Summary for the 254-th Site(E)

PID QueryLength FocusSite TITLE
13847 468 254 E RecName: Full=Interleukin-6 receptor subunit alpha ; Short=IL-6 receptor subunit alpha; Short=IL-6R subunit alpha; Short=IL-6R-alpha; Short=IL-6RA;AltName: Full=IL-6R 1;AltName: Full=Membrane glycoprotein 80; Short=gp80;AltName: CD_antigen=CD126;Contains: RecName: Full=Soluble interleukin-6 receptor subunit alpha ; Short=sIL6R ;Flags: Precursor;
UniProt Information
AC/IDAC:P08887 ID:IL6RA_HUMAN
Feature Table for 254-th site MUTAGEN: /note="E->A: 50% decrease of ligand-binding and IL6 signaling."
STRAND:
DOMAIN: /note="Fibronectin type-III 2"
CHAIN: /note="Soluble interleukin-6 receptor subunit alpha" /id="PRO_0000450730"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Interleukin-6 receptor subunit alpha" /id="PRO_0000010895"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
E:27% R:15% C:12% Q:11% F:10% D:6% S:4% W:4% N:3% G:3% H:3% L:2% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
1n26 E (beta-strand) b (buried) 15.6
3D Complex Information
Predicted Bind Molecules
hetero:1 homo:1 compound:1
Templates for 3D complexes
hetero [49624 ] 8j6f_C_1_B_1 homo [48779:IL6RB_HUMAN ] 1bqu_B_1_A_1 compound [MNB ] 1f42_A_1_D_1


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