Summary for the 55-th Site(N)

PID QueryLength FocusSite TITLE
13847 468 55 N RecName: Full=Interleukin-6 receptor subunit alpha ; Short=IL-6 receptor subunit alpha; Short=IL-6R subunit alpha; Short=IL-6R-alpha; Short=IL-6RA;AltName: Full=IL-6R 1;AltName: Full=Membrane glycoprotein 80; Short=gp80;AltName: CD_antigen=CD126;Contains: RecName: Full=Soluble interleukin-6 receptor subunit alpha ; Short=sIL6R ;Flags: Precursor;
UniProt Information
AC/IDAC:P08887 ID:IL6RA_HUMAN
Feature Table for 55-th site CARBOHYD: /note="N-linked (GlcNAc...) asparagine" ECO:0000269|PubMed:28060820"
MUTAGEN: /note="N->A: Strongly induces cleavage and sIL6R levels. No effect on IL6R signaling; when associated with A-93, A-221, A-245 and A-350. Loss of cleavage by ADAM17; when associated with A-93, A-221, A-245 and A-350."
DOMAIN: /note="Ig-like C2-type"
CHAIN: /note="Soluble interleukin-6 receptor subunit alpha" /id="PRO_0000450730"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Interleukin-6 receptor subunit alpha" /id="PRO_0000010895"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
D:24% N:19% G:17% A:4% L:4% E:3% K:3% S:3% T:3% V:3% R:2% Q:2% I:2% F:2% P:2% Y:2% C:1% H:1% M:1% W:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
1n26 (coil) e (exposed) 72.1
3D Complex Information
Predicted Bind Molecules
compound:4
Templates for 3D complexes
compound [NAG ] 1n26_A_1_E_1 1n26_A_2_E_2 8d82_A_1_R_1 8d82_D_1_AA_1


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