Summary for the 371-st Site(E)
PID QueryLength FocusSite TITLE
10705 740 371 E RecName: Full=ATP-dependent RNA helicase DDX1; EC=3.6.4.13 ;AltName: Full=DEAD box protein 1;AltName: Full=DEAD box protein retinoblastoma; Short=DBP-RB;
UniProt Information
AC/IDAC:Q92499 ID:DDX1_HUMAN
Feature Table for 371-th site MUTAGEN: /note="E->G: Inhibits the transcriptional activity of RELA and attenuates NF-kappa-B-mediated gene expression." ECO:0000269|PubMed:24870230"
MUTAGEN: /note="E->Q: Abolishes ability to promote guanylylation of RTCB." ECO:0000269|PubMed:24870230"
MOTIF: /note="DEAD box"
DOMAIN: /note="Helicase ATP-binding"
REGION: /note="Interaction with dsRNA"
REGION: /note="Necessary for interaction with RELA"
CHAIN: /note="ATP-dependent RNA helicase DDX1" /id="PRO_0000054986"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
E:87% K:8% N:5%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8tbx T (Hbond turn) b (buried) 13.6
3D Complex Information
Predicted Bind Molecules
metal:1
Templates for 3D complexes
metal [MG ] 8tbx_A_1_C_1


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