Summary for the 179-th Site(T)
PID QueryLength FocusSite TITLE
20585 425 179 T RecName: Full=Mothers against decapentaplegic homolog 3; Short=MAD homolog 3; Short=Mad3; Short=Mothers against DPP homolog 3; Short=hMAD-3;AltName: Full=JV15-2;AltName: Full=SMAD family member 3; Short=SMAD 3; Short=Smad3; Short=hSMAD3;
UniProt Information
AC/IDAC:P84022 ID:SMAD3_HUMAN
Feature Table for 179-th site MOD_RES: /note="Phosphothreonine; by CDK2, CDK4 and MAPK" ECO:0000269|PubMed:16156666, ECO:0000269|PubMed:19218245"
MUTAGEN: /note="T->V: Reduced phosphorylation, increased transcriptional and increased antiproliferative activities. Further increase in transcriptional and antiproliferative activities; when associated with V-8 and A-213." ECO:0000269|PubMed:16156666, ECO:0000269|PubMed:19218245"
REGION: /note="Disordered"
REGION: /note="Linker"
VAR_SEQ: /note="Missing (in isoform 4)" /id="VSP_045348"
CHAIN: /note="Mothers against decapentaplegic homolog 3" /id="PRO_0000090856"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
T:38% Q:18% P:13% A:11% S:6% L:2% R:1% N:1% D:1% E:1% G:1% I:1% K:1% F:1% Y:1% V:1%


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