site aa pred_sec pred_expbur pred_accessibility pdb_asym_id hetero nucleotide compound metal otherpoly homo precipitant A C D E F G H I K L M N P Q R S T V W Y feature_table variant 1 M 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 2 E 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 3 N 0 0 0 0 0 0 0 0 0 0 0 60 0 0 0 0 0 0 0 40 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 4 M 0 0 0 0 0 0 0 0 0 0 81 0 0 19 0 0 0 0 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 5 F 0 0 0 0 31 0 0 35 0 0 0 0 15 0 0 0 0 18 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 6 L 0 0 0 0 0 0 0 0 0 78 10 0 12 0 0 0 0 0 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 7 Q 13 0 0 0 0 0 0 0 14 0 0 0 0 39 34 0 0 0 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 8 S 11 0 0 0 0 0 0 0 0 7 12 0 19 0 13 39 0 0 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 9 S 0 0 0 0 0 12 0 8 0 11 0 0 14 0 13 32 0 0 11 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 10 M 0 0 0 0 0 0 0 27 0 29 8 0 0 9 0 6 12 0 9 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED M->V:LB/B:rs5744077: -; 11 L 1 5 0 1 10 8 0 16 1 45 0 0 0 0 0 1 1 9 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 12 T 6 0 0 1 0 1 10 0 1 12 0 0 0 0 0 36 23 8 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 13 C 0 67 0 0 0 0 0 0 0 10 6 0 10 0 0 0 0 0 8 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 14 I 7 0 0 0 30 0 0 9 0 29 0 0 4 0 0 0 0 14 8 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 15 F 0 6 0 0 33 4 0 11 0 17 0 0 0 0 0 8 0 4 9 8 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 16 L 9 0 0 0 0 0 0 13 0 67 0 0 0 0 0 0 4 7 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 17 L 7 6 0 0 0 6 0 0 0 69 0 0 0 0 0 0 0 12 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 18 I 0 0 0 0 20 0 0 17 0 26 0 0 0 0 0 6 7 21 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 19 S 6 0 0 0 0 8 0 0 0 15 4 0 7 7 0 51 0 0 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 20 G 30 0 0 0 0 46 0 0 0 4 0 0 0 0 0 10 0 7 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 21 S 11 0 0 0 4 16 0 6 0 0 0 0 0 0 7 48 5 0 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 22 C 14 41 0 1 0 13 0 0 1 6 0 0 0 0 0 5 15 1 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 23 E 10 5 0 36 0 1 0 3 6 1 0 0 0 17 7 6 6 1 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 24 L 11 0 0 0 4 15 0 9 0 28 11 0 4 0 0 1 5 10 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 25 C 5 50 5 0 4 5 0 5 0 10 0 0 0 0 0 0 10 0 5 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 26 A 28 3 0 0 0 6 3 0 0 3 0 0 15 4 4 9 15 8 0 0 SIGNAL::SIGNAL::DISORDER:predicted by DISOPRED 27 E 12 3 4 17 1 5 0 1 10 7 0 1 16 9 7 3 4 1 0 0 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 28 E 7 0 3 30 1 10 0 1 1 3 0 5 1 13 15 5 4 1 0 0 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 29 N 5 8 2 2 1 11 3 1 2 6 1 34 1 1 9 7 4 2 0 1 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 30 F e 113.4 6zjz_B 10 15 2 2 18 2 1 5 5 10 1 1 2 5 4 6 2 5 0 5 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 31 S e 110.9 4qbz_A 16 4 1 1 1 1 0 6 1 7 0 4 18 1 1 28 4 3 0 3 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 32 R b 12.3 4qbz_A 9 8 1 3 1 6 3 1 9 7 0 5 1 10 15 11 1 1 3 4 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 33 S e 27.3 4qbz_A 9 0 7 7 5 7 0 1 1 5 0 1 14 4 1 27 8 1 0 1 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 34 Y e 28.7 4qbz_A 1 8 1 1 7 1 9 1 5 17 0 1 1 11 4 6 3 8 3 13 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 35 P S b 9.3 4qbz_A 2 0 1 1 3 5 0 1 5 1 2 1 67 1 1 6 1 2 0 0 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 36 C S b 2.7 4qbz_A 6 77 0 0 0 0 0 0 3 0 0 0 0 0 0 8 3 2 0 0 DISULFID::TOPO_DOM:/note="Extracellular":DISULFID::DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 37 D E e 31.5 4qbz_A 2 0 20 13 2 0 2 7 0 0 1 0 24 2 1 11 8 6 0 0 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 38 E E b 19.1 4qbz_A 5 25 2 13 2 4 5 5 5 9 0 2 4 3 1 3 3 4 2 3 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 39 K E e 42.0 4qbz_A 2 0 7 3 0 6 2 1 17 1 0 1 4 10 15 11 13 7 0 0 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 40 K e 65.1 4qbz_A 4 19 4 12 0 2 4 4 7 6 0 6 10 4 7 2 3 4 0 2 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 41 Q e 51.5 4qbz_A 4 1 4 3 0 1 7 4 0 6 0 1 4 24 19 10 6 2 0 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 42 N S e 90.9 4qbz_A 4 17 4 5 2 10 6 1 6 1 0 13 4 4 4 10 6 2 2 0 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular" 43 D S e 102.5 4qbz_A 4 2 19 11 4 3 2 4 6 8 2 2 2 4 7 15 1 3 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 44 S b 15.6 4qbz_A 9 0 1 3 1 11 2 1 4 15 5 2 2 1 4 20 15 3 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 45 V b 12.7 4qbz_A 3 0 3 1 1 6 0 7 6 14 3 4 1 3 5 3 12 28 0 4 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 46 I E b 11.1 4qbz_A 6 0 1 2 5 2 1 13 4 21 1 1 1 1 2 6 10 21 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 47 A E b 0.0 4qbz_A 9 6 2 1 2 1 0 3 1 18 4 1 3 1 1 5 4 35 0 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 48 E E e 34.2 4qbz_A 2 0 37 7 2 0 2 5 3 8 0 6 0 5 2 9 1 1 0 8 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 49 C b 0.0 4qbz_A 4 79 0 0 0 3 0 3 2 4 0 0 0 0 0 3 2 1 0 0 DISULFID::TOPO_DOM:/note="Extracellular":DISULFID::TOPO_DOM:/note="Extracellular" 50 S e 24.2 4qbz_A 6 0 11 5 0 6 7 2 1 1 2 9 2 1 3 34 7 4 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 51 N S e 70.9 4qbz_A 0 1 13 4 0 22 7 0 6 2 0 19 0 1 8 10 0 2 3 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 52 R S b 12.6 4qbz_A 6 1 1 5 0 2 2 1 11 19 1 10 0 7 29 2 2 3 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 53 R e 48.6 4qbz_A 3 0 8 6 6 22 3 0 10 3 1 13 0 5 14 6 0 0 1 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 54 L b 12.9 4qbz_A 2 0 1 0 3 0 0 5 0 79 1 0 1 0 0 1 3 3 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 55 Q S e 62.8 4qbz_A 5 0 6 3 1 7 3 1 14 4 2 3 3 7 7 15 13 5 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 56 E S e 70.9 4qbz_A 11 0 3 26 3 1 1 0 8 0 1 1 2 7 9 14 9 3 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 57 V b 5.3 4qbz_A 3 1 0 0 5 0 0 32 0 14 4 0 0 0 0 0 1 39 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 58 P b 11.6 4qbz_A 3 0 0 0 0 0 0 0 0 0 0 0 92 0 0 3 0 2 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 59 Q S e 64.3 4qbz_A 4 0 6 11 0 5 3 1 7 2 2 2 10 11 8 17 5 4 1 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 60 T e 58.4 4qbz_A 4 4 10 6 3 18 0 2 2 2 0 12 5 1 3 13 10 5 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 61 V b 10.0 4qbz_A 2 0 0 0 4 0 0 29 0 38 0 0 3 0 2 4 2 13 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 62 G b 10.7 4qbz_A 3 0 4 3 2 18 0 1 0 1 2 0 46 2 1 9 3 1 3 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 63 K T e 69.8 4qbz_A NAG TLR8_HUMAN:Toll-like receptor 8[747 aa] 9 1 2 6 1 2 2 3 12 2 2 4 11 5 16 14 4 2 2 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 64 Y T e 48.7 4qbz_A NAG TLR8_HUMAN:Toll-like receptor 8[747 aa] 5 0 10 3 4 5 10 4 2 4 1 16 1 3 8 8 3 0 2 10 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 65 V b 1.3 4qbz_A 5 1 0 0 0 1 0 15 0 27 1 3 0 0 0 2 31 13 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 66 T b 18.8 4qbz_A 5 0 2 10 0 0 1 3 12 3 4 2 0 10 10 5 21 9 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 67 E E e 20.6 4qbz_A 3 1 7 15 3 1 5 2 3 7 3 5 0 6 6 11 3 7 2 11 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 68 L E b 1.1 4qbz_A 1 0 0 0 2 0 0 9 0 84 0 0 0 0 0 0 0 2 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 69 D E e 25.9 4qbz_A 1 0 43 7 2 1 5 3 1 1 0 7 0 3 4 7 3 2 1 7 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 70 L b 0.0 4qbz_A 0 0 0 3 6 0 0 10 0 74 2 0 0 0 0 2 0 3 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 71 S b 8.6 4qbz_A SO4 7 0 5 2 0 3 5 1 1 4 1 2 2 14 5 37 5 4 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 72 D S b 17.9 4qbz_A 6 2 12 6 4 8 10 1 2 0 4 20 0 2 6 9 2 0 1 6 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 73 N S b 0.0 4qbz_A 0 3 0 0 0 3 0 0 0 0 0 85 0 3 0 2 4 0 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 74 F e 29.2 4qbz_A 4 1 4 10 5 3 8 0 7 3 1 17 2 11 13 5 2 0 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 75 I b 0.0 4qbz_A 0 0 2 0 15 0 0 45 0 33 1 0 1 0 0 0 0 2 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 76 T e 37.0 4qbz_A 5 0 1 5 0 1 4 1 8 1 1 1 4 4 9 16 36 3 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 77 H E e 58.1 4qbz_A NAG 4 1 6 10 5 16 12 2 8 1 1 2 0 3 8 6 9 3 0 4 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 78 I E b 0.0 4qbz_A 0 0 3 3 0 2 0 33 1 39 0 0 3 1 1 4 2 8 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 79 T e 30.5 4qbz_A NAG 5 0 3 7 2 7 7 9 5 3 0 4 17 5 5 9 5 5 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 80 N T e 55.8 4qbz_A NAG 9 1 7 8 0 3 2 1 6 2 0 14 24 2 6 7 6 1 0 3 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular" 81 E T e 60.3 4qbz_A NAG 10 0 11 14 0 8 3 1 6 5 1 10 2 4 9 10 1 1 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 82 S T b 10.9 4qbz_A 17 0 15 3 1 3 1 1 1 7 1 4 4 1 3 23 9 2 1 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 83 F T b 2.4 4qbz_A 0 0 0 0 65 2 0 3 0 20 2 0 1 0 0 0 3 2 3 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 84 Q T e 67.3 4qbz_A NAG 9 0 2 4 1 15 3 2 7 4 0 3 3 16 7 11 7 2 3 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 85 G T e 67.9 4qbz_A NAG 4 0 4 6 1 26 4 0 3 0 0 26 2 3 8 9 2 1 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 86 L b 6.7 4qbz_A 5 4 0 0 5 0 0 4 1 54 6 2 0 4 0 4 1 5 0 5 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 87 Q T e 40.3 4qbz_A NAG TLR8_HUMAN:Toll-like receptor 8[747 aa] 2 1 2 4 1 2 4 0 6 4 2 3 18 5 9 14 19 4 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 88 N T e 49.7 4qbz_A NAG TLR8_HUMAN:Toll-like receptor 8[747 aa] 5 0 6 2 4 3 8 0 2 2 1 30 0 6 6 16 4 1 0 2 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular" 89 L b 0.0 4qbz_A 1 0 0 0 0 0 0 3 0 89 3 0 0 0 0 0 1 1 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 90 T e 26.0 4qbz_A 3 0 1 15 0 2 2 3 8 5 1 0 0 11 16 2 24 6 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 91 K E e 25.9 4qbz_A 5 0 6 14 2 1 4 6 13 4 1 4 0 3 5 11 6 9 5 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 92 I E b 0.0 4qbz_A 0 0 0 0 2 0 0 9 0 73 4 0 0 0 0 0 0 9 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 93 N E b 13.9 4qbz_A SO4 3 0 17 2 1 1 6 8 4 2 2 21 0 4 6 9 2 5 2 6 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 94 L b 0.0 4qbz_A 1 0 0 0 4 0 0 4 0 76 2 0 0 5 0 0 0 3 2 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 95 N b 7.3 4qbz_A SO4 6 0 8 2 2 6 5 2 4 3 1 12 2 5 3 30 2 3 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 96 H S b 8.4 4qbz_A SO4 4 1 7 6 6 7 17 2 4 4 1 15 1 4 9 3 1 1 2 5 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 97 N b 0.6 4qbz_A 1 3 1 3 3 1 0 1 1 2 0 71 1 1 1 5 3 1 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 98 P S e 24.0 4qbz_A 7 5 4 6 3 5 1 4 9 6 1 4 12 7 4 7 7 5 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 99 N e 39.4 4qbz_A 5 1 4 6 5 5 5 15 5 12 1 8 4 4 3 6 5 4 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 100 V e 110.7 4qbz_A TLR8_HUMAN:Toll-like receptor 8[751 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[708 aa] 6 5 3 4 5 5 1 8 4 15 3 2 4 3 4 9 8 8 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 101 Q e 93.9 4r09_B TLR8_HUMAN:Toll-like receptor 8[754 aa]:Toll-like receptor 8[749 aa] 5 1 3 8 5 9 1 3 7 6 1 2 8 11 8 9 6 4 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 102 H 8 1 2 6 4 6 17 3 4 10 1 4 6 3 5 7 4 6 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 103 Q 7 1 3 8 4 5 2 5 4 16 3 3 4 9 7 7 4 5 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 104 N 6 1 3 6 3 10 3 6 4 11 1 10 5 3 3 11 7 3 1 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 105 G 7 1 4 6 3 22 3 4 3 10 2 3 4 3 5 7 7 3 1 2 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 106 N 7 1 4 5 5 5 2 7 6 8 1 12 4 3 5 11 7 3 1 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 107 P 9 2 3 4 3 5 1 5 5 12 3 3 20 4 5 5 3 4 2 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 108 G 9 1 4 4 3 19 4 3 6 8 4 7 3 2 5 7 4 3 1 4 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 109 I 5 2 3 3 2 3 4 23 2 22 4 3 4 2 3 5 2 8 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 110 Q 8 2 4 9 5 5 2 3 7 6 1 3 5 10 8 13 4 3 0 1 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 111 S 5 2 3 4 2 7 2 5 2 8 1 5 6 4 3 27 7 4 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 112 N e 103.6 4r09_B 4 3 3 6 1 5 1 4 4 4 2 29 3 4 6 10 5 5 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 113 G e 70.2 4qbz_A 10 1 5 4 3 12 4 10 6 8 2 3 2 3 9 9 3 3 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 114 L b 3.9 4qbz_A 5 1 3 4 4 4 1 10 3 28 5 2 3 3 3 8 6 5 1 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 115 N E e 51.5 4qbz_A NAG 6 1 5 5 2 4 2 2 9 4 2 18 3 3 7 11 11 2 0 2 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular" 116 I E b 12.3 4qbz_A 4 1 1 2 1 5 1 37 2 19 1 1 1 1 1 8 1 13 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 117 T e 34.4 4qbz_A NAG 6 0 7 15 1 4 4 6 5 7 1 2 7 3 2 14 12 3 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 118 D T e 81.5 4qbz_A 7 0 17 9 2 4 3 4 5 3 0 3 22 2 3 5 2 7 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 119 G T b 15.5 4qbz_A 4 0 9 6 3 35 2 1 7 5 0 4 6 3 4 6 1 1 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 120 A T b 6.2 4qbz_A 39 1 4 4 1 6 2 7 1 4 1 0 2 4 3 8 5 7 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 121 F T b 1.4 4qbz_A 1 0 0 1 59 1 2 2 2 18 1 0 3 1 1 2 1 2 2 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 122 L T e 38.8 4qbz_A 6 0 4 4 2 5 3 1 6 23 0 5 2 7 9 12 3 7 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 123 N T e 60.6 4qbz_A NAG 3 1 13 5 1 23 3 1 6 3 0 17 4 3 2 11 2 1 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 124 L b 3.4 4qbz_A 3 2 0 0 4 0 0 4 0 66 5 1 1 2 0 5 1 3 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 125 K T e 66.5 4qbz_A 8 0 1 5 1 8 2 4 13 3 1 3 8 3 8 17 7 5 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 126 N T e 46.1 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] 3 0 3 4 1 6 8 0 12 1 1 24 1 7 7 15 5 0 0 2 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 127 L b 0.0 4qbz_A 0 1 0 0 2 2 0 3 0 80 2 2 0 0 0 0 2 4 0 0 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 128 R e 46.2 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] 2 1 3 13 0 1 1 1 16 4 3 3 0 9 27 2 7 3 0 1 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 129 E E e 24.1 4qbz_A 3 0 2 16 3 3 6 4 6 4 1 4 0 3 7 10 8 9 4 6 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 130 L E b 0.0 4qbz_A 3 0 0 1 5 1 0 5 0 71 1 3 0 0 0 1 0 7 0 0 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 131 L E b 11.2 4qbz_A SO4 1 1 13 6 3 2 9 8 2 8 4 10 0 1 6 5 7 5 1 10 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 132 L b 0.0 4qbz_A 2 7 0 0 3 0 0 8 0 65 3 0 0 0 0 2 0 7 0 0 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 133 E b 5.5 4qbz_A SO4 7 0 9 7 2 4 3 0 2 4 2 12 2 6 4 26 4 3 1 2 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 134 D S e 22.8 4qbz_A 1 0 16 7 3 12 9 0 5 1 0 14 2 3 5 12 1 0 0 8 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 135 N S b 1.2 4qbz_A 2 0 1 2 0 0 0 2 0 4 0 80 1 1 2 2 2 0 0 0 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 136 Q e 60.2 4qbz_A 4 1 3 5 3 1 7 3 10 5 1 12 2 20 11 8 0 1 1 1 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 137 L b 2.8 4qbz_A 1 3 0 0 5 0 0 18 0 52 5 0 0 0 0 3 5 5 0 0 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 138 P S e 67.4 4qbz_A 4 0 3 6 3 7 5 2 8 4 2 3 6 5 6 13 18 3 0 2 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 139 Q S e 53.1 4qbz_A NAG 6 0 4 19 3 10 3 0 5 5 3 4 3 4 4 9 5 8 0 3 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 140 I b 4.7 4qbz_A 8 0 8 8 8 1 0 8 0 8 8 8 8 0 0 8 8 8 0 0 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 141 P b 10.1 4qbz_A 5 2 2 3 3 2 0 5 1 3 2 3 54 1 2 7 2 3 0 0 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 142 S S e 26.6 4qbz_A 10 1 5 9 1 7 1 2 4 3 0 5 8 4 4 21 6 5 1 2 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 143 G S e 26.2 4qbz_A 8 1 4 5 2 37 1 1 2 6 0 5 6 3 2 10 2 2 0 1 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 144 L b 1.1 4qbz_A 5 2 1 1 6 0 3 6 1 50 2 0 2 1 2 4 3 4 3 1 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 145 P b 1.6 4qbz_A 4 2 1 2 11 4 2 1 2 18 1 1 35 0 2 5 6 2 0 1 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 146 E T e 50.3 4qbz_A 6 0 5 14 0 2 3 0 12 6 1 5 5 6 9 14 4 3 2 2 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 147 S T b 13.3 4qbz_A 8 0 9 3 0 5 3 2 5 2 2 10 6 2 4 27 8 1 0 3 REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 1":TOPO_DOM:/note="Extracellular" 148 L b 0.0 4qbz_A 5 0 0 0 5 0 2 6 0 59 4 0 0 0 4 0 4 7 0 0 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 149 T e 20.8 4qbz_A 3 0 2 15 2 5 1 3 5 13 2 4 2 10 3 4 16 4 3 3 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 150 E E b 18.1 4qbz_A SO4 4 0 5 16 3 0 6 2 5 7 4 8 0 8 6 11 7 4 1 2 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 151 L E b 0.0 4qbz_A 3 0 0 0 6 1 0 6 0 66 4 0 0 0 0 1 4 3 0 4 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 152 S E b 0.0 4qbz_A SO4 2 0 15 2 2 3 3 2 5 7 3 7 5 3 7 23 4 2 1 3 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 153 L b 0.0 4qbz_A 6 3 4 1 4 3 0 6 2 48 3 2 0 0 1 5 2 6 0 3 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 154 I b 1.8 4qbz_A 7 1 5 5 1 6 3 4 1 24 1 2 1 4 3 19 2 5 3 3 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 155 Q S b 7.7 4qbz_A 6 2 6 12 1 9 11 0 3 2 1 12 0 8 5 12 1 1 0 5 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 156 N S b 0.0 4qbz_A 0 0 2 0 0 6 2 0 0 2 0 74 1 1 1 4 4 1 0 1 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 157 N e 28.5 4qbz_A 5 2 5 6 2 1 4 1 13 5 1 22 2 8 9 7 2 2 0 2 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 158 I b 1.2 4qbz_A 2 1 0 1 8 0 1 39 1 29 2 1 3 0 0 3 2 5 0 0 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 159 Y b 15.7 4qbz_A 2 1 2 7 8 1 1 3 5 9 1 1 0 8 6 19 12 6 1 5 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 160 N E e 35.2 4qbz_A NAG 7 0 5 6 1 18 2 2 12 2 1 6 4 3 6 12 5 5 0 2 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 161 I E b 1.8 4qbz_A 2 0 1 3 1 1 1 21 2 31 1 1 1 3 2 7 4 16 0 1 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 162 T b 14.3 4qbz_A NAG 2 2 8 3 2 3 1 14 3 9 1 4 20 4 4 8 5 3 1 2 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 163 K H e 43.4 4qbz_A 7 0 8 7 3 8 0 0 11 4 1 3 21 4 5 7 3 1 3 1 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 164 E H e 62.3 4qbz_A NAG 9 0 7 23 3 7 3 1 6 4 1 6 3 4 4 12 2 1 1 2 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 165 G H b 2.4 4qbz_A 15 1 8 9 1 15 3 2 1 4 3 2 3 2 1 16 9 5 0 1 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 166 I H b 0.0 4qbz_A 2 1 0 4 33 0 2 17 0 21 2 0 4 0 2 1 2 5 2 0 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 167 S T b 14.1 4qbz_A 10 1 4 6 4 12 1 2 6 2 0 4 5 7 4 23 5 2 1 1 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 168 R T e 37.2 4qbz_A 5 0 4 8 3 21 6 0 6 1 3 7 3 6 17 6 2 2 0 2 REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 2":TOPO_DOM:/note="Extracellular" 169 L b 0.0 4qbz_A 4 6 0 0 3 1 0 2 2 53 6 0 1 5 0 3 4 5 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 170 I T e 35.7 4qbz_A 6 0 1 4 2 5 3 13 6 8 2 5 9 2 2 8 9 12 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 171 N T e 37.6 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] 5 2 12 2 1 3 3 0 8 1 0 30 2 10 5 12 1 1 0 1 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 172 L b 0.0 4qbz_A 3 0 0 0 4 0 0 7 0 72 3 0 3 0 0 0 0 4 0 0 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 173 K S e 42.0 4qbz_A 2 0 1 9 1 1 6 4 17 3 1 4 1 7 18 10 10 3 1 1 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 174 N E b 17.6 4qbz_A 3 1 2 6 3 0 6 3 4 4 3 14 4 2 7 12 9 10 1 4 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 175 L E b 0.0 4qbz_A 1 0 1 2 2 1 0 5 1 67 3 2 2 3 1 3 1 6 0 0 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 176 Y E e 21.3 4qbz_A SO4 3 2 14 7 7 2 5 4 3 6 1 8 1 5 6 5 3 7 3 10 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 177 L b 1.7 4qbz_A 1 0 0 1 2 1 0 6 1 60 6 2 2 0 0 7 2 8 0 0 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 178 A b 3.6 4qbz_A SO4 11 1 12 3 1 20 1 2 1 3 1 5 2 7 2 19 6 1 1 1 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 179 W S b 4.8 4qbz_A 2 3 7 3 3 12 9 6 4 4 1 7 2 5 5 6 4 2 9 6 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 180 N S b 1.2 4qbz_A 2 0 4 1 1 3 3 1 1 3 0 65 4 2 1 6 1 1 0 1 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 181 C S b 10.0 4qbz_A 9 9 2 3 3 5 5 2 3 16 4 7 6 4 3 9 3 4 0 3 DISULFID::REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":DISULFID::REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 182 Y e 22.6 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 2 1 1 4 9 4 4 7 3 25 1 6 2 2 4 8 2 4 0 11 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 183 F T e 29.2 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 4 1 3 4 14 4 5 6 4 13 2 6 3 3 2 9 5 5 1 5 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 184 N T e 79.4 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 4 1 9 3 3 13 1 2 5 4 2 18 3 2 5 8 8 4 1 1 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 185 K e 26.9 4qbz_A TLR8_HUMAN:Toll-like receptor 8[752 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 4 2 4 10 3 10 3 3 10 6 1 6 6 7 7 8 5 4 1 2 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 186 V S e 92.7 4qbz_A 5 1 2 6 3 4 1 18 2 18 2 2 8 3 3 4 3 10 1 2 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 187 C b 20.0 4qbz_A 7 17 4 4 3 5 3 4 5 12 1 3 10 3 2 8 3 4 1 1 DISULFID::REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":DISULFID::REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 188 E e 63.8 4qbz_A 4 1 11 19 1 8 2 2 4 6 1 4 6 8 6 6 6 4 0 2 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 189 K e 67.5 4qbz_A 4 1 2 6 1 4 3 9 10 15 2 5 4 5 7 12 3 5 0 1 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 190 T b 11.7 4qbz_A 7 0 6 6 1 6 1 5 6 5 2 4 3 3 5 14 15 10 0 1 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 191 N E e 55.2 4qbz_A NAG 4 3 7 8 1 17 3 1 4 6 1 8 5 3 4 14 4 3 1 4 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 192 I E b 19.3 4qbz_A 4 2 2 1 3 3 0 31 1 27 3 1 1 1 2 6 1 11 1 0 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 193 E e 32.7 4qbz_A NAG 7 3 6 21 2 4 3 1 5 4 1 2 12 4 3 11 2 4 3 0 REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 3":TOPO_DOM:/note="Extracellular" 194 D T e 51.9 4qbz_A 4 0 16 11 2 6 3 4 3 4 0 10 15 3 3 7 2 5 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 195 G T b 8.3 4qbz_A 5 2 4 4 1 40 4 1 5 4 0 7 4 2 5 6 2 2 1 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 196 V T b 0.7 4qbz_A 24 3 3 2 2 4 0 6 3 11 1 2 5 2 2 8 9 10 3 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 197 F T b 1.0 4qbz_A 1 1 1 3 46 1 0 6 1 23 1 0 3 0 1 2 2 3 1 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 198 E T e 51.3 4qbz_A 3 0 9 14 2 8 2 1 8 4 1 4 3 12 8 14 3 1 3 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 199 T T e 39.0 4qbz_A 4 2 4 3 1 17 4 2 5 3 0 11 3 2 4 14 11 5 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 200 L b 0.0 4qbz_A 1 2 0 0 2 0 0 2 0 62 9 0 1 4 0 3 2 8 2 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 201 T T e 56.5 4qbz_A NAG 3 1 0 8 1 6 3 2 10 3 0 4 10 4 5 17 17 6 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 202 N T e 45.5 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] 5 1 4 3 3 4 5 1 9 1 0 38 0 3 7 10 3 3 0 0 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 203 L b 0.0 4qbz_A 0 2 0 0 2 0 0 4 0 74 1 4 0 0 0 3 1 3 0 1 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 204 E e 36.2 4qbz_A 4 0 5 19 1 1 7 3 7 3 3 3 0 12 7 12 10 3 1 0 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 205 L E b 11.8 4qbz_A 4 1 3 10 9 1 3 5 4 13 4 1 0 5 3 5 5 10 1 14 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 206 L E b 0.0 4qbz_A 3 0 0 0 4 1 3 7 0 60 4 0 0 4 0 2 6 5 0 0 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 207 S E b 9.4 4qbz_A SO4 4 2 20 4 1 5 2 2 4 2 2 10 0 2 7 19 6 2 1 3 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 208 L b 1.1 4qbz_A 2 10 0 0 3 3 0 10 0 50 5 0 0 0 2 0 4 8 0 0 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 209 S b 6.2 4qbz_A SO4 11 2 5 7 0 5 5 4 8 3 0 3 4 4 3 26 3 3 0 2 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 210 F S b 3.8 4qbz_A 5 2 6 5 9 4 5 0 5 7 3 6 5 4 7 14 2 4 2 4 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 211 N S b 3.6 4qbz_A 4 5 3 3 2 3 0 0 2 4 2 48 0 6 4 4 4 0 2 2 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 212 S b 6.2 4qbz_A 2 2 5 6 3 5 2 1 12 4 2 18 2 6 15 11 2 1 0 2 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 213 L b 10.7 4qbz_A 0 0 0 0 9 3 0 20 0 54 2 0 0 0 0 3 4 3 0 0 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 214 S S e 32.8 4qbz_A 5 3 4 4 1 5 2 3 5 2 0 7 2 5 6 21 20 2 1 1 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 215 H S e 68.1 4qbz_A 7 0 3 5 3 14 10 2 8 1 1 7 3 3 6 10 9 3 2 3 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 216 V b 2.7 4qbz_A 4 0 3 3 6 2 0 21 3 16 4 4 3 2 2 5 3 14 0 4 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 217 P b 5.4 4qbz_A 6 0 2 5 4 3 4 10 0 10 3 2 33 2 2 3 3 4 0 3 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 218 P S e 62.0 4qbz_A 6 0 5 7 3 6 3 2 3 4 2 8 29 4 2 5 4 6 2 0 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 219 K e 44.8 4qbz_A 3 0 9 8 3 14 1 1 16 4 1 8 4 4 10 8 2 3 0 1 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 220 L b 13.5 4qbz_A 7 2 1 3 6 1 2 13 0 34 2 2 1 1 1 7 5 8 0 1 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 221 P b 7.8 4qbz_A 4 2 1 4 9 6 2 3 2 16 0 2 33 2 1 4 4 1 0 1 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 222 S T e 54.7 4qbz_A NAG 12 1 3 3 2 9 2 4 6 3 1 3 7 2 4 24 7 4 2 1 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 223 S T b 12.5 4qbz_A NAG 9 1 2 4 2 7 5 1 5 5 0 9 4 4 4 27 7 0 1 1 REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 4":TOPO_DOM:/note="Extracellular" 224 L b 0.0 4qbz_A 3 2 0 0 2 0 0 6 2 59 2 0 0 0 0 6 9 6 2 0 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 225 R S e 32.4 4qbz_A NAG TLR8_HUMAN:Toll-like receptor 8[747 aa] 3 0 2 6 0 4 5 2 19 3 5 4 2 10 18 4 6 4 0 1 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 226 K E e 36.8 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. 3 1 2 9 1 7 4 4 11 10 2 5 0 5 7 13 8 5 1 2 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 227 L E b 0.0 4qbz_A 1 2 0 2 2 1 2 4 4 69 0 2 0 0 2 3 0 5 0 0 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 228 F E e 23.9 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. SO4 1 1 10 4 9 2 8 7 3 8 1 8 1 2 4 6 4 5 1 13 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 229 L b 0.0 4qbz_A 4 0 0 0 3 2 0 3 0 61 3 2 0 2 2 0 4 6 0 6 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 230 S T b 3.1 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. 7 1 6 7 2 6 6 0 3 9 2 4 1 7 3 24 4 5 3 2 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 231 N T b 15.8 4qbz_A 2 0 7 8 3 6 7 0 3 2 0 34 0 2 8 10 2 0 1 4 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 232 T S b 0.0 4qbz_A 3 2 0 2 2 2 0 3 0 14 2 55 0 0 2 4 4 5 0 0 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 233 Q e 53.1 4qbz_A 3 1 7 4 1 3 6 1 9 4 4 8 5 14 12 6 4 3 0 3 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 234 I b 0.0 4qbz_A 3 0 2 3 5 4 2 37 5 24 1 3 0 0 0 3 0 5 0 2 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 235 K e 63.7 4qbz_A 4 1 4 8 1 7 2 2 7 3 1 14 3 5 10 13 10 2 0 1 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 236 Y E e 39.6 4qbz_A 5 0 3 6 5 13 5 3 4 4 2 5 0 3 3 12 7 4 2 12 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 237 I E b 0.0 4qbz_A 0 3 1 2 7 2 0 25 2 30 3 2 1 1 1 1 3 12 1 1 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 238 S b 17.2 4qbz_A 6 2 4 5 1 11 3 8 2 2 2 2 16 5 6 16 4 4 1 1 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 239 E T e 38.7 4qbz_A 7 2 10 11 1 6 1 3 6 3 2 3 23 5 4 7 3 2 0 1 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 240 E T e 57.8 4qbz_A 7 0 6 17 2 7 4 2 7 2 2 10 3 4 6 11 4 1 1 4 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 241 D T e 22.8 4qbz_A 11 3 18 10 1 6 0 3 4 4 2 7 2 1 2 13 8 1 1 4 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 242 F T b 1.0 4qbz_A 2 0 0 2 43 0 3 8 0 24 2 0 1 2 0 3 3 3 1 2 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 243 K T e 45.3 4qbz_A NAG 8 1 4 7 3 10 2 2 14 5 1 4 2 8 6 17 2 3 1 0 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 244 G T e 51.2 4qbz_A NAG 6 2 3 3 2 34 3 1 4 2 0 14 2 1 8 11 4 1 0 1 REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 5":TOPO_DOM:/note="Extracellular" 245 L b 3.4 4qbz_A 5 4 1 1 7 1 1 4 1 49 5 1 1 2 1 4 3 4 2 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 246 I T e 53.8 4qbz_A NAG 4 1 3 5 2 3 4 11 6 2 2 5 12 3 5 11 8 10 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 247 N T e 34.5 4qbz_A NAG 9 4 7 4 0 4 4 0 9 3 0 17 11 5 5 10 3 3 0 2 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 248 L b 0.0 4qbz_A 6 4 0 4 4 0 0 5 0 55 3 0 4 0 0 0 5 6 0 4 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 249 T e 22.1 4qbz_A 4 4 2 8 2 2 2 2 6 4 4 7 3 9 9 12 13 3 0 3 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 250 L E b 14.6 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. 8 3 3 6 4 4 5 9 6 11 3 2 2 2 6 6 7 8 1 4 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 251 L E b 0.0 4qbz_A 2 2 0 0 3 3 1 8 0 61 3 4 2 2 0 3 0 4 0 0 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 252 D E b 9.9 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. 1 0 29 6 2 4 4 3 5 5 0 8 0 1 8 7 7 4 3 2 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 253 L b 0.0 4qbz_A 3 3 1 1 5 2 0 5 1 61 8 0 1 0 0 2 1 4 0 2 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 254 S T b 0.8 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. 4 1 5 4 1 6 4 2 2 3 1 8 1 8 5 37 4 2 1 3 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 255 G T b 4.8 4qbz_A 4 0 4 2 4 27 8 1 2 5 0 9 2 4 5 10 2 3 1 6 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 256 N S b 0.0 4qbz_A 2 0 2 4 1 4 5 3 2 3 0 59 1 1 1 7 2 2 0 0 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 257 C S b 2.0 4qbz_A 6 16 4 3 2 6 2 9 4 10 3 5 4 6 3 8 3 5 0 1 DISULFID::REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":DISULFID::REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 258 P b 10.1 4qbz_A 5 1 2 6 1 3 1 14 3 9 1 4 26 2 5 4 3 5 2 3 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 259 R b 5.9 4qbz_A 6 0 5 4 0 4 4 4 7 5 4 9 3 4 16 9 7 4 0 4 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 260 C b 18.7 4qbz_A TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[736 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[749 aa] 8 9 7 5 3 7 3 8 4 10 4 3 1 5 4 9 4 4 0 3 DISULFID::REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":DISULFID::REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 261 F T e 48.3 4qbz_A CU8:7VF:7VC:7VL:DY3:O0W:QSM:GD0:I5N:RQY:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[736 aa] SO4 1 4 4 4 24 2 2 8 1 16 2 1 2 4 3 8 4 4 2 5 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 262 N T e 80.6 4qbz_A CU8:DY3 TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[733 aa]:Toll-like receptor 8[736 aa] 3 0 11 5 3 5 6 3 6 3 2 21 5 3 4 11 5 2 2 0 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 263 A e 30.4 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa] 14 7 4 8 0 10 4 5 4 10 2 4 3 4 3 6 6 3 1 2 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 264 P S e 73.6 4qbz_A UPT TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa] 5 0 4 4 1 4 4 6 4 11 0 2 22 4 6 12 4 4 0 2 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 265 F S b 14.8 4qbz_A UPT TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa] 7 3 7 7 9 3 3 9 4 14 0 6 3 0 4 6 3 4 4 4 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 266 P e 40.3 4qbz_A TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[736 aa] 6 0 6 6 0 6 6 6 6 6 6 6 6 6 6 6 6 6 6 0 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 267 C e 22.0 4qbz_A TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[736 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[749 aa] 3 14 2 4 4 4 2 11 3 10 6 4 0 2 6 9 5 3 3 3 DISULFID::REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":DISULFID::REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 268 V e 70.0 4qbz_A TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[736 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[749 aa] 6 0 0 6 6 6 6 6 6 6 6 0 6 6 6 6 6 6 0 6 REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 6":TOPO_DOM:/note="Extracellular" 269 P e 51.9 4qbz_A TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[749 aa] 4 0 4 7 5 5 5 6 6 10 0 7 13 3 3 8 3 4 3 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 270 C b 18.0 4qbz_A 9 15 3 4 4 6 2 3 4 17 2 3 4 2 3 8 3 6 2 1 DISULFID::TOPO_DOM:/note="Extracellular":DISULFID::TOPO_DOM:/note="Extracellular" 271 D G e 96.3 4qbz_A 4 1 15 11 2 4 1 5 4 10 1 9 5 3 7 9 5 3 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 272 G G e 103.6 4qbz_A 5 1 3 7 2 24 3 3 8 9 1 7 3 2 4 6 4 5 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 273 G G e 23.8 4qbz_A 6 2 3 3 3 20 2 7 8 9 2 8 3 2 3 9 6 3 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 274 A e 41.1 4qbz_A 10 1 2 7 4 9 3 5 4 12 1 6 4 3 4 9 7 5 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 275 S e 31.2 4qbz_A 5 1 4 5 1 4 1 10 4 14 1 4 3 4 3 24 5 4 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 276 I b 2.9 4qbz_A 5 2 2 4 2 7 2 11 5 23 4 3 2 2 1 5 9 8 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 277 N E e 58.2 4qbz_A 4 1 6 8 2 7 5 2 4 3 0 22 4 6 5 9 8 1 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 278 I E b 6.4 4qbz_A 3 1 2 5 2 2 2 28 2 20 4 2 3 2 2 3 4 13 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 279 D e 26.5 4qbz_A 5 0 15 19 1 6 2 3 3 4 1 4 13 3 3 9 5 2 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 280 R T e 35.2 4qbz_A 9 2 7 9 1 5 1 3 8 6 2 8 8 4 11 6 4 3 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 281 F T e 39.7 4qbz_A SO4 4 2 5 4 16 9 1 6 5 16 3 8 2 3 3 4 2 6 1 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 282 A T b 1.8 4qbz_A 24 2 3 4 1 9 0 3 4 8 2 3 3 2 1 16 8 4 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 283 F T b 1.0 4qbz_A 1 1 1 3 42 2 2 8 1 18 1 0 4 1 3 5 1 2 2 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 284 Q T e 28.1 4qbz_A NAG SO4 5 2 6 6 3 10 3 2 3 5 2 5 4 20 6 11 3 2 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 285 N T e 34.5 4qbz_A NAG 3 0 5 5 1 18 6 2 5 2 1 24 3 4 2 12 5 1 0 1 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular" 286 L b 0.0 4qbz_A 2 5 0 1 5 1 0 9 1 55 4 2 2 4 1 2 2 3 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 287 T T e 37.7 4qbz_A NAG 5 0 3 5 1 6 3 3 8 2 0 4 11 2 5 17 19 4 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 288 Q T e 33.2 4qbz_A NAG 4 1 1 10 2 4 6 0 7 4 1 16 2 11 8 17 2 1 0 2 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 289 L b 0.0 4qbz_A 1 1 0 2 0 0 0 8 0 76 2 0 1 0 0 0 1 4 0 0 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 290 R e 26.5 4qbz_A NAG SO4:MES 2 2 3 16 1 1 3 3 9 3 1 1 0 11 23 5 6 7 1 2 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 291 Y E e 37.0 4qbz_A UCG:06S beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. 2 0 2 14 6 3 6 4 6 9 2 3 1 2 4 11 7 7 2 10 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 292 L E b 1.7 4qbz_A 5 0 1 1 4 1 0 5 1 69 0 0 1 0 0 6 1 5 0 0 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 293 N E b 14.5 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. 2 0 17 2 1 5 7 4 2 1 1 24 0 4 4 10 2 9 1 3 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 294 L b 0.6 4qbz_A 3 2 0 0 5 0 0 8 0 60 3 4 0 0 0 2 5 5 1 0 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 295 S T b 0.0 4qbz_A 8 1 3 7 4 7 3 1 4 3 1 3 4 4 6 28 8 3 0 2 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 296 S T b 2.3 4qbz_A 2 0 9 6 2 16 4 2 2 1 3 15 2 5 8 16 3 1 0 4 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 297 T S b 0.0 4qbz_A 4 3 1 0 0 4 0 5 0 2 1 58 0 0 2 8 10 0 0 0 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 298 S b 0.0 4qbz_A 4 0 3 5 3 6 4 0 8 3 1 12 6 9 5 22 4 3 1 1 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 299 L b 0.6 4qbz_A 0 2 0 3 7 0 0 25 0 51 2 0 2 0 0 2 0 3 0 0 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 300 R S e 34.4 4qbz_A 2 0 4 8 1 4 1 2 9 2 2 5 1 7 14 17 12 3 0 4 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 301 K e 75.0 4qbz_A 3 3 3 4 4 33 4 3 6 3 3 4 3 3 4 5 6 3 2 3 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 302 I b 6.4 4qbz_A 3 0 3 6 3 3 0 17 3 24 3 3 3 3 3 4 5 9 0 3 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 303 N e 38.2 4qbz_A 7 2 8 7 3 5 4 9 4 5 2 7 16 3 2 8 4 3 0 0 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 304 A G e 20.5 4qbz_A 11 3 6 4 3 7 2 2 4 7 2 3 23 2 4 7 3 3 2 3 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 305 A G b 15.2 4qbz_A 5 2 7 4 2 18 4 3 4 4 2 7 4 3 4 14 8 3 0 3 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 306 W G b 6.0 4qbz_A 18 2 2 4 1 4 3 5 2 9 3 1 5 4 0 9 7 5 12 2 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 307 F G b 1.4 4qbz_A 1 1 0 0 46 1 0 10 0 23 2 1 4 0 0 0 2 3 2 0 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 308 K T e 56.1 4qbz_A SO4 7 3 4 9 1 11 5 1 11 2 1 3 3 9 9 12 2 3 1 2 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 309 N T e 28.5 4qbz_A NAG SO4 3 1 6 3 2 17 10 0 3 1 0 25 5 5 5 8 3 0 1 1 REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 7":TOPO_DOM:/note="Extracellular" 310 M b 1.0 4qbz_A 2 5 0 0 6 1 1 7 0 57 7 3 2 1 1 1 1 4 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 311 P T e 50.4 4qbz_A 6 0 1 3 1 4 3 2 11 3 1 6 26 6 6 9 7 2 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 312 H T e 28.8 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] MES 4 2 2 3 2 4 14 0 9 2 1 21 1 6 5 15 1 2 1 3 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 313 L b 1.7 4qbz_A 1 0 0 0 1 0 0 4 0 85 2 0 0 0 0 0 1 4 0 0 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 314 K e 30.2 4qbz_A UCG:06S SO4:MES 4 1 2 13 1 1 2 3 15 2 1 2 0 15 12 6 13 6 1 1 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 315 V E b 12.7 4qbz_A UCG:06S alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose.. 3 1 2 11 3 1 8 6 3 9 2 4 0 3 6 6 10 14 1 9 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 316 L E b 0.0 4qbz_A 2 2 0 0 3 0 0 8 0 75 0 0 0 0 1 1 0 7 0 0 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 317 D E b 8.0 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. 2 1 29 2 3 3 9 2 1 5 1 14 0 4 8 5 4 2 1 5 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 318 L b 0.6 4qbz_A 2 1 0 0 1 0 0 7 0 72 2 2 0 0 2 0 0 9 0 0 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 319 E T b 1.0 4qbz_A 5 1 9 12 3 3 2 1 2 2 1 2 1 9 5 35 1 2 1 4 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 320 F T e 25.8 4qbz_A UPT TLR8_HUMAN:Toll-like receptor 8[750 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[737 aa] 2 1 7 4 8 10 9 3 3 5 2 13 0 5 7 7 4 1 0 10 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 321 N S b 0.0 4qbz_A 1 2 2 2 2 1 1 0 0 2 1 77 2 1 1 3 0 0 0 2 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 322 Y e 31.3 4qbz_A 5 2 2 4 3 4 6 2 11 7 1 14 4 11 9 7 1 4 0 3 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 323 L T b 0.0 4qbz_A 3 0 1 2 9 2 0 11 1 52 1 2 1 1 1 4 1 6 0 1 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 324 V H b 18.0 4qbz_A 5 0 2 4 3 2 4 15 4 7 2 2 5 3 3 12 17 7 0 3 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 325 G H e 58.3 4qbz_A 5 0 4 4 1 37 1 3 5 4 0 7 4 3 3 10 6 2 0 1 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 326 E H b 12.1 4qbz_A 4 2 6 22 2 4 2 3 5 6 0 5 7 4 5 9 7 3 0 5 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 327 I H b 1.2 4qbz_A 4 0 2 1 5 2 0 36 2 16 2 2 4 0 2 3 4 16 1 1 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 328 A H e 30.4 4qbz_A NAG 12 0 2 3 2 5 3 7 3 5 1 1 27 2 1 11 8 6 0 0 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 329 S S e 52.3 4qbz_A NAG 7 3 6 10 2 4 1 1 3 5 0 5 14 3 2 21 6 3 1 1 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 330 G b 0.0 4qbz_A NAG 6 0 6 3 5 27 1 2 6 2 1 10 5 1 3 11 4 1 0 2 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 331 A G e 51.8 4qbz_A NAG 17 1 6 6 2 7 2 4 4 7 3 5 4 2 3 15 6 4 0 2 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 332 F G b 1.4 4qbz_A 6 2 1 3 34 5 2 3 2 9 1 4 2 2 2 7 4 3 2 5 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 333 L G b 0.0 4qbz_A 3 4 1 3 15 5 1 13 1 34 2 1 2 2 2 4 3 4 1 1 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 334 T G e 44.8 4qbz_A NAG 6 2 4 4 1 14 2 3 6 2 0 5 4 9 5 17 13 2 1 2 REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 8":TOPO_DOM:/note="Extracellular" 335 M G e 27.5 4qbz_A 4 0 2 6 6 14 4 3 3 8 8 12 5 4 3 8 3 4 2 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 336 L b 1.7 4qbz_A 1 4 0 3 5 2 0 6 1 55 4 2 1 3 0 3 2 4 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 337 P T e 51.2 4qbz_A 4 1 1 5 0 2 1 3 10 2 1 5 33 5 6 9 9 2 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 338 R T e 53.8 4qbz_A NAG TLR8_HUMAN:Toll-like receptor 8[747 aa] MES 3 1 3 3 1 4 3 2 9 4 1 18 3 9 15 14 4 1 1 1 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 339 L b 0.0 4qbz_A 0 1 0 0 1 1 0 5 1 76 2 2 0 0 0 3 0 4 1 0 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 340 E e 30.2 4qbz_A UCG:NAG:06S 4 0 1 22 1 2 4 3 14 2 2 2 3 12 12 5 6 5 1 0 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 341 I E e 36.3 4qbz_A UCG:06S 2 0 2 9 6 1 2 9 5 11 0 2 0 2 5 9 8 15 2 8 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 342 L E b 0.0 4qbz_A 0 0 0 1 2 1 0 4 0 76 2 1 0 1 0 2 0 5 0 1 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 343 D E b 5.6 4qbz_A UCG:06S 2 1 35 7 2 5 2 3 3 2 0 14 0 3 4 5 2 3 0 8 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 344 L b 1.1 4qbz_A 4 1 0 0 3 0 0 6 1 70 2 0 1 0 0 0 2 9 0 0 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 345 S T b 1.6 4qbz_A 7 1 3 3 1 8 3 3 2 1 0 6 0 3 2 49 4 1 1 3 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 346 F T e 22.0 4qbz_A C09:RX8:D87:D80:XG1:UPT:HB2:M0A:M4D:IDQ:MBL:CU8:7VF:7VL:DY3:O0W:U57:QLH:I6A:I5N:I5B:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 4 0 4 3 14 13 11 2 3 4 1 7 1 3 4 10 1 2 0 12 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 347 N b 0.6 4qbz_A 1 2 0 0 0 2 0 0 0 3 0 78 1 3 2 3 3 0 0 0 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 348 Y b 17.8 4qbz_A C09:L07:RX8:D87:D80:XG1:URI:HB2:M0A:M4D:IDQ:MBL:CU8:7VF:7VC:7VL:DY3:O0W:QSM:U57:QLH:GD0:I6A:I5N:I5B:RQY:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[736 aa] SO4 2 1 5 4 4 2 8 1 12 8 3 13 2 8 7 8 1 1 0 8 MUTAGEN:/note="Y->A: Abolishes activation of NF-kappa-B.":MUTAGEN:/note="Y->A: Abolishes responses to both ssRNA and chemical ligands.":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":MUTAGEN:/note="Y->A: Abolishes activation of NF-kappa-B.":MUTAGEN:/note="Y->A: Abolishes responses to both ssRNA and chemical ligands.":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 349 I e 54.4 4qbz_A RX8:URI:HB2:CU8:7VF:7VC:7VL:DY3:O0W:QSM:U57:QLH:GD0:I6A:I5N:RQY:JRI:YHG 1 1 0 1 12 0 2 31 1 40 0 0 2 1 1 2 0 3 0 1 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 350 K T e 64.6 4qbz_A URI:HB2:CU8:7VF:7VC:7VL:DY3:O0W:QSM:U57:QLH:NAG:GD0:I6A:I5N:I5B:RQY:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[744 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[749 aa] SO4 3 0 3 10 2 4 3 2 12 4 1 2 2 4 8 19 14 5 0 2 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 351 G T e 100.0 4qbz_A RX8:URI:HB2:M8D:M0A:M4D:IDQ:CU8:7VF:7VC:7VL:DY3:O0W:QSM:U57:QLH:GD0:I6A:I5N:I5B:RQY:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[733 aa]:Toll-like receptor 8[736 aa]:Toll-like receptor 8[749 aa] SO4 4 1 3 3 2 38 1 3 6 7 1 2 5 3 3 10 4 2 0 2 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 352 S e 38.3 4qbz_A RX8:URI:HB2:M8D:M0A:M4D:IDQ:CU8:7VF:7VC:7VL:DY3:O0W:QSM:QLH:GD0:I6A:I5N:RQY:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[733 aa]:Toll-like receptor 8[749 aa] 7 1 6 8 3 4 2 7 2 7 3 8 4 3 2 17 6 8 1 2 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 353 Y e 30.4 4qbz_A C09:L07:RX8:D87:D80:XG1:URI:HB2:M8D:M0A:M4D:IDQ:MBL:U57 TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[733 aa]:Toll-like receptor 8[736 aa]:Toll-like receptor 8[749 aa] SO4 3 0 2 5 5 2 3 20 2 20 2 3 3 1 2 7 3 6 0 8 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 354 P e 34.1 4qbz_A SO4 5 0 2 2 4 2 2 3 2 6 1 3 54 1 2 3 1 4 0 2 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 355 Q S e 53.6 4qbz_A SO4 9 1 6 10 2 4 4 2 5 4 1 4 9 12 7 11 3 3 1 1 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 356 H S e 28.3 4qbz_A SO4 7 2 6 7 4 6 13 4 4 6 1 5 2 3 5 13 4 5 1 3 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 357 I b 1.8 4qbz_A 4 1 3 2 8 2 1 16 3 33 3 2 1 2 2 2 3 10 1 2 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 358 N e 59.4 4qbz_A 5 2 5 5 4 12 4 2 8 4 1 16 5 3 7 7 4 3 0 1 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 359 I b 5.8 4qbz_A 3 2 3 4 5 5 2 14 4 17 2 3 5 4 4 5 6 7 2 3 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 360 S b 7.8 4qbz_A NAG 7 5 2 5 2 5 2 4 2 9 2 4 9 2 3 26 7 3 0 1 REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 9":TOPO_DOM:/note="Extracellular" 361 R G e 79.4 4qbz_A NAG 6 1 2 8 1 6 3 3 8 9 1 5 6 4 19 9 4 3 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 362 N G e 26.1 4qbz_A NAG 8 1 4 2 1 7 1 2 5 6 1 26 3 3 2 15 7 2 0 4 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular" 363 F G b 0.5 4qbz_A 2 1 1 1 42 2 2 4 1 27 1 2 1 2 2 3 3 2 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 364 S G e 41.4 4qbz_A 6 2 4 8 2 9 2 1 4 9 0 4 3 6 5 22 8 1 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 365 K G e 45.3 4qbz_A SO4 3 0 8 7 0 19 6 1 11 4 0 10 3 4 4 13 2 2 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 366 L b 0.0 4qbz_A 3 4 1 2 4 2 1 4 1 52 4 2 1 2 2 1 4 5 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 367 L T e 56.7 4qbz_A NAG 2 0 1 2 2 5 2 8 4 29 1 2 6 4 3 6 13 10 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 368 S T e 29.7 4qbz_A NAG 8 1 4 8 2 5 4 1 10 4 0 16 1 4 3 22 3 3 0 3 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 369 L b 0.0 4qbz_A 1 1 1 2 3 1 0 5 1 71 0 2 1 0 1 1 1 4 1 2 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 370 R e 43.1 4qbz_A NAG:UCG:06S 5 0 2 14 2 3 2 1 11 2 1 4 2 14 16 10 7 3 1 1 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 371 A E b 9.8 4qbz_A 9 1 1 10 3 4 6 8 7 6 1 5 1 4 4 14 5 8 1 4 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 372 L E b 0.0 4qbz_A 3 1 0 2 4 0 1 4 1 60 1 12 0 1 1 1 2 4 1 1 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 373 H E b 18.8 4qbz_A UCG:06S 4 0 15 5 2 2 15 1 3 5 2 11 2 3 6 9 5 3 1 6 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 374 L b 0.0 4qbz_A 1 0 1 0 5 1 0 8 0 62 3 2 0 2 0 5 1 6 0 0 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 375 R T e 24.1 4qbz_A UCG:06S:UPT SO4:FMT 4 0 6 6 1 6 5 2 6 5 1 7 2 7 10 19 6 3 0 3 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 376 G T b 2.4 4qbz_A C09:RX8:D80:XG1:HB2:M0A:M4D:IDQ:MBL:CU8:7VF:7VC:7VL:QLH:I6A:I5N:I5B:JRI:YHG 4 1 8 3 1 41 6 2 2 2 1 12 1 1 2 7 2 1 0 2 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 377 Y b 4.8 4qbz_A 2 0 2 3 6 2 2 4 2 8 1 36 1 4 1 7 3 3 3 8 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 378 V b 16.0 4qbz_A C09:L07:RX8:D87:D80:XG1:URI:HB2:M8D:M0A:M4D:IDQ:MBL:CU8:7VF:7VC:7VL:DY3:O0W:QSM:U57:QLH:GD0:I6A:I5N:I5B:RQY:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[733 aa]:Toll-like receptor 8[736 aa]:Toll-like receptor 8[749 aa] 8 1 3 4 5 3 3 12 10 10 2 3 2 8 3 9 4 9 1 2 MUTAGEN:/note="V->A: Increases activation of NF-kappa-B.":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":MUTAGEN:/note="V->A: Increases activation of NF-kappa-B.":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 379 F b 0.0 4qbz_A 1 1 1 1 19 1 2 19 1 23 1 2 11 3 2 2 1 4 1 4 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 380 Q S e 20.9 4qbz_A TLR8_HUMAN:Toll-like receptor 8[751 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[749 aa] 3 0 2 9 1 6 3 1 5 8 2 11 5 16 5 11 8 1 1 2 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 381 E E e 25.6 4qbz_A 4 2 5 23 1 7 3 1 3 2 0 7 2 7 4 15 5 3 1 2 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 382 L E b 0.0 4qbz_A 2 1 1 1 2 1 0 24 1 43 3 2 1 0 3 3 3 7 0 1 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 383 R e 38.7 4qbz_A 5 2 2 7 2 10 4 3 9 3 1 5 9 3 13 8 5 3 0 5 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 384 E G e 20.6 4qbz_A NAG 4 4 11 9 3 8 3 3 7 4 0 5 9 5 5 9 4 4 0 3 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 385 D G e 72.8 4qbz_A 4 0 9 6 3 7 3 4 7 10 3 9 3 3 4 6 10 4 3 3 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 386 D G b 9.9 4qbz_A 9 0 18 4 4 4 4 6 3 5 4 5 4 4 0 8 13 5 0 0 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 387 F G b 0.0 4qbz_A 3 2 2 2 32 2 0 5 3 17 4 4 7 0 0 4 2 5 3 3 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 388 Q G e 39.8 4qbz_A NAG 6 2 3 8 4 6 3 3 4 4 1 3 5 16 8 16 4 2 0 0 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 389 P G b 13.2 4qbz_A 6 1 4 4 3 13 2 4 3 4 2 1 25 2 2 10 4 8 1 1 REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 10":TOPO_DOM:/note="Extracellular" 390 L G b 0.0 4qbz_A 2 2 1 3 8 2 1 11 2 48 1 1 2 2 1 2 2 6 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 391 M T b 3.9 4qbz_A NAG 7 1 2 2 6 10 6 4 5 12 4 1 1 6 5 7 6 11 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 392 Q T e 90.3 4qbz_A NAG 4 0 3 9 2 8 7 2 5 4 2 13 2 19 4 7 2 2 1 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 393 L b 2.2 4qbz_A 2 4 1 1 3 2 0 4 2 53 5 2 1 3 2 4 2 4 2 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 394 P T e 55.0 4qbz_A NAG 4 0 4 7 1 5 4 2 12 5 0 3 26 7 3 5 6 5 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 395 N T e 44.2 4qbz_A NAG 4 1 5 8 1 5 6 1 6 4 2 25 1 5 5 15 3 1 0 2 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 396 L b 0.6 4qbz_A 0 0 3 0 2 0 0 6 0 74 1 2 0 0 0 0 4 5 0 0 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 397 S e 28.9 4qbz_A 3 1 3 11 1 2 2 3 5 5 0 10 2 8 12 18 9 3 2 1 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 398 T E b 11.0 4qbz_A 3 1 3 5 5 1 3 9 4 13 2 4 0 2 4 9 18 8 1 5 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 399 I E b 0.0 4qbz_A 3 1 3 4 3 3 0 12 2 45 3 3 2 0 0 6 2 7 0 0 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 400 N E b 1.8 4qbz_A UCG:06S 6 0 21 3 2 4 6 2 2 6 1 17 0 5 6 10 3 3 1 3 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 401 L b 0.0 4qbz_A 1 0 3 2 3 0 2 12 2 60 2 2 0 0 0 4 2 4 0 0 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 402 G b 0.0 4qbz_A 6 0 5 6 2 18 4 0 2 7 2 6 3 6 6 20 2 2 1 2 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 403 I S e 26.9 4qbz_A C09:RX8:D80:UPT:HB2:M8D:M4D:MBL:CU8:7VF:7VC:7VL:DY3:O0W:QLH:I5N:I5B:RQY:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 2 1 6 4 2 7 7 11 2 16 3 7 0 5 5 6 5 6 1 5 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 404 N S b 0.0 4qbz_A 2 2 11 0 0 2 0 2 2 1 0 61 0 4 2 4 2 3 0 0 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 405 F e 46.4 4qbz_A C09:L07:RX8:D87:D80:XG1:URI:HB2:M8D:M0A:M4D:IDQ:MBL:CU8:7VF:7VC:7VL:DY3:O0W:QSM:U57:QLH:GD0:I6A:I5N:I5B:RQY:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[733 aa]:Toll-like receptor 8[736 aa] 2 0 2 2 16 5 4 6 8 11 2 6 2 6 9 10 4 2 1 4 MUTAGEN:/note="F->A: Abolishes activation of NF-kappa-B.":MUTAGEN:/note="F->A: Abolishes responses to both ssRNA and chemical ligands.":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":MUTAGEN:/note="F->A: Abolishes activation of NF-kappa-B.":MUTAGEN:/note="F->A: Abolishes responses to both ssRNA and chemical ligands.":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 406 I b 0.0 4qbz_A 1 2 0 0 5 2 0 35 0 27 2 0 4 0 0 3 6 5 0 5 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 407 K e 38.7 4qbz_A TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[733 aa]:Toll-like receptor 8[736 aa]:Toll-like receptor 8[749 aa] 4 2 3 10 1 5 1 1 10 1 1 5 6 8 9 16 13 2 0 1 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 408 Q E e 55.1 4qbz_A TLR8_HUMAN:Toll-like receptor 8[733 aa] 4 1 3 8 2 14 2 4 4 3 2 5 7 7 6 17 6 3 1 1 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 409 I E b 10.5 4qbz_A 3 2 0 2 3 5 1 26 5 23 2 2 3 2 2 4 3 9 0 1 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 410 D e 37.7 4qbz_A 6 0 15 10 2 4 3 9 2 3 1 4 16 4 3 10 4 3 1 0 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 411 F G b 8.1 4qbz_A 8 2 4 4 19 2 1 1 5 12 1 3 19 2 4 3 2 4 1 3 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 412 K G e 41.5 4qbz_A NAG 6 1 4 8 1 12 3 2 16 7 1 10 4 3 7 9 2 4 0 1 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 413 L G b 0.0 4qbz_A 14 1 3 7 5 3 0 9 1 16 4 2 2 2 1 14 6 6 2 0 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 414 F G b 1.4 4qbz_A 0 1 0 0 46 2 1 11 0 20 1 0 2 1 2 2 1 2 2 5 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 415 Q G e 56.1 4qbz_A NAG 8 1 4 9 1 11 4 2 3 4 1 6 3 18 9 11 3 1 1 2 REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 416 N G e 58.2 4qbz_A NAG 5 2 14 2 1 13 4 1 5 1 0 23 5 3 3 9 2 2 1 2 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 11":TOPO_DOM:/note="Extracellular" 417 F S b 6.7 4qbz_A 4 7 1 1 15 1 0 7 2 38 3 0 2 2 1 3 4 7 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 418 S S e 50.0 4qbz_A 3 0 4 2 0 8 4 1 12 2 1 4 10 2 8 22 14 1 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 419 N e 45.5 4qbz_A 5 1 6 2 3 4 6 0 9 5 1 24 0 4 5 18 3 3 0 1 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 420 L b 2.8 4qbz_A 1 0 0 1 1 1 1 6 2 74 1 1 0 1 1 2 2 3 0 0 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 421 E S e 32.2 4qbz_A 2 0 2 22 1 1 7 2 9 2 1 6 0 9 15 8 7 5 0 0 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 422 I E e 21.1 4qbz_A 3 0 2 7 7 1 3 7 2 13 2 3 2 1 3 9 14 12 3 7 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 423 I E b 1.2 4qbz_A 2 0 0 0 8 2 0 12 0 57 3 1 0 0 0 0 4 9 0 0 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 424 Y E b 8.3 4qbz_A 3 0 23 4 6 2 9 3 1 6 1 11 1 2 4 6 3 2 2 12 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 425 L b 0.0 4qbz_A 2 0 0 2 5 2 1 5 0 62 4 0 0 1 3 0 2 8 0 1 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 426 S b 4.7 4qbz_A NAG beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. 12 1 5 6 1 6 3 1 4 1 0 5 1 6 3 37 4 2 1 2 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 427 E S e 46.7 4qbz_A O0W:QSM:I5N:I5B:RQY:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 2 1 9 13 2 10 5 1 5 4 0 20 0 8 3 8 2 3 0 3 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 428 N S b 6.1 4qbz_A 5 1 3 1 4 2 1 1 1 0 0 68 1 2 3 7 0 0 0 0 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 429 R e 43.5 4qbz_A C09:RX8:D80:XG1:URI:HB2:M8D:M0A:IDQ:MBL TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[744 aa] 5 0 1 8 4 4 4 2 7 2 2 15 2 6 25 9 1 1 0 1 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 430 I b 1.8 4qbz_A 1 2 0 1 12 1 0 27 1 36 1 1 0 0 0 5 2 4 2 1 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 431 S e 41.4 4qbz_A TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[733 aa]:Toll-like receptor 8[736 aa] 5 2 2 6 1 6 1 1 6 4 2 5 2 4 5 32 16 2 0 0 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 432 P e 20.9 4qbz_A TLR8_HUMAN:Toll-like receptor 8[752 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[749 aa] 8 4 4 8 2 23 2 1 2 2 0 2 15 2 2 9 5 6 1 2 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" P->L:LP/P:-: Immunodeficiency 98 with autoinflammation, X-linked (IMD98) ; 433 L e 47.2 4qbz_A 4 0 3 4 3 4 1 11 2 29 4 2 4 4 3 6 4 11 0 2 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 434 V e 110.7 4qbz_A TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[749 aa] 7 0 1 3 4 3 4 20 2 12 4 2 9 3 2 4 4 15 0 1 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 435 K e 102.4 3w3g_A 4 3 4 6 2 5 1 1 16 4 2 4 25 5 6 3 4 2 1 1 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 436 D e 75.9 7crf_B 4 0 23 8 4 12 3 4 4 4 1 4 3 2 4 9 5 2 1 1 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 437 T e 82.5 7ytx_B 6 10 2 3 3 5 2 5 4 14 2 4 1 3 1 12 15 6 1 2 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 438 R 5 1 4 5 9 5 1 9 7 14 1 3 4 3 16 5 2 4 0 1 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 439 Q 5 4 7 12 4 7 2 3 3 6 0 6 5 11 6 8 5 4 1 1 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 440 S 6 2 3 3 3 17 0 4 3 8 2 5 2 3 2 29 6 1 0 0 REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 12":TOPO_DOM:/note="Extracellular" 441 Y 3 3 2 1 12 5 4 6 2 23 1 3 2 3 1 3 3 4 3 14 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 442 A 17 2 2 4 3 10 1 10 2 12 1 4 5 1 2 9 4 9 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 443 N e 78.8 5hdh_A 5 1 6 6 2 11 2 2 8 7 2 26 2 3 4 7 3 3 0 1 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular" 444 S e 87.5 5hdh_A 3 3 3 3 2 4 2 5 3 21 3 4 3 3 2 20 8 6 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 445 S B e 53.9 5hdh_A 5 3 5 4 2 11 2 3 3 6 2 8 3 6 4 17 5 4 3 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 446 S e 31.2 5hdh_A 3 0 6 5 3 11 4 5 6 11 0 7 3 4 4 14 4 6 3 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 447 F e 76.1 5hdh_A 4 2 0 2 16 6 4 6 3 22 5 4 4 0 3 5 0 5 3 5 TOPO_DOM:/note="Extracellular":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Extracellular" 448 Q b 19.9 5hdh_A 5 2 3 9 3 3 4 3 9 7 1 7 9 17 6 5 3 2 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 449 R e 65.2 5hdh_A 4 2 3 6 2 7 1 2 5 19 0 8 2 5 12 8 4 5 2 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 450 H e 23.6 5hdh_A 4 2 3 7 3 4 15 4 5 11 3 6 2 5 4 11 2 3 3 4 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 451 I e 100.0 5hdh_A 5 3 2 3 3 2 1 18 1 29 2 3 2 1 2 5 2 11 1 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 452 R 5 1 5 6 2 6 4 3 8 14 1 8 7 3 13 8 3 1 1 1 MUTAGEN:/note="RKRR->NQSN: Monomeric and inactive.":TOPO_DOM:/note="Extracellular":MUTAGEN:/note="RKRR->NQSN: Monomeric and inactive.":TOPO_DOM:/note="Extracellular" 453 K 4 1 4 8 1 7 2 3 13 10 0 9 4 7 6 9 4 5 0 2 MUTAGEN:/note="RKRR->NQSN: Monomeric and inactive.":TOPO_DOM:/note="Extracellular":MUTAGEN:/note="RKRR->NQSN: Monomeric and inactive.":TOPO_DOM:/note="Extracellular" 454 R 3 1 3 3 3 5 2 5 8 21 1 9 2 5 13 4 4 6 0 1 MUTAGEN:/note="RKRR->NQSN: Monomeric and inactive.":TOPO_DOM:/note="Extracellular":MUTAGEN:/note="RKRR->NQSN: Monomeric and inactive.":TOPO_DOM:/note="Extracellular" 455 R 3 0 4 6 4 6 2 3 7 12 2 3 4 9 17 8 4 4 0 2 MUTAGEN:/note="RKRR->NQSN: Monomeric and inactive.":TOPO_DOM:/note="Extracellular":MUTAGEN:/note="RKRR->NQSN: Monomeric and inactive.":TOPO_DOM:/note="Extracellular" 456 S 3 2 2 7 6 8 1 7 3 16 0 6 3 1 2 22 7 4 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 457 T e 65.6 4qbz_A TLR8_HUMAN:Toll-like receptor 8[748 aa] 7 1 2 6 2 5 0 8 5 11 1 9 4 2 2 8 17 9 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 458 D e 75.3 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[748 aa] 6 0 22 11 1 7 0 3 8 10 2 5 4 2 2 6 4 3 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 459 F e 21.5 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa] 3 1 2 5 25 8 1 6 3 23 3 2 2 1 2 3 4 3 1 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 460 E S e 73.9 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 5 0 11 20 2 5 2 3 3 5 0 3 5 6 6 10 6 4 0 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 461 F S e 20.1 4qbz_A TLR8_HUMAN:Toll-like receptor 8[750 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[737 aa] 2 3 3 2 24 5 1 8 3 22 1 2 1 2 2 5 3 5 2 4 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 462 D e 52.5 4qbz_A MAN alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 4 3 21 6 3 6 1 5 6 9 1 6 2 4 3 10 2 7 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 463 P T b 17.8 4qbz_A alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(.. SO4 7 1 4 8 3 6 1 2 3 8 1 9 23 3 1 7 5 4 2 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 464 H T e 60.2 4qbz_A MAN beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. SO4 5 1 2 12 3 4 19 3 3 10 1 3 4 4 3 12 3 5 1 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 465 S S e 48.4 4qbz_A MAN beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. 5 2 5 7 2 7 1 2 5 11 1 9 6 4 6 15 5 6 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 466 N e 35.8 4qbz_A 06S beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. GOL 2 0 5 8 1 8 2 2 9 5 0 35 2 5 3 4 7 2 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 467 F S b 17.7 4qbz_A UPT beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. FMT 3 1 4 1 17 3 1 7 2 25 2 3 2 1 4 5 4 5 1 5 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 468 Y S b 9.6 4qbz_A UPT beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(2-3)-[beta-D-mannopyranose-..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. FMT 6 1 2 8 12 6 1 7 4 19 0 1 4 4 3 4 6 3 3 4 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 469 H S e 26.7 4qbz_A UCG:06S:UPT SO4:FMT 4 2 6 8 2 6 13 2 7 6 2 9 1 2 7 11 5 4 1 4 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 470 F e 79.9 4qbz_A UCG:06S:UPT SO4:FMT 5 0 1 3 28 10 2 4 2 15 1 3 1 2 2 6 2 3 1 6 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 471 T e 69.5 4qbz_A UCG:06S GOL 5 1 8 4 1 2 0 8 5 9 1 5 6 5 1 11 20 5 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 472 R S e 67.6 4qbz_A UCG:06S beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. 2 0 4 2 2 7 2 9 6 9 0 7 5 3 20 9 4 4 2 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 473 P e 62.8 4qbz_A UCG 7 0 4 3 2 5 0 2 2 7 2 8 26 3 3 13 5 4 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 474 L S e 25.8 4qbz_A UCG:06S 6 1 2 5 4 2 2 11 1 34 4 5 2 2 2 4 3 8 2 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 475 I S b 5.8 4qbz_A NAG beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. 4 6 2 5 5 4 1 13 2 19 1 3 2 2 1 8 6 14 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 476 K e 54.2 4qbz_A NAG beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 5 1 2 17 1 5 1 7 15 10 3 3 8 3 5 5 3 3 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 477 P H e 57.4 4qbz_A 3 1 4 5 3 14 1 3 4 8 1 4 26 3 2 7 6 5 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 478 Q H e 57.1 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 4 0 3 12 3 3 1 3 10 11 1 9 3 11 9 8 5 1 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 479 C H b 4.7 4qbz_A NAG beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. 5 26 3 3 4 7 1 6 2 13 1 2 2 3 2 5 8 3 1 2 DISULFID::TOPO_DOM:/note="Extracellular":DISULFID::TOPO_DOM:/note="Extracellular" 480 A H e 27.7 4qbz_A 13 0 3 5 4 5 1 4 7 10 1 5 3 3 7 11 8 4 0 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 481 A T e 78.6 4qbz_A 15 5 3 8 6 7 3 2 5 8 3 2 2 2 7 12 6 4 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 482 Y T e 31.7 4qbz_A NAG 3 2 3 6 7 4 3 4 3 20 2 6 3 2 3 6 5 5 2 13 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 483 G S e 29.8 4qbz_A NAG 5 1 5 2 2 26 2 3 3 11 4 4 3 2 3 6 8 8 1 1 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 484 K e 27.8 4qbz_A 4 0 5 11 2 3 2 2 21 5 1 4 3 9 10 7 7 2 0 2 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 485 A E b 0.0 4qbz_A 9 1 2 8 4 4 2 7 3 9 3 3 4 2 5 9 13 11 1 2 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 486 L E b 0.6 4qbz_A 2 0 1 3 5 1 0 8 0 60 3 1 0 1 3 2 5 5 0 0 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 487 D E b 3.1 4qbz_A NAG beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. 2 1 47 6 2 2 2 1 3 3 0 11 0 1 4 5 6 2 0 3 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 488 L b 0.0 4qbz_A 1 3 2 2 4 1 1 8 0 64 2 0 0 1 2 1 1 6 0 3 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 489 S b 6.2 4qbz_A NAG beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. 7 1 4 4 1 4 1 1 3 0 1 5 0 5 6 45 9 0 0 3 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 490 L S e 41.6 4qbz_A NAG:YHG beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 5 1 5 3 5 6 4 5 6 15 4 12 0 5 9 5 2 1 1 6 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 491 N S b 6.1 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 1 1 6 1 2 1 1 2 3 2 0 67 1 1 3 4 3 1 0 0 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 492 S e 42.2 4qbz_A TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[736 aa] 4 0 5 8 1 4 3 0 10 4 1 17 4 7 10 14 3 0 1 5 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 493 I b 0.6 4qbz_A 1 1 0 2 8 1 0 38 0 31 1 3 0 0 1 0 0 10 0 1 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 494 F e 55.5 4qbz_A CU8:7VF:7VC:7VL:DY3:O0W:QSM:QLH:GD0:I6A:I5N:I5B:RQY:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[733 aa]:Toll-like receptor 8[736 aa] 4 0 2 5 9 6 3 4 5 6 1 4 3 3 6 19 14 5 0 1 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" F->L:LP/P:-: Immunodeficiency 98 with autoinflammation, X-linked (IMD98) ; 495 F S e 47.8 4qbz_A CU8:7VF:7VC:7VL:DY3:O0W:QSM:QLH:GD0:I6A:I5N:I5B:RQY:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[733 aa]:Toll-like receptor 8[736 aa]:Toll-like receptor 8[749 aa] 3 0 4 6 13 25 3 3 6 7 0 3 0 4 2 7 5 2 1 6 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 496 I b 1.8 4qbz_A 3 1 1 6 2 2 0 25 2 23 1 2 4 3 1 3 5 15 1 0 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 497 G b 17.9 4qbz_A 6 0 3 6 2 18 1 15 5 4 1 2 8 6 2 9 3 4 2 3 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 498 P T e 89.9 4qbz_A TLR8_HUMAN:Toll-like receptor 8[737 aa]:Toll-like receptor 8[750 aa] 6 0 3 6 2 3 2 3 2 2 0 4 49 2 3 9 2 1 0 1 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 499 N T e 52.7 4qbz_A 3 0 8 10 3 10 2 4 6 1 1 20 2 3 3 14 4 3 0 1 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 500 Q T b 2.6 4qbz_A 16 3 1 15 3 4 3 2 3 6 2 3 4 6 4 12 6 2 4 1 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 501 F T b 2.4 4qbz_A 2 0 0 1 45 1 0 15 2 21 1 0 1 0 0 2 1 3 1 2 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 502 E T e 49.2 4qbz_A 6 0 7 11 4 11 4 2 8 3 2 3 2 4 6 13 5 4 5 1 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 503 N T e 46.7 4qbz_A 3 3 11 4 1 16 4 1 7 1 1 16 1 4 4 12 7 2 1 2 REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 13":TOPO_DOM:/note="Extracellular" 504 L b 8.4 4qbz_A 3 3 1 0 5 1 0 8 1 59 5 1 0 1 0 1 2 4 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 505 P b 13.2 4qbz_A 5 0 4 4 1 3 1 1 5 4 1 5 33 2 8 12 7 4 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 506 D e 59.3 4qbz_A NAG 3 0 13 9 3 5 4 1 7 4 0 18 2 6 6 10 4 1 1 2 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 507 I b 0.0 4qbz_A 1 1 1 0 2 0 0 12 1 62 1 0 0 0 0 4 5 7 0 0 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 508 A S b 6.2 4qbz_A NAG 7 1 3 13 2 6 2 2 8 3 1 3 1 11 11 9 10 4 0 2 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 509 C E b 1.3 4qbz_A 4 8 3 11 4 1 3 4 9 11 1 2 0 1 6 12 7 7 1 4 REPEAT:/note="LRR 14":DISULFID::TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":DISULFID::TOPO_DOM:/note="Extracellular" 510 L E b 0.0 4qbz_A 2 1 2 1 4 0 0 7 0 65 2 0 2 1 1 1 1 7 0 2 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 511 N E b 18.2 4qbz_A NAG beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. 2 0 24 3 1 4 5 2 2 4 0 25 3 1 5 8 4 3 1 3 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 512 L b 3.4 4qbz_A 1 4 0 1 4 1 0 7 0 66 3 0 1 0 1 1 1 7 0 0 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 513 S b 12.5 4qbz_A NAG beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. 8 1 4 3 2 3 1 1 3 2 1 6 1 6 4 41 5 3 1 4 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 514 A S e 22.3 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 10 2 4 6 3 12 9 1 4 6 0 9 0 2 6 14 1 2 0 6 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 515 N S b 0.6 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa]:Toll-like receptor 8[749 aa] 1 1 0 1 1 2 0 3 3 2 1 73 1 2 3 2 3 1 0 0 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 516 S e 46.9 4qbz_A DY3:O0W:QSM:QLH:I6A:I5N:I5B:RQY:YHG TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa] 5 2 4 5 1 7 6 3 8 4 2 12 2 8 7 12 6 2 0 3 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 517 N b 3.0 4qbz_A 2 0 5 2 7 5 2 20 3 18 2 13 2 5 3 5 1 4 0 1 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 518 A e 30.4 4qbz_A CU8:7VF:7VC:7VL:DY3:O0W:QSM:QLH:GD0:I6A:I5N:I5B:RQY:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[747 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 9 0 1 4 2 7 1 10 5 13 1 1 6 3 4 15 12 4 0 2 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 519 Q b 6.6 4qbz_A CU8:7VF:7VC:7VL:DY3:O0W:QSM:GD0:JRI:YHG TLR8_HUMAN:Toll-like receptor 8[746 aa] 3 1 2 14 1 9 3 2 7 4 2 5 1 16 8 10 4 4 1 2 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 520 V e 34.0 4qbz_A RX8:URI:M4D:MBL:CU8:7VF:7VC:7VL:DY3:O0W:U57:GD0 TLR8_HUMAN:Toll-like receptor 8[747 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[751 aa] 5 0 2 5 6 3 1 15 3 15 1 1 1 1 2 9 10 19 0 2 MUTAGEN:/note="V->A: Strongly decreases activation of NF-kappa-B.":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":MUTAGEN:/note="V->A: Strongly decreases activation of NF-kappa-B.":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 521 L b 2.2 4qbz_A 2 2 1 4 7 1 0 11 2 35 4 1 8 0 3 3 1 11 0 2 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 522 S e 32.8 4qbz_A NAG 5 1 5 8 1 9 2 2 4 5 0 5 13 2 3 15 11 5 1 1 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 523 G S b 17.9 4qbz_A 7 1 3 5 4 36 2 1 4 2 1 7 10 1 4 5 1 3 0 4 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 524 T e 57.8 4qbz_A NAG 10 2 9 9 2 4 1 1 4 6 1 6 6 3 6 12 9 4 0 3 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 525 E T b 11.6 4qbz_A 6 3 12 17 4 3 2 3 6 5 1 6 5 5 4 8 3 5 0 1 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 526 F T b 0.0 4qbz_A 1 1 2 1 41 2 0 10 1 23 3 1 3 1 1 1 2 3 1 1 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 527 S T e 54.7 4qbz_A 9 1 2 5 3 12 3 2 7 5 1 2 2 5 6 19 9 4 1 1 REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 14":TOPO_DOM:/note="Extracellular" 528 A T e 47.3 4qbz_A 9 1 4 3 2 20 3 1 6 6 0 9 3 4 3 13 6 3 0 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 529 I S b 1.2 4qbz_A 3 5 1 0 5 1 1 16 0 44 3 1 1 2 2 3 4 6 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 530 P T e 33.3 4qbz_A 6 0 2 2 1 5 1 1 10 2 1 1 33 4 6 10 9 3 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 531 H T e 42.9 4qbz_A 5 3 4 3 2 4 12 1 6 4 0 14 3 9 7 16 4 1 0 2 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 532 V b 0.0 4qbz_A 1 2 0 1 3 2 1 7 0 62 3 2 3 0 0 0 3 8 1 1 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 533 K e 26.9 4qbz_A NAG 2 0 1 11 0 2 3 2 21 3 2 2 0 9 23 5 9 2 0 2 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 534 Y E b 6.1 4qbz_A NAG beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 4 0 2 7 6 1 5 5 4 8 1 3 0 2 6 8 7 11 3 17 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 535 L E b 0.0 4qbz_A 0 1 0 3 4 0 0 8 2 70 2 0 1 1 0 1 0 7 1 0 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 536 D E b 14.8 4qbz_A NAG beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(.. 1 0 32 5 3 1 6 4 1 2 2 12 0 3 5 9 6 2 1 5 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 537 L b 1.1 4qbz_A 2 2 0 0 4 1 0 10 0 66 4 0 0 1 0 1 1 5 1 0 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 538 T b 8.4 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-.. 5 0 3 4 2 5 2 2 2 0 1 5 2 6 5 36 12 5 1 3 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 539 N S e 46.1 4qbz_A 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. 4 0 4 6 2 11 15 3 5 1 1 25 0 2 6 6 2 1 0 7 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 540 N S b 7.3 4qbz_A 1 4 0 0 3 1 0 2 3 1 1 74 0 0 2 3 3 2 0 0 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 541 R e 45.5 4qbz_A O0W:QSM:I6A:I5N:RQY:YHG TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 4 1 2 3 1 4 5 2 19 5 2 7 1 11 18 5 4 3 1 3 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 542 L b 1.1 4qbz_A 0 2 0 2 11 0 0 21 0 49 3 1 0 0 0 2 0 5 0 0 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 543 D b 18.5 4qbz_A C09:L07:RX8:D80:XG1:URI:HB2:M8D:M0A:M4D:IDQ:MBL:U57:GD0 TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 5 1 10 11 4 3 4 2 5 1 1 2 0 7 7 19 15 3 1 1 MUTAGEN:/note="D->A: Abolishes activation of NF-kappa-B." ECO:0000269|PubMed:33512449":MUTAGEN:/note="D->A: Abolishes responses to both ssRNA and chemical ligands.":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":MUTAGEN:/note="D->A: Abolishes activation of NF-kappa-B." ECO:0000269|PubMed:33512449":MUTAGEN:/note="D->A: Abolishes responses to both ssRNA and chemical ligands.":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 544 F b 4.8 4qbz_A 4 1 2 3 12 23 2 4 3 11 2 5 1 2 2 7 3 4 1 9 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 545 D e 36.4 4qbz_A C09:L07:RX8:D80:XG1:URI:HB2:M8D:M0A:M4D:IDQ:MBL:NAG:U57 SO4 2 0 9 9 3 2 1 12 4 14 1 4 4 6 2 9 3 12 1 2 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 546 N e 33.3 4qbz_A NAG 2 0 6 4 2 4 5 15 2 10 1 12 12 4 4 8 2 4 2 0 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 547 A T e 39.3 4qbz_A NAG 12 3 4 6 3 6 1 2 1 5 1 5 31 2 1 11 2 4 0 1 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 548 S T e 46.1 4qbz_A NAG 8 1 6 7 3 12 1 1 6 6 1 5 4 4 6 18 4 2 2 2 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 549 A T b 1.8 4qbz_A 20 2 3 4 3 5 3 5 3 8 2 1 1 3 3 14 8 10 1 0 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 550 L T b 0.0 4qbz_A 0 3 0 2 25 1 5 12 2 30 4 0 1 2 0 2 1 4 1 4 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 551 T T e 26.0 4qbz_A NAG 5 4 6 5 3 12 2 1 7 1 1 3 1 6 5 12 15 7 1 3 REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 15":TOPO_DOM:/note="Extracellular" 552 E T b 14.1 4qbz_A 4 1 8 11 1 9 3 2 10 5 1 13 4 8 6 7 3 2 2 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 553 L b 0.0 4qbz_A 2 3 0 2 4 1 1 7 0 57 4 1 1 1 2 2 2 3 1 5 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 554 S T e 57.8 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] 6 3 2 4 1 5 2 3 4 2 0 6 12 4 6 22 11 4 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 555 D T e 33.3 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] 6 1 14 12 2 4 3 1 7 2 1 11 2 8 6 14 4 1 0 1 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 556 L b 0.0 4qbz_A 3 0 0 0 2 1 0 7 0 67 2 4 1 2 3 2 3 4 0 0 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 557 E b 18.1 4qbz_A 3 0 2 23 1 1 2 3 9 1 1 6 5 13 11 5 5 5 1 3 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 558 V E b 10.0 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 4 1 2 7 5 1 4 10 5 8 1 1 2 1 4 7 17 11 2 6 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 559 L E b 0.6 4qbz_A 2 0 2 0 2 0 0 4 2 68 3 0 2 3 2 0 0 7 0 0 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 560 D E b 13.6 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 3 4 32 9 1 1 1 7 3 2 4 8 1 3 4 6 4 3 1 5 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 561 L b 0.0 4qbz_A 0 0 4 0 7 0 0 6 0 64 5 0 0 0 0 2 3 7 0 0 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 562 S b 3.9 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 5 4 4 6 1 5 2 1 3 0 2 3 1 4 11 40 5 3 0 0 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 563 Y S e 48.7 4qbz_A 4 1 2 9 5 6 11 5 3 7 1 7 0 2 6 7 5 1 3 12 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 564 N b 0.0 4qbz_A 3 0 2 2 0 0 2 4 0 2 0 70 0 4 3 4 2 0 0 0 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 565 S H e 21.1 4qbz_A 6 1 5 4 1 4 2 4 9 12 1 12 1 8 4 17 4 2 0 1 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 566 H H e 22.0 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[733 aa] 4 1 3 6 9 3 10 6 4 19 1 3 3 6 2 6 4 4 2 2 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 567 Y H e 25.7 4qbz_A CU8:7VF:7VC:DY3:O0W:QLH:GD0:I5N:I5B:RQY:JRI TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[736 aa] 4 4 3 5 8 4 2 5 4 8 2 5 4 3 6 12 8 5 2 6 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 568 F H b 1.4 4qbz_A QLH TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[736 aa]:Toll-like receptor 8[749 aa] 4 1 2 4 19 14 2 5 3 12 2 5 2 2 5 6 4 4 1 3 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 569 R T e 50.2 4qbz_A 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet.. TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[734 aa] 4 0 3 5 1 3 1 4 14 10 2 4 3 7 19 8 4 4 0 2 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 570 I e 40.9 4qbz_A UPT TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[736 aa] 4 1 2 2 2 3 1 23 2 26 3 5 5 1 2 5 2 9 0 1 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 571 A T e 53.6 4qbz_A UPT TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa]:Toll-like receptor 8[736 aa] 10 3 2 6 2 5 2 2 7 7 2 3 17 4 3 13 5 4 0 1 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 572 G T e 91.7 4qbz_A C09:L07:RX8:D80:XG1:URI:UPT:HB2:M8D:M0A:M4D:IDQ:MBL:U57 TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa] 10 3 2 8 2 31 2 2 6 2 1 4 4 3 5 8 3 3 0 1 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" G->D:LP/P:rs1385657: Immunodeficiency 98 with autoinflammation, X-linked (IMD98) ;G->V:LP/P:-: Immunodeficiency 98 with autoinflammation, X-linked (IMD98) ; 573 V S e 32.7 4qbz_A C09:L07:RX8:D80:XG1:URI:HB2:M8D:M0A:M4D:IDQ:U57 TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa]:Toll-like receptor 8[744 aa] 6 8 2 2 3 4 1 11 3 18 3 4 3 3 1 6 5 13 1 2 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 574 T e 38.3 4qbz_A C09:L07:RX8:D80:XG1:URI:HB2:M8D:M0A:M4D:IDQ:MBL:U57 TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[739 aa]:Toll-like receptor 8[734 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] SO4 4 5 3 5 5 4 1 9 5 11 2 2 11 2 3 5 16 6 0 2 MUTAGEN:/note="T->A: Abolishes responses to both ssRNA and chemical ligands.":MUTAGEN:/note="T->A: Strongly decreases activation of NF-kappa-B.":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":MUTAGEN:/note="T->A: Abolishes responses to both ssRNA and chemical ligands.":MUTAGEN:/note="T->A: Strongly decreases activation of NF-kappa-B.":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 575 H b 3.1 4qbz_A 5 2 7 9 2 6 13 4 6 4 1 6 4 3 8 9 3 4 1 2 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 576 H b 17.8 4qbz_A 5 3 5 4 4 6 17 3 6 8 2 8 5 5 4 6 3 3 0 2 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 577 L b 3.9 4qbz_A BU3 4 4 3 2 3 3 1 8 3 31 6 2 7 2 3 6 3 6 4 1 REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 16":TOPO_DOM:/note="Extracellular" 578 E G b 12.1 4qbz_A NAG 6 0 10 24 1 4 1 2 7 6 0 3 8 8 4 7 5 2 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 579 F G b 0.0 4qbz_A 7 5 3 6 22 4 1 4 2 10 2 2 2 3 2 8 3 6 1 5 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 580 I G b 1.2 4qbz_A 3 1 2 1 14 2 0 12 1 26 2 2 11 4 1 3 4 8 1 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 581 Q G e 44.9 4qbz_A NAG 7 3 5 7 0 11 2 3 9 3 3 3 5 14 7 8 4 3 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 582 N G e 53.9 4qbz_A NAG 7 2 3 8 3 13 4 1 7 3 1 15 5 6 4 8 6 2 0 2 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":TOPO_DOM:/note="Extracellular" 583 F b 3.3 4qbz_A 2 4 4 1 14 2 3 3 3 35 10 1 3 3 1 3 2 2 1 4 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 584 T S e 73.4 4qbz_A NAG TLR8_HUMAN:Toll-like receptor 8[747 aa] 5 2 3 4 1 5 2 3 10 2 2 4 12 4 5 14 16 4 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 585 N S e 39.4 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] 4 2 2 5 1 6 3 1 12 2 1 30 2 4 4 15 5 1 0 0 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 586 L b 0.0 4qbz_A 1 0 1 1 3 1 1 4 3 61 7 0 3 0 1 1 5 7 0 0 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 587 K e 47.6 4qbz_A NAG 3 0 3 10 2 2 2 2 16 5 0 4 3 12 15 10 5 4 0 2 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 588 V E e 26.0 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 4 2 2 7 2 2 3 11 6 8 2 3 0 7 6 6 7 14 2 7 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 589 L E b 0.6 4qbz_A 2 3 0 3 2 1 0 5 0 66 3 3 0 3 2 1 2 5 0 0 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 590 N E b 19.4 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 1 1 18 3 2 1 4 2 8 4 2 22 0 3 3 7 6 4 2 6 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 591 L b 0.6 4qbz_A 2 4 0 0 5 0 0 8 4 58 5 0 0 0 4 0 3 5 0 0 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 592 S T b 6.2 4qbz_A alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 12 0 5 2 2 3 3 2 2 9 0 5 1 8 4 30 6 0 0 5 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 593 H T e 30.9 4qbz_A 2 1 9 7 3 9 28 0 3 3 2 9 2 4 5 5 1 0 1 5 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 594 N S b 0.0 4qbz_A 3 1 7 8 0 0 0 4 0 1 0 62 4 0 0 5 3 0 0 0 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 595 N e 25.5 4qbz_A 3 2 4 6 2 7 4 2 8 3 0 30 2 9 7 6 4 0 0 1 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 596 I b 0.6 4qbz_A 2 1 0 4 5 1 0 26 1 29 2 0 2 1 2 3 4 9 2 4 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 597 Y e 23.5 4qbz_A TLR8_HUMAN:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[748 aa] 5 2 2 4 7 3 6 4 5 5 1 2 2 6 8 15 14 4 1 6 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 598 T b 19.5 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[681 aa] 3 1 5 8 3 14 2 3 3 4 3 4 1 3 5 13 20 3 0 2 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 599 L b 3.9 4qbz_A 2 1 3 3 6 4 1 21 4 28 3 2 3 2 2 3 1 10 0 2 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 600 T S b 17.5 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 4 1 4 4 3 5 2 9 3 5 1 3 16 4 3 10 14 6 1 1 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 601 D S e 78.4 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 4 0 10 13 3 5 2 4 4 3 2 5 17 3 4 10 4 2 0 2 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 602 K e 21.7 4qbz_A 7 3 5 6 4 12 2 4 9 7 2 5 7 5 5 6 4 4 0 3 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 603 Y e 28.3 4qbz_A 13 5 3 5 7 3 3 6 4 7 1 5 3 3 3 9 4 7 5 4 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 604 N e 27.9 4qbz_A 3 0 4 5 19 7 3 4 3 11 2 11 3 5 2 6 5 3 0 2 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 605 L b 2.2 4qbz_A BU3 5 5 3 3 5 7 1 6 4 27 2 3 3 3 4 6 3 3 2 2 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 606 E e 33.7 4qbz_A 4 1 4 13 1 12 4 1 6 7 1 8 6 9 6 11 2 2 0 2 REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 17":TOPO_DOM:/note="Extracellular" 607 S B b 3.1 4qbz_A 4 4 2 2 3 5 2 5 3 26 3 3 5 2 2 14 7 3 2 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 608 K S e 86.8 4qbz_A NAG 6 2 1 8 1 5 2 2 10 12 3 4 11 3 11 8 7 4 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 609 S S b 16.4 4qbz_A NAG 4 1 5 7 1 4 2 4 7 4 1 10 4 5 2 29 7 2 1 1 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 610 L b 0.0 4qbz_A 0 1 0 2 2 0 2 8 2 55 6 0 2 2 2 2 2 9 0 2 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 611 V e 34.7 4qbz_A NAG 4 1 2 10 3 3 1 7 4 12 1 1 5 10 8 4 8 14 1 2 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 612 E E e 25.6 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 5 1 6 26 3 3 3 3 5 3 2 4 2 7 4 10 7 4 1 3 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 613 L E b 0.0 4qbz_A BU3 3 0 0 3 3 2 1 6 2 59 2 5 0 0 2 3 2 4 0 2 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 614 V E b 9.3 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-a..:alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 5 3 10 3 3 4 4 6 4 13 2 4 4 3 4 5 7 13 2 3 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 615 F b 1.0 4qbz_A BU3 5 1 0 3 17 2 3 4 0 34 4 3 2 0 2 2 4 8 1 4 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 616 S T b 7.0 4qbz_A 5 2 5 8 2 4 3 3 2 2 0 11 2 6 5 34 3 2 0 2 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 617 G T b 19.0 4qbz_A 2 3 7 4 2 28 6 3 2 6 3 7 4 4 4 9 2 1 1 2 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 618 N S b 0.6 4qbz_A 1 2 6 4 2 6 3 3 2 5 1 45 0 2 3 5 5 2 0 0 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 619 R b 18.2 4qbz_A 4 3 2 3 2 3 5 3 12 3 1 7 5 8 18 9 2 6 0 2 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 620 L H b 0.0 4qbz_A 0 3 0 0 4 0 2 13 2 47 5 0 3 4 2 4 3 6 0 0 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 621 D H e 27.2 4qbz_A 3 0 14 10 0 4 4 3 6 3 3 6 4 7 4 15 9 3 2 0 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 622 I H e 35.1 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 5 2 2 5 5 6 3 12 4 12 6 2 3 3 3 9 4 13 0 2 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 623 L H b 0.6 4qbz_A 8 3 2 1 4 3 2 11 1 27 5 2 2 3 3 5 4 10 2 2 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 624 W T b 3.2 4qbz_A 3 1 2 3 8 9 3 4 5 6 1 4 9 2 5 7 3 4 13 6 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 625 N e 44.8 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[681 aa] 6 1 5 6 2 7 2 3 4 8 2 23 8 3 4 7 4 3 0 1 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 626 D T e 60.5 4qbz_A TLR8_HUMAN:Toll-like receptor 8[743 aa] 5 3 16 10 4 8 2 2 3 7 1 8 6 5 4 6 3 3 0 3 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 627 D T e 92.6 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 5 1 14 7 4 9 2 7 3 10 1 6 3 3 3 9 6 4 0 2 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 628 D e 21.0 4qbz_A TLR8_HUMAN:Toll-like receptor 8[743 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[730 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 4 1 15 10 3 5 2 4 5 6 1 7 4 5 4 8 5 3 3 2 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 629 N e 73.3 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 4 1 4 6 2 12 2 3 3 11 1 20 4 5 3 10 4 4 1 1 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 630 R T e 45.8 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[724 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[750 aa]:Toll-like receptor 8[708 aa]:Toll-like receptor 8[681 aa] 5 1 3 8 4 5 1 6 8 9 1 3 4 4 18 9 3 5 0 2 REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 18":TOPO_DOM:/note="Extracellular" 631 Y T b 0.0 4qbz_A 5 2 3 5 8 5 4 7 6 11 2 2 8 5 5 3 6 5 1 8 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 632 I T b 14.6 4qbz_A 4 3 4 2 5 8 3 9 3 11 1 5 15 2 6 5 4 8 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 633 S T e 25.0 4qbz_A 7 1 6 6 1 15 2 1 8 4 0 6 4 3 5 22 4 3 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 634 I T b 1.2 4qbz_A BU3 19 4 2 2 5 3 1 19 1 9 3 2 2 2 1 9 6 10 1 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 635 F T b 0.5 4qbz_A BU3 1 2 0 0 45 2 0 4 1 18 2 2 6 1 0 4 1 5 3 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 636 K T e 44.8 4qbz_A 7 1 4 6 1 5 2 3 14 7 1 3 4 9 12 14 3 2 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 637 G T e 20.2 4qbz_A 4 4 8 4 2 36 3 2 2 2 0 10 3 3 2 6 5 2 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 638 L B b 1.1 4qbz_A 3 5 2 1 3 0 0 3 0 56 9 4 2 1 1 1 1 5 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 639 K T e 64.6 4qbz_A NAG 4 0 2 5 2 3 4 2 20 3 1 4 9 7 11 9 6 6 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 640 N T e 47.9 4qbz_A NAG TLR8_HUMAN:Toll-like receptor 8[747 aa] 7 1 2 5 3 6 3 0 5 1 1 35 1 5 4 15 2 1 0 2 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 641 L b 0.0 4qbz_A 2 2 0 2 3 0 1 6 0 70 2 0 0 0 0 3 1 4 0 1 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 642 T e 27.3 4qbz_A NAG 4 2 1 14 1 4 3 4 6 3 2 4 4 9 8 8 16 5 1 1 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 643 R E e 22.1 4qbz_A beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-bet..:alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose..:alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-..:alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-.. 5 3 3 6 2 2 4 6 6 6 2 3 2 4 10 10 9 7 2 8 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 644 L E b 0.0 4qbz_A 0 0 0 2 7 0 0 11 0 64 3 0 3 3 0 2 2 3 0 0 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 645 D E b 13.0 4qbz_A 4 0 34 3 2 5 5 5 4 2 1 10 2 1 5 6 3 3 2 3 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 646 L b 0.0 4qbz_A 2 4 0 2 4 0 0 12 0 54 6 0 2 0 2 2 0 9 0 0 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 647 S b 6.2 4qbz_A 13 1 4 4 1 6 3 0 1 1 0 5 0 4 6 43 4 1 0 1 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 648 L S e 47.2 4qbz_A 4 1 6 3 6 10 8 4 6 9 3 8 0 3 8 8 3 2 1 7 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 649 N S b 0.0 4qbz_A 1 4 2 1 0 3 1 0 2 2 1 63 1 5 3 2 5 1 0 0 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 650 R e 49.4 4qbz_A 5 1 5 3 2 3 5 1 12 5 1 11 2 10 16 9 4 3 0 2 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 651 L b 0.6 4qbz_A 2 0 0 3 14 0 0 15 0 47 3 0 2 2 2 0 3 6 0 0 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 652 K S e 62.3 4qbz_A TLR8_HUMAN:Toll-like receptor 8[738 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[731 aa]:Toll-like receptor 8[727 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[746 aa] 6 0 3 8 1 6 4 1 6 3 0 4 2 7 14 15 12 4 0 2 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 653 H e 40.3 4qbz_A TLR8_HUMAN:Toll-like receptor 8[738 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[735 aa]:Toll-like receptor 8[743 aa]:Toll-like receptor 8[749 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[727 aa] 5 2 3 5 3 12 10 2 5 2 1 8 1 5 7 13 5 5 1 5 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 654 I b 7.0 4qbz_A 6 5 6 6 5 6 5 6 6 6 5 5 6 5 0 6 6 6 0 5 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 655 P e 20.2 4qbz_A 6 0 6 6 6 6 6 6 6 6 0 6 6 6 6 6 6 6 0 6 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 656 N H e 47.3 4qbz_A NAG 7 1 8 8 1 5 3 2 4 4 1 10 16 6 4 10 5 3 0 2 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 657 E H e 59.3 4qbz_A 6 1 10 18 2 12 1 2 5 5 2 4 5 4 6 7 4 2 1 1 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 658 A H b 0.9 4qbz_A 24 4 2 3 2 10 1 7 3 4 2 3 2 2 3 12 5 6 2 2 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 659 F H b 2.9 4qbz_A 2 3 1 1 35 2 2 4 1 18 3 4 2 1 2 4 3 7 1 2 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 660 L H e 38.8 4qbz_A NAG 7 5 5 4 4 6 2 7 3 21 1 3 3 4 7 5 3 5 1 3 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 661 N T b 10.9 4qbz_A 5 0 8 6 1 22 4 0 4 2 2 14 4 5 2 10 5 2 1 2 REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 19":TOPO_DOM:/note="Extracellular" 662 L S b 4.5 4qbz_A 2 2 2 2 4 2 0 3 3 47 3 4 2 0 3 3 3 6 6 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 663 P b 6.2 4qbz_A 5 4 4 5 1 4 4 3 3 7 3 4 31 3 4 6 4 3 0 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 664 A T e 53.6 4qbz_A 7 3 3 4 5 9 3 3 8 4 4 4 4 5 6 12 5 4 3 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 665 S T e 25.0 4qbz_A 6 5 6 6 5 6 5 6 6 6 0 5 0 5 6 6 6 6 5 5 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 666 L b 0.6 4qbz_A 0 0 4 4 6 0 0 8 0 49 8 0 5 0 0 4 5 6 0 0 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 667 T S e 24.0 4qbz_A 4 2 4 10 2 3 3 7 8 6 4 5 3 7 6 5 11 6 0 3 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 668 E E e 26.6 4qbz_A 3 1 2 24 4 3 4 2 5 12 1 4 0 10 3 4 9 4 1 6 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 669 L E b 1.7 4qbz_A 0 4 0 0 4 0 0 5 4 65 2 2 2 0 5 0 1 3 0 2 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 670 H E b 9.4 4qbz_A 2 1 12 3 6 4 18 2 6 7 0 13 0 3 5 7 3 1 1 8 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 671 I b 0.0 4qbz_A 2 4 0 2 4 2 0 10 0 50 8 1 0 2 0 4 0 8 0 0 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 672 N b 10.3 4qbz_A 5 0 11 5 1 6 4 3 3 5 2 16 1 4 5 20 3 3 0 4 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 673 D S e 48.8 4qbz_A 3 0 7 4 3 5 7 3 5 6 0 11 3 3 10 14 3 3 3 7 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 674 N S b 7.3 4qbz_A 8 7 8 0 0 8 0 8 8 8 0 7 8 0 8 8 8 8 0 0 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 675 M e 29.5 4qbz_A 3 2 2 5 3 6 4 4 8 9 8 7 3 8 10 8 2 4 1 2 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 676 L b 0.0 4qbz_A 2 3 0 0 5 0 2 22 2 42 2 2 2 0 1 2 5 6 0 0 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 677 K e 55.7 4qbz_A TLR8_HUMAN:Toll-like receptor 8[738 aa]:Toll-like receptor 8[737 aa]:Toll-like receptor 8[752 aa]:Toll-like receptor 8[742 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[681 aa] SO4 4 0 5 10 1 5 3 1 7 4 2 7 3 9 12 12 11 3 0 1 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 678 F e 49.8 4qbz_A NAG TLR8_HUMAN:Toll-like receptor 8[754 aa] 6 2 3 3 11 9 2 6 5 13 1 3 2 8 5 8 4 5 1 3 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 679 F b 6.7 4qbz_A 4 0 2 2 11 2 4 15 3 21 2 2 5 2 2 5 4 10 2 3 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 680 N e 22.4 4qbz_A NAG 6 2 12 4 1 5 5 4 5 3 0 14 15 2 2 11 4 3 0 2 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 681 W G b 2.4 4qbz_A 6 0 5 8 6 5 3 5 7 5 2 3 10 2 5 7 2 2 12 3 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 682 T G e 37.0 4qbz_A NAG 10 2 8 9 2 9 2 4 4 5 1 5 8 3 7 9 9 3 1 1 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 683 L G b 10.7 4qbz_A NAG 12 2 3 5 4 4 1 6 2 19 5 4 2 2 3 11 4 7 1 3 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 684 L G b 1.1 4qbz_A 4 3 2 4 20 3 3 7 2 33 2 0 4 0 0 2 4 4 0 2 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 685 Q G e 52.0 4qbz_A GOL 5 0 5 8 3 11 8 3 4 5 2 4 3 14 4 8 7 3 2 2 REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 20":TOPO_DOM:/note="Extracellular" 686 Q G e 54.1 4qbz_A 5 4 6 4 3 11 7 2 4 6 3 6 6 9 7 7 4 3 3 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 687 F b 2.4 4qbz_A 3 4 0 4 16 1 3 7 2 28 9 2 4 2 0 2 2 4 2 6 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 688 P T e 70.5 4qbz_A 4 0 3 5 1 8 2 2 7 3 1 4 34 2 4 12 6 3 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 689 R T e 67.2 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] 5 4 2 7 1 4 4 0 14 4 1 15 2 7 10 13 3 2 0 2 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 690 L b 1.1 4qbz_A 2 0 0 0 1 2 0 5 0 74 3 0 3 0 2 0 0 5 0 0 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 691 E e 36.2 4qbz_A 4 0 5 23 1 1 4 1 8 2 2 3 1 12 11 7 11 2 0 1 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 692 L E e 21.9 4qbz_A 3 0 2 9 4 3 2 10 3 18 3 1 1 2 6 6 6 12 2 5 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 693 L E b 0.0 4qbz_A 0 0 0 0 1 2 0 7 4 69 3 0 0 1 0 4 1 5 0 0 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 694 D E b 0.0 4qbz_A 2 1 39 5 2 5 4 2 2 1 1 9 0 4 4 7 5 2 2 4 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 695 L b 0.0 4qbz_A 2 2 0 0 4 1 0 5 0 69 4 0 0 0 0 0 2 7 0 2 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 696 R e 36.0 4qbz_A 4 1 6 6 1 8 3 0 3 1 1 8 2 5 11 32 4 2 0 2 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 697 G S e 21.4 4qbz_A 3 1 2 2 3 33 10 0 3 4 0 14 1 2 6 10 2 0 1 4 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 698 N S b 5.5 4qbz_A 2 2 0 0 0 1 2 0 2 4 1 69 1 1 0 6 5 1 0 1 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 699 K e 31.1 4qbz_A SO4 4 0 3 8 1 5 2 0 15 5 1 13 3 13 11 11 3 2 1 1 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 700 L b 1.7 4qbz_A 1 0 1 2 5 2 2 21 1 54 0 2 1 2 1 1 1 2 0 1 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 701 L e 55.6 4qbz_A TLR8_HUMAN:Toll-like receptor 8[751 aa] 5 1 3 7 2 3 3 6 6 10 2 2 2 3 7 13 16 4 1 2 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 702 F e 66.0 4qbz_A 5 1 3 4 8 11 5 6 3 7 2 2 1 5 4 14 7 4 1 6 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 703 L b 3.9 4qbz_A 2 1 2 5 1 1 0 17 1 38 1 1 3 2 2 4 3 13 0 1 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 704 T b 5.8 4qbz_A 6 0 6 6 2 6 1 9 2 6 1 3 23 2 5 11 7 2 0 1 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 705 D S e 61.7 4qbz_A 2 1 12 11 1 7 1 4 3 4 1 11 21 2 3 5 3 4 1 1 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 706 S e 23.4 4qbz_A 6 1 12 8 1 16 1 1 4 3 1 7 5 3 3 18 9 1 0 1 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 707 L G b 2.2 4qbz_A 11 1 1 2 5 3 2 13 2 27 3 1 4 1 1 10 6 5 1 0 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 708 S G e 30.5 4qbz_A GOL 5 4 2 1 23 5 1 5 1 11 1 4 6 3 2 15 6 4 0 3 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 709 D G e 64.8 4qbz_A GOL 7 2 12 6 1 10 5 2 6 5 0 8 3 7 7 13 2 2 2 0 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 710 F T b 11.0 4qbz_A GOL 4 1 3 1 20 10 3 4 3 15 4 8 4 2 1 9 4 2 1 1 REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 21":TOPO_DOM:/note="Extracellular" 711 T b 7.8 4qbz_A GOL 3 5 1 2 3 4 0 5 2 31 4 3 4 2 1 6 14 8 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 712 S S e 84.4 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] GOL 7 2 1 4 3 7 3 1 9 2 0 7 11 5 3 21 10 3 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 713 S b 14.8 4qbz_A 6 1 3 3 1 5 5 1 7 2 3 16 0 7 5 25 4 2 1 2 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 714 L b 0.0 4qbz_A 5 0 3 3 3 1 3 7 0 54 3 0 0 0 4 0 0 11 0 0 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 715 R e 48.2 4qbz_A SO4 3 0 6 5 4 3 3 5 14 8 4 2 2 7 17 4 5 3 0 3 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" R->Q:LB/B:rs5744082: -; 716 T E b 18.8 4qbz_A 5 2 4 7 5 2 3 4 4 8 2 5 0 2 4 13 14 8 5 3 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 717 L E b 0.0 4qbz_A 1 0 1 1 10 1 0 11 11 11 10 10 1 0 1 1 1 11 10 10 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 718 L E b 11.2 4qbz_A 1 2 19 3 4 2 3 8 2 12 2 11 2 3 2 5 3 4 3 8 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 719 L b 0.0 4qbz_A 3 2 0 0 3 0 2 7 0 61 5 0 0 2 2 3 1 7 0 0 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 720 S b 7.8 4qbz_A 6 1 10 4 1 11 2 0 2 0 2 6 2 6 2 38 4 0 0 1 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 721 H S e 61.8 4qbz_A 1 1 4 3 5 9 18 4 2 3 3 20 0 3 7 8 0 0 1 7 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 722 N S b 4.8 4qbz_A 4 1 0 0 0 0 0 1 2 2 0 73 4 2 0 6 2 0 0 0 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 723 R e 39.5 4qbz_A SO4 5 0 2 2 3 5 4 0 13 7 1 10 2 15 18 8 1 1 0 2 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 724 I b 0.0 4qbz_A 0 0 0 0 7 0 0 31 0 44 3 0 0 0 0 0 6 5 0 0 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 725 S e 43.8 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[748 aa] SO4 7 1 4 7 2 12 2 2 5 3 1 7 1 3 8 17 15 3 0 0 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 726 H e 60.2 4qbz_A SO4 4 2 4 7 3 14 9 2 4 2 1 4 2 6 5 12 7 6 1 4 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 727 L b 5.1 4qbz_A 3 0 1 2 4 1 0 21 2 41 2 2 1 1 0 2 2 14 0 1 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 728 P b 11.6 4qbz_A 6 0 3 7 1 1 3 6 0 3 0 3 48 2 1 6 3 5 0 0 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 729 S T e 55.5 4qbz_A 7 1 6 7 1 5 1 2 7 5 1 4 19 3 4 11 8 4 0 2 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 730 G T e 29.8 4qbz_A 7 1 7 6 5 25 4 2 4 3 0 7 2 2 4 13 6 1 0 1 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 731 F T b 1.9 4qbz_A 16 1 2 4 13 2 0 7 1 17 2 1 3 2 2 7 8 7 1 4 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 732 L T b 7.3 4qbz_A 2 2 1 2 35 4 1 7 1 28 2 0 2 1 1 2 3 3 1 3 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 733 S T e 23.4 4qbz_A 12 3 6 7 3 10 2 1 6 2 1 4 3 6 4 19 6 3 2 1 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 734 E T e 43.2 4qbz_A 3 3 12 9 3 9 4 1 8 4 0 12 8 6 4 6 4 2 0 2 REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 22":TOPO_DOM:/note="Extracellular" 735 V b 0.7 4qbz_A 7 3 0 1 4 2 1 4 2 47 5 1 2 2 0 2 4 11 4 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 736 S T e 45.3 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] 5 0 1 5 1 3 2 2 9 3 0 6 16 6 6 18 11 5 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 737 S T b 16.4 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] 6 0 2 5 3 5 7 1 9 2 1 14 2 7 8 20 5 3 0 1 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 738 L b 0.6 4qbz_A 1 0 0 0 1 0 0 8 0 79 3 0 0 0 0 0 1 2 1 0 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 739 K e 35.8 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] SO4 4 0 2 18 2 1 1 1 11 3 1 1 1 14 17 6 10 5 0 3 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 740 H E e 20.4 4qbz_A 4 0 1 11 4 0 11 7 6 4 1 2 0 1 7 10 6 16 2 7 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 741 L E b 2.8 4qbz_A 0 0 0 0 3 1 0 8 0 75 2 1 0 0 0 0 0 6 0 0 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 742 D E b 4.3 4qbz_A 2 0 39 2 2 2 5 1 3 1 2 15 1 2 3 7 2 4 1 6 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 743 L b 0.0 4qbz_A 2 1 0 0 4 0 0 11 0 62 5 0 0 0 0 1 2 7 0 2 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 744 S T b 1.6 4qbz_A 5 0 5 5 1 3 5 0 2 1 0 3 0 5 9 47 4 1 1 1 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 745 S T e 22.7 4qbz_A 4 0 8 4 3 14 11 0 4 3 1 16 1 1 7 17 1 0 1 4 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 746 N S b 1.8 4qbz_A 2 0 0 0 1 2 2 0 1 2 0 83 0 0 0 1 2 0 0 1 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 747 L e 48.3 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[748 aa] 9 1 2 4 3 3 5 5 10 12 3 8 3 8 11 7 2 1 1 1 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 748 L b 0.0 4qbz_A 3 1 1 1 5 1 0 26 1 52 1 1 1 1 1 1 1 3 0 0 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 749 K S e 48.6 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[740 aa]:Toll-like receptor 8[748 aa] SO4 4 0 1 9 2 2 2 1 14 4 4 7 1 11 11 12 12 3 0 1 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 750 T e 24.7 4qbz_A SO4 9 1 4 5 3 6 3 2 5 3 3 7 1 3 1 17 19 6 0 1 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 751 I b 1.2 4qbz_A 1 1 1 1 8 1 0 23 1 35 1 1 4 1 1 4 2 12 0 0 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 752 N e 50.9 4qbz_A SO4 4 0 8 6 1 7 4 4 4 2 1 9 24 4 2 15 2 1 0 1 CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":CARBOHYD:/note="N-linked (GlcNAc...) asparagine":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 753 K H e 52.4 4qbz_A 5 0 1 10 2 6 2 2 16 6 1 3 19 8 5 6 1 3 1 4 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 754 S H e 31.2 4qbz_A 5 0 8 10 2 12 1 3 3 3 0 6 5 4 4 24 7 2 1 0 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 755 A H b 0.9 4qbz_A 20 3 2 4 2 5 1 8 1 8 2 1 6 7 2 8 6 9 2 1 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 756 L H b 3.4 4qbz_A 3 1 2 2 30 2 1 8 1 33 2 1 3 2 1 1 2 5 1 1 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 757 E e 46.2 4qbz_A 6 2 10 18 4 7 4 2 3 3 1 5 6 12 5 6 2 2 1 1 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 758 T b 18.8 4qbz_A 5 1 3 6 5 7 2 3 5 12 1 6 7 3 3 17 8 4 1 1 REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular":REPEAT:/note="LRR 23":TOPO_DOM:/note="Extracellular" 759 K S e 77.4 4qbz_A 5 1 4 4 3 9 4 2 7 18 1 6 6 7 4 6 3 4 4 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 760 T S e 60.4 4qbz_A 6 0 4 3 4 7 4 3 4 7 2 6 11 5 4 13 12 4 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 761 T e 74.0 4qbz_A NAG 4 4 2 3 8 6 1 2 3 22 4 2 7 4 2 13 5 5 1 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 762 T b 16.2 4qbz_A NAG 5 0 3 3 2 8 1 1 6 9 1 4 10 8 7 12 12 6 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 763 K e 60.4 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] SO4 6 0 3 4 1 4 3 2 18 3 0 19 2 8 8 9 2 3 1 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 764 L b 5.6 4qbz_A NAG 1 1 0 0 1 0 1 9 1 68 2 1 1 1 1 1 0 7 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 765 S e 28.1 4qbz_A NAG 6 1 3 13 1 2 1 3 11 6 1 6 3 4 11 15 8 5 0 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 766 M E e 20.8 4qbz_A 4 0 3 6 7 3 5 7 1 9 4 3 0 5 5 8 13 12 1 5 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 767 L E b 2.8 4qbz_A 1 1 0 0 3 0 0 13 1 65 0 3 0 0 1 1 1 9 1 1 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 768 E E b 14.1 4qbz_A 5 0 14 9 4 5 3 2 4 4 0 11 0 6 7 8 4 2 1 9 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 769 L b 0.0 4qbz_A 9 0 0 0 4 0 0 8 0 68 3 0 0 0 0 0 1 5 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 770 H T b 8.9 4qbz_A 4 1 9 5 2 13 12 0 0 1 1 7 0 5 8 17 9 1 0 5 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 771 G T e 54.8 4qbz_A 4 0 11 2 2 41 5 0 3 0 0 10 0 4 3 9 1 0 0 2 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 772 N b 3.6 4qbz_A 0 0 1 1 1 0 0 1 0 0 0 93 1 0 0 3 1 0 0 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 773 P e 36.4 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[746 aa]:Toll-like receptor 8[750 aa] 3 0 4 1 0 1 2 2 4 4 1 6 60 3 2 5 2 1 0 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 774 F E b 0.0 4qbz_A 0 0 0 0 29 1 0 8 0 24 0 1 2 0 0 0 1 1 32 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 775 E E e 38.7 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[750 aa] 11 0 10 12 2 0 8 6 4 7 1 7 0 7 5 2 7 5 0 4 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 776 C b 3.3 4qbz_A 2 88 0 0 0 5 0 2 1 0 0 0 0 0 0 0 0 0 0 0 DISULFID::DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DISULFID::DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 777 T S e 29.2 4qbz_A 3 1 34 2 0 6 1 2 0 2 0 10 2 1 1 14 16 3 0 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 778 C G e 84.7 4qbz_A 1 84 0 1 0 1 1 1 0 2 0 0 2 1 2 2 0 0 0 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 779 D G e 64.8 4qbz_A 2 0 13 25 0 8 7 0 3 0 0 6 6 5 11 8 1 3 0 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 780 I G b 2.9 4qbz_A 5 0 0 1 7 2 5 16 0 45 6 4 1 1 0 1 1 4 0 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 781 G H e 21.4 4qbz_A 11 3 5 3 1 10 1 2 7 18 1 1 1 7 9 7 2 3 4 4 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 782 D H e 30.9 4qbz_A 4 0 12 4 1 6 4 2 2 2 0 6 7 4 2 13 3 2 21 5 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 783 F H b 0.0 4qbz_A 1 1 1 1 35 1 0 3 1 43 3 0 1 0 1 1 1 4 2 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 784 R H b 18.2 4qbz_A 4 2 1 4 3 2 3 4 7 15 1 2 4 3 18 8 6 12 1 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 785 R H e 51.4 4qbz_A 5 0 9 4 1 2 6 0 5 2 0 6 3 15 21 8 7 1 2 2 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 786 W H b 8.4 4qbz_A 2 0 0 2 4 3 1 2 1 10 1 1 0 1 2 1 1 2 63 2 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 787 M H b 0.5 4qbz_A 7 0 2 1 1 3 0 11 1 37 6 0 2 5 1 2 3 13 2 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 788 D H e 46.3 4qbz_A 6 0 11 9 0 3 0 1 16 5 1 10 2 11 10 7 4 2 0 2 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 789 E H e 69.8 4qbz_A TLR8_HUMAN:Toll-like receptor 8[747 aa] 10 0 9 21 1 5 3 1 3 9 0 6 1 9 7 9 4 2 0 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 790 H e 24.1 4qbz_A NAG 3 0 3 2 3 3 15 2 6 8 2 16 1 11 2 9 2 3 5 4 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 791 L T e 49.4 4qbz_A 7 0 2 3 7 3 1 4 4 23 2 2 6 2 4 5 12 10 0 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 792 N T e 67.9 4qbz_A NAG TLR8_HUMAN:Toll-like receptor 8[747 aa] 3 0 6 6 1 8 2 1 7 3 0 19 4 9 8 13 6 3 0 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 793 V S b 2.0 4qbz_A NAG 8 0 1 5 5 7 0 8 2 8 2 3 2 2 4 8 7 24 0 2 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 794 K B e 52.8 4qbz_A 2 1 2 5 4 7 3 2 16 13 3 4 2 6 9 5 5 8 0 3 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 795 I b 3.5 4qbz_A 4 0 1 1 6 5 0 16 1 19 4 1 1 3 2 5 2 23 1 3 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 796 P e 20.2 4qbz_A 5 1 7 7 2 8 1 3 3 3 2 3 33 4 2 6 1 4 0 4 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 797 R e 41.1 4qbz_A 5 0 7 9 3 11 1 3 5 4 1 4 2 2 21 8 2 1 6 3 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 798 L G b 4.5 4qbz_A 4 2 3 5 5 2 1 3 5 18 4 1 15 5 2 7 9 7 3 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 799 V G b 7.3 4qbz_A 10 2 9 14 0 7 0 1 2 9 1 3 7 5 3 6 5 14 0 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 800 D G e 22.2 4qbz_A 2 2 24 10 2 5 2 3 3 3 1 12 1 9 5 11 4 3 0 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 801 V S b 0.7 4qbz_A 11 0 1 1 0 4 2 13 1 18 5 0 3 0 2 4 8 15 0 10 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 802 I B e 22.2 4qbz_A 4 0 0 1 3 1 1 13 3 11 8 2 6 4 9 3 17 8 0 7 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 803 C E b 0.0 4qbz_A 2 90 0 3 0 0 0 0 0 1 0 0 0 0 0 4 0 0 0 0 DISULFID::DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DISULFID::DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 804 A E e 26.8 4qbz_A TLR8_HUMAN:Toll-like receptor 8[748 aa]:Toll-like receptor 8[750 aa] 34 0 10 6 1 8 3 3 1 1 3 2 1 6 3 7 4 6 0 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 805 S E e 29.7 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[750 aa] 10 0 2 5 3 11 5 3 1 2 1 5 1 3 0 29 12 1 1 7 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 806 P S e 35.7 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[748 aa] 2 0 0 1 0 0 0 0 0 3 0 1 86 0 1 2 1 0 0 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 807 G T e 82.1 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[750 aa] 9 0 3 17 2 17 1 1 6 5 2 2 15 3 3 8 1 3 0 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 808 D T e 75.3 4qbz_A 4 1 10 13 2 4 10 2 6 4 0 3 2 6 4 19 4 1 1 3 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 809 Q T b 9.7 4qbz_A 2 2 4 0 8 3 1 2 8 26 9 1 2 4 3 4 2 15 1 6 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 810 R T e 66.8 4qbz_A TLR8_HUMAN:Toll-like receptor 8[746 aa]:Toll-like receptor 8[747 aa]:Toll-like receptor 8[751 aa]:Toll-like receptor 8[754 aa]:Toll-like receptor 8[745 aa]:Toll-like receptor 8[748 aa]:Toll-like receptor 8[750 aa] 8 1 1 4 1 1 4 2 24 1 0 1 0 16 28 2 3 0 0 3 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 811 G T e 60.7 4qbz_A 2 0 3 2 0 71 4 1 0 2 0 2 2 1 2 3 1 0 2 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 812 K S e 38.2 4qbz_A 4 0 2 6 2 3 5 2 13 4 7 0 3 18 14 6 4 6 1 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 813 S B b 2.3 4qbz_A 9 1 7 3 2 2 1 0 2 11 0 6 13 4 7 25 4 3 0 2 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 814 I G b 0.0 4qbz_A 4 0 0 2 4 2 0 18 2 32 2 0 0 0 0 2 0 30 1 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 815 V G b 18.0 4qbz_A 9 0 3 1 10 2 3 4 7 25 3 0 3 4 9 6 2 6 1 2 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 816 S G e 36.7 4qbz_A 10 0 16 9 2 2 1 2 1 4 0 5 1 5 8 25 6 5 0 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 817 L b 8.4 4qbz_A 3 0 0 2 12 0 1 9 1 37 2 0 0 5 0 2 5 18 0 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 818 E e 92.0 4qbz_A 3 0 18 20 2 0 6 3 2 4 0 9 5 5 11 9 2 1 0 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 819 L e 108.4 4r09_B 3 1 2 3 4 0 0 7 1 42 5 7 6 4 1 4 5 3 2 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 820 T G e 78.6 5hdh_A 9 2 4 9 4 1 1 2 4 3 5 4 4 0 10 27 6 3 0 3 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 821 T G e 77.3 5hdh_A 2 1 10 11 0 4 2 2 5 8 1 6 6 3 1 9 19 10 0 1 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 822 C G e 32.7 5hdh_A 1 63 1 2 4 1 0 5 0 14 0 3 0 0 0 2 2 0 0 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 823 V e 120.7 5hdh_A 4 5 6 6 4 0 4 2 7 14 2 1 2 9 2 8 3 15 0 5 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 824 S S e 72.7 7crf_B 10 16 10 3 3 5 0 3 4 3 2 1 6 2 7 15 6 2 0 0 DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular":DOMAIN:/note="LRRCT":TOPO_DOM:/note="Extracellular" 825 D e 82.7 7crf_B 4 0 23 9 0 5 5 1 0 6 0 10 11 3 2 13 5 2 0 0 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 826 V e 50.7 7crf_B 10 0 0 3 3 3 0 7 5 16 5 2 3 4 3 5 8 18 2 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 827 T e 83.1 7crf_B 6 0 1 4 0 6 0 3 4 12 0 2 7 3 3 9 24 11 0 3 TOPO_DOM:/note="Extracellular":TOPO_DOM:/note="Extracellular" 828 A 22 0 0 4 3 3 1 5 6 11 3 2 5 5 0 11 6 11 0 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 829 V 11 2 0 3 2 2 1 13 3 12 5 2 2 0 1 10 8 17 3 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 830 I 6 6 6 6 6 6 6 6 0 6 0 6 6 6 0 6 6 6 6 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 831 L 8 13 0 0 9 7 0 10 0 15 4 0 4 5 0 6 0 11 0 4 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 832 F 8 6 1 1 21 8 0 8 6 5 0 1 4 1 1 8 7 4 3 9 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 833 F 4 4 3 1 12 7 0 4 7 12 5 0 1 0 5 10 7 11 0 8 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 834 F 5 7 0 0 18 3 4 12 0 15 0 3 0 0 0 12 5 4 3 7 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 835 T 0 10 3 0 0 3 0 4 0 12 0 4 5 0 0 20 27 11 0 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 836 F 12 3 0 0 25 5 0 11 0 17 2 3 3 0 0 3 4 10 0 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 837 F 9 3 0 4 14 4 3 7 0 35 0 3 3 0 0 7 2 5 0 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 838 I 8 0 0 0 7 4 0 6 0 29 3 0 3 0 4 5 4 23 0 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 839 T 0 3 3 0 5 9 0 7 0 23 2 0 2 4 0 9 18 16 0 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 840 T 8 0 4 3 2 7 0 0 0 26 7 0 0 0 0 10 20 11 0 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 841 M 4 0 0 4 6 7 0 12 0 33 4 5 3 0 0 2 5 14 0 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 842 V 6 3 3 0 7 6 0 10 0 15 4 4 0 0 0 4 5 31 0 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 843 M 2 2 0 0 2 2 0 8 4 35 11 0 0 8 3 10 5 7 0 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 844 L 14 3 0 0 4 3 0 19 0 27 2 4 0 0 0 0 5 17 0 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 845 A 14 2 0 1 3 10 6 4 0 6 5 2 6 4 0 2 10 20 4 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 846 A 14 5 0 0 4 14 2 3 0 11 2 0 7 0 7 8 6 16 0 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 847 L 0 0 0 0 7 3 0 11 4 31 6 0 0 0 2 3 6 16 2 7 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 848 A 19 9 0 4 5 1 0 4 2 27 0 4 0 2 5 2 6 7 2 0 TRANSMEM:/note="Helical":TRANSMEM:/note="Helical" 849 H 2 4 0 8 5 0 33 6 0 4 0 0 3 2 0 11 0 13 0 8 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 850 H 9 2 0 4 0 8 33 0 4 9 0 7 0 1 4 4 3 0 0 9 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 851 L 4 8 0 0 15 0 0 2 9 34 3 0 0 3 11 0 0 8 0 2 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 852 F 1 7 0 6 25 3 6 3 2 12 0 3 3 0 5 2 0 4 6 12 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 853 Y 1 0 1 4 10 12 6 6 1 10 0 0 1 7 4 3 1 5 0 27 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 854 W 6 2 4 1 11 3 3 3 3 8 6 0 1 0 4 1 1 1 38 3 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 855 D 1 0 24 1 3 4 7 3 9 1 0 4 6 0 8 7 3 4 2 12 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 856 V 3 3 0 1 2 1 0 10 7 30 15 0 6 0 0 1 6 11 0 3 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 857 W 1 0 0 1 5 1 0 0 7 6 8 3 4 0 14 6 0 3 33 7 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 858 F 3 3 4 4 13 3 0 5 0 10 19 0 0 3 0 1 3 1 8 19 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 859 I 6 11 4 1 4 1 2 18 0 19 9 0 0 0 0 1 3 15 0 5 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 860 Y 3 3 0 0 17 1 3 0 3 1 3 0 0 0 11 1 4 8 22 19 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 861 N 13 0 4 8 3 6 10 4 4 6 8 16 1 3 7 1 1 1 0 3 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 862 V 8 4 1 9 5 1 0 5 1 19 7 1 1 1 3 1 6 15 11 1 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 863 C 7 34 4 5 1 6 1 1 1 17 0 1 1 3 1 6 2 1 4 2 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 864 L 1 0 1 4 4 1 0 4 7 30 0 0 4 21 8 2 1 6 2 6 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 865 A 41 1 10 0 0 2 5 4 12 1 0 0 0 8 3 0 3 0 8 0 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 866 K 9 4 0 0 0 7 5 0 23 7 3 0 0 0 14 3 10 3 5 6 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 867 V 0 5 6 0 0 6 0 10 11 19 4 1 6 7 11 0 2 9 0 2 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 868 K 4 2 0 4 5 0 0 0 32 5 0 2 7 6 20 4 7 1 0 0 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 869 G 0 0 0 0 3 42 0 0 20 1 0 3 12 3 11 0 0 0 4 0 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 870 Y 1 6 10 4 9 2 8 1 4 5 0 1 8 2 6 1 1 9 1 21 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 871 R 1 0 11 5 0 2 3 1 21 1 0 0 1 5 43 3 1 1 3 0 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 872 S 9 3 4 8 1 7 2 1 18 4 0 1 11 4 7 12 7 3 0 0 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 873 L 14 1 4 2 5 4 1 10 2 25 1 1 1 6 7 3 2 5 0 7 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 874 S 3 0 8 6 1 18 0 2 8 2 0 1 16 10 9 12 1 1 0 1 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 875 T 2 2 6 9 1 10 0 1 4 5 0 1 3 1 31 6 15 2 0 0 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 876 S 7 0 3 11 4 19 0 1 12 1 2 4 2 2 14 9 6 1 0 0 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 877 Q 6 0 20 26 0 0 0 0 5 8 4 1 3 11 6 2 4 0 0 0 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 878 T 2 2 3 5 10 0 0 11 6 10 0 8 4 9 0 13 5 5 0 6 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 879 F 2 18 4 6 19 1 0 8 1 19 3 3 1 2 5 1 6 2 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 880 Y 0 0 4 0 13 0 7 0 0 0 0 4 0 0 4 0 0 0 0 67 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 881 D 5 0 79 0 0 2 3 0 0 1 0 0 0 0 0 5 2 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 882 A 80 5 0 0 0 0 0 0 0 0 0 0 0 4 5 0 0 6 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 883 Y 0 0 0 5 64 0 0 0 0 0 0 0 0 0 0 0 0 4 5 22 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 884 I 0 0 5 0 7 0 0 26 0 6 0 0 0 0 0 0 0 57 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 885 S 4 6 0 0 0 0 0 19 0 3 0 0 0 0 0 53 0 12 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 886 Y 0 0 0 0 22 0 11 0 0 5 0 0 0 0 0 0 0 0 0 58 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 887 D 8 5 23 0 0 0 0 0 0 0 0 5 0 0 0 59 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 888 T 9 0 2 23 0 3 5 0 9 4 0 8 0 0 3 25 5 0 0 4 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 889 K 7 5 0 4 0 0 10 0 30 0 0 2 0 23 8 0 7 1 3 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 890 D 0 0 75 4 0 0 0 0 0 0 0 4 0 9 0 8 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 891 A 9 0 1 19 6 1 0 1 2 1 0 1 2 9 7 38 1 1 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 892 S 24 1 2 2 2 9 5 1 2 4 1 1 9 3 1 9 10 2 0 13 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 893 V 5 1 8 7 6 5 1 6 4 6 1 3 8 3 3 4 4 23 1 2 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 894 T 13 6 3 12 2 4 1 3 3 5 1 3 3 2 3 9 16 8 1 2 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 895 D 3 1 39 24 1 2 2 2 2 3 1 8 2 1 2 2 2 2 0 1 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 896 W 4 0 0 5 5 0 0 0 0 3 0 0 0 5 0 0 0 0 70 4 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 897 V 6 0 0 0 3 0 0 5 0 4 0 0 0 0 0 0 0 79 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 898 I 0 3 0 15 0 4 0 10 9 13 0 0 0 6 13 0 0 7 6 11 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 899 N 6 0 0 9 0 0 3 0 6 0 0 59 4 5 0 5 1 0 0 2 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 900 E 6 0 3 46 0 6 9 2 0 17 0 0 0 9 0 0 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 901 L 0 0 0 4 2 6 0 0 0 58 17 0 0 0 0 5 5 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 902 R 4 0 1 5 0 1 2 5 1 18 3 1 1 1 12 3 6 36 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 903 Y 10 6 0 5 5 2 0 0 21 1 0 0 19 15 1 2 1 8 0 3 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 904 H 6 0 0 11 0 1 19 0 4 1 2 22 4 13 4 8 1 3 0 1 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 905 L 6 0 0 2 0 0 0 0 0 76 4 0 4 0 0 2 0 3 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 906 E 5 0 6 70 0 0 0 0 0 4 6 0 0 6 0 0 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 907 E 3 0 3 45 0 3 8 0 12 5 0 6 0 9 0 0 3 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 908 S 6 1 5 3 10 24 4 1 3 2 4 7 7 1 9 8 1 1 0 4 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 909 R 5 3 1 18 3 9 1 1 1 6 1 1 1 3 20 10 1 13 0 1 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 910 D 1 0 29 10 5 15 0 0 0 1 0 11 21 2 3 1 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 911 K 0 0 0 8 0 7 7 5 7 4 0 3 32 12 12 0 2 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 912 N 1 0 7 6 1 15 4 1 5 2 0 8 13 1 16 11 8 1 1 1 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 913 V 10 0 0 0 35 0 0 8 0 25 1 0 0 0 3 0 0 10 0 9 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 914 L 0 0 0 0 3 0 2 0 24 22 0 4 0 17 28 0 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 915 L 0 0 0 0 8 0 0 10 0 76 0 0 0 0 0 0 0 6 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 916 C 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 917 L 0 0 0 0 9 0 0 0 0 87 0 0 0 0 0 0 0 4 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 918 E 0 0 0 30 0 0 52 0 0 5 0 0 7 4 0 0 0 0 0 2 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 919 E 3 0 6 48 0 0 4 0 14 0 0 3 0 5 0 0 0 0 0 16 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 920 R 0 0 0 0 0 2 0 0 0 0 0 0 0 0 96 2 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 921 D 0 0 89 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 2 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 922 W 0 0 0 0 63 0 0 0 0 4 0 0 0 0 0 2 0 10 20 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 923 D 4 0 7 13 0 3 0 25 0 16 0 5 3 0 0 0 5 17 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 924 P 9 0 0 0 0 0 4 9 0 0 0 0 70 0 0 0 0 7 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 925 G 0 0 4 0 0 90 0 0 0 0 0 5 0 0 0 0 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 926 L 6 0 0 6 3 13 0 2 37 3 0 4 0 5 0 0 0 19 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 927 A 17 0 12 0 2 0 4 0 0 6 0 6 5 0 0 11 10 5 14 9 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 928 I 0 0 0 4 0 2 3 51 2 13 2 0 0 0 6 0 4 7 0 5 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 929 I 19 0 0 0 12 0 4 22 0 12 3 0 7 0 0 2 8 11 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 930 D 14 0 30 46 0 0 0 0 0 0 0 0 0 0 0 3 0 3 0 4 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 931 N 13 0 7 0 0 0 0 0 0 0 0 69 0 4 0 3 3 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 932 L 0 0 0 0 0 0 0 65 0 26 3 0 0 0 0 0 2 3 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 933 M 0 0 0 0 0 0 0 43 0 4 7 0 0 8 0 4 3 22 10 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 934 Q 16 0 20 13 0 0 0 0 0 0 0 21 0 18 4 7 1 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 935 S 24 6 0 0 5 11 0 5 0 0 0 0 0 0 0 49 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 936 I 5 0 0 0 11 0 0 57 0 0 7 0 0 0 0 0 4 16 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 937 N 4 0 3 30 0 3 11 0 9 3 0 8 0 4 8 0 0 0 6 10 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 938 Q 0 0 4 0 0 5 0 0 44 4 0 6 0 3 8 19 2 4 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 939 S 5 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 940 K 0 0 0 0 0 0 11 0 12 0 0 0 0 0 66 0 0 0 0 11 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 941 K 3 0 0 0 0 0 0 0 71 0 0 0 0 5 17 0 3 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 942 T 1 0 0 0 5 5 0 11 0 0 2 0 0 0 0 10 50 15 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 943 V 0 0 0 0 0 0 0 55 0 19 2 0 0 0 0 0 0 23 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 944 F 0 18 0 0 54 0 0 8 0 5 3 0 0 0 0 0 0 11 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 945 V 0 0 0 0 0 0 0 5 0 10 0 0 0 0 0 0 0 85 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 946 L 0 0 0 0 0 0 0 9 0 63 4 0 0 0 0 0 0 24 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 947 T 7 0 2 0 0 0 0 0 0 0 0 0 0 0 0 68 22 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 948 K 0 0 2 17 0 3 13 0 8 0 0 2 16 21 15 3 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 949 K 3 0 0 0 0 0 28 0 6 0 0 41 0 3 0 8 10 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 950 Y 3 0 10 0 59 0 0 0 0 11 0 0 0 0 0 0 0 0 0 16 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 951 A 10 0 0 0 0 0 0 21 0 32 0 0 5 1 8 0 0 23 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 952 K 0 3 0 0 0 0 2 0 32 0 0 3 0 29 12 3 0 10 0 5 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 953 S 0 0 14 0 0 0 0 0 0 0 0 11 3 0 0 57 10 5 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 954 W 0 0 0 46 5 17 0 0 0 0 0 0 10 0 14 0 0 0 9 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 955 N 0 4 0 6 0 0 0 0 0 16 0 5 0 0 6 2 0 0 59 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 956 F 4 60 0 0 9 0 0 0 0 16 4 0 0 0 0 5 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 957 K 0 0 0 0 0 0 11 11 30 7 0 0 0 6 30 0 0 0 0 4 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 958 T 15 0 0 11 20 0 0 2 0 11 2 0 0 0 6 0 4 2 0 25 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 959 A 20 0 0 57 0 0 0 0 6 5 0 0 0 0 0 10 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 960 F 0 0 0 0 34 0 0 0 0 26 0 5 2 0 0 0 0 15 0 17 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 961 Y 0 0 14 11 0 1 9 4 9 10 0 6 0 3 12 4 0 0 0 18 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 962 L 4 0 0 0 25 4 6 11 0 30 0 0 0 0 2 9 0 0 0 7 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 963 A 78 0 0 0 0 0 0 0 0 0 0 0 0 0 4 18 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 964 L 0 0 0 0 0 0 37 0 0 9 5 0 0 29 0 3 5 9 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 965 Q 0 0 0 5 14 4 17 0 0 1 3 0 0 29 5 8 12 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 966 R 0 0 0 6 0 0 0 0 3 5 0 12 0 9 38 13 0 0 12 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 967 L 13 4 0 0 0 0 0 4 0 58 3 0 0 11 0 3 0 3 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 968 M 0 0 0 0 39 0 0 9 0 31 5 0 0 0 0 0 0 12 0 4 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 969 D 4 0 27 19 0 0 11 0 5 11 0 4 0 0 3 11 0 0 0 3 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 970 E 4 0 21 39 0 0 0 0 0 0 0 0 0 15 11 10 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 971 N 1 0 0 0 0 10 3 0 4 7 0 32 0 0 19 18 6 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 972 M 0 0 0 0 1 4 2 0 21 17 3 17 4 0 17 9 0 4 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 973 D 8 0 56 0 0 0 0 0 6 0 0 2 4 0 9 14 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 974 V 15 0 0 0 0 11 2 3 0 6 0 6 0 0 8 10 0 36 0 2 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 975 I 13 0 0 0 0 1 0 45 0 27 0 0 0 0 0 0 0 11 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 976 I 0 0 0 0 4 0 0 70 0 10 0 0 0 0 0 0 0 15 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 977 F 0 0 0 0 20 0 0 6 0 59 4 0 0 0 0 0 0 11 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 978 I 0 0 0 0 0 0 0 63 6 0 0 0 0 0 0 0 0 30 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 979 L 0 0 0 0 26 0 0 19 0 34 0 0 0 0 0 0 0 22 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 980 L 0 6 0 0 0 0 0 0 0 77 0 0 0 0 0 0 0 7 0 10 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 981 E 1 1 1 57 0 16 1 0 0 0 0 0 0 10 6 7 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 982 P 0 0 10 3 0 0 0 0 16 0 0 4 60 0 0 7 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 983 V 3 5 16 0 0 0 0 34 0 18 0 3 4 0 0 0 0 13 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 984 L 9 0 8 16 2 6 0 0 0 7 0 0 19 2 0 16 0 0 0 11 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 985 Q 0 0 4 6 2 0 4 0 34 2 0 0 0 30 8 7 0 0 0 4 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 986 H 0 0 0 0 0 0 6 0 19 11 0 2 0 2 15 19 3 4 0 18 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 987 S 14 0 6 8 0 0 0 0 1 7 0 13 0 8 11 27 4 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 988 Q 0 0 0 0 0 4 9 10 13 3 0 2 6 18 29 5 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 989 Y 9 0 9 0 18 0 4 0 0 8 0 0 4 11 0 0 0 0 0 38 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 990 L 0 14 0 4 4 0 16 0 0 22 9 0 6 4 0 0 0 22 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 991 R 0 9 9 18 0 0 0 0 23 0 0 0 0 4 23 8 0 6 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 992 L 0 0 0 0 0 0 0 7 6 77 5 0 0 0 0 0 0 4 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 993 R 4 0 0 0 4 0 0 0 19 0 0 0 0 0 61 0 0 0 0 11 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 994 Q 18 0 4 0 0 7 5 0 21 3 0 0 0 13 24 2 1 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 995 R 0 0 0 0 7 9 0 18 0 30 0 0 0 0 23 0 0 1 0 13 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 996 I 0 0 0 0 0 0 0 11 0 48 31 0 0 0 0 0 0 10 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 997 C 5 17 0 9 9 0 0 0 8 6 0 18 0 7 9 11 1 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 998 K 0 0 0 0 0 2 0 0 30 0 4 0 6 5 30 0 23 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 999 S 0 0 0 0 0 4 0 0 22 0 0 19 0 20 8 21 6 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1000 S 4 9 4 0 0 0 0 0 0 0 0 0 0 7 0 22 48 6 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1001 I 0 5 0 0 3 0 0 12 0 0 0 0 0 0 0 0 6 14 0 60 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1002 L 0 4 0 0 0 0 0 12 0 77 0 0 0 0 0 0 0 0 6 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1003 Q 0 0 0 49 3 0 0 0 10 12 0 9 0 8 7 0 3 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1004 W 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 89 4 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1005 P 0 0 5 11 0 8 0 0 0 6 0 0 69 0 0 0 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1006 D 2 0 35 11 0 0 9 0 15 2 0 6 2 1 0 0 8 9 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1007 N 0 0 24 18 0 0 0 0 9 0 0 10 0 19 0 17 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1008 P 5 0 0 12 0 1 0 0 22 8 0 0 19 0 5 1 9 18 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1009 K 2 0 1 20 1 4 9 1 4 13 0 3 1 18 7 13 3 1 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1010 A 14 0 8 1 1 27 1 1 12 1 0 1 1 15 14 1 1 1 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1011 E 1 4 5 11 1 1 8 5 5 1 0 1 1 20 16 7 1 12 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1012 G 1 0 0 6 0 35 12 5 1 1 0 8 11 3 5 11 1 1 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1013 L 12 0 1 1 0 7 0 15 1 22 2 1 1 1 7 10 1 4 11 4 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1014 F 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1015 W 0 0 0 0 0 0 6 0 0 7 0 0 0 0 2 0 0 0 84 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1016 Q 24 0 8 2 0 0 12 0 0 9 0 0 0 16 16 0 10 3 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1017 T 0 4 0 0 0 0 0 0 33 0 0 28 0 14 14 2 1 0 4 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1018 L 0 0 0 0 0 0 0 10 0 90 0 0 0 0 0 0 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1019 R 0 0 0 0 0 7 0 0 16 0 0 0 0 5 62 8 0 0 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1020 N 15 0 5 0 4 5 0 0 12 6 4 15 0 4 0 5 8 9 0 7 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1021 V 70 4 0 0 0 0 7 6 0 0 0 0 5 4 0 0 0 4 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1022 V 2 0 0 0 0 0 0 31 4 51 7 0 0 0 0 0 0 5 0 0 DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic":DOMAIN:/note="TIR":TOPO_DOM:/note="Cytoplasmic" 1023 L 3 0 0 0 0 16 0 0 0 43 0 0 22 0 0 0 16 0 0 0 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 1024 T 9 0 7 0 0 0 0 0 13 9 4 0 0 0 15 14 20 10 0 0 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 1025 E 0 0 24 31 0 0 0 0 14 0 0 0 9 0 14 0 0 8 0 0 TOPO_DOM:/note="Cytoplasmic":TOPO_DOM:/note="Cytoplasmic" 1026 N 0 0 3 9 0 0 0 0 5 0 0 65 0 5 0 8 6 0 0 0 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1027 D 10 0 7 0 0 10 13 0 9 0 0 3 0 2 9 32 0 6 0 0 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1028 S 18 0 0 6 0 9 16 0 5 0 0 11 0 0 12 14 0 8 0 0 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1029 R 9 0 0 6 17 10 12 0 21 0 0 0 0 8 18 0 0 0 0 0 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1030 Y 0 0 0 10 19 0 0 0 0 0 0 14 0 0 12 0 0 0 0 45 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1031 N 0 0 7 0 0 0 0 0 0 0 0 61 0 0 0 28 0 0 0 4 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1032 N 0 0 9 0 0 0 0 0 0 0 0 50 0 34 6 0 0 0 0 0 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1033 M 0 0 0 0 0 0 0 0 18 10 19 25 0 0 0 0 0 28 0 0 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1034 Y 18 0 0 0 44 0 0 0 0 0 0 0 0 0 18 0 0 0 0 20 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1035 V 0 25 0 0 0 18 0 10 19 0 0 0 0 0 0 0 0 28 0 0 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1036 D 0 0 23 22 0 0 0 0 0 0 0 0 0 36 0 0 0 20 0 0 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1037 S 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 62 22 0 0 0 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1038 I 0 0 0 0 0 0 0 51 0 0 0 0 0 0 0 0 0 49 0 0 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1039 K 0 0 0 0 0 0 0 0 50 0 0 0 0 0 50 0 0 0 0 0 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1040 Q 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic" 1041 Y 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 TOPO_DOM:/note="Cytoplasmic":DISORDER:predicted by DISOPRED:TOPO_DOM:/note="Cytoplasmic"