Summary for the 424-th Site(V)
PID QueryLength FocusSite TITLE
20585 425 424 V RecName: Full=Mothers against decapentaplegic homolog 3; Short=MAD homolog 3; Short=Mad3; Short=Mothers against DPP homolog 3; Short=hMAD-3;AltName: Full=JV15-2;AltName: Full=SMAD family member 3; Short=SMAD 3; Short=Smad3; Short=hSMAD3;
UniProt Information
AC/IDAC:P84022 ID:SMAD3_HUMAN
Feature Table for 424-th site MUTAGEN: /note="SSVS->AAVA: Does not abolish protein nuclear export. Abolishes almost completely acetylation." ECO:0000269|PubMed:16449645, ECO:0000269|PubMed:16862174"
MUTAGEN: /note="SSVS->EEVE: Forms heterotrimers." ECO:0000269|PubMed:16449645, ECO:0000269|PubMed:16862174"
MUTAGEN: /note="SSVS->RRVR: Diminishes cargo protein export." ECO:0000269|PubMed:16449645, ECO:0000269|PubMed:16862174"
DOMAIN: /note="MH2"
CHAIN: /note="Mothers against decapentaplegic homolog 3" /id="PRO_0000090856"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
V:74% I:18% M:9%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
6m64 (coil) e (exposed) 84.1
3D Complex Information
Predicted Bind Molecules
hetero:2 homo:17
Templates for 3D complexes
hetero [58293:SMAD4_HUMAN ] 1u7f_A_1_B_1 1u7v_A_1_C_1 homo [50456:SMAD1_HUMAN ] 1khu_A_1_C_1 1khu_B_1_A_1 1khu_C_1_B_1 [47815:SMAD2_HUMAN ] 1khx_A_1_A_3 1khx_A_2_A_1 1khx_A_3_A_2 1u7f_C_1_A_1 1u7v_B_1_A_1 6m64_A_1_E_1 6zvq_A_1_A_3 6zvq_A_2_A_1 6zvq_A_3_A_2 [46223:MAD_DROME ] 3gmj_A_1_A_2 3gmj_A_2_A_3 3gmj_A_3_A_1 3gmj_B_1_D_1 3gmj_C_1_B_1


[Back to SiteTable]
[Back to Search Page]
[Back to Top Page]