Summary for the 84-th Site(P)
PID QueryLength FocusSite TITLE
18353 805 84 P RecName: Full=Angiotensin-converting enzyme 2; EC=3.4.17.23 ;AltName: Full=Angiotensin-converting enzyme homolog ; Short=ACEH ;AltName: Full=Angiotensin-converting enzyme-related carboxypeptidase ; Short=ACE-related carboxypeptidase; EC=3.4.17.- ;AltName: Full=Metalloprotease MPROT15 ;Contains: RecName: Full=Processed angiotensin-converting enzyme 2 ;Flags: Precursor;
UniProt Information
AC/IDAC:Q9BYF1 ID:ACE2_HUMAN
Feature Table for 84-th site REGION: /note="Interaction with SARS-CoV spike glycoprotein"
MUTAGEN: /note="MYP->NFS: Inhibits interaction with SARS-CoV spike glycoprotein."
VAR_SEQ: /note="MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNT NITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSED KSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRS EVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHT FEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQK PNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPT AWDLGKGDF -> MREAGWDKGG (in isoform 2)" /id="VSP_060903"
DOMAIN: /note="Peptidase M2"
CHAIN: /note="Processed angiotensin-converting enzyme 2" /id="PRO_0000292268"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Angiotensin-converting enzyme 2" /id="PRO_0000028570"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
D:42% P:13% S:10% R:7% V:7% N:6% Q:6% K:6% G:5%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
7v61 (coil) e (exposed) 45.0
3D Complex Information
Predicted Bind Molecules
hetero:2 otherpoly:18
Templates for 3D complexes
hetero [100295:SPIKE_SARS2 ] 7wk5_A_1_B_1 7wvp_A_1_B_1 otherpoly [beta-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 2x8y_A_1_B_1 2x8z_A_1_B_1 2x90_A_1_B_1 2x91_A_1_B_1 2x92_A_1_B_1 2x93_A_1_B_1 2x94_A_1_B_1 2x95_A_1_B_1 2x96_A_1_B_1 2x97_A_1_B_1 2xhm_A_1_B_1 3zqz_A_1_B_1 4aa1_A_1_C_1 4aa2_A_1_C_1 4asq_A_1_C_1 4asr_A_1_C_1 4ca7_A_1_B_1 4ca8_A_1_B_1


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