Contact Molecules for Homologous Proteins | ||||
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PID | QueryLength | Homolgous Sequence in PDB | UniProt Query | TITLE |
1122913 | 132 | 0 | Q01629(IFM2_HUMAN) | RecName: Full=Interferon-induced transmembrane protein 2 ;AltName: Full=Dispanin subfamily A member 2c; Short=DSPA2c;AltName: Full=Interferon-inducible protein 1-8D; |
QUERYSEQ |
MNHIVQTFSPVNSGQPPNYEMLKEEQEVAMLGVPHNPAPPMSTVIHIRSETSVPDHVVWSLFNTLFMNTCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGIFMTILLIIIPVLVVQAQR |
[n]:site number of query sequence. [a]:amino acid of query sequence. [s]:predicted secondary structure. [e]:predicted exposed/buried. [acc]:predicted relative accesssibility(%). [pdb]:PDB code of homologous structure. [contact_mols]:predicted binding molecules [observed aa]:Observed amino acids among homologous sequences. [feature table]:UniProt Feature Table [variant]:UniProt Human Variant.
n | a | s | e | acc | pdb | contact_mols | observed aa | feature table | variant |
1 | M | - | - | - | - | M |
MOD_RES /note="N-acetylmethionine" TOPO_DOM /note="Cytoplasmic" MOD_RES /note="N-acetylmethionine" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
2 | N | - | - | - | - | NS |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
3 | H | - | - | - | - | H |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
4 | I | - | - | - | - | TNI |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
5 | V | - | - | - | - | VS |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
6 | Q | - | - | - | - | QK |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
7 | T | - | - | - | - | TA |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
8 | F | - | - | - | - | FKD |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
9 | S | - | - | - | - | STL |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
10 | P | - | - | - | - | PVSA |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
11 | V | - | - | - | - | VPRTA |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
12 | N | - | - | - | - | ANS |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
13 | S | - | - | - | - | SNAG |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
14 | G | - | - | - | - | G |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
15 | Q | - | - | - | - | AQVL |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
16 | P | - | - | - | - | P |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
17 | P | - | - | - | - | PQ |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
18 | N | - | - | - | - | NARS |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
19 | Y | - | - | - | - | YCL |
MOD_RES /note="Phosphotyrosine" MUTAGEN /note="Y->F,A: Loss of phosphorylation. Accumulates at the plasma membrane. Increases infection with influenza A virus and SARS-CoV-2. Increases anti-HCV properties." ECO:0000269|PubMed:33563656" TOPO_DOM /note="Cytoplasmic" MOD_RES /note="Phosphotyrosine" MUTAGEN /note="Y->F,A: Loss of phosphorylation. Accumulates at the plasma membrane. Increases infection with influenza A virus and SARS-CoV-2. Increases anti-HCV properties." ECO:0000269|PubMed:33563656" TOPO_DOM /note="Cytoplasmic" | ||
20 | E | - | - | - | - | EKQ |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
21 | M | - | - | - | - | MKHTR |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
22 | L | - | - | - | - | LIPH |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
23 | K | - | - | - | - | KVA |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
24 | E | - | - | - | - | E |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
25 | E | - | - | - | - | EKQ |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
26 | Q | - | - | - | - | DKHQY |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
27 | E | - | - | - | - | ERTGK |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
28 | V | - | - | - | - | VIM |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
29 | A | - | - | - | - | ATGV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
30 | M | - | - | - | - | VREMAGLSDFHIKNPQTY |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
31 | L | - | - | - | - | LAMDEFGIKNPQRSTVY |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
32 | G | - | - | - | - | GHALDEFIKNPQRSTVY |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
33 | V | - | - | - | - | AGVSEPLDFIKNQRTY |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | V->A:(27.0 %):LB/B - dbSNP:rs1058900 | |
34 | P | - | - | - | - | PGALDEFIKNQRSTVY |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
35 | H | - | - | - | - | HSPALDEFGIKNQRTVY |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
36 | N | - | - | - | - | NPIGSADEFKLQRTV |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
37 | P | - | - | - | - | PGSTADEFIKLNQRV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
38 | A | - | - | - | - | ASPTILDEFGKNQRVY |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
39 | P | - | - | - | - | PSLVADEFGIKNQRTY |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
40 | P | - | - | - | - | PRVALDEFGIKNQSTY |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
41 | M | - | - | - | - | RGTMALDEFIKNPQSVY |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | M->T:(20.0 %):LB/B - dbSNP:rs14408 | |
42 | S | - | - | - | - | STADEFGIKLNPQRV |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
43 | T | - | - | - | - | TLADEFGIKNPQRSV |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
44 | V | - | - | - | - | VSTADEFGIKLNPQR |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
45 | I | - | - | - | - | IRADEFGKLNPQSTV |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
46 | H | - | - | - | - | HNEADFGIKLPQRSTV |
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" | ||
47 | I | - | - | - | - | IPMVADEFGKLNQRST |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
48 | R | - | - | - | - | SYRPHAGLDEFIKNQTV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
49 | S | - | - | - | - | SPRADEFGIKLNQTV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
50 | E | - | - | - | - | EQDKAFGILNPRSTV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
51 | T | - | - | - | - | TLVIADEFGKNPQRS |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
52 | S | - | - | - | - | SATDEFGIKLNPQRV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
53 | V | - | - | - | - | VGITADEKLNPQRS |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
54 | P | - | - | - | - | PNRADEGIKLQSTV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
55 | D | - | - | - | - | DH |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
56 | H | - | - | - | - | HY |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
57 | V | - | - | - | - | VMILY |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
58 | V | - | - | - | - | VILMP |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
59 | W | - | - | - | - | WLE |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
60 | S | - | - | - | - | SA |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
61 | L | - | - | - | - | ILV |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
62 | F | - | - | - | - | FL |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
63 | N | - | - | - | - | NSVLADEFGIKPQRTY |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
64 | T | - | - | - | - | TSFL |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
65 | L | - | - | - | - | LCVFM |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
66 | F | - | - | - | - | FY |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
67 | M | - | - | - | - | LMCFADEGIKNPQRSTV |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
68 | N | - | - | - | - | NPADEFGIKLQRSTV |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
69 | T | - | - | - | - | FMLPVATWDEGIKNQRS |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
70 | C | - | - | - | - | CW |
LIPID /note="S-palmitoyl cysteine" MUTAGEN /note="CC->AA: No effect on anti-HCV activity. Partial loss of endosomal location." INTRAMEM /note="Helical" LIPID /note="S-palmitoyl cysteine" MUTAGEN /note="CC->AA: No effect on anti-HCV activity. Partial loss of endosomal location." INTRAMEM /note="Helical" | ||
71 | C | - | - | - | - | CP |
LIPID /note="S-palmitoyl cysteine" MUTAGEN /note="CC->AA: No effect on anti-HCV activity. Partial loss of endosomal location." INTRAMEM /note="Helical" LIPID /note="S-palmitoyl cysteine" MUTAGEN /note="CC->AA: No effect on anti-HCV activity. Partial loss of endosomal location." INTRAMEM /note="Helical" | ||
72 | L | - | - | - | - | LV |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
73 | G | - | - | - | - | GN |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
74 | F | - | - | - | - | FLI |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
75 | I | - | - | - | - | IVLT |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
76 | A | - | - | - | - | A |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
77 | F | - | - | - | - | FLIYM |
INTRAMEM /note="Helical" INTRAMEM /note="Helical" | ||
78 | A | - | - | - | - | AVI |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
79 | Y | - | - | - | - | YFH |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
80 | S | - | - | - | - | SA |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
81 | V | - | - | - | - | VHLI |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
82 | K | - | - | - | - | KEM |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
83 | S | - | - | - | - | SAV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
84 | R | - | - | - | - | R |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
85 | D | - | - | - | - | DAN |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
86 | R | - | - | - | - | RASKQ |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
87 | K | - | - | - | - | KL |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
88 | M | - | - | - | - | MGQLV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
89 | V | - | - | - | - | VQRLA |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
90 | G | - | - | - | - | GN |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
91 | D | - | - | - | - | DN |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
92 | V | - | - | - | - | VLT |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
93 | T | - | - | - | - | TEADNV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
94 | G | - | - | - | - | GQA |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
95 | A | - | - | - | - | A |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
96 | Q | - | - | - | - | QREV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
97 | A | - | - | - | - | EARHQ |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
98 | Y | - | - | - | - | YALDF |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
99 | A | - | - | - | - | AGS |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
100 | S | - | - | - | - | SRK |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
101 | T | - | - | - | - | TKV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
102 | A | - | - | - | - | AT |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
103 | K | - | - | - | - | KR |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
104 | C | - | - | - | - | CLS |
LIPID /note="S-palmitoyl cysteine" MUTAGEN /note="C->A: Loss of anti-HCV activity. Partial loss of endosomal location." TOPO_DOM /note="Cytoplasmic" LIPID /note="S-palmitoyl cysteine" MUTAGEN /note="C->A: Loss of anti-HCV activity. Partial loss of endosomal location." TOPO_DOM /note="Cytoplasmic" | ||
105 | L | - | - | - | - | LFY |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
106 | N | - | - | - | - | NSV |
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" | ||
107 | I | - | - | - | - | IL |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
108 | W | - | - | - | - | FVWLTSA |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
109 | A | - | - | - | - | AST |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
110 | L | - | - | - | - | LSAT |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
111 | I | - | - | - | - | VIALMF |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
112 | L | - | - | - | - | LFG |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
113 | G | - | - | - | - | GAST |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
114 | I | - | - | - | - | IVA |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
115 | F | - | - | - | - | LFS |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
116 | M | - | - | - | - | MCVIT |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
117 | T | - | - | - | - | ITSA |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
118 | I | - | - | - | - | IT |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
119 | L | - | - | - | - | LSAVG |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
120 | L | - | - | - | - | VWLSIF |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
121 | I | - | - | - | - | IFVC |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | I->V:(21.0 %):LB/B - dbSNP:rs1059091 | |
122 | I | - | - | - | - | IVL |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
123 | I | - | - | - | - | IFVL |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
124 | P | - | - | - | - | PL |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
125 | V | - | - | - | - | V |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
126 | L | - | - | - | - | LF |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
127 | V | - | - | - | - | IV |
TRANSMEM /note="Helical" TRANSMEM /note="Helical" | ||
128 | V | - | - | - | - | FV |
TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular" | ||
129 | Q | - | - | - | - | Q |
TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular" | ||
130 | A | - | - | - | - | A |
TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular" | ||
131 | Q | - | - | - | - | HQ |
TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular" | ||
132 | R | - | - | - | - | R |
TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular" |