Summary for the 371-st Site(E)
PID QueryLength FocusSite TITLE
26866 740 371 E RecName: Full=ATP-dependent RNA helicase DDX1; EC=3.6.4.13 ;AltName: Full=DEAD box protein 1;AltName: Full=DEAD box protein retinoblastoma; Short=DBP-RB;
UniProt Information
AC/IDAC:Q92499 ID:DDX1_HUMAN
Feature Table for 371-th site MUTAGEN: /note="E->G: Inhibits the transcriptional activity of RELA and attenuates NF-kappa-B-mediated gene expression." ECO:0000269|PubMed:24870230"
MUTAGEN: /note="E->Q: Abolishes ability to promote guanylylation of RTCB." ECO:0000269|PubMed:24870230"
MOTIF: /note="DEAD box"
DOMAIN: /note="Helicase ATP-binding"
REGION: /note="Interaction with dsRNA"
REGION: /note="Necessary for interaction with RELA"
CHAIN: /note="ATP-dependent RNA helicase DDX1" /id="PRO_0000054986"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
E:87% K:8% N:5%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8tbx T (Hbond turn) b (buried) 13.6
3D Complex Information
Predicted Bind Molecules
homo:2 compound:43 metal:65 precipitant:37
Templates for 3D complexes
homo [62217:O97032_DUGJA ] 1wrb_A_1_B_2 1wrb_B_2_A_1 compound [ANP ] 2db3_E_1_J_1 2db3_F_1_L_1 2db3_G_1_N_1 2db3_H_1_P_1 2hyi_E_1_L_1 2hyi_I_1_N_1 2j0q_A_1_L_1 2j0q_B_1_N_1 2j0s_A_1_G_1 2xb2_A_1_O_1 2xb2_K_1_Q_1 3fht_A_1_G_1 3fht_B_1_L_1 3g0h_A_1_C_1 3i5x_A_1_C_1 3i5y_A_1_C_1 3sqw_A_1_C_1 3sqx_A_1_C_1 4d25_A_1_C_1 5e7m_A_1_B_1 5zc9_A_1_C_1 6b4j_E_1_L_1 6b4j_F_1_P_1 6b4k_A_1_D_1 6b4k_B_1_H_1 6l5n_A_1_E_1 6l5n_B_1_G_1 6xki_A_1_C_1 7znj_A_1_FA_1 7znj_F_1_HA_1 7znj_K_1_JA_1 7znj_P_1_LA_1 7znj_U_1_NA_1 7znj_Z_1_PA_1 [ADP ] 2pl3_A_1_C_1 5dtu_A_1_B_1 8arp_A_1_G_1 8arp_C_1_L_1 8arp_E_1_Q_1 8arp_F_1_V_1 [ATP ] 6qdv_D_1_JB_1 [08T ] 7liu_A_1_F_1 7liu_B_1_H_1 metal [MG ] 1xtj_A_1_B_1 2db3_E_1_I_1 2db3_F_1_K_1 2db3_G_1_M_1 2db3_H_1_O_1 2hyi_E_1_K_1 2hyi_I_1_M_1 2j0q_A_1_K_1 2j0q_B_1_M_1 2j0s_A_1_F_1 2pl3_A_1_B_1 2xb2_A_1_N_1 2xb2_K_1_P_1 3fht_A_1_E_1 3fht_B_1_H_1 3i5x_A_1_D_1 3i61_A_1_E_1 3i62_A_1_E_1 3ly5_A_1_E_1 3pew_A_1_D_1 3pey_A_1_D_1 3sqw_A_1_D_1 3sqx_A_1_D_1 4d25_A_1_D_1 4d26_A_1_E_1 4ljy_A_1_C_1 4tyw_A_1_C_1 4tyy_B_1_E_1 4tz0_A_1_E_1 4tz6_A_1_E_1 5elx_A_1_D_1 5h1y_A_1_D_1 5h1y_B_1_F_1 5xjc_UA_1_UB_1 5yzg_FA_1_UB_1 5zc9_A_1_D_1 6b4j_E_1_K_1 6b4k_B_1_G_1 6l5n_A_1_F_1 6l5n_B_1_I_1 6qdv_D_1_IB_1 6uv1_A_1_G_1 6uv1_B_1_N_1 6uv2_A_1_E_1 6uv3_A_1_E_1 6uv4_A_1_E_1 7liu_A_1_E_1 7liu_B_1_G_1 7pli_A_1_O_1 7pli_C_1_R_1 7pli_E_1_U_1 7pli_G_1_X_1 7pli_I_1_AA_1 7pli_K_1_DA_1 7pmm_A_1_G_1 7pmq_A_1_K_1 7pmq_B_1_N_1 7pmq_C_1_Q_1 7pmq_D_1_T_1 8arp_A_1_I_1 8arp_C_1_N_1 8enk_A_1_H_1 8enk_B_1_K_1 8ia0_Y_1_PB_1 8tbx_A_1_C_1 precipitant [EDO ] 2zu6_A_1_H_1 [AF3 ] 3ex7_C_1_L_1 3ex7_G_1_O_1 [BEF ] 3i61_A_1_D_1 3pew_A_1_E_1 3pey_A_1_E_1 4tyn_B_1_D_1 4tyw_A_1_E_1 4tyy_B_1_C_1 4tz0_A_1_D_1 4tz6_A_1_C_1 5elx_A_1_E_1 5sup_A_1_K_1 5sup_B_1_N_1 5sup_C_1_Q_1 6uv1_A_1_F_1 6uv1_B_1_M_1 6uv2_A_1_D_1 6uv3_A_1_D_1 6uv4_A_1_D_1 7pli_A_1_N_1 7pli_C_1_Q_1 7pli_E_1_T_1 7pli_G_1_W_1 7pli_I_1_Z_1 7pli_K_1_CA_1 7pmm_A_1_F_1 7pmm_B_1_I_1 7pmq_A_1_J_1 7pmq_B_1_M_1 7pmq_C_1_P_1 7pmq_D_1_S_1 8enk_A_1_G_1 8enk_B_1_J_1 [ALF ] 3i62_A_1_D_1 [GOL ] 4c9b_A_1_J_1 [PO4 ] 4d26_A_1_D_1


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