Summary for the 295-th Site(S)

PID QueryLength FocusSite TITLE
3025 967 295 S RecName: Full=Aminopeptidase N ; Short=AP-N; Short=hAPN; EC=3.4.11.2 ;AltName: Full=Alanyl aminopeptidase;AltName: Full=Aminopeptidase M; Short=AP-M;AltName: Full=Microsomal aminopeptidase;AltName: Full=Myeloid plasma membrane glycoprotein CD13;AltName: Full=gp150;AltName: CD_antigen=CD13;
UniProt Information
AC/IDAC:P15144 ID:AMPN_HUMAN
Feature Table for 295-th site REGION: /note="Necessary and sufficient to mediate interaction with HCoV-229E" ECO:0000269|PubMed:8887485"
MUTAGEN: /note="DYVEKQAS->QSVEETAQ: No change in receptor activity and HCoV-229E infection."
MUTAGEN: /note="DYVEKQAS->QSVNEQAQ: No change in receptor activity and HCoV-229E infection."
MUTAGEN: /note="DYVEKQAS->QSVNETAQ: Complete loss of receptor activity and blocks HCoV-229E infection. No loss of enzymatic activity."
REGION: /note="Metalloprotease"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Aminopeptidase N" /id="PRO_0000095081"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
K:20% P:13% S:12% G:10% R:8% T:8% A:6% D:5% E:5% N:4% V:3% Q:2% C:1% L:1% F:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5lhd T (Hbond turn) e (exposed) 102.3
3D Complex Information
Predicted Bind Molecules
otherpoly:1
Templates for 3D complexes
otherpoly [2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 7zyf_A_1_F_1


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