Summary for the 309-th Site(K)
PID QueryLength FocusSite TITLE
18353 805 309 K RecName: Full=Angiotensin-converting enzyme 2; EC=3.4.17.23 ;AltName: Full=Angiotensin-converting enzyme homolog ; Short=ACEH ;AltName: Full=Angiotensin-converting enzyme-related carboxypeptidase ; Short=ACE-related carboxypeptidase; EC=3.4.17.- ;AltName: Full=Metalloprotease MPROT15 ;Contains: RecName: Full=Processed angiotensin-converting enzyme 2 ;Flags: Precursor;
UniProt Information
AC/IDAC:Q9BYF1 ID:ACE2_HUMAN
Feature Table for 309-th site MUTAGEN: /note="K->D: No effect on interaction with SARS-CoV spike glycoprotein."
HELIX:
VAR_SEQ: /note="MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNT NITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSED KSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRS EVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHT FEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQK PNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPT AWDLGKGDF -> MREAGWDKGG (in isoform 2)" /id="VSP_060903"
DOMAIN: /note="Peptidase M2"
CHAIN: /note="Processed angiotensin-converting enzyme 2" /id="PRO_0000292268"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Angiotensin-converting enzyme 2" /id="PRO_0000028570"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
K:36% Q:21% E:18% V:14% R:11%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
7v61 H (alpha-helix) e (exposed) 46.2
3D Complex Information
Predicted Bind Molecules
otherpoly:4 compound:31 metal:1 precipitant:35
Templates for 3D complexes
otherpoly [2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 7dmu_A_1_G_1 7dmu_C_1_K_1 8sph_A_1_H_1 [beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 7sn0_A_1_F_1 compound [NAG ] 2ajf_A_1_H_1 6m17_B_1_BA_1 6m17_E_1_IA_1 7ddp_A_1_F_1 7dwx_B_1_VB_1 7dwx_D_1_CC_1 7dx8_D_1_MB_1 7dx9_D_1_MB_1 7kj3_D_1_LB_1 7kj4_D_1_RB_1 7kj4_E_1_SB_1 7l0n_J_1_UA_1 7pki_A_1_G_1 7rpv_E_1_Z_1 7rpv_G_1_GA_1 7tn0_E_1_BA_1 7u0n_A_1_P_1 7vx5_A_1_F_1 7xbf_C_1_N_1 7yr2_A_1_R_1 8wrh_A_1_E_1 8wtd_A_1_E_1 [PE3 ] 6en5_A_1_GA_1 [XPE ] 6en5_D_1_ZB_1 6en6_C_1_MB_1 6h5x_A_1_L_1 6qs1_A_1_J_1 8qfx_D_1_WB_1 [PE8 ] 6f9r_B_1_CA_1 7q26_B_1_U_1 [12P ] 8qfx_A_1_T_1 metal [CL ] 7l0n_J_1_AB_1 precipitant [P6G ] 2xyd_B_1_T_1 3nxq_B_1_S_1 4bxk_B_1_Q_1 4bzs_A_1_L_1 4ufa_B_1_T_1 4ufb_A_1_W_1 5am8_A_1_X_1 5am8_B_1_GA_1 5am9_A_1_X_1 5am9_B_1_GA_1 5ama_A_1_V_1 [PEG ] 4ca6_B_1_R_1 4ufa_B_1_S_1 4ufb_B_1_EA_1 5am8_B_1_FA_1 5am9_B_1_FA_1 5ama_B_1_DA_1 5amb_B_1_T_1 5amc_B_1_U_1 6f9r_B_1_U_1 6tt3_A_1_O_1 7q24_A_1_I_1 7q25_A_1_M_1 7z6z_A_1_L_1 [EDO ] 6en5_A_1_X_1 6en6_A_1_V_1 6zpu_A_1_F_1 8qfx_C_1_BB_1 [PGE ] 6f9v_B_1_DA_1 6tt1_B_1_DA_1 7q26_B_1_T_1 [MXE ] 6zpq_B_1_KA_1 [P33 ] 7q24_A_1_J_1 [ACT ] 7z6z_B_1_MA_1 [1PE ] 8qhl_C_1_AA_1


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