Summary for the 3431-st Site(A)
PID QueryLength FocusSite TITLE
19598 4382 3431 A RecName: Full=Replicase polyprotein 1a; Short=pp1a;AltName: Full=ORF1a polyprotein;Contains: RecName: Full=Host translation inhibitor nsp1; AltName: Full=Leader protein; AltName: Full=Non-structural protein 1; Short=nsp1;Contains: RecName: Full=Non-structural protein 2; Short=nsp2; AltName: Full=p65 homolog;Contains: RecName: Full=Papain-like protease nsp3; Short=PL-PRO; EC=3.4.19.12 ; EC=3.4.22.- ; AltName: Full=Non-structural protein 3; Short=nsp3; AltName: Full=PL2-PRO;Contains: RecName: Full=Non-structural protein 4; Short=nsp4;Contains: RecName: Full=3C-like proteinase nsp5; Short=3CL-PRO; Short=3CLp; EC=3.4.22.69 ; AltName: Full=Main protease; Short=Mpro; AltName: Full=Non-structural protein 5; Short=nsp5; AltName: Full=SARS coronavirus main proteinase;Contains: RecName: Full=Non-structural protein 6; Short=nsp6;Contains: RecName: Full=Non-structural protein 7; Short=nsp7;Contains: RecName: Full=Non-structural protein 8; Short=nsp8;Contains: RecName: Full=RNA-capping enzyme subunit nsp9; AltName: Full=Non-structural protein 9; Short=nsp9; EC=2.7.7.50;Contains: RecName: Full=Non-structural protein 10; Short=nsp10; AltName: Full=Growth factor-like peptide; Short=GFL;Contains: RecName: Full=Non-structural protein 11; Short=nsp11;
UniProt Information
AC/IDAC:P0C6U8 ID:R1A_SARS
Feature Table for 3431-th site CHAIN: /note="3C-like proteinase nsp5" /id="PRO_0000338259"
DOMAIN: /note="Peptidase C30"
TOPO_DOM: /note="Cytoplasmic"
CHAIN: /note="Replicase polyprotein 1a" /id="PRO_0000338254"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
A:28% L:24% V:19% H:11% M:11% P:7%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
5b6o (coil) e (exposed) 96.4
3D Complex Information
Predicted Bind Molecules
hetero:72 homo:6 compound:182 metal:2 precipitant:14
Templates for 3D complexes
hetero [2880 ] 1uk4_B_1_D_1 [7652 ] 2amq_A_1_C_1 2hob_A_1_B_1 2hob_A_2_B_2 3iwm_A_1_E_1 3iwm_A_2_E_2 3iwm_C_1_G_1 3iwm_C_2_G_2 3iwm_D_1_H_1 3iwm_D_2_H_2 6lu7_A_1_B_1 6lu7_A_2_B_2 [3373 ] 2q6g_A_1_C_1 [3160 ] 2q6g_B_1_D_1 [7168 ] 3atw_A_1_C_1 [7260 ] 3avz_A_1_B_1 [4854 ] 3aw0_A_1_B_1 3aw0_A_2_B_2 [5217 ] 3sna_A_1_B_1 3sna_A_2_B_2 [5239 ] 3snb_A_1_B_1 3snb_A_2_B_2 [4906 ] 3snc_A_1_B_1 3snc_A_2_B_2 [4909 ] 3sne_A_1_B_1 3sne_A_2_B_2 [4677 ] 3vb4_A_1_C_1 3vb4_B_1_D_1 3vb5_A_1_C_1 3vb5_B_1_D_1 [7187 ] 6xbi_A_1_C_1 [8234:R1AB_SARS2 ] 7dvx_A_1_B_1 7dvx_A_2_B_2 [8238:R1AB_SARS2 ] 7dw6_A_1_B_1 7dw6_A_2_B_2 [785:R1AB_SARS2 ] 7lmc_C_1_A_1 7lmc_F_1_D_1 7mb4_A_1_E_1 7mb4_B_1_F_1 7mb4_C_1_G_1 7mb4_D_1_H_1 [6104 ] 7m2p_A_1_B_1 7m2p_A_2_B_2 [708:R1AB_SARS2 ] 7mb5_A_1_C_1 7mb5_B_1_D_1 [717:R1AB_SARS2 ] 7mb6_A_1_C_1 [784:R1AB_SARS2 ] 7mb8_A_1_E_1 7mb8_B_1_F_1 7mb8_C_1_G_1 7mb8_D_2_H_2 [1221:R1AB_SARS2 ] 7n6n_A_1_C_1 [7305 ] 7n89_A_1_C_1 7n89_B_1_D_1 [10882 ] 7rnw_A_1_F_1 [10813 ] 7rnw_C_1_E_1 [10651 ] 7rnw_D_1_H_1 [2938:NEMO_HUMAN ] 7t2u_B_1_C_1 [3977 ] 7t70_A_1_C_1 7t70_B_1_D_1 [1242 ] 7t8r_A_1_B_1 7t8r_A_2_B_2 [2553 ] 7t9y_B_1_D_1 [2749 ] 7ta4_B_1_D_1 [1232 ] 7tb2_A_1_B_1 7tb2_A_2_B_2 [2413 ] 7tbt_A_1_B_1 7tbt_A_2_B_2 [2041 ] 7tc4_A_1_C_1 7tc4_B_1_D_1 [11774 ] 7z4s_A_1_D_1 [9057 ] 8s9z_A_1_B_1 8s9z_A_2_B_2 homo [69082:R1AB_SARS2 ] 7e5x_A_1_C_1 7rm2_A_1_A_2 7rm2_A_2_A_1 [71741:R1AB_SARS2 ] 7s82_A_1_B_1 7s82_C_1_D_1 8ey2_D_1_C_1 compound [I12 ] 1wof_A_1_C_1 1wof_B_1_D_1 [AZP ] 2a5i_A_1_B_1 2a5i_A_2_B_2 2a5k_B_1_D_1 [CY6 ] 2alv_A_1_B_1 2alv_A_2_B_2 [9IN ] 2amd_A_1_C_1 2amd_B_1_D_1 [ENB ] 2d2d_A_1_C_1 2d2d_B_1_D_1 [NOL ] 2gx4_A_1_B_1 2gx4_A_2_B_2 7jq5_A_1_B_1 7jq5_A_2_B_2 [ZU3 ] 2zu4_A_1_B_1 2zu4_A_2_B_2 [ZU5 ] 2zu5_A_1_B_1 2zu5_A_2_B_2 [G82 ] 3tiu_A_1_C_1 3tiu_A_2_C_2 [G83 ] 3tns_A_1_B_1 3tns_A_2_B_2 [G85 ] 3tnt_A_1_B_1 3tnt_A_2_B_2 [SFY ] 5rf8_A_1_E_1 5rf8_A_2_E_2 [UGS ] 5rgy_A_1_B_1 5rgy_A_2_B_2 [EJF ] 6lnq_A_1_B_1 [EOF ] 6lo0_A_1_B_1 7dgb_A_1_B_1 7dgb_A_2_B_2 [VDJ ] 6w2a_A_1_C_1 [QYS ] 6w2a_B_1_E_1 6xmk_B_1_D_1 [K36 ] 6wtt_A_1_D_1 6wtt_A_2_D_2 7d1m_A_1_C_1 [V2M ] 6xhl_A_1_C_1 6xhl_B_1_D_1 8dsu_A_1_D_1 8dsu_B_1_H_1 8dt9_B_1_H_1 8e4w_A_1_C_1 8e4w_B_1_D_1 [V3D ] 6xhn_A_1_C_1 6xhn_B_1_E_1 [V34 ] 6xho_A_1_D_1 6xho_B_1_E_1 [SV6 ] 6xqs_A_1_B_1 6xqs_A_2_B_2 6zrt_A_1_C_1 6zrt_A_2_C_2 7k6d_A_1_C_1 7k6d_A_2_C_2 7k6e_A_1_C_1 7k6e_A_2_C_2 7lb7_A_1_B_1 7lb7_A_2_B_2 7nbs_A_1_C_1 7nbs_A_2_C_2 [NNA ] 6xqt_A_1_C_1 6xqt_B_1_D_1 7jyc_A_1_B_1 7jyc_A_2_B_2 [V7G ] 6xr3_A_1_B_1 6xr3_A_2_B_2 [Q5T ] 6z2e_A_1_B_1 6z2e_A_2_B_2 [ALD ] 7be7_B_1_N_1 7bgp_B_1_L_1 7cuu_A_1_D_1 7cuu_B_1_I_1 7nf5_A_1_B_1 7nf5_A_2_B_2 7ng3_A_1_D_1 7ng3_B_1_E_1 7ng6_A_1_C_1 7ng6_B_1_F_1 [H63 ] 7dgg_B_1_D_1 [H6F ] 7dgh_A_1_B_1 7dgh_A_2_B_2 [H6L ] 7dgi_A_1_C_1 7dgi_B_1_D_1 [HUR ] 7e18_A_1_B_1 7e18_A_2_B_2 7ygq_A_1_C_1 7ygq_B_1_D_1 [HUO ] 7e19_A_1_B_1 7e19_A_2_B_2 [QOO ] 7gjj_A_1_E_1 [XZT ] 7grx_B_1_N_1 [XZO ] 7gry_B_1_N_1 [JAH ] 7gs3_A_1_D_1 [VJA ] 7jp0_A_1_B_1 7jp0_A_2_B_2 [VHV ] 7jq0_A_1_B_1 7jq0_A_2_B_2 [VHJ ] 7jq1_A_1_B_1 7jq1_A_2_B_2 [VHM ] 7jq2_A_1_B_1 7jq2_A_2_B_2 [VHP ] 7jq3_A_1_B_1 7jq3_A_2_B_2 [XM2 ] 7jq4_A_1_B_1 7jq4_A_2_B_2 [TG3 ] 7jt7_A_1_B_1 7jt7_A_2_B_2 7jw8_A_1_E_1 7jw8_D_1_I_1 [VR4 ] 7k0h_A_1_E_1 [XTJ ] 7lco_A_1_B_1 7lco_A_2_B_2 [XU4 ] 7lct_A_1_B_1 7lct_A_2_B_2 [XV4 ] 7ldl_A_1_C_1 7ldl_B_1_D_1 [YVA ] 7maw_A_1_C_1 7maw_B_1_D_1 [YVV ] 7mb3_A_1_G_1 7mb3_C_1_I_1 7mb3_F_2_L_2 [YWJ ] 7mbi_A_1_E_1 7mbi_B_1_F_1 7mbi_C_1_H_1 7mbi_D_2_I_2 [AG7 ] 7p35_A_1_C_1 7p35_B_1_D_1 [90I ] 7q5e_A_1_C_1 [4IT ] 7r7h_A_1_C_1 7r7h_B_1_D_1 [7V2 ] 7rvm_A_1_B_1 7rvm_A_2_B_2 [7VB ] 7rvn_A_1_B_1 7rvn_A_2_B_2 [7VI ] 7rvo_A_1_C_1 7rvo_B_1_D_1 [7VQ ] 7rvp_A_1_C_1 [7VW ] 7rvq_A_1_B_1 7rvq_A_2_B_2 [7W5 ] 7rvr_A_1_B_1 7rvr_A_2_B_2 [81L ] 7rvs_A_1_B_1 7rvs_A_2_B_2 [7XT ] 7rvu_A_1_B_1 7rvu_A_2_B_2 [7Y2 ] 7rvv_A_1_B_1 [7YI ] 7rvx_A_1_C_1 7rvx_B_1_D_1 [7YQ ] 7rvy_A_1_B_1 7rvy_A_2_B_2 [I80 ] 7sdc_A_1_B_1 7sdc_A_2_B_2 [99W ] 7sgh_A_1_E_1 7sgh_B_1_F_1 7sgh_C_1_G_1 7sgh_D_1_H_1 [Y48 ] 7tiy_A_1_B_1 7tiy_A_2_B_2 [4WI ] 7vlo_A_1_C_1 8dcz_A_1_C_1 8dcz_B_1_D_1 [59S ] 7wo3_A_1_B_1 7wo3_A_2_B_2 [BOV ] 7xar_A_1_H_1 7xar_B_1_K_1 [MJ0 ] 8aj0_A_1_C_1 [QQL ] 8bga_A_1_C_1 [U6Y ] 8dzb_A_1_C_1 8dzb_A_2_C_2 [YFK ] 8fy7_A_1_C_1 8fy7_B_1_D_1 [UED ] 8ig5_A_1_C_1 [ZQB ] 8tbe_A_1_C_1 8tbe_B_1_D_1 [W28 ] 8uab_A_1_B_1 8uab_A_2_B_2 [WTV ] 8uia_B_1_F_1 [A1ADS ] 8uif_B_1_D_1 [WYR ] 8uld_A_1_B_1 8uld_A_2_B_2 metal [CL ] 7gnp_A_1_P_1 7gnq_A_1_P_1 precipitant [DMS ] 7glu_A_1_L_1 7glw_A_1_L_1 7gnf_A_1_K_1 7gng_A_1_L_1 7gnk_A_1_K_1 7gnq_A_1_K_1 7gns_A_1_I_1 7gnt_A_1_G_1 7gnu_A_1_H_1 7grs_A_1_M_1 7t70_A_1_I_1 [GOL ] 7nts_A_1_G_1 7nts_A_2_G_2 7t70_A_1_IA_1


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