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| PID | QueryLength | FocusSite | TITLE |
| 18353 | 805 | 351 L | RecName: Full=Angiotensin-converting enzyme 2; EC=3.4.17.23 ;AltName: Full=Angiotensin-converting enzyme homolog ; Short=ACEH ;AltName: Full=Angiotensin-converting enzyme-related carboxypeptidase ; Short=ACE-related carboxypeptidase; EC=3.4.17.- ;AltName: Full=Metalloprotease MPROT15 ;Contains: RecName: Full=Processed angiotensin-converting enzyme 2 ;Flags: Precursor; |
| AC/ID | AC:Q9BYF1 ID:ACE2_HUMAN |
| Feature Table for 351-th site |
MUTAGEN: /note="L->F: Increases slightly the interaction with RBD domain of SARS-CoV-2 spike protein." STRAND: VAR_SEQ: /note="MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNT NITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSED KSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRS EVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHT FEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQK PNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPT AWDLGKGDF -> MREAGWDKGG (in isoform 2)" /id="VSP_060903" DOMAIN: /note="Peptidase M2" CHAIN: /note="Processed angiotensin-converting enzyme 2" /id="PRO_0000292268" TOPO_DOM: /note="Extracellular" CHAIN: /note="Angiotensin-converting enzyme 2" /id="PRO_0000028570" |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
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F:63% L:23% M:14% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 7v61 |
(coil) | b (buried) | 0.0 |
| Predicted Bind Molecules |
| hetero:6 precipitant:14 |
| Templates for 3D complexes |
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hetero [100295:SPIKE_SARS2
] 7wk5_A_1_B_1 7wvp_A_1_B_1 8t22_D_1_C_1 8wtj_D_1_B_1 [9677 ] 8tot_A_1_C_1 8tot_B_1_D_1
precipitant [PEG ] 6en5_A_1_V_1 6en5_B_1_NA_1 6en6_B_1_HA_1 6tt4_A_1_P_1 7q24_B_1_AA_1 7q25_A_1_N_1 8qfx_D_1_YB_1 [EDO ] 6en5_C_1_KB_1 6h5x_A_1_P_1 6qs1_A_1_L_1 6tt3_B_1_FA_1 7q24_A_1_O_1 7z6z_A_1_Q_1 [PG4 ] 8qhl_A_1_Q_1
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Summary for the 351-st Site(L)