Summary for the 44-th Site(K)
PID QueryLength FocusSite TITLE
20585 425 44 K RecName: Full=Mothers against decapentaplegic homolog 3; Short=MAD homolog 3; Short=Mad3; Short=Mothers against DPP homolog 3; Short=hMAD-3;AltName: Full=JV15-2;AltName: Full=SMAD family member 3; Short=SMAD 3; Short=Smad3; Short=hSMAD3;
UniProt Information
AC/IDAC:P84022 ID:SMAD3_HUMAN
Feature Table for 44-th site MUTAGEN: /note="K->A: Little effect on interaction with DNA or JUN. Abolishes interaction with JUN; when associated with A-40; A-41 and A-43."
HELIX:
VAR_SEQ: /note="MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELE KAITTQNVNTKCITIP -> MSCLHPRQTWKGAALVHRKAWWMG (in isoform 2)" /id="VSP_042900"
VAR_SEQ: /note="Missing (in isoform 3)" /id="VSP_043793"
DOMAIN: /note="MH1"
VAR_SEQ: /note="Missing (in isoform 4)" /id="VSP_045348"
CHAIN: /note="Mothers against decapentaplegic homolog 3" /id="PRO_0000090856"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
K:56% E:36% D:8%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
1ozj H (alpha-helix) e (exposed) 78.8


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