Summary for the 1629-th Site(V)

PID QueryLength FocusSite TITLE
18363 4405 1629 V RecName: Full=Replicase polyprotein 1a; Short=pp1a;AltName: Full=ORF1a polyprotein;Contains: RecName: Full=Host translation inhibitor nsp1; AltName: Full=Leader protein; AltName: Full=Non-structural protein 1; Short=nsp1;Contains: RecName: Full=Non-structural protein 2; Short=nsp2; AltName: Full=p65 homolog;Contains: RecName: Full=Papain-like protease nsp3 ; EC=3.4.19.12 ; EC=3.4.22.-; AltName: Full=Non-structural protein 3; Short=nsp3; AltName: Full=PL2-PRO; AltName: Full=Papain-like proteinase; Short=PL-PRO;Contains: RecName: Full=Non-structural protein 4; Short=nsp4;Contains: RecName: Full=3C-like proteinase nsp5; Short=3CL-PRO; Short=3CLp; EC=3.4.22.69; AltName: Full=Main protease; Short=Mpro ; AltName: Full=Non-structural protein 5; Short=nsp5; AltName: Full=SARS coronavirus main proteinase;Contains: RecName: Full=Non-structural protein 6; Short=nsp6;Contains: RecName: Full=Non-structural protein 7; Short=nsp7;Contains: RecName: Full=Non-structural protein 8; Short=nsp8;Contains: RecName: Full=RNA-capping enzyme subunit nsp9; AltName: Full=Non-structural protein 9; Short=nsp9; EC=2.7.7.50 ;Contains: RecName: Full=Non-structural protein 10; Short=nsp10; AltName: Full=Growth factor-like peptide; Short=GFL;Contains: RecName: Full=Non-structural protein 11; Short=nsp11;
UniProt Information
AC/IDAC:P0DTC1 ID:R1A_SARS2
Feature Table for 1629-th site MUTAGEN: /note="V->A: Partial loss of ISG15 cleavage in vitro."
HELIX:
CHAIN: /note="Papain-like protease nsp3" /id="PRO_0000449637"
TOPO_DOM: /note="Cytoplasmic"
CHAIN: /note="Replicase polyprotein 1a" /id="PRO_0000449634"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
V:37% L:21% S:17% A:6% T:6% I:5% R:1% N:1% D:1% Q:1% E:1% G:1% K:1% F:1% P:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
6wuu H (alpha-helix) e (exposed) 54.0
3D Complex Information
Predicted Bind Molecules
hetero:12 homo:3 compound:2
Templates for 3D complexes
hetero [39611:ISG15_HUMAN ] 7rbs_A_1_B_1 7rbs_C_1_D_1 7rbs_E_1_F_1 7rbs_G_1_H_1 7rbs_I_1_J_1 [19431:UBB_HUMAN ] 7uv5_A_1_C_1 [25297:RL40_HUMAN ] 8cx9_A_1_G_1 8cx9_A_1_H_1 8cx9_B_1_E_1 8cx9_B_1_F_1 8cx9_C_1_I_1 8cx9_D_1_K_1 homo [71385:R1AB_SARS2 ] 6xg3_A_1_A_2 6xg3_A_2_A_1 7cjd_A_1_D_1 compound [YOO ] 8g62_A_1_M_1 8g62_C_1_U_1


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