Summary for the 293-rd Site(Q)

PID QueryLength FocusSite TITLE
3025 967 293 Q RecName: Full=Aminopeptidase N ; Short=AP-N; Short=hAPN; EC=3.4.11.2 ;AltName: Full=Alanyl aminopeptidase;AltName: Full=Aminopeptidase M; Short=AP-M;AltName: Full=Microsomal aminopeptidase;AltName: Full=Myeloid plasma membrane glycoprotein CD13;AltName: Full=gp150;AltName: CD_antigen=CD13;
UniProt Information
AC/IDAC:P15144 ID:AMPN_HUMAN
Feature Table for 293-th site MUTAGEN: /note="Q->T: No change of receptor activity and HCoV-229E infection."
MUTAGEN: /note="EKQ->NKT: Complete loss of receptor activity and blocks HCoV-229E infection. No loss of enzymatic activity."
STRAND:
REGION: /note="Necessary and sufficient to mediate interaction with HCoV-229E" ECO:0000269|PubMed:8887485"
MUTAGEN: /note="DYVEKQAS->QSVEETAQ: No change in receptor activity and HCoV-229E infection."
MUTAGEN: /note="DYVEKQAS->QSVNEQAQ: No change in receptor activity and HCoV-229E infection."
MUTAGEN: /note="DYVEKQAS->QSVNETAQ: Complete loss of receptor activity and blocks HCoV-229E infection. No loss of enzymatic activity."
REGION: /note="Metalloprotease"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Aminopeptidase N" /id="PRO_0000095081"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
K:15% S:13% E:12% N:11% Q:7% R:6% T:6% G:5% V:5% C:3% I:3% H:2% M:2% P:2% Y:2% A:1% D:1% L:1% F:1% W:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5lhd E (beta-strand) e (exposed) 75.5
3D Complex Information
Predicted Bind Molecules
homo:2
Templates for 3D complexes
homo [97770:TRF3_THEAC ] 1z5h_B_3_A_2 1z5h_B_4_A_1


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