Summary for the 58-th Site(M)

PID QueryLength FocusSite TITLE
29141 61 58 M RecName: Full=ORF6 protein; Short=ORF6;AltName: Full=Accessory protein 6;AltName: Full=Non-structural protein 6; Short=ns6;AltName: Full=Protein X3;
UniProt Information
AC/IDAC:P0DTC6 ID:NS6_SARS2
Feature Table for 58-th site MUTAGEN: /note="M->A: Loss of interaction with human NUP98-RAE1 complex which suppresses the mRNA accumulation in the nucleus, the down-regulation of protein expression of newly transcribed genes in the host cell and blockade on nuclear import on a broad range of host factors." ECO:0000269|PubMed:35096974"
MUTAGEN: /note="M->R: Complete loss of binding to the NUP98-RAE1 complex and IFN antagonistic function." ECO:0000269|PubMed:35096974"
MUTAGEN: /note="Missing: Loss of interaction with human NUP98-RAE1 complex which suppresses the down-regulation of protein expression of newly transcribed genes in the host cell."
MUTAGEN: /note="Missing: Loss of interaction with human NUP98-RAE1 complex which suppresses the down-regulation of protein expression of newly transcribed genes in the host cell."
CHAIN: /note="ORF6 protein" /id="PRO_0000449653"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
M:100% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
7vph (coil) e (exposed) 78.3
3D Complex Information
Predicted Bind Molecules
hetero:6
Templates for 3D complexes
hetero [75050:RAE1L_HUMAN ] 7f60_E_1_A_1 7f60_F_1_B_1 7vph_I_1_C_1 7vph_J_1_E_1 7vph_K_1_G_1 7vph_L_1_A_1


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