72.8 bits (177), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 194/805 (24%), Positives = 302/805 (38%), Gaps = 192/805 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
+ DDF L L +N+ N I I +F NL+ + LS + S L +T
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRIS--PLVKDTX 416
Query 402 VSL---------------------AHS-------PL---------HILNLTKNKISKIES 424
HS PL L+L+ N I I
Sbjct 417 XXXXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGP 476
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSL 482
+ F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 477 NQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASAL 528
Query 483 QRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEK 531
L V + V Q NL +L+LS+NNI + D LE
Sbjct 529 TELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSL 588
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFE 587
+E++ N L LW + + I KGL +L L+L N IP E F L E
Sbjct 589 VELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTE 646
Query 588 LKIID---------------------------------------------LGLNNLNTLP 602
L I D L N ++ LP
Sbjct 647 LHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLP 706
Query 603 ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNWI 661
+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W+
Sbjct 707 SGFLSEVSSLKHLDLSSNLLKTINKXXXXXXXXTKLSMLELHGNPFECTCD-IGDFRRWM 765
Query 662 NE-THTNIPELSSHYLCNTPPHYHG 685
+E + IP L +C +P G
Sbjct 766 DEHLNVKIPRLVD-VICASPGDQRG 789
>5gy2_A A Tlr5b protein,Variable lymphocyte receptor B
Length=455
Score = 72.0 bits (175), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 99/399 (25%), Positives = 167/399 (42%), Gaps = 67/399 (17%)
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKID 347
V+ N++F L L L+YN L + + +GL N+ L L + ++ +
Sbjct 69 VIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNF---- 124
Query 348 DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHS 407
F+ L LE L + DN+I I+ F F ++R
Sbjct 125 ---FKPLTSLEMLVLRDNNIKKIQPASF--------------FLNMRRF----------- 156
Query 408 PLHILNLTKNKISKI-ESDAFSWLG-HLEVLDLG------LNE--IGQELTGQEWRGLEN 457
H+L+LT NK+ I E D ++ G H +L L +NE +G E G ++ +
Sbjct 157 --HVLDLTFNKVKSICEEDLLNFQGKHFTLLRLSSITLQDMNEYWLGWEKCGNPFKN-TS 213
Query 458 IFEIYLSYNKYLQ-LTRNSFALVPS--LQRLMLRRVALKNVDSSPSPFQPLRNLTI---- 510
I + LS N + + + + F + +Q L+L + F+ N T
Sbjct 214 ITTLDLSGNGFKESMAKRFFDAIAGTKIQSLILSNSYNMGSSFGHTNFKDPDNFTFKGLE 273
Query 511 ------LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
DLS + I + + LE L L N + ++ +A GL+HL
Sbjct 274 ASGVKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNA--------FWGLTHL 325
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
LNL N I +F++L +L+++DL N++ L F +LK L L N + S
Sbjct 326 LKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQLKS 385
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
V +F +L ++ + NP+DC+C I + W+N+
Sbjct 386 VPDGIF-DRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 423
Score = 69.7 bits (169), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 101/384 (26%), Positives = 163/384 (42%), Gaps = 34/384 (9%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+V A C + L QVP+ LP ++ ++L+ N + L +F+R L L V
Sbjct 6 SECSVIGYNAICINRGLHQVPE-LPAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQ 64
Query 86 TIS-KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNP 142
T + + L L +L L +N+ QL F NL L L ++ + N
Sbjct 65 TPGLVIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNF 124
Query 143 FVKQKNLITLDLSHNGLSSTKLGTQ-VQLENLQELLLSNNKIQALKSEELDIFANSSLKK 201
F +L L L N + + + + + L L+ NK++++ E+L F
Sbjct 125 FKPLTSLEMLVLRDNNIKKIQPASFFLNMRRFHVLDLTFNKVKSICEEDLLNFQGKHFTL 184
Query 202 LELSS---NQIKEFSPGCFHAIGRLFG------LFLNNVQLGPSLTEKLCLELANTSIRN 252
L LSS + E+ G + G F L L+ S+ ++ +A T I++
Sbjct 185 LRLSSITLQDMNEYWLG-WEKCGNPFKNTSITTLDLSGNGFKESMAKRFFDAIAGTKIQS 243
Query 253 LSLSNS----------QLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
L LSNS N TF GL+ + + DLS + + + F+ LE
Sbjct 244 LILSNSYNMGSSFGHTNFKDPDNFTFKGLEASGVKTCDLSKSKIFALLKSVFSHFTDLEQ 303
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
L N I + ++ GL ++ LNL ++F L ID F+ L LE L++
Sbjct 304 LTLAQNEINKIDDNAFWGLTHLLKLNLSQNF---------LGSIDSRMFENLDKLEVLDL 354
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N I + F GL NLK L+L
Sbjct 355 SYNHIRALGDQSFLGLPNLKELAL 378
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
Query 408 PLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSY 465
P H+ ++L+ N I+++ +FS L L+ L + G + +RGL ++ + L Y
Sbjct 29 PAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQTPGLVIRNNTFRGLSSLIILKLDY 88
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN-DD 524
N++LQL +F + +L+ L L + L S + F+PL +L +L L +NNI I
Sbjct 89 NQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFFKPLTSLEMLVLRDNNIKKIQPAS 148
Query 525 MLEGLEKLEILDLQHNNLARL 545
+ + +LDL N + +
Sbjct 149 FFLNMRRFHVLDLTFNKVKSI 169
Score = 50.4 bits (119), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 42/128 (33%), Positives = 64/128 (50%), Gaps = 2/128 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K +L +++ L F+ T+L +L L N I KI +N F +L+ L+LS N L
Sbjct 277 VKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLG 336
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAI 220
S L+ L+ L LS N I+AL + N LK+L L +NQ+K G F +
Sbjct 337 SIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPN--LKELALDTNQLKSVPDGIFDRL 394
Query 221 GRLFGLFL 228
L ++L
Sbjct 395 TSLQKIWL 402
Score = 42.0 bits (97), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 33/107 (31%), Positives = 58/107 (54%), Gaps = 2/107 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
L+ L L NE++++ D F T+L +L+L N + I + F L LDLS+N +
Sbjct 301 LEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIR 360
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+ + + L NL+EL L N+++++ D +SL+K+ L +N
Sbjct 361 ALGDQSFLGLPNLKELALDTNQLKSVPDGIFDRL--TSLQKIWLHTN 405
Score = 37.7 bits (86), Expect = 0.63, Method: Compositional matrix adjust.
Identities = 27/83 (33%), Positives = 42/83 (51%), Gaps = 0/83 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T++ LNL+ N L + + F +L LD+ +N I L + LP LK L L N+
Sbjct 323 THLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQ 382
Query 111 LSQLSDKTFAFCTNLTELHLMSN 133
L + D F T+L ++ L +N
Sbjct 383 LKSVPDGIFDRLTSLQKIWLHTN 405
>6bxc_B B Toll-like receptor 5b, Variable lymphocyte receptor
B chimera
Length=455
Score = 72.0 bits (175), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 99/399 (25%), Positives = 167/399 (42%), Gaps = 67/399 (17%)
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKID 347
V+ N++F L L L+YN L + + +GL N+ L L + ++ +
Sbjct 69 VIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNF---- 124
Query 348 DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHS 407
F+ L LE L + DN+I I+ F F ++R
Sbjct 125 ---FKPLTSLEMLVLRDNNIKKIQPASF--------------FLNMRRF----------- 156
Query 408 PLHILNLTKNKISKI-ESDAFSWLG-HLEVLDLG------LNE--IGQELTGQEWRGLEN 457
H+L+LT NK+ I E D ++ G H +L L +NE +G E G ++ +
Sbjct 157 --HVLDLTFNKVKSICEEDLLNFQGKHFTLLRLSSITLQDMNEYWLGWEKCGNPFKN-TS 213
Query 458 IFEIYLSYNKYLQ-LTRNSFALVPS--LQRLMLRRVALKNVDSSPSPFQPLRNLTI---- 510
I + LS N + + + + F + +Q L+L + F+ N T
Sbjct 214 ITTLDLSGNGFKESMAKRFFDAIAGTKIQSLILSNSYNMGSSFGHTNFKDPDNFTFKGLE 273
Query 511 ------LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
DLS + I + + LE L L N + ++ +A GL+HL
Sbjct 274 ASGVKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNA--------FWGLTHL 325
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
LNL N I +F++L +L+++DL N++ L F +LK L L N + S
Sbjct 326 LKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQLKS 385
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
V +F +L ++ + NP+DC+C I + W+N+
Sbjct 386 VPDGIF-DRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 423
Score = 69.3 bits (168), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 101/383 (26%), Positives = 162/383 (42%), Gaps = 34/383 (9%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+V A C + L QVP+ LP ++ ++L+ N + L +F+R L L V T
Sbjct 7 ECSVIGYNAICINRGLHQVPE-LPAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQT 65
Query 87 IS-KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPF 143
+ + L L +L L +N+ QL F NL L L ++ + N F
Sbjct 66 PGLVIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFF 125
Query 144 VKQKNLITLDLSHNGLSSTKLGTQ-VQLENLQELLLSNNKIQALKSEELDIFANSSLKKL 202
+L L L N + + + + + L L+ NK++++ E+L F L
Sbjct 126 KPLTSLEMLVLRDNNIKKIQPASFFLNMRRFHVLDLTFNKVKSICEEDLLNFQGKHFTLL 185
Query 203 ELSS---NQIKEFSPGCFHAIGRLFG------LFLNNVQLGPSLTEKLCLELANTSIRNL 253
LSS + E+ G + G F L L+ S+ ++ +A T I++L
Sbjct 186 RLSSITLQDMNEYWLG-WEKCGNPFKNTSITTLDLSGNGFKESMAKRFFDAIAGTKIQSL 244
Query 254 SLSNS----------QLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYF 303
LSNS N TF GL+ + + DLS + + + F+ LE
Sbjct 245 ILSNSYNMGSSFGHTNFKDPDNFTFKGLEASGVKTCDLSKSKIFALLKSVFSHFTDLEQL 304
Query 304 FLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNME 363
L N I + ++ GL ++ LNL ++F L ID F+ L LE L++
Sbjct 305 TLAQNEINKIDDNAFWGLTHLLKLNLSQNF---------LGSIDSRMFENLDKLEVLDLS 355
Query 364 DNDIPGIKSNMFTGLINLKYLSL 386
N I + F GL NLK L+L
Sbjct 356 YNHIRALGDQSFLGLPNLKELAL 378
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
Query 408 PLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSY 465
P H+ ++L+ N I+++ +FS L L+ L + G + +RGL ++ + L Y
Sbjct 29 PAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQTPGLVIRNNTFRGLSSLIILKLDY 88
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN-DD 524
N++LQL +F + +L+ L L + L S + F+PL +L +L L +NNI I
Sbjct 89 NQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFFKPLTSLEMLVLRDNNIKKIQPAS 148
Query 525 MLEGLEKLEILDLQHNNLARL 545
+ + +LDL N + +
Sbjct 149 FFLNMRRFHVLDLTFNKVKSI 169
Score = 50.4 bits (119), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 42/128 (33%), Positives = 64/128 (50%), Gaps = 2/128 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K +L +++ L F+ T+L +L L N I KI +N F +L+ L+LS N L
Sbjct 277 VKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLG 336
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAI 220
S L+ L+ L LS N I+AL + N LK+L L +NQ+K G F +
Sbjct 337 SIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPN--LKELALDTNQLKSVPDGIFDRL 394
Query 221 GRLFGLFL 228
L ++L
Sbjct 395 TSLQKIWL 402
Score = 42.0 bits (97), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 33/107 (31%), Positives = 58/107 (54%), Gaps = 2/107 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
L+ L L NE++++ D F T+L +L+L N + I + F L LDLS+N +
Sbjct 301 LEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIR 360
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+ + + L NL+EL L N+++++ D +SL+K+ L +N
Sbjct 361 ALGDQSFLGLPNLKELALDTNQLKSVPDGIFDRL--TSLQKIWLHTN 405
Score = 37.7 bits (86), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 27/83 (33%), Positives = 42/83 (51%), Gaps = 0/83 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T++ LNL+ N L + + F +L LD+ +N I L + LP LK L L N+
Sbjct 323 THLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQ 382
Query 111 LSQLSDKTFAFCTNLTELHLMSN 133
L + D F T+L ++ L +N
Sbjct 383 LKSVPDGIFDRLTSLQKIWLHTN 405
>5gy2_C B Tlr5b protein,Variable lymphocyte receptor B
Length=455
Score = 72.0 bits (175), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 99/399 (25%), Positives = 167/399 (42%), Gaps = 67/399 (17%)
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKID 347
V+ N++F L L L+YN L + + +GL N+ L L + ++ +
Sbjct 69 VIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNF---- 124
Query 348 DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHS 407
F+ L LE L + DN+I I+ F F ++R
Sbjct 125 ---FKPLTSLEMLVLRDNNIKKIQPASF--------------FLNMRRF----------- 156
Query 408 PLHILNLTKNKISKI-ESDAFSWLG-HLEVLDLG------LNE--IGQELTGQEWRGLEN 457
H+L+LT NK+ I E D ++ G H +L L +NE +G E G ++ +
Sbjct 157 --HVLDLTFNKVKSICEEDLLNFQGKHFTLLRLSSITLQDMNEYWLGWEKCGNPFKN-TS 213
Query 458 IFEIYLSYNKYLQ-LTRNSFALVPS--LQRLMLRRVALKNVDSSPSPFQPLRNLTI---- 510
I + LS N + + + + F + +Q L+L + F+ N T
Sbjct 214 ITTLDLSGNGFKESMAKRFFDAIAGTKIQSLILSNSYNMGSSFGHTNFKDPDNFTFKGLE 273
Query 511 ------LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
DLS + I + + LE L L N + ++ +A GL+HL
Sbjct 274 ASGVKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNA--------FWGLTHL 325
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
LNL N I +F++L +L+++DL N++ L F +LK L L N + S
Sbjct 326 LKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQLKS 385
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
V +F +L ++ + NP+DC+C I + W+N+
Sbjct 386 VPDGIF-DRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 423
Score = 69.3 bits (168), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 101/383 (26%), Positives = 162/383 (42%), Gaps = 34/383 (9%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+V A C + L QVP+ LP ++ ++L+ N + L +F+R L L V T
Sbjct 7 ECSVIGYNAICINRGLHQVPE-LPAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQT 65
Query 87 IS-KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPF 143
+ + L L +L L +N+ QL F NL L L ++ + N F
Sbjct 66 PGLVIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFF 125
Query 144 VKQKNLITLDLSHNGLSSTKLGTQ-VQLENLQELLLSNNKIQALKSEELDIFANSSLKKL 202
+L L L N + + + + + L L+ NK++++ E+L F L
Sbjct 126 KPLTSLEMLVLRDNNIKKIQPASFFLNMRRFHVLDLTFNKVKSICEEDLLNFQGKHFTLL 185
Query 203 ELSS---NQIKEFSPGCFHAIGRLFG------LFLNNVQLGPSLTEKLCLELANTSIRNL 253
LSS + E+ G + G F L L+ S+ ++ +A T I++L
Sbjct 186 RLSSITLQDMNEYWLG-WEKCGNPFKNTSITTLDLSGNGFKESMAKRFFDAIAGTKIQSL 244
Query 254 SLSNS----------QLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYF 303
LSNS N TF GL+ + + DLS + + + F+ LE
Sbjct 245 ILSNSYNMGSSFGHTNFKDPDNFTFKGLEASGVKTCDLSKSKIFALLKSVFSHFTDLEQL 304
Query 304 FLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNME 363
L N I + ++ GL ++ LNL ++F L ID F+ L LE L++
Sbjct 305 TLAQNEINKIDDNAFWGLTHLLKLNLSQNF---------LGSIDSRMFENLDKLEVLDLS 355
Query 364 DNDIPGIKSNMFTGLINLKYLSL 386
N I + F GL NLK L+L
Sbjct 356 YNHIRALGDQSFLGLPNLKELAL 378
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
Query 408 PLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSY 465
P H+ ++L+ N I+++ +FS L L+ L + G + +RGL ++ + L Y
Sbjct 29 PAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQTPGLVIRNNTFRGLSSLIILKLDY 88
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN-DD 524
N++LQL +F + +L+ L L + L S + F+PL +L +L L +NNI I
Sbjct 89 NQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFFKPLTSLEMLVLRDNNIKKIQPAS 148
Query 525 MLEGLEKLEILDLQHNNLARL 545
+ + +LDL N + +
Sbjct 149 FFLNMRRFHVLDLTFNKVKSI 169
Score = 50.4 bits (119), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 42/128 (33%), Positives = 64/128 (50%), Gaps = 2/128 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K +L +++ L F+ T+L +L L N I KI +N F +L+ L+LS N L
Sbjct 277 VKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLG 336
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAI 220
S L+ L+ L LS N I+AL + N LK+L L +NQ+K G F +
Sbjct 337 SIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPN--LKELALDTNQLKSVPDGIFDRL 394
Query 221 GRLFGLFL 228
L ++L
Sbjct 395 TSLQKIWL 402
Score = 42.0 bits (97), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 33/107 (31%), Positives = 58/107 (54%), Gaps = 2/107 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
L+ L L NE++++ D F T+L +L+L N + I + F L LDLS+N +
Sbjct 301 LEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIR 360
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+ + + L NL+EL L N+++++ D +SL+K+ L +N
Sbjct 361 ALGDQSFLGLPNLKELALDTNQLKSVPDGIFDRL--TSLQKIWLHTN 405
Score = 37.7 bits (86), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 27/83 (33%), Positives = 42/83 (51%), Gaps = 0/83 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T++ LNL+ N L + + F +L LD+ +N I L + LP LK L L N+
Sbjct 323 THLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQ 382
Query 111 LSQLSDKTFAFCTNLTELHLMSN 133
L + D F T+L ++ L +N
Sbjct 383 LKSVPDGIFDRLTSLQKIWLHTN 405
>3v47_A A Toll-like receptor 5b and variable lymphocyte receptor
B.61 chimeric protein
Length=455
Score = 72.0 bits (175), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 99/399 (25%), Positives = 167/399 (42%), Gaps = 67/399 (17%)
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKID 347
V+ N++F L L L+YN L + + +GL N+ L L + ++ +
Sbjct 69 VIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNF---- 124
Query 348 DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHS 407
F+ L LE L + DN+I I+ F F ++R
Sbjct 125 ---FKPLTSLEMLVLRDNNIKKIQPASF--------------FLNMRRF----------- 156
Query 408 PLHILNLTKNKISKI-ESDAFSWLG-HLEVLDLG------LNE--IGQELTGQEWRGLEN 457
H+L+LT NK+ I E D ++ G H +L L +NE +G E G ++ +
Sbjct 157 --HVLDLTFNKVKSICEEDLLNFQGKHFTLLRLSSITLQDMNEYWLGWEKCGNPFKN-TS 213
Query 458 IFEIYLSYNKYLQ-LTRNSFALVPS--LQRLMLRRVALKNVDSSPSPFQPLRNLTI---- 510
I + LS N + + + + F + +Q L+L + F+ N T
Sbjct 214 ITTLDLSGNGFKESMAKRFFDAIAGTKIQSLILSNSYNMGSSFGHTNFKDPDNFTFKGLE 273
Query 511 ------LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
DLS + I + + LE L L N + ++ +A GL+HL
Sbjct 274 ASGVKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNA--------FWGLTHL 325
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
LNL N I +F++L +L+++DL N++ L F +LK L L N + S
Sbjct 326 LKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQLKS 385
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
V +F +L ++ + NP+DC+C I + W+N+
Sbjct 386 VPDGIF-DRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 423
Score = 69.3 bits (168), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 101/383 (26%), Positives = 162/383 (42%), Gaps = 34/383 (9%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+V A C + L QVP+ LP ++ ++L+ N + L +F+R L L V T
Sbjct 7 ECSVIGYNAICINRGLHQVPE-LPAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQT 65
Query 87 IS-KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPF 143
+ + L L +L L +N+ QL F NL L L ++ + N F
Sbjct 66 PGLVIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFF 125
Query 144 VKQKNLITLDLSHNGLSSTKLGTQ-VQLENLQELLLSNNKIQALKSEELDIFANSSLKKL 202
+L L L N + + + + + L L+ NK++++ E+L F L
Sbjct 126 KPLTSLEMLVLRDNNIKKIQPASFFLNMRRFHVLDLTFNKVKSICEEDLLNFQGKHFTLL 185
Query 203 ELSS---NQIKEFSPGCFHAIGRLFG------LFLNNVQLGPSLTEKLCLELANTSIRNL 253
LSS + E+ G + G F L L+ S+ ++ +A T I++L
Sbjct 186 RLSSITLQDMNEYWLG-WEKCGNPFKNTSITTLDLSGNGFKESMAKRFFDAIAGTKIQSL 244
Query 254 SLSNS----------QLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYF 303
LSNS N TF GL+ + + DLS + + + F+ LE
Sbjct 245 ILSNSYNMGSSFGHTNFKDPDNFTFKGLEASGVKTCDLSKSKIFALLKSVFSHFTDLEQL 304
Query 304 FLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNME 363
L N I + ++ GL ++ LNL ++F L ID F+ L LE L++
Sbjct 305 TLAQNEINKIDDNAFWGLTHLLKLNLSQNF---------LGSIDSRMFENLDKLEVLDLS 355
Query 364 DNDIPGIKSNMFTGLINLKYLSL 386
N I + F GL NLK L+L
Sbjct 356 YNHIRALGDQSFLGLPNLKELAL 378
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
Query 408 PLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSY 465
P H+ ++L+ N I+++ +FS L L+ L + G + +RGL ++ + L Y
Sbjct 29 PAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQTPGLVIRNNTFRGLSSLIILKLDY 88
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN-DD 524
N++LQL +F + +L+ L L + L S + F+PL +L +L L +NNI I
Sbjct 89 NQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFFKPLTSLEMLVLRDNNIKKIQPAS 148
Query 525 MLEGLEKLEILDLQHNNLARL 545
+ + +LDL N + +
Sbjct 149 FFLNMRRFHVLDLTFNKVKSI 169
Score = 50.4 bits (119), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 42/128 (33%), Positives = 64/128 (50%), Gaps = 2/128 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K +L +++ L F+ T+L +L L N I KI +N F +L+ L+LS N L
Sbjct 277 VKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLG 336
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAI 220
S L+ L+ L LS N I+AL + N LK+L L +NQ+K G F +
Sbjct 337 SIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPN--LKELALDTNQLKSVPDGIFDRL 394
Query 221 GRLFGLFL 228
L ++L
Sbjct 395 TSLQKIWL 402
Score = 42.0 bits (97), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 33/107 (31%), Positives = 58/107 (54%), Gaps = 2/107 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
L+ L L NE++++ D F T+L +L+L N + I + F L LDLS+N +
Sbjct 301 LEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIR 360
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+ + + L NL+EL L N+++++ D +SL+K+ L +N
Sbjct 361 ALGDQSFLGLPNLKELALDTNQLKSVPDGIFDRL--TSLQKIWLHTN 405
Score = 37.7 bits (86), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 27/83 (33%), Positives = 42/83 (51%), Gaps = 0/83 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T++ LNL+ N L + + F +L LD+ +N I L + LP LK L L N+
Sbjct 323 THLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQ 382
Query 111 LSQLSDKTFAFCTNLTELHLMSN 133
L + D F T+L ++ L +N
Sbjct 383 LKSVPDGIFDRLTSLQKIWLHTN 405
>6bxa_B B Toll-like receptor 5b, Variable lymphocyte receptor
B chimera
Length=455
Score = 72.0 bits (175), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 99/399 (25%), Positives = 167/399 (42%), Gaps = 67/399 (17%)
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKID 347
V+ N++F L L L+YN L + + +GL N+ L L + ++ +
Sbjct 69 VIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNF---- 124
Query 348 DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHS 407
F+ L LE L + DN+I I+ F F ++R
Sbjct 125 ---FKPLTSLEMLVLRDNNIKKIQPASF--------------FLNMRRF----------- 156
Query 408 PLHILNLTKNKISKI-ESDAFSWLG-HLEVLDLG------LNE--IGQELTGQEWRGLEN 457
H+L+LT NK+ I E D ++ G H +L L +NE +G E G ++ +
Sbjct 157 --HVLDLTFNKVKSICEEDLLNFQGKHFTLLRLSSITLQDMNEYWLGWEKCGNPFKN-TS 213
Query 458 IFEIYLSYNKYLQ-LTRNSFALVPS--LQRLMLRRVALKNVDSSPSPFQPLRNLTI---- 510
I + LS N + + + + F + +Q L+L + F+ N T
Sbjct 214 ITTLDLSGNGFKESMAKRFFDAIAGTKIQSLILSNSYNMGSSFGHTNFKDPDNFTFKGLE 273
Query 511 ------LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
DLS + I + + LE L L N + ++ +A GL+HL
Sbjct 274 ASGVKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNA--------FWGLTHL 325
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
LNL N I +F++L +L+++DL N++ L F +LK L L N + S
Sbjct 326 LKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQLKS 385
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
V +F +L ++ + NP+DC+C I + W+N+
Sbjct 386 VPDGIF-DRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 423
Score = 69.3 bits (168), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 101/383 (26%), Positives = 162/383 (42%), Gaps = 34/383 (9%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+V A C + L QVP+ LP ++ ++L+ N + L +F+R L L V T
Sbjct 7 ECSVIGYNAICINRGLHQVPE-LPAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQT 65
Query 87 IS-KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPF 143
+ + L L +L L +N+ QL F NL L L ++ + N F
Sbjct 66 PGLVIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFF 125
Query 144 VKQKNLITLDLSHNGLSSTKLGTQ-VQLENLQELLLSNNKIQALKSEELDIFANSSLKKL 202
+L L L N + + + + + L L+ NK++++ E+L F L
Sbjct 126 KPLTSLEMLVLRDNNIKKIQPASFFLNMRRFHVLDLTFNKVKSICEEDLLNFQGKHFTLL 185
Query 203 ELSS---NQIKEFSPGCFHAIGRLFG------LFLNNVQLGPSLTEKLCLELANTSIRNL 253
LSS + E+ G + G F L L+ S+ ++ +A T I++L
Sbjct 186 RLSSITLQDMNEYWLG-WEKCGNPFKNTSITTLDLSGNGFKESMAKRFFDAIAGTKIQSL 244
Query 254 SLSNS----------QLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYF 303
LSNS N TF GL+ + + DLS + + + F+ LE
Sbjct 245 ILSNSYNMGSSFGHTNFKDPDNFTFKGLEASGVKTCDLSKSKIFALLKSVFSHFTDLEQL 304
Query 304 FLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNME 363
L N I + ++ GL ++ LNL ++F L ID F+ L LE L++
Sbjct 305 TLAQNEINKIDDNAFWGLTHLLKLNLSQNF---------LGSIDSRMFENLDKLEVLDLS 355
Query 364 DNDIPGIKSNMFTGLINLKYLSL 386
N I + F GL NLK L+L
Sbjct 356 YNHIRALGDQSFLGLPNLKELAL 378
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
Query 408 PLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSY 465
P H+ ++L+ N I+++ +FS L L+ L + G + +RGL ++ + L Y
Sbjct 29 PAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQTPGLVIRNNTFRGLSSLIILKLDY 88
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN-DD 524
N++LQL +F + +L+ L L + L S + F+PL +L +L L +NNI I
Sbjct 89 NQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFFKPLTSLEMLVLRDNNIKKIQPAS 148
Query 525 MLEGLEKLEILDLQHNNLARL 545
+ + +LDL N + +
Sbjct 149 FFLNMRRFHVLDLTFNKVKSI 169
Score = 50.4 bits (119), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 42/128 (33%), Positives = 64/128 (50%), Gaps = 2/128 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K +L +++ L F+ T+L +L L N I KI +N F +L+ L+LS N L
Sbjct 277 VKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLG 336
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAI 220
S L+ L+ L LS N I+AL + N LK+L L +NQ+K G F +
Sbjct 337 SIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPN--LKELALDTNQLKSVPDGIFDRL 394
Query 221 GRLFGLFL 228
L ++L
Sbjct 395 TSLQKIWL 402
Score = 42.0 bits (97), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 33/107 (31%), Positives = 58/107 (54%), Gaps = 2/107 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
L+ L L NE++++ D F T+L +L+L N + I + F L LDLS+N +
Sbjct 301 LEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIR 360
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+ + + L NL+EL L N+++++ D +SL+K+ L +N
Sbjct 361 ALGDQSFLGLPNLKELALDTNQLKSVPDGIFDRL--TSLQKIWLHTN 405
Score = 37.7 bits (86), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 27/83 (33%), Positives = 42/83 (51%), Gaps = 0/83 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T++ LNL+ N L + + F +L LD+ +N I L + LP LK L L N+
Sbjct 323 THLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQ 382
Query 111 LSQLSDKTFAFCTNLTELHLMSN 133
L + D F T+L ++ L +N
Sbjct 383 LKSVPDGIFDRLTSLQKIWLHTN 405
>6bxc_A A Toll-like receptor 5b, Variable lymphocyte receptor
B chimera
Length=455
Score = 72.0 bits (175), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 99/399 (25%), Positives = 167/399 (42%), Gaps = 67/399 (17%)
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKID 347
V+ N++F L L L+YN L + + +GL N+ L L + ++ +
Sbjct 69 VIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNF---- 124
Query 348 DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHS 407
F+ L LE L + DN+I I+ F F ++R
Sbjct 125 ---FKPLTSLEMLVLRDNNIKKIQPASF--------------FLNMRRF----------- 156
Query 408 PLHILNLTKNKISKI-ESDAFSWLG-HLEVLDLG------LNE--IGQELTGQEWRGLEN 457
H+L+LT NK+ I E D ++ G H +L L +NE +G E G ++ +
Sbjct 157 --HVLDLTFNKVKSICEEDLLNFQGKHFTLLRLSSITLQDMNEYWLGWEKCGNPFKN-TS 213
Query 458 IFEIYLSYNKYLQ-LTRNSFALVPS--LQRLMLRRVALKNVDSSPSPFQPLRNLTI---- 510
I + LS N + + + + F + +Q L+L + F+ N T
Sbjct 214 ITTLDLSGNGFKESMAKRFFDAIAGTKIQSLILSNSYNMGSSFGHTNFKDPDNFTFKGLE 273
Query 511 ------LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
DLS + I + + LE L L N + ++ +A GL+HL
Sbjct 274 ASGVKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNA--------FWGLTHL 325
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
LNL N I +F++L +L+++DL N++ L F +LK L L N + S
Sbjct 326 LKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQLKS 385
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
V +F +L ++ + NP+DC+C I + W+N+
Sbjct 386 VPDGIF-DRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 423
Score = 69.3 bits (168), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 101/383 (26%), Positives = 162/383 (42%), Gaps = 34/383 (9%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+V A C + L QVP+ LP ++ ++L+ N + L +F+R L L V T
Sbjct 7 ECSVIGYNAICINRGLHQVPE-LPAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQT 65
Query 87 IS-KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPF 143
+ + L L +L L +N+ QL F NL L L ++ + N F
Sbjct 66 PGLVIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFF 125
Query 144 VKQKNLITLDLSHNGLSSTKLGTQ-VQLENLQELLLSNNKIQALKSEELDIFANSSLKKL 202
+L L L N + + + + + L L+ NK++++ E+L F L
Sbjct 126 KPLTSLEMLVLRDNNIKKIQPASFFLNMRRFHVLDLTFNKVKSICEEDLLNFQGKHFTLL 185
Query 203 ELSS---NQIKEFSPGCFHAIGRLFG------LFLNNVQLGPSLTEKLCLELANTSIRNL 253
LSS + E+ G + G F L L+ S+ ++ +A T I++L
Sbjct 186 RLSSITLQDMNEYWLG-WEKCGNPFKNTSITTLDLSGNGFKESMAKRFFDAIAGTKIQSL 244
Query 254 SLSNS----------QLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYF 303
LSNS N TF GL+ + + DLS + + + F+ LE
Sbjct 245 ILSNSYNMGSSFGHTNFKDPDNFTFKGLEASGVKTCDLSKSKIFALLKSVFSHFTDLEQL 304
Query 304 FLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNME 363
L N I + ++ GL ++ LNL ++F L ID F+ L LE L++
Sbjct 305 TLAQNEINKIDDNAFWGLTHLLKLNLSQNF---------LGSIDSRMFENLDKLEVLDLS 355
Query 364 DNDIPGIKSNMFTGLINLKYLSL 386
N I + F GL NLK L+L
Sbjct 356 YNHIRALGDQSFLGLPNLKELAL 378
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
Query 408 PLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSY 465
P H+ ++L+ N I+++ +FS L L+ L + G + +RGL ++ + L Y
Sbjct 29 PAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQTPGLVIRNNTFRGLSSLIILKLDY 88
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN-DD 524
N++LQL +F + +L+ L L + L S + F+PL +L +L L +NNI I
Sbjct 89 NQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFFKPLTSLEMLVLRDNNIKKIQPAS 148
Query 525 MLEGLEKLEILDLQHNNLARL 545
+ + +LDL N + +
Sbjct 149 FFLNMRRFHVLDLTFNKVKSI 169
Score = 50.4 bits (119), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 42/128 (33%), Positives = 64/128 (50%), Gaps = 2/128 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K +L +++ L F+ T+L +L L N I KI +N F +L+ L+LS N L
Sbjct 277 VKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLG 336
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAI 220
S L+ L+ L LS N I+AL + N LK+L L +NQ+K G F +
Sbjct 337 SIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPN--LKELALDTNQLKSVPDGIFDRL 394
Query 221 GRLFGLFL 228
L ++L
Sbjct 395 TSLQKIWL 402
Score = 42.0 bits (97), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 33/107 (31%), Positives = 58/107 (54%), Gaps = 2/107 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
L+ L L NE++++ D F T+L +L+L N + I + F L LDLS+N +
Sbjct 301 LEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIR 360
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+ + + L NL+EL L N+++++ D +SL+K+ L +N
Sbjct 361 ALGDQSFLGLPNLKELALDTNQLKSVPDGIFDRL--TSLQKIWLHTN 405
Score = 37.7 bits (86), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 27/83 (33%), Positives = 42/83 (51%), Gaps = 0/83 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T++ LNL+ N L + + F +L LD+ +N I L + LP LK L L N+
Sbjct 323 THLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQ 382
Query 111 LSQLSDKTFAFCTNLTELHLMSN 133
L + D F T+L ++ L +N
Sbjct 383 LKSVPDGIFDRLTSLQKIWLHTN 405
>3v47_B B Toll-like receptor 5b and variable lymphocyte receptor
B.61 chimeric protein
Length=455
Score = 72.0 bits (175), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 99/399 (25%), Positives = 167/399 (42%), Gaps = 67/399 (17%)
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKID 347
V+ N++F L L L+YN L + + +GL N+ L L + ++ +
Sbjct 69 VIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNF---- 124
Query 348 DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHS 407
F+ L LE L + DN+I I+ F F ++R
Sbjct 125 ---FKPLTSLEMLVLRDNNIKKIQPASF--------------FLNMRRF----------- 156
Query 408 PLHILNLTKNKISKI-ESDAFSWLG-HLEVLDLG------LNE--IGQELTGQEWRGLEN 457
H+L+LT NK+ I E D ++ G H +L L +NE +G E G ++ +
Sbjct 157 --HVLDLTFNKVKSICEEDLLNFQGKHFTLLRLSSITLQDMNEYWLGWEKCGNPFKN-TS 213
Query 458 IFEIYLSYNKYLQ-LTRNSFALVPS--LQRLMLRRVALKNVDSSPSPFQPLRNLTI---- 510
I + LS N + + + + F + +Q L+L + F+ N T
Sbjct 214 ITTLDLSGNGFKESMAKRFFDAIAGTKIQSLILSNSYNMGSSFGHTNFKDPDNFTFKGLE 273
Query 511 ------LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
DLS + I + + LE L L N + ++ +A GL+HL
Sbjct 274 ASGVKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNA--------FWGLTHL 325
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
LNL N I +F++L +L+++DL N++ L F +LK L L N + S
Sbjct 326 LKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQLKS 385
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
V +F +L ++ + NP+DC+C I + W+N+
Sbjct 386 VPDGIF-DRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 423
Score = 69.3 bits (168), Expect = 8e-11, Method: Compositional matrix adjust.
Identities = 101/383 (26%), Positives = 162/383 (42%), Gaps = 34/383 (9%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+V A C + L QVP+ LP ++ ++L+ N + L +F+R L L V T
Sbjct 7 ECSVIGYNAICINRGLHQVPE-LPAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQT 65
Query 87 IS-KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPF 143
+ + L L +L L +N+ QL F NL L L ++ + N F
Sbjct 66 PGLVIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFF 125
Query 144 VKQKNLITLDLSHNGLSSTKLGTQ-VQLENLQELLLSNNKIQALKSEELDIFANSSLKKL 202
+L L L N + + + + + L L+ NK++++ E+L F L
Sbjct 126 KPLTSLEMLVLRDNNIKKIQPASFFLNMRRFHVLDLTFNKVKSICEEDLLNFQGKHFTLL 185
Query 203 ELSS---NQIKEFSPGCFHAIGRLFG------LFLNNVQLGPSLTEKLCLELANTSIRNL 253
LSS + E+ G + G F L L+ S+ ++ +A T I++L
Sbjct 186 RLSSITLQDMNEYWLG-WEKCGNPFKNTSITTLDLSGNGFKESMAKRFFDAIAGTKIQSL 244
Query 254 SLSNS----------QLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYF 303
LSNS N TF GL+ + + DLS + + + F+ LE
Sbjct 245 ILSNSYNMGSSFGHTNFKDPDNFTFKGLEASGVKTCDLSKSKIFALLKSVFSHFTDLEQL 304
Query 304 FLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNME 363
L N I + ++ GL ++ LNL ++F L ID F+ L LE L++
Sbjct 305 TLAQNEINKIDDNAFWGLTHLLKLNLSQNF---------LGSIDSRMFENLDKLEVLDLS 355
Query 364 DNDIPGIKSNMFTGLINLKYLSL 386
N I + F GL NLK L+L
Sbjct 356 YNHIRALGDQSFLGLPNLKELAL 378
Score = 55.5 bits (132), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 40/141 (28%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
Query 408 PLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSY 465
P H+ ++L+ N I+++ +FS L L+ L + G + +RGL ++ + L Y
Sbjct 29 PAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQTPGLVIRNNTFRGLSSLIILKLDY 88
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN-DD 524
N++LQL +F + +L+ L L + L S + F+PL +L +L L +NNI I
Sbjct 89 NQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFFKPLTSLEMLVLRDNNIKKIQPAS 148
Query 525 MLEGLEKLEILDLQHNNLARL 545
+ + +LDL N + +
Sbjct 149 FFLNMRRFHVLDLTFNKVKSI 169
Score = 50.4 bits (119), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 42/128 (33%), Positives = 64/128 (50%), Gaps = 2/128 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K +L +++ L F+ T+L +L L N I KI +N F +L+ L+LS N L
Sbjct 277 VKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLG 336
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAI 220
S L+ L+ L LS N I+AL + N LK+L L +NQ+K G F +
Sbjct 337 SIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPN--LKELALDTNQLKSVPDGIFDRL 394
Query 221 GRLFGLFL 228
L ++L
Sbjct 395 TSLQKIWL 402
Score = 42.0 bits (97), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 33/107 (31%), Positives = 58/107 (54%), Gaps = 2/107 (2%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
L+ L L NE++++ D F T+L +L+L N + I + F L LDLS+N +
Sbjct 301 LEQLTLAQNEINKIDDNAFWGLTHLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIR 360
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+ + + L NL+EL L N+++++ D +SL+K+ L +N
Sbjct 361 ALGDQSFLGLPNLKELALDTNQLKSVPDGIFDRL--TSLQKIWLHTN 405
Score = 37.7 bits (86), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 27/83 (33%), Positives = 42/83 (51%), Gaps = 0/83 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T++ LNL+ N L + + F +L LD+ +N I L + LP LK L L N+
Sbjct 323 THLLKLNLSQNFLGSIDSRMFENLDKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQ 382
Query 111 LSQLSDKTFAFCTNLTELHLMSN 133
L + D F T+L ++ L +N
Sbjct 383 LKSVPDGIFDRLTSLQKIWLHTN 405
>7r52_B B Toll-like receptor 8
Length=807
Score = 72.8 bits (177), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 194/802 (24%), Positives = 300/802 (37%), Gaps = 186/802 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 79
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 80 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 136
Query 140 NNPFVKQKNLITLDLSHNGL-------SSTKLGTQVQLEN-------------------- 172
+ NL L L+ N ++ + G L N
Sbjct 137 KEGISRLINLKNLYLAWNCYXXXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS 196
Query 173 -LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 197 SLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----C 244
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV 289
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 245 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA 302
Query 290 GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 303 SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL----- 356
Query 344 PKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETF 401
+ DDF L L +N+ N I I +F NL+ + LS N + L
Sbjct 357 -REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXXX 415
Query 402 VSL------------------AHS-------PL---------HILNLTKNKISKIESDAF 427
HS PL L+L+ N I I + F
Sbjct 416 XXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQF 475
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQRL 485
L + L+L N Q L+G E+ + ++ KYL LT N F +L L
Sbjct 476 ENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTEL 527
Query 486 MLRRVALKNVDSSPSP----------FQPLRNLTILDLSNNNIANINDDM-LEGLEKLEI 534
V + +S Q NL +L+LS+NNI + D LE +E+
Sbjct 528 SDLEVLDLSYNSXXXXXXXXXHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVEL 587
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELKI 590
+ N L LW + + I KGL +L L+L N IP E F L EL I
Sbjct 588 V-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHI 645
Query 591 ID---------------------------------------------LGLNNLNTLPASV 605
D L N ++ LP+
Sbjct 646 NDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGF 705
Query 606 FNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE- 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 706 LSEVSSLKHLDLSSNLLKTINKSALETKXXTKLSMLELHGNPFECTCD-IGDFRRWMDEH 764
Query 664 THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 765 LNVKIPRLVD-VICASPGDQRG 785
>6v9u_A A Toll-like receptor 8
Length=811
Score = 72.8 bits (177), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 191/806 (24%), Positives = 298/806 (37%), Gaps = 194/806 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGL-------SSTKLGTQVQLEN-------------------- 172
+ NL L L+ N ++ + G L N
Sbjct 141 KEGISRLINLKNLYLAWNCYFNXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS 200
Query 173 -LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 201 SLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----C 248
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV 289
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 249 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA 306
Query 290 GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 307 SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL----- 360
Query 344 PKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL---------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 -REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKXXXXXX 419
Query 387 -----------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
SN + R L + + L+L+ N I I
Sbjct 420 XXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFIG 475
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPS 481
+ F L + L+L N Q L+G E+ + ++ KYL LT N F +
Sbjct 476 PNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASA 527
Query 482 LQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLE 530
L L V + V Q NL +L+LS+NNI + D LE
Sbjct 528 LTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKS 587
Query 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLF 586
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 588 LVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLT 645
Query 587 ELKIID---------------------------------------------LGLNNLNTL 601
EL I D L N ++ L
Sbjct 646 ELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHL 705
Query 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNW 660
P+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W
Sbjct 706 PSGFLSEVSSLKHLDLSSNLLKTINKSALXXXXXTKLSMLELHGNPFECTCD-IGDFRRW 764
Query 661 INE-THTNIPELSSHYLCNTPPHYHG 685
++E + IP L +C +P G
Sbjct 765 MDEHLNVKIPRLVD-VICASPGDQRG 789
>5z14_A A Toll-like receptor 8
Length=811
Score = 72.8 bits (177), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 190/807 (24%), Positives = 299/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINKSAXXXXXXTKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>8pfi_B B Toll-like receptor 8
Length=807
Score = 72.8 bits (177), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 194/802 (24%), Positives = 300/802 (37%), Gaps = 186/802 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 79
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 80 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 136
Query 140 NNPFVKQKNLITLDLSHNGL-------SSTKLGTQVQLEN-------------------- 172
+ NL L L+ N ++ + G L N
Sbjct 137 KEGISRLINLKNLYLAWNCYFXXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS 196
Query 173 -LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 197 SLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----C 244
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV 289
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 245 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA 302
Query 290 GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 303 SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL----- 356
Query 344 PKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETF 401
+ DDF L L +N+ N I I +F NL+ + LS N + L
Sbjct 357 -REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXXX 415
Query 402 VSL------------------AHS-------PL---------HILNLTKNKISKIESDAF 427
HS PL L+L+ N I I + F
Sbjct 416 XXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQF 475
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQRL 485
L + L+L N Q L+G E+ + ++ KYL LT N F +L L
Sbjct 476 ENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTEL 527
Query 486 MLRRVALKNVDSSPSP----------FQPLRNLTILDLSNNNIANINDDM-LEGLEKLEI 534
V + +S Q NL +L+LS+NNI + D LE +E+
Sbjct 528 SDLEVLDLSYNSXXXXXXXXXXXLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVEL 587
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELKI 590
+ N L LW + + I KGL +L L+L N IP E F L EL I
Sbjct 588 V-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHI 645
Query 591 ID---------------------------------------------LGLNNLNTLPASV 605
D L N ++ LP+
Sbjct 646 NDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGF 705
Query 606 FNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE- 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 706 LSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDEH 764
Query 664 THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 765 LNVKIPRLVD-VICASPGDQRG 785
>3zyj_C C LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C
Length=440
Score = 71.6 bits (174), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 84/287 (29%), Positives = 125/287 (44%), Gaps = 44/287 (15%)
Query 400 TFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIF 459
+F L H L IL L++N I IE AF+ L +L L+L N + G + L +
Sbjct 83 SFKHLRH--LEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNG-AFVYLSKLK 139
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS-SPSPFQPLRNLTILDLSNNNI 518
E++L N + +F +PSL+RL L LK + S F+ L NL L+L+ N+
Sbjct 140 ELWLRNNPIESIPSYAFNRIPSLRRLDLGE--LKRLSYISEGAFEGLSNLRYLNLAMCNL 197
Query 519 ANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIP 578
I + L L KL+ LDL N+L+ + PG +GL HL L + + I
Sbjct 198 REIPN--LTPLIKLDELDLSGNHLSAI----RPGS----FQGLMHLQKLWMIQSQIQVIE 247
Query 579 VEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLT 638
F +L L I+L NNL LP +F +L
Sbjct 248 RNAFDNLQSLVEINLAHNNLTLLPHDLFT-------------------------PLHHLE 282
Query 639 ELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
+ + NP++C C+ I W WI + + + CNTPP+ G
Sbjct 283 RIHLHHNPWNCNCD-ILWLSWWIKDMAPSNTACCAR--CNTPPNLKG 326
Score = 66.6 bits (161), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 75/286 (26%), Positives = 119/286 (42%), Gaps = 34/286 (12%)
Query 24 STTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVG 83
S C+ C L +VPD + TN +LNL NQ++ + +F L L +
Sbjct 37 SVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLS 96
Query 84 FNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
N I +E L L L L N L+ + + F + + L EL L +N I+ I + F
Sbjct 97 RNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAF 156
Query 144 VKQKNLITLDLSH-NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKL 202
+ +L LDL LS G L NL+ L L+ ++ + + I L +L
Sbjct 157 NRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLI----KLDEL 212
Query 203 ELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLST 262
+LS N + PG F + L L++ +Q SQ+
Sbjct 213 DLSGNHLSAIRPGSFQGLMHLQKLWM--IQ-------------------------SQIQV 245
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
F L+ +L ++L++NNL ++ +D F L LE L +N
Sbjct 246 IERNAFDNLQ--SLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 289
Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 63/230 (27%), Positives = 108/230 (47%), Gaps = 23/230 (10%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL--KR 331
TN +L+L N + ++ +SF L LE L N+I+ + + +GL N+ L L R
Sbjct 64 TNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNR 123
Query 332 SFTKQSISLASLPK-------------IDDFSFQWLKCLEHLNM-EDNDIPGIKSNMFTG 377
T + + L K I ++F + L L++ E + I F G
Sbjct 124 LTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEG 183
Query 378 LINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
L NL+YL+L + +LR + N T + L L+L+ N +S I +F L HL+ L
Sbjct 184 LSNLRYLNL--AMCNLREIPNLTPL----IKLDELDLSGNHLSAIRPGSFQGLMHLQKLW 237
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+ ++I Q + + L+++ EI L++N L + F + L+R+ L
Sbjct 238 MIQSQI-QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHL 286
Score = 40.8 bits (94), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 28/83 (34%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
+LNL N I V FK L L+I+ L N++ T+ FN +L +L L N +T++
Sbjct 68 LLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTI 127
Query 626 EKKVFGPAFRNLTELDMRFNPFD 648
F L EL +R NP +
Sbjct 128 PNGAF-VYLSKLKELWLRNNPIE 149
Score = 38.9 bits (89), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 53/111 (48%), Gaps = 8/111 (7%)
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
N +L+L N I I + + L LEIL L N++ + I GL++L+
Sbjct 65 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTI--------EIGAFNGLANLNT 116
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
L L N IP F L +LK + L N + ++P+ FN SL+ L+L
Sbjct 117 LELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDL 167
>3zyj_A A LEUCINE-RICH REPEAT-CONTAINING PROTEIN 4C
Length=440
Score = 71.6 bits (174), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 84/287 (29%), Positives = 125/287 (44%), Gaps = 44/287 (15%)
Query 400 TFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIF 459
+F L H L IL L++N I IE AF+ L +L L+L N + G + L +
Sbjct 83 SFKHLRH--LEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNG-AFVYLSKLK 139
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS-SPSPFQPLRNLTILDLSNNNI 518
E++L N + +F +PSL+RL L LK + S F+ L NL L+L+ N+
Sbjct 140 ELWLRNNPIESIPSYAFNRIPSLRRLDLGE--LKRLSYISEGAFEGLSNLRYLNLAMCNL 197
Query 519 ANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIP 578
I + L L KL+ LDL N+L+ + PG +GL HL L + + I
Sbjct 198 REIPN--LTPLIKLDELDLSGNHLSAI----RPGS----FQGLMHLQKLWMIQSQIQVIE 247
Query 579 VEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLT 638
F +L L I+L NNL LP +F +L
Sbjct 248 RNAFDNLQSLVEINLAHNNLTLLPHDLFT-------------------------PLHHLE 282
Query 639 ELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
+ + NP++C C+ I W WI + + + CNTPP+ G
Sbjct 283 RIHLHHNPWNCNCD-ILWLSWWIKDMAPSNTACCAR--CNTPPNLKG 326
Score = 66.6 bits (161), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 75/286 (26%), Positives = 119/286 (42%), Gaps = 34/286 (12%)
Query 24 STTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVG 83
S C+ C L +VPD + TN +LNL NQ++ + +F L L +
Sbjct 37 SVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLS 96
Query 84 FNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
N I +E L L L L N L+ + + F + + L EL L +N I+ I + F
Sbjct 97 RNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAF 156
Query 144 VKQKNLITLDLSH-NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKL 202
+ +L LDL LS G L NL+ L L+ ++ + + I L +L
Sbjct 157 NRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLI----KLDEL 212
Query 203 ELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLST 262
+LS N + PG F + L L++ +Q SQ+
Sbjct 213 DLSGNHLSAIRPGSFQGLMHLQKLWM--IQ-------------------------SQIQV 245
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
F L+ +L ++L++NNL ++ +D F L LE L +N
Sbjct 246 IERNAFDNLQ--SLVEINLAHNNLTLLPHDLFTPLHHLERIHLHHN 289
Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 63/230 (27%), Positives = 108/230 (47%), Gaps = 23/230 (10%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL--KR 331
TN +L+L N + ++ +SF L LE L N+I+ + + +GL N+ L L R
Sbjct 64 TNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNR 123
Query 332 SFTKQSISLASLPK-------------IDDFSFQWLKCLEHLNM-EDNDIPGIKSNMFTG 377
T + + L K I ++F + L L++ E + I F G
Sbjct 124 LTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEG 183
Query 378 LINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
L NL+YL+L + +LR + N T + L L+L+ N +S I +F L HL+ L
Sbjct 184 LSNLRYLNL--AMCNLREIPNLTPL----IKLDELDLSGNHLSAIRPGSFQGLMHLQKLW 237
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+ ++I Q + + L+++ EI L++N L + F + L+R+ L
Sbjct 238 MIQSQI-QVIERNAFDNLQSLVEINLAHNNLTLLPHDLFTPLHHLERIHL 286
Score = 40.8 bits (94), Expect = 0.060, Method: Compositional matrix adjust.
Identities = 28/83 (34%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
+LNL N I V FK L L+I+ L N++ T+ FN +L +L L N +T++
Sbjct 68 LLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTI 127
Query 626 EKKVFGPAFRNLTELDMRFNPFD 648
F L EL +R NP +
Sbjct 128 PNGAF-VYLSKLKELWLRNNPIE 149
Score = 38.9 bits (89), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 53/111 (48%), Gaps = 8/111 (7%)
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
N +L+L N I I + + L LEIL L N++ + I GL++L+
Sbjct 65 NTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTI--------EIGAFNGLANLNT 116
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
L L N IP F L +LK + L N + ++P+ FN SL+ L+L
Sbjct 117 LELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESIPSYAFNRIPSLRRLDL 167
>3ul9_A A Toll-like receptor 4, Variable lymphocyte receptor B
Length=278
Score = 70.1 bits (170), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 61/218 (28%), Positives = 100/218 (46%), Gaps = 26/218 (12%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 15 CEELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 74
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 75 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 134
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDI---------------------- 193
N + S KL L NL+ L LS+NKIQ++ +L +
Sbjct 135 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 194
Query 194 ---FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
F LK+L L +NQ+K G F + L ++L
Sbjct 195 PGAFKEIRLKELALDTNQLKSVPDGIFDRLTSLQKIWL 232
Score = 55.8 bits (133), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 59/228 (26%), Positives = 96/228 (42%), Gaps = 37/228 (16%)
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
LS+N L SF P LQ L L R ++ ++ +Q L +L+ L L+ N I ++
Sbjct 36 LSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--YQSLSHLSTLILTGNPIQSLA 93
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF 582
GL L+ L NLA L PI LK L L++ + F ++P E F
Sbjct 94 LGAFSGLSSLQKLVAVETNLASLENF-----PIGHLKTLKELNVAHNLIQSF-KLP-EYF 146
Query 583 KDLFELKIIDLGLNNLNTLPASVFN---------------------------NQVSLKSL 615
+L L+ +DL N + ++ + ++ LK L
Sbjct 147 SNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLKEL 206
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
L N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 207 ALDTNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 253
Score = 35.0 bits (79), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 36/135 (27%), Positives = 56/135 (41%), Gaps = 8/135 (6%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
LDLS N + ++ +L++LDL + + A + LSHL L L
Sbjct 34 LDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--------YQSLSHLSTLILT 85
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N + + F L L+ + NL +L + +LK LN+ NLI S + +
Sbjct 86 GNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEY 145
Query 631 GPAFRNLTELDMRFN 645
NL LD+ N
Sbjct 146 FSNLTNLEHLDLSSN 160
Score = 35.0 bits (79), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 18/127 (14%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDLS+N L +G+ SF P+L+ L IQ + + L ++ L L + QS+
Sbjct 34 LDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGN-PIQSL 92
Query 339 SLAS----------------LPKIDDFSFQWLKCLEHLNMEDNDIPGIK-SNMFTGLINL 381
+L + L +++F LK L+ LN+ N I K F+ L NL
Sbjct 93 ALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNL 152
Query 382 KYLSLSN 388
++L LS+
Sbjct 153 EHLDLSS 159
>3ul8_A A Toll-like receptor 4, Variable lymphocyte receptor B
Length=279
Score = 69.7 bits (169), Expect = 1e-11, Method: Compositional matrix adjust.
Identities = 61/218 (28%), Positives = 100/218 (46%), Gaps = 26/218 (12%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 16 CMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 75
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 76 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVALETNLASLENFPIGHLKTLKELNVAH 135
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDI---------------------- 193
N + S KL L NL+ L LS+NKIQ++ +L +
Sbjct 136 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 195
Query 194 ---FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
F LK+L L +NQ+K G F + L ++L
Sbjct 196 PGAFKEIRLKELALDTNQLKSVPDGIFDRLTSLQKIWL 233
Score = 55.5 bits (132), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 59/228 (26%), Positives = 96/228 (42%), Gaps = 37/228 (16%)
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
LS+N L SF P LQ L L R ++ ++ +Q L +L+ L L+ N I ++
Sbjct 37 LSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--YQSLSHLSTLILTGNPIQSLA 94
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF 582
GL L+ L NLA L PI LK L L++ + F ++P E F
Sbjct 95 LGAFSGLSSLQKLVALETNLASLENF-----PIGHLKTLKELNVAHNLIQSF-KLP-EYF 147
Query 583 KDLFELKIIDLGLNNLNTLPASVFN---------------------------NQVSLKSL 615
+L L+ +DL N + ++ + ++ LK L
Sbjct 148 SNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLKEL 207
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
L N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 208 ALDTNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 254
Score = 35.0 bits (79), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 18/127 (14%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDLS+N L +G+ SF P+L+ L IQ + + L ++ L L + QS+
Sbjct 35 LDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGN-PIQSL 93
Query 339 SLAS----------------LPKIDDFSFQWLKCLEHLNMEDNDIPGIK-SNMFTGLINL 381
+L + L +++F LK L+ LN+ N I K F+ L NL
Sbjct 94 ALGAFSGLSSLQKLVALETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNL 153
Query 382 KYLSLSN 388
++L LS+
Sbjct 154 EHLDLSS 160
Score = 34.7 bits (78), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 36/135 (27%), Positives = 56/135 (41%), Gaps = 8/135 (6%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
LDLS N + ++ +L++LDL + + A + LSHL L L
Sbjct 35 LDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--------YQSLSHLSTLILT 86
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N + + F L L+ + NL +L + +LK LN+ NLI S + +
Sbjct 87 GNPIQSLALGAFSGLSSLQKLVALETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEY 146
Query 631 GPAFRNLTELDMRFN 645
NL LD+ N
Sbjct 147 FSNLTNLEHLDLSSN 161
>7r53_B B Toll-like receptor 8
Length=807
Score = 72.4 bits (176), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 194/802 (24%), Positives = 297/802 (37%), Gaps = 186/802 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 79
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 80 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 136
Query 140 NNPFVKQKNLITLDLSHNGL-------SSTKLGTQVQLEN-------------------- 172
+ NL L L+ N ++ + G L N
Sbjct 137 KEGISRLINLKNLYLAWNXXXXXXXXKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS 196
Query 173 -LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 197 SLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----C 244
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV 289
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 245 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA 302
Query 290 GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 303 SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL----- 356
Query 344 PKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETF 401
+ DDF L L +N+ N I I +F NL+ + LS N + L
Sbjct 357 -REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXXX 415
Query 402 VSL------------------AHS-------PL---------HILNLTKNKISKIESDAF 427
HS PL L+L+ N I I + F
Sbjct 416 XXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQF 475
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQRL 485
L + L+L N Q L+G E+ + ++ KYL LT N F +L L
Sbjct 476 ENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTEL 527
Query 486 MLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLEI 534
V + V Q NL +L+LS+NNI + D LE +E+
Sbjct 528 SDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVEL 587
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELKI 590
+ N L LW I KGL +L L+L N IP E F L EL I
Sbjct 588 V-FSGNRLDILWNXXXXRY-ISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHI 645
Query 591 ID---------------------------------------------LGLNNLNTLPASV 605
D L N ++ LP+
Sbjct 646 NDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGF 705
Query 606 FNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE- 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 706 LSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDEH 764
Query 664 THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 765 LNVKIPRLVD-VICASPGDQRG 785
>6kya_A A Toll-like receptor 8
Length=811
Score = 72.4 bits (176), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 190/807 (24%), Positives = 299/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINKSXXXXXXXTKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>8pfi_A A Toll-like receptor 8
Length=807
Score = 72.4 bits (176), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 188/806 (23%), Positives = 297/806 (37%), Gaps = 194/806 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 79
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 80 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 136
Query 140 NNPFVKQKNLITLDLSHNGL-------SSTKLGTQVQLEN-------------------- 172
+ NL L L+ N ++ + G L N
Sbjct 137 KEGISRLINLKNLYLAWNCYFXXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS 196
Query 173 -LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 197 SLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----C 244
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV 289
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 245 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA 302
Query 290 GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 303 SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL----- 356
Query 344 PKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS--------------- 387
+ DDF L L +N+ N I I +F NL+ + LS
Sbjct 357 -REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXXX 415
Query 388 ------------------------NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
N + R L + + L+L+ N I I
Sbjct 416 XXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFIG 471
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQ 483
+ F L + L+L N Q L+G E+ + ++ KYL LT N +
Sbjct 472 PNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASA 523
Query 484 RLMLRRVALKNVDSSPSPF------------QPLRNLTILDLSNNNIANINDDM-LEGLE 530
L + + ++ + F Q NL +L+LS+NNI + D LE
Sbjct 524 LTELSDLEVLDLSYNSHYFXXXXXTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKS 583
Query 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLF 586
+E++ N L LW I KGL +L L+L N IP E F L
Sbjct 584 LVELV-FSGNRLDILWXXXXXRY-ISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLT 641
Query 587 ELKIID---------------------------------------------LGLNNLNTL 601
EL I D L N ++ L
Sbjct 642 ELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHL 701
Query 602 PASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNW 660
P+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W
Sbjct 702 PSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRW 760
Query 661 INE-THTNIPELSSHYLCNTPPHYHG 685
++E + IP L +C +P G
Sbjct 761 MDEHLNVKIPRLVD-VICASPGDQRG 785
>7r52_A A Toll-like receptor 8
Length=807
Score = 72.4 bits (176), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 194/802 (24%), Positives = 299/802 (37%), Gaps = 186/802 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 79
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 80 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 136
Query 140 NNPFVKQKNLITLDLSHNGL-------SSTKLGTQVQLEN-------------------- 172
+ NL L L+ N ++ + G L N
Sbjct 137 KEGISRLINLKNLYLAWNCYXXXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS 196
Query 173 -LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 197 SLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----C 244
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV 289
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 245 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA 302
Query 290 GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 303 SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL----- 356
Query 344 PKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETF 401
+ DDF L L +N+ N I I +F NL+ + LS N + L
Sbjct 357 -REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXXX 415
Query 402 VSL------------------AHS-------PL---------HILNLTKNKISKIESDAF 427
HS PL L+L+ N I I + F
Sbjct 416 XXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQF 475
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQRL 485
L + L+L N Q L+G E+ + ++ KYL LT N F +L L
Sbjct 476 ENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTEL 527
Query 486 MLRRVALKNVDSSPSP----------FQPLRNLTILDLSNNNIANINDDM-LEGLEKLEI 534
V + +S Q NL +L+LS+NNI + D LE +E+
Sbjct 528 SDLEVLDLSYNSHXXXXXXXXHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVEL 587
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELKI 590
+ N L LW + + I KGL +L L+L N IP E F L EL I
Sbjct 588 V-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHI 645
Query 591 ID---------------------------------------------LGLNNLNTLPASV 605
D L N ++ LP+
Sbjct 646 NDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGF 705
Query 606 FNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE- 663
SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 706 LXXVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDEH 764
Query 664 THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 765 LNVKIPRLVD-VICASPGDQRG 785
>7crf_B B Toll-like receptor 8
Length=811
Score = 72.4 bits (176), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 190/818 (23%), Positives = 303/818 (37%), Gaps = 196/818 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXEFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVE-KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINXXXXXXXXXXKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHGFPVRLFDTSSC 696
W++E + IP L +C +P G + + ++C
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRGKSIVSLELTTC 800
>5awa_A A Toll-like receptor 8
Length=811
Score = 72.0 bits (175), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 190/789 (24%), Positives = 295/789 (37%), Gaps = 187/789 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINKSALXXXXXTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPEL 671
+ IP L
Sbjct 768 HLNVKIPRL 776
>2z65_B B Toll-like receptor 4, Variable lymphocyte receptor B
Length=276
Score = 69.7 bits (169), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 61/218 (28%), Positives = 100/218 (46%), Gaps = 26/218 (12%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 14 CMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 73
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 74 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 133
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDI---------------------- 193
N + S KL L NL+ L LS+NKIQ++ +L +
Sbjct 134 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 193
Query 194 ---FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
F LK+L L +NQ+K G F + L ++L
Sbjct 194 PGAFKEIRLKELALDTNQLKSVPDGIFDRLTSLQKIWL 231
Score = 55.8 bits (133), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 59/228 (26%), Positives = 96/228 (42%), Gaps = 37/228 (16%)
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
LS+N L SF P LQ L L R ++ ++ +Q L +L+ L L+ N I ++
Sbjct 35 LSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--YQSLSHLSTLILTGNPIQSLA 92
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF 582
GL L+ L NLA L PI LK L L++ + F ++P E F
Sbjct 93 LGAFSGLSSLQKLVAVETNLASLENF-----PIGHLKTLKELNVAHNLIQSF-KLP-EYF 145
Query 583 KDLFELKIIDLGLNNLNTLPASVFN---------------------------NQVSLKSL 615
+L L+ +DL N + ++ + ++ LK L
Sbjct 146 SNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLKEL 205
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
L N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 206 ALDTNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 252
Score = 35.0 bits (79), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 36/135 (27%), Positives = 56/135 (41%), Gaps = 8/135 (6%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
LDLS N + ++ +L++LDL + + A + LSHL L L
Sbjct 33 LDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--------YQSLSHLSTLILT 84
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N + + F L L+ + NL +L + +LK LN+ NLI S + +
Sbjct 85 GNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEY 144
Query 631 GPAFRNLTELDMRFN 645
NL LD+ N
Sbjct 145 FSNLTNLEHLDLSSN 159
Score = 35.0 bits (79), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 18/127 (14%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDLS+N L +G+ SF P+L+ L IQ + + L ++ L L + QS+
Sbjct 33 LDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGN-PIQSL 91
Query 339 SLAS----------------LPKIDDFSFQWLKCLEHLNMEDNDIPGIK-SNMFTGLINL 381
+L + L +++F LK L+ LN+ N I K F+ L NL
Sbjct 92 ALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNL 151
Query 382 KYLSLSN 388
++L LS+
Sbjct 152 EHLDLSS 158
>2z62_A A Toll-like receptor 4, Variable lymphocyte receptor B
Length=276
Score = 69.7 bits (169), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 61/218 (28%), Positives = 100/218 (46%), Gaps = 26/218 (12%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 14 CMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 73
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 74 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 133
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDI---------------------- 193
N + S KL L NL+ L LS+NKIQ++ +L +
Sbjct 134 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 193
Query 194 ---FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
F LK+L L +NQ+K G F + L ++L
Sbjct 194 PGAFKEIRLKELALDTNQLKSVPDGIFDRLTSLQKIWL 231
Score = 55.8 bits (133), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 59/228 (26%), Positives = 96/228 (42%), Gaps = 37/228 (16%)
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
LS+N L SF P LQ L L R ++ ++ +Q L +L+ L L+ N I ++
Sbjct 35 LSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--YQSLSHLSTLILTGNPIQSLA 92
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF 582
GL L+ L NLA L PI LK L L++ + F ++P E F
Sbjct 93 LGAFSGLSSLQKLVAVETNLASLENF-----PIGHLKTLKELNVAHNLIQSF-KLP-EYF 145
Query 583 KDLFELKIIDLGLNNLNTLPASVFN---------------------------NQVSLKSL 615
+L L+ +DL N + ++ + ++ LK L
Sbjct 146 SNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLKEL 205
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
L N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 206 ALDTNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 252
Score = 35.0 bits (79), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 36/135 (27%), Positives = 56/135 (41%), Gaps = 8/135 (6%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
LDLS N + ++ +L++LDL + + A + LSHL L L
Sbjct 33 LDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--------YQSLSHLSTLILT 84
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N + + F L L+ + NL +L + +LK LN+ NLI S + +
Sbjct 85 GNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEY 144
Query 631 GPAFRNLTELDMRFN 645
NL LD+ N
Sbjct 145 FSNLTNLEHLDLSSN 159
Score = 35.0 bits (79), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 18/127 (14%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDLS+N L +G+ SF P+L+ L IQ + + L ++ L L + QS+
Sbjct 33 LDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGN-PIQSL 91
Query 339 SLAS----------------LPKIDDFSFQWLKCLEHLNMEDNDIPGIK-SNMFTGLINL 381
+L + L +++F LK L+ LN+ N I K F+ L NL
Sbjct 92 ALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNL 151
Query 382 KYLSLSN 388
++L LS+
Sbjct 152 EHLDLSS 158
>2z65_A A Toll-like receptor 4, Variable lymphocyte receptor B
Length=276
Score = 69.7 bits (169), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 61/218 (28%), Positives = 100/218 (46%), Gaps = 26/218 (12%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 14 CMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 73
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 74 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 133
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDI---------------------- 193
N + S KL L NL+ L LS+NKIQ++ +L +
Sbjct 134 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 193
Query 194 ---FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
F LK+L L +NQ+K G F + L ++L
Sbjct 194 PGAFKEIRLKELALDTNQLKSVPDGIFDRLTSLQKIWL 231
Score = 55.8 bits (133), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 59/228 (26%), Positives = 96/228 (42%), Gaps = 37/228 (16%)
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
LS+N L SF P LQ L L R ++ ++ +Q L +L+ L L+ N I ++
Sbjct 35 LSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--YQSLSHLSTLILTGNPIQSLA 92
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF 582
GL L+ L NLA L PI LK L L++ + F ++P E F
Sbjct 93 LGAFSGLSSLQKLVAVETNLASLENF-----PIGHLKTLKELNVAHNLIQSF-KLP-EYF 145
Query 583 KDLFELKIIDLGLNNLNTLPASVFN---------------------------NQVSLKSL 615
+L L+ +DL N + ++ + ++ LK L
Sbjct 146 SNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLKEL 205
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
L N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 206 ALDTNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 252
Score = 35.0 bits (79), Expect = 2.7, Method: Compositional matrix adjust.
Identities = 36/135 (27%), Positives = 56/135 (41%), Gaps = 8/135 (6%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
LDLS N + ++ +L++LDL + + A + LSHL L L
Sbjct 33 LDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--------YQSLSHLSTLILT 84
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N + + F L L+ + NL +L + +LK LN+ NLI S + +
Sbjct 85 GNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEY 144
Query 631 GPAFRNLTELDMRFN 645
NL LD+ N
Sbjct 145 FSNLTNLEHLDLSSN 159
Score = 35.0 bits (79), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 18/127 (14%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDLS+N L +G+ SF P+L+ L IQ + + L ++ L L + QS+
Sbjct 33 LDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGN-PIQSL 91
Query 339 SLAS----------------LPKIDDFSFQWLKCLEHLNMEDNDIPGIK-SNMFTGLINL 381
+L + L +++F LK L+ LN+ N I K F+ L NL
Sbjct 92 ALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNL 151
Query 382 KYLSLSN 388
++L LS+
Sbjct 152 EHLDLSS 158
>7nuw_A A Toll-like receptor 1
Length=162
Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 42/147 (29%), Positives = 77/147 (52%), Gaps = 4/147 (3%)
Query 755 EYAAYIIHAYKDKDWVW-EHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
++ A+I ++ D WV E ++EKE ++ CL ER+F G +E I+ I++S K
Sbjct 13 QFHAFISYSGHDSFWVKNELLPNLEKE--GMQICLHERNFVPGKSIVENIITCIEKSYKS 70
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
IFV++ + ++ C ++++ A + +S+IL+ LE IP Y + + + +
Sbjct 71 IFVLSPNFVQSEWC-HYELYFAHHNLFHEGSNSLILILLEPIPQYSIPSSYHKLKSLMAR 129
Query 874 HCILNWPVQKERIGAFRHKLQVALGSK 900
L WP +K + G F L+ A+ K
Sbjct 130 RTYLEWPKEKSKRGLFWANLRAAINIK 156
>3ula_C C Toll-like receptor 4, Variable lymphocyte receptor B
Length=279
Score = 69.3 bits (168), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 61/218 (28%), Positives = 100/218 (46%), Gaps = 26/218 (12%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 16 CMELNFYKIPDNLPFSTKNLDLSWNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 75
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 76 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 135
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDI---------------------- 193
N + S KL L NL+ L LS+NKIQ++ +L +
Sbjct 136 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 195
Query 194 ---FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
F LK+L L +NQ+K G F + L ++L
Sbjct 196 PGAFKEIRLKELALDTNQLKSVPDGIFDRLTSLQKIWL 233
Score = 55.5 bits (132), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 59/228 (26%), Positives = 96/228 (42%), Gaps = 37/228 (16%)
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
LS+N L SF P LQ L L R ++ ++ +Q L +L+ L L+ N I ++
Sbjct 37 LSWNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--YQSLSHLSTLILTGNPIQSLA 94
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF 582
GL L+ L NLA L PI LK L L++ + F ++P E F
Sbjct 95 LGAFSGLSSLQKLVAVETNLASLENF-----PIGHLKTLKELNVAHNLIQSF-KLP-EYF 147
Query 583 KDLFELKIIDLGLNNLNTLPASVFN---------------------------NQVSLKSL 615
+L L+ +DL N + ++ + ++ LK L
Sbjct 148 SNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLKEL 207
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
L N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 208 ALDTNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 254
Score = 35.0 bits (79), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 36/135 (27%), Positives = 56/135 (41%), Gaps = 8/135 (6%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
LDLS N + ++ +L++LDL + + A + LSHL L L
Sbjct 35 LDLSWNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--------YQSLSHLSTLILT 86
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N + + F L L+ + NL +L + +LK LN+ NLI S + +
Sbjct 87 GNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEY 146
Query 631 GPAFRNLTELDMRFN 645
NL LD+ N
Sbjct 147 FSNLTNLEHLDLSSN 161
Score = 34.7 bits (78), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 18/127 (14%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDLS+N L +G+ SF P+L+ L IQ + + L ++ L L + QS+
Sbjct 35 LDLSWNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGN-PIQSL 93
Query 339 SLAS----------------LPKIDDFSFQWLKCLEHLNMEDNDIPGIK-SNMFTGLINL 381
+L + L +++F LK L+ LN+ N I K F+ L NL
Sbjct 94 ALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNL 153
Query 382 KYLSLSN 388
++L LS+
Sbjct 154 EHLDLSS 160
>3ula_A A Toll-like receptor 4, Variable lymphocyte receptor B
Length=279
Score = 69.3 bits (168), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 61/218 (28%), Positives = 100/218 (46%), Gaps = 26/218 (12%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 16 CMELNFYKIPDNLPFSTKNLDLSWNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 75
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 76 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 135
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDI---------------------- 193
N + S KL L NL+ L LS+NKIQ++ +L +
Sbjct 136 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 195
Query 194 ---FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
F LK+L L +NQ+K G F + L ++L
Sbjct 196 PGAFKEIRLKELALDTNQLKSVPDGIFDRLTSLQKIWL 233
Score = 55.5 bits (132), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 59/228 (26%), Positives = 96/228 (42%), Gaps = 37/228 (16%)
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
LS+N L SF P LQ L L R ++ ++ +Q L +L+ L L+ N I ++
Sbjct 37 LSWNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--YQSLSHLSTLILTGNPIQSLA 94
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF 582
GL L+ L NLA L PI LK L L++ + F ++P E F
Sbjct 95 LGAFSGLSSLQKLVAVETNLASLENF-----PIGHLKTLKELNVAHNLIQSF-KLP-EYF 147
Query 583 KDLFELKIIDLGLNNLNTLPASVFN---------------------------NQVSLKSL 615
+L L+ +DL N + ++ + ++ LK L
Sbjct 148 SNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLKEL 207
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
L N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 208 ALDTNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 254
Score = 35.0 bits (79), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 36/135 (27%), Positives = 56/135 (41%), Gaps = 8/135 (6%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
LDLS N + ++ +L++LDL + + A + LSHL L L
Sbjct 35 LDLSWNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--------YQSLSHLSTLILT 86
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N + + F L L+ + NL +L + +LK LN+ NLI S + +
Sbjct 87 GNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEY 146
Query 631 GPAFRNLTELDMRFN 645
NL LD+ N
Sbjct 147 FSNLTNLEHLDLSSN 161
Score = 34.7 bits (78), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 18/127 (14%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDLS+N L +G+ SF P+L+ L IQ + + L ++ L L + QS+
Sbjct 35 LDLSWNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGN-PIQSL 93
Query 339 SLAS----------------LPKIDDFSFQWLKCLEHLNMEDNDIPGIK-SNMFTGLINL 381
+L + L +++F LK L+ LN+ N I K F+ L NL
Sbjct 94 ALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNL 153
Query 382 KYLSLSN 388
++L LS+
Sbjct 154 EHLDLSS 160
>5o0o_H H Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 47.8 bits (112), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.6 bits (109), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>7nux_A A Toll-like receptor 1
Length=162
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 42/147 (29%), Positives = 77/147 (52%), Gaps = 4/147 (3%)
Query 755 EYAAYIIHAYKDKDWVW-EHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
++ A+I ++ D WV E ++EKE ++ CL ER+F G +E I+ I++S K
Sbjct 13 QFHAFISYSGHDSFWVKNELLPNLEKE--GMQICLHERNFVPGKSIVENIITCIEKSYKS 70
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
IFV++ + ++ C ++++ A + +S+IL+ LE IP Y + + + +
Sbjct 71 IFVLSPNFVQSEWC-HYELYFAHHNLFHEGSNSLILILLEPIPQYSIPSSYHKLKSLMAR 129
Query 874 HCILNWPVQKERIGAFRHKLQVALGSK 900
L WP +K + G F L+ A+ K
Sbjct 130 RTYLEWPKEKSKRGLFWANLRAAINIK 156
>5o0o_G G Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 47.8 bits (112), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.6 bits (109), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0o_B B Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 47.8 bits (112), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.6 bits (109), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0m_A A Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.2 bits (147), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 48.1 bits (113), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 47.0 bits (110), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0o_D D Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 47.4 bits (111), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.2 bits (108), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0k_B B Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.6 bits (148), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 48.5 bits (114), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5gs2_D B repebody
Length=273
Score = 69.3 bits (168), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 58/185 (31%), Positives = 89/185 (48%), Gaps = 13/185 (7%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L L L ++ S + L NLT L L+ N + ++ + + + L L+ L L
Sbjct 62 LPNVRYLALGGNKLHDI----SALKELTNLTYLILTGNQLQSLPNGVFDKLTNLKELVLV 117
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P G L L++L+ L N +P VF L L +DL N L
Sbjct 118 ENQLQSL-----PDGVFDKLTNLTYLY---LYHNQLQSLPKGVFDKLTNLTRLDLDNNQL 169
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L+L N + SV VF +LT + + NP+DC C I +
Sbjct 170 QSLPEGVFDKLTQLKQLSLNDNQLKSVPDGVFD-RLTSLTHIWLLNNPWDCACSDILYLS 228
Query 659 NWINE 663
WI++
Sbjct 229 RWISQ 233
Score = 61.6 bits (148), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 49/135 (36%), Positives = 68/135 (50%), Gaps = 2/135 (1%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
++L L L L N+L L + F TNL EL L+ N +Q + + F K NL L L
Sbjct 82 KELTNLTYLILTGNQLQSLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTYLYLY 141
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
HN L S G +L NL L L NN++Q+L D + LK+L L+ NQ+K G
Sbjct 142 HNQLQSLPKGVFDKLTNLTRLDLDNNQLQSLPEGVFDKL--TQLKQLSLNDNQLKSVPDG 199
Query 216 CFHAIGRLFGLFLNN 230
F + L ++L N
Sbjct 200 VFDRLTSLTHIWLLN 214
Score = 58.2 bits (139), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 53/164 (32%), Positives = 80/164 (49%), Gaps = 3/164 (2%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L + N +
Sbjct 42 SIDQIIANNSDIKSVQGIQYLP-NVRYLALGGNKLHDISA--LKELTNLTYLILTGNQLQ 98
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLT L+L N +Q + F K N
Sbjct 99 SLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTYLYLYHNQLQSLPKGVFDKLTN 158
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
L LDL +N L S G +L L++L L++N+++++ D
Sbjct 159 LTRLDLDNNQLQSLPEGVFDKLTQLKQLSLNDNQLKSVPDGVFD 202
Score = 58.2 bits (139), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 48/131 (37%), Positives = 63/131 (48%), Gaps = 0/131 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T L LT NQL+ LP F + + L L + N + L + KL L L L HN+
Sbjct 85 TNLTYLILTGNQLQSLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTYLYLYHNQ 144
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L F TNLT L L +N +Q + F K L L L+ N L S G +L
Sbjct 145 LQSLPKGVFDKLTNLTRLDLDNNQLQSLPEGVFDKLTQLKQLSLNDNQLKSVPDGVFDRL 204
Query 171 ENLQELLLSNN 181
+L + L NN
Sbjct 205 TSLTHIWLLNN 215
Score = 55.5 bits (132), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 37/96 (39%), Positives = 53/96 (55%), Gaps = 3/96 (3%)
Query 41 KLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
+L +PD D TN+T L L HNQL+ LP F + + LT LD+ N + L + K
Sbjct 120 QLQSLPDGVFDKLTNLTYLYLYHNQLQSLPKGVFDKLTNLTRLDLDNNQLQSLPEGVFDK 179
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
L LK L+L N+L + D F T+LT + L++N
Sbjct 180 LTQLKQLSLNDNQLKSVPDGVFDRLTSLTHIWLLNN 215
Score = 35.4 bits (80), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 40/145 (28%), Positives = 60/145 (41%), Gaps = 31/145 (21%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L+L+ N++Q+L + D N LK+L L NQ++ G F + L L+L
Sbjct 83 ELTNLTYLILTGNQLQSLPNGVFDKLTN--LKELVLVENQLQSLPDGVFDKLTNLTYLYL 140
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
++QL + F K TNLT LDL N L
Sbjct 141 ---------------------------YHNQLQSLPKGVFD--KLTNLTRLDLDNNQLQS 171
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHL 313
+ F L QL+ L N ++ +
Sbjct 172 LPEGVFDKLTQLKQLSLNDNQLKSV 196
>5o0o_C C Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 47.4 bits (111), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.6 bits (109), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0o_A A Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 60.5 bits (145), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.1 bits (144), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/195 (30%), Positives = 93/195 (48%), Gaps = 6/195 (3%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLA 405
+ SFQ + L L + N + I + FTGL L+ L LS++ L + TF L
Sbjct 49 VPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLG 107
Query 406 HSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSY 465
H LH L+L + + ++ F L L+ L L N + Q L +R L N+ ++L
Sbjct 108 H--LHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHG 164
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N+ + ++F + SL RL+L + + V P F+ L L L L NN++ + ++
Sbjct 165 NRIPSVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEV 222
Query 526 LEGLEKLEILDLQHN 540
L L L+ L L N
Sbjct 223 LMPLRSLQYLRLNDN 237
Score = 60.1 bits (144), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 47.4 bits (111), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.2 bits (108), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0n_A A Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 47.8 bits (112), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.6 bits (109), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0m_B B Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.2 bits (147), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 48.1 bits (113), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0q_C C Reticulon-4 receptor
Length=334
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.6 bits (148), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 48.5 bits (114), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.6 bits (109), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>3ul7_A A Toll-like receptor 4, Variable lymphocyte receptor B
Length=278
Score = 69.3 bits (168), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 61/218 (28%), Positives = 100/218 (46%), Gaps = 26/218 (12%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L ++PD+LP + L+L+ N LR L + +F + +L LD+ I +E Q
Sbjct 15 CMELNFYKIPDNLPFSTKNLDLSWNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQ 74
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L L L N + L+ F+ ++L +L + ++ ++N P K L L+++H
Sbjct 75 SLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAH 134
Query 157 NGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDI---------------------- 193
N + S KL L NL+ L LS+NKIQ++ +L +
Sbjct 135 NLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQ 194
Query 194 ---FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
F LK+L L +NQ+K G F + L ++L
Sbjct 195 PGAFKEIRLKELALDTNQLKSVPDGIFDRLTSLQKIWL 232
Score = 55.5 bits (132), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 59/228 (26%), Positives = 96/228 (42%), Gaps = 37/228 (16%)
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
LS+N L SF P LQ L L R ++ ++ +Q L +L+ L L+ N I ++
Sbjct 36 LSWNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--YQSLSHLSTLILTGNPIQSLA 93
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF 582
GL L+ L NLA L PI LK L L++ + F ++P E F
Sbjct 94 LGAFSGLSSLQKLVAVETNLASLENF-----PIGHLKTLKELNVAHNLIQSF-KLP-EYF 146
Query 583 KDLFELKIIDLGLNNLNTLPASVFN---------------------------NQVSLKSL 615
+L L+ +DL N + ++ + ++ LK L
Sbjct 147 SNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLKEL 206
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
L N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 207 ALDTNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 253
Score = 35.0 bits (79), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 36/135 (27%), Positives = 56/135 (41%), Gaps = 8/135 (6%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
LDLS N + ++ +L++LDL + + A + LSHL L L
Sbjct 34 LDLSWNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGA--------YQSLSHLSTLILT 85
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N + + F L L+ + NL +L + +LK LN+ NLI S + +
Sbjct 86 GNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEY 145
Query 631 GPAFRNLTELDMRFN 645
NL LD+ N
Sbjct 146 FSNLTNLEHLDLSSN 160
Score = 34.7 bits (78), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 18/127 (14%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDLS+N L +G+ SF P+L+ L IQ + + L ++ L L + QS+
Sbjct 34 LDLSWNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGN-PIQSL 92
Query 339 SLAS----------------LPKIDDFSFQWLKCLEHLNMEDNDIPGIK-SNMFTGLINL 381
+L + L +++F LK L+ LN+ N I K F+ L NL
Sbjct 93 ALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNL 152
Query 382 KYLSLSN 388
++L LS+
Sbjct 153 EHLDLSS 159
>5o0q_A A Reticulon-4 receptor
Length=334
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.6 bits (148), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 48.1 bits (113), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 47.0 bits (110), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>3rfj_A A Internalin B, repeat modules, Variable lymphocyte receptor
Length=279
Score = 69.3 bits (168), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 58/185 (31%), Positives = 89/185 (48%), Gaps = 13/185 (7%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L L L ++ S + L NLT L L+ N + ++ + + + L L+ L L
Sbjct 62 LPNVRYLALGGNKLHDI----SALKELTNLTYLILTGNQLQSLPNGVFDKLTNLKELVLV 117
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P G L L++L+ L N +P VF L L +DL N L
Sbjct 118 ENQLQSL-----PDGVFDKLTNLTYLY---LYHNQLQSLPKGVFDKLTNLTRLDLDNNQL 169
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L+L N + SV VF +LT + + NP+DC C I +
Sbjct 170 QSLPEGVFDKLTQLKQLSLNDNQLKSVPDGVFD-RLTSLTHIWLLNNPWDCACSDILYLS 228
Query 659 NWINE 663
WI++
Sbjct 229 RWISQ 233
Score = 61.6 bits (148), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 49/135 (36%), Positives = 68/135 (50%), Gaps = 2/135 (1%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
++L L L L N+L L + F TNL EL L+ N +Q + + F K NL L L
Sbjct 82 KELTNLTYLILTGNQLQSLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTYLYLY 141
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
HN L S G +L NL L L NN++Q+L D + LK+L L+ NQ+K G
Sbjct 142 HNQLQSLPKGVFDKLTNLTRLDLDNNQLQSLPEGVFDKL--TQLKQLSLNDNQLKSVPDG 199
Query 216 CFHAIGRLFGLFLNN 230
F + L ++L N
Sbjct 200 VFDRLTSLTHIWLLN 214
Score = 58.2 bits (139), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 53/164 (32%), Positives = 80/164 (49%), Gaps = 3/164 (2%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L + N +
Sbjct 42 SIDQIIANNSDIKSVQGIQYLP-NVRYLALGGNKLHDISA--LKELTNLTYLILTGNQLQ 98
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLT L+L N +Q + F K N
Sbjct 99 SLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTYLYLYHNQLQSLPKGVFDKLTN 158
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
L LDL +N L S G +L L++L L++N+++++ D
Sbjct 159 LTRLDLDNNQLQSLPEGVFDKLTQLKQLSLNDNQLKSVPDGVFD 202
Score = 58.2 bits (139), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 48/131 (37%), Positives = 63/131 (48%), Gaps = 0/131 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T L LT NQL+ LP F + + L L + N + L + KL L L L HN+
Sbjct 85 TNLTYLILTGNQLQSLPNGVFDKLTNLKELVLVENQLQSLPDGVFDKLTNLTYLYLYHNQ 144
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L F TNLT L L +N +Q + F K L L L+ N L S G +L
Sbjct 145 LQSLPKGVFDKLTNLTRLDLDNNQLQSLPEGVFDKLTQLKQLSLNDNQLKSVPDGVFDRL 204
Query 171 ENLQELLLSNN 181
+L + L NN
Sbjct 205 TSLTHIWLLNN 215
Score = 55.5 bits (132), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 37/96 (39%), Positives = 53/96 (55%), Gaps = 3/96 (3%)
Query 41 KLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
+L +PD D TN+T L L HNQL+ LP F + + LT LD+ N + L + K
Sbjct 120 QLQSLPDGVFDKLTNLTYLYLYHNQLQSLPKGVFDKLTNLTRLDLDNNQLQSLPEGVFDK 179
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
L LK L+L N+L + D F T+LT + L++N
Sbjct 180 LTQLKQLSLNDNQLKSVPDGVFDRLTSLTHIWLLNN 215
Score = 35.4 bits (80), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 40/145 (28%), Positives = 60/145 (41%), Gaps = 31/145 (21%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L+L+ N++Q+L + D N LK+L L NQ++ G F + L L+L
Sbjct 83 ELTNLTYLILTGNQLQSLPNGVFDKLTN--LKELVLVENQLQSLPDGVFDKLTNLTYLYL 140
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
++QL + F K TNLT LDL N L
Sbjct 141 ---------------------------YHNQLQSLPKGVFD--KLTNLTRLDLDNNQLQS 171
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHL 313
+ F L QL+ L N ++ +
Sbjct 172 LPEGVFDKLTQLKQLSLNDNQLKSV 196
>5o0o_F F Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 47.8 bits (112), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.6 bits (109), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0k_A A Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.2 bits (147), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 48.1 bits (113), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.6 bits (109), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0l_A A Reticulon-4 receptor
Length=323
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.2 bits (147), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 48.1 bits (113), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.6 bits (109), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0p_B B Reticulon-4 receptor
Length=334
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.2 bits (147), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 48.1 bits (113), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0r_A A Reticulon-4 receptor
Length=334
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.6 bits (148), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 48.5 bits (114), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0o_E E Reticulon-4 receptor
Length=323
Score = 69.7 bits (169), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/222 (26%), Positives = 93/222 (42%), Gaps = 5/222 (2%)
Query 18 GMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQL 77
G C + C L VP +P + + L N++ +PAA+F L
Sbjct 1 GSPCPGACVCYNEPKVTTSCPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNL 60
Query 78 TSLDVGFNTISKLEPELCQKLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQ 136
T L + N +++++ L +L+ L+L N +L + TF +L LHL ++
Sbjct 61 TILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLR 120
Query 137 KIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN 196
++ F L L L N L + T L NL L L N+I ++
Sbjct 121 ELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL-- 178
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL--NNVQLGPS 236
SL +L L N + P F +GRL L+L NN+ + P+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.1 bits (144), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.1 bits (144), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 47.4 bits (111), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.2 bits (108), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0l_B B Reticulon-4 receptor
Length=323
Score = 69.7 bits (169), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.2 bits (147), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.6 bits (109), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0q_D D Reticulon-4 receptor
Length=334
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.2 bits (147), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 48.1 bits (113), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.6 bits (109), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0q_B B Reticulon-4 receptor
Length=334
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.2 bits (147), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 46.6 bits (109), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>5o0p_A A Reticulon-4 receptor
Length=334
Score = 70.1 bits (170), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 61.2 bits (147), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 48.1 bits (113), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 47.0 bits (110), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>7nt7_A A Toll-like receptor 1
Length=163
Score = 66.6 bits (161), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 42/147 (29%), Positives = 77/147 (52%), Gaps = 4/147 (3%)
Query 755 EYAAYIIHAYKDKDWVW-EHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
++ A+I ++ D WV E ++EKE ++ CL ER+F G +E I+ I++S K
Sbjct 13 QFHAFISYSGHDSFWVKNELLPNLEKE--GMQICLHERNFVPGKSIVENIITCIEKSYKS 70
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
IFV++ + ++ C ++++ A + +S+IL+ LE IP Y + + + +
Sbjct 71 IFVLSPNFVQSEWC-HYELYFAHHNLFHEGSNSLILILLEPIPQYSIPSSYHKLKSLMAR 129
Query 874 HCILNWPVQKERIGAFRHKLQVALGSK 900
L WP +K + G F L+ A+ K
Sbjct 130 RTYLEWPKEKSKRGLFWANLRAAINIK 156
>7r86_B B Reticulon-4 receptor
Length=285
Score = 68.9 bits (167), Expect = 3e-11, Method: Composition-based stats.
Identities = 61/161 (38%), Positives = 82/161 (51%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 34 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 91
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
A+L + P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 92 --AQL----HVVDPTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 144
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 145 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 181
Score = 63.5 bits (153), Expect = 2e-09, Method: Composition-based stats.
Identities = 60/221 (27%), Positives = 95/221 (43%), Gaps = 8/221 (4%)
Query 22 ASSTTKCTVSHE---VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLT 78
AS C +E C L VP +P + + L N++ +PAA+F LT
Sbjct 1 ASCPGACVCYNEPKVTTSCPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLT 60
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQK 137
L + N +++++ L +L+ L+L N +L + TF +L LHL +++
Sbjct 61 ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRE 120
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANS 197
+ F L L L N L + T L NL L L N+I ++
Sbjct 121 LGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFR--GLH 178
Query 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFL--NNVQLGPS 236
SL +L L N + P F +GRL L+L NN+ + P+
Sbjct 179 SLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPA 219
Score = 61.6 bits (148), Expect = 8e-09, Method: Composition-based stats.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 52 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 108
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 109 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 167
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 168 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 225
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 226 RSLQYLRLNDN 236
Score = 60.8 bits (146), Expect = 2e-08, Method: Composition-based stats.
Identities = 62/209 (30%), Positives = 94/209 (45%), Gaps = 25/209 (12%)
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SF S R LT IL L N +++I++ AF+ L LE LDL N +
Sbjct 52 SFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVD 98
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPLRN 507
+ GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L N
Sbjct 99 PTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDLGN 155
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
LT L L N I ++ + GL L+ L L N++AR+ HA + L L L
Sbjct 156 LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLMTL 207
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L +N +P EV L L+ + L N
Sbjct 208 YLFANNLSMLPAEVLMPLRSLQYLRLNDN 236
Score = 51.6 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 58 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 117
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 118 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 177
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 178 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 235
Query 207 N 207
N
Sbjct 236 N 236
Score = 47.8 bits (112), Expect = 3e-04, Method: Composition-based stats.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 40 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 89
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 90 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 134
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 135 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 187
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 188 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 233
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 43/148 (29%), Positives = 69/148 (47%), Gaps = 13/148 (9%)
Query 248 TSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
T + L LS N+QL TTF GL +L L L L +G F L L+Y +L+
Sbjct 81 TLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 138
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L + N
Sbjct 139 DNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLLHQNH 189
Query 367 IPGIKSNMFTGLINLKYLSL-SNSFTSL 393
+ + + F L L L L +N+ + L
Sbjct 190 VARVHPHAFRDLGRLMTLYLFANNLSML 217
Score = 42.0 bits (97), Expect = 0.017, Method: Composition-based stats.
Identities = 53/204 (26%), Positives = 88/204 (43%), Gaps = 13/204 (6%)
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
N ++ V SF L +L N + + + + GL + L+L + A L
Sbjct 43 NRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN--------AQL 94
Query 344 PKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS 403
+D +F L L L+++ + + +F GL L+YL L ++ +L+ L + TF
Sbjct 95 HVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNTFRD 152
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYL 463
L + L L L N+I + AF L L+ L L N + + + +R L + +YL
Sbjct 153 LGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMTLYL 209
Query 464 SYNKYLQLTRNSFALVPSLQRLML 487
N L + SLQ L L
Sbjct 210 FANNLSMLPAEVLMPLRSLQYLRL 233
>5wyx_B B Toll-like receptor 8
Length=811
Score = 71.6 bits (174), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 190/807 (24%), Positives = 300/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRVALKNVDSSPSP----------FQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + +S Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYXXXXXVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINKSXXXXXXXTKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>5o0r_B B Reticulon-4 receptor
Length=334
Score = 69.7 bits (169), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 59/161 (37%), Positives = 79/161 (49%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 92
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
+ P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 93 AQLHVVD------PTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 145
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 146 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 182
Score = 62.0 bits (149), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 20 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 79
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 80 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 140 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL--HSLDRLLLHQNHVARVHPH 197
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 198 AFRDLGRLMTLYLFANNLSMLPA 220
Score = 60.5 bits (145), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 53 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 109
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 110 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 168
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 169 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 226
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 227 RSLQYLRLNDN 237
Score = 60.1 bits (144), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 62/211 (29%), Positives = 95/211 (45%), Gaps = 25/211 (12%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
+ SF S R LT IL L N +++I++ AF+ L LE LDL N
Sbjct 51 AASFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHV 97
Query 447 LTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPL 505
+ + GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L
Sbjct 98 VDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDL 154
Query 506 RNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
NLT L L N I ++ + GL L+ L L N++AR+ HA + L L
Sbjct 155 GNLTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLM 206
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L L +N +P EV L L+ + L N
Sbjct 207 TLYLFANNLSMLPAEVLMPLRSLQYLRLNDN 237
Score = 48.5 bits (114), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 59 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 118
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 119 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 178
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 179 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 236
Query 207 N 207
N
Sbjct 237 N 237
Score = 47.0 bits (110), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 91 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 136 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 188
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 189 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 234
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
Q L++ I A+S +++ L N+I F + L L+L++ L
Sbjct 23 QGLQAVPTGIPASS--QRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAF-- 78
Query 244 ELANTSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
T + L LS N+QL TTF GL +L L L L +G F L L+Y
Sbjct 79 -TGLTLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQY 135
Query 303 FFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNM 362
+L+ NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L +
Sbjct 136 LYLQDNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLL 186
Query 363 EDNDIPGIKSNMFTGLINLKYLSL 386
N + + + F L L L L
Sbjct 187 HQNHVARVHPHAFRDLGRLMTLYL 210
Score = 42.4 bits (98), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 54/207 (26%), Positives = 89/207 (43%), Gaps = 13/207 (6%)
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L N ++ V SF L +L N + + + + GL + L+L +
Sbjct 41 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-------- 92
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
A L +D +F L L L+++ + + +F GL L+YL L ++ +L+ L + T
Sbjct 93 AQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNT 150
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
F L + L L L N+I + AF L L+ L L N + + + +R L +
Sbjct 151 FRDLGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMT 207
Query 461 IYLSYNKYLQLTRNSFALVPSLQRLML 487
+YL N L + SLQ L L
Sbjct 208 LYLFANNLSMLPAEVLMPLRSLQYLRL 234
>1fyv_A A TOLL-LIKE RECEPTOR 1
Length=169
Score = 66.6 bits (161), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 42/147 (29%), Positives = 77/147 (52%), Gaps = 4/147 (3%)
Query 755 EYAAYIIHAYKDKDWVW-EHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
++ A+I ++ D WV E ++EKE ++ CL ER+F G +E I+ I++S K
Sbjct 12 QFHAFISYSGHDSFWVKNELLPNLEKE--GMQICLHERNFVPGKSIVENIITCIEKSYKS 69
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
IFV++ + ++ C ++++ A + +S+IL+ LE IP Y + + + +
Sbjct 70 IFVLSPNFVQSEWC-HYELYFAHHNLFHEGSNSLILILLEPIPQYSIPSSYHKLKSLMAR 128
Query 874 HCILNWPVQKERIGAFRHKLQVALGSK 900
L WP +K + G F L+ A+ K
Sbjct 129 RTYLEWPKEKSKRGLFWANLRAAINIK 155
>4r07_C C Toll-like receptor 8
Length=811
Score = 71.2 bits (173), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 192/803 (24%), Positives = 299/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSVE-KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTINXXXXXXXTTTKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>7r86_A A Reticulon-4 receptor
Length=285
Score = 68.9 bits (167), Expect = 3e-11, Method: Composition-based stats.
Identities = 61/161 (38%), Positives = 82/161 (51%), Gaps = 13/161 (8%)
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
S QR+ L + +V ++ FQ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 34 SSQRIFLHGNRISHVPAAS--FQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN 91
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
A+L + P F GL HLH L+L+ G E+ +F+ L L+ + L NNL
Sbjct 92 --AQL----HVVDPTTF-HGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNLQA 144
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
LP + F + +L L L N I SV + AFR L LD
Sbjct 145 LPDNTFRDLGNLTHLFLHGNRIPSVPEH----AFRGLHSLD 181
Score = 63.2 bits (152), Expect = 3e-09, Method: Composition-based stats.
Identities = 56/203 (28%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + + L N++ +PAA+F LT L + N +++++
Sbjct 19 CPQQGLQAVPTGIPASSQRIFLHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFT 78
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF +L LHL ++++ F L L L
Sbjct 79 GLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 138
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ SL +L L N + P
Sbjct 139 DNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFR--GLHSLDRLLLHQNHVARVHPH 196
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ + P+
Sbjct 197 AFRDLGRLMTLYLFANNLSMLPA 219
Score = 61.6 bits (148), Expect = 9e-09, Method: Composition-based stats.
Identities = 58/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
SFQ + L L + N + I + FTGL L+ L LS++ L + TF L H L
Sbjct 52 SFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN-AQLHVVDPTTFHGLGH--L 108
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
H L+L + + ++ F L L+ L L N + Q L +R L N+ ++L N+
Sbjct 109 HTLHLDRCGLRELGPGLFRGLAALQYLYLQDNNL-QALPDNTFRDLGNLTHLFLHGNRIP 167
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
+ ++F + SL RL+L + + V P F+ L L L L NN++ + ++L L
Sbjct 168 SVPEHAFRGLHSLDRLLLHQNHVARV--HPHAFRDLGRLMTLYLFANNLSMLPAEVLMPL 225
Query 530 EKLEILDLQHN 540
L+ L L N
Sbjct 226 RSLQYLRLNDN 236
Score = 60.8 bits (146), Expect = 2e-08, Method: Composition-based stats.
Identities = 62/209 (30%), Positives = 94/209 (45%), Gaps = 25/209 (12%)
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
SF S R LT IL L N +++I++ AF+ L LE LDL N +
Sbjct 52 SFQSCRNLT-------------ILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVD 98
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP-SPFQPLRN 507
+ GL ++ ++L +L F + +LQ L L+ N+ + P + F+ L N
Sbjct 99 PTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQD---NNLQALPDNTFRDLGN 155
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
LT L L N I ++ + GL L+ L L N++AR+ HA + L L L
Sbjct 156 LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVARVHPHA--------FRDLGRLMTL 207
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L +N +P EV L L+ + L N
Sbjct 208 YLFANNLSMLPAEVLMPLRSLQYLRLNDN 236
Score = 51.6 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 54/181 (30%), Positives = 72/181 (40%), Gaps = 27/181 (15%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT------------------------- 86
N+T+L L N L R+ AA FT + L LD+ N
Sbjct 58 NLTILWLHSNALARIDAAAFTGLTLLEQLDLSDNAQLHVVDPTTFHGLGHLHTLHLDRCG 117
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ +L P L + L L+ L LQ N L L D TF NLT L L N I + + F
Sbjct 118 LRELGPGLFRGLAALQYLYLQDNNLQALPDNTFRDLGNLTHLFLHGNRIPSVPEHAFRGL 177
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+L L L N ++ L L L L N + L +E L SL+ L L+
Sbjct 178 HSLDRLLLHQNHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVL--MPLRSLQYLRLND 235
Query 207 N 207
N
Sbjct 236 N 236
Score = 47.4 bits (111), Expect = 3e-04, Method: Composition-based stats.
Identities = 61/226 (27%), Positives = 94/226 (42%), Gaps = 34/226 (15%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN++ +I F L LDLS
Sbjct 40 LHGNRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLS---------- 89
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFG 225
+N Q ++ L L L L ++E PG F + L
Sbjct 90 -----DNAQLHVVDPTTFHGL----------GHLHTLHLDRCGLRELGPGLFRGLAALQY 134
Query 226 LFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
L+L NN+Q P T + +L N + +L L +++ + F GL +L L L
Sbjct 135 LYLQDNNLQALPDNTFR---DLGN--LTHLFLHGNRIPSVPEHAFRGLH--SLDRLLLHQ 187
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
N++ V +F L +L +L NN+ L + L L +++YL L
Sbjct 188 NHVARVHPHAFRDLGRLMTLYLFANNLSMLPAEVLMPLRSLQYLRL 233
Score = 44.7 bits (104), Expect = 0.003, Method: Composition-based stats.
Identities = 43/148 (29%), Positives = 69/148 (47%), Gaps = 13/148 (9%)
Query 248 TSIRNLSLS-NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLE 306
T + L LS N+QL TTF GL +L L L L +G F L L+Y +L+
Sbjct 81 TLLEQLDLSDNAQLHVVDPTTFHGLG--HLHTLHLDRCGLRELGPGLFRGLAALQYLYLQ 138
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND 366
NN+Q L ++ L N+ +L L + +P + + +F+ L L+ L + N
Sbjct 139 DNNLQALPDNTFRDLGNLTHLFLHGN---------RIPSVPEHAFRGLHSLDRLLLHQNH 189
Query 367 IPGIKSNMFTGLINLKYLSL-SNSFTSL 393
+ + + F L L L L +N+ + L
Sbjct 190 VARVHPHAFRDLGRLMTLYLFANNLSML 217
Score = 42.0 bits (97), Expect = 0.017, Method: Composition-based stats.
Identities = 53/204 (26%), Positives = 88/204 (43%), Gaps = 13/204 (6%)
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
N ++ V SF L +L N + + + + GL + L+L + A L
Sbjct 43 NRISHVPAASFQSCRNLTILWLHSNALARIDAAAFTGLTLLEQLDLSDN--------AQL 94
Query 344 PKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS 403
+D +F L L L+++ + + +F GL L+YL L ++ +L+ L + TF
Sbjct 95 HVVDPTTFHGLGHLHTLHLDRCGLRELGPGLFRGLAALQYLYLQDN--NLQALPDNTFRD 152
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYL 463
L + L L L N+I + AF L L+ L L N + + + +R L + +YL
Sbjct 153 LGN--LTHLFLHGNRIPSVPEHAFRGLHSLDRLLLHQNHVAR-VHPHAFRDLGRLMTLYL 209
Query 464 SYNKYLQLTRNSFALVPSLQRLML 487
N L + SLQ L L
Sbjct 210 FANNLSMLPAEVLMPLRSLQYLRL 233
>5awc_C C Toll-like receptor 8
Length=811
Score = 71.2 bits (173), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 192/803 (24%), Positives = 297/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPXX 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKK-VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
LK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W++E
Sbjct 709 XXXXXXXLKHLDLSSNLLKTINKSXXXXXXXXKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>4qdh_A A Variable lymphocyte receptor B, Toll-like receptor 9
chimera
Length=438
Score = 70.1 bits (170), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 82/292 (28%), Positives = 132/292 (45%), Gaps = 40/292 (14%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S C+ LT VP +P++ T L L N+L+ LP F + +QLT L + N
Sbjct 10 SRCSCSGTEIRCNSKGLTSVPTGIPSSATRLELESNKLQSLPHGVFDKLTQLTKLSLSRN 69
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
+ ++PE+ L L+ L+L HN ++Q ++ F TNL L L N + F
Sbjct 70 NLVTIKPEMFVNLSRLQCLSLSHNSIAQAVNGSQFLPLTNLQVLDLSHNKLDLYHWKSFS 129
Query 145 KQKNLITLDLSHNG--LSSTKLGTQ----VQLENLQELLLSNNKIQALKSEELDIFANSS 198
+ L LDLS+N +G L LQ L L++N I S L+ ++S
Sbjct 130 ELPQLQALDLSYNSQPFXXXXIGHNFSFVTHLSMLQSLSLAHNDIHTRVSSHLN---SNS 186
Query 199 LKKLELSSNQIKEFSPGCFHAIGRLF---GLFLNNVQLGPSLTEKLCLELANTSIRNLSL 255
++ L+ S N +GR++ GL+L+ Q L+ L L+L+ ++ L
Sbjct 187 VRFLDFSGN-----------GMGRMWDEGGLYLHFFQ---GLSGLLKLDLSQNNLHILRP 232
Query 256 SN------SQLSTTSNTTFLG-LKWT------NLTMLDLSYNNLNVVGNDSF 294
N S + +L WT NL +LDL+ N L + N +
Sbjct 233 QNLDNLPKSLKLLSLRDNYLSFFNWTSLSFLPNLEVLDLAGNQLKALTNGTL 284
Score = 66.6 bits (161), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 85/348 (24%), Positives = 135/348 (39%), Gaps = 82/348 (24%)
Query 393 LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
L++L + F L L L+L++N + I+ + F L L+ L L N I Q + G ++
Sbjct 47 LQSLPHGVFDKLTQ--LTKLSLSRNNLVTIKPEMFVNLSRLQCLSLSHNSIAQAVNGSQF 104
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML----RRVALKNVDSSPSPFQPLRNL 508
L N+ + LS+NK SF+ +P LQ L L + + + S L L
Sbjct 105 LPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSQPFXXXXIGHNFSFVTHLSML 164
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
L L++N+I L + LD N + R+W G ++F +GLS L L+
Sbjct 165 QSLSLAHNDIHTRVSSHLNS-NSVRFLDFSGNGMGRMWDEG--GLYLHFFQGLSGLLKLD 221
Query 569 LESNGFDEIPVEVFKD-------------------------LFELKIIDLGLNNL----- 598
L N + + + L L+++DL N L
Sbjct 222 LSQNNLHILRPQNLDNLPKSLKLLSLRDNYLSFFNWTSLSFLPNLEVLDLAGNQLKALTN 281
Query 599 NTLP-------------------ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
TLP + F V LK +NL N++ +V++ FGP NL E
Sbjct 282 GTLPNGTLLQKLDVSSNSIVSVVPAFFALAVELKEVNLSHNILKTVDRSWFGPIVMNLKE 341
Query 640 LD------------------------MRFNPFDCTCESIAWFVNWINE 663
L + NP+DC+C I + W+N+
Sbjct 342 LALDTNQLKSVPDGIFDRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 389
Score = 39.3 bits (90), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 31/85 (36%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
L LESN +P VF L +L + L NNL T+ +F N L+ L+L N S+
Sbjct 40 LELESNKLQSLPHGVFDKLTQLTKLSLSRNNLVTIKPEMFVNLSRLQCLSLSHN---SIA 96
Query 627 KKVFGPAF---RNLTELDMRFNPFD 648
+ V G F NL LD+ N D
Sbjct 97 QAVNGSQFLPLTNLQVLDLSHNKLD 121
>4r08_C C Toll-like receptor 8
Length=811
Score = 70.9 bits (172), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 192/803 (24%), Positives = 299/803 (37%), Gaps = 188/803 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSG 708
Query 605 VFNNQVSLKSLNLQKNLITSV-EKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ SLK L+L NL+ ++ L+ L++ NPF+CTC+ I F W++E
Sbjct 709 FLSEVSSLKHLDLSSNLLKTIXXXXXXXXXXXKLSMLELHGNPFECTCD-IGDFRRWMDE 767
Query 664 -THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 768 HLNVKIPRLVD-VICASPGDQRG 789
>6ty5_A A Toll-like receptor 8
Length=807
Score = 70.9 bits (172), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 192/818 (23%), Positives = 298/818 (36%), Gaps = 218/818 (27%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 79
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 80 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 136
Query 140 NNPFVKQKNLITLDLSHNGL-------SSTKLGTQVQLEN-------------------- 172
+ NL L L+ N ++ + G L N
Sbjct 137 KEGISRLINLKNLYLAWNCYFXXXCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS 196
Query 173 -LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 197 SLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----C 244
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV 289
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 245 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA 302
Query 290 GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 303 SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL----- 356
Query 344 PKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETF 401
+ DDF L L +N+ N I I +F NL+ + LS N + L
Sbjct 357 -REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXXX 415
Query 402 VSL------------------AHS-------PL---------HILNLTKNKISKIESDAF 427
HS PL L+L+ N I I + F
Sbjct 416 XXXXXXXXXXXXXXXXXXXXDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQF 475
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
L + L+L N Q L+G E+ + ++ KYL LT N
Sbjct 476 ENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNN------------- 514
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNN----IANIND--DMLEGLEKLEILDLQHNN 541
R+ N S L +L +LDLS N+ IA + + ++ L++L+L HNN
Sbjct 515 -RLDFDNA----SALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNN 569
Query 542 LARLWKHANPGGP-----------------------IYFLKGLSHLHILNLESNGFDEIP 578
+ L N I KGL +L L+L N IP
Sbjct 570 IYTLTXKYNLESKSLVELVFSGNRLDILWXXXXNRYISIFKGLKNLTRLDLSLNRLKHIP 629
Query 579 VEVF----KDLFELKIID------------------------------------------ 592
E F L EL I D
Sbjct 630 NEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLR 689
Query 593 ---LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNPFD 648
L N ++ LP+ + SLK L+L NL+ ++ K L+ L++ NPF+
Sbjct 690 TLLLSHNRISHLPSGFLSXVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFE 749
Query 649 CTCESIAWFVNWINE-THTNIPELSSHYLCNTPPHYHG 685
CTC+ I F W++E + IP L +C +P G
Sbjct 750 CTCD-IGDFRRWMDEHLNVKIPRLVD-VICASPGDQRG 785
>1xcd_A A Decorin
Length=329
Score = 68.9 bits (167), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 72/284 (25%), Positives = 112/284 (39%), Gaps = 59/284 (21%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C V CS L L +VP DLP + +L+L +N++ + +F L +L + N
Sbjct 28 RCQCHLRVVQCSDLGLEKVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLHTLILINNK 87
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
ISK+ P L L+ L L N+L +L +K L EL + N I K++ + F
Sbjct 88 ISKISPGAFAPLVKLERLYLSKNQLKELPEK---MPKTLQELRVHENEITKVRKSVFNGL 144
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+I ++L N L S+ + N Q +K L + ++
Sbjct 145 NQMIVVELGTNPLKSSG--------------IENGAFQGMK----------KLSYIRIAD 180
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
I G L PSLTE L L ++++
Sbjct 181 TNITTIPQG-----------------LPPSLTE-------------LHLDGNKITKVDAA 210
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNI 310
+ GL NL L LS+N+++ V N S A P L L N +
Sbjct 211 SLKGL--NNLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKL 252
Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 59/220 (27%), Positives = 95/220 (43%), Gaps = 36/220 (16%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG----------QELTGQE------- 451
LH L L NKISKI AF+ L LE L L N++ QEL E
Sbjct 78 LHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHENEITKVR 137
Query 452 ---WRGLENIFEIYLSYN--KYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
+ GL + + L N K + +F +++L R+A N+ + P P
Sbjct 138 KSVFNGLNQMIVVELGTNPLKSSGIENGAFQ---GMKKLSYIRIADTNITTIPQGLPP-- 192
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+LT L L N I ++ L+GL L L L N+++ + + L HL
Sbjct 193 SLTELHLDGNKITKVDAASLKGLNNLAKLGLSFNSISAVDNGS--------LANTPHLRE 244
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVF 606
L+L +N ++P D ++++ L NN++ + ++ F
Sbjct 245 LHLNNNKLVKVP-GGLADHKYIQVVYLHNNNISAIGSNDF 283
Score = 43.1 bits (100), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 56/248 (23%), Positives = 99/248 (40%), Gaps = 21/248 (8%)
Query 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQ 336
+LDL N + + + F L L L N I + + L + L L ++
Sbjct 55 ALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKN---- 110
Query 337 SISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTL 396
L LP+ + K L+ L + +N+I ++ ++F GL + + L + +
Sbjct 111 --QLKELPE------KMPKTLQELRVHENEITKVRKSVFNGLNQMIVVELGTNPLKSSGI 162
Query 397 TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLE 456
N F + L + + I+ I L L L N+I ++ +GL
Sbjct 163 ENGAFQGMKK--LSYIRIADTNITTIPQGLPPSLTELH---LDGNKI-TKVDAASLKGLN 216
Query 457 NIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
N+ ++ LS+N + S A P L+ L L L V P + + ++ L NN
Sbjct 217 NLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKLVKV---PGGLADHKYIQVVYLHNN 273
Query 517 NIANINDD 524
NI+ I +
Sbjct 274 NISAIGSN 281
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 53/212 (25%), Positives = 92/212 (43%), Gaps = 42/212 (20%)
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
+LDL N+I E+ +++ L+N+ + L NK +++ +FA + L+RL L + LK
Sbjct 56 LLDLQNNKI-TEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKE 114
Query 495 V-DSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ + P Q LR + N I + + GL ++ +++L NP
Sbjct 115 LPEKMPKTLQELR------VHENEITKVRKSVFNGLNQMIVVELG----------TNP-- 156
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
L+S+G + + K L ++I D N+ T+P + SL
Sbjct 157 ---------------LKSSGIENGAFQGMKKLSYIRIAD---TNITTIPQGL---PPSLT 195
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L+L N IT V+ NL +L + FN
Sbjct 196 ELHLDGNKITKVDAASLK-GLNNLAKLGLSFN 226
Score = 35.0 bits (79), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
+LDL NN I I D + L+ L L L +N ++++ +PG L L L
Sbjct 55 ALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKI----SPGA----FAPLVKLERLY 106
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
L N E+P ++ K L EL++ + N + + SVFN
Sbjct 107 LSKNQLKELPEKMPKTLQELRVHE---NEITKVRKSVFN 142
>1xec_B B Decorin
Length=329
Score = 68.9 bits (167), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 72/284 (25%), Positives = 112/284 (39%), Gaps = 59/284 (21%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C V CS L L +VP DLP + +L+L +N++ + +F L +L + N
Sbjct 28 RCQCHLRVVQCSDLGLEKVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLHTLILINNK 87
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
ISK+ P L L+ L L N+L +L +K L EL + N I K++ + F
Sbjct 88 ISKISPGAFAPLVKLERLYLSKNQLKELPEK---MPKTLQELRVHENEITKVRKSVFNGL 144
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+I ++L N L S+ + N Q +K L + ++
Sbjct 145 NQMIVVELGTNPLKSSG--------------IENGAFQGMK----------KLSYIRIAD 180
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
I G L PSLTE L L ++++
Sbjct 181 TNITTIPQG-----------------LPPSLTE-------------LHLDGNKITKVDAA 210
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNI 310
+ GL NL L LS+N+++ V N S A P L L N +
Sbjct 211 SLKGL--NNLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKL 252
Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 59/220 (27%), Positives = 95/220 (43%), Gaps = 36/220 (16%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG----------QELTGQE------- 451
LH L L NKISKI AF+ L LE L L N++ QEL E
Sbjct 78 LHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHENEITKVR 137
Query 452 ---WRGLENIFEIYLSYN--KYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
+ GL + + L N K + +F +++L R+A N+ + P P
Sbjct 138 KSVFNGLNQMIVVELGTNPLKSSGIENGAFQ---GMKKLSYIRIADTNITTIPQGLPP-- 192
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+LT L L N I ++ L+GL L L L N+++ + + L HL
Sbjct 193 SLTELHLDGNKITKVDAASLKGLNNLAKLGLSFNSISAVDNGS--------LANTPHLRE 244
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVF 606
L+L +N ++P D ++++ L NN++ + ++ F
Sbjct 245 LHLNNNKLVKVP-GGLADHKYIQVVYLHNNNISAIGSNDF 283
Score = 43.1 bits (100), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 56/248 (23%), Positives = 99/248 (40%), Gaps = 21/248 (8%)
Query 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQ 336
+LDL N + + + F L L L N I + + L + L L ++
Sbjct 55 ALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKN---- 110
Query 337 SISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTL 396
L LP+ + K L+ L + +N+I ++ ++F GL + + L + +
Sbjct 111 --QLKELPE------KMPKTLQELRVHENEITKVRKSVFNGLNQMIVVELGTNPLKSSGI 162
Query 397 TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLE 456
N F + L + + I+ I L L L N+I ++ +GL
Sbjct 163 ENGAFQGMKK--LSYIRIADTNITTIPQGLPPSLTELH---LDGNKI-TKVDAASLKGLN 216
Query 457 NIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
N+ ++ LS+N + S A P L+ L L L V P + + ++ L NN
Sbjct 217 NLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKLVKV---PGGLADHKYIQVVYLHNN 273
Query 517 NIANINDD 524
NI+ I +
Sbjct 274 NISAIGSN 281
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 53/212 (25%), Positives = 92/212 (43%), Gaps = 42/212 (20%)
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
+LDL N+I E+ +++ L+N+ + L NK +++ +FA + L+RL L + LK
Sbjct 56 LLDLQNNKI-TEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKE 114
Query 495 V-DSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ + P Q LR + N I + + GL ++ +++L NP
Sbjct 115 LPEKMPKTLQELR------VHENEITKVRKSVFNGLNQMIVVELG----------TNP-- 156
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
L+S+G + + K L ++I D N+ T+P + SL
Sbjct 157 ---------------LKSSGIENGAFQGMKKLSYIRIAD---TNITTIPQGL---PPSLT 195
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L+L N IT V+ NL +L + FN
Sbjct 196 ELHLDGNKITKVDAASLK-GLNNLAKLGLSFN 226
Score = 35.0 bits (79), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
+LDL NN I I D + L+ L L L +N ++++ +PG L L L
Sbjct 55 ALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKI----SPGA----FAPLVKLERLY 106
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
L N E+P ++ K L EL++ + N + + SVFN
Sbjct 107 LSKNQLKELPEKMPKTLQELRVHE---NEITKVRKSVFN 142
>1xec_A A Decorin
Length=329
Score = 68.9 bits (167), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 72/284 (25%), Positives = 112/284 (39%), Gaps = 59/284 (21%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C V CS L L +VP DLP + +L+L +N++ + +F L +L + N
Sbjct 28 RCQCHLRVVQCSDLGLEKVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLHTLILINNK 87
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
ISK+ P L L+ L L N+L +L +K L EL + N I K++ + F
Sbjct 88 ISKISPGAFAPLVKLERLYLSKNQLKELPEK---MPKTLQELRVHENEITKVRKSVFNGL 144
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+I ++L N L S+ + N Q +K L + ++
Sbjct 145 NQMIVVELGTNPLKSSG--------------IENGAFQGMK----------KLSYIRIAD 180
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
I G L PSLTE L L ++++
Sbjct 181 TNITTIPQG-----------------LPPSLTE-------------LHLDGNKITKVDAA 210
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNI 310
+ GL NL L LS+N+++ V N S A P L L N +
Sbjct 211 SLKGL--NNLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKL 252
Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 59/220 (27%), Positives = 95/220 (43%), Gaps = 36/220 (16%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG----------QELTGQE------- 451
LH L L NKISKI AF+ L LE L L N++ QEL E
Sbjct 78 LHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHENEITKVR 137
Query 452 ---WRGLENIFEIYLSYN--KYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
+ GL + + L N K + +F +++L R+A N+ + P P
Sbjct 138 KSVFNGLNQMIVVELGTNPLKSSGIENGAFQ---GMKKLSYIRIADTNITTIPQGLPP-- 192
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+LT L L N I ++ L+GL L L L N+++ + + L HL
Sbjct 193 SLTELHLDGNKITKVDAASLKGLNNLAKLGLSFNSISAVDNGS--------LANTPHLRE 244
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVF 606
L+L +N ++P D ++++ L NN++ + ++ F
Sbjct 245 LHLNNNKLVKVP-GGLADHKYIQVVYLHNNNISAIGSNDF 283
Score = 43.1 bits (100), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 56/248 (23%), Positives = 99/248 (40%), Gaps = 21/248 (8%)
Query 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQ 336
+LDL N + + + F L L L N I + + L + L L ++
Sbjct 55 ALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKN---- 110
Query 337 SISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTL 396
L LP+ + K L+ L + +N+I ++ ++F GL + + L + +
Sbjct 111 --QLKELPE------KMPKTLQELRVHENEITKVRKSVFNGLNQMIVVELGTNPLKSSGI 162
Query 397 TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLE 456
N F + L + + I+ I L L L N+I ++ +GL
Sbjct 163 ENGAFQGMKK--LSYIRIADTNITTIPQGLPPSLTELH---LDGNKI-TKVDAASLKGLN 216
Query 457 NIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
N+ ++ LS+N + S A P L+ L L L V P + + ++ L NN
Sbjct 217 NLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKLVKV---PGGLADHKYIQVVYLHNN 273
Query 517 NIANINDD 524
NI+ I +
Sbjct 274 NISAIGSN 281
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 53/212 (25%), Positives = 92/212 (43%), Gaps = 42/212 (20%)
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
+LDL N+I E+ +++ L+N+ + L NK +++ +FA + L+RL L + LK
Sbjct 56 LLDLQNNKI-TEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKE 114
Query 495 V-DSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ + P Q LR + N I + + GL ++ +++L NP
Sbjct 115 LPEKMPKTLQELR------VHENEITKVRKSVFNGLNQMIVVELG----------TNP-- 156
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
L+S+G + + K L ++I D N+ T+P + SL
Sbjct 157 ---------------LKSSGIENGAFQGMKKLSYIRIAD---TNITTIPQGL---PPSLT 195
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L+L N IT V+ NL +L + FN
Sbjct 196 ELHLDGNKITKVDAASLK-GLNNLAKLGLSFN 226
Score = 35.0 bits (79), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
+LDL NN I I D + L+ L L L +N ++++ +PG L L L
Sbjct 55 ALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKI----SPGA----FAPLVKLERLY 106
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
L N E+P ++ K L EL++ + N + + SVFN
Sbjct 107 LSKNQLKELPEKMPKTLQELRVHE---NEITKVRKSVFN 142
>4qdh_B B Variable lymphocyte receptor B, Toll-like receptor 9
chimera
Length=438
Score = 69.7 bits (169), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 82/292 (28%), Positives = 132/292 (45%), Gaps = 40/292 (14%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S C+ LT VP +P++ T L L N+L+ LP F + +QLT L + N
Sbjct 10 SRCSCSGTEIRCNSKGLTSVPTGIPSSATRLELESNKLQSLPHGVFDKLTQLTKLSLSRN 69
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
+ ++PE+ L L+ L+L HN ++Q ++ F TNL L L N + F
Sbjct 70 NLVTIKPEMFVNLSRLQCLSLSHNSIAQAVNGSQFLPLTNLQVLDLSHNKLDLYHWKSFS 129
Query 145 KQKNLITLDLSHNG--LSSTKLGTQ----VQLENLQELLLSNNKIQALKSEELDIFANSS 198
+ L LDLS+N +G L LQ L L++N I S L+ ++S
Sbjct 130 ELPQLQALDLSYNSQPFXXXXIGHNFSFVTHLSMLQSLSLAHNDIHTRVSSHLN---SNS 186
Query 199 LKKLELSSNQIKEFSPGCFHAIGRLF---GLFLNNVQLGPSLTEKLCLELANTSIRNLSL 255
++ L+ S N +GR++ GL+L+ Q L+ L L+L+ ++ L
Sbjct 187 VRFLDFSGN-----------GMGRMWDEGGLYLHFFQ---GLSGLLKLDLSQNNLHILRP 232
Query 256 SN------SQLSTTSNTTFLG-LKWT------NLTMLDLSYNNLNVVGNDSF 294
N S + +L WT NL +LDL+ N L + N +
Sbjct 233 QNLDNLPKSLKLLSLRDNYLSFFNWTSLSFLPNLEVLDLAGNQLKALTNGTL 284
Score = 56.2 bits (134), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 99/375 (26%), Positives = 148/375 (39%), Gaps = 75/375 (20%)
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
+S L SLP F L L L++ N++ IK MF L L+ LSLS++ + +
Sbjct 43 ESNKLQSLPH---GVFDKLTQLTKLSLSRNNLVTIKPEMFVNLSRLQCLSLSHNSIA-QA 98
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE-------IGQELT 448
+ F+ L + L +L+L+ NK+ +FS L L+ LDL N IG +
Sbjct 99 VNGSQFLPLTN--LQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSQPFXXXXIGHNFS 156
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP------- 501
F +LS + L L N S L +++ +D S +
Sbjct 157 ----------FVTHLSMLQSLSLAHNDIHTRVSSH---LNSNSVRFLDFSGNGMGRMWDE 203
Query 502 -------FQPLRNLTILDLSNNNIANINDDMLEG-------------------------L 529
FQ L L LDLS NN+ + L+ L
Sbjct 204 GGLYLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLKLLSLRDNYLSFFNWTSLSFL 263
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
LE+LDL N L L P G + L L++ SN + F ELK
Sbjct 264 PNLEVLDLAGNQLKALTNGTLPNGTL--------LQKLDVSSNSIVSVVPAFFALAVELK 315
Query 590 IIDLGLNNLNTLPAS-VFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
++L N L T+ S LK L L N + SV +F +L ++ + NP+D
Sbjct 316 EVNLSHNILKTVDRSWXXXXXXXLKELALDTNQLKSVPDGIFD-XXTSLQKIWLHTNPWD 374
Query 649 CTCESIAWFVNWINE 663
C+C I + W+N+
Sbjct 375 CSCPRIDYLSRWLNK 389
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 98/362 (27%), Positives = 159/362 (44%), Gaps = 31/362 (9%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL---NNVQLGPSLTEKLCLELANTSIRNL 253
SS +LEL SN+++ G F + +L L L N V + P + L + ++ L
Sbjct 35 SSATRLELESNKLQSLPHGVFDKLTQLTKLSLSRNNLVTIKPEMFVNL------SRLQCL 88
Query 254 SLSNSQLSTTSN-TTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
SLS++ ++ N + FL L TNL +LDLS+N L++ SF+ LPQL+ L YN+
Sbjct 89 SLSHNSIAQAVNGSQFLPL--TNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSQPF 146
Query 313 LFSHSLHGLFNVRYLNLKRSFT--KQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGI 370
H V +L++ +S + I ++ S ++L + D G+
Sbjct 147 XXXXIGHNFSFVTHLSMLQSLSLAHNDIHTRVSSHLNSNSVRFLDFSGNGMGRMWDEGGL 206
Query 371 KSNMFTGLINLKYLSLS-NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
+ F GL L L LS N+ LR + L+L N +S + S+
Sbjct 207 YLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLKL----LSLRDNYLSFFNWTSLSF 262
Query 430 LGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRR 489
L +LEVLDL N++ + LT + ++ +S N + + FAL L+ + L
Sbjct 263 LPNLEVLDLAGNQL-KALTNGTLPNGTLLQKLDVSSNSIVSVVPAFFALAVELKEVNLSH 321
Query 490 VALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHA 549
LK VD S L L L N + ++ D + + L+ ++W H
Sbjct 322 NILKTVDRSWX-XXXXXXLKELALDTNQLKSVPDGIFDXXTSLQ----------KIWLHT 370
Query 550 NP 551
NP
Sbjct 371 NP 372
Score = 39.3 bits (90), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 31/85 (36%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
L LESN +P VF L +L + L NNL T+ +F N L+ L+L N S+
Sbjct 40 LELESNKLQSLPHGVFDKLTQLTKLSLSRNNLVTIKPEMFVNLSRLQCLSLSHN---SIA 96
Query 627 KKVFGPAF---RNLTELDMRFNPFD 648
+ V G F NL LD+ N D
Sbjct 97 QAVNGSQFLPLTNLQVLDLSHNKLD 121
>1xku_A A Decorin
Length=330
Score = 68.9 bits (167), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 72/284 (25%), Positives = 112/284 (39%), Gaps = 59/284 (21%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C V CS L L +VP DLP + +L+L +N++ + +F L +L + N
Sbjct 28 RCQCHLRVVQCSDLGLEKVPKDLPPDTALLDLQNNKITEIKDGDFKNLKNLHTLILINNK 87
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
ISK+ P L L+ L L N+L +L +K L EL + N I K++ + F
Sbjct 88 ISKISPGAFAPLVKLERLYLSKNQLKELPEK---MPKTLQELRVHENEITKVRKSVFNGL 144
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+I ++L N L S+ + N Q +K L + ++
Sbjct 145 NQMIVVELGTNPLKSSG--------------IENGAFQGMK----------KLSYIRIAD 180
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT 266
I G L PSLTE L L ++++
Sbjct 181 TNITTIPQG-----------------LPPSLTE-------------LHLDGNKITKVDAA 210
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNI 310
+ GL NL L LS+N+++ V N S A P L L N +
Sbjct 211 SLKGL--NNLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKL 252
Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 59/220 (27%), Positives = 95/220 (43%), Gaps = 36/220 (16%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG----------QELTGQE------- 451
LH L L NKISKI AF+ L LE L L N++ QEL E
Sbjct 78 LHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKELPEKMPKTLQELRVHENEITKVR 137
Query 452 ---WRGLENIFEIYLSYN--KYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLR 506
+ GL + + L N K + +F +++L R+A N+ + P P
Sbjct 138 KSVFNGLNQMIVVELGTNPLKSSGIENGAFQ---GMKKLSYIRIADTNITTIPQGLPP-- 192
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+LT L L N I ++ L+GL L L L N+++ + + L HL
Sbjct 193 SLTELHLDGNKITKVDAASLKGLNNLAKLGLSFNSISAVDNGS--------LANTPHLRE 244
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVF 606
L+L +N ++P D ++++ L NN++ + ++ F
Sbjct 245 LHLNNNKLVKVP-GGLADHKYIQVVYLHNNNISAIGSNDF 283
Score = 43.1 bits (100), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 56/248 (23%), Positives = 99/248 (40%), Gaps = 21/248 (8%)
Query 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQ 336
+LDL N + + + F L L L N I + + L + L L ++
Sbjct 55 ALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKN---- 110
Query 337 SISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTL 396
L LP+ + K L+ L + +N+I ++ ++F GL + + L + +
Sbjct 111 --QLKELPE------KMPKTLQELRVHENEITKVRKSVFNGLNQMIVVELGTNPLKSSGI 162
Query 397 TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLE 456
N F + L + + I+ I L L L N+I ++ +GL
Sbjct 163 ENGAFQGMKK--LSYIRIADTNITTIPQGLPPSLTELH---LDGNKI-TKVDAASLKGLN 216
Query 457 NIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
N+ ++ LS+N + S A P L+ L L L V P + + ++ L NN
Sbjct 217 NLAKLGLSFNSISAVDNGSLANTPHLRELHLNNNKLVKV---PGGLADHKYIQVVYLHNN 273
Query 517 NIANINDD 524
NI+ I +
Sbjct 274 NISAIGSN 281
Score = 42.7 bits (99), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 53/212 (25%), Positives = 92/212 (43%), Gaps = 42/212 (20%)
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
+LDL N+I E+ +++ L+N+ + L NK +++ +FA + L+RL L + LK
Sbjct 56 LLDLQNNKI-TEIKDGDFKNLKNLHTLILINNKISKISPGAFAPLVKLERLYLSKNQLKE 114
Query 495 V-DSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG 553
+ + P Q LR + N I + + GL ++ +++L NP
Sbjct 115 LPEKMPKTLQELR------VHENEITKVRKSVFNGLNQMIVVELG----------TNP-- 156
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
L+S+G + + K L ++I D N+ T+P + SL
Sbjct 157 ---------------LKSSGIENGAFQGMKKLSYIRIAD---TNITTIPQGL---PPSLT 195
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L+L N IT V+ NL +L + FN
Sbjct 196 ELHLDGNKITKVDAASLK-GLNNLAKLGLSFN 226
Score = 35.0 bits (79), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
+LDL NN I I D + L+ L L L +N ++++ +PG L L L
Sbjct 55 ALLDLQNNKITEIKDGDFKNLKNLHTLILINNKISKI----SPGA----FAPLVKLERLY 106
Query 569 LESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
L N E+P ++ K L EL++ + N + + SVFN
Sbjct 107 LSKNQLKELPEKMPKTLQELRVHE---NEITKVRKSVFN 142
>5lfn_C C Chondroadherin
Length=337
Score = 68.9 bits (167), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 110/230 (48%), Gaps = 11/230 (5%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L+L H Q+R + A F QL L + N I L L L L L HN++
Sbjct 54 NLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKV 113
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
++L + NL L L +N I++++ F K+L L LS N LSS + G +E
Sbjct 114 TELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVE 173
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGR-LFGLFLNN 230
NL + + N++ + S L +++L+LS N +K F + GR L L+L+N
Sbjct 174 NLAKFHVDRNQLSSYPSAALSKL--RVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 231
Query 231 VQLGPSLTEKLC--LELANTSIRNLSLSNSQLST-TSNTTFLGLKWTNLT 277
L EK L T+++++ L N++L+ SN F L+ LT
Sbjct 232 TNL-----EKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDSLETLALT 276
Score = 66.2 bits (160), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 67/240 (28%), Positives = 113/240 (47%), Gaps = 12/240 (5%)
Query 96 QKLPML----KVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
QK+P + K+LNLQ N L+ +F NL LHL I+++ F K LI
Sbjct 22 QKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIY 81
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
L LSHN + + G L L L L +NK+ L L N L L+L++N+I+E
Sbjct 82 LYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVN--LFILQLNNNKIRE 139
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
G F L L+L+ L SL ++ N + + +QLS+ + L
Sbjct 140 LRAGAFQGAKDLRWLYLSENALS-SLQPGALDDVEN--LAKFHVDRNQLSSYPSAALSKL 196
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQ-LEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
+ + L LS+N L + +++F + LE +L+ N++ + G+ +++++L+
Sbjct 197 RV--VEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLE 254
Score = 62.4 bits (150), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 75/304 (25%), Positives = 122/304 (40%), Gaps = 37/304 (12%)
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
+LNL +N + +++F + +L L L +I +E+ +RGL+ + +YLS+N
Sbjct 33 LLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQI-REVAAGAFRGLKQLIYLYLSHNDIRV 91
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
L +F + L L L + + PL NL IL L+NN I + +G +
Sbjct 92 LRAGAFDDLTELTYLYLDHNKVTELPRGL--LSPLVNLFILQLNNNKIRELRAGAFQGAK 149
Query 531 KLEILDLQHNNLARLWKHANPGG--------------------PIYFLKGLSHLHILNLE 570
L L L N L+ L PG P L L + L L
Sbjct 150 DLRWLYLSENALSSL----QPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLS 205
Query 571 SNGFDEIPVEVFKDLFE-LKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
N IP F+ L+ + L NL F +LK ++L+ N + +
Sbjct 206 HNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNF 265
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
F +L L + NP+ CTC+ + W+ E + P+ + C +P + G +R
Sbjct 266 ---PFDSLETLALTNNPWKCTCQ-LRGLRRWL-EAKASRPDAT----CASPAKFKGQHIR 316
Query 690 LFDT 693
D
Sbjct 317 DTDA 320
Score = 55.1 bits (131), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 69/256 (27%), Positives = 120/256 (47%), Gaps = 25/256 (10%)
Query 324 VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
+ LNL+R+ + P + SF+ + L L+++ I + + F GL L Y
Sbjct 31 TKLLNLQRN---------NFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIY 81
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L LS++ +R L F L + L L L NK++++ S L +L +L L N+I
Sbjct 82 LYLSHN--DIRVLRAGAFDDL--TELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKI 137
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
+EL ++G +++ +YLS N L + V +L + + R L + S +
Sbjct 138 -RELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPS--AALS 194
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
LR + L LS+N + +I D+ + + LE L L + NL + G + L
Sbjct 195 KLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKF-----SDGAFLGVTTLK 249
Query 563 HLHILNLESNGFDEIP 578
H+H LE+N +++P
Sbjct 250 HVH---LENNRLNQLP 262
Score = 52.4 bits (124), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 57/220 (26%), Positives = 92/220 (42%), Gaps = 6/220 (3%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
+ +P L L+LQH ++ +++ F L L+L N I+ ++ F L L L
Sbjct 50 RAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLD 109
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
HN ++ G L NL L L+NNKI+ L++ L+ L LS N + PG
Sbjct 110 HNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQ--GAKDLRWLYLSENALSSLQPG 167
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTN 275
+ L ++ QL + L + L LS++ L + + F
Sbjct 168 ALDDVENLAKFHVDRNQLSSYPSAALS---KLRVVEELKLSHNPLKSIPDNAFQSFG-RY 223
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFS 315
L L L NL + +F + L++ LE N + L S
Sbjct 224 LETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPS 263
Score = 43.9 bits (102), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 47/187 (25%), Positives = 79/187 (42%), Gaps = 26/187 (14%)
Query 47 DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNL 106
DDL T +T L L HN++ LP L L L +L L
Sbjct 98 DDL-TELTYLYLDHNKVTELPRG------------------------LLSPLVNLFILQL 132
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGT 166
+N++ +L F +L L+L N++ ++ +NL + N LSS
Sbjct 133 NNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAA 192
Query 167 QVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGL 226
+L ++EL LS+N ++++ F L+ L L + +++FS G F + L +
Sbjct 193 LSKLRVVEELKLSHNPLKSIPDNAFQSFGR-YLETLWLDNTNLEKFSDGAFLGVTTLKHV 251
Query 227 FLNNVQL 233
L N +L
Sbjct 252 HLENNRL 258
Score = 35.8 bits (81), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 48/103 (47%), Gaps = 8/103 (8%)
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
EK ++L+LQ NN L ++ + + +L L+L+ E+ F+ L +L
Sbjct 29 EKTKLLNLQRNNFPVLAANS--------FRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 80
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP 632
+ L N++ L A F++ L L L N +T + + + P
Sbjct 81 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSP 123
>5lfn_B B Chondroadherin
Length=337
Score = 68.9 bits (167), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 110/230 (48%), Gaps = 11/230 (5%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L+L H Q+R + A F QL L + N I L L L L L HN++
Sbjct 54 NLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKV 113
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
++L + NL L L +N I++++ F K+L L LS N LSS + G +E
Sbjct 114 TELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVE 173
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGR-LFGLFLNN 230
NL + + N++ + S L +++L+LS N +K F + GR L L+L+N
Sbjct 174 NLAKFHVDRNQLSSYPSAALSKL--RVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 231
Query 231 VQLGPSLTEKLCLE--LANTSIRNLSLSNSQLST-TSNTTFLGLKWTNLT 277
L EK L T+++++ L N++L+ SN F L+ LT
Sbjct 232 TNL-----EKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDSLETLALT 276
Score = 66.2 bits (160), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 67/240 (28%), Positives = 113/240 (47%), Gaps = 12/240 (5%)
Query 96 QKLPML----KVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
QK+P + K+LNLQ N L+ +F NL LHL I+++ F K LI
Sbjct 22 QKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIY 81
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
L LSHN + + G L L L L +NK+ L L N L L+L++N+I+E
Sbjct 82 LYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVN--LFILQLNNNKIRE 139
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
G F L L+L+ L SL ++ N + + +QLS+ + L
Sbjct 140 LRAGAFQGAKDLRWLYLSENALS-SLQPGALDDVEN--LAKFHVDRNQLSSYPSAALSKL 196
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQ-LEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
+ + L LS+N L + +++F + LE +L+ N++ + G+ +++++L+
Sbjct 197 RV--VEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLE 254
Score = 62.8 bits (151), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 77/308 (25%), Positives = 124/308 (40%), Gaps = 38/308 (12%)
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
+LNL +N + +++F + +L L L +I +E+ +RGL+ + +YLS+N
Sbjct 33 LLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQI-REVAAGAFRGLKQLIYLYLSHNDIRV 91
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
L +F + L L L + + PL NL IL L+NN I + +G +
Sbjct 92 LRAGAFDDLTELTYLYLDHNKVTELPRGL--LSPLVNLFILQLNNNKIRELRAGAFQGAK 149
Query 531 KLEILDLQHNNLARLWKHANPGG--------------------PIYFLKGLSHLHILNLE 570
L L L N L+ L PG P L L + L L
Sbjct 150 DLRWLYLSENALSSL----QPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLS 205
Query 571 SNGFDEIPVEVFKDLFE-LKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
N IP F+ L+ + L NL F +LK ++L+ N + +
Sbjct 206 HNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNF 265
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
F +L L + NP+ CTC+ + W+ E + P+ + C +P + G +R
Sbjct 266 ---PFDSLETLALTNNPWKCTCQ-LRGLRRWL-EAKASRPDAT----CASPAKFKGQHIR 316
Query 690 LFDT-SSC 696
D SC
Sbjct 317 DTDAFRSC 324
Score = 55.5 bits (132), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 69/256 (27%), Positives = 120/256 (47%), Gaps = 25/256 (10%)
Query 324 VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
+ LNL+R+ + P + SF+ + L L+++ I + + F GL L Y
Sbjct 31 TKLLNLQRN---------NFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIY 81
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L LS++ +R L F L + L L L NK++++ S L +L +L L N+I
Sbjct 82 LYLSHN--DIRVLRAGAFDDL--TELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKI 137
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
+EL ++G +++ +YLS N L + V +L + + R L + S +
Sbjct 138 -RELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPS--AALS 194
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
LR + L LS+N + +I D+ + + LE L L + NL + G + L
Sbjct 195 KLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKF-----SDGAFLGVTTLK 249
Query 563 HLHILNLESNGFDEIP 578
H+H LE+N +++P
Sbjct 250 HVH---LENNRLNQLP 262
Score = 52.4 bits (124), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 57/220 (26%), Positives = 92/220 (42%), Gaps = 6/220 (3%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
+ +P L L+LQH ++ +++ F L L+L N I+ ++ F L L L
Sbjct 50 RAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLD 109
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
HN ++ G L NL L L+NNKI+ L++ L+ L LS N + PG
Sbjct 110 HNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQ--GAKDLRWLYLSENALSSLQPG 167
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTN 275
+ L ++ QL + L + L LS++ L + + F
Sbjct 168 ALDDVENLAKFHVDRNQLSSYPSAALS---KLRVVEELKLSHNPLKSIPDNAFQSFG-RY 223
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFS 315
L L L NL + +F + L++ LE N + L S
Sbjct 224 LETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPS 263
Score = 43.9 bits (102), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 47/187 (25%), Positives = 79/187 (42%), Gaps = 26/187 (14%)
Query 47 DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNL 106
DDL T +T L L HN++ LP L L L +L L
Sbjct 98 DDL-TELTYLYLDHNKVTELPRG------------------------LLSPLVNLFILQL 132
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGT 166
+N++ +L F +L L+L N++ ++ +NL + N LSS
Sbjct 133 NNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAA 192
Query 167 QVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGL 226
+L ++EL LS+N ++++ F L+ L L + +++FS G F + L +
Sbjct 193 LSKLRVVEELKLSHNPLKSIPDNAFQSFGR-YLETLWLDNTNLEKFSDGAFLGVTTLKHV 251
Query 227 FLNNVQL 233
L N +L
Sbjct 252 HLENNRL 258
Score = 35.8 bits (81), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 48/103 (47%), Gaps = 8/103 (8%)
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
EK ++L+LQ NN L ++ + + +L L+L+ E+ F+ L +L
Sbjct 29 EKTKLLNLQRNNFPVLAANS--------FRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 80
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP 632
+ L N++ L A F++ L L L N +T + + + P
Sbjct 81 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSP 123
>5lfn_A A Chondroadherin
Length=337
Score = 68.9 bits (167), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 110/230 (48%), Gaps = 11/230 (5%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L+L H Q+R + A F QL L + N I L L L L L HN++
Sbjct 54 NLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKV 113
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
++L + NL L L +N I++++ F K+L L LS N LSS + G +E
Sbjct 114 TELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVE 173
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGR-LFGLFLNN 230
NL + + N++ + S L +++L+LS N +K F + GR L L+L+N
Sbjct 174 NLAKFHVDRNQLSSYPSAALSKL--RVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 231
Query 231 VQLGPSLTEKLCLE--LANTSIRNLSLSNSQLST-TSNTTFLGLKWTNLT 277
L EK L T+++++ L N++L+ SN F L+ LT
Sbjct 232 TNL-----EKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDSLETLALT 276
Score = 66.2 bits (160), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 67/240 (28%), Positives = 113/240 (47%), Gaps = 12/240 (5%)
Query 96 QKLPML----KVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
QK+P + K+LNLQ N L+ +F NL LHL I+++ F K LI
Sbjct 22 QKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIY 81
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
L LSHN + + G L L L L +NK+ L L N L L+L++N+I+E
Sbjct 82 LYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVN--LFILQLNNNKIRE 139
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
G F L L+L+ L SL ++ N + + +QLS+ + L
Sbjct 140 LRAGAFQGAKDLRWLYLSENALS-SLQPGALDDVEN--LAKFHVDRNQLSSYPSAALSKL 196
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQ-LEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
+ + L LS+N L + +++F + LE +L+ N++ + G+ +++++L+
Sbjct 197 RV--VEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLE 254
Score = 62.8 bits (151), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 77/308 (25%), Positives = 124/308 (40%), Gaps = 38/308 (12%)
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
+LNL +N + +++F + +L L L +I +E+ +RGL+ + +YLS+N
Sbjct 33 LLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQI-REVAAGAFRGLKQLIYLYLSHNDIRV 91
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
L +F + L L L + + PL NL IL L+NN I + +G +
Sbjct 92 LRAGAFDDLTELTYLYLDHNKVTELPRGL--LSPLVNLFILQLNNNKIRELRAGAFQGAK 149
Query 531 KLEILDLQHNNLARLWKHANPGG--------------------PIYFLKGLSHLHILNLE 570
L L L N L+ L PG P L L + L L
Sbjct 150 DLRWLYLSENALSSL----QPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLS 205
Query 571 SNGFDEIPVEVFKDLFE-LKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
N IP F+ L+ + L NL F +LK ++L+ N + +
Sbjct 206 HNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNF 265
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
F +L L + NP+ CTC+ + W+ E + P+ + C +P + G +R
Sbjct 266 ---PFDSLETLALTNNPWKCTCQ-LRGLRRWL-EAKASRPDAT----CASPAKFKGQHIR 316
Query 690 LFDT-SSC 696
D SC
Sbjct 317 DTDAFRSC 324
Score = 55.5 bits (132), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 69/256 (27%), Positives = 120/256 (47%), Gaps = 25/256 (10%)
Query 324 VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
+ LNL+R+ + P + SF+ + L L+++ I + + F GL L Y
Sbjct 31 TKLLNLQRN---------NFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIY 81
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L LS++ +R L F L + L L L NK++++ S L +L +L L N+I
Sbjct 82 LYLSHN--DIRVLRAGAFDDL--TELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKI 137
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
+EL ++G +++ +YLS N L + V +L + + R L + S +
Sbjct 138 -RELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPS--AALS 194
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
LR + L LS+N + +I D+ + + LE L L + NL + G + L
Sbjct 195 KLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKF-----SDGAFLGVTTLK 249
Query 563 HLHILNLESNGFDEIP 578
H+H LE+N +++P
Sbjct 250 HVH---LENNRLNQLP 262
Score = 52.4 bits (124), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 57/220 (26%), Positives = 92/220 (42%), Gaps = 6/220 (3%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
+ +P L L+LQH ++ +++ F L L+L N I+ ++ F L L L
Sbjct 50 RAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLD 109
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
HN ++ G L NL L L+NNKI+ L++ L+ L LS N + PG
Sbjct 110 HNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQ--GAKDLRWLYLSENALSSLQPG 167
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTN 275
+ L ++ QL + L + L LS++ L + + F
Sbjct 168 ALDDVENLAKFHVDRNQLSSYPSAALS---KLRVVEELKLSHNPLKSIPDNAFQSFG-RY 223
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFS 315
L L L NL + +F + L++ LE N + L S
Sbjct 224 LETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPS 263
Score = 43.9 bits (102), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 47/187 (25%), Positives = 79/187 (42%), Gaps = 26/187 (14%)
Query 47 DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNL 106
DDL T +T L L HN++ LP L L L +L L
Sbjct 98 DDL-TELTYLYLDHNKVTELPRG------------------------LLSPLVNLFILQL 132
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGT 166
+N++ +L F +L L+L N++ ++ +NL + N LSS
Sbjct 133 NNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAA 192
Query 167 QVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGL 226
+L ++EL LS+N ++++ F L+ L L + +++FS G F + L +
Sbjct 193 LSKLRVVEELKLSHNPLKSIPDNAFQSFGR-YLETLWLDNTNLEKFSDGAFLGVTTLKHV 251
Query 227 FLNNVQL 233
L N +L
Sbjct 252 HLENNRL 258
Score = 35.8 bits (81), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 48/103 (47%), Gaps = 8/103 (8%)
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
EK ++L+LQ NN L ++ + + +L L+L+ E+ F+ L +L
Sbjct 29 EKTKLLNLQRNNFPVLAANS--------FRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 80
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP 632
+ L N++ L A F++ L L L N +T + + + P
Sbjct 81 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSP 123
>4uip_B B REPEBODY (RAC1)
Length=251
Score = 67.4 bits (163), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 56/167 (34%), Positives = 78/167 (47%), Gaps = 12/167 (7%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
Q L N+ L L N + +I+ L+ L L L L +N L L P G L
Sbjct 60 IQYLPNVRYLALGGNKLHDIS--ALKELTNLTYLMLHYNQLQIL-----PNG---VFDKL 109
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
++L L L N +P VF L L +DL N L +LP VF+ LK L L +N
Sbjct 110 TNLKELYLSENQLQSLPDGVFDKLTNLTELDLARNQLQSLPKGVFDKLTQLKDLRLYQNQ 169
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
+ SV VF +L + + NP+DCTC I + WIN+ H+ +
Sbjct 170 LKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIRYLSEWINK-HSGV 214
Score = 55.8 bits (133), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 49/135 (36%), Positives = 67/135 (50%), Gaps = 4/135 (3%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
Q LP ++ L L N+L +S TNLT L L N +Q + N F K NL L LS
Sbjct 61 QYLPNVRYLALGGNKLHDIS--ALKELTNLTYLMLHYNQLQILPNGVFDKLTNLKELYLS 118
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L S G +L NL EL L+ N++Q+L D + LK L L NQ+K G
Sbjct 119 ENQLQSLPDGVFDKLTNLTELDLARNQLQSLPKGVFDKL--TQLKDLRLYQNQLKSVPDG 176
Query 216 CFHAIGRLFGLFLNN 230
F + L ++L++
Sbjct 177 VFDRLTSLQYIWLHD 191
Score = 53.1 bits (126), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 51/153 (33%), Positives = 71/153 (46%), Gaps = 3/153 (2%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L + +N +
Sbjct 43 SIDQIIANNSDIKSVQGIQYLP-NVRYLALGGNKLHDISA--LKELTNLTYLMLHYNQLQ 99
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLTEL L N +Q + F K
Sbjct 100 ILPNGVFDKLTNLKELYLSENQLQSLPDGVFDKLTNLTELDLARNQLQSLPKGVFDKLTQ 159
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
L L L N L S G +L +LQ + L +N
Sbjct 160 LKDLRLYQNQLKSVPDGVFDRLTSLQYIWLHDN 192
Score = 48.5 bits (114), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 39/120 (33%), Positives = 60/120 (50%), Gaps = 2/120 (2%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
++L L L L +N+L L + F TNL EL+L N +Q + + F K NL LDL+
Sbjct 83 KELTNLTYLMLHYNQLQILPNGVFDKLTNLKELYLSENQLQSLPDGVFDKLTNLTELDLA 142
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L S G +L L++L L N+++++ D +SL+ + L N PG
Sbjct 143 RNQLQSLPKGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL--TSLQYIWLHDNPWDCTCPG 200
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 42/135 (31%), Positives = 62/135 (46%), Gaps = 13/135 (10%)
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
+R L+L ++L S L TNLT L L YN L ++ N F L L+ +L N
Sbjct 66 VRYLALGGNKLHDISALKEL----TNLTYLMLHYNQLQILPNGVFDKLTNLKELYLSENQ 121
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG 369
+Q L L N+ L+L R+ L SLPK F L L+ L + N +
Sbjct 122 LQSLPDGVFDKLTNLTELDLARN------QLQSLPK---GVFDKLTQLKDLRLYQNQLKS 172
Query 370 IKSNMFTGLINLKYL 384
+ +F L +L+Y+
Sbjct 173 VPDGVFDRLTSLQYI 187
Score = 35.0 bits (79), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 5/100 (5%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L+L N++Q L + D N LK+L LS NQ++ G F + L L L
Sbjct 84 ELTNLTYLMLHYNQLQILPNGVFDKLTN--LKELYLSENQLQSLPDGVFDKLTNLTELDL 141
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
QL SL + + +L T +++L L +QL + + F
Sbjct 142 ARNQLQ-SLPKGVFDKL--TQLKDLRLYQNQLKSVPDGVF 178
>6gff_J J Leucine-rich repeat-containing protein 32
Length=618
Score = 70.1 bits (170), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 161/608 (26%), Positives = 244/608 (40%), Gaps = 102/608 (17%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C + + C L L QVP LP + L+L+ NQLR + A+ Y+ L LD+ N I
Sbjct 7 CKMVDKKVSCQVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEI 66
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
S L+P Q L L+ L+L HN L+ M+ ++ P +
Sbjct 67 SFLQPGAFQALTHLEHLSLAHNRLA------------------MATALSAGGLGPLPR-- 106
Query 148 NLITLDLSHNGLSSTKLGTQV-QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
+ +LDLS N L S L + + +L L L+ N + L +L++L+L S
Sbjct 107 -VTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMP--ALEQLDLHS 163
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGP----SLTEKLCLELANTSIRNLSLSNSQLST 262
N + + G F + RL L L+ L SL + L+L+ SI Q ++
Sbjct 164 NVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLRVLDLSCNSIEAF-----QTAS 218
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
F LT LDL N L + A LP+L Y L NN+ L
Sbjct 219 QPQAEF------QLTWLDLRENKL--LHFPDLAALPRLIYLNLS-NNLIRLPXXXXXXXX 269
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
+ + ++ +L L +L++ N+I I + L +L
Sbjct 270 XI------HAPSEGWSALXXXXXXXXXXXXXXXQLLNLDLSYNEIELIPDSFLEHLTSLC 323
Query 383 YLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE 442
+L+LS + LRT SL L +L+L+ N LE L+LG
Sbjct 324 FLNLSRN--CLRTFEARRLGSLPC--LMLLDLSHNA--------------LETLELG--- 362
Query 443 IGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLR--RVA-----LKNV 495
R L ++ + L N L +FA + SLQRL L+ RV+
Sbjct 363 ---------ARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCXXXXXXX 413
Query 496 DSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPI 555
F + +L L L +N I E L H L L +NPG +
Sbjct 414 XXXCVAFSGITSLRSLSLVDNEI-----------ELLRAGAFLHTPLTELDLSSNPGLEV 462
Query 556 Y--FLKGL-SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
L GL + L +L L+ NG + V++ LK ++L N L+ LPA + VSL
Sbjct 463 ATGALGGLEASLEVLALQGNGLMVLQVDL-PCFICLKRLNLAENRLSHLPA--WTQAVSL 519
Query 613 KSLNLQKN 620
+ L+L+ N
Sbjct 520 EVLDLRNN 527
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 80/326 (25%), Positives = 139/326 (43%), Gaps = 58/326 (18%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT-----------------LTNE 399
L HL++ N+I ++ F L +L++LSL+++ ++ T L+
Sbjct 56 LRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGN 115
Query 400 TFVS------LAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
+ S L +P LH L+L +N ++++ F + LE LDL N + ++ +
Sbjct 116 SLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVL-MDIEDGAF 174
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVP--SLQRLMLRRVALKNVDSSPSPFQPLR--NL 508
GL + +L L+RNS + SLQ+L + ++ ++++ + QP L
Sbjct 175 EGLPRL--------THLNLSRNSLTCISDFSLQQLRVLDLSCNSIEAFQTASQPQAEFQL 226
Query 509 TILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILN 568
T LDL N + + D L L +L L+L NNL RL P +H
Sbjct 227 TWLDLRENKLLHFPD--LAALPRLIYLNLS-NNLIRL--------PXXXXXXXXXIHA-- 273
Query 569 LESNGFDEI------PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLI 622
S G+ + +L +DL N + +P S + SL LNL +N +
Sbjct 274 -PSEGWSALXXXXXXXXXXXXXXXQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCL 332
Query 623 TSVEKKVFGPAFRNLTELDMRFNPFD 648
+ E + G + L LD+ N +
Sbjct 333 RTFEARRLG-SLPCLMLLDLSHNALE 357
Score = 43.1 bits (100), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 57/212 (27%), Positives = 85/212 (40%), Gaps = 35/212 (17%)
Query 467 KYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPF-QPLRNLTILDLSNNNIANINDDM 525
+ L L + L P + L L L+++ +SP F LR+L DLS N I+ +
Sbjct 17 QVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHL---DLSTNEISFLQPGA 73
Query 526 LEGLEKLEILDLQHNNLARLWKHANPG-GPIYFLKGLS-------------------HLH 565
+ L LE L L HN LA + G GP+ + L LH
Sbjct 74 FQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLH 133
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L N + F+D+ L+ +DL N L + F L LNL +N +T +
Sbjct 134 TLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCI 193
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWF 657
+ + L LD+ +C SI F
Sbjct 194 SDF----SLQQLRVLDL-------SCNSIEAF 214
>5lfn_D D Chondroadherin
Length=337
Score = 68.9 bits (167), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 110/230 (48%), Gaps = 11/230 (5%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L+L H Q+R + A F QL L + N I L L L L L HN++
Sbjct 54 NLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKV 113
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
++L + NL L L +N I++++ F K+L L LS N LSS + G +E
Sbjct 114 TELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVE 173
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGR-LFGLFLNN 230
NL + + N++ + S L +++L+LS N +K F + GR L L+L+N
Sbjct 174 NLAKFHVDRNQLSSYPSAALSKL--RVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 231
Query 231 VQLGPSLTEKLC--LELANTSIRNLSLSNSQLST-TSNTTFLGLKWTNLT 277
L EK L T+++++ L N++L+ SN F L+ LT
Sbjct 232 TNL-----EKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDSLETLALT 276
Score = 66.2 bits (160), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 67/240 (28%), Positives = 113/240 (47%), Gaps = 12/240 (5%)
Query 96 QKLPML----KVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
QK+P + K+LNLQ N L+ +F NL LHL I+++ F K LI
Sbjct 22 QKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIY 81
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
L LSHN + + G L L L L +NK+ L L N L L+L++N+I+E
Sbjct 82 LYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVN--LFILQLNNNKIRE 139
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
G F L L+L+ L SL ++ N + + +QLS+ + L
Sbjct 140 LRAGAFQGAKDLRWLYLSENALS-SLQPGALDDVEN--LAKFHVDRNQLSSYPSAALSKL 196
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQ-LEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
+ + L LS+N L + +++F + LE +L+ N++ + G+ +++++L+
Sbjct 197 RV--VEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLE 254
Score = 64.7 bits (156), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 78/309 (25%), Positives = 125/309 (40%), Gaps = 38/309 (12%)
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
+LNL +N + +++F + +L L L +I +E+ +RGL+ + +YLS+N
Sbjct 33 LLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQI-REVAAGAFRGLKQLIYLYLSHNDIRV 91
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
L +F + L L L + + PL NL IL L+NN I + +G +
Sbjct 92 LRAGAFDDLTELTYLYLDHNKVTELPRGL--LSPLVNLFILQLNNNKIRELRAGAFQGAK 149
Query 531 KLEILDLQHNNLARLWKHANPGG--------------------PIYFLKGLSHLHILNLE 570
L L L N L+ L PG P L L + L L
Sbjct 150 DLRWLYLSENALSSL----QPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLS 205
Query 571 SNGFDEIPVEVFKDLFE-LKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
N IP F+ L+ + L NL F +LK ++L+ N + +
Sbjct 206 HNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNF 265
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
F +L L + NP+ CTC+ + W+ E + P+ + C +P + G +R
Sbjct 266 ---PFDSLETLALTNNPWKCTCQ-LRGLRRWL-EAKASRPDAT----CASPAKFKGQHIR 316
Query 690 LFDT-SSCK 697
D SCK
Sbjct 317 DTDAFRSCK 325
Score = 52.4 bits (124), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 57/220 (26%), Positives = 92/220 (42%), Gaps = 6/220 (3%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
+ +P L L+LQH ++ +++ F L L+L N I+ ++ F L L L
Sbjct 50 RAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLD 109
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
HN ++ G L NL L L+NNKI+ L++ L+ L LS N + PG
Sbjct 110 HNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQ--GAKDLRWLYLSENALSSLQPG 167
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTN 275
+ L ++ QL + L + L LS++ L + + F
Sbjct 168 ALDDVENLAKFHVDRNQLSSYPSAALS---KLRVVEELKLSHNPLKSIPDNAFQSFG-RY 223
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFS 315
L L L NL + +F + L++ LE N + L S
Sbjct 224 LETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPS 263
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 47/187 (25%), Positives = 79/187 (42%), Gaps = 26/187 (14%)
Query 47 DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNL 106
DDL T +T L L HN++ LP L L L +L L
Sbjct 98 DDL-TELTYLYLDHNKVTELPRG------------------------LLSPLVNLFILQL 132
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGT 166
+N++ +L F +L L+L N++ ++ +NL + N LSS
Sbjct 133 NNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAA 192
Query 167 QVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGL 226
+L ++EL LS+N ++++ F L+ L L + +++FS G F + L +
Sbjct 193 LSKLRVVEELKLSHNPLKSIPDNAFQSFGR-YLETLWLDNTNLEKFSDGAFLGVTTLKHV 251
Query 227 FLNNVQL 233
L N +L
Sbjct 252 HLENNRL 258
Score = 35.8 bits (81), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 48/103 (47%), Gaps = 8/103 (8%)
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
EK ++L+LQ NN L ++ + + +L L+L+ E+ F+ L +L
Sbjct 29 EKTKLLNLQRNNFPVLAANS--------FRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 80
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP 632
+ L N++ L A F++ L L L N +T + + + P
Sbjct 81 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSP 123
>7crf_A A Toll-like receptor 8
Length=811
Score = 70.5 bits (171), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 189/807 (23%), Positives = 298/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXEFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 601 LPASVFNNQVSLKSLNLQKNLITSVE-KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVN 659
LP+ + SLK L+L NL+ ++ L+ L++ NPF+CTC+ I F
Sbjct 705 LPSGFLSEVSSLKHLDLSSNLLKTINXXXXXXXXXXKLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>5mx1_B B Chondroadherin
Length=342
Score = 68.9 bits (167), Expect = 6e-11, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 110/230 (48%), Gaps = 11/230 (5%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L+L H Q+R + A F QL L + N I L L L L L HN++
Sbjct 59 NLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKV 118
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
++L + NL L L +N I++++ F K+L L LS N LSS + G +E
Sbjct 119 TELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVE 178
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGR-LFGLFLNN 230
NL + + N++ + S L +++L+LS N +K F + GR L L+L+N
Sbjct 179 NLAKFHVDRNQLSSYPSAALSKL--RVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 236
Query 231 VQLGPSLTEKLC--LELANTSIRNLSLSNSQLST-TSNTTFLGLKWTNLT 277
L EK L T+++++ L N++L+ SN F L+ LT
Sbjct 237 TNL-----EKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDSLETLALT 281
Score = 66.2 bits (160), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 67/240 (28%), Positives = 113/240 (47%), Gaps = 12/240 (5%)
Query 96 QKLPML----KVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
QK+P + K+LNLQ N L+ +F NL LHL I+++ F K LI
Sbjct 27 QKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIY 86
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
L LSHN + + G L L L L +NK+ L L N L L+L++N+I+E
Sbjct 87 LYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVN--LFILQLNNNKIRE 144
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
G F L L+L+ L SL ++ N + + +QLS+ + L
Sbjct 145 LRAGAFQGAKDLRWLYLSENALS-SLQPGALDDVEN--LAKFHVDRNQLSSYPSAALSKL 201
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQ-LEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
+ + L LS+N L + +++F + LE +L+ N++ + G+ +++++L+
Sbjct 202 RV--VEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLE 259
Score = 63.2 bits (152), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 79/309 (26%), Positives = 124/309 (40%), Gaps = 40/309 (13%)
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
+LNL +N + +++F + +L L L +I +E+ +RGL+ + +YLS+N
Sbjct 38 LLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQI-REVAAGAFRGLKQLIYLYLSHNDIRV 96
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPF-QPLRNLTILDLSNNNIANINDDMLEGL 529
L +F + L L L V P PL NL IL L+NN I + +G
Sbjct 97 LRAGAFDDLTELTYLYLDH---NKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGA 153
Query 530 EKLEILDLQHNNLARLWKHANPGG--------------------PIYFLKGLSHLHILNL 569
+ L L L N L+ L PG P L L + L L
Sbjct 154 KDLRWLYLSENALSSL----QPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKL 209
Query 570 ESNGFDEIPVEVFKDLFE-LKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
N IP F+ L+ + L NL F +LK ++L+ N + +
Sbjct 210 SHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSN 269
Query 629 VFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
F +L L + NP+ CTC+ + W+ E + P+ + C +P + G +
Sbjct 270 F---PFDSLETLALTNNPWKCTCQ-LRGLRRWL-EAKASRPDAT----CASPAKFKGQHI 320
Query 689 RLFDT-SSC 696
R D SC
Sbjct 321 RDTDAFRSC 329
Score = 55.5 bits (132), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 69/256 (27%), Positives = 120/256 (47%), Gaps = 25/256 (10%)
Query 324 VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
+ LNL+R+ + P + SF+ + L L+++ I + + F GL L Y
Sbjct 36 TKLLNLQRN---------NFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIY 86
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L LS++ +R L F L + L L L NK++++ S L +L +L L N+I
Sbjct 87 LYLSHN--DIRVLRAGAFDDL--TELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKI 142
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
+EL ++G +++ +YLS N L + V +L + + R L + S +
Sbjct 143 -RELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPS--AALS 199
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
LR + L LS+N + +I D+ + + LE L L + NL + G + L
Sbjct 200 KLRVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKF-----SDGAFLGVTTLK 254
Query 563 HLHILNLESNGFDEIP 578
H+H LE+N +++P
Sbjct 255 HVH---LENNRLNQLP 267
Score = 52.4 bits (124), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 57/220 (26%), Positives = 92/220 (42%), Gaps = 6/220 (3%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
+ +P L L+LQH ++ +++ F L L+L N I+ ++ F L L L
Sbjct 55 RAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLD 114
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
HN ++ G L NL L L+NNKI+ L++ L+ L LS N + PG
Sbjct 115 HNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQ--GAKDLRWLYLSENALSSLQPG 172
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTN 275
+ L ++ QL + L + L LS++ L + + F
Sbjct 173 ALDDVENLAKFHVDRNQLSSYPSAALS---KLRVVEELKLSHNPLKSIPDNAFQSFG-RY 228
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFS 315
L L L NL + +F + L++ LE N + L S
Sbjct 229 LETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPS 268
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 47/187 (25%), Positives = 79/187 (42%), Gaps = 26/187 (14%)
Query 47 DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNL 106
DDL T +T L L HN++ LP L L L +L L
Sbjct 103 DDL-TELTYLYLDHNKVTELPRG------------------------LLSPLVNLFILQL 137
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGT 166
+N++ +L F +L L+L N++ ++ +NL + N LSS
Sbjct 138 NNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAA 197
Query 167 QVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGL 226
+L ++EL LS+N ++++ F L+ L L + +++FS G F + L +
Sbjct 198 LSKLRVVEELKLSHNPLKSIPDNAFQSFGR-YLETLWLDNTNLEKFSDGAFLGVTTLKHV 256
Query 227 FLNNVQL 233
L N +L
Sbjct 257 HLENNRL 263
Score = 35.8 bits (81), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 48/103 (47%), Gaps = 8/103 (8%)
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
EK ++L+LQ NN L ++ + + +L L+L+ E+ F+ L +L
Sbjct 34 EKTKLLNLQRNNFPVLAANS--------FRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 85
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP 632
+ L N++ L A F++ L L L N +T + + + P
Sbjct 86 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSP 128
>5mx1_A A Chondroadherin
Length=342
Score = 68.6 bits (166), Expect = 7e-11, Method: Compositional matrix adjust.
Identities = 70/230 (30%), Positives = 110/230 (48%), Gaps = 11/230 (5%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L+L H Q+R + A F QL L + N I L L L L L HN++
Sbjct 59 NLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKV 118
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
++L + NL L L +N I++++ F K+L L LS N LSS + G +E
Sbjct 119 TELPRGLLSPLVNLFILQLNNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVE 178
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGR-LFGLFLNN 230
NL + + N++ + S L +++L+LS N +K F + GR L L+L+N
Sbjct 179 NLAKFHVDRNQLSSYPSAALSKL--RVVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDN 236
Query 231 VQLGPSLTEKLC--LELANTSIRNLSLSNSQLST-TSNTTFLGLKWTNLT 277
L EK L T+++++ L N++L+ SN F L+ LT
Sbjct 237 TNL-----EKFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDSLETLALT 281
Score = 66.2 bits (160), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 67/240 (28%), Positives = 113/240 (47%), Gaps = 12/240 (5%)
Query 96 QKLPML----KVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
QK+P + K+LNLQ N L+ +F NL LHL I+++ F K LI
Sbjct 27 QKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRGLKQLIY 86
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
L LSHN + + G L L L L +NK+ L L N L L+L++N+I+E
Sbjct 87 LYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVN--LFILQLNNNKIRE 144
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL 271
G F L L+L+ L SL ++ N + + +QLS+ + L
Sbjct 145 LRAGAFQGAKDLRWLYLSENALS-SLQPGALDDVEN--LAKFHVDRNQLSSYPSAALSKL 201
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQ-LEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
+ + L LS+N L + +++F + LE +L+ N++ + G+ +++++L+
Sbjct 202 RV--VEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLE 259
Score = 64.7 bits (156), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 78/309 (25%), Positives = 125/309 (40%), Gaps = 38/309 (12%)
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
+LNL +N + +++F + +L L L +I +E+ +RGL+ + +YLS+N
Sbjct 38 LLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQI-REVAAGAFRGLKQLIYLYLSHNDIRV 96
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
L +F + L L L + + PL NL IL L+NN I + +G +
Sbjct 97 LRAGAFDDLTELTYLYLDHNKVTELPRGL--LSPLVNLFILQLNNNKIRELRAGAFQGAK 154
Query 531 KLEILDLQHNNLARLWKHANPGG--------------------PIYFLKGLSHLHILNLE 570
L L L N L+ L PG P L L + L L
Sbjct 155 DLRWLYLSENALSSL----QPGALDDVENLAKFHVDRNQLSSYPSAALSKLRVVEELKLS 210
Query 571 SNGFDEIPVEVFKDLFE-LKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
N IP F+ L+ + L NL F +LK ++L+ N + +
Sbjct 211 HNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPSNF 270
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
F +L L + NP+ CTC+ + W+ E + P+ + C +P + G +R
Sbjct 271 ---PFDSLETLALTNNPWKCTCQ-LRGLRRWL-EAKASRPDAT----CASPAKFKGQHIR 321
Query 690 LFDT-SSCK 697
D SCK
Sbjct 322 DTDAFRSCK 330
Score = 52.4 bits (124), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 57/220 (26%), Positives = 92/220 (42%), Gaps = 6/220 (3%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
+ +P L L+LQH ++ +++ F L L+L N I+ ++ F L L L
Sbjct 55 RAMPNLVSLHLQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLD 114
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
HN ++ G L NL L L+NNKI+ L++ L+ L LS N + PG
Sbjct 115 HNKVTELPRGLLSPLVNLFILQLNNNKIRELRAGAFQ--GAKDLRWLYLSENALSSLQPG 172
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTN 275
+ L ++ QL + L + L LS++ L + + F
Sbjct 173 ALDDVENLAKFHVDRNQLSSYPSAALS---KLRVVEELKLSHNPLKSIPDNAFQSFG-RY 228
Query 276 LTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFS 315
L L L NL + +F + L++ LE N + L S
Sbjct 229 LETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNRLNQLPS 268
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 47/187 (25%), Positives = 79/187 (42%), Gaps = 26/187 (14%)
Query 47 DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNL 106
DDL T +T L L HN++ LP L L L +L L
Sbjct 103 DDL-TELTYLYLDHNKVTELPRG------------------------LLSPLVNLFILQL 137
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGT 166
+N++ +L F +L L+L N++ ++ +NL + N LSS
Sbjct 138 NNNKIRELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQLSSYPSAA 197
Query 167 QVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGL 226
+L ++EL LS+N ++++ F L+ L L + +++FS G F + L +
Sbjct 198 LSKLRVVEELKLSHNPLKSIPDNAFQSFGR-YLETLWLDNTNLEKFSDGAFLGVTTLKHV 256
Query 227 FLNNVQL 233
L N +L
Sbjct 257 HLENNRL 263
Score = 35.8 bits (81), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 26/103 (25%), Positives = 48/103 (47%), Gaps = 8/103 (8%)
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
EK ++L+LQ NN L ++ + + +L L+L+ E+ F+ L +L
Sbjct 34 EKTKLLNLQRNNFPVLAANS--------FRAMPNLVSLHLQHCQIREVAAGAFRGLKQLI 85
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP 632
+ L N++ L A F++ L L L N +T + + + P
Sbjct 86 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSP 128
>3m19_A A Variable lymphocyte receptor A diversity region
Length=251
Score = 67.0 bits (162), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C + DC L VP +P + L+L L L A F ++LT L++ +N +
Sbjct 12 CNEGKKEVDCQGKSLDSVPSGIPADTEKLDLQSTGLATLSDATFRGLTKLTWLNLDYNQL 71
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
L + L L L L +N+L+ L F T L +L+L N ++ + + F +
Sbjct 72 QTLSAGVFDDLTELGTLGLANNQLASLPLGVFDHLTQLDKLYLGGNQLKSLPSGVFDRLT 131
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
L L L+ N L S G +L NLQ L LS N++Q++ D L+ + L N
Sbjct 132 KLKELRLNTNQLQSIPAGAFDKLTNLQTLSLSTNQLQSVPHGAFDRLGK--LQTITLFGN 189
Query 208 Q 208
Q
Sbjct 190 Q 190
Score = 63.9 bits (154), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 57/211 (27%), Positives = 84/211 (40%), Gaps = 33/211 (16%)
Query 493 KNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPG 552
K++DS PS + LDL + +A ++D GL KL L+L +N L L
Sbjct 24 KSLDSVPSGIPA--DTEKLDLQSTGLATLSDATFRGLTKLTWLNLDYNQLQTL------- 74
Query 553 GPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
L+ L L L +N +P+ VF L +L + LG N L +LP+ VF+ L
Sbjct 75 -SAGVFDDLTELGTLGLANNQLASLPLGVFDHLTQLDKLYLGGNQLKSLPSGVFDRLTKL 133
Query 613 KSLNLQKNLITSVEKKVFGP--------------------AFRNLTELD---MRFNPFDC 649
K L L N + S+ F AF L +L + N FDC
Sbjct 134 KELRLNTNQLQSIPAGAFDKLTNLQTLSLSTNQLQSVPHGAFDRLGKLQTITLFGNQFDC 193
Query 650 TCESIAWFVNWINETHTNIPELSSHYLCNTP 680
+ I + WI E + + +P
Sbjct 194 SRCEILYLSQWIRENSNKVKDXXXXXXXESP 224
Score = 46.6 bits (109), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 45/160 (28%), Positives = 73/160 (46%), Gaps = 13/160 (8%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDL L + + +F L +L + L+YN +Q L + L + L L +
Sbjct 40 LDLQSTGLATLSDATFRGLTKLTWLNLDYNQLQTLSAGVFDDLTELGTLGLANN------ 93
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
LASLP F L L+ L + N + + S +F L LK L L+ + L+++
Sbjct 94 QLASLPL---GVFDHLTQLDKLYLGGNQLKSLPSGVFDRLTKLKELRLNTN--QLQSIPA 148
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDL 438
F L + L L+L+ N++ + AF LG L+ + L
Sbjct 149 GAFDKLTN--LQTLSLSTNQLQSVPHGAFDRLGKLQTITL 186
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 52/166 (31%), Positives = 73/166 (44%), Gaps = 31/166 (19%)
Query 104 LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTK 163
L+LQ L+ LSD TF T LT L+L N +Q + F L TL L++N L+S
Sbjct 40 LDLQSTGLATLSDATFRGLTKLTWLNLDYNQLQTLSAGVFDDLTELGTLGLANNQLASLP 99
Query 164 LGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGR 222
LG +F + + L KL L NQ+K G F + +
Sbjct 100 LG---------------------------VFDHLTQLDKLYLGGNQLKSLPSGVFDRLTK 132
Query 223 LFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
L L LN QL S+ +L N ++ LSLS +QL + + F
Sbjct 133 LKELRLNTNQL-QSIPAGAFDKLTN--LQTLSLSTNQLQSVPHGAF 175
Score = 39.3 bits (90), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 8/152 (5%)
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
QS LA+L D +F+ L L LN++ N + + + +F L L L L+N+ L +
Sbjct 43 QSTGLATLS---DATFRGLTKLTWLNLDYNQLQTLSAGVFDDLTELGTLGLANN--QLAS 97
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
L F L L L L N++ + S F L L+ L L N++ Q + + L
Sbjct 98 LPLGVFDHLTQ--LDKLYLGGNQLKSLPSGVFDRLTKLKELRLNTNQL-QSIPAGAFDKL 154
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
N+ + LS N+ + +F + LQ + L
Sbjct 155 TNLQTLSLSTNQLQSVPHGAFDRLGKLQTITL 186
>3m19_B B Variable lymphocyte receptor A diversity region
Length=251
Score = 67.0 bits (162), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C + DC L VP +P + L+L L L A F ++LT L++ +N +
Sbjct 12 CNEGKKEVDCQGKSLDSVPSGIPADTEKLDLQSTGLATLSDATFRGLTKLTWLNLDYNQL 71
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
L + L L L L +N+L+ L F T L +L+L N ++ + + F +
Sbjct 72 QTLSAGVFDDLTELGTLGLANNQLASLPLGVFDHLTQLDKLYLGGNQLKSLPSGVFDRLT 131
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
L L L+ N L S G +L NLQ L LS N++Q++ D L+ + L N
Sbjct 132 KLKELRLNTNQLQSIPAGAFDKLTNLQTLSLSTNQLQSVPHGAFDRLGK--LQTITLFGN 189
Query 208 Q 208
Q
Sbjct 190 Q 190
Score = 63.9 bits (154), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 57/211 (27%), Positives = 84/211 (40%), Gaps = 33/211 (16%)
Query 493 KNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPG 552
K++DS PS + LDL + +A ++D GL KL L+L +N L L
Sbjct 24 KSLDSVPSGIPA--DTEKLDLQSTGLATLSDATFRGLTKLTWLNLDYNQLQTL------- 74
Query 553 GPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
L+ L L L +N +P+ VF L +L + LG N L +LP+ VF+ L
Sbjct 75 -SAGVFDDLTELGTLGLANNQLASLPLGVFDHLTQLDKLYLGGNQLKSLPSGVFDRLTKL 133
Query 613 KSLNLQKNLITSVEKKVFGP--------------------AFRNLTELD---MRFNPFDC 649
K L L N + S+ F AF L +L + N FDC
Sbjct 134 KELRLNTNQLQSIPAGAFDKLTNLQTLSLSTNQLQSVPHGAFDRLGKLQTITLFGNQFDC 193
Query 650 TCESIAWFVNWINETHTNIPELSSHYLCNTP 680
+ I + WI E + + +P
Sbjct 194 SRCEILYLSQWIRENSNKVKDXXXXXXXESP 224
Score = 46.6 bits (109), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 45/160 (28%), Positives = 73/160 (46%), Gaps = 13/160 (8%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDL L + + +F L +L + L+YN +Q L + L + L L +
Sbjct 40 LDLQSTGLATLSDATFRGLTKLTWLNLDYNQLQTLSAGVFDDLTELGTLGLANN------ 93
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
LASLP F L L+ L + N + + S +F L LK L L+ + L+++
Sbjct 94 QLASLPL---GVFDHLTQLDKLYLGGNQLKSLPSGVFDRLTKLKELRLNTN--QLQSIPA 148
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDL 438
F L + L L+L+ N++ + AF LG L+ + L
Sbjct 149 GAFDKLTN--LQTLSLSTNQLQSVPHGAFDRLGKLQTITL 186
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 52/166 (31%), Positives = 73/166 (44%), Gaps = 31/166 (19%)
Query 104 LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTK 163
L+LQ L+ LSD TF T LT L+L N +Q + F L TL L++N L+S
Sbjct 40 LDLQSTGLATLSDATFRGLTKLTWLNLDYNQLQTLSAGVFDDLTELGTLGLANNQLASLP 99
Query 164 LGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGR 222
LG +F + + L KL L NQ+K G F + +
Sbjct 100 LG---------------------------VFDHLTQLDKLYLGGNQLKSLPSGVFDRLTK 132
Query 223 LFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
L L LN QL S+ +L N ++ LSLS +QL + + F
Sbjct 133 LKELRLNTNQL-QSIPAGAFDKLTN--LQTLSLSTNQLQSVPHGAF 175
Score = 39.3 bits (90), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 8/152 (5%)
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
QS LA+L D +F+ L L LN++ N + + + +F L L L L+N+ L +
Sbjct 43 QSTGLATLS---DATFRGLTKLTWLNLDYNQLQTLSAGVFDDLTELGTLGLANN--QLAS 97
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
L F L L L L N++ + S F L L+ L L N++ Q + + L
Sbjct 98 LPLGVFDHLTQ--LDKLYLGGNQLKSLPSGVFDRLTKLKELRLNTNQL-QSIPAGAFDKL 154
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
N+ + LS N+ + +F + LQ + L
Sbjct 155 TNLQTLSLSTNQLQSVPHGAFDRLGKLQTITL 186
>2z66_A A Variable lymphocyte receptor B, Toll-like receptor 4
Length=306
Score = 67.8 bits (164), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 76/281 (27%), Positives = 125/281 (44%), Gaps = 18/281 (6%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG-QELTGQEWRGLENIFEIYLSYNKYLQ 470
L L NK+ + F L L L L N + + Q G ++ + LS+N +
Sbjct 33 LELESNKLQSLPHGVFDKLTQLTKLSLSSNGLSFKGCCSQSDFGTTSLKYLDLSFNGVIT 92
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
++ N F + L+ L + LK + S S F LRNL LD+S+ + + + GL
Sbjct 93 MSSN-FLGLEQLEHLDFQHSNLKQM-SEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLS 150
Query 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKI 590
LE+L + N+ + P F + L +L L+L +++ F L L++
Sbjct 151 SLEVLKMAGNSFQENFL------PDIFTE-LRNLTFLDLSQCQLEQLSPTAFNSLSSLQV 203
Query 591 IDLGLNN---LNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF 647
+++ NN L+T P N SL+ L+ N I + +K+ +L L++ N F
Sbjct 204 LNMSHNNFFSLDTFPYKCLN---SLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDF 260
Query 648 DCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
CTCE + F+ WI + + E+ C TP G PV
Sbjct 261 ACTCEHQS-FLQWIKDQRQLLVEV-ERMECATPSDKQGMPV 299
Score = 58.9 bits (141), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 76/283 (27%), Positives = 125/283 (44%), Gaps = 51/283 (18%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
SS +LEL SN+++ G F + T + LSLS
Sbjct 28 SSATRLELESNKLQSLPHGVFDKL---------------------------TQLTKLSLS 60
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
++ LS + T+L LDLS+N + + + +F L QLE+ +++N++ +
Sbjct 61 SNGLSFKGCCSQSDFGTTSLKYLDLSFNGV-ITMSSNFLGLEQLEHLDFQHSNLKQMSEF 119
Query 317 SLH-GLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDI-PGIKSNM 374
S+ L N+ YL++ + T+ + + F L LE L M N ++
Sbjct 120 SVFLSLRNLIYLDISHTHTRVAFNGI---------FNGLSSLEVLKMAGNSFQENFLPDI 170
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
FT L NL +L LS L L+ F SL S L +LN++ N +++ + L L+
Sbjct 171 FTELRNLTFLDLSQ--CQLEQLSPTAFNSL--SSLQVLNMSHNNFFSLDTFPYKCLNSLQ 226
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
VLD LN I +T ++ + + S +L LT+N FA
Sbjct 227 VLDYSLNHI---MTSKKQE-----LQHFPSSLAFLNLTQNDFA 261
Score = 56.2 bits (134), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 58/204 (28%), Positives = 99/204 (49%), Gaps = 11/204 (5%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S C+ LT VP +P++ T L L N+L+ LP F + +QLT L + N
Sbjct 3 SRCSCSGTEIRCNSKGLTSVPTGIPSSATRLELESNKLQSLPHGVFDKLTQLTKLSLSSN 62
Query 86 TISKLEPELCQK----LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKN- 140
+S C + LK L+L N + +S F L L ++++++
Sbjct 63 GLSF--KGCCSQSDFGTTSLKYLDLSFNGVITMSSN-FLGLEQLEHLDFQHSNLKQMSEF 119
Query 141 NPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSL 199
+ F+ +NLI LD+SH G L +L+ L ++ N Q ++ DIF +L
Sbjct 120 SVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQ--ENFLPDIFTELRNL 177
Query 200 KKLELSSNQIKEFSPGCFHAIGRL 223
L+LS Q+++ SP F+++ L
Sbjct 178 TFLDLSQCQLEQLSPTAFNSLSSL 201
>2z66_B B Variable lymphocyte receptor B, Toll-like receptor 4
Length=306
Score = 67.8 bits (164), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 76/281 (27%), Positives = 125/281 (44%), Gaps = 18/281 (6%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG-QELTGQEWRGLENIFEIYLSYNKYLQ 470
L L NK+ + F L L L L N + + Q G ++ + LS+N +
Sbjct 33 LELESNKLQSLPHGVFDKLTQLTKLSLSSNGLSFKGCCSQSDFGTTSLKYLDLSFNGVIT 92
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
++ N F + L+ L + LK + S S F LRNL LD+S+ + + + GL
Sbjct 93 MSSN-FLGLEQLEHLDFQHSNLKQM-SEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLS 150
Query 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKI 590
LE+L + N+ + P F + L +L L+L +++ F L L++
Sbjct 151 SLEVLKMAGNSFQENFL------PDIFTE-LRNLTFLDLSQCQLEQLSPTAFNSLSSLQV 203
Query 591 IDLGLNN---LNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF 647
+++ NN L+T P N SL+ L+ N I + +K+ +L L++ N F
Sbjct 204 LNMSHNNFFSLDTFPYKCLN---SLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDF 260
Query 648 DCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
CTCE + F+ WI + + E+ C TP G PV
Sbjct 261 ACTCEHQS-FLQWIKDQRQLLVEV-ERMECATPSDKQGMPV 299
Score = 58.9 bits (141), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 76/283 (27%), Positives = 125/283 (44%), Gaps = 51/283 (18%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
SS +LEL SN+++ G F + T + LSLS
Sbjct 28 SSATRLELESNKLQSLPHGVFDKL---------------------------TQLTKLSLS 60
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
++ LS + T+L LDLS+N + + + +F L QLE+ +++N++ +
Sbjct 61 SNGLSFKGCCSQSDFGTTSLKYLDLSFNGV-ITMSSNFLGLEQLEHLDFQHSNLKQMSEF 119
Query 317 SLH-GLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDI-PGIKSNM 374
S+ L N+ YL++ + T+ + + F L LE L M N ++
Sbjct 120 SVFLSLRNLIYLDISHTHTRVAFNGI---------FNGLSSLEVLKMAGNSFQENFLPDI 170
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
FT L NL +L LS L L+ F SL S L +LN++ N +++ + L L+
Sbjct 171 FTELRNLTFLDLSQ--CQLEQLSPTAFNSL--SSLQVLNMSHNNFFSLDTFPYKCLNSLQ 226
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
VLD LN I +T ++ + + S +L LT+N FA
Sbjct 227 VLDYSLNHI---MTSKKQE-----LQHFPSSLAFLNLTQNDFA 261
Score = 56.2 bits (134), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 58/204 (28%), Positives = 99/204 (49%), Gaps = 11/204 (5%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S C+ LT VP +P++ T L L N+L+ LP F + +QLT L + N
Sbjct 3 SRCSCSGTEIRCNSKGLTSVPTGIPSSATRLELESNKLQSLPHGVFDKLTQLTKLSLSSN 62
Query 86 TISKLEPELCQK----LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKN- 140
+S C + LK L+L N + +S F L L ++++++
Sbjct 63 GLSF--KGCCSQSDFGTTSLKYLDLSFNGVITMSSN-FLGLEQLEHLDFQHSNLKQMSEF 119
Query 141 NPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSL 199
+ F+ +NLI LD+SH G L +L+ L ++ N Q ++ DIF +L
Sbjct 120 SVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQ--ENFLPDIFTELRNL 177
Query 200 KKLELSSNQIKEFSPGCFHAIGRL 223
L+LS Q+++ SP F+++ L
Sbjct 178 TFLDLSQCQLEQLSPTAFNSLSSL 201
>2z66_D D Variable lymphocyte receptor B, Toll-like receptor 4
Length=306
Score = 67.8 bits (164), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 76/281 (27%), Positives = 125/281 (44%), Gaps = 18/281 (6%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG-QELTGQEWRGLENIFEIYLSYNKYLQ 470
L L NK+ + F L L L L N + + Q G ++ + LS+N +
Sbjct 33 LELESNKLQSLPHGVFDKLTQLTKLSLSSNGLSFKGCCSQSDFGTTSLKYLDLSFNGVIT 92
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
++ N F + L+ L + LK + S S F LRNL LD+S+ + + + GL
Sbjct 93 MSSN-FLGLEQLEHLDFQHSNLKQM-SEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLS 150
Query 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKI 590
LE+L + N+ + P F + L +L L+L +++ F L L++
Sbjct 151 SLEVLKMAGNSFQENFL------PDIFTE-LRNLTFLDLSQCQLEQLSPTAFNSLSSLQV 203
Query 591 IDLGLNN---LNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF 647
+++ NN L+T P N SL+ L+ N I + +K+ +L L++ N F
Sbjct 204 LNMSHNNFFSLDTFPYKCLN---SLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDF 260
Query 648 DCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
CTCE + F+ WI + + E+ C TP G PV
Sbjct 261 ACTCEHQS-FLQWIKDQRQLLVEV-ERMECATPSDKQGMPV 299
Score = 58.9 bits (141), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 76/283 (27%), Positives = 125/283 (44%), Gaps = 51/283 (18%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
SS +LEL SN+++ G F + T + LSLS
Sbjct 28 SSATRLELESNKLQSLPHGVFDKL---------------------------TQLTKLSLS 60
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
++ LS + T+L LDLS+N + + + +F L QLE+ +++N++ +
Sbjct 61 SNGLSFKGCCSQSDFGTTSLKYLDLSFNGV-ITMSSNFLGLEQLEHLDFQHSNLKQMSEF 119
Query 317 SLH-GLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDI-PGIKSNM 374
S+ L N+ YL++ + T+ + + F L LE L M N ++
Sbjct 120 SVFLSLRNLIYLDISHTHTRVAFNGI---------FNGLSSLEVLKMAGNSFQENFLPDI 170
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
FT L NL +L LS L L+ F SL S L +LN++ N +++ + L L+
Sbjct 171 FTELRNLTFLDLSQ--CQLEQLSPTAFNSL--SSLQVLNMSHNNFFSLDTFPYKCLNSLQ 226
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
VLD LN I +T ++ + + S +L LT+N FA
Sbjct 227 VLDYSLNHI---MTSKKQE-----LQHFPSSLAFLNLTQNDFA 261
Score = 56.2 bits (134), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 58/204 (28%), Positives = 99/204 (49%), Gaps = 11/204 (5%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S C+ LT VP +P++ T L L N+L+ LP F + +QLT L + N
Sbjct 3 SRCSCSGTEIRCNSKGLTSVPTGIPSSATRLELESNKLQSLPHGVFDKLTQLTKLSLSSN 62
Query 86 TISKLEPELCQK----LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKN- 140
+S C + LK L+L N + +S F L L ++++++
Sbjct 63 GLSF--KGCCSQSDFGTTSLKYLDLSFNGVITMSSN-FLGLEQLEHLDFQHSNLKQMSEF 119
Query 141 NPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSL 199
+ F+ +NLI LD+SH G L +L+ L ++ N Q ++ DIF +L
Sbjct 120 SVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQ--ENFLPDIFTELRNL 177
Query 200 KKLELSSNQIKEFSPGCFHAIGRL 223
L+LS Q+++ SP F+++ L
Sbjct 178 TFLDLSQCQLEQLSPTAFNSLSSL 201
>2z66_C C Variable lymphocyte receptor B, Toll-like receptor 4
Length=306
Score = 67.8 bits (164), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 76/281 (27%), Positives = 125/281 (44%), Gaps = 18/281 (6%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG-QELTGQEWRGLENIFEIYLSYNKYLQ 470
L L NK+ + F L L L L N + + Q G ++ + LS+N +
Sbjct 33 LELESNKLQSLPHGVFDKLTQLTKLSLSSNGLSFKGCCSQSDFGTTSLKYLDLSFNGVIT 92
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
++ N F + L+ L + LK + S S F LRNL LD+S+ + + + GL
Sbjct 93 MSSN-FLGLEQLEHLDFQHSNLKQM-SEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLS 150
Query 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKI 590
LE+L + N+ + P F + L +L L+L +++ F L L++
Sbjct 151 SLEVLKMAGNSFQENFL------PDIFTE-LRNLTFLDLSQCQLEQLSPTAFNSLSSLQV 203
Query 591 IDLGLNN---LNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF 647
+++ NN L+T P N SL+ L+ N I + +K+ +L L++ N F
Sbjct 204 LNMSHNNFFSLDTFPYKCLN---SLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDF 260
Query 648 DCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPV 688
CTCE + F+ WI + + E+ C TP G PV
Sbjct 261 ACTCEHQS-FLQWIKDQRQLLVEV-ERMECATPSDKQGMPV 299
Score = 58.9 bits (141), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 76/283 (27%), Positives = 125/283 (44%), Gaps = 51/283 (18%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
SS +LEL SN+++ G F + T + LSLS
Sbjct 28 SSATRLELESNKLQSLPHGVFDKL---------------------------TQLTKLSLS 60
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
++ LS + T+L LDLS+N + + + +F L QLE+ +++N++ +
Sbjct 61 SNGLSFKGCCSQSDFGTTSLKYLDLSFNGV-ITMSSNFLGLEQLEHLDFQHSNLKQMSEF 119
Query 317 SLH-GLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDI-PGIKSNM 374
S+ L N+ YL++ + T+ + + F L LE L M N ++
Sbjct 120 SVFLSLRNLIYLDISHTHTRVAFNGI---------FNGLSSLEVLKMAGNSFQENFLPDI 170
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
FT L NL +L LS L L+ F SL S L +LN++ N +++ + L L+
Sbjct 171 FTELRNLTFLDLSQ--CQLEQLSPTAFNSL--SSLQVLNMSHNNFFSLDTFPYKCLNSLQ 226
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
VLD LN I +T ++ + + S +L LT+N FA
Sbjct 227 VLDYSLNHI---MTSKKQE-----LQHFPSSLAFLNLTQNDFA 261
Score = 56.2 bits (134), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 58/204 (28%), Positives = 99/204 (49%), Gaps = 11/204 (5%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S C+ LT VP +P++ T L L N+L+ LP F + +QLT L + N
Sbjct 3 SRCSCSGTEIRCNSKGLTSVPTGIPSSATRLELESNKLQSLPHGVFDKLTQLTKLSLSSN 62
Query 86 TISKLEPELCQK----LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKN- 140
+S C + LK L+L N + +S F L L ++++++
Sbjct 63 GLSF--KGCCSQSDFGTTSLKYLDLSFNGVITMSSN-FLGLEQLEHLDFQHSNLKQMSEF 119
Query 141 NPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSL 199
+ F+ +NLI LD+SH G L +L+ L ++ N Q ++ DIF +L
Sbjct 120 SVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQ--ENFLPDIFTELRNL 177
Query 200 KKLELSSNQIKEFSPGCFHAIGRL 223
L+LS Q+++ SP F+++ L
Sbjct 178 TFLDLSQCQLEQLSPTAFNSLSSL 201
>6bxd_A A Variable Lymphocyte Receptor 2
Length=209
Score = 65.9 bits (159), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 52/174 (30%), Positives = 79/174 (45%), Gaps = 13/174 (7%)
Query 501 PFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG 560
P Q + T +D S ++A++ + ++L L N + +L PG
Sbjct 20 PSQCSCSGTTVDCSGKSLASVPTGIPT---TTQVLGLSSNQITKL----EPG----VFDS 68
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L +L IL L N +P VF L LK + N L +LPA VF+ L L LQ N
Sbjct 69 LVNLQILVLYQNQLTTLPAGVFDRLINLKELYFSNNQLTSLPAGVFDKLTQLTRLELQTN 128
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSH 674
+ S+ + F ++LT + + NP+DC C I + NWI + H +I H
Sbjct 129 QLKSIPRGAFD-NLKSLTNIYLFNNPWDCECSDILYLKNWIVQ-HASIVNPDGH 180
Score = 57.8 bits (138), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 24/156 (15%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DCS L VP +PT VL L+ NQ
Sbjct 21 SQCSCSGTTVDCSGKSLASVPTGIPTTTQVLGLSSNQ----------------------- 57
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
I+KLEP + L L++L L N+L+ L F NL EL+ +N + + F K
Sbjct 58 -ITKLEPGVFDSLVNLQILVLYQNQLTTLPAGVFDRLINLKELYFSNNQLTSLPAGVFDK 116
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
L L+L N L S G L++L + L NN
Sbjct 117 LTQLTRLELQTNQLKSIPRGAFDNLKSLTNIYLFNN 152
Score = 47.0 bits (110), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 36/103 (35%), Positives = 53/103 (51%), Gaps = 2/103 (2%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L SN I K++ F NL L L N L++ G +L NL+EL SNN++ +L
Sbjct 51 LGLSSNQITKLEPGVFDSLVNLQILVLYQNQLTTLPAGVFDRLINLKELYFSNNQLTSLP 110
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+ D + L +LEL +NQ+K G F + L ++L N
Sbjct 111 AGVFDKL--TQLTRLELQTNQLKSIPRGAFDNLKSLTNIYLFN 151
Score = 40.0 bits (92), Expect = 0.059, Method: Compositional matrix adjust.
Identities = 34/107 (32%), Positives = 55/107 (51%), Gaps = 3/107 (3%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L L+ N+I+K+E F L +L++L L N++ L + L N+ E+Y S N+
Sbjct 49 QVLGLSSNQITKLEPGVFDSLVNLQILVLYQNQL-TTLPAGVFDRLINLKELYFSNNQLT 107
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
L F + L RL L+ LK++ F L++LT + L NN
Sbjct 108 SLPAGVFDKLTQLTRLELQTNQLKSIPR--GAFDNLKSLTNIYLFNN 152
Score = 34.7 bits (78), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 38/113 (34%), Positives = 56/113 (50%), Gaps = 6/113 (5%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
++ + L LSSNQI + PG F ++ L L L QL +L + L N ++ L S
Sbjct 46 TTTQVLGLSSNQITKLEPGVFDSLVNLQILVLYQNQLT-TLPAGVFDRLIN--LKELYFS 102
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
N+QL++ F K T LT L+L N L + +F L L +L +NN
Sbjct 103 NNQLTSLPAGVF--DKLTQLTRLELQTNQLKSIPRGAFDNLKSLTNIYL-FNN 152
Score = 33.5 bits (75), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 28/82 (34%), Positives = 40/82 (49%), Gaps = 2/82 (2%)
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
L LS N ++ + G L NLQ L+L N++ L + D N LK+L S+NQ+
Sbjct 51 LGLSSNQITKLEPGVFDSLVNLQILVLYQNQLTTLPAGVFDRLIN--LKELYFSNNQLTS 108
Query 212 FSPGCFHAIGRLFGLFLNNVQL 233
G F + +L L L QL
Sbjct 109 LPAGVFDKLTQLTRLELQTNQL 130
>6bxa_D D Variable Lymphocyte Receptor 2
Length=209
Score = 65.9 bits (159), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 52/174 (30%), Positives = 79/174 (45%), Gaps = 13/174 (7%)
Query 501 PFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG 560
P Q + T +D S ++A++ + ++L L N + +L PG
Sbjct 20 PSQCSCSGTTVDCSGKSLASVPTGIPT---TTQVLGLSSNQITKL----EPG----VFDS 68
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L +L IL L N +P VF L LK + N L +LPA VF+ L L LQ N
Sbjct 69 LVNLQILVLYQNQLTTLPAGVFDRLINLKELYFSNNQLTSLPAGVFDKLTQLTRLELQTN 128
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSH 674
+ S+ + F ++LT + + NP+DC C I + NWI + H +I H
Sbjct 129 QLKSIPRGAFD-NLKSLTNIYLFNNPWDCECSDILYLKNWIVQ-HASIVNPDGH 180
Score = 57.8 bits (138), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 24/156 (15%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DCS L VP +PT VL L+ NQ
Sbjct 21 SQCSCSGTTVDCSGKSLASVPTGIPTTTQVLGLSSNQ----------------------- 57
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
I+KLEP + L L++L L N+L+ L F NL EL+ +N + + F K
Sbjct 58 -ITKLEPGVFDSLVNLQILVLYQNQLTTLPAGVFDRLINLKELYFSNNQLTSLPAGVFDK 116
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
L L+L N L S G L++L + L NN
Sbjct 117 LTQLTRLELQTNQLKSIPRGAFDNLKSLTNIYLFNN 152
Score = 47.0 bits (110), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 36/103 (35%), Positives = 53/103 (51%), Gaps = 2/103 (2%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L SN I K++ F NL L L N L++ G +L NL+EL SNN++ +L
Sbjct 51 LGLSSNQITKLEPGVFDSLVNLQILVLYQNQLTTLPAGVFDRLINLKELYFSNNQLTSLP 110
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+ D + L +LEL +NQ+K G F + L ++L N
Sbjct 111 AGVFDKL--TQLTRLELQTNQLKSIPRGAFDNLKSLTNIYLFN 151
Score = 40.0 bits (92), Expect = 0.059, Method: Compositional matrix adjust.
Identities = 34/107 (32%), Positives = 55/107 (51%), Gaps = 3/107 (3%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L L+ N+I+K+E F L +L++L L N++ L + L N+ E+Y S N+
Sbjct 49 QVLGLSSNQITKLEPGVFDSLVNLQILVLYQNQL-TTLPAGVFDRLINLKELYFSNNQLT 107
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
L F + L RL L+ LK++ F L++LT + L NN
Sbjct 108 SLPAGVFDKLTQLTRLELQTNQLKSIPR--GAFDNLKSLTNIYLFNN 152
Score = 34.7 bits (78), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 38/113 (34%), Positives = 56/113 (50%), Gaps = 6/113 (5%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
++ + L LSSNQI + PG F ++ L L L QL +L + L N ++ L S
Sbjct 46 TTTQVLGLSSNQITKLEPGVFDSLVNLQILVLYQNQLT-TLPAGVFDRLIN--LKELYFS 102
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
N+QL++ F K T LT L+L N L + +F L L +L +NN
Sbjct 103 NNQLTSLPAGVF--DKLTQLTRLELQTNQLKSIPRGAFDNLKSLTNIYL-FNN 152
Score = 33.5 bits (75), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 28/82 (34%), Positives = 40/82 (49%), Gaps = 2/82 (2%)
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
L LS N ++ + G L NLQ L+L N++ L + D N LK+L S+NQ+
Sbjct 51 LGLSSNQITKLEPGVFDSLVNLQILVLYQNQLTTLPAGVFDRLIN--LKELYFSNNQLTS 108
Query 212 FSPGCFHAIGRLFGLFLNNVQL 233
G F + +L L L QL
Sbjct 109 LPAGVFDKLTQLTRLELQTNQL 130
>6bxa_C C Variable Lymphocyte Receptor 2
Length=209
Score = 65.9 bits (159), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 52/174 (30%), Positives = 79/174 (45%), Gaps = 13/174 (7%)
Query 501 PFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG 560
P Q + T +D S ++A++ + ++L L N + +L PG
Sbjct 20 PSQCSCSGTTVDCSGKSLASVPTGIPT---TTQVLGLSSNQITKL----EPG----VFDS 68
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L +L IL L N +P VF L LK + N L +LPA VF+ L L LQ N
Sbjct 69 LVNLQILVLYQNQLTTLPAGVFDRLINLKELYFSNNQLTSLPAGVFDKLTQLTRLELQTN 128
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSH 674
+ S+ + F ++LT + + NP+DC C I + NWI + H +I H
Sbjct 129 QLKSIPRGAFD-NLKSLTNIYLFNNPWDCECSDILYLKNWIVQ-HASIVNPDGH 180
Score = 57.8 bits (138), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 24/156 (15%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DCS L VP +PT VL L+ NQ
Sbjct 21 SQCSCSGTTVDCSGKSLASVPTGIPTTTQVLGLSSNQ----------------------- 57
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
I+KLEP + L L++L L N+L+ L F NL EL+ +N + + F K
Sbjct 58 -ITKLEPGVFDSLVNLQILVLYQNQLTTLPAGVFDRLINLKELYFSNNQLTSLPAGVFDK 116
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
L L+L N L S G L++L + L NN
Sbjct 117 LTQLTRLELQTNQLKSIPRGAFDNLKSLTNIYLFNN 152
Score = 47.0 bits (110), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 36/103 (35%), Positives = 53/103 (51%), Gaps = 2/103 (2%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L SN I K++ F NL L L N L++ G +L NL+EL SNN++ +L
Sbjct 51 LGLSSNQITKLEPGVFDSLVNLQILVLYQNQLTTLPAGVFDRLINLKELYFSNNQLTSLP 110
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+ D + L +LEL +NQ+K G F + L ++L N
Sbjct 111 AGVFDKL--TQLTRLELQTNQLKSIPRGAFDNLKSLTNIYLFN 151
Score = 40.0 bits (92), Expect = 0.059, Method: Compositional matrix adjust.
Identities = 34/107 (32%), Positives = 55/107 (51%), Gaps = 3/107 (3%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L L+ N+I+K+E F L +L++L L N++ L + L N+ E+Y S N+
Sbjct 49 QVLGLSSNQITKLEPGVFDSLVNLQILVLYQNQL-TTLPAGVFDRLINLKELYFSNNQLT 107
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
L F + L RL L+ LK++ F L++LT + L NN
Sbjct 108 SLPAGVFDKLTQLTRLELQTNQLKSIPR--GAFDNLKSLTNIYLFNN 152
Score = 34.7 bits (78), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 38/113 (34%), Positives = 56/113 (50%), Gaps = 6/113 (5%)
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
++ + L LSSNQI + PG F ++ L L L QL +L + L N ++ L S
Sbjct 46 TTTQVLGLSSNQITKLEPGVFDSLVNLQILVLYQNQLT-TLPAGVFDRLIN--LKELYFS 102
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
N+QL++ F K T LT L+L N L + +F L L +L +NN
Sbjct 103 NNQLTSLPAGVF--DKLTQLTRLELQTNQLKSIPRGAFDNLKSLTNIYL-FNN 152
Score = 33.5 bits (75), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 28/82 (34%), Positives = 40/82 (49%), Gaps = 2/82 (2%)
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
L LS N ++ + G L NLQ L+L N++ L + D N LK+L S+NQ+
Sbjct 51 LGLSSNQITKLEPGVFDSLVNLQILVLYQNQLTTLPAGVFDRLIN--LKELYFSNNQLTS 108
Query 212 FSPGCFHAIGRLFGLFLNNVQL 233
G F + +L L L QL
Sbjct 109 LPAGVFDKLTQLTRLELQTNQL 130
>4bv4_C R PROTEIN TOLL, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA
Length=446
Score = 68.6 bits (166), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 79/276 (29%), Positives = 131/276 (47%), Gaps = 20/276 (7%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLR----RLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
+LT +P +L T++ NL+H +LR +P+ F L S++ G N + ++ +
Sbjct 134 RLTHIPANLLTDMR--NLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFG 191
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
K+P LK LNL N+L L+ F T++ + + N I+++ ++ F N+ ++LS
Sbjct 192 KMPKLKQLNLWSNQLHNLTKHDFEGATSVLGIDIHDNGIEQLPHDVFAHLTNVTDINLSA 251
Query 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGC 216
N S G ++L E+ L NN++ L + +FAN EL QI
Sbjct 252 NLFRSLPQGLFDHNKHLNEVRLMNNRV-PLATLPSRLFANQP----EL---QILRLRAEL 303
Query 217 FHAIGRLF--GLFLNNVQLGPSLTEKLCLELANTSIR--NLSLSNSQLSTTSNTTFLGLK 272
G LF + N+ LG +L + L L + +L LSN++L+ ++ F
Sbjct 304 QSLPGDLFEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLDLSNNRLTHLPDSLF--AH 361
Query 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
TNLT L L+ N L V + F L L+ +L N
Sbjct 362 TTNLTDLRLASNQLKSVPDGIFDRLTSLQKIWLHTN 397
Score = 59.3 bits (142), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 68/296 (23%), Positives = 131/296 (44%), Gaps = 20/296 (7%)
Query 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
I +N+ T + NL +L L ++ + + F L + L + NK+ ++ F
Sbjct 138 IPANLLTDMRNLSHLELR---ANIEEMPSHLFDDLEN--LESIEFGSNKLRQMPRGIFGK 192
Query 430 LGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRR 489
+ L+ L+L N++ LT ++ G ++ I + N QL + FA + ++ + L
Sbjct 193 MPKLKQLNLWSNQL-HNLTKHDFEGATSVLGIDIHDNGIEQLPHDVFAHLTNVTDINLSA 251
Query 490 VALKNVDSSPSPFQPLRNLTILDLSNNNI--ANINDDMLEGLEKLEILDLQHNNLARLWK 547
+++ F ++L + L NN + A + + +L+IL L R
Sbjct 252 NLFRSLPQGL--FDHNKHLNEVRLMNNRVPLATLPSRLFANQPELQILRL------RAEL 303
Query 548 HANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
+ PG + + + ++L N +P + + L +DL N L LP S+F
Sbjct 304 QSLPGD---LFEHSTQITNISLGDNLLKTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFA 360
Query 608 NQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ +L L L N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 361 HTTNLTDLRLASNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 415
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 42/183 (23%), Positives = 80/183 (44%), Gaps = 13/183 (7%)
Query 441 NEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPS 500
+ +G +T Q L + + + + N + +L L LR N++ PS
Sbjct 108 DNLGMNITRQHLDRLHGLKRFRFTTRRLTHIPANLLTDMRNLSHLELR----ANIEEMPS 163
Query 501 P-FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLK 559
F L NL ++ +N + + + + KL+ L+L N L L KH +
Sbjct 164 HLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLKQLNLWSNQLHNLTKHD--------FE 215
Query 560 GLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQK 619
G + + +++ NG +++P +VF L + I+L N +LP +F++ L + L
Sbjct 216 GATSVLGIDIHDNGIEQLPHDVFAHLTNVTDINLSANLFRSLPQGLFDHNKHLNEVRLMN 275
Query 620 NLI 622
N +
Sbjct 276 NRV 278
>3m18_A A Variable lymphocyte receptor A diversity region
Length=251
Score = 66.6 bits (161), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 53/181 (29%), Positives = 82/181 (45%), Gaps = 2/181 (1%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C + DC L VP +P + L+L L L A F ++LT L++ +N +
Sbjct 12 CNEGKKEVDCQGKSLDSVPSGIPADTEKLDLQSTGLATLSDATFRGLTKLTWLNLDYNQL 71
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
L + L L L L +N+L+ L F T L +L+L N ++ + + F +
Sbjct 72 QTLSAGVFDDLTELGTLGLANNQLASLPLGVFDHLTQLDKLYLGGNQLKSLPSGVFDRLT 131
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
L L L+ N L S G +L NLQ L LS N++Q++ D L+ + L N
Sbjct 132 KLKELRLNTNQLQSIPAGAFDKLTNLQTLSLSTNQLQSVPHGAFDRLG--KLQTITLFGN 189
Query 208 Q 208
Q
Sbjct 190 Q 190
Score = 65.5 bits (158), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 59/212 (28%), Positives = 89/212 (42%), Gaps = 35/212 (17%)
Query 493 KNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPG 552
K++DS PS + LDL + +A ++D GL KL L+L +N L L
Sbjct 24 KSLDSVPSGIPA--DTEKLDLQSTGLATLSDATFRGLTKLTWLNLDYNQLQTL------- 74
Query 553 GPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
L+ L L L +N +P+ VF L +L + LG N L +LP+ VF+ L
Sbjct 75 -SAGVFDDLTELGTLGLANNQLASLPLGVFDHLTQLDKLYLGGNQLKSLPSGVFDRLTKL 133
Query 613 KSLNLQKNLITSVEKKVFGP--------------------AFRNLTELD---MRFNPFDC 649
K L L N + S+ F AF L +L + N FDC
Sbjct 134 KELRLNTNQLQSIPAGAFDKLTNLQTLSLSTNQLQSVPHGAFDRLGKLQTITLFGNQFDC 193
Query 650 T-CESIAWFVNWINETHTNIPELSSHYLCNTP 680
+ CE++ + WI E + + + L +P
Sbjct 194 SRCETL-YLSQWIRENSNKVKDGTGQNLHESP 224
Score = 46.2 bits (108), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 45/160 (28%), Positives = 73/160 (46%), Gaps = 13/160 (8%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
LDL L + + +F L +L + L+YN +Q L + L + L L +
Sbjct 40 LDLQSTGLATLSDATFRGLTKLTWLNLDYNQLQTLSAGVFDDLTELGTLGLANN------ 93
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
LASLP F L L+ L + N + + S +F L LK L L+ + L+++
Sbjct 94 QLASLPL---GVFDHLTQLDKLYLGGNQLKSLPSGVFDRLTKLKELRLNTN--QLQSIPA 148
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDL 438
F L + L L+L+ N++ + AF LG L+ + L
Sbjct 149 GAFDKLTN--LQTLSLSTNQLQSVPHGAFDRLGKLQTITL 186
Score = 44.3 bits (103), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 52/166 (31%), Positives = 73/166 (44%), Gaps = 31/166 (19%)
Query 104 LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTK 163
L+LQ L+ LSD TF T LT L+L N +Q + F L TL L++N L+S
Sbjct 40 LDLQSTGLATLSDATFRGLTKLTWLNLDYNQLQTLSAGVFDDLTELGTLGLANNQLASLP 99
Query 164 LGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGR 222
LG +F + + L KL L NQ+K G F + +
Sbjct 100 LG---------------------------VFDHLTQLDKLYLGGNQLKSLPSGVFDRLTK 132
Query 223 LFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
L L LN QL S+ +L N ++ LSLS +QL + + F
Sbjct 133 LKELRLNTNQL-QSIPAGAFDKLTN--LQTLSLSTNQLQSVPHGAF 175
Score = 38.9 bits (89), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 8/152 (5%)
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRT 395
QS LA+L D +F+ L L LN++ N + + + +F L L L L+N+ L +
Sbjct 43 QSTGLATLS---DATFRGLTKLTWLNLDYNQLQTLSAGVFDDLTELGTLGLANN--QLAS 97
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL 455
L F L L L L N++ + S F L L+ L L N++ Q + + L
Sbjct 98 LPLGVFDHLTQ--LDKLYLGGNQLKSLPSGVFDRLTKLKELRLNTNQL-QSIPAGAFDKL 154
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
N+ + LS N+ + +F + LQ + L
Sbjct 155 TNLQTLSLSTNQLQSVPHGAFDRLGKLQTITL 186
>4qbz_B B Toll-like receptor 8
Length=811
Score = 68.9 bits (167), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 179/754 (24%), Positives = 285/754 (38%), Gaps = 178/754 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+A+CS+ +L +VP T +T LD+ N I+ + E
Sbjct 24 IAECSNRRLQEVPQ------------------------TVGKYVTELDLSDNFITHITNE 59
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
Q L L +NL HN Q N I + F+ KNL L
Sbjct 60 SFQGLQNLTKINLNHNPNVQXXXXXXXXXXNGL----------NITDGAFLNLKNLRELL 109
Query 154 LSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN------ 207
L N L G E+L EL L N I + E + N LK L L+ N
Sbjct 110 LEDNQLPQIPSGLP---ESLTELSLIQNNIYNITKEGISRLIN--LKNLYLAWNCYFNKV 164
Query 208 -QIKEFSPGCFHAIGR---LFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
+ G F + L F + + P L +S+R L LSN+Q+
Sbjct 165 CEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP---------SSLRKLFLSNTQIKYI 215
Query 264 SNTTFLGLKWTNLTMLDLSYN------------------NLNVVGNDSFAW--LPQLEYF 303
S F GL NLT+LDLS N ++N+ D FA+ L QL Y
Sbjct 216 SEEDFKGL--INLTLLDLSGNCPRCFNAPFPCVPCDGGASINI---DRFAFQNLTQLRYL 270
Query 304 FLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS----LASLPKID--DFSFQWLKCL 357
L +++ + + + +++ L+L+ ++ I+ L LP+++ D SF ++K
Sbjct 271 NLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGS 330
Query 358 --EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILNL 414
+H+N+ N F+ L++L+ L L + L + F L P L +NL
Sbjct 331 YPQHINISRN---------FSKLLSLRALHLRGYV--FQELREDDFQPLMQLPNLSTINL 379
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQ----------------------EW 452
N I +I+ F +LE++ L N I + E+
Sbjct 380 GINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXXXXXXXXXXXXXXXXXXXXFEF 439
Query 453 RGLENIFEIY--------LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS------- 497
N + +Y K L L+ NS + Q L +A N+ +
Sbjct 440 DPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVL 499
Query 498 SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF 557
S + F + ++ LDL+NN + N L L LE+LDL +N + ++ A + F
Sbjct 500 SGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYN--SHYFRIAGVTHHLEF 557
Query 558 LKGLSHLHILNLESNGF-------------------------------DEIPVEVFKDLF 586
++ ++L +LNL N D + +FK L
Sbjct 558 IQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLK 617
Query 587 ELKIIDLGLNNLNTLPASVF-NNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L +DL LN L +P F N SL L++ N++ + F L LD+R N
Sbjct 618 NLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQ-QFPRLELLDLRGN 676
Query 646 PFDCTCESIAWFVNWINE---THTNIPELSSHYL 676
+S++ F + + +H I L S +L
Sbjct 677 KLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFL 710
Score = 67.4 bits (163), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 95/340 (28%), Positives = 152/340 (45%), Gaps = 28/340 (8%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L++ N I I N F L ++ L+LS + ++ + L+ F ++ H + L+LT N++
Sbjct 464 LDLSLNSIFFIGPNQFENLPDIACLNLSAN-SNAQVLSGTEFSAIPH--VKYLDLTNNRL 520
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTG-----QEWRGLENIFEIYLSYNKYLQLTRN 474
+ A + L LEVLDL N + G + + N+ + LS+N LT
Sbjct 521 DFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDK 580
Query 475 SFALVPSLQRLML---RRVALKNVDSSP--SPFQPLRNLTILDLSNNNIANI-NDDMLEG 528
SL L+ R L N D + S F+ L+NLT LDLS N + +I N+ L
Sbjct 581 YNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNL 640
Query 529 LEKLEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFE 587
L L + N L W L+ L +L+L N + +
Sbjct 641 PASLTELHINDNMLKFFNWT---------LLQQFPRLELLDLRGNKLLFLTDSLSDFTSS 691
Query 588 LKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNP 646
L+ + L N ++ LP+ + SLK L+L NL+ ++ K L+ L++ NP
Sbjct 692 LRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNP 751
Query 647 FDCTCESIAWFVNWINE-THTNIPELSSHYLCNTPPHYHG 685
F+CTC+ I F W++E + IP L +C +P G
Sbjct 752 FECTCD-IGDFRRWMDEHLNVKIPRLVD-VICASPGDQRG 789
Score = 43.1 bits (100), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 43/157 (27%), Positives = 72/157 (46%), Gaps = 25/157 (16%)
Query 52 NITVLNLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
N+T L+L+ N+L+ +P F + LT L + N + L Q+ P L++L+L+ N+
Sbjct 618 NLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNK 677
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L+D F ++L TL LSHN +S G ++
Sbjct 678 LLFLTDSLSDFTSSLR------------------------TLLLSHNRISHLPSGFLSEV 713
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+L+ L LS+N ++ + L+ + L LEL N
Sbjct 714 SSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 750
Score = 43.1 bits (100), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 75/268 (28%), Positives = 112/268 (42%), Gaps = 63/268 (24%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT----ISKLEP--ELCQKLPMLKVLNL 106
+ L+LT+N+L A+ T S L LD+ +N+ I+ + E Q LKVLNL
Sbjct 510 VKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNL 569
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP-------FVKQKNLITLDLSHNGL 159
HN + L+DK +L EL N + + N+ F KNL LDLS N L
Sbjct 570 SHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRL 629
Query 160 SSTKLGTQVQL-ENLQELLLSNNKI---------QALKSEELDIFAN------------- 196
+ L +L EL +++N + Q + E LD+ N
Sbjct 630 KHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFT 689
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
SSL+ L LS N+I G FL+ V +S+++L LS
Sbjct 690 SSLRTLLLSHNRISHLPSG-----------FLSEV----------------SSLKHLDLS 722
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
++ L T + + T L+ML+L N
Sbjct 723 SNLLKTINKSALETKTTTKLSMLELHGN 750
Score = 38.5 bits (88), Expect = 0.37, Method: Compositional matrix adjust.
Identities = 136/581 (23%), Positives = 214/581 (37%), Gaps = 131/581 (23%)
Query 44 QVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN------------------ 85
VP LP+++ L L++ Q++ + +F LT LD+ N
Sbjct 193 HVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGA 252
Query 86 -----------------------TISKLEPELCQKLPMLKVLNLQHN------------- 109
++ K+ + +P LKVL+L+ N
Sbjct 253 SINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLT 312
Query 110 -----ELSQLS--------------DKTFAFCTNLTELHLMSNSIQKIKNN---PFVKQK 147
E+ LS + F+ +L LHL Q+++ + P ++
Sbjct 313 MLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLP 372
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
NL T++L N + NL+ + LS N+I L
Sbjct 373 NLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXXXXXXXXXXXXXXXX 432
Query 208 QIK--EFSPGC--FH-----------AIGRLFGLFLNNV-QLGPSLTEKLCLELANTSIR 251
EF P +H A G+ L LN++ +GP+ E L + +
Sbjct 433 XXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFEN----LPDIACL 488
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
NLS +NS S T F + ++ LDL+ N L+ + L LE L YN
Sbjct 489 NLS-ANSNAQVLSGTEFSAIP--HVKYLDLTNNRLDFDNASALTELSDLEVLDLSYN--S 543
Query 312 HLF-----SHSL---HGLFNVRYLNLKRS--------FTKQSISLASLPKIDDFSFQWLK 355
H F +H L N++ LNL + + +S SL L FS L
Sbjct 544 HYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELV----FSGNRLD 599
Query 356 CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLT 415
L N +DN I F GL NL L L S L+ + NE F++L S L L++
Sbjct 600 IL--WNDDDNRYISI----FKGLKNLTRLDL--SLNRLKHIPNEAFLNLPAS-LTELHIN 650
Query 416 KNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNS 475
N + LE+LDL N++ LT ++ + LS+N+ L
Sbjct 651 DNMLKFFNWTLLQQFPRLELLDLRGNKL-LFLTDSLSDFTSSLRTLLLSHNRISHLPSGF 709
Query 476 FALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
+ V SL+ L L LK ++ S + L++L+L N
Sbjct 710 LSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 750
>6zjz_A A Toll-like receptor 8
Length=801
Score = 68.9 bits (167), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 189/807 (23%), Positives = 297/807 (37%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNXXXXXX 79
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 80 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 136
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 137 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 195
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 196 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 243
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 244 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 301
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 302 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 356
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 357 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 414
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 415 XXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 470
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 471 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 522
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 523 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 582
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDL 585
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 583 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 640
Query 586 FELKIID---------------------------------------------LGLNNLNT 600
EL I D L N ++
Sbjct 641 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 700
Query 601 LPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVN 659
LP+ SLK L+L NL+ ++ L+ L++ NPF+CTC+ I F
Sbjct 701 LPSGFXXXVSSLKHLDLSSNLLKTINXXXXXXXXTTKLSMLELHGNPFECTCD-IGDFRR 759
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 760 WMDEHLNVKIPRLVD-VICASPGDQRG 785
>5awc_D D Toll-like receptor 8
Length=811
Score = 68.6 bits (166), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 189/806 (23%), Positives = 296/806 (37%), Gaps = 196/806 (24%)
Query 35 ADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS------ 88
A+CS+ +L +VP + +T L+L+ N + + LT +++ N
Sbjct 25 AECSNRRLQEVPQTVGKYVTELDLSDNFITHITNEXXXXXQNLTKINLNHNPNVXXXXXX 84
Query 89 --------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKN 140
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 85 XXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNITK 141
Query 141 NPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN---------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 142 EGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPS 200
Query 173 -LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 201 SLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP-----C 248
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NVV 289
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 249 DGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEIA 306
Query 290 GNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 307 SGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL----- 360
Query 344 PKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL---------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 -REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXXX 419
Query 387 -----------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIE 423
SN + R L + + L+L+ N I I
Sbjct 420 XXXXXXXXXXXXXXXXXXEFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFIG 475
Query 424 SDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPS 481
+ F L + L+L N Q L+G E+ + ++ KYL LT N F +
Sbjct 476 PNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASA 527
Query 482 LQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLE 530
L L V + V Q NL +L+LS+NNI + D LE
Sbjct 528 LTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKS 587
Query 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLF 586
+E++ N L LW + + I KGL +L L+L N IP E F L
Sbjct 588 LVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLT 645
Query 587 ELKIID---------------------------------------------LGLNNLNTL 601
EL I D L N ++ L
Sbjct 646 ELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHL 705
Query 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN-LTELDMRFNPFDCTCESIAWFVNW 660
P+ + SLK L+L NL+ ++ K L+ L++ NPF+CTC+ I F W
Sbjct 706 PSGFLSEVSSLKHLDLSSNLLKTINKSXXXXXXXTKLSMLELHGNPFECTCD-IGDFRRW 764
Query 661 INE-THTNIPELSSHYLCNTPPHYHG 685
++E + IP L +C +P G
Sbjct 765 MDEHLNVKIPRLVD-VICASPGDQRG 789
>4r09_B B Toll-like receptor 8
Length=811
Score = 68.6 bits (166), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 179/754 (24%), Positives = 284/754 (38%), Gaps = 178/754 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+A+CS+ +L +VP T +T LD+ N I+ + E
Sbjct 24 IAECSNRRLQEVPQ------------------------TVGKYVTELDLSDNFITHITNE 59
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
Q L L +NL HN Q N I + F+ KNL L
Sbjct 60 SFQGLQNLTKINLNHNPNVQXXXXXXXXXXNGL----------NITDGAFLNLKNLRELL 109
Query 154 LSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN------ 207
L N L G E+L EL L N I + E + N LK L L+ N
Sbjct 110 LEDNQLPQIPSGLP---ESLTELSLIQNNIYNITKEGISRLIN--LKNLYLAWNCYFNKV 164
Query 208 -QIKEFSPGCFHAIGR---LFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
+ G F + L F + + P L +S+R L LSN+Q+
Sbjct 165 CEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP---------SSLRKLFLSNTQIKYI 215
Query 264 SNTTFLGLKWTNLTMLDLSYN------------------NLNVVGNDSFAW--LPQLEYF 303
S F GL NLT+LDLS N ++N+ D FA+ L QL Y
Sbjct 216 SEEDFKGL--INLTLLDLSGNCPRCFNAPFPCVPCDGGASINI---DRFAFQNLTQLRYL 270
Query 304 FLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS----LASLPKID--DFSFQWLKC- 356
L +++ + + + +++ L+L+ ++ I+ L LP+++ D SF ++K
Sbjct 271 NLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGS 330
Query 357 -LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILNL 414
+H+N+ N F+ L++L+ L L + L + F L P L +NL
Sbjct 331 YPQHINISRN---------FSKLLSLRALHLRGYV--FQELREDDFQPLMQLPNLSTINL 379
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQ----------------------EW 452
N I +I+ F +LE++ L N I E+
Sbjct 380 GINFIKQIDFKLFQNFSNLEIIYLSENRISPXXXXXXXXXXXXXXXXXXXXXXXXXDFEF 439
Query 453 RGLENIFEIY--------LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS------- 497
N + +Y K L L+ NS + Q L +A N+ +
Sbjct 440 DPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVL 499
Query 498 SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF 557
S + F + ++ LDL+NN + N L L LE+LDL +N + ++ A + F
Sbjct 500 SGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYN--SHYFRIAGVTHHLEF 557
Query 558 LKGLSHLHILNLESNGF-------------------------------DEIPVEVFKDLF 586
++ ++L +LNL N D + +FK L
Sbjct 558 IQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLK 617
Query 587 ELKIIDLGLNNLNTLPASVF-NNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L +DL LN L +P F N SL L++ N++ + F L LD+R N
Sbjct 618 NLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQ-QFPRLELLDLRGN 676
Query 646 PFDCTCESIAWFVNWINE---THTNIPELSSHYL 676
+S++ F + + +H I L S +L
Sbjct 677 KLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFL 710
Score = 67.4 bits (163), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 95/340 (28%), Positives = 152/340 (45%), Gaps = 28/340 (8%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L++ N I I N F L ++ L+LS + ++ + L+ F ++ H + L+LT N++
Sbjct 464 LDLSLNSIFFIGPNQFENLPDIACLNLSAN-SNAQVLSGTEFSAIPH--VKYLDLTNNRL 520
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTG-----QEWRGLENIFEIYLSYNKYLQLTRN 474
+ A + L LEVLDL N + G + + N+ + LS+N LT
Sbjct 521 DFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDK 580
Query 475 SFALVPSLQRLML---RRVALKNVDSSP--SPFQPLRNLTILDLSNNNIANI-NDDMLEG 528
SL L+ R L N D + S F+ L+NLT LDLS N + +I N+ L
Sbjct 581 YNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNL 640
Query 529 LEKLEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFE 587
L L + N L W L+ L +L+L N + +
Sbjct 641 PASLTELHINDNMLKFFNWT---------LLQQFPRLELLDLRGNKLLFLTDSLSDFTSS 691
Query 588 LKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNP 646
L+ + L N ++ LP+ + SLK L+L NL+ ++ K L+ L++ NP
Sbjct 692 LRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNP 751
Query 647 FDCTCESIAWFVNWINE-THTNIPELSSHYLCNTPPHYHG 685
F+CTC+ I F W++E + IP L +C +P G
Sbjct 752 FECTCD-IGDFRRWMDEHLNVKIPRLVD-VICASPGDQRG 789
Score = 43.1 bits (100), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 43/157 (27%), Positives = 72/157 (46%), Gaps = 25/157 (16%)
Query 52 NITVLNLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
N+T L+L+ N+L+ +P F + LT L + N + L Q+ P L++L+L+ N+
Sbjct 618 NLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNK 677
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L+D F ++L TL LSHN +S G ++
Sbjct 678 LLFLTDSLSDFTSSLR------------------------TLLLSHNRISHLPSGFLSEV 713
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+L+ L LS+N ++ + L+ + L LEL N
Sbjct 714 SSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 750
Score = 43.1 bits (100), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 75/268 (28%), Positives = 112/268 (42%), Gaps = 63/268 (24%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT----ISKLEP--ELCQKLPMLKVLNL 106
+ L+LT+N+L A+ T S L LD+ +N+ I+ + E Q LKVLNL
Sbjct 510 VKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNL 569
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP-------FVKQKNLITLDLSHNGL 159
HN + L+DK +L EL N + + N+ F KNL LDLS N L
Sbjct 570 SHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRL 629
Query 160 SSTKLGTQVQL-ENLQELLLSNNKI---------QALKSEELDIFAN------------- 196
+ L +L EL +++N + Q + E LD+ N
Sbjct 630 KHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFT 689
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
SSL+ L LS N+I G FL+ V +S+++L LS
Sbjct 690 SSLRTLLLSHNRISHLPSG-----------FLSEV----------------SSLKHLDLS 722
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
++ L T + + T L+ML+L N
Sbjct 723 SNLLKTINKSALETKTTTKLSMLELHGN 750
Score = 38.1 bits (87), Expect = 0.46, Method: Compositional matrix adjust.
Identities = 70/270 (26%), Positives = 112/270 (41%), Gaps = 18/270 (7%)
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLMSNSIQK 137
+LD+ N+I + P + LP + LNL N +Q LS F+ ++ L L +N +
Sbjct 463 ALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDF 522
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE------NLQELLLSNNKIQALKSEEL 191
+ + +L LDLS+N G LE NL+ L LS+N I L +
Sbjct 523 DNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKY- 581
Query 192 DIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIR 251
+ SL +L S N++ + +F N +L SL + N +
Sbjct 582 -NLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNR--LKHIPNEAFL 638
Query 252 NLSLSNSQLSTTSNTTFLGLKWT------NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFL 305
NL S ++L N WT L +LDL N L + + + L L
Sbjct 639 NLPASLTELHINDNMLKF-FNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLL 697
Query 306 EYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
+N I HL S L + ++++L+L + K
Sbjct 698 SHNRISHLPSGFLSEVSSLKHLDLSSNLLK 727
Score = 37.4 bits (85), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 52/168 (31%), Positives = 74/168 (44%), Gaps = 10/168 (6%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTS-------LDVGFNTISKLEPELCQKLPMLKV 103
TN+ VLNL+HN + L L LD+ +N + + L L
Sbjct 562 TNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTR 621
Query 104 LNLQHNELSQLSDKTFA-FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSST 162
L+L N L + ++ F +LTELH+ N ++ + L LDL N L
Sbjct 622 LDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFL 681
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+L+ LLLS+N+I L S L SSLK L+LSSN +K
Sbjct 682 TDSLSDFTSSLRTLLLSHNRISHLPSGFLSEV--SSLKHLDLSSNLLK 727
>2j67_B B TOLL LIKE RECEPTOR 10
Length=178
Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 44/143 (31%), Positives = 71/143 (50%), Gaps = 2/143 (1%)
Query 756 YAAYIIHAYKDKDWVW-EHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKII 814
+ A+I ++ D WV E ++EKED S+ CL E F+ G E IV+ I++S K I
Sbjct 36 FHAFISYSEHDSLWVKNELIPNLEKEDGSILICLYESYFDPGKSISENIVSFIEKSYKSI 95
Query 815 FVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKSH 874
FV++ + +++ C ++ + A +N D IIL+ LE IP Y +
Sbjct 96 FVLSPNFVQNEWC-HYEFYFAHHNLFHENSDHIILILLEPIPFYXXXXXXXXXXXXXEKK 154
Query 875 CILNWPVQKERIGAFRHKLQVAL 897
L WP + + G F L+ A+
Sbjct 155 AYLEWPKDRRKCGLFWANLRAAI 177
>7r53_A A Toll-like receptor 8
Length=807
Score = 68.2 bits (165), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 95/340 (28%), Positives = 152/340 (45%), Gaps = 28/340 (8%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L++ N I I N F L ++ L+LS + ++ + L+ F ++ H + L+LT N++
Sbjct 460 LDLSLNSIFFIGPNQFENLPDIACLNLSAN-SNAQVLSGTEFSAIPH--VKYLDLTNNRL 516
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTG-----QEWRGLENIFEIYLSYNKYLQLTRN 474
+ A + L LEVLDL N + G + + N+ + LS+N LT
Sbjct 517 DFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTXX 576
Query 475 SFALVPSLQRLML---RRVALKNVDSSP--SPFQPLRNLTILDLSNNNIANI-NDDMLEG 528
SL L+ R L N D + S F+ L+NLT LDLS N + +I N+ L
Sbjct 577 XXLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNL 636
Query 529 LEKLEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFE 587
L L + N L W L+ L +L+L N + +
Sbjct 637 PASLTELHINDNMLKFFNWT---------LLQQFPRLELLDLRGNKLLFLTDSLSDFTSS 687
Query 588 LKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNP 646
L+ + L N ++ LP+ + SLK L+L NL+ ++ K L+ L++ NP
Sbjct 688 LRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNP 747
Query 647 FDCTCESIAWFVNWINE-THTNIPELSSHYLCNTPPHYHG 685
F+CTC+ I F W++E + IP L +C +P G
Sbjct 748 FECTCD-IGDFRRWMDEHLNVKIPRLVD-VICASPGDQRG 785
Score = 65.9 bits (159), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 170/747 (23%), Positives = 286/747 (38%), Gaps = 164/747 (22%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N P
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHN------PN 73
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
+ N ++D F NL EL L N + +I P ++L L
Sbjct 74 VXXXXXXXXXXXXGLN----ITDGAFLNLKNLRELLLEDNQLPQI---PSGLPESLTELS 126
Query 154 LSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
L N + + +L NL+ L L+ N E+ +I
Sbjct 127 LIQNNIYNITKEGISRLINLKNLYLAWNXXXXXXXEKTNI-------------------E 167
Query 214 PGCFHAIGR---LFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLG 270
G F + L F + + P L +S+R L LSN+Q+ S F G
Sbjct 168 DGVFETLTNLELLSLSFNSLSHVPPKLP---------SSLRKLFLSNTQIKYISEEDFKG 218
Query 271 LKWTNLTMLDLSYN------------------NLNVVGNDSFAW--LPQLEYFFLEYNNI 310
L NLT+LDLS N ++N+ D FA+ L QL Y L ++
Sbjct 219 L--INLTLLDLSGNCPRCFNAPFPCVPCDGGASINI---DRFAFQNLTQLRYLNLSSTSL 273
Query 311 QHLFSHSLHGLFNVRYLNLKRSFTKQSIS----LASLPKID--DFSFQWLKC--LEHLNM 362
+ + + + +++ L+L+ ++ I+ L LP+++ D SF ++K +H+N+
Sbjct 274 RKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINI 333
Query 363 EDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILNLTKNKISK 421
N F+ L++L+ L L + L + F L P L +NL N I +
Sbjct 334 SRN---------FSKLLSLRALHLRGYV--FQELREDDFQPLMQLPNLSTINLGINFIKQ 382
Query 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL----------------------ENIF 459
I+ F +LE++ L N I N +
Sbjct 383 IDFKLFQNFSNLEIIYLSENRISPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXDPHSNFY 442
Query 460 EIY--------LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS-------SPSPFQP 504
+Y K L L+ NS + Q L +A N+ + S + F
Sbjct 443 HFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSA 502
Query 505 LRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
+ ++ LDL+NN + N L L LE+LDL +N + ++ A + F++ ++L
Sbjct 503 IPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYN--SHYFRIAGVTHHLEFIQNFTNL 560
Query 565 HILNLESNGF-------------------------------DEIPVEVFKDLFELKIIDL 593
+LNL N D + +FK L L +DL
Sbjct 561 KVLNLSHNNIYTLTXXXXLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDL 620
Query 594 GLNNLNTLPASVF-NNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCE 652
LN L +P F N SL L++ N++ + F L LD+R N +
Sbjct 621 SLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQ-QFPRLELLDLRGNKLLFLTD 679
Query 653 SIAWFVNWINE---THTNIPELSSHYL 676
S++ F + + +H I L S +L
Sbjct 680 SLSDFTSSLRTLLLSHNRISHLPSGFL 706
Score = 43.1 bits (100), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 43/157 (27%), Positives = 72/157 (46%), Gaps = 25/157 (16%)
Query 52 NITVLNLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
N+T L+L+ N+L+ +P F + LT L + N + L Q+ P L++L+L+ N+
Sbjct 614 NLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNK 673
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L+D F ++L TL LSHN +S G ++
Sbjct 674 LLFLTDSLSDFTSSLR------------------------TLLLSHNRISHLPSGFLSEV 709
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+L+ L LS+N ++ + L+ + L LEL N
Sbjct 710 SSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 746
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 52/168 (31%), Positives = 74/168 (44%), Gaps = 10/168 (6%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTS-------LDVGFNTISKLEPELCQKLPMLKV 103
TN+ VLNL+HN + L L LD+ +N + + L L
Sbjct 558 TNLKVLNLSHNNIYTLTXXXXLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTR 617
Query 104 LNLQHNELSQLSDKTFA-FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSST 162
L+L N L + ++ F +LTELH+ N ++ + L LDL N L
Sbjct 618 LDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFL 677
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+L+ LLLS+N+I L S L SSLK L+LSSN +K
Sbjct 678 TDSLSDFTSSLRTLLLSHNRISHLPSGFLSEV--SSLKHLDLSSNLLK 723
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 73/268 (27%), Positives = 110/268 (41%), Gaps = 63/268 (24%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT----ISKLEP--ELCQKLPMLKVLNL 106
+ L+LT+N+L A+ T S L LD+ +N+ I+ + E Q LKVLNL
Sbjct 506 VKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNL 565
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP-------FVKQKNLITLDLSHNGL 159
HN + L+ +L EL N + + N+ F KNL LDLS N L
Sbjct 566 SHNNIYTLTXXXXLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRL 625
Query 160 SSTKLGTQVQL-ENLQELLLSNNKI---------QALKSEELDIFAN------------- 196
+ L +L EL +++N + Q + E LD+ N
Sbjct 626 KHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFT 685
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
SSL+ L LS N+I G FL+ V +S+++L LS
Sbjct 686 SSLRTLLLSHNRISHLPSG-----------FLSEV----------------SSLKHLDLS 718
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
++ L T + + T L+ML+L N
Sbjct 719 SNLLKTINKSALETKTTTKLSMLELHGN 746
Score = 38.9 bits (89), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 70/270 (26%), Positives = 111/270 (41%), Gaps = 18/270 (7%)
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLMSNSIQK 137
+LD+ N+I + P + LP + LNL N +Q LS F+ ++ L L +N +
Sbjct 459 ALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDF 518
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE------NLQELLLSNNKIQALKSEEL 191
+ + +L LDLS+N G LE NL+ L LS+N I L
Sbjct 519 DNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTXXX- 577
Query 192 DIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIR 251
+ SL +L S N++ + +F N +L SL + N +
Sbjct 578 -XLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNR--LKHIPNEAFL 634
Query 252 NLSLSNSQLSTTSNTTFLGLKWT------NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFL 305
NL S ++L N WT L +LDL N L + + + L L
Sbjct 635 NLPASLTELHINDNMLKF-FNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLL 693
Query 306 EYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
+N I HL S L + ++++L+L + K
Sbjct 694 SHNRISHLPSGFLSEVSSLKHLDLSSNLLK 723
>6ka7_A A repebody
Length=256
Score = 65.5 bits (158), Expect = 3e-10, Method: Compositional matrix adjust.
Identities = 63/213 (30%), Positives = 97/213 (46%), Gaps = 16/213 (8%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L L L ++ S + L NLT L+L N + + + + + L L+ L L
Sbjct 56 LPNVRYLALGGNKLHDI----SALKELTNLTYLELKWNQLQILPNGVFDKLTNLKELVLN 111
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P L++L LNL N +P VF L L ++L N L
Sbjct 112 SNQLQSL--------PDGVFDKLTNLTYLNLAHNQLQSLPDGVFDKLTNLTGLELCGNQL 163
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
+LP VF+ LK L L +N + SV VF +L + + NP+DCT I +
Sbjct 164 QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTXXXIRYLS 222
Query 659 NWINETHTNIPELSSHYLC--NTPPHYHGFPVR 689
WIN+ H+ + S+ + + G PVR
Sbjct 223 EWINK-HSGVVRNSAGSVAPDSAKCSGSGKPVR 254
Score = 64.7 bits (156), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 49/131 (37%), Positives = 63/131 (48%), Gaps = 0/131 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T L L NQL+ LP F + + L L + N + L + KL L LNL HN+
Sbjct 79 TNLTYLELKWNQLQILPNGVFDKLTNLKELVLNSNQLQSLPDGVFDKLTNLTYLNLAHNQ 138
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L D F TNLT L L N +Q + F K L L L N L S G +L
Sbjct 139 LQSLPDGVFDKLTNLTGLELCGNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFDRL 198
Query 171 ENLQELLLSNN 181
+LQ + L +N
Sbjct 199 TSLQYIWLHDN 209
Score = 58.2 bits (139), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 52/164 (32%), Positives = 80/164 (49%), Gaps = 3/164 (2%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L++ +N +
Sbjct 36 SIDQIIANNSDIKSVQGIQYLP-NVRYLALGGNKLHDISA--LKELTNLTYLELKWNQLQ 92
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
L + KL LK L L N+L L D F TNLT L+L N +Q + + F K N
Sbjct 93 ILPNGVFDKLTNLKELVLNSNQLQSLPDGVFDKLTNLTYLNLAHNQLQSLPDGVFDKLTN 152
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
L L+L N L S G +L L++L L N+++++ D
Sbjct 153 LTGLELCGNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFD 196
Score = 53.9 bits (128), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/96 (38%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Query 41 KLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
+L +PD D TN+T LNL HNQL+ LP F + + LT L++ N + L + K
Sbjct 114 QLQSLPDGVFDKLTNLTYLNLAHNQLQSLPDGVFDKLTNLTGLELCGNQLQSLPEGVFDK 173
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
L LK L L N+L + D F T+L + L N
Sbjct 174 LTQLKDLRLYQNQLKSVPDGVFDRLTSLQYIWLHDN 209
Score = 38.9 bits (89), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 47/140 (34%), Positives = 66/140 (47%), Gaps = 7/140 (5%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L L N++Q L + D N LK+L L+SNQ++ G F + L L L
Sbjct 77 ELTNLTYLELKWNQLQILPNGVFDKLTN--LKELVLNSNQLQSLPDGVFDKLTNLTYLNL 134
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
+ QL SL + + +L N + L L +QL + F K T L L L N L
Sbjct 135 AHNQL-QSLPDGVFDKLTN--LTGLELCGNQLQSLPEGVF--DKLTQLKDLRLYQNQLKS 189
Query 289 VGNDSFAWLPQLEYFFLEYN 308
V + F L L+Y +L N
Sbjct 190 VPDGVFDRLTSLQYIWLHDN 209
>4arr_B B TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA
Length=279
Score = 65.5 bits (158), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 36/110 (33%), Positives = 57/110 (52%), Gaps = 2/110 (2%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L + +L L L +N +E+P +F DL L+ I+ G N L +P +F LK
Sbjct 139 PANLLTDMRNLSHLELRAN-IEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLK 197
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
LNL N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 198 QLNLASNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 246
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 31/97 (32%), Positives = 53/97 (55%), Gaps = 6/97 (6%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLR----RLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
+LT +P +L T++ NL+H +LR +P+ F L S++ G N + ++ +
Sbjct 134 RLTHIPANLLTDMR--NLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFG 191
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
K+P LK LNL N+L + D F T+L ++ L +N
Sbjct 192 KMPKLKQLNLASNQLKSVPDGIFDRLTSLQKIWLHTN 228
>4arn_D D TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA
Length=279
Score = 65.5 bits (158), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 36/110 (33%), Positives = 57/110 (52%), Gaps = 2/110 (2%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L + +L L L +N +E+P +F DL L+ I+ G N L +P +F LK
Sbjct 139 PANLLTDMRNLSHLELRAN-IEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLK 197
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
LNL N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 198 QLNLASNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 246
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 31/97 (32%), Positives = 53/97 (55%), Gaps = 6/97 (6%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLR----RLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
+LT +P +L T++ NL+H +LR +P+ F L S++ G N + ++ +
Sbjct 134 RLTHIPANLLTDMR--NLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFG 191
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
K+P LK LNL N+L + D F T+L ++ L +N
Sbjct 192 KMPKLKQLNLASNQLKSVPDGIFDRLTSLQKIWLHTN 228
>4arr_A A TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA
Length=279
Score = 65.5 bits (158), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 36/110 (33%), Positives = 57/110 (52%), Gaps = 2/110 (2%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L + +L L L +N +E+P +F DL L+ I+ G N L +P +F LK
Sbjct 139 PANLLTDMRNLSHLELRAN-IEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLK 197
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
LNL N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 198 QLNLASNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 246
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 31/97 (32%), Positives = 53/97 (55%), Gaps = 6/97 (6%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLR----RLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
+LT +P +L T++ NL+H +LR +P+ F L S++ G N + ++ +
Sbjct 134 RLTHIPANLLTDMR--NLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFG 191
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
K+P LK LNL N+L + D F T+L ++ L +N
Sbjct 192 KMPKLKQLNLASNQLKSVPDGIFDRLTSLQKIWLHTN 228
>4arn_B B TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA
Length=279
Score = 65.5 bits (158), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 36/110 (33%), Positives = 57/110 (52%), Gaps = 2/110 (2%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L + +L L L +N +E+P +F DL L+ I+ G N L +P +F LK
Sbjct 139 PANLLTDMRNLSHLELRAN-IEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLK 197
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
LNL N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 198 QLNLASNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 246
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 31/97 (32%), Positives = 53/97 (55%), Gaps = 6/97 (6%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLR----RLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
+LT +P +L T++ NL+H +LR +P+ F L S++ G N + ++ +
Sbjct 134 RLTHIPANLLTDMR--NLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFG 191
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
K+P LK LNL N+L + D F T+L ++ L +N
Sbjct 192 KMPKLKQLNLASNQLKSVPDGIFDRLTSLQKIWLHTN 228
>4arn_C C TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA
Length=279
Score = 65.5 bits (158), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 36/110 (33%), Positives = 57/110 (52%), Gaps = 2/110 (2%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L + +L L L +N +E+P +F DL L+ I+ G N L +P +F LK
Sbjct 139 PANLLTDMRNLSHLELRAN-IEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLK 197
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
LNL N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 198 QLNLASNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 246
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 31/97 (32%), Positives = 53/97 (55%), Gaps = 6/97 (6%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLR----RLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
+LT +P +L T++ NL+H +LR +P+ F L S++ G N + ++ +
Sbjct 134 RLTHIPANLLTDMR--NLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFG 191
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
K+P LK LNL N+L + D F T+L ++ L +N
Sbjct 192 KMPKLKQLNLASNQLKSVPDGIFDRLTSLQKIWLHTN 228
>4c2b_D D PLATELET GLYCOPROTEIN IB ALPHA CHAIN
Length=291
Score = 65.5 bits (158), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 76/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C +LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRRLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSL 184
Score = 59.3 bits (142), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 48/161 (30%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L N L LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 60/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N + ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 43.9 bits (102), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 43/145 (30%), Positives = 70/145 (48%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NN + +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNRLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 41.2 bits (95), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>4arn_A A TOLL RECEPTOR, VARIABLE LYMPHOCYTE RECEPTOR B.61 CHIMERA
Length=279
Score = 65.5 bits (158), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 36/110 (33%), Positives = 57/110 (52%), Gaps = 2/110 (2%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L + +L L L +N +E+P +F DL L+ I+ G N L +P +F LK
Sbjct 139 PANLLTDMRNLSHLELRAN-IEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFGKMPKLK 197
Query 614 SLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
LNL N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 198 QLNLASNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 246
Score = 44.3 bits (103), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 31/97 (32%), Positives = 53/97 (55%), Gaps = 6/97 (6%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLR----RLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
+LT +P +L T++ NL+H +LR +P+ F L S++ G N + ++ +
Sbjct 134 RLTHIPANLLTDMR--NLSHLELRANIEEMPSHLFDDLENLESIEFGSNKLRQMPRGIFG 191
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
K+P LK LNL N+L + D F T+L ++ L +N
Sbjct 192 KMPKLKQLNLASNQLKSVPDGIFDRLTSLQKIWLHTN 228
>6ty5_B B Toll-like receptor 8
Length=807
Score = 67.8 bits (164), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 95/340 (28%), Positives = 152/340 (45%), Gaps = 28/340 (8%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L++ N I I N F L ++ L+LS + ++ + L+ F ++ H + L+LT N++
Sbjct 460 LDLSLNSIFFIGPNQFENLPDIACLNLSAN-SNAQVLSGTEFSAIPH--VKYLDLTNNRL 516
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTG-----QEWRGLENIFEIYLSYNKYLQLTRN 474
+ A + L LEVLDL N + G + + N+ + LS+N LT
Sbjct 517 DFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTXK 576
Query 475 SFALVPSLQRLML---RRVALKNVDSSP--SPFQPLRNLTILDLSNNNIANI-NDDMLEG 528
SL L+ R L N D + S F+ L+NLT LDLS N + +I N+ L
Sbjct 577 YNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNL 636
Query 529 LEKLEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFE 587
L L + N L W L+ L +L+L N + +
Sbjct 637 PASLTELHINDNMLKFFNWT---------LLQQFPRLELLDLRGNKLLFLTDSLSDFTSS 687
Query 588 LKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNP 646
L+ + L N ++ LP+ + SLK L+L NL+ ++ K L+ L++ NP
Sbjct 688 LRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNP 747
Query 647 FDCTCESIAWFVNWINE-THTNIPELSSHYLCNTPPHYHG 685
F+CTC+ I F W++E + IP L +C +P G
Sbjct 748 FECTCD-IGDFRRWMDEHLNVKIPRLVD-VICASPGDQRG 785
Score = 65.5 bits (158), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 170/747 (23%), Positives = 286/747 (38%), Gaps = 164/747 (22%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N P
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHN------PN 73
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
N ++D F NL EL L N + +I P ++L L
Sbjct 74 XXXXXXXXXXXXXGLN----ITDGAFLNLKNLRELLLEDNQLPQI---PSGLPESLTELS 126
Query 154 LSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
L N + + +L NL+ L L+ N E+ +I
Sbjct 127 LIQNNIYNITKEGISRLINLKNLYLAWNCYXXXXCEKTNI-------------------E 167
Query 214 PGCFHAIGR---LFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLG 270
G F + L F + + P L +S+R L LSN+Q+ S F G
Sbjct 168 DGVFETLTNLELLSLSFNSLSHVPPKLP---------SSLRKLFLSNTQIKYISEEDFKG 218
Query 271 LKWTNLTMLDLSYN------------------NLNVVGNDSFAW--LPQLEYFFLEYNNI 310
L NLT+LDLS N ++N+ D FA+ L QL Y L ++
Sbjct 219 L--INLTLLDLSGNCPRCFNAPFPCVPCDGGASINI---DRFAFQNLTQLRYLNLSSTSL 273
Query 311 QHLFSHSLHGLFNVRYLNLKRSFTKQSIS----LASLPKID--DFSFQWLKCL--EHLNM 362
+ + + + +++ L+L+ ++ I+ L LP+++ D SF ++K +H+N+
Sbjct 274 RKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINI 333
Query 363 EDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILNLTKNKISK 421
N F+ L++L+ L L + L + F L P L +NL N I +
Sbjct 334 SRN---------FSKLLSLRALHLRGYV--FQELREDDFQPLMQLPNLSTINLGINFIKQ 382
Query 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL----------------------ENIF 459
I+ F +LE++ L N I + N +
Sbjct 383 IDFKLFQNFSNLEIIYLSENRISPLVXXXXXXXXXXXXXXXXXXXXXXXXXXXDPHSNFY 442
Query 460 EIY--------LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS-------SPSPFQP 504
+Y K L L+ NS + Q L +A N+ + S + F
Sbjct 443 HFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSA 502
Query 505 LRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
+ ++ LDL+NN + N L L LE+LDL +N + ++ A + F++ ++L
Sbjct 503 IPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYN--SHYFRIAGVTHHLEFIQNFTNL 560
Query 565 HILNLESNGF-------------------------------DEIPVEVFKDLFELKIIDL 593
+LNL N D + +FK L L +DL
Sbjct 561 KVLNLSHNNIYTLTXKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDL 620
Query 594 GLNNLNTLPASVF-NNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCE 652
LN L +P F N SL L++ N++ + F L LD+R N +
Sbjct 621 SLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQ-QFPRLELLDLRGNKLLFLTD 679
Query 653 SIAWFVNWINE---THTNIPELSSHYL 676
S++ F + + +H I L S +L
Sbjct 680 SLSDFTSSLRTLLLSHNRISHLPSGFL 706
Score = 43.1 bits (100), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 43/157 (27%), Positives = 72/157 (46%), Gaps = 25/157 (16%)
Query 52 NITVLNLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
N+T L+L+ N+L+ +P F + LT L + N + L Q+ P L++L+L+ N+
Sbjct 614 NLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNK 673
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L+D F ++L TL LSHN +S G ++
Sbjct 674 LLFLTDSLSDFTSSLR------------------------TLLLSHNRISHLPSGFLSEV 709
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+L+ L LS+N ++ + L+ + L LEL N
Sbjct 710 SSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 746
Score = 40.0 bits (92), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 74/268 (28%), Positives = 111/268 (41%), Gaps = 63/268 (24%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT----ISKLEP--ELCQKLPMLKVLNL 106
+ L+LT+N+L A+ T S L LD+ +N+ I+ + E Q LKVLNL
Sbjct 506 VKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNL 565
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP-------FVKQKNLITLDLSHNGL 159
HN + L+ K +L EL N + + N+ F KNL LDLS N L
Sbjct 566 SHNNIYTLTXKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRL 625
Query 160 SSTKLGTQVQL-ENLQELLLSNNKI---------QALKSEELDIFAN------------- 196
+ L +L EL +++N + Q + E LD+ N
Sbjct 626 KHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFT 685
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
SSL+ L LS N+I G FL+ V +S+++L LS
Sbjct 686 SSLRTLLLSHNRISHLPSG-----------FLSEV----------------SSLKHLDLS 718
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
++ L T + + T L+ML+L N
Sbjct 719 SNLLKTINKSALETKTTTKLSMLELHGN 746
Score = 38.1 bits (87), Expect = 0.46, Method: Compositional matrix adjust.
Identities = 70/270 (26%), Positives = 112/270 (41%), Gaps = 18/270 (7%)
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLMSNSIQK 137
+LD+ N+I + P + LP + LNL N +Q LS F+ ++ L L +N +
Sbjct 459 ALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDF 518
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE------NLQELLLSNNKIQALKSEEL 191
+ + +L LDLS+N G LE NL+ L LS+N I L +
Sbjct 519 DNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTXKY- 577
Query 192 DIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIR 251
+ SL +L S N++ + +F N +L SL + N +
Sbjct 578 -NLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNR--LKHIPNEAFL 634
Query 252 NLSLSNSQLSTTSNTTFLGLKWT------NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFL 305
NL S ++L N WT L +LDL N L + + + L L
Sbjct 635 NLPASLTELHINDNMLKF-FNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLL 693
Query 306 EYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
+N I HL S L + ++++L+L + K
Sbjct 694 SHNRISHLPSGFLSEVSSLKHLDLSSNLLK 723
Score = 37.7 bits (86), Expect = 0.64, Method: Compositional matrix adjust.
Identities = 52/168 (31%), Positives = 74/168 (44%), Gaps = 10/168 (6%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTS-------LDVGFNTISKLEPELCQKLPMLKV 103
TN+ VLNL+HN + L L LD+ +N + + L L
Sbjct 558 TNLKVLNLSHNNIYTLTXKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTR 617
Query 104 LNLQHNELSQLSDKTFA-FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSST 162
L+L N L + ++ F +LTELH+ N ++ + L LDL N L
Sbjct 618 LDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFL 677
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+L+ LLLS+N+I L S L SSLK L+LSSN +K
Sbjct 678 TDSLSDFTSSLRTLLLSHNRISHLPSGFLSEV--SSLKHLDLSSNLLK 723
>4om7_B B Toll-like receptor 6
Length=179
Score = 63.2 bits (152), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 40/144 (28%), Positives = 75/144 (52%), Gaps = 4/144 (3%)
Query 755 EYAAYIIHAYKDKDWVW-EHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
++ A+I ++ D WV E +EKED ++ CL ER+F G +E I+N I++S K
Sbjct 2 QFHAFISYSEHDSAWVKSELVPYLEKED--IQICLHERNFVPGKSIVENIINCIEKSYKS 59
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
IFV++ + ++ C ++++ A + +++IL+ LE IP + + + +
Sbjct 60 IFVLSPNFVQSEWC-HYELYFAHHNLFHEGSNNLILILLEPIPQNSIPNKYHKLKALMTQ 118
Query 874 HCILNWPVQKERIGAFRHKLQVAL 897
L WP +K + G F ++ A
Sbjct 119 RTYLQWPKEKSKRGLFWANIRAAF 142
>4om7_A A Toll-like receptor 6
Length=179
Score = 63.2 bits (152), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 40/144 (28%), Positives = 75/144 (52%), Gaps = 4/144 (3%)
Query 755 EYAAYIIHAYKDKDWVW-EHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
++ A+I ++ D WV E +EKED ++ CL ER+F G +E I+N I++S K
Sbjct 2 QFHAFISYSEHDSAWVKSELVPYLEKED--IQICLHERNFVPGKSIVENIINCIEKSYKS 59
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
IFV++ + ++ C ++++ A + +++IL+ LE IP + + + +
Sbjct 60 IFVLSPNFVQSEWC-HYELYFAHHNLFHEGSNNLILILLEPIPQNSIPNKYHKLKALMTQ 118
Query 874 HCILNWPVQKERIGAFRHKLQVAL 897
L WP +K + G F ++ A
Sbjct 119 RTYLQWPKEKSKRGLFWANIRAAF 142
>1p8t_A A Reticulon 4 receptor
Length=285
Score = 65.5 bits (158), Expect = 5e-10, Method: Composition-based stats.
Identities = 56/159 (35%), Positives = 80/159 (50%), Gaps = 13/159 (8%)
Query 483 QRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
QR+ L + +V ++ F+ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 34 QRIFLHGNRISHVPAAS--FRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDN-- 89
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLP 602
A+L + +P GL LH L+L+ G E+ +F+ L L+ + L N L LP
Sbjct 90 AQL-RSVDPAT----FHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALP 144
Query 603 ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
F + +L L L N I+SV ++ AFR L LD
Sbjct 145 DDTFRDLGNLTHLFLHGNRISSVPER----AFRGLHSLD 179
Score = 63.9 bits (154), Expect = 1e-09, Method: Composition-based stats.
Identities = 58/203 (29%), Positives = 89/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + L N++ +PAA+F LT L + N +++++
Sbjct 17 CPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFT 76
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF L LHL +Q++ F L L L
Sbjct 77 GLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQ 136
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ E SL +L L N++ P
Sbjct 137 DNALQALPDDTFRDLGNLTHLFLHGNRISSVP--ERAFRGLHSLDRLLLHQNRVAHVHPH 194
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ P+
Sbjct 195 AFRDLGRLMTLYLFANNLSALPT 217
Score = 60.5 bits (145), Expect = 2e-08, Method: Composition-based stats.
Identities = 55/188 (29%), Positives = 86/188 (46%), Gaps = 10/188 (5%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L IL L N +++I++ AF+ L LE LDL N + + + GL + ++L
Sbjct 57 LTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGL 116
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+L F + +LQ L L+ AL+ + F+ L NLT L L N I+++ + G
Sbjct 117 QELGPGLFRGLAALQYLYLQDNALQALPD--DTFRDLGNLTHLFLHGNRISSVPERAFRG 174
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L L+ L L N +A + HA + L L L L +N +P E L L
Sbjct 175 LHSLDRLLLHQNRVAHVHPHA--------FRDLGRLMTLYLFANNLSALPTEALAPLRAL 226
Query 589 KIIDLGLN 596
+ + L N
Sbjct 227 QYLRLNDN 234
Score = 47.8 bits (112), Expect = 3e-04, Method: Composition-based stats.
Identities = 54/204 (26%), Positives = 91/204 (45%), Gaps = 13/204 (6%)
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
N ++ V SF L +L N + + + + GL + L+L + A L
Sbjct 41 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDN--------AQL 92
Query 344 PKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS 403
+D +F L L L+++ + + +F GL L+YL L ++ +L+ L ++TF
Sbjct 93 RSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDN--ALQALPDDTFRD 150
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYL 463
L + L L L N+IS + AF L L+ L L N + + +R L + +YL
Sbjct 151 LGN--LTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAH-VHPHAFRDLGRLMTLYL 207
Query 464 SYNKYLQLTRNSFALVPSLQRLML 487
N L + A + +LQ L L
Sbjct 208 FANNLSALPTEALAPLRALQYLRL 231
Score = 47.0 bits (110), Expect = 5e-04, Method: Composition-based stats.
Identities = 60/225 (27%), Positives = 91/225 (40%), Gaps = 32/225 (14%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN + +I F L LDLS N
Sbjct 38 LHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNA------- 90
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLF 224
L+S + F L L L ++E PG F + L
Sbjct 91 -------------------QLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQ 131
Query 225 GLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+L + L +L + +L N + +L L +++S+ F GL +L L L N
Sbjct 132 YLYLQDNAL-QALPDDTFRDLGN--LTHLFLHGNRISSVPERAFRGLH--SLDRLLLHQN 186
Query 285 NLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
+ V +F L +L +L NN+ L + +L L ++YL L
Sbjct 187 RVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRL 231
>1ozn_A A Reticulon 4 receptor
Length=285
Score = 65.5 bits (158), Expect = 5e-10, Method: Composition-based stats.
Identities = 56/159 (35%), Positives = 80/159 (50%), Gaps = 13/159 (8%)
Query 483 QRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
QR+ L + +V ++ F+ RNLTIL L +N +A I+ GL LE LDL N
Sbjct 35 QRIFLHGNRISHVPAAS--FRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDN-- 90
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLP 602
A+L + +P GL LH L+L+ G E+ +F+ L L+ + L N L LP
Sbjct 91 AQL-RSVDPAT----FHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDNALQALP 145
Query 603 ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
F + +L L L N I+SV ++ AFR L LD
Sbjct 146 DDTFRDLGNLTHLFLHGNRISSVPER----AFRGLHSLD 180
Score = 63.9 bits (154), Expect = 1e-09, Method: Composition-based stats.
Identities = 58/203 (29%), Positives = 89/203 (44%), Gaps = 5/203 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L VP +P + L N++ +PAA+F LT L + N +++++
Sbjct 18 CPQQGLQAVPVGIPAASQRIFLHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFT 77
Query 97 KLPMLKVLNLQHN-ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
L +L+ L+L N +L + TF L LHL +Q++ F L L L
Sbjct 78 GLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQ 137
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L + T L NL L L N+I ++ E SL +L L N++ P
Sbjct 138 DNALQALPDDTFRDLGNLTHLFLHGNRISSVP--ERAFRGLHSLDRLLLHQNRVAHVHPH 195
Query 216 CFHAIGRLFGLFL--NNVQLGPS 236
F +GRL L+L NN+ P+
Sbjct 196 AFRDLGRLMTLYLFANNLSALPT 218
Score = 60.5 bits (145), Expect = 2e-08, Method: Composition-based stats.
Identities = 55/188 (29%), Positives = 86/188 (46%), Gaps = 10/188 (5%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L IL L N +++I++ AF+ L LE LDL N + + + GL + ++L
Sbjct 58 LTILWLHSNVLARIDAAAFTGLALLEQLDLSDNAQLRSVDPATFHGLGRLHTLHLDRCGL 117
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+L F + +LQ L L+ AL+ + F+ L NLT L L N I+++ + G
Sbjct 118 QELGPGLFRGLAALQYLYLQDNALQALPD--DTFRDLGNLTHLFLHGNRISSVPERAFRG 175
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L L+ L L N +A + HA + L L L L +N +P E L L
Sbjct 176 LHSLDRLLLHQNRVAHVHPHA--------FRDLGRLMTLYLFANNLSALPTEALAPLRAL 227
Query 589 KIIDLGLN 596
+ + L N
Sbjct 228 QYLRLNDN 235
Score = 47.8 bits (112), Expect = 3e-04, Method: Composition-based stats.
Identities = 54/204 (26%), Positives = 91/204 (45%), Gaps = 13/204 (6%)
Query 284 NNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASL 343
N ++ V SF L +L N + + + + GL + L+L + A L
Sbjct 42 NRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDN--------AQL 93
Query 344 PKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS 403
+D +F L L L+++ + + +F GL L+YL L ++ +L+ L ++TF
Sbjct 94 RSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQYLYLQDN--ALQALPDDTFRD 151
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYL 463
L + L L L N+IS + AF L L+ L L N + + +R L + +YL
Sbjct 152 LGN--LTHLFLHGNRISSVPERAFRGLHSLDRLLLHQNRVAH-VHPHAFRDLGRLMTLYL 208
Query 464 SYNKYLQLTRNSFALVPSLQRLML 487
N L + A + +LQ L L
Sbjct 209 FANNLSALPTEALAPLRALQYLRL 232
Score = 47.0 bits (110), Expect = 5e-04, Method: Composition-based stats.
Identities = 60/225 (27%), Positives = 91/225 (40%), Gaps = 32/225 (14%)
Query 106 LQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLG 165
L N +S + +F C NLT L L SN + +I F L LDLS N
Sbjct 39 LHGNRISHVPAASFRACRNLTILWLHSNVLARIDAAAFTGLALLEQLDLSDNA------- 91
Query 166 TQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLF 224
L+S + F L L L ++E PG F + L
Sbjct 92 -------------------QLRSVDPATFHGLGRLHTLHLDRCGLQELGPGLFRGLAALQ 132
Query 225 GLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+L + L +L + +L N + +L L +++S+ F GL +L L L N
Sbjct 133 YLYLQDNAL-QALPDDTFRDLGN--LTHLFLHGNRISSVPERAFRGLH--SLDRLLLHQN 187
Query 285 NLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
+ V +F L +L +L NN+ L + +L L ++YL L
Sbjct 188 RVAHVHPHAFRDLGRLMTLYLFANNLSALPTEALAPLRALQYLRL 232
>6kya_B B Toll-like receptor 8
Length=811
Score = 67.4 bits (163), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 190/807 (24%), Positives = 303/807 (38%), Gaps = 196/807 (24%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXNGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL--------------- 386
+ DDF L L +N+ N I I +F NL+ + L
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVXXXXXX 418
Query 387 ------------------------SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI 422
SN + R L + + L+L+ N I I
Sbjct 419 XXXXXXXXXXXXXXXXXXXXFDPHSNFYHFTRPLIKPQCAAYGKA----LDLSLNSIFFI 474
Query 423 ESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVP 480
+ F L + L+L N Q L+G E+ + ++ KYL LT N F
Sbjct 475 GPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNAS 526
Query 481 SLQRLMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGL 529
+L L V + V Q NL +L+LS+NNI + D LE
Sbjct 527 ALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESK 586
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDL---- 585
+E++ N L LW + + I KGL +L L+L N IP E F +L
Sbjct 587 SLVELV-FSGNRLDILW-NDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASL 644
Query 586 ---------------------FELKIIDLGLNNLNTLPASVFN------------NQVS- 611
L+++DL N L L S+ + N++S
Sbjct 645 TELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISH 704
Query 612 -----------LKSLNLQKNLITSVEK-KVFGPAFRNLTELDMRFNPFDCTCESIAWFVN 659
LK L+L NL+ ++ K L+ L++ NPF+CTC+ I F
Sbjct 705 LXXXXXXXXXSLKHLDLSSNLLKTINKXXXXXXXXXXLSMLELHGNPFECTCD-IGDFRR 763
Query 660 WINE-THTNIPELSSHYLCNTPPHYHG 685
W++E + IP L +C +P G
Sbjct 764 WMDEHLNVKIPRLVD-VICASPGDQRG 789
>4c2b_F F PLATELET GLYCOPROTEIN IB ALPHA CHAIN
Length=291
Score = 65.5 bits (158), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 76/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C +LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRRLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSL 184
Score = 58.9 bits (141), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 48/161 (30%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L N L LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 60/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N + ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 43.5 bits (101), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 43/145 (30%), Positives = 70/145 (48%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NN + +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNRLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 40.8 bits (94), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>4c2b_B B PLATELET GLYCOPROTEIN IB ALPHA CHAIN
Length=291
Score = 65.5 bits (158), Expect = 5e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 76/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C +LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRRLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSL 184
Score = 58.9 bits (141), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 48/161 (30%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L N L LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 60/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N + ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 43.5 bits (101), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 43/145 (30%), Positives = 70/145 (48%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NN + +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNRLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 40.8 bits (94), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>3p72_A A Platelet glycoprotein Ib alpha chain
Length=269
Score = 64.7 bits (156), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 76/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C +LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRQLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSL 184
Score = 59.3 bits (142), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 48/161 (30%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L N L LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 60/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N + ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 43.5 bits (101), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 43/145 (30%), Positives = 70/145 (48%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NN + +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNQLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 41.6 bits (96), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 52/111 (47%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N+L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>4c2b_H H PLATELET GLYCOPROTEIN IB ALPHA CHAIN
Length=291
Score = 65.1 bits (157), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 76/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C +LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRRLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSL 184
Score = 58.9 bits (141), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 48/161 (30%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L N L LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 44.7 bits (104), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 60/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N + ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 43.5 bits (101), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 43/145 (30%), Positives = 70/145 (48%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NN + +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNRLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 40.8 bits (94), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>4cnc_B B TROPHOBLAST GLYCOPROTEIN
Length=299
Score = 65.1 bits (157), Expect = 6e-10, Method: Composition-based stats.
Identities = 60/211 (28%), Positives = 98/211 (46%), Gaps = 11/211 (5%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTR---YSQLTSLDVG 83
+C+ + C + LT+VP DLP + L LT NQL LPA F R ++L +L++
Sbjct 11 ECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELAALNLS 70
Query 84 FNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
+ + ++ + LP L+ L+L HN L+ LS FAF + + S ++ I N+
Sbjct 71 GSRLDEVRAGAFEHLPSLRQLDLSHNPLADLS--PFAFSGSNASVSAPSPLVELILNH-- 126
Query 144 VKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKL 202
+ S G+ L L+ L+ L L++N L D+ A SL+ L
Sbjct 127 IVPPXXXXXXXSFEGMVVAALLAGRALQGLRRLELASNHFLYLPR---DVLAQLPSLRHL 183
Query 203 ELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
+LS+N + + F + L L L + L
Sbjct 184 DLSNNSLVSLTYVSFRNLTHLESLHLEDNAL 214
Score = 49.3 bits (116), Expect = 1e-04, Method: Composition-based stats.
Identities = 63/239 (26%), Positives = 91/239 (38%), Gaps = 55/239 (23%)
Query 464 SYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIND 523
+Y + L LT N A++P+ RR PL L L+LS + + +
Sbjct 35 AYVRNLFLTGNQLAVLPA--GAFARR-------------PPLAELAALNLSGSRLDEVRA 79
Query 524 DMLEGLEKLEILDLQHNNLARLWKHANPGG--------PIYFL----------------- 558
E L L LDL HN LA L A G P+ L
Sbjct 80 GAFEHLPSLRQLDLSHNPLADLSPFAFSGSNASVSAPSPLVELILNHIVPPXXXXXXXSF 139
Query 559 -----------KGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
+ L L L L SN F +P +V L L+ +DL N+L +L F
Sbjct 140 EGMVVAALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFR 199
Query 608 NQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRF--NPFDCTCESIAWFVNWINET 664
N L+SL+L+ N + + + L + + NP+ C C +A V W+ ET
Sbjct 200 NLTHLESLHLEDNALKVLHNGTLA-ELQGLPHIRVFLDNNPWVCDCH-MADMVTWLKET 256
Score = 35.0 bits (79), Expect = 3.5, Method: Composition-based stats.
Identities = 21/73 (29%), Positives = 38/73 (52%), Gaps = 0/73 (0%)
Query 77 LTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ 136
L L++ N L ++ +LP L+ L+L +N L L+ +F T+L LHL N+++
Sbjct 156 LRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHLESLHLEDNALK 215
Query 137 KIKNNPFVKQKNL 149
+ N + + L
Sbjct 216 VLHNGTLAELQGL 228
>4c2a_B B PLATELET GLYCOPROTEIN IB ALPHA CHAIN
Length=291
Score = 65.1 bits (157), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 76/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C +LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRRLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSL 184
Score = 58.9 bits (141), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 48/161 (30%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L N L LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 60/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N + ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 43.5 bits (101), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 43/145 (30%), Positives = 70/145 (48%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NN + +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNRLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 40.8 bits (94), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNRLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>7ylg_A A Toll-like receptor 2
Length=176
Score = 62.8 bits (151), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 40/146 (27%), Positives = 69/146 (47%), Gaps = 2/146 (1%)
Query 756 YAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKIIF 815
+ A+I ++ D DW EH + D K C ERDF+ G L I I+ S K++F
Sbjct 15 FDAFISYSEHDADWTKEHLLKKLETD-GFKICYHERDFKPGHPVLGNIFYCIENSHKVLF 73
Query 816 VITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKSHC 875
V++ + C +++++ A + DS+I+V LE++P + R + K
Sbjct 74 VLSPSFVNSCWC-QYELYFAEHRVXXXXQDSLIMVVLEDLPPDSVPQKFSKLRKLLKRKT 132
Query 876 ILNWPVQKERIGAFRHKLQVALGSKN 901
L W ++ + F H+L L + N
Sbjct 133 YLKWSPEEHKQKIFWHQLAAVLKTTN 158
>1u0n_D D Platelet glycoprotein Ib
Length=265
Score = 64.7 bits (156), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 76/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C +LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRQLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSL 184
Score = 59.3 bits (142), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 48/161 (30%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L N L LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 60/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N + ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 43.9 bits (102), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 43/145 (30%), Positives = 70/145 (48%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NN + +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNQLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 41.6 bits (96), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 52/111 (47%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N+L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>5uff_A A RBC36
Length=216
Score = 63.5 bits (153), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 50/158 (32%), Positives = 72/158 (46%), Gaps = 31/158 (20%)
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
+IL L N + +L PG L +L L L SN +PV VF L +L ++D
Sbjct 31 QILYLHDNQITKL----EPG----VFDSLINLKELYLGSNQLGALPVGVFDSLTQLTVLD 82
Query 593 LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE-------------------KKVFGPA 633
LG N L LP++VF+ V LK L + N +T + K + A
Sbjct 83 LGTNQLTVLPSAVFDRLVHLKELFMCCNKLTELPRGIERLTHLTHLALDQNQLKSIPHGA 142
Query 634 FRNLTELDMRF---NPFDCTCESIAWFVNWINETHTNI 668
F L+ L + NP+DC C I + NW+ + HT+I
Sbjct 143 FDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD-HTSI 179
Score = 53.9 bits (128), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 67/156 (43%), Gaps = 1/156 (1%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DC + VP +PTN +L L NQ+ +L F L L +G N
Sbjct 3 SQCSCSGTTVDCRSKRHASVPAGIPTNAQILYLHDNQITKLEPGVFDSLINLKELYLGSN 62
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ L + L L VL+L N+L+ L F +L EL + N + ++ +
Sbjct 63 QLGALPVGVFDSLTQLTVLDLGTNQLTVLPSAVFDRLVHLKELFMCCNKLTELPRG-IER 121
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
+L L L N L S G +L +L L N
Sbjct 122 LTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGN 157
Score = 37.0 bits (84), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 38/121 (31%), Positives = 60/121 (50%), Gaps = 14/121 (12%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I ++ +F LINLK L L ++ L L F SL L +L+L N++
Sbjct 33 LYLHDNQITKLEPGVFDSLINLKELYLGSN--QLGALPVGVFDSLTQ--LTVLDLGTNQL 88
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALV 479
+ + S F L HL+ L + N++ EL RG+E L++ +L L +N +
Sbjct 89 TVLPSAVFDRLVHLKELFMCCNKL-TELP----RGIER-----LTHLTHLALDQNQLKSI 138
Query 480 P 480
P
Sbjct 139 P 139
>8c7h_E I Transforming growth factor beta activator LRRC32
Length=601
Score = 66.6 bits (161), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 116/485 (24%), Positives = 194/485 (40%), Gaps = 79/485 (16%)
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL--NNVQLGP 235
LS N+++++ + L + ++L+ L+LS+N+I PG F A+ L L L N + +
Sbjct 37 LSGNQLRSILASPLGFY--TALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMAT 94
Query 236 SLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
+L+ L + +L LS + L + LG + +L L L+ N+L + +F
Sbjct 95 ALSAGGLGPLPR--VTSLDLSGNSLYSGLLERLLG-EAPSLHTLSLAENSLTRLTRHTFR 151
Query 296 WLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLK 355
+P LE L N + + + GL + +LNL R+ SL I DFS Q L+
Sbjct 152 DMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRN---------SLTCISDFSLQQLR 202
Query 356 CLEHLNMEDNDIPGIK-SNMFTGLINLKYLSLSNS----FTSLRTLTNETFVSLAHSPLH 410
L+ + N I + ++ L +L L + F L L +++L+++ +
Sbjct 203 VLD---LSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLIR 259
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQ 470
+ I + + W R L + + LSYN+ ++
Sbjct 260 LPXXXXXXXXXIHAPSEGW---------SAXXXXXXXXXXXXRPLSQLLNLDLSYNE-IE 309
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLE 530
L +SF + L +L L+LS N + L L
Sbjct 310 LIPDSF-------------------------LEHLTSLCFLNLSRNCLRTFEARRLGSLP 344
Query 531 KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKI 590
L +LDL HN L L A + L L L L+ N ++P F +L L+
Sbjct 345 CLMLLDLSHNALETLELGA---------RALGSLRTLLLQGNALRDLPPYTFANLASLQR 395
Query 591 IDLGLNNLN---------TLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
++L N ++ F SL+SL+L N I + F LTELD
Sbjct 396 LNLQGNRVSPXXXXXXXXXXXXXAFXXITSLRSLSLVDNEIELLRAGAF--LHTPLTELD 453
Query 642 MRFNP 646
+ NP
Sbjct 454 LSSNP 458
Score = 65.9 bits (159), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 138/535 (26%), Positives = 214/535 (40%), Gaps = 95/535 (18%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C L L QVP LP + L+L+ NQLR + A+ Y+ L LD+ N IS L+P Q
Sbjct 16 CQVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQ 75
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L+L HN L+ M+ ++ P + + +LDLS
Sbjct 76 ALTHLEHLSLAHNRLA------------------MATALSAGGLGPLPR---VTSLDLSG 114
Query 157 NGLSSTKLGTQV-QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
N L S L + + +L L L+ N + L +L++L+L SN + + G
Sbjct 115 NSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMP--ALEQLDLHSNVLMDIEDG 172
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTN 275
F + RL +L+LS + L+ S+ +
Sbjct 173 AFEGLPRL---------------------------THLNLSRNSLTCISDFSL-----QQ 200
Query 276 LTMLDLSYNNLNVVGNDSFAWLP-QLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
L +LDLS N++ S QL + L N + H L L + YLNL +
Sbjct 201 LRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHF--PDLAALPRLIYLNLSNNLI 258
Query 335 K-QSISLASLPKIDDFSFQW----------------LKCLEHLNMEDNDIPGIKSNMFTG 377
+ I S W L L +L++ N+I I +
Sbjct 259 RLPXXXXXXXXXIHAPSEGWSAXXXXXXXXXXXXRPLSQLLNLDLSYNEIELIPDSFLEH 318
Query 378 LINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
L +L +L+LS + LRT SL L +L+L+ N + +E A + LG L L
Sbjct 319 LTSLCFLNLSRN--CLRTFEARRLGSLPC--LMLLDLSHNALETLELGARA-LGSLRTLL 373
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKY---------LQLTRNSFALVPSLQRLMLR 488
L N + ++L + L ++ + L N+ +F + SL+ L L
Sbjct 374 LQGNAL-RDLPPYTFANLASLQRLNLQGNRVSPXXXXXXXXXXXXXAFXXITSLRSLSLV 432
Query 489 RVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK-LEILDLQHNNL 542
++ + + P LT LDLS+N + L GLE LE+L LQ N L
Sbjct 433 DNEIELLRAGAFLHTP---LTELDLSSNPGLEVATGALGGLEASLEVLALQGNGL 484
Score = 43.1 bits (100), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 57/212 (27%), Positives = 85/212 (40%), Gaps = 35/212 (17%)
Query 467 KYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPF-QPLRNLTILDLSNNNIANINDDM 525
+ L L + L P + L L L+++ +SP F LR+L DLS N I+ +
Sbjct 17 QVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHL---DLSTNEISFLQPGA 73
Query 526 LEGLEKLEILDLQHNNLARLWKHANPG-GPIYFLKGLS-------------------HLH 565
+ L LE L L HN LA + G GP+ + L LH
Sbjct 74 FQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLH 133
Query 566 ILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSV 625
L+L N + F+D+ L+ +DL N L + F L LNL +N +T +
Sbjct 134 TLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCI 193
Query 626 EKKVFGPAFRNLTELDMRFNPFDCTCESIAWF 657
+ + L LD+ +C SI F
Sbjct 194 SDF----SLQQLRVLDL-------SCNSIEAF 214
>3e6j_A A Variable lymphocyte receptor diversity region
Length=229
Score = 63.9 bits (154), Expect = 8e-10, Method: Compositional matrix adjust.
Identities = 50/158 (32%), Positives = 72/158 (46%), Gaps = 31/158 (20%)
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
+IL L N + +L PG L +L L L SN +PV VF L +L ++D
Sbjct 43 QILYLHDNQITKL----EPG----VFDSLINLKELYLGSNQLGALPVGVFDSLTQLTVLD 94
Query 593 LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE-------------------KKVFGPA 633
LG N L LP++VF+ V LK L + N +T + K + A
Sbjct 95 LGTNQLTVLPSAVFDRLVHLKELFMCCNKLTELPRGIERLTHLTHLALDQNQLKSIPHGA 154
Query 634 FRNLTELDMRF---NPFDCTCESIAWFVNWINETHTNI 668
F L+ L + NP+DC C I + NW+ + HT+I
Sbjct 155 FDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD-HTSI 191
Score = 55.8 bits (133), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 45/160 (28%), Positives = 69/160 (43%), Gaps = 1/160 (1%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLD 81
A+ ++C+ S DC + VP +PTN +L L NQ+ +L F L L
Sbjct 11 AACPSQCSCSGTTVDCRSKRHASVPAGIPTNAQILYLHDNQITKLEPGVFDSLINLKELY 70
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNN 141
+G N + L + L L VL+L N+L+ L F +L EL + N + ++
Sbjct 71 LGSNQLGALPVGVFDSLTQLTVLDLGTNQLTVLPSAVFDRLVHLKELFMCCNKLTELPRG 130
Query 142 PFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
+ +L L L N L S G +L +L L N
Sbjct 131 -IERLTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGN 169
Score = 37.0 bits (84), Expect = 0.56, Method: Compositional matrix adjust.
Identities = 38/121 (31%), Positives = 60/121 (50%), Gaps = 14/121 (12%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I ++ +F LINLK L L ++ L L F SL L +L+L N++
Sbjct 45 LYLHDNQITKLEPGVFDSLINLKELYLGSN--QLGALPVGVFDSLTQ--LTVLDLGTNQL 100
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALV 479
+ + S F L HL+ L + N++ EL RG+E L++ +L L +N +
Sbjct 101 TVLPSAVFDRLVHLKELFMCCNKL-TELP----RGIER-----LTHLTHLALDQNQLKSI 150
Query 480 P 480
P
Sbjct 151 P 151
>1p8v_A A Platelet glycoprotein Ib alpha chain
Length=287
Score = 64.7 bits (156), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 75/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRDLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSL 184
Score = 60.8 bits (146), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 49/161 (30%), Positives = 77/161 (48%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L NNL LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 44/145 (30%), Positives = 71/145 (49%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NNN+ +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNNLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 61/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N++ ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 40.8 bits (94), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>1m10_B B Glycoprotein Ib alpha
Length=290
Score = 64.7 bits (156), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 76/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C +LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRQLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSL 184
Score = 59.3 bits (142), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 48/161 (30%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L N L LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 60/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N + ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 43.5 bits (101), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 43/145 (30%), Positives = 70/145 (48%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NN + +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNQLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 41.6 bits (96), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 52/111 (47%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N+L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>1qyy_A A Platelet glycoprotein Ib alpha chain
Length=290
Score = 64.7 bits (156), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 75/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRAELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSL 184
Score = 60.8 bits (146), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 49/161 (30%), Positives = 77/161 (48%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L NNL LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 44/145 (30%), Positives = 71/145 (49%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRAELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NNN+ +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNNLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 45.4 bits (106), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 43/130 (33%), Positives = 61/130 (47%), Gaps = 2/130 (2%)
Query 36 DCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
D + L QV LP + L+L+HNQL+ LP T LT LDV FN ++ L
Sbjct 63 DRAELTKLQVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGAL 120
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
+ L L+ L L+ NEL L L +L L +N++ ++ +NL TL L
Sbjct 121 RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ 180
Query 156 HNGLSSTKLG 165
N L + G
Sbjct 181 ENSLYTIPKG 190
Score = 40.8 bits (94), Expect = 0.052, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>1qyy_B G Platelet glycoprotein Ib alpha chain
Length=290
Score = 64.7 bits (156), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 75/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRAELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSL 184
Score = 60.8 bits (146), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 49/161 (30%), Positives = 77/161 (48%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L NNL LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 44/145 (30%), Positives = 71/145 (49%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRAELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NNN+ +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNNLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 45.4 bits (106), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 43/130 (33%), Positives = 61/130 (47%), Gaps = 2/130 (2%)
Query 36 DCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
D + L QV LP + L+L+HNQL+ LP T LT LDV FN ++ L
Sbjct 63 DRAELTKLQVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGAL 120
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
+ L L+ L L+ NEL L L +L L +N++ ++ +NL TL L
Sbjct 121 RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ 180
Query 156 HNGLSSTKLG 165
N L + G
Sbjct 181 ENSLYTIPKG 190
Score = 40.8 bits (94), Expect = 0.052, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>1p9a_A G Platelet glycoprotein Ib alpha chain precursor
Length=290
Score = 64.7 bits (156), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 75/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRAELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSL 184
Score = 60.8 bits (146), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 49/161 (30%), Positives = 77/161 (48%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L NNL LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 44/145 (30%), Positives = 71/145 (49%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRAELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NNN+ +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNNLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 45.4 bits (106), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 43/130 (33%), Positives = 61/130 (47%), Gaps = 2/130 (2%)
Query 36 DCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
D + L QV LP + L+L+HNQL+ LP T LT LDV FN ++ L
Sbjct 63 DRAELTKLQVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGAL 120
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
+ L L+ L L+ NEL L L +L L +N++ ++ +NL TL L
Sbjct 121 RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ 180
Query 156 HNGLSSTKLG 165
N L + G
Sbjct 181 ENSLYTIPKG 190
Score = 40.8 bits (94), Expect = 0.052, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>6xfq_A G Platelet glycoprotein Ib alpha chain
Length=305
Score = 64.7 bits (156), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 76/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C +LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRQLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSL 184
Score = 59.3 bits (142), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 48/161 (30%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L N L LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 60/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N + ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 43.9 bits (102), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 43/145 (30%), Positives = 70/145 (48%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NN + +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNQLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 41.6 bits (96), Expect = 0.028, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 52/111 (47%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N+L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>5ufd_B B RBC36
Length=229
Score = 63.5 bits (153), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 50/158 (32%), Positives = 72/158 (46%), Gaps = 31/158 (20%)
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
+IL L N + +L PG L +L L L SN +PV VF L +L ++D
Sbjct 43 QILYLHDNQITKL----EPG----VFDSLINLKELYLGSNQLGALPVGVFDSLTQLTVLD 94
Query 593 LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE-------------------KKVFGPA 633
LG N L LP++VF+ V LK L + N +T + K + A
Sbjct 95 LGTNQLTVLPSAVFDRLVHLKELFMCCNKLTELPRGIERLTHLTHLALDQNQLKSIPHGA 154
Query 634 FRNLTELDMRF---NPFDCTCESIAWFVNWINETHTNI 668
F L+ L + NP+DC C I + NW+ + HT+I
Sbjct 155 FDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD-HTSI 191
Score = 53.9 bits (128), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 67/156 (43%), Gaps = 1/156 (1%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DC + VP +PTN +L L NQ+ +L F L L +G N
Sbjct 15 SQCSCSGTTVDCRSKRHASVPAGIPTNAQILYLHDNQITKLEPGVFDSLINLKELYLGSN 74
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ L + L L VL+L N+L+ L F +L EL + N + ++ +
Sbjct 75 QLGALPVGVFDSLTQLTVLDLGTNQLTVLPSAVFDRLVHLKELFMCCNKLTELPRG-IER 133
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
+L L L N L S G +L +L L N
Sbjct 134 LTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGN 169
Score = 37.4 bits (85), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 38/121 (31%), Positives = 60/121 (50%), Gaps = 14/121 (12%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I ++ +F LINLK L L ++ L L F SL L +L+L N++
Sbjct 45 LYLHDNQITKLEPGVFDSLINLKELYLGSN--QLGALPVGVFDSLTQ--LTVLDLGTNQL 100
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALV 479
+ + S F L HL+ L + N++ EL RG+E L++ +L L +N +
Sbjct 101 TVLPSAVFDRLVHLKELFMCCNKL-TELP----RGIER-----LTHLTHLALDQNQLKSI 150
Query 480 P 480
P
Sbjct 151 P 151
>1sq0_B B Platelet glycoprotein Ib alpha chain (Glycoprotein Ibalpha)
(GP-Ib alpha) (GPIbA) (GPIb-alpha) (CD42B-alpha) (CD42B)
[Contains: Glycocalicin]
Length=288
Score = 64.7 bits (156), Expect = 9e-10, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 75/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRDLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNDLTELPAGLLNGLENLDTLLLQENSL 184
Score = 59.7 bits (143), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 48/161 (30%), Positives = 77/161 (48%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L N+L LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNDLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 60/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N + ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNDLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 43/145 (30%), Positives = 71/145 (49%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NN++ +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNDLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 41.6 bits (96), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 52/111 (47%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N+L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNDLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>5ufd_A A RBC36
Length=229
Score = 63.5 bits (153), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 50/158 (32%), Positives = 72/158 (46%), Gaps = 31/158 (20%)
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
+IL L N + +L PG L +L L L SN +PV VF L +L ++D
Sbjct 43 QILYLHDNQITKL----EPG----VFDSLINLKELYLGSNQLGALPVGVFDSLTQLTVLD 94
Query 593 LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE-------------------KKVFGPA 633
LG N L LP++VF+ V LK L + N +T + K + A
Sbjct 95 LGTNQLTVLPSAVFDRLVHLKELFMCCNKLTELPRGIERLTHLTHLALDQNQLKSIPHGA 154
Query 634 FRNLTELDMRF---NPFDCTCESIAWFVNWINETHTNI 668
F L+ L + NP+DC C I + NW+ + HT+I
Sbjct 155 FDRLSSLTHAYLFGNPWDCECRDIMYLRNWVAD-HTSI 191
Score = 53.9 bits (128), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 44/156 (28%), Positives = 67/156 (43%), Gaps = 1/156 (1%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DC + VP +PTN +L L NQ+ +L F L L +G N
Sbjct 15 SQCSCSGTTVDCRSKRHASVPAGIPTNAQILYLHDNQITKLEPGVFDSLINLKELYLGSN 74
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ L + L L VL+L N+L+ L F +L EL + N + ++ +
Sbjct 75 QLGALPVGVFDSLTQLTVLDLGTNQLTVLPSAVFDRLVHLKELFMCCNKLTELPRG-IER 133
Query 146 QKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
+L L L N L S G +L +L L N
Sbjct 134 LTHLTHLALDQNQLKSIPHGAFDRLSSLTHAYLFGN 169
Score = 37.0 bits (84), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 38/121 (31%), Positives = 60/121 (50%), Gaps = 14/121 (12%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I ++ +F LINLK L L ++ L L F SL L +L+L N++
Sbjct 45 LYLHDNQITKLEPGVFDSLINLKELYLGSN--QLGALPVGVFDSLTQ--LTVLDLGTNQL 100
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALV 479
+ + S F L HL+ L + N++ EL RG+E L++ +L L +N +
Sbjct 101 TVLPSAVFDRLVHLKELFMCCNKL-TELP----RGIER-----LTHLTHLALDQNQLKSI 150
Query 480 P 480
P
Sbjct 151 P 151
>1m0z_B B Glycoprotein Ib alpha
Length=290
Score = 64.3 bits (155), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 76/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C +LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRQLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSL 184
Score = 59.3 bits (142), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 48/161 (30%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L N L LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 60/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N + ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 43.5 bits (101), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 43/145 (30%), Positives = 70/145 (48%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NN + +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNQLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 41.2 bits (95), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 52/111 (47%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N+L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>1ook_D G Platelet glycoprotein Ib alpha chain precursor
Length=298
Score = 64.7 bits (156), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 75/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRAELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSL 184
Score = 60.5 bits (145), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 49/161 (30%), Positives = 77/161 (48%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L NNL LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 44/145 (30%), Positives = 71/145 (49%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRAELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NNN+ +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNNLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 45.4 bits (106), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 43/130 (33%), Positives = 61/130 (47%), Gaps = 2/130 (2%)
Query 36 DCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
D + L QV LP + L+L+HNQL+ LP T LT LDV FN ++ L
Sbjct 63 DRAELTKLQVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGAL 120
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
+ L L+ L L+ NEL L L +L L +N++ ++ +NL TL L
Sbjct 121 RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ 180
Query 156 HNGLSSTKLG 165
N L + G
Sbjct 181 ENSLYTIPKG 190
Score = 40.4 bits (93), Expect = 0.056, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>1gwb_A A PLATELET GLYCOPROTEIN IB ALPHA CHAIN
Length=293
Score = 64.3 bits (155), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 75/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 11 ASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 70
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 71 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 130
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 131 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSL 185
Score = 60.8 bits (146), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 49/161 (30%), Positives = 77/161 (48%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 80 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 130
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L NNL LPA + N +L +L LQ+N + ++ K
Sbjct 131 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPK 190
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 191 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 228
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 44/145 (30%), Positives = 71/145 (49%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 53 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 108
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NNN+ +
Sbjct 109 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNNLTELP 165
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 166 AGLLNGLENLDTLLLQENSLYTIPK 190
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 61/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 66 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 122
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N++ ++ +NL TL L
Sbjct 123 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQE 182
Query 157 NGLSSTKLG 165
N L + G
Sbjct 183 NSLYTIPKG 191
Score = 40.4 bits (93), Expect = 0.054, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 84 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 142
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 143 GLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 193
>4cnc_A A TROPHOBLAST GLYCOPROTEIN
Length=299
Score = 64.7 bits (156), Expect = 1e-09, Method: Composition-based stats.
Identities = 60/211 (28%), Positives = 96/211 (45%), Gaps = 11/211 (5%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTR---YSQLTSLDVG 83
+C+ + C + LT+VP DLP + L LT NQL LPA F R ++L +L++
Sbjct 11 ECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELAALNLS 70
Query 84 FNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
+ + ++ + LP L+ L+L HN L+ LS FAF S ++ I N+
Sbjct 71 GSRLDEVRAGAFEHLPSLRQLDLSHNPLADLS--PFAFSXXXXXXSAPSPLVELILNH-- 126
Query 144 VKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKL 202
+ S G+ L L+ L+ L L++N L D+ A SL+ L
Sbjct 127 IVPPEXXXXXRSFEGMVVAALLAGRALQGLRRLELASNHFLYLPR---DVLAQLPSLRHL 183
Query 203 ELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
+LS+N + + F + L L L + L
Sbjct 184 DLSNNSLVSLTYVSFRNLTHLESLHLEDNAL 214
Score = 47.4 bits (111), Expect = 4e-04, Method: Composition-based stats.
Identities = 62/239 (26%), Positives = 91/239 (38%), Gaps = 55/239 (23%)
Query 464 SYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIND 523
+Y + L LT N A++P+ RR PL L L+LS + + +
Sbjct 35 AYVRNLFLTGNQLAVLPA--GAFARR-------------PPLAELAALNLSGSRLDEVRA 79
Query 524 DMLEGLEKLEILDLQHNNLARLWKHA--------NPGGPIYFL----------------- 558
E L L LDL HN LA L A + P+ L
Sbjct 80 GAFEHLPSLRQLDLSHNPLADLSPFAFSXXXXXXSAPSPLVELILNHIVPPEXXXXXRSF 139
Query 559 -----------KGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
+ L L L L SN F +P +V L L+ +DL N+L +L F
Sbjct 140 EGMVVAALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFR 199
Query 608 NQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRF--NPFDCTCESIAWFVNWINET 664
N L+SL+L+ N + + + L + + NP+ C C +A V W+ ET
Sbjct 200 NLTHLESLHLEDNALKVLHNGTLA-ELQGLPHIRVFLDNNPWVCDCH-MADMVTWLKET 256
Score = 35.0 bits (79), Expect = 3.6, Method: Composition-based stats.
Identities = 21/73 (29%), Positives = 38/73 (52%), Gaps = 0/73 (0%)
Query 77 LTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ 136
L L++ N L ++ +LP L+ L+L +N L L+ +F T+L LHL N+++
Sbjct 156 LRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHLESLHLEDNALK 215
Query 137 KIKNNPFVKQKNL 149
+ N + + L
Sbjct 216 VLHNGTLAELQGL 228
>4v2d_A A FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2
Length=326
Score = 64.7 bits (156), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 81/282 (29%), Positives = 129/282 (46%), Gaps = 26/282 (9%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C C+ LT VP +P +TVL L +NQ+ A + S+ +
Sbjct 5 CRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINN--AGFPAELHNVQSVHTVYLYG 62
Query 88 SKLEPELCQKLPM-LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPFV 144
++L+ E LP ++VL+LQ N + +S A L ELHL NSI +++ F
Sbjct 63 NQLD-EFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFR 121
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLE 203
+ +L L LS N LSS +G V +LQEL + N+I + F N +SL++L
Sbjct 122 EAISLKLLFLSKNHLSSVPVGLPV---DLQELRVDENRIAVISDMA---FQNLTSLERLI 175
Query 204 LSSNQI--KEFSPGCFHAIGRL--FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
+ N + K + G F + +L F + N++ P +L T + L L ++Q
Sbjct 176 VDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPP-------DLPGTHLIRLYLQDNQ 228
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
++ T F L+ L LD+S N L ++ F L L+
Sbjct 229 INHIPLTAFANLR--KLERLDISNNQLRMLTQGVFDHLSNLK 268
Score = 54.3 bits (129), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 78/293 (27%), Positives = 119/293 (41%), Gaps = 58/293 (20%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
+ +L+L +N I I A + L LE L L N I G E + F +S K
Sbjct 76 VRVLHLQENNIQTISRAALAQLLKLEELHLDDNSIST--VGVE----DGAFREAISL-KL 128
Query 469 LQLTRNSFALVP-----SLQRLML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN- 520
L L++N + VP LQ L + R+A+ S FQ L +L L + N + N
Sbjct 129 LFLSKNHLSSVPVGLPVDLQELRVDENRIAV----ISDMAFQNLTSLERLIVDGNLLTNK 184
Query 521 -INDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I + L KL+ + N+L+ H P P +HL L L+ N + IP+
Sbjct 185 GIAEGTFSHLTKLKEFSIVRNSLS----HPPPDLPG------THLIRLYLQDNQINHIPL 234
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F +L +L+ +D+ N L L VF++ NL +
Sbjct 235 TAFANLRKLERLDISNNQLRMLTQGVFDH-------------------------LSNLKQ 269
Query 640 LDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFD 692
L R NP+ C C SI W W+ +++ ++C P G VR +
Sbjct 270 LTARNNPWFCDC-SIKWVTEWLKYIPSSLN--VRGFMCQGPEQVRGMAVRALN 319
Score = 41.6 bits (96), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 57/217 (26%), Positives = 95/217 (44%), Gaps = 33/217 (15%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKL 98
+L + P +LP N+ VL+L N ++ + A + +L L + N+IS +E ++
Sbjct 64 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREA 123
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
LK+L L N LS + +L EL + N I I + F +L L + N
Sbjct 124 ISLKLLFLSKNHLSSVP---VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNL 180
Query 159 LSSTKL--GTQVQLENLQE----------------------LLLSNNKIQALKSEELDIF 194
L++ + GT L L+E L L +N+I + L F
Sbjct 181 LTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIP---LTAF 237
Query 195 AN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AN L++L++S+NQ++ + G F + L L N
Sbjct 238 ANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARN 274
Score = 41.2 bits (95), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 42/140 (30%), Positives = 67/140 (48%), Gaps = 11/140 (8%)
Query 501 PFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG 560
P +N+ +L L NNI I+ L L KLE L L N+++ + F +
Sbjct 69 PMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDG-----AFREA 123
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
+S L +L L N +PV + DL EL++ + N + + F N SL+ L + N
Sbjct 124 IS-LKLLFLSKNHLSSVPVGLPVDLQELRVDE---NRIAVISDMAFQNLTSLERLIVDGN 179
Query 621 LITSVEKKVFGPAFRNLTEL 640
L+T+ K + F +LT+L
Sbjct 180 LLTN--KGIAEGTFSHLTKL 197
Score = 37.0 bits (84), Expect = 0.82, Method: Compositional matrix adjust.
Identities = 52/189 (28%), Positives = 82/189 (43%), Gaps = 30/189 (16%)
Query 275 NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
N+ +L L NN+ + + A L +LE L+ N+I + G F ++LK F
Sbjct 75 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVED--GAFR-EAISLKLLFL 131
Query 335 KQSISLASLP------------------KIDDFSFQWLKCLEHLNMEDNDI--PGIKSNM 374
++ L+S+P I D +FQ L LE L ++ N + GI
Sbjct 132 SKN-HLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 190
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
F+ L LK F+ +R + L + L L L N+I+ I AF+ L LE
Sbjct 191 FSHLTKLK------EFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLE 244
Query 435 VLDLGLNEI 443
LD+ N++
Sbjct 245 RLDISNNQL 253
Score = 37.0 bits (84), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 54/202 (27%), Positives = 89/202 (44%), Gaps = 10/202 (5%)
Query 345 KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
++D+F K + L++++N+I I L+ L+ L L ++ S+ T+ E
Sbjct 64 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDN--SISTVGVEDGAFR 121
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN-IFEIYL 463
L +L L+KN +S + L L V D + ++ Q LE I + L
Sbjct 122 EAISLKLLFLSKNHLSSVPVGLPVDLQELRV-DENRIAVISDMAFQNLTSLERLIVDGNL 180
Query 464 SYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIND 523
NK + +F+ + L+ + R +L S P P P +L L L +N I +I
Sbjct 181 LTNK--GIAEGTFSHLTKLKEFSIVRNSL----SHPPPDLPGTHLIRLYLQDNQINHIPL 234
Query 524 DMLEGLEKLEILDLQHNNLARL 545
L KLE LD+ +N L L
Sbjct 235 TAFANLRKLERLDISNNQLRML 256
Score = 36.6 bits (83), Expect = 1.00, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 59/142 (42%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ VP LP ++ L + N++ + F + L L V N ++ + L
Sbjct 136 LSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLT 195
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
LK ++ N LS T+L L+L N I I F + L LD+S+N L
Sbjct 196 KLKEFSIVRNSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQL 253
Query 160 SSTKLGTQVQLENLQELLLSNN 181
G L NL++L NN
Sbjct 254 RMLTQGVFDHLSNLKQLTARNN 275
>1gwb_B B PLATELET GLYCOPROTEIN IB ALPHA CHAIN
Length=293
Score = 64.3 bits (155), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 75/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 11 ASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRCELTK 70
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 71 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 130
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 131 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSL 185
Score = 60.5 bits (145), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 49/161 (30%), Positives = 77/161 (48%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 80 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 130
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L NNL LPA + N +L +L LQ+N + ++ K
Sbjct 131 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPK 190
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 191 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 228
Score = 45.4 bits (106), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 44/145 (30%), Positives = 71/145 (49%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 53 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 108
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NNN+ +
Sbjct 109 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNNLTELP 165
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 166 AGLLNGLENLDTLLLQENSLYTIPK 190
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 61/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 66 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 122
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N++ ++ +NL TL L
Sbjct 123 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQE 182
Query 157 NGLSSTKLG 165
N L + G
Sbjct 183 NSLYTIPKG 191
Score = 40.4 bits (93), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 84 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 142
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 143 GLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 193
>4v2c_C C FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2
Length=328
Score = 64.7 bits (156), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 81/282 (29%), Positives = 129/282 (46%), Gaps = 26/282 (9%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C C+ LT VP +P +TVL L +NQ+ A + S+ +
Sbjct 6 CRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINN--AGFPAELHNVQSVHTVYLYG 63
Query 88 SKLEPELCQKLPM-LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPFV 144
++L+ E LP ++VL+LQ N + +S A L ELHL NSI +++ F
Sbjct 64 NQLD-EFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFR 122
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLE 203
+ +L L LS N LSS +G V +LQEL + N+I + F N +SL++L
Sbjct 123 EAISLKLLFLSKNHLSSVPVGLPV---DLQELRVDENRIAVISDMA---FQNLTSLERLI 176
Query 204 LSSNQI--KEFSPGCFHAIGRL--FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
+ N + K + G F + +L F + N++ P +L T + L L ++Q
Sbjct 177 VDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPP-------DLPGTHLIRLYLQDNQ 229
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
++ T F L+ L LD+S N L ++ F L L+
Sbjct 230 INHIPLTAFANLR--KLERLDISNNQLRMLTQGVFDHLSNLK 269
Score = 53.9 bits (128), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 78/290 (27%), Positives = 118/290 (41%), Gaps = 58/290 (20%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
+ +L+L +N I I A + L LE L L N I G E + F +S K
Sbjct 77 VRVLHLQENNIQTISRAALAQLLKLEELHLDDNSIST--VGVE----DGAFREAISL-KL 129
Query 469 LQLTRNSFALVP-----SLQRLML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN- 520
L L++N + VP LQ L + R+A+ S FQ L +L L + N + N
Sbjct 130 LFLSKNHLSSVPVGLPVDLQELRVDENRIAV----ISDMAFQNLTSLERLIVDGNLLTNK 185
Query 521 -INDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I + L KL+ + N+L+ H P P +HL L L+ N + IP+
Sbjct 186 GIAEGTFSHLTKLKEFSIVRNSLS----HPPPDLPG------THLIRLYLQDNQINHIPL 235
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F +L +L+ +D+ N L L VF++ NL +
Sbjct 236 TAFANLRKLERLDISNNQLRMLTQGVFDH-------------------------LSNLKQ 270
Query 640 LDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
L R NP+ C C SI W W+ +++ ++C P G VR
Sbjct 271 LTARNNPWFCDC-SIKWVTEWLKYIPSSLN--VRGFMCQGPEQVRGMAVR 317
Score = 41.6 bits (96), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 57/217 (26%), Positives = 95/217 (44%), Gaps = 33/217 (15%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKL 98
+L + P +LP N+ VL+L N ++ + A + +L L + N+IS +E ++
Sbjct 65 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREA 124
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
LK+L L N LS + +L EL + N I I + F +L L + N
Sbjct 125 ISLKLLFLSKNHLSSVP---VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNL 181
Query 159 LSSTKL--GTQVQLENLQE----------------------LLLSNNKIQALKSEELDIF 194
L++ + GT L L+E L L +N+I + L F
Sbjct 182 LTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIP---LTAF 238
Query 195 AN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AN L++L++S+NQ++ + G F + L L N
Sbjct 239 ANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARN 275
Score = 41.2 bits (95), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 42/140 (30%), Positives = 67/140 (48%), Gaps = 11/140 (8%)
Query 501 PFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG 560
P +N+ +L L NNI I+ L L KLE L L N+++ + F +
Sbjct 70 PMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDG-----AFREA 124
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
+S L +L L N +PV + DL EL++ + N + + F N SL+ L + N
Sbjct 125 IS-LKLLFLSKNHLSSVPVGLPVDLQELRVDE---NRIAVISDMAFQNLTSLERLIVDGN 180
Query 621 LITSVEKKVFGPAFRNLTEL 640
L+T+ K + F +LT+L
Sbjct 181 LLTN--KGIAEGTFSHLTKL 198
Score = 37.0 bits (84), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 52/189 (28%), Positives = 82/189 (43%), Gaps = 30/189 (16%)
Query 275 NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
N+ +L L NN+ + + A L +LE L+ N+I + G F ++LK F
Sbjct 76 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVED--GAFR-EAISLKLLFL 132
Query 335 KQSISLASLP------------------KIDDFSFQWLKCLEHLNMEDNDI--PGIKSNM 374
++ L+S+P I D +FQ L LE L ++ N + GI
Sbjct 133 SKN-HLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 191
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
F+ L LK F+ +R + L + L L L N+I+ I AF+ L LE
Sbjct 192 FSHLTKLK------EFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLE 245
Query 435 VLDLGLNEI 443
LD+ N++
Sbjct 246 RLDISNNQL 254
Score = 37.0 bits (84), Expect = 0.96, Method: Compositional matrix adjust.
Identities = 54/202 (27%), Positives = 89/202 (44%), Gaps = 10/202 (5%)
Query 345 KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
++D+F K + L++++N+I I L+ L+ L L ++ S+ T+ E
Sbjct 65 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDN--SISTVGVEDGAFR 122
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN-IFEIYL 463
L +L L+KN +S + L L V D + ++ Q LE I + L
Sbjct 123 EAISLKLLFLSKNHLSSVPVGLPVDLQELRV-DENRIAVISDMAFQNLTSLERLIVDGNL 181
Query 464 SYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIND 523
NK + +F+ + L+ + R +L S P P P +L L L +N I +I
Sbjct 182 LTNK--GIAEGTFSHLTKLKEFSIVRNSL----SHPPPDLPGTHLIRLYLQDNQINHIPL 235
Query 524 DMLEGLEKLEILDLQHNNLARL 545
L KLE LD+ +N L L
Sbjct 236 TAFANLRKLERLDISNNQLRML 257
Score = 36.6 bits (83), Expect = 1.00, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 59/142 (42%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ VP LP ++ L + N++ + F + L L V N ++ + L
Sbjct 137 LSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLT 196
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
LK ++ N LS T+L L+L N I I F + L LD+S+N L
Sbjct 197 KLKEFSIVRNSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQL 254
Query 160 SSTKLGTQVQLENLQELLLSNN 181
G L NL++L NN
Sbjct 255 RMLTQGVFDHLSNLKQLTARNN 276
>4v2c_A A FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2
Length=328
Score = 64.7 bits (156), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 81/282 (29%), Positives = 129/282 (46%), Gaps = 26/282 (9%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C C+ LT VP +P +TVL L +NQ+ A + S+ +
Sbjct 6 CRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINN--AGFPAELHNVQSVHTVYLYG 63
Query 88 SKLEPELCQKLPM-LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPFV 144
++L+ E LP ++VL+LQ N + +S A L ELHL NSI +++ F
Sbjct 64 NQLD-EFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFR 122
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLE 203
+ +L L LS N LSS +G V +LQEL + N+I + F N +SL++L
Sbjct 123 EAISLKLLFLSKNHLSSVPVGLPV---DLQELRVDENRIAVISDMA---FQNLTSLERLI 176
Query 204 LSSNQI--KEFSPGCFHAIGRL--FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
+ N + K + G F + +L F + N++ P +L T + L L ++Q
Sbjct 177 VDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPP-------DLPGTHLIRLYLQDNQ 229
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
++ T F L+ L LD+S N L ++ F L L+
Sbjct 230 INHIPLTAFANLR--KLERLDISNNQLRMLTQGVFDHLSNLK 269
Score = 53.9 bits (128), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 78/290 (27%), Positives = 118/290 (41%), Gaps = 58/290 (20%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
+ +L+L +N I I A + L LE L L N I G E + F +S K
Sbjct 77 VRVLHLQENNIQTISRAALAQLLKLEELHLDDNSIST--VGVE----DGAFREAISL-KL 129
Query 469 LQLTRNSFALVP-----SLQRLML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN- 520
L L++N + VP LQ L + R+A+ S FQ L +L L + N + N
Sbjct 130 LFLSKNHLSSVPVGLPVDLQELRVDENRIAV----ISDMAFQNLTSLERLIVDGNLLTNK 185
Query 521 -INDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I + L KL+ + N+L+ H P P +HL L L+ N + IP+
Sbjct 186 GIAEGTFSHLTKLKEFSIVRNSLS----HPPPDLPG------THLIRLYLQDNQINHIPL 235
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F +L +L+ +D+ N L L VF++ NL +
Sbjct 236 TAFANLRKLERLDISNNQLRMLTQGVFDH-------------------------LSNLKQ 270
Query 640 LDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
L R NP+ C C SI W W+ +++ ++C P G VR
Sbjct 271 LTARNNPWFCDC-SIKWVTEWLKYIPSSLN--VRGFMCQGPEQVRGMAVR 317
Score = 41.6 bits (96), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 57/217 (26%), Positives = 95/217 (44%), Gaps = 33/217 (15%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKL 98
+L + P +LP N+ VL+L N ++ + A + +L L + N+IS +E ++
Sbjct 65 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREA 124
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
LK+L L N LS + +L EL + N I I + F +L L + N
Sbjct 125 ISLKLLFLSKNHLSSVP---VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNL 181
Query 159 LSSTKL--GTQVQLENLQE----------------------LLLSNNKIQALKSEELDIF 194
L++ + GT L L+E L L +N+I + L F
Sbjct 182 LTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIP---LTAF 238
Query 195 AN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AN L++L++S+NQ++ + G F + L L N
Sbjct 239 ANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARN 275
Score = 41.2 bits (95), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 42/140 (30%), Positives = 67/140 (48%), Gaps = 11/140 (8%)
Query 501 PFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG 560
P +N+ +L L NNI I+ L L KLE L L N+++ + F +
Sbjct 70 PMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDG-----AFREA 124
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
+S L +L L N +PV + DL EL++ + N + + F N SL+ L + N
Sbjct 125 IS-LKLLFLSKNHLSSVPVGLPVDLQELRVDE---NRIAVISDMAFQNLTSLERLIVDGN 180
Query 621 LITSVEKKVFGPAFRNLTEL 640
L+T+ K + F +LT+L
Sbjct 181 LLTN--KGIAEGTFSHLTKL 198
Score = 37.0 bits (84), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 52/189 (28%), Positives = 82/189 (43%), Gaps = 30/189 (16%)
Query 275 NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
N+ +L L NN+ + + A L +LE L+ N+I + G F ++LK F
Sbjct 76 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVED--GAFR-EAISLKLLFL 132
Query 335 KQSISLASLP------------------KIDDFSFQWLKCLEHLNMEDNDI--PGIKSNM 374
++ L+S+P I D +FQ L LE L ++ N + GI
Sbjct 133 SKN-HLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 191
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
F+ L LK F+ +R + L + L L L N+I+ I AF+ L LE
Sbjct 192 FSHLTKLK------EFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLE 245
Query 435 VLDLGLNEI 443
LD+ N++
Sbjct 246 RLDISNNQL 254
Score = 37.0 bits (84), Expect = 0.96, Method: Compositional matrix adjust.
Identities = 54/202 (27%), Positives = 89/202 (44%), Gaps = 10/202 (5%)
Query 345 KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
++D+F K + L++++N+I I L+ L+ L L ++ S+ T+ E
Sbjct 65 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDN--SISTVGVEDGAFR 122
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN-IFEIYL 463
L +L L+KN +S + L L V D + ++ Q LE I + L
Sbjct 123 EAISLKLLFLSKNHLSSVPVGLPVDLQELRV-DENRIAVISDMAFQNLTSLERLIVDGNL 181
Query 464 SYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIND 523
NK + +F+ + L+ + R +L S P P P +L L L +N I +I
Sbjct 182 LTNK--GIAEGTFSHLTKLKEFSIVRNSL----SHPPPDLPGTHLIRLYLQDNQINHIPL 235
Query 524 DMLEGLEKLEILDLQHNNLARL 545
L KLE LD+ +N L L
Sbjct 236 TAFANLRKLERLDISNNQLRML 257
Score = 36.6 bits (83), Expect = 1.00, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 59/142 (42%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ VP LP ++ L + N++ + F + L L V N ++ + L
Sbjct 137 LSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLT 196
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
LK ++ N LS T+L L+L N I I F + L LD+S+N L
Sbjct 197 KLKEFSIVRNSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQL 254
Query 160 SSTKLGTQVQLENLQELLLSNN 181
G L NL++L NN
Sbjct 255 RMLTQGVFDHLSNLKQLTARNN 276
>3pmh_C G Platelet glycoprotein Ib alpha chain
Length=302
Score = 64.3 bits (155), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 75/175 (43%), Gaps = 21/175 (12%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
SH +C LT +P DLP + T+L+L+ N L A Y++LT L++ ++K
Sbjct 10 ASHLEVNCDKRNLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLDRAELTK 69
Query 90 LE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTEL 128
L+ P L Q LP L VL++ N L+ L L EL
Sbjct 70 LQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGELQEL 129
Query 129 HLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
+L N ++ + L L L++N L+ G LENL LLL N +
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSL 184
Score = 60.1 bits (144), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 49/161 (30%), Positives = 77/161 (48%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L NNL LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 44/145 (30%), Positives = 71/145 (49%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRAELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NNN+ +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNNLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 43/130 (33%), Positives = 61/130 (47%), Gaps = 2/130 (2%)
Query 36 DCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
D + L QV LP + L+L+HNQL+ LP T LT LDV FN ++ L
Sbjct 63 DRAELTKLQVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGAL 120
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
+ L L+ L L+ NEL L L +L L +N++ ++ +NL TL L
Sbjct 121 RGLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQ 180
Query 156 HNGLSSTKLG 165
N L + G
Sbjct 181 ENSLYTIPKG 190
Score = 40.4 bits (93), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 51/111 (46%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNNLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>5ftt_B B LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2
Length=339
Score = 64.7 bits (156), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 81/282 (29%), Positives = 129/282 (46%), Gaps = 26/282 (9%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C C+ LT VP +P +TVL L +NQ+ A + S+ +
Sbjct 8 CRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINN--AGFPAELHNVQSVHTVYLYG 65
Query 88 SKLEPELCQKLPM-LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPFV 144
++L+ E LP ++VL+LQ N + +S A L ELHL NSI +++ F
Sbjct 66 NQLD-EFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFR 124
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLE 203
+ +L L LS N LSS +G V +LQEL + N+I + F N +SL++L
Sbjct 125 EAISLKLLFLSKNHLSSVPVGLPV---DLQELRVDENRIAVISDMA---FQNLTSLERLI 178
Query 204 LSSNQI--KEFSPGCFHAIGRL--FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
+ N + K + G F + +L F + N++ P +L T + L L ++Q
Sbjct 179 VDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPP-------DLPGTHLIRLYLQDNQ 231
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
++ T F L+ L LD+S N L ++ F L L+
Sbjct 232 INHIPLTAFANLR--KLERLDISNNQLRMLTQGVFDHLSNLK 271
Score = 53.9 bits (128), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 78/290 (27%), Positives = 118/290 (41%), Gaps = 58/290 (20%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
+ +L+L +N I I A + L LE L L N I G E + F +S K
Sbjct 79 VRVLHLQENNIQTISRAALAQLLKLEELHLDDNSIST--VGVE----DGAFREAISL-KL 131
Query 469 LQLTRNSFALVP-----SLQRLML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN- 520
L L++N + VP LQ L + R+A+ S FQ L +L L + N + N
Sbjct 132 LFLSKNHLSSVPVGLPVDLQELRVDENRIAV----ISDMAFQNLTSLERLIVDGNLLTNK 187
Query 521 -INDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I + L KL+ + N+L+ H P P +HL L L+ N + IP+
Sbjct 188 GIAEGTFSHLTKLKEFSIVRNSLS----HPPPDLPG------THLIRLYLQDNQINHIPL 237
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F +L +L+ +D+ N L L VF++ NL +
Sbjct 238 TAFANLRKLERLDISNNQLRMLTQGVFDH-------------------------LSNLKQ 272
Query 640 LDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
L R NP+ C C SI W W+ +++ ++C P G VR
Sbjct 273 LTARNNPWFCDC-SIKWVTEWLKYIPSSLN--VRGFMCQGPEQVRGMAVR 319
Score = 41.6 bits (96), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 57/217 (26%), Positives = 95/217 (44%), Gaps = 33/217 (15%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKL 98
+L + P +LP N+ VL+L N ++ + A + +L L + N+IS +E ++
Sbjct 67 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREA 126
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
LK+L L N LS + +L EL + N I I + F +L L + N
Sbjct 127 ISLKLLFLSKNHLSSVP---VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNL 183
Query 159 LSSTKL--GTQVQLENLQE----------------------LLLSNNKIQALKSEELDIF 194
L++ + GT L L+E L L +N+I + L F
Sbjct 184 LTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIP---LTAF 240
Query 195 AN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AN L++L++S+NQ++ + G F + L L N
Sbjct 241 ANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARN 277
Score = 41.2 bits (95), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 42/140 (30%), Positives = 67/140 (48%), Gaps = 11/140 (8%)
Query 501 PFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG 560
P +N+ +L L NNI I+ L L KLE L L N+++ + F +
Sbjct 72 PMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDG-----AFREA 126
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
+S L +L L N +PV + DL EL++ + N + + F N SL+ L + N
Sbjct 127 IS-LKLLFLSKNHLSSVPVGLPVDLQELRVDE---NRIAVISDMAFQNLTSLERLIVDGN 182
Query 621 LITSVEKKVFGPAFRNLTEL 640
L+T+ K + F +LT+L
Sbjct 183 LLTN--KGIAEGTFSHLTKL 200
Score = 37.0 bits (84), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 52/189 (28%), Positives = 82/189 (43%), Gaps = 30/189 (16%)
Query 275 NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
N+ +L L NN+ + + A L +LE L+ N+I + G F ++LK F
Sbjct 78 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVED--GAFR-EAISLKLLFL 134
Query 335 KQSISLASLP------------------KIDDFSFQWLKCLEHLNMEDNDI--PGIKSNM 374
++ L+S+P I D +FQ L LE L ++ N + GI
Sbjct 135 SKN-HLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 193
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
F+ L LK F+ +R + L + L L L N+I+ I AF+ L LE
Sbjct 194 FSHLTKLK------EFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLE 247
Query 435 VLDLGLNEI 443
LD+ N++
Sbjct 248 RLDISNNQL 256
Score = 37.0 bits (84), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 54/202 (27%), Positives = 89/202 (44%), Gaps = 10/202 (5%)
Query 345 KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
++D+F K + L++++N+I I L+ L+ L L ++ S+ T+ E
Sbjct 67 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDN--SISTVGVEDGAFR 124
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN-IFEIYL 463
L +L L+KN +S + L L V D + ++ Q LE I + L
Sbjct 125 EAISLKLLFLSKNHLSSVPVGLPVDLQELRV-DENRIAVISDMAFQNLTSLERLIVDGNL 183
Query 464 SYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIND 523
NK + +F+ + L+ + R +L S P P P +L L L +N I +I
Sbjct 184 LTNK--GIAEGTFSHLTKLKEFSIVRNSL----SHPPPDLPGTHLIRLYLQDNQINHIPL 237
Query 524 DMLEGLEKLEILDLQHNNLARL 545
L KLE LD+ +N L L
Sbjct 238 TAFANLRKLERLDISNNQLRML 259
Score = 36.6 bits (83), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 59/142 (42%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ VP LP ++ L + N++ + F + L L V N ++ + L
Sbjct 139 LSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLT 198
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
LK ++ N LS T+L L+L N I I F + L LD+S+N L
Sbjct 199 KLKEFSIVRNSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQL 256
Query 160 SSTKLGTQVQLENLQELLLSNN 181
G L NL++L NN
Sbjct 257 RMLTQGVFDHLSNLKQLTARNN 278
>5ftu_J J LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2
Length=339
Score = 64.7 bits (156), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 81/282 (29%), Positives = 129/282 (46%), Gaps = 26/282 (9%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C C+ LT VP +P +TVL L +NQ+ A + S+ +
Sbjct 8 CRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINN--AGFPAELHNVQSVHTVYLYG 65
Query 88 SKLEPELCQKLPM-LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPFV 144
++L+ E LP ++VL+LQ N + +S A L ELHL NSI +++ F
Sbjct 66 NQLD-EFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFR 124
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLE 203
+ +L L LS N LSS +G V +LQEL + N+I + F N +SL++L
Sbjct 125 EAISLKLLFLSKNHLSSVPVGLPV---DLQELRVDENRIAVISDMA---FQNLTSLERLI 178
Query 204 LSSNQI--KEFSPGCFHAIGRL--FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
+ N + K + G F + +L F + N++ P +L T + L L ++Q
Sbjct 179 VDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPP-------DLPGTHLIRLYLQDNQ 231
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
++ T F L+ L LD+S N L ++ F L L+
Sbjct 232 INHIPLTAFANLR--KLERLDISNNQLRMLTQGVFDHLSNLK 271
Score = 53.9 bits (128), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 78/290 (27%), Positives = 118/290 (41%), Gaps = 58/290 (20%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
+ +L+L +N I I A + L LE L L N I G E + F +S K
Sbjct 79 VRVLHLQENNIQTISRAALAQLLKLEELHLDDNSIST--VGVE----DGAFREAISL-KL 131
Query 469 LQLTRNSFALVP-----SLQRLML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN- 520
L L++N + VP LQ L + R+A+ S FQ L +L L + N + N
Sbjct 132 LFLSKNHLSSVPVGLPVDLQELRVDENRIAV----ISDMAFQNLTSLERLIVDGNLLTNK 187
Query 521 -INDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I + L KL+ + N+L+ H P P +HL L L+ N + IP+
Sbjct 188 GIAEGTFSHLTKLKEFSIVRNSLS----HPPPDLPG------THLIRLYLQDNQINHIPL 237
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F +L +L+ +D+ N L L VF++ NL +
Sbjct 238 TAFANLRKLERLDISNNQLRMLTQGVFDH-------------------------LSNLKQ 272
Query 640 LDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
L R NP+ C C SI W W+ +++ ++C P G VR
Sbjct 273 LTARNNPWFCDC-SIKWVTEWLKYIPSSLN--VRGFMCQGPEQVRGMAVR 319
Score = 41.6 bits (96), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 57/217 (26%), Positives = 95/217 (44%), Gaps = 33/217 (15%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKL 98
+L + P +LP N+ VL+L N ++ + A + +L L + N+IS +E ++
Sbjct 67 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREA 126
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
LK+L L N LS + +L EL + N I I + F +L L + N
Sbjct 127 ISLKLLFLSKNHLSSVP---VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNL 183
Query 159 LSSTKL--GTQVQLENLQE----------------------LLLSNNKIQALKSEELDIF 194
L++ + GT L L+E L L +N+I + L F
Sbjct 184 LTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIP---LTAF 240
Query 195 AN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AN L++L++S+NQ++ + G F + L L N
Sbjct 241 ANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARN 277
Score = 41.2 bits (95), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 42/140 (30%), Positives = 67/140 (48%), Gaps = 11/140 (8%)
Query 501 PFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG 560
P +N+ +L L NNI I+ L L KLE L L N+++ + F +
Sbjct 72 PMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDG-----AFREA 126
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
+S L +L L N +PV + DL EL++ + N + + F N SL+ L + N
Sbjct 127 IS-LKLLFLSKNHLSSVPVGLPVDLQELRVDE---NRIAVISDMAFQNLTSLERLIVDGN 182
Query 621 LITSVEKKVFGPAFRNLTEL 640
L+T+ K + F +LT+L
Sbjct 183 LLTN--KGIAEGTFSHLTKL 200
Score = 37.0 bits (84), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 52/189 (28%), Positives = 82/189 (43%), Gaps = 30/189 (16%)
Query 275 NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
N+ +L L NN+ + + A L +LE L+ N+I + G F ++LK F
Sbjct 78 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVED--GAFR-EAISLKLLFL 134
Query 335 KQSISLASLP------------------KIDDFSFQWLKCLEHLNMEDNDI--PGIKSNM 374
++ L+S+P I D +FQ L LE L ++ N + GI
Sbjct 135 SKN-HLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 193
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
F+ L LK F+ +R + L + L L L N+I+ I AF+ L LE
Sbjct 194 FSHLTKLK------EFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLE 247
Query 435 VLDLGLNEI 443
LD+ N++
Sbjct 248 RLDISNNQL 256
Score = 37.0 bits (84), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 54/202 (27%), Positives = 89/202 (44%), Gaps = 10/202 (5%)
Query 345 KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
++D+F K + L++++N+I I L+ L+ L L ++ S+ T+ E
Sbjct 67 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDN--SISTVGVEDGAFR 124
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN-IFEIYL 463
L +L L+KN +S + L L V D + ++ Q LE I + L
Sbjct 125 EAISLKLLFLSKNHLSSVPVGLPVDLQELRV-DENRIAVISDMAFQNLTSLERLIVDGNL 183
Query 464 SYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIND 523
NK + +F+ + L+ + R +L S P P P +L L L +N I +I
Sbjct 184 LTNK--GIAEGTFSHLTKLKEFSIVRNSL----SHPPPDLPGTHLIRLYLQDNQINHIPL 237
Query 524 DMLEGLEKLEILDLQHNNLARL 545
L KLE LD+ +N L L
Sbjct 238 TAFANLRKLERLDISNNQLRML 259
Score = 36.6 bits (83), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 59/142 (42%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ VP LP ++ L + N++ + F + L L V N ++ + L
Sbjct 139 LSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLT 198
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
LK ++ N LS T+L L+L N I I F + L LD+S+N L
Sbjct 199 KLKEFSIVRNSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQL 256
Query 160 SSTKLGTQVQLENLQELLLSNN 181
G L NL++L NN
Sbjct 257 RMLTQGVFDHLSNLKQLTARNN 278
>5ftu_F F LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2
Length=339
Score = 64.7 bits (156), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 81/282 (29%), Positives = 129/282 (46%), Gaps = 26/282 (9%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C C+ LT VP +P +TVL L +NQ+ A + S+ +
Sbjct 8 CRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINN--AGFPAELHNVQSVHTVYLYG 65
Query 88 SKLEPELCQKLPM-LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPFV 144
++L+ E LP ++VL+LQ N + +S A L ELHL NSI +++ F
Sbjct 66 NQLD-EFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFR 124
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLE 203
+ +L L LS N LSS +G V +LQEL + N+I + F N +SL++L
Sbjct 125 EAISLKLLFLSKNHLSSVPVGLPV---DLQELRVDENRIAVISDMA---FQNLTSLERLI 178
Query 204 LSSNQI--KEFSPGCFHAIGRL--FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
+ N + K + G F + +L F + N++ P +L T + L L ++Q
Sbjct 179 VDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPP-------DLPGTHLIRLYLQDNQ 231
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
++ T F L+ L LD+S N L ++ F L L+
Sbjct 232 INHIPLTAFANLR--KLERLDISNNQLRMLTQGVFDHLSNLK 271
Score = 53.9 bits (128), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 78/290 (27%), Positives = 118/290 (41%), Gaps = 58/290 (20%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
+ +L+L +N I I A + L LE L L N I G E + F +S K
Sbjct 79 VRVLHLQENNIQTISRAALAQLLKLEELHLDDNSIST--VGVE----DGAFREAISL-KL 131
Query 469 LQLTRNSFALVP-----SLQRLML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN- 520
L L++N + VP LQ L + R+A+ S FQ L +L L + N + N
Sbjct 132 LFLSKNHLSSVPVGLPVDLQELRVDENRIAV----ISDMAFQNLTSLERLIVDGNLLTNK 187
Query 521 -INDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I + L KL+ + N+L+ H P P +HL L L+ N + IP+
Sbjct 188 GIAEGTFSHLTKLKEFSIVRNSLS----HPPPDLPG------THLIRLYLQDNQINHIPL 237
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F +L +L+ +D+ N L L VF++ NL +
Sbjct 238 TAFANLRKLERLDISNNQLRMLTQGVFDH-------------------------LSNLKQ 272
Query 640 LDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
L R NP+ C C SI W W+ +++ ++C P G VR
Sbjct 273 LTARNNPWFCDC-SIKWVTEWLKYIPSSLN--VRGFMCQGPEQVRGMAVR 319
Score = 41.6 bits (96), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 57/217 (26%), Positives = 95/217 (44%), Gaps = 33/217 (15%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKL 98
+L + P +LP N+ VL+L N ++ + A + +L L + N+IS +E ++
Sbjct 67 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREA 126
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
LK+L L N LS + +L EL + N I I + F +L L + N
Sbjct 127 ISLKLLFLSKNHLSSVP---VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNL 183
Query 159 LSSTKL--GTQVQLENLQE----------------------LLLSNNKIQALKSEELDIF 194
L++ + GT L L+E L L +N+I + L F
Sbjct 184 LTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIP---LTAF 240
Query 195 AN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AN L++L++S+NQ++ + G F + L L N
Sbjct 241 ANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARN 277
Score = 41.2 bits (95), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 42/140 (30%), Positives = 67/140 (48%), Gaps = 11/140 (8%)
Query 501 PFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG 560
P +N+ +L L NNI I+ L L KLE L L N+++ + F +
Sbjct 72 PMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDG-----AFREA 126
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
+S L +L L N +PV + DL EL++ + N + + F N SL+ L + N
Sbjct 127 IS-LKLLFLSKNHLSSVPVGLPVDLQELRVDE---NRIAVISDMAFQNLTSLERLIVDGN 182
Query 621 LITSVEKKVFGPAFRNLTEL 640
L+T+ K + F +LT+L
Sbjct 183 LLTN--KGIAEGTFSHLTKL 200
Score = 37.0 bits (84), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 52/189 (28%), Positives = 82/189 (43%), Gaps = 30/189 (16%)
Query 275 NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
N+ +L L NN+ + + A L +LE L+ N+I + G F ++LK F
Sbjct 78 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVED--GAFR-EAISLKLLFL 134
Query 335 KQSISLASLP------------------KIDDFSFQWLKCLEHLNMEDNDI--PGIKSNM 374
++ L+S+P I D +FQ L LE L ++ N + GI
Sbjct 135 SKN-HLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 193
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
F+ L LK F+ +R + L + L L L N+I+ I AF+ L LE
Sbjct 194 FSHLTKLK------EFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLE 247
Query 435 VLDLGLNEI 443
LD+ N++
Sbjct 248 RLDISNNQL 256
Score = 37.0 bits (84), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 54/202 (27%), Positives = 89/202 (44%), Gaps = 10/202 (5%)
Query 345 KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
++D+F K + L++++N+I I L+ L+ L L ++ S+ T+ E
Sbjct 67 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDN--SISTVGVEDGAFR 124
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN-IFEIYL 463
L +L L+KN +S + L L V D + ++ Q LE I + L
Sbjct 125 EAISLKLLFLSKNHLSSVPVGLPVDLQELRV-DENRIAVISDMAFQNLTSLERLIVDGNL 183
Query 464 SYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIND 523
NK + +F+ + L+ + R +L S P P P +L L L +N I +I
Sbjct 184 LTNK--GIAEGTFSHLTKLKEFSIVRNSL----SHPPPDLPGTHLIRLYLQDNQINHIPL 237
Query 524 DMLEGLEKLEILDLQHNNLARL 545
L KLE LD+ +N L L
Sbjct 238 TAFANLRKLERLDISNNQLRML 259
Score = 36.6 bits (83), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 59/142 (42%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ VP LP ++ L + N++ + F + L L V N ++ + L
Sbjct 139 LSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLT 198
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
LK ++ N LS T+L L+L N I I F + L LD+S+N L
Sbjct 199 KLKEFSIVRNSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQL 256
Query 160 SSTKLGTQVQLENLQELLLSNN 181
G L NL++L NN
Sbjct 257 RMLTQGVFDHLSNLKQLTARNN 278
>5ftu_B B LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2
Length=339
Score = 64.7 bits (156), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 81/282 (29%), Positives = 129/282 (46%), Gaps = 26/282 (9%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C C+ LT VP +P +TVL L +NQ+ A + S+ +
Sbjct 8 CRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINN--AGFPAELHNVQSVHTVYLYG 65
Query 88 SKLEPELCQKLPM-LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPFV 144
++L+ E LP ++VL+LQ N + +S A L ELHL NSI +++ F
Sbjct 66 NQLD-EFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFR 124
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLE 203
+ +L L LS N LSS +G V +LQEL + N+I + F N +SL++L
Sbjct 125 EAISLKLLFLSKNHLSSVPVGLPV---DLQELRVDENRIAVISDMA---FQNLTSLERLI 178
Query 204 LSSNQI--KEFSPGCFHAIGRL--FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
+ N + K + G F + +L F + N++ P +L T + L L ++Q
Sbjct 179 VDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPP-------DLPGTHLIRLYLQDNQ 231
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
++ T F L+ L LD+S N L ++ F L L+
Sbjct 232 INHIPLTAFANLR--KLERLDISNNQLRMLTQGVFDHLSNLK 271
Score = 53.9 bits (128), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 78/290 (27%), Positives = 118/290 (41%), Gaps = 58/290 (20%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
+ +L+L +N I I A + L LE L L N I G E + F +S K
Sbjct 79 VRVLHLQENNIQTISRAALAQLLKLEELHLDDNSIST--VGVE----DGAFREAISL-KL 131
Query 469 LQLTRNSFALVP-----SLQRLML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN- 520
L L++N + VP LQ L + R+A+ S FQ L +L L + N + N
Sbjct 132 LFLSKNHLSSVPVGLPVDLQELRVDENRIAV----ISDMAFQNLTSLERLIVDGNLLTNK 187
Query 521 -INDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I + L KL+ + N+L+ H P P +HL L L+ N + IP+
Sbjct 188 GIAEGTFSHLTKLKEFSIVRNSLS----HPPPDLPG------THLIRLYLQDNQINHIPL 237
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F +L +L+ +D+ N L L VF++ NL +
Sbjct 238 TAFANLRKLERLDISNNQLRMLTQGVFDH-------------------------LSNLKQ 272
Query 640 LDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
L R NP+ C C SI W W+ +++ ++C P G VR
Sbjct 273 LTARNNPWFCDC-SIKWVTEWLKYIPSSLN--VRGFMCQGPEQVRGMAVR 319
Score = 41.6 bits (96), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 57/217 (26%), Positives = 95/217 (44%), Gaps = 33/217 (15%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKL 98
+L + P +LP N+ VL+L N ++ + A + +L L + N+IS +E ++
Sbjct 67 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREA 126
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
LK+L L N LS + +L EL + N I I + F +L L + N
Sbjct 127 ISLKLLFLSKNHLSSVP---VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNL 183
Query 159 LSSTKL--GTQVQLENLQE----------------------LLLSNNKIQALKSEELDIF 194
L++ + GT L L+E L L +N+I + L F
Sbjct 184 LTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIP---LTAF 240
Query 195 AN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AN L++L++S+NQ++ + G F + L L N
Sbjct 241 ANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARN 277
Score = 41.2 bits (95), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 42/140 (30%), Positives = 67/140 (48%), Gaps = 11/140 (8%)
Query 501 PFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG 560
P +N+ +L L NNI I+ L L KLE L L N+++ + F +
Sbjct 72 PMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDG-----AFREA 126
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
+S L +L L N +PV + DL EL++ + N + + F N SL+ L + N
Sbjct 127 IS-LKLLFLSKNHLSSVPVGLPVDLQELRVDE---NRIAVISDMAFQNLTSLERLIVDGN 182
Query 621 LITSVEKKVFGPAFRNLTEL 640
L+T+ K + F +LT+L
Sbjct 183 LLTN--KGIAEGTFSHLTKL 200
Score = 37.0 bits (84), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 52/189 (28%), Positives = 82/189 (43%), Gaps = 30/189 (16%)
Query 275 NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
N+ +L L NN+ + + A L +LE L+ N+I + G F ++LK F
Sbjct 78 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVED--GAFR-EAISLKLLFL 134
Query 335 KQSISLASLP------------------KIDDFSFQWLKCLEHLNMEDNDI--PGIKSNM 374
++ L+S+P I D +FQ L LE L ++ N + GI
Sbjct 135 SKN-HLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 193
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
F+ L LK F+ +R + L + L L L N+I+ I AF+ L LE
Sbjct 194 FSHLTKLK------EFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLE 247
Query 435 VLDLGLNEI 443
LD+ N++
Sbjct 248 RLDISNNQL 256
Score = 37.0 bits (84), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 54/202 (27%), Positives = 89/202 (44%), Gaps = 10/202 (5%)
Query 345 KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
++D+F K + L++++N+I I L+ L+ L L ++ S+ T+ E
Sbjct 67 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDN--SISTVGVEDGAFR 124
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN-IFEIYL 463
L +L L+KN +S + L L V D + ++ Q LE I + L
Sbjct 125 EAISLKLLFLSKNHLSSVPVGLPVDLQELRV-DENRIAVISDMAFQNLTSLERLIVDGNL 183
Query 464 SYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIND 523
NK + +F+ + L+ + R +L S P P P +L L L +N I +I
Sbjct 184 LTNK--GIAEGTFSHLTKLKEFSIVRNSL----SHPPPDLPGTHLIRLYLQDNQINHIPL 237
Query 524 DMLEGLEKLEILDLQHNNLARL 545
L KLE LD+ +N L L
Sbjct 238 TAFANLRKLERLDISNNQLRML 259
Score = 36.6 bits (83), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 59/142 (42%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ VP LP ++ L + N++ + F + L L V N ++ + L
Sbjct 139 LSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLT 198
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
LK ++ N LS T+L L+L N I I F + L LD+S+N L
Sbjct 199 KLKEFSIVRNSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQL 256
Query 160 SSTKLGTQVQLENLQELLLSNN 181
G L NL++L NN
Sbjct 257 RMLTQGVFDHLSNLKQLTARNN 278
>2o6r_A A Variable lymphocyte receptor B
Length=177
Score = 62.0 bits (149), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 39/118 (33%), Positives = 60/118 (51%), Gaps = 0/118 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S C+ LT VP +P++ T L L N+L+ LP F + +QLT L + N
Sbjct 3 SRCSCSGTEIRCNSKGLTSVPTGIPSSATRLELESNKLQSLPHGVFDKLTQLTKLSLSQN 62
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
I L + KL L +L L N+L L + F T L EL L +N ++ + + F
Sbjct 63 QIQSLPDGVFDKLTKLTILYLHENKLQSLPNGVFDKLTQLKELALDTNQLKSVPDGIF 120
Score = 60.5 bits (145), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 41/129 (32%), Positives = 61/129 (47%), Gaps = 9/129 (7%)
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L+L+ N L L P L+ L L+L N +P VF L +L I+ L
Sbjct 33 LELESNKLQSL--------PHGVFDKLTQLTKLSLSQNQIQSLPDGVFDKLTKLTILYLH 84
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
N L +LP VF+ LK L L N + SV +F +L ++ + NP+DC+C I
Sbjct 85 ENKLQSLPNGVFDKLTQLKELALDTNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRI 143
Query 655 AWFVNWINE 663
+ W+N+
Sbjct 144 DYLSRWLNK 152
Score = 43.1 bits (100), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 35/106 (33%), Positives = 52/106 (49%), Gaps = 2/106 (2%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
++ T L L SN +Q + + F K L L LS N + S G +L L L L NK
Sbjct 28 SSATRLELESNKLQSLPHGVFDKLTQLTKLSLSQNQIQSLPDGVFDKLTKLTILYLHENK 87
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+Q+L + D + LK+L L +NQ+K G F + L ++L
Sbjct 88 LQSLPNGVFDKL--TQLKELALDTNQLKSVPDGIFDRLTSLQKIWL 131
>6s6q_B B LRR receptor-like serine/threonine-protein kinase GSO1
Length=863
Score = 66.2 bits (160), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 159/601 (26%), Positives = 242/601 (40%), Gaps = 85/601 (14%)
Query 58 LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDK 117
L N L A S LT N ++ P +L L++LNL +N L+
Sbjct 185 LQDNYLEGPIPAELGNCSDLTVFTAAENMLNGTIPAELGRLENLEILNLANNSLTGEIPS 244
Query 118 TFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELL 177
+ L L LM+N +Q + NL TLDLS N L+ + L +L+
Sbjct 245 QLGEMSQLQYLSLMANQLQGLIPKSLADLGNLQTLDLSANNLTGEIPEEFWNMSQLLDLV 304
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSL 237
L+NN + + + N++L++L LS Q+ P L L L+N L S+
Sbjct 305 LANNHLSGSLPKSI-CSNNTNLEQLVLSGTQLSGEIPVELSKCQSLKQLDLSNNSLAGSI 363
Query 238 TEKL--CLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
E L +EL + + N +L + + SN TNL L L +NNL +
Sbjct 364 PEALFELVELTDLYLHNNTLEGTLSPSISN-------LTNLQWLVLYHNNLEGKLPKEIS 416
Query 296 WLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLK 355
L +LE FL N + +++ +++ + + I P I LK
Sbjct 417 ALRKLEVLFLYENRFSGEIPQEIGNCTSLKMIDMFGNHFEGEIP----PSIGR-----LK 467
Query 356 CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLT 415
L L++ N++ G GL SL N L+IL+L
Sbjct 468 ELNLLHLRQNELVG-------GL----PASLGNCHQ-----------------LNILDLA 499
Query 416 KNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNK-------- 467
N++S +F +L LE L L N + L L N+ I LS+N+
Sbjct 500 DNQLSGSIPSSFGFLKGLEQLMLYNNSLQGNLP-DSLISLRNLTRINLSHNRLNGTIHPL 558
Query 468 -----YL--QLTRNSFA-LVP-------SLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
YL +T N F +P +L RL L + L P +R L++LD
Sbjct 559 CGSSSYLSFDVTNNGFEDEIPLELGNSQNLDRLRLGKNQL--TGKIPWTLGKIRELSLLD 616
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPI-YFLKGLSHLHILNLES 571
+S+N + L +KL +DL +N L+ GPI +L LS L L L S
Sbjct 617 MSSNALTGTIPLQLVLCKKLTHIDLNNNFLS---------GPIPPWLGKLSQLGELKLSS 667
Query 572 NGFDE-IPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N F E +P E+F + +L ++ L N+LN N +L LNL KN + +
Sbjct 668 NQFVESLPTELF-NCTKLLVLSLDGNSLNGSIPQEIGNLGALNVLNLDKNQFSGSLPQAM 726
Query 631 G 631
G
Sbjct 727 G 727
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 100/389 (26%), Positives = 159/389 (41%), Gaps = 85/389 (22%)
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKR 331
++ NL LDLS NNL + + L LE FL N + L L N+R L +
Sbjct 80 RFDNLIHLDLSSNNLVGPIPTALSNLTSLESLFLFSNQLTGEIPSQLGSLVNIRSLRIGD 139
Query 332 S-------------FTKQSISLASLPKIDDFSFQW--LKCLEHLNMEDNDIPG------- 369
+ Q ++LAS Q L ++ L ++DN + G
Sbjct 140 NELVGDIPETLGNLVNLQMLALASCRLTGPIPSQLGRLVRVQSLILQDNYLEGPIPAELG 199
Query 370 ---------IKSNMFTGLI--------NLKYLSLSNSFTSLRTLTNETFVSLAH-SPLHI 411
NM G I NL+ L+L+N+ +LT E L S L
Sbjct 200 NCSDLTVFTAAENMLNGTIPAELGRLENLEILNLANN-----SLTGEIPSQLGEMSQLQY 254
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL-Q 470
L+L N++ + + + LG+L+ LDL N + E+ + W + + ++ L+ N
Sbjct 255 LSLMANQLQGLIPKSLADLGNLQTLDLSANNLTGEIPEEFWN-MSQLLDLVLANNHLSGS 313
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN---------- 520
L ++ + +L++L+L L P ++L LDLSNN++A
Sbjct 314 LPKSICSNNTNLEQLVLSGTQLSG--EIPVELSKCQSLKQLDLSNNSLAGSIPEALFELV 371
Query 521 ------INDDMLEG--------LEKLEILDLQHNNL-ARLWKHANPGGPIYFLKGLSHLH 565
++++ LEG L L+ L L HNNL +L K + L L
Sbjct 372 ELTDLYLHNNTLEGTLSPSISNLTNLQWLVLYHNNLEGKLPKE---------ISALRKLE 422
Query 566 ILNLESNGF-DEIPVEVFKDLFELKIIDL 593
+L L N F EIP E+ + LK+ID+
Sbjct 423 VLFLYENRFSGEIPQEI-GNCTSLKMIDM 450
Score = 42.0 bits (97), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 145/632 (23%), Positives = 234/632 (37%), Gaps = 127/632 (20%)
Query 30 VSHEVADCSHLKL---------TQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLT 78
+ E+ +CS L + +P +L N+ +LNL +N L + SQL
Sbjct 194 IPAELGNCSDLTVFTAAENMLNGTIPAELGRLENLEILNLANNSLTGEIPSQLGEMSQLQ 253
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL-----------SQLSDKTFA------- 120
L + N + L P+ L L+ L+L N L SQL D A
Sbjct 254 YLSLMANQLQGLIPKSLADLGNLQTLDLSANNLTGEIPEEFWNMSQLLDLVLANNHLSGS 313
Query 121 ----FCTNLTELHLMSNSIQKIKNNPFV---KQKNLITLDLSHNGLSSTKLGTQVQLENL 173
C+N T L + S ++ V K ++L LDLS+N L+ + +L L
Sbjct 314 LPKSICSNNTNLEQLVLSGTQLSGEIPVELSKCQSLKQLDLSNNSLAGSIPEALFELVEL 373
Query 174 QELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
+L L NN ++ S + N L+ L L N ++ P A+ +L LFL +
Sbjct 374 TDLYLHNNTLEGTLSPSISNLTN--LQWLVLYHNNLEGKLPKEISALRKLEVLFLYENRF 431
Query 234 GPSLTEKLCLELAN-TSIRNLSLSNSQLSTTSNTTFLGLKWTNL---------------- 276
+ + E+ N TS++ + + + + LK NL
Sbjct 432 SGEIPQ----EIGNCTSLKMIDMFGNHFEGEIPPSIGRLKELNLLHLRQNELVGGLPASL 487
Query 277 ------TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
+LDL+ N L+ SF +L LE L N++Q SL L N+ +NL
Sbjct 488 GNCHQLNILDLADNQLSGSIPSSFGFLKGLEQLMLYNNSLQGNLPDSLISLRNLTRINLS 547
Query 331 RSFTKQSI----SLASLPKID----------DFSFQWLKCLEHLNMEDNDIPG------- 369
+ +I +S D + L+ L + N + G
Sbjct 548 HNRLNGTIHPLCGSSSYLSFDVTNNGFEDEIPLELGNSQNLDRLRLGKNQLTGKIPWTLG 607
Query 370 ---------IKSNMFTGLINLK--------YLSLSNSFTS---------------LRTLT 397
+ SN TG I L+ ++ L+N+F S L+ +
Sbjct 608 KIRELSLLDMSSNALTGTIPLQLVLCKKLTHIDLNNNFLSGPIPPWLGKLSQLGELKLSS 667
Query 398 NETFVSLAH-----SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
N+ SL + L +L+L N ++ LG L VL+L N+ L Q
Sbjct 668 NQFVESLPTELFNCTKLLVLSLDGNSLNGSIPQEIGNLGALNVLNLDKNQFSGSLP-QAM 726
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS-PSPFQPLRNLTIL 511
L ++E+ LS N + LQ + ++ N PS L L L
Sbjct 727 GKLSKLYELRLSRNSLTGEIPVEIGQLQDLQSAL--DLSYNNFTGDIPSTIGTLSKLETL 784
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
DLS+N + + ++ L L++ NNL
Sbjct 785 DLSHNQLTGEVPGSVGDMKSLGYLNVSFNNLG 816
>6s6q_A A LRR receptor-like serine/threonine-protein kinase GSO1
Length=863
Score = 66.2 bits (160), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 159/601 (26%), Positives = 242/601 (40%), Gaps = 85/601 (14%)
Query 58 LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDK 117
L N L A S LT N ++ P +L L++LNL +N L+
Sbjct 185 LQDNYLEGPIPAELGNCSDLTVFTAAENMLNGTIPAELGRLENLEILNLANNSLTGEIPS 244
Query 118 TFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELL 177
+ L L LM+N +Q + NL TLDLS N L+ + L +L+
Sbjct 245 QLGEMSQLQYLSLMANQLQGLIPKSLADLGNLQTLDLSANNLTGEIPEEFWNMSQLLDLV 304
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSL 237
L+NN + + + N++L++L LS Q+ P L L L+N L S+
Sbjct 305 LANNHLSGSLPKSI-CSNNTNLEQLVLSGTQLSGEIPVELSKCQSLKQLDLSNNSLAGSI 363
Query 238 TEKL--CLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
E L +EL + + N +L + + SN TNL L L +NNL +
Sbjct 364 PEALFELVELTDLYLHNNTLEGTLSPSISN-------LTNLQWLVLYHNNLEGKLPKEIS 416
Query 296 WLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLK 355
L +LE FL N + +++ +++ + + I P I LK
Sbjct 417 ALRKLEVLFLYENRFSGEIPQEIGNCTSLKMIDMFGNHFEGEIP----PSIGR-----LK 467
Query 356 CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLT 415
L L++ N++ G GL SL N L+IL+L
Sbjct 468 ELNLLHLRQNELVG-------GL----PASLGNCHQ-----------------LNILDLA 499
Query 416 KNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNK-------- 467
N++S +F +L LE L L N + L L N+ I LS+N+
Sbjct 500 DNQLSGSIPSSFGFLKGLEQLMLYNNSLQGNLP-DSLISLRNLTRINLSHNRLNGTIHPL 558
Query 468 -----YL--QLTRNSFA-LVP-------SLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
YL +T N F +P +L RL L + L P +R L++LD
Sbjct 559 CGSSSYLSFDVTNNGFEDEIPLELGNSQNLDRLRLGKNQL--TGKIPWTLGKIRELSLLD 616
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPI-YFLKGLSHLHILNLES 571
+S+N + L +KL +DL +N L+ GPI +L LS L L L S
Sbjct 617 MSSNALTGTIPLQLVLCKKLTHIDLNNNFLS---------GPIPPWLGKLSQLGELKLSS 667
Query 572 NGFDE-IPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N F E +P E+F + +L ++ L N+LN N +L LNL KN + +
Sbjct 668 NQFVESLPTELF-NCTKLLVLSLDGNSLNGSIPQEIGNLGALNVLNLDKNQFSGSLPQAM 726
Query 631 G 631
G
Sbjct 727 G 727
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 100/389 (26%), Positives = 159/389 (41%), Gaps = 85/389 (22%)
Query 272 KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKR 331
++ NL LDLS NNL + + L LE FL N + L L N+R L +
Sbjct 80 RFDNLIHLDLSSNNLVGPIPTALSNLTSLESLFLFSNQLTGEIPSQLGSLVNIRSLRIGD 139
Query 332 S-------------FTKQSISLASLPKIDDFSFQW--LKCLEHLNMEDNDIPG------- 369
+ Q ++LAS Q L ++ L ++DN + G
Sbjct 140 NELVGDIPETLGNLVNLQMLALASCRLTGPIPSQLGRLVRVQSLILQDNYLEGPIPAELG 199
Query 370 ---------IKSNMFTGLI--------NLKYLSLSNSFTSLRTLTNETFVSLAH-SPLHI 411
NM G I NL+ L+L+N+ +LT E L S L
Sbjct 200 NCSDLTVFTAAENMLNGTIPAELGRLENLEILNLANN-----SLTGEIPSQLGEMSQLQY 254
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL-Q 470
L+L N++ + + + LG+L+ LDL N + E+ + W + + ++ L+ N
Sbjct 255 LSLMANQLQGLIPKSLADLGNLQTLDLSANNLTGEIPEEFWN-MSQLLDLVLANNHLSGS 313
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN---------- 520
L ++ + +L++L+L L P ++L LDLSNN++A
Sbjct 314 LPKSICSNNTNLEQLVLSGTQLSG--EIPVELSKCQSLKQLDLSNNSLAGSIPEALFELV 371
Query 521 ------INDDMLEG--------LEKLEILDLQHNNL-ARLWKHANPGGPIYFLKGLSHLH 565
++++ LEG L L+ L L HNNL +L K + L L
Sbjct 372 ELTDLYLHNNTLEGTLSPSISNLTNLQWLVLYHNNLEGKLPKE---------ISALRKLE 422
Query 566 ILNLESNGF-DEIPVEVFKDLFELKIIDL 593
+L L N F EIP E+ + LK+ID+
Sbjct 423 VLFLYENRFSGEIPQEI-GNCTSLKMIDM 450
Score = 42.0 bits (97), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 145/632 (23%), Positives = 234/632 (37%), Gaps = 127/632 (20%)
Query 30 VSHEVADCSHLKL---------TQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLT 78
+ E+ +CS L + +P +L N+ +LNL +N L + SQL
Sbjct 194 IPAELGNCSDLTVFTAAENMLNGTIPAELGRLENLEILNLANNSLTGEIPSQLGEMSQLQ 253
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL-----------SQLSDKTFA------- 120
L + N + L P+ L L+ L+L N L SQL D A
Sbjct 254 YLSLMANQLQGLIPKSLADLGNLQTLDLSANNLTGEIPEEFWNMSQLLDLVLANNHLSGS 313
Query 121 ----FCTNLTELHLMSNSIQKIKNNPFV---KQKNLITLDLSHNGLSSTKLGTQVQLENL 173
C+N T L + S ++ V K ++L LDLS+N L+ + +L L
Sbjct 314 LPKSICSNNTNLEQLVLSGTQLSGEIPVELSKCQSLKQLDLSNNSLAGSIPEALFELVEL 373
Query 174 QELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
+L L NN ++ S + N L+ L L N ++ P A+ +L LFL +
Sbjct 374 TDLYLHNNTLEGTLSPSISNLTN--LQWLVLYHNNLEGKLPKEISALRKLEVLFLYENRF 431
Query 234 GPSLTEKLCLELAN-TSIRNLSLSNSQLSTTSNTTFLGLKWTNL---------------- 276
+ + E+ N TS++ + + + + LK NL
Sbjct 432 SGEIPQ----EIGNCTSLKMIDMFGNHFEGEIPPSIGRLKELNLLHLRQNELVGGLPASL 487
Query 277 ------TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
+LDL+ N L+ SF +L LE L N++Q SL L N+ +NL
Sbjct 488 GNCHQLNILDLADNQLSGSIPSSFGFLKGLEQLMLYNNSLQGNLPDSLISLRNLTRINLS 547
Query 331 RSFTKQSI----SLASLPKID----------DFSFQWLKCLEHLNMEDNDIPG------- 369
+ +I +S D + L+ L + N + G
Sbjct 548 HNRLNGTIHPLCGSSSYLSFDVTNNGFEDEIPLELGNSQNLDRLRLGKNQLTGKIPWTLG 607
Query 370 ---------IKSNMFTGLINLK--------YLSLSNSFTS---------------LRTLT 397
+ SN TG I L+ ++ L+N+F S L+ +
Sbjct 608 KIRELSLLDMSSNALTGTIPLQLVLCKKLTHIDLNNNFLSGPIPPWLGKLSQLGELKLSS 667
Query 398 NETFVSLAH-----SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
N+ SL + L +L+L N ++ LG L VL+L N+ L Q
Sbjct 668 NQFVESLPTELFNCTKLLVLSLDGNSLNGSIPQEIGNLGALNVLNLDKNQFSGSLP-QAM 726
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS-PSPFQPLRNLTIL 511
L ++E+ LS N + LQ + ++ N PS L L L
Sbjct 727 GKLSKLYELRLSRNSLTGEIPVEIGQLQDLQSAL--DLSYNNFTGDIPSTIGTLSKLETL 784
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
DLS+N + + ++ L L++ NNL
Sbjct 785 DLSHNQLTGEVPGSVGDMKSLGYLNVSFNNLG 816
>5ftt_F F LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2
Length=339
Score = 64.7 bits (156), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 81/282 (29%), Positives = 129/282 (46%), Gaps = 26/282 (9%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C C+ LT VP +P +TVL L +NQ+ A + S+ +
Sbjct 8 CRCDRNFVYCNERSLTSVPLGIPEGVTVLYLHNNQINN--AGFPAELHNVQSVHTVYLYG 65
Query 88 SKLEPELCQKLPM-LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPFV 144
++L+ E LP ++VL+LQ N + +S A L ELHL NSI +++ F
Sbjct 66 NQLD-EFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFR 124
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLE 203
+ +L L LS N LSS +G V +LQEL + N+I + F N +SL++L
Sbjct 125 EAISLKLLFLSKNHLSSVPVGLPV---DLQELRVDENRIAVISDMA---FQNLTSLERLI 178
Query 204 LSSNQI--KEFSPGCFHAIGRL--FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
+ N + K + G F + +L F + N++ P +L T + L L ++Q
Sbjct 179 VDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPP-------DLPGTHLIRLYLQDNQ 231
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
++ T F L+ L LD+S N L ++ F L L+
Sbjct 232 INHIPLTAFANLR--KLERLDISNNQLRMLTQGVFDHLSNLK 271
Score = 53.9 bits (128), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 78/290 (27%), Positives = 118/290 (41%), Gaps = 58/290 (20%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
+ +L+L +N I I A + L LE L L N I G E + F +S K
Sbjct 79 VRVLHLQENNIQTISRAALAQLLKLEELHLDDNSIST--VGVE----DGAFREAISL-KL 131
Query 469 LQLTRNSFALVP-----SLQRLML--RRVALKNVDSSPSPFQPLRNLTILDLSNNNIAN- 520
L L++N + VP LQ L + R+A+ S FQ L +L L + N + N
Sbjct 132 LFLSKNHLSSVPVGLPVDLQELRVDENRIAV----ISDMAFQNLTSLERLIVDGNLLTNK 187
Query 521 -INDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I + L KL+ + N+L+ H P P +HL L L+ N + IP+
Sbjct 188 GIAEGTFSHLTKLKEFSIVRNSLS----HPPPDLPG------THLIRLYLQDNQINHIPL 237
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F +L +L+ +D+ N L L VF++ NL +
Sbjct 238 TAFANLRKLERLDISNNQLRMLTQGVFDH-------------------------LSNLKQ 272
Query 640 LDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR 689
L R NP+ C C SI W W+ +++ ++C P G VR
Sbjct 273 LTARNNPWFCDC-SIKWVTEWLKYIPSSLN--VRGFMCQGPEQVRGMAVR 319
Score = 41.6 bits (96), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 57/217 (26%), Positives = 95/217 (44%), Gaps = 33/217 (15%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKL 98
+L + P +LP N+ VL+L N ++ + A + +L L + N+IS +E ++
Sbjct 67 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDGAFREA 126
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
LK+L L N LS + +L EL + N I I + F +L L + N
Sbjct 127 ISLKLLFLSKNHLSSVP---VGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNL 183
Query 159 LSSTKL--GTQVQLENLQE----------------------LLLSNNKIQALKSEELDIF 194
L++ + GT L L+E L L +N+I + L F
Sbjct 184 LTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIP---LTAF 240
Query 195 AN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AN L++L++S+NQ++ + G F + L L N
Sbjct 241 ANLRKLERLDISNNQLRMLTQGVFDHLSNLKQLTARN 277
Score = 41.2 bits (95), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 42/140 (30%), Positives = 67/140 (48%), Gaps = 11/140 (8%)
Query 501 PFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG 560
P +N+ +L L NNI I+ L L KLE L L N+++ + F +
Sbjct 72 PMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVEDG-----AFREA 126
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
+S L +L L N +PV + DL EL++ + N + + F N SL+ L + N
Sbjct 127 IS-LKLLFLSKNHLSSVPVGLPVDLQELRVDE---NRIAVISDMAFQNLTSLERLIVDGN 182
Query 621 LITSVEKKVFGPAFRNLTEL 640
L+T+ K + F +LT+L
Sbjct 183 LLTN--KGIAEGTFSHLTKL 200
Score = 37.0 bits (84), Expect = 0.80, Method: Compositional matrix adjust.
Identities = 54/202 (27%), Positives = 89/202 (44%), Gaps = 10/202 (5%)
Query 345 KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
++D+F K + L++++N+I I L+ L+ L L ++ S+ T+ E
Sbjct 67 QLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDN--SISTVGVEDGAFR 124
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN-IFEIYL 463
L +L L+KN +S + L L V D + ++ Q LE I + L
Sbjct 125 EAISLKLLFLSKNHLSSVPVGLPVDLQELRV-DENRIAVISDMAFQNLTSLERLIVDGNL 183
Query 464 SYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIND 523
NK + +F+ + L+ + R +L S P P P +L L L +N I +I
Sbjct 184 LTNK--GIAEGTFSHLTKLKEFSIVRNSL----SHPPPDLPGTHLIRLYLQDNQINHIPL 237
Query 524 DMLEGLEKLEILDLQHNNLARL 545
L KLE LD+ +N L L
Sbjct 238 TAFANLRKLERLDISNNQLRML 259
Score = 37.0 bits (84), Expect = 0.91, Method: Compositional matrix adjust.
Identities = 52/189 (28%), Positives = 82/189 (43%), Gaps = 30/189 (16%)
Query 275 NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
N+ +L L NN+ + + A L +LE L+ N+I + G F ++LK F
Sbjct 78 NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVED--GAFR-EAISLKLLFL 134
Query 335 KQSISLASLP------------------KIDDFSFQWLKCLEHLNMEDNDI--PGIKSNM 374
++ L+S+P I D +FQ L LE L ++ N + GI
Sbjct 135 SKN-HLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGT 193
Query 375 FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLE 434
F+ L LK F+ +R + L + L L L N+I+ I AF+ L LE
Sbjct 194 FSHLTKLK------EFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFANLRKLE 247
Query 435 VLDLGLNEI 443
LD+ N++
Sbjct 248 RLDISNNQL 256
Score = 36.6 bits (83), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 39/142 (27%), Positives = 59/142 (42%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ VP LP ++ L + N++ + F + L L V N ++ + L
Sbjct 139 LSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLT 198
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
LK ++ N LS T+L L+L N I I F + L LD+S+N L
Sbjct 199 KLKEFSIVRNSLSHPPPDLPG--THLIRLYLQDNQINHIPLTAFANLRKLERLDISNNQL 256
Query 160 SSTKLGTQVQLENLQELLLSNN 181
G L NL++L NN
Sbjct 257 RMLTQGVFDHLSNLKQLTARNN 278
>7r54_A A Toll-like receptor 8
Length=807
Score = 65.9 bits (159), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 92/340 (27%), Positives = 149/340 (44%), Gaps = 28/340 (8%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L++ N I I N F L ++ L+LS + ++ + L+ F ++ H + L+LT N++
Sbjct 460 LDLSLNSIFFIGPNQFENLPDIACLNLSAN-SNAQVLSGTEFSAIPH--VKYLDLTNNRL 516
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTG-----QEWRGLENIFEIYLSYNKYLQLTRN 474
+ A + L LEVLDL N + G + + N+ + LS+N LT
Sbjct 517 DFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTXK 576
Query 475 SFALVPSLQRLMLRRVALK-----NVDSSPSPFQPLRNLTILDLSNNNIANI-NDDMLEG 528
SL L+ L + S F+ L+NLT LDLS N + +I N+ L
Sbjct 577 YNLESKSLVELVFSGNRLDILWNXXXNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNL 636
Query 529 LEKLEILDLQHNNLARL-WKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFE 587
L L + N L W L+ L +L+L N + +
Sbjct 637 PASLTELHINDNMLKFFNWT---------LLQQFPRLELLDLRGNKLLFLTDSLSDFTSS 687
Query 588 LKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF-GPAFRNLTELDMRFNP 646
L+ + L N ++ LP+ + SLK L+L NL+ ++ K L+ L++ NP
Sbjct 688 LRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNP 747
Query 647 FDCTCESIAWFVNWINE-THTNIPELSSHYLCNTPPHYHG 685
F+CTC+ I F W++E + IP L +C +P G
Sbjct 748 FECTCD-IGDFRRWMDEHLNVKIPRLVD-VICASPGDQRG 785
Score = 64.3 bits (155), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 169/747 (23%), Positives = 286/747 (38%), Gaps = 164/747 (22%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N P
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHN------PN 73
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
+ N ++D F NL EL L N + +I P ++L L
Sbjct 74 VXXXXXXXXXXXXGLN----ITDGAFLNLKNLRELLLEDNQLPQI---PSGLPESLTELS 126
Query 154 LSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
L N + + +L NL+ L L+ N E+ +I
Sbjct 127 LIQNNIYNITKEGISRLINLKNLYLAWNCYXXXXCEKTNI-------------------E 167
Query 214 PGCFHAIGR---LFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLG 270
G F + L F + + P L +S+R L LSN+Q+ S F G
Sbjct 168 DGVFETLTNLELLSLSFNSLSHVPPKLP---------SSLRKLFLSNTQIKYISEEDFKG 218
Query 271 LKWTNLTMLDLSYN------------------NLNVVGNDSFAW--LPQLEYFFLEYNNI 310
L NLT+LDLS N ++N+ D FA+ L QL Y L ++
Sbjct 219 L--INLTLLDLSGNCPRCFNAPFPCVPCDGGASINI---DRFAFQNLTQLRYLNLSSTSL 273
Query 311 QHLFSHSLHGLFNVRYLNLKRSFTKQSIS----LASLPKID--DFSFQWLKC--LEHLNM 362
+ + + + +++ L+L+ ++ I+ L LP+++ D SF ++K +H+N+
Sbjct 274 RKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINI 333
Query 363 EDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILNLTKNKISK 421
N F+ L++L+ L L + L + F L P L +NL N I +
Sbjct 334 SRN---------FSKLLSLRALHLRGYV--FQELREDDFQPLMQLPNLSTINLGINFIKQ 382
Query 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL----------------------ENIF 459
I+ F +LE++ L N I N +
Sbjct 383 IDFKLFQNFSNLEIIYLSENRISPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXDPHSNFY 442
Query 460 EIY--------LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS-------SPSPFQP 504
+Y K L L+ NS + Q L +A N+ + S + F
Sbjct 443 HFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSA 502
Query 505 LRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
+ ++ LDL+NN + N L L LE+LDL +N + ++ A + F++ ++L
Sbjct 503 IPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYN--SHYFRIAGVTHHLEFIQNFTNL 560
Query 565 HILNLESNGFDEIP-------------------------------VEVFKDLFELKIIDL 593
+LNL N + + +FK L L +DL
Sbjct 561 KVLNLSHNNIYTLTXKYNLESKSLVELVFSGNRLDILWNXXXNRYISIFKGLKNLTRLDL 620
Query 594 GLNNLNTLPASVF-NNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCE 652
LN L +P F N SL L++ N++ + F L LD+R N +
Sbjct 621 SLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQ-QFPRLELLDLRGNKLLFLTD 679
Query 653 SIAWFVNWINE---THTNIPELSSHYL 676
S++ F + + +H I L S +L
Sbjct 680 SLSDFTSSLRTLLLSHNRISHLPSGFL 706
Score = 43.1 bits (100), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 43/157 (27%), Positives = 72/157 (46%), Gaps = 25/157 (16%)
Query 52 NITVLNLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
N+T L+L+ N+L+ +P F + LT L + N + L Q+ P L++L+L+ N+
Sbjct 614 NLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNK 673
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L+D F ++L TL LSHN +S G ++
Sbjct 674 LLFLTDSLSDFTSSLR------------------------TLLLSHNRISHLPSGFLSEV 709
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+L+ L LS+N ++ + L+ + L LEL N
Sbjct 710 SSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 746
Score = 39.3 bits (90), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 70/270 (26%), Positives = 112/270 (41%), Gaps = 18/270 (7%)
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLMSNSIQK 137
+LD+ N+I + P + LP + LNL N +Q LS F+ ++ L L +N +
Sbjct 459 ALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDF 518
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE------NLQELLLSNNKIQALKSEEL 191
+ + +L LDLS+N G LE NL+ L LS+N I L +
Sbjct 519 DNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTXKY- 577
Query 192 DIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIR 251
+ SL +L S N++ + +F N +L SL + N +
Sbjct 578 -NLESKSLVELVFSGNRLDILWNXXXNRYISIFKGLKNLTRLDLSLNR--LKHIPNEAFL 634
Query 252 NLSLSNSQLSTTSNTTFLGLKWT------NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFL 305
NL S ++L N WT L +LDL N L + + + L L
Sbjct 635 NLPASLTELHINDNMLKF-FNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLL 693
Query 306 EYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
+N I HL S L + ++++L+L + K
Sbjct 694 SHNRISHLPSGFLSEVSSLKHLDLSSNLLK 723
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 74/268 (28%), Positives = 111/268 (41%), Gaps = 63/268 (24%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT----ISKLEP--ELCQKLPMLKVLNL 106
+ L+LT+N+L A+ T S L LD+ +N+ I+ + E Q LKVLNL
Sbjct 506 VKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNL 565
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKN-------NPFVKQKNLITLDLSHNGL 159
HN + L+ K +L EL N + + N + F KNL LDLS N L
Sbjct 566 SHNNIYTLTXKYNLESKSLVELVFSGNRLDILWNXXXNRYISIFKGLKNLTRLDLSLNRL 625
Query 160 SSTKLGTQVQL-ENLQELLLSNNKI---------QALKSEELDIFAN------------- 196
+ L +L EL +++N + Q + E LD+ N
Sbjct 626 KHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFT 685
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLS 256
SSL+ L LS N+I G FL+ V +S+++L LS
Sbjct 686 SSLRTLLLSHNRISHLPSG-----------FLSEV----------------SSLKHLDLS 718
Query 257 NSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
++ L T + + T L+ML+L N
Sbjct 719 SNLLKTINKSALETKTTTKLSMLELHGN 746
Score = 38.5 bits (88), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 52/168 (31%), Positives = 74/168 (44%), Gaps = 10/168 (6%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTS-------LDVGFNTISKLEPELCQKLPMLKV 103
TN+ VLNL+HN + L L LD+ +N + + L L
Sbjct 558 TNLKVLNLSHNNIYTLTXKYNLESKSLVELVFSGNRLDILWNXXXNRYISIFKGLKNLTR 617
Query 104 LNLQHNELSQLSDKTFA-FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSST 162
L+L N L + ++ F +LTELH+ N ++ + L LDL N L
Sbjct 618 LDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFL 677
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+L+ LLLS+N+I L S L SSLK L+LSSN +K
Sbjct 678 TDSLSDFTSSLRTLLLSHNRISHLPSGFLSEV--SSLKHLDLSSNLLK 723
>6f2o_A A Leucine-rich repeat and fibronectin type-III domain-containing
protein 5
Length=388
Score = 64.7 bits (156), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 80/186 (43%), Gaps = 35/186 (19%)
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
E+ L+ N + R FA + SL L L R + + +P F LRNL L L++N +
Sbjct 60 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFI--TPHAFADLRNLRALHLNSNRLT 117
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I +DM GL S+LH L L +N I
Sbjct 118 KITNDMFSGL--------------------------------SNLHHLILNNNQLTLISS 145
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F D+F L+ +DL NNL T+P VSL +L+L N+I ++ K F +T
Sbjct 146 TAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFS-HLHKMTR 204
Query 640 LDMRFN 645
LD+ N
Sbjct 205 LDVTSN 210
Score = 53.9 bits (128), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 2/178 (1%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C+ L VP ++ L L N + + +F + L L + NTIS + P
Sbjct 42 CAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFA 101
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L+L N L+++++ F+ +NL L L +N + I + F L LDLS+
Sbjct 102 DLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSY 161
Query 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
N L + ++ +L L L +N I + + +L+++SN++++ P
Sbjct 162 NNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHL--HKMTRLDVTSNKLQKLPP 217
Score = 48.5 bits (114), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 50/147 (34%), Positives = 78/147 (53%), Gaps = 13/147 (9%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L++N + +K ++ FAN +SL L LS N I +P F + L L LN+ +L
Sbjct 60 ELRLADNFVTNIKRKD---FANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRL 116
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
+T + L+N + +L L+N+QL+ S+T F + L LDLSYNNL + D+
Sbjct 117 T-KITNDMFSGLSN--LHHLILNNNQLTLISSTAFDDV--FALEELDLSYNNLETIPWDA 171
Query 294 FAWLPQLEYFFLEYNNIQHL----FSH 316
+ L L++N I ++ FSH
Sbjct 172 VEKMVSLHTLSLDHNMIDNIPKGTFSH 198
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/106 (26%), Positives = 56/106 (53%), Gaps = 3/106 (3%)
Query 41 KLTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
+LT++ +D+ + ++ L+ L +NQL + + F L LD+ +N + + + +K
Sbjct 115 RLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEK 174
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
+ L L+L HN + + TF+ +T L + SN +QK+ +P
Sbjct 175 MVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPL 220
Score = 35.0 bits (79), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 39/171 (23%), Positives = 71/171 (42%), Gaps = 35/171 (20%)
Query 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT 391
S ++S ++ I +F L+ L L++ N + I ++MF+GL NL +L L+N
Sbjct 81 SLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNN--- 137
Query 392 SLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
N+++ I S AF + LE LDL N L
Sbjct 138 -------------------------NQLTLISSTAFDDVFALEELDLSYN----NLETIP 168
Query 452 WRGLENIFEIY---LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP 499
W +E + ++ L +N + + +F+ + + RL + L+ + P
Sbjct 169 WDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDP 219
>5xwt_B B Leucine-rich repeat and fibronectin type-III domain-containing
protein 5
Length=367
Score = 64.7 bits (156), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 80/186 (43%), Gaps = 35/186 (19%)
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
E+ L+ N + R FA + SL L L R + + +P F LRNL L L++N +
Sbjct 38 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFI--TPHAFADLRNLRALHLNSNRLT 95
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I +DM GL S+LH L L +N I
Sbjct 96 KITNDMFSGL--------------------------------SNLHHLILNNNQLTLISS 123
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F D+F L+ +DL NNL T+P VSL +L+L N+I ++ K F +T
Sbjct 124 TAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFS-HLHKMTR 182
Query 640 LDMRFN 645
LD+ N
Sbjct 183 LDVTSN 188
Score = 53.5 bits (127), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 2/178 (1%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C+ L VP ++ L L N + + +F + L L + NTIS + P
Sbjct 20 CAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFA 79
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L+L N L+++++ F+ +NL L L +N + I + F L LDLS+
Sbjct 80 DLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSY 139
Query 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
N L + ++ +L L L +N I + + +L+++SN++++ P
Sbjct 140 NNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHL--HKMTRLDVTSNKLQKLPP 195
Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 52/152 (34%), Positives = 81/152 (53%), Gaps = 14/152 (9%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L++N + +K ++ FAN +SL L LS N I +P F + L L LN+ +L
Sbjct 38 ELRLADNFVTNIKRKD---FANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRL 94
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
+T + L+N + +L L+N+QL+ S+T F + L LDLSYNNL + D+
Sbjct 95 T-KITNDMFSGLSN--LHHLILNNNQLTLISSTAFDDV--FALEELDLSYNNLETIPWDA 149
Query 294 FAWLPQLEYFFLEYNNIQHL----FSHSLHGL 321
+ L L++N I ++ FSH LH +
Sbjct 150 VEKMVSLHTLSLDHNMIDNIPKGTFSH-LHKM 180
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/112 (25%), Positives = 59/112 (53%), Gaps = 3/112 (3%)
Query 41 KLTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
+LT++ +D+ + ++ L+ L +NQL + + F L LD+ +N + + + +K
Sbjct 93 RLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEK 152
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
+ L L+L HN + + TF+ +T L + SN +QK+ +P ++ +
Sbjct 153 MVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQV 204
Score = 34.7 bits (78), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 39/171 (23%), Positives = 71/171 (42%), Gaps = 35/171 (20%)
Query 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT 391
S ++S ++ I +F L+ L L++ N + I ++MF+GL NL +L L+N
Sbjct 59 SLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNN--- 115
Query 392 SLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
N+++ I S AF + LE LDL N L
Sbjct 116 -------------------------NQLTLISSTAFDDVFALEELDLSYN----NLETIP 146
Query 452 WRGLENIFEIY---LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP 499
W +E + ++ L +N + + +F+ + + RL + L+ + P
Sbjct 147 WDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDP 197
>5xwt_D D Leucine-rich repeat and fibronectin type-III domain-containing
protein 5
Length=367
Score = 64.7 bits (156), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 80/186 (43%), Gaps = 35/186 (19%)
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
E+ L+ N + R FA + SL L L R + + +P F LRNL L L++N +
Sbjct 38 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFI--TPHAFADLRNLRALHLNSNRLT 95
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I +DM GL S+LH L L +N I
Sbjct 96 KITNDMFSGL--------------------------------SNLHHLILNNNQLTLISS 123
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F D+F L+ +DL NNL T+P VSL +L+L N+I ++ K F +T
Sbjct 124 TAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFS-HLHKMTR 182
Query 640 LDMRFN 645
LD+ N
Sbjct 183 LDVTSN 188
Score = 53.1 bits (126), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 2/178 (1%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C+ L VP ++ L L N + + +F + L L + NTIS + P
Sbjct 20 CAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFA 79
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L+L N L+++++ F+ +NL L L +N + I + F L LDLS+
Sbjct 80 DLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSY 139
Query 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
N L + ++ +L L L +N I + + +L+++SN++++ P
Sbjct 140 NNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHL--HKMTRLDVTSNKLQKLPP 195
Score = 48.1 bits (113), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 52/152 (34%), Positives = 81/152 (53%), Gaps = 14/152 (9%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L++N + +K ++ FAN +SL L LS N I +P F + L L LN+ +L
Sbjct 38 ELRLADNFVTNIKRKD---FANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRL 94
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
+T + L+N + +L L+N+QL+ S+T F + L LDLSYNNL + D+
Sbjct 95 T-KITNDMFSGLSN--LHHLILNNNQLTLISSTAFDDV--FALEELDLSYNNLETIPWDA 149
Query 294 FAWLPQLEYFFLEYNNIQHL----FSHSLHGL 321
+ L L++N I ++ FSH LH +
Sbjct 150 VEKMVSLHTLSLDHNMIDNIPKGTFSH-LHKM 180
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/112 (25%), Positives = 59/112 (53%), Gaps = 3/112 (3%)
Query 41 KLTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
+LT++ +D+ + ++ L+ L +NQL + + F L LD+ +N + + + +K
Sbjct 93 RLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEK 152
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
+ L L+L HN + + TF+ +T L + SN +QK+ +P ++ +
Sbjct 153 MVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQV 204
Score = 34.7 bits (78), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 39/171 (23%), Positives = 71/171 (42%), Gaps = 35/171 (20%)
Query 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT 391
S ++S ++ I +F L+ L L++ N + I ++MF+GL NL +L L+N
Sbjct 59 SLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNN--- 115
Query 392 SLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
N+++ I S AF + LE LDL N L
Sbjct 116 -------------------------NQLTLISSTAFDDVFALEELDLSYN----NLETIP 146
Query 452 WRGLENIFEIY---LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP 499
W +E + ++ L +N + + +F+ + + RL + L+ + P
Sbjct 147 WDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDP 197
>4k5u_D D Variable lymphocyte receptor
Length=220
Score = 62.4 bits (150), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 45/159 (28%), Positives = 71/159 (45%), Gaps = 10/159 (6%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L L L N L L P L++L L L
Sbjct 34 VLYLNSNQITKLEPGVFDRLANLRELHLWGNQLVSL--------PPGVFDNLANLEKLWL 85
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN +P +F L L+ + L L LP+ F+ LK L L +N + S+
Sbjct 86 NSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGAFDKLTRLKQLGLDQNQLKSIPDGA 145
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
F +LT + + NP+DC C I + W+ + H++I
Sbjct 146 FA-RLPSLTHVWLHTNPWDCQCTDILYLSGWVAQ-HSSI 182
Score = 60.1 bits (144), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/159 (29%), Positives = 69/159 (43%), Gaps = 0/159 (0%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDV 82
+ ++C+ S +C+ L VP +PT VL L NQ+ +L F R + L L +
Sbjct 2 ACPSQCSCSGTEVNCAGKSLASVPAGIPTTTRVLYLNSNQITKLEPGVFDRLANLRELHL 61
Query 83 GFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP 142
N + L P + L L+ L L N+L+ L F NL L L + ++ +
Sbjct 62 WGNQLVSLPPGVFDNLANLEKLWLNSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGA 121
Query 143 FVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
F K L L L N L S G +L +L + L N
Sbjct 122 FDKLTRLKQLGLDQNQLKSIPDGAFARLPSLTHVWLHTN 160
Score = 47.0 bits (110), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 45/133 (34%), Positives = 65/133 (49%), Gaps = 7/133 (5%)
Query 176 LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGP 235
L L++N+I L+ D AN L++L L NQ+ PG F + L L+LN+ QL
Sbjct 35 LYLNSNQITKLEPGVFDRLAN--LRELHLWGNQLVSLPPGVFDNLANLEKLWLNSNQLT- 91
Query 236 SLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
SL L L N + +L L +L+ + F L T L L L N L + + +FA
Sbjct 92 SLPAGLFDRLVN--LEHLGLCCMKLTELPSGAFDKL--TRLKQLGLDQNQLKSIPDGAFA 147
Query 296 WLPQLEYFFLEYN 308
LP L + +L N
Sbjct 148 RLPSLTHVWLHTN 160
Score = 35.4 bits (80), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 38/142 (27%), Positives = 61/142 (43%), Gaps = 13/142 (9%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L L N+I+K+E F L +L L L N++ L + L N+ +++L+ N+
Sbjct 33 RVLYLNSNQITKLEPGVFDRLANLRELHLWGNQL-VSLPPGVFDNLANLEKLWLNSNQLT 91
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L F + +L+ L L + L + S F L L L L N + +I D L
Sbjct 92 SLPAGLFDRLVNLEHLGLCCMKLTELPS--GAFDKLTRLKQLGLDQNQLKSIPDGAFARL 149
Query 530 EKLEILDLQHNNLARLWKHANP 551
+L +W H NP
Sbjct 150 P----------SLTHVWLHTNP 161
>4k5u_C C Variable lymphocyte receptor
Length=220
Score = 62.4 bits (150), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 45/159 (28%), Positives = 71/159 (45%), Gaps = 10/159 (6%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L L L N L L P L++L L L
Sbjct 34 VLYLNSNQITKLEPGVFDRLANLRELHLWGNQLVSL--------PPGVFDNLANLEKLWL 85
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN +P +F L L+ + L L LP+ F+ LK L L +N + S+
Sbjct 86 NSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGAFDKLTRLKQLGLDQNQLKSIPDGA 145
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
F +LT + + NP+DC C I + W+ + H++I
Sbjct 146 FA-RLPSLTHVWLHTNPWDCQCTDILYLSGWVAQ-HSSI 182
Score = 60.1 bits (144), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/159 (29%), Positives = 69/159 (43%), Gaps = 0/159 (0%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDV 82
+ ++C+ S +C+ L VP +PT VL L NQ+ +L F R + L L +
Sbjct 2 ACPSQCSCSGTEVNCAGKSLASVPAGIPTTTRVLYLNSNQITKLEPGVFDRLANLRELHL 61
Query 83 GFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP 142
N + L P + L L+ L L N+L+ L F NL L L + ++ +
Sbjct 62 WGNQLVSLPPGVFDNLANLEKLWLNSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGA 121
Query 143 FVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
F K L L L N L S G +L +L + L N
Sbjct 122 FDKLTRLKQLGLDQNQLKSIPDGAFARLPSLTHVWLHTN 160
Score = 47.0 bits (110), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 45/133 (34%), Positives = 65/133 (49%), Gaps = 7/133 (5%)
Query 176 LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGP 235
L L++N+I L+ D AN L++L L NQ+ PG F + L L+LN+ QL
Sbjct 35 LYLNSNQITKLEPGVFDRLAN--LRELHLWGNQLVSLPPGVFDNLANLEKLWLNSNQLT- 91
Query 236 SLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
SL L L N + +L L +L+ + F L T L L L N L + + +FA
Sbjct 92 SLPAGLFDRLVN--LEHLGLCCMKLTELPSGAFDKL--TRLKQLGLDQNQLKSIPDGAFA 147
Query 296 WLPQLEYFFLEYN 308
LP L + +L N
Sbjct 148 RLPSLTHVWLHTN 160
Score = 35.4 bits (80), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 38/142 (27%), Positives = 61/142 (43%), Gaps = 13/142 (9%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L L N+I+K+E F L +L L L N++ L + L N+ +++L+ N+
Sbjct 33 RVLYLNSNQITKLEPGVFDRLANLRELHLWGNQL-VSLPPGVFDNLANLEKLWLNSNQLT 91
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L F + +L+ L L + L + S F L L L L N + +I D L
Sbjct 92 SLPAGLFDRLVNLEHLGLCCMKLTELPS--GAFDKLTRLKQLGLDQNQLKSIPDGAFARL 149
Query 530 EKLEILDLQHNNLARLWKHANP 551
+L +W H NP
Sbjct 150 P----------SLTHVWLHTNP 161
>4k79_A A Variable lymphocyte receptor
Length=220
Score = 62.4 bits (150), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 45/159 (28%), Positives = 71/159 (45%), Gaps = 10/159 (6%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L L L N L L P L++L L L
Sbjct 34 VLYLNSNQITKLEPGVFDRLANLRELHLWGNQLVSL--------PPGVFDNLANLEKLWL 85
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN +P +F L L+ + L L LP+ F+ LK L L +N + S+
Sbjct 86 NSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGAFDKLTRLKQLGLDQNQLKSIPDGA 145
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
F +LT + + NP+DC C I + W+ + H++I
Sbjct 146 FA-RLPSLTHVWLHTNPWDCQCTDILYLSGWVAQ-HSSI 182
Score = 60.1 bits (144), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/159 (29%), Positives = 69/159 (43%), Gaps = 0/159 (0%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDV 82
+ ++C+ S +C+ L VP +PT VL L NQ+ +L F R + L L +
Sbjct 2 ACPSQCSCSGTEVNCAGKSLASVPAGIPTTTRVLYLNSNQITKLEPGVFDRLANLRELHL 61
Query 83 GFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP 142
N + L P + L L+ L L N+L+ L F NL L L + ++ +
Sbjct 62 WGNQLVSLPPGVFDNLANLEKLWLNSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGA 121
Query 143 FVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
F K L L L N L S G +L +L + L N
Sbjct 122 FDKLTRLKQLGLDQNQLKSIPDGAFARLPSLTHVWLHTN 160
Score = 47.4 bits (111), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 45/133 (34%), Positives = 65/133 (49%), Gaps = 7/133 (5%)
Query 176 LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGP 235
L L++N+I L+ D AN L++L L NQ+ PG F + L L+LN+ QL
Sbjct 35 LYLNSNQITKLEPGVFDRLAN--LRELHLWGNQLVSLPPGVFDNLANLEKLWLNSNQLT- 91
Query 236 SLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
SL L L N + +L L +L+ + F L T L L L N L + + +FA
Sbjct 92 SLPAGLFDRLVN--LEHLGLCCMKLTELPSGAFDKL--TRLKQLGLDQNQLKSIPDGAFA 147
Query 296 WLPQLEYFFLEYN 308
LP L + +L N
Sbjct 148 RLPSLTHVWLHTN 160
Score = 35.4 bits (80), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 38/142 (27%), Positives = 61/142 (43%), Gaps = 13/142 (9%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L L N+I+K+E F L +L L L N++ L + L N+ +++L+ N+
Sbjct 33 RVLYLNSNQITKLEPGVFDRLANLRELHLWGNQL-VSLPPGVFDNLANLEKLWLNSNQLT 91
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L F + +L+ L L + L + S F L L L L N + +I D L
Sbjct 92 SLPAGLFDRLVNLEHLGLCCMKLTELPS--GAFDKLTRLKQLGLDQNQLKSIPDGAFARL 149
Query 530 EKLEILDLQHNNLARLWKHANP 551
+L +W H NP
Sbjct 150 P----------SLTHVWLHTNP 161
>4k79_D D Variable lymphocyte receptor
Length=220
Score = 62.4 bits (150), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 45/159 (28%), Positives = 71/159 (45%), Gaps = 10/159 (6%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L L L N L L P L++L L L
Sbjct 34 VLYLNSNQITKLEPGVFDRLANLRELHLWGNQLVSL--------PPGVFDNLANLEKLWL 85
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN +P +F L L+ + L L LP+ F+ LK L L +N + S+
Sbjct 86 NSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGAFDKLTRLKQLGLDQNQLKSIPDGA 145
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
F +LT + + NP+DC C I + W+ + H++I
Sbjct 146 FA-RLPSLTHVWLHTNPWDCQCTDILYLSGWVAQ-HSSI 182
Score = 60.1 bits (144), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/159 (29%), Positives = 69/159 (43%), Gaps = 0/159 (0%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDV 82
+ ++C+ S +C+ L VP +PT VL L NQ+ +L F R + L L +
Sbjct 2 ACPSQCSCSGTEVNCAGKSLASVPAGIPTTTRVLYLNSNQITKLEPGVFDRLANLRELHL 61
Query 83 GFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP 142
N + L P + L L+ L L N+L+ L F NL L L + ++ +
Sbjct 62 WGNQLVSLPPGVFDNLANLEKLWLNSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGA 121
Query 143 FVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
F K L L L N L S G +L +L + L N
Sbjct 122 FDKLTRLKQLGLDQNQLKSIPDGAFARLPSLTHVWLHTN 160
Score = 47.4 bits (111), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 45/133 (34%), Positives = 65/133 (49%), Gaps = 7/133 (5%)
Query 176 LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGP 235
L L++N+I L+ D AN L++L L NQ+ PG F + L L+LN+ QL
Sbjct 35 LYLNSNQITKLEPGVFDRLAN--LRELHLWGNQLVSLPPGVFDNLANLEKLWLNSNQLT- 91
Query 236 SLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
SL L L N + +L L +L+ + F L T L L L N L + + +FA
Sbjct 92 SLPAGLFDRLVN--LEHLGLCCMKLTELPSGAFDKL--TRLKQLGLDQNQLKSIPDGAFA 147
Query 296 WLPQLEYFFLEYN 308
LP L + +L N
Sbjct 148 RLPSLTHVWLHTN 160
Score = 35.4 bits (80), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 38/142 (27%), Positives = 61/142 (43%), Gaps = 13/142 (9%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L L N+I+K+E F L +L L L N++ L + L N+ +++L+ N+
Sbjct 33 RVLYLNSNQITKLEPGVFDRLANLRELHLWGNQL-VSLPPGVFDNLANLEKLWLNSNQLT 91
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L F + +L+ L L + L + S F L L L L N + +I D L
Sbjct 92 SLPAGLFDRLVNLEHLGLCCMKLTELPS--GAFDKLTRLKQLGLDQNQLKSIPDGAFARL 149
Query 530 EKLEILDLQHNNLARLWKHANP 551
+L +W H NP
Sbjct 150 P----------SLTHVWLHTNP 161
>4k79_B B Variable lymphocyte receptor
Length=220
Score = 62.4 bits (150), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 45/159 (28%), Positives = 71/159 (45%), Gaps = 10/159 (6%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L L L N L L P L++L L L
Sbjct 34 VLYLNSNQITKLEPGVFDRLANLRELHLWGNQLVSL--------PPGVFDNLANLEKLWL 85
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN +P +F L L+ + L L LP+ F+ LK L L +N + S+
Sbjct 86 NSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGAFDKLTRLKQLGLDQNQLKSIPDGA 145
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
F +LT + + NP+DC C I + W+ + H++I
Sbjct 146 FA-RLPSLTHVWLHTNPWDCQCTDILYLSGWVAQ-HSSI 182
Score = 60.1 bits (144), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/159 (29%), Positives = 69/159 (43%), Gaps = 0/159 (0%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDV 82
+ ++C+ S +C+ L VP +PT VL L NQ+ +L F R + L L +
Sbjct 2 ACPSQCSCSGTEVNCAGKSLASVPAGIPTTTRVLYLNSNQITKLEPGVFDRLANLRELHL 61
Query 83 GFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP 142
N + L P + L L+ L L N+L+ L F NL L L + ++ +
Sbjct 62 WGNQLVSLPPGVFDNLANLEKLWLNSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGA 121
Query 143 FVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
F K L L L N L S G +L +L + L N
Sbjct 122 FDKLTRLKQLGLDQNQLKSIPDGAFARLPSLTHVWLHTN 160
Score = 47.4 bits (111), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 45/133 (34%), Positives = 65/133 (49%), Gaps = 7/133 (5%)
Query 176 LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGP 235
L L++N+I L+ D AN L++L L NQ+ PG F + L L+LN+ QL
Sbjct 35 LYLNSNQITKLEPGVFDRLAN--LRELHLWGNQLVSLPPGVFDNLANLEKLWLNSNQLT- 91
Query 236 SLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
SL L L N + +L L +L+ + F L T L L L N L + + +FA
Sbjct 92 SLPAGLFDRLVN--LEHLGLCCMKLTELPSGAFDKL--TRLKQLGLDQNQLKSIPDGAFA 147
Query 296 WLPQLEYFFLEYN 308
LP L + +L N
Sbjct 148 RLPSLTHVWLHTN 160
Score = 35.4 bits (80), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 38/142 (27%), Positives = 61/142 (43%), Gaps = 13/142 (9%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L L N+I+K+E F L +L L L N++ L + L N+ +++L+ N+
Sbjct 33 RVLYLNSNQITKLEPGVFDRLANLRELHLWGNQL-VSLPPGVFDNLANLEKLWLNSNQLT 91
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L F + +L+ L L + L + S F L L L L N + +I D L
Sbjct 92 SLPAGLFDRLVNLEHLGLCCMKLTELPS--GAFDKLTRLKQLGLDQNQLKSIPDGAFARL 149
Query 530 EKLEILDLQHNNLARLWKHANP 551
+L +W H NP
Sbjct 150 P----------SLTHVWLHTNP 161
>4k79_C C Variable lymphocyte receptor
Length=220
Score = 62.4 bits (150), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 45/159 (28%), Positives = 71/159 (45%), Gaps = 10/159 (6%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L L L N L L P L++L L L
Sbjct 34 VLYLNSNQITKLEPGVFDRLANLRELHLWGNQLVSL--------PPGVFDNLANLEKLWL 85
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN +P +F L L+ + L L LP+ F+ LK L L +N + S+
Sbjct 86 NSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGAFDKLTRLKQLGLDQNQLKSIPDGA 145
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
F +LT + + NP+DC C I + W+ + H++I
Sbjct 146 FA-RLPSLTHVWLHTNPWDCQCTDILYLSGWVAQ-HSSI 182
Score = 60.1 bits (144), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/159 (29%), Positives = 69/159 (43%), Gaps = 0/159 (0%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDV 82
+ ++C+ S +C+ L VP +PT VL L NQ+ +L F R + L L +
Sbjct 2 ACPSQCSCSGTEVNCAGKSLASVPAGIPTTTRVLYLNSNQITKLEPGVFDRLANLRELHL 61
Query 83 GFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP 142
N + L P + L L+ L L N+L+ L F NL L L + ++ +
Sbjct 62 WGNQLVSLPPGVFDNLANLEKLWLNSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGA 121
Query 143 FVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
F K L L L N L S G +L +L + L N
Sbjct 122 FDKLTRLKQLGLDQNQLKSIPDGAFARLPSLTHVWLHTN 160
Score = 47.4 bits (111), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 45/133 (34%), Positives = 65/133 (49%), Gaps = 7/133 (5%)
Query 176 LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGP 235
L L++N+I L+ D AN L++L L NQ+ PG F + L L+LN+ QL
Sbjct 35 LYLNSNQITKLEPGVFDRLAN--LRELHLWGNQLVSLPPGVFDNLANLEKLWLNSNQLT- 91
Query 236 SLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
SL L L N + +L L +L+ + F L T L L L N L + + +FA
Sbjct 92 SLPAGLFDRLVN--LEHLGLCCMKLTELPSGAFDKL--TRLKQLGLDQNQLKSIPDGAFA 147
Query 296 WLPQLEYFFLEYN 308
LP L + +L N
Sbjct 148 RLPSLTHVWLHTN 160
Score = 35.4 bits (80), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 38/142 (27%), Positives = 61/142 (43%), Gaps = 13/142 (9%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L L N+I+K+E F L +L L L N++ L + L N+ +++L+ N+
Sbjct 33 RVLYLNSNQITKLEPGVFDRLANLRELHLWGNQL-VSLPPGVFDNLANLEKLWLNSNQLT 91
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L F + +L+ L L + L + S F L L L L N + +I D L
Sbjct 92 SLPAGLFDRLVNLEHLGLCCMKLTELPS--GAFDKLTRLKQLGLDQNQLKSIPDGAFARL 149
Query 530 EKLEILDLQHNNLARLWKHANP 551
+L +W H NP
Sbjct 150 P----------SLTHVWLHTNP 161
>4k5u_A B Variable lymphocyte receptor
Length=220
Score = 62.4 bits (150), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 45/159 (28%), Positives = 71/159 (45%), Gaps = 10/159 (6%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L L L N L L P L++L L L
Sbjct 34 VLYLNSNQITKLEPGVFDRLANLRELHLWGNQLVSL--------PPGVFDNLANLEKLWL 85
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN +P +F L L+ + L L LP+ F+ LK L L +N + S+
Sbjct 86 NSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGAFDKLTRLKQLGLDQNQLKSIPDGA 145
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
F +LT + + NP+DC C I + W+ + H++I
Sbjct 146 FA-RLPSLTHVWLHTNPWDCQCTDILYLSGWVAQ-HSSI 182
Score = 60.1 bits (144), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/159 (29%), Positives = 69/159 (43%), Gaps = 0/159 (0%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDV 82
+ ++C+ S +C+ L VP +PT VL L NQ+ +L F R + L L +
Sbjct 2 ACPSQCSCSGTEVNCAGKSLASVPAGIPTTTRVLYLNSNQITKLEPGVFDRLANLRELHL 61
Query 83 GFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP 142
N + L P + L L+ L L N+L+ L F NL L L + ++ +
Sbjct 62 WGNQLVSLPPGVFDNLANLEKLWLNSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGA 121
Query 143 FVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
F K L L L N L S G +L +L + L N
Sbjct 122 FDKLTRLKQLGLDQNQLKSIPDGAFARLPSLTHVWLHTN 160
Score = 47.4 bits (111), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 45/133 (34%), Positives = 65/133 (49%), Gaps = 7/133 (5%)
Query 176 LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGP 235
L L++N+I L+ D AN L++L L NQ+ PG F + L L+LN+ QL
Sbjct 35 LYLNSNQITKLEPGVFDRLAN--LRELHLWGNQLVSLPPGVFDNLANLEKLWLNSNQLT- 91
Query 236 SLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
SL L L N + +L L +L+ + F L T L L L N L + + +FA
Sbjct 92 SLPAGLFDRLVN--LEHLGLCCMKLTELPSGAFDKL--TRLKQLGLDQNQLKSIPDGAFA 147
Query 296 WLPQLEYFFLEYN 308
LP L + +L N
Sbjct 148 RLPSLTHVWLHTN 160
Score = 35.4 bits (80), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 38/142 (27%), Positives = 61/142 (43%), Gaps = 13/142 (9%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L L N+I+K+E F L +L L L N++ L + L N+ +++L+ N+
Sbjct 33 RVLYLNSNQITKLEPGVFDRLANLRELHLWGNQL-VSLPPGVFDNLANLEKLWLNSNQLT 91
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L F + +L+ L L + L + S F L L L L N + +I D L
Sbjct 92 SLPAGLFDRLVNLEHLGLCCMKLTELPS--GAFDKLTRLKQLGLDQNQLKSIPDGAFARL 149
Query 530 EKLEILDLQHNNLARLWKHANP 551
+L +W H NP
Sbjct 150 P----------SLTHVWLHTNP 161
>4k5u_B A Variable lymphocyte receptor
Length=220
Score = 62.4 bits (150), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 45/159 (28%), Positives = 71/159 (45%), Gaps = 10/159 (6%)
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
+L L++N I + + + L L L L N L L P L++L L L
Sbjct 34 VLYLNSNQITKLEPGVFDRLANLRELHLWGNQLVSL--------PPGVFDNLANLEKLWL 85
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
SN +P +F L L+ + L L LP+ F+ LK L L +N + S+
Sbjct 86 NSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGAFDKLTRLKQLGLDQNQLKSIPDGA 145
Query 630 FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
F +LT + + NP+DC C I + W+ + H++I
Sbjct 146 FA-RLPSLTHVWLHTNPWDCQCTDILYLSGWVAQ-HSSI 182
Score = 60.1 bits (144), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 46/159 (29%), Positives = 69/159 (43%), Gaps = 0/159 (0%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDV 82
+ ++C+ S +C+ L VP +PT VL L NQ+ +L F R + L L +
Sbjct 2 ACPSQCSCSGTEVNCAGKSLASVPAGIPTTTRVLYLNSNQITKLEPGVFDRLANLRELHL 61
Query 83 GFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP 142
N + L P + L L+ L L N+L+ L F NL L L + ++ +
Sbjct 62 WGNQLVSLPPGVFDNLANLEKLWLNSNQLTSLPAGLFDRLVNLEHLGLCCMKLTELPSGA 121
Query 143 FVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
F K L L L N L S G +L +L + L N
Sbjct 122 FDKLTRLKQLGLDQNQLKSIPDGAFARLPSLTHVWLHTN 160
Score = 47.4 bits (111), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 45/133 (34%), Positives = 65/133 (49%), Gaps = 7/133 (5%)
Query 176 LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGP 235
L L++N+I L+ D AN L++L L NQ+ PG F + L L+LN+ QL
Sbjct 35 LYLNSNQITKLEPGVFDRLAN--LRELHLWGNQLVSLPPGVFDNLANLEKLWLNSNQLT- 91
Query 236 SLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
SL L L N + +L L +L+ + F L T L L L N L + + +FA
Sbjct 92 SLPAGLFDRLVN--LEHLGLCCMKLTELPSGAFDKL--TRLKQLGLDQNQLKSIPDGAFA 147
Query 296 WLPQLEYFFLEYN 308
LP L + +L N
Sbjct 148 RLPSLTHVWLHTN 160
Score = 35.4 bits (80), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 38/142 (27%), Positives = 61/142 (43%), Gaps = 13/142 (9%)
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
+L L N+I+K+E F L +L L L N++ L + L N+ +++L+ N+
Sbjct 33 RVLYLNSNQITKLEPGVFDRLANLRELHLWGNQL-VSLPPGVFDNLANLEKLWLNSNQLT 91
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
L F + +L+ L L + L + S F L L L L N + +I D L
Sbjct 92 SLPAGLFDRLVNLEHLGLCCMKLTELPS--GAFDKLTRLKQLGLDQNQLKSIPDGAFARL 149
Query 530 EKLEILDLQHNNLARLWKHANP 551
+L +W H NP
Sbjct 150 P----------SLTHVWLHTNP 161
>5xnp_B B Leucine-rich repeat and fibronectin type-III domain-containing
protein 5
Length=361
Score = 64.3 bits (155), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 80/186 (43%), Gaps = 35/186 (19%)
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
E+ L+ N + R FA + SL L L R + + +P F LRNL L L++N +
Sbjct 42 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFI--TPHAFADLRNLRALHLNSNRLT 99
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I +DM GLS+LH L L +N I
Sbjct 100 KITNDMF--------------------------------SGLSNLHHLILNNNQLTLISS 127
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F D+F L+ +DL NNL T+P VSL +L+L N+I ++ K F +T
Sbjct 128 TAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFS-HLHKMTR 186
Query 640 LDMRFN 645
LD+ N
Sbjct 187 LDVTSN 192
Score = 52.8 bits (125), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 2/178 (1%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C+ L VP ++ L L N + + +F + L L + NTIS + P
Sbjct 24 CAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFA 83
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L+L N L+++++ F+ +NL L L +N + I + F L LDLS+
Sbjct 84 DLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSY 143
Query 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
N L + ++ +L L L +N I + + +L+++SN++++ P
Sbjct 144 NNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHL--HKMTRLDVTSNKLQKLPP 199
Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 50/147 (34%), Positives = 78/147 (53%), Gaps = 13/147 (9%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L++N + +K ++ FAN +SL L LS N I +P F + L L LN+ +L
Sbjct 42 ELRLADNFVTNIKRKD---FANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRL 98
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
+T + L+N + +L L+N+QL+ S+T F + L LDLSYNNL + D+
Sbjct 99 T-KITNDMFSGLSN--LHHLILNNNQLTLISSTAFDDV--FALEELDLSYNNLETIPWDA 153
Query 294 FAWLPQLEYFFLEYNNIQHL----FSH 316
+ L L++N I ++ FSH
Sbjct 154 VEKMVSLHTLSLDHNMIDNIPKGTFSH 180
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/113 (25%), Positives = 60/113 (53%), Gaps = 3/113 (3%)
Query 41 KLTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
+LT++ +D+ + ++ L+ L +NQL + + F L LD+ +N + + + +K
Sbjct 97 RLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEK 156
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
+ L L+L HN + + TF+ +T L + SN +QK+ +P ++ ++
Sbjct 157 MVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVL 209
Score = 34.3 bits (77), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 39/171 (23%), Positives = 71/171 (42%), Gaps = 35/171 (20%)
Query 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT 391
S ++S ++ I +F L+ L L++ N + I ++MF+GL NL +L L+N
Sbjct 63 SLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNN--- 119
Query 392 SLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
N+++ I S AF + LE LDL N L
Sbjct 120 -------------------------NQLTLISSTAFDDVFALEELDLSYN----NLETIP 150
Query 452 WRGLENIFEIY---LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP 499
W +E + ++ L +N + + +F+ + + RL + L+ + P
Sbjct 151 WDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDP 201
>5xnp_A A Leucine-rich repeat and fibronectin type-III domain-containing
protein 5
Length=361
Score = 64.3 bits (155), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 80/186 (43%), Gaps = 35/186 (19%)
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
E+ L+ N + R FA + SL L L R + + +P F LRNL L L++N +
Sbjct 42 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFI--TPHAFADLRNLRALHLNSNRLT 99
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I +DM GLS+LH L L +N I
Sbjct 100 KITNDMF--------------------------------SGLSNLHHLILNNNQLTLISS 127
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F D+F L+ +DL NNL T+P VSL +L+L N+I ++ K F +T
Sbjct 128 TAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFS-HLHKMTR 186
Query 640 LDMRFN 645
LD+ N
Sbjct 187 LDVTSN 192
Score = 52.8 bits (125), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 2/178 (1%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C+ L VP ++ L L N + + +F + L L + NTIS + P
Sbjct 24 CAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFA 83
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L+L N L+++++ F+ +NL L L +N + I + F L LDLS+
Sbjct 84 DLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSY 143
Query 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
N L + ++ +L L L +N I + + +L+++SN++++ P
Sbjct 144 NNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHL--HKMTRLDVTSNKLQKLPP 199
Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 50/147 (34%), Positives = 78/147 (53%), Gaps = 13/147 (9%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L++N + +K ++ FAN +SL L LS N I +P F + L L LN+ +L
Sbjct 42 ELRLADNFVTNIKRKD---FANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRL 98
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
+T + L+N + +L L+N+QL+ S+T F + L LDLSYNNL + D+
Sbjct 99 T-KITNDMFSGLSN--LHHLILNNNQLTLISSTAFDDV--FALEELDLSYNNLETIPWDA 153
Query 294 FAWLPQLEYFFLEYNNIQHL----FSH 316
+ L L++N I ++ FSH
Sbjct 154 VEKMVSLHTLSLDHNMIDNIPKGTFSH 180
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/113 (25%), Positives = 60/113 (53%), Gaps = 3/113 (3%)
Query 41 KLTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
+LT++ +D+ + ++ L+ L +NQL + + F L LD+ +N + + + +K
Sbjct 97 RLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEK 156
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI 150
+ L L+L HN + + TF+ +T L + SN +QK+ +P ++ ++
Sbjct 157 MVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVL 209
Score = 34.3 bits (77), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 39/171 (23%), Positives = 71/171 (42%), Gaps = 35/171 (20%)
Query 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT 391
S ++S ++ I +F L+ L L++ N + I ++MF+GL NL +L L+N
Sbjct 63 SLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNN--- 119
Query 392 SLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
N+++ I S AF + LE LDL N L
Sbjct 120 -------------------------NQLTLISSTAFDDVFALEELDLSYN----NLETIP 150
Query 452 WRGLENIFEIY---LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP 499
W +E + ++ L +N + + +F+ + + RL + L+ + P
Sbjct 151 WDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDP 201
>1m0z_A A Glycoprotein Ib alpha
Length=290
Score = 63.5 bits (153), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 25/181 (14%)
Query 28 CTVS----HEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVG 83
C VS H +C +LT +P DLP + T+L+L+ N L A Y++LT L++
Sbjct 4 CEVSKXXXHLEVNCDKRQLTALPPDLPKDTTILHLSENLLYTFSLATLMPYTRLTQLNLD 63
Query 84 FNTISKLE---------------------PELCQKLPMLKVLNLQHNELSQLSDKTFAFC 122
++KL+ P L Q LP L VL++ N L+ L
Sbjct 64 RCELTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGL 123
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L EL+L N ++ + L L L++N L+ G LENL LLL N
Sbjct 124 GELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENS 183
Query 183 I 183
+
Sbjct 184 L 184
Score = 59.3 bits (142), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 48/161 (30%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHIL 567
L LDLS+N + ++ + + L L +LD+ N L L P+ L+GL L L
Sbjct 79 LGTLDLSHNQLQSL-PLLGQTLPALTVLDVSFNRLTSL--------PLGALRGLGELQEL 129
Query 568 NLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEK 627
L+ N +P + +L+ + L N L LPA + N +L +L LQ+N + ++ K
Sbjct 130 YLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPK 189
Query 628 KVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
FG L NP+ C CE I +F W+ + N+
Sbjct 190 GFFGSHLLPFAFL--HGNPWLCNCE-ILYFRRWLQDNAENV 227
Score = 44.7 bits (104), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 44/129 (34%), Positives = 60/129 (47%), Gaps = 3/129 (2%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C KL QV LP + L+L+HNQL+ LP T LT LDV FN ++ L +
Sbjct 65 CELTKL-QVDGTLPV-LGTLDLSHNQLQSLPLLGQT-LPALTVLDVSFNRLTSLPLGALR 121
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L L+ NEL L L +L L +N + ++ +NL TL L
Sbjct 122 GLGELQELYLKGNELKTLPPGLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQE 181
Query 157 NGLSSTKLG 165
N L + G
Sbjct 182 NSLYTIPKG 190
Score = 43.5 bits (101), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 43/145 (30%), Positives = 70/145 (48%), Gaps = 8/145 (6%)
Query 404 LAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ-ELTGQEWRGLENIFEIY 462
+ ++ L LNL + +++K++ D L L LDL N++ L GQ L + ++
Sbjct 52 MPYTRLTQLNLDRCELTKLQVDGT--LPVLGTLDLSHNQLQSLPLLGQTLPAL-TVLDV- 107
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
S+N+ L + + LQ L L+ LK + P P L L L+NN + +
Sbjct 108 -SFNRLTSLPLGALRGLGELQELYLKGNELKTL--PPGLLTPTPKLEKLSLANNQLTELP 164
Query 523 DDMLEGLEKLEILDLQHNNLARLWK 547
+L GLE L+ L LQ N+L + K
Sbjct 165 AGLLNGLENLDTLLLQENSLYTIPK 189
Score = 41.6 bits (96), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 35/111 (32%), Positives = 52/111 (47%), Gaps = 4/111 (4%)
Query 36 DCSHLKLTQVP---DDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEP 92
D SH +L +P LP +TVL+++ N+L LP +L L + N + L P
Sbjct 83 DLSHNQLQSLPLLGQTLPA-LTVLDVSFNRLTSLPLGALRGLGELQELYLKGNELKTLPP 141
Query 93 ELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
L P L+ L+L +N+L++L NL L L NS+ I F
Sbjct 142 GLLTPTPKLEKLSLANNQLTELPAGLLNGLENLDTLLLQENSLYTIPKGFF 192
>5xws_A A Leucine-rich repeat and fibronectin type-III domain-containing
protein 5
Length=367
Score = 63.5 bits (153), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 80/186 (43%), Gaps = 35/186 (19%)
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
E+ L+ N + R FA + SL L L R + + +P F LRNL L L++N +
Sbjct 38 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFI--TPHAFADLRNLRALHLNSNRLT 95
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I +DM GL S+LH L L +N I
Sbjct 96 KITNDMFSGL--------------------------------SNLHHLILNNNQLTLISS 123
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F D+F L+ +DL NNL T+P VSL +L+L N+I ++ K F +T
Sbjct 124 TAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFS-HLHKMTR 182
Query 640 LDMRFN 645
LD+ N
Sbjct 183 LDVTSN 188
Score = 53.1 bits (126), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 2/178 (1%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C+ L VP ++ L L N + + +F + L L + NTIS + P
Sbjct 20 CAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFA 79
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L+L N L+++++ F+ +NL L L +N + I + F L LDLS+
Sbjct 80 DLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSY 139
Query 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
N L + ++ +L L L +N I + + +L+++SN++++ P
Sbjct 140 NNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHL--HKMTRLDVTSNKLQKLPP 195
Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 52/152 (34%), Positives = 81/152 (53%), Gaps = 14/152 (9%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L++N + +K ++ FAN +SL L LS N I +P F + L L LN+ +L
Sbjct 38 ELRLADNFVTNIKRKD---FANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRL 94
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
+T + L+N + +L L+N+QL+ S+T F + L LDLSYNNL + D+
Sbjct 95 T-KITNDMFSGLSN--LHHLILNNNQLTLISSTAFDDV--FALEELDLSYNNLETIPWDA 149
Query 294 FAWLPQLEYFFLEYNNIQHL----FSHSLHGL 321
+ L L++N I ++ FSH LH +
Sbjct 150 VEKMVSLHTLSLDHNMIDNIPKGTFSH-LHKM 180
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 28/114 (25%), Positives = 60/114 (53%), Gaps = 3/114 (3%)
Query 41 KLTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
+LT++ +D+ + ++ L+ L +NQL + + F L LD+ +N + + + +K
Sbjct 93 RLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEK 152
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
+ L L+L HN + + TF+ +T L + SN +QK+ +P ++ ++
Sbjct 153 MVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLA 206
Score = 34.7 bits (78), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 39/171 (23%), Positives = 71/171 (42%), Gaps = 35/171 (20%)
Query 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT 391
S ++S ++ I +F L+ L L++ N + I ++MF+GL NL +L L+N
Sbjct 59 SLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNN--- 115
Query 392 SLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
N+++ I S AF + LE LDL N L
Sbjct 116 -------------------------NQLTLISSTAFDDVFALEELDLSYN----NLETIP 146
Query 452 WRGLENIFEIY---LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP 499
W +E + ++ L +N + + +F+ + + RL + L+ + P
Sbjct 147 WDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDP 197
>5xnq_A A Leucine-rich repeat and fibronectin type-III domain-containing
protein 5
Length=371
Score = 63.2 bits (152), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 56/186 (30%), Positives = 80/186 (43%), Gaps = 35/186 (19%)
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
E+ L+ N + R FA + SL L L R + + +P F LRNL L L++N +
Sbjct 42 ELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFI--TPHAFADLRNLRALHLNSNRLT 99
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
I +DM GLS+LH L L +N I
Sbjct 100 KITNDMF--------------------------------SGLSNLHHLILNNNQLTLISS 127
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
F D+F L+ +DL NNL T+P VSL +L+L N+I ++ K F +T
Sbjct 128 TAFDDVFALEELDLSYNNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFS-HLHKMTR 186
Query 640 LDMRFN 645
LD+ N
Sbjct 187 LDVTSN 192
Score = 52.4 bits (124), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 45/178 (25%), Positives = 82/178 (46%), Gaps = 2/178 (1%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQ 96
C+ L VP ++ L L N + + +F + L L + NTIS + P
Sbjct 24 CAKKGLLFVPPNIDRRTVELRLADNFVTNIKRKDFANMTSLVDLTLSRNTISFITPHAFA 83
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSH 156
L L+ L+L N L+++++ F+ +NL L L +N + I + F L LDLS+
Sbjct 84 DLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSY 143
Query 157 NGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
N L + ++ +L L L +N I + + +L+++SN++++ P
Sbjct 144 NNLETIPWDAVEKMVSLHTLSLDHNMIDNIPKGTFSHL--HKMTRLDVTSNKLQKLPP 199
Score = 47.4 bits (111), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 52/152 (34%), Positives = 81/152 (53%), Gaps = 14/152 (9%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L++N + +K ++ FAN +SL L LS N I +P F + L L LN+ +L
Sbjct 42 ELRLADNFVTNIKRKD---FANMTSLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRL 98
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
+T + L+N + +L L+N+QL+ S+T F + L LDLSYNNL + D+
Sbjct 99 T-KITNDMFSGLSN--LHHLILNNNQLTLISSTAFDDV--FALEELDLSYNNLETIPWDA 153
Query 294 FAWLPQLEYFFLEYNNIQHL----FSHSLHGL 321
+ L L++N I ++ FSH LH +
Sbjct 154 VEKMVSLHTLSLDHNMIDNIPKGTFSH-LHKM 184
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 28/114 (25%), Positives = 60/114 (53%), Gaps = 3/114 (3%)
Query 41 KLTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
+LT++ +D+ + ++ L+ L +NQL + + F L LD+ +N + + + +K
Sbjct 97 RLTKITNDMFSGLSNLHHLILNNNQLTLISSTAFDDVFALEELDLSYNNLETIPWDAVEK 156
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
+ L L+L HN + + TF+ +T L + SN +QK+ +P ++ ++
Sbjct 157 MVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDPLFQRAQVLA 210
Score = 34.3 bits (77), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 39/171 (23%), Positives = 71/171 (42%), Gaps = 35/171 (20%)
Query 332 SFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT 391
S ++S ++ I +F L+ L L++ N + I ++MF+GL NL +L L+N
Sbjct 63 SLVDLTLSRNTISFITPHAFADLRNLRALHLNSNRLTKITNDMFSGLSNLHHLILNN--- 119
Query 392 SLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
N+++ I S AF + LE LDL N L
Sbjct 120 -------------------------NQLTLISSTAFDDVFALEELDLSYN----NLETIP 150
Query 452 WRGLENIFEIY---LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSP 499
W +E + ++ L +N + + +F+ + + RL + L+ + P
Sbjct 151 WDAVEKMVSLHTLSLDHNMIDNIPKGTFSHLHKMTRLDVTSNKLQKLPPDP 201
>4xgo_A A Anopheles Plasmodium-responsive Leucine-rich repeat
protein 1B
Length=356
Score = 62.8 bits (151), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 77/277 (28%), Positives = 124/277 (45%), Gaps = 36/277 (13%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
+ VLNL Q+ + F + L + FN I L P + Q +P+L VL L N+LS
Sbjct 25 VEVLNLNGLQIEEIDTNAFAYAHTIQKLYMRFNVIRYLPPHVFQNVPLLTVLMLDRNDLS 84
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL-- 170
L F LT + + +N++++I+++ F L L LS N L+ L L
Sbjct 85 SLPPGIFHNTPKLTMMSMSNNNLERIEDDTFQATTALQNLQLSSNRLTHVDLALIPSLFH 144
Query 171 ENLQELLLSNNKIQALKSEELDIFANS----------SLKKLELSSNQIKEFS-----PG 215
N+ LLS I + EELD N+ L L+L N + + + PG
Sbjct 145 VNVSYNLLSTLAI-PIAVEELDASHNTINVVRGPVNVELTILKLQHNNLTDTAWLLNYPG 203
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLE--LANTSIRNLSLSNSQLSTTSNTTFLGLKW 273
L +V L + EK+ + + + L +SN++L F G
Sbjct 204 ------------LVDVDLSYNQLEKITYQHFVKMQRLERLYVSNNRLVALD---FYGRPI 248
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNI 310
L +LDLS+N+L V ++ A +L+Y +L++N+I
Sbjct 249 PTLKVLDLSHNHLMWVEHNQ-AQFDKLQYLYLDHNSI 284
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 58/217 (27%), Positives = 95/217 (44%), Gaps = 27/217 (12%)
Query 433 LEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVAL 492
+EVL+L +I +E+ + I ++Y+ +N L + F VP L LML R L
Sbjct 25 VEVLNLNGLQI-EEIDTNAFAYAHTIQKLYMRFNVIRYLPPHVFQNVPLLTVLMLDRNDL 83
Query 493 KNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPG 552
++ P F LT++ +SNNN+ I DD + L+ L L N L +
Sbjct 84 SSL--PPGIFHNTPKLTMMSMSNNNLERIEDDTFQATTALQNLQLSSNRLTHV------- 134
Query 553 GPIYFLKGLSHLHI-LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVS 611
+ + L H+++ NL S IP+ V + +D N +N + V V
Sbjct 135 -DLALIPSLFHVNVSYNLLSTL--AIPIAVEE-------LDASHNTINVVRGPV---NVE 181
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L L LQ N +T + P L ++D+ +N +
Sbjct 182 LTILKLQHNNLTDTAWLLNYPG---LVDVDLSYNQLE 215
Score = 43.1 bits (100), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 59/271 (22%), Positives = 118/271 (44%), Gaps = 39/271 (14%)
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS---------------F 333
+ ++FA+ ++ ++ +N I++L H + + L L R+
Sbjct 38 IDTNAFAYAHTIQKLYMRFNVIRYLPPHVFQNVPLLTVLMLDRNDLSSLPPGIFHNTPKL 97
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
T S+S +L +I+D +FQ L++L + N + + + L ++ S+ L
Sbjct 98 TMMSMSNNNLERIEDDTFQATTALQNLQLSSNRLTHVDLALIPSLFHVNV-----SYNLL 152
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWR 453
TL V + + +N+ + ++ +E L +L L N LT W
Sbjct 153 STLAIPIAVEELDASHNTINVVRGPVN-VE---------LTILKLQHNN----LTDTAWL 198
Query 454 -GLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
+ ++ LSYN+ ++T F + L+RL + L +D P L+ +LD
Sbjct 199 LNYPGLVDVDLSYNQLEKITYQHFVKMQRLERLYVSNNRLVALDFYGRPIPTLK---VLD 255
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
LS+N++ + + + +KL+ L L HN++
Sbjct 256 LSHNHLMWVEHNQAQ-FDKLQYLYLDHNSIV 285
Score = 37.4 bits (85), Expect = 0.71, Method: Compositional matrix adjust.
Identities = 49/184 (27%), Positives = 72/184 (39%), Gaps = 33/184 (18%)
Query 24 STTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVG 83
ST ++ E D SH + V + +T+L L HN L A Y L +D+
Sbjct 153 STLAIPIAVEELDASHNTINVVRGPVNVELTILKLQHNNLTD--TAWLLNYPGLVDVDLS 210
Query 84 FNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
+N + K+ + K+ L+ L + +N L L I +K
Sbjct 211 YNQLEKITYQHFVKMQRLERLYVSNNRLVALD--------------FYGRPIPTLK---- 252
Query 144 VKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
LDLSHN L + Q Q + LQ L L +N I K + + +LK L
Sbjct 253 -------VLDLSHNHLMWVE-HNQAQFDKLQYLYLDHNSIVTFK-----LSTSHTLKNLT 299
Query 204 LSSN 207
LS N
Sbjct 300 LSHN 303
>7ylf_A A Toll-like receptor 15
Length=180
Score = 60.1 bits (144), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 39/146 (27%), Positives = 69/146 (47%), Gaps = 2/146 (1%)
Query 756 YAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKIIF 815
+ A+I ++ D DW EH + D K C ERDF+ G L I I+ S K++F
Sbjct 15 FDAFISYSEHDADWTKEHLLKKLETD-GFKICYHERDFKPGHPVLGNIFYCIENSHKVLF 73
Query 816 VITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKSHC 875
V++ + + +++++ A + DS+I+V LE++P + R + K
Sbjct 74 VLSPSFV-NSCWXQYELYFAEHRVXXXXQDSLIMVVLEDLPPDSVPQKFSKLRKLLKRKT 132
Query 876 ILNWPVQKERIGAFRHKLQVALGSKN 901
L W ++ + F H+L L + N
Sbjct 133 YLKWSPEEHKQKIFWHQLAAVLKTTN 158
>4cnm_A A TROPHOBLAST GLYCOPROTEIN
Length=299
Score = 62.0 bits (149), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 61/211 (29%), Positives = 100/211 (47%), Gaps = 17/211 (8%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRY---SQLTSLDVG 83
+C+ + C + LT+VP DLP + L LT NQL LPA F R ++L +L++
Sbjct 11 ECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELAALNLS 70
Query 84 FNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNN-- 141
+ + ++ + LP L+ L+L HN L+ LS FAF + S ++ I N+
Sbjct 71 GSRLDEVRAGAFEHLPSLRQLDLSHNPLADLS--PFAFSGSNXXXXXPSPLVELILNHIV 128
Query 142 -PFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSL 199
P +++N S G+ L L+ L+ L L++N L D+ A SL
Sbjct 129 PPEDERQN-----RSFEGMVVAALLAGRALQGLRRLELASNHFLYLPR---DVLAQLPSL 180
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+ L+LS+N + + F + L L L +
Sbjct 181 RHLDLSNNSLVSLTYVSFRNLTHLESLHLED 211
Score = 48.5 bits (114), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 65/250 (26%), Positives = 94/250 (38%), Gaps = 55/250 (22%)
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
R L + +Y + L LT N A++P+ RR PL L L+
Sbjct 24 RNLTEVPTDLPAYVRNLFLTGNQLAVLPA--GAFARR-------------PPLAELAALN 68
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG--------PIYFL------ 558
LS + + + E L L LDL HN LA L A G P+ L
Sbjct 69 LSGSRLDEVRAGAFEHLPSLRQLDLSHNPLADLSPFAFSGSNXXXXXPSPLVELILNHIV 128
Query 559 ----------------------KGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
+ L L L L SN F +P +V L L+ +DL N
Sbjct 129 PPEDERQNRSFEGMVVAALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNN 188
Query 597 NLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRF--NPFDCTCESI 654
+L +L F N L+SL+L+ N + + + L + + NP+ C C +
Sbjct 189 SLVSLTYVSFRNLTHLESLHLEDNALKVLHNGTLA-ELQGLPHIRVFLDNNPWVCDCH-M 246
Query 655 AWFVNWINET 664
A V W+ ET
Sbjct 247 ADMVTWLKET 256
>3v44_A A Toll-like receptor 5b and variable lymphocyte receptor
B.61 chimeric protein
Length=407
Score = 62.8 bits (151), Expect = 7e-09, Method: Compositional matrix adjust.
Identities = 89/347 (26%), Positives = 155/347 (45%), Gaps = 29/347 (8%)
Query 338 ISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG--IKSNMFTGLINLKYLSLS-NSFTSLR 394
+SL S+ ++++ SF L+ L+ L +E PG I++N F GL +L L L N F L
Sbjct 37 LSLNSIAELNETSFSRLQDLQFLKVEQQ-TPGLVIRNNTFRGLSSLIILKLDYNQFLQLE 95
Query 395 TLTNETFVSLAHSPLHILNLTKNKI--SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW 452
T F LA+ L +L LT+ + + + + F L LE+L L N I + +
Sbjct 96 T---GAFNGLAN--LEVLTLTQCNLDGAVLSGNFFKPLTSLEMLVLRDNNIKKIQPASFF 150
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLR--RVALKNV-------DSSPSPFQ 503
+ + L++NK + +LR + L+++ + +PF+
Sbjct 151 LNMRRFHVLDLTFNKVKSICEEDLLNFQGKHFTLLRLSSITLQDMNEYWLGWEKCGNPFK 210
Query 504 PLRNLTILDLSNN----NIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF-L 558
++T LDLS N ++A D + G + ++ N+ + H N P F
Sbjct 211 N-TSITTLDLSGNGFKESMAKRFFDAIAGTKIQSLILSNSYNMGSSFGHTNFKDPDNFTF 269
Query 559 KGL--SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
KGL S + +L + + VF +L+ + L N +N + + F LK L
Sbjct 270 KGLEASGVKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNAFWGLTHLKELA 329
Query 617 LQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
L N + SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 330 LDTNQLKSVPDGIF-DRLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 375
Score = 51.2 bits (121), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 81/326 (25%), Positives = 136/326 (42%), Gaps = 25/326 (8%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+V A C + L QVP+ LP ++ ++L+ N + L +F+R L L V T
Sbjct 7 ECSVIGYNAICINRGLHQVPE-LPAHVNYVDLSLNSIAELNETSFSRLQDLQFLKVEQQT 65
Query 87 IS-KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQK--IKNNPF 143
+ + L L +L L +N+ QL F NL L L ++ + N F
Sbjct 66 PGLVIRNNTFRGLSSLIILKLDYNQFLQLETGAFNGLANLEVLTLTQCNLDGAVLSGNFF 125
Query 144 VKQKNLITLDLSHNGLSSTKLGTQ-VQLENLQELLLSNNKIQALKSEELDIFANSSLKKL 202
+L L L N + + + + + L L+ NK++++ E+L F L
Sbjct 126 KPLTSLEMLVLRDNNIKKIQPASFFLNMRRFHVLDLTFNKVKSICEEDLLNFQGKHFTLL 185
Query 203 ELSS---NQIKEFSPGCFHAIGRLFG------LFLNNVQLGPSLTEKLCLELANTSIRNL 253
LSS + E+ G + G F L L+ S+ ++ +A T I++L
Sbjct 186 RLSSITLQDMNEYWLG-WEKCGNPFKNTSITTLDLSGNGFKESMAKRFFDAIAGTKIQSL 244
Query 254 SLSNS----------QLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYF 303
LSNS N TF GL+ + + DLS + + + F+ LE
Sbjct 245 ILSNSYNMGSSFGHTNFKDPDNFTFKGLEASGVKTCDLSKSKIFALLKSVFSHFTDLEQL 304
Query 304 FLEYNNIQHLFSHSLHGLFNVRYLNL 329
L N I + ++ GL +++ L L
Sbjct 305 TLAQNEINKIDDNAFWGLTHLKELAL 330
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 88/336 (26%), Positives = 134/336 (40%), Gaps = 66/336 (20%)
Query 202 LELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLS------L 255
++LS N I E + F + L FL Q P L + N + R LS L
Sbjct 35 VDLSLNSIAELNETSFSRLQDL--QFLKVEQQTPGLV------IRNNTFRGLSSLIILKL 86
Query 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN--VVGNDSFAWLPQLEYFFLEYNNIQHL 313
+Q F GL NL +L L+ NL+ V+ + F L LE L NNI+ +
Sbjct 87 DYNQFLQLETGAFNGL--ANLEVLTLTQCNLDGAVLSGNFFKPLTSLEMLVLRDNNIKKI 144
Query 314 FSHSLHGLFNVRYLNL--------------------KRSFTKQSISLASLPKIDDFSFQW 353
S N+R ++ + FT +S +L ++++ W
Sbjct 145 QPASF--FLNMRRFHVLDLTFNKVKSICEEDLLNFQGKHFTLLRLSSITLQDMNEYWLGW 202
Query 354 LKC--------LEHLNMEDNDIPGIKSNM----FTGLINLKYLSL--SNSF--------T 391
KC + L++ N G K +M F + K SL SNS+ T
Sbjct 203 EKCGNPFKNTSITTLDLSGN---GFKESMAKRFFDAIAGTKIQSLILSNSYNMGSSFGHT 259
Query 392 SLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
+ + N TF L S + +L+K+KI + FS LE L L NEI +
Sbjct 260 NFKDPDNFTFKGLEASGVKTCDLSKSKIFALLKSVFSHFTDLEQLTLAQNEINKIDDNAF 319
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
W GL ++ E+ L N+ + F + SLQ++ L
Sbjct 320 W-GLTHLKELALDTNQLKSVPDGIFDRLTSLQKIWL 354
>2j67_A A TOLL LIKE RECEPTOR 10
Length=178
Score = 59.7 bits (143), Expect = 9e-09, Method: Compositional matrix adjust.
Identities = 42/144 (29%), Positives = 71/144 (49%), Gaps = 2/144 (1%)
Query 756 YAAYIIHAYKDKDWVW-EHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSIKRSRKII 814
+ A+I ++ D WV E ++EKED S+ CL E F+ G E IV+ I++S K I
Sbjct 36 FHAFISYSEHDSLWVKNELIPNLEKEDXSILICLYESYFDPGKSISENIVSFIEKSYKSI 95
Query 815 FVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKSH 874
FV++ + +++ C ++ + A IIL+ LE IP Y + + + +
Sbjct 96 FVLSPNFVQNEWC-HYEFYFAHHNXXXXXXXHIILILLEPIPFYCIPTRYHKLKALLEKK 154
Query 875 CILNWPVQKERIGAFRHKLQVALG 898
L WP + + G F L+ A+
Sbjct 155 AYLEWPKDRRKCGLFWANLRAAIN 178
>3g3a_A A Variable lymphocyte receptor VLRB.2D
Length=178
Score = 59.3 bits (142), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 37/108 (34%), Positives = 55/108 (51%), Gaps = 0/108 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DCS L VP +PT VL L NQ+ +L F R +QLT LD+ N
Sbjct 13 SQCSCSGTTVDCSGKSLASVPTGIPTTTQVLYLYDNQITKLEPGVFDRLTQLTRLDLDNN 72
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
++ L + KL L L+L N+L + F +LT + L++N
Sbjct 73 QLTVLPAGVFDKLTQLTQLSLNDNQLKSIPRGAFDNLKSLTHIWLLNN 120
Score = 56.2 bits (134), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 50/99 (51%), Gaps = 1/99 (1%)
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+L L N ++ VF L +L +DL N L LPA VF+ L L+L N + S
Sbjct 41 QVLYLYDNQITKLEPGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKS 100
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ + F ++LT + + NP+DC C I + WI++
Sbjct 101 IPRGAFD-NLKSLTHIWLLNNPWDCACSDILYLSRWISQ 138
Score = 33.1 bits (74), Expect = 8.0, Method: Compositional matrix adjust.
Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 5/70 (7%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
P F L LT LDL NN + + + + L +L L L N L + P G L
Sbjct 55 PGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKSI-----PRGAFDNL 109
Query 559 KGLSHLHILN 568
K L+H+ +LN
Sbjct 110 KSLTHIWLLN 119
>3g3a_C C Variable lymphocyte receptor VLRB.2D
Length=178
Score = 59.3 bits (142), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 37/108 (34%), Positives = 55/108 (51%), Gaps = 0/108 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DCS L VP +PT VL L NQ+ +L F R +QLT LD+ N
Sbjct 13 SQCSCSGTTVDCSGKSLASVPTGIPTTTQVLYLYDNQITKLEPGVFDRLTQLTRLDLDNN 72
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
++ L + KL L L+L N+L + F +LT + L++N
Sbjct 73 QLTVLPAGVFDKLTQLTQLSLNDNQLKSIPRGAFDNLKSLTHIWLLNN 120
Score = 56.2 bits (134), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 50/99 (51%), Gaps = 1/99 (1%)
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+L L N ++ VF L +L +DL N L LPA VF+ L L+L N + S
Sbjct 41 QVLYLYDNQITKLEPGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKS 100
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ + F ++LT + + NP+DC C I + WI++
Sbjct 101 IPRGAFD-NLKSLTHIWLLNNPWDCACSDILYLSRWISQ 138
Score = 33.1 bits (74), Expect = 8.0, Method: Compositional matrix adjust.
Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 5/70 (7%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
P F L LT LDL NN + + + + L +L L L N L + P G L
Sbjct 55 PGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKSI-----PRGAFDNL 109
Query 559 KGLSHLHILN 568
K L+H+ +LN
Sbjct 110 KSLTHIWLLN 119
>3g3a_E E Variable lymphocyte receptor VLRB.2D
Length=178
Score = 59.3 bits (142), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 37/108 (34%), Positives = 55/108 (51%), Gaps = 0/108 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DCS L VP +PT VL L NQ+ +L F R +QLT LD+ N
Sbjct 13 SQCSCSGTTVDCSGKSLASVPTGIPTTTQVLYLYDNQITKLEPGVFDRLTQLTRLDLDNN 72
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
++ L + KL L L+L N+L + F +LT + L++N
Sbjct 73 QLTVLPAGVFDKLTQLTQLSLNDNQLKSIPRGAFDNLKSLTHIWLLNN 120
Score = 56.2 bits (134), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 50/99 (51%), Gaps = 1/99 (1%)
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+L L N ++ VF L +L +DL N L LPA VF+ L L+L N + S
Sbjct 41 QVLYLYDNQITKLEPGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKS 100
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ + F ++LT + + NP+DC C I + WI++
Sbjct 101 IPRGAFD-NLKSLTHIWLLNNPWDCACSDILYLSRWISQ 138
Score = 33.1 bits (74), Expect = 8.0, Method: Compositional matrix adjust.
Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 5/70 (7%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
P F L LT LDL NN + + + + L +L L L N L + P G L
Sbjct 55 PGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKSI-----PRGAFDNL 109
Query 559 KGLSHLHILN 568
K L+H+ +LN
Sbjct 110 KSLTHIWLLN 119
>1o77_C C TOLL-LIKE RECEPTOR 2
Length=146
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 38/146 (26%), Positives = 71/146 (49%), Gaps = 4/146 (3%)
Query 756 YAAYIIHAYKDKDWVWEHFSSMEKED--QSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
Y A++ ++ +D WV E+ E E+ K CL +RDF G + ++ I++SI++S K
Sbjct 3 YDAFVSYSERDAYWV-ENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKT 61
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
+FV++ + +K K +++ + IL+ LE I + C R + +
Sbjct 62 VFVLSENFVKSEWSK-YELDFXXXXXXXXXXXAAILILLEPIEKKAIPQRFCKLRKIMNT 120
Query 874 HCILNWPVQKERIGAFRHKLQVALGS 899
L WP+ + + F L+ A+ S
Sbjct 121 KTYLEWPMDEAQREGFWVNLRAAIKS 146
>3g39_A A Variable lymphocyte receptor VLRB.2D
Length=170
Score = 58.9 bits (141), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 37/107 (35%), Positives = 54/107 (50%), Gaps = 0/107 (0%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
+C+ S DCS L VP +PT VL L NQ+ +L F R +QLT LD+ N
Sbjct 6 QCSCSGTTVDCSGKSLASVPTGIPTTTQVLYLYDNQITKLEPGVFDRLTQLTRLDLDNNQ 65
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
++ L + KL L L+L N+L + F +LT + L++N
Sbjct 66 LTVLPAGVFDKLTQLTQLSLNDNQLKSIPRGAFDNLKSLTHIWLLNN 112
Score = 55.8 bits (133), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 50/99 (51%), Gaps = 1/99 (1%)
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+L L N ++ VF L +L +DL N L LPA VF+ L L+L N + S
Sbjct 33 QVLYLYDNQITKLEPGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKS 92
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ + F ++LT + + NP+DC C I + WI++
Sbjct 93 IPRGAFD-NLKSLTHIWLLNNPWDCACSDILYLSRWISQ 130
Score = 32.7 bits (73), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 5/70 (7%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
P F L LT LDL NN + + + + L +L L L N L + P G L
Sbjct 47 PGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKSI-----PRGAFDNL 101
Query 559 KGLSHLHILN 568
K L+H+ +LN
Sbjct 102 KSLTHIWLLN 111
>1o77_E E TOLL-LIKE RECEPTOR 2
Length=146
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 38/146 (26%), Positives = 71/146 (49%), Gaps = 4/146 (3%)
Query 756 YAAYIIHAYKDKDWVWEHFSSMEKED--QSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
Y A++ ++ +D WV E+ E E+ K CL +RDF G + ++ I++SI++S K
Sbjct 3 YDAFVSYSERDAYWV-ENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKT 61
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
+FV++ + +K K +++ + IL+ LE I + C R + +
Sbjct 62 VFVLSENFVKSEWSK-YELDFXXXXLFXXXXXAAILILLEPIEKKAIPQRFCKLRKIMNT 120
Query 874 HCILNWPVQKERIGAFRHKLQVALGS 899
L WP+ + + F L+ A+ S
Sbjct 121 KTYLEWPMDEAQREGFWVNLRAAIKS 146
>3o6n_A A APL1
Length=390
Score = 62.0 bits (149), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 67/258 (26%), Positives = 112/258 (43%), Gaps = 44/258 (17%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
+ +LNL Q+ + F + L +GFN I L P + Q +P+L VL L+ N+LS
Sbjct 71 VELLNLNDLQIEEIDTYAFAYAHTIQKLYMGFNAIRYLPPHVFQNVPLLTVLVLERNDLS 130
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
L F LT L + +N++++I+++ F +L L LS N L T V L
Sbjct 131 SLPRGIFHNTPKLTTLSMSNNNLERIEDDTFQATTSLQNLQLSSNRL------THVDLSL 184
Query 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ 232
+ L +N L + + I ++++L+ S N I NV
Sbjct 185 IPSLFHANVSYNLLSTLAIPI----AVEELDASHNSI--------------------NVV 220
Query 233 LGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGND 292
GP E L+L + ++ ++T +L L + L +DLSYN L +
Sbjct 221 RGPVNVELTILKLQHNNL-------------TDTAWL-LNYPGLVEVDLSYNELEKIMYH 266
Query 293 SFAWLPQLEYFFLEYNNI 310
F + +LE ++ N +
Sbjct 267 PFVKMQRLERLYISNNRL 284
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 70/319 (22%), Positives = 141/319 (44%), Gaps = 51/319 (16%)
Query 252 NLSLSNSQLSTTSNTTFLGL------KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFL 305
+++L+N ++ T N+T L + + +L+L+ + + +FA+ ++ ++
Sbjct 41 DITLNNQKIVTFKNSTMRKLPAALLDSFRQVELLNLNDLQIEEIDTYAFAYAHTIQKLYM 100
Query 306 EYNNIQHLFSHSLHGLFNVRYLNLKRS---------------FTKQSISLASLPKIDDFS 350
+N I++L H + + L L+R+ T S+S +L +I+D +
Sbjct 101 GFNAIRYLPPHVFQNVPLLTVLVLERNDLSSLPRGIFHNTPKLTTLSMSNNNLERIEDDT 160
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
FQ L++L + N + + ++ L + S+ L TL V + +
Sbjct 161 FQATTSLQNLQLSSNRLTHVDLSLIPSLFHANV-----SYNLLSTLAIPIAVEELDASHN 215
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWR-GLENIFEIYLSYNKYL 469
+N+ + ++ L +L L N LT W + E+ LSYN+
Sbjct 216 SINVVRGPVN----------VELTILKLQHNN----LTDTAWLLNYPGLVEVDLSYNELE 261
Query 470 QLTRNSFALVPSLQRLML---RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
++ + F + L+RL + R VAL QP+ L +LDLS+N++ ++ +
Sbjct 262 KIMYHPFVKMQRLERLYISNNRLVALNLYG------QPIPTLKVLDLSHNHLLHVERNQP 315
Query 527 EGLEKLEILDLQHNNLARL 545
+ ++LE L L HN++ L
Sbjct 316 Q-FDRLENLYLDHNSIVTL 333
Score = 41.2 bits (95), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 66/255 (26%), Positives = 104/255 (41%), Gaps = 37/255 (15%)
Query 395 TLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG 454
TL N+ V+ +S T K+ D+F + L + DL + EI +
Sbjct 43 TLNNQKIVTFKNS-------TMRKLPAALLDSFRQVELLNLNDLQIEEID----TYAFAY 91
Query 455 LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLS 514
I ++Y+ +N L + F VP L L+L R L ++ F LT L +S
Sbjct 92 AHTIQKLYMGFNAIRYLPPHVFQNVPLLTVLVLERNDLSSLPRGI--FHNTPKLTTLSMS 149
Query 515 NNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI-LNLESNG 573
NNN+ I DD + L+ L L N L + + + L H ++ NL S
Sbjct 150 NNNLERIEDDTFQATTSLQNLQLSSNRLTHV--------DLSLIPSLFHANVSYNLLSTL 201
Query 574 FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPA 633
IP+ V + +D N++N + V V L L LQ N +T + P
Sbjct 202 --AIPIAVEE-------LDASHNSINVVRGPV---NVELTILKLQHNNLTDTAWLLNYPG 249
Query 634 FRNLTELDMRFNPFD 648
L E+D+ +N +
Sbjct 250 ---LVEVDLSYNELE 261
Score = 37.4 bits (85), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 50/184 (27%), Positives = 74/184 (40%), Gaps = 33/184 (18%)
Query 24 STTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVG 83
ST ++ E D SH + V + +T+L L HN L A Y L +D+
Sbjct 199 STLAIPIAVEELDASHNSINVVRGPVNVELTILKLQHNNLTD--TAWLLNYPGLVEVDLS 256
Query 84 FNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
+N + K+ K+ L+ L + +N L L+L I +K
Sbjct 257 YNELEKIMYHPFVKMQRLERLYISNNR--------------LVALNLYGQPIPTLK---- 298
Query 144 VKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
LDLSHN L + Q Q + L+ L L +N I LK + + +LK L
Sbjct 299 -------VLDLSHNHLLHVE-RNQPQFDRLENLYLDHNSIVTLK-----LSTHHTLKNLT 345
Query 204 LSSN 207
LS N
Sbjct 346 LSHN 349
Score = 37.0 bits (84), Expect = 0.99, Method: Compositional matrix adjust.
Identities = 67/255 (26%), Positives = 115/255 (45%), Gaps = 35/255 (14%)
Query 343 LPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSL-RTLTNET 400
+ +ID ++F + ++ L M N I + ++F + L L L N +SL R + + T
Sbjct 81 IEEIDTYAFAYAHTIQKLYMGFNAIRYLPPHVFQNVPLLTVLVLERNDLSSLPRGIFHNT 140
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
L L+++ N + +IE D F L+ L L N LT + + ++F
Sbjct 141 ------PKLTTLSMSNNNLERIEDDTFQATTSLQNLQLSSNR----LTHVDLSLIPSLFH 190
Query 461 IYLSYN-----------KYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRN-- 507
+SYN + L + NS +V + L + L++ + + + + L N
Sbjct 191 ANVSYNLLSTLAIPIAVEELDASHNSINVVRGPVNVELTILKLQHNNLTDTAW--LLNYP 248
Query 508 -LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLK--GLSHL 564
L +DLS N + I +++LE L + +N L L + G PI LK LSH
Sbjct 249 GLVEVDLSYNELEKIMYHPFVKMQRLERLYISNNRLVALNLY---GQPIPTLKVLDLSHN 305
Query 565 HILNLESN--GFDEI 577
H+L++E N FD +
Sbjct 306 HLLHVERNQPQFDRL 320
>7r54_B B Toll-like receptor 8
Length=807
Score = 62.8 bits (151), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 169/744 (23%), Positives = 283/744 (38%), Gaps = 164/744 (22%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N P
Sbjct 20 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHN------PN 73
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
N ++D F NL EL L N + +I P ++L L
Sbjct 74 XXXXXXXXXXXXXGLN----ITDGAFLNLKNLRELLLEDNQLPQI---PSGLPESLTELS 126
Query 154 LSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
L N + + +L NL+ L L+ N E+ +I
Sbjct 127 LIQNNIYNITKEGISRLINLKNLYLAWNCYXXXXCEKTNI-------------------E 167
Query 214 PGCFHAIGR---LFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLG 270
G F + L F + + P L +S+R L LSN+Q+ S F G
Sbjct 168 DGVFETLTNLELLSLSFNSLSHVPPKLP---------SSLRKLFLSNTQIKYISEEDFKG 218
Query 271 LKWTNLTMLDLSYN------------------NLNVVGNDSFAW--LPQLEYFFLEYNNI 310
L NLT+LDLS N ++N+ D FA+ L QL Y L ++
Sbjct 219 L--INLTLLDLSGNCPRCFNAPFPCVPCDGGASINI---DRFAFQNLTQLRYLNLSSTSL 273
Query 311 QHLFSHSLHGLFNVRYLNLKRSFTKQSIS----LASLPKID--DFSFQWLKC--LEHLNM 362
+ + + + +++ L+L+ ++ I+ L LP+++ D SF ++K +H+N+
Sbjct 274 RKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINI 333
Query 363 EDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILNLTKNKISK 421
N F+ L++L+ L L + L + F L P L +NL N I +
Sbjct 334 SRN---------FSKLLSLRALHLRGYV--FQELREDDFQPLMQLPNLSTINLGINFIKQ 382
Query 422 IESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGL----------------------ENIF 459
I+ F +LE++ L N I N +
Sbjct 383 IDFKLFQNFSNLEIIYLSENRISPLXXXXXXXXXXXXXXXXXXXXXXXXXXXXDPHSNFY 442
Query 460 EIY--------LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS-------SPSPFQP 504
+Y K L L+ NS + Q L +A N+ + S + F
Sbjct 443 HFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSA 502
Query 505 LRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
+ ++ LDL+NN + N L L LE+LDL +N + ++ A + F++ ++L
Sbjct 503 IPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYN--SHYFRIAGVTHHLEFIQNFTNL 560
Query 565 HILNLESNGF-------------------------------DEIPVEVFKDLFELKIIDL 593
+LNL N D + +FK L L +DL
Sbjct 561 KVLNLSHNNIYTLTXKYNLESKSLVELVFSGNRLDILWXXXDNRYISIFKGLKNLTRLDL 620
Query 594 GLNNLNTLPASVF-NNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCE 652
LN L +P F N SL L++ N++ + F L LD+R N +
Sbjct 621 SLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQ-QFPRLELLDLRGNKLLFLTD 679
Query 653 SIAWFVNWINE---THTNIPELSS 673
S++ F + + +H I L S
Sbjct 680 SLSDFTSSLRTLLLSHNRISHLPS 703
Score = 61.2 bits (147), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 95/365 (26%), Positives = 152/365 (42%), Gaps = 78/365 (21%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L++ N I I N F L ++ L+LS + ++ + L+ F ++ H + L+LT N++
Sbjct 460 LDLSLNSIFFIGPNQFENLPDIACLNLSAN-SNAQVLSGTEFSAIPH--VKYLDLTNNRL 516
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTG-----QEWRGLENIFEIYLSYNKYLQLT-- 472
+ A + L LEVLDL N + G + + N+ + LS+N LT
Sbjct 517 DFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTXK 576
Query 473 -----RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI------ 521
++ LV S RL + N S F+ L+NLT LDLS N + +I
Sbjct 577 YNLESKSLVELVFSGNRLDILWXXXDN--RYISIFKGLKNLTRLDLSLNRLKHIPNEAFL 634
Query 522 -----------NDDML--------EGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
ND+ML + +LE+LDL+ N L ++ LS
Sbjct 635 NLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKL------------LFLTDSLS 682
Query 563 HLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLI 622
L+ + L N ++ LP+ SLK L+L NL+
Sbjct 683 DF--------------------TSSLRTLLLSHNRISHLPSGXXXXXSSLKHLDLSSNLL 722
Query 623 TSVEKKVF-GPAFRNLTELDMRFNPFDCTCESIAWFVNWINE-THTNIPELSSHYLCNTP 680
++ K L+ L++ NPF+CTC+ I F W++E + IP L +C +P
Sbjct 723 KTINKSALETKTTTKLSMLELHGNPFECTCD-IGDFRRWMDEHLNVKIPRLVD-VICASP 780
Query 681 PHYHG 685
G
Sbjct 781 GDQRG 785
Score = 43.1 bits (100), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 43/157 (27%), Positives = 70/157 (45%), Gaps = 25/157 (16%)
Query 52 NITVLNLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
N+T L+L+ N+L+ +P F + LT L + N + L Q+ P L++L+L+ N+
Sbjct 614 NLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNK 673
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L+D F ++L TL LSHN +S G
Sbjct 674 LLFLTDSLSDFTSSLR------------------------TLLLSHNRISHLPSGXXXXX 709
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+L+ L LS+N ++ + L+ + L LEL N
Sbjct 710 SSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGN 746
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 69/270 (26%), Positives = 110/270 (41%), Gaps = 18/270 (7%)
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQ-LSDKTFAFCTNLTELHLMSNSIQK 137
+LD+ N+I + P + LP + LNL N +Q LS F+ ++ L L +N +
Sbjct 459 ALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDF 518
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE------NLQELLLSNNKIQALKSEEL 191
+ + +L LDLS+N G LE NL+ L LS+N I L +
Sbjct 519 DNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTXKY- 577
Query 192 DIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIR 251
+ SL +L S N++ + +F N +L SL + N +
Sbjct 578 -NLESKSLVELVFSGNRLDILWXXXDNRYISIFKGLKNLTRLDLSLNR--LKHIPNEAFL 634
Query 252 NLSLSNSQLSTTSNTTFLGLKWT------NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFL 305
NL S ++L N WT L +LDL N L + + + L L
Sbjct 635 NLPASLTELHINDNMLKF-FNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLL 693
Query 306 EYNNIQHLFSHSLHGLFNVRYLNLKRSFTK 335
+N I HL S ++++L+L + K
Sbjct 694 SHNRISHLPSGXXXXXSSLKHLDLSSNLLK 723
Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 68/248 (27%), Positives = 109/248 (44%), Gaps = 23/248 (9%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT----ISKLEP--ELCQKLPMLKVLNL 106
+ L+LT+N+L A+ T S L LD+ +N+ I+ + E Q LKVLNL
Sbjct 506 VKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNL 565
Query 107 QHNELSQLSDKTFAFCTNLTELHLMSNSIQKI---KNNPFVK----QKNLITLDLSHNGL 159
HN + L+ K +L EL N + + +N ++ KNL LDLS N L
Sbjct 566 SHNNIYTLTXKYNLESKSLVELVFSGNRLDILWXXXDNRYISIFKGLKNLTRLDLSLNRL 625
Query 160 SSTKLGTQVQL-ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH 218
+ L +L EL +++N ++ L F L+ L+L N++ +
Sbjct 626 KHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFP--RLELLDLRGNKLLFLTDSLSD 683
Query 219 AIGRLFGLFL--NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNL 276
L L L N + PS +S+++L LS++ L T + + T L
Sbjct 684 FTSSLRTLLLSHNRISHLPS-----GXXXXXSSLKHLDLSSNLLKTINKSALETKTTTKL 738
Query 277 TMLDLSYN 284
+ML+L N
Sbjct 739 SMLELHGN 746
Score = 35.8 bits (81), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 50/168 (30%), Positives = 72/168 (43%), Gaps = 10/168 (6%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTS-------LDVGFNTISKLEPELCQKLPMLKV 103
TN+ VLNL+HN + L L LD+ + + + L L
Sbjct 558 TNLKVLNLSHNNIYTLTXKYNLESKSLVELVFSGNRLDILWXXXDNRYISIFKGLKNLTR 617
Query 104 LNLQHNELSQLSDKTFA-FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSST 162
L+L N L + ++ F +LTELH+ N ++ + L LDL N L
Sbjct 618 LDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFL 677
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+L+ LLLS+N+I L S SSLK L+LSSN +K
Sbjct 678 TDSLSDFTSSLRTLLLSHNRISHLPSGX--XXXXSSLKHLDLSSNLLK 723
>1o77_B B TOLL-LIKE RECEPTOR 2
Length=146
Score = 58.2 bits (139), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 38/146 (26%), Positives = 71/146 (49%), Gaps = 4/146 (3%)
Query 756 YAAYIIHAYKDKDWVWEHFSSMEKED--QSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
Y A++ ++ +D WV E+ E E+ K CL +RDF G + ++ I++SI++S K
Sbjct 3 YDAFVSYSERDAYWV-ENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKT 61
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
+FV++ + +K K +++ + IL+ LE I + C R + +
Sbjct 62 VFVLSENFVKSEWSK-YELXXXXXXLFXXXXXAAILILLEPIEKKAIPQRFCKLRKIMNT 120
Query 874 HCILNWPVQKERIGAFRHKLQVALGS 899
L WP+ + + F L+ A+ S
Sbjct 121 KTYLEWPMDEAQREGFWVNLRAAIKS 146
>3g3b_E E variable lymphocyte receptor VLRB.2D
Length=170
Score = 58.5 bits (140), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 36/108 (33%), Positives = 55/108 (51%), Gaps = 0/108 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DCS L VP +PT VL L N++ +L F R +QLT LD+ N
Sbjct 5 SQCSCSGTTVDCSGKSLASVPTGIPTTTQVLYLYDNRITKLEPGVFDRLTQLTRLDLDNN 64
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
++ L + KL L L+L N+L + F +LT + L++N
Sbjct 65 QLTVLPAGVFDKLTQLTQLSLNDNQLKSIPRGAFDNLRSLTHIWLLNN 112
Score = 48.5 bits (114), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 48/99 (48%), Gaps = 1/99 (1%)
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+L L N ++ VF L +L +DL N L LPA VF+ L L+L N + S
Sbjct 33 QVLYLYDNRITKLEPGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKS 92
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ + F R+LT + + NP+D I + WI++
Sbjct 93 IPRGAFD-NLRSLTHIWLLNNPWDXXXXXILYLSRWISQ 130
Score = 33.5 bits (75), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 26/83 (31%), Positives = 39/83 (47%), Gaps = 5/83 (6%)
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
T+D S L+S G Q L L +N+I L+ D + L +L+L +NQ+
Sbjct 13 TVDCSGKSLASVPTGIPT---TTQVLYLYDNRITKLEPGVFDRL--TQLTRLDLDNNQLT 67
Query 211 EFSPGCFHAIGRLFGLFLNNVQL 233
G F + +L L LN+ QL
Sbjct 68 VLPAGVFDKLTQLTQLSLNDNQL 90
>5wk4_B A Variable lymphocyte receptor 39
Length=201
Score = 58.9 bits (141), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 34/101 (34%), Positives = 50/101 (50%), Gaps = 1/101 (1%)
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L+ L LN+ N +P+ VF L +L + L N LPA VF+ L L L N
Sbjct 61 LTALTFLNVGDNQLSALPIGVFDRLAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTN 120
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWI 661
+ S+ + F ++LT + + NP+DC C I + NWI
Sbjct 121 QLKSIPRGAFD-NLKSLTHIYLFNNPWDCECSDILYLKNWI 160
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 62/132 (47%), Gaps = 0/132 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ +C L VP +PT+ L L +NQ+ +L F + LT L+VG N
Sbjct 13 SQCSCRGTTVNCDSRSLASVPAGIPTDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDN 72
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+S L + +L L L L HN+ + L F LT L L +N ++ I F
Sbjct 73 QLSALPIGVFDRLAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTNQLKSIPRGAFDN 132
Query 146 QKNLITLDLSHN 157
K+L + L +N
Sbjct 133 LKSLTHIYLFNN 144
Score = 38.1 bits (87), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 9/128 (7%)
Query 395 TLTNETFVSLAHSPLHI------LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
T N SLA P I L L N+I+K+E F L L L++G N++
Sbjct 20 TTVNCDSRSLASVPAGIPTDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDNQLSALPI 79
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
G R L + + LS+N++ L F +P L L+L LK++ F L++L
Sbjct 80 GVFDR-LAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTNQLKSIPR--GAFDNLKSL 136
Query 509 TILDLSNN 516
T + L NN
Sbjct 137 THIYLFNN 144
Score = 37.4 bits (85), Expect = 0.36, Method: Compositional matrix adjust.
Identities = 33/108 (31%), Positives = 50/108 (46%), Gaps = 2/108 (2%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
T+ L L +N I K++ F L L++ N LS+ +G +L L L LS+N+
Sbjct 38 TDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDNQLSALPIGVFDRLAQLTRLGLSHNQ 97
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AL + D L L L +NQ+K G F + L ++L N
Sbjct 98 FTALPAGVFDKLP--KLTHLVLHTNQLKSIPRGAFDNLKSLTHIYLFN 143
>5wk4_F F Variable lymphocyte receptor 39
Length=201
Score = 58.9 bits (141), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 34/101 (34%), Positives = 50/101 (50%), Gaps = 1/101 (1%)
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L+ L LN+ N +P+ VF L +L + L N LPA VF+ L L L N
Sbjct 61 LTALTFLNVGDNQLSALPIGVFDRLAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTN 120
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWI 661
+ S+ + F ++LT + + NP+DC C I + NWI
Sbjct 121 QLKSIPRGAFD-NLKSLTHIYLFNNPWDCECSDILYLKNWI 160
Score = 56.2 bits (134), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 62/132 (47%), Gaps = 0/132 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ +C L VP +PT+ L L +NQ+ +L F + LT L+VG N
Sbjct 13 SQCSCRGTTVNCDSRSLASVPAGIPTDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDN 72
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+S L + +L L L L HN+ + L F LT L L +N ++ I F
Sbjct 73 QLSALPIGVFDRLAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTNQLKSIPRGAFDN 132
Query 146 QKNLITLDLSHN 157
K+L + L +N
Sbjct 133 LKSLTHIYLFNN 144
Score = 38.1 bits (87), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 9/128 (7%)
Query 395 TLTNETFVSLAHSPLHI------LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
T N SLA P I L L N+I+K+E F L L L++G N++
Sbjct 20 TTVNCDSRSLASVPAGIPTDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDNQLSALPI 79
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
G R L + + LS+N++ L F +P L L+L LK++ F L++L
Sbjct 80 GVFDR-LAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTNQLKSIPR--GAFDNLKSL 136
Query 509 TILDLSNN 516
T + L NN
Sbjct 137 THIYLFNN 144
Score = 37.4 bits (85), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 33/108 (31%), Positives = 50/108 (46%), Gaps = 2/108 (2%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
T+ L L +N I K++ F L L++ N LS+ +G +L L L LS+N+
Sbjct 38 TDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDNQLSALPIGVFDRLAQLTRLGLSHNQ 97
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AL + D L L L +NQ+K G F + L ++L N
Sbjct 98 FTALPAGVFDKLP--KLTHLVLHTNQLKSIPRGAFDNLKSLTHIYLFN 143
>5wk4_E E Variable lymphocyte receptor 39
Length=201
Score = 58.9 bits (141), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 34/101 (34%), Positives = 50/101 (50%), Gaps = 1/101 (1%)
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L+ L LN+ N +P+ VF L +L + L N LPA VF+ L L L N
Sbjct 61 LTALTFLNVGDNQLSALPIGVFDRLAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTN 120
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWI 661
+ S+ + F ++LT + + NP+DC C I + NWI
Sbjct 121 QLKSIPRGAFD-NLKSLTHIYLFNNPWDCECSDILYLKNWI 160
Score = 56.2 bits (134), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 40/132 (30%), Positives = 62/132 (47%), Gaps = 0/132 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ +C L VP +PT+ L L +NQ+ +L F + LT L+VG N
Sbjct 13 SQCSCRGTTVNCDSRSLASVPAGIPTDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDN 72
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+S L + +L L L L HN+ + L F LT L L +N ++ I F
Sbjct 73 QLSALPIGVFDRLAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTNQLKSIPRGAFDN 132
Query 146 QKNLITLDLSHN 157
K+L + L +N
Sbjct 133 LKSLTHIYLFNN 144
Score = 38.1 bits (87), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 9/128 (7%)
Query 395 TLTNETFVSLAHSPLHI------LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
T N SLA P I L L N+I+K+E F L L L++G N++
Sbjct 20 TTVNCDSRSLASVPAGIPTDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDNQLSALPI 79
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
G R L + + LS+N++ L F +P L L+L LK++ F L++L
Sbjct 80 GVFDR-LAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTNQLKSIPR--GAFDNLKSL 136
Query 509 TILDLSNN 516
T + L NN
Sbjct 137 THIYLFNN 144
Score = 37.4 bits (85), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 33/108 (31%), Positives = 50/108 (46%), Gaps = 2/108 (2%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
T+ L L +N I K++ F L L++ N LS+ +G +L L L LS+N+
Sbjct 38 TDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDNQLSALPIGVFDRLAQLTRLGLSHNQ 97
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AL + D L L L +NQ+K G F + L ++L N
Sbjct 98 FTALPAGVFDKLP--KLTHLVLHTNQLKSIPRGAFDNLKSLTHIYLFN 143
>5wk4_D C Variable lymphocyte receptor 39
Length=201
Score = 58.9 bits (141), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 34/101 (34%), Positives = 50/101 (50%), Gaps = 1/101 (1%)
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L+ L LN+ N +P+ VF L +L + L N LPA VF+ L L L N
Sbjct 61 LTALTFLNVGDNQLSALPIGVFDRLAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTN 120
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWI 661
+ S+ + F ++LT + + NP+DC C I + NWI
Sbjct 121 QLKSIPRGAFD-NLKSLTHIYLFNNPWDCECSDILYLKNWI 160
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 40/136 (29%), Positives = 62/136 (46%), Gaps = 0/136 (0%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLD 81
++C+ +C L VP +PT+ L L +NQ+ +L F + LT L+
Sbjct 9 GGCPSQCSCRGTTVNCDSRSLASVPAGIPTDRQNLWLNNNQITKLEPGVFDSLTALTFLN 68
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNN 141
VG N +S L + +L L L L HN+ + L F LT L L +N ++ I
Sbjct 69 VGDNQLSALPIGVFDRLAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTNQLKSIPRG 128
Query 142 PFVKQKNLITLDLSHN 157
F K+L + L +N
Sbjct 129 AFDNLKSLTHIYLFNN 144
Score = 38.1 bits (87), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 9/128 (7%)
Query 395 TLTNETFVSLAHSPLHI------LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
T N SLA P I L L N+I+K+E F L L L++G N++
Sbjct 20 TTVNCDSRSLASVPAGIPTDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDNQLSALPI 79
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
G R L + + LS+N++ L F +P L L+L LK++ F L++L
Sbjct 80 GVFDR-LAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTNQLKSIPR--GAFDNLKSL 136
Query 509 TILDLSNN 516
T + L NN
Sbjct 137 THIYLFNN 144
Score = 37.0 bits (84), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 33/108 (31%), Positives = 50/108 (46%), Gaps = 2/108 (2%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
T+ L L +N I K++ F L L++ N LS+ +G +L L L LS+N+
Sbjct 38 TDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDNQLSALPIGVFDRLAQLTRLGLSHNQ 97
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AL + D L L L +NQ+K G F + L ++L N
Sbjct 98 FTALPAGVFDKLP--KLTHLVLHTNQLKSIPRGAFDNLKSLTHIYLFN 143
>5wk4_C B Variable lymphocyte receptor 39
Length=201
Score = 58.9 bits (141), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 34/101 (34%), Positives = 50/101 (50%), Gaps = 1/101 (1%)
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L+ L LN+ N +P+ VF L +L + L N LPA VF+ L L L N
Sbjct 61 LTALTFLNVGDNQLSALPIGVFDRLAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTN 120
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWI 661
+ S+ + F ++LT + + NP+DC C I + NWI
Sbjct 121 QLKSIPRGAFD-NLKSLTHIYLFNNPWDCECSDILYLKNWI 160
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 40/136 (29%), Positives = 62/136 (46%), Gaps = 0/136 (0%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLD 81
++C+ +C L VP +PT+ L L +NQ+ +L F + LT L+
Sbjct 9 GGCPSQCSCRGTTVNCDSRSLASVPAGIPTDRQNLWLNNNQITKLEPGVFDSLTALTFLN 68
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNN 141
VG N +S L + +L L L L HN+ + L F LT L L +N ++ I
Sbjct 69 VGDNQLSALPIGVFDRLAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTNQLKSIPRG 128
Query 142 PFVKQKNLITLDLSHN 157
F K+L + L +N
Sbjct 129 AFDNLKSLTHIYLFNN 144
Score = 38.1 bits (87), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 9/128 (7%)
Query 395 TLTNETFVSLAHSPLHI------LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
T N SLA P I L L N+I+K+E F L L L++G N++
Sbjct 20 TTVNCDSRSLASVPAGIPTDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDNQLSALPI 79
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
G R L + + LS+N++ L F +P L L+L LK++ F L++L
Sbjct 80 GVFDR-LAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTNQLKSIPR--GAFDNLKSL 136
Query 509 TILDLSNN 516
T + L NN
Sbjct 137 THIYLFNN 144
Score = 37.0 bits (84), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 33/108 (31%), Positives = 50/108 (46%), Gaps = 2/108 (2%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
T+ L L +N I K++ F L L++ N LS+ +G +L L L LS+N+
Sbjct 38 TDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDNQLSALPIGVFDRLAQLTRLGLSHNQ 97
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AL + D L L L +NQ+K G F + L ++L N
Sbjct 98 FTALPAGVFDKLP--KLTHLVLHTNQLKSIPRGAFDNLKSLTHIYLFN 143
>5wk4_A D Variable lymphocyte receptor 39
Length=201
Score = 58.9 bits (141), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 34/101 (34%), Positives = 50/101 (50%), Gaps = 1/101 (1%)
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L+ L LN+ N +P+ VF L +L + L N LPA VF+ L L L N
Sbjct 61 LTALTFLNVGDNQLSALPIGVFDRLAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTN 120
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWI 661
+ S+ + F ++LT + + NP+DC C I + NWI
Sbjct 121 QLKSIPRGAFD-NLKSLTHIYLFNNPWDCECSDILYLKNWI 160
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 40/136 (29%), Positives = 62/136 (46%), Gaps = 0/136 (0%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLD 81
++C+ +C L VP +PT+ L L +NQ+ +L F + LT L+
Sbjct 9 GGCPSQCSCRGTTVNCDSRSLASVPAGIPTDRQNLWLNNNQITKLEPGVFDSLTALTFLN 68
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNN 141
VG N +S L + +L L L L HN+ + L F LT L L +N ++ I
Sbjct 69 VGDNQLSALPIGVFDRLAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTNQLKSIPRG 128
Query 142 PFVKQKNLITLDLSHN 157
F K+L + L +N
Sbjct 129 AFDNLKSLTHIYLFNN 144
Score = 38.1 bits (87), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 9/128 (7%)
Query 395 TLTNETFVSLAHSPLHI------LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
T N SLA P I L L N+I+K+E F L L L++G N++
Sbjct 20 TTVNCDSRSLASVPAGIPTDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDNQLSALPI 79
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNL 508
G R L + + LS+N++ L F +P L L+L LK++ F L++L
Sbjct 80 GVFDR-LAQLTRLGLSHNQFTALPAGVFDKLPKLTHLVLHTNQLKSIPR--GAFDNLKSL 136
Query 509 TILDLSNN 516
T + L NN
Sbjct 137 THIYLFNN 144
Score = 37.0 bits (84), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 33/108 (31%), Positives = 50/108 (46%), Gaps = 2/108 (2%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
T+ L L +N I K++ F L L++ N LS+ +G +L L L LS+N+
Sbjct 38 TDRQNLWLNNNQITKLEPGVFDSLTALTFLNVGDNQLSALPIGVFDRLAQLTRLGLSHNQ 97
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
AL + D L L L +NQ+K G F + L ++L N
Sbjct 98 FTALPAGVFDKLP--KLTHLVLHTNQLKSIPRGAFDNLKSLTHIYLFN 143
>3g3a_G G Variable lymphocyte receptor VLRB.2D
Length=178
Score = 58.2 bits (139), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 37/106 (35%), Positives = 53/106 (50%), Gaps = 0/106 (0%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C+ S DCS L VP +PT VL L NQ+ +L F R +QLT LD+ N +
Sbjct 15 CSCSGTTVDCSGKSLASVPTGIPTTTQVLYLYDNQITKLEPGVFDRLTQLTRLDLDNNQL 74
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ L + KL L L+L N+L + F +LT + L++N
Sbjct 75 TVLPAGVFDKLTQLTQLSLNDNQLKSIPRGAFDNLKSLTHIWLLNN 120
Score = 55.8 bits (133), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 32/99 (32%), Positives = 50/99 (51%), Gaps = 1/99 (1%)
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+L L N ++ VF L +L +DL N L LPA VF+ L L+L N + S
Sbjct 41 QVLYLYDNQITKLEPGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKS 100
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ + F ++LT + + NP+DC C I + WI++
Sbjct 101 IPRGAFD-NLKSLTHIWLLNNPWDCACSDILYLSRWISQ 138
Score = 32.7 bits (73), Expect = 9.5, Method: Compositional matrix adjust.
Identities = 24/70 (34%), Positives = 33/70 (47%), Gaps = 5/70 (7%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
P F L LT LDL NN + + + + L +L L L N L + P G L
Sbjct 55 PGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKSI-----PRGAFDNL 109
Query 559 KGLSHLHILN 568
K L+H+ +LN
Sbjct 110 KSLTHIWLLN 119
>3g3b_A A variable lymphocyte receptor VLRB.2D
Length=170
Score = 57.8 bits (138), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 36/108 (33%), Positives = 55/108 (51%), Gaps = 0/108 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DCS L VP +PT VL L N++ +L F R +QLT LD+ N
Sbjct 5 SQCSCSGTTVDCSGKSLASVPTGIPTTTQVLYLYDNRITKLEPGVFDRLTQLTRLDLDNN 64
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
++ L + KL L L+L N+L + F +LT + L++N
Sbjct 65 QLTVLPAGVFDKLTQLTQLSLNDNQLKSIPRGAFDNLRSLTHIWLLNN 112
Score = 57.8 bits (138), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 33/99 (33%), Positives = 50/99 (51%), Gaps = 1/99 (1%)
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+L L N ++ VF L +L +DL N L LPA VF+ L L+L N + S
Sbjct 33 QVLYLYDNRITKLEPGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKS 92
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ + F R+LT + + NP+DC C I + WI++
Sbjct 93 IPRGAFD-NLRSLTHIWLLNNPWDCACSDILYLSRWISQ 130
Score = 33.1 bits (74), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 26/83 (31%), Positives = 39/83 (47%), Gaps = 5/83 (6%)
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
T+D S L+S G Q L L +N+I L+ D + L +L+L +NQ+
Sbjct 13 TVDCSGKSLASVPTGIPT---TTQVLYLYDNRITKLEPGVFDRL--TQLTRLDLDNNQLT 67
Query 211 EFSPGCFHAIGRLFGLFLNNVQL 233
G F + +L L LN+ QL
Sbjct 68 VLPAGVFDKLTQLTQLSLNDNQL 90
>3g3b_C C variable lymphocyte receptor VLRB.2D
Length=170
Score = 57.8 bits (138), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 33/99 (33%), Positives = 50/99 (51%), Gaps = 1/99 (1%)
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+L L N ++ VF L +L +DL N L LPA VF+ L L+L N + S
Sbjct 33 QVLYLYDNRITKLEPGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKS 92
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ + F R+LT + + NP+DC C I + WI++
Sbjct 93 IPRGAFD-NLRSLTHIWLLNNPWDCACSDILYLSRWISQ 130
Score = 57.8 bits (138), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 36/108 (33%), Positives = 55/108 (51%), Gaps = 0/108 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DCS L VP +PT VL L N++ +L F R +QLT LD+ N
Sbjct 5 SQCSCSGTTVDCSGKSLASVPTGIPTTTQVLYLYDNRITKLEPGVFDRLTQLTRLDLDNN 64
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
++ L + KL L L+L N+L + F +LT + L++N
Sbjct 65 QLTVLPAGVFDKLTQLTQLSLNDNQLKSIPRGAFDNLRSLTHIWLLNN 112
Score = 33.1 bits (74), Expect = 7.7, Method: Compositional matrix adjust.
Identities = 26/83 (31%), Positives = 39/83 (47%), Gaps = 5/83 (6%)
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
T+D S L+S G Q L L +N+I L+ D + L +L+L +NQ+
Sbjct 13 TVDCSGKSLASVPTGIPT---TTQVLYLYDNRITKLEPGVFDRL--TQLTRLDLDNNQLT 67
Query 211 EFSPGCFHAIGRLFGLFLNNVQL 233
G F + +L L LN+ QL
Sbjct 68 VLPAGVFDKLTQLTQLSLNDNQL 90
Score = 32.7 bits (73), Expect = 10.0, Method: Compositional matrix adjust.
Identities = 23/70 (33%), Positives = 33/70 (47%), Gaps = 5/70 (7%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
P F L LT LDL NN + + + + L +L L L N L + P G L
Sbjct 47 PGVFDRLTQLTRLDLDNNQLTVLPAGVFDKLTQLTQLSLNDNQLKSI-----PRGAFDNL 101
Query 559 KGLSHLHILN 568
+ L+H+ +LN
Sbjct 102 RSLTHIWLLN 111
>6ejx_A D Platelet glycoprotein Ib alpha chain
Length=278
Score = 59.7 bits (143), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 49/158 (31%), Positives = 78/158 (49%), Gaps = 12/158 (8%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
LDLS+NN+ ++ + L L LD+ N L L +PG L GLS L L L+
Sbjct 84 LDLSHNNLKSL-PSLGWALPALTTLDVSFNKLGSL----SPG----VLDGLSQLQELYLQ 134
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+N +P + +LK ++L N L LP+ + + L +L LQ+N + ++ K F
Sbjct 135 NNDLKSLPPGLLLPTTKLKKLNLANNKLRELPSGLLDGLEDLDTLYLQRNWLRTIPKGFF 194
Query 631 GPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
G L + + N + C CE I +F +W+ E N+
Sbjct 195 GTLL--LPFVFLHANSWYCDCE-ILYFRHWLQENANNV 229
Score = 59.7 bits (143), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 91/197 (46%), Gaps = 6/197 (3%)
Query 24 STTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVG 83
S +K T EV +C + KLT +P DLP + +L+L NQL A+ ++ LT L +
Sbjct 7 SISKVTSLLEV-NCENKKLTALPADLPADTGILHLGENQLGTFSTASLVHFTHLTYLYLD 65
Query 84 FNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
++ L+ KL L+ L+L HN L L +A LT L + N + +
Sbjct 66 RCELTSLQTN--GKLIKLENLDLSHNNLKSLPSLGWAL-PALTTLDVSFNKLGSLSPGVL 122
Query 144 VKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
L L L +N L S G + L++L L+NNK++ L S LD + L L
Sbjct 123 DGLSQLQELYLQNNDLKSLPPGLLLPTTKLKKLNLANNKLRELPSGLLDGLED--LDTLY 180
Query 204 LSSNQIKEFSPGCFHAI 220
L N ++ G F +
Sbjct 181 LQRNWLRTIPKGFFGTL 197
Score = 38.1 bits (87), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 51/193 (26%), Positives = 88/193 (46%), Gaps = 17/193 (9%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
++ +L E+ N K+ AL + D+ A++ + L L NQ+ FS L L+L
Sbjct 10 KVTSLLEVNCENKKLTALPA---DLPADTGI--LHLGENQLGTFSTASLVHFTHLTYLYL 64
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
+ +L T ++L NL LS++ L + + LG LT LD+S+N L
Sbjct 65 DRCELTSLQTNGKLIKL-----ENLDLSHNNLKSLPS---LGWALPALTTLDVSFNKLGS 116
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS--LASLPKI 346
+ L QL+ +L+ N+++ L L ++ LNL + ++ S L L +
Sbjct 117 LSPGVLDGLSQLQELYLQNNDLKSLPPGLLLPTTKLKKLNLANNKLRELPSGLLDGLEDL 176
Query 347 DDFSFQ--WLKCL 357
D Q WL+ +
Sbjct 177 DTLYLQRNWLRTI 189
>6ejx_B A Platelet glycoprotein Ib alpha chain
Length=278
Score = 59.7 bits (143), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 49/158 (31%), Positives = 78/158 (49%), Gaps = 12/158 (8%)
Query 511 LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLE 570
LDLS+NN+ ++ + L L LD+ N L L +PG L GLS L L L+
Sbjct 84 LDLSHNNLKSL-PSLGWALPALTTLDVSFNKLGSL----SPG----VLDGLSQLQELYLQ 134
Query 571 SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+N +P + +LK ++L N L LP+ + + L +L LQ+N + ++ K F
Sbjct 135 NNDLKSLPPGLLLPTTKLKKLNLANNKLRELPSGLLDGLEDLDTLYLQRNWLRTIPKGFF 194
Query 631 GPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
G L + + N + C CE I +F +W+ E N+
Sbjct 195 GTLL--LPFVFLHANSWYCDCE-ILYFRHWLQENANNV 229
Score = 59.7 bits (143), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 60/197 (30%), Positives = 91/197 (46%), Gaps = 6/197 (3%)
Query 24 STTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVG 83
S +K T EV +C + KLT +P DLP + +L+L NQL A+ ++ LT L +
Sbjct 7 SISKVTSLLEV-NCENKKLTALPADLPADTGILHLGENQLGTFSTASLVHFTHLTYLYLD 65
Query 84 FNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
++ L+ KL L+ L+L HN L L +A LT L + N + +
Sbjct 66 RCELTSLQTN--GKLIKLENLDLSHNNLKSLPSLGWAL-PALTTLDVSFNKLGSLSPGVL 122
Query 144 VKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
L L L +N L S G + L++L L+NNK++ L S LD + L L
Sbjct 123 DGLSQLQELYLQNNDLKSLPPGLLLPTTKLKKLNLANNKLRELPSGLLDGLED--LDTLY 180
Query 204 LSSNQIKEFSPGCFHAI 220
L N ++ G F +
Sbjct 181 LQRNWLRTIPKGFFGTL 197
Score = 38.1 bits (87), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 51/193 (26%), Positives = 88/193 (46%), Gaps = 17/193 (9%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
++ +L E+ N K+ AL + D+ A++ + L L NQ+ FS L L+L
Sbjct 10 KVTSLLEVNCENKKLTALPA---DLPADTGI--LHLGENQLGTFSTASLVHFTHLTYLYL 64
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
+ +L T ++L NL LS++ L + + LG LT LD+S+N L
Sbjct 65 DRCELTSLQTNGKLIKL-----ENLDLSHNNLKSLPS---LGWALPALTTLDVSFNKLGS 116
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS--LASLPKI 346
+ L QL+ +L+ N+++ L L ++ LNL + ++ S L L +
Sbjct 117 LSPGVLDGLSQLQELYLQNNDLKSLPPGLLLPTTKLKKLNLANNKLRELPSGLLDGLEDL 176
Query 347 DDFSFQ--WLKCL 357
D Q WL+ +
Sbjct 177 DTLYLQRNWLRTI 189
>1o77_D D TOLL-LIKE RECEPTOR 2
Length=146
Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 38/146 (26%), Positives = 73/146 (50%), Gaps = 4/146 (3%)
Query 756 YAAYIIHAYKDKDWVWEHFSSMEKED--QSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
Y A++ ++ +D WV E+ E E+ K CL +RDF G + ++ I++SI++S K
Sbjct 3 YDAFVSYSERDAYWV-ENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKT 61
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
+FV++ + +K K +++ + + + IL+ LE I + C R + +
Sbjct 62 VFVLSENFVKSEWSK-YELDFSHFRLFXXXXXAAILILLEPIEKKAIPQRFCKLRKIMNT 120
Query 874 HCILNWPVQKERIGAFRHKLQVALGS 899
L WP+ + + F L+ A+ S
Sbjct 121 KTYLEWPMDEAQREGFWVNLRAAIKS 146
>1o77_A A TOLL-LIKE RECEPTOR 2
Length=146
Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 38/146 (26%), Positives = 73/146 (50%), Gaps = 4/146 (3%)
Query 756 YAAYIIHAYKDKDWVWEHFSSMEKED--QSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
Y A++ ++ +D WV E+ E E+ K CL +RDF G + ++ I++SI++S K
Sbjct 3 YDAFVSYSERDAYWV-ENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSHKT 61
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
+FV++ + +K K +++ + + + IL+ LE I + C R + +
Sbjct 62 VFVLSENFVKSEWSK-YELDFSHFRLFXXXXXAAILILLEPIEKKAIPQRFCKLRKIMNT 120
Query 874 HCILNWPVQKERIGAFRHKLQVALGS 899
L WP+ + + F L+ A+ S
Sbjct 121 KTYLEWPMDEAQREGFWVNLRAAIKS 146
>7la7_A A variable lymphocyte receptor O6
Length=184
Score = 57.8 bits (138), Expect = 4e-08, Method: Composition-based stats.
Identities = 34/108 (31%), Positives = 54/108 (50%), Gaps = 0/108 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S +C + VP +P L L++NQL +L F +QLT+L + N
Sbjct 16 SQCSCSGTDVNCDGARXASVPAAIPITTQRLWLSNNQLTKLDPGVFDSLTQLTTLYLSNN 75
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
++ L + KL LK L L N+L + D FA +LT + L +N
Sbjct 76 QLTALPAGVFDKLTQLKELGLDQNQLKSIPDGAFARLPSLTHVWLHTN 123
Score = 56.2 bits (134), Expect = 1e-07, Method: Composition-based stats.
Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 2/102 (2%)
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
L L +N ++ VF L +L + L N L LPA VF+ LK L L +N + S+
Sbjct 46 LWLSNNQLTKLDPGVFDSLTQLTTLYLSNNQLTALPAGVFDKLTQLKELGLDQNQLKSIP 105
Query 627 KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
F +LT + + NP+DC C I + W+ + H++I
Sbjct 106 DGAFA-RLPSLTHVWLHTNPWDCQCTDILYLSGWVAQ-HSSI 145
Score = 37.4 bits (85), Expect = 0.28, Method: Composition-based stats.
Identities = 30/111 (27%), Positives = 46/111 (41%), Gaps = 29/111 (26%)
Query 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSN 257
+ ++L LS+NQ+ + PG F ++ T + L LSN
Sbjct 42 TTQRLWLSNNQLTKLDPGVFDSL---------------------------TQLTTLYLSN 74
Query 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
+QL+ F K T L L L N L + + +FA LP L + +L N
Sbjct 75 NQLTALPAGVF--DKLTQLKELGLDQNQLKSIPDGAFARLPSLTHVWLHTN 123
Score = 37.0 bits (84), Expect = 0.42, Method: Composition-based stats.
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 2/76 (3%)
Query 154 LSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LS+N L+ G L L L LSNN++ AL + D + LK+L L NQ+K
Sbjct 48 LSNNQLTKLDPGVFDSLTQLTTLYLSNNQLTALPAGVFDKL--TQLKELGLDQNQLKSIP 105
Query 214 PGCFHAIGRLFGLFLN 229
G F + L ++L+
Sbjct 106 DGAFARLPSLTHVWLH 121
>3rg1_C I CD180 molecule
Length=612
Score = 60.8 bits (146), Expect = 4e-08, Method: Compositional matrix adjust.
Identities = 81/350 (23%), Positives = 153/350 (44%), Gaps = 23/350 (7%)
Query 27 KCTV--SHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGF 84
KCT + +C +L L ++PD LP VL + N L + F+R L LD+
Sbjct 6 KCTEKEGNRTYNCENLGLREIPDTLPNTTEVLEFSFNFLPTIQNTTFSRLINLIFLDLTR 65
Query 85 NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV 144
I+ + + Q L + L N L +++ + L L L I ++ P
Sbjct 66 CQINWVHEDTFQSHHQLNTIVLTGNPLIFMAETSLTGPKFLKHLFLTQTGISNLEFIPVH 125
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
+NL +L L N +SS L +NL+ L NN I + ++ + ++ L
Sbjct 126 NLENLESLHLGSNHISSINLPENFPTQNLKVLDFQNNAIHYISRKDTNSLEQATNLSLNF 185
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLE-LANTSIRNL---SLSNSQL 260
+ N IK PG F I ++F +++ G SL + + L N+++++L + ++
Sbjct 186 NGNDIKGIEPGAF--ISKIF----QSLKFGGSLNLFIIFKGLQNSTLQSLWLGTFEDTDD 239
Query 261 STTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHG 320
++ TF GL ++ ++L + + + + +F +++ L ++ L S + G
Sbjct 240 QYLTSATFEGLCDMSVESINLQKHRFSDLSSSTFRCFTRVQELDLTAAHLNGLPS-GIEG 298
Query 321 LFNVRYLNLKRSFTKQ--SISLASLPKIDDFSFQ--------WLKCLEHL 360
+ +++ L L + Q I+ AS P + D + +CLE L
Sbjct 299 MNSLKKLVLNANSFDQLCQINAASFPSLRDLYIKGNMRKLDLGTRCLEKL 348
>4xgo_B B Anopheles Plasmodium-responsive Leucine-rich repeat
protein 1B
Length=356
Score = 59.7 bits (143), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 76/277 (27%), Positives = 123/277 (44%), Gaps = 36/277 (13%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
+ VLNL Q+ + F + L + FN I L P + Q +P+L VL L N+LS
Sbjct 25 VEVLNLNGLQIEEIDTNAFAYAHTIQKLYMRFNVIRYLPPHVFQNVPLLTVLMLDRNDLS 84
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL-- 170
L F LT + + +N++++I+++ F L L LS N L+ L L
Sbjct 85 SLPPGIFHNTPKLTMMSMSNNNLERIEDDTFQATTALQNLQLSSNRLTHVDLALIPSLFH 144
Query 171 ENLQELLLSNNKIQALKSEELDIFANS----------SLKKLELSSNQIKEFS-----PG 215
N+ LLS I + EELD N+ L L+L N + + + PG
Sbjct 145 VNVSYNLLSTLAI-PIAVEELDASHNTINVVRGPVNVELTILKLQHNNLTDTAWLLNYPG 203
Query 216 CFHAIGRLFGLFLNNVQLGPSLTEKLCLE--LANTSIRNLSLSNSQLSTTSNTTFLGLKW 273
L +V L + EK+ + + + L +SN++L F
Sbjct 204 ------------LVDVDLSYNQLEKITYQHFVKMQRLERLYVSNNRLVALD---FXXXXX 248
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNI 310
L +LDLS+N+L V ++ A +L+Y +L++N+I
Sbjct 249 XTLKVLDLSHNHLMWVEHNQ-AQFDKLQYLYLDHNSI 284
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 58/217 (27%), Positives = 95/217 (44%), Gaps = 27/217 (12%)
Query 433 LEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVAL 492
+EVL+L +I +E+ + I ++Y+ +N L + F VP L LML R L
Sbjct 25 VEVLNLNGLQI-EEIDTNAFAYAHTIQKLYMRFNVIRYLPPHVFQNVPLLTVLMLDRNDL 83
Query 493 KNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPG 552
++ P F LT++ +SNNN+ I DD + L+ L L N L +
Sbjct 84 SSL--PPGIFHNTPKLTMMSMSNNNLERIEDDTFQATTALQNLQLSSNRLTHV------- 134
Query 553 GPIYFLKGLSHLHI-LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVS 611
+ + L H+++ NL S IP+ V + +D N +N + V V
Sbjct 135 -DLALIPSLFHVNVSYNLLSTL--AIPIAVEE-------LDASHNTINVVRGPV---NVE 181
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
L L LQ N +T + P L ++D+ +N +
Sbjct 182 LTILKLQHNNLTDTAWLLNYPG---LVDVDLSYNQLE 215
Score = 39.3 bits (90), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 58/271 (21%), Positives = 117/271 (43%), Gaps = 39/271 (14%)
Query 289 VGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS---------------F 333
+ ++FA+ ++ ++ +N I++L H + + L L R+
Sbjct 38 IDTNAFAYAHTIQKLYMRFNVIRYLPPHVFQNVPLLTVLMLDRNDLSSLPPGIFHNTPKL 97
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
T S+S +L +I+D +FQ L++L + N + + + L ++ S+ L
Sbjct 98 TMMSMSNNNLERIEDDTFQATTALQNLQLSSNRLTHVDLALIPSLFHVNV-----SYNLL 152
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEW- 452
TL V + + +N+ + ++ +E L +L L N LT W
Sbjct 153 STLAIPIAVEELDASHNTINVVRGPVN-VE---------LTILKLQHN----NLTDTAWL 198
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
+ ++ LSYN+ ++T F + L+RL + L +D L+ +LD
Sbjct 199 LNYPGLVDVDLSYNQLEKITYQHFVKMQRLERLYVSNNRLVALDFXXXXXXTLK---VLD 255
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
LS+N++ + + + +KL+ L L HN++
Sbjct 256 LSHNHLMWVEHNQAQ-FDKLQYLYLDHNSIV 285
Score = 37.4 bits (85), Expect = 0.64, Method: Compositional matrix adjust.
Identities = 43/150 (29%), Positives = 66/150 (44%), Gaps = 4/150 (3%)
Query 24 STTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVG 83
ST ++ E D SH + V + +T+L L HN L A Y L +D+
Sbjct 153 STLAIPIAVEELDASHNTINVVRGPVNVELTILKLQHNNLT--DTAWLLNYPGLVDVDLS 210
Query 84 FNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
+N + K+ + K+ L+ L + +N L L D L L L N + +++N
Sbjct 211 YNQLEKITYQHFVKMQRLERLYVSNNRLVAL-DFXXXXXXTLKVLDLSHNHLMWVEHNQA 269
Query 144 VKQKNLITLDLSHNGLSSTKLGTQVQLENL 173
K L L L HN + + KL T L+NL
Sbjct 270 QFDK-LQYLYLDHNSIVTFKLSTSHTLKNL 298
>6wml_C C Toll-like receptor 8
Length=811
Score = 60.8 bits (146), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 172/710 (24%), Positives = 273/710 (38%), Gaps = 155/710 (22%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + +T L+L+ N + + +F LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KEGISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLM 486
F L + L+L N Q L+G E+ + ++ KYL LT N
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNN------------ 518
Query 487 LRRVALKNVDSSPSPFQPLRNLTILDLSNNN----IANIND--DMLEGLEKLEILDLQHN 540
R+ N S L +L +LDLS N+ IA + + ++ L++L+L HN
Sbjct 519 --RLDFDNA----SALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHN 572
Query 541 NLARLWKHANPGGPIYFLKGLSHL----HILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
N+ L N K L L + L++ N D + +FK L L +DL LN
Sbjct 573 NIYTLTDKYNLES-----KSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLN 627
Query 597 NLNTLPASVF-NNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L +P F N SL L++ N++ + F L LD+R N
Sbjct 628 RLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQ-QFPRLELLDLRGN 676
Score = 40.8 bits (94), Expect = 0.070, Method: Compositional matrix adjust.
Identities = 63/218 (29%), Positives = 98/218 (45%), Gaps = 38/218 (17%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L++ N I I N F L ++ L+LS + ++ + L+ F ++ H + L+LT N++
Sbjct 464 LDLSLNSIFFIGPNQFENLPDIACLNLSAN-SNAQVLSGTEFSAIPH--VKYLDLTNNRL 520
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTG-----QEWRGLENIFEIYLSYNKYLQLTRN 474
+ A + L LEVLDL N + G + + N+ + LS+N LT
Sbjct 521 DFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDK 580
Query 475 SFALVPSLQRLML---RRVALKNVDSSP--SPFQPLRNLTILDLSNNNIANI-------- 521
SL L+ R L N D + S F+ L+NLT LDLS N + +I
Sbjct 581 YNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNL 640
Query 522 ---------NDDML--------EGLEKLEILDLQHNNL 542
ND+ML + +LE+LDL+ N L
Sbjct 641 PASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKL 678
>6wml_D D Toll-like receptor 8
Length=811
Score = 60.8 bits (146), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 188/802 (23%), Positives = 290/802 (36%), Gaps = 186/802 (23%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS----- 88
+A+CS+ +L +VP + T L+L+ N + + LT +++ N
Sbjct 24 IAECSNRRLQEVPQTVGKXXTELDLSDNFITHITNXXXXXXXXLTKINLNHNPNXXXXXX 83
Query 89 ---------KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
+ L L+ L L+ N+L Q+ +LTEL L+ N+I I
Sbjct 84 XXXXXXXGLNITDGAFLNLKNLRELLLEDNQLPQIPS---GLPESLTELSLIQNNIYNIT 140
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN--------------------------- 172
+ NL L L+ N + K+ + +E+
Sbjct 141 KXXISRLINLKNLYLAWNCYFN-KVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLP 199
Query 173 --LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L++L LSN +I+ + E+ N +L L+LS N P CF+A
Sbjct 200 SSLRKLFLSNTQIKYISEEDFKGLINLTL--LDLSGN-----CPRCFNAPFPCVP----- 247
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL--NV 288
G S+ T +R L+LS++ L + F + +L +LDL +N L +
Sbjct 248 CDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMP--HLKVLDLEFNYLVGEI 305
Query 289 VGNDSFAWLPQLEYFFLEYNNI-----QHL-FSHSLHGLFNVRYLNLKRSFTKQSISLAS 342
LP+LE L +N I QH+ S + L ++R L+L R + Q +
Sbjct 306 ASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHL-RGYVFQEL---- 360
Query 343 LPKIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--------- 392
+ DDF L L +N+ N I I +F NL+ + LS + S
Sbjct 361 --REDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLXXXXXXX 418
Query 393 ----------LRTLTNETFVSLAHS-------PL---------HILNLTKNKISKIESDA 426
F HS PL L+L+ N I I +
Sbjct 419 XXXXXXXXXXXXXXXXXXFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQ 478
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN--SFALVPSLQR 484
F L + L+L N Q L+G E+ + ++ KYL LT N F +L
Sbjct 479 FENLPDIACLNLSANSNAQVLSGTEFSAIPHV--------KYLDLTNNRLDFDNASALTE 530
Query 485 LMLRRV----------ALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKLE 533
L V + V Q NL +L+LS+NNI + D LE +E
Sbjct 531 LSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVE 590
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF----KDLFELK 589
++ N L LW + I KGL +L L+L N IP E F L EL
Sbjct 591 LV-FSGNRLDILWNDDD-NRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELH 648
Query 590 IID---------------------------------------------LGLNNLNTLPAS 604
I D L N ++ LP+
Sbjct 649 INDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSX 708
Query 605 VFNNQVSLKSLNLQKNLITSVEKKV-FGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
SLK L+L NL+ ++ K L+ L++ NPF+CTC+ +
Sbjct 709 XXXXVSSLKHLDLSSNLLKTINKSAXXXXXXXKLSMLELHGNPFECTCDIGDFRRXXXXX 768
Query 664 THTNIPELSSHYLCNTPPHYHG 685
+ IP L +C +P G
Sbjct 769 LNVKIPRLVD-VICASPXXQRG 789
>8h24_A A Leucine-rich alpha-2-glycoprotein
Length=347
Score = 59.3 bits (142), Expect = 6e-08, Method: Compositional matrix adjust.
Identities = 74/260 (28%), Positives = 109/260 (42%), Gaps = 37/260 (14%)
Query 43 TQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLK 102
++P LP + L + L LPA S+L L + N + L PE + +P L+
Sbjct 60 AEIPGYLPADTVHLAVEFFNLTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLR 119
Query 103 VLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSST 162
VL+L N L+ L F L L L N ++ ++ + K L LDLS N
Sbjct 120 VLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGN----- 174
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGR 222
+L L LL+N + L+ L+L NQ++ P +
Sbjct 175 ------RLRKLPPGLLANFTL---------------LRTLDLGENQLETLPPDLLRGPLQ 213
Query 223 LFGLFL--NNVQ-LGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTML 279
L L L N +Q LG L L +R L L+ ++L+ + F GL+ L ML
Sbjct 214 LERLHLEGNKLQVLGKDLL------LPQPDLRYLFLNGNKLARVAAGAFQGLR--QLDML 265
Query 280 DLSYNNLNVVGNDSFAWLPQ 299
DLS N+L V +A L Q
Sbjct 266 DLSNNSLASVPEGLWASLGQ 285
Score = 58.2 bits (139), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 63/236 (27%), Positives = 93/236 (39%), Gaps = 39/236 (17%)
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L+ L + L ELHL SN ++ + L LDL+ N L+ G
Sbjct 80 LTHLPANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQAS 139
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
L L+L N+++ L+ L +L L+LS N++++ PG
Sbjct 140 ATLDTLVLKENQLEVLEVSWLHGL--KALGHLDLSGNRLRKLPPGL-------------- 183
Query 231 VQLGPSLTEKLCLELAN-TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVV 289
LAN T +R L L +QL T G L L L N L V+
Sbjct 184 --------------LANFTLLRTLDLGENQLETLPPDLLRGP--LQLERLHLEGNKLQVL 227
Query 290 GNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
G D P L Y FL N + + + + GL + L+L + SLAS+P+
Sbjct 228 GKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNN------SLASVPE 277
Score = 54.7 bits (130), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 48/181 (27%), Positives = 80/181 (44%), Gaps = 30/181 (17%)
Query 482 LQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNN 541
LQ L L L+++ SP +P+ L +LDL+ N + + + + L+ L L+ N
Sbjct 94 LQELHLSSNGLESL--SPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQ 151
Query 542 LARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTL 601
L L + +L GL L L+L N ++P + + L+ +DLG N L TL
Sbjct 152 LEVL--------EVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETL 203
Query 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGP--------------------AFRNLTELD 641
P + + L+ L+L+ N + + K + P AF+ L +LD
Sbjct 204 PPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLD 263
Query 642 M 642
M
Sbjct 264 M 264
Score = 51.2 bits (121), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 57/228 (25%), Positives = 101/228 (44%), Gaps = 24/228 (11%)
Query 302 YFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLN 361
+ +E+ N+ HL ++ L G ++ L+L + ++ S ++L+ + L
Sbjct 72 HLAVEFFNLTHLPANLLQGASKLQELHLSSN------------GLESLSPEFLRPVPQLR 119
Query 362 MED---NDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+ D N + G+ +F L L L N L +L H L+L+ N
Sbjct 120 VLDLTRNALTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGH-----LDLSGN 174
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ K+ + L LDLG N++ + L RG + ++L NK L ++
Sbjct 175 RLRKLPPGLLANFTLLRTLDLGENQL-ETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLL 233
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
P L+ L L L V + FQ LR L +LDLSNN++A++ + +
Sbjct 234 PQPDLRYLFLNGNKLARVAAGA--FQGLRQLDMLDLSNNSLASVPEGL 279
Score = 46.2 bits (108), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 24/73 (33%), Positives = 41/73 (56%), Gaps = 0/73 (0%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P L+G S L L+L SNG + + E + + +L+++DL N L LP +F +L
Sbjct 84 PANLLQGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLD 143
Query 614 SLNLQKNLITSVE 626
+L L++N + +E
Sbjct 144 TLVLKENQLEVLE 156
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 59/234 (25%), Positives = 92/234 (39%), Gaps = 33/234 (14%)
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
+G + E++LS N L+ VP L+ L L R AL + P FQ L L
Sbjct 89 QGASKLQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGL--PPGLFQASATLDTLV 146
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGG------------------- 553
L N + + L GL+ L LDL N L +L P G
Sbjct 147 LKENQLEVLEVSWLHGLKALGHLDLSGNRLRKL-----PPGLLANFTLLRTLDLGENQLE 201
Query 554 --PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVS 611
P L+G L L+LE N + ++ +L+ + L N L + A F
Sbjct 202 TLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQ 261
Query 612 LKSLNLQKNLITSVEKKVFG----PAFRNLTELDMRFNPFDCTCESIAWFVNWI 661
L L+L N + SV + ++ P + D+ NP+ C ++++ W+
Sbjct 262 LDMLDLSNNSLASVPEGLWASLGQPNWDMRDGFDISGNPWICD-QNLSDLYRWL 314
Score = 41.2 bits (95), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 54/211 (26%), Positives = 93/211 (44%), Gaps = 35/211 (17%)
Query 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
HL +E ++ + +N+ G L+ L LS++ L +L+ E + L +L+LT+N
Sbjct 72 HLAVEFFNLTHLPANLLQGASKLQELHLSSN--GLESLSPEFLRPVPQ--LRVLDLTRNA 127
Query 419 ISKIESDAFSWLG----------HLEVLDL----GLNEIGQ-ELTGQEWRGLENIFEIYL 463
++ + F LEVL++ GL +G +L+G R L
Sbjct 128 LTGLPPGLFQASATLDTLVLKENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANF 187
Query 464 SYNKYLQLTRNSFALVPS--------LQRLMLRRVALKNVDSS---PSPFQPLRNLTILD 512
+ + L L N +P L+RL L L+ + P P +L L
Sbjct 188 TLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNKLQVLGKDLLLPQP-----DLRYLF 242
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
L+ N +A + +GL +L++LDL +N+LA
Sbjct 243 LNGNKLARVAAGAFQGLRQLDMLDLSNNSLA 273
>4z5w_A A Phytosulfokine receptor 1
Length=642
Score = 60.1 bits (144), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 76/241 (32%), Positives = 108/241 (45%), Gaps = 25/241 (10%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
+ VLNLTHN L AA+ S L LD+ N S L P L LP L+VLN+ N
Sbjct 89 LKVLNLTHNSLSGSIAASLLNLSNLEVLDLSSNDFSGLFPSLIN-LPSLRVLNVYENSFH 147
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT---LDLSHNGLSSTKLGTQVQ 169
L + C NL + + ++ + V N + L L+ N LS + Q
Sbjct 148 GLIPAS--LCNNLPRIREIDLAMNYFDGSIPVGIGNCSSVEYLGLASNNLSGSIPQELFQ 205
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLF----- 224
L NL L L NN++ S +L +N L +L++SSN+ P F + +L+
Sbjct 206 LSNLSVLALQNNRLSGALSSKLGKLSN--LGRLDISSNKFSGKIPDVFLELNKLWYFSAQ 263
Query 225 -GLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
LF N ++ SL+ + L S+RN +LS S TNLT LDL+
Sbjct 264 SNLF--NGEMPRSLSNSRSISL--LSLRNNTLSGQIYLNCS-------AMTNLTSLDLAS 312
Query 284 N 284
N
Sbjct 313 N 313
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 142/569 (25%), Positives = 218/569 (38%), Gaps = 162/569 (28%)
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSI 135
++ L++G +S E KL LKVLNL HN LS + +NL L L SN
Sbjct 64 RVVELELGRRKLSGKLSESVAKLDQLKVLNLTHNSLSGSIAASLLNLSNLEVLDLSSNDF 123
Query 136 QKIKNNPFVKQKNLITLDL------SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSE 189
+ F NL +L + S +GL L L ++E+ L+ N S
Sbjct 124 SGL----FPSLINLPSLRVLNVYENSFHGLIPASLCN--NLPRIREIDLAMNYFDG--SI 175
Query 190 ELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS 249
+ I SS++ L L+SN + P + L L L N +L +L+ KL
Sbjct 176 PVGIGNCSSVEYLGLASNNLSGSIPQELFQLSNLSVLALQNNRLSGALSSKLG------- 228
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
K +NL LD+S N + D F L +L YF + N
Sbjct 229 ----------------------KLSNLGRLDISSNKFSGKIPDVFLELNKLWYFSAQSN- 265
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFT-KQSISLASLPKIDDFSFQ-WLKCLEHLNMEDNDI 367
LFN + RS + +SISL SL + + S Q +L C N+ D
Sbjct 266 -----------LFNGE---MPRSLSNSRSISLLSL-RNNTLSGQIYLNCSAMTNLTSLD- 309
Query 368 PGIKSNMFTGLI----------------NLKYLS-LSNSFTSLRTLTNETFVS------- 403
+ SN F+G I +K+++ + SF + ++LT+ +F +
Sbjct 310 --LASNSFSGSIPSNLPNCLRLKTINFAKIKFIAQIPESFKNFQSLTSLSFSNSSIQNIS 367
Query 404 -----LAH-----SPLHILNLTKNKISKIESDAF------------------SWLGH--- 432
L H + + LN K ++ + S F WL +
Sbjct 368 SALEILQHCQNLKTLVLTLNFQKEELPSVPSLQFKNLKVLIIASCQLRGTVPQWLSNSPS 427
Query 433 LEVLDLGLNEIGQELTGQEWRG-LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVA 491
L++LDL N++ + W G L ++F + LS N ++ +S SLQ L+ +
Sbjct 428 LQLLDLSWNQLSGTIP--PWLGSLNSLFYLDLSNNTFIGEIPHSLT---SLQSLVSKXXX 482
Query 492 LKNVD------------------SSPSPFQP-------------------LRNLTILDLS 514
+ PS F P LR L +L+L
Sbjct 483 XXXXXPDFPFFKKXXXXXXGLQYNQPSSFPPMIDLSYNSLNGSIWPEFGDLRQLHVLNLK 542
Query 515 NNNIANINDDMLEGLEKLEILDLQHNNLA 543
NNN++ L G+ LE+LDL HNNL+
Sbjct 543 NNNLSGNIPANLSGMTSLEVLDLSHNNLS 571
Score = 34.3 bits (77), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 85/323 (26%), Positives = 145/323 (45%), Gaps = 30/323 (9%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
I++L+L +N L N + + LTSLD+ N+ S P LK +N +
Sbjct 281 ISLLSLRNNTLSGQIYLNCSAMTNLTSLDLASNSFSGSIPSNLPNCLRLKTINFAKIKFI 340
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHNGLSSTKLGT--QV 168
++F +LT L ++SIQ I + + Q +NL TL L+ N +L + +
Sbjct 341 AQIPESFKNFQSLTSLSFSNSSIQNISSALEILQHCQNLKTLVLTLN-FQKEELPSVPSL 399
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
Q +NL+ L++++ +++ + L + SL+ L+LS NQ+ P ++ LF L L
Sbjct 400 QFKNLKVLIIASCQLRGTVPQWLS--NSPSLQLLDLSWNQLSGTIPPWLGSLNSLFYLDL 457
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF----------LGLKWTNLT- 277
+N + L TS+++L +S F GL++ +
Sbjct 458 SNNTFIGEIPHSL------TSLQSL-VSKXXXXXXXXPDFPFFKKXXXXXXGLQYNQPSS 510
Query 278 ---MLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
M+DLSYN+LN F L QL L+ NN+ +L G+ ++ L+L +
Sbjct 511 FPPMIDLSYNSLNGSIWPEFGDLRQLHVLNLKNNNLSGNIPANLSGMTSLEVLDLSHNNL 570
Query 335 KQSI--SLASLPKIDDFSFQWLK 355
+I SL L + FS + K
Sbjct 571 SGNIPPSLVKLSFLSTFSVAYNK 593
>4z61_B B Phytosulfokine receptor 1
Length=642
Score = 60.1 bits (144), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 76/241 (32%), Positives = 108/241 (45%), Gaps = 25/241 (10%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
+ VLNLTHN L AA+ S L LD+ N S L P L LP L+VLN+ N
Sbjct 89 LKVLNLTHNSLSGSIAASLLNLSNLEVLDLSSNDFSGLFPSLI-NLPSLRVLNVYENSFH 147
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT---LDLSHNGLSSTKLGTQVQ 169
L + C NL + + ++ + V N + L L+ N LS + Q
Sbjct 148 GLIPAS--LCNNLPRIREIDLAMNYFDGSIPVGIGNCSSVEYLGLASNNLSGSIPQELFQ 205
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLF----- 224
L NL L L NN++ S +L +N L +L++SSN+ P F + +L+
Sbjct 206 LSNLSVLALQNNRLSGALSSKLGKLSN--LGRLDISSNKFSGKIPDVFLELNKLWYFSAQ 263
Query 225 -GLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
LF N ++ SL+ + L S+RN +LS S TNLT LDL+
Sbjct 264 SNLF--NGEMPRSLSNSRSISL--LSLRNNTLSGQIYLNCS-------AMTNLTSLDLAS 312
Query 284 N 284
N
Sbjct 313 N 313
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 142/569 (25%), Positives = 218/569 (38%), Gaps = 162/569 (28%)
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSI 135
++ L++G +S E KL LKVLNL HN LS + +NL L L SN
Sbjct 64 RVVELELGRRKLSGKLSESVAKLDQLKVLNLTHNSLSGSIAASLLNLSNLEVLDLSSNDF 123
Query 136 QKIKNNPFVKQKNLITLDL------SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSE 189
+ F NL +L + S +GL L L ++E+ L+ N S
Sbjct 124 SGL----FPSLINLPSLRVLNVYENSFHGLIPASLCN--NLPRIREIDLAMNYFDG--SI 175
Query 190 ELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS 249
+ I SS++ L L+SN + P + L L L N +L +L+ KL
Sbjct 176 PVGIGNCSSVEYLGLASNNLSGSIPQELFQLSNLSVLALQNNRLSGALSSKLG------- 228
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
K +NL LD+S N + D F L +L YF + N
Sbjct 229 ----------------------KLSNLGRLDISSNKFSGKIPDVFLELNKLWYFSAQSN- 265
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFT-KQSISLASLPKIDDFSFQ-WLKCLEHLNMEDNDI 367
LFN + RS + +SISL SL + + S Q +L C N+ D
Sbjct 266 -----------LFNGE---MPRSLSNSRSISLLSL-RNNTLSGQIYLNCSAMTNLTSLD- 309
Query 368 PGIKSNMFTGLI----------------NLKYLS-LSNSFTSLRTLTNETFVS------- 403
+ SN F+G I +K+++ + SF + ++LT+ +F +
Sbjct 310 --LASNSFSGSIPSNLPNCLRLKTINFAKIKFIAQIPESFKNFQSLTSLSFSNSSIQNIS 367
Query 404 -----LAH-----SPLHILNLTKNKISKIESDAF------------------SWLGH--- 432
L H + + LN K ++ + S F WL +
Sbjct 368 SALEILQHCQNLKTLVLTLNFQKEELPSVPSLQFKNLKVLIIASCQLRGTVPQWLSNSPS 427
Query 433 LEVLDLGLNEIGQELTGQEWRG-LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVA 491
L++LDL N++ + W G L ++F + LS N ++ +S SLQ L+ +
Sbjct 428 LQLLDLSWNQLSGTIP--PWLGSLNSLFYLDLSNNTFIGEIPHSLT---SLQSLVSKXXX 482
Query 492 LKNVD------------------SSPSPFQP-------------------LRNLTILDLS 514
+ PS F P LR L +L+L
Sbjct 483 XXXXXPDFPFFKKXXXXXXGLQYNQPSSFPPMIDLSYNSLNGSIWPEFGDLRQLHVLNLK 542
Query 515 NNNIANINDDMLEGLEKLEILDLQHNNLA 543
NNN++ L G+ LE+LDL HNNL+
Sbjct 543 NNNLSGNIPANLSGMTSLEVLDLSHNNLS 571
Score = 34.3 bits (77), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 85/323 (26%), Positives = 145/323 (45%), Gaps = 30/323 (9%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
I++L+L +N L N + + LTSLD+ N+ S P LK +N +
Sbjct 281 ISLLSLRNNTLSGQIYLNCSAMTNLTSLDLASNSFSGSIPSNLPNCLRLKTINFAKIKFI 340
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ--KNLITLDLSHNGLSSTKLGT--QV 168
++F +LT L ++SIQ I + + Q +NL TL L+ N +L + +
Sbjct 341 AQIPESFKNFQSLTSLSFSNSSIQNISSALEILQHCQNLKTLVLTLN-FQKEELPSVPSL 399
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
Q +NL+ L++++ +++ + L + SL+ L+LS NQ+ P ++ LF L L
Sbjct 400 QFKNLKVLIIASCQLRGTVPQWLS--NSPSLQLLDLSWNQLSGTIPPWLGSLNSLFYLDL 457
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF----------LGLKWTNLT- 277
+N + L TS+++L +S F GL++ +
Sbjct 458 SNNTFIGEIPHSL------TSLQSL-VSKXXXXXXXXPDFPFFKKXXXXXXGLQYNQPSS 510
Query 278 ---MLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
M+DLSYN+LN F L QL L+ NN+ +L G+ ++ L+L +
Sbjct 511 FPPMIDLSYNSLNGSIWPEFGDLRQLHVLNLKNNNLSGNIPANLSGMTSLEVLDLSHNNL 570
Query 335 KQSI--SLASLPKIDDFSFQWLK 355
+I SL L + FS + K
Sbjct 571 SGNIPPSLVKLSFLSTFSVAYNK 593
>4z61_A A Phytosulfokine receptor 1
Length=642
Score = 60.1 bits (144), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 74/236 (31%), Positives = 110/236 (47%), Gaps = 15/236 (6%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
+ VLNLTHN L AA+ S L LD+ N S L P L LP L+VLN+ N
Sbjct 89 LKVLNLTHNSLSGSIAASLLNLSNLEVLDLSSNDFSGLFPSLI-NLPSLRVLNVYENSFH 147
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT---LDLSHNGLSSTKLGTQVQ 169
L + C NL + + ++ + V N + L L+ N LS + Q
Sbjct 148 GLIPAS--LCNNLPRIREIDLAMNYFDGSIPVGIGNCSSVEYLGLASNNLSGSIPQELFQ 205
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L NL L L NN++ S +L +N L +L++SSN+ P F + +L+ F
Sbjct 206 LSNLSVLALQNNRLSGALSSKLGKLSN--LGRLDISSNKFSGKIPDVFLELNKLW-YFSA 262
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLK-WTNLTMLDLSYN 284
L ++ L+N+ R++SL + + +T S +L TNLT LDL+ N
Sbjct 263 QSNL---FNGEMPRSLSNS--RSISLLSLRNNTLSGQIYLNCSAMTNLTSLDLASN 313
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 142/569 (25%), Positives = 218/569 (38%), Gaps = 162/569 (28%)
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSI 135
++ L++G +S E KL LKVLNL HN LS + +NL L L SN
Sbjct 64 RVVELELGRRKLSGKLSESVAKLDQLKVLNLTHNSLSGSIAASLLNLSNLEVLDLSSNDF 123
Query 136 QKIKNNPFVKQKNLITLDL------SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSE 189
+ F NL +L + S +GL L L ++E+ L+ N S
Sbjct 124 SGL----FPSLINLPSLRVLNVYENSFHGLIPASLCN--NLPRIREIDLAMNYFDG--SI 175
Query 190 ELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS 249
+ I SS++ L L+SN + P + L L L N +L +L+ KL
Sbjct 176 PVGIGNCSSVEYLGLASNNLSGSIPQELFQLSNLSVLALQNNRLSGALSSKLG------- 228
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
K +NL LD+S N + D F L +L YF + N
Sbjct 229 ----------------------KLSNLGRLDISSNKFSGKIPDVFLELNKLWYFSAQSN- 265
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFT-KQSISLASLPKIDDFSFQ-WLKCLEHLNMEDNDI 367
LFN + RS + +SISL SL + + S Q +L C N+ D
Sbjct 266 -----------LFNGE---MPRSLSNSRSISLLSL-RNNTLSGQIYLNCSAMTNLTSLD- 309
Query 368 PGIKSNMFTGLI----------------NLKYLS-LSNSFTSLRTLTNETFVS------- 403
+ SN F+G I +K+++ + SF + ++LT+ +F +
Sbjct 310 --LASNSFSGSIPSNLPNCLRLKTINFAKIKFIAQIPESFKNFQSLTSLSFSNSSIQNIS 367
Query 404 -----LAH-----SPLHILNLTKNKISKIESDAF------------------SWLGH--- 432
L H + + LN K ++ + S F WL +
Sbjct 368 SALEILQHCQNLKTLVLTLNFQKEELPSVPSLQFKNLKVLIIASCQLRGTVPQWLSNSPS 427
Query 433 LEVLDLGLNEIGQELTGQEWRG-LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVA 491
L++LDL N++ + W G L ++F + LS N ++ +S SLQ L+ +
Sbjct 428 LQLLDLSWNQLSGTIP--PWLGSLNSLFYLDLSNNTFIGEIPHSLT---SLQSLVSKXXX 482
Query 492 LKNVD------------------SSPSPFQP-------------------LRNLTILDLS 514
+ PS F P LR L +L+L
Sbjct 483 XXXXXPDFPFFKKXXXXXGGLQYNQPSSFPPMIDLSYNSLNGSIWPEFGDLRQLHVLNLK 542
Query 515 NNNIANINDDMLEGLEKLEILDLQHNNLA 543
NNN++ L G+ LE+LDL HNNL+
Sbjct 543 NNNLSGNIPANLSGMTSLEVLDLSHNNLS 571
>3oja_B B Anopheles Plasmodium-responsive Leucine-rich repeat
protein 1
Length=597
Score = 60.1 bits (144), Expect = 8e-08, Method: Compositional matrix adjust.
Identities = 67/258 (26%), Positives = 112/258 (43%), Gaps = 44/258 (17%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
+ +LNL Q+ + F + L +GFN I L P + Q +P+L VL L+ N+LS
Sbjct 77 VELLNLNDLQIEEIDTYAFAYAHTIQKLYMGFNAIRYLPPHVFQNVPLLTVLVLERNDLS 136
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
L F LT L + +N++++I+++ F +L L LS N L T V L
Sbjct 137 SLPRGIFHNTPKLTTLSMSNNNLERIEDDTFQATTSLQNLQLSSNRL------THVDLSL 190
Query 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ 232
+ L +N L + + I ++++L+ S N I NV
Sbjct 191 IPSLFHANVSYNLLSTLAIPI----AVEELDASHNSI--------------------NVV 226
Query 233 LGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGND 292
GP E L+L + ++ ++T +L L + L +DLSYN L +
Sbjct 227 RGPVNVELTILKLQHNNL-------------TDTAWL-LNYPGLVEVDLSYNELEKIMYH 272
Query 293 SFAWLPQLEYFFLEYNNI 310
F + +LE ++ N +
Sbjct 273 PFVKMQRLERLYISNNRL 290
Score = 44.3 bits (103), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 71/319 (22%), Positives = 142/319 (45%), Gaps = 51/319 (16%)
Query 252 NLSLSNSQLSTTSNTTFLGL------KWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFL 305
+++L+N ++ T N+T L + + +L+L+ + + +FA+ ++ ++
Sbjct 47 DITLNNQKIVTFKNSTMRKLPAALLDSFRQVELLNLNDLQIEEIDTYAFAYAHTIQKLYM 106
Query 306 EYNNIQHLFSHSLHGLFNVRYLNLKRS---------------FTKQSISLASLPKIDDFS 350
+N I++L H + + L L+R+ T S+S +L +I+D +
Sbjct 107 GFNAIRYLPPHVFQNVPLLTVLVLERNDLSSLPRGIFHNTPKLTTLSMSNNNLERIEDDT 166
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLH 410
FQ L++L + N + + ++ L + S+ L TL V + +
Sbjct 167 FQATTSLQNLQLSSNRLTHVDLSLIPSLFHANV-----SYNLLSTLAIPIAVEELDASHN 221
Query 411 ILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWR-GLENIFEIYLSYNKYL 469
+N+ + ++ L +L L N LT W + E+ LSYN+
Sbjct 222 SINVVRGPVN----------VELTILKLQHNN----LTDTAWLLNYPGLVEVDLSYNELE 267
Query 470 QLTRNSFALVPSLQRLML---RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
++ + F + L+RL + R VAL N+ P P L +LDLS+N++ ++ +
Sbjct 268 KIMYHPFVKMQRLERLYISNNRLVAL-NLYGQPIP-----TLKVLDLSHNHLLHVERNQP 321
Query 527 EGLEKLEILDLQHNNLARL 545
+ ++LE L L HN++ L
Sbjct 322 Q-FDRLENLYLDHNSIVTL 339
Score = 38.9 bits (89), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 67/256 (26%), Positives = 105/256 (41%), Gaps = 39/256 (15%)
Query 395 TLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRG 454
TL N+ V+ +S T K+ D+F + L + DL + EI +
Sbjct 49 TLNNQKIVTFKNS-------TMRKLPAALLDSFRQVELLNLNDLQIEEID----TYAFAY 97
Query 455 LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP-FQPLRNLTILDL 513
I ++Y+ +N L + F VP L L+L R ++ S P F LT L +
Sbjct 98 AHTIQKLYMGFNAIRYLPPHVFQNVPLLTVLVLER---NDLSSLPRGIFHNTPKLTTLSM 154
Query 514 SNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI-LNLESN 572
SNNN+ I DD + L+ L L N L + + + L H ++ NL S
Sbjct 155 SNNNLERIEDDTFQATTSLQNLQLSSNRLTHV--------DLSLIPSLFHANVSYNLLST 206
Query 573 GFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP 632
IP+ V + +D N++N + V V L L LQ N +T + P
Sbjct 207 L--AIPIAVEE-------LDASHNSINVVRGPV---NVELTILKLQHNNLTDTAWLLNYP 254
Query 633 AFRNLTELDMRFNPFD 648
L E+D+ +N +
Sbjct 255 G---LVEVDLSYNELE 267
Score = 35.8 bits (81), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 67/255 (26%), Positives = 115/255 (45%), Gaps = 35/255 (14%)
Query 343 LPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSL-RTLTNET 400
+ +ID ++F + ++ L M N I + ++F + L L L N +SL R + + T
Sbjct 87 IEEIDTYAFAYAHTIQKLYMGFNAIRYLPPHVFQNVPLLTVLVLERNDLSSLPRGIFHNT 146
Query 401 FVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFE 460
L L+++ N + +IE D F L+ L L N LT + + ++F
Sbjct 147 ------PKLTTLSMSNNNLERIEDDTFQATTSLQNLQLSSNR----LTHVDLSLIPSLFH 196
Query 461 IYLSYN-----------KYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRN-- 507
+SYN + L + NS +V + L + L++ + + + + L N
Sbjct 197 ANVSYNLLSTLAIPIAVEELDASHNSINVVRGPVNVELTILKLQHNNLTDTAW--LLNYP 254
Query 508 -LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLK--GLSHL 564
L +DLS N + I +++LE L + +N L L + G PI LK LSH
Sbjct 255 GLVEVDLSYNELEKIMYHPFVKMQRLERLYISNNRLVALNLY---GQPIPTLKVLDLSHN 311
Query 565 HILNLESN--GFDEI 577
H+L++E N FD +
Sbjct 312 HLLHVERNQPQFDRL 326
Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 50/184 (27%), Positives = 74/184 (40%), Gaps = 33/184 (18%)
Query 24 STTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVG 83
ST ++ E D SH + V + +T+L L HN L A Y L +D+
Sbjct 205 STLAIPIAVEELDASHNSINVVRGPVNVELTILKLQHNNL--TDTAWLLNYPGLVEVDLS 262
Query 84 FNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
+N + K+ K+ L+ L + +N L L+L I +K
Sbjct 263 YNELEKIMYHPFVKMQRLERLYISNNR--------------LVALNLYGQPIPTLK---- 304
Query 144 VKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
LDLSHN L + Q Q + L+ L L +N I LK + + +LK L
Sbjct 305 -------VLDLSHNHLLHVE-RNQPQFDRLENLYLDHNSIVTLK-----LSTHHTLKNLT 351
Query 204 LSSN 207
LS N
Sbjct 352 LSHN 355
>6bxc_D C Variable Lymphocyte Receptor 9 (VLR9)
Length=178
Score = 56.6 bits (135), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 51/99 (52%), Gaps = 1/99 (1%)
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+L L N ++ VF L L+ + L +N L +LPA VF+N L LN+ N + S
Sbjct 49 QVLYLYDNQITKLEPGVFDRLVNLQQLWLEINQLTSLPAGVFDNLTQLSILNMHTNQLKS 108
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ + F ++LT + + NP+DC C I + W+ +
Sbjct 109 IPRGAFD-NLKSLTHIWLLNNPWDCACSDILYLSGWLGQ 146
Score = 54.3 bits (129), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 0/112 (0%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLD 81
+ ++C+ S DCS L VP +PT VL L NQ+ +L F R L L
Sbjct 17 GACPSQCSCSGTTVDCSGKSLASVPGGIPTTTQVLYLYDNQITKLEPGVFDRLVNLQQLW 76
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ N ++ L + L L +LN+ N+L + F +LT + L++N
Sbjct 77 LEINQLTSLPAGVFDNLTQLSILNMHTNQLKSIPRGAFDNLKSLTHIWLLNN 128
>4z5w_B B Phytosulfokine receptor 1
Length=642
Score = 60.1 bits (144), Expect = 9e-08, Method: Compositional matrix adjust.
Identities = 76/241 (32%), Positives = 108/241 (45%), Gaps = 25/241 (10%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
+ VLNLTHN L AA+ S L LD+ N S L P L LP L+VLN+ N
Sbjct 89 LKVLNLTHNSLSGSIAASLLNLSNLEVLDLSSNDFSGLFPSLI-NLPSLRVLNVYENSFH 147
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT---LDLSHNGLSSTKLGTQVQ 169
L + C NL + + ++ + V N + L L+ N LS + Q
Sbjct 148 GLIPAS--LCNNLPRIREIDLAMNYFDGSIPVGIGNCSSVEYLGLASNNLSGSIPQELFQ 205
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLF----- 224
L NL L L NN++ S +L +N L +L++SSN+ P F + +L+
Sbjct 206 LSNLSVLALQNNRLSGALSSKLGKLSN--LGRLDISSNKFSGKIPDVFLELNKLWYFSAQ 263
Query 225 -GLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
LF N ++ SL+ + L S+RN +LS S TNLT LDL+
Sbjct 264 SNLF--NGEMPRSLSNSRSISL--LSLRNNTLSGQIYLNCS-------AMTNLTSLDLAS 312
Query 284 N 284
N
Sbjct 313 N 313
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 142/569 (25%), Positives = 218/569 (38%), Gaps = 162/569 (28%)
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSI 135
++ L++G +S E KL LKVLNL HN LS + +NL L L SN
Sbjct 64 RVVELELGRRKLSGKLSESVAKLDQLKVLNLTHNSLSGSIAASLLNLSNLEVLDLSSNDF 123
Query 136 QKIKNNPFVKQKNLITLDL------SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSE 189
+ F NL +L + S +GL L L ++E+ L+ N S
Sbjct 124 SGL----FPSLINLPSLRVLNVYENSFHGLIPASLCN--NLPRIREIDLAMNYFDG--SI 175
Query 190 ELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS 249
+ I SS++ L L+SN + P + L L L N +L +L+ KL
Sbjct 176 PVGIGNCSSVEYLGLASNNLSGSIPQELFQLSNLSVLALQNNRLSGALSSKLG------- 228
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
K +NL LD+S N + D F L +L YF + N
Sbjct 229 ----------------------KLSNLGRLDISSNKFSGKIPDVFLELNKLWYFSAQSN- 265
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFT-KQSISLASLPKIDDFSFQ-WLKCLEHLNMEDNDI 367
LFN + RS + +SISL SL + + S Q +L C N+ D
Sbjct 266 -----------LFNGE---MPRSLSNSRSISLLSL-RNNTLSGQIYLNCSAMTNLTSLD- 309
Query 368 PGIKSNMFTGLI----------------NLKYLS-LSNSFTSLRTLTNETFVS------- 403
+ SN F+G I +K+++ + SF + ++LT+ +F +
Sbjct 310 --LASNSFSGSIPSNLPNCLRLKTINFAKIKFIAQIPESFKNFQSLTSLSFSNSSIQNIS 367
Query 404 -----LAH-----SPLHILNLTKNKISKIESDAF------------------SWLGH--- 432
L H + + LN K ++ + S F WL +
Sbjct 368 SALEILQHCQNLKTLVLTLNFQKEELPSVPSLQFKNLKVLIIASCQLRGTVPQWLSNSPS 427
Query 433 LEVLDLGLNEIGQELTGQEWRG-LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVA 491
L++LDL N++ + W G L ++F + LS N ++ +S SLQ L+ +
Sbjct 428 LQLLDLSWNQLSGTIP--PWLGSLNSLFYLDLSNNTFIGEIPHSLT---SLQSLVSKXXX 482
Query 492 LKNVD------------------SSPSPFQP-------------------LRNLTILDLS 514
+ PS F P LR L +L+L
Sbjct 483 XXXXXXDFPFFKKXXXXXXXLQYNQPSSFPPMIDLSYNSLNGSIWPEFGDLRQLHVLNLK 542
Query 515 NNNIANINDDMLEGLEKLEILDLQHNNLA 543
NNN++ L G+ LE+LDL HNNL+
Sbjct 543 NNNLSGNIPANLSGMTSLEVLDLSHNNLS 571
>6bxe_B B Variable lymphocyte receptor diversity region
Length=178
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 51/99 (52%), Gaps = 1/99 (1%)
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+L L N ++ VF L L+ + L +N L +LPA VF+N L LN+ N + S
Sbjct 49 QVLYLYDNQITKLEPGVFDRLVNLQQLWLEINQLTSLPAGVFDNLTQLSILNMHTNQLKS 108
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ + F ++LT + + NP+DC C I + W+ +
Sbjct 109 IPRGAFD-NLKSLTHIWLLNNPWDCACSDILYLSGWLGQ 146
Score = 53.9 bits (128), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 0/112 (0%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLD 81
+ ++C+ S DCS L VP +PT VL L NQ+ +L F R L L
Sbjct 17 GACPSQCSCSGTTVDCSGKSLASVPGGIPTTTQVLYLYDNQITKLEPGVFDRLVNLQQLW 76
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ N ++ L + L L +LN+ N+L + F +LT + L++N
Sbjct 77 LEINQLTSLPAGVFDNLTQLSILNMHTNQLKSIPRGAFDNLKSLTHIWLLNN 128
>6bxc_C D Variable Lymphocyte Receptor 9 (VLR9)
Length=178
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 51/99 (52%), Gaps = 1/99 (1%)
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+L L N ++ VF L L+ + L +N L +LPA VF+N L LN+ N + S
Sbjct 49 QVLYLYDNQITKLEPGVFDRLVNLQQLWLEINQLTSLPAGVFDNLTQLSILNMHTNQLKS 108
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ + F ++LT + + NP+DC C I + W+ +
Sbjct 109 IPRGAFD-NLKSLTHIWLLNNPWDCACSDILYLSGWLGQ 146
Score = 53.9 bits (128), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 0/112 (0%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLD 81
+ ++C+ S DCS L VP +PT VL L NQ+ +L F R L L
Sbjct 17 GACPSQCSCSGTTVDCSGKSLASVPGGIPTTTQVLYLYDNQITKLEPGVFDRLVNLQQLW 76
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ N ++ L + L L +LN+ N+L + F +LT + L++N
Sbjct 77 LEINQLTSLPAGVFDNLTQLSILNMHTNQLKSIPRGAFDNLKSLTHIWLLNN 128
>4z62_A A Phytosulfokine receptor 1
Length=642
Score = 59.7 bits (143), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 76/241 (32%), Positives = 108/241 (45%), Gaps = 25/241 (10%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
+ VLNLTHN L AA+ S L LD+ N S L P L LP L+VLN+ N
Sbjct 89 LKVLNLTHNSLSGSIAASLLNLSNLEVLDLSSNDFSGLFPSLI-NLPSLRVLNVYENSFH 147
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT---LDLSHNGLSSTKLGTQVQ 169
L + C NL + + ++ + V N + L L+ N LS + Q
Sbjct 148 GLIPAS--LCNNLPRIREIDLAMNYFDGSIPVGIGNCSSVEYLGLASNNLSGSIPQELFQ 205
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLF----- 224
L NL L L NN++ S +L +N L +L++SSN+ P F + +L+
Sbjct 206 LSNLSVLALQNNRLSGALSSKLGKLSN--LGRLDISSNKFSGKIPDVFLELNKLWYFSAQ 263
Query 225 -GLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSY 283
LF N ++ SL+ + L S+RN +LS S TNLT LDL+
Sbjct 264 SNLF--NGEMPRSLSNSRSISL--LSLRNNTLSGQIYLNCS-------AMTNLTSLDLAS 312
Query 284 N 284
N
Sbjct 313 N 313
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 144/566 (25%), Positives = 224/566 (40%), Gaps = 156/566 (28%)
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSI 135
++ L++G +S E KL LKVLNL HN LS + +NL L L SN
Sbjct 64 RVVELELGRRKLSGKLSESVAKLDQLKVLNLTHNSLSGSIAASLLNLSNLEVLDLSSNDF 123
Query 136 QKIKNNPFVKQKNLITLDL------SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSE 189
+ F NL +L + S +GL L L ++E+ L+ N S
Sbjct 124 SGL----FPSLINLPSLRVLNVYENSFHGLIPASLCNN--LPRIREIDLAMNYFDG--SI 175
Query 190 ELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS 249
+ I SS++ L L+SN + P + L L L N +L +L+ KL
Sbjct 176 PVGIGNCSSVEYLGLASNNLSGSIPQELFQLSNLSVLALQNNRLSGALSSKLG------- 228
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
K +NL LD+S N + D F L +L YF + N
Sbjct 229 ----------------------KLSNLGRLDISSNKFSGKIPDVFLELNKLWYFSAQSN- 265
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFT-KQSISLASLPKIDDFSFQ-WLKC-----LEHLNM 362
LFN + RS + +SISL SL + + S Q +L C L L++
Sbjct 266 -----------LFNGE---MPRSLSNSRSISLLSL-RNNTLSGQIYLNCSAMTNLTSLDL 310
Query 363 EDNDIPG-IKSNMFTGL----IN---LKYLS-LSNSFTSLRTLTNETFVS---------- 403
N G I SN+ L IN +K+++ + SF + ++LT+ +F +
Sbjct 311 ASNSFSGSIPSNLPNCLRLKTINFAKIKFIAQIPESFKNFQSLTSLSFSNSSIQNISSAL 370
Query 404 --LAH-----SPLHILNLTKNKISKIESDAFS------------------WLGH---LEV 435
L H + + LN K ++ + S F WL + L++
Sbjct 371 EILQHCQNLKTLVLTLNFQKEELPSVPSLQFKNLKVLIIASCQLRGTVPQWLSNSPSLQL 430
Query 436 LDLGLNEIGQELTGQEWRG-LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRR----- 489
LDL N++ + W G L ++F + LS N ++ +S SLQ L+ +
Sbjct 431 LDLSWNQLSGTIP--PWLGSLNSLFYLDLSNNTFIGEIPHSLT---SLQSLVSKXXXXXX 485
Query 490 -------------------------------VALKNVDSSPSP-FQPLRNLTILDLSNNN 517
++ +++ S P F LR L +L+L NNN
Sbjct 486 XXXXXXXXXXXXXXXXXXXXXXXXXFPPMIDLSYNSLNGSIWPEFGDLRQLHVLNLKNNN 545
Query 518 IANINDDMLEGLEKLEILDLQHNNLA 543
++ L G+ LE+LDL HNNL+
Sbjct 546 LSGNIPANLSGMTSLEVLDLSHNNLS 571
Score = 37.7 bits (86), Expect = 0.71, Method: Compositional matrix adjust.
Identities = 41/144 (28%), Positives = 72/144 (50%), Gaps = 15/144 (10%)
Query 505 LRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHL 564
L L +L+L++N+++ L L LE+LDL N+ + L+ L L L
Sbjct 86 LDQLKVLNLTHNSLSGSIAASLLNLSNLEVLDLSSNDFSGLFPS---------LINLPSL 136
Query 565 HILNLESNGFDE-IPVEVFKDLFELKIIDLGLNNLN-TLPASVFNNQVSLKSLNLQK-NL 621
+LN+ N F IP + +L ++ IDL +N + ++P + N S++ L L NL
Sbjct 137 RVLNVYENSFHGLIPASLCNNLPRIREIDLAMNYFDGSIPVGI-GNCSSVEYLGLASNNL 195
Query 622 ITSVEKKVFGPAFRNLTELDMRFN 645
S+ +++F NL+ L ++ N
Sbjct 196 SGSIPQELF--QLSNLSVLALQNN 217
>6bxe_A A Variable lymphocyte receptor diversity region
Length=178
Score = 56.2 bits (134), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 31/99 (31%), Positives = 51/99 (52%), Gaps = 1/99 (1%)
Query 565 HILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+L L N ++ VF L L+ + L +N L +LPA VF+N L LN+ N + S
Sbjct 49 QVLYLYDNQITKLEPGVFDRLVNLQQLWLEINQLTSLPAGVFDNLTQLSILNMHTNQLKS 108
Query 625 VEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
+ + F ++LT + + NP+DC C I + W+ +
Sbjct 109 IPRGAFD-NLKSLTHIWLLNNPWDCACSDILYLSGWLGQ 146
Score = 53.1 bits (126), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 33/108 (31%), Positives = 51/108 (47%), Gaps = 0/108 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S DCS L VP +PT VL L NQ+ +L F R L L + N
Sbjct 21 SQCSCSGTTVDCSGKSLASVPGGIPTTTQVLYLYDNQITKLEPGVFDRLVNLQQLWLEIN 80
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
++ L + L L +LN+ N+L + F +LT + L++N
Sbjct 81 QLTSLPAGVFDNLTQLSILNMHTNQLKSIPRGAFDNLKSLTHIWLLNN 128
>4rcw_B B SLIT and NTRK-like protein 1
Length=240
Score = 57.4 bits (137), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 52/166 (31%), Positives = 85/166 (51%), Gaps = 10/166 (6%)
Query 95 CQKLPMLKV-LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
C +P + +N + +S L+D +N+ EL L N I I+ + FV KNLI LD
Sbjct 7 CDHIPGSGLKMNCNNRNVSSLADXXXXX-SNVQELFLRDNKIHSIRKSHFVDYKNLILLD 65
Query 154 LSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
L +N +++ + T L +L+ L + +N + L E+ N L+ L + N I+
Sbjct 66 LGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQN--LEYLNVEYNAIQLIL 123
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLEL-ANTSIRNLSLSNS 258
PG F+A+ +L L LNN +L L +++ A S+ LSL N+
Sbjct 124 PGTFNAMPKLRILILNN-----NLLRSLPVDVFAGVSLSKLSLHNN 164
Score = 46.2 bits (108), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 51/214 (24%), Positives = 86/214 (40%), Gaps = 34/214 (16%)
Query 493 KNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPG 552
+NV S N+ L L +N I +I + L +LDL +NN+A + +
Sbjct 22 RNVSSLADXXXXXSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNT--- 78
Query 553 GPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
K L L L ++SN D + E F L L+ +++ N + + FN L
Sbjct 79 -----FKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKL 133
Query 613 KSLNLQKNLITSVEKKVFGPA-----------------------FRNLTELDMRFNPFDC 649
+ L L NL+ S+ VF ++ ++D+ NP++C
Sbjct 134 RILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWEC 193
Query 650 TCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
+C +I F W + + L S C TP ++
Sbjct 194 SC-TIVPFKQWAERLGSEV--LMSDLKCETPVNF 224
Score = 41.6 bits (96), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 39/143 (27%), Positives = 76/143 (53%), Gaps = 12/143 (8%)
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEY 307
++++ L L ++++ + + F+ K NL +LDL NN+ V N++F L L + +++
Sbjct 35 SNVQELFLRDNKIHSIRKSHFVDYK--NLILLDLGNNNIATVENNTFKNLLDLRWLYMDS 92
Query 308 NNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDI 367
N + L GL N+ YLN++ + +I L LP +F + L L + +N +
Sbjct 93 NYLDTLSREKFAGLQNLEYLNVEYN----AIQLI-LPG----TFNAMPKLRILILNNNLL 143
Query 368 PGIKSNMFTGLINLKYLSLSNSF 390
+ ++F G ++L LSL N++
Sbjct 144 RSLPVDVFAG-VSLSKLSLHNNY 165
Score = 36.6 bits (83), Expect = 0.94, Method: Compositional matrix adjust.
Identities = 39/130 (30%), Positives = 63/130 (48%), Gaps = 9/130 (7%)
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
L NKI I F +L +LDLG N I + ++ L ++ +Y+ N L+R
Sbjct 42 LRDNKIHSIRKSHFVDYKNLILLDLGNNNIAT-VENNTFKNLLDLRWLYMDSNYLDTLSR 100
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG--LEK 531
FA + +L+ L + A++ + P F + L IL L+NN + ++ D+ G L K
Sbjct 101 EKFAGLQNLEYLNVEYNAIQLI--LPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSK 158
Query 532 LEILDLQHNN 541
L + HNN
Sbjct 159 LSL----HNN 164
>4rcw_A A SLIT and NTRK-like protein 1
Length=240
Score = 57.4 bits (137), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 52/166 (31%), Positives = 85/166 (51%), Gaps = 10/166 (6%)
Query 95 CQKLPMLKV-LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
C +P + +N + +S L+D +N+ EL L N I I+ + FV KNLI LD
Sbjct 7 CDHIPGXGLKMNCNNRNVSSLADLKXXX-SNVQELFLRDNKIHSIRKSHFVDYKNLILLD 65
Query 154 LSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
L +N +++ + T L +L+ L + +N + L E+ N L+ L + N I+
Sbjct 66 LGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQN--LEYLNVEYNAIQLIL 123
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLEL-ANTSIRNLSLSNS 258
PG F+A+ +L L LNN +L L +++ A S+ LSL N+
Sbjct 124 PGTFNAMPKLRILILNN-----NLLRSLPVDVFAGVSLSKLSLHNN 164
Score = 44.7 bits (104), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 51/214 (24%), Positives = 86/214 (40%), Gaps = 34/214 (16%)
Query 493 KNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPG 552
+NV S N+ L L +N I +I + L +LDL +NN+A + +
Sbjct 22 RNVSSLADLKXXXSNVQELFLRDNKIHSIRKSHFVDYKNLILLDLGNNNIATVENNT--- 78
Query 553 GPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSL 612
K L L L ++SN D + E F L L+ +++ N + + FN L
Sbjct 79 -----FKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVEYNAIQLILPGTFNAMPKL 133
Query 613 KSLNLQKNLITSVEKKVFGPA-----------------------FRNLTELDMRFNPFDC 649
+ L L NL+ S+ VF ++ ++D+ NP++C
Sbjct 134 RILILNNNLLRSLPVDVFAGVSLSKLSLHNNYFMYLPVAGVLDQLTSIIQIDLHGNPWEC 193
Query 650 TCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
+C +I F W + + L S C TP ++
Sbjct 194 SC-TIVPFKQWAERLGSEV--LMSDLKCETPVNF 224
Score = 43.1 bits (100), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 49/180 (27%), Positives = 90/180 (50%), Gaps = 19/180 (11%)
Query 214 PG---CFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLG 270
PG C H G + NN + SL + L+ ++++ L L ++++ + + F+
Sbjct 2 PGGCSCDHIPGXGLKMNCNNRNVS-SLAD---LKXXXSNVQELFLRDNKIHSIRKSHFVD 57
Query 271 LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
K NL +LDL NN+ V N++F L L + +++ N + L GL N+ YLN++
Sbjct 58 YK--NLILLDLGNNNIATVENNTFKNLLDLRWLYMDSNYLDTLSREKFAGLQNLEYLNVE 115
Query 331 RSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSF 390
+ +I L LP +F + L L + +N + + ++F G ++L LSL N++
Sbjct 116 YN----AIQLI-LPG----TFNAMPKLRILILNNNLLRSLPVDVFAG-VSLSKLSLHNNY 165
Score = 36.2 bits (82), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 39/130 (30%), Positives = 63/130 (48%), Gaps = 9/130 (7%)
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
L NKI I F +L +LDLG N I + ++ L ++ +Y+ N L+R
Sbjct 42 LRDNKIHSIRKSHFVDYKNLILLDLGNNNIAT-VENNTFKNLLDLRWLYMDSNYLDTLSR 100
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG--LEK 531
FA + +L+ L + A++ + P F + L IL L+NN + ++ D+ G L K
Sbjct 101 EKFAGLQNLEYLNVEYNAIQLI--LPGTFNAMPKLRILILNNNLLRSLPVDVFAGVSLSK 158
Query 532 LEILDLQHNN 541
L + HNN
Sbjct 159 LSL----HNN 164
>5d3i_A A Toll-like receptor 2
Length=568
Score = 59.3 bits (142), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 138/582 (24%), Positives = 237/582 (41%), Gaps = 112/582 (19%)
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+LDLS N ++ G NLQ L+L +++I ++ + ++ SL+ L+LS N +
Sbjct 34 SLDLSFNKITYIGHGDLRACANLQVLILKSSRINTIEGDAF--YSLGSLEHLDLSDNHLS 91
Query 211 EFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNLSLSNSQ-LSTTSNTTF 268
S F G L L N+ P T + N T+++ L + N + S F
Sbjct 92 SLSSSWF---GPLSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDF 148
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
GL T+L L++ +L + S + + + L + L L +VRYL
Sbjct 149 AGL--TSLNELEIKALSLRNYQSQSLKSIRDIHHLTLHLSESAFLLEIFADILSSVRYLE 206
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
L R + LP +D+ S +K F G +
Sbjct 207 L-RDTNLARFQFSPLP-VDEVS-----------------SPMKKLAFRGSV--------- 238
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI-----------ESDAFSWLGHLEVLD 437
LT+E+F L +IL L++ + ESD S LG +E +
Sbjct 239 -------LTDESFNELLKLLRYILELSEVEFDDCTLNGLGDFNPSESDVVSELGKVETVT 291
Query 438 L------------GLNEIGQELTGQEWRGLEN--IFEIYLSYNKYL-------------- 469
+ L+ + L + +EN +F + S++++L
Sbjct 292 IRRLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMV 351
Query 470 -QLTRNSF--ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
+ +NS PSLQ L+L + L+++ + L+NLT LD+S N + D
Sbjct 352 EEYLKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPMPDSC- 410
Query 527 EGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLF 586
+ EK+ L+L + R+ K P L +L++ +N D + L
Sbjct 411 QWPEKMRFLNLSSTGI-RVVKTCIP----------QTLEVLDVSNNNLDSFSL-FLPRLQ 458
Query 587 ELKIIDLGLNNLNTLP-ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
EL I N L TLP AS+F + +K +++N +++ K G +F L L+ N
Sbjct 459 ELYI---SRNKLKTLPDASLFPVLLVMK---IRENAVSTFSKDQLG-SFPKLETLEAGDN 511
Query 646 PFDCTCESIAWFVN--WINETHTNIPELSSHYLCNTPPHYHG 685
F C+CE +++ + + + + P+ YLC++PP HG
Sbjct 512 HFVCSCELLSFTMETPALAQILVDWPD---SYLCDSPPRLHG 550
Score = 37.4 bits (85), Expect = 0.78, Method: Compositional matrix adjust.
Identities = 112/498 (22%), Positives = 207/498 (42%), Gaps = 74/498 (15%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K L+L N+++ + C NL L L S+ I I+ + F +L LDLS N LS
Sbjct 32 MKSLDLSFNKITYIGHGDLRACANLQVLILKSSRINTIEGDAFYSLGSLEHLDLSDNHLS 91
Query 161 STK---------------LGTQVQ----------LENLQELLLSNNKIQALKSEELDIFA 195
S +G Q L NLQ L + N + + + +D
Sbjct 92 SLSSSWFGPLSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFS-EIRRIDFAG 150
Query 196 NSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEK-LCLELAN---TSIR 251
+SL +LE+ + ++ + +I + L L+ L+E LE+ +S+R
Sbjct 151 LTSLNELEIKALSLRNYQSQSLKSIRDIHHLTLH-------LSESAFLLEIFADILSSVR 203
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
L L ++ L+ + L + + M L++ +V+ ++SF L +L + LE + ++
Sbjct 204 YLELRDTNLARFQFSP-LPVDEVSSPMKKLAFRG-SVLTDESFNELLKLLRYILELSEVE 261
Query 312 HLFSHSLHGL--FN------VRYLNLKRSFTKQSISLASLPKIDDFS--FQWLKCLEHLN 361
+L+GL FN V L + T + + + D S + L+ ++ +
Sbjct 262 -FDDCTLNGLGDFNPSESDVVSELGKVETVTIRRLHIPQFYLFYDLSTVYSLLEKVKRIT 320
Query 362 MEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISK 421
+E++ + + + L +L++L LS + L N A L L L++N +
Sbjct 321 VENSKVFLVPCSFSQHLKSLEFLDLSENLMVEEYLKNSACKG-AWPSLQTLVLSQNHLRS 379
Query 422 IE--SDAFSWLGHLEVLDLGLNEIGQELTGQEW-----------RGLENIFEIYLSYNKY 468
++ + L +L LD+ N +W G+ + +
Sbjct 380 MQKTGEILLTLKNLTSLDISRNTFHPMPDSCQWPEKMRFLNLSSTGIRVVKTCIPQTLEV 439
Query 469 LQLTRN---SFAL-VPSLQRLMLRRVALKNV-DSSPSPFQPLRNLTILDLSNNNIANIND 523
L ++ N SF+L +P LQ L + R LK + D+S P L ++ + N ++ +
Sbjct 440 LDVSNNNLDSFSLFLPRLQELYISRNKLKTLPDASLFPV-----LLVMKIRENAVSTFSK 494
Query 524 DMLEGLEKLEILDLQHNN 541
D L KLE L+ N+
Sbjct 495 DQLGSFPKLETLEAGDNH 512
>8hpw_B B Leucine-rich glioma-inactivated protein 1
Length=202
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIFK-GLDSLTNVDLRGNAFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Score = 47.8 bits (112), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 36/116 (31%), Positives = 64/116 (55%), Gaps = 11/116 (9%)
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
+ +LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NN
Sbjct 38 VISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
I+ + H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 41.6 bits (96), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 34/119 (29%), Positives = 54/119 (45%), Gaps = 10/119 (8%)
Query 457 NIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
++ + + + +++ SF PSLQ L+ + + S F L +L L + NN
Sbjct 37 DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENN 94
Query 517 NIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
NI +I+ GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 95 NIKSISRHTFRGLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNAFN 145
Score = 37.0 bits (84), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLRRVAL 492
L ++ F + SL + LR A
Sbjct 121 QTLPKDIFKGLDSLTNVDLRGNAF 144
Score = 36.2 bits (82), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 34.7 bits (78), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 24/59 (41%), Positives = 37/59 (63%), Gaps = 2/59 (3%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F L
Sbjct 75 ISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIFKGL 131
Score = 33.5 bits (75), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 67/144 (47%), Gaps = 13/144 (9%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGL-KSLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNAF 144
Query 444 GQELTGQ---EWRGLEN--IFEIY 462
+ + EW G N + +IY
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIY 168
>8hpx_B B Leucine-rich glioma-inactivated protein 1
Length=202
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIFK-GLDSLTNVDLRGNAFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Score = 47.8 bits (112), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 36/116 (31%), Positives = 64/116 (55%), Gaps = 11/116 (9%)
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
+ +LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NN
Sbjct 38 VISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
I+ + H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 41.6 bits (96), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 34/119 (29%), Positives = 54/119 (45%), Gaps = 10/119 (8%)
Query 457 NIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
++ + + + +++ SF PSLQ L+ + + S F L +L L + NN
Sbjct 37 DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENN 94
Query 517 NIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
NI +I+ GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 95 NIKSISRHTFRGLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNAFN 145
Score = 37.0 bits (84), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLRRVAL 492
L ++ F + SL + LR A
Sbjct 121 QTLPKDIFKGLDSLTNVDLRGNAF 144
Score = 36.2 bits (82), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 34.7 bits (78), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 24/59 (41%), Positives = 37/59 (63%), Gaps = 2/59 (3%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F L
Sbjct 75 ISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIFKGL 131
Score = 33.5 bits (75), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 67/144 (47%), Gaps = 13/144 (9%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGL-KSLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNAF 144
Query 444 GQELTGQ---EWRGLEN--IFEIY 462
+ + EW G N + +IY
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIY 168
>8hpx_A A Leucine-rich glioma-inactivated protein 1
Length=202
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIFK-GLDSLTNVDLRGNAFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Score = 47.8 bits (112), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 36/116 (31%), Positives = 64/116 (55%), Gaps = 11/116 (9%)
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
+ +LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NN
Sbjct 38 VISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
I+ + H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 41.6 bits (96), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 34/119 (29%), Positives = 54/119 (45%), Gaps = 10/119 (8%)
Query 457 NIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
++ + + + +++ SF PSLQ L+ + + S F L +L L + NN
Sbjct 37 DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENN 94
Query 517 NIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
NI +I+ GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 95 NIKSISRHTFRGLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNAFN 145
Score = 37.0 bits (84), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLRRVAL 492
L ++ F + SL + LR A
Sbjct 121 QTLPKDIFKGLDSLTNVDLRGNAF 144
Score = 36.2 bits (82), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 34.7 bits (78), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 24/59 (41%), Positives = 37/59 (63%), Gaps = 2/59 (3%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F L
Sbjct 75 ISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIFKGL 131
Score = 33.5 bits (75), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 67/144 (47%), Gaps = 13/144 (9%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGL-KSLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNAF 144
Query 444 GQELTGQ---EWRGLEN--IFEIY 462
+ + EW G N + +IY
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIY 168
>8hpw_C C Leucine-rich glioma-inactivated protein 1
Length=202
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIFK-GLDSLTNVDLRGNAFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Score = 47.8 bits (112), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 36/116 (31%), Positives = 64/116 (55%), Gaps = 11/116 (9%)
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
+ +LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NN
Sbjct 38 VISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
I+ + H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 41.6 bits (96), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 34/119 (29%), Positives = 54/119 (45%), Gaps = 10/119 (8%)
Query 457 NIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
++ + + + +++ SF PSLQ L+ + + S F L +L L + NN
Sbjct 37 DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENN 94
Query 517 NIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
NI +I+ GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 95 NIKSISRHTFRGLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNAFN 145
Score = 37.0 bits (84), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLRRVAL 492
L ++ F + SL + LR A
Sbjct 121 QTLPKDIFKGLDSLTNVDLRGNAF 144
Score = 36.2 bits (82), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 34.7 bits (78), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 24/59 (41%), Positives = 37/59 (63%), Gaps = 2/59 (3%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F L
Sbjct 75 ISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIFKGL 131
Score = 33.5 bits (75), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 67/144 (47%), Gaps = 13/144 (9%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGL-KSLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNAF 144
Query 444 GQELTGQ---EWRGLEN--IFEIY 462
+ + EW G N + +IY
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIY 168
>8hpw_A A Leucine-rich glioma-inactivated protein 1
Length=202
Score = 56.6 bits (135), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIFK-GLDSLTNVDLRGNAFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Score = 47.8 bits (112), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 36/116 (31%), Positives = 64/116 (55%), Gaps = 11/116 (9%)
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
+ +LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NN
Sbjct 38 VISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
I+ + H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 41.6 bits (96), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 34/119 (29%), Positives = 54/119 (45%), Gaps = 10/119 (8%)
Query 457 NIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
++ + + + +++ SF PSLQ L+ + + S F L +L L + NN
Sbjct 37 DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENN 94
Query 517 NIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
NI +I+ GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 95 NIKSISRHTFRGLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNAFN 145
Score = 37.0 bits (84), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLRRVAL 492
L ++ F + SL + LR A
Sbjct 121 QTLPKDIFKGLDSLTNVDLRGNAF 144
Score = 36.2 bits (82), Expect = 0.90, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 34.7 bits (78), Expect = 3.0, Method: Compositional matrix adjust.
Identities = 24/59 (41%), Positives = 37/59 (63%), Gaps = 2/59 (3%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F L
Sbjct 75 ISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIFKGL 131
Score = 33.5 bits (75), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 67/144 (47%), Gaps = 13/144 (9%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGL-KSLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNAF 144
Query 444 GQELTGQ---EWRGLEN--IFEIY 462
+ + EW G N + +IY
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIY 168
>5xjx_D D Protein TOO MANY MOUTHS
Length=433
Score = 58.9 bits (141), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 69/228 (30%), Positives = 97/228 (43%), Gaps = 33/228 (14%)
Query 42 LTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
L +PD+L TN+ VL+L N L +F R+S L SLD+ N ++ P LP
Sbjct 145 LGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFV--LP 202
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L VL+L N L+ T C +L ++ L N + + L+ LDLS+N L
Sbjct 203 ALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRL 262
Query 160 SS--------------------TKLGTQVQ------LENLQELLLSNNKIQALKSEELDI 193
S TK T + L+NL L+LSN IQ + L
Sbjct 263 SGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTR 322
Query 194 FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL-GPSLTEK 240
+SL+ L L N + P F + L L LN+ L GP E+
Sbjct 323 L--NSLRVLHLEGNNLTGEIPLEFRDVKHLSELRLNDNSLTGPVPFER 368
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 75/306 (25%), Positives = 122/306 (40%), Gaps = 43/306 (14%)
Query 280 DLSYNNLNVVGNDSFAWLPQL---EYFFLE----YNNIQHLFSHSLHGLFNVRYL---NL 329
D Y+ + GND A +P + + +E +N+ H+ S S L + +
Sbjct 33 DAVYDIMRATGNDWAAAIPDVCRGRWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDP 92
Query 330 KRSFTKQSIS-------------LASLP-KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMF 375
+RS+ +S++ L P +I F + L+ L + +N G +
Sbjct 93 QRSYVSESLTRLKHLKALFFYRCLGRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDEL 152
Query 376 TGLINLKYLSLS------------NSFTSLRTLT------NETFVSLAHSPLHILNLTKN 417
L NLK L L N F+ LR+L + L +L+L +N
Sbjct 153 GNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQN 212
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + G L +DL N + + + L + + LSYN+ +S
Sbjct 213 LLTGPVPPTLTSCGSLIKIDLSRNRVTGPIP-ESINRLNQLVLLDLSYNRLSGPFPSSLQ 271
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDL 537
+ SLQ LML+ + + F+ L+NL IL LSN NI L L L +L L
Sbjct 272 GLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
Query 538 QHNNLA 543
+ NNL
Sbjct 332 EGNNLT 337
Score = 35.0 bits (79), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 62/240 (26%), Positives = 97/240 (40%), Gaps = 41/240 (17%)
Query 400 TFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIF 459
F+ S L L L +N D L +L+VLDL N +
Sbjct 125 AFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGS------------- 171
Query 460 EIYLSYNKY-----LQLTRNSFA------LVPSLQRLMLRRVALKNVDSSPSP--FQPLR 506
I LS+N++ L L+ N ++P+L L L +N+ + P P
Sbjct 172 -IPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLN----QNLLTGPVPPTLTSCG 226
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+L +DLS N + + + L +L +LDL +N L+ + + L+GL+ L
Sbjct 227 SLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRLSGPFPSS--------LQGLNSLQA 278
Query 567 LNLESNG--FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
L L+ N IP FK L L I+ L N+ SL+ L+L+ N +T
Sbjct 279 LMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHLEGNNLTG 338
Score = 35.0 bits (79), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 14/126 (11%)
Query 554 PIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLNNLN-TLPASVFNNQVS 611
P + + S L L L NGF IP E+ +L LK++DL N+LN ++P S FN
Sbjct 124 PAFLGRLGSSLQTLVLRENGFLGPIPDEL-GNLTNLKVLDLHKNHLNGSIPLS-FNRFSG 181
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN-------PFDCTCESIAWFVNWINET 664
L+SL+L N +T PA L+ LD+ N P +C S+ N
Sbjct 182 LRSLDLSGNRLTGSIPGFVLPA---LSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 665 HTNIPE 670
IPE
Sbjct 239 TGPIPE 244
Score = 35.0 bits (79), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 65/251 (26%), Positives = 103/251 (41%), Gaps = 22/251 (9%)
Query 64 RRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCT 123
+R+PA S L +L + N P+ L LKVL+L N L+ +F +
Sbjct 121 QRIPAFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFS 180
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
L L L N + + P L LDL+ N L+ T +L ++ LS N++
Sbjct 181 GLRSLDLSGNRL--TGSIPGFVLPALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL-NNVQLGPSLTEKLC 242
E ++ + L L+LS N++ P + L L L N + ++ E
Sbjct 239 TGPIPESINRL--NQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAF 296
Query 243 LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
L N I LS +N Q S + T + +L +L L NNL +P
Sbjct 297 KGLKNLMILVLSNTNIQGSIPKSLT----RLNSLRVLHLEGNNLT-------GEIP---- 341
Query 303 FFLEYNNIQHL 313
LE+ +++HL
Sbjct 342 --LEFRDVKHL 350
Score = 34.7 bits (78), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 61/216 (28%), Positives = 93/216 (43%), Gaps = 16/216 (7%)
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+LQ L+L N +EL N LK L+L N + P F+ L L L+
Sbjct 132 SSLQTLVLRENGFLGPIPDELGNLTN--LKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSG 189
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
+L S+ + L+ L L+ + L+ T +L +DLS N +
Sbjct 190 NRLTGSIPGFVLPALSV-----LDLNQNLLTGPVPPTLT--SCGSLIKIDLSRNRVTGPI 242
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+S L QL L YN + F SL GL +++ L LK + TK S + I + +
Sbjct 243 PESINRLNQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGN-TKFSTT------IPENA 295
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
F+ LK L L + + +I G T L +L+ L L
Sbjct 296 FKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
>5xjx_G J Protein TOO MANY MOUTHS
Length=433
Score = 58.9 bits (141), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 69/228 (30%), Positives = 97/228 (43%), Gaps = 33/228 (14%)
Query 42 LTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
L +PD+L TN+ VL+L N L +F R+S L SLD+ N ++ P LP
Sbjct 145 LGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFV--LP 202
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L VL+L N L+ T C +L ++ L N + + L+ LDLS+N L
Sbjct 203 ALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRL 262
Query 160 SS--------------------TKLGTQVQ------LENLQELLLSNNKIQALKSEELDI 193
S TK T + L+NL L+LSN IQ + L
Sbjct 263 SGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTR 322
Query 194 FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL-GPSLTEK 240
+SL+ L L N + P F + L L LN+ L GP E+
Sbjct 323 L--NSLRVLHLEGNNLTGEIPLEFRDVKHLSELRLNDNSLTGPVPFER 368
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 75/306 (25%), Positives = 122/306 (40%), Gaps = 43/306 (14%)
Query 280 DLSYNNLNVVGNDSFAWLPQL---EYFFLE----YNNIQHLFSHSLHGLFNVRYL---NL 329
D Y+ + GND A +P + + +E +N+ H+ S S L + +
Sbjct 33 DAVYDIMRATGNDWAAAIPDVCRGRWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDP 92
Query 330 KRSFTKQSIS-------------LASLP-KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMF 375
+RS+ +S++ L P +I F + L+ L + +N G +
Sbjct 93 QRSYVSESLTRLKHLKALFFYRCLGRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDEL 152
Query 376 TGLINLKYLSLS------------NSFTSLRTLT------NETFVSLAHSPLHILNLTKN 417
L NLK L L N F+ LR+L + L +L+L +N
Sbjct 153 GNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQN 212
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + G L +DL N + + + L + + LSYN+ +S
Sbjct 213 LLTGPVPPTLTSCGSLIKIDLSRNRVTGPIP-ESINRLNQLVLLDLSYNRLSGPFPSSLQ 271
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDL 537
+ SLQ LML+ + + F+ L+NL IL LSN NI L L L +L L
Sbjct 272 GLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
Query 538 QHNNLA 543
+ NNL
Sbjct 332 EGNNLT 337
Score = 35.0 bits (79), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 62/240 (26%), Positives = 97/240 (40%), Gaps = 41/240 (17%)
Query 400 TFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIF 459
F+ S L L L +N D L +L+VLDL N +
Sbjct 125 AFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGS------------- 171
Query 460 EIYLSYNKY-----LQLTRNSFA------LVPSLQRLMLRRVALKNVDSSPSP--FQPLR 506
I LS+N++ L L+ N ++P+L L L +N+ + P P
Sbjct 172 -IPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLN----QNLLTGPVPPTLTSCG 226
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+L +DLS N + + + L +L +LDL +N L+ + + L+GL+ L
Sbjct 227 SLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRLSGPFPSS--------LQGLNSLQA 278
Query 567 LNLESNG--FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
L L+ N IP FK L L I+ L N+ SL+ L+L+ N +T
Sbjct 279 LMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHLEGNNLTG 338
Score = 35.0 bits (79), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 14/126 (11%)
Query 554 PIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLNNLN-TLPASVFNNQVS 611
P + + S L L L NGF IP E+ +L LK++DL N+LN ++P S FN
Sbjct 124 PAFLGRLGSSLQTLVLRENGFLGPIPDEL-GNLTNLKVLDLHKNHLNGSIPLS-FNRFSG 181
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN-------PFDCTCESIAWFVNWINET 664
L+SL+L N +T PA L+ LD+ N P +C S+ N
Sbjct 182 LRSLDLSGNRLTGSIPGFVLPA---LSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 665 HTNIPE 670
IPE
Sbjct 239 TGPIPE 244
Score = 35.0 bits (79), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 65/251 (26%), Positives = 103/251 (41%), Gaps = 22/251 (9%)
Query 64 RRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCT 123
+R+PA S L +L + N P+ L LKVL+L N L+ +F +
Sbjct 121 QRIPAFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFS 180
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
L L L N + + P L LDL+ N L+ T +L ++ LS N++
Sbjct 181 GLRSLDLSGNRL--TGSIPGFVLPALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL-NNVQLGPSLTEKLC 242
E ++ + L L+LS N++ P + L L L N + ++ E
Sbjct 239 TGPIPESINRL--NQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAF 296
Query 243 LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
L N I LS +N Q S + T + +L +L L NNL +P
Sbjct 297 KGLKNLMILVLSNTNIQGSIPKSLT----RLNSLRVLHLEGNNLT-------GEIP---- 341
Query 303 FFLEYNNIQHL 313
LE+ +++HL
Sbjct 342 --LEFRDVKHL 350
Score = 34.7 bits (78), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 61/216 (28%), Positives = 93/216 (43%), Gaps = 16/216 (7%)
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+LQ L+L N +EL N LK L+L N + P F+ L L L+
Sbjct 132 SSLQTLVLRENGFLGPIPDELGNLTN--LKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSG 189
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
+L S+ + L+ L L+ + L+ T +L +DLS N +
Sbjct 190 NRLTGSIPGFVLPALSV-----LDLNQNLLTGPVPPTLT--SCGSLIKIDLSRNRVTGPI 242
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+S L QL L YN + F SL GL +++ L LK + TK S + I + +
Sbjct 243 PESINRLNQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGN-TKFSTT------IPENA 295
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
F+ LK L L + + +I G T L +L+ L L
Sbjct 296 FKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
>5xjx_F H Protein TOO MANY MOUTHS
Length=433
Score = 58.9 bits (141), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 69/228 (30%), Positives = 97/228 (43%), Gaps = 33/228 (14%)
Query 42 LTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
L +PD+L TN+ VL+L N L +F R+S L SLD+ N ++ P LP
Sbjct 145 LGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFV--LP 202
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L VL+L N L+ T C +L ++ L N + + L+ LDLS+N L
Sbjct 203 ALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRL 262
Query 160 SS--------------------TKLGTQVQ------LENLQELLLSNNKIQALKSEELDI 193
S TK T + L+NL L+LSN IQ + L
Sbjct 263 SGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTR 322
Query 194 FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL-GPSLTEK 240
+SL+ L L N + P F + L L LN+ L GP E+
Sbjct 323 L--NSLRVLHLEGNNLTGEIPLEFRDVKHLSELRLNDNSLTGPVPFER 368
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 75/306 (25%), Positives = 122/306 (40%), Gaps = 43/306 (14%)
Query 280 DLSYNNLNVVGNDSFAWLPQL---EYFFLE----YNNIQHLFSHSLHGLFNVRYL---NL 329
D Y+ + GND A +P + + +E +N+ H+ S S L + +
Sbjct 33 DAVYDIMRATGNDWAAAIPDVCRGRWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDP 92
Query 330 KRSFTKQSIS-------------LASLP-KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMF 375
+RS+ +S++ L P +I F + L+ L + +N G +
Sbjct 93 QRSYVSESLTRLKHLKALFFYRCLGRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDEL 152
Query 376 TGLINLKYLSLS------------NSFTSLRTLT------NETFVSLAHSPLHILNLTKN 417
L NLK L L N F+ LR+L + L +L+L +N
Sbjct 153 GNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQN 212
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + G L +DL N + + + L + + LSYN+ +S
Sbjct 213 LLTGPVPPTLTSCGSLIKIDLSRNRVTGPIP-ESINRLNQLVLLDLSYNRLSGPFPSSLQ 271
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDL 537
+ SLQ LML+ + + F+ L+NL IL LSN NI L L L +L L
Sbjct 272 GLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
Query 538 QHNNLA 543
+ NNL
Sbjct 332 EGNNLT 337
Score = 35.0 bits (79), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 62/240 (26%), Positives = 97/240 (40%), Gaps = 41/240 (17%)
Query 400 TFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIF 459
F+ S L L L +N D L +L+VLDL N +
Sbjct 125 AFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGS------------- 171
Query 460 EIYLSYNKY-----LQLTRNSFA------LVPSLQRLMLRRVALKNVDSSPSP--FQPLR 506
I LS+N++ L L+ N ++P+L L L +N+ + P P
Sbjct 172 -IPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLN----QNLLTGPVPPTLTSCG 226
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+L +DLS N + + + L +L +LDL +N L+ + + L+GL+ L
Sbjct 227 SLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRLSGPFPSS--------LQGLNSLQA 278
Query 567 LNLESNG--FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
L L+ N IP FK L L I+ L N+ SL+ L+L+ N +T
Sbjct 279 LMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHLEGNNLTG 338
Score = 35.0 bits (79), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 14/126 (11%)
Query 554 PIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLNNLN-TLPASVFNNQVS 611
P + + S L L L NGF IP E+ +L LK++DL N+LN ++P S FN
Sbjct 124 PAFLGRLGSSLQTLVLRENGFLGPIPDEL-GNLTNLKVLDLHKNHLNGSIPLS-FNRFSG 181
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN-------PFDCTCESIAWFVNWINET 664
L+SL+L N +T PA L+ LD+ N P +C S+ N
Sbjct 182 LRSLDLSGNRLTGSIPGFVLPA---LSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 665 HTNIPE 670
IPE
Sbjct 239 TGPIPE 244
Score = 35.0 bits (79), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 65/251 (26%), Positives = 103/251 (41%), Gaps = 22/251 (9%)
Query 64 RRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCT 123
+R+PA S L +L + N P+ L LKVL+L N L+ +F +
Sbjct 121 QRIPAFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFS 180
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
L L L N + + P L LDL+ N L+ T +L ++ LS N++
Sbjct 181 GLRSLDLSGNRL--TGSIPGFVLPALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL-NNVQLGPSLTEKLC 242
E ++ + L L+LS N++ P + L L L N + ++ E
Sbjct 239 TGPIPESINRL--NQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAF 296
Query 243 LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
L N I LS +N Q S + T + +L +L L NNL +P
Sbjct 297 KGLKNLMILVLSNTNIQGSIPKSLT----RLNSLRVLHLEGNNLT-------GEIP---- 341
Query 303 FFLEYNNIQHL 313
LE+ +++HL
Sbjct 342 --LEFRDVKHL 350
Score = 34.7 bits (78), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 61/216 (28%), Positives = 93/216 (43%), Gaps = 16/216 (7%)
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+LQ L+L N +EL N LK L+L N + P F+ L L L+
Sbjct 132 SSLQTLVLRENGFLGPIPDELGNLTN--LKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSG 189
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
+L S+ + L+ L L+ + L+ T +L +DLS N +
Sbjct 190 NRLTGSIPGFVLPALSV-----LDLNQNLLTGPVPPTLT--SCGSLIKIDLSRNRVTGPI 242
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+S L QL L YN + F SL GL +++ L LK + TK S + I + +
Sbjct 243 PESINRLNQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGN-TKFSTT------IPENA 295
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
F+ LK L L + + +I G T L +L+ L L
Sbjct 296 FKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
>5xjx_E L Protein TOO MANY MOUTHS
Length=433
Score = 58.9 bits (141), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 69/228 (30%), Positives = 97/228 (43%), Gaps = 33/228 (14%)
Query 42 LTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
L +PD+L TN+ VL+L N L +F R+S L SLD+ N ++ P LP
Sbjct 145 LGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFV--LP 202
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L VL+L N L+ T C +L ++ L N + + L+ LDLS+N L
Sbjct 203 ALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRL 262
Query 160 SS--------------------TKLGTQVQ------LENLQELLLSNNKIQALKSEELDI 193
S TK T + L+NL L+LSN IQ + L
Sbjct 263 SGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTR 322
Query 194 FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL-GPSLTEK 240
+SL+ L L N + P F + L L LN+ L GP E+
Sbjct 323 L--NSLRVLHLEGNNLTGEIPLEFRDVKHLSELRLNDNSLTGPVPFER 368
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 75/306 (25%), Positives = 122/306 (40%), Gaps = 43/306 (14%)
Query 280 DLSYNNLNVVGNDSFAWLPQL---EYFFLE----YNNIQHLFSHSLHGLFNVRYL---NL 329
D Y+ + GND A +P + + +E +N+ H+ S S L + +
Sbjct 33 DAVYDIMRATGNDWAAAIPDVCRGRWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDP 92
Query 330 KRSFTKQSIS-------------LASLP-KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMF 375
+RS+ +S++ L P +I F + L+ L + +N G +
Sbjct 93 QRSYVSESLTRLKHLKALFFYRCLGRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDEL 152
Query 376 TGLINLKYLSLS------------NSFTSLRTLT------NETFVSLAHSPLHILNLTKN 417
L NLK L L N F+ LR+L + L +L+L +N
Sbjct 153 GNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQN 212
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + G L +DL N + + + L + + LSYN+ +S
Sbjct 213 LLTGPVPPTLTSCGSLIKIDLSRNRVTGPIP-ESINRLNQLVLLDLSYNRLSGPFPSSLQ 271
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDL 537
+ SLQ LML+ + + F+ L+NL IL LSN NI L L L +L L
Sbjct 272 GLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
Query 538 QHNNLA 543
+ NNL
Sbjct 332 EGNNLT 337
Score = 35.0 bits (79), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 62/240 (26%), Positives = 97/240 (40%), Gaps = 41/240 (17%)
Query 400 TFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIF 459
F+ S L L L +N D L +L+VLDL N +
Sbjct 125 AFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGS------------- 171
Query 460 EIYLSYNKY-----LQLTRNSFA------LVPSLQRLMLRRVALKNVDSSPSP--FQPLR 506
I LS+N++ L L+ N ++P+L L L +N+ + P P
Sbjct 172 -IPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLN----QNLLTGPVPPTLTSCG 226
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+L +DLS N + + + L +L +LDL +N L+ + + L+GL+ L
Sbjct 227 SLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRLSGPFPSS--------LQGLNSLQA 278
Query 567 LNLESNG--FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
L L+ N IP FK L L I+ L N+ SL+ L+L+ N +T
Sbjct 279 LMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHLEGNNLTG 338
Score = 35.0 bits (79), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 14/126 (11%)
Query 554 PIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLNNLN-TLPASVFNNQVS 611
P + + S L L L NGF IP E+ +L LK++DL N+LN ++P S FN
Sbjct 124 PAFLGRLGSSLQTLVLRENGFLGPIPDEL-GNLTNLKVLDLHKNHLNGSIPLS-FNRFSG 181
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN-------PFDCTCESIAWFVNWINET 664
L+SL+L N +T PA L+ LD+ N P +C S+ N
Sbjct 182 LRSLDLSGNRLTGSIPGFVLPA---LSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 665 HTNIPE 670
IPE
Sbjct 239 TGPIPE 244
Score = 35.0 bits (79), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 65/251 (26%), Positives = 103/251 (41%), Gaps = 22/251 (9%)
Query 64 RRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCT 123
+R+PA S L +L + N P+ L LKVL+L N L+ +F +
Sbjct 121 QRIPAFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFS 180
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
L L L N + + P L LDL+ N L+ T +L ++ LS N++
Sbjct 181 GLRSLDLSGNRL--TGSIPGFVLPALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL-NNVQLGPSLTEKLC 242
E ++ + L L+LS N++ P + L L L N + ++ E
Sbjct 239 TGPIPESINRL--NQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAF 296
Query 243 LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
L N I LS +N Q S + T + +L +L L NNL +P
Sbjct 297 KGLKNLMILVLSNTNIQGSIPKSLT----RLNSLRVLHLEGNNLT-------GEIP---- 341
Query 303 FFLEYNNIQHL 313
LE+ +++HL
Sbjct 342 --LEFRDVKHL 350
Score = 34.7 bits (78), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 61/216 (28%), Positives = 93/216 (43%), Gaps = 16/216 (7%)
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+LQ L+L N +EL N LK L+L N + P F+ L L L+
Sbjct 132 SSLQTLVLRENGFLGPIPDELGNLTN--LKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSG 189
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
+L S+ + L+ L L+ + L+ T +L +DLS N +
Sbjct 190 NRLTGSIPGFVLPALSV-----LDLNQNLLTGPVPPTLT--SCGSLIKIDLSRNRVTGPI 242
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+S L QL L YN + F SL GL +++ L LK + TK S + I + +
Sbjct 243 PESINRLNQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGN-TKFSTT------IPENA 295
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
F+ LK L L + + +I G T L +L+ L L
Sbjct 296 FKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
>5xjx_C F Protein TOO MANY MOUTHS
Length=433
Score = 58.9 bits (141), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 69/228 (30%), Positives = 97/228 (43%), Gaps = 33/228 (14%)
Query 42 LTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
L +PD+L TN+ VL+L N L +F R+S L SLD+ N ++ P LP
Sbjct 145 LGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFV--LP 202
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L VL+L N L+ T C +L ++ L N + + L+ LDLS+N L
Sbjct 203 ALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRL 262
Query 160 SS--------------------TKLGTQVQ------LENLQELLLSNNKIQALKSEELDI 193
S TK T + L+NL L+LSN IQ + L
Sbjct 263 SGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTR 322
Query 194 FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL-GPSLTEK 240
+SL+ L L N + P F + L L LN+ L GP E+
Sbjct 323 L--NSLRVLHLEGNNLTGEIPLEFRDVKHLSELRLNDNSLTGPVPFER 368
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 75/306 (25%), Positives = 122/306 (40%), Gaps = 43/306 (14%)
Query 280 DLSYNNLNVVGNDSFAWLPQL---EYFFLE----YNNIQHLFSHSLHGLFNVRYL---NL 329
D Y+ + GND A +P + + +E +N+ H+ S S L + +
Sbjct 33 DAVYDIMRATGNDWAAAIPDVCRGRWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDP 92
Query 330 KRSFTKQSIS-------------LASLP-KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMF 375
+RS+ +S++ L P +I F + L+ L + +N G +
Sbjct 93 QRSYVSESLTRLKHLKALFFYRCLGRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDEL 152
Query 376 TGLINLKYLSLS------------NSFTSLRTLT------NETFVSLAHSPLHILNLTKN 417
L NLK L L N F+ LR+L + L +L+L +N
Sbjct 153 GNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQN 212
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + G L +DL N + + + L + + LSYN+ +S
Sbjct 213 LLTGPVPPTLTSCGSLIKIDLSRNRVTGPIP-ESINRLNQLVLLDLSYNRLSGPFPSSLQ 271
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDL 537
+ SLQ LML+ + + F+ L+NL IL LSN NI L L L +L L
Sbjct 272 GLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
Query 538 QHNNLA 543
+ NNL
Sbjct 332 EGNNLT 337
Score = 35.0 bits (79), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 62/240 (26%), Positives = 97/240 (40%), Gaps = 41/240 (17%)
Query 400 TFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIF 459
F+ S L L L +N D L +L+VLDL N +
Sbjct 125 AFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGS------------- 171
Query 460 EIYLSYNKY-----LQLTRNSFA------LVPSLQRLMLRRVALKNVDSSPSP--FQPLR 506
I LS+N++ L L+ N ++P+L L L +N+ + P P
Sbjct 172 -IPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLN----QNLLTGPVPPTLTSCG 226
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+L +DLS N + + + L +L +LDL +N L+ + + L+GL+ L
Sbjct 227 SLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRLSGPFPSS--------LQGLNSLQA 278
Query 567 LNLESNG--FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
L L+ N IP FK L L I+ L N+ SL+ L+L+ N +T
Sbjct 279 LMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHLEGNNLTG 338
Score = 35.0 bits (79), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 14/126 (11%)
Query 554 PIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLNNLN-TLPASVFNNQVS 611
P + + S L L L NGF IP E+ +L LK++DL N+LN ++P S FN
Sbjct 124 PAFLGRLGSSLQTLVLRENGFLGPIPDEL-GNLTNLKVLDLHKNHLNGSIPLS-FNRFSG 181
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN-------PFDCTCESIAWFVNWINET 664
L+SL+L N +T PA L+ LD+ N P +C S+ N
Sbjct 182 LRSLDLSGNRLTGSIPGFVLPA---LSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 665 HTNIPE 670
IPE
Sbjct 239 TGPIPE 244
Score = 35.0 bits (79), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 65/251 (26%), Positives = 103/251 (41%), Gaps = 22/251 (9%)
Query 64 RRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCT 123
+R+PA S L +L + N P+ L LKVL+L N L+ +F +
Sbjct 121 QRIPAFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFS 180
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
L L L N + + P L LDL+ N L+ T +L ++ LS N++
Sbjct 181 GLRSLDLSGNRL--TGSIPGFVLPALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL-NNVQLGPSLTEKLC 242
E ++ + L L+LS N++ P + L L L N + ++ E
Sbjct 239 TGPIPESINRL--NQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAF 296
Query 243 LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
L N I LS +N Q S + T + +L +L L NNL +P
Sbjct 297 KGLKNLMILVLSNTNIQGSIPKSLT----RLNSLRVLHLEGNNLT-------GEIP---- 341
Query 303 FFLEYNNIQHL 313
LE+ +++HL
Sbjct 342 --LEFRDVKHL 350
Score = 34.7 bits (78), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 61/216 (28%), Positives = 93/216 (43%), Gaps = 16/216 (7%)
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+LQ L+L N +EL N LK L+L N + P F+ L L L+
Sbjct 132 SSLQTLVLRENGFLGPIPDELGNLTN--LKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSG 189
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
+L S+ + L+ L L+ + L+ T +L +DLS N +
Sbjct 190 NRLTGSIPGFVLPALSV-----LDLNQNLLTGPVPPTLT--SCGSLIKIDLSRNRVTGPI 242
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+S L QL L YN + F SL GL +++ L LK + TK S + I + +
Sbjct 243 PESINRLNQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGN-TKFSTT------IPENA 295
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
F+ LK L L + + +I G T L +L+ L L
Sbjct 296 FKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
>5xjx_A C Protein TOO MANY MOUTHS
Length=433
Score = 58.9 bits (141), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 69/228 (30%), Positives = 97/228 (43%), Gaps = 33/228 (14%)
Query 42 LTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
L +PD+L TN+ VL+L N L +F R+S L SLD+ N ++ P LP
Sbjct 145 LGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFV--LP 202
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L VL+L N L+ T C +L ++ L N + + L+ LDLS+N L
Sbjct 203 ALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRL 262
Query 160 SS--------------------TKLGTQVQ------LENLQELLLSNNKIQALKSEELDI 193
S TK T + L+NL L+LSN IQ + L
Sbjct 263 SGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTR 322
Query 194 FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL-GPSLTEK 240
+SL+ L L N + P F + L L LN+ L GP E+
Sbjct 323 L--NSLRVLHLEGNNLTGEIPLEFRDVKHLSELRLNDNSLTGPVPFER 368
Score = 49.7 bits (117), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 75/306 (25%), Positives = 122/306 (40%), Gaps = 43/306 (14%)
Query 280 DLSYNNLNVVGNDSFAWLPQL---EYFFLE----YNNIQHLFSHSLHGLFNVRYL---NL 329
D Y+ + GND A +P + + +E +N+ H+ S S L + +
Sbjct 33 DAVYDIMRATGNDWAAAIPDVCRGRWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDP 92
Query 330 KRSFTKQSIS-------------LASLP-KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMF 375
+RS+ +S++ L P +I F + L+ L + +N G +
Sbjct 93 QRSYVSESLTRLKHLKALFFYRCLGRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDEL 152
Query 376 TGLINLKYLSLS------------NSFTSLRTLT------NETFVSLAHSPLHILNLTKN 417
L NLK L L N F+ LR+L + L +L+L +N
Sbjct 153 GNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQN 212
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + G L +DL N + + + L + + LSYN+ +S
Sbjct 213 LLTGPVPPTLTSCGSLIKIDLSRNRVTGPIP-ESINRLNQLVLLDLSYNRLSGPFPSSLQ 271
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDL 537
+ SLQ LML+ + + F+ L+NL IL LSN NI L L L +L L
Sbjct 272 GLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
Query 538 QHNNLA 543
+ NNL
Sbjct 332 EGNNLT 337
Score = 35.0 bits (79), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 62/240 (26%), Positives = 97/240 (40%), Gaps = 41/240 (17%)
Query 400 TFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIF 459
F+ S L L L +N D L +L+VLDL N +
Sbjct 125 AFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGS------------- 171
Query 460 EIYLSYNKY-----LQLTRNSFA------LVPSLQRLMLRRVALKNVDSSPSP--FQPLR 506
I LS+N++ L L+ N ++P+L L L +N+ + P P
Sbjct 172 -IPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLN----QNLLTGPVPPTLTSCG 226
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+L +DLS N + + + L +L +LDL +N L+ + + L+GL+ L
Sbjct 227 SLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRLSGPFPSS--------LQGLNSLQA 278
Query 567 LNLESNG--FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
L L+ N IP FK L L I+ L N+ SL+ L+L+ N +T
Sbjct 279 LMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHLEGNNLTG 338
Score = 35.0 bits (79), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 14/126 (11%)
Query 554 PIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLNNLN-TLPASVFNNQVS 611
P + + S L L L NGF IP E+ +L LK++DL N+LN ++P S FN
Sbjct 124 PAFLGRLGSSLQTLVLRENGFLGPIPDEL-GNLTNLKVLDLHKNHLNGSIPLS-FNRFSG 181
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN-------PFDCTCESIAWFVNWINET 664
L+SL+L N +T PA L+ LD+ N P +C S+ N
Sbjct 182 LRSLDLSGNRLTGSIPGFVLPA---LSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 665 HTNIPE 670
IPE
Sbjct 239 TGPIPE 244
Score = 35.0 bits (79), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 65/251 (26%), Positives = 103/251 (41%), Gaps = 22/251 (9%)
Query 64 RRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCT 123
+R+PA S L +L + N P+ L LKVL+L N L+ +F +
Sbjct 121 QRIPAFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFS 180
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
L L L N + + P L LDL+ N L+ T +L ++ LS N++
Sbjct 181 GLRSLDLSGNRL--TGSIPGFVLPALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL-NNVQLGPSLTEKLC 242
E ++ + L L+LS N++ P + L L L N + ++ E
Sbjct 239 TGPIPESINRL--NQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAF 296
Query 243 LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
L N I LS +N Q S + T + +L +L L NNL +P
Sbjct 297 KGLKNLMILVLSNTNIQGSIPKSLT----RLNSLRVLHLEGNNLT-------GEIP---- 341
Query 303 FFLEYNNIQHL 313
LE+ +++HL
Sbjct 342 --LEFRDVKHL 350
Score = 34.7 bits (78), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 61/216 (28%), Positives = 93/216 (43%), Gaps = 16/216 (7%)
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+LQ L+L N +EL N LK L+L N + P F+ L L L+
Sbjct 132 SSLQTLVLRENGFLGPIPDELGNLTN--LKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSG 189
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
+L S+ + L+ L L+ + L+ T +L +DLS N +
Sbjct 190 NRLTGSIPGFVLPALSV-----LDLNQNLLTGPVPPTLT--SCGSLIKIDLSRNRVTGPI 242
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+S L QL L YN + F SL GL +++ L LK + TK S + I + +
Sbjct 243 PESINRLNQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGN-TKFSTT------IPENA 295
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
F+ LK L L + + +I G T L +L+ L L
Sbjct 296 FKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
>5xkj_D D Protein TOO MANY MOUTHS
Length=433
Score = 58.5 bits (140), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 69/228 (30%), Positives = 97/228 (43%), Gaps = 33/228 (14%)
Query 42 LTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
L +PD+L TN+ VL+L N L +F R+S L SLD+ N ++ P LP
Sbjct 145 LGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFV--LP 202
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L VL+L N L+ T C +L ++ L N + + L+ LDLS+N L
Sbjct 203 ALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRL 262
Query 160 SS--------------------TKLGTQVQ------LENLQELLLSNNKIQALKSEELDI 193
S TK T + L+NL L+LSN IQ + L
Sbjct 263 SGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTR 322
Query 194 FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL-GPSLTEK 240
+SL+ L L N + P F + L L LN+ L GP E+
Sbjct 323 L--NSLRVLHLEGNNLTGEIPLEFRDVKHLSELRLNDNSLTGPVPFER 368
Score = 49.3 bits (116), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 75/306 (25%), Positives = 122/306 (40%), Gaps = 43/306 (14%)
Query 280 DLSYNNLNVVGNDSFAWLPQL---EYFFLE----YNNIQHLFSHSLHGLFNVRYL---NL 329
D Y+ + GND A +P + + +E +N+ H+ S S L + +
Sbjct 33 DAVYDIMRATGNDWAAAIPDVCRGRWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDP 92
Query 330 KRSFTKQSIS-------------LASLP-KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMF 375
+RS+ +S++ L P +I F + L+ L + +N G +
Sbjct 93 QRSYVSESLTRLKHLKALFFYRCLGRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDEL 152
Query 376 TGLINLKYLSLS------------NSFTSLRTLT------NETFVSLAHSPLHILNLTKN 417
L NLK L L N F+ LR+L + L +L+L +N
Sbjct 153 GNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQN 212
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + G L +DL N + + + L + + LSYN+ +S
Sbjct 213 LLTGPVPPTLTSCGSLIKIDLSRNRVTGPIP-ESINRLNQLVLLDLSYNRLSGPFPSSLQ 271
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDL 537
+ SLQ LML+ + + F+ L+NL IL LSN NI L L L +L L
Sbjct 272 GLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
Query 538 QHNNLA 543
+ NNL
Sbjct 332 EGNNLT 337
Score = 35.0 bits (79), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 14/126 (11%)
Query 554 PIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLNNLN-TLPASVFNNQVS 611
P + + S L L L NGF IP E+ +L LK++DL N+LN ++P S FN
Sbjct 124 PAFLGRLGSSLQTLVLRENGFLGPIPDEL-GNLTNLKVLDLHKNHLNGSIPLS-FNRFSG 181
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN-------PFDCTCESIAWFVNWINET 664
L+SL+L N +T PA L+ LD+ N P +C S+ N
Sbjct 182 LRSLDLSGNRLTGSIPGFVLPA---LSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 665 HTNIPE 670
IPE
Sbjct 239 TGPIPE 244
Score = 35.0 bits (79), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 62/240 (26%), Positives = 97/240 (40%), Gaps = 41/240 (17%)
Query 400 TFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIF 459
F+ S L L L +N D L +L+VLDL N +
Sbjct 125 AFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGS------------- 171
Query 460 EIYLSYNKY-----LQLTRNSFA------LVPSLQRLMLRRVALKNVDSSPSP--FQPLR 506
I LS+N++ L L+ N ++P+L L L +N+ + P P
Sbjct 172 -IPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLN----QNLLTGPVPPTLTSCG 226
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+L +DLS N + + + L +L +LDL +N L+ + + L+GL+ L
Sbjct 227 SLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRLSGPFPSS--------LQGLNSLQA 278
Query 567 LNLESNG--FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
L L+ N IP FK L L I+ L N+ SL+ L+L+ N +T
Sbjct 279 LMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHLEGNNLTG 338
Score = 34.7 bits (78), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 65/251 (26%), Positives = 103/251 (41%), Gaps = 22/251 (9%)
Query 64 RRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCT 123
+R+PA S L +L + N P+ L LKVL+L N L+ +F +
Sbjct 121 QRIPAFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFS 180
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
L L L N + + P L LDL+ N L+ T +L ++ LS N++
Sbjct 181 GLRSLDLSGNRL--TGSIPGFVLPALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL-NNVQLGPSLTEKLC 242
E ++ + L L+LS N++ P + L L L N + ++ E
Sbjct 239 TGPIPESINRL--NQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAF 296
Query 243 LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
L N I LS +N Q S + T + +L +L L NNL +P
Sbjct 297 KGLKNLMILVLSNTNIQGSIPKSLT----RLNSLRVLHLEGNNLT-------GEIP---- 341
Query 303 FFLEYNNIQHL 313
LE+ +++HL
Sbjct 342 --LEFRDVKHL 350
Score = 34.7 bits (78), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 61/216 (28%), Positives = 93/216 (43%), Gaps = 16/216 (7%)
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+LQ L+L N +EL N LK L+L N + P F+ L L L+
Sbjct 132 SSLQTLVLRENGFLGPIPDELGNLTN--LKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSG 189
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
+L S+ + L+ L L+ + L+ T +L +DLS N +
Sbjct 190 NRLTGSIPGFVLPALSV-----LDLNQNLLTGPVPPTLT--SCGSLIKIDLSRNRVTGPI 242
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+S L QL L YN + F SL GL +++ L LK + TK S + I + +
Sbjct 243 PESINRLNQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGN-TKFSTT------IPENA 295
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
F+ LK L L + + +I G T L +L+ L L
Sbjct 296 FKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
>5xkj_A C Protein TOO MANY MOUTHS
Length=433
Score = 58.5 bits (140), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 69/228 (30%), Positives = 97/228 (43%), Gaps = 33/228 (14%)
Query 42 LTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
L +PD+L TN+ VL+L N L +F R+S L SLD+ N ++ P LP
Sbjct 145 LGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFV--LP 202
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L VL+L N L+ T C +L ++ L N + + L+ LDLS+N L
Sbjct 203 ALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRL 262
Query 160 SS--------------------TKLGTQVQ------LENLQELLLSNNKIQALKSEELDI 193
S TK T + L+NL L+LSN IQ + L
Sbjct 263 SGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTR 322
Query 194 FANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL-GPSLTEK 240
+SL+ L L N + P F + L L LN+ L GP E+
Sbjct 323 L--NSLRVLHLEGNNLTGEIPLEFRDVKHLSELRLNDNSLTGPVPFER 368
Score = 49.3 bits (116), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 75/306 (25%), Positives = 122/306 (40%), Gaps = 43/306 (14%)
Query 280 DLSYNNLNVVGNDSFAWLPQL---EYFFLE----YNNIQHLFSHSLHGLFNVRYL---NL 329
D Y+ + GND A +P + + +E +N+ H+ S S L + +
Sbjct 33 DAVYDIMRATGNDWAAAIPDVCRGRWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDP 92
Query 330 KRSFTKQSIS-------------LASLP-KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMF 375
+RS+ +S++ L P +I F + L+ L + +N G +
Sbjct 93 QRSYVSESLTRLKHLKALFFYRCLGRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDEL 152
Query 376 TGLINLKYLSLS------------NSFTSLRTLT------NETFVSLAHSPLHILNLTKN 417
L NLK L L N F+ LR+L + L +L+L +N
Sbjct 153 GNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQN 212
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + G L +DL N + + + L + + LSYN+ +S
Sbjct 213 LLTGPVPPTLTSCGSLIKIDLSRNRVTGPIP-ESINRLNQLVLLDLSYNRLSGPFPSSLQ 271
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDL 537
+ SLQ LML+ + + F+ L+NL IL LSN NI L L L +L L
Sbjct 272 GLNSLQALMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
Query 538 QHNNLA 543
+ NNL
Sbjct 332 EGNNLT 337
Score = 35.0 bits (79), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 14/126 (11%)
Query 554 PIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLNNLN-TLPASVFNNQVS 611
P + + S L L L NGF IP E+ +L LK++DL N+LN ++P S FN
Sbjct 124 PAFLGRLGSSLQTLVLRENGFLGPIPDEL-GNLTNLKVLDLHKNHLNGSIPLS-FNRFSG 181
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN-------PFDCTCESIAWFVNWINET 664
L+SL+L N +T PA L+ LD+ N P +C S+ N
Sbjct 182 LRSLDLSGNRLTGSIPGFVLPA---LSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 665 HTNIPE 670
IPE
Sbjct 239 TGPIPE 244
Score = 35.0 bits (79), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 62/240 (26%), Positives = 97/240 (40%), Gaps = 41/240 (17%)
Query 400 TFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIF 459
F+ S L L L +N D L +L+VLDL N +
Sbjct 125 AFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGS------------- 171
Query 460 EIYLSYNKY-----LQLTRNSFA------LVPSLQRLMLRRVALKNVDSSPSP--FQPLR 506
I LS+N++ L L+ N ++P+L L L +N+ + P P
Sbjct 172 -IPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLN----QNLLTGPVPPTLTSCG 226
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+L +DLS N + + + L +L +LDL +N L+ + + L+GL+ L
Sbjct 227 SLIKIDLSRNRVTGPIPESINRLNQLVLLDLSYNRLSGPFPSS--------LQGLNSLQA 278
Query 567 LNLESNG--FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
L L+ N IP FK L L I+ L N+ SL+ L+L+ N +T
Sbjct 279 LMLKGNTKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHLEGNNLTG 338
Score = 34.7 bits (78), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 65/251 (26%), Positives = 103/251 (41%), Gaps = 22/251 (9%)
Query 64 RRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCT 123
+R+PA S L +L + N P+ L LKVL+L N L+ +F +
Sbjct 121 QRIPAFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFS 180
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
L L L N + + P L LDL+ N L+ T +L ++ LS N++
Sbjct 181 GLRSLDLSGNRL--TGSIPGFVLPALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 238
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL-NNVQLGPSLTEKLC 242
E ++ + L L+LS N++ P + L L L N + ++ E
Sbjct 239 TGPIPESINRL--NQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGNTKFSTTIPENAF 296
Query 243 LELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY 302
L N I LS +N Q S + T + +L +L L NNL +P
Sbjct 297 KGLKNLMILVLSNTNIQGSIPKSLT----RLNSLRVLHLEGNNLT-------GEIP---- 341
Query 303 FFLEYNNIQHL 313
LE+ +++HL
Sbjct 342 --LEFRDVKHL 350
Score = 34.7 bits (78), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 61/216 (28%), Positives = 93/216 (43%), Gaps = 16/216 (7%)
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+LQ L+L N +EL N LK L+L N + P F+ L L L+
Sbjct 132 SSLQTLVLRENGFLGPIPDELGNLTN--LKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSG 189
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
+L S+ + L+ L L+ + L+ T +L +DLS N +
Sbjct 190 NRLTGSIPGFVLPALSV-----LDLNQNLLTGPVPPTLT--SCGSLIKIDLSRNRVTGPI 242
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+S L QL L YN + F SL GL +++ L LK + TK S + I + +
Sbjct 243 PESINRLNQLVLLDLSYNRLSGPFPSSLQGLNSLQALMLKGN-TKFSTT------IPENA 295
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
F+ LK L L + + +I G T L +L+ L L
Sbjct 296 FKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 331
>5y30_A A Leucine-rich glioma-inactivated protein 1
Length=210
Score = 56.6 bits (135), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 73 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 132
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 133 TLPKDIFK-GLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 186
Score = 47.8 bits (112), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 36/116 (31%), Positives = 64/116 (55%), Gaps = 11/116 (9%)
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNN 309
+ +LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NN
Sbjct 49 VISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 106
Query 310 IQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
I+ + H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 107 IKSISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 153
Score = 44.3 bits (103), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 56/120 (47%), Gaps = 10/120 (8%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
P + L R + F P +L +L ++N+ I+DD GL LE L +++
Sbjct 47 PDVISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIEN 104
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN+ + +H +GL L L+L +N +P ++FK L L +DL N+ N
Sbjct 105 NNIKSISRHT--------FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 156
Score = 41.2 bits (95), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 34/119 (29%), Positives = 54/119 (45%), Gaps = 10/119 (8%)
Query 457 NIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN 516
++ + + + +++ SF PSLQ L+ + + S F L +L L + NN
Sbjct 48 DVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENN 105
Query 517 NIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
NI +I+ GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 106 NIKSISRHTFRGLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNSFN 156
Score = 37.0 bits (84), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 26/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 73 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 131
Query 469 LQLTRNSFALVPSLQRLMLR 488
L ++ F + SL + LR
Sbjct 132 QTLPKDIFKGLDSLTNVDLR 151
Score = 36.2 bits (82), Expect = 0.97, Method: Compositional matrix adjust.
Identities = 32/111 (29%), Positives = 54/111 (49%), Gaps = 4/111 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 47 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 106
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQ 208
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 107 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGNS 154
Score = 34.7 bits (78), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 24/59 (41%), Positives = 37/59 (63%), Gaps = 2/59 (3%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F L
Sbjct 86 ISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIFKGL 142
Score = 33.5 bits (75), Expect = 7.4, Method: Compositional matrix adjust.
Identities = 39/144 (27%), Positives = 67/144 (47%), Gaps = 13/144 (9%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 40 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 99
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 100 LFIENN--NIKSISRHTFRGL-KSLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNSF 155
Query 444 GQELTGQ---EWRGLEN--IFEIY 462
+ + EW G N + +IY
Sbjct 156 NCDCKLKWLVEWLGHTNATVEDIY 179
>6ka7_B B repebody
Length=256
Score = 57.4 bits (137), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 46/131 (35%), Positives = 59/131 (45%), Gaps = 0/131 (0%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+T L L NQL+ F + + L L + N + L + KL L LNL HN+
Sbjct 79 TNLTYLELKWNQLQXXXXXVFDKLTNLKELVLNSNQLQSLPDGVFDKLTNLTYLNLAHNQ 138
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
L L D F TNLT L L N +Q + F K L L L N L S G
Sbjct 139 LQSLPDGVFDKLTNLTGLELCGNQLQSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVFXXX 198
Query 171 ENLQELLLSNN 181
+LQ + L +N
Sbjct 199 TSLQYIWLHDN 209
Score = 57.0 bits (136), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 50/158 (32%), Positives = 78/158 (49%), Gaps = 3/158 (2%)
Query 29 TVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS 88
++ +A+ S +K Q LP N+ L L N+L + A + LT L++ +N +
Sbjct 36 SIDQIIANNSDIKSVQGIQYLP-NVRYLALGGNKLHDISA--LKELTNLTYLELKWNQLQ 92
Query 89 KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN 148
+ KL LK L L N+L L D F TNLT L+L N +Q + + F K N
Sbjct 93 XXXXXVFDKLTNLKELVLNSNQLQSLPDGVFDKLTNLTYLNLAHNQLQSLPDGVFDKLTN 152
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQAL 186
L L+L N L S G +L L++L L N+++++
Sbjct 153 LTGLELCGNQLQSLPEGVFDKLTQLKDLRLYQNQLKSV 190
Score = 56.6 bits (135), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 45/122 (37%), Positives = 60/122 (49%), Gaps = 2/122 (2%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
++L L L L+ N+L F TNL EL L SN +Q + + F K NL L+L+
Sbjct 76 KELTNLTYLELKWNQLQXXXXXVFDKLTNLKELVLNSNQLQSLPDGVFDKLTNLTYLNLA 135
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
HN L S G +L NL L L N++Q+L D + LK L L NQ+K G
Sbjct 136 HNQLQSLPDGVFDKLTNLTGLELCGNQLQSLPEGVFDKL--TQLKDLRLYQNQLKSVPDG 193
Query 216 CF 217
F
Sbjct 194 VF 195
Score = 54.7 bits (130), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 36/96 (38%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Query 41 KLTQVPD---DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
+L +PD D TN+T LNL HNQL+ LP F + + LT L++ N + L + K
Sbjct 114 QLQSLPDGVFDKLTNLTYLNLAHNQLQSLPDGVFDKLTNLTGLELCGNQLQSLPEGVFDK 173
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
L LK L L N+L + D F T+L + L N
Sbjct 174 LTQLKDLRLYQNQLKSVPDGVFXXXTSLQYIWLHDN 209
Score = 48.9 bits (115), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 47/152 (31%), Positives = 68/152 (45%), Gaps = 12/152 (8%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P+++ L L L ++ S + L NLT L+L N + + + L L+ L L
Sbjct 56 LPNVRYLALGGNKLHDI----SALKELTNLTYLELKWNQLQXXXXXVFDKLTNLKELVLN 111
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
N L L P L++L LNL N +P VF L L ++L N L
Sbjct 112 SNQLQSL--------PDGVFDKLTNLTYLNLAHNQLQSLPDGVFDKLTNLTGLELCGNQL 163
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+LP VF+ LK L L +N + SV VF
Sbjct 164 QSLPEGVFDKLTQLKDLRLYQNQLKSVPDGVF 195
Score = 35.0 bits (79), Expect = 3.2, Method: Compositional matrix adjust.
Identities = 45/140 (32%), Positives = 63/140 (45%), Gaps = 7/140 (5%)
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+L NL L L N++Q D N LK+L L+SNQ++ G F + L L L
Sbjct 77 ELTNLTYLELKWNQLQXXXXXVFDKLTN--LKELVLNSNQLQSLPDGVFDKLTNLTYLNL 134
Query 229 NNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV 288
+ QL SL + + +L N + L L +QL + F K T L L L N L
Sbjct 135 AHNQL-QSLPDGVFDKLTN--LTGLELCGNQLQSLPEGVF--DKLTQLKDLRLYQNQLKS 189
Query 289 VGNDSFAWLPQLEYFFLEYN 308
V + F L+Y +L N
Sbjct 190 VPDGVFXXXTSLQYIWLHDN 209
>1fyw_A A TOLL-LIKE RECEPTOR 2
Length=177
Score = 55.8 bits (133), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 38/146 (26%), Positives = 75/146 (51%), Gaps = 4/146 (3%)
Query 756 YAAYIIHAYKDKDWVWEHFSSMEKED--QSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
Y A++ ++ +D WV E+ E E+ K L +RDF G + ++ I++SI++S K
Sbjct 6 YDAFVSYSERDAYWV-ENLMVQELENFNPPFKLXLHKRDFIPGKWIIDNIIDSIEKSHKT 64
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
+FV++ + +K K +++ + + ++N D+ IL+ LE I + R + +
Sbjct 65 VFVLSENFVKSEWXK-YELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFXKLRKIMNT 123
Query 874 HCILNWPVQKERIGAFRHKLQVALGS 899
L WP+ + + F L+ A+ S
Sbjct 124 KTYLEWPMDEAQREGFWVNLRAAIKS 149
>7la8_B B O6 variable lymphocyte receptor
Length=173
Score = 55.5 bits (132), Expect = 2e-07, Method: Composition-based stats.
Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 2/102 (2%)
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
L L +N ++ VF L +L + L N L LPA VF+ LK L L +N + S+
Sbjct 35 LWLSNNQLTKLDPGVFDSLTQLTTLYLSNNQLTALPAGVFDKLTQLKELGLDQNQLKSIP 94
Query 627 KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
F +LT + + NP+DC C I + W+ + H++I
Sbjct 95 DGAFA-RLPSLTHVWLHTNPWDCQCTDILYLSGWVAQ-HSSI 134
Score = 54.3 bits (129), Expect = 5e-07, Method: Composition-based stats.
Identities = 32/98 (33%), Positives = 49/98 (50%), Gaps = 0/98 (0%)
Query 36 DCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
+C + VP +P L L++NQL +L F +QLT+L + N ++ L +
Sbjct 15 NCDGARFASVPAAIPITTQRLWLSNNQLTKLDPGVFDSLTQLTTLYLSNNQLTALPAGVF 74
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
KL LK L L N+L + D FA +LT + L +N
Sbjct 75 DKLTQLKELGLDQNQLKSIPDGAFARLPSLTHVWLHTN 112
Score = 37.0 bits (84), Expect = 0.35, Method: Composition-based stats.
Identities = 30/111 (27%), Positives = 46/111 (41%), Gaps = 29/111 (26%)
Query 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSN 257
+ ++L LS+NQ+ + PG F ++ T + L LSN
Sbjct 31 TTQRLWLSNNQLTKLDPGVFDSL---------------------------TQLTTLYLSN 63
Query 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
+QL+ F K T L L L N L + + +FA LP L + +L N
Sbjct 64 NQLTALPAGVF--DKLTQLKELGLDQNQLKSIPDGAFARLPSLTHVWLHTN 112
Score = 36.6 bits (83), Expect = 0.47, Method: Composition-based stats.
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 2/76 (3%)
Query 154 LSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LS+N L+ G L L L LSNN++ AL + D + LK+L L NQ+K
Sbjct 37 LSNNQLTKLDPGVFDSLTQLTTLYLSNNQLTALPAGVFDKL--TQLKELGLDQNQLKSIP 94
Query 214 PGCFHAIGRLFGLFLN 229
G F + L ++L+
Sbjct 95 DGAFARLPSLTHVWLH 110
>7la8_A A O6 variable lymphocyte receptor
Length=173
Score = 55.5 bits (132), Expect = 2e-07, Method: Composition-based stats.
Identities = 33/102 (32%), Positives = 51/102 (50%), Gaps = 2/102 (2%)
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
L L +N ++ VF L +L + L N L LPA VF+ LK L L +N + S+
Sbjct 35 LWLSNNQLTKLDPGVFDSLTQLTTLYLSNNQLTALPAGVFDKLTQLKELGLDQNQLKSIP 94
Query 627 KKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
F +LT + + NP+DC C I + W+ + H++I
Sbjct 95 DGAFA-RLPSLTHVWLHTNPWDCQCTDILYLSGWVAQ-HSSI 134
Score = 54.3 bits (129), Expect = 5e-07, Method: Composition-based stats.
Identities = 32/98 (33%), Positives = 49/98 (50%), Gaps = 0/98 (0%)
Query 36 DCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
+C + VP +P L L++NQL +L F +QLT+L + N ++ L +
Sbjct 15 NCDGARFASVPAAIPITTQRLWLSNNQLTKLDPGVFDSLTQLTTLYLSNNQLTALPAGVF 74
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
KL LK L L N+L + D FA +LT + L +N
Sbjct 75 DKLTQLKELGLDQNQLKSIPDGAFARLPSLTHVWLHTN 112
Score = 37.0 bits (84), Expect = 0.35, Method: Composition-based stats.
Identities = 30/111 (27%), Positives = 46/111 (41%), Gaps = 29/111 (26%)
Query 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSN 257
+ ++L LS+NQ+ + PG F ++ T + L LSN
Sbjct 31 TTQRLWLSNNQLTKLDPGVFDSL---------------------------TQLTTLYLSN 63
Query 258 SQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
+QL+ F K T L L L N L + + +FA LP L + +L N
Sbjct 64 NQLTALPAGVF--DKLTQLKELGLDQNQLKSIPDGAFARLPSLTHVWLHTN 112
Score = 36.6 bits (83), Expect = 0.47, Method: Composition-based stats.
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 2/76 (3%)
Query 154 LSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LS+N L+ G L L L LSNN++ AL + D + LK+L L NQ+K
Sbjct 37 LSNNQLTKLDPGVFDSLTQLTTLYLSNNQLTALPAGVFDKL--TQLKELGLDQNQLKSIP 94
Query 214 PGCFHAIGRLFGLFLN 229
G F + L ++L+
Sbjct 95 DGAFARLPSLTHVWLH 110
>8tzf_A A Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 59.3 bits (142), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 38.5 bits (88), Expect = 0.48, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 35.0 bits (79), Expect = 5.5, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>7li3_A A Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.9 bits (141), Expect = 2e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 133/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H L+L NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTH-----LDLHSNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.4 bits (85), Expect = 0.93, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 35.0 bits (79), Expect = 4.8, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>8u8a_A B Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.4 bits (85), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>8u8a_B C Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.4 bits (85), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>8u7l_B A Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.4 bits (85), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>8u7l_A B Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.4 bits (85), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>8tzh_B A Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.7 bits (86), Expect = 0.79, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 34.3 bits (77), Expect = 8.7, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>8u8b_B B Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.4 bits (85), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>8u8b_A A Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.4 bits (85), Expect = 0.88, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>7li4_A A Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 133/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H L+L NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTH-----LDLHSNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.4 bits (85), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 35.0 bits (79), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>7lht_B B Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 133/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H L+L NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTH-----LDLHSNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.4 bits (85), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 35.0 bits (79), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>7lht_A A Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 133/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H L+L NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTH-----LDLHSNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.4 bits (85), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 35.0 bits (79), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>4p8s_A A Reticulon-4 receptor-like 2
Length=282
Score = 57.0 bits (136), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 61/220 (28%), Positives = 88/220 (40%), Gaps = 38/220 (17%)
Query 499 PSPFQPLRNLTILDLSNN-NIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF 557
P F+ L+ L LDL +N ++ ++ D +GLE+L+ L L L+ L P
Sbjct 71 PGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSL--------PGNI 122
Query 558 LKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
+GL L L L+ N + ++F DL L + L N L L VF SL L L
Sbjct 123 FRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLL 182
Query 618 QKNLITSVEKKVF--------------------GPAFRNLTELD---MRFNPFDCTCESI 654
N + V + F G A +L L+ + NP+ C C +
Sbjct 183 HGNRLQGVHRAAFHGLSRLTILYLFNNSLASLPGEALADLPALEFLRLNANPWACDCRAR 242
Query 655 AWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVR-LFDT 693
+ W + SS C TPP G +R L DT
Sbjct 243 PLWA-WFQRARVS----SSDVTCATPPERQGRDLRTLRDT 277
Score = 55.8 bits (133), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 57/183 (31%), Positives = 82/183 (45%), Gaps = 10/183 (5%)
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
L N +S I F L LE LDLG N + L ++GLE + ++L + L
Sbjct 61 LFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPG 120
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
N F + SLQ L L+ +L ++ F L NL+ L L N + + + + GL L+
Sbjct 121 NIFRGLVSLQYLYLQENSLLHLQD--DLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLD 178
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
L L N L + + A GLS L IL L +N +P E DL L+ + L
Sbjct 179 RLLLHGNRLQGVHRAA--------FHGLSRLTILYLFNNSLASLPGEALADLPALEFLRL 230
Query 594 GLN 596
N
Sbjct 231 NAN 233
Score = 54.3 bits (129), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 65/225 (29%), Positives = 92/225 (41%), Gaps = 12/225 (5%)
Query 19 MLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLT 78
MLC ++ TVS C + VP LP + L L +N +R L F L
Sbjct 5 MLCTCYSSPPTVS-----CQANNFSSVPLSLPPSTQRLFLQNNLIRSLRPGTFG--PNLL 57
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHNE-LSQLSDKTFAFCTNLTELHLMSNSIQK 137
+L + N +S + P + L L+ L+L N L L TF L LHL +
Sbjct 58 TLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSS 117
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN- 196
+ N F +L L L N L + L NL L L N+++ L +F
Sbjct 118 LPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEH---VFRGL 174
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKL 241
SL +L L N+++ FH + RL L+L N L E L
Sbjct 175 GSLDRLLLHGNRLQGVHRAAFHGLSRLTILYLFNNSLASLPGEAL 219
Score = 47.0 bits (110), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 68/212 (32%), Positives = 95/212 (45%), Gaps = 12/212 (6%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L LQ+N + L TF NL L L SN++ I F + L LDL N
Sbjct 32 PSTQRLFLQNNLIRSLRPGTFG--PNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNR 89
Query 159 -LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGC 216
L S + T LE LQ L L ++ +L +IF SL+ L L N +
Sbjct 90 HLRSLEPDTFQGLERLQSLHLYRCQLSSLPG---NIFRGLVSLQYLYLQENSLLHLQDDL 146
Query 217 FHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNL 276
F + L LFL+ +L LTE + L S+ L L ++L F GL + L
Sbjct 147 FADLANLSHLFLHGNRLR-LLTEHVFRGLG--SLDRLLLHGNRLQGVHRAAFHGL--SRL 201
Query 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
T+L L N+L + ++ A LP LE+ L N
Sbjct 202 TILYLFNNSLASLPGEALADLPALEFLRLNAN 233
Score = 45.4 bits (106), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 42/138 (30%), Positives = 70/138 (51%), Gaps = 5/138 (4%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
+FQ L+ L+ L++ + + N+F GL++L+YL L + SL L ++ F LA+ L
Sbjct 98 TFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQEN--SLLHLQDDLFADLAN--L 153
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
L L N++ + F LG L+ L L N + Q + + GL + +YL N
Sbjct 154 SHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRL-QGVHRAAFHGLSRLTILYLFNNSLA 212
Query 470 QLTRNSFALVPSLQRLML 487
L + A +P+L+ L L
Sbjct 213 SLPGEALADLPALEFLRL 230
Score = 45.1 bits (105), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 69/239 (29%), Positives = 104/239 (44%), Gaps = 13/239 (5%)
Query 92 PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
P LC ++ Q N S + + + L L +N I+ ++ F NL+T
Sbjct 4 PMLCTCYSSPPTVSCQANNFSSVP---LSLPPSTQRLFLQNNLIRSLRPGTF--GPNLLT 58
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIK 210
L L N LS+ GT L+ L+EL L +N+ L+S E D F L+ L L Q+
Sbjct 59 LWLFSNNLSTIYPGTFRHLQALEELDLGDNR--HLRSLEPDTFQGLERLQSLHLYRCQLS 116
Query 211 EFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLG 270
F + L L+L L L + L +LAN S +L L ++L + F G
Sbjct 117 SLPGNIFRGLVSLQYLYLQENSLL-HLQDDLFADLANLS--HLFLHGNRLRLLTEHVFRG 173
Query 271 LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
L +L L L N L V +F L +L +L N++ L +L L + +L L
Sbjct 174 LG--SLDRLLLHGNRLQGVHRAAFHGLSRLTILYLFNNSLASLPGEALADLPALEFLRL 230
Score = 37.4 bits (85), Expect = 0.58, Method: Compositional matrix adjust.
Identities = 66/245 (27%), Positives = 102/245 (42%), Gaps = 45/245 (18%)
Query 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSN 257
S ++L L +N I+ PG F GP+L L L +
Sbjct 33 STQRLFLQNNLIRSLRPGTF----------------GPNLL-------------TLWLFS 63
Query 258 SQLSTTSNTTFLGLKWTNLTMLDLSYN-NLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
+ LST TF L+ L LDL N +L + D+F L +L+ L + L +
Sbjct 64 NNLSTIYPGTFRHLQ--ALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGN 121
Query 317 SLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFT 376
GL +++YL L+ + SL + D F L L HL + N + + ++F
Sbjct 122 IFRGLVSLQYLYLQEN---------SLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFR 172
Query 377 GLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVL 436
GL +L L L + L+ + F L+ L IL L N ++ + +A + L LE L
Sbjct 173 GLGSLDRLLLHGN--RLQGVHRAAFHGLSR--LTILYLFNNSLASLPGEALADLPALEFL 228
Query 437 DLGLN 441
L N
Sbjct 229 RLNAN 233
>7lhw_A A Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.9 bits (141), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 133/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H L+L NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTH-----LDLHSNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.4 bits (85), Expect = 0.98, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 35.0 bits (79), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>8fo9_F F Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.0 bits (84), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 34.7 bits (78), Expect = 7.4, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>8fo8_D E Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.0 bits (84), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 78/291 (27%), Positives = 126/291 (43%), Gaps = 44/291 (15%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSH-NGLSSTKLGTQVQLENLQE----------------- 175
I I + +K+ ++ L +H + LS L ++E+
Sbjct 1118 KISGICSPLRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTI 1177
Query 176 LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNVQL 233
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1178 LKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQIS 1233
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1234 ILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 34.3 bits (77), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>8fo8_C C Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.0 bits (84), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 78/291 (27%), Positives = 126/291 (43%), Gaps = 44/291 (15%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSH-NGLSSTKLGTQVQLENLQE----------------- 175
I I + +K+ ++ L +H + LS L ++E+
Sbjct 1118 KISGICSPLRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTI 1177
Query 176 LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNVQL 233
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1178 LKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQIS 1233
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1234 ILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 34.3 bits (77), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>5cmp_C C Leucine-rich repeat transmembrane protein FLRT3
Length=333
Score = 57.0 bits (136), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 82/311 (26%), Positives = 132/311 (42%), Gaps = 40/311 (13%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLP-AANFTRYSQLTSLD 81
S + C C+ LT +P +P + T L L +NQ+ ++ ++ +
Sbjct 6 SCPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIY 65
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIK 139
+ N++ + L + +K L+LQ N + ++ + + L ELHL NS+ I+
Sbjct 66 LYHNSLDEFPTNLPK---YVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 122
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
F L L LS N LS+ G +E EL L +N+I + S L +SL
Sbjct 123 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIE---ELRLDDNRISTISSPSLQGL--TSL 177
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
K+L L N LNN LG +K+ L N + LSL +
Sbjct 178 KRLVLDGN-------------------LLNNHGLG----DKVFFNLVN--LTELSLVRNS 212
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH 319
L+ + L TNL L L N++N V ++F++L QL + NN+ +L
Sbjct 213 LTAAP----VNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD 268
Query 320 GLFNVRYLNLK 330
L N+ L L+
Sbjct 269 DLDNITQLILR 279
Score = 51.2 bits (121), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 70/280 (25%), Positives = 120/280 (43%), Gaps = 44/280 (16%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L +N I I D+ S + +LE L L N + +I E + YL+L
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAV----------SIEEGAFRDSNYLRL 134
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
L L R L + P+ R + L L +N I+ I+ L+GL
Sbjct 135 -------------LFLSRNHLSTI-----PWGLPRTIEELRLDDNRISTISSPSLQGLTS 176
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L+ L L N L + G ++F L +L L+L N PV + L+ +
Sbjct 177 LKRLVLDGN----LLNNHGLGDKVFF--NLVNLTELSLVRNSLTAAPVNLPGT--NLRKL 228
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTC 651
L N++N +P + F+ L L++ N ++++ + +F N+T+L +R NP+ C C
Sbjct 229 YLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD-DLDNITQLILRNNPWYCGC 287
Query 652 ESIAWFVNWINE--THTNIPELSSHYLCNTPPHYHGFPVR 689
+ + W +W+ N+ L +C P G ++
Sbjct 288 K-MKWVRDWLQSLPVKVNVRGL----MCQAPEKVRGMAIK 322
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 31/210 (15%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L NN+ + DS + +P LE L+ N++ + G F R N R
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE--EGAF--RDSNYLRLLFLSRN 140
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS--------- 389
L+++P + + +E L ++DN I I S GL +LK L L +
Sbjct 141 HLSTIP------WGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGD 194
Query 390 --FTSLRTLTNETFV--SLAHSPLHI-------LNLTKNKISKIESDAFSWLGHLEVLDL 438
F +L LT + V SL +P+++ L L N I+++ +AFS+L L LD+
Sbjct 195 KVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 254
Query 439 GLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
N + G + L+NI ++ L N +
Sbjct 255 SNNNLSNLPQGI-FDDLDNITQLILRNNPW 283
Score = 43.5 bits (101), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 41/142 (29%), Positives = 68/142 (48%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ +P LP I L L N++ + + + + L L + N ++ L ++ L
Sbjct 142 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 201
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L+L N L+ TNL +L+L N I ++ N F + L LD+S+N L
Sbjct 202 NLTELSLVRNSLTAAPVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 259
Query 160 SSTKLGTQVQLENLQELLLSNN 181
S+ G L+N+ +L+L NN
Sbjct 260 SNLPQGIFDDLDNITQLILRNN 281
Score = 41.2 bits (95), Expect = 0.040, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 36/221 (16%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS-- 403
+D+F K ++ L++++N+I I + + + L+ L L ++ S ++ F
Sbjct 71 LDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSN 130
Query 404 -----------LAHSP------LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
L+ P + L L N+IS I S + L L+ L L N +
Sbjct 131 YLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNH 190
Query 447 LTGQE-WRGLENIFEIYLSYNKYLQLTRNSFALVP------SLQRLMLRRVALKNVDSSP 499
G + + L N+ E L L RNS P +L++L L+ + V P
Sbjct 191 GLGDKVFFNLVNLTE--------LSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRV--PP 240
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+ F LR L LD+SNNN++N+ + + L+ + L L++N
Sbjct 241 NAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 281
>7drb_B C Membrane-localized LRR receptor-like protein
Length=934
Score = 58.2 bits (139), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 117/476 (25%), Positives = 200/476 (42%), Gaps = 77/476 (16%)
Query 244 ELANTSIRNLS---LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQL 300
E+AN+S+ +LS L ++ S+++ ++L T+LT +DLS N L+ +D F L L
Sbjct 231 EIANSSLISLSVLHLCCNEFSSSAKYSWLFNFSTSLTSIDLSNNQLDGQIDDRFGNLMYL 290
Query 301 EYFFLEYN-NIQHLFSHSLHGLFNVRYLNLKRSFTKQSI------------SLASLPKID 347
E+ L N++ S L +RYL++ + T Q + +L L D
Sbjct 291 EHLNLANELNLKGGIPSSFGNLTRLRYLDMSNTRTYQWLPELFVRLSGSRKTLEVLGLND 350
Query 348 DFSFQWL------KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS-----------F 390
+ F L L+ L ++ N + G F + +L+YL LS++ F
Sbjct 351 NSMFGSLVDVTRFSALKRLYLQKNVLNGFFMERFGQVSSLEYLDLSDNQMRGPLPDLALF 410
Query 391 TSLRTL---TNETFVSLAH-----SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE 442
SLR L +N + S L IL+++ N++ + ++ L +LE D N
Sbjct 411 PSLRELHLGSNHFNGRIPQGIGKLSQLKILDVSSNRLEGLP-ESMGQLSNLESFDASYNV 469
Query 443 IGQELTGQEWRGLENIFEIYLSYNKYLQLTR--------------NSFALVPSLQRLMLR 488
+ +T L ++ ++ LS+N T S L PS + +
Sbjct 470 LKGTITESHLSNLSSLVDLDLSFNSLALKTSIDWLPPFQLQVINLPSCNLGPSFPKWLQS 529
Query 489 R-------VALKNV-DSSPSPFQPLR-NLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
+ ++L N+ D+ PS F L ++ IL+LSNN I+ D++E ++DL
Sbjct 530 QNNYTVLDISLANISDALPSWFSGLPPDIKILNLSNNQISGRVSDLIENAYDYMVIDLSS 589
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN + GP+ + +++ I L N F + K +DL N +
Sbjct 590 NNFS---------GPLPLVP--TNVQIFYLHKNQFFGSISSICKSTTGATSLDLSHNQFS 638
Query 600 TLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIA 655
+ N +L LNL N + + G + NL L MR N F S++
Sbjct 639 GELPDCWMNATNLAVLNLAYNNFSGKLPQSLG-SLTNLEALYMRQNSFSGMLPSLS 693
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 34/114 (30%), Positives = 52/114 (46%), Gaps = 3/114 (3%)
Query 49 LPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQH 108
+PTN+ + L NQ ++ + TSLD+ N S P+ L VLNL +
Sbjct 599 VPTNVQIFYLHKNQFFGSISSICKSTTGATSLDLSHNQFSGELPDCWMNATNLAVLNLAY 658
Query 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ-KNLITLDLSHNGLSS 161
N S ++ TNL L++ NS + P + Q ++L LDL N L+
Sbjct 659 NNFSGKLPQSLGSLTNLEALYMRQNSFSGML--PSLSQCQSLQILDLGGNKLTG 710
Score = 35.0 bits (79), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 104/427 (24%), Positives = 166/427 (39%), Gaps = 91/427 (21%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
+++ L+L+ NQ+R P + + L L +G N + P+ KL LK+L++ N
Sbjct 388 SSLEYLDLSDNQMRG-PLPDLALFPSLRELHLGSNHFNGRIPQGIGKLSQLKILDVSSNR 446
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQK-IKNNPFVKQKNLITLDLSHNGLS-STKLG--- 165
L L + + +NL N ++ I + +L+ LDLS N L+ T +
Sbjct 447 LEGLPE-SMGQLSNLESFDASYNVLKGTITESHLSNLSSLVDLDLSFNSLALKTSIDWLP 505
Query 166 -TQVQLENLQELLLSNNKIQALKSEE----LDI-FANSS-------------LKKLELSS 206
Q+Q+ NL L + + L+S+ LDI AN S +K L LS+
Sbjct 506 PFQLQVINLPSCNLGPSFPKWLQSQNNYTVLDISLANISDALPSWFSGLPPDIKILNLSN 565
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRN---LSLSNSQLSTT 263
NQI GR+ L N + + ++L++ + L +N Q+
Sbjct 566 NQIS----------GRVSDLIENAY-------DYMVIDLSSNNFSGPLPLVPTNVQIFYL 608
Query 264 SNTTFLG------LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
F G T T LDLS+N + D + L L YNN S
Sbjct 609 HKNQFFGSISSICKSTTGATSLDLSHNQFSGELPDCWMNATNLAVLNLAYNNFSGKLPQS 668
Query 318 LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG-IKSNMFT 376
L L N+ L + +Q+ LP S + L+ L++ N + G I + + T
Sbjct 669 LGSLTNLEAL-----YMRQNSFSGMLP-----SLSQCQSLQILDLGGNKLTGRIPAWIGT 718
Query 377 GLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVL 436
L+NL+ IL+L NK S L L++L
Sbjct 719 DLLNLR----------------------------ILSLRFNKFYGSISPIICQLQFLQIL 750
Query 437 DLGLNEI 443
DL N +
Sbjct 751 DLSANGL 757
>7drb_D D Membrane-localized LRR receptor-like protein
Length=934
Score = 58.2 bits (139), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 117/476 (25%), Positives = 200/476 (42%), Gaps = 77/476 (16%)
Query 244 ELANTSIRNLS---LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQL 300
E+AN+S+ +LS L ++ S+++ ++L T+LT +DLS N L+ +D F L L
Sbjct 231 EIANSSLISLSVLHLCCNEFSSSAKYSWLFNFSTSLTSIDLSNNQLDGQIDDRFGNLMYL 290
Query 301 EYFFLEYN-NIQHLFSHSLHGLFNVRYLNLKRSFTKQSI------------SLASLPKID 347
E+ L N++ S L +RYL++ + T Q + +L L D
Sbjct 291 EHLNLANELNLKGGIPSSFGNLTRLRYLDMSNTRTYQWLPELFVRLSGSRKTLEVLGLND 350
Query 348 DFSFQWL------KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS-----------F 390
+ F L L+ L ++ N + G F + +L+YL LS++ F
Sbjct 351 NSMFGSLVDVTRFSALKRLYLQKNVLNGFFMERFGQVSSLEYLDLSDNQMRGPLPDLALF 410
Query 391 TSLRTL---TNETFVSLAH-----SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE 442
SLR L +N + S L IL+++ N++ + ++ L +LE D N
Sbjct 411 PSLRELHLGSNHFNGRIPQGIGKLSQLKILDVSSNRLEGLP-ESMGQLSNLESFDASYNV 469
Query 443 IGQELTGQEWRGLENIFEIYLSYNKYLQLTR--------------NSFALVPSLQRLMLR 488
+ +T L ++ ++ LS+N T S L PS + +
Sbjct 470 LKGTITESHLSNLSSLVDLDLSFNSLALKTSIDWLPPFQLQVINLPSCNLGPSFPKWLQS 529
Query 489 R-------VALKNV-DSSPSPFQPLR-NLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
+ ++L N+ D+ PS F L ++ IL+LSNN I+ D++E ++DL
Sbjct 530 QNNYTVLDISLANISDALPSWFSGLPPDIKILNLSNNQISGRVSDLIENAYDYMVIDLSS 589
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN + GP+ + +++ I L N F + K +DL N +
Sbjct 590 NNFS---------GPLPLVP--TNVQIFYLHKNQFFGSISSICKSTTGATSLDLSHNQFS 638
Query 600 TLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIA 655
+ N +L LNL N + + G + NL L MR N F S++
Sbjct 639 GELPDCWMNATNLAVLNLAYNNFSGKLPQSLG-SLTNLEALYMRQNSFSGMLPSLS 693
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 34/114 (30%), Positives = 52/114 (46%), Gaps = 3/114 (3%)
Query 49 LPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQH 108
+PTN+ + L NQ ++ + TSLD+ N S P+ L VLNL +
Sbjct 599 VPTNVQIFYLHKNQFFGSISSICKSTTGATSLDLSHNQFSGELPDCWMNATNLAVLNLAY 658
Query 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ-KNLITLDLSHNGLSS 161
N S ++ TNL L++ NS + P + Q ++L LDL N L+
Sbjct 659 NNFSGKLPQSLGSLTNLEALYMRQNSFSGML--PSLSQCQSLQILDLGGNKLTG 710
Score = 35.0 bits (79), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 104/427 (24%), Positives = 166/427 (39%), Gaps = 91/427 (21%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
+++ L+L+ NQ+R P + + L L +G N + P+ KL LK+L++ N
Sbjct 388 SSLEYLDLSDNQMRG-PLPDLALFPSLRELHLGSNHFNGRIPQGIGKLSQLKILDVSSNR 446
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQK-IKNNPFVKQKNLITLDLSHNGLS-STKLG--- 165
L L + + +NL N ++ I + +L+ LDLS N L+ T +
Sbjct 447 LEGLPE-SMGQLSNLESFDASYNVLKGTITESHLSNLSSLVDLDLSFNSLALKTSIDWLP 505
Query 166 -TQVQLENLQELLLSNNKIQALKSEE----LDI-FANSS-------------LKKLELSS 206
Q+Q+ NL L + + L+S+ LDI AN S +K L LS+
Sbjct 506 PFQLQVINLPSCNLGPSFPKWLQSQNNYTVLDISLANISDALPSWFSGLPPDIKILNLSN 565
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRN---LSLSNSQLSTT 263
NQI GR+ L N + + ++L++ + L +N Q+
Sbjct 566 NQIS----------GRVSDLIENAY-------DYMVIDLSSNNFSGPLPLVPTNVQIFYL 608
Query 264 SNTTFLG------LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
F G T T LDLS+N + D + L L YNN S
Sbjct 609 HKNQFFGSISSICKSTTGATSLDLSHNQFSGELPDCWMNATNLAVLNLAYNNFSGKLPQS 668
Query 318 LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG-IKSNMFT 376
L L N+ L + +Q+ LP S + L+ L++ N + G I + + T
Sbjct 669 LGSLTNLEAL-----YMRQNSFSGMLP-----SLSQCQSLQILDLGGNKLTGRIPAWIGT 718
Query 377 GLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVL 436
L+NL+ IL+L NK S L L++L
Sbjct 719 DLLNLR----------------------------ILSLRFNKFYGSISPIICQLQFLQIL 750
Query 437 DLGLNEI 443
DL N +
Sbjct 751 DLSANGL 757
>1fyx_A A TOLL-LIKE RECEPTOR 2
Length=165
Score = 54.7 bits (130), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 38/146 (26%), Positives = 75/146 (51%), Gaps = 4/146 (3%)
Query 756 YAAYIIHAYKDKDWVWEHFSSMEKED--QSLKFCLEERDFEAGVFELEAIVNSIKRSRKI 813
Y A++ ++ +D WV E+ E E+ K L +RDF G + ++ I++SI++S K
Sbjct 6 YDAFVSYSERDAYWV-ENLMVQELENFNPPFKLXLHKRDFIHGKWIIDNIIDSIEKSHKT 64
Query 814 IFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDSIILVFLEEIPDYKLNHALCLRRGMFKS 873
+FV++ + +K K +++ + + ++N D+ IL+ LE I + R + +
Sbjct 65 VFVLSENFVKSEWXK-YELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFXKLRKIMNT 123
Query 874 HCILNWPVQKERIGAFRHKLQVALGS 899
L WP+ + + F L+ A+ S
Sbjct 124 KTYLEWPMDEAQREGFWVNLRAAIKS 149
>7drc_B C Membrane-localized LRR receptor-like protein
Length=934
Score = 58.2 bits (139), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 117/476 (25%), Positives = 200/476 (42%), Gaps = 77/476 (16%)
Query 244 ELANTSIRNLS---LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQL 300
E+AN+S+ +LS L ++ S+++ ++L T+LT +DLS N L+ +D F L L
Sbjct 231 EIANSSLISLSVLHLCCNEFSSSAKYSWLFNFSTSLTSIDLSNNQLDGQIDDRFGNLMYL 290
Query 301 EYFFLEYN-NIQHLFSHSLHGLFNVRYLNLKRSFTKQSI------------SLASLPKID 347
E+ L N++ S L +RYL++ + T Q + +L L D
Sbjct 291 EHLNLANELNLKGGIPSSFGNLTRLRYLDMSNTRTYQWLPELFVRLSGSRKTLEVLGLND 350
Query 348 DFSFQWL------KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS-----------F 390
+ F L L+ L ++ N + G F + +L+YL LS++ F
Sbjct 351 NSMFGSLVDVTRFSALKRLYLQKNVLNGFFMERFGQVSSLEYLDLSDNQMRGPLPDLALF 410
Query 391 TSLRTL---TNETFVSLAH-----SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE 442
SLR L +N + S L IL+++ N++ + ++ L +LE D N
Sbjct 411 PSLRELHLGSNHFNGRIPQGIGKLSQLKILDVSSNRLEGLP-ESMGQLSNLESFDASYNV 469
Query 443 IGQELTGQEWRGLENIFEIYLSYNKYLQLTR--------------NSFALVPSLQRLMLR 488
+ +T L ++ ++ LS+N T S L PS + +
Sbjct 470 LKGTITESHLSNLSSLVDLDLSFNSLALKTSIDWLPPFQLQVINLPSCNLGPSFPKWLQS 529
Query 489 R-------VALKNV-DSSPSPFQPLR-NLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
+ ++L N+ D+ PS F L ++ IL+LSNN I+ D++E ++DL
Sbjct 530 QNNYTVLDISLANISDALPSWFSGLPPDIKILNLSNNQISGRVSDLIENAYDYMVIDLSS 589
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN + GP+ + +++ I L N F + K +DL N +
Sbjct 590 NNFS---------GPLPLVP--TNVQIFYLHKNQFFGSISSICKSTTGATSLDLSHNQFS 638
Query 600 TLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIA 655
+ N +L LNL N + + G + NL L MR N F S++
Sbjct 639 GELPDCWMNATNLAVLNLAYNNFSGKLPQSLG-SLTNLEALYMRQNSFSGMLPSLS 693
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 135/551 (25%), Positives = 226/551 (41%), Gaps = 93/551 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
+++ L+L+ NQ+R P + + L L +G N + P+ KL LK+L++ N
Sbjct 388 SSLEYLDLSDNQMRG-PLPDLALFPSLRELHLGSNHFNGRIPQGIGKLSQLKILDVSSNR 446
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQK-IKNNPFVKQKNLITLDLSHNGLS-STKLG--- 165
L L + + +NL N ++ I + +L+ LDLS N L+ T +
Sbjct 447 LEGLPE-SMGQLSNLESFDASYNVLKGTITESHLSNLSSLVDLDLSFNSLALKTSIDWLP 505
Query 166 -TQVQLENLQELLLSNNKIQALKSEE----LDI-FANSS-------------LKKLELSS 206
Q+Q+ NL L + + L+S+ LDI AN S +K L LS+
Sbjct 506 PFQLQVINLPSCNLGPSFPKWLQSQNNYTVLDISLANISDALPSWFSGLPPDIKILNLSN 565
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRN---LSLSNSQLSTT 263
NQI GR+ L N + + ++L++ + L +N Q+
Sbjct 566 NQIS----------GRVSDLIENAY-------DYMVIDLSSNNFSGPLPLVPTNVQIFYL 608
Query 264 SNTTFLG------LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
F G T T LDLS+N + D + L L YNN S
Sbjct 609 HKNQFFGSISSICKSTTGATSLDLSHNQFSGELPDCWMNATNLAVLNLAYNNFSGKLPQS 668
Query 318 LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG-IKSNMFT 376
L L N+ L + +Q+ LP S + L+ L++ N + G I + + T
Sbjct 669 LGSLTNLEAL-----YMRQNSFSGMLP-----SLSQCQSLQILDLGGNKLTGRIPAWIGT 718
Query 377 GLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS-KIES--DAFSWLGHL 433
L+NL+ LSL F + L L IL+L+ N ++ KI + F+ L
Sbjct 719 DLLNLRILSLR--FNKFYGSISPIICQLQF--LQILDLSANGLAGKIPQCFNNFTLLHQE 774
Query 434 EVLDLGLNEIGQELTGQ-------------EWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
L + + Q G+ +W+ E ++ L+Y K + L+ N LV
Sbjct 775 NGLGEPMEFLVQGFYGKYPRHYSYLGNLLVQWKNQEAEYKNPLTYLKTIDLSSN--KLVG 832
Query 481 SLQRLMLRRVALKNVDSSPSPFQP--------LRNLTILDLSNNNIANINDDMLEGLEKL 532
+ + M LK+++ S + ++ L LDLS N ++ + L L +
Sbjct 833 GIPKEMAEMRGLKSLNLSRNDLNGSIIKGIGQMKMLESLDLSRNQLSGMIPKDLANLTFI 892
Query 533 EILDLQHNNLA 543
+LDL +N+L+
Sbjct 893 GVLDLSNNHLS 903
Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 137/553 (25%), Positives = 218/553 (39%), Gaps = 105/553 (19%)
Query 69 ANFTRYSQLTSLDVGFNTISKLEPELCQKLP----MLKVLNLQHNEL-SQLSDKTFAFCT 123
++F ++L LD+ + PEL +L L+VL L N + L D T +
Sbjct 307 SSFGNLTRLRYLDMSNTRTYQWLPELFVRLSGSRKTLEVLGLNDNSMFGSLVDVTRF--S 364
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
L L+L N + F + +L LDLS N + L +L+EL L +N
Sbjct 365 ALKRLYLQKNVLNGFFMERFGQVSSLEYLDLSDNQMRG-PLPDLALFPSLRELHLGSNHF 423
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
+ + S LK L++SSN+++ G ++G+L L +
Sbjct 424 NGRIPQGIGKL--SQLKILDVSSNRLE----GLPESMGQLSNLESFD------------- 464
Query 244 ELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLP--QLE 301
A+ ++ +++ S LS S+ L LDLS+N+L + S WLP QL+
Sbjct 465 --ASYNVLKGTITESHLSNLSS----------LVDLDLSFNSLAL--KTSIDWLPPFQLQ 510
Query 302 YFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCL---- 357
L N+ F ++L + ++T ISLA+ I D W L
Sbjct 511 VINLPSCNLGPSFP---------KWLQSQNNYTVLDISLAN---ISDALPSWFSGLPPDI 558
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETFVSLAHSPLHILNLTK 416
+ LN+ +N I G S++ + + LS N+F+ + L + + I L K
Sbjct 559 KILNLSNNQISGRVSDLIENAYDYMVIDLSSNNFSGP--------LPLVPTNVQIFYLHK 610
Query 417 NKI-SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNS 475
N+ I S S G LDL N+ EL W N+ + L+YN + S
Sbjct 611 NQFFGSISSICKSTTGATS-LDLSHNQFSGELP-DCWMNATNLAVLNLAYNNFSGKLPQS 668
Query 476 FALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEIL 535
+ +L+ L +R+ + + S S Q L+ ILDL N +
Sbjct 669 LGSLTNLEALYMRQNSFSGMLPSLSQCQSLQ---ILDLGGNKLT---------------- 709
Query 536 DLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGL 595
R+ P + L +L IL+L N F + L L+I+DL
Sbjct 710 -------GRI--------PAWIGTDLLNLRILSLRFNKFYGSISPIICQLQFLQILDLSA 754
Query 596 NNLNTLPASVFNN 608
N L FNN
Sbjct 755 NGLAGKIPQCFNN 767
Score = 42.4 bits (98), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 53/174 (30%), Positives = 78/174 (45%), Gaps = 10/174 (6%)
Query 49 LPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQH 108
+PTN+ + L NQ ++ + TSLD+ N S P+ L VLNL +
Sbjct 599 VPTNVQIFYLHKNQFFGSISSICKSTTGATSLDLSHNQFSGELPDCWMNATNLAVLNLAY 658
Query 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ-KNLITLDLSHNGLSS---TKL 164
N S ++ TNL L++ NS + P + Q ++L LDL N L+ +
Sbjct 659 NNFSGKLPQSLGSLTNLEALYMRQNSFSGML--PSLSQCQSLQILDLGGNKLTGRIPAWI 716
Query 165 GTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH 218
GT L NL+ L L NK S I L+ L+LS+N + P CF+
Sbjct 717 GT--DLLNLRILSLRFNKFYGSISPI--ICQLQFLQILDLSANGLAGKIPQCFN 766
>8hq2_B D Leucine-rich glioma-inactivated protein 1
Length=526
Score = 57.8 bits (138), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 40/135 (30%), Positives = 66/135 (49%), Gaps = 9/135 (7%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIF-KGLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Query 684 HGFPVRLFDTSSCKD 698
R ++ S KD
Sbjct 176 KK---RKINSLSSKD 187
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/91 (33%), Positives = 54/91 (59%), Gaps = 9/91 (10%)
Query 275 NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
+L +L + N+ +V+ +D+F LP LEY F+E NNI+ + H+ GL ++ +L+L +
Sbjct 61 SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN-- 118
Query 335 KQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
+L +LPK D F+ L L ++++ N
Sbjct 119 ----NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 38.1 bits (87), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (3%)
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N + ++ ++F +P L+ L + +K++ S F+ L++L L L+NNN+ + D+
Sbjct 70 NSFDVISDDAFIGLPHLEYLFIENNNIKSI--SRHTFRGLKSLIHLSLANNNLQTLPKDI 127
Query 526 LEGLEKLEILDLQHNNL 542
+GL+ L +DL+ N+
Sbjct 128 FKGLDSLTNVDLRGNSF 144
Score = 35.8 bits (81), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS 464
A L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+
Sbjct 58 ATPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLA 116
Query 465 YNKYLQLTRNSFALVPSLQRLMLR 488
N L ++ F + SL + LR
Sbjct 117 NNNLQTLPKDIFKGLDSLTNVDLR 140
Score = 35.4 bits (80), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
S I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F
Sbjct 71 SFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIF 128
Query 402 VSL 404
L
Sbjct 129 KGL 131
>8hq2_D E Leucine-rich glioma-inactivated protein 1
Length=526
Score = 57.8 bits (138), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 40/135 (30%), Positives = 66/135 (49%), Gaps = 9/135 (7%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIF-KGLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Query 684 HGFPVRLFDTSSCKD 698
R ++ S KD
Sbjct 176 KK---RKINSLSSKD 187
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 30/91 (33%), Positives = 54/91 (59%), Gaps = 9/91 (10%)
Query 275 NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
+L +L + N+ +V+ +D+F LP LEY F+E NNI+ + H+ GL ++ +L+L +
Sbjct 61 SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN-- 118
Query 335 KQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
+L +LPK D F+ L L ++++ N
Sbjct 119 ----NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 38.1 bits (87), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (3%)
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N + ++ ++F +P L+ L + +K++ S F+ L++L L L+NNN+ + D+
Sbjct 70 NSFDVISDDAFIGLPHLEYLFIENNNIKSI--SRHTFRGLKSLIHLSLANNNLQTLPKDI 127
Query 526 LEGLEKLEILDLQHNNL 542
+GL+ L +DL+ N+
Sbjct 128 FKGLDSLTNVDLRGNSF 144
Score = 35.8 bits (81), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 1/84 (1%)
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS 464
A L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+
Sbjct 58 ATPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLA 116
Query 465 YNKYLQLTRNSFALVPSLQRLMLR 488
N L ++ F + SL + LR
Sbjct 117 NNNLQTLPKDIFKGLDSLTNVDLR 140
Score = 35.4 bits (80), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
S I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F
Sbjct 71 SFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIF 128
Query 402 VSL 404
L
Sbjct 129 KGL 131
>8fo9_E E Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.0 bits (84), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 81/293 (28%), Positives = 127/293 (43%), Gaps = 48/293 (16%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTK---LGTQVQLENLQE--------------- 175
I I + ++ K L L+LS N +SS L ++E+
Sbjct 1118 KISGICSP--LRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSM 1175
Query 176 --LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNV 231
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1176 TILKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQ 1231
Query 232 QLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1232 ISILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 34.3 bits (77), Expect = 7.9, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>8fo2_B E Leucine-rich repeat serine/threonine-protein kinase
2
Length=2527
Score = 58.5 bits (140), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 84/308 (27%), Positives = 132/308 (43%), Gaps = 47/308 (15%)
Query 362 MEDNDIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS 420
+ D D K + L +L+ L L N+ TS ET SL H LH NK +
Sbjct 994 LRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLH-----SNKFT 1048
Query 421 KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
S + + LD+ N+IG + + + LSYN+ + N +V
Sbjct 1049 SFPSYLLK-MSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVE 1107
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
L++L+L + + SP + L+ L IL+LS N+I++++++ LE K+E + N
Sbjct 1108 KLEQLILEGNKISGI---CSPLR-LKELKILNLSKNHISSLSENFLEACPKVESFSARMN 1163
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNT 600
LA A P P + IL L N F IP E +L L+ +D+ N++
Sbjct 1164 FLA-----AMPFLP-------PSMTILKLSQNKFSCIP-EAILNLPHLRSLDMSSNDIQY 1210
Query 601 LPASVF------------NNQVSLKSLNLQKNLITSVEK--------KVFGP---AFRNL 637
LP +NQ+S+ L+ + L + VEK K P NL
Sbjct 1211 LPGPAHWKSLNLRELLFSHNQISILDLSEKAYLWSRVEKLHLSHNKLKEIPPEIGCLENL 1270
Query 638 TELDMRFN 645
T LD+ +N
Sbjct 1271 TSLDVSYN 1278
Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 78/291 (27%), Positives = 126/291 (43%), Gaps = 44/291 (15%)
Query 25 TTKCTVSHEVADCSHLKL-----TQVPDDLP---TNITVLNLTHNQLRRLPAANFTRYSQ 76
+ KC +S + L+L T P L ++T L+L N+ P+ + S
Sbjct 1001 SQKCCISVHLEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSY-LLKMSC 1059
Query 77 LTSLDVGFNTISK---LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ +LDV N I L+P + K P LK NL +N+LS + + L +L L N
Sbjct 1060 IANLDVSRNDIGPSVVLDPTV--KCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGN 1117
Query 134 SIQKIKNNPFVKQKNLITLDLSH-NGLSSTKLGTQVQLENLQE----------------- 175
I I + +K+ ++ L +H + LS L ++E+
Sbjct 1118 KISGICSPLRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTI 1177
Query 176 LLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH--AIGRLFGLFLNNVQL 233
L LS NK + L++ L+ L++SSN I ++ PG H ++ LF +N
Sbjct 1178 LKLSQNKFSCIPEAILNL---PHLRSLDMSSNDI-QYLPGPAHWKSLNLRELLFSHNQIS 1233
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYN 284
L+EK L + + L LS+++L +G NLT LD+SYN
Sbjct 1234 ILDLSEKAYLW---SRVEKLHLSHNKLKEIPPE--IGC-LENLTSLDVSYN 1278
Score = 34.3 bits (77), Expect = 9.0, Method: Compositional matrix adjust.
Identities = 79/333 (24%), Positives = 131/333 (39%), Gaps = 78/333 (23%)
Query 149 LITLDLSHNGLS-----STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLE 203
+ +LDLS N L S K V LE+L++L L N + + + + SL L+
Sbjct 984 ITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL--KSLTHLD 1041
Query 204 LSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT 263
L SN+ F P + + L ++ +GPS+ L T
Sbjct 1042 LHSNKFTSF-PSYLLKMSCIANLDVSRNDIGPSVV---------------------LDPT 1079
Query 264 SNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFN 323
+K L +LSYN L+ V + + +LE LE N I + S L
Sbjct 1080 -------VKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICSPL--RLKE 1130
Query 324 VRYLNLKRSFTKQSIS---LASLPKIDDFSFQW--------------------------- 353
++ LNL ++ S+S L + PK++ FS +
Sbjct 1131 LKILNLSKNHI-SSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFSCIP 1189
Query 354 -----LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP 408
L L L+M NDI + +NL+ L S++ S+ L+ + ++ S
Sbjct 1190 EAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAYL---WSR 1246
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
+ L+L+ NK+ +I + L +L LD+ N
Sbjct 1247 VEKLHLSHNKLKEIPPE-IGCLENLTSLDVSYN 1278
>6jbu_B B Leucine-rich repeat transmembrane protein FLRT3
Length=347
Score = 57.0 bits (136), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 82/311 (26%), Positives = 132/311 (42%), Gaps = 40/311 (13%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLP-AANFTRYSQLTSLD 81
S + C C+ LT +P +P + T L L +NQ+ ++ ++ +
Sbjct 9 SCPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIY 68
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIK 139
+ N++ + L + +K L+LQ N + ++ + + L ELHL NS+ I+
Sbjct 69 LYHNSLDEFPTNLPK---YVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 125
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
F L L LS N LS+ G +E EL L +N+I + S L +SL
Sbjct 126 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIE---ELRLDDNRISTISSPSLQGL--TSL 180
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
K+L L N LNN LG +K+ L N + LSL +
Sbjct 181 KRLVLDGN-------------------LLNNHGLG----DKVFFNLVN--LTELSLVRNS 215
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH 319
L+ + L TNL L L N++N V ++F++L QL + NN+ +L
Sbjct 216 LTAAP----VNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD 271
Query 320 GLFNVRYLNLK 330
L N+ L L+
Sbjct 272 DLDNITQLILR 282
Score = 51.2 bits (121), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 70/280 (25%), Positives = 120/280 (43%), Gaps = 44/280 (16%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L +N I I D+ S + +LE L L N + +I E + YL+L
Sbjct 88 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAV----------SIEEGAFRDSNYLRL 137
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
L L R L + P+ R + L L +N I+ I+ L+GL
Sbjct 138 -------------LFLSRNHLSTI-----PWGLPRTIEELRLDDNRISTISSPSLQGLTS 179
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L+ L L N L + G ++F L +L L+L N PV + L+ +
Sbjct 180 LKRLVLDGN----LLNNHGLGDKVFF--NLVNLTELSLVRNSLTAAPVNLPGT--NLRKL 231
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTC 651
L N++N +P + F+ L L++ N ++++ + +F N+T+L +R NP+ C C
Sbjct 232 YLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD-DLDNITQLILRNNPWYCGC 290
Query 652 ESIAWFVNWINE--THTNIPELSSHYLCNTPPHYHGFPVR 689
+ + W +W+ N+ L +C P G ++
Sbjct 291 K-MKWVRDWLQSLPVKVNVRGL----MCQAPEKVRGMAIK 325
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 31/210 (15%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L NN+ + DS + +P LE L+ N++ + G F R N R
Sbjct 88 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE--EGAF--RDSNYLRLLFLSRN 143
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS--------- 389
L+++P + + +E L ++DN I I S GL +LK L L +
Sbjct 144 HLSTIP------WGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGD 197
Query 390 --FTSLRTLTNETFV--SLAHSPLHI-------LNLTKNKISKIESDAFSWLGHLEVLDL 438
F +L LT + V SL +P+++ L L N I+++ +AFS+L L LD+
Sbjct 198 KVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 257
Query 439 GLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
N + G + L+NI ++ L N +
Sbjct 258 SNNNLSNLPQGI-FDDLDNITQLILRNNPW 286
Score = 43.5 bits (101), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 41/142 (29%), Positives = 68/142 (48%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ +P LP I L L N++ + + + + L L + N ++ L ++ L
Sbjct 145 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 204
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L+L N L+ TNL +L+L N I ++ N F + L LD+S+N L
Sbjct 205 NLTELSLVRNSLTAAPVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 262
Query 160 SSTKLGTQVQLENLQELLLSNN 181
S+ G L+N+ +L+L NN
Sbjct 263 SNLPQGIFDDLDNITQLILRNN 284
Score = 41.2 bits (95), Expect = 0.041, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 36/221 (16%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS-- 403
+D+F K ++ L++++N+I I + + + L+ L L ++ S ++ F
Sbjct 74 LDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSN 133
Query 404 -----------LAHSP------LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
L+ P + L L N+IS I S + L L+ L L N +
Sbjct 134 YLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNH 193
Query 447 LTGQE-WRGLENIFEIYLSYNKYLQLTRNSFALVP------SLQRLMLRRVALKNVDSSP 499
G + + L N+ E L L RNS P +L++L L+ + V P
Sbjct 194 GLGDKVFFNLVNLTE--------LSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRV--PP 243
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+ F LR L LD+SNNN++N+ + + L+ + L L++N
Sbjct 244 NAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 284
>8y6b_B D Leucine-rich glioma-inactivated protein 1
Length=526
Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 40/135 (30%), Positives = 66/135 (49%), Gaps = 9/135 (7%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIF-KGLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Query 684 HGFPVRLFDTSSCKD 698
R ++ S KD
Sbjct 176 KK---RKINSLSSKD 187
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 36/114 (32%), Positives = 63/114 (55%), Gaps = 11/114 (10%)
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
+LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NNI+
Sbjct 40 SLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIK 97
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
+ H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 98 SISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 56/120 (47%), Gaps = 10/120 (8%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
P + L R + F P +L +L ++N+ I+DD GL LE L +++
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIEN 93
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN+ + +H +GL L L+L +N +P ++FK L L +DL N+ N
Sbjct 94 NNIKSISRHT--------FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 145
Score = 42.4 bits (98), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query 468 YLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLE 527
+ +++ SF PSLQ L+ + + S F L +L L + NNNI +I+
Sbjct 48 FTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENNNIKSISRHTFR 105
Query 528 GLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 106 GLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNSFN 145
Score = 38.1 bits (87), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (3%)
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N + ++ ++F +P L+ L + +K++ S F+ L++L L L+NNN+ + D+
Sbjct 70 NSFDVISDDAFIGLPHLEYLFIENNNIKSI--SRHTFRGLKSLIHLSLANNNLQTLPKDI 127
Query 526 LEGLEKLEILDLQHNNL 542
+GL+ L +DL+ N+
Sbjct 128 FKGLDSLTNVDLRGNSF 144
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 26/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLR 488
L ++ F + SL + LR
Sbjct 121 QTLPKDIFKGLDSLTNVDLR 140
Score = 35.4 bits (80), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
S I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F
Sbjct 71 SFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIF 128
Query 402 VSL 404
L
Sbjct 129 KGL 131
Score = 35.0 bits (79), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 48/208 (23%), Positives = 90/208 (43%), Gaps = 26/208 (13%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGLK-SLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNSF 144
Query 444 GQELTGQ---EWRGLEN--IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS 498
+ + EW G N + +IY P ++ + ++ K+ D
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIYCE-------------GPPEYKKRKINSLSSKDFDCI 191
Query 499 PSPFQPLRNLTILDLSNNNIANINDDML 526
+ F ++L LS + + +ND+ +
Sbjct 192 ITEFAKSQDLPYQSLSIDTFSYLNDEYV 219
>8y6b_F E Leucine-rich glioma-inactivated protein 1
Length=526
Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 40/135 (30%), Positives = 66/135 (49%), Gaps = 9/135 (7%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIF-KGLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Query 684 HGFPVRLFDTSSCKD 698
R ++ S KD
Sbjct 176 KK---RKINSLSSKD 187
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 36/114 (32%), Positives = 63/114 (55%), Gaps = 11/114 (10%)
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
+LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NNI+
Sbjct 40 SLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIK 97
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
+ H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 98 SISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 56/120 (47%), Gaps = 10/120 (8%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
P + L R + F P +L +L ++N+ I+DD GL LE L +++
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIEN 93
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN+ + +H +GL L L+L +N +P ++FK L L +DL N+ N
Sbjct 94 NNIKSISRHT--------FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 145
Score = 42.4 bits (98), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query 468 YLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLE 527
+ +++ SF PSLQ L+ + + S F L +L L + NNNI +I+
Sbjct 48 FTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENNNIKSISRHTFR 105
Query 528 GLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 106 GLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNSFN 145
Score = 38.1 bits (87), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (3%)
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N + ++ ++F +P L+ L + +K++ S F+ L++L L L+NNN+ + D+
Sbjct 70 NSFDVISDDAFIGLPHLEYLFIENNNIKSI--SRHTFRGLKSLIHLSLANNNLQTLPKDI 127
Query 526 LEGLEKLEILDLQHNNL 542
+GL+ L +DL+ N+
Sbjct 128 FKGLDSLTNVDLRGNSF 144
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 26/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLR 488
L ++ F + SL + LR
Sbjct 121 QTLPKDIFKGLDSLTNVDLR 140
Score = 35.4 bits (80), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
S I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F
Sbjct 71 SFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIF 128
Query 402 VSL 404
L
Sbjct 129 KGL 131
Score = 35.0 bits (79), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 48/208 (23%), Positives = 90/208 (43%), Gaps = 26/208 (13%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGLK-SLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNSF 144
Query 444 GQELTGQ---EWRGLEN--IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS 498
+ + EW G N + +IY P ++ + ++ K+ D
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIYCE-------------GPPEYKKRKINSLSSKDFDCI 191
Query 499 PSPFQPLRNLTILDLSNNNIANINDDML 526
+ F ++L LS + + +ND+ +
Sbjct 192 ITEFAKSQDLPYQSLSIDTFSYLNDEYV 219
>8y6b_E F Leucine-rich glioma-inactivated protein 1
Length=526
Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 40/135 (30%), Positives = 66/135 (49%), Gaps = 9/135 (7%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIF-KGLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Query 684 HGFPVRLFDTSSCKD 698
R ++ S KD
Sbjct 176 KK---RKINSLSSKD 187
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 36/114 (32%), Positives = 63/114 (55%), Gaps = 11/114 (10%)
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
+LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NNI+
Sbjct 40 SLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIK 97
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
+ H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 98 SISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 56/120 (47%), Gaps = 10/120 (8%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
P + L R + F P +L +L ++N+ I+DD GL LE L +++
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIEN 93
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN+ + +H +GL L L+L +N +P ++FK L L +DL N+ N
Sbjct 94 NNIKSISRHT--------FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 145
Score = 42.4 bits (98), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query 468 YLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLE 527
+ +++ SF PSLQ L+ + + S F L +L L + NNNI +I+
Sbjct 48 FTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENNNIKSISRHTFR 105
Query 528 GLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 106 GLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNSFN 145
Score = 38.1 bits (87), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (3%)
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N + ++ ++F +P L+ L + +K++ S F+ L++L L L+NNN+ + D+
Sbjct 70 NSFDVISDDAFIGLPHLEYLFIENNNIKSI--SRHTFRGLKSLIHLSLANNNLQTLPKDI 127
Query 526 LEGLEKLEILDLQHNNL 542
+GL+ L +DL+ N+
Sbjct 128 FKGLDSLTNVDLRGNSF 144
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 26/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLR 488
L ++ F + SL + LR
Sbjct 121 QTLPKDIFKGLDSLTNVDLR 140
Score = 35.4 bits (80), Expect = 3.6, Method: Compositional matrix adjust.
Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
S I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F
Sbjct 71 SFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIF 128
Query 402 VSL 404
L
Sbjct 129 KGL 131
Score = 35.0 bits (79), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 48/208 (23%), Positives = 90/208 (43%), Gaps = 26/208 (13%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGLK-SLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNSF 144
Query 444 GQELTGQ---EWRGLEN--IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS 498
+ + EW G N + +IY P ++ + ++ K+ D
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIYCE-------------GPPEYKKRKINSLSSKDFDCI 191
Query 499 PSPFQPLRNLTILDLSNNNIANINDDML 526
+ F ++L LS + + +ND+ +
Sbjct 192 ITEFAKSQDLPYQSLSIDTFSYLNDEYV 219
>8hq1_E E Leucine-rich glioma-inactivated protein 1
Length=526
Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIF-KGLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Score = 47.0 bits (110), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 36/114 (32%), Positives = 63/114 (55%), Gaps = 11/114 (10%)
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
+LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NNI+
Sbjct 40 SLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIK 97
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
+ H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 98 SISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 56/120 (47%), Gaps = 10/120 (8%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
P + L R + F P +L +L ++N+ I+DD GL LE L +++
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIEN 93
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN+ + +H +GL L L+L +N +P ++FK L L +DL N+ N
Sbjct 94 NNIKSISRHT--------FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 145
Score = 42.4 bits (98), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query 468 YLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLE 527
+ +++ SF PSLQ L+ + + S F L +L L + NNNI +I+
Sbjct 48 FTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENNNIKSISRHTFR 105
Query 528 GLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 106 GLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNSFN 145
Score = 38.1 bits (87), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (3%)
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N + ++ ++F +P L+ L + +K++ S F+ L++L L L+NNN+ + D+
Sbjct 70 NSFDVISDDAFIGLPHLEYLFIENNNIKSI--SRHTFRGLKSLIHLSLANNNLQTLPKDI 127
Query 526 LEGLEKLEILDLQHNNL 542
+GL+ L +DL+ N+
Sbjct 128 FKGLDSLTNVDLRGNSF 144
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 26/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLR 488
L ++ F + SL + LR
Sbjct 121 QTLPKDIFKGLDSLTNVDLR 140
Score = 35.0 bits (79), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
S I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F
Sbjct 71 SFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIF 128
Query 402 VSL 404
L
Sbjct 129 KGL 131
Score = 35.0 bits (79), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 48/208 (23%), Positives = 90/208 (43%), Gaps = 26/208 (13%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGLK-SLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNSF 144
Query 444 GQELTGQ---EWRGLEN--IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS 498
+ + EW G N + +IY P ++ + ++ K+ D
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIYCE-------------GPPEYKKRKINSLSSKDFDCI 191
Query 499 PSPFQPLRNLTILDLSNNNIANINDDML 526
+ F ++L LS + + +ND+ +
Sbjct 192 ITEFAKSQDLPYQSLSIDTFSYLNDEYV 219
>8hpy_D E Leucine-rich glioma-inactivated protein 1
Length=526
Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIF-KGLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Score = 47.0 bits (110), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 36/114 (32%), Positives = 63/114 (55%), Gaps = 11/114 (10%)
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
+LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NNI+
Sbjct 40 SLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIK 97
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
+ H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 98 SISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 56/120 (47%), Gaps = 10/120 (8%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
P + L R + F P +L +L ++N+ I+DD GL LE L +++
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIEN 93
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN+ + +H +GL L L+L +N +P ++FK L L +DL N+ N
Sbjct 94 NNIKSISRHT--------FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 145
Score = 42.4 bits (98), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query 468 YLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLE 527
+ +++ SF PSLQ L+ + + S F L +L L + NNNI +I+
Sbjct 48 FTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENNNIKSISRHTFR 105
Query 528 GLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 106 GLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNSFN 145
Score = 38.1 bits (87), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (3%)
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N + ++ ++F +P L+ L + +K++ S F+ L++L L L+NNN+ + D+
Sbjct 70 NSFDVISDDAFIGLPHLEYLFIENNNIKSI--SRHTFRGLKSLIHLSLANNNLQTLPKDI 127
Query 526 LEGLEKLEILDLQHNNL 542
+GL+ L +DL+ N+
Sbjct 128 FKGLDSLTNVDLRGNSF 144
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 26/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLR 488
L ++ F + SL + LR
Sbjct 121 QTLPKDIFKGLDSLTNVDLR 140
Score = 35.0 bits (79), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
S I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F
Sbjct 71 SFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIF 128
Query 402 VSL 404
L
Sbjct 129 KGL 131
Score = 35.0 bits (79), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 48/208 (23%), Positives = 90/208 (43%), Gaps = 26/208 (13%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGLK-SLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNSF 144
Query 444 GQELTGQ---EWRGLEN--IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS 498
+ + EW G N + +IY P ++ + ++ K+ D
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIYCE-------------GPPEYKKRKINSLSSKDFDCI 191
Query 499 PSPFQPLRNLTILDLSNNNIANINDDML 526
+ F ++L LS + + +ND+ +
Sbjct 192 ITEFAKSQDLPYQSLSIDTFSYLNDEYV 219
>8hq1_F F Leucine-rich glioma-inactivated protein 1
Length=526
Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIF-KGLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Score = 47.0 bits (110), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 36/114 (32%), Positives = 63/114 (55%), Gaps = 11/114 (10%)
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
+LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NNI+
Sbjct 40 SLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIK 97
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
+ H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 98 SISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 56/120 (47%), Gaps = 10/120 (8%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
P + L R + F P +L +L ++N+ I+DD GL LE L +++
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIEN 93
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN+ + +H +GL L L+L +N +P ++FK L L +DL N+ N
Sbjct 94 NNIKSISRHT--------FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 145
Score = 42.4 bits (98), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query 468 YLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLE 527
+ +++ SF PSLQ L+ + + S F L +L L + NNNI +I+
Sbjct 48 FTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENNNIKSISRHTFR 105
Query 528 GLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 106 GLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNSFN 145
Score = 38.1 bits (87), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (3%)
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N + ++ ++F +P L+ L + +K++ S F+ L++L L L+NNN+ + D+
Sbjct 70 NSFDVISDDAFIGLPHLEYLFIENNNIKSI--SRHTFRGLKSLIHLSLANNNLQTLPKDI 127
Query 526 LEGLEKLEILDLQHNNL 542
+GL+ L +DL+ N+
Sbjct 128 FKGLDSLTNVDLRGNSF 144
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 26/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLR 488
L ++ F + SL + LR
Sbjct 121 QTLPKDIFKGLDSLTNVDLR 140
Score = 35.0 bits (79), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
S I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F
Sbjct 71 SFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIF 128
Query 402 VSL 404
L
Sbjct 129 KGL 131
Score = 35.0 bits (79), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 48/208 (23%), Positives = 90/208 (43%), Gaps = 26/208 (13%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGLK-SLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNSF 144
Query 444 GQELTGQ---EWRGLEN--IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS 498
+ + EW G N + +IY P ++ + ++ K+ D
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIYCE-------------GPPEYKKRKINSLSSKDFDCI 191
Query 499 PSPFQPLRNLTILDLSNNNIANINDDML 526
+ F ++L LS + + +ND+ +
Sbjct 192 ITEFAKSQDLPYQSLSIDTFSYLNDEYV 219
>8hq1_D D Leucine-rich glioma-inactivated protein 1
Length=526
Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIF-KGLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Score = 47.0 bits (110), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 36/114 (32%), Positives = 63/114 (55%), Gaps = 11/114 (10%)
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
+LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NNI+
Sbjct 40 SLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIK 97
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
+ H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 98 SISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 56/120 (47%), Gaps = 10/120 (8%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
P + L R + F P +L +L ++N+ I+DD GL LE L +++
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIEN 93
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN+ + +H +GL L L+L +N +P ++FK L L +DL N+ N
Sbjct 94 NNIKSISRHT--------FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 145
Score = 42.4 bits (98), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query 468 YLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLE 527
+ +++ SF PSLQ L+ + + S F L +L L + NNNI +I+
Sbjct 48 FTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENNNIKSISRHTFR 105
Query 528 GLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 106 GLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNSFN 145
Score = 38.1 bits (87), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (3%)
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N + ++ ++F +P L+ L + +K++ S F+ L++L L L+NNN+ + D+
Sbjct 70 NSFDVISDDAFIGLPHLEYLFIENNNIKSI--SRHTFRGLKSLIHLSLANNNLQTLPKDI 127
Query 526 LEGLEKLEILDLQHNNL 542
+GL+ L +DL+ N+
Sbjct 128 FKGLDSLTNVDLRGNSF 144
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 26/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLR 488
L ++ F + SL + LR
Sbjct 121 QTLPKDIFKGLDSLTNVDLR 140
Score = 35.0 bits (79), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
S I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F
Sbjct 71 SFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIF 128
Query 402 VSL 404
L
Sbjct 129 KGL 131
Score = 35.0 bits (79), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 48/208 (23%), Positives = 90/208 (43%), Gaps = 26/208 (13%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGLK-SLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNSF 144
Query 444 GQELTGQ---EWRGLEN--IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS 498
+ + EW G N + +IY P ++ + ++ K+ D
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIYCE-------------GPPEYKKRKINSLSSKDFDCI 191
Query 499 PSPFQPLRNLTILDLSNNNIANINDDML 526
+ F ++L LS + + +ND+ +
Sbjct 192 ITEFAKSQDLPYQSLSIDTFSYLNDEYV 219
>8hpy_B D Leucine-rich glioma-inactivated protein 1
Length=526
Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 121
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 122 TLPKDIF-KGLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 175
Score = 47.0 bits (110), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 36/114 (32%), Positives = 63/114 (55%), Gaps = 11/114 (10%)
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
+LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NNI+
Sbjct 40 SLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIK 97
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
+ H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 98 SISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 142
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 56/120 (47%), Gaps = 10/120 (8%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
P + L R + F P +L +L ++N+ I+DD GL LE L +++
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIEN 93
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN+ + +H +GL L L+L +N +P ++FK L L +DL N+ N
Sbjct 94 NNIKSISRHT--------FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 145
Score = 42.4 bits (98), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query 468 YLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLE 527
+ +++ SF PSLQ L+ + + S F L +L L + NNNI +I+
Sbjct 48 FTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENNNIKSISRHTFR 105
Query 528 GLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 106 GLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNSFN 145
Score = 38.1 bits (87), Expect = 0.45, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (3%)
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N + ++ ++F +P L+ L + +K++ S F+ L++L L L+NNN+ + D+
Sbjct 70 NSFDVISDDAFIGLPHLEYLFIENNNIKSI--SRHTFRGLKSLIHLSLANNNLQTLPKDI 127
Query 526 LEGLEKLEILDLQHNNL 542
+GL+ L +DL+ N+
Sbjct 128 FKGLDSLTNVDLRGNSF 144
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 36 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 95
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 96 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 142
Score = 35.4 bits (80), Expect = 3.5, Method: Compositional matrix adjust.
Identities = 26/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 62 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 120
Query 469 LQLTRNSFALVPSLQRLMLR 488
L ++ F + SL + LR
Sbjct 121 QTLPKDIFKGLDSLTNVDLR 140
Score = 35.0 bits (79), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
S I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F
Sbjct 71 SFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIF 128
Query 402 VSL 404
L
Sbjct 129 KGL 131
Score = 35.0 bits (79), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 48/208 (23%), Positives = 90/208 (43%), Gaps = 26/208 (13%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 29 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 88
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 89 LFIENN--NIKSISRHTFRGLK-SLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNSF 144
Query 444 GQELTGQ---EWRGLEN--IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS 498
+ + EW G N + +IY P ++ + ++ K+ D
Sbjct 145 NCDCKLKWLVEWLGHTNATVEDIYCE-------------GPPEYKKRKINSLSSKDFDCI 191
Query 499 PSPFQPLRNLTILDLSNNNIANINDDML 526
+ F ++L LS + + +ND+ +
Sbjct 192 ITEFAKSQDLPYQSLSIDTFSYLNDEYV 219
>5cmn_D D Leucine-rich repeat transmembrane protein FLRT3
Length=333
Score = 57.0 bits (136), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 82/311 (26%), Positives = 132/311 (42%), Gaps = 40/311 (13%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLP-AANFTRYSQLTSLD 81
S + C C+ LT +P +P + T L L +NQ+ ++ ++ +
Sbjct 6 SCPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIY 65
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIK 139
+ N++ + L + +K L+LQ N + ++ + + L ELHL NS+ I+
Sbjct 66 LYHNSLDEFPTNLPK---YVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 122
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
F L L LS N LS+ G +E EL L +N+I + S L +SL
Sbjct 123 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIE---ELRLDDNRISTISSPSLQGL--TSL 177
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
K+L L N LNN LG +K+ L N + LSL +
Sbjct 178 KRLVLDGN-------------------LLNNHGLG----DKVFFNLVN--LTELSLVRNS 212
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH 319
L+ + L TNL L L N++N V ++F++L QL + NN+ +L
Sbjct 213 LTAAP----VNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD 268
Query 320 GLFNVRYLNLK 330
L N+ L L+
Sbjct 269 DLDNITQLILR 279
Score = 51.2 bits (121), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 70/280 (25%), Positives = 120/280 (43%), Gaps = 44/280 (16%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L +N I I D+ S + +LE L L N + +I E + YL+L
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAV----------SIEEGAFRDSNYLRL 134
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
L L R L + P+ R + L L +N I+ I+ L+GL
Sbjct 135 -------------LFLSRNHLSTI-----PWGLPRTIEELRLDDNRISTISSPSLQGLTS 176
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L+ L L N L + G ++F L +L L+L N PV + L+ +
Sbjct 177 LKRLVLDGN----LLNNHGLGDKVFF--NLVNLTELSLVRNSLTAAPVNLPGT--NLRKL 228
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTC 651
L N++N +P + F+ L L++ N ++++ + +F N+T+L +R NP+ C C
Sbjct 229 YLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD-DLDNITQLILRNNPWYCGC 287
Query 652 ESIAWFVNWINE--THTNIPELSSHYLCNTPPHYHGFPVR 689
+ + W +W+ N+ L +C P G ++
Sbjct 288 K-MKWVRDWLQSLPVKVNVRGL----MCQAPEKVRGMAIK 322
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 31/210 (15%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L NN+ + DS + +P LE L+ N++ + G F R N R
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE--EGAF--RDSNYLRLLFLSRN 140
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS--------- 389
L+++P + + +E L ++DN I I S GL +LK L L +
Sbjct 141 HLSTIP------WGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGD 194
Query 390 --FTSLRTLTNETFV--SLAHSPLHI-------LNLTKNKISKIESDAFSWLGHLEVLDL 438
F +L LT + V SL +P+++ L L N I+++ +AFS+L L LD+
Sbjct 195 KVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 254
Query 439 GLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
N + G + L+NI ++ L N +
Sbjct 255 SNNNLSNLPQGI-FDDLDNITQLILRNNPW 283
Score = 43.1 bits (100), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 41/142 (29%), Positives = 68/142 (48%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ +P LP I L L N++ + + + + L L + N ++ L ++ L
Sbjct 142 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 201
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L+L N L+ TNL +L+L N I ++ N F + L LD+S+N L
Sbjct 202 NLTELSLVRNSLTAAPVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 259
Query 160 SSTKLGTQVQLENLQELLLSNN 181
S+ G L+N+ +L+L NN
Sbjct 260 SNLPQGIFDDLDNITQLILRNN 281
Score = 40.8 bits (94), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 36/221 (16%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS-- 403
+D+F K ++ L++++N+I I + + + L+ L L ++ S ++ F
Sbjct 71 LDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSN 130
Query 404 -----------LAHSP------LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
L+ P + L L N+IS I S + L L+ L L N +
Sbjct 131 YLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNH 190
Query 447 LTGQE-WRGLENIFEIYLSYNKYLQLTRNSFALVP------SLQRLMLRRVALKNVDSSP 499
G + + L N+ E L L RNS P +L++L L+ + V P
Sbjct 191 GLGDKVFFNLVNLTE--------LSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRV--PP 240
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+ F LR L LD+SNNN++N+ + + L+ + L L++N
Sbjct 241 NAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 281
>5cmn_C C Leucine-rich repeat transmembrane protein FLRT3
Length=333
Score = 57.0 bits (136), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 82/311 (26%), Positives = 132/311 (42%), Gaps = 40/311 (13%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLP-AANFTRYSQLTSLD 81
S + C C+ LT +P +P + T L L +NQ+ ++ ++ +
Sbjct 6 SCPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIY 65
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIK 139
+ N++ + L + +K L+LQ N + ++ + + L ELHL NS+ I+
Sbjct 66 LYHNSLDEFPTNLPK---YVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 122
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
F L L LS N LS+ G +E EL L +N+I + S L +SL
Sbjct 123 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIE---ELRLDDNRISTISSPSLQGL--TSL 177
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
K+L L N LNN LG +K+ L N + LSL +
Sbjct 178 KRLVLDGN-------------------LLNNHGLG----DKVFFNLVN--LTELSLVRNS 212
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH 319
L+ + L TNL L L N++N V ++F++L QL + NN+ +L
Sbjct 213 LTAAP----VNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD 268
Query 320 GLFNVRYLNLK 330
L N+ L L+
Sbjct 269 DLDNITQLILR 279
Score = 51.2 bits (121), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 70/280 (25%), Positives = 120/280 (43%), Gaps = 44/280 (16%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L +N I I D+ S + +LE L L N + +I E + YL+L
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAV----------SIEEGAFRDSNYLRL 134
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
L L R L + P+ R + L L +N I+ I+ L+GL
Sbjct 135 -------------LFLSRNHLSTI-----PWGLPRTIEELRLDDNRISTISSPSLQGLTS 176
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L+ L L N L + G ++F L +L L+L N PV + L+ +
Sbjct 177 LKRLVLDGN----LLNNHGLGDKVFF--NLVNLTELSLVRNSLTAAPVNLPGT--NLRKL 228
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTC 651
L N++N +P + F+ L L++ N ++++ + +F N+T+L +R NP+ C C
Sbjct 229 YLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD-DLDNITQLILRNNPWYCGC 287
Query 652 ESIAWFVNWINE--THTNIPELSSHYLCNTPPHYHGFPVR 689
+ + W +W+ N+ L +C P G ++
Sbjct 288 K-MKWVRDWLQSLPVKVNVRGL----MCQAPEKVRGMAIK 322
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 31/210 (15%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L NN+ + DS + +P LE L+ N++ + G F R N R
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE--EGAF--RDSNYLRLLFLSRN 140
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS--------- 389
L+++P + + +E L ++DN I I S GL +LK L L +
Sbjct 141 HLSTIP------WGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGD 194
Query 390 --FTSLRTLTNETFV--SLAHSPLHI-------LNLTKNKISKIESDAFSWLGHLEVLDL 438
F +L LT + V SL +P+++ L L N I+++ +AFS+L L LD+
Sbjct 195 KVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 254
Query 439 GLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
N + G + L+NI ++ L N +
Sbjct 255 SNNNLSNLPQGI-FDDLDNITQLILRNNPW 283
Score = 43.1 bits (100), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 41/142 (29%), Positives = 68/142 (48%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ +P LP I L L N++ + + + + L L + N ++ L ++ L
Sbjct 142 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 201
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L+L N L+ TNL +L+L N I ++ N F + L LD+S+N L
Sbjct 202 NLTELSLVRNSLTAAPVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 259
Query 160 SSTKLGTQVQLENLQELLLSNN 181
S+ G L+N+ +L+L NN
Sbjct 260 SNLPQGIFDDLDNITQLILRNN 281
Score = 40.8 bits (94), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 36/221 (16%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS-- 403
+D+F K ++ L++++N+I I + + + L+ L L ++ S ++ F
Sbjct 71 LDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSN 130
Query 404 -----------LAHSP------LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
L+ P + L L N+IS I S + L L+ L L N +
Sbjct 131 YLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNH 190
Query 447 LTGQE-WRGLENIFEIYLSYNKYLQLTRNSFALVP------SLQRLMLRRVALKNVDSSP 499
G + + L N+ E L L RNS P +L++L L+ + V P
Sbjct 191 GLGDKVFFNLVNLTE--------LSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRV--PP 240
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+ F LR L LD+SNNN++N+ + + L+ + L L++N
Sbjct 241 NAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 281
>5cmn_B B Leucine-rich repeat transmembrane protein FLRT3
Length=333
Score = 57.0 bits (136), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 82/311 (26%), Positives = 132/311 (42%), Gaps = 40/311 (13%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLP-AANFTRYSQLTSLD 81
S + C C+ LT +P +P + T L L +NQ+ ++ ++ +
Sbjct 6 SCPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIY 65
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIK 139
+ N++ + L + +K L+LQ N + ++ + + L ELHL NS+ I+
Sbjct 66 LYHNSLDEFPTNLPK---YVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 122
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
F L L LS N LS+ G +E EL L +N+I + S L +SL
Sbjct 123 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIE---ELRLDDNRISTISSPSLQGL--TSL 177
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
K+L L N LNN LG +K+ L N + LSL +
Sbjct 178 KRLVLDGN-------------------LLNNHGLG----DKVFFNLVN--LTELSLVRNS 212
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH 319
L+ + L TNL L L N++N V ++F++L QL + NN+ +L
Sbjct 213 LTAAP----VNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD 268
Query 320 GLFNVRYLNLK 330
L N+ L L+
Sbjct 269 DLDNITQLILR 279
Score = 51.2 bits (121), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 70/280 (25%), Positives = 120/280 (43%), Gaps = 44/280 (16%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L +N I I D+ S + +LE L L N + +I E + YL+L
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAV----------SIEEGAFRDSNYLRL 134
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
L L R L + P+ R + L L +N I+ I+ L+GL
Sbjct 135 -------------LFLSRNHLSTI-----PWGLPRTIEELRLDDNRISTISSPSLQGLTS 176
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L+ L L N L + G ++F L +L L+L N PV + L+ +
Sbjct 177 LKRLVLDGN----LLNNHGLGDKVFF--NLVNLTELSLVRNSLTAAPVNLPGT--NLRKL 228
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTC 651
L N++N +P + F+ L L++ N ++++ + +F N+T+L +R NP+ C C
Sbjct 229 YLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD-DLDNITQLILRNNPWYCGC 287
Query 652 ESIAWFVNWINE--THTNIPELSSHYLCNTPPHYHGFPVR 689
+ + W +W+ N+ L +C P G ++
Sbjct 288 K-MKWVRDWLQSLPVKVNVRGL----MCQAPEKVRGMAIK 322
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 31/210 (15%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L NN+ + DS + +P LE L+ N++ + G F R N R
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE--EGAF--RDSNYLRLLFLSRN 140
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS--------- 389
L+++P + + +E L ++DN I I S GL +LK L L +
Sbjct 141 HLSTIP------WGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGD 194
Query 390 --FTSLRTLTNETFV--SLAHSPLHI-------LNLTKNKISKIESDAFSWLGHLEVLDL 438
F +L LT + V SL +P+++ L L N I+++ +AFS+L L LD+
Sbjct 195 KVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 254
Query 439 GLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
N + G + L+NI ++ L N +
Sbjct 255 SNNNLSNLPQGI-FDDLDNITQLILRNNPW 283
Score = 43.1 bits (100), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 41/142 (29%), Positives = 68/142 (48%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ +P LP I L L N++ + + + + L L + N ++ L ++ L
Sbjct 142 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 201
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L+L N L+ TNL +L+L N I ++ N F + L LD+S+N L
Sbjct 202 NLTELSLVRNSLTAAPVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 259
Query 160 SSTKLGTQVQLENLQELLLSNN 181
S+ G L+N+ +L+L NN
Sbjct 260 SNLPQGIFDDLDNITQLILRNN 281
Score = 40.8 bits (94), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 36/221 (16%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS-- 403
+D+F K ++ L++++N+I I + + + L+ L L ++ S ++ F
Sbjct 71 LDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSN 130
Query 404 -----------LAHSP------LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
L+ P + L L N+IS I S + L L+ L L N +
Sbjct 131 YLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNH 190
Query 447 LTGQE-WRGLENIFEIYLSYNKYLQLTRNSFALVP------SLQRLMLRRVALKNVDSSP 499
G + + L N+ E L L RNS P +L++L L+ + V P
Sbjct 191 GLGDKVFFNLVNLTE--------LSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRV--PP 240
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+ F LR L LD+SNNN++N+ + + L+ + L L++N
Sbjct 241 NAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 281
>5cmn_A A Leucine-rich repeat transmembrane protein FLRT3
Length=333
Score = 57.0 bits (136), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 82/311 (26%), Positives = 132/311 (42%), Gaps = 40/311 (13%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLP-AANFTRYSQLTSLD 81
S + C C+ LT +P +P + T L L +NQ+ ++ ++ +
Sbjct 6 SCPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIY 65
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIK 139
+ N++ + L + +K L+LQ N + ++ + + L ELHL NS+ I+
Sbjct 66 LYHNSLDEFPTNLPK---YVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 122
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
F L L LS N LS+ G +E EL L +N+I + S L +SL
Sbjct 123 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIE---ELRLDDNRISTISSPSLQGL--TSL 177
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
K+L L N LNN LG +K+ L N + LSL +
Sbjct 178 KRLVLDGN-------------------LLNNHGLG----DKVFFNLVN--LTELSLVRNS 212
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH 319
L+ + L TNL L L N++N V ++F++L QL + NN+ +L
Sbjct 213 LTAAP----VNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD 268
Query 320 GLFNVRYLNLK 330
L N+ L L+
Sbjct 269 DLDNITQLILR 279
Score = 51.2 bits (121), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 70/280 (25%), Positives = 120/280 (43%), Gaps = 44/280 (16%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L +N I I D+ S + +LE L L N + +I E + YL+L
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAV----------SIEEGAFRDSNYLRL 134
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
L L R L + P+ R + L L +N I+ I+ L+GL
Sbjct 135 -------------LFLSRNHLSTI-----PWGLPRTIEELRLDDNRISTISSPSLQGLTS 176
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L+ L L N L + G ++F L +L L+L N PV + L+ +
Sbjct 177 LKRLVLDGN----LLNNHGLGDKVFF--NLVNLTELSLVRNSLTAAPVNLPGT--NLRKL 228
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTC 651
L N++N +P + F+ L L++ N ++++ + +F N+T+L +R NP+ C C
Sbjct 229 YLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD-DLDNITQLILRNNPWYCGC 287
Query 652 ESIAWFVNWINE--THTNIPELSSHYLCNTPPHYHGFPVR 689
+ + W +W+ N+ L +C P G ++
Sbjct 288 K-MKWVRDWLQSLPVKVNVRGL----MCQAPEKVRGMAIK 322
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 31/210 (15%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L NN+ + DS + +P LE L+ N++ + G F R N R
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE--EGAF--RDSNYLRLLFLSRN 140
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS--------- 389
L+++P + + +E L ++DN I I S GL +LK L L +
Sbjct 141 HLSTIP------WGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGD 194
Query 390 --FTSLRTLTNETFV--SLAHSPLHI-------LNLTKNKISKIESDAFSWLGHLEVLDL 438
F +L LT + V SL +P+++ L L N I+++ +AFS+L L LD+
Sbjct 195 KVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 254
Query 439 GLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
N + G + L+NI ++ L N +
Sbjct 255 SNNNLSNLPQGI-FDDLDNITQLILRNNPW 283
Score = 43.1 bits (100), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 41/142 (29%), Positives = 68/142 (48%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ +P LP I L L N++ + + + + L L + N ++ L ++ L
Sbjct 142 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 201
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L+L N L+ TNL +L+L N I ++ N F + L LD+S+N L
Sbjct 202 NLTELSLVRNSLTAAPVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 259
Query 160 SSTKLGTQVQLENLQELLLSNN 181
S+ G L+N+ +L+L NN
Sbjct 260 SNLPQGIFDDLDNITQLILRNN 281
Score = 40.8 bits (94), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 36/221 (16%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS-- 403
+D+F K ++ L++++N+I I + + + L+ L L ++ S ++ F
Sbjct 71 LDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSN 130
Query 404 -----------LAHSP------LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
L+ P + L L N+IS I S + L L+ L L N +
Sbjct 131 YLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNH 190
Query 447 LTGQE-WRGLENIFEIYLSYNKYLQLTRNSFALVP------SLQRLMLRRVALKNVDSSP 499
G + + L N+ E L L RNS P +L++L L+ + V P
Sbjct 191 GLGDKVFFNLVNLTE--------LSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRV--PP 240
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+ F LR L LD+SNNN++N+ + + L+ + L L++N
Sbjct 241 NAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 281
>5y31_D D Leucine-rich glioma-inactivated protein 1
Length=544
Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 40/135 (30%), Positives = 66/135 (49%), Gaps = 9/135 (7%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 73 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 132
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 133 TLPKDIF-KGLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 186
Query 684 HGFPVRLFDTSSCKD 698
R ++ S KD
Sbjct 187 KK---RKINSLSSKD 198
Score = 47.0 bits (110), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 36/114 (32%), Positives = 63/114 (55%), Gaps = 11/114 (10%)
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
+LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NNI+
Sbjct 51 SLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIK 108
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
+ H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 109 SISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 153
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 56/120 (47%), Gaps = 10/120 (8%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
P + L R + F P +L +L ++N+ I+DD GL LE L +++
Sbjct 47 PDVISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIEN 104
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN+ + +H +GL L L+L +N +P ++FK L L +DL N+ N
Sbjct 105 NNIKSISRHT--------FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 156
Score = 42.4 bits (98), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query 468 YLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLE 527
+ +++ SF PSLQ L+ + + S F L +L L + NNNI +I+
Sbjct 59 FTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENNNIKSISRHTFR 116
Query 528 GLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 117 GLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNSFN 156
Score = 38.1 bits (87), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (3%)
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N + ++ ++F +P L+ L + +K++ S F+ L++L L L+NNN+ + D+
Sbjct 81 NSFDVISDDAFIGLPHLEYLFIENNNIKSI--SRHTFRGLKSLIHLSLANNNLQTLPKDI 138
Query 526 LEGLEKLEILDLQHNNL 542
+GL+ L +DL+ N+
Sbjct 139 FKGLDSLTNVDLRGNSF 155
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 47 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 106
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 107 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 153
Score = 35.0 bits (79), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 26/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 73 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 131
Query 469 LQLTRNSFALVPSLQRLMLR 488
L ++ F + SL + LR
Sbjct 132 QTLPKDIFKGLDSLTNVDLR 151
Score = 35.0 bits (79), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
S I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F
Sbjct 82 SFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIF 139
Query 402 VSL 404
L
Sbjct 140 KGL 142
Score = 34.7 bits (78), Expect = 4.9, Method: Compositional matrix adjust.
Identities = 48/208 (23%), Positives = 90/208 (43%), Gaps = 26/208 (13%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 40 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 99
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 100 LFIENN--NIKSISRHTFRGLK-SLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNSF 155
Query 444 GQELTGQ---EWRGLEN--IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS 498
+ + EW G N + +IY P ++ + ++ K+ D
Sbjct 156 NCDCKLKWLVEWLGHTNATVEDIYCE-------------GPPEYKKRKINSLSSKDFDCI 202
Query 499 PSPFQPLRNLTILDLSNNNIANINDDML 526
+ F ++L LS + + +ND+ +
Sbjct 203 ITEFAKSQDLPYQSLSIDTFSYLNDEYV 230
>5y31_B B Leucine-rich glioma-inactivated protein 1
Length=544
Score = 57.8 bits (138), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 40/135 (30%), Positives = 66/135 (49%), Gaps = 9/135 (7%)
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L +L SN FD I + F L L+ + + NN+ ++ F SL L+L N +
Sbjct 73 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQ 132
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHY 683
++ K +F +LT +D+R N F+C C+ + W V W+ T+ + ++ C PP Y
Sbjct 133 TLPKDIF-KGLDSLTNVDLRGNSFNCDCK-LKWLVEWLGHTNATVEDI----YCEGPPEY 186
Query 684 HGFPVRLFDTSSCKD 698
R ++ S KD
Sbjct 187 KK---RKINSLSSKD 198
Score = 47.0 bits (110), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 36/114 (32%), Positives = 63/114 (55%), Gaps = 11/114 (10%)
Query 252 NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQ 311
+LS S + S +FL +L +L + N+ +V+ +D+F LP LEY F+E NNI+
Sbjct 51 SLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIK 108
Query 312 HLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDN 365
+ H+ GL ++ +L+L + +L +LPK D F+ L L ++++ N
Sbjct 109 SISRHTFRGLKSLIHLSLANN------NLQTLPK--DI-FKGLDSLTNVDLRGN 153
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 56/120 (47%), Gaps = 10/120 (8%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
P + L R + F P +L +L ++N+ I+DD GL LE L +++
Sbjct 47 PDVISLSFVRSGFTEISEGSFLFTP--SLQLLLFTSNSFDVISDDAFIGLPHLEYLFIEN 104
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN+ + +H +GL L L+L +N +P ++FK L L +DL N+ N
Sbjct 105 NNIKSISRHT--------FRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFN 156
Score = 42.4 bits (98), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query 468 YLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLE 527
+ +++ SF PSLQ L+ + + S F L +L L + NNNI +I+
Sbjct 59 FTEISEGSFLFTPSLQLLLFTSNSFDVI--SDDAFIGLPHLEYLFIENNNIKSISRHTFR 116
Query 528 GLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
GL+ L L L +NNL L P KGL L ++L N F+
Sbjct 117 GLKSLIHLSLANNNLQTL--------PKDIFKGLDSLTNVDLRGNSFN 156
Score = 38.1 bits (87), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 22/77 (29%), Positives = 45/77 (58%), Gaps = 2/77 (3%)
Query 466 NKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
N + ++ ++F +P L+ L + +K++ S F+ L++L L L+NNN+ + D+
Sbjct 81 NSFDVISDDAFIGLPHLEYLFIENNNIKSI--SRHTFRGLKSLIHLSLANNNLQTLPKDI 138
Query 526 LEGLEKLEILDLQHNNL 542
+GL+ L +DL+ N+
Sbjct 139 FKGLDSLTNVDLRGNSF 155
Score = 37.0 bits (84), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 4/110 (4%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L+ + +++S+ +F F +L L SNS I ++ F+ +L L + +N
Sbjct 47 PDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNN 106
Query 159 LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSN 207
+ S T L++L L L+NN +Q L DIF SL ++L N
Sbjct 107 IKSISRHTFRGLKSLIHLSLANNNLQTLPK---DIFKGLDSLTNVDLRGN 153
Score = 35.0 bits (79), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 26/80 (33%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L +L T N I DAF L HLE L + N I + ++ +RGL+++ + L+ N
Sbjct 73 LQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNI-KSISRHTFRGLKSLIHLSLANNNL 131
Query 469 LQLTRNSFALVPSLQRLMLR 488
L ++ F + SL + LR
Sbjct 132 QTLPKDIFKGLDSLTNVDLR 151
Score = 35.0 bits (79), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 2/63 (3%)
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETF 401
S I D +F L LE+L +E+N+I I + F GL +L +LSL+N+ +L+TL + F
Sbjct 82 SFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANN--NLQTLPKDIF 139
Query 402 VSL 404
L
Sbjct 140 KGL 142
Score = 34.7 bits (78), Expect = 4.9, Method: Compositional matrix adjust.
Identities = 48/208 (23%), Positives = 90/208 (43%), Gaps = 26/208 (13%)
Query 328 NLKRSFTKQSISLA----SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKY 383
++ R+ ISL+ +I + SF + L+ L N I + F GL +L+Y
Sbjct 40 SIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEY 99
Query 384 LSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
L + N+ ++++++ TF L S +H L+L N + + D F L L +DL N
Sbjct 100 LFIENN--NIKSISRHTFRGLK-SLIH-LSLANNNLQTLPKDIFKGLDSLTNVDLRGNSF 155
Query 444 GQELTGQ---EWRGLEN--IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS 498
+ + EW G N + +IY P ++ + ++ K+ D
Sbjct 156 NCDCKLKWLVEWLGHTNATVEDIYCE-------------GPPEYKKRKINSLSSKDFDCI 202
Query 499 PSPFQPLRNLTILDLSNNNIANINDDML 526
+ F ++L LS + + +ND+ +
Sbjct 203 ITEFAKSQDLPYQSLSIDTFSYLNDEYV 230
>5mx0_A A Fibromodulin
Length=362
Score = 57.0 bits (136), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 94/183 (51%), Gaps = 11/183 (6%)
Query 39 HLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
H LT++P LP ++ L+L HNQ+ R+P LT+L + N I ++ + + L
Sbjct 150 HNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSM-RGL 208
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
L +L+L +N L ++ D + L +L++ N++ + ++ F L+ + LSHN
Sbjct 209 RSLILLDLSYNHLRKVPD---GLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNS 265
Query 159 LSSTKLGTQV-QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCF 217
L++ L + +L EL LS N++Q + N++L+ L L N+I EFS F
Sbjct 266 LTNNGLASNTFNSSSLLELDLSYNQLQKIPP------VNTNLENLYLQGNRINEFSISSF 319
Query 218 HAI 220
+
Sbjct 320 CTV 322
Score = 46.6 bits (109), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 17/155 (11%)
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
++ R F+ + L+RL L N+ P P R+L L L +N I+ + ++ LEGL
Sbjct 131 KVGRKVFSKLRHLERLYLDH---NNLTRMPGPLP--RSLRELHLDHNQISRVPNNALEGL 185
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
E L L LQHN + + ++GL L +L+L N ++P + L +L
Sbjct 186 ENLTALYLQHNEIQEVGSS---------MRGLRSLILLDLSYNHLRKVPDGLPSALEQLY 236
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+ NN+ T+P S F L + L N +T+
Sbjct 237 MEH---NNVYTVPDSYFRGAPKLLYVRLSHNSLTN 268
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 56/209 (27%), Positives = 90/209 (43%), Gaps = 21/209 (10%)
Query 194 FANSSLKKLELSSNQIKEFSPGCF-HAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRN 252
F S +K + +NQI G F +A G L+ N + K+ +L + +
Sbjct 88 FVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRH--LER 145
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
L L ++ L T G +L L L +N ++ V N++ L L +L++N IQ
Sbjct 146 LYLDHNNL-----TRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQE 200
Query 313 LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKS 372
+ S S+ GL RS +S L K+ D LE L ME N++ +
Sbjct 201 VGS-SMRGL---------RSLILLDLSYNHLRKVPD---GLPSALEQLYMEHNNVYTVPD 247
Query 373 NMFTGLINLKYLSLSNSFTSLRTLTNETF 401
+ F G L Y+ LS++ + L + TF
Sbjct 248 SYFRGAPKLLYVRLSHNSLTNNGLASNTF 276
Score = 41.2 bits (95), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 50/206 (24%), Positives = 84/206 (41%), Gaps = 50/206 (24%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAH---------- 406
++++ ++N I I+ +F L +++L + + + + F L H
Sbjct 93 MKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNN 152
Query 407 ---------SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN 457
L L+L N+IS++ ++A L +L L L NEI QE+ G RGL +
Sbjct 153 LTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEI-QEV-GSSMRGLRS 210
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
+ + LSYN LR+V D PS + L + +NN
Sbjct 211 LILLDLSYNH-------------------LRKVP----DGLPSALEQLY------MEHNN 241
Query 518 IANINDDMLEGLEKLEILDLQHNNLA 543
+ + D G KL + L HN+L
Sbjct 242 VYTVPDSYFRGAPKLLYVRLSHNSLT 267
>5cmp_B B Leucine-rich repeat transmembrane protein FLRT3
Length=333
Score = 57.0 bits (136), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 82/311 (26%), Positives = 132/311 (42%), Gaps = 40/311 (13%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLP-AANFTRYSQLTSLD 81
S + C C+ LT +P +P + T L L +NQ+ ++ ++ +
Sbjct 6 SCPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIY 65
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIK 139
+ N++ + L + +K L+LQ N + ++ + + L ELHL NS+ I+
Sbjct 66 LYHNSLDEFPTNLPK---YVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 122
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
F L L LS N LS+ G +E EL L +N+I + S L +SL
Sbjct 123 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIE---ELRLDDNRISTISSPSLQGL--TSL 177
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
K+L L N LNN LG +K+ L N + LSL +
Sbjct 178 KRLVLDGN-------------------LLNNHGLG----DKVFFNLVN--LTELSLVRNS 212
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH 319
L+ + L TNL L L N++N V ++F++L QL + NN+ +L
Sbjct 213 LTAAP----VNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD 268
Query 320 GLFNVRYLNLK 330
L N+ L L+
Sbjct 269 DLDNITQLILR 279
Score = 51.2 bits (121), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 70/280 (25%), Positives = 120/280 (43%), Gaps = 44/280 (16%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L +N I I D+ S + +LE L L N + +I E + YL+L
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAV----------SIEEGAFRDSNYLRL 134
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
L L R L + P+ R + L L +N I+ I+ L+GL
Sbjct 135 -------------LFLSRNHLSTI-----PWGLPRTIEELRLDDNRISTISSPSLQGLTS 176
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L+ L L N L + G ++F L +L L+L N PV + L+ +
Sbjct 177 LKRLVLDGN----LLNNHGLGDKVFF--NLVNLTELSLVRNSLTAAPVNLPGT--NLRKL 228
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTC 651
L N++N +P + F+ L L++ N ++++ + +F N+T+L +R NP+ C C
Sbjct 229 YLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD-DLDNITQLILRNNPWYCGC 287
Query 652 ESIAWFVNWINE--THTNIPELSSHYLCNTPPHYHGFPVR 689
+ + W +W+ N+ L +C P G ++
Sbjct 288 K-MKWVRDWLQSLPVKVNVRGL----MCQAPEKVRGMAIK 322
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 31/210 (15%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L NN+ + DS + +P LE L+ N++ + G F R N R
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE--EGAF--RDSNYLRLLFLSRN 140
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS--------- 389
L+++P + + +E L ++DN I I S GL +LK L L +
Sbjct 141 HLSTIP------WGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGD 194
Query 390 --FTSLRTLTNETFV--SLAHSPLHI-------LNLTKNKISKIESDAFSWLGHLEVLDL 438
F +L LT + V SL +P+++ L L N I+++ +AFS+L L LD+
Sbjct 195 KVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 254
Query 439 GLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
N + G + L+NI ++ L N +
Sbjct 255 SNNNLSNLPQGI-FDDLDNITQLILRNNPW 283
Score = 43.1 bits (100), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 41/142 (29%), Positives = 68/142 (48%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ +P LP I L L N++ + + + + L L + N ++ L ++ L
Sbjct 142 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 201
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L+L N L+ TNL +L+L N I ++ N F + L LD+S+N L
Sbjct 202 NLTELSLVRNSLTAAPVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 259
Query 160 SSTKLGTQVQLENLQELLLSNN 181
S+ G L+N+ +L+L NN
Sbjct 260 SNLPQGIFDDLDNITQLILRNN 281
Score = 40.8 bits (94), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 36/221 (16%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS-- 403
+D+F K ++ L++++N+I I + + + L+ L L ++ S ++ F
Sbjct 71 LDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSN 130
Query 404 -----------LAHSP------LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
L+ P + L L N+IS I S + L L+ L L N +
Sbjct 131 YLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNH 190
Query 447 LTGQE-WRGLENIFEIYLSYNKYLQLTRNSFALVP------SLQRLMLRRVALKNVDSSP 499
G + + L N+ E L L RNS P +L++L L+ + V P
Sbjct 191 GLGDKVFFNLVNLTE--------LSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRV--PP 240
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+ F LR L LD+SNNN++N+ + + L+ + L L++N
Sbjct 241 NAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 281
>7w3x_A C Membrane-localized LRR receptor-like protein
Length=934
Score = 58.2 bits (139), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 117/476 (25%), Positives = 200/476 (42%), Gaps = 77/476 (16%)
Query 244 ELANTSIRNLS---LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQL 300
E+AN+S+ +LS L ++ S+++ ++L T+LT +DLS N L+ +D F L L
Sbjct 231 EIANSSLISLSVLHLCCNEFSSSAKYSWLFNFSTSLTSIDLSNNQLDGQIDDRFGNLMYL 290
Query 301 EYFFLEYN-NIQHLFSHSLHGLFNVRYLNLKRSFTKQSI------------SLASLPKID 347
E+ L N++ S L +RYL++ + T Q + +L L D
Sbjct 291 EHLNLANELNLKGGIPSSFGNLTRLRYLDMSNTRTYQWLPELFVRLSGSRKTLEVLGLND 350
Query 348 DFSFQWL------KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS-----------F 390
+ F L L+ L ++ N + G F + +L+YL LS++ F
Sbjct 351 NSMFGSLVDVTRFSALKRLYLQKNVLNGFFMERFGQVSSLEYLDLSDNQMRGPLPDLALF 410
Query 391 TSLRTL---TNETFVSLAH-----SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE 442
SLR L +N + S L IL+++ N++ + ++ L +LE D N
Sbjct 411 PSLRELHLGSNHFNGRIPQGIGKLSQLKILDVSSNRLEGLP-ESMGQLSNLESFDASYNV 469
Query 443 IGQELTGQEWRGLENIFEIYLSYNKYLQLTR--------------NSFALVPSLQRLMLR 488
+ +T L ++ ++ LS+N T S L PS + +
Sbjct 470 LKGTITESHLSNLSSLVDLDLSFNSLALKTSIDWLPPFQLQVINLPSCNLGPSFPKWLQS 529
Query 489 R-------VALKNV-DSSPSPFQPLR-NLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
+ ++L N+ D+ PS F L ++ IL+LSNN I+ D++E ++DL
Sbjct 530 QNNYTVLDISLANISDALPSWFSGLPPDIKILNLSNNQISGRVSDLIENAYDYMVIDLSS 589
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN + GP+ + +++ I L N F + K +DL N +
Sbjct 590 NNFS---------GPLPLVP--TNVQIFYLHKNQFFGSISSICKSTTGATSLDLSHNQFS 638
Query 600 TLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIA 655
+ N +L LNL N + + G + NL L MR N F S++
Sbjct 639 GELPDCWMNATNLAVLNLAYNNFSGKLPQSLG-SLTNLEALYMRQNSFSGMLPSLS 693
Score = 48.1 bits (113), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 135/551 (25%), Positives = 226/551 (41%), Gaps = 93/551 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
+++ L+L+ NQ+R P + + L L +G N + P+ KL LK+L++ N
Sbjct 388 SSLEYLDLSDNQMRG-PLPDLALFPSLRELHLGSNHFNGRIPQGIGKLSQLKILDVSSNR 446
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQK-IKNNPFVKQKNLITLDLSHNGLS-STKLG--- 165
L L + + +NL N ++ I + +L+ LDLS N L+ T +
Sbjct 447 LEGLPE-SMGQLSNLESFDASYNVLKGTITESHLSNLSSLVDLDLSFNSLALKTSIDWLP 505
Query 166 -TQVQLENLQELLLSNNKIQALKSEE----LDI-FANSS-------------LKKLELSS 206
Q+Q+ NL L + + L+S+ LDI AN S +K L LS+
Sbjct 506 PFQLQVINLPSCNLGPSFPKWLQSQNNYTVLDISLANISDALPSWFSGLPPDIKILNLSN 565
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRN---LSLSNSQLSTT 263
NQI GR+ L N + + ++L++ + L +N Q+
Sbjct 566 NQIS----------GRVSDLIENAY-------DYMVIDLSSNNFSGPLPLVPTNVQIFYL 608
Query 264 SNTTFLG------LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHS 317
F G T T LDLS+N + D + L L YNN S
Sbjct 609 HKNQFFGSISSICKSTTGATSLDLSHNQFSGELPDCWMNATNLAVLNLAYNNFSGKLPQS 668
Query 318 LHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG-IKSNMFT 376
L L N+ L + +Q+ LP S + L+ L++ N + G I + + T
Sbjct 669 LGSLTNLEAL-----YMRQNSFSGMLP-----SLSQCQSLQILDLGGNKLTGRIPAWIGT 718
Query 377 GLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKIS-KIES--DAFSWLGHL 433
L+NL+ LSL F + L L IL+L+ N ++ KI + F+ L
Sbjct 719 DLLNLRILSLR--FNKFYGSISPIICQLQF--LQILDLSANGLAGKIPQCFNNFTLLHQE 774
Query 434 EVLDLGLNEIGQELTGQ-------------EWRGLENIFEIYLSYNKYLQLTRNSFALVP 480
L + + Q G+ +W+ E ++ L+Y K + L+ N LV
Sbjct 775 NGLGEPMEFLVQGFYGKYPRHYSYLGNLLVQWKNQEAEYKNPLTYLKTIDLSSN--KLVG 832
Query 481 SLQRLMLRRVALKNVDSSPSPFQP--------LRNLTILDLSNNNIANINDDMLEGLEKL 532
+ + M LK+++ S + ++ L LDLS N ++ + L L +
Sbjct 833 GIPKEMAEMRGLKSLNLSRNDLNGSIIKGIGQMKMLESLDLSRNQLSGMIPKDLANLTFI 892
Query 533 EILDLQHNNLA 543
+LDL +N+L+
Sbjct 893 GVLDLSNNHLS 903
Score = 43.1 bits (100), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 138/553 (25%), Positives = 218/553 (39%), Gaps = 105/553 (19%)
Query 69 ANFTRYSQLTSLDVGFNTISKLEPELCQKLP----MLKVLNLQHNEL-SQLSDKTFAFCT 123
++F ++L LD+ + PEL +L L+VL L N + L D T +
Sbjct 307 SSFGNLTRLRYLDMSNTRTYQWLPELFVRLSGSRKTLEVLGLNDNSMFGSLVDVTRF--S 364
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
L L+L N + F + +L LDLS N + L +L+EL L +N
Sbjct 365 ALKRLYLQKNVLNGFFMERFGQVSSLEYLDLSDNQMRG-PLPDLALFPSLRELHLGSNHF 423
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCL 243
+ + S LK L++SSN+++ G ++G+L L E
Sbjct 424 NGRIPQGIGKL--SQLKILDVSSNRLE----GLPESMGQLSNL------------ESFD- 464
Query 244 ELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLP--QLE 301
A+ ++ +++ S LS S+ L LDLS+N+L + S WLP QL+
Sbjct 465 --ASYNVLKGTITESHLSNLSS----------LVDLDLSFNSLAL--KTSIDWLPPFQLQ 510
Query 302 YFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCL---- 357
L N+ F ++L + ++T ISLA+ I D W L
Sbjct 511 VINLPSCNLGPSFP---------KWLQSQNNYTVLDISLAN---ISDALPSWFSGLPPDI 558
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETFVSLAHSPLHILNLTK 416
+ LN+ +N I G S++ + + LS N+F+ + L + + I L K
Sbjct 559 KILNLSNNQISGRVSDLIENAYDYMVIDLSSNNFSGP--------LPLVPTNVQIFYLHK 610
Query 417 NKI-SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNS 475
N+ I S S G LDL N+ EL W N+ + L+YN + S
Sbjct 611 NQFFGSISSICKSTTGATS-LDLSHNQFSGELP-DCWMNATNLAVLNLAYNNFSGKLPQS 668
Query 476 FALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEIL 535
+ +L+ L +R+ + + S S Q L+ ILDL N +
Sbjct 669 LGSLTNLEALYMRQNSFSGMLPSLSQCQSLQ---ILDLGGNKLT---------------- 709
Query 536 DLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGL 595
R+ P + L +L IL+L N F + L L+I+DL
Sbjct 710 -------GRI--------PAWIGTDLLNLRILSLRFNKFYGSISPIICQLQFLQILDLSA 754
Query 596 NNLNTLPASVFNN 608
N L FNN
Sbjct 755 NGLAGKIPQCFNN 767
Score = 42.4 bits (98), Expect = 0.024, Method: Compositional matrix adjust.
Identities = 53/174 (30%), Positives = 78/174 (45%), Gaps = 10/174 (6%)
Query 49 LPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQH 108
+PTN+ + L NQ ++ + TSLD+ N S P+ L VLNL +
Sbjct 599 VPTNVQIFYLHKNQFFGSISSICKSTTGATSLDLSHNQFSGELPDCWMNATNLAVLNLAY 658
Query 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ-KNLITLDLSHNGLSS---TKL 164
N S ++ TNL L++ NS + P + Q ++L LDL N L+ +
Sbjct 659 NNFSGKLPQSLGSLTNLEALYMRQNSFSGML--PSLSQCQSLQILDLGGNKLTGRIPAWI 716
Query 165 GTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFH 218
GT L NL+ L L NK S I L+ L+LS+N + P CF+
Sbjct 717 GT--DLLNLRILSLRFNKFYGSISPI--ICQLQFLQILDLSANGLAGKIPQCFN 766
>4p91_A A Reticulon-4 receptor-like 2
Length=302
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 59/227 (26%), Positives = 88/227 (39%), Gaps = 37/227 (16%)
Query 499 PSPFQPLRNLTILDLSNN-NIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF 557
P F+ L+ L LDL +N ++ ++ D +GLE+L+ L L L+ L P
Sbjct 71 PGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSL--------PGNI 122
Query 558 LKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
+GL L L L+ N + ++F DL L + L N L L VF SL L L
Sbjct 123 FRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLL 182
Query 618 QKNLITSVEKKVF--------------------GPAFRNLTELD---MRFNPFDCTCESI 654
N + V + F G A +L L+ + NP+ C C +
Sbjct 183 HGNRLQGVHRAAFHGLSRLTILYLFNNSLASLPGEALADLPALEFLRLNANPWACDCRAR 242
Query 655 AWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSCKDSAP 701
+ W + SS C TPP G +R + + P
Sbjct 243 PLWA-WFQRARVS----SSDVTCATPPERQGRDLRTLRDTDFQACPP 284
Score = 56.2 bits (134), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 57/183 (31%), Positives = 82/183 (45%), Gaps = 10/183 (5%)
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
L N +S I F L LE LDLG N + L ++GLE + ++L + L
Sbjct 61 LFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPG 120
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
N F + SLQ L L+ +L ++ F L NL+ L L N + + + + GL L+
Sbjct 121 NIFRGLVSLQYLYLQENSLLHLQD--DLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLD 178
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
L L N L + + A GLS L IL L +N +P E DL L+ + L
Sbjct 179 RLLLHGNRLQGVHRAA--------FHGLSRLTILYLFNNSLASLPGEALADLPALEFLRL 230
Query 594 GLN 596
N
Sbjct 231 NAN 233
Score = 53.9 bits (128), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 63/218 (29%), Positives = 90/218 (41%), Gaps = 12/218 (6%)
Query 19 MLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLT 78
MLC ++ TVS C + VP LP + L L +N +R L F L
Sbjct 5 MLCTCYSSPPTVS-----CQANNFSSVPLSLPPSTQRLFLQNNLIRSLRPGTFG--PNLL 57
Query 79 SLDVGFNTISKLEPELCQKLPMLKVLNLQHNE-LSQLSDKTFAFCTNLTELHLMSNSIQK 137
+L + N +S + P + L L+ L+L N L L TF L LHL +
Sbjct 58 TLWLFSNNLSTIYPGTFRHLQALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSS 117
Query 138 IKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN- 196
+ N F +L L L N L + L NL L L N+++ L +F
Sbjct 118 LPGNIFRGLVSLQYLYLQENSLLHLQDDLFADLANLSHLFLHGNRLRLLTEH---VFRGL 174
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLG 234
SL +L L N+++ FH + RL L+L N L
Sbjct 175 GSLDRLLLHGNRLQGVHRAAFHGLSRLTILYLFNNSLA 212
Score = 47.0 bits (110), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 68/212 (32%), Positives = 95/212 (45%), Gaps = 12/212 (6%)
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
P + L LQ+N + L TF NL L L SN++ I F + L LDL N
Sbjct 32 PSTQRLFLQNNLIRSLRPGTFG--PNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDNR 89
Query 159 -LSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGC 216
L S + T LE LQ L L ++ +L +IF SL+ L L N +
Sbjct 90 HLRSLEPDTFQGLERLQSLHLYRCQLSSLPG---NIFRGLVSLQYLYLQENSLLHLQDDL 146
Query 217 FHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNL 276
F + L LFL+ +L LTE + L S+ L L ++L F GL + L
Sbjct 147 FADLANLSHLFLHGNRLR-LLTEHVFRGLG--SLDRLLLHGNRLQGVHRAAFHGL--SRL 201
Query 277 TMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
T+L L N+L + ++ A LP LE+ L N
Sbjct 202 TILYLFNNSLASLPGEALADLPALEFLRLNAN 233
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 42/138 (30%), Positives = 70/138 (51%), Gaps = 5/138 (4%)
Query 350 SFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPL 409
+FQ L+ L+ L++ + + N+F GL++L+YL L + SL L ++ F LA+ L
Sbjct 98 TFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQEN--SLLHLQDDLFADLAN--L 153
Query 410 HILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
L L N++ + F LG L+ L L N + Q + + GL + +YL N
Sbjct 154 SHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRL-QGVHRAAFHGLSRLTILYLFNNSLA 212
Query 470 QLTRNSFALVPSLQRLML 487
L + A +P+L+ L L
Sbjct 213 SLPGEALADLPALEFLRL 230
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 69/239 (29%), Positives = 104/239 (44%), Gaps = 13/239 (5%)
Query 92 PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
P LC ++ Q N S + + + L L +N I+ ++ F NL+T
Sbjct 4 PMLCTCYSSPPTVSCQANNFSSVP---LSLPPSTQRLFLQNNLIRSLRPGTF--GPNLLT 58
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIK 210
L L N LS+ GT L+ L+EL L +N+ L+S E D F L+ L L Q+
Sbjct 59 LWLFSNNLSTIYPGTFRHLQALEELDLGDNR--HLRSLEPDTFQGLERLQSLHLYRCQLS 116
Query 211 EFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLG 270
F + L L+L L L + L +LAN S +L L ++L + F G
Sbjct 117 SLPGNIFRGLVSLQYLYLQENSLL-HLQDDLFADLANLS--HLFLHGNRLRLLTEHVFRG 173
Query 271 LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
L +L L L N L V +F L +L +L N++ L +L L + +L L
Sbjct 174 LG--SLDRLLLHGNRLQGVHRAAFHGLSRLTILYLFNNSLASLPGEALADLPALEFLRL 230
Score = 40.0 bits (92), Expect = 0.085, Method: Compositional matrix adjust.
Identities = 47/153 (31%), Positives = 67/153 (44%), Gaps = 3/153 (2%)
Query 56 LNLTHNQ-LRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
L+L N+ LR L F +L SL + +S L + + L L+ L LQ N L L
Sbjct 83 LDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGNIFRGLVSLQYLYLQENSLLHL 142
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
D FA NL+ L L N ++ + + F +L L L N L L L
Sbjct 143 QDDLFADLANLSHLFLHGNRLRLLTEHVFRGLGSLDRLLLHGNRLQGVHRAAFHGLSRLT 202
Query 175 ELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
L L NN + +L E L +L+ L L++N
Sbjct 203 ILYLFNNSLASLPGEALADLP--ALEFLRLNAN 233
Score = 37.4 bits (85), Expect = 0.61, Method: Compositional matrix adjust.
Identities = 66/245 (27%), Positives = 102/245 (42%), Gaps = 45/245 (18%)
Query 198 SLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSN 257
S ++L L +N I+ PG F GP+L L L +
Sbjct 33 STQRLFLQNNLIRSLRPGTF----------------GPNLL-------------TLWLFS 63
Query 258 SQLSTTSNTTFLGLKWTNLTMLDLSYN-NLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
+ LST TF L+ L LDL N +L + D+F L +L+ L + L +
Sbjct 64 NNLSTIYPGTFRHLQ--ALEELDLGDNRHLRSLEPDTFQGLERLQSLHLYRCQLSSLPGN 121
Query 317 SLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFT 376
GL +++YL L+ + SL + D F L L HL + N + + ++F
Sbjct 122 IFRGLVSLQYLYLQEN---------SLLHLQDDLFADLANLSHLFLHGNRLRLLTEHVFR 172
Query 377 GLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVL 436
GL +L L L + L+ + F L+ L IL L N ++ + +A + L LE L
Sbjct 173 GLGSLDRLLLHGN--RLQGVHRAAFHGLSR--LTILYLFNNSLASLPGEALADLPALEFL 228
Query 437 DLGLN 441
L N
Sbjct 229 RLNAN 233
>7yo4_B B Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.073, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7yo4_F F Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.073, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7yo4_H H Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.073, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7yo4_D D Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.073, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>5cmp_A A Leucine-rich repeat transmembrane protein FLRT3
Length=333
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 82/311 (26%), Positives = 132/311 (42%), Gaps = 40/311 (13%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLP-AANFTRYSQLTSLD 81
S + C C+ LT +P +P + T L L +NQ+ ++ ++ +
Sbjct 6 SCPSVCRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIY 65
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIK 139
+ N++ + L + +K L+LQ N + ++ + + L ELHL NS+ I+
Sbjct 66 LYHNSLDEFPTNLPK---YVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 122
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
F L L LS N LS+ G +E EL L +N+I + S L +SL
Sbjct 123 EGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIE---ELRLDDNRISTISSPSLQGL--TSL 177
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
K+L L N LNN LG +K+ L N + LSL +
Sbjct 178 KRLVLDGN-------------------LLNNHGLG----DKVFFNLVN--LTELSLVRNS 212
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH 319
L+ + L TNL L L N++N V ++F++L QL + NN+ +L
Sbjct 213 LTAAP----VNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD 268
Query 320 GLFNVRYLNLK 330
L N+ L L+
Sbjct 269 DLDNITQLILR 279
Score = 50.8 bits (120), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 70/280 (25%), Positives = 120/280 (43%), Gaps = 44/280 (16%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L +N I I D+ S + +LE L L N + +I E + YL+L
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAV----------SIEEGAFRDSNYLRL 134
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
L L R L + P+ R + L L +N I+ I+ L+GL
Sbjct 135 -------------LFLSRNHLSTI-----PWGLPRTIEELRLDDNRISTISSPSLQGLTS 176
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L+ L L N L + G ++F L +L L+L N PV + L+ +
Sbjct 177 LKRLVLDGN----LLNNHGLGDKVFF--NLVNLTELSLVRNSLTAAPVNLPGT--NLRKL 228
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTC 651
L N++N +P + F+ L L++ N ++++ + +F N+T+L +R NP+ C C
Sbjct 229 YLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD-DLDNITQLILRNNPWYCGC 287
Query 652 ESIAWFVNWINE--THTNIPELSSHYLCNTPPHYHGFPVR 689
+ + W +W+ N+ L +C P G ++
Sbjct 288 K-MKWVRDWLQSLPVKVNVRGL----MCQAPEKVRGMAIK 322
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 31/210 (15%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L NN+ + DS + +P LE L+ N++ + G F R N R
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE--EGAF--RDSNYLRLLFLSRN 140
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS--------- 389
L+++P + + +E L ++DN I I S GL +LK L L +
Sbjct 141 HLSTIP------WGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGD 194
Query 390 --FTSLRTLTNETFV--SLAHSPLHI-------LNLTKNKISKIESDAFSWLGHLEVLDL 438
F +L LT + V SL +P+++ L L N I+++ +AFS+L L LD+
Sbjct 195 KVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 254
Query 439 GLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
N + G + L+NI ++ L N +
Sbjct 255 SNNNLSNLPQGI-FDDLDNITQLILRNNPW 283
Score = 43.1 bits (100), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 41/142 (29%), Positives = 68/142 (48%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ +P LP I L L N++ + + + + L L + N ++ L ++ L
Sbjct 142 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 201
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L+L N L+ TNL +L+L N I ++ N F + L LD+S+N L
Sbjct 202 NLTELSLVRNSLTAAPVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 259
Query 160 SSTKLGTQVQLENLQELLLSNN 181
S+ G L+N+ +L+L NN
Sbjct 260 SNLPQGIFDDLDNITQLILRNN 281
Score = 40.8 bits (94), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 36/221 (16%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS-- 403
+D+F K ++ L++++N+I I + + + L+ L L ++ S ++ F
Sbjct 71 LDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSN 130
Query 404 -----------LAHSP------LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
L+ P + L L N+IS I S + L L+ L L N +
Sbjct 131 YLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNH 190
Query 447 LTGQE-WRGLENIFEIYLSYNKYLQLTRNSFALVP------SLQRLMLRRVALKNVDSSP 499
G + + L N+ E L L RNS P +L++L L+ + V P
Sbjct 191 GLGDKVFFNLVNLTE--------LSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRV--PP 240
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+ F LR L LD+SNNN++N+ + + L+ + L L++N
Sbjct 241 NAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 281
>2ft3_D D Biglycan
Length=332
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 50/187 (27%), Positives = 88/187 (47%), Gaps = 11/187 (6%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI--SKLEPELCQKLP 99
L ++P +LP+++ L + N++R++P F+ + +++G N + S EP L
Sbjct 114 LVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGL- 172
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L + +L+ + L ELHL N IQ I+ ++ L L L HN +
Sbjct 173 KLNYLRISEAKLTGIPKD---LPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQI 229
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
+ G+ L L+EL L NNK+ + + D+ L+ + L +N I + F
Sbjct 230 RMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDL---KLLQVVYLHTNNITKVGVNDFCP 286
Query 220 IGRLFGL 226
+G FG+
Sbjct 287 VG--FGV 291
Score = 54.7 bits (130), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/106 (34%), Positives = 58/106 (55%), Gaps = 1/106 (1%)
Query 38 SHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
S KLT +P DLP + L+L HN+++ + + RYS+L L +G N I +E
Sbjct 180 SEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF 239
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
LP L+ L+L +N+LS++ L ++L +N+I K+ N F
Sbjct 240 LPTLRELHLDNNKLSRVP-AGLPDLKLLQVVYLHTNNITKVGVNDF 284
Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 65/264 (25%), Positives = 101/264 (38%), Gaps = 78/264 (30%)
Query 13 GLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFT 72
+ PFG C V CS L L VP ++ + T+L+L +N + L +F
Sbjct 25 AMCPFG---------CHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDF- 74
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA------------ 120
+ L L L L +N++S++ +K F+
Sbjct 75 -----------------------KGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISK 111
Query 121 ---------FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL------------ 159
++L EL + N I+K+ F +N+ +++ N L
Sbjct 112 NHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDG 171
Query 160 --------SSTKL-GTQVQL-ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
S KL G L E L EL L +NKIQA++ E D+ S L +L L NQI
Sbjct 172 LKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELE--DLLRYSKLYRLGLGHNQI 229
Query 210 KEFSPGCFHAIGRLFGLFLNNVQL 233
+ G + L L L+N +L
Sbjct 230 RMIENGSLSFLPTLRELHLDNNKL 253
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 41/157 (26%), Positives = 69/157 (44%), Gaps = 14/157 (9%)
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILD 536
A+ P LR V ++ P + + T+LDL NN+I+ + D +GL+ L L
Sbjct 25 AMCPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV 84
Query 537 LQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L +N ++++ + A L L L + N EIP + L EL+I D N
Sbjct 85 LVNNKISKIHEKA--------FSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHD---N 133
Query 597 NLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPA 633
+ +P VF+ ++ + + N +E F P
Sbjct 134 RIRKVPKGVFSGLRNMNCIEMGGN---PLENSGFEPG 167
Score = 42.4 bits (98), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 32/262 (12%)
Query 269 LGLKWT------NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
LGLK + T+LDL N+++ + D F L L L N I + + L
Sbjct 43 LGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPL- 101
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
R K IS L +I L L + DN I + +F+GL N+
Sbjct 102 --------RKLQKLYISKNHLVEIPP---NLPSSLVELRIHDNRIRKVPKGVFSGLRNMN 150
Query 383 YLSLSNSFTSLRTLTNETFVSLAHSPLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGL 440
+ + + L N F A L + L +++ K++ I D L L L
Sbjct 151 CIEMGGN-----PLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELH---LDH 202
Query 441 NEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPS 500
N+I Q + ++ ++ + L +N+ + S + +P+L+ L L L V P+
Sbjct 203 NKI-QAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRV---PA 258
Query 501 PFQPLRNLTILDLSNNNIANIN 522
L+ L ++ L NNI +
Sbjct 259 GLPDLKLLQVVYLHTNNITKVG 280
Score = 41.2 bits (95), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 62/230 (27%), Positives = 101/230 (44%), Gaps = 33/230 (14%)
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN---EIGQELTGQEW 452
L + F L H L+ L L NKISKI AFS L L+ L + N EI L
Sbjct 69 LRKDDFKGLQH--LYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLP---- 122
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
++ E+ + N+ ++ + F+ + ++ + + L+N P F L+ L L
Sbjct 123 ---SSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLR 178
Query 513 LSNNNIANINDDMLEGLEKL----------EILD-LQHNNLARLWKHAN-----PGGPIY 556
+S + I D+ E L +L E+ D L+++ L RL N G +
Sbjct 179 ISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLS 238
Query 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVF 606
FL L LH L++N +P + DL L+++ L NN+ + + F
Sbjct 239 FLPTLRELH---LDNNKLSRVPAGL-PDLKLLQVVYLHTNNITKVGVNDF 284
>7ynz_B B Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.077, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7yo0_B B Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.077, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7ynz_F F Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.077, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7yo0_D D Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.077, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7yo0_H H Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.077, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7yo0_F F Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.077, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7ynz_H H Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.077, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7ynz_D D Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.077, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7yo3_B B Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.4 bits (93), Expect = 0.077, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>5mx0_B B Fibromodulin
Length=362
Score = 57.0 bits (136), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 94/183 (51%), Gaps = 11/183 (6%)
Query 39 HLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
H LT++P LP ++ L+L HNQ+ R+P LT+L + N I ++ + + L
Sbjct 150 HNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQEVGSSM-RGL 208
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNG 158
L +L+L +N L ++ D + L +L++ N++ + ++ F L+ + LSHN
Sbjct 209 RSLILLDLSYNHLRKVPD---GLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNS 265
Query 159 LSSTKLGTQV-QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCF 217
L++ L + +L EL LS N++Q + N++L+ L L N+I EFS F
Sbjct 266 LTNNGLASNTFNSSSLLELDLSYNQLQKIPP------VNTNLENLYLQGNRINEFSISSF 319
Query 218 HAI 220
+
Sbjct 320 CTV 322
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 45/155 (29%), Positives = 73/155 (47%), Gaps = 17/155 (11%)
Query 470 QLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGL 529
++ R F+ + L+RL L N+ P P R+L L L +N I+ + ++ LEGL
Sbjct 131 KVGRKVFSKLRHLERLYLDH---NNLTRMPGPLP--RSLRELHLDHNQISRVPNNALEGL 185
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
E L L LQHN + + ++GL L +L+L N ++P + L +L
Sbjct 186 ENLTALYLQHNEIQEVGSS---------MRGLRSLILLDLSYNHLRKVPDGLPSALEQLY 236
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
+ NN+ T+P S F L + L N +T+
Sbjct 237 MEH---NNVYTVPDSYFRGAPKLLYVRLSHNSLTN 268
Score = 42.7 bits (99), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 56/209 (27%), Positives = 90/209 (43%), Gaps = 21/209 (10%)
Query 194 FANSSLKKLELSSNQIKEFSPGCF-HAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRN 252
F S +K + +NQI G F +A G L+ N + K+ +L + +
Sbjct 88 FVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRH--LER 145
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
L L ++ L T G +L L L +N ++ V N++ L L +L++N IQ
Sbjct 146 LYLDHNNL-----TRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQE 200
Query 313 LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKS 372
+ S S+ GL RS +S L K+ D LE L ME N++ +
Sbjct 201 VGS-SMRGL---------RSLILLDLSYNHLRKVPD---GLPSALEQLYMEHNNVYTVPD 247
Query 373 NMFTGLINLKYLSLSNSFTSLRTLTNETF 401
+ F G L Y+ LS++ + L + TF
Sbjct 248 SYFRGAPKLLYVRLSHNSLTNNGLASNTF 276
Score = 40.8 bits (94), Expect = 0.055, Method: Compositional matrix adjust.
Identities = 50/206 (24%), Positives = 84/206 (41%), Gaps = 50/206 (24%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAH---------- 406
++++ ++N I I+ +F L +++L + + + + F L H
Sbjct 93 MKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNN 152
Query 407 ---------SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN 457
L L+L N+IS++ ++A L +L L L NEI QE+ G RGL +
Sbjct 153 LTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEI-QEV-GSSMRGLRS 210
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
+ + LSYN LR+V D PS + L + +NN
Sbjct 211 LILLDLSYNH-------------------LRKVP----DGLPSALEQLY------MEHNN 241
Query 518 IANINDDMLEGLEKLEILDLQHNNLA 543
+ + D G KL + L HN+L
Sbjct 242 VYTVPDSYFRGAPKLLYVRLSHNSLT 267
>2ft3_A A Biglycan
Length=332
Score = 56.6 bits (135), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 50/187 (27%), Positives = 88/187 (47%), Gaps = 11/187 (6%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI--SKLEPELCQKLP 99
L ++P +LP+++ L + N++R++P F+ + +++G N + S EP L
Sbjct 114 LVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGL- 172
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L + +L+ + L ELHL N IQ I+ ++ L L L HN +
Sbjct 173 KLNYLRISEAKLTGIPKD---LPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQI 229
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
+ G+ L L+EL L NNK+ + + D+ L+ + L +N I + F
Sbjct 230 RMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDL---KLLQVVYLHTNNITKVGVNDFCP 286
Query 220 IGRLFGL 226
+G FG+
Sbjct 287 VG--FGV 291
Score = 54.7 bits (130), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/106 (34%), Positives = 58/106 (55%), Gaps = 1/106 (1%)
Query 38 SHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
S KLT +P DLP + L+L HN+++ + + RYS+L L +G N I +E
Sbjct 180 SEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF 239
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
LP L+ L+L +N+LS++ L ++L +N+I K+ N F
Sbjct 240 LPTLRELHLDNNKLSRVP-AGLPDLKLLQVVYLHTNNITKVGVNDF 284
Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 65/264 (25%), Positives = 101/264 (38%), Gaps = 78/264 (30%)
Query 13 GLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFT 72
+ PFG C V CS L L VP ++ + T+L+L +N + L +F
Sbjct 25 AMCPFG---------CHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDF- 74
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA------------ 120
+ L L L L +N++S++ +K F+
Sbjct 75 -----------------------KGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISK 111
Query 121 ---------FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL------------ 159
++L EL + N I+K+ F +N+ +++ N L
Sbjct 112 NHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDG 171
Query 160 --------SSTKL-GTQVQL-ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
S KL G L E L EL L +NKIQA++ E D+ S L +L L NQI
Sbjct 172 LKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELE--DLLRYSKLYRLGLGHNQI 229
Query 210 KEFSPGCFHAIGRLFGLFLNNVQL 233
+ G + L L L+N +L
Sbjct 230 RMIENGSLSFLPTLRELHLDNNKL 253
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 41/157 (26%), Positives = 69/157 (44%), Gaps = 14/157 (9%)
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILD 536
A+ P LR V ++ P + + T+LDL NN+I+ + D +GL+ L L
Sbjct 25 AMCPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV 84
Query 537 LQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L +N ++++ + A L L L + N EIP + L EL+I D N
Sbjct 85 LVNNKISKIHEKA--------FSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHD---N 133
Query 597 NLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPA 633
+ +P VF+ ++ + + N +E F P
Sbjct 134 RIRKVPKGVFSGLRNMNCIEMGGN---PLENSGFEPG 167
Score = 42.4 bits (98), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 32/262 (12%)
Query 269 LGLKWT------NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
LGLK + T+LDL N+++ + D F L L L N I + + L
Sbjct 43 LGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPL- 101
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
R K IS L +I L L + DN I + +F+GL N+
Sbjct 102 --------RKLQKLYISKNHLVEIPP---NLPSSLVELRIHDNRIRKVPKGVFSGLRNMN 150
Query 383 YLSLSNSFTSLRTLTNETFVSLAHSPLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGL 440
+ + + L N F A L + L +++ K++ I D L L L
Sbjct 151 CIEMGGN-----PLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELH---LDH 202
Query 441 NEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPS 500
N+I Q + ++ ++ + L +N+ + S + +P+L+ L L L V P+
Sbjct 203 NKI-QAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRV---PA 258
Query 501 PFQPLRNLTILDLSNNNIANIN 522
L+ L ++ L NNI +
Sbjct 259 GLPDLKLLQVVYLHTNNITKVG 280
Score = 41.2 bits (95), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 62/230 (27%), Positives = 101/230 (44%), Gaps = 33/230 (14%)
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN---EIGQELTGQEW 452
L + F L H L+ L L NKISKI AFS L L+ L + N EI L
Sbjct 69 LRKDDFKGLQH--LYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLP---- 122
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
++ E+ + N+ ++ + F+ + ++ + + L+N P F L+ L L
Sbjct 123 ---SSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLR 178
Query 513 LSNNNIANINDDMLEGLEKL----------EILD-LQHNNLARLWKHAN-----PGGPIY 556
+S + I D+ E L +L E+ D L+++ L RL N G +
Sbjct 179 ISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLS 238
Query 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVF 606
FL L LH L++N +P + DL L+++ L NN+ + + F
Sbjct 239 FLPTLRELH---LDNNKLSRVPAGL-PDLKLLQVVYLHTNNITKVGVNDF 284
>2ft3_E E Biglycan
Length=332
Score = 56.6 bits (135), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 50/187 (27%), Positives = 88/187 (47%), Gaps = 11/187 (6%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI--SKLEPELCQKLP 99
L ++P +LP+++ L + N++R++P F+ + +++G N + S EP L
Sbjct 114 LVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGL- 172
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L + +L+ + L ELHL N IQ I+ ++ L L L HN +
Sbjct 173 KLNYLRISEAKLTGIPKD---LPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQI 229
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
+ G+ L L+EL L NNK+ + + D+ L+ + L +N I + F
Sbjct 230 RMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDL---KLLQVVYLHTNNITKVGVNDFCP 286
Query 220 IGRLFGL 226
+G FG+
Sbjct 287 VG--FGV 291
Score = 54.7 bits (130), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/106 (34%), Positives = 58/106 (55%), Gaps = 1/106 (1%)
Query 38 SHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
S KLT +P DLP + L+L HN+++ + + RYS+L L +G N I +E
Sbjct 180 SEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF 239
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
LP L+ L+L +N+LS++ L ++L +N+I K+ N F
Sbjct 240 LPTLRELHLDNNKLSRVP-AGLPDLKLLQVVYLHTNNITKVGVNDF 284
Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 65/264 (25%), Positives = 101/264 (38%), Gaps = 78/264 (30%)
Query 13 GLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFT 72
+ PFG C V CS L L VP ++ + T+L+L +N + L +F
Sbjct 25 AMCPFG---------CHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDF- 74
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA------------ 120
+ L L L L +N++S++ +K F+
Sbjct 75 -----------------------KGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISK 111
Query 121 ---------FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL------------ 159
++L EL + N I+K+ F +N+ +++ N L
Sbjct 112 NHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDG 171
Query 160 --------SSTKL-GTQVQL-ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
S KL G L E L EL L +NKIQA++ E D+ S L +L L NQI
Sbjct 172 LKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELE--DLLRYSKLYRLGLGHNQI 229
Query 210 KEFSPGCFHAIGRLFGLFLNNVQL 233
+ G + L L L+N +L
Sbjct 230 RMIENGSLSFLPTLRELHLDNNKL 253
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 41/157 (26%), Positives = 69/157 (44%), Gaps = 14/157 (9%)
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILD 536
A+ P LR V ++ P + + T+LDL NN+I+ + D +GL+ L L
Sbjct 25 AMCPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV 84
Query 537 LQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L +N ++++ + A L L L + N EIP + L EL+I D N
Sbjct 85 LVNNKISKIHEKA--------FSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHD---N 133
Query 597 NLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPA 633
+ +P VF+ ++ + + N +E F P
Sbjct 134 RIRKVPKGVFSGLRNMNCIEMGGN---PLENSGFEPG 167
Score = 42.4 bits (98), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 32/262 (12%)
Query 269 LGLKWT------NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
LGLK + T+LDL N+++ + D F L L L N I + + L
Sbjct 43 LGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPL- 101
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
R K IS L +I L L + DN I + +F+GL N+
Sbjct 102 --------RKLQKLYISKNHLVEIPP---NLPSSLVELRIHDNRIRKVPKGVFSGLRNMN 150
Query 383 YLSLSNSFTSLRTLTNETFVSLAHSPLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGL 440
+ + + L N F A L + L +++ K++ I D L L L
Sbjct 151 CIEMGGN-----PLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELH---LDH 202
Query 441 NEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPS 500
N+I Q + ++ ++ + L +N+ + S + +P+L+ L L L V P+
Sbjct 203 NKI-QAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRV---PA 258
Query 501 PFQPLRNLTILDLSNNNIANIN 522
L+ L ++ L NNI +
Sbjct 259 GLPDLKLLQVVYLHTNNITKVG 280
Score = 41.2 bits (95), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 62/230 (27%), Positives = 101/230 (44%), Gaps = 33/230 (14%)
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN---EIGQELTGQEW 452
L + F L H L+ L L NKISKI AFS L L+ L + N EI L
Sbjct 69 LRKDDFKGLQH--LYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLP---- 122
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
++ E+ + N+ ++ + F+ + ++ + + L+N P F L+ L L
Sbjct 123 ---SSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLR 178
Query 513 LSNNNIANINDDMLEGLEKL----------EILD-LQHNNLARLWKHAN-----PGGPIY 556
+S + I D+ E L +L E+ D L+++ L RL N G +
Sbjct 179 ISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLS 238
Query 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVF 606
FL L LH L++N +P + DL L+++ L NN+ + + F
Sbjct 239 FLPTLRELH---LDNNKLSRVPAGL-PDLKLLQVVYLHTNNITKVGVNDF 284
>2ft3_C C Biglycan
Length=332
Score = 56.6 bits (135), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 50/187 (27%), Positives = 88/187 (47%), Gaps = 11/187 (6%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI--SKLEPELCQKLP 99
L ++P +LP+++ L + N++R++P F+ + +++G N + S EP L
Sbjct 114 LVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGL- 172
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L + +L+ + L ELHL N IQ I+ ++ L L L HN +
Sbjct 173 KLNYLRISEAKLTGIPKD---LPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQI 229
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
+ G+ L L+EL L NNK+ + + D+ L+ + L +N I + F
Sbjct 230 RMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDL---KLLQVVYLHTNNITKVGVNDFCP 286
Query 220 IGRLFGL 226
+G FG+
Sbjct 287 VG--FGV 291
Score = 54.7 bits (130), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/106 (34%), Positives = 58/106 (55%), Gaps = 1/106 (1%)
Query 38 SHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
S KLT +P DLP + L+L HN+++ + + RYS+L L +G N I +E
Sbjct 180 SEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF 239
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
LP L+ L+L +N+LS++ L ++L +N+I K+ N F
Sbjct 240 LPTLRELHLDNNKLSRVP-AGLPDLKLLQVVYLHTNNITKVGVNDF 284
Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 65/264 (25%), Positives = 101/264 (38%), Gaps = 78/264 (30%)
Query 13 GLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFT 72
+ PFG C V CS L L VP ++ + T+L+L +N + L +F
Sbjct 25 AMCPFG---------CHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDF- 74
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA------------ 120
+ L L L L +N++S++ +K F+
Sbjct 75 -----------------------KGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISK 111
Query 121 ---------FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL------------ 159
++L EL + N I+K+ F +N+ +++ N L
Sbjct 112 NHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDG 171
Query 160 --------SSTKL-GTQVQL-ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
S KL G L E L EL L +NKIQA++ E D+ S L +L L NQI
Sbjct 172 LKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELE--DLLRYSKLYRLGLGHNQI 229
Query 210 KEFSPGCFHAIGRLFGLFLNNVQL 233
+ G + L L L+N +L
Sbjct 230 RMIENGSLSFLPTLRELHLDNNKL 253
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 41/157 (26%), Positives = 69/157 (44%), Gaps = 14/157 (9%)
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILD 536
A+ P LR V ++ P + + T+LDL NN+I+ + D +GL+ L L
Sbjct 25 AMCPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV 84
Query 537 LQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L +N ++++ + A L L L + N EIP + L EL+I D N
Sbjct 85 LVNNKISKIHEKA--------FSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHD---N 133
Query 597 NLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPA 633
+ +P VF+ ++ + + N +E F P
Sbjct 134 RIRKVPKGVFSGLRNMNCIEMGGN---PLENSGFEPG 167
Score = 42.4 bits (98), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 32/262 (12%)
Query 269 LGLKWT------NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
LGLK + T+LDL N+++ + D F L L L N I + + L
Sbjct 43 LGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPL- 101
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
R K IS L +I L L + DN I + +F+GL N+
Sbjct 102 --------RKLQKLYISKNHLVEIPP---NLPSSLVELRIHDNRIRKVPKGVFSGLRNMN 150
Query 383 YLSLSNSFTSLRTLTNETFVSLAHSPLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGL 440
+ + + L N F A L + L +++ K++ I D L L L
Sbjct 151 CIEMGGN-----PLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELH---LDH 202
Query 441 NEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPS 500
N+I Q + ++ ++ + L +N+ + S + +P+L+ L L L V P+
Sbjct 203 NKI-QAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRV---PA 258
Query 501 PFQPLRNLTILDLSNNNIANIN 522
L+ L ++ L NNI +
Sbjct 259 GLPDLKLLQVVYLHTNNITKVG 280
Score = 41.2 bits (95), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 62/230 (27%), Positives = 101/230 (44%), Gaps = 33/230 (14%)
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN---EIGQELTGQEW 452
L + F L H L+ L L NKISKI AFS L L+ L + N EI L
Sbjct 69 LRKDDFKGLQH--LYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLP---- 122
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
++ E+ + N+ ++ + F+ + ++ + + L+N P F L+ L L
Sbjct 123 ---SSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLR 178
Query 513 LSNNNIANINDDMLEGLEKL----------EILD-LQHNNLARLWKHAN-----PGGPIY 556
+S + I D+ E L +L E+ D L+++ L RL N G +
Sbjct 179 ISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLS 238
Query 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVF 606
FL L LH L++N +P + DL L+++ L NN+ + + F
Sbjct 239 FLPTLRELH---LDNNKLSRVPAGL-PDLKLLQVVYLHTNNITKVGVNDF 284
>2ft3_B B Biglycan
Length=332
Score = 56.6 bits (135), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 50/187 (27%), Positives = 88/187 (47%), Gaps = 11/187 (6%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI--SKLEPELCQKLP 99
L ++P +LP+++ L + N++R++P F+ + +++G N + S EP L
Sbjct 114 LVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGL- 172
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L + +L+ + L ELHL N IQ I+ ++ L L L HN +
Sbjct 173 KLNYLRISEAKLTGIPKD---LPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQI 229
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
+ G+ L L+EL L NNK+ + + D+ L+ + L +N I + F
Sbjct 230 RMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDL---KLLQVVYLHTNNITKVGVNDFCP 286
Query 220 IGRLFGL 226
+G FG+
Sbjct 287 VG--FGV 291
Score = 54.7 bits (130), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/106 (34%), Positives = 58/106 (55%), Gaps = 1/106 (1%)
Query 38 SHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
S KLT +P DLP + L+L HN+++ + + RYS+L L +G N I +E
Sbjct 180 SEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF 239
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
LP L+ L+L +N+LS++ L ++L +N+I K+ N F
Sbjct 240 LPTLRELHLDNNKLSRVP-AGLPDLKLLQVVYLHTNNITKVGVNDF 284
Score = 48.1 bits (113), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 65/264 (25%), Positives = 101/264 (38%), Gaps = 78/264 (30%)
Query 13 GLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFT 72
+ PFG C V CS L L VP ++ + T+L+L +N + L +F
Sbjct 25 AMCPFG---------CHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDF- 74
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA------------ 120
+ L L L L +N++S++ +K F+
Sbjct 75 -----------------------KGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISK 111
Query 121 ---------FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL------------ 159
++L EL + N I+K+ F +N+ +++ N L
Sbjct 112 NHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDG 171
Query 160 --------SSTKL-GTQVQL-ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
S KL G L E L EL L +NKIQA++ E D+ S L +L L NQI
Sbjct 172 LKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELE--DLLRYSKLYRLGLGHNQI 229
Query 210 KEFSPGCFHAIGRLFGLFLNNVQL 233
+ G + L L L+N +L
Sbjct 230 RMIENGSLSFLPTLRELHLDNNKL 253
Score = 44.3 bits (103), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 41/157 (26%), Positives = 69/157 (44%), Gaps = 14/157 (9%)
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILD 536
A+ P LR V ++ P + + T+LDL NN+I+ + D +GL+ L L
Sbjct 25 AMCPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV 84
Query 537 LQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L +N ++++ + A L L L + N EIP + L EL+I D N
Sbjct 85 LVNNKISKIHEKA--------FSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHD---N 133
Query 597 NLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPA 633
+ +P VF+ ++ + + N +E F P
Sbjct 134 RIRKVPKGVFSGLRNMNCIEMGGN---PLENSGFEPG 167
Score = 42.4 bits (98), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 32/262 (12%)
Query 269 LGLKWT------NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
LGLK + T+LDL N+++ + D F L L L N I + + L
Sbjct 43 LGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPL- 101
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
R K IS L +I L L + DN I + +F+GL N+
Sbjct 102 --------RKLQKLYISKNHLVEIPP---NLPSSLVELRIHDNRIRKVPKGVFSGLRNMN 150
Query 383 YLSLSNSFTSLRTLTNETFVSLAHSPLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGL 440
+ + + L N F A L + L +++ K++ I D L L L
Sbjct 151 CIEMGGN-----PLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELH---LDH 202
Query 441 NEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPS 500
N+I Q + ++ ++ + L +N+ + S + +P+L+ L L L V P+
Sbjct 203 NKI-QAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRV---PA 258
Query 501 PFQPLRNLTILDLSNNNIANIN 522
L+ L ++ L NNI +
Sbjct 259 GLPDLKLLQVVYLHTNNITKVG 280
Score = 41.2 bits (95), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 62/230 (27%), Positives = 101/230 (44%), Gaps = 33/230 (14%)
Query 396 LTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN---EIGQELTGQEW 452
L + F L H L+ L L NKISKI AFS L L+ L + N EI L
Sbjct 69 LRKDDFKGLQH--LYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLP---- 122
Query 453 RGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
++ E+ + N+ ++ + F+ + ++ + + L+N P F L+ L L
Sbjct 123 ---SSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLR 178
Query 513 LSNNNIANINDDMLEGLEKL----------EILD-LQHNNLARLWKHAN-----PGGPIY 556
+S + I D+ E L +L E+ D L+++ L RL N G +
Sbjct 179 ISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLS 238
Query 557 FLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVF 606
FL L LH L++N +P + DL L+++ L NN+ + + F
Sbjct 239 FLPTLRELH---LDNNKLSRVPAGL-PDLKLLQVVYLHTNNITKVGVNDF 284
>7yo1_B B Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.0 bits (92), Expect = 0.086, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7yo1_F F Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.0 bits (92), Expect = 0.086, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7yo1_H H Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.0 bits (92), Expect = 0.086, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>7yo1_D D Leucine-rich repeat-containing protein 26
Length=334
Score = 56.6 bits (135), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 48/156 (31%), Positives = 68/156 (44%), Gaps = 1/156 (1%)
Query 28 CT-VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
CT V +A CS L L VP L + L L HN++R LP F L LD+ N
Sbjct 47 CTCVPGGLASCSALSLPAVPPGLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENG 106
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
+ + L L++L+L N+L L+ TFA L L L N + +++
Sbjct 107 LHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALRNLSLAGNRLARLEPAALGAL 166
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNK 182
L +L L N L++ G +L L L L N
Sbjct 167 PLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNP 202
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 32/122 (26%), Positives = 47/122 (39%), Gaps = 23/122 (19%)
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLK 613
P G L L+L NG + V F L L+++DL N L L F +L+
Sbjct 87 PPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRALR 146
Query 614 SLNLQKNLITSVEKKVFG--PAFRNLT---------------------ELDMRFNPFDCT 650
+L+L N + +E G P R+L+ L +R NP+ C
Sbjct 147 NLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCG 206
Query 651 CE 652
C
Sbjct 207 CA 208
Score = 40.0 bits (92), Expect = 0.086, Method: Compositional matrix adjust.
Identities = 34/113 (30%), Positives = 49/113 (43%), Gaps = 7/113 (6%)
Query 133 NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELD 192
N ++ + F L LDL NGL S + L LQ L LS N+++AL
Sbjct 81 NRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAP---G 137
Query 193 IFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN---VQLGPSLTEKL 241
FA +L+ L L+ N++ P A+ L L L + L P L +L
Sbjct 138 TFAPLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAALAPGLLGRL 190
Score = 39.7 bits (91), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 50/130 (38%), Gaps = 30/130 (23%)
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDS----------------------SPSPF 502
+N+ L +FA +LQRL LR L +V +P F
Sbjct 80 HNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTF 139
Query 503 QPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PLR L L L+ N +A + L L L L LQ N LA L PG L L
Sbjct 140 APLRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNELAAL----APG----LLGRLP 191
Query 563 HLHILNLESN 572
L L+L N
Sbjct 192 ALDALHLRGN 201
>2ft3_F F Biglycan
Length=332
Score = 56.6 bits (135), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 50/187 (27%), Positives = 88/187 (47%), Gaps = 11/187 (6%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI--SKLEPELCQKLP 99
L ++P +LP+++ L + N++R++P F+ + +++G N + S EP L
Sbjct 114 LVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGL- 172
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L + +L+ + L ELHL N IQ I+ ++ L L L HN +
Sbjct 173 KLNYLRISEAKLTGIPKD---LPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQI 229
Query 160 SSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHA 219
+ G+ L L+EL L NNK+ + + D+ L+ + L +N I + F
Sbjct 230 RMIENGSLSFLPTLRELHLDNNKLSRVPAGLPDL---KLLQVVYLHTNNITKVGVNDFCP 286
Query 220 IGRLFGL 226
+G FG+
Sbjct 287 VG--FGV 291
Score = 54.7 bits (130), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 36/106 (34%), Positives = 58/106 (55%), Gaps = 1/106 (1%)
Query 38 SHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQK 97
S KLT +P DLP + L+L HN+++ + + RYS+L L +G N I +E
Sbjct 180 SEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF 239
Query 98 LPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
LP L+ L+L +N+LS++ L ++L +N+I K+ N F
Sbjct 240 LPTLRELHLDNNKLSRVP-AGLPDLKLLQVVYLHTNNITKVGVNDF 284
Score = 47.8 bits (112), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 65/264 (25%), Positives = 101/264 (38%), Gaps = 78/264 (30%)
Query 13 GLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFT 72
+ PFG C V CS L L VP ++ + T+L+L +N + L +F
Sbjct 25 AMCPFG---------CHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDF- 74
Query 73 RYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFA------------ 120
+ L L L L +N++S++ +K F+
Sbjct 75 -----------------------KGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISK 111
Query 121 ---------FCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL------------ 159
++L EL + N I+K+ F +N+ +++ N L
Sbjct 112 NHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDG 171
Query 160 --------SSTKL-GTQVQL-ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
S KL G L E L EL L +NKIQA++ E D+ S L +L L NQI
Sbjct 172 LKLNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELE--DLLRYSKLYRLGLGHNQI 229
Query 210 KEFSPGCFHAIGRLFGLFLNNVQL 233
+ G + L L L+N +L
Sbjct 230 RMIENGSLSFLPTLRELHLDNNKL 253
Score = 43.9 bits (102), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 41/157 (26%), Positives = 69/157 (44%), Gaps = 14/157 (9%)
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILD 536
A+ P LR V ++ P + + T+LDL NN+I+ + D +GL+ L L
Sbjct 25 AMCPFGCHCHLRVVQCSDLGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV 84
Query 537 LQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLN 596
L +N ++++ + A L L L + N EIP + L EL+I D N
Sbjct 85 LVNNKISKIHEKA--------FSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHD---N 133
Query 597 NLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPA 633
+ +P VF+ ++ + + N +E F P
Sbjct 134 RIRKVPKGVFSGLRNMNCIEMGGN---PLENSGFEPG 167
Score = 42.4 bits (98), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 63/262 (24%), Positives = 105/262 (40%), Gaps = 32/262 (12%)
Query 269 LGLKWT------NLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
LGLK + T+LDL N+++ + D F L L L N I + + L
Sbjct 43 LGLKAVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPL- 101
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
R K IS L +I L L + DN I + +F+GL N+
Sbjct 102 --------RKLQKLYISKNHLVEIPP---NLPSSLVELRIHDNRIRKVPKGVFSGLRNMN 150
Query 383 YLSLSNSFTSLRTLTNETFVSLAHSPLHI--LNLTKNKISKIESDAFSWLGHLEVLDLGL 440
+ + + L N F A L + L +++ K++ I D L L L
Sbjct 151 CIEMGGN-----PLENSGFEPGAFDGLKLNYLRISEAKLTGIPKDLPETLNELH---LDH 202
Query 441 NEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPS 500
N+I Q + ++ ++ + L +N+ + S + +P+L+ L L L V P+
Sbjct 203 NKI-QAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLSRV---PA 258
Query 501 PFQPLRNLTILDLSNNNIANIN 522
L+ L ++ L NNI +
Sbjct 259 GLPDLKLLQVVYLHTNNITKVG 280
Score = 41.2 bits (95), Expect = 0.037, Method: Compositional matrix adjust.
Identities = 64/239 (27%), Positives = 105/239 (44%), Gaps = 36/239 (15%)
Query 387 SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN---EI 443
+N + LR + F L H L+ L L NKISKI AFS L L+ L + N EI
Sbjct 63 NNDISELRK---DDFKGLQH--LYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHLVEI 117
Query 444 GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ 503
L ++ E+ + N+ ++ + F+ + ++ + + L+N P F
Sbjct 118 PPNLP-------SSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFD 170
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKL----------EILD-LQHNNLARLWKHAN-- 550
L+ L L +S + I D+ E L +L E+ D L+++ L RL N
Sbjct 171 GLK-LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQI 229
Query 551 ---PGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVF 606
G + FL L LH L++N +P + DL L+++ L NN+ + + F
Sbjct 230 RMIENGSLSFLPTLRELH---LDNNKLSRVPAGL-PDLKLLQVVYLHTNNITKVGVNDF 284
>5yq5_D D Osteomodulin
Length=430
Score = 57.0 bits (136), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 56/201 (28%), Positives = 98/201 (49%), Gaps = 13/201 (6%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS--KLEPEL 94
C + KL +P+ +P +I L L N++ + A +F + L +++ N I K++ +
Sbjct 76 CDNRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGV 134
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
KLP L L+L+HN L + F +L L L N I K++ N NL LDL
Sbjct 135 FAKLPNLLQLHLEHNNLEEFP---FPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDL 191
Query 155 SHNGLSSTKLGTQV--QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
+N L + L ++ ++E L +L L +N+++++ SSL L L +N I
Sbjct 192 CYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPG-----LPSSLMYLSLENNSISSI 246
Query 213 SPGCFHAIGRLFGLFLNNVQL 233
F + +L L +++ +L
Sbjct 247 PEKYFDKLPKLHTLRMSHNKL 267
Score = 53.5 bits (127), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 63/204 (31%), Positives = 99/204 (49%), Gaps = 20/204 (10%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L+L HN L P F L L +G+N ISKL+ L L +L+L +N L
Sbjct 140 NLLQLHLEHNNLEEFP---FPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYL 196
Query 112 --SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
S L DK FA L +L+L SN ++ + P +L+ L L +N +SS +
Sbjct 197 HDSLLKDKIFAKMEKLMQLNLCSNRLESM---PPGLPSSLMYLSLENNSISSIPEKYFDK 253
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L L L +S+NK+Q + +IF ++ +L + N++K+ F+ L L+L
Sbjct 254 LPKLHTLRMSHNKLQDIP---YNIFNLPNIVELSVGHNKLKQ----AFYIPRNLEHLYLQ 306
Query 230 NVQLGPSLTEKLCLELANTSIRNL 253
N ++ EK+ L + SI L
Sbjct 307 NNEI-----EKMNLTVMCPSIDPL 325
Score = 47.0 bits (110), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 59/238 (25%), Positives = 107/238 (45%), Gaps = 27/238 (11%)
Query 299 QLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK-QSIS---LASLPKI-------- 346
++ +L++N I+ + ++S +++ +NL + K Q I A LP +
Sbjct 90 HIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHN 149
Query 347 --DDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
++F F K LE L + N+I +++N GL+NL L L ++ L ++ F +
Sbjct 150 NLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKM 209
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS 464
L LNL N++ + S L +L + + ++ I ++ + L + + +S
Sbjct 210 EK--LMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKY----FDKLPKLHTLRMS 263
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
+NK + N F L P++ L + LK P RNL L L NN I +N
Sbjct 264 HNKLQDIPYNIFNL-PNIVELSVGHNKLKQAFYIP------RNLEHLYLQNNEIEKMN 314
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 62/246 (25%), Positives = 116/246 (47%), Gaps = 29/246 (12%)
Query 125 LTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL--GTQVQLENLQELLLSNNK 182
+ +L+L N I+ + N F+ +L ++LSHN + S K+ G +L NL +L L +N
Sbjct 91 IQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNN 150
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPS-LTEKL 241
+ EE SL++L L N+I + + L L L L S L +K+
Sbjct 151 L-----EEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKI 205
Query 242 CLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
++ + L+L +++L + GL ++L L L N+++ + F LP+L
Sbjct 206 FAKME--KLMQLNLCSNRLESMPP----GLP-SSLMYLSLENNSISSIPEKYFDKLPKLH 258
Query 302 YFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLN 361
+ +N +Q + +++ L N+ L++ + KQ +F + LEHL
Sbjct 259 TLRMSHNKLQDI-PYNIFNLPNIVELSVGHNKLKQ-------------AFYIPRNLEHLY 304
Query 362 MEDNDI 367
+++N+I
Sbjct 305 LQNNEI 310
Score = 42.0 bits (97), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 47/175 (27%), Positives = 86/175 (49%), Gaps = 16/175 (9%)
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
I ++YL +N+ +T NSF L+ + L +K+ F L NL L L +NN
Sbjct 91 IQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNN 150
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDE- 576
+ + + LE+L L +N +++L +A + GL +L +L+L N +
Sbjct 151 LEEFPFPLPKSLERLL---LGYNEISKLQTNA--------MDGLVNLTMLDLCYNYLHDS 199
Query 577 -IPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+ ++F + +L ++L N L ++P + SL L+L+ N I+S+ +K F
Sbjct 200 LLKDKIFAKMEKLMQLNLCSNRLESMPPGL---PSSLMYLSLENNSISSIPEKYF 251
>5yq5_A A Osteomodulin
Length=430
Score = 57.0 bits (136), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 56/201 (28%), Positives = 98/201 (49%), Gaps = 13/201 (6%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI--SKLEPEL 94
C + KL +P+ +P +I L L N++ + A +F + L +++ N I K++ +
Sbjct 76 CDNRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGV 134
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
KLP L L+L+HN L + F +L L L N I K++ N NL LDL
Sbjct 135 FAKLPNLLQLHLEHNNLEEFP---FPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDL 191
Query 155 SHNGLSSTKLGTQV--QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
+N L + L ++ ++E L +L L +N+++++ SSL L L +N I
Sbjct 192 CYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPG-----LPSSLMYLSLENNSISSI 246
Query 213 SPGCFHAIGRLFGLFLNNVQL 233
F + +L L +++ +L
Sbjct 247 PEKYFDKLPKLHTLRMSHNKL 267
Score = 53.5 bits (127), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 63/204 (31%), Positives = 99/204 (49%), Gaps = 20/204 (10%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L+L HN L P F L L +G+N ISKL+ L L +L+L +N L
Sbjct 140 NLLQLHLEHNNLEEFP---FPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYL 196
Query 112 --SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
S L DK FA L +L+L SN ++ + P +L+ L L +N +SS +
Sbjct 197 HDSLLKDKIFAKMEKLMQLNLCSNRLESM---PPGLPSSLMYLSLENNSISSIPEKYFDK 253
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L L L +S+NK+Q + +IF ++ +L + N++K+ F+ L L+L
Sbjct 254 LPKLHTLRMSHNKLQDIP---YNIFNLPNIVELSVGHNKLKQ----AFYIPRNLEHLYLQ 306
Query 230 NVQLGPSLTEKLCLELANTSIRNL 253
N ++ EK+ L + SI L
Sbjct 307 NNEI-----EKMNLTVMCPSIDPL 325
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 59/238 (25%), Positives = 107/238 (45%), Gaps = 27/238 (11%)
Query 299 QLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK-QSIS---LASLPKI-------- 346
++ +L++N I+ + ++S +++ +NL + K Q I A LP +
Sbjct 90 HIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHN 149
Query 347 --DDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
++F F K LE L + N+I +++N GL+NL L L ++ L ++ F +
Sbjct 150 NLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKM 209
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS 464
L LNL N++ + S L +L + + ++ I ++ + L + + +S
Sbjct 210 EK--LMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKY----FDKLPKLHTLRMS 263
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
+NK + N F L P++ L + LK P RNL L L NN I +N
Sbjct 264 HNKLQDIPYNIFNL-PNIVELSVGHNKLKQAFYIP------RNLEHLYLQNNEIEKMN 314
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 62/246 (25%), Positives = 116/246 (47%), Gaps = 29/246 (12%)
Query 125 LTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL--GTQVQLENLQELLLSNNK 182
+ +L+L N I+ + N F+ +L ++LSHN + S K+ G +L NL +L L +N
Sbjct 91 IQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNN 150
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPS-LTEKL 241
+ EE SL++L L N+I + + L L L L S L +K+
Sbjct 151 L-----EEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKI 205
Query 242 CLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
++ + L+L +++L + GL ++L L L N+++ + F LP+L
Sbjct 206 FAKME--KLMQLNLCSNRLESMPP----GLP-SSLMYLSLENNSISSIPEKYFDKLPKLH 258
Query 302 YFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLN 361
+ +N +Q + +++ L N+ L++ + KQ +F + LEHL
Sbjct 259 TLRMSHNKLQDI-PYNIFNLPNIVELSVGHNKLKQ-------------AFYIPRNLEHLY 304
Query 362 MEDNDI 367
+++N+I
Sbjct 305 LQNNEI 310
Score = 41.6 bits (96), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 47/175 (27%), Positives = 86/175 (49%), Gaps = 16/175 (9%)
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
I ++YL +N+ +T NSF L+ + L +K+ F L NL L L +NN
Sbjct 91 IQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNN 150
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDE- 576
+ + + LE+L L +N +++L +A + GL +L +L+L N +
Sbjct 151 LEEFPFPLPKSLERLL---LGYNEISKLQTNA--------MDGLVNLTMLDLCYNYLHDS 199
Query 577 -IPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+ ++F + +L ++L N L ++P + SL L+L+ N I+S+ +K F
Sbjct 200 LLKDKIFAKMEKLMQLNLCSNRLESMPPGL---PSSLMYLSLENNSISSIPEKYF 251
>4j0m_B B Serine/threonine-protein kinase BRI1-like 1
Length=740
Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 136/567 (24%), Positives = 228/567 (40%), Gaps = 93/567 (16%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE-LCQKLPM-LKVLNLQH 108
+N+ +N+++N+L + LT++D+ +N +S PE P LK L+L H
Sbjct 127 SNLVSVNISNNKLVGKLGFAPSSLQSLTTVDLSYNILSDKIPESFISDFPASLKYLDLTH 186
Query 109 NELS-QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV--KQKNLITLDLSHNGLSSTKLG 165
N LS SD +F C NLT L N++ K P K L TL++S N L+
Sbjct 187 NNLSGDFSDLSFGICGNLTFFSLSQNNLSGDKF-PITLPNCKFLETLNISRNNLAGKIPN 245
Query 166 TQV--QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
+ +NL++L L++N++ EL + +L L+LS N P F A
Sbjct 246 GEYWGSFQNLKQLSLAHNRLSGEIPPELSLLC-KTLVILDLSGNTFSGELPSQFTAC--- 301
Query 224 FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL-KWTNLTMLDLS 282
++L N+ LG + L + I ++ + S + + L +NL +LDLS
Sbjct 302 --VWLQNLNLGNNYLSGDFLNTVVSKITGITYLYVAYNNISGSVPISLTNCSNLRVLDLS 359
Query 283 YNNLNVVGNDSFAWL---PQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS 339
N F L P LE + N + L +++ ++L SF + +
Sbjct 360 SNGFTGNVPSGFCSLQSSPVLEKILIANNYLSGTVPMELGKCKSLKTIDL--SFNELT-- 415
Query 340 LASLPKIDDFSFQWLKCLEHLNMEDNDIPG-IKSNMFTGLINLKYLSLSNSF------TS 392
+PK L L L M N++ G I + NL+ L L+N+ S
Sbjct 416 -GPIPK----EIWMLPNLSDLVMWANNLTGTIPEGVCVKGGNLETLILNNNLLTGSIPES 470
Query 393 LRTLTNETFVSLAHS------PLHILNLTKNKISKIESDAFSW-----LGHLEVL---DL 438
+ TN ++SL+ + P I NL+K I ++ +++ S LG+ + L DL
Sbjct 471 ISRCTNMIWISLSSNRLTGKIPSGIGNLSKLAILQLGNNSLSGNVPRQLGNCKSLIWLDL 530
Query 439 GLNEIGQELTGQ---------------------------EWRGLENIFEI---------- 461
N + +L G+ + RG + E
Sbjct 531 NSNNLTGDLPGELASQAGLVMPGSVSGKQFAFVRNEGGTDCRGAGGLVEFEGIRAERLER 590
Query 462 ------YLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
+ Y +T +F+ S+ + A+ P + + L +L+L +
Sbjct 591 LPMVHSCPATRIYSGMTMYTFSANGSMIYFDISYNAVSGF--IPPGYGNMGYLQVLNLGH 648
Query 516 NNIANINDDMLEGLEKLEILDLQHNNL 542
N I D GL+ + +LDL HNNL
Sbjct 649 NRITGTIPDSFGGLKAIGVLDLSHNNL 675
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 122/544 (22%), Positives = 205/544 (38%), Gaps = 83/544 (15%)
Query 52 NITVLNLTHNQLR-RLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
N+ L+L HN+L +P L LD+ NT S P L+ LNL +N
Sbjct 254 NLKQLSLAHNRLSGEIPPELSLLCKTLVILDLSGNTFSGELPSQFTACVWLQNLNLGNNY 313
Query 111 LS-QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
LS + + T +T L++ N+I NL LDLS NG +
Sbjct 314 LSGDFLNTVVSKITGITYLYVAYNNISGSVPISLTNCSNLRVLDLSSNGFTGNVPSGFCS 373
Query 170 LEN---LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGL 226
L++ L+++L++NN + EL SLK ++LS N++ P + L L
Sbjct 374 LQSSPVLEKILIANNYLSGTVPMELG--KCKSLKTIDLSFNELTGPIPKEIWMLPNLSDL 431
Query 227 FLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL 286
+ L ++ E +C++ N + L L+N+ L+ + + + TN+ + LS N L
Sbjct 432 VMWANNLTGTIPEGVCVKGGN--LETLILNNNLLTGSIPESIS--RCTNMIWISLSSNRL 487
Query 287 NVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL-----NLKRSFTKQSISLA 341
L +L L N++ L ++ +L NL + S A
Sbjct 488 TGKIPSGIGNLSKLAILQLGNNSLSGNVPRQLGNCKSLIWLDLNSNNLTGDLPGELASQA 547
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM-FTGLI--NLKYLSLSNSFTSLRTLTN 398
L S + + N D G + F G+ L+ L + +S + R +
Sbjct 548 GLVMPGSVSGKQFAFVR--NEGGTDCRGAGGLVEFEGIRAERLERLPMVHSCPATRIYSG 605
Query 399 ETFVSL-AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN 457
T + A+ + +++ N +S + +G+L+VL+LG N I
Sbjct 606 MTMYTFSANGSMIYFDISYNAVSGFIPPGYGNMGYLQVLNLGHNRI-------------- 651
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
+ P F L+ + +LDLS+NN
Sbjct 652 -------------------------------------TGTIPDSFGGLKAIGVLDLSHNN 674
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESN-GFDE 576
+ L L L LD+ +NNL GPI F L+ + +N G
Sbjct 675 LQGYLPGSLGSLSFLSDLDVSNNNLT---------GPIPFGGQLTTFPVSRYANNSGLCG 725
Query 577 IPVE 580
+P+
Sbjct 726 VPLR 729
Score = 39.7 bits (91), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 118/459 (26%), Positives = 187/459 (41%), Gaps = 34/459 (7%)
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIKNNPFVKQKNLITLDL 154
LP L+ L LQ N S D + + C L L L SNSI + + F K NL+++++
Sbjct 76 ALPNLQNLYLQGNYFSSGGDSSGSDCY-LQVLDLSSNSISDYSMVDYVFSKCSNLVSVNI 134
Query 155 SHNGLSSTKLG-TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK-EF 212
S+N L KLG L++L + LS N + E +SLK L+L+ N + +F
Sbjct 135 SNNKLVG-KLGFAPSSLQSLTTVDLSYNILSDKIPESFISDFPASLKYLDLTHNNLSGDF 193
Query 213 SPGCFHAIGRL--FGLFLNNVQLGPSLTEKLCLELANTS-IRNLSLSNSQLST-TSNTTF 268
S F G L F L NN+ +K + L N + L++S + L+ N +
Sbjct 194 SDLSFGICGNLTFFSLSQNNLS-----GDKFPITLPNCKFLETLNISRNNLAGKIPNGEY 248
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQ-LEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
G + NL L L++N L+ + L + L L N ++ L
Sbjct 249 WG-SFQNLKQLSLAHNRLSGEIPPELSLLCKTLVILDLSGNTFSGELPSQFTACVWLQNL 307
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
NL ++ + KI ++ ++ N+I G T NL+ L LS
Sbjct 308 NLGNNYLSGDFLNTVVSKITGITYLYVAY--------NNISGSVPISLTNCSNLRVLDLS 359
Query 388 -NSFTSLRTLTNETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
N FT F SL SP L + + N +S L+ +DL NE+
Sbjct 360 SNGFTGN---VPSGFCSLQSSPVLEKILIANNYLSGTVPMELGKCKSLKTIDLSFNELTG 416
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS-LQRLMLRRVALKNVDSSPSPFQP 504
+ + W L N+ ++ + N + L+ L+L L S P
Sbjct 417 PIPKEIWM-LPNLSDLVMWANNLTGTIPEGVCVKGGNLETLILNNNLL--TGSIPESISR 473
Query 505 LRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
N+ + LS+N + + L KL IL L +N+L+
Sbjct 474 CTNMIWISLSSNRLTGKIPSGIGNLSKLAILQLGNNSLS 512
Score = 34.7 bits (78), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 67/221 (30%), Positives = 97/221 (44%), Gaps = 12/221 (5%)
Query 409 LHILNLTKNKIS--KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYN 466
L +L+L+ N IS + FS +L +++ N++ +L G L+++ + LSYN
Sbjct 103 LQVLDLSSNSISDYSMVDYVFSKCSNLVSVNISNNKLVGKL-GFAPSSLQSLTTVDLSYN 161
Query 467 KYLQLTRNSFA--LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDD 524
SF SL+ L L L D S F NLT LS NN++
Sbjct 162 ILSDKIPESFISDFPASLKYLDLTHNNLSG-DFSDLSFGICGNLTFFSLSQNNLSGDKFP 220
Query 525 M-LEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFK 583
+ L + LE L++ NNLA + G LK LS H N S EIP E+
Sbjct 221 ITLPNCKFLETLNISRNNLAGKIPNGEYWGSFQNLKQLSLAH--NRLS---GEIPPELSL 275
Query 584 DLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
L I+DL N + S F V L++LNL N ++
Sbjct 276 LCKTLVILDLSGNTFSGELPSQFTACVWLQNLNLGNNYLSG 316
>4j0m_A A Serine/threonine-protein kinase BRI1-like 1
Length=740
Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 136/567 (24%), Positives = 228/567 (40%), Gaps = 93/567 (16%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE-LCQKLPM-LKVLNLQH 108
+N+ +N+++N+L + LT++D+ +N +S PE P LK L+L H
Sbjct 127 SNLVSVNISNNKLVGKLGFAPSSLQSLTTVDLSYNILSDKIPESFISDFPASLKYLDLTH 186
Query 109 NELS-QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFV--KQKNLITLDLSHNGLSSTKLG 165
N LS SD +F C NLT L N++ K P K L TL++S N L+
Sbjct 187 NNLSGDFSDLSFGICGNLTFFSLSQNNLSGDKF-PITLPNCKFLETLNISRNNLAGKIPN 245
Query 166 TQV--QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRL 223
+ +NL++L L++N++ EL + +L L+LS N P F A
Sbjct 246 GEYWGSFQNLKQLSLAHNRLSGEIPPELSLLC-KTLVILDLSGNTFSGELPSQFTAC--- 301
Query 224 FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGL-KWTNLTMLDLS 282
++L N+ LG + L + I ++ + S + + L +NL +LDLS
Sbjct 302 --VWLQNLNLGNNYLSGDFLNTVVSKITGITYLYVAYNNISGSVPISLTNCSNLRVLDLS 359
Query 283 YNNLNVVGNDSFAWL---PQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSIS 339
N F L P LE + N + L +++ ++L SF + +
Sbjct 360 SNGFTGNVPSGFCSLQSSPVLEKILIANNYLSGTVPMELGKCKSLKTIDL--SFNELT-- 415
Query 340 LASLPKIDDFSFQWLKCLEHLNMEDNDIPG-IKSNMFTGLINLKYLSLSNSF------TS 392
+PK L L L M N++ G I + NL+ L L+N+ S
Sbjct 416 -GPIPK----EIWMLPNLSDLVMWANNLTGTIPEGVCVKGGNLETLILNNNLLTGSIPES 470
Query 393 LRTLTNETFVSLAHS------PLHILNLTKNKISKIESDAFSW-----LGHLEVL---DL 438
+ TN ++SL+ + P I NL+K I ++ +++ S LG+ + L DL
Sbjct 471 ISRCTNMIWISLSSNRLTGKIPSGIGNLSKLAILQLGNNSLSGNVPRQLGNCKSLIWLDL 530
Query 439 GLNEIGQELTGQ---------------------------EWRGLENIFEI---------- 461
N + +L G+ + RG + E
Sbjct 531 NSNNLTGDLPGELASQAGLVMPGSVSGKQFAFVRNEGGTDCRGAGGLVEFEGIRAERLER 590
Query 462 ------YLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
+ Y +T +F+ S+ + A+ P + + L +L+L +
Sbjct 591 LPMVHSCPATRIYSGMTMYTFSANGSMIYFDISYNAVSGF--IPPGYGNMGYLQVLNLGH 648
Query 516 NNIANINDDMLEGLEKLEILDLQHNNL 542
N I D GL+ + +LDL HNNL
Sbjct 649 NRITGTIPDSFGGLKAIGVLDLSHNNL 675
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 122/544 (22%), Positives = 205/544 (38%), Gaps = 83/544 (15%)
Query 52 NITVLNLTHNQLR-RLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
N+ L+L HN+L +P L LD+ NT S P L+ LNL +N
Sbjct 254 NLKQLSLAHNRLSGEIPPELSLLCKTLVILDLSGNTFSGELPSQFTACVWLQNLNLGNNY 313
Query 111 LS-QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
LS + + T +T L++ N+I NL LDLS NG +
Sbjct 314 LSGDFLNTVVSKITGITYLYVAYNNISGSVPISLTNCSNLRVLDLSSNGFTGNVPSGFCS 373
Query 170 LEN---LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGL 226
L++ L+++L++NN + EL SLK ++LS N++ P + L L
Sbjct 374 LQSSPVLEKILIANNYLSGTVPMELG--KCKSLKTIDLSFNELTGPIPKEIWMLPNLSDL 431
Query 227 FLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNL 286
+ L ++ E +C++ N + L L+N+ L+ + + + TN+ + LS N L
Sbjct 432 VMWANNLTGTIPEGVCVKGGN--LETLILNNNLLTGSIPESIS--RCTNMIWISLSSNRL 487
Query 287 NVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL-----NLKRSFTKQSISLA 341
L +L L N++ L ++ +L NL + S A
Sbjct 488 TGKIPSGIGNLSKLAILQLGNNSLSGNVPRQLGNCKSLIWLDLNSNNLTGDLPGELASQA 547
Query 342 SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM-FTGLI--NLKYLSLSNSFTSLRTLTN 398
L S + + N D G + F G+ L+ L + +S + R +
Sbjct 548 GLVMPGSVSGKQFAFVR--NEGGTDCRGAGGLVEFEGIRAERLERLPMVHSCPATRIYSG 605
Query 399 ETFVSL-AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN 457
T + A+ + +++ N +S + +G+L+VL+LG N I
Sbjct 606 MTMYTFSANGSMIYFDISYNAVSGFIPPGYGNMGYLQVLNLGHNRI-------------- 651
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
+ P F L+ + +LDLS+NN
Sbjct 652 -------------------------------------TGTIPDSFGGLKAIGVLDLSHNN 674
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESN-GFDE 576
+ L L L LD+ +NNL GPI F L+ + +N G
Sbjct 675 LQGYLPGSLGSLSFLSDLDVSNNNLT---------GPIPFGGQLTTFPVSRYANNSGLCG 725
Query 577 IPVE 580
+P+
Sbjct 726 VPLR 729
Score = 39.7 bits (91), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 118/459 (26%), Positives = 187/459 (41%), Gaps = 34/459 (7%)
Query 97 KLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIKNNPFVKQKNLITLDL 154
LP L+ L LQ N S D + + C L L L SNSI + + F K NL+++++
Sbjct 76 ALPNLQNLYLQGNYFSSGGDSSGSDCY-LQVLDLSSNSISDYSMVDYVFSKCSNLVSVNI 134
Query 155 SHNGLSSTKLG-TQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK-EF 212
S+N L KLG L++L + LS N + E +SLK L+L+ N + +F
Sbjct 135 SNNKLVG-KLGFAPSSLQSLTTVDLSYNILSDKIPESFISDFPASLKYLDLTHNNLSGDF 193
Query 213 SPGCFHAIGRL--FGLFLNNVQLGPSLTEKLCLELANTS-IRNLSLSNSQLST-TSNTTF 268
S F G L F L NN+ +K + L N + L++S + L+ N +
Sbjct 194 SDLSFGICGNLTFFSLSQNNLS-----GDKFPITLPNCKFLETLNISRNNLAGKIPNGEY 248
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQ-LEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
G + NL L L++N L+ + L + L L N ++ L
Sbjct 249 WG-SFQNLKQLSLAHNRLSGEIPPELSLLCKTLVILDLSGNTFSGELPSQFTACVWLQNL 307
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
NL ++ + KI ++ ++ N+I G T NL+ L LS
Sbjct 308 NLGNNYLSGDFLNTVVSKITGITYLYVAY--------NNISGSVPISLTNCSNLRVLDLS 359
Query 388 -NSFTSLRTLTNETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQ 445
N FT F SL SP L + + N +S L+ +DL NE+
Sbjct 360 SNGFTGN---VPSGFCSLQSSPVLEKILIANNYLSGTVPMELGKCKSLKTIDLSFNELTG 416
Query 446 ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPS-LQRLMLRRVALKNVDSSPSPFQP 504
+ + W L N+ ++ + N + L+ L+L L S P
Sbjct 417 PIPKEIWM-LPNLSDLVMWANNLTGTIPEGVCVKGGNLETLILNNNLL--TGSIPESISR 473
Query 505 LRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
N+ + LS+N + + L KL IL L +N+L+
Sbjct 474 CTNMIWISLSSNRLTGKIPSGIGNLSKLAILQLGNNSLS 512
Score = 34.7 bits (78), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 67/221 (30%), Positives = 97/221 (44%), Gaps = 12/221 (5%)
Query 409 LHILNLTKNKIS--KIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYN 466
L +L+L+ N IS + FS +L +++ N++ +L G L+++ + LSYN
Sbjct 103 LQVLDLSSNSISDYSMVDYVFSKCSNLVSVNISNNKLVGKL-GFAPSSLQSLTTVDLSYN 161
Query 467 KYLQLTRNSFA--LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDD 524
SF SL+ L L L D S F NLT LS NN++
Sbjct 162 ILSDKIPESFISDFPASLKYLDLTHNNLSG-DFSDLSFGICGNLTFFSLSQNNLSGDKFP 220
Query 525 M-LEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFK 583
+ L + LE L++ NNLA + G LK LS H N S EIP E+
Sbjct 221 ITLPNCKFLETLNISRNNLAGKIPNGEYWGSFQNLKQLSLAH--NRLS---GEIPPELSL 275
Query 584 DLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS 624
L I+DL N + S F V L++LNL N ++
Sbjct 276 LCKTLVILDLSGNTFSGELPSQFTACVWLQNLNLGNNYLSG 316
>5yq5_C C Osteomodulin
Length=430
Score = 57.0 bits (136), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 56/201 (28%), Positives = 98/201 (49%), Gaps = 13/201 (6%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI--SKLEPEL 94
C + KL +P+ +P +I L L N++ + A +F + L +++ N I K++ +
Sbjct 76 CDNRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGV 134
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
KLP L L+L+HN L + F +L L L N I K++ N NL LDL
Sbjct 135 FAKLPNLLQLHLEHNNLEEFP---FPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDL 191
Query 155 SHNGLSSTKLGTQV--QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
+N L + L ++ ++E L +L L +N+++++ SSL L L +N I
Sbjct 192 CYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPG-----LPSSLMYLSLENNSISSI 246
Query 213 SPGCFHAIGRLFGLFLNNVQL 233
F + +L L +++ +L
Sbjct 247 PEKYFDKLPKLHTLRMSHNKL 267
Score = 53.5 bits (127), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 63/204 (31%), Positives = 99/204 (49%), Gaps = 20/204 (10%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L+L HN L P F L L +G+N ISKL+ L L +L+L +N L
Sbjct 140 NLLQLHLEHNNLEEFP---FPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYL 196
Query 112 --SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
S L DK FA L +L+L SN ++ + P +L+ L L +N +SS +
Sbjct 197 HDSLLKDKIFAKMEKLMQLNLCSNRLESM---PPGLPSSLMYLSLENNSISSIPEKYFDK 253
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L L L +S+NK+Q + +IF ++ +L + N++K+ F+ L L+L
Sbjct 254 LPKLHTLRMSHNKLQDIP---YNIFNLPNIVELSVGHNKLKQ----AFYIPRNLEHLYLQ 306
Query 230 NVQLGPSLTEKLCLELANTSIRNL 253
N ++ EK+ L + SI L
Sbjct 307 NNEI-----EKMNLTVMCPSIDPL 325
Score = 47.4 bits (111), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 59/238 (25%), Positives = 107/238 (45%), Gaps = 27/238 (11%)
Query 299 QLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK-QSIS---LASLPKI-------- 346
++ +L++N I+ + ++S +++ +NL + K Q I A LP +
Sbjct 90 HIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHN 149
Query 347 --DDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
++F F K LE L + N+I +++N GL+NL L L ++ L ++ F +
Sbjct 150 NLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKM 209
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS 464
L LNL N++ + S L +L + + ++ I ++ + L + + +S
Sbjct 210 EK--LMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKY----FDKLPKLHTLRMS 263
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
+NK + N F L P++ L + LK P RNL L L NN I +N
Sbjct 264 HNKLQDIPYNIFNL-PNIVELSVGHNKLKQAFYIP------RNLEHLYLQNNEIEKMN 314
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 62/246 (25%), Positives = 116/246 (47%), Gaps = 29/246 (12%)
Query 125 LTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL--GTQVQLENLQELLLSNNK 182
+ +L+L N I+ + N F+ +L ++LSHN + S K+ G +L NL +L L +N
Sbjct 91 IQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNN 150
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPS-LTEKL 241
+ EE SL++L L N+I + + L L L L S L +K+
Sbjct 151 L-----EEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKI 205
Query 242 CLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
++ + L+L +++L + GL ++L L L N+++ + F LP+L
Sbjct 206 FAKME--KLMQLNLCSNRLESMPP----GLP-SSLMYLSLENNSISSIPEKYFDKLPKLH 258
Query 302 YFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLN 361
+ +N +Q + +++ L N+ L++ + KQ +F + LEHL
Sbjct 259 TLRMSHNKLQDI-PYNIFNLPNIVELSVGHNKLKQ-------------AFYIPRNLEHLY 304
Query 362 MEDNDI 367
+++N+I
Sbjct 305 LQNNEI 310
Score = 42.0 bits (97), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 47/175 (27%), Positives = 86/175 (49%), Gaps = 16/175 (9%)
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
I ++YL +N+ +T NSF L+ + L +K+ F L NL L L +NN
Sbjct 91 IQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNN 150
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDE- 576
+ + + LE+L L +N +++L +A + GL +L +L+L N +
Sbjct 151 LEEFPFPLPKSLERLL---LGYNEISKLQTNA--------MDGLVNLTMLDLCYNYLHDS 199
Query 577 -IPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+ ++F + +L ++L N L ++P + SL L+L+ N I+S+ +K F
Sbjct 200 LLKDKIFAKMEKLMQLNLCSNRLESMPPGL---PSSLMYLSLENNSISSIPEKYF 251
>5yq5_B B Osteomodulin
Length=430
Score = 57.0 bits (136), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 56/201 (28%), Positives = 98/201 (49%), Gaps = 13/201 (6%)
Query 37 CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTIS--KLEPEL 94
C + KL +P+ +P +I L L N++ + A +F + L +++ N I K++ +
Sbjct 76 CDNRKLKTIPN-IPMHIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGV 134
Query 95 CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
KLP L L+L+HN L + F +L L L N I K++ N NL LDL
Sbjct 135 FAKLPNLLQLHLEHNNLEEFP---FPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDL 191
Query 155 SHNGLSSTKLGTQV--QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
+N L + L ++ ++E L +L L +N+++++ SSL L L +N I
Sbjct 192 CYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPG-----LPSSLMYLSLENNSISSI 246
Query 213 SPGCFHAIGRLFGLFLNNVQL 233
F + +L L +++ +L
Sbjct 247 PEKYFDKLPKLHTLRMSHNKL 267
Score = 53.5 bits (127), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 63/204 (31%), Positives = 99/204 (49%), Gaps = 20/204 (10%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L+L HN L P F L L +G+N ISKL+ L L +L+L +N L
Sbjct 140 NLLQLHLEHNNLEEFP---FPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYL 196
Query 112 --SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
S L DK FA L +L+L SN ++ + P +L+ L L +N +SS +
Sbjct 197 HDSLLKDKIFAKMEKLMQLNLCSNRLESM---PPGLPSSLMYLSLENNSISSIPEKYFDK 253
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L L L +S+NK+Q + +IF ++ +L + N++K+ F+ L L+L
Sbjct 254 LPKLHTLRMSHNKLQDIP---YNIFNLPNIVELSVGHNKLKQ----AFYIPRNLEHLYLQ 306
Query 230 NVQLGPSLTEKLCLELANTSIRNL 253
N ++ EK+ L + SI L
Sbjct 307 NNEI-----EKMNLTVMCPSIDPL 325
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 59/238 (25%), Positives = 107/238 (45%), Gaps = 27/238 (11%)
Query 299 QLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTK-QSIS---LASLPKI-------- 346
++ +L++N I+ + ++S +++ +NL + K Q I A LP +
Sbjct 90 HIQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHN 149
Query 347 --DDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSL 404
++F F K LE L + N+I +++N GL+NL L L ++ L ++ F +
Sbjct 150 NLEEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKM 209
Query 405 AHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS 464
L LNL N++ + S L +L + + ++ I ++ + L + + +S
Sbjct 210 EK--LMQLNLCSNRLESMPPGLPSSLMYLSLENNSISSIPEKY----FDKLPKLHTLRMS 263
Query 465 YNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
+NK + N F L P++ L + LK P RNL L L NN I +N
Sbjct 264 HNKLQDIPYNIFNL-PNIVELSVGHNKLKQAFYIP------RNLEHLYLQNNEIEKMN 314
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 62/246 (25%), Positives = 116/246 (47%), Gaps = 29/246 (12%)
Query 125 LTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL--GTQVQLENLQELLLSNNK 182
+ +L+L N I+ + N F+ +L ++LSHN + S K+ G +L NL +L L +N
Sbjct 91 IQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNN 150
Query 183 IQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPS-LTEKL 241
+ EE SL++L L N+I + + L L L L S L +K+
Sbjct 151 L-----EEFPFPLPKSLERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKI 205
Query 242 CLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLE 301
++ + L+L +++L + GL ++L L L N+++ + F LP+L
Sbjct 206 FAKME--KLMQLNLCSNRLESMPP----GLP-SSLMYLSLENNSISSIPEKYFDKLPKLH 258
Query 302 YFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLN 361
+ +N +Q + +++ L N+ L++ + KQ +F + LEHL
Sbjct 259 TLRMSHNKLQDI-PYNIFNLPNIVELSVGHNKLKQ-------------AFYIPRNLEHLY 304
Query 362 MEDNDI 367
+++N+I
Sbjct 305 LQNNEI 310
Score = 41.6 bits (96), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 47/175 (27%), Positives = 86/175 (49%), Gaps = 16/175 (9%)
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
I ++YL +N+ +T NSF L+ + L +K+ F L NL L L +NN
Sbjct 91 IQQLYLQFNEIEAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNN 150
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDE- 576
+ + + LE+L L +N +++L +A + GL +L +L+L N +
Sbjct 151 LEEFPFPLPKSLERLL---LGYNEISKLQTNA--------MDGLVNLTMLDLCYNYLHDS 199
Query 577 -IPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
+ ++F + +L ++L N L ++P + SL L+L+ N I+S+ +K F
Sbjct 200 LLKDKIFAKMEKLMQLNLCSNRLESMPPGL---PSSLMYLSLENNSISSIPEKYF 251
>7w3v_B C Membrane-localized LRR receptor-like protein
Length=934
Score = 57.4 bits (137), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 116/468 (25%), Positives = 197/468 (42%), Gaps = 77/468 (16%)
Query 244 ELANTSIRNLS---LSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQL 300
E+AN+S+ +LS L ++ S+++ ++L T+LT +DLS N L+ +D F L L
Sbjct 231 EIANSSLISLSVLHLCCNEFSSSAKYSWLFNFSTSLTSIDLSNNQLDGQIDDRFGNLMYL 290
Query 301 EYFFLEYN-NIQHLFSHSLHGLFNVRYLNLKRSFTKQSI------------SLASLPKID 347
E+ L N++ S L +RYL++ + T Q + +L L D
Sbjct 291 EHLNLANELNLKGGIPSSFGNLTRLRYLDMSNTRTYQWLPELFVRLSGSRKTLEVLGLND 350
Query 348 DFSFQWL------KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS-----------F 390
+ F L L+ L ++ N + G F + +L+YL LS++ F
Sbjct 351 NSMFGSLVDVTRFSALKRLYLQKNVLNGFFMERFGQVSSLEYLDLSDNQMRGPLPDLALF 410
Query 391 TSLRTL---TNETFVSLAH-----SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE 442
SLR L +N + S L IL+++ N++ + ++ L +LE D N
Sbjct 411 PSLRELHLGSNHFNGRIPQGIGKLSQLKILDVSSNRLEGLP-ESMGQLSNLESFDASYNV 469
Query 443 IGQELTGQEWRGLENIFEIYLSYNKYLQLTR--------------NSFALVPSLQRLMLR 488
+ +T L ++ ++ LS+N T S L PS + +
Sbjct 470 LKGTITESHLSNLSSLVDLDLSFNSLALKTSIDWLPPFQLQVINLPSCNLGPSFPKWLQS 529
Query 489 R-------VALKNV-DSSPSPFQPLR-NLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
+ ++L N+ D+ PS F L ++ IL+LSNN I+ D++E ++DL
Sbjct 530 QNNYTVLDISLANISDALPSWFSGLPPDIKILNLSNNQISGRVSDLIENAYDYMVIDLSS 589
Query 540 NNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLN 599
NN + GP+ + +++ I L N F + K +DL N +
Sbjct 590 NNFS---------GPLPLVP--TNVQIFYLHKNQFFGSISSICKSTTGATSLDLSHNQFS 638
Query 600 TLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPF 647
+ N +L LNL N + + G + NL L MR N F
Sbjct 639 GELPDCWMNATNLAVLNLAYNNFSGKLPQSLG-SLTNLEALYMRQNSF 685
Score = 37.0 bits (84), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 33/111 (30%), Positives = 47/111 (42%), Gaps = 1/111 (1%)
Query 49 LPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQH 108
+PTN+ + L NQ ++ + TSLD+ N S P+ L VLNL +
Sbjct 599 VPTNVQIFYLHKNQFFGSISSICKSTTGATSLDLSHNQFSGELPDCWMNATNLAVLNLAY 658
Query 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
N S ++ TNL L++ NS Q +L LDL N L
Sbjct 659 NNFSGKLPQSLGSLTNLEALYMRQNSFSGXXXXXXXCQ-SLQILDLGGNKL 708
>5xjo_D C Protein TOO MANY MOUTHS
Length=374
Score = 56.6 bits (135), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 49/146 (34%), Positives = 71/146 (49%), Gaps = 12/146 (8%)
Query 42 LTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
L +PD+L TN+ VL+L N L +F R+S L SLD+ N ++ P LP
Sbjct 121 LGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFV--LP 178
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN----LITLDLS 155
L VL+L N L+ T C +L ++ L N + P + +N L+ LDLS
Sbjct 179 ALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV----TGPIPESQNRLNQLVLLDLS 234
Query 156 HNGLSSTKLGTQVQLENLQELLLSNN 181
+N LS + L +LQ L+L N
Sbjct 235 YNRLSGPFPSSLQGLNSLQALMLKGN 260
Score = 50.4 bits (119), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 76/306 (25%), Positives = 123/306 (40%), Gaps = 43/306 (14%)
Query 280 DLSYNNLNVVGNDSFAWLPQL---EYFFLE----YNNIQHLFSHSLHGLFNVRYL---NL 329
D Y+ + GND A +P + + +E +N+ H+ S S L + +
Sbjct 9 DAVYDIMRATGNDWAAAIPDVCRGRWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDP 68
Query 330 KRSFTKQSIS-------------LASLP-KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMF 375
+RS+ +S++ L P +I F + L+ L + +N G +
Sbjct 69 QRSYVSESLTRLKHLKALFFYRCLGRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDEL 128
Query 376 TGLINLKYLSLS------------NSFTSLRTLT------NETFVSLAHSPLHILNLTKN 417
L NLK L L N F+ LR+L + L +L+L +N
Sbjct 129 GNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQN 188
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + G L +DL N + + + R L + + LSYN+ +S
Sbjct 189 LLTGPVPPTLTSCGSLIKIDLSRNRVTGPIPESQNR-LNQLVLLDLSYNRLSGPFPSSLQ 247
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDL 537
+ SLQ LML+ + + F+ L+NL IL LSN NI L L L +L L
Sbjct 248 GLNSLQALMLKGNNKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 307
Query 538 QHNNLA 543
+ NNL
Sbjct 308 EGNNLT 313
Score = 35.0 bits (79), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 14/126 (11%)
Query 554 PIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLNNLN-TLPASVFNNQVS 611
P + + S L L L NGF IP E+ +L LK++DL N+LN ++P S FN
Sbjct 100 PAFLGRLGSSLQTLVLRENGFLGPIPDEL-GNLTNLKVLDLHKNHLNGSIPLS-FNRFSG 157
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN-------PFDCTCESIAWFVNWINET 664
L+SL+L N +T PA L+ LD+ N P +C S+ N
Sbjct 158 LRSLDLSGNRLTGSIPGFVLPA---LSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 214
Query 665 HTNIPE 670
IPE
Sbjct 215 TGPIPE 220
Score = 33.5 bits (75), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 64/241 (27%), Positives = 101/241 (42%), Gaps = 43/241 (18%)
Query 400 TFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIF 459
F+ S L L L +N D L +L+VLDL N +
Sbjct 101 AFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGS------------- 147
Query 460 EIYLSYNKY-----LQLTRNSFA------LVPSLQRLMLRRVALKNVDSSPSP--FQPLR 506
I LS+N++ L L+ N ++P+L L L +N+ + P P
Sbjct 148 -IPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLN----QNLLTGPVPPTLTSCG 202
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+L +DLS N + + L +L +LDL +N L+ + + L+GL+ L
Sbjct 203 SLIKIDLSRNRVTGPIPESQNRLNQLVLLDLSYNRLSGPFPSS--------LQGLNSLQA 254
Query 567 LNLESNG--FDEIPVEVFKDLFELKIIDLGLNNL-NTLPASVFNNQVSLKSLNLQKNLIT 623
L L+ N IP FK L L I+ L N+ ++P S+ SL+ L+L+ N +T
Sbjct 255 LMLKGNNKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSL-TRLNSLRVLHLEGNNLT 313
Query 624 S 624
Sbjct 314 G 314
>5xjo_E D Protein TOO MANY MOUTHS
Length=374
Score = 56.6 bits (135), Expect = 6e-07, Method: Compositional matrix adjust.
Identities = 49/146 (34%), Positives = 71/146 (49%), Gaps = 12/146 (8%)
Query 42 LTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
L +PD+L TN+ VL+L N L +F R+S L SLD+ N ++ P LP
Sbjct 121 LGPIPDELGNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFV--LP 178
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN----LITLDLS 155
L VL+L N L+ T C +L ++ L N + P + +N L+ LDLS
Sbjct 179 ALSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV----TGPIPESQNRLNQLVLLDLS 234
Query 156 HNGLSSTKLGTQVQLENLQELLLSNN 181
+N LS + L +LQ L+L N
Sbjct 235 YNRLSGPFPSSLQGLNSLQALMLKGN 260
Score = 50.4 bits (119), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 76/306 (25%), Positives = 123/306 (40%), Gaps = 43/306 (14%)
Query 280 DLSYNNLNVVGNDSFAWLPQL---EYFFLE----YNNIQHLFSHSLHGLFNVRYL---NL 329
D Y+ + GND A +P + + +E +N+ H+ S S L + +
Sbjct 9 DAVYDIMRATGNDWAAAIPDVCRGRWHGIECMPDQDNVYHVVSLSFGALSDDTAFPTCDP 68
Query 330 KRSFTKQSIS-------------LASLP-KIDDFSFQWLKCLEHLNMEDNDIPGIKSNMF 375
+RS+ +S++ L P +I F + L+ L + +N G +
Sbjct 69 QRSYVSESLTRLKHLKALFFYRCLGRAPQRIPAFLGRLGSSLQTLVLRENGFLGPIPDEL 128
Query 376 TGLINLKYLSLS------------NSFTSLRTLT------NETFVSLAHSPLHILNLTKN 417
L NLK L L N F+ LR+L + L +L+L +N
Sbjct 129 GNLTNLKVLDLHKNHLNGSIPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLNQN 188
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFA 477
++ + G L +DL N + + + R L + + LSYN+ +S
Sbjct 189 LLTGPVPPTLTSCGSLIKIDLSRNRVTGPIPESQNR-LNQLVLLDLSYNRLSGPFPSSLQ 247
Query 478 LVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDL 537
+ SLQ LML+ + + F+ L+NL IL LSN NI L L L +L L
Sbjct 248 GLNSLQALMLKGNNKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSLTRLNSLRVLHL 307
Query 538 QHNNLA 543
+ NNL
Sbjct 308 EGNNLT 313
Score = 35.0 bits (79), Expect = 3.7, Method: Compositional matrix adjust.
Identities = 42/126 (33%), Positives = 58/126 (46%), Gaps = 14/126 (11%)
Query 554 PIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLNNLN-TLPASVFNNQVS 611
P + + S L L L NGF IP E+ +L LK++DL N+LN ++P S FN
Sbjct 100 PAFLGRLGSSLQTLVLRENGFLGPIPDEL-GNLTNLKVLDLHKNHLNGSIPLS-FNRFSG 157
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN-------PFDCTCESIAWFVNWINET 664
L+SL+L N +T PA L+ LD+ N P +C S+ N
Sbjct 158 LRSLDLSGNRLTGSIPGFVLPA---LSVLDLNQNLLTGPVPPTLTSCGSLIKIDLSRNRV 214
Query 665 HTNIPE 670
IPE
Sbjct 215 TGPIPE 220
Score = 33.5 bits (75), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 64/241 (27%), Positives = 101/241 (42%), Gaps = 43/241 (18%)
Query 400 TFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIF 459
F+ S L L L +N D L +L+VLDL N +
Sbjct 101 AFLGRLGSSLQTLVLRENGFLGPIPDELGNLTNLKVLDLHKNHLNGS------------- 147
Query 460 EIYLSYNKY-----LQLTRNSFA------LVPSLQRLMLRRVALKNVDSSPSP--FQPLR 506
I LS+N++ L L+ N ++P+L L L +N+ + P P
Sbjct 148 -IPLSFNRFSGLRSLDLSGNRLTGSIPGFVLPALSVLDLN----QNLLTGPVPPTLTSCG 202
Query 507 NLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHI 566
+L +DLS N + + L +L +LDL +N L+ + + L+GL+ L
Sbjct 203 SLIKIDLSRNRVTGPIPESQNRLNQLVLLDLSYNRLSGPFPSS--------LQGLNSLQA 254
Query 567 LNLESNG--FDEIPVEVFKDLFELKIIDLGLNNL-NTLPASVFNNQVSLKSLNLQKNLIT 623
L L+ N IP FK L L I+ L N+ ++P S+ SL+ L+L+ N +T
Sbjct 255 LMLKGNNKFSTTIPENAFKGLKNLMILVLSNTNIQGSIPKSL-TRLNSLRVLHLEGNNLT 313
Query 624 S 624
Sbjct 314 G 314
>5cmp_D D Leucine-rich repeat transmembrane protein FLRT3
Length=333
Score = 56.2 bits (134), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 81/306 (26%), Positives = 130/306 (42%), Gaps = 40/306 (13%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLP-AANFTRYSQLTSLDVGFNT 86
C C+ LT +P +P + T L L +NQ+ ++ ++ + + N+
Sbjct 11 CRCDAGFIYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLLKVERIYLYHNS 70
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIKNNPFV 144
+ + L + +K L+LQ N + ++ + + L ELHL NS+ I+ F
Sbjct 71 LDEFPTNLPK---YVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFR 127
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
L L LS N LS+ G +E EL L +N+I + S L +SLK+L L
Sbjct 128 DSNYLRLLFLSRNHLSTIPWGLPRTIE---ELRLDDNRISTISSPSLQGL--TSLKRLVL 182
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
N LNN LG +K+ L N + LSL + L+
Sbjct 183 DGN-------------------LLNNHGLG----DKVFFNLVN--LTELSLVRNSLTAAP 217
Query 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNV 324
+ L TNL L L N++N V ++F++L QL + NN+ +L L N+
Sbjct 218 ----VNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNI 273
Query 325 RYLNLK 330
L L+
Sbjct 274 TQLILR 279
Score = 50.8 bits (120), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 70/280 (25%), Positives = 120/280 (43%), Gaps = 44/280 (16%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L +N I I D+ S + +LE L L N + +I E + YL+L
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAV----------SIEEGAFRDSNYLRL 134
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
L L R L + P+ R + L L +N I+ I+ L+GL
Sbjct 135 -------------LFLSRNHLSTI-----PWGLPRTIEELRLDDNRISTISSPSLQGLTS 176
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L+ L L N L + G ++F L +L L+L N PV + L+ +
Sbjct 177 LKRLVLDGN----LLNNHGLGDKVFF--NLVNLTELSLVRNSLTAAPVNLPGT--NLRKL 228
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTC 651
L N++N +P + F+ L L++ N ++++ + +F N+T+L +R NP+ C C
Sbjct 229 YLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD-DLDNITQLILRNNPWYCGC 287
Query 652 ESIAWFVNWINE--THTNIPELSSHYLCNTPPHYHGFPVR 689
+ + W +W+ N+ L +C P G ++
Sbjct 288 K-MKWVRDWLQSLPVKVNVRGL----MCQAPEKVRGMAIK 322
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 31/210 (15%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L NN+ + DS + +P LE L+ N++ + G F R N R
Sbjct 85 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE--EGAF--RDSNYLRLLFLSRN 140
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS--------- 389
L+++P + + +E L ++DN I I S GL +LK L L +
Sbjct 141 HLSTIP------WGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGD 194
Query 390 --FTSLRTLTNETFV--SLAHSPLHI-------LNLTKNKISKIESDAFSWLGHLEVLDL 438
F +L LT + V SL +P+++ L L N I+++ +AFS+L L LD+
Sbjct 195 KVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 254
Query 439 GLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
N + G + L+NI ++ L N +
Sbjct 255 SNNNLSNLPQGI-FDDLDNITQLILRNNPW 283
Score = 43.1 bits (100), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 41/142 (29%), Positives = 68/142 (48%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ +P LP I L L N++ + + + + L L + N ++ L ++ L
Sbjct 142 LSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 201
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L+L N L+ TNL +L+L N I ++ N F + L LD+S+N L
Sbjct 202 NLTELSLVRNSLTAAPVNLPG--TNLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 259
Query 160 SSTKLGTQVQLENLQELLLSNN 181
S+ G L+N+ +L+L NN
Sbjct 260 SNLPQGIFDDLDNITQLILRNN 281
Score = 40.8 bits (94), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 36/221 (16%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS-- 403
+D+F K ++ L++++N+I I + + + L+ L L ++ S ++ F
Sbjct 71 LDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSN 130
Query 404 -----------LAHSP------LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
L+ P + L L N+IS I S + L L+ L L N +
Sbjct 131 YLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNH 190
Query 447 LTGQE-WRGLENIFEIYLSYNKYLQLTRNSFALVP------SLQRLMLRRVALKNVDSSP 499
G + + L N+ E L L RNS P +L++L L+ + V P
Sbjct 191 GLGDKVFFNLVNLTE--------LSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRV--PP 240
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+ F LR L LD+SNNN++N+ + + L+ + L L++N
Sbjct 241 NAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 281
>4rca_B B SLIT and NTRK-like protein 1
Length=251
Score = 55.1 bits (131), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 51/189 (27%), Positives = 87/189 (46%), Gaps = 16/189 (8%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
P+ F N L + NN + I GL+ ++ L + +N + K FL
Sbjct 56 PNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFRKQT-------FL 108
Query 559 KGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQ 618
GL L L + N +I F+DL +L+++ L N ++TLPA+VF V + L+L+
Sbjct 109 -GLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILNDNLISTLPANVF-QYVPITHLDLR 166
Query 619 KNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPE--LSSHYL 676
N + ++ + + E+ + NP+DCTC+ ++ W+ NIP+ L +
Sbjct 167 GNRLKTLPYEEVLEQIPGIAEILLEDNPWDCTCDLLS-LKEWLE----NIPKNALIGRVV 221
Query 677 CNTPPHYHG 685
C P G
Sbjct 222 CEAPTRLQG 230
Score = 43.1 bits (100), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 2/103 (2%)
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L L NS+ ++ N F N ++L + +NGL G + L+ ++ L ++NNKI++ +
Sbjct 44 LFLHGNSLTRLFPNEFANFYNAVSLHMENNGLHEIVPGAFLGLQLVKRLHINNNKIKSFR 103
Query 188 SEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+ L+ L+ N +++ PG F + +L L LN+
Sbjct 104 KQTF--LGLDDLEYLQADFNLLRDIDPGAFQDLNKLEVLILND 144
Score = 38.1 bits (87), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 42/170 (25%), Positives = 75/170 (44%), Gaps = 14/170 (8%)
Query 299 QLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLE 358
Q + FL N++ LF + +N L+++ + L +I +F L+ ++
Sbjct 40 QFYHLFLHGNSLTRLFPNEFANFYNAVSLHMENN---------GLHEIVPGAFLGLQLVK 90
Query 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
L++ +N I + F GL +L+YL F LR + F L + L +L L N
Sbjct 91 RLHINNNKIKSFRKQTFLGLDDLEYLQA--DFNLLRDIDPGAFQDL--NKLEVLILNDNL 146
Query 419 ISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
IS + ++ F ++ + LDL N + + + I EI L N +
Sbjct 147 ISTLPANVFQYVP-ITHLDLRGNRLKTLPYEEVLEQIPGIAEILLEDNPW 195
>2z82_A A Toll-like receptor 2, Variable lymphocyte receptor B
Length=549
Score = 56.6 bits (135), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 131/558 (23%), Positives = 227/558 (41%), Gaps = 107/558 (19%)
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+LDLS N ++ G NLQ L+L +++I ++ + ++ SL+ L+LS N +
Sbjct 30 SLDLSFNKITYIGHGDLRACANLQVLILKSSRINTIEGDAF--YSLGSLEHLDLSDNHLS 87
Query 211 EFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNLSLSNSQ-LSTTSNTTF 268
S F G L L N+ P T + N T+++ L + N + S F
Sbjct 88 SLSSSWF---GPLSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDF 144
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
GL T+L L++ +L + S + + + L + L L +VRYL
Sbjct 145 AGL--TSLNELEIKALSLRNYQSQSLKSIRDIHHLTLHLSESAFLLEIFADILSSVRYLE 202
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
L R + LP +D+ S +K F G +
Sbjct 203 L-RDTNLARFQFSPLP-VDEVS-----------------SPMKKLAFRGSV--------- 234
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI-----------ESDAFSWLGHLEVLD 437
LT+E+F L +IL L++ + ESD S LG +E +
Sbjct 235 -------LTDESFNELLKLLRYILELSEVEFDDCTLNGLGDFNPSESDVVSELGKVETVT 287
Query 438 L------------GLNEIGQELTGQEWRGLEN--IFEIYLSYNKYL-------------- 469
+ L+ + L + +EN +F + S++++L
Sbjct 288 IRRLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMV 347
Query 470 -QLTRNSF--ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
+ +NS PSLQ L+L + L+++ + L+NLT LD+S N + D
Sbjct 348 EEYLKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPMPDSC- 406
Query 527 EGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLF 586
+ EK+ L+L + R+ K P L +L++ +N D +F L
Sbjct 407 QWPEKMRFLNLSSTGI-RVVKTCIP----------QTLEVLDVSNNNLDSF--SLF--LP 451
Query 587 ELKIIDLGLNNLNTLP-ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L+ + + N L TLP AS+F + +K + +N + SV +F +L ++ + N
Sbjct 452 RLQELYISRNKLKTLPDASLFPVLLVMK---ISRNQLKSVPDGIFD-RLTSLQKIWLHTN 507
Query 646 PFDCTCESIAWFVNWINE 663
P+DC+C I + W+N+
Sbjct 508 PWDCSCPRIDYLSRWLNK 525
>2z81_A A Toll-like receptor 2, Variable lymphocyte receptor B
Length=549
Score = 56.6 bits (135), Expect = 9e-07, Method: Compositional matrix adjust.
Identities = 131/558 (23%), Positives = 227/558 (41%), Gaps = 107/558 (19%)
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+LDLS N ++ G NLQ L+L +++I ++ + ++ SL+ L+LS N +
Sbjct 30 SLDLSFNKITYIGHGDLRACANLQVLILKSSRINTIEGDAF--YSLGSLEHLDLSDNHLS 87
Query 211 EFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNLSLSNSQ-LSTTSNTTF 268
S F G L L N+ P T + N T+++ L + N + S F
Sbjct 88 SLSSSWF---GPLSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDF 144
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
GL T+L L++ +L + S + + + L + L L +VRYL
Sbjct 145 AGL--TSLNELEIKALSLRNYQSQSLKSIRDIHHLTLHLSESAFLLEIFADILSSVRYLE 202
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
L R + LP +D+ S +K F G +
Sbjct 203 L-RDTNLARFQFSPLP-VDEVS-----------------SPMKKLAFRGSV--------- 234
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI-----------ESDAFSWLGHLEVLD 437
LT+E+F L +IL L++ + ESD S LG +E +
Sbjct 235 -------LTDESFNELLKLLRYILELSEVEFDDCTLNGLGDFNPSESDVVSELGKVETVT 287
Query 438 L------------GLNEIGQELTGQEWRGLEN--IFEIYLSYNKYL-------------- 469
+ L+ + L + +EN +F + S++++L
Sbjct 288 IRRLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMV 347
Query 470 -QLTRNSF--ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
+ +NS PSLQ L+L + L+++ + L+NLT LD+S N + D
Sbjct 348 EEYLKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPMPDSC- 406
Query 527 EGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLF 586
+ EK+ L+L + R+ K P L +L++ +N D +F L
Sbjct 407 QWPEKMRFLNLSSTGI-RVVKTCIP----------QTLEVLDVSNNNLDSF--SLF--LP 451
Query 587 ELKIIDLGLNNLNTLP-ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L+ + + N L TLP AS+F + +K + +N + SV +F +L ++ + N
Sbjct 452 RLQELYISRNKLKTLPDASLFPVLLVMK---ISRNQLKSVPDGIFD-RLTSLQKIWLHTN 507
Query 646 PFDCTCESIAWFVNWINE 663
P+DC+C I + W+N+
Sbjct 508 PWDCSCPRIDYLSRWLNK 525
>6tl8_B B Myeloid cell surface antigen CD33,Leucine-rich repeat
and fibronectin type-III domain-containing protein 4
Length=299
Score = 55.5 bits (132), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 80/165 (48%), Gaps = 12/165 (7%)
Query 445 QELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQP 504
Q L ++R + + ++ LS N ++ SF + SL+ L L L + SS S P
Sbjct 65 QALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRLVELGSS-SLRGP 123
Query 505 LRNLTILDLSNNNIANINDDMLEG-LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
+ NL L LS N + I + L+ LE LD+ +NNL ++ P + +
Sbjct 124 V-NLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQV--------PWAGIGSMPA 174
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTL-PASVFN 607
LH LNL+ N D +P VF L +L +DL N L TL P +F+
Sbjct 175 LHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPLFS 219
Score = 51.2 bits (121), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 49/164 (30%), Positives = 69/164 (42%), Gaps = 15/164 (9%)
Query 488 RRVALKNVDS-----SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
R V L+ D+ P F+ + L L LS N I I LE L L L N L
Sbjct 53 RTVELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRL 112
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFE-LKIIDLGLNNLNTL 601
L + L+G +L L L N I F D + L+ +D+ NNL +
Sbjct 113 VELGSSS--------LRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQV 164
Query 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
P + + +L +LNL NLI ++ VF L+ LD+ N
Sbjct 165 PWAGIGSMPALHTLNLDHNLIDALPPGVFA-QLSQLSRLDLTSN 207
Score = 48.9 bits (115), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 30/95 (32%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query 50 PTNITVLNLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQH 108
P N+ L L+ NQL R+ F + L LDV +N + ++ +P L LNL H
Sbjct 123 PVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVPWAGIGSMPALHTLNLDH 182
Query 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
N + L FA + L+ L L SN + + +P
Sbjct 183 NLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPL 217
Score = 44.3 bits (103), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 57/234 (24%), Positives = 84/234 (36%), Gaps = 26/234 (11%)
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
E+ L+ N L F + L L L R A+ + + F L +L L L N +
Sbjct 56 ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARS--FGDLESLRSLHLDGNRLV 113
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
+ L G L+ L L N L R+ P F L L L++ N ++P
Sbjct 114 ELGSSSLRGPVNLQHLILSGNQLGRI-------APGAFDDFLDSLEDLDVSYNNLRQVPW 166
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
+ L ++L N ++ LP VF L L+L N + ++ P F
Sbjct 167 AGIGSMPALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPD---PLFSXXXX 223
Query 640 ---------LDMRFNPFDCTCESIAWFVNWIN----ETHTNIPELSSHYLCNTP 680
L NP C CE + W ET + P L+ Y P
Sbjct 224 XXXXXXXXVLSFSGNPLHCNCE-LLWLRRLARPDDLETCASPPTLAGRYFWAVP 276
Score = 38.9 bits (89), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 46/146 (32%), Positives = 64/146 (44%), Gaps = 20/146 (14%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L++N IQAL + F N + L L LS N I F + L L L+ +L
Sbjct 56 ELRLADNFIQALGPPD---FRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRL 112
Query 234 GPSLTEKLCLELANTSIRN------LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN 287
+EL ++S+R L LS +QL + F +L LD+SYNNL
Sbjct 113 ---------VELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDF-LDSLEDLDVSYNNLR 162
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHL 313
V +P L L++N I L
Sbjct 163 QVPWAGIGSMPALHTLNLDHNLIDAL 188
Score = 38.9 bits (89), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 42/168 (25%), Positives = 78/168 (46%), Gaps = 6/168 (4%)
Query 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
L + DN I + F + L L+LS + ++ + +F L L L+L N+
Sbjct 56 ELRLADNFIQALGPPDFRNMTGLVDLTLSRN--AITRIGARSFGDLES--LRSLHLDGNR 111
Query 419 ISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFAL 478
+ ++ S + +L+ L L N++G+ G L+++ ++ +SYN Q+
Sbjct 112 LVELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVPWAGIGS 171
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
+P+L L L + + P F L L+ LDL++N +A + D L
Sbjct 172 MPALHTLNLDHNLIDAL--PPGVFAQLSQLSRLDLTSNRLATLAPDPL 217
>2v70_B B SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Length=220
Score = 54.3 bits (129), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 46/202 (23%), Positives = 82/202 (41%), Gaps = 49/202 (24%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC DCS+ KL ++P+ +P L L +N+ L A +
Sbjct 8 KCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFK------------- 54
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
KLP L+ +N +N+++ + + F + + E+ L SN ++ +++ F
Sbjct 55 ----------KLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKG- 103
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
LE+L+ L+L +N+I + ++ SS++ L L
Sbjct 104 -----------------------LESLKTLMLRSNRITCVGNDSF--IGLSSVRLLSLYD 138
Query 207 NQIKEFSPGCFHAIGRLFGLFL 228
NQI +PG F + L L L
Sbjct 139 NQITTVAPGAFDTLHSLSTLNL 160
Score = 43.9 bits (102), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 45/189 (24%), Positives = 75/189 (40%), Gaps = 40/189 (21%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKL-EILDLQHNNLARLWKHANPGGPIYFLKG 560
F+ L L ++ SNN I +I + EG + EIL
Sbjct 53 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEIL------------------------- 87
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L SN + + ++FK L LK + L N + + F S++ L+L N
Sbjct 88 --------LTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDN 139
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTP 680
IT+V F +L+ L++ NPF+C C +AW W+ + ++ + C P
Sbjct 140 QITTVAPGAFD-TLHSLSTLNLLANPFNCNC-YLAWLGEWLRKKRI----VTGNPRCQKP 193
Query 681 PHYHGFPVR 689
P++
Sbjct 194 YFLKEIPIQ 202
Score = 35.0 bits (79), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 39/156 (25%), Positives = 62/156 (40%), Gaps = 32/156 (21%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L+NN+ L E IF L+K+ S+N+I + G F
Sbjct 36 ELRLNNNEFTVL--EATGIFKKLPQLRKINFSNNKITDIEEGAFEGA------------- 80
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
+ + + L++++L + F GL+ +L L L N + VGNDS
Sbjct 81 --------------SGVNEILLTSNRLENVQHKMFKGLE--SLKTLMLRSNRITCVGNDS 124
Query 294 FAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
F L + L N I + + L ++ LNL
Sbjct 125 FIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNL 160
>2v70_D D SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Length=220
Score = 54.3 bits (129), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 46/202 (23%), Positives = 82/202 (41%), Gaps = 49/202 (24%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC DCS+ KL ++P+ +P L L +N+ L A +
Sbjct 8 KCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFK------------- 54
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
KLP L+ +N +N+++ + + F + + E+ L SN ++ +++ F
Sbjct 55 ----------KLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKG- 103
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
LE+L+ L+L +N+I + ++ SS++ L L
Sbjct 104 -----------------------LESLKTLMLRSNRITCVGNDSF--IGLSSVRLLSLYD 138
Query 207 NQIKEFSPGCFHAIGRLFGLFL 228
NQI +PG F + L L L
Sbjct 139 NQITTVAPGAFDTLHSLSTLNL 160
Score = 43.9 bits (102), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 45/189 (24%), Positives = 75/189 (40%), Gaps = 40/189 (21%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKL-EILDLQHNNLARLWKHANPGGPIYFLKG 560
F+ L L ++ SNN I +I + EG + EIL
Sbjct 53 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEIL------------------------- 87
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L SN + + ++FK L LK + L N + + F S++ L+L N
Sbjct 88 --------LTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDN 139
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTP 680
IT+V F +L+ L++ NPF+C C +AW W+ + ++ + C P
Sbjct 140 QITTVAPGAFD-TLHSLSTLNLLANPFNCNC-YLAWLGEWLRKKRI----VTGNPRCQKP 193
Query 681 PHYHGFPVR 689
P++
Sbjct 194 YFLKEIPIQ 202
Score = 35.0 bits (79), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 39/156 (25%), Positives = 62/156 (40%), Gaps = 32/156 (21%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L+NN+ L E IF L+K+ S+N+I + G F
Sbjct 36 ELRLNNNEFTVL--EATGIFKKLPQLRKINFSNNKITDIEEGAFEGA------------- 80
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
+ + + L++++L + F GL+ +L L L N + VGNDS
Sbjct 81 --------------SGVNEILLTSNRLENVQHKMFKGLE--SLKTLMLRSNRITCVGNDS 124
Query 294 FAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
F L + L N I + + L ++ LNL
Sbjct 125 FIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNL 160
>2v70_C C SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Length=220
Score = 54.3 bits (129), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 46/202 (23%), Positives = 82/202 (41%), Gaps = 49/202 (24%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC DCS+ KL ++P+ +P L L +N+ L A +
Sbjct 8 KCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFK------------- 54
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
KLP L+ +N +N+++ + + F + + E+ L SN ++ +++ F
Sbjct 55 ----------KLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKG- 103
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
LE+L+ L+L +N+I + ++ SS++ L L
Sbjct 104 -----------------------LESLKTLMLRSNRITCVGNDSF--IGLSSVRLLSLYD 138
Query 207 NQIKEFSPGCFHAIGRLFGLFL 228
NQI +PG F + L L L
Sbjct 139 NQITTVAPGAFDTLHSLSTLNL 160
Score = 43.9 bits (102), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 45/189 (24%), Positives = 75/189 (40%), Gaps = 40/189 (21%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKL-EILDLQHNNLARLWKHANPGGPIYFLKG 560
F+ L L ++ SNN I +I + EG + EIL
Sbjct 53 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEIL------------------------- 87
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L SN + + ++FK L LK + L N + + F S++ L+L N
Sbjct 88 --------LTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDN 139
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTP 680
IT+V F +L+ L++ NPF+C C +AW W+ + ++ + C P
Sbjct 140 QITTVAPGAFD-TLHSLSTLNLLANPFNCNC-YLAWLGEWLRKKRI----VTGNPRCQKP 193
Query 681 PHYHGFPVR 689
P++
Sbjct 194 YFLKEIPIQ 202
Score = 35.0 bits (79), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 39/156 (25%), Positives = 62/156 (40%), Gaps = 32/156 (21%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L+NN+ L E IF L+K+ S+N+I + G F
Sbjct 36 ELRLNNNEFTVL--EATGIFKKLPQLRKINFSNNKITDIEEGAFEGA------------- 80
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
+ + + L++++L + F GL+ +L L L N + VGNDS
Sbjct 81 --------------SGVNEILLTSNRLENVQHKMFKGLE--SLKTLMLRSNRITCVGNDS 124
Query 294 FAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
F L + L N I + + L ++ LNL
Sbjct 125 FIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNL 160
>2v70_A A SLIT HOMOLOG 2 PROTEIN N-PRODUCT
Length=220
Score = 54.3 bits (129), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 46/202 (23%), Positives = 82/202 (41%), Gaps = 49/202 (24%)
Query 27 KCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNT 86
KC DCS+ KL ++P+ +P L L +N+ L A +
Sbjct 8 KCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFK------------- 54
Query 87 ISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ 146
KLP L+ +N +N+++ + + F + + E+ L SN ++ +++ F
Sbjct 55 ----------KLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKG- 103
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
LE+L+ L+L +N+I + ++ SS++ L L
Sbjct 104 -----------------------LESLKTLMLRSNRITCVGNDSF--IGLSSVRLLSLYD 138
Query 207 NQIKEFSPGCFHAIGRLFGLFL 228
NQI +PG F + L L L
Sbjct 139 NQITTVAPGAFDTLHSLSTLNL 160
Score = 43.9 bits (102), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 45/189 (24%), Positives = 75/189 (40%), Gaps = 40/189 (21%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKL-EILDLQHNNLARLWKHANPGGPIYFLKG 560
F+ L L ++ SNN I +I + EG + EIL
Sbjct 53 FKKLPQLRKINFSNNKITDIEEGAFEGASGVNEIL------------------------- 87
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L SN + + ++FK L LK + L N + + F S++ L+L N
Sbjct 88 --------LTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDN 139
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTP 680
IT+V F +L+ L++ NPF+C C +AW W+ + ++ + C P
Sbjct 140 QITTVAPGAFD-TLHSLSTLNLLANPFNCNC-YLAWLGEWLRKKRI----VTGNPRCQKP 193
Query 681 PHYHGFPVR 689
P++
Sbjct 194 YFLKEIPIQ 202
Score = 35.0 bits (79), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 39/156 (25%), Positives = 62/156 (40%), Gaps = 32/156 (21%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L+NN+ L E IF L+K+ S+N+I + G F
Sbjct 36 ELRLNNNEFTVL--EATGIFKKLPQLRKINFSNNKITDIEEGAFEGA------------- 80
Query 234 GPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDS 293
+ + + L++++L + F GL+ +L L L N + VGNDS
Sbjct 81 --------------SGVNEILLTSNRLENVQHKMFKGLE--SLKTLMLRSNRITCVGNDS 124
Query 294 FAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL 329
F L + L N I + + L ++ LNL
Sbjct 125 FIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNL 160
>4v2e_A A FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 3
Length=331
Score = 55.5 bits (132), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 81/311 (26%), Positives = 133/311 (43%), Gaps = 40/311 (13%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLP-AANFTRYSQLTSLD 81
S + C C+ LT +P +P + T L L +NQ+ + ++ ++ +
Sbjct 2 SCPSVCRCDAGFIYCNDRSLTSIPVGIPEDATTLYLQNNQINNVGIPSDLKNLLKVQRIY 61
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIK 139
+ N++ + L + +K L+LQ N + ++ + + L ELHL NS+ I+
Sbjct 62 LYHNSLDEFPTNLPK---YVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 118
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
F L L LS N LS+ G +E EL L +N+I + S L +SL
Sbjct 119 EGAFRDSNYLRLLFLSRNHLSTIPGGLPRTIE---ELRLDDNRISTISSPSLHGL--TSL 173
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
K+L L N LNN LG +K+ L N + LSL +
Sbjct 174 KRLVLDGN-------------------LLNNHGLG----DKVFFNLVN--LTELSLVRNS 208
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH 319
L+ + L T+L L L N++N V ++F++L QL + NN+ +L
Sbjct 209 LTAAP----VNLPGTSLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD 264
Query 320 GLFNVRYLNLK 330
L N+ L L+
Sbjct 265 DLDNITQLILR 275
Score = 51.2 bits (121), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 68/280 (24%), Positives = 122/280 (44%), Gaps = 44/280 (16%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L +N I I D+ S + +LE L L N + ++ +E ++ +Y + L L
Sbjct 81 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVS-AVSIEEGAFRDS------NYLRLLFL 133
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
+RN + +P P + LR L +N I+ I+ L GL
Sbjct 134 SRNHLSTIPG---------------GLPRTIEELR------LDDNRISTISSPSLHGLTS 172
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L+ L L N L + G ++F L +L L+L N PV + L+ +
Sbjct 173 LKRLVLDGN----LLNNHGLGDKVFF--NLVNLTELSLVRNSLTAAPVNLPGT--SLRKL 224
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTC 651
L N++N +P + F+ L L++ N ++++ + +F N+T+L +R NP+ C C
Sbjct 225 YLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD-DLDNITQLILRNNPWYCGC 283
Query 652 ESIAWFVNWINE--THTNIPELSSHYLCNTPPHYHGFPVR 689
+ + W +W+ N+ L +C P G ++
Sbjct 284 K-MKWVRDWLQSLPVKVNVRGL----MCQAPEKVRGMAIK 318
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 54/210 (26%), Positives = 88/210 (42%), Gaps = 31/210 (15%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L NN+ + DS + +P LE L+ N++ + G F R N R
Sbjct 81 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE--EGAF--RDSNYLRLLFLSRN 136
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
L+++P + +E L ++DN I I S GL +LK L L + + L +
Sbjct 137 HLSTIPG------GLPRTIEELRLDDNRISTISSPSLHGLTSLKRLVLDGNLLNNHGLGD 190
Query 399 ETF--------------------VSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDL 438
+ F V+L + L L L N I+++ +AFS+L L LD+
Sbjct 191 KVFFNLVNLTELSLVRNSLTAAPVNLPGTSLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 250
Query 439 GLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
N + G + L+NI ++ L N +
Sbjct 251 SNNNLSNLPQGI-FDDLDNITQLILRNNPW 279
Score = 42.0 bits (97), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 68/142 (48%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ +P LP I L L N++ + + + + L L + N ++ L ++ L
Sbjct 138 LSTIPGGLPRTIEELRLDDNRISTISSPSLHGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 197
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L+L N L+ T+L +L+L N I ++ N F + L LD+S+N L
Sbjct 198 NLTELSLVRNSLTAAPVNLPG--TSLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 255
Query 160 SSTKLGTQVQLENLQELLLSNN 181
S+ G L+N+ +L+L NN
Sbjct 256 SNLPQGIFDDLDNITQLILRNN 277
Score = 42.0 bits (97), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 57/221 (26%), Positives = 98/221 (44%), Gaps = 36/221 (16%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS-- 403
+D+F K ++ L++++N+I I + + + L+ L L ++ S ++ F
Sbjct 67 LDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSN 126
Query 404 -----------LAHSP------LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
L+ P + L L N+IS I S + L L+ L L N +
Sbjct 127 YLRLLFLSRNHLSTIPGGLPRTIEELRLDDNRISTISSPSLHGLTSLKRLVLDGNLLNNH 186
Query 447 LTGQE-WRGLENIFEIYLSYNKYLQLTRNSFALVP------SLQRLMLRRVALKNVDSSP 499
G + + L N+ E L L RNS P SL++L L+ + V P
Sbjct 187 GLGDKVFFNLVNLTE--------LSLVRNSLTAAPVNLPGTSLRKLYLQDNHINRV--PP 236
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+ F LR L LD+SNNN++N+ + + L+ + L L++N
Sbjct 237 NAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 277
>4v2e_B B FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 3
Length=331
Score = 55.5 bits (132), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 81/311 (26%), Positives = 133/311 (43%), Gaps = 40/311 (13%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLP-AANFTRYSQLTSLD 81
S + C C+ LT +P +P + T L L +NQ+ + ++ ++ +
Sbjct 2 SCPSVCRCDAGFIYCNDRSLTSIPVGIPEDATTLYLQNNQINNVGIPSDLKNLLKVQRIY 61
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIK 139
+ N++ + L + +K L+LQ N + ++ + + L ELHL NS+ I+
Sbjct 62 LYHNSLDEFPTNLPK---YVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 118
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
F L L LS N LS+ G +E EL L +N+I + S L +SL
Sbjct 119 EGAFRDSNYLRLLFLSRNHLSTIPGGLPRTIE---ELRLDDNRISTISSPSLHGL--TSL 173
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
K+L L N LNN LG +K+ L N + LSL +
Sbjct 174 KRLVLDGN-------------------LLNNHGLG----DKVFFNLVN--LTELSLVRNS 208
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH 319
L+ + L T+L L L N++N V ++F++L QL + NN+ +L
Sbjct 209 LTAAP----VNLPGTSLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD 264
Query 320 GLFNVRYLNLK 330
L N+ L L+
Sbjct 265 DLDNITQLILR 275
Score = 51.2 bits (121), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 68/280 (24%), Positives = 122/280 (44%), Gaps = 44/280 (16%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L +N I I D+ S + +LE L L N + ++ +E ++ +Y + L L
Sbjct 81 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVS-AVSIEEGAFRDS------NYLRLLFL 133
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
+RN + +P P + LR L +N I+ I+ L GL
Sbjct 134 SRNHLSTIPG---------------GLPRTIEELR------LDDNRISTISSPSLHGLTS 172
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L+ L L N L + G ++F L +L L+L N PV + L+ +
Sbjct 173 LKRLVLDGN----LLNNHGLGDKVFF--NLVNLTELSLVRNSLTAAPVNLPGT--SLRKL 224
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTC 651
L N++N +P + F+ L L++ N ++++ + +F N+T+L +R NP+ C C
Sbjct 225 YLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD-DLDNITQLILRNNPWYCGC 283
Query 652 ESIAWFVNWINE--THTNIPELSSHYLCNTPPHYHGFPVR 689
+ + W +W+ N+ L +C P G ++
Sbjct 284 K-MKWVRDWLQSLPVKVNVRGL----MCQAPEKVRGMAIK 318
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 54/210 (26%), Positives = 88/210 (42%), Gaps = 31/210 (15%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L NN+ + DS + +P LE L+ N++ + G F R N R
Sbjct 81 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE--EGAF--RDSNYLRLLFLSRN 136
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
L+++P + +E L ++DN I I S GL +LK L L + + L +
Sbjct 137 HLSTIPG------GLPRTIEELRLDDNRISTISSPSLHGLTSLKRLVLDGNLLNNHGLGD 190
Query 399 ETF--------------------VSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDL 438
+ F V+L + L L L N I+++ +AFS+L L LD+
Sbjct 191 KVFFNLVNLTELSLVRNSLTAAPVNLPGTSLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 250
Query 439 GLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
N + G + L+NI ++ L N +
Sbjct 251 SNNNLSNLPQGI-FDDLDNITQLILRNNPW 279
Score = 42.0 bits (97), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 68/142 (48%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ +P LP I L L N++ + + + + L L + N ++ L ++ L
Sbjct 138 LSTIPGGLPRTIEELRLDDNRISTISSPSLHGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 197
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L+L N L+ T+L +L+L N I ++ N F + L LD+S+N L
Sbjct 198 NLTELSLVRNSLTAAPVNLPG--TSLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 255
Query 160 SSTKLGTQVQLENLQELLLSNN 181
S+ G L+N+ +L+L NN
Sbjct 256 SNLPQGIFDDLDNITQLILRNN 277
Score = 42.0 bits (97), Expect = 0.020, Method: Compositional matrix adjust.
Identities = 57/221 (26%), Positives = 98/221 (44%), Gaps = 36/221 (16%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS-- 403
+D+F K ++ L++++N+I I + + + L+ L L ++ S ++ F
Sbjct 67 LDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSN 126
Query 404 -----------LAHSP------LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
L+ P + L L N+IS I S + L L+ L L N +
Sbjct 127 YLRLLFLSRNHLSTIPGGLPRTIEELRLDDNRISTISSPSLHGLTSLKRLVLDGNLLNNH 186
Query 447 LTGQE-WRGLENIFEIYLSYNKYLQLTRNSFALVP------SLQRLMLRRVALKNVDSSP 499
G + + L N+ E L L RNS P SL++L L+ + V P
Sbjct 187 GLGDKVFFNLVNLTE--------LSLVRNSLTAAPVNLPGTSLRKLYLQDNHINRV--PP 236
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+ F LR L LD+SNNN++N+ + + L+ + L L++N
Sbjct 237 NAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 277
>6tl8_A A Myeloid cell surface antigen CD33,Leucine-rich repeat
and fibronectin type-III domain-containing protein 4
Length=299
Score = 55.1 bits (131), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 80/165 (48%), Gaps = 12/165 (7%)
Query 445 QELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQP 504
Q L ++R + + ++ LS N ++ SF + SL+ L L L + SS S P
Sbjct 65 QALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRLVELGSS-SLRGP 123
Query 505 LRNLTILDLSNNNIANINDDMLEG-LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
+ NL L LS N + I + L+ LE LD+ +NNL ++ P + +
Sbjct 124 V-NLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQV--------PWAGIGSMPA 174
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTL-PASVFN 607
LH LNL+ N D +P VF L +L +DL N L TL P +F+
Sbjct 175 LHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPLFS 219
Score = 51.2 bits (121), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 49/164 (30%), Positives = 69/164 (42%), Gaps = 15/164 (9%)
Query 488 RRVALKNVDS-----SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
R V L+ D+ P F+ + L L LS N I I LE L L L N L
Sbjct 53 RTVELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRL 112
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFE-LKIIDLGLNNLNTL 601
L + L+G +L L L N I F D + L+ +D+ NNL +
Sbjct 113 VELGSSS--------LRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQV 164
Query 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
P + + +L +LNL NLI ++ VF L+ LD+ N
Sbjct 165 PWAGIGSMPALHTLNLDHNLIDALPPGVFA-QLSQLSRLDLTSN 207
Score = 48.5 bits (114), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 30/95 (32%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query 50 PTNITVLNLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQH 108
P N+ L L+ NQL R+ F + L LDV +N + ++ +P L LNL H
Sbjct 123 PVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVPWAGIGSMPALHTLNLDH 182
Query 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
N + L FA + L+ L L SN + + +P
Sbjct 183 NLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPL 217
Score = 43.9 bits (102), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 57/234 (24%), Positives = 84/234 (36%), Gaps = 26/234 (11%)
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
E+ L+ N L F + L L L R A+ + + F L +L L L N +
Sbjct 56 ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARS--FGDLESLRSLHLDGNRLV 113
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
+ L G L+ L L N L R+ P F L L L++ N ++P
Sbjct 114 ELGSSSLRGPVNLQHLILSGNQLGRI-------APGAFDDFLDSLEDLDVSYNNLRQVPW 166
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
+ L ++L N ++ LP VF L L+L N + ++ P F
Sbjct 167 AGIGSMPALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPD---PLFSXXXX 223
Query 640 ---------LDMRFNPFDCTCESIAWFVNWIN----ETHTNIPELSSHYLCNTP 680
L NP C CE + W ET + P L+ Y P
Sbjct 224 XXXXXXXXVLSFSGNPLHCNCE-LLWLRRLARPDDLETCASPPTLAGRYFWAVP 276
Score = 38.5 bits (88), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 46/146 (32%), Positives = 64/146 (44%), Gaps = 20/146 (14%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L++N IQAL + F N + L L LS N I F + L L L+ +L
Sbjct 56 ELRLADNFIQALGPPD---FRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRL 112
Query 234 GPSLTEKLCLELANTSIRN------LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN 287
+EL ++S+R L LS +QL + F +L LD+SYNNL
Sbjct 113 ---------VELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDF-LDSLEDLDVSYNNLR 162
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHL 313
V +P L L++N I L
Sbjct 163 QVPWAGIGSMPALHTLNLDHNLIDAL 188
Score = 38.5 bits (88), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 42/168 (25%), Positives = 78/168 (46%), Gaps = 6/168 (4%)
Query 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
L + DN I + F + L L+LS + ++ + +F L L L+L N+
Sbjct 56 ELRLADNFIQALGPPDFRNMTGLVDLTLSRN--AITRIGARSFGDLES--LRSLHLDGNR 111
Query 419 ISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFAL 478
+ ++ S + +L+ L L N++G+ G L+++ ++ +SYN Q+
Sbjct 112 LVELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVPWAGIGS 171
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
+P+L L L + + P F L L+ LDL++N +A + D L
Sbjct 172 MPALHTLNLDHNLIDAL--PPGVFAQLSQLSRLDLTSNRLATLAPDPL 217
>4xsq_B B variable lymphocyte receptor-like protein Bf66946
Length=203
Score = 53.5 bits (127), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 31/101 (31%), Positives = 51/101 (50%), Gaps = 3/101 (3%)
Query 24 STTKCTVS---HEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSL 80
S KCTVS V C + LT++P+D+P L L N + ++ + +F L +
Sbjct 4 SACKCTVSLYGEMVVACGGMGLTEIPEDIPHRAVYLVLKDNNITKITSYSFKGLRNLQGI 63
Query 81 DVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAF 121
D+ N I+ + + L L ++L NEL+ +S+K F F
Sbjct 64 DLSNNKINHISSAALRHLGHLDDIDLSRNELTSVSEKLFDF 104
Score = 44.3 bits (103), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/125 (27%), Positives = 53/125 (42%), Gaps = 9/125 (7%)
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
L L+ N +I FK L L+ IDL N +N + ++ + L ++L +N +TSV
Sbjct 39 LVLKDNNITKITSYSFKGLRNLQGIDLSNNKINHISSAALRHLGHLDDIDLSRNELTSVS 98
Query 627 KKVFGPAFRNLTELDMRF------NPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTP 680
+K+F + RF NP+ C C +AW + + H C TP
Sbjct 99 EKLFDFPISSAKAQGRRFFVYLANNPWGCDCR-MAWLAQELAGGSKTFGD--RHMECATP 155
Query 681 PHYHG 685
G
Sbjct 156 AALAG 160
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 28/85 (33%), Positives = 38/85 (45%), Gaps = 28/85 (33%)
Query 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
+L ++DN+I I S F GL NL+ + LSN NK
Sbjct 38 YLVLKDNNITKITSYSFKGLRNLQGIDLSN----------------------------NK 69
Query 419 ISKIESDAFSWLGHLEVLDLGLNEI 443
I+ I S A LGHL+ +DL NE+
Sbjct 70 INHISSAALRHLGHLDDIDLSRNEL 94
Score = 35.0 bits (79), Expect = 2.5, Method: Compositional matrix adjust.
Identities = 19/41 (46%), Positives = 25/41 (61%), Gaps = 0/41 (0%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
F+ LRNL +DLSNN I +I+ L L L+ +DL N L
Sbjct 54 FKGLRNLQGIDLSNNKINHISSAALRHLGHLDDIDLSRNEL 94
>6tl8_C C Myeloid cell surface antigen CD33,Leucine-rich repeat
and fibronectin type-III domain-containing protein 4
Length=299
Score = 54.7 bits (130), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 53/164 (32%), Positives = 79/164 (48%), Gaps = 12/164 (7%)
Query 445 QELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQP 504
Q L ++R + + ++ LS N ++ SF + SL+ L L L + SS S P
Sbjct 65 QALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRLVELGSS-SLRGP 123
Query 505 LRNLTILDLSNNNIANINDDMLEG-LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
+ NL L LS N + I + L+ LE LD+ +NNL ++ P + +
Sbjct 124 V-NLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQV--------PWAGIGSMPA 174
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTL-PASVF 606
LH LNL+ N D +P VF L +L +DL N L TL P +F
Sbjct 175 LHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPLF 218
Score = 51.2 bits (121), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 49/164 (30%), Positives = 69/164 (42%), Gaps = 15/164 (9%)
Query 488 RRVALKNVDS-----SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
R V L+ D+ P F+ + L L LS N I I LE L L L N L
Sbjct 53 RTVELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRL 112
Query 543 ARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFE-LKIIDLGLNNLNTL 601
L + L+G +L L L N I F D + L+ +D+ NNL +
Sbjct 113 VELGSSS--------LRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQV 164
Query 602 PASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
P + + +L +LNL NLI ++ VF L+ LD+ N
Sbjct 165 PWAGIGSMPALHTLNLDHNLIDALPPGVFA-QLSQLSRLDLTSN 207
Score = 48.5 bits (114), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 30/95 (32%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query 50 PTNITVLNLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQH 108
P N+ L L+ NQL R+ F + L LDV +N + ++ +P L LNL H
Sbjct 123 PVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVPWAGIGSMPALHTLNLDH 182
Query 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
N + L FA + L+ L L SN + + +P
Sbjct 183 NLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPL 217
Score = 43.9 bits (102), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 57/234 (24%), Positives = 84/234 (36%), Gaps = 26/234 (11%)
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
E+ L+ N L F + L L L R A+ + + F L +L L L N +
Sbjct 56 ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARS--FGDLESLRSLHLDGNRLV 113
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
+ L G L+ L L N L R+ P F L L L++ N ++P
Sbjct 114 ELGSSSLRGPVNLQHLILSGNQLGRI-------APGAFDDFLDSLEDLDVSYNNLRQVPW 166
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
+ L ++L N ++ LP VF L L+L N + ++ P F
Sbjct 167 AGIGSMPALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPD---PLFXXXXX 223
Query 640 ---------LDMRFNPFDCTCESIAWFVNWIN----ETHTNIPELSSHYLCNTP 680
L NP C CE + W ET + P L+ Y P
Sbjct 224 XXXXXXPLVLSFSGNPLHCNCE-LLWLRRLARPDDLETCASPPTLAGRYFWAVP 276
Score = 38.9 bits (89), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 46/146 (32%), Positives = 64/146 (44%), Gaps = 20/146 (14%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L++N IQAL + F N + L L LS N I F + L L L+ +L
Sbjct 56 ELRLADNFIQALGPPD---FRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRL 112
Query 234 GPSLTEKLCLELANTSIRN------LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN 287
+EL ++S+R L LS +QL + F +L LD+SYNNL
Sbjct 113 ---------VELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDF-LDSLEDLDVSYNNLR 162
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHL 313
V +P L L++N I L
Sbjct 163 QVPWAGIGSMPALHTLNLDHNLIDAL 188
Score = 38.5 bits (88), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 42/168 (25%), Positives = 78/168 (46%), Gaps = 6/168 (4%)
Query 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
L + DN I + F + L L+LS + ++ + +F L L L+L N+
Sbjct 56 ELRLADNFIQALGPPDFRNMTGLVDLTLSRN--AITRIGARSFGDLES--LRSLHLDGNR 111
Query 419 ISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFAL 478
+ ++ S + +L+ L L N++G+ G L+++ ++ +SYN Q+
Sbjct 112 LVELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDFLDSLEDLDVSYNNLRQVPWAGIGS 171
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
+P+L L L + + P F L L+ LDL++N +A + D L
Sbjct 172 MPALHTLNLDHNLIDAL--PPGVFAQLSQLSRLDLTSNRLATLAPDPL 217
>4yeb_B B Fibronectin leucine rich transmembrane protein 3
Length=370
Score = 55.5 bits (132), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 81/311 (26%), Positives = 133/311 (43%), Gaps = 40/311 (13%)
Query 23 SSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLP-AANFTRYSQLTSLD 81
S + C C+ LT +P +P + T L L +NQ+ + ++ ++ +
Sbjct 8 SCPSVCRCDAGFIYCNDRSLTSIPVGIPEDATTLYLQNNQINNVGIPSDLKNLLKVQRIY 67
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ--KIK 139
+ N++ + L + +K L+LQ N + ++ + + L ELHL NS+ I+
Sbjct 68 LYHNSLDEFPTNLPK---YVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE 124
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
F L L LS N LS+ G +E EL L +N+I + S L +SL
Sbjct 125 EGAFRDSNYLRLLFLSRNHLSTIPGGLPRTIE---ELRLDDNRISTISSPSLHGL--TSL 179
Query 200 KKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ 259
K+L L N LNN LG +K+ L N + LSL +
Sbjct 180 KRLVLDGN-------------------LLNNHGLG----DKVFFNLVN--LTELSLVRNS 214
Query 260 LSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLH 319
L+ + L T+L L L N++N V ++F++L QL + NN+ +L
Sbjct 215 LTAAP----VNLPGTSLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD 270
Query 320 GLFNVRYLNLK 330
L N+ L L+
Sbjct 271 DLDNITQLILR 281
Score = 51.2 bits (121), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 68/280 (24%), Positives = 122/280 (44%), Gaps = 44/280 (16%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQL 471
L+L +N I I D+ S + +LE L L N + ++ +E ++ +Y + L L
Sbjct 87 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVS-AVSIEEGAFRDS------NYLRLLFL 139
Query 472 TRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEK 531
+RN + +P P + LR L +N I+ I+ L GL
Sbjct 140 SRNHLSTIPG---------------GLPRTIEELR------LDDNRISTISSPSLHGLTS 178
Query 532 LEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKII 591
L+ L L N L + G ++F L +L L+L N PV + L+ +
Sbjct 179 LKRLVLDGN----LLNNHGLGDKVFF--NLVNLTELSLVRNSLTAAPVNLPGT--SLRKL 230
Query 592 DLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTC 651
L N++N +P + F+ L L++ N ++++ + +F N+T+L +R NP+ C C
Sbjct 231 YLQDNHINRVPPNAFSYLRQLYRLDMSNNNLSNLPQGIFD-DLDNITQLILRNNPWYCGC 289
Query 652 ESIAWFVNWINE--THTNIPELSSHYLCNTPPHYHGFPVR 689
+ + W +W+ N+ L +C P G ++
Sbjct 290 K-MKWVRDWLQSLPVKVNVRGL----MCQAPEKVRGMAIK 324
Score = 43.9 bits (102), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 54/210 (26%), Positives = 88/210 (42%), Gaps = 31/210 (15%)
Query 279 LDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI 338
L L NN+ + DS + +P LE L+ N++ + G F R N R
Sbjct 87 LHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIE--EGAF--RDSNYLRLLFLSRN 142
Query 339 SLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTN 398
L+++P + +E L ++DN I I S GL +LK L L + + L +
Sbjct 143 HLSTIPG------GLPRTIEELRLDDNRISTISSPSLHGLTSLKRLVLDGNLLNNHGLGD 196
Query 399 ETF--------------------VSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDL 438
+ F V+L + L L L N I+++ +AFS+L L LD+
Sbjct 197 KVFFNLVNLTELSLVRNSLTAAPVNLPGTSLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 256
Query 439 GLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
N + G + L+NI ++ L N +
Sbjct 257 SNNNLSNLPQGI-FDDLDNITQLILRNNPW 285
Score = 42.0 bits (97), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 40/142 (28%), Positives = 68/142 (48%), Gaps = 4/142 (3%)
Query 42 LTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK--LEPELCQKLP 99
L+ +P LP I L L N++ + + + + L L + N ++ L ++ L
Sbjct 144 LSTIPGGLPRTIEELRLDDNRISTISSPSLHGLTSLKRLVLDGNLLNNHGLGDKVFFNLV 203
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
L L+L N L+ T+L +L+L N I ++ N F + L LD+S+N L
Sbjct 204 NLTELSLVRNSLTAAPVNLPG--TSLRKLYLQDNHINRVPPNAFSYLRQLYRLDMSNNNL 261
Query 160 SSTKLGTQVQLENLQELLLSNN 181
S+ G L+N+ +L+L NN
Sbjct 262 SNLPQGIFDDLDNITQLILRNN 283
Score = 42.0 bits (97), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 57/221 (26%), Positives = 98/221 (44%), Gaps = 36/221 (16%)
Query 346 IDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS-- 403
+D+F K ++ L++++N+I I + + + L+ L L ++ S ++ F
Sbjct 73 LDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSN 132
Query 404 -----------LAHSP------LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQE 446
L+ P + L L N+IS I S + L L+ L L N +
Sbjct 133 YLRLLFLSRNHLSTIPGGLPRTIEELRLDDNRISTISSPSLHGLTSLKRLVLDGNLLNNH 192
Query 447 LTGQE-WRGLENIFEIYLSYNKYLQLTRNSFALVP------SLQRLMLRRVALKNVDSSP 499
G + + L N+ E L L RNS P SL++L L+ + V P
Sbjct 193 GLGDKVFFNLVNLTE--------LSLVRNSLTAAPVNLPGTSLRKLYLQDNHINRV--PP 242
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+ F LR L LD+SNNN++N+ + + L+ + L L++N
Sbjct 243 NAFSYLRQLYRLDMSNNNLSNLPQGIFDDLDNITQLILRNN 283
>4xsq_A A variable lymphocyte receptor-like protein Bf66946
Length=203
Score = 53.5 bits (127), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 31/101 (31%), Positives = 51/101 (50%), Gaps = 3/101 (3%)
Query 24 STTKCTVS---HEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSL 80
S KCTVS V C + LT++P+D+P L L N + ++ + +F L +
Sbjct 4 SACKCTVSLYGEMVVACGGMGLTEIPEDIPHRAVYLVLKDNNITKITSYSFKGLRNLQGI 63
Query 81 DVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAF 121
D+ N I+ + + L L ++L NEL+ +S+K F F
Sbjct 64 DLSNNKINHISSAALRHLGHLDDIDLSRNELTSVSEKLFDF 104
Score = 44.3 bits (103), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 34/125 (27%), Positives = 53/125 (42%), Gaps = 9/125 (7%)
Query 567 LNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVE 626
L L+ N +I FK L L+ IDL N +N + ++ + L ++L +N +TSV
Sbjct 39 LVLKDNNITKITSYSFKGLRNLQGIDLSNNKINHISSAALRHLGHLDDIDLSRNELTSVS 98
Query 627 KKVFGPAFRNLTELDMRF------NPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTP 680
+K+F + RF NP+ C C +AW + + H C TP
Sbjct 99 EKLFDFPISSAKAQGRRFFVYLANNPWGCDCR-MAWLAQELAGGSKTFGD--RHMECATP 155
Query 681 PHYHG 685
G
Sbjct 156 AALAG 160
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 28/85 (33%), Positives = 38/85 (45%), Gaps = 28/85 (33%)
Query 359 HLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNK 418
+L ++DN+I I S F GL NL+ + LSN NK
Sbjct 38 YLVLKDNNITKITSYSFKGLRNLQGIDLSN----------------------------NK 69
Query 419 ISKIESDAFSWLGHLEVLDLGLNEI 443
I+ I S A LGHL+ +DL NE+
Sbjct 70 INHISSAALRHLGHLDDIDLSRNEL 94
Score = 35.0 bits (79), Expect = 2.4, Method: Compositional matrix adjust.
Identities = 19/41 (46%), Positives = 25/41 (61%), Gaps = 0/41 (0%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNL 542
F+ LRNL +DLSNN I +I+ L L L+ +DL N L
Sbjct 54 FKGLRNLQGIDLSNNKINHISSAALRHLGHLDDIDLSRNEL 94
>3a7c_A A Toll-like receptor 2, Variable lymphocyte receptor B
Length=580
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 131/558 (23%), Positives = 226/558 (41%), Gaps = 107/558 (19%)
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+LDLS N ++ G NLQ L+L +++I ++ + ++ SL+ L+LS N +
Sbjct 56 SLDLSFNKITYIGHGDLRACANLQVLILKSSRINTIEGDAF--YSLGSLEHLDLSDNHLS 113
Query 211 EFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNLSLSNSQ-LSTTSNTTF 268
S F G L L N+ P T + N T+++ L + N + S F
Sbjct 114 SLSSSWF---GPLSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDF 170
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
GL T+L L++ +L + S + + + L + L L +VRYL
Sbjct 171 AGL--TSLNELEIKALSLRNYQSQSLKSIRDIHHLTLHLSESAFLLEIFADILSSVRYLE 228
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
L R + LP +D+ S +K F G +
Sbjct 229 L-RDTNLARFQFSPLP-VDEVS-----------------SPMKKLAFRGSV--------- 260
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI-----------ESDAFSWLGHLEVLD 437
LT+E+F L +IL L++ + ESD S LG +E +
Sbjct 261 -------LTDESFNELLKLLRYILELSEVEFDDCTLNGLGDFNPSESDVVSELGKVETVT 313
Query 438 L------------GLNEIGQELTGQEWRGLEN--IFEIYLSYNKYL-------------- 469
+ L+ + L + +EN +F + S++++L
Sbjct 314 IRRLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMV 373
Query 470 -QLTRNSF--ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
+ +NS PSLQ L+L + L+++ + L+NLT LD+S N + D
Sbjct 374 EEYLKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPMPDSC- 432
Query 527 EGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLF 586
+ EK+ L+L + R+ K P L +L++ +N D +F L
Sbjct 433 QWPEKMRFLNLSSTGI-RVVKTCIP----------QTLEVLDVSNNNLDSF--SLF--LP 477
Query 587 ELKIIDLGLNNLNTLP-ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L+ + + N L TLP AS+F + +K + N + SV +F +L ++ + N
Sbjct 478 RLQELYISRNKLKTLPDASLFPVLLVMK---IASNQLKSVPDGIFD-RLTSLQKIWLHTN 533
Query 646 PFDCTCESIAWFVNWINE 663
P+DC+C I + W+N+
Sbjct 534 PWDCSCPRIDYLSRWLNK 551
>3a79_A A Toll-like receptor 2, Variable lymphocyte receptor B
Length=580
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 131/558 (23%), Positives = 226/558 (41%), Gaps = 107/558 (19%)
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+LDLS N ++ G NLQ L+L +++I ++ + ++ SL+ L+LS N +
Sbjct 56 SLDLSFNKITYIGHGDLRACANLQVLILKSSRINTIEGDAF--YSLGSLEHLDLSDNHLS 113
Query 211 EFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNLSLSNSQ-LSTTSNTTF 268
S F G L L N+ P T + N T+++ L + N + S F
Sbjct 114 SLSSSWF---GPLSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDF 170
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
GL T+L L++ +L + S + + + L + L L +VRYL
Sbjct 171 AGL--TSLNELEIKALSLRNYQSQSLKSIRDIHHLTLHLSESAFLLEIFADILSSVRYLE 228
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
L R + LP +D+ S +K F G +
Sbjct 229 L-RDTNLARFQFSPLP-VDEVS-----------------SPMKKLAFRGSV--------- 260
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI-----------ESDAFSWLGHLEVLD 437
LT+E+F L +IL L++ + ESD S LG +E +
Sbjct 261 -------LTDESFNELLKLLRYILELSEVEFDDCTLNGLGDFNPSESDVVSELGKVETVT 313
Query 438 L------------GLNEIGQELTGQEWRGLEN--IFEIYLSYNKYL-------------- 469
+ L+ + L + +EN +F + S++++L
Sbjct 314 IRRLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMV 373
Query 470 -QLTRNSF--ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
+ +NS PSLQ L+L + L+++ + L+NLT LD+S N + D
Sbjct 374 EEYLKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPMPDSC- 432
Query 527 EGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLF 586
+ EK+ L+L + R+ K P L +L++ +N D +F L
Sbjct 433 QWPEKMRFLNLSSTGI-RVVKTCIP----------QTLEVLDVSNNNLDSF--SLF--LP 477
Query 587 ELKIIDLGLNNLNTLP-ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L+ + + N L TLP AS+F + +K + N + SV +F +L ++ + N
Sbjct 478 RLQELYISRNKLKTLPDASLFPVLLVMK---IASNQLKSVPDGIFD-RLTSLQKIWLHTN 533
Query 646 PFDCTCESIAWFVNWINE 663
P+DC+C I + W+N+
Sbjct 534 PWDCSCPRIDYLSRWLNK 551
>3a7b_A A Toll-like receptor 2, Variable lymphocyte receptor B
Length=580
Score = 55.1 bits (131), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 131/558 (23%), Positives = 226/558 (41%), Gaps = 107/558 (19%)
Query 151 TLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
+LDLS N ++ G NLQ L+L +++I ++ + ++ SL+ L+LS N +
Sbjct 56 SLDLSFNKITYIGHGDLRACANLQVLILKSSRINTIEGDAF--YSLGSLEHLDLSDNHLS 113
Query 211 EFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNLSLSNSQ-LSTTSNTTF 268
S F G L L N+ P T + N T+++ L + N + S F
Sbjct 114 SLSSSWF---GPLSSLKYLNLMGNPYQTLGVTSLFPNLTNLQTLRIGNVETFSEIRRIDF 170
Query 269 LGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLN 328
GL T+L L++ +L + S + + + L + L L +VRYL
Sbjct 171 AGL--TSLNELEIKALSLRNYQSQSLKSIRDIHHLTLHLSESAFLLEIFADILSSVRYLE 228
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSN 388
L R + LP +D+ S +K F G +
Sbjct 229 L-RDTNLARFQFSPLP-VDEVS-----------------SPMKKLAFRGSV--------- 260
Query 389 SFTSLRTLTNETFVSLAHSPLHILNLTKNKISKI-----------ESDAFSWLGHLEVLD 437
LT+E+F L +IL L++ + ESD S LG +E +
Sbjct 261 -------LTDESFNELLKLLRYILELSEVEFDDCTLNGLGDFNPSESDVVSELGKVETVT 313
Query 438 L------------GLNEIGQELTGQEWRGLEN--IFEIYLSYNKYL-------------- 469
+ L+ + L + +EN +F + S++++L
Sbjct 314 IRRLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLKSLEFLDLSENLMV 373
Query 470 -QLTRNSF--ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
+ +NS PSLQ L+L + L+++ + L+NLT LD+S N + D
Sbjct 374 EEYLKNSACKGAWPSLQTLVLSQNHLRSMQKTGEILLTLKNLTSLDISRNTFHPMPDSC- 432
Query 527 EGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLF 586
+ EK+ L+L + R+ K P L +L++ +N D +F L
Sbjct 433 QWPEKMRFLNLSSTGI-RVVKTCIP----------QTLEVLDVSNNNLDSF--SLF--LP 477
Query 587 ELKIIDLGLNNLNTLP-ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
L+ + + N L TLP AS+F + +K + N + SV +F +L ++ + N
Sbjct 478 RLQELYISRNKLKTLPDASLFPVLLVMK---IASNQLKSVPDGIFD-RLTSLQKIWLHTN 533
Query 646 PFDCTCESIAWFVNWINE 663
P+DC+C I + W+N+
Sbjct 534 PWDCSCPRIDYLSRWLNK 551
>2xot_B B Amphoterin-induced protein 1
Length=361
Score = 54.3 bits (129), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 53/207 (26%), Positives = 92/207 (44%), Gaps = 35/207 (17%)
Query 498 SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF 557
S F P+ NL LDLS+N++ +++ + L+ LE+L L +N++ + ++A
Sbjct 80 SSEAFVPVPNLRYLDLSSNHLHTLDEFLFSDLQALEVLLLYNNHIVVVDRNA-------- 131
Query 558 LKGLSHLHILNLESNGFDEIPVEVFKD---LFELKIIDLGLNNLNTLPASVFNNQVSLKS 614
+ ++ L L L N PVE+ KD L +L ++DL N L LP +
Sbjct 132 FEDMAQLQKLYLSQNQISRFPVELIKDGNKLPKLMLLDLSSNKLKKLPLT---------- 181
Query 615 LNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSH 674
+LQK L V+ ++ + NP +C C+ F +W +++ +
Sbjct 182 -DLQK-LPAWVKNGLY-----------LHNNPLECDCKLYQLFSHWQYRQLSSVMDFQED 228
Query 675 YLCNTPPHYHG-FPVRLFDTSSCKDSA 700
C H F + F+ S K+SA
Sbjct 229 LYCMHSKKLHNIFSLDFFNCSEYKESA 255
Score = 48.5 bits (114), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 47/123 (38%), Positives = 61/123 (50%), Gaps = 4/123 (3%)
Query 92 PELCQKLP-MLKVLNLQHNELSQL-SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
P + Q LP +L+L HN LS+L ++ T TNL L L N + I + FV NL
Sbjct 31 PNVPQSLPSYTALLDLSHNNLSRLRAEWTPTRLTNLHSLLLSHNHLNFISSEAFVPVPNL 90
Query 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
LDLS N L + L+ L+ LLL NN I + + A L+KL LS NQI
Sbjct 91 RYLDLSSNHLHTLDEFLFSDLQALEVLLLYNNHIVVVDRNAFEDMA--QLQKLYLSQNQI 148
Query 210 KEF 212
F
Sbjct 149 SRF 151
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 34/97 (35%), Positives = 51/97 (53%), Gaps = 7/97 (7%)
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
+LDL HNNL+RL P L++LH L L N + I E F + L+ +DL
Sbjct 43 LLDLSHNNLSRLRAEWTP-------TRLTNLHSLLLSHNHLNFISSEAFVPVPNLRYLDL 95
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N+L+TL +F++ +L+ L L N I V++ F
Sbjct 96 SSNHLHTLDEFLFSDLQALEVLLLYNNHIVVVDRNAF 132
Score = 39.3 bits (90), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 45/172 (26%), Positives = 64/172 (37%), Gaps = 30/172 (17%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLP-------------------------TNITVL 56
S C + + CS +L VP LP TN+ L
Sbjct 10 VSCPANCLCASNILSCSKQQLPNVPQSLPSYTALLDLSHNNLSRLRAEWTPTRLTNLHSL 69
Query 57 NLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSD 116
L+HN L + + F L LD+ N + L+ L L L+VL L +N + +
Sbjct 70 LLSHNHLNFISSEAFVPVPNLRYLDLSSNHLHTLDEFLFSDLQALEVLLLYNNHIVVVDR 129
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN----LITLDLSHNGLSSTKL 164
F L +L+L N I + +K N L+ LDLS N L L
Sbjct 130 NAFEDMAQLQKLYLSQNQISRFPVE-LIKDGNKLPKLMLLDLSSNKLKKLPL 180
Score = 37.0 bits (84), Expect = 0.98, Method: Compositional matrix adjust.
Identities = 35/115 (30%), Positives = 56/115 (49%), Gaps = 16/115 (14%)
Query 277 TMLDLSYNNLNVVGNDSFAWLP----QLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS 332
+LDLS+NNL+ + + W P L L +N++ + S + + N+RYL+L
Sbjct 42 ALLDLSHNNLSRLRAE---WTPTRLTNLHSLLLSHNHLNFISSEAFVPVPNLRYLDL--- 95
Query 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
S L +D+F F L+ LE L + +N I + N F + L+ L LS
Sbjct 96 ------SSNHLHTLDEFLFSDLQALEVLLLYNNHIVVVDRNAFEDMAQLQKLYLS 144
Score = 33.9 bits (76), Expect = 8.5, Method: Compositional matrix adjust.
Identities = 50/190 (26%), Positives = 89/190 (47%), Gaps = 39/190 (21%)
Query 360 LNMEDNDIPGIKSNM--FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
L+ +P + ++ +T L++L + N+ + LR T ++ HS L L+ N
Sbjct 23 LSCSKQQLPNVPQSLPSYTALLDLSH----NNLSRLRAEWTPTRLTNLHSLL----LSHN 74
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIG--QELTGQEWRGLENIFEIYLSYNKYLQLT-RN 474
++ I S+AF + +L LDL N + E + + L E+ L YN ++ + RN
Sbjct 75 HLNFISSEAFVPVPNLRYLDLSSNHLHTLDEFLFSDLQAL----EVLLLYNNHIVVVDRN 130
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRN------LTILDLSNNNIANINDDMLEG 528
+F + LQ+L L + + S P + +++ L +LDLS+N
Sbjct 131 AFEDMAQLQKLYLSQNQI-----SRFPVELIKDGNKLPKLMLLDLSSNK----------- 174
Query 529 LEKLEILDLQ 538
L+KL + DLQ
Sbjct 175 LKKLPLTDLQ 184
>1w8a_A A SLIT PROTEIN
Length=192
Score = 52.4 bits (124), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 44/154 (29%), Positives = 68/154 (44%), Gaps = 23/154 (15%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C DC+ L ++P D+P + T L L N+L R+ S D F
Sbjct 6 CHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRI------------SSDGLFG-- 51
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
+LP L L L+ N+L+ + F +++ EL L N I++I N F+
Sbjct 52 ---------RLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEISNKMFLGLH 102
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNN 181
L TL+L N +S G+ L +L L L++N
Sbjct 103 QLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASN 136
Score = 48.5 bits (114), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 47/165 (28%), Positives = 71/165 (43%), Gaps = 36/165 (22%)
Query 504 PLRNLTILDLSNNNIANINDDMLEG-LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLS 562
PL +L L++N + I+ D L G L L L+L+ N L + +A +G S
Sbjct 28 PLHTTELL-LNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNA--------FEGAS 78
Query 563 HLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLI 622
H+ L L N EI ++F L +LK ++L N ++ + F + SL SLNL
Sbjct 79 HIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLAS--- 135
Query 623 TSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTN 667
NPF+C C +AWF W+ + N
Sbjct 136 ----------------------NPFNCNCH-LAWFAEWLRKKSLN 157
Score = 36.2 bits (82), Expect = 0.93, Method: Compositional matrix adjust.
Identities = 29/94 (31%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Query 348 DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHS 407
D F L L L ++ N + GI+ N F G +++ L L + ++ ++N+ F+ L
Sbjct 47 DGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGEN--KIKEISNKMFLGLHQ- 103
Query 408 PLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LNL N+IS + +F L L L+L N
Sbjct 104 -LKTLNLYDNQISCVMPGSFEHLNSLTSLNLASN 136
Score = 35.0 bits (79), Expect = 1.9, Method: Compositional matrix adjust.
Identities = 29/94 (31%), Positives = 49/94 (52%), Gaps = 3/94 (3%)
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWR 453
R ++ F L H L L L +N+++ IE +AF H++ L LG N+I +E++ + +
Sbjct 43 RISSDGLFGRLPH--LVKLELKRNQLTGIEPNAFEGASHIQELQLGENKI-KEISNKMFL 99
Query 454 GLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
GL + + L N+ + SF + SL L L
Sbjct 100 GLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNL 133
Score = 35.0 bits (79), Expect = 2.2, Method: Compositional matrix adjust.
Identities = 32/104 (31%), Positives = 49/104 (47%), Gaps = 3/104 (3%)
Query 126 TELHLMSNSIQKIKNNP-FVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQ 184
TEL L N + +I ++ F + +L+ L+L N L+ + ++QEL L NKI+
Sbjct 32 TELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIK 91
Query 185 ALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+ ++ LK L L NQI PG F + L L L
Sbjct 92 EISNKMF--LGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNL 133
>4u06_A A LIC10831
Length=348
Score = 53.9 bits (128), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 79/245 (32%), Positives = 119/245 (49%), Gaps = 20/245 (8%)
Query 50 PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHN 109
P + VL+L+ +L+ LP + L L + +N ++ L P+ ++L L++L L+ N
Sbjct 12 PLEVRVLDLSRQELKTLPIE-IGKLKNLQRLYLHYNQLTVL-PQEIEQLKNLQLLYLRSN 69
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
L+ L K NL L L SN + + + KNL L L N L++ + Q
Sbjct 70 RLTTLP-KEIEQLKNLQVLDLGSNQLTVLPQE-IGQLKNLQLLYLHSNRLTTLSKDIE-Q 126
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L+NL+ L LSNN++ L +E I +LK L LS NQ F P + L LFLN
Sbjct 127 LQNLKSLDLSNNQLTTLPNE---IEQLKNLKSLYLSENQFATF-PKEIGQLQNLKVLFLN 182
Query 230 NVQLG--PSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN 287
N Q+ P+ KL ++ L LS++QL T + NL LDLSYN L
Sbjct 183 NNQITILPNEIAKL------KKLQYLYLSDNQLITLPKEIE---QLKNLQTLDLSYNQLM 233
Query 288 VVGND 292
++ +
Sbjct 234 ILPKE 238
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 109/380 (29%), Positives = 166/380 (44%), Gaps = 63/380 (17%)
Query 249 SIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
+R L LS +L T +G K NL L L YN L V+ + L L+ +L N
Sbjct 14 EVRVLDLSRQELKTLP--IEIG-KLKNLQRLYLHYNQLTVLPQE-IEQLKNLQLLYLRSN 69
Query 309 NIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIP 368
+ L + L N++ L+L S L LP+ LK L+ L + N +
Sbjct 70 RLTTL-PKEIEQLKNLQVLDLG------SNQLTVLPQ----EIGQLKNLQLLYLHSNRLT 118
Query 369 GIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFS 428
+ ++ L NLK L LSN+ L TL NE L + L L L++N+ + +
Sbjct 119 TLSKDI-EQLQNLKSLDLSNN--QLTTLPNE-IEQLKN--LKSLYLSENQFATFPKE-IG 171
Query 429 WLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLR 488
L +L+VL L N+I + E L+ + +YLS N+ + L
Sbjct 172 QLQNLKVLFLNNNQIT--ILPNEIAKLKKLQYLYLSDNQLITL----------------- 212
Query 489 RVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKH 548
P + L+NL LDLS N + + ++ + LE L+ LDL++N L L K
Sbjct 213 ----------PKEIEQLKNLQTLDLSYNQLMILPKEVGQ-LENLQTLDLRNNQLKTLPKE 261
Query 549 ANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNN 608
++ L +L L L +N +P E+ K L L + L N L TLP +
Sbjct 262 ---------IEQLKNLQTLFLSNNQLTILPQEIGK-LKNLLWLSLVYNQLTTLPNEI-EQ 310
Query 609 QVSLKSLNLQKNLITSVEKK 628
+L++L L N +S EKK
Sbjct 311 LKNLQTLYLNNNQFSSQEKK 330
Score = 42.4 bits (98), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 75/235 (32%), Positives = 105/235 (45%), Gaps = 27/235 (11%)
Query 12 GGLLPFGMLCASSTTKCTVSHEVADCSHLK--------LTQVPDDLP--TNITVLNLTHN 61
G L +L S T+S ++ +LK LT +P+++ N+ L L+ N
Sbjct 102 GQLKNLQLLYLHSNRLTTLSKDIEQLQNLKSLDLSNNQLTTLPNEIEQLKNLKSLYLSEN 161
Query 62 QLRRLPAANFTRYSQLTSLDVGF---NTISKLEPELCQKLPMLKVLNLQHNELSQLSDKT 118
Q P QL +L V F N I+ L E+ KL L+ L L N+L L K
Sbjct 162 QFATFPKE----IGQLQNLKVLFLNNNQITILPNEIA-KLKKLQYLYLSDNQLITLP-KE 215
Query 119 FAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV-QLENLQELL 177
NL L L N + I + +NL TLDL +N L + L ++ QL+NLQ L
Sbjct 216 IEQLKNLQTLDLSYNQLM-ILPKEVGQLENLQTLDLRNNQLKT--LPKEIEQLKNLQTLF 272
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ 232
LSNN++ L E I +L L L NQ+ P + L L+LNN Q
Sbjct 273 LSNNQLTILPQE---IGKLKNLLWLSLVYNQLTTL-PNEIEQLKNLQTLYLNNNQ 323
Score = 39.3 bits (90), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 64/250 (26%), Positives = 106/250 (42%), Gaps = 41/250 (16%)
Query 432 HLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVA 491
+ VLDL E+ + E L+N+ +YL YN+ L + + +LQ L LR
Sbjct 14 EVRVLDLSRQEL--KTLPIEIGKLKNLQRLYLHYNQ-LTVLPQEIEQLKNLQLLYLRSNR 70
Query 492 LKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM----------------------LEGL 529
L + P + L+NL +LDL +N + + ++ +E L
Sbjct 71 LTTL---PKEIEQLKNLQVLDLGSNQLTVLPQEIGQLKNLQLLYLHSNRLTTLSKDIEQL 127
Query 530 EKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELK 589
+ L+ LDL +N L L I LK L L+ L N F P E+ + L LK
Sbjct 128 QNLKSLDLSNNQLTTL------PNEIEQLKNLKSLY---LSENQFATFPKEIGQ-LQNLK 177
Query 590 IIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDC 649
++ L N + LP + + L+ L L N + ++ K++ +NL LD+ +N
Sbjct 178 VLFLNNNQITILPNEIAKLK-KLQYLYLSDNQLITLPKEI--EQLKNLQTLDLSYNQLMI 234
Query 650 TCESIAWFVN 659
+ + N
Sbjct 235 LPKEVGQLEN 244
>5il7_B B Rab family protein
Length=447
Score = 54.3 bits (129), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 57/183 (31%), Positives = 91/183 (50%), Gaps = 16/183 (9%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
++T L+L+ NQ+ + A LT L + N IS + P + L L L L N++
Sbjct 180 SLTELSLSSNQITDI--APLASLKSLTELSLSSNQISDIAP--LESLKSLTELQLSRNQI 235
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
S ++ +LTEL L SN I I P K+L L LS N +S + L
Sbjct 236 SDIA--PLESLKSLTELQLSSNQITDIA--PLASLKSLTELQLSRNQIS--DIAPLESLN 289
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
+L +L L+ N+I + + + +SL +LELSSNQI + +P ++ L L+L++
Sbjct 290 SLSKLWLNGNQITDIAP----LASLNSLTELELSSNQITDIAP--LASLKSLSTLWLSSN 343
Query 232 QLG 234
Q+
Sbjct 344 QIS 346
Score = 43.1 bits (100), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 73/247 (30%), Positives = 111/247 (45%), Gaps = 35/247 (14%)
Query 345 KIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETFV 402
KI D + + LK L L + N I I L +L LSLS N+ + + L E+
Sbjct 124 KISDIAPLESLKSLTELQLSSNQITDIAP--LASLKSLTELSLSGNNISDIAPL--ESLK 179
Query 403 SLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY 462
SL L+L+ N+I+ I + L L L L N+I ++ E L+++ E+
Sbjct 180 SLTE-----LSLSSNQITDIA--PLASLKSLTELSLSSNQIS-DIAPLE--SLKSLTELQ 229
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
LS N+ + + SL L L + ++ +P L++LT L LS N I++I
Sbjct 230 LSRNQISDIA--PLESLKSLTELQLSSNQITDI----APLASLKSLTELQLSRNQISDI- 282
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEV 581
LE L N+L++LW + N I L L+ L L L SN +I P+
Sbjct 283 ----APLESL-------NSLSKLWLNGNQITDIAPLASLNSLTELELSSNQITDIAPLAS 331
Query 582 FKDLFEL 588
K L L
Sbjct 332 LKSLSTL 338
Score = 34.3 bits (77), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 45/147 (31%), Positives = 65/147 (44%), Gaps = 21/147 (14%)
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLK 559
SP L +L++L L N I +I L L N+L+ LW N I L+
Sbjct 85 SPLASLNSLSMLWLDRNQITDI-----APLASL-------NSLSMLWLFGNKISDIAPLE 132
Query 560 GLSHLHILNLESNGFDEI-PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQ 618
L L L L SN +I P+ K L EL L NN++ + + + SL L+L
Sbjct 133 SLKSLTELQLSSNQITDIAPLASLKSLTELS---LSGNNISDI--APLESLKSLTELSLS 187
Query 619 KNLITSVEKKVFGPAFRNLTELDMRFN 645
N IT + + ++LTEL + N
Sbjct 188 SNQITDIAPLA---SLKSLTELSLSSN 211
>5il7_A A Rab family protein
Length=447
Score = 54.3 bits (129), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 57/183 (31%), Positives = 91/183 (50%), Gaps = 16/183 (9%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
++T L+L+ NQ+ + A LT L + N IS + P + L L L L N++
Sbjct 180 SLTELSLSSNQITDI--APLASLKSLTELSLSSNQISDIAP--LESLKSLTELQLSRNQI 235
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
S ++ +LTEL L SN I I P K+L L LS N +S + L
Sbjct 236 SDIA--PLESLKSLTELQLSSNQITDIA--PLASLKSLTELQLSRNQIS--DIAPLESLN 289
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
+L +L L+ N+I + + + +SL +LELSSNQI + +P ++ L L+L++
Sbjct 290 SLSKLWLNGNQITDIAP----LASLNSLTELELSSNQITDIAP--LASLKSLSTLWLSSN 343
Query 232 QLG 234
Q+
Sbjct 344 QIS 346
Score = 43.1 bits (100), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 73/247 (30%), Positives = 111/247 (45%), Gaps = 35/247 (14%)
Query 345 KIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETFV 402
KI D + + LK L L + N I I L +L LSLS N+ + + L E+
Sbjct 124 KISDIAPLESLKSLTELQLSSNQITDIAP--LASLKSLTELSLSGNNISDIAPL--ESLK 179
Query 403 SLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY 462
SL L+L+ N+I+ I + L L L L N+I ++ E L+++ E+
Sbjct 180 SLTE-----LSLSSNQITDIA--PLASLKSLTELSLSSNQIS-DIAPLE--SLKSLTELQ 229
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
LS N+ + + SL L L + ++ +P L++LT L LS N I++I
Sbjct 230 LSRNQISDIA--PLESLKSLTELQLSSNQITDI----APLASLKSLTELQLSRNQISDI- 282
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEV 581
LE L N+L++LW + N I L L+ L L L SN +I P+
Sbjct 283 ----APLESL-------NSLSKLWLNGNQITDIAPLASLNSLTELELSSNQITDIAPLAS 331
Query 582 FKDLFEL 588
K L L
Sbjct 332 LKSLSTL 338
Score = 34.3 bits (77), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 45/147 (31%), Positives = 65/147 (44%), Gaps = 21/147 (14%)
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLK 559
SP L +L++L L N I +I L L N+L+ LW N I L+
Sbjct 85 SPLASLNSLSMLWLDRNQITDI-----APLASL-------NSLSMLWLFGNKISDIAPLE 132
Query 560 GLSHLHILNLESNGFDEI-PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQ 618
L L L L SN +I P+ K L EL L NN++ + + + SL L+L
Sbjct 133 SLKSLTELQLSSNQITDIAPLASLKSLTELS---LSGNNISDI--APLESLKSLTELSLS 187
Query 619 KNLITSVEKKVFGPAFRNLTELDMRFN 645
N IT + + ++LTEL + N
Sbjct 188 SNQITDIAPLA---SLKSLTELSLSSN 211
>6tl8_D D Myeloid cell surface antigen CD33,Leucine-rich repeat
and fibronectin type-III domain-containing protein 4
Length=299
Score = 53.5 bits (127), Expect = 4e-06, Method: Composition-based stats.
Identities = 53/161 (33%), Positives = 76/161 (47%), Gaps = 17/161 (11%)
Query 445 QELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQP 504
Q L ++R + + ++ LS N ++ SF + SL+ L L L + SS S P
Sbjct 65 QALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRLVELGSS-SLRGP 123
Query 505 LRNLTILDLSNNNIANIN----DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG 560
+ NL L LS N + I DD L LE L D+ +NNL ++ P +
Sbjct 124 V-NLQHLILSGNQLGRIAPGAFDDFLXXLEDL---DVSYNNLRQV--------PWAGIGS 171
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTL 601
+ LH LNL+ N D +P VF L +L +DL N L TL
Sbjct 172 MPALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATL 212
Score = 51.6 bits (122), Expect = 2e-05, Method: Composition-based stats.
Identities = 52/172 (30%), Positives = 73/172 (42%), Gaps = 18/172 (10%)
Query 480 PSLQRLMLRRVALKNVDS-----SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
P++ R R V L+ D+ P F+ + L L LS N I I LE L
Sbjct 48 PNVDR---RTVELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARSFGDLESLRS 104
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKD-LFELKIIDL 593
L L N L L + L+G +L L L N I F D L L+ +D+
Sbjct 105 LHLDGNRLVELGSSS--------LRGPVNLQHLILSGNQLGRIAPGAFDDFLXXLEDLDV 156
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
NNL +P + + +L +LNL NLI ++ VF L+ LD+ N
Sbjct 157 SYNNLRQVPWAGIGSMPALHTLNLDHNLIDALPPGVFA-QLSQLSRLDLTSN 207
Score = 48.9 bits (115), Expect = 1e-04, Method: Composition-based stats.
Identities = 30/95 (32%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Query 50 PTNITVLNLTHNQLRRLPAANFTRY-SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQH 108
P N+ L L+ NQL R+ F + L LDV +N + ++ +P L LNL H
Sbjct 123 PVNLQHLILSGNQLGRIAPGAFDDFLXXLEDLDVSYNNLRQVPWAGIGSMPALHTLNLDH 182
Query 109 NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
N + L FA + L+ L L SN + + +P
Sbjct 183 NLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPL 217
Score = 43.1 bits (100), Expect = 0.008, Method: Composition-based stats.
Identities = 55/231 (24%), Positives = 82/231 (35%), Gaps = 20/231 (9%)
Query 460 EIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
E+ L+ N L F + L L L R A+ + + F L +L L L N +
Sbjct 56 ELRLADNFIQALGPPDFRNMTGLVDLTLSRNAITRIGARS--FGDLESLRSLHLDGNRLV 113
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
+ L G L+ L L N L R+ P F L L L++ N ++P
Sbjct 114 ELGSSSLRGPVNLQHLILSGNQLGRI-------APGAFDDFLXXLEDLDVSYNNLRQVPW 166
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
+ L ++L N ++ LP VF L L+L N + ++
Sbjct 167 AGIGSMPALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLATLAPDPLXXXXXXXXX 226
Query 640 ------LDMRFNPFDCTCESIAWFVNWIN----ETHTNIPELSSHYLCNTP 680
L NP C CE + W ET + P L+ Y P
Sbjct 227 XXXXXVLSFSGNPLHCNCE-LLWLRRLARPDDLETCASPPTLAGRYFWAVP 276
Score = 37.7 bits (86), Expect = 0.48, Method: Composition-based stats.
Identities = 46/146 (32%), Positives = 64/146 (44%), Gaps = 20/146 (14%)
Query 175 ELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
EL L++N IQAL + F N + L L LS N I F + L L L+ +L
Sbjct 56 ELRLADNFIQALGPPD---FRNMTGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRL 112
Query 234 GPSLTEKLCLELANTSIR------NLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLN 287
+EL ++S+R +L LS +QL + F L LD+SYNNL
Sbjct 113 ---------VELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDF-LXXLEDLDVSYNNLR 162
Query 288 VVGNDSFAWLPQLEYFFLEYNNIQHL 313
V +P L L++N I L
Sbjct 163 QVPWAGIGSMPALHTLNLDHNLIDAL 188
Score = 37.4 bits (85), Expect = 0.60, Method: Composition-based stats.
Identities = 42/167 (25%), Positives = 76/167 (46%), Gaps = 6/167 (4%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I + F + L L+LS + ++ + +F L L L+L N++
Sbjct 57 LRLADNFIQALGPPDFRNMTGLVDLTLSRN--AITRIGARSFGDL--ESLRSLHLDGNRL 112
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALV 479
++ S + +L+ L L N++G+ G L + ++ +SYN Q+ +
Sbjct 113 VELGSSSLRGPVNLQHLILSGNQLGRIAPGAFDDFLXXLEDLDVSYNNLRQVPWAGIGSM 172
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDML 526
P+L L L + + P F L L+ LDL++N +A + D L
Sbjct 173 PALHTLNLDHNLIDAL--PPGVFAQLSQLSRLDLTSNRLATLAPDPL 217
Score = 36.6 bits (83), Expect = 1.2, Method: Composition-based stats.
Identities = 46/171 (27%), Positives = 65/171 (38%), Gaps = 36/171 (21%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
T L L LS N + +G SF L L L+ N + L S SL G N+++L L
Sbjct 76 TGLVDLTLSRNAITRIGARSFGDLESLRSLHLDGNRLVELGSSSLRGPVNLQHLIL---- 131
Query 334 TKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
+ + + DDF L LE L++ S+ +L
Sbjct 132 SGNQLGRIAPGAFDDF----LXXLEDLDV--------------------------SYNNL 161
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIG 444
R + S+ LH LNL N I + F+ L L LDL N +
Sbjct 162 RQVPWAGIGSMP--ALHTLNLDHNLIDALPPGVFAQLSQLSRLDLTSNRLA 210
>6hlu_B B Rab family protein
Length=974
Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 57/182 (31%), Positives = 91/182 (50%), Gaps = 16/182 (9%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
++T L+L+ NQ+ + A LT L + N IS + P + L L L L N++
Sbjct 202 SLTELSLSSNQITDI--APLASLKSLTELSLSSNQISDIAP--LESLKSLTELQLSRNQI 257
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
S ++ +LTEL L SN I I P K+L L LS N +S + L
Sbjct 258 SDIA--PLESLKSLTELQLSSNQITDIA--PLASLKSLTELQLSRNQISD--IAPLESLN 311
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
+L +L L+ N+I + + + +SL +LELSSNQI + +P ++ L L+L++
Sbjct 312 SLSKLWLNGNQITDIAP----LASLNSLTELELSSNQITDIAP--LASLKSLSTLWLSSN 365
Query 232 QL 233
Q+
Sbjct 366 QI 367
Score = 42.4 bits (98), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 89/318 (28%), Positives = 138/318 (43%), Gaps = 47/318 (15%)
Query 345 KIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETFV 402
KI D + + LK L L + N I I L +L LSLS N+ + + L E+
Sbjct 146 KISDIAPLESLKSLTELQLSSNQITDIAP--LASLKSLTELSLSGNNISDIAPL--ESLK 201
Query 403 SLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY 462
SL L+L+ N+I+ I + L L L L N+I + + L
Sbjct 202 SLTE-----LSLSSNQITDIA--PLASLKSLTELSLSSNQISDIAPLESLKSLTE----- 249
Query 463 LSYNKYLQLTRNSFALVPSLQRLM-LRRVALK-NVDSSPSPFQPLRNLTILDLSNNNIAN 520
LQL+RN + + L+ L L + L N + +P L++LT L LS N I++
Sbjct 250 ------LQLSRNQISDIAPLESLKSLTELQLSSNQITDIAPLASLKSLTELQLSRNQISD 303
Query 521 INDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PV 579
I LE L N+L++LW + N I L L+ L L L SN +I P+
Sbjct 304 IAP--LESL----------NSLSKLWLNGNQITDIAPLASLNSLTELELSSNQITDIAPL 351
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
K L L + ++++ L + +++SL S N I+ + + +LT
Sbjct 352 ASLKSLSTLWLSSNQISDIAPLASLESLSELSLSS-----NQISDISPLA---SLNSLTG 403
Query 640 LDMRFNPFDCTCESIAWF 657
D+R NP E+I F
Sbjct 404 FDVRRNPIKRLPETITGF 421
Score = 33.9 bits (76), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 45/147 (31%), Positives = 65/147 (44%), Gaps = 21/147 (14%)
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLK 559
SP L +L++L L N I +I L L N+L+ LW N I L+
Sbjct 107 SPLASLNSLSMLWLDRNQITDIAP--LASL----------NSLSMLWLFGNKISDIAPLE 154
Query 560 GLSHLHILNLESNGFDEI-PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQ 618
L L L L SN +I P+ K L EL L NN++ + + + SL L+L
Sbjct 155 SLKSLTELQLSSNQITDIAPLASLKSLTELS---LSGNNISDI--APLESLKSLTELSLS 209
Query 619 KNLITSVEKKVFGPAFRNLTELDMRFN 645
N IT + + ++LTEL + N
Sbjct 210 SNQITDIAPLA---SLKSLTELSLSSN 233
>8r4c_B A Rab family protein
Length=1107
Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 57/183 (31%), Positives = 91/183 (50%), Gaps = 16/183 (9%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
++T L+L+ NQ+ + A LT L + N IS + P + L L L L N++
Sbjct 179 SLTELSLSSNQITDI--APLASLKSLTELSLSSNQISDIAP--LESLKSLTELQLSRNQI 234
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
S ++ +LTEL L SN I I P K+L L LS N +S + L
Sbjct 235 SDIA--PLESLKSLTELQLSSNQITDIA--PLASLKSLTELQLSRNQIS--DIAPLESLN 288
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
+L +L L+ N+I + + + +SL +LELSSNQI + +P ++ L L+L++
Sbjct 289 SLSKLWLNGNQITDIAP----LASLNSLTELELSSNQITDIAP--LASLKSLSTLWLSSN 342
Query 232 QLG 234
Q+
Sbjct 343 QIS 345
Score = 42.7 bits (99), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 73/247 (30%), Positives = 111/247 (45%), Gaps = 35/247 (14%)
Query 345 KIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETFV 402
KI D + + LK L L + N I I L +L LSLS N+ + + L E+
Sbjct 123 KISDIAPLESLKSLTELQLSSNQITDIAP--LASLKSLTELSLSGNNISDIAPL--ESLK 178
Query 403 SLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY 462
SL L+L+ N+I+ I + L L L L N+I ++ E L+++ E+
Sbjct 179 SLTE-----LSLSSNQITDIA--PLASLKSLTELSLSSNQIS-DIAPLE--SLKSLTELQ 228
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
LS N+ + + SL L L + ++ +P L++LT L LS N I++I
Sbjct 229 LSRNQISDIA--PLESLKSLTELQLSSNQITDI----APLASLKSLTELQLSRNQISDI- 281
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEV 581
LE L N+L++LW + N I L L+ L L L SN +I P+
Sbjct 282 ----APLESL-------NSLSKLWLNGNQITDIAPLASLNSLTELELSSNQITDIAPLAS 330
Query 582 FKDLFEL 588
K L L
Sbjct 331 LKSLSTL 337
Score = 34.3 bits (77), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 45/147 (31%), Positives = 65/147 (44%), Gaps = 21/147 (14%)
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLK 559
SP L +L++L L N I +I L L N+L+ LW N I L+
Sbjct 84 SPLASLNSLSMLWLDRNQITDI-----APLASL-------NSLSMLWLFGNKISDIAPLE 131
Query 560 GLSHLHILNLESNGFDEI-PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQ 618
L L L L SN +I P+ K L EL L NN++ + + + SL L+L
Sbjct 132 SLKSLTELQLSSNQITDIAPLASLKSLTELS---LSGNNISDI--APLESLKSLTELSLS 186
Query 619 KNLITSVEKKVFGPAFRNLTELDMRFN 645
N IT + + ++LTEL + N
Sbjct 187 SNQITDIAPLA---SLKSLTELSLSSN 210
>8r4b_A A Rab family protein
Length=1107
Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 57/183 (31%), Positives = 91/183 (50%), Gaps = 16/183 (9%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
++T L+L+ NQ+ + A LT L + N IS + P + L L L L N++
Sbjct 179 SLTELSLSSNQITDI--APLASLKSLTELSLSSNQISDIAP--LESLKSLTELQLSRNQI 234
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
S ++ +LTEL L SN I I P K+L L LS N +S + L
Sbjct 235 SDIA--PLESLKSLTELQLSSNQITDIA--PLASLKSLTELQLSRNQISD--IAPLESLN 288
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
+L +L L+ N+I + + + +SL +LELSSNQI + +P ++ L L+L++
Sbjct 289 SLSKLWLNGNQITDIAP----LASLNSLTELELSSNQITDIAP--LASLKSLSTLWLSSN 342
Query 232 QLG 234
Q+
Sbjct 343 QIS 345
Score = 42.0 bits (97), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 89/318 (28%), Positives = 138/318 (43%), Gaps = 47/318 (15%)
Query 345 KIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETFV 402
KI D + + LK L L + N I I L +L LSLS N+ + + L E+
Sbjct 123 KISDIAPLESLKSLTELQLSSNQITDIAP--LASLKSLTELSLSGNNISDIAPL--ESLK 178
Query 403 SLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY 462
SL L+L+ N+I+ I + L L L L N+I + + L
Sbjct 179 SLTE-----LSLSSNQITDIA--PLASLKSLTELSLSSNQISDIAPLESLKSLTE----- 226
Query 463 LSYNKYLQLTRNSFALVPSLQRLM-LRRVALK-NVDSSPSPFQPLRNLTILDLSNNNIAN 520
LQL+RN + + L+ L L + L N + +P L++LT L LS N I++
Sbjct 227 ------LQLSRNQISDIAPLESLKSLTELQLSSNQITDIAPLASLKSLTELQLSRNQISD 280
Query 521 INDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PV 579
I LE L N+L++LW + N I L L+ L L L SN +I P+
Sbjct 281 I-----APLESL-------NSLSKLWLNGNQITDIAPLASLNSLTELELSSNQITDIAPL 328
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
K L L + ++++ L + +++SL S N I+ + + +LT
Sbjct 329 ASLKSLSTLWLSSNQISDIAPLASLESLSELSLSS-----NQISDISPLA---SLNSLTG 380
Query 640 LDMRFNPFDCTCESIAWF 657
D+R NP E+I F
Sbjct 381 FDVRRNPIKRLPETITGF 398
Score = 33.9 bits (76), Expect = 9.4, Method: Compositional matrix adjust.
Identities = 45/147 (31%), Positives = 65/147 (44%), Gaps = 21/147 (14%)
Query 500 SPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLK 559
SP L +L++L L N I +I L L N+L+ LW N I L+
Sbjct 84 SPLASLNSLSMLWLDRNQITDI-----APLASL-------NSLSMLWLFGNKISDIAPLE 131
Query 560 GLSHLHILNLESNGFDEI-PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQ 618
L L L L SN +I P+ K L EL L NN++ + + + SL L+L
Sbjct 132 SLKSLTELQLSSNQITDIAPLASLKSLTELS---LSGNNISDI--APLESLKSLTELSLS 186
Query 619 KNLITSVEKKVFGPAFRNLTELDMRFN 645
N IT + + ++LTEL + N
Sbjct 187 SNQITDIAPLA---SLKSLTELSLSSN 210
>6m04_D D Volume-regulated anion channel subunit LRRC8D
Length=866
Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 86/317 (27%), Positives = 154/317 (49%), Gaps = 25/317 (8%)
Query 336 QSISLASLP-KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
Q + L P K++ +F +L+ L L+++ D+ I + ++ L NL+ L L + S
Sbjct 516 QELHLCHCPAKVEQTAFSFLRDHLRCLHVKFTDVAEIPAWVYL-LKNLRELYLIGNLNSE 574
Query 394 --RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
+ + E+ L H L IL++ N ++K+ S+ HL L + N+ + L
Sbjct 575 NNKMIGLESLRELRH--LKILHVKSN-LTKVPSNITDVAPHLTKLVIH-NDGTKLLVLNS 630
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
+ + N+ E+ L + ++ F+L +LQ L L+ ++ ++ S FQ L+ LT L
Sbjct 631 LKKMMNVAELELQNCELERIPHAIFSL-SNLQELDLKSNNIRTIEEIIS-FQHLKRLTCL 688
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLES 571
L +N I I + ++ LE L +N L L P+ L L L++
Sbjct 689 KLWHNKIVTIPPS-ITHVKNLESLYFSNNKLESL--------PVAVF-SLQKLRCLDVSY 738
Query 572 NGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
N IP+E+ L L+ + + N ++ LP +F + L++LNL +N ITS+ +KV
Sbjct 739 NNISMIPIEI-GLLQNLQHLHITGNKVDILPKQLFKC-IKLRTLNLGQNCITSLPEKV-- 794
Query 632 PAFRNLTELDMRFNPFD 648
LT+L+++ N FD
Sbjct 795 GQLSQLTQLELKGNCFD 811
Score = 41.6 bits (96), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 82/330 (25%), Positives = 151/330 (46%), Gaps = 42/330 (13%)
Query 33 EVADCSHLKLTQVPD-DLPTNITVL-NLTHNQLRRLPAA------NFTRYSQLTSLDVGF 84
++ D LKL +P+ +P I+ + NL L PA +F R L L V F
Sbjct 488 DLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLR-DHLRCLHVKF 546
Query 85 NTISKLEPEL-----CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
++++ + ++L ++ LN ++N++ L ++ +L LH+ SN + K+
Sbjct 547 TDVAEIPAWVYLLKNLRELYLIGNLNSENNKMIGL--ESLRELRHLKILHVKSN-LTKVP 603
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
+N +L L + ++G L + ++ N+ EL L N +++ + IF+ S+L
Sbjct 604 SNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELELQNCELERIPHA---IFSLSNL 660
Query 200 KKLELSSNQIKEFSPGC-FHAIGRLFGLFL---NNVQLGPSLTEKLCLELANTSIRNLSL 255
++L+L SN I+ F + RL L L V + PS+T LE +L
Sbjct 661 QELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE-------SLYF 713
Query 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFS 315
SN++L + F L LD+SYNN++++ + L L++ + N + +
Sbjct 714 SNNKLESLPVAVF---SLQKLRCLDVSYNNISMIPIE-IGLLQNLQHLHITGNKVD-ILP 768
Query 316 HSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L +R LNL ++ + SLP+
Sbjct 769 KQLFKCIKLRTLNLGQN------CITSLPE 792
>6m04_B B Volume-regulated anion channel subunit LRRC8D
Length=866
Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 86/317 (27%), Positives = 154/317 (49%), Gaps = 25/317 (8%)
Query 336 QSISLASLP-KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
Q + L P K++ +F +L+ L L+++ D+ I + ++ L NL+ L L + S
Sbjct 516 QELHLCHCPAKVEQTAFSFLRDHLRCLHVKFTDVAEIPAWVYL-LKNLRELYLIGNLNSE 574
Query 394 --RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
+ + E+ L H L IL++ N ++K+ S+ HL L + N+ + L
Sbjct 575 NNKMIGLESLRELRH--LKILHVKSN-LTKVPSNITDVAPHLTKLVIH-NDGTKLLVLNS 630
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
+ + N+ E+ L + ++ F+L +LQ L L+ ++ ++ S FQ L+ LT L
Sbjct 631 LKKMMNVAELELQNCELERIPHAIFSL-SNLQELDLKSNNIRTIEEIIS-FQHLKRLTCL 688
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLES 571
L +N I I + ++ LE L +N L L P+ L L L++
Sbjct 689 KLWHNKIVTIPPS-ITHVKNLESLYFSNNKLESL--------PVAVF-SLQKLRCLDVSY 738
Query 572 NGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
N IP+E+ L L+ + + N ++ LP +F + L++LNL +N ITS+ +KV
Sbjct 739 NNISMIPIEI-GLLQNLQHLHITGNKVDILPKQLFKC-IKLRTLNLGQNCITSLPEKV-- 794
Query 632 PAFRNLTELDMRFNPFD 648
LT+L+++ N FD
Sbjct 795 GQLSQLTQLELKGNCFD 811
Score = 41.6 bits (96), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 82/330 (25%), Positives = 151/330 (46%), Gaps = 42/330 (13%)
Query 33 EVADCSHLKLTQVPD-DLPTNITVL-NLTHNQLRRLPAA------NFTRYSQLTSLDVGF 84
++ D LKL +P+ +P I+ + NL L PA +F R L L V F
Sbjct 488 DLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLR-DHLRCLHVKF 546
Query 85 NTISKLEPEL-----CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
++++ + ++L ++ LN ++N++ L ++ +L LH+ SN + K+
Sbjct 547 TDVAEIPAWVYLLKNLRELYLIGNLNSENNKMIGL--ESLRELRHLKILHVKSN-LTKVP 603
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
+N +L L + ++G L + ++ N+ EL L N +++ + IF+ S+L
Sbjct 604 SNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELELQNCELERIPHA---IFSLSNL 660
Query 200 KKLELSSNQIKEFSPGC-FHAIGRLFGLFL---NNVQLGPSLTEKLCLELANTSIRNLSL 255
++L+L SN I+ F + RL L L V + PS+T LE +L
Sbjct 661 QELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE-------SLYF 713
Query 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFS 315
SN++L + F L LD+SYNN++++ + L L++ + N + +
Sbjct 714 SNNKLESLPVAVF---SLQKLRCLDVSYNNISMIPIE-IGLLQNLQHLHITGNKVD-ILP 768
Query 316 HSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L +R LNL ++ + SLP+
Sbjct 769 KQLFKCIKLRTLNLGQN------CITSLPE 792
>6m04_A A Volume-regulated anion channel subunit LRRC8D
Length=866
Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 86/317 (27%), Positives = 154/317 (49%), Gaps = 25/317 (8%)
Query 336 QSISLASLP-KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
Q + L P K++ +F +L+ L L+++ D+ I + ++ L NL+ L L + S
Sbjct 516 QELHLCHCPAKVEQTAFSFLRDHLRCLHVKFTDVAEIPAWVYL-LKNLRELYLIGNLNSE 574
Query 394 --RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
+ + E+ L H L IL++ N ++K+ S+ HL L + N+ + L
Sbjct 575 NNKMIGLESLRELRH--LKILHVKSN-LTKVPSNITDVAPHLTKLVIH-NDGTKLLVLNS 630
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
+ + N+ E+ L + ++ F+L +LQ L L+ ++ ++ S FQ L+ LT L
Sbjct 631 LKKMMNVAELELQNCELERIPHAIFSL-SNLQELDLKSNNIRTIEEIIS-FQHLKRLTCL 688
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLES 571
L +N I I + ++ LE L +N L L P+ L L L++
Sbjct 689 KLWHNKIVTIPPS-ITHVKNLESLYFSNNKLESL--------PVAVF-SLQKLRCLDVSY 738
Query 572 NGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
N IP+E+ L L+ + + N ++ LP +F + L++LNL +N ITS+ +KV
Sbjct 739 NNISMIPIEI-GLLQNLQHLHITGNKVDILPKQLFKC-IKLRTLNLGQNCITSLPEKV-- 794
Query 632 PAFRNLTELDMRFNPFD 648
LT+L+++ N FD
Sbjct 795 GQLSQLTQLELKGNCFD 811
Score = 41.6 bits (96), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 82/330 (25%), Positives = 151/330 (46%), Gaps = 42/330 (13%)
Query 33 EVADCSHLKLTQVPD-DLPTNITVL-NLTHNQLRRLPAA------NFTRYSQLTSLDVGF 84
++ D LKL +P+ +P I+ + NL L PA +F R L L V F
Sbjct 488 DLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLR-DHLRCLHVKF 546
Query 85 NTISKLEPEL-----CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
++++ + ++L ++ LN ++N++ L ++ +L LH+ SN + K+
Sbjct 547 TDVAEIPAWVYLLKNLRELYLIGNLNSENNKMIGL--ESLRELRHLKILHVKSN-LTKVP 603
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
+N +L L + ++G L + ++ N+ EL L N +++ + IF+ S+L
Sbjct 604 SNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELELQNCELERIPHA---IFSLSNL 660
Query 200 KKLELSSNQIKEFSPGC-FHAIGRLFGLFL---NNVQLGPSLTEKLCLELANTSIRNLSL 255
++L+L SN I+ F + RL L L V + PS+T LE +L
Sbjct 661 QELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE-------SLYF 713
Query 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFS 315
SN++L + F L LD+SYNN++++ + L L++ + N + +
Sbjct 714 SNNKLESLPVAVF---SLQKLRCLDVSYNNISMIPIE-IGLLQNLQHLHITGNKVD-ILP 768
Query 316 HSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L +R LNL ++ + SLP+
Sbjct 769 KQLFKCIKLRTLNLGQN------CITSLPE 792
>6m04_E E Volume-regulated anion channel subunit LRRC8D
Length=866
Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 86/317 (27%), Positives = 154/317 (49%), Gaps = 25/317 (8%)
Query 336 QSISLASLP-KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
Q + L P K++ +F +L+ L L+++ D+ I + ++ L NL+ L L + S
Sbjct 516 QELHLCHCPAKVEQTAFSFLRDHLRCLHVKFTDVAEIPAWVYL-LKNLRELYLIGNLNSE 574
Query 394 --RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
+ + E+ L H L IL++ N ++K+ S+ HL L + N+ + L
Sbjct 575 NNKMIGLESLRELRH--LKILHVKSN-LTKVPSNITDVAPHLTKLVIH-NDGTKLLVLNS 630
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
+ + N+ E+ L + ++ F+L +LQ L L+ ++ ++ S FQ L+ LT L
Sbjct 631 LKKMMNVAELELQNCELERIPHAIFSL-SNLQELDLKSNNIRTIEEIIS-FQHLKRLTCL 688
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLES 571
L +N I I + ++ LE L +N L L P+ L L L++
Sbjct 689 KLWHNKIVTIPPS-ITHVKNLESLYFSNNKLESL--------PVAVF-SLQKLRCLDVSY 738
Query 572 NGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
N IP+E+ L L+ + + N ++ LP +F + L++LNL +N ITS+ +KV
Sbjct 739 NNISMIPIEI-GLLQNLQHLHITGNKVDILPKQLFKC-IKLRTLNLGQNCITSLPEKV-- 794
Query 632 PAFRNLTELDMRFNPFD 648
LT+L+++ N FD
Sbjct 795 GQLSQLTQLELKGNCFD 811
Score = 41.6 bits (96), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 82/330 (25%), Positives = 151/330 (46%), Gaps = 42/330 (13%)
Query 33 EVADCSHLKLTQVPD-DLPTNITVL-NLTHNQLRRLPAA------NFTRYSQLTSLDVGF 84
++ D LKL +P+ +P I+ + NL L PA +F R L L V F
Sbjct 488 DLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLR-DHLRCLHVKF 546
Query 85 NTISKLEPEL-----CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
++++ + ++L ++ LN ++N++ L ++ +L LH+ SN + K+
Sbjct 547 TDVAEIPAWVYLLKNLRELYLIGNLNSENNKMIGL--ESLRELRHLKILHVKSN-LTKVP 603
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
+N +L L + ++G L + ++ N+ EL L N +++ + IF+ S+L
Sbjct 604 SNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELELQNCELERIPHA---IFSLSNL 660
Query 200 KKLELSSNQIKEFSPGC-FHAIGRLFGLFL---NNVQLGPSLTEKLCLELANTSIRNLSL 255
++L+L SN I+ F + RL L L V + PS+T LE +L
Sbjct 661 QELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE-------SLYF 713
Query 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFS 315
SN++L + F L LD+SYNN++++ + L L++ + N + +
Sbjct 714 SNNKLESLPVAVF---SLQKLRCLDVSYNNISMIPIE-IGLLQNLQHLHITGNKVD-ILP 768
Query 316 HSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L +R LNL ++ + SLP+
Sbjct 769 KQLFKCIKLRTLNLGQN------CITSLPE 792
>6m04_F F Volume-regulated anion channel subunit LRRC8D
Length=866
Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 86/317 (27%), Positives = 154/317 (49%), Gaps = 25/317 (8%)
Query 336 QSISLASLP-KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
Q + L P K++ +F +L+ L L+++ D+ I + ++ L NL+ L L + S
Sbjct 516 QELHLCHCPAKVEQTAFSFLRDHLRCLHVKFTDVAEIPAWVYL-LKNLRELYLIGNLNSE 574
Query 394 --RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
+ + E+ L H L IL++ N ++K+ S+ HL L + N+ + L
Sbjct 575 NNKMIGLESLRELRH--LKILHVKSN-LTKVPSNITDVAPHLTKLVIH-NDGTKLLVLNS 630
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
+ + N+ E+ L + ++ F+L +LQ L L+ ++ ++ S FQ L+ LT L
Sbjct 631 LKKMMNVAELELQNCELERIPHAIFSL-SNLQELDLKSNNIRTIEEIIS-FQHLKRLTCL 688
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLES 571
L +N I I + ++ LE L +N L L P+ L L L++
Sbjct 689 KLWHNKIVTIPPS-ITHVKNLESLYFSNNKLESL--------PVAVF-SLQKLRCLDVSY 738
Query 572 NGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
N IP+E+ L L+ + + N ++ LP +F + L++LNL +N ITS+ +KV
Sbjct 739 NNISMIPIEI-GLLQNLQHLHITGNKVDILPKQLFKC-IKLRTLNLGQNCITSLPEKV-- 794
Query 632 PAFRNLTELDMRFNPFD 648
LT+L+++ N FD
Sbjct 795 GQLSQLTQLELKGNCFD 811
Score = 41.6 bits (96), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 82/330 (25%), Positives = 151/330 (46%), Gaps = 42/330 (13%)
Query 33 EVADCSHLKLTQVPD-DLPTNITVL-NLTHNQLRRLPAA------NFTRYSQLTSLDVGF 84
++ D LKL +P+ +P I+ + NL L PA +F R L L V F
Sbjct 488 DLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLR-DHLRCLHVKF 546
Query 85 NTISKLEPEL-----CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
++++ + ++L ++ LN ++N++ L ++ +L LH+ SN + K+
Sbjct 547 TDVAEIPAWVYLLKNLRELYLIGNLNSENNKMIGL--ESLRELRHLKILHVKSN-LTKVP 603
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
+N +L L + ++G L + ++ N+ EL L N +++ + IF+ S+L
Sbjct 604 SNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELELQNCELERIPHA---IFSLSNL 660
Query 200 KKLELSSNQIKEFSPGC-FHAIGRLFGLFL---NNVQLGPSLTEKLCLELANTSIRNLSL 255
++L+L SN I+ F + RL L L V + PS+T LE +L
Sbjct 661 QELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE-------SLYF 713
Query 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFS 315
SN++L + F L LD+SYNN++++ + L L++ + N + +
Sbjct 714 SNNKLESLPVAVF---SLQKLRCLDVSYNNISMIPIE-IGLLQNLQHLHITGNKVD-ILP 768
Query 316 HSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L +R LNL ++ + SLP+
Sbjct 769 KQLFKCIKLRTLNLGQN------CITSLPE 792
>6m04_C C Volume-regulated anion channel subunit LRRC8D
Length=866
Score = 54.3 bits (129), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 86/317 (27%), Positives = 154/317 (49%), Gaps = 25/317 (8%)
Query 336 QSISLASLP-KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
Q + L P K++ +F +L+ L L+++ D+ I + ++ L NL+ L L + S
Sbjct 516 QELHLCHCPAKVEQTAFSFLRDHLRCLHVKFTDVAEIPAWVYL-LKNLRELYLIGNLNSE 574
Query 394 --RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
+ + E+ L H L IL++ N ++K+ S+ HL L + N+ + L
Sbjct 575 NNKMIGLESLRELRH--LKILHVKSN-LTKVPSNITDVAPHLTKLVIH-NDGTKLLVLNS 630
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
+ + N+ E+ L + ++ F+L +LQ L L+ ++ ++ S FQ L+ LT L
Sbjct 631 LKKMMNVAELELQNCELERIPHAIFSL-SNLQELDLKSNNIRTIEEIIS-FQHLKRLTCL 688
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLES 571
L +N I I + ++ LE L +N L L P+ L L L++
Sbjct 689 KLWHNKIVTIPPS-ITHVKNLESLYFSNNKLESL--------PVAVF-SLQKLRCLDVSY 738
Query 572 NGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFG 631
N IP+E+ L L+ + + N ++ LP +F + L++LNL +N ITS+ +KV
Sbjct 739 NNISMIPIEI-GLLQNLQHLHITGNKVDILPKQLFKC-IKLRTLNLGQNCITSLPEKV-- 794
Query 632 PAFRNLTELDMRFNPFD 648
LT+L+++ N FD
Sbjct 795 GQLSQLTQLELKGNCFD 811
Score = 41.6 bits (96), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 82/330 (25%), Positives = 151/330 (46%), Gaps = 42/330 (13%)
Query 33 EVADCSHLKLTQVPD-DLPTNITVL-NLTHNQLRRLPAA------NFTRYSQLTSLDVGF 84
++ D LKL +P+ +P I+ + NL L PA +F R L L V F
Sbjct 488 DLTDLDVLKLELIPEAKIPAKISQMTNLQELHLCHCPAKVEQTAFSFLR-DHLRCLHVKF 546
Query 85 NTISKLEPEL-----CQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
++++ + ++L ++ LN ++N++ L ++ +L LH+ SN + K+
Sbjct 547 TDVAEIPAWVYLLKNLRELYLIGNLNSENNKMIGL--ESLRELRHLKILHVKSN-LTKVP 603
Query 140 NNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSL 199
+N +L L + ++G L + ++ N+ EL L N +++ + IF+ S+L
Sbjct 604 SNITDVAPHLTKLVIHNDGTKLLVLNSLKKMMNVAELELQNCELERIPHA---IFSLSNL 660
Query 200 KKLELSSNQIKEFSPGC-FHAIGRLFGLFL---NNVQLGPSLTEKLCLELANTSIRNLSL 255
++L+L SN I+ F + RL L L V + PS+T LE +L
Sbjct 661 QELDLKSNNIRTIEEIISFQHLKRLTCLKLWHNKIVTIPPSITHVKNLE-------SLYF 713
Query 256 SNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFS 315
SN++L + F L LD+SYNN++++ + L L++ + N + +
Sbjct 714 SNNKLESLPVAVF---SLQKLRCLDVSYNNISMIPIE-IGLLQNLQHLHITGNKVD-ILP 768
Query 316 HSLHGLFNVRYLNLKRSFTKQSISLASLPK 345
L +R LNL ++ + SLP+
Sbjct 769 KQLFKCIKLRTLNLGQN------CITSLPE 792
>3twi_D D Variable lymphocyte receptor B
Length=179
Score = 51.2 bits (121), Expect = 6e-06, Method: Compositional matrix adjust.
Identities = 46/165 (28%), Positives = 75/165 (45%), Gaps = 10/165 (6%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S +C L VP +PT VL+L NQ+ +L F +QLT L++ N
Sbjct 15 SQCSCSGTTVNCQERSLASVPAGIPTTTQVLHLYINQITKLEPGVFDSLTQLTYLNLAVN 74
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN-------SIQKI 138
++ L + KL L L L N+L + F +LT ++L +N I +
Sbjct 75 QLTALPVGVFDKLTKLTHLALHINQLKSIPMGVFDNLKSLTHIYLFNNPWDCECSDILYL 134
Query 139 KNNPFVKQKNLITLDLSHNGLSSTKL-GTQVQLENLQELLLSNNK 182
KN ++ Q I L + G+ + K GT + + E S +K
Sbjct 135 KN--WIVQHASIVNPLGNGGVDNVKCSGTNTPVRAVTEASTSPSK 177
Score = 48.1 bits (113), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 43/167 (26%), Positives = 67/167 (40%), Gaps = 33/167 (20%)
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
++L L N + +L PG L+ L LNL N +PV VF L +L +
Sbjct 43 QVLHLYINQITKL----EPG----VFDSLTQLTYLNLAVNQLTALPVGVFDKLTKLTHLA 94
Query 593 LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCE 652
L +N L ++P VF+N ++LT + + NP+DC C
Sbjct 95 LHINQLKSIPMGVFDN-------------------------LKSLTHIYLFNNPWDCECS 129
Query 653 SIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSCKDS 699
I + NWI + + + L + + N PVR +S S
Sbjct 130 DILYLKNWIVQHASIVNPLGNGGVDNVKCSGTNTPVRAVTEASTSPS 176
>8f79_C C Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 836
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8f77_A A Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 836
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8f79_A A Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 836
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8f79_E E Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 836
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>5xwu_B B Leucine-rich repeat and fibronectin type III domain-containing
protein 1
Length=365
Score = 53.1 bits (126), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 54/190 (28%), Positives = 73/190 (38%), Gaps = 34/190 (18%)
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
+ E+ L+ N + R FA + SL L L R + V + F LR L L L +
Sbjct 34 RRVVELRLTDNFIAAVRRRDFANMTSLVHLTLSRNTIGQV--AAGAFADLRALRALHLDS 91
Query 516 NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
N +A + D L GL L L L +N I +ES FD
Sbjct 92 NRLAEVRGDQLRGLGNLRHLILGNN------------------------QIRKVESAAFD 127
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR 635
L ++ +DL NNL LP V+L +L L NLI + + F
Sbjct 128 AF-------LSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNLIDHIAEGTF-VQLH 179
Query 636 NLTELDMRFN 645
L LDM N
Sbjct 180 KLVRLDMTSN 189
Score = 52.8 bits (125), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 38/124 (31%), Positives = 67/124 (54%), Gaps = 6/124 (5%)
Query 104 LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTK 163
L L N ++ + + FA T+L L L N+I ++ F + L L L N L+ +
Sbjct 39 LRLTDNFIAAVRRRDFANMTSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVR 98
Query 164 LGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGR 222
G Q++ L NL+ L+L NN+I+ ++S D F S+++ L+LS N ++ + A+G+
Sbjct 99 -GDQLRGLGNLRHLILGNNQIRKVESAAFDAFL-STVEDLDLSYNNLEALP---WEAVGQ 153
Query 223 LFGL 226
+ L
Sbjct 154 MVNL 157
Score = 48.9 bits (115), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 72/142 (51%), Gaps = 1/142 (1%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T++ L L+ N + ++ A F L +L + N ++++ + + L L+ L L +N+
Sbjct 58 TSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGLGNLRHLILGNNQ 117
Query 111 LSQLSDKTF-AFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
+ ++ F AF + + +L L N+++ + + NL TL L HN + GT VQ
Sbjct 118 IRKVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNLIDHIAEGTFVQ 177
Query 170 LENLQELLLSNNKIQALKSEEL 191
L L L +++N++ L + L
Sbjct 178 LHKLVRLDMTSNRLHKLPPDGL 199
Score = 45.8 bits (107), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 40/155 (26%), Positives = 72/155 (46%), Gaps = 14/155 (9%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
T+L L LS N + V +FA L L L+ N + + L GL N+R+L L +
Sbjct 58 TSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGLGNLRHLILGNNQ 117
Query 334 TKQSISLASLPKIDDFSFQ-WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
+ K++ +F +L +E L++ N++ + ++NL L+L ++
Sbjct 118 IR---------KVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNL-- 166
Query 393 LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
+ + TFV L L L++T N++ K+ D
Sbjct 167 IDHIAEGTFVQLHK--LVRLDMTSNRLHKLPPDGL 199
Score = 41.2 bits (95), Expect = 0.038, Method: Compositional matrix adjust.
Identities = 48/187 (26%), Positives = 81/187 (43%), Gaps = 32/187 (17%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I ++ F + +L +L+LS + ++ + F L L L+L N++
Sbjct 39 LRLTDNFIAAVRRRDFANMTSLVHLTLSRN--TIGQVAAGAFADL--RALRALHLDSNRL 94
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN-IFEIYLSYNKYLQLTRNSFAL 478
+++ D LG+L L LG N+I R +E+ F+ +LS + L L+ N+
Sbjct 95 AEVRGDQLRGLGNLRHLILGNNQI---------RKVESAAFDAFLSTVEDLDLSYNNLEA 145
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P + NL L L +N I +I + L KL LD+
Sbjct 146 LPW------------------EAVGQMVNLNTLTLDHNLIDHIAEGTFVQLHKLVRLDMT 187
Query 539 HNNLARL 545
N L +L
Sbjct 188 SNRLHKL 194
>8f79_B B Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 836
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8f77_B B Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 836
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>6hlu_A A Rab family protein
Length=974
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 57/182 (31%), Positives = 91/182 (50%), Gaps = 16/182 (9%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
++T L+L+ NQ+ + A LT L + N IS + P + L L L L N++
Sbjct 202 SLTELSLSSNQITDI--APLASLKSLTELSLSSNQISDIAP--LESLKSLTELQLSRNQI 257
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
S ++ +LTEL L SN I I P K+L L LS N +S + L
Sbjct 258 SDIA--PLESLKSLTELQLSSNQITDIA--PLASLKSLTELQLSRNQISD--IAPLESLN 311
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
+L +L L+ N+I + + + +SL +LELSSNQI + +P ++ L L+L++
Sbjct 312 SLSKLWLNGNQITDIAP----LASLNSLTELELSSNQITDIAP--LASLKSLSTLWLSSN 365
Query 232 QL 233
Q+
Sbjct 366 QI 367
Score = 41.6 bits (96), Expect = 0.043, Method: Compositional matrix adjust.
Identities = 89/318 (28%), Positives = 138/318 (43%), Gaps = 47/318 (15%)
Query 345 KIDDFS-FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETFV 402
KI D + + LK L L + N I I L +L LSLS N+ + + L E+
Sbjct 146 KISDIAPLESLKSLTELQLSSNQITDIAP--LASLKSLTELSLSGNNISDIAPL--ESLK 201
Query 403 SLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY 462
SL L+L+ N+I+ I + L L L L N+I + + L
Sbjct 202 SLTE-----LSLSSNQITDIA--PLASLKSLTELSLSSNQISDIAPLESLKSLTE----- 249
Query 463 LSYNKYLQLTRNSFALVPSLQRLM-LRRVALK-NVDSSPSPFQPLRNLTILDLSNNNIAN 520
LQL+RN + + L+ L L + L N + +P L++LT L LS N I++
Sbjct 250 ------LQLSRNQISDIAPLESLKSLTELQLSSNQITDIAPLASLKSLTELQLSRNQISD 303
Query 521 INDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PV 579
I LE L N+L++LW + N I L L+ L L L SN +I P+
Sbjct 304 IAP--LESL----------NSLSKLWLNGNQITDIAPLASLNSLTELELSSNQITDIAPL 351
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTE 639
K L L + ++++ L + +++SL S N I+ + + +LT
Sbjct 352 ASLKSLSTLWLSSNQISDIAPLASLESLSELSLSS-----NQISDISPLA---SLNSLTG 403
Query 640 LDMRFNPFDCTCESIAWF 657
D+R NP E+I F
Sbjct 404 FDVRRNPIKRLPETITGF 421
>7p6k_C C Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6g9l_A A Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5y_E E Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p6k_F F Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5v_A A Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5w_E E Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6g9o_E E Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6g9l_E E Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p6k_E E Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5w_D D Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6g9l_D D Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p6k_D D Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p6k_B B Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p6k_A A Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p60_D D Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p60_C C Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p60_B B Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5y_D D Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5y_C C Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p60_A A Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5y_F F Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5y_B B Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5w_C C Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5w_B B Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6g9o_A A Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6g9l_F F Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5y_A A Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5v_C C Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5w_A A Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5v_E E Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6g9o_B B Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6g9o_C C Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6g9o_F F Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6g9o_D D Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6g9l_C C Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6g9l_B B Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p60_E E Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p60_F F Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5w_F F Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>5xwu_D D Leucine-rich repeat and fibronectin type III domain-containing
protein 1
Length=365
Score = 53.1 bits (126), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 54/190 (28%), Positives = 73/190 (38%), Gaps = 34/190 (18%)
Query 456 ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSN 515
+ E+ L+ N + R FA + SL L L R + V + F LR L L L +
Sbjct 34 RRVVELRLTDNFIAAVRRRDFANMTSLVHLTLSRNTIGQV--AAGAFADLRALRALHLDS 91
Query 516 NNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFD 575
N +A + D L GL L L L +N I +ES FD
Sbjct 92 NRLAEVRGDQLRGLGNLRHLILGNN------------------------QIRKVESAAFD 127
Query 576 EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFR 635
L ++ +DL NNL LP V+L +L L NLI + + F
Sbjct 128 AF-------LSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNLIDHIAEGTF-VQLH 179
Query 636 NLTELDMRFN 645
L LDM N
Sbjct 180 KLVRLDMTSN 189
Score = 52.4 bits (124), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 38/124 (31%), Positives = 67/124 (54%), Gaps = 6/124 (5%)
Query 104 LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTK 163
L L N ++ + + FA T+L L L N+I ++ F + L L L N L+ +
Sbjct 39 LRLTDNFIAAVRRRDFANMTSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVR 98
Query 164 LGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGR 222
G Q++ L NL+ L+L NN+I+ ++S D F S+++ L+LS N ++ + A+G+
Sbjct 99 -GDQLRGLGNLRHLILGNNQIRKVESAAFDAFL-STVEDLDLSYNNLEALP---WEAVGQ 153
Query 223 LFGL 226
+ L
Sbjct 154 MVNL 157
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 37/142 (26%), Positives = 72/142 (51%), Gaps = 1/142 (1%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T++ L L+ N + ++ A F L +L + N ++++ + + L L+ L L +N+
Sbjct 58 TSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGLGNLRHLILGNNQ 117
Query 111 LSQLSDKTF-AFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
+ ++ F AF + + +L L N+++ + + NL TL L HN + GT VQ
Sbjct 118 IRKVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNLIDHIAEGTFVQ 177
Query 170 LENLQELLLSNNKIQALKSEEL 191
L L L +++N++ L + L
Sbjct 178 LHKLVRLDMTSNRLHKLPPDGL 199
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 40/155 (26%), Positives = 72/155 (46%), Gaps = 14/155 (9%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSF 333
T+L L LS N + V +FA L L L+ N + + L GL N+R+L L +
Sbjct 58 TSLVHLTLSRNTIGQVAAGAFADLRALRALHLDSNRLAEVRGDQLRGLGNLRHLILGNNQ 117
Query 334 TKQSISLASLPKIDDFSFQ-WLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
+ K++ +F +L +E L++ N++ + ++NL L+L ++
Sbjct 118 IR---------KVESAAFDAFLSTVEDLDLSYNNLEALPWEAVGQMVNLNTLTLDHNL-- 166
Query 393 LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
+ + TFV L L L++T N++ K+ D
Sbjct 167 IDHIAEGTFVQLHK--LVRLDMTSNRLHKLPPDGL 199
Score = 41.2 bits (95), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 48/187 (26%), Positives = 81/187 (43%), Gaps = 32/187 (17%)
Query 360 LNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKI 419
L + DN I ++ F + +L +L+LS + ++ + F L L L+L N++
Sbjct 39 LRLTDNFIAAVRRRDFANMTSLVHLTLSRN--TIGQVAAGAFADL--RALRALHLDSNRL 94
Query 420 SKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLEN-IFEIYLSYNKYLQLTRNSFAL 478
+++ D LG+L L LG N+I R +E+ F+ +LS + L L+ N+
Sbjct 95 AEVRGDQLRGLGNLRHLILGNNQI---------RKVESAAFDAFLSTVEDLDLSYNNLEA 145
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+P + NL L L +N I +I + L KL LD+
Sbjct 146 LPW------------------EAVGQMVNLNTLTLDHNLIDHIAEGTFVQLHKLVRLDMT 187
Query 539 HNNLARL 545
N L +L
Sbjct 188 SNRLHKL 194
>8b42_D D Volume-regulated anion channel subunit LRRC8A
Length=817
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 592 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 650
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 651 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 707
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 708 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 745
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 586 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 642
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 643 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 692
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 693 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 751
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 752 -GELTNLTQIELRGNRLEC 769
>8b42_C C Volume-regulated anion channel subunit LRRC8A
Length=817
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 592 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 650
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 651 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 707
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 708 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 745
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 586 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 642
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 643 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 692
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 693 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 751
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 752 -GELTNLTQIELRGNRLEC 769
>8b41_C C Volume-regulated anion channel subunit LRRC8A
Length=817
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 592 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 650
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 651 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 707
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 708 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 745
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 586 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 642
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 643 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 692
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 693 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 751
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 752 -GELTNLTQIELRGNRLEC 769
>8b41_A A Volume-regulated anion channel subunit LRRC8A
Length=817
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 592 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 650
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 651 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 707
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 708 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 745
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 586 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 642
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 643 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 692
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 693 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 751
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 752 -GELTNLTQIELRGNRLEC 769
>8b42_A A Volume-regulated anion channel subunit LRRC8A
Length=817
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 592 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 650
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 651 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 707
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 708 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 745
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 586 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 642
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 643 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 692
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 693 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 751
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 752 -GELTNLTQIELRGNRLEC 769
>8ds3_C C Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 836
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8ds3_A A Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 836
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8ds3_E E Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 836
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8ds3_B B Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 836
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8dre_A A Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 53.9 bits (128), Expect = 7e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 836
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8b42_B B Volume-regulated anion channel subunit LRRC8A
Length=817
Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 592 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 650
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 651 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 707
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 708 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 745
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 586 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 642
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 643 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 692
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 693 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 751
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 752 -GELTNLTQIELRGNRLEC 769
>8dre_B B Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 53.9 bits (128), Expect = 8e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 836
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>7p5v_B B Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.5 bits (127), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5v_F F Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.5 bits (127), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7p5v_D D Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 53.5 bits (127), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 707 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>8b41_B B Volume-regulated anion channel subunit LRRC8A
Length=817
Score = 53.5 bits (127), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 592 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 650
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 651 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 707
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 708 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 745
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 586 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 642
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 643 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 692
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 693 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 751
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 752 -GELTNLTQIELRGNRLEC 769
>8b41_D D Volume-regulated anion channel subunit LRRC8A
Length=817
Score = 53.5 bits (127), Expect = 9e-06, Method: Compositional matrix adjust.
Identities = 52/161 (32%), Positives = 83/161 (52%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 592 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 650
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 651 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 707
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 708 LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQ 745
Score = 48.9 bits (115), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 586 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 642
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 643 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 692
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 693 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 751
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 752 -GELTNLTQIELRGNRLEC 769
>3twi_E E Variable lymphocyte receptor B
Length=179
Score = 50.4 bits (119), Expect = 1e-05, Method: Compositional matrix adjust.
Identities = 44/158 (28%), Positives = 72/158 (46%), Gaps = 10/158 (6%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S +C L VP +PT VL+L NQ+ +L F +QLT L++ N
Sbjct 15 SQCSCSGTTVNCQERSLASVPAGIPTTTQVLHLYINQITKLEPGVFDSLTQLTYLNLAVN 74
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN-------SIQKI 138
++ L + KL L L L N+L + F +LT ++L +N I +
Sbjct 75 QLTALPVGVFDKLTKLTHLALHINQLKSIPMGVFDNLKSLTHIYLFNNPWDCECSDILYL 134
Query 139 KNNPFVKQKNLITLDLSHNGLSSTKL-GTQVQLENLQE 175
KN ++ Q I L + G+ + K GT + + E
Sbjct 135 KN--WIVQHASIVNPLGNGGVDNVKCSGTNTPVRAVTE 170
Score = 48.1 bits (113), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 43/167 (26%), Positives = 67/167 (40%), Gaps = 33/167 (20%)
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
++L L N + +L PG L+ L LNL N +PV VF L +L +
Sbjct 43 QVLHLYINQITKL----EPG----VFDSLTQLTYLNLAVNQLTALPVGVFDKLTKLTHLA 94
Query 593 LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCE 652
L +N L ++P VF+N ++LT + + NP+DC C
Sbjct 95 LHINQLKSIPMGVFDN-------------------------LKSLTHIYLFNNPWDCECS 129
Query 653 SIAWFVNWINETHTNIPELSSHYLCNTPPHYHGFPVRLFDTSSCKDS 699
I + NWI + + + L + + N PVR +S S
Sbjct 130 DILYLKNWIVQHASIVNPLGNGGVDNVKCSGTNTPVRAVTEASTSPS 176
>7d2t_C C Ras suppressor protein 1
Length=282
Score = 51.2 bits (121), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 59/193 (31%), Positives = 91/193 (47%), Gaps = 20/193 (10%)
Query 18 GMLCASSTTKCTVSHEVADCSHLKLTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYS 75
G+ S T+ +SH KLT VP ++ N+ VLN +NQ+ LP +
Sbjct 40 GLFTLSHITQLVLSHN-------KLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQ 91
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS-DKTFAFCTNLTELHLMSNS 134
+L L++G N ++ L P LP L+VL+L +N LS+ S F + T L L+L N
Sbjct 92 KLKHLNLGMNRLNTL-PRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDND 150
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSS--TKLGTQVQLENLQELLLSNNKIQALKSE--E 190
+ + + K L L L N L S ++G +L L+EL + N++ L E
Sbjct 151 FEILPPD-IGKLTKLQILSLRDNDLISLPKEIG---ELTQLKELHIQGNRLTVLPPELGN 206
Query 191 LDIFANSSLKKLE 203
LD+ + K E
Sbjct 207 LDLTGQKQVFKAE 219
Score = 33.9 bits (76), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 42/159 (26%), Positives = 70/159 (44%), Gaps = 38/159 (24%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+ SLQ+L + + +++ P F L L +LDL+ NN++
Sbjct 87 ISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLS------------------- 127
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+++ PG Y L+ L L L N F+ +P ++ K L +L+I+ L N+L
Sbjct 128 --------ENSLPGNFFY----LTTLRALYLSDNDFEILPPDIGK-LTKLQILSLRDNDL 174
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNL 637
+LP + LK L++Q N +T V P NL
Sbjct 175 ISLPKEI-GELTQLKELHIQGNRLT-----VLPPELGNL 207
>7d2u_A A Ras suppressor protein 1
Length=282
Score = 51.2 bits (121), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 59/193 (31%), Positives = 91/193 (47%), Gaps = 20/193 (10%)
Query 18 GMLCASSTTKCTVSHEVADCSHLKLTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYS 75
G+ S T+ +SH KLT VP ++ N+ VLN +NQ+ LP +
Sbjct 40 GLFTLSHITQLVLSHN-------KLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQ 91
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS-DKTFAFCTNLTELHLMSNS 134
+L L++G N ++ L P LP L+VL+L +N LS+ S F + T L L+L N
Sbjct 92 KLKHLNLGMNRLNTL-PRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDND 150
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSS--TKLGTQVQLENLQELLLSNNKIQALKSE--E 190
+ + + K L L L N L S ++G +L L+EL + N++ L E
Sbjct 151 FEILPPD-IGKLTKLQILSLRDNDLISLPKEIG---ELTQLKELHIQGNRLTVLPPELGN 206
Query 191 LDIFANSSLKKLE 203
LD+ + K E
Sbjct 207 LDLTGQKQVFKAE 219
Score = 33.9 bits (76), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 42/159 (26%), Positives = 70/159 (44%), Gaps = 38/159 (24%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+ SLQ+L + + +++ P F L L +LDL+ NN++
Sbjct 87 ISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLS------------------- 127
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+++ PG Y L+ L L L N F+ +P ++ K L +L+I+ L N+L
Sbjct 128 --------ENSLPGNFFY----LTTLRALYLSDNDFEILPPDIGK-LTKLQILSLRDNDL 174
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNL 637
+LP + LK L++Q N +T V P NL
Sbjct 175 ISLPKEI-GELTQLKELHIQGNRLT-----VLPPELGNL 207
>7d2t_A A Ras suppressor protein 1
Length=282
Score = 51.2 bits (121), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 59/193 (31%), Positives = 91/193 (47%), Gaps = 20/193 (10%)
Query 18 GMLCASSTTKCTVSHEVADCSHLKLTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYS 75
G+ S T+ +SH KLT VP ++ N+ VLN +NQ+ LP +
Sbjct 40 GLFTLSHITQLVLSHN-------KLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQ 91
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS-DKTFAFCTNLTELHLMSNS 134
+L L++G N ++ L P LP L+VL+L +N LS+ S F + T L L+L N
Sbjct 92 KLKHLNLGMNRLNTL-PRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDND 150
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSS--TKLGTQVQLENLQELLLSNNKIQALKSE--E 190
+ + + K L L L N L S ++G +L L+EL + N++ L E
Sbjct 151 FEILPPD-IGKLTKLQILSLRDNDLISLPKEIG---ELTQLKELHIQGNRLTVLPPELGN 206
Query 191 LDIFANSSLKKLE 203
LD+ + K E
Sbjct 207 LDLTGQKQVFKAE 219
Score = 33.9 bits (76), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 42/159 (26%), Positives = 70/159 (44%), Gaps = 38/159 (24%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+ SLQ+L + + +++ P F L L +LDL+ NN++
Sbjct 87 ISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLS------------------- 127
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+++ PG Y L+ L L L N F+ +P ++ K L +L+I+ L N+L
Sbjct 128 --------ENSLPGNFFY----LTTLRALYLSDNDFEILPPDIGK-LTKLQILSLRDNDL 174
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNL 637
+LP + LK L++Q N +T V P NL
Sbjct 175 ISLPKEI-GELTQLKELHIQGNRLT-----VLPPELGNL 207
>4q3i_B B OsSERK2 D128N
Length=244
Score = 50.8 bits (120), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 43/160 (27%), Positives = 74/160 (46%), Gaps = 9/160 (6%)
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
P ++ +DL N ++ L L+ L+ L+L NN++ G L L++
Sbjct 44 PDNSVIRVDLGNAQLSGALVPQLGQLKNLQYLELYSNNIS--------GTIPNELGNLTN 95
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L LNL N F E L++L+ + L N+L+ N +L+ L L N +
Sbjct 96 LVSLNLYLNNFTGFIPETLGQLYKLRFLRLNNNSLSGSIPKSLTNITTLQELALDTNQLK 155
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 156 SVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 194
Score = 34.3 bits (77), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 32/105 (30%), Positives = 50/105 (48%), Gaps = 2/105 (2%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
NL L L SN+I N NL++L+L N + T QL L+ L L+NN +
Sbjct 71 NLQYLELYSNNISGTIPNELGNLTNLVSLNLYLNNFTGFIPETLGQLYKLRFLRLNNNSL 130
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+ L ++L++L L +NQ+K G F + L ++L
Sbjct 131 SGSIPKSLTNI--TTLQELALDTNQLKSVPDGIFDRLTSLQKIWL 173
>7lt9_A A Ras suppressor protein 1
Length=280
Score = 51.2 bits (121), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 59/193 (31%), Positives = 91/193 (47%), Gaps = 20/193 (10%)
Query 18 GMLCASSTTKCTVSHEVADCSHLKLTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYS 75
G+ S T+ +SH KLT VP ++ N+ VLN +NQ+ LP +
Sbjct 38 GLFTLSHITQLVLSHN-------KLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQ 89
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS-DKTFAFCTNLTELHLMSNS 134
+L L++G N ++ L P LP L+VL+L +N LS+ S F + T L L+L N
Sbjct 90 KLKHLNLGMNRLNTL-PRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDND 148
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSS--TKLGTQVQLENLQELLLSNNKIQALKSE--E 190
+ + + K L L L N L S ++G +L L+EL + N++ L E
Sbjct 149 FEILPPD-IGKLTKLQILSLRDNDLISLPKEIG---ELTQLKELHIQGNRLTVLPPELGN 204
Query 191 LDIFANSSLKKLE 203
LD+ + K E
Sbjct 205 LDLTGQKQVFKAE 217
Score = 34.3 bits (77), Expect = 5.8, Method: Compositional matrix adjust.
Identities = 42/159 (26%), Positives = 70/159 (44%), Gaps = 38/159 (24%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+ SLQ+L + + +++ P F L L +LDL+ NN++
Sbjct 85 ISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLS------------------- 125
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+++ PG Y L+ L L L N F+ +P ++ K L +L+I+ L N+L
Sbjct 126 --------ENSLPGNFFY----LTTLRALYLSDNDFEILPPDIGK-LTKLQILSLRDNDL 172
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNL 637
+LP + LK L++Q N +T V P NL
Sbjct 173 ISLPKEI-GELTQLKELHIQGNRLT-----VLPPELGNL 205
>7xzh_A A Volume-regulated anion channel subunit LRRC8A
Length=808
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>2xot_A A Amphoterin-induced protein 1
Length=361
Score = 51.6 bits (122), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 53/207 (26%), Positives = 90/207 (43%), Gaps = 35/207 (17%)
Query 498 SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF 557
S F P+ NL LDLS+N++ +++ + L+ LE+L L +N++ + ++A
Sbjct 80 SSEAFVPVPNLRYLDLSSNHLHTLDEFLFSDLQALEVLLLYNNHIVVVDRNA-------- 131
Query 558 LKGLSHLHILNLESNGFDEIPVEVFK---DLFELKIIDLGLNNLNTLPASVFNNQVSLKS 614
+ ++ L L L N PVE+ K L +L ++DL N L LP +
Sbjct 132 FEDMAQLQKLYLSQNQISRFPVELIKXXXXLPKLMLLDLSSNKLKKLPLT---------- 181
Query 615 LNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSH 674
+LQK PA+ L + NP +C C+ F +W +++ +
Sbjct 182 -DLQK-----------LPAWVK-NGLYLHNNPLECDCKLYQLFSHWQYRQLSSVMDFQED 228
Query 675 YLCNTPPHYHG-FPVRLFDTSSCKDSA 700
C H F + F+ S K+SA
Sbjct 229 LYCMHSKKLHNIFSLDFFNCSEYKESA 255
Score = 48.5 bits (114), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 47/123 (38%), Positives = 61/123 (50%), Gaps = 4/123 (3%)
Query 92 PELCQKLP-MLKVLNLQHNELSQL-SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
P + Q LP +L+L HN LS+L ++ T TNL L L N + I + FV NL
Sbjct 31 PNVPQSLPSYTALLDLSHNNLSRLRAEWTPTRLTNLHSLLLSHNHLNFISSEAFVPVPNL 90
Query 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
LDLS N L + L+ L+ LLL NN I + + A L+KL LS NQI
Sbjct 91 RYLDLSSNHLHTLDEFLFSDLQALEVLLLYNNHIVVVDRNAFEDMAQ--LQKLYLSQNQI 148
Query 210 KEF 212
F
Sbjct 149 SRF 151
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 34/97 (35%), Positives = 51/97 (53%), Gaps = 7/97 (7%)
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDL 593
+LDL HNNL+RL P L++LH L L N + I E F + L+ +DL
Sbjct 43 LLDLSHNNLSRLRAEWTP-------TRLTNLHSLLLSHNHLNFISSEAFVPVPNLRYLDL 95
Query 594 GLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVF 630
N+L+TL +F++ +L+ L L N I V++ F
Sbjct 96 SSNHLHTLDEFLFSDLQALEVLLLYNNHIVVVDRNAF 132
Score = 38.1 bits (87), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 42/151 (28%), Positives = 71/151 (47%), Gaps = 19/151 (13%)
Query 277 TMLDLSYNNLNVVGNDSFAWLP----QLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRS 332
+LDLS+NNL+ + + W P L L +N++ + S + + N+RYL+L +
Sbjct 42 ALLDLSHNNLSRLRAE---WTPTRLTNLHSLLLSHNHLNFISSEAFVPVPNLRYLDLSSN 98
Query 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
L +D+F F L+ LE L + +N I + N F + L+ L LS +
Sbjct 99 H---------LHTLDEFLFSDLQALEVLLLYNNHIVVVDRNAFEDMAQLQKLYLSQN--Q 147
Query 393 LRTLTNETFVSLAHSP-LHILNLTKNKISKI 422
+ E P L +L+L+ NK+ K+
Sbjct 148 ISRFPVELIKXXXXLPKLMLLDLSSNKLKKL 178
Score = 37.7 bits (86), Expect = 0.50, Method: Compositional matrix adjust.
Identities = 45/173 (26%), Positives = 65/173 (38%), Gaps = 32/173 (18%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLP-------------------------TNITVL 56
S C + + CS +L VP LP TN+ L
Sbjct 10 VSCPANCLCASNILSCSKQQLPNVPQSLPSYTALLDLSHNNLSRLRAEWTPTRLTNLHSL 69
Query 57 NLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSD 116
L+HN L + + F L LD+ N + L+ L L L+VL L +N + +
Sbjct 70 LLSHNHLNFISSEAFVPVPNLRYLDLSSNHLHTLDEFLFSDLQALEVLLLYNNHIVVVDR 129
Query 117 KTFAFCTNLTELHLMSNSIQK-----IKNNPFVKQKNLITLDLSHNGLSSTKL 164
F L +L+L N I + IK + + L+ LDLS N L L
Sbjct 130 NAFEDMAQLQKLYLSQNQISRFPVELIKXXXXLPK--LMLLDLSSNKLKKLPL 180
>5zsu_F F Volume-regulated anion channel subunit LRRC8A
Length=818
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>5zsu_D D Volume-regulated anion channel subunit LRRC8A
Length=818
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>5zsu_B B Volume-regulated anion channel subunit LRRC8A
Length=818
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7lt8_A A Ras suppressor protein 1
Length=280
Score = 51.2 bits (121), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 59/193 (31%), Positives = 91/193 (47%), Gaps = 20/193 (10%)
Query 18 GMLCASSTTKCTVSHEVADCSHLKLTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYS 75
G+ S T+ +SH KLT VP ++ N+ VLN +NQ+ LP +
Sbjct 38 GLFTLSHITQLVLSHN-------KLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQ 89
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS-DKTFAFCTNLTELHLMSNS 134
+L L++G N ++ L P LP L+VL+L +N LS+ S F + T L L+L N
Sbjct 90 KLKHLNLGMNRLNTL-PRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDND 148
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSS--TKLGTQVQLENLQELLLSNNKIQALKSE--E 190
+ + + K L L L N L S ++G +L L+EL + N++ L E
Sbjct 149 FEILPPD-IGKLTKLQILSLRDNDLISLPKEIG---ELTQLKELHIQGNRLTVLPPELGN 204
Query 191 LDIFANSSLKKLE 203
LD+ + K E
Sbjct 205 LDLTGQKQVFKAE 217
Score = 34.3 bits (77), Expect = 5.6, Method: Compositional matrix adjust.
Identities = 42/159 (26%), Positives = 70/159 (44%), Gaps = 38/159 (24%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQ 538
+ SLQ+L + + +++ P F L L +LDL+ NN++
Sbjct 85 ISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLS------------------- 125
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+++ PG Y L+ L L L N F+ +P ++ K L +L+I+ L N+L
Sbjct 126 --------ENSLPGNFFY----LTTLRALYLSDNDFEILPPDIGK-LTKLQILSLRDNDL 172
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNL 637
+LP + LK L++Q N +T V P NL
Sbjct 173 ISLPKEI-GELTQLKELHIQGNRLT-----VLPPELGNL 205
>5zsu_C C Volume-regulated anion channel subunit LRRC8A
Length=818
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>5zsu_A A Volume-regulated anion channel subunit LRRC8A
Length=818
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>5zsu_E E Volume-regulated anion channel subunit LRRC8A
Length=818
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7xzh_C C Volume-regulated anion channel subunit LRRC8A
Length=808
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7xzh_F F Volume-regulated anion channel subunit LRRC8A
Length=808
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7xzh_E E Volume-regulated anion channel subunit LRRC8A
Length=808
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7xzh_D D Volume-regulated anion channel subunit LRRC8A
Length=808
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>7xzh_B B Volume-regulated anion channel subunit LRRC8A
Length=808
Score = 52.4 bits (124), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>4q3i_A A OsSERK2 D128N
Length=244
Score = 50.4 bits (119), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 43/160 (27%), Positives = 74/160 (46%), Gaps = 9/160 (6%)
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
P ++ +DL N ++ L L+ L+ L+L NN++ G L L++
Sbjct 44 PDNSVIRVDLGNAQLSGALVPQLGQLKNLQYLELYSNNIS--------GTIPNELGNLTN 95
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L LNL N F E L++L+ + L N+L+ N +L+ L L N +
Sbjct 96 LVSLNLYLNNFTGFIPETLGQLYKLRFLRLNNNSLSGSIPKSLTNITTLQELALDTNQLK 155
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 156 SVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 194
Score = 34.3 bits (77), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 32/105 (30%), Positives = 50/105 (48%), Gaps = 2/105 (2%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
NL L L SN+I N NL++L+L N + T QL L+ L L+NN +
Sbjct 71 NLQYLELYSNNISGTIPNELGNLTNLVSLNLYLNNFTGFIPETLGQLYKLRFLRLNNNSL 130
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+ L ++L++L L +NQ+K G F + L ++L
Sbjct 131 SGSIPKSLTNI--TTLQELALDTNQLKSVPDGIFDRLTSLQKIWL 173
>6djb_A A Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6djb_E C Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6djb_C E Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 52.0 bits (123), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6djb_F D Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6djb_D F Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>6djb_B B Volume-regulated anion channel subunit LRRC8A
Length=810
Score = 52.0 bits (123), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 51/161 (32%), Positives = 82/161 (51%), Gaps = 8/161 (5%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 591 ANLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +
Sbjct 650 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 706
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIK 210
L+NLQ L ++ N+I+ L E +F L+ L L +N ++
Sbjct 707 LQNLQNLAITANRIETLPPE---LFQCRKLRALHLGNNVLQ 744
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 54/199 (27%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 585 NSLKKMANLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 641
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 642 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 691
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA ++ N++ L++L+L N++ S+ +V
Sbjct 692 LSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRV- 750
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 751 -GELTNLTQIELRGNRLEC 768
>4mn8_A A LRR receptor-like serine/threonine-protein kinase FLS2
Length=782
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 152/600 (25%), Positives = 244/600 (41%), Gaps = 106/600 (18%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
+ E+ +CS L L L NQL A QL +L + N ++
Sbjct 232 IPAEIGNCSSL-------------VQLELYDNQLTGKIPAELGNLVQLQALRIYKNKLTS 278
Query 90 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
P +L L L L N L + F +L L L SN+ +NL
Sbjct 279 SIPSSLFRLTQLTHLGLSENHLVGPISEEIGFLESLEVLTLHSNNFTGEFPQSITNLRNL 338
Query 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
L + N +S L NL+ L +N + I + LK L+LS NQ+
Sbjct 339 TVLTVGFNNISGELPADLGLLTNLRNLSAHDNLLTGPIPSS--ISNCTGLKLLDLSHNQM 396
Query 210 KEFSPGCFHAIGRLFGLFLNNVQLGPS-LTEKLCLELANTS-IRNLSLSNSQLSTTSNTT 267
P F + F + +G + T ++ ++ N S + LS++++ L+ T
Sbjct 397 TGEIPRGFGRMNLTF------ISIGRNHFTGEIPDDIFNCSNLETLSVADNNLTGTLK-P 449
Query 268 FLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
+G K L +L +SYN+L +P+ E N++ L N+ YL
Sbjct 450 LIG-KLQKLRILQVSYNSLT-------GPIPR------EIGNLKDL---------NILYL 486
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG-IKSNMFTGLINLKYLSL 386
+ FT + +P+ L L+ L M ND+ G I MF + L L L
Sbjct 487 H-SNGFTGR------IPR----EMSNLTLLQGLRMYSNDLEGPIPEEMFDMKL-LSVLDL 534
Query 387 SNS---------FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
SN+ F+ L +LT L+L NK + + L L D
Sbjct 535 SNNKFSGQIPALFSKLESLT-------------YLSLQGNKFNGSIPASLKSLSLLNTFD 581
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP-SLQRL-MLRRVALKN- 494
+ N + + G+ L+N+ ++YL+++ L LT +P L +L M++ + L N
Sbjct 582 ISDNLLTGTIPGELLASLKNM-QLYLNFSNNL-LT----GTIPKELGKLEMVQEIDLSNN 635
Query 495 --VDSSPSPFQPLRNLTILDLSNNNIAN-INDDMLEGLEKLEILDLQHNNLARLWKHANP 551
S P Q +N+ LD S NN++ I D++ +G++ + L+L N+ + +
Sbjct 636 LFSGSIPRSLQACKNVFTLDFSQNNLSGHIPDEVFQGMDMIISLNLSRNSFSGEIPQS-- 693
Query 552 GGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLNNLNT-LPAS-VFNN 608
++HL L+L SN EIP E +L LK + L NNL +P S VF N
Sbjct 694 ------FGNMTHLVSLDLSSNNLTGEIP-ESLANLSTLKHLKLASNNLKGHVPESGVFKN 746
Score = 43.5 bits (101), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 122/509 (24%), Positives = 190/509 (37%), Gaps = 88/509 (17%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
NI L+L +N L + S L + +N ++ PE L L++ N L
Sbjct 121 NIFYLDLRNNLLSGDVPEEICKTSSLVLIGFDYNNLTGKIPECLGDLVHLQMFVAAGNHL 180
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ + NLT+L DLS N L+ L
Sbjct 181 TGSIPVSIGTLANLTDL------------------------DLSGNQLTGKIPRDFGNLL 216
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNV 231
NLQ L+L+ N ++ E I SSL +LEL NQ
Sbjct 217 NLQSLVLTENLLEGDIPAE--IGNCSSLVQLELYDNQ----------------------- 251
Query 232 QLGPSLTEKLCLELAN-TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
LT K+ EL N ++ L + ++L+++ ++ + T LT L LS N+L
Sbjct 252 -----LTGKIPAELGNLVQLQALRIYKNKLTSSIPSSL--FRLTQLTHLGLSENHLVGPI 304
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
++ +L LE L NN F S+ L N+ L + F S LP
Sbjct 305 SEEIGFLESLEVLTLHSNNFTGEFPQSITNLRNLTVLTV--GFNNIS---GELPA----D 355
Query 351 FQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTS--LRTLT--NETFVSLA 405
L L +L+ DN + G + + LK L LS N T R N TF+S+
Sbjct 356 LGLLTNLRNLSAHDNLLTGPIPSSISNCTGLKLLDLSHNQMTGEIPRGFGRMNLTFISIG 415
Query 406 H--------------SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
S L L++ N ++ L L +L + N + + +E
Sbjct 416 RNHFTGEIPDDIFNCSNLETLSVADNNLTGTLKPLIGKLQKLRILQVSYNSLTGPIP-RE 474
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
L+++ +YL N + + + LQ L + L+ P ++ L++L
Sbjct 475 IGNLKDLNILYLHSNGFTGRIPREMSNLTLLQGLRMYSNDLEG--PIPEEMFDMKLLSVL 532
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHN 540
DLSNN + + LE L L LQ N
Sbjct 533 DLSNNKFSGQIPALFSKLESLTYLSLQGN 561
>8b40_E E Volume-regulated anion channel subunit LRRC8C
Length=811
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 81/294 (28%), Positives = 142/294 (48%), Gaps = 23/294 (8%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT--SLRTLTNETFVSLAHSPLHILNL 414
L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+ L L IL++
Sbjct 494 LKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHXXXKNVTLESLRDL--KSLKILSI 550
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
N +SKI HL+ + + N+ + + + + N+ E+ L + ++
Sbjct 551 KSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELELVHCDLERIPHA 608
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I + ++ L LE
Sbjct 609 VFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIPEH-IKKLTSLER 665
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L HN + L H I + L+L N IP E+ L L+ +
Sbjct 666 LFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI-GVLQSLQYFSIT 715
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
N + +LP ++ + LK+L + KN ++ + K+ F L+ LD++ N F+
Sbjct 716 CNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDIKGNHFE 766
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 590 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 648
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + T+L L N ++ + ++ F+ K + LDLS+N + V
Sbjct 649 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 705
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LFL+
Sbjct 706 LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LFLS 756
Query 230 NVQLGPSLTEKLCLELAN 247
+ + + E L EL +
Sbjct 757 YLDIKGNHFEVLPPELGD 774
>8b40_A A Volume-regulated anion channel subunit LRRC8C
Length=811
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 81/294 (28%), Positives = 142/294 (48%), Gaps = 23/294 (8%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT--SLRTLTNETFVSLAHSPLHILNL 414
L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+ L L IL++
Sbjct 494 LKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHXXXKNVTLESLRDL--KSLKILSI 550
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
N +SKI HL+ + + N+ + + + + N+ E+ L + ++
Sbjct 551 KSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELELVHCDLERIPHA 608
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I + ++ L LE
Sbjct 609 VFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIPEH-IKKLTSLER 665
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L HN + L H I + L+L N IP E+ L L+ +
Sbjct 666 LFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI-GVLQSLQYFSIT 715
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
N + +LP ++ + LK+L + KN ++ + K+ F L+ LD++ N F+
Sbjct 716 CNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDIKGNHFE 766
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 590 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 648
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + T+L L N ++ + ++ F+ K + LDLS+N + V
Sbjct 649 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 705
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LFL+
Sbjct 706 LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LFLS 756
Query 230 NVQLGPSLTEKLCLELAN 247
+ + + E L EL +
Sbjct 757 YLDIKGNHFEVLPPELGD 774
>8b40_G G Volume-regulated anion channel subunit LRRC8C
Length=811
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 81/294 (28%), Positives = 142/294 (48%), Gaps = 23/294 (8%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT--SLRTLTNETFVSLAHSPLHILNL 414
L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+ L L IL++
Sbjct 494 LKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHXXXKNVTLESLRDL--KSLKILSI 550
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
N +SKI HL+ + + N+ + + + + N+ E+ L + ++
Sbjct 551 KSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELELVHCDLERIPHA 608
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I + ++ L LE
Sbjct 609 VFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIPEH-IKKLTSLER 665
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L HN + L H I + L+L N IP E+ L L+ +
Sbjct 666 LFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI-GVLQSLQYFSIT 715
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
N + +LP ++ + LK+L + KN ++ + K+ F L+ LD++ N F+
Sbjct 716 CNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDIKGNHFE 766
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 590 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 648
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + T+L L N ++ + ++ F+ K + LDLS+N + V
Sbjct 649 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 705
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LFL+
Sbjct 706 LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LFLS 756
Query 230 NVQLGPSLTEKLCLELAN 247
+ + + E L EL +
Sbjct 757 YLDIKGNHFEVLPPELGD 774
>8b40_D D Volume-regulated anion channel subunit LRRC8C
Length=811
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 81/294 (28%), Positives = 142/294 (48%), Gaps = 23/294 (8%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT--SLRTLTNETFVSLAHSPLHILNL 414
L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+ L L IL++
Sbjct 494 LKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHXXXKNVTLESLRDL--KSLKILSI 550
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
N +SKI HL+ + + N+ + + + + N+ E+ L + ++
Sbjct 551 KSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELELVHCDLERIPHA 608
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I + ++ L LE
Sbjct 609 VFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIPEH-IKKLTSLER 665
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L HN + L H I + L+L N IP E+ L L+ +
Sbjct 666 LFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI-GVLQSLQYFSIT 715
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
N + +LP ++ + LK+L + KN ++ + K+ F L+ LD++ N F+
Sbjct 716 CNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDIKGNHFE 766
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 590 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 648
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + T+L L N ++ + ++ F+ K + LDLS+N + V
Sbjct 649 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 705
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LFL+
Sbjct 706 LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LFLS 756
Query 230 NVQLGPSLTEKLCLELAN 247
+ + + E L EL +
Sbjct 757 YLDIKGNHFEVLPPELGD 774
>8b40_B B Volume-regulated anion channel subunit LRRC8C
Length=811
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 81/294 (28%), Positives = 142/294 (48%), Gaps = 23/294 (8%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT--SLRTLTNETFVSLAHSPLHILNL 414
L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+ L L IL++
Sbjct 494 LKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHXXXKNVTLESLRDL--KSLKILSI 550
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
N +SKI HL+ + + N+ + + + + N+ E+ L + ++
Sbjct 551 KSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELELVHCDLERIPHA 608
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I + ++ L LE
Sbjct 609 VFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIPEH-IKKLTSLER 665
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L HN + L H I + L+L N IP E+ L L+ +
Sbjct 666 LFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI-GVLQSLQYFSIT 715
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
N + +LP ++ + LK+L + KN ++ + K+ F L+ LD++ N F+
Sbjct 716 CNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDIKGNHFE 766
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 590 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 648
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + T+L L N ++ + ++ F+ K + LDLS+N + V
Sbjct 649 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 705
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LFL+
Sbjct 706 LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LFLS 756
Query 230 NVQLGPSLTEKLCLELAN 247
+ + + E L EL +
Sbjct 757 YLDIKGNHFEVLPPELGD 774
>8b40_F F Volume-regulated anion channel subunit LRRC8C
Length=811
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 81/294 (28%), Positives = 142/294 (48%), Gaps = 23/294 (8%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT--SLRTLTNETFVSLAHSPLHILNL 414
L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+ L L IL++
Sbjct 494 LKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHXXXKNVTLESLRDL--KSLKILSI 550
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
N +SKI HL+ + + N+ + + + + N+ E+ L + ++
Sbjct 551 KSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELELVHCDLERIPHA 608
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I + ++ L LE
Sbjct 609 VFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIPEH-IKKLTSLER 665
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L HN + L H I + L+L N IP E+ L L+ +
Sbjct 666 LFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI-GVLQSLQYFSIT 715
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
N + +LP ++ + LK+L + KN ++ + K+ F L+ LD++ N F+
Sbjct 716 CNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDIKGNHFE 766
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 590 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 648
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + T+L L N ++ + ++ F+ K + LDLS+N + V
Sbjct 649 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 705
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LFL+
Sbjct 706 LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LFLS 756
Query 230 NVQLGPSLTEKLCLELAN 247
+ + + E L EL +
Sbjct 757 YLDIKGNHFEVLPPELGD 774
>8b40_C C Volume-regulated anion channel subunit LRRC8C
Length=811
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 81/294 (28%), Positives = 142/294 (48%), Gaps = 23/294 (8%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT--SLRTLTNETFVSLAHSPLHILNL 414
L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+ L L IL++
Sbjct 494 LKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHXXXKNVTLESLRDL--KSLKILSI 550
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
N +SKI HL+ + + N+ + + + + N+ E+ L + ++
Sbjct 551 KSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELELVHCDLERIPHA 608
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I + ++ L LE
Sbjct 609 VFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIPEH-IKKLTSLER 665
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L HN + L H I + L+L N IP E+ L L+ +
Sbjct 666 LFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI-GVLQSLQYFSIT 715
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
N + +LP ++ + LK+L + KN ++ + K+ F L+ LD++ N F+
Sbjct 716 CNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDIKGNHFE 766
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 590 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 648
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + T+L L N ++ + ++ F+ K + LDLS+N + V
Sbjct 649 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 705
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LFL+
Sbjct 706 LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LFLS 756
Query 230 NVQLGPSLTEKLCLELAN 247
+ + + E L EL +
Sbjct 757 YLDIKGNHFEVLPPELGD 774
>8b42_E E Volume-regulated anion channel subunit LRRC8C
Length=811
Score = 51.6 bits (122), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 81/294 (28%), Positives = 142/294 (48%), Gaps = 23/294 (8%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT--SLRTLTNETFVSLAHSPLHILNL 414
L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+ L L IL++
Sbjct 494 LKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHXXXKNVTLESLRDL--KSLKILSI 550
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
N +SKI HL+ + + N+ + + + + N+ E+ L + ++
Sbjct 551 KSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELELVHCDLERIPHA 608
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I + ++ L LE
Sbjct 609 VFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIPEH-IKKLTSLER 665
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L HN + L H I + L+L N IP E+ L L+ +
Sbjct 666 LFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI-GVLQSLQYFSIT 715
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
N + +LP ++ + LK+L + KN ++ + K+ F L+ LD++ N F+
Sbjct 716 CNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDIKGNHFE 766
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 590 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 648
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + T+L L N ++ + ++ F+ K + LDLS+N + V
Sbjct 649 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 705
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LFL+
Sbjct 706 LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LFLS 756
Query 230 NVQLGPSLTEKLCLELAN 247
+ + + E L EL +
Sbjct 757 YLDIKGNHFEVLPPELGD 774
>5gqr_A B Leucine-rich repeat receptor-like protein kinase TDR
Length=598
Score = 51.2 bits (121), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 94/390 (24%), Positives = 157/390 (40%), Gaps = 38/390 (10%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL-KRS 332
T L +++ YN+ N FA L L+YF + ++ L L N+ L L +
Sbjct 194 TELQHMEIGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLPQELGNLSNLETLFLFQNG 253
Query 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
FT + +P+ S+ LK L+ L+ N + G + F+ L NL +LSL ++
Sbjct 254 FTGE------IPE----SYSNLKSLKLLDFSSNQLSGSIPSGFSTLKNLTWLSLISN--- 300
Query 393 LRTLTNETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
L+ E + P L L L N + + G LE +D+ N +
Sbjct 301 --NLSGEVPEGIGELPELTTLFLWNNNFTGVLPHKLGSNGKLETMDVSNNSFTGTIPSSL 358
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
G ++++ L N + S SL R + L + P F LRNLT +
Sbjct 359 CHG-NKLYKLILFSNMFEGELPKSLTRCESLWRFRSQNNRLNG--TIPIGFGSLRNLTFV 415
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLAR-----LWKHANPG----------GPIY 556
DLSNN + L+ L+L N R +WK N G I
Sbjct 416 DLSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPENIWKAPNLQIFSASFSNLIGEIP 475
Query 557 FLKGLSHLHILNLESNGFD-EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSL 615
G + + L+ N + IP ++ +L ++L N+LN + + S+ +
Sbjct 476 NYVGCKSFYRIELQGNSLNGTIPWDI-GHCEKLLCLNLSQNHLNGIIPWEISTLPSIADV 534
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
+L NL+T FG + + +T ++ +N
Sbjct 535 DLSHNLLTGTIPSDFGSS-KTITTFNVSYN 563
Score = 42.7 bits (99), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 141/364 (39%), Gaps = 38/364 (10%)
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
++LT+LD+ N+ P KL LKV N N L + L EL+ +
Sbjct 98 TKLTTLDISRNSFDSSFPPGISKLKFLKVFNAFSNNFEGLLPSDVSRLRFLEELNFGGSY 157
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+ + + L + L+ N L L LQ + + N E +
Sbjct 158 FEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLTELQHMEIGYNHFNGNIPSEFALL 217
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNL 253
+N LK ++S+ + P + L LFL Q G T ++ +N S++ L
Sbjct 218 SN--LKYFDVSNCSLSGSLPQELGNLSNLETLFL--FQNG--FTGEIPESYSNLKSLKLL 271
Query 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
S++QLS + + F LK NLT L L NNL+ + LP+L FL NN +
Sbjct 272 DFSSNQLSGSIPSGFSTLK--NLTWLSLISNNLSGEVPEGIGELPELTTLFLWNNNFTGV 329
Query 314 FSHSLHGLFNVRYLNLK-RSFTKQSISL------------------ASLPKIDDFSFQWL 354
H L + +++ SFT S LPK S
Sbjct 330 LPHKLGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLILFSNMFEGELPK----SLTRC 385
Query 355 KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILN 413
+ L ++N + G F L NL ++ LSN+ T++ A +P L LN
Sbjct 386 ESLWRFRSQNNRLNGTIPIGFGSLRNLTFVDLSNN-----RFTDQIPADFATAPVLQYLN 440
Query 414 LTKN 417
L+ N
Sbjct 441 LSTN 444
Score = 38.5 bits (88), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 78/325 (24%), Positives = 129/325 (40%), Gaps = 25/325 (8%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L+ LE LN + G + GL LK++ L+ + + ++ L +
Sbjct 145 LRFLEELNFGGSYFEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLT----ELQHME 200
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
+ N + F+ L +L+ D+ + L QE L N+ ++L N +
Sbjct 201 IGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLP-QELGNLSNLETLFLFQNGFTGEIP 259
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
S++ + SL+ L L S PS F L+NLT L L +NN++ + + L +L
Sbjct 260 ESYSNLKSLKLLDFSSNQLSG--SIPSGFSTLKNLTWLSLISNNLSGEVPEGIGELPELT 317
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIID 592
L L +NN + H L L +++ +N F IP + K+I
Sbjct 318 TLFLWNNNFTGVLPHK--------LGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLIL 369
Query 593 LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN------P 646
LP S+ + SL Q N + FG + RNLT +D+ N P
Sbjct 370 FSNMFEGELPKSLTRCE-SLWRFRSQNNRLNGTIPIGFG-SLRNLTFVDLSNNRFTDQIP 427
Query 647 FDCTCESIAWFVNW-INETHTNIPE 670
D + ++N N H +PE
Sbjct 428 ADFATAPVLQYLNLSTNFFHRKLPE 452
>5gr9_A B Leucine-rich repeat receptor-like protein kinase TDR
Length=599
Score = 51.2 bits (121), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 94/390 (24%), Positives = 157/390 (40%), Gaps = 38/390 (10%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL-KRS 332
T L +++ YN+ N FA L L+YF + ++ L L N+ L L +
Sbjct 195 TELQHMEIGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLPQELGNLSNLETLFLFQNG 254
Query 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
FT + +P+ S+ LK L+ L+ N + G + F+ L NL +LSL ++
Sbjct 255 FTGE------IPE----SYSNLKSLKLLDFSSNQLSGSIPSGFSTLKNLTWLSLISN--- 301
Query 393 LRTLTNETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
L+ E + P L L L N + + G LE +D+ N +
Sbjct 302 --NLSGEVPEGIGELPELTTLFLWNNNFTGVLPHKLGSNGKLETMDVSNNSFTGTIPSSL 359
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
G ++++ L N + S SL R + L + P F LRNLT +
Sbjct 360 CHG-NKLYKLILFSNMFEGELPKSLTRCESLWRFRSQNNRLNG--TIPIGFGSLRNLTFV 416
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLAR-----LWKHANPG----------GPIY 556
DLSNN + L+ L+L N R +WK N G I
Sbjct 417 DLSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPENIWKAPNLQIFSASFSNLIGEIP 476
Query 557 FLKGLSHLHILNLESNGFD-EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSL 615
G + + L+ N + IP ++ +L ++L N+LN + + S+ +
Sbjct 477 NYVGCKSFYRIELQGNSLNGTIPWDI-GHCEKLLCLNLSQNHLNGIIPWEISTLPSIADV 535
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
+L NL+T FG + + +T ++ +N
Sbjct 536 DLSHNLLTGTIPSDFGSS-KTITTFNVSYN 564
Score = 42.7 bits (99), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 141/364 (39%), Gaps = 38/364 (10%)
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
++LT+LD+ N+ P KL LKV N N L + L EL+ +
Sbjct 99 TKLTTLDISRNSFDSSFPPGISKLKFLKVFNAFSNNFEGLLPSDVSRLRFLEELNFGGSY 158
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+ + + L + L+ N L L LQ + + N E +
Sbjct 159 FEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLTELQHMEIGYNHFNGNIPSEFALL 218
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNL 253
+N LK ++S+ + P + L LFL Q G T ++ +N S++ L
Sbjct 219 SN--LKYFDVSNCSLSGSLPQELGNLSNLETLFL--FQNG--FTGEIPESYSNLKSLKLL 272
Query 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
S++QLS + + F LK NLT L L NNL+ + LP+L FL NN +
Sbjct 273 DFSSNQLSGSIPSGFSTLK--NLTWLSLISNNLSGEVPEGIGELPELTTLFLWNNNFTGV 330
Query 314 FSHSLHGLFNVRYLNLK-RSFTKQSISL------------------ASLPKIDDFSFQWL 354
H L + +++ SFT S LPK S
Sbjct 331 LPHKLGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLILFSNMFEGELPK----SLTRC 386
Query 355 KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILN 413
+ L ++N + G F L NL ++ LSN+ T++ A +P L LN
Sbjct 387 ESLWRFRSQNNRLNGTIPIGFGSLRNLTFVDLSNN-----RFTDQIPADFATAPVLQYLN 441
Query 414 LTKN 417
L+ N
Sbjct 442 LSTN 445
Score = 38.5 bits (88), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 78/325 (24%), Positives = 129/325 (40%), Gaps = 25/325 (8%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L+ LE LN + G + GL LK++ L+ + + ++ L +
Sbjct 146 LRFLEELNFGGSYFEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLT----ELQHME 201
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
+ N + F+ L +L+ D+ + L QE L N+ ++L N +
Sbjct 202 IGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLP-QELGNLSNLETLFLFQNGFTGEIP 260
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
S++ + SL+ L L S PS F L+NLT L L +NN++ + + L +L
Sbjct 261 ESYSNLKSLKLLDFSSNQLSG--SIPSGFSTLKNLTWLSLISNNLSGEVPEGIGELPELT 318
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIID 592
L L +NN + H L L +++ +N F IP + K+I
Sbjct 319 TLFLWNNNFTGVLPHK--------LGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLIL 370
Query 593 LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN------P 646
LP S+ + SL Q N + FG + RNLT +D+ N P
Sbjct 371 FSNMFEGELPKSLTRCE-SLWRFRSQNNRLNGTIPIGFG-SLRNLTFVDLSNNRFTDQIP 428
Query 647 FDCTCESIAWFVNW-INETHTNIPE 670
D + ++N N H +PE
Sbjct 429 ADFATAPVLQYLNLSTNFFHRKLPE 453
>2omu_A A Internalin-A
Length=462
Score = 50.8 bits (120), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 93/345 (27%), Positives = 144/345 (42%), Gaps = 57/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L N ++ L+P L L+ L++ N+
Sbjct 129 TNLNRLELSSNTISDISA--LSGLTSLQQLSFSSNQVTDLKP--LANLTTLERLDISSNK 184
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 185 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 238
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 239 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 282
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 283 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 321
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 322 --PVSSLTKLQRLFFSNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 377
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 378 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 420
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 68/239 (28%), Positives = 100/239 (42%), Gaps = 56/239 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETFVSLAHSPLHIL 412
L L L + N I I + +GL +L+ LS S N T L+ L N T L L
Sbjct 128 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFSSNQVTDLKPLANLTT-------LERL 178
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+++ NK+S I + L +LE L N+I ++T
Sbjct 179 DISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------ 211
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKL 532
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 212 --PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKL 263
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 264 TELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 312
>2omv_A A Internalin-A
Length=461
Score = 50.8 bits (120), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 146/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L+ G N ++ L+P L L+ L++ N+
Sbjct 129 TNLNRLELSSNTISDISA--LSGLTSLQQLNFG-NQVTDLKP--LANLTTLERLDISSNK 183
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 184 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 237
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 238 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 281
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 282 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 320
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 321 --PVSSLTKLQRLFFSNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 376
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 377 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 419
Score = 41.2 bits (95), Expect = 0.053, Method: Compositional matrix adjust.
Identities = 66/238 (28%), Positives = 99/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ L+ N T L+ L N T L L+
Sbjct 128 LTNLNRLELSSNTISDISA--LSGLTSLQQLNFGNQVTDLKPLANLTT-------LERLD 178
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 179 ISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------- 210
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 211 -PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKLT 263
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 264 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 311
>2omw_A A Internalin-A
Length=461
Score = 50.8 bits (120), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 146/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L+ G N ++ L+P L L+ L++ N+
Sbjct 129 TNLNRLELSSNTISDISA--LSGLTSLQQLNFG-NQVTDLKP--LANLTTLERLDISSNK 183
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 184 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 237
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 238 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 281
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 282 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 320
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 321 --PVSSLTKLQRLFFSNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 376
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 377 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 419
Score = 41.2 bits (95), Expect = 0.053, Method: Compositional matrix adjust.
Identities = 66/238 (28%), Positives = 99/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ L+ N T L+ L N T L L+
Sbjct 128 LTNLNRLELSSNTISDISA--LSGLTSLQQLNFGNQVTDLKPLANLTT-------LERLD 178
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 179 ISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------- 210
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 211 -PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKLT 263
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 264 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 311
>7d2s_A A Ras suppressor protein 1
Length=220
Score = 49.3 bits (116), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 55/177 (31%), Positives = 85/177 (48%), Gaps = 18/177 (10%)
Query 18 GMLCASSTTKCTVSHEVADCSHLKLTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYS 75
G+ S T+ +SH KLT VP ++ N+ VLN +NQ+ LP +
Sbjct 40 GLFTLSHITQLVLSHN-------KLTMVPPNIAELKNLEVLNFFNNQIEELPTQ-ISSLQ 91
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLS-DKTFAFCTNLTELHLMSNS 134
+L L++G N ++ L P LP L+VL+L +N LS+ S F + T L L+L N
Sbjct 92 KLKHLNLGMNRLNTL-PRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDND 150
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSS--TKLGTQVQLENLQELLLSNNKIQALKSE 189
+ + + K L L L N L S ++G +L L+EL + N++ L E
Sbjct 151 FEILPPD-IGKLTKLQILSLRDNDLISLPKEIG---ELTQLKELHIQGNRLTVLPPE 203
>2omx_A A Internalin-A
Length=462
Score = 50.8 bits (120), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 93/345 (27%), Positives = 145/345 (42%), Gaps = 57/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L+ N ++ L+P L L+ L++ N+
Sbjct 129 TNLNRLELSSNTISDISA--LSGLTSLQQLNFSSNQVTDLKP--LANLTTLERLDISSNK 184
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 185 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 238
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 239 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 282
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 283 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 321
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 322 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 377
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 378 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 420
Score = 39.3 bits (90), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 60/215 (28%), Positives = 97/215 (45%), Gaps = 32/215 (15%)
Query 378 LINLKYLSLS-NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVL 436
L NL L LS N+ + + L+ T L LN + N+++ ++ + L LE L
Sbjct 128 LTNLNRLELSSNTISDISALSGLT-------SLQQLNFSSNQVTDLK--PLANLTTLERL 178
Query 437 DLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVD 496
D+ N++ + LE++ + N+ +T ++ +L L L LK++
Sbjct 179 DISSNKVSDISVLAKLTNLESLIA---TNNQISDIT--PLGILTNLDELSLNGNQLKDIG 233
Query 497 SSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIY 556
+ L NLT LDL+NN I+N+ L GL KL L L N ++ I
Sbjct 234 T----LASLTNLTDLDLANNQISNL--APLSGLTKLTELKLGANQISN----------IS 277
Query 557 FLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L GL+ L L L N ++I P+ K+L L +
Sbjct 278 PLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 312
Score = 34.3 bits (77), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 68/242 (28%), Positives = 108/242 (45%), Gaps = 44/242 (18%)
Query 424 SDAFSWLGHLEVLDLGLNEIG-QELTGQEWRGLENIFEIYLSYNKYLQLT--RNSFALVP 480
+D S +V L + +G + + G E+ L N+ +I S N+ +T +N LV
Sbjct 32 TDTVSQTDLDQVTTLQADRLGIKSIDGVEY--LNNLTQINFSNNQLTDITPLKNLTKLV- 88
Query 481 SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHN 540
+++ + ++ +P L NLT L L NN I +I D L+ L L L+L N
Sbjct 89 ---DILMNNNQIADI----TPLANLTNLTGLTLFNNQITDI--DPLKNLTNLNRLELSSN 139
Query 541 NLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFEL-----KIIDLG 594
++ I L GL+ L LN SN ++ P+ L L K+ D+
Sbjct 140 TISD----------ISALSGLTSLQQLNFSSNQVTDLKPLANLTTLERLDISSNKVSDIS 189
Query 595 ----LNNLNTLPASVFNNQVS-LKSLNLQKNL----ITSVEKKVFG--PAFRNLTELDMR 643
L NL +L A+ NNQ+S + L + NL + + K G + NLT+LD+
Sbjct 190 VLAKLTNLESLIAT--NNQISDITPLGILTNLDELSLNGNQLKDIGTLASLTNLTDLDLA 247
Query 644 FN 645
N
Sbjct 248 NN 249
>4mna_A A LRR receptor-like serine/threonine-protein kinase FLS2
Length=662
Score = 51.2 bits (121), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 152/600 (25%), Positives = 244/600 (41%), Gaps = 106/600 (18%)
Query 30 VSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISK 89
+ E+ +CS L L L NQL A QL +L + N ++
Sbjct 112 IPAEIGNCSSL-------------VQLELYDNQLTGKIPAELGNLVQLQALRIYKNKLTS 158
Query 90 LEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNL 149
P +L L L L N L + F +L L L SN+ +NL
Sbjct 159 SIPSSLFRLTQLTHLGLSENHLVGPISEEIGFLESLEVLTLHSNNFTGEFPQSITNLRNL 218
Query 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
L + N +S L NL+ L +N + I + LK L+LS NQ+
Sbjct 219 TVLTVGFNNISGELPADLGLLTNLRNLSAHDNLLTGPIPSS--ISNCTGLKLLDLSHNQM 276
Query 210 KEFSPGCFHAIGRLFGLFLNNVQLGPS-LTEKLCLELANTS-IRNLSLSNSQLSTTSNTT 267
P F + F + +G + T ++ ++ N S + LS++++ L+ T
Sbjct 277 TGEIPRGFGRMNLTF------ISIGRNHFTGEIPDDIFNCSNLETLSVADNNLTGTLK-P 329
Query 268 FLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
+G K L +L +SYN+L +P+ E N++ L N+ YL
Sbjct 330 LIG-KLQKLRILQVSYNSLT-------GPIPR------EIGNLKDL---------NILYL 366
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPG-IKSNMFTGLINLKYLSL 386
+ FT + +P+ L L+ L M ND+ G I MF + L L L
Sbjct 367 H-SNGFTGR------IPR----EMSNLTLLQGLRMYSNDLEGPIPEEMFDMKL-LSVLDL 414
Query 387 SNS---------FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLD 437
SN+ F+ L +LT L+L NK + + L L D
Sbjct 415 SNNKFSGQIPALFSKLESLT-------------YLSLQGNKFNGSIPASLKSLSLLNTFD 461
Query 438 LGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVP-SLQRL-MLRRVALKN- 494
+ N + + G+ L+N+ ++YL+++ L LT +P L +L M++ + L N
Sbjct 462 ISDNLLTGTIPGELLASLKNM-QLYLNFSNNL-LT----GTIPKELGKLEMVQEIDLSNN 515
Query 495 --VDSSPSPFQPLRNLTILDLSNNNIAN-INDDMLEGLEKLEILDLQHNNLARLWKHANP 551
S P Q +N+ LD S NN++ I D++ +G++ + L+L N+ + +
Sbjct 516 LFSGSIPRSLQACKNVFTLDFSQNNLSGHIPDEVFQGMDMIISLNLSRNSFSGEIPQS-- 573
Query 552 GGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLNNLNT-LPAS-VFNN 608
++HL L+L SN EIP E +L LK + L NNL +P S VF N
Sbjct 574 ------FGNMTHLVSLDLSSNNLTGEIP-ESLANLSTLKHLKLASNNLKGHVPESGVFKN 626
Score = 43.9 bits (102), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 148/604 (25%), Positives = 233/604 (39%), Gaps = 39/604 (6%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+ H T + D ++ ++L QL + + + L LD+ N+ + P
Sbjct 31 IGSLRHCNWTGITCDSTGHVVSVSLLEKQLEGVLSPAIANLTYLQVLDLTSNSFTGKIPA 90
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
KL L+ L L N L C++L +L L N + L L
Sbjct 91 EIGKLTELQSLVLTENLLEGDIPAEIGNCSSLVQLELYDNQLTGKIPAELGNLVQLQALR 150
Query 154 LSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
+ N L+S+ + +L L L LS N + SEE+ SL+ L L SN
Sbjct 151 IYKNKLTSSIPSSLFRLTQLTHLGLSENHLVGPISEEIGFL--ESLEVLTLHSNNFTGEF 208
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKW 273
P + L L + + L L L T++RNLS ++ L+ ++
Sbjct 209 PQSITNLRNLTVLTVGFNNISGELPADLGLL---TNLRNLSAHDNLLTGPIPSSIS--NC 263
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL-----N 328
T L +LDLS+N + F + L + + N+ + N+ L N
Sbjct 264 TGLKLLDLSHNQMTGEIPRGFGRM-NLTFISIGRNHFTGEIPDDIFNCSNLETLSVADNN 322
Query 329 LKRSFTKQSISLASLPKIDDFSFQWLKC---LEHLNMEDNDIPGIKSNMFTGLINLKYLS 385
L + L L +I S+ L E N++D +I + SN FTG I + +
Sbjct 323 LTGTLKPLIGKLQKL-RILQVSYNSLTGPIPREIGNLKDLNILYLHSNGFTGRIPREMSN 381
Query 386 LSNSFTSLRTLTNETFVSLAHSP-----LHILNLTKNKISKIESDAFSWLGHLEVLDLGL 440
L+ LR +N+ + L +L+L+ NK S FS L L L L
Sbjct 382 LT-LLQGLRMYSNDLEGPIPEEMFDMKLLSVLDLSNNKFSGQIPALFSKLESLTYLSLQG 440
Query 441 NEIGQELTGQ-EWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV--DS 497
N+ + + L N F+I + L L+ SL+ + L N+ +
Sbjct 441 NKFNGSIPASLKSLSLLNTFDI----SDNLLTGTIPGELLASLKNMQLYLNFSNNLLTGT 496
Query 498 SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF 557
P L + +DLSNN + L+ + + LD NNL+ H P
Sbjct 497 IPKELGKLEMVQEIDLSNNLFSGSIPRSLQACKNVFTLDFSQNNLS---GHI----PDEV 549
Query 558 LKGLSHLHILNLESNGFD-EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
+G+ + LNL N F EIP + F ++ L +DL NNL N +LK L
Sbjct 550 FQGMDMIISLNLSRNSFSGEIP-QSFGNMTHLVSLDLSSNNLTGEIPESLANLSTLKHLK 608
Query 617 LQKN 620
L N
Sbjct 609 LASN 612
>6fnw_A A Volume-regulated anion channel subunit LRRC8A
Length=417
Score = 50.4 bits (119), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 197 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 255
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 256 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 312
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 313 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 352
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 191 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 247
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 248 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 297
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 298 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 356
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 357 -GELTNLTQIELRGNRLEC 374
>4y61_B B SLIT and NTRK-like protein 2
Length=272
Score = 49.7 bits (117), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 56/228 (25%), Positives = 97/228 (43%), Gaps = 40/228 (18%)
Query 458 IFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNN 517
I++++L+ N +L N F + L L L+ + P F L+ L L L+NN
Sbjct 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEI--RPGAFSGLKTLKRLHLNNNK 121
Query 518 IANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI 577
+ + +D GLE LE L +N +I +E+ F +
Sbjct 122 LEVLREDTFLGLESLEYLQADYN------------------------YISTIEAGAFSK- 156
Query 578 PVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNL 637
L +LK++ L N L +LP++VF V L L+L+ N + + +
Sbjct 157 -------LNKLKVLILNDNLLLSLPSNVF-RFVLLTHLDLRGNRLKVMPFAGVLEHIGGI 208
Query 638 TELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYLCNTPPHYHG 685
E+ + NP++CTC+ + W++ + E+ +C TP HG
Sbjct 209 MEIQLEENPWNCTCDLLP-LKAWLDTITVFVGEI----VCETPFRLHG 251
Score = 48.5 bits (114), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 33/104 (32%), Positives = 52/104 (50%), Gaps = 2/104 (2%)
Query 127 ELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQAL 186
+L L N + ++ N FV N +TL L +NGL + G L+ L+ L L+NNK++ L
Sbjct 66 QLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRPGAFSGLKTLKRLHLNNNKLEVL 125
Query 187 KSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
+ + SL+ L+ N I G F + +L L LN+
Sbjct 126 RED--TFLGLESLEYLQADYNYISTIEAGAFSKLNKLKVLILND 167
Score = 42.4 bits (98), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 43/142 (30%), Positives = 59/142 (42%), Gaps = 3/142 (2%)
Query 20 LCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTS 79
LC ++ E + + L Q P I L L N L RL F YS +
Sbjct 34 LCEEKENVLNINCENKGFTTVSLLQPPQ---YRIYQLFLNGNLLTRLYPNEFVNYSNAVT 90
Query 80 LDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIK 139
L +G N + ++ P L LK L+L +N+L L + TF +L L N I I+
Sbjct 91 LHLGNNGLQEIRPGAFSGLKTLKRLHLNNNKLEVLREDTFLGLESLEYLQADYNYISTIE 150
Query 140 NNPFVKQKNLITLDLSHNGLSS 161
F K L L L+ N L S
Sbjct 151 AGAFSKLNKLKVLILNDNLLLS 172
Score = 34.7 bits (78), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 50/159 (31%), Positives = 69/159 (43%), Gaps = 20/159 (13%)
Query 222 RLFGLFLNNVQLGPSLTEKLCLELANTS-IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLD 280
R++ LFLN G LT E N S L L N+ L F GLK L L
Sbjct 63 RIYQLFLN----GNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRPGAFSGLK--TLKRLH 116
Query 281 LSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISL 340
L+ N L V+ D+F L LEY +YN I + + + L ++ L L + L
Sbjct 117 LNNNKLEVLREDTFLGLESLEYLQADYNYISTIEAGAFSKLNKLKVLILNDNL------L 170
Query 341 ASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLI 379
SLP + F F L HL++ N +K F G++
Sbjct 171 LSLPS-NVFRFVLLT---HLDLRGNR---LKVMPFAGVL 202
Score = 34.7 bits (78), Expect = 4.1, Method: Compositional matrix adjust.
Identities = 35/164 (21%), Positives = 71/164 (43%), Gaps = 32/164 (20%)
Query 145 KQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLEL 204
+++N++ ++ + G ++ L Q + +L L+ N + L E ++N+ L L
Sbjct 37 EKENVLNINCENKGFTTVSLLQPPQYR-IYQLFLNGNLLTRLYPNEFVNYSNAV--TLHL 93
Query 205 SSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTS 264
+N ++E PG F + +++ L L+N++L
Sbjct 94 GNNGLQEIRPGAFSGL---------------------------KTLKRLHLNNNKLEVLR 126
Query 265 NTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
TFLGL+ +L L YN ++ + +F+ L +L+ L N
Sbjct 127 EDTFLGLE--SLEYLQADYNYISTIEAGAFSKLNKLKVLILNDN 168
>4q3g_B B OsSERK2
Length=244
Score = 49.3 bits (116), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 42/160 (26%), Positives = 74/160 (46%), Gaps = 9/160 (6%)
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
P ++ +DL N ++ L L+ L+ L+L NN++ G L L++
Sbjct 44 PDNSVIRVDLGNAQLSGALVPQLGQLKNLQYLELYSNNIS--------GTIPNELGNLTN 95
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L L+L N F E L++L+ + L N+L+ N +L+ L L N +
Sbjct 96 LVSLDLYLNNFTGFIPETLGQLYKLRFLRLNNNSLSGSIPKSLTNITTLQELALDTNQLK 155
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 156 SVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 194
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 33/105 (31%), Positives = 50/105 (48%), Gaps = 2/105 (2%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
NL L L SN+I N NL++LDL N + T QL L+ L L+NN +
Sbjct 71 NLQYLELYSNNISGTIPNELGNLTNLVSLDLYLNNFTGFIPETLGQLYKLRFLRLNNNSL 130
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+ L ++L++L L +NQ+K G F + L ++L
Sbjct 131 SGSIPKSLTNI--TTLQELALDTNQLKSVPDGIFDRLTSLQKIWL 173
Score = 33.9 bits (76), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 37/120 (31%), Positives = 55/120 (46%), Gaps = 5/120 (4%)
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
+I +DL + LS + QL+NLQ L L +N I EL N L L+L N
Sbjct 48 VIRVDLGNAQLSGALVPQLGQLKNLQYLELYSNNISGTIPNELGNLTN--LVSLDLYLNN 105
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
F P + +L L LNN L S+ + L T+++ L+L +QL + + F
Sbjct 106 FTGFIPETLGQLYKLRFLRLNNNSLSGSIPKSLT---NITTLQELALDTNQLKSVPDGIF 162
Score = 33.5 bits (75), Expect = 8.9, Method: Compositional matrix adjust.
Identities = 26/92 (28%), Positives = 40/92 (43%), Gaps = 0/92 (0%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L L N + + L SLD+ N + PE +L L+ L L +N L
Sbjct 71 NLQYLELYSNNISGTIPNELGNLTNLVSLDLYLNNFTGFIPETLGQLYKLRFLRLNNNSL 130
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
S K+ T L EL L +N ++ + + F
Sbjct 131 SGSIPKSLTNITTLQELALDTNQLKSVPDGIF 162
>7y1r_C E Transforming growth factor beta activator LRRC33
Length=656
Score = 50.4 bits (119), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 61/212 (29%), Positives = 90/212 (42%), Gaps = 34/212 (16%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L+L + +I AF GHL L LG N + EN E
Sbjct 81 LESLSLHSCHLERISRGAFQEQGHLRSLVLGDNCLS-----------ENYEE-------- 121
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
T + +P L+RL L AL D + Q L +L + L+ N I ++D + EG
Sbjct 122 ---TAAALHALPGLRRLDLSGNALTE-DMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEG 177
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
LE+L LDLQ N + + A GL+ L LNL F+ +P V L L
Sbjct 178 LERLRELDLQRNYIFEIEGGA--------FDGLAELRHLNL---AFNNLPCIVDFGLTRL 226
Query 589 KIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
+++++ N L A+ L++L+L N
Sbjct 227 RVLNVSYNVLEWFLATGGEAAFELETLDLSHN 258
Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 46/171 (27%), Positives = 75/171 (44%), Gaps = 17/171 (10%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
++ L+++ NQ + LP + L+ L++ N + L + L L+L HN+
Sbjct 326 ADLRFLDMSQNQFQYLPDGFLRKMPSLSHLNLHQNCLMTLHIREHEPPGALTELDLSHNQ 385
Query 111 LSQLS-DKTFAFC-TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV 168
LS+L A C +L +L SN + + F +N+ TLD+SHN +S L
Sbjct 386 LSELHLAPGLASCLGSLRLFNLSSNQLLGVPPGLFANARNITTLDMSHNQISLCPLPXXX 445
Query 169 ------------QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
+ +L+ L L + AL F +SL L+LSSN
Sbjct 446 XXXXXXXXXXFRNMASLRSLSLEGCGLGALPDCP---FQGTSLTYLDLSSN 493
Score = 42.7 bits (99), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 76/287 (26%), Positives = 111/287 (39%), Gaps = 52/287 (18%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
ADC L VP LP + +L L N L+ L + Y L SL + + ++
Sbjct 38 AADCRGQSLASVPSSLPPHARMLTLDANPLKTLWNHSLQPYPLLESLSLHSCHLERISRG 97
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
Q+ L+ L L N LS+ ++T A LH + L LD
Sbjct 98 AFQEQGHLRSLVLGDNCLSENYEETAA------ALHAL---------------PGLRRLD 136
Query 154 LSHNGLSSTKLGTQVQ-LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
LS N L+ +Q L +L+ + L+ N I L + L++L+L N I E
Sbjct 137 LSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEGL--ERLRELDLQRNYIFEI 194
Query 213 SPGCFHAIGRL--FGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQ----LSTTSNT 266
G F + L L NN+ ++ T +R L++S + L+T
Sbjct 195 EGGAFDGLAELRHLNLAFNNL--------PCIVDFGLTRLRVLNVSYNVLEWFLATGGEA 246
Query 267 TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQ---LEYFFLEYNNI 310
F L LDLS+N L F LPQ L L NN+
Sbjct 247 AF------ELETLDLSHNQLLF-----FPLLPQYSKLRTLLLRDNNM 282
Score = 38.5 bits (88), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 28/96 (29%), Positives = 43/96 (45%), Gaps = 2/96 (2%)
Query 558 LKGLSHLHILNLESNGFDE-IPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLN 616
L L L L+L N E + + ++L L+ + L N + L SVF L+ L+
Sbjct 126 LHALPGLRRLDLSGNALTEDMAALMLQNLSSLRSVSLAGNTIMRLDDSVFEGLERLRELD 185
Query 617 LQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCE 652
LQ+N I +E F L L++ FN C +
Sbjct 186 LQRNYIFEIEGGAFD-GLAELRHLNLAFNNLPCIVD 220
Score = 37.4 bits (85), Expect = 0.82, Method: Compositional matrix adjust.
Identities = 32/110 (29%), Positives = 57/110 (52%), Gaps = 9/110 (8%)
Query 336 QSISLA--SLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSL 393
+S+SLA ++ ++DD F+ L+ L L+++ N I I+ F GL L++L+L +F +L
Sbjct 158 RSVSLAGNTIMRLDDSVFEGLERLRELDLQRNYIFEIEGGAFDGLAELRHLNL--AFNNL 215
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEI 443
V + L +LN++ N + + LE LDL N++
Sbjct 216 -----PCIVDFGLTRLRVLNVSYNVLEWFLATGGEAAFELETLDLSHNQL 260
Score = 35.4 bits (80), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 51/188 (27%), Positives = 77/188 (41%), Gaps = 26/188 (14%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
L+ L++ N+ L D +L+ L+L N + + L LDLSHN LS
Sbjct 328 LRFLDMSQNQFQYLPDGFLRKMPSLSHLNLHQNCLMTLHIREHEPPGALTELDLSHNQLS 387
Query 161 STKL--GTQVQLENLQELLLSNNKIQALKSEELDIFANS-SLKKLELSSNQIKEFS-PGC 216
L G L +L+ LS+N++ + +FAN+ ++ L++S NQI P
Sbjct 388 ELHLAPGLASCLGSLRLFNLSSNQLLGVPP---GLFANARNITTLDMSHNQISLCPLPXX 444
Query 217 FHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNL 276
N+ S+R+LSL L + F G T+L
Sbjct 445 XXXXXXXXXXXFRNM----------------ASLRSLSLEGCGLGALPDCPFQG---TSL 485
Query 277 TMLDLSYN 284
T LDLS N
Sbjct 486 TYLDLSSN 493
>8f75_B B Volume-regulated anion channel subunit LRRC8A
Length=729
Score = 50.8 bits (120), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 501 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 559
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 560 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 616
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 617 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 656
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 495 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 551
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 552 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 601
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 602 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 660
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 661 -GELTNLTQIELRGNRLEC 678
>8f75_A A Volume-regulated anion channel subunit LRRC8A
Length=729
Score = 50.8 bits (120), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 501 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 559
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 560 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 616
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 617 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 656
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 495 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 551
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 552 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 601
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 602 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 660
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 661 -GELTNLTQIELRGNRLEC 678
>8f7e_A B Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 838
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8f7j_A E Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 838
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8f7e_B C Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 838
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8dra_A A Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 838
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8f7d_A A Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 838
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8dro_A B Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 838
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8drn_A A Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 838
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8dro_B C Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 838
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8drq_A E Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 838
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>8dra_B B Volume-regulated anion channel subunit LRRC8A,Soluble
cytochrome b562
Length=911
Score = 50.8 bits (120), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 53/165 (32%), Positives = 84/165 (51%), Gaps = 12/165 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
N+T L L L R+P + F+ ++ L +D+ N + +E + Q L L L L +N
Sbjct 683 VNLTELELIRCDLERIPHSIFSLHN-LQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 741
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + TNL L+L N I+KI F +K L LDLSHN L+ +G
Sbjct 742 HIAYIPIQ-IGNLTNLERLYLNRNKIEKIPTQLFYCRK-LRYLDLSHNNLTFLPADIGL- 798
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
L+NLQ L ++ N+I+AL E +F L+ L L +N ++
Sbjct 799 --LQNLQNLAVTANRIEALPPE---LFQCRKLRALHLGNNVLQSL 838
Score = 45.1 bits (105), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 55/199 (28%), Positives = 95/199 (48%), Gaps = 38/199 (19%)
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM-LEGLEKL 532
NS + +L L L R L+ + P L NL +DL +NN+ I + + + L +L
Sbjct 677 NSLKKMVNLTELELIRCDLERI---PHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRL 733
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIID 592
L L +N++A + PI + L++L L L N ++IP ++F +L+ +D
Sbjct 734 TCLKLWYNHIAYI--------PIQ-IGNLTNLERLYLNRNKIEKIPTQLFY-CRKLRYLD 783
Query 593 LGLNNLNTLPA-----------SVFNNQV-----------SLKSLNLQKNLITSVEKKVF 630
L NNL LPA +V N++ L++L+L N++ S+ +V
Sbjct 784 LSHNNLTFLPADIGLLQNLQNLAVTANRIEALPPELFQCRKLRALHLGNNVLQSLPSRV- 842
Query 631 GPAFRNLTELDMRFNPFDC 649
NLT++++R N +C
Sbjct 843 -GELTNLTQIELRGNRLEC 860
>4q3g_A A OsSERK2
Length=244
Score = 48.9 bits (115), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 42/160 (26%), Positives = 74/160 (46%), Gaps = 9/160 (6%)
Query 504 PLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSH 563
P ++ +DL N ++ L L+ L+ L+L NN++ G L L++
Sbjct 44 PDNSVIRVDLGNAQLSGALVPQLGQLKNLQYLELYSNNIS--------GTIPNELGNLTN 95
Query 564 LHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLIT 623
L L+L N F E L++L+ + L N+L+ N +L+ L L N +
Sbjct 96 LVSLDLYLNNFTGFIPETLGQLYKLRFLRLNNNSLSGSIPKSLTNITTLQELALDTNQLK 155
Query 624 SVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 156 SVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 194
Score = 36.2 bits (82), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 33/105 (31%), Positives = 50/105 (48%), Gaps = 2/105 (2%)
Query 124 NLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKI 183
NL L L SN+I N NL++LDL N + T QL L+ L L+NN +
Sbjct 71 NLQYLELYSNNISGTIPNELGNLTNLVSLDLYLNNFTGFIPETLGQLYKLRFLRLNNNSL 130
Query 184 QALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+ L ++L++L L +NQ+K G F + L ++L
Sbjct 131 SGSIPKSLTNI--TTLQELALDTNQLKSVPDGIFDRLTSLQKIWL 173
Score = 33.9 bits (76), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 37/120 (31%), Positives = 55/120 (46%), Gaps = 5/120 (4%)
Query 149 LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
+I +DL + LS + QL+NLQ L L +N I EL N L L+L N
Sbjct 48 VIRVDLGNAQLSGALVPQLGQLKNLQYLELYSNNISGTIPNELGNLTN--LVSLDLYLNN 105
Query 209 IKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTF 268
F P + +L L LNN L S+ + L T+++ L+L +QL + + F
Sbjct 106 FTGFIPETLGQLYKLRFLRLNNNSLSGSIPKSLT---NITTLQELALDTNQLKSVPDGIF 162
Score = 33.5 bits (75), Expect = 8.9, Method: Compositional matrix adjust.
Identities = 26/94 (28%), Positives = 41/94 (44%), Gaps = 0/94 (0%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L L N + + L SLD+ N + PE +L L+ L L +N L
Sbjct 71 NLQYLELYSNNISGTIPNELGNLTNLVSLDLYLNNFTGFIPETLGQLYKLRFLRLNNNSL 130
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
S K+ T L EL L +N ++ + + F +
Sbjct 131 SGSIPKSLTNITTLQELALDTNQLKSVPDGIFDR 164
>2omt_A A Internalin-A
Length=462
Score = 50.1 bits (118), Expect = 8e-05, Method: Compositional matrix adjust.
Identities = 93/345 (27%), Positives = 144/345 (42%), Gaps = 57/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L N ++ L+P L L+ L++ N+
Sbjct 129 TNLNRLELSSNTISDISA--LSGLTSLQQLSFSSNQVTDLKP--LANLTTLERLDISSNK 184
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 185 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 238
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 239 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 282
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 283 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 321
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 322 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 377
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 378 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 420
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 68/239 (28%), Positives = 100/239 (42%), Gaps = 56/239 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLTNETFVSLAHSPLHIL 412
L L L + N I I + +GL +L+ LS S N T L+ L N T L L
Sbjct 128 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFSSNQVTDLKPLANLTT-------LERL 178
Query 413 NLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLT 472
+++ NK+S I + L +LE L N+I ++T
Sbjct 179 DISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------ 211
Query 473 RNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKL 532
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 212 --PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKL 263
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 264 TELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 312
>2omy_A A Internalin-A
Length=461
Score = 50.1 bits (118), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 146/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L+ G N ++ L+P L L+ L++ N+
Sbjct 129 TNLNRLELSSNTISDISA--LSGLTSLQQLNFG-NQVTDLKP--LANLTTLERLDISSNK 183
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 184 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 237
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 238 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 281
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 282 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 320
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 321 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 376
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 377 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 419
Score = 41.2 bits (95), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 67/238 (28%), Positives = 100/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ L+ N T L+ L N T L L+
Sbjct 128 LTNLNRLELSSNTISDISA--LSGLTSLQQLNFGNQVTDLKPLANLTT-------LERLD 178
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 179 ISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------- 210
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + S L NLT LDL+NN I+N+ L GL KL
Sbjct 211 -PLGILTNLDELSLNGNQLKDIGTLAS----LTNLTDLDLANNQISNL--APLSGLTKLT 263
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 264 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 311
>2omz_A A Internalin-A
Length=466
Score = 50.1 bits (118), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 145/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L G N ++ L+P L L+ L++ N+
Sbjct 133 TNLNRLELSSNTISDISA--LSGLTSLQQLSFG-NQVTDLKP--LANLTTLERLDISSNK 187
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 188 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 241
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 242 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 285
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 286 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 324
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 325 --PVSSLTKLQRLFFANNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 380
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 381 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 423
Score = 42.4 bits (98), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 67/238 (28%), Positives = 99/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ LS N T L+ L N T L L+
Sbjct 132 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFGNQVTDLKPLANLTT-------LERLD 182
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 183 ISSNKVSDIS--VLAKLTNLESLIATNNQI-SDIT------------------------- 214
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 215 -PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKLT 267
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 268 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 315
>5gij_A B Leucine-rich repeat receptor-like protein kinase TDR
Length=607
Score = 50.1 bits (118), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 94/390 (24%), Positives = 157/390 (40%), Gaps = 38/390 (10%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL-KRS 332
T L +++ YN+ N FA L L+YF + ++ L L N+ L L +
Sbjct 195 TELQHMEIGYNHFNGNIPSEFALLSNLKYFDVSNASLSGSLPQELGNLSNLETLFLFQNG 254
Query 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
FT + +P+ S+ LK L+ L+ N + G + F+ L NL +LSL ++
Sbjct 255 FTGE------IPE----SYSNLKSLKLLDFSSNQLSGSIPSGFSTLKNLTWLSLISN--- 301
Query 393 LRTLTNETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
L+ E + P L L L N + + G LE +D+ N +
Sbjct 302 --NLSGEVPEGIGELPELTTLFLWNNNFTGVLPHKLGSNGKLETMDVSNNSFTGTIPSSL 359
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
G ++++ L N + S SL R + L + P F LRNLT +
Sbjct 360 CHG-NKLYKLILFSNMFEGELPKSLTRCESLWRFRSQNNRLNG--TIPIGFGSLRNLTFV 416
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLAR-----LWKHANPG----------GPIY 556
DLSNN + L+ L+L N R +WK N G I
Sbjct 417 DLSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPENIWKAPNLQIFSASFSNLIGEIP 476
Query 557 FLKGLSHLHILNLESNGFD-EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSL 615
G + + L+ N + IP ++ +L ++L N+LN + + S+ +
Sbjct 477 NYVGCKSFYRIELQGNSLNGTIPWDI-GHCEKLLSLNLSQNHLNGIIPWEISTLPSIADV 535
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
+L NL+T FG + + +T ++ +N
Sbjct 536 DLSHNLLTGTIPSDFGSS-KTITTFNVSYN 564
Score = 42.7 bits (99), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 141/364 (39%), Gaps = 38/364 (10%)
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
++LT+LD+ N+ P KL LKV N N L + L EL+ +
Sbjct 99 TKLTTLDISRNSFDSSFPPGISKLKFLKVFNAFSNNFEGLLPSDVSRLRFLEELNFGGSY 158
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+ + + L + L+ N L L LQ + + N E +
Sbjct 159 FEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLTELQHMEIGYNHFNGNIPSEFALL 218
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNL 253
+N LK ++S+ + P + L LFL Q G T ++ +N S++ L
Sbjct 219 SN--LKYFDVSNASLSGSLPQELGNLSNLETLFL--FQNG--FTGEIPESYSNLKSLKLL 272
Query 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
S++QLS + + F LK NLT L L NNL+ + LP+L FL NN +
Sbjct 273 DFSSNQLSGSIPSGFSTLK--NLTWLSLISNNLSGEVPEGIGELPELTTLFLWNNNFTGV 330
Query 314 FSHSLHGLFNVRYLNLK-RSFTKQSISL------------------ASLPKIDDFSFQWL 354
H L + +++ SFT S LPK S
Sbjct 331 LPHKLGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLILFSNMFEGELPK----SLTRC 386
Query 355 KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILN 413
+ L ++N + G F L NL ++ LSN+ T++ A +P L LN
Sbjct 387 ESLWRFRSQNNRLNGTIPIGFGSLRNLTFVDLSNN-----RFTDQIPADFATAPVLQYLN 441
Query 414 LTKN 417
L+ N
Sbjct 442 LSTN 445
Score = 38.1 bits (87), Expect = 0.44, Method: Compositional matrix adjust.
Identities = 78/325 (24%), Positives = 129/325 (40%), Gaps = 25/325 (8%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L+ LE LN + G + GL LK++ L+ + + ++ L +
Sbjct 146 LRFLEELNFGGSYFEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLT----ELQHME 201
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
+ N + F+ L +L+ D+ + L QE L N+ ++L N +
Sbjct 202 IGYNHFNGNIPSEFALLSNLKYFDVSNASLSGSLP-QELGNLSNLETLFLFQNGFTGEIP 260
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
S++ + SL+ L L S PS F L+NLT L L +NN++ + + L +L
Sbjct 261 ESYSNLKSLKLLDFSSNQLSG--SIPSGFSTLKNLTWLSLISNNLSGEVPEGIGELPELT 318
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIID 592
L L +NN + H L L +++ +N F IP + K+I
Sbjct 319 TLFLWNNNFTGVLPHK--------LGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLIL 370
Query 593 LGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFN------P 646
LP S+ + SL Q N + FG + RNLT +D+ N P
Sbjct 371 FSNMFEGELPKSLTRCE-SLWRFRSQNNRLNGTIPIGFG-SLRNLTFVDLSNNRFTDQIP 428
Query 647 FDCTCESIAWFVNW-INETHTNIPE 670
D + ++N N H +PE
Sbjct 429 ADFATAPVLQYLNLSTNFFHRKLPE 453
>5jfk_A A Leucine-rich repeat receptor-like protein kinase TDR
Length=613
Score = 50.1 bits (118), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 94/390 (24%), Positives = 157/390 (40%), Gaps = 38/390 (10%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL-KRS 332
T L +++ YN+ N FA L L+YF + ++ L L N+ L L +
Sbjct 196 TELQHMEIGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLPQELGNLSNLETLFLFQNG 255
Query 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
FT + +P+ S+ LK L+ L+ N + G + F+ L NL +LSL ++
Sbjct 256 FTGE------IPE----SYSNLKSLKLLDFSSNQLSGSIPSGFSTLKNLTWLSLISN--- 302
Query 393 LRTLTNETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
L+ E + P L L L N + + G LE +D+ N +
Sbjct 303 --NLSGEVPEGIGELPELTTLFLWNNNFTGVLPHKLGSNGKLETMDVSNNSFTGTIPSSL 360
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
G ++++ L N + S SL R + L + P F LRNLT +
Sbjct 361 CHG-NKLYKLILFSNMFEGELPKSLTRCESLWRFRSQNNRLNG--TIPIGFGSLRNLTFV 417
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLAR-----LWKHANPG----------GPIY 556
DLSNN + L+ L+L N R +WK N G I
Sbjct 418 DLSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPENIWKAPNLQIFSASFSNLIGEIP 477
Query 557 FLKGLSHLHILNLESNGFD-EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSL 615
G + + L+ N + IP ++ +L ++L N+LN + + S+ +
Sbjct 478 NYVGCKSFYRIELQGNSLNGTIPWDI-GHCEKLLCLNLSQNHLNGIIPWEISTLPSIADV 536
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
+L NL+T FG + + +T ++ +N
Sbjct 537 DLSHNLLTGTIPSDFGSS-KTITTFNVSYN 565
Score = 41.2 bits (95), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 141/364 (39%), Gaps = 38/364 (10%)
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
++LT+LD+ N+ P KL LKV N N L + L EL+ +
Sbjct 100 TKLTTLDISRNSFDSSFPPGISKLKFLKVFNAFSNNFEGLLPSDVSRLRFLEELNFGGSY 159
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+ + + L + L+ N L L LQ + + N E +
Sbjct 160 FEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLTELQHMEIGYNHFNGNIPSEFALL 219
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNL 253
+N LK ++S+ + P + L LFL Q G T ++ +N S++ L
Sbjct 220 SN--LKYFDVSNCSLSGSLPQELGNLSNLETLFL--FQNG--FTGEIPESYSNLKSLKLL 273
Query 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
S++QLS + + F LK NLT L L NNL+ + LP+L FL NN +
Sbjct 274 DFSSNQLSGSIPSGFSTLK--NLTWLSLISNNLSGEVPEGIGELPELTTLFLWNNNFTGV 331
Query 314 FSHSLHGLFNVRYLNLK-RSFTKQSISL------------------ASLPKIDDFSFQWL 354
H L + +++ SFT S LPK S
Sbjct 332 LPHKLGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLILFSNMFEGELPK----SLTRC 387
Query 355 KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILN 413
+ L ++N + G F L NL ++ LSN+ T++ A +P L LN
Sbjct 388 ESLWRFRSQNNRLNGTIPIGFGSLRNLTFVDLSNN-----RFTDQIPADFATAPVLQYLN 442
Query 414 LTKN 417
L+ N
Sbjct 443 LSTN 446
Score = 37.7 bits (86), Expect = 0.67, Method: Compositional matrix adjust.
Identities = 79/336 (24%), Positives = 131/336 (39%), Gaps = 47/336 (14%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L+ LE LN + G + GL LK++ L+ + + ++ L +
Sbjct 147 LRFLEELNFGGSYFEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLT----ELQHME 202
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
+ N + F+ L +L+ D+ + L QE L N+ ++L N +
Sbjct 203 IGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLP-QELGNLSNLETLFLFQNGFTGEIP 261
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
S++ + SL+ L L S PS F L+NLT L L +NN++ + + L +L
Sbjct 262 ESYSNLKSLKLLDFSSNQLSG--SIPSGFSTLKNLTWLSLISNNLSGEVPEGIGELPELT 319
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF-DEIPVE-----------V 581
L L +NN + H L L +++ +N F IP +
Sbjct 320 TLFLWNNNFTGVLPHK--------LGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLIL 371
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
F ++FE LP S+ + SL Q N + FG + RNLT +D
Sbjct 372 FSNMFE-----------GELPKSLTRCE-SLWRFRSQNNRLNGTIPIGFG-SLRNLTFVD 418
Query 642 MRFN------PFDCTCESIAWFVNW-INETHTNIPE 670
+ N P D + ++N N H +PE
Sbjct 419 LSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPE 454
>5jfi_C B Leucine-rich repeat receptor-like protein kinase TDR
Length=613
Score = 50.1 bits (118), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 94/390 (24%), Positives = 157/390 (40%), Gaps = 38/390 (10%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL-KRS 332
T L +++ YN+ N FA L L+YF + ++ L L N+ L L +
Sbjct 196 TELQHMEIGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLPQELGNLSNLETLFLFQNG 255
Query 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
FT + +P+ S+ LK L+ L+ N + G + F+ L NL +LSL ++
Sbjct 256 FTGE------IPE----SYSNLKSLKLLDFSSNQLSGSIPSGFSTLKNLTWLSLISN--- 302
Query 393 LRTLTNETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
L+ E + P L L L N + + G LE +D+ N +
Sbjct 303 --NLSGEVPEGIGELPELTTLFLWNNNFTGVLPHKLGSNGKLETMDVSNNSFTGTIPSSL 360
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
G ++++ L N + S SL R + L + P F LRNLT +
Sbjct 361 CHG-NKLYKLILFSNMFEGELPKSLTRCESLWRFRSQNNRLNG--TIPIGFGSLRNLTFV 417
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLAR-----LWKHANPG----------GPIY 556
DLSNN + L+ L+L N R +WK N G I
Sbjct 418 DLSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPENIWKAPNLQIFSASFSNLIGEIP 477
Query 557 FLKGLSHLHILNLESNGFD-EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSL 615
G + + L+ N + IP ++ +L ++L N+LN + + S+ +
Sbjct 478 NYVGCKSFYRIELQGNSLNGTIPWDI-GHCEKLLCLNLSQNHLNGIIPWEISTLPSIADV 536
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
+L NL+T FG + + +T ++ +N
Sbjct 537 DLSHNLLTGTIPSDFGSS-KTITTFNVSYN 565
Score = 41.2 bits (95), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 141/364 (39%), Gaps = 38/364 (10%)
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
++LT+LD+ N+ P KL LKV N N L + L EL+ +
Sbjct 100 TKLTTLDISRNSFDSSFPPGISKLKFLKVFNAFSNNFEGLLPSDVSRLRFLEELNFGGSY 159
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+ + + L + L+ N L L LQ + + N E +
Sbjct 160 FEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLTELQHMEIGYNHFNGNIPSEFALL 219
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNL 253
+N LK ++S+ + P + L LFL Q G T ++ +N S++ L
Sbjct 220 SN--LKYFDVSNCSLSGSLPQELGNLSNLETLFL--FQNG--FTGEIPESYSNLKSLKLL 273
Query 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
S++QLS + + F LK NLT L L NNL+ + LP+L FL NN +
Sbjct 274 DFSSNQLSGSIPSGFSTLK--NLTWLSLISNNLSGEVPEGIGELPELTTLFLWNNNFTGV 331
Query 314 FSHSLHGLFNVRYLNLK-RSFTKQSISL------------------ASLPKIDDFSFQWL 354
H L + +++ SFT S LPK S
Sbjct 332 LPHKLGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLILFSNMFEGELPK----SLTRC 387
Query 355 KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILN 413
+ L ++N + G F L NL ++ LSN+ T++ A +P L LN
Sbjct 388 ESLWRFRSQNNRLNGTIPIGFGSLRNLTFVDLSNN-----RFTDQIPADFATAPVLQYLN 442
Query 414 LTKN 417
L+ N
Sbjct 443 LSTN 446
Score = 37.7 bits (86), Expect = 0.67, Method: Compositional matrix adjust.
Identities = 79/336 (24%), Positives = 131/336 (39%), Gaps = 47/336 (14%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L+ LE LN + G + GL LK++ L+ + + ++ L +
Sbjct 147 LRFLEELNFGGSYFEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLT----ELQHME 202
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
+ N + F+ L +L+ D+ + L QE L N+ ++L N +
Sbjct 203 IGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLP-QELGNLSNLETLFLFQNGFTGEIP 261
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
S++ + SL+ L L S PS F L+NLT L L +NN++ + + L +L
Sbjct 262 ESYSNLKSLKLLDFSSNQLSG--SIPSGFSTLKNLTWLSLISNNLSGEVPEGIGELPELT 319
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF-DEIPVE-----------V 581
L L +NN + H L L +++ +N F IP +
Sbjct 320 TLFLWNNNFTGVLPHK--------LGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLIL 371
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
F ++FE LP S+ + SL Q N + FG + RNLT +D
Sbjct 372 FSNMFE-----------GELPKSLTRCE-SLWRFRSQNNRLNGTIPIGFG-SLRNLTFVD 418
Query 642 MRFN------PFDCTCESIAWFVNW-INETHTNIPE 670
+ N P D + ++N N H +PE
Sbjct 419 LSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPE 454
>5jfi_A A Leucine-rich repeat receptor-like protein kinase TDR
Length=613
Score = 50.1 bits (118), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 94/390 (24%), Positives = 157/390 (40%), Gaps = 38/390 (10%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL-KRS 332
T L +++ YN+ N FA L L+YF + ++ L L N+ L L +
Sbjct 196 TELQHMEIGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLPQELGNLSNLETLFLFQNG 255
Query 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
FT + +P+ S+ LK L+ L+ N + G + F+ L NL +LSL ++
Sbjct 256 FTGE------IPE----SYSNLKSLKLLDFSSNQLSGSIPSGFSTLKNLTWLSLISN--- 302
Query 393 LRTLTNETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
L+ E + P L L L N + + G LE +D+ N +
Sbjct 303 --NLSGEVPEGIGELPELTTLFLWNNNFTGVLPHKLGSNGKLETMDVSNNSFTGTIPSSL 360
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
G ++++ L N + S SL R + L + P F LRNLT +
Sbjct 361 CHG-NKLYKLILFSNMFEGELPKSLTRCESLWRFRSQNNRLNG--TIPIGFGSLRNLTFV 417
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLAR-----LWKHANPG----------GPIY 556
DLSNN + L+ L+L N R +WK N G I
Sbjct 418 DLSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPENIWKAPNLQIFSASFSNLIGEIP 477
Query 557 FLKGLSHLHILNLESNGFD-EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSL 615
G + + L+ N + IP ++ +L ++L N+LN + + S+ +
Sbjct 478 NYVGCKSFYRIELQGNSLNGTIPWDI-GHCEKLLCLNLSQNHLNGIIPWEISTLPSIADV 536
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
+L NL+T FG + + +T ++ +N
Sbjct 537 DLSHNLLTGTIPSDFGSS-KTITTFNVSYN 565
Score = 41.2 bits (95), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 141/364 (39%), Gaps = 38/364 (10%)
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
++LT+LD+ N+ P KL LKV N N L + L EL+ +
Sbjct 100 TKLTTLDISRNSFDSSFPPGISKLKFLKVFNAFSNNFEGLLPSDVSRLRFLEELNFGGSY 159
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+ + + L + L+ N L L LQ + + N E +
Sbjct 160 FEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLTELQHMEIGYNHFNGNIPSEFALL 219
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNL 253
+N LK ++S+ + P + L LFL Q G T ++ +N S++ L
Sbjct 220 SN--LKYFDVSNCSLSGSLPQELGNLSNLETLFL--FQNG--FTGEIPESYSNLKSLKLL 273
Query 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
S++QLS + + F LK NLT L L NNL+ + LP+L FL NN +
Sbjct 274 DFSSNQLSGSIPSGFSTLK--NLTWLSLISNNLSGEVPEGIGELPELTTLFLWNNNFTGV 331
Query 314 FSHSLHGLFNVRYLNLK-RSFTKQSISL------------------ASLPKIDDFSFQWL 354
H L + +++ SFT S LPK S
Sbjct 332 LPHKLGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLILFSNMFEGELPK----SLTRC 387
Query 355 KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILN 413
+ L ++N + G F L NL ++ LSN+ T++ A +P L LN
Sbjct 388 ESLWRFRSQNNRLNGTIPIGFGSLRNLTFVDLSNN-----RFTDQIPADFATAPVLQYLN 442
Query 414 LTKN 417
L+ N
Sbjct 443 LSTN 446
Score = 37.7 bits (86), Expect = 0.67, Method: Compositional matrix adjust.
Identities = 79/336 (24%), Positives = 131/336 (39%), Gaps = 47/336 (14%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L+ LE LN + G + GL LK++ L+ + + ++ L +
Sbjct 147 LRFLEELNFGGSYFEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLT----ELQHME 202
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
+ N + F+ L +L+ D+ + L QE L N+ ++L N +
Sbjct 203 IGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLP-QELGNLSNLETLFLFQNGFTGEIP 261
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
S++ + SL+ L L S PS F L+NLT L L +NN++ + + L +L
Sbjct 262 ESYSNLKSLKLLDFSSNQLSG--SIPSGFSTLKNLTWLSLISNNLSGEVPEGIGELPELT 319
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF-DEIPVE-----------V 581
L L +NN + H L L +++ +N F IP +
Sbjct 320 TLFLWNNNFTGVLPHK--------LGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLIL 371
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
F ++FE LP S+ + SL Q N + FG + RNLT +D
Sbjct 372 FSNMFE-----------GELPKSLTRCE-SLWRFRSQNNRLNGTIPIGFG-SLRNLTFVD 418
Query 642 MRFN------PFDCTCESIAWFVNW-INETHTNIPE 670
+ N P D + ++N N H +PE
Sbjct 419 LSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPE 454
>5jfk_B B Leucine-rich repeat receptor-like protein kinase TDR
Length=613
Score = 50.1 bits (118), Expect = 9e-05, Method: Compositional matrix adjust.
Identities = 94/390 (24%), Positives = 157/390 (40%), Gaps = 38/390 (10%)
Query 274 TNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL-KRS 332
T L +++ YN+ N FA L L+YF + ++ L L N+ L L +
Sbjct 196 TELQHMEIGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLPQELGNLSNLETLFLFQNG 255
Query 333 FTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS 392
FT + +P+ S+ LK L+ L+ N + G + F+ L NL +LSL ++
Sbjct 256 FTGE------IPE----SYSNLKSLKLLDFSSNQLSGSIPSGFSTLKNLTWLSLISN--- 302
Query 393 LRTLTNETFVSLAHSP-LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQE 451
L+ E + P L L L N + + G LE +D+ N +
Sbjct 303 --NLSGEVPEGIGELPELTTLFLWNNNFTGVLPHKLGSNGKLETMDVSNNSFTGTIPSSL 360
Query 452 WRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTIL 511
G ++++ L N + S SL R + L + P F LRNLT +
Sbjct 361 CHG-NKLYKLILFSNMFEGELPKSLTRCESLWRFRSQNNRLNG--TIPIGFGSLRNLTFV 417
Query 512 DLSNNNIANINDDMLEGLEKLEILDLQHNNLAR-----LWKHANPG----------GPIY 556
DLSNN + L+ L+L N R +WK N G I
Sbjct 418 DLSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPENIWKAPNLQIFSASFSNLIGEIP 477
Query 557 FLKGLSHLHILNLESNGFD-EIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSL 615
G + + L+ N + IP ++ +L ++L N+LN + + S+ +
Sbjct 478 NYVGCKSFYRIELQGNSLNGTIPWDI-GHCEKLLCLNLSQNHLNGIIPWEISTLPSIADV 536
Query 616 NLQKNLITSVEKKVFGPAFRNLTELDMRFN 645
+L NL+T FG + + +T ++ +N
Sbjct 537 DLSHNLLTGTIPSDFGSS-KTITTFNVSYN 565
Score = 41.2 bits (95), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 91/364 (25%), Positives = 141/364 (39%), Gaps = 38/364 (10%)
Query 75 SQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNS 134
++LT+LD+ N+ P KL LKV N N L + L EL+ +
Sbjct 100 TKLTTLDISRNSFDSSFPPGISKLKFLKVFNAFSNNFEGLLPSDVSRLRFLEELNFGGSY 159
Query 135 IQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+ + + L + L+ N L L LQ + + N E +
Sbjct 160 FEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLTELQHMEIGYNHFNGNIPSEFALL 219
Query 195 ANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELAN-TSIRNL 253
+N LK ++S+ + P + L LFL Q G T ++ +N S++ L
Sbjct 220 SN--LKYFDVSNCSLSGSLPQELGNLSNLETLFL--FQNG--FTGEIPESYSNLKSLKLL 273
Query 254 SLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHL 313
S++QLS + + F LK NLT L L NNL+ + LP+L FL NN +
Sbjct 274 DFSSNQLSGSIPSGFSTLK--NLTWLSLISNNLSGEVPEGIGELPELTTLFLWNNNFTGV 331
Query 314 FSHSLHGLFNVRYLNLK-RSFTKQSISL------------------ASLPKIDDFSFQWL 354
H L + +++ SFT S LPK S
Sbjct 332 LPHKLGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLILFSNMFEGELPK----SLTRC 387
Query 355 KCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSP-LHILN 413
+ L ++N + G F L NL ++ LSN+ T++ A +P L LN
Sbjct 388 ESLWRFRSQNNRLNGTIPIGFGSLRNLTFVDLSNN-----RFTDQIPADFATAPVLQYLN 442
Query 414 LTKN 417
L+ N
Sbjct 443 LSTN 446
Score = 37.7 bits (86), Expect = 0.67, Method: Compositional matrix adjust.
Identities = 79/336 (24%), Positives = 131/336 (39%), Gaps = 47/336 (14%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L+ LE LN + G + GL LK++ L+ + + ++ L +
Sbjct 147 LRFLEELNFGGSYFEGEIPAAYGGLQRLKFIHLAGNVLGGKLPPRLGLLT----ELQHME 202
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
+ N + F+ L +L+ D+ + L QE L N+ ++L N +
Sbjct 203 IGYNHFNGNIPSEFALLSNLKYFDVSNCSLSGSLP-QELGNLSNLETLFLFQNGFTGEIP 261
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
S++ + SL+ L L S PS F L+NLT L L +NN++ + + L +L
Sbjct 262 ESYSNLKSLKLLDFSSNQLSG--SIPSGFSTLKNLTWLSLISNNLSGEVPEGIGELPELT 319
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGF-DEIPVE-----------V 581
L L +NN + H L L +++ +N F IP +
Sbjct 320 TLFLWNNNFTGVLPHK--------LGSNGKLETMDVSNNSFTGTIPSSLCHGNKLYKLIL 371
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
F ++FE LP S+ + SL Q N + FG + RNLT +D
Sbjct 372 FSNMFE-----------GELPKSLTRCE-SLWRFRSQNNRLNGTIPIGFG-SLRNLTFVD 418
Query 642 MRFN------PFDCTCESIAWFVNW-INETHTNIPE 670
+ N P D + ++N N H +PE
Sbjct 419 LSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPE 454
>2wfh_B B SLIT HOMOLOG 2 PROTEIN C-PRODUCT
Length=193
Score = 48.1 bits (113), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 40/134 (30%), Positives = 58/134 (43%), Gaps = 1/134 (1%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
T+CT V CS+ L +P +P ++T L L NQ +P + Y LT +D+ N
Sbjct 6 TECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVP-KELSNYKHLTLIDLSNN 64
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
IS L + + L L L +N L + +TF +L L L N I + F
Sbjct 65 RISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFND 124
Query 146 QKNLITLDLSHNGL 159
L L + N L
Sbjct 125 LSALSHLAIGANPL 138
Score = 42.0 bits (97), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 8/100 (8%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
P ++LT++DLSNN I+ +++ + +L L L +N L + P
Sbjct 47 PKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCI--------PPRTF 98
Query 559 KGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
GL L +L+L N +P F DL L + +G N L
Sbjct 99 DGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 138
Score = 38.5 bits (88), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 26/95 (27%), Positives = 49/95 (52%), Gaps = 13/95 (14%)
Query 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL--- 329
+ +LT++DLS N ++ + N SF+ + QL L YN ++ + + GL ++R L+L
Sbjct 53 YKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGN 112
Query 330 ------KRSFTKQS----ISLASLPKIDDFSFQWL 354
+ +F S +++ + P D + QWL
Sbjct 113 DISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWL 147
>2wfh_A A SLIT HOMOLOG 2 PROTEIN C-PRODUCT
Length=193
Score = 48.1 bits (113), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 40/134 (30%), Positives = 58/134 (43%), Gaps = 1/134 (1%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
T+CT V CS+ L +P +P ++T L L NQ +P + Y LT +D+ N
Sbjct 6 TECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVP-KELSNYKHLTLIDLSNN 64
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
IS L + + L L L +N L + +TF +L L L N I + F
Sbjct 65 RISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFND 124
Query 146 QKNLITLDLSHNGL 159
L L + N L
Sbjct 125 LSALSHLAIGANPL 138
Score = 42.0 bits (97), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 8/100 (8%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
P ++LT++DLSNN I+ +++ + +L L L +N L + P
Sbjct 47 PKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCI--------PPRTF 98
Query 559 KGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
GL L +L+L N +P F DL L + +G N L
Sbjct 99 DGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPL 138
Score = 38.5 bits (88), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 26/95 (27%), Positives = 49/95 (52%), Gaps = 13/95 (14%)
Query 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNL--- 329
+ +LT++DLS N ++ + N SF+ + QL L YN ++ + + GL ++R L+L
Sbjct 53 YKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLHGN 112
Query 330 ------KRSFTKQS----ISLASLPKIDDFSFQWL 354
+ +F S +++ + P D + QWL
Sbjct 113 DISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWL 147
>8ds3_F F Volume-regulated anion channel subunit LRRC8C
Length=813
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 589 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 647
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + T+L L N ++ + ++ F+ K + LDLS+N + V
Sbjct 648 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 704
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LFL+
Sbjct 705 LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LFLS 755
Query 230 NVQLGPSLTEKLCLELAN 247
+ + + E L EL +
Sbjct 756 YLDIKGNHFEVLPPELGD 773
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 81/294 (28%), Positives = 142/294 (48%), Gaps = 23/294 (8%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--LRTLTNETFVSLAHSPLHILNL 414
L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+ L L IL++
Sbjct 493 LKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHDISKNVTLESLRDL--KSLKILSI 549
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
N +SKI HL+ + + N+ + + + + N+ E+ L + ++
Sbjct 550 KSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELELVHCDLERIPHA 607
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I + ++ L LE
Sbjct 608 VFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIPEH-IKKLTSLER 664
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L HN + L H I + L+L N IP E+ L L+ +
Sbjct 665 LFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI-GVLQSLQYFSIT 714
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
N + +LP ++ + LK+L + KN ++ + K+ F L+ LD++ N F+
Sbjct 715 CNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDIKGNHFE 765
>8f77_F F Volume-regulated anion channel subunit LRRC8C
Length=813
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 589 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 647
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + T+L L N ++ + ++ F+ K + LDLS+N + V
Sbjct 648 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 704
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LFL+
Sbjct 705 LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LFLS 755
Query 230 NVQLGPSLTEKLCLELAN 247
+ + + E L EL +
Sbjct 756 YLDIKGNHFEVLPPELGD 773
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 81/294 (28%), Positives = 142/294 (48%), Gaps = 23/294 (8%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--LRTLTNETFVSLAHSPLHILNL 414
L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+ L L IL++
Sbjct 493 LKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHDISKNVTLESLRDL--KSLKILSI 549
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
N +SKI HL+ + + N+ + + + + N+ E+ L + ++
Sbjct 550 KSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELELVHCDLERIPHA 607
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I + ++ L LE
Sbjct 608 VFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIPEH-IKKLTSLER 664
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L HN + L H I + L+L N IP E+ L L+ +
Sbjct 665 LFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI-GVLQSLQYFSIT 714
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
N + +LP ++ + LK+L + KN ++ + K+ F L+ LD++ N F+
Sbjct 715 CNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDIKGNHFE 765
>8f79_F F Volume-regulated anion channel subunit LRRC8C
Length=813
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 589 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 647
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + T+L L N ++ + ++ F+ K + LDLS+N + V
Sbjct 648 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 704
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LFL+
Sbjct 705 LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LFLS 755
Query 230 NVQLGPSLTEKLCLELAN 247
+ + + E L EL +
Sbjct 756 YLDIKGNHFEVLPPELGD 773
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 81/294 (28%), Positives = 142/294 (48%), Gaps = 23/294 (8%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--LRTLTNETFVSLAHSPLHILNL 414
L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+ L L IL++
Sbjct 493 LKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHDISKNVTLESLRDL--KSLKILSI 549
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
N +SKI HL+ + + N+ + + + + N+ E+ L + ++
Sbjct 550 KSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELELVHCDLERIPHA 607
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I + ++ L LE
Sbjct 608 VFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIPEH-IKKLTSLER 664
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L HN + L H I + L+L N IP E+ L L+ +
Sbjct 665 LFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI-GVLQSLQYFSIT 714
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
N + +LP ++ + LK+L + KN ++ + K+ F L+ LD++ N F+
Sbjct 715 CNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDIKGNHFE 765
>8dre_F F Volume-regulated anion channel subunit LRRC8C
Length=813
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 59/198 (30%), Positives = 98/198 (49%), Gaps = 14/198 (7%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 589 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 647
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
++ + + T+L L N ++ + ++ F+ K + LDLS+N + V
Sbjct 648 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 704
Query 170 LENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLN 229
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LFL+
Sbjct 705 LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LFLS 755
Query 230 NVQLGPSLTEKLCLELAN 247
+ + + E L EL +
Sbjct 756 YLDIKGNHFEVLPPELGD 773
Score = 50.1 bits (118), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 81/294 (28%), Positives = 142/294 (48%), Gaps = 23/294 (8%)
Query 357 LEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--LRTLTNETFVSLAHSPLHILNL 414
L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+ L L IL++
Sbjct 493 LKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHDISKNVTLESLRDL--KSLKILSI 549
Query 415 TKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRN 474
N +SKI HL+ + + N+ + + + + N+ E+ L + ++
Sbjct 550 KSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELELVHCDLERIPHA 607
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I + ++ L LE
Sbjct 608 VFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIPEH-IKKLTSLER 664
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
L HN + L H I + L+L N IP E+ L L+ +
Sbjct 665 LFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI-GVLQSLQYFSIT 714
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFD 648
N + +LP ++ + LK+L + KN ++ + K+ F L+ LD++ N F+
Sbjct 715 CNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDIKGNHFE 765
>3jb9_HA j U2 small nuclear ribonucleoprotein A'
Length=239
Score = 48.5 bits (114), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/84 (33%), Positives = 45/84 (54%), Gaps = 3/84 (4%)
Query 55 VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
++ T N +R L NF R +L +L G N I+ + P++ + LP LK L+L N L ++
Sbjct 45 AIDFTDNDIRYL--GNFPRMKRLQTLLCGNNRITAIAPDIGKVLPNLKTLSLAQNHLQEI 102
Query 115 SD-KTFAFCTNLTELHLMSNSIQK 137
+D A C LT L + N + +
Sbjct 103 ADLDPLASCPQLTNLSCIDNPVAQ 126
>1o6v_A A INTERNALIN A
Length=466
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 145/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L G N ++ L+P L L+ L++ N+
Sbjct 134 TNLNRLELSSNTISDISA--LSGLTSLQQLSFG-NQVTDLKP--LANLTTLERLDISSNK 188
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 189 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 242
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 243 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 286
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 287 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 325
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 326 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 381
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 382 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 424
Score = 42.7 bits (99), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 67/238 (28%), Positives = 99/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ LS N T L+ L N T L L+
Sbjct 133 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFGNQVTDLKPLANLTT-------LERLD 183
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 184 ISSNKVSDIS--VLAKLTNLESLIATNNQI-SDIT------------------------- 215
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 216 -PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKLT 268
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 269 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 316
>8h64_G G Internalin A
Length=462
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 145/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L G N ++ L+P L L+ L++ N+
Sbjct 130 TNLNRLELSSNTISDISA--LSGLTSLQQLSFG-NQVTDLKP--LANLTTLERLDISSNK 184
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 185 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 238
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 239 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 282
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 283 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 321
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 322 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 377
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 378 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 420
Score = 42.4 bits (98), Expect = 0.021, Method: Compositional matrix adjust.
Identities = 67/238 (28%), Positives = 99/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ LS N T L+ L N T L L+
Sbjct 129 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFGNQVTDLKPLANLTT-------LERLD 179
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 180 ISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------- 211
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 212 -PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKLT 264
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 265 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 312
>8h64_C C Internalin A
Length=462
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 145/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L G N ++ L+P L L+ L++ N+
Sbjct 130 TNLNRLELSSNTISDISA--LSGLTSLQQLSFG-NQVTDLKP--LANLTTLERLDISSNK 184
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 185 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 238
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 239 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 282
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 283 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 321
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 322 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 377
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 378 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 420
Score = 42.7 bits (99), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 67/238 (28%), Positives = 99/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ LS N T L+ L N T L L+
Sbjct 129 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFGNQVTDLKPLANLTT-------LERLD 179
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 180 ISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------- 211
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 212 -PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKLT 264
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 265 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 312
>1o6s_A A INTERNALIN A
Length=466
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 145/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L G N ++ L+P L L+ L++ N+
Sbjct 134 TNLNRLELSSNTISDISA--LSGLTSLQQLSFG-NQVTDLKP--LANLTTLERLDISSNK 188
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 189 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 242
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 243 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 286
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 287 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 325
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 326 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 381
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 382 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 424
Score = 42.7 bits (99), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 67/238 (28%), Positives = 99/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ LS N T L+ L N T L L+
Sbjct 133 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFGNQVTDLKPLANLTT-------LERLD 183
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 184 ISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------- 215
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 216 -PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKLT 268
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 269 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 316
>1o6v_B B INTERNALIN A
Length=466
Score = 49.3 bits (116), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 145/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L G N ++ L+P L L+ L++ N+
Sbjct 134 TNLNRLELSSNTISDISA--LSGLTSLQQLSFG-NQVTDLKP--LANLTTLERLDISSNK 188
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 189 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 242
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 243 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 286
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 287 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 325
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 326 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 381
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 382 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 424
Score = 42.7 bits (99), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 67/238 (28%), Positives = 99/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ LS N T L+ L N T L L+
Sbjct 133 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFGNQVTDLKPLANLTT-------LERLD 183
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 184 ISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------- 215
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 216 -PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKLT 268
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 269 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 316
>8h62_A A Internalin A
Length=462
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 145/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L G N ++ L+P L L+ L++ N+
Sbjct 130 TNLNRLELSSNTISDISA--LSGLTSLQQLSFG-NQVTDLKP--LANLTTLERLDISSNK 184
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 185 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 238
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 239 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 282
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 283 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 321
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 322 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 377
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 378 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 420
Score = 42.7 bits (99), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 67/238 (28%), Positives = 99/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ LS N T L+ L N T L L+
Sbjct 129 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFGNQVTDLKPLANLTT-------LERLD 179
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 180 ISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------- 211
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 212 -PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKLT 264
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 265 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 312
>8h63_A A Internalin A
Length=462
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 145/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L G N ++ L+P L L+ L++ N+
Sbjct 130 TNLNRLELSSNTISDISA--LSGLTSLQQLSFG-NQVTDLKP--LANLTTLERLDISSNK 184
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 185 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 238
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 239 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 282
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 283 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 321
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 322 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 377
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 378 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 420
Score = 42.7 bits (99), Expect = 0.017, Method: Compositional matrix adjust.
Identities = 67/238 (28%), Positives = 99/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ LS N T L+ L N T L L+
Sbjct 129 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFGNQVTDLKPLANLTT-------LERLD 179
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 180 ISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------- 211
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 212 -PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKLT 264
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 265 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 312
>1o6t_A A INTERNALIN A
Length=466
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 145/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L G N ++ L+P L L+ L++ N+
Sbjct 134 TNLNRLELSSNTISDISA--LSGLTSLQQLSFG-NQVTDLKP--LANLTTLERLDISSNK 188
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 189 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 242
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 243 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 286
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 287 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 325
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 326 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 381
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 382 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 424
Score = 42.7 bits (99), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 67/238 (28%), Positives = 99/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ LS N T L+ L N T L L+
Sbjct 133 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFGNQVTDLKPLANLTT-------LERLD 183
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 184 ISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------- 215
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + L NLT LDL+NN I+N+ L GL KL
Sbjct 216 -PLGILTNLDELSLNGNQLKDIGT----LASLTNLTDLDLANNQISNL--APLSGLTKLT 268
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 269 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 316
>8ben_A A Volume-regulated anion channel subunit LRRC8C
Length=412
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 87/306 (28%), Positives = 146/306 (48%), Gaps = 22/306 (7%)
Query 345 KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS 403
KI + +LK L+ L+++ +D+ + M+ GL NL+ L L S S N T S
Sbjct 88 KIHSAALSFLKENLKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSL-SXXXXKNVTLES 145
Query 404 LAH-SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY 462
L L IL++ N +SKI HL+ + + N+ + + + + N+ E+
Sbjct 146 LRDLKSLKILSIKSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELE 203
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
L + ++ F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I
Sbjct 204 LVHCDLERIPHAVFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYIP 261
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF 582
+ ++ L LE L HN + L H I + L+L N IP E+
Sbjct 262 EH-IKKLTSLERLFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI- 310
Query 583 KDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDM 642
L L+ + N + +LP ++ + LK+L + KN ++ + K+ F L+ LD+
Sbjct 311 GVLQSLQYFSITCNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDI 367
Query 643 RFNPFD 648
+ N F+
Sbjct 368 KGNHFE 373
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 59/200 (30%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 197 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 255
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + T+L L N ++ + ++ F+ K + LDLS+N + ++G
Sbjct 256 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 312
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF 227
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LF
Sbjct 313 --LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LF 361
Query 228 LNNVQLGPSLTEKLCLELAN 247
L+ + + + E L EL +
Sbjct 362 LSYLDIKGNHFEVLPPELGD 381
>4hq1_A A Probable receptor protein kinase TMK1
Length=475
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 38/123 (31%), Positives = 63/123 (51%), Gaps = 13/123 (11%)
Query 526 LEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDL 585
L L +LE L+LQ NN++ GP+ L GL+ L +L L +N FD IP +VF+ L
Sbjct 84 LRNLSELERLELQWNNIS---------GPVPSLSGLASLQVLMLSNNNFDSIPSDVFQGL 134
Query 586 FELKIIDLGLNNLNT--LPASVFNNQVSLKSLNLQKNLITSVEKKVFGP-AFRNLTELDM 642
L+ +++ N + +P S+ N +L++ + ++ GP F L+ L +
Sbjct 135 TSLQSVEIDNNPFKSWEIPESL-RNASALQNFSANSANVSGSLPGFLGPDEFPGLSILHL 193
Query 643 RFN 645
FN
Sbjct 194 AFN 196
Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 50/149 (34%), Positives = 71/149 (48%), Gaps = 13/149 (9%)
Query 477 ALVPSLQRLM-LRRVALK-NVDSSPSP-FQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
L P L+ L L R+ L+ N S P P L +L +L LSNNN +I D+ +GL L+
Sbjct 79 TLSPDLRNLSELERLELQWNNISGPVPSLSGLASLQVLMLSNNNFDSIPSDVFQGLTSLQ 138
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLES-NGFDEIPVEVFKDLFE-LKII 591
+++ NN + W+ L+ S L + S N +P + D F L I+
Sbjct 139 SVEID-NNPFKSWEIPE------SLRNASALQNFSANSANVSGSLPGFLGPDEFPGLSIL 191
Query 592 DLGLNNL-NTLPASVFNNQVSLKSLNLQK 619
L NNL LP S+ +QV LN QK
Sbjct 192 HLAFNNLEGELPMSLAGSQVQSLWLNGQK 220
>8ben_B B Volume-regulated anion channel subunit LRRC8C
Length=412
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 88/306 (29%), Positives = 148/306 (48%), Gaps = 22/306 (7%)
Query 345 KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVS 403
KI + +LK L+ L+++ +D+ + M+ GL NL+ L L S S N T S
Sbjct 88 KIHSAALSFLKENLKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSL-SXXXXKNVTLES 145
Query 404 LAH-SPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY 462
L L IL++ N +SKI HL+ + + N+ + + + + N+ E+
Sbjct 146 LRDLKSLKILSIKSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTELE 203
Query 463 LSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANIN 522
L + ++ F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I
Sbjct 204 LVHCDLERIPHAVFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYI- 260
Query 523 DDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVF 582
+ ++ L LE L HN + L H FL + + L+L N IP E+
Sbjct 261 PEHIKKLTSLERLFFSHNKVEVLPSH-------LFL--CNKIRYLDLSYNDIRFIPPEI- 310
Query 583 KDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDM 642
L L+ + N + +LP ++ + LK+L + KN ++ + K+ F L+ LD+
Sbjct 311 GVLQSLQYFSITCNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLDI 367
Query 643 RFNPFD 648
+ N F+
Sbjct 368 KGNHFE 373
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 59/200 (30%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 197 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 255
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + T+L L N ++ + ++ F+ K + LDLS+N + ++G
Sbjct 256 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 312
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF 227
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LF
Sbjct 313 --LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LF 361
Query 228 LNNVQLGPSLTEKLCLELAN 247
L+ + + + E L EL +
Sbjct 362 LSYLDIKGNHFEVLPPELGD 381
>8h64_A A Internalin A
Length=462
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 145/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L G N ++ L+P L L+ L++ N+
Sbjct 130 TNLNRLELSSNTISDISA--LSGLTSLQQLSFG-NQVTDLKP--LANLTTLERLDISSNK 184
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 185 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 238
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 239 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 282
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 283 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 321
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 322 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 377
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 378 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 420
Score = 42.4 bits (98), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 68/238 (29%), Positives = 100/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ LS N T L+ L N T L L+
Sbjct 129 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFGNQVTDLKPLANLTT-------LERLD 179
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 180 ISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------- 211
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + S L NLT LDL+NN I+N+ L GL KL
Sbjct 212 -PLGILTNLDELSLNGNQLKDIGTLAS----LTNLTDLDLANNQISNL--APLSGLTKLT 264
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 265 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 312
>8h64_E E Internalin A
Length=462
Score = 48.9 bits (115), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 94/345 (27%), Positives = 145/345 (42%), Gaps = 58/345 (17%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
TN+ L L+ N + + A + + L L G N ++ L+P L L+ L++ N+
Sbjct 130 TNLNRLELSSNTISDISA--LSGLTSLQQLSFG-NQVTDLKP--LANLTTLERLDISSNK 184
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+S +S A TNL L +N I I P NL L L+ N L +GT L
Sbjct 185 VSDIS--VLAKLTNLESLIATNNQISDIT--PLGILTNLDELSLNGNQLK--DIGTLASL 238
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NL +L L+NN+I L + + L +L+L +NQI SP L GL
Sbjct 239 TNLTDLDLANNQISNLAP----LSGLTKLTELKLGANQISNISP--------LAGL---- 282
Query 231 VQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVG 290
T++ NL L+ +QL S + L NLT L L +NN++ +
Sbjct 283 -----------------TALTNLELNENQLEDISPISNLK----NLTYLTLYFNNISDIS 321
Query 291 NDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFS 350
+ L +L+ F N + + SL L N+ +L+ + LA+L +I
Sbjct 322 --PVSSLTKLQRLFFYNNKVSDV--SSLANLTNINWLSAGHNQISDLTPLANLTRITQLG 377
Query 351 FQ---WLKCLEHLNMEDN-DIPGIKSNMFTGLINLKYLSLSNSFT 391
W +N + N IP N+ LI +S S+T
Sbjct 378 LNDQAWTNA--PVNYKANVSIPNTVKNVTGALIAPATISDGGSYT 420
Score = 42.4 bits (98), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 68/238 (29%), Positives = 100/238 (42%), Gaps = 55/238 (23%)
Query 354 LKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILN 413
L L L + N I I + +GL +L+ LS N T L+ L N T L L+
Sbjct 129 LTNLNRLELSSNTISDISA--LSGLTSLQQLSFGNQVTDLKPLANLTT-------LERLD 179
Query 414 LTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTR 473
++ NK+S I + L +LE L N+I ++T
Sbjct 180 ISSNKVSDIS--VLAKLTNLESLIATNNQIS-DIT------------------------- 211
Query 474 NSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLE 533
++ +L L L LK++ + S L NLT LDL+NN I+N+ L GL KL
Sbjct 212 -PLGILTNLDELSLNGNQLKDIGTLAS----LTNLTDLDLANNQISNL--APLSGLTKLT 264
Query 534 ILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKI 590
L L N ++ I L GL+ L L L N ++I P+ K+L L +
Sbjct 265 ELKLGANQISN----------ISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTL 312
>2r9u_A A Variable lymphocyte receptor
Length=174
Score = 46.6 bits (109), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 49/109 (45%), Gaps = 31/109 (28%)
Query 565 HILNLE-----SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQK 619
H++NL+ SN IP VF L +L +DL N+L ++P F+N
Sbjct 55 HLVNLQQLYFNSNKLTAIPTGVFDKLTQLTQLDLNDNHLKSIPRGAFDN----------- 103
Query 620 NLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
++LT + + NP+DC C I + NW+ + HT+I
Sbjct 104 --------------LKSLTHIYLYNNPWDCECRDIMYLRNWVAD-HTSI 137
Score = 44.7 bits (104), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 29/112 (26%), Positives = 52/112 (46%), Gaps = 0/112 (0%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLD 81
A ++C+ + +C +++L VP +PT+ L L +NQ+ +L F L L
Sbjct 4 AGCPSQCSCDQTLVNCQNIRLASVPAGIPTDKQRLWLNNNQITKLEPGVFDHLVNLQQLY 63
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
N ++ + + KL L L+L N L + F +LT ++L +N
Sbjct 64 FNSNKLTAIPTGVFDKLTQLTQLDLNDNHLKSIPRGAFDNLKSLTHIYLYNN 115
Score = 33.9 bits (76), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 14/120 (12%)
Query 112 SQLS-DKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
SQ S D+T C N+ L + I P KQ+ L L++N ++ + G L
Sbjct 8 SQCSCDQTLVNCQNI-RLASVPAGI------PTDKQR----LWLNNNQITKLEPGVFDHL 56
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NLQ+L ++NK+ A+ + D + L +L+L+ N +K G F + L ++L N
Sbjct 57 VNLQQLYFNSNKLTAIPTGVFDKL--TQLTQLDLNDNHLKSIPRGAFDNLKSLTHIYLYN 114
>2r9u_B B Variable lymphocyte receptor
Length=174
Score = 46.6 bits (109), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 49/109 (45%), Gaps = 31/109 (28%)
Query 565 HILNLE-----SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQK 619
H++NL+ SN IP VF L +L +DL N+L ++P F+N
Sbjct 55 HLVNLQQLYFNSNKLTAIPTGVFDKLTQLTQLDLNDNHLKSIPRGAFDN----------- 103
Query 620 NLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
++LT + + NP+DC C I + NW+ + HT+I
Sbjct 104 --------------LKSLTHIYLYNNPWDCECRDIMYLRNWVAD-HTSI 137
Score = 44.7 bits (104), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 29/112 (26%), Positives = 52/112 (46%), Gaps = 0/112 (0%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLD 81
A ++C+ + +C +++L VP +PT+ L L +NQ+ +L F L L
Sbjct 4 AGCPSQCSCDQTLVNCQNIRLASVPAGIPTDKQRLWLNNNQITKLEPGVFDHLVNLQQLY 63
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
N ++ + + KL L L+L N L + F +LT ++L +N
Sbjct 64 FNSNKLTAIPTGVFDKLTQLTQLDLNDNHLKSIPRGAFDNLKSLTHIYLYNN 115
Score = 33.9 bits (76), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 14/120 (12%)
Query 112 SQLS-DKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
SQ S D+T C N+ L + I P KQ+ L L++N ++ + G L
Sbjct 8 SQCSCDQTLVNCQNI-RLASVPAGI------PTDKQR----LWLNNNQITKLEPGVFDHL 56
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NLQ+L ++NK+ A+ + D + L +L+L+ N +K G F + L ++L N
Sbjct 57 VNLQQLYFNSNKLTAIPTGVFDKL--TQLTQLDLNDNHLKSIPRGAFDNLKSLTHIYLYN 114
>2r9u_D D Variable lymphocyte receptor
Length=174
Score = 46.6 bits (109), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 49/109 (45%), Gaps = 31/109 (28%)
Query 565 HILNLE-----SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQK 619
H++NL+ SN IP VF L +L +DL N+L ++P F+N
Sbjct 55 HLVNLQQLYFNSNKLTAIPTGVFDKLTQLTQLDLNDNHLKSIPRGAFDN----------- 103
Query 620 NLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
++LT + + NP+DC C I + NW+ + HT+I
Sbjct 104 --------------LKSLTHIYLYNNPWDCECRDIMYLRNWVAD-HTSI 137
Score = 44.7 bits (104), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 29/112 (26%), Positives = 52/112 (46%), Gaps = 0/112 (0%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLD 81
A ++C+ + +C +++L VP +PT+ L L +NQ+ +L F L L
Sbjct 4 AGCPSQCSCDQTLVNCQNIRLASVPAGIPTDKQRLWLNNNQITKLEPGVFDHLVNLQQLY 63
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
N ++ + + KL L L+L N L + F +LT ++L +N
Sbjct 64 FNSNKLTAIPTGVFDKLTQLTQLDLNDNHLKSIPRGAFDNLKSLTHIYLYNN 115
Score = 33.9 bits (76), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 14/120 (12%)
Query 112 SQLS-DKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
SQ S D+T C N+ L + I P KQ+ L L++N ++ + G L
Sbjct 8 SQCSCDQTLVNCQNI-RLASVPAGI------PTDKQR----LWLNNNQITKLEPGVFDHL 56
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NLQ+L ++NK+ A+ + D + L +L+L+ N +K G F + L ++L N
Sbjct 57 VNLQQLYFNSNKLTAIPTGVFDKL--TQLTQLDLNDNHLKSIPRGAFDNLKSLTHIYLYN 114
>2r9u_C C Variable lymphocyte receptor
Length=174
Score = 46.6 bits (109), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 31/109 (28%), Positives = 49/109 (45%), Gaps = 31/109 (28%)
Query 565 HILNLE-----SNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQK 619
H++NL+ SN IP VF L +L +DL N+L ++P F+N
Sbjct 55 HLVNLQQLYFNSNKLTAIPTGVFDKLTQLTQLDLNDNHLKSIPRGAFDN----------- 103
Query 620 NLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNI 668
++LT + + NP+DC C I + NW+ + HT+I
Sbjct 104 --------------LKSLTHIYLYNNPWDCECRDIMYLRNWVAD-HTSI 137
Score = 44.7 bits (104), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 29/112 (26%), Positives = 52/112 (46%), Gaps = 0/112 (0%)
Query 22 ASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLD 81
A ++C+ + +C +++L VP +PT+ L L +NQ+ +L F L L
Sbjct 4 AGCPSQCSCDQTLVNCQNIRLASVPAGIPTDKQRLWLNNNQITKLEPGVFDHLVNLQQLY 63
Query 82 VGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
N ++ + + KL L L+L N L + F +LT ++L +N
Sbjct 64 FNSNKLTAIPTGVFDKLTQLTQLDLNDNHLKSIPRGAFDNLKSLTHIYLYNN 115
Score = 33.9 bits (76), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 14/120 (12%)
Query 112 SQLS-DKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
SQ S D+T C N+ L + I P KQ+ L L++N ++ + G L
Sbjct 8 SQCSCDQTLVNCQNI-RLASVPAGI------PTDKQR----LWLNNNQITKLEPGVFDHL 56
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
NLQ+L ++NK+ A+ + D + L +L+L+ N +K G F + L ++L N
Sbjct 57 VNLQQLYFNSNKLTAIPTGVFDKL--TQLTQLDLNDNHLKSIPRGAFDNLKSLTHIYLYN 114
>7odk_B BBB Receptor-like protein kinase HSL1
Length=617
Score = 48.5 bits (114), Expect = 3e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>4r58_D D Leucine Rich Repeat protein
Length=220
Score = 46.6 bits (109), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 58/185 (31%), Positives = 82/185 (44%), Gaps = 47/185 (25%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L+ NKI+ I A L +L LDL N I + L+N+ ++
Sbjct 65 LKTLKLSNNKITDIS--ALKQLNNLGWLDLSNNGI------TDISALKNLASLH-----T 111
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
L L+ N + ALKN+D NL LDLSNN I +I+ L+
Sbjct 112 LDLSNNGITDIS----------ALKNLD----------NLHTLDLSNNGITDIS--ALKN 149
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L+ L LDL +N + I LK L+ LH L+L +NG +I K+L L
Sbjct 150 LDNLHTLDLSNNGIT----------DISALKNLTSLHTLDLSNNGITDIS--ALKNLDNL 197
Query 589 KIIDL 593
+ +DL
Sbjct 198 ETLDL 202
Score = 43.9 bits (102), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 49/143 (34%), Positives = 67/143 (47%), Gaps = 22/143 (15%)
Query 498 SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF 557
S Q L NL L LSNN I +I+ L+ L L LDL +N + I
Sbjct 55 SVQGIQYLPNLKTLKLSNNKITDIS--ALKQLNNLGWLDLSNNGIT----------DISA 102
Query 558 LKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
LK L+ LH L+L +NG +I K+L L +DL N + + A N +L +L+L
Sbjct 103 LKNLASLHTLDLSNNGITDIS--ALKNLDNLHTLDLSNNGITDISA--LKNLDNLHTLDL 158
Query 618 QKNLITSVEKKVFGPAFRNLTEL 640
N IT + A +NLT L
Sbjct 159 SNNGITDI------SALKNLTSL 175
Score = 37.7 bits (86), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 78/175 (45%), Gaps = 31/175 (18%)
Query 62 QLRRLPAANFTRYSQLTSLDVGFNTISKLEP-ELCQKLPMLKVLNLQHNELSQLSD---- 116
L++ + ++L S+D S ++ + Q LP LK L L +N+++ +S
Sbjct 25 NLKKKSVTDAVTQNELNSIDQIIANNSDIKSVQGIQYLPNLKTLKLSNNKITDISALKQL 84
Query 117 -------------KTFAFCTNLTELHLMSNSIQKIKNNPFVKQ-KNLITLDLSHNGLSST 162
+ NL LH + S I + +K NL TLDLS+NG+ T
Sbjct 85 NNLGWLDLSNNGITDISALKNLASLHTLDLSNNGITDISALKNLDNLHTLDLSNNGI--T 142
Query 163 KLGTQVQLENLQELLLSNN---KIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ L+NL L LSNN I ALK+ +SL L+LS+N I + S
Sbjct 143 DISALKNLDNLHTLDLSNNGITDISALKNL-------TSLHTLDLSNNGITDISA 190
>4r58_B B Leucine Rich Repeat protein
Length=220
Score = 46.6 bits (109), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 58/185 (31%), Positives = 82/185 (44%), Gaps = 47/185 (25%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L+ NKI+ I A L +L LDL N I + L+N+ ++
Sbjct 65 LKTLKLSNNKITDIS--ALKQLNNLGWLDLSNNGI------TDISALKNLASLH-----T 111
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
L L+ N + ALKN+D NL LDLSNN I +I+ L+
Sbjct 112 LDLSNNGITDIS----------ALKNLD----------NLHTLDLSNNGITDIS--ALKN 149
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L+ L LDL +N + I LK L+ LH L+L +NG +I K+L L
Sbjct 150 LDNLHTLDLSNNGIT----------DISALKNLTSLHTLDLSNNGITDIS--ALKNLDNL 197
Query 589 KIIDL 593
+ +DL
Sbjct 198 ETLDL 202
Score = 43.9 bits (102), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 49/143 (34%), Positives = 67/143 (47%), Gaps = 22/143 (15%)
Query 498 SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF 557
S Q L NL L LSNN I +I+ L+ L L LDL +N + I
Sbjct 55 SVQGIQYLPNLKTLKLSNNKITDIS--ALKQLNNLGWLDLSNNGIT----------DISA 102
Query 558 LKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
LK L+ LH L+L +NG +I K+L L +DL N + + A N +L +L+L
Sbjct 103 LKNLASLHTLDLSNNGITDIS--ALKNLDNLHTLDLSNNGITDISA--LKNLDNLHTLDL 158
Query 618 QKNLITSVEKKVFGPAFRNLTEL 640
N IT + A +NLT L
Sbjct 159 SNNGITDI------SALKNLTSL 175
Score = 37.7 bits (86), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 78/175 (45%), Gaps = 31/175 (18%)
Query 62 QLRRLPAANFTRYSQLTSLDVGFNTISKLEP-ELCQKLPMLKVLNLQHNELSQLSD---- 116
L++ + ++L S+D S ++ + Q LP LK L L +N+++ +S
Sbjct 25 NLKKKSVTDAVTQNELNSIDQIIANNSDIKSVQGIQYLPNLKTLKLSNNKITDISALKQL 84
Query 117 -------------KTFAFCTNLTELHLMSNSIQKIKNNPFVKQ-KNLITLDLSHNGLSST 162
+ NL LH + S I + +K NL TLDLS+NG+ T
Sbjct 85 NNLGWLDLSNNGITDISALKNLASLHTLDLSNNGITDISALKNLDNLHTLDLSNNGI--T 142
Query 163 KLGTQVQLENLQELLLSNN---KIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ L+NL L LSNN I ALK+ +SL L+LS+N I + S
Sbjct 143 DISALKNLDNLHTLDLSNNGITDISALKNL-------TSLHTLDLSNNGITDISA 190
>4r58_A A Leucine Rich Repeat protein
Length=220
Score = 46.6 bits (109), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 58/185 (31%), Positives = 82/185 (44%), Gaps = 47/185 (25%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L+ NKI+ I A L +L LDL N I + L+N+ ++
Sbjct 65 LKTLKLSNNKITDIS--ALKQLNNLGWLDLSNNGI------TDISALKNLASLH-----T 111
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
L L+ N + ALKN+D NL LDLSNN I +I+ L+
Sbjct 112 LDLSNNGITDIS----------ALKNLD----------NLHTLDLSNNGITDIS--ALKN 149
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L+ L LDL +N + I LK L+ LH L+L +NG +I K+L L
Sbjct 150 LDNLHTLDLSNNGIT----------DISALKNLTSLHTLDLSNNGITDIS--ALKNLDNL 197
Query 589 KIIDL 593
+ +DL
Sbjct 198 ETLDL 202
Score = 43.9 bits (102), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 49/143 (34%), Positives = 67/143 (47%), Gaps = 22/143 (15%)
Query 498 SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF 557
S Q L NL L LSNN I +I+ L+ L L LDL +N + I
Sbjct 55 SVQGIQYLPNLKTLKLSNNKITDIS--ALKQLNNLGWLDLSNNGIT----------DISA 102
Query 558 LKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
LK L+ LH L+L +NG +I K+L L +DL N + + A N +L +L+L
Sbjct 103 LKNLASLHTLDLSNNGITDIS--ALKNLDNLHTLDLSNNGITDISA--LKNLDNLHTLDL 158
Query 618 QKNLITSVEKKVFGPAFRNLTEL 640
N IT + A +NLT L
Sbjct 159 SNNGITDI------SALKNLTSL 175
Score = 37.7 bits (86), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 78/175 (45%), Gaps = 31/175 (18%)
Query 62 QLRRLPAANFTRYSQLTSLDVGFNTISKLEP-ELCQKLPMLKVLNLQHNELSQLSD---- 116
L++ + ++L S+D S ++ + Q LP LK L L +N+++ +S
Sbjct 25 NLKKKSVTDAVTQNELNSIDQIIANNSDIKSVQGIQYLPNLKTLKLSNNKITDISALKQL 84
Query 117 -------------KTFAFCTNLTELHLMSNSIQKIKNNPFVKQ-KNLITLDLSHNGLSST 162
+ NL LH + S I + +K NL TLDLS+NG+ T
Sbjct 85 NNLGWLDLSNNGITDISALKNLASLHTLDLSNNGITDISALKNLDNLHTLDLSNNGI--T 142
Query 163 KLGTQVQLENLQELLLSNN---KIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ L+NL L LSNN I ALK+ +SL L+LS+N I + S
Sbjct 143 DISALKNLDNLHTLDLSNNGITDISALKNL-------TSLHTLDLSNNGITDISA 190
>4r58_C C Leucine Rich Repeat protein
Length=220
Score = 46.6 bits (109), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 58/185 (31%), Positives = 82/185 (44%), Gaps = 47/185 (25%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L+ NKI+ I A L +L LDL N I + L+N+ ++
Sbjct 65 LKTLKLSNNKITDIS--ALKQLNNLGWLDLSNNGI------TDISALKNLASLH-----T 111
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
L L+ N + ALKN+D NL LDLSNN I +I+ L+
Sbjct 112 LDLSNNGITDIS----------ALKNLD----------NLHTLDLSNNGITDIS--ALKN 149
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
L+ L LDL +N + I LK L+ LH L+L +NG +I K+L L
Sbjct 150 LDNLHTLDLSNNGIT----------DISALKNLTSLHTLDLSNNGITDIS--ALKNLDNL 197
Query 589 KIIDL 593
+ +DL
Sbjct 198 ETLDL 202
Score = 43.9 bits (102), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 49/143 (34%), Positives = 67/143 (47%), Gaps = 22/143 (15%)
Query 498 SPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYF 557
S Q L NL L LSNN I +I+ L+ L L LDL +N + I
Sbjct 55 SVQGIQYLPNLKTLKLSNNKITDIS--ALKQLNNLGWLDLSNNGIT----------DISA 102
Query 558 LKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
LK L+ LH L+L +NG +I K+L L +DL N + + A N +L +L+L
Sbjct 103 LKNLASLHTLDLSNNGITDIS--ALKNLDNLHTLDLSNNGITDISA--LKNLDNLHTLDL 158
Query 618 QKNLITSVEKKVFGPAFRNLTEL 640
N IT + A +NLT L
Sbjct 159 SNNGITDI------SALKNLTSL 175
Score = 37.7 bits (86), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 51/175 (29%), Positives = 78/175 (45%), Gaps = 31/175 (18%)
Query 62 QLRRLPAANFTRYSQLTSLDVGFNTISKLEP-ELCQKLPMLKVLNLQHNELSQLSD---- 116
L++ + ++L S+D S ++ + Q LP LK L L +N+++ +S
Sbjct 25 NLKKKSVTDAVTQNELNSIDQIIANNSDIKSVQGIQYLPNLKTLKLSNNKITDISALKQL 84
Query 117 -------------KTFAFCTNLTELHLMSNSIQKIKNNPFVKQ-KNLITLDLSHNGLSST 162
+ NL LH + S I + +K NL TLDLS+NG+ T
Sbjct 85 NNLGWLDLSNNGITDISALKNLASLHTLDLSNNGITDISALKNLDNLHTLDLSNNGI--T 142
Query 163 KLGTQVQLENLQELLLSNN---KIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ L+NL L LSNN I ALK+ +SL L+LS+N I + S
Sbjct 143 DISALKNLDNLHTLDLSNNGITDISALKNL-------TSLHTLDLSNNGITDISA 190
>3a79_B B Toll-like receptor 6, Variable lymphocyte receptor B
Length=562
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 55/188 (29%), Positives = 87/188 (46%), Gaps = 35/188 (19%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEG---LEKLEILDLQHNNLARLWKHANPGGPI 555
PSP + T L+ + N D + +G L++L+ L LQ N L +K A +
Sbjct 350 PSP----SSFTFLNFTQNVFT---DSVFQGCSTLKRLQTLILQRNGLKNFFKVALMTKNM 402
Query 556 YFLKGL--------SHLH-----------ILNLESNGFDEIPVEVFKDLF-ELKIIDLGL 595
L+ L SH + +LNL SN VF+ L ++K++DL
Sbjct 403 SSLETLDVSLNSLNSHAYDRTCAWAESILVLNLSSNMLTG---SVFRCLPPKVKVLDLHN 459
Query 596 NNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIA 655
N + ++P V + Q +L+ LN+ N + SV VF +L + + NP+DCTC I
Sbjct 460 NRIMSIPKDVTHLQ-ALQELNVASNQLKSVPDGVFD-RLTSLQYIWLHDNPWDCTCPGIR 517
Query 656 WFVNWINE 663
+ WIN+
Sbjct 518 YLSEWINK 525
Score = 39.7 bits (91), Expect = 0.17, Method: Compositional matrix adjust.
Identities = 37/124 (30%), Positives = 51/124 (41%), Gaps = 27/124 (22%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+ D S+ LT VP DLP L+L+ N + S+L D+ F
Sbjct 35 MVDYSNRNLTHVPKDLPPRTKALSLSQNSI-----------SELRMPDISF--------- 74
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
L L+VL L HN + L F F +L L + N +Q I P ++ LD
Sbjct 75 ----LSELRVLRLSHNRIRSLDFHVFLFNQDLEYLDVSHNRLQNISCCPMASLRH---LD 127
Query 154 LSHN 157
LS N
Sbjct 128 LSFN 131
>7ogo_D DDD Receptor-like protein kinase HSL1
Length=617
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>7ogu_J JJJ Receptor-like protein kinase HSL1
Length=617
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>7ogq_A AAA Receptor-like protein kinase HSL1
Length=617
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>7odv_D DDD Receptor-like protein kinase HSL1
Length=617
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>7n6g_ZF 6E FAP246
Length=1138
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 41/127 (32%), Positives = 69/127 (54%), Gaps = 11/127 (9%)
Query 37 CSHLKLTQVPDDLPTNIT---VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+H +L +V + L T++T VL+L+HN+L + R + L L +G N + LEP
Sbjct 170 AAHNRLERVGEGL-TSLTLLKVLDLSHNRL--VSVRGLERCANLRELRLGHNALQSLEP- 225
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI-TL 152
L L+VL++ HN L+QLS A ++L L + N + +++ V+ +L+ TL
Sbjct 226 -LAGLSQLQVLDVSHNRLAQLSGA--AGLSSLRTLDVSCNRLGRLEELAVVRGASLLGTL 282
Query 153 DLSHNGL 159
D+ N L
Sbjct 283 DVRGNPL 289
Score = 42.0 bits (97), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 38/147 (26%), Positives = 64/147 (44%), Gaps = 15/147 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
P LT L ++N + + + L L L++LDL HN L + L+
Sbjct 159 LSPFSRLTSLSAAHNRLERVGEG-LTSLTLLKVLDLSHNRLVS----------VRGLERC 207
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
++L L L N + E L +L+++D+ N L L + SL++L++ N
Sbjct 208 ANLRELRLGHNALQSL--EPLAGLSQLQVLDVSHNRLAQLSGAA--GLSSLRTLDVSCNR 263
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPFD 648
+ +E+ L LD+R NP D
Sbjct 264 LGRLEELAVVRGASLLGTLDVRGNPLD 290
Score = 34.3 bits (77), Expect = 7.6, Method: Compositional matrix adjust.
Identities = 60/242 (25%), Positives = 96/242 (40%), Gaps = 46/242 (19%)
Query 383 YLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE 442
YL+LS + T L + + H L L L N++ +E + L HL +D+ N+
Sbjct 70 YLTLSLTGTDL--ANADVLGAFPH--LQTLVLRDNRL--VELRGLAALRHLTAVDVSGNK 123
Query 443 IGQ----ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS 498
+ Q L G N+ S N L + R+ L P RL A ++
Sbjct 124 LTQVLDLRLPADGASGPTNLRSADFSRNA-LDMLRD---LSP-FSRLTSLSAAHNRLERV 178
Query 499 PSPFQPLRNLTILDLSNNNIANIND--------------------DMLEGLEKLEILDLQ 538
L L +LDLS+N + ++ + L GL +L++LD+
Sbjct 179 GEGLTSLTLLKVLDLSHNRLVSVRGLERCANLRELRLGHNALQSLEPLAGLSQLQVLDVS 238
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKIIDLGLNN 597
HN LA+L A GLS L L++ N + + V + L +D+ N
Sbjct 239 HNRLAQLSGAA----------GLSSLRTLDVSCNRLGRLEELAVVRGASLLGTLDVRGNP 288
Query 598 LN 599
L+
Sbjct 289 LD 290
>7n6g_AG 6F FAP246
Length=1138
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 41/127 (32%), Positives = 69/127 (54%), Gaps = 11/127 (9%)
Query 37 CSHLKLTQVPDDLPTNIT---VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+H +L +V + L T++T VL+L+HN+L + R + L L +G N + LEP
Sbjct 170 AAHNRLERVGEGL-TSLTLLKVLDLSHNRL--VSVRGLERCANLRELRLGHNALQSLEP- 225
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI-TL 152
L L+VL++ HN L+QLS A ++L L + N + +++ V+ +L+ TL
Sbjct 226 -LAGLSQLQVLDVSHNRLAQLSGA--AGLSSLRTLDVSCNRLGRLEELAVVRGASLLGTL 282
Query 153 DLSHNGL 159
D+ N L
Sbjct 283 DVRGNPL 289
Score = 42.0 bits (97), Expect = 0.032, Method: Compositional matrix adjust.
Identities = 38/147 (26%), Positives = 64/147 (44%), Gaps = 15/147 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
P LT L ++N + + + L L L++LDL HN L + L+
Sbjct 159 LSPFSRLTSLSAAHNRLERVGEG-LTSLTLLKVLDLSHNRLVS----------VRGLERC 207
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
++L L L N + E L +L+++D+ N L L + SL++L++ N
Sbjct 208 ANLRELRLGHNALQSL--EPLAGLSQLQVLDVSHNRLAQLSGAA--GLSSLRTLDVSCNR 263
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPFD 648
+ +E+ L LD+R NP D
Sbjct 264 LGRLEELAVVRGASLLGTLDVRGNPLD 290
Score = 34.3 bits (77), Expect = 7.6, Method: Compositional matrix adjust.
Identities = 60/242 (25%), Positives = 96/242 (40%), Gaps = 46/242 (19%)
Query 383 YLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE 442
YL+LS + T L + + H L L L N++ +E + L HL +D+ N+
Sbjct 70 YLTLSLTGTDL--ANADVLGAFPH--LQTLVLRDNRL--VELRGLAALRHLTAVDVSGNK 123
Query 443 IGQ----ELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS 498
+ Q L G N+ S N L + R+ L P RL A ++
Sbjct 124 LTQVLDLRLPADGASGPTNLRSADFSRNA-LDMLRD---LSP-FSRLTSLSAAHNRLERV 178
Query 499 PSPFQPLRNLTILDLSNNNIANIND--------------------DMLEGLEKLEILDLQ 538
L L +LDLS+N + ++ + L GL +L++LD+
Sbjct 179 GEGLTSLTLLKVLDLSHNRLVSVRGLERCANLRELRLGHNALQSLEPLAGLSQLQVLDVS 238
Query 539 HNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEI-PVEVFKDLFELKIIDLGLNN 597
HN LA+L A GLS L L++ N + + V + L +D+ N
Sbjct 239 HNRLAQLSGAA----------GLSSLRTLDVSCNRLGRLEELAVVRGASLLGTLDVRGNP 288
Query 598 LN 599
L+
Sbjct 289 LD 290
>7ogo_A AAA Receptor-like protein kinase HSL1
Length=617
Score = 48.1 bits (113), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>7ogz_D DDD Receptor-like protein kinase HSL1
Length=617
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>7ogu_D DDD Receptor-like protein kinase HSL1
Length=617
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>7ogu_G GGG Receptor-like protein kinase HSL1
Length=617
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>7ogu_A AAA Receptor-like protein kinase HSL1
Length=617
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>7odv_A AAA Receptor-like protein kinase HSL1
Length=617
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>7odk_A AAA Receptor-like protein kinase HSL1
Length=617
Score = 47.8 bits (112), Expect = 5e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>7ogz_A AAA Receptor-like protein kinase HSL1
Length=617
Score = 47.8 bits (112), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 131/489 (27%), Positives = 196/489 (40%), Gaps = 76/489 (16%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPM 100
+L Q D+PT + L+LT N A+F ++ L L + +N + P +
Sbjct 112 ELPQTLADIPT-LVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIST 170
Query 101 LKVLNLQHNELSQLS-DKTFAFCTN-----LTELHLMSNSIQKIKNNPFVKQKNLITLDL 154
LK+LNL +N S F TN LTE HL + +I ++ + L+ LDL
Sbjct 171 LKMLNLSYNPFSPSRIPPEFGNLTNLEVMWLTECHL----VGQIPDS-LGQLSKLVDLDL 225
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
+ N L + L N+ ++ L NN + EL SL+ L+ S NQ+ P
Sbjct 226 ALNDLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLK--SLRLLDASMNQLTGKIP 283
Query 215 G--CFHAIGRLFGLFLNNVQ--------LGPSLTEKLCL--ELANTSIRNLSLSNSQLST 262
C + L L+ NN++ L P+L E L ++L L++
Sbjct 284 DELCRVPLESL-NLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSP---- 338
Query 263 TSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF 322
L+W LD+S N + +LE + +N+ + SL
Sbjct 339 --------LRW-----LDVSENEFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADC- 384
Query 323 NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLK 382
RS T+ ++ F L + L + +N G S G NL
Sbjct 385 --------RSLTRIRLAYNRFSGSVPTGFWGLPHVNLLELVNNSFSGEISKSIGGASNLS 436
Query 383 YLSLSNS-FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
L LSN+ FT E SL + L+ L+ + NK S D+ LG L LDL N
Sbjct 437 LLILSNNEFTGSLP---EEIGSLDN--LNQLSASGNKFSGSLPDSLMSLGELGTLDLHGN 491
Query 442 EIGQELTG--QEWRGL------ENIF------EI-YLSYNKYLQLTRNSF-ALVP-SLQR 484
+ ELT + W+ L +N F EI LS YL L+ N F +P SLQ
Sbjct 492 QFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGSLSVLNYLDLSGNMFSGKIPVSLQS 551
Query 485 LMLRRVALK 493
L L ++ L
Sbjct 552 LKLNQLNLS 560
>2z80_B B Toll-like receptor 2, Variable lymphocyte receptor B
Length=353
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 78/281 (28%), Positives = 115/281 (41%), Gaps = 55/281 (20%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L LT N I+ IE D+FS LG LE LDL N + L+ ++ L ++ + L N Y
Sbjct 78 LQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSN-LSSSWFKPLSSLTFLNLLGNPY 136
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
L S L L +L + RV N+D T + + A + LE
Sbjct 137 KTLGETS--LFSHLTKLQILRVG--NMD------------TFTKIQRKDFAGLT--FLEE 178
Query 529 LEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFEL 588
LE ++ DLQ L N I +K HIL LE F ++ V + EL
Sbjct 179 LE-IDASDLQSYEPKSLKSIQNVSHLILHMKQ----HILLLEI--FVDVTSSV--ECLEL 229
Query 589 KIIDLG--------------------LNNLNTLPASVFN-----NQVS-LKSLNLQKNLI 622
+ DL N+ S+F NQ+S L L +N +
Sbjct 230 RDTDLDTFHFSXXXXXXXNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFSRNQL 289
Query 623 TSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINE 663
SV +F +L ++ + NP+DC+C I + W+N+
Sbjct 290 KSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLSRWLNK 329
Score = 42.0 bits (97), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 41/155 (26%), Positives = 73/155 (47%), Gaps = 19/155 (12%)
Query 249 SIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
++++L LSN++++ SN+ + NL L L+ N +N + DSF+ L LE+ L YN
Sbjct 53 AVKSLDLSNNRITYISNSDLQ--RCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYN 110
Query 309 NIQHLFSHSLHGLFNVRYLNLKRS-------------FTKQSI----SLASLPKIDDFSF 351
+ +L S L ++ +LNL + TK I ++ + KI F
Sbjct 111 YLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDF 170
Query 352 QWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
L LE L ++ +D+ + + N+ +L L
Sbjct 171 AGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLIL 205
Score = 39.3 bits (90), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 45/181 (25%), Positives = 78/181 (43%), Gaps = 31/181 (17%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K L+L +N ++ +S+ C NL L L SN I I+ + F +L LDLS+N LS
Sbjct 54 VKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLS 113
Query 161 STK---------------LGTQVQLENLQELLLSNNKIQALKSEELDIFAN--------- 196
+ LG + L K+Q L+ +D F
Sbjct 114 NLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGL 173
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ------LGPSLTEKL-CLELANTS 249
+ L++LE+ ++ ++ + P +I + L L+ Q + +T + CLEL +T
Sbjct 174 TFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTD 233
Query 250 I 250
+
Sbjct 234 L 234
Score = 33.9 bits (76), Expect = 8.0, Method: Compositional matrix adjust.
Identities = 42/167 (25%), Positives = 76/167 (46%), Gaps = 12/167 (7%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L LT N + + +F+ L LD+ +N +S L + L L LNL N
Sbjct 77 NLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWFKPLSSLTFLNLLGNPY 136
Query 112 SQLSDKTFAFCTNLTELHLMS----NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQ 167
L + + ++LT+L ++ ++ KI+ F L L++ + L S + +
Sbjct 137 KTLGETSLF--SHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSYEPKSL 194
Query 168 VQLENLQELLLSNNKIQALKSEELDIFAN--SSLKKLELSSNQIKEF 212
++N+ L+L + L L+IF + SS++ LEL + F
Sbjct 195 KSIQNVSHLILHMKQHILL----LEIFVDVTSSVECLELRDTDLDTF 237
>8ben_C C Volume-regulated anion channel subunit LRRC8C
Length=412
Score = 47.4 bits (111), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 85/307 (28%), Positives = 148/307 (48%), Gaps = 24/307 (8%)
Query 345 KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--LRTLTNETF 401
KI + +LK L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+
Sbjct 88 KIHSAALSFLKENLKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHDISKNVTLESL 146
Query 402 VSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEI 461
L L IL++ N +SKI HL+ + + N+ + + + + N+ E+
Sbjct 147 RDLKS--LKILSIKSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTEL 202
Query 462 YLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI 521
L + ++ F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I
Sbjct 203 ELVHCDLERIPHAVFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYI 260
Query 522 NDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEV 581
+ ++ L LE L HN + L H I + L+L N IP E+
Sbjct 261 -PEHIKKLTSLERLFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI 310
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
L L+ + N + +LP ++ + LK+L + KN ++ + K+ F L+ LD
Sbjct 311 -GVLQSLQYFSITCNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLD 366
Query 642 MRFNPFD 648
++ N F+
Sbjct 367 IKGNHFE 373
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 59/200 (30%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 197 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 255
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + T+L L N ++ + ++ F+ K + LDLS+N + ++G
Sbjct 256 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 312
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF 227
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LF
Sbjct 313 --LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LF 361
Query 228 LNNVQLGPSLTEKLCLELAN 247
L+ + + + E L EL +
Sbjct 362 LSYLDIKGNHFEVLPPELGD 381
>2z80_A A Toll-like receptor 2, Variable lymphocyte receptor B
Length=353
Score = 47.0 bits (110), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 68/266 (26%), Positives = 110/266 (41%), Gaps = 25/266 (9%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L LT N I+ IE D+FS LG LE LDL N + L+ ++ L ++ + L N Y
Sbjct 78 LQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSN-LSSSWFKPLSSLTFLNLLGNPY 136
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDS----SPSPFQPLRNLTILDLSNNNIANINDD 524
L S L L +L + RV N+D+ F L L L++ +++ +
Sbjct 137 KTLGETS--LFSHLTKLQILRVG--NMDTFTKIQRKDFAGLTFLEELEIDASDLQSYEPK 192
Query 525 MLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKD 584
L+ ++ + L L L + F+ S + L L D
Sbjct 193 SLKSIQNVSHLILHMKQHILLLE--------IFVDVTSSVECLELRDTDLDTFHFSXXXX 244
Query 585 LFELKII-DLGLNNLNTLPASVFN-----NQVS-LKSLNLQKNLITSVEKKVFGPAFRNL 637
+I N+ S+F NQ+S L L +N + SV +F +L
Sbjct 245 XXTNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFSRNQLKSVPDGIFD-RLTSL 303
Query 638 TELDMRFNPFDCTCESIAWFVNWINE 663
++ + NP+DC+C I + W+N+
Sbjct 304 QKIWLHTNPWDCSCPRIDYLSRWLNK 329
Score = 42.0 bits (97), Expect = 0.023, Method: Compositional matrix adjust.
Identities = 41/155 (26%), Positives = 73/155 (47%), Gaps = 19/155 (12%)
Query 249 SIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN 308
++++L LSN++++ SN+ + NL L L+ N +N + DSF+ L LE+ L YN
Sbjct 53 AVKSLDLSNNRITYISNSDLQ--RCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYN 110
Query 309 NIQHLFSHSLHGLFNVRYLNLKRS-------------FTKQSI----SLASLPKIDDFSF 351
+ +L S L ++ +LNL + TK I ++ + KI F
Sbjct 111 YLSNLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDF 170
Query 352 QWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSL 386
L LE L ++ +D+ + + N+ +L L
Sbjct 171 AGLTFLEELEIDASDLQSYEPKSLKSIQNVSHLIL 205
Score = 40.8 bits (94), Expect = 0.058, Method: Compositional matrix adjust.
Identities = 61/258 (24%), Positives = 104/258 (40%), Gaps = 50/258 (19%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K L+L +N ++ +S+ C NL L L SN I I+ + F +L LDLS+N LS
Sbjct 54 VKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLS 113
Query 161 STK---------------LGTQVQLENLQELLLSNNKIQALKSEELDIFAN--------- 196
+ LG + L K+Q L+ +D F
Sbjct 114 NLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGL 173
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ------LGPSLTEKL-CLELANTS 249
+ L++LE+ ++ ++ + P +I + L L+ Q + +T + CLEL +T
Sbjct 174 TFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTD 233
Query 250 IRNLSLSNSQLSTTSNT----TFLGLKWTNLTM---------------LDLSYNNLNVVG 290
+ S T++ TF +K T+ ++ L+ S N L V
Sbjct 234 LDTFHFSXXXXXXTNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFSRNQLKSVP 293
Query 291 NDSFAWLPQLEYFFLEYN 308
+ F L L+ +L N
Sbjct 294 DGIFDRLTSLQKIWLHTN 311
Score = 33.9 bits (76), Expect = 8.8, Method: Compositional matrix adjust.
Identities = 42/167 (25%), Positives = 76/167 (46%), Gaps = 12/167 (7%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ L LT N + + +F+ L LD+ +N +S L + L L LNL N
Sbjct 77 NLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLSNLSSSWFKPLSSLTFLNLLGNPY 136
Query 112 SQLSDKTFAFCTNLTELHLMS----NSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQ 167
L + + ++LT+L ++ ++ KI+ F L L++ + L S + +
Sbjct 137 KTLGETSLF--SHLTKLQILRVGNMDTFTKIQRKDFAGLTFLEELEIDASDLQSYEPKSL 194
Query 168 VQLENLQELLLSNNKIQALKSEELDIFAN--SSLKKLELSSNQIKEF 212
++N+ L+L + L L+IF + SS++ LEL + F
Sbjct 195 KSIQNVSHLILHMKQHILL----LEIFVDVTSSVECLELRDTDLDTF 237
>7tvf_E A Leucine-rich repeat protein SHOC-2
Length=582
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 378
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 379 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 433
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 434 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 489
Query 216 CFH 218
H
Sbjct 490 IGH 492
Score = 42.0 bits (97), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 144 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 202
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 203 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 234
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 235 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 287
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 288 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 318
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 371
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 372 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 421
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 422 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 476
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 477 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 530
Score = 39.3 bits (90), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 123 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 180
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 181 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 240
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 241 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 293
Query 207 NQI 209
N++
Sbjct 294 NRL 296
Score = 38.9 bits (89), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 148 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 204
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 205 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 259
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 260 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 319
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 320 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 378
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
>7sqc_KM X3 FAP246
Length=1138
Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 41/127 (32%), Positives = 69/127 (54%), Gaps = 11/127 (9%)
Query 37 CSHLKLTQVPDDLPTNIT---VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+H +L +V + L T++T VL+L+HN+L + R + L L +G N + LEP
Sbjct 170 AAHNRLERVGEGL-TSLTLLKVLDLSHNRL--VSVRGLERCANLRELRLGHNALQSLEP- 225
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI-TL 152
L L+VL++ HN L+QLS A ++L L + N + +++ V+ +L+ TL
Sbjct 226 -LAGLSQLQVLDVSHNRLAQLSGA--AGLSSLRTLDVSCNRLGRLEELAVVRGASLLGTL 282
Query 153 DLSHNGL 159
D+ N L
Sbjct 283 DVRGNPL 289
Score = 42.4 bits (98), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 38/147 (26%), Positives = 64/147 (44%), Gaps = 15/147 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
P LT L ++N + + + L L L++LDL HN L + L+
Sbjct 159 LSPFSRLTSLSAAHNRLERVGEG-LTSLTLLKVLDLSHNRLVS----------VRGLERC 207
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
++L L L N + E L +L+++D+ N L L + SL++L++ N
Sbjct 208 ANLRELRLGHNALQSL--EPLAGLSQLQVLDVSHNRLAQLSGAA--GLSSLRTLDVSCNR 263
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPFD 648
+ +E+ L LD+R NP D
Sbjct 264 LGRLEELAVVRGASLLGTLDVRGNPLD 290
>7sqc_JM X2 FAP246
Length=1138
Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 41/127 (32%), Positives = 69/127 (54%), Gaps = 11/127 (9%)
Query 37 CSHLKLTQVPDDLPTNIT---VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+H +L +V + L T++T VL+L+HN+L + R + L L +G N + LEP
Sbjct 170 AAHNRLERVGEGL-TSLTLLKVLDLSHNRL--VSVRGLERCANLRELRLGHNALQSLEP- 225
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI-TL 152
L L+VL++ HN L+QLS A ++L L + N + +++ V+ +L+ TL
Sbjct 226 -LAGLSQLQVLDVSHNRLAQLSGA--AGLSSLRTLDVSCNRLGRLEELAVVRGASLLGTL 282
Query 153 DLSHNGL 159
D+ N L
Sbjct 283 DVRGNPL 289
Score = 42.4 bits (98), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 38/147 (26%), Positives = 64/147 (44%), Gaps = 15/147 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
P LT L ++N + + + L L L++LDL HN L + L+
Sbjct 159 LSPFSRLTSLSAAHNRLERVGEG-LTSLTLLKVLDLSHNRLVS----------VRGLERC 207
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
++L L L N + E L +L+++D+ N L L + SL++L++ N
Sbjct 208 ANLRELRLGHNALQSL--EPLAGLSQLQVLDVSHNRLAQLSGAA--GLSSLRTLDVSCNR 263
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPFD 648
+ +E+ L LD+R NP D
Sbjct 264 LGRLEELAVVRGASLLGTLDVRGNPLD 290
>7sqc_IM X1 FAP246
Length=1138
Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 41/127 (32%), Positives = 69/127 (54%), Gaps = 11/127 (9%)
Query 37 CSHLKLTQVPDDLPTNIT---VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+H +L +V + L T++T VL+L+HN+L + R + L L +G N + LEP
Sbjct 170 AAHNRLERVGEGL-TSLTLLKVLDLSHNRL--VSVRGLERCANLRELRLGHNALQSLEP- 225
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI-TL 152
L L+VL++ HN L+QLS A ++L L + N + +++ V+ +L+ TL
Sbjct 226 -LAGLSQLQVLDVSHNRLAQLSGA--AGLSSLRTLDVSCNRLGRLEELAVVRGASLLGTL 282
Query 153 DLSHNGL 159
D+ N L
Sbjct 283 DVRGNPL 289
Score = 42.4 bits (98), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 38/147 (26%), Positives = 64/147 (44%), Gaps = 15/147 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
P LT L ++N + + + L L L++LDL HN L + L+
Sbjct 159 LSPFSRLTSLSAAHNRLERVGEG-LTSLTLLKVLDLSHNRLVS----------VRGLERC 207
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
++L L L N + E L +L+++D+ N L L + SL++L++ N
Sbjct 208 ANLRELRLGHNALQSL--EPLAGLSQLQVLDVSHNRLAQLSGAA--GLSSLRTLDVSCNR 263
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPFD 648
+ +E+ L LD+R NP D
Sbjct 264 LGRLEELAVVRGASLLGTLDVRGNPLD 290
>7sqc_HM X0 FAP246
Length=1138
Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 41/127 (32%), Positives = 69/127 (54%), Gaps = 11/127 (9%)
Query 37 CSHLKLTQVPDDLPTNIT---VLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+H +L +V + L T++T VL+L+HN+L + R + L L +G N + LEP
Sbjct 170 AAHNRLERVGEGL-TSLTLLKVLDLSHNRL--VSVRGLERCANLRELRLGHNALQSLEP- 225
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLI-TL 152
L L+VL++ HN L+QLS A ++L L + N + +++ V+ +L+ TL
Sbjct 226 -LAGLSQLQVLDVSHNRLAQLSGA--AGLSSLRTLDVSCNRLGRLEELAVVRGASLLGTL 282
Query 153 DLSHNGL 159
D+ N L
Sbjct 283 DVRGNPL 289
Score = 42.4 bits (98), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 38/147 (26%), Positives = 64/147 (44%), Gaps = 15/147 (10%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
P LT L ++N + + + L L L++LDL HN L + L+
Sbjct 159 LSPFSRLTSLSAAHNRLERVGEG-LTSLTLLKVLDLSHNRLVS----------VRGLERC 207
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
++L L L N + E L +L+++D+ N L L + SL++L++ N
Sbjct 208 ANLRELRLGHNALQSL--EPLAGLSQLQVLDVSHNRLAQLSGAA--GLSSLRTLDVSCNR 263
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPFD 648
+ +E+ L LD+R NP D
Sbjct 264 LGRLEELAVVRGASLLGTLDVRGNPLD 290
>8drn_B F Volume-regulated anion channel subunit LRRC8C
Length=813
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 85/307 (28%), Positives = 148/307 (48%), Gaps = 24/307 (8%)
Query 345 KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--LRTLTNETF 401
KI + +LK L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+
Sbjct 480 KIHSAALSFLKENLKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHDISKNVTLESL 538
Query 402 VSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEI 461
L L IL++ N +SKI HL+ + + N+ + + + + N+ E+
Sbjct 539 RDLKS--LKILSIKSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTEL 594
Query 462 YLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI 521
L + ++ F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I
Sbjct 595 ELVHCDLERIPHAVFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYI 652
Query 522 NDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEV 581
+ ++ L LE L HN + L H I + L+L N IP E+
Sbjct 653 PEH-IKKLTSLERLFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI 702
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
L L+ + N + +LP ++ + LK+L + KN ++ + K+ F L+ LD
Sbjct 703 -GVLQSLQYFSITCNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLD 758
Query 642 MRFNPFD 648
++ N F+
Sbjct 759 IKGNHFE 765
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 59/200 (30%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 589 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 647
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + T+L L N ++ + ++ F+ K + LDLS+N + ++G
Sbjct 648 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 704
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF 227
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LF
Sbjct 705 --LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LF 753
Query 228 LNNVQLGPSLTEKLCLELAN 247
L+ + + + E L EL +
Sbjct 754 LSYLDIKGNHFEVLPPELGD 773
>8f7d_B F Volume-regulated anion channel subunit LRRC8C
Length=813
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 85/307 (28%), Positives = 148/307 (48%), Gaps = 24/307 (8%)
Query 345 KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--LRTLTNETF 401
KI + +LK L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+
Sbjct 480 KIHSAALSFLKENLKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHDISKNVTLESL 538
Query 402 VSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEI 461
L L IL++ N +SKI HL+ + + N+ + + + + N+ E+
Sbjct 539 RDLKS--LKILSIKSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTEL 594
Query 462 YLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI 521
L + ++ F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I
Sbjct 595 ELVHCDLERIPHAVFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYI 652
Query 522 NDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEV 581
+ ++ L LE L HN + L H I + L+L N IP E+
Sbjct 653 PEH-IKKLTSLERLFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI 702
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
L L+ + N + +LP ++ + LK+L + KN ++ + K+ F L+ LD
Sbjct 703 -GVLQSLQYFSITCNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLD 758
Query 642 MRFNPFD 648
++ N F+
Sbjct 759 IKGNHFE 765
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 59/200 (30%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 589 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 647
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + T+L L N ++ + ++ F+ K + LDLS+N + ++G
Sbjct 648 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 704
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF 227
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LF
Sbjct 705 --LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LF 753
Query 228 LNNVQLGPSLTEKLCLELAN 247
L+ + + + E L EL +
Sbjct 754 LSYLDIKGNHFEVLPPELGD 773
>8dra_C F Volume-regulated anion channel subunit LRRC8C
Length=813
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 85/307 (28%), Positives = 148/307 (48%), Gaps = 24/307 (8%)
Query 345 KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--LRTLTNETF 401
KI + +LK L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+
Sbjct 480 KIHSAALSFLKENLKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHDISKNVTLESL 538
Query 402 VSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEI 461
L L IL++ N +SKI HL+ + + N+ + + + + N+ E+
Sbjct 539 RDLKS--LKILSIKSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTEL 594
Query 462 YLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI 521
L + ++ F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I
Sbjct 595 ELVHCDLERIPHAVFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYI 652
Query 522 NDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEV 581
+ ++ L LE L HN + L H I + L+L N IP E+
Sbjct 653 PEH-IKKLTSLERLFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI 702
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
L L+ + N + +LP ++ + LK+L + KN ++ + K+ F L+ LD
Sbjct 703 -GVLQSLQYFSITCNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLD 758
Query 642 MRFNPFD 648
++ N F+
Sbjct 759 IKGNHFE 765
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 59/200 (30%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 589 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 647
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + T+L L N ++ + ++ F+ K + LDLS+N + ++G
Sbjct 648 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 704
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF 227
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LF
Sbjct 705 --LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LF 753
Query 228 LNNVQLGPSLTEKLCLELAN 247
L+ + + + E L EL +
Sbjct 754 LSYLDIKGNHFEVLPPELGD 773
>8f75_C F Volume-regulated anion channel subunit LRRC8C
Length=813
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 85/307 (28%), Positives = 148/307 (48%), Gaps = 24/307 (8%)
Query 345 KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTS--LRTLTNETF 401
KI + +LK L+ L+++ +D+ + M+ GL NL+ L L S + + +T E+
Sbjct 480 KIHSAALSFLKENLKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHDISKNVTLESL 538
Query 402 VSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEI 461
L L IL++ N +SKI HL+ + + N+ + + + + N+ E+
Sbjct 539 RDLKS--LKILSIKSN-VSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLKKMTNLTEL 594
Query 462 YLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI 521
L + ++ F+L+ SLQ L L+ LK+++ S FQ LR LT+L L N+IA I
Sbjct 595 ELVHCDLERIPHAVFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKLWYNSIAYI 652
Query 522 NDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEV 581
+ ++ L LE L HN + L H I + L+L N IP E+
Sbjct 653 PEH-IKKLTSLERLFFSHNKVEVLPSHLFLCNKIRY---------LDLSYNDIRFIPPEI 702
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELD 641
L L+ + N + +LP ++ + LK+L + KN ++ + K+ F L+ LD
Sbjct 703 -GVLQSLQYFSITCNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLLF--LSYLD 758
Query 642 MRFNPFD 648
++ N F+
Sbjct 759 IKGNHFE 765
Score = 46.2 bits (108), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 59/200 (30%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 589 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 647
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + T+L L N ++ + ++ F+ K + LDLS+N + ++G
Sbjct 648 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 704
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF 227
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LF
Sbjct 705 --LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LF 753
Query 228 LNNVQLGPSLTEKLCLELAN 247
L+ + + + E L EL +
Sbjct 754 LSYLDIKGNHFEVLPPELGD 773
>7txh_E E Leucine-rich repeat protein SHOC-2
Length=505
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 242 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 301
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 302 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 356
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 357 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 412
Query 216 CFH 218
H
Sbjct 413 IGH 415
Score = 42.0 bits (97), Expect = 0.026, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 67 CLVNLMTLALSENSLTSLPDSLDNLKKLRILDLRHNKLREIPSVVY-RLDSLTTLYLRFN 125
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 126 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 157
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 158 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 210
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 211 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 241
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 242 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 294
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 295 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 344
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 345 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 399
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 400 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 453
Score = 40.0 bits (92), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 46 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRILDLRHNK 103
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 104 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 163
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 164 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 216
Query 207 NQI 209
N++
Sbjct 217 NRL 219
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 71 LMTLALSENSLTSL-PDSLDNLKKLRILDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 127
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 128 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 182
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 183 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 242
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 243 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 301
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 302 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 342
>8glv_AR Eb Flagellar associated protein
Length=1598
Score = 47.8 bits (112), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 41/142 (29%), Positives = 74/142 (52%), Gaps = 7/142 (5%)
Query 42 LTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP 99
LT +PD+L + +L L +NQL+R+PA + R QL D N I K++ + L
Sbjct 64 LTDLPDELEEFRYLRILRLKYNQLKRIPAVVY-RLPQLMVFDASGNRIQKVDDAIGH-LS 121
Query 100 MLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGL 159
+LK L++ NE++ L + + + L L + +N ++ + + + +I +DLS N L
Sbjct 122 LLKELDVSGNEITTLPE-SLSTLPKLEVLQVENNRLELLPES-LGELPGVIKMDLSTNNL 179
Query 160 SSTKLGTQVQLENLQELLLSNN 181
+ QL+ +Q + + NN
Sbjct 180 RYLP-ASMGQLKKVQRIDVGNN 200
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 51/196 (26%), Positives = 88/196 (45%), Gaps = 21/196 (11%)
Query 460 EIYLSYNKY---LQLTRNSFALVPS----LQRLMLRRVALKNVDSSPSPFQPLRNLTILD 512
E+ YN + L+L+ N +P + L + R+ + P+ L L + D
Sbjct 45 ELVKKYNPHITELELSSNDLTDLPDELEEFRYLRILRLKYNQLKRIPAVVYRLPQLMVFD 104
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESN 572
S N I + DD + L L+ LD+ N + L + L L L +L +E+N
Sbjct 105 ASGNRIQKV-DDAIGHLSLLKELDVSGNEITTLPES---------LSTLPKLEVLQVENN 154
Query 573 GFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP 632
+ +P E +L + +DL NNL LPAS+ ++ +++ NL+T V +
Sbjct 155 RLELLP-ESLGELPGVIKMDLSTNNLRYLPASM-GQLKKVQRIDVGNNLLTKVPPSMG-- 210
Query 633 AFRNLTELDMRFNPFD 648
+ L E ++R+N D
Sbjct 211 HLKTLKEFNLRYNHLD 226
>7sd0_A A Leucine-rich repeat protein SHOC-2
Length=585
Score = 47.4 bits (111), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 378
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 379 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 433
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 434 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 489
Query 216 CFH 218
H
Sbjct 490 IGH 492
Score = 41.2 bits (95), Expect = 0.050, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 144 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 202
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 203 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 234
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 235 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 287
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 288 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 318
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 371
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 372 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 421
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 422 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 476
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 477 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 530
Score = 39.3 bits (90), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 123 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 180
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 181 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 240
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 241 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 293
Query 207 NQI 209
N++
Sbjct 294 NRL 296
Score = 38.9 bits (89), Expect = 0.25, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 148 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 204
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 205 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 259
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 260 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 319
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 320 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 378
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
>7txh_B B Leucine-rich repeat protein SHOC-2
Length=505
Score = 47.0 bits (110), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 242 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 301
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 302 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 356
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 357 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 412
Query 216 CFH 218
H
Sbjct 413 IGH 415
Score = 42.4 bits (98), Expect = 0.025, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 67 CLVNLMTLALSENSLTSLPDSLDNLKKLRILDLRHNKLREIPSVVY-RLDSLTTLYLRFN 125
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 126 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 157
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 158 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 210
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 211 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 241
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 242 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 294
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 295 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 344
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 345 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 399
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 400 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 453
Score = 40.0 bits (92), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 46 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRILDLRHNK 103
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 104 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 163
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 164 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 216
Query 207 NQI 209
N++
Sbjct 217 NRL 219
Score = 39.7 bits (91), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 71 LMTLALSENSLTSL-PDSLDNLKKLRILDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 127
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 128 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 182
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 183 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 242
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 243 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 301
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 302 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 342
>7tyg_A A Leucine-rich repeat protein SHOC-2
Length=505
Score = 47.0 bits (110), Expect = 7e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 242 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 301
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 302 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 356
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 357 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 412
Query 216 CFH 218
H
Sbjct 413 IGH 415
Score = 41.2 bits (95), Expect = 0.044, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 67 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 125
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 126 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 157
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 158 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 210
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 211 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 241
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 242 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 294
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 295 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 344
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 345 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 399
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 400 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 453
Score = 39.3 bits (90), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 46 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 103
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 104 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 163
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 164 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 216
Query 207 NQI 209
N++
Sbjct 217 NRL 219
Score = 38.9 bits (89), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 71 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 127
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 128 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 182
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 183 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 242
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 243 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 301
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 302 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 342
>7tyg_B B Leucine-rich repeat protein SHOC-2
Length=505
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 242 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 301
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 302 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 356
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 357 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 412
Query 216 CFH 218
H
Sbjct 413 IGH 415
Score = 41.2 bits (95), Expect = 0.046, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 67 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 125
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 126 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 157
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 158 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 210
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 211 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 241
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 242 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 294
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 295 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 344
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 345 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 399
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 400 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 453
Score = 39.3 bits (90), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 46 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 103
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 104 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 163
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 164 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 216
Query 207 NQI 209
N++
Sbjct 217 NRL 219
Score = 38.9 bits (89), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 71 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 127
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 128 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 182
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 183 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 242
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 243 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 301
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 302 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 342
>7t7a_B B Leucine-rich repeat protein SHOC-2
Length=494
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 232 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 291
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 292 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 346
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 347 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 402
Query 216 CFH 218
H
Sbjct 403 IGH 405
Score = 41.2 bits (95), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 57 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 115
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 116 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 147
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 148 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 200
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 201 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 231
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 232 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 284
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 285 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 334
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 335 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 389
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 390 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 443
Score = 39.3 bits (90), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 36 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 93
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 94 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 153
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 154 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 206
Query 207 NQI 209
N++
Sbjct 207 NRL 209
Score = 38.9 bits (89), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 61 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 117
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 118 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 172
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 173 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 232
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 233 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 291
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 292 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 332
>7t7a_A A Leucine-rich repeat protein SHOC-2
Length=494
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 232 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 291
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 292 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 346
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 347 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 402
Query 216 CFH 218
H
Sbjct 403 IGH 405
Score = 41.2 bits (95), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 57 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 115
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 116 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 147
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 148 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 200
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 201 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 231
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 232 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 284
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 285 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 334
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 335 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 389
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 390 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 443
Score = 39.3 bits (90), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 36 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 93
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 94 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 153
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 154 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 206
Query 207 NQI 209
N++
Sbjct 207 NRL 209
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 61 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 117
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 118 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 172
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 173 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 232
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 233 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 291
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 292 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 332
>7sd1_B B Leucine-rich repeat protein SHOC-2
Length=585
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 378
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 379 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 433
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 434 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 489
Query 216 CFH 218
H
Sbjct 490 IGH 492
Score = 41.2 bits (95), Expect = 0.048, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 144 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 202
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 203 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 234
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 235 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 287
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 288 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 318
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 371
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 372 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 421
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 422 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 476
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 477 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 530
Score = 39.3 bits (90), Expect = 0.22, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 123 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 180
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 181 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 240
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 241 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 293
Query 207 NQI 209
N++
Sbjct 294 NRL 296
Score = 38.9 bits (89), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 148 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 204
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 205 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 259
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 260 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 319
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 320 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 378
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
>6nih_A A Toll-like receptor 1,Variable lymphocyte receptor B
Length=545
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 50/185 (27%), Positives = 82/185 (44%), Gaps = 28/185 (15%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
PS P +L D SNN + + + L +LE L LQ N L L K A + L
Sbjct 344 PSKISPFLHL---DFSNNLLTDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSL 400
Query 559 KGLS-------------------HLHILNLESNGFDEIPVEVFKDLF-ELKIIDLGLNNL 598
+ L L LN+ SN + +F+ L +K++DL N +
Sbjct 401 QQLDISQNSVSYDEKKGDCSWTKSLLSLNMSSNILTDT---IFRCLPPRIKVLDLHSNKI 457
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
++P V + +L+ LN+ N + SV +F +L ++ + NP+DC+C I +
Sbjct 458 KSIPKQVVKLE-ALQELNVASNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLS 515
Query 659 NWINE 663
W+N+
Sbjct 516 RWLNK 520
Score = 39.3 bits (90), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 115/544 (21%), Positives = 222/544 (41%), Gaps = 94/544 (17%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+ D S L VP DL T+LN++ N + L ++ S+L L + N I L+
Sbjct 28 LVDRSKNGLIHVPKDLSQKTTILNISQNYISELWTSDILSLSKLRILIISHNRIQYLDIS 87
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
+ + L+ L+L HN+L ++S NL L L N+ + P K+ ++
Sbjct 88 VFKFNQELEYLDLSHNKLVKISCHP---TVNLKHLDLSFNAFDAL---PICKEFGNMS-Q 140
Query 154 LSHNGLSSTKLGTQVQLE----NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
L GLS+T L L N+ ++LL + K + +
Sbjct 141 LKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKEDP----------------EGL 184
Query 210 KEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT--- 266
++F+ H + F N + L+++ ++ NL LSN + N
Sbjct 185 QDFNTESLHIV------FPTNKEF------HFILDVSVKTVANLELSNIKCVLEDNKCSY 232
Query 267 --TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY----FFLEYNNIQHLFSHSLHG 320
+ L TN + +L+ NN+ N SF + QL + ++ +N++ L G
Sbjct 233 FLSILAKLQTNPKLSNLTLNNIETTWN-SFIRILQLVWHTTVWYFSISNVK------LQG 285
Query 321 LFNVRYLNLKRSFTKQSISLASLPKI--DDFSFQWLKCLE---HLNMEDNDIPGIKSNMF 375
+ R + ++ S+ S+ ++ D F F E ++N+++ + G + M
Sbjct 286 QLDFRDFD----YSGTSLKALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTR--MV 339
Query 376 TGLINLK-----YLSLSNSFTSLRTLTNETFVSLAH-SPLHILNLTKNKISKIE--SDAF 427
L K +L SN+ LT+ F + H + L L L N++ ++ ++
Sbjct 340 HMLCPSKISPFLHLDFSNNL-----LTDTVFENCGHLTELETLILQMNQLKELSKIAEMT 394
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+ + L+ LD+ N + + + +++ + +S N LT F +P R+ +
Sbjct 395 TQMKSLQQLDISQNSVSYDEKKGDCSWTKSLLSLNMSSNI---LTDTIFRCLPP--RIKV 449
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
+ + S P L L L++++N + ++ D + + L L+ ++W
Sbjct 450 LDLHSNKIKSIPKQVVKLEALQELNVASNQLKSVPDGIFDRLTSLQ----------KIWL 499
Query 548 HANP 551
H NP
Sbjct 500 HTNP 503
>2z7x_B B Toll-like receptor 1,Variable lymphocyte receptor B
Length=520
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 50/185 (27%), Positives = 82/185 (44%), Gaps = 28/185 (15%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
PS P +L D SNN + + + L +LE L LQ N L L K A + L
Sbjct 320 PSKISPFLHL---DFSNNLLTDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSL 376
Query 559 KGLS-------------------HLHILNLESNGFDEIPVEVFKDLF-ELKIIDLGLNNL 598
+ L L LN+ SN + +F+ L +K++DL N +
Sbjct 377 QQLDISQNSVSYDEKKGDCSWTKSLLSLNMSSNILTDT---IFRCLPPRIKVLDLHSNKI 433
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
++P V + +L+ LN+ N + SV +F +L ++ + NP+DC+C I +
Sbjct 434 KSIPKQVVKLE-ALQELNVASNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLS 491
Query 659 NWINE 663
W+N+
Sbjct 492 RWLNK 496
Score = 39.3 bits (90), Expect = 0.20, Method: Compositional matrix adjust.
Identities = 115/544 (21%), Positives = 222/544 (41%), Gaps = 94/544 (17%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+ D S L VP DL T+LN++ N + L ++ S+L L + N I L+
Sbjct 4 LVDRSKNGLIHVPKDLSQKTTILNISQNYISELWTSDILSLSKLRILIISHNRIQYLDIS 63
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
+ + L+ L+L HN+L ++S NL L L N+ + P K+ ++
Sbjct 64 VFKFNQELEYLDLSHNKLVKISCHP---TVNLKHLDLSFNAFDAL---PICKEFGNMS-Q 116
Query 154 LSHNGLSSTKLGTQVQLE----NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
L GLS+T L L N+ ++LL + K + +
Sbjct 117 LKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKEDP----------------EGL 160
Query 210 KEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT--- 266
++F+ H + F N + L+++ ++ NL LSN + N
Sbjct 161 QDFNTESLHIV------FPTNKEF------HFILDVSVKTVANLELSNIKCVLEDNKCSY 208
Query 267 --TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY----FFLEYNNIQHLFSHSLHG 320
+ L TN + +L+ NN+ N SF + QL + ++ +N++ L G
Sbjct 209 FLSILAKLQTNPKLSNLTLNNIETTWN-SFIRILQLVWHTTVWYFSISNVK------LQG 261
Query 321 LFNVRYLNLKRSFTKQSISLASLPKI--DDFSFQWLKCLE---HLNMEDNDIPGIKSNMF 375
+ R + ++ S+ S+ ++ D F F E ++N+++ + G + M
Sbjct 262 QLDFRDFD----YSGTSLKALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTR--MV 315
Query 376 TGLINLK-----YLSLSNSFTSLRTLTNETFVSLAH-SPLHILNLTKNKISKIE--SDAF 427
L K +L SN+ LT+ F + H + L L L N++ ++ ++
Sbjct 316 HMLCPSKISPFLHLDFSNNL-----LTDTVFENCGHLTELETLILQMNQLKELSKIAEMT 370
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+ + L+ LD+ N + + + +++ + +S N LT F +P R+ +
Sbjct 371 TQMKSLQQLDISQNSVSYDEKKGDCSWTKSLLSLNMSSNI---LTDTIFRCLPP--RIKV 425
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
+ + S P L L L++++N + ++ D + + L L+ ++W
Sbjct 426 LDLHSNKIKSIPKQVVKLEALQELNVASNQLKSVPDGIFDRLTSLQ----------KIWL 475
Query 548 HANP 551
H NP
Sbjct 476 HTNP 479
>7sd1_C C Leucine-rich repeat protein SHOC-2
Length=585
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 378
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 379 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 433
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 434 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 489
Query 216 CFH 218
H
Sbjct 490 IGH 492
Score = 41.2 bits (95), Expect = 0.053, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 144 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 202
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 203 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 234
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 235 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 287
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 288 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 318
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 371
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 372 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 421
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 422 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 476
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 477 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 530
Score = 39.3 bits (90), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 123 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 180
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 181 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 240
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 241 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 293
Query 207 NQI 209
N++
Sbjct 294 NRL 296
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 148 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 204
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 205 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 259
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 260 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 319
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 320 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 378
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
>7sd1_D D Leucine-rich repeat protein SHOC-2
Length=585
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 378
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 379 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 433
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 434 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 489
Query 216 CFH 218
H
Sbjct 490 IGH 492
Score = 41.2 bits (95), Expect = 0.053, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 144 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 202
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 203 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 234
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 235 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 287
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 288 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 318
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 371
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 372 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 421
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 422 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 476
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 477 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 530
Score = 39.3 bits (90), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 123 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 180
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 181 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 240
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 241 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 293
Query 207 NQI 209
N++
Sbjct 294 NRL 296
Score = 38.9 bits (89), Expect = 0.28, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 148 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 204
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 205 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 259
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 260 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 319
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 320 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 378
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
>6nih_B B Toll-like receptor 1,Variable lymphocyte receptor B
Length=545
Score = 47.0 bits (110), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 50/185 (27%), Positives = 82/185 (44%), Gaps = 28/185 (15%)
Query 499 PSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFL 558
PS P +L D SNN + + + L +LE L LQ N L L K A + L
Sbjct 344 PSKISPFLHL---DFSNNLLTDTVFENCGHLTELETLILQMNQLKELSKIAEMTTQMKSL 400
Query 559 KGLS-------------------HLHILNLESNGFDEIPVEVFKDLF-ELKIIDLGLNNL 598
+ L L LN+ SN + +F+ L +K++DL N +
Sbjct 401 QQLDISQNSVSYDEKKGDCSWTKSLLSLNMSSNILTDT---IFRCLPPRIKVLDLHSNKI 457
Query 599 NTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFV 658
++P V + +L+ LN+ N + SV +F +L ++ + NP+DC+C I +
Sbjct 458 KSIPKQVVKLE-ALQELNVASNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYLS 515
Query 659 NWINE 663
W+N+
Sbjct 516 RWLNK 520
Score = 39.3 bits (90), Expect = 0.21, Method: Compositional matrix adjust.
Identities = 115/544 (21%), Positives = 222/544 (41%), Gaps = 94/544 (17%)
Query 34 VADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPE 93
+ D S L VP DL T+LN++ N + L ++ S+L L + N I L+
Sbjct 28 LVDRSKNGLIHVPKDLSQKTTILNISQNYISELWTSDILSLSKLRILIISHNRIQYLDIS 87
Query 94 LCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD 153
+ + L+ L+L HN+L ++S NL L L N+ + P K+ ++
Sbjct 88 VFKFNQELEYLDLSHNKLVKISCHP---TVNLKHLDLSFNAFDAL---PICKEFGNMS-Q 140
Query 154 LSHNGLSSTKLGTQVQLE----NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
L GLS+T L L N+ ++LL + K + +
Sbjct 141 LKFLGLSTTHLEKSSVLPIAHLNISKVLLVLGETYGEKEDP----------------EGL 184
Query 210 KEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNT--- 266
++F+ H + F N + L+++ ++ NL LSN + N
Sbjct 185 QDFNTESLHIV------FPTNKEF------HFILDVSVKTVANLELSNIKCVLEDNKCSY 232
Query 267 --TFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEY----FFLEYNNIQHLFSHSLHG 320
+ L TN + +L+ NN+ N SF + QL + ++ +N++ L G
Sbjct 233 FLSILAKLQTNPKLSNLTLNNIETTWN-SFIRILQLVWHTTVWYFSISNVK------LQG 285
Query 321 LFNVRYLNLKRSFTKQSISLASLPKI--DDFSFQWLKCLE---HLNMEDNDIPGIKSNMF 375
+ R + ++ S+ S+ ++ D F F E ++N+++ + G + M
Sbjct 286 QLDFRDFD----YSGTSLKALSIHQVVSDVFGFPQSYIYEIFSNMNIKNFTVSGTR--MV 339
Query 376 TGLINLK-----YLSLSNSFTSLRTLTNETFVSLAH-SPLHILNLTKNKISKIE--SDAF 427
L K +L SN+ LT+ F + H + L L L N++ ++ ++
Sbjct 340 HMLCPSKISPFLHLDFSNNL-----LTDTVFENCGHLTELETLILQMNQLKELSKIAEMT 394
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+ + L+ LD+ N + + + +++ + +S N LT F +P R+ +
Sbjct 395 TQMKSLQQLDISQNSVSYDEKKGDCSWTKSLLSLNMSSNI---LTDTIFRCLPP--RIKV 449
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
+ + S P L L L++++N + ++ D + + L L+ ++W
Sbjct 450 LDLHSNKIKSIPKQVVKLEALQELNVASNQLKSVPDGIFDRLTSLQ----------KIWL 499
Query 548 HANP 551
H NP
Sbjct 500 HTNP 503
>7sd1_A A Leucine-rich repeat protein SHOC-2
Length=585
Score = 47.0 bits (110), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 378
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 379 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 433
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 434 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 489
Query 216 CFH 218
H
Sbjct 490 IGH 492
Score = 41.2 bits (95), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 144 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 202
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 203 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 234
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 235 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 287
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 288 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 318
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 371
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 372 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 421
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 422 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 476
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 477 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 530
Score = 39.3 bits (90), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 123 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 180
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 181 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 240
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 241 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 293
Query 207 NQI 209
N++
Sbjct 294 NRL 296
Score = 38.9 bits (89), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 148 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 204
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 205 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 259
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 260 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 319
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 320 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 378
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
>7tvf_F D Leucine-rich repeat protein SHOC-2
Length=582
Score = 47.0 bits (110), Expect = 9e-04, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 378
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 379 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 433
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 434 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 489
Query 216 CFH 218
H
Sbjct 490 IGH 492
Score = 41.2 bits (95), Expect = 0.054, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 144 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 202
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 203 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 234
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 235 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 287
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 288 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 318
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 319 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 371
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 372 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 421
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 422 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 476
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 477 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 530
Score = 38.9 bits (89), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 123 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 180
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 181 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 240
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 241 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 293
Query 207 NQI 209
N++
Sbjct 294 NRL 296
Score = 38.9 bits (89), Expect = 0.29, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 148 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 204
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 205 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 259
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 260 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 319
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 320 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 378
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 419
>7upi_C C Leucine-rich repeat protein SHOC-2
Length=583
Score = 47.0 bits (110), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 320 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 379
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 380 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 434
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 435 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 490
Query 216 CFH 218
H
Sbjct 491 IGH 493
Score = 41.2 bits (95), Expect = 0.051, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 145 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 203
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 204 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 235
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 236 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 288
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 289 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 319
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 320 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 372
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 373 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 422
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 423 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 477
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 478 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 531
Score = 38.9 bits (89), Expect = 0.26, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 124 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 181
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 182 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 241
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 242 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 294
Query 207 NQI 209
N++
Sbjct 295 NRL 297
Score = 38.1 bits (87), Expect = 0.43, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 149 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 205
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 206 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 260
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 261 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 320
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 321 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 379
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 380 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 420
>7tvg_A D Leucine-rich repeat protein SHOC-2
Length=507
Score = 46.6 bits (109), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 52/183 (28%), Positives = 94/183 (51%), Gaps = 15/183 (8%)
Query 42 LTQVPDDLPTNITVLN---LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
++ +P+ L +++ LN L N + P +++S + SL++ N I+K+ + +
Sbjct 262 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA 321
Query 99 PMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLD---LS 155
+L LN++ N+L+ L F T++ EL+L +N + KI + L++L+ LS
Sbjct 322 KVLSKLNMKDNQLTSLP-LDFGTWTSMVELNLATNQLTKIPED----VSGLVSLEVLILS 376
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPG 215
+N L G L L+EL L NK+++L +E I L+KL L++NQ+ G
Sbjct 377 NNLLKKLPHGLG-NLRKLRELDLEENKLESLPNE---IAYLKDLQKLVLTNNQLTTLPRG 432
Query 216 CFH 218
H
Sbjct 433 IGH 435
Score = 40.4 bits (93), Expect = 0.095, Method: Compositional matrix adjust.
Identities = 124/478 (26%), Positives = 194/478 (41%), Gaps = 127/478 (27%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
C V+ S LT +PD L + +L+L HN+LR +P+ + R LT+L + FN
Sbjct 87 CLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVY-RLDSLTTLYLRFN 145
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNP--F 143
I+ +E ++ NL++L ++S KIK P
Sbjct 146 RITTVEKDI----------------------------KNLSKLSMLSIRENKIKQLPAEI 177
Query 144 VKQKNLITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLK 200
+ NLITLD++HN L ++G Q+ NL L +N++ L D N SSL
Sbjct 178 GELCNLITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLS 230
Query 201 KLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQL 260
+L L N++ AI R LA S +
Sbjct 231 RLGLRYNRLS--------AIPR---------------------SLAKCSALEELNLENNN 261
Query 261 STTSNTTFLG--LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSL 318
+T + L +K +LT+ + V G F+ + L +E+N I +
Sbjct 262 ISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLN---MEHNRINKIP---- 314
Query 319 HGLFN----VRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNM 374
G+F+ + LN+K + L SLP DF W +E LN+ N + I ++
Sbjct 315 FGIFSRAKVLSKLNMKDN------QLTSLPL--DFG-TWTSMVE-LNLATNQLTKIPEDV 364
Query 375 FTGLINLKYLSLSNSF---------------------TSLRTLTNETFVSLAH-SPLHIL 412
+GL++L+ L LSN+ L +L NE +A+ L L
Sbjct 365 -SGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNE----IAYLKDLQKL 419
Query 413 NLTKNKISKIESDAFSWLGHLEVLD-LGLNEIGQELTGQEWRGLENIFEIYLSYNKYL 469
LT N+++ + +GHL L LGL E +E LEN+ E+YL+ N L
Sbjct 420 VLTNNQLTTLPR----GIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNL 473
Score = 38.9 bits (89), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 53/183 (29%), Positives = 86/183 (47%), Gaps = 33/183 (18%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T +T L L N+L+ LPA L +L + N+++ L P+ L L++L+L+HN+
Sbjct 66 TQLTELYLYSNKLQSLPAE-VGCLVNLMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNK 123
Query 111 LSQLSDKTFAF-------------------CTNLTELHLMSNSIQKIKNNP--FVKQKNL 149
L ++ + NL++L ++S KIK P + NL
Sbjct 124 LREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNL 183
Query 150 ITLDLSHNGLS--STKLGTQVQLENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSS 206
ITLD++HN L ++G Q+ NL L +N++ L D N SSL +L L
Sbjct 184 ITLDVAHNQLEHLPKEIGNCTQITNLD---LQHNELLDLP----DTIGNLSSLSRLGLRY 236
Query 207 NQI 209
N++
Sbjct 237 NRL 239
Score = 38.5 bits (88), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 69/281 (25%), Positives = 128/281 (46%), Gaps = 28/281 (10%)
Query 409 LHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKY 468
L L L++N ++ + D+ L L +LDL N++ +E+ +R L+++ +YL +N+
Sbjct 91 LMTLALSENSLTSL-PDSLDNLKKLRMLDLRHNKL-REIPSVVYR-LDSLTTLYLRFNRI 147
Query 469 LQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEG 528
+ ++ + +L +L + + + P+ L NL LD+++N + ++ ++
Sbjct 148 TTVEKD----IKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEI-GN 202
Query 529 LEKLEILDLQHN-------------NLARLWKHANPGGPI-YFLKGLSHLHILNLESNGF 574
++ LDLQHN +L+RL N I L S L LNLE+N
Sbjct 203 CTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNI 262
Query 575 DEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAF 634
+P + L +L + L N P + ++ SLN++ N I + +F A
Sbjct 263 STLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRA- 321
Query 635 RNLTELDMRFN-----PFDCTCESIAWFVNWINETHTNIPE 670
+ L++L+M+ N P D + +N T IPE
Sbjct 322 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPE 362
>4u09_B B LIC12759
Length=409
Score = 46.2 bits (108), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 58/160 (36%), Positives = 86/160 (54%), Gaps = 10/160 (6%)
Query 50 PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHN 109
P ++ L+L+ L+ LP + L LD+G N + L E+ Q L L+ LNL +N
Sbjct 18 PADVRNLDLSFQGLKTLPNK-IGQLKNLQKLDLGGNEPTILSKEIWQ-LKDLQKLNLNNN 75
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV- 168
+L+ L K NL EL L SN + + + KNL L+L +N L T L ++
Sbjct 76 KLTVLP-KEIGQLQNLQELSLHSNELVNLPKE-IGQFKNLQKLNLDNNKL--TVLPKEIG 131
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
QL+NLQEL L +NK+ +L +E I SLK L+L+ N+
Sbjct 132 QLQNLQELSLLSNKLISLPTE---IEQLKSLKNLDLNHNE 168
Score = 38.1 bits (87), Expect = 0.40, Method: Compositional matrix adjust.
Identities = 67/248 (27%), Positives = 101/248 (41%), Gaps = 67/248 (27%)
Query 28 CTVSHEVA--------DCSHLKLTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQL 77
TVS EV D KL +P ++ ++ VL LT NQL LP + L
Sbjct 170 TTVSKEVMLLETLENLDLRSNKLKTIPKEIRQLKSLKVLMLTGNQLTSLPKE-IEQLQNL 228
Query 78 TSLDVG-----------------------FNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
+L++G +N + + E+ Q L LK L+L HN+++ L
Sbjct 229 KTLNLGENRFQIFPVEILELKNLLELNLYYNQLVEFPKEVGQ-LKSLKYLSLYHNQITTL 287
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV-QLENL 173
+ +L ELHL N I T L ++ QL+NL
Sbjct 288 PVEVTQL-PDLQELHLSGNKI--------------------------TILPKEILQLKNL 320
Query 174 QELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
+ L LSNNK+ AL E I L++LEL +NQ+ P + L L L++ +
Sbjct 321 EWLSLSNNKLNALPKE---IGQLKKLQRLELGNNQLTTL-PKEIEQLKNLQRLELDSNPI 376
Query 234 GPSLTEKL 241
P E++
Sbjct 377 SPKEKERI 384
Score = 37.0 bits (84), Expect = 0.94, Method: Compositional matrix adjust.
Identities = 87/346 (25%), Positives = 138/346 (40%), Gaps = 66/346 (19%)
Query 348 DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHS 407
D SFQ LK L N L NL+ L L + ++ L+ E +
Sbjct 25 DLSFQGLKTL--------------PNKIGQLKNLQKLDLGGNEPTI--LSKEIW---QLK 65
Query 408 PLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNK 467
L LNL NK++ + + L +L+ L L NE+ +E +N+ ++ L NK
Sbjct 66 DLQKLNLNNNKLTVLPKE-IGQLQNLQELSLHSNELVN--LPKEIGQFKNLQKLNLDNNK 122
Query 468 YLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLE 527
L + + LQ L + + S P+ + L++L LDL++N ++ +++
Sbjct 123 LTVLPKE----IGQLQNLQELSLLSNKLISLPTEIEQLKSLKNLDLNHNEFTTVSKEVM- 177
Query 528 GLEKLEILDLQHNNLARLWKHANPGGPIYFL--------------KGLSHLHILNLESNG 573
LE LE LDL+ N L + K + L + L +L LNL N
Sbjct 178 LLETLENLDLRSNKLKTIPKEIRQLKSLKVLMLTGNQLTSLPKEIEQLQNLKTLNLGENR 237
Query 574 FDEIPVEV------------FKDLFE----------LKIIDLGLNNLNTLPASVFNNQVS 611
F PVE+ + L E LK + L N + TLP V
Sbjct 238 FQIFPVEILELKNLLELNLYYNQLVEFPKEVGQLKSLKYLSLYHNQITTLPVEV-TQLPD 296
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWF 657
L+ L+L N IT + K++ +NL L + N + + I
Sbjct 297 LQELHLSGNKITILPKEIL--QLKNLEWLSLSNNKLNALPKEIGQL 340
Score = 35.4 bits (80), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 109/403 (27%), Positives = 175/403 (43%), Gaps = 61/403 (15%)
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW-LPQLEYFFLE 306
+RNL LS L T N + NL LDL N ++ + W L L+ L
Sbjct 19 ADVRNLDLSFQGLKTLPNKIG---QLKNLQKLDLGGNEPTILSKE--IWQLKDLQKLNLN 73
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK-IDDFSFQWLKCLEHLNMEDN 365
N + + + L N++ L+L S L +LPK I F K L+ LN+++N
Sbjct 74 NNKL-TVLPKEIGQLQNLQELSL------HSNELVNLPKEIGQF-----KNLQKLNLDNN 121
Query 366 DIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
+ + L NL+ LSL SN SL T E SL + L+L N+ + +
Sbjct 122 KL-TVLPKEIGQLQNLQELSLLSNKLISLPTEI-EQLKSLKN-----LDLNHNEFTTVSK 174
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYN---------------KYL 469
+ L LE LDL N++ + +E R L+++ + L+ N K L
Sbjct 175 EVM-LLETLENLDLRSNKL--KTIPKEIRQLKSLKVLMLTGNQLTSLPKEIEQLQNLKTL 231
Query 470 QLTRNSFALVP----SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
L N F + P L+ L+ + + P L++L L L +N I + ++
Sbjct 232 NLGENRFQIFPVEILELKNLLELNLYYNQLVEFPKEVGQLKSLKYLSLYHNQITTLPVEV 291
Query 526 LEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDL 585
+ L L+ L L N + L K + L +L L+L +N + +P E+ + L
Sbjct 292 TQ-LPDLQELHLSGNKITILPKE---------ILQLKNLEWLSLSNNKLNALPKEIGQ-L 340
Query 586 FELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
+L+ ++LG N L TLP + +L+ L L N I+ EK+
Sbjct 341 KKLQRLELGNNQLTTLPKEI-EQLKNLQRLELDSNPISPKEKE 382
>8ben_D D Volume-regulated anion channel subunit LRRC8C
Length=412
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 59/200 (30%), Positives = 100/200 (50%), Gaps = 18/200 (9%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC-QKLPMLKVLNLQHN 109
TN+T L L H L R+P A F+ S L LD+ N + +E + Q L L VL L +N
Sbjct 197 TNLTELELVHCDLERIPHAVFSLLS-LQELDLKENNLKSIEEIVSFQHLRKLTVLKLWYN 255
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS--STKLGTQ 167
++ + + T+L L N ++ + ++ F+ K + LDLS+N + ++G
Sbjct 256 SIAYIPEHIKKL-TSLERLFFSHNKVEVLPSHLFLCNK-IRYLDLSYNDIRFIPPEIGV- 312
Query 168 VQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLF 227
L++LQ ++ NK+++L E ++ LK L++ N + SP IG L LF
Sbjct 313 --LQSLQYFSITCNKVESLPDE---LYFCKKLKTLKIGKNSLSVLSP----KIGNL--LF 361
Query 228 LNNVQLGPSLTEKLCLELAN 247
L+ + + + E L EL +
Sbjct 362 LSYLDIKGNHFEVLPPELGD 381
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 84/315 (27%), Positives = 146/315 (46%), Gaps = 40/315 (13%)
Query 345 KIDDFSFQWLK-CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFT----------SL 393
KI + +LK L+ L+++ +D+ + M+ GL NL+ L L S + SL
Sbjct 88 KIHSAALSFLKENLKVLSVKFDDMRELPPWMY-GLRNLEELYLVGSLSHXXXXXXXLESL 146
Query 394 RTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWR 453
R L + +S+ K+ +SKI HL+ + + N+ + + +
Sbjct 147 RDLKSLKILSI-----------KSNVSKIPQAVVDVSSHLQKMCVH-NDGTKLVMLNNLK 194
Query 454 GLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDL 513
+ N+ E+ L + ++ F+L+ SLQ L L+ LK+++ S FQ LR LT+L L
Sbjct 195 KMTNLTELELVHCDLERIPHAVFSLL-SLQELDLKENNLKSIEEIVS-FQHLRKLTVLKL 252
Query 514 SNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNG 573
N+IA I + ++ L LE L HN + L H I + L+L N
Sbjct 253 WYNSIAYIPEH-IKKLTSLERLFFSHNKVEVLPSHLFLCNKIRY---------LDLSYND 302
Query 574 FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPA 633
IP E+ L L+ + N + +LP ++ + LK+L + KN ++ + K+
Sbjct 303 IRFIPPEI-GVLQSLQYFSITCNKVESLPDELYFCK-KLKTLKIGKNSLSVLSPKIGNLL 360
Query 634 FRNLTELDMRFNPFD 648
F L+ LD++ N F+
Sbjct 361 F--LSYLDIKGNHFE 373
>4u09_A A LIC12759
Length=409
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 58/160 (36%), Positives = 86/160 (54%), Gaps = 10/160 (6%)
Query 50 PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHN 109
P ++ L+L+ L+ LP + L LD+G N + L E+ Q L L+ LNL +N
Sbjct 18 PADVRNLDLSFQGLKTLPNK-IGQLKNLQKLDLGGNEPTILSKEIWQ-LKDLQKLNLNNN 75
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV- 168
+L+ L K NL EL L SN + + + KNL L+L +N L T L ++
Sbjct 76 KLTVLP-KEIGQLQNLQELSLHSNELVNLPKE-IGQFKNLQKLNLDNNKL--TVLPKEIG 131
Query 169 QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQ 208
QL+NLQEL L +NK+ +L +E I SLK L+L+ N+
Sbjct 132 QLQNLQELSLLSNKLISLPTE---IEQLKSLKNLDLNHNE 168
Score = 37.7 bits (86), Expect = 0.52, Method: Compositional matrix adjust.
Identities = 67/248 (27%), Positives = 101/248 (41%), Gaps = 67/248 (27%)
Query 28 CTVSHEVA--------DCSHLKLTQVPDDLP--TNITVLNLTHNQLRRLPAANFTRYSQL 77
TVS EV D KL +P ++ ++ VL LT NQL LP + L
Sbjct 170 TTVSKEVMLLETLENLDLRSNKLKTIPKEIRQLKSLKVLMLTGNQLTSLPKE-IEQLQNL 228
Query 78 TSLDVG-----------------------FNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
+L++G +N + + E+ Q L LK L+L HN+++ L
Sbjct 229 KTLNLGENRFQIFPVEILELKNLLELNLYYNQLVEFPKEVGQ-LKSLKYLSLYHNQITTL 287
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV-QLENL 173
+ +L ELHL N I T L ++ QL+NL
Sbjct 288 PVEVTQL-PDLQELHLSGNKI--------------------------TILPKEILQLKNL 320
Query 174 QELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQL 233
+ L LSNNK+ AL E I L++LEL +NQ+ P + L L L++ +
Sbjct 321 EWLSLSNNKLNALPKE---IGQLKKLQRLELGNNQLTTL-PKEIEQLKNLQRLELDSNPI 376
Query 234 GPSLTEKL 241
P E++
Sbjct 377 SPKEKERI 384
Score = 36.6 bits (83), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 87/346 (25%), Positives = 138/346 (40%), Gaps = 66/346 (19%)
Query 348 DFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHS 407
D SFQ LK L N L NL+ L L + ++ L+ E +
Sbjct 25 DLSFQGLKTL--------------PNKIGQLKNLQKLDLGGNEPTI--LSKEIW---QLK 65
Query 408 PLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNK 467
L LNL NK++ + + L +L+ L L NE+ +E +N+ ++ L NK
Sbjct 66 DLQKLNLNNNKLTVLPKE-IGQLQNLQELSLHSNELVN--LPKEIGQFKNLQKLNLDNNK 122
Query 468 YLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLE 527
L + + LQ L + + S P+ + L++L LDL++N ++ +++
Sbjct 123 LTVLPKE----IGQLQNLQELSLLSNKLISLPTEIEQLKSLKNLDLNHNEFTTVSKEVM- 177
Query 528 GLEKLEILDLQHNNLARLWKHANPGGPIYFL--------------KGLSHLHILNLESNG 573
LE LE LDL+ N L + K + L + L +L LNL N
Sbjct 178 LLETLENLDLRSNKLKTIPKEIRQLKSLKVLMLTGNQLTSLPKEIEQLQNLKTLNLGENR 237
Query 574 FDEIPVEV------------FKDLFE----------LKIIDLGLNNLNTLPASVFNNQVS 611
F PVE+ + L E LK + L N + TLP V
Sbjct 238 FQIFPVEILELKNLLELNLYYNQLVEFPKEVGQLKSLKYLSLYHNQITTLPVEV-TQLPD 296
Query 612 LKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWF 657
L+ L+L N IT + K++ +NL L + N + + I
Sbjct 297 LQELHLSGNKITILPKEIL--QLKNLEWLSLSNNKLNALPKEIGQL 340
Score = 34.7 bits (78), Expect = 5.2, Method: Compositional matrix adjust.
Identities = 111/407 (27%), Positives = 177/407 (43%), Gaps = 69/407 (17%)
Query 248 TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAW-LPQLEYFFLE 306
+RNL LS L T N +G + NL LDL N ++ + W L L+ L
Sbjct 19 ADVRNLDLSFQGLKTLPNK--IG-QLKNLQKLDLGGNEPTILSKE--IWQLKDLQKLNLN 73
Query 307 YNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPK-IDDFSFQWLKCLEHLNMEDN 365
N + + + L N++ L+L S L +LPK I F K L+ LN+++N
Sbjct 74 NNKL-TVLPKEIGQLQNLQELSL------HSNELVNLPKEIGQF-----KNLQKLNLDNN 121
Query 366 DIPGIKSNMFTGLINLKYLSL-SNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIES 424
+ + L NL+ LSL SN SL T E SL + L+L N+ + +
Sbjct 122 KL-TVLPKEIGQLQNLQELSLLSNKLISLPTEI-EQLKSLKN-----LDLNHNEFTTVSK 174
Query 425 DAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYN---------------KYL 469
+ L LE LDL N++ + +E R L+++ + L+ N K L
Sbjct 175 EVM-LLETLENLDLRSNKL--KTIPKEIRQLKSLKVLMLTGNQLTSLPKEIEQLQNLKTL 231
Query 470 QLTRNSFALVP----SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDM 525
L N F + P L+ L+ + + P L++L L L +N I +
Sbjct 232 NLGENRFQIFPVEILELKNLLELNLYYNQLVEFPKEVGQLKSLKYLSLYHNQITTL---- 287
Query 526 LEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG----LSHLHILNLESNGFDEIPVEV 581
+E ++ DLQ +L+ G I L L +L L+L +N + +P E+
Sbjct 288 --PVEVTQLPDLQELHLS--------GNKITILPKEILQLKNLEWLSLSNNKLNALPKEI 337
Query 582 FKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKK 628
+ L +L+ ++LG N L TLP + +L+ L L N I+ EK+
Sbjct 338 GQ-LKKLQRLELGNNQLTTLPKEI-EQLKNLQRLELDSNPISPKEKE 382
>5b0n_A A E3 ubiquitin-protein ligase ipaH9.8
Length=224
Score = 44.7 bits (104), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 37/105 (35%), Positives = 53/105 (50%), Gaps = 11/105 (10%)
Query 39 HLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
L L+ +PD+LP IT+LN+++NQL LP T L L N +S+L P L
Sbjct 45 RLNLSSLPDNLPAQITLLNVSYNQLTNLPELPVT----LKKLYSASNKLSEL-PVLP--- 96
Query 99 PMLKVLNLQHNE---LSQLSDKTFAFCTNLTELHLMSNSIQKIKN 140
P L+ L +QHNE L L D + E+ + + Q +KN
Sbjct 97 PALESLQVQHNELENLPALPDSLLTMNISYNEIVSLPSLPQALKN 141
>8i2g_E R Follicle-stimulating hormone receptor
Length=678
Score = 45.8 bits (107), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 70/274 (26%), Positives = 121/274 (44%), Gaps = 38/274 (14%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYL-SYNKYLQ 470
L K+ I+ AFS G LE +++ N++ + + + L + EI + N L
Sbjct 34 LRFVLTKLRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLY 93
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN-NIANINDDMLEGL 529
+ +F +P+LQ L++ +K++ L+ + +LD+ +N NI I + GL
Sbjct 94 INPEAFQNLPNLQYLLISNTGIKHLPDV-HKIHSLQKV-LLDIQDNINIHTIERNSFVGL 151
Query 530 E-KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL-ESNGFDEIPVEVFKDLFE 587
+ IL L N + + A G + L LNL ++N +E+P +VF
Sbjct 152 SFESVILWLNKNGIQEIHNCAFNG---------TQLDELNLSDNNNLEELPNDVFHGASG 202
Query 588 LKIIDLGLNNLNTLPASVFNNQVSLKS---LNLQKNLITSVEKKVFGPAFRNLTELDMRF 644
I+D+ +++LP+ N L++ NL+K + ++EK V L E + +
Sbjct 203 PVILDISRTRIHSLPSYGLENLKKLRARSTYNLKK--LPTLEKLV------ALMEASLTY 254
Query 645 NPFDCTCESIAWFVNWINETHTNIPELSSHYLCN 678
P C F NW I EL H +CN
Sbjct 255 -PIHCCA-----FANW----RRQISEL--HPICN 276
Score = 43.1 bits (100), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 47/197 (24%), Positives = 90/197 (46%), Gaps = 8/197 (4%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C S+ V C K+T++P DLP N L +LR + F+ + L +++ N +
Sbjct 6 CHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEISQNDV 65
Query 88 SK-LEPELCQKLPMLKVLNLQH-NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ +E ++ LP L + ++ N L ++ + F NL L + + I+ + + +
Sbjct 66 LEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPNLQYLLISNTGIKHLPDVHKIH 125
Query 146 QKNLITLDLSHN-GLSSTKLGTQVQLENLQELL-LSNNKIQALKSEELDIFANSSLKKLE 203
+ LD+ N + + + + V L +L L+ N IQ + + F + L +L
Sbjct 126 SLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKNGIQEIHNCA---FNGTQLDELN 182
Query 204 LS-SNQIKEFSPGCFHA 219
LS +N ++E FH
Sbjct 183 LSDNNNLEELPNDVFHG 199
>5b0t_A A E3 ubiquitin-protein ligase ipaH9.8
Length=224
Score = 44.3 bits (103), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 37/105 (35%), Positives = 53/105 (50%), Gaps = 11/105 (10%)
Query 39 HLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
L L+ +PD+LP IT+LN+++NQL LP T L L N +S+L P L
Sbjct 45 RLNLSSLPDNLPAQITLLNVSYNQLTNLPELPVT----LKKLYSASNKLSEL-PVLP--- 96
Query 99 PMLKVLNLQHNE---LSQLSDKTFAFCTNLTELHLMSNSIQKIKN 140
P L+ L +QHNE L L D + E+ + + Q +KN
Sbjct 97 PALESLQVQHNELENLPALPDSLLTMNISYNEIVSLPSLPQALKN 141
>6loj_A A Invasion plasmid antigen
Length=226
Score = 44.3 bits (103), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 37/105 (35%), Positives = 53/105 (50%), Gaps = 11/105 (10%)
Query 39 HLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
L L+ +PD+LP IT+LN+++NQL LP T L L N +S+L P L
Sbjct 47 RLNLSSLPDNLPAQITLLNVSYNQLTNLPELPVT----LKKLYSASNKLSEL-PVLP--- 98
Query 99 PMLKVLNLQHNE---LSQLSDKTFAFCTNLTELHLMSNSIQKIKN 140
P L+ L +QHNE L L D + E+ + + Q +KN
Sbjct 99 PALESLQVQHNELENLPALPDSLLTMNISYNEIVSLPSLPQALKN 143
>5b0n_B B E3 ubiquitin-protein ligase ipaH9.8
Length=224
Score = 44.3 bits (103), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 32/76 (42%), Positives = 43/76 (57%), Gaps = 8/76 (11%)
Query 39 HLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
L L+ +PD+LP IT+LN+++NQL LP T L L N +S+L P L
Sbjct 45 RLNLSSLPDNLPAQITLLNVSYNQLTNLPELPVT----LKKLYSASNKLSEL-PVLP--- 96
Query 99 PMLKVLNLQHNELSQL 114
P L+ L +QHNEL L
Sbjct 97 PALESLQVQHNELENL 112
>6lol_A A E3 ubiquitin-protein ligase ipaH9.8
Length=526
Score = 45.4 bits (106), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 32/76 (42%), Positives = 43/76 (57%), Gaps = 8/76 (11%)
Query 39 HLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
L L+ +PD+LP IT+LN+++NQL LP T L L N +S+L P L
Sbjct 46 RLNLSSLPDNLPAQITLLNVSYNQLTNLPELPVT----LKKLYSASNKLSEL-PVLP--- 97
Query 99 PMLKVLNLQHNELSQL 114
P L+ L +QHNEL L
Sbjct 98 PALESLQVQHNELENL 113
>6k2d_B B E3 ubiquitin-protein ligase ipaH9.8
Length=236
Score = 44.3 bits (103), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 37/105 (35%), Positives = 53/105 (50%), Gaps = 11/105 (10%)
Query 39 HLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
L L+ +PD+LP IT+LN+++NQL LP T L L N +S+L P L
Sbjct 49 RLNLSSLPDNLPAQITLLNVSYNQLTNLPELPVT----LKKLYSASNKLSEL-PVLP--- 100
Query 99 PMLKVLNLQHNE---LSQLSDKTFAFCTNLTELHLMSNSIQKIKN 140
P L+ L +QHNE L L D + E+ + + Q +KN
Sbjct 101 PALESLQVQHNELENLPALPDSLLTMNISYNEIVSLPSLPQALKN 145
>6zxg_JA k Leucine-rich repeat-containing protein 47
Length=583
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 55/194 (28%), Positives = 77/194 (40%), Gaps = 44/194 (23%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA------NINDDMLEGLEKL 532
+P L L+LRR AL SP PL L +LDLS N + + GL +L
Sbjct 74 LPQLHSLVLRRNAL-GPGLSPE-LGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQL 131
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKD-------- 584
+ L+L N L L P + L LNL N D P E+F+
Sbjct 132 QSLNLSGNRLREL--------PADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSE 183
Query 585 -----------------LFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS--V 625
L LK +DL N L+ +PA + + LK +N + N + +
Sbjct 184 LAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCP-KLKEINFRGNKLRDKRL 242
Query 626 EKKVFGPAFRNLTE 639
EK V G R++ E
Sbjct 243 EKMVSGCQTRSILE 256
Score = 37.7 bits (86), Expect = 0.63, Method: Compositional matrix adjust.
Identities = 35/114 (31%), Positives = 49/114 (43%), Gaps = 8/114 (7%)
Query 498 SPSP--FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL--WKHANPGG 553
+P P Q L L L L N + L L L +LDL N L L + P
Sbjct 65 APGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAE 124
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
P GL L LNL N E+P ++ + L+ ++L N L++ PA +F
Sbjct 125 P----PGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFR 174
Score = 36.6 bits (83), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 71/158 (45%), Gaps = 14/158 (9%)
Query 65 RLPAANFTR-YSQLTSLDVGFNTISK-LEPELCQKLPMLKVLNLQHNELSQL------SD 116
R P + QL SL + N + L PEL LP L+VL+L N L L
Sbjct 64 RAPGPGLAQGLPQLHSLVLRRNALGPGLSPEL-GPLPALRVLDLSGNALEALPPGQGLGP 122
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS--TKLGTQVQLENLQ 174
L L+L N ++++ + L +L+L+ N L S +L L L
Sbjct 123 AEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLS 182
Query 175 ELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
EL ++N ++ L DI +SLK L+LS+NQ+ E
Sbjct 183 ELAAADNCLRELSP---DIAHLASLKTLDLSNNQLSEI 217
Score = 36.6 bits (83), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 58/204 (28%), Positives = 81/204 (40%), Gaps = 39/204 (19%)
Query 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
+ +FT L L YL +S SLR L LH L L +N + S
Sbjct 42 LPPRLFT-LPLLHYLEVSGC-GSLRAPGPGLAQGLPQ--LHSLVLRRNALGPGLSPELGP 97
Query 430 LGHLEVLDLGLNEI-----GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
L L VLDL N + GQ L E GL + + LS N+ +L + P LQ
Sbjct 98 LPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQS 157
Query 485 LMLRRVALKNVDSSPSP-FQP-------------------------LRNLTILDLSNNNI 518
L L L DS P+ F+P L +L LDLSNN +
Sbjct 158 LNLTGNCL---DSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQL 214
Query 519 ANINDDMLEGLEKLEILDLQHNNL 542
+ I ++ + KL+ ++ + N L
Sbjct 215 SEIPAELAD-CPKLKEINFRGNKL 237
Score = 35.0 bits (79), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 38/128 (30%), Positives = 56/128 (44%), Gaps = 25/128 (20%)
Query 525 MLEGLEKLEILDLQHNNLARLWKHANPG-----GPIYFLKGLSHLHILNLESNGFDEIPV 579
+ +GL +L L L+ N L PG GP L L +L+L N + +P
Sbjct 70 LAQGLPQLHSLVLRRNALG-------PGLSPELGP------LPALRVLDLSGNALEALPP 116
Query 580 ------EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP- 632
L +L+ ++L N L LPA + L+SLNL N + S ++F P
Sbjct 117 GQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPG 176
Query 633 AFRNLTEL 640
A L+EL
Sbjct 177 ALPLLSEL 184
>6zxe_JA k Leucine-rich repeat-containing protein 47
Length=583
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 55/194 (28%), Positives = 77/194 (40%), Gaps = 44/194 (23%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA------NINDDMLEGLEKL 532
+P L L+LRR AL SP PL L +LDLS N + + GL +L
Sbjct 74 LPQLHSLVLRRNAL-GPGLSPE-LGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQL 131
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKD-------- 584
+ L+L N L L P + L LNL N D P E+F+
Sbjct 132 QSLNLSGNRLREL--------PADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSE 183
Query 585 -----------------LFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS--V 625
L LK +DL N L+ +PA + + LK +N + N + +
Sbjct 184 LAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCP-KLKEINFRGNKLRDKRL 242
Query 626 EKKVFGPAFRNLTE 639
EK V G R++ E
Sbjct 243 EKMVSGCQTRSILE 256
Score = 37.7 bits (86), Expect = 0.63, Method: Compositional matrix adjust.
Identities = 35/114 (31%), Positives = 49/114 (43%), Gaps = 8/114 (7%)
Query 498 SPSP--FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL--WKHANPGG 553
+P P Q L L L L N + L L L +LDL N L L + P
Sbjct 65 APGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAE 124
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
P GL L LNL N E+P ++ + L+ ++L N L++ PA +F
Sbjct 125 P----PGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFR 174
Score = 36.6 bits (83), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 71/158 (45%), Gaps = 14/158 (9%)
Query 65 RLPAANFTR-YSQLTSLDVGFNTISK-LEPELCQKLPMLKVLNLQHNELSQL------SD 116
R P + QL SL + N + L PEL LP L+VL+L N L L
Sbjct 64 RAPGPGLAQGLPQLHSLVLRRNALGPGLSPEL-GPLPALRVLDLSGNALEALPPGQGLGP 122
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS--TKLGTQVQLENLQ 174
L L+L N ++++ + L +L+L+ N L S +L L L
Sbjct 123 AEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLS 182
Query 175 ELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
EL ++N ++ L DI +SLK L+LS+NQ+ E
Sbjct 183 ELAAADNCLRELSP---DIAHLASLKTLDLSNNQLSEI 217
Score = 36.6 bits (83), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 58/204 (28%), Positives = 81/204 (40%), Gaps = 39/204 (19%)
Query 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
+ +FT L L YL +S SLR L LH L L +N + S
Sbjct 42 LPPRLFT-LPLLHYLEVSGC-GSLRAPGPGLAQGLPQ--LHSLVLRRNALGPGLSPELGP 97
Query 430 LGHLEVLDLGLNEI-----GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
L L VLDL N + GQ L E GL + + LS N+ +L + P LQ
Sbjct 98 LPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQS 157
Query 485 LMLRRVALKNVDSSPSP-FQP-------------------------LRNLTILDLSNNNI 518
L L L DS P+ F+P L +L LDLSNN +
Sbjct 158 LNLTGNCL---DSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQL 214
Query 519 ANINDDMLEGLEKLEILDLQHNNL 542
+ I ++ + KL+ ++ + N L
Sbjct 215 SEIPAELAD-CPKLKEINFRGNKL 237
Score = 35.0 bits (79), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 38/128 (30%), Positives = 56/128 (44%), Gaps = 25/128 (20%)
Query 525 MLEGLEKLEILDLQHNNLARLWKHANPG-----GPIYFLKGLSHLHILNLESNGFDEIPV 579
+ +GL +L L L+ N L PG GP L L +L+L N + +P
Sbjct 70 LAQGLPQLHSLVLRRNALG-------PGLSPELGP------LPALRVLDLSGNALEALPP 116
Query 580 ------EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP- 632
L +L+ ++L N L LPA + L+SLNL N + S ++F P
Sbjct 117 GQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPG 176
Query 633 AFRNLTEL 640
A L+EL
Sbjct 177 ALPLLSEL 184
>6zxd_KA k Leucine-rich repeat-containing protein 47
Length=583
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 55/194 (28%), Positives = 77/194 (40%), Gaps = 44/194 (23%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA------NINDDMLEGLEKL 532
+P L L+LRR AL SP PL L +LDLS N + + GL +L
Sbjct 74 LPQLHSLVLRRNAL-GPGLSPE-LGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQL 131
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKD-------- 584
+ L+L N L L P + L LNL N D P E+F+
Sbjct 132 QSLNLSGNRLREL--------PADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSE 183
Query 585 -----------------LFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS--V 625
L LK +DL N L+ +PA + + LK +N + N + +
Sbjct 184 LAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCP-KLKEINFRGNKLRDKRL 242
Query 626 EKKVFGPAFRNLTE 639
EK V G R++ E
Sbjct 243 EKMVSGCQTRSILE 256
Score = 37.7 bits (86), Expect = 0.63, Method: Compositional matrix adjust.
Identities = 35/114 (31%), Positives = 49/114 (43%), Gaps = 8/114 (7%)
Query 498 SPSP--FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL--WKHANPGG 553
+P P Q L L L L N + L L L +LDL N L L + P
Sbjct 65 APGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAE 124
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
P GL L LNL N E+P ++ + L+ ++L N L++ PA +F
Sbjct 125 P----PGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFR 174
Score = 36.6 bits (83), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 71/158 (45%), Gaps = 14/158 (9%)
Query 65 RLPAANFTR-YSQLTSLDVGFNTISK-LEPELCQKLPMLKVLNLQHNELSQL------SD 116
R P + QL SL + N + L PEL LP L+VL+L N L L
Sbjct 64 RAPGPGLAQGLPQLHSLVLRRNALGPGLSPEL-GPLPALRVLDLSGNALEALPPGQGLGP 122
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS--TKLGTQVQLENLQ 174
L L+L N ++++ + L +L+L+ N L S +L L L
Sbjct 123 AEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLS 182
Query 175 ELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
EL ++N ++ L DI +SLK L+LS+NQ+ E
Sbjct 183 ELAAADNCLRELSP---DIAHLASLKTLDLSNNQLSEI 217
Score = 36.6 bits (83), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 58/204 (28%), Positives = 81/204 (40%), Gaps = 39/204 (19%)
Query 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
+ +FT L L YL +S SLR L LH L L +N + S
Sbjct 42 LPPRLFT-LPLLHYLEVSGC-GSLRAPGPGLAQGLPQ--LHSLVLRRNALGPGLSPELGP 97
Query 430 LGHLEVLDLGLNEI-----GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
L L VLDL N + GQ L E GL + + LS N+ +L + P LQ
Sbjct 98 LPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQS 157
Query 485 LMLRRVALKNVDSSPSP-FQP-------------------------LRNLTILDLSNNNI 518
L L L DS P+ F+P L +L LDLSNN +
Sbjct 158 LNLTGNCL---DSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQL 214
Query 519 ANINDDMLEGLEKLEILDLQHNNL 542
+ I ++ + KL+ ++ + N L
Sbjct 215 SEIPAELAD-CPKLKEINFRGNKL 237
Score = 35.0 bits (79), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 38/128 (30%), Positives = 56/128 (44%), Gaps = 25/128 (20%)
Query 525 MLEGLEKLEILDLQHNNLARLWKHANPG-----GPIYFLKGLSHLHILNLESNGFDEIPV 579
+ +GL +L L L+ N L PG GP L L +L+L N + +P
Sbjct 70 LAQGLPQLHSLVLRRNALG-------PGLSPELGP------LPALRVLDLSGNALEALPP 116
Query 580 ------EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP- 632
L +L+ ++L N L LPA + L+SLNL N + S ++F P
Sbjct 117 GQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPG 176
Query 633 AFRNLTEL 640
A L+EL
Sbjct 177 ALPLLSEL 184
>6zxf_KA k Leucine-rich repeat-containing protein 47
Length=583
Score = 45.1 bits (105), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 55/194 (28%), Positives = 77/194 (40%), Gaps = 44/194 (23%)
Query 479 VPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA------NINDDMLEGLEKL 532
+P L L+LRR AL SP PL L +LDLS N + + GL +L
Sbjct 74 LPQLHSLVLRRNAL-GPGLSPE-LGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQL 131
Query 533 EILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKD-------- 584
+ L+L N L L P + L LNL N D P E+F+
Sbjct 132 QSLNLSGNRLREL--------PADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSE 183
Query 585 -----------------LFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITS--V 625
L LK +DL N L+ +PA + + LK +N + N + +
Sbjct 184 LAAADNCLRELSPDIAHLASLKTLDLSNNQLSEIPAELADCP-KLKEINFRGNKLRDKRL 242
Query 626 EKKVFGPAFRNLTE 639
EK V G R++ E
Sbjct 243 EKMVSGCQTRSILE 256
Score = 37.7 bits (86), Expect = 0.63, Method: Compositional matrix adjust.
Identities = 35/114 (31%), Positives = 49/114 (43%), Gaps = 8/114 (7%)
Query 498 SPSP--FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARL--WKHANPGG 553
+P P Q L L L L N + L L L +LDL N L L + P
Sbjct 65 APGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAE 124
Query 554 PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFN 607
P GL L LNL N E+P ++ + L+ ++L N L++ PA +F
Sbjct 125 P----PGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFR 174
Score = 36.6 bits (83), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 48/158 (30%), Positives = 71/158 (45%), Gaps = 14/158 (9%)
Query 65 RLPAANFTR-YSQLTSLDVGFNTISK-LEPELCQKLPMLKVLNLQHNELSQL------SD 116
R P + QL SL + N + L PEL LP L+VL+L N L L
Sbjct 64 RAPGPGLAQGLPQLHSLVLRRNALGPGLSPEL-GPLPALRVLDLSGNALEALPPGQGLGP 122
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS--TKLGTQVQLENLQ 174
L L+L N ++++ + L +L+L+ N L S +L L L
Sbjct 123 AEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLS 182
Query 175 ELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEF 212
EL ++N ++ L DI +SLK L+LS+NQ+ E
Sbjct 183 ELAAADNCLRELSP---DIAHLASLKTLDLSNNQLSEI 217
Score = 36.6 bits (83), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 58/204 (28%), Positives = 81/204 (40%), Gaps = 39/204 (19%)
Query 370 IKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSW 429
+ +FT L L YL +S SLR L LH L L +N + S
Sbjct 42 LPPRLFT-LPLLHYLEVSGC-GSLRAPGPGLAQGLPQ--LHSLVLRRNALGPGLSPELGP 97
Query 430 LGHLEVLDLGLNEI-----GQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQR 484
L L VLDL N + GQ L E GL + + LS N+ +L + P LQ
Sbjct 98 LPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQS 157
Query 485 LMLRRVALKNVDSSPSP-FQP-------------------------LRNLTILDLSNNNI 518
L L L DS P+ F+P L +L LDLSNN +
Sbjct 158 LNLTGNCL---DSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSNNQL 214
Query 519 ANINDDMLEGLEKLEILDLQHNNL 542
+ I ++ + KL+ ++ + N L
Sbjct 215 SEIPAELAD-CPKLKEINFRGNKL 237
Score = 35.0 bits (79), Expect = 4.0, Method: Compositional matrix adjust.
Identities = 38/128 (30%), Positives = 56/128 (44%), Gaps = 25/128 (20%)
Query 525 MLEGLEKLEILDLQHNNLARLWKHANPG-----GPIYFLKGLSHLHILNLESNGFDEIPV 579
+ +GL +L L L+ N L PG GP L L +L+L N + +P
Sbjct 70 LAQGLPQLHSLVLRRNALG-------PGLSPELGP------LPALRVLDLSGNALEALPP 116
Query 580 ------EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGP- 632
L +L+ ++L N L LPA + L+SLNL N + S ++F P
Sbjct 117 GQGLGPAEPPGLPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPG 176
Query 633 AFRNLTEL 640
A L+EL
Sbjct 177 ALPLLSEL 184
>4ay9_H Y FOLLICLE-STIMULATING HORMONE RECEPTOR
Length=354
Score = 44.7 bits (104), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 69/268 (26%), Positives = 120/268 (45%), Gaps = 38/268 (14%)
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS-YNKYLQLTRNSF 476
K+ I+ AFS G LE +++ N++ + + + L + EI + N L + +F
Sbjct 41 KLRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAF 100
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN-NIANINDDMLEGLE-KLEI 534
+P+LQ L++ +K++ L+ + +LD+ +N NI I + GL + I
Sbjct 101 QNLPNLQYLLISNTGIKHLPDV-HKIHSLQKV-LLDIQDNINIHTIERNSFVGLSFESVI 158
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL-ESNGFDEIPVEVFKDLFELKIIDL 593
L L N + + A G + L LNL ++N +E+P +VF I+D+
Sbjct 159 LWLNKNGIQEIHNSAFNG---------TQLDELNLSDNNNLEELPNDVFHGASGPVILDI 209
Query 594 GLNNLNTLPASVFNNQVSLKS---LNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
+++LP+ N L++ NL+K + ++EK V L E + + P C
Sbjct 210 SRTRIHSLPSYGLENLKKLRARSTYNLKK--LPTLEKLVA------LMEASLTY-PSHC- 259
Query 651 CESIAWFVNWINETHTNIPELSSHYLCN 678
F NW I EL H +CN
Sbjct 260 ----CAFANW----RRQISEL--HPICN 277
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/197 (24%), Positives = 90/197 (46%), Gaps = 8/197 (4%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C S+ V C K+T++P DLP N L +LR + F+ + L +++ N +
Sbjct 7 CHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEISQNDV 66
Query 88 SK-LEPELCQKLPMLKVLNLQH-NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ +E ++ LP L + ++ N L ++ + F NL L + + I+ + + +
Sbjct 67 LEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPNLQYLLISNTGIKHLPDVHKIH 126
Query 146 QKNLITLDLSHN-GLSSTKLGTQVQLENLQELL-LSNNKIQALKSEELDIFANSSLKKLE 203
+ LD+ N + + + + V L +L L+ N IQ + + F + L +L
Sbjct 127 SLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKNGIQEIHNSA---FNGTQLDELN 183
Query 204 LS-SNQIKEFSPGCFHA 219
LS +N ++E FH
Sbjct 184 LSDNNNLEELPNDVFHG 200
>4ay9_I Z FOLLICLE-STIMULATING HORMONE RECEPTOR
Length=354
Score = 44.7 bits (104), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 69/268 (26%), Positives = 120/268 (45%), Gaps = 38/268 (14%)
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS-YNKYLQLTRNSF 476
K+ I+ AFS G LE +++ N++ + + + L + EI + N L + +F
Sbjct 41 KLRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAF 100
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN-NIANINDDMLEGLE-KLEI 534
+P+LQ L++ +K++ L+ + +LD+ +N NI I + GL + I
Sbjct 101 QNLPNLQYLLISNTGIKHLPDV-HKIHSLQKV-LLDIQDNINIHTIERNSFVGLSFESVI 158
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL-ESNGFDEIPVEVFKDLFELKIIDL 593
L L N + + A G + L LNL ++N +E+P +VF I+D+
Sbjct 159 LWLNKNGIQEIHNSAFNG---------TQLDELNLSDNNNLEELPNDVFHGASGPVILDI 209
Query 594 GLNNLNTLPASVFNNQVSLKS---LNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
+++LP+ N L++ NL+K + ++EK V L E + + P C
Sbjct 210 SRTRIHSLPSYGLENLKKLRARSTYNLKK--LPTLEKLVA------LMEASLTY-PSHC- 259
Query 651 CESIAWFVNWINETHTNIPELSSHYLCN 678
F NW I EL H +CN
Sbjct 260 ----CAFANW----RRQISEL--HPICN 277
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/197 (24%), Positives = 90/197 (46%), Gaps = 8/197 (4%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C S+ V C K+T++P DLP N L +LR + F+ + L +++ N +
Sbjct 7 CHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEISQNDV 66
Query 88 SK-LEPELCQKLPMLKVLNLQH-NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ +E ++ LP L + ++ N L ++ + F NL L + + I+ + + +
Sbjct 67 LEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPNLQYLLISNTGIKHLPDVHKIH 126
Query 146 QKNLITLDLSHN-GLSSTKLGTQVQLENLQELL-LSNNKIQALKSEELDIFANSSLKKLE 203
+ LD+ N + + + + V L +L L+ N IQ + + F + L +L
Sbjct 127 SLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKNGIQEIHNSA---FNGTQLDELN 183
Query 204 LS-SNQIKEFSPGCFHA 219
LS +N ++E FH
Sbjct 184 LSDNNNLEELPNDVFHG 200
>4ay9_G X FOLLICLE-STIMULATING HORMONE RECEPTOR
Length=354
Score = 44.7 bits (104), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 69/268 (26%), Positives = 120/268 (45%), Gaps = 38/268 (14%)
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS-YNKYLQLTRNSF 476
K+ I+ AFS G LE +++ N++ + + + L + EI + N L + +F
Sbjct 41 KLRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAF 100
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN-NIANINDDMLEGLE-KLEI 534
+P+LQ L++ +K++ L+ + +LD+ +N NI I + GL + I
Sbjct 101 QNLPNLQYLLISNTGIKHLPDV-HKIHSLQKV-LLDIQDNINIHTIERNSFVGLSFESVI 158
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL-ESNGFDEIPVEVFKDLFELKIIDL 593
L L N + + A G + L LNL ++N +E+P +VF I+D+
Sbjct 159 LWLNKNGIQEIHNSAFNG---------TQLDELNLSDNNNLEELPNDVFHGASGPVILDI 209
Query 594 GLNNLNTLPASVFNNQVSLKS---LNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
+++LP+ N L++ NL+K + ++EK V L E + + P C
Sbjct 210 SRTRIHSLPSYGLENLKKLRARSTYNLKK--LPTLEKLVA------LMEASLTY-PSHC- 259
Query 651 CESIAWFVNWINETHTNIPELSSHYLCN 678
F NW I EL H +CN
Sbjct 260 ----CAFANW----RRQISEL--HPICN 277
Score = 42.7 bits (99), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 47/197 (24%), Positives = 90/197 (46%), Gaps = 8/197 (4%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C S+ V C K+T++P DLP N L +LR + F+ + L +++ N +
Sbjct 7 CHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEISQNDV 66
Query 88 SK-LEPELCQKLPMLKVLNLQH-NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ +E ++ LP L + ++ N L ++ + F NL L + + I+ + + +
Sbjct 67 LEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPNLQYLLISNTGIKHLPDVHKIH 126
Query 146 QKNLITLDLSHN-GLSSTKLGTQVQLENLQELL-LSNNKIQALKSEELDIFANSSLKKLE 203
+ LD+ N + + + + V L +L L+ N IQ + + F + L +L
Sbjct 127 SLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKNGIQEIHNSA---FNGTQLDELN 183
Query 204 LS-SNQIKEFSPGCFHA 219
LS +N ++E FH
Sbjct 184 LSDNNNLEELPNDVFHG 200
>6obn_C C Protein phosphatase 1 regulatory subunit 7
Length=310
Score = 43.9 bits (102), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 87/178 (49%), Gaps = 32/178 (18%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL- 114
L+L NQ++++ N ++L LD+ FN + +E KL LK L L +N++S++
Sbjct 75 LDLYDNQIKKIE--NLEALTELEILDISFNLLRNIEG--VDKLTRLKKLFLVNNKISKIE 130
Query 115 --------------SDKTFAF-----CTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
S++ A TNL L L N I K++N + NL L +
Sbjct 131 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALT--NLTVLSMQ 188
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
N L TK+ L NL+EL LS+N I+ ++ E N+ L L+++SN+IK+
Sbjct 189 SNRL--TKIEGLQNLVNLRELYLSHNGIEVIEGLE----NNNKLTMLDIASNRIKKIE 240
Score = 37.4 bits (85), Expect = 0.56, Method: Compositional matrix adjust.
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 24/185 (13%)
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F ++ ++ L LR+ +K +++ + L++L LDL +N I I + LE L +LEI
Sbjct 43 GFEVLKKVKTLCLRQNLIKCIEN----LEELQSLRELDLYDNQIKKIEN--LEALTELEI 96
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
LD+ N L I + L+ L L L +N +I E +L +L++++LG
Sbjct 97 LDISFNLLR----------NIEGVDKLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELG 144
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
N + + + +L+SL L KN IT ++ A NLT L M+ N E +
Sbjct 145 SNRIRAIEN--IDTLTNLESLFLGKNKITKLQNL---DALTNLTVLSMQSNRL-TKIEGL 198
Query 655 AWFVN 659
VN
Sbjct 199 QNLVN 203
>8b5r_I S Protein phosphatase 1 regulatory subunit 7
Length=360
Score = 43.9 bits (102), Expect = 0.005, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 87/178 (49%), Gaps = 32/178 (18%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL- 114
L+L NQ++++ N ++L LD+ FN + +E KL LK L L +N++S++
Sbjct 125 LDLYDNQIKKIE--NLEALTELEILDISFNLLRNIEG--VDKLTRLKKLFLVNNKISKIE 180
Query 115 --------------SDKTFAF-----CTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
S++ A TNL L L N I K++N + NL L +
Sbjct 181 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALT--NLTVLSMQ 238
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
N L TK+ L NL+EL LS+N I+ ++ E N+ L L+++SN+IK+
Sbjct 239 SNRL--TKIEGLQNLVNLRELYLSHNGIEVIEGLE----NNNKLTMLDIASNRIKKIE 290
Score = 37.4 bits (85), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 24/185 (13%)
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F ++ ++ L LR+ +K +++ + L++L LDL +N I I + LE L +LEI
Sbjct 93 GFEVLKKVKTLCLRQNLIKCIEN----LEELQSLRELDLYDNQIKKIEN--LEALTELEI 146
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
LD+ N L I + L+ L L L +N +I E +L +L++++LG
Sbjct 147 LDISFNLLR----------NIEGVDKLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELG 194
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
N + + + +L+SL L KN IT ++ A NLT L M+ N E +
Sbjct 195 SNRIRAIEN--IDTLTNLESLFLGKNKITKLQNL---DALTNLTVLSMQSNRL-TKIEGL 248
Query 655 AWFVN 659
VN
Sbjct 249 QNLVN 253
>8u5g_B B Protein phosphatase 1 regulatory subunit 7
Length=310
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 87/178 (49%), Gaps = 32/178 (18%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL- 114
L+L NQ++++ N ++L LD+ FN + +E KL LK L L +N++S++
Sbjct 75 LDLYDNQIKKIE--NLEALTELEILDISFNLLRNIEG--VDKLTRLKKLFLVNNKISKIE 130
Query 115 --------------SDKTFAF-----CTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
S++ A TNL L L N I K++N + NL L +
Sbjct 131 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALT--NLTVLSMQ 188
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
N L TK+ L NL+EL LS+N I+ ++ E N+ L L+++SN+IK+
Sbjct 189 SNRL--TKIEGLQNLVNLRELYLSHNGIEVIEGLE----NNNKLTMLDIASNRIKKIE 240
Score = 37.4 bits (85), Expect = 0.60, Method: Compositional matrix adjust.
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 24/185 (13%)
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F ++ ++ L LR+ +K +++ + L++L LDL +N I I + LE L +LEI
Sbjct 43 GFEVLKKVKTLCLRQNLIKCIEN----LEELQSLRELDLYDNQIKKIEN--LEALTELEI 96
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
LD+ N L I + L+ L L L +N +I E +L +L++++LG
Sbjct 97 LDISFNLLR----------NIEGVDKLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELG 144
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
N + + + +L+SL L KN IT ++ A NLT L M+ N E +
Sbjct 145 SNRIRAIEN--IDTLTNLESLFLGKNKITKLQNL---DALTNLTVLSMQSNRL-TKIEGL 198
Query 655 AWFVN 659
VN
Sbjct 199 QNLVN 203
>6obn_D D Protein phosphatase 1 regulatory subunit 7
Length=310
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 87/178 (49%), Gaps = 32/178 (18%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL- 114
L+L NQ++++ N ++L LD+ FN + +E KL LK L L +N++S++
Sbjct 75 LDLYDNQIKKIE--NLEALTELEILDISFNLLRNIEG--VDKLTRLKKLFLVNNKISKIE 130
Query 115 --------------SDKTFAF-----CTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
S++ A TNL L L N I K++N + NL L +
Sbjct 131 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALT--NLTVLSMQ 188
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
N L TK+ L NL+EL LS+N I+ ++ E N+ L L+++SN+IK+
Sbjct 189 SNRL--TKIEGLQNLVNLRELYLSHNGIEVIEGLE----NNNKLTMLDIASNRIKKIE 240
Score = 37.4 bits (85), Expect = 0.57, Method: Compositional matrix adjust.
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 24/185 (13%)
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F ++ ++ L LR+ +K +++ + L++L LDL +N I I + LE L +LEI
Sbjct 43 GFEVLKKVKTLCLRQNLIKCIEN----LEELQSLRELDLYDNQIKKIEN--LEALTELEI 96
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
LD+ N L I + L+ L L L +N +I E +L +L++++LG
Sbjct 97 LDISFNLLR----------NIEGVDKLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELG 144
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
N + + + +L+SL L KN IT ++ A NLT L M+ N E +
Sbjct 145 SNRIRAIEN--IDTLTNLESLFLGKNKITKLQNL---DALTNLTVLSMQSNRL-TKIEGL 198
Query 655 AWFVN 659
VN
Sbjct 199 QNLVN 203
>6obp_B C Protein phosphatase 1 regulatory subunit 7
Length=310
Score = 43.5 bits (101), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 87/178 (49%), Gaps = 32/178 (18%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL- 114
L+L NQ++++ N ++L LD+ FN + +E KL LK L L +N++S++
Sbjct 75 LDLYDNQIKKIE--NLEALTELEILDISFNLLRNIEG--VDKLTRLKKLFLVNNKISKIE 130
Query 115 --------------SDKTFAF-----CTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
S++ A TNL L L N I K++N + NL L +
Sbjct 131 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALT--NLTVLSMQ 188
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
N L TK+ L NL+EL LS+N I+ ++ E N+ L L+++SN+IK+
Sbjct 189 SNRL--TKIEGLQNLVNLRELYLSHNGIEVIEGLE----NNNKLTMLDIASNRIKKIE 240
Score = 37.4 bits (85), Expect = 0.68, Method: Compositional matrix adjust.
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 24/185 (13%)
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F ++ ++ L LR+ +K +++ + L++L LDL +N I I + LE L +LEI
Sbjct 43 GFEVLKKVKTLCLRQNLIKCIEN----LEELQSLRELDLYDNQIKKIEN--LEALTELEI 96
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
LD+ N L I + L+ L L L +N +I E +L +L++++LG
Sbjct 97 LDISFNLLR----------NIEGVDKLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELG 144
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
N + + + +L+SL L KN IT ++ A NLT L M+ N E +
Sbjct 145 SNRIRAIEN--IDTLTNLESLFLGKNKITKLQNL---DALTNLTVLSMQSNRL-TKIEGL 198
Query 655 AWFVN 659
VN
Sbjct 199 QNLVN 203
>6hkw_A A Protein phosphatase 1 regulatory subunit 7
Length=363
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 87/178 (49%), Gaps = 32/178 (18%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL- 114
L+L NQ++++ N ++L LD+ FN + +E KL LK L L +N++S++
Sbjct 128 LDLYDNQIKKIE--NLEALTELEILDISFNLLRNIEG--VDKLTRLKKLFLVNNKISKIE 183
Query 115 --------------SDKTFAF-----CTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
S++ A TNL L L N I K++N + NL L +
Sbjct 184 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALT--NLTVLSMQ 241
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
N L TK+ L NL+EL LS+N I+ ++ E N+ L L+++SN+IK+
Sbjct 242 SNRL--TKIEGLQNLVNLRELYLSHNGIEVIEGLE----NNNKLTMLDIASNRIKKIE 293
Score = 37.0 bits (84), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 24/185 (13%)
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F ++ ++ L LR+ +K +++ + L++L LDL +N I I + LE L +LEI
Sbjct 96 GFEVLKKVKTLCLRQNLIKCIEN----LEELQSLRELDLYDNQIKKIEN--LEALTELEI 149
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
LD+ N L I + L+ L L L +N +I E +L +L++++LG
Sbjct 150 LDISFNLLRN----------IEGVDKLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELG 197
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
N + + + +L+SL L KN IT ++ A NLT L M+ N E +
Sbjct 198 SNRIRAIEN--IDTLTNLESLFLGKNKITKLQNL---DALTNLTVLSMQSNRL-TKIEGL 251
Query 655 AWFVN 659
VN
Sbjct 252 QNLVN 256
>6hkw_E E Protein phosphatase 1 regulatory subunit 7
Length=363
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 87/178 (49%), Gaps = 32/178 (18%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL- 114
L+L NQ++++ N ++L LD+ FN + +E KL LK L L +N++S++
Sbjct 128 LDLYDNQIKKIE--NLEALTELEILDISFNLLRNIEG--VDKLTRLKKLFLVNNKISKIE 183
Query 115 --------------SDKTFAF-----CTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
S++ A TNL L L N I K++N + NL L +
Sbjct 184 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALT--NLTVLSMQ 241
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
N L TK+ L NL+EL LS+N I+ ++ E N+ L L+++SN+IK+
Sbjct 242 SNRL--TKIEGLQNLVNLRELYLSHNGIEVIEGLE----NNNKLTMLDIASNRIKKIE 293
Score = 37.0 bits (84), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 24/185 (13%)
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F ++ ++ L LR+ +K +++ + L++L LDL +N I I + LE L +LEI
Sbjct 96 GFEVLKKVKTLCLRQNLIKCIEN----LEELQSLRELDLYDNQIKKIEN--LEALTELEI 149
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
LD+ N L I + L+ L L L +N +I E +L +L++++LG
Sbjct 150 LDISFNLLRN----------IEGVDKLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELG 197
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
N + + + +L+SL L KN IT ++ A NLT L M+ N E +
Sbjct 198 SNRIRAIEN--IDTLTNLESLFLGKNKITKLQNL---DALTNLTVLSMQSNRL-TKIEGL 251
Query 655 AWFVN 659
VN
Sbjct 252 QNLVN 256
>6hkw_B B Protein phosphatase 1 regulatory subunit 7
Length=363
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 87/178 (49%), Gaps = 32/178 (18%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL- 114
L+L NQ++++ N ++L LD+ FN + +E KL LK L L +N++S++
Sbjct 128 LDLYDNQIKKIE--NLEALTELEILDISFNLLRNIEG--VDKLTRLKKLFLVNNKISKIE 183
Query 115 --------------SDKTFAF-----CTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
S++ A TNL L L N I K++N + NL L +
Sbjct 184 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALT--NLTVLSMQ 241
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
N L TK+ L NL+EL LS+N I+ ++ E N+ L L+++SN+IK+
Sbjct 242 SNRL--TKIEGLQNLVNLRELYLSHNGIEVIEGLE----NNNKLTMLDIASNRIKKIE 293
Score = 37.0 bits (84), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 24/185 (13%)
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F ++ ++ L LR+ +K +++ + L++L LDL +N I I + LE L +LEI
Sbjct 96 GFEVLKKVKTLCLRQNLIKCIEN----LEELQSLRELDLYDNQIKKIEN--LEALTELEI 149
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
LD+ N L I + L+ L L L +N +I E +L +L++++LG
Sbjct 150 LDISFNLLRN----------IEGVDKLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELG 197
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
N + + + +L+SL L KN IT ++ A NLT L M+ N E +
Sbjct 198 SNRIRAIEN--IDTLTNLESLFLGKNKITKLQNL---DALTNLTVLSMQSNRL-TKIEGL 251
Query 655 AWFVN 659
VN
Sbjct 252 QNLVN 256
>6hkw_C C Protein phosphatase 1 regulatory subunit 7
Length=363
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 87/178 (49%), Gaps = 32/178 (18%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL- 114
L+L NQ++++ N ++L LD+ FN + +E KL LK L L +N++S++
Sbjct 128 LDLYDNQIKKIE--NLEALTELEILDISFNLLRNIEG--VDKLTRLKKLFLVNNKISKIE 183
Query 115 --------------SDKTFAF-----CTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
S++ A TNL L L N I K++N + NL L +
Sbjct 184 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALT--NLTVLSMQ 241
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
N L TK+ L NL+EL LS+N I+ ++ E N+ L L+++SN+IK+
Sbjct 242 SNRL--TKIEGLQNLVNLRELYLSHNGIEVIEGLE----NNNKLTMLDIASNRIKKIE 293
Score = 37.0 bits (84), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 24/185 (13%)
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F ++ ++ L LR+ +K +++ + L++L LDL +N I I + LE L +LEI
Sbjct 96 GFEVLKKVKTLCLRQNLIKCIEN----LEELQSLRELDLYDNQIKKIEN--LEALTELEI 149
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
LD+ N L I + L+ L L L +N +I E +L +L++++LG
Sbjct 150 LDISFNLLRN----------IEGVDKLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELG 197
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
N + + + +L+SL L KN IT ++ A NLT L M+ N E +
Sbjct 198 SNRIRAIEN--IDTLTNLESLFLGKNKITKLQNL---DALTNLTVLSMQSNRL-TKIEGL 251
Query 655 AWFVN 659
VN
Sbjct 252 QNLVN 256
>6hkw_D D Protein phosphatase 1 regulatory subunit 7
Length=363
Score = 43.9 bits (102), Expect = 0.006, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 87/178 (49%), Gaps = 32/178 (18%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL- 114
L+L NQ++++ N ++L LD+ FN + +E KL LK L L +N++S++
Sbjct 128 LDLYDNQIKKIE--NLEALTELEILDISFNLLRNIEG--VDKLTRLKKLFLVNNKISKIE 183
Query 115 --------------SDKTFAF-----CTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
S++ A TNL L L N I K++N + NL L +
Sbjct 184 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALT--NLTVLSMQ 241
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
N L TK+ L NL+EL LS+N I+ ++ E N+ L L+++SN+IK+
Sbjct 242 SNRL--TKIEGLQNLVNLRELYLSHNGIEVIEGLE----NNNKLTMLDIASNRIKKIE 293
Score = 37.0 bits (84), Expect = 0.92, Method: Compositional matrix adjust.
Identities = 54/185 (29%), Positives = 89/185 (48%), Gaps = 24/185 (13%)
Query 475 SFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEI 534
F ++ ++ L LR+ +K +++ + L++L LDL +N I I + LE L +LEI
Sbjct 96 GFEVLKKVKTLCLRQNLIKCIEN----LEELQSLRELDLYDNQIKKIEN--LEALTELEI 149
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLG 594
LD+ N L I + L+ L L L +N +I E +L +L++++LG
Sbjct 150 LDISFNLLRN----------IEGVDKLTRLKKLFLVNNKISKI--ENLSNLHQLQMLELG 197
Query 595 LNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESI 654
N + + + +L+SL L KN IT ++ A NLT L M+ N E +
Sbjct 198 SNRIRAIEN--IDTLTNLESLFLGKNKITKLQNL---DALTNLTVLSMQSNRL-TKIEGL 251
Query 655 AWFVN 659
VN
Sbjct 252 QNLVN 256
>4mqw_I Z Follicle-stimulating hormone receptor
Length=365
Score = 43.9 bits (102), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 62/250 (25%), Positives = 112/250 (45%), Gaps = 32/250 (13%)
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS-YNKYLQLTRNSF 476
K+ I+ AFS G LE +++ N++ + + + L + EI + N L + +F
Sbjct 42 KLRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAF 101
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN-NIANINDDMLEGLE-KLEI 534
+P+LQ L++ +K++ L+ + +LD+ +N NI I + GL + I
Sbjct 102 QNLPNLQYLLISNTGIKHLPDV-HKIHSLQKV-LLDIQDNINIHTIERNSFVGLSFESVI 159
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL-ESNGFDEIPVEVFKDLFELKIIDL 593
L L N + + A G + L LNL ++N +E+P +VF I+D+
Sbjct 160 LWLNKNGIQEIHNSAFNG---------TQLDELNLSDNNNLEELPNDVFHGASGPVILDI 210
Query 594 GLNNLNTLPASVFNNQVSLKS---LNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
+++LP+ N L++ NL+K + ++EK V L E + + C
Sbjct 211 SRTRIHSLPSYGLENLKKLRARSTYNLKK--LPTLEKLVA------LMEASLTYPSHCCA 262
Query 651 CESIAWFVNW 660
F NW
Sbjct 263 ------FANW 266
Score = 43.1 bits (100), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 47/197 (24%), Positives = 90/197 (46%), Gaps = 8/197 (4%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C S+ V C K+T++P DLP N L +LR + F+ + L +++ N +
Sbjct 8 CHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEISQNDV 67
Query 88 SK-LEPELCQKLPMLKVLNLQH-NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ +E ++ LP L + ++ N L ++ + F NL L + + I+ + + +
Sbjct 68 LEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPNLQYLLISNTGIKHLPDVHKIH 127
Query 146 QKNLITLDLSHN-GLSSTKLGTQVQLENLQELL-LSNNKIQALKSEELDIFANSSLKKLE 203
+ LD+ N + + + + V L +L L+ N IQ + + F + L +L
Sbjct 128 SLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKNGIQEIHNSA---FNGTQLDELN 184
Query 204 LS-SNQIKEFSPGCFHA 219
LS +N ++E FH
Sbjct 185 LSDNNNLEELPNDVFHG 201
>6mky_A A Protein phosphatase 1 regulatory subunit 7
Length=261
Score = 43.1 bits (100), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 87/178 (49%), Gaps = 32/178 (18%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL- 114
L+L NQ++++ N ++L LD+ FN + +E KL LK L L +N++S++
Sbjct 26 LDLYDNQIKKIE--NLEALTELEILDISFNLLRNIEG--VDKLTRLKKLFLVNNKISKIE 81
Query 115 --------------SDKTFAF-----CTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
S++ A TNL L L N I K++N + NL L +
Sbjct 82 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALT--NLTVLSMQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
N L TK+ L NL+EL LS+N I+ ++ E N+ L L+++SN+IK+
Sbjct 140 SNRL--TKIEGLQNLVNLRELYLSHNGIEVIEGLE----NNNKLTMLDIASNRIKKIE 191
Score = 34.7 bits (78), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 49/158 (31%), Positives = 75/158 (47%), Gaps = 20/158 (13%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
+ L++L LDL +N I I + LE L +LEILD+ N L I + L
Sbjct 17 LEELQSLRELDLYDNQIKKIEN--LEALTELEILDISFNLLRN----------IEGVDKL 64
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
+ L L L +N +I E +L +L++++LG N + + + +L+SL L KN
Sbjct 65 TRLKKLFLVNNKISKI--ENLSNLHQLQMLELGSNRIRAIEN--IDTLTNLESLFLGKNK 120
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVN 659
IT ++ A NLT L M+ N E + VN
Sbjct 121 ITKLQN---LDALTNLTVLSMQSNRL-TKIEGLQNLVN 154
>4mqw_C X Follicle-stimulating hormone receptor
Length=365
Score = 43.5 bits (101), Expect = 0.007, Method: Compositional matrix adjust.
Identities = 62/250 (25%), Positives = 112/250 (45%), Gaps = 32/250 (13%)
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS-YNKYLQLTRNSF 476
K+ I+ AFS G LE +++ N++ + + + L + EI + N L + +F
Sbjct 42 KLRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAF 101
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN-NIANINDDMLEGLE-KLEI 534
+P+LQ L++ +K++ L+ + +LD+ +N NI I + GL + I
Sbjct 102 QNLPNLQYLLISNTGIKHLPDV-HKIHSLQKV-LLDIQDNINIHTIERNSFVGLSFESVI 159
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL-ESNGFDEIPVEVFKDLFELKIIDL 593
L L N + + A G + L LNL ++N +E+P +VF I+D+
Sbjct 160 LWLNKNGIQEIHNSAFNG---------TQLDELNLSDNNNLEELPNDVFHGASGPVILDI 210
Query 594 GLNNLNTLPASVFNNQVSLKS---LNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
+++LP+ N L++ NL+K + ++EK V L E + + C
Sbjct 211 SRTRIHSLPSYGLENLKKLRARSTYNLKK--LPTLEKLVA------LMEASLTYPSHCCA 262
Query 651 CESIAWFVNW 660
F NW
Sbjct 263 ------FANW 266
Score = 42.7 bits (99), Expect = 0.014, Method: Compositional matrix adjust.
Identities = 47/197 (24%), Positives = 90/197 (46%), Gaps = 8/197 (4%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C S+ V C K+T++P DLP N L +LR + F+ + L +++ N +
Sbjct 8 CHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEISQNDV 67
Query 88 SK-LEPELCQKLPMLKVLNLQH-NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ +E ++ LP L + ++ N L ++ + F NL L + + I+ + + +
Sbjct 68 LEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPNLQYLLISNTGIKHLPDVHKIH 127
Query 146 QKNLITLDLSHN-GLSSTKLGTQVQLENLQELL-LSNNKIQALKSEELDIFANSSLKKLE 203
+ LD+ N + + + + V L +L L+ N IQ + + F + L +L
Sbjct 128 SLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKNGIQEIHNSA---FNGTQLDELN 184
Query 204 LS-SNQIKEFSPGCFHA 219
LS +N ++E FH
Sbjct 185 LSDNNNLEELPNDVFHG 201
>6mky_B B Protein phosphatase 1 regulatory subunit 7
Length=261
Score = 43.1 bits (100), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 54/178 (30%), Positives = 87/178 (49%), Gaps = 32/178 (18%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL- 114
L+L NQ++++ N ++L LD+ FN + +E KL LK L L +N++S++
Sbjct 26 LDLYDNQIKKIE--NLEALTELEILDISFNLLRNIEG--VDKLTRLKKLFLVNNKISKIE 81
Query 115 --------------SDKTFAF-----CTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
S++ A TNL L L N I K++N + NL L +
Sbjct 82 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALT--NLTVLSMQ 139
Query 156 HNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
N L TK+ L NL+EL LS+N I+ ++ E N+ L L+++SN+IK+
Sbjct 140 SNRL--TKIEGLQNLVNLRELYLSHNGIEVIEGLE----NNNKLTMLDIASNRIKKIE 191
Score = 34.7 bits (78), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 49/158 (31%), Positives = 75/158 (47%), Gaps = 20/158 (13%)
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
+ L++L LDL +N I I + LE L +LEILD+ N L I + L
Sbjct 17 LEELQSLRELDLYDNQIKKIEN--LEALTELEILDISFNLLR----------NIEGVDKL 64
Query 562 SHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNL 621
+ L L L +N +I E +L +L++++LG N + + + +L+SL L KN
Sbjct 65 TRLKKLFLVNNKISKI--ENLSNLHQLQMLELGSNRIRAIEN--IDTLTNLESLFLGKNK 120
Query 622 ITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVN 659
IT ++ A NLT L M+ N E + VN
Sbjct 121 ITKLQN---LDALTNLTVLSMQSNRL-TKIEGLQNLVN 154
>8i2h_A A Follicle-stimulating hormone receptor
Length=682
Score = 43.9 bits (102), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 63/256 (25%), Positives = 113/256 (44%), Gaps = 32/256 (13%)
Query 412 LNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYL-SYNKYLQ 470
L K+ I+ AFS G LE +++ N++ + + + L + EI + N L
Sbjct 38 LRFVLTKLRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLY 97
Query 471 LTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN-NIANINDDMLEGL 529
+ +F +P+LQ L++ +K++ L+ + +LD+ +N NI I + GL
Sbjct 98 INPEAFQNLPNLQYLLISNTGIKHLPDV-HKIHSLQKV-LLDIQDNINIHTIERNSFVGL 155
Query 530 E-KLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL-ESNGFDEIPVEVFKDLFE 587
+ IL L N + + A G + L LNL ++N +E+P +VF
Sbjct 156 SFESVILWLNKNGIQEIHNCAFNG---------TQLDELNLSDNNNLEELPNDVFHGASG 206
Query 588 LKIIDLGLNNLNTLPASVFNNQVSLKS---LNLQKNLITSVEKKVFGPAFRNLTELDMRF 644
I+D+ +++LP+ N L++ NL+K + ++EK V L E + +
Sbjct 207 PVILDISRTRIHSLPSYGLENLKKLRARSTYNLKK--LPTLEKLV------ALMEASLTY 258
Query 645 NPFDCTCESIAWFVNW 660
C F NW
Sbjct 259 PSHCCA------FANW 268
Score = 43.1 bits (100), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 47/197 (24%), Positives = 90/197 (46%), Gaps = 8/197 (4%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C S+ V C K+T++P DLP N L +LR + F+ + L +++ N +
Sbjct 10 CHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEISQNDV 69
Query 88 SK-LEPELCQKLPMLKVLNLQH-NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ +E ++ LP L + ++ N L ++ + F NL L + + I+ + + +
Sbjct 70 LEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPNLQYLLISNTGIKHLPDVHKIH 129
Query 146 QKNLITLDLSHN-GLSSTKLGTQVQLENLQELL-LSNNKIQALKSEELDIFANSSLKKLE 203
+ LD+ N + + + + V L +L L+ N IQ + + F + L +L
Sbjct 130 SLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKNGIQEIHNCA---FNGTQLDELN 186
Query 204 LS-SNQIKEFSPGCFHA 219
LS +N ++E FH
Sbjct 187 LSDNNNLEELPNDVFHG 203
>1xwd_F F Follicle stimulating hormone receptor
Length=252
Score = 42.7 bits (99), Expect = 0.008, Method: Compositional matrix adjust.
Identities = 47/197 (24%), Positives = 90/197 (46%), Gaps = 8/197 (4%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C S+ V C K+T++P DLP N L +LR + F+ + L +++ N +
Sbjct 7 CHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEISQNDV 66
Query 88 SK-LEPELCQKLPMLKVLNLQH-NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ +E ++ LP L + ++ N L ++ + F NL L + + I+ + + +
Sbjct 67 LEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPNLQYLLISNTGIKHLPDVHKIH 126
Query 146 QKNLITLDLSHN-GLSSTKLGTQVQLENLQELL-LSNNKIQALKSEELDIFANSSLKKLE 203
+ LD+ N + + + + V L +L L+ N IQ + + F + L +L
Sbjct 127 SLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKNGIQEIHN---CAFNGTQLDELN 183
Query 204 LS-SNQIKEFSPGCFHA 219
LS +N ++E FH
Sbjct 184 LSDNNNLEELPNDVFHG 200
Score = 42.0 bits (97), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 50/201 (25%), Positives = 94/201 (47%), Gaps = 15/201 (7%)
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS-YNKYLQLTRNSF 476
K+ I+ AFS G LE +++ N++ + + + L + EI + N L + +F
Sbjct 41 KLRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAF 100
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN-NIANINDDMLEGLE-KLEI 534
+P+LQ L++ +K++ L+ + +LD+ +N NI I + GL + I
Sbjct 101 QNLPNLQYLLISNTGIKHL-PDVHKIHSLQKV-LLDIQDNINIHTIERNSFVGLSFESVI 158
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL-ESNGFDEIPVEVFKDLFELKIIDL 593
L L N + + A G + L LNL ++N +E+P +VF I+D+
Sbjct 159 LWLNKNGIQEIHNCAFNG---------TQLDELNLSDNNNLEELPNDVFHGASGPVILDI 209
Query 594 GLNNLNTLPASVFNNQVSLKS 614
+++LP+ N L++
Sbjct 210 SRTRIHSLPSYGLENLKKLRA 230
>4mqw_F Y Follicle-stimulating hormone receptor
Length=365
Score = 43.5 bits (101), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 62/250 (25%), Positives = 112/250 (45%), Gaps = 32/250 (13%)
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS-YNKYLQLTRNSF 476
K+ I+ AFS G LE +++ N++ + + + L + EI + N L + +F
Sbjct 42 KLRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAF 101
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN-NIANINDDMLEGLE-KLEI 534
+P+LQ L++ +K++ L+ + +LD+ +N NI I + GL + I
Sbjct 102 QNLPNLQYLLISNTGIKHLPDV-HKIHSLQKV-LLDIQDNINIHTIERNSFVGLSFESVI 159
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL-ESNGFDEIPVEVFKDLFELKIIDL 593
L L N + + A G + L LNL ++N +E+P +VF I+D+
Sbjct 160 LWLNKNGIQEIHNSAFNG---------TQLDELNLSDNNNLEELPNDVFHGASGPVILDI 210
Query 594 GLNNLNTLPASVFNNQVSLKS---LNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCT 650
+++LP+ N L++ NL+K + ++EK V L E + + C
Sbjct 211 SRTRIHSLPSYGLENLKKLRARSTYNLKK--LPTLEKLVA------LMEASLTYPSHCCA 262
Query 651 CESIAWFVNW 660
F NW
Sbjct 263 ------FANW 266
Score = 43.5 bits (101), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 47/197 (24%), Positives = 90/197 (46%), Gaps = 8/197 (4%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C S+ V C K+T++P DLP N L +LR + F+ + L +++ N +
Sbjct 8 CHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEISQNDV 67
Query 88 SK-LEPELCQKLPMLKVLNLQH-NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ +E ++ LP L + ++ N L ++ + F NL L + + I+ + + +
Sbjct 68 LEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPNLQYLLISNTGIKHLPDVHKIH 127
Query 146 QKNLITLDLSHN-GLSSTKLGTQVQLENLQELL-LSNNKIQALKSEELDIFANSSLKKLE 203
+ LD+ N + + + + V L +L L+ N IQ + + F + L +L
Sbjct 128 SLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKNGIQEIHNSA---FNGTQLDELN 184
Query 204 LS-SNQIKEFSPGCFHA 219
LS +N ++E FH
Sbjct 185 LSDNNNLEELPNDVFHG 201
>1xwd_C C Follicle stimulating hormone receptor
Length=252
Score = 42.4 bits (98), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 47/197 (24%), Positives = 90/197 (46%), Gaps = 8/197 (4%)
Query 28 CTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTI 87
C S+ V C K+T++P DLP N L +LR + F+ + L +++ N +
Sbjct 7 CHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEISQNDV 66
Query 88 SK-LEPELCQKLPMLKVLNLQH-NELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVK 145
+ +E ++ LP L + ++ N L ++ + F NL L + + I+ + + +
Sbjct 67 LEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLPNLQYLLISNTGIKHLPDVHKIH 126
Query 146 QKNLITLDLSHN-GLSSTKLGTQVQLENLQELL-LSNNKIQALKSEELDIFANSSLKKLE 203
+ LD+ N + + + + V L +L L+ N IQ + + F + L +L
Sbjct 127 SLQKVLLDIQDNINIHTIERNSFVGLSFESVILWLNKNGIQEIHN---CAFNGTQLDELN 183
Query 204 LS-SNQIKEFSPGCFHA 219
LS +N ++E FH
Sbjct 184 LSDNNNLEELPNDVFHG 200
Score = 42.0 bits (97), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 50/201 (25%), Positives = 94/201 (47%), Gaps = 15/201 (7%)
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLS-YNKYLQLTRNSF 476
K+ I+ AFS G LE +++ N++ + + + L + EI + N L + +F
Sbjct 41 KLRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAF 100
Query 477 ALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNN-NIANINDDMLEGLE-KLEI 534
+P+LQ L++ +K++ L+ + +LD+ +N NI I + GL + I
Sbjct 101 QNLPNLQYLLISNTGIKHLPDV-HKIHSLQKV-LLDIQDNINIHTIERNSFVGLSFESVI 158
Query 535 LDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL-ESNGFDEIPVEVFKDLFELKIIDL 593
L L N + + A G + L LNL ++N +E+P +VF I+D+
Sbjct 159 LWLNKNGIQEIHNCAFNG---------TQLDELNLSDNNNLEELPNDVFHGASGPVILDI 209
Query 594 GLNNLNTLPASVFNNQVSLKS 614
+++LP+ N L++
Sbjct 210 SRTRIHSLPSYGLENLKKLRA 230
>4z64_A A Phytosulfokine receptor 1
Length=631
Score = 43.1 bits (100), Expect = 0.015, Method: Compositional matrix adjust.
Identities = 74/312 (24%), Positives = 136/312 (44%), Gaps = 23/312 (7%)
Query 70 NFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELH 129
N T L SLD+G N + PE LK +NL N ++F +L+
Sbjct 288 NCTAMIALNSLDLGTNRFNGRLPENLPDCKRLKNVNLARNTFHGQVPESFKNFESLSYFS 347
Query 130 LMSNSIQKIKNNPFVKQ--KNLITLDLSHN-GLSSTKLGTQVQLENLQELLLSNNKIQAL 186
L ++S+ I + + Q KNL TL L+ N + + + E L+ L+++N ++
Sbjct 348 LSNSSLANISSALGILQHCKNLTTLVLTLNFHGEALPDDSSLHFEKLKVLVVANCRLTGS 407
Query 187 KSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELA 246
L +++ L+ L+LS N++ P LF L L+N + + L +L
Sbjct 408 MPRWLS--SSNELQLLDLSWNRLTGAIPSWIGDFKALFYLDLSNNSFTGEIPKSLT-KLE 464
Query 247 NTSIRNLSLSNSQLS----TTSNTTFLGLKWTNL----TMLDLSYNNLNVVGNDSFAWLP 298
+ + RN+S++ N + L++ + ++L +NNL+ + F L
Sbjct 465 SLTSRNISVNEPSPDFPFFMKRNESARALQYNQIFGFPPTIELGHNNLSGPIWEEFGNLK 524
Query 299 QLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLE 358
+L F L++N + SL G+ ++ L+L + SI + S Q L L
Sbjct 525 KLHVFDLKWNALSGSIPSSLSGMTSLEALDLSNNRLSGSIPV---------SLQQLSFLS 575
Query 359 HLNMEDNDIPGI 370
++ N++ G+
Sbjct 576 KFSVAYNNLSGV 587
Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 133/514 (26%), Positives = 198/514 (39%), Gaps = 101/514 (20%)
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
KNL TLDLS N LS + T + L LQ LS+NK F S + +S
Sbjct 101 KNLQTLDLSSNDLSG-GIPTSINLPALQSFDLSSNK-----------FNGSLPSHICHNS 148
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS---------IRNLSLSN 257
QI+ + G F V L E LCL + + + ++ L+L
Sbjct 149 TQIRVVKLAVNYFAGNFTSGFGKCV-----LLEHLCLGMNDLTGNIPEDLFHLKRLNLLG 203
Query 258 SQLSTTSNTTFLGLK-WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
Q + S + ++ ++L LD+S+N + D F LPQL++F + N
Sbjct 204 IQENRLSGSLSREIRNLSSLVRLDVSWNLFSGEIPDVFDELPQLKFFLGQTNGFIGGIPK 263
Query 317 SLHG-------------LFNVRYLNLKRSFTKQSISLAS------LPKIDDFSFQWLKCL 357
SL L LN S+ L + LP+ + K L
Sbjct 264 SLANSPSLNLLNLRNNSLSGRLMLNCTAMIALNSLDLGTNRFNGRLPE----NLPDCKRL 319
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+++N+ N G F +L Y SLSNS SL +++ + L L LT N
Sbjct 320 KNVNLARNTFHGQVPESFKNFESLSYFSLSNS--SLANISSALGILQHCKNLTTLVLTLN 377
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY---LSYNK------- 467
+ D S H E L + L LTG R L + E+ LS+N+
Sbjct 378 FHGEALPDDSSL--HFEKLKV-LVVANCRLTGSMPRWLSSSNELQLLDLSWNRLTGAIPS 434
Query 468 ---------YLQLTRNSF-ALVP----SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDL 513
YL L+ NSF +P L+ L R +++ N S PF RN + L
Sbjct 435 WIGDFKALFYLDLSNNSFTGEIPKSLTKLESLTSRNISV-NEPSPDFPFFMKRNESARAL 493
Query 514 SNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG-LSHLHILNLESN 572
N I ++L HNNL+ GPI+ G L LH+ +L+ N
Sbjct 494 QYNQIFGFP----------PTIELGHNNLS---------GPIWEEFGNLKKLHVFDLKWN 534
Query 573 GFDEIPVEVFKDLFELKIIDLGLNNLN-TLPASV 605
+ L+ +DL N L+ ++P S+
Sbjct 535 ALSGSIPSSLSGMTSLEALDLSNNRLSGSIPVSL 568
>4z63_A A Phytosulfokine receptor 1
Length=631
Score = 42.7 bits (99), Expect = 0.016, Method: Compositional matrix adjust.
Identities = 74/312 (24%), Positives = 136/312 (44%), Gaps = 23/312 (7%)
Query 70 NFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELH 129
N T L SLD+G N + PE LK +NL N ++F +L+
Sbjct 288 NCTAMIALNSLDLGTNRFNGRLPENLPDCKRLKNVNLARNTFHGQVPESFKNFESLSYFS 347
Query 130 LMSNSIQKIKNNPFVKQ--KNLITLDLSHN-GLSSTKLGTQVQLENLQELLLSNNKIQAL 186
L ++S+ I + + Q KNL TL L+ N + + + E L+ L+++N ++
Sbjct 348 LSNSSLANISSALGILQHCKNLTTLVLTLNFHGEALPDDSSLHFEKLKVLVVANCRLTGS 407
Query 187 KSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELA 246
L +++ L+ L+LS N++ P LF L L+N + + L +L
Sbjct 408 MPRWLS--SSNELQLLDLSWNRLTGAIPSWIGDFKALFYLDLSNNSFTGEIPKSLT-KLE 464
Query 247 NTSIRNLSLSNSQLS----TTSNTTFLGLKWTNL----TMLDLSYNNLNVVGNDSFAWLP 298
+ + RN+S++ N + L++ + ++L +NNL+ + F L
Sbjct 465 SLTSRNISVNEPSPDFPFFMKRNESARALQYNQIFGFPPTIELGHNNLSGPIWEEFGNLK 524
Query 299 QLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLE 358
+L F L++N + SL G+ ++ L+L + SI + S Q L L
Sbjct 525 KLHVFDLKWNALSGSIPSSLSGMTSLEALDLSNNRLSGSIPV---------SLQQLSFLS 575
Query 359 HLNMEDNDIPGI 370
++ N++ G+
Sbjct 576 KFSVAYNNLSGV 587
Score = 36.2 bits (82), Expect = 1.7, Method: Compositional matrix adjust.
Identities = 133/514 (26%), Positives = 198/514 (39%), Gaps = 101/514 (20%)
Query 147 KNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSS 206
KNL TLDLS N LS + T + L LQ LS+NK F S + +S
Sbjct 101 KNLQTLDLSSNDLSG-GIPTSINLPALQSFDLSSNK-----------FNGSLPSHICHNS 148
Query 207 NQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANTS---------IRNLSLSN 257
QI+ + G F V L E LCL + + + ++ L+L
Sbjct 149 TQIRVVKLAVNYFAGNFTSGFGKCV-----LLEHLCLGMNDLTGNIPEDLFHLKRLNLLG 203
Query 258 SQLSTTSNTTFLGLK-WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSH 316
Q + S + ++ ++L LD+S+N + D F LPQL++F + N
Sbjct 204 IQENRLSGSLSREIRNLSSLVRLDVSWNLFSGEIPDVFDELPQLKFFLGQTNGFIGGIPK 263
Query 317 SLHG-------------LFNVRYLNLKRSFTKQSISLAS------LPKIDDFSFQWLKCL 357
SL L LN S+ L + LP+ + K L
Sbjct 264 SLANSPSLNLLNLRNNSLSGRLMLNCTAMIALNSLDLGTNRFNGRLPE----NLPDCKRL 319
Query 358 EHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKN 417
+++N+ N G F +L Y SLSNS SL +++ + L L LT N
Sbjct 320 KNVNLARNTFHGQVPESFKNFESLSYFSLSNS--SLANISSALGILQHCKNLTTLVLTLN 377
Query 418 KISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIY---LSYNK------- 467
+ D S H E L + L LTG R L + E+ LS+N+
Sbjct 378 FHGEALPDDSSL--HFEKLKV-LVVANCRLTGSMPRWLSSSNELQLLDLSWNRLTGAIPS 434
Query 468 ---------YLQLTRNSF-ALVP----SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDL 513
YL L+ NSF +P L+ L R +++ N S PF RN + L
Sbjct 435 WIGDFKALFYLDLSNNSFTGEIPKSLTKLESLTSRNISV-NEPSPDFPFFMKRNESARAL 493
Query 514 SNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKG-LSHLHILNLESN 572
N I ++L HNNL+ GPI+ G L LH+ +L+ N
Sbjct 494 QYNQIFGFP----------PTIELGHNNLS---------GPIWEEFGNLKKLHVFDLKWN 534
Query 573 GFDEIPVEVFKDLFELKIIDLGLNNLN-TLPASV 605
+ L+ +DL N L+ ++P S+
Sbjct 535 ALSGSIPSSLSGMTSLEALDLSNNRLSGSIPVSL 568
>2z7x_A A Toll-like receptor 2,Variable lymphocyte receptor B
Length=549
Score = 42.0 bits (97), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 23/186 (12%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
PSLQ L+LR+ L +++ + L+NLT +D+S N+ ++ + + EK++ L+L
Sbjct 361 PSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSM-PETCQWPEKMKYLNLSS 419
Query 540 NNLARLWKHANPGG-PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+ H+ G P L IL++ +N +L +LK + + N L
Sbjct 420 TRI-----HSVTGCIP-------KTLEILDVSNNNL----NLFSLNLPQLKELYISRNKL 463
Query 599 NTLP-ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWF 657
TLP AS+ + LK + +N + SV +F +L ++ + NP+DC+C I +
Sbjct 464 MTLPDASLLPMLLVLK---ISRNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYL 519
Query 658 VNWINE 663
W+N+
Sbjct 520 SRWLNK 525
Score = 40.0 bits (92), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 109/524 (21%), Positives = 210/524 (40%), Gaps = 116/524 (22%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K L+L +N ++ +S+ C NL L L SN I I+ + F +L LDLS+N LS
Sbjct 28 VKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLS 87
Query 161 STK---------------LGTQVQLENLQELLLSNNKIQALKSEELDIFAN--------- 196
+ LG + L K+Q L+ +D F
Sbjct 88 NLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGL 147
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ------LGPSLTEKL-CLELANTS 249
+ L++LE+ ++ ++ + P +I + L L+ Q + +T + CLEL +T
Sbjct 148 TFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTD 207
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFF----L 305
+ S+LST TN + ++ N+ + F + L L
Sbjct 208 LDTFHF--SELSTGE---------TNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLEL 256
Query 306 EYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKID--------DFS--FQWLK 355
E+++ +L+G+ N R + R + ++ ++ D S + +
Sbjct 257 EFDDC------TLNGVGNFRASDNDRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTE 310
Query 356 CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS---------------NSFTSLRTL---- 396
++ + +E++ + + + L +L+YL LS +++ SL+TL
Sbjct 311 RVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQ 370
Query 397 --------TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
T ET ++L + L ++++KN + + W ++ L+L I +T
Sbjct 371 NHLASLEKTGETLLTLKN--LTNIDISKNSFHSM-PETCQWPEKMKYLNLSSTRI-HSVT 426
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV-DSSPSPFQPLRN 507
G + LE I ++ + +P L+ L + R L + D+S P
Sbjct 427 GCIPKTLE-ILDVSNNN------LNLFSLNLPQLKELYISRNKLMTLPDASLLPM----- 474
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANP 551
L +L +S N + ++ D + + L L+ ++W H NP
Sbjct 475 LLVLKISRNQLKSVPDGIFDRLTSLQ----------KIWLHTNP 508
>6nig_D D Toll-like receptor 2,Variable lymphocyte receptor B
Length=576
Score = 42.4 bits (98), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 23/186 (12%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
PSLQ L+LR+ L +++ + L+NLT +D+S N+ ++ + + EK++ L+L
Sbjct 387 PSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSM-PETCQWPEKMKYLNLSS 445
Query 540 NNLARLWKHANPGG-PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+ H+ G P L IL++ +N +L +LK + + N L
Sbjct 446 TRI-----HSVTGCIP-------KTLEILDVSNNNL----NLFSLNLPQLKELYISRNKL 489
Query 599 NTLP-ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWF 657
TLP AS+ + LK + +N + SV +F +L ++ + NP+DC+C I +
Sbjct 490 MTLPDASLLPMLLVLK---ISRNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYL 545
Query 658 VNWINE 663
W+N+
Sbjct 546 SRWLNK 551
Score = 40.4 bits (93), Expect = 0.081, Method: Compositional matrix adjust.
Identities = 112/519 (22%), Positives = 214/519 (41%), Gaps = 106/519 (20%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K L+L +N ++ +S+ C NL L L SN I I+ + F +L LDLS+N LS
Sbjct 54 VKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLS 113
Query 161 STK---------------LGTQVQLENLQELLLSNNKIQALKSEELDIFAN--------- 196
+ LG + L K+Q L+ +D F
Sbjct 114 NLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGL 173
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ------LGPSLTEKL-CLELANTS 249
+ L++LE+ ++ ++ + P +I + L L+ Q + +T + CLEL +T
Sbjct 174 TFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTD 233
Query 250 IRNLSLSNSQLSTTSNT----TFLGLKWTNLT-------------MLDLSYNN--LNVVG 290
+ S T++ TF +K T+ + +L+L +++ LN VG
Sbjct 234 LDTFHFSELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVG 293
Query 291 N-DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL-NLKRSFTKQSISLASLPKIDD 348
N + ++ +E I+ L + +++ L +L + ++ + + +
Sbjct 294 NFRASDXXXVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPC 353
Query 349 FSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYL---SLSNSFTSLRTL--------- 396
Q LK LE+L++ +N L+ +YL + +++ SL+TL
Sbjct 354 LLSQHLKSLEYLDLSEN------------LMVEEYLKNSACEDAWPSLQTLILRQNHLAS 401
Query 397 ---TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWR 453
T ET ++L + L ++++KN + + W ++ L+L I +TG +
Sbjct 402 LEKTGETLLTLKN--LTNIDISKNSFHSM-PETCQWPEKMKYLNLSSTRI-HSVTGCIPK 457
Query 454 GLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV-DSSPSPFQPLRNLTILD 512
LE I ++ + +P L+ L + R L + D+S P L +L
Sbjct 458 TLE-ILDVSNNN------LNLFSLNLPQLKELYISRNKLMTLPDASLLPM-----LLVLK 505
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANP 551
+S N + ++ D + + L L+ ++W H NP
Sbjct 506 ISRNQLKSVPDGIFDRLTSLQ----------KIWLHTNP 534
>6nig_B B Toll-like receptor 2,Variable lymphocyte receptor B
Length=576
Score = 42.0 bits (97), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 23/186 (12%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
PSLQ L+LR+ L +++ + L+NLT +D+S N+ ++ + + EK++ L+L
Sbjct 387 PSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSM-PETCQWPEKMKYLNLSS 445
Query 540 NNLARLWKHANPGG-PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+ H+ G P L IL++ +N +L +LK + + N L
Sbjct 446 TRI-----HSVTGCIP-------KTLEILDVSNNNL----NLFSLNLPQLKELYISRNKL 489
Query 599 NTLP-ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWF 657
TLP AS+ + LK + +N + SV +F +L ++ + NP+DC+C I +
Sbjct 490 MTLPDASLLPMLLVLK---ISRNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYL 545
Query 658 VNWINE 663
W+N+
Sbjct 546 SRWLNK 551
Score = 41.2 bits (95), Expect = 0.057, Method: Compositional matrix adjust.
Identities = 112/519 (22%), Positives = 214/519 (41%), Gaps = 106/519 (20%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K L+L +N ++ +S+ C NL L L SN I I+ + F +L LDLS+N LS
Sbjct 54 VKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLS 113
Query 161 STK---------------LGTQVQLENLQELLLSNNKIQALKSEELDIFAN--------- 196
+ LG + L K+Q L+ +D F
Sbjct 114 NLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGL 173
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ------LGPSLTEKL-CLELANTS 249
+ L++LE+ ++ ++ + P +I + L L+ Q + +T + CLEL +T
Sbjct 174 TFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTD 233
Query 250 IRNLSLSNSQLSTTSNT----TFLGLKWTNLT-------------MLDLSYNN--LNVVG 290
+ S T++ TF +K T+ + +L+L +++ LN VG
Sbjct 234 LDTFHFSELSTGETNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLELEFDDCTLNGVG 293
Query 291 N-DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL-NLKRSFTKQSISLASLPKIDD 348
N + ++ +E I+ L + +++ L +L + ++ + + +
Sbjct 294 NFRASDXXXXIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTERVKRITVENSKVFLVPC 353
Query 349 FSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYL---SLSNSFTSLRTL--------- 396
Q LK LE+L++ +N L+ +YL + +++ SL+TL
Sbjct 354 LLSQHLKSLEYLDLSEN------------LMVEEYLKNSACEDAWPSLQTLILRQNHLAS 401
Query 397 ---TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTGQEWR 453
T ET ++L + L ++++KN + + W ++ L+L I +TG +
Sbjct 402 LEKTGETLLTLKN--LTNIDISKNSFHSM-PETCQWPEKMKYLNLSSTRI-HSVTGCIPK 457
Query 454 GLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV-DSSPSPFQPLRNLTILD 512
LE I ++ + +P L+ L + R L + D+S P L +L
Sbjct 458 TLE-ILDVSNNN------LNLFSLNLPQLKELYISRNKLMTLPDASLLPM-----LLVLK 505
Query 513 LSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANP 551
+S N + ++ D + + L L+ ++W H NP
Sbjct 506 ISRNQLKSVPDGIFDRLTSLQ----------KIWLHTNP 534
>6nig_C C Toll-like receptor 2,Variable lymphocyte receptor B
Length=576
Score = 42.0 bits (97), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 23/186 (12%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
PSLQ L+LR+ L +++ + L+NLT +D+S N+ ++ + + EK++ L+L
Sbjct 387 PSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSM-PETCQWPEKMKYLNLSS 445
Query 540 NNLARLWKHANPGG-PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+ H+ G P L IL++ +N +L +LK + + N L
Sbjct 446 TRI-----HSVTGCIP-------KTLEILDVSNNNL----NLFSLNLPQLKELYISRNKL 489
Query 599 NTLP-ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWF 657
TLP AS+ + LK + +N + SV +F +L ++ + NP+DC+C I +
Sbjct 490 MTLPDASLLPMLLVLK---ISRNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYL 545
Query 658 VNWINE 663
W+N+
Sbjct 546 SRWLNK 551
Score = 40.0 bits (92), Expect = 0.12, Method: Compositional matrix adjust.
Identities = 109/524 (21%), Positives = 210/524 (40%), Gaps = 116/524 (22%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K L+L +N ++ +S+ C NL L L SN I I+ + F +L LDLS+N LS
Sbjct 54 VKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLS 113
Query 161 STK---------------LGTQVQLENLQELLLSNNKIQALKSEELDIFAN--------- 196
+ LG + L K+Q L+ +D F
Sbjct 114 NLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGL 173
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ------LGPSLTEKL-CLELANTS 249
+ L++LE+ ++ ++ + P +I + L L+ Q + +T + CLEL +T
Sbjct 174 TFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTD 233
Query 250 IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFF----L 305
+ S+LST TN + ++ N+ + F + L L
Sbjct 234 LDTFHF--SELSTGE---------TNSLIKKFTFRNVKITDESLFQVMKLLNQISGLLEL 282
Query 306 EYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKID--------DFS--FQWLK 355
E+++ +L+G+ N R + R + ++ ++ D S + +
Sbjct 283 EFDDC------TLNGVGNFRASDNDRVIDPGKVETLTIRRLHIPRFYLFYDLSTLYSLTE 336
Query 356 CLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS---------------NSFTSLRTL---- 396
++ + +E++ + + + L +L+YL LS +++ SL+TL
Sbjct 337 RVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSLQTLILRQ 396
Query 397 --------TNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELT 448
T ET ++L + L ++++KN + + W ++ L+L I +T
Sbjct 397 NHLASLEKTGETLLTLKN--LTNIDISKNSFHSM-PETCQWPEKMKYLNLSSTRI-HSVT 452
Query 449 GQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNV-DSSPSPFQPLRN 507
G + LE I ++ + +P L+ L + R L + D+S P
Sbjct 453 GCIPKTLE-ILDVSNNN------LNLFSLNLPQLKELYISRNKLMTLPDASLLPM----- 500
Query 508 LTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANP 551
L +L +S N + ++ D + + L L+ ++W H NP
Sbjct 501 LLVLKISRNQLKSVPDGIFDRLTSLQ----------KIWLHTNP 534
>6nig_A A Toll-like receptor 2,Variable lymphocyte receptor B
Length=576
Score = 42.0 bits (97), Expect = 0.027, Method: Compositional matrix adjust.
Identities = 51/186 (27%), Positives = 92/186 (49%), Gaps = 23/186 (12%)
Query 480 PSLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQH 539
PSLQ L+LR+ L +++ + L+NLT +D+S N+ ++ + + EK++ L+L
Sbjct 387 PSLQTLILRQNHLASLEKTGETLLTLKNLTNIDISKNSFHSM-PETCQWPEKMKYLNLSS 445
Query 540 NNLARLWKHANPGG-PIYFLKGLSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNL 598
+ H+ G P L IL++ +N +L +LK + + N L
Sbjct 446 TRI-----HSVTGCIP-------KTLEILDVSNNNL----NLFSLNLPQLKELYISRNKL 489
Query 599 NTLP-ASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWF 657
TLP AS+ + LK + +N + SV +F +L ++ + NP+DC+C I +
Sbjct 490 MTLPDASLLPMLLVLK---ISRNQLKSVPDGIFD-RLTSLQKIWLHTNPWDCSCPRIDYL 545
Query 658 VNWINE 663
W+N+
Sbjct 546 SRWLNK 551
Score = 39.7 bits (91), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 49/193 (25%), Positives = 83/193 (43%), Gaps = 33/193 (17%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
+K L+L +N ++ +S+ C NL L L SN I I+ + F +L LDLS+N LS
Sbjct 54 VKSLDLSNNRITYISNSDLQRCVNLQALVLTSNGINTIEEDSFSSLGSLEHLDLSYNYLS 113
Query 161 STK---------------LGTQVQLENLQELLLSNNKIQALKSEELDIFAN--------- 196
+ LG + L K+Q L+ +D F
Sbjct 114 NLSSSWFKPLSSLTFLNLLGNPYKTLGETSLFSHLTKLQILRVGNMDTFTKIQRKDFAGL 173
Query 197 SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ------LGPSLTEKL-CLELANTS 249
+ L++LE+ ++ ++ + P +I + L L+ Q + +T + CLEL +T
Sbjct 174 TFLEELEIDASDLQSYEPKSLKSIQNVSHLILHMKQHILLLEIFVDVTSSVECLELRDTD 233
Query 250 IRNLSLSNSQLST 262
+ S+LST
Sbjct 234 LDTFHF--SELST 244
>5xjx_B K LRR receptor-like serine/threonine-protein kinase ERL1
Length=556
Score = 42.0 bits (97), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 120/470 (26%), Positives = 189/470 (40%), Gaps = 91/470 (19%)
Query 159 LSSTKLGTQV-----QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LSS LG ++ L NLQ + L NK+ +E+ A SL L+LS N +
Sbjct 55 LSSLNLGGEISPAIGDLRNLQSIDLQGNKLAGQIPDEIGNCA--SLVYLDLSENLLYGDI 112
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLC-------LELA--------------NTSIRN 252
P + +L L L N QL + L L+LA N ++
Sbjct 113 PFSISKLKQLETLNLKNNQLTGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQY 172
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
L L + L+ T ++ + T L D+ NNL +S + + YN I
Sbjct 173 LGLRGNMLTGTLSSDMC--QLTGLWYFDVRGNNLTGTIPESIGNCTSFQILDISYNQITG 230
Query 313 LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND----IP 368
+++ G V L+L+ + I P++ ++ L L++ DN+ IP
Sbjct 231 EIPYNI-GFLQVATLSLQGNRLTGRI-----PEV----IGLMQALAVLDLSDNELVGPIP 280
Query 369 GIKSNM-FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I N+ FTG + L L+ S L N S L L L NK+
Sbjct 281 PILGNLSFTGKLYLHGNMLTGPIPS--ELGN-------MSRLSYLQLNDNKL-------- 323
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+G + E+G+ LE +FE+ L+ N+ + ++ + +L + +
Sbjct 324 --VGTIPP------ELGK---------LEQLFELNLANNRLVGPIPSNISSCAALNQFNV 366
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
L S P F+ L +LT L+LS+NN L + L+ LDL NN +
Sbjct 367 HGNLLSG--SIPLAFRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLSGNNFS---- 420
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLN 596
G L L HL ILNL N ++P E F +L +++ID+ N
Sbjct 421 ----GSIPLTLGDLEHLLILNLSRNHLSGQLPAE-FGNLRSIQMIDVSFN 465
Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 106/415 (26%), Positives = 163/415 (39%), Gaps = 47/415 (11%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ ++L N+L + L LD+ N + P KL L+ LNL++N+L
Sbjct 73 NLQSIDLQGNKLAGQIPDEIGNCASLVYLDLSENLLYGDIPFSISKLKQLETLNLKNNQL 132
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ T NL L L N + + + L L L N L+ T QL
Sbjct 133 TGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQYLGLRGNMLTGTLSSDMCQLT 192
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIG--RLFGLFLN 229
L + N + E I +S + L++S NQI P + IG ++ L L
Sbjct 193 GLWYFDVRGNNLTGTIPES--IGNCTSFQILDISYNQITGEIP---YNIGFLQVATLSLQ 247
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQL-----STTSNTTFLGLKWTNLTMLD---- 280
+L + E + L A + L LS+++L N +F G + + ML
Sbjct 248 GNRLTGRIPEVIGLMQA---LAVLDLSDNELVGPIPPILGNLSFTGKLYLHGNMLTGPIP 304
Query 281 --------LSYNNLN---VVGN--DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
LSY LN +VG L QL L N + ++ +
Sbjct 305 SELGNMSRLSYLQLNDNKLVGTIPPELGKLEQLFELNLANNRLVGPIPSNISSCAALNQF 364
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
N+ + SI LA F+ L L +LN+ N+ G +INL L LS
Sbjct 365 NVHGNLLSGSIPLA---------FRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLS 415
Query 388 -NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
N+F+ L T L H L ILNL++N +S F L ++++D+ N
Sbjct 416 GNNFSGSIPL---TLGDLEH--LLILNLSRNHLSGQLPAEFGNLRSIQMIDVSFN 465
>5xjx_J I LRR receptor-like serine/threonine-protein kinase ERL1
Length=556
Score = 42.0 bits (97), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 120/470 (26%), Positives = 189/470 (40%), Gaps = 91/470 (19%)
Query 159 LSSTKLGTQV-----QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LSS LG ++ L NLQ + L NK+ +E+ A SL L+LS N +
Sbjct 55 LSSLNLGGEISPAIGDLRNLQSIDLQGNKLAGQIPDEIGNCA--SLVYLDLSENLLYGDI 112
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLC-------LELA--------------NTSIRN 252
P + +L L L N QL + L L+LA N ++
Sbjct 113 PFSISKLKQLETLNLKNNQLTGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQY 172
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
L L + L+ T ++ + T L D+ NNL +S + + YN I
Sbjct 173 LGLRGNMLTGTLSSDMC--QLTGLWYFDVRGNNLTGTIPESIGNCTSFQILDISYNQITG 230
Query 313 LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND----IP 368
+++ G V L+L+ + I P++ ++ L L++ DN+ IP
Sbjct 231 EIPYNI-GFLQVATLSLQGNRLTGRI-----PEV----IGLMQALAVLDLSDNELVGPIP 280
Query 369 GIKSNM-FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I N+ FTG + L L+ S L N S L L L NK+
Sbjct 281 PILGNLSFTGKLYLHGNMLTGPIPS--ELGN-------MSRLSYLQLNDNKL-------- 323
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+G + E+G+ LE +FE+ L+ N+ + ++ + +L + +
Sbjct 324 --VGTIPP------ELGK---------LEQLFELNLANNRLVGPIPSNISSCAALNQFNV 366
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
L S P F+ L +LT L+LS+NN L + L+ LDL NN +
Sbjct 367 HGNLLSG--SIPLAFRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLSGNNFS---- 420
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLN 596
G L L HL ILNL N ++P E F +L +++ID+ N
Sbjct 421 ----GSIPLTLGDLEHLLILNLSRNHLSGQLPAE-FGNLRSIQMIDVSFN 465
Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 106/415 (26%), Positives = 163/415 (39%), Gaps = 47/415 (11%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ ++L N+L + L LD+ N + P KL L+ LNL++N+L
Sbjct 73 NLQSIDLQGNKLAGQIPDEIGNCASLVYLDLSENLLYGDIPFSISKLKQLETLNLKNNQL 132
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ T NL L L N + + + L L L N L+ T QL
Sbjct 133 TGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQYLGLRGNMLTGTLSSDMCQLT 192
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIG--RLFGLFLN 229
L + N + E I +S + L++S NQI P + IG ++ L L
Sbjct 193 GLWYFDVRGNNLTGTIPES--IGNCTSFQILDISYNQITGEIP---YNIGFLQVATLSLQ 247
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQL-----STTSNTTFLGLKWTNLTMLD---- 280
+L + E + L A + L LS+++L N +F G + + ML
Sbjct 248 GNRLTGRIPEVIGLMQA---LAVLDLSDNELVGPIPPILGNLSFTGKLYLHGNMLTGPIP 304
Query 281 --------LSYNNLN---VVGN--DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
LSY LN +VG L QL L N + ++ +
Sbjct 305 SELGNMSRLSYLQLNDNKLVGTIPPELGKLEQLFELNLANNRLVGPIPSNISSCAALNQF 364
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
N+ + SI LA F+ L L +LN+ N+ G +INL L LS
Sbjct 365 NVHGNLLSGSIPLA---------FRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLS 415
Query 388 -NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
N+F+ L T L H L ILNL++N +S F L ++++D+ N
Sbjct 416 GNNFSGSIPL---TLGDLEH--LLILNLSRNHLSGQLPAEFGNLRSIQMIDVSFN 465
>5xjx_L E LRR receptor-like serine/threonine-protein kinase ERL1
Length=556
Score = 42.0 bits (97), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 120/470 (26%), Positives = 189/470 (40%), Gaps = 91/470 (19%)
Query 159 LSSTKLGTQV-----QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LSS LG ++ L NLQ + L NK+ +E+ A SL L+LS N +
Sbjct 55 LSSLNLGGEISPAIGDLRNLQSIDLQGNKLAGQIPDEIGNCA--SLVYLDLSENLLYGDI 112
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLC-------LELA--------------NTSIRN 252
P + +L L L N QL + L L+LA N ++
Sbjct 113 PFSISKLKQLETLNLKNNQLTGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQY 172
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
L L + L+ T ++ + T L D+ NNL +S + + YN I
Sbjct 173 LGLRGNMLTGTLSSDMC--QLTGLWYFDVRGNNLTGTIPESIGNCTSFQILDISYNQITG 230
Query 313 LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND----IP 368
+++ G V L+L+ + I P++ ++ L L++ DN+ IP
Sbjct 231 EIPYNI-GFLQVATLSLQGNRLTGRI-----PEV----IGLMQALAVLDLSDNELVGPIP 280
Query 369 GIKSNM-FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I N+ FTG + L L+ S L N S L L L NK+
Sbjct 281 PILGNLSFTGKLYLHGNMLTGPIPS--ELGN-------MSRLSYLQLNDNKL-------- 323
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+G + E+G+ LE +FE+ L+ N+ + ++ + +L + +
Sbjct 324 --VGTIPP------ELGK---------LEQLFELNLANNRLVGPIPSNISSCAALNQFNV 366
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
L S P F+ L +LT L+LS+NN L + L+ LDL NN +
Sbjct 367 HGNLLSG--SIPLAFRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLSGNNFS---- 420
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLN 596
G L L HL ILNL N ++P E F +L +++ID+ N
Sbjct 421 ----GSIPLTLGDLEHLLILNLSRNHLSGQLPAE-FGNLRSIQMIDVSFN 465
Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 106/415 (26%), Positives = 163/415 (39%), Gaps = 47/415 (11%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ ++L N+L + L LD+ N + P KL L+ LNL++N+L
Sbjct 73 NLQSIDLQGNKLAGQIPDEIGNCASLVYLDLSENLLYGDIPFSISKLKQLETLNLKNNQL 132
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ T NL L L N + + + L L L N L+ T QL
Sbjct 133 TGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQYLGLRGNMLTGTLSSDMCQLT 192
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIG--RLFGLFLN 229
L + N + E I +S + L++S NQI P + IG ++ L L
Sbjct 193 GLWYFDVRGNNLTGTIPES--IGNCTSFQILDISYNQITGEIP---YNIGFLQVATLSLQ 247
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQL-----STTSNTTFLGLKWTNLTMLD---- 280
+L + E + L A + L LS+++L N +F G + + ML
Sbjct 248 GNRLTGRIPEVIGLMQA---LAVLDLSDNELVGPIPPILGNLSFTGKLYLHGNMLTGPIP 304
Query 281 --------LSYNNLN---VVGN--DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
LSY LN +VG L QL L N + ++ +
Sbjct 305 SELGNMSRLSYLQLNDNKLVGTIPPELGKLEQLFELNLANNRLVGPIPSNISSCAALNQF 364
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
N+ + SI LA F+ L L +LN+ N+ G +INL L LS
Sbjct 365 NVHGNLLSGSIPLA---------FRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLS 415
Query 388 -NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
N+F+ L T L H L ILNL++N +S F L ++++D+ N
Sbjct 416 GNNFSGSIPL---TLGDLEH--LLILNLSRNHLSGQLPAEFGNLRSIQMIDVSFN 465
>5xjx_K B LRR receptor-like serine/threonine-protein kinase ERL1
Length=556
Score = 42.0 bits (97), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 120/470 (26%), Positives = 189/470 (40%), Gaps = 91/470 (19%)
Query 159 LSSTKLGTQV-----QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LSS LG ++ L NLQ + L NK+ +E+ A SL L+LS N +
Sbjct 55 LSSLNLGGEISPAIGDLRNLQSIDLQGNKLAGQIPDEIGNCA--SLVYLDLSENLLYGDI 112
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLC-------LELA--------------NTSIRN 252
P + +L L L N QL + L L+LA N ++
Sbjct 113 PFSISKLKQLETLNLKNNQLTGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQY 172
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
L L + L+ T ++ + T L D+ NNL +S + + YN I
Sbjct 173 LGLRGNMLTGTLSSDMC--QLTGLWYFDVRGNNLTGTIPESIGNCTSFQILDISYNQITG 230
Query 313 LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND----IP 368
+++ G V L+L+ + I P++ ++ L L++ DN+ IP
Sbjct 231 EIPYNI-GFLQVATLSLQGNRLTGRI-----PEV----IGLMQALAVLDLSDNELVGPIP 280
Query 369 GIKSNM-FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I N+ FTG + L L+ S L N S L L L NK+
Sbjct 281 PILGNLSFTGKLYLHGNMLTGPIPS--ELGN-------MSRLSYLQLNDNKL-------- 323
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+G + E+G+ LE +FE+ L+ N+ + ++ + +L + +
Sbjct 324 --VGTIPP------ELGK---------LEQLFELNLANNRLVGPIPSNISSCAALNQFNV 366
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
L S P F+ L +LT L+LS+NN L + L+ LDL NN +
Sbjct 367 HGNLLSG--SIPLAFRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLSGNNFS---- 420
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLN 596
G L L HL ILNL N ++P E F +L +++ID+ N
Sbjct 421 ----GSIPLTLGDLEHLLILNLSRNHLSGQLPAE-FGNLRSIQMIDVSFN 465
Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 106/415 (26%), Positives = 163/415 (39%), Gaps = 47/415 (11%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ ++L N+L + L LD+ N + P KL L+ LNL++N+L
Sbjct 73 NLQSIDLQGNKLAGQIPDEIGNCASLVYLDLSENLLYGDIPFSISKLKQLETLNLKNNQL 132
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ T NL L L N + + + L L L N L+ T QL
Sbjct 133 TGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQYLGLRGNMLTGTLSSDMCQLT 192
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIG--RLFGLFLN 229
L + N + E I +S + L++S NQI P + IG ++ L L
Sbjct 193 GLWYFDVRGNNLTGTIPES--IGNCTSFQILDISYNQITGEIP---YNIGFLQVATLSLQ 247
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQL-----STTSNTTFLGLKWTNLTMLD---- 280
+L + E + L A + L LS+++L N +F G + + ML
Sbjct 248 GNRLTGRIPEVIGLMQA---LAVLDLSDNELVGPIPPILGNLSFTGKLYLHGNMLTGPIP 304
Query 281 --------LSYNNLN---VVGN--DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
LSY LN +VG L QL L N + ++ +
Sbjct 305 SELGNMSRLSYLQLNDNKLVGTIPPELGKLEQLFELNLANNRLVGPIPSNISSCAALNQF 364
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
N+ + SI LA F+ L L +LN+ N+ G +INL L LS
Sbjct 365 NVHGNLLSGSIPLA---------FRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLS 415
Query 388 -NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
N+F+ L T L H L ILNL++N +S F L ++++D+ N
Sbjct 416 GNNFSGSIPL---TLGDLEH--LLILNLSRNHLSGQLPAEFGNLRSIQMIDVSFN 465
>5xjx_I A LRR receptor-like serine/threonine-protein kinase ERL1
Length=556
Score = 42.0 bits (97), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 120/470 (26%), Positives = 189/470 (40%), Gaps = 91/470 (19%)
Query 159 LSSTKLGTQV-----QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LSS LG ++ L NLQ + L NK+ +E+ A SL L+LS N +
Sbjct 55 LSSLNLGGEISPAIGDLRNLQSIDLQGNKLAGQIPDEIGNCA--SLVYLDLSENLLYGDI 112
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLC-------LELA--------------NTSIRN 252
P + +L L L N QL + L L+LA N ++
Sbjct 113 PFSISKLKQLETLNLKNNQLTGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQY 172
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
L L + L+ T ++ + T L D+ NNL +S + + YN I
Sbjct 173 LGLRGNMLTGTLSSDMC--QLTGLWYFDVRGNNLTGTIPESIGNCTSFQILDISYNQITG 230
Query 313 LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND----IP 368
+++ G V L+L+ + I P++ ++ L L++ DN+ IP
Sbjct 231 EIPYNI-GFLQVATLSLQGNRLTGRI-----PEV----IGLMQALAVLDLSDNELVGPIP 280
Query 369 GIKSNM-FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I N+ FTG + L L+ S L N S L L L NK+
Sbjct 281 PILGNLSFTGKLYLHGNMLTGPIPS--ELGN-------MSRLSYLQLNDNKL-------- 323
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+G + E+G+ LE +FE+ L+ N+ + ++ + +L + +
Sbjct 324 --VGTIPP------ELGK---------LEQLFELNLANNRLVGPIPSNISSCAALNQFNV 366
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
L S P F+ L +LT L+LS+NN L + L+ LDL NN +
Sbjct 367 HGNLLSG--SIPLAFRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLSGNNFS---- 420
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLN 596
G L L HL ILNL N ++P E F +L +++ID+ N
Sbjct 421 ----GSIPLTLGDLEHLLILNLSRNHLSGQLPAE-FGNLRSIQMIDVSFN 465
Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 106/415 (26%), Positives = 163/415 (39%), Gaps = 47/415 (11%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ ++L N+L + L LD+ N + P KL L+ LNL++N+L
Sbjct 73 NLQSIDLQGNKLAGQIPDEIGNCASLVYLDLSENLLYGDIPFSISKLKQLETLNLKNNQL 132
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ T NL L L N + + + L L L N L+ T QL
Sbjct 133 TGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQYLGLRGNMLTGTLSSDMCQLT 192
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIG--RLFGLFLN 229
L + N + E I +S + L++S NQI P + IG ++ L L
Sbjct 193 GLWYFDVRGNNLTGTIPES--IGNCTSFQILDISYNQITGEIP---YNIGFLQVATLSLQ 247
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQL-----STTSNTTFLGLKWTNLTMLD---- 280
+L + E + L A + L LS+++L N +F G + + ML
Sbjct 248 GNRLTGRIPEVIGLMQA---LAVLDLSDNELVGPIPPILGNLSFTGKLYLHGNMLTGPIP 304
Query 281 --------LSYNNLN---VVGN--DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
LSY LN +VG L QL L N + ++ +
Sbjct 305 SELGNMSRLSYLQLNDNKLVGTIPPELGKLEQLFELNLANNRLVGPIPSNISSCAALNQF 364
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
N+ + SI LA F+ L L +LN+ N+ G +INL L LS
Sbjct 365 NVHGNLLSGSIPLA---------FRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLS 415
Query 388 -NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
N+F+ L T L H L ILNL++N +S F L ++++D+ N
Sbjct 416 GNNFSGSIPL---TLGDLEH--LLILNLSRNHLSGQLPAEFGNLRSIQMIDVSFN 465
>5xjx_H G LRR receptor-like serine/threonine-protein kinase ERL1
Length=556
Score = 42.0 bits (97), Expect = 0.029, Method: Compositional matrix adjust.
Identities = 120/470 (26%), Positives = 189/470 (40%), Gaps = 91/470 (19%)
Query 159 LSSTKLGTQV-----QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LSS LG ++ L NLQ + L NK+ +E+ A SL L+LS N +
Sbjct 55 LSSLNLGGEISPAIGDLRNLQSIDLQGNKLAGQIPDEIGNCA--SLVYLDLSENLLYGDI 112
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLC-------LELA--------------NTSIRN 252
P + +L L L N QL + L L+LA N ++
Sbjct 113 PFSISKLKQLETLNLKNNQLTGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQY 172
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
L L + L+ T ++ + T L D+ NNL +S + + YN I
Sbjct 173 LGLRGNMLTGTLSSDMC--QLTGLWYFDVRGNNLTGTIPESIGNCTSFQILDISYNQITG 230
Query 313 LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND----IP 368
+++ G V L+L+ + I P++ ++ L L++ DN+ IP
Sbjct 231 EIPYNI-GFLQVATLSLQGNRLTGRI-----PEV----IGLMQALAVLDLSDNELVGPIP 280
Query 369 GIKSNM-FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I N+ FTG + L L+ S L N S L L L NK+
Sbjct 281 PILGNLSFTGKLYLHGNMLTGPIPS--ELGN-------MSRLSYLQLNDNKL-------- 323
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+G + E+G+ LE +FE+ L+ N+ + ++ + +L + +
Sbjct 324 --VGTIPP------ELGK---------LEQLFELNLANNRLVGPIPSNISSCAALNQFNV 366
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
L S P F+ L +LT L+LS+NN L + L+ LDL NN +
Sbjct 367 HGNLLSG--SIPLAFRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLSGNNFS---- 420
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLN 596
G L L HL ILNL N ++P E F +L +++ID+ N
Sbjct 421 ----GSIPLTLGDLEHLLILNLSRNHLSGQLPAE-FGNLRSIQMIDVSFN 465
Score = 40.0 bits (92), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 106/415 (26%), Positives = 163/415 (39%), Gaps = 47/415 (11%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ ++L N+L + L LD+ N + P KL L+ LNL++N+L
Sbjct 73 NLQSIDLQGNKLAGQIPDEIGNCASLVYLDLSENLLYGDIPFSISKLKQLETLNLKNNQL 132
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ T NL L L N + + + L L L N L+ T QL
Sbjct 133 TGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQYLGLRGNMLTGTLSSDMCQLT 192
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIG--RLFGLFLN 229
L + N + E I +S + L++S NQI P + IG ++ L L
Sbjct 193 GLWYFDVRGNNLTGTIPES--IGNCTSFQILDISYNQITGEIP---YNIGFLQVATLSLQ 247
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQL-----STTSNTTFLGLKWTNLTMLD---- 280
+L + E + L A + L LS+++L N +F G + + ML
Sbjct 248 GNRLTGRIPEVIGLMQA---LAVLDLSDNELVGPIPPILGNLSFTGKLYLHGNMLTGPIP 304
Query 281 --------LSYNNLN---VVGN--DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
LSY LN +VG L QL L N + ++ +
Sbjct 305 SELGNMSRLSYLQLNDNKLVGTIPPELGKLEQLFELNLANNRLVGPIPSNISSCAALNQF 364
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
N+ + SI LA F+ L L +LN+ N+ G +INL L LS
Sbjct 365 NVHGNLLSGSIPLA---------FRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLS 415
Query 388 -NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
N+F+ L T L H L ILNL++N +S F L ++++D+ N
Sbjct 416 GNNFSGSIPL---TLGDLEH--LLILNLSRNHLSGQLPAEFGNLRSIQMIDVSFN 465
>5y9w_A B Pollen receptor-like kinase 6
Length=242
Score = 41.2 bits (95), Expect = 0.031, Method: Compositional matrix adjust.
Identities = 45/159 (28%), Positives = 64/159 (40%), Gaps = 8/159 (5%)
Query 4 TLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQL 63
T PC W FG+ C T + S DLP N+ + L +N L
Sbjct 29 TDPCSGKW-----FGIYCQKGLTVSGIHVTRLGLSGTITVDDLKDLP-NLKTIRLDNNLL 82
Query 64 RRLPAANFTRYSQLTSLDVGFNTIS-KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFC 122
P +F + L SL + N+ S ++ + + + LK L L HN+ +
Sbjct 83 SG-PLPHFFKLRGLKSLMLSNNSFSGEIRDDFFKDMSKLKRLFLDHNKFEGSIPSSITQL 141
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L ELH+ SN++ F KNL LDLS N L
Sbjct 142 PQLEELHMQSNNLTGEIPPEFGSMKNLKVLDLSTNSLDG 180
Score = 33.9 bits (76), Expect = 7.1, Method: Compositional matrix adjust.
Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLM 486
F L L+ L L N E+ ++ + + ++L +NK+ +S +P L+ L
Sbjct 89 FFKLRGLKSLMLSNNSFSGEIRDDFFKDMSKLKRLFLDHNKFEGSIPSSITQLPQLEELH 148
Query 487 LRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI 521
++ L P F ++NL +LDLS N++ I
Sbjct 149 MQSNNL--TGEIPPEFGSMKNLKVLDLSTNSLDGI 181
Score = 33.5 bits (75), Expect = 8.6, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 53/120 (44%), Gaps = 4/120 (3%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ-KIKNNPFVKQKNLITLDL 154
+ LP LK + L +N LS F L L L +NS +I+++ F L L L
Sbjct 67 KDLPNLKTIRLDNNLLSGPLPHFFKL-RGLKSLMLSNNSFSGEIRDDFFKDMSKLKRLFL 125
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
HN + + QL L+EL + +N + E N LK L+LS+N + P
Sbjct 126 DHNKFEGSIPSSITQLPQLEELHMQSNNLTGEIPPEFGSMKN--LKVLDLSTNSLDGIVP 183
>5yah_A B Pollen receptor-like kinase 6
Length=242
Score = 40.8 bits (94), Expect = 0.035, Method: Compositional matrix adjust.
Identities = 45/159 (28%), Positives = 64/159 (40%), Gaps = 8/159 (5%)
Query 4 TLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQL 63
T PC W FG+ C T + S DLP N+ + L +N L
Sbjct 29 TDPCSGKW-----FGIYCQKGLTVSGIHVTRLGLSGTITVDDLKDLP-NLKTIRLDNNLL 82
Query 64 RRLPAANFTRYSQLTSLDVGFNTIS-KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFC 122
P +F + L SL + N+ S ++ + + + LK L L HN+ +
Sbjct 83 SG-PLPHFFKLRGLKSLMLSNNSFSGEIRDDFFKDMSKLKRLFLDHNKFEGSIPSSITQL 141
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L ELH+ SN++ F KNL LDLS N L
Sbjct 142 PQLEELHMQSNNLTGEIPPEFGSMKNLKVLDLSTNSLDG 180
Score = 33.9 bits (76), Expect = 7.2, Method: Compositional matrix adjust.
Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLM 486
F L L+ L L N E+ ++ + + ++L +NK+ +S +P L+ L
Sbjct 89 FFKLRGLKSLMLSNNSFSGEIRDDFFKDMSKLKRLFLDHNKFEGSIPSSITQLPQLEELH 148
Query 487 LRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI 521
++ L P F ++NL +LDLS N++ I
Sbjct 149 MQSNNL--TGEIPPEFGSMKNLKVLDLSTNSLDGI 181
Score = 33.5 bits (75), Expect = 9.1, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 53/120 (44%), Gaps = 4/120 (3%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ-KIKNNPFVKQKNLITLDL 154
+ LP LK + L +N LS F L L L +NS +I+++ F L L L
Sbjct 67 KDLPNLKTIRLDNNLLSGPLPHFFKL-RGLKSLMLSNNSFSGEIRDDFFKDMSKLKRLFL 125
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
HN + + QL L+EL + +N + E N LK L+LS+N + P
Sbjct 126 DHNKFEGSIPSSITQLPQLEELHMQSNNLTGEIPPEFGSMKN--LKVLDLSTNSLDGIVP 183
>5y9w_C A Pollen receptor-like kinase 6
Length=242
Score = 40.8 bits (94), Expect = 0.040, Method: Compositional matrix adjust.
Identities = 45/159 (28%), Positives = 64/159 (40%), Gaps = 8/159 (5%)
Query 4 TLPCIYFWGGLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQL 63
T PC W FG+ C T + S DLP N+ + L +N L
Sbjct 29 TDPCSGKW-----FGIYCQKGLTVSGIHVTRLGLSGTITVDDLKDLP-NLKTIRLDNNLL 82
Query 64 RRLPAANFTRYSQLTSLDVGFNTIS-KLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFC 122
P +F + L SL + N+ S ++ + + + LK L L HN+ +
Sbjct 83 SG-PLPHFFKLRGLKSLMLSNNSFSGEIRDDFFKDMSKLKRLFLDHNKFEGSIPSSITQL 141
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L ELH+ SN++ F KNL LDLS N L
Sbjct 142 PQLEELHMQSNNLTGEIPPEFGSMKNLKVLDLSTNSLDG 180
Score = 33.5 bits (75), Expect = 7.4, Method: Compositional matrix adjust.
Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 2/95 (2%)
Query 427 FSWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLM 486
F L L+ L L N E+ ++ + + ++L +NK+ +S +P L+ L
Sbjct 89 FFKLRGLKSLMLSNNSFSGEIRDDFFKDMSKLKRLFLDHNKFEGSIPSSITQLPQLEELH 148
Query 487 LRRVALKNVDSSPSPFQPLRNLTILDLSNNNIANI 521
++ L P F ++NL +LDLS N++ I
Sbjct 149 MQSNNL--TGEIPPEFGSMKNLKVLDLSTNSLDGI 181
Score = 33.1 bits (74), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 36/120 (30%), Positives = 53/120 (44%), Gaps = 4/120 (3%)
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQ-KIKNNPFVKQKNLITLDL 154
+ LP LK + L +N LS F L L L +NS +I+++ F L L L
Sbjct 67 KDLPNLKTIRLDNNLLSGPLPHFFKL-RGLKSLMLSNNSFSGEIRDDFFKDMSKLKRLFL 125
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
HN + + QL L+EL + +N + E N LK L+LS+N + P
Sbjct 126 DHNKFEGSIPSSITQLPQLEELHMQSNNLTGEIPPEFGSMKN--LKVLDLSTNSLDGIVP 183
>7fch_A A Interleukin-18 receptor accessory protein
Length=166
Score = 39.7 bits (91), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 23/64 (36%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Query 787 CLEERDFEAGVFELEAIVNSIKRSRKIIFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDS 846
CL ERD G E IV+ IKRSR+ IF+++ + + P F++ AV A++
Sbjct 47 CLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYVNGP--SIFELQAAVNLALDDQTLK 104
Query 847 IILV 850
+IL+
Sbjct 105 LILI 108
>7fch_B B Interleukin-18 receptor accessory protein
Length=166
Score = 39.7 bits (91), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 23/64 (36%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Query 787 CLEERDFEAGVFELEAIVNSIKRSRKIIFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDS 846
CL ERD G E IV+ IKRSR+ IF+++ + + P F++ AV A++
Sbjct 47 CLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYVNGP--SIFELQAAVNLALDDQTLK 104
Query 847 IILV 850
+IL+
Sbjct 105 LILI 108
>7fch_D D Interleukin-18 receptor accessory protein
Length=166
Score = 39.7 bits (91), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 23/64 (36%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Query 787 CLEERDFEAGVFELEAIVNSIKRSRKIIFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDS 846
CL ERD G E IV+ IKRSR+ IF+++ + + P F++ AV A++
Sbjct 47 CLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYVNGP--SIFELQAAVNLALDDQTLK 104
Query 847 IILV 850
+IL+
Sbjct 105 LILI 108
>7fch_C C Interleukin-18 receptor accessory protein
Length=166
Score = 39.7 bits (91), Expect = 0.045, Method: Compositional matrix adjust.
Identities = 23/64 (36%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Query 787 CLEERDFEAGVFELEAIVNSIKRSRKIIFVITHHLLKDPLCKRFKVHHAVQQAIEQNLDS 846
CL ERD G E IV+ IKRSR+ IF+++ + + P F++ AV A++
Sbjct 47 CLLERDVAPGGVYAEDIVSIIKRSRRGIFILSPNYVNGP--SIFELQAAVNLALDDQTLK 104
Query 847 IILV 850
+IL+
Sbjct 105 LILI 108
>5xkj_E B LRR receptor-like serine/threonine-protein kinase ERL1
Length=555
Score = 40.8 bits (94), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 120/470 (26%), Positives = 189/470 (40%), Gaps = 91/470 (19%)
Query 159 LSSTKLGTQV-----QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LSS LG ++ L NLQ + L NK+ +E+ A SL L+LS N +
Sbjct 55 LSSLNLGGEISPAIGDLRNLQSIDLQGNKLAGQIPDEIGNCA--SLVYLDLSENLLYGDI 112
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLC-------LELA--------------NTSIRN 252
P + +L L L N QL + L L+LA N ++
Sbjct 113 PFSISKLKQLETLNLKNNQLTGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQY 172
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
L L + L+ T ++ + T L D+ NNL +S + + YN I
Sbjct 173 LGLRGNMLTGTLSSDMC--QLTGLWYFDVRGNNLTGTIPESIGNCTSFQILDISYNQITG 230
Query 313 LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND----IP 368
+++ G V L+L+ + I P++ ++ L L++ DN+ IP
Sbjct 231 EIPYNI-GFLQVATLSLQGNRLTGRI-----PEV----IGLMQALAVLDLSDNELVGPIP 280
Query 369 GIKSNM-FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I N+ FTG + L L+ S L N S L L L NK+
Sbjct 281 PILGNLSFTGKLYLHGNMLTGPIPS--ELGN-------MSRLSYLQLNDNKL-------- 323
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+G + E+G+ LE +FE+ L+ N+ + ++ + +L + +
Sbjct 324 --VGTIPP------ELGK---------LEQLFELNLANNRLVGPIPSNISSCAALNQFNV 366
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
L S P F+ L +LT L+LS+NN L + L+ LDL NN +
Sbjct 367 HGNLLSG--SIPLAFRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLSGNNFS---- 420
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLN 596
G L L HL ILNL N ++P E F +L +++ID+ N
Sbjct 421 ----GSIPLTLGDLEHLLILNLSRNHLSGQLPAE-FGNLRSIQMIDVSFN 465
Score = 38.9 bits (89), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 106/415 (26%), Positives = 163/415 (39%), Gaps = 47/415 (11%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ ++L N+L + L LD+ N + P KL L+ LNL++N+L
Sbjct 73 NLQSIDLQGNKLAGQIPDEIGNCASLVYLDLSENLLYGDIPFSISKLKQLETLNLKNNQL 132
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ T NL L L N + + + L L L N L+ T QL
Sbjct 133 TGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQYLGLRGNMLTGTLSSDMCQLT 192
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIG--RLFGLFLN 229
L + N + E I +S + L++S NQI P + IG ++ L L
Sbjct 193 GLWYFDVRGNNLTGTIPES--IGNCTSFQILDISYNQITGEIP---YNIGFLQVATLSLQ 247
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQL-----STTSNTTFLGLKWTNLTMLD---- 280
+L + E + L A + L LS+++L N +F G + + ML
Sbjct 248 GNRLTGRIPEVIGLMQA---LAVLDLSDNELVGPIPPILGNLSFTGKLYLHGNMLTGPIP 304
Query 281 --------LSYNNLN---VVGN--DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
LSY LN +VG L QL L N + ++ +
Sbjct 305 SELGNMSRLSYLQLNDNKLVGTIPPELGKLEQLFELNLANNRLVGPIPSNISSCAALNQF 364
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
N+ + SI LA F+ L L +LN+ N+ G +INL L LS
Sbjct 365 NVHGNLLSGSIPLA---------FRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLS 415
Query 388 -NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
N+F+ L T L H L ILNL++N +S F L ++++D+ N
Sbjct 416 GNNFSGSIPL---TLGDLEH--LLILNLSRNHLSGQLPAEFGNLRSIQMIDVSFN 465
>5xkj_C A LRR receptor-like serine/threonine-protein kinase ERL1
Length=555
Score = 40.8 bits (94), Expect = 0.061, Method: Compositional matrix adjust.
Identities = 120/470 (26%), Positives = 189/470 (40%), Gaps = 91/470 (19%)
Query 159 LSSTKLGTQV-----QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LSS LG ++ L NLQ + L NK+ +E+ A SL L+LS N +
Sbjct 55 LSSLNLGGEISPAIGDLRNLQSIDLQGNKLAGQIPDEIGNCA--SLVYLDLSENLLYGDI 112
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLC-------LELA--------------NTSIRN 252
P + +L L L N QL + L L+LA N ++
Sbjct 113 PFSISKLKQLETLNLKNNQLTGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQY 172
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
L L + L+ T ++ + T L D+ NNL +S + + YN I
Sbjct 173 LGLRGNMLTGTLSSDMC--QLTGLWYFDVRGNNLTGTIPESIGNCTSFQILDISYNQITG 230
Query 313 LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND----IP 368
+++ G V L+L+ + I P++ ++ L L++ DN+ IP
Sbjct 231 EIPYNI-GFLQVATLSLQGNRLTGRI-----PEV----IGLMQALAVLDLSDNELVGPIP 280
Query 369 GIKSNM-FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I N+ FTG + L L+ S L N S L L L NK+
Sbjct 281 PILGNLSFTGKLYLHGNMLTGPIPS--ELGN-------MSRLSYLQLNDNKL-------- 323
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+G + E+G+ LE +FE+ L+ N+ + ++ + +L + +
Sbjct 324 --VGTIPP------ELGK---------LEQLFELNLANNRLVGPIPSNISSCAALNQFNV 366
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
L S P F+ L +LT L+LS+NN L + L+ LDL NN +
Sbjct 367 HGNLLSG--SIPLAFRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLSGNNFS---- 420
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLN 596
G L L HL ILNL N ++P E F +L +++ID+ N
Sbjct 421 ----GSIPLTLGDLEHLLILNLSRNHLSGQLPAE-FGNLRSIQMIDVSFN 465
Score = 38.9 bits (89), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 106/415 (26%), Positives = 163/415 (39%), Gaps = 47/415 (11%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ ++L N+L + L LD+ N + P KL L+ LNL++N+L
Sbjct 73 NLQSIDLQGNKLAGQIPDEIGNCASLVYLDLSENLLYGDIPFSISKLKQLETLNLKNNQL 132
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ T NL L L N + + + L L L N L+ T QL
Sbjct 133 TGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQYLGLRGNMLTGTLSSDMCQLT 192
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIG--RLFGLFLN 229
L + N + E I +S + L++S NQI P + IG ++ L L
Sbjct 193 GLWYFDVRGNNLTGTIPES--IGNCTSFQILDISYNQITGEIP---YNIGFLQVATLSLQ 247
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQL-----STTSNTTFLGLKWTNLTMLD---- 280
+L + E + L A + L LS+++L N +F G + + ML
Sbjct 248 GNRLTGRIPEVIGLMQA---LAVLDLSDNELVGPIPPILGNLSFTGKLYLHGNMLTGPIP 304
Query 281 --------LSYNNLN---VVGN--DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
LSY LN +VG L QL L N + ++ +
Sbjct 305 SELGNMSRLSYLQLNDNKLVGTIPPELGKLEQLFELNLANNRLVGPIPSNISSCAALNQF 364
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
N+ + SI LA F+ L L +LN+ N+ G +INL L LS
Sbjct 365 NVHGNLLSGSIPLA---------FRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLS 415
Query 388 -NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
N+F+ L T L H L ILNL++N +S F L ++++D+ N
Sbjct 416 GNNFSGSIPL---TLGDLEH--LLILNLSRNHLSGQLPAEFGNLRSIQMIDVSFN 465
>5xjo_F B LRR receptor-like serine/threonine-protein kinase ERL1
Length=539
Score = 40.8 bits (94), Expect = 0.067, Method: Compositional matrix adjust.
Identities = 120/470 (26%), Positives = 189/470 (40%), Gaps = 91/470 (19%)
Query 159 LSSTKLGTQV-----QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LSS LG ++ L NLQ + L NK+ +E+ A SL L+LS N +
Sbjct 51 LSSLNLGGEISPAIGDLRNLQSIDLQGNKLAGQIPDEIGNCA--SLVYLDLSENLLYGDI 108
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLC-------LELA--------------NTSIRN 252
P + +L L L N QL + L L+LA N ++
Sbjct 109 PFSISKLKQLETLNLKNNQLTGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQY 168
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
L L + L+ T ++ + T L D+ NNL +S + + YN I
Sbjct 169 LGLRGNMLTGTLSSDMC--QLTGLWYFDVRGNNLTGTIPESIGNCTSFQILDISYNQITG 226
Query 313 LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND----IP 368
+++ G V L+L+ + I P++ ++ L L++ DN+ IP
Sbjct 227 EIPYNI-GFLQVATLSLQGNRLTGRI-----PEV----IGLMQALAVLDLSDNELVGPIP 276
Query 369 GIKSNM-FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I N+ FTG + L L+ S L N S L L L NK+
Sbjct 277 PILGNLSFTGKLYLHGNMLTGPIPS--ELGN-------MSRLSYLQLNDNKL-------- 319
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+G + E+G+ LE +FE+ L+ N+ + ++ + +L + +
Sbjct 320 --VGTIPP------ELGK---------LEQLFELNLANNRLVGPIPSNISSCAALNQFNV 362
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
L S P F+ L +LT L+LS+NN L + L+ LDL NN +
Sbjct 363 HGNLLSG--SIPLAFRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLSGNNFS---- 416
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLN 596
G L L HL ILNL N ++P E F +L +++ID+ N
Sbjct 417 ----GSIPLTLGDLEHLLILNLSRNHLSGQLPAE-FGNLRSIQMIDVSFN 461
Score = 38.9 bits (89), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 106/415 (26%), Positives = 163/415 (39%), Gaps = 47/415 (11%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ ++L N+L + L LD+ N + P KL L+ LNL++N+L
Sbjct 69 NLQSIDLQGNKLAGQIPDEIGNCASLVYLDLSENLLYGDIPFSISKLKQLETLNLKNNQL 128
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ T NL L L N + + + L L L N L+ T QL
Sbjct 129 TGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQYLGLRGNMLTGTLSSDMCQLT 188
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIG--RLFGLFLN 229
L + N + E I +S + L++S NQI P + IG ++ L L
Sbjct 189 GLWYFDVRGNNLTGTIPES--IGNCTSFQILDISYNQITGEIP---YNIGFLQVATLSLQ 243
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQL-----STTSNTTFLGLKWTNLTMLD---- 280
+L + E + L A + L LS+++L N +F G + + ML
Sbjct 244 GNRLTGRIPEVIGLMQA---LAVLDLSDNELVGPIPPILGNLSFTGKLYLHGNMLTGPIP 300
Query 281 --------LSYNNLN---VVGN--DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
LSY LN +VG L QL L N + ++ +
Sbjct 301 SELGNMSRLSYLQLNDNKLVGTIPPELGKLEQLFELNLANNRLVGPIPSNISSCAALNQF 360
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
N+ + SI LA F+ L L +LN+ N+ G +INL L LS
Sbjct 361 NVHGNLLSGSIPLA---------FRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLS 411
Query 388 -NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
N+F+ L T L H L ILNL++N +S F L ++++D+ N
Sbjct 412 GNNFSGSIPL---TLGDLEH--LLILNLSRNHLSGQLPAEFGNLRSIQMIDVSFN 461
>5xjo_A A LRR receptor-like serine/threonine-protein kinase ERL1
Length=539
Score = 40.8 bits (94), Expect = 0.067, Method: Compositional matrix adjust.
Identities = 120/470 (26%), Positives = 189/470 (40%), Gaps = 91/470 (19%)
Query 159 LSSTKLGTQV-----QLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFS 213
LSS LG ++ L NLQ + L NK+ +E+ A SL L+LS N +
Sbjct 51 LSSLNLGGEISPAIGDLRNLQSIDLQGNKLAGQIPDEIGNCA--SLVYLDLSENLLYGDI 108
Query 214 PGCFHAIGRLFGLFLNNVQLGPSLTEKLC-------LELA--------------NTSIRN 252
P + +L L L N QL + L L+LA N ++
Sbjct 109 PFSISKLKQLETLNLKNNQLTGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQY 168
Query 253 LSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQH 312
L L + L+ T ++ + T L D+ NNL +S + + YN I
Sbjct 169 LGLRGNMLTGTLSSDMC--QLTGLWYFDVRGNNLTGTIPESIGNCTSFQILDISYNQITG 226
Query 313 LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDND----IP 368
+++ G V L+L+ + I P++ ++ L L++ DN+ IP
Sbjct 227 EIPYNI-GFLQVATLSLQGNRLTGRI-----PEV----IGLMQALAVLDLSDNELVGPIP 276
Query 369 GIKSNM-FTGLINLKYLSLSNSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAF 427
I N+ FTG + L L+ S L N S L L L NK+
Sbjct 277 PILGNLSFTGKLYLHGNMLTGPIPS--ELGN-------MSRLSYLQLNDNKL-------- 319
Query 428 SWLGHLEVLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLML 487
+G + E+G+ LE +FE+ L+ N+ + ++ + +L + +
Sbjct 320 --VGTIPP------ELGK---------LEQLFELNLANNRLVGPIPSNISSCAALNQFNV 362
Query 488 RRVALKNVDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWK 547
L S P F+ L +LT L+LS+NN L + L+ LDL NN +
Sbjct 363 HGNLLSG--SIPLAFRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLSGNNFS---- 416
Query 548 HANPGGPIYFLKGLSHLHILNLESNGF-DEIPVEVFKDLFELKIIDLGLN 596
G L L HL ILNL N ++P E F +L +++ID+ N
Sbjct 417 ----GSIPLTLGDLEHLLILNLSRNHLSGQLPAE-FGNLRSIQMIDVSFN 461
Score = 38.9 bits (89), Expect = 0.30, Method: Compositional matrix adjust.
Identities = 106/415 (26%), Positives = 163/415 (39%), Gaps = 47/415 (11%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ ++L N+L + L LD+ N + P KL L+ LNL++N+L
Sbjct 69 NLQSIDLQGNKLAGQIPDEIGNCASLVYLDLSENLLYGDIPFSISKLKQLETLNLKNNQL 128
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ T NL L L N + + + L L L N L+ T QL
Sbjct 129 TGPVPATLTQIPNLKRLDLAGNHLTGEISRLLYWNEVLQYLGLRGNMLTGTLSSDMCQLT 188
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIG--RLFGLFLN 229
L + N + E I +S + L++S NQI P + IG ++ L L
Sbjct 189 GLWYFDVRGNNLTGTIPES--IGNCTSFQILDISYNQITGEIP---YNIGFLQVATLSLQ 243
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQL-----STTSNTTFLGLKWTNLTMLD---- 280
+L + E + L A + L LS+++L N +F G + + ML
Sbjct 244 GNRLTGRIPEVIGLMQA---LAVLDLSDNELVGPIPPILGNLSFTGKLYLHGNMLTGPIP 300
Query 281 --------LSYNNLN---VVGN--DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
LSY LN +VG L QL L N + ++ +
Sbjct 301 SELGNMSRLSYLQLNDNKLVGTIPPELGKLEQLFELNLANNRLVGPIPSNISSCAALNQF 360
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
N+ + SI LA F+ L L +LN+ N+ G +INL L LS
Sbjct 361 NVHGNLLSGSIPLA---------FRNLGSLTYLNLSSNNFKGKIPVELGHIINLDKLDLS 411
Query 388 -NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
N+F+ L T L H L ILNL++N +S F L ++++D+ N
Sbjct 412 GNNFSGSIPL---TLGDLEH--LLILNLSRNHLSGQLPAEFGNLRSIQMIDVSFN 461
>4puf_A A E3 ubiquitin-protein ligase SlrP
Length=637
Score = 40.8 bits (94), Expect = 0.069, Method: Compositional matrix adjust.
Identities = 38/125 (30%), Positives = 61/125 (49%), Gaps = 12/125 (10%)
Query 36 DCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
D H K++ +P++LP + L++ N +R LPA S++T L+V N+++ L PE
Sbjct 140 DLFHNKISCLPENLPEELRYLSVYDNSIRTLPAH---LPSEITHLNVQSNSLTAL-PETL 195
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
P LK L N L+ L + EL ++ S +I P + TLD+S
Sbjct 196 P--PGLKTLEAGENALTSLP------ASLPPELQVLDVSKNQITVLPETLPPTITTLDVS 247
Query 156 HNGLS 160
N L+
Sbjct 248 RNALT 252
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 45/165 (27%), Positives = 74/165 (45%), Gaps = 32/165 (19%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP- 99
+L +P++L NI L NQL +PA T + +++ N I+ EL ++LP
Sbjct 82 ELKSLPENLQGNIKTLYANSNQLTSIPA---TLPDTIQEMELSINRIT----ELPERLPS 134
Query 100 MLKVLNLQHNELSQLSD----------------KTFA--FCTNLTELHLMSNSIQKIKNN 141
L+ L+L HN++S L + +T + +T L++ SNS+ +
Sbjct 135 ALQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTLPAHLPSEITHLNVQSNSLTAL--- 191
Query 142 PFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQAL 186
P L TL+ N L+S + LQ L +S N+I L
Sbjct 192 PETLPPGLKTLEAGENALTSLPASLPPE---LQVLDVSKNQITVL 233
>4puf_B B E3 ubiquitin-protein ligase SlrP
Length=637
Score = 40.8 bits (94), Expect = 0.069, Method: Compositional matrix adjust.
Identities = 38/125 (30%), Positives = 61/125 (49%), Gaps = 12/125 (10%)
Query 36 DCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
D H K++ +P++LP + L++ N +R LPA S++T L+V N+++ L PE
Sbjct 140 DLFHNKISCLPENLPEELRYLSVYDNSIRTLPAH---LPSEITHLNVQSNSLTAL-PETL 195
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
P LK L N L+ L + EL ++ S +I P + TLD+S
Sbjct 196 P--PGLKTLEAGENALTSLP------ASLPPELQVLDVSKNQITVLPETLPPTITTLDVS 247
Query 156 HNGLS 160
N L+
Sbjct 248 RNALT 252
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 45/165 (27%), Positives = 74/165 (45%), Gaps = 32/165 (19%)
Query 41 KLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLP- 99
+L +P++L NI L NQL +PA T + +++ N I+ EL ++LP
Sbjct 82 ELKSLPENLQGNIKTLYANSNQLTSIPA---TLPDTIQEMELSINRIT----ELPERLPS 134
Query 100 MLKVLNLQHNELSQLSD----------------KTFA--FCTNLTELHLMSNSIQKIKNN 141
L+ L+L HN++S L + +T + +T L++ SNS+ +
Sbjct 135 ALQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTLPAHLPSEITHLNVQSNSLTAL--- 191
Query 142 PFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQAL 186
P L TL+ N L+S + LQ L +S N+I L
Sbjct 192 PETLPPGLKTLEAGENALTSLPASLPPE---LQVLDVSKNQITVL 233
>8fac_A A Leucine-rich repeat serine/threonine-protein kinase
1
Length=2048
Score = 40.4 bits (93), Expect = 0.11, Method: Compositional matrix adjust.
Identities = 45/155 (29%), Positives = 62/155 (40%), Gaps = 31/155 (20%)
Query 56 LNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL-EPELCQKLPMLKVLNLQHNELSQL 114
L+++ N+L LPA + L SL+V N + +P C LK N L L
Sbjct 418 LDISDNKLTELPALFLHSFKSLNSLNVSRNNLKVFPDPWACP----LKCCKASRNALECL 473
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
DK F N +L +D S N L LG QL+ L
Sbjct 474 PDKMAVFWKN-----------------------HLKDVDFSENALKEVPLGL-FQLDALM 509
Query 175 ELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
L L N++ AL +E + LK L+LS NQ+
Sbjct 510 FLRLQGNQLAALPPQEK--WTCRQLKTLDLSRNQL 542
>5hz0_A B Probable LRR receptor-like serine/threonine-protein
kinase At4g26540
Length=633
Score = 39.7 bits (91), Expect = 0.15, Method: Compositional matrix adjust.
Identities = 106/454 (23%), Positives = 174/454 (38%), Gaps = 82/454 (18%)
Query 119 FAFCTNLTELHLMSNSIQ----------KIKNNPFVKQKNLIT--------------LDL 154
+CT L L+L NSI K + + Q NL+ +D
Sbjct 202 IGYCTELQNLYLYQNSISGSIPTTIGGLKKLQSLLLWQNNLVGKIPTELGNCPELWLIDF 261
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
S N L+ T + +LENLQEL LS N+I EEL + L LE+ +N I P
Sbjct 262 SENLLTGTIPRSFGKLENLQELQLSVNQISGTIPEELT--NCTKLTHLEIDNNLITGEIP 319
Query 215 GCFHAIGRLFGLFLNNVQLGPSLTEKL--CLELANTSIRNLSLSNSQLSTTSNTTFLGLK 272
+ L F +L ++ + L C EL
Sbjct 320 SLMSNLRSLTMFFAWQNKLTGNIPQSLSQCRELQ-------------------------- 353
Query 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRY---LNL 329
+DLSYN+L+ +P+ E F L L S+ L G NL
Sbjct 354 -----AIDLSYNSLS-------GSIPK-EIFGLRNLTKLLLLSNDLSGFIPPDIGNCTNL 400
Query 330 KRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
R + S+P LK L +++ +N + G +G +L++L L +
Sbjct 401 YRLRLNGNRLAGSIPS----EIGNLKNLNFVDISENRLVGSIPPAISGCESLEFLDLHTN 456
Query 390 FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTG 449
+L+ + L ++ + N +S L L L+L N + E+
Sbjct 457 -----SLSGSLLGTTLPKSLKFIDFSDNALSSTLPPGIGLLTELTKLNLAKNRLSGEIP- 510
Query 450 QEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLT 509
+E ++ + L N + + +PSL + L + V PS F L+NL
Sbjct 511 REISTCRSLQLLNLGENDFSGEIPDELGQIPSLA-ISLNLSCNRFVGEIPSRFSDLKNLG 569
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
+LD+S+N + N ++L L+ L L++ +N+ +
Sbjct 570 VLDVSHNQLTG-NLNVLTDLQNLVSLNISYNDFS 602
Score = 36.6 bits (83), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 100/409 (24%), Positives = 168/409 (41%), Gaps = 32/409 (8%)
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
LDLS N LS +L+ L+ L L+ N ++ ++I S L +L L N++
Sbjct 66 LDLSDNSLSGDIPVEIFRLKKLKTLSLNTNNLEG--HIPMEIGNLSGLVELMLFDNKLSG 123
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANT-SIRNLSLSNSQLSTTSNTTFLG 270
P +IG L L + +L +L E+ N ++ L L+ + LS +
Sbjct 124 EIP---RSIGELKNLQVLRAGGNKNLRGELPWEIGNCENLVMLGLAETSLSGKLPASIGN 180
Query 271 LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
LK + S L+ D + +L+ +L N+I ++ GL ++ L L
Sbjct 181 LKRVQTIAIYTSL--LSGPIPDEIGYCTELQNLYLYQNSISGSIPTTIGGLKKLQSLLLW 238
Query 331 RS--FTKQSISLASLPKI--DDFS-----------FQWLKCLEHLNMEDNDIPGIKSNMF 375
++ K L + P++ DFS F L+ L+ L + N I G
Sbjct 239 QNNLVGKIPTELGNCPELWLIDFSENLLTGTIPRSFGKLENLQELQLSVNQISGTIPEEL 298
Query 376 TGLINLKYLSLSNSFTSLRTLTNETFVSLAH-SPLHILNLTKNKISKIESDAFSWLGHLE 434
T L +L + N+ +T E +++ L + +NK++ + S L+
Sbjct 299 TNCTKLTHLEIDNNL-----ITGEIPSLMSNLRSLTMFFAWQNKLTGNIPQSLSQCRELQ 353
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
+DL N + + +E GL N+ ++ L N +L RL L L
Sbjct 354 AIDLSYNSLSGSIP-KEIFGLRNLTKLLLLSNDLSGFIPPDIGNCTNLYRLRLNGNRL-- 410
Query 495 VDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
S PS L+NL +D+S N + + G E LE LDL N+L+
Sbjct 411 AGSIPSEIGNLKNLNFVDISENRLVGSIPPAISGCESLEFLDLHTNSLS 459
>5hz1_A B Probable LRR receptor-like serine/threonine-protein
kinase At4g26540
Length=633
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 106/454 (23%), Positives = 174/454 (38%), Gaps = 82/454 (18%)
Query 119 FAFCTNLTELHLMSNSIQ----------KIKNNPFVKQKNLIT--------------LDL 154
+CT L L+L NSI K + + Q NL+ +D
Sbjct 202 IGYCTELQNLYLYQNSISGSIPTTIGGLKKLQSLLLWQNNLVGKIPTELGNCPELWLIDF 261
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
S N L+ T + +LENLQEL LS N+I EEL + L LE+ +N I P
Sbjct 262 SENLLTGTIPRSFGKLENLQELQLSVNQISGTIPEELT--NCTKLTHLEIDNNLITGEIP 319
Query 215 GCFHAIGRLFGLFLNNVQLGPSLTEKL--CLELANTSIRNLSLSNSQLSTTSNTTFLGLK 272
+ L F +L ++ + L C EL
Sbjct 320 SLMSNLRSLTMFFAWQNKLTGNIPQSLSQCRELQ-------------------------- 353
Query 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRY---LNL 329
+DLSYN+L+ +P+ E F L L S+ L G NL
Sbjct 354 -----AIDLSYNSLS-------GSIPK-EIFGLRNLTKLLLLSNDLSGFIPPDIGNCTNL 400
Query 330 KRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
R + S+P LK L +++ +N + G +G +L++L L +
Sbjct 401 YRLRLNGNRLAGSIPS----EIGNLKNLNFVDISENRLVGSIPPAISGCESLEFLDLHTN 456
Query 390 FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTG 449
+L+ + L ++ + N +S L L L+L N + E+
Sbjct 457 -----SLSGSLLGTTLPKSLKFIDFSDNALSSTLPPGIGLLTELTKLNLAKNRLSGEIP- 510
Query 450 QEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLT 509
+E ++ + L N + + +PSL + L + V PS F L+NL
Sbjct 511 REISTCRSLQLLNLGENDFSGEIPDELGQIPSLA-ISLNLSCNRFVGEIPSRFSDLKNLG 569
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
+LD+S+N + N ++L L+ L L++ +N+ +
Sbjct 570 VLDVSHNQLTG-NLNVLTDLQNLVSLNISYNDFS 602
Score = 36.6 bits (83), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 100/409 (24%), Positives = 167/409 (41%), Gaps = 32/409 (8%)
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
LDLS N LS +L+ L+ L L+ N ++ E+ S L +L L N++
Sbjct 66 LDLSDNSLSGDIPVEIFRLKKLKTLSLNTNNLEGHIPMEIGNL--SGLVELMLFDNKLSG 123
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANT-SIRNLSLSNSQLSTTSNTTFLG 270
P +IG L L + +L +L E+ N ++ L L+ + LS +
Sbjct 124 EIP---RSIGELKNLQVLRAGGNKNLRGELPWEIGNCENLVMLGLAETSLSGKLPASIGN 180
Query 271 LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
LK + S L+ D + +L+ +L N+I ++ GL ++ L L
Sbjct 181 LKRVQTIAIYTSL--LSGPIPDEIGYCTELQNLYLYQNSISGSIPTTIGGLKKLQSLLLW 238
Query 331 RS--FTKQSISLASLPKI--DDFS-----------FQWLKCLEHLNMEDNDIPGIKSNMF 375
++ K L + P++ DFS F L+ L+ L + N I G
Sbjct 239 QNNLVGKIPTELGNCPELWLIDFSENLLTGTIPRSFGKLENLQELQLSVNQISGTIPEEL 298
Query 376 TGLINLKYLSLSNSFTSLRTLTNETFVSLAH-SPLHILNLTKNKISKIESDAFSWLGHLE 434
T L +L + N+ +T E +++ L + +NK++ + S L+
Sbjct 299 TNCTKLTHLEIDNNL-----ITGEIPSLMSNLRSLTMFFAWQNKLTGNIPQSLSQCRELQ 353
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
+DL N + + +E GL N+ ++ L N +L RL L L
Sbjct 354 AIDLSYNSLSGSIP-KEIFGLRNLTKLLLLSNDLSGFIPPDIGNCTNLYRLRLNGNRL-- 410
Query 495 VDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
S PS L+NL +D+S N + + G E LE LDL N+L+
Sbjct 411 AGSIPSEIGNLKNLNFVDISENRLVGSIPPAISGCESLEFLDLHTNSLS 459
>5hz3_A B Probable LRR receptor-like serine/threonine-protein
kinase At4g26540
Length=633
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 106/454 (23%), Positives = 174/454 (38%), Gaps = 82/454 (18%)
Query 119 FAFCTNLTELHLMSNSIQ----------KIKNNPFVKQKNLIT--------------LDL 154
+CT L L+L NSI K + + Q NL+ +D
Sbjct 202 IGYCTELQNLYLYQNSISGSIPTTIGGLKKLQSLLLWQNNLVGKIPTELGNCPELWLIDF 261
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
S N L+ T + +LENLQEL LS N+I EEL + L LE+ +N I P
Sbjct 262 SENLLTGTIPRSFGKLENLQELQLSVNQISGTIPEELT--NCTKLTHLEIDNNLITGEIP 319
Query 215 GCFHAIGRLFGLFLNNVQLGPSLTEKL--CLELANTSIRNLSLSNSQLSTTSNTTFLGLK 272
+ L F +L ++ + L C EL
Sbjct 320 SLMSNLRSLTMFFAWQNKLTGNIPQSLSQCRELQ-------------------------- 353
Query 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRY---LNL 329
+DLSYN+L+ +P+ E F L L S+ L G NL
Sbjct 354 -----AIDLSYNSLS-------GSIPK-EIFGLRNLTKLLLLSNDLSGFIPPDIGNCTNL 400
Query 330 KRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
R + S+P LK L +++ +N + G +G +L++L L +
Sbjct 401 YRLRLNGNRLAGSIPS----EIGNLKNLNFVDISENRLVGSIPPAISGCESLEFLDLHTN 456
Query 390 FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTG 449
+L+ + L ++ + N +S L L L+L N + E+
Sbjct 457 -----SLSGSLLGTTLPKSLKFIDFSDNALSSTLPPGIGLLTELTKLNLAKNRLSGEIP- 510
Query 450 QEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLT 509
+E ++ + L N + + +PSL + L + V PS F L+NL
Sbjct 511 REISTCRSLQLLNLGENDFSGEIPDELGQIPSLA-ISLNLSCNRFVGEIPSRFSDLKNLG 569
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
+LD+S+N + N ++L L+ L L++ +N+ +
Sbjct 570 VLDVSHNQLTG-NLNVLTDLQNLVSLNISYNDFS 602
Score = 36.6 bits (83), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 100/409 (24%), Positives = 168/409 (41%), Gaps = 32/409 (8%)
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
LDLS N LS +L+ L+ L L+ N ++ ++I S L +L L N++
Sbjct 66 LDLSDNSLSGDIPVEIFRLKKLKTLSLNTNNLEG--HIPMEIGNLSGLVELMLFDNKLSG 123
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANT-SIRNLSLSNSQLSTTSNTTFLG 270
P +IG L L + +L +L E+ N ++ L L+ + LS +
Sbjct 124 EIP---RSIGELKNLQVLRAGGNKNLRGELPWEIGNCENLVMLGLAETSLSGKLPASIGN 180
Query 271 LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
LK + S L+ D + +L+ +L N+I ++ GL ++ L L
Sbjct 181 LKRVQTIAIYTSL--LSGPIPDEIGYCTELQNLYLYQNSISGSIPTTIGGLKKLQSLLLW 238
Query 331 RS--FTKQSISLASLPKI--DDFS-----------FQWLKCLEHLNMEDNDIPGIKSNMF 375
++ K L + P++ DFS F L+ L+ L + N I G
Sbjct 239 QNNLVGKIPTELGNCPELWLIDFSENLLTGTIPRSFGKLENLQELQLSVNQISGTIPEEL 298
Query 376 TGLINLKYLSLSNSFTSLRTLTNETFVSLAH-SPLHILNLTKNKISKIESDAFSWLGHLE 434
T L +L + N+ +T E +++ L + +NK++ + S L+
Sbjct 299 TNCTKLTHLEIDNNL-----ITGEIPSLMSNLRSLTMFFAWQNKLTGNIPQSLSQCRELQ 353
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
+DL N + + +E GL N+ ++ L N +L RL L L
Sbjct 354 AIDLSYNSLSGSIP-KEIFGLRNLTKLLLLSNDLSGFIPPDIGNCTNLYRLRLNGNRL-- 410
Query 495 VDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
S PS L+NL +D+S N + + G E LE LDL N+L+
Sbjct 411 AGSIPSEIGNLKNLNFVDISENRLVGSIPPAISGCESLEFLDLHTNSLS 459
>5hyx_A B Probable LRR receptor-like serine/threonine-protein
kinase At4g26540
Length=633
Score = 39.7 bits (91), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 106/454 (23%), Positives = 174/454 (38%), Gaps = 82/454 (18%)
Query 119 FAFCTNLTELHLMSNSIQ----------KIKNNPFVKQKNLIT--------------LDL 154
+CT L L+L NSI K + + Q NL+ +D
Sbjct 202 IGYCTELQNLYLYQNSISGSIPTTIGGLKKLQSLLLWQNNLVGKIPTELGNCPELWLIDF 261
Query 155 SHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSP 214
S N L+ T + +LENLQEL LS N+I EEL + L LE+ +N I P
Sbjct 262 SENLLTGTIPRSFGKLENLQELQLSVNQISGTIPEELT--NCTKLTHLEIDNNLITGEIP 319
Query 215 GCFHAIGRLFGLFLNNVQLGPSLTEKL--CLELANTSIRNLSLSNSQLSTTSNTTFLGLK 272
+ L F +L ++ + L C EL
Sbjct 320 SLMSNLRSLTMFFAWQNKLTGNIPQSLSQCRELQ-------------------------- 353
Query 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRY---LNL 329
+DLSYN+L+ +P+ E F L L S+ L G NL
Sbjct 354 -----AIDLSYNSLS-------GSIPK-EIFGLRNLTKLLLLSNDLSGFIPPDIGNCTNL 400
Query 330 KRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNS 389
R + S+P LK L +++ +N + G +G +L++L L +
Sbjct 401 YRLRLNGNRLAGSIPS----EIGNLKNLNFVDISENRLVGSIPPAISGCESLEFLDLHTN 456
Query 390 FTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTG 449
+L+ + L ++ + N +S L L L+L N + E+
Sbjct 457 -----SLSGSLLGTTLPKSLKFIDFSDNALSSTLPPGIGLLTELTKLNLAKNRLSGEIP- 510
Query 450 QEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLT 509
+E ++ + L N + + +PSL + L + V PS F L+NL
Sbjct 511 REISTCRSLQLLNLGENDFSGEIPDELGQIPSLA-ISLNLSCNRFVGEIPSRFSDLKNLG 569
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
+LD+S+N + N ++L L+ L L++ +N+ +
Sbjct 570 VLDVSHNQLTG-NLNVLTDLQNLVSLNISYNDFS 602
Score = 36.6 bits (83), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 100/409 (24%), Positives = 168/409 (41%), Gaps = 32/409 (8%)
Query 152 LDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKE 211
LDLS N LS +L+ L+ L L+ N ++ ++I S L +L L N++
Sbjct 66 LDLSDNSLSGDIPVEIFRLKKLKTLSLNTNNLEG--HIPMEIGNLSGLVELMLFDNKLSG 123
Query 212 FSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELANT-SIRNLSLSNSQLSTTSNTTFLG 270
P +IG L L + +L +L E+ N ++ L L+ + LS +
Sbjct 124 EIP---RSIGELKNLQVLRAGGNKNLRGELPWEIGNCENLVMLGLAETSLSGKLPASIGN 180
Query 271 LKWTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLK 330
LK + S L+ D + +L+ +L N+I ++ GL ++ L L
Sbjct 181 LKRVQTIAIYTSL--LSGPIPDEIGYCTELQNLYLYQNSISGSIPTTIGGLKKLQSLLLW 238
Query 331 RS--FTKQSISLASLPKI--DDFS-----------FQWLKCLEHLNMEDNDIPGIKSNMF 375
++ K L + P++ DFS F L+ L+ L + N I G
Sbjct 239 QNNLVGKIPTELGNCPELWLIDFSENLLTGTIPRSFGKLENLQELQLSVNQISGTIPEEL 298
Query 376 TGLINLKYLSLSNSFTSLRTLTNETFVSLAH-SPLHILNLTKNKISKIESDAFSWLGHLE 434
T L +L + N+ +T E +++ L + +NK++ + S L+
Sbjct 299 TNCTKLTHLEIDNNL-----ITGEIPSLMSNLRSLTMFFAWQNKLTGNIPQSLSQCRELQ 353
Query 435 VLDLGLNEIGQELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKN 494
+DL N + + +E GL N+ ++ L N +L RL L L
Sbjct 354 AIDLSYNSLSGSIP-KEIFGLRNLTKLLLLSNDLSGFIPPDIGNCTNLYRLRLNGNRL-- 410
Query 495 VDSSPSPFQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
S PS L+NL +D+S N + + G E LE LDL N+L+
Sbjct 411 AGSIPSEIGNLKNLNFVDISENRLVGSIPPAISGCESLEFLDLHTNSLS 459
>7ax1_A A CCR4-NOT transcription complex subunit 6
Length=563
Score = 39.7 bits (91), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 31/87 (36%), Positives = 48/87 (55%), Gaps = 4/87 (5%)
Query 561 LSHLHILNLESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
L+HL L+L N IP ++ K L L +DL N + +LPA + N VSL+ L+L N
Sbjct 56 LTHLTALHLSDNSLSRIPSDIAK-LHNLVYLDLSSNKIRSLPAEL-GNMVSLRELHLNNN 113
Query 621 LITSVEKKVFGPAFRNLTELDMRFNPF 647
L+ + ++ G F+ L L ++ NP
Sbjct 114 LLRVLPFEL-GKLFQ-LQTLGLKGNPL 138
Score = 38.5 bits (88), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 34/91 (37%), Positives = 51/91 (56%), Gaps = 9/91 (10%)
Query 123 TNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS--TKLGTQVQLENLQELLLSN 180
T+LT LHL NS+ +I ++ K NL+ LDLS N + S +LG V +L+EL L+N
Sbjct 57 THLTALHLSDNSLSRIPSD-IAKLHNLVYLDLSSNKIRSLPAELGNMV---SLRELHLNN 112
Query 181 NKIQALKSEELDIFANSSLKKLELSSNQIKE 211
N ++ L E +F L+ L L N + +
Sbjct 113 NLLRVLPFELGKLF---QLQTLGLKGNPLTQ 140
>7brc_A A Receptor-like kinase TMK3
Length=458
Score = 39.3 bits (90), Expect = 0.18, Method: Compositional matrix adjust.
Identities = 103/404 (25%), Positives = 161/404 (40%), Gaps = 61/404 (15%)
Query 53 ITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELS 112
+T + L +R N S+L L++ N IS P+L L L+ LNL N +
Sbjct 43 VTKIQLKQKGIRGTLPTNLQSLSELVILELFLNRISGPIPDL-SGLSRLQTLNLHDNLFT 101
Query 113 QLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLEN 172
+ F+ ++L E++L +NNPF + D T + +
Sbjct 102 SVPKNLFSGMSSLQEMYL--------ENNPF---DPWVIPD------------TVKEATS 138
Query 173 LQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQ 232
LQ L LSN I + + SL L+LS N ++ P F + LFLN +
Sbjct 139 LQNLTLSNCSIIGKIPDFFGSQSLPSLTNLKLSQNGLEGELPMSFAGT-SIQSLFLNGQK 197
Query 233 LGPSLTEKLCLELAN-TSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGN 291
L S++ L N TS+ +SL +Q S GL +L + ++ N L V
Sbjct 198 LNGSISV-----LGNMTSLVEVSLQGNQFSGPI-PDLSGL--VSLRVFNVRENQLTGVVP 249
Query 292 DSFAWLPQLEYFFLEYNNIQH---LFSHSLHGLFNVRYLNLKRSFTKQSISLASLPKIDD 348
S L L L N +Q LF S+ V +N SF A P++D
Sbjct 250 QSLVSLSSLTTVNLTNNYLQGPTPLFGKSVG----VDIVNNMNSFCTNVAGEACDPRVDT 305
Query 349 F-----SFQW-LKCLEHLNMEDNDIPGIKSNMFTG---LINLKYLSLSNSFT-SLRTLTN 398
SF + +K E + + + G ++N++ LS + + SL LT+
Sbjct 306 LVSVAESFGYPVKLAESWKGNNPCVNWVGITCSGGNITVVNMRKQDLSGTISPSLAKLTS 365
Query 399 ETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNE 442
L +NL NK+S D + L L +LD+ N+
Sbjct 366 ----------LETINLADNKLSGHIPDELTTLSKLRLLDVSNND 399
Score = 34.3 bits (77), Expect = 7.3, Method: Compositional matrix adjust.
Identities = 23/64 (36%), Positives = 32/64 (50%), Gaps = 9/64 (14%)
Query 526 LEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPVEVFKDL 585
L+ L +L IL+L N ++ GPI L GLS L LNL N F +P +F +
Sbjct 61 LQSLSELVILELFLNRIS---------GPIPDLSGLSRLQTLNLHDNLFTSVPKNLFSGM 111
Query 586 FELK 589
L+
Sbjct 112 SSLQ 115
>5xkn_C B LRR receptor-like serine/threonine-protein kinase ERL2
Length=552
Score = 39.3 bits (90), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 106/415 (26%), Positives = 162/415 (39%), Gaps = 47/415 (11%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ ++L N+L L +D N + P KL L+ LNL++N+L
Sbjct 69 NLQSIDLQGNKLGGQIPDEIGNCVSLAYVDFSTNLLFGDIPFSISKLKQLEFLNLKNNQL 128
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ T NL L L N + + L L L N L+ T QL
Sbjct 129 TGPIPATLTQIPNLKTLDLARNQLTGEIPRLLYWNEVLQYLGLRGNMLTGTLSPDMCQLT 188
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIG--RLFGLFLN 229
L + N + E I +S + L++S NQI P + IG ++ L L
Sbjct 189 GLWYFDVRGNNLTGTIPES--IGNCTSFEILDVSYNQITGVIP---YNIGFLQVATLSLQ 243
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT-----SNTTFLG---LKWTNLT---- 277
+L + E + L A + L LS+++L+ N +F G L LT
Sbjct 244 GNKLTGRIPEVIGLMQA---LAVLDLSDNELTGPIPPILGNLSFTGKLYLHGNKLTGQIP 300
Query 278 -----MLDLSYNNLN---VVGN--DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
M LSY LN +VG L QL L NN+ L ++ +
Sbjct 301 PELGNMSRLSYLQLNDNELVGKIPPELGKLEQLFELNLANNNLVGLIPSNISSCAALNQF 360
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
N+ +F ++ L F+ L L +LN+ N G +INL L LS
Sbjct 361 NVHGNFLSGAVPL---------EFRNLGSLTYLNLSSNSFKGKIPAELGHIINLDTLDLS 411
Query 388 -NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
N+F+ L T L H L ILNL++N ++ F L ++++D+ N
Sbjct 412 GNNFSGSIPL---TLGDLEH--LLILNLSRNHLNGTLPAEFGNLRSIQIIDVSFN 461
>5xkn_B A LRR receptor-like serine/threonine-protein kinase ERL2
Length=552
Score = 39.3 bits (90), Expect = 0.19, Method: Compositional matrix adjust.
Identities = 106/415 (26%), Positives = 162/415 (39%), Gaps = 47/415 (11%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNEL 111
N+ ++L N+L L +D N + P KL L+ LNL++N+L
Sbjct 69 NLQSIDLQGNKLGGQIPDEIGNCVSLAYVDFSTNLLFGDIPFSISKLKQLEFLNLKNNQL 128
Query 112 SQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLE 171
+ T NL L L N + + L L L N L+ T QL
Sbjct 129 TGPIPATLTQIPNLKTLDLARNQLTGEIPRLLYWNEVLQYLGLRGNMLTGTLSPDMCQLT 188
Query 172 NLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIG--RLFGLFLN 229
L + N + E I +S + L++S NQI P + IG ++ L L
Sbjct 189 GLWYFDVRGNNLTGTIPES--IGNCTSFEILDVSYNQITGVIP---YNIGFLQVATLSLQ 243
Query 230 NVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTT-----SNTTFLG---LKWTNLT---- 277
+L + E + L A + L LS+++L+ N +F G L LT
Sbjct 244 GNKLTGRIPEVIGLMQA---LAVLDLSDNELTGPIPPILGNLSFTGKLYLHGNKLTGQIP 300
Query 278 -----MLDLSYNNLN---VVGN--DSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYL 327
M LSY LN +VG L QL L NN+ L ++ +
Sbjct 301 PELGNMSRLSYLQLNDNELVGKIPPELGKLEQLFELNLANNNLVGLIPSNISSCAALNQF 360
Query 328 NLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS 387
N+ +F ++ L F+ L L +LN+ N G +INL L LS
Sbjct 361 NVHGNFLSGAVPL---------EFRNLGSLTYLNLSSNSFKGKIPAELGHIINLDTLDLS 411
Query 388 -NSFTSLRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLN 441
N+F+ L T L H L ILNL++N ++ F L ++++D+ N
Sbjct 412 GNNFSGSIPL---TLGDLEH--LLILNLSRNHLNGTLPAEFGNLRSIQIIDVSFN 461
>8esf_B B Nischarin
Length=502
Score = 38.9 bits (89), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 41/145 (28%), Positives = 73/145 (50%), Gaps = 32/145 (22%)
Query 68 AANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTE 127
A + LT+LD+ N IS ++ E + +P ++ L+L HNEL
Sbjct 314 TAVIPTWQALTTLDLSHNCISCID-ESVKLIPKIEFLDLSHNEL---------------- 356
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALK 187
L+ +++Q + N L+ LDLS+N L+S + G +L N++ L L+ N +++L
Sbjct 357 --LVVDNLQHLYN--------LVHLDLSYNKLTSLE-GLHTKLGNIKTLNLAGNLLESLS 405
Query 188 SEELDIFANSSLKKLELSSNQIKEF 212
+ SL L+LS+N+I++
Sbjct 406 G----LHKLYSLVNLDLSNNRIEQM 426
Score = 37.7 bits (86), Expect = 0.56, Method: Compositional matrix adjust.
Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 34/138 (25%)
Query 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN------NIQHLFS----------- 315
W LT LDLS+N ++ + ++S +P++E+ L +N N+QHL++
Sbjct 320 WQALTTLDLSHNCISCI-DESVKLIPKIEFLDLSHNELLVVDNLQHLYNLVHLDLSYNKL 378
Query 316 HSLHGLF----NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIK 371
SL GL N++ LNL + + SL+ L K L L +L++ +N I ++
Sbjct 379 TSLEGLHTKLGNIKTLNLAGNLLE---SLSGLHK--------LYSLVNLDLSNNRIEQME 427
Query 372 SNMFTG-LINLKYLSLSN 388
G L L+YLSL+N
Sbjct 428 EVRHIGSLPCLEYLSLTN 445
>3cvr_A A Invasion plasmid antigen
Length=615
Score = 39.3 bits (90), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 47/132 (36%), Positives = 64/132 (48%), Gaps = 14/132 (11%)
Query 39 HLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKL 98
L L+ +PD+LP ITVL +T N L LP + L LD N +S L PEL L
Sbjct 68 RLNLSSLPDNLPPQITVLEITQNALISLPELP----ASLEYLDACDNRLSTL-PELPASL 122
Query 99 PMLKVLNLQHN---ELSQLSDKTFAFCTNLTELHLMSNSIQ--KIKNN--PFVKQ--KNL 149
L V N Q EL L + A LT L + S++ ++NN F+ + ++L
Sbjct 123 KHLDVDNNQLTMLPELPALLEYINADNNQLTMLPELPTSLEVLSVRNNQLTFLPELPESL 182
Query 150 ITLDLSHNGLSS 161
LD+S N L S
Sbjct 183 EALDVSTNLLES 194
>8e06_A A Leucine-rich repeat serine/threonine-protein kinase
1
Length=2016
Score = 39.3 bits (90), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 61/227 (27%), Positives = 93/227 (41%), Gaps = 30/227 (13%)
Query 4 TLPCIYFWG--------------GLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDL 49
TLP + WG G LP + +S C+ E+ D S KL+ +P
Sbjct 293 TLPSVIPWGLINLRKLNLSDNHLGELP--GVQSSDEIICSRLLEI-DISSNKLSHLPPGF 349
Query 50 P--TNITVLNLTHNQLRRL----PAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKV 103
+ + L + N L +L A N+ +L LD+ N +++L L
Sbjct 350 LHLSKLQKLTASKNCLEKLFEEENATNWIGLRKLQELDISDNKLTELPALFLHSFKSLNS 409
Query 104 LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN-LITLDLSHNGLSST 162
LN+ N L D + L N+++ + + V KN L +D S N L
Sbjct 410 LNVSRNNLKVFPD---PWACPLKCCKASRNALECLPDKMAVFWKNHLKDVDFSENALKEV 466
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
LG QL+ L L L N++ AL +E + LK L+LS NQ+
Sbjct 467 PLGL-FQLDALMFLRLQGNQLAALPPQE--KWTCRQLKTLDLSRNQL 510
Score = 38.9 bits (89), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 45/146 (31%), Positives = 66/146 (45%), Gaps = 14/146 (10%)
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL-----SDKTFAFCTNLTELHL 130
Q+T LD+ N ++ L + L L+ LNL N L +L SD+ C+ L E+ +
Sbjct 280 QITELDLSANCLATLPSVIPWGLINLRKLNLSDNHLGELPGVQSSDEI--ICSRLLEIDI 337
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGL----SSTKLGTQVQLENLQELLLSNNKIQAL 186
SN + + F+ L L S N L + L LQEL +S+NK+ L
Sbjct 338 SSNKLSHLPPG-FLHLSKLQKLTASKNCLEKLFEEENATNWIGLRKLQELDISDNKLTEL 396
Query 187 KSEELDIFANSSLKKLELSSNQIKEF 212
+ L F SL L +S N +K F
Sbjct 397 PALFLHSF--KSLNSLNVSRNNLKVF 420
Score = 38.1 bits (87), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 64/234 (27%), Positives = 102/234 (44%), Gaps = 27/234 (12%)
Query 42 LTQVPDDLP---TNITVLNLTHNQLRRLPAANFTR---YSQLTSLDVGFNTISKLEPELC 95
L +P +P N+ LNL+ N L LP + S+L +D+ N +S L P
Sbjct 291 LATLPSVIPWGLINLRKLNLSDNHLGELPGVQSSDEIICSRLLEIDISSNKLSHLPPGFL 350
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTN------LTELHLMSNSIQKIKNNPFVKQKNL 149
L L+ L N L +L ++ A TN L EL + N + ++ K+L
Sbjct 351 H-LSKLQKLTASKNCLEKLFEEENA--TNWIGLRKLQELDISDNKLTELPALFLHSFKSL 407
Query 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
+L++S N L K+ L+ S N ++ L +++ +F + LK ++ S N +
Sbjct 408 NSLNVSRNNL---KVFPDPWACPLKCCKASRNALECL-PDKMAVFWKNHLKDVDFSENAL 463
Query 210 KEFSPGCFHAIGRLFGLFLNNVQLG--PSLTEKLCLELANTSIRNLSLSNSQLS 261
KE G F +F L L QL P + C +L + L LS +QL
Sbjct 464 KEVPLGLFQLDALMF-LRLQGNQLAALPPQEKWTCRQL-----KTLDLSRNQLG 511
Score = 35.8 bits (81), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 53/287 (18%)
Query 343 LPKIDDFSFQWL---KC-LEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLT 397
LP +D WL C + L++ N + + S + GLINL+ L+LS N L +
Sbjct 266 LPWVD---LDWLIDISCQITELDLSANCLATLPSVIPWGLINLRKLNLSDNHLGELPGVQ 322
Query 398 NETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLG---LNEIGQELTGQEWRG 454
+ + S L ++++ NK+S + F L L+ L L ++ +E W G
Sbjct 323 SSD--EIICSRLLEIDISSNKLSHLPP-GFLHLSKLQKLTASKNCLEKLFEEENATNWIG 379
Query 455 LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ-PLRNLTILDL 513
L + E+ +S NK +L SL L + R N+ P P+ PL+
Sbjct 380 LRKLQELDISDNKLTELPALFLHSFKSLNSLNVSR---NNLKVFPDPWACPLK---CCKA 433
Query 514 SNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNG 573
S N + + D M A WK+ HL ++ N
Sbjct 434 SRNALECLPDKM-----------------AVFWKN--------------HLKDVDFSENA 462
Query 574 FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
E+P+ +F+ L L + L N L LP LK+L+L +N
Sbjct 463 LKEVPLGLFQ-LDALMFLRLQGNQLAALPPQEKWTCRQLKTLDLSRN 508
>8e05_A A Leucine-rich repeat serine/threonine-protein kinase
1
Length=2016
Score = 39.3 bits (90), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 61/227 (27%), Positives = 93/227 (41%), Gaps = 30/227 (13%)
Query 4 TLPCIYFWG--------------GLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDL 49
TLP + WG G LP + +S C+ E+ D S KL+ +P
Sbjct 293 TLPSVIPWGLINLRKLNLSDNHLGELP--GVQSSDEIICSRLLEI-DISSNKLSHLPPGF 349
Query 50 P--TNITVLNLTHNQLRRL----PAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKV 103
+ + L + N L +L A N+ +L LD+ N +++L L
Sbjct 350 LHLSKLQKLTASKNCLEKLFEEENATNWIGLRKLQELDISDNKLTELPALFLHSFKSLNS 409
Query 104 LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN-LITLDLSHNGLSST 162
LN+ N L D + L N+++ + + V KN L +D S N L
Sbjct 410 LNVSRNNLKVFPD---PWACPLKCCKASRNALECLPDKMAVFWKNHLKDVDFSENALKEV 466
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
LG QL+ L L L N++ AL +E + LK L+LS NQ+
Sbjct 467 PLGL-FQLDALMFLRLQGNQLAALPPQE--KWTCRQLKTLDLSRNQL 510
Score = 38.9 bits (89), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 45/146 (31%), Positives = 66/146 (45%), Gaps = 14/146 (10%)
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL-----SDKTFAFCTNLTELHL 130
Q+T LD+ N ++ L + L L+ LNL N L +L SD+ C+ L E+ +
Sbjct 280 QITELDLSANCLATLPSVIPWGLINLRKLNLSDNHLGELPGVQSSDEI--ICSRLLEIDI 337
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGL----SSTKLGTQVQLENLQELLLSNNKIQAL 186
SN + + F+ L L S N L + L LQEL +S+NK+ L
Sbjct 338 SSNKLSHLPPG-FLHLSKLQKLTASKNCLEKLFEEENATNWIGLRKLQELDISDNKLTEL 396
Query 187 KSEELDIFANSSLKKLELSSNQIKEF 212
+ L F SL L +S N +K F
Sbjct 397 PALFLHSF--KSLNSLNVSRNNLKVF 420
Score = 38.1 bits (87), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 64/234 (27%), Positives = 102/234 (44%), Gaps = 27/234 (12%)
Query 42 LTQVPDDLP---TNITVLNLTHNQLRRLPAANFTR---YSQLTSLDVGFNTISKLEPELC 95
L +P +P N+ LNL+ N L LP + S+L +D+ N +S L P
Sbjct 291 LATLPSVIPWGLINLRKLNLSDNHLGELPGVQSSDEIICSRLLEIDISSNKLSHLPPGFL 350
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTN------LTELHLMSNSIQKIKNNPFVKQKNL 149
L L+ L N L +L ++ A TN L EL + N + ++ K+L
Sbjct 351 H-LSKLQKLTASKNCLEKLFEEENA--TNWIGLRKLQELDISDNKLTELPALFLHSFKSL 407
Query 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
+L++S N L K+ L+ S N ++ L +++ +F + LK ++ S N +
Sbjct 408 NSLNVSRNNL---KVFPDPWACPLKCCKASRNALECL-PDKMAVFWKNHLKDVDFSENAL 463
Query 210 KEFSPGCFHAIGRLFGLFLNNVQLG--PSLTEKLCLELANTSIRNLSLSNSQLS 261
KE G F +F L L QL P + C +L + L LS +QL
Sbjct 464 KEVPLGLFQLDALMF-LRLQGNQLAALPPQEKWTCRQL-----KTLDLSRNQLG 511
Score = 35.8 bits (81), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 53/287 (18%)
Query 343 LPKIDDFSFQWL---KC-LEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLT 397
LP +D WL C + L++ N + + S + GLINL+ L+LS N L +
Sbjct 266 LPWVD---LDWLIDISCQITELDLSANCLATLPSVIPWGLINLRKLNLSDNHLGELPGVQ 322
Query 398 NETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLG---LNEIGQELTGQEWRG 454
+ + S L ++++ NK+S + F L L+ L L ++ +E W G
Sbjct 323 SSD--EIICSRLLEIDISSNKLSHLPP-GFLHLSKLQKLTASKNCLEKLFEEENATNWIG 379
Query 455 LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ-PLRNLTILDL 513
L + E+ +S NK +L SL L + R N+ P P+ PL+
Sbjct 380 LRKLQELDISDNKLTELPALFLHSFKSLNSLNVSR---NNLKVFPDPWACPLK---CCKA 433
Query 514 SNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNG 573
S N + + D M A WK+ HL ++ N
Sbjct 434 SRNALECLPDKM-----------------AVFWKN--------------HLKDVDFSENA 462
Query 574 FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
E+P+ +F+ L L + L N L LP LK+L+L +N
Sbjct 463 LKEVPLGLFQ-LDALMFLRLQGNQLAALPPQEKWTCRQLKTLDLSRN 508
>8e05_B B Leucine-rich repeat serine/threonine-protein kinase
1
Length=2016
Score = 39.3 bits (90), Expect = 0.23, Method: Compositional matrix adjust.
Identities = 61/227 (27%), Positives = 93/227 (41%), Gaps = 30/227 (13%)
Query 4 TLPCIYFWG--------------GLLPFGMLCASSTTKCTVSHEVADCSHLKLTQVPDDL 49
TLP + WG G LP + +S C+ E+ D S KL+ +P
Sbjct 293 TLPSVIPWGLINLRKLNLSDNHLGELP--GVQSSDEIICSRLLEI-DISSNKLSHLPPGF 349
Query 50 P--TNITVLNLTHNQLRRL----PAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKV 103
+ + L + N L +L A N+ +L LD+ N +++L L
Sbjct 350 LHLSKLQKLTASKNCLEKLFEEENATNWIGLRKLQELDISDNKLTELPALFLHSFKSLNS 409
Query 104 LNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKN-LITLDLSHNGLSST 162
LN+ N L D + L N+++ + + V KN L +D S N L
Sbjct 410 LNVSRNNLKVFPD---PWACPLKCCKASRNALECLPDKMAVFWKNHLKDVDFSENALKEV 466
Query 163 KLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
LG QL+ L L L N++ AL +E + LK L+LS NQ+
Sbjct 467 PLGL-FQLDALMFLRLQGNQLAALPPQE--KWTCRQLKTLDLSRNQL 510
Score = 38.9 bits (89), Expect = 0.34, Method: Compositional matrix adjust.
Identities = 45/146 (31%), Positives = 66/146 (45%), Gaps = 14/146 (10%)
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL-----SDKTFAFCTNLTELHL 130
Q+T LD+ N ++ L + L L+ LNL N L +L SD+ C+ L E+ +
Sbjct 280 QITELDLSANCLATLPSVIPWGLINLRKLNLSDNHLGELPGVQSSDEI--ICSRLLEIDI 337
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGL----SSTKLGTQVQLENLQELLLSNNKIQAL 186
SN + + F+ L L S N L + L LQEL +S+NK+ L
Sbjct 338 SSNKLSHLPPG-FLHLSKLQKLTASKNCLEKLFEEENATNWIGLRKLQELDISDNKLTEL 396
Query 187 KSEELDIFANSSLKKLELSSNQIKEF 212
+ L F SL L +S N +K F
Sbjct 397 PALFLHSF--KSLNSLNVSRNNLKVF 420
Score = 38.1 bits (87), Expect = 0.62, Method: Compositional matrix adjust.
Identities = 64/234 (27%), Positives = 102/234 (44%), Gaps = 27/234 (12%)
Query 42 LTQVPDDLP---TNITVLNLTHNQLRRLPAANFTR---YSQLTSLDVGFNTISKLEPELC 95
L +P +P N+ LNL+ N L LP + S+L +D+ N +S L P
Sbjct 291 LATLPSVIPWGLINLRKLNLSDNHLGELPGVQSSDEIICSRLLEIDISSNKLSHLPPGFL 350
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTN------LTELHLMSNSIQKIKNNPFVKQKNL 149
L L+ L N L +L ++ A TN L EL + N + ++ K+L
Sbjct 351 H-LSKLQKLTASKNCLEKLFEEENA--TNWIGLRKLQELDISDNKLTELPALFLHSFKSL 407
Query 150 ITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQI 209
+L++S N L K+ L+ S N ++ L +++ +F + LK ++ S N +
Sbjct 408 NSLNVSRNNL---KVFPDPWACPLKCCKASRNALECL-PDKMAVFWKNHLKDVDFSENAL 463
Query 210 KEFSPGCFHAIGRLFGLFLNNVQLG--PSLTEKLCLELANTSIRNLSLSNSQLS 261
KE G F +F L L QL P + C +L + L LS +QL
Sbjct 464 KEVPLGLFQLDALMF-LRLQGNQLAALPPQEKWTCRQL-----KTLDLSRNQLG 511
Score = 35.8 bits (81), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 53/287 (18%)
Query 343 LPKIDDFSFQWL---KC-LEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTSLRTLT 397
LP +D WL C + L++ N + + S + GLINL+ L+LS N L +
Sbjct 266 LPWVD---LDWLIDISCQITELDLSANCLATLPSVIPWGLINLRKLNLSDNHLGELPGVQ 322
Query 398 NETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLG---LNEIGQELTGQEWRG 454
+ + S L ++++ NK+S + F L L+ L L ++ +E W G
Sbjct 323 SSD--EIICSRLLEIDISSNKLSHLPP-GFLHLSKLQKLTASKNCLEKLFEEENATNWIG 379
Query 455 LENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQ-PLRNLTILDL 513
L + E+ +S NK +L SL L + R N+ P P+ PL+
Sbjct 380 LRKLQELDISDNKLTELPALFLHSFKSLNSLNVSR---NNLKVFPDPWACPLK---CCKA 433
Query 514 SNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNG 573
S N + + D M A WK+ HL ++ N
Sbjct 434 SRNALECLPDKM-----------------AVFWKN--------------HLKDVDFSENA 462
Query 574 FDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKN 620
E+P+ +F+ L L + L N L LP LK+L+L +N
Sbjct 463 LKEVPLGLFQ-LDALMFLRLQGNQLAALPPQEKWTCRQLKTLDLSRN 508
>8esf_A A Nischarin
Length=502
Score = 38.5 bits (88), Expect = 0.33, Method: Compositional matrix adjust.
Identities = 40/139 (29%), Positives = 72/139 (52%), Gaps = 32/139 (23%)
Query 74 YSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
+ LT+LD+ N IS ++ E + +P ++ L+L HNEL L+ +
Sbjct 320 WQALTTLDLSHNCISCID-ESVKLIPKIEFLDLSHNEL------------------LVVD 360
Query 134 SIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDI 193
++Q + N L+ LDLS+N L+S + G +L N++ L L+ N +++L +
Sbjct 361 NLQHLYN--------LVHLDLSYNKLTSLE-GLHTKLGNIKTLNLAGNLLESLSG----L 407
Query 194 FANSSLKKLELSSNQIKEF 212
SL L+LS+N+I++
Sbjct 408 HKLYSLVNLDLSNNRIEQM 426
Score = 38.1 bits (87), Expect = 0.47, Method: Compositional matrix adjust.
Identities = 42/138 (30%), Positives = 69/138 (50%), Gaps = 34/138 (25%)
Query 273 WTNLTMLDLSYNNLNVVGNDSFAWLPQLEYFFLEYN------NIQHLFS----------- 315
W LT LDLS+N ++ + ++S +P++E+ L +N N+QHL++
Sbjct 320 WQALTTLDLSHNCISCI-DESVKLIPKIEFLDLSHNELLVVDNLQHLYNLVHLDLSYNKL 378
Query 316 HSLHGLF----NVRYLNLKRSFTKQSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIK 371
SL GL N++ LNL + + SL+ L K L L +L++ +N I ++
Sbjct 379 TSLEGLHTKLGNIKTLNLAGNLLE---SLSGLHK--------LYSLVNLDLSNNRIEQME 427
Query 372 SNMFTG-LINLKYLSLSN 388
G L L+YLSL+N
Sbjct 428 EVRHIGSLPCLEYLSLTN 445
>6w78_A A Antifreeze polypeptide
Length=336
Score = 38.1 bits (87), Expect = 0.35, Method: Compositional matrix adjust.
Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 4/106 (4%)
Query 71 FTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHL 130
F + ++LT LD+ FN + + P LP LK L+L+ NEL+ F +++L
Sbjct 142 FPQLTKLTCLDLSFNKLLGVIPPQLSTLPNLKALHLERNELTGEIPDIFGNFAGSPDIYL 201
Query 131 MSNSIQKIKNNPFVKQKNLITLDLSHNGLS---STKLGTQVQLENL 173
N + F + + I LD S N L S G + +LE L
Sbjct 202 SHNQLTGFVPKTFAR-ADPIRLDFSGNRLEGDISFLFGPKKRLEML 246
>5hl3_A A Lmo2470 protein
Length=409
Score = 38.1 bits (87), Expect = 0.38, Method: Compositional matrix adjust.
Identities = 42/145 (29%), Positives = 63/145 (43%), Gaps = 17/145 (12%)
Query 444 GQELTGQ--EWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP 501
G L G ++ G+ + ++Y+S +F +P L L L L +
Sbjct 132 GNNLIGSIPDFTGMPALKQLYMSEMLITSDELPNFNNIPLLITLDLSSNQLTTIPD---- 187
Query 502 FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGL 561
FQ + NLT LDL+ N + N D + L KL L+L+HNNL G + L
Sbjct 188 FQNIPNLTFLDLNANLLTNTPD--FQNLPKLTDLNLRHNNLT---------GTMVNYTNL 236
Query 562 SHLHILNLESNGFDEIPVEVFKDLF 586
L LNL+ N E+P V ++
Sbjct 237 PSLESLNLDYNFLTELPSNVLDTIY 261
>5gr8_B D Leucine-rich repeat receptor-like protein kinase PEPR1
Length=710
Score = 38.5 bits (88), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 150/618 (24%), Positives = 235/618 (38%), Gaps = 76/618 (12%)
Query 58 LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDK 117
+T + + + + NFTR S+++ +L PE+ + L L++L+L N S
Sbjct 41 ITCDDSKNVASLNFTR-SRVSG---------QLGPEIGE-LKSLQILDLSTNNFSGTIPS 89
Query 118 TFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELL 177
T CT L L L N + K L L L N L+ + ++ LQ L
Sbjct 90 TLGNCTKLATLDLSENGFSDKIPDTLDSLKRLEVLYLYINFLTGELPESLFRIPKLQVLY 149
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSL 237
L N + + I L +L + +NQ P L L+L+ +L SL
Sbjct 150 LDYNNLTGPIPQS--IGDAKELVELSMYANQFSGNIPESIGNSSSLQILYLHRNKLVGSL 207
Query 238 TEKLCLELANTS--IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
E L L T+ + N SL F NL LDLSYN +
Sbjct 208 PESLNLLGNLTTLFVGNNSLQGP-------VRFGSPNCKNLLTLDLSYNEFEGGVPPALG 260
Query 296 WLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI-------SLASLPKIDD 348
L+ + N+ SL L N+ LNL + SI S +L K++D
Sbjct 261 NCSSLDALVIVSGNLSGTIPSSLGMLKNLTILNLSENRLSGSIPAELGNCSSLNLLKLND 320
Query 349 --------FSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
+ L+ LE L + +N F+G I ++ S S T L N
Sbjct 321 NQLVGGIPSALGKLRKLESLELFEN--------RFSGEIPIEIWK-SQSLTQLLVYQNNL 371
Query 401 FVSLAHSPLHILNLTKNKISKIESDAF-----SWLG---HLEVLDLGLNEIGQELTGQEW 452
L P+ + + K KI+ + +++F LG LE +D IG +LTG+
Sbjct 372 TGEL---PVEMTEMKKLKIATLFNNSFYGAIPPGLGVNSSLEEVDF----IGNKLTGEIP 424
Query 453 RGL---ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLT 509
L + + L N S +++R +LR N+ F +L+
Sbjct 425 PNLCHGRKLRILNLGSNLLHGTIPASIGHCKTIRRFILRE---NNLSGLLPEFSQDHSLS 481
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
LD ++NN L + L ++L N R P L L +L +NL
Sbjct 482 FLDFNSNNFEGPIPGSLGSCKNLSSINLSRN---RFTGQIPP-----QLGNLQNLGYMNL 533
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
N + + L+ D+G N+LN S F+N L +L L +N + +
Sbjct 534 SRNLLEGSLPAQLSNCVSLERFDVGFNSLNGSVPSNFSNWKGLTTLVLSENRFSGGIPQ- 592
Query 630 FGPAFRNLTELDMRFNPF 647
F P + L+ L + N F
Sbjct 593 FLPELKKLSTLQIARNAF 610
Score = 34.7 bits (78), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 117/489 (24%), Positives = 198/489 (40%), Gaps = 62/489 (13%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
L L+L +NE C++L L ++S ++ + KNL L+LS N LS
Sbjct 241 LLTLDLSYNEFEGGVPPALGNCSSLDALVIVSGNLSGTIPSSLGMLKNLTILNLSENRLS 300
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCF--- 217
+ +L L L++N++ L L+ LEL N+ P
Sbjct 301 GSIPAELGNCSSLNLLKLNDNQLVGGIPSALGKLR--KLESLELFENRFSGEIPIEIWKS 358
Query 218 HAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLT 277
++ +L ++ NN LT +L +E+ T ++ L +++T N +F G L
Sbjct 359 QSLTQLL-VYQNN------LTGELPVEM--TEMKKL-----KIATLFNNSFYGAIPPGLG 404
Query 278 MLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF--NVRYLNLKRSFTK 335
+ + S ++ +GN +P I +L S+ LHG ++ + R F
Sbjct 405 V-NSSLEEVDFIGNKLTGEIPP-NLCHGRKLRILNLGSNLLHGTIPASIGHCKTIRRFIL 462
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTS-- 392
+ +L+ L + +FS L L+ N+ G NL ++LS N FT
Sbjct 463 RENNLSGL--LPEFSQD--HSLSFLDFNSNNFEGPIPGSLGSCKNLSSINLSRNRFTGQI 518
Query 393 ---LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTG 449
L L N L +NL++N + S LE D+G N + +
Sbjct 519 PPQLGNLQN----------LGYMNLSRNLLEGSLPAQLSNCVSLERFDVGFNSLNGSVPS 568
Query 450 --QEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS-PSPFQPLR 506
W+GL + LS N++ + +P L++L ++A PS +
Sbjct 569 NFSNWKGLTTLV---LSENRF---SGGIPQFLPELKKLSTLQIARNAFGGEIPSSIGLIE 622
Query 507 NLTI-LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
+L LDLS N + L L KL L++ +NNL G + LKGL+ L
Sbjct 623 DLIYDLDLSGNGLTGEIPAKLGDLIKLTRLNISNNNLT---------GSLSVLKGLTSLL 673
Query 566 ILNLESNGF 574
+++ +N F
Sbjct 674 HVDVSNNQF 682
>5gr8_A A Leucine-rich repeat receptor-like protein kinase PEPR1
Length=710
Score = 38.5 bits (88), Expect = 0.39, Method: Compositional matrix adjust.
Identities = 150/618 (24%), Positives = 235/618 (38%), Gaps = 76/618 (12%)
Query 58 LTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDK 117
+T + + + + NFTR S+++ +L PE+ + L L++L+L N S
Sbjct 41 ITCDDSKNVASLNFTR-SRVSG---------QLGPEIGE-LKSLQILDLSTNNFSGTIPS 89
Query 118 TFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQELL 177
T CT L L L N + K L L L N L+ + ++ LQ L
Sbjct 90 TLGNCTKLATLDLSENGFSDKIPDTLDSLKRLEVLYLYINFLTGELPESLFRIPKLQVLY 149
Query 178 LSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSL 237
L N + + I L +L + +NQ P L L+L+ +L SL
Sbjct 150 LDYNNLTGPIPQS--IGDAKELVELSMYANQFSGNIPESIGNSSSLQILYLHRNKLVGSL 207
Query 238 TEKLCLELANTS--IRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNVVGNDSFA 295
E L L T+ + N SL F NL LDLSYN +
Sbjct 208 PESLNLLGNLTTLFVGNNSLQGP-------VRFGSPNCKNLLTLDLSYNEFEGGVPPALG 260
Query 296 WLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSI-------SLASLPKIDD 348
L+ + N+ SL L N+ LNL + SI S +L K++D
Sbjct 261 NCSSLDALVIVSGNLSGTIPSSLGMLKNLTILNLSENRLSGSIPAELGNCSSLNLLKLND 320
Query 349 --------FSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLSNSFTSLRTLTNET 400
+ L+ LE L + +N F+G I ++ S S T L N
Sbjct 321 NQLVGGIPSALGKLRKLESLELFEN--------RFSGEIPIEIWK-SQSLTQLLVYQNNL 371
Query 401 FVSLAHSPLHILNLTKNKISKIESDAF-----SWLG---HLEVLDLGLNEIGQELTGQEW 452
L P+ + + K KI+ + +++F LG LE +D IG +LTG+
Sbjct 372 TGEL---PVEMTEMKKLKIATLFNNSFYGAIPPGLGVNSSLEEVDF----IGNKLTGEIP 424
Query 453 RGL---ENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSPFQPLRNLT 509
L + + L N S +++R +LR N+ F +L+
Sbjct 425 PNLCHGRKLRILNLGSNLLHGTIPASIGHCKTIRRFILRE---NNLSGLLPEFSQDHSLS 481
Query 510 ILDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNL 569
LD ++NN L + L ++L N R P L L +L +NL
Sbjct 482 FLDFNSNNFEGPIPGSLGSCKNLSSINLSRN---RFTGQIPP-----QLGNLQNLGYMNL 533
Query 570 ESNGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKV 629
N + + L+ D+G N+LN S F+N L +L L +N + +
Sbjct 534 SRNLLEGSLPAQLSNCVSLERFDVGFNSLNGSVPSNFSNWKGLTTLVLSENRFSGGIPQ- 592
Query 630 FGPAFRNLTELDMRFNPF 647
F P + L+ L + N F
Sbjct 593 FLPELKKLSTLQIARNAF 610
Score = 34.7 bits (78), Expect = 6.2, Method: Compositional matrix adjust.
Identities = 117/489 (24%), Positives = 198/489 (40%), Gaps = 62/489 (13%)
Query 101 LKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLS 160
L L+L +NE C++L L ++S ++ + KNL L+LS N LS
Sbjct 241 LLTLDLSYNEFEGGVPPALGNCSSLDALVIVSGNLSGTIPSSLGMLKNLTILNLSENRLS 300
Query 161 STKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCF--- 217
+ +L L L++N++ L L+ LEL N+ P
Sbjct 301 GSIPAELGNCSSLNLLKLNDNQLVGGIPSALGKLR--KLESLELFENRFSGEIPIEIWKS 358
Query 218 HAIGRLFGLFLNNVQLGPSLTEKLCLELANTSIRNLSLSNSQLSTTSNTTFLGLKWTNLT 277
++ +L ++ NN LT +L +E+ T ++ L +++T N +F G L
Sbjct 359 QSLTQLL-VYQNN------LTGELPVEM--TEMKKL-----KIATLFNNSFYGAIPPGLG 404
Query 278 MLDLSYNNLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLF--NVRYLNLKRSFTK 335
+ + S ++ +GN +P I +L S+ LHG ++ + R F
Sbjct 405 V-NSSLEEVDFIGNKLTGEIPP-NLCHGRKLRILNLGSNLLHGTIPASIGHCKTIRRFIL 462
Query 336 QSISLASLPKIDDFSFQWLKCLEHLNMEDNDIPGIKSNMFTGLINLKYLSLS-NSFTS-- 392
+ +L+ L + +FS L L+ N+ G NL ++LS N FT
Sbjct 463 RENNLSGL--LPEFSQD--HSLSFLDFNSNNFEGPIPGSLGSCKNLSSINLSRNRFTGQI 518
Query 393 ---LRTLTNETFVSLAHSPLHILNLTKNKISKIESDAFSWLGHLEVLDLGLNEIGQELTG 449
L L N L +NL++N + S LE D+G N + +
Sbjct 519 PPQLGNLQN----------LGYMNLSRNLLEGSLPAQLSNCVSLERFDVGFNSLNGSVPS 568
Query 450 --QEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSS-PSPFQPLR 506
W+GL + LS N++ + +P L++L ++A PS +
Sbjct 569 NFSNWKGLTTLV---LSENRF---SGGIPQFLPELKKLSTLQIARNAFGGEIPSSIGLIE 622
Query 507 NLTI-LDLSNNNIANINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLH 565
+L LDLS N + L L KL L++ +NNL G + LKGL+ L
Sbjct 623 DLIYDLDLSGNGLTGEIPAKLGDLIKLTRLNISNNNLT---------GSLSVLKGLTSLL 673
Query 566 ILNLESNGF 574
+++ +N F
Sbjct 674 HVDVSNNQF 682
>4pbw_C C NT-3 growth factor receptor
Length=283
Score = 37.0 bits (84), Expect = 0.83, Method: Compositional matrix adjust.
Identities = 29/121 (24%), Positives = 57/121 (47%), Gaps = 11/121 (9%)
Query 559 KGLSHLHILNLES-NGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
+ ++ +HI N ++ + + +E++ L L I + GL N+ F L+ ++L
Sbjct 50 RNITSIHIENWKNLQTLNAVDMELYTGLQRLTIRNSGLRNIQ---PRAFAKNPHLRYIDL 106
Query 618 QKNLITSVEKKVFGPAFRNLTELDMRF--NPFDCTCESIAWFVNWINETHTNIPELSSHY 675
N +T++ ++F + L D+R NPF C+C+ I W W + N+ H
Sbjct 107 SGNRLTTLSWQLF----QTLRLFDLRLERNPFQCSCD-IRWIQLWQEKGEANLQSQQLHC 161
Query 676 L 676
+
Sbjct 162 M 162
>4pbw_B A NT-3 growth factor receptor
Length=283
Score = 37.0 bits (84), Expect = 0.86, Method: Compositional matrix adjust.
Identities = 29/121 (24%), Positives = 57/121 (47%), Gaps = 11/121 (9%)
Query 559 KGLSHLHILNLES-NGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
+ ++ +HI N ++ + + +E++ L L I + GL N+ F L+ ++L
Sbjct 50 RNITSIHIENWKNLQTLNAVDMELYTGLQRLTIRNSGLRNIQ---PRAFAKNPHLRYIDL 106
Query 618 QKNLITSVEKKVFGPAFRNLTELDMRF--NPFDCTCESIAWFVNWINETHTNIPELSSHY 675
N +T++ ++F + L D+R NPF C+C+ I W W + N+ H
Sbjct 107 SGNRLTTLSWQLF----QTLRLFDLRLERNPFQCSCD-IRWIQLWQEKGEANLQSQQLHC 161
Query 676 L 676
+
Sbjct 162 M 162
>4pbv_A A NT-3 growth factor receptor
Length=268
Score = 36.6 bits (83), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 29/119 (24%), Positives = 57/119 (48%), Gaps = 7/119 (6%)
Query 559 KGLSHLHILNLES-NGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
+ ++ +HI N ++ + + +E++ L L I + GL N+ F L+ ++L
Sbjct 35 RNITSIHIENWKNLQTLNAVDMELYTGLQRLTIRNSGLRNIQ---PRAFAKNPHLRYIDL 91
Query 618 QKNLITSVEKKVFGPAFRNLTELDMRFNPFDCTCESIAWFVNWINETHTNIPELSSHYL 676
N +T++ ++F R L +L + NPF C+C+ I W W + N+ H +
Sbjct 92 SGNRLTTLSWQLF-QTLR-LFDLRLERNPFQCSCD-IRWIQLWQEKGEANLQSQQLHCM 147
>4pbv_B B NT-3 growth factor receptor
Length=268
Score = 36.6 bits (83), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 29/121 (24%), Positives = 57/121 (47%), Gaps = 11/121 (9%)
Query 559 KGLSHLHILNLES-NGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
+ ++ +HI N ++ + + +E++ L L I + GL N+ F L+ ++L
Sbjct 35 RNITSIHIENWKNLQTLNAVDMELYTGLQRLTIRNSGLRNIQ---PRAFAKNPHLRYIDL 91
Query 618 QKNLITSVEKKVFGPAFRNLTELDMRF--NPFDCTCESIAWFVNWINETHTNIPELSSHY 675
N +T++ ++F + L D+R NPF C+C+ I W W + N+ H
Sbjct 92 SGNRLTTLSWQLF----QTLRLFDLRLERNPFQCSCD-IRWIQLWQEKGEANLQSQQLHC 146
Query 676 L 676
+
Sbjct 147 M 147
>4pbw_A B NT-3 growth factor receptor
Length=283
Score = 36.6 bits (83), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 29/121 (24%), Positives = 57/121 (47%), Gaps = 11/121 (9%)
Query 559 KGLSHLHILNLES-NGFDEIPVEVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNL 617
+ ++ +HI N ++ + + +E++ L L I + GL N+ F L+ ++L
Sbjct 50 RNITSIHIENWKNLQTLNAVDMELYTGLQRLTIRNSGLRNIQ---PRAFAKNPHLRYIDL 106
Query 618 QKNLITSVEKKVFGPAFRNLTELDMRF--NPFDCTCESIAWFVNWINETHTNIPELSSHY 675
N +T++ ++F + L D+R NPF C+C+ I W W + N+ H
Sbjct 107 SGNRLTTLSWQLF----QTLRLFDLRLERNPFQCSCD-IRWIQLWQEKGEANLQSQQLHC 161
Query 676 L 676
+
Sbjct 162 M 162
>6tme_B B Pollen-specific leucine-rich repeat extensin-like protein
1
Length=372
Score = 36.6 bits (83), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 4/137 (3%)
Query 56 LNLTHNQLR-RLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
L++ +N +LP F + L ++ + N PE K V+ HN+ S
Sbjct 169 LDIRYNDFEGKLPPEIFDK--DLDAIFLNNNRFESTIPETIGK-STASVVTFAHNKFSGC 225
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
KT NL E+ + N++ N N+ D S NG + T L N++
Sbjct 226 IPKTIGQMKNLNEIVFIGNNLSGCLPNEIGSLNNVTVFDASSNGFVGSLPSTLSGLANVE 285
Query 175 ELLLSNNKIQALKSEEL 191
++ S NK ++ +
Sbjct 286 QMDFSYNKFTGFVTDNI 302
>6tme_A A Pollen-specific leucine-rich repeat extensin-like protein
1
Length=372
Score = 36.6 bits (83), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 4/137 (3%)
Query 56 LNLTHNQLR-RLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
L++ +N +LP F + L ++ + N PE K V+ HN+ S
Sbjct 169 LDIRYNDFEGKLPPEIFDK--DLDAIFLNNNRFESTIPETIGK-STASVVTFAHNKFSGC 225
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
KT NL E+ + N++ N N+ D S NG + T L N++
Sbjct 226 IPKTIGQMKNLNEIVFIGNNLSGCLPNEIGSLNNVTVFDASSNGFVGSLPSTLSGLANVE 285
Query 175 ELLLSNNKIQALKSEEL 191
++ S NK ++ +
Sbjct 286 QMDFSYNKFTGFVTDNI 302
>6qwn_E C Pollen-specific leucine-rich repeat extensin-like protein
1
Length=379
Score = 36.6 bits (83), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 4/137 (3%)
Query 56 LNLTHNQLR-RLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
L++ +N +LP F + L ++ + N PE K V+ HN+ S
Sbjct 169 LDIRYNDFEGKLPPEIFDK--DLDAIFLNNNRFESTIPETIGK-STASVVTFAHNKFSGC 225
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
KT NL E+ + N++ N N+ D S NG + T L N++
Sbjct 226 IPKTIGQMKNLNEIVFIGNNLSGCLPNEIGSLNNVTVFDASSNGFVGSLPSTLSGLANVE 285
Query 175 ELLLSNNKIQALKSEEL 191
++ S NK ++ +
Sbjct 286 QMDFSYNKFTGFVTDNI 302
>4tzh_B B LIC12234
Length=190
Score = 35.8 bits (81), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 50/177 (28%), Positives = 80/177 (45%), Gaps = 22/177 (12%)
Query 467 KYLQLTRNSFALVP-------SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
+ L L+RN ++P +L+ L LR L + P L+NL LD+S N I+
Sbjct 21 QILDLSRNQLTILPKEIEQLVNLESLHLRDNELTTL---PEEIGILKNLKYLDISRNQIS 77
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
N ++ + L+ LE+L L N+L+ L + + L L IL L +N +P
Sbjct 78 NFPKEI-QKLKNLEVLFLNGNSLSNLPEE---------IGELEKLGILYLNNNQLTTLPK 127
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN 636
E+ + L L + L N L ++P L+ LNL N + ++ FRN
Sbjct 128 EIGQ-LENLVSLSLSSNKLTSIPDE-LGQLKKLRILNLWDNPTLTTPERNIRKLFRN 182
Score = 35.0 bits (79), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 46/141 (33%), Positives = 70/141 (50%), Gaps = 7/141 (5%)
Query 50 PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHN 109
P + +L+L+ NQL LP + L SL + N ++ L PE L LK L++ N
Sbjct 17 PNEVQILDLSRNQLTILPKE-IEQLVNLESLHLRDNELTTL-PEEIGILKNLKYLDISRN 74
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV- 168
++S K NL L L NS+ + + + L L L++N L T L ++
Sbjct 75 QISNFP-KEIQKLKNLEVLFLNGNSLSNLPEE-IGELEKLGILYLNNNQL--TTLPKEIG 130
Query 169 QLENLQELLLSNNKIQALKSE 189
QLENL L LS+NK+ ++ E
Sbjct 131 QLENLVSLSLSSNKLTSIPDE 151
>4fmz_B B Internalin
Length=371
Score = 36.6 bits (83), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 84/317 (26%), Positives = 140/317 (44%), Gaps = 58/317 (18%)
Query 51 TNITVLNLTHNQLRRL-PAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHN 109
TN+ LNL NQ+ + P +N + LT+L +G N I+ + LQ+
Sbjct 66 TNLEYLNLNGNQITDISPLSNLVK---LTNLYIGTNKITDISA-------------LQN- 108
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
TNL EL+L ++I I P + +L+L N + + L
Sbjct 109 ------------LTNLRELYLNEDNISDIS--PLANLTKMYSLNLGANH-NLSDLSPLSN 153
Query 170 LENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+ L L ++ +K++ ++ AN + L L L+ NQI++ SP F ++
Sbjct 154 MTGLNYLTVTESKVK-----DVTPIANLTDLYSLSLNYNQIEDISPLASLTSLHYFTAYV 208
Query 229 NNV-QLGP--SLTEKLCLELANTSIRNLS-LSN-SQLS-----TTSNTTFLGLK-WTNLT 277
N + + P ++T L++ N I +LS L+N SQL+ T + +K T L
Sbjct 209 NQITDITPVANMTRLNSLKIGNNKITDLSPLANLSQLTWLEIGTNQISDINAVKDLTKLK 268
Query 278 MLDLSYN---NLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
ML++ N +++V+ N L QL FL N + + + GL N+ L L ++
Sbjct 269 MLNVGSNQISDISVLNN-----LSQLNSLFLNNNQLGNEDMEVIGGLTNLTTLFLSQNHI 323
Query 335 KQSISLASLPKIDDFSF 351
LASL K+D F
Sbjct 324 TDIRPLASLSKMDSADF 340
>6qwn_G D Pollen-specific leucine-rich repeat extensin-like protein
1
Length=379
Score = 36.6 bits (83), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 4/137 (3%)
Query 56 LNLTHNQLR-RLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
L++ +N +LP F + L ++ + N PE K V+ HN+ S
Sbjct 169 LDIRYNDFEGKLPPEIFDK--DLDAIFLNNNRFESTIPETIGK-STASVVTFAHNKFSGC 225
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
KT NL E+ + N++ N N+ D S NG + T L N++
Sbjct 226 IPKTIGQMKNLNEIVFIGNNLSGCLPNEIGSLNNVTVFDASSNGFVGSLPSTLSGLANVE 285
Query 175 ELLLSNNKIQALKSEEL 191
++ S NK ++ +
Sbjct 286 QMDFSYNKFTGFVTDNI 302
>6qwn_C B Pollen-specific leucine-rich repeat extensin-like protein
1
Length=379
Score = 36.6 bits (83), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 4/137 (3%)
Query 56 LNLTHNQLR-RLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
L++ +N +LP F + L ++ + N PE K V+ HN+ S
Sbjct 169 LDIRYNDFEGKLPPEIFDK--DLDAIFLNNNRFESTIPETIGK-STASVVTFAHNKFSGC 225
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
KT NL E+ + N++ N N+ D S NG + T L N++
Sbjct 226 IPKTIGQMKNLNEIVFIGNNLSGCLPNEIGSLNNVTVFDASSNGFVGSLPSTLSGLANVE 285
Query 175 ELLLSNNKIQALKSEEL 191
++ S NK ++ +
Sbjct 286 QMDFSYNKFTGFVTDNI 302
>6qwn_A A Pollen-specific leucine-rich repeat extensin-like protein
1
Length=379
Score = 36.6 bits (83), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 4/137 (3%)
Query 56 LNLTHNQLR-RLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
L++ +N +LP F + L ++ + N PE K V+ HN+ S
Sbjct 169 LDIRYNDFEGKLPPEIFDK--DLDAIFLNNNRFESTIPETIGK-STASVVTFAHNKFSGC 225
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
KT NL E+ + N++ N N+ D S NG + T L N++
Sbjct 226 IPKTIGQMKNLNEIVFIGNNLSGCLPNEIGSLNNVTVFDASSNGFVGSLPSTLSGLANVE 285
Query 175 ELLLSNNKIQALKSEEL 191
++ S NK ++ +
Sbjct 286 QMDFSYNKFTGFVTDNI 302
>4tzh_A A LIC12234
Length=190
Score = 35.4 bits (80), Expect = 1.4, Method: Compositional matrix adjust.
Identities = 50/177 (28%), Positives = 80/177 (45%), Gaps = 22/177 (12%)
Query 467 KYLQLTRNSFALVP-------SLQRLMLRRVALKNVDSSPSPFQPLRNLTILDLSNNNIA 519
+ L L+RN ++P +L+ L LR L + P L+NL LD+S N I+
Sbjct 21 QILDLSRNQLTILPKEIEQLVNLESLHLRDNELTTL---PEEIGILKNLKYLDISRNQIS 77
Query 520 NINDDMLEGLEKLEILDLQHNNLARLWKHANPGGPIYFLKGLSHLHILNLESNGFDEIPV 579
N ++ + L+ LE+L L N+L+ L + + L L IL L +N +P
Sbjct 78 NFPKEI-QKLKNLEVLFLNGNSLSNLPEE---------IGELEKLGILYLNNNQLTTLPK 127
Query 580 EVFKDLFELKIIDLGLNNLNTLPASVFNNQVSLKSLNLQKNLITSVEKKVFGPAFRN 636
E+ + L L + L N L ++P L+ LNL N + ++ FRN
Sbjct 128 EIGQ-LENLVSLSLSSNKLTSIPDE-LGQLKKLRILNLWDNPTLTTPERNIRKLFRN 182
Score = 35.0 bits (79), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 46/141 (33%), Positives = 70/141 (50%), Gaps = 7/141 (5%)
Query 50 PTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHN 109
P + +L+L+ NQL LP + L SL + N ++ L PE L LK L++ N
Sbjct 17 PNEVQILDLSRNQLTILPKE-IEQLVNLESLHLRDNELTTL-PEEIGILKNLKYLDISRN 74
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQV- 168
++S K NL L L NS+ + + + L L L++N L T L ++
Sbjct 75 QISNFP-KEIQKLKNLEVLFLNGNSLSNLPEE-IGELEKLGILYLNNNQL--TTLPKEIG 130
Query 169 QLENLQELLLSNNKIQALKSE 189
QLENL L LS+NK+ ++ E
Sbjct 131 QLENLVSLSLSSNKLTSIPDE 151
>8e04_A A Leucine-rich repeat serine/threonine-protein kinase
1
Length=1996
Score = 36.6 bits (83), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 39/135 (29%), Positives = 59/135 (44%), Gaps = 7/135 (5%)
Query 76 QLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSI 135
+L LD+ N +++L L LN+ N L D + L N++
Sbjct 362 KLQELDISDNKLTELPALFLHSFKSLNSLNVSRNNLKVFPD---PWACPLKCCKASRNAL 418
Query 136 QKIKNNPFVKQKN-LITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIF 194
+ + + V KN L +D S N L LG QL+ L L L N++ AL +E +
Sbjct 419 ECLPDKMAVFWKNHLKDVDFSENALKEVPLGL-FQLDALMFLRLQGNQLAALPPQEK--W 475
Query 195 ANSSLKKLELSSNQI 209
LK L+LS NQ+
Sbjct 476 TCRQLKTLDLSRNQL 490
>4fmz_A A Internalin
Length=371
Score = 36.2 bits (82), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 86/320 (27%), Positives = 143/320 (45%), Gaps = 60/320 (19%)
Query 51 TNITVLNLTHNQLRRL-PAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHN 109
TN+ LNL NQ+ + P +N + LT+L +G N I+ + LQ+
Sbjct 66 TNLEYLNLNGNQITDISPLSNLVK---LTNLYIGTNKITDISA-------------LQN- 108
Query 110 ELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQ 169
TNL EL+L ++I I P + +L+L N + + L
Sbjct 109 ------------LTNLRELYLNEDNISDIS--PLANLTKMYSLNLGANH-NLSDLSPLSN 153
Query 170 LENLQELLLSNNKIQALKSEELDIFAN-SSLKKLELSSNQIKEFSPGCFHAIGRLFGLFL 228
+ L L ++ +K++ ++ AN + L L L+ NQI++ SP F ++
Sbjct 154 MTGLNYLTVTESKVK-----DVTPIANLTDLYSLSLNYNQIEDISPLASLTSLHYFTAYV 208
Query 229 NNV-QLGP--SLTEKLCLELANTSIRNLS-LSN-SQLS-----TTSNTTFLGLK-WTNLT 277
N + + P ++T L++ N I +LS L+N SQL+ T + +K T L
Sbjct 209 NQITDITPVANMTRLNSLKIGNNKITDLSPLANLSQLTWLEIGTNQISDINAVKDLTKLK 268
Query 278 MLDLSYN---NLNVVGNDSFAWLPQLEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFT 334
ML++ N +++V+ N L QL FL N + + + GL N+ L L ++
Sbjct 269 MLNVGSNQISDISVLNN-----LSQLNSLFLNNNQLGNEDMEVIGGLTNLTTLFLSQNHI 323
Query 335 KQSISLASLPKID--DFSFQ 352
LASL K+D DF+ Q
Sbjct 324 TDIRPLASLSKMDSADFANQ 343
>7utz_D R Thyrotropin receptor
Length=701
Score = 36.2 bits (82), Expect = 1.8, Method: Compositional matrix adjust.
Identities = 48/205 (23%), Positives = 84/205 (41%), Gaps = 54/205 (26%)
Query 18 GMLCASSTTKCTVSHEVAD----CSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTR 73
GM C+S +C H+ D C ++ ++P LP + L L LR +P+ F+
Sbjct 8 GMGCSSPPCEC---HQEEDFRVTCKDIQ--RIPS-LPPSTQTLKLIETHLRTIPSHAFSN 61
Query 74 YSQLT----SLDV--------GFNTISK--------------LEPELCQKLPMLKVLNLQ 107
++ S+DV F +SK ++P+ ++LP+LK L +
Sbjct 62 LPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALKELPLLKFLGIF 121
Query 108 HNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQ----------KNLITLDLSHN 157
+ L D T + T++ I +I +NP++ +TL L +N
Sbjct 122 NTGLKMFPDLTKVYSTDIF-------FILEITDNPYMTSIPVNAFQGLCNETLTLKLYNN 174
Query 158 GLSSTKLGTQVQLENLQELLLSNNK 182
G +S + G L + L+ NK
Sbjct 175 GFTSVQ-GYAFNGTKLDAVYLNKNK 198
>1g9u_A A OUTER PROTEIN YOPM
Length=454
Score = 35.8 bits (81), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 30/96 (31%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
Query 48 DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQ 107
DLP + L +++NQL +LP + + L +DV N++ KL P+L L + N Q
Sbjct 128 DLPPLLEYLGVSNNQLEKLPELQNSSF--LKIIDVDNNSLKKL-PDLPPSLEFIAAGNNQ 184
Query 108 HNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
EL +L + F LT ++ +NS++K+ + P
Sbjct 185 LEELPELQNLPF-----LTAIYADNNSLKKLPDLPL 215
>1jl5_A A outer protein YopM
Length=454
Score = 35.8 bits (81), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 30/96 (31%), Positives = 51/96 (53%), Gaps = 8/96 (8%)
Query 48 DLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQ 107
DLP + L +++NQL +LP + + L +DV N++ KL P+L L + N Q
Sbjct 128 DLPPLLEYLGVSNNQLEKLPELQNSSF--LKIIDVDNNSLKKL-PDLPPSLEFIAAGNNQ 184
Query 108 HNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPF 143
EL +L + F LT ++ +NS++K+ + P
Sbjct 185 LEELPELQNLPF-----LTAIYADNNSLKKLPDLPL 215
>3twi_F F Variable lymphocyte receptor B
Length=179
Score = 35.0 bits (79), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 27/108 (25%), Positives = 43/108 (40%), Gaps = 0/108 (0%)
Query 26 TKCTVSHEVADCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFN 85
++C+ S +C L VP PT VL+L NQ+ LT L++ N
Sbjct 15 SQCSCSXXTVNCQXRSLXSVPXXXPTXXXVLHLYINQITXXXPGVXXXXXXLTYLNLAVN 74
Query 86 TISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSN 133
++ L + L L L N+L + LT ++L +N
Sbjct 75 QLTALPVGVXXXXXXLTHLALHINQLXSIPMGVXXXXXXLTHIYLFNN 122
>6qwn_I E Pollen-specific leucine-rich repeat extensin-like protein
1
Length=379
Score = 35.8 bits (81), Expect = 2.1, Method: Compositional matrix adjust.
Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 4/137 (3%)
Query 56 LNLTHNQLR-RLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQL 114
L++ +N +LP F + L ++ + N PE K V+ HN+ S
Sbjct 169 LDIRYNDFEGKLPPEIFDK--DLDAIFLNNNRFESTIPETIGK-STASVVTFAHNKFSGC 225
Query 115 SDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQLENLQ 174
KT NL E+ + N++ N N+ D S NG + T L N++
Sbjct 226 IPKTIGQMKNLNEIVFIGNNLSXXXPNEIGSLNNVTVFDASSNGFVGSLPSTLSGLANVE 285
Query 175 ELLLSNNKIQALKSEEL 191
++ S NK ++ +
Sbjct 286 QMDFSYNKFTXXVTDNI 302
>3bz5_A A Internalin-J
Length=457
Score = 35.4 bits (80), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 65/240 (27%), Positives = 110/240 (46%), Gaps = 36/240 (15%)
Query 36 DCSHLKLTQVPDDLPTNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELC 95
+C+ LT++ T +T L+ N +++ + T +QLT+LD FN I++L+
Sbjct 133 NCARNTLTEIDVSHNTQLTELDCHLN--KKITKLDVTPQTQLTTLDCSFNKITELD---V 187
Query 96 QKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLS 155
+ +L LN N +++L LT L SN + +I P + L D S
Sbjct 188 SQNKLLNRLNCDTNNITKLD---LNQNIQLTFLDCSSNKLTEIDVTPLTQ---LTYFDCS 241
Query 156 HNGLSSTKLGTQVQLENLQ-------ELLLSNNK----IQA---LKSEELDIFANSSLKK 201
N L+ + T +L L E+ L++N QA K +ELD+ N+ L
Sbjct 242 VNPLTELDVSTLSKLTTLHCIQTDLLEIDLTHNTQLIYFQAEGCRKIKELDVTHNTQLYL 301
Query 202 LELSSNQIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTEKLCLELA-NTSIRNLSLSNSQL 260
L+ + I E +L L+LNN + LTE L+++ NT +++LS N+ +
Sbjct 302 LDCQAAGITELD---LSQNPKLVYLYLNNTE----LTE---LDVSHNTKLKSLSCVNAHI 351
>4u08_B B LIC11098
Length=402
Score = 35.4 bits (80), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 99/387 (26%), Positives = 151/387 (39%), Gaps = 89/387 (23%)
Query 50 PTNITVLNLTHNQLRRLPA----------------------ANFTRYSQLTSLDVGFNTI 87
P N+ +LNL+ ++L LP + L L + N +
Sbjct 19 PQNVRILNLSGSKLTTLPGEIGKLQNLQLLNLDDNQLIALPKEIGKLQNLQQLHLSKNQL 78
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
L PE +L L+ L L N+L+ + K NL EL+L N + + + + +
Sbjct 79 MAL-PEEIGQLQNLQKLKLYENQLTAIP-KEIGQLQNLQELNLAHNQLATLPED-IEQLQ 135
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
L TL L HN +S L QL+NL+ L L +N++ L E I +L+ L L N
Sbjct 136 RLQTLYLGHNQFNSI-LKEIGQLQNLESLGLDHNQLNVLPKE---IGQLRNLESLGLDHN 191
Query 208 QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTE---------------------KLCLELA 246
Q+ P + L L L N QL E K +L
Sbjct 192 QLNVL-PKEIGQLQNLQILHLRNNQLTTLPKEIGQLQNLQKLLLNKNKLTTLPKEIGQLQ 250
Query 247 NTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV---------------VGN 291
N ++ L L +QL+T + NL LDL N L +GN
Sbjct 251 N--LQKLKLYENQLTTLPKEIG---QLQNLQELDLDGNQLTTLPENIGQLQRLQTLYLGN 305
Query 292 DSFAWLPQ-------LEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLP 344
+ +LP+ LE LE+N + L + L ++ LNLK + LA+LP
Sbjct 306 NQLNFLPKEIGQLRNLESLDLEHNQLNAL-PKEIGKLQKLQTLNLKYN------QLATLP 358
Query 345 KIDDFSFQWLKCLEHLNMEDNDIPGIK 371
+ + LK L+ L + +N +P K
Sbjct 359 E----EIKQLKNLKKLYLHNNPLPSEK 381
Score = 34.3 bits (77), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 34/118 (29%), Positives = 60/118 (51%), Gaps = 13/118 (11%)
Query 28 CTVSHEVADCSHLK--------LTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQL 77
T+ E+ +L+ LT +P+++ + L L +NQL LP + L
Sbjct 263 TTLPKEIGQLQNLQELDLDGNQLTTLPENIGQLQRLQTLYLGNNQLNFLPKE-IGQLRNL 321
Query 78 TSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSI 135
SLD+ N ++ L E+ KL L+ LNL++N+L+ L ++ NL +L+L +N +
Sbjct 322 ESLDLEHNQLNALPKEIG-KLQKLQTLNLKYNQLATLPEE-IKQLKNLKKLYLHNNPL 377
>4u08_A A LIC11098
Length=402
Score = 35.4 bits (80), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 99/387 (26%), Positives = 151/387 (39%), Gaps = 89/387 (23%)
Query 50 PTNITVLNLTHNQLRRLPA----------------------ANFTRYSQLTSLDVGFNTI 87
P N+ +LNL+ ++L LP + L L + N +
Sbjct 19 PQNVRILNLSGSKLTTLPGEIGKLQNLQLLNLDDNQLIALPKEIGKLQNLQQLHLSKNQL 78
Query 88 SKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQK 147
L PE +L L+ L L N+L+ + K NL EL+L N + + + + +
Sbjct 79 MAL-PEEIGQLQNLQKLKLYENQLTAIP-KEIGQLQNLQELNLAHNQLATLPED-IEQLQ 135
Query 148 NLITLDLSHNGLSSTKLGTQVQLENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSN 207
L TL L HN +S L QL+NL+ L L +N++ L E I +L+ L L N
Sbjct 136 RLQTLYLGHNQFNSI-LKEIGQLQNLESLGLDHNQLNVLPKE---IGQLRNLESLGLDHN 191
Query 208 QIKEFSPGCFHAIGRLFGLFLNNVQLGPSLTE---------------------KLCLELA 246
Q+ P + L L L N QL E K +L
Sbjct 192 QLNVL-PKEIGQLQNLQILHLRNNQLTTLPKEIGQLQNLQKLLLNKNKLTTLPKEIGQLQ 250
Query 247 NTSIRNLSLSNSQLSTTSNTTFLGLKWTNLTMLDLSYNNLNV---------------VGN 291
N ++ L L +QL+T + NL LDL N L +GN
Sbjct 251 N--LQKLKLYENQLTTLPKEIG---QLQNLQELDLDGNQLTTLPENIGQLQRLQTLYLGN 305
Query 292 DSFAWLPQ-------LEYFFLEYNNIQHLFSHSLHGLFNVRYLNLKRSFTKQSISLASLP 344
+ +LP+ LE LE+N + L + L ++ LNLK + LA+LP
Sbjct 306 NQLNFLPKEIGQLRNLESLDLEHNQLNAL-PKEIGKLQKLQTLNLKYN------QLATLP 358
Query 345 KIDDFSFQWLKCLEHLNMEDNDIPGIK 371
+ + LK L+ L + +N +P K
Sbjct 359 E----EIKQLKNLKKLYLHNNPLPSEK 381
Score = 34.3 bits (77), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 34/118 (29%), Positives = 60/118 (51%), Gaps = 13/118 (11%)
Query 28 CTVSHEVADCSHLK--------LTQVPDDLPT--NITVLNLTHNQLRRLPAANFTRYSQL 77
T+ E+ +L+ LT +P+++ + L L +NQL LP + L
Sbjct 263 TTLPKEIGQLQNLQELDLDGNQLTTLPENIGQLQRLQTLYLGNNQLNFLPKE-IGQLRNL 321
Query 78 TSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSI 135
SLD+ N ++ L E+ KL L+ LNL++N+L+ L ++ NL +L+L +N +
Sbjct 322 ESLDLEHNQLNALPKEIG-KLQKLQTLNLKYNQLATLPEE-IKQLKNLKKLYLHNNPL 377
>4ow2_D D Yop effector YopM
Length=448
Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 41/130 (32%), Positives = 56/130 (43%), Gaps = 28/130 (22%)
Query 48 DLPTNITVLNLTHNQLRRLPA---------ANFTRYSQLTS-------LDVGFNTISKLE 91
DLP ++ LN+ NQL LPA A+F ++L LD N IS
Sbjct 257 DLPPSLVDLNVRKNQLIELPALPPDLERLIASFNHLAELPELPPNLSYLDASRNEISS-- 314
Query 92 PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
LC P L LN++ N+L +L A +L L N + ++ P NL
Sbjct 315 --LCDLPPSLVDLNVRKNQLIELP----ALPPDLERLIASFNHLAELPELP----PNLSY 364
Query 152 LDLSHNGLSS 161
LD S N +SS
Sbjct 365 LDASRNEISS 374
Score = 34.3 bits (77), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 56/130 (43%), Gaps = 28/130 (22%)
Query 48 DLPTNITVLNLTHNQLRRLPA---------ANFTRYSQLTS-------LDVGFNTISKLE 91
DLP ++ L++ NQL LPA A+F ++L LD N IS
Sbjct 197 DLPPSLVYLDVRDNQLIELPALPSGLERLIASFNHLAELPELPPNLYYLDASRNEISS-- 254
Query 92 PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
LC P L LN++ N+L +L A +L L N + ++ P NL
Sbjct 255 --LCDLPPSLVDLNVRKNQLIELP----ALPPDLERLIASFNHLAELPELP----PNLSY 304
Query 152 LDLSHNGLSS 161
LD S N +SS
Sbjct 305 LDASRNEISS 314
>4ow2_A A Yop effector YopM
Length=448
Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 41/130 (32%), Positives = 56/130 (43%), Gaps = 28/130 (22%)
Query 48 DLPTNITVLNLTHNQLRRLPA---------ANFTRYSQLTS-------LDVGFNTISKLE 91
DLP ++ LN+ NQL LPA A+F ++L LD N IS
Sbjct 257 DLPPSLVDLNVRKNQLIELPALPPDLERLIASFNHLAELPELPPNLSYLDASRNEISS-- 314
Query 92 PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
LC P L LN++ N+L +L A +L L N + ++ P NL
Sbjct 315 --LCDLPPSLVDLNVRKNQLIELP----ALPPDLERLIASFNHLAELPELP----PNLSY 364
Query 152 LDLSHNGLSS 161
LD S N +SS
Sbjct 365 LDASRNEISS 374
Score = 34.3 bits (77), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 56/130 (43%), Gaps = 28/130 (22%)
Query 48 DLPTNITVLNLTHNQLRRLPA---------ANFTRYSQLTS-------LDVGFNTISKLE 91
DLP ++ L++ NQL LPA A+F ++L LD N IS
Sbjct 197 DLPPSLVYLDVRDNQLIELPALPSGLERLIASFNHLAELPELPPNLYYLDASRNEISS-- 254
Query 92 PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
LC P L LN++ N+L +L A +L L N + ++ P NL
Sbjct 255 --LCDLPPSLVDLNVRKNQLIELP----ALPPDLERLIASFNHLAELPELP----PNLSY 304
Query 152 LDLSHNGLSS 161
LD S N +SS
Sbjct 305 LDASRNEISS 314
>4ow2_C C Yop effector YopM
Length=448
Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 41/130 (32%), Positives = 56/130 (43%), Gaps = 28/130 (22%)
Query 48 DLPTNITVLNLTHNQLRRLPA---------ANFTRYSQLTS-------LDVGFNTISKLE 91
DLP ++ LN+ NQL LPA A+F ++L LD N IS
Sbjct 257 DLPPSLVDLNVRKNQLIELPALPPDLERLIASFNHLAELPELPPNLSYLDASRNEISS-- 314
Query 92 PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
LC P L LN++ N+L +L A +L L N + ++ P NL
Sbjct 315 --LCDLPPSLVDLNVRKNQLIELP----ALPPDLERLIASFNHLAELPELP----PNLSY 364
Query 152 LDLSHNGLSS 161
LD S N +SS
Sbjct 365 LDASRNEISS 374
Score = 34.3 bits (77), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 56/130 (43%), Gaps = 28/130 (22%)
Query 48 DLPTNITVLNLTHNQLRRLPA---------ANFTRYSQLTS-------LDVGFNTISKLE 91
DLP ++ L++ NQL LPA A+F ++L LD N IS
Sbjct 197 DLPPSLVYLDVRDNQLIELPALPSGLERLIASFNHLAELPELPPNLYYLDASRNEISS-- 254
Query 92 PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
LC P L LN++ N+L +L A +L L N + ++ P NL
Sbjct 255 --LCDLPPSLVDLNVRKNQLIELP----ALPPDLERLIASFNHLAELPELP----PNLSY 304
Query 152 LDLSHNGLSS 161
LD S N +SS
Sbjct 305 LDASRNEISS 314
>4ow2_B B Yop effector YopM
Length=448
Score = 35.4 bits (80), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 41/130 (32%), Positives = 56/130 (43%), Gaps = 28/130 (22%)
Query 48 DLPTNITVLNLTHNQLRRLPA---------ANFTRYSQLTS-------LDVGFNTISKLE 91
DLP ++ LN+ NQL LPA A+F ++L LD N IS
Sbjct 257 DLPPSLVDLNVRKNQLIELPALPPDLERLIASFNHLAELPELPPNLSYLDASRNEISS-- 314
Query 92 PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
LC P L LN++ N+L +L A +L L N + ++ P NL
Sbjct 315 --LCDLPPSLVDLNVRKNQLIELP----ALPPDLERLIASFNHLAELPELP----PNLSY 364
Query 152 LDLSHNGLSS 161
LD S N +SS
Sbjct 365 LDASRNEISS 374
Score = 34.3 bits (77), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 40/130 (31%), Positives = 56/130 (43%), Gaps = 28/130 (22%)
Query 48 DLPTNITVLNLTHNQLRRLPA---------ANFTRYSQLTS-------LDVGFNTISKLE 91
DLP ++ L++ NQL LPA A+F ++L LD N IS
Sbjct 197 DLPPSLVYLDVRDNQLIELPALPSGLERLIASFNHLAELPELPPNLYYLDASRNEISS-- 254
Query 92 PELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLIT 151
LC P L LN++ N+L +L A +L L N + ++ P NL
Sbjct 255 --LCDLPPSLVDLNVRKNQLIELP----ALPPDLERLIASFNHLAELPELP----PNLSY 304
Query 152 LDLSHNGLSS 161
LD S N +SS
Sbjct 305 LDASRNEISS 314
>3rgx_A A Protein BRASSINOSTEROID INSENSITIVE 1
Length=768
Score = 35.0 bits (79), Expect = 4.2, Method: Compositional matrix adjust.
Identities = 28/105 (27%), Positives = 42/105 (40%), Gaps = 0/105 (0%)
Query 57 NLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSD 116
N+T + F + LD+ +N +S P+ +P L +LNL HN++S
Sbjct 614 NITSRVYXXXXSPTFDNNGSMMFLDMSYNMLSGYIPKEIGSMPYLFILNLGHNDISGSIP 673
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L L L SN + L +DLS+N LS
Sbjct 674 DEVGDLRGLNILDLSSNKLDGRIPQAMSALTMLTEIDLSNNNLSG 718
>4eo7_A A Myeloid differentiation primary response protein MyD88
Length=148
Score = 33.5 bits (75), Expect = 4.9, Method: Composition-based stats.
Identities = 21/78 (27%), Positives = 41/78 (53%), Gaps = 5/78 (6%)
Query 752 EQFEYAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSI--KR 809
E+F+ A+I + D +V E +E+ + LK C+ +RD G + +I + + KR
Sbjct 7 ERFD--AFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTC-VWSIASELIEKR 63
Query 810 SRKIIFVITHHLLKDPLC 827
R+++ V++ L+ C
Sbjct 64 CRRMVVVVSDDYLQSKEC 81
>7l6w_A A Myeloid differentiation primary response protein MyD88
Length=138
Score = 33.1 bits (74), Expect = 5.7, Method: Composition-based stats.
Identities = 21/78 (27%), Positives = 41/78 (53%), Gaps = 5/78 (6%)
Query 752 EQFEYAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSI--KR 809
E+F+ A+I + D +V E +E+ + LK C+ +RD G + +I + + KR
Sbjct 1 ERFD--AFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTC-VWSIASELIEKR 57
Query 810 SRKIIFVITHHLLKDPLC 827
R+++ V++ L+ C
Sbjct 58 CRRMVVVVSDDYLQSKEC 75
>4lsx_A A Protein BRASSINOSTEROID INSENSITIVE 1
Length=774
Score = 34.7 bits (78), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 28/105 (27%), Positives = 42/105 (40%), Gaps = 0/105 (0%)
Query 57 NLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSD 116
N+T + F + LD+ +N +S P+ +P L +LNL HN++S
Sbjct 613 NITSRVYEGHTSPTFDNNGSMMFLDMSYNMLSGYIPKEIGSMPYLFILNLGHNDISGSIP 672
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L L L SN + L +DLS+N LS
Sbjct 673 DEVGDLRGLNILDLSSNKLDGRIPQAMSALTMLTEIDLSNNNLSG 717
>4lsx_B B Protein BRASSINOSTEROID INSENSITIVE 1
Length=774
Score = 34.7 bits (78), Expect = 5.7, Method: Compositional matrix adjust.
Identities = 28/105 (27%), Positives = 42/105 (40%), Gaps = 0/105 (0%)
Query 57 NLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSD 116
N+T + F + LD+ +N +S P+ +P L +LNL HN++S
Sbjct 613 NITSRVYEGHTSPTFDNNGSMMFLDMSYNMLSGYIPKEIGSMPYLFILNLGHNDISGSIP 672
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L L L SN + L +DLS+N LS
Sbjct 673 DEVGDLRGLNILDLSSNKLDGRIPQAMSALTMLTEIDLSNNNLSG 717
>6g2i_D F Acetyl-CoA carboxylase 1
Length=2350
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1055 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1114
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKEF 212
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1115 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1171
>6g2i_F A Acetyl-CoA carboxylase 1
Length=2350
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1055 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1114
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKEF 212
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1115 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1171
>6g2i_E B Acetyl-CoA carboxylase 1
Length=2350
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1055 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1114
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKEF 212
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1115 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1171
>6g2i_A D Acetyl-CoA carboxylase 1
Length=2350
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1055 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1114
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKEF 212
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1115 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1171
>6g2i_C C Acetyl-CoA carboxylase 1
Length=2350
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1055 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1114
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKEF 212
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1115 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1171
>6g2i_B E Acetyl-CoA carboxylase 1
Length=2350
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1055 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1114
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKEF 212
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1115 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1171
>4lsa_A A Protein BRASSINOSTEROID INSENSITIVE 1
Length=774
Score = 34.7 bits (78), Expect = 5.9, Method: Compositional matrix adjust.
Identities = 28/105 (27%), Positives = 42/105 (40%), Gaps = 0/105 (0%)
Query 57 NLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSD 116
N+T + F + LD+ +N +S P+ +P L +LNL HN++S
Sbjct 613 NITSRVYEGHTSPTFDNNGSMMFLDMSYNMLSGYIPKEIGSMPYLFILNLGHNDISGSIP 672
Query 117 KTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L L L SN + L +DLS+N LS
Sbjct 673 DEVGDLRGLNILDLSSNKLDGRIPQAMSALTMLTEIDLSNNNLSG 717
>6g2i_J R Acetyl-CoA carboxylase 1
Length=2350
Score = 34.7 bits (78), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1055 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1114
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKEF 212
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1115 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1171
>6g2i_I J Acetyl-CoA carboxylase 1
Length=2350
Score = 34.7 bits (78), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1055 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1114
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKEF 212
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1115 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1171
>6g2h_A D Acetyl-CoA carboxylase 1
Length=2407
Score = 34.7 bits (78), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1116 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1175
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKEF 212
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1176 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1232
>6g2h_B E Acetyl-CoA carboxylase 1
Length=2407
Score = 34.7 bits (78), Expect = 6.3, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1116 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1175
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKEF 212
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1176 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1232
>3riz_A A Protein BRASSINOSTEROID INSENSITIVE 1
Length=772
Score = 34.7 bits (78), Expect = 6.4, Method: Compositional matrix adjust.
Identities = 26/94 (28%), Positives = 39/94 (41%), Gaps = 0/94 (0%)
Query 68 AANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTE 127
+ F + LD+ +N +S P+ +P L +LNL HN++S L
Sbjct 622 SPTFDNNGSMMFLDMSYNMLSGYIPKEIGSMPYLFILNLGHNDISGSIPDEVGDLRGLNI 681
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L L SN + L +DLS+N LS
Sbjct 682 LDLSSNKLDGRIPQAMSALTMLTEIDLSNNNLSG 715
>4m7e_A A Protein BRASSINOSTEROID INSENSITIVE 1
Length=767
Score = 34.7 bits (78), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 26/94 (28%), Positives = 39/94 (41%), Gaps = 0/94 (0%)
Query 68 AANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTE 127
+ F + LD+ +N +S P+ +P L +LNL HN++S L
Sbjct 624 SPTFDNNGSMMFLDMSYNMLSGYIPKEIGSMPYLFILNLGHNDISGSIPDEVGDLRGLNI 683
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L L SN + L +DLS+N LS
Sbjct 684 LDLSSNKLDGRIPQAMSALTMLTEIDLSNNNLSG 717
>4m7e_B B Protein BRASSINOSTEROID INSENSITIVE 1
Length=767
Score = 34.7 bits (78), Expect = 6.5, Method: Compositional matrix adjust.
Identities = 26/94 (28%), Positives = 39/94 (41%), Gaps = 0/94 (0%)
Query 68 AANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTE 127
+ F + LD+ +N +S P+ +P L +LNL HN++S L
Sbjct 624 SPTFDNNGSMMFLDMSYNMLSGYIPKEIGSMPYLFILNLGHNDISGSIPDEVGDLRGLNI 683
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L L SN + L +DLS+N LS
Sbjct 684 LDLSSNKLDGRIPQAMSALTMLTEIDLSNNNLSG 717
>6g2d_C D Acetyl-CoA carboxylase 1
Length=2407
Score = 34.7 bits (78), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1116 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1175
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKEF 212
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1176 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1232
>6g2d_B C Acetyl-CoA carboxylase 1
Length=2407
Score = 34.7 bits (78), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 29/117 (25%), Positives = 53/117 (45%), Gaps = 18/117 (15%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1116 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1175
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKEF 212
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1176 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQL 1232
>3rj0_A A Protein BRASSINOSTEROID INSENSITIVE 1
Length=772
Score = 34.7 bits (78), Expect = 6.6, Method: Compositional matrix adjust.
Identities = 26/94 (28%), Positives = 39/94 (41%), Gaps = 0/94 (0%)
Query 68 AANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTE 127
+ F + LD+ +N +S P+ +P L +LNL HN++S L
Sbjct 622 SPTFDNNGSMMFLDMSYNMLSGYIPKEIGSMPYLFILNLGHNDISGSIPDEVGDLRGLNI 681
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L L SN + L +DLS+N LS
Sbjct 682 LDLSSNKLDGRIPQAMSALTMLTEIDLSNNNLSG 715
>7beq_A A Myeloid differentiation primary response protein MyD88
Length=151
Score = 33.1 bits (74), Expect = 6.7, Method: Composition-based stats.
Identities = 21/78 (27%), Positives = 41/78 (53%), Gaps = 5/78 (6%)
Query 752 EQFEYAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSI--KR 809
E+F+ A+I + D +V E +E+ + LK C+ +RD G + +I + + KR
Sbjct 6 ERFD--AFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTC-VWSIASELIEKR 62
Query 810 SRKIIFVITHHLLKDPLC 827
R+++ V++ L+ C
Sbjct 63 CRRMVVVVSDDYLQSKEC 80
>7ber_A A Myeloid differentiation primary response protein MyD88
Length=151
Score = 33.1 bits (74), Expect = 6.7, Method: Composition-based stats.
Identities = 21/78 (27%), Positives = 41/78 (53%), Gaps = 5/78 (6%)
Query 752 EQFEYAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSI--KR 809
E+F+ A+I + D +V E +E+ + LK C+ +RD G + +I + + KR
Sbjct 6 ERFD--AFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTC-VWSIASELIEKR 62
Query 810 SRKIIFVITHHLLKDPLC 827
R+++ V++ L+ C
Sbjct 63 CRRMVVVVSDDYLQSKEC 80
>6fif_A A Protein BRASSINOSTEROID INSENSITIVE 1
Length=837
Score = 34.7 bits (78), Expect = 6.7, Method: Compositional matrix adjust.
Identities = 26/94 (28%), Positives = 39/94 (41%), Gaps = 0/94 (0%)
Query 68 AANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTE 127
+ F + LD+ +N +S P+ +P L +LNL HN++S L
Sbjct 647 SPTFDNNGSMMFLDMSYNMLSGYIPKEIGSMPYLFILNLGHNDISGSIPDEVGDLRGLNI 706
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L L SN + L +DLS+N LS
Sbjct 707 LDLSSNKLDGRIPQAMSALTMLTEIDLSNNNLSG 740
>2z5v_A A Myeloid differentiation primary response protein MyD88
Length=149
Score = 33.1 bits (74), Expect = 6.8, Method: Composition-based stats.
Identities = 21/78 (27%), Positives = 41/78 (53%), Gaps = 5/78 (6%)
Query 752 EQFEYAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSI--KR 809
E+F+ A+I + D +V E +E+ + LK C+ +RD G + +I + + KR
Sbjct 12 ERFD--AFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTC-VWSIASELIEKR 68
Query 810 SRKIIFVITHHLLKDPLC 827
R+++ V++ L+ C
Sbjct 69 CRRMVVVVSDDYLQSKEC 86
>3rgz_A A Protein BRASSINOSTEROID INSENSITIVE 1
Length=768
Score = 34.3 bits (77), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 26/94 (28%), Positives = 39/94 (41%), Gaps = 0/94 (0%)
Query 68 AANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNELSQLSDKTFAFCTNLTE 127
+ F + LD+ +N +S P+ +P L +LNL HN++S L
Sbjct 625 SPTFDNNGSMMFLDMSYNMLSGYIPKEIGSMPYLFILNLGHNDISGSIPDEVGDLRGLNI 684
Query 128 LHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSS 161
L L SN + L +DLS+N LS
Sbjct 685 LDLSSNKLDGRIPQAMSALTMLTEIDLSNNNLSG 718
>4eco_A A Uncharacterized protein
Length=692
Score = 34.3 bits (77), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 8/100 (8%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL-------EPELCQKLPMLKVL 104
N++ +NL++NQ+ + P F+ S L+S+++ N ++++ E E + +L +
Sbjct 434 NVSSINLSNNQISKFPKELFSTGSPLSSINLMGNMLTEIPKNSLKDENENFKNTYLLTSI 493
Query 105 NLQHNELSQLSDKTFAFC-TNLTELHLMSNSIQKIKNNPF 143
+L+ N+L++LSD A L + L NS K P
Sbjct 494 DLRFNKLTKLSDDFRATTLPYLVGIDLSYNSFSKFPTQPL 533
>2js7_A A Myeloid differentiation primary response protein MyD88
Length=160
Score = 33.1 bits (74), Expect = 7.2, Method: Composition-based stats.
Identities = 21/78 (27%), Positives = 41/78 (53%), Gaps = 5/78 (6%)
Query 752 EQFEYAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSI--KR 809
E+F+ A+I + D +V E +E+ + LK C+ +RD G + +I + + KR
Sbjct 15 ERFD--AFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTC-VWSIASELIEKR 71
Query 810 SRKIIFVITHHLLKDPLC 827
R+++ V++ L+ C
Sbjct 72 CRRMVVVVSDDYLQSKEC 89
>4eco_B B Uncharacterized protein
Length=692
Score = 34.3 bits (77), Expect = 7.4, Method: Compositional matrix adjust.
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 8/100 (8%)
Query 52 NITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKL-------EPELCQKLPMLKVL 104
N++ +NL++NQ+ + P F+ S L+S+++ N ++++ E E + +L +
Sbjct 434 NVSSINLSNNQISKFPKELFSTGSPLSSINLMGNMLTEIPKNSLKDENENFKNTYLLTSI 493
Query 105 NLQHNELSQLSDKTFAFC-TNLTELHLMSNSIQKIKNNPF 143
+L+ N+L++LSD A L + L NS K P
Sbjct 494 DLRFNKLTKLSDDFRATTLPYLVGIDLSYNSFSKFPTQPL 533
>6g2d_A B Acetyl-CoA carboxylase 1
Length=2407
Score = 34.3 bits (77), Expect = 7.8, Method: Compositional matrix adjust.
Identities = 29/116 (25%), Positives = 53/116 (46%), Gaps = 18/116 (16%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1116 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1175
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKE 211
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1176 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQ 1231
>6g2h_E B Acetyl-CoA carboxylase 1
Length=2407
Score = 34.3 bits (77), Expect = 7.9, Method: Compositional matrix adjust.
Identities = 29/116 (25%), Positives = 53/116 (46%), Gaps = 18/116 (16%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1116 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1175
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKE 211
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1176 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQ 1231
>6g2h_F A Acetyl-CoA carboxylase 1
Length=2407
Score = 34.3 bits (77), Expect = 7.9, Method: Compositional matrix adjust.
Identities = 29/116 (25%), Positives = 53/116 (46%), Gaps = 18/116 (16%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1116 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1175
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKE 211
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1176 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQ 1231
>6g2d_D F Acetyl-CoA carboxylase 1
Length=2407
Score = 34.3 bits (77), Expect = 9.2, Method: Compositional matrix adjust.
Identities = 29/116 (25%), Positives = 53/116 (46%), Gaps = 18/116 (16%)
Query 114 LSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKL------GTQ 167
L+D+ T LT+L +N+ ++ + +L + +L HN + S L G Q
Sbjct 1116 LTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQ 1175
Query 168 VQLENLQELLLSNNKI------------QALKSEELDIFANSSLKKLELSSNQIKE 211
+ENLQ+L+LS I Q ++ L+++ + EL+S Q ++
Sbjct 1176 FCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQ 1231
>1xeu_A A internalin C
Length=263
Score = 33.5 bits (75), Expect = 9.7, Method: Compositional matrix adjust.
Identities = 35/116 (30%), Positives = 54/116 (47%), Gaps = 23/116 (20%)
Query 445 QELTGQEWRGLENIFEIYLSYNKYLQLTRNSFALVPSLQRLMLRRVALKNVDSSPSP--- 501
Q L G ++ N+ E++LS+N+ L+ + L+ L + R LKN++ PS
Sbjct 54 QSLAGMQF--FTNLKELHLSHNQISDLS--PLKDLTKLEELSVNRNRLKNLNGIPSACLS 109
Query 502 --------------FQPLRNLTILDLSNNNIANINDDMLEGLEKLEILDLQHNNLA 543
L+NL IL + NN + +I ML L KLE+LDL N +
Sbjct 110 RLFLDNNELRDTDSLIHLKNLEILSIRNNKLKSI--VMLGFLSKLEVLDLHGNEIT 163
>4xa9_M G Gala protein type 1, 3 or 4
Length=297
Score = 33.5 bits (75), Expect = 9.9, Method: Compositional matrix adjust.
Identities = 53/205 (26%), Positives = 83/205 (40%), Gaps = 30/205 (15%)
Query 51 TNITVLNLTHNQLRRLPAANFTRYSQLTSLDVGFNTISKLEPELCQKLPMLKVLNLQHNE 110
T+++ LN++HN + A + + +T+LDV F NE
Sbjct 67 TSVSSLNISHNNIGPEGAQWLSEDNHITTLDVSF------------------------NE 102
Query 111 LSQLSDKTFAFCTNLTELHLMSNSIQKIKNNPFVKQKNLITLDLSHNGLSSTKLGTQVQL 170
+ K A L L+ + N I K+ ++ Q NL +DL N L +
Sbjct 103 IGDEGVKALAANAKLITLYALYNKITKV-GAGYLAQSNLKKIDLCFNSLEDEGVIALASN 161
Query 171 ENLQELLLSNNKIQALKSEELDIFANSSLKKLELSSNQIKEFSPGCFHAIGRLFGLFLNN 230
N++EL+ S + + + EL N+ L L L N I + S F L L L +
Sbjct 162 INIKELIASACDVSDIGAIEL--AKNNQLTLLILGKNAITDKSTLHFANNTSLSTLHLGS 219
Query 231 VQLGPSLTEKLCLELANTSIRNLSL 255
Q+ + K LE NT I +L L
Sbjct 220 NQI--TAAGKKILE-TNTRITDLDL 241
Lambda K H a alpha
0.322 0.137 0.410 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 104275768296
Database: unitmol_20240501.fasta
Posted date: May 2, 2024 10:24 AM
Number of letters in database: 240,313,072
Number of sequences in database: 835,512
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40