Summary for the 192-nd Site(N)
PID QueryLength FocusSite TITLE
29280 794 192 N RecName: Full=Furin ; EC=3.4.21.75 ;AltName: Full=Dibasic-processing enzyme;AltName: Full=Paired basic amino acid residue-cleaving enzyme; Short=PACE;Flags: Precursor;
UniProt Information
AC/IDAC:P09958 ID:FURIN_HUMAN
Feature Table for 192-th site BINDING: /ligand="substrate" ECO:0000305|PubMed:25974265, ECO:0007744|PDB:4OMC, ECO:0007744|PDB:4OMD, ECO:0007744|PDB:4RYD"
HELIX:
DOMAIN: /note="Peptidase S8"
TOPO_DOM: /note="Lumenal"
CHAIN: /note="Furin" /id="PRO_0000027029"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
N:62% D:12% G:6% S:4% T:4% H:3% F:3% E:2% P:2% L:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5jmo G (3/10-helix) b (buried) 7.3
3D Complex Information
Predicted Bind Molecules
hetero:66 compound:3 metal:1 precipitant:10
Templates for 3D complexes
hetero [17136:ICIC_HIRME ] 1cse_A_1_B_1 1mee_A_1_B_1 1sbn_A_1_B_1 1sib_A_1_B_1 1tec_A_1_B_1 2sec_A_1_B_1 3tec_A_1_B_1 [7650 ] 1p8j_A_1_I_1 1p8j_B_1_J_1 1p8j_C_1_K_1 1p8j_D_1_L_1 1p8j_E_1_M_1 1p8j_F_1_N_1 1p8j_G_1_O_1 1p8j_G_2_O_2 1p8j_H_1_P_1 5jmo_A_1_E_1 5jmo_B_1_F_1 [18390:SUBT_BACSU ] 1scj_A_1_B_1 [7468 ] 2id4_A_1_C_1 2id4_B_1_D_1 [45085:IAAS_HORVU ] 3bx1_A_1_C_1 3bx1_A_2_C_2 3bx1_A_1_D_1 3bx1_A_2_D_2 3bx1_B_1_C_1 3bx1_B_2_C_2 3bx1_B_1_D_1 3bx1_B_2_D_2 [4483 ] 4omc_A_1_G_1 4omc_B_1_H_1 4omc_C_1_I_1 4omc_D_1_J_1 4omc_E_1_K_1 4omc_F_1_L_1 4omd_A_1_G_1 4omd_B_1_H_1 4omd_C_1_I_1 4omd_D_1_J_1 4omd_E_1_K_1 4omd_F_1_L_1 5jxh_A_1_B_1 5jxj_A_1_B_1 [7166 ] 4ryd_A_1_G_1 4ryd_B_1_H_1 4ryd_C_1_I_1 4ryd_D_1_J_1 4ryd_E_1_K_1 4ryd_F_1_L_1 6eqw_A_1_B_1 [7167 ] 6eqv_A_1_B_1 [2822 ] 6eqx_A_1_B_1 [9000 ] 6hlb_A_1_B_1 [8124 ] 6hld_A_1_B_1 [5189 ] 6hle_A_1_B_1 6hzc_A_1_B_1 [2308 ] 6hza_A_1_B_1 [2162 ] 6hzb_A_1_B_1 [2831 ] 6hzd_A_1_B_1 [9019 ] 6yd2_A_1_B_1 6yd3_A_1_B_1 [10387 ] 6yd4_A_1_B_1 8oyh_A_1_B_1 [9088 ] 6yd7_A_1_B_1 [7192 ] 8b4x_A_1_B_1 [38857:A0A1D3UUC0_TANFO ] 8ehe_A_1_B_1 compound [1N ] 5mim_A_1_J_1 [GEB ] 6hle_A_1_M_1 [PTD ] 6hzc_A_1_M_1 metal [CL ] 4hx2_A_1_H_1 precipitant [DIO ] 1af4_A_1_G_1 1af4_A_1_H_1 1bfu_A_1_C_1 [CCN ] 1scb_A_1_G_1 2wuv_A_1_X_1 2wuw_A_1_H_1 [GOL ] 1v5i_A_1_E_1 [SO4 ] 4c3v_A_1_C_1 [IPA ] 4hx2_C_1_U_1 [EDO ] 6dwq_A_1_D_1


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