site aa pred_sec pred_expbur pred_accessibility pdb_asym_id hetero nucleotide compound metal otherpoly homo precipitant A C D E F G H I K L M N P Q R S T V W Y feature_table variant 1 M e 70.0 4nqk_D UBC_HUMAN:Ubiquitin[75 aa] 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DISORDER:predicted by DISOPRED:DOMAIN:/note="CARD 1" 2 T H e 26.6 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 DOMAIN:/note="CARD 1":DISORDER:predicted by DISOPRED:DOMAIN:/note="CARD 1" 3 T H e 44.2 4nqk_D 68 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32 0 0 0 DOMAIN:/note="CARD 1":DISORDER:predicted by DISOPRED:DOMAIN:/note="CARD 1" 4 E H e 57.3 4nqk_D UBC_HUMAN:Ubiquitin[75 aa]:Ubiquitin[73 aa] 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DISORDER:predicted by DISOPRED:DOMAIN:/note="CARD 1" 5 Q H e 29.6 4nqk_D UBC_HUMAN:Ubiquitin[75 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DISORDER:predicted by DISOPRED:DOMAIN:/note="CARD 1" 6 R H e 25.3 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 7 R H e 60.5 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[75 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 34 66 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" R->C:LB/B:rs1081383: -; 8 S H e 33.6 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[75 aa] 0 0 0 0 0 0 0 0 0 0 0 68 0 0 0 32 0 0 0 0 MOD_RES:/note="(Microbial infection) Phosphoserine":DOMAIN:/note="CARD 1":MOD_RES:/note="(Microbial infection) Phosphoserine":DOMAIN:/note="CARD 1" 9 L H b 0.0 4nqk_D 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 10 Q H e 50.0 4nqk_D 0 0 0 0 0 0 33 0 0 0 0 0 0 67 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 11 A H e 66.1 4nqk_D UBC_HUMAN:Ubiquitin[73 aa] 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 12 F T e 27.3 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[75 aa] 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 13 Q H e 43.9 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 33 0 0 0 0 0 0 0 32 34 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 14 D H e 32.1 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[75 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 15 Y H e 20.9 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[75 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 16 I H b 0.0 4nqk_D 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 0 0 33 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 17 R H e 34.0 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 34 0 0 0 0 0 66 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 18 K H e 29.2 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 19 T H b 0.0 4nqk_D 0 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 66 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 20 L b 0.6 4nqk_D 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 21 D b 1.9 4nqk_D 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 22 P H b 0.0 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 23 T H b 7.8 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 24 Y H b 5.2 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 25 I H b 0.0 4nqk_D 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 26 L H b 3.9 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 27 S H e 62.5 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 28 Y H e 45.2 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[72 aa]:Ubiquitin[71 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 29 M H b 0.0 4nqk_D 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 30 A G e 47.3 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 66 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 31 P G e 79.1 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[72 aa]:Ubiquitin[71 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 0 66 0 0 34 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 32 W G e 26.3 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[72 aa]:Ubiquitin[71 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 33 F S b 5.7 4nqk_D 0 0 0 0 66 0 0 0 0 34 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 34 R e 55.3 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 34 0 0 0 0 0 0 0 0 0 0 66 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 35 E H e 74.9 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 68 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 36 E H e 66.3 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 33 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 37 E H b 7.5 4nqk_D 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 38 V H b 19.3 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 39 Q H e 72.4 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 40 Y H e 49.1 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 33 0 0 0 0 0 0 0 0 0 0 0 0 67 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 41 I H b 0.0 4nqk_D 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 42 Q H e 40.3 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 43 A H e 28.6 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 44 E H b 10.6 4nqk_D 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 45 K H e 26.4 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 46 N H e 79.4 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 47 N H e 85.5 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 64 0 0 0 0 36 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 48 K H e 67.0 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 36 0 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)":DOMAIN:/note="CARD 1":CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)":DOMAIN:/note="CARD 1" 49 G e 22.6 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 50 P H e 27.9 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 36 64 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 51 M H e 45.4 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 0 57 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 52 E H e 49.7 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 53 A H b 0.0 4nqk_D 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 54 A H b 0.0 4nqk_D 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 55 T H e 32.5 4nqk_D 0 0 0 36 0 0 0 0 0 0 0 0 0 0 0 44 21 0 0 0 MUTAGEN:/note="T->I: No IRF3 signaling activity. No effect on dsRNA binding.":DOMAIN:/note="CARD 1":MUTAGEN:/note="T->I: No IRF3 signaling activity. No effect on dsRNA binding.":DOMAIN:/note="CARD 1" 56 L H b 4.5 4nqk_D 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 57 F H b 0.0 4nqk_D 0 0 0 0 64 0 0 0 0 36 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 58 L H b 5.1 4nqk_D 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 59 K H e 50.9 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 21 0 0 0 0 44 0 36 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 60 F H b 13.4 4nqk_D 0 0 0 0 42 0 0 0 0 0 0 0 0 0 0 0 36 0 0 22 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 61 L H b 0.0 4nqk_D 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 62 L H b 10.7 4nqk_D 0 0 0 36 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 63 E T e 46.7 4nqk_D 0 0 0 42 0 0 0 0 22 0 0 0 0 36 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 64 L b 1.1 4nqk_D 0 0 0 0 0 36 0 0 0 64 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 65 Q e 89.8 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 66 E S e 55.3 4nqk_D 0 0 0 42 0 0 0 0 0 0 0 0 36 0 0 22 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 67 E T e 93.0 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[72 aa]:Ubiquitin[71 aa] 0 0 0 64 0 0 0 0 0 36 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 68 G T e 59.5 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[72 aa]:Ubiquitin[71 aa] 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 69 W H b 0.8 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 70 F H b 11.5 4nqk_D 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 71 R H e 44.7 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[72 aa]:Ubiquitin[71 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 58 42 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 72 G H b 6.0 4nqk_D 22 0 0 0 0 42 0 0 0 0 36 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 73 F H b 0.0 4nqk_D 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 74 L H b 1.7 4nqk_D 0 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 0 36 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 75 D H e 37.0 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[72 aa]:Ubiquitin[71 aa] 0 0 64 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 76 A H b 1.8 4nqk_D 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 77 L H b 0.0 4nqk_D 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 78 D H e 38.3 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[72 aa]:Ubiquitin[71 aa] 0 0 21 36 0 0 0 0 0 0 0 22 0 0 0 0 0 0 0 22 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 79 H H e 52.9 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[72 aa]:Ubiquitin[71 aa] 0 0 0 0 0 0 78 0 0 0 0 0 0 22 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 80 A H b 4.5 4nqk_D 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 81 G T e 26.2 4nqk_D 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 82 Y b 0.0 4nqk_D 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 0 0 0 0 64 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 83 S T e 39.8 4nqk_D 36 44 0 0 0 0 0 0 0 0 0 0 0 0 0 21 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 84 G T e 23.8 4nqk_D 36 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 85 L H b 0.0 4nqk_D 0 0 0 0 0 0 0 0 0 64 0 0 0 0 36 0 0 0 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 86 Y H b 15.7 4nqk_D UBC_HUMAN:Ubiquitin[72 aa]:Ubiquitin[71 aa] 0 44 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 87 E H e 47.7 4nqk_D 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 DOMAIN:/note="CARD 1":DOMAIN:/note="CARD 1" 88 A H b 2.7 4nqk_D 64 0 0 0 0 0 0 0 36 0 0 0 0 0 0 0 0 0 0 0 89 I H b 0.0 4nqk_D 0 0 0 0 0 0 0 64 0 0 0 0 36 0 0 0 0 0 0 0 90 E H e 41.2 4nqk_D UBC_HUMAN:Ubiquitin[75 aa] 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 91 S T e 51.6 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[75 aa] 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 64 0 0 0 0 92 W T e 29.9 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[75 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0 64 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 93 D e 55.6 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[75 aa] 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 94 F b 3.8 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[75 aa] 0 0 0 0 64 0 0 0 0 36 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 95 K H e 76.9 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[75 aa] 0 0 0 0 0 0 0 0 21 0 0 0 36 44 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 96 K H e 41.0 4nqk_D 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 36 0 0 0 0 CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)":DOMAIN:/note="CARD 2":CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)":DOMAIN:/note="CARD 2" 97 I H b 0.6 4nqk_D 0 0 0 0 0 0 0 64 0 0 0 0 36 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 98 E H e 44.2 4nqk_D UBC_HUMAN:Ubiquitin[73 aa]:Ubiquitin[75 aa] 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 99 K H e 66.5 4nqk_D 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 36 0 0 0 0 MUTAGEN:/note="K->R: Little or no effect on ubiquitination of the 2 CARD domain. Abolishes ubiquitination by RNF125." ECO:0000269|PubMed:26471729":DOMAIN:/note="CARD 2":MUTAGEN:/note="K->R: Little or no effect on ubiquitination of the 2 CARD domain. Abolishes ubiquitination by RNF125." ECO:0000269|PubMed:26471729":DOMAIN:/note="CARD 2" 100 L H b 1.1 4nqk_D 0 0 0 0 0 0 36 0 0 64 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 101 E H e 26.1 4nqk_D 0 0 36 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 102 E H e 41.7 4nqk_D 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 103 Y H b 19.1 4nqk_D 0 36 0 0 0 0 22 0 0 0 0 0 0 0 0 0 0 0 0 42 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 104 R H b 4.3 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 36 0 0 0 0 64 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 105 L H e 68.5 4nqk_D UBC_HUMAN:Ubiquitin[72 aa]:Ubiquitin[71 aa] 0 0 0 0 0 0 36 0 0 43 0 0 0 0 0 22 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 106 L H b 16.3 4nqk_D UBC_HUMAN:Ubiquitin[71 aa] 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 107 L H b 0.0 4nqk_D 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 108 K H e 66.5 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 21 0 0 0 0 0 44 0 36 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 109 R H e 88.1 4nqk_D UBC_HUMAN:Ubiquitin[72 aa]:Ubiquitin[71 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 36 0 0 0 0 64 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 110 L H b 9.0 4nqk_D UBC_HUMAN:Ubiquitin[72 aa]:Ubiquitin[71 aa] 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 111 Q H e 24.0 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 22 0 0 0 0 0 0 0 0 0 78 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 112 P H e 56.6 4nqk_D UBC_HUMAN:Ubiquitin[71 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 113 E H e 45.2 4nqk_D UBC_HUMAN:Ubiquitin[72 aa]:Ubiquitin[71 aa] 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 114 F H b 0.0 4nqk_D 0 0 0 0 64 0 0 0 0 36 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 115 K H b 3.3 4nqk_D 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 0 0 36 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 116 T H e 81.2 4nqk_D 22 0 36 0 0 0 0 0 0 0 0 0 0 0 0 0 42 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 117 R H b 6.7 4nqk_D 0 0 0 0 0 0 0 0 36 0 0 0 0 0 21 0 44 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 118 I b 1.2 4nqk_D 0 0 0 0 0 0 0 42 0 36 0 0 0 0 0 0 0 22 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 119 I e 65.5 4nqk_D 0 0 22 0 0 0 0 21 0 36 0 22 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 120 P H b 0.0 4nqk_D 0 0 0 0 0 0 0 36 0 0 0 0 64 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 121 T H e 59.1 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 22 0 0 58 0 0 0 0 21 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 122 D H e 37.7 4nqk_D 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 123 I H b 0.6 4nqk_D 0 0 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 36 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 124 I H b 5.8 4nqk_D 0 0 0 0 0 0 0 21 0 79 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 125 S T e 53.1 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 36 0 0 0 0 0 0 0 0 0 22 0 0 43 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 126 D G e 37.0 4nqk_D 0 0 21 44 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 127 L G b 0.0 4nqk_D 0 36 0 0 0 0 0 22 0 43 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 128 S G e 42.2 4nqk_D 22 0 0 0 36 0 0 0 0 0 0 0 0 0 0 43 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 129 E T e 47.7 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 130 C T b 0.0 4nqk_D 0 64 0 0 0 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 131 L S b 1.7 4nqk_D 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 132 I b 0.6 4nqk_D 0 0 0 0 0 0 0 64 0 36 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 133 N H e 72.7 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 43 0 0 0 22 36 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 134 Q H e 36.2 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 64 0 0 0 36 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 135 E H b 0.0 4nqk_D 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 136 C H b 13.3 4nqk_D 0 64 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 137 E H e 61.8 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 64 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 138 E H e 35.7 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 64 0 0 0 0 0 0 0 36 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DISORDER:predicted by DISOPRED:DOMAIN:/note="CARD 2" 139 I H b 0.0 4nqk_D 0 0 0 0 0 0 0 64 0 0 0 0 0 0 36 0 0 0 0 0 DOMAIN:/note="CARD 2":DISORDER:predicted by DISOPRED:DOMAIN:/note="CARD 2" 140 L H e 48.9 4nqk_D 0 0 0 0 0 0 0 36 0 42 0 0 0 0 22 0 0 0 0 0 DOMAIN:/note="CARD 2":DISORDER:predicted by DISOPRED:DOMAIN:/note="CARD 2" 141 Q H e 62.8 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 0 0 64 0 36 0 0 0 0 DOMAIN:/note="CARD 2":DISORDER:predicted by DISOPRED:DOMAIN:/note="CARD 2" 142 I H b 17.0 4nqk_D 36 0 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DISORDER:predicted by DISOPRED:DOMAIN:/note="CARD 2" 143 C H b 9.3 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 36 42 0 0 0 0 0 0 0 0 0 0 0 0 22 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 144 S H e 63.3 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 22 0 0 36 0 0 0 0 0 0 0 0 0 42 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 145 T H e 80.5 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 22 43 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 146 K T e 76.9 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 36 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 147 G e 25.0 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 148 M H e 33.3 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 0 0 22 21 36 0 0 22 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 149 M H e 58.5 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 36 0 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 150 A H e 21.4 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 151 G H b 0.0 4nqk_D 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DISORDER:predicted by DISOPRED:DOMAIN:/note="CARD 2" 152 A H b 0.0 4nqk_D 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 153 E H e 45.7 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 64 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 154 K H b 18.9 4nqk_D 0 0 0 36 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)" ECO:0000269|PubMed:24755855":MUTAGEN:/note="K->R: Reduction of ubiquitination. Reduction of INFB induction.":DOMAIN:/note="CARD 2":CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)" ECO:0000269|PubMed:24755855":MUTAGEN:/note="K->R: Reduction of ubiquitination. Reduction of INFB induction.":DOMAIN:/note="CARD 2" 155 L H b 0.0 4nqk_D 0 0 0 0 0 0 0 0 0 56 44 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 156 V H b 1.3 4nqk_D 22 0 0 0 0 0 0 0 0 36 0 0 0 0 0 0 0 42 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 157 E H e 38.2 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 64 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 158 C H b 0.0 4nqk_D 0 64 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 159 L H b 0.0 4nqk_D 0 0 0 0 0 0 0 36 0 64 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 160 L H e 25.8 4nqk_D DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[188 aa] 0 0 0 0 0 0 0 22 0 42 0 0 0 0 0 0 0 36 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 161 R T b 7.9 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 0 0 36 64 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 162 S b 0.0 4nqk_D 3 1 2 2 1 3 1 2 2 3 1 2 2 2 2 67 2 2 0 1 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 163 D b 0.6 4nqk_D 3 1 66 2 1 3 1 2 2 3 1 2 2 2 2 3 2 2 0 1 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 164 K b 9.9 4nqk_D 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)" ECO:0000269|PubMed:24755855":MUTAGEN:/note="K->R: Reduction of ubiquitination. Reduction of INFB induction.":DOMAIN:/note="CARD 2":CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)" ECO:0000269|PubMed:24755855":MUTAGEN:/note="K->R: Reduction of ubiquitination. Reduction of INFB induction.":DOMAIN:/note="CARD 2" 165 E T e 36.7 4nqk_D 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 166 N T e 61.8 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 167 W H b 0.0 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 168 P H b 4.7 4nqk_D 0 0 0 0 36 0 0 0 0 0 0 0 64 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 169 K H e 40.6 4nqk_D 0 0 0 0 0 0 0 0 64 0 0 0 0 0 0 36 0 0 0 0 MUTAGEN:/note="K->R: Little or no effect on ubiquitination of the 2 CARD domains.":DOMAIN:/note="CARD 2":MUTAGEN:/note="K->R: Little or no effect on ubiquitination of the 2 CARD domains.":DOMAIN:/note="CARD 2" 170 T H b 13.0 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78 22 0 0 DOMAIN:/note="CARD 2":DISORDER:predicted by DISOPRED:DOMAIN:/note="CARD 2" 171 L H b 0.0 4nqk_D 0 0 0 0 36 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="CARD 2":DOMAIN:/note="CARD 2" 172 K H b 17.5 4nqk_D 0 0 0 0 0 0 0 0 42 36 0 0 0 22 0 0 0 0 0 0 CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)" ECO:0000269|PubMed:24755855, ECO:0000269|PubMed:28469175":MUTAGEN:/note="K->R: Complete loss of ubiquitination. No interaction with MAVS/IPS1. No induction of IFN-beta." ECO:0000269|PubMed:19484123":DOMAIN:/note="CARD 2":CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)" ECO:0000269|PubMed:24755855, ECO:0000269|PubMed:28469175":MUTAGEN:/note="K->R: Complete loss of ubiquitination. No interaction with MAVS/IPS1. No induction of IFN-beta." ECO:0000269|PubMed:19484123":DOMAIN:/note="CARD 2" 173 L H e 68.5 4nqk_D 0 0 36 0 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 174 A H b 3.6 4nqk_D 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 175 L H b 0.0 4nqk_D 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 176 E H e 50.8 4nqk_D 0 0 0 64 0 0 0 0 0 0 0 0 0 0 36 0 0 0 0 0 177 K H e 57.5 4nqk_D 0 0 0 0 0 0 0 0 64 0 0 0 0 36 0 0 0 0 0 0 178 E S e 24.1 4nqk_D 0 0 22 42 0 0 0 0 0 0 0 0 0 0 0 0 36 0 0 0 179 R e 33.6 4nqk_D 0 0 0 22 0 36 0 0 0 0 0 22 0 0 21 0 0 0 0 0 180 N e 24.2 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 56 0 0 0 44 0 0 0 0 181 K S e 75.0 4nqk_D 0 0 36 0 0 0 0 0 43 0 0 0 0 0 22 0 0 0 0 0 CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)":MUTAGEN:/note="K->R: Little or no effect on ubiquitination of the 2 CARD domains.":CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)":MUTAGEN:/note="K->R: Little or no effect on ubiquitination of the 2 CARD domains." 182 F G b 0.5 4nqk_D 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183 S G b 17.2 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 0 0 36 0 64 0 0 0 0 184 E G e 41.7 4nqk_D UBC_HUMAN:Ubiquitin[71 aa] 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185 L G e 48.9 4nqk_D UBC_HUMAN:Ubiquitin[72 aa]:Ubiquitin[71 aa] 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 186 W S b 0.0 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 187 I e 59.6 4nqk_D 0 0 0 0 0 0 0 43 0 0 22 36 0 0 0 0 0 0 0 0 188 V e 98.7 4nqk_D 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 189 E e 28.1 2lwd_A 0 0 79 21 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190 K e 72.2 2lwd_A 0 0 36 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 MUTAGEN:/note="K->R: Little or no effect on ubiquitination of the 2 CARD domains.":MUTAGEN:/note="K->R: Little or no effect on ubiquitination of the 2 CARD domains." 191 G 0 0 0 0 0 75 0 25 0 0 0 0 0 0 0 0 0 0 0 0 192 I 15 0 0 0 15 0 0 14 0 25 0 0 0 0 0 0 0 30 0 0 193 K 0 0 0 15 0 0 0 0 30 0 0 0 25 0 30 0 0 0 0 0 MUTAGEN:/note="K->R: Little or no effect on ubiquitination of the 2 CARD domains.":MUTAGEN:/note="K->R: Little or no effect on ubiquitination of the 2 CARD domains.":DISORDER:predicted by DISOPRED 194 D 0 0 30 25 0 0 0 0 0 0 0 0 0 30 15 0 0 0 0 0 DISORDER:predicted by DISOPRED 195 V 31 0 0 0 0 0 0 0 0 22 0 0 0 0 0 0 23 24 0 0 DISORDER:predicted by DISOPRED 196 E 0 0 0 46 0 0 0 0 12 0 0 0 0 0 0 42 0 0 0 0 DISORDER:predicted by DISOPRED 197 T 0 19 0 0 0 0 0 0 0 23 12 0 22 0 0 12 11 0 0 0 DISORDER:predicted by DISOPRED 198 E 0 0 0 34 23 0 0 0 25 0 0 0 0 0 0 0 19 0 0 0 DISORDER:predicted by DISOPRED 199 D 0 0 78 0 0 0 0 0 22 0 0 0 0 0 0 0 0 0 0 0 DISORDER:predicted by DISOPRED 200 L 0 0 0 12 0 0 0 0 0 24 45 0 0 0 0 19 0 0 0 0 DISORDER:predicted by DISOPRED 201 E 0 0 12 46 0 0 0 0 0 0 0 0 0 0 0 19 23 0 0 0 DISORDER:predicted by DISOPRED 202 D 0 0 36 22 0 0 0 0 0 0 0 0 0 0 0 23 0 19 0 0 DISORDER:predicted by DISOPRED 203 K 0 0 0 12 0 35 0 0 11 0 0 0 0 0 23 0 19 0 0 0 DISORDER:predicted by DISOPRED 204 M 12 0 0 0 0 22 0 0 0 0 24 23 0 0 0 0 19 0 0 0 DISORDER:predicted by DISOPRED 205 E 0 0 0 42 0 22 0 0 12 0 0 0 0 23 0 0 0 0 0 0 DISORDER:predicted by DISOPRED 206 T 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41 47 0 0 0 DISORDER:predicted by DISOPRED 207 S 0 12 23 0 0 19 0 0 0 0 0 22 0 0 0 24 0 0 0 0 DISORDER:predicted by DISOPRED 208 D 0 0 24 0 0 0 0 0 0 0 0 0 0 23 0 53 0 0 0 0 DISORDER:predicted by DISOPRED 209 I 0 0 0 0 0 0 0 24 0 22 0 0 23 0 0 0 0 31 0 0 DISORDER:predicted by DISOPRED 210 Q 0 0 0 0 0 0 0 0 22 0 0 0 23 36 0 19 0 0 0 0 DISORDER:predicted by DISOPRED 211 I 0 19 0 0 0 0 0 59 0 0 0 0 0 0 22 0 0 0 0 0 212 F 0 0 0 0 55 23 0 0 22 0 0 0 0 0 0 0 0 0 0 0 DISORDER:predicted by DISOPRED 213 Y 0 0 19 23 22 0 0 12 0 0 0 0 0 0 0 0 0 0 0 24 DISORDER:predicted by DISOPRED 214 Q 0 0 0 19 0 0 0 0 12 0 0 0 0 47 0 22 0 0 0 0 DISORDER:predicted by DISOPRED 215 E 0 0 23 58 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 DISORDER:predicted by DISOPRED 216 D 0 0 23 43 0 0 0 21 0 13 0 0 0 0 0 0 0 0 0 0 DISORDER:predicted by DISOPRED 217 P 0 0 21 0 0 13 0 0 0 0 0 0 53 0 0 13 0 0 0 0 DISORDER:predicted by DISOPRED 218 E 0 0 13 32 0 21 13 0 0 0 0 0 22 0 0 0 0 0 0 0 DISORDER:predicted by DISOPRED 219 C 0 21 21 13 0 0 0 0 0 0 0 24 0 0 0 0 22 0 0 0 DISORDER:predicted by DISOPRED 220 Q 0 0 0 13 0 0 0 0 0 0 0 0 0 74 0 13 0 0 0 0 DISORDER:predicted by DISOPRED 221 N 0 0 0 0 0 0 22 0 0 0 0 78 0 0 0 0 0 0 0 0 DISORDER:predicted by DISOPRED 222 L 0 0 0 0 0 0 0 0 22 52 13 0 0 0 0 0 0 13 0 0 DISORDER:predicted by DISOPRED 223 S 13 0 21 0 0 13 0 0 0 22 0 0 0 0 0 32 0 0 0 0 DISORDER:predicted by DISOPRED 224 E 12 0 13 22 0 0 0 0 0 0 0 0 0 21 12 20 0 0 0 0 DISORDER:predicted by DISOPRED 225 N 0 0 12 0 0 0 13 0 13 0 0 30 0 0 12 0 0 20 0 0 DISORDER:predicted by DISOPRED 226 S 12 0 13 0 0 0 0 0 0 0 0 0 10 0 0 65 0 0 0 0 DISORDER:predicted by DISOPRED 227 C 13 20 0 13 0 22 0 0 0 0 0 0 0 0 0 32 0 0 0 0 DISORDER:predicted by DISOPRED 228 P 0 0 0 0 0 0 0 0 0 11 0 0 70 0 0 9 10 0 0 0 229 P 1 0 17 11 1 1 0 1 1 2 11 1 28 1 1 21 1 1 0 1 230 S 18 0 1 1 0 7 0 1 1 1 0 1 7 0 1 35 26 1 0 0 231 E 12 0 0 37 0 0 0 0 0 0 11 0 0 8 0 19 5 0 8 0 232 V 6 0 7 0 0 0 0 0 0 23 11 0 0 0 0 0 9 39 0 0 233 S 1 0 1 1 0 1 0 1 1 1 0 1 6 0 1 44 24 1 0 17 234 D 5 0 39 1 0 1 0 1 1 1 0 7 14 7 1 6 17 1 0 0 235 T 8 8 0 6 0 0 0 0 0 0 0 10 5 14 0 16 29 0 0 0 236 N 7 0 6 0 0 0 5 0 6 0 0 32 0 8 0 13 0 8 0 12 237 L 1 0 9 1 1 5 0 13 1 46 0 1 1 1 6 8 5 1 0 0 238 Y 21 0 1 1 1 9 5 1 1 7 6 1 1 1 1 1 1 14 0 26 239 S e 71.9 7jl1_A 18 0 1 2 1 6 1 1 1 2 1 1 12 1 1 37 11 2 0 1 240 P e 92.2 7jl1_A 6 0 1 2 1 2 1 1 8 7 1 15 41 1 1 2 8 2 0 1 241 F e 109.6 8dvs_A ADP 1 0 1 1 31 3 0 1 1 24 0 4 1 0 3 1 1 1 0 27 242 K e 87.7 8dvs_A ADP 0 2 2 24 0 0 3 0 19 0 0 6 0 12 16 0 13 0 0 0 243 P e 34.1 8dvs_A 15 0 0 0 0 0 0 4 0 7 0 0 56 0 0 0 6 10 0 0 244 R e 39.5 8dvs_A ADP 0 0 0 0 0 3 0 0 0 0 0 0 0 6 92 0 0 0 0 0 245 N H e 57.6 8dvs_A 6 0 21 13 0 4 0 0 12 2 0 7 6 4 5 11 2 0 1 6 246 Y H b 0.4 8dvs_A 0 0 0 0 0 0 0 0 0 0 6 0 0 0 0 2 0 0 0 93 247 Q H b 4.6 8dvs_A ADP 6 0 0 3 0 0 0 0 0 0 0 0 0 92 0 0 0 0 0 0 248 L H e 43.8 8dvs_A 1 0 0 0 15 0 0 5 1 42 5 0 0 6 0 0 1 16 4 4 249 E H b 17.1 8dvs_A 1 0 10 56 0 0 1 2 3 0 0 11 0 6 3 3 2 2 0 0 250 L H b 0.0 8dvs_A BU3 8 0 0 2 1 0 0 24 0 29 19 0 0 0 0 0 0 17 0 0 251 A H b 0.9 8dvs_A 15 5 1 1 13 7 0 5 1 15 0 1 1 1 1 4 4 17 0 8 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 252 L T e 56.7 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[668 aa] 2 0 2 26 11 0 3 0 7 15 2 4 0 11 5 1 0 8 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 253 P T e 20.2 8dvs_A 18 1 2 30 0 0 0 3 10 0 0 5 11 2 10 3 2 5 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 254 A T b 1.8 8dvs_A 53 0 0 1 0 5 2 0 0 1 0 0 0 4 10 20 1 1 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 255 M T e 23.2 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa] 20 0 0 1 3 1 0 2 2 48 8 0 0 4 0 3 4 3 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 256 K T e 59.4 8dvs_A 1 0 9 10 7 1 0 0 46 8 0 2 0 4 5 1 2 1 0 4 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 257 G T e 70.2 8dvs_A GOL 6 3 9 2 10 28 1 2 5 3 2 4 2 5 3 6 5 4 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 258 K S e 24.5 8dvs_A 1 0 2 21 0 2 13 1 20 1 0 2 1 20 11 4 1 1 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 259 N b 10.9 8dvs_A GOL 0 0 4 1 0 0 0 0 2 0 0 92 0 1 0 0 0 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 260 T B b 0.0 8dvs_A 0 0 0 0 0 2 0 26 0 17 4 2 0 0 0 0 42 8 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 261 I b 2.3 8dvs_A 0 0 0 0 0 0 0 58 0 39 0 0 0 0 0 0 0 3 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 262 I b 0.6 8dvs_A ETF:BU3 20 6 0 0 0 4 0 14 0 7 0 0 0 0 0 0 0 49 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 263 C B b 8.7 8dvs_A ETF:BU3 31 23 0 0 5 0 0 0 0 0 1 0 0 2 0 5 1 24 3 4 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 264 A b 2.7 8dvs_A ETF:BU3 18 0 0 0 0 0 0 6 0 62 14 0 0 0 0 0 0 0 0 0 BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding":BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding" 265 P e 41.1 8dvs_A ADP SO4:BU3 0 0 22 5 3 9 0 0 0 0 0 6 50 0 2 2 0 0 0 0 BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding":BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding" 266 T T e 21.4 8dvs_A ADP DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] SO4:BEF:ALF 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 95 0 0 0 BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding":BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding" 267 G T e 25.0 8dvs_A ADP DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa] SO4 3 0 3 0 0 94 0 0 0 0 0 0 0 0 0 0 0 0 0 0 BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding":BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding" 268 C S b 0.0 8dvs_A ADP SO4:ETF:BU3 17 6 0 0 0 0 0 3 0 20 3 0 0 0 0 41 9 0 0 0 BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding":BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding" C->F:LP/P:rs7862048: Singleton-Merten syndrome 2 (SGMRT2) ; 269 G e 33.3 8dvs_A ADP SO4:BU3 0 0 3 0 0 95 0 0 0 0 0 0 0 0 0 0 0 0 0 0 BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding":BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding" 270 K H b 11.8 8dvs_A ADP MG SO4:BEF:ETF:BU3:ALF 0 0 0 0 0 0 0 0 97 0 0 0 0 0 0 0 0 0 0 0 MUTAGEN:/note="K->A: No IRF3 signaling activity. Loss of dsRNA- induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway." ECO:0000269|PubMed:15708988, ECO:0000269|PubMed:19211564":BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding":MUTAGEN:/note="K->A: No IRF3 signaling activity. Loss of dsRNA- induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway." ECO:0000269|PubMed:15708988, ECO:0000269|PubMed:19211564":BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding" 271 T H e 27.9 8dvs_A ADP MG DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] SO4:BU3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 95 0 0 0 BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding":BINDING:/ligand="ATP" /ligand_id="ChEBI:CHEBI:30616":DOMAIN:/note="Helicase ATP-binding" 272 F H b 11.5 8dvs_A ADP BU3 6 0 0 4 36 0 11 0 0 22 3 6 0 5 6 0 0 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 273 V H b 0.7 8dvs_A BU3 7 0 0 0 0 0 0 71 0 3 0 0 0 0 0 0 0 17 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 274 S H b 0.8 8dvs_A 88 0 0 0 0 0 0 0 0 0 0 0 0 0 3 3 2 0 0 4 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 275 L H b 4.5 8dvs_A 22 0 0 3 0 0 0 13 0 16 6 0 0 0 0 6 1 31 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 276 L H b 9.6 8dvs_A 0 0 0 0 2 0 0 0 3 50 13 0 0 0 0 0 14 11 0 4 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 277 I H b 1.8 8dvs_A 6 2 0 0 0 0 0 12 0 30 0 0 4 0 12 0 4 28 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 278 C H b 0.0 8dvs_A 13 4 0 0 0 0 0 32 2 13 24 0 0 0 0 2 5 4 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 279 E H e 24.6 8dvs_A 4 0 8 7 0 1 3 3 29 15 2 1 1 2 10 1 2 4 0 8 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 280 H H e 47.6 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 7 0 4 6 1 7 20 1 4 1 0 18 1 6 13 4 1 1 0 5 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 281 H H b 6.8 8dvs_A 1 0 1 26 10 3 24 3 3 3 2 1 1 6 2 4 3 1 0 7 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 282 L T b 8.4 8dvs_A 3 0 0 0 2 1 0 15 2 63 0 0 0 0 1 3 1 2 3 4 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 283 K T e 49.1 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[669 aa] 7 0 7 17 0 1 1 4 11 4 0 12 0 9 21 2 2 2 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 284 K S e 59.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa] 4 0 13 5 4 6 2 3 11 7 0 2 0 4 11 3 4 1 14 3 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 285 F S e 20.1 8dvs_A MG DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[653 aa] 1 3 6 1 32 1 3 2 5 4 6 4 1 5 11 3 2 7 0 4 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 286 P e 62.0 8dvs_A MG DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 7 0 3 3 3 4 3 5 4 6 1 1 32 3 16 4 1 1 1 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 287 Q T e 104.1 8dvs_A MG DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 6 1 1 8 1 3 2 4 10 6 0 8 3 12 11 5 3 1 15 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 288 G T e 102.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 6 2 4 6 1 26 2 4 9 2 1 5 6 4 1 6 12 2 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 289 Q e 62.2 8dvs_A MG DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 5 1 11 7 1 1 1 1 23 3 0 14 2 10 8 7 2 2 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 290 K e 57.1 8dvs_A 6 0 6 9 1 14 0 1 11 1 0 6 12 0 6 17 7 2 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 291 G b 2.4 8dvs_A 9 1 7 2 6 36 6 0 9 1 3 0 3 0 3 12 1 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 292 K b 14.2 8dvs_A 0 0 0 0 1 0 0 0 52 5 0 2 0 6 28 0 0 3 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 293 V b 0.0 8dvs_A 8 7 0 0 2 0 0 40 0 5 3 0 0 0 2 2 7 25 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 294 V E b 0.0 8dvs_A 7 0 0 0 3 0 0 22 0 11 0 0 0 0 0 5 1 43 9 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 295 F E b 1.0 8dvs_A 0 0 0 0 69 0 0 6 0 0 0 0 0 0 0 0 0 6 7 12 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 296 F E b 0.0 8dvs_A 1 0 0 0 21 0 0 5 0 47 10 0 0 0 0 0 4 11 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 297 A b 0.0 8dvs_A 48 3 0 0 0 0 0 0 0 2 0 0 0 0 0 0 9 36 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 298 N S e 42.4 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 MG DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 0 0 10 3 0 0 0 1 0 1 0 18 61 0 0 0 2 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 299 Q S e 24.5 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 2 0 0 0 0 0 0 0 14 6 4 0 0 5 4 15 47 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 300 I H e 33.3 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 5 0 0 2 0 0 0 3 24 1 0 0 0 0 9 0 0 53 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 301 P H e 23.3 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:p2dsRNA:p1dsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 25 0 0 2 0 0 4 0 1 1 1 8 39 1 0 6 7 2 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 302 V H b 6.7 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 0 0 0 0 0 0 0 0 0 80 0 0 0 5 0 2 4 10 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 303 Y H b 2.6 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 21 10 0 0 2 0 0 0 0 1 0 0 0 0 4 2 0 53 0 5 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 304 E H e 43.7 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa]:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 21 0 0 18 7 1 1 2 3 5 1 0 0 6 7 10 9 0 0 9 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 305 Q H e 30.6 8dvs_A ADP DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 0 0 0 10 0 0 0 0 0 0 4 0 0 84 0 0 0 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 306 Q H b 2.0 8dvs_A 4 0 0 0 0 0 5 0 4 2 6 0 0 75 0 0 0 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 307 K H e 29.7 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 18 2 0 4 4 2 11 12 5 1 3 0 0 0 5 1 5 14 0 11 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 308 S H e 39.1 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 15 0 3 17 0 1 1 2 11 1 2 10 0 1 6 17 5 4 0 3 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 309 V H e 32.0 8dvs_A 27 0 4 5 3 0 1 4 0 7 0 2 0 2 2 4 2 31 0 4 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 310 F H b 0.0 8dvs_A 4 11 1 1 20 1 4 15 1 18 0 0 1 0 4 2 1 16 0 2 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 311 S H e 31.2 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa] 14 2 1 4 4 1 0 1 8 1 0 6 1 3 22 28 2 1 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 312 K H e 85.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa] 7 3 3 5 1 3 2 4 15 4 2 7 2 16 10 8 8 1 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 313 Y H e 28.3 8dvs_A 1 5 1 5 0 2 14 13 6 4 4 16 1 3 7 3 2 9 0 5 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 314 F H b 0.5 8dvs_A 5 2 1 1 9 2 0 9 2 35 4 0 6 0 1 4 11 4 0 3 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 315 E T e 55.3 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[178 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 7 0 24 18 2 7 0 1 2 3 0 6 12 3 1 8 3 2 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 316 R T e 78.7 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[169 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 7 0 1 7 5 3 0 12 13 9 1 1 9 9 8 4 1 7 0 2 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 317 H T e 39.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa] 5 0 4 3 5 3 9 1 11 8 4 6 9 3 3 6 1 12 0 5 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 318 G T e 75.0 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 10 2 1 3 1 29 1 1 3 2 2 3 1 5 4 9 5 14 3 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 319 Y b 15.7 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa] 6 0 4 3 10 5 8 14 2 8 4 3 1 1 2 9 4 5 4 9 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 320 R e 37.9 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] BU3:ETF 1 0 6 5 3 4 5 2 18 1 6 3 6 7 14 2 4 6 0 5 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 321 V E b 9.3 8dvs_A 5 8 0 0 5 3 1 14 0 10 7 0 0 0 3 0 8 28 0 7 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 322 T E e 21.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 15 8 1 3 4 8 0 5 10 5 0 0 0 4 3 8 16 6 1 2 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 323 G b 10.7 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 3 1 1 15 0 39 0 5 6 3 3 1 0 5 0 3 11 1 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 324 I b 2.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa] 9 0 4 1 4 2 0 17 0 34 5 0 0 3 0 5 2 10 0 3 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 325 S b 7.8 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 2 3 10 3 1 5 3 0 3 3 8 0 3 0 0 18 33 3 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 326 G T e 56.0 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 0 0 6 0 0 66 0 2 5 4 2 5 0 3 2 3 2 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 327 A T e 81.2 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 12 0 17 9 0 5 0 7 5 8 0 1 0 5 0 12 4 8 5 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 328 T T e 32.5 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 3 0 16 3 5 0 0 2 0 2 14 2 5 0 0 7 28 5 6 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 329 A e 31.2 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*.. BU3 12 0 0 1 3 16 3 1 10 5 0 2 4 6 7 15 3 4 5 2 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 330 E S e 53.8 8dvs_A RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:p3SLR30:OHSLR30:p3dsRNA24b DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[64.. BU3 1 0 16 22 0 2 0 0 3 4 0 1 8 7 4 10 5 5 6 4 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 331 N S e 81.8 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[64.. 2 0 12 7 0 10 3 0 10 3 5 7 1 15 6 11 6 1 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 332 V S e 35.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa]:Antiviral innate immune response receptor RIG-I[65..:Antiviral innate immune response receptor RIG-I[64.. 10 3 3 2 0 2 2 6 8 15 2 4 5 2 5 6 8 10 5 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 333 P e 37.2 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa]:Antiviral innate immune response receptor RIG-I[65..:Antiviral innate immune response receptor RIG-I[64.. 8 1 3 3 1 5 4 2 1 5 0 1 13 5 15 9 6 4 12 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 334 V H b 8.7 8dvs_A 14 2 4 6 7 0 0 7 3 1 0 2 0 2 7 3 15 9 16 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 335 E H e 59.8 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[65.. 6 0 21 30 0 4 1 0 12 2 0 4 3 6 5 5 0 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 336 Q H e 53.6 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa]:Antiviral innate immune response receptor RIG-I[65..:Antiviral innate immune response receptor RIG-I[64.. BU3:ETF 7 0 7 25 0 4 3 3 3 2 0 2 4 25 8 2 0 4 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 337 I H e 24.6 8dvs_A MG DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] BU3:ETF 9 0 0 11 7 0 5 20 0 13 3 0 0 5 2 0 3 15 4 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 338 V H b 3.3 8dvs_A 4 0 0 2 13 0 0 10 0 30 2 0 0 0 0 6 0 10 17 3 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 339 E H e 61.8 8dvs_A 8 1 5 25 0 4 0 0 20 7 0 2 0 8 6 11 3 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 340 N T e 47.9 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[674 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] BU3:ETF 3 2 6 8 0 5 0 0 22 0 0 22 0 3 5 16 4 0 1 3 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 341 N b 13.9 8dvs_A MG BU3:ETF 0 1 2 2 3 3 13 4 18 1 2 21 0 8 4 1 2 7 0 6 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 342 D S b 1.2 8dvs_A 1 0 22 11 0 1 2 0 5 1 8 2 0 18 26 1 2 1 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 343 I E b 0.0 8dvs_A 1 0 0 0 0 0 0 23 0 6 2 0 0 0 0 3 0 63 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 344 I E b 0.0 8dvs_A 2 0 0 0 22 0 0 25 0 29 2 0 0 0 0 0 0 19 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 345 I b 0.0 8dvs_A 0 0 0 0 21 0 0 18 0 5 0 0 0 0 0 0 0 56 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 346 L b 0.0 8dvs_A 11 16 0 0 0 2 0 4 0 8 28 0 0 0 3 16 10 2 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 347 T b 9.7 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 94 3 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 348 P H b 0.0 8dvs_A 25 6 0 0 0 0 6 0 0 0 0 0 43 0 0 6 6 0 0 7 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 349 Q H e 46.4 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 MG 8 0 2 20 0 4 4 0 0 0 1 0 3 56 0 0 0 0 0 2 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 350 I H b 15.2 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p2dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a BU3 0 2 0 0 0 0 0 34 7 6 2 0 0 0 4 3 10 32 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 351 L H b 0.0 8dvs_A 3 0 0 0 9 0 0 5 0 66 3 0 0 0 0 0 0 13 2 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 352 V H b 11.3 8dvs_A 8 0 3 14 6 0 2 5 0 33 3 4 0 3 0 1 0 12 0 7 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 353 N H e 33.3 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 BU3 0 0 24 2 0 0 3 2 1 2 2 35 0 12 4 4 7 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 354 N H b 9.1 8dvs_A BU3 23 9 23 0 2 0 0 3 0 5 2 10 0 2 2 3 4 9 0 4 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 355 L H b 17.4 8dvs_A 0 2 0 0 0 0 0 10 2 67 5 3 2 0 2 2 0 5 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 356 K H e 71.7 8dvs_A 8 0 0 7 0 0 2 2 24 9 1 1 0 4 17 16 8 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 357 K T e 76.9 8dvs_A 5 0 0 8 0 0 30 0 6 2 0 18 0 2 10 11 3 2 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 358 G T e 78.6 8dvs_A 12 3 2 5 0 53 1 0 0 1 0 4 0 0 0 16 0 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 359 T S b 13.0 8dvs_A 7 0 8 3 31 1 1 5 1 3 0 5 0 0 2 4 8 6 1 13 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 360 I b 9.4 8dvs_A 2 5 3 0 6 0 2 25 0 23 2 0 0 0 0 2 0 25 0 3 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 361 P S e 100.8 8dvs_A 14 1 14 3 2 4 1 2 5 6 1 6 16 2 2 6 4 8 1 2 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 362 S e 35.2 8dvs_A 6 4 10 4 1 3 0 2 15 4 4 5 9 0 16 13 3 0 0 2 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 363 L G b 0.0 8dvs_A 1 0 2 1 0 1 0 15 10 29 16 3 6 0 4 4 2 6 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 364 S G e 22.7 8dvs_A 4 0 18 10 0 0 2 0 6 1 0 6 0 6 5 34 4 0 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 365 I G e 43.9 8dvs_A 3 1 10 4 0 0 0 19 3 4 5 4 0 15 8 7 3 12 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 366 F b 0.0 8dvs_A 1 0 1 5 12 1 0 29 4 18 5 1 1 1 1 2 1 18 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 367 T S e 23.4 8dvs_A 9 13 2 0 0 4 1 2 6 0 0 18 0 0 2 25 10 8 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 368 L E b 0.0 8dvs_A 0 0 0 0 0 0 0 1 0 91 0 0 0 0 0 0 0 8 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 369 M E b 0.0 8dvs_A 0 0 0 0 0 0 0 15 0 58 7 0 0 0 0 0 0 16 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 370 I E b 0.0 8dvs_A 0 0 0 0 0 0 0 61 0 0 0 0 0 0 0 0 0 39 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 371 F E b 0.0 8dvs_A 3 0 0 0 43 1 0 20 0 12 2 0 0 0 0 0 0 16 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 372 D B b 13.6 8dvs_A MG DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 MOTIF:/note="DECH box":MUTAGEN:/note="DECH->AACA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding":MOTIF:/note="DECH box":MUTAGEN:/note="DECH->AACA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding" 373 E T b 12.1 8dvs_A MG DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] BEF:ALF 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 MOTIF:/note="DECH box":MUTAGEN:/note="DECH->AACA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding":MOTIF:/note="DECH box":MUTAGEN:/note="DECH->AACA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding" E->A:LP/P:rs7862048: Singleton-Merten syndrome 2 (SGMRT2) ; 374 C G b 0.0 8dvs_A 54 34 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 6 0 0 MOTIF:/note="DECH box":MUTAGEN:/note="DECH->AACA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding":MOTIF:/note="DECH box":MUTAGEN:/note="DECH->AACA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding" 375 H G b 3.7 8dvs_A 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 MOTIF:/note="DECH box":MUTAGEN:/note="DECH->AACA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding":MOTIF:/note="DECH box":MUTAGEN:/note="DECH->AACA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding" 376 N G b 14.5 8dvs_A RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:p3dsRNA24a MG BU3 0 0 4 0 0 0 51 0 4 7 0 10 0 0 21 4 0 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 377 T b 3.2 8dvs_A 49 18 0 0 0 2 0 0 0 0 0 0 0 0 0 6 21 4 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 378 S e 37.5 8dvs_A RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:p1dsRNA:OHdsRNA 0 1 0 0 0 3 4 10 17 5 4 4 4 3 3 13 25 4 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 379 K S e 84.9 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 1:dsRNA strand1:p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 0 0 4 0 0 43 0 0 28 4 0 0 0 5 8 3 2 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 380 Q S e 83.7 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 1:dsRNA strand1:p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 1 0 24 3 0 5 2 0 11 0 0 26 0 6 12 8 0 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 381 H e 21.5 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 1:dsRNA strand1:p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 MG BU3 4 0 7 0 2 4 57 0 0 0 0 0 0 0 0 0 5 0 0 21 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 382 P H b 17.1 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30 MG 29 0 0 0 0 0 0 0 0 0 0 0 58 0 0 3 0 10 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 383 Y H b 0.0 8dvs_A 10 0 0 0 2 2 0 3 4 0 0 0 0 0 0 0 5 0 0 74 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 384 N H b 5.5 8dvs_A 30 5 0 0 0 0 1 0 0 4 0 24 0 0 17 5 7 7 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 385 M H e 36.7 8dvs_A 0 3 0 18 2 5 0 0 11 8 5 8 0 7 25 2 2 5 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 386 I H b 0.0 8dvs_A 0 0 0 0 0 0 0 55 0 6 5 0 5 0 2 0 0 27 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 387 M H b 0.0 8dvs_A 4 0 0 0 1 0 0 15 1 7 52 0 0 0 0 0 0 20 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 388 F H b 17.7 8dvs_A 1 0 1 1 13 1 0 6 22 10 0 3 1 5 11 11 4 6 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 389 N H e 31.5 8dvs_A 6 0 19 23 1 1 4 1 9 1 0 9 1 3 11 4 3 3 0 2 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 390 Y H b 3.9 8dvs_A 1 0 1 1 34 1 2 4 7 3 0 1 1 1 6 7 1 2 0 28 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 391 L H b 3.4 8dvs_A 3 0 1 1 0 1 2 7 3 17 9 1 1 0 6 6 3 1 2 36 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 392 D H e 35.2 8dvs_A 4 0 15 7 6 1 21 1 7 2 2 9 6 1 5 1 2 6 0 2 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 393 Q H b 16.3 8dvs_A 5 0 1 4 1 1 4 1 8 3 0 1 9 16 17 21 4 1 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 394 K H e 36.3 8dvs_A 6 0 1 6 4 1 4 2 32 4 2 2 1 4 9 4 9 3 0 6 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 395 L T e 28.7 8dvs_A 2 1 1 3 12 2 2 7 5 42 6 1 1 3 1 4 3 2 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 396 G T e 67.9 8dvs_A 14 7 3 8 1 11 1 2 10 11 1 8 2 4 4 7 3 2 0 2 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 397 G S e 90.5 8dvs_A 10 1 3 13 2 13 1 1 10 10 1 5 2 1 7 9 7 4 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 398 S e 89.1 8dvs_A 5 0 9 3 1 8 2 1 9 7 0 4 5 3 4 25 8 4 0 2 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 399 S e 39.1 8dvs_A 17 7 4 3 2 4 6 1 6 2 0 2 7 6 5 17 3 3 0 4 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 400 G e 46.4 8dvs_A 5 1 7 8 4 14 1 3 3 5 1 10 7 5 3 7 12 3 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 401 P S e 75.2 8dvs_A 5 0 1 6 1 2 2 1 14 2 1 2 34 5 2 13 4 1 2 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 402 L b 19.7 8dvs_A GOL 4 7 1 1 2 8 2 3 5 24 0 2 1 1 15 1 1 18 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 403 P b 3.9 8dvs_A GOL 5 3 1 1 3 1 0 1 1 1 4 1 69 2 1 6 1 1 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 404 Q E b 10.2 8dvs_A GOL 3 1 4 0 0 1 5 0 7 0 0 0 0 19 51 5 3 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 405 V E b 0.0 8dvs_A 0 0 0 0 0 0 0 58 0 10 0 0 0 0 0 0 0 31 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 406 I b 0.0 8dvs_A 0 0 0 5 27 0 0 6 0 49 3 0 0 0 0 0 0 8 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 407 G b 0.0 8dvs_A 14 0 0 0 0 84 0 0 0 0 0 0 0 0 0 1 0 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 408 L B b 1.7 8dvs_A ETF:BU3 0 0 0 0 0 0 0 0 0 68 25 0 0 0 2 0 0 5 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 409 T B b 0.6 8dvs_A ETF:BU3 0 0 0 0 0 0 0 2 0 0 0 0 0 3 0 14 81 0 0 0 MUTAGEN:/note="TAS->AAA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding":MUTAGEN:/note="TAS->AAA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding" 410 A S b 12.5 8dvs_A BEF:ETF:ALF 92 0 2 2 0 2 0 0 0 0 2 0 0 0 0 0 0 0 0 0 MUTAGEN:/note="TAS->AAA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding":MUTAGEN:/note="TAS->AAA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding" 411 S b 3.1 8dvs_A 0 0 0 2 0 0 0 0 0 0 0 2 0 0 0 68 23 6 0 0 MUTAGEN:/note="TAS->AAA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding":MUTAGEN:/note="TAS->AAA: Loss of dsRNA-induced ATPase activity. No effect on ds-RNA binding. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase ATP-binding" 412 V b 3.3 8dvs_A 4 0 3 1 0 1 0 15 0 7 0 0 50 0 0 2 0 15 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 413 G b 0.0 8dvs_A 5 0 2 0 3 40 0 7 0 5 0 9 4 0 0 1 3 18 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 414 V b 0.0 8dvs_A 5 0 6 1 1 2 0 10 6 14 2 7 3 1 1 3 13 22 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 415 G S e 44.0 8dvs_A p3dsRNA24a 8 3 3 1 1 25 0 4 13 4 0 1 1 3 4 17 8 3 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 416 D S e 77.8 8dvs_A p3SLR30 DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[61.. 5 0 28 4 1 13 2 4 16 2 0 1 4 1 3 8 5 4 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 417 A b 3.6 8dvs_A 24 5 3 1 1 11 0 10 6 6 2 3 4 1 5 1 7 11 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 418 K e 67.0 8dvs_A OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR30 DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Antiviral innate immune response receptor RIG-I[65..:Antiviral innate immune response receptor RIG-I[61..:Antiviral innate immune response receptor RIG-I[64..:Antiviral innate immune response receptor RIG-I[63.. 1 0 11 10 1 4 0 1 25 3 0 1 1 2 11 18 6 3 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 419 N S e 38.8 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Antiviral innate immune response receptor RIG-I[61..:Antiviral innate immune response receptor RIG-I[64..:Antiviral innate immune response receptor RIG-I[63.. 6 0 4 5 2 6 0 4 12 1 1 12 4 5 8 15 10 3 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 420 T H e 21.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Antiviral innate immune response receptor RIG-I[64..:Antiviral innate immune response receptor RIG-I[63.. 5 2 1 1 0 2 2 7 7 25 3 0 3 10 1 4 15 10 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 421 D H e 65.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa] 6 2 13 36 1 4 2 1 1 1 2 1 1 12 2 10 3 3 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 422 E H e 42.7 8dvs_A 4 0 8 29 0 5 2 4 6 1 0 9 0 11 0 18 2 0 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 423 A H b 0.0 8dvs_A 19 6 7 2 0 2 2 4 10 5 0 8 0 0 0 8 7 17 0 2 DOMAIN:/note="Helicase ATP-binding":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase ATP-binding" 424 L H b 8.4 8dvs_A 5 0 1 6 0 1 0 21 1 33 12 0 1 0 2 1 2 9 2 2 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 425 D H e 60.5 8dvs_A 4 0 30 24 0 1 0 5 4 4 0 6 1 10 1 4 3 1 0 0 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 426 Y H e 23.5 8dvs_A 17 0 1 1 1 5 14 5 14 1 0 4 1 7 3 8 2 3 0 11 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 427 I H b 0.0 8dvs_A 8 0 1 1 3 1 0 37 1 12 0 1 1 1 1 3 3 25 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 428 C H b 0.0 8dvs_A 3 19 1 8 1 1 2 5 4 12 3 1 1 10 10 9 9 1 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 429 K H e 45.8 8dvs_A 6 0 1 15 1 1 4 1 23 2 1 15 1 8 15 1 2 1 0 1 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 430 L H b 4.5 8dvs_A 2 2 1 3 1 2 1 11 1 44 1 3 1 1 1 7 3 13 0 3 DOMAIN:/note="Helicase ATP-binding":DOMAIN:/note="Helicase ATP-binding" 431 C H b 2.0 8dvs_A 2 20 1 26 1 2 1 10 1 10 1 1 4 4 3 2 3 8 0 1 432 A H b 2.7 8dvs_A 21 0 8 12 1 1 2 3 5 4 2 7 3 1 2 10 13 5 0 1 433 S H b 14.1 8dvs_A 10 0 1 1 2 6 0 1 5 13 0 21 1 1 7 19 10 1 0 0 434 L H b 0.0 8dvs_A 1 0 1 3 1 1 4 3 4 59 5 3 1 1 3 1 5 1 3 0 435 D T b 11.1 8dvs_A 1 0 50 4 1 4 6 1 1 9 0 8 4 1 4 1 3 1 0 0 436 A b 1.8 8dvs_A 19 0 1 6 1 4 3 13 1 2 1 7 1 3 3 15 16 2 0 1 437 S b 10.9 8dvs_A 6 3 3 13 4 1 0 1 10 6 0 1 3 1 8 34 1 1 3 1 438 V B b 16.0 8dvs_A 1 3 1 7 0 1 5 20 5 9 0 3 3 5 5 1 7 25 0 0 439 I b 8.2 8dvs_A 10 10 6 1 0 1 2 37 1 4 4 0 1 0 1 1 1 17 0 5 440 A b 4.5 8dvs_A 15 4 1 15 0 3 0 1 9 1 7 1 1 3 7 3 16 11 0 2 441 T e 20.1 8dvs_A 0 2 0 3 0 2 0 9 4 2 0 4 2 5 0 10 49 5 0 0 442 V b 10.7 8dvs_A 5 0 3 0 5 1 2 11 0 3 0 0 27 0 14 10 0 13 0 4 443 K e 42.0 8dvs_A 1 0 2 7 0 1 0 0 22 1 0 0 4 8 14 12 20 5 0 3 444 H T e 77.0 8dvs_A 6 0 4 16 1 1 13 11 1 9 2 8 2 5 5 8 1 6 0 3 445 N T e 25.5 8dvs_A 2 5 16 5 0 1 17 0 0 1 0 19 0 11 8 3 6 2 0 2 446 L H e 41.6 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa] 1 3 4 3 3 3 0 1 3 23 2 5 1 1 27 10 1 5 0 5 447 E H e 65.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 7 0 4 29 0 3 0 3 7 6 0 1 8 7 10 8 2 3 0 0 448 E H e 26.1 8dvs_A 3 0 12 36 0 1 2 2 1 6 0 3 3 15 1 12 4 1 0 0 449 L H b 7.3 8dvs_A 0 0 3 0 3 0 0 17 2 57 4 2 0 0 0 5 0 5 0 0 450 E T e 58.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 0 0 11 20 4 0 2 0 12 14 2 0 2 4 19 7 2 1 0 0 451 Q T e 65.8 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa] 6 0 4 18 2 2 2 4 11 0 2 4 5 21 4 6 6 2 0 0 452 V T e 20.7 8dvs_A 0 2 0 0 8 0 14 17 0 2 2 2 2 4 2 4 0 24 0 17 453 V S b 12.7 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa] 3 2 0 0 0 4 0 12 0 11 0 2 0 0 2 4 10 48 0 0 454 Y e 46.1 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa] 9 0 0 0 2 0 18 0 2 5 0 7 10 6 3 8 8 5 0 16 455 K e 64.2 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 3 2 0 8 0 2 0 3 16 0 10 2 2 5 26 14 2 6 0 0 456 P b 7.8 8dvs_A ETF 2 0 0 0 4 0 2 0 5 5 2 0 65 0 4 0 3 5 0 2 457 Q B e 54.1 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 0 9 5 20 0 2 7 0 12 5 0 12 0 11 4 5 2 4 0 3 458 K b 17.9 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] ETF 1 0 3 21 0 1 0 7 21 11 6 0 7 4 5 1 4 7 0 0 459 F e 37.3 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[178 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 1 0 4 7 10 1 3 11 11 11 7 0 1 7 4 2 7 4 4 5 460 F E e 32.1 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 0 2 3 0 18 2 0 10 2 8 2 0 5 0 2 8 2 17 3 16 461 R E e 27.3 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[171 aa]:E3 ubiquitin-protein ligase RNF135[169 aa]:E3 ubiquitin-protein ligase RNF135[178 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 6 0 5 7 2 5 0 6 14 5 0 5 2 8 21 1 5 6 0 3 462 K E e 40.1 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[178 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[638 aa]:Antiviral innate immune response receptor RIG-I[64.. 3 0 3 10 0 3 0 6 18 8 0 7 14 5 5 9 4 1 0 5 463 V b 13.3 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[178 aa] 7 7 0 0 2 0 0 20 0 12 3 0 3 0 0 7 3 21 0 13 464 E e 68.3 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[171 aa]:E3 ubiquitin-protein ligase RNF135[169 aa]:E3 ubiquitin-protein ligase RNF135[178 aa] 4 2 17 22 0 4 5 3 8 1 0 2 3 11 6 2 0 0 2 8 465 S e 43.8 8dvs_A 12 0 6 8 1 1 0 5 6 5 0 5 6 1 8 20 7 8 0 0 466 R b 12.6 8dvs_A 10 0 4 3 0 5 0 1 6 3 7 3 5 2 28 6 10 1 0 4 467 I S e 98.2 8dvs_A 3 0 2 1 3 7 0 15 1 30 0 0 3 0 5 6 6 15 0 3 468 S e 43.8 8dvs_A 1 0 2 12 3 3 0 3 0 11 4 0 7 8 5 23 15 3 0 0 469 D e 29.6 8dvs_A 0 0 33 19 3 0 2 0 2 4 0 9 4 3 6 6 4 3 0 0 470 K H e 47.2 8dvs_A 5 0 4 19 0 2 0 4 13 7 0 0 17 7 4 12 2 3 0 0 471 F H b 0.0 8dvs_A 3 0 0 1 33 2 0 6 0 29 5 0 2 0 0 5 4 1 3 3 472 K H e 41.5 8dvs_A 8 3 3 11 0 10 0 2 18 1 4 3 4 5 5 14 7 2 0 0 473 Y H e 68.7 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[64.. 3 4 5 6 3 5 0 3 7 6 2 6 6 4 7 8 12 7 0 6 474 I H b 1.8 8dvs_A 9 2 4 3 2 0 0 22 4 21 3 3 3 2 2 0 12 0 0 6 475 I H b 0.0 8dvs_A 5 3 0 3 3 7 0 17 0 40 6 5 0 3 0 3 0 1 2 2 476 A H b 8.0 8dvs_A 14 0 2 10 0 6 3 1 13 7 0 5 1 5 5 9 3 10 0 6 477 Q H e 30.1 8dvs_A 5 0 3 7 0 4 0 1 11 5 0 8 14 22 8 3 5 1 0 3 478 L H b 0.0 8dvs_A 3 0 1 1 2 3 3 7 3 54 8 3 4 0 1 1 1 1 2 3 479 M H b 0.0 8dvs_A 1 0 3 3 0 6 5 16 3 10 22 1 1 6 1 5 4 6 0 7 480 R H e 46.2 8dvs_A 4 0 8 6 1 1 6 3 19 4 2 1 1 11 21 4 6 1 0 1 481 D H e 27.8 8dvs_A 14 0 16 15 6 5 3 6 6 2 0 3 4 5 7 3 3 1 0 1 482 T H b 0.0 8dvs_A 6 0 3 4 3 1 0 9 3 18 0 11 5 1 1 13 10 4 5 3 483 E H b 8.5 8dvs_A 3 0 5 30 3 3 0 0 12 6 2 0 3 11 8 6 1 1 2 3 484 S H e 56.2 8dvs_A 11 3 6 1 0 9 0 1 2 4 0 10 9 3 3 19 11 3 0 4 485 L H b 10.1 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 1 0 6 1 10 4 0 2 6 35 0 3 3 3 1 4 7 4 0 10 486 A H b 1.8 8dvs_A 20 4 4 1 3 1 3 1 10 4 0 8 1 4 6 9 3 13 3 3 487 K H e 39.2 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa] 12 0 7 6 1 1 0 7 20 1 0 5 1 8 14 7 3 1 0 5 488 R H e 65.6 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] SO4 1 0 14 1 1 6 0 1 9 2 3 3 3 9 21 14 1 1 0 7 489 I H e 30.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 1 0 3 1 10 1 0 24 6 18 3 4 1 1 1 6 1 12 4 1 490 C b 8.7 8dvs_A 9 6 3 1 3 8 5 7 1 10 0 1 3 4 5 15 4 10 0 5 491 K T e 77.8 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 1 0 3 16 1 7 0 1 37 4 2 6 3 3 10 1 1 4 0 0 492 D T e 54.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa] 1 0 36 4 1 5 5 3 7 4 0 4 1 12 6 8 1 1 0 0 493 L b 2.2 8dvs_A 7 0 4 1 4 1 0 9 1 39 0 1 17 1 1 3 6 4 0 0 494 E T e 37.7 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa]:Antiviral innate immune response receptor RIG-I[61..:Antiviral innate immune response receptor RIG-I[64.. 1 0 11 21 6 7 3 0 12 3 8 0 6 0 3 3 7 1 0 6 495 N T e 80.0 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa]:Antiviral innate immune response receptor RIG-I[61.. 6 0 14 3 0 2 3 3 11 1 2 15 1 4 7 11 5 9 0 4 MOD_RES:/note="(Microbial infection) Deamidated asparagine; by herpes simplex virus 1/HHV-1 UL37":MUTAGEN:/note="N->Q: Complete loss of herpes simplex virus 1 UL37- mediated deamidation; when associated with Q-549.":MOD_RES:/note="(Microbial infection) Deamidated asparagine; by herpes simplex virus 1/HHV-1 UL37":MUTAGEN:/note="N->Q: Complete loss of herpes simplex virus 1 UL37- mediated deamidation; when associated with Q-549." 496 L S e 24.2 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa] 0 0 4 0 11 3 0 24 3 34 4 0 3 0 0 0 3 5 0 3 497 S S b 13.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa] 6 0 0 1 9 6 5 3 4 7 0 3 5 11 3 9 20 1 3 3 498 Q e 90.3 8dvs_A RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 1:p2dsRNA:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR30 DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa]:Antiviral innate immune response receptor RIG-I[61..:Antiviral innate immune response receptor RIG-I[64.. 3 0 1 8 4 1 0 6 19 8 0 1 6 12 10 4 3 9 4 1 499 I b 18.7 8dvs_A RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa]:Antiviral innate immune response receptor RIG-I[64.. 7 0 1 4 1 1 2 17 4 23 8 8 1 1 1 1 4 12 0 7 500 Q e 76.5 8dvs_A RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:p3dsRNAa:p1dsRNA:OHdsRNA:p3SLR30:p3dsRNA24a DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Antiviral innate immune response receptor RIG-I[61..:Antiviral innate immune response receptor RIG-I[64.. 10 0 1 9 1 12 6 1 1 9 2 4 1 20 9 11 1 1 0 1 501 N S e 75.8 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa]:Antiviral innate immune response receptor RIG-I[65..:Antiviral innate immune response receptor RIG-I[61..:Antiviral innate immune response receptor RIG-I[64.. 16 3 4 5 1 4 0 1 9 4 4 14 1 3 14 9 4 1 0 1 502 R b 17.8 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa]:Antiviral innate immune response receptor RIG-I[64.. 4 0 1 4 1 2 3 7 13 7 0 3 1 1 26 20 4 1 0 1 503 E e 62.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Antiviral innate immune response receptor RIG-I[64.. 10 3 14 21 0 1 0 3 3 5 0 5 8 5 7 6 8 0 0 0 504 F T b 13.4 8dvs_A 0 0 0 3 29 0 0 3 0 25 5 3 3 8 3 3 0 0 0 13 505 G T b 6.0 8dvs_A 6 6 5 0 5 48 0 6 3 1 0 5 0 3 0 5 2 0 0 3 506 T S e 33.1 8dvs_A SO4 1 0 6 1 0 7 0 7 9 9 0 5 1 0 12 8 32 1 0 0 507 Q H e 74.5 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 1:p3dsRNAa:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 SO4 1 0 6 4 0 6 0 1 20 12 0 1 1 27 2 4 2 1 6 6 508 K H e 54.7 8dvs_A RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 1:dsRNA strand1:p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[61.. SO4 17 6 3 11 3 1 2 1 11 1 5 8 3 4 12 6 5 1 0 0 509 Y H b 0.0 8dvs_A 7 0 1 3 7 1 3 1 1 24 0 1 8 1 8 9 1 3 0 21 510 E H e 21.6 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3SLR14 BU3 1 0 9 16 0 12 6 1 6 4 0 3 4 12 12 9 3 1 0 0 511 Q H e 56.6 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:dsRNA strand1:p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 3 0 6 4 0 4 0 7 8 4 0 1 6 34 11 10 1 1 0 0 512 W H b 0.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa] 10 0 1 1 6 1 3 1 4 9 5 3 1 8 3 4 1 4 33 1 513 I H b 0.6 8dvs_A 12 3 1 2 1 2 2 20 6 10 13 7 1 1 1 2 4 6 4 1 514 V H e 22.7 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa] 10 0 1 1 1 3 2 12 1 19 6 1 1 3 3 2 4 28 0 1 515 T H e 27.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa] 8 0 1 1 5 10 0 4 12 5 0 3 1 7 3 23 15 3 0 0 516 V H b 1.3 8dvs_A 16 3 8 1 3 4 0 6 3 16 13 1 1 1 3 1 3 17 0 0 517 Q H b 15.3 8dvs_A 12 5 10 18 3 4 2 1 4 13 0 1 1 12 6 5 1 1 0 1 518 K H e 49.1 8dvs_A RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa] 7 0 9 10 3 9 0 1 30 1 0 4 3 6 7 4 4 1 0 0 519 A H e 25.0 8dvs_A 19 0 7 3 6 10 0 3 5 1 3 1 1 3 8 15 3 3 0 7 520 C H b 6.7 8dvs_A 18 18 3 3 0 1 0 12 1 6 0 8 1 1 5 7 3 9 0 3 521 M H b 7.7 8dvs_A 16 0 1 3 7 1 9 6 4 6 10 1 4 4 7 4 9 5 0 3 522 V T e 36.7 8dvs_A 4 6 1 18 1 1 6 9 1 12 0 4 1 3 5 10 9 6 0 3 523 F e 36.8 8dvs_A 6 0 1 1 34 1 0 4 4 22 0 3 4 4 1 4 1 1 3 7 524 Q e 41.3 8dvs_A 7 3 7 5 1 21 0 1 11 7 0 1 1 15 3 9 1 1 0 5 525 M e 24.6 8dvs_A 8 0 1 1 3 4 5 5 1 29 14 4 1 1 4 4 4 3 4 3 526 P T e 106.2 8dvs_A 6 1 4 4 4 9 1 4 19 2 1 4 14 3 5 5 2 4 3 5 527 D T e 56.2 8dvs_A 13 6 17 6 7 11 3 1 3 3 1 1 2 4 5 2 2 8 0 6 528 K S e 55.7 8dvs_A 9 0 1 6 1 11 0 1 19 9 4 4 3 6 7 8 1 5 3 1 529 D S e 75.9 8dvs_A 4 0 27 5 3 7 0 1 6 7 2 5 1 5 4 8 6 7 0 1 530 E H e 36.7 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 9 0 1 30 0 3 0 1 10 10 0 8 3 5 8 1 3 4 3 0 531 E H b 3.0 8dvs_A 11 0 3 20 0 1 0 0 7 17 3 7 0 8 6 9 3 1 0 3 532 S H e 21.1 8dvs_A 3 0 5 2 0 10 0 11 3 9 3 0 0 12 4 23 7 1 3 3 533 R H e 47.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 1 0 1 11 8 7 4 1 8 7 8 5 1 0 29 6 1 1 0 3 534 I H b 10.5 8dvs_A 1 0 0 1 3 9 0 25 3 15 3 0 0 0 3 4 8 13 8 3 535 C H b 6.0 8dvs_A 4 32 0 3 6 3 0 3 3 3 3 7 0 3 0 0 4 19 2 3 536 K H b 10.4 8dvs_A 6 0 1 6 6 1 6 7 17 12 3 4 1 1 13 5 3 8 0 1 537 A H b 4.5 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 22 0 13 12 1 4 0 4 7 5 3 1 1 1 5 13 7 1 0 1 538 L H b 2.2 8dvs_A 6 0 4 6 1 1 3 3 1 31 4 3 1 7 4 12 1 6 0 5 539 F H b 15.8 8dvs_A 2 0 4 4 16 10 1 4 7 18 6 4 1 1 3 2 6 2 2 8 540 L H b 3.4 8dvs_A 14 0 1 10 8 4 0 13 4 17 0 1 3 8 1 9 1 1 0 1 541 Y H b 7.0 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 7 0 1 4 8 1 10 5 4 4 6 2 1 3 1 10 4 1 6 21 542 T H b 2.6 8dvs_A 26 3 4 8 3 4 0 1 3 9 5 3 1 6 8 1 9 4 0 3 543 S H e 22.7 8dvs_A 9 5 1 12 1 4 0 8 9 5 0 1 1 3 6 20 6 6 0 3 544 H H b 0.5 8dvs_A 1 0 11 15 1 6 29 3 3 4 0 2 4 1 1 6 3 1 5 3 545 L H b 1.1 8dvs_A 5 0 0 1 3 2 0 17 3 48 3 0 0 0 0 6 2 3 0 4 546 R H e 33.2 8dvs_A RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 BU3 6 3 1 1 1 4 0 1 8 9 7 1 1 3 36 4 4 4 0 6 547 K H e 24.5 8dvs_A 8 0 13 6 1 4 0 8 28 1 0 1 1 1 9 9 1 6 0 3 548 Y H b 1.3 8dvs_A 3 0 3 1 5 6 4 1 1 10 0 1 1 6 1 6 3 11 5 33 549 N H b 0.0 8dvs_A 8 0 1 10 1 1 8 1 2 6 3 22 1 3 6 11 3 12 0 0 MOD_RES:/note="(Microbial infection) Deamidated asparagine; by herpes simplex virus 1/HHV-1 UL37":MUTAGEN:/note="N->Q: Complete loss of herpes simplex virus 1 UL37- mediated deamidation; when associated with Q-495.":MOD_RES:/note="(Microbial infection) Deamidated asparagine; by herpes simplex virus 1/HHV-1 UL37":MUTAGEN:/note="N->Q: Complete loss of herpes simplex virus 1 UL37- mediated deamidation; when associated with Q-495." 550 D H b 16.7 8dvs_A BU3 8 0 33 11 1 9 4 1 6 6 0 4 1 1 4 1 7 3 0 0 551 A H b 0.0 8dvs_A 31 6 6 6 1 10 0 13 3 4 0 4 1 1 1 9 3 3 0 0 552 L H b 4.5 8dvs_A 3 3 1 6 7 2 3 5 4 29 5 1 3 4 4 1 9 4 3 3 553 I H e 26.3 8dvs_A 2 0 6 4 8 1 3 9 6 23 3 1 9 5 1 1 10 8 0 1 554 I H b 9.4 8dvs_A BU3 4 3 3 3 10 1 0 24 1 16 0 1 3 1 3 3 6 11 5 0 555 S H b 0.8 8dvs_A 4 4 11 3 3 11 7 1 5 4 0 6 1 3 4 17 4 3 0 8 556 E H e 38.7 8dvs_A 6 0 20 25 3 1 0 1 1 3 0 6 1 6 14 9 1 1 3 0 557 H H b 14.7 8dvs_A 7 0 6 9 1 4 17 2 10 6 3 1 1 3 3 8 9 1 2 8 558 A S b 0.9 8dvs_A 29 0 3 3 1 14 8 16 1 4 0 3 1 3 1 1 3 8 0 0 559 R b 15.8 8dvs_A 4 0 6 6 0 7 3 1 6 5 3 1 1 2 39 9 1 1 0 6 560 M H b 2.9 8dvs_A 14 0 3 7 3 1 4 13 6 17 14 3 4 1 1 3 3 3 0 0 561 K H e 44.8 8dvs_A 1 3 3 5 3 1 0 5 26 7 3 6 3 1 14 4 5 6 3 0 562 D H b 7.4 8dvs_A 5 0 23 10 4 7 3 3 3 7 0 6 6 4 8 4 1 4 0 1 563 A H b 0.0 8dvs_A 41 0 3 10 5 1 7 5 1 9 0 1 1 1 1 3 6 5 0 0 564 L H b 2.2 8dvs_A 4 0 3 1 0 5 0 3 8 28 5 1 1 1 10 7 9 7 0 9 565 D H e 41.4 8dvs_A 5 0 21 11 1 8 0 3 1 8 0 15 3 4 1 11 3 1 0 3 566 Y H e 30.9 8dvs_A BU3 5 0 3 7 10 1 8 4 9 4 5 5 1 1 7 1 4 1 0 24 567 L H b 0.0 8dvs_A 6 0 1 1 3 4 0 4 1 54 0 3 0 0 5 3 1 14 0 0 568 K H e 35.8 8dvs_A 2 0 0 24 0 0 0 0 21 10 0 0 0 13 6 13 3 6 0 0 569 D H e 54.3 8dvs_A 4 2 23 9 0 8 9 0 3 1 0 12 0 2 10 9 4 1 0 0 570 F H b 13.4 8dvs_A 6 0 1 3 38 1 2 1 6 4 2 4 1 0 1 4 10 1 2 14 571 F H b 4.8 8dvs_A 4 3 5 1 14 4 0 1 4 21 5 1 1 6 4 6 1 10 0 11 572 S H e 50.0 8dvs_A 4 0 7 4 1 3 4 1 4 6 3 9 5 3 3 36 6 1 0 1 573 N H e 60.0 8dvs_A 6 0 14 13 1 4 5 1 9 2 0 20 1 3 5 10 1 1 0 3 574 V H b 9.3 8dvs_A 6 0 5 7 1 8 0 16 1 10 5 1 1 3 1 1 14 18 0 1 575 R H e 50.2 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 5 0 13 8 1 8 3 1 7 4 4 4 10 1 16 10 3 1 0 1 576 A H e 80.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 15 0 5 11 6 8 4 1 8 6 3 5 1 3 6 7 5 6 0 1 577 A S e 44.6 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 22 0 1 6 1 7 3 1 9 5 0 9 3 7 1 6 5 10 3 1 578 G e 33.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa] 8 0 5 2 6 19 1 1 13 5 1 7 4 3 4 12 5 2 0 1 579 F e 29.2 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa] 4 1 1 2 20 8 4 5 2 17 3 1 1 3 1 5 9 2 6 4 580 D e 24.1 8dvs_A 8 0 24 10 4 8 1 1 6 6 3 3 1 6 4 6 5 2 0 1 D->E:LB/B:rs1721728: -; 581 E H e 63.8 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa] 5 2 16 31 1 3 0 5 7 4 2 1 1 1 9 8 1 1 0 3 DISORDER:predicted by DISOPRED 582 I H b 18.7 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 11 0 5 1 1 3 0 19 3 9 0 1 7 1 3 3 16 9 0 7 DISORDER:predicted by DISOPRED 583 E H b 8.0 8dvs_A 1 0 3 38 1 1 0 5 6 4 0 3 7 15 2 6 5 1 0 3 DISORDER:predicted by DISOPRED 584 Q H e 52.6 8dvs_A 5 0 2 17 0 1 5 2 8 6 8 1 3 15 12 5 1 3 0 5 DISORDER:predicted by DISOPRED 585 D H e 21.0 8dvs_A 10 0 16 6 2 4 0 6 5 10 0 11 3 10 5 7 3 1 0 0 DISORDER:predicted by DISOPRED 586 L H b 0.6 8dvs_A 3 0 1 4 7 1 2 13 5 40 4 1 2 0 2 1 1 6 0 6 DISORDER:predicted by DISOPRED 587 T H b 3.2 8dvs_A 5 0 3 4 0 4 0 1 1 12 2 8 7 5 1 13 18 16 0 0 DISORDER:predicted by DISOPRED 588 Q H e 43.4 8dvs_A 5 0 9 3 2 1 5 6 15 6 0 5 4 22 4 6 1 4 0 0 DISORDER:predicted by DISOPRED 589 R H b 17.8 8dvs_A 3 0 5 1 4 4 2 3 5 10 3 3 4 5 32 9 1 4 0 1 590 F H b 1.9 8dvs_A 5 0 5 3 34 3 3 4 1 4 6 4 3 1 1 4 1 6 2 8 DISORDER:predicted by DISOPRED 591 E H e 49.2 8dvs_A 4 2 7 14 3 9 3 5 10 7 1 1 1 3 7 13 7 2 0 1 592 E H e 59.3 8dvs_A 2 0 10 23 5 2 4 1 10 8 2 4 5 7 1 8 3 2 0 1 DISORDER:predicted by DISOPRED 593 K H e 28.3 8dvs_A 7 0 1 1 2 6 4 1 25 16 0 7 4 1 7 5 7 1 0 3 DISORDER:predicted by DISOPRED 594 L H b 18.5 8dvs_A 3 0 1 1 8 1 0 17 6 32 7 1 3 1 1 4 1 12 0 0 DISORDER:predicted by DISOPRED 595 Q H e 79.6 8dvs_A 1 0 7 11 1 6 5 1 8 1 5 12 6 12 8 8 1 5 3 0 DISORDER:predicted by DISOPRED 596 E H e 51.8 8dvs_A 3 0 10 22 1 5 13 3 10 5 6 1 1 3 1 8 3 6 0 0 DISORDER:predicted by DISOPRED 597 L H b 0.0 8dvs_A 8 0 3 1 3 1 2 15 1 41 2 0 1 3 1 6 1 14 0 0 DISORDER:predicted by DISOPRED 598 E H e 29.1 8dvs_A 5 0 3 20 0 3 4 9 11 1 6 3 7 11 5 6 1 3 0 0 DISORDER:predicted by DISOPRED 599 S H e 53.1 8dvs_A 3 0 9 3 4 3 2 5 7 7 0 13 11 5 2 17 3 6 0 0 DISORDER:predicted by DISOPRED 600 V H b 9.3 8dvs_A 10 3 1 3 8 6 3 9 3 21 0 0 3 0 1 9 1 11 6 3 DISORDER:predicted by DISOPRED 601 S H b 14.8 8dvs_A 19 3 1 1 1 1 3 3 7 13 0 3 5 1 1 26 7 3 0 5 DISORDER:predicted by DISOPRED 602 R H e 59.7 8dvs_A 3 0 1 9 3 6 0 3 11 4 3 4 5 3 10 5 8 17 2 1 DISORDER:predicted by DISOPRED 603 D e 39.5 8dvs_A 11 0 23 10 1 5 2 3 4 2 0 21 3 1 1 8 1 1 0 4 604 P G e 89.9 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[178 aa] 7 0 3 4 4 5 0 1 3 7 0 0 48 2 1 7 1 5 0 0 605 S G e 72.7 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[169 aa]:E3 ubiquitin-protein ligase RNF135[178 aa] 15 0 10 14 2 13 0 3 7 6 0 2 2 0 1 16 6 1 0 0 606 N G b 7.9 8dvs_A 5 0 12 10 8 3 0 3 14 7 2 10 4 6 1 3 3 5 0 4 607 E e 30.2 8dvs_A 1 0 1 22 0 15 4 4 8 14 2 3 1 3 3 3 9 7 0 0 608 N b 0.6 8dvs_A 1 0 8 4 2 1 22 1 1 3 0 16 3 0 4 27 6 1 0 0 609 P H e 27.1 8dvs_A 2 0 2 8 0 2 0 2 0 3 3 0 60 0 0 11 0 0 4 0 610 K H b 0.5 8dvs_A 0 0 0 9 0 2 4 0 77 0 0 0 0 2 2 0 2 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 611 L H b 0.6 8dvs_A 1 0 1 1 12 1 0 3 2 51 2 0 1 0 1 1 2 19 0 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 612 E H e 54.3 8dvs_A 2 0 0 31 2 3 2 3 6 1 5 4 0 14 8 7 8 0 0 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 613 D H e 22.2 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[178 aa] 9 3 13 2 0 0 6 0 25 4 4 0 4 0 3 5 11 2 0 7 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 614 L H b 0.0 8dvs_A 0 0 0 3 0 0 0 4 2 74 5 0 0 0 4 0 0 7 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 615 C H b 4.7 8dvs_A 0 22 0 6 0 0 2 16 5 16 0 0 0 5 11 5 0 9 0 1 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 616 F H e 47.8 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[171 aa]:E3 ubiquitin-protein ligase RNF135[169 aa]:E3 ubiquitin-protein ligase RNF135[178 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 1 0 5 12 7 2 5 3 8 4 5 10 0 14 9 6 2 1 0 5 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 617 I H b 0.6 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[171 aa]:E3 ubiquitin-protein ligase RNF135[169 aa]:E3 ubiquitin-protein ligase RNF135[178 aa] 4 3 0 6 10 1 0 27 5 11 2 2 0 0 0 1 7 19 2 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 618 L H b 0.0 8dvs_A 1 0 0 6 7 1 0 6 1 59 0 0 0 4 0 1 1 13 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 619 Q H e 31.6 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[171 aa]:E3 ubiquitin-protein ligase RNF135[178 aa] 6 0 9 5 0 2 2 4 8 16 4 2 1 10 9 6 4 10 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 620 E H e 38.2 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[171 aa]:E3 ubiquitin-protein ligase RNF135[169 aa]:E3 ubiquitin-protein ligase RNF135[178 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 2 0 11 26 0 3 0 4 19 5 0 10 1 2 2 9 1 3 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 621 E H b 6.0 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[171 aa]:E3 ubiquitin-protein ligase RNF135[169 aa]:E3 ubiquitin-protein ligase RNF135[178 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 5 2 2 13 1 1 20 3 1 13 0 4 1 8 4 6 6 4 0 6 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 622 Y H b 5.2 8dvs_A 2 0 2 6 37 6 4 1 2 11 0 2 1 3 1 2 1 1 0 19 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 623 H H e 83.8 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[171 aa]:E3 ubiquitin-protein ligase RNF135[169 aa]:E3 ubiquitin-protein ligase RNF135[178 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 4 0 4 15 4 6 10 4 8 1 6 5 1 8 4 10 7 1 0 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 624 L H e 61.8 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[171 aa]:E3 ubiquitin-protein ligase RNF135[169 aa]:E3 ubiquitin-protein ligase RNF135[178 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 3 0 13 2 0 2 6 6 4 14 1 2 1 7 11 10 7 5 0 5 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 625 N e 40.0 8dvs_A 7 0 14 3 0 5 5 1 2 4 0 15 7 4 5 14 12 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 626 P S e 68.2 8dvs_A 6 0 3 9 3 8 0 1 12 3 0 4 25 3 3 9 9 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 627 E S e 70.9 8dvs_A 6 0 14 33 0 7 5 4 4 2 0 3 1 5 2 10 3 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 628 T b 2.6 8dvs_A 10 0 1 4 11 9 0 2 1 1 2 5 4 2 1 7 37 4 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 629 I b 7.6 8dvs_A 2 2 0 0 3 0 0 8 14 12 0 2 0 3 36 11 0 4 0 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 630 T B b 0.0 8dvs_A 13 22 3 0 0 21 0 9 0 0 0 0 0 0 0 6 15 10 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 631 I b 0.0 8dvs_A 0 0 0 0 0 2 0 51 0 29 9 0 0 0 0 0 0 7 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 632 L b 0.0 8dvs_A 0 2 0 0 0 0 0 52 0 7 0 0 0 0 0 0 2 34 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 633 F E b 0.0 8dvs_A 0 2 0 0 92 0 0 0 0 0 0 0 0 0 3 0 0 0 0 0 MUTAGEN:/note="FVKT->AVKA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="FVKT->AVKA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 634 V E b 0.0 8dvs_A 7 2 0 0 0 0 0 0 0 0 0 0 0 0 0 6 16 68 0 0 MUTAGEN:/note="FVKT->AVKA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="FVKT->AVKA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 635 K S e 68.4 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 SO4 0 0 9 35 0 7 5 0 20 0 0 7 0 8 5 2 2 0 0 0 MUTAGEN:/note="FVKT->AVKA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="FVKT->AVKA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 636 T e 31.8 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 MG BU3 4 0 0 7 9 0 0 1 7 0 0 0 0 17 20 0 26 0 0 8 MUTAGEN:/note="FVKT->AVKA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="FVKT->AVKA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 637 R H e 38.7 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 0 0 0 0 0 0 0 3 13 0 0 0 0 0 77 0 0 4 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 638 A H e 43.8 8dvs_A BU3 18 3 10 3 0 2 3 5 0 0 0 4 0 5 13 2 2 15 1 11 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 639 L H b 5.1 8dvs_A MG 4 0 0 0 0 4 0 10 3 8 6 0 0 0 0 17 41 6 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 640 V H b 0.0 8dvs_A 54 0 0 0 3 0 0 2 0 2 0 0 0 0 0 2 3 30 0 3 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 641 D H e 50.6 8dvs_A 0 0 19 15 1 5 1 3 8 6 3 3 0 3 9 11 3 6 0 5 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 642 A H b 7.1 8dvs_A 16 0 6 10 0 0 0 10 2 13 3 0 0 0 0 8 7 20 3 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 643 L H b 0.6 8dvs_A 0 0 0 0 0 0 0 20 0 64 7 0 0 0 0 0 0 8 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 644 K H e 27.8 8dvs_A 14 3 2 9 1 0 3 0 11 7 2 4 3 4 0 11 22 4 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 645 N H e 44.2 8dvs_A 0 2 13 9 0 0 4 0 7 5 0 16 0 6 24 6 3 0 2 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 646 W H b 2.0 8dvs_A 2 0 0 2 9 0 0 12 3 33 3 0 0 2 0 0 2 8 15 8 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 647 I H b 2.3 8dvs_A 4 0 0 0 12 0 0 19 0 53 6 0 0 0 0 3 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 648 E H e 57.8 8dvs_A 6 0 6 11 3 1 0 1 12 6 2 4 1 10 9 16 7 4 0 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 649 G T e 75.0 8dvs_A 3 0 1 9 1 15 2 7 4 5 0 12 1 10 6 9 9 6 0 1 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 650 N b 17.0 8dvs_A 1 0 7 5 0 3 19 10 0 6 0 13 0 7 8 3 7 3 4 3 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 651 P T e 91.5 8dvs_A 4 0 4 6 0 5 0 2 5 8 0 1 50 3 2 4 2 3 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 652 K T e 61.3 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[171 aa]:E3 ubiquitin-protein ligase RNF135[169 aa]:E3 ubiquitin-protein ligase RNF135[178 aa] 6 3 7 17 2 4 8 1 12 5 2 10 6 2 5 7 4 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 653 L b 1.1 8dvs_A 3 2 2 4 7 3 1 13 2 32 8 3 1 1 2 1 11 3 0 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 654 S e 71.1 8dvs_A 9 0 1 5 1 1 2 1 10 2 0 9 16 3 11 23 1 3 0 1 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 655 F S e 41.6 8dvs_A 3 3 2 1 24 5 10 6 5 5 5 5 1 1 5 6 3 6 0 6 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 656 L b 7.9 8dvs_A 3 0 1 1 9 1 2 24 1 27 0 1 4 1 8 1 1 9 5 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 657 K e 40.6 8dvs_A 4 3 1 2 1 1 0 2 21 2 0 3 1 1 35 9 12 1 0 1 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 658 P B b 11.6 8dvs_A 16 10 1 3 1 4 0 4 1 2 0 1 32 1 1 7 8 7 0 1 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 659 G b 2.4 8dvs_A 10 0 5 2 2 26 7 1 2 1 1 6 1 9 2 16 7 2 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 660 I b 9.4 8dvs_A 5 5 0 0 17 1 3 16 0 6 1 0 0 0 2 5 7 21 0 8 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 661 L B b 0.0 8dvs_A 4 0 0 0 20 2 3 8 2 32 8 0 0 0 2 4 3 6 0 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 662 T b 10.4 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b 7 0 0 1 0 7 0 21 0 3 1 3 0 2 0 9 17 27 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 663 G b 7.1 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p2dsRNA:p3SLR30:OHSLR30 0 0 7 0 0 73 0 4 0 0 2 0 0 3 0 2 3 2 2 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 664 R e 34.0 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30 GTP 7 2 0 0 5 3 17 1 0 2 2 1 2 12 21 16 3 3 2 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 665 G e 45.2 8dvs_A p2dsRNA:p1dsRNA:OHdsRNA:OHSLR30 8 0 0 2 2 36 2 0 0 1 0 11 7 0 3 22 3 3 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 666 K e 52.4 8dvs_A p3SLR30:OHSLR30 BU3:ETF 7 0 11 4 0 7 2 0 13 2 0 11 6 2 13 14 5 0 1 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 667 T T e 47.4 8dvs_A RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30 BU3 10 2 3 8 0 12 0 4 7 0 4 4 0 0 4 20 19 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 668 N T e 34.5 8dvs_A RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30 BU3:ETF 8 0 5 2 0 7 3 3 11 4 0 19 3 4 3 25 0 2 0 1 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 669 Q S e 43.4 8dvs_A ETF 5 0 6 4 0 11 0 6 15 2 0 6 4 22 7 5 2 2 0 1 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 670 N S e 86.1 8dvs_A 3 0 10 6 1 9 7 6 2 3 1 16 2 3 3 21 3 1 0 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 671 T e 28.6 8dvs_A dsRNA strand 1 10 0 3 14 4 7 0 4 10 1 7 4 1 3 2 8 14 5 0 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 672 G S e 41.7 8dvs_A 6 0 9 14 3 35 2 1 3 5 0 5 3 4 1 4 1 2 0 1 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 673 M b 18.4 8dvs_A 1 0 3 2 3 3 2 4 2 16 40 1 1 3 5 5 3 6 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 674 T e 48.7 8dvs_A dsRNA strand 1:p3SLR30:OHSLR30 1 0 6 5 0 2 2 1 4 6 0 16 1 3 2 15 31 4 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 675 L H e 29.2 8dvs_A 2 0 1 1 9 1 5 5 2 14 5 2 4 35 5 2 2 4 0 1 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 676 P H e 76.0 8dvs_A p3SLR30:OHSLR30 DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[668 aa] 2 1 2 7 0 3 1 1 28 1 2 3 8 9 20 6 4 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 677 A H e 33.0 8dvs_A 9 0 5 19 5 3 0 3 7 6 4 2 0 15 9 4 5 2 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 678 Q H b 2.0 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:p2dsRNA:p3SLR30:OHSLR30 0 0 3 0 0 0 0 0 0 0 6 0 0 68 19 2 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 679 K H e 61.3 8dvs_A 0 0 9 15 3 0 0 6 20 12 2 3 2 13 7 2 4 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 680 C H e 56.7 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[65.. 4 6 13 30 2 2 0 3 1 6 0 0 0 8 5 6 5 2 4 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 681 I H b 18.7 8dvs_A 18 0 0 0 2 0 0 18 0 1 0 0 0 0 0 2 28 30 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 682 L H b 12.9 8dvs_A 0 0 0 0 0 0 0 29 0 52 6 0 0 0 0 0 0 14 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 683 D H e 61.1 8dvs_A 3 0 20 19 0 1 2 1 12 1 0 0 0 12 14 11 2 3 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 684 A T b 17.9 8dvs_A 6 0 11 6 0 2 0 0 31 7 1 3 0 12 11 7 2 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 685 F b 1.4 8dvs_A 0 0 0 0 94 0 0 0 0 2 0 0 0 0 0 0 0 5 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 686 K S e 53.8 8dvs_A 0 0 0 0 0 0 2 0 31 0 0 0 0 3 61 1 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 687 A S e 67.9 8dvs_A 18 1 4 5 3 5 1 3 7 9 4 3 3 3 10 6 6 4 1 4 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 688 S S e 87.5 8dvs_A 1 0 13 4 0 5 6 1 13 1 0 5 1 4 2 27 16 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 689 G S e 29.8 8dvs_A 1 0 0 0 0 89 0 0 4 1 0 0 0 0 0 1 0 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 690 D S e 58.6 8dvs_A 5 0 9 24 0 2 2 3 15 2 0 5 0 2 15 6 7 2 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 691 H b 19.9 8dvs_A 4 2 0 0 5 0 2 16 12 9 0 3 0 0 0 9 12 13 0 13 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 692 N S b 12.1 8dvs_A 0 0 2 0 0 0 2 0 2 0 0 75 9 0 3 5 2 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 693 I B b 0.0 8dvs_A 0 15 0 0 0 0 0 20 0 37 2 0 0 0 0 0 9 17 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 694 L b 0.0 8dvs_A 0 0 0 0 0 0 0 25 0 64 10 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 695 I b 0.0 8dvs_A 0 0 0 0 16 0 0 33 0 1 0 0 0 0 0 0 0 50 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 696 A B b 0.0 8dvs_A 74 7 0 0 0 2 0 0 0 0 0 0 0 0 0 5 12 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 697 T b 12.3 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 96 0 0 0 MUTAGEN:/note="TSVAD->ASVAA: No effect on dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="TSVAD->ASVAA: No effect on dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 698 S G e 54.7 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 2:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 MG 6 3 24 0 0 0 0 0 1 0 0 0 0 2 0 61 2 0 0 0 MUTAGEN:/note="TSVAD->ASVAA: No effect on dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="TSVAD->ASVAA: No effect on dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 699 V G b 16.7 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:dsRNA strand 2:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30 2 0 0 0 0 0 0 24 0 3 0 0 0 0 0 0 0 70 0 0 MUTAGEN:/note="TSVAD->ASVAA: No effect on dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="TSVAD->ASVAA: No effect on dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 700 A G b 0.0 8dvs_A RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*.. BU3 37 0 0 0 0 24 0 0 0 32 0 0 0 0 0 2 2 4 0 0 MUTAGEN:/note="TSVAD->ASVAA: No effect on dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="TSVAD->ASVAA: No effect on dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 701 D S b 4.3 8dvs_A BU3 8 0 4 80 0 0 0 0 2 0 0 0 0 0 0 7 0 0 0 0 MUTAGEN:/note="TSVAD->ASVAA: No effect on dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="TSVAD->ASVAA: No effect on dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 702 E S e 23.6 8dvs_A p1dsRNA:OHdsRNA:p3SLR30 DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa] BEF:ETF:BU3 0 0 0 86 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 703 G S e 20.2 8dvs_A ALF 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 704 I b 11.1 8dvs_A 0 0 0 0 0 0 0 40 0 53 0 0 0 0 0 0 0 7 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 705 D e 67.3 8dvs_A ADP BU3 0 0 98 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 706 I b 9.9 8dvs_A 0 0 0 0 0 0 0 62 0 1 0 0 0 0 0 0 0 37 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 707 A e 26.8 8dvs_A 5 0 0 0 0 20 0 0 4 0 1 0 43 11 7 8 1 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 708 Q e 35.7 8dvs_A 15 0 12 22 0 1 5 4 6 0 0 8 0 15 0 7 3 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 709 C b 0.0 8dvs_A 0 63 0 0 0 0 0 4 0 0 0 0 0 0 0 0 1 31 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 710 N S b 17.6 8dvs_A 4 3 21 1 0 0 1 0 0 0 0 48 0 0 1 13 7 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 711 L E b 0.6 8dvs_A 0 3 0 0 0 0 15 3 0 56 5 0 0 0 0 0 2 15 0 2 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 712 V E b 0.0 8dvs_A 0 0 0 0 0 0 0 26 0 0 0 0 0 0 0 0 0 74 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 713 I E b 0.6 8dvs_A 0 0 0 0 4 0 0 57 0 4 1 0 0 0 0 0 0 34 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 714 L E b 3.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa] BU3 0 36 0 0 2 0 0 4 2 4 0 16 0 0 36 0 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 715 Y E b 0.9 8dvs_A 0 0 0 0 52 0 0 0 0 4 0 0 0 0 0 0 0 0 2 42 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 716 E S b 14.6 8dvs_A 0 0 83 7 0 4 0 0 0 0 0 5 0 0 0 0 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 717 Y b 3.0 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa] BU3 7 2 0 2 0 1 0 5 8 40 1 0 11 0 2 10 3 0 0 8 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 718 V e 34.7 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 BU3 5 3 0 0 0 0 2 2 0 2 0 2 42 5 0 11 6 12 0 8 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 719 G e 39.3 8dvs_A RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:p2dsRNA:p3SLR30:OHSLR30 DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa] BU3 11 0 3 3 0 6 1 0 16 4 0 12 6 1 7 16 12 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 720 N e 44.2 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30 DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[514 aa] BU3 0 0 11 4 0 2 0 0 0 0 0 30 0 0 0 23 31 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 721 V H b 1.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa] 0 0 0 6 6 0 0 7 0 23 4 0 21 0 0 0 3 15 0 16 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 722 I H b 12.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa] 2 5 4 2 0 0 0 44 13 7 0 4 0 0 13 0 5 2 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 723 K H e 21.7 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:dsRNA strand 1:dsRNA strand1:p3dsRNAa:p2dsRNA:OHdsRNA:p3SLR30 MG DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa] BU3 6 0 4 0 0 1 10 0 10 0 4 0 0 13 17 36 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 724 M H b 4.8 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa] BU3:ETF 0 1 0 0 27 0 0 0 0 3 18 6 0 0 10 0 1 0 0 34 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 725 I H b 8.8 8dvs_A 0 0 0 0 0 0 0 53 0 8 0 0 0 0 0 0 0 39 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 726 Q H b 5.1 8dvs_A ALF 0 0 0 0 0 10 4 0 0 0 0 0 0 86 0 0 0 0 0 0 MUTAGEN:/note="QTRGR->ATRGA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="QTRGR->ATRGA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 727 T H b 2.6 8dvs_A BU3:ETF 4 2 0 0 0 0 0 0 0 0 0 0 0 0 54 35 4 0 0 0 MUTAGEN:/note="QTRGR->ATRGA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="QTRGR->ATRGA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 728 R H b 8.3 8dvs_A ETF 0 0 0 0 0 0 0 6 12 0 20 0 0 0 54 3 7 0 0 0 MUTAGEN:/note="QTRGR->ATRGA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="QTRGR->ATRGA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 729 G T b 13.1 8dvs_A 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 MUTAGEN:/note="QTRGR->ATRGA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="QTRGR->ATRGA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 730 R T b 7.1 8dvs_A ALF 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 MUTAGEN:/note="QTRGR->ATRGA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal":MUTAGEN:/note="QTRGR->ATRGA: Loss of dsRNA-induced ATPase activity. Changed RIG-I signaling pathway.":DOMAIN:/note="Helicase C-terminal" 731 G b 0.0 8dvs_A 68 0 0 0 3 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 732 R e 23.3 8dvs_A ADP ALF 0 0 0 0 0 10 0 0 0 0 0 0 0 0 86 0 4 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 733 A S b 12.5 8dvs_A 20 0 0 2 0 6 8 0 26 0 10 2 0 7 15 0 4 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 734 R S e 50.6 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 7 0 3 11 1 1 0 0 13 0 4 3 9 4 31 1 8 2 0 1 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 735 G S e 65.5 8dvs_A 13 0 12 9 0 22 1 3 4 0 0 16 2 12 0 5 0 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 736 S b 6.2 8dvs_A 6 0 0 0 0 27 0 0 0 0 0 0 0 2 0 56 4 3 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 737 K E e 20.8 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[178 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 7 0 6 5 0 0 4 0 31 0 0 9 0 4 10 4 11 0 0 6 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 738 C E b 0.7 8dvs_A ETF 2 7 0 0 15 0 3 21 0 6 0 0 0 0 0 6 4 12 0 24 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 739 F E b 6.2 8dvs_A RN135_HUMAN:E3 ubiquitin-protein ligase RNF135[178 aa] DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 12 0 0 0 11 5 2 13 0 8 0 4 0 0 0 3 4 29 0 8 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 740 L E b 0.6 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa] 2 0 0 0 10 0 2 13 0 49 11 0 0 0 0 0 0 10 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 741 L E b 0.0 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa] 8 0 0 0 15 0 0 6 0 40 17 0 0 0 0 2 5 6 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 742 T E b 0.0 8dvs_A CL 7 0 0 0 10 0 0 7 0 18 2 3 0 0 0 3 28 20 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 743 S S b 16.4 8dvs_A 19 0 8 19 0 3 2 0 4 0 0 1 2 2 3 22 13 2 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 744 N e 53.3 8dvs_A CL 0 0 16 9 0 5 0 0 4 0 0 12 0 2 16 17 10 0 0 8 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 745 A H e 52.7 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[64.. 29 0 7 10 0 34 0 0 0 0 0 8 0 0 3 8 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 746 G H e 22.6 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[64.. 4 0 15 3 0 15 0 4 11 1 0 16 1 6 8 12 4 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 747 V H b 8.0 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 7 0 4 11 3 6 0 8 6 14 10 3 1 3 4 1 1 19 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 748 I H b 17.0 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 11 0 5 1 1 1 0 19 9 18 3 1 1 12 1 4 3 10 0 1 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 749 E H e 60.8 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[646 aa]:Antiviral innate immune response receptor RIG-I[64.. 14 0 9 31 1 1 6 3 5 1 0 4 1 6 4 4 7 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 750 K H e 48.6 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:dsRNA strand 1:dsRNA strand1:p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[495 aa]:Probable ATP-dependent RNA helicase DDX58[514 aa] 5 0 3 13 0 1 8 1 24 1 3 3 1 8 20 4 1 1 3 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 751 E H b 2.0 8dvs_A BU3 7 0 20 45 0 1 0 0 3 1 0 0 0 0 0 9 0 1 3 6 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 752 Q H e 50.0 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Antiviral innate immune response receptor RIG-I[64.. 4 0 6 4 0 1 8 3 5 27 3 7 1 15 10 3 3 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 753 I H e 41.5 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[65..:Antiviral innate immune response receptor RIG-I[61..:Antiviral innate immune response receptor RIG-I[64.. 10 3 1 3 0 1 0 30 1 19 3 0 1 0 1 7 7 13 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 754 N H b 2.4 8dvs_A BU3 8 0 9 12 1 3 6 1 7 1 4 39 1 1 1 4 1 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 755 M H e 29.0 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 11 0 6 8 4 5 6 1 4 22 8 4 1 1 3 1 8 7 0 1 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 756 Y H e 58.7 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Antiviral innate immune response receptor RIG-I[65..:Antiviral innate immune response receptor RIG-I[61..:Antiviral innate immune response receptor RIG-I[64..:Antiviral innate immune response receptor RIG-I[63.. 11 0 3 5 8 3 3 3 0 18 4 0 0 0 12 1 0 0 0 27 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 757 K H b 15.1 8dvs_A 4 0 0 17 0 4 3 0 34 6 0 0 0 15 14 1 0 1 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 758 E H b 11.1 8dvs_A 0 0 4 65 0 5 0 0 8 5 0 4 0 0 3 0 0 0 4 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 759 K H e 53.8 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 5 0 8 4 0 0 0 3 30 4 0 0 0 10 18 7 8 3 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 760 M H b 1.9 8dvs_A 0 0 0 15 0 0 0 27 0 15 17 0 0 0 11 0 7 4 0 0 DOMAIN:/note="Helicase C-terminal":DOMAIN:/note="Helicase C-terminal" 761 M H b 3.4 8dvs_A 0 0 0 4 0 0 0 3 0 22 41 5 0 0 5 0 0 7 0 11 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 762 N H e 44.8 8dvs_A 4 0 0 12 0 0 0 0 0 0 0 39 0 5 26 5 0 0 0 6 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 763 D H e 54.3 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa] 0 0 7 44 0 4 0 0 10 0 0 9 0 20 0 6 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 764 S H b 0.0 8dvs_A 46 0 0 18 0 0 0 0 0 0 0 4 0 0 0 32 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 765 I H b 7.6 8dvs_A 1 0 0 16 0 1 0 29 0 1 6 0 0 11 0 8 6 20 0 0 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 766 L H e 58.4 8dvs_A 9 0 0 1 0 1 4 6 17 26 11 4 0 0 0 11 1 7 0 0 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 767 R H e 39.5 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Antiviral innate immune response receptor RIG-I[63.. 15 4 0 7 0 1 0 13 13 6 0 5 0 0 29 1 4 1 0 0 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 768 L H b 3.9 8dvs_A 7 0 1 1 1 1 0 1 1 40 17 1 1 1 6 1 1 17 0 1 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 769 Q T e 21.9 8dvs_A 1 0 1 7 0 8 0 1 1 1 0 0 1 59 5 7 1 1 0 6 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 770 T T e 66.2 8dvs_A 0 0 0 0 0 0 0 0 8 7 0 11 0 6 8 36 13 0 0 6 MOD_RES:/note="Phosphothreonine; by CK2":DOMAIN:/note="Helicase C-terminal":MOD_RES:/note="Phosphothreonine; by CK2":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 771 W S e 37.8 8dvs_A 1 0 7 7 22 1 0 6 0 7 17 10 0 0 0 0 0 0 13 8 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 772 D e 71.0 8dvs_A 0 22 41 7 0 0 0 0 24 0 0 0 0 5 0 0 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 773 E H e 28.1 8dvs_A 0 0 0 57 0 0 0 0 10 0 0 0 12 16 5 0 0 0 0 0 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 774 A H e 35.7 8dvs_A 27 0 5 17 0 0 0 5 7 5 4 5 8 0 0 5 13 0 0 0 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 775 V H e 47.3 8dvs_A 0 0 0 17 0 0 0 23 4 23 0 0 0 0 15 0 0 18 0 0 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 776 F H b 4.3 8dvs_A 0 0 0 15 18 0 0 0 0 0 16 0 23 0 0 6 0 0 0 23 DOMAIN:/note="Helicase C-terminal":DISORDER:predicted by DISOPRED:DOMAIN:/note="Helicase C-terminal" 777 R H e 46.2 8dvs_A 9 0 0 24 0 11 9 0 21 0 0 0 0 5 12 0 0 9 0 0 DISORDER:predicted by DISOPRED 778 E H e 53.8 8dvs_A 20 0 24 19 0 0 9 0 5 0 0 6 9 0 0 0 8 0 0 0 DISORDER:predicted by DISOPRED 779 K H e 30.2 8dvs_A 1 0 9 1 0 1 0 1 36 1 0 0 1 0 33 10 6 1 0 0 DISORDER:predicted by DISOPRED 780 I H b 4.1 8dvs_A 1 0 1 1 0 1 0 53 9 18 6 0 1 0 1 1 1 6 0 0 DISORDER:predicted by DISOPRED 781 L H e 38.8 8dvs_A 1 0 1 9 9 1 11 1 1 44 0 0 1 0 10 9 1 1 0 0 782 H H e 64.4 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[63.. 9 0 10 10 0 1 43 1 1 1 0 0 1 15 5 1 1 1 0 0 783 I H b 18.1 8dvs_A 0 0 0 0 6 21 0 35 0 28 0 0 9 0 0 0 0 0 0 0 DISORDER:predicted by DISOPRED 784 Q H b 1.5 8dvs_A 0 0 0 9 0 0 0 0 17 0 0 21 0 35 0 11 0 0 0 6 DISORDER:predicted by DISOPRED 785 T H e 47.4 8dvs_A 5 9 23 0 0 5 0 6 0 0 5 9 0 11 0 6 11 10 0 0 DISORDER:predicted by DISOPRED 786 H H e 59.7 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[63.. 10 0 6 9 0 0 26 0 0 0 0 16 0 9 6 9 8 0 0 0 DISORDER:predicted by DISOPRED 787 E H e 25.1 8dvs_A 7 0 15 38 0 0 0 0 0 1 0 0 0 5 11 19 0 0 0 0 DISORDER:predicted by DISOPRED 788 K H b 18.4 8dvs_A 17 0 0 0 0 1 0 6 33 6 0 0 0 12 10 1 0 11 0 0 MUTAGEN:/note="K->R: Decreased polyubiquitination. Loss of function in RIG-I signaling pathway. Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA- binding; when associated with R-849, R-851, R-888, R-907 and R-909.":MUTAGEN:/note="K->R: Decreased polyubiquitination. Loss of function in RIG-I signaling pathway. Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA- binding; when associated with R-849, R-851, R-888, R-907 and R-909.":DISORDER:predicted by DISOPRED 789 F H e 70.3 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[65..:Antiviral innate immune response receptor RIG-I[61.. 7 0 0 0 6 1 10 7 6 37 6 0 0 0 0 1 0 18 0 0 DISORDER:predicted by DISOPRED 790 I H e 40.4 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[65..:Antiviral innate immune response receptor RIG-I[63..:Antiviral innate immune response receptor RIG-I[61.. 1 0 12 7 0 1 0 25 7 20 18 0 0 7 0 1 0 1 0 0 DISORDER:predicted by DISOPRED 791 R H b 14.2 8dvs_A 1 0 0 13 0 1 7 0 16 1 0 0 0 0 56 1 1 1 0 0 DISORDER:predicted by DISOPRED 792 D H e 39.5 8dvs_A 8 0 21 21 8 1 0 0 8 8 0 0 13 0 0 1 1 8 0 0 DISORDER:predicted by DISOPRED 793 S H e 64.1 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[63.. 21 0 0 14 0 1 0 0 8 1 8 16 0 0 0 14 1 1 0 15 DISORDER:predicted by DISOPRED 794 Q e 68.4 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[63..:Antiviral innate immune response receptor RIG-I[61.. 1 0 0 13 0 1 0 0 8 1 0 0 0 43 15 1 1 1 13 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 795 E e 70.9 8dvs_A 8 0 0 33 0 15 7 0 1 1 0 0 0 0 15 8 8 1 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 796 K e 43.4 8dvs_A 8 0 0 13 0 0 0 7 41 0 0 0 0 8 0 23 0 0 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 797 P e 87.6 8dvs_A 7 0 0 0 0 0 8 0 0 0 0 0 69 8 8 0 0 0 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 798 K e 45.3 8dvs_A 0 0 0 7 8 0 0 0 26 0 0 8 0 7 31 0 0 0 0 13 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 799 P e 61.2 8dvs_A 0 0 0 8 0 0 0 8 0 0 23 0 41 7 0 0 13 0 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 800 V e 91.3 8dvs_A 8 0 0 0 0 0 0 16 13 13 0 0 0 0 0 0 0 43 0 7 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 801 P e 50.4 8dvs_A 1 0 0 0 0 1 0 0 8 1 0 8 57 8 0 13 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 802 D B e 45.1 8dvs_A 13 0 43 9 0 1 8 0 0 1 0 0 0 8 0 14 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 803 K e 74.1 8dvs_A 13 0 0 0 0 24 0 0 28 1 0 8 0 0 0 1 13 0 0 8 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 804 E S e 40.7 8dvs_A 13 0 0 29 0 0 0 23 28 0 0 0 7 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 805 N e 42.4 8dvs_A 13 0 0 0 0 0 15 0 0 0 0 44 0 0 0 7 20 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 806 K E b 8.5 8dvs_A 0 0 0 0 0 0 0 0 33 7 0 8 23 0 13 0 0 15 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 807 K E b 17.5 8dvs_A 0 0 0 29 0 0 0 0 28 13 0 0 0 15 0 0 15 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 808 L E b 0.0 8dvs_A 1 0 1 1 8 1 0 1 1 67 0 1 1 1 1 1 14 1 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 809 L E b 5.1 8dvs_A 1 0 1 1 1 1 17 1 1 66 0 1 1 1 1 1 1 1 0 1 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 810 C E b 0.0 8dvs_A ZN:HG 0 65 0 0 0 0 17 0 0 0 0 0 0 0 0 19 0 0 0 0 BINDING:/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105":DOMAIN:/note="RLR CTR":BINDING:/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105":DOMAIN:/note="RLR CTR" 811 R T b 9.9 8dvs_A DNA (41-MER) 0 0 0 0 0 9 0 19 28 0 0 0 0 0 27 17 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 812 K T b 14.6 8dvs_A DNA (41-MER) 17 0 0 0 0 0 0 0 45 0 0 39 0 0 0 0 0 0 0 0 CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)":DOMAIN:/note="RLR CTR":CROSSLNK:/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)":DOMAIN:/note="RLR CTR" 813 C T b 8.7 8dvs_A ZN:HG 0 65 0 0 0 0 0 17 0 0 0 0 0 0 19 0 0 0 0 0 BINDING:/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105":DOMAIN:/note="RLR CTR":BINDING:/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105":DOMAIN:/note="RLR CTR" 814 K b 8.5 8dvs_A 0 0 0 0 0 0 0 0 45 0 19 0 0 0 0 19 17 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 815 A b 11.6 8dvs_A ZN 17 0 0 0 0 0 0 0 0 0 9 9 0 19 0 0 0 46 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 816 L E e 42.1 8dvs_A 19 0 0 0 18 0 0 0 0 44 0 0 19 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 817 A E b 4.5 8dvs_A 52 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 48 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 818 C E b 4.0 8dvs_A 19 45 0 0 0 19 0 0 0 0 0 0 0 0 17 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 819 Y E e 38.3 8dvs_A 0 0 0 0 0 0 10 0 0 0 0 0 0 19 0 19 0 0 0 52 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 820 T S b 5.2 8dvs_A 17 0 0 0 0 39 0 0 0 0 0 0 0 0 0 0 45 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 821 A T e 47.3 8dvs_A 26 0 0 19 0 19 0 0 0 0 0 0 0 0 0 36 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 822 D T e 24.7 8dvs_A 0 0 55 0 0 0 0 0 0 0 0 9 0 0 0 35 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 823 V E b 1.3 8dvs_A 0 0 0 0 0 0 0 37 0 55 0 0 0 0 0 0 0 8 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 824 R E b 13.0 8dvs_A 0 0 0 0 0 0 19 0 0 0 0 0 0 17 64 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 825 V E b 7.3 8dvs_A 0 0 0 0 0 0 0 0 24 0 11 0 0 0 0 0 21 44 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 826 I S b 11.7 8dvs_A 0 0 0 0 0 0 0 33 0 0 0 0 0 0 0 21 0 46 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 827 E S e 36.7 8dvs_A DNA (41-MER):p3SLR30:OHSLR30:p3dsRNA24b MG 21 0 0 79 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 828 E S e 91.0 8dvs_A p3SLR30:OHSLR30:p3dsRNA24b 0 0 0 10 0 24 0 0 34 0 0 0 0 21 0 0 11 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 829 C S e 62.7 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:dsRNA strand 1:dsRNA strand1:DNA (41-MER):p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 MG 0 21 0 0 0 0 0 0 0 0 23 0 0 0 0 11 24 21 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 830 H e 28.8 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:dsRNA strand 1:dsRNA strand 2:dsRNA strand1:DNA (41-MER):p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 GTP MG 0 0 0 0 0 0 79 0 0 0 0 0 0 0 0 0 21 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 831 Y E b 5.2 8dvs_A 0 0 0 0 11 0 47 0 0 0 0 0 0 0 0 0 0 0 0 42 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 832 T E b 1.3 8dvs_A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32 68 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 833 V E b 3.3 8dvs_A 0 0 0 0 0 0 0 0 0 0 0 47 0 0 0 0 0 53 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 834 L e 29.2 8dvs_A 0 0 0 0 0 0 0 0 0 42 23 0 0 0 0 0 0 36 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 835 G S e 45.2 8dvs_A 0 0 0 0 0 32 0 0 0 0 0 45 0 0 0 0 23 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 836 D H e 72.2 8dvs_A 0 0 53 0 0 0 0 0 0 0 0 0 47 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 837 A H e 78.6 8dvs_A 53 0 0 23 0 0 0 0 0 0 0 24 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 838 F H b 2.4 8dvs_A 0 0 0 0 79 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 839 K H e 57.1 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 0 0 0 0 0 0 0 0 44 0 0 0 0 0 11 24 0 21 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 840 E T e 73.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa] 2 0 1 45 1 13 0 1 1 2 0 13 1 1 1 1 1 13 0 1 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 841 C T e 24.7 8dvs_A 0 31 0 0 0 0 0 0 0 23 0 0 0 0 22 0 0 0 0 24 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 842 F E b 10.0 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[648 aa] 0 0 0 21 32 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 843 V E e 40.0 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 12 65 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 844 S E e 53.1 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 0 11 0 0 0 0 0 21 0 0 0 0 0 0 0 33 12 23 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 845 R E e 43.9 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 0 0 0 0 0 0 0 0 22 21 0 0 0 0 45 12 0 0 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 846 P E e 94.6 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 0 0 0 23 0 0 0 0 0 11 0 0 54 12 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 847 H b 9.9 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':DNA (41-MER):p3dsRNAa:p2dsRNA:p3SLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 M7G:GTP 0 0 0 21 0 0 32 0 0 0 0 35 0 0 0 0 0 12 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 848 P S e 44.2 8dvs_A M7G 0 0 0 0 0 0 0 0 44 0 0 0 44 0 0 0 0 12 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 849 K S e 24.1 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:DNA (41-MER) 23 0 0 0 0 0 0 12 32 0 0 0 0 0 0 21 0 12 0 0 MUTAGEN:/note="K->R: Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA-binding; when associated with R-788, R-851, R-888, R-907 and R-909.":DOMAIN:/note="RLR CTR":MUTAGEN:/note="K->R: Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA-binding; when associated with R-788, R-851, R-888, R-907 and R-909.":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 850 P e 65.1 8dvs_A 0 0 0 0 0 0 0 0 0 0 0 24 53 23 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 851 K e 42.0 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:DNA (41-MER):p3dsRNAb:p2dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 M7G:GTP 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 MUTAGEN:/note="K->R: Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA-binding; when associated with R-788, R-849, R-888, R-907 and R-909.":DOMAIN:/note="RLR CTR":MUTAGEN:/note="K->R: Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA-binding; when associated with R-788, R-849, R-888, R-907 and R-909.":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 852 Q e 57.1 8dvs_A DNA (41-MER) 0 0 0 0 0 0 0 14 29 0 0 0 0 13 0 14 0 31 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 853 F S e 34.4 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:DNA (41-MER):p3dsRNAa:p3dsRNAb:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 GTP 0 14 0 0 72 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 854 S S e 52.3 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:DNA (41-MER):p3dsRNAb:p2dsRNA:p3SLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 MG 29 0 14 0 0 14 0 0 31 0 0 0 0 0 0 13 0 0 0 0 MOD_RES:/note="Phosphoserine; by CK2":DOMAIN:/note="RLR CTR":MOD_RES:/note="Phosphoserine; by CK2":DOMAIN:/note="RLR CTR" 855 S S e 33.6 8dvs_A p3dsRNA24a 0 0 60 0 0 0 0 0 0 0 0 27 0 0 0 13 0 0 0 0 MOD_RES:/note="Phosphoserine; by CK2":DOMAIN:/note="RLR CTR":MOD_RES:/note="Phosphoserine; by CK2":DOMAIN:/note="RLR CTR" 856 F b 0.5 8dvs_A DNA (41-MER):p3dsRNA24a 0 0 0 0 26 0 0 14 0 0 0 0 0 0 0 0 0 0 31 29 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 857 E e 38.2 8dvs_A 0 0 0 40 0 0 0 0 16 0 0 0 0 29 15 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 858 K b 4.2 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:dsRNA strand 1:dsRNA strand1:DNA (41-MER):p3dsRNAa:p2dsRNA:OHdsRNA:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR30 M7G:GTP 0 0 0 0 0 0 0 14 40 0 0 0 31 0 0 0 14 0 0 0 MOD_RES:/note="N6-acetyllysine":DOMAIN:/note="RLR CTR":MOD_RES:/note="N6-acetyllysine":DOMAIN:/note="RLR CTR" 859 R e 46.2 8dvs_A p3SLR30:OHSLR30:p3dsRNA24b DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa] 0 0 0 0 0 31 0 0 14 0 0 29 0 0 26 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 860 A E b 12.5 8dvs_A 40 0 0 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 861 K E b 7.1 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:p3dsRNAa:p2dsRNA:p1dsRNA:p3SLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 M7G:GTP 0 0 0 29 0 0 0 0 40 0 0 0 0 0 0 0 15 16 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 862 I E b 0.0 8dvs_A 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 863 F E b 13.4 8dvs_A 0 0 0 0 26 0 0 29 0 0 0 0 0 0 15 16 0 0 0 14 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 864 C E b 5.3 8dvs_A ZN:HG 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 BINDING:/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105":DOMAIN:/note="RLR CTR":BINDING:/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105":DOMAIN:/note="RLR CTR" 865 A e 37.5 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa] 43 1 2 3 2 3 1 2 3 4 1 2 2 2 2 19 3 3 1 1 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 866 R S e 58.5 8dvs_A ZN 5 1 3 4 2 4 1 3 17 5 1 3 3 3 29 4 4 4 1 2 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 867 Q S e 86.2 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 3 1 2 3 2 3 1 2 3 4 1 2 16 28 18 3 3 3 1 1 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 868 N S e 25.5 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[648 aa]:Probable ATP-dependent RNA helicase DDX58[669 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 0 0 14 0 0 0 0 0 29 0 0 58 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 869 C b 2.7 8dvs_A ZN:HG 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 BINDING:/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105":DOMAIN:/note="RLR CTR":BINDING:/ligand="Zn(2+)" /ligand_id="ChEBI:CHEBI:29105":DOMAIN:/note="RLR CTR" 870 S e 42.2 8dvs_A ZN 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 40 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 871 H b 15.7 8dvs_A ZN 0 0 0 31 0 0 40 0 0 0 0 0 0 29 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 872 D B e 23.5 8dvs_A RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:p1dsRNA:p3dsRNA24a:p3SLR30:p3SLR14 M7G:GTP ETF 29 0 40 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 873 W b 2.0 8dvs_A ZN 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 874 G E b 9.5 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:p3dsRNA24a GTP 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 875 I E b 7.0 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:dsRNA strand 1:DNA (41-MER):p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 M7G:GTP 0 0 0 0 15 0 0 40 0 16 0 0 0 0 0 0 29 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 876 H E b 13.6 8dvs_A 0 0 0 0 14 0 13 0 0 0 29 0 0 31 0 0 0 0 0 14 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 877 V E b 0.0 8dvs_A p3SLR30:OHSLR30 0 0 0 0 0 0 0 0 0 0 60 0 0 0 0 0 0 40 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 878 K E e 24.5 8dvs_A dsRNA strand 2:p3SLR30:OHSLR30:p3dsRNA24b DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa] 0 0 0 0 0 0 0 31 13 0 0 0 0 0 27 0 0 29 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 879 Y S b 17.4 8dvs_A dsRNA strand 2:p3SLR30:OHSLR30:p3dsRNA24b 0 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 0 0 0 71 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 880 K S e 64.2 8dvs_A dsRNA strand 2:p3SLR30:OHSLR30:p3dsRNA24b DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[641 aa]:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[638 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa] 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 881 T S e 70.1 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Antiviral innate immune response receptor RIG-I[65..:Antiviral innate immune response receptor RIG-I[64.. 14 0 0 0 0 29 0 0 0 0 0 0 0 0 0 31 26 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 882 F S e 31.1 8dvs_A DDX58_HUMAN:Antiviral innate immune response receptor RIG-I[65..:Antiviral innate immune response receptor RIG-I[64.. 0 0 0 0 40 0 0 0 0 29 0 0 0 0 0 0 0 31 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 883 E E e 35.2 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[668 aa]:Probable ATP-dependent RNA helicase DDX58[653 aa]:Probable ATP-dependent RNA helicase DDX58[647 aa] 0 0 29 40 0 0 0 0 16 0 0 0 0 0 0 0 15 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 884 I E b 11.1 8dvs_A 0 0 0 0 0 0 0 26 0 60 14 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 885 P E b 8.5 8dvs_A 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 886 V E b 10.7 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:DNA (41-MER):p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:OHSLR30:p3dsRNA24a GTP 0 29 0 0 14 0 0 0 0 0 0 0 0 0 0 0 0 58 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 887 I E b 5.3 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:p3SLR14 0 0 0 0 0 0 0 40 0 60 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 888 K e 28.3 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:dsRNA strand 1:dsRNA strand1:p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 M7G:GTP BU3:ETF 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 MUTAGEN:/note="K->R: Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA-binding; when associated with R-788, R-849, R-851, R-907 and R-909.":DOMAIN:/note="RLR CTR":MUTAGEN:/note="K->R: Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA-binding; when associated with R-788, R-849, R-851, R-907 and R-909.":DOMAIN:/note="RLR CTR" 889 I G b 0.6 8dvs_A 0 0 0 0 0 0 0 84 0 0 0 0 0 0 0 0 0 16 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 890 E G e 49.7 8dvs_A RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:DNA (41-MER):p3SLR30 MG 0 0 0 40 0 15 0 0 0 0 0 0 0 0 45 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 891 S G b 3.1 8dvs_A 0 0 0 0 0 0 0 0 0 0 0 29 0 0 0 71 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 892 F E b 0.0 8dvs_A 0 0 0 0 69 0 0 15 0 0 16 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 893 V E b 0.0 8dvs_A 0 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 0 69 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 894 V E b 2.0 8dvs_A 0 0 0 0 0 0 0 0 0 31 0 0 0 0 0 0 0 69 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 895 E E b 3.5 8dvs_A 0 0 0 71 0 0 0 0 0 0 0 14 0 0 0 0 0 14 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 896 D E b 11.1 8dvs_A 0 0 40 0 29 0 0 0 0 0 0 0 0 0 0 0 31 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 897 I S e 48.0 8dvs_A 0 0 0 0 0 0 0 40 29 0 0 0 31 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 898 A S e 67.0 8dvs_A 26 0 0 0 0 0 0 0 0 0 0 29 0 16 15 0 0 14 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 899 T S e 64.3 8dvs_A 0 0 0 0 0 31 0 0 0 0 0 29 0 0 0 14 26 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 900 G b 14.3 8dvs_A 0 0 0 0 0 40 0 0 15 0 0 0 0 0 16 29 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 901 V e 58.0 8dvs_A 0 0 0 0 0 0 0 31 0 0 0 0 14 0 0 0 14 40 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 902 Q E b 11.2 8dvs_A 0 0 0 0 0 0 0 0 29 0 0 0 0 71 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 903 T E e 31.8 8dvs_A 31 0 0 0 0 0 0 0 29 0 0 14 0 0 0 0 26 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 904 L E e 21.3 8dvs_A DNA (41-MER) 2 1 2 2 1 2 1 2 2 16 1 1 2 30 15 2 2 16 0 1 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 905 Y e 23.5 8dvs_A 2 1 2 2 1 2 28 2 2 3 1 1 2 1 2 2 2 2 0 42 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 906 S S e 58.6 8dvs_A RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:DNA (41-MER):p2dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3SLR14 14 0 0 0 0 0 0 0 60 0 0 0 0 0 0 26 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 907 K S e 55.7 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:dsRNA strand1:DNA (41-MER):p3dsRNAa:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24b:p3dsRNA24a:p3SLR14 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 MUTAGEN:/note="K->R: Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA-binding; when associated with R-788, R-849, R-851, R-888 and R-909.":DOMAIN:/note="RLR CTR":MUTAGEN:/note="K->R: Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA-binding; when associated with R-788, R-849, R-851, R-888 and R-909.":DOMAIN:/note="RLR CTR" 908 W G b 12.4 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(*CP*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*U)-3')..:RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*..:RNA (5'-R(*GP*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3')..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:dsRNA strand 1:dsRNA strand1:DNA (41-MER):p3dsRNAa:p2dsRNA:p1dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 909 K G e 67.5 8dvs_A 5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3':RNA (5'-R(P*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP..:RNA (5'-R(*GP*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*..:RNA (5'-R(P*AP*AP*UP*AP*UP*AP*AP*UP*AP*GP*UP*GP*AP..:RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)..:dsRNA strand 1:dsRNA strand1:p3dsRNAa:p2dsRNA:OHdsRNA:p3SLR30:OHSLR30:p3dsRNA24a:p3dsRNA24b:p3SLR14 0 0 0 0 0 0 0 0 55 0 0 0 0 0 0 45 0 0 0 0 MUTAGEN:/note="K->R: Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA-binding; when associated with R-788, R-849, R-851, R-888 and R-907.":DOMAIN:/note="RLR CTR":MUTAGEN:/note="K->R: Decreased ubiquitination and function in RIG-I signaling pathway without effect on RNA-binding; when associated with R-788, R-849, R-851, R-888 and R-907.":DOMAIN:/note="RLR CTR" 910 D G e 53.1 8dvs_A OHSLR30 0 0 55 0 0 0 0 0 0 0 0 0 0 0 45 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 911 F b 1.0 8dvs_A 0 0 0 0 55 0 0 0 0 0 0 0 0 0 0 0 0 45 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 912 H e 51.8 8dvs_A 0 0 0 0 0 0 36 0 0 0 0 18 45 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 913 F B b 2.4 8dvs_A 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 914 E e 46.2 8dvs_A 0 0 0 55 0 0 0 0 0 0 0 0 0 0 0 45 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 915 K e 34.0 8dvs_A 0 0 0 0 0 0 0 22 36 0 0 0 0 0 19 0 0 23 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 916 I E e 33.3 8dvs_A 0 0 0 0 0 0 0 36 0 18 0 0 45 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 917 P E e 74.4 8dvs_A 0 0 23 0 0 0 0 0 0 0 0 0 18 19 0 18 0 22 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 918 F b 19.1 8dvs_A 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 919 D e 53.7 8dvs_A 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 920 P S e 81.4 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Antiviral innate immune response receptor RIG-I[64.. 33 0 0 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 921 A e 51.8 8dvs_A DDX58_HUMAN:Probable ATP-dependent RNA helicase DDX58[644 aa]:Probable ATP-dependent RNA helicase DDX58[650 aa]:Probable ATP-dependent RNA helicase DDX58[672 aa]:Probable ATP-dependent RNA helicase DDX58[673 aa]:Probable ATP-dependent RNA helicase DDX58[637 aa]:Probable ATP-dependent RNA helicase DDX58[646 aa]:Antiviral innate immune response receptor RIG-I[64.. 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DOMAIN:/note="RLR CTR" 922 E e 83.4 8dvs_A 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 923 M e 51.7 5f9f_K 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 924 S e 64.1 2rmj_A 33 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR" 925 K e 117.5 2rmj_A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="RLR CTR":DISORDER:predicted by DISOPRED:DOMAIN:/note="RLR CTR"