Summary for the 74-th Site(R)

PID QueryLength FocusSite TITLE
20585 425 74 R RecName: Full=Mothers against decapentaplegic homolog 3; Short=MAD homolog 3; Short=Mad3; Short=Mothers against DPP homolog 3; Short=hMAD-3;AltName: Full=JV15-2;AltName: Full=SMAD family member 3; Short=SMAD 3; Short=Smad3; Short=hSMAD3;
UniProt Information
AC/IDAC:P84022 ID:SMAD3_HUMAN
Feature Table for 74-th site MUTAGEN: /note="R->D: Reduced interaction with JUN. Loss of transcriptional activity and cooperation with JUN."
VAR_SEQ: /note="Missing (in isoform 3)" /id="VSP_043793"
DOMAIN: /note="MH1"
VAR_SEQ: /note="Missing (in isoform 4)" /id="VSP_045348"
CHAIN: /note="Mothers against decapentaplegic homolog 3" /id="PRO_0000090856"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
R:68% K:14% D:10% E:7% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
1ozj (coil) e (exposed) 47.8
3D Complex Information
Predicted Bind Molecules
nucleotide:67
Templates for 3D complexes
nucleotide [tatgtctagactgaxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 1mhd_C_1_B_1 [cagtctagacataxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 1mhd_D_1_A_1 [tcagtctagacatacxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 1ozj_C_1_A_1 1ozj_D_1_A_1 [gtatgtctagactgaxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 1ozj_C_1_B_1 1ozj_D_1_B_1 3kmp_A_1_D_1 [atcagtctagacataxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 3kmp_B_1_C_1 [tgcagtctagactgcaxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 3qsv_A_1_E_1 3qsv_A_1_F_1 3qsv_B_1_G_1 3qsv_B_1_H_1 3qsv_C_1_G_1 3qsv_C_1_H_1 3qsv_D_1_E_1 3qsv_D_1_F_1 [atgcgggcgcgcccgcatxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 5mey_A_1_B_2 5mey_A_2_B_1 5nm9_A_1_D_1 5nm9_A_3_D_3 5nm9_B_1_C_3 5nm9_B_2_C_1 [xgcaggctagcctgcaxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 5mez_A_1_D_1 [acgggccgcggcccgtxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 5mf0_A_1_C_1 5mf0_A_1_D_1 5mf0_B_2_C_1 [tgcaggcgcgcctgcaxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 5od6_A_1_C_1 5od6_A_1_D_1 6fzs_A_1_D_1 6fzs_B_2_C_2 6fzt_A_1_C_1 6fzt_A_1_D_1 6fzt_B_2_C_2 6fzt_B_2_D_2 6tbz_A_1_C_1 6zmn_A_1_C_2 6zmn_B_1_D_1 [xxxaggctagcctgcaxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 5odg_A_1_C_1 5odg_A_3_C_3 5odg_B_1_C_3 5odg_B_2_C_1 [tgcaggctagcctxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 5odg_A_1_D_1 5odg_A_3_D_3 5odg_B_1_D_3 5odg_B_2_D_1 [xgtatgtctagactgaxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 5x6g_A_1_D_1 [atcagtctagacataxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 5x6g_B_1_C_1 [gtatggcgccatacxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 5x6h_A_1_B_1 5x6h_A_1_B_2 5x6h_A_2_B_1 5x6h_A_2_B_2 [atcagactgccggcagtctataxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 5x6m_A_1_B_1 5x6m_D_1_B_1 5x6m_E_1_F_1 5x6m_H_1_F_1 [ttatagactgccggcagtctgaxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 5x6m_A_1_C_1 5x6m_D_1_C_1 5x6m_E_1_G_1 5x6m_H_1_G_1 [gagtgtctgcagacactcxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 6h3r_A_1_C_1 6h3r_A_1_D_1 6h3r_B_1_C_2 6h3r_B_1_D_2 [tgcaggctagcctgcaxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx ] 6tce_A_1_B_1 6tce_A_1_B_2 6tce_A_2_B_1 6tce_A_2_B_2


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