Summary for the 245-th Site(N)
PID QueryLength FocusSite TITLE
13847 468 245 N RecName: Full=Interleukin-6 receptor subunit alpha ; Short=IL-6 receptor subunit alpha; Short=IL-6R subunit alpha; Short=IL-6R-alpha; Short=IL-6RA;AltName: Full=IL-6R 1;AltName: Full=Membrane glycoprotein 80; Short=gp80;AltName: CD_antigen=CD126;Contains: RecName: Full=Soluble interleukin-6 receptor subunit alpha ; Short=sIL6R ;Flags: Precursor;
UniProt Information
AC/IDAC:P08887 ID:IL6RA_HUMAN
Feature Table for 245-th site SITE: /note="Not glycosylated"
CARBOHYD: /note="N-linked (GlcNAc...) asparagine"
MUTAGEN: /note="N->A: Slightly induces cleavage and sIL6R levels.No effect on IL6R signaling; when associated with A-55, A-93, A-221 and A-350. Loss of cleavage by ADAM17; when associated with A-55, A-93, A-221 and A-350."
DOMAIN: /note="Fibronectin type-III 2"
CHAIN: /note="Soluble interleukin-6 receptor subunit alpha" /id="PRO_0000450730"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Interleukin-6 receptor subunit alpha" /id="PRO_0000010895"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment] 
S:27% D:21% R:14% K:13% L:7% N:5% F:5% A:1% Q:1% E:1% G:1% I:1% P:1% T:1% V:1%
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
1n26 (coil) e (exposed) 61.8
3D Complex Information
Predicted Bind Molecules
hetero:20 homo:1 otherpoly:4 compound:3
Templates for 3D complexes
hetero [48369:CSH_SHEEP ] 1f6f_B_1_A_1 [46264:PRL_HUMAN ] 3d48_B_1_A_1 [49140:PRL_HUMAN ] 3ew3_B_1_A_1 [45950:PRL_HUMAN ] 3mzg_B_1_A_1 3n06_B_1_A_1 3n0p_B_1_A_1 3ncb_B_1_A_1 3ncc_B_1_A_1 3nce_B_1_A_1 3ncf_B_1_A_1 3npz_B_1_A_1 [31866 ] 4grw_B_1_G_1 4grw_D_1_E_1 [52228:IL27A_HUMAN ] 7u7n_C_1_D_1 [49274:CLCF1_HUMAN ] 8d7h_A_1_B_1 8d7h_C_1_B_1 8d7h_D_1_E_1 8d7h_F_1_E_1 8d7r_B_1_A_1 [2993:IL6RA_HUMAN ] 8j6f_C_1_D_1 homo [78452:IL6RA_HUMAN ] 8iow_A_1_B_1 otherpoly [2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 1n26_A_1_B_1 1n26_A_2_B_2 [2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 8d82_A_1_G_1 8d82_D_1_L_1 compound [NAG ] 5fuc_C_1_H_1 5fuc_D_1_J_1 8iow_A_1_F_1


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