Summary for the 258-th Site(D)
PID QueryLength FocusSite TITLE
29280 794 258 D RecName: Full=Furin ; EC=3.4.21.75 ;AltName: Full=Dibasic-processing enzyme;AltName: Full=Paired basic amino acid residue-cleaving enzyme; Short=PACE;Flags: Precursor;
UniProt Information
AC/IDAC:P09958 ID:FURIN_HUMAN
Feature Table for 258-th site BINDING: /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="3" ECO:0000269|PubMed:25974265, ECO:0007744|PDB:4OMC, ECO:0007744|PDB:4OMD, ECO:0007744|PDB:4RYD"
BINDING: /ligand="substrate" ECO:0000305|PubMed:25974265, ECO:0007744|PDB:4OMC, ECO:0007744|PDB:4OMD, ECO:0007744|PDB:4RYD"
DOMAIN: /note="Peptidase S8"
TOPO_DOM: /note="Lumenal"
CHAIN: /note="Furin" /id="PRO_0000027029"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
D:50% S:13% G:9% V:7% A:6% E:6% Y:3% R:1% I:1% L:1% K:1% P:1% T:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5jmo (coil) e (exposed) 32.1
3D Complex Information
Predicted Bind Molecules
hetero:60 compound:7 metal:71
Templates for 3D complexes
hetero [4027 ] 1ot5_A_1_C_1 1ot5_B_1_D_1 [7650 ] 1p8j_A_1_I_1 1p8j_B_1_J_1 1p8j_C_1_K_1 1p8j_D_1_L_1 1p8j_E_1_M_1 1p8j_F_1_N_1 1p8j_G_1_O_1 1p8j_G_2_O_2 1p8j_H_1_P_1 5jmo_A_1_E_1 5jmo_B_1_F_1 [4510 ] 1r64_A_1_C_1 1r64_B_1_D_1 [10496 ] 1tk2_A_1_B_1 [7468 ] 2id4_A_1_C_1 2id4_B_1_D_1 [45085:IAAS_HORVU ] 3bx1_A_1_D_1 3bx1_A_2_D_2 3bx1_B_1_C_1 3bx1_B_2_C_2 [22846:Q868D6_PLAFA ] 4lvn_A_1_D_1 4lvo_A_1_D_1 [4483 ] 4omc_A_1_G_1 4omc_B_1_H_1 4omc_C_1_I_1 4omc_D_1_J_1 4omc_E_1_K_1 4omc_F_1_L_1 4omd_A_1_G_1 4omd_B_1_H_1 4omd_C_1_I_1 4omd_D_1_J_1 4omd_E_1_K_1 4omd_F_1_L_1 5jxh_A_1_B_1 5jxj_A_1_B_1 [7166 ] 4ryd_A_1_G_1 4ryd_B_1_H_1 4ryd_C_1_I_1 4ryd_D_1_J_1 4ryd_E_1_K_1 4ryd_F_1_L_1 6eqw_A_1_B_1 [7167 ] 6eqv_A_1_B_1 [2822 ] 6eqx_A_1_B_1 [9000 ] 6hlb_A_1_B_1 [8124 ] 6hld_A_1_B_1 [5189 ] 6hle_A_1_B_1 6hzc_A_1_B_1 [2308 ] 6hza_A_1_B_1 [2162 ] 6hzb_A_1_B_1 [2831 ] 6hzd_A_1_B_1 [9019 ] 6yd2_A_1_B_1 6yd3_A_1_B_1 [10387 ] 6yd4_A_1_B_1 8oyh_A_1_B_1 [9088 ] 6yd7_A_1_B_1 [7192 ] 8b4x_A_1_B_1 compound [UYN ] 7o1u_A_1_B_1 [UYQ ] 7o1w_A_1_B_1 7o1y_A_1_B_1 [UYT ] 7o20_A_1_C_1 [UYW ] 7o22_A_1_M_1 [BEN ] 8b4v_A_1_B_1 [F05 ] 8b4w_A_1_B_1 metal [CA ] 1ot5_A_1_H_1 1ot5_B_1_L_1 1p8j_A_1_U_1 1p8j_B_1_IA_1 1p8j_C_1_QA_1 1p8j_D_1_YA_1 1p8j_E_1_KB_1 1p8j_F_1_XB_1 1p8j_G_1_IC_1 1p8j_G_2_IC_2 1p8j_H_1_RC_1 1r64_A_1_I_1 1r64_B_1_P_1 2id4_A_1_H_1 2id4_B_1_M_1 4omc_A_1_R_1 4omc_B_1_Z_1 4omc_C_1_HA_1 4omc_D_1_PA_1 4omc_E_1_XA_1 4omc_F_1_FB_1 4omd_A_1_P_1 4omd_B_1_V_1 4omd_C_1_BA_1 4omd_D_1_HA_1 4omd_E_1_NA_1 4omd_F_1_TA_1 4ryd_A_1_Q_1 4ryd_B_1_X_1 4ryd_C_1_EA_1 4ryd_D_1_LA_1 4ryd_E_1_SA_1 4ryd_F_1_ZA_1 4z2a_A_1_E_1 5jmo_A_1_K_1 5jmo_B_1_Q_1 5jxg_A_1_D_1 5jxh_A_1_E_1 5mim_A_1_D_1 6eqv_A_1_E_1 6eqw_A_1_E_1 6eqx_A_1_E_1 6hlb_A_1_E_1 6hld_A_1_E_1 6hle_A_1_E_1 6hza_A_1_E_1 6hzb_A_1_E_1 6hzc_A_1_E_1 6hzd_A_1_E_1 6yd2_A_1_E_1 6yd3_A_1_E_1 6yd4_A_1_E_1 6yd7_A_1_E_1 7lcu_A_1_E_1 7o1u_A_1_E_1 7o1w_A_1_G_1 7o1y_A_1_G_1 7o20_A_1_G_1 7o22_A_1_D_1 7qxy_A_1_D_1 7qxz_A_1_D_1 7qy0_A_1_E_1 7qy1_A_1_E_1 7qy2_A_1_E_1 8b4v_A_1_F_1 8b4w_A_1_G_1 8b4x_A_1_E_1 8oyh_A_1_E_1 [NA ] 7qy0_A_1_I_1 7qy1_A_1_I_1 7qy2_A_1_I_1


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