Summary for the 426-th Site(P)

PID QueryLength FocusSite TITLE
27558 918 426 P RecName: Full=Interleukin-6 receptor subunit beta ; Short=IL-6 receptor subunit beta; Short=IL-6R subunit beta; Short=IL-6R-beta; Short=IL-6RB;AltName: Full=CDw130;AltName: Full=Interleukin-6 signal transducer;AltName: Full=Membrane glycoprotein 130; Short=gp130 ;AltName: Full=Oncostatin-M receptor subunit alpha;AltName: CD_antigen=CD130;Flags: Precursor;
UniProt Information
AC/IDAC:P40189 ID:IL6RB_HUMAN
Feature Table for 426-th site VAR_SEQ: /note="Missing (in isoform 3)" /id="VSP_043716"
DOMAIN: /note="Fibronectin type-III 4"
VAR_SEQ: /note="Missing (in isoform 2)" /id="VSP_001685"
TOPO_DOM: /note="Extracellular"
VARIANT: /note="Missing (in STWS2; results in impaired cytokine- mediated signaling pathway with loss of response to IL-6, IL-11, IL-27, OSM and LIF; does not localize to the cell membrane)" /id="VAR_086951"
CHAIN: /note="Interleukin-6 receptor subunit beta" /id="PRO_0000010899"
Evolutionary Information
Percentages of Amino Acids in Homologous Proteins [show alignment]
P:42% A:12% G:7% S:7% E:5% R:4% I:4% T:4% K:3% Y:3% C:2% Q:2% V:2% N:1% D:1% L:1% F:1% 
3D Structure Information
Template For Monomer predicted SecStr predicted ExpBur Predicted Relative Acc(%)
8d82 (coil) e (exposed) 31.8
3D Complex Information
Predicted Bind Molecules
precipitant:1
Templates for 3D complexes
precipitant [EDO ] 3l5i_A_1_H_1


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