Summary for the 92-nd Site(T)
PID QueryLength FocusSite TITLE
18353 805 92 T RecName: Full=Angiotensin-converting enzyme 2; EC=3.4.17.23 ;AltName: Full=Angiotensin-converting enzyme homolog ; Short=ACEH ;AltName: Full=Angiotensin-converting enzyme-related carboxypeptidase ; Short=ACE-related carboxypeptidase; EC=3.4.17.- ;AltName: Full=Metalloprotease MPROT15 ;Contains: RecName: Full=Processed angiotensin-converting enzyme 2 ;Flags: Precursor;
UniProt Information
AC/IDAC:Q9BYF1 ID:ACE2_HUMAN
Feature Table for 92-th site MUTAGEN: /note="T->Q: Increases slightly the interaction with RBD domain of SARS-CoV-2 spike protein."
HELIX:
VAR_SEQ: /note="MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNT NITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSED KSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRS EVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHT FEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQK PNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPT AWDLGKGDF -> MREAGWDKGG (in isoform 2)" /id="VSP_060903"
DOMAIN: /note="Peptidase M2"
CHAIN: /note="Processed angiotensin-converting enzyme 2" /id="PRO_0000292268"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Angiotensin-converting enzyme 2" /id="PRO_0000028570"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
T:38% D:26% K:17% L:7% Q:5% I:3% S:3%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
7v61 H (alpha-helix) e (exposed) 34.4
3D Complex Information
Predicted Bind Molecules
otherpoly:50 compound:98
Templates for 3D complexes
otherpoly [beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ] 2iul_A_1_B_1 [beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 2ydm_A_1_B_1 [2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ] 3bkk_A_1_B_1 3bkl_A_1_B_1 3l3n_A_1_B_1 4ca5_A_1_B_1 8e7m_A_1_D_1 [beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ] 4bzr_A_1_B_1 4c2o_A_1_B_1 4c2p_A_1_B_1 6h5w_A_1_C_1 7q27_A_1_B_1 [2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ] 6f9t_A_1_C_1 6zpu_A_1_C_1 [alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ] 6f9u_A_1_B_1 [2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 7ct5_D_1_BA_1 7ct5_E_1_GA_1 7ct5_F_1_LA_1 7drv_A_1_E_1 7drv_C_1_G_1 7fc3_B_1_D_1 7pki_A_1_C_1 7q4d_A_1_I_1 7q4d_B_1_O_1 7q4e_A_1_H_1 7wbq_A_1_E_1 7wbq_C_1_G_1 7y1y_D_1_EA_1 7y1y_E_1_JA_1 7y1y_F_1_OA_1 7y1z_D_1_EA_1 7y1z_E_1_JA_1 7y1z_F_1_OA_1 7y20_D_1_DA_1 7y20_E_1_IA_1 7y21_D_1_EA_1 7y21_E_1_JA_1 7y21_F_1_OA_1 8i91_A_1_F_1 8i91_C_1_M_1 8i92_A_1_F_1 8i92_C_1_M_1 8i9e_A_1_D_1 [alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose ] 7q28_A_1_B_1 7q29_A_1_B_1 7z70_A_1_B_1 [beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 7sn0_A_1_I_1 [beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 7sn0_B_1_O_1 [alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose ] 7whh_A_1_C_1 [alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 8if2_A_1_D_1 compound [NAG ] 2iux_A_1_C_1 6lzg_A_1_D_1 7c8k_A_1_D_1 7ddo_A_1_E_1 7ddp_A_1_E_1 7dqa_A_1_F_1 7dx4_A_1_F_1 7edj_D_1_DB_1 7efp_A_1_D_1 7eke_A_1_D_1 7ekh_A_1_D_1 7fc5_B_1_D_1 7fdh_A_1_D_1 7fdi_A_1_D_1 7kmb_A_1_H_1 7kms_A_1_R_1 7kms_E_1_JB_1 7kms_F_1_PB_1 7knb_D_1_BB_1 7kne_D_1_AB_1 7knh_C_1_MA_1 7kni_D_1_EB_1 7kni_E_1_JB_1 7kni_F_1_OB_1 7l0n_I_1_MA_1 7l0n_J_1_TA_1 7mjn_B_1_E_1 7nxc_A_1_D_1 7p19_C_1_K_1 7r11_A_1_H_1 7rpv_A_1_J_1 7rpv_C_1_Q_1 7sxx_D_1_RA_1 7sxy_B_1_E_1 7sxz_D_1_TA_1 7sy0_B_1_E_1 7sy1_D_1_TA_1 7sy2_B_1_E_1 7sy3_D_1_RA_1 7sy4_B_1_E_1 7sy5_D_1_XA_1 7sy5_E_1_DB_1 7sy5_F_1_JB_1 7sy6_B_1_E_1 7sy7_D_1_TA_1 7sy8_B_1_E_1 7t9k_D_1_UA_1 7t9k_E_1_AB_1 7t9l_B_1_E_1 7tew_B_1_E_1 7tex_D_1_RA_1 7tez_B_1_E_1 7tf0_D_1_RA_1 7vx4_A_1_E_1 7vx5_A_1_E_1 7wpa_D_1_KA_1 7wpo_A_1_H_1 7ws8_D_1_CA_1 7ws8_E_1_IA_1 7ws9_D_1_Z_1 7wsa_B_1_E_1 7xbf_A_1_F_1 7xbg_A_1_H_1 7xid_D_1_HB_1 7xid_E_1_OB_1 7xo7_D_1_QA_1 7ydi_A_1_F_1 7yeg_D_1_SA_1 7yeg_I_1_XA_1 7yeg_J_1_CB_1 7yr3_E_1_QB_1 7yv8_A_1_D_1 7zdq_A_1_D_1 8dlj_D_1_TA_1 8dlk_B_1_E_1 8dlm_D_1_RA_1 8dln_B_1_E_1 8dlp_D_1_XA_1 8dlp_E_1_DB_1 8dlp_F_1_JB_1 8dlq_B_1_E_1 8dlu_D_1_WA_1 8dlu_E_1_CB_1 8dlv_B_1_E_1 8dm5_D_1_TA_1 8dm5_E_1_ZA_1 8dm6_B_1_E_1 8fxb_C_1_F_1 8hfx_D_1_AB_1 8hfz_D_1_VA_1 8ify_E_1_SA_1 8u0t_A_1_C_1 8vko_D_1_AB_1 8vko_E_1_EB_1 8vko_F_1_IB_1 8vkp_B_1_G_1 8wgv_E_1_BB_1 [NDG ] 3d0g_A_1_E_1


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