Contact Molecules for Homologous Proteins


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PID QueryLength Homolgous Sequence in PDB UniProt Query TITLE
1122913 132 0 Q01629(IFM2_HUMAN) RecName: Full=Interferon-induced transmembrane protein 2 ;AltName: Full=Dispanin subfamily A member 2c; Short=DSPA2c;AltName: Full=Interferon-inducible protein 1-8D;
QUERYSEQ
MNHIVQTFSPVNSGQPPNYEMLKEEQEVAMLGVPHNPAPPMSTVIHIRSETSVPDHVVWSLFNTLFMNTCCLGFIAFAYSVKSRDRKMVGDVTGAQAYASTAKCLNIWALILGIFMTILLIIIPVLVVQAQR
[BLAST file for PDB] (plain) (bar) (multiple alignment) [BLAST for UniProt: (plain) (bar) (multiple alignment) (PSSM file) ]
  [n]:site number of query sequence.  [a]:amino acid of query sequence.  [s]:predicted secondary structure.
  [e]:predicted exposed/buried.  [acc]:predicted relative accesssibility(%).  [pdb]:PDB code of homologous structure.
  [contact_mols]:predicted binding molecules  [observed aa]:Observed amino acids among homologous sequences.  [feature table]:UniProt Feature Table
  [variant]:UniProt Human Variant.
n a s e acc pdb contact_mols observed aa feature table variant
1M----
M
MOD_RES /note="N-acetylmethionine" TOPO_DOM /note="Cytoplasmic" MOD_RES /note="N-acetylmethionine" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
2N----
NS
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
3H----
H
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
4I----
TNI
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
5V----
VS
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
6Q----
QK
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
7T----
TA
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
8F----
FKD
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
9S----
STL
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
10P----
PVSA
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
11V----
VPRTA
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
12N----
ANS
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
13S----
SNAG
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
14G----
G
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
15Q----
AQVL
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
16P----
P
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
17P----
PQ
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
18N----
NARS
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
19Y----
YCL
MOD_RES /note="Phosphotyrosine" MUTAGEN /note="Y->F,A: Loss of phosphorylation. Accumulates at the plasma membrane. Increases infection with influenza A virus and SARS-CoV-2. Increases anti-HCV properties." ECO:0000269|PubMed:33563656" TOPO_DOM /note="Cytoplasmic" MOD_RES /note="Phosphotyrosine" MUTAGEN /note="Y->F,A: Loss of phosphorylation. Accumulates at the plasma membrane. Increases infection with influenza A virus and SARS-CoV-2. Increases anti-HCV properties." ECO:0000269|PubMed:33563656" TOPO_DOM /note="Cytoplasmic"
20E----
EKQ
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
21M----
MKHTR
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
22L----
LIPH
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
23K----
KVA
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
24E----
E
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
25E----
EKQ
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
26Q----
DKHQY
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
27E----
ERTGK
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
28V----
VIM
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
29A----
ATGV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
30M----
VREMAGLSDFHIKNPQTY
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
31L----
LAMDEFGIKNPQRSTVY
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
32G----
GHALDEFIKNPQRSTVY
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
33V----
AGVSEPLDFIKNQRTY
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic" V->A:(27.0 %):LB/B - dbSNP:rs1058900
34P----
PGALDEFIKNQRSTVY
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
35H----
HSPALDEFGIKNQRTVY
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
36N----
NPIGSADEFKLQRTV
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
37P----
PGSTADEFIKLNQRV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
38A----
ASPTILDEFGKNQRVY
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
39P----
PSLVADEFGIKNQRTY
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
40P----
PRVALDEFGIKNQSTY
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
41M----
RGTMALDEFIKNPQSVY
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic" M->T:(20.0 %):LB/B - dbSNP:rs14408
42S----
STADEFGIKLNPQRV
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
43T----
TLADEFGIKNPQRSV
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
44V----
VSTADEFGIKLNPQR
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
45I----
IRADEFGKLNPQSTV
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
46H----
HNEADFGIKLPQRSTV
TOPO_DOM /note="Cytoplasmic" DISORDER predicted by DISOPRED TOPO_DOM /note="Cytoplasmic"
47I----
IPMVADEFGKLNQRST
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
48R----
SYRPHAGLDEFIKNQTV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
49S----
SPRADEFGIKLNQTV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
50E----
EQDKAFGILNPRSTV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
51T----
TLVIADEFGKNPQRS
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
52S----
SATDEFGIKLNPQRV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
53V----
VGITADEKLNPQRS
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
54P----
PNRADEGIKLQSTV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
55D----
DH
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
56H----
HY
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
57V----
VMILY
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
58V----
VILMP
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
59W----
WLE
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
60S----
SA
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
61L----
ILV
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
62F----
FL
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
63N----
NSVLADEFGIKPQRTY
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
64T----
TSFL
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
65L----
LCVFM
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
66F----
FY
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
67M----
LMCFADEGIKNPQRSTV
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
68N----
NPADEFGIKLQRSTV
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
69T----
FMLPVATWDEGIKNQRS
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
70C----
CW
LIPID /note="S-palmitoyl cysteine" MUTAGEN /note="CC->AA: No effect on anti-HCV activity. Partial loss of endosomal location." INTRAMEM /note="Helical" LIPID /note="S-palmitoyl cysteine" MUTAGEN /note="CC->AA: No effect on anti-HCV activity. Partial loss of endosomal location." INTRAMEM /note="Helical"
71C----
CP
LIPID /note="S-palmitoyl cysteine" MUTAGEN /note="CC->AA: No effect on anti-HCV activity. Partial loss of endosomal location." INTRAMEM /note="Helical" LIPID /note="S-palmitoyl cysteine" MUTAGEN /note="CC->AA: No effect on anti-HCV activity. Partial loss of endosomal location." INTRAMEM /note="Helical"
72L----
LV
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
73G----
GN
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
74F----
FLI
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
75I----
IVLT
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
76A----
A
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
77F----
FLIYM
INTRAMEM /note="Helical" INTRAMEM /note="Helical"
78A----
AVI
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
79Y----
YFH
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
80S----
SA
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
81V----
VHLI
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
82K----
KEM
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
83S----
SAV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
84R----
R
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
85D----
DAN
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
86R----
RASKQ
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
87K----
KL
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
88M----
MGQLV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
89V----
VQRLA
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
90G----
GN
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
91D----
DN
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
92V----
VLT
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
93T----
TEADNV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
94G----
GQA
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
95A----
A
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
96Q----
QREV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
97A----
EARHQ
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
98Y----
YALDF
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
99A----
AGS
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
100S----
SRK
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
101T----
TKV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
102A----
AT
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
103K----
KR
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
104C----
CLS
LIPID /note="S-palmitoyl cysteine" MUTAGEN /note="C->A: Loss of anti-HCV activity. Partial loss of endosomal location." TOPO_DOM /note="Cytoplasmic" LIPID /note="S-palmitoyl cysteine" MUTAGEN /note="C->A: Loss of anti-HCV activity. Partial loss of endosomal location." TOPO_DOM /note="Cytoplasmic"
105L----
LFY
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
106N----
NSV
TOPO_DOM /note="Cytoplasmic" TOPO_DOM /note="Cytoplasmic"
107I----
IL
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
108W----
FVWLTSA
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
109A----
AST
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
110L----
LSAT
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
111I----
VIALMF
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
112L----
LFG
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
113G----
GAST
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
114I----
IVA
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
115F----
LFS
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
116M----
MCVIT
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
117T----
ITSA
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
118I----
IT
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
119L----
LSAVG
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
120L----
VWLSIF
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
121I----
IFVC
TRANSMEM /note="Helical" TRANSMEM /note="Helical" I->V:(21.0 %):LB/B - dbSNP:rs1059091
122I----
IVL
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
123I----
IFVL
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
124P----
PL
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
125V----
V
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
126L----
LF
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
127V----
IV
TRANSMEM /note="Helical" TRANSMEM /note="Helical"
128V----
FV
TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
129Q----
Q
TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
130A----
A
TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
131Q----
HQ
TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"
132R----
R
TOPO_DOM /note="Extracellular" TOPO_DOM /note="Extracellular"