Summary for the 333-rd Site(K)
PID QueryLength FocusSite TITLE
20585 425 333 K RecName: Full=Mothers against decapentaplegic homolog 3; Short=MAD homolog 3; Short=Mad3; Short=Mothers against DPP homolog 3; Short=hMAD-3;AltName: Full=JV15-2;AltName: Full=SMAD family member 3; Short=SMAD 3; Short=Smad3; Short=hSMAD3;
UniProt Information
AC/IDAC:P84022 ID:SMAD3_HUMAN
Feature Table for 333-th site MUTAGEN: /note="K->R: No effect on acetylation. Completely abolishes acetylation and 97% reduction in transcriptional activity; when associated with R-341; R-378 and R-409."
STRAND:
DOMAIN: /note="MH2"
CHAIN: /note="Mothers against decapentaplegic homolog 3" /id="PRO_0000090856"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
K:75% R:16% H:9%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
1mk2 E (beta-strand) e (exposed) 61.8
3D Complex Information
Predicted Bind Molecules
hetero:22 homo:15 metal:1 precipitant:2
Templates for 3D complexes
hetero [13061:ZFYV9_HUMAN ] 1dev_A_1_B_1 1dev_C_1_D_1 1mk2_A_1_B_1 1mk2_A_2_B_2 [24378:SKI_HUMAN ] 1mr1_A_1_D_1 1mr1_B_1_C_1 [47815:SMAD3_HUMAN ] 1u7f_B_1_A_1 1u7v_C_1_A_1 [32252:SKIL_HUMAN ] 5c4v_A_1_D_1 5c4v_B_1_E_1 5c4v_C_1_F_1 [25915:THIO_ECOLI :FOXH1_HUMAN ] 5xoc_A_1_B_1 5xoc_A_2_B_2 5xoc_A_3_B_3 [33856:MAN1_HUMAN ] 5zoj_A_1_D_1 5zok_A_1_B_1 5zok_A_2_B_2 5zok_A_4_B_4 5zok_C_1_D_1 5zok_C_3_D_3 5zok_C_5_D_5 [33857:MAN1_HUMAN ] 5zoj_B_1_E_1 homo [47815:SMAD2_HUMAN ] 1khx_A_1_A_2 1khx_A_2_A_3 1khx_A_3_A_1 1u7f_A_1_C_1 1u7v_A_1_B_1 6m64_E_1_A_1 6zvq_A_1_A_2 6zvq_A_2_A_3 6zvq_A_3_A_1 [50456:SMAD1_HUMAN ] 5zok_A_1_A_2 5zok_A_2_A_4 5zok_A_4_A_1 5zok_C_1_C_5 5zok_C_3_C_1 5zok_C_5_C_3 metal [CL ] 7cd1_A_1_G_1 precipitant [SO4 ] 7cd1_B_1_I_1 7cd1_C_1_N_1


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