Summary for the 184-th Site(D)

PID QueryLength FocusSite TITLE
13847 468 184 D RecName: Full=Interleukin-6 receptor subunit alpha ; Short=IL-6 receptor subunit alpha; Short=IL-6R subunit alpha; Short=IL-6R-alpha; Short=IL-6RA;AltName: Full=IL-6R 1;AltName: Full=Membrane glycoprotein 80; Short=gp80;AltName: CD_antigen=CD126;Contains: RecName: Full=Soluble interleukin-6 receptor subunit alpha ; Short=sIL6R ;Flags: Precursor;
UniProt Information
AC/IDAC:P08887 ID:IL6RA_HUMAN
Feature Table for 184-th site MUTAGEN: /note="D->T: 30% decrease of ligand-binding and IL6 signaling."
DOMAIN: /note="Fibronectin type-III 1"
CHAIN: /note="Soluble interleukin-6 receptor subunit alpha" /id="PRO_0000450730"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Interleukin-6 receptor subunit alpha" /id="PRO_0000010895"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
E:26% S:16% D:9% A:8% L:8% W:6% F:5% P:5% N:4% Y:4% H:2% R:1% Q:1% G:1% I:1% K:1% T:1% V:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
1n26 (coil) b (buried) 5.6
3D Complex Information
Predicted Bind Molecules
compound:2
Templates for 3D complexes
compound [CYS ] 1n26_A_1_H_1 1n26_A_2_H_2


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