site aa pred_sec pred_expbur pred_accessibility pdb_asym_id hetero nucleotide compound metal otherpoly homo precipitant A C D E F G H I K L M N P Q R S T V W Y feature_table variant 1 M 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 DISORDER:predicted by DISOPRED 2 A 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0 DISORDER:predicted by DISOPRED 3 A 66 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 DISORDER:predicted by DISOPRED 4 G 0 0 0 0 0 80 0 0 0 0 0 0 0 0 0 0 0 20 0 0 DISORDER:predicted by DISOPRED 5 G 0 0 14 0 0 52 0 0 0 0 0 0 20 0 0 0 0 15 0 0 DISORDER:predicted by DISOPRED 6 P 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 14 0 20 0 0 DISORDER:predicted by DISOPRED 7 G 26 0 0 0 0 43 0 0 0 0 0 0 0 0 31 0 0 0 0 0 DISORDER:predicted by DISOPRED 8 A 53 26 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21 0 0 DISORDER:predicted by DISOPRED 9 G 0 0 0 10 0 90 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DISORDER:predicted by DISOPRED 10 S 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 DISORDER:predicted by DISOPRED 11 A 53 0 0 0 0 10 0 0 0 0 0 0 0 0 0 26 0 10 0 0 DISORDER:predicted by DISOPRED 12 A 18 0 0 0 0 0 0 0 0 37 0 0 24 0 0 21 0 0 0 0 DISORDER:predicted by DISOPRED 13 P 0 0 13 14 0 13 0 0 0 10 0 0 39 0 0 0 0 10 0 0 DISORDER:predicted by DISOPRED 14 V 11 0 21 0 0 0 0 0 0 0 0 0 14 0 0 26 10 18 0 0 DISORDER:predicted by DISOPRED 15 S 21 0 0 0 0 0 0 11 0 0 0 0 8 0 0 33 15 11 0 0 DISORDER:predicted by DISOPRED 16 S 0 0 49 0 9 0 0 0 0 0 0 0 0 0 0 33 0 0 0 9 DISORDER:predicted by DISOPRED 17 T 0 0 0 0 0 0 0 0 0 45 39 0 0 0 0 0 16 0 0 0 18 S 0 0 0 0 17 0 12 0 0 0 0 22 0 0 0 48 0 0 0 0 19 S e 97.7 6i3n_M 10 0 0 0 0 0 0 0 0 0 0 16 0 0 10 65 0 0 0 0 20 L b 16.9 6i3n_M 0 0 0 0 0 0 0 50 0 32 0 0 0 0 0 0 0 19 0 0 21 P e 48.8 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 22 L G b 1.1 6i3n_M 0 0 0 0 0 0 0 0 0 81 9 0 0 0 0 0 0 10 0 0 23 A G e 50.0 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 25 0 0 0 0 0 0 0 0 10 0 0 0 0 16 0 10 40 0 0 24 A G b 7.1 6i3n_M 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 L S b 3.4 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 26 N e 41.2 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 27 M H e 58.0 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 10 0 0 0 0 0 16 0 0 21 0 0 0 0 0 0 26 0 26 28 R H e 52.6 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 32 0 0 0 0 0 24 0 0 25 10 9 0 0 0 29 V H b 0.0 6i3n_M 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 81 0 0 30 R H b 10.7 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 31 R H e 66.8 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 24 0 35 0 0 0 0 0 41 0 0 0 0 0 32 R H e 32.8 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 19 0 0 0 0 0 81 0 0 0 0 0 33 L H b 2.8 6i3n_M 0 0 0 0 0 0 0 0 0 90 0 0 0 0 0 0 0 10 0 0 34 S H b 5.5 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:Myeloid differentiation primary response protein M.. 0 9 0 0 0 45 0 0 0 0 0 0 0 0 0 46 0 0 0 0 S->Y:US:rs1319438: -; 35 L H e 56.2 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 36 F H b 17.2 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36 37 L H b 0.6 6i3n_M 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 38 N T e 31.5 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 39 V S e 62.0 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 25 0 0 V->M:US:rs7703876: -; 40 R e 53.4 6i3n_M MYD88_HUMAN:Myeloid differentiation primary response protein M.. 0 0 9 0 0 0 0 0 0 0 0 8 0 0 73 0 10 0 0 0 41 T e 35.7 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 33 0 0 0 0 0 0 0 0 0 0 35 0 0 0 0 31 0 0 0 42 Q S e 94.4 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 19 0 0 0 0 0 0 0 0 0 0 0 13 18 0 0 32 17 0 0 43 V S e 92.0 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 84 0 0 44 A S e 55.4 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 A b 19.6 6i3n_M 84 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 0 0 46 D b 3.1 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 92 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 W H b 1.6 6i3n_M 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 48 T H b 19.5 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 0 0 26 0 0 0 10 0 65 0 0 0 49 A H b 19.6 6i3n_M MYD88_HUMAN:Myeloid differentiation primary response protein M.. 31 0 0 0 0 6 0 0 0 6 0 0 0 8 9 23 10 7 0 0 50 L H b 2.2 6i3n_M 0 0 0 0 0 0 0 0 0 74 0 0 0 0 0 0 0 26 0 0 51 A H b 0.0 6i3n_M 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 52 E H e 65.3 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53 E H e 34.2 6i3n_M 16 0 0 48 0 0 0 0 9 10 0 16 0 0 0 0 0 0 0 0 54 M T b 1.9 6i3n_M 0 0 0 0 0 0 0 0 0 19 81 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 55 D T e 79.6 6i3n_M MYD88_HUMAN:Myeloid differentiation primary response protein M.. 0 0 28 0 0 65 0 0 0 0 0 6 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 56 F b 12.0 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 74 0 9 0 0 0 0 0 0 0 0 0 0 0 0 17 DOMAIN:/note="Death":DOMAIN:/note="Death" 57 E e 57.3 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 26 38 0 0 0 0 0 0 0 0 0 0 0 16 19 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 58 Y H e 65.2 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90 DOMAIN:/note="Death":DOMAIN:/note="Death" 59 L H e 61.2 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 60 E H e 45.7 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 61 I H b 8.8 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 62 R H e 50.6 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 44 0 0 0 0 7 49 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 63 Q H e 51.0 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 13 0 0 0 0 0 0 0 53 0 19 16 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 64 L H b 5.1 6i3n_M MYD88_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 34 0 0 0 0 41 0 0 0 0 0 0 0 0 0 26 DOMAIN:/note="Death":DOMAIN:/note="Death" 65 E T e 22.1 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 91 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 66 T T e 71.4 6i3n_M 9 0 16 0 0 0 0 0 17 0 0 0 0 0 17 10 31 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 67 Q S e 36.7 6i3n_M MYD88_HUMAN:Myeloid differentiation primary response protein M.. 10 16 0 0 8 0 12 0 0 9 0 0 0 6 23 0 0 0 0 16 DOMAIN:/note="Death":DOMAIN:/note="Death" 68 A S e 79.5 6i3n_M 19 0 10 0 0 0 0 10 0 8 0 0 46 9 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 69 D e 34.0 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 10 81 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 70 P H b 12.4 6i3n_M 0 8 0 0 0 0 0 0 0 0 0 0 83 0 0 9 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 71 T H b 1.3 6i3n_M 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 90 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 72 G H b 0.0 6i3n_M 9 0 0 10 0 12 0 0 0 0 17 0 0 0 36 7 0 10 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 73 R H e 34.0 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 9 0 0 0 0 0 0 0 45 0 0 0 0 0 26 19 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 74 L H b 0.0 6i3n_M 0 0 0 0 0 0 0 16 0 65 0 0 0 0 0 0 0 19 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 75 L H b 1.1 6i3n_M 0 0 0 0 0 0 0 0 0 91 0 0 0 0 0 0 0 0 0 9 DOMAIN:/note="Death":DOMAIN:/note="Death" 76 D H e 41.4 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 38 44 0 0 0 0 0 0 0 0 0 0 9 0 10 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 77 A H e 40.2 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 25 0 57 9 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 78 W T b 3.2 6i3n_M 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 91 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 79 Q S e 35.7 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 27 0 0 0 0 9 0 0 0 0 65 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 80 G S e 85.7 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 17 0 0 0 0 31 0 0 17 0 0 0 9 0 7 9 10 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 81 R S e 33.6 6i3n_M MYD88_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 17 9 0 0 0 0 74 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 82 P T e 105.4 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 17 0 0 0 9 0 0 0 0 0 0 42 0 0 31 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 83 G T e 46.4 6i3n_M 0 0 19 0 0 55 0 0 0 0 0 0 0 0 26 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 84 A e 20.5 6i3n_M 93 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 85 S b 13.3 6i3n_M 0 0 0 0 0 0 0 0 8 0 0 0 0 9 0 38 46 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 86 V H b 6.0 6i3n_M 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 87 G H e 39.3 6i3n_M 10 0 0 0 0 90 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 88 R H e 28.5 6i3n_M 0 0 0 0 0 17 0 0 26 0 0 10 0 9 38 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 89 L H b 1.7 6i3n_M 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 90 L H e 29.8 6i3n_M 0 0 0 0 0 0 0 0 0 91 0 0 0 0 0 0 0 9 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 91 E H e 57.8 6i3n_M 0 0 0 65 0 0 0 0 0 0 0 0 0 0 0 35 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 92 L H b 0.6 6i3n_M 0 0 0 0 0 0 0 35 0 47 17 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 93 L H b 1.7 6i3n_M 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" L->P:LP/P:rs1378530: Immunodeficiency 68 (IMD68) ; 94 T H e 46.8 6i3n_M 26 0 16 10 0 0 0 0 17 0 0 0 0 0 9 10 12 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 95 K H e 63.2 6i3n_M 0 0 0 10 0 0 0 0 52 13 0 16 0 9 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 96 L T e 20.8 6i3n_M 10 0 0 0 0 0 0 0 0 47 17 0 0 0 0 0 0 26 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 97 G T e 57.1 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 21 36 0 34 0 0 0 0 0 0 0 0 0 0 9 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 98 R b 17.0 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" R->C:US:rs199396: -; 99 D e 59.3 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. 0 0 25 13 0 0 9 0 26 0 0 27 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 100 D H e 53.1 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 101 V H b 1.3 6i3n_M 0 0 0 0 0 0 0 30 0 0 0 0 0 0 0 0 0 70 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 102 L H e 29.8 6i3n_M 0 0 0 0 0 0 0 10 0 74 0 0 0 0 0 0 0 16 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 103 L H e 84.3 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. 0 0 0 26 0 0 0 0 6 21 7 0 0 0 0 10 17 6 0 7 DOMAIN:/note="Death":DOMAIN:/note="Death" 104 E H e 42.7 6i3n_M IRAK4_HUMAN:Interleukin-1 receptor-associated kinase 4[107 aa].. MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 43 57 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 105 L S b 1.1 6i3n_M 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 106 G H e 31.0 6i3n_M 0 0 0 0 0 52 0 0 23 0 0 0 0 10 16 0 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 107 P H e 66.7 6i3n_M 0 0 14 10 0 9 0 0 0 0 0 0 52 0 0 6 0 9 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 108 S H b 18.8 6i3n_M 0 0 0 0 0 0 0 10 0 33 10 0 0 0 13 34 0 0 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 109 I H b 4.7 6i3n_M 0 0 0 0 0 0 0 81 0 10 0 0 0 0 0 0 0 9 0 0 DOMAIN:/note="Death":DOMAIN:/note="Death" 110 E H e 67.8 6i3n_M 0 0 19 81 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111 E H e 49.7 6i3n_M 17 0 10 73 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112 D H b 4.3 6i3n_M MYD88_HUMAN:Myeloid differentiation primary response protein M.. 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113 C H b 16.7 6i3n_M 0 90 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 114 Q H e 55.6 6i3n_M 0 0 0 0 0 0 0 0 12 0 13 0 0 24 51 0 0 0 0 0 115 K H e 50.9 6i3n_M MYD88_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 0 0 55 0 0 0 0 27 18 0 0 0 0 0 116 Y H e 27.4 6i3n_M MYD88_HUMAN:H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 27 0 0 67 117 I H e 38.6 6i3n_M 1 7 0 0 0 0 0 36 0 45 7 0 0 0 0 0 0 0 0 0 118 L H e 69.1 6i3n_M 2 0 1 19 1 6 0 1 1 55 0 1 1 1 6 1 1 1 0 1 119 K H e 85.8 6i3n_M H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 1 0 1 8 0 1 0 1 52 1 0 6 1 1 25 1 1 1 0 0 120 Q H e 66.8 6i3n_M H0Y4G9_HUMAN:Myeloid differentiation primary response protein M.. 1 0 1 1 0 1 0 1 28 1 0 1 1 47 14 1 1 1 0 0 121 Q e 59.7 6i3n_M 0 0 0 13 0 0 0 0 7 7 0 11 27 35 0 0 0 0 0 0 122 Q 1 0 1 1 0 1 0 1 45 1 0 12 1 26 7 1 1 1 0 0 123 E 1 0 1 20 1 1 0 1 41 2 0 1 1 17 8 1 1 1 0 1 124 E 12 0 8 27 1 1 7 1 1 2 0 7 1 1 28 1 1 1 0 1 125 A 28 0 1 1 1 1 0 1 1 2 0 1 35 1 1 17 1 7 0 1 126 E 1 0 0 54 0 0 0 0 0 1 0 27 13 0 0 0 0 0 0 0 127 K 0 0 0 0 0 0 0 0 35 13 0 0 18 7 0 27 0 0 0 0 128 P 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 129 L 2 1 1 2 1 2 1 8 2 56 1 1 1 1 1 2 2 14 0 1 130 Q 0 0 0 27 0 0 0 0 0 0 0 0 0 73 0 0 0 0 0 0 131 V 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 27 0 60 0 0 132 A 19 0 23 0 0 0 0 0 0 0 0 7 24 0 0 0 27 0 0 0 133 A 15 0 0 11 0 0 0 0 13 0 0 0 0 7 10 37 0 6 0 0 134 V 0 0 0 0 0 0 0 5 0 0 0 0 0 0 0 27 0 68 0 0 135 D 0 0 90 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136 S 27 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73 0 0 0 0 S->G:US:-: -;S->I:US:-: -; 137 S 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 138 V 1 0 1 1 7 7 0 11 1 1 0 1 1 28 1 1 1 38 0 0 139 P 1 0 1 1 0 1 7 1 1 1 0 1 76 1 1 1 6 1 0 0 140 R 1 0 1 1 0 1 0 1 13 1 0 1 1 11 34 1 28 1 5 0 141 T 1 0 1 1 1 1 0 6 1 2 0 1 1 1 1 28 51 1 0 1 142 A 10 0 1 1 1 1 0 1 11 8 0 6 7 40 1 8 1 1 0 1 143 E 0 0 33 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144 L 0 0 0 0 0 0 0 0 0 53 10 0 0 13 25 0 0 0 0 0 145 A 14 0 0 6 0 10 0 0 0 0 7 0 0 11 0 32 0 7 0 13 146 G T e 29.8 2js7_A 0 0 0 0 0 60 0 0 0 0 0 0 0 0 13 27 0 0 0 0 147 I T e 97.1 2js7_A 0 0 0 0 0 0 0 66 0 7 0 0 0 0 0 0 0 27 0 0 148 T e 69.5 2js7_A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 149 T T e 93.5 2js7_A 0 0 0 0 0 0 0 8 9 18 0 0 0 0 0 23 42 0 0 0 150 L T e 111.8 2js7_A 0 0 0 9 0 0 5 0 0 15 22 0 23 0 13 9 0 0 0 5 151 D e 30.2 2js7_A 0 0 56 0 0 0 0 0 0 0 0 0 0 0 0 44 0 0 0 0 152 D e 30.2 2js7_A 0 0 56 0 0 0 0 0 0 23 0 0 0 0 0 0 0 22 0 0 153 P T e 69.0 2js7_A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 154 L T e 30.9 2js7_A 0 0 0 14 0 0 0 0 0 22 0 0 23 5 0 5 0 22 0 10 155 G S e 67.9 2js7_A 0 0 0 0 0 73 0 0 0 16 0 0 0 0 0 0 11 0 0 0 156 H e 67.5 2js7_A 0 0 0 0 0 8 22 0 0 4 0 0 0 12 44 8 0 0 0 0 157 M b 12.6 2js7_A 11 0 0 0 0 21 16 7 3 4 13 0 0 0 0 0 14 0 11 0 158 P T e 90.7 2js7_A 0 0 0 14 0 0 0 0 0 0 0 0 63 0 0 20 4 0 0 0 159 E T e 43.2 2js7_A 0 0 8 31 0 0 11 0 30 0 0 10 0 10 0 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 160 R e 70.4 2js7_A 0 2 8 11 0 0 2 0 10 12 3 0 0 0 14 8 18 11 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 161 F E b 3.3 2js7_A 0 0 0 0 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 162 D E b 0.0 2js7_A 0 0 93 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 163 A E b 0.0 2js7_A 83 0 0 0 0 0 0 5 0 0 0 0 0 0 0 0 0 12 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 164 F E b 0.5 2js7_A 0 12 0 0 76 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 165 I E b 0.0 2js7_A 0 0 0 0 0 0 0 37 0 0 0 0 0 0 0 0 0 63 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 166 C E b 0.0 2js7_A 0 32 0 0 0 0 0 9 0 0 0 0 0 0 0 59 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 167 Y b 0.4 2js7_A 0 0 0 0 4 0 12 0 0 0 0 0 0 0 0 0 0 0 0 84 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 168 C b 0.0 2js7_A 10 35 0 0 0 0 0 0 0 7 0 0 0 0 0 48 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 169 P G e 56.6 2js7_A 15 0 5 27 0 0 4 0 7 0 0 0 16 9 5 12 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 170 S G e 64.1 2js7_A 7 0 0 31 0 0 2 0 10 0 0 8 0 17 9 12 4 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 171 D G b 7.4 2js7_A 0 0 85 12 0 0 0 0 0 0 0 3 0 0 0 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 172 I H e 22.2 2js7_A 2 0 0 22 5 0 4 13 0 14 0 0 0 4 12 14 7 0 0 4 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 173 Q H e 65.3 2js7_A 4 0 12 16 0 0 2 0 8 4 0 2 0 12 0 15 7 6 0 12 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 174 F H e 37.8 2js7_A 12 0 0 0 53 0 7 0 0 0 0 0 0 0 0 0 0 0 28 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 175 V H b 0.0 2js7_A 26 0 0 0 0 0 0 4 0 5 0 0 0 0 0 0 0 65 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 176 Q H b 19.9 2js7_A 0 0 0 23 0 0 11 0 4 5 0 14 0 25 9 0 0 7 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 177 E H e 23.1 2js7_A 0 0 15 50 8 0 0 0 0 5 0 15 0 0 0 0 7 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 178 M H b 0.0 2js7_A 0 0 0 0 0 0 0 19 0 34 39 0 0 0 0 0 9 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" M->I:US:rs4128511: -; 179 I H b 6.4 2js7_A 4 0 0 0 0 0 0 18 0 27 5 0 0 0 0 0 0 44 0 0 MUTAGEN:/note="I->N: In Pococurante (Poc); abolished MYD88- dependent sensing of most Toll-like receptor (TLR) ligands.":DOMAIN:/note="TIR":MUTAGEN:/note="I->N: In Pococurante (Poc); abolished MYD88- dependent sensing of most Toll-like receptor (TLR) ligands.":DOMAIN:/note="TIR" 180 R H e 57.7 2js7_A 0 0 7 0 0 0 0 0 23 0 0 0 19 17 18 15 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 181 Q H e 29.6 2js7_A 4 0 0 11 0 5 0 0 2 0 4 14 8 24 11 7 0 0 0 12 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 182 L H b 0.6 2js7_A 0 0 0 0 0 0 0 0 0 68 0 0 0 8 0 0 0 24 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 183 E H e 32.7 2js7_A 0 0 0 80 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 184 Q T e 64.8 2js7_A 0 0 0 30 0 12 15 0 0 0 4 5 0 23 5 7 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 185 T S e 44.2 2js7_A 2 0 0 5 10 17 0 0 7 0 0 5 0 0 15 19 20 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 186 N S b 18.2 2js7_A 0 2 14 13 0 12 4 0 0 0 0 14 4 14 8 0 6 9 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 187 Y S e 51.3 2js7_A 12 0 0 0 23 0 7 0 0 0 0 0 24 4 8 0 5 0 0 13 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 188 R e 89.3 2js7_A 1 0 0 0 0 20 0 0 15 1 0 7 20 0 15 12 7 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 189 L b 6.2 2js7_A 1 0 0 0 33 1 0 0 0 37 0 0 0 0 0 1 0 0 0 24 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 190 K b 18.9 2js7_A 0 0 0 0 0 0 3 0 66 0 0 0 0 10 14 0 7 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 191 L b 3.4 2js7_A 0 19 0 0 0 0 0 0 0 81 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 192 C E b 0.0 2js7_A 0 81 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 193 V E b 0.0 2js7_A 0 0 0 0 12 0 0 12 0 51 0 0 0 0 0 0 0 24 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 194 S S e 23.4 2js7_A 7 0 4 4 24 0 41 0 0 0 0 0 0 12 0 8 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 195 D e 23.5 2js7_A 0 0 33 19 0 0 0 0 15 12 0 5 0 8 0 0 0 0 0 9 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 196 R e 36.0 2js7_A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 MUTAGEN:/note="R->A: Reduced interaction with TIRAP, and strongly reduced activity. Strongly reduced interaction with TIRAP; when associated with A-288.":DOMAIN:/note="TIR":MUTAGEN:/note="R->A: Reduced interaction with TIRAP, and strongly reduced activity. Strongly reduced interaction with TIRAP; when associated with A-288.":DOMAIN:/note="TIR" R->C:LP/P:rs1378530: Immunodeficiency 68 (IMD68) ; 197 D S e 89.5 2js7_A 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 MUTAGEN:/note="D->A: Slightly reduced activity.":DOMAIN:/note="TIR":MUTAGEN:/note="D->A: Slightly reduced activity.":DOMAIN:/note="TIR" 198 V S e 56.0 2js7_A 13 0 0 0 44 0 0 0 0 8 0 0 0 0 0 5 0 26 4 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 199 L S b 10.7 2js7_A 6 0 0 4 0 0 0 21 0 48 0 0 0 0 0 0 6 15 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 200 P S e 39.5 2js7_A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 201 G S e 89.3 2js7_A 0 0 0 8 0 85 0 0 0 0 0 0 0 0 8 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 202 T b 12.3 2js7_A 8 0 0 8 0 24 0 4 16 0 0 4 0 0 0 5 19 9 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 203 C S e 47.3 2js7_A 21 28 5 1 1 2 0 14 1 2 0 1 1 1 1 2 1 1 16 1 MUTAGEN:/note="C->S: Abolished interaction with E.coli TcpC without affecting ability to promote Toll-like receptor (TLR)- mediated cytokine production; when associated with S-280.":DOMAIN:/note="TIR":MUTAGEN:/note="C->S: Abolished interaction with E.coli TcpC without affecting ability to promote Toll-like receptor (TLR)- mediated cytokine production; when associated with S-280.":DOMAIN:/note="TIR" 204 V b 16.0 2js7_A 2 0 1 1 1 2 0 32 1 6 5 1 1 1 1 2 9 34 0 1 DOMAIN:/note="TIR":DOMAIN:/note="TIR" V->F:US:rs7769954: -; 205 W b 17.5 2js7_A 1 0 1 1 10 1 0 14 1 1 0 1 1 4 5 9 6 22 20 1 DOMAIN:/note="TIR":DOMAIN:/note="TIR" W->R:US:-: -; 206 S b 7.0 2js7_A 12 0 36 15 0 0 0 0 0 0 0 0 0 0 0 29 7 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" S->C:US:-: -; 207 I b 7.6 2js7_A 0 0 0 12 0 0 0 37 0 12 0 20 8 0 0 0 0 12 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" I->T:US:-: -; 208 A b 4.5 2js7_A 27 12 4 0 0 0 0 27 0 0 0 0 0 0 0 10 14 7 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 209 S G e 58.6 2js7_A 16 0 4 0 0 2 7 15 0 5 0 0 0 16 0 22 0 12 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" S->R:US:-: -; 210 E G e 75.4 2js7_A 12 0 30 20 0 0 0 0 0 0 0 18 0 0 0 20 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 211 L G e 44.9 2js7_A 12 0 0 0 5 1 0 14 0 47 0 0 0 0 0 16 0 1 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 212 I H b 2.3 2js7_A 1 0 0 0 0 1 0 69 0 8 0 0 0 0 0 12 5 1 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 213 E H e 25.6 2js7_A 1 0 0 43 0 1 10 0 0 1 0 9 0 12 6 6 0 8 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 214 K H e 49.1 2js7_A 1 8 0 9 0 1 2 0 43 1 0 14 0 0 2 12 5 1 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 215 R H e 35.6 2js7_A 2 0 1 1 1 2 12 1 10 2 0 6 1 1 29 27 1 1 0 1 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 216 C E b 0.7 2js7_A 3 40 2 2 1 2 1 2 2 3 1 1 2 1 2 30 2 2 0 1 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 217 R E e 41.1 2js7_A 0 0 0 0 0 0 11 0 14 0 0 0 0 0 75 0 0 0 0 0 MUTAGEN:/note="R->A: Strongly reduced activity.":DOMAIN:/note="TIR":MUTAGEN:/note="R->A: Strongly reduced activity.":DOMAIN:/note="TIR" 218 R E b 0.0 2js7_A 1 0 1 1 0 1 0 1 37 1 0 8 1 0 45 1 1 1 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 219 M E b 0.0 2js7_A 1 0 1 1 0 1 0 1 1 21 20 1 1 0 1 1 33 17 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" M->T:US:-: -; 220 V E b 0.0 2js7_A 6 0 0 0 0 0 0 52 0 13 0 0 0 0 0 0 0 29 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 221 V E b 0.0 2js7_A 0 9 0 0 15 0 0 12 0 19 4 0 0 0 0 0 0 42 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 222 V E b 0.0 2js7_A 0 0 0 0 0 0 0 4 0 12 0 0 0 0 0 0 0 85 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 223 V b 0.0 2js7_A 0 0 0 0 0 0 0 36 0 39 0 0 0 0 0 0 0 25 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 224 S b 0.0 2js7_A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88 12 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 225 D H e 29.0 2js7_A 0 0 28 19 0 0 0 0 4 0 0 4 24 12 5 5 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 226 D H b 16.0 2js7_A 15 0 14 6 0 12 15 0 0 0 0 29 0 0 0 9 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 227 Y H b 0.0 2js7_A 0 0 0 0 51 0 0 0 0 0 0 0 0 0 0 7 0 0 0 41 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 228 L H b 17.4 2js7_A 0 0 0 0 0 0 0 17 0 64 4 0 0 0 0 0 0 15 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 229 Q H e 65.8 2js7_A 0 0 11 2 0 0 4 0 15 0 0 5 0 37 12 8 4 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 230 S S b 18.0 2js7_A 0 0 12 0 0 5 0 0 0 0 0 4 0 0 8 72 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" S->N:US:rs1353791: -; 231 K H e 77.4 2js7_A 4 0 7 37 0 0 0 0 8 0 0 5 15 0 9 4 6 0 0 5 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 232 E H b 15.1 2js7_A 7 0 2 17 0 0 0 0 0 0 0 0 0 6 0 0 0 0 68 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 233 C H b 5.3 2js7_A 10 77 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 5 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 234 D H e 54.3 2js7_A 0 0 21 0 0 0 0 9 34 6 5 0 0 0 17 7 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 235 F H b 15.8 2js7_A 0 0 0 0 41 0 7 0 0 15 0 0 0 0 0 0 0 0 0 37 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 236 Q H b 0.0 2js7_A 0 0 0 60 0 0 0 0 0 0 0 0 0 33 0 7 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 237 T H b 18.2 2js7_A 0 0 0 0 16 0 0 0 0 23 20 0 0 0 0 0 22 5 0 10 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 238 K H e 64.2 2js7_A 0 0 16 10 0 0 0 0 32 20 0 0 0 5 12 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 239 F H b 5.3 2js7_A 12 0 0 8 38 0 0 10 0 6 8 0 0 12 0 4 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 240 A H b 0.0 2js7_A 65 0 0 0 0 14 0 0 0 1 0 0 0 0 0 16 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 241 L H e 75.8 2js7_A 0 0 0 0 4 0 20 0 0 48 0 0 0 10 0 6 0 8 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 242 S H e 67.2 2js7_A 1 0 8 18 2 1 0 0 0 1 6 0 0 5 10 22 24 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 243 L H b 19.7 2js7_A 0 0 8 12 0 0 0 0 6 34 0 18 0 0 2 10 0 0 12 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 244 S e 41.4 2js7_A 17 6 0 7 5 4 0 0 0 2 13 9 0 12 0 22 0 4 0 0 MOD_RES:/note="Phosphoserine":DOMAIN:/note="TIR":MOD_RES:/note="Phosphoserine":DOMAIN:/note="TIR" 245 P T e 92.2 2js7_A 7 0 15 0 20 0 8 0 0 10 0 0 34 0 0 7 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 246 G T e 54.8 2js7_A 11 0 3 5 0 35 0 0 0 12 0 6 0 8 5 7 0 0 0 6 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 247 A H e 47.3 2js7_A 41 0 4 14 0 0 0 0 0 7 0 5 0 7 8 12 0 3 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 248 H H b 4.2 2js7_A 0 0 0 0 0 13 19 11 0 1 0 15 0 3 18 18 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 249 Q H b 18.4 2js7_A 0 0 5 23 0 0 3 0 6 13 0 19 0 9 18 4 2 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 250 K H e 41.5 2js7_A 15 0 8 0 0 12 0 16 22 0 0 0 0 0 4 12 0 12 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 251 R T b 11.9 2js7_A 5 19 0 0 0 14 0 0 0 11 0 7 0 0 32 0 0 6 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 252 L E b 0.0 2js7_A 0 0 0 0 0 0 0 28 0 52 0 0 0 0 0 0 12 9 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" L->P:US:rs3879072: Macroglobulinemia, Waldenstrom, 1 (WM1) ; 253 I E b 11.1 2js7_A 0 0 0 11 0 0 0 70 0 5 0 0 0 0 0 0 0 15 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 254 P E b 0.0 2js7_A 0 0 0 7 12 0 0 0 0 13 0 0 59 0 0 0 0 10 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 255 I E b 0.0 2js7_A 0 0 0 0 0 0 0 52 0 12 0 0 0 0 7 0 0 30 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 256 K E b 11.8 2js7_A 0 0 7 8 0 0 0 5 27 19 0 0 0 10 0 6 0 18 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 257 Y S b 3.9 2js7_A 0 2 0 0 0 0 0 7 13 24 0 0 0 0 2 14 0 0 0 38 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 258 K S e 25.0 2js7_A 0 0 0 9 0 24 9 0 52 0 0 0 0 5 2 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 259 A e 68.8 2js7_A 30 0 0 4 0 8 0 7 14 12 0 0 5 0 6 12 2 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 260 M e 21.7 2js7_A 0 0 0 0 0 0 0 23 0 17 22 0 0 0 0 12 0 27 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 261 K e 97.2 2js7_A 0 0 5 9 0 0 0 0 35 10 0 0 17 4 17 2 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 262 K e 45.8 2js7_A 12 0 8 5 0 0 0 7 46 0 0 2 0 15 6 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 263 E e 91.5 2js7_A 12 0 11 37 0 0 0 0 0 1 0 0 12 3 18 4 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 264 F e 42.6 2js7_A 0 0 0 0 46 0 0 0 0 39 0 0 0 3 0 0 0 0 0 12 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 265 P e 25.6 2js7_A 0 17 4 0 0 0 0 6 12 0 0 0 41 0 0 0 7 6 0 5 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 266 S T e 69.5 2js7_A 5 0 0 6 0 0 0 0 17 0 0 6 31 0 13 22 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 267 I T b 12.3 2js7_A 7 0 4 12 0 0 0 22 6 29 0 0 8 0 0 0 0 7 0 5 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 268 L T b 0.0 2js7_A 0 0 0 0 0 0 0 0 7 56 0 0 0 6 17 0 7 0 0 6 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 269 R S e 76.7 2js7_A 0 0 7 0 0 0 0 0 23 0 0 3 0 0 52 3 13 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 270 F e 21.1 2js7_A 0 0 0 0 46 0 0 17 0 11 5 0 8 0 5 0 0 7 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 271 I S e 39.2 2js7_A 0 0 0 0 0 0 0 22 0 31 31 12 0 0 0 0 0 0 0 5 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 272 T S e 48.1 2js7_A 0 0 0 0 0 0 0 0 0 5 0 19 0 0 0 7 58 0 0 12 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 273 V e 34.0 2js7_A 0 0 0 0 0 0 0 8 6 4 0 0 0 0 7 0 20 22 7 26 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 274 C E b 7.3 2js7_A 0 25 0 0 0 0 0 9 18 13 0 7 7 0 2 0 6 13 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 275 D E b 8.6 2js7_A 0 0 45 7 0 0 0 0 16 0 0 6 0 0 0 0 27 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 276 Y T e 22.2 2js7_A 0 0 0 0 0 11 0 0 0 0 0 0 0 0 0 7 6 0 22 53 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 277 T T e 33.8 2js7_A 0 0 0 7 0 6 0 0 9 17 2 0 2 0 11 2 29 7 0 6 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 278 N e 52.1 2js7_A 0 0 34 0 0 21 7 0 2 6 0 24 0 0 6 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 279 P T e 72.1 2js7_A MG 4 0 3 28 0 1 0 0 0 1 0 0 47 6 0 7 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 280 C T e 85.3 2js7_A 8 27 1 5 1 6 0 1 11 9 0 1 1 1 1 1 8 8 7 3 MUTAGEN:/note="C->S: Abolished interaction with E.coli TcpC without affecting ability to promote Toll-like receptor (TLR)- mediated cytokine production; when associated with S-203.":DOMAIN:/note="TIR":MUTAGEN:/note="C->S: Abolished interaction with E.coli TcpC without affecting ability to promote Toll-like receptor (TLR)- mediated cytokine production; when associated with S-203.":DOMAIN:/note="TIR" 281 T T b 12.3 2js7_A 1 0 0 0 0 15 3 0 0 8 0 0 0 29 0 11 30 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" T->P:US:-: -; 282 K e 44.8 2js7_A MG 1 0 7 0 0 1 0 0 29 1 0 0 0 38 20 1 0 0 0 0 MUTAGEN:/note="K->A: Slightly reduced activity.":DOMAIN:/note="TIR":MUTAGEN:/note="K->A: Slightly reduced activity.":DOMAIN:/note="TIR" 283 S S e 84.4 2js7_A 6 0 0 20 0 13 15 0 10 1 0 2 8 4 0 15 0 3 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 284 W S e 48.2 2js7_A 5 0 0 0 0 10 0 15 0 15 4 0 0 0 10 0 0 5 36 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 285 F H b 1.4 2js7_A 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 286 W H b 8.8 2js7_A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 287 T H e 20.1 2js7_A 8 0 10 6 0 0 0 0 13 12 0 0 0 7 15 0 17 12 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 288 R H e 55.3 2js7_A 0 0 0 0 0 0 0 0 17 0 0 23 0 10 50 0 0 0 0 0 MUTAGEN:/note="R->A: Slightly reduced activity, and reduced interaction with TIRAP. Strongly reduced interaction with TIRAP; when associated with A-196.":DOMAIN:/note="TIR":MUTAGEN:/note="R->A: Slightly reduced activity, and reduced interaction with TIRAP. Strongly reduced interaction with TIRAP; when associated with A-196.":DOMAIN:/note="TIR" 289 L H b 1.7 2js7_A 0 0 0 0 0 0 0 8 0 92 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 290 A H b 0.0 2js7_A 29 0 0 0 0 0 0 0 11 0 0 0 0 10 49 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 291 K H e 34.0 2js7_A 16 0 0 0 14 0 0 0 36 0 0 12 0 0 4 0 8 10 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 292 A H e 23.2 2js7_A 97 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 293 L H b 0.0 2js7_A 0 0 0 0 0 0 0 20 0 70 10 0 0 0 0 0 0 0 0 0 DOMAIN:/note="TIR":DOMAIN:/note="TIR" 294 S H e 20.3 2js7_A 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 82 0 0 0 0 295 L S e 37.6 2js7_A 0 0 0 0 0 0 0 0 0 91 9 0 0 0 0 0 0 0 0 0 296 P e 29.5 2js7_A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0