Summary for the 75-th Site(R)

PID QueryLength FocusSite TITLE
29280 794 75 R RecName: Full=Furin ; EC=3.4.21.75 ;AltName: Full=Dibasic-processing enzyme;AltName: Full=Paired basic amino acid residue-cleaving enzyme; Short=PACE;Flags: Precursor;
UniProt Information
AC/IDAC:P09958 ID:FURIN_HUMAN
Feature Table for 75-th site MUTAGEN: /note="R->A: Loss of catalytic activity and, propeptide second cleavage and removal. Normal trafficking to the Golgi."
SITE: /note="Cleavage, second; by autolysis"
HELIX:
PROPEP: /note="Inhibition peptide" /id="PRO_0000027028"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
R:45% L:18% A:15% Q:10% E:9% K:3% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
6a8y H (alpha-helix) e (exposed) 82.2


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