Summary for the 217-th Site(D)

PID QueryLength FocusSite TITLE
13847 468 217 D RecName: Full=Interleukin-6 receptor subunit alpha ; Short=IL-6 receptor subunit alpha; Short=IL-6R subunit alpha; Short=IL-6R-alpha; Short=IL-6RA;AltName: Full=IL-6R 1;AltName: Full=Membrane glycoprotein 80; Short=gp80;AltName: CD_antigen=CD126;Contains: RecName: Full=Soluble interleukin-6 receptor subunit alpha ; Short=sIL6R ;Flags: Precursor;
UniProt Information
AC/IDAC:P08887 ID:IL6RA_HUMAN
Feature Table for 217-th site MUTAGEN: /note="D->V: Complete loss of ligand-binding."
DOMAIN: /note="Fibronectin type-III 1"
CHAIN: /note="Soluble interleukin-6 receptor subunit alpha" /id="PRO_0000450730"
TOPO_DOM: /note="Extracellular"
CHAIN: /note="Interleukin-6 receptor subunit alpha" /id="PRO_0000010895"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
D:67% L:11% E:6% G:4% N:3% H:3% S:3% T:3% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
1n26 (coil) e (exposed) 32.1
3D Complex Information
Predicted Bind Molecules
hetero:3 homo:1 precipitant:3
Templates for 3D complexes
hetero [49624 ] 4i18_E_1_C_1 [58863 ] 4i18_E_1_D_1 [2993:IL6RA_HUMAN ] 8j6f_C_1_D_1 homo [78452:IL6RA_HUMAN ] 8iow_A_1_B_1 precipitant [GOL ] 1bqu_A_1_G_1 1bqu_B_1_K_1 4i18_E_1_K_1


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