Summary for the 1165-th Site(S)
PID QueryLength FocusSite TITLE
16285 1170 1165 S RecName: Full=Integrin alpha-L ;AltName: Full=CD11 antigen-like family member A;AltName: Full=Leukocyte adhesion glycoprotein LFA-1 alpha chain; Short=LFA-1A;AltName: Full=Leukocyte function-associated molecule 1 alpha chain;AltName: CD_antigen=CD11a;Flags: Precursor;
UniProt Information
AC/IDAC:P20701 ID:ITAL_HUMAN
Feature Table for 1165-th site MOD_RES: /note="Phosphoserine"
MUTAGEN: /note="S->A: Abolishes phosphorylation and MEM-83-activated T-cell adhesion to ICAM1. Abolishes integrin alpha-L/beta-2 activation by CXCL12 and TERF2IP/RAP1. Does not affect heterodimerization of cell surface expression. Does not affect TCR- or phorbol ester-activated T-cell adhesion to ICAM1."
HELIX:
COMPBIAS: /note="Basic and acidic residues"
REGION: /note="Disordered"
TOPO_DOM: /note="Cytoplasmic"
CHAIN: /note="Integrin alpha-L" /id="PRO_0000016292"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
G:50% S:50%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
2k8o H (alpha-helix) e (exposed) 21.1


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