Summary for the 308-th Site(Y)
PID QueryLength FocusSite TITLE
29280 794 308 Y RecName: Full=Furin ; EC=3.4.21.75 ;AltName: Full=Dibasic-processing enzyme;AltName: Full=Paired basic amino acid residue-cleaving enzyme; Short=PACE;Flags: Precursor;
UniProt Information
AC/IDAC:P09958 ID:FURIN_HUMAN
Feature Table for 308-th site BINDING: /ligand="substrate" ECO:0000305|PubMed:25974265, ECO:0007744|PDB:4OMC, ECO:0007744|PDB:4OMD, ECO:0007744|PDB:4RYD"
TURN:
DOMAIN: /note="Peptidase S8"
TOPO_DOM: /note="Lumenal"
CHAIN: /note="Furin" /id="PRO_0000027029"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
Y:63% S:11% V:11% A:8% F:5%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5jmo T (Hbond turn) b (buried) 3.5
3D Complex Information
Predicted Bind Molecules
hetero:48 homo:2 compound:11 metal:27
Templates for 3D complexes
hetero [7650 ] 1p8j_A_1_I_1 1p8j_B_1_J_1 1p8j_C_1_K_1 1p8j_D_1_L_1 1p8j_E_1_M_1 1p8j_F_1_N_1 1p8j_G_1_O_1 1p8j_G_2_O_2 1p8j_H_1_P_1 5jmo_A_1_E_1 5jmo_B_1_F_1 [4510 ] 1r64_A_1_C_1 [4483 ] 4omc_A_1_G_1 4omc_B_1_H_1 4omc_C_1_I_1 4omc_D_1_J_1 4omc_E_1_K_1 4omc_F_1_L_1 4omd_A_1_G_1 4omd_B_1_H_1 4omd_C_1_I_1 4omd_D_1_J_1 4omd_E_1_K_1 4omd_F_1_L_1 5jxh_A_1_B_1 5jxj_A_1_B_1 [7166 ] 4ryd_A_1_G_1 4ryd_B_1_H_1 4ryd_C_1_I_1 4ryd_D_1_J_1 4ryd_E_1_K_1 4ryd_F_1_L_1 6eqw_A_1_B_1 [7167 ] 6eqv_A_1_B_1 [2822 ] 6eqx_A_1_B_1 [9000 ] 6hlb_A_1_B_1 [8124 ] 6hld_A_1_B_1 [5189 ] 6hle_A_1_B_1 6hzc_A_1_B_1 [2308 ] 6hza_A_1_B_1 [2162 ] 6hzb_A_1_B_1 [2831 ] 6hzd_A_1_B_1 [9019 ] 6yd2_A_1_B_1 6yd3_A_1_B_1 [10387 ] 6yd4_A_1_B_1 8oyh_A_1_B_1 [9088 ] 6yd7_A_1_B_1 [7192 ] 8b4x_A_1_B_1 homo [64966:SUBS_BACLE ] 3bx1_A_1_A_2 3bx1_A_2_A_1 compound [1N ] 5mim_A_1_K_1 [XTA ] 7lcu_A_1_F_1 [UYQ ] 7o1w_A_1_C_1 7o1y_A_1_C_1 [UYT ] 7o20_A_1_B_1 [I1G ] 7qxy_A_1_J_1 [I0M ] 7qxz_A_1_H_1 [I0T ] 7qy0_A_1_B_1 [I0W ] 7qy1_A_1_B_1 [I0Q ] 7qy2_A_1_B_1 [F05 ] 8b4w_A_1_C_1 metal [CA ] 1c9j_A_1_D_1 1c9m_A_1_D_1 1c9n_A_1_D_1 1gci_A_1_D_1 1iav_A_1_D_1 1jea_A_1_C_1 1mpt_A_1_C_1 1ndq_A_1_C_1 1ndu_A_1_C_1 1st3_A_1_C_1 1svn_A_1_C_1 1tk2_A_1_C_1 5yl7_A_1_F_1 [NA ] 3bx1_A_1_S_1 3bx1_A_2_S_2 3bx1_B_1_BA_1 3bx1_B_2_BA_2 4cfy_A_1_C_1 4cfz_A_1_C_1 4cg0_A_1_C_1 4omd_A_1_R_1 4omd_C_1_DA_1 4omd_E_1_PA_1 4omd_F_1_VA_1 5jxi_A_1_F_1 6y5s_A_1_C_1 6y5t_A_1_C_1


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