Summary for the 205-th Site(V)
PID QueryLength FocusSite TITLE
29280 794 205 V RecName: Full=Furin ; EC=3.4.21.75 ;AltName: Full=Dibasic-processing enzyme;AltName: Full=Paired basic amino acid residue-cleaving enzyme; Short=PACE;Flags: Precursor;
UniProt Information
AC/IDAC:P09958 ID:FURIN_HUMAN
Feature Table for 205-th site BINDING: /ligand="Ca(2+)" /ligand_id="ChEBI:CHEBI:29108" /ligand_label="1" ECO:0000269|PubMed:25974265, ECO:0007744|PDB:4OMC, ECO:0007744|PDB:4OMD, ECO:0007744|PDB:4RYD"
DOMAIN: /note="Peptidase S8"
TOPO_DOM: /note="Lumenal"
CHAIN: /note="Furin" /id="PRO_0000027029"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
V:26% L:14% A:12% T:8% E:5% I:5% S:5% C:4% K:4% N:3% Q:3% G:3% M:2% F:2% R:1% D:1% P:1% Y:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5jmo (coil) b (buried) 17.3
3D Complex Information
Predicted Bind Molecules
metal:237 precipitant:6
Templates for 3D complexes
metal [CA ] 1a2q_A_1_B_1 1af4_A_1_B_1 1ak9_A_1_B_1 1aqn_A_1_B_1 1au9_A_1_B_1 1be6_A_1_B_1 1be8_A_1_B_1 1bfk_A_1_B_1 1bfu_A_1_B_1 1c3l_A_1_B_1 1c9j_A_1_C_1 1c9m_A_1_C_1 1c9n_A_1_C_1 1cse_A_1_D_1 1dbi_A_1_B_1 1dbi_A_1_E_1 1gci_A_1_C_1 1iav_A_1_C_1 1jea_A_1_B_1 1lw6_A_1_C_1 1mee_A_1_C_1 1mpt_A_1_B_1 1ndq_A_1_B_1 1ndu_A_1_B_1 1ot5_A_1_I_1 1ot5_B_1_M_1 1oyv_A_1_D_1 1oyv_B_1_E_1 1p8j_A_1_T_1 1p8j_B_1_HA_1 1p8j_C_1_PA_1 1p8j_D_1_XA_1 1p8j_E_1_JB_1 1p8j_F_1_WB_1 1p8j_G_1_HC_1 1p8j_G_2_HC_2 1p8j_H_1_QC_1 1q5p_A_1_C_1 1r0r_A_1_D_1 1r64_A_1_J_1 1r64_B_1_Q_1 1s01_A_1_B_1 1s02_A_1_B_1 1sbc_A_1_B_1 1sbh_A_1_B_1 1sbi_A_1_B_1 1sbn_A_1_D_1 1sca_A_1_B_1 1scb_A_1_B_1 1scd_A_1_B_1 1scj_A_1_C_1 1scn_A_1_C_1 1sel_A_1_C_1 1sel_B_1_E_1 1sib_A_1_D_1 1st2_A_1_B_1 1st3_A_1_B_1 1sub_A_1_B_1 1sud_A_1_B_1 1sup_A_1_B_1 1svn_A_1_B_1 1tec_A_1_C_1 1thm_A_1_B_1 1tk2_A_1_D_1 1tm1_A_1_C_1 1tm1_A_2_C_2 1tm3_A_1_C_1 1tm3_A_2_C_2 1tm4_A_1_C_1 1tm4_A_2_C_2 1tm5_A_1_C_1 1tm5_A_2_C_2 1tm7_A_1_C_1 1tm7_A_2_C_2 1tm7_A_3_C_3 1tmg_A_1_C_1 1to1_A_1_C_1 1to2_A_1_C_1 1ubn_A_1_B_1 1v5i_A_1_D_1 1wsd_A_1_B_1 1y1k_A_1_C_1 1y33_A_1_C_1 1y34_A_1_C_1 1y34_A_2_C_2 1y3b_A_1_C_1 1y3b_A_2_C_2 1y3c_A_1_C_1 1y3c_A_2_C_2 1y3d_A_1_C_1 1y3d_A_2_C_2 1y3f_A_1_C_1 1y3f_A_2_C_2 1y48_A_1_C_1 1y48_A_2_C_2 1y4a_A_1_C_1 1y4d_A_1_C_1 1yja_A_1_B_1 1yjb_A_1_B_1 1yjc_A_1_B_1 1yu6_A_1_E_1 1yu6_B_1_F_1 2id4_A_1_I_1 2id4_B_1_N_1 2sec_A_1_C_1 2sic_A_1_C_1 2sic_A_2_C_2 2sni_A_1_C_1 2st1_A_1_B_1 2tec_A_1_C_1 2wuv_A_1_T_1 2wuw_A_1_E_1 3bx1_A_1_E_1 3bx1_A_2_E_2 3bx1_B_1_T_1 3bx1_B_2_T_2 3hjr_A_1_B_1 3lpa_A_1_C_1 3lpc_A_1_C_1 3lpd_A_1_B_1 3sic_A_1_C_1 3sic_A_2_C_2 3tec_A_1_C_1 3ti7_A_1_B_1 3ti9_A_1_B_1 3unx_A_1_F_1 3vyv_A_1_E_1 3vyv_B_1_G_1 3whi_A_1_C_1 3whi_A_2_C_2 3whi_B_1_D_1 3wqb_A_1_C_1 4c3u_A_1_O_1 4c3v_A_1_H_1 4cfy_A_1_B_1 4cfz_A_1_B_1 4cg0_A_1_B_1 4dww_A_1_C_1 4hx2_A_1_E_1 4hx2_C_1_Q_1 4lvn_A_1_F_1 4lvo_A_1_E_1 4omc_A_1_Q_1 4omc_B_1_Y_1 4omc_C_1_GA_1 4omc_D_1_OA_1 4omc_E_1_WA_1 4omc_F_1_EB_1 4omd_A_1_O_1 4omd_B_1_U_1 4omd_C_1_AA_1 4omd_D_1_GA_1 4omd_E_1_MA_1 4omd_F_1_SA_1 4ryd_A_1_P_1 4ryd_B_1_W_1 4ryd_C_1_DA_1 4ryd_D_1_KA_1 4ryd_E_1_RA_1 4ryd_F_1_YA_1 4tr2_A_1_C_1 4tr2_B_1_J_1 4z2a_A_1_B_1 5aqe_A_1_D_1 5arb_A_1_B_1 5arc_A_1_B_1 5ard_A_1_B_1 5gl8_B_1_D_1 5jmo_A_1_J_1 5jmo_B_1_P_1 5jxg_A_1_C_1 5jxh_A_1_D_1 5jxi_A_1_B_1 5jxj_A_1_C_1 5mim_A_1_C_1 5sic_A_1_C_1 5sic_A_2_C_2 5yl7_A_1_C_1 6dwq_A_1_P_1 6eqv_A_1_D_1 6eqw_A_1_D_1 6eqx_A_1_D_1 6hlb_A_1_D_1 6hld_A_1_D_1 6hle_A_1_D_1 6hza_A_1_D_1 6hzb_A_1_D_1 6hzc_A_1_D_1 6hzd_A_1_D_1 6o44_A_1_C_1 6o44_B_1_J_1 6pak_A_1_C_1 6pak_B_1_F_1 6y5s_A_1_B_1 6y5t_A_1_B_1 6yd2_A_1_D_1 6yd3_A_1_D_1 6yd4_A_1_D_1 6yd7_A_1_D_1 7lcu_A_1_B_1 7o1u_A_1_D_1 7o1w_A_1_F_1 7o1y_A_1_F_1 7o20_A_1_F_1 7o22_A_1_C_1 7qxy_A_1_C_1 7qxz_A_1_C_1 7qy0_A_1_D_1 7qy1_A_1_D_1 7qy2_A_1_D_1 7w2a_A_1_C_1 7w2a_B_1_F_1 8b4v_A_1_E_1 8b4w_A_1_F_1 8b4x_A_1_D_1 8coy_A_1_F_1 8coy_B_1_K_1 8coz_A_1_C_1 8coz_B_1_M_1 8cp0_A_1_B_1 8h7o_A_1_B_1 8h7p_A_1_C_1 8oyh_A_1_D_1 8pol_A_1_F_1 8pol_B_1_L_1 8qke_A_1_E_1 8qke_B_1_J_1 8qkg_A_1_F_1 8qkg_B_1_I_1 8qkj_A_1_E_1 8qkj_B_1_I_1 [NA ] 1av7_A_1_C_1 1avt_A_1_C_1 3vsb_A_1_C_1 6f9m_A_1_D_1 6f9m_B_1_G_1 [CL ] 2wuv_A_1_H_1 precipitant [1PE ] 1tm7_A_1_K_1 1tm7_A_2_K_2 1tm7_A_3_K_3 [ACN ] 2sbt_A_1_B_1 [IPA ] 4hx2_A_1_L_1 [EDO ] 6dwq_A_1_L_1


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