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| PID | QueryLength | FocusSite | TITLE |
| 18353 | 805 | 271 W | RecName: Full=Angiotensin-converting enzyme 2; EC=3.4.17.23 ;AltName: Full=Angiotensin-converting enzyme homolog ; Short=ACEH ;AltName: Full=Angiotensin-converting enzyme-related carboxypeptidase ; Short=ACE-related carboxypeptidase; EC=3.4.17.- ;AltName: Full=Metalloprotease MPROT15 ;Contains: RecName: Full=Processed angiotensin-converting enzyme 2 ;Flags: Precursor; |
| AC/ID | AC:Q9BYF1 ID:ACE2_HUMAN |
| Feature Table for 271-th site |
MUTAGEN: /note="W->Q: About 95% loss of angiotensin I cleavage." STRAND: VAR_SEQ: /note="MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNT NITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSED KSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRS EVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHT FEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQK PNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPT AWDLGKGDF -> MREAGWDKGG (in isoform 2)" /id="VSP_060903" DOMAIN: /note="Peptidase M2" CHAIN: /note="Processed angiotensin-converting enzyme 2" /id="PRO_0000292268" TOPO_DOM: /note="Extracellular" CHAIN: /note="Angiotensin-converting enzyme 2" /id="PRO_0000028570" |
Percentages of Amino Acids in Homologous Proteins
 [show alignment]
|
W:86% D:14% |
| Template For Monomer | predicted SecStr | predicted ExpBur | Predicted Relative Acc(%) |
 7v61 |
S (bend) | b (buried) | 13.9 |
| Predicted Bind Molecules |
| metal:1 precipitant:5 |
| Templates for 3D complexes |
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metal [CL ] 8df5_F_1_JB_1
precipitant [GOL ] 3bkl_A_1_L_1 [ACT ] 4aph_A_1_J_1 [EDO ] 6en6_B_1_KA_1 [PEG ] 6f9t_A_1_O_1 [BO3 ] 7q27_A_1_N_1
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Summary for the 271-st Site(W)