Summary for the 221-st Site(N)

PID QueryLength FocusSite TITLE
13847 468 221 N RecName: Full=Interleukin-6 receptor subunit alpha ; Short=IL-6 receptor subunit alpha; Short=IL-6R subunit alpha; Short=IL-6R-alpha; Short=IL-6RA;AltName: Full=IL-6R 1;AltName: Full=Membrane glycoprotein 80; Short=gp80;AltName: CD_antigen=CD126;Contains: RecName: Full=Soluble interleukin-6 receptor subunit alpha ; Short=sIL6R ;Flags: Precursor;
UniProt Information
AC/IDAC:P08887 ID:IL6RA_HUMAN
Feature Table for 221-th site CARBOHYD: /note="N-linked (GlcNAc...) asparagine" ECO:0000269|PubMed:28060820"
MUTAGEN: /note="N->A: No effect on cleavage or sIL6R levels. No effect on IL6R signaling; when associated with A-55, A-93, A-245 and A-350. Loss of cleavage by ADAM17; when associated with A-55, A-93, A-245 and A-350."
STRAND:
DOMAIN: /note="Fibronectin type-III 2"
CHAIN: /note="Soluble interleukin-6 receptor subunit alpha" /id="PRO_0000450730"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Interleukin-6 receptor subunit alpha" /id="PRO_0000010895"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
N:64% D:16% G:13% K:3% S:3% E:2% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
1n26 E (beta-strand) e (exposed) 67.3
3D Complex Information
Predicted Bind Molecules
otherpoly:4 compound:18
Templates for 3D complexes
otherpoly [2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose ] 3l5h_A_1_B_1 8d6a_B_1_D_1 8d74_A_1_E_1 8d7r_D_1_I_1 compound [NAG ] 1n26_A_1_D_1 1n26_A_2_D_2 5fuc_C_1_G_1 5fuc_D_1_I_1 7z0l_A_1_J_1 8d82_A_1_Q_1 8d82_C_1_T_1 8d82_D_1_Z_1 8d82_F_1_CA_1 8d85_D_1_J_1 8iow_A_1_E_1 8j6f_C_1_E_1 8qy4_B_1_Q_1 8qy4_D_1_V_1 8qy5_A_1_Q_1 8qy5_F_1_R_1 8qy6_A_1_Q_1 8qy6_F_1_R_1


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