#WARNING:no index is registered index "YP_009725301.1" in "https://rest.uniprot.org/uniprotkb/" url "https://rest.uniprot.org/uniprotkb/YP_009725301.1.txt".
Please visit the UniProt website(https://www.uniprot.org), and get a proper ID/AC for your query protein. site aa pred_sec pred_expbur pred_accessibility pdb_asym_id hetero nucleotide compound metal otherpoly homo precipitant A C D E F G H I K L M N P Q R S T V W Y feature_table variant 1 S e 56.2 6xbi_A R1AB_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:Calpeptin[3 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:3C-like proteinase[5 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:Macrocyclic peptide inhibitor[15 aa] U0P:UGG:O4F:K36:B1S:V2M:O6K:P6N:RY5:S8T:SQ5:TU8:GQU:H6F:H6L:J7R:KOI:KW9:L1F:L6D:LBC:LBO:LWO:Y6J:R30:M0X:KU6:860:M7X:MU3:MZF:N3R:N43:N4L:N5L:N6X:NB0:NJU:NKU:NM0:NO0:NQO:NRX:O0X:O87:OCI:OIE:OIK:OIX:OK9:OKW:ONU:OQF:OQL:OQX:ORR:OVF:OVX:OWX:OZC:OZX:P0X:P6O:P9O:PKW:PQ6:PZ6:Q1U:Q2G:Q3U:Q45:QE3:QEX:QFU:QH6:QI4:QIB:QJ6:PUU:QJL:QKB:QKI:QNU:QOC:QQF:QC3:QUQ:QV9:QVG:QY6:R6L:RAQ:RBX:RG3:RG9:RHI:RJ3:RJF:RSL:RVL:RW0:RXU:S1U:S39:S3X:XWZ:Y2C:Y25:Y1R:VJA:GHX:VHJ:VHM:XM2:NOL:X7V:AG7:XTJ:XTM:XTP:Y6A:Y6G:YCV:YHJ:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:YD1:U7W:U9H:V18:V1B:UED:Z26:87H:I1W:Y48:4WI:U88:7XB:3XI:59S:5IW:IFO:XNV:V9R:MXU:M9X:MFL:MJ0:P6I:P6R:U2I:7YY:U76:X6T:Y0I:Y0E:Y8O:VQN:XH9:XHW:XJ9:ZQB:WOK NA:NI R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[307 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[300 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:EDO:ACT:PEG:PGE 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 0 0 DISORDER:predicted by DISOPRED 2 G e 78.6 6xbi_A T5D R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[307 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[300 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] EDO:DMS:IPA:FMT:GOL 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DISORDER:predicted by DISOPRED 3 F b 10.5 6xbi_A T5D R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:3C-like proteinase[303 aa]:3C-like proteinase[300 aa]:3C-like proteinase[296 aa]:3C-like proteinase[299 aa]:3C-like proteinase[297 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-Like Protease[306 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1ab[306 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase nsp5[300 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] GOL:DMS:PEG:IPA:FMT:EDO:PO4:1PE 0 0 0 0 26 0 0 16 0 58 0 0 0 0 0 0 0 0 0 0 DISORDER:predicted by DISOPRED 4 R e 78.3 6xbi_A T5D:U1V:XY4 CL:NA R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] GOL:EDO:PEG:DMS:SO4:PO4:MLI:1PE:FMT 0 0 0 0 0 0 0 0 21 0 0 0 0 0 39 0 8 32 0 0 DISORDER:predicted by DISOPRED 5 K e 39.6 6xbi_A U1V:XY4 CL R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] GOL:EDO:PEG:DMS:SO4:PO4:MLI:1PE:FMT 0 0 0 0 0 0 0 0 92 0 0 0 0 0 8 0 0 0 0 0 DISORDER:predicted by DISOPRED 6 M e 41.1 6xbi_A JGY:U1V:XZI:XZE CL R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:EDO:IMD:1PE:GOL:FMT 0 0 0 0 0 0 0 0 0 15 85 0 0 0 0 0 0 0 0 0 DISORDER:predicted by DISOPRED 7 A e 24.1 6xbi_A JGY:XZI:XZE:XY4 R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:EDO:IMD:PEG:1PE:GOL:FMT 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 31 0 0 8 F b 1.4 6xbi_A JGY:U1V:XZI:XZE CL R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:IMD:EDO:GOL:1PE:FMT 10 0 0 0 16 0 13 0 0 0 0 6 0 35 0 20 0 0 0 0 DISORDER:predicted by DISOPRED 9 P e 62.0 6xbi_A CL R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] GOL 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 10 S b 15.6 6xbi_A CL R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84 16 0 0 0 11 G H e 58.3 6xbi_A YQN CL R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] EDO:DMS 0 0 0 0 0 69 0 0 0 0 0 0 0 0 0 31 0 0 0 0 12 K H e 23.1 6xbi_A S7D:U0S:YQN CL R1AB_SARS2:R1A_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[300 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase nsp5[306 aa] EDO:DMS:GOL 20 6 5 0 6 0 0 6 27 13 0 0 0 0 0 0 0 16 0 0 13 V H b 0.0 6xbi_A 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 95 0 0 14 E H e 43.7 6xbi_A YQN CL:NA R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:GOL:PG4:EDO:PEG:SO4:1PE:FMT 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 G T e 23.8 6xbi_A YQN CL R1AB_SARS2:3C-like proteinase[310 aa] DMS:GOL:ACT:PG4:EDO:PEG:SO4:1PE:FMT 5 0 0 0 0 17 0 0 27 0 0 10 35 0 6 0 0 0 0 0 16 C T b 0.0 6xbi_A DMS:GOL:EDO:SO4:FMT 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 M E b 5.8 6xbi_A YQN CA:NA:CL R1AB_SARS2:3C-like proteinase[310 aa] DMS:GOL:ACT:PG4:EDO:PEG:SO4:FMT:1PE 0 0 0 0 0 0 0 43 0 13 21 0 0 0 0 0 0 23 0 0 18 V E b 0.7 6xbi_A NA DMS:GOL:ACT:EDO:SO4:FMT 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 19 Q E b 19.4 6xbi_A R1AB_SARS2:nsp4/5 peptidyl substrate[10 aa]:Nonstructural protein 4/5[12 aa] R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] DMS:EDO:FMT:PEG:GOL:PO4 0 0 0 0 0 0 0 0 8 0 0 0 0 26 35 31 0 0 0 0 20 V E b 0.0 6xbi_A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 21 T E b 19.5 6xbi_A R1AB_SARS2:nsp4/5 peptidyl substrate[10 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 10/11[10 aa] DMS:PEG:EDO 5 18 0 0 0 0 0 0 0 0 0 8 0 0 0 26 42 0 0 0 22 C E b 3.3 6xbi_A DMS:PEG:FMT:EDO 0 26 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 74 23 G T e 76.2 6xbi_A R1A_SARS2:Nonstructural protein 4/5[12 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 10/11[10 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa] PEG:DMS:FMT:EDO 0 0 0 0 0 85 0 0 0 0 0 0 0 0 15 0 0 0 0 0 24 T T e 90.9 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 15/16[9 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa] T1Y:T4J:T6Y:T7A:T9M:T9P:U1M:O3U:O4L:G65:XNJ:Y6J:YSP:YVY:FN7:7XB:7YY:ILE:V3E:VQN R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] DMS:PEG:FMT:EDO 0 0 0 0 0 15 0 0 0 0 0 39 0 0 0 35 11 0 0 0 25 T E e 31.2 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW248[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa] T1Y:T2J:T2V:T4D:T4J:NTG:T6M:T6V:T71:T7A:T7J:T7P:T81:T8A:T8D:T8J:T8S:T8Y:T9M:T9P:U0M:U0P:U1A:U1M:US7:UPJ:X77:NNA:V7G:Q5T:R8H:RV5:S8T:MYC:PK8:SV6:H3F:HER:HUR:HUO:KLR:KP0:KQ3:KSI:L2I:L8O:LKI:LQU:LWO:Y6J:R30:M0X:LZX:MVR:O3U:O4L:O5C:OD7:OEO:OFX:OGF:OQF:OQX:OUF:OV4:OVF:OYX:Q5C:Q60:Q6U:Q7R:Q8O:QBR:QD9:QJL:QK3:QLC:QMX:QQU:QR9:QSX:QU9:QVJ:QXI:R2X:ZHA:Y0W:NT9:G65:TG3:X7V:0EN:XEY:XF1:XF4:XF7:XFD:XNJ:AG7:Y6A:Y6G:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:FN7:ZL7:7IL:90I:90X:4W8:8H9:I1W:I2D:I2N:M0C:O5F:O5O:5IL:7XB:G7O:XNV:M9X:QH0:P5X:P6I:P6R:U1J:T2L:T43:7YY:U6Y:X6O:X70:X6T:X9Z:XA8:K9U:06Q:0BO:LVX:LKR:OF9:ILE:V3E:VQR:I3R:A1W:WZK:JJC:JJO:JKL:WOK:WTE:WTV:A1ADS R1AB_SARS2:3C-like proteinase[11 aa] DMS:HVB:EDO:IMD:GLY:ETF:FMT:GOL:PEG:PO4:ALA 0 0 0 0 0 0 0 0 0 6 45 26 0 0 0 0 23 0 0 0 26 T E e 29.2 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW246[4 aa]:inhibitor UAW248[5 aa]:UAW243[4 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa] T1V:T1Y:T2J:T2V:T2Y:T3G:T3V:T4J:T6M:T6V:T7A:T7J:T7P:T7Y:T8D:T8V:T8Y:T9M:T9P:U0P:U1A:U1M:X77:U5G:NEN:SV6:NNA:O6K:Q5T:R8H:MYC:PK8:HER:KSI:LRN:LW6:LZX:O3U:O4L:O5C:Q60:QBR:QLC:QQU:QVJ:TG3:X7V:0EN:XEY:XF1:XF4:XF7:XFD:AG7:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:FN7:ZL7:7IL:90I:90X:8GW:I71:8H9:M0C:O5F:O5O:O69:5IL:7XB:XNV:M9X:MFL:MIJ:MJ0:QQL:U1J:7YY:U6Y:U76:X6O:X70:X9Z:XA8:0AX:0BO:LVX:LKR:OF9:ILE:VQR:I3R:A1W:WTE:WTV:A1ADS:X83:X8F:XKQ R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] DMS:PEG:EDO:ALA 6 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 56 23 0 0 27 L E b 2.8 6xbi_A NEMO_HUMAN:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa] T4J:T4M:T6V:T8V:T8Y:T9M:T9P:U0Y:U1A:U1G:U1M:USD:USA:U5G:UED:B1S:V2M:SV6:Q5T:MYC:PK8:H3F:HER:HUR:LZX:M5X:MWN:MX9:MZF:N2X:Q4F:Q6U:QQU:0TI:XXN:V7G:TG3:X7V:0EN:AG7:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:ZL7:35J:90I:I70:4IJ:4I9:I1W:O5F:O5O:XNV:V9R:QQL:QH0:T4V:SRU:7YY:Y0I:06Q:LKR:VQR:JJC:JKL:WTE:WTV:A1ADS CL:ZN DMS:PO4:ALA 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 28 N E b 0.0 6xbi_A 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 29 G E b 0.0 6xbi_A 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30 L E b 0.0 6xbi_A 0 0 0 0 0 0 0 8 0 86 0 0 0 0 0 0 0 6 0 0 31 W E b 9.2 6xbi_A T0S:YQN CL DMS:GOL:PG4:PEG:EDO:SO4:1PE:FMT:ACT 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 32 L E b 0.6 6xbi_A 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 33 D T e 46.9 6xbi_A T0V:T5Y:T6J:CLU:NT9 FMT:GOL 0 0 50 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 D T e 38.3 6xbi_A T6J:CLU 0 0 77 0 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 35 V E b 20.0 6xbi_A DMS:MLI:EDO 0 0 0 11 8 0 0 12 16 0 0 0 0 0 0 8 35 5 0 5 36 V E b 0.0 6xbi_A 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 85 0 0 37 Y E b 10.9 6xbi_A DMS:IMD:EDO:PEG 0 0 0 0 0 0 0 25 0 0 6 0 0 0 0 0 6 0 16 48 38 C E b 0.0 6xbi_A 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 39 P E b 0.0 6xbi_A XC4:AG7:4IJ:4I9:9FF CL:ZN:NA 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 40 R G b 17.4 6xbi_A BTB:0TI:XXN CL:NA DMS:FMT:PEG:EDO:GOL:TRS:PO4:1PE 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 41 H G b 18.8 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:Leupeptin[4 aa]:UAW243[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Calpain I Inhibitor[4 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] JFM:HWH:RZG:RZJ:RZS:K0G:GWS:LPZ:T0Y:T1V:T1Y:T2G:T2J:T2V:T2Y:T3G:T3J:T3V:T47:T4D:T4J:T4M:T4V:T4Y:T54:NTG:T67:JGG:T6M:T6V:T6Y:T71:T7A:T7D:T7G:T7J:T7P:T7S:T7V:T7Y:T81:T84:T8A:T8D:T8J:T8M:T8P:T8S:T8V:T8Y:T9J:U0M:U0Y:U1D:U1A:U1G:U1M:UHS:UGM:UGP:UH1:UH7:UHA:UHV:UHY:UJ1:UHM:UJ4:USD:USA:US7:UPD:VEG:VEJ:VEM:VEP:VEV:VEY:O46:FHR:FJC:3WL:X77:U5G:K36:UED:B1S:NEN:V2M:QYS:SV6:NNA:V7G:O6K:Q5T:FUA:R8H:SIN:RNW:RV5:RY5:S1W:S8T:SQ2:SQ5:MYC:SYH:T0W:PK8:ALD:TU8:JRY:GQU:H3F:EOF:H60:H63:H6F:H6L:H6R:HER:HUR:HUO:HYR:J7R:J7O:2XI:2RI:KFU:KG9:KJI:KJO:KL6:KLR:KMF:KMX:KNU:KO9:KOI:KP0:KQ3:KQL:KQX:KSI:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L2I:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L8F:L8O:L93:L9F:L9O:LB0:LBC:LBO:LCU:LDX:LKX:LKI:LJO:LJ0:LF3:LR0:LQU:LQ0:LO0:LM0:LRC:LRN:LS0:LSF:LT9:LUC:LV9:LVM:LW6:LWO:M4L:M2X:M26:Y6J:R30:M0X:M0G:LZX:MF0:M9U:M93:860:M7X:M6U:M6I:M5X:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:MWN:MX9:MZF:N0F:N0O:N0X:N1U:N2X:N3I:N3R:N43:N4L:N5L:N6X:N7L:N8X:N9I:NB0:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NQO:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:NZK:O0C:O0R:O0X:O1I:O1X:O2R:O3I:O3U:O4L:O5C:Z26:O87:O8L:O9O:O9X:OAO:OBO:OCI:OD7:ODX:OE6:OEO:OFX:OGF:OHC:OI4:OIE:OIK:OIX:OJ9:OJO:OK9:OKW:OLX:ONU:OGV:OGO:OO6:OOL:OPU:OQF:OQL:OQX:ORR:OSI:OT6:OUF:OV4:OVF:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PVR:PWR:PZ6:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4F:Q4R:Q5C:Q5K:Q5R:Q60:Q69:Q6U:Q7C:Q7R:Q8O:Q99:QBR:QC3:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QFU:QG3:QGC:QGO:QGX:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QX9:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZ0:QZC:QZL:QZU:R08:R0F:R0Q:R1I:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLH:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RR0:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:Y1L:Y1H:Y1C:ZHA:Y0W:Y3N:VXQ:NT9:Y0L:Y0H:Y0C:XZX:0TI:XXN:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:G65:X7V:XC4:0EN:XEY:XF1:XF4:XF7:XFD:XNJ:AG7:XTJ:XTM:XTP:XU4:XV4:XWS:Y6A:Y6G:YD1:YCV:YHJ:YHI:YMG:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:ZL7:U7W:U9H:UQW:UQZ:35J:USZ:V18:4N0:5P9:7IL:90I:90X:V1B:I70:4IT:4IJ:4I9:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZW:5ZT:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7YB:7YI:7YQ:7YZ:87H:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2D:I2N:NB2:V46:W48:I54:Q56:Y48:N63:S4L:ISG:U88:M0C:O5F:O5O:O69:5IL:ODN:7XB:3XI:40I:59S:5IZ:5IW:G7L:G7O:9FF:BOV:I8H:IFO:XNV:V9R:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:OZI:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U1J:U2B:SRU:T2L:T43:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LVX:LKR:OF9:VQR:VQN:83F:83N:84C:YQN:KKO:XI0:XH9:XHW:XJ9:I3R:A1W:WZK:ZQB:JVX:JJO:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 SE:ZN:CL:NA R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] DMS:HVB:EDO:IMD:GLY:ETF:FMT:PO4:ALA 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 42 V G b 0.0 6xbi_A NT9:I1W DMS:EDO 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 95 0 0 43 I G b 1.8 6xbi_A DMS:PEG:FMT:EDO 0 0 0 0 0 0 0 62 0 15 23 0 0 0 0 0 0 0 0 0 44 C b 6.7 6xbi_A R1AB_SARS2:nsp6/7 peptidyl substrate[10 aa]:Macrocyclic peptide inhibitor[15 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa] JFM:T0Y:T2J:T2V:T4D:NTG:T6Y:T71:T7A:T7J:T7P:T81:T8J:T8S:U0M:UJ4:US7:UPJ:VEJ:3WL:RNW:RV5:S1W:S8T:9JT:H3F:HER:HUO:HYR:J7O:2RI:KJI:KLR:KMF:KP0:KQ3:L2I:LKI:LQU:LRN:LWO:R30:M0X:MVR:N9I:NDI:NIJ:NW0:NZK:O3U:O4L:O87:OD7:OEO:OFX:OQF:OQX:OUF:OV4:OVF:OYX:PVR:Q4R:Q5C:Q6U:Q7R:Q8O:P3L:QD9:QJL:QK3:QMX:QQU:QSX:QU9:QXI:QZU:R0Q:R2X:ZHA:Y0W:VXQ:NT9:Y0L:Y0C:0TI:XXN:G65:X7V:XNJ:Y6A:Y6J:Y6G:YCV:ZL7:UQW:V1B:4W8:5YN:5YJ:5ZN:5ZJ:5ZB:5ZF:5ZT:I1W:I2D:I2N:O5F:O5O:O69:5IL:P5X:P6I:P6R:P7L:T2L:T43:Y0I:Y0E:06Q:V3E:A1W:WZK:JJC:JJO:WOK CL DMS:HVB:EDO:IMD:GLY:PEG:ETF 30 51 1 1 0 8 0 1 1 1 0 1 1 1 1 1 1 1 0 0 45 T e 49.4 6xbi_A R1AB_SARS2:nsp6/7 peptidyl substrate[10 aa]:Macrocyclic peptide inhibitor[15 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa] T0Y:T2J:T4D:T4M:NTG:T6Y:T71:T7A:T7P:T7S:T81:T8J:T8S:UPJ:RNW:RV5:S8T:9JT:H3F:HYR:KJI:KLR:KMF:KP0:KQ3:L2I:LKI:LWO:R30:M0X:MVR:NW0:NZK:O3U:O4L:OD7:OFX:OQX:OUF:OV4:OVF:OYX:PVR:Q4R:Q5C:Q7R:Q8O:QJL:QK3:QQU:QSX:QU9:QXI:R2X:Y0W:XXN:G65:Y6A:Y6J:Y6G:YCV:ZL7:I2D:I2N:O5F:5IL:P5X:P6I:P6R:P7L:06Q:V3E:A1W:JJC:JJO:WOK DMS:HVB:GLY:ETF:FMT:EDO:IMD 6 0 0 0 0 1 0 0 8 6 0 0 22 0 0 43 11 0 0 0 46 S T e 88.3 6xbi_A R1AB_SARS2:NEMO_HUMAN:UAW243[4 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 15/16[9 aa]:Macrocyclic peptide inhibitor[15 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa] JFM:T0Y:T2J:T4D:T4M:NTG:T71:T7A:T7D:T7G:T81:T8J:T8S:U0M:U1G:US7:UPD:UPJ:O4F:FUA:RNW:RV5:S1W:S8B:S8T:H3F:KJI:KLR:KMX:KP0:KQ3:LKI:LWO:R30:M0X:MX9:N2X:NZK:O3U:O4L:OAO:OD7:ODX:OEO:OFX:OQF:OQX:OT6:OUF:OV4:OVF:OYX:PVR:Q5C:Q6U:Q7R:Q8O:QGC:QI7:QMX:QR9:QSX:QU9:QXI:QYN:R2X:RD5:ZHA:Y0W:Y0H:G65:XNJ:Y6A:Y6J:Y6G:YCV:ZL7:R8H:I2D:I2N:O5F:5IL:V9R:P5X:P6I:P6R:P7L:V3E:A1W:JJC:JJO:WOK DMS:HVB:GLY:ETF:GOL 27 0 6 0 0 1 0 0 0 1 0 0 0 0 8 41 13 0 0 0 47 E T e 95.5 6xbi_A OUF EDO:PEG:DMS:GOL 5 0 29 11 0 15 0 0 0 0 0 0 0 0 0 11 29 0 0 0 48 D S e 37.0 6xbi_A KMF:MVR:XXN:Y0E NA DMS:GOL 0 0 29 8 0 0 0 0 8 0 0 12 0 16 0 17 11 0 0 0 49 M e 25.1 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:Leupeptin[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] JFM:HWH:RZG:RZJ:RZS:K0G:GWS:LPZ:T0Y:T2G:T2J:T2V:T3J:T47:T4D:T4M:T4V:T4Y:T54:T5G:NTG:T67:JGG:T6Y:T71:T7J:T7P:T7S:T81:T84:T8A:T8J:T8M:T8S:T9J:U0M:U0Y:U1D:U1G:UHS:UGD:UGG:UGM:UGP:UGS:UH4:UGV:UH7:UHA:UHV:UHY:UJ1:UHM:UJ4:US7:UPJ:VEG:VEJ:VEM:VEP:VEV:VEY:O46:FHR:FJC:3WL:X77:U5G:K36:UED:B1S:V2M:SV6:NNA:V7G:O6K:FUA:CB1:RNW:RV5:RV8:RY5:S1W:S8T:SQ2:SQ5:MYC:SYH:T0W:ALD:9JT:TU8:JRY:GQU:H3F:H60:H63:H6F:HER:HUR:HUO:HYR:J7R:J7O:2XI:2RI:KFU:KG9:KJI:KJO:KL6:KLR:KMF:KNU:KO9:KOI:KP0:KQ3:KQL:KQX:KSI:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L2I:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L8F:L8O:L93:L9O:LB0:LBC:LBO:LCU:LDX:LKX:LKI:LJO:LJ0:LF3:LR0:LQU:LQ0:LO0:LM0:LRC:LRN:LS0:LSF:LT9:LUC:LV9:LVM:LWO:M4L:M2X:M26:Y6J:R30:M0X:M0G:LZX:MF0:M9U:M93:860:M7X:M6U:M6I:M5X:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:MWN:MZF:N0F:N0O:N0X:N1U:N2X:N3I:N3R:N43:N4L:N5L:N6X:N7L:N8X:N9I:NB0:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NQO:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:NZK:O0C:O0R:O0X:O1I:O1X:O2R:O3I:O3U:O4L:O5C:Z26:O87:O8L:O9O:O9X:OAO:OBO:OCI:OD7:ODX:OE6:OEO:OFX:OGF:OHC:OI4:OIE:OIK:OIX:OJ9:OJO:OKW:OLX:ONU:OGV:OGO:OO6:OPU:OQF:OQL:OQX:ORR:OSI:OT6:OTV:OUF:OV4:OVF:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PVR:PWR:PZ6:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4F:Q4R:Q5C:Q5K:Q5R:Q60:Q69:Q6U:Q7C:Q7R:Q8O:Q99:QBR:QC3:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QFU:QG3:QGC:QGO:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QQF:QQO:QQU:QR9:QRS:QSF:QSX:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QX9:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZC:QZL:QZU:R08:R0F:R0Q:R1I:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RR0:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:Y1L:Y1H:Y1C:ZHA:Y0W:Y3N:VXQ:NT9:Y0L:Y0H:Y0C:XZX:0TI:XXN:VJA:GHX:VHV:VHJ:VHM:XM2:NOL:G65:TG3:X7V:0EN:XEY:XF1:XF4:XF7:XFD:XNJ:XTJ:XTP:XU4:XV4:XWS:Y6A:Y6G:YD1:YCV:YHJ:YHI:YMG:YSG:YSP:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:ZJ1:ZL7:U7W:U9H:UQW:UQZ:USZ:V18:4N0:5P9:7IL:90I:90X:V1B:4IT:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZW:5ZT:7V2:7VI:7VQ:7VW:7W5:81L:7Y2:7YB:7YI:7YQ:7YZ:87H:8G9:8GW:I71:I69:8I7:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2D:I2N:W48:N63:S4L:ISG:M0C:O5F:O5O:O69:5IL:ODN:40I:59S:5IZ:G7L:G7O:I8H:IFO:XNV:V9R:LQ6:LQL:MXU:M9X:MFL:MJ0:OW1:OZI:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U1J:U2B:U2I:SRU:SVL:T2L:T43:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LVX:LKR:OF9:V3E:VQR:VQN:83F:83W:YQN:KKO:XI0:XH9:XHW:XJ9:I3R:A1W:WZK:ZQB:JVX:JJC:JJO:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:I70:X83:X8F:XKQ:A1AD0 CL:NA R1AB_SARS2:3C-like proteinase[306 aa] DMS:EDO:IMD:GLY:ETF:FMT:GOL:PO4 6 0 0 0 8 0 0 0 0 23 27 0 0 7 5 0 11 12 0 0 50 L S e 68.5 6xbi_A R1AB_SARS2:ASN-ARG-ALA-THR-LEU-GLN[6 aa] HYR:OUF:JJO DMS:PEG 8 0 0 0 0 0 0 18 0 17 0 5 0 0 5 18 16 5 7 0 51 N S e 63.0 6xbi_A Q5T:XXN NA EDO:DMS:GOL 1 0 39 6 0 8 0 1 1 1 0 32 1 0 1 1 1 6 0 0 52 P b 6.2 6xbi_A BTB:HYR:NDI:NKU:0TI:YV7:YD1:5ZN CL:NA EDO:DMS:GOL:NO3:PO4 1 0 8 0 0 1 0 17 0 1 0 0 51 0 0 1 0 0 0 18 53 N e 49.1 6xbi_A BTB:XXN CL DMS:EDO:GOL:NO3:PO4 1 0 48 0 0 1 0 0 0 1 0 37 0 8 0 1 0 0 0 0 54 Y H b 7.4 6xbi_A R1AB_SARS2:inhibitor UAW247[3 aa]:Leupeptin[4 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Inhibitor 18 in bound form[4 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:3C-like proteinase[5 aa]:LEUPEPTIN[4 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:peptide 8-1[10 aa]:Mpro inhibitor[5 aa] RZG:T9J:UJ4:VEG:VEJ:VEM:VEV:VEY:FHR:3WL:U5G:UED:B1S:NNA:S1W:SQ2:SYH:T0W:K36:H63:H6F:H6L:BTB:HER:HYR:2RI:KMF:KQL:KT9:L7V:LBO:LCU:LDX:LJ0:LV9:LVM:Y6J:M6U:M5I:MVR:N9I:NB0:NDI:NIJ:NKU:NQ3:NW0:O87:O9O:OD7:OGF:OIK:OZC:Q1C:Q4R:Q5R:P3L:Y1H:Y1C:VXQ:Y0L:Y0C:0TI:XXN:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:X7V:XF1:XF4:XFD:XTJ:XTP:XU4:YD1:YHI:YSP:YTM:YVA:YV7:YVV:UQZ:5P9:V1B:I70:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZW:5ZT:7VQ:7YB:7YQ:7YZ:90U:91I:91Z:W48:S4L:ISG:M0C:3XI:40I:59S:G7L:IFO:LQ6:LQL:MJ0:OW1:OZI:PJR:QAO:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:K9U:0AX:0BO:KKO:XJ9:WOK CL DMS:EDO:GOL:NO3:PO4 1 0 0 0 0 1 12 0 0 1 0 0 0 0 0 1 0 0 8 73 55 E H e 63.3 6xbi_A O0S:BTB DMS:EDO:GOL:PO4 12 0 22 28 0 8 0 0 0 1 0 0 8 0 0 11 6 0 0 0 56 D H e 51.9 6xbi_A DMS:GOL 21 0 26 0 0 0 6 0 0 6 6 22 0 0 8 0 0 0 0 6 57 L H b 4.5 6xbi_A XXN GOL 6 0 0 11 0 0 0 0 0 50 0 0 0 0 0 18 0 15 0 0 58 L H b 9.0 6xbi_A T0J:O0S:NZD MG:NA 0 0 0 0 0 0 0 6 0 69 5 0 0 0 0 8 0 6 0 6 59 I H e 78.4 6xbi_A O0S NA DMS 0 16 0 0 0 0 0 21 0 6 14 15 0 0 0 17 0 11 0 0 60 R T e 65.2 6xbi_A GOL:DMS 0 0 0 0 0 0 0 0 0 15 0 0 0 0 53 26 6 0 0 0 61 K b 18.9 6xbi_A NA:NI PEG:DMS:GOL:FMT:EDO 23 0 0 0 0 0 0 0 21 18 11 0 0 0 0 0 0 27 0 0 62 S e 44.5 6xbi_A GOL:PEG:PO4 9 0 1 1 1 1 0 6 1 2 0 16 1 1 18 12 28 1 0 1 63 N G e 31.5 6xbi_A K3S:A82 NA GOL:DMS:PEG:PO4:1PE:EDO 1 0 1 1 1 1 0 1 1 24 0 50 1 1 1 12 1 1 0 1 64 H G e 80.1 6xbi_A NA:CA:NI DMS:GOL:PEG:IMD:FMT:PO4 0 0 0 0 0 5 71 0 0 5 0 0 0 0 0 11 0 0 0 8 65 N G e 30.9 6xbi_A CL DMS:PEG:IMD:FMT 0 0 24 15 0 0 0 0 0 0 0 40 0 0 0 21 0 0 0 0 66 F E b 3.3 6xbi_A 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 L E e 40.4 6xbi_A R1AB_SARS2:nsp4/5 peptidyl substrate[10 aa]:Nonstructural protein 4/5[12 aa] CL DMS:PEG:FMT 0 5 0 15 0 0 8 10 0 11 0 0 0 0 0 40 11 0 0 0 68 V E b 0.0 6xbi_A 0 0 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 71 0 0 69 Q E e 34.7 6xbi_A R1AB_SARS2:nsp4/5 peptidyl substrate[10 aa]:Nonstructural protein 4/5[12 aa] CL:NA DMS:EDO:FMT:PEG:GOL:PO4 5 0 0 0 0 0 0 6 0 6 11 0 0 26 0 31 7 8 0 0 70 A E b 17.9 6xbi_A T0S:YQN NA R1AB_SARS2:3C-like proteinase[310 aa]:3C-like proteinase nsp5[306 aa] DMS:GOL:ACT:PG4:EDO:PEG:SO4:FMT:1PE 11 0 0 0 6 16 6 0 11 0 0 0 0 8 0 28 15 0 0 0 71 G T e 83.3 6xbi_A T0S:YQN CL:NA R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase[310 aa]:3C-like proteinase[303 aa] DMS:EDO:SO4:FMT:GOL:PEG:ACT 16 0 6 0 0 39 0 0 0 0 0 25 0 15 0 0 0 0 0 0 72 N T e 97.6 6xbi_A YQN R1AB_SARS2:3C-like proteinase[306 aa] 0 0 0 0 0 14 7 0 0 0 0 41 10 5 16 0 6 0 0 0 73 V E e 52.7 6xbi_A T0S:YQN PG4:1PE:DMS:GOL 27 0 0 0 0 0 8 0 0 6 17 0 0 0 0 0 0 43 0 0 74 Q E e 64.3 6xbi_A DMS:GOL 0 0 0 0 35 0 0 0 0 0 0 23 0 11 0 16 15 0 0 0 75 L E b 2.2 6xbi_A DMS:PG4:1PE:GOL 0 0 0 0 0 0 0 8 0 92 0 0 0 0 0 0 0 0 0 0 76 R e 69.6 6xbi_A NA DMS:GOL:EDO 0 0 0 0 0 35 0 0 0 0 0 15 0 0 34 0 16 0 0 0 77 V E b 7.3 6xbi_A NA EDO 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 78 I E e 46.2 6xbi_A T0J:K1Y:NZD:A82 PEG:PG4:1PE:EDO 0 0 0 0 0 0 0 25 0 0 11 0 0 0 0 0 0 65 0 0 79 G E e 23.8 6xbi_A T0J:K3S:K1Y:NZD:UHG:A82:N00 DMS:PEG:PG4:1PE 5 0 0 0 0 41 0 0 0 0 0 0 0 0 0 54 0 0 0 0 80 H E e 32.5 6xbi_A T0J:O0S:K3S:K1Y:NZD:UHG:A82:N00 NA:NI EDO:DMS:PEG:FMT:PG4:MLI:1PE 29 0 0 0 0 0 34 0 0 0 0 0 0 0 15 0 0 6 0 16 81 S E e 44.5 6xbi_A O0S:K3S:K1Y:UHG:A82:N00 DMS:EDO:PEG:PG4:MLI:1PE 5 0 0 0 0 0 0 0 5 0 0 0 0 16 20 22 31 0 0 0 82 M E b 18.4 6xbi_A MG DMS:FMT 0 0 0 0 0 0 0 0 0 15 74 0 0 0 0 0 0 0 0 11 83 Q E e 30.1 6xbi_A R1AB_SARS2:3C-like proteinase[306 aa] GOL:EDO:DMS:FMT 0 0 0 8 0 0 12 0 26 0 0 0 0 26 17 0 0 10 0 0 84 N T e 44.8 6xbi_A CL R1AB_SARS2:3C-like proteinase[306 aa] DMS:FMT:PEG:EDO:GOL:1PE 0 0 0 0 0 89 0 0 0 0 0 11 0 0 0 0 0 0 0 0 85 C T b 10.0 6xbi_A CL:NA DMS:FMT:PEG:EDO 20 22 0 0 0 0 0 0 0 0 0 0 0 0 0 19 17 22 0 0 86 V E b 0.0 6xbi_A 0 0 0 0 0 0 0 0 0 46 6 11 0 5 0 0 6 26 0 0 87 L E b 0.0 6xbi_A 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 88 K E e 28.8 6xbi_A K1Y:UHG:A82:N00 DMS:EDO:PEG:PG4:MLI:1PE 0 0 0 0 0 0 6 15 35 0 0 0 0 6 11 0 0 27 0 0 89 L E b 0.0 6xbi_A 0 0 0 0 0 0 0 24 0 76 0 0 0 0 0 0 0 0 0 0 90 K E e 49.5 6xbi_A K1Y:NZD:UHG:A82:N00 DMS:EDO:PEG:PG4:MLI:1PE 0 0 0 0 0 0 0 0 45 0 0 0 0 15 0 0 40 0 0 0 91 V E b 0.7 6xbi_A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 85 0 0 92 D S e 53.1 6xbi_A GOL:PEG 15 0 29 5 0 0 0 0 0 0 0 23 0 0 0 18 11 0 0 0 93 T S e 41.6 6xbi_A T0S GOL:PEG 0 0 0 0 0 0 0 0 0 16 0 0 0 35 0 5 11 33 0 0 94 A e 54.5 6xbi_A T0V:T5Y:T6J:CLU PEG 36 0 0 0 0 0 0 0 0 0 0 14 0 16 0 18 6 11 0 0 95 N b 4.8 6xbi_A T0V:T5Y:T6J:CLU CL PG4:PEG:1PE:DMS:GOL 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 96 P T e 85.3 6xbi_A T0S:T0V:S7D:T6J:U0S:YQN CL IMD:DMS:FMT:PEG:GOL 15 0 0 0 0 0 0 0 0 0 6 0 55 0 0 6 0 18 0 0 97 K T e 70.3 6xbi_A T0S:T0V:S7D:U0S:YQN CL R1AB_SARS2:3C-like proteinase[310 aa]:3C-like proteinase nsp5[303 aa] DMS:GOL:IMD:EDO:PEG:SO4:1PE:FMT:PG4:ACT 0 0 0 15 0 0 18 0 19 0 0 22 0 5 6 10 0 0 0 5 98 T e 21.4 6xbi_A T0V:T5Y:S7D:U0S:CLU:NT9:LQZ IMD:DMS:FMT:GOL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 99 P b 16.3 6xbi_A S7D:U0S:NT9:LQZ DMS:FMT:GOL 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 100 K E e 70.8 6xbi_A S7D:NEN:S8H:9JT:HYR:NT9:LQZ CA:AU DMS:EDO:GOL:FMT 23 0 0 11 0 0 0 0 53 0 0 6 0 0 6 0 0 0 0 0 101 Y E e 29.6 6xbi_A NEN:S8H:9JT:HYR:NT9:U88:LQZ AU:CL DMS:IMD:EDO:GOL:FMT:PEG 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 0 0 0 0 77 102 K E e 55.7 6xbi_A NEN:S8H:9JT:HYR:U88:LQZ AU:ZN:CL R1AB_SARS2:3C-like proteinase[298 aa]:3C-like proteinase[305 aa] EDO:DMS:FMT:GOL:PEG 0 0 0 0 0 0 0 0 36 0 0 0 0 0 0 19 39 6 0 0 103 F E e 34.9 6xbi_A JJG:T1S:HV2:K1G:RQH CL R1AB_SARS2:3C-like proteinase[306 aa] GOL:DMS:IMD:EDO:FMT:PEG 0 0 0 0 88 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 104 V e 29.3 6xbi_A JJG:T1S:HV2:K1G:RQH R1AB_SARS2:3C-like proteinase[298 aa]:3C-like proteinase[306 aa] EDO:DMS 0 0 0 0 0 16 0 15 23 0 0 0 0 0 12 5 10 18 0 0 105 R e 43.1 6xbi_A JJG:LWA:T1S:HV2:K1G:RQH NA R1AB_SARS2:3C-like proteinase[306 aa] EDO:GOL:DMS:NO3 0 0 0 0 0 0 0 0 15 0 0 0 0 0 19 11 33 22 0 0 106 I b 8.2 6xbi_A LWA CL:BR R1AB_SARS2:3C-like proteinase[298 aa] DMS:EDO 15 0 0 0 0 0 0 16 0 18 0 0 0 0 0 0 0 51 0 0 107 Q e 66.8 6xbi_A LWA:LZE:QGO CL:BR R1AB_SARS2:3C-like proteinase[298 aa]:3C-like proteinase[306 aa]:3C-like proteinase[305 aa] DMS 0 0 0 0 0 0 0 0 56 0 0 15 0 11 11 8 0 0 0 0 108 P T e 35.7 6xbi_A LWA:LZE:QGO:GT7 R1AB_SARS2:3C-like proteinase[305 aa] DMS:GOL:PEG:EDO 5 15 0 0 0 0 0 0 0 0 0 0 66 0 0 6 8 0 0 0 109 G T b 9.5 6xbi_A LZE:QGO:GT7 GOL:EDO 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110 Q e 43.9 6xbi_A 6SU:LZE:QGO:GT7 CL:BR R1AB_SARS2:3C-like proteinase[298 aa] DMS:EDO 16 0 27 39 0 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 111 T E b 4.5 6xbi_A CL R1AB_SARS2:3C-like proteinase[298 aa] DMS 13 0 0 0 0 6 0 0 0 0 0 0 0 0 0 54 27 0 0 0 112 F E b 0.0 6xbi_A CL 0 0 0 0 92 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 113 S E b 0.0 6xbi_A 0 0 0 0 0 0 0 0 0 0 0 35 0 0 0 34 31 0 0 0 114 V E b 0.0 6xbi_A 0 0 0 0 0 0 0 50 0 8 0 0 0 0 0 0 0 42 0 0 115 L E b 1.7 6xbi_A NA R1AB_SARS2:R1A_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[306 aa]:3C-like proteinase[305 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[305 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[304 aa]:3C-Like Protease[306 aa]:3C-like proteinase nsp5[302 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Replicase polyprotein 1ab[302 aa] 15 0 0 0 0 0 0 0 0 85 0 0 0 0 0 0 0 0 0 0 116 A E b 4.5 6xbi_A R1AB_SARS2:R1A_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase[300 aa]:3C-like proteinase[299 aa]:3C-like proteinase[305 aa]:3C-like proteinase nsp5[306 aa]:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[283 aa]:3C-like proteinase nsp5[297 aa] DMS 85 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117 C E b 0.0 6xbi_A NA R1AB_SARS2:3C-like proteinase[306 aa] 24 69 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 118 Y E e 21.7 6xbi_A ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:Nonstructural protein 13/14[10 aa] JGY:93J:XZI:XZE R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[306 aa]:3C-like proteinase[305 aa]:3C-like proteinase[307 aa]:3C-like proteinase[303 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[300 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[302 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Replicase polyprotein 1ab[299 aa]:Non-structural protein 7[305 aa] DMS:EDO:GOL:IPA:1PE:PEG 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 119 N T e 55.8 6xbi_A Nonstructural protein 13/14[10 aa] T9P CL R1AB_SARS2:R1A_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[304 aa] DMS:EDO:GOL:PEG 0 0 26 17 0 15 0 0 0 0 0 42 0 0 0 0 0 0 0 0 120 G T b 14.3 6xbi_A CL:NA R1AB_SARS2:R1A_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[304 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase[305 aa] DMS:EDO:FMT:GOL 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121 S E e 57.0 6xbi_A R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[306 aa]:3C-like proteinase[305 aa]:3C-like proteinase[307 aa]:3C-like proteinase[303 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[300 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[302 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase nsp5[303 aa]:Replicase polyprotein 1ab[299 aa]:Non-structural protein 7[305 aa] DMS:EDO:GOL 6 17 0 0 0 0 0 6 16 8 0 0 0 0 16 17 15 0 0 0 122 P E e 38.8 6xbi_A CL:NA R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] EDO:GOL 24 0 0 0 0 0 0 0 0 0 0 0 56 0 0 5 0 15 0 0 123 S E e 63.3 6xbi_A JGY:U1V:XZI:XZE R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:IMD:EDO:GOL:1PE:FMT 12 0 0 0 0 11 0 8 0 0 0 0 0 22 0 17 23 7 0 0 124 G E e 38.1 6xbi_A R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:EDO:GOL 0 0 0 0 0 89 0 0 0 0 0 0 0 0 0 11 0 0 0 0 125 V E e 40.0 6xbi_A XY4 R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] EDO:DMS:PEG 16 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 5 64 0 0 126 Y E e 24.3 6xbi_A XY4 CL R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] EDO:PEG:DMS:1PE 0 0 0 0 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56 127 Q E b 8.7 6xbi_A JGY:U1V:XZI:XY4 CL R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:EDO:PEG:1PE:GOL 0 0 0 0 0 35 16 0 0 0 5 0 15 11 0 0 18 0 0 0 128 C E b 1.3 6xbi_A NA R1AB_SARS2:R1A_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[306 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[301 aa]:3C-like proteinase[298 aa]:3C-like proteinase[303 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1a[306 aa]:Replicase polyprotein 1ab[305 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1ab[306 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:3C-like proteinase nsp5[297 aa]:3C-like proteinase nsp5[295 aa]:Non-structural protein 7[305 aa] 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81 0 0 129 A E b 0.0 6xbi_A NA R1AB_SARS2:3C-like proteinase[306 aa] 11 0 0 0 0 0 0 0 0 0 0 45 0 0 0 0 39 5 0 0 130 M b 0.0 6xbi_A 0 0 0 0 0 0 0 0 0 19 81 0 0 0 0 0 0 0 0 0 131 R b 1.6 6xbi_A NA GOL:PEG:FMT 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 132 P T e 20.2 6xbi_A T1M:S7V:QGO:R9V CL R1AB_SARS2:3C-like proteinase[305 aa] DMS:GOL:MPD 0 0 0 0 0 0 5 0 0 0 0 0 16 5 0 55 18 0 0 0 133 N T b 12.7 6xbi_A T1M:R9V R1AB_SARS2:3C-like proteinase[305 aa] DMS:FMT:EDO:GOL:MPD 0 0 0 0 0 0 0 0 0 0 0 73 0 11 0 16 0 0 0 0 134 F S e 31.1 6xbi_A LWA NA R1AB_SARS2:3C-like proteinase[305 aa] EDO:GOL 0 0 0 0 11 34 0 0 0 0 0 0 0 0 0 10 0 0 6 39 135 T b 1.3 6xbi_A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 136 I B b 0.6 6xbi_A NA 0 0 0 0 0 0 0 92 0 0 8 0 0 0 0 0 0 0 0 0 137 K e 47.2 6xbi_A T5D NA R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:GOL:PEG:IPA:FMT 0 0 0 0 0 0 0 0 59 0 0 0 0 0 41 0 0 0 0 0 138 G e 23.8 6xbi_A T5D R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:GOL 23 0 0 0 0 77 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139 S e 64.8 6xbi_A R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] EDO 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 140 F b 2.9 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:UAW243[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Calpain I Inhibitor[4 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] K0G:GWS:SZY:AWP:T5V:T67:T9J:U0P:U0V:UHS:UGD:UGG:UGM:UGP:UH1:UH4:UGV:UH7:UHA:UHV:UHY:UJ1:UHM:UJ4:VEG:VEJ:VEM:VEP:VEV:VEY:O4F:FHR:FJC:X77:K36:UED:B1S:V2M:QYS:NNA:V7G:O6K:P6N:Q5T:R7Q:R8H:RV8:RY5:S8B:S8T:SQ2:SQ5:SYH:T0W:TU8:ALD:GQU:EOF:H60:H63:H6F:H6L:H6R:HUR:HUO:J7R:J7O:2XI:2RI:KFU:KG9:KJI:KJO:KLR:KO9:KOI:KP0:KQ3:KQL:KQX:KS0:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L2I:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L93:L9F:L9O:LB0:LBC:LBO:LCU:LDX:LKX:LJO:LJ0:LF3:LR0:LQ0:LO0:LRC:LS0:LSF:LT9:LUC:LV9:LVM:LWO:M4L:M2X:M26:Y6J:R30:M0X:M0G:LZX:MF0:M9U:M93:860:M7X:M6U:M6I:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:MZF:N0F:N0O:N0X:N1U:N2X:N3I:N3R:N43:N4L:N5L:N6X:N7L:N8X:N9I:NB0:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NQO:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:NZK:O0C:O0R:O0X:O1I:O1X:O2R:O3I:Z26:O87:O8L:O9O:O9X:OAO:OBO:OCI:OD7:ODX:OE6:OEO:OFX:OGF:OHC:OI4:OIE:OIK:OIX:OJ9:OK9:OKW:OLX:ONU:OGV:OGO:OO6:OPU:OQF:OQL:OQX:ORR:OSI:OT6:OTV:OV4:OVF:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PVR:PWR:PZ6:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4R:Q5C:Q5K:Q5R:Q60:Q7C:Q8O:Q99:QBR:QC3:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QFU:QG3:QGC:QGO:QGX:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QX9:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZ0:QZC:QZL:QZU:R08:R0F:R0Q:R1I:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLH:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RR0:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:XWH:XWZ:Y2C:Y25:Y1R:XZ6:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:G65:X7V:0EN:XEY:XF1:XF4:XF7:XFD:XNJ:AG7:XTJ:XTM:XTP:XU4:XV4:Y6A:Y6G:YD1:YCV:YHJ:YHI:YMG:YSG:YSP:YSJ:YTM:YU4:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:ASC:U7W:U9H:UQW:UQZ:35J:USZ:V18:4N0:5P9:7IL:90I:90X:V1B:I70:4IT:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZW:5ZT:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7Y2:7YB:7YI:7YQ:7YZ:87H:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2D:I2N:NB2:V46:W48:I54:Q56:Y48:N63:S4L:ISG:M0C:O5F:O5O:O69:7XB:3XI:40I:59S:5IZ:5IW:BOV:I8H:IFO:XNV:V9R:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U2B:U2I:T2L:T43:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LVX:OF9:VQR:VQN:83F:83N:84C:83W:YQN:KKO:XI0:XH9:XHW:XJ9:WZK:ZQB:JVX:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-like proteinase[11 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:EDO:FMT:IMD:GLY 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141 L e 69.1 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:UAW243[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Calpain I Inhibitor[4 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] K0G:GWS:SZY:AWP:T4V:T5V:T67:JGY:T6Y:T7Y:T81:T84:T9J:U0P:U0V:U1D:UHS:UGD:UGG:UGM:UGP:UH1:UH4:UGV:UH7:UHA:UHV:UHY:UJ1:UHM:UJ4:VEG:VEJ:VEM:VEP:VEV:VEY:O4F:FHR:FJC:3WL:X77:K36:UED:B1S:V2M:QYS:NNA:U5G:O6K:P6N:Q5T:R6Q:R7Q:R8H:RV8:RY5:S8B:93J:S8T:SQ2:SQ5:SYH:T0W:TU8:ALD:GQU:H3F:H60:H63:H6F:H6L:HUR:HUO:J7R:J7O:2XI:2RI:KFU:KG9:KJI:KJO:KLR:KO9:KOI:KP0:KQ3:KQL:KQX:KS0:KSI:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L2I:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L8O:L93:L9F:L9O:LB0:LBC:LBO:LCU:LDX:LKX:LJO:LJ0:LF3:LR0:LQ0:LO0:LRC:LS0:LSF:LT9:LUC:LV9:LVM:LWO:M4L:M2X:M26:Y6J:R30:M0X:M0G:LZX:MF0:M9U:M93:860:M7X:M6U:M6I:M5X:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:MZF:N0F:N0X:N1U:N2X:N3I:N3R:N43:N4L:N5L:N6X:N7L:N8X:N9I:NB0:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NQO:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:NZK:O0C:O0R:O0X:O1I:O1X:O2R:O3I:Z26:O87:O8L:O9O:O9X:OAO:OBO:OCI:OD7:ODX:OE6:OEO:OFX:OGF:OHC:OI4:OIE:OIK:OIX:OJ9:OK9:OKW:OLX:ONU:OGV:OGO:OO6:OPU:OQF:OQL:OQX:ORR:OSI:OT6:OTV:OV4:OVF:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PVR:PWR:PZ6:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4R:Q5C:Q5K:Q5R:Q60:Q7C:Q8O:Q99:QBR:QC3:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QFU:QG3:QGC:QGO:QGX:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QX9:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZ0:QZC:QZL:QZU:R08:R0F:R0Q:R1I:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLH:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RR0:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:XWH:XWZ:Y2C:Y25:Y1R:XZI:XZ6:XXN:V7G:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:G65:X7V:0EN:XEY:XF1:XF4:XF7:XFD:XNJ:AG7:XTJ:XTM:XTP:XU4:XV4:Y6A:Y6G:YD1:YCV:YHJ:YHI:YMG:YSG:YSP:YSJ:YTM:YU4:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:ASC:U7W:U9H:UQW:UQZ:35J:USZ:V18:4N0:5P9:7IL:90I:90X:V1B:I70:4IT:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZW:5ZT:7VI:7VQ:7VW:7W5:81L:7XT:7Y2:7YB:7YI:7YQ:7YZ:87H:8G9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2D:I2N:NB2:V46:W48:I54:Q56:Y48:N63:S4L:ISG:U88:M0C:O5F:O5O:O69:7XB:3XI:40I:59S:5IW:BOV:I8H:IFO:XNV:V9R:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U1J:U2B:U2I:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:OW1:YFK:K9U:06Q:0AX:LVX:OF9:VQR:VQN:83F:83N:84C:83W:YQN:KKO:XI0:XH9:XHW:XJ9:I3R:WZK:ZQB:JVX:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 CL R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-like proteinase[11 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:FMT:IMD:EDO:GOL:GLY:PGE 0 0 0 0 0 0 0 35 0 65 0 0 0 0 0 0 0 0 0 0 142 N T e 104.8 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:Leupeptin[4 aa]:UAW243[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Calpain I Inhibitor[4 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] K0G:GWS:SZY:AWP:T1V:T1Y:T2G:T2J:T2V:T2Y:T3G:T3J:T3V:T47:T4D:T4J:T4M:T4V:T4Y:T54:T5V:T67:JGG:T6M:T6V:T6Y:T71:T7A:T7D:T7G:T7J:T7P:T7S:T7Y:T81:T84:T8A:T8D:T8J:T8M:T8P:T8S:T8V:T8Y:T9J:T9M:T9P:U0P:U0V:U0Y:U1D:U1A:U1G:U1M:UHS:UGD:UGG:UGM:UGP:UH1:UH4:UGV:UH7:UHA:UHV:UHY:UJ1:UHM:UJ4:USD:USA:UPD:UPJ:VEG:VEJ:VEM:VEP:VEV:VEY:O3R:O46:O4F:FHR:FJC:3WL:X77:U5G:K36:UED:B1S:V2M:QYS:SV6:NNA:V7G:O6K:P6N:Q5T:FUA:R6Q:R7Q:R8H:SIN:RMZ:RV5:RV8:RY5:S8B:93J:S8T:SQ2:SQ5:SYH:T0W:ALD:TU8:GQU:H3F:EOF:H60:H63:H6F:H6L:H6R:HUR:HUO:HYR:J7R:J7O:2XI:2RI:KFU:KG9:KJI:KJO:KL6:KLR:KMF:KMX:KO9:KOI:KP0:KQ3:KQL:KQX:KS0:KSI:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L2I:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L8F:L8O:L93:L9F:L9O:LB0:LBC:LBO:LCU:LDX:LKX:LJO:LJ0:LF3:LR0:LQU:LQ0:LO0:LRC:LRN:LS0:LSF:LT9:LUC:LV9:LVM:LW6:LWO:M4L:M2X:M26:Y6J:R30:M0X:M0G:LZX:LXF:MF0:M9U:M93:860:M7X:M6U:M6I:M5X:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:MWN:MX9:MZF:N0F:N0O:N0X:N1U:N2X:N3I:N3R:N43:N4L:N5L:N6X:N7L:N8X:N9I:NB0:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NQO:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:NZK:O0C:O0R:O0X:O1I:O1X:O2R:O3I:O4L:Z26:O87:O9O:O9X:OAO:OBO:OCI:OD7:ODX:OE6:OEO:OFX:OGF:OHC:OI4:OIE:OIK:OIX:OJ9:OJO:OK9:OKW:OLX:ONU:OGV:OGO:OO6:OOL:OPU:OQF:OQL:OQX:ORR:OSI:OT6:OTV:OV4:OVF:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PVR:PWR:PZ6:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4F:Q4R:Q5C:Q5K:Q5R:Q60:Q6U:Q7C:Q7R:Q8O:Q99:QBR:QC3:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QFU:QG3:QGC:QGO:QGX:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QX9:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZ0:QZC:QZL:QZU:R08:R0F:R0Q:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLH:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RR0:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:XWH:XWZ:Y2C:Y25:Y1R:Y0L:XZ6:0TI:XXN:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:G65:X7V:0EN:XEY:XF1:XF4:XF7:XFD:XNJ:AG7:XTJ:XTM:XTP:XU4:XV4:Y6A:Y6G:YD1:YCV:YHJ:YHI:YMG:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:ZL7:ASC:U7W:U9H:UQW:UQZ:35J:USZ:V18:4N0:5P9:7IL:90I:90X:V1B:I70:4IT:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZW:5ZT:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7YB:7YI:7YQ:7YZ:87H:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2D:I2N:NB2:V46:W48:I54:Q56:Y48:N63:S4L:ISG:M0C:O5F:O5O:O69:5IL:ODN:7XB:3XI:40I:59S:5IZ:5IW:G7L:BOV:I8H:IFO:XNV:V9R:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:OZI:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U1J:U2B:U2I:SRU:SVL:T2L:T43:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LVX:OF9:ILE:VQR:VQN:83F:83N:84C:83W:YQN:KKO:XI0:XH9:XHW:XJ9:I3R:A1W:WZK:ZQB:JVX:JJC:JJO:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 CL R1AB_SARS2:R1A_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[301 aa]:3C-like proteinase[304 aa]:3C-like proteinase[305 aa]:3C-like proteinase[11 aa] DMS:IMD:EDO:GOL:IPA:FMT:PEG:PO4:PGE 26 40 0 0 0 0 0 0 0 0 0 29 0 0 0 6 0 0 0 0 143 G T e 27.4 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:Leupeptin[4 aa]:UAW243[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Calpain I Inhibitor[4 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] T1V:T1Y:T2G:T2J:T2V:T2Y:T3G:T3J:T3V:T47:T4D:T4J:T4M:T4V:T4Y:T6M:T6V:T6Y:T71:T7A:T7D:T7G:T7J:T7P:T7S:T7Y:T81:T84:T8A:T8D:T8J:T8M:T8P:T8S:T8V:T8Y:T9M:T9P:U0P:U0Y:U1D:U1A:U1G:U1M:UHS:UHV:UHY:UJ1:UHM:UJ4:USD:USA:UPD:UPJ:VEG:VEJ:VEM:VEP:VEV:VEY:FHR:FJC:3WL:X77:U5G:K36:UED:NEN:V2M:QYS:SV6:NNA:V7G:O6K:Q5T:FUA:R8H:SIN:RNW:RY5:SQ5:MYC:ALD:JRY:GQU:H3F:EOF:H60:H63:H6F:H6L:H6R:HER:HUR:HUO:HYR:J7R:J7O:2XI:2RI:KMF:KMX:KSI:KW9:KZC:L1F:L8F:L8O:L93:LQU:LO0:LRN:LW6:M2X:LZX:LXF:M5X:MWN:MX9:MZF:N1U:N2X:N3R:N43:N4L:NB0:O3U:O4L:O5C:O87:OIK:OIX:OJO:OK9:OLX:ONU:OGO:OOL:OVX:P0X:PZ6:Q0I:Q2U:Q4F:Q5R:Q60:Q6U:Q7C:Q7R:Q99:QBR:P3L:QML:QVJ:QM3:RIJ:XZ6:0TI:XXN:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:X7V:0EN:XEY:XF1:XF4:XF7:XFD:AG7:XTJ:XTM:XTP:XU4:XV4:YD1:YCV:YHJ:YHI:YMG:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:ZL7:ASC:U9H:UQW:35J:USZ:V18:7IL:90I:90X:V1B:I70:4IT:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZW:5ZT:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7YB:7YI:7YQ:7YZ:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:I1W:I1Z:NB2:V46:W48:I54:Q56:Y48:N63:S4L:M0C:O5F:O5O:O69:5IL:7XB:3XI:40I:59S:5IZ:5IW:G7L:G7O:BOV:I8H:IFO:XNV:V9R:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:OZI:QQL:QH0:P8U:PJR:QAO:U1J:SRU:SVL:T2L:T43:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LVX:LKR:OF9:ILE:VQR:VQN:83F:83N:84C:83W:YQN:KKO:XH9:XHW:I3R:A1W:ZQB:JVX:JJC:JJO:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 CL:9JT:AU R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] EDO:DMS:ACY:ALA 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144 S b 3.1 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:Leupeptin[4 aa]:UAW243[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Calpain I Inhibitor[4 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] SZY:AWP:T1V:T1Y:T2G:T2J:T2V:T2Y:T3G:T3J:T3V:T47:T4D:T4J:T4M:T4V:T4Y:T5V:T6M:T6V:T6Y:T71:T7A:T7D:T7G:T7J:T7P:T7S:T7Y:T81:T84:T8A:T8D:T8J:T8M:T8P:T8S:T8V:T8Y:T9J:T9M:T9P:U0P:U0Y:U1D:U1A:U1G:U1M:UHS:UGD:UGG:UGM:UGP:UH1:UH4:UH7:UHA:UHV:UHY:UJ1:UHM:UJ4:USD:USA:UPD:UPJ:VEG:VEJ:VEM:VEP:VEV:VEY:O4F:FHR:FJC:3WL:X77:U5G:K36:UED:B1S:V2M:QYS:SV6:NNA:V7G:O6K:P6N:Q5T:R7Q:R8H:SIN:RNW:RY5:S8B:S8T:SQ5:MYC:ALD:TU8:JRY:GQU:EOF:H60:H63:H6F:H6L:H6R:HER:HUR:HUO:HYR:J7R:J7O:2XI:2RI:KFU:KG9:KJO:KLR:KMF:KMX:KO9:KOI:KP0:KQ3:KQL:KQX:KS0:KSI:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KX9:KXR:KYU:KZC:KZX:L1F:L2I:L3I:L6R:L6D:L4U:L7Q:L7V:L83:L8F:L8O:L93:L9F:L9O:LBC:LBO:LCU:LDX:LKX:LJO:LF3:LR0:LQU:LQ0:LO0:LRC:LRN:LS0:LSF:LT9:LUC:LV9:LVM:LW6:LWO:M4L:M2X:Y6J:R30:M0X:M0G:LZX:LXF:MF0:M9U:M93:860:M7X:M6U:M6I:M5X:M5I:M50:MJR:MKI:MVR:MVX:MWN:MX9:MZF:N0F:N0O:N1U:N2X:N3I:N3R:N43:N4L:N5L:N6X:N7L:N8X:N9I:NB0:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:NZK:O0C:O0R:O0X:O1I:O1X:O2R:O3I:O3U:O4L:O5C:Z26:O87:O8L:O9O:O9X:OAO:OBO:OCI:ODX:OE6:OEO:OFX:OHC:OI4:OIE:OIK:OIX:OJ9:OJO:OK9:OKW:OLX:ONU:OGV:OGO:OOL:OPU:OQF:OQL:OQX:ORR:SQ2:OSI:OT6:OTV:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P9O:PJ6:PJX:PUU:PZ6:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q4F:Q5C:Q5K:Q5R:Q60:Q6U:Q7R:Q99:QBR:QC3:P7R:PQ6:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QFU:QG3:QGC:QGO:QGX:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QX9:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZ0:QZC:QZL:QZU:R08:R0F:R0Q:R1I:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLH:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RR0:RRD:RRU:RS6:RSL:RT4:RT9:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:XWH:XWZ:Y2C:Y25:Y1R:XZ6:0TI:XXN:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:G65:X7V:0EN:XEY:XF1:XF4:XF7:XFD:XNJ:AG7:XTJ:XTM:XTP:XU4:XV4:Y6G:YD1:YCV:YHJ:YHI:YMG:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:ZL7:ASC:U7W:U9H:UQW:UQZ:35J:USZ:V18:4N0:5P9:7IL:90I:90X:V1B:I70:GWS:4IT:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZW:5ZT:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7YB:7YI:7YQ:7YZ:87H:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2N:NB2:V46:W48:I54:Q56:Y48:N63:S4L:M0C:O5F:O5O:O69:5IL:7XB:3XI:40I:59S:5IZ:5IW:BOV:I8H:IFO:XNV:V9R:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:OZI:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U1J:U2B:U2I:SRU:SVL:T2L:T43:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LVX:LKR:OF9:VQR:83F:83N:84C:83W:YQN:KKO:XI0:XH9:XHW:XJ9:I3R:A1W:WZK:ZQB:JVX:JJC:JJO:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 CL:ZN:AU R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] DMS:EDO:FMT:IMD:GLY:ACY 39 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 11 0 0 0 145 C T b 16.0 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:Leupeptin[4 aa]:UAW243[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Calpain I Inhibitor[4 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] K0G:GWS:SZY:AWP:T1V:T1Y:T2G:T2J:T2V:T2Y:T3G:T3J:T3V:T47:T4D:T4J:T4M:T4V:T4Y:T5V:T67:T6M:T6V:T6Y:T71:T7A:T7D:T7G:T7J:T7P:T7S:T7V:T7Y:T81:T84:T8A:T8D:T8J:T8M:T8P:T8S:T8V:T8Y:T9J:T9M:T9P:U0P:U0V:U0Y:U1D:U1A:U1G:U1M:UHS:UGD:UGG:UGM:UGP:UH1:UH4:UGV:UH7:UHA:UHV:UHY:UJ1:UHM:UJ4:USD:USA:UPD:UPJ:VEG:VEJ:VEM:VEP:VEV:VEY:O46:O4F:FHR:FJC:3WL:X77:U5G:K36:UED:B1S:NEN:V2M:QYS:SV6:NNA:V7G:O6K:P6N:Q5T:FUA:R7Q:R8H:SIN:RNW:RV8:RY5:S8B:S8T:SQ2:SQ5:MYC:SYH:T0W:PK8:ALD:TU8:JRY:GQU:H3F:EOF:H60:H63:H6F:H6L:H6R:HER:HUR:HUO:HYR:J7R:J7O:2XI:2RI:KFU:KG9:KJI:KJO:KLR:KMF:KMX:KNU:KO9:KOI:KP0:KQ3:KQL:KQX:KS0:KSI:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L2I:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L8F:L8O:L93:L9F:L9O:LB0:LBC:LBO:LCU:LDX:LKX:LKI:LJO:LJ0:LF3:LR0:LQU:LQ0:LO0:LM0:LRC:LRN:LS0:LSF:LT9:LUC:LVM:LW6:LWO:M4L:M2X:M26:Y6J:R30:M0X:M0G:LZX:LXF:MF0:M9U:M93:860:M7X:M6U:M6I:M5X:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:MWN:MX9:MZF:N0F:N0O:N0X:N1U:N2X:N3I:N3R:N43:N4L:N5L:N6X:N7L:N8X:N9I:NB0:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NQO:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NYR:NZK:O0C:O0R:O0X:O1I:O1X:O2R:O3I:O3U:O4L:O5C:Z26:O87:O9O:O9X:OAO:OBO:OCI:OD7:ODX:OE6:OEO:OFX:OGF:OHC:OI4:OIE:OIK:OIX:OJ9:OJO:OK9:OKW:OLX:ONU:OGV:OGO:OO6:OOL:OPU:OQF:OQL:OQX:ORR:OSI:OT6:OTV:OV4:OVF:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PVR:PZ6:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4F:Q4R:Q5C:Q5K:Q5R:Q60:Q69:Q6U:Q7C:Q7R:Q8O:Q99:QBR:QC3:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QG3:QGC:QGO:QGX:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZ0:QZC:QZL:QZU:R08:R0F:R0Q:R1I:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLH:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RR0:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:XWH:XWZ:Y2C:Y25:Y1H:XZ6:0TI:XXN:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:G65:X7V:XC4:0EN:XEY:XF1:XF4:XF7:XFD:XNJ:AG7:XTJ:XTM:XTP:XU4:XV4:XWS:Y6A:Y6G:YD1:YCV:YHJ:YHI:YMG:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:ZL7:ASC:U7W:U9H:UQW:35J:USZ:V18:4N0:5P9:7IL:90I:90X:V1B:I70:4IT:4IJ:4I9:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZW:5ZT:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7Y2:7YB:7YI:7YQ:7YZ:87H:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2D:I2N:NB2:V46:W48:I54:Q56:Y48:N63:S4L:ISG:U88:M0C:O5F:O5O:O69:5IL:ODN:7XB:3XI:40I:59S:5IZ:5IW:G7L:G7O:9FF:BOV:I8H:IFO:XNV:V9R:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:OZI:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U1J:U2B:U2I:SRU:SVL:T2L:T43:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LVX:LKR:OF9:VQR:VQN:83F:83N:84C:83W:YQN:KKO:XI0:XH9:XHW:XJ9:I3R:A1W:WZK:ZQB:JVX:JJC:JJO:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 CL:SE:9JT:AU:ZN:NA R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] DMS:EDO:FMT:IMD:GLY:ACY:ALA 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146 G T b 0.0 6xbi_A ZN 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147 S b 0.0 6xbi_A NA 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 148 V E b 0.0 6xbi_A NA 0 0 0 0 0 0 0 0 0 0 0 0 32 0 0 0 0 68 0 0 149 G E b 0.0 6xbi_A 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150 F E b 0.0 6xbi_A 0 0 0 0 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 151 N E b 20.0 6xbi_A CL R1AB_SARS2:3C-like proteinase[298 aa] EDO:DMS 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 0 16 35 0 0 152 I E b 5.3 6xbi_A EDO:GOL 0 0 0 5 0 0 0 43 5 27 8 0 0 5 0 0 0 6 0 0 153 D E e 34.0 6xbi_A LZE ZN R1AB_SARS2:3C-like proteinase[298 aa] EDO 0 0 11 36 0 0 0 0 6 0 6 25 0 0 6 0 11 0 0 0 154 Y T e 36.1 6xbi_A R1AB_SARS2:3C-like proteinase[298 aa] EDO:GOL 0 0 0 0 0 40 0 0 15 0 0 35 0 0 0 0 0 0 0 11 155 D T b 13.0 6xbi_A S7D ZN EDO 0 0 33 0 0 49 0 0 8 0 0 5 0 0 0 5 0 0 0 0 156 C E b 16.0 6xbi_A NEN:S8H:9JT:HYR:U88 AU:ZN EDO:DMS:GOL 0 16 0 14 0 0 0 5 0 0 0 0 0 0 0 11 17 37 0 0 157 V E b 0.0 6xbi_A HYR 0 0 0 0 0 0 0 16 0 11 0 0 0 0 0 0 0 74 0 0 158 S E b 10.2 6xbi_A R1AB_SARS2:3C-like proteinase[298 aa] EDO 0 0 0 24 0 0 0 0 11 0 0 30 0 8 5 11 0 0 0 11 159 F E b 0.0 6xbi_A 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 160 C E b 0.0 6xbi_A 0 47 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 38 0 0 161 Y E b 0.9 6xbi_A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 162 M E b 0.0 6xbi_A 0 0 0 0 0 0 0 0 0 20 80 0 0 0 0 0 0 0 0 0 163 H E b 2.1 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:UAW243[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] K0G:GWS:SZY:AWP:T2G:T47:T4Y:T5V:T67:T6Y:T81:T84:T8A:T8J:T8M:T9J:U0P:U0V:U1G:UHS:UGD:UGG:UGM:UGP:UH1:UH4:UGV:UH7:UHA:UHV:UHY:UJ1:UHM:UJ4:VEG:VEJ:VEM:VEP:VEV:VEY:O4F:FHR:FJC:X77:K36:UED:B1S:V2M:QYS:NNA:U5G:V7G:O6K:P6N:Q5T:SV6:R7Q:R8H:RV8:RY5:S8B:S8T:SQ2:SQ5:SYH:T0W:ALD:TU8:GQU:EOF:H60:H63:H6F:H6L:H6R:HUR:HUO:J7R:J7O:2XI:2RI:KFU:KG9:KJI:KJO:KLR:KO9:KOI:KP0:KQ3:KQL:KQX:KS0:KSI:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L2I:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L8F:L8O:L93:L9F:L9O:LB0:LBC:LBO:LCU:LDX:LKX:LJO:LJ0:LF3:LR0:LQ0:LO0:LRC:LS0:LSF:LT9:LUC:LV9:LVM:LWO:M4L:M2X:M26:Y6J:R30:M0X:M0G:LZX:LXF:MF0:M9U:M93:860:M7X:M6U:M6I:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:MZF:N0F:N0O:N0X:N1U:N2X:N3I:N3R:N43:N4L:N5L:N6X:N7L:N8X:N9I:NB0:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NQO:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:NZK:O0C:O0R:O0X:O1I:O1X:O2R:O3I:O5C:Z26:O87:O8L:O9O:O9X:OAO:OBO:OCI:OD7:ODX:OE6:OEO:OFX:OGF:OHC:OI4:OIE:OIK:OIX:OJ9:OJO:OK9:OKW:OLX:ONU:OGV:OGO:OO6:OPU:OQF:OQL:OQX:ORR:OSI:OT6:OTV:OV4:OVF:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PVR:PWR:PZ6:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4R:Q5C:Q5K:Q5R:Q60:Q7C:Q7R:Q8O:Q99:QBR:QC3:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QFU:QG3:QGC:QGO:QGX:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QX9:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZ0:QZC:QZL:QZU:R08:R0F:R0Q:R1I:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLH:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RR0:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:XWH:XWZ:Y2C:Y25:Y1R:XZ6:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:G65:X7V:0EN:XEY:XF1:XF4:XF7:XFD:XNJ:AG7:XTJ:XTM:XTP:XU4:XV4:Y6A:Y6G:YD1:YCV:YHJ:YHI:YMG:YSG:YSP:YSJ:YU4:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:ASC:U7W:U9H:UQW:UQZ:35J:USZ:V18:4N0:5P9:7IL:90I:90X:V1B:I70:4IT:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZW:5ZT:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7Y2:7YB:7YI:7YQ:7YZ:87H:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2D:I2N:NB2:V46:W48:I54:Q56:Y48:N63:S4L:ISG:M0C:O5F:O5O:O69:7XB:3XI:40I:59S:5IZ:5IW:9FF:BOV:I8H:XNV:V9R:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:OZI:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U2B:U2I:T4V:SVL:T2L:T43:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LVX:OF9:VQR:VQN:83F:83N:84C:83W:YQN:KKO:XI0:XH9:XHW:XJ9:I3R:A1W:WZK:ZQB:JVX:JJC:JJO:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 ZN R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] DMS:EDO:FMT:IMD:GLY 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 164 H E b 4.2 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:Leupeptin[4 aa]:UAW243[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Calpain I Inhibitor[4 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE..:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] JFM:HWH:RZS:K0G:GWS:SZY:T0Y:T2G:T2V:T3J:T47:T4V:T4Y:T54:NTG:T67:JGG:T6M:T6V:T7A:T7J:T7V:T7Y:T81:T84:T8A:T8M:T8V:T8Y:T9J:U0M:U0P:U0Y:U1D:U1G:U1M:UHS:UGD:UGG:UGM:UGP:UGS:UH1:UGV:UH7:UHA:UHV:UHY:UJ1:UHM:UJ4:US7:VEG:VEJ:VEM:VEP:VEV:VEY:O46:FHR:FJC:3WL:X77:U5G:K36:UED:B1S:V2M:QYS:SV6:NNA:V7G:O6K:P6N:Q5T:FUA:R7Q:R8H:SIN:CB1:RNW:RV8:RY5:S1W:S8B:S8T:SQ2:SQ5:MYC:SYH:T0W:PK8:ALD:TU8:JRY:GQU:H3F:EOF:H60:H63:H6F:H6L:H6R:HER:HUR:HUO:J7R:2XI:2RI:KFU:KG9:KJI:KJO:KL6:KLR:KMF:KNU:KO9:KOI:KP0:KQ3:KQL:KQX:KS0:KSI:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L2I:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L8F:L8O:L93:L9F:L9O:LB0:LBC:LBO:LCU:LDX:LKX:LKI:LJO:LJ0:LF3:LR0:LQU:LQ0:LO0:LM0:LRC:LRN:LS0:LSF:LT9:LUC:LVM:LWO:M4L:M2X:M26:Y6J:R30:M0X:M0G:LZX:MF0:M9U:M93:860:M7X:M6U:M6I:M5X:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:MWN:MX9:MZF:N0F:N0O:N0X:N1U:N2X:N3I:N3R:N43:N4L:N5L:N6X:N7L:N8X:N9I:NB0:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NQO:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:NZK:O0C:O0R:O0X:O1I:O1X:O2R:O3I:O3U:O5C:Z26:O8L:O9O:O9X:OAO:OBO:OCI:OD7:ODX:OE6:OEO:OFX:OGF:OHC:OI4:OIE:OIK:OIX:OJ9:OK9:OKW:OLX:ONU:OGV:OGO:OO6:OOL:OPU:OQF:OQL:OQX:ORR:OSI:OT6:OTV:OUF:OV4:OVF:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PVR:PWR:PZ6:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4F:Q4R:Q5K:Q5R:Q60:Q69:Q6U:Q7C:Q7R:Q8O:Q99:QBR:QC3:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QFU:QG3:QGC:QGO:QGX:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QX9:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZ0:QZC:QZL:QZU:R08:R0F:R0Q:R1I:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLH:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RR0:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:Y1L:Y1H:Y0W:Y0L:XZX:0TI:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:G65:X7V:XC4:0EN:XEY:XF1:XF4:XF7:XFD:XNJ:AG7:XTJ:XTM:XTP:XU4:XV4:XWS:Y6A:Y6G:YHJ:YHI:YMG:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:ZL7:U7W:U9H:UQZ:35J:USZ:V18:4N0:5P9:7IL:90I:90X:V1B:I70:4IT:4IJ:4I9:4W8:4WI:5YN:5ZB:5ZF:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7Y2:7YB:7YI:7YQ:7YZ:87H:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2D:I2N:NB2:V46:W48:I54:Q56:Y48:N63:S4L:ISG:U88:M0C:O5F:O5O:O69:5IL:ODN:7XB:3XI:40I:59S:5IZ:5IW:G7L:9FF:BOV:I8H:IFO:XNV:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:OZI:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U1J:U2B:U2I:SRU:T2L:T43:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LVX:LKR:OF9:VQR:VQN:83F:83N:84C:83W:YQN:KKO:XI0:XH9:XHW:I3R:A1W:WZK:ZQB:JVX:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 SE:CL:ZN:NA R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] DMS 0 0 0 0 0 0 42 0 0 0 0 0 0 58 0 0 0 0 0 0 165 M E b 16.9 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:Leupeptin[4 aa]:UAW243[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Calpain I Inhibitor[4 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] JFM:HWH:RZG:RZJ:RZS:K0G:GWS:SZY:LPZ:T0Y:T2G:T3J:T47:T4V:T54:T5G:NTG:T67:JGG:T7V:T84:T8A:T8M:T9J:U0M:U1D:UHS:UGD:UGG:UGM:UGP:UGS:UH1:UH4:UGV:UH7:UHA:UHV:UHY:UJ1:UHM:UJ4:US7:VEG:VEJ:VEM:VEP:VEV:VEY:O46:FHR:FJC:3WL:X77:U5G:K36:UED:B1S:V2M:QYS:SV6:NNA:V7G:O6K:Q5T:FUA:CB1:RNW:RV8:RY5:S8B:SQ2:SQ5:MYC:SYH:T0W:ALD:TU8:JRY:GQU:EOF:H60:H63:H6F:H6L:H6R:HER:HUR:HUO:HYR:J7R:J7O:2XI:2RI:KFU:KG9:KJI:KJO:KL6:KLR:KMF:KNU:KO9:KOI:KP0:KQ3:KQL:KQX:KS0:KSI:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L2I:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L8F:L8O:L93:L9F:L9O:LB0:LBC:LBO:LCU:LDX:LKX:LKI:LJO:LJ0:LF3:LR0:LQU:LQ0:LO0:LM0:LRC:LS0:LSF:LT9:LUC:LV9:LVM:LWO:M4L:M2X:M26:Y6J:R30:M0X:M0G:LZX:MF0:M9U:M93:860:M7X:M6U:M6I:M5X:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:MZF:N0F:N0O:N0X:N1U:N2X:N3I:N3R:N43:N4L:N5L:N6X:N7L:N8X:N9I:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NQO:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:NZK:O0C:O0R:O0X:O1I:O1X:O2R:O3I:O5C:Z26:O87:O8L:O9O:O9X:OAO:OBO:OCI:OD7:ODX:OE6:OEO:OFX:OGF:OHC:OI4:OIE:OIX:OJ9:OJO:OK9:OKW:OLX:ONU:OGV:OO6:OOL:OPU:OQF:OQL:OQX:ORR:OSI:OT6:OTV:OUF:OV4:OVF:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PVR:PWR:PZ6:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4F:Q4R:Q5C:Q5K:Q5R:Q60:Q69:Q7C:Q7R:Q8O:Q99:QBR:QC3:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QFU:QG3:QGC:QGO:QGX:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QX9:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZ0:QZC:QZL:QZU:R08:R0F:R0Q:R1I:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLH:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RR0:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:Y1R:Y1L:Y1H:Y1C:ZHA:Y0W:Y3N:VXQ:NT9:Y0L:Y0H:Y0C:XZX:XZT:XZO:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:G65:X7V:XC4:XEY:XF1:XF4:XF7:XFD:XNJ:AG7:XTJ:XTM:XTP:XU4:XV4:XWS:Y6A:Y6G:YD1:YHJ:YHI:YMG:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:ZL7:ASC:U7W:U9H:UQW:UQZ:35J:USZ:V18:4N0:5P9:7IL:90I:90X:V1B:I70:4IT:4I9:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZT:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7Y2:7YB:7YI:7YQ:7YZ:87H:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2D:I2N:NB2:V46:W48:I54:Q56:Y48:N63:S4L:ISG:U88:M0C:O5F:O5O:O69:5IL:ODN:7XB:3XI:40I:59S:5IZ:5IW:G7L:G7O:BOV:I8H:IFO:XNV:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:OZI:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U1J:U2B:U2I:SRU:SVL:T2L:T43:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LVX:LKR:OF9:VQR:VQN:83F:83N:84C:83W:YQN:KKO:XI0:XH9:XHW:XJ9:I3R:A1W:WZK:ZQB:JVX:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] DMS:GOL:EDO:ACT 0 0 0 0 0 0 0 12 0 61 26 0 0 0 0 0 0 0 0 0 166 E E e 58.8 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:Leupeptin[4 aa]:UAW243[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Calpain I Inhibitor[4 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] HWH:RZG:RZJ:K0G:GWS:SZY:AWP:T54:T5G:T5V:NTG:T67:T9J:U0P:U0V:UHS:UGD:UGG:UGM:UGP:UGS:UH1:UH4:UGV:UH7:UHA:UHV:UHY:UJ1:UHM:UJ4:US7:VEG:VEJ:VEM:VEP:VEV:VEY:O3R:O46:O4F:FHR:FJC:3WL:X77:U5G:K36:UED:B1S:V2M:QYS:SV6:NNA:V7G:O6K:P6N:Q5T:R7Q:R8H:CB1:RV5:RV8:RY5:S8B:S8T:SQ2:SQ5:MYC:SYH:T0W:ALD:TU8:GQU:EOF:H60:H63:H6F:H6L:H6R:HER:HUR:HUO:J7R:J7O:2XI:2RI:KFU:KG9:KJI:KJO:KL6:KLR:KO9:KOI:KP0:KQ3:KQL:KQX:KS0:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L2I:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L8F:L93:L9F:L9O:LB0:LBC:LBO:LCU:LDX:LKX:LJO:LJ0:LF3:LR0:LQ0:LO0:LM0:LRC:LS0:LSF:LT9:LUC:LV9:LVM:LWO:M4L:M2X:M26:Y6J:R30:M0X:M0G:LZX:MF0:M9U:M93:860:M7X:M6U:M6I:M5X:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:MZF:N0F:N0O:N0X:N1U:N2X:N3I:N3R:N43:N4L:N5L:N6X:N7L:N8X:N9I:NB0:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NQO:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:NZK:O0C:O0R:O0X:O1I:O1X:O2R:O3I:Z26:O87:O8L:O9O:O9X:OAO:OBO:OCI:OD7:ODX:OE6:OEO:OFX:OGF:OHC:OI4:OIE:OIK:OIX:OJ9:OK9:OKW:OLX:ONU:OGV:OGO:OO6:OPU:OQF:OQL:OQX:ORR:OSI:OT6:OTV:OV4:OVF:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PVR:PWR:PZ6:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4R:Q5C:Q5K:Q5R:Q60:Q7C:Q8O:Q99:QBR:QC3:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QFU:QG3:QGC:QGO:QGX:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QX9:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZ0:QZC:QZL:QZU:R08:R0F:R0Q:R1I:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLH:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RR0:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:XWH:XWZ:Y2C:Y25:Y1R:Y0L:XZX:XZT:XZO:XZ6:XXN:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:G65:X7V:0EN:XEY:XF1:XF4:XF7:XFD:XNJ:AG7:XTJ:XTM:XTP:XU4:XV4:XWS:Y6A:Y6G:YD1:YCV:YHJ:YHI:YMG:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:ZL7:ASC:U7W:U9H:UQW:UQZ:35J:USZ:V18:4N0:5P9:7IL:90I:90X:V1B:I70:4IT:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZW:5ZT:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7Y2:7YB:7YI:7YQ:7YZ:87H:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2D:I2N:NB2:V46:W48:I54:Q56:Y48:N63:S4L:ISG:M0C:O5F:O5O:O69:ODN:7XB:3XI:40I:59S:5IZ:5IW:BOV:I8H:IFO:XNV:V9R:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:OZI:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U1J:U2B:U2I:T2L:T43:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LVX:LKR:OF9:VQR:VQN:83F:83N:84C:83W:YQN:KKO:XI0:XH9:XHW:XJ9:WZK:ZQB:JVX:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 NI R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[307 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[300 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-like proteinase[11 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:EDO:FMT:IMD:GLY:GOL:SCN:ACT 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167 L b 3.4 6xbi_A R1AB_SARS2:R1A_SARS2:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:nsp5/6 peptidyl substrate[9 aa]:Non-structural protein 4 peptide[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 12/13[8 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa] HWH:UGD:UGS:VEM:O3R:U5G:SV6:NNA:O6K:CB1:RV5:ALD:GQU:H6F:H6L:KG9:KS0:KT9:KWR:KXR:L8F:LSF:LUC:O8L:O9O:ONU:OQX:OVF:Q99:QBR:QCC:R43:R8I:R9R:RFF:RNI:RRU:RT9:S0X:S1U:S4X:S5L:S6K:S7C:S7U:XZX:XZT:XZO:GHX:VHJ:XM2:TG3:XF1:XF7:XFD:AG7:YMG:YSG:YSP:YSJ:YU4:YVP:YVY:YVD:YVG:YVJ:YVM:YVV:I70:UJ1:4IT:4WI:7VW:7W5:8G9:8GW:I71:8H9:I69:8I7:91Z:99W:FIK:I1W:I1Z:NB2:Y48:M0C:40I:I8H:XNV:MXU:M9X:MFL:MIJ:MJ0:OW1:T2L:T43:U76:X6O:X70:X6T:X9Z:XA8:Y8O:83W:ZQB:JK0:WOK:WTV:X83:X8F:XKQ DMS:EDO:GOL:ACT 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 168 P T e 94.6 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW248[5 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] HWH:RZG:RZJ:T5G:UGD:UGS:UHV:UHY:UJ1:UJ4:VEG:VEM:O3R:U5G:K36:B1S:V2M:QYS:SV6:NNA:V7G:O6K:CB1:RV5:ALD:GQU:EOF:H60:H63:H6F:H6L:H6R:HUR:HUO:KG9:KL6:KS0:KT9:KWR:KXR:L8F:LSF:LUC:O3I:O8L:O9O:OCI:ONU:Q45:Q99:QCC:QOO:QRF:R43:R8I:R9R:RFF:RNI:RRU:RT9:S1U:S5L:S6K:S7C:S7U:XZX:XZT:XZO:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:XF4:XF7:XFD:AG7:XTJ:XV4:YHJ:YMG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVJ:YVV:YWJ:ZJ1:USZ:I70:4IT:4W8:4WI:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7YI:7YQ:7YZ:8G9:8UI:I80:91I:91Z:99W:FIK:I1W:I1Z:NB2:Y48:ISG:M0C:3XI:40I:59S:5IZ:5IW:I8H:XNV:MXU:M9X:MFL:MIJ:MJ0:OW1:QQL:QAO:T2L:T43:U76:X70:X6T:XA8:YFK:83F:83N:83W:ZQB:JK0:WOK:WTE:WTV:A1ADS CL R1AB_SARS2:R1A_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[306 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase[11 aa] DMS:EDO 5 0 0 0 0 35 0 0 0 0 0 0 33 0 0 27 0 0 0 0 169 T T e 74.0 6xbi_A R1AB_SARS2:R1A_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[307 aa]:3C-like proteinase[306 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[303 aa] DMS 0 0 0 0 0 0 0 0 0 0 0 49 0 0 0 24 27 0 0 0 170 G S e 39.3 6xbi_A R1AB_SARS2:ARG-GLU-PRO-MET-LEU-GLN[6 aa] T5D:S1U R1AB_SARS2:R1A_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[306 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[307 aa]:3C-like proteinase[303 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:3C-like proteinase[301 aa]:Main Protease[305 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:3C-like proteinase[300 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[304 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:3C-Like Protease[304 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-Like Protease[306 aa]:Replicase polyprotein 1ab[306 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] GOL:DMS 15 0 0 0 0 85 0 0 0 0 0 0 0 0 0 0 0 0 0 0 171 V b 6.7 6xbi_A T5D NA R1AB_SARS2:3C-like proteinase[307 aa] GOL 6 28 0 0 0 0 0 0 0 15 0 0 0 0 0 17 23 11 0 0 172 H E b 1.6 6xbi_A R1AB_SARS2:NEMO_HUMAN:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] T5D:UGG:FHR:FJC:K36:UED:B1S:V2M:QYS:V7G:O6K:Q5T:RY5:GQU:EOF:H63:H6F:H6L:H6R:HUR:HUO:2XI:KQL:KU6:KW9:KZC:L1F:L93:LO0:LV9:M26:MVX:MZF:N3R:N43:N4L:NB0:Z26:O87:OAO:ONU:OGO:P0X:P3L:PWR:Q2U:Q5R:Q60:Q7C:Q99:QEX:QF5:QGC:QGX:QH6:QHU:QI7:QIQ:QJ6:OI4:PUU:QJR:QKI:QQF:QQO:QR9:QNU:QRS:QSF:QT3:QTC:QTL:QVU:QW1:QX3:QX9:QYN:QYR:QZ0:R08:R1U:R2X:RFR:RG9:RLH:RM3:RN0:RS6:RSL:RVL:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:AG7:XTJ:XTM:XTP:XU4:XV4:YD1:YHJ:YHI:YMG:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:ASC:4N0:5P9:90I:90X:I70:4IT:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:H69:5ZW:5ZT:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7Y2:7YB:7YI:7YQ:7YZ:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:NB2:V46:W48:I54:Q56:Y48:N63:S4L:ISG:M0C:7XB:3XI:40I:59S:5IZ:BOV:I8H:XNV:LQ6:MXU:M9X:MFL:MIJ:MJ0:OW1:QQL:QH0:P8U:PJR:T2L:T43:7YY:U6Y:U76:WOH:Y8O:YFK:K9U:06Q:0AX:0BO:83F:83N:84C:83W:KKO:ZQB:W28:WOK:WTE:A1AD0 R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:FMT:EDO:GLY 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 173 A E b 0.9 6xbi_A NA 11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55 35 0 0 174 G E b 1.2 6xbi_A NA 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175 T E b 0.0 6xbi_A 0 5 0 0 0 0 0 0 0 0 0 0 0 0 0 45 50 0 0 0 176 D b 7.4 6xbi_A JJG:T1S:HV2:K1G:RQH NA 10 0 67 0 0 0 0 0 0 0 0 11 0 0 0 11 0 0 0 0 177 L T b 1.1 6xbi_A 0 0 0 0 57 0 0 0 0 37 6 0 0 0 0 0 0 0 0 0 178 E T b 15.6 6xbi_A JJG:T1S:HV2:K1G:RQH NA R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[305 aa] GOL:EDO:DMS 0 0 34 21 0 0 0 0 0 0 15 11 0 0 0 13 6 0 0 0 179 G S b 0.0 6xbi_A 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180 N e 43.0 6xbi_A NA R1AB_SARS2:3C-like proteinase[306 aa] EDO:DMS:PEG:NO3:GOL 0 0 6 26 0 0 0 0 5 0 0 16 0 0 0 6 11 30 0 0 181 F B b 8.1 6xbi_A UH1:KO9:KSX:N6X:Q36:P5X:P7L:WZK R1AB_SARS2:3C-like proteinase[306 aa] EDO:GOL:DMS:PEG:NO3 0 0 0 0 50 0 0 0 0 0 44 0 0 0 0 0 0 6 0 0 182 Y S b 0.4 6xbi_A LWA NA GOL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 183 G T e 32.1 6xbi_A LWA R1AB_SARS2:3C-like proteinase[306 aa] GOL:PEG:EDO 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184 P T e 84.5 6xbi_A LWA:5F8:JAH CL R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[305 aa] FMT:EDO:DMS:GOL:PEG 16 0 0 0 0 37 0 0 6 0 0 6 35 0 0 0 0 0 0 0 185 F b 4.8 6xbi_A NNA:H6L:5F8:SV6 NA FMT:EDO:DMS:GOL 0 0 0 0 46 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54 186 V e 38.0 6xbi_A Nonstructural protein 5/6[9 aa]:Macrocyclic peptide inhibitor[15 aa] SFY:FJC:NNA:SV6:OZC:QD9:QO0:Y1L:VXQ:NT9:Y0C:5F8:JAH:Y6A:Y6J:H37:YVP:YVD:YVG:YVJ:YVM:I2D:LQ6:P5X:P6I:P6R:P7L:06Q:XI0:XH9:XHW:XJ9:WZK EDO:DMS:1PE 0 0 6 47 0 0 0 0 6 0 5 0 0 0 11 0 0 26 0 0 187 D S b 8.6 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:Leupeptin[4 aa]:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp15/16 peptidyl substrate[8 aa]:Calpain I Inhibitor[4 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Macrocyclic peptide inhibitor[15 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] JFM:HWH:RZG:RZJ:RZS:GWS:LPZ:T2V:T47:T54:T5G:T67:JGG:T7V:T9J:U0M:U1D:UGM:UGP:UH1:UGV:UH7:UHA:UJ4:VEG:VEJ:VEM:VEP:VEV:VEY:O46:FHR:FJC:3WL:X77:U5G:UED:K36:B1S:V2M:QYS:SV6:NNA:V7G:O6K:FUA:CB1:RNW:RY5:S1W:SQ2:SQ5:MYC:SYH:T0W:ALD:9JT:TU8:JRY:GQU:EOF:H6F:H6L:H6R:HER:HUR:HUO:HYR:J7R:J7O:2RI:KFU:KG9:KJO:KMF:KNU:KO9:KOI:KP0:KQ3:KQL:KQX:KSI:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L8F:L8O:L93:L9F:LB0:LBC:LBO:LCU:LDX:LKX:LKI:LJ0:LF3:LR0:LQU:LQ0:LO0:LM0:LRC:LS0:LSF:LT9:LUC:LV9:LVM:LWO:M4L:M2X:M26:Y6J:R30:M0G:MF0:M93:860:M7X:M6U:M6I:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:N0O:N0X:N1U:N3I:N3R:N43:N4L:N5L:N6X:N7L:N8X:N9I:NB0:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NQO:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:O0C:O0R:O0X:O1I:O1X:O2R:O3I:O5C:Z26:O87:O8L:O9O:OAO:OBO:OCI:OD7:ODX:OE6:OEO:OGF:OHC:OI4:OIE:OIK:OIX:OJ9:OJO:OKW:OGV:OO6:OPU:OQL:ORR:OSI:OTV:OUF:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PWR:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4F:Q4R:Q5K:Q5R:Q60:Q69:Q99:QBR:QC3:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QFL:QFU:QG3:QGC:QGO:QGX:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QX9:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZ0:QZC:QZL:QZU:R08:R0F:R0Q:R1I:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLH:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RR0:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:Y1L:Y1H:Y1C:Y0W:Y3N:VXQ:NT9:Y0L:Y0H:Y0C:XZX:0TI:XXN:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:X7V:XC4:0EN:XEY:XF1:XF4:XF7:XFD:XNJ:XTJ:XTM:XTP:XU4:XV4:XWS:Y6A:Y6G:YD1:YHJ:YHI:YMG:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:U7W:U9H:UQZ:USZ:V18:5P9:7IL:V1B:I70:4IT:4IJ:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZW:5ZT:7VB:7VI:7VQ:7W5:81L:7XT:7Y2:7YB:7YI:7YQ:7YZ:87H:8G9:8GW:I71:I69:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2D:I2N:W48:I54:Y48:N63:S4L:ISG:U88:M0C:O5O:7XB:3XI:40I:59S:5IW:G7L:G7O:9FF:I8H:IFO:XNV:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:OZI:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U1J:U2B:SVL:T2L:T43:7YY:U6Y:U76:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LVX:LKR:OF9:VQR:VQN:KKO:XI0:XH9:XHW:XJ9:WZK:ZQB:JVX:JK0:JWI:JKL:JWO:W28:WOK:WTV:X83:X8F:XKQ:A1AD0 CL:NA R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] TRS:DMS 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188 R S e 30.8 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:inhibitor UAW247[3 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:Z-VAD(OMe)-FMK[5 aa]:nsp5/6 peptidyl substrate[9 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:LEUPEPTIN[4 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] JFM:HWH:RZG:RZJ:RZS:K0G:GWS:LPZ:T0Y:T2V:T3J:T47:T4V:T4Y:T54:T5G:T67:SFY:JGG:T7V:T84:T9J:U0M:U1D:UHS:UGD:UGM:UGP:UH1:UH4:UGV:UH7:UHA:UHV:UHY:UJ1:UJ4:T8M:VEG:VEJ:VEM:VEP:VEV:VEY:O46:FHR:FJC:3WL:U5G:B1S:V2M:QYS:SV6:NNA:O6K:Q5T:FUA:CB1:RNW:RY5:S1W:SQ2:SQ5:MYC:SYH:T0W:ALD:TU8:K36:GQU:EOF:H6F:H6R:HER:HUR:HYR:J7R:J7O:2RI:KFU:KG9:KJO:KL6:KMF:KNU:KO9:KOI:KP0:KQ3:KQL:KQX:KSI:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L8F:L8O:L93:L9F:L9O:LB0:LBC:LBO:LCU:LKX:LKI:LF3:LR0:LQU:LQ0:LO0:LM0:LRC:LRN:LS0:LSF:LT9:LUC:LV9:LVM:LWO:M4L:M2X:M26:Y6J:R30:M0X:M0G:LZX:MF0:M93:860:M7X:M6U:M6I:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:N0O:N0X:N1U:N3I:N3R:N43:N4L:N5L:N6X:N8X:N9I:NB0:NB6:N6F:NDI:NEL:NGX:NIJ:NJE:NJU:NKU:NM0:NO0:NOI:NQ3:NQO:NRC:NRX:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:O0C:O0R:O0X:O1I:O2R:O3I:O5C:Z26:O87:O8L:O9O:OAO:OBO:OCI:OD7:ODX:OE6:OEO:OFX:OGF:OHC:OI4:OIE:OIK:OIX:OJO:OKW:ONU:OGV:OO6:OPU:OQF:OQL:OQX:ORR:OSI:OT6:OTV:OUF:OV4:OVF:OVX:OWC:OWX:OYF:OYX:OZC:OZX:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PWR:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4F:Q5K:Q5R:Q60:Q69:Q7R:Q99:QBR:QC3:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QFU:QG3:QGC:QGO:QGX:QH6:QHU:QI4:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QVG:QVJ:QVU:QWL:QWU:QX3:QX9:QXI:QY6:QYI:QYN:QZ0:QZC:QZU:R08:R0Q:R2X:R3I:R66:R6L:R76:R87:RC9:RDK:RDQ:RDX:REU:RFF:RG3:RI1:RJF:RJO:RJX:RKC:RL0:RNI:RPZ:RQ6:RQF:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:Y1L:Y1H:ZHA:Y0W:Y3N:VXQ:NT9:Y0L:Y0H:Y0C:XZX:XZO:5F8:JAH:0TI:XXN:V7G:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:UED:TG3:X7V:XC4:0EN:XEY:XF1:XF4:XF7:XFD:AG7:XTJ:XTP:XU4:XV4:Y6A:Y6G:YD1:YHJ:YHI:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:U7W:U9H:UQZ:USZ:V18:4N0:5P9:7IL:90I:V1B:I70:4IT:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZF:H69:5ZT:7V2:7VB:7VQ:7VW:7W5:7XT:7Y2:7YB:7YQ:7YZ:87H:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:I1W:I1Z:I2D:I2N:NB2:W48:I54:Y48:N63:S4L:ISG:M0C:O5F:O5O:O69:5IL:7XB:3XI:40I:59S:5IW:G7L:G7O:BOV:I8H:IFO:XNV:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:OZI:QQL:P5X:P6I:P6R:P7L:PJR:QAO:U1J:U2B:SRU:SVL:T2L:T43:7YY:U6Y:U76:X6O:X70:X6T:X9Z:XA8:Y0E:Y8O:YFK:K9U:06Q:0AX:0BO:LKR:OF9:VQN:83F:83N:84C:83W:YQN:KKO:XI0:XH9:XHW:XJ9:A1W:WZK:ZQB:JVX:JWI:JKL:WOK:WTE:WTV:X83:X8F:XKQ:A1AD0 CL R1AB_SARS2:3C-like proteinase[306 aa] DMS:EDO:TRS:GOL:PEG:SCN:ACT:PO4 16 0 0 15 0 0 0 0 18 0 0 0 0 35 16 0 0 0 0 0 189 Q S e 73.5 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW246[4 aa]:inhibitor UAW247[3 aa]:inhibitor UAW248[5 aa]:Leupeptin[4 aa]:UAW243[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:Calpeptin[3 aa]:Z-VAD(OMe)-FMK[5 aa]:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Calpain I Inhibitor[4 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:inhibitor TRIP5[4 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] JFM:HWH:RZG:RZJ:RZS:K0G:GWS:LPZ:T0Y:T2G:T2V:T3J:T47:T4V:T4Y:T5G:T67:JGG:T7V:T84:T8A:T8M:U0M:U1D:U1G:UHS:UGD:UGG:UGM:UGP:UGS:UH1:UH4:UGV:UH7:UHA:UHV:UHY:UJ1:UJ4:US7:UPD:VEG:VEJ:VEM:VEP:VEV:VEY:O3R:O46:O4F:FHR:FJC:3WL:X77:U5G:UED:K36:B1S:V2M:QYS:SV6:NNA:V7G:O6K:Q5T:FUA:CB1:RNW:RV5:RV8:RY5:S1W:S8B:SQ2:SQ5:MYC:SYH:ALD:9JT:TU8:GQU:H3F:EOF:H60:H63:H6F:H6L:H6R:HER:HUR:HUO:HYR:J7R:J7O:2XI:2RI:KFU:KG9:KJO:KL6:KLR:KMF:KNU:KO9:KOI:KP0:KQ3:KQL:KQX:KSI:KSX:KT9:KU6:KUU:KVF:KVO:KVX:KW9:KXF:KWR:KX9:KXR:KY0:KYC:KYU:KZC:KZX:L1F:L2I:L3I:L6R:L6D:L5I:L4U:L4N:L7F:L7Q:L7V:L83:L8F:L8O:L93:L9F:L9O:LB0:LBC:LBO:LCU:LDX:LKX:LKI:LJO:LF3:LR0:LQU:LQ0:LO0:LM0:LRC:LS0:LSF:LT9:LUC:LV9:LVM:LWO:M4L:M26:Y6J:R30:M0X:M0G:LZX:MF0:M9U:M93:860:M7X:M6U:M6I:M5I:M50:MJR:MKI:MQ3:MU3:MVR:MVX:N0F:N0O:N0X:N1U:N2X:N3I:N3R:N43:N4L:N5L:N6X:N8X:NB6:N6F:NDI:NEL:NGX:NJE:NJU:NM0:NO0:NOI:NQ3:NQO:NRC:NSR:NU0:NUR:NV9:NVO:NW0:NWI:NX9:NYR:O0C:O0R:O0X:O1I:O2R:O3I:O5C:Z26:O87:O8L:O9O:O9X:OAO:OBO:OCI:OD7:ODX:OEO:OFX:OGF:OHC:OI4:OIX:OJ9:OJO:OK9:OKW:ONU:OGV:OGO:OO6:OPU:OQF:OQL:OQX:ORR:OSI:OT6:OTV:OUF:OV4:OVF:OVX:OWC:OWX:OYF:OYX:OZC:P0X:P3L:P4R:P6O:P7R:P9O:PJ6:PJX:PKW:PQ6:PUU:PWR:PZ6:Q0I:Q1C:Q1U:Q2G:Q2U:Q36:Q3U:Q45:Q4F:Q4R:Q5C:Q5K:Q60:Q69:Q7R:Q99:QBR:QC3:OZX:QCC:QD4:QD9:QDF:QDU:QE3:QER:QEX:QF5:QFL:QFU:QG3:QGC:QGO:QGX:QH6:QHI:QHU:QI4:QI7:QIM:QIB:QIQ:QIT:QIZ:QJ6:QJL:QJR:QK3:QKI:QKR:QLC:QLO:QM9:QML:QMX:QNU:QO0:QOO:QOC:QQF:QQO:QQU:QR9:QRS:QRF:QS3:QSF:QSX:QT3:QTC:QTL:QU9:QUQ:QV0:QV9:QVG:QVJ:QVU:QW1:QWL:QWU:QX3:QX9:QXI:QXR:QXX:QY6:QYI:QYN:QYR:QZ0:QZC:QZL:QZU:R08:R0F:R0Q:R1I:R1U:R2X:R3I:R43:R4X:R5H:R66:R6L:QM3:R7F:R76:R87:R8I:R8O:R8X:R95:R9E:R9I:R9R:R9Z:RAQ:RBM:RBX:OE6:RC9:RD5:RDK:RDQ:RDX:REU:RFF:RFR:RG3:RG9:RGQ:RGX:RHI:RI1:RIJ:RIY:RJ3:RJF:RJO:RJX:RK6:RKC:RKR:RL0:RL8:RLH:RLR:RM3:RN0:RNI:RPK:RPZ:RQ6:RQO:RQF:RRD:RRU:RS6:RSL:RT4:RT9:RTS:RV0:RVL:RVR:RW0:RW9:RWO:RWT:RXU:RYB:RZF:RZU:S0X:S1U:S1L:S39:S3X:S4X:S5L:S6K:S7C:S7U:Y1L:Y1H:Y1C:ZHA:Y0W:Y3N:VXQ:NT9:Y0L:Y0H:Y0C:XZX:XZT:XZO:0TI:XXN:VJA:GHX:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:X7V:0EN:XEY:XF1:XF4:XF7:XFD:AG7:XTJ:XTM:XTP:XU4:XV4:XWS:Y6A:Y6G:YD1:YHJ:YHI:YMG:YSG:YSP:YSJ:YTM:YU4:H37:YVP:YVY:YVA:YV7:YVD:YVG:YVJ:YVM:YVV:YWJ:C7A:ZJ1:ZL7:U7W:U9H:UQW:UQZ:USZ:V18:4N0:7IL:90I:90X:V1B:I70:4IT:4W8:4WI:5YN:5YJ:5Z7:5Z3:5ZN:5ZJ:5ZB:5ZF:H69:5ZT:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7Y2:7YI:7YQ:7YZ:87H:8G9:8GW:I71:8H9:I69:8I7:8T6:8UI:I80:90U:91I:91Z:99W:FIK:FWI:I1W:I1Z:I2D:I2N:NB2:V46:W48:I54:Q56:Y48:N63:S4L:ISG:M0C:O5F:O5O:O69:5IL:3XI:40I:59S:5IZ:5IW:G7L:G7O:BOV:I8H:IFO:XNV:LQ6:LQL:MXU:M9X:MFL:MIJ:MJ0:OW1:OZI:QQL:QH0:P5X:P6I:P6R:P7L:P8U:PJR:QAO:U1J:U2B:U2I:SRU:SVL:T2L:T43:7YY:U6Y:U76:WOH:X6O:X70:X6T:X9Z:XA8:Y0I:Y0E:Y8O:YFK:06Q:0AX:0BO:LVX:LKR:VQN:83F:83N:84C:83W:YQN:KKO:XI0:XH9:XHW:XJ9:I3R:A1W:WZK:ZQB:JVX:JK0:JWI:JKL:JWO:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 CL R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] DMS:EDO:GOL:FMT:SCN:ACT 0 0 0 15 0 0 0 0 0 0 0 0 35 50 0 0 0 0 0 0 190 T S e 28.6 6xbi_A R1AB_SARS2:NEMO_HUMAN:R1A_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW241[4 aa]:inhibitor UAW248[5 aa]:Leupeptin[4 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:ASN-ARG-ALA-THR-LEU-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:LEUPEPTIN[4 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:nsp7-nsp10 of Replicase polyprotein 1a[10 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] HWH:RZJ:SFY:UGD:UGS:UHV:UJ4:VEG:VEJ:U5G:K36:B1S:V2M:QYS:SV6:NNA:V7G:Q5T:CB1:ALD:GQU:EOF:H63:H6F:H6L:HUR:HUO:J7R:J7O:KT9:KWR:KXR:L8F:LSF:LUC:O3I:O8L:O9O:ONU:Q45:Q99:QBR:QCC:QOO:QRF:XZX:XZT:XZO:JAH:VJA:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:XF1:XF4:XF7:XFD:AG7:XTJ:XU4:XV4:YHJ:YSP:YSJ:YTM:YU4:YVP:YVA:YV7:YVD:YVJ:YVM:YVV:YWJ:USZ:90I:I70:4IT:4W8:4WI:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7Y2:7YB:7YI:7YQ:7YZ:8G9:8GW:I71:8H9:I69:8I7:I80:91I:99W:FWI:I1W:I1Z:I2N:NB2:Y48:ISG:M0C:3XI:40I:59S:BOV:I8H:XNV:O6K:MJ0:OW1:OZI:QQL:QAO:T2L:T43:U6Y:U76:X6O:X70:X6T:X9Z:XA8:Y8O:YFK:83F:83N:84C:83W:ZQB:W28:WOK:WTE:WTV:A1ADS:X83:X8F:XKQ:A1AD0 CL R1AB_SARS2:3C-like proteinase[11 aa] DMS:EDO:GOL:PEG:SCN:ACT 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 17 28 49 0 0 191 A e 95.5 6xbi_A R1AB_SARS2:NEMO_HUMAN:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW248[5 aa]:nsp6/7 peptidyl substrate[10 aa]:nsp15/16 peptidyl substrate[8 aa]:Non-structural protein 4 peptide[6 aa]:Inhibitor 18 in bound form[4 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:LYS-VAL-ALA-THR-VAL-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:3C-like proteinase[5 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:NEMO peptide[9 aa]:Nonstructural protein 4/5[12 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 13/14[10 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:peptide 8-1[10 aa]:Mpro inhibitor[5 aa] SFY:UGS:K36:V2M:QYS:SV6:NNA:V7G:Q5T:ALD:EOF:H63:H6F:H6L:HUR:HUO:ONU:QOO:QRF:XZT:XZO:JAH:VJA:VHV:VHJ:VHM:VHP:XM2:NOL:TG3:XTJ:XU4:XV4:YVA:YVV:YWJ:90I:I70:4IT:4W8:7V2:7VB:7VI:7VQ:7VW:7W5:81L:7XT:7Y2:7YI:7YQ:I80:99W:Y48:ISG:59S:BOV:MJ0:QQL:4WI:U6Y:YFK:ZQB:W28:WTE:WTV:A1ADS CL R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[11 aa] DMS:PEG:GOL 26 0 0 0 0 0 16 0 0 24 11 0 8 0 0 0 0 16 0 0 192 Q b 18.4 6xbi_A R1AB_SARS2:N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-..:inhibitor UAW248[5 aa]:N-[(benzyloxy)carbonyl]-L-valyl-N-[(1S)-1-(carboxy..:nsp4/5 peptidyl substrate[10 aa]:nsp5/6 peptidyl substrate[9 aa]:nsp15/16 peptidyl substrate[8 aa]:Non-structural protein 4 peptide[6 aa]:THR-SER-ALA-VAL-LEU-GLN[6 aa]:SER-GLY-VAL-THR-PHE-GLN[6 aa]:SER-ALA-VAL-LYS-LEU-GLN[6 aa]:ARG-GLU-PRO-MET-LEU-GLN[6 aa]:SER-ALA-VAL-LEU-GLN-SER-GLY-PHE[8 aa]:ACE-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-NH2[10 aa]:ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:Nonstructural protein 4/5[12 aa]:Nonstructural protein 5/6[9 aa]:Nonstructural protein 5/6[10 aa]:Nonstructural protein 7/8[8 aa]:Nonstructural protein 8/9[8 aa]:Nonstructural protein 8/9[10 aa]:Nonstructural protein 9/10[10 aa]:Nonstructural protein 10/11[11 aa]:Nonstructural protein 10/11[10 aa]:Nonstructural protein 12/13[8 aa]:Nonstructural protein 15/16[9 aa]:Z-IETD-FMK[6 aa]:Macrocyclic peptide inhibitor[15 aa]:peptide 8-1[10 aa]:VAL-LYS-LEU-GLN-ALA-VAL-PHE-ARG[8 aa]:VAL-LYS-LEU-GLN-ALA-ILE-PHE-ARG[8 aa]:Mpro inhibitor[5 aa] SFY:UGD:VEG:VEJ:U5G:K36:B1S:SV6:NNA:Q5T:CB1:ALD:H6F:H6L:HUO:J7R:J7O:KT9:KWR:KXR:LSF:LUC:O3I:O8L:O9O:OQX:OV4:OVF:Q99:QBR:QCC:QD9:QO0:QOO:QRF:VXQ:Y0C:XZX:XZT:XZO:5F8:VHJ:VHM:VHP:XM2:NOL:TG3:XF1:XF7:XFD:AG7:YSG:YSP:YSJ:YU4:H37:YVP:YV7:YVD:YVG:YVJ:YVM:YVV:USZ:90I:I70:4WI:7V2:7VB:7VI:7VW:7W5:81L:7XT:7Y2:7YB:7YI:7YQ:7YZ:8G9:8GW:I71:8H9:I69:8I7:91I:99W:I1W:I1Z:I2N:NB2:M0C:3XI:40I:59S:I8H:LQ6:OW1:QAO:T2L:T43:X6O:X70:X6T:X9Z:XA8:Y8O:06Q:83F:83N:84C:83W:KKO:WOK:WTE:WTV:A1ADS:X83:XKQ CL R1AB_SARS2:3C-like proteinase[306 aa] DMS:EDO:GOL:PEG:SCN:ACT 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 193 A e 70.5 6xbi_A H6F:H6L:5F8 CL DMS:EDO 11 0 0 0 0 0 0 6 0 40 0 0 0 0 15 0 0 28 0 0 194 A e 26.8 6xbi_A FMT:EDO 19 0 0 35 0 0 0 0 0 0 0 0 16 16 0 0 0 15 0 0 195 G e 54.8 6xbi_A R1AB_SARS2:3C-like proteinase[305 aa] DMS:FMT:EDO 8 0 0 0 0 33 0 6 0 16 0 0 15 0 0 12 0 11 0 0 196 T e 59.7 6xbi_A T1M:S7V:R9V R1AB_SARS2:3C-like proteinase[305 aa] DMS:EDO:GOL:MPD 24 0 0 0 0 0 0 0 5 0 0 0 23 11 0 5 32 0 0 0 197 D e 40.7 6xbi_A GOL:FMT 0 0 65 0 0 0 0 0 0 0 0 23 0 0 0 12 0 0 0 0 198 T b 19.5 6xbi_A T1J:T1M:S7V:R9V DMS:GOL:FMT:MPD 0 8 0 0 0 0 0 0 16 6 0 21 0 6 0 6 11 11 0 16 199 T B e 20.8 6xbi_A GOL:DMS:FMT 0 0 0 0 0 0 0 6 0 27 23 0 0 0 0 0 24 5 0 16 200 I b 0.0 6xbi_A QGO CL DMS:FMT:GOL:EDO 0 16 0 0 6 0 0 19 0 12 0 0 0 16 0 11 0 21 0 0 201 T H b 0.0 6xbi_A CL 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28 72 0 0 0 202 V H b 8.7 6xbi_A LZE:QGO:GT7 CL DMS:FMT:GOL:EDO 0 0 17 12 0 0 0 10 0 5 0 15 0 0 0 0 0 41 0 0 203 N H b 2.4 6xbi_A LZE:QGO:GT7 CL:NA:ZN 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 204 V H b 0.0 6xbi_A NA:ZN 0 0 0 0 6 0 0 20 0 0 0 0 0 0 0 0 0 74 0 0 205 L H b 0.0 6xbi_A 0 6 0 0 0 0 0 5 0 30 0 0 0 0 0 0 0 59 0 0 206 A H b 0.0 6xbi_A 94 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 207 W H b 2.0 6xbi_A NA:ZN DMS:IPA:PEG:1PE 0 0 0 0 29 0 0 0 0 0 0 0 0 0 0 0 0 0 71 0 208 L H b 0.0 6xbi_A 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 209 Y H b 0.4 6xbi_A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 210 A H b 0.0 6xbi_A 94 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211 A H b 0.0 6xbi_A PEG 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212 V H b 6.7 6xbi_A CL DMS:FMT 0 0 0 0 0 0 0 48 0 29 0 0 0 0 0 0 0 24 0 0 213 I H e 27.5 6xbi_A RMZ:93J:U88 R1AB_SARS2:R1A_SARS2:3C-like proteinase[301 aa]:3C-like proteinase[304 aa] EDO:DMS:FMT:PO4 0 0 0 0 0 0 0 48 0 52 0 0 0 0 0 0 0 0 0 0 214 N T b 4.2 6xbi_A U88 R1AB_SARS2:R1A_SARS2:3C-like proteinase[301 aa]:3C-like proteinase[304 aa]:3C-like proteinase nsp5[304 aa]:3C-like proteinase nsp5[305 aa] EDO:ACT:PEG:PO4:PGE 0 0 0 0 0 0 0 0 0 0 0 77 0 0 0 23 0 0 0 0 215 G T e 50.0 6xbi_A DMS:EDO 0 0 0 0 0 69 0 0 0 0 0 11 0 0 5 0 0 15 0 0 216 D e 25.9 6xbi_A DMS:EDO:PO4 0 44 17 19 0 0 0 0 15 0 0 0 0 0 0 6 0 0 0 0 217 R e 56.9 6xbi_A CL R1AB_SARS2:3C-like proteinase[306 aa] DMS:EDO 11 0 0 0 0 0 0 0 20 0 0 24 0 0 34 0 12 0 0 0 218 W T e 29.1 6xbi_A CL DMS:EDO:SO4:FMT:PO4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 219 F T b 5.3 6xbi_A DMS 1 0 1 1 62 1 0 1 1 1 0 1 1 1 1 1 1 1 24 0 220 L e 24.2 6xbi_A DMS 0 0 0 0 0 0 0 6 0 57 0 0 0 0 0 0 0 37 0 0 221 N e 26.7 6xbi_A MG:NA:K DMS:GOL 0 6 0 15 0 0 0 0 22 0 0 11 0 16 0 12 19 0 0 0 222 R S e 96.4 6xbi_A NA R1AB_SARS2:3C-like proteinase[306 aa] DMS:IMD:GOL 0 0 0 0 0 6 0 0 8 0 0 16 16 0 11 43 0 0 0 0 223 F e 57.9 6xbi_A MG:NA:CL:K:BR GOL:DMS:PEG 0 0 16 6 11 0 0 0 0 0 0 10 0 0 0 14 37 6 0 0 224 T e 57.8 6xbi_A CL:BR:NA DMS:IMD:GOL:PEG 0 0 0 0 0 0 0 0 17 0 0 0 0 0 22 30 26 5 0 0 225 T b 9.7 6xbi_A 0 16 0 0 0 0 0 14 0 6 11 0 0 0 0 0 21 32 0 0 226 T e 46.1 6xbi_A NA EDO:FMT:SO4 6 0 0 0 6 16 0 0 0 0 0 6 0 0 0 49 16 0 0 0 227 L H e 26.4 6xbi_A NA:CL PEG:GOL:FMT:DMS:EDO 0 0 0 0 0 0 0 23 0 27 0 0 8 0 0 0 0 42 0 0 228 N H e 67.9 6xbi_A K1G CL:NA R1AB_SARS2:3C-like proteinase[305 aa] GOL:EDO:DMS:SO4 13 0 25 41 0 0 0 0 0 0 0 11 0 0 0 0 0 10 0 0 229 D H e 48.8 6xbi_A NA EDO:SO4 0 0 37 13 0 6 6 0 0 0 0 0 0 0 6 16 16 0 0 0 230 F H b 0.0 6xbi_A 0 0 0 0 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 43 231 N H e 23.0 6xbi_A K1G CL R1AB_SARS2:3C-like proteinase[305 aa] GOL:DMS 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 232 L H e 54.5 6xbi_A GOL 5 0 0 40 0 0 0 0 7 11 0 8 0 0 8 0 5 16 0 0 233 V H b 12.7 6xbi_A X4P 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11 81 0 234 A H b 0.0 6xbi_A 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 235 M H e 63.8 6xbi_A S7V:R9V R1AB_SARS2:3C-like proteinase[305 aa] DMS 0 0 0 0 0 7 0 0 11 22 33 0 0 6 0 8 0 14 0 0 236 K H e 76.4 6xbi_A CL DMS 17 0 15 0 0 0 6 0 19 0 0 0 0 0 6 16 21 0 0 0 237 Y T e 36.5 6xbi_A QCP:Q8I:X4P GOL 0 0 0 0 0 0 0 0 0 0 0 81 0 0 0 0 0 0 0 19 238 N T e 61.8 6xbi_A T1J:T1M:S7V CL PEG:GOL:DMS 0 0 0 0 0 55 0 0 0 0 8 11 0 16 0 11 0 0 0 0 239 Y B b 9.6 6xbi_A T1J:T1M:S7V:R9V DMS 0 8 0 0 64 0 0 0 0 0 12 0 0 0 0 0 0 0 0 17 240 E b 18.1 6xbi_A T1J:T1M:S7V:QGO:R9V CL R1AB_SARS2:3C-like proteinase[305 aa] DMS:FMT:GOL:MPD:EDO 0 0 0 26 0 0 0 0 0 0 0 0 0 8 0 16 50 0 0 0 241 P e 69.8 6xbi_A T1J:K1G:R9V NA R1AB_SARS2:3C-like proteinase[305 aa] 13 0 0 11 16 0 0 0 0 1 0 0 26 11 0 19 0 0 0 0 242 L b 1.7 6xbi_A NA 0 0 0 0 15 0 0 16 0 23 6 0 0 0 0 0 0 36 0 0 243 T e 39.6 6xbi_A NA R1AB_SARS2:3C-like proteinase[305 aa] PEG:GOL 0 0 0 0 0 16 0 0 17 1 0 6 0 0 0 27 25 6 0 0 244 Q H e 58.2 6xbi_A R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[305 aa] DMS:PEG:EDO 11 0 0 0 0 7 0 0 0 1 0 0 0 11 0 31 31 6 0 0 245 D H e 69.8 6xbi_A QGO R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[298 aa]:3C-like proteinase[305 aa] PEG:GOL 1 0 28 15 1 7 0 1 7 2 0 1 1 16 1 16 1 1 0 1 246 H H b 19.4 6xbi_A QGO CL:NA DMS:FMT:GOL:PEG:EDO 2 0 1 1 1 2 11 1 1 18 1 13 1 1 1 25 16 1 0 1 247 V H b 19.3 6xbi_A DMS 15 0 0 0 0 0 0 5 0 8 0 0 0 0 0 0 17 50 0 0 248 D H e 58.0 6xbi_A R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[298 aa]:3C-like proteinase[305 aa] 2 1 57 8 1 2 1 2 2 3 1 1 2 9 2 2 2 2 0 1 249 I H e 53.8 6xbi_A 6SU:LZE:QGO:GT7 CL R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[298 aa]:3C-like proteinase[305 aa] DMS:EDO 19 18 2 2 1 2 1 12 2 3 16 1 2 1 2 2 2 10 0 1 250 L H b 0.0 6xbi_A 1 0 1 1 29 1 0 21 1 30 0 1 1 1 1 1 1 1 0 7 251 G H e 33.3 6xbi_A 1 0 17 1 1 12 0 1 1 1 0 6 1 9 1 30 16 1 0 1 252 P H e 64.3 6xbi_A 6SU:R6Q:RT2:93J CL DMS:EDO 17 0 1 1 1 1 0 19 16 8 11 1 19 1 1 1 1 1 0 1 253 L H b 1.1 6xbi_A R6Q:RMZ:RT2:93J ACT 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 254 S H b 15.6 6xbi_A DMS:PGE:GOL:EDO 68 0 0 0 0 0 0 0 0 0 0 0 0 0 0 26 0 6 0 0 255 A H e 71.4 6xbi_A RT2 R1AB_SARS2:3C-like proteinase[306 aa] DMS:PG4:PGE:GOL:EDO 68 0 0 0 0 0 10 0 0 0 0 0 0 0 0 16 0 5 0 0 256 Q H e 58.7 6xbi_A R6Q:RMZ:RT2:93J:9JT CL R1AB_SARS2:3C-like proteinase[306 aa] EDO:DMS:PG4:GOL:ACT 0 0 0 0 0 0 0 15 53 0 16 0 0 11 5 0 0 0 0 0 257 T H e 20.1 6xbi_A CL DMS:PG4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 258 G T e 79.8 6xbi_A DMS:PG4:PGE:GOL:EDO 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259 I b 9.4 6xbi_A 0 0 0 0 0 0 0 19 0 0 0 0 0 5 0 0 0 71 0 5 260 A e 39.3 6xbi_A DMS:PGE:GOL:EDO 17 6 13 1 1 1 0 1 1 1 0 1 1 1 1 47 6 1 0 0 261 V H b 9.3 6xbi_A DMS 1 0 1 1 1 1 0 11 1 7 0 1 1 1 1 1 1 70 0 0 262 L H e 33.1 6xbi_A NA:CL FMT:EDO 1 0 1 64 1 7 0 1 1 12 0 1 1 6 1 1 1 1 0 0 263 D H e 36.4 6xbi_A MG:NA:K DMS:IMD:GOL 0 0 26 0 0 0 0 0 11 0 0 0 0 27 26 0 11 0 0 0 264 M H b 0.0 6xbi_A 0 0 0 0 0 0 0 5 0 56 24 0 0 0 0 0 0 15 0 0 265 C H b 0.0 6xbi_A 0 26 0 0 0 0 0 0 0 74 0 0 0 0 0 0 0 0 0 0 266 A H b 3.6 6xbi_A MG:NA DMS:GOL 50 0 5 5 0 0 6 0 15 0 0 0 0 0 0 8 0 0 0 10 267 S H b 1.6 6xbi_A NA:K:MG 51 5 0 0 0 0 0 0 0 15 0 0 0 0 0 29 0 0 0 0 268 L H b 0.0 6xbi_A 0 0 0 0 0 0 0 67 0 33 0 0 0 0 0 0 0 0 0 0 269 K H e 26.9 6xbi_A X4P GOL:DMS 1 0 1 1 0 1 0 1 35 1 0 1 1 29 15 1 1 12 0 0 270 E H e 26.6 6xbi_A CL GOL:DMS:EDO 0 0 0 11 0 0 6 0 6 0 0 0 0 17 27 11 15 8 0 0 271 L H b 6.7 6xbi_A QCP:Q8I:BTB NA DMS:FMT:ACT:EDO 2 1 1 2 1 2 1 16 2 49 1 1 1 1 1 2 7 8 0 1 272 L H b 12.4 6xbi_A QCP:Q8I:BTB PEG:DMS:GOL 0 0 0 0 0 0 12 0 0 58 15 0 0 0 0 0 0 0 0 16 273 Q H e 43.9 6xbi_A QCP:BTB:X4P CL GOL:PEG:IMD:DMS 1 0 1 1 0 7 17 1 12 1 6 25 1 11 1 9 1 8 0 0 274 N H e 60.6 6xbi_A QCP:BTB PEG:IMD:DMS:GOL 13 0 0 6 0 0 0 0 24 0 0 35 0 0 0 13 6 0 0 0 275 G e 42.9 6xbi_A QCP:Q8I:BTB PEG:IMD:DMS:GOL:EDO 1 0 1 1 0 74 0 1 1 1 0 1 1 8 1 8 1 1 0 0 276 M b 10.1 6xbi_A QCP:Q8I R1AB_SARS2:3C-like proteinase nsp5[306 aa] DMS:FMT 8 0 0 0 74 0 0 0 0 0 11 0 0 0 0 0 0 0 7 0 277 N T e 77.0 6xbi_A JGP R1AB_SARS2:3C-like proteinase[306 aa]:3C-like proteinase nsp5[306 aa] DMS 0 8 0 0 0 42 0 0 0 0 0 11 0 39 0 0 0 0 0 0 278 G T e 97.6 6xbi_A JGP R1AB_SARS2:3C-like proteinase[301 aa]:3C-like proteinase nsp5[301 aa] DMS 0 0 0 0 0 92 0 0 0 0 0 0 0 0 0 0 0 0 8 0 279 R e 43.5 6xbi_A JGP R1AB_SARS2:Fusion protein of 3C-like proteinase nsp5 and nsp9.. DMS:SO4:FMT:PO4 0 0 7 0 0 8 0 0 45 0 0 0 0 0 40 0 0 0 0 0 280 T e 47.4 6xbi_A R1AB_SARS2:R1A_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[302 aa]:3C-like proteinase[301 aa]:3C-like proteinase[305 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:3C-like proteinase[300 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[298 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase nsp5[306 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[302 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[283 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:PO4 0 0 0 0 0 0 0 0 0 0 0 6 7 33 0 14 40 0 0 0 281 I B b 0.0 6xbi_A R1AB_SARS2:Fusion protein of 3C-like proteinase nsp5 and nsp9.. 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 282 L T b 19.7 6xbi_A T5D DMS:IPA:FMT:GOL 0 0 0 0 0 0 0 0 0 86 14 0 0 0 0 0 0 0 0 0 283 G T e 86.9 6xbi_A R1AB_SARS2:R1A_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[307 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[300 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1ab[306 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Non-structural protein 7[305 aa] DMS:PO4:IPA:FMT:GOL 0 0 0 0 0 89 0 0 0 0 0 0 0 0 0 11 0 0 0 0 284 S B b 14.1 6xbi_A CL:NA:BR R1AB_SARS2:R1A_SARS2:3C-like proteinase[302 aa]:3C-like proteinase[306 aa]:3C-like proteinase[305 aa]:3C-like proteinase[301 aa]:3C-like proteinase[304 aa]:3C-Like Protease[304 aa]:3C-Like Protease[298 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[301 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp9..:3C-like proteinase nsp5[304 aa]:Replicase polyprotein 1ab[302 aa]:3C-like proteinase nsp5[297 aa] DMS:PO4 0 6 0 0 0 0 6 0 0 0 0 5 0 20 0 40 0 0 0 23 285 A S e 64.3 6xbi_A QCP:Q8I CL:NA:BR R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[307 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[300 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:PO4 5 24 0 0 0 11 0 0 0 0 0 0 0 0 0 23 22 0 0 15 286 L S e 71.9 6xbi_A Q8I CL:NA:BR R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:PO4:EDO:FMT:PEG 0 0 0 0 0 0 0 5 0 5 10 15 0 0 0 48 11 5 0 0 287 L e 21.9 6xbi_A QCP:Q8I CL DMS:EDO:FMT:ACT 0 0 0 0 26 0 0 0 0 74 0 0 0 0 0 0 0 0 0 0 288 E e 28.6 6xbi_A NA:ZN R1AB_SARS2:3C-like proteinase nsp5[306 aa] DMS:PO4:PEG:IPA:1PE 0 23 0 65 0 0 0 0 0 0 0 6 0 0 0 0 6 0 0 0 289 D b 11.1 6xbi_A NA:ZN PEG 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290 E b 9.5 6xbi_A CL:NA:ZN R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:3C-like proteinase nsp5[303 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] PEG 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291 F b 5.3 6xbi_A U1V CL:NA:ZN DMS 0 0 0 0 61 0 8 0 0 31 0 0 0 0 0 0 0 0 0 0 292 T b 13.0 6xbi_A 6SU:QGO:GT7 DMS 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 88 0 0 0 293 P H b 9.3 6xbi_A 6SU:LZE:GT7 CL DMS:EDO 0 0 0 0 0 0 0 6 0 12 0 0 76 0 0 0 6 0 0 0 294 F H e 58.9 6xbi_A 6SU:LZE:GT7 CL R1AB_SARS2:3C-like proteinase[298 aa] EDO:DMS:1PE:PEG 6 0 10 20 11 6 0 0 0 0 0 6 0 0 0 22 11 0 0 8 295 D H b 4.3 6xbi_A JGY:U1V:XZI CL R1AB_SARS2:3C-like proteinase[298 aa] DMS:EDO:1PE 0 0 50 35 0 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 296 V H b 0.0 6xbi_A 93J 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 92 0 0 297 V H e 32.0 6xbi_A 6SU:R6Q:RMZ:RT2:93J:9JT CL EDO:DMS 0 0 0 0 15 8 0 11 0 0 0 16 0 0 0 0 0 35 0 16 298 R H b 7.5 6xbi_A JGY:U1V:LZE:XZI:XZE CL R1AB_SARS2:R1A_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[304 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[301 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:Main Protease[301 aa]:Main Protease[305 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[305 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase nsp5[304 aa]:3C-like proteinase[310 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:IMD:EDO:GOL:1PE:FMT 0 0 0 0 0 0 0 0 18 0 16 15 0 16 35 0 0 0 0 0 299 Q H e 20.4 6xbi_A JGY:U1V:XZI:XZE R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[292 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[306 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] DMS:EDO 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 300 C H e 30.7 6xbi_A RMZ:RT2:93J:9JT:U88 CL R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[306 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:Main Protease[305 aa]:3C-like proteinase[298 aa]:3C protein[306 aa]:COVID-19 MAIN PROTEASE[301 aa]:3C-like proteinase[296 aa]:3C-like proteinase[299 aa]:3C-like proteinase[297 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase[303 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[306 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[295 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] EDO:DMS:GOL:ACT 0 11 0 0 0 0 0 12 0 16 43 0 0 0 0 0 0 18 0 0 301 S H e 60.2 6xbi_A ACE-DTY-LEU-GLN-TYR-ALA-VAL-LEU-ARG-HIS-LYS-ARG-AR..:Nonstructural protein 13/14[10 aa] JGY:RT2:93J:9JT:RK6 R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[301 aa]:3C-like proteinase[303 aa]:3C-like proteinase[306 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[301 aa]:Main Protease[306 aa]:3C protein[306 aa]:3C-like proteinase[298 aa]:3C-like proteinase[299 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[287 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase[310 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[304 aa]:3C-Like Protease[298 aa]:3C-Like Protease[305 aa]:3C-Like Protease[306 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp8..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Replicase polyprotein 1ab[300 aa]:Non-structural protein 11[299 aa]:3C-like proteinase nsp5[293 aa]:Non-structural protein 7[305 aa] EDO:DMS:IPA:GOL:PEG:ACT:PGE 16 0 0 0 6 15 0 0 0 8 16 0 0 0 0 11 0 0 0 29 302 G T e 65.5 6xbi_A Nonstructural protein 13/14[10 aa] XZI:XZE R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[306 aa]:3C-like proteinase[305 aa]:3C-like proteinase[302 aa]:3C-like proteinase[300 aa]:3C-like proteinase[307 aa]:3C-like proteinase[298 aa]:3C-like proteinase[303 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[306 aa]:Main Protease[301 aa]:3C-like proteinase[301 aa]:3C protein[306 aa]:3C-like proteinase[296 aa]:3C-like proteinase[297 aa]:3C-like proteinase[299 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[303 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[306 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp7..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Replicase polyprotein 1ab[283 aa]:Non-structural protein 11[299 aa]:Non-structural protein 7[305 aa] EDO:GOL:DMS:IPA:PEG 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303 V e 48.0 6xbi_A XZE R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[306 aa]:3C-like proteinase[303 aa]:3C-like proteinase[305 aa]:3C-like proteinase[300 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[306 aa]:3C-like proteinase[302 aa]:Main Protease[301 aa]:3C-like proteinase[301 aa]:3C-like proteinase[307 aa]:3C protein[306 aa]:Replicase polyprotein 1ab[303 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[303 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[306 aa]:3C-like proteinase[295 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Non-structural protein 11[299 aa]:Non-structural protein 7[305 aa] EDO:DMS:GOL 0 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 94 0 0 304 T e 76.6 6xbi_A R1AB_SARS2:R1A_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[304 aa]:3C-like proteinase[306 aa]:3C-like proteinase[305 aa]:3C-like proteinase[300 aa]:3C-like proteinase[303 aa]:3C-like proteinase nsp5[304 aa]:Main Protease[304 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[306 aa]:3C-like proteinase[302 aa]:Main Protease[301 aa]:3C-like proteinase[301 aa]:3C-like proteinase[307 aa]:3C protein[306 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[303 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[306 aa]:Replicase polyprotein 1a[299 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Fusion protein of 3C-like proteinase nsp5 and nsp9..:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Non-structural protein 7[305 aa] EDO:DMS:GOL 0 0 0 0 0 0 0 0 24 0 0 29 0 0 15 0 17 16 0 0 305 F b 16.7 6xbi_A R1AB_SARS2:nsp6/7 peptidyl substrate[10 aa] S1U:S1L:S5L R1A_SARS2:R1AB_SARS2:A0A7U3EDN3_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[305 aa]:3C-like proteinase[304 aa]:3C-like proteinase[300 aa]:3C-like proteinase[303 aa]:3C-like proteinase nsp5[305 aa]:Main Protease[306 aa]:3C-like proteinase[302 aa]:Main Protease[301 aa]:3C-like proteinase[301 aa]:3C-like proteinase[307 aa]:3C protein[306 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[303 aa]:3C-like proteinase nsp5[304 aa]:Replicase polyprotein 1ab[305 aa]:Replicase polyprotein 1a[306 aa]:3C-Like Protease[306 aa]:Replicase polyprotein 1ab[306 aa]:ORF1a polyprotein[305 aa]:3C-like proteinase nsp5[297 aa]:Replicase polyprotein 1ab[302 aa]:Replicase polyprotein 1ab[299 aa]:Non-structural protein 7[305 aa] EDO:DMS 0 0 0 0 11 0 0 0 0 74 16 0 0 0 0 0 0 0 0 0 306 Q e 92.9 6xbi_A NA R1AB_SARS2:R1A_SARS2:3C-like proteinase[306 aa]:3C-like proteinase[304 aa]:3C-like proteinase[305 aa]:3C protein[306 aa]:3C-like proteinase[301 aa]:3C-like proteinase[302 aa]:3C-like proteinase nsp5[306 aa]:3C-like proteinase nsp5[301 aa]:3C-like proteinase nsp5[300 aa]:3C-like proteinase nsp5[302 aa]:3C-like proteinase nsp5[304 aa]:3C-like proteinase[303 aa]:Replicase polyprotein 1a[306 aa]:Replicase polyprotein 1ab[306 aa]:3C-like proteinase nsp5[303 aa]:Replicase polyprotein 1ab[302 aa] DMS 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0